# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- UNC-93 PF05978.16 KKK11805.1 - 0.044 13.5 7.0 0.17 11.6 0.1 2.6 2 1 0 2 2 2 0 Ion channel regulatory protein UNC-93 Ribosomal_L7Ae PF01248.26 KKK11806.1 - 6.9e-23 80.2 0.0 8.5e-23 79.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 KKK11806.1 - 0.00038 20.6 0.0 0.00038 20.6 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 PELOTA_1 PF15608.6 KKK11806.1 - 0.0008 19.2 0.0 0.0011 18.8 0.0 1.2 1 0 0 1 1 1 1 PELOTA RNA binding domain Abhydrolase_4 PF08386.10 KKK11807.1 - 1.9e-19 69.7 0.0 1.1e-18 67.2 0.0 2.2 2 0 0 2 2 2 1 TAP-like protein Abhydrolase_1 PF00561.20 KKK11807.1 - 2.3e-19 70.0 0.0 7.6e-19 68.4 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold FAD_binding_3 PF01494.19 KKK11808.1 - 9.2e-21 74.5 0.0 2.3e-20 73.2 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 KKK11808.1 - 0.056 12.7 0.8 4.4 6.4 0.2 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KKK11808.1 - 0.12 12.6 0.2 0.44 10.8 0.2 1.9 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Glyco_hydro_10 PF00331.20 KKK11809.1 - 4.9e-86 288.8 0.3 5.5e-86 288.6 0.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Fungal_trans PF04082.18 KKK11810.1 - 5.3e-12 45.3 0.7 1.1e-11 44.2 0.7 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.6 KKK11810.1 - 7e-09 35.7 6.5 5.4e-08 32.9 1.9 3.4 3 1 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.26 KKK11810.1 - 4.2e-08 33.2 7.6 0.00024 21.4 2.0 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type Zn_clus PF00172.18 KKK11810.1 - 1.6e-06 28.1 9.2 1.6e-06 28.1 9.2 2.4 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_4 PF13894.6 KKK11810.1 - 2.6e-06 27.8 6.7 0.032 15.0 1.3 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KKK11810.1 - 0.27 11.3 6.7 0.32 11.0 0.3 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger Cupin_2 PF07883.11 KKK11811.1 - 1.6e-09 37.4 0.0 2.2e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.12 KKK11811.1 - 0.012 15.2 0.0 0.02 14.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Cupin_1 PF00190.22 KKK11811.1 - 0.016 14.8 0.0 0.024 14.3 0.0 1.3 1 0 0 1 1 1 0 Cupin Big_1 PF02369.16 KKK11811.1 - 0.095 12.7 0.1 0.2 11.7 0.0 1.6 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 1) Aldedh PF00171.22 KKK11812.1 - 5.3e-128 427.4 0.0 7.6e-128 426.9 0.0 1.2 1 0 0 1 1 1 1 Aldehyde dehydrogenase family adh_short PF00106.25 KKK11812.1 - 2.9e-39 134.6 0.0 6.7e-39 133.4 0.0 1.7 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KKK11812.1 - 1.7e-37 129.3 0.1 3.6e-37 128.2 0.1 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KKK11812.1 - 4.7e-09 36.4 0.5 1.1e-08 35.2 0.5 1.5 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KKK11812.1 - 0.00048 19.7 0.1 0.0064 16.0 0.0 2.5 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family DUF1487 PF07368.11 KKK11812.1 - 0.0024 17.4 0.1 0.012 15.0 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1487) LDcluster4 PF18306.1 KKK11812.1 - 0.065 12.8 0.1 0.16 11.6 0.1 1.7 1 0 0 1 1 1 0 SLOG cluster4 family DUF4491 PF14898.6 KKK11812.1 - 0.12 12.8 0.0 0.31 11.5 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4491) UNC-50 PF05216.13 KKK11812.1 - 0.13 11.8 0.0 0.22 11.0 0.0 1.2 1 0 0 1 1 1 0 UNC-50 family MFS_1 PF07690.16 KKK11813.1 - 2.7e-24 85.8 35.5 6.9e-24 84.4 35.4 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KKK11813.1 - 4.8e-09 35.6 10.1 4.8e-09 35.6 10.1 2.9 2 1 0 3 3 3 2 Sugar (and other) transporter DUF5336 PF17270.2 KKK11814.1 - 7.2 6.2 7.1 3.2 7.3 3.1 2.3 2 1 0 2 2 2 0 Family of unknown function (DUF5336) Ribosomal_L5_C PF00673.21 KKK11815.1 - 1e-21 76.9 0.0 1.5e-21 76.4 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 KKK11815.1 - 2.7e-20 72.4 0.0 7.5e-20 71.0 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L5 LSM PF01423.22 KKK11816.1 - 2.1e-19 68.9 0.1 2.6e-19 68.7 0.1 1.1 1 0 0 1 1 1 1 LSM domain MPC PF03650.13 KKK11817.1 - 2.4e-36 124.2 0.0 2.9e-36 124.0 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers Phage_Coat_B PF05356.11 KKK11817.1 - 0.074 13.0 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Phage Coat protein B Aa_trans PF01490.18 KKK11818.1 - 1.1e-83 281.2 30.7 1.5e-83 280.8 30.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease PF00324.21 KKK11819.1 - 3.6e-59 200.6 32.7 4.6e-59 200.3 32.7 1.1 1 0 0 1 1 1 1 Amino acid permease SLC12 PF03522.15 KKK11819.1 - 1.3e-21 77.1 0.8 1.9e-07 30.5 0.1 3.3 3 0 0 3 3 3 3 Solute carrier family 12 AA_permease_2 PF13520.6 KKK11819.1 - 8.4e-19 67.7 39.3 1.1e-18 67.3 39.3 1.1 1 0 0 1 1 1 1 Amino acid permease Histidinol_dh PF00815.20 KKK11820.1 - 1.4e-123 412.9 0.3 9.9e-98 327.8 0.1 2.0 1 1 1 2 2 2 2 Histidinol dehydrogenase FAD_binding_3 PF01494.19 KKK11821.1 - 1.2e-24 87.3 0.0 1.7e-24 86.8 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KKK11821.1 - 4e-08 32.8 1.0 5.9e-05 22.4 0.4 2.1 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KKK11821.1 - 1.7e-07 31.4 0.6 4.3e-07 30.1 0.6 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain ADC PF06314.11 KKK11821.1 - 3e-07 30.3 0.0 8e-07 28.9 0.0 1.8 1 1 0 1 1 1 1 Acetoacetate decarboxylase (ADC) FAD_binding_2 PF00890.24 KKK11821.1 - 1e-05 24.8 0.5 1.7e-05 24.1 0.5 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KKK11821.1 - 0.00018 21.2 2.5 0.00037 20.2 1.4 1.9 1 1 0 2 2 2 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 KKK11821.1 - 0.0003 19.8 0.5 0.011 14.6 0.2 2.6 3 0 0 3 3 3 1 Tryptophan halogenase Pyr_redox PF00070.27 KKK11821.1 - 0.00052 20.5 0.3 0.0048 17.4 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KKK11821.1 - 0.0007 19.1 0.3 0.0012 18.2 0.3 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 KKK11821.1 - 0.0013 18.0 2.2 0.0025 17.1 1.7 1.6 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 KKK11821.1 - 0.0018 17.4 0.1 0.0028 16.8 0.1 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.14 KKK11821.1 - 0.0043 15.8 0.1 0.008 14.9 0.1 1.4 1 0 0 1 1 1 1 HI0933-like protein Amino_oxidase PF01593.24 KKK11821.1 - 0.0088 15.4 0.3 0.65 9.2 0.0 2.3 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.6 KKK11821.1 - 0.019 14.2 0.0 0.047 12.9 0.0 1.6 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KKK11821.1 - 0.077 12.2 0.1 0.13 11.4 0.1 1.3 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.6 KKK11821.1 - 0.23 11.5 0.8 1.1 9.3 0.8 2.1 1 1 0 1 1 1 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 KKK11821.1 - 0.51 9.3 1.3 3.8 6.5 0.1 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein DUF2591 PF10765.9 KKK11824.1 - 0.17 12.2 0.1 0.27 11.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2591) NDK PF00334.19 KKK11846.1 - 2.2e-18 66.6 0.0 2.5e-18 66.4 0.0 1.1 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Tfb2 PF03849.14 KKK11874.1 - 3.9e-136 453.7 0.0 5.5e-136 453.2 0.0 1.2 1 0 0 1 1 1 1 Transcription factor Tfb2 Tfb2_C PF18307.1 KKK11874.1 - 2.5e-24 85.4 0.2 5.1e-24 84.5 0.2 1.5 1 0 0 1 1 1 1 Transcription factor Tfb2 (p52) C-terminal domain Helicase_C_3 PF13625.6 KKK11874.1 - 2.4e-05 24.5 0.0 7.4e-05 22.9 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain NicO PF03824.16 KKK11875.1 - 0.29 10.5 3.9 0.42 9.9 3.9 1.2 1 0 0 1 1 1 0 High-affinity nickel-transport protein PhzC-PhzF PF02567.16 KKK11876.1 - 8.9e-13 48.3 0.1 8.6e-09 35.3 0.0 2.2 2 0 0 2 2 2 2 Phenazine biosynthesis-like protein TIMELESS_C PF05029.13 KKK11877.1 - 6.9e-87 292.9 35.1 2.9e-64 218.2 0.0 4.2 2 1 2 4 4 4 4 Timeless protein C terminal region TIMELESS PF04821.14 KKK11877.1 - 9.8e-87 290.7 0.0 9.8e-87 290.7 0.0 1.7 2 0 0 2 2 2 1 Timeless protein 3HCDH_N PF02737.18 KKK11878.1 - 1.4e-51 174.9 1.0 2e-51 174.4 1.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 KKK11878.1 - 7.9e-34 116.2 0.0 2e-33 114.8 0.0 1.7 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 KKK11878.1 - 0.00057 20.1 0.2 0.0014 18.9 0.2 1.6 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Sacchrp_dh_NADP PF03435.18 KKK11878.1 - 0.0095 16.2 0.4 0.02 15.2 0.4 1.6 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Pyr_redox_2 PF07992.14 KKK11878.1 - 0.017 14.4 0.0 0.022 14.0 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KKK11878.1 - 0.017 14.7 0.1 0.024 14.2 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase UDPG_MGDP_dh_N PF03721.14 KKK11878.1 - 0.03 13.9 0.0 0.044 13.4 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.19 KKK11878.1 - 0.12 11.7 0.2 0.32 10.3 0.1 1.7 1 1 1 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Actin PF00022.19 KKK11879.1 - 1.4e-107 359.8 0.0 9.1e-107 357.2 0.0 2.0 1 1 0 1 1 1 1 Actin efThoc1 PF11957.8 KKK11881.1 - 2.1e-151 505.0 5.7 2.8e-151 504.5 5.7 1.1 1 0 0 1 1 1 1 THO complex subunit 1 transcription elongation factor Homeodomain PF00046.29 KKK11882.1 - 1.3e-16 60.2 4.1 2.4e-16 59.3 4.1 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KKK11882.1 - 0.23 11.4 0.2 0.23 11.4 0.2 1.9 2 0 0 2 2 2 0 Homeobox KN domain 4HBT PF03061.22 KKK11884.1 - 8.3e-15 54.9 0.1 1.2e-14 54.4 0.1 1.2 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.6 KKK11884.1 - 0.0067 16.6 0.0 0.0098 16.0 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4442) 4HBT_3 PF13622.6 KKK11884.1 - 0.071 13.4 0.0 0.073 13.3 0.0 1.1 1 0 0 1 1 1 0 Thioesterase-like superfamily Aquarius_N PF16399.5 KKK11885.1 - 0 1103.0 0.0 0 1102.6 0.0 1.1 1 0 0 1 1 1 1 Intron-binding protein aquarius N-terminus AAA_12 PF13087.6 KKK11885.1 - 4.4e-27 95.0 0.0 7.8e-27 94.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KKK11885.1 - 1.5e-21 77.4 0.0 4.2e-21 75.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KKK11885.1 - 5.8e-07 29.4 0.0 0.00034 20.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain ResIII PF04851.15 KKK11885.1 - 4.1e-06 26.9 0.0 9.6e-06 25.7 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 KKK11885.1 - 1.3e-05 25.5 0.0 3.7e-05 24.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 KKK11885.1 - 0.00031 20.6 0.1 0.11 12.2 0.0 3.4 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase DnaB_C PF03796.15 KKK11885.1 - 0.00032 20.1 0.2 0.013 14.8 0.0 2.9 3 0 0 3 3 3 1 DnaB-like helicase C terminal domain AAA_16 PF13191.6 KKK11885.1 - 0.00093 19.6 0.2 0.0059 17.0 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 KKK11885.1 - 0.0033 17.9 0.0 0.011 16.2 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) UvrD_C_2 PF13538.6 KKK11885.1 - 0.0035 17.1 1.1 0.022 14.6 0.5 2.3 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_22 PF13401.6 KKK11885.1 - 0.013 15.8 0.4 0.15 12.3 0.1 2.7 1 1 1 2 2 2 0 AAA domain DUF2075 PF09848.9 KKK11885.1 - 0.014 14.7 1.0 0.024 13.9 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) UvrD-helicase PF00580.21 KKK11885.1 - 0.034 13.7 0.0 0.11 12.0 0.0 1.9 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain DEAD PF00270.29 KKK11885.1 - 0.04 13.7 0.0 0.15 11.9 0.0 1.9 2 0 0 2 2 2 0 DEAD/DEAH box helicase Adeno_IVa2 PF02456.15 KKK11885.1 - 0.067 12.0 0.1 0.18 10.6 0.0 1.7 2 0 0 2 2 2 0 Adenovirus IVa2 protein AAA_5 PF07728.14 KKK11885.1 - 0.11 12.5 0.0 0.28 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ATPase_2 PF01637.18 KKK11885.1 - 0.11 12.4 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_25 PF13481.6 KKK11885.1 - 0.19 11.3 0.0 0.48 10.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 KKK11885.1 - 0.2 10.7 0.0 0.35 9.9 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 RRM_1 PF00076.22 KKK11886.1 - 1.2e-15 57.1 0.0 1.7e-15 56.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RINGv PF12906.7 KKK11887.1 - 4.4e-15 55.5 9.3 8.5e-15 54.6 9.3 1.5 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.6 KKK11887.1 - 0.0047 17.2 8.8 0.01 16.2 8.8 1.6 1 0 0 1 1 1 1 Ring finger domain S1FA PF04689.13 KKK11887.1 - 0.22 11.7 0.1 0.94 9.7 0.1 2.1 1 0 0 1 1 1 0 DNA binding protein S1FA DEAD PF00270.29 KKK11888.1 - 2.5e-28 99.0 0.0 1.5e-26 93.2 0.0 2.6 2 1 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KKK11888.1 - 1.2e-12 48.1 0.9 2.3e-11 44.0 0.3 2.9 2 1 1 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KKK11888.1 - 0.00023 21.2 0.0 0.0029 17.6 0.0 2.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Pex16 PF08610.10 KKK11888.1 - 0.058 12.5 0.1 0.13 11.4 0.1 1.5 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) PH PF00169.29 KKK11889.1 - 2.3e-08 34.5 0.0 7.8e-08 32.8 0.0 1.8 1 1 0 1 1 1 1 PH domain Anillin PF08174.11 KKK11889.1 - 1.2e-07 32.2 0.0 2.7e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 Cell division protein anillin TFIIS_C PF01096.18 KKK11890.1 - 1.4e-14 53.6 3.0 1.4e-14 53.6 3.0 3.0 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 KKK11890.1 - 2.2e-11 43.4 1.7 2.2e-11 43.4 1.7 3.0 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit GFA PF04828.14 KKK11890.1 - 0.021 15.2 10.4 0.18 12.2 0.8 2.6 1 1 2 3 3 3 0 Glutathione-dependent formaldehyde-activating enzyme Lar_restr_allev PF14354.6 KKK11890.1 - 0.03 14.7 2.6 0.03 14.7 2.6 2.3 2 1 0 2 2 2 0 Restriction alleviation protein Lar DZR PF12773.7 KKK11890.1 - 0.074 13.1 12.1 0.95 9.5 1.6 2.6 2 2 0 2 2 2 0 Double zinc ribbon Nudix_N_2 PF14803.6 KKK11890.1 - 0.15 12.0 9.9 4 7.4 1.8 3.4 3 0 0 3 3 3 0 Nudix N-terminal Zn_Tnp_IS1595 PF12760.7 KKK11890.1 - 0.32 11.0 12.5 1.7 8.7 4.8 2.7 2 1 0 2 2 2 0 Transposase zinc-ribbon domain DUF3268 PF11672.8 KKK11890.1 - 9.5 6.6 9.7 1.7 9.0 2.4 2.3 2 1 0 2 2 2 0 zinc-finger-containing domain SET PF00856.28 KKK11891.1 - 5.6e-10 39.9 0.9 1e-08 35.8 0.1 3.1 2 2 0 2 2 2 1 SET domain Rotamase PF00639.21 KKK11893.1 - 4.1e-23 82.2 0.0 5.3e-23 81.8 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 KKK11893.1 - 5.2e-16 59.2 0.0 6.6e-16 58.9 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 KKK11893.1 - 0.0002 22.2 0.0 0.00024 21.9 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain MAM PF00629.23 KKK11893.1 - 0.01 15.7 0.0 0.012 15.5 0.0 1.1 1 0 0 1 1 1 0 MAM domain, meprin/A5/mu Ribosomal_L14 PF00238.19 KKK11894.1 - 3.7e-48 162.6 3.2 4.1e-48 162.5 3.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Phage_antitermQ PF06530.12 KKK11894.1 - 0.07 13.0 0.1 0.13 12.2 0.1 1.4 1 0 0 1 1 1 0 Phage antitermination protein Q ACPS PF01648.20 KKK11895.1 - 7.6e-10 38.9 0.0 1.9e-09 37.7 0.0 1.7 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily SNO PF01174.19 KKK11896.1 - 5.9e-53 179.5 0.0 6.3e-42 143.6 0.0 2.0 1 1 1 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.14 KKK11896.1 - 1.4e-07 31.4 0.0 2.9e-06 27.0 0.0 2.1 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.28 KKK11896.1 - 0.0068 16.2 0.0 0.019 14.8 0.0 1.6 1 1 0 1 1 1 1 Glutamine amidotransferase class-I DJ-1_PfpI PF01965.24 KKK11896.1 - 0.034 13.9 0.0 0.073 12.9 0.0 1.5 1 0 0 1 1 1 0 DJ-1/PfpI family Acyltransferase PF01553.21 KKK11897.1 - 1.8e-32 111.8 0.0 2.7e-32 111.2 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase TPR_1 PF00515.28 KKK11898.1 - 9.5e-38 126.5 22.6 2e-07 30.5 0.1 9.8 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_2 PF07719.17 KKK11898.1 - 3.9e-35 117.1 21.8 6.2e-05 22.8 0.0 10.4 10 0 0 10 10 10 7 Tetratricopeptide repeat ANAPC3 PF12895.7 KKK11898.1 - 2.1e-28 98.4 18.3 1.2e-23 83.1 0.4 4.7 4 1 1 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 KKK11898.1 - 2.2e-25 88.0 5.6 7.4e-06 25.5 0.7 8.9 7 2 2 9 9 9 7 TPR repeat TPR_8 PF13181.6 KKK11898.1 - 5e-22 76.2 10.9 0.0081 16.3 0.0 9.9 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_19 PF14559.6 KKK11898.1 - 7.4e-22 77.6 18.3 3.5e-07 30.6 1.0 7.8 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_12 PF13424.6 KKK11898.1 - 2.8e-19 69.2 11.8 0.0064 16.8 0.3 7.5 5 1 2 7 7 7 6 Tetratricopeptide repeat TPR_16 PF13432.6 KKK11898.1 - 2.7e-18 66.3 19.5 1.7e-05 25.3 0.2 7.9 7 1 1 8 8 8 5 Tetratricopeptide repeat TPR_14 PF13428.6 KKK11898.1 - 2.6e-16 58.9 11.2 0.14 13.1 0.0 9.4 6 1 3 9 9 9 3 Tetratricopeptide repeat TPR_17 PF13431.6 KKK11898.1 - 6.1e-10 38.8 15.7 0.27 11.7 0.0 8.2 9 1 1 10 10 9 4 Tetratricopeptide repeat TPR_7 PF13176.6 KKK11898.1 - 3.3e-08 33.0 6.8 0.32 11.1 0.0 7.0 7 1 0 7 7 6 2 Tetratricopeptide repeat TPR_6 PF13174.6 KKK11898.1 - 3.9e-05 24.0 16.9 7.9 7.3 0.2 9.0 11 0 0 11 11 9 1 Tetratricopeptide repeat TPR_9 PF13371.6 KKK11898.1 - 0.00028 21.0 4.6 3.4 7.9 0.3 5.4 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_10 PF13374.6 KKK11898.1 - 0.0026 17.6 2.5 95 3.1 0.2 5.8 6 0 0 6 6 6 0 Tetratricopeptide repeat DUF410 PF04190.13 KKK11898.1 - 0.054 13.3 1.5 0.65 9.8 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF410) ChAPs PF09295.10 KKK11898.1 - 0.1 11.6 1.0 8.3 5.3 0.0 2.9 3 0 0 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) MIT PF04212.18 KKK11898.1 - 1.4 9.1 6.2 27 4.9 0.5 4.8 5 0 0 5 5 5 0 MIT (microtubule interacting and transport) domain TMEM208_SND2 PF05620.11 KKK11899.1 - 2.6e-54 183.5 0.0 2.9e-54 183.3 0.0 1.0 1 0 0 1 1 1 1 SRP-independent targeting protein 2/TMEM208 HeLo PF14479.6 KKK11901.1 - 1.3e-07 31.7 0.3 0.0004 20.3 0.1 2.3 1 1 1 2 2 2 2 Prion-inhibition and propagation Pkinase_Tyr PF07714.17 KKK11901.1 - 0.14 11.4 0.0 0.7 9.1 0.0 1.9 1 1 0 1 1 1 0 Protein tyrosine kinase Ntox3 PF15536.6 KKK11901.1 - 0.15 12.1 0.0 0.3 11.1 0.0 1.4 1 0 0 1 1 1 0 Bacterial toxin 3 Astro_capsid_p PF12226.8 KKK11901.1 - 3.3 6.8 8.3 5.3 6.1 8.3 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein DUF3395 PF11875.8 KKK11904.1 - 3.2e-43 147.3 0.4 3.2e-43 147.3 0.4 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3395) RNase_H2_suC PF08615.11 KKK11904.1 - 0.043 14.0 0.3 1.4 9.1 0.0 2.3 2 0 0 2 2 2 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) CDC45 PF02724.14 KKK11904.1 - 3.1 6.0 9.7 0.41 8.9 1.4 2.2 2 0 0 2 2 2 0 CDC45-like protein eIF-3c_N PF05470.12 KKK11904.1 - 4.9 5.3 6.3 19 3.4 2.6 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Septin PF00735.18 KKK11905.1 - 5e-37 127.7 0.1 5e-37 127.7 0.1 1.6 2 0 0 2 2 2 1 Septin FOXP-CC PF16159.5 KKK11905.1 - 0.0095 16.6 0.9 0.0095 16.6 0.9 1.9 2 0 0 2 2 2 1 FOXP coiled-coil domain FUSC PF04632.12 KKK11905.1 - 0.24 9.9 2.8 0.28 9.7 2.8 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Casc1_N PF15927.5 KKK11905.1 - 0.57 9.8 11.9 0.1 12.3 8.1 1.5 2 0 0 2 2 2 0 Cancer susceptibility candidate 1 N-terminus Myc-LZ PF02344.15 KKK11905.1 - 1.1 9.4 5.6 2.1 8.5 0.4 2.7 2 0 0 2 2 2 0 Myc leucine zipper domain WD40 PF00400.32 KKK11906.1 - 9.4e-21 73.8 12.0 0.00036 21.3 0.4 7.3 8 0 0 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKK11906.1 - 7.3e-11 42.2 0.3 0.018 15.3 0.0 4.8 3 1 3 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain PQQ PF01011.21 KKK11906.1 - 0.00034 20.4 0.2 0.0082 16.0 0.0 3.0 3 0 0 3 3 3 1 PQQ enzyme repeat VID27 PF08553.10 KKK11906.1 - 0.0073 15.4 0.0 0.011 14.8 0.0 1.2 1 0 0 1 1 1 1 VID27 C-terminal WD40-like domain PQQ_3 PF13570.6 KKK11906.1 - 0.83 10.2 4.8 2.6 8.6 0.1 3.7 4 0 0 4 4 4 0 PQQ-like domain ACT_7 PF13840.6 KKK11907.1 - 6.2e-24 83.6 0.3 5.6e-16 58.1 0.0 3.5 3 0 0 3 3 3 3 ACT domain LisH_TPL PF17814.1 KKK11907.1 - 0.0038 16.8 0.3 0.012 15.3 0.3 1.8 1 0 0 1 1 1 1 LisH-like dimerisation domain SKIP_SNW PF02731.15 KKK11908.1 - 1.1e-72 242.9 4.9 1.1e-72 242.9 4.9 2.2 2 0 0 2 2 2 1 SKIP/SNW domain Glucosamine_iso PF01182.20 KKK11925.1 - 1.9e-20 73.7 0.0 3.3e-20 73.0 0.0 1.3 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Glyco_hydro_3 PF00933.21 KKK11926.1 - 1.3e-67 228.4 0.0 1.8e-67 228.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Acetyltransf_1 PF00583.25 KKK11926.1 - 4.1e-05 23.8 0.0 0.00012 22.3 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Glyco_hydro_3_C PF01915.22 KKK11926.1 - 0.0025 17.8 0.0 0.005 16.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain NDT80_PhoG PF05224.12 KKK11927.1 - 1.8e-37 129.4 0.1 4.8e-37 128.0 0.1 1.8 1 1 0 1 1 1 1 NDT80 / PhoG like DNA-binding family Herpes_LMP2 PF07415.11 KKK11927.1 - 1.3 7.7 5.2 1.9 7.2 5.2 1.1 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein Metallophos PF00149.28 KKK11936.1 - 9e-40 137.4 0.1 1.3e-39 136.9 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase LRR_4 PF12799.7 KKK11937.1 - 1.2e-11 44.7 4.6 0.0023 18.3 0.1 4.2 4 0 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KKK11937.1 - 9.5e-11 41.3 10.7 3e-06 26.9 0.7 4.0 2 1 2 4 4 4 3 Leucine rich repeat LRR_9 PF14580.6 KKK11937.1 - 0.0023 17.5 0.9 0.038 13.5 0.7 2.3 1 1 1 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.33 KKK11937.1 - 0.11 13.2 8.5 24 6.0 0.2 5.6 5 1 0 5 5 5 0 Leucine Rich Repeat LRR_6 PF13516.6 KKK11937.1 - 0.66 10.2 10.8 1.7 8.9 0.5 4.9 6 0 0 6 6 6 0 Leucine Rich repeat Fungal_trans_2 PF11951.8 KKK11938.1 - 6.6e-05 21.9 1.7 0.00011 21.1 0.2 1.9 2 1 0 2 2 2 1 Fungal specific transcription factor domain RdRP PF05183.12 KKK11939.1 - 2.1e-183 611.1 0.0 2.7e-183 610.8 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase RRM_1 PF00076.22 KKK11939.1 - 0.021 14.6 0.0 0.056 13.3 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DNA_binding_2 PF13724.6 KKK11939.1 - 0.1 13.0 0.2 0.28 11.6 0.0 1.8 2 0 0 2 2 2 0 DNA-binding domain TPR_19 PF14559.6 KKK11940.1 - 7.7e-19 68.0 17.9 5.7e-08 33.2 0.0 8.2 6 2 3 9 9 9 3 Tetratricopeptide repeat TPR_2 PF07719.17 KKK11940.1 - 7.3e-12 44.4 23.7 0.0073 16.3 0.0 9.1 10 0 0 10 10 9 4 Tetratricopeptide repeat TPR_17 PF13431.6 KKK11940.1 - 7.6e-12 44.8 2.0 0.014 15.7 0.0 6.6 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_11 PF13414.6 KKK11940.1 - 5e-11 42.1 10.7 0.01 15.5 0.0 6.8 6 1 1 7 7 7 3 TPR repeat TPR_14 PF13428.6 KKK11940.1 - 1.2e-09 38.2 26.6 0.00088 19.9 1.2 9.6 10 1 1 11 11 9 2 Tetratricopeptide repeat TPR_1 PF00515.28 KKK11940.1 - 1.7e-09 37.1 17.9 0.022 14.6 0.0 9.0 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_16 PF13432.6 KKK11940.1 - 1.8e-09 38.1 16.3 3.2e-05 24.5 0.0 5.9 6 0 0 6 6 6 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KKK11940.1 - 8.2e-09 35.6 13.1 0.053 13.8 0.0 6.9 7 1 0 7 7 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 KKK11940.1 - 3.4e-08 33.0 16.0 1.5 9.1 0.0 8.4 10 0 0 10 10 8 2 Tetratricopeptide repeat TPR_8 PF13181.6 KKK11940.1 - 7.5e-07 28.9 14.4 1.3 9.4 0.0 8.2 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_12 PF13424.6 KKK11940.1 - 3.3e-06 27.3 12.3 0.041 14.2 0.1 6.4 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.6 KKK11940.1 - 0.011 16.3 8.0 50 4.8 0.2 7.0 8 0 0 8 8 6 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 KKK11940.1 - 0.034 14.6 1.8 9.9 6.6 0.0 2.9 3 0 0 3 3 2 0 Alkyl sulfatase dimerisation TPR_9 PF13371.6 KKK11940.1 - 0.041 14.0 0.3 0.041 14.0 0.3 4.5 4 1 2 6 6 5 0 Tetratricopeptide repeat CDC45 PF02724.14 KKK11940.1 - 0.26 9.6 3.0 0.45 8.7 3.0 1.3 1 0 0 1 1 1 0 CDC45-like protein TPR_20 PF14561.6 KKK11940.1 - 0.63 10.4 13.1 19 5.6 0.0 5.5 5 1 1 6 6 5 0 Tetratricopeptide repeat NARP1 PF12569.8 KKK11940.1 - 0.71 8.7 6.7 8.5 5.2 0.1 3.3 2 2 1 3 3 3 0 NMDA receptor-regulated protein 1 BTAD PF03704.17 KKK11940.1 - 0.88 10.0 8.1 0.36 11.2 1.5 3.5 3 1 2 5 5 5 0 Bacterial transcriptional activator domain SAM_2 PF07647.17 KKK11941.1 - 5.5e-09 36.0 0.1 1.1e-08 35.1 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KKK11941.1 - 0.00016 22.0 0.1 0.00039 20.8 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DUF4508 PF14969.6 KKK11941.1 - 0.1 12.9 0.2 0.25 11.6 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4508) DHC_N1 PF08385.12 KKK11941.1 - 0.14 10.8 1.6 0.29 9.7 1.6 1.5 1 1 0 1 1 1 0 Dynein heavy chain, N-terminal region 1 Pyr_redox_2 PF07992.14 KKK11942.1 - 2.3e-23 82.9 0.0 3.3e-23 82.4 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KKK11942.1 - 4e-11 43.3 0.2 1.2e-08 35.3 0.0 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KKK11942.1 - 0.0004 19.6 0.0 0.00064 19.0 0.0 1.2 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 KKK11942.1 - 0.0017 18.0 1.6 0.095 12.3 0.4 3.2 4 0 0 4 4 4 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KKK11942.1 - 0.0032 16.6 1.8 0.041 12.9 0.1 2.6 2 1 1 3 3 3 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 KKK11942.1 - 0.0057 15.9 0.1 2.1 7.5 0.3 3.0 2 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KKK11942.1 - 0.036 14.0 0.3 34 4.4 0.1 3.7 3 1 1 4 4 4 0 FAD-NAD(P)-binding Amino_oxidase PF01593.24 KKK11942.1 - 0.059 12.7 0.1 0.16 11.2 0.0 1.7 2 1 1 3 3 3 0 Flavin containing amine oxidoreductase GIDA PF01134.22 KKK11942.1 - 0.074 12.1 0.5 14 4.6 0.0 3.1 3 0 0 3 3 3 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 KKK11942.1 - 0.098 11.9 0.0 7.1 5.9 0.0 2.3 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 KKK11942.1 - 0.12 11.6 0.4 0.3 10.3 0.1 1.8 2 0 0 2 2 2 0 Thi4 family NAD_binding_8 PF13450.6 KKK11942.1 - 0.19 12.0 0.6 6.3 7.1 0.0 2.5 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain DUF3336 PF11815.8 KKK11944.1 - 2e-47 160.4 2.4 2e-47 160.4 2.4 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3336) Patatin PF01734.22 KKK11944.1 - 4e-18 66.3 0.3 2.1e-16 60.7 0.1 3.2 2 1 0 2 2 2 1 Patatin-like phospholipase AAA_lid_2 PF17863.1 KKK11944.1 - 0.16 11.8 0.0 0.39 10.6 0.0 1.6 1 0 0 1 1 1 0 AAA lid domain DUF2457 PF10446.9 KKK11945.1 - 4.3e-144 481.2 37.7 4.3e-144 481.2 37.7 3.4 3 1 0 3 3 3 1 Protein of unknown function (DUF2457) Arf PF00025.21 KKK11945.1 - 1.1e-62 210.6 0.0 1.6e-62 210.0 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 KKK11945.1 - 5.7e-09 35.6 0.0 4.6e-06 26.0 0.0 2.4 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 KKK11945.1 - 5.8e-07 29.1 0.0 1.1e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KKK11945.1 - 9.7e-06 25.6 0.0 1.8e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 KKK11945.1 - 1e-05 25.7 0.0 3.3e-05 24.1 0.0 1.9 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KKK11945.1 - 0.00084 19.0 0.0 0.0015 18.1 0.0 1.4 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 KKK11945.1 - 0.0017 17.7 0.0 0.0027 17.1 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Fungal_trans_2 PF11951.8 KKK11952.1 - 1.6e-46 158.9 0.0 2.3e-46 158.4 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK11952.1 - 0.087 13.0 3.2 0.2 11.8 3.2 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 KKK11953.1 - 1.4e-25 90.0 39.2 1.4e-25 90.0 39.2 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KKK11953.1 - 1.1e-08 34.4 25.5 2.4e-08 33.3 25.5 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 KKK11953.1 - 0.04 12.3 10.6 0.0056 15.2 5.5 1.9 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) P5CR_dimer PF14748.6 KKK11953.1 - 0.078 13.2 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 Pyrroline-5-carboxylate reductase dimerisation ssDBP_DBD PF18361.1 KKK11956.1 - 0.18 11.9 0.1 0.29 11.3 0.1 1.3 1 0 0 1 1 1 0 Single stranded DNA-binding protein ss DNA binding domain Lin-8 PF03353.15 KKK11956.1 - 3.8 7.0 12.6 4.5 6.7 12.6 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Fer4 PF00037.27 KKK11958.1 - 3.9e-14 51.8 15.9 3.6e-08 32.9 4.1 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 KKK11958.1 - 1.3e-12 48.1 10.4 2e-12 47.5 10.4 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 KKK11958.1 - 4.1e-11 43.6 7.8 1.7e-05 25.6 0.5 2.3 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_21 PF14697.6 KKK11958.1 - 4.5e-10 39.5 4.2 0.00011 22.2 0.4 2.1 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 KKK11958.1 - 8.1e-10 38.7 21.8 7.5e-07 29.2 12.4 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 KKK11958.1 - 1.5e-09 37.9 21.0 8.1e-08 32.3 10.8 1.7 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_8 PF13183.6 KKK11958.1 - 1.1e-08 35.4 2.3 0.00027 21.3 0.1 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 KKK11958.1 - 1.7e-06 27.9 17.5 0.00038 20.4 5.4 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_2 PF12797.7 KKK11958.1 - 4.9e-06 26.3 12.5 0.01 15.9 2.0 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 KKK11958.1 - 2.2e-05 24.6 11.4 0.00029 21.1 1.8 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 KKK11958.1 - 0.00012 22.5 12.0 0.019 15.5 1.9 2.3 1 1 2 3 3 3 3 4Fe-4S dicluster domain c-SKI_SMAD_bind PF08782.10 KKK11958.1 - 0.018 15.3 6.1 0.98 9.7 0.3 2.2 1 1 1 2 2 2 0 c-SKI Smad4 binding domain Fer4_13 PF13370.6 KKK11958.1 - 0.051 14.1 15.4 0.72 10.4 4.3 2.6 2 1 1 3 3 3 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_18 PF13746.6 KKK11958.1 - 0.064 13.5 9.3 1.3 9.2 1.5 2.2 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_3 PF12798.7 KKK11958.1 - 0.066 14.2 15.7 0.12 13.4 3.5 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain ETF_QO PF05187.13 KKK11958.1 - 0.088 12.9 5.7 0.44 10.7 0.5 2.2 1 1 1 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Fer4_22 PF17179.4 KKK11958.1 - 0.51 11.2 11.9 1.5 9.7 1.6 2.2 1 1 1 2 2 2 0 4Fe-4S dicluster domain PP-binding PF00550.25 KKK11959.1 - 1.7e-10 41.1 0.1 2.3e-10 40.6 0.1 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 KKK11959.1 - 5.1e-06 26.6 0.1 6.3e-06 26.3 0.1 1.1 1 0 0 1 1 1 1 Acyl-carrier SURF6 PF04935.12 KKK11960.1 - 2.6e-49 167.7 27.0 2.6e-49 167.7 27.0 4.7 2 1 0 2 2 2 1 Surfeit locus protein 6 RRP14 PF15459.6 KKK11960.1 - 8.5e-19 67.9 0.9 8.5e-19 67.9 0.9 8.0 6 2 1 7 7 7 1 60S ribosome biogenesis protein Rrp14 GTP_EFTU PF00009.27 KKK11961.1 - 1.1e-28 100.1 2.9 1.1e-28 100.1 2.9 2.5 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 KKK11961.1 - 2.1e-26 92.1 0.0 5.3e-26 90.8 0.0 1.7 1 0 0 1 1 1 1 Translation-initiation factor 2 IF2_N PF04760.15 KKK11961.1 - 6.5e-11 41.9 0.0 1.7e-10 40.5 0.0 1.8 1 0 0 1 1 1 1 Translation initiation factor IF-2, N-terminal region MMR_HSR1 PF01926.23 KKK11961.1 - 4.7e-09 36.3 0.4 1.8e-08 34.4 0.1 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 KKK11961.1 - 3.5e-05 24.1 4.4 0.078 13.4 0.1 3.0 3 0 0 3 3 3 2 Elongation factor Tu domain 2 Arf PF00025.21 KKK11961.1 - 0.0041 16.6 0.0 0.0074 15.8 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KKK11961.1 - 0.0088 15.5 0.0 0.0088 15.5 0.0 2.1 3 0 0 3 3 3 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 KKK11961.1 - 0.11 12.2 0.1 0.35 10.6 0.1 1.8 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.18 KKK11961.1 - 0.15 11.5 0.0 0.39 10.2 0.0 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B Dynamin_N PF00350.23 KKK11961.1 - 0.8 9.7 3.9 45 4.1 0.0 3.8 3 1 1 4 4 4 0 Dynamin family AAA_23 PF13476.6 KKK11961.1 - 3.5 8.1 6.9 14 6.1 0.0 3.5 4 0 0 4 4 4 0 AAA domain EI24 PF07264.11 KKK11962.1 - 3.3e-18 66.6 13.4 4.1e-18 66.2 13.4 1.1 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) Fer4_14 PF13394.6 KKK11962.1 - 0.032 14.4 0.0 0.055 13.6 0.0 1.3 1 0 0 1 1 1 0 4Fe-4S single cluster domain DC_STAMP PF07782.13 KKK11962.1 - 1.9 8.3 4.6 4.1 7.2 0.1 2.2 2 0 0 2 2 2 0 DC-STAMP-like protein Ribosomal_S2 PF00318.20 KKK11963.1 - 5.9e-68 228.3 0.0 4e-67 225.6 0.0 1.9 1 1 0 1 1 1 1 Ribosomal protein S2 Mito_carr PF00153.27 KKK11964.1 - 7.8e-54 179.6 0.3 1.2e-16 60.4 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Antimicrobial_2 PF08023.12 KKK11964.1 - 0.15 12.6 0.5 0.46 11.1 0.5 1.8 1 0 0 1 1 1 0 Frog antimicrobial peptide BCAS2 PF05700.11 KKK11965.1 - 1e-66 224.6 3.1 1.1e-66 224.4 3.1 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) MFS_1 PF07690.16 KKK11966.1 - 3.8e-40 137.9 35.6 1.7e-38 132.5 33.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KKK11966.1 - 1.1e-12 47.6 11.5 1.1e-12 47.6 11.5 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 KKK11966.1 - 7.3e-08 31.3 5.5 1.1e-07 30.6 5.5 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Zn_clus PF00172.18 KKK11967.1 - 1.7e-08 34.5 10.3 3.3e-08 33.5 10.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KKK11967.1 - 0.089 11.8 0.0 0.14 11.2 0.0 1.4 1 0 0 1 1 1 0 Fungal specific transcription factor domain Ceramidase_alk PF04734.13 KKK11968.1 - 8.3e-211 701.0 0.0 9.6e-211 700.8 0.0 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, N-terminal Ceramidse_alk_C PF17048.5 KKK11968.1 - 1e-55 188.1 0.1 1.6e-55 187.5 0.1 1.3 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, C-terminal Snf7 PF03357.21 KKK11969.1 - 4.6e-35 120.8 24.1 4.6e-35 120.8 24.1 2.0 1 1 1 2 2 2 1 Snf7 DUF3138 PF11336.8 KKK11969.1 - 0.097 11.3 10.1 0.14 10.7 9.1 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3138) DUF4094 PF13334.6 KKK11969.1 - 6.8 7.2 6.7 1.2 9.6 2.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) CRC_subunit PF08624.10 KKK11970.1 - 3.3e-50 170.0 0.1 4.7e-50 169.5 0.1 1.2 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit Spore_III_AF PF09581.10 KKK11970.1 - 0.98 9.4 4.1 1.8 8.6 4.1 1.3 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) Glyco_hydro_18 PF00704.28 KKK11971.1 - 1.1e-19 71.3 2.1 3.4e-19 69.7 2.1 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 DUF4611 PF15387.6 KKK11971.1 - 0.034 14.3 3.1 0.065 13.5 3.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) PBP_sp32 PF07222.12 KKK11971.1 - 0.038 13.4 2.4 0.059 12.8 2.4 1.3 1 0 0 1 1 1 0 Proacrosin binding protein sp32 DUF4834 PF16118.5 KKK11971.1 - 0.04 14.9 0.8 0.04 14.9 0.8 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Sporozoite_P67 PF05642.11 KKK11971.1 - 0.058 11.5 0.6 0.071 11.2 0.6 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen POPLD PF08170.12 KKK11971.1 - 0.17 12.3 2.6 9.2 6.7 0.0 2.3 2 0 0 2 2 2 0 POPLD (NUC188) domain PAXIP1_C PF15364.6 KKK11971.1 - 0.26 11.6 7.9 0.48 10.7 5.8 2.1 2 0 0 2 2 2 0 PAXIP1-associated-protein-1 C term PTIP binding protein DUF1840 PF08895.11 KKK11971.1 - 0.38 11.1 2.5 8.2 6.8 2.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) FAM176 PF14851.6 KKK11971.1 - 0.71 9.5 5.2 1.3 8.7 5.2 1.3 1 0 0 1 1 1 0 FAM176 family PBP1_TM PF14812.6 KKK11971.1 - 0.82 10.1 4.7 1.4 9.4 4.7 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Pox_Ag35 PF03286.14 KKK11971.1 - 1.5 8.6 4.6 2.3 7.9 4.6 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Tim54 PF11711.8 KKK11971.1 - 5.3 5.7 6.4 1 8.1 3.0 1.4 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 NMT1 PF09084.11 KKK11972.1 - 3.7e-05 23.8 0.0 0.00021 21.3 0.0 1.9 1 1 1 2 2 2 1 NMT1/THI5 like NMT1_3 PF16868.5 KKK11972.1 - 0.011 15.2 0.0 0.016 14.7 0.0 1.1 1 0 0 1 1 1 0 NMT1-like family Phosphonate-bd PF12974.7 KKK11972.1 - 0.15 11.7 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 ABC transporter, phosphonate, periplasmic substrate-binding protein Ribosomal_L1 PF00687.21 KKK11973.1 - 3.1e-30 105.5 0.0 4.4e-30 105.0 0.0 1.3 1 1 0 1 1 1 1 Ribosomal protein L1p/L10e family tRNA-synt_1c PF00749.21 KKK11974.1 - 3.9e-105 351.2 0.0 5.4e-105 350.7 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 KKK11974.1 - 1.2e-43 149.1 0.3 2.7e-43 147.9 0.3 1.7 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C_2 PF13410.6 KKK11974.1 - 0.0017 18.3 0.0 0.0044 17.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KKK11974.1 - 0.025 14.7 0.0 0.3 11.3 0.0 2.5 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Glutaredoxin2_C PF04399.13 KKK11974.1 - 0.047 13.5 0.0 0.14 12.0 0.0 1.7 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain GST_C PF00043.25 KKK11974.1 - 0.082 13.1 0.0 0.24 11.7 0.0 1.8 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain tRNA-synt_1e PF01406.19 KKK11974.1 - 0.16 11.3 0.3 0.38 10.1 0.2 1.6 1 1 1 2 2 2 0 tRNA synthetases class I (C) catalytic domain E1-E2_ATPase PF00122.20 KKK11975.1 - 9.5e-35 119.8 5.5 3.6e-32 111.4 4.3 3.3 2 1 0 2 2 2 2 E1-E2 ATPase Hydrolase PF00702.26 KKK11975.1 - 1.3e-18 68.1 0.0 3.6e-18 66.6 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KKK11975.1 - 7.9e-09 35.1 0.0 1.6e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KKK11975.1 - 0.0047 16.7 0.0 0.02 14.7 0.0 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Pyr_redox_2 PF07992.14 KKK11976.1 - 6.4e-16 58.4 0.0 1.8e-08 34.0 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KKK11976.1 - 0.017 14.2 0.8 2.4 7.2 0.1 2.2 1 1 1 2 2 2 0 Glucose inhibited division protein A HI0933_like PF03486.14 KKK11976.1 - 0.021 13.5 0.0 0.041 12.6 0.0 1.4 1 0 0 1 1 1 0 HI0933-like protein K_oxygenase PF13434.6 KKK11976.1 - 0.027 13.6 0.0 0.73 8.9 0.0 2.2 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KKK11976.1 - 0.03 14.5 0.1 0.14 12.4 0.0 2.2 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KKK11976.1 - 0.034 13.2 0.0 0.22 10.6 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain FAD_binding_3 PF01494.19 KKK11976.1 - 0.065 12.5 0.2 0.11 11.7 0.2 1.3 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.17 KKK11976.1 - 0.11 11.8 0.0 0.21 10.8 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.6 KKK11976.1 - 2.5 7.3 3.9 15 4.8 1.9 2.5 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FLILHELTA PF10306.9 KKK11977.1 - 2.5e-31 107.9 0.2 6.1e-31 106.7 0.0 1.7 2 0 0 2 2 2 1 Hypothetical protein FLILHELTA DUF1279 PF06916.13 KKK11977.1 - 0.0016 18.9 0.0 0.0021 18.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) NDK PF00334.19 KKK11978.1 - 4e-54 182.3 0.0 4.5e-54 182.1 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Glyco_hydro_31 PF01055.26 KKK11979.1 - 1.4e-138 462.8 6.5 2e-138 462.3 6.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 KKK11979.1 - 1.8e-25 89.1 0.7 2.8e-24 85.2 0.1 2.6 2 0 0 2 2 2 1 Galactose mutarotase-like DUF5110 PF17137.4 KKK11979.1 - 8.9e-07 29.1 0.1 2.9e-06 27.4 0.1 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF5110) PQ-loop PF04193.14 KKK11980.1 - 7.9e-23 80.0 7.7 1.3e-14 53.7 0.3 3.1 3 0 0 3 3 3 2 PQ loop repeat ER_lumen_recept PF00810.18 KKK11980.1 - 0.0011 19.8 1.1 0.002 18.9 1.1 1.4 1 1 0 1 1 1 1 ER lumen protein retaining receptor Phage_holin_5_2 PF16079.5 KKK11980.1 - 0.78 10.1 4.4 3.7 7.9 0.1 2.7 3 0 0 3 3 3 0 Phage holin family Hol44, in holin superfamily V DUF2070 PF09843.9 KKK11980.1 - 9.6 4.4 7.7 2.1 6.6 1.8 1.9 2 0 0 2 2 2 0 Predicted membrane protein (DUF2070) MTHFR PF02219.17 KKK11981.1 - 3.3e-100 335.1 0.0 4.8e-100 334.6 0.0 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase Protein_K PF12283.8 KKK11981.1 - 0.088 13.0 0.3 0.41 10.9 0.1 2.0 2 0 0 2 2 2 0 Bacteriophage protein K Epimerase PF01370.21 KKK11994.1 - 3.4e-24 85.7 0.0 4.4e-24 85.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KKK11994.1 - 3.4e-22 78.7 0.0 4.5e-22 78.4 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KKK11994.1 - 8.6e-16 58.2 0.0 6.9e-15 55.3 0.0 1.9 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 KKK11994.1 - 1.3e-13 51.3 0.0 2e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 KKK11994.1 - 3.8e-09 36.1 0.0 4.9e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein NmrA PF05368.13 KKK11994.1 - 1.8e-07 31.0 0.0 8.4e-07 28.8 0.0 1.9 2 0 0 2 2 2 1 NmrA-like family Polysacc_synt_2 PF02719.15 KKK11994.1 - 0.00015 21.0 0.0 0.00023 20.4 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.25 KKK11994.1 - 0.0034 16.9 0.0 0.0064 16.0 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KKK11994.1 - 0.085 12.8 0.0 0.14 12.1 0.0 1.4 1 1 0 1 1 1 0 KR domain HlyIII PF03006.20 KKK11995.1 - 9.3e-61 205.4 19.9 1.1e-60 205.1 19.9 1.1 1 0 0 1 1 1 1 Haemolysin-III related Asr PF06392.11 KKK11995.1 - 0.051 14.0 1.0 0.11 12.9 1.0 1.5 1 0 0 1 1 1 0 Acid shock protein repeat Fe-ADH PF00465.19 KKK11996.1 - 6.3e-35 120.7 3.5 9.8e-35 120.0 3.5 1.3 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fungal_trans PF04082.18 KKK11996.1 - 2.4e-14 53.0 0.3 3.6e-14 52.4 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fe-ADH_2 PF13685.6 KKK11996.1 - 1.7e-09 37.8 0.4 8.7e-09 35.4 0.4 1.9 2 0 0 2 2 2 1 Iron-containing alcohol dehydrogenase Zn_clus PF00172.18 KKK11996.1 - 1.4e-06 28.4 9.2 2.4e-06 27.6 9.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2HC5 PF06221.13 KKK12022.1 - 5.8e-21 74.2 6.1 9.3e-21 73.6 6.1 1.3 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type Sgf11 PF08209.11 KKK12023.1 - 2.5e-10 39.7 1.5 2.7e-10 39.6 0.1 1.8 2 0 0 2 2 2 1 Sgf11 (transcriptional regulation protein) zf-C2HC_2 PF13913.6 KKK12023.1 - 0.02 14.8 0.7 0.038 13.9 0.7 1.5 1 0 0 1 1 1 0 zinc-finger of a C2HC-type MFS_1 PF07690.16 KKK12024.1 - 1.4e-46 159.1 54.0 5.2e-46 157.2 54.0 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KKK12024.1 - 4.4e-10 38.6 23.5 5.5e-10 38.3 23.5 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Pacifastin_I PF05375.13 KKK12024.1 - 0.23 11.2 0.1 0.43 10.3 0.1 1.4 1 0 0 1 1 1 0 Pacifastin inhibitor (LCMII) Mpv17_PMP22 PF04117.12 KKK12025.1 - 1.3e-08 34.9 0.2 3.1e-08 33.7 0.2 1.6 1 0 0 1 1 1 1 Mpv17 / PMP22 family DUF1690 PF07956.11 KKK12026.1 - 1.2e-39 135.9 5.4 2.7e-19 70.0 0.2 2.0 2 0 0 2 2 2 2 Protein of Unknown function (DUF1690) ARA70 PF12489.8 KKK12026.1 - 0.0019 18.4 0.1 0.0031 17.7 0.1 1.3 1 0 0 1 1 1 1 Nuclear coactivator cwf21 PF08312.12 KKK12026.1 - 0.017 15.3 4.9 3.2 8.0 4.3 2.4 2 0 0 2 2 2 0 cwf21 domain Rootletin PF15035.6 KKK12026.1 - 0.025 14.6 2.2 0.34 10.9 0.2 2.1 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion Apolipoprotein PF01442.18 KKK12026.1 - 0.028 14.3 8.9 0.53 10.1 3.2 2.2 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain Herpes_UL25 PF01499.16 KKK12026.1 - 0.051 12.1 0.2 0.058 11.9 0.2 1.1 1 0 0 1 1 1 0 Herpesvirus UL25 family MRP-S26 PF14943.6 KKK12026.1 - 0.24 11.3 7.1 0.054 13.4 2.8 1.9 2 0 0 2 2 2 0 Mitochondrial ribosome subunit S26 Med9 PF07544.13 KKK12026.1 - 0.27 11.3 3.2 0.35 11.0 0.0 2.4 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 CdvA PF18822.1 KKK12026.1 - 0.81 9.5 7.0 0.68 9.8 0.8 2.4 3 0 0 3 3 3 0 CdvA-like coiled-coil domain FliT PF05400.13 KKK12026.1 - 4.8 8.1 10.0 0.18 12.6 2.8 2.2 3 0 0 3 3 3 0 Flagellar protein FliT Acetyltransf_1 PF00583.25 KKK12027.1 - 0.0046 17.2 0.0 0.032 14.5 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Importin_rep_4 PF18808.1 KKK12027.1 - 0.062 13.6 0.2 0.12 12.6 0.2 1.4 1 0 0 1 1 1 0 Importin repeat NAD_binding_6 PF08030.12 KKK12028.1 - 1.3e-19 70.9 0.0 1.5e-18 67.4 0.0 2.2 1 1 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 KKK12028.1 - 1e-18 67.7 12.4 2.7e-18 66.3 12.4 1.8 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KKK12028.1 - 4.6e-13 49.2 0.0 9e-13 48.3 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 KKK12028.1 - 0.0048 17.5 0.0 0.43 11.2 0.0 2.4 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain AKAP2_C PF15304.6 KKK12028.1 - 0.49 9.6 5.3 0.71 9.1 5.3 1.2 1 0 0 1 1 1 0 A-kinase anchor protein 2 C-terminus Hexokinase_2 PF03727.16 KKK12029.1 - 1.2e-80 270.4 0.0 1.6e-80 270.0 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 KKK12029.1 - 1.3e-72 243.9 0.0 1.7e-72 243.5 0.0 1.2 1 0 0 1 1 1 1 Hexokinase POP1 PF06978.11 KKK12030.1 - 2e-74 250.0 13.9 2e-74 250.0 13.9 1.9 3 0 0 3 3 3 1 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.12 KKK12030.1 - 1.2e-32 112.0 0.9 1.2e-32 112.0 0.9 2.3 2 0 0 2 2 2 1 POPLD (NUC188) domain DUF1263 PF06882.12 KKK12030.1 - 0.072 13.1 0.0 4.3 7.5 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1263) Adeno_terminal PF02459.15 KKK12030.1 - 5.1 5.4 5.6 8.3 4.7 5.6 1.2 1 0 0 1 1 1 0 Adenoviral DNA terminal protein Redoxin PF08534.10 KKK12031.1 - 9e-36 122.8 0.0 1e-35 122.6 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 KKK12031.1 - 2.9e-13 49.8 0.0 3.8e-13 49.4 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family DUF1348 PF07080.11 KKK12032.1 - 7.9e-56 187.5 2.5 9.4e-56 187.3 2.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1348) SnoaL_2 PF12680.7 KKK12032.1 - 3.6e-06 27.6 0.1 7.8e-06 26.5 0.1 1.6 1 1 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 KKK12032.1 - 2.6e-05 24.6 0.0 3.6e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) Pkinase PF00069.25 KKK12033.1 - 6.5e-66 222.4 0.0 2.5e-65 220.5 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Fungal_KA1 PF16797.5 KKK12033.1 - 3.3e-37 126.8 0.1 5.9e-37 126.0 0.1 1.4 1 0 0 1 1 1 1 Fungal kinase associated-1 domain Pkinase_Tyr PF07714.17 KKK12033.1 - 8.9e-36 123.5 0.0 3.6e-34 118.2 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KKK12033.1 - 0.00019 21.4 0.2 0.0097 15.9 0.1 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KKK12033.1 - 0.00021 20.4 0.0 0.0005 19.1 0.0 1.5 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KKK12033.1 - 0.00035 20.0 0.0 0.00061 19.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 KKK12033.1 - 0.023 14.3 0.0 0.059 13.0 0.0 1.6 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kinase-like PF14531.6 KKK12033.1 - 0.066 12.5 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Zn_clus PF00172.18 KKK12034.1 - 6.8e-09 35.7 7.4 9.8e-09 35.2 7.4 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_S10 PF00450.22 KKK12036.1 - 2.1e-91 307.5 2.1 5.2e-91 306.1 2.1 1.6 1 1 0 1 1 1 1 Serine carboxypeptidase Sugar_tr PF00083.24 KKK12037.1 - 1.8e-40 139.1 19.1 2.4e-21 76.1 8.4 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KKK12037.1 - 7.3e-26 90.9 23.8 2e-18 66.5 14.0 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily Glucosamine_iso PF01182.20 KKK12038.1 - 1.2e-20 74.3 0.0 2e-20 73.7 0.0 1.3 1 1 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Sugar-bind PF04198.13 KKK12038.1 - 0.021 14.0 0.1 0.032 13.4 0.1 1.3 1 0 0 1 1 1 0 Putative sugar-binding domain Zn_clus PF00172.18 KKK12039.1 - 6.1e-06 26.3 8.8 1e-05 25.5 8.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Hexokinase_2 PF03727.16 KKK12040.1 - 5.9e-64 215.8 0.0 3.5e-47 160.8 0.0 2.2 2 0 0 2 2 2 2 Hexokinase Hexokinase_1 PF00349.21 KKK12040.1 - 1.3e-61 208.0 0.0 1.9e-61 207.4 0.0 1.3 1 0 0 1 1 1 1 Hexokinase Bac_rhamnosid6H PF17389.2 KKK12042.1 - 7.9e-126 419.9 0.0 1.1e-125 419.4 0.0 1.2 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid_N PF08531.10 KKK12042.1 - 1.1e-55 188.1 0.0 2e-55 187.3 0.0 1.5 1 0 0 1 1 1 1 Alpha-L-rhamnosidase N-terminal domain Bac_rhamnosid_C PF17390.2 KKK12042.1 - 1.9e-24 85.2 0.1 4.1e-24 84.2 0.1 1.6 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase C-terminal domain Bac_rhamnosid PF05592.11 KKK12042.1 - 1.4e-23 82.8 0.0 3.2e-23 81.6 0.0 1.7 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase concanavalin-like domain NAGLU PF05089.12 KKK12043.1 - 3.8e-137 456.7 8.0 4.9e-137 456.3 8.0 1.1 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain NAGLU_C PF12972.7 KKK12043.1 - 4.1e-75 252.8 2.8 6.4e-75 252.1 2.8 1.3 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain NAGLU_N PF12971.7 KKK12043.1 - 3.3e-16 58.8 0.0 7.7e-16 57.7 0.0 1.7 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain AA_permease_2 PF13520.6 KKK12045.1 - 2.1e-56 191.6 56.1 2.6e-56 191.3 56.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KKK12045.1 - 1.7e-21 76.4 45.8 2.3e-21 76.0 45.8 1.0 1 0 0 1 1 1 1 Amino acid permease Abhydrolase_3 PF07859.13 KKK12046.1 - 2.3e-09 37.4 0.0 3.2e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KKK12046.1 - 1.4e-08 34.1 0.2 6.4e-08 31.9 0.2 1.8 1 1 0 1 1 1 1 Carboxylesterase family Chlorophyllase2 PF12740.7 KKK12046.1 - 7.3e-06 25.1 0.0 1.1e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Say1_Mug180 PF10340.9 KKK12046.1 - 3.6e-05 22.8 0.0 5.5e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase Abhydrolase_6 PF12697.7 KKK12046.1 - 0.00027 21.6 0.1 0.00045 20.9 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase PF07224.11 KKK12046.1 - 0.0003 19.9 0.0 0.00042 19.4 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase Glyco_hydro_30 PF02055.16 KKK12047.1 - 1.1e-33 116.7 2.2 1.7e-33 116.0 2.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Glyco_hydro_30C PF17189.4 KKK12047.1 - 5e-09 36.2 0.2 1.2e-08 35.1 0.2 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 beta sandwich domain Glyco_hydro_59 PF02057.15 KKK12047.1 - 0.0001 21.7 0.9 0.00031 20.1 0.9 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 59 PvlArgDC PF01862.16 KKK12047.1 - 0.094 12.5 0.1 7.3 6.4 0.0 2.4 2 0 0 2 2 2 0 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) Peptidase_M75 PF09375.10 KKK12047.1 - 0.3 10.5 1.7 0.56 9.6 0.6 1.9 3 0 0 3 3 3 0 Imelysin Mab-21 PF03281.14 KKK12048.1 - 0.062 12.6 0.1 0.094 12.0 0.1 1.2 1 0 0 1 1 1 0 Mab-21 protein Fungal_trans PF04082.18 KKK12049.1 - 3.9e-09 35.9 0.0 2.9e-08 33.1 0.0 2.3 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK12049.1 - 0.0017 18.5 14.3 0.0017 18.5 14.3 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DIOX_N PF14226.6 KKK12050.1 - 3.4e-18 66.5 0.0 6.3e-18 65.6 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KKK12050.1 - 2.4e-16 60.0 0.0 3.9e-16 59.4 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MFS_1 PF07690.16 KKK12051.1 - 5.5e-28 97.9 39.6 5.7e-28 97.9 36.6 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 KKK12051.1 - 3e-08 33.3 6.8 3e-08 33.3 6.8 2.1 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB FMN_dh PF01070.18 KKK12052.1 - 8.5e-105 350.6 0.1 1.4e-104 349.9 0.1 1.3 1 1 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 KKK12052.1 - 2.1e-22 79.0 0.0 5e-22 77.8 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain IMPDH PF00478.25 KKK12052.1 - 1.3e-05 24.4 0.9 2.6e-05 23.4 0.6 1.6 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 KKK12052.1 - 2.9e-05 23.4 0.1 4.6e-05 22.7 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.15 KKK12052.1 - 0.0017 17.8 0.2 0.0032 16.9 0.2 1.4 1 0 0 1 1 1 1 Nitronate monooxygenase DHO_dh PF01180.21 KKK12052.1 - 0.069 12.3 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase His_biosynth PF00977.21 KKK12052.1 - 0.096 12.1 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Histidine biosynthesis protein GMC_oxred_N PF00732.19 KKK12053.1 - 3e-55 187.7 0.0 3.9e-55 187.3 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KKK12053.1 - 2.6e-34 118.8 0.0 4e-34 118.2 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KKK12053.1 - 1.7e-05 24.1 1.1 0.046 12.8 0.8 2.2 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.17 KKK12053.1 - 9.6e-05 21.7 0.3 0.0004 19.7 0.1 1.9 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.6 KKK12053.1 - 0.0026 17.9 0.2 0.028 14.6 0.3 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KKK12053.1 - 0.0026 16.8 0.2 0.0063 15.6 0.1 1.6 2 0 0 2 2 2 1 Lycopene cyclase protein DAO PF01266.24 KKK12053.1 - 0.0031 17.2 0.5 0.0069 16.0 0.5 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KKK12053.1 - 0.015 14.6 0.0 0.034 13.4 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KKK12053.1 - 0.18 11.0 0.6 22 4.2 0.5 2.4 2 1 1 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Catalase PF00199.19 KKK12054.1 - 2.9e-173 576.4 0.0 3.4e-173 576.1 0.0 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 KKK12054.1 - 9.4e-14 51.4 0.0 2.1e-13 50.3 0.0 1.6 1 0 0 1 1 1 1 Catalase-related immune-responsive Peptidase_S10 PF00450.22 KKK12055.1 - 1.1e-77 262.2 0.0 1.5e-77 261.8 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Phosphoesterase PF04185.14 KKK12056.1 - 1.3e-74 251.5 4.0 1.8e-74 251.1 4.0 1.1 1 0 0 1 1 1 1 Phosphoesterase family Cu-oxidase_3 PF07732.15 KKK12057.1 - 3.2e-40 136.9 0.8 1.1e-38 132.0 0.1 2.9 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 KKK12057.1 - 2.7e-32 111.4 3.6 1.9e-30 105.4 0.1 3.2 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.22 KKK12057.1 - 5e-14 52.7 0.0 3.2e-13 50.1 0.0 2.2 2 0 0 2 2 2 1 Multicopper oxidase PhyH PF05721.13 KKK12058.1 - 2.6e-09 37.6 0.0 4.6e-09 36.8 0.0 1.4 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.12 KKK12058.1 - 1.5e-08 33.9 0.1 0.035 12.9 0.1 3.1 3 0 0 3 3 3 3 Protein of unknown function (DUF1479) Rad21_Rec8_N PF04825.13 KKK12150.1 - 4.6e-31 107.2 0.0 9.2e-31 106.3 0.0 1.5 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 KKK12150.1 - 0.021 14.1 0.3 0.051 12.9 0.0 1.8 2 0 0 2 2 2 0 Conserved region of Rad21 / Rec8 like protein FAD_binding_4 PF01565.23 KKK12152.1 - 5.8e-06 26.1 0.7 2.4e-05 24.1 0.4 2.1 2 0 0 2 2 2 1 FAD binding domain GFA PF04828.14 KKK12152.1 - 0.27 11.6 2.7 0.8 10.1 0.2 2.4 2 0 0 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme ADH_N PF08240.12 KKK12174.1 - 3.2e-23 81.7 0.3 5.9e-23 80.8 0.3 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KKK12174.1 - 1.3e-17 64.0 0.0 2.3e-17 63.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KKK12174.1 - 0.0037 18.3 0.0 0.011 16.8 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Glyco_hydro_76 PF03663.14 KKK12175.1 - 8.2e-140 466.5 21.5 9.7e-140 466.2 21.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 KKK12175.1 - 0.059 12.4 12.5 0.25 10.4 2.1 2.9 1 1 1 3 3 3 0 Glycosyl Hydrolase Family 88 LOR PF04525.12 KKK12176.1 - 3.2e-07 30.1 0.0 1.6e-06 27.8 0.0 2.0 1 1 0 1 1 1 1 LURP-one-related zf-PARP PF00645.18 KKK12178.1 - 0.015 16.2 0.0 0.033 15.0 0.0 1.5 1 0 0 1 1 1 0 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region Oxidored_FMN PF00724.20 KKK12179.1 - 1.1e-94 317.5 0.0 1.2e-94 317.4 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family PHA_synth_III_E PF09712.10 KKK12179.1 - 0.13 11.3 0.2 0.26 10.4 0.0 1.5 2 0 0 2 2 2 0 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) APH PF01636.23 KKK12180.1 - 0.0014 18.6 0.0 0.0036 17.2 0.0 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family TFIIIC_sub6 PF10419.9 KKK12190.1 - 3.8e-24 84.4 0.0 6.4e-24 83.7 0.0 1.4 1 0 0 1 1 1 1 TFIIIC subunit triple barrel domain Vps62 PF06101.11 KKK12191.1 - 2.4e-11 42.6 0.6 2.4e-11 42.6 0.6 1.7 2 0 0 2 2 2 1 Vacuolar protein sorting-associated protein 62 JmjC PF02373.22 KKK12192.1 - 4.8e-09 36.6 0.0 5.1e-08 33.3 0.0 2.4 1 1 0 1 1 1 1 JmjC domain, hydroxylase JHD PF17811.1 KKK12192.1 - 5.1e-09 36.6 0.3 1e-08 35.6 0.3 1.5 1 0 0 1 1 1 1 Jumonji helical domain Cupin_8 PF13621.6 KKK12192.1 - 2.8e-08 33.8 0.0 7.2e-08 32.5 0.0 1.7 1 0 0 1 1 1 1 Cupin-like domain PHD PF00628.29 KKK12192.1 - 4.3e-08 32.9 4.4 4.3e-08 32.9 4.4 2.7 3 0 0 3 3 3 1 PHD-finger PHD_2 PF13831.6 KKK12192.1 - 0.0054 16.3 4.4 0.0069 15.9 2.4 2.4 2 0 0 2 2 2 1 PHD-finger Dickkopf_N PF04706.12 KKK12192.1 - 0.62 10.6 9.8 6.8 7.3 0.8 3.0 2 0 0 2 2 2 0 Dickkopf N-terminal cysteine-rich region Zn_clus PF00172.18 KKK12192.1 - 3.1 8.0 28.3 0.16 12.1 5.2 3.2 3 0 0 3 3 3 0 Fungal Zn(2)-Cys(6) binuclear cluster domain STIMATE PF12400.8 KKK12193.1 - 3e-40 137.6 5.4 4.6e-40 137.1 4.4 1.8 2 0 0 2 2 2 1 STIMATE family RRM_1 PF00076.22 KKK12193.1 - 1.3e-18 66.5 0.4 2.1e-18 65.9 0.4 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KKK12193.1 - 4.9e-05 22.9 0.0 9.3e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KKK12193.1 - 0.016 15.0 0.0 0.028 14.3 0.0 1.3 1 0 0 1 1 1 0 Occluded RNA-recognition motif DUF4271 PF14093.6 KKK12193.1 - 0.21 11.5 5.5 0.52 10.2 5.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4271) PRIMA1 PF16101.5 KKK12193.1 - 1.4 8.9 3.7 1.4 9.0 1.3 2.1 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 Flavokinase PF01687.17 KKK12194.1 - 4.2e-31 107.5 0.0 9.5e-31 106.4 0.0 1.5 1 1 0 1 1 1 1 Riboflavin kinase Skp1 PF01466.19 KKK12194.1 - 0.046 13.8 0.3 0.081 13.1 0.3 1.4 1 0 0 1 1 1 0 Skp1 family, dimerisation domain Zn_clus PF00172.18 KKK12195.1 - 0.0081 16.3 9.2 0.017 15.2 9.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS PF00989.25 KKK12195.1 - 0.073 13.1 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 PAS fold MFS_1 PF07690.16 KKK12196.1 - 7.7e-43 146.8 31.6 9.3e-43 146.5 31.6 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KKK12196.1 - 1.6e-07 30.2 3.0 3.1e-07 29.2 3.0 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.13 KKK12196.1 - 0.0028 16.1 0.6 0.0043 15.5 0.6 1.2 1 0 0 1 1 1 1 Transmembrane secretion effector Rad21_Rec8_N PF04825.13 KKK12197.1 - 2.1e-37 127.7 0.1 3.8e-37 126.8 0.1 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 KKK12197.1 - 1.9e-07 30.3 0.2 4.1e-07 29.2 0.2 1.6 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein SMC_ScpA PF02616.14 KKK12197.1 - 0.024 14.6 0.2 0.072 13.0 0.1 1.8 2 0 0 2 2 2 0 Segregation and condensation protein ScpA E1-E2_ATPase PF00122.20 KKK12198.1 - 5e-45 153.2 0.4 5e-45 153.2 0.4 2.3 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 KKK12198.1 - 2.8e-43 147.7 3.4 4e-43 147.2 0.1 2.3 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Cation_ATPase_N PF00690.26 KKK12198.1 - 1.6e-19 69.3 0.1 3.3e-19 68.4 0.1 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase PF00702.26 KKK12198.1 - 2.6e-19 70.4 4.3 6e-18 65.9 4.3 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KKK12198.1 - 6.1e-13 48.7 0.0 1.2e-12 47.7 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KKK12198.1 - 3e-06 27.2 1.2 8.2e-05 22.5 0.9 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF2628 PF10947.8 KKK12198.1 - 2.8 8.3 4.1 1.4 9.3 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2628) Ammonium_transp PF00909.21 KKK12199.1 - 4.9e-118 394.3 31.5 5.6e-118 394.1 31.5 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family COG4 PF08318.12 KKK12200.1 - 7.6e-127 423.0 0.0 1.3e-126 422.2 0.0 1.4 1 0 0 1 1 1 1 COG4 transport protein FA_desaturase PF00487.24 KKK12200.1 - 0.003 17.4 4.1 0.005 16.7 4.1 1.2 1 0 0 1 1 1 1 Fatty acid desaturase NHase_alpha PF02979.16 KKK12200.1 - 0.17 11.2 0.0 0.4 10.0 0.0 1.6 1 0 0 1 1 1 0 Nitrile hydratase, alpha chain SIR2 PF02146.17 KKK12201.1 - 2.8e-55 187.0 0.0 3.8e-55 186.5 0.0 1.2 1 0 0 1 1 1 1 Sir2 family Hexokinase_2 PF03727.16 KKK12202.1 - 1.1e-79 267.3 0.0 1.4e-79 266.9 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 KKK12202.1 - 8.5e-72 241.2 0.0 1.2e-71 240.8 0.0 1.2 1 0 0 1 1 1 1 Hexokinase PhnJ PF06007.11 KKK12202.1 - 0.064 12.3 0.0 0.1 11.6 0.0 1.3 1 0 0 1 1 1 0 Phosphonate metabolism protein PhnJ WD40 PF00400.32 KKK12203.1 - 8.3e-07 29.6 0.5 0.0085 16.9 0.0 4.7 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKK12203.1 - 0.024 14.9 0.1 10 6.5 0.0 3.8 3 2 2 5 5 5 0 Anaphase-promoting complex subunit 4 WD40 domain NAP PF00956.18 KKK12212.1 - 5.1e-29 101.3 16.7 1.3e-27 96.7 11.8 2.5 2 1 1 3 3 3 2 Nucleosome assembly protein (NAP) Med8 PF10232.9 KKK12212.1 - 0.083 12.5 0.1 0.083 12.5 0.1 2.6 3 1 1 4 4 4 0 Mediator of RNA polymerase II transcription complex subunit 8 Methyltransf_32 PF13679.6 KKK12213.1 - 1.7e-23 83.3 0.2 5.6e-23 81.7 0.2 1.8 1 1 0 1 1 1 1 Methyltransferase domain Fungal_trans PF04082.18 KKK12214.1 - 2.4e-09 36.6 0.2 2.5e-08 33.3 0.0 2.5 3 1 0 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK12214.1 - 4.9e-09 36.2 13.3 9e-09 35.3 13.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain COX5A PF02284.16 KKK12215.1 - 3e-38 130.0 0.2 3.9e-38 129.6 0.2 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va LOH1CR12 PF10158.9 KKK12215.1 - 0.07 13.1 0.1 11 6.1 0.0 2.1 1 1 1 2 2 2 0 Tumour suppressor protein Glyco_transf_15 PF01793.16 KKK12216.1 - 1.5e-112 376.1 7.5 1.8e-112 375.8 7.5 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase NmrA PF05368.13 KKK12217.1 - 5e-66 222.6 0.0 1.4e-65 221.1 0.0 1.6 1 1 0 1 1 1 1 NmrA-like family Syntaxin-6_N PF09177.11 KKK12219.1 - 6.4e-26 90.8 0.2 2.5e-25 88.9 0.0 1.9 2 0 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.19 KKK12219.1 - 0.042 13.8 2.2 0.065 13.2 0.5 2.2 2 0 0 2 2 2 0 SNARE domain DUF4713 PF15831.5 KKK12219.1 - 0.044 14.2 1.8 0.17 12.4 1.8 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4713) DUF4795 PF16043.5 KKK12219.1 - 0.11 12.0 2.0 0.79 9.3 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) HMMR_N PF15905.5 KKK12219.1 - 0.52 9.7 3.1 0.43 10.0 0.1 1.9 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal DUF1515 PF07439.11 KKK12219.1 - 5.9 7.0 6.3 50 4.0 0.1 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1515) GATase_5 PF13507.6 KKK12220.1 - 9.2e-102 339.6 0.0 1.4e-101 339.0 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.22 KKK12220.1 - 1.5e-37 129.1 0.6 2.7e-24 86.1 0.3 2.7 3 0 0 3 3 3 2 AIR synthase related protein, C-terminal domain FGAR-AT_N PF18076.1 KKK12220.1 - 2.5e-33 114.5 0.0 4.6e-33 113.6 0.0 1.5 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase N-terminal FGAR-AT_linker PF18072.1 KKK12220.1 - 1.7e-13 50.9 0.0 4e-13 49.7 0.0 1.7 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase linker domain GCP_N_terminal PF17681.1 KKK12221.1 - 5.2e-42 144.5 6.4 3.3e-41 141.9 0.9 2.4 2 0 0 2 2 2 2 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 KKK12221.1 - 8.7e-29 100.9 0.8 1.9e-28 99.9 0.8 1.6 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP5-Mod21 PF14609.6 KKK12221.1 - 1.3e-07 30.4 0.1 4.6e-07 28.6 0.0 1.9 2 0 0 2 2 2 1 gamma-Tubulin ring complex non-core subunit mod21 Sigma70_ner PF04546.13 KKK12221.1 - 0.00051 20.0 1.5 0.0011 18.8 1.5 1.5 1 0 0 1 1 1 1 Sigma-70, non-essential region CENP-B_dimeris PF09026.10 KKK12221.1 - 0.0065 16.8 9.4 0.018 15.4 9.4 1.7 1 0 0 1 1 1 1 Centromere protein B dimerisation domain RXT2_N PF08595.11 KKK12221.1 - 0.35 10.9 5.6 0.76 9.8 5.6 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal Pox_Ag35 PF03286.14 KKK12221.1 - 0.41 10.4 3.9 0.94 9.2 3.9 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein NOA36 PF06524.12 KKK12221.1 - 0.49 9.7 8.3 0.73 9.1 8.3 1.2 1 0 0 1 1 1 0 NOA36 protein Cwf_Cwc_15 PF04889.12 KKK12221.1 - 1.8 8.2 11.1 0.078 12.7 5.3 1.6 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Fungal_trans PF04082.18 KKK12222.1 - 3.6e-06 26.2 0.0 8e-06 25.1 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK12222.1 - 3.7e-06 27.0 11.8 6.4e-06 26.2 11.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 KKK12223.1 - 4.9e-43 147.4 32.6 4.9e-43 147.4 32.6 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KKK12223.1 - 9.3e-11 41.2 2.7 9.3e-11 41.2 2.7 2.6 3 1 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 KKK12223.1 - 2.6e-09 36.1 2.1 4.9e-09 35.2 2.1 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) AA_permease_2 PF13520.6 KKK12224.1 - 5.3e-41 140.8 51.0 7.2e-41 140.4 51.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KKK12224.1 - 3.7e-15 55.5 46.3 5.6e-15 54.9 46.0 1.3 1 1 0 1 1 1 1 Amino acid permease PNTB PF02233.16 KKK12225.1 - 4.7e-176 586.2 23.1 4.7e-176 586.2 23.1 2.1 2 0 0 2 2 2 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.21 KKK12225.1 - 5.2e-69 231.8 1.9 6.6e-69 231.5 0.2 2.2 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.15 KKK12225.1 - 3.4e-45 153.7 0.0 8.1e-45 152.5 0.0 1.7 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain PNTB_4TM PF12769.7 KKK12225.1 - 7.4e-30 103.3 3.2 7.4e-30 103.3 3.2 5.1 4 2 2 6 6 6 1 4TM region of pyridine nucleotide transhydrogenase, mitoch 2-Hacid_dh_C PF02826.19 KKK12225.1 - 3e-05 23.4 0.2 0.12 11.7 0.1 2.7 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TPP_enzyme_M PF00205.22 KKK12225.1 - 0.013 15.2 0.4 0.12 12.1 0.4 2.5 1 1 0 1 1 1 0 Thiamine pyrophosphate enzyme, central domain ADH_zinc_N PF00107.26 KKK12225.1 - 0.016 15.2 0.2 0.1 12.6 0.1 2.5 1 1 1 2 2 2 0 Zinc-binding dehydrogenase Pyr_redox_2 PF07992.14 KKK12225.1 - 0.036 13.3 0.2 0.096 11.9 0.2 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FtsJ PF01728.19 KKK12225.1 - 0.049 13.8 0.0 77 3.3 0.0 3.5 2 1 1 3 3 3 0 FtsJ-like methyltransferase CP_ATPgrasp_1 PF04174.13 KKK12225.1 - 0.11 11.5 0.3 1.2 8.1 0.0 2.2 2 0 0 2 2 2 0 A circularly permuted ATPgrasp GIDA PF01134.22 KKK12225.1 - 0.13 11.3 0.9 0.25 10.4 0.9 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A ELO PF01151.18 KKK12227.1 - 2.2e-62 210.8 20.8 2.6e-62 210.6 20.8 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family adh_short_C2 PF13561.6 KKK12228.1 - 9.5e-64 215.2 0.0 1.2e-63 214.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KKK12228.1 - 2.1e-50 170.9 0.0 2.7e-50 170.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KKK12228.1 - 1.4e-06 28.3 0.0 6.1e-06 26.3 0.0 1.8 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KKK12228.1 - 5.4e-05 22.8 0.0 9.1e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family AdoHcyase_NAD PF00670.21 KKK12228.1 - 0.11 12.6 0.1 0.22 11.6 0.1 1.5 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Fungal_trans_2 PF11951.8 KKK12229.1 - 3.3e-36 124.9 0.1 4.2e-36 124.6 0.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK12229.1 - 8.1e-09 35.5 8.2 1.4e-08 34.7 8.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ATP-synt_DE_N PF02823.16 KKK12231.1 - 1.4e-15 57.0 0.1 2.2e-15 56.3 0.1 1.4 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain Cytochrom_B561 PF03188.16 KKK12232.1 - 2.3e-05 24.5 7.5 0.00026 21.1 8.8 1.9 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 DUF998 PF06197.13 KKK12232.1 - 0.006 16.2 11.7 0.14 11.8 7.8 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF998) DUF4079 PF13301.6 KKK12232.1 - 8.4 6.5 12.5 11 6.2 2.6 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF4079) DUF3759 PF12585.8 KKK12232.1 - 10 6.3 10.2 11 6.1 0.0 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF3759) Glyco_transf_90 PF05686.12 KKK12233.1 - 2.4e-12 46.5 0.7 3.9e-09 35.9 0.1 3.2 3 0 0 3 3 3 3 Glycosyl transferase family 90 Metal_resist PF13801.6 KKK12233.1 - 0.13 12.4 0.7 0.33 11.1 0.1 1.9 2 0 0 2 2 2 0 Heavy-metal resistance Ribosomal_L29e PF01779.17 KKK12234.1 - 2.3e-10 40.6 0.4 4.8e-10 39.6 0.4 1.5 1 0 0 1 1 1 1 Ribosomal L29e protein family PQ-loop PF04193.14 KKK12235.1 - 1.2e-38 130.7 8.5 6.9e-20 70.6 1.4 2.5 2 0 0 2 2 2 2 PQ loop repeat DUF2374 PF09574.10 KKK12235.1 - 0.7 9.8 4.8 2.5 8.0 1.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (Duf2374) zf-C2H2 PF00096.26 KKK12236.1 - 0.00019 21.7 7.5 0.0038 17.6 0.1 3.2 3 0 0 3 3 3 2 Zinc finger, C2H2 type FOXP-CC PF16159.5 KKK12236.1 - 0.0019 18.8 1.1 0.21 12.3 0.1 2.7 2 0 0 2 2 2 2 FOXP coiled-coil domain zf-C2H2_4 PF13894.6 KKK12236.1 - 0.024 15.4 15.3 0.077 13.9 0.1 4.6 5 0 0 5 5 5 0 C2H2-type zinc finger zf-C2H2 PF00096.26 KKK12237.1 - 2.2e-08 34.1 12.1 0.00038 20.8 3.2 3.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KKK12237.1 - 0.00017 21.8 4.8 0.00017 21.8 4.8 3.8 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KKK12237.1 - 0.0037 18.0 2.4 0.0037 18.0 2.4 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger FOXP-CC PF16159.5 KKK12237.1 - 0.043 14.4 9.7 0.58 10.8 0.5 3.2 3 1 1 4 4 4 0 FOXP coiled-coil domain zf-C2H2_6 PF13912.6 KKK12237.1 - 1.3 9.1 9.8 3.6 7.7 0.6 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger BCNT PF07572.12 KKK12238.1 - 1e-25 89.6 0.1 3.1e-25 88.0 0.1 1.8 1 0 0 1 1 1 1 Bucentaur or craniofacial development Glyco_hydro_28 PF00295.17 KKK12240.1 - 3.1e-122 407.7 18.5 3.6e-122 407.5 18.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Ribonuclease_T2 PF00445.18 KKK12241.1 - 7.7e-44 150.1 2.2 1.2e-43 149.5 2.2 1.1 1 0 0 1 1 1 1 Ribonuclease T2 family GT-D PF08759.11 KKK12241.1 - 0.015 15.0 0.5 0.022 14.5 0.5 1.3 1 0 0 1 1 1 0 Glycosyltransferase GT-D fold bZIP_1 PF00170.21 KKK12242.1 - 2e-05 24.6 1.2 4.1e-05 23.6 1.2 1.5 1 0 0 1 1 1 1 bZIP transcription factor Chorion_2 PF03964.15 KKK12242.1 - 0.0016 19.2 3.9 0.0016 19.2 3.9 1.9 2 0 0 2 2 2 1 Chorion family 2 IMUP PF15761.5 KKK12242.1 - 0.072 13.8 7.3 0.15 12.7 7.3 1.6 1 0 0 1 1 1 0 Immortalisation up-regulated protein Rav1p_C PF12234.8 KKK12242.1 - 0.085 11.2 0.2 0.11 10.9 0.2 1.1 1 0 0 1 1 1 0 RAVE protein 1 C terminal DUF4692 PF15763.5 KKK12242.1 - 0.59 10.6 3.5 1.5 9.2 3.5 1.7 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) FliD_N PF02465.18 KKK12242.1 - 0.6 10.8 8.2 8 7.2 0.2 2.4 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus MJ1316 PF04457.12 KKK12243.1 - 1.1e-16 61.4 0.3 2.5e-16 60.2 0.3 1.6 1 0 0 1 1 1 1 MJ1316 RNA cyclic group end recognition domain MIF PF01187.18 KKK12243.1 - 5.5e-07 29.9 0.4 8.7e-07 29.2 0.4 1.3 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) Macro PF01661.21 KKK12244.1 - 2.3e-10 40.5 0.0 1e-09 38.5 0.0 1.9 1 1 0 1 1 1 1 Macro domain 2C_adapt PF08793.10 KKK12244.1 - 0.11 12.7 0.0 0.22 11.7 0.0 1.4 1 0 0 1 1 1 0 2-cysteine adaptor domain NAD_Gly3P_dh_N PF01210.23 KKK12244.1 - 0.17 11.9 0.0 0.25 11.3 0.0 1.2 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DUF202 PF02656.15 KKK12245.1 - 0.0039 17.6 0.3 0.0039 17.6 0.3 3.2 2 1 1 3 3 3 1 Domain of unknown function (DUF202) Claudin_2 PF13903.6 KKK12245.1 - 0.019 14.7 4.3 3.3 7.4 2.8 2.9 2 1 1 3 3 3 0 PMP-22/EMP/MP20/Claudin tight junction DUF4395 PF14340.6 KKK12245.1 - 0.3 11.4 8.5 0.09 13.1 3.9 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4395) Phage_holin_3_6 PF07332.11 KKK12245.1 - 7.6 6.6 14.0 0.79 9.8 4.6 2.7 3 0 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III Amidohydro_1 PF01979.20 KKK12246.1 - 2.6e-06 27.0 0.0 4.9e-06 26.1 0.0 1.5 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_2 PF04909.14 KKK12246.1 - 1.9e-05 24.6 0.0 2.7e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase Mis12 PF05859.12 KKK12247.1 - 2.7e-47 160.2 0.0 4.5e-47 159.5 0.0 1.4 1 0 0 1 1 1 1 Mis12 protein DUF4865 PF16157.5 KKK12247.1 - 0.15 12.1 0.0 0.25 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4865) Dus PF01207.17 KKK12248.1 - 3.7e-55 187.2 0.0 5.9e-55 186.5 0.0 1.2 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) DHO_dh PF01180.21 KKK12248.1 - 0.0098 15.1 0.0 0.015 14.5 0.0 1.2 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase CENP-X PF09415.10 KKK12249.1 - 3.8e-26 91.2 0.0 7.6e-26 90.2 0.0 1.5 1 0 0 1 1 1 1 CENP-S associating Centromere protein X FAM60A PF15396.6 KKK12249.1 - 0.053 13.5 3.7 0.059 13.4 3.7 1.2 1 0 0 1 1 1 0 Protein Family FAM60A Apt1 PF10351.9 KKK12249.1 - 0.11 11.3 6.2 0.11 11.3 6.2 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Dicty_REP PF05086.12 KKK12249.1 - 1.5 6.7 8.3 1.6 6.6 8.3 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Ndc1_Nup PF09531.10 KKK12249.1 - 1.9 7.1 13.1 2.2 6.8 13.1 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Fungal_trans PF04082.18 KKK12250.1 - 1e-13 51.0 0.5 3.3e-13 49.3 0.5 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.6 KKK12250.1 - 6.7e-07 29.5 8.5 6.7e-07 29.5 8.5 3.5 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.26 KKK12250.1 - 1.5e-06 28.3 15.2 0.0072 16.7 2.0 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-met PF12874.7 KKK12250.1 - 9.8e-05 22.6 8.3 0.052 13.9 0.9 2.6 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 KKK12250.1 - 0.00014 22.4 16.7 0.013 16.3 1.8 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KKK12250.1 - 0.0026 18.0 10.3 0.12 12.6 3.6 2.4 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KKK12250.1 - 0.0028 17.6 8.4 0.015 15.3 1.5 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-RING_2 PF13639.6 KKK12250.1 - 0.028 14.7 2.9 3.6 8.0 0.0 3.9 4 0 0 4 4 4 0 Ring finger domain PHD_4 PF16866.5 KKK12250.1 - 0.22 11.6 1.4 0.48 10.5 1.4 1.5 1 0 0 1 1 1 0 PHD-finger Collagen PF01391.18 KKK12251.1 - 7.9 6.3 15.2 5.8 6.7 2.1 2.4 2 0 0 2 2 2 0 Collagen triple helix repeat (20 copies) Vps52 PF04129.12 KKK12252.1 - 4e-111 372.2 0.0 5.4e-111 371.8 0.0 1.1 1 0 0 1 1 1 1 Vps52 / Sac2 family DAO PF01266.24 KKK12252.1 - 9.6e-42 143.8 0.0 1.7e-41 143.0 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Sec8_exocyst PF04048.14 KKK12252.1 - 0.025 14.5 0.0 0.075 12.9 0.0 1.8 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain Exo70 PF03081.15 KKK12252.1 - 0.11 11.5 1.1 1.6 7.7 0.0 2.7 3 0 0 3 3 3 0 Exo70 exocyst complex subunit Sec3_C PF09763.9 KKK12252.1 - 0.21 9.9 1.3 0.37 9.1 0.1 1.7 1 1 0 2 2 2 0 Exocyst complex component Sec3 eIF-5a PF01287.20 KKK12253.1 - 7.6e-24 83.6 1.3 1.7e-23 82.5 1.3 1.6 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 KKK12253.1 - 0.053 13.6 0.3 0.14 12.2 0.0 1.9 2 0 0 2 2 2 0 Elongation factor P (EF-P) KOW-like domain Helo_like_N PF17111.5 KKK12255.1 - 0.036 13.4 0.0 0.074 12.4 0.0 1.5 1 1 0 1 1 1 0 Fungal N-terminal domain of STAND proteins DNA_repr_REX1B PF14966.6 KKK12255.1 - 0.16 12.6 0.0 0.35 11.6 0.0 1.6 2 0 0 2 2 2 0 DNA repair REX1-B Pyr_redox_2 PF07992.14 KKK12256.1 - 2.3e-45 155.1 0.1 3.1e-45 154.7 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KKK12256.1 - 6.7e-19 68.2 1.7 2.3e-14 53.7 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Rhodanese PF00581.20 KKK12256.1 - 9.4e-10 39.0 0.0 2.5e-08 34.4 0.0 2.8 3 0 0 3 3 3 1 Rhodanese-like domain FAD_binding_2 PF00890.24 KKK12256.1 - 3.3e-08 33.1 2.7 3.6e-05 23.0 0.0 2.6 2 0 0 2 2 2 2 FAD binding domain AlaDh_PNT_C PF01262.21 KKK12256.1 - 1.9e-07 30.6 1.7 0.0092 15.3 0.1 2.6 3 0 0 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_8 PF13450.6 KKK12256.1 - 2.7e-07 30.7 5.6 0.0022 18.2 0.7 3.1 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KKK12256.1 - 4.8e-07 29.3 4.6 0.0025 17.1 1.1 3.0 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KKK12256.1 - 2.1e-06 27.6 7.4 0.0003 20.5 0.0 3.1 2 1 0 3 3 3 2 FAD dependent oxidoreductase HI0933_like PF03486.14 KKK12256.1 - 1.8e-05 23.7 8.9 0.092 11.4 1.0 3.3 2 1 1 3 3 3 2 HI0933-like protein Pyr_redox_dim PF02852.22 KKK12256.1 - 3.4e-05 24.1 0.0 0.00013 22.2 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain TrkA_N PF02254.18 KKK12256.1 - 3.5e-05 24.0 0.8 0.0018 18.5 0.0 2.4 2 0 0 2 2 2 1 TrkA-N domain Lycopene_cycl PF05834.12 KKK12256.1 - 0.00013 21.2 7.7 0.22 10.5 0.3 3.3 2 1 1 3 3 3 3 Lycopene cyclase protein GIDA PF01134.22 KKK12256.1 - 0.00052 19.2 1.9 0.027 13.6 0.4 2.3 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_7 PF13241.6 KKK12256.1 - 0.0026 18.2 1.3 0.5 10.8 0.0 2.5 1 1 1 2 2 2 1 Putative NAD(P)-binding 3HCDH_N PF02737.18 KKK12256.1 - 0.0044 16.9 0.0 0.0099 15.8 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 KKK12256.1 - 0.0058 15.9 3.1 0.12 11.6 0.1 2.2 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.7 KKK12256.1 - 0.0061 16.0 10.0 0.0082 15.5 1.8 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.19 KKK12256.1 - 0.0094 15.3 0.6 0.022 14.1 0.0 1.8 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Thi4 PF01946.17 KKK12256.1 - 0.024 13.9 1.2 4.1 6.6 0.1 2.3 2 0 0 2 2 2 0 Thi4 family XdhC_C PF13478.6 KKK12256.1 - 0.039 14.5 0.0 0.57 10.7 0.0 2.3 2 0 0 2 2 2 0 XdhC Rossmann domain Amino_oxidase PF01593.24 KKK12256.1 - 0.31 10.3 1.3 0.87 8.8 0.1 2.0 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase F420_oxidored PF03807.17 KKK12256.1 - 0.4 11.3 2.1 16 6.2 0.0 2.5 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Trp_halogenase PF04820.14 KKK12256.1 - 0.75 8.6 5.4 0.98 8.2 0.7 2.1 2 0 0 2 2 2 0 Tryptophan halogenase tRNA-synt_2 PF00152.20 KKK12257.1 - 2.2e-65 220.8 0.0 3e-65 220.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) DUF2156 PF09924.9 KKK12257.1 - 7e-12 45.0 0.0 1e-11 44.4 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2156) tRNA-synt_2d PF01409.20 KKK12257.1 - 0.0021 17.6 0.3 0.11 11.9 0.0 2.8 3 0 0 3 3 3 1 tRNA synthetases class II core domain (F) tRNA_anti-codon PF01336.25 KKK12257.1 - 0.0037 17.2 0.0 0.0073 16.3 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain MCM_N PF14551.6 KKK12257.1 - 0.065 13.8 0.0 0.15 12.7 0.0 1.6 1 0 0 1 1 1 0 MCM N-terminal domain RRM_1 PF00076.22 KKK12258.1 - 5e-80 263.3 3.6 1.3e-20 73.0 0.1 5.3 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 KKK12258.1 - 1.2e-28 99.0 0.5 8.6e-28 96.3 0.7 2.3 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain RRM_5 PF13893.6 KKK12258.1 - 3.7e-12 46.0 0.8 0.0024 17.5 0.0 5.1 3 2 2 5 5 5 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KKK12258.1 - 1.9e-05 24.7 0.9 9.7 6.4 0.0 5.4 4 3 0 4 4 4 2 RNA recognition motif Nup35_RRM_2 PF14605.6 KKK12258.1 - 3e-05 23.9 0.6 0.77 9.8 0.0 4.2 4 0 0 4 4 4 1 Nup53/35/40-type RNA recognition motif YflT PF11181.8 KKK12258.1 - 0.00021 21.7 0.9 0.046 14.2 0.7 2.8 2 0 0 2 2 2 1 Heat induced stress protein YflT CbiG_mid PF11761.8 KKK12258.1 - 0.00098 19.2 0.0 4.8 7.4 0.0 3.5 3 0 0 3 3 3 1 Cobalamin biosynthesis central region RRM_3 PF08777.11 KKK12258.1 - 0.0091 16.0 8.8 0.47 10.5 1.8 4.4 4 2 1 5 5 5 1 RNA binding motif AAR2 PF05282.11 KKK12258.1 - 0.076 12.4 1.1 0.13 11.6 1.1 1.5 1 0 0 1 1 1 0 AAR2 protein CSD PF00313.22 KKK12258.1 - 0.083 12.8 1.2 65 3.5 0.1 3.6 3 0 0 3 3 3 0 'Cold-shock' DNA-binding domain Fungal_trans PF04082.18 KKK12259.1 - 1.1e-16 60.7 4.8 1.7e-11 43.7 0.2 2.4 1 1 1 2 2 2 2 Fungal specific transcription factor domain Kdo PF06293.14 KKK12260.1 - 4.9e-05 22.8 0.1 9.2e-05 21.9 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KKK12260.1 - 0.00057 19.9 6.8 0.002 18.1 0.5 2.9 2 1 1 3 3 3 2 Phosphotransferase enzyme family Choline_kinase PF01633.20 KKK12260.1 - 0.015 14.9 0.0 0.037 13.6 0.0 1.6 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF2828 PF11443.8 KKK12260.1 - 0.049 11.7 0.0 0.076 11.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Pkinase PF00069.25 KKK12260.1 - 0.19 11.1 0.3 0.52 9.6 0.0 1.8 2 0 0 2 2 2 0 Protein kinase domain DUF3523 PF12037.8 KKK12260.1 - 0.83 9.0 11.6 1.5 8.1 11.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3523) HECT PF00632.25 KKK12261.1 - 9.2e-84 281.5 0.0 1.4e-83 280.9 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) IQ PF00612.27 KKK12261.1 - 0.049 13.4 1.6 0.16 11.8 1.6 1.9 1 0 0 1 1 1 0 IQ calmodulin-binding motif Trypan_PARP PF05887.11 KKK12262.1 - 0.025 14.6 5.1 0.033 14.2 5.1 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) TonB_N PF16031.5 KKK12262.1 - 0.034 14.7 5.7 0.053 14.0 5.7 1.3 1 0 0 1 1 1 0 TonB polyproline region SPESP1 PF15754.5 KKK12262.1 - 0.45 9.6 3.1 0.63 9.2 3.1 1.2 1 0 0 1 1 1 0 Sperm equatorial segment protein 1 CoA_trans PF01144.23 KKK12263.1 - 1.4e-96 322.1 1.6 2.5e-58 197.1 0.4 2.0 2 0 0 2 2 2 2 Coenzyme A transferase DUF531 PF04407.12 KKK12263.1 - 0.035 14.2 0.0 0.24 11.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF531) AhpC-TSA PF00578.21 KKK12265.1 - 2.2e-29 101.9 0.0 3e-29 101.5 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family 1-cysPrx_C PF10417.9 KKK12265.1 - 8e-14 51.2 0.1 1.3e-13 50.5 0.1 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Redoxin PF08534.10 KKK12265.1 - 9.5e-13 48.1 0.0 1.2e-12 47.8 0.0 1.1 1 0 0 1 1 1 1 Redoxin Condensation PF00668.20 KKK12266.1 - 1.4e-61 208.6 0.1 3.6e-61 207.2 0.1 1.5 1 1 0 1 1 1 1 Condensation domain AMP-binding PF00501.28 KKK12266.1 - 2.4e-58 197.7 0.2 3.9e-58 197.0 0.2 1.4 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 KKK12266.1 - 1e-26 93.7 0.0 4.2e-23 81.8 0.0 3.2 1 1 0 1 1 1 1 Male sterility protein PP-binding PF00550.25 KKK12266.1 - 4.1e-25 87.9 2.0 3.7e-14 52.8 0.1 2.9 3 0 0 3 3 3 2 Phosphopantetheine attachment site Epimerase PF01370.21 KKK12266.1 - 9e-05 22.0 0.0 0.00078 19.0 0.0 2.2 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KKK12266.1 - 0.0084 15.1 0.0 0.016 14.2 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Hydantoinase_B PF02538.14 KKK12268.1 - 3.5e-219 728.5 0.5 4.3e-219 728.2 0.5 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 KKK12268.1 - 8.7e-101 337.0 0.1 1.4e-99 333.1 0.0 2.1 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 KKK12268.1 - 3.1e-56 189.9 0.0 2.1e-53 180.7 0.0 2.5 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region Methyltransf_11 PF08241.12 KKK12275.1 - 7.4e-09 36.1 0.0 1.5e-08 35.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KKK12275.1 - 4.8e-08 33.0 0.0 7.7e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KKK12275.1 - 9.4e-07 29.5 0.0 2e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKK12275.1 - 2.2e-05 25.1 0.0 6.6e-05 23.5 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KKK12275.1 - 0.0049 16.7 0.0 0.023 14.5 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Dynactin_p62 PF05502.13 KKK12276.1 - 7e-189 628.5 0.2 1.3e-188 627.6 0.0 1.5 1 1 1 2 2 2 1 Dynactin p62 family Cwf_Cwc_15 PF04889.12 KKK12276.1 - 0.01 15.6 7.9 0.01 15.6 7.9 1.8 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Sporozoite_P67 PF05642.11 KKK12276.1 - 0.13 10.3 5.6 0.26 9.3 5.6 1.4 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Sigma70_ner PF04546.13 KKK12276.1 - 0.44 10.4 6.0 0.92 9.3 6.0 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region DNA_pol_phi PF04931.13 KKK12276.1 - 1.7 6.6 16.9 2.6 6.1 16.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi DUF1115 PF06544.12 KKK12276.1 - 1.9 8.6 5.4 1.3 9.1 3.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1115) FAM176 PF14851.6 KKK12276.1 - 4.6 6.9 10.2 12 5.6 6.4 2.3 2 0 0 2 2 2 0 FAM176 family FdhE PF04216.12 KKK12276.1 - 5 6.9 6.8 10 5.9 6.8 1.5 1 1 0 1 1 1 0 Protein involved in formate dehydrogenase formation Nop14 PF04147.12 KKK12276.1 - 6.8 4.8 13.7 0.13 10.5 7.0 1.4 2 0 0 2 2 2 0 Nop14-like family Mu-like_Com PF10122.9 KKK12276.1 - 8.1 6.0 8.1 8.6 5.9 2.5 2.8 2 0 0 2 2 2 0 Mu-like prophage protein Com Ribosomal_S7e PF01251.18 KKK12277.1 - 3.8e-83 277.8 0.2 4.8e-83 277.5 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S7e P16-Arc PF04699.14 KKK12278.1 - 1.6e-46 158.5 0.0 1.9e-46 158.2 0.0 1.1 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) Cupin_2 PF07883.11 KKK12284.1 - 9.9e-07 28.4 0.0 1.7e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.12 KKK12284.1 - 0.028 14.1 0.0 0.072 12.8 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF861) Alpha-L-AF_C PF06964.12 KKK12286.1 - 0.18 11.9 0.0 0.32 11.1 0.0 1.4 1 0 0 1 1 1 0 Alpha-L-arabinofuranosidase C-terminal domain Rubella_E2 PF05749.11 KKK12295.1 - 0.61 9.5 6.0 1.1 8.6 6.0 1.4 1 0 0 1 1 1 0 Rubella membrane glycoprotein E2 betaPIX_CC PF16523.5 KKK12295.1 - 4 7.3 13.5 16 5.4 12.1 2.1 1 1 1 2 2 2 0 betaPIX coiled coil His_Phos_1 PF00300.22 KKK12296.1 - 2.7e-15 56.6 0.0 1.3e-14 54.3 0.0 1.9 1 1 1 2 2 2 1 Histidine phosphatase superfamily (branch 1) DAO PF01266.24 KKK12296.1 - 0.061 12.9 0.3 0.09 12.3 0.3 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase DUF1248 PF06852.12 KKK12296.1 - 0.12 11.8 0.1 0.24 10.8 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1248) Ank_2 PF12796.7 KKK12297.1 - 7e-87 286.1 5.3 8.6e-22 77.5 0.2 8.9 4 2 3 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KKK12297.1 - 7e-74 243.3 7.5 9.5e-12 45.2 0.0 11.8 5 2 6 12 12 12 10 Ankyrin repeats (many copies) Ank_5 PF13857.6 KKK12297.1 - 2e-65 216.0 15.1 3.2e-08 33.7 0.1 13.6 4 2 9 14 14 14 13 Ankyrin repeats (many copies) Ank_3 PF13606.6 KKK12297.1 - 3.5e-60 192.8 2.8 5.7e-06 26.3 0.0 16.4 17 0 0 17 17 17 10 Ankyrin repeat Ank PF00023.30 KKK12297.1 - 5.3e-52 172.1 14.8 5.8e-08 32.8 0.0 14.5 16 0 0 16 16 16 7 Ankyrin repeat CorA PF01544.18 KKK12297.1 - 0.0039 16.6 2.2 0.0039 16.6 2.2 1.9 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein NPR1_interact PF15699.5 KKK12297.1 - 0.083 13.5 0.5 0.23 12.1 0.5 1.7 1 0 0 1 1 1 0 NPR1 interacting Glyco_hydro_43 PF04616.14 KKK12298.1 - 7.8e-45 153.4 9.5 1.2e-37 129.8 1.2 2.1 2 0 0 2 2 2 2 Glycosyl hydrolases family 43 Pkinase PF00069.25 KKK12299.1 - 1e-73 247.9 0.0 1.2e-73 247.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK12299.1 - 8.1e-38 130.2 0.0 9.8e-38 129.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KKK12299.1 - 0.00015 20.8 0.0 0.041 12.8 0.0 2.1 2 0 0 2 2 2 2 Haspin like kinase domain Kinase-like PF14531.6 KKK12299.1 - 0.0003 20.2 0.0 0.00058 19.3 0.0 1.6 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 KKK12299.1 - 0.006 16.5 0.2 0.0093 15.9 0.2 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KKK12299.1 - 0.006 16.0 0.2 0.011 15.1 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 KKK12299.1 - 0.089 11.8 0.0 0.19 10.7 0.0 1.5 1 0 0 1 1 1 0 Seadornavirus VP7 Fe-ADH PF00465.19 KKK12300.1 - 9.6e-100 333.9 0.1 1.2e-99 333.6 0.1 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 KKK12300.1 - 4.5e-16 59.3 0.0 7.5e-12 45.5 0.0 2.3 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Peripla_BP_6 PF13458.6 KKK12300.1 - 0.0012 18.6 0.0 0.0022 17.7 0.0 1.4 1 0 0 1 1 1 1 Periplasmic binding protein Arylsulfotran_2 PF14269.6 KKK12301.1 - 3.7e-110 368.0 5.4 4.4e-110 367.7 5.4 1.1 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 KKK12301.1 - 8.2e-05 21.7 4.4 0.00048 19.1 4.3 1.9 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) SusE PF14292.6 KKK12301.1 - 0.16 12.2 0.4 0.54 10.5 0.0 2.0 2 0 0 2 2 2 0 SusE outer membrane protein Bys1 PF04681.12 KKK12302.1 - 3e-08 33.7 0.0 3.4e-08 33.6 0.0 1.1 1 0 0 1 1 1 1 Blastomyces yeast-phase-specific protein Imm65 PF15582.6 KKK12302.1 - 0.18 10.6 0.0 0.21 10.4 0.0 1.0 1 0 0 1 1 1 0 Immunity protein 65 BNR_2 PF13088.6 KKK12303.1 - 1.3e-05 24.6 0.0 0.0059 15.9 0.0 2.8 1 1 2 3 3 3 2 BNR repeat-like domain BNR PF02012.20 KKK12303.1 - 2.6e-05 23.6 2.3 0.033 14.1 0.1 3.4 2 0 0 2 2 2 2 BNR/Asp-box repeat Sortilin-Vps10 PF15902.5 KKK12303.1 - 0.0049 15.7 0.0 0.43 9.3 0.0 2.2 2 0 0 2 2 2 2 Sortilin, neurotensin receptor 3, BNR_6 PF15899.5 KKK12303.1 - 0.011 15.7 0.3 0.72 10.1 0.0 2.7 2 0 0 2 2 2 0 BNR-Asp box repeat zf-C2H2_2 PF12756.7 KKK12304.1 - 4e-39 133.0 10.9 8.6e-32 109.5 2.7 3.4 3 0 0 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 KKK12304.1 - 1.6e-07 31.4 6.1 1.6e-07 31.4 6.1 4.1 4 1 0 4 4 4 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KKK12304.1 - 1.3e-05 25.5 4.7 1.3e-05 25.5 4.7 3.1 3 0 0 3 3 3 1 Zinc-finger of C2H2 type DUF2024 PF09630.10 KKK12304.1 - 0.003 17.4 3.9 0.57 10.1 0.3 2.7 2 0 0 2 2 2 2 Domain of unknown function (DUF2024) zf-LYAR PF08790.11 KKK12304.1 - 0.0031 17.4 4.4 0.0067 16.3 0.7 2.8 2 0 0 2 2 2 1 LYAR-type C2HC zinc finger zf-C2H2 PF00096.26 KKK12304.1 - 0.023 15.2 18.9 0.063 13.8 0.4 4.4 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KKK12304.1 - 0.043 14.7 12.9 0.65 11.0 0.6 4.4 4 0 0 4 4 4 0 C2H2-type zinc finger Cytochrome_C554 PF13435.6 KKK12304.1 - 0.052 14.5 8.3 5.2 8.1 0.3 3.8 3 0 0 3 3 3 0 Cytochrome c554 and c-prime HECT PF00632.25 KKK12305.1 - 1.8e-71 241.2 0.0 9.6e-71 238.8 0.0 2.0 1 1 0 1 1 1 1 HECT-domain (ubiquitin-transferase) AZUL PF16558.5 KKK12305.1 - 1.6e-21 76.2 2.2 4.1e-21 75.0 2.2 1.8 1 0 0 1 1 1 1 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A FAD_binding_3 PF01494.19 KKK12306.1 - 6.4e-23 81.6 0.0 9e-23 81.1 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KKK12306.1 - 2.1e-08 33.8 1.3 0.00012 21.4 0.2 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KKK12306.1 - 1.6e-05 24.7 10.5 0.011 15.4 4.4 3.0 2 1 1 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KKK12306.1 - 0.00022 21.4 3.0 0.00029 21.0 1.6 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KKK12306.1 - 0.00026 20.2 4.1 0.00026 20.2 4.1 2.1 3 0 0 3 3 3 1 FAD binding domain HI0933_like PF03486.14 KKK12306.1 - 0.0013 17.5 3.3 0.012 14.3 1.3 2.1 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.22 KKK12306.1 - 0.0065 15.6 3.2 0.018 14.1 3.2 1.6 1 1 0 1 1 1 1 Glucose inhibited division protein A Lycopene_cycl PF05834.12 KKK12306.1 - 0.007 15.5 1.2 0.016 14.3 1.2 1.6 1 1 0 1 1 1 1 Lycopene cyclase protein Amino_oxidase PF01593.24 KKK12306.1 - 0.043 13.1 1.6 1.9 7.7 0.1 2.4 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Trp_halogenase PF04820.14 KKK12306.1 - 0.091 11.6 3.2 6.3 5.5 0.1 2.6 3 0 0 3 3 3 0 Tryptophan halogenase FAD_oxidored PF12831.7 KKK12306.1 - 0.1 12.0 4.4 0.15 11.3 2.9 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KKK12306.1 - 0.1 11.9 2.3 2.4 7.3 1.7 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KKK12306.1 - 0.13 11.5 1.9 0.43 9.8 0.3 2.0 2 0 0 2 2 2 0 Thi4 family AlaDh_PNT_C PF01262.21 KKK12306.1 - 0.16 11.2 3.2 0.31 10.3 3.2 1.6 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 KKK12306.1 - 0.39 11.3 2.3 3.6 8.2 1.4 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TraQ PF09679.10 KKK12307.1 - 0.04 13.8 0.0 0.12 12.3 0.0 1.8 2 0 0 2 2 2 0 Type-F conjugative transfer system pilin chaperone (TraQ) Peptidase_M20 PF01546.28 KKK12308.1 - 2.6e-24 86.1 0.0 5.4e-23 81.8 0.0 2.4 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 WD40 PF00400.32 KKK12308.1 - 6.1e-06 26.9 12.4 0.46 11.4 0.0 6.3 6 0 0 6 6 6 2 WD domain, G-beta repeat M20_dimer PF07687.14 KKK12308.1 - 7.9e-05 22.5 0.0 0.00016 21.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KKK12308.1 - 0.00016 21.5 0.0 0.00065 19.4 0.0 2.0 2 0 0 2 2 2 1 Peptidase family M28 ANAPC4_WD40 PF12894.7 KKK12308.1 - 0.0084 16.4 0.1 6 7.2 0.0 3.5 2 2 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 KKK12308.1 - 0.017 15.6 0.3 10 6.8 0.0 4.1 3 0 0 3 3 3 0 PQQ-like domain SpdB PF05122.13 KKK12308.1 - 0.098 12.8 1.3 0.16 12.1 0.1 2.0 2 0 0 2 2 2 0 Mobile element transfer protein DUF747 PF05346.11 KKK12309.1 - 7.8e-119 396.9 4.5 1e-118 396.4 4.5 1.2 1 0 0 1 1 1 1 Eukaryotic membrane protein family KCH PF16944.5 KKK12310.1 - 4.2e-99 331.4 3.6 5e-99 331.1 3.6 1.1 1 0 0 1 1 1 1 Fungal potassium channel FMO-like PF00743.19 KKK12311.1 - 1.8e-11 43.2 2.6 5.3e-09 35.0 0.2 3.0 1 1 1 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KKK12311.1 - 8.9e-11 41.6 0.0 7.1e-05 22.2 0.0 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KKK12311.1 - 2.1e-08 33.8 0.0 1.5e-06 27.7 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KKK12311.1 - 2.9e-08 33.8 0.0 8e-08 32.4 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KKK12311.1 - 1e-06 28.6 0.2 0.00015 21.5 0.1 2.4 2 1 0 2 2 2 2 FAD dependent oxidoreductase K_oxygenase PF13434.6 KKK12311.1 - 0.00023 20.4 0.1 0.11 11.6 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 KKK12311.1 - 0.0013 18.0 0.1 0.0023 17.2 0.1 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.6 KKK12311.1 - 0.0029 17.6 0.0 0.0096 15.9 0.0 1.9 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 KKK12311.1 - 0.015 14.4 0.1 0.023 13.8 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain Shikimate_DH PF01488.20 KKK12311.1 - 0.051 13.7 0.0 20 5.3 0.1 3.0 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase Pox_A_type_inc PF04508.12 KKK12312.1 - 0.0066 16.2 8.2 0.55 10.2 0.0 5.2 5 0 0 5 5 5 2 Viral A-type inclusion protein repeat Bcr-Abl_Oligo PF09036.10 KKK12312.1 - 0.056 13.5 1.8 1.6 8.8 0.0 3.1 2 0 0 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain Laminin_I PF06008.14 KKK12312.1 - 0.29 10.8 36.9 0.084 12.6 5.0 4.5 1 1 3 4 4 4 0 Laminin Domain I Corona_S2 PF01601.16 KKK12312.1 - 2 6.8 10.0 1.6 7.1 6.2 2.1 1 1 0 2 2 2 0 Coronavirus S2 glycoprotein DUF3496 PF12001.8 KKK12312.1 - 9 6.7 22.8 1.5 9.2 0.4 4.3 3 1 1 4 4 4 0 Domain of unknown function (DUF3496) DUF21 PF01595.20 KKK12313.1 - 7.1e-31 107.3 0.0 1.2e-30 106.5 0.0 1.3 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 KKK12313.1 - 1.6e-06 28.4 1.2 0.031 14.7 0.0 3.6 3 0 0 3 3 3 2 CBS domain Arginosuc_synth PF00764.19 KKK12314.1 - 2.2e-143 478.2 0.0 5e-143 477.1 0.0 1.5 1 1 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.13 KKK12314.1 - 2.3e-05 24.0 0.0 3.7e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 KKK12314.1 - 0.0054 15.6 0.0 0.0083 15.0 0.0 1.3 1 0 0 1 1 1 1 tRNA methyl transferase Asn_synthase PF00733.21 KKK12314.1 - 0.099 12.3 0.0 0.14 11.8 0.0 1.1 1 0 0 1 1 1 0 Asparagine synthase p450 PF00067.22 KKK12315.1 - 8.7e-74 248.9 0.0 1.1e-73 248.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 SGL PF08450.12 KKK12315.1 - 3.6e-30 105.3 0.0 6.6e-30 104.5 0.0 1.3 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Arylesterase PF01731.20 KKK12315.1 - 0.00014 21.9 0.0 0.00043 20.4 0.0 1.8 1 0 0 1 1 1 1 Arylesterase NHL PF01436.21 KKK12315.1 - 0.0099 15.9 0.7 0.24 11.5 0.0 2.7 2 0 0 2 2 2 1 NHL repeat Str_synth PF03088.16 KKK12315.1 - 0.19 11.9 0.0 0.75 10.0 0.0 2.0 2 1 0 2 2 2 0 Strictosidine synthase GST_N_2 PF13409.6 KKK12316.1 - 4.3e-09 36.5 0.0 1.1e-08 35.3 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KKK12316.1 - 1.7e-08 34.7 0.0 2e-07 31.2 0.0 2.2 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KKK12316.1 - 9.3e-07 29.2 0.0 1.7e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KKK12316.1 - 1.6e-06 28.3 0.0 2.5e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KKK12316.1 - 3.7e-06 27.0 0.0 6.9e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KKK12316.1 - 0.0021 18.0 0.1 0.004 17.1 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Asparaginase_2 PF01112.18 KKK12317.1 - 2.4e-11 43.2 0.6 2e-10 40.2 0.0 2.0 2 0 0 2 2 2 2 Asparaginase Tim17 PF02466.19 KKK12318.1 - 7.2e-32 110.1 8.7 9.3e-32 109.7 8.7 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family VMA21 PF09446.10 KKK12318.1 - 0.84 9.8 3.2 0.54 10.4 0.4 2.0 3 0 0 3 3 3 0 VMA21-like domain Zn_clus PF00172.18 KKK12319.1 - 6.3e-06 26.2 7.1 1.4e-05 25.1 7.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.12 KKK12319.1 - 2.3 8.7 5.3 22 5.6 0.7 2.4 2 0 0 2 2 2 0 Dickkopf N-terminal cysteine-rich region F-box-like PF12937.7 KKK12320.1 - 2.5e-05 24.1 0.2 5.8e-05 22.9 0.2 1.7 1 0 0 1 1 1 1 F-box-like Peptidase_M3 PF01432.20 KKK12341.1 - 3.8e-110 369.3 0.0 5e-110 368.9 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 Acetyltransf_17 PF17668.1 KKK12341.1 - 0.068 14.0 0.0 2.1 9.1 0.0 2.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Peptidase_M50B PF13398.6 KKK12341.1 - 0.16 11.6 0.2 0.29 10.7 0.2 1.3 1 0 0 1 1 1 0 Peptidase M50B-like FAM184 PF15665.5 KKK12342.1 - 6.3e-07 29.4 72.0 8.8e-06 25.6 37.2 7.2 1 1 5 7 7 7 4 Family with sequence similarity 184, A and B Pox_A_type_inc PF04508.12 KKK12342.1 - 0.00011 21.9 7.9 8 6.5 0.2 6.6 5 0 0 5 5 5 3 Viral A-type inclusion protein repeat Filament PF00038.21 KKK12342.1 - 0.002 17.8 166.4 0.11 12.1 27.8 8.9 1 1 6 8 8 8 4 Intermediate filament protein Spc7 PF08317.11 KKK12342.1 - 0.0038 16.2 21.5 0.0038 16.2 21.5 10.0 2 1 9 11 11 11 5 Spc7 kinetochore protein HIP1_clath_bdg PF16515.5 KKK12342.1 - 0.0084 16.7 11.8 0.0084 16.7 11.8 11.9 2 1 12 14 14 14 3 Clathrin-binding domain of Huntingtin-interacting protein 1 GRASP55_65 PF04495.14 KKK12343.1 - 4.4e-40 137.2 0.0 7.9e-37 126.7 0.0 2.2 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain PDZ_6 PF17820.1 KKK12343.1 - 0.0023 17.8 0.0 0.5 10.2 0.0 2.6 2 0 0 2 2 2 2 PDZ domain ApoO PF09769.9 KKK12344.1 - 7.9e-42 142.3 0.2 8.6e-41 138.9 0.1 2.0 2 0 0 2 2 2 1 Apolipoprotein O Mito_fiss_reg PF05308.11 KKK12344.1 - 7.6 6.5 9.8 13 5.8 9.8 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator DUF3591 PF12157.8 KKK12345.1 - 2.4e-178 593.3 0.0 3.1e-178 593.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) zf-CCHC PF00098.23 KKK12345.1 - 0.0051 16.8 0.7 0.0086 16.1 0.7 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 KKK12345.1 - 0.0063 16.3 1.2 0.016 15.1 1.2 1.7 1 0 0 1 1 1 1 Zinc knuckle Methyltransf_15 PF09445.10 KKK12346.1 - 8.5e-52 175.1 0.0 1.1e-51 174.7 0.0 1.1 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Met_10 PF02475.16 KKK12346.1 - 2.7e-12 46.8 0.0 3.6e-12 46.5 0.0 1.1 1 0 0 1 1 1 1 Met-10+ like-protein Cons_hypoth95 PF03602.15 KKK12346.1 - 4.6e-06 26.4 0.0 6.6e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 UPF0020 PF01170.18 KKK12346.1 - 6.6e-05 22.7 0.0 0.00011 21.9 0.0 1.5 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_18 PF12847.7 KKK12346.1 - 0.00012 22.0 0.0 0.00018 21.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKK12346.1 - 0.0035 18.0 0.0 0.0056 17.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KKK12346.1 - 0.042 14.5 0.0 0.07 13.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_5 PF01795.19 KKK12346.1 - 0.055 13.0 0.0 0.077 12.5 0.0 1.1 1 0 0 1 1 1 0 MraW methylase family DNA_methylase PF00145.17 KKK12346.1 - 0.12 11.7 0.0 0.23 10.8 0.0 1.5 1 1 0 1 1 1 0 C-5 cytosine-specific DNA methylase Methyltrans_SAM PF10672.9 KKK12346.1 - 0.18 10.9 0.0 0.26 10.4 0.0 1.1 1 0 0 1 1 1 0 S-adenosylmethionine-dependent methyltransferase Pkinase PF00069.25 KKK12347.1 - 2e-46 158.5 0.1 1.3e-23 83.7 0.0 3.3 3 0 0 3 3 3 2 Protein kinase domain FKBP_C PF00254.28 KKK12347.1 - 2.8e-31 107.7 0.0 6.5e-31 106.5 0.0 1.6 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase NPL PF17800.1 KKK12347.1 - 2.9e-31 108.1 0.4 8.7e-31 106.6 0.0 2.1 2 0 0 2 2 2 1 Nucleoplasmin-like domain Pkinase_Tyr PF07714.17 KKK12347.1 - 4.1e-19 68.9 0.0 8.9e-11 41.6 0.0 3.1 3 0 0 3 3 3 2 Protein tyrosine kinase APH PF01636.23 KKK12347.1 - 0.00016 21.7 0.4 0.00038 20.5 0.4 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family Noggin PF05806.12 KKK12347.1 - 5.9 6.7 6.0 2.4 8.0 0.0 2.7 2 0 0 2 2 2 0 Noggin PTPA PF03095.15 KKK12348.1 - 7.3e-118 393.4 0.0 8.4e-118 393.2 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein DUF572 PF04502.13 KKK12349.1 - 2.7e-19 70.0 6.8 3.2e-19 69.7 6.8 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) SgrR_N PF12793.7 KKK12349.1 - 0.085 13.1 0.6 0.85 9.9 0.2 2.2 2 0 0 2 2 2 0 Sugar transport-related sRNA regulator N-term SR-25 PF10500.9 KKK12349.1 - 4.1 6.9 18.6 20 4.7 18.7 2.1 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein APH PF01636.23 KKK12372.1 - 2.1e-08 34.4 0.9 6.6e-07 29.5 0.1 2.9 2 1 0 2 2 2 1 Phosphotransferase enzyme family Lectin_leg-like PF03388.13 KKK12373.1 - 3e-12 46.4 0.0 3.5e-12 46.1 0.0 1.1 1 0 0 1 1 1 1 Legume-like lectin family PRCC PF10253.9 KKK12374.1 - 5.1e-35 122.2 11.2 5.1e-35 122.2 11.2 3.5 2 2 1 3 3 3 1 Mitotic checkpoint regulator, MAD2B-interacting PRIMA1 PF16101.5 KKK12374.1 - 0.096 12.7 2.3 0.24 11.5 2.3 1.6 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 RR_TM4-6 PF06459.12 KKK12375.1 - 2.3 8.0 11.6 3.2 7.5 0.5 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Voltage_CLC PF00654.20 KKK12376.1 - 1.2e-69 235.2 23.2 1.7e-69 234.8 23.2 1.1 1 0 0 1 1 1 1 Voltage gated chloride channel CTK3 PF12243.8 KKK12376.1 - 7e-52 174.6 0.1 1.1e-51 173.9 0.1 1.3 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 CTK3_C PF12350.8 KKK12376.1 - 2.1e-18 66.3 8.1 5.1e-18 65.0 8.1 1.7 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 C-terminus AAA_5 PF07728.14 KKK12377.1 - 3e-129 425.7 0.7 7.6e-22 77.8 0.0 10.0 8 1 1 9 9 9 9 AAA domain (dynein-related subfamily) AAA_lid_7 PF17867.1 KKK12377.1 - 1.6e-49 166.6 6.7 5.8e-20 71.5 0.0 5.2 4 0 0 4 4 4 3 Midasin AAA lid domain AAA_lid_5 PF17865.1 KKK12377.1 - 8e-31 106.3 0.9 4.8e-30 103.8 0.0 3.0 4 0 0 4 4 1 1 Midasin AAA lid domain AAA_3 PF07726.11 KKK12377.1 - 1.7e-29 102.3 0.0 1.1e-10 41.5 0.0 7.7 8 0 0 8 8 7 3 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 KKK12377.1 - 1.1e-27 96.7 2.8 9.4e-05 22.0 0.0 7.4 7 0 0 7 7 7 6 P-loop containing dynein motor region AAA PF00004.29 KKK12377.1 - 7.6e-26 91.1 0.0 4.3e-05 23.9 0.0 7.3 6 0 0 6 6 6 5 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KKK12377.1 - 2.5e-25 89.8 11.2 0.00024 21.5 0.3 8.6 6 2 0 6 6 6 5 AAA ATPase domain Dynein_heavy PF03028.15 KKK12377.1 - 3.4e-22 78.8 0.0 7.7e-06 26.0 0.0 7.9 8 0 0 8 8 7 4 Dynein heavy chain region D6 P-loop domain AAA_30 PF13604.6 KKK12377.1 - 3.2e-18 66.1 0.0 0.0027 17.5 0.0 7.8 7 1 0 7 7 6 4 AAA domain AAA_14 PF13173.6 KKK12377.1 - 7.4e-17 61.6 0.0 0.0072 16.4 0.0 7.5 8 0 0 8 8 6 2 AAA domain AAA_33 PF13671.6 KKK12377.1 - 8.1e-17 61.7 0.1 0.0092 16.2 0.0 7.6 8 0 0 8 8 6 3 AAA domain AAA_6 PF12774.7 KKK12377.1 - 2.5e-16 59.5 0.0 0.024 13.6 0.1 7.6 8 0 0 8 8 7 3 Hydrolytic ATP binding site of dynein motor region AAA_22 PF13401.6 KKK12377.1 - 1e-15 58.2 2.5 0.066 13.5 0.0 7.9 8 0 0 8 8 6 4 AAA domain Sigma54_activat PF00158.26 KKK12377.1 - 3.1e-15 56.3 0.0 0.0091 15.7 0.1 6.3 6 0 0 6 6 6 3 Sigma-54 interaction domain AAA_18 PF13238.6 KKK12377.1 - 3.4e-15 56.7 1.6 0.13 12.8 0.0 7.6 6 0 0 6 6 6 2 AAA domain ABC_tran PF00005.27 KKK12377.1 - 5.2e-15 56.2 2.1 0.049 14.2 0.0 7.0 7 0 0 7 7 7 3 ABC transporter TsaE PF02367.17 KKK12377.1 - 1.6e-14 53.9 3.2 0.056 13.5 0.0 6.5 6 0 0 6 6 6 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zeta_toxin PF06414.12 KKK12377.1 - 2e-12 46.8 2.1 1.5 8.0 0.0 7.5 8 0 0 8 8 6 1 Zeta toxin Mg_chelatase PF01078.21 KKK12377.1 - 7.3e-12 45.1 3.3 3.7 6.9 0.1 9.2 9 1 0 9 9 9 0 Magnesium chelatase, subunit ChlI NACHT PF05729.12 KKK12377.1 - 2.2e-11 44.0 5.4 0.11 12.4 0.1 5.3 4 0 0 4 4 4 3 NACHT domain RNA_helicase PF00910.22 KKK12377.1 - 3.5e-11 43.4 1.6 1.3 9.5 0.0 6.7 6 0 0 6 6 6 2 RNA helicase RsgA_GTPase PF03193.16 KKK12377.1 - 1.5e-10 41.2 1.6 0.18 11.7 0.1 6.4 6 0 0 6 6 6 2 RsgA GTPase RuvB_N PF05496.12 KKK12377.1 - 1.9e-10 40.7 3.8 0.08 12.7 0.0 7.0 7 0 0 7 7 7 2 Holliday junction DNA helicase RuvB P-loop domain Sigma54_activ_2 PF14532.6 KKK12377.1 - 3e-10 40.3 1.2 0.0015 18.6 0.1 5.5 6 0 0 6 6 4 2 Sigma-54 interaction domain SRP54 PF00448.22 KKK12377.1 - 1.1e-09 38.2 5.7 0.061 12.9 0.0 5.9 6 0 0 6 6 6 2 SRP54-type protein, GTPase domain Rad17 PF03215.15 KKK12377.1 - 3.6e-09 36.8 1.1 0.76 9.7 0.0 5.7 5 0 0 5 5 5 1 Rad17 P-loop domain AAA_29 PF13555.6 KKK12377.1 - 3.9e-09 36.1 2.1 1.9 8.3 0.0 6.6 6 0 0 6 6 6 1 P-loop containing region of AAA domain DUF815 PF05673.13 KKK12377.1 - 4.6e-09 35.8 1.7 0.26 10.4 0.1 5.7 6 0 0 6 6 6 2 Protein of unknown function (DUF815) PduV-EutP PF10662.9 KKK12377.1 - 9e-09 35.2 5.5 0.061 13.1 0.0 6.0 6 0 0 6 6 6 2 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.23 KKK12377.1 - 9e-09 35.4 3.2 0.18 11.9 0.0 6.5 6 0 0 6 6 6 1 50S ribosome-binding GTPase T2SSE PF00437.20 KKK12377.1 - 2.5e-08 33.3 3.9 0.22 10.5 0.0 6.1 6 0 0 6 6 6 1 Type II/IV secretion system protein AAA_25 PF13481.6 KKK12377.1 - 3.2e-08 33.4 6.1 1.6 8.2 0.0 6.4 6 1 0 6 6 5 2 AAA domain AAA_19 PF13245.6 KKK12377.1 - 4.9e-08 33.4 11.4 0.75 10.1 0.2 7.4 8 0 0 8 8 5 2 AAA domain ATPase_2 PF01637.18 KKK12377.1 - 6.3e-08 32.8 0.0 17 5.3 0.0 6.5 6 0 0 6 6 6 0 ATPase domain predominantly from Archaea TniB PF05621.11 KKK12377.1 - 7.1e-08 32.1 3.5 0.62 9.4 0.0 7.1 8 0 0 8 8 7 1 Bacterial TniB protein AAA_28 PF13521.6 KKK12377.1 - 1.8e-07 31.5 9.6 0.048 13.9 0.2 6.4 6 1 0 6 6 5 1 AAA domain Roc PF08477.13 KKK12377.1 - 2.5e-07 30.9 3.3 6.4 7.0 0.1 6.4 6 0 0 6 6 6 0 Ras of Complex, Roc, domain of DAPkinase MCM PF00493.23 KKK12377.1 - 5.9e-07 28.8 0.1 0.75 8.8 0.0 5.3 6 0 0 6 6 5 1 MCM P-loop domain AAA_24 PF13479.6 KKK12377.1 - 8.5e-07 28.9 0.2 1.6 8.4 0.0 6.2 7 0 0 7 7 5 1 AAA domain Bac_DnaA PF00308.18 KKK12377.1 - 2.4e-06 27.5 0.1 0.4 10.5 0.0 4.1 4 0 0 4 4 3 1 Bacterial dnaA protein IstB_IS21 PF01695.17 KKK12377.1 - 6.3e-06 26.0 0.1 4.9 6.9 0.0 5.3 5 0 0 5 5 5 0 IstB-like ATP binding protein SRPRB PF09439.10 KKK12377.1 - 7.3e-06 25.5 1.9 4.5 6.7 0.0 5.7 6 0 0 6 6 5 0 Signal recognition particle receptor beta subunit Viral_helicase1 PF01443.18 KKK12377.1 - 2.8e-05 24.0 0.0 0.39 10.4 0.0 4.7 4 0 0 4 4 4 1 Viral (Superfamily 1) RNA helicase AAA_9 PF12781.7 KKK12377.1 - 2.9e-05 23.3 0.0 0.39 9.8 0.0 4.0 4 0 0 4 4 4 2 ATP-binding dynein motor region CbiA PF01656.23 KKK12377.1 - 3.3e-05 23.9 0.1 4.5 7.4 0.0 4.6 4 0 0 4 4 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain NTPase_1 PF03266.15 KKK12377.1 - 3.6e-05 23.8 7.8 0.53 10.2 0.1 5.2 5 0 0 5 5 4 1 NTPase ATP_bind_1 PF03029.17 KKK12377.1 - 4e-05 23.5 2.5 2.9 7.6 0.0 5.6 5 0 0 5 5 5 0 Conserved hypothetical ATP binding protein AAA_8 PF12780.7 KKK12377.1 - 0.00019 20.8 0.7 2.3 7.5 0.0 5.3 6 0 0 6 6 5 1 P-loop containing dynein motor region D4 TIP49 PF06068.13 KKK12377.1 - 0.00023 20.5 4.2 0.15 11.3 0.0 5.1 6 0 0 6 6 6 1 TIP49 P-loop domain NB-ARC PF00931.22 KKK12377.1 - 0.00041 19.6 1.9 16 4.6 0.1 5.1 5 0 0 5 5 5 0 NB-ARC domain ResIII PF04851.15 KKK12377.1 - 0.0005 20.1 0.9 6 6.8 0.2 4.8 5 0 0 5 5 4 0 Type III restriction enzyme, res subunit CPT PF07931.12 KKK12377.1 - 0.00068 19.5 1.4 3.5 7.4 0.0 5.5 6 1 0 6 6 4 0 Chloramphenicol phosphotransferase-like protein FeoB_N PF02421.18 KKK12377.1 - 0.0052 16.3 6.1 2.5 7.6 0.0 5.4 6 0 0 6 6 5 1 Ferrous iron transport protein B ATPase PF06745.13 KKK12377.1 - 0.0068 15.8 0.4 37 3.6 0.0 4.7 5 0 0 5 5 5 0 KaiC G-alpha PF00503.20 KKK12377.1 - 0.011 14.9 0.5 11 5.0 0.0 4.6 5 0 0 5 5 4 0 G-protein alpha subunit MobB PF03205.14 KKK12377.1 - 0.018 14.9 9.3 4.5 7.2 0.1 5.8 6 0 0 6 6 6 0 Molybdopterin guanine dinucleotide synthesis protein B Septin PF00735.18 KKK12377.1 - 0.044 13.0 1.8 8 5.6 0.1 3.7 5 0 0 5 5 4 0 Septin MeaB PF03308.16 KKK12377.1 - 0.057 12.4 7.9 0.38 9.7 0.4 4.1 5 0 0 5 5 5 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DAP3 PF10236.9 KKK12377.1 - 0.059 12.5 4.8 6.4 5.8 0.2 4.3 5 0 0 5 5 5 0 Mitochondrial ribosomal death-associated protein 3 PRK PF00485.18 KKK12377.1 - 0.061 13.0 0.1 6.4 6.5 0.0 3.6 4 0 0 4 4 3 0 Phosphoribulokinase / Uridine kinase family KTI12 PF08433.10 KKK12377.1 - 0.14 11.6 0.9 25 4.2 0.0 4.2 4 0 0 4 4 3 0 Chromatin associated protein KTI12 Thymidylate_kin PF02223.17 KKK12377.1 - 0.21 11.2 2.0 64 3.1 0.0 4.9 5 0 0 5 5 4 0 Thymidylate kinase TrwB_AAD_bind PF10412.9 KKK12377.1 - 0.29 10.0 2.6 8.3 5.2 0.2 3.8 4 0 0 4 4 4 0 Type IV secretion-system coupling protein DNA-binding domain DnaB_C PF03796.15 KKK12377.1 - 0.56 9.5 5.7 2.1 7.6 0.0 4.0 4 0 0 4 4 3 0 DnaB-like helicase C terminal domain dNK PF01712.19 KKK12377.1 - 0.62 9.9 3.7 24 4.7 0.1 4.1 4 0 0 4 4 4 0 Deoxynucleoside kinase cobW PF02492.19 KKK12377.1 - 1.8 8.1 14.7 13 5.4 0.0 5.7 7 0 0 7 7 6 0 CobW/HypB/UreG, nucleotide-binding domain Ras PF00071.22 KKK12377.1 - 5.7 6.5 5.2 1.1e+02 2.4 0.1 4.1 4 0 0 4 4 4 0 Ras family DUF155 PF02582.14 KKK12378.1 - 1.4e-51 175.0 0.1 2.5e-51 174.3 0.1 1.4 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 U3_snoRNA_assoc PF08297.11 KKK12378.1 - 1.2e-20 74.0 1.6 1.2e-20 74.0 1.6 4.0 4 0 0 4 4 4 1 U3 snoRNA associated UPF0449 PF15136.6 KKK12378.1 - 0.099 13.1 6.0 0.28 11.7 0.0 3.5 3 0 0 3 3 3 0 Uncharacterised protein family UPF0449 adh_short PF00106.25 KKK12379.1 - 1.1e-39 136.0 0.8 1.4e-39 135.6 0.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KKK12379.1 - 1.2e-30 106.8 0.3 1.5e-30 106.5 0.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 KKK12379.1 - 1.7e-08 34.6 0.0 3.1e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KKK12379.1 - 0.00022 20.8 0.0 0.00033 20.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KKK12379.1 - 0.023 14.2 0.0 0.038 13.6 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family DER1 PF04511.15 KKK12379.1 - 0.028 14.4 0.0 0.047 13.6 0.0 1.4 1 0 0 1 1 1 0 Der1-like family RmlD_sub_bind PF04321.17 KKK12379.1 - 0.058 12.5 0.0 0.089 11.9 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain PAE PF03283.13 KKK12379.1 - 0.068 12.3 0.1 0.096 11.8 0.1 1.2 1 0 0 1 1 1 0 Pectinacetylesterase TadZ_N PF16968.5 KKK12379.1 - 0.075 12.7 0.3 0.14 11.9 0.3 1.3 1 0 0 1 1 1 0 Pilus assembly protein TadZ N-terminal GDP_Man_Dehyd PF16363.5 KKK12379.1 - 0.17 11.2 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase CENP-T_C PF15511.6 KKK12394.1 - 4.4e-09 36.4 0.1 5.3e-09 36.2 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 KKK12394.1 - 1.9e-05 25.1 0.2 2.2e-05 24.8 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.17 KKK12394.1 - 5e-05 23.4 0.2 7.3e-05 22.9 0.2 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 KKK12394.1 - 0.00012 22.3 0.1 0.00021 21.5 0.1 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 KKK12394.1 - 0.00017 21.9 0.1 0.00023 21.5 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 KKK12394.1 - 0.0038 17.3 0.0 0.0045 17.0 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 KKK12394.1 - 0.0045 17.0 0.0 0.0054 16.7 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated UPF0137 PF03677.13 KKK12394.1 - 0.05 13.4 0.2 0.061 13.1 0.2 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) TFIID_20kDa PF03847.13 KKK12394.1 - 0.059 13.9 0.0 0.12 12.9 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A HIGH_NTase1_ass PF16581.5 KKK12394.1 - 0.073 13.1 0.0 0.082 12.9 0.0 1.1 1 0 0 1 1 1 0 Cytidyltransferase-related C-terminal region Lipase_GDSL_2 PF13472.6 KKK12395.1 - 1.2e-18 68.1 0.3 1.9e-18 67.5 0.3 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KKK12395.1 - 4.9e-08 33.2 0.1 1.4e-07 31.7 0.1 1.8 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase OSK PF17182.4 KKK12395.1 - 0.0003 20.1 0.1 0.00062 19.1 0.1 1.4 1 1 0 1 1 1 1 OSK domain 2-ph_phosp PF04029.14 KKK12395.1 - 0.12 11.5 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 2-phosphosulpholactate phosphatase CBM_21 PF03370.13 KKK12396.1 - 9.3e-35 119.2 2.9 1.5e-34 118.5 2.9 1.3 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 KKK12396.1 - 1.1e-10 41.9 5.4 2.1e-10 41.1 5.4 1.4 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) WD40 PF00400.32 KKK12397.1 - 0.0005 20.8 5.1 16 6.5 0.0 6.1 6 0 0 6 6 6 2 WD domain, G-beta repeat Lactonase PF10282.9 KKK12397.1 - 0.018 14.3 0.0 0.1 11.8 0.0 2.0 2 0 0 2 2 2 0 Lactonase, 7-bladed beta-propeller Nucleoporin_FG PF13634.6 KKK12398.1 - 5.6e-06 27.1 81.8 0.0097 16.7 42.8 3.5 1 1 2 3 3 3 3 Nucleoporin FG repeat region DUF1664 PF07889.12 KKK12398.1 - 0.03 14.4 0.2 1.6 8.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Lectin_N PF03954.14 KKK12398.1 - 0.076 12.8 0.1 3.5 7.4 0.0 2.5 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain TrwC PF08751.11 KKK12398.1 - 0.087 12.3 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 TrwC relaxase DUF533 PF04391.12 KKK12398.1 - 3.5 7.2 5.5 8.7 5.9 5.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF533) Annexin PF00191.20 KKK12399.1 - 1.9e-59 197.6 2.3 1.1e-17 63.8 0.0 4.1 4 0 0 4 4 4 4 Annexin DUF5617 PF18493.1 KKK12399.1 - 0.15 12.2 0.1 0.5 10.5 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5617) Acetyltransf_11 PF13720.6 KKK12399.1 - 0.63 10.5 2.1 52 4.4 0.1 3.6 4 0 0 4 4 4 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 Mito_carr PF00153.27 KKK12400.1 - 4e-38 129.2 8.5 1.6e-15 56.8 0.0 4.1 4 0 0 4 4 3 3 Mitochondrial carrier protein zf-RING_UBOX PF13445.6 KKK12400.1 - 1.1e-07 31.7 4.9 1.1e-07 31.7 4.9 2.3 2 0 0 2 2 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KKK12400.1 - 2.9e-07 30.2 5.4 2.9e-07 30.2 5.4 3.8 4 1 0 4 4 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KKK12400.1 - 3.4e-07 30.0 3.2 3.4e-07 30.0 3.2 3.4 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 KKK12400.1 - 1.7e-06 27.8 0.7 1.7e-06 27.8 0.7 2.7 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-RING_2 PF13639.6 KKK12400.1 - 2.3e-06 27.8 6.2 2.3e-06 27.8 6.2 4.1 4 0 0 4 4 1 1 Ring finger domain zf-RING_5 PF14634.6 KKK12400.1 - 8.2e-05 22.5 4.6 8.2e-05 22.5 4.6 5.3 5 1 1 6 6 4 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KKK12400.1 - 0.00021 21.4 7.8 0.00021 21.4 7.8 3.3 3 0 0 3 3 2 1 zinc finger of C3HC4-type, RING SH3_9 PF14604.6 KKK12400.1 - 0.00022 21.0 0.1 0.0011 18.8 0.2 2.2 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 KKK12400.1 - 0.001 18.7 0.2 0.0021 17.6 0.2 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KKK12400.1 - 0.0062 16.2 0.3 0.022 14.5 0.1 2.0 2 0 0 2 2 2 1 Variant SH3 domain Tmpp129 PF10272.9 KKK12400.1 - 0.1 11.9 3.7 0.21 10.9 3.7 1.4 1 0 0 1 1 1 0 Putative transmembrane protein precursor DUF883 PF05957.13 KKK12400.1 - 0.28 11.8 4.5 0.17 12.5 0.3 3.0 2 0 0 2 2 1 0 Bacterial protein of unknown function (DUF883) Fip1 PF05182.13 KKK12402.1 - 4.2e-20 71.0 2.2 7.4e-20 70.2 2.2 1.4 1 0 0 1 1 1 1 Fip1 motif Cpn10 PF00166.21 KKK12402.1 - 2.5e-15 56.3 0.0 4e-07 30.0 0.0 2.4 1 1 1 2 2 2 2 Chaperonin 10 Kd subunit Ribosomal_60s PF00428.19 KKK12402.1 - 0.76 10.4 5.6 1.3 9.7 3.6 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein Rpr2 PF04032.16 KKK12403.1 - 8.9e-11 41.9 0.7 8.9e-11 41.9 0.7 1.7 2 0 0 2 2 2 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain DZR PF12773.7 KKK12403.1 - 0.077 13.0 1.4 0.14 12.2 1.4 1.4 1 0 0 1 1 1 0 Double zinc ribbon LAT PF15234.6 KKK12403.1 - 0.78 9.4 5.8 0.2 11.3 2.1 1.8 2 0 0 2 2 2 0 Linker for activation of T-cells GFA PF04828.14 KKK12403.1 - 0.8 10.1 3.7 0.6 10.5 0.2 2.2 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme DBR1 PF05011.13 KKK12404.1 - 5.2e-47 159.8 2.2 1.2e-45 155.4 0.0 2.6 2 0 0 2 2 2 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.28 KKK12404.1 - 1e-07 32.7 0.2 2.2e-07 31.6 0.2 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase RTP1_C1 PF10363.9 KKK12405.1 - 2.2e-30 105.1 0.8 9.4e-30 103.1 0.1 2.4 2 0 0 2 2 2 1 Required for nuclear transport of RNA pol II C-terminus 1 RTP1_C2 PF10304.9 KKK12405.1 - 7.2e-09 35.2 0.0 1.8e-08 33.9 0.0 1.8 1 0 0 1 1 1 1 Required for nuclear transport of RNA pol II C-terminus 2 HEAT_EZ PF13513.6 KKK12405.1 - 0.0054 17.2 0.7 1.9 9.1 0.0 3.8 3 0 0 3 3 3 1 HEAT-like repeat M20_dimer PF07687.14 KKK12405.1 - 0.11 12.4 0.0 0.44 10.5 0.0 2.0 1 0 0 1 1 1 0 Peptidase dimerisation domain zf-ZPR1 PF03367.13 KKK12406.1 - 2.4e-105 349.3 0.1 1.2e-53 181.2 0.0 2.2 2 0 0 2 2 2 2 ZPR1 zinc-finger domain Paired_CXXCH_1 PF09699.10 KKK12406.1 - 0.033 13.9 0.5 3.9 7.3 0.0 2.5 2 0 0 2 2 2 0 Doubled CXXCH motif (Paired_CXXCH_1) Cytochrome_C7 PF14522.6 KKK12406.1 - 0.081 12.9 0.2 0.081 12.9 0.2 2.4 2 1 0 2 2 2 0 Cytochrome c7 and related cytochrome c zinc-ribbons_6 PF07191.12 KKK12406.1 - 0.21 11.6 2.4 3.3 7.8 0.2 2.5 2 0 0 2 2 2 0 zinc-ribbons TIP120 PF08623.10 KKK12407.1 - 1.4e-62 210.4 0.1 6.1e-62 208.3 0.0 2.2 2 0 0 2 2 2 1 TATA-binding protein interacting (TIP20) HEAT PF02985.22 KKK12407.1 - 3.3e-11 42.5 8.4 0.076 13.3 0.0 8.7 9 0 0 9 9 9 3 HEAT repeat HEAT_2 PF13646.6 KKK12407.1 - 3.2e-05 24.2 9.0 3.2 8.2 0.0 7.1 5 2 2 7 7 7 2 HEAT repeats Arm PF00514.23 KKK12407.1 - 4e-05 23.5 0.4 2 8.5 0.0 5.1 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 KKK12407.1 - 0.0001 22.7 8.3 1.6 9.4 0.0 7.3 6 1 1 7 7 7 1 HEAT-like repeat TAF6_C PF07571.13 KKK12407.1 - 0.053 13.9 0.1 1.7 9.0 0.0 3.4 2 1 0 3 3 3 0 TAF6 C-terminal HEAT repeat domain ParcG PF10274.9 KKK12407.1 - 0.054 13.6 0.8 39 4.3 0.0 3.6 2 1 1 3 3 3 0 Parkin co-regulated protein Spectrin_like PF18373.1 KKK12407.1 - 0.098 12.7 0.1 0.34 11.0 0.1 1.9 1 0 0 1 1 1 0 Spectrin like domain LRR_4 PF12799.7 KKK12408.1 - 1.7e-24 85.5 44.1 8.1e-06 26.1 1.5 8.6 7 1 1 8 8 8 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KKK12408.1 - 5.1e-24 83.8 44.6 1.1e-08 34.6 1.2 7.3 4 2 4 8 8 8 7 Leucine rich repeat LRR_1 PF00560.33 KKK12408.1 - 6.4e-06 26.0 25.9 6.9 7.6 0.1 10.4 8 2 0 8 8 8 2 Leucine Rich Repeat LRR_9 PF14580.6 KKK12408.1 - 2.6e-05 23.8 12.6 0.06 12.9 0.0 4.3 1 1 3 4 4 4 4 Leucine-rich repeat LRR_6 PF13516.6 KKK12408.1 - 0.0032 17.4 32.1 0.57 10.4 0.0 10.1 11 0 0 11 11 11 4 Leucine Rich repeat WD40 PF00400.32 KKK12409.1 - 1.6e-13 50.9 4.6 0.0078 17.0 0.5 5.5 5 0 0 5 5 5 4 WD domain, G-beta repeat SGL PF08450.12 KKK12409.1 - 0.0098 15.5 0.0 0.1 12.1 0.0 2.1 1 1 1 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region ANAPC4_WD40 PF12894.7 KKK12409.1 - 0.049 13.9 0.0 18 5.7 0.0 3.6 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain SARS_X4 PF08779.10 KKK12409.1 - 0.13 12.5 0.0 1.9 8.7 0.0 2.5 2 0 0 2 2 2 0 SARS coronavirus X4 like ATP_bind_1 PF03029.17 KKK12410.1 - 1.4e-75 254.2 0.0 1.8e-75 253.9 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_31 PF13614.6 KKK12410.1 - 0.0014 18.5 0.0 2.2 8.1 0.0 2.3 1 1 0 2 2 2 2 AAA domain MeaB PF03308.16 KKK12410.1 - 0.0015 17.5 0.0 0.0033 16.4 0.0 1.4 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB MMR_HSR1 PF01926.23 KKK12410.1 - 0.0041 17.2 0.0 0.034 14.2 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_33 PF13671.6 KKK12410.1 - 0.014 15.6 0.0 0.051 13.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 KKK12410.1 - 0.055 13.7 0.0 0.12 12.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain CLP1_P PF16575.5 KKK12410.1 - 0.058 13.2 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_10 PF12846.7 KKK12410.1 - 0.063 12.2 0.0 0.095 11.6 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain Fer4_NifH PF00142.18 KKK12410.1 - 0.15 11.5 0.3 0.43 10.0 0.3 1.8 1 1 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family RNA_helicase PF00910.22 KKK12410.1 - 0.17 12.3 0.0 0.35 11.3 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_17 PF13207.6 KKK12410.1 - 0.28 11.6 0.1 0.28 11.6 0.1 2.3 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.6 KKK12410.1 - 0.35 11.4 2.4 0.51 10.9 0.1 2.2 2 1 0 2 2 2 0 AAA domain RRN3 PF05327.11 KKK12410.1 - 1.2 7.6 3.9 1.8 7.0 3.9 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 ThiF PF00899.21 KKK12411.1 - 9.8e-13 48.0 0.0 4.4e-12 45.9 0.0 2.2 1 1 0 1 1 1 1 ThiF family E1_4HB PF16191.5 KKK12411.1 - 0.053 13.7 0.1 0.48 10.7 0.0 2.6 2 1 0 2 2 2 0 Ubiquitin-activating enzyme E1 four-helix bundle BshC PF10079.9 KKK12411.1 - 0.13 11.0 0.0 0.19 10.5 0.0 1.1 1 0 0 1 1 1 0 Bacillithiol biosynthesis BshC RuvA_C PF07499.13 KKK12411.1 - 0.18 12.3 0.4 1 9.8 0.0 2.6 3 0 0 3 3 3 0 RuvA, C-terminal domain Rib_5-P_isom_A PF06026.14 KKK12412.1 - 5e-44 149.9 0.0 8e-44 149.3 0.0 1.3 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.22 KKK12412.1 - 0.0024 17.8 0.1 1.7 8.6 0.0 2.2 1 1 0 2 2 2 2 DeoR C terminal sensor domain Citrate_bind PF16114.5 KKK12413.1 - 5.7e-88 293.1 0.0 8.2e-88 292.5 0.0 1.2 1 0 0 1 1 1 1 ATP citrate lyase citrate-binding ATP-grasp_2 PF08442.10 KKK12413.1 - 1.3e-08 34.6 0.0 2e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain Reovirus_M2 PF05993.12 KKK12413.1 - 0.056 11.6 0.1 0.084 11.0 0.1 1.1 1 0 0 1 1 1 0 Reovirus major virion structural protein Mu-1/Mu-1C (M2) XAP5 PF04921.14 KKK12414.1 - 8.3e-64 215.8 0.1 3.1e-63 213.9 0.0 1.9 2 0 0 2 2 2 1 XAP5, circadian clock regulator DUF4604 PF15377.6 KKK12414.1 - 0.0041 17.6 6.0 0.0041 17.6 6.0 2.5 3 0 0 3 3 3 1 Domain of unknown function (DUF4604) DHC_N2 PF08393.13 KKK12414.1 - 0.017 14.2 0.9 0.028 13.5 0.9 1.2 1 0 0 1 1 1 0 Dynein heavy chain, N-terminal region 2 DUF5082 PF16888.5 KKK12414.1 - 0.02 15.2 1.0 0.051 13.9 1.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) Exonuc_VII_L PF02601.15 KKK12414.1 - 0.03 13.9 0.2 0.055 13.0 0.2 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit Mod_r PF07200.13 KKK12414.1 - 0.068 13.3 5.6 0.23 11.6 5.6 1.9 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein FTCD_C PF04961.12 KKK12414.1 - 0.083 12.7 1.3 0.16 11.7 1.3 1.5 1 0 0 1 1 1 0 Formiminotransferase-cyclodeaminase SLATT_6 PF18169.1 KKK12414.1 - 0.15 11.7 0.8 0.25 10.9 0.8 1.3 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 6 Syntaxin_2 PF14523.6 KKK12414.1 - 0.24 11.8 5.6 0.62 10.5 5.6 1.7 1 0 0 1 1 1 0 Syntaxin-like protein Nup54 PF13874.6 KKK12414.1 - 0.38 10.9 5.0 1.7 8.8 3.8 2.3 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 Fib_alpha PF08702.10 KKK12414.1 - 0.4 10.9 5.6 0.93 9.7 5.6 1.5 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family GAGA_bind PF06217.12 KKK12414.1 - 5.3 7.2 8.9 11 6.2 2.0 2.8 2 1 0 2 2 2 0 GAGA binding protein-like family ZapB PF06005.12 KKK12414.1 - 8.9 6.8 12.1 3.9 8.0 7.4 2.7 2 1 0 2 2 1 0 Cell division protein ZapB IFT57 PF10498.9 KKK12414.1 - 9.5 5.1 14.3 0.14 11.1 6.2 1.8 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 RNase_P_Rpp14 PF01900.19 KKK12415.1 - 8.9e-37 125.5 0.0 1.2e-36 125.0 0.0 1.2 1 0 0 1 1 1 1 Rpp14/Pop5 family CoA_binding PF02629.19 KKK12416.1 - 4.7e-19 68.9 0.0 1.8e-18 67.0 0.0 2.1 2 0 0 2 2 2 1 CoA binding domain Citrate_synt PF00285.21 KKK12416.1 - 4.9e-18 65.3 0.1 1.9e-15 56.8 0.1 2.8 1 1 1 2 2 2 2 Citrate synthase, C-terminal domain Ligase_CoA PF00549.19 KKK12416.1 - 3.7e-15 56.1 0.1 6.5e-15 55.3 0.1 1.4 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 KKK12416.1 - 8.7e-07 28.8 0.0 5.6e-06 26.2 0.0 2.2 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain RRM_1 PF00076.22 KKK12462.1 - 3.1e-16 58.9 0.0 5.6e-16 58.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF5486 PF17588.2 KKK12462.1 - 0.21 11.5 1.0 0.42 10.5 1.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5486) NARP1 PF12569.8 KKK12462.1 - 5.2 5.9 6.0 7.1 5.4 6.0 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Sec2p PF06428.11 KKK12463.1 - 3.7e-09 36.4 11.0 3.7e-09 36.4 11.0 3.0 3 0 0 3 3 3 1 GDP/GTP exchange factor Sec2p bZIP_1 PF00170.21 KKK12463.1 - 0.004 17.2 12.8 0.036 14.2 0.2 3.3 2 1 1 3 3 3 2 bZIP transcription factor TFIIA PF03153.13 KKK12463.1 - 0.023 14.7 25.5 0.028 14.4 25.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Jnk-SapK_ap_N PF09744.9 KKK12463.1 - 0.075 13.3 28.7 0.39 10.9 12.8 3.1 3 0 0 3 3 3 0 JNK_SAPK-associated protein-1 SlyX PF04102.12 KKK12463.1 - 0.43 11.2 0.1 0.43 11.2 0.1 4.1 3 1 1 4 4 4 0 SlyX Vac_Fusion PF02346.16 KKK12463.1 - 0.55 9.9 6.8 4 7.1 2.5 2.7 2 0 0 2 2 2 0 Chordopoxvirus multifunctional envelope protein A27 FAM76 PF16046.5 KKK12463.1 - 6.6 6.0 14.0 34 3.6 12.8 2.1 2 0 0 2 2 2 0 FAM76 protein MFS_1 PF07690.16 KKK12464.1 - 1.2e-44 152.7 43.3 6.1e-35 120.8 18.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KKK12464.1 - 7.3e-07 27.9 2.7 2.6e-05 22.7 1.4 3.0 2 1 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family MFS_3 PF05977.13 KKK12464.1 - 1.2e-06 27.2 13.8 7.1e-06 24.7 3.2 2.5 2 0 0 2 2 2 2 Transmembrane secretion effector PUCC PF03209.15 KKK12464.1 - 4.6e-06 25.9 1.1 4.6e-06 25.9 1.1 2.4 2 0 0 2 2 2 1 PUCC protein MFS_4 PF06779.14 KKK12464.1 - 0.0083 15.5 27.5 0.37 10.0 1.9 3.9 2 2 1 3 3 3 2 Uncharacterised MFS-type transporter YbfB NAD4L PF06235.11 KKK12464.1 - 0.014 15.4 0.3 0.014 15.4 0.3 2.6 2 0 0 2 2 2 0 NADH dehydrogenase subunit 4L (NAD4L) PseudoU_synth_2 PF00849.22 KKK12465.1 - 1.1e-25 90.5 0.0 1.7e-25 89.9 0.0 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase FAD_binding_4 PF01565.23 KKK12465.1 - 5.5e-22 78.0 2.6 1e-21 77.1 2.6 1.5 1 0 0 1 1 1 1 FAD binding domain S4 PF01479.25 KKK12465.1 - 0.0049 16.6 0.1 0.011 15.4 0.1 1.6 1 0 0 1 1 1 1 S4 domain ADK_lid PF05191.14 KKK12465.1 - 0.062 13.3 0.6 1.4 9.0 0.0 2.5 2 0 0 2 2 2 0 Adenylate kinase, active site lid Ribosomal_L32e PF01655.18 KKK12466.1 - 2.9e-49 166.0 0.6 7.1e-49 164.7 0.6 1.7 1 0 0 1 1 1 1 Ribosomal protein L32 GFO_IDH_MocA PF01408.22 KKK12466.1 - 1e-16 61.8 0.0 2.7e-16 60.5 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KKK12466.1 - 0.0014 18.7 0.0 0.0031 17.5 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain 4HBT PF03061.22 KKK12468.1 - 2.1e-13 50.4 0.0 2.8e-13 50.0 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_2 PF13279.6 KKK12468.1 - 9.1e-05 22.9 0.0 0.00012 22.5 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl-ACP_TE PF01643.17 KKK12468.1 - 0.00045 19.6 0.3 0.00068 19.0 0.3 1.2 1 0 0 1 1 1 1 Acyl-ACP thioesterase ILVD_EDD PF00920.21 KKK12469.1 - 3.2e-109 365.9 0.0 3.7e-109 365.7 0.0 1.0 1 0 0 1 1 1 1 Dehydratase family DHHA1 PF02272.19 KKK12471.1 - 0.013 15.9 0.1 0.013 15.9 0.1 1.0 1 0 0 1 1 1 0 DHHA1 domain RuBisCO_small PF00101.20 KKK12471.1 - 0.07 13.1 0.0 0.071 13.1 0.0 1.1 1 0 0 1 1 1 0 Ribulose bisphosphate carboxylase, small chain CH PF00307.31 KKK12493.1 - 1.3e-13 51.1 0.0 2.3e-13 50.3 0.0 1.5 1 0 0 1 1 1 1 Calponin homology (CH) domain CDC24 PF06395.11 KKK12493.1 - 0.14 12.4 0.0 0.27 11.5 0.0 1.4 1 0 0 1 1 1 0 CDC24 Calponin CAMSAP_CH PF11971.8 KKK12493.1 - 0.15 12.0 0.0 0.32 10.9 0.0 1.5 1 0 0 1 1 1 0 CAMSAP CH domain ORMDL PF04061.14 KKK12494.1 - 7.6e-59 197.4 3.7 8.9e-59 197.2 3.7 1.0 1 0 0 1 1 1 1 ORMDL family DUF819 PF05684.12 KKK12495.1 - 0.21 10.6 0.0 0.34 9.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF819) Menin PF05053.13 KKK12495.1 - 1.9 6.7 4.7 2.7 6.2 4.7 1.1 1 0 0 1 1 1 0 Menin ArfGap PF01412.18 KKK12497.1 - 8.2e-40 135.5 0.3 1.2e-39 135.0 0.3 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf SelR PF01641.18 KKK12498.1 - 2.9e-50 169.4 0.1 3.7e-50 169.0 0.1 1.1 1 0 0 1 1 1 1 SelR domain Yippee-Mis18 PF03226.14 KKK12498.1 - 0.029 14.6 1.6 0.078 13.2 1.6 1.7 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zinc_ribbon_10 PF10058.9 KKK12498.1 - 0.061 13.1 1.5 1.2 8.9 0.0 2.3 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein zf_ZIC PF18366.1 KKK12499.1 - 0.0003 20.8 0.0 0.0008 19.5 0.0 1.7 1 0 0 1 1 1 1 Zic proteins zinc finger domain RFX_DNA_binding PF02257.15 KKK12499.1 - 0.026 15.1 0.0 0.051 14.2 0.0 1.4 1 0 0 1 1 1 0 RFX DNA-binding domain Arm PF00514.23 KKK12499.1 - 0.21 11.7 1.1 2.6 8.2 0.1 3.1 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat Meiotic_rec114 PF03525.14 KKK12500.1 - 3e-05 23.1 10.5 4.2e-05 22.7 4.1 2.5 2 2 0 2 2 2 2 Meiotic recombination protein rec114 Zn_clus PF00172.18 KKK12501.1 - 5.5e-10 39.2 8.7 9.1e-10 38.5 8.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.18 KKK12510.1 - 1.3e-10 41.2 9.8 2.4e-10 40.4 9.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KKK12510.1 - 0.12 11.4 0.0 0.2 10.6 0.0 1.4 1 0 0 1 1 1 0 Fungal specific transcription factor domain FMN_dh PF01070.18 KKK12511.1 - 5.8e-104 347.9 0.7 5.8e-75 252.5 0.4 2.5 1 1 1 2 2 2 2 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 KKK12511.1 - 1e-22 80.0 0.0 2.2e-22 79.0 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 KKK12511.1 - 0.00018 20.8 0.0 0.00034 19.9 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 KKK12511.1 - 0.00055 19.0 0.1 0.0017 17.5 0.1 1.7 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 KKK12511.1 - 0.015 14.8 0.1 0.027 13.9 0.1 1.4 1 0 0 1 1 1 0 Nitronate monooxygenase His_biosynth PF00977.21 KKK12511.1 - 0.079 12.4 0.3 1 8.7 0.1 2.1 1 1 1 2 2 2 0 Histidine biosynthesis protein ThiG PF05690.14 KKK12511.1 - 0.26 10.6 0.6 15 4.8 0.0 2.3 1 1 0 2 2 2 0 Thiazole biosynthesis protein ThiG Glyco_hydro_3 PF00933.21 KKK12513.1 - 7.8e-43 147.1 0.0 1.1e-42 146.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 KKK12513.1 - 5.4e-41 140.8 0.0 1.9e-40 139.0 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain DUF572 PF04502.13 KKK12513.1 - 3.3e-27 96.0 0.0 4.7e-27 95.5 0.0 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF572) Fn3-like PF14310.6 KKK12513.1 - 1.9e-17 63.1 0.9 3.6e-17 62.2 0.9 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Cation_ATPase_C PF00689.21 KKK12549.1 - 1.2e-45 155.5 9.7 1.2e-45 155.5 9.7 2.8 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 KKK12549.1 - 1.5e-35 122.3 0.6 1.5e-35 122.3 0.6 2.3 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase PF13246.6 KKK12549.1 - 2.2e-22 78.9 0.0 4.9e-22 77.8 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KKK12549.1 - 3.2e-19 70.0 0.0 8.9e-19 68.6 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KKK12549.1 - 1.6e-08 34.1 0.3 1.2e-07 31.3 0.0 2.5 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KKK12549.1 - 0.0016 18.2 1.3 0.0037 17.0 0.7 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase RskA PF10099.9 KKK12549.1 - 0.0027 18.0 3.5 3.7 7.8 0.0 4.0 3 1 0 3 3 3 2 Anti-sigma-K factor rskA LptF_LptG PF03739.14 KKK12549.1 - 0.013 14.4 4.4 0.033 13.0 4.4 1.7 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG DUF4870 PF09685.10 KKK12549.1 - 0.11 12.6 0.1 0.11 12.6 0.1 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4870) FAD_binding_6 PF00970.24 KKK12561.1 - 1e-32 112.4 0.0 1.5e-32 111.9 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 KKK12561.1 - 8.2e-29 100.4 0.0 1.3e-28 99.8 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 KKK12561.1 - 1.5e-06 28.4 0.0 0.0002 21.5 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 KKK12561.1 - 0.012 15.8 0.0 0.022 14.9 0.0 1.4 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain DUF4176 PF13780.6 KKK12561.1 - 0.1 12.7 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4176) SMC_N PF02463.19 KKK12562.1 - 6.5e-73 244.8 0.0 1.1e-72 244.0 0.0 1.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KKK12562.1 - 6e-32 110.4 0.1 3.2e-31 108.1 0.0 2.4 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.6 KKK12562.1 - 4.3e-19 69.8 0.2 4.3e-19 69.8 0.2 7.4 1 1 3 5 5 2 1 AAA domain AAA_21 PF13304.6 KKK12562.1 - 3.7e-16 59.8 13.5 2.2e-10 40.8 0.0 4.1 4 1 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 KKK12562.1 - 2.3e-13 50.6 55.5 2.8e-07 30.6 24.6 4.7 2 2 1 3 3 2 2 AAA ATPase domain APG6_N PF17675.1 KKK12562.1 - 0.00073 20.1 9.6 0.00073 20.1 9.6 8.5 3 2 5 8 8 8 4 Apg6 coiled-coil region Spc7 PF08317.11 KKK12562.1 - 0.0045 15.9 9.6 0.0045 15.9 9.6 7.5 2 2 5 7 7 7 2 Spc7 kinetochore protein AAA_29 PF13555.6 KKK12562.1 - 0.0051 16.5 0.0 0.012 15.3 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain FliD_N PF02465.18 KKK12562.1 - 0.026 15.2 1.3 0.026 15.2 1.3 8.4 5 3 3 8 8 8 0 Flagellar hook-associated protein 2 N-terminus DUF1192 PF06698.11 KKK12562.1 - 0.079 13.0 0.1 0.079 13.0 0.1 5.8 7 0 0 7 7 6 0 Protein of unknown function (DUF1192) FtsK_SpoIIIE PF01580.18 KKK12562.1 - 0.14 11.5 0.0 0.14 11.5 0.0 3.9 3 1 1 4 4 4 0 FtsK/SpoIIIE family ABC_tran PF00005.27 KKK12562.1 - 0.51 10.8 0.0 0.51 10.8 0.0 6.1 3 2 0 3 3 1 0 ABC transporter DUF87 PF01935.17 KKK12562.1 - 2.9 7.9 0.0 2.9 7.9 0.0 6.7 3 2 1 6 6 5 0 Helicase HerA, central domain DUF3605 PF12239.8 KKK12563.1 - 1.7e-57 194.1 0.0 2e-57 193.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) KH_1 PF00013.29 KKK12564.1 - 4.5e-30 103.3 2.1 1.9e-06 27.6 0.1 7.0 7 0 0 7 7 7 5 KH domain RIO1 PF01163.22 KKK12565.1 - 5.5e-74 247.9 0.1 5.5e-74 247.9 0.1 1.8 2 0 0 2 2 2 1 RIO1 family APH PF01636.23 KKK12565.1 - 0.061 13.2 0.0 12 5.7 0.0 2.5 1 1 1 2 2 2 0 Phosphotransferase enzyme family APG17 PF04108.12 KKK12566.1 - 1.8e-137 458.7 0.1 2.1e-137 458.4 0.1 1.0 1 0 0 1 1 1 1 Autophagy protein Apg17 RasGAP_C PF03836.15 KKK12566.1 - 0.23 11.6 3.5 18 5.5 0.1 3.8 3 1 1 4 4 4 0 RasGAP C-terminus Hydrolase PF00702.26 KKK12567.1 - 5.6e-09 36.6 0.0 2.2e-08 34.7 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KKK12567.1 - 2.3e-08 34.4 0.0 2.9e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KKK12567.1 - 0.012 15.7 0.0 0.021 14.9 0.0 1.4 1 0 0 1 1 1 0 HAD-hyrolase-like DUF4437 PF14499.6 KKK12567.1 - 0.016 14.4 0.0 0.024 13.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4437) 5_nucleotid PF05761.14 KKK12567.1 - 0.032 13.1 0.1 0.17 10.8 0.0 1.9 1 1 1 2 2 2 0 5' nucleotidase family HAD PF12710.7 KKK12567.1 - 0.12 12.7 0.0 0.16 12.4 0.0 1.2 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Solute_trans_a PF03619.16 KKK12568.1 - 1.3e-91 306.8 3.1 1.7e-91 306.5 3.1 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha WD40 PF00400.32 KKK12571.1 - 4.7e-50 166.5 17.9 7.2e-08 33.0 0.0 8.5 8 0 0 8 8 8 6 WD domain, G-beta repeat F-box-like PF12937.7 KKK12571.1 - 2.3e-14 53.0 0.7 5.4e-14 51.8 0.7 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KKK12571.1 - 9.1e-12 44.5 1.4 5.7e-11 42.0 0.3 2.4 1 1 1 2 2 2 1 F-box domain Nup160 PF11715.8 KKK12571.1 - 2.1e-09 36.6 8.3 0.022 13.4 0.7 5.8 4 1 2 6 6 6 4 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 KKK12571.1 - 8.4e-07 29.2 0.0 0.02 15.2 0.0 4.8 3 1 3 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain F-box_4 PF15966.5 KKK12571.1 - 0.00082 19.2 0.6 0.0036 17.2 0.0 2.3 2 1 1 3 3 3 1 F-box PRANC PF09372.10 KKK12571.1 - 0.13 12.6 0.0 0.24 11.8 0.0 1.4 1 0 0 1 1 1 0 PRANC domain Peptidase_A22B PF04258.13 KKK12573.1 - 1.6e-61 208.4 0.5 4.9e-61 206.8 0.5 1.7 1 1 0 1 1 1 1 Signal peptide peptidase SPP PF06550.11 KKK12573.1 - 1.6e-05 24.6 0.8 1.6e-05 24.6 0.8 2.1 2 0 0 2 2 2 1 Signal-peptide peptidase, presenilin aspartyl protease FUSC_2 PF13515.6 KKK12573.1 - 0.051 13.7 0.2 0.051 13.7 0.2 2.4 2 0 0 2 2 2 0 Fusaric acid resistance protein-like FAM176 PF14851.6 KKK12573.1 - 1 9.0 0.0 1 9.0 0.0 3.4 3 1 0 3 3 3 0 FAM176 family RNase_PH PF01138.21 KKK12574.1 - 1.9e-16 60.7 2.6 1.6e-14 54.6 2.6 2.4 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KKK12574.1 - 0.1 12.6 0.0 0.41 10.7 0.0 2.0 1 1 0 1 1 1 0 3' exoribonuclease family, domain 2 GDI PF00996.18 KKK12575.1 - 3e-25 88.6 0.0 1.3e-24 86.5 0.0 1.8 1 1 0 1 1 1 1 GDP dissociation inhibitor Pro_isomerase PF00160.21 KKK12576.1 - 7.2e-54 182.3 0.1 8.2e-54 182.1 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF604 PF04646.12 KKK12577.1 - 2.8e-08 33.5 0.0 4.5e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF604 Fringe PF02434.16 KKK12577.1 - 1.7e-05 24.4 0.0 3.7e-05 23.3 0.0 1.4 1 1 0 1 1 1 1 Fringe-like DUF3844 PF12955.7 KKK12628.1 - 1.2e-35 121.8 2.9 2e-35 121.1 2.9 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3844) Ceramidase_alk PF04734.13 KKK12628.1 - 0.026 13.2 2.1 0.037 12.7 2.1 1.1 1 0 0 1 1 1 0 Neutral/alkaline non-lysosomal ceramidase, N-terminal Pro_isomerase PF00160.21 KKK12629.1 - 1.9e-50 171.2 0.5 2.3e-50 170.9 0.5 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD tRNA-synt_2c PF01411.19 KKK12631.1 - 1.7e-217 723.3 0.1 2.6e-217 722.7 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 KKK12631.1 - 5.1e-17 61.7 0.4 1.2e-16 60.5 0.4 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 KKK12631.1 - 3.2e-13 50.3 2.9 6.3e-13 49.3 0.2 2.6 2 0 0 2 2 2 1 DHHA1 domain SH3BGR PF04908.15 KKK12631.1 - 0.12 12.5 0.1 0.36 11.0 0.1 1.8 1 0 0 1 1 1 0 SH3-binding, glutamic acid-rich protein CPSF_A PF03178.15 KKK12632.1 - 4.4e-111 371.3 0.0 1.7e-110 369.3 0.0 2.0 2 0 0 2 2 2 1 CPSF A subunit region Thioredoxin_4 PF13462.6 KKK12633.1 - 7.1e-07 29.5 0.0 9.7e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Phage_TAC_6 PF09550.10 KKK12633.1 - 0.043 14.2 0.1 0.13 12.8 0.1 1.7 2 0 0 2 2 2 0 Phage tail assembly chaperone protein, TAC DSBA PF01323.20 KKK12633.1 - 0.094 12.5 1.6 3.1 7.5 0.3 2.3 1 1 0 2 2 2 0 DSBA-like thioredoxin domain TrkA_N PF02254.18 KKK12634.1 - 0.25 11.6 0.0 0.44 10.8 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain zf-RING_2 PF13639.6 KKK12635.1 - 1.9e-13 50.5 2.9 3e-13 49.9 2.9 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KKK12635.1 - 1.1e-10 41.2 2.3 1.7e-10 40.6 2.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KKK12635.1 - 9.5e-09 34.9 1.3 1.7e-08 34.1 1.3 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 KKK12635.1 - 1.6e-08 34.3 0.9 2.5e-08 33.6 0.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KKK12635.1 - 2.3e-07 31.0 6.9 1.4e-06 28.5 6.9 2.1 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KKK12635.1 - 8e-07 28.9 0.7 1.2e-06 28.3 0.7 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KKK12635.1 - 7.8e-06 25.8 0.3 4.2e-05 23.5 0.0 2.2 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KKK12635.1 - 0.00023 20.9 0.5 0.00038 20.2 0.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KKK12635.1 - 0.00026 21.0 1.4 0.0008 19.4 1.4 1.8 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 KKK12635.1 - 0.0016 18.0 1.7 0.0028 17.2 1.7 1.3 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3HC4_4 PF15227.6 KKK12635.1 - 0.0016 18.6 1.7 0.0042 17.2 1.7 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 KKK12635.1 - 0.0065 16.3 2.9 0.015 15.1 2.9 1.6 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 KKK12635.1 - 0.0091 15.8 3.0 0.015 15.0 3.0 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain PHD PF00628.29 KKK12635.1 - 0.0092 15.9 2.3 0.016 15.1 2.3 1.4 1 0 0 1 1 1 1 PHD-finger RINGv PF12906.7 KKK12635.1 - 0.039 14.1 1.2 0.083 13.0 1.2 1.6 1 1 0 1 1 1 0 RING-variant domain DUF4617 PF15395.6 KKK12635.1 - 0.16 10.2 0.3 0.23 9.7 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4617) Prok-RING_1 PF14446.6 KKK12635.1 - 0.22 11.5 4.0 0.18 11.7 0.9 2.0 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-RING_10 PF16685.5 KKK12635.1 - 0.22 11.7 1.0 0.39 10.9 1.0 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 FANCL_C PF11793.8 KKK12635.1 - 0.24 11.6 3.0 0.72 10.1 3.0 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING-like PF08746.11 KKK12635.1 - 0.31 11.4 2.1 0.57 10.5 2.1 1.5 1 0 0 1 1 1 0 RING-like domain zf-C3H2C3 PF17122.5 KKK12635.1 - 0.38 10.8 3.6 0.38 10.8 1.8 1.9 2 1 0 2 2 1 0 Zinc-finger Fungal_trans PF04082.18 KKK12636.1 - 1.3e-07 31.0 0.2 2.7e-07 29.9 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK12636.1 - 5.6e-07 29.6 8.1 1.1e-06 28.7 8.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HSP70 PF00012.20 KKK12638.1 - 4.1e-225 748.5 8.1 4.1e-225 748.5 8.1 2.0 2 0 0 2 2 2 1 Hsp70 protein RRF PF01765.19 KKK12638.1 - 8.4e-44 149.4 2.4 8.4e-44 149.4 2.4 2.8 4 1 1 5 5 5 1 Ribosome recycling factor MreB_Mbl PF06723.13 KKK12638.1 - 3.5e-16 58.9 0.1 3.1e-15 55.8 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 KKK12638.1 - 0.00077 19.2 0.0 0.002 17.9 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain HEPPP_synt_1 PF07307.11 KKK12638.1 - 0.096 12.3 0.2 8 6.0 0.0 2.5 2 0 0 2 2 2 0 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 ApoLp-III PF07464.11 KKK12638.1 - 5.4 7.1 8.2 6.6 6.8 1.2 2.9 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) CKS PF01111.19 KKK12639.1 - 8.1e-35 118.9 0.5 1.2e-34 118.4 0.5 1.2 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit GTP_EFTU PF00009.27 KKK12640.1 - 1.1e-46 158.8 0.0 1.6e-46 158.3 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFTUD2 PF16004.5 KKK12640.1 - 1.6e-38 132.0 10.3 3e-38 131.1 10.3 1.5 1 0 0 1 1 1 1 116 kDa U5 small nuclear ribonucleoprotein component N-terminus EFG_IV PF03764.18 KKK12640.1 - 5.5e-24 84.3 0.0 1.8e-23 82.6 0.0 1.9 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 KKK12640.1 - 4.5e-20 71.5 0.0 1.2e-19 70.2 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KKK12640.1 - 1.9e-11 44.2 0.0 4.8e-11 42.9 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 KKK12640.1 - 2.6e-07 30.6 0.1 7.4e-07 29.2 0.0 1.8 2 0 0 2 2 2 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 KKK12640.1 - 2.8e-05 24.2 0.1 5.2e-05 23.3 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 KKK12640.1 - 0.063 12.7 0.1 0.43 10.0 0.1 2.2 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Septin PF00735.18 KKK12640.1 - 0.091 12.0 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 Septin DUF5505 PF17610.2 KKK12640.1 - 0.12 12.3 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5505) FeS_assembly_P PF01883.19 KKK12641.1 - 7.6e-09 35.6 0.0 2.8e-08 33.8 0.0 2.0 1 1 0 1 1 1 1 Iron-sulfur cluster assembly protein Pheromone PF08015.11 KKK12641.1 - 0.14 13.2 2.5 5.6 8.1 0.0 2.7 3 0 0 3 3 3 0 Fungal mating-type pheromone Atg14 PF10186.9 KKK12642.1 - 2.9e-75 253.3 0.9 3.9e-75 252.9 0.9 1.1 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 LemA PF04011.12 KKK12643.1 - 0.026 14.4 0.2 0.032 14.1 0.2 1.3 1 0 0 1 1 1 0 LemA family Barstar PF01337.18 KKK12643.1 - 0.13 12.4 0.3 1.9 8.6 0.0 2.2 2 0 0 2 2 2 0 Barstar (barnase inhibitor) LMBR1 PF04791.16 KKK12644.1 - 9.8e-15 54.4 17.2 3.1e-14 52.8 3.0 2.4 1 1 1 2 2 2 2 LMBR1-like membrane protein DUF2040 PF09745.9 KKK12644.1 - 0.84 9.7 4.6 0.15 12.1 0.8 1.6 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 55 (DUF2040) Thiolase_N PF00108.23 KKK12645.1 - 4.5e-93 311.4 1.5 5.8e-93 311.0 0.2 1.7 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KKK12645.1 - 8.4e-45 151.4 3.3 1.3e-44 150.8 2.6 1.7 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KKK12645.1 - 3.3e-05 23.6 4.5 4.2e-05 23.3 2.9 2.0 2 1 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 KKK12645.1 - 0.028 14.3 3.3 0.39 10.6 0.1 3.0 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Zip PF02535.22 KKK12646.1 - 1.3e-33 116.6 0.0 2.1e-33 116.0 0.0 1.3 1 1 0 1 1 1 1 ZIP Zinc transporter COS PF18568.1 KKK12646.1 - 0.081 12.9 0.1 0.2 11.6 0.1 1.6 1 0 0 1 1 1 0 TRIM C-terminal subgroup One Signature domain Ras PF00071.22 KKK12667.1 - 2.4e-52 176.8 0.0 2.7e-52 176.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KKK12667.1 - 7e-19 68.2 0.0 9.4e-19 67.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKK12667.1 - 4.2e-06 26.3 0.0 5.6e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Arginase PF00491.21 KKK12668.1 - 4e-75 252.9 0.0 5.1e-75 252.6 0.0 1.0 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.7 KKK12668.1 - 0.0022 18.3 0.0 0.0034 17.6 0.0 1.2 1 0 0 1 1 1 1 UPF0489 domain DUF1349 PF07081.11 KKK12669.1 - 5.3e-29 101.2 0.0 6.6e-29 100.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1349) MFS_1 PF07690.16 KKK12670.1 - 4.6e-23 81.7 38.8 1.4e-13 50.5 16.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KKK12670.1 - 2.7e-06 26.1 21.3 4.5e-06 25.4 21.3 1.3 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Pox_A14 PF05767.12 KKK12670.1 - 0.045 13.9 0.2 0.045 13.9 0.2 2.5 3 0 0 3 3 3 0 Poxvirus virion envelope protein A14 DUF5357 PF17310.2 KKK12670.1 - 0.058 11.9 1.3 0.13 10.8 1.3 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5357) CAP59_mtransfer PF11735.8 KKK12672.1 - 7.9e-69 232.0 0.0 1e-68 231.6 0.0 1.2 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 Aa_trans PF01490.18 KKK12674.1 - 2.5e-33 115.4 35.3 1.1e-30 106.7 20.5 2.0 1 1 1 2 2 2 2 Transmembrane amino acid transporter protein Glyco_hydro_18 PF00704.28 KKK12675.1 - 8.2e-38 130.9 0.0 1e-37 130.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Pectate_lyase_3 PF12708.7 KKK12676.1 - 6.3e-63 212.5 17.7 3e-54 184.1 7.1 4.6 5 1 0 6 6 6 2 Pectate lyase superfamily protein SLT PF01464.20 KKK12676.1 - 0.0026 17.4 0.1 0.014 15.1 0.1 2.1 2 0 0 2 2 2 1 Transglycosylase SLT domain End_N_terminal PF12218.8 KKK12676.1 - 0.56 10.0 4.1 0.26 11.0 0.1 2.6 3 0 0 3 3 3 0 N terminal extension of bacteriophage endosialidase Sugar_tr PF00083.24 KKK12677.1 - 1.7e-99 333.8 20.8 1.9e-99 333.6 20.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKK12677.1 - 9.1e-34 116.9 44.1 6.4e-29 101.0 24.4 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily MARVEL PF01284.23 KKK12677.1 - 2.9 7.9 15.2 0.11 12.6 1.4 2.8 2 0 0 2 2 2 0 Membrane-associating domain Glyco_hydro_2_N PF02837.18 KKK12678.1 - 1.4e-10 41.3 0.0 2.6e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Zn_clus PF00172.18 KKK12678.1 - 3e-08 33.6 8.0 8.9e-08 32.1 8.0 1.9 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_2_C PF02836.17 KKK12678.1 - 5.4e-08 32.3 0.1 6.3e-07 28.8 0.1 2.2 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Fungal_trans PF04082.18 KKK12678.1 - 1.6e-06 27.3 1.1 3.6e-06 26.2 1.1 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_2 PF00703.21 KKK12678.1 - 2.2e-05 25.1 0.1 0.00011 22.8 0.1 2.2 1 1 0 1 1 1 1 Glycosyl hydrolases family 2 tify PF06200.14 KKK12678.1 - 0.22 10.9 0.8 0.46 9.9 0.8 1.6 1 0 0 1 1 1 0 tify domain Ctr PF04145.15 KKK12679.1 - 7e-37 127.3 3.7 1.2e-36 126.6 3.7 1.4 1 0 0 1 1 1 1 Ctr copper transporter family Aegerolysin PF06355.13 KKK12680.1 - 1.6e-42 144.7 0.0 1.9e-42 144.5 0.0 1.0 1 0 0 1 1 1 1 Aegerolysin Ferric_reduct PF01794.19 KKK12681.1 - 7.3e-22 77.8 13.6 7.3e-22 77.8 13.6 2.1 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KKK12681.1 - 7.8e-16 58.6 0.0 6.3e-15 55.6 0.0 2.0 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KKK12681.1 - 1.5e-10 41.2 0.0 2.7e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 KKK12681.1 - 0.00019 22.0 0.0 0.00057 20.5 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Dickkopf_N PF04706.12 KKK12682.1 - 0.18 12.3 25.0 0.5 10.9 12.6 2.6 1 1 1 2 2 2 0 Dickkopf N-terminal cysteine-rich region Aldedh PF00171.22 KKK12683.1 - 8.2e-140 466.4 0.0 9.6e-140 466.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Glyco_hydro_2_C PF02836.17 KKK12684.1 - 1.2e-104 349.7 0.0 1.7e-104 349.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Bgal_small_N PF02929.17 KKK12684.1 - 6.5e-67 225.7 0.0 1.2e-66 224.8 0.0 1.4 1 0 0 1 1 1 1 Beta galactosidase small chain Glyco_hydro_2_N PF02837.18 KKK12684.1 - 1.3e-45 155.3 0.3 3.8e-45 153.8 0.2 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain DUF4981 PF16353.5 KKK12684.1 - 4.2e-17 62.4 0.1 6.1e-16 58.7 0.0 2.6 2 0 0 2 2 2 1 Domain of unknown function(DUF4981) Glyco_hydro_2 PF00703.21 KKK12684.1 - 3.1e-16 60.0 0.6 6.3e-16 59.0 0.6 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 MFS_1 PF07690.16 KKK12685.1 - 1.6e-28 99.6 24.6 2.2e-28 99.2 24.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Glyco_hydro_88 PF07470.13 KKK12686.1 - 3.4e-79 266.4 4.5 6.3e-63 212.9 0.3 2.1 1 1 1 2 2 2 2 Glycosyl Hydrolase Family 88 Amidohydro_1 PF01979.20 KKK12686.1 - 1.5e-71 241.5 0.3 5.3e-71 239.7 0.1 1.8 2 0 0 2 2 2 1 Amidohydrolase family Amidohydro_3 PF07969.11 KKK12686.1 - 3.7e-20 72.8 2.7 1.2e-14 54.7 0.2 3.0 3 0 0 3 3 3 2 Amidohydrolase family A_deaminase PF00962.22 KKK12686.1 - 0.016 14.6 0.0 0.04 13.2 0.0 1.6 1 1 0 1 1 1 0 Adenosine/AMP deaminase Ribo_biogen_C PF04034.13 KKK12711.1 - 4.5e-33 113.7 0.2 6.4e-33 113.2 0.2 1.2 1 0 0 1 1 1 1 Ribosome biogenesis protein, C-terminal ALAD PF00490.21 KKK12727.1 - 1.4e-122 408.8 0.0 1.7e-122 408.6 0.0 1.1 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase Mac_assoc PF16628.5 KKK12728.1 - 1.6e-86 289.3 5.9 1.6e-86 289.3 5.9 2.6 2 1 0 2 2 2 1 Unstructured region on maltose acetyltransferase Mac PF12464.8 KKK12728.1 - 5.6e-13 48.9 0.1 2.4e-12 46.9 0.0 2.1 2 0 0 2 2 2 1 Maltose acetyltransferase Hexapep PF00132.24 KKK12728.1 - 6.8e-10 38.3 1.4 0.00062 19.4 0.1 3.5 3 0 0 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Zn_clus PF00172.18 KKK12728.1 - 1.1e-09 38.2 8.4 2.2e-09 37.3 8.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Hexapep_2 PF14602.6 KKK12728.1 - 8.8e-09 35.0 2.3 1e-06 28.4 0.1 3.7 4 0 0 4 4 4 1 Hexapeptide repeat of succinyl-transferase DAGK_cat PF00781.24 KKK12729.1 - 4.4e-13 48.9 0.0 7.7e-13 48.2 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain zf-C2H2 PF00096.26 KKK12747.1 - 0.00013 22.2 11.2 0.063 13.8 1.4 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KKK12747.1 - 0.0092 16.4 1.9 3.1 8.4 0.1 2.8 2 0 0 2 2 2 2 Zinc-finger double domain OAD_gamma PF04277.13 KKK12752.1 - 0.46 11.1 2.7 0.46 11.1 2.7 1.1 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain SKG6 PF08693.10 KKK12752.1 - 0.96 8.9 4.8 1 8.9 4.8 1.1 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DNA_pol_A_exo1 PF01612.20 KKK12793.1 - 2e-21 76.5 0.0 2.9e-21 76.0 0.0 1.1 1 0 0 1 1 1 1 3'-5' exonuclease LSM PF01423.22 KKK12794.1 - 8.5e-15 54.2 0.1 9.8e-15 54.0 0.1 1.1 1 0 0 1 1 1 1 LSM domain Lactamase_B PF00753.27 KKK12796.1 - 0.019 15.0 0.2 0.039 14.0 0.2 1.4 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily PX PF00787.24 KKK12798.1 - 9.1e-14 51.4 0.0 2.4e-13 50.1 0.0 1.7 2 0 0 2 2 2 1 PX domain DGF-1_C PF11040.8 KKK12798.1 - 0.059 13.4 0.9 0.14 12.2 0.1 2.1 2 0 0 2 2 2 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus UPF0242 PF06785.11 KKK12798.1 - 8 6.5 8.9 27 4.8 9.2 1.7 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus SIP1 PF04938.12 KKK12799.1 - 3.7e-10 39.9 0.0 5.5e-08 32.8 0.0 2.7 2 1 0 2 2 2 2 Survival motor neuron (SMN) interacting protein 1 (SIP1) Pkinase PF00069.25 KKK12800.1 - 6.1e-13 48.7 0.0 1e-12 48.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KKK12800.1 - 0.0038 17.2 0.0 0.0044 17.0 0.0 1.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KKK12800.1 - 0.0058 16.0 0.0 0.009 15.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KKK12800.1 - 0.014 14.8 0.0 0.02 14.3 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 KKK12800.1 - 0.016 14.5 0.1 0.039 13.2 0.1 1.6 1 1 0 1 1 1 0 Protein tyrosine kinase RIO1 PF01163.22 KKK12800.1 - 0.14 11.7 0.0 0.23 11.0 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Ku_PK_bind PF08785.11 KKK12801.1 - 1.3e-35 122.1 0.0 3e-35 121.0 0.0 1.7 1 0 0 1 1 1 1 Ku C terminal domain like Ku PF02735.16 KKK12801.1 - 1.9e-32 112.6 0.0 3e-32 112.0 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 KKK12801.1 - 2e-09 37.5 0.0 4.1e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain VWA PF00092.28 KKK12801.1 - 0.0053 17.0 0.0 0.014 15.6 0.0 1.7 1 1 0 1 1 1 1 von Willebrand factor type A domain tRNA-synt_2 PF00152.20 KKK12802.1 - 3.2e-70 236.7 0.1 4.3e-70 236.3 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) Hydrolase_6 PF13344.6 KKK12802.1 - 6.1e-24 84.1 0.0 1.7e-23 82.6 0.0 1.8 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KKK12802.1 - 1.6e-11 44.1 0.0 7.3e-10 38.8 0.0 2.6 2 0 0 2 2 2 1 HAD-hyrolase-like tRNA_anti-codon PF01336.25 KKK12802.1 - 2.6e-05 24.1 0.1 5e-05 23.2 0.1 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Hydrolase PF00702.26 KKK12802.1 - 0.00077 19.8 1.4 0.48 10.7 0.0 3.5 3 1 0 3 3 3 2 haloacid dehalogenase-like hydrolase eIF3_subunit PF08597.10 KKK12802.1 - 0.02 14.8 2.1 0.036 14.0 2.1 1.3 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit F-box-like PF12937.7 KKK12803.1 - 1.8e-07 30.9 0.1 4e-07 29.8 0.1 1.7 1 0 0 1 1 1 1 F-box-like POTRA_1 PF08478.10 KKK12803.1 - 0.014 15.7 0.0 0.031 14.6 0.0 1.6 1 0 0 1 1 1 0 POTRA domain, FtsQ-type F-box PF00646.33 KKK12803.1 - 0.071 13.0 0.0 0.071 13.0 0.0 3.6 5 0 0 5 5 5 0 F-box domain Sugar_tr PF00083.24 KKK12804.1 - 3.9e-71 240.3 21.0 5.4e-71 239.8 21.0 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKK12804.1 - 5.5e-12 45.3 39.6 5.5e-12 45.3 39.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KKK12804.1 - 0.0067 15.3 3.3 0.0067 15.3 3.3 2.2 2 0 0 2 2 2 1 MFS_1 like family Trp_oprn_chp PF09534.10 KKK12804.1 - 0.46 10.3 13.5 0.12 12.2 6.8 2.8 3 0 0 3 3 3 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) KH_1 PF00013.29 KKK12805.1 - 9.3e-42 140.7 6.3 1.6e-16 59.9 0.1 3.3 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 KKK12805.1 - 4.6e-10 39.2 8.0 0.0018 18.1 0.1 3.4 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 KKK12805.1 - 2.1e-07 30.7 7.6 0.045 13.6 0.2 3.3 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 KKK12805.1 - 0.0003 20.8 6.0 0.43 10.7 0.1 3.5 3 0 0 3 3 3 2 NusA-like KH domain MOEP19 PF16005.5 KKK12805.1 - 0.039 14.0 0.0 30 4.7 0.0 3.1 3 0 0 3 3 3 0 KH-like RNA-binding domain ECR1_N PF14382.6 KKK12805.1 - 0.061 13.1 0.0 0.17 11.7 0.0 1.7 1 0 0 1 1 1 0 Exosome complex exonuclease RRP4 N-terminal region GARS_C PF02843.16 KKK12805.1 - 0.063 13.6 0.1 0.35 11.2 0.0 2.3 3 0 0 3 3 3 0 Phosphoribosylglycinamide synthetase, C domain ECF-ribofla_trS PF07155.12 KKK12805.1 - 0.065 13.2 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 ECF-type riboflavin transporter, S component Adaptin_N PF01602.20 KKK12806.1 - 1.6e-113 380.0 0.1 2.1e-113 379.6 0.1 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.10 KKK12806.1 - 5.5e-59 198.6 4.6 1.3e-58 197.4 4.6 1.7 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain Coatomer_g_Cpla PF16381.5 KKK12806.1 - 1.2e-34 118.9 0.5 9.3e-34 116.0 0.1 2.7 2 0 0 2 2 2 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT_2 PF13646.6 KKK12806.1 - 5e-18 65.3 0.8 3.7e-11 43.2 0.0 5.6 5 1 1 6 6 6 3 HEAT repeats Cnd1 PF12717.7 KKK12806.1 - 5.8e-09 36.2 8.0 0.0018 18.4 0.2 5.0 4 1 2 6 6 6 2 non-SMC mitotic condensation complex subunit 1 HEAT_PBS PF03130.16 KKK12806.1 - 0.0033 17.9 0.9 14 6.7 0.0 4.9 4 0 0 4 4 4 1 PBS lyase HEAT-like repeat UNC45-central PF11701.8 KKK12806.1 - 0.1 12.6 1.8 31 4.5 0.1 3.9 3 1 0 3 3 3 0 Myosin-binding striated muscle assembly central DUF5010 PF16402.5 KKK12806.1 - 0.13 11.1 0.0 2.3 6.9 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5010) HEAT PF02985.22 KKK12806.1 - 0.31 11.4 7.5 61 4.3 0.2 5.8 6 0 0 6 6 6 0 HEAT repeat dCMP_cyt_deam_1 PF00383.23 KKK12810.1 - 1.6e-14 53.6 0.3 2e-14 53.3 0.3 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.12 KKK12810.1 - 2.4e-08 34.3 0.6 3e-08 33.9 0.6 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Peptidase_M42 PF05343.14 KKK12810.1 - 0.027 13.5 0.0 0.029 13.4 0.0 1.1 1 0 0 1 1 1 0 M42 glutamyl aminopeptidase LmjF365940-deam PF14421.6 KKK12810.1 - 0.092 12.3 1.7 0.28 10.8 0.1 2.0 1 1 1 2 2 2 0 A distinct subfamily of CDD/CDA-like deaminases Mito_carr PF00153.27 KKK12811.1 - 1.2e-66 220.6 0.2 4.7e-22 77.7 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KKK12811.1 - 0.057 12.6 0.1 7.9 5.5 0.0 3.1 3 1 0 3 3 3 0 Gammaproteobacterial serine protease Cgr1 PF03879.14 KKK12812.1 - 1.6e-33 115.3 29.2 1.8e-33 115.2 29.2 1.0 1 0 0 1 1 1 1 Cgr1 family RRT14 PF17075.5 KKK12812.1 - 0.26 11.4 15.8 0.35 11.0 15.8 1.1 1 0 0 1 1 1 0 Regular of rDNA transcription protein 14 COX16 PF14138.6 KKK12812.1 - 6.6 7.3 11.3 12 6.5 11.3 1.5 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein COX16 GAS PF13851.6 KKK12813.1 - 0.00029 20.3 1.2 0.00045 19.6 1.2 1.2 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding AAA_13 PF13166.6 KKK12813.1 - 0.001 17.8 0.6 0.0013 17.4 0.6 1.0 1 0 0 1 1 1 1 AAA domain Spc7 PF08317.11 KKK12813.1 - 0.0012 17.8 0.9 0.0018 17.2 0.9 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF3287 PF11690.8 KKK12813.1 - 0.014 15.1 0.2 0.027 14.2 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3287) Phlebovirus_NSM PF07246.11 KKK12813.1 - 0.061 12.7 0.7 0.1 11.9 0.7 1.3 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M OmpH PF03938.14 KKK12813.1 - 0.12 12.7 1.4 0.21 11.9 1.4 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) T2SSF PF00482.23 KKK12813.1 - 0.13 12.3 0.3 0.26 11.2 0.3 1.5 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F TEX13 PF15186.6 KKK12813.1 - 0.14 11.8 3.7 0.2 11.3 2.8 1.6 1 1 0 1 1 1 0 Testis-expressed sequence 13 protein family CtIP_N PF10482.9 KKK12813.1 - 0.17 12.0 2.3 0.31 11.1 2.3 1.3 1 0 0 1 1 1 0 Tumour-suppressor protein CtIP N-terminal domain DUF1664 PF07889.12 KKK12813.1 - 0.19 11.8 0.4 2.3 8.3 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) EMP24_GP25L PF01105.24 KKK12813.1 - 0.23 11.4 1.1 0.42 10.5 1.1 1.4 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD DUF1488 PF07369.11 KKK12813.1 - 0.26 11.3 1.1 5.9 7.0 1.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1488) DUF16 PF01519.16 KKK12813.1 - 0.41 11.1 5.3 0.53 10.8 2.2 2.1 2 0 0 2 2 2 0 Protein of unknown function DUF16 DUF2550 PF10739.9 KKK12814.1 - 0.014 15.4 0.0 0.029 14.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2550) SNAD3 PF18749.1 KKK12814.1 - 0.092 11.9 0.0 0.11 11.6 0.0 1.1 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 3 Methyltransf_2 PF00891.18 KKK12815.1 - 3.4e-25 88.6 0.0 2.1e-24 86.0 0.0 2.0 1 1 0 1 1 1 1 O-methyltransferase domain Dimerisation2 PF16864.5 KKK12815.1 - 0.0062 16.5 0.0 0.021 14.8 0.0 1.9 1 0 0 1 1 1 1 Dimerisation domain Dimerisation PF08100.11 KKK12815.1 - 0.028 14.4 0.1 0.13 12.4 0.1 2.1 1 1 0 1 1 1 0 Dimerisation domain Methyltransf_33 PF10017.9 KKK12815.1 - 0.039 13.1 0.0 0.77 8.8 0.0 2.1 2 0 0 2 2 2 0 Histidine-specific methyltransferase, SAM-dependent FA_hydroxylase PF04116.13 KKK12816.1 - 1.9e-27 96.2 11.1 1.9e-27 96.2 11.1 2.1 3 0 0 3 3 3 1 Fatty acid hydroxylase superfamily PIG-L PF02585.17 KKK12817.1 - 6.8e-19 68.8 0.3 1.6e-18 67.6 0.3 1.6 1 1 0 1 1 1 1 GlcNAc-PI de-N-acetylase NAD_binding_8 PF13450.6 KKK12818.1 - 2.5e-11 43.6 0.0 1.2e-08 35.0 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KKK12818.1 - 4e-11 42.7 0.0 1.8e-07 30.7 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KKK12818.1 - 1.4e-09 37.6 0.0 1e-08 34.8 0.0 2.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KKK12818.1 - 2.5e-09 36.1 0.0 1.4e-08 33.6 0.0 1.9 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like DAO PF01266.24 KKK12818.1 - 1.2e-07 31.6 0.5 4e-05 23.4 0.1 3.3 3 1 1 4 4 4 1 FAD dependent oxidoreductase Thi4 PF01946.17 KKK12818.1 - 3.9e-07 29.5 0.0 1.1e-05 24.8 0.0 2.1 2 0 0 2 2 2 1 Thi4 family K_oxygenase PF13434.6 KKK12818.1 - 8.8e-06 25.1 0.0 0.0012 18.0 0.0 2.5 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 KKK12818.1 - 1.5e-05 25.4 0.0 0.1 13.2 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KKK12818.1 - 0.003 16.9 0.0 0.0042 16.4 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.12 KKK12818.1 - 0.0053 15.9 0.0 0.41 9.6 0.0 2.5 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 KKK12818.1 - 0.0063 15.6 0.0 0.037 13.1 0.0 2.2 3 0 0 3 3 3 1 FAD binding domain NAD_binding_9 PF13454.6 KKK12818.1 - 0.027 14.5 0.1 3.4 7.6 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding NAD_binding_7 PF13241.6 KKK12818.1 - 0.033 14.6 0.0 0.079 13.4 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding Shikimate_DH PF01488.20 KKK12818.1 - 0.072 13.2 0.0 0.75 9.9 0.0 2.1 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase HI0933_like PF03486.14 KKK12818.1 - 0.11 11.2 0.0 0.47 9.1 0.0 1.8 2 0 0 2 2 2 0 HI0933-like protein GIDA PF01134.22 KKK12818.1 - 0.24 10.4 0.1 0.52 9.3 0.1 1.5 1 0 0 1 1 1 0 Glucose inhibited division protein A adh_short PF00106.25 KKK12820.1 - 4e-37 127.6 0.3 1.1e-36 126.1 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KKK12820.1 - 1.4e-24 87.0 0.0 1.9e-24 86.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KKK12820.1 - 9.3e-07 28.9 0.4 0.0026 17.7 0.1 2.2 2 0 0 2 2 2 2 KR domain Epimerase PF01370.21 KKK12820.1 - 0.00044 19.8 0.0 0.00089 18.8 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family UPF0181 PF03701.14 KKK12820.1 - 0.033 13.8 0.1 0.08 12.6 0.1 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0181) UPF0146 PF03686.13 KKK12820.1 - 0.16 11.8 0.0 0.34 10.8 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0146) Abhydrolase_3 PF07859.13 KKK12821.1 - 6.1e-16 58.9 0.2 1.1e-15 58.0 0.2 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KKK12821.1 - 2.6e-11 43.0 0.0 3.2e-11 42.7 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Fungal_trans PF04082.18 KKK12822.1 - 2.3e-19 69.5 0.2 4.6e-19 68.5 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK12822.1 - 4.2e-07 30.0 7.1 7.8e-07 29.1 7.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pox_A_type_inc PF04508.12 KKK12822.1 - 0.061 13.2 1.4 0.18 11.7 1.4 1.9 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat DUF5588 PF17826.1 KKK12822.1 - 0.098 11.5 0.1 0.22 10.4 0.1 1.5 2 0 0 2 2 2 0 Family of unknown function (DUF5588) DUF2286 PF10051.9 KKK12822.1 - 0.23 11.2 0.0 0.42 10.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2286) Glyco_hydro_28 PF00295.17 KKK12823.1 - 1.9e-47 162.0 6.5 5.8e-46 157.0 6.5 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 28 CDH-cyt PF16010.5 KKK12824.1 - 6.3e-21 74.9 1.4 1e-20 74.2 1.4 1.2 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase Cytochrom_B561 PF03188.16 KKK12824.1 - 4.2e-06 26.9 6.2 4.2e-06 26.9 6.2 2.2 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 DUF2427 PF10348.9 KKK12824.1 - 0.0003 20.6 1.1 0.0003 20.6 1.1 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF2427) DOMON PF03351.17 KKK12824.1 - 0.00068 19.9 0.0 0.0012 19.0 0.0 1.4 1 0 0 1 1 1 1 DOMON domain MIG-14_Wnt-bd PF06664.12 KKK12824.1 - 0.042 13.1 0.0 3.5 6.8 0.0 2.1 1 1 1 2 2 2 0 Wnt-binding factor required for Wnt secretion Ferric_reduct PF01794.19 KKK12824.1 - 1 9.5 6.0 1.1 9.5 2.6 2.5 2 1 0 2 2 2 0 Ferric reductase like transmembrane component DHquinase_I PF01487.15 KKK12825.1 - 7.5e-29 101.6 0.0 1.1e-28 101.0 0.0 1.2 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.22 KKK12825.1 - 1.9e-18 67.1 0.1 5.4e-18 65.6 0.0 1.8 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.11 KKK12825.1 - 7.3e-13 48.6 0.0 2.8e-12 46.7 0.0 2.0 2 0 0 2 2 2 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.20 KKK12825.1 - 2e-08 34.4 0.1 1.5e-07 31.6 0.1 2.1 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase SDH_C PF18317.1 KKK12825.1 - 0.00013 21.7 0.0 0.00028 20.6 0.0 1.5 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain F420_oxidored PF03807.17 KKK12825.1 - 0.064 13.8 0.0 0.17 12.5 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent ABC2_membrane PF01061.24 KKK12826.1 - 4.8e-70 235.2 55.4 2.9e-38 131.4 26.6 2.7 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 KKK12826.1 - 3.6e-31 108.5 0.0 5.1e-16 59.4 0.0 2.9 2 1 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 KKK12826.1 - 1.7e-24 85.5 0.2 1.7e-24 85.5 0.2 3.7 4 0 0 4 4 3 2 CDR ABC transporter ABC2_membrane_3 PF12698.7 KKK12826.1 - 5.4e-09 35.6 38.9 7.3e-05 22.0 13.4 2.4 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_29 PF13555.6 KKK12826.1 - 0.002 17.8 0.3 0.29 10.9 0.1 2.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_25 PF13481.6 KKK12826.1 - 0.0032 17.1 0.0 1.4 8.5 0.0 2.9 3 0 0 3 3 3 1 AAA domain RsgA_GTPase PF03193.16 KKK12826.1 - 0.0053 16.7 0.1 0.41 10.5 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase ABC_trans_N PF14510.6 KKK12826.1 - 0.011 16.4 1.3 0.023 15.3 0.0 2.2 2 0 0 2 2 2 0 ABC-transporter N-terminal AAA_22 PF13401.6 KKK12826.1 - 0.044 14.1 0.3 3.1 8.1 0.1 3.0 3 0 0 3 3 3 0 AAA domain AAA_21 PF13304.6 KKK12826.1 - 0.2 11.4 3.5 0.42 10.4 0.0 2.9 2 1 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 KKK12826.1 - 0.22 11.6 0.1 21 5.2 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase ABC2_membrane_2 PF12679.7 KKK12826.1 - 1.5 8.0 27.9 0.52 9.5 9.3 2.6 2 1 0 2 2 2 0 ABC-2 family transporter protein DUF1752 PF08550.10 KKK12827.1 - 1.2e-10 41.0 4.1 2.3e-10 40.1 4.1 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) SUI1 PF01253.22 KKK12828.1 - 1.6e-22 79.8 1.8 3.2e-22 78.8 1.8 1.5 1 0 0 1 1 1 1 Translation initiation factor SUI1 RcbX PF02341.15 KKK12828.1 - 0.068 13.4 0.0 0.15 12.3 0.0 1.6 1 1 0 1 1 1 0 RbcX protein Fungal_trans PF04082.18 KKK12829.1 - 6.8e-18 64.7 0.0 1.3e-17 63.7 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK12829.1 - 9e-08 32.1 13.8 1.6e-07 31.3 13.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fringe PF02434.16 KKK12830.1 - 1.9e-09 37.3 0.2 2.2e-06 27.3 0.0 3.8 3 1 0 3 3 3 1 Fringe-like PAN_1 PF00024.26 KKK12830.1 - 0.0054 16.7 0.3 0.0099 15.8 0.3 1.4 1 0 0 1 1 1 1 PAN domain Mannosyl_trans3 PF11051.8 KKK12831.1 - 0.022 14.1 0.0 0.035 13.5 0.0 1.2 1 0 0 1 1 1 0 Mannosyltransferase putative Glyco_transf_8 PF01501.20 KKK12831.1 - 0.19 11.2 3.2 1.1 8.8 0.6 2.6 2 1 0 2 2 2 0 Glycosyl transferase family 8 Chromate_transp PF02417.15 KKK12832.1 - 6.5e-60 201.8 32.3 4e-35 121.3 12.5 2.4 3 0 0 3 3 3 2 Chromate transporter Spt5-NGN PF03439.13 KKK12833.1 - 0.0071 16.2 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section DUF3425 PF11905.8 KKK12834.1 - 4.2e-15 55.8 0.0 7.3e-15 55.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 KKK12834.1 - 0.027 14.5 9.3 0.049 13.7 9.3 1.3 1 0 0 1 1 1 0 bZIP transcription factor He_PIG_assoc PF10632.9 KKK12834.1 - 0.2 11.3 0.8 0.39 10.4 0.0 1.9 2 0 0 2 2 2 0 He_PIG associated, NEW1 domain of bacterial glycohydrolase TALPID3 PF15324.6 KKK12835.1 - 0.38 8.4 2.8 0.47 8.1 2.8 1.0 1 0 0 1 1 1 0 Hedgehog signalling target Strep_his_triad PF04270.13 KKK12835.1 - 2.9 8.0 4.3 33 4.6 0.3 2.4 2 0 0 2 2 2 0 Streptococcal histidine triad protein PLA2_B PF01735.18 KKK12836.1 - 6.9e-183 608.5 1.4 8e-183 608.3 1.4 1.0 1 0 0 1 1 1 1 Lysophospholipase catalytic domain Methyltransf_23 PF13489.6 KKK12837.1 - 3.3e-20 72.6 0.0 4.8e-20 72.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKK12837.1 - 8.1e-12 45.7 0.0 2.5e-11 44.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KKK12837.1 - 7.3e-11 42.7 0.0 6.1e-10 39.7 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KKK12837.1 - 1.2e-10 41.9 0.0 2.5e-10 40.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KKK12837.1 - 6.8e-10 38.9 0.0 1.9e-08 34.2 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KKK12837.1 - 0.00069 19.2 0.0 0.0012 18.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 KKK12837.1 - 0.0027 17.1 0.0 0.043 13.1 0.0 2.5 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family PrmA PF06325.13 KKK12837.1 - 0.011 15.1 0.0 0.018 14.5 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.9 KKK12837.1 - 0.018 14.8 0.0 0.028 14.2 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_4 PF02390.17 KKK12837.1 - 0.026 14.0 0.0 0.047 13.2 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase FtsJ PF01728.19 KKK12837.1 - 0.042 14.0 0.0 0.11 12.6 0.0 1.6 1 1 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_2 PF00891.18 KKK12837.1 - 0.046 13.0 0.0 0.083 12.2 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain Fungal_trans_2 PF11951.8 KKK12838.1 - 0.00079 18.3 2.9 0.011 14.6 0.6 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain FAD_binding_4 PF01565.23 KKK12839.1 - 3.3e-13 49.5 0.0 5.4e-13 48.9 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NmrA PF05368.13 KKK12841.1 - 1.3e-37 129.7 0.0 1.6e-37 129.3 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KKK12841.1 - 6.9e-13 48.9 0.1 1e-12 48.3 0.1 1.2 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KKK12841.1 - 1.6e-05 24.1 0.0 2.2e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KKK12841.1 - 3.6e-05 23.3 0.0 5.5e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.18 KKK12841.1 - 0.001 19.3 0.0 0.0016 18.7 0.0 1.3 1 0 0 1 1 1 1 TrkA-N domain Sacchrp_dh_NADP PF03435.18 KKK12841.1 - 0.0095 16.2 0.0 0.027 14.7 0.0 1.7 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 KKK12841.1 - 0.094 13.2 0.0 0.16 12.4 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 KKK12841.1 - 0.2 11.8 0.0 0.33 11.1 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus TspO_MBR PF03073.15 KKK12843.1 - 3.5e-43 146.9 9.9 3.5e-43 146.9 9.9 2.8 3 1 1 4 4 4 1 TspO/MBR family MIP PF00230.20 KKK12843.1 - 1.4e-26 93.6 9.0 2.8e-26 92.6 9.0 1.5 1 0 0 1 1 1 1 Major intrinsic protein Helo_like_N PF17111.5 KKK12845.1 - 0.1 11.9 0.0 0.11 11.8 0.0 1.1 1 0 0 1 1 1 0 Fungal N-terminal domain of STAND proteins DUF3435 PF11917.8 KKK12846.1 - 9.5e-26 90.7 6.7 1.2e-18 67.3 3.6 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3435) DUF1233 PF06806.12 KKK12846.1 - 0.098 12.3 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Putative excisionase (DUF1233) TT_ORF2 PF02957.15 KKK12846.1 - 0.13 13.2 1.4 0.21 12.5 0.4 1.9 1 1 0 1 1 1 0 TT viral ORF2 APH PF01636.23 KKK12847.1 - 4.5e-13 49.7 0.0 2e-12 47.6 0.0 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KKK12847.1 - 3.1e-05 23.4 0.0 0.00029 20.2 0.0 2.3 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family MAP65_ASE1 PF03999.12 KKK12850.1 - 0.1 11.2 0.0 0.12 11.0 0.0 1.2 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Isochorismatase PF00857.20 KKK12859.1 - 5.7e-37 127.6 0.0 2.8e-36 125.3 0.0 2.1 2 1 0 2 2 2 1 Isochorismatase family FAR1 PF03101.15 KKK12859.1 - 5e-05 23.9 0.0 8.8e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 FAR1 DNA-binding domain AFT PF08731.11 KKK12859.1 - 0.076 13.4 0.0 0.13 12.7 0.0 1.3 1 0 0 1 1 1 0 Transcription factor AFT NUDE_C PF04880.13 KKK12860.1 - 1.2e-68 231.1 2.6 1.2e-68 231.1 2.6 4.2 3 1 2 5 5 3 1 NUDE protein, C-terminal conserved region ZapB PF06005.12 KKK12860.1 - 6.8e-05 23.2 7.1 6.8e-05 23.2 7.1 4.7 2 1 3 5 5 5 1 Cell division protein ZapB BAR_2 PF10455.9 KKK12860.1 - 0.0023 17.1 7.7 0.0042 16.3 7.7 1.4 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking TPR_MLP1_2 PF07926.12 KKK12860.1 - 0.0051 16.9 34.4 0.015 15.3 11.5 3.8 2 1 1 4 4 4 2 TPR/MLP1/MLP2-like protein PSII_Pbs27 PF13326.6 KKK12860.1 - 0.0058 17.0 5.7 0.014 15.7 5.7 1.6 1 0 0 1 1 1 1 Photosystem II Pbs27 AKNA PF12443.8 KKK12860.1 - 0.018 15.7 8.3 0.27 11.9 3.3 3.8 3 0 0 3 3 3 0 AT-hook-containing transcription factor Chibby PF14645.6 KKK12860.1 - 0.031 14.7 11.5 1.6 9.2 0.3 2.8 1 1 1 2 2 2 0 Chibby family Alanine_zipper PF11839.8 KKK12860.1 - 0.032 14.6 0.7 0.032 14.6 0.7 2.4 3 0 0 3 3 2 0 Alanine-zipper, major outer membrane lipoprotein LPP PF04728.13 KKK12860.1 - 0.035 14.5 7.3 0.087 13.2 0.4 3.8 4 1 0 4 4 3 0 Lipoprotein leucine-zipper SOGA PF11365.8 KKK12860.1 - 0.037 15.2 5.1 0.037 15.2 5.1 3.9 2 1 1 4 4 3 0 Protein SOGA Tropomyosin_1 PF12718.7 KKK12860.1 - 0.13 12.4 32.3 0.29 11.3 21.2 3.4 2 1 1 3 3 3 0 Tropomyosin like Fez1 PF06818.15 KKK12860.1 - 0.14 12.6 25.0 1.9 8.9 10.5 2.7 2 1 1 3 3 3 0 Fez1 DUF745 PF05335.13 KKK12860.1 - 0.43 10.3 13.0 0.92 9.2 13.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF745) DASH_Duo1 PF08651.10 KKK12860.1 - 0.45 10.3 4.4 2.2 8.1 0.3 3.4 4 0 0 4 4 3 0 DASH complex subunit Duo1 Spc7 PF08317.11 KKK12860.1 - 0.62 8.9 29.1 0.009 14.9 19.4 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein XRN_M PF17846.1 KKK12860.1 - 0.67 8.8 4.3 1.2 8.0 4.3 1.3 1 0 0 1 1 1 0 Xrn1 helical domain ERM PF00769.19 KKK12860.1 - 0.69 9.7 32.2 1.4 8.6 31.5 1.9 2 1 0 2 2 1 0 Ezrin/radixin/moesin family CENP-F_leu_zip PF10473.9 KKK12860.1 - 0.72 9.9 30.0 0.55 10.2 23.6 2.9 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF812 PF05667.11 KKK12860.1 - 0.87 8.4 22.8 1.5 7.6 22.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Cep57_MT_bd PF06657.13 KKK12860.1 - 1.1 9.7 22.2 1.5 9.3 0.9 3.8 2 1 2 4 4 4 0 Centrosome microtubule-binding domain of Cep57 APG6_N PF17675.1 KKK12860.1 - 1.2 9.7 39.0 0.18 12.3 9.9 3.2 1 1 2 3 3 3 0 Apg6 coiled-coil region DMPK_coil PF08826.10 KKK12860.1 - 1.5 9.0 27.0 0.39 10.9 2.1 4.4 3 1 1 4 4 4 0 DMPK coiled coil domain like ADIP PF11559.8 KKK12860.1 - 1.7 8.7 28.5 2 8.5 2.3 3.7 1 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding FPP PF05911.11 KKK12860.1 - 1.8 6.6 25.9 0.13 10.5 12.3 2.1 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil Tho2 PF11262.8 KKK12860.1 - 1.9 7.6 20.8 0.19 10.9 3.4 2.1 1 1 1 2 2 2 0 Transcription factor/nuclear export subunit protein 2 STAT_alpha PF01017.20 KKK12860.1 - 2.1 8.2 12.4 2.8 7.8 5.4 2.7 2 1 0 3 3 3 0 STAT protein, all-alpha domain Filament PF00038.21 KKK12860.1 - 2.3 7.7 27.3 7.5 6.0 27.3 1.9 1 1 0 1 1 1 0 Intermediate filament protein DUF2046 PF09755.9 KKK12860.1 - 2.5 7.2 24.2 0.12 11.6 13.9 2.9 2 1 1 3 3 3 0 Uncharacterized conserved protein H4 (DUF2046) YabA PF06156.13 KKK12860.1 - 3.4 8.4 21.9 0.19 12.4 3.2 3.0 2 1 2 4 4 3 0 Initiation control protein YabA DUF3584 PF12128.8 KKK12860.1 - 3.8 4.9 24.2 5.2 4.5 22.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) CENP-H PF05837.12 KKK12860.1 - 3.8 7.9 23.8 0.29 11.6 11.2 2.9 1 1 2 3 3 3 0 Centromere protein H (CENP-H) GAS PF13851.6 KKK12860.1 - 5.9 6.2 30.3 6.3 6.1 19.2 2.9 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding PRKG1_interact PF15898.5 KKK12860.1 - 6.1 7.8 25.8 57 4.7 17.2 3.1 2 1 1 3 3 2 0 cGMP-dependent protein kinase interacting domain CCDC144C PF14915.6 KKK12860.1 - 6.6 5.7 27.9 44 3.0 27.9 2.1 1 1 0 1 1 1 0 CCDC144C protein coiled-coil region Fmp27_WPPW PF10359.9 KKK12860.1 - 9.2 5.0 17.8 1.1 8.0 11.8 2.1 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain JIP_LZII PF16471.5 KKK12860.1 - 9.9 6.4 19.0 1.8 8.8 0.4 4.0 2 1 1 4 4 4 0 JNK-interacting protein leucine zipper II ACC_central PF08326.12 KKK12861.1 - 1.5e-282 939.2 0.0 1.9e-282 938.9 0.0 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.22 KKK12861.1 - 1.1e-191 637.8 0.0 2.3e-191 636.8 0.0 1.5 2 0 0 2 2 2 1 Carboxyl transferase domain CPSase_L_D2 PF02786.17 KKK12861.1 - 1.8e-51 174.7 0.0 6.5e-51 172.8 0.0 1.9 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 KKK12861.1 - 3.3e-28 98.4 0.1 6.1e-28 97.6 0.1 1.5 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 KKK12861.1 - 6.5e-23 80.9 0.0 1.5e-19 70.1 0.0 3.5 3 0 0 3 3 3 2 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 KKK12861.1 - 4.4e-17 61.7 0.1 1.2e-16 60.3 0.1 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_3 PF02655.14 KKK12861.1 - 0.0035 17.4 0.0 0.012 15.7 0.0 1.9 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 KKK12861.1 - 0.0047 16.5 0.0 0.011 15.2 0.0 1.7 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus GxGYxYP_N PF16216.5 KKK12861.1 - 0.053 13.7 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 GxGYxY sequence motif in domain of unknown function N-terminal ATPgrasp_Ter PF15632.6 KKK12861.1 - 0.16 11.7 0.0 0.39 10.5 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon Sec7 PF01369.20 KKK12862.1 - 3.1e-32 111.7 0.0 5e-32 111.1 0.0 1.2 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.6 KKK12862.1 - 2.6e-08 34.3 0.2 5.7e-08 33.2 0.2 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 KKK12862.1 - 1.4e-05 25.6 0.0 5.2e-05 23.7 0.0 2.1 1 0 0 1 1 1 1 PH domain Zip PF02535.22 KKK12863.1 - 3.9e-23 82.2 1.3 3.9e-23 82.2 1.3 2.0 2 1 0 2 2 2 1 ZIP Zinc transporter DUF2040 PF09745.9 KKK12864.1 - 2.3e-35 121.3 9.9 2.3e-35 121.3 9.9 2.9 2 1 0 2 2 2 1 Coiled-coil domain-containing protein 55 (DUF2040) DUF2756 PF10956.8 KKK12864.1 - 8.8 6.9 7.8 3.1 8.3 3.5 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2756) Sedlin_N PF04628.13 KKK12865.1 - 5.4e-19 68.6 0.0 6.8e-19 68.3 0.0 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Glyco_hydro_16 PF00722.21 KKK12876.1 - 3.7e-10 39.5 0.0 1.9e-09 37.3 0.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 Vps8 PF12816.7 KKK12877.1 - 3.7e-63 212.6 0.1 9.6e-63 211.3 0.1 1.8 2 0 0 2 2 2 1 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.20 KKK12877.1 - 6.1e-06 26.2 0.0 0.16 11.8 0.0 3.1 3 0 0 3 3 3 2 Region in Clathrin and VPS zf-C3H2C3 PF17122.5 KKK12877.1 - 0.00037 20.5 0.3 0.0011 19.0 0.3 1.8 1 0 0 1 1 1 1 Zinc-finger Pox_D3 PF04580.13 KKK12877.1 - 0.029 14.0 0.0 0.055 13.1 0.0 1.3 1 0 0 1 1 1 0 Chordopoxvirinae D3 protein zf-RING_5 PF14634.6 KKK12877.1 - 0.23 11.5 2.0 0.23 11.4 0.3 1.8 2 0 0 2 2 2 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 KKK12877.1 - 0.45 10.6 2.5 0.42 10.7 0.6 2.0 1 1 0 1 1 1 0 RING-type zinc-finger zf-RING_2 PF13639.6 KKK12877.1 - 0.75 10.2 6.1 0.082 13.2 1.1 2.1 2 0 0 2 2 2 0 Ring finger domain Glyco_transf_90 PF05686.12 KKK12878.1 - 5.2e-13 48.7 0.1 6e-07 28.7 0.1 3.2 2 1 0 2 2 2 2 Glycosyl transferase family 90 DEAD PF00270.29 KKK12879.1 - 2.2e-16 60.2 0.0 5e-16 59.0 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KKK12879.1 - 3.4e-09 37.0 0.0 1.3e-08 35.2 0.0 2.1 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KKK12879.1 - 1.9e-08 34.5 0.0 3.4e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HTH_45 PF14947.6 KKK12879.1 - 8.7e-05 22.4 0.1 0.00032 20.6 0.1 1.9 2 0 0 2 2 2 1 Winged helix-turn-helix AAA_22 PF13401.6 KKK12879.1 - 0.008 16.5 0.0 0.08 13.2 0.0 2.6 1 1 0 1 1 1 1 AAA domain DUF4332 PF14229.6 KKK12879.1 - 0.098 12.9 0.1 0.29 11.4 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4332) eIF-3c_N PF05470.12 KKK12884.1 - 1.5e-172 575.0 26.3 1.5e-172 575.0 26.3 3.0 1 1 1 2 2 2 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.27 KKK12884.1 - 4.1e-14 53.0 1.8 8e-13 48.8 0.0 3.3 3 0 0 3 3 3 1 PCI domain SKI PF01202.22 KKK12884.1 - 0.021 14.9 0.1 0.12 12.5 0.0 2.4 2 0 0 2 2 2 0 Shikimate kinase DUF1385 PF07136.11 KKK12884.1 - 0.037 13.3 0.0 0.071 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1385) SDA1 PF05285.12 KKK12884.1 - 0.61 9.5 24.1 1.2 8.5 24.1 1.4 1 0 0 1 1 1 0 SDA1 Ribosomal_L30_N PF08079.12 KKK12885.1 - 5.5e-27 93.8 16.3 9.5e-27 93.1 16.3 1.4 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.20 KKK12885.1 - 6.1e-16 58.1 1.8 6.1e-16 58.1 1.8 1.9 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e PRK PF00485.18 KKK12886.1 - 0.0014 18.4 0.0 0.0024 17.6 0.0 1.4 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family SRP_SPB PF02978.19 KKK12886.1 - 0.064 13.9 0.0 0.12 13.1 0.0 1.4 1 0 0 1 1 1 0 Signal peptide binding domain AAA_16 PF13191.6 KKK12886.1 - 0.08 13.3 0.0 0.42 11.0 0.0 2.1 2 1 1 3 3 3 0 AAA ATPase domain adh_short PF00106.25 KKK12887.1 - 2.2e-85 285.1 8.2 1.6e-46 158.2 0.3 2.4 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KKK12887.1 - 8.7e-68 228.4 2.7 1.7e-35 122.7 0.0 2.4 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase MaoC_dehydratas PF01575.19 KKK12887.1 - 1.7e-34 118.0 0.0 3.3e-34 117.1 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain KR PF08659.10 KKK12887.1 - 1.3e-25 90.4 4.3 8.9e-13 48.5 0.9 2.5 2 1 0 2 2 2 2 KR domain THF_DHG_CYH_C PF02882.19 KKK12887.1 - 1.5e-06 27.6 0.1 9.6e-05 21.7 0.3 2.6 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3HCDH_N PF02737.18 KKK12887.1 - 2.6 7.9 5.7 2.5 7.9 0.8 2.9 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain EAP30 PF04157.16 KKK12888.1 - 6.8e-71 238.3 0.1 7.7e-71 238.1 0.1 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family MarR_2 PF12802.7 KKK12888.1 - 0.12 12.3 0.2 0.48 10.3 0.0 2.1 2 0 0 2 2 2 0 MarR family Pkinase PF00069.25 KKK12889.1 - 2e-49 168.3 0.2 7.9e-49 166.4 0.2 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK12889.1 - 1.6e-22 80.0 0.0 2.7e-22 79.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KKK12889.1 - 0.00042 20.3 0.1 0.00098 19.1 0.1 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 KKK12889.1 - 0.0023 17.6 1.0 0.011 15.4 1.0 1.9 1 1 0 1 1 1 1 RIO1 family Kdo PF06293.14 KKK12889.1 - 0.13 11.6 0.1 0.6 9.4 0.0 2.0 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 KKK12889.1 - 0.41 10.2 2.0 0.5 9.9 0.3 1.9 2 0 0 2 2 2 0 Choline/ethanolamine kinase SNF2_N PF00176.23 KKK12890.1 - 3e-64 216.9 0.0 5.5e-64 216.1 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KKK12890.1 - 3e-18 66.2 0.1 1.5e-17 63.9 0.0 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KKK12890.1 - 3.2e-08 33.8 0.0 2.8e-07 30.7 0.0 2.5 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 KKK12890.1 - 0.0016 17.7 0.0 0.0046 16.2 0.0 1.7 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 TFIIF_beta PF02270.15 KKK12890.1 - 0.0025 17.9 0.0 0.0065 16.6 0.0 1.7 1 0 0 1 1 1 1 TFIIF, beta subunit HTH domain TMCO5 PF14992.6 KKK12890.1 - 0.14 11.7 8.6 0.3 10.6 8.6 1.5 1 0 0 1 1 1 0 TMCO5 family Fungal_TACC PF12709.7 KKK12890.1 - 1.7 9.1 8.1 0.86 10.1 1.3 2.7 2 0 0 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins Transketolase_N PF00456.21 KKK12893.1 - 1.3e-06 27.7 0.0 1.6e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Glyco_hydro_3_C PF01915.22 KKK12894.1 - 1.7e-48 165.3 0.0 2.9e-48 164.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KKK12894.1 - 1.6e-40 139.4 0.0 2.5e-40 138.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KKK12894.1 - 6.5e-21 74.2 0.0 1.2e-20 73.4 0.0 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain Transketolase_C PF02780.20 KKK12895.1 - 1.2e-06 28.4 0.0 7.6e-06 25.8 0.0 2.2 2 0 0 2 2 2 1 Transketolase, C-terminal domain Transket_pyr PF02779.24 KKK12895.1 - 1.7e-05 24.6 0.6 3.5e-05 23.6 0.2 1.8 2 1 0 2 2 2 1 Transketolase, pyrimidine binding domain PITH PF06201.13 KKK12896.1 - 1.9e-37 128.8 0.0 2.9e-37 128.2 0.0 1.3 1 0 0 1 1 1 1 PITH domain Thioredoxin PF00085.20 KKK12896.1 - 1.6e-22 79.4 0.0 3e-22 78.6 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 KKK12896.1 - 1.6e-05 25.2 0.0 0.00084 19.6 0.0 2.5 1 1 1 2 2 2 2 Thioredoxin-like OST3_OST6 PF04756.13 KKK12896.1 - 4.1e-05 23.1 0.0 6.3e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 KKK12896.1 - 0.00087 19.7 0.2 0.0046 17.4 0.2 2.2 1 1 0 1 1 1 1 Thioredoxin-like domain Redoxin PF08534.10 KKK12896.1 - 0.0013 18.5 1.3 0.082 12.6 0.0 2.6 2 1 1 3 3 3 1 Redoxin Thioredoxin_9 PF14595.6 KKK12896.1 - 0.002 17.9 0.0 0.0036 17.1 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.21 KKK12896.1 - 0.0086 16.0 0.8 0.077 12.9 0.1 2.4 2 1 1 3 3 3 1 AhpC/TSA family HyaE PF07449.11 KKK12896.1 - 0.035 14.1 0.1 0.091 12.7 0.0 1.7 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE DSBA PF01323.20 KKK12896.1 - 0.066 13.0 0.2 0.16 11.8 0.1 1.7 1 1 1 2 2 2 0 DSBA-like thioredoxin domain Zn_clus PF00172.18 KKK12929.1 - 9e-07 28.9 7.0 1.9e-06 27.9 7.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain KAAG1 PF15354.6 KKK12929.1 - 0.034 14.7 0.2 0.15 12.6 0.0 2.2 3 0 0 3 3 3 0 Kidney-associated antigen 1 PBP_like_2 PF12849.7 KKK12930.1 - 1.2e-09 38.3 1.7 4.4e-09 36.4 1.3 2.0 1 1 1 2 2 2 1 PBP superfamily domain AAL_decarboxy PF03306.13 KKK12930.1 - 0.042 13.2 0.0 2.6 7.3 0.0 2.4 2 0 0 2 2 2 0 Alpha-acetolactate decarboxylase LysR_substrate PF03466.20 KKK12930.1 - 0.049 13.0 0.0 0.089 12.1 0.0 1.3 1 0 0 1 1 1 0 LysR substrate binding domain MgrB PF13998.6 KKK12931.1 - 2.4 8.1 4.7 1.3 9.0 0.9 2.5 2 0 0 2 2 2 0 MgrB protein PHY PF00360.20 KKK12932.1 - 2.6e-27 95.3 0.0 5.4e-27 94.3 0.0 1.4 1 0 0 1 1 1 1 Phytochrome region HATPase_c PF02518.26 KKK12932.1 - 4.4e-19 69.0 0.1 1.9e-18 67.0 0.1 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KKK12932.1 - 1e-17 64.3 0.1 4.4e-17 62.2 0.0 2.2 2 0 0 2 2 2 1 Response regulator receiver domain GAF PF01590.26 KKK12932.1 - 5.4e-10 40.0 0.3 4.4e-09 37.1 0.0 2.8 3 0 0 3 3 3 1 GAF domain HisKA PF00512.25 KKK12932.1 - 9.9e-10 38.3 1.1 3.9e-09 36.4 0.4 2.4 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_2 PF08446.11 KKK12932.1 - 3.4e-05 24.5 0.0 0.00087 19.9 0.0 3.1 3 0 0 3 3 3 1 PAS fold HATPase_c_2 PF13581.6 KKK12932.1 - 0.0098 15.8 0.0 0.027 14.4 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain p450 PF00067.22 KKK12933.1 - 6e-74 249.5 0.0 7.4e-74 249.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF485 PF04341.12 KKK12933.1 - 0.17 11.8 0.3 18 5.3 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF485 Sugar_tr PF00083.24 KKK12945.1 - 4.9e-41 141.0 17.2 3.8e-28 98.5 2.9 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KKK12945.1 - 1.6e-25 89.8 22.1 1.6e-25 89.8 22.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4231 PF14015.6 KKK12945.1 - 0.24 11.9 0.8 37 4.8 0.1 3.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) Pyr_redox_3 PF13738.6 KKK12946.1 - 4.7e-19 68.8 0.0 6.9e-16 58.4 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KKK12946.1 - 1.3e-15 56.8 0.0 8.4e-13 47.6 0.0 2.1 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KKK12946.1 - 1.6e-12 47.3 0.0 6.7e-10 38.7 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KKK12946.1 - 8.6e-10 38.3 0.0 4.1e-07 29.5 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KKK12946.1 - 2.2e-05 24.6 0.0 0.00016 21.8 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KKK12946.1 - 0.0056 17.2 0.0 0.99 10.0 0.0 2.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KKK12946.1 - 0.2 10.7 0.0 0.57 9.2 0.0 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein Serglycin PF04360.12 KKK12947.1 - 0.00058 19.8 2.5 0.0033 17.4 0.8 2.4 2 0 0 2 2 2 1 Serglycin Corona_nucleoca PF00937.18 KKK12947.1 - 6.5 5.7 10.7 0.024 13.7 1.3 1.6 2 0 0 2 2 2 0 Coronavirus nucleocapsid protein DUF1772 PF08592.11 KKK12948.1 - 3e-21 76.2 5.9 3.3e-21 76.0 5.9 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) TMEM237 PF15383.6 KKK12948.1 - 0.13 11.3 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 237 Glyco_transf_22 PF03901.17 KKK12949.1 - 1.7e-79 268.0 15.5 2.2e-79 267.7 15.5 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family CBM_14 PF01607.24 KKK12950.1 - 1.9e-09 37.5 5.7 3.3e-09 36.8 5.6 1.4 1 1 0 1 1 1 1 Chitin binding Peritrophin-A domain Lustrin_cystein PF14625.6 KKK12950.1 - 0.65 10.4 6.6 0.45 10.9 0.8 2.1 1 1 1 2 2 2 0 Lustrin, cysteine-rich repeated domain Aminotran_3 PF00202.21 KKK12951.1 - 3.6e-120 401.3 0.0 4.2e-120 401.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 KKK12951.1 - 0.0022 17.2 0.0 0.0041 16.3 0.0 1.4 2 0 0 2 2 2 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 KKK12951.1 - 0.011 15.0 0.0 0.02 14.2 0.0 1.4 1 0 0 1 1 1 0 Beta-eliminating lyase Fungal_trans PF04082.18 KKK12952.1 - 1.8e-28 99.3 0.0 3.3e-28 98.5 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain FAA_hydrolase PF01557.18 KKK12953.1 - 2.4e-54 184.3 0.0 2.9e-54 184.0 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.11 KKK12953.1 - 5.8e-21 74.7 0.0 2.2e-20 72.8 0.0 2.0 3 0 0 3 3 3 1 Fumarylacetoacetase N-terminal LANC_like PF05147.13 KKK12954.1 - 0.14 10.8 0.0 0.18 10.3 0.0 1.1 1 0 0 1 1 1 0 Lanthionine synthetase C-like protein Methyltransf_11 PF08241.12 KKK12955.1 - 5.6e-22 78.2 0.0 1.6e-21 76.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKK12955.1 - 1.9e-19 70.2 0.0 5e-19 68.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KKK12955.1 - 5.7e-19 68.4 0.0 9e-19 67.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KKK12955.1 - 9.1e-14 51.6 0.0 1.4e-13 51.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KKK12955.1 - 9.5e-12 45.5 0.0 2.5e-11 44.2 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 KKK12955.1 - 6.2e-11 42.1 0.0 9.5e-11 41.5 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.20 KKK12955.1 - 3.2e-10 39.8 0.0 4.5e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MetW PF07021.12 KKK12955.1 - 0.00011 21.9 0.0 0.00018 21.2 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW MTS PF05175.14 KKK12955.1 - 0.00055 19.5 0.0 0.00098 18.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.6 KKK12955.1 - 0.0019 18.2 0.0 0.0039 17.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KKK12955.1 - 0.0092 15.7 0.0 0.014 15.1 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.13 KKK12955.1 - 0.014 14.8 0.0 0.024 14.0 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) TehB PF03848.14 KKK12955.1 - 0.019 14.4 0.0 0.033 13.6 0.0 1.4 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_8 PF05148.15 KKK12955.1 - 0.023 14.6 0.0 0.39 10.5 0.0 2.2 1 1 0 1 1 1 0 Hypothetical methyltransferase Methyltransf_2 PF00891.18 KKK12955.1 - 0.037 13.3 0.0 0.057 12.7 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain Cas_Csx8 PF09657.10 KKK12955.1 - 0.094 11.7 0.1 3.7 6.4 0.0 2.3 2 0 0 2 2 2 0 CRISPR-associated protein Csx8 (Cas_Csx8) RrnaAD PF00398.20 KKK12955.1 - 0.15 11.1 0.0 0.24 10.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Usp PF00582.26 KKK12964.1 - 2.9e-24 86.2 0.0 5.2e-24 85.4 0.0 1.4 1 0 0 1 1 1 1 Universal stress protein family MIF4G PF02854.19 KKK12965.1 - 8.7e-50 169.3 0.0 8.7e-50 169.3 0.0 1.9 2 0 0 2 2 2 1 MIF4G domain eIF_4G1 PF12152.8 KKK12965.1 - 2.5e-24 85.2 0.5 7.9e-24 83.6 0.5 1.9 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 FAM75 PF14650.6 KKK12966.1 - 0.064 12.8 0.2 0.071 12.6 0.2 1.0 1 0 0 1 1 1 0 FAM75 family Sec3_C PF09763.9 KKK12977.1 - 2.2e-222 740.4 0.4 2.7e-222 740.0 0.4 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.6 KKK12977.1 - 3.9e-28 97.4 0.1 9.5e-28 96.2 0.1 1.7 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Sec3_C_2 PF15278.6 KKK12977.1 - 0.032 14.6 0.3 0.11 12.9 0.3 1.9 1 0 0 1 1 1 0 Sec3 exocyst complex subunit Vps52 PF04129.12 KKK12977.1 - 0.038 12.7 0.4 0.073 11.8 0.4 1.4 1 0 0 1 1 1 0 Vps52 / Sac2 family FUSC PF04632.12 KKK12977.1 - 0.4 9.2 3.6 0.69 8.4 3.6 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family CCDC-167 PF15188.6 KKK12977.1 - 4 7.9 5.2 11 6.4 2.6 2.7 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 SRP40_C PF05022.12 KKK12978.1 - 1e-17 64.7 0.5 4.1e-17 62.8 0.5 2.1 1 0 0 1 1 1 1 SRP40, C-terminal domain DUF2653 PF10850.8 KKK12978.1 - 0.088 13.0 0.0 0.15 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2653) F-box-like PF12937.7 KKK12979.1 - 0.00012 21.9 0.1 0.00034 20.4 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KKK12979.1 - 0.00064 19.5 0.1 0.002 18.0 0.0 1.8 2 0 0 2 2 2 1 F-box domain p450 PF00067.22 KKK12980.1 - 5.5e-50 170.4 0.0 8.9e-50 169.8 0.0 1.2 1 1 0 1 1 1 1 Cytochrome P450 AA_permease_2 PF13520.6 KKK12982.1 - 3e-51 174.6 49.6 4.1e-51 174.2 49.6 1.1 1 0 0 1 1 1 1 Amino acid permease CRAL_TRIO PF00650.20 KKK12982.1 - 1e-47 161.8 0.1 1.8e-47 161.0 0.1 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain AA_permease PF00324.21 KKK12982.1 - 4.7e-23 81.5 46.9 3.2e-22 78.8 46.9 1.9 1 1 0 1 1 1 1 Amino acid permease CRAL_TRIO_N PF03765.15 KKK12982.1 - 1.1e-07 31.9 0.2 2.3e-07 30.9 0.2 1.5 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 KKK12982.1 - 1.2e-07 31.9 0.0 2.2e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Sua5_yciO_yrdC PF01300.18 KKK12983.1 - 2.5e-11 43.4 0.1 6e-09 35.6 0.1 2.2 1 1 0 1 1 1 1 Telomere recombination GDPD PF03009.17 KKK12984.1 - 1.4e-10 41.4 0.0 3.7e-10 40.0 0.0 1.8 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family TauD PF02668.16 KKK12986.1 - 1.8e-51 175.5 0.5 2e-51 175.4 0.5 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Fungal_trans PF04082.18 KKK12987.1 - 3.4e-22 78.8 1.4 5.8e-22 78.0 1.4 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 KKK12987.1 - 8.4e-10 38.6 12.7 6.2e-05 23.2 0.6 2.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KKK12987.1 - 1.6e-08 34.6 13.8 9.3e-08 32.2 4.8 3.2 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KKK12987.1 - 4.4e-07 30.2 7.5 0.0014 19.3 2.0 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-FPG_IleRS PF06827.14 KKK12987.1 - 0.061 13.2 2.1 0.61 10.0 2.1 2.4 1 1 0 1 1 1 0 Zinc finger found in FPG and IleRS zf-C2H2_6 PF13912.6 KKK12987.1 - 0.14 12.2 6.5 0.48 10.5 1.9 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KKK12987.1 - 0.25 11.7 1.9 0.61 10.4 0.3 2.2 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.6 KKK12987.1 - 0.42 10.6 5.5 0.31 11.0 1.0 2.6 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf_UBZ PF18439.1 KKK12987.1 - 0.48 10.1 2.5 7.6 6.2 0.3 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger MFS_1 PF07690.16 KKK12988.1 - 6.6e-42 143.7 30.6 6.6e-42 143.7 30.6 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KKK12988.1 - 1.2e-07 30.6 7.6 1.6e-07 30.2 7.6 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KKK12988.1 - 2.1e-07 30.2 12.1 2.1e-07 30.2 12.1 2.2 1 1 0 2 2 2 1 Sugar (and other) transporter MIP PF00230.20 KKK12989.1 - 9.1e-23 81.1 1.4 1.3e-22 80.6 1.4 1.1 1 0 0 1 1 1 1 Major intrinsic protein Glyco_hydro_28 PF00295.17 KKK12990.1 - 2.4e-120 401.5 20.1 2.7e-120 401.3 20.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 DUF2180 PF09947.9 KKK12990.1 - 0.065 13.2 0.2 0.13 12.3 0.2 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2180) Glyco_hydro_7 PF00840.20 KKK12991.1 - 8.8e-209 693.6 12.0 8.8e-209 693.6 12.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolase family 7 CBM_1 PF00734.18 KKK12991.1 - 4.9e-13 48.8 12.2 4.9e-13 48.8 12.2 3.6 4 0 0 4 4 4 1 Fungal cellulose binding domain Toxin_7 PF05980.12 KKK12991.1 - 5.8 7.3 8.4 0.65 10.3 3.4 2.1 2 0 0 2 2 2 0 Toxin 7 Cellulase PF00150.18 KKK12992.1 - 2.1e-55 188.1 0.2 3.6e-55 187.4 0.2 1.4 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.18 KKK12992.1 - 1e-13 51.0 11.2 1e-13 51.0 11.2 2.4 2 0 0 2 2 2 1 Fungal cellulose binding domain BAF1_ABF1 PF04684.13 KKK12992.1 - 0.3 10.1 4.3 0.32 10.0 4.3 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Mitofilin PF09731.9 KKK12992.1 - 1.9 7.2 9.7 2.6 6.8 9.7 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF1229 PF06797.11 KKK12993.1 - 0.037 14.2 0.7 0.037 14.2 0.7 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1229) Ammonium_transp PF00909.21 KKK12994.1 - 1.9e-74 250.8 19.0 2.6e-74 250.3 19.0 1.1 1 0 0 1 1 1 1 Ammonium Transporter Family Formyl_trans_N PF00551.19 KKK12995.1 - 1e-38 132.9 0.0 1.3e-38 132.6 0.0 1.1 1 0 0 1 1 1 1 Formyl transferase ACT PF01842.25 KKK12995.1 - 9.4e-08 31.7 0.0 2.5e-07 30.3 0.0 1.7 1 0 0 1 1 1 1 ACT domain ACT_6 PF13740.6 KKK12995.1 - 3.3e-06 27.0 0.1 1.4e-05 25.0 0.0 2.2 2 1 0 2 2 2 1 ACT domain DOCK_N PF16172.5 KKK12996.1 - 5e-117 391.0 0.0 9.6e-117 390.1 0.0 1.5 1 0 0 1 1 1 1 DOCK N-terminus DOCK-C2 PF14429.6 KKK12996.1 - 1.9e-36 125.8 0.0 4.2e-36 124.6 0.0 1.7 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins DHR-2 PF06920.13 KKK12996.1 - 2.8e-35 122.0 1.3 9.5e-35 120.2 1.3 1.8 1 1 0 1 1 1 1 Dock homology region 2 SH3_1 PF00018.28 KKK12996.1 - 1.4e-05 24.6 0.0 2.9e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KKK12996.1 - 0.0001 22.1 0.0 0.00087 19.1 0.0 2.2 2 0 0 2 2 2 1 Variant SH3 domain DUF1737 PF08410.10 KKK12996.1 - 0.17 11.7 0.1 0.54 10.2 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1737) Ribosomal_S8e PF01201.22 KKK12997.1 - 2.2e-53 180.1 2.1 3.1e-53 179.6 2.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S8e DUF2470 PF10615.9 KKK12997.1 - 3.2e-20 72.5 0.0 7e-20 71.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) MG4 PF17789.1 KKK12998.1 - 0.19 11.9 0.0 0.35 11.0 0.0 1.4 1 0 0 1 1 1 0 Macroglobulin domain MG4 DUF1516 PF07457.11 KKK12999.1 - 0.021 15.0 1.7 0.021 15.0 1.7 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1516) DUF2818 PF10993.8 KKK12999.1 - 0.59 10.7 4.0 0.76 10.4 0.5 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2818) MRP-L27 PF09809.9 KKK13000.1 - 3.8e-15 55.7 0.2 4.5e-15 55.5 0.2 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 DUF2491 PF10679.9 KKK13000.1 - 0.056 12.6 0.1 0.065 12.4 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2491) DUF4554 PF15091.6 KKK13000.1 - 0.19 10.6 0.0 0.22 10.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) PARP PF00644.20 KKK13001.1 - 4.3e-12 46.0 0.6 1.6e-11 44.2 0.2 1.9 1 1 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain UQ_con PF00179.26 KKK13001.1 - 1.9e-06 27.5 0.0 6.2e-06 25.9 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KKK13001.1 - 0.098 12.9 0.0 0.2 11.9 0.0 1.6 1 0 0 1 1 1 0 RWD domain Glyco_hydro81C PF17652.1 KKK13002.1 - 5.5e-169 561.9 5.9 6.8e-169 561.6 5.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 KKK13002.1 - 2.6e-116 388.3 2.4 3.7e-116 387.8 2.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 N-terminal domain Utp14 PF04615.13 KKK13003.1 - 2e-216 721.1 68.3 2e-216 721.1 68.3 2.1 1 1 1 2 2 2 1 Utp14 protein SPX PF03105.19 KKK13004.1 - 6.1e-39 135.0 7.7 8.5e-27 95.1 0.1 3.3 2 1 1 3 3 3 2 SPX domain Na_sulph_symp PF00939.19 KKK13004.1 - 4.1e-30 105.2 36.9 6.4e-30 104.6 36.9 1.2 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region Ribosomal_S7 PF00177.21 KKK13004.1 - 4.4e-30 104.3 0.0 1e-29 103.1 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e CitMHS PF03600.16 KKK13004.1 - 5.8e-27 94.7 32.5 2e-26 92.9 32.6 1.9 2 0 0 2 2 2 1 Citrate transporter FxsA PF04186.13 KKK13004.1 - 0.045 13.9 5.0 0.23 11.6 4.8 2.4 1 1 0 1 1 1 0 FxsA cytoplasmic membrane protein DUF4220 PF13968.6 KKK13004.1 - 0.23 10.8 1.8 0.74 9.2 1.8 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) Na_Ca_ex PF01699.24 KKK13005.1 - 2.7e-42 144.3 41.3 8.3e-22 77.8 17.3 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Orf78 PF06024.12 KKK13005.1 - 0.54 10.6 2.6 1.2 9.5 0.7 2.4 1 1 1 2 2 2 0 Orf78 (ac78) ATP-synt_8 PF00895.20 KKK13005.1 - 1 9.9 0.0 1 9.9 0.0 3.6 4 0 0 4 4 4 0 ATP synthase protein 8 DUF1129 PF06570.11 KKK13005.1 - 1.3 8.5 8.2 0.29 10.6 3.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1129) Pyr_redox_3 PF13738.6 KKK13006.1 - 5e-13 49.0 0.0 1.4e-12 47.5 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KKK13006.1 - 5.2e-13 48.3 0.0 1.9e-09 36.5 0.0 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 KKK13006.1 - 2.1e-09 37.0 0.0 2e-08 33.8 0.0 2.3 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 KKK13006.1 - 2.7e-08 33.4 0.0 1.3e-06 27.9 0.0 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KKK13006.1 - 4.9e-05 23.4 0.2 0.011 15.7 0.1 2.8 2 1 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KKK13006.1 - 0.00018 21.7 0.0 0.0005 20.2 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KKK13006.1 - 0.00036 19.8 0.1 0.00077 18.8 0.0 1.6 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.27 KKK13006.1 - 0.0015 19.1 0.5 0.81 10.3 0.0 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KKK13006.1 - 0.05 12.3 0.0 10 4.7 0.0 2.6 3 0 0 3 3 3 0 HI0933-like protein FAD_binding_3 PF01494.19 KKK13007.1 - 3.3e-26 92.4 0.2 1.1e-14 54.4 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_3 PF13738.6 KKK13007.1 - 1.2e-06 28.0 0.3 9.6e-06 25.1 0.1 2.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KKK13007.1 - 1.3e-06 27.8 2.3 0.0014 17.9 0.4 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KKK13007.1 - 1e-05 25.6 1.3 6.6e-05 23.1 0.3 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 KKK13007.1 - 1.2e-05 24.8 2.3 0.018 14.4 0.0 2.7 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 KKK13007.1 - 1.8e-05 24.0 1.0 3.1e-05 23.2 1.0 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KKK13007.1 - 0.00031 20.5 1.5 0.0026 17.4 2.1 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KKK13007.1 - 0.002 17.3 0.9 0.53 9.3 0.9 2.3 2 0 0 2 2 2 2 Lycopene cyclase protein Pyr_redox PF00070.27 KKK13007.1 - 0.0035 17.9 1.8 0.029 14.9 0.4 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KKK13007.1 - 0.0065 15.7 0.2 0.012 14.9 0.2 1.3 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 KKK13007.1 - 0.0087 14.8 0.3 0.015 14.0 0.3 1.4 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.22 KKK13007.1 - 0.012 14.7 1.4 0.018 14.1 1.4 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 KKK13007.1 - 0.021 14.1 0.3 0.039 13.3 0.3 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Trp_halogenase PF04820.14 KKK13007.1 - 0.081 11.8 2.3 0.39 9.5 0.3 2.2 2 0 0 2 2 2 0 Tryptophan halogenase NAD_binding_9 PF13454.6 KKK13007.1 - 0.14 12.1 1.8 8.1 6.4 0.0 3.6 3 1 1 4 4 4 0 FAD-NAD(P)-binding FAD_oxidored PF12831.7 KKK13007.1 - 0.69 9.2 3.0 0.41 9.9 1.3 1.5 2 0 0 2 2 2 0 FAD dependent oxidoreductase DUF3237 PF11578.8 KKK13008.1 - 1.4e-30 106.1 0.0 1.7e-30 105.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) Zn_clus PF00172.18 KKK13009.1 - 4.3e-10 39.6 9.7 4.3e-10 39.6 9.7 1.9 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3439 PF11921.8 KKK13009.1 - 0.1 12.6 11.1 0.22 11.5 11.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Opy2 PF09463.10 KKK13009.1 - 1 9.7 11.5 0.16 12.3 3.5 2.9 3 0 0 3 3 3 0 Opy2 protein adh_short_C2 PF13561.6 KKK13010.1 - 7.1e-55 186.1 3.0 1.1e-54 185.5 3.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KKK13010.1 - 3.4e-42 144.1 2.3 5e-42 143.6 2.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KKK13010.1 - 2.2e-06 27.7 0.7 5.7e-06 26.4 0.7 1.6 1 1 0 1 1 1 1 KR domain Ldh_1_N PF00056.23 KKK13010.1 - 0.14 12.3 0.1 0.25 11.4 0.1 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain DUF3611 PF12263.8 KKK13010.1 - 0.21 11.4 5.8 0.12 12.2 2.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3611) DUF2834 PF11196.8 KKK13010.1 - 0.29 11.5 6.2 5.1 7.5 0.3 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2834) ketoacyl-synt PF00109.26 KKK13011.1 - 1.8e-70 237.4 0.0 4.4e-70 236.1 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 KKK13011.1 - 1.6e-48 165.9 0.0 2.6e-48 165.2 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KKK13011.1 - 1.1e-33 115.8 0.7 2.8e-33 114.4 0.7 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 KKK13011.1 - 3.7e-17 62.8 0.0 7.7e-17 61.8 0.0 1.6 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension PS-DH PF14765.6 KKK13011.1 - 2.2e-07 30.4 0.2 3.9e-07 29.6 0.2 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Thiolase_N PF00108.23 KKK13011.1 - 2.4e-05 23.8 0.1 5.6e-05 22.6 0.1 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain ACP_syn_III PF08545.10 KKK13011.1 - 0.0014 18.5 0.3 0.0033 17.3 0.3 1.7 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III DNA_ligase_A_M PF01068.21 KKK13012.1 - 2e-53 181.1 0.1 1.7e-50 171.5 0.0 2.3 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 KKK13012.1 - 3.5e-36 125.1 0.0 7.8e-36 124.0 0.0 1.6 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 KKK13012.1 - 4.9e-19 68.8 0.0 2.1e-18 66.7 0.0 2.2 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 KKK13012.1 - 0.0053 17.1 0.0 0.012 15.9 0.0 1.6 1 0 0 1 1 1 1 RNA ligase Rotamase_2 PF13145.6 KKK13012.1 - 0.12 13.2 4.8 2.5 8.9 1.2 3.3 3 0 0 3 3 3 0 PPIC-type PPIASE domain RINT1_TIP1 PF04437.13 KKK13013.1 - 3.4e-182 606.8 0.0 8e-182 605.6 0.0 1.6 2 0 0 2 2 2 1 RINT-1 / TIP-1 family CRISPR_Cse2 PF09485.10 KKK13013.1 - 0.007 16.9 4.8 0.013 16.0 3.7 2.0 2 0 0 2 2 2 1 CRISPR-associated protein Cse2 (CRISPR_cse2) GCN5L1 PF06320.13 KKK13013.1 - 0.19 11.8 4.2 4.9 7.3 4.9 2.6 2 0 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) Val_tRNA-synt_C PF10458.9 KKK13013.1 - 0.32 11.3 3.7 1.2 9.5 3.7 2.1 1 0 0 1 1 1 0 Valyl tRNA synthetase tRNA binding arm TBCC_N PF16752.5 KKK13013.1 - 0.36 11.3 8.8 1.4 9.4 8.8 2.1 1 0 0 1 1 1 0 Tubulin-specific chaperone C N-terminal domain Exonuc_VII_L PF02601.15 KKK13013.1 - 0.4 10.2 8.0 0.55 9.7 6.5 1.9 2 0 0 2 2 2 0 Exonuclease VII, large subunit ANAPC_CDC26 PF10471.9 KKK13013.1 - 1.2 10.0 6.1 3.3 8.6 6.1 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit CDC26 Fib_alpha PF08702.10 KKK13013.1 - 1.3 9.2 3.3 3.8 7.7 2.6 2.2 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Spc24 PF08286.11 KKK13013.1 - 2.7 8.3 6.4 7.8 6.8 6.1 1.9 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 OmpH PF03938.14 KKK13013.1 - 3.2 8.1 8.3 10 6.5 8.3 1.9 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) TPR_16 PF13432.6 KKK13013.1 - 3.3 8.4 9.0 1.9 9.2 4.6 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat FUSC PF04632.12 KKK13013.1 - 8.3 4.8 8.3 15 4.0 8.3 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family Metallopep PF12044.8 KKK13014.1 - 9.6e-173 574.7 0.0 1.3e-172 574.3 0.0 1.2 1 0 0 1 1 1 1 Putative peptidase family Jacalin PF01419.17 KKK13014.1 - 0.0055 16.6 0.0 0.034 14.1 0.0 2.1 1 1 1 2 2 2 1 Jacalin-like lectin domain Reprolysin_5 PF13688.6 KKK13014.1 - 0.037 14.2 0.5 0.08 13.1 0.5 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12 Whi5 PF08528.11 KKK13015.1 - 0.00082 18.9 0.4 0.0015 18.1 0.4 1.4 1 0 0 1 1 1 1 Whi5 like AAA PF00004.29 KKK13016.1 - 1.3e-18 67.7 0.0 2.2e-18 67.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KKK13016.1 - 0.0025 18.1 0.3 0.012 15.9 0.3 2.1 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KKK13016.1 - 0.056 13.8 0.0 0.14 12.5 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain Zeta_toxin PF06414.12 KKK13016.1 - 0.067 12.5 0.0 0.23 10.7 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin AAA_5 PF07728.14 KKK13016.1 - 0.12 12.4 0.0 0.29 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NACHT PF05729.12 KKK13017.1 - 1e-07 32.1 0.0 2.9e-07 30.6 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KKK13017.1 - 0.0048 17.3 0.0 0.016 15.6 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KKK13017.1 - 0.031 14.5 0.4 0.12 12.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain Cas9-BH PF16593.5 KKK13017.1 - 0.037 13.7 0.2 0.097 12.4 0.2 1.7 1 0 0 1 1 1 0 Bridge helix of CRISPR-associated endonuclease Cas9 adh_short PF00106.25 KKK13018.1 - 2.7e-23 82.4 0.0 1.2e-19 70.6 0.0 2.0 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KKK13018.1 - 1.3e-12 47.8 0.1 1.1e-11 44.7 0.1 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KKK13018.1 - 0.00051 20.0 0.1 0.00079 19.4 0.1 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KKK13018.1 - 0.01 15.0 0.0 0.014 14.5 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein GMC_oxred_N PF00732.19 KKK13020.1 - 1.7e-51 175.3 0.0 2.4e-51 174.9 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KKK13020.1 - 3.3e-33 115.2 0.0 5.5e-33 114.5 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.24 KKK13020.1 - 3.3e-05 23.6 0.0 0.00014 21.6 0.0 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KKK13020.1 - 6.8e-05 22.1 0.0 0.13 11.3 0.2 2.3 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KKK13020.1 - 0.0037 17.5 0.1 0.011 15.9 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KKK13020.1 - 0.0088 15.3 0.2 0.025 13.8 0.1 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KKK13020.1 - 0.0091 15.1 0.0 0.014 14.5 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_4 PF01565.23 KKK13020.1 - 1.6 8.5 3.9 13 5.5 0.4 3.3 3 0 0 3 3 3 0 FAD binding domain THUMP PF02926.17 KKK13021.1 - 2.9e-12 46.9 0.8 5e-12 46.1 0.2 1.6 2 0 0 2 2 2 1 THUMP domain TPP_enzyme_N PF02776.18 KKK13022.1 - 1.9e-32 112.2 0.0 3.3e-32 111.5 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 KKK13022.1 - 3e-22 78.8 0.0 5.9e-22 77.9 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 KKK13022.1 - 5.3e-15 55.5 0.0 1.7e-14 53.9 0.0 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.20 KKK13022.1 - 0.0061 15.5 0.1 0.011 14.8 0.1 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component Pkinase PF00069.25 KKK13023.1 - 5.2e-65 219.4 0.0 7.7e-65 218.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK13023.1 - 8.9e-44 149.7 0.0 1.3e-43 149.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KKK13023.1 - 2.1e-09 37.1 0.0 6.5e-07 28.9 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 KKK13023.1 - 0.0014 17.5 0.0 0.0025 16.7 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KKK13023.1 - 0.014 14.8 0.0 0.024 14.0 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KKK13023.1 - 0.11 12.4 0.0 0.26 11.1 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Sec34 PF04136.15 KKK13024.1 - 2.2e-49 167.2 1.5 4.1e-49 166.3 1.5 1.5 1 0 0 1 1 1 1 Sec34-like family Exo70 PF03081.15 KKK13024.1 - 0.016 14.3 1.8 0.1 11.6 0.0 2.5 3 0 0 3 3 3 0 Exo70 exocyst complex subunit NPV_P10 PF05531.12 KKK13024.1 - 0.092 13.2 0.1 5.4 7.6 0.0 2.9 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein RCC1 PF00415.18 KKK13025.1 - 1.8e-21 76.5 10.8 1.4e-05 25.6 0.2 7.4 7 1 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KKK13025.1 - 1.9e-13 49.8 13.8 1.2e-09 37.7 0.0 5.6 6 0 0 6 6 6 2 Regulator of chromosome condensation (RCC1) repeat SUKH-3 PF14433.6 KKK13025.1 - 0.021 15.3 0.0 2.5 8.6 0.0 3.2 3 0 0 3 3 3 0 SUKH-3 immunity protein PUF PF00806.19 KKK13026.1 - 2.3e-16 58.5 0.0 0.034 13.8 0.0 7.7 8 0 0 8 8 8 5 Pumilio-family RNA binding repeat Pyridoxal_deC PF00282.19 KKK13027.1 - 1.7e-77 260.7 0.0 5.9e-77 258.9 0.0 1.8 2 1 0 2 2 2 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 KKK13027.1 - 2.4e-08 33.3 0.0 3.9e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KKK13027.1 - 2e-05 24.1 0.0 2.4e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase HTH_1 PF00126.27 KKK13027.1 - 0.09 12.7 0.0 0.25 11.3 0.0 1.8 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family SepSecS PF05889.13 KKK13027.1 - 0.14 10.8 0.0 0.27 9.9 0.0 1.4 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS PTR2 PF00854.21 KKK13056.1 - 7.4e-46 156.7 0.7 1.3e-45 156.0 0.7 1.3 1 0 0 1 1 1 1 POT family Pectinesterase PF01095.19 KKK13057.1 - 3.5e-52 177.0 5.7 4.3e-52 176.7 5.7 1.0 1 0 0 1 1 1 1 Pectinesterase Uds1 PF15456.6 KKK13079.1 - 8e-42 142.5 4.7 8e-42 142.5 4.7 6.3 3 1 0 3 3 3 1 Up-regulated During Septation Rab5-bind PF09311.11 KKK13079.1 - 9e-05 22.0 26.0 9e-05 22.0 26.0 5.5 2 1 2 5 5 5 1 Rabaptin-like protein RsgA_GTPase PF03193.16 KKK13079.1 - 0.027 14.4 0.1 0.1 12.5 0.1 2.0 1 0 0 1 1 1 0 RsgA GTPase DUF826 PF05696.11 KKK13079.1 - 0.092 12.8 2.4 12 6.1 0.2 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF826) UBD PF16455.5 KKK13079.1 - 0.22 11.8 0.9 3.6 7.9 0.2 2.9 2 1 0 2 2 2 0 Ubiquitin-binding domain DUF2388 PF09498.10 KKK13079.1 - 0.53 10.3 8.8 46 4.1 0.1 5.1 4 1 0 4 4 4 0 Protein of unknown function (DUF2388) DUF4407 PF14362.6 KKK13079.1 - 1.9 7.7 64.2 0.87 8.9 13.8 5.1 2 1 3 5 5 5 0 Domain of unknown function (DUF4407) TraF_2 PF13729.6 KKK13079.1 - 2.7 7.3 22.4 3 7.1 0.0 5.4 4 1 2 6 6 6 0 F plasmid transfer operon, TraF, protein Bacillus_HBL PF05791.11 KKK13079.1 - 3.2 7.6 19.7 2.4 8.0 2.0 4.6 1 1 4 5 5 5 0 Bacillus haemolytic enterotoxin (HBL) Metallophos PF00149.28 KKK13080.1 - 4e-14 53.6 1.5 6.8e-14 52.8 1.5 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase MFS_1 PF07690.16 KKK13082.1 - 2.1e-22 79.5 45.4 3.2e-22 78.9 45.4 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KKK13082.1 - 0.0045 15.9 35.2 0.051 12.4 35.2 2.3 1 1 0 1 1 1 1 Sugar (and other) transporter ApbA_C PF08546.11 KKK13094.1 - 1.7e-29 102.6 0.0 3.2e-29 101.6 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 KKK13094.1 - 1.7e-25 89.4 0.1 2.4e-25 89.0 0.1 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA AlaDh_PNT_C PF01262.21 KKK13094.1 - 0.034 13.4 0.3 0.066 12.5 0.3 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain CelTOS PF18659.1 KKK13094.1 - 0.071 13.6 0.0 0.21 12.0 0.0 1.7 2 0 0 2 2 2 0 Cell-traversal protein for ookinetes and sporozoites PglD_N PF17836.1 KKK13094.1 - 0.15 12.7 0.6 0.34 11.6 0.1 1.8 2 0 0 2 2 2 0 PglD N-terminal domain Fapy_DNA_glyco PF01149.24 KKK13095.1 - 1.3e-34 119.3 0.1 5.1e-34 117.4 0.0 1.9 2 1 0 2 2 2 1 Formamidopyrimidine-DNA glycosylase N-terminal domain H2TH PF06831.14 KKK13095.1 - 2.4e-21 75.5 0.0 4.9e-21 74.5 0.0 1.4 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain FbpA PF05833.11 KKK13095.1 - 0.012 14.4 0.2 0.019 13.7 0.2 1.5 1 1 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) YL1 PF05764.13 KKK13095.1 - 0.77 9.8 16.0 1.3 9.1 16.0 1.3 1 0 0 1 1 1 0 YL1 nuclear protein DUF2263 PF10021.9 KKK13096.1 - 2.7e-23 83.0 0.0 4.3e-23 82.3 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) Macro PF01661.21 KKK13096.1 - 0.049 13.7 0.0 0.12 12.4 0.0 1.7 1 0 0 1 1 1 0 Macro domain Ribonuc_L-PSP PF01042.21 KKK13097.1 - 1.8e-33 115.1 0.0 2e-33 115.0 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP FMN_dh PF01070.18 KKK13098.1 - 2e-123 411.9 1.3 2.3e-123 411.7 1.3 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 KKK13098.1 - 9.2e-10 38.0 4.5 6.2e-09 35.3 2.5 2.5 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 KKK13098.1 - 1.1e-07 31.4 1.7 2e-05 23.9 0.4 3.0 2 1 1 3 3 3 1 Conserved region in glutamate synthase NMO PF03060.15 KKK13098.1 - 7.8e-07 28.8 0.7 1.2e-06 28.1 0.7 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase ThiG PF05690.14 KKK13098.1 - 4.4e-06 26.2 3.3 0.012 14.9 0.2 3.2 2 1 1 3 3 3 2 Thiazole biosynthesis protein ThiG DHO_dh PF01180.21 KKK13098.1 - 0.00012 21.4 2.2 0.0029 16.9 0.1 2.2 1 1 1 2 2 2 1 Dihydroorotate dehydrogenase His_biosynth PF00977.21 KKK13098.1 - 0.00023 20.7 0.7 0.0012 18.3 0.2 2.3 2 1 1 3 3 3 1 Histidine biosynthesis protein Dus PF01207.17 KKK13098.1 - 0.00025 20.3 0.3 0.016 14.4 0.2 2.2 2 0 0 2 2 2 1 Dihydrouridine synthase (Dus) G3P_antiterm PF04309.12 KKK13098.1 - 0.0078 15.6 0.4 3.8 6.9 0.0 2.9 3 0 0 3 3 3 2 Glycerol-3-phosphate responsive antiterminator PA PF02225.22 KKK13098.1 - 0.035 14.1 0.2 15 5.7 0.0 2.5 2 1 0 2 2 2 0 PA domain PcrB PF01884.17 KKK13098.1 - 0.048 13.1 1.8 1.3 8.4 0.2 2.6 1 1 1 2 2 2 0 PcrB family Cid2 PF09774.9 KKK13099.1 - 4.3e-56 189.8 0.2 5e-56 189.6 0.2 1.0 1 0 0 1 1 1 1 Caffeine-induced death protein 2 CLU PF13236.6 KKK13103.1 - 8.3e-76 254.7 0.0 2.1e-75 253.4 0.0 1.7 2 0 0 2 2 2 1 Clustered mitochondria eIF3_p135 PF12807.7 KKK13103.1 - 4.2e-54 183.2 0.1 1.6e-53 181.4 0.0 2.0 2 0 0 2 2 2 1 Translation initiation factor eIF3 subunit 135 CLU_N PF15044.6 KKK13103.1 - 7e-25 87.2 0.0 2.1e-24 85.6 0.0 1.9 1 0 0 1 1 1 1 Mitochondrial function, CLU-N-term TPR_12 PF13424.6 KKK13103.1 - 1.6e-24 86.0 8.2 4.2e-11 43.0 0.1 4.1 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.6 KKK13103.1 - 9.5e-22 76.2 0.4 3.4e-06 26.7 0.0 5.1 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 KKK13103.1 - 7.4e-05 22.6 1.4 0.38 11.0 0.1 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 KKK13103.1 - 0.00066 19.7 3.1 0.09 13.0 0.5 4.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 KKK13103.1 - 0.0087 16.4 2.7 1.9e+02 2.8 0.0 5.9 6 0 0 6 6 6 0 Tetratricopeptide repeat DUF727 PF05303.12 KKK13103.1 - 0.011 15.8 0.0 0.033 14.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF727) EnY2 PF10163.9 KKK13103.1 - 0.19 12.1 1.2 1.1 9.6 0.2 2.8 2 0 0 2 2 2 0 Transcription factor e(y)2 DUF4746 PF15928.5 KKK13103.1 - 0.57 9.5 4.3 1.1 8.6 4.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DUF2524 PF10732.9 KKK13103.1 - 5.1 7.5 7.6 0.29 11.5 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2524) NAD_binding_6 PF08030.12 KKK13104.1 - 3.4e-20 72.7 0.0 6.5e-18 65.3 0.0 2.2 1 1 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 KKK13104.1 - 1.2e-19 70.7 6.0 1.2e-19 70.7 6.0 2.2 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KKK13104.1 - 4.8e-12 45.9 0.0 5.2e-08 32.9 0.0 2.3 2 0 0 2 2 2 2 FAD-binding domain DUF4405 PF14358.6 KKK13104.1 - 0.23 12.0 11.5 10 6.8 0.1 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4405) HCO3_cotransp PF00955.21 KKK13106.1 - 8.5e-86 288.8 11.3 1e-46 159.9 5.1 2.1 1 1 1 2 2 2 2 HCO3- transporter family SF1-HH PF16275.5 KKK13107.1 - 1.2e-43 148.0 1.3 3e-43 146.8 1.3 1.7 1 0 0 1 1 1 1 Splicing factor 1 helix-hairpin domain GST_N PF02798.20 KKK13107.1 - 8.1e-13 48.5 0.0 1.4e-12 47.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KKK13107.1 - 9.1e-13 48.4 0.0 2.1e-12 47.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KKK13107.1 - 2.4e-11 43.7 0.0 6.5e-11 42.4 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain zf-CCHC PF00098.23 KKK13107.1 - 3.4e-11 42.7 13.7 1.9e-05 24.5 0.8 3.0 3 0 0 3 3 3 2 Zinc knuckle GST_C PF00043.25 KKK13107.1 - 1.7e-09 37.8 0.1 5.1e-09 36.2 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KKK13107.1 - 4.1e-09 36.5 0.0 1.1e-08 35.1 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KKK13107.1 - 2.1e-07 30.8 0.1 4.8e-07 29.7 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain zf-CCHC_3 PF13917.6 KKK13107.1 - 2.7e-06 27.3 5.6 0.0019 18.1 2.8 2.6 1 1 1 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.6 KKK13107.1 - 0.0029 17.3 5.0 0.62 9.8 0.4 2.4 2 0 0 2 2 2 2 Zinc knuckle KH_1 PF00013.29 KKK13107.1 - 0.0037 17.1 0.1 0.0083 15.9 0.1 1.6 1 0 0 1 1 1 1 KH domain zf-CCHC_2 PF13696.6 KKK13107.1 - 0.021 14.7 0.5 0.021 14.7 0.5 2.4 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_6 PF15288.6 KKK13107.1 - 0.084 12.7 12.7 0.52 10.2 0.5 3.4 3 0 0 3 3 3 0 Zinc knuckle Prim_Zn_Ribbon PF08273.12 KKK13107.1 - 5.3 7.4 7.0 1.1 9.6 3.0 1.9 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase eIF3g PF12353.8 KKK13107.1 - 7.5 7.0 11.1 8.3 6.8 0.4 4.1 3 1 1 4 4 4 0 Eukaryotic translation initiation factor 3 subunit G DUF1793 PF08760.11 KKK13108.1 - 5.6e-70 235.1 0.8 8.4e-70 234.5 0.1 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF1793) DUF4965 PF16335.5 KKK13108.1 - 1.8e-63 213.3 1.0 1.2e-49 168.3 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF4965) DUF5127 PF17168.4 KKK13108.1 - 6e-48 163.6 0.2 1.1e-47 162.8 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) DUF4964 PF16334.5 KKK13108.1 - 0.0061 16.1 0.0 0.014 14.9 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4964) DEAD PF00270.29 KKK13109.1 - 5.4e-42 143.5 0.0 9.4e-42 142.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KKK13109.1 - 9.4e-29 100.0 0.0 2.6e-28 98.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KKK13109.1 - 7.1e-06 26.1 0.0 1.3e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit BSP_II PF05432.11 KKK13110.1 - 0.0011 18.8 12.1 0.0011 18.8 12.1 1.8 2 0 0 2 2 2 1 Bone sialoprotein II (BSP-II) SURF2 PF05477.11 KKK13110.1 - 0.031 14.0 10.0 0.06 13.0 10.0 1.5 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) DUF2526 PF10735.9 KKK13110.1 - 1.1 9.5 6.7 2.7 8.2 6.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2526) DNA_pol_phi PF04931.13 KKK13110.1 - 5 5.1 17.6 7.4 4.5 17.6 1.2 1 0 0 1 1 1 0 DNA polymerase phi Terpene_synth_C PF03936.16 KKK13111.1 - 2.2e-05 24.0 0.2 2.2e-05 24.0 0.2 2.1 2 0 0 2 2 2 1 Terpene synthase family, metal binding domain YfbU PF03887.14 KKK13111.1 - 0.081 12.9 0.1 0.37 10.8 0.0 2.0 2 0 0 2 2 2 0 YfbU domain adh_short PF00106.25 KKK13113.1 - 1.1e-23 83.7 0.0 8.1e-23 80.9 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KKK13113.1 - 1.3e-13 51.0 0.1 5.1e-13 49.1 0.0 1.9 2 1 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 KKK13113.1 - 0.0025 17.3 0.1 0.0053 16.3 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KKK13113.1 - 0.013 15.5 0.0 0.025 14.5 0.0 1.4 1 0 0 1 1 1 0 KR domain ATP-synt_F PF01990.17 KKK13113.1 - 0.022 15.0 0.0 0.044 14.1 0.0 1.4 1 0 0 1 1 1 0 ATP synthase (F/14-kDa) subunit Zn_clus PF00172.18 KKK13114.1 - 9.9e-09 35.2 12.1 2.1e-08 34.1 12.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2205 PF10224.9 KKK13135.1 - 9.9e-34 115.2 2.0 9.9e-34 115.2 2.0 1.6 2 0 0 2 2 2 1 Short coiled-coil protein bZIP_1 PF00170.21 KKK13135.1 - 0.0063 16.6 1.7 0.012 15.7 1.7 1.5 1 0 0 1 1 1 1 bZIP transcription factor Spectrin PF00435.21 KKK13135.1 - 0.0097 16.4 1.1 0.015 15.7 1.1 1.3 1 0 0 1 1 1 1 Spectrin repeat DUF2884 PF11101.8 KKK13135.1 - 0.02 14.4 1.2 0.027 14.0 1.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2884) YabA PF06156.13 KKK13135.1 - 0.02 15.5 2.1 0.031 14.9 2.1 1.3 1 0 0 1 1 1 0 Initiation control protein YabA DivIC PF04977.15 KKK13135.1 - 0.025 14.3 1.2 0.04 13.7 1.2 1.3 1 0 0 1 1 1 0 Septum formation initiator HALZ PF02183.18 KKK13135.1 - 0.044 14.0 4.5 0.16 12.2 0.3 2.3 1 1 1 2 2 2 0 Homeobox associated leucine zipper VLPT PF07122.11 KKK13135.1 - 0.054 13.2 0.2 0.15 11.8 0.2 1.7 1 0 0 1 1 1 0 Variable length PCR target protein (VLPT) DUF3450 PF11932.8 KKK13135.1 - 0.072 12.4 3.6 0.09 12.1 3.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) CCDC106 PF15794.5 KKK13135.1 - 0.11 12.1 5.6 0.49 10.1 1.3 2.1 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 LCD1 PF09798.9 KKK13135.1 - 0.14 10.6 4.1 0.17 10.4 4.1 1.0 1 0 0 1 1 1 0 DNA damage checkpoint protein DUF5320 PF17253.2 KKK13135.1 - 0.2 12.7 2.9 0.36 11.9 1.9 2.0 1 1 1 2 2 2 0 Family of unknown function (DUF5320) Alpha-amylase PF00128.24 KKK13136.1 - 2e-45 155.8 0.4 2.6e-45 155.5 0.4 1.0 1 0 0 1 1 1 1 Alpha amylase, catalytic domain RRM_1 PF00076.22 KKK13138.1 - 2.3e-16 59.4 0.0 3.3e-16 58.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KKK13138.1 - 0.0005 19.7 0.0 0.00077 19.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KKK13138.1 - 0.032 14.1 0.0 0.064 13.1 0.0 1.4 1 1 0 1 1 1 0 Occluded RNA-recognition motif RRM_3 PF08777.11 KKK13138.1 - 0.061 13.4 0.0 0.089 12.8 0.0 1.3 1 0 0 1 1 1 0 RNA binding motif Glyco_hydro_76 PF03663.14 KKK13139.1 - 9e-21 74.8 5.1 9e-21 74.8 5.1 2.1 2 1 0 2 2 2 1 Glycosyl hydrolase family 76 ubiquitin PF00240.23 KKK13177.1 - 9.3e-08 31.7 0.0 1.9e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family CCDC53 PF10152.9 KKK13177.1 - 3.5 8.0 8.7 1.1 9.6 4.6 2.2 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex Spore_coat_CotO PF14153.6 KKK13177.1 - 6 6.8 9.9 12 5.8 9.9 1.4 1 0 0 1 1 1 0 Spore coat protein CotO ANAPC10 PF03256.16 KKK13178.1 - 3.1e-41 141.0 0.0 6.9e-41 139.9 0.0 1.5 1 1 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) Rhomboid_SP PF12595.8 KKK13178.1 - 0.045 13.1 0.4 0.085 12.2 0.4 1.4 1 0 0 1 1 1 0 Rhomboid serine protease BSP_II PF05432.11 KKK13178.1 - 0.24 11.1 5.5 0.091 12.5 2.8 1.6 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) PTPRCAP PF15713.5 KKK13178.1 - 1.9 8.8 13.0 0.63 10.3 6.8 2.3 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated PS_Dcarbxylase PF02666.15 KKK13179.1 - 1.6e-79 266.1 0.0 4.1e-79 264.8 0.0 1.6 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase PP2C PF00481.21 KKK13180.1 - 1.3e-32 113.5 0.0 1.5e-27 96.8 0.0 2.4 2 0 0 2 2 2 2 Protein phosphatase 2C CDP-OH_P_transf PF01066.21 KKK13180.1 - 6.1e-13 49.3 0.8 2.5e-12 47.4 0.8 2.2 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase PP2C_2 PF13672.6 KKK13180.1 - 7.2e-05 22.5 0.0 0.00023 20.9 0.0 1.9 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 KKK13180.1 - 0.055 13.4 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Stage II sporulation protein E (SpoIIE) Iso_dh PF00180.20 KKK13181.1 - 4.5e-126 420.7 0.0 5e-126 420.5 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase LSM PF01423.22 KKK13195.1 - 0.052 13.2 0.1 0.06 13.0 0.1 1.1 1 0 0 1 1 1 0 LSM domain Homeodomain PF00046.29 KKK13196.1 - 1.4e-19 69.7 4.5 3.3e-19 68.5 4.5 1.7 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KKK13196.1 - 0.0011 18.8 1.1 0.0024 17.7 1.1 1.6 1 0 0 1 1 1 1 Homeobox KN domain PGP_phosphatase PF09419.10 KKK13197.1 - 4.7e-58 195.5 0.0 6.3e-58 195.1 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.6 KKK13197.1 - 1.2e-05 25.3 0.0 2.1e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 KKK13197.1 - 0.12 12.7 0.4 19 5.5 0.0 2.3 1 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase Aldedh PF00171.22 KKK13199.1 - 2e-156 521.1 0.0 2.3e-156 520.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family GMC_oxred_N PF00732.19 KKK13200.1 - 1.2e-49 169.3 0.0 1.7e-49 168.8 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KKK13200.1 - 6.8e-40 136.9 0.0 1e-39 136.3 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KKK13200.1 - 1.7e-06 27.4 0.0 0.039 13.0 0.0 2.4 3 0 0 3 3 3 2 FAD binding domain Lycopene_cycl PF05834.12 KKK13200.1 - 0.00013 21.1 0.0 0.00019 20.6 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 KKK13200.1 - 0.00049 20.3 0.1 0.0013 18.9 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KKK13200.1 - 0.002 17.7 0.6 0.017 14.7 0.2 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KKK13200.1 - 0.0024 17.1 0.0 0.0083 15.4 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KKK13200.1 - 0.008 15.6 0.4 0.091 12.1 0.0 2.2 2 1 0 2 2 2 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 KKK13200.1 - 0.028 13.3 0.0 0.04 12.8 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox PF00070.27 KKK13200.1 - 0.045 14.3 0.2 1.2 9.7 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KKK13200.1 - 0.1 11.8 0.1 0.49 9.6 0.0 2.0 2 0 0 2 2 2 0 Thi4 family Nitroreductase PF00881.24 KKK13203.1 - 5.6e-15 55.8 0.0 6.7e-15 55.6 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family RTA1 PF04479.13 KKK13204.1 - 2.1e-55 187.5 8.8 2.8e-55 187.1 8.8 1.1 1 0 0 1 1 1 1 RTA1 like protein Zn_clus PF00172.18 KKK13205.1 - 3e-10 40.1 11.3 6.3e-10 39.0 11.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KKK13205.1 - 0.00025 20.0 0.1 0.0004 19.3 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF1422 PF07226.11 KKK13205.1 - 0.12 12.3 0.1 0.27 11.2 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1422) Pec_lyase_C PF00544.19 KKK13206.1 - 4.6e-17 62.3 8.4 5.2e-15 55.6 8.4 2.2 1 1 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 KKK13206.1 - 1.6e-05 24.8 13.4 0.00084 19.2 5.5 2.4 1 1 1 2 2 2 2 Right handed beta helix region MCRA PF06100.11 KKK13207.1 - 3.4e-159 530.8 0.0 4.1e-159 530.6 0.0 1.0 1 0 0 1 1 1 1 MCRA family NAD_binding_8 PF13450.6 KKK13207.1 - 0.00018 21.7 0.1 0.00037 20.6 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KKK13207.1 - 0.0093 15.6 0.9 0.35 10.4 0.4 2.6 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KKK13207.1 - 0.15 12.0 0.1 0.32 11.0 0.1 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding MFS_1 PF07690.16 KKK13208.1 - 8.6e-37 126.9 53.2 5.1e-36 124.3 53.0 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily TMC PF07810.13 KKK13208.1 - 1.2 9.7 7.4 0.14 12.7 2.1 2.1 2 0 0 2 2 2 0 TMC domain Ysc84 PF04366.12 KKK13209.1 - 9.1e-25 86.9 0.0 1.7e-24 86.0 0.0 1.3 1 0 0 1 1 1 1 Las17-binding protein actin regulator DUF3431 PF11913.8 KKK13210.1 - 8.3e-68 228.4 0.0 1.1e-67 228.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) Fungal_trans_2 PF11951.8 KKK13211.1 - 9.6e-14 51.0 0.1 5.9e-13 48.4 0.1 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK13211.1 - 2.6e-06 27.4 12.9 2.6e-06 27.4 12.9 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SIMPL PF04402.14 KKK13212.1 - 8.3e-20 72.1 0.0 1.1e-19 71.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF541) Pkinase PF00069.25 KKK13213.1 - 7e-23 81.3 0.0 3.8e-22 78.9 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK13213.1 - 2.6e-06 26.9 0.3 5e-05 22.7 0.3 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Metallophos PF00149.28 KKK13214.1 - 1.3e-16 61.7 0.3 2.2e-16 60.9 0.3 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Pur_ac_phosph_N PF16656.5 KKK13214.1 - 8.4e-14 51.9 1.5 1.9e-13 50.8 1.5 1.5 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain Metallophos_C PF14008.6 KKK13214.1 - 9.2e-14 52.1 0.0 2.1e-13 50.9 0.0 1.6 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C fn3 PF00041.21 KKK13214.1 - 0.026 14.9 1.7 0.059 13.7 1.7 1.5 1 0 0 1 1 1 0 Fibronectin type III domain PhoD_N PF16655.5 KKK13214.1 - 0.026 15.0 0.3 0.13 12.8 0.1 2.1 2 0 0 2 2 2 0 PhoD-like phosphatase, N-terminal domain Cupin_2 PF07883.11 KKK13214.1 - 0.082 12.6 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 Cupin domain PARP PF00644.20 KKK13215.1 - 2.7e-41 141.3 0.0 1.1e-40 139.3 0.0 1.9 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.14 KKK13215.1 - 8.8e-35 119.8 0.1 1.4e-34 119.1 0.1 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.15 KKK13215.1 - 1.4e-09 37.9 1.1 2.9e-09 36.9 1.1 1.5 1 0 0 1 1 1 1 WGR domain BRCT PF00533.26 KKK13215.1 - 5.4e-08 33.1 0.0 1.3e-07 31.8 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 KKK13215.1 - 6e-05 22.9 0.2 0.00013 21.9 0.2 1.6 1 0 0 1 1 1 1 twin BRCT domain BRCT_2 PF16589.5 KKK13215.1 - 0.00097 19.5 0.0 0.002 18.5 0.0 1.6 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain DUF483 PF04467.12 KKK13215.1 - 0.11 12.5 0.0 14 5.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF483) Glyco_hydro_3_C PF01915.22 KKK13216.1 - 4.6e-45 154.1 0.0 7.2e-45 153.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KKK13216.1 - 1.7e-30 106.5 0.0 2.6e-30 105.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KKK13216.1 - 1e-10 41.6 0.0 1.9e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Cleaved_Adhesin PF07675.11 KKK13216.1 - 0.019 14.9 0.2 0.043 13.8 0.2 1.5 1 0 0 1 1 1 0 Cleaved Adhesin Domain Zn_clus PF00172.18 KKK13217.1 - 2.1e-08 34.1 11.8 4.6e-08 33.0 11.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pyridoxal_deC PF00282.19 KKK13218.1 - 4.7e-98 328.3 0.0 6.1e-98 328.0 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.21 KKK13218.1 - 0.0043 16.4 0.0 0.0061 15.9 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase AMP-binding PF00501.28 KKK13219.1 - 5.2e-29 101.1 0.0 8.4e-29 100.4 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 KKK13219.1 - 8.3e-27 94.0 0.0 1.3e-26 93.3 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 KKK13219.1 - 6.1e-13 48.8 0.0 9.8e-13 48.1 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 KKK13219.1 - 0.00024 21.4 0.0 0.00072 19.9 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site KR PF08659.10 KKK13219.1 - 0.011 15.7 0.0 0.069 13.0 0.1 2.3 2 1 0 2 2 2 0 KR domain GDP_Man_Dehyd PF16363.5 KKK13219.1 - 0.024 14.1 0.0 0.054 12.9 0.0 1.6 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase Glu_dehyd_C PF16912.5 KKK13219.1 - 0.031 13.7 0.0 0.056 12.9 0.0 1.3 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus DXP_reductoisom PF02670.16 KKK13219.1 - 0.14 12.9 0.0 0.3 11.8 0.0 1.6 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Dimerisation PF08100.11 KKK13220.1 - 0.00059 19.8 0.7 0.0018 18.3 0.7 1.9 1 0 0 1 1 1 1 Dimerisation domain Dimerisation2 PF16864.5 KKK13220.1 - 0.0014 18.6 0.0 0.0027 17.6 0.0 1.4 1 0 0 1 1 1 1 Dimerisation domain Methyltransf_2 PF00891.18 KKK13220.1 - 0.081 12.2 0.0 0.19 11.0 0.0 1.6 1 1 0 1 1 1 0 O-methyltransferase domain NAD4L PF06235.11 KKK13221.1 - 2.7 8.0 9.4 0.78 9.8 0.1 2.9 2 1 0 3 3 3 0 NADH dehydrogenase subunit 4L (NAD4L) FAD_binding_2 PF00890.24 KKK13222.1 - 1.4e-62 212.1 0.7 1.7e-62 211.9 0.7 1.0 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KKK13222.1 - 4.8e-11 42.8 0.2 6.9e-09 35.8 0.1 2.7 1 1 1 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KKK13222.1 - 1.9e-09 37.2 0.3 1.4e-08 34.3 0.2 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KKK13222.1 - 9.8e-08 32.1 0.2 3.7e-07 30.3 0.0 2.1 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KKK13222.1 - 1.1e-06 27.6 0.7 0.0047 15.7 0.2 3.1 3 0 0 3 3 3 2 HI0933-like protein GIDA PF01134.22 KKK13222.1 - 8.3e-06 25.1 3.3 0.0014 17.8 0.3 2.9 3 0 0 3 3 3 2 Glucose inhibited division protein A FAD_binding_3 PF01494.19 KKK13222.1 - 0.00016 21.1 0.9 0.00026 20.4 0.3 1.6 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.7 KKK13222.1 - 0.00016 21.1 0.4 0.00038 19.9 0.2 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 KKK13222.1 - 0.00021 20.6 0.5 0.0021 17.4 0.2 2.2 2 0 0 2 2 2 1 Thi4 family Pyr_redox_3 PF13738.6 KKK13222.1 - 0.00077 18.8 0.2 0.54 9.4 0.1 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KKK13222.1 - 0.0065 17.0 0.3 0.043 14.4 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KKK13222.1 - 0.021 13.9 0.4 0.061 12.4 0.1 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 KKK13222.1 - 0.031 13.5 0.2 0.055 12.8 0.2 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Amino_oxidase PF01593.24 KKK13222.1 - 0.033 13.5 0.0 0.19 11.0 0.0 2.0 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase NAD_binding_7 PF13241.6 KKK13222.1 - 0.04 14.4 0.0 0.091 13.2 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding 3HCDH_N PF02737.18 KKK13222.1 - 0.052 13.4 0.1 0.091 12.6 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain MFS_1 PF07690.16 KKK13223.1 - 4.9e-51 173.7 46.2 4.9e-51 173.7 46.2 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KKK13223.1 - 4.4e-21 74.9 22.6 6.7e-21 74.3 22.6 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KKK13223.1 - 3.8e-14 52.4 8.3 3.8e-14 52.4 8.3 2.8 2 1 0 2 2 2 1 Sugar (and other) transporter DUF543 PF04418.12 KKK13223.1 - 2 8.5 9.7 11 6.1 0.3 4.1 3 1 1 4 4 4 0 Domain of unknown function (DUF543) OATP PF03137.20 KKK13223.1 - 4.1 5.6 12.6 0.1 10.9 1.4 2.7 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Arrestin_C PF02752.22 KKK13224.1 - 5.7e-11 43.0 0.2 2e-10 41.2 0.1 1.8 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Fungal_trans PF04082.18 KKK13225.1 - 2.9e-11 42.9 0.1 5.4e-11 42.0 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK13225.1 - 0.14 12.3 6.7 0.28 11.3 6.7 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Ank_2 PF12796.7 KKK13226.1 - 1e-45 154.2 0.5 7.9e-14 52.0 0.0 3.9 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KKK13226.1 - 4.9e-36 122.7 2.2 2e-10 41.0 0.0 4.8 3 2 3 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 KKK13226.1 - 2.9e-30 103.9 5.0 2.2e-07 31.0 0.0 5.9 2 2 4 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 KKK13226.1 - 1e-27 93.1 0.5 3.9e-05 23.7 0.0 7.4 7 0 0 7 7 7 4 Ankyrin repeat Ank PF00023.30 KKK13226.1 - 1.6e-26 91.5 11.1 4.8e-05 23.6 0.0 7.2 7 0 0 7 7 7 5 Ankyrin repeat F-box-like PF12937.7 KKK13226.1 - 0.077 12.9 0.6 0.18 11.7 0.6 1.6 1 0 0 1 1 1 0 F-box-like FA_hydroxylase PF04116.13 KKK13227.1 - 3.9e-25 88.7 14.4 3.9e-25 88.7 14.4 2.1 2 0 0 2 2 2 2 Fatty acid hydroxylase superfamily bZIP_1 PF00170.21 KKK13228.1 - 6e-06 26.3 0.6 1.3e-05 25.2 0.6 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KKK13228.1 - 0.095 12.8 1.2 0.23 11.5 1.2 1.6 1 0 0 1 1 1 0 Basic region leucine zipper CDC45 PF02724.14 KKK13228.1 - 0.14 10.4 1.1 0.19 10.0 1.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Epimerase PF01370.21 KKK13229.1 - 8e-16 58.2 0.4 5.5e-15 55.5 0.4 2.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KKK13229.1 - 5.4e-11 42.5 0.0 1.4e-10 41.1 0.0 1.6 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KKK13229.1 - 3.6e-09 36.0 0.0 4.7e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KKK13229.1 - 7.1e-07 28.7 0.0 0.014 14.6 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.6 KKK13229.1 - 1.2e-06 28.5 0.1 3.2e-06 27.2 0.1 1.7 2 0 0 2 2 2 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 KKK13229.1 - 6.7e-05 22.2 0.0 0.0001 21.5 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.13 KKK13229.1 - 0.0001 22.0 0.0 0.00017 21.3 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.25 KKK13229.1 - 0.0071 15.8 0.0 0.02 14.4 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase MFS_1 PF07690.16 KKK13230.1 - 5e-33 114.5 56.9 1.3e-24 86.8 31.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KKK13230.1 - 0.00022 20.2 43.7 0.0077 15.1 17.0 3.1 2 1 1 3 3 3 3 Sugar (and other) transporter ADH_zinc_N_2 PF13602.6 KKK13231.1 - 4.7e-16 60.0 0.1 7.8e-16 59.3 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KKK13231.1 - 3.1e-12 46.6 0.1 5.2e-12 45.9 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KKK13231.1 - 0.00013 21.9 0.0 0.00027 20.8 0.0 1.6 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.25 KKK13231.1 - 0.0068 15.9 0.0 0.039 13.4 0.1 2.1 2 0 0 2 2 2 1 short chain dehydrogenase ADH_N_2 PF16884.5 KKK13231.1 - 0.052 13.4 0.3 0.11 12.4 0.3 1.5 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase Epimerase PF01370.21 KKK13231.1 - 0.057 12.9 0.1 0.084 12.3 0.1 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KKK13231.1 - 0.07 12.2 0.0 0.16 11.0 0.0 1.6 1 0 0 1 1 1 0 RmlD substrate binding domain Glyco_hydro_16 PF00722.21 KKK13232.1 - 2.5e-07 30.3 1.8 9.5e-07 28.5 0.0 2.7 3 1 1 4 4 4 1 Glycosyl hydrolases family 16 Glyco_hydro_61 PF03443.14 KKK13233.1 - 9.9e-50 169.3 0.0 1.7e-49 168.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Fungal_trans PF04082.18 KKK13234.1 - 9.7e-11 41.2 0.0 1.3e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_43 PF04616.14 KKK13235.1 - 1.7e-42 145.7 5.6 1.9e-42 145.5 5.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Glyco_hydro_2_N PF02837.18 KKK13236.1 - 3.4e-11 43.4 0.2 1.1e-10 41.7 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.21 KKK13236.1 - 7.6e-09 36.2 2.4 9.6e-07 29.5 0.0 2.4 2 0 0 2 2 2 2 Glycosyl hydrolases family 2 Glyco_hydro_2_C PF02836.17 KKK13236.1 - 9.8e-09 34.7 0.1 8.2e-08 31.7 0.1 2.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain HLH PF00010.26 KKK13238.1 - 3.4e-07 30.1 1.2 7.5e-07 29.0 1.2 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF615 PF04751.14 KKK13238.1 - 0.058 13.4 1.4 0.093 12.7 1.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF615) adh_short PF00106.25 KKK13239.1 - 2.7e-49 167.3 0.0 3.8e-49 166.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KKK13239.1 - 6.7e-39 133.8 0.0 8.4e-39 133.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KKK13239.1 - 1.4e-07 31.6 0.0 1.9e-07 31.2 0.0 1.1 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 KKK13239.1 - 5e-05 22.8 0.0 6.8e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 KKK13239.1 - 0.0011 18.4 0.1 0.0027 17.2 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KKK13239.1 - 0.0023 17.6 0.1 0.063 12.8 0.1 2.0 2 0 0 2 2 2 1 NmrA-like family RmlD_sub_bind PF04321.17 KKK13239.1 - 0.19 10.8 0.0 0.31 10.1 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain DIOX_N PF14226.6 KKK13240.1 - 7.7e-25 87.9 0.1 1.2e-24 87.4 0.1 1.2 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KKK13240.1 - 1.1e-13 51.5 0.0 7.2e-13 48.9 0.0 2.3 2 1 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DUF3433 PF11915.8 KKK13241.1 - 1.4e-32 112.0 22.5 1.9e-18 66.7 3.6 3.7 4 0 0 4 4 4 2 Protein of unknown function (DUF3433) ABC2_membrane_2 PF12679.7 KKK13241.1 - 0.39 10.0 5.4 0.58 9.4 3.8 2.2 2 0 0 2 2 2 0 ABC-2 family transporter protein RNA_pol_A_bac PF01000.26 KKK13243.1 - 6.4e-32 110.2 0.0 1e-31 109.6 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 KKK13243.1 - 7.4e-17 60.6 0.0 9.8e-17 60.2 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain NUDIX PF00293.28 KKK13244.1 - 1.4e-16 60.7 0.1 1.7e-16 60.4 0.1 1.1 1 0 0 1 1 1 1 NUDIX domain Cytochrom_C PF00034.21 KKK13245.1 - 7.3e-12 46.3 0.1 1.2e-11 45.6 0.1 1.3 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 KKK13245.1 - 3.6e-07 30.4 2.2 4.5e-06 26.9 2.2 2.1 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 KKK13245.1 - 7.4e-05 22.5 0.1 0.00017 21.3 0.0 1.6 2 0 0 2 2 2 1 Cytochrome c-550 domain Cytochrome-c551 PF10643.9 KKK13245.1 - 0.017 14.7 0.1 0.019 14.6 0.1 1.2 1 0 0 1 1 1 0 Photosystem P840 reaction-centre cytochrome c-551 Haem_bd PF14376.6 KKK13245.1 - 0.086 12.8 0.1 0.14 12.1 0.1 1.3 1 0 0 1 1 1 0 Haem-binding domain Baculo_PEP_C PF04513.12 KKK13246.1 - 0.11 12.5 2.7 0.32 11.1 0.1 2.4 1 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus RNase_PH PF01138.21 KKK13247.1 - 2.9e-06 27.8 0.0 1.1e-05 25.9 0.0 1.9 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KKK13247.1 - 0.023 14.7 0.0 0.74 9.9 0.0 2.3 2 0 0 2 2 2 0 3' exoribonuclease family, domain 2 PRP3 PF08572.10 KKK13248.1 - 0.0077 16.0 0.4 0.013 15.3 0.4 1.4 1 1 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) Fmp27 PF10344.9 KKK13248.1 - 0.18 9.8 0.0 0.23 9.5 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial protein from FMP27 ATE_C PF04377.15 KKK13249.1 - 3.8e-49 166.7 2.6 6.5e-49 166.0 2.6 1.4 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.13 KKK13249.1 - 1.5e-17 63.7 0.5 1.5e-17 63.7 0.5 2.1 2 1 0 2 2 2 1 Arginine-tRNA-protein transferase, N terminus Acetyltransf_6 PF13480.7 KKK13249.1 - 6.1e-05 23.2 0.1 0.00011 22.3 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Kelch_2 PF07646.15 KKK13249.1 - 0.0048 16.8 0.2 0.25 11.4 0.0 2.6 2 0 0 2 2 2 1 Kelch motif Calcipressin PF04847.12 KKK13250.1 - 1.4e-34 119.5 0.3 2.2e-34 118.8 0.3 1.3 1 0 0 1 1 1 1 Calcipressin tRNA-synt_2d PF01409.20 KKK13251.1 - 1.9e-47 161.8 0.4 1.2e-25 90.4 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.14 KKK13251.1 - 1.4e-28 99.1 0.0 4.4e-28 97.5 0.0 1.9 2 0 0 2 2 2 1 Ferredoxin-fold anticodon binding domain GrpE PF01025.19 KKK13252.1 - 2.4e-39 134.6 5.1 3.4e-39 134.2 5.1 1.2 1 0 0 1 1 1 1 GrpE Mito_carr PF00153.27 KKK13253.1 - 4.3e-59 196.4 0.4 3.4e-19 68.5 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Urm1 PF09138.11 KKK13276.1 - 8e-36 122.3 0.1 9.5e-36 122.1 0.1 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.20 KKK13276.1 - 0.00084 19.9 0.0 0.0011 19.5 0.0 1.3 1 0 0 1 1 1 1 ThiS family Porin_3 PF01459.22 KKK13277.1 - 5.7e-85 285.1 0.2 6.6e-85 284.8 0.2 1.0 1 0 0 1 1 1 1 Eukaryotic porin Zds_C PF08632.10 KKK13277.1 - 0.01 15.6 0.0 0.021 14.6 0.0 1.5 1 0 0 1 1 1 0 Activator of mitotic machinery Cdc14 phosphatase activation C-term FH2 PF02181.23 KKK13278.1 - 1.8e-91 307.1 3.3 2.1e-91 306.8 3.3 1.1 1 0 0 1 1 1 1 Formin Homology 2 Domain Nrap_D6 PF17407.2 KKK13278.1 - 0.08 13.2 0.5 0.64 10.2 0.2 2.2 2 0 0 2 2 2 0 Nrap protein domain 6 TrmE_N PF10396.9 KKK13279.1 - 1.3e-36 125.4 0.0 3.2e-36 124.1 0.0 1.7 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus MnmE_helical PF12631.7 KKK13279.1 - 6.3e-28 98.4 0.0 1.5e-27 97.1 0.0 1.7 1 1 0 1 1 1 1 MnmE helical domain MMR_HSR1 PF01926.23 KKK13279.1 - 1.5e-17 63.7 0.0 2.3e-17 63.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KKK13279.1 - 1.7e-05 24.4 0.0 0.00077 19.1 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 KKK13279.1 - 2.6e-05 23.8 0.0 0.00015 21.3 0.0 2.1 2 1 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 KKK13279.1 - 0.00015 21.8 0.0 0.00025 21.1 0.0 1.3 1 0 0 1 1 1 1 Dynamin family Glyco_hydro_3_C PF01915.22 KKK13279.1 - 0.0021 18.1 0.0 0.0031 17.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain AAA_24 PF13479.6 KKK13279.1 - 0.0029 17.3 0.0 0.0087 15.8 0.0 1.8 2 0 0 2 2 2 1 AAA domain Roc PF08477.13 KKK13279.1 - 0.092 13.0 0.1 0.23 11.7 0.0 1.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Ank_2 PF12796.7 KKK13280.1 - 1.3e-65 218.0 4.9 1.3e-15 57.7 0.0 6.8 2 2 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KKK13280.1 - 7.4e-56 185.9 16.9 1.3e-09 38.4 0.1 8.2 5 1 4 9 9 9 9 Ankyrin repeats (many copies) Ank PF00023.30 KKK13280.1 - 6.3e-49 162.4 22.5 3.1e-05 24.2 0.0 13.7 13 0 0 13 13 13 10 Ankyrin repeat Ank_3 PF13606.6 KKK13280.1 - 7e-44 142.8 11.8 0.0026 18.1 0.0 14.1 14 0 0 14 14 14 9 Ankyrin repeat Ank_5 PF13857.6 KKK13280.1 - 4.7e-36 122.4 18.6 4.1e-06 27.0 0.0 11.0 3 3 9 12 12 12 7 Ankyrin repeats (many copies) Helo_like_N PF17111.5 KKK13280.1 - 0.0037 16.7 0.2 0.0066 15.8 0.2 1.5 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins Aconitase PF00330.20 KKK13281.1 - 1.4e-110 370.5 0.2 8.3e-110 367.9 0.2 1.9 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KKK13281.1 - 5.5e-26 91.4 0.0 9.1e-26 90.7 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain NAD_binding_1 PF00175.21 KKK13281.1 - 1e-07 32.5 0.0 0.0081 16.8 0.0 2.5 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KKK13281.1 - 4.2e-05 23.8 0.0 9.1e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 KKK13281.1 - 0.0046 17.1 0.0 0.0098 16.0 0.0 1.6 1 0 0 1 1 1 1 Ferric reductase NAD binding domain 6PF2K PF01591.18 KKK13282.1 - 1.3e-41 142.4 0.0 2e-41 141.7 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase WD40 PF00400.32 KKK13282.1 - 1.7e-24 85.6 13.9 0.00019 22.1 0.0 9.4 11 0 0 11 11 11 7 WD domain, G-beta repeat His_Phos_1 PF00300.22 KKK13282.1 - 2.5e-19 69.8 0.6 1.7e-18 67.0 0.2 2.4 2 1 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 KKK13282.1 - 0.011 15.9 0.0 0.037 14.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KKK13283.1 - 1.8e-16 60.9 0.1 1.4e-15 58.0 0.1 2.2 2 1 0 2 2 1 1 ABC transporter AAA_21 PF13304.6 KKK13283.1 - 3.7e-10 40.1 2.0 0.00026 20.9 0.2 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KKK13283.1 - 0.0019 18.7 1.3 0.0022 18.5 0.4 1.5 2 0 0 2 2 1 1 AAA domain AAA_29 PF13555.6 KKK13283.1 - 0.0021 17.7 0.1 0.0039 16.9 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain PduV-EutP PF10662.9 KKK13283.1 - 0.0059 16.3 0.0 0.0091 15.7 0.0 1.3 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation DUF3584 PF12128.8 KKK13283.1 - 0.0067 14.0 0.1 0.0088 13.6 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) AAA_15 PF13175.6 KKK13283.1 - 0.01 15.6 0.2 0.016 15.0 0.2 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_28 PF13521.6 KKK13283.1 - 0.012 15.8 0.1 0.025 14.8 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KKK13283.1 - 0.015 15.6 0.6 0.049 14.0 0.6 1.8 1 1 0 1 1 1 0 AAA ATPase domain SMC_N PF02463.19 KKK13283.1 - 0.016 14.6 0.0 2.6 7.4 0.0 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_25 PF13481.6 KKK13283.1 - 0.021 14.4 0.0 0.038 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain Roc PF08477.13 KKK13283.1 - 0.027 14.7 0.0 0.057 13.6 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase SRP54 PF00448.22 KKK13283.1 - 0.029 14.0 0.1 0.047 13.3 0.1 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain RsgA_GTPase PF03193.16 KKK13283.1 - 0.038 13.9 0.1 0.062 13.2 0.1 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_33 PF13671.6 KKK13283.1 - 0.045 13.9 0.1 0.11 12.7 0.1 1.7 2 0 0 2 2 2 0 AAA domain AAA_13 PF13166.6 KKK13283.1 - 0.083 11.5 0.1 0.12 11.0 0.1 1.1 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 KKK13283.1 - 0.084 13.3 0.0 0.26 11.7 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Arf PF00025.21 KKK13283.1 - 0.09 12.2 0.1 0.21 11.1 0.1 1.5 1 0 0 1 1 1 0 ADP-ribosylation factor family AAA_14 PF13173.6 KKK13283.1 - 0.2 11.7 0.0 0.64 10.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain IPPT PF01715.17 KKK13284.1 - 2.9e-62 210.5 0.1 5e-62 209.7 0.1 1.3 1 0 0 1 1 1 1 IPP transferase zf-met PF12874.7 KKK13284.1 - 1.1e-06 28.9 0.7 1.9e-06 28.0 0.7 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KKK13284.1 - 1.4e-06 28.4 1.0 2.7e-06 27.5 1.0 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding AAA_33 PF13671.6 KKK13284.1 - 7.3e-05 22.9 0.3 0.086 13.0 0.0 3.4 4 1 0 4 4 4 2 AAA domain AAA_16 PF13191.6 KKK13284.1 - 0.00082 19.8 0.1 0.0074 16.7 0.0 2.6 2 2 0 2 2 2 1 AAA ATPase domain IPT PF01745.16 KKK13284.1 - 0.0018 17.7 0.0 0.0045 16.4 0.0 1.6 1 0 0 1 1 1 1 Isopentenyl transferase AAA_25 PF13481.6 KKK13284.1 - 0.0033 17.0 0.0 0.013 15.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KKK13284.1 - 0.0056 17.2 0.0 0.18 12.4 0.0 2.9 3 0 0 3 3 3 1 AAA domain FAM193_C PF15914.5 KKK13284.1 - 0.0057 16.4 0.2 0.47 10.2 0.0 2.6 2 0 0 2 2 2 1 FAM193 family C-terminal Cytidylate_kin PF02224.18 KKK13284.1 - 0.019 14.7 0.0 0.066 12.9 0.0 1.9 2 0 0 2 2 2 0 Cytidylate kinase AAA_22 PF13401.6 KKK13284.1 - 0.044 14.1 0.0 0.11 12.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.17 KKK13284.1 - 0.053 13.6 0.3 0.92 9.6 0.1 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain zf-C2H2_2 PF12756.7 KKK13284.1 - 0.067 13.5 0.7 0.13 12.6 0.7 1.4 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) AAA_28 PF13521.6 KKK13284.1 - 0.086 13.1 1.2 0.44 10.8 0.0 2.6 3 1 0 3 3 3 0 AAA domain Ploopntkinase3 PF18751.1 KKK13284.1 - 0.088 12.7 0.8 1.1 9.2 0.0 2.6 3 0 0 3 3 3 0 P-loop Nucleotide Kinase3 AKAP95 PF04988.12 KKK13284.1 - 0.13 12.5 1.1 0.31 11.3 0.2 2.1 3 0 0 3 3 3 0 A-kinase anchoring protein 95 (AKAP95) ABC_tran PF00005.27 KKK13284.1 - 0.42 11.1 2.4 0.51 10.8 0.4 2.6 2 1 0 2 2 1 0 ABC transporter RAI1 PF08652.11 KKK13285.1 - 6.2e-30 103.2 0.1 1.3e-29 102.2 0.1 1.5 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease DUF410 PF04190.13 KKK13286.1 - 3.4e-84 282.6 0.0 4.5e-84 282.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF410) Rep_fac_C PF08542.11 KKK13288.1 - 2.3e-22 79.2 0.0 5.7e-22 77.9 0.0 1.7 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 KKK13288.1 - 2.6e-13 50.1 0.0 6.1e-10 39.1 0.0 2.2 1 1 1 2 2 2 2 DNA polymerase III, delta subunit AAA PF00004.29 KKK13288.1 - 1.4e-11 45.0 0.0 2.2e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 KKK13288.1 - 5.9e-07 29.6 0.0 2.2e-06 27.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KKK13288.1 - 6.2e-06 26.7 0.0 0.00072 20.0 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain Viral_helicase1 PF01443.18 KKK13288.1 - 1.1e-05 25.3 0.0 1.8e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 KKK13288.1 - 5.5e-05 23.4 0.0 0.055 13.8 0.0 2.6 2 1 1 3 3 2 2 AAA domain RuvB_N PF05496.12 KKK13288.1 - 0.00014 21.6 0.0 0.00032 20.5 0.0 1.6 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain DNA_pol3_delta PF06144.13 KKK13288.1 - 0.00039 20.2 0.0 0.00057 19.7 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_3 PF07726.11 KKK13288.1 - 0.00045 20.1 0.0 0.00084 19.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 KKK13288.1 - 0.0016 17.8 0.0 0.019 14.3 0.0 2.1 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI Rad17 PF03215.15 KKK13288.1 - 0.0019 18.1 0.0 0.0036 17.2 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_assoc_2 PF16193.5 KKK13288.1 - 0.0054 17.0 0.0 0.014 15.7 0.0 1.8 1 0 0 1 1 1 1 AAA C-terminal domain MeaB PF03308.16 KKK13288.1 - 0.01 14.8 0.0 0.018 14.0 0.0 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_11 PF13086.6 KKK13288.1 - 0.011 15.5 0.0 0.02 14.7 0.0 1.3 1 1 0 1 1 1 0 AAA domain DUF5119 PF17145.4 KKK13288.1 - 0.014 15.4 0.0 1.7 8.6 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5119) AAA_24 PF13479.6 KKK13288.1 - 0.018 14.7 0.0 0.11 12.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain TniB PF05621.11 KKK13288.1 - 0.018 14.4 0.0 3.4 7.0 0.0 2.4 2 0 0 2 2 2 0 Bacterial TniB protein AAA_19 PF13245.6 KKK13288.1 - 0.032 14.6 0.1 0.14 12.5 0.1 1.9 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 KKK13288.1 - 0.036 14.0 0.2 0.16 11.9 0.1 2.1 1 1 1 2 2 2 0 NTPase DEAD PF00270.29 KKK13288.1 - 0.087 12.6 0.1 1.1 9.0 0.0 2.4 1 1 1 2 2 2 0 DEAD/DEAH box helicase Amidase PF01425.21 KKK13289.1 - 1.2e-97 327.7 0.0 2.1e-97 326.9 0.0 1.3 1 1 0 1 1 1 1 Amidase Thioesterase PF00975.20 KKK13289.1 - 0.083 13.0 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Fungal_trans PF04082.18 KKK13290.1 - 0.00012 21.2 1.3 0.00019 20.5 1.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain AA_permease_2 PF13520.6 KKK13291.1 - 3.9e-62 210.5 40.5 6e-62 209.8 40.5 1.3 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KKK13291.1 - 9.7e-27 93.7 23.0 9.7e-27 93.7 23.0 2.2 2 0 0 2 2 2 2 Amino acid permease NADHdeh_related PF10125.9 KKK13291.1 - 0.01 15.2 1.7 0.01 15.2 1.7 1.7 2 0 0 2 2 2 0 NADH dehydrogenase I, subunit N related protein Peptidase_M28 PF04389.17 KKK13306.1 - 2.7e-29 102.3 0.0 4.9e-29 101.5 0.0 1.3 1 1 0 1 1 1 1 Peptidase family M28 Sulf_transp PF04143.14 KKK13307.1 - 7.1e-07 29.1 0.3 7.1e-07 29.1 0.3 3.4 2 1 0 3 3 3 3 Sulphur transport RPN2_C PF18004.1 KKK13308.1 - 5.4e-57 192.2 8.9 9.6e-57 191.4 8.9 1.4 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN2 C-terminal domain PC_rep PF01851.22 KKK13308.1 - 1.1e-35 120.3 22.9 7.9e-10 38.7 0.1 8.4 8 0 0 8 8 8 6 Proteasome/cyclosome repeat HEAT_2 PF13646.6 KKK13308.1 - 5.7e-21 74.7 0.2 2.1e-14 53.6 0.0 4.2 3 1 2 5 5 5 4 HEAT repeats HEAT_EZ PF13513.6 KKK13308.1 - 4.4e-08 33.5 0.4 6.3e-05 23.4 0.1 4.8 4 1 1 5 5 5 2 HEAT-like repeat HEAT PF02985.22 KKK13308.1 - 3e-05 23.9 0.0 5.4 7.5 0.0 5.2 5 0 0 5 5 5 1 HEAT repeat Cnd1 PF12717.7 KKK13308.1 - 0.0041 17.2 0.6 0.26 11.3 0.0 3.1 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 CtsR_C PF17727.1 KKK13308.1 - 0.048 13.8 0.2 0.24 11.6 0.2 2.2 1 0 0 1 1 1 0 CtsR C-terminal dimerization domain HEAT_PBS PF03130.16 KKK13308.1 - 0.17 12.6 4.3 1.1 10.2 0.0 4.0 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat F-box-like PF12937.7 KKK13309.1 - 0.0054 16.6 3.0 0.015 15.2 0.5 2.7 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KKK13309.1 - 0.033 14.1 0.6 0.16 11.9 0.6 2.2 1 1 0 1 1 1 0 F-box domain p450 PF00067.22 KKK13310.1 - 0.00047 19.0 0.3 0.00097 18.0 0.3 1.5 1 0 0 1 1 1 1 Cytochrome P450 Seryl_tRNA_N PF02403.22 KKK13310.1 - 0.0064 16.7 12.3 0.068 13.4 4.5 3.0 1 1 0 2 2 2 2 Seryl-tRNA synthetase N-terminal domain V-SNARE PF05008.15 KKK13310.1 - 0.012 16.0 4.8 0.041 14.2 4.8 1.9 1 0 0 1 1 1 0 Vesicle transport v-SNARE protein N-terminus FlaC_arch PF05377.11 KKK13310.1 - 0.026 14.9 0.9 0.026 14.9 0.9 3.1 3 0 0 3 3 2 0 Flagella accessory protein C (FlaC) Paralemmin PF03285.15 KKK13310.1 - 0.052 13.1 7.6 0.04 13.5 6.1 1.5 1 1 0 1 1 1 0 Paralemmin COG5 PF10392.9 KKK13310.1 - 0.14 12.4 8.1 0.023 14.9 3.9 2.0 2 0 0 2 2 1 0 Golgi transport complex subunit 5 CLZ PF16526.5 KKK13310.1 - 0.14 12.5 6.9 0.12 12.7 2.7 2.7 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels ABATE PF07336.11 KKK13310.1 - 0.16 12.7 4.2 0.1 13.3 0.6 2.5 3 1 0 3 3 2 0 Putative stress-induced transcription regulator Spc24 PF08286.11 KKK13310.1 - 0.23 11.7 7.7 1.1 9.5 3.0 2.9 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 TPR_MLP1_2 PF07926.12 KKK13310.1 - 0.26 11.3 22.2 0.52 10.4 8.1 3.1 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein DUF1664 PF07889.12 KKK13310.1 - 0.67 10.0 6.3 0.53 10.3 2.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Laminin_II PF06009.12 KKK13310.1 - 1 9.4 8.7 0.8 9.7 3.0 2.7 3 0 0 3 3 3 0 Laminin Domain II DUF3450 PF11932.8 KKK13310.1 - 1.4 8.1 13.7 0.68 9.2 4.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Phage_GP20 PF06810.11 KKK13310.1 - 2.5 7.9 9.3 0.29 10.9 0.8 2.8 2 1 1 3 3 3 0 Phage minor structural protein GP20 DivIC PF04977.15 KKK13310.1 - 3.7 7.4 6.5 12 5.8 1.3 2.9 2 0 0 2 2 2 0 Septum formation initiator Allexi_40kDa PF05549.11 KKK13310.1 - 6 6.3 8.8 3.2 7.2 5.1 2.1 2 1 0 2 2 2 0 Allexivirus 40kDa protein Filament PF00038.21 KKK13310.1 - 6.3 6.3 24.4 0.067 12.8 8.0 3.1 3 1 1 4 4 4 0 Intermediate filament protein LMBR1 PF04791.16 KKK13310.1 - 6.7 5.5 5.6 9.1 5.1 5.6 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF724 PF05266.14 KKK13310.1 - 8.3 6.2 12.1 1.3 8.8 5.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF724) E2F_CC-MB PF16421.5 KKK13310.1 - 9.8 6.6 7.3 35 4.8 0.0 3.4 3 0 0 3 3 3 0 E2F transcription factor CC-MB domain PAXNEB PF05625.11 KKK13321.1 - 2.9e-117 392.0 0.0 3.3e-117 391.8 0.0 1.0 1 0 0 1 1 1 1 PAXNEB protein TMEM119 PF15724.5 KKK13321.1 - 0.4 10.7 5.4 0.46 10.5 2.7 2.0 2 0 0 2 2 2 0 TMEM119 family tRNA_int_endo PF01974.17 KKK13322.1 - 1.1e-14 54.2 0.0 2.2e-14 53.3 0.0 1.4 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain Autophagy_N PF03986.13 KKK13322.1 - 0.17 11.8 3.0 0.29 11.1 3.0 1.2 1 0 0 1 1 1 0 Autophagocytosis associated protein (Atg3), N-terminal domain DEAD PF00270.29 KKK13323.1 - 3.1e-42 144.3 0.0 4.8e-42 143.7 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KKK13323.1 - 1.5e-20 73.6 0.0 4.2e-20 72.2 0.0 1.9 1 1 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 KKK13323.1 - 7.1e-20 71.0 0.0 1.4e-19 70.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 KKK13323.1 - 1.8e-06 28.1 0.0 4.1e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KKK13323.1 - 0.0098 15.1 0.0 0.021 14.1 0.0 1.5 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase WD40 PF00400.32 KKK13324.1 - 4e-12 46.4 9.7 0.0087 16.9 0.1 7.1 8 0 0 8 8 8 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKK13324.1 - 0.0064 16.8 0.0 1.1 9.7 0.0 3.3 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Fungal_trans_2 PF11951.8 KKK13325.1 - 1.2e-09 37.4 2.7 3.1e-08 32.8 2.7 2.2 1 1 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 KKK13326.1 - 3.6e-27 95.2 24.1 3.6e-27 95.2 24.1 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily GATase PF00117.28 KKK13327.1 - 2.1e-12 47.2 0.0 2.9e-12 46.7 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 KKK13327.1 - 0.036 13.8 0.6 1.2 8.9 0.6 2.8 1 1 0 1 1 1 0 Peptidase C26 GATase_3 PF07685.14 KKK13327.1 - 0.15 11.6 0.0 0.27 10.8 0.0 1.4 1 1 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain DUF775 PF05603.12 KKK13328.1 - 9.1e-66 221.2 0.0 1e-65 221.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF775) NUDIX PF00293.28 KKK13329.1 - 8.5e-14 51.7 0.0 1.1e-13 51.3 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain RNA_pol_Rpb8 PF03870.15 KKK13330.1 - 1e-45 155.3 0.0 1.1e-45 155.2 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 RNA_pol_RpbG PF16992.5 KKK13330.1 - 0.0032 17.5 0.0 1 9.4 0.0 2.1 2 0 0 2 2 2 2 DNA-directed RNA polymerase, subunit G LRR_9 PF14580.6 KKK13331.1 - 4.8e-62 208.5 0.1 4.8e-62 208.5 0.1 1.5 2 0 0 2 2 2 1 Leucine-rich repeat LRR_8 PF13855.6 KKK13331.1 - 5.7e-05 22.8 1.6 0.00018 21.2 1.6 1.9 1 0 0 1 1 1 1 Leucine rich repeat LRR_4 PF12799.7 KKK13331.1 - 0.00066 20.0 4.9 0.24 11.9 0.1 3.2 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) DUF4349 PF14257.6 KKK13331.1 - 0.0058 16.1 1.4 0.011 15.2 1.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4349) Ribonuc_2-5A PF06479.12 KKK13332.1 - 1.9e-39 134.8 0.0 3.1e-39 134.0 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase PF00069.25 KKK13332.1 - 1.4e-32 113.1 0.0 2.7e-27 95.8 0.0 3.2 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KKK13332.1 - 1.4e-14 54.0 0.0 2.8e-12 46.5 0.0 2.9 1 1 0 2 2 2 1 Protein tyrosine kinase PQQ PF01011.21 KKK13332.1 - 1.8e-05 24.5 0.0 0.11 12.4 0.0 3.1 3 0 0 3 3 3 2 PQQ enzyme repeat PQQ_2 PF13360.6 KKK13332.1 - 0.0045 16.6 0.1 0.05 13.2 0.1 2.3 1 1 0 1 1 1 1 PQQ-like domain Pkinase_fungal PF17667.1 KKK13332.1 - 0.016 14.0 0.0 0.047 12.5 0.0 1.7 2 0 0 2 2 2 0 Fungal protein kinase Cofilin_ADF PF00241.20 KKK13333.1 - 3.5e-20 72.0 0.0 4.3e-20 71.7 0.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein DZR PF12773.7 KKK13334.1 - 0.21 11.6 31.6 11 6.1 14.3 3.9 2 2 0 2 2 2 0 Double zinc ribbon FYVE_2 PF02318.16 KKK13334.1 - 3 8.1 21.2 0.52 10.5 2.6 3.3 3 0 0 3 3 3 0 FYVE-type zinc finger Zn_ribbon_17 PF17120.5 KKK13334.1 - 4.6 6.9 33.2 0.081 12.6 7.2 3.2 3 0 0 3 3 3 0 Zinc-ribbon, C4HC2 type HypA PF01155.19 KKK13334.1 - 6.4 6.8 26.5 4 7.5 3.2 3.4 3 0 0 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA SNF2_N PF00176.23 KKK13335.1 - 2.3e-55 187.8 0.1 3.5e-55 187.1 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KKK13335.1 - 8e-14 51.9 0.0 5.6e-11 42.8 0.0 2.5 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.15 KKK13335.1 - 6.1e-09 36.1 0.0 1.5e-08 34.9 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 KKK13335.1 - 0.00089 18.5 0.0 0.0016 17.6 0.0 1.4 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ERCC3_RAD25_C PF16203.5 KKK13335.1 - 0.037 13.2 0.0 0.082 12.1 0.0 1.5 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase UPF0086 PF01868.16 KKK13336.1 - 4.9e-33 112.9 0.1 9.7e-33 111.9 0.1 1.5 2 0 0 2 2 2 1 Domain of unknown function UPF0086 Pantoate_ligase PF02569.15 KKK13337.1 - 5.5e-91 304.5 0.0 7.6e-91 304.0 0.0 1.2 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase Pyridox_oxase_2 PF12766.7 KKK13338.1 - 2.1e-24 86.0 0.0 4.4e-24 85.0 0.0 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Glyco_transf_34 PF05637.12 KKK13339.1 - 7.6e-14 52.0 0.0 3.6e-09 36.7 0.0 2.2 1 1 1 2 2 2 2 galactosyl transferase GMA12/MNN10 family DUF273 PF03314.14 KKK13339.1 - 0.032 13.8 0.0 0.05 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF273 Nucleotid_trans PF03407.16 KKK13339.1 - 0.18 11.7 0.0 0.27 11.2 0.0 1.2 1 0 0 1 1 1 0 Nucleotide-diphospho-sugar transferase p450 PF00067.22 KKK13340.1 - 1.7e-79 267.8 0.0 1.9e-79 267.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 KKK13341.1 - 8.5e-29 100.6 33.7 1.9e-17 63.2 26.8 2.5 2 1 1 3 3 3 2 Major Facilitator Superfamily Ammonium_transp PF00909.21 KKK13342.1 - 6.5e-107 357.7 23.2 8.3e-107 357.3 23.2 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family GDA1_CD39 PF01150.17 KKK13343.1 - 1.3e-109 366.7 0.0 1.8e-109 366.3 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Acyltransferase PF01553.21 KKK13344.1 - 1e-17 64.0 0.0 2e-17 63.1 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase RRM_occluded PF16842.5 KKK13406.1 - 0.00084 19.1 0.0 0.099 12.5 0.0 2.5 2 0 0 2 2 2 2 Occluded RNA-recognition motif LON_substr_bdg PF02190.16 KKK13407.1 - 3.4e-27 95.7 0.0 4.7e-27 95.2 0.0 1.2 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain zf-C3HC4_2 PF13923.6 KKK13407.1 - 8.7e-11 41.5 16.4 2e-10 40.4 9.2 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KKK13407.1 - 8.1e-10 38.6 19.5 2.7e-07 30.5 3.9 3.4 3 0 0 3 3 3 2 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KKK13407.1 - 1.1e-09 38.0 12.7 2.2e-08 33.8 4.9 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KKK13407.1 - 1.3e-09 37.9 14.8 1.4e-06 28.1 6.6 2.4 2 0 0 2 2 2 2 zinc-RING finger domain zf-RING_2 PF13639.6 KKK13407.1 - 1.3e-08 35.0 15.8 9.3e-07 29.1 7.9 2.6 2 0 0 2 2 2 2 Ring finger domain zf-C3HC4 PF00097.25 KKK13407.1 - 5.8e-08 32.5 13.3 3.8e-06 26.7 8.2 2.4 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KKK13407.1 - 3e-06 27.0 6.6 3e-06 27.0 6.6 2.4 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KKK13407.1 - 0.00021 21.4 8.8 0.00021 21.4 8.8 2.9 3 0 0 3 3 2 2 zinc finger of C3HC4-type, RING zf-P11 PF03854.14 KKK13407.1 - 0.0016 18.1 5.8 0.0016 18.1 5.8 2.0 2 0 0 2 2 2 1 P-11 zinc finger zf-RING_10 PF16685.5 KKK13407.1 - 0.0017 18.4 5.9 0.0017 18.4 5.9 2.3 2 0 0 2 2 2 1 zinc RING finger of MSL2 zf-rbx1 PF12678.7 KKK13407.1 - 0.0091 16.3 4.3 0.022 15.0 4.3 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_4 PF14570.6 KKK13407.1 - 0.012 15.4 6.1 0.049 13.4 4.4 2.5 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain U-box PF04564.15 KKK13407.1 - 0.031 14.5 0.0 0.072 13.3 0.0 1.6 1 0 0 1 1 1 0 U-box domain Ribosomal_L13 PF00572.18 KKK13408.1 - 3.7e-40 137.1 0.0 4.4e-40 136.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L13 Ribosomal_S9 PF00380.19 KKK13409.1 - 7.5e-28 97.5 0.1 8.4e-28 97.3 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Lipase_3 PF01764.25 KKK13410.1 - 1.1e-30 106.4 0.0 1.5e-30 105.9 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 KKK13410.1 - 0.00035 19.9 0.0 0.00057 19.2 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KKK13410.1 - 0.00042 21.0 1.8 0.00062 20.4 1.8 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 KKK13410.1 - 0.0018 18.0 0.0 0.0035 17.1 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Esterase PF00756.20 KKK13410.1 - 0.0037 17.0 0.0 0.0063 16.2 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Abhydrolase_1 PF00561.20 KKK13410.1 - 0.044 13.4 0.0 0.1 12.2 0.0 1.6 2 0 0 2 2 2 0 alpha/beta hydrolase fold Lipase PF00151.19 KKK13410.1 - 0.14 11.4 0.0 0.25 10.6 0.0 1.3 1 0 0 1 1 1 0 Lipase DUF2974 PF11187.8 KKK13410.1 - 0.15 11.6 0.1 0.91 9.0 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) DUF676 PF05057.14 KKK13410.1 - 0.18 11.3 0.0 0.26 10.7 0.0 1.1 1 0 0 1 1 1 0 Putative serine esterase (DUF676) HEAT_2 PF13646.6 KKK13423.1 - 0.0014 19.0 0.8 0.55 10.7 0.1 3.5 3 0 0 3 3 3 1 HEAT repeats RIH_assoc PF08454.11 KKK13423.1 - 0.049 13.5 0.1 0.99 9.3 0.0 2.9 2 0 0 2 2 2 0 RyR and IP3R Homology associated APC_u9 PF16633.5 KKK13423.1 - 0.11 13.6 0.0 0.5 11.5 0.0 2.1 1 0 0 1 1 1 0 Unstructured region on APC between 1st two creatine-rich regions Glyco_hydro_35 PF01301.19 KKK13423.1 - 0.13 11.8 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 35 HEAT_EZ PF13513.6 KKK13423.1 - 0.66 10.6 3.7 1.9 9.0 1.1 3.0 2 0 0 2 2 2 0 HEAT-like repeat HEAT PF02985.22 KKK13423.1 - 1.7 9.1 5.8 35 5.0 0.1 4.6 4 0 0 4 4 4 0 HEAT repeat eIF-5_eIF-2B PF01873.17 KKK13424.1 - 4e-39 133.1 0.0 8.3e-39 132.1 0.0 1.5 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.18 KKK13424.1 - 5e-22 77.8 0.3 1.4e-21 76.4 0.3 1.8 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon MCM PF00493.23 KKK13425.1 - 6.5e-102 339.4 0.0 9.7e-102 338.8 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain VTC PF09359.10 KKK13425.1 - 3.2e-98 328.5 0.1 8e-98 327.2 0.0 1.8 2 0 0 2 2 2 1 VTC domain MCM_OB PF17207.3 KKK13425.1 - 2.6e-39 134.0 1.6 5.4e-39 132.9 1.6 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KKK13425.1 - 9.2e-29 99.7 3.8 9.6e-29 99.7 1.1 2.5 3 0 0 3 3 2 1 MCM AAA-lid domain MCM_N PF14551.6 KKK13425.1 - 2.9e-18 66.4 0.1 1.2e-17 64.3 0.1 2.2 1 0 0 1 1 1 1 MCM N-terminal domain DUF202 PF02656.15 KKK13425.1 - 2.5e-12 47.1 4.2 2.5e-12 47.1 4.2 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF202) SPX PF03105.19 KKK13425.1 - 8.6e-08 32.5 1.3 2.4e-05 24.4 0.0 5.3 4 2 1 5 5 4 3 SPX domain Mg_chelatase PF01078.21 KKK13425.1 - 1.5e-05 24.5 0.0 0.00027 20.4 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KKK13425.1 - 3.4e-05 23.9 0.0 9.3e-05 22.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 KKK13425.1 - 0.0019 18.0 0.0 0.0044 16.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF999 PF06198.11 KKK13425.1 - 1.4 8.9 4.5 20 5.2 0.5 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF999) DNA_ligase_A_M PF01068.21 KKK13426.1 - 1.1e-52 178.6 0.9 1.5e-50 171.7 0.9 2.3 1 1 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 KKK13426.1 - 8.8e-45 153.1 0.0 2e-44 152.0 0.0 1.7 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 KKK13426.1 - 4.9e-27 94.4 0.0 1.4e-26 93.0 0.0 1.8 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 KKK13426.1 - 6e-05 23.4 0.1 0.00011 22.6 0.1 1.4 1 0 0 1 1 1 1 RNA ligase Synaptonemal_3 PF15191.6 KKK13426.1 - 0.11 12.2 0.0 0.37 10.6 0.0 1.9 1 0 0 1 1 1 0 Synaptonemal complex central element protein 3 CDC45 PF02724.14 KKK13426.1 - 9 4.4 11.7 16 3.6 11.7 1.3 1 0 0 1 1 1 0 CDC45-like protein Methyltransf_25 PF13649.6 KKK13427.1 - 0.0095 16.6 0.0 0.021 15.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ank_4 PF13637.6 KKK13427.1 - 0.017 15.7 0.0 2.5 8.8 0.0 2.5 2 0 0 2 2 2 0 Ankyrin repeats (many copies) DUF429 PF04250.13 KKK13427.1 - 0.018 14.8 0.8 0.45 10.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF429) Spt5_N PF11942.8 KKK13427.1 - 3.3 8.7 10.1 11 7.1 2.5 2.4 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal RSN1_7TM PF02714.15 KKK13428.1 - 3.8e-82 275.7 32.2 6.3e-82 275.0 32.2 1.4 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 KKK13428.1 - 2.7e-47 160.4 0.2 2.7e-47 160.4 0.2 3.5 4 1 0 4 4 4 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 KKK13428.1 - 1e-29 104.0 1.7 2.4e-18 67.0 0.1 2.7 3 0 0 3 3 3 2 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 KKK13428.1 - 3.3e-13 49.6 0.0 8.6e-13 48.3 0.0 1.7 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter DUF676 PF05057.14 KKK13429.1 - 6.1e-06 25.9 0.0 4.8e-05 23.0 0.0 2.1 2 0 0 2 2 2 1 Putative serine esterase (DUF676) Hydrolase_4 PF12146.8 KKK13429.1 - 0.00061 19.1 0.0 0.0011 18.3 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KKK13429.1 - 0.015 15.9 0.2 0.048 14.2 0.0 2.0 2 0 0 2 2 2 0 Alpha/beta hydrolase family Abhydrolase_8 PF06259.12 KKK13429.1 - 0.094 12.3 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase PGAP1 PF07819.13 KKK13429.1 - 0.12 12.1 0.0 0.47 10.1 0.0 1.8 1 1 0 1 1 1 0 PGAP1-like protein Cpn60_TCP1 PF00118.24 KKK13431.1 - 1.5e-86 291.0 9.2 3.2e-86 289.9 9.2 1.5 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family SnoaL_4 PF13577.6 KKK13431.1 - 0.27 11.4 0.6 2 8.5 0.2 2.5 2 1 1 3 3 3 0 SnoaL-like domain Chlorosome_CsmC PF11098.8 KKK13431.1 - 0.6 10.1 8.3 6.2 6.8 0.1 3.8 4 0 0 4 4 4 0 Chlorosome envelope protein C HA2 PF04408.23 KKK13434.1 - 5.1e-22 78.2 0.2 1.8e-21 76.5 0.2 2.0 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KKK13434.1 - 1.6e-13 50.8 0.0 3.4e-13 49.8 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KKK13434.1 - 2.8e-11 43.7 0.0 6.8e-11 42.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 KKK13434.1 - 0.00017 21.9 0.0 0.00043 20.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 KKK13434.1 - 0.0034 17.1 0.0 0.014 15.2 0.0 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain DEAD PF00270.29 KKK13434.1 - 0.0047 16.7 0.0 0.012 15.3 0.0 1.6 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.6 KKK13434.1 - 0.01 16.2 0.0 0.027 14.8 0.0 1.7 1 1 0 1 1 1 0 AAA domain CLP1_P PF16575.5 KKK13434.1 - 0.018 14.9 0.0 0.04 13.7 0.0 1.6 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop ABC_tran PF00005.27 KKK13434.1 - 0.034 14.7 0.0 0.12 12.9 0.0 1.9 1 0 0 1 1 1 0 ABC transporter SPATA1_C PF15743.5 KKK13434.1 - 0.036 14.1 1.4 0.092 12.8 1.4 1.6 1 0 0 1 1 1 0 Spermatogenesis-associated C-terminus ATPase PF06745.13 KKK13434.1 - 0.041 13.2 0.0 0.086 12.2 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_25 PF13481.6 KKK13434.1 - 0.096 12.3 0.0 0.43 10.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain F-box-like PF12937.7 KKK13435.1 - 3.5e-08 33.2 0.1 7.1e-08 32.2 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KKK13435.1 - 4.1e-06 26.5 0.1 1.1e-05 25.2 0.1 1.7 1 0 0 1 1 1 1 F-box domain MIT PF04212.18 KKK13435.1 - 0.042 13.9 0.7 0.087 12.9 0.7 1.4 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain TPR_2 PF07719.17 KKK13435.1 - 0.12 12.6 0.7 1.3 9.3 0.9 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat Mito_carr PF00153.27 KKK13436.1 - 1.3e-63 210.9 0.9 9.7e-20 70.3 0.0 4.2 3 1 1 4 4 4 4 Mitochondrial carrier protein Serine_protease PF18405.1 KKK13436.1 - 0.19 10.8 2.6 0.26 10.4 0.0 2.3 3 0 0 3 3 3 0 Gammaproteobacterial serine protease ATP-synt_Eps PF04627.13 KKK13437.1 - 1.6e-23 82.4 1.0 2.2e-23 82.0 1.0 1.2 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain Mak10 PF04112.13 KKK13438.1 - 1.1e-64 216.9 0.1 2.3e-64 215.9 0.1 1.5 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase Zn_clus PF00172.18 KKK13438.1 - 3.6e-09 36.6 9.3 3.6e-09 36.6 9.3 2.2 1 1 1 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KKK13438.1 - 2.4e-07 30.0 0.0 5e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Ribosomal_L7Ae PF01248.26 KKK13439.1 - 3.3e-24 84.4 0.0 3.7e-24 84.3 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Ribosomal_L16 PF00252.18 KKK13440.1 - 5.6e-44 149.3 0.1 7e-44 149.0 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Lyase_aromatic PF00221.19 KKK13441.1 - 7.2e-152 506.3 4.2 9.9e-152 505.8 4.2 1.0 1 0 0 1 1 1 1 Aromatic amino acid lyase SNF2_N PF00176.23 KKK13442.1 - 6.3e-19 67.9 0.8 7.4e-12 44.6 0.0 2.4 2 0 0 2 2 2 2 SNF2 family N-terminal domain DNA_methylase PF00145.17 KKK13442.1 - 1.9e-17 63.6 0.0 4.1e-17 62.5 0.0 1.6 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase Helicase_C PF00271.31 KKK13442.1 - 3.1e-06 27.5 0.0 8.8e-06 26.0 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Prok-RING_4 PF14447.6 KKK13442.1 - 0.0048 16.7 4.3 0.0048 16.7 4.3 2.5 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 KKK13442.1 - 0.2 11.5 9.4 0.9 9.4 2.2 2.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) IBR PF01485.21 KKK13442.1 - 0.22 11.8 9.4 1.1 9.5 3.1 2.8 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain zf-RING_5 PF14634.6 KKK13442.1 - 0.45 10.5 24.2 0.0081 16.1 6.5 2.9 3 0 0 3 3 3 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 KKK13442.1 - 0.87 9.7 11.6 0.83 9.7 2.9 2.7 2 0 0 2 2 2 0 RING-type zinc-finger Band_7 PF01145.25 KKK13443.1 - 1.7e-23 83.5 2.9 2.5e-23 83.0 2.9 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family CSTF2_hinge PF14327.6 KKK13444.1 - 4.8e-33 113.4 2.2 4.8e-33 113.4 2.2 2.2 3 0 0 3 3 3 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.22 KKK13444.1 - 1.4e-19 69.7 0.0 2.2e-19 69.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.6 KKK13444.1 - 3.8e-16 58.4 13.0 3.8e-16 58.4 13.0 3.2 2 1 1 3 3 3 1 Transcription termination and cleavage factor C-terminal RRM_7 PF16367.5 KKK13444.1 - 0.009 16.1 0.1 0.78 9.9 0.0 2.5 1 1 1 2 2 2 1 RNA recognition motif RRM_occluded PF16842.5 KKK13444.1 - 0.014 15.2 0.0 0.04 13.8 0.0 1.7 1 1 0 1 1 1 0 Occluded RNA-recognition motif Spo7_2_N PF15407.6 KKK13444.1 - 0.03 14.0 0.0 0.056 13.1 0.0 1.4 1 0 0 1 1 1 0 Sporulation protein family 7 RRM_Rrp7 PF17799.1 KKK13444.1 - 0.057 13.2 0.0 5.3 6.8 0.0 2.2 1 1 1 2 2 2 0 Rrp7 RRM-like N-terminal domain Sua5_yciO_yrdC PF01300.18 KKK13445.1 - 2e-54 183.8 0.0 4.4e-54 182.7 0.0 1.6 1 0 0 1 1 1 1 Telomere recombination NFACT-C PF11923.8 KKK13445.1 - 1.7e-40 137.2 0.2 1.7e-40 137.2 0.2 3.6 4 0 0 4 4 4 1 NFACT protein C-terminal domain SUA5 PF03481.13 KKK13445.1 - 9.2e-32 110.4 0.0 9.2e-32 110.4 0.0 3.5 5 0 0 5 5 5 1 Putative GTP-binding controlling metal-binding NFACT-R_1 PF05670.13 KKK13445.1 - 3.7e-27 95.1 0.0 1.6e-26 93.1 0.0 2.1 2 0 0 2 2 2 1 NFACT protein RNA binding domain FbpA PF05833.11 KKK13445.1 - 6.5e-18 64.7 13.3 1.9e-12 46.7 0.1 3.8 3 1 1 4 4 4 2 Fibronectin-binding protein A N-terminus (FbpA) Clat_adaptor_s PF01217.20 KKK13445.1 - 5.2e-10 39.4 0.0 2.2e-08 34.2 0.1 2.8 3 0 0 3 3 3 1 Clathrin adaptor complex small chain PIG-L PF02585.17 KKK13445.1 - 0.92 10.1 3.1 2.6 8.7 0.0 2.8 2 0 0 2 2 2 0 GlcNAc-PI de-N-acetylase 2Fe-2S_thioredx PF01257.19 KKK13447.1 - 6e-60 201.3 0.0 7.9e-60 200.9 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin A_deaminase PF00962.22 KKK13448.1 - 2.2e-82 277.1 0.0 2.5e-82 276.9 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase SR-25 PF10500.9 KKK13449.1 - 0.12 12.0 2.6 0.17 11.5 2.6 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Cytomega_TRL10 PF06084.11 KKK13449.1 - 2.3 8.2 6.9 0.69 9.9 2.8 2.1 2 0 0 2 2 2 0 Cytomegalovirus TRL10 protein TrkH PF02386.16 KKK13450.1 - 2.2e-118 395.9 4.2 3.7e-118 395.1 1.3 1.9 2 0 0 2 2 2 1 Cation transport protein HemY_N PF07219.13 KKK13450.1 - 0.07 13.3 4.2 0.68 10.2 0.2 3.2 2 0 0 2 2 2 0 HemY protein N-terminus SelP_N PF04592.14 KKK13450.1 - 0.55 9.6 7.0 0.87 8.9 7.0 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Metallophos_C PF14008.6 KKK13451.1 - 8.4e-20 71.4 1.2 1.3e-18 67.6 0.3 2.7 2 0 0 2 2 2 1 Iron/zinc purple acid phosphatase-like protein C Metallophos PF00149.28 KKK13451.1 - 8.4e-13 49.3 0.5 1.6e-12 48.4 0.1 1.6 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Pur_ac_phosph_N PF16656.5 KKK13451.1 - 1.2e-06 29.0 0.2 0.00069 20.1 0.0 2.5 1 1 1 2 2 2 2 Purple acid Phosphatase, N-terminal domain TPMT PF05724.11 KKK13452.1 - 7.7e-28 97.6 0.0 1.7e-27 96.6 0.0 1.6 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_23 PF13489.6 KKK13452.1 - 7.1e-08 32.5 0.0 9.3e-08 32.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KKK13452.1 - 1.3e-05 25.8 0.0 4.1e-05 24.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKK13452.1 - 2e-05 25.2 0.0 0.00021 22.0 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KKK13452.1 - 3.5e-05 23.7 0.0 0.13 12.0 0.0 2.1 2 0 0 2 2 2 2 Methyltransferase domain VbhA PF18495.1 KKK13452.1 - 0.0084 16.0 0.1 0.017 15.0 0.1 1.4 1 0 0 1 1 1 1 Antitoxin VbhA Methyltransf_12 PF08242.12 KKK13452.1 - 0.025 15.3 0.0 0.077 13.7 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain N2227 PF07942.12 KKK13452.1 - 0.03 13.5 0.0 0.043 13.0 0.0 1.1 1 0 0 1 1 1 0 N2227-like protein MetW PF07021.12 KKK13452.1 - 0.2 11.2 0.0 0.3 10.7 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW adh_short_C2 PF13561.6 KKK13453.1 - 3.1e-46 157.8 0.0 1.2e-45 155.9 0.0 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KKK13453.1 - 2.2e-34 118.6 0.0 1e-33 116.5 0.0 1.8 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KKK13453.1 - 6.3e-11 42.5 0.1 1.5e-09 38.0 0.0 2.6 2 1 0 2 2 2 1 KR domain 3Beta_HSD PF01073.19 KKK13453.1 - 0.041 12.9 0.0 0.083 11.9 0.0 1.6 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_7 PF13241.6 KKK13453.1 - 0.046 14.2 0.0 0.17 12.3 0.0 2.0 2 1 0 2 2 2 0 Putative NAD(P)-binding Epimerase PF01370.21 KKK13453.1 - 0.096 12.1 0.0 0.37 10.2 0.0 1.9 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Peptidase_M14 PF00246.24 KKK13455.1 - 1.2e-74 251.7 0.0 1.6e-74 251.4 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase AA_permease PF00324.21 KKK13456.1 - 2.4e-116 389.2 40.3 4e-115 385.2 40.3 1.9 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KKK13456.1 - 6.2e-30 104.4 39.3 3.3e-29 102.0 39.2 2.0 1 1 0 1 1 1 1 Amino acid permease DUF3098 PF11297.8 KKK13456.1 - 0.039 13.5 0.2 0.039 13.5 0.2 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3098) Dcc1 PF09724.9 KKK13457.1 - 0.021 14.1 0.0 0.035 13.4 0.0 1.3 1 1 0 1 1 1 0 Sister chromatid cohesion protein Dcc1 NicO PF03824.16 KKK13458.1 - 4.2e-62 210.1 11.5 6.3e-59 199.6 4.5 2.7 2 1 1 3 3 3 2 High-affinity nickel-transport protein DNA_pol_B_thumb PF14791.6 KKK13459.1 - 1.5e-20 73.1 2.9 2.3e-20 72.5 0.2 2.3 2 0 0 2 2 2 1 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.9 KKK13459.1 - 9.5e-16 57.4 0.1 1.8e-15 56.5 0.1 1.5 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda DNA_pol_B_palm PF14792.6 KKK13459.1 - 3e-15 56.4 1.2 1.9e-14 53.8 1.2 2.3 1 1 0 1 1 1 1 DNA polymerase beta palm HHH_8 PF14716.6 KKK13459.1 - 1.3e-10 41.5 0.0 1.8e-09 37.8 0.1 2.3 2 0 0 2 2 2 1 Helix-hairpin-helix domain NTP_transf_2 PF01909.23 KKK13459.1 - 0.011 16.0 0.1 0.048 14.0 0.1 2.1 1 1 0 1 1 1 0 Nucleotidyltransferase domain BRCT_2 PF16589.5 KKK13459.1 - 0.062 13.7 0.0 0.14 12.6 0.0 1.6 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain HHH_5 PF14520.6 KKK13459.1 - 0.12 12.9 0.0 0.31 11.7 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix domain IMS_HHH PF11798.8 KKK13459.1 - 0.17 12.3 0.0 0.54 10.7 0.0 1.8 1 0 0 1 1 1 0 IMS family HHH motif Ribosomal_L7Ae PF01248.26 KKK13460.1 - 2e-19 69.1 1.1 1.7e-18 66.1 1.1 2.3 1 1 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family 2-Hacid_dh_C PF02826.19 KKK13463.1 - 5e-41 140.0 0.0 6.8e-41 139.6 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KKK13463.1 - 8e-06 25.6 0.0 1.1e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain F420_oxidored PF03807.17 KKK13463.1 - 0.00019 21.9 0.3 0.00057 20.4 0.0 1.9 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 KKK13463.1 - 0.0022 18.2 0.4 0.0037 17.4 0.1 1.5 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 KKK13463.1 - 0.0028 17.2 0.0 0.0046 16.5 0.0 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain 3HCDH_N PF02737.18 KKK13463.1 - 0.0051 16.7 0.0 0.0093 15.9 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain XdhC_C PF13478.6 KKK13463.1 - 0.021 15.3 0.0 0.036 14.6 0.0 1.3 1 0 0 1 1 1 0 XdhC Rossmann domain AlaDh_PNT_C PF01262.21 KKK13463.1 - 0.037 13.3 0.1 0.12 11.7 0.1 1.8 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain OPT PF03169.15 KKK13464.1 - 4.7e-174 580.4 17.2 5.4e-174 580.2 17.2 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein SH3_9 PF14604.6 KKK13465.1 - 4e-10 39.4 0.0 6.3e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KKK13465.1 - 2.3e-07 30.3 0.0 4.1e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KKK13465.1 - 2.5e-06 27.0 0.0 5.9e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain DUF4064 PF13273.6 KKK13465.1 - 0.0076 16.5 0.5 0.016 15.5 0.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF4064) Peptidase_M56 PF05569.11 KKK13465.1 - 0.045 13.0 0.3 0.071 12.3 0.1 1.4 1 1 0 1 1 1 0 BlaR1 peptidase M56 Amnionless PF14828.6 KKK13465.1 - 0.052 12.4 0.3 0.069 12.0 0.3 1.1 1 0 0 1 1 1 0 Amnionless Melittin PF01372.17 KKK13465.1 - 0.095 12.7 0.4 0.24 11.4 0.4 1.7 1 0 0 1 1 1 0 Melittin Stevor PF17410.2 KKK13465.1 - 0.11 12.0 0.5 0.18 11.3 0.5 1.3 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame DUF3042 PF11240.8 KKK13465.1 - 0.25 11.4 2.8 2.1 8.5 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3042) DUF4448 PF14610.6 KKK13465.1 - 0.36 10.6 8.5 0.016 15.0 2.0 2.0 3 0 0 3 3 3 0 Protein of unknown function (DUF4448) Macoilin PF09726.9 KKK13465.1 - 0.76 8.3 5.7 1.1 7.8 5.7 1.1 1 0 0 1 1 1 0 Macoilin family RIFIN PF02009.16 KKK13465.1 - 7.4 6.4 9.9 23 4.8 10.1 1.5 1 1 0 1 1 1 0 Rifin Pkinase PF00069.25 KKK13466.1 - 4.5e-43 147.5 0.0 6.2e-43 147.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK13466.1 - 1.5e-16 60.5 0.0 2.2e-16 59.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase KIX_2 PF16987.5 KKK13466.1 - 0.00037 20.4 0.8 0.00064 19.7 0.8 1.4 1 0 0 1 1 1 1 KIX domain KIX PF02172.16 KKK13466.1 - 0.0012 19.0 0.4 0.0024 18.1 0.4 1.4 1 0 0 1 1 1 1 KIX domain APH PF01636.23 KKK13466.1 - 0.0017 18.4 0.1 0.6 10.0 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KKK13466.1 - 0.0019 17.0 0.0 0.0065 15.3 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 KKK13466.1 - 0.0049 16.2 0.0 0.058 12.7 0.0 2.1 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 KKK13466.1 - 0.019 14.6 0.0 0.13 11.8 0.0 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 KKK13466.1 - 0.047 13.0 0.1 0.12 11.7 0.0 1.7 2 0 0 2 2 2 0 Kinase-like WPP PF13943.6 KKK13466.1 - 0.15 12.5 2.8 0.27 11.7 1.6 2.1 2 0 0 2 2 2 0 WPP domain muHD PF10291.9 KKK13467.1 - 2.4e-93 312.4 0.5 3.4e-93 311.9 0.5 1.2 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain FCH PF00611.23 KKK13467.1 - 1.5e-07 31.6 0.2 7.6e-07 29.3 0.0 2.3 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain Adap_comp_sub PF00928.21 KKK13467.1 - 0.032 13.6 0.1 0.16 11.3 0.1 2.1 1 1 0 1 1 1 0 Adaptor complexes medium subunit family ALMS_repeat PF18727.1 KKK13467.1 - 0.072 13.0 0.6 0.22 11.4 0.6 1.8 1 0 0 1 1 1 0 Alstrom syndrome repeat MAD PF05557.13 KKK13468.1 - 1.2e-56 192.5 82.5 3.2e-48 164.6 83.5 2.0 2 0 0 2 2 2 2 Mitotic checkpoint protein Methyltransf_34 PF11312.8 KKK13470.1 - 3e-103 345.3 0.0 7.1e-103 344.0 0.0 1.5 1 1 0 1 1 1 1 Putative SAM-dependent methyltransferase DUF5444 PF17519.2 KKK13470.1 - 0.12 12.4 0.0 0.52 10.3 0.0 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5444) FAM176 PF14851.6 KKK13470.1 - 3.8 7.2 5.8 0.6 9.8 0.3 2.1 2 0 0 2 2 2 0 FAM176 family Band_7 PF01145.25 KKK13471.1 - 1.4e-24 87.0 9.2 2e-24 86.6 8.2 1.7 1 1 0 1 1 1 1 SPFH domain / Band 7 family YdfA_immunity PF12127.8 KKK13471.1 - 0.0014 17.8 4.2 0.0018 17.4 4.2 1.2 1 0 0 1 1 1 1 SigmaW regulon antibacterial PknG_rubred PF16919.5 KKK13471.1 - 0.14 12.3 0.2 0.23 11.6 0.2 1.3 1 0 0 1 1 1 0 Protein kinase G rubredoxin domain SET PF00856.28 KKK13472.1 - 0.012 16.0 0.0 0.023 15.1 0.0 1.5 1 0 0 1 1 1 0 SET domain MMR_HSR1_C PF08438.10 KKK13474.1 - 4.1e-36 124.0 0.0 8.2e-36 123.0 0.0 1.5 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.23 KKK13474.1 - 6.4e-15 55.2 0.0 1.8e-14 53.8 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KKK13474.1 - 0.00059 19.4 0.1 0.0051 16.4 0.1 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 KKK13474.1 - 0.0071 16.4 1.4 0.3 11.1 0.5 2.6 3 0 0 3 3 3 1 Dynamin family GTP_EFTU PF00009.27 KKK13474.1 - 0.013 15.1 0.0 2.6 7.6 0.0 2.7 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain RHD3 PF05879.12 KKK13474.1 - 0.034 12.3 0.6 0.31 9.1 0.0 2.0 2 0 0 2 2 2 0 Root hair defective 3 GTP-binding protein (RHD3) ABC_tran PF00005.27 KKK13474.1 - 0.051 14.1 0.0 0.36 11.3 0.0 2.1 2 0 0 2 2 2 0 ABC transporter AAA_33 PF13671.6 KKK13474.1 - 0.087 13.0 0.1 9.2 6.4 0.2 2.3 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 KKK13474.1 - 0.096 13.1 0.0 0.39 11.1 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain Ploopntkinase3 PF18751.1 KKK13474.1 - 0.13 12.2 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 KTI12 PF08433.10 KKK13474.1 - 0.14 11.6 0.1 0.3 10.5 0.1 1.5 1 0 0 1 1 1 0 Chromatin associated protein KTI12 UcrQ PF02939.16 KKK13476.1 - 1.2e-33 114.9 0.1 1.4e-33 114.7 0.1 1.1 1 0 0 1 1 1 1 UcrQ family Cyt_b-c1_8 PF10890.8 KKK13476.1 - 0.065 13.6 0.0 0.11 12.9 0.0 1.4 1 1 0 1 1 1 0 Cytochrome b-c1 complex subunit 8 Spermine_synth PF01564.17 KKK13477.1 - 7.3e-73 244.0 0.0 9.8e-73 243.6 0.0 1.1 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 KKK13477.1 - 7.4e-24 83.4 0.1 1.2e-23 82.7 0.1 1.4 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Methyltransf_25 PF13649.6 KKK13477.1 - 5.6e-05 23.8 0.0 0.00013 22.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KKK13477.1 - 0.0006 20.5 0.1 0.014 16.2 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.7 KKK13477.1 - 0.012 15.5 0.0 0.022 14.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_24 PF13578.6 KKK13477.1 - 0.059 14.4 0.0 0.13 13.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Transketolase_N PF00456.21 KKK13478.1 - 1.6e-136 454.7 1.0 8.4e-70 235.3 0.1 2.2 1 1 1 2 2 2 2 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 KKK13478.1 - 2.9e-44 150.9 0.0 5e-44 150.1 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KKK13478.1 - 5.9e-12 45.6 0.0 1.6e-11 44.2 0.0 1.8 1 0 0 1 1 1 1 Transketolase, C-terminal domain GtrA PF04138.14 KKK13478.1 - 0.093 13.0 0.0 0.21 11.8 0.0 1.6 1 0 0 1 1 1 0 GtrA-like protein DXP_synthase_N PF13292.6 KKK13478.1 - 0.13 11.4 0.1 0.58 9.3 0.1 1.8 1 1 1 2 2 2 0 1-deoxy-D-xylulose-5-phosphate synthase Fungal_trans PF04082.18 KKK13479.1 - 7.8e-40 136.6 0.1 1.5e-39 135.6 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK13479.1 - 2e-08 34.2 14.9 3.4e-08 33.5 14.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Trimer_CC PF08954.11 KKK13479.1 - 0.13 11.9 0.6 0.37 10.4 0.6 1.8 1 0 0 1 1 1 0 Trimerisation motif DUF4635 PF15466.6 KKK13479.1 - 0.15 11.5 2.2 0.25 10.9 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4635) Cep57_MT_bd PF06657.13 KKK13479.1 - 0.18 12.3 2.5 13 6.3 0.2 2.6 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Tyrosinase PF00264.20 KKK13480.1 - 6e-56 190.2 0.1 9.6e-56 189.5 0.1 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase Abhydrolase_1 PF00561.20 KKK13481.1 - 2e-11 44.1 0.2 8e-10 38.8 0.1 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KKK13481.1 - 7.5e-11 43.0 4.3 1e-10 42.6 4.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KKK13481.1 - 7.5e-06 25.4 0.0 1.4e-05 24.5 0.0 1.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 ADP_ribosyl_GH PF03747.14 KKK13482.1 - 1e-56 192.9 0.3 1.1e-56 192.7 0.3 1.0 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase RabGAP-TBC PF00566.18 KKK13484.1 - 3.4e-48 164.1 0.6 2.9e-47 161.1 0.0 2.5 3 0 0 3 3 3 1 Rab-GTPase-TBC domain BLOC1_2 PF10046.9 KKK13484.1 - 3.2 8.1 5.6 2.2 8.6 0.1 3.2 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DNA_topoisoIV PF00521.20 KKK13485.1 - 5.9e-136 453.7 0.1 1.1e-135 452.8 0.1 1.5 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 KKK13485.1 - 3.8e-53 179.1 4.6 1.3e-51 174.2 3.0 3.0 2 0 0 2 2 2 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 KKK13485.1 - 1.6e-25 89.6 0.3 4.5e-25 88.1 0.3 1.8 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 KKK13485.1 - 4e-16 59.5 0.1 1.1e-15 58.1 0.1 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 KKK13485.1 - 1.6e-07 31.5 0.0 7.4e-07 29.3 0.0 2.2 1 0 0 1 1 1 1 Toprim domain Nsp1_C PF05064.13 KKK13485.1 - 0.015 15.1 0.1 0.051 13.4 0.1 1.9 1 0 0 1 1 1 0 Nsp1-like C-terminal region AT_hook PF02178.19 KKK13485.1 - 0.12 12.3 2.2 0.52 10.4 2.2 2.2 1 0 0 1 1 1 0 AT hook motif Patatin PF01734.22 KKK13486.1 - 1.9e-12 47.8 0.0 5.4e-12 46.3 0.0 1.8 1 1 0 1 1 1 1 Patatin-like phospholipase Fungal_trans PF04082.18 KKK13487.1 - 7e-11 41.7 0.8 1.2e-10 40.9 0.8 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK13487.1 - 3.6e-09 36.6 9.1 6.8e-09 35.7 9.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cutinase PF01083.22 KKK13488.1 - 1.5e-49 168.4 7.3 1.7e-49 168.2 7.3 1.0 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 KKK13488.1 - 0.0002 21.0 2.1 0.00076 19.1 0.2 2.0 1 1 1 2 2 2 1 PE-PPE domain Abhydrolase_6 PF12697.7 KKK13488.1 - 0.013 16.1 0.3 0.015 15.9 0.3 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase family Reticulon PF02453.17 KKK13491.1 - 8.8e-28 97.2 4.9 1.1e-27 96.9 4.9 1.1 1 0 0 1 1 1 1 Reticulon Cytochrome-c551 PF10643.9 KKK13491.1 - 0.052 13.1 0.1 0.075 12.6 0.1 1.2 1 0 0 1 1 1 0 Photosystem P840 reaction-centre cytochrome c-551 INCENP_ARK-bind PF03941.15 KKK13492.1 - 9.5e-15 54.3 0.7 9.5e-15 54.3 0.7 2.9 2 0 0 2 2 2 1 Inner centromere protein, ARK binding region Pkinase PF00069.25 KKK13493.1 - 0.033 13.5 0.0 0.063 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein kinase domain APH PF01636.23 KKK13493.1 - 0.32 10.9 0.0 0.32 10.9 0.0 1.9 3 0 0 3 3 3 0 Phosphotransferase enzyme family FA_hydroxylase PF04116.13 KKK13495.1 - 7.1e-25 87.9 15.8 7.1e-25 87.9 15.8 2.2 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily bVLRF1 PF18826.1 KKK13495.1 - 0.16 11.8 0.1 0.28 11.0 0.1 1.3 1 0 0 1 1 1 0 bacteroidetes VLRF1 release factor Ribosomal_L37ae PF01780.19 KKK13503.1 - 3.3e-41 139.2 10.2 3.7e-41 139.1 10.2 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family zf-RING_13 PF17977.1 KKK13503.1 - 0.0014 18.7 1.9 0.002 18.2 1.9 1.2 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Zn_Tnp_IS1595 PF12760.7 KKK13503.1 - 0.0064 16.4 2.9 0.011 15.7 2.9 1.4 1 0 0 1 1 1 1 Transposase zinc-ribbon domain A2L_zn_ribbon PF08792.10 KKK13503.1 - 0.017 14.8 3.1 0.51 10.1 0.1 2.2 2 0 0 2 2 2 0 A2L zinc ribbon domain DUF1451 PF07295.11 KKK13503.1 - 0.023 14.7 0.9 0.031 14.3 0.9 1.2 1 0 0 1 1 1 0 Zinc-ribbon containing domain Zn-ribbon_8 PF09723.10 KKK13503.1 - 0.078 13.1 0.6 0.16 12.1 0.6 1.5 1 0 0 1 1 1 0 Zinc ribbon domain zf-BED PF02892.15 KKK13503.1 - 0.13 12.3 4.6 1.4 9.0 0.4 2.2 1 1 1 2 2 2 0 BED zinc finger CarbpepA_inh PF02977.15 KKK13503.1 - 0.47 10.3 4.5 0.46 10.3 0.4 2.1 1 1 1 2 2 2 0 Carboxypeptidase A inhibitor zf-H2C2_2 PF13465.6 KKK13503.1 - 1.2 9.7 5.3 3.1 8.4 0.6 2.3 1 1 1 2 2 2 0 Zinc-finger double domain Pinin_SDK_memA PF04696.13 KKK13504.1 - 1.3e-30 106.1 12.4 1.3e-30 106.1 12.4 2.6 3 0 0 3 3 3 1 pinin/SDK/memA/ protein conserved region SR-25 PF10500.9 KKK13504.1 - 1.6 8.3 23.9 0.09 12.4 15.2 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Abhydrolase_1 PF00561.20 KKK13505.1 - 5.4e-21 75.4 0.2 7e-20 71.7 0.2 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KKK13505.1 - 5.5e-16 59.8 0.0 7.8e-16 59.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KKK13505.1 - 3.7e-10 39.5 0.0 3.5e-09 36.3 0.0 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Ndr PF03096.14 KKK13505.1 - 0.029 13.1 0.0 0.042 12.5 0.0 1.2 1 0 0 1 1 1 0 Ndr family MRP-L46 PF11788.8 KKK13505.1 - 0.17 12.7 0.0 0.29 11.9 0.0 1.4 1 0 0 1 1 1 0 39S mitochondrial ribosomal protein L46 Sacchrp_dh_NADP PF03435.18 KKK13506.1 - 2.8e-15 56.7 0.0 4.4e-15 56.1 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Cofilin_ADF PF00241.20 KKK13507.1 - 8.9e-29 99.7 0.0 1e-17 64.1 0.0 2.1 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein MFS_1 PF07690.16 KKK13508.1 - 6.4e-39 133.9 37.9 6.4e-39 133.9 37.9 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KKK13508.1 - 6.9e-11 41.7 9.6 6.9e-11 41.7 9.6 2.1 3 0 0 3 3 3 1 Sugar (and other) transporter PHD PF00628.29 KKK13509.1 - 1.5e-09 37.6 13.2 5.4e-09 35.8 5.8 2.6 2 0 0 2 2 2 1 PHD-finger zf-RING_2 PF13639.6 KKK13509.1 - 3.5e-09 36.8 0.7 3.5e-09 36.8 0.7 3.2 3 0 0 3 3 3 1 Ring finger domain zf-rbx1 PF12678.7 KKK13509.1 - 6.9e-07 29.5 0.3 6.9e-07 29.5 0.3 2.6 2 0 0 2 2 2 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 KKK13509.1 - 1.2e-06 28.2 0.9 1.2e-06 28.2 0.9 2.5 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 KKK13509.1 - 3.8e-06 26.7 0.1 3.8e-06 26.7 0.1 2.8 4 0 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KKK13509.1 - 4.3e-06 26.5 1.5 4.3e-06 26.5 1.5 2.6 4 0 0 4 4 2 1 Zinc finger, C3HC4 type (RING finger) PHD_2 PF13831.6 KKK13509.1 - 1.6e-05 24.4 1.8 1.6e-05 24.4 1.8 1.7 2 0 0 2 2 1 1 PHD-finger zf-RING_5 PF14634.6 KKK13509.1 - 1.9e-05 24.5 0.3 1.9e-05 24.5 0.3 3.0 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KKK13509.1 - 4.8e-05 23.1 0.6 4.8e-05 23.1 0.6 3.2 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 KKK13509.1 - 0.0019 17.8 0.4 0.0019 17.8 0.4 2.4 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-RING_UBOX PF13445.6 KKK13509.1 - 0.0032 17.5 1.5 0.0032 17.5 1.5 3.2 3 1 1 4 4 3 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 KKK13509.1 - 0.0042 17.1 0.0 0.0042 17.1 0.0 1.8 2 0 0 2 2 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zinc_ribbon_16 PF17034.5 KKK13509.1 - 0.03 14.6 0.1 0.07 13.3 0.1 1.6 1 0 0 1 1 1 0 Zinc-ribbon like family Rtf2 PF04641.12 KKK13509.1 - 0.065 12.6 0.0 0.065 12.6 0.0 1.9 2 0 0 2 2 2 0 Rtf2 RING-finger zf-RING_4 PF14570.6 KKK13509.1 - 0.11 12.3 0.1 0.11 12.3 0.1 2.4 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_11 PF17123.5 KKK13509.1 - 0.3 10.9 0.0 0.3 10.9 0.0 3.5 4 0 0 4 4 4 0 RING-like zinc finger DZR PF12773.7 KKK13509.1 - 0.45 10.6 5.2 1e+02 3.0 5.2 2.9 1 1 0 1 1 1 0 Double zinc ribbon Prok-RING_1 PF14446.6 KKK13509.1 - 0.67 9.9 8.4 0.91 9.5 2.0 3.1 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 zf-C2HC_2 PF13913.6 KKK13509.1 - 1.3 9.1 4.9 0.88 9.5 0.5 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type RecR PF02132.15 KKK13509.1 - 1.3 8.7 7.6 3.5 7.3 1.2 3.3 3 0 0 3 3 3 0 RecR protein zf-RING_9 PF13901.6 KKK13509.1 - 5.2 7.0 7.9 8 6.4 0.3 2.5 2 1 0 2 2 2 0 Putative zinc-RING and/or ribbon Lectin_leg-like PF03388.13 KKK13510.1 - 1e-26 93.8 0.0 1.6e-26 93.1 0.0 1.2 1 0 0 1 1 1 1 Legume-like lectin family SesA PF17107.5 KKK13510.1 - 0.017 15.3 1.1 0.042 14.0 1.1 1.6 1 1 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases FAM196 PF15265.6 KKK13510.1 - 0.04 13.4 2.6 0.049 13.1 2.6 1.1 1 0 0 1 1 1 0 FAM196 family EMP24_GP25L PF01105.24 KKK13510.1 - 0.096 12.6 1.9 0.21 11.5 1.9 1.6 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD ABC_tran_CTD PF16326.5 KKK13510.1 - 0.12 12.7 1.0 0.43 10.9 1.0 1.9 1 1 0 1 1 1 0 ABC transporter C-terminal domain DUF3232 PF11554.8 KKK13510.1 - 0.13 12.7 0.1 0.23 11.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3232) YmgB PF10798.8 KKK13510.1 - 0.28 11.0 1.1 0.65 9.9 1.1 1.6 1 0 0 1 1 1 0 Biofilm development protein YmgB/AriR DUF4349 PF14257.6 KKK13510.1 - 0.49 9.8 9.0 12 5.3 9.0 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4349) PHD PF00628.29 KKK13511.1 - 1.3e-19 69.9 18.2 7.2e-12 45.0 6.8 2.5 2 0 0 2 2 2 2 PHD-finger PHD_2 PF13831.6 KKK13511.1 - 0.047 13.2 17.8 0.04 13.5 1.4 3.7 4 0 0 4 4 4 0 PHD-finger C1_1 PF00130.22 KKK13511.1 - 0.083 12.8 14.0 0.069 13.0 2.6 2.5 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-PHD-like PF15446.6 KKK13511.1 - 0.23 11.1 15.4 0.17 11.5 2.7 3.0 3 0 0 3 3 3 0 PHD/FYVE-zinc-finger like domain zf-RanBP PF00641.18 KKK13511.1 - 0.39 10.1 4.2 0.21 10.9 0.6 2.3 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others zf-HC5HC2H_2 PF13832.6 KKK13511.1 - 2.1 8.5 6.9 12 6.0 0.6 2.4 2 0 0 2 2 2 0 PHD-zinc-finger like domain Alg6_Alg8 PF03155.15 KKK13512.1 - 3.4e-172 573.8 28.0 4e-172 573.6 28.0 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family SNF5 PF04855.12 KKK13513.1 - 3.1e-66 223.6 0.3 1.9e-65 221.0 0.3 2.0 1 1 0 1 1 1 1 SNF5 / SMARCB1 / INI1 HEAT_2 PF13646.6 KKK13514.1 - 3.8e-07 30.4 7.7 0.008 16.5 0.3 5.3 4 1 1 5 5 5 2 HEAT repeats HEAT PF02985.22 KKK13514.1 - 7.4e-07 28.9 9.0 0.01 16.0 0.0 6.1 6 0 0 6 6 6 2 HEAT repeat Cnd1 PF12717.7 KKK13514.1 - 1.8e-06 28.1 1.2 0.96 9.5 0.0 5.4 4 2 2 6 6 6 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 KKK13514.1 - 0.0044 17.5 8.7 0.026 15.0 0.1 4.8 5 0 0 5 5 5 1 HEAT-like repeat RIX1 PF08167.12 KKK13514.1 - 0.0057 16.4 0.2 3.4 7.4 0.0 4.2 5 0 0 5 5 5 1 rRNA processing/ribosome biogenesis Nipped-B_C PF12830.7 KKK13514.1 - 0.012 15.6 0.3 0.14 12.1 0.1 2.9 3 1 0 3 3 3 0 Sister chromatid cohesion C-terminus CLASP_N PF12348.8 KKK13514.1 - 0.021 14.4 0.3 1.8 8.0 0.1 3.3 2 1 1 3 3 3 0 CLASP N terminal Cohesin_HEAT PF12765.7 KKK13514.1 - 0.036 14.4 2.6 1 9.7 0.0 4.0 4 0 0 4 4 4 0 HEAT repeat associated with sister chromatid cohesion Peptidase_M24 PF00557.24 KKK13515.1 - 4e-09 36.5 0.1 6.7e-09 35.7 0.1 1.4 1 1 0 1 1 1 1 Metallopeptidase family M24 Exo_endo_phos PF03372.23 KKK13516.1 - 0.00015 21.3 0.1 0.00054 19.5 0.1 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family HNH_2 PF13391.6 KKK13516.1 - 0.17 12.0 0.1 2.1 8.5 0.0 2.3 2 0 0 2 2 2 0 HNH endonuclease FAD_binding_3 PF01494.19 KKK13518.1 - 1.8e-17 63.7 0.1 1.7e-06 27.6 0.0 3.1 3 0 0 3 3 3 3 FAD binding domain NAD_binding_8 PF13450.6 KKK13518.1 - 0.00035 20.7 0.2 0.00084 19.5 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KKK13518.1 - 0.0019 17.5 1.1 0.0046 16.2 0.7 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KKK13518.1 - 0.0044 16.1 1.6 0.29 10.2 0.2 2.7 3 0 0 3 3 3 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 KKK13518.1 - 0.0053 15.9 0.1 0.0099 15.0 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KKK13518.1 - 0.0087 15.7 0.6 0.014 15.0 0.6 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KKK13518.1 - 0.04 13.1 1.5 0.072 12.3 0.2 2.1 2 1 1 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KKK13518.1 - 0.055 12.7 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.27 KKK13518.1 - 0.076 13.6 0.3 0.57 10.8 0.1 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Doppel PF11466.8 KKK13519.1 - 0.16 11.7 2.1 3.2 7.5 0.1 2.7 2 0 0 2 2 2 0 Prion-like protein Doppel COX15-CtaA PF02628.15 KKK13520.1 - 7.8e-115 383.4 3.7 9.4e-115 383.1 3.7 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein TetR_C_34 PF17929.1 KKK13520.1 - 0.18 11.9 1.6 6 7.0 0.1 3.1 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain zf-C3HC PF07967.13 KKK13521.1 - 1.3e-41 141.7 0.0 1.1e-38 132.2 0.0 2.3 2 0 0 2 2 2 2 C3HC zinc finger-like Rsm1 PF08600.10 KKK13521.1 - 3.2e-37 126.6 0.1 8.9e-34 115.5 0.0 2.6 2 0 0 2 2 2 2 Rsm1-like DM PF00751.18 KKK13521.1 - 0.14 12.0 0.1 10 6.1 0.0 2.3 2 0 0 2 2 2 0 DM DNA binding domain Pox_MCEL PF03291.16 KKK13522.1 - 3e-64 217.2 0.0 1.3e-42 146.1 0.0 3.2 2 1 0 2 2 2 2 mRNA capping enzyme Methyltransf_25 PF13649.6 KKK13522.1 - 1.6e-07 32.0 0.0 0.014 16.0 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 KKK13522.1 - 4.1e-07 30.7 0.0 4.7e-06 27.3 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KKK13522.1 - 2.4e-05 24.9 0.0 0.053 14.2 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 KKK13522.1 - 0.00022 21.1 0.0 0.022 14.5 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KKK13522.1 - 0.00026 20.8 0.0 0.00059 19.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 KKK13522.1 - 0.022 13.9 0.0 0.036 13.3 0.0 1.2 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family Ribosomal_60s PF00428.19 KKK13522.1 - 0.044 14.4 1.1 0.044 14.4 1.1 2.4 3 0 0 3 3 3 0 60s Acidic ribosomal protein p450 PF00067.22 KKK13523.1 - 4.4e-58 197.1 0.0 6.2e-58 196.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 polyprenyl_synt PF00348.17 KKK13523.1 - 4.8e-22 78.2 0.0 7.3e-22 77.7 0.0 1.3 1 0 0 1 1 1 1 Polyprenyl synthetase GST_N_3 PF13417.6 KKK13524.1 - 7.5e-09 35.9 0.0 1.6e-08 34.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KKK13524.1 - 2.4e-08 34.2 0.0 4e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KKK13524.1 - 0.0043 17.0 0.7 0.011 15.7 0.2 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Peptidase_M43 PF05572.13 KKK13539.1 - 7.3e-11 42.2 0.3 1.6e-10 41.1 0.3 1.5 1 1 0 1 1 1 1 Pregnancy-associated plasma protein-A Peptidase_M10 PF00413.24 KKK13539.1 - 0.026 14.4 0.0 0.033 14.0 0.0 1.2 1 0 0 1 1 1 0 Matrixin Reprolysin_3 PF13582.6 KKK13539.1 - 0.068 13.7 0.0 0.21 12.1 0.0 1.8 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 KKK13539.1 - 0.07 12.8 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 KKK13539.1 - 0.25 11.5 0.5 1.2 9.3 0.5 2.0 1 1 0 1 1 1 0 Metallo-peptidase family M12 Abhydrolase_6 PF12697.7 KKK13540.1 - 8.7e-15 55.9 0.0 1.2e-14 55.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KKK13540.1 - 1.3e-11 44.6 0.2 7.8e-11 42.1 0.0 2.0 1 1 1 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KKK13540.1 - 4.3e-11 42.5 0.0 5.4e-11 42.2 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_8 PF06259.12 KKK13540.1 - 0.00057 19.6 0.0 0.0012 18.5 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase Thioesterase PF00975.20 KKK13540.1 - 0.00097 19.3 0.1 0.0014 18.8 0.1 1.5 1 1 0 1 1 1 1 Thioesterase domain PGAP1 PF07819.13 KKK13540.1 - 0.012 15.4 0.0 0.019 14.7 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein DUF1993 PF09351.10 KKK13542.1 - 2.5e-53 180.5 0.0 2.7e-53 180.4 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) LdpA_C PF12617.8 KKK13542.1 - 0.15 11.7 0.0 0.22 11.1 0.0 1.2 1 0 0 1 1 1 0 Iron-Sulfur binding protein C terminal DAGAT PF03982.13 KKK13543.1 - 7.1e-52 176.2 0.1 1.1e-51 175.5 0.1 1.3 1 0 0 1 1 1 1 Diacylglycerol acyltransferase UDPGT PF00201.18 KKK13543.1 - 6.3e-10 38.4 0.0 8.9e-10 38.0 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 KKK13543.1 - 0.0078 16.2 0.0 0.014 15.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain p450 PF00067.22 KKK13544.1 - 2.8e-58 197.8 0.0 3.6e-58 197.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.18 KKK13545.1 - 3.5e-09 36.1 0.2 1e-08 34.6 0.2 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK13545.1 - 1.2e-08 34.9 11.1 2.5e-08 33.9 11.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RVT_1 PF00078.27 KKK13545.1 - 0.011 15.3 0.0 0.027 14.0 0.0 1.6 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4456 PF14644.6 KKK13545.1 - 0.084 12.6 0.9 4.9 6.8 0.8 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4456) DUF1690 PF07956.11 KKK13545.1 - 0.71 10.3 3.9 17 5.8 0.7 3.6 4 0 0 4 4 4 0 Protein of Unknown function (DUF1690) ELO PF01151.18 KKK13547.1 - 1.6e-59 201.4 19.6 2e-59 201.1 19.6 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family DHHC PF01529.20 KKK13547.1 - 8.9 6.4 16.5 3.2 7.9 0.2 3.1 2 1 1 3 3 3 0 DHHC palmitoyltransferase ABC_membrane PF00664.23 KKK13548.1 - 6e-93 311.5 32.4 5.5e-49 167.3 13.5 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KKK13548.1 - 1.2e-71 239.7 0.0 9.1e-36 123.4 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KKK13548.1 - 3.3e-14 52.8 0.0 5.1e-05 22.8 0.1 3.9 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 KKK13548.1 - 1.1e-08 34.3 2.3 0.00079 18.3 0.1 2.8 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_29 PF13555.6 KKK13548.1 - 4.5e-07 29.5 0.3 0.0029 17.3 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KKK13548.1 - 7.6e-07 29.2 0.1 0.034 14.0 0.0 3.3 3 0 0 3 3 3 2 RsgA GTPase AAA_16 PF13191.6 KKK13548.1 - 7.9e-07 29.6 1.7 0.014 15.8 0.0 3.3 2 1 0 2 2 2 2 AAA ATPase domain AAA_15 PF13175.6 KKK13548.1 - 1e-06 28.7 0.0 0.017 14.8 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 KKK13548.1 - 4.4e-05 23.8 1.3 0.2 11.9 0.1 3.9 2 2 0 2 2 2 2 AAA domain AAA_21 PF13304.6 KKK13548.1 - 0.00012 22.0 3.0 0.29 10.9 0.2 3.9 3 1 1 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 KKK13548.1 - 0.00019 21.6 4.7 0.44 10.8 0.4 4.4 3 2 0 3 3 3 2 Putative exonuclease SbcCD, C subunit AAA_28 PF13521.6 KKK13548.1 - 0.0007 19.9 0.1 0.13 12.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 KKK13548.1 - 0.00074 20.1 0.6 0.22 12.0 0.1 2.9 3 0 0 3 3 3 1 AAA domain SRP54 PF00448.22 KKK13548.1 - 0.0011 18.7 0.0 2.1 7.9 0.0 2.9 2 0 0 2 2 2 2 SRP54-type protein, GTPase domain AAA_33 PF13671.6 KKK13548.1 - 0.0022 18.2 0.0 2.5 8.2 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KKK13548.1 - 0.0035 16.9 4.1 0.44 10.1 0.0 3.9 4 0 0 4 4 4 1 AAA domain AAA_7 PF12775.7 KKK13548.1 - 0.005 16.4 0.0 2.5 7.6 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_30 PF13604.6 KKK13548.1 - 0.0061 16.3 5.8 0.51 10.0 0.3 3.9 4 1 0 4 4 3 1 AAA domain Rad17 PF03215.15 KKK13548.1 - 0.007 16.3 0.1 0.55 10.1 0.0 2.4 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_5 PF07728.14 KKK13548.1 - 0.0074 16.3 0.1 11 6.0 0.0 3.9 3 1 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 KKK13548.1 - 0.0081 16.7 0.6 4.9 7.7 0.2 2.9 2 1 1 3 3 3 1 AAA domain G-alpha PF00503.20 KKK13548.1 - 0.01 15.0 0.0 3 6.9 0.0 2.5 2 1 0 2 2 2 0 G-protein alpha subunit DUF87 PF01935.17 KKK13548.1 - 0.02 15.0 0.4 4.5 7.3 0.2 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain MMR_HSR1 PF01926.23 KKK13548.1 - 0.026 14.6 0.1 7.5 6.7 0.0 2.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase Zeta_toxin PF06414.12 KKK13548.1 - 0.028 13.7 0.0 5 6.4 0.0 2.6 2 0 0 2 2 2 0 Zeta toxin PRK PF00485.18 KKK13548.1 - 0.054 13.2 0.0 2.3 7.9 0.0 2.6 3 0 0 3 3 2 0 Phosphoribulokinase / Uridine kinase family RNA_helicase PF00910.22 KKK13548.1 - 0.069 13.5 0.1 12 6.3 0.0 2.9 2 0 0 2 2 2 0 RNA helicase Mg_chelatase PF01078.21 KKK13548.1 - 0.093 12.1 0.0 3.6 6.9 0.0 2.5 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI APS_kinase PF01583.20 KKK13548.1 - 0.1 12.5 0.0 5.6 6.8 0.0 2.8 2 0 0 2 2 2 0 Adenylylsulphate kinase ATP-grasp_3 PF02655.14 KKK13549.1 - 1.4e-08 35.0 0.0 4.1e-08 33.4 0.0 1.8 1 1 0 1 1 1 1 ATP-grasp domain Glyco_hydro_16 PF00722.21 KKK13551.1 - 1.7e-07 30.9 0.0 3.5e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 NIP_1 PF08995.10 KKK13551.1 - 0.011 16.1 0.3 0.02 15.2 0.3 1.5 1 0 0 1 1 1 0 Necrosis inducing protein-1 COesterase PF00135.28 KKK13552.1 - 8.3e-16 57.9 0.1 3e-15 56.1 0.1 1.7 1 1 0 1 1 1 1 Carboxylesterase family COesterase PF00135.28 KKK13553.1 - 3.3e-35 122.0 0.0 4.6e-35 121.5 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KKK13553.1 - 0.00026 20.9 0.0 0.00047 20.1 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Clr5 PF14420.6 KKK13554.1 - 1e-12 48.0 1.2 1.7e-12 47.4 1.2 1.3 1 0 0 1 1 1 1 Clr5 domain THOC7 PF05615.13 KKK13554.1 - 0.15 12.3 0.9 0.58 10.4 0.4 2.0 1 1 1 2 2 2 0 Tho complex subunit 7 Glyco_hydro_7 PF00840.20 KKK13555.1 - 1.7e-127 425.8 17.1 1.7e-127 425.8 17.1 2.4 2 1 0 2 2 2 1 Glycosyl hydrolase family 7 RIFIN PF02009.16 KKK13555.1 - 0.26 11.1 2.0 0.35 10.7 2.0 1.3 1 0 0 1 1 1 0 Rifin Fer4_20 PF14691.6 KKK13555.1 - 3.8 7.3 6.0 5.7 6.7 0.5 2.3 2 0 0 2 2 2 0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Tyrosinase PF00264.20 KKK13556.1 - 6e-30 105.2 9.3 9.1e-30 104.6 9.3 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase DPPIV_N PF00930.21 KKK13557.1 - 3.5e-06 26.0 0.1 8.1e-06 24.8 0.0 1.6 2 0 0 2 2 2 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region DPPIV_N PF00930.21 KKK13558.1 - 6.9e-13 48.1 2.5 9.4e-09 34.5 1.0 2.1 2 0 0 2 2 2 2 Dipeptidyl peptidase IV (DPP IV) N-terminal region MFS_1 PF07690.16 KKK13559.1 - 3.3e-30 105.2 28.9 3.3e-30 105.2 28.9 1.8 2 1 1 3 3 3 1 Major Facilitator Superfamily Beta-lactamase PF00144.24 KKK13560.1 - 5.6e-40 137.6 0.0 1.5e-39 136.2 0.0 1.6 1 1 0 1 1 1 1 Beta-lactamase Beta-lactamase2 PF13354.6 KKK13560.1 - 0.18 11.4 0.0 0.35 10.4 0.0 1.4 1 0 0 1 1 1 0 Beta-lactamase enzyme family Abhydrolase_3 PF07859.13 KKK13561.1 - 8.2e-24 84.6 0.0 1.2e-23 84.1 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KKK13561.1 - 3.5e-18 65.6 0.0 4.9e-18 65.2 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 KKK13561.1 - 0.0013 18.3 0.0 0.82 9.1 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Glyco_transf_54 PF04666.13 KKK13561.1 - 0.063 12.1 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region Pro-kuma_activ PF09286.11 KKK13562.1 - 1.6e-41 142.0 0.0 3e-41 141.0 0.0 1.5 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain dCMP_cyt_deam_1 PF00383.23 KKK13563.1 - 3.4e-10 39.7 0.0 5.8e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KKK13563.1 - 5.5e-07 29.4 0.1 8.8e-06 25.5 0.1 2.2 1 1 0 1 1 1 1 MafB19-like deaminase Bd3614-deam PF14439.6 KKK13563.1 - 0.35 10.9 0.9 0.87 9.7 0.9 1.6 1 1 0 1 1 1 0 Bd3614-like deaminase Glyco_hydro_28 PF00295.17 KKK13564.1 - 7.2e-121 403.2 20.1 8.2e-121 403.0 20.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 DUF2993 PF11209.8 KKK13564.1 - 0.038 14.2 1.1 0.15 12.3 0.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2993) V-ATPase_H_N PF03224.14 KKK13589.1 - 1.5e-86 290.6 0.0 2.1e-86 290.1 0.0 1.2 1 0 0 1 1 1 1 V-ATPase subunit H V-ATPase_H_C PF11698.8 KKK13589.1 - 1.3e-37 128.5 0.0 8.2e-37 125.9 0.0 2.3 2 0 0 2 2 2 1 V-ATPase subunit H TMF_TATA_bd PF12325.8 KKK13590.1 - 4.8e-40 136.4 11.4 4.8e-40 136.4 11.4 6.4 2 1 3 6 6 6 1 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.8 KKK13590.1 - 1e-17 63.9 12.5 1e-17 63.9 12.5 8.4 6 3 3 9 9 9 2 TATA element modulatory factor 1 DNA binding ATG16 PF08614.11 KKK13590.1 - 2.2e-05 24.8 6.1 2.2e-05 24.8 6.1 5.4 3 1 2 5 5 5 2 Autophagy protein 16 (ATG16) Rab5-bind PF09311.11 KKK13590.1 - 0.0011 18.4 34.6 0.0011 18.4 34.6 3.6 2 1 2 4 4 4 2 Rabaptin-like protein SlyX PF04102.12 KKK13590.1 - 0.016 15.8 2.2 0.016 15.8 2.2 9.8 5 2 6 11 11 11 0 SlyX DUF2443 PF10398.9 KKK13590.1 - 5 7.2 6.4 5.9 7.0 0.1 4.2 4 0 0 4 4 4 0 Protein of unknown function (DUF2443) NPV_P10 PF05531.12 KKK13590.1 - 5.3 7.6 24.8 0.54 10.8 4.9 5.9 5 2 0 5 5 5 0 Nucleopolyhedrovirus P10 protein Filament PF00038.21 KKK13590.1 - 8.5 5.9 77.8 0.25 10.9 6.8 3.6 2 1 1 3 3 3 0 Intermediate filament protein Laminin_II PF06009.12 KKK13590.1 - 9.4 6.2 56.9 0.12 12.4 9.8 5.8 2 2 2 5 5 5 0 Laminin Domain II AAA PF00004.29 KKK13591.1 - 4.8e-15 56.2 0.0 9e-15 55.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_10 PF17872.1 KKK13591.1 - 1.9e-12 47.2 0.7 8.5e-12 45.1 0.6 2.2 2 1 0 2 2 1 1 AAA lid domain AAA_22 PF13401.6 KKK13591.1 - 4.4e-10 40.0 0.0 1.4e-09 38.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KKK13591.1 - 1.9e-09 38.1 1.0 7.4e-09 36.2 0.0 2.5 2 2 0 2 2 2 1 AAA ATPase domain BAH PF01426.18 KKK13591.1 - 2.4e-05 24.2 0.0 6.2e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 BAH domain AAA_19 PF13245.6 KKK13591.1 - 0.002 18.5 0.1 0.006 16.9 0.1 1.8 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 KKK13591.1 - 0.0023 18.2 0.0 0.007 16.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KKK13591.1 - 0.0055 16.9 0.0 0.1 12.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KKK13591.1 - 0.015 15.2 0.0 0.05 13.5 0.0 1.9 1 1 0 1 1 1 0 NACHT domain AAA_11 PF13086.6 KKK13591.1 - 0.015 15.1 0.5 0.035 13.9 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KKK13591.1 - 0.045 14.3 0.0 0.11 13.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_32 PF13654.6 KKK13591.1 - 0.049 12.4 0.0 0.087 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 KKK13591.1 - 0.051 12.8 0.0 0.11 11.7 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) PIF1 PF05970.14 KKK13591.1 - 0.082 12.1 0.0 0.19 10.9 0.0 1.5 1 0 0 1 1 1 0 PIF1-like helicase ATPase_2 PF01637.18 KKK13591.1 - 0.12 12.3 0.0 2.8 7.8 0.0 2.3 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea ssDBP PF17878.1 KKK13591.1 - 0.12 12.6 0.0 0.29 11.4 0.0 1.6 1 0 0 1 1 1 0 Single-stranded DNA-binding protein Kinesin PF00225.23 KKK13591.1 - 0.18 10.7 0.0 0.32 9.9 0.0 1.4 1 0 0 1 1 1 0 Kinesin motor domain AAA_30 PF13604.6 KKK13591.1 - 0.48 10.1 3.2 0.21 11.3 0.3 1.9 2 0 0 2 2 2 0 AAA domain KH_1 PF00013.29 KKK13592.1 - 0.0097 15.7 0.0 0.59 10.0 0.0 2.4 2 0 0 2 2 2 2 KH domain Ank_2 PF12796.7 KKK13593.1 - 9.6e-38 128.7 2.9 1.5e-13 51.1 0.6 3.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KKK13593.1 - 2.5e-32 110.5 1.2 1.7e-07 31.4 0.1 4.2 2 2 4 6 6 6 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 KKK13593.1 - 6.3e-26 90.4 0.4 5e-07 30.1 0.0 5.1 2 1 4 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KKK13593.1 - 1.2e-25 86.8 0.8 2.1e-05 24.6 0.0 6.2 6 0 0 6 6 6 5 Ankyrin repeat Ank PF00023.30 KKK13593.1 - 5e-22 77.3 3.9 1.9e-05 24.9 0.0 6.1 6 0 0 6 6 6 4 Ankyrin repeat WD40 PF00400.32 KKK13594.1 - 2.7e-44 148.2 11.7 3.3e-09 37.2 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKK13594.1 - 1.9e-05 24.9 0.2 7.7 6.9 0.0 4.6 2 2 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KKK13594.1 - 0.064 11.9 2.7 11 4.6 0.0 4.2 2 1 2 5 5 5 0 Nucleoporin Nup120/160 WD40_like PF17005.5 KKK13594.1 - 0.12 11.6 0.0 0.25 10.6 0.0 1.5 2 0 0 2 2 2 0 WD40-like domain Prefoldin PF02996.17 KKK13595.1 - 6.8e-13 48.6 1.0 4.9e-12 45.8 1.0 2.0 1 1 0 1 1 1 1 Prefoldin subunit CLZ PF16526.5 KKK13595.1 - 0.011 16.0 1.3 0.52 10.7 0.1 2.4 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DASH_Hsk3 PF08227.11 KKK13595.1 - 0.014 15.7 1.9 0.12 12.7 0.1 2.3 2 0 0 2 2 2 0 DASH complex subunit Hsk3 like Med28 PF11594.8 KKK13595.1 - 0.06 13.4 0.1 0.14 12.2 0.0 1.6 2 0 0 2 2 2 0 Mediator complex subunit 28 DUF883 PF05957.13 KKK13595.1 - 0.12 13.0 1.2 8.4 7.1 0.6 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Dabb PF07876.12 KKK13596.1 - 2.4e-23 82.6 0.0 2.7e-23 82.4 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain DUF4390 PF14334.6 KKK13596.1 - 0.22 10.9 0.0 0.3 10.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4390) Fungal_trans_2 PF11951.8 KKK13597.1 - 4e-60 203.6 1.5 6.1e-60 203.1 1.5 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Hormone_recep PF00104.30 KKK13597.1 - 0.013 15.1 0.0 0.024 14.2 0.0 1.4 1 0 0 1 1 1 0 Ligand-binding domain of nuclear hormone receptor ATP-synt_10 PF05176.14 KKK13607.1 - 5.5e-85 284.7 0.0 7.7e-85 284.2 0.0 1.1 1 0 0 1 1 1 1 ATP10 protein Zn_clus PF00172.18 KKK13608.1 - 0.018 15.2 6.9 0.042 14.0 6.9 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-BED PF02892.15 KKK13608.1 - 0.057 13.5 0.5 0.14 12.2 0.5 1.6 1 0 0 1 1 1 0 BED zinc finger DNA_pol_B_palm PF14792.6 KKK13609.1 - 7.8e-34 116.3 0.0 1.5e-33 115.4 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.6 KKK13609.1 - 3e-24 85.0 0.0 6.9e-24 83.8 0.0 1.7 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.9 KKK13609.1 - 5.4e-18 64.6 0.1 4.7e-17 61.6 0.0 2.4 2 0 0 2 2 2 1 Fingers domain of DNA polymerase lambda HHH_8 PF14716.6 KKK13609.1 - 9.4e-18 64.3 0.1 2e-17 63.3 0.1 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix domain BRCT PF00533.26 KKK13609.1 - 0.0015 18.9 0.0 0.0031 17.9 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain NTP_transf_2 PF01909.23 KKK13609.1 - 0.022 15.0 0.0 0.063 13.6 0.0 1.8 1 0 0 1 1 1 0 Nucleotidyltransferase domain HHH_5 PF14520.6 KKK13609.1 - 0.051 14.2 0.0 18 6.0 0.0 2.5 2 0 0 2 2 2 0 Helix-hairpin-helix domain DENN PF02141.21 KKK13622.1 - 5.4e-57 192.7 0.1 9.3e-57 192.0 0.1 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 KKK13622.1 - 1.1e-14 55.0 0.0 2.3e-14 53.8 0.0 1.6 1 0 0 1 1 1 1 uDENN domain dDENN PF03455.19 KKK13622.1 - 1.3e-12 47.5 0.9 6.3e-12 45.3 0.4 2.5 2 0 0 2 2 2 1 dDENN domain C1_2 PF03107.16 KKK13622.1 - 1e-06 29.0 4.5 1.9e-06 28.1 4.5 1.5 1 0 0 1 1 1 1 C1 domain C1_1 PF00130.22 KKK13622.1 - 0.0022 17.8 10.4 0.0043 16.9 10.4 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Zf_RING PF16744.5 KKK13622.1 - 0.027 14.6 5.2 0.058 13.5 5.2 1.5 1 0 0 1 1 1 0 KIAA1045 RING finger PHD PF00628.29 KKK13622.1 - 0.2 11.6 9.6 0.052 13.4 6.0 1.9 1 1 1 2 2 2 0 PHD-finger Zn_ribbon_17 PF17120.5 KKK13622.1 - 0.37 10.5 6.7 0.81 9.4 6.7 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type DHquinase_I PF01487.15 KKK13623.1 - 1.3e-34 120.5 0.0 2.1e-34 119.8 0.0 1.3 1 0 0 1 1 1 1 Type I 3-dehydroquinase Fungal_trans PF04082.18 KKK13623.1 - 3.8e-17 62.2 0.0 6.7e-17 61.4 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF3632 PF12311.8 KKK13623.1 - 1.7e-05 25.3 0.0 0.00064 20.2 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3632) Zn_clus PF00172.18 KKK13623.1 - 0.00017 21.6 17.5 0.00017 21.6 17.5 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BRO1 PF03097.18 KKK13624.1 - 2.9e-120 401.7 1.3 4.9e-120 400.9 0.0 2.0 2 1 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 KKK13624.1 - 7.1e-84 281.6 14.3 7.1e-84 281.6 14.3 1.8 2 0 0 2 2 2 1 ALIX V-shaped domain binding to HIV MSA-2c PF12238.8 KKK13624.1 - 1.6 8.7 8.6 4.8 7.1 8.6 1.9 1 1 0 1 1 1 0 Merozoite surface antigen 2c Mito_carr PF00153.27 KKK13625.1 - 8.4e-42 141.0 4.2 2.1e-15 56.4 0.1 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein Thiolase_N PF00108.23 KKK13626.1 - 2.9e-17 62.9 0.0 8.6e-17 61.3 0.0 1.8 1 1 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KKK13626.1 - 3.4e-11 42.8 0.6 9.5e-11 41.4 0.6 1.8 1 1 0 1 1 1 1 Thiolase, C-terminal domain ACP_syn_III PF08545.10 KKK13626.1 - 1.1e-07 31.6 0.2 1.2e-05 25.1 0.1 2.7 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.26 KKK13626.1 - 2.7e-05 23.9 0.1 5.6e-05 22.8 0.1 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain SpoVAD PF07451.11 KKK13626.1 - 0.027 13.2 0.1 0.062 12.0 0.1 1.6 1 0 0 1 1 1 0 Stage V sporulation protein AD (SpoVAD) Peptidase_S49 PF01343.18 KKK13626.1 - 0.092 12.7 0.0 1 9.3 0.0 2.3 2 1 0 2 2 2 0 Peptidase family S49 SMN PF06003.12 KKK13627.1 - 1e-06 28.3 5.0 0.00017 21.0 0.9 2.3 1 1 1 2 2 2 2 Survival motor neuron protein (SMN) CHD5 PF04420.14 KKK13628.1 - 1.8e-60 203.4 3.5 2.3e-60 203.1 3.5 1.1 1 0 0 1 1 1 1 CHD5-like protein VPS11_C PF12451.8 KKK13628.1 - 7.3 6.9 5.8 39 4.6 1.8 2.2 1 1 1 2 2 2 0 Vacuolar protein sorting protein 11 C terminal PPTA PF01239.22 KKK13629.1 - 0.011 15.5 1.2 0.66 9.8 1.3 2.5 2 0 0 2 2 2 0 Protein prenyltransferase alpha subunit repeat RRM_1 PF00076.22 KKK13630.1 - 2.6e-13 49.6 0.0 5.2e-13 48.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KKK13630.1 - 0.023 14.7 0.1 0.074 13.1 0.1 1.8 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif ADH_N PF08240.12 KKK13631.1 - 1.1e-20 73.6 0.6 1.7e-20 72.9 0.6 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KKK13631.1 - 2.8e-16 59.7 0.1 5.3e-16 58.8 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_7 PF13241.6 KKK13631.1 - 0.00022 21.6 0.0 0.00045 20.6 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding Glu_dehyd_C PF16912.5 KKK13631.1 - 0.0023 17.4 0.2 0.0041 16.6 0.2 1.4 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus DAO PF01266.24 KKK13631.1 - 0.0065 16.1 0.3 0.0094 15.6 0.3 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KKK13631.1 - 0.0067 15.7 0.3 0.0096 15.2 0.3 1.2 1 0 0 1 1 1 1 FAD binding domain ADH_zinc_N_2 PF13602.6 KKK13631.1 - 0.072 14.1 0.0 0.15 13.1 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Pyr_redox_2 PF07992.14 KKK13631.1 - 0.11 11.7 0.1 0.16 11.1 0.1 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KKK13631.1 - 0.21 10.8 0.0 0.29 10.4 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF3431 PF11913.8 KKK13646.1 - 1.2e-88 296.4 0.4 1.9e-88 295.9 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) CoaE PF01121.20 KKK13646.1 - 1.9e-39 135.2 0.0 3.4e-39 134.4 0.0 1.3 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_18 PF13238.6 KKK13646.1 - 0.029 14.9 0.1 0.76 10.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain zf-CHCC PF10276.9 KKK13647.1 - 1.1e-15 57.3 2.0 1.8e-15 56.7 2.0 1.3 1 0 0 1 1 1 1 Zinc-finger domain UPF0047 PF01894.17 KKK13648.1 - 6.2e-37 126.3 0.0 7e-37 126.1 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 MPP6 PF10175.9 KKK13650.1 - 2.8e-06 27.9 14.1 1.2e-05 25.9 14.1 1.9 1 1 0 1 1 1 1 M-phase phosphoprotein 6 Utp14 PF04615.13 KKK13650.1 - 0.047 12.3 11.6 0.083 11.5 11.6 1.3 1 1 0 1 1 1 0 Utp14 protein RNA_pol_Rpc4 PF05132.14 KKK13650.1 - 1.7 9.1 10.9 0.045 14.2 2.2 2.2 2 1 0 2 2 2 0 RNA polymerase III RPC4 DUF4592 PF15262.6 KKK13650.1 - 2.8 8.6 13.9 3.4 8.4 5.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4592) TFIIF_alpha PF05793.12 KKK13650.1 - 3.9 6.0 16.1 0.014 14.0 4.0 2.0 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) HLH PF00010.26 KKK13657.1 - 9.7e-07 28.7 0.0 2e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain ORC6 PF05460.13 KKK13657.1 - 1.5 8.0 9.9 3 7.0 9.9 1.4 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) TMEM135_C_rich PF15982.5 KKK13658.1 - 0.00028 21.5 0.4 0.001 19.7 0.4 1.9 1 1 0 1 1 1 1 N-terminal cysteine-rich region of Transmembrane protein 135 Cation_ATPase_C PF00689.21 KKK13658.1 - 0.0015 18.2 0.0 0.0031 17.2 0.0 1.4 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus CENP-Q PF13094.6 KKK13659.1 - 1.4e-43 149.0 9.6 2.6e-43 148.1 9.6 1.4 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit MCR_C PF04609.12 KKK13659.1 - 0.0059 15.7 0.4 0.24 10.5 0.0 2.2 2 0 0 2 2 2 1 Methyl-coenzyme M reductase operon protein C PRANC PF09372.10 KKK13659.1 - 0.1 12.9 0.3 0.74 10.2 0.0 2.3 2 0 0 2 2 2 0 PRANC domain DDE_Tnp_4 PF13359.6 KKK13659.1 - 0.13 11.9 0.0 0.26 10.9 0.0 1.5 1 0 0 1 1 1 0 DDE superfamily endonuclease LCIB_C_CA PF18599.1 KKK13659.1 - 0.29 10.4 0.7 1.2 8.4 0.0 2.0 2 0 0 2 2 2 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases DUF4337 PF14235.6 KKK13659.1 - 0.36 10.9 5.3 0.97 9.5 5.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Sec8_exocyst PF04048.14 KKK13659.1 - 0.93 9.4 5.2 0.66 9.9 1.2 2.5 2 1 0 2 2 2 0 Sec8 exocyst complex component specific domain SlyX PF04102.12 KKK13659.1 - 4.1 8.1 8.6 4.5 8.0 2.4 3.5 4 0 0 4 4 4 0 SlyX Ribonuclease_3 PF00636.26 KKK13664.1 - 7.7e-42 142.2 0.0 8.4e-20 71.4 0.0 3.5 3 0 0 3 3 3 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 KKK13664.1 - 7e-24 84.4 0.0 1e-11 45.1 0.0 3.9 2 2 0 2 2 2 2 Ribonuclease-III-like Dicer_dimer PF03368.14 KKK13664.1 - 2.6e-21 75.6 0.0 2.4e-20 72.5 0.0 2.6 2 0 0 2 2 2 1 Dicer dimerisation domain Helicase_C PF00271.31 KKK13664.1 - 4.3e-17 62.4 0.1 1.3e-16 60.9 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KKK13664.1 - 1.9e-13 50.8 0.1 6.1e-13 49.1 0.1 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KKK13664.1 - 3.2e-09 36.8 0.0 2.2e-08 34.1 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase dsrm PF00035.26 KKK13664.1 - 0.00018 22.1 0.0 0.59 10.9 0.0 2.8 2 0 0 2 2 2 2 Double-stranded RNA binding motif AAA_22 PF13401.6 KKK13664.1 - 0.17 12.1 0.2 0.65 10.3 0.1 2.0 2 0 0 2 2 2 0 AAA domain TAP42 PF04177.12 KKK13665.1 - 5.8e-104 347.6 6.4 6.6e-104 347.5 6.4 1.0 1 0 0 1 1 1 1 TAP42-like family Svf1_C PF17187.4 KKK13666.1 - 1.8e-60 203.5 0.0 2.4e-60 203.1 0.0 1.1 1 0 0 1 1 1 1 Svf1-like C-terminal lipocalin-like domain Svf1 PF08622.10 KKK13666.1 - 3.6e-34 118.2 0.0 6.2e-34 117.4 0.0 1.3 1 0 0 1 1 1 1 Svf1-like N-terminal lipocalin domain AAA_6 PF12774.7 KKK13667.1 - 3.8e-126 420.5 0.1 2.2e-124 414.7 0.0 3.1 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N1 PF08385.12 KKK13667.1 - 9.6e-125 417.4 11.5 9.6e-125 417.4 11.5 4.5 4 1 0 4 4 4 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.13 KKK13667.1 - 2.6e-115 385.7 7.5 2.6e-115 385.7 7.5 4.9 5 1 0 5 5 4 1 Dynein heavy chain, N-terminal region 2 AAA_9 PF12781.7 KKK13667.1 - 3.7e-75 251.8 1.1 8.3e-74 247.4 0.4 3.8 3 0 0 3 3 2 1 ATP-binding dynein motor region AAA_8 PF12780.7 KKK13667.1 - 2.5e-67 227.0 0.0 1.7e-66 224.2 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_7 PF12775.7 KKK13667.1 - 1.2e-41 142.2 0.0 3.9e-36 124.3 0.0 4.6 4 0 0 4 4 4 2 P-loop containing dynein motor region AAA_5 PF07728.14 KKK13667.1 - 1.6e-31 109.1 0.0 7e-11 42.3 0.0 5.8 4 1 0 4 4 4 4 AAA domain (dynein-related subfamily) Dynein_heavy PF03028.15 KKK13667.1 - 4.9e-31 107.3 0.1 1.6e-26 92.7 0.0 4.6 4 0 0 4 4 3 1 Dynein heavy chain region D6 P-loop domain MT PF12777.7 KKK13667.1 - 2.9e-30 105.5 11.2 1.8e-27 96.3 11.2 2.4 1 1 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_lid_11 PF18198.1 KKK13667.1 - 5.3e-30 104.4 0.0 1.3e-29 103.1 0.0 1.7 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_AAA_lid PF17852.1 KKK13667.1 - 1.6e-20 73.5 1.2 2.9e-19 69.4 0.1 3.3 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA PF00004.29 KKK13667.1 - 2.3e-15 57.2 0.0 0.00011 22.6 0.0 5.4 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KKK13667.1 - 1.2e-14 54.8 2.4 0.0074 16.6 0.0 7.7 6 1 1 7 7 7 2 AAA domain AAA_18 PF13238.6 KKK13667.1 - 5e-11 43.3 0.2 0.096 13.2 0.0 5.7 5 0 0 5 5 4 3 AAA domain AAA_16 PF13191.6 KKK13667.1 - 2.1e-10 41.2 0.7 1.2 9.5 0.0 8.0 7 0 0 7 7 6 1 AAA ATPase domain AAA_33 PF13671.6 KKK13667.1 - 5.3e-09 36.4 3.5 0.37 11.0 0.0 5.7 6 0 0 6 6 4 3 AAA domain ABC_tran PF00005.27 KKK13667.1 - 2.2e-06 28.2 0.2 0.52 10.8 0.1 5.5 4 0 0 4 4 3 1 ABC transporter T2SSE PF00437.20 KKK13667.1 - 2.6e-06 26.7 0.0 0.0073 15.4 0.0 3.5 3 0 0 3 3 3 1 Type II/IV secretion system protein AAA_lid_1 PF17857.1 KKK13667.1 - 6.8e-06 26.2 0.4 0.0049 17.1 0.0 4.1 3 0 0 3 3 3 1 AAA+ lid domain RsgA_GTPase PF03193.16 KKK13667.1 - 4.2e-05 23.5 0.0 5.8 6.8 0.0 4.5 4 0 0 4 4 4 0 RsgA GTPase AAA_29 PF13555.6 KKK13667.1 - 5.8e-05 22.8 0.1 2.2 8.1 0.0 3.6 3 0 0 3 3 3 2 P-loop containing region of AAA domain Mg_chelatase PF01078.21 KKK13667.1 - 9.7e-05 21.8 0.9 0.57 9.5 0.0 3.7 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI Taxilin PF09728.9 KKK13667.1 - 0.00014 21.2 0.3 0.00014 21.2 0.3 3.4 3 0 0 3 3 2 1 Myosin-like coiled-coil protein FtsK_SpoIIIE PF01580.18 KKK13667.1 - 0.00035 20.0 0.0 1.6 8.0 0.0 3.9 3 0 0 3 3 3 1 FtsK/SpoIIIE family AAA_30 PF13604.6 KKK13667.1 - 0.00037 20.3 0.7 23 4.7 0.0 5.0 5 0 0 5 5 4 0 AAA domain AAA_25 PF13481.6 KKK13667.1 - 0.0013 18.4 0.0 0.48 10.0 0.0 3.6 3 0 0 3 3 2 1 AAA domain AAA_24 PF13479.6 KKK13667.1 - 0.0013 18.5 0.2 22 4.7 0.0 4.7 4 0 0 4 4 4 0 AAA domain DUF3867 PF12983.7 KKK13667.1 - 0.0015 18.6 0.5 0.0015 18.6 0.5 3.4 4 0 0 4 4 2 1 Protein of unknown function (DUF3867) AAA_19 PF13245.6 KKK13667.1 - 0.0023 18.3 3.7 0.21 11.9 0.0 4.6 5 0 0 5 5 4 1 AAA domain IstB_IS21 PF01695.17 KKK13667.1 - 0.0043 16.8 0.4 0.53 10.0 0.0 4.0 4 0 0 4 4 4 1 IstB-like ATP binding protein RNA_helicase PF00910.22 KKK13667.1 - 0.0044 17.4 0.2 19 5.7 0.1 5.0 5 0 0 5 5 5 0 RNA helicase Rad17 PF03215.15 KKK13667.1 - 0.0059 16.6 0.3 5.6 6.8 0.0 4.3 5 0 0 5 5 3 0 Rad17 P-loop domain AAA_21 PF13304.6 KKK13667.1 - 0.0066 16.3 0.5 9.4 5.9 0.0 3.7 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system Zeta_toxin PF06414.12 KKK13667.1 - 0.027 13.7 0.1 27 3.9 0.0 3.8 3 0 0 3 3 3 0 Zeta toxin MbeB_N PF04837.12 KKK13667.1 - 0.12 12.7 1.9 2.3 8.6 0.1 3.6 2 0 0 2 2 2 0 MbeB-like, N-term conserved region Vps23_core PF09454.10 KKK13667.1 - 0.14 12.1 0.5 9.1 6.3 0.3 3.1 2 0 0 2 2 2 0 Vps23 core domain PduV-EutP PF10662.9 KKK13667.1 - 0.33 10.7 2.9 11 5.7 0.1 4.1 4 0 0 4 4 4 0 Ethanolamine utilisation - propanediol utilisation DUF3450 PF11932.8 KKK13667.1 - 0.33 10.2 18.9 0.096 12.0 2.7 3.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) DUF4482 PF14818.6 KKK13667.1 - 1.6 9.6 13.4 31 5.4 0.0 3.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4482) PspA_IM30 PF04012.12 KKK13667.1 - 2.3 7.8 25.7 0.55 9.8 1.8 4.1 3 0 0 3 3 3 0 PspA/IM30 family Phage_GP20 PF06810.11 KKK13667.1 - 3.1 7.6 21.7 2 8.2 0.5 3.8 3 0 0 3 3 3 0 Phage minor structural protein GP20 DUF87 PF01935.17 KKK13667.1 - 3.1 7.8 6.2 46 4.0 0.1 4.4 3 0 0 3 3 3 0 Helicase HerA, central domain BRE1 PF08647.11 KKK13667.1 - 4.2 7.5 25.6 0.0072 16.4 1.9 5.7 4 1 0 4 4 4 0 BRE1 E3 ubiquitin ligase AAA_17 PF13207.6 KKK13667.1 - 4.7 7.6 6.6 1.5e+02 2.8 0.0 4.8 4 0 0 4 4 4 0 AAA domain Porphobil_deam PF01379.20 KKK13668.1 - 1.9e-71 239.8 0.0 2.4e-71 239.5 0.0 1.1 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 KKK13668.1 - 1.3e-18 67.1 0.0 2.4e-18 66.2 0.0 1.4 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain Ribosomal_L23 PF00276.20 KKK13669.1 - 7.7e-11 42.2 0.0 1.3e-10 41.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L23 DUF2389 PF09493.10 KKK13669.1 - 0.025 15.2 0.1 0.045 14.4 0.1 1.4 1 0 0 1 1 1 0 Tryptophan-rich protein (DUF2389) Lon_C PF05362.13 KKK13670.1 - 4.5e-46 157.0 0.5 9.2e-43 146.2 0.1 3.2 2 1 1 3 3 3 2 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 KKK13670.1 - 2.3e-29 102.8 0.0 3.8e-29 102.1 0.0 1.4 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 KKK13670.1 - 2.7e-23 82.8 0.0 1.4e-22 80.5 0.0 2.3 3 0 0 3 3 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KKK13670.1 - 8.6e-08 32.3 0.0 2.9e-07 30.6 0.0 2.0 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KKK13670.1 - 8.8e-07 29.5 0.4 6.2e-06 26.7 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_3 PF07726.11 KKK13670.1 - 0.00013 21.8 0.0 0.00039 20.3 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KKK13670.1 - 0.00025 20.8 0.1 0.0012 18.7 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 KKK13670.1 - 0.00097 19.3 0.0 0.0035 17.5 0.0 2.0 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 KKK13670.1 - 0.0016 18.7 0.2 0.024 14.9 0.0 2.9 2 1 0 2 2 1 1 AAA domain TIP49 PF06068.13 KKK13670.1 - 0.0017 17.6 0.0 0.0036 16.6 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 KKK13670.1 - 0.0041 17.3 0.0 0.015 15.4 0.0 2.0 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KKK13670.1 - 0.0073 16.1 0.0 0.019 14.7 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein Zeta_toxin PF06414.12 KKK13670.1 - 0.02 14.2 0.1 0.13 11.6 0.0 2.1 2 0 0 2 2 2 0 Zeta toxin AAA_11 PF13086.6 KKK13670.1 - 0.023 14.5 0.0 0.059 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KKK13670.1 - 0.028 15.0 0.0 0.077 13.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 KKK13670.1 - 0.036 13.5 0.1 0.12 11.8 0.1 1.8 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NACHT PF05729.12 KKK13670.1 - 0.038 13.9 0.1 0.18 11.7 0.0 2.2 2 0 0 2 2 1 0 NACHT domain TsaE PF02367.17 KKK13670.1 - 0.052 13.6 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_25 PF13481.6 KKK13670.1 - 0.052 13.1 0.0 0.13 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 KKK13670.1 - 0.073 13.0 0.1 0.23 11.4 0.0 1.8 2 0 0 2 2 2 0 Rad17 P-loop domain RNA_helicase PF00910.22 KKK13670.1 - 0.093 13.1 0.0 0.22 11.9 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_30 PF13604.6 KKK13670.1 - 0.11 12.2 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 KKK13670.1 - 0.11 11.9 0.0 0.26 10.7 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_14 PF13173.6 KKK13670.1 - 0.17 11.9 0.0 0.37 10.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KKK13670.1 - 0.17 11.4 0.0 0.34 10.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region NTPase_1 PF03266.15 KKK13670.1 - 0.18 11.7 0.3 0.59 10.0 0.0 2.0 2 0 0 2 2 2 0 NTPase AAA_PrkA PF08298.11 KKK13670.1 - 0.2 10.5 0.0 1.7 7.5 0.0 2.1 2 0 0 2 2 2 0 PrkA AAA domain AAA_23 PF13476.6 KKK13670.1 - 0.21 12.0 0.0 0.21 12.0 0.0 2.7 1 1 0 2 2 1 0 AAA domain Rubis-subs-bind PF09273.11 KKK13670.1 - 2.7 8.7 6.4 15 6.3 1.7 3.2 1 1 0 2 2 2 0 Rubisco LSMT substrate-binding MatP_C PF17414.2 KKK13671.1 - 0.18 12.0 4.3 0.24 11.6 0.9 3.0 3 0 0 3 3 3 0 MatP C-terminal ribbon-helix-helix domain MCC-bdg_PDZ PF10506.9 KKK13671.1 - 1.6 8.8 11.3 0.35 10.9 0.2 4.3 4 0 0 4 4 4 0 PDZ domain of MCC-2 bdg protein for Usher syndrome Cytochrom_C552 PF02335.15 KKK13671.1 - 3.2 6.6 7.1 0.52 9.2 2.9 1.8 2 0 0 2 2 2 0 Cytochrome c552 CP12 PF02672.15 KKK13672.1 - 0.063 14.0 0.1 0.1 13.4 0.1 1.4 1 0 0 1 1 1 0 CP12 domain DUF5601 PF18151.1 KKK13672.1 - 0.14 12.5 0.0 0.18 12.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5601) ADPRTs_Tse2 PF18648.1 KKK13673.1 - 0.03 14.4 0.0 0.13 12.3 0.0 2.0 2 0 0 2 2 2 0 Tse2 ADP-ribosyltransferase toxins SLD3 PF08639.10 KKK13674.1 - 1.8e-161 538.6 3.3 3e-161 537.8 3.3 1.4 1 0 0 1 1 1 1 DNA replication regulator SLD3 ATP_bind_1 PF03029.17 KKK13675.1 - 1.8e-77 260.4 0.0 3.2e-77 259.6 0.0 1.4 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_16 PF13191.6 KKK13675.1 - 6.1e-05 23.5 0.0 0.0088 16.4 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_14 PF13173.6 KKK13675.1 - 0.00039 20.5 0.0 0.001 19.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KKK13675.1 - 0.00073 19.9 0.2 0.025 14.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain CLP1_P PF16575.5 KKK13675.1 - 0.002 18.0 0.0 0.0064 16.3 0.0 1.8 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop RNA_helicase PF00910.22 KKK13675.1 - 0.0037 17.6 0.0 0.0093 16.3 0.0 1.7 1 0 0 1 1 1 1 RNA helicase AAA_22 PF13401.6 KKK13675.1 - 0.0071 16.6 0.0 0.022 15.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 KKK13675.1 - 0.0083 16.1 0.0 0.018 15.0 0.0 1.6 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 KKK13675.1 - 0.0095 15.7 0.0 0.023 14.4 0.0 1.7 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 KKK13675.1 - 0.01 14.9 0.0 0.019 14.0 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein NACHT PF05729.12 KKK13675.1 - 0.011 15.7 0.0 0.026 14.5 0.0 1.6 2 0 0 2 2 1 0 NACHT domain AAA PF00004.29 KKK13675.1 - 0.012 16.0 0.0 0.031 14.7 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) GTP_EFTU PF00009.27 KKK13675.1 - 0.012 15.1 0.1 1.8 8.0 0.1 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain ATPase_2 PF01637.18 KKK13675.1 - 0.013 15.5 0.0 0.062 13.2 0.0 1.9 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_7 PF12775.7 KKK13675.1 - 0.014 15.0 0.1 0.032 13.7 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region ABC_tran PF00005.27 KKK13675.1 - 0.017 15.6 0.0 0.17 12.4 0.0 2.1 2 0 0 2 2 2 0 ABC transporter AAA_30 PF13604.6 KKK13675.1 - 0.017 14.8 0.1 0.067 12.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KKK13675.1 - 0.017 15.6 0.0 0.046 14.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KKK13675.1 - 0.018 15.2 0.0 0.029 14.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain KAP_NTPase PF07693.14 KKK13675.1 - 0.019 14.3 0.0 0.038 13.2 0.0 1.5 1 1 0 1 1 1 0 KAP family P-loop domain AAA_17 PF13207.6 KKK13675.1 - 0.023 15.1 1.3 0.83 10.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 KKK13675.1 - 0.027 14.1 0.2 0.61 9.6 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 KKK13675.1 - 0.035 14.0 0.3 0.67 9.8 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase NTPase_1 PF03266.15 KKK13675.1 - 0.046 13.6 0.0 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 NTPase Septin PF00735.18 KKK13675.1 - 0.047 13.0 0.1 0.11 11.7 0.0 1.6 2 0 0 2 2 2 0 Septin PduV-EutP PF10662.9 KKK13675.1 - 0.056 13.2 0.0 1.2 8.8 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation SRP54 PF00448.22 KKK13675.1 - 0.059 13.0 0.0 0.15 11.7 0.0 1.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain NB-ARC PF00931.22 KKK13675.1 - 0.071 12.3 0.0 0.14 11.3 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain ATPase PF06745.13 KKK13675.1 - 0.091 12.1 0.0 0.25 10.7 0.0 1.7 2 0 0 2 2 2 0 KaiC CbiA PF01656.23 KKK13675.1 - 0.22 11.6 0.0 0.28 11.2 0.0 1.4 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain S-AdoMet_synt_C PF02773.16 KKK13676.1 - 1.4e-65 219.4 0.2 2.7e-65 218.5 0.0 1.6 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_N PF00438.20 KKK13676.1 - 5.5e-44 148.9 0.1 1.2e-43 147.9 0.1 1.6 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain S-AdoMet_synt_M PF02772.16 KKK13676.1 - 1.1e-25 90.2 0.1 1.5e-15 57.5 0.0 2.5 1 1 1 2 2 2 2 S-adenosylmethionine synthetase, central domain RNase_H PF00075.24 KKK13677.1 - 1.7e-23 83.4 0.0 2.2e-23 83.0 0.0 1.1 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.6 KKK13677.1 - 3.4e-05 23.7 0.0 0.17 11.7 0.0 2.2 2 0 0 2 2 2 2 Reverse transcriptase-like Apq12 PF12716.7 KKK13678.1 - 2.1e-19 69.2 14.9 3.6e-19 68.4 14.9 1.4 1 0 0 1 1 1 1 Nuclear pore assembly and biogenesis SPC22 PF04573.12 KKK13693.1 - 4.7e-41 140.1 0.0 5.2e-29 100.9 0.0 2.2 2 1 0 2 2 2 2 Signal peptidase subunit Macoilin PF09726.9 KKK13693.1 - 0.032 12.8 3.2 0.033 12.8 3.2 1.1 1 0 0 1 1 1 0 Macoilin family GGACT PF06094.12 KKK13694.1 - 9.3e-06 26.3 1.1 0.00012 22.6 1.1 2.0 1 1 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like Peptidase_C48 PF02902.19 KKK13695.1 - 3.2e-31 108.9 0.0 2e-30 106.3 0.0 2.1 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain IF4E PF01652.18 KKK13696.1 - 5.7e-55 185.5 0.0 1e-54 184.7 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E SelP_N PF04592.14 KKK13696.1 - 1.7 8.0 14.8 2.6 7.4 14.8 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Pkinase PF00069.25 KKK13697.1 - 2.6e-70 236.8 0.0 3.6e-70 236.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK13697.1 - 4.1e-34 118.0 0.0 6.6e-34 117.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KKK13697.1 - 0.00037 19.9 0.1 0.0016 17.8 0.0 1.8 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.14 KKK13697.1 - 0.015 14.7 0.4 0.027 13.8 0.4 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KKK13697.1 - 0.028 13.2 0.0 0.051 12.4 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 KKK13697.1 - 0.048 12.6 0.1 0.37 9.7 0.0 1.9 2 0 0 2 2 2 0 Haspin like kinase domain PLU-1 PF08429.11 KKK13698.1 - 4.3e-112 374.6 14.7 7e-109 364.1 13.2 2.2 2 0 0 2 2 2 2 PLU-1-like protein JmjC PF02373.22 KKK13698.1 - 2.5e-44 150.4 0.2 5.3e-44 149.3 0.2 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase ARID PF01388.21 KKK13698.1 - 1.6e-21 76.8 0.1 4.8e-21 75.2 0.1 1.9 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain PHD PF00628.29 KKK13698.1 - 2.9e-17 62.3 31.7 4.2e-10 39.4 7.3 3.5 3 0 0 3 3 3 2 PHD-finger zf-C5HC2 PF02928.16 KKK13698.1 - 4.8e-13 49.3 3.4 1.8e-12 47.4 3.4 2.1 1 0 0 1 1 1 1 C5HC2 zinc finger zf-PHD-like PF15446.6 KKK13698.1 - 0.015 14.9 9.6 0.071 12.7 1.1 2.8 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain DNApol3-delta_C PF09115.10 KKK13698.1 - 0.055 14.0 0.2 0.23 12.0 0.0 2.1 2 0 0 2 2 2 0 DNA polymerase III, delta subunit, C terminal Spore_III_AB PF09548.10 KKK13698.1 - 0.3 11.2 4.8 1.5 9.0 1.1 2.6 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) AEP1 PF17049.5 KKK13698.1 - 0.37 9.8 0.9 0.7 8.9 0.9 1.3 1 0 0 1 1 1 0 ATPase expression protein 1 PHD_4 PF16866.5 KKK13698.1 - 1.9 8.6 18.6 0.88 9.7 4.7 2.9 2 0 0 2 2 2 0 PHD-finger zf-RING_2 PF13639.6 KKK13698.1 - 2.7 8.4 24.9 3.5 8.0 8.8 2.9 2 0 0 2 2 2 0 Ring finger domain Zf_RING PF16744.5 KKK13698.1 - 5.2 7.3 20.3 2 8.6 6.2 3.5 3 0 0 3 3 3 0 KIAA1045 RING finger zf-rbx1 PF12678.7 KKK13698.1 - 6 7.2 18.0 0.74 10.1 5.5 3.0 2 0 0 2 2 2 0 RING-H2 zinc finger domain CAF1C_H4-bd PF12265.8 KKK13699.1 - 2.7e-28 98.0 1.1 1.2e-27 95.9 1.1 2.1 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 KKK13699.1 - 4e-27 93.9 7.6 0.00014 22.6 0.1 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKK13699.1 - 1.8e-06 28.2 0.8 0.29 11.4 0.0 4.9 2 1 4 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain DUF3751 PF12571.8 KKK13699.1 - 0.089 12.9 0.0 2.4 8.2 0.0 2.4 2 0 0 2 2 2 0 Phage tail-collar fibre protein Nup160 PF11715.8 KKK13699.1 - 0.099 11.3 2.5 7.8 5.0 0.1 3.8 1 1 1 3 3 3 0 Nucleoporin Nup120/160 GTP_cyclohydroI PF01227.22 KKK13700.1 - 1.7e-73 245.9 0.2 2.1e-73 245.6 0.2 1.1 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.6 KKK13700.1 - 0.0075 16.4 0.0 0.015 15.5 0.0 1.4 1 0 0 1 1 1 1 QueF-like protein NUDIX-like PF09296.11 KKK13701.1 - 7.5e-19 68.3 0.0 2e-18 66.9 0.0 1.7 2 0 0 2 2 2 1 NADH pyrophosphatase-like rudimentary NUDIX domain NUDIX PF00293.28 KKK13701.1 - 2.3e-17 63.3 0.1 4e-17 62.5 0.1 1.3 1 0 0 1 1 1 1 NUDIX domain DUF3991 PF13154.6 KKK13701.1 - 0.035 14.5 0.0 5.8 7.4 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3991) V-SNARE_C PF12352.8 KKK13701.1 - 0.05 13.9 0.0 0.1 12.9 0.0 1.5 1 0 0 1 1 1 0 Snare region anchored in the vesicle membrane C-terminus GDP_Man_Dehyd PF16363.5 KKK13701.1 - 0.056 12.8 0.0 0.085 12.2 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase CN_hydrolase PF00795.22 KKK13702.1 - 8.7e-43 146.5 0.0 1.3e-42 145.9 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.17 KKK13702.1 - 7e-21 74.4 0.0 3.6e-20 72.1 0.0 1.9 1 1 0 1 1 1 1 NAD synthase HDA2-3 PF11496.8 KKK13703.1 - 1e-57 195.6 0.0 2.1e-57 194.5 0.0 1.6 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 FMO-like PF00743.19 KKK13703.1 - 1.7e-37 129.1 0.0 2.5e-22 79.0 0.0 3.1 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KKK13703.1 - 6.1e-12 45.4 0.0 8.2e-09 35.1 0.0 3.7 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KKK13703.1 - 6.7e-11 42.0 0.0 2.1e-10 40.3 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KKK13703.1 - 4.8e-09 36.4 3.1 1.7e-06 28.1 0.1 4.7 3 2 1 4 4 4 1 FAD-NAD(P)-binding K_oxygenase PF13434.6 KKK13703.1 - 1.7e-07 30.7 2.5 1.5e-05 24.3 0.0 2.9 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KKK13703.1 - 5e-05 23.4 0.0 0.00014 22.0 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KKK13703.1 - 7.1e-05 22.5 2.3 1.2 8.7 0.0 4.1 5 0 0 5 5 5 2 FAD dependent oxidoreductase Thi4 PF01946.17 KKK13703.1 - 0.0002 20.7 0.0 0.0026 17.0 0.0 2.2 2 0 0 2 2 2 1 Thi4 family GAS PF13851.6 KKK13703.1 - 0.0036 16.7 33.1 0.014 14.7 7.6 2.5 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding Semialdhyde_dh PF01118.24 KKK13703.1 - 0.061 13.8 0.0 0.54 10.7 0.0 2.7 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain ArAE_2_N PF10337.9 KKK13703.1 - 0.68 8.9 3.6 1.3 8.0 3.6 1.4 1 0 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal Sec20 PF03908.13 KKK13703.1 - 4 7.4 7.2 14 5.7 2.9 3.0 1 1 1 2 2 2 0 Sec20 POT1 PF02765.17 KKK13704.1 - 6.3e-16 58.5 0.0 1.1e-15 57.8 0.0 1.4 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 Cu-oxidase_3 PF07732.15 KKK13705.1 - 1.1e-39 135.1 1.7 4.9e-39 133.0 1.7 2.1 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 KKK13705.1 - 1.4e-28 99.3 8.5 7.8e-23 80.7 0.2 3.8 3 2 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 KKK13705.1 - 1.2e-21 77.5 0.0 3.9e-19 69.3 0.0 2.8 2 1 0 2 2 2 2 Multicopper oxidase SAT PF16073.5 KKK13706.1 - 7e-84 281.3 4.1 2.5e-82 276.2 0.1 3.1 3 0 0 3 3 3 2 Starter unit:ACP transacylase in aflatoxin biosynthesis ketoacyl-synt PF00109.26 KKK13706.1 - 1.2e-81 274.0 0.0 9.5e-81 271.1 0.0 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 KKK13706.1 - 2.9e-48 165.0 1.4 6.8e-47 160.5 0.0 3.0 3 0 0 3 3 3 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KKK13706.1 - 8.9e-36 122.5 0.4 3.4e-35 120.6 0.4 2.1 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.25 KKK13706.1 - 2e-26 92.1 4.8 2.1e-13 50.4 0.5 2.6 2 0 0 2 2 2 2 Phosphopantetheine attachment site Thioesterase PF00975.20 KKK13706.1 - 1.8e-23 83.9 0.0 4.6e-23 82.5 0.0 1.7 1 0 0 1 1 1 1 Thioesterase domain PS-DH PF14765.6 KKK13706.1 - 1.3e-14 54.2 0.0 2.3e-14 53.3 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Abhydrolase_6 PF12697.7 KKK13706.1 - 5e-08 33.8 8.5 1.8e-07 32.0 0.9 3.4 3 0 0 3 3 3 1 Alpha/beta hydrolase family Thiolase_N PF00108.23 KKK13706.1 - 1.7e-05 24.4 0.0 8.5e-05 22.0 0.0 2.0 2 0 0 2 2 2 1 Thiolase, N-terminal domain KAsynt_C_assoc PF16197.5 KKK13706.1 - 5.3e-05 23.6 0.0 0.00014 22.3 0.0 1.8 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Transglut_core PF01841.19 KKK13708.1 - 1.1e-10 41.9 0.0 2.4e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily SH3_2 PF07653.17 KKK13708.1 - 9.2e-09 34.9 0.2 2.3e-08 33.6 0.1 1.8 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 KKK13708.1 - 2e-06 27.3 1.1 7.9e-06 25.4 0.0 2.3 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 KKK13708.1 - 0.0018 18.1 0.6 0.0066 16.3 0.1 2.1 2 0 0 2 2 2 1 Variant SH3 domain ERCC3_RAD25_C PF16203.5 KKK13709.1 - 2.9e-124 413.2 0.9 5.7e-124 412.2 0.9 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 KKK13709.1 - 1.3e-35 122.3 0.0 3e-35 121.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KKK13709.1 - 6.6e-15 55.5 0.0 1.4e-14 54.4 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KKK13709.1 - 1.5e-13 51.0 0.1 3.7e-13 49.8 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 KKK13709.1 - 2e-09 36.7 0.0 2.4e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.29 KKK13709.1 - 0.0003 20.6 0.0 0.00062 19.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_34 PF13872.6 KKK13709.1 - 0.00068 18.6 0.0 0.0012 17.8 0.0 1.3 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 DUF4677 PF15726.5 KKK13709.1 - 0.027 14.6 1.0 0.027 14.6 1.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4677) MPM1 PF17234.2 KKK13710.1 - 0.068 13.4 0.1 0.068 13.4 0.1 2.2 2 0 0 2 2 2 0 Mitochondrial peculiar membrane protein 1 BCDHK_Adom3 PF10436.9 KKK13711.1 - 6.4e-46 156.2 0.2 1.7e-45 154.8 0.0 1.7 2 0 0 2 2 2 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 KKK13711.1 - 3.5e-06 27.5 0.0 1.2e-05 25.8 0.0 1.8 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 KKK13711.1 - 0.071 13.1 0.0 1.6 8.7 0.0 2.3 2 0 0 2 2 2 0 Histidine kinase-like ATPase domain USP7_ICP0_bdg PF12436.8 KKK13712.1 - 1.3e-87 293.1 0.1 8.9e-87 290.4 0.1 2.1 2 0 0 2 2 2 1 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.6 KKK13712.1 - 2.6e-71 239.6 0.2 5.7e-69 231.9 0.0 3.2 2 1 0 3 3 3 1 Ubiquitin-specific protease C-terminal UCH PF00443.29 KKK13712.1 - 5e-48 163.8 0.2 1.1e-47 162.6 0.1 1.6 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KKK13712.1 - 9.6e-22 78.0 0.0 2.7e-21 76.5 0.0 1.8 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.26 KKK13712.1 - 8.8e-08 32.3 0.0 2.5e-07 30.8 0.0 1.9 1 0 0 1 1 1 1 MATH domain Rad60-SLD PF11976.8 KKK13712.1 - 0.01 15.6 0.6 9.6 6.1 0.1 4.0 3 1 0 3 3 3 0 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 KKK13712.1 - 0.017 14.9 0.9 14 5.6 0.0 4.0 4 0 0 4 4 4 0 Ubiquitin family Peptidase_C98 PF15499.6 KKK13712.1 - 0.23 10.9 1.0 0.56 9.6 0.1 2.1 2 0 0 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase EMP24_GP25L PF01105.24 KKK13713.1 - 4.7e-47 160.3 2.7 5.5e-47 160.1 2.7 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD IrmA PF18673.1 KKK13713.1 - 0.089 12.9 0.0 0.21 11.8 0.0 1.6 1 0 0 1 1 1 0 interleukin receptor mimic protein A Hydrophobin PF01185.18 KKK13715.1 - 0.00051 20.6 7.1 0.0011 19.6 7.1 1.6 1 0 0 1 1 1 1 Fungal hydrophobin CTD_bind PF04818.13 KKK13716.1 - 1.4e-11 45.0 0.1 3.8e-11 43.7 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase II-binding domain. DUF2457 PF10446.9 KKK13716.1 - 0.084 12.0 10.2 0.13 11.4 10.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) XRN_M PF17846.1 KKK13719.1 - 1.6e-99 333.9 3.1 2.6e-99 333.2 3.1 1.3 1 0 0 1 1 1 1 Xrn1 helical domain XRN_N PF03159.18 KKK13719.1 - 1.5e-96 322.5 0.0 1.5e-96 322.5 0.0 1.9 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus XRN1_D1 PF18332.1 KKK13719.1 - 9.9e-75 250.5 2.3 1e-74 250.5 0.0 2.0 2 0 0 2 2 2 1 Exoribonuclease Xrn1 D1 domain XRN1_D2_D3 PF18334.1 KKK13719.1 - 7.6e-31 106.2 0.4 2.1e-30 104.7 0.0 2.0 2 0 0 2 2 2 1 Exoribonuclease Xrn1 D2/D3 domain SH3_12 PF18129.1 KKK13719.1 - 4.2e-23 81.2 0.7 9.7e-23 80.1 0.7 1.7 1 0 0 1 1 1 1 Xrn1 SH3-like domain Xrn1_D3 PF18194.1 KKK13719.1 - 3.6e-06 27.0 0.2 9e-06 25.7 0.2 1.6 1 0 0 1 1 1 1 Exoribonuclease 1 Domain-3 p450 PF00067.22 KKK13720.1 - 1.2e-33 116.6 0.0 1.4e-33 116.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF4233 PF14017.6 KKK13720.1 - 4.2 7.8 5.2 0.87 10.0 1.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4233) Erg28 PF03694.13 KKK13739.1 - 1e-38 132.1 0.5 1.2e-38 131.9 0.5 1.1 1 0 0 1 1 1 1 Erg28 like protein adh_short PF00106.25 KKK13740.1 - 2.5e-37 128.2 0.0 3.8e-37 127.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KKK13740.1 - 4e-24 85.5 0.0 5.2e-24 85.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KKK13740.1 - 0.00021 21.2 0.0 0.0004 20.4 0.0 1.5 1 1 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 KKK13740.1 - 0.046 13.6 0.0 0.065 13.1 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Acetyltransf_1 PF00583.25 KKK13741.1 - 3.8e-14 52.9 0.0 8.4e-14 51.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KKK13741.1 - 9.2e-13 48.3 0.0 1.3e-12 47.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KKK13741.1 - 2.8e-08 34.0 0.0 5.1e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KKK13741.1 - 0.0036 17.4 0.3 0.013 15.6 0.0 2.0 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KKK13741.1 - 0.0096 16.0 0.1 0.021 14.9 0.1 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.10 KKK13741.1 - 0.2 11.6 0.0 0.36 10.8 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein NAT PF04768.13 KKK13742.1 - 2.7e-52 176.9 0.0 3.2e-51 173.3 0.0 2.3 2 0 0 2 2 2 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase Sugar_tr PF00083.24 KKK13743.1 - 7.2e-136 453.6 29.4 8.3e-136 453.4 29.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKK13743.1 - 9.5e-22 77.4 60.0 2e-19 69.8 33.1 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2530 PF10745.9 KKK13743.1 - 0.023 14.9 2.6 0.023 14.9 2.6 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF2530) NOG1_N PF17835.1 KKK13744.1 - 1.1e-49 168.5 0.8 1.7e-49 167.9 0.0 1.8 2 0 0 2 2 2 1 NOG1 N-terminal helical domain NOGCT PF08155.11 KKK13744.1 - 4.3e-28 97.1 4.8 1e-27 95.8 4.8 1.7 1 0 0 1 1 1 1 NOGCT (NUC087) domain NOG1 PF06858.14 KKK13744.1 - 2.5e-26 91.2 0.2 5.7e-26 90.1 0.2 1.7 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.23 KKK13744.1 - 8.6e-16 58.0 0.0 2.2e-15 56.7 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KKK13744.1 - 1e-07 31.6 0.0 2.4e-07 30.4 0.0 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 KKK13744.1 - 0.013 15.5 0.0 9 6.3 0.0 2.8 1 1 0 2 2 2 0 Dynamin family RsgA_GTPase PF03193.16 KKK13744.1 - 0.02 14.8 0.1 6.8 6.6 0.1 2.9 2 1 0 2 2 2 0 RsgA GTPase AAA_16 PF13191.6 KKK13744.1 - 0.021 15.2 0.1 0.2 12.0 0.0 2.6 3 0 0 3 3 3 0 AAA ATPase domain AAA_23 PF13476.6 KKK13744.1 - 0.046 14.2 0.1 2.3 8.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain EIF_2_alpha PF07541.12 KKK13744.1 - 0.062 13.4 0.0 0.15 12.1 0.0 1.7 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 2 alpha subunit Sigma54_activ_2 PF14532.6 KKK13744.1 - 0.16 12.1 0.1 0.39 10.8 0.1 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain BAR_2 PF10455.9 KKK13745.1 - 8.1e-62 209.0 0.9 1.2e-61 208.4 0.9 1.2 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.18 KKK13745.1 - 2.7e-20 73.1 6.5 9.2e-19 68.0 6.5 2.0 1 1 0 1 1 1 1 BAR domain BAR_3 PF16746.5 KKK13745.1 - 0.0048 16.6 1.3 0.018 14.7 0.1 2.1 2 0 0 2 2 2 1 BAR domain of APPL family DUF4111 PF13427.6 KKK13745.1 - 0.0078 16.4 0.0 0.027 14.6 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4111) DUF4472 PF14739.6 KKK13745.1 - 0.66 10.7 5.9 1.4 9.7 0.4 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4472) Arv1 PF04161.13 KKK13747.1 - 2e-60 204.6 0.0 1.4e-59 201.8 0.0 2.0 1 1 0 1 1 1 1 Arv1-like family ATP_synt_H PF05493.13 KKK13748.1 - 0.00011 22.6 0.2 0.00011 22.5 0.2 1.0 1 0 0 1 1 1 1 ATP synthase subunit H PsbX PF06596.11 KKK13748.1 - 0.018 15.0 1.7 0.019 14.9 1.7 1.1 1 0 0 1 1 1 0 Photosystem II reaction centre X protein (PsbX) Ureide_permease PF07168.11 KKK13748.1 - 0.09 11.5 0.0 0.09 11.5 0.0 1.0 1 0 0 1 1 1 0 Ureide permease Phage_holin_2_3 PF16080.5 KKK13748.1 - 0.1 12.4 0.6 0.11 12.3 0.6 1.0 1 0 0 1 1 1 0 Bacteriophage holin family HP1 DUF4748 PF15932.5 KKK13748.1 - 0.11 12.3 0.3 0.11 12.3 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4748) FeoB_associated PF12669.7 KKK13748.1 - 0.11 12.9 0.4 0.12 12.8 0.4 1.1 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein AMP-binding PF00501.28 KKK13749.1 - 6.1e-55 186.5 0.0 8.4e-55 186.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KKK13749.1 - 0.00083 20.3 0.1 0.0018 19.2 0.1 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ATG22 PF11700.8 KKK13750.1 - 3.4e-135 451.4 25.9 4e-135 451.1 25.9 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.16 KKK13750.1 - 3e-12 46.1 25.3 9e-08 31.4 10.6 3.2 2 1 1 3 3 3 3 Major Facilitator Superfamily Proton_antipo_N PF00662.20 KKK13750.1 - 0.25 11.4 3.6 0.27 11.3 0.2 2.8 2 0 0 2 2 2 0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus DUF2678 PF10856.8 KKK13750.1 - 2.2 8.2 7.6 0.86 9.6 0.5 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF2678) Thiolase_N PF00108.23 KKK13751.1 - 3.5e-64 216.7 1.1 6.4e-64 215.8 1.1 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KKK13751.1 - 2e-39 134.0 0.1 4.2e-39 133.0 0.1 1.5 1 0 0 1 1 1 1 Thiolase, C-terminal domain HNH_2 PF13391.6 KKK13751.1 - 8.3e-12 45.1 0.3 1.8e-11 44.0 0.3 1.6 1 0 0 1 1 1 1 HNH endonuclease ketoacyl-synt PF00109.26 KKK13751.1 - 0.0025 17.4 1.2 0.01 15.4 1.1 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 KKK13751.1 - 0.011 15.6 0.8 0.41 10.5 0.2 2.4 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GCP_N_terminal PF17681.1 KKK13752.1 - 1.4e-66 225.3 0.0 2.1e-66 224.6 0.0 1.3 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 KKK13752.1 - 3.5e-62 210.6 2.6 7.1e-62 209.6 2.6 1.5 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal CLZ PF16526.5 KKK13752.1 - 0.33 11.3 3.8 0.35 11.3 0.3 2.8 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Proteasome PF00227.26 KKK13753.1 - 9.4e-57 191.6 0.0 1.2e-56 191.3 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KKK13753.1 - 1.5e-12 47.0 0.2 3.6e-12 45.7 0.0 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature KH_8 PF17903.1 KKK13754.1 - 2.1e-31 107.8 0.0 5.3e-31 106.6 0.0 1.7 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 KKK13754.1 - 0.012 15.4 0.1 0.037 13.8 0.0 2.0 2 0 0 2 2 2 0 KH domain Methyltransf_11 PF08241.12 KKK13755.1 - 1.9e-10 41.3 0.0 3.3e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KKK13755.1 - 2.4e-10 40.5 0.0 3.6e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKK13755.1 - 2e-09 38.0 0.0 7.1e-09 36.3 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KKK13755.1 - 6.3e-07 30.1 0.0 1.8e-06 28.6 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KKK13755.1 - 1.7e-06 27.9 0.4 3.5e-05 23.7 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.17 KKK13755.1 - 3.6e-05 23.3 0.0 0.0002 20.9 0.0 2.0 2 0 0 2 2 2 1 Putative methyltransferase Ubie_methyltran PF01209.18 KKK13755.1 - 0.008 15.5 0.0 0.094 12.0 0.0 2.1 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family FtsJ PF01728.19 KKK13755.1 - 0.016 15.3 0.0 0.045 13.9 0.0 1.7 2 0 0 2 2 2 0 FtsJ-like methyltransferase Methyltransf_8 PF05148.15 KKK13755.1 - 0.11 12.4 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Hypothetical methyltransferase Methyltransf_2 PF00891.18 KKK13755.1 - 0.16 11.3 0.0 1.3 8.3 0.0 2.0 2 0 0 2 2 2 0 O-methyltransferase domain Methyltransf_8 PF05148.15 KKK13756.1 - 1.8e-53 181.7 0.0 2.5e-51 174.6 0.0 2.6 3 0 0 3 3 3 1 Hypothetical methyltransferase Methyltransf_11 PF08241.12 KKK13756.1 - 2.1e-07 31.5 0.0 1.2e-06 29.1 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKK13756.1 - 5e-06 27.1 0.0 0.00034 21.2 0.0 2.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 KKK13756.1 - 0.016 15.2 0.0 0.016 15.2 0.0 3.2 3 1 0 3 3 3 0 Methyltransferase domain Methyltransf_31 PF13847.6 KKK13756.1 - 0.021 14.6 0.1 2.1 8.1 0.1 2.5 1 1 0 1 1 1 0 Methyltransferase domain Fungal_trans_2 PF11951.8 KKK13757.1 - 2.5e-18 66.1 0.6 5.4e-14 51.8 0.1 3.1 3 0 0 3 3 3 3 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK13757.1 - 4.5e-07 29.9 11.5 4.5e-07 29.9 11.5 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KKK13757.1 - 0.09 11.8 0.4 0.18 10.8 0.4 1.5 1 1 0 1 1 1 0 Fungal specific transcription factor domain GalP_UDP_transf PF01087.22 KKK13758.1 - 2e-69 233.7 0.0 1.1e-67 228.0 0.0 2.3 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.17 KKK13758.1 - 4.1e-58 195.8 0.3 1.1e-57 194.4 0.3 1.6 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, C-terminal domain DUF4921 PF16268.5 KKK13758.1 - 0.0029 16.5 0.1 0.28 9.9 0.0 2.6 2 1 0 3 3 3 2 Domain of unknown function (DUF4921) UDPGT PF00201.18 KKK13759.1 - 4.3e-08 32.4 0.0 7.8e-08 31.5 0.0 1.4 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase F-box-like PF12937.7 KKK13759.1 - 1.9e-06 27.6 0.4 4.3e-06 26.5 0.4 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KKK13759.1 - 0.01 15.7 0.5 0.021 14.7 0.5 1.5 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 KKK13759.1 - 0.017 15.0 0.2 0.033 14.1 0.2 1.4 1 0 0 1 1 1 0 F-box PRK PF00485.18 KKK13759.1 - 0.23 11.2 0.0 0.41 10.3 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family NAD_binding_2 PF03446.15 KKK13760.1 - 8.4e-10 39.0 3.4 6.1e-05 23.2 0.3 3.3 1 1 1 2 2 2 2 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 KKK13760.1 - 1.4e-09 38.2 0.0 2.6e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase SAP PF02037.27 KKK13764.1 - 2.5e-12 46.2 0.6 6.3e-11 41.8 0.0 2.3 2 0 0 2 2 2 1 SAP domain Tho1_MOS11_C PF18592.1 KKK13764.1 - 1.1e-10 41.1 9.4 8.4e-08 31.9 4.1 2.5 2 1 1 3 3 3 2 Tho1/MOS11 C-terminal domain Methyltransf_11 PF08241.12 KKK13765.1 - 0.00018 22.1 0.0 0.0006 20.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKK13765.1 - 0.091 13.5 0.0 0.19 12.4 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain GST_N_3 PF13417.6 KKK13780.1 - 6.3e-12 45.7 0.0 1.2e-11 44.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KKK13780.1 - 1.6e-10 41.1 0.0 4e-10 39.9 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KKK13780.1 - 3.5e-10 40.0 0.1 7.1e-10 39.0 0.1 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KKK13780.1 - 6.1e-09 36.0 0.0 9.4e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KKK13780.1 - 5e-07 29.7 0.4 1.2e-06 28.4 0.3 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KKK13780.1 - 6.8e-06 26.3 0.0 2.2e-05 24.6 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_5 PF16865.5 KKK13780.1 - 0.0094 16.5 0.0 0.065 13.8 0.0 2.1 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 KKK13780.1 - 0.097 13.4 0.0 0.35 11.6 0.0 2.0 1 1 0 1 1 1 0 Glutathione S-transferase N-terminal domain APH PF01636.23 KKK13781.1 - 3.9e-13 49.9 0.0 2.2e-12 47.4 0.0 2.2 1 1 0 1 1 1 1 Phosphotransferase enzyme family Acetyltransf_3 PF13302.7 KKK13782.1 - 2.3e-13 51.0 0.0 3.1e-13 50.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KKK13782.1 - 2.1e-10 40.9 0.0 3.6e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KKK13782.1 - 0.00034 21.0 0.0 0.00051 20.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KKK13782.1 - 0.0014 18.8 0.0 0.0022 18.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 KKK13782.1 - 0.0049 16.5 0.0 0.0097 15.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KKK13782.1 - 0.012 15.5 0.0 0.032 14.2 0.0 1.6 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain AA_permease_2 PF13520.6 KKK13785.1 - 1.6e-36 126.1 46.9 1.9e-36 125.8 46.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KKK13785.1 - 3.9e-15 55.4 38.0 5e-15 55.1 38.0 1.1 1 0 0 1 1 1 1 Amino acid permease DSBA PF01323.20 KKK13786.1 - 5.7e-13 49.1 0.0 9e-13 48.4 0.0 1.3 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Abhydrolase_6 PF12697.7 KKK13786.1 - 1.6e-11 45.2 0.2 4e-11 43.9 0.1 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KKK13786.1 - 2.6e-05 23.6 0.0 7.3e-05 22.1 0.0 1.7 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KKK13786.1 - 0.00026 20.7 0.2 0.00051 19.8 0.2 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Agglutinin PF07468.11 KKK13787.1 - 0.2 11.9 0.0 0.27 11.4 0.0 1.1 1 0 0 1 1 1 0 Agglutinin domain Peptidase_S15 PF02129.18 KKK13788.1 - 5.9e-39 134.3 0.4 8.4e-37 127.2 0.2 2.1 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.10 KKK13788.1 - 1.4e-13 51.3 0.0 4.4e-13 49.7 0.0 1.7 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Hydrolase_4 PF12146.8 KKK13788.1 - 0.03 13.6 0.2 0.051 12.8 0.2 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 GST_N_3 PF13417.6 KKK13789.1 - 3.7e-15 56.1 0.0 6.2e-15 55.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KKK13789.1 - 6.9e-15 55.1 0.0 1.2e-14 54.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KKK13789.1 - 4.6e-13 49.3 0.1 1.8e-12 47.4 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.24 KKK13789.1 - 0.00014 22.0 0.0 0.00022 21.4 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin p450 PF00067.22 KKK13791.1 - 4.6e-57 193.8 0.0 6.8e-57 193.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.18 KKK13792.1 - 7.2e-14 51.5 0.0 4.2e-13 49.0 0.0 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK13792.1 - 4e-07 30.0 15.5 9.1e-07 28.9 15.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldo_ket_red PF00248.21 KKK13793.1 - 2.5e-53 181.2 0.0 3.2e-53 180.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family GMC_oxred_N PF00732.19 KKK13794.1 - 4e-79 266.1 0.0 5.8e-79 265.5 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KKK13794.1 - 8.9e-35 120.3 0.0 2.1e-34 119.1 0.0 1.6 1 1 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KKK13794.1 - 1.1e-06 28.0 0.3 0.016 14.3 0.2 2.2 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 KKK13794.1 - 6.3e-05 22.2 0.1 0.0001 21.5 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KKK13794.1 - 0.0017 17.6 0.0 0.0041 16.4 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KKK13794.1 - 0.0028 16.8 0.1 0.038 13.1 0.1 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A DAO PF01266.24 KKK13794.1 - 0.0079 15.8 2.5 0.058 13.0 1.5 2.5 2 1 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 KKK13794.1 - 0.023 13.9 0.3 0.13 11.5 0.1 1.9 2 0 0 2 2 2 0 Thi4 family FAD_oxidored PF12831.7 KKK13794.1 - 0.046 13.1 0.6 0.1 11.9 0.6 1.6 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KKK13794.1 - 0.05 13.8 0.4 0.12 12.6 0.4 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KKK13794.1 - 0.094 11.4 0.3 0.2 10.3 0.2 1.6 2 0 0 2 2 2 0 HI0933-like protein Trp_halogenase PF04820.14 KKK13794.1 - 0.15 10.9 0.1 0.23 10.2 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase DASH_Dam1 PF08653.10 KKK13801.1 - 2.2e-29 101.0 2.3 2.9e-29 100.6 2.3 1.2 1 0 0 1 1 1 1 DASH complex subunit Dam1 Ribosomal_60s PF00428.19 KKK13801.1 - 0.026 15.1 0.1 0.042 14.4 0.1 1.2 1 0 0 1 1 1 0 60s Acidic ribosomal protein UCH PF00443.29 KKK13802.1 - 3e-47 161.3 0.0 4e-47 160.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KKK13802.1 - 9.7e-19 68.1 0.0 9.9e-18 64.8 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 KKK13802.1 - 0.00015 22.0 1.5 0.00037 20.8 0.3 2.4 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein zf-LYAR PF08790.11 KKK13802.1 - 0.045 13.7 0.1 0.18 11.8 0.1 2.2 1 0 0 1 1 1 0 LYAR-type C2HC zinc finger Nitroreductase PF00881.24 KKK13803.1 - 4.4e-16 59.4 0.0 5.5e-16 59.1 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family Ribosomal_S14 PF00253.21 KKK13804.1 - 0.00036 20.2 0.1 0.00038 20.1 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e HIT PF01230.23 KKK13805.1 - 1.8e-22 79.9 0.2 2.4e-22 79.5 0.2 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 KKK13805.1 - 3.6e-13 50.0 0.0 5.3e-13 49.4 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 KKK13805.1 - 3.8e-05 23.5 0.0 5.3e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CRAL_TRIO PF00650.20 KKK13806.1 - 4.7e-43 146.7 0.1 8.3e-43 145.9 0.1 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KKK13806.1 - 8.3e-15 54.7 0.2 3e-14 52.9 0.2 2.0 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 KKK13806.1 - 4.3e-05 23.7 0.0 7.2e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain DUF4570 PF15134.6 KKK13806.1 - 0.82 9.7 6.5 0.98 9.5 4.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4570) Peptidase_M20 PF01546.28 KKK13807.1 - 0.023 14.4 0.0 0.033 13.9 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 Cullin PF00888.22 KKK13808.1 - 5.7e-180 600.0 0.0 7e-180 599.7 0.0 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 KKK13808.1 - 7.9e-24 83.5 1.2 1.8e-23 82.3 1.2 1.7 1 0 0 1 1 1 1 Cullin protein neddylation domain HTH_38 PF13936.6 KKK13808.1 - 0.036 13.8 0.0 0.11 12.2 0.0 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain HbrB PF08539.11 KKK13808.1 - 0.093 12.7 0.0 0.39 10.7 0.0 2.0 1 1 0 1 1 1 0 HbrB-like QSOX_Trx1 PF18108.1 KKK13808.1 - 0.12 12.6 0.1 0.44 10.8 0.1 2.0 1 0 0 1 1 1 0 QSOX Trx-like domain Nup192 PF11894.8 KKK13809.1 - 0 1408.5 9.0 0 1408.3 9.0 1.0 1 0 0 1 1 1 1 Nuclear pore complex scaffold, nucleoporins 186/192/205 DCB PF16213.5 KKK13809.1 - 0.017 14.8 2.9 0.2 11.3 1.3 3.3 3 1 0 3 3 3 0 Dimerisation and cyclophilin-binding domain of Mon2 Hormone_3 PF00159.18 KKK13809.1 - 0.11 12.6 0.0 23 5.1 0.0 2.7 2 0 0 2 2 2 0 Pancreatic hormone peptide UPF0052 PF01933.18 KKK13810.1 - 1.6e-60 204.8 0.0 2.1e-60 204.4 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 PI3_PI4_kinase PF00454.27 KKK13811.1 - 9.6e-52 176.3 0.5 2.8e-51 174.7 0.0 1.9 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase TAN PF11640.8 KKK13811.1 - 6.1e-50 169.3 1.7 4e-49 166.6 1.7 2.6 1 0 0 1 1 1 1 Telomere-length maintenance and DNA damage repair FATC PF02260.20 KKK13811.1 - 1.3e-12 47.3 1.0 1.8e-10 40.4 0.1 3.5 3 0 0 3 3 3 1 FATC domain FAT PF02259.23 KKK13811.1 - 1e-05 25.0 4.7 2.4e-05 23.7 4.7 1.6 1 0 0 1 1 1 1 FAT domain SQS_PSY PF00494.19 KKK13812.1 - 7.7e-50 169.8 1.7 1.2e-49 169.2 1.7 1.2 1 0 0 1 1 1 1 Squalene/phytoene synthase CorA PF01544.18 KKK13813.1 - 4.5e-26 91.8 9.2 2.3e-18 66.5 1.4 3.2 3 0 0 3 3 3 3 CorA-like Mg2+ transporter protein DUF1003 PF06210.11 KKK13813.1 - 0.023 14.8 1.5 0.25 11.5 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1003) DUF1143 PF06608.11 KKK13813.1 - 0.16 12.0 0.2 0.28 11.2 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1143) DNApol_Exo PF18136.1 KKK13815.1 - 9.2e-106 353.1 0.1 1.5e-105 352.4 0.1 1.3 1 0 0 1 1 1 1 DNA mitochondrial polymerase exonuclease domain DNA_pol_A PF00476.20 KKK13815.1 - 7.1e-58 196.5 0.0 1.1e-57 195.8 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family A Mad3_BUB1_I PF08311.12 KKK13815.1 - 0.011 15.7 0.6 0.028 14.4 0.6 1.6 1 0 0 1 1 1 0 Mad3/BUB1 homology region 1 DNA_pol_A_exo1 PF01612.20 KKK13815.1 - 0.096 12.4 0.3 1.1 8.9 0.3 2.6 1 1 0 1 1 1 0 3'-5' exonuclease SNF2_N PF00176.23 KKK13816.1 - 2.2e-70 237.1 0.0 3e-70 236.7 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.11 KKK13816.1 - 1.2e-23 82.9 0.0 2.1e-23 82.1 0.0 1.4 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.31 KKK13816.1 - 3.3e-14 53.2 0.0 8e-14 51.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.6 KKK13816.1 - 0.00027 20.7 4.6 0.0006 19.6 4.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KKK13816.1 - 0.00045 20.0 8.1 0.00082 19.2 8.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KKK13816.1 - 0.00051 19.8 4.7 0.00093 19.0 4.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.15 KKK13816.1 - 0.00073 19.6 0.0 0.0017 18.4 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-RING_UBOX PF13445.6 KKK13816.1 - 0.00094 19.2 7.9 0.002 18.1 7.9 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 KKK13816.1 - 0.0014 18.9 8.2 0.003 17.8 8.2 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 KKK13816.1 - 0.0037 17.2 6.2 0.0072 16.3 6.2 1.5 1 0 0 1 1 1 1 zinc-RING finger domain UBA_4 PF14555.6 KKK13816.1 - 0.065 13.1 0.0 0.17 11.7 0.0 1.7 1 0 0 1 1 1 0 UBA-like domain zf-C3HC4_4 PF15227.6 KKK13816.1 - 0.21 11.8 7.9 0.39 10.9 7.9 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 KKK13816.1 - 1.4 8.9 7.9 6.4 6.7 7.9 2.0 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 KKK13816.1 - 5.4 7.2 6.6 2.5 8.3 3.9 1.8 2 0 0 2 2 2 0 zinc RING finger of MSL2 Cut12 PF11500.8 KKK13817.1 - 2.6e-46 157.1 16.5 2.6e-46 157.1 16.5 4.4 3 1 1 4 4 4 1 Spindle pole body formation-associated protein HECW1_helix PF18436.1 KKK13817.1 - 0.15 12.2 0.1 0.51 10.5 0.1 1.9 1 0 0 1 1 1 0 Helical box domain of E3 ubiquitin-protein ligase HECW1 DUF2399 PF09664.10 KKK13817.1 - 0.5 10.3 3.8 1.7 8.5 2.1 2.6 2 0 0 2 2 2 0 Protein of unknown function C-terminus (DUF2399) Baculo_F PF12259.8 KKK13817.1 - 2.2 6.7 9.5 3.9 5.9 9.5 1.3 1 0 0 1 1 1 0 Baculovirus F protein Band_7 PF01145.25 KKK13817.1 - 8.5 6.3 13.5 4.3 7.3 5.8 2.5 2 0 0 2 2 2 0 SPFH domain / Band 7 family Pkinase PF00069.25 KKK13818.1 - 3.7e-31 108.5 0.0 7.4e-15 55.0 0.0 3.6 3 1 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 KKK13818.1 - 1.2e-20 73.8 0.0 8.1e-13 48.2 0.0 2.8 2 1 0 2 2 2 2 Protein tyrosine kinase RWD PF05773.22 KKK13818.1 - 4.2e-19 68.9 0.0 8.5e-19 67.9 0.0 1.5 1 0 0 1 1 1 1 RWD domain DUF1682 PF07946.14 KKK13818.1 - 0.16 11.1 6.8 0.23 10.6 6.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) GCIP PF13324.6 KKK13818.1 - 0.4 10.3 3.3 1.9 8.0 3.7 1.8 2 0 0 2 2 2 0 Grap2 and cyclin-D-interacting XRN_M PF17846.1 KKK13818.1 - 2.2 7.1 5.5 6 5.7 0.0 2.1 2 0 0 2 2 2 0 Xrn1 helical domain Aminotran_3 PF00202.21 KKK13819.1 - 3.5e-119 398.1 0.0 4.1e-119 397.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Spt4 PF06093.13 KKK13820.1 - 2.8e-32 110.6 0.1 3.4e-32 110.4 0.1 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger NmrA PF05368.13 KKK13821.1 - 8.6e-34 117.1 0.0 1.2e-33 116.6 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KKK13821.1 - 6.2e-09 36.0 0.3 9.4e-09 35.4 0.3 1.2 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KKK13821.1 - 0.0095 15.0 0.0 0.016 14.2 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.18 KKK13821.1 - 0.035 14.3 0.0 0.059 13.6 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain p450 PF00067.22 KKK13822.1 - 2e-24 86.2 0.0 3.5e-24 85.4 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 adh_short_C2 PF13561.6 KKK13823.1 - 7.5e-27 94.4 0.4 9.3e-27 94.1 0.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KKK13823.1 - 1.6e-18 66.9 0.1 2.1e-18 66.5 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KKK13823.1 - 6.3e-06 26.2 0.0 8.8e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_7 PF13241.6 KKK13823.1 - 0.0023 18.4 0.1 0.0072 16.8 0.0 1.8 2 0 0 2 2 2 1 Putative NAD(P)-binding THF_DHG_CYH_C PF02882.19 KKK13823.1 - 0.029 13.7 0.2 0.13 11.6 0.0 2.0 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.21 KKK13823.1 - 0.086 12.3 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family FAD_binding_3 PF01494.19 KKK13824.1 - 4.7e-17 62.3 1.0 3.8e-16 59.3 0.7 2.4 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KKK13824.1 - 1e-07 31.9 3.7 0.00089 18.9 0.1 2.8 1 1 1 3 3 3 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KKK13824.1 - 3.1e-06 26.6 0.4 5.6e-06 25.7 0.4 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KKK13824.1 - 0.00018 20.9 0.1 0.013 14.8 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KKK13824.1 - 0.0021 16.9 0.2 0.0083 14.9 0.3 1.7 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.6 KKK13824.1 - 0.0035 17.5 0.3 0.01 16.1 0.3 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 KKK13824.1 - 0.012 14.7 0.2 0.017 14.2 0.2 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A FAD_oxidored PF12831.7 KKK13824.1 - 0.013 14.9 0.2 0.019 14.4 0.2 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KKK13824.1 - 0.18 11.0 0.2 1.2 8.3 0.4 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NmrA PF05368.13 KKK13825.1 - 3.7e-28 98.7 0.0 2e-25 89.8 0.0 2.1 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KKK13825.1 - 6.7e-11 42.4 0.1 9.2e-11 42.0 0.1 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 KKK13825.1 - 0.00012 22.4 0.0 0.00023 21.4 0.0 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain PALP PF00291.25 KKK13825.1 - 0.0017 17.8 0.1 0.0029 17.1 0.1 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Epimerase PF01370.21 KKK13825.1 - 0.033 13.7 0.1 0.054 12.9 0.1 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family KR PF08659.10 KKK13825.1 - 0.087 12.7 0.2 0.14 12.0 0.2 1.3 1 0 0 1 1 1 0 KR domain DapB_N PF01113.20 KKK13825.1 - 0.14 12.3 0.2 0.23 11.6 0.2 1.3 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.24 KKK13825.1 - 0.16 12.4 0.1 0.33 11.4 0.1 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain p450 PF00067.22 KKK13826.1 - 1.1e-41 143.1 0.0 1.5e-41 142.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 MBOAT_2 PF13813.6 KKK13827.1 - 4.3e-21 75.0 2.5 9.3e-21 73.9 2.5 1.6 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family SPASM PF13186.6 KKK13827.1 - 0.2 12.2 0.0 0.52 10.9 0.0 1.7 1 0 0 1 1 1 0 Iron-sulfur cluster-binding domain NmrA PF05368.13 KKK13828.1 - 1.2e-34 119.8 0.0 1.8e-34 119.4 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KKK13828.1 - 7e-12 45.6 0.5 1e-11 45.1 0.5 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 KKK13828.1 - 2.2e-06 28.0 0.1 3.6e-06 27.3 0.1 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 KKK13828.1 - 0.0017 18.8 0.1 0.0051 17.2 0.0 1.8 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.21 KKK13828.1 - 0.011 15.2 0.1 0.021 14.3 0.1 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DapB_N PF01113.20 KKK13828.1 - 0.053 13.6 0.1 0.099 12.8 0.1 1.5 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Methyltransf_25 PF13649.6 KKK13828.1 - 0.067 13.9 0.0 2.6 8.8 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain TrkA_N PF02254.18 KKK13828.1 - 0.092 13.0 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain DUF4777 PF16007.5 KKK13828.1 - 0.093 13.0 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4777) KR PF08659.10 KKK13828.1 - 0.098 12.6 0.3 0.16 11.9 0.3 1.4 1 1 0 1 1 1 0 KR domain Trp_DMAT PF11991.8 KKK13829.1 - 5.7e-94 315.5 0.0 6.9e-94 315.2 0.0 1.1 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase NmrA PF05368.13 KKK13830.1 - 1.4e-30 106.6 0.0 1.8e-30 106.3 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KKK13830.1 - 6e-14 52.4 0.0 9e-14 51.8 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KKK13830.1 - 0.00032 19.8 0.0 0.00049 19.2 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KKK13830.1 - 0.00075 19.0 0.0 0.0012 18.3 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 KKK13830.1 - 0.0027 17.9 0.0 0.0068 16.7 0.0 1.6 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain F420_oxidored PF03807.17 KKK13830.1 - 0.0036 17.8 0.0 0.022 15.3 0.0 2.3 3 0 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.18 KKK13830.1 - 0.0095 16.2 0.1 0.02 15.1 0.0 1.6 2 0 0 2 2 2 1 TrkA-N domain GAD-like PF08887.11 KKK13830.1 - 0.066 13.0 0.2 0.17 11.7 0.2 1.6 1 0 0 1 1 1 0 GAD-like domain Methyltransf_31 PF13847.6 KKK13831.1 - 2.6e-10 40.3 0.0 6.8e-10 38.9 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKK13831.1 - 1e-09 39.0 0.2 3.2e-09 37.4 0.1 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KKK13831.1 - 1.6e-06 28.7 0.1 6.7e-06 26.8 0.1 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KKK13831.1 - 5.3e-06 26.4 0.0 1.4e-05 25.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KKK13831.1 - 3e-05 24.6 0.1 0.00012 22.6 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain CheR PF01739.18 KKK13831.1 - 0.00045 19.7 0.0 0.00066 19.2 0.0 1.2 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain Methyltransf_4 PF02390.17 KKK13831.1 - 0.019 14.4 0.0 0.03 13.8 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Ubie_methyltran PF01209.18 KKK13831.1 - 0.058 12.7 0.0 0.092 12.1 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family p450 PF00067.22 KKK13832.1 - 2.1e-65 221.3 0.0 2.6e-65 221.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Trp_DMAT PF11991.8 KKK13833.1 - 2.5e-90 303.5 0.0 3e-90 303.3 0.0 1.1 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase PhyH PF05721.13 KKK13834.1 - 8.7e-23 81.7 0.0 1.2e-22 81.2 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.12 KKK13834.1 - 1.2e-06 27.6 0.1 3.9e-06 25.9 0.0 1.8 2 1 0 2 2 2 1 Protein of unknown function (DUF1479) p450 PF00067.22 KKK13835.1 - 3.5e-42 144.7 0.0 8.6e-42 143.4 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 AMP-binding PF00501.28 KKK13836.1 - 4.1e-139 463.8 0.1 1.4e-71 241.4 0.0 2.5 2 0 0 2 2 2 2 AMP-binding enzyme NAD_binding_4 PF07993.12 KKK13836.1 - 1.9e-39 135.4 0.0 4.1e-39 134.3 0.0 1.6 1 1 0 1 1 1 1 Male sterility protein Condensation PF00668.20 KKK13836.1 - 6.9e-36 123.9 0.0 4.5e-35 121.2 0.0 2.3 2 1 0 2 2 2 1 Condensation domain PP-binding PF00550.25 KKK13836.1 - 8.9e-16 58.0 2.6 8.3e-08 32.5 0.2 3.1 3 0 0 3 3 3 2 Phosphopantetheine attachment site Epimerase PF01370.21 KKK13836.1 - 9.4e-07 28.5 0.0 8.2e-06 25.4 0.0 2.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KKK13836.1 - 0.01 15.0 0.0 4.4 6.4 0.0 2.4 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein AMP-binding_C PF13193.6 KKK13836.1 - 0.14 13.1 0.0 6.3 7.9 0.0 3.0 2 0 0 2 2 2 0 AMP-binding enzyme C-terminal domain 3Beta_HSD PF01073.19 KKK13836.1 - 0.14 11.1 0.0 0.33 9.9 0.0 1.6 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family FAD_binding_4 PF01565.23 KKK13837.1 - 2.7e-20 72.5 2.3 6.9e-20 71.2 2.3 1.7 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KKK13837.1 - 1.3e-05 25.2 0.0 2.6e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like PhyH PF05721.13 KKK13838.1 - 6.8e-21 75.5 0.1 1.2e-20 74.6 0.1 1.4 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.12 KKK13838.1 - 0.00046 19.1 0.0 0.0014 17.4 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1479) DUF89 PF01937.19 KKK13839.1 - 2.8e-138 460.7 0.0 3.2e-138 460.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 PPP5 PF08321.12 KKK13840.1 - 9e-34 115.6 0.2 2.1e-33 114.4 0.2 1.7 1 0 0 1 1 1 1 PPP5 TPR repeat region Metallophos PF00149.28 KKK13840.1 - 5.4e-31 108.7 0.0 7.8e-31 108.2 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase TPR_1 PF00515.28 KKK13840.1 - 1.2e-10 40.7 4.6 0.00023 20.9 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 KKK13840.1 - 5.6e-09 35.4 6.6 0.0062 16.6 0.1 3.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 KKK13840.1 - 1.5e-05 24.6 1.7 0.46 10.2 0.0 3.5 2 1 0 3 3 3 2 TPR repeat TPR_19 PF14559.6 KKK13840.1 - 0.00016 22.1 0.4 0.23 12.0 0.0 3.0 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 KKK13840.1 - 0.00028 21.4 6.6 0.012 16.3 0.1 3.2 2 1 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 KKK13840.1 - 0.0023 18.0 0.2 0.0063 16.6 0.2 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.6 KKK13840.1 - 0.0045 17.1 3.2 2.1 8.8 0.0 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 KKK13840.1 - 0.0081 16.7 1.1 1.9 9.3 0.1 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat MIT PF04212.18 KKK13840.1 - 0.034 14.2 2.6 1.3 9.2 0.4 2.5 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_14 PF13428.6 KKK13840.1 - 0.11 13.4 1.5 2.1 9.4 0.4 3.1 1 1 2 3 3 3 0 Tetratricopeptide repeat Kelch_4 PF13418.6 KKK13840.1 - 0.21 11.6 0.2 0.45 10.6 0.0 1.7 2 0 0 2 2 2 0 Galactose oxidase, central domain RE_Bsp6I PF09504.10 KKK13842.1 - 0.063 12.9 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Bsp6I restriction endonuclease Tenui_NCP PF04876.12 KKK13842.1 - 0.18 11.4 0.2 0.43 10.2 0.1 1.6 2 0 0 2 2 2 0 Tenuivirus major non-capsid protein BTB PF00651.31 KKK13842.1 - 0.18 12.0 0.0 0.39 11.0 0.0 1.6 1 0 0 1 1 1 0 BTB/POZ domain Peptidase_M1 PF01433.20 KKK13843.1 - 5.4e-46 156.9 0.3 7.7e-46 156.4 0.3 1.2 1 0 0 1 1 1 1 Peptidase family M1 domain Leuk-A4-hydro_C PF09127.11 KKK13843.1 - 5.5e-37 126.3 0.0 1.3e-36 125.1 0.0 1.7 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1_N PF17900.1 KKK13843.1 - 2.9e-28 99.3 0.1 4.2e-28 98.8 0.1 1.2 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Peptidase_M61 PF05299.12 KKK13843.1 - 0.14 12.6 1.7 2.2 8.7 1.7 2.6 1 1 0 1 1 1 0 M61 glycyl aminopeptidase Ubiq_cyt_C_chap PF03981.12 KKK13844.1 - 1.8e-38 131.8 0.1 5.4e-38 130.3 0.1 1.7 2 0 0 2 2 2 1 Ubiquinol-cytochrome C chaperone NumbF PF06311.12 KKK13844.1 - 0.073 13.6 1.1 0.15 12.6 1.1 1.5 1 0 0 1 1 1 0 NUMB domain TIP41 PF04176.13 KKK13845.1 - 1.2e-53 181.1 1.6 2.9e-44 150.6 0.0 2.0 1 1 1 2 2 2 2 TIP41-like family MIT PF04212.18 KKK13846.1 - 4.7e-12 45.8 2.2 1.3e-11 44.4 1.0 2.4 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain TbpB_A PF17484.2 KKK13846.1 - 0.095 13.5 0.8 1.8 9.4 0.1 2.6 2 0 0 2 2 2 0 N-Lobe handle Tf-binding protein B Zn_clus PF00172.18 KKK13847.1 - 3.8e-08 33.3 6.8 3.8e-08 33.3 6.8 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CDC45 PF02724.14 KKK13847.1 - 0.087 11.1 3.0 0.13 10.5 3.0 1.2 1 0 0 1 1 1 0 CDC45-like protein RXT2_N PF08595.11 KKK13847.1 - 0.14 12.2 1.6 0.27 11.3 1.6 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal DNA_pol_phi PF04931.13 KKK13847.1 - 0.33 9.0 14.0 0.47 8.5 14.0 1.1 1 0 0 1 1 1 0 DNA polymerase phi SDA1 PF05285.12 KKK13847.1 - 0.77 9.1 4.9 1.2 8.5 4.9 1.1 1 0 0 1 1 1 0 SDA1 Sigma70_ner PF04546.13 KKK13847.1 - 1.5 8.7 11.7 2.4 8.0 11.7 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF4611 PF15387.6 KKK13847.1 - 1.8 8.8 8.9 4.4 7.6 8.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) PBP1_TM PF14812.6 KKK13847.1 - 2.7 8.4 11.1 6.8 7.1 11.1 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Peptidase_M24 PF00557.24 KKK13849.1 - 1.3e-57 194.9 0.0 1.8e-57 194.4 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 KKK13849.1 - 1.7e-24 85.9 0.0 3.6e-24 84.8 0.0 1.5 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain 4HBT PF03061.22 KKK13850.1 - 3e-10 40.3 0.1 4.2e-10 39.8 0.1 1.3 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.6 KKK13850.1 - 0.018 15.2 0.0 0.02 15.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4442) PC4 PF02229.16 KKK13851.1 - 1.5e-23 82.2 0.1 2.6e-23 81.4 0.1 1.4 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) PXA PF02194.15 KKK13852.1 - 2.1e-32 112.6 0.2 5.9e-32 111.1 0.2 1.8 1 0 0 1 1 1 1 PXA domain Nexin_C PF08628.12 KKK13852.1 - 1.5e-22 80.3 0.0 6.5e-22 78.2 0.0 2.2 2 0 0 2 2 2 1 Sorting nexin C terminal PX PF00787.24 KKK13852.1 - 8e-09 35.5 0.0 1.2e-07 31.7 0.0 2.4 2 0 0 2 2 2 1 PX domain DDHD PF02862.17 KKK13853.1 - 2.1e-51 175.3 0.7 2.1e-51 175.3 0.7 3.2 2 2 0 2 2 2 1 DDHD domain WWE PF02825.20 KKK13853.1 - 0.06 13.9 4.6 1.1 9.9 2.0 3.5 2 1 0 2 2 2 0 WWE domain Usp PF00582.26 KKK13853.1 - 0.098 13.2 1.2 0.24 11.9 1.2 1.6 1 0 0 1 1 1 0 Universal stress protein family Lipase_3 PF01764.25 KKK13853.1 - 0.2 11.5 0.0 0.41 10.5 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) CH PF00307.31 KKK13854.1 - 8.6e-76 251.2 0.0 6.4e-21 74.6 0.0 4.1 4 0 0 4 4 4 4 Calponin homology (CH) domain EF-hand_7 PF13499.6 KKK13854.1 - 1.3e-07 32.0 1.6 1.3e-05 25.6 0.6 2.8 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 KKK13854.1 - 0.00021 20.9 3.9 0.029 14.3 0.1 3.2 3 0 0 3 3 3 2 EF-hand domain CAMSAP_CH PF11971.8 KKK13854.1 - 0.00044 20.0 0.0 0.21 11.4 0.0 3.6 4 0 0 4 4 4 1 CAMSAP CH domain EF-hand_1 PF00036.32 KKK13854.1 - 0.00069 19.0 1.4 0.75 9.5 0.1 3.4 3 0 0 3 3 3 2 EF hand EF-hand_5 PF13202.6 KKK13854.1 - 0.012 15.0 2.6 2 8.1 0.2 2.8 2 0 0 2 2 2 0 EF hand RRM_1 PF00076.22 KKK13855.1 - 8.4e-12 44.7 0.0 1.2e-11 44.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KKK13855.1 - 0.00058 19.8 0.0 0.00084 19.3 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Ribosomal_L18 PF17135.4 KKK13856.1 - 1e-92 308.7 3.9 1.4e-92 308.3 3.9 1.2 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Mito_carr PF00153.27 KKK13856.1 - 8.8e-71 233.9 0.7 8.8e-23 80.0 0.0 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KKK13856.1 - 0.0013 17.9 0.3 0.036 13.2 0.0 3.0 2 1 1 3 3 3 1 Gammaproteobacterial serine protease Ribosomal_L27A PF00828.19 KKK13856.1 - 0.0013 19.4 0.0 0.0033 18.1 0.0 1.7 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Aldedh PF00171.22 KKK13857.1 - 8.2e-15 54.3 9.1 1.2e-09 37.3 7.1 2.9 2 1 0 2 2 2 2 Aldehyde dehydrogenase family PCI PF01399.27 KKK13858.1 - 0.011 16.2 0.0 0.076 13.5 0.0 2.4 3 0 0 3 3 3 0 PCI domain TPR_1 PF00515.28 KKK13858.1 - 0.038 13.8 0.2 0.081 12.8 0.2 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.17 KKK13858.1 - 0.041 14.0 0.1 0.11 12.7 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat GPI-anchored PF10342.9 KKK13859.1 - 1.8e-14 54.2 0.0 3.5e-14 53.3 0.0 1.5 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family KRE9 PF05390.11 KKK13859.1 - 3.1e-13 50.3 3.5 6.8e-13 49.3 3.5 1.5 1 0 0 1 1 1 1 Yeast cell wall synthesis protein KRE9/KNH1 AA_kinase PF00696.28 KKK13860.1 - 9.9e-40 136.6 0.7 1.4e-39 136.1 0.7 1.2 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.20 KKK13860.1 - 5.4e-18 64.7 0.2 2.3e-16 59.5 0.0 2.4 2 0 0 2 2 2 1 PUA domain PALP PF00291.25 KKK13861.1 - 7.8e-67 225.7 0.1 9.5e-67 225.5 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.28 KKK13861.1 - 2.9e-13 50.0 0.1 1.3e-07 31.9 0.0 2.8 2 0 0 2 2 2 2 CBS domain DAP_epimerase PF01678.19 KKK13861.1 - 0.076 13.2 0.0 0.45 10.7 0.0 2.1 2 0 0 2 2 2 0 Diaminopimelate epimerase ACP_syn_III_C PF08541.10 KKK13861.1 - 0.68 10.1 3.0 14 5.9 0.0 2.9 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal SRPRB PF09439.10 KKK13862.1 - 7.8e-26 90.6 0.1 4.8e-24 84.8 0.1 2.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.21 KKK13862.1 - 6.1e-08 32.3 0.0 0.004 16.6 0.0 2.6 2 1 0 2 2 2 2 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KKK13862.1 - 1.7e-05 24.9 0.0 3.1e-05 24.0 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KKK13862.1 - 7.6e-05 23.2 0.1 0.00018 21.9 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.27 KKK13862.1 - 0.00012 22.6 0.0 0.0002 21.9 0.0 1.4 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 KKK13862.1 - 0.00098 19.1 0.2 0.0086 16.0 0.2 2.2 2 0 0 2 2 2 1 RsgA GTPase Sigma54_activat PF00158.26 KKK13862.1 - 0.0018 18.0 0.0 1.5 8.5 0.0 2.2 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_29 PF13555.6 KKK13862.1 - 0.0029 17.3 0.1 0.0063 16.2 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain GTP_EFTU PF00009.27 KKK13862.1 - 0.0041 16.7 0.0 0.11 12.1 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 KKK13862.1 - 0.01 16.1 0.1 0.02 15.2 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_21 PF13304.6 KKK13862.1 - 0.015 15.2 0.0 0.024 14.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system PduV-EutP PF10662.9 KKK13862.1 - 0.03 14.1 0.1 0.056 13.2 0.1 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_5 PF07728.14 KKK13862.1 - 0.07 13.1 0.0 0.16 11.9 0.0 1.7 2 0 0 2 2 1 0 AAA domain (dynein-related subfamily) AAA_23 PF13476.6 KKK13862.1 - 0.073 13.6 0.0 0.15 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain Roc PF08477.13 KKK13862.1 - 0.074 13.3 0.0 0.32 11.2 0.0 2.0 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Rad17 PF03215.15 KKK13862.1 - 0.11 12.4 0.1 0.19 11.6 0.1 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_18 PF13238.6 KKK13862.1 - 0.14 12.7 0.0 0.28 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 KKK13862.1 - 0.15 11.4 0.0 0.33 10.3 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 KKK13862.1 - 0.17 11.4 0.1 0.29 10.6 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 KKK13862.1 - 0.17 11.6 0.0 0.32 10.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain Septin PF00735.18 KKK13862.1 - 0.2 10.9 0.0 0.35 10.1 0.0 1.3 1 0 0 1 1 1 0 Septin AAA_28 PF13521.6 KKK13862.1 - 0.2 11.9 0.1 0.32 11.2 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KKK13862.1 - 0.22 11.7 0.4 0.34 11.0 0.3 1.5 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 KKK13862.1 - 0.28 11.6 1.0 1 9.8 1.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Na_Ca_ex PF01699.24 KKK13863.1 - 3.4e-22 79.0 31.1 1.8e-13 50.7 8.4 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein HAUS-augmin3 PF14932.6 KKK13863.1 - 0.0027 17.3 6.6 0.0027 17.3 6.6 3.1 3 1 0 3 3 3 1 HAUS augmin-like complex subunit 3 SlyX PF04102.12 KKK13863.1 - 0.034 14.7 15.9 0.069 13.8 3.2 3.9 3 1 1 4 4 4 0 SlyX DUF898 PF05987.13 KKK13863.1 - 0.062 12.3 1.5 0.069 12.2 0.2 1.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF898) Adenine_glyco PF03352.13 KKK13863.1 - 0.13 12.1 0.1 1.6 8.4 0.0 2.6 2 0 0 2 2 2 0 Methyladenine glycosylase MIG-14_Wnt-bd PF06664.12 KKK13863.1 - 1.7 7.8 8.5 0.1 11.8 1.5 2.1 2 0 0 2 2 2 0 Wnt-binding factor required for Wnt secretion Peptidase_M76 PF09768.9 KKK13864.1 - 9.7e-75 250.1 2.6 1.2e-74 249.8 2.6 1.1 1 0 0 1 1 1 1 Peptidase M76 family HNH_5 PF14279.6 KKK13864.1 - 0.016 15.1 0.8 0.11 12.4 0.1 2.3 2 0 0 2 2 2 0 HNH endonuclease SprT-like PF10263.9 KKK13864.1 - 0.034 14.0 2.3 0.036 13.9 0.9 1.7 1 1 1 2 2 2 0 SprT-like family Peptidase_M13 PF01431.21 KKK13864.1 - 0.086 12.4 0.1 0.13 11.8 0.1 1.3 1 0 0 1 1 1 0 Peptidase family M13 Peptidase_M91 PF14891.6 KKK13864.1 - 0.11 12.8 0.1 0.17 12.2 0.1 1.3 1 0 0 1 1 1 0 Effector protein Pkinase PF00069.25 KKK13865.1 - 1.9e-71 240.5 0.0 2.4e-71 240.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK13865.1 - 1.8e-44 152.0 0.0 2.3e-44 151.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KKK13865.1 - 1.1e-07 31.5 0.0 3.8e-07 29.7 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 KKK13865.1 - 7.7e-05 22.1 0.2 0.00013 21.4 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KKK13865.1 - 0.0042 16.1 0.0 0.0073 15.3 0.0 1.4 1 0 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 KKK13865.1 - 0.062 12.9 0.1 0.21 11.2 0.0 1.7 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 KKK13865.1 - 0.066 13.1 0.1 0.097 12.6 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 KKK13865.1 - 0.093 12.3 0.1 0.26 10.8 0.0 1.7 2 1 1 3 3 3 0 RIO1 family DUF3237 PF11578.8 KKK13878.1 - 8.6e-20 71.1 0.0 9.5e-20 71.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) GSG-1 PF07803.11 KKK13878.1 - 0.029 14.3 0.1 0.065 13.2 0.1 1.6 1 1 0 1 1 1 0 GSG1-like protein Asn_synthase PF00733.21 KKK13879.1 - 3.1e-64 217.9 0.0 4.2e-64 217.4 0.0 1.1 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.6 KKK13879.1 - 1.2e-36 125.3 0.0 2e-36 124.6 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 KKK13879.1 - 2.6e-29 102.1 0.0 4.3e-29 101.4 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 KKK13879.1 - 0.00072 19.1 0.0 0.0014 18.1 0.0 1.4 1 0 0 1 1 1 1 Aluminium induced protein Ctr PF04145.15 KKK13880.1 - 3.1e-32 112.2 0.2 3.8e-32 112.0 0.2 1.1 1 0 0 1 1 1 1 Ctr copper transporter family PAP2 PF01569.21 KKK13880.1 - 5.6 6.7 8.1 21 4.9 8.1 1.9 1 1 0 1 1 1 0 PAP2 superfamily AATase PF07247.12 KKK13882.1 - 2.4e-18 66.0 0.0 4.3e-18 65.2 0.0 1.4 1 1 0 1 1 1 1 Alcohol acetyltransferase Condensation PF00668.20 KKK13882.1 - 0.0052 15.5 0.0 0.032 12.9 0.0 2.2 3 0 0 3 3 3 1 Condensation domain Ferric_reduct PF01794.19 KKK13883.1 - 8.5e-22 77.6 13.0 2e-21 76.4 13.0 1.7 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KKK13883.1 - 7.8e-20 71.0 0.0 1.5e-19 70.0 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 KKK13883.1 - 4.7e-19 69.0 0.0 9.8e-19 68.0 0.0 1.5 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Abhydrolase_2 PF02230.16 KKK13884.1 - 1.7e-61 207.8 0.0 2.1e-61 207.5 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 KKK13884.1 - 3.7e-08 32.9 0.2 1.9e-05 24.0 0.0 2.9 2 1 1 3 3 3 1 Serine aminopeptidase, S33 FSH1 PF03959.13 KKK13884.1 - 1.4e-06 28.1 0.0 4.9e-06 26.3 0.0 1.8 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 KKK13884.1 - 0.00017 22.2 0.0 0.054 14.1 0.0 2.1 1 1 1 2 2 2 2 Alpha/beta hydrolase family DLH PF01738.18 KKK13884.1 - 0.00021 20.9 0.0 0.0003 20.4 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 KKK13884.1 - 0.00026 20.5 0.0 0.016 14.7 0.0 2.3 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 KKK13884.1 - 0.0003 20.7 0.0 0.0007 19.5 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold LIP PF03583.14 KKK13884.1 - 0.017 14.5 0.1 0.27 10.5 0.0 2.1 2 0 0 2 2 2 0 Secretory lipase Abhydrolase_1 PF00561.20 KKK13884.1 - 0.04 13.6 0.9 8.8 5.9 0.9 2.8 1 1 1 2 2 2 0 alpha/beta hydrolase fold Lipase_3 PF01764.25 KKK13884.1 - 0.087 12.7 0.0 0.16 11.8 0.0 1.5 1 1 0 1 1 1 0 Lipase (class 3) Abhydro_lipase PF04083.16 KKK13884.1 - 0.14 11.8 0.0 0.69 9.5 0.0 1.9 2 0 0 2 2 2 0 Partial alpha/beta-hydrolase lipase region FSH1 PF03959.13 KKK13885.1 - 1.5e-35 122.8 0.0 1.8e-35 122.5 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 KKK13885.1 - 0.00014 22.6 0.1 0.00018 22.2 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 KKK13885.1 - 0.063 13.1 0.3 0.15 11.8 0.3 1.6 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase ICL PF00463.21 KKK13886.1 - 5e-186 619.3 0.0 6.2e-186 619.0 0.0 1.0 1 0 0 1 1 1 1 Isocitrate lyase family EutQ PF06249.12 KKK13887.1 - 6.6e-12 45.4 0.0 8.2e-12 45.1 0.0 1.1 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ Cupin_3 PF05899.12 KKK13887.1 - 4.3e-08 32.8 0.0 5.9e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_2 PF07883.11 KKK13887.1 - 1.8e-05 24.4 0.0 2.5e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Cupin domain Pirin PF02678.16 KKK13887.1 - 0.0079 16.2 0.0 0.018 15.0 0.0 1.4 1 1 0 1 1 1 1 Pirin DUF3857 PF12969.7 KKK13887.1 - 0.014 15.4 0.0 0.016 15.3 0.0 1.3 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3857) cNMP_binding PF00027.29 KKK13887.1 - 0.052 13.6 0.0 0.088 12.9 0.0 1.4 1 0 0 1 1 1 0 Cyclic nucleotide-binding domain SH3BGR PF04908.15 KKK13887.1 - 0.071 13.3 0.0 0.15 12.2 0.0 1.6 2 0 0 2 2 2 0 SH3-binding, glutamic acid-rich protein Cupin_6 PF12852.7 KKK13887.1 - 0.16 11.7 0.0 0.18 11.5 0.0 1.1 1 0 0 1 1 1 0 Cupin Fungal_trans_2 PF11951.8 KKK13888.1 - 1.7e-61 208.1 1.9 2.4e-61 207.7 1.9 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF1687 PF07955.11 KKK13889.1 - 1.5e-15 57.8 0.0 2.1e-15 57.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1687) Pkinase PF00069.25 KKK13890.1 - 6.4e-59 199.5 0.0 5.2e-58 196.5 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK13890.1 - 3.1e-27 95.5 0.4 3.3e-19 69.2 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.24 KKK13890.1 - 1.1e-05 26.0 0.6 4.1e-05 24.2 0.6 2.0 1 0 0 1 1 1 1 Protein kinase C terminal domain APH PF01636.23 KKK13890.1 - 0.0013 18.8 0.5 0.16 11.8 0.0 2.8 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kinase-like PF14531.6 KKK13890.1 - 0.0045 16.3 0.1 0.022 14.1 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 KKK13890.1 - 0.017 14.4 0.5 0.09 12.1 0.0 2.1 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KKK13890.1 - 0.018 14.0 0.0 0.045 12.7 0.0 1.7 1 1 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 KKK13893.1 - 1.8e-07 31.3 0.2 2.8e-05 24.2 0.1 2.3 2 0 0 2 2 2 2 Phosphotransferase enzyme family Choline_kinase PF01633.20 KKK13893.1 - 0.043 13.4 0.0 0.091 12.3 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Peptidase_C13 PF01650.18 KKK13894.1 - 9.2e-06 25.4 0.0 1.5e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase C13 family Mito_carr PF00153.27 KKK13896.1 - 1.2e-29 102.0 1.7 1.7e-15 56.7 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Atg8 PF02991.16 KKK13897.1 - 2.3e-47 159.5 0.6 2.9e-47 159.1 0.6 1.1 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 KKK13897.1 - 5.1e-05 23.6 0.1 7.2e-05 23.1 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Coprogen_oxidas PF01218.18 KKK13898.1 - 3.2e-121 403.6 0.0 4e-121 403.3 0.0 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase HOOK PF05622.12 KKK13899.1 - 9.8e-27 93.4 23.6 9.8e-27 93.4 23.6 3.9 2 1 2 4 4 4 1 HOOK protein DUF4407 PF14362.6 KKK13899.1 - 0.0035 16.7 9.8 0.0035 16.7 9.8 5.1 1 1 2 5 5 5 1 Domain of unknown function (DUF4407) CENP-F_leu_zip PF10473.9 KKK13899.1 - 0.046 13.7 70.0 0.37 10.8 11.5 6.6 4 1 2 6 6 6 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4710 PF15828.5 KKK13899.1 - 0.9 9.7 5.3 8.7 6.5 0.1 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4710) Pox_A_type_inc PF04508.12 KKK13899.1 - 2.6 8.0 16.1 17 5.5 0.3 5.9 5 0 0 5 5 5 0 Viral A-type inclusion protein repeat KASH_CCD PF14662.6 KKK13899.1 - 6.4 6.6 77.3 0.023 14.5 16.6 6.8 4 2 3 7 7 7 0 Coiled-coil region of CCDC155 or KASH Fib_alpha PF08702.10 KKK13899.1 - 9.8 6.4 54.0 0.15 12.2 3.6 5.4 5 1 1 6 6 6 0 Fibrinogen alpha/beta chain family Inhibitor_I9 PF05922.16 KKK13900.1 - 0.044 14.5 0.0 0.046 14.4 0.0 1.2 1 0 0 1 1 1 0 Peptidase inhibitor I9 CFIA_Pcf11 PF11526.8 KKK13901.1 - 9.1e-09 35.7 1.3 3.2e-08 33.9 1.3 1.9 1 1 0 1 1 1 1 Subunit of cleavage factor IA Pcf11 CTD_bind PF04818.13 KKK13901.1 - 3.5e-06 27.8 0.0 1.6e-05 25.6 0.0 2.2 2 0 0 2 2 2 1 RNA polymerase II-binding domain. VHS PF00790.19 KKK13901.1 - 0.06 13.2 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 VHS domain zf-RRN7 PF11781.8 KKK13901.1 - 0.36 10.6 2.9 1.9 8.2 0.6 2.3 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 zf-C2HC_2 PF13913.6 KKK13901.1 - 3.5 7.6 6.5 19 5.3 0.2 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type GFO_IDH_MocA PF01408.22 KKK13902.1 - 1.9e-16 61.0 0.1 3.1e-16 60.3 0.1 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KKK13902.1 - 0.0067 16.4 0.0 0.014 15.4 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.16 KKK13902.1 - 0.17 12.5 0.1 0.29 11.8 0.1 1.3 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain MitMem_reg PF13012.6 KKK13903.1 - 1.5e-36 125.3 0.1 2.4e-36 124.6 0.1 1.3 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 KKK13903.1 - 9.6e-32 109.4 0.2 4.8e-31 107.2 0.0 2.0 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease tRNA_bind_2 PF13725.6 KKK13903.1 - 0.11 12.2 8.5 0.16 11.6 8.5 1.2 1 0 0 1 1 1 0 Possible tRNA binding domain Connexin PF00029.19 KKK13903.1 - 0.93 9.2 4.8 1.5 8.5 4.8 1.4 1 0 0 1 1 1 0 Connexin Folliculin PF11704.8 KKK13903.1 - 4.4 7.2 5.8 7.1 6.5 5.8 1.3 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport ADK PF00406.22 KKK13904.1 - 2e-60 203.2 0.1 2.6e-60 202.9 0.1 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 KKK13904.1 - 7.7e-23 81.4 0.8 1.3e-22 80.7 0.2 1.6 1 1 1 2 2 2 1 AAA domain ADK_lid PF05191.14 KKK13904.1 - 3.2e-18 65.4 0.0 7.7e-18 64.2 0.0 1.7 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.6 KKK13904.1 - 1.5e-05 25.5 0.0 2.4e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KKK13904.1 - 0.00051 20.2 0.0 0.00078 19.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain ABC_tran_CTD PF16326.5 KKK13904.1 - 0.044 14.0 0.4 0.17 12.1 0.0 2.1 2 0 0 2 2 2 0 ABC transporter C-terminal domain Methyltransf_11 PF08241.12 KKK13905.1 - 1.3e-15 57.8 0.0 2.8e-15 56.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKK13905.1 - 2.8e-13 50.4 0.0 5.7e-13 49.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KKK13905.1 - 8.8e-08 32.2 0.0 2.3e-07 30.8 0.0 1.7 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KKK13905.1 - 7.6e-06 26.6 0.0 3.2e-05 24.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KKK13905.1 - 1.7e-05 24.7 0.0 2.9e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 KKK13905.1 - 0.038 12.9 0.1 0.25 10.2 0.0 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1698) MetW PF07021.12 KKK13905.1 - 0.12 12.0 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW DnaB_bind PF10410.9 KKK13905.1 - 0.13 12.5 0.0 0.24 11.6 0.0 1.4 1 0 0 1 1 1 0 DnaB-helicase binding domain of primase Dynamin_M PF01031.20 KKK13939.1 - 1.7e-101 339.2 0.0 3.5e-101 338.2 0.0 1.5 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 KKK13939.1 - 7.8e-57 192.0 0.1 1.5e-56 191.0 0.1 1.5 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 KKK13939.1 - 2.8e-30 104.3 4.7 2.8e-30 104.3 4.7 2.2 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 KKK13939.1 - 2.4e-05 24.4 0.4 0.0002 21.4 0.4 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF2226 PF09987.9 KKK13939.1 - 0.0027 17.1 0.7 0.35 10.2 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized protein conserved in archaea (DUF2226) FeoB_N PF02421.18 KKK13939.1 - 0.11 12.1 0.3 18 4.8 0.0 2.7 3 0 0 3 3 3 0 Ferrous iron transport protein B CN_hydrolase PF00795.22 KKK13940.1 - 1e-33 116.8 0.0 1.4e-33 116.3 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Band_7_C PF16200.5 KKK13940.1 - 0.039 14.0 0.0 0.15 12.1 0.0 1.9 2 0 0 2 2 2 0 C-terminal region of band_7 Glyco_trans_2_3 PF13632.6 KKK13941.1 - 9e-36 123.6 6.3 9e-36 123.6 6.3 1.9 1 1 1 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KKK13941.1 - 0.00036 20.5 0.0 0.0021 18.0 0.0 1.9 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KKK13941.1 - 0.018 14.9 0.0 0.059 13.2 0.0 1.9 1 1 0 1 1 1 0 Glycosyl transferase family 2 Tir_receptor_C PF07489.11 KKK13941.1 - 0.091 12.7 0.2 0.16 11.9 0.2 1.3 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus TrkH PF02386.16 KKK13942.1 - 2.1e-146 488.3 2.8 2.1e-146 488.3 2.8 2.1 2 0 0 2 2 2 2 Cation transport protein WD40 PF00400.32 KKK13943.1 - 1.2e-19 70.2 14.0 0.00087 20.1 0.2 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKK13943.1 - 7.6e-10 39.0 1.8 0.19 12.0 0.1 5.4 2 1 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KKK13943.1 - 0.00011 21.4 1.2 0.0058 15.6 0.8 2.9 2 1 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KKK13943.1 - 0.0082 14.8 0.2 0.018 13.7 0.2 1.5 1 0 0 1 1 1 1 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 KKK13943.1 - 0.023 13.3 0.0 0.5 8.8 0.0 2.3 2 0 0 2 2 2 0 Cytochrome D1 heme domain CLTH PF10607.9 KKK13943.1 - 0.14 12.1 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 CTLH/CRA C-terminal to LisH motif domain Frtz PF11768.8 KKK13943.1 - 0.19 10.0 0.1 0.37 9.1 0.1 1.4 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz ATP-synt_ab PF00006.25 KKK13944.1 - 5.6e-109 362.8 0.0 8.2e-109 362.2 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.5 KKK13944.1 - 1e-45 154.5 0.0 1.8e-45 153.7 0.0 1.4 1 0 0 1 1 1 1 ATPsynthase alpha/beta subunit N-term extension ATP-synt_ab_N PF02874.23 KKK13944.1 - 1.8e-15 57.2 1.9 3.7e-15 56.2 1.9 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain LPD23 PF18838.1 KKK13944.1 - 0.0076 16.0 0.1 0.014 15.1 0.1 1.4 1 0 0 1 1 1 1 Large polyvalent protein associated domain 23 NB-ARC PF00931.22 KKK13944.1 - 0.056 12.6 0.1 1.6 7.9 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain NIF PF03031.18 KKK13953.1 - 7.4e-27 94.0 0.0 1.4e-26 93.2 0.0 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase YdfA_immunity PF12127.8 KKK13953.1 - 0.15 11.1 2.2 0.23 10.5 2.2 1.1 1 0 0 1 1 1 0 SigmaW regulon antibacterial RskA PF10099.9 KKK13953.1 - 2 8.7 13.9 0.74 10.1 10.5 2.0 2 0 0 2 2 2 0 Anti-sigma-K factor rskA MFS_1 PF07690.16 KKK13956.1 - 3.7e-21 75.4 41.2 3.7e-21 75.4 41.2 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Methyltransf_2 PF00891.18 KKK13957.1 - 4e-12 45.9 0.0 2.1e-11 43.5 0.0 2.0 1 1 1 2 2 2 1 O-methyltransferase domain Methyltransf_23 PF13489.6 KKK13957.1 - 0.0012 18.7 0.0 0.0022 17.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain TPR_8 PF13181.6 KKK13957.1 - 0.24 11.7 1.5 10 6.6 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Transp_cyt_pur PF02133.15 KKK13959.1 - 1.9e-29 102.7 31.8 1.2e-28 100.1 31.8 2.1 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Cation_efflux PF01545.21 KKK13959.1 - 0.0001 22.1 4.1 0.00041 20.1 4.1 2.0 1 1 0 1 1 1 1 Cation efflux family p450 PF00067.22 KKK13960.1 - 1.7e-62 211.7 0.0 2.2e-62 211.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 KKK13961.1 - 3.4e-13 49.2 23.1 4.1e-09 35.8 13.0 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily ABC_tran PF00005.27 KKK13962.1 - 2.2e-52 177.2 0.0 4.7e-30 104.9 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KKK13962.1 - 4.7e-39 134.7 13.8 6.7e-24 85.0 6.8 2.5 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 KKK13962.1 - 1.4e-08 34.4 0.0 0.0013 18.2 0.1 3.7 3 2 0 3 3 2 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 KKK13962.1 - 4.4e-06 26.7 0.2 0.018 14.9 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 KKK13962.1 - 1.1e-05 25.5 0.0 0.021 14.9 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_23 PF13476.6 KKK13962.1 - 4.4e-05 24.1 0.2 0.033 14.7 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KKK13962.1 - 0.00014 22.1 1.9 0.31 11.3 0.1 3.3 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KKK13962.1 - 0.00015 22.2 0.4 0.84 10.0 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.6 KKK13962.1 - 0.0011 18.6 0.0 1.2 8.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 KKK13962.1 - 0.0028 16.9 0.2 0.72 9.1 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin AAA_29 PF13555.6 KKK13962.1 - 0.004 16.9 0.4 2.7 7.8 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain CbiA PF01656.23 KKK13962.1 - 0.0051 16.9 0.0 1.2 9.2 0.0 3.0 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_30 PF13604.6 KKK13962.1 - 0.0064 16.2 0.0 0.36 10.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 KKK13962.1 - 0.0068 16.2 0.0 0.11 12.2 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein TsaE PF02367.17 KKK13962.1 - 0.0068 16.4 0.1 0.35 10.9 0.0 2.6 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE cobW PF02492.19 KKK13962.1 - 0.0071 15.9 0.5 0.29 10.7 0.1 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 KKK13962.1 - 0.0079 16.1 1.0 1 9.3 0.1 2.5 2 0 0 2 2 2 1 NACHT domain MobB PF03205.14 KKK13962.1 - 0.013 15.4 0.7 3.6 7.5 0.1 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA PF00004.29 KKK13962.1 - 0.02 15.3 0.2 9.8 6.6 0.0 3.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_21 PF13304.6 KKK13962.1 - 0.029 14.2 6.0 33 4.1 0.0 5.1 4 1 0 5 5 5 0 AAA domain, putative AbiEii toxin, Type IV TA system DUF2075 PF09848.9 KKK13962.1 - 0.038 13.2 0.3 0.49 9.6 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) RNA_helicase PF00910.22 KKK13962.1 - 0.038 14.4 0.0 11 6.5 0.0 2.9 3 0 0 3 3 3 0 RNA helicase ATPase PF06745.13 KKK13962.1 - 0.043 13.2 0.0 2.4 7.5 0.0 2.5 2 0 0 2 2 2 0 KaiC AAA_7 PF12775.7 KKK13962.1 - 0.044 13.3 0.0 1.7 8.1 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region FtsK_SpoIIIE PF01580.18 KKK13962.1 - 0.048 13.0 0.2 8.2 5.7 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family NB-ARC PF00931.22 KKK13962.1 - 0.067 12.4 0.2 42 3.2 0.1 3.2 3 0 0 3 3 3 0 NB-ARC domain ATP-synt_ab PF00006.25 KKK13962.1 - 0.069 12.8 0.0 4 7.0 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain DnaB_C PF03796.15 KKK13962.1 - 0.078 12.3 0.0 1.4 8.2 0.0 2.5 3 0 0 3 3 3 0 DnaB-like helicase C terminal domain T2SSE PF00437.20 KKK13962.1 - 0.11 11.5 0.0 5.5 6.0 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein APS_kinase PF01583.20 KKK13962.1 - 0.13 12.2 0.5 0.29 11.0 0.0 1.8 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_33 PF13671.6 KKK13962.1 - 0.14 12.3 0.1 19 5.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 KKK13962.1 - 0.16 12.1 5.6 0.14 12.2 0.2 3.0 3 0 0 3 3 3 0 Helicase HerA, central domain Hemerythrin PF01814.23 KKK13963.1 - 3.1e-08 34.3 0.8 5.7e-08 33.4 0.8 1.3 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain ketoacyl-synt PF00109.26 KKK13964.1 - 1.2e-62 211.8 0.0 2.8e-62 210.6 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.6 KKK13964.1 - 3.5e-62 210.3 0.0 1.1e-61 208.8 0.0 1.7 2 0 0 2 2 2 1 Polyketide synthase dehydratase KR PF08659.10 KKK13964.1 - 2.8e-56 190.3 0.7 2.7e-55 187.0 0.2 2.4 2 0 0 2 2 2 1 KR domain Acyl_transf_1 PF00698.21 KKK13964.1 - 6.4e-52 177.0 0.3 1.1e-51 176.3 0.3 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KKK13964.1 - 3.5e-31 107.6 0.1 1e-30 106.2 0.1 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.12 KKK13964.1 - 3.1e-19 69.5 0.0 1.3e-18 67.5 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.6 KKK13964.1 - 2e-16 61.3 0.1 6.3e-15 56.4 0.0 3.4 3 0 0 3 3 3 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KKK13964.1 - 2.8e-16 59.7 0.2 2.8e-15 56.4 0.0 2.9 3 0 0 3 3 3 1 Zinc-binding dehydrogenase KAsynt_C_assoc PF16197.5 KKK13964.1 - 4.3e-16 59.4 0.0 1e-15 58.2 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_23 PF13489.6 KKK13964.1 - 1.1e-14 54.6 0.0 2.4e-14 53.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKK13964.1 - 9.6e-12 45.5 0.0 5.5e-11 43.0 0.0 2.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KKK13964.1 - 4.7e-10 40.0 0.0 1.7e-09 38.2 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.25 KKK13964.1 - 2.5e-08 33.6 0.3 8.1e-06 25.4 0.0 2.8 2 0 0 2 2 2 1 short chain dehydrogenase Methyltransf_31 PF13847.6 KKK13964.1 - 2.5e-08 33.9 0.0 1.4e-07 31.4 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain PP-binding PF00550.25 KKK13964.1 - 8.8e-08 32.4 0.1 2.4e-07 31.0 0.1 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site ADH_N PF08240.12 KKK13964.1 - 6.6e-06 26.0 0.0 5.7e-05 23.0 0.0 2.4 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Thiolase_N PF00108.23 KKK13964.1 - 8.8e-06 25.3 0.6 1.9e-05 24.2 0.1 1.8 2 0 0 2 2 1 1 Thiolase, N-terminal domain Ubie_methyltran PF01209.18 KKK13964.1 - 2.6e-05 23.7 0.0 6e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.9 KKK13964.1 - 0.0015 18.3 0.0 0.013 15.2 0.0 2.5 3 0 0 3 3 3 1 Lysine methyltransferase adh_short_C2 PF13561.6 KKK13964.1 - 0.0051 16.4 0.0 0.02 14.4 0.0 2.0 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase NodS PF05401.11 KKK13964.1 - 0.0087 15.7 0.0 0.022 14.4 0.0 1.6 1 0 0 1 1 1 1 Nodulation protein S (NodS) SAT PF16073.5 KKK13964.1 - 0.072 12.8 2.2 10 5.8 0.0 2.9 3 0 0 3 3 3 0 Starter unit:ACP transacylase in aflatoxin biosynthesis ACP_syn_III PF08545.10 KKK13964.1 - 0.16 11.9 0.7 2.8 7.8 0.4 2.5 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III DPBB_1 PF03330.18 KKK13965.1 - 6e-08 32.9 0.2 6e-08 32.9 0.2 1.5 2 0 0 2 2 2 1 Lytic transglycolase Glyco_hydro_43 PF04616.14 KKK13966.1 - 1.3e-62 211.8 3.1 1.8e-62 211.3 3.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 KKK13966.1 - 2.2e-32 112.4 0.0 3.4e-32 111.8 0.0 1.3 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain Glyco_hydro_2_N PF02837.18 KKK13966.1 - 0.047 13.6 0.1 0.09 12.7 0.1 1.4 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, sugar binding domain DUF5357 PF17310.2 KKK13966.1 - 0.15 10.6 0.0 0.22 10.0 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5357) Trp_DMAT PF11991.8 KKK13967.1 - 7.3e-86 288.8 0.0 8.2e-84 282.1 0.0 2.1 1 1 0 1 1 1 1 Tryptophan dimethylallyltransferase CRAL_TRIO PF00650.20 KKK13968.1 - 1.6e-37 128.7 0.0 2.6e-37 128.0 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 KKK13968.1 - 2.2e-06 27.9 0.0 3.6e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KKK13968.1 - 0.0033 17.6 0.0 0.0094 16.1 0.0 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain FAD_binding_3 PF01494.19 KKK13969.1 - 8.4e-26 91.0 1.0 2.2e-16 60.0 0.1 2.3 2 1 0 2 2 2 2 FAD binding domain FAD_binding_2 PF00890.24 KKK13969.1 - 0.00019 20.7 0.4 0.00034 19.8 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain PALP PF00291.25 KKK13969.1 - 0.0022 17.5 0.0 0.0037 16.7 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme TrkA_N PF02254.18 KKK13969.1 - 0.0024 18.1 0.1 0.0054 17.0 0.0 1.6 2 0 0 2 2 1 1 TrkA-N domain Pyr_redox_3 PF13738.6 KKK13969.1 - 0.003 16.9 0.0 0.0052 16.1 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KKK13969.1 - 0.0039 17.4 0.0 0.014 15.6 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KKK13969.1 - 0.0046 16.6 0.1 0.0098 15.5 0.0 1.8 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KKK13969.1 - 0.0059 15.9 0.0 0.097 11.9 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KKK13969.1 - 0.013 14.6 2.1 0.022 13.9 0.2 2.2 2 1 0 2 2 2 0 Lycopene cyclase protein Pyr_redox PF00070.27 KKK13969.1 - 0.015 15.9 0.0 0.13 12.9 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KKK13969.1 - 0.016 14.5 0.1 11 5.1 0.0 3.0 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase Thi4 PF01946.17 KKK13969.1 - 0.1 11.8 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Thi4 family IlvN PF07991.12 KKK13969.1 - 0.12 11.9 0.1 0.26 10.8 0.1 1.6 1 1 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain MFS_1 PF07690.16 KKK13970.1 - 1.3e-28 99.9 67.1 1.9e-21 76.4 30.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1279 PF06916.13 KKK13970.1 - 0.019 15.5 1.1 0.019 15.5 1.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1279) Abhydrolase_3 PF07859.13 KKK13971.1 - 2.2e-46 158.4 0.0 2.8e-46 158.1 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KKK13971.1 - 2.1e-10 40.1 0.6 6.4e-10 38.5 0.6 1.6 1 1 0 1 1 1 1 Carboxylesterase family Say1_Mug180 PF10340.9 KKK13971.1 - 0.22 10.3 0.0 0.34 9.7 0.0 1.3 1 0 0 1 1 1 0 Steryl acetyl hydrolase AMP-binding PF00501.28 KKK13972.1 - 1.7e-89 300.3 0.0 2.2e-89 300.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KKK13972.1 - 2e-14 54.3 0.0 4.2e-14 53.3 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Pyridoxal_deC PF00282.19 KKK13973.1 - 2.7e-68 230.4 0.0 2.2e-54 184.6 0.0 2.1 2 0 0 2 2 2 2 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.21 KKK13973.1 - 1.3e-07 31.2 0.0 1.8e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 KKK13973.1 - 5.7e-07 28.8 0.0 9.6e-07 28.1 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V AMP-binding PF00501.28 KKK13974.1 - 1.4e-77 261.1 0.0 2e-77 260.6 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 KKK13974.1 - 2.6e-76 257.2 0.0 1.2e-34 119.8 0.0 3.7 3 1 0 3 3 3 3 Condensation domain PP-binding PF00550.25 KKK13974.1 - 8.4e-22 77.3 0.5 3.9e-11 43.1 0.2 2.9 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KKK13974.1 - 0.023 15.7 0.0 0.06 14.3 0.0 1.7 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain Transferase PF02458.15 KKK13974.1 - 0.15 10.7 0.0 0.53 8.9 0.0 1.8 2 0 0 2 2 2 0 Transferase family Zn_clus PF00172.18 KKK13975.1 - 7.5e-08 32.4 6.2 1.4e-07 31.5 6.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PRIMA1 PF16101.5 KKK13975.1 - 0.018 15.1 3.2 0.76 9.8 1.1 2.4 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 CAP_N PF01213.19 KKK13975.1 - 0.25 10.8 6.5 0.045 13.2 2.7 1.6 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg PF05308.11 KKK13975.1 - 0.3 11.2 4.0 0.15 12.2 1.5 1.7 2 0 0 2 2 2 0 Mitochondrial fission regulator p450 PF00067.22 KKK13976.1 - 8.9e-77 258.8 0.0 9.8e-77 258.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_25 PF13649.6 KKK13977.1 - 6.9e-07 29.9 0.0 2.1e-06 28.3 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KKK13977.1 - 0.0013 19.3 0.0 0.0028 18.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Pox_MCEL PF03291.16 KKK13977.1 - 0.0037 16.4 0.0 0.0056 15.8 0.0 1.2 1 0 0 1 1 1 1 mRNA capping enzyme Methyltransf_31 PF13847.6 KKK13977.1 - 0.005 16.6 0.0 0.0073 16.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Aldedh PF00171.22 KKK13979.1 - 2.7e-09 36.1 0.0 4.3e-05 22.2 0.0 2.3 2 0 0 2 2 2 2 Aldehyde dehydrogenase family MitoNEET_N PF10660.9 KKK13979.1 - 0.27 11.3 1.0 0.66 10.0 1.0 1.6 1 0 0 1 1 1 0 Iron-containing outer mitochondrial membrane protein N-terminus AA_permease PF00324.21 KKK13980.1 - 4.7e-53 180.5 44.2 3.9e-32 111.5 21.6 3.0 2 1 0 2 2 2 2 Amino acid permease AA_permease_2 PF13520.6 KKK13980.1 - 1.7e-20 73.3 42.2 1.7e-20 73.3 42.2 2.9 1 1 0 1 1 1 1 Amino acid permease TauD PF02668.16 KKK13982.1 - 4.1e-13 49.7 0.4 6.1e-12 45.9 0.8 2.4 2 1 0 2 2 2 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 KKK13982.1 - 0.00043 19.5 0.0 0.00075 18.7 0.0 1.4 1 0 0 1 1 1 1 CsiD SLT_beta PF02258.16 KKK13983.1 - 0.12 12.4 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 Shiga-like toxin beta subunit AAT PF03417.16 KKK13984.1 - 1.1e-24 87.5 0.0 1.4e-24 87.1 0.0 1.1 1 0 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase Pkinase PF00069.25 KKK13985.1 - 2.4e-19 69.7 0.0 4.1e-19 69.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK13985.1 - 6.3e-14 51.9 0.0 3.8e-13 49.3 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase CorA PF01544.18 KKK13986.1 - 0.003 16.9 3.7 0.0081 15.5 3.7 1.8 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein ACOX PF01756.19 KKK13988.1 - 4.3e-44 150.2 0.1 1.5e-43 148.4 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 KKK13988.1 - 5.5e-27 94.8 0.2 1.1e-26 93.8 0.2 1.6 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 KKK13988.1 - 8.7e-12 45.1 0.0 2.4e-11 43.7 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 KKK13988.1 - 1.8e-05 25.0 0.6 0.0029 17.8 0.6 2.5 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain DIOX_N PF14226.6 KKK13989.1 - 2.1e-28 99.4 0.1 3.2e-28 98.9 0.1 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KKK13989.1 - 3.1e-21 75.8 0.0 6.7e-21 74.7 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily LigB PF02900.18 KKK13990.1 - 6.3e-14 51.7 0.0 7.7e-14 51.4 0.0 1.1 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase Nsp3_PL2pro PF12124.8 KKK13990.1 - 0.2 11.5 0.0 0.39 10.5 0.0 1.4 1 0 0 1 1 1 0 Coronavirus polyprotein cleavage domain Fungal_trans PF04082.18 KKK13991.1 - 1.5e-14 53.7 0.2 2.6e-14 52.9 0.2 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK13991.1 - 4.9e-06 26.6 12.6 9e-06 25.7 12.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2 PF00096.26 KKK13991.1 - 0.0014 19.0 3.4 0.0037 17.6 1.6 2.7 2 0 0 2 2 2 1 Zinc finger, C2H2 type Methyltransf_23 PF13489.6 KKK13992.1 - 1.7e-20 73.5 0.0 2.3e-20 73.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KKK13992.1 - 1.8e-14 54.1 0.0 4.5e-14 52.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKK13992.1 - 3e-14 53.5 0.0 7.5e-14 52.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KKK13992.1 - 7.2e-11 42.1 0.0 1e-09 38.4 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KKK13992.1 - 2.1e-09 38.0 0.0 1.1e-08 35.7 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KKK13992.1 - 3.4e-07 29.8 0.0 0.0034 16.7 0.0 2.1 2 0 0 2 2 2 2 ubiE/COQ5 methyltransferase family CMAS PF02353.20 KKK13992.1 - 9.1e-05 21.9 0.0 0.00016 21.1 0.0 1.4 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.14 KKK13992.1 - 0.00015 21.3 0.0 0.0037 16.8 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_2 PF00891.18 KKK13992.1 - 0.002 17.5 0.0 0.011 15.1 0.0 1.9 2 0 0 2 2 2 1 O-methyltransferase domain FtsJ PF01728.19 KKK13992.1 - 0.012 15.8 0.0 0.035 14.2 0.0 1.7 1 1 1 2 2 2 0 FtsJ-like methyltransferase Methyltransf_4 PF02390.17 KKK13992.1 - 0.02 14.3 0.0 0.054 13.0 0.0 1.7 2 0 0 2 2 2 0 Putative methyltransferase PrmA PF06325.13 KKK13992.1 - 0.022 14.2 0.0 0.035 13.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.9 KKK13992.1 - 0.12 12.0 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase PepX_C PF08530.10 KKK13993.1 - 5.4e-44 150.8 0.1 9e-44 150.1 0.1 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Peptidase_S15 PF02129.18 KKK13993.1 - 2.9e-39 135.3 0.6 4e-39 134.8 0.6 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.8 KKK13993.1 - 0.0012 18.2 0.0 0.0021 17.4 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Voltage_CLC PF00654.20 KKK13997.1 - 4.9e-88 295.8 22.1 4.9e-88 295.8 22.1 1.9 2 0 0 2 2 2 1 Voltage gated chloride channel Lipase_GDSL_2 PF13472.6 KKK13998.1 - 4.1e-25 89.2 0.0 8.6e-25 88.2 0.0 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KKK13998.1 - 3.9e-17 62.9 0.0 4.8e-17 62.6 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Pectate_lyase PF03211.13 KKK13999.1 - 2.1e-83 278.8 6.3 2.4e-83 278.7 6.3 1.0 1 0 0 1 1 1 1 Pectate lyase Isochorismatase PF00857.20 KKK14000.1 - 1.2e-20 74.4 0.0 1.6e-20 74.0 0.0 1.2 1 0 0 1 1 1 1 Isochorismatase family Glyco_hydro_16 PF00722.21 KKK14009.1 - 3.6e-33 114.5 1.6 5.4e-33 113.9 1.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 RTC PF01137.21 KKK14011.1 - 2.6e-49 167.4 0.0 3.4e-49 167.0 0.0 1.1 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase CDPS PF16715.5 KKK14011.1 - 0.18 11.4 0.0 0.29 10.7 0.0 1.3 1 0 0 1 1 1 0 Cyclodipeptide synthase DUF2439 PF10382.9 KKK14012.1 - 1.4e-28 99.0 0.3 2.2e-28 98.4 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) GREB1 PF15782.5 KKK14012.1 - 1.2 6.1 2.8 1.9 5.5 2.8 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SH3_9 PF14604.6 KKK14013.1 - 7.8e-15 54.5 0.1 1.4e-14 53.7 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KKK14013.1 - 5.4e-13 48.3 0.1 9.9e-13 47.5 0.1 1.5 1 0 0 1 1 1 1 SH3 domain BAR PF03114.18 KKK14013.1 - 3e-12 46.7 1.8 3e-12 46.7 1.8 1.8 1 1 1 2 2 2 1 BAR domain SH3_2 PF07653.17 KKK14013.1 - 9.4e-11 41.2 0.0 2.1e-10 40.1 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain DUF4541 PF15074.6 KKK14013.1 - 0.32 11.6 3.5 0.72 10.5 3.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4541) zf-CCCH PF00642.24 KKK14014.1 - 1.7e-08 34.1 2.2 3.5e-08 33.2 2.2 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_3 PF13920.6 KKK14014.1 - 4.2e-07 29.7 6.6 7.8e-07 28.9 6.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KKK14014.1 - 2.1e-06 27.4 8.9 3.7e-06 26.7 8.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KKK14014.1 - 2.7e-06 27.3 7.0 5.4e-06 26.3 7.0 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KKK14014.1 - 6.3e-06 26.1 8.8 1.1e-05 25.3 8.8 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KKK14014.1 - 8.3e-06 25.6 10.6 1.5e-05 24.8 10.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf_CCCH_4 PF18345.1 KKK14014.1 - 1.5e-05 24.8 5.1 3.5e-05 23.7 5.1 1.7 1 0 0 1 1 1 1 Zinc finger domain zf-RING_10 PF16685.5 KKK14014.1 - 2.1e-05 24.6 3.9 5e-05 23.4 3.9 1.6 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-RING_2 PF13639.6 KKK14014.1 - 0.0004 20.7 7.2 0.0004 20.7 7.2 1.6 2 0 0 2 2 2 1 Ring finger domain zf-CCCH_4 PF18044.1 KKK14014.1 - 0.00086 19.0 2.1 0.00086 19.0 2.1 2.1 2 0 0 2 2 1 1 CCCH-type zinc finger Prok-RING_4 PF14447.6 KKK14014.1 - 0.0017 18.1 6.5 0.0031 17.3 6.5 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 ProSAAS PF07259.12 KKK14014.1 - 0.0082 16.1 0.0 0.024 14.6 0.0 1.8 1 0 0 1 1 1 1 ProSAAS precursor zf-C3HC4_4 PF15227.6 KKK14014.1 - 0.027 14.6 9.0 0.059 13.5 9.0 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-Nse PF11789.8 KKK14014.1 - 0.12 12.2 2.0 0.24 11.2 2.0 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-rbx1 PF12678.7 KKK14014.1 - 0.33 11.3 4.8 0.63 10.4 4.8 1.4 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-CCCH_2 PF14608.6 KKK14014.1 - 3.2 8.4 8.4 0.19 12.3 3.0 1.8 2 0 0 2 2 1 0 RNA-binding, Nab2-type zinc finger Mcp5_PH PF12814.7 KKK14015.1 - 7.6e-46 155.2 0.4 1.5e-45 154.2 0.4 1.5 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology PH PF00169.29 KKK14015.1 - 8.4e-07 29.5 0.1 2.1e-06 28.2 0.1 1.6 1 0 0 1 1 1 1 PH domain Flagellin_C PF00700.21 KKK14015.1 - 0.083 13.3 0.1 0.32 11.4 0.1 2.1 1 0 0 1 1 1 0 Bacterial flagellin C-terminal helical region MukF_C PF17193.4 KKK14015.1 - 1.4 9.1 4.9 0.45 10.7 1.4 1.9 2 1 0 2 2 2 0 MukF C-terminal domain DUF3431 PF11913.8 KKK14016.1 - 1.3e-85 286.5 0.5 1.9e-85 286.0 0.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) Asp PF00026.23 KKK14027.1 - 6.1e-46 157.3 1.6 9.3e-46 156.7 1.6 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.6 KKK14027.1 - 1.9e-05 25.2 0.5 4.5 8.0 0.0 3.7 3 0 0 3 3 3 3 Aspartyl protease TAXi_N PF14543.6 KKK14027.1 - 7.8e-05 23.0 0.7 0.0003 21.1 0.0 2.3 3 0 0 3 3 3 1 Xylanase inhibitor N-terminal MatB PF16449.5 KKK14027.1 - 0.0041 16.9 0.1 0.015 15.1 0.0 1.9 1 1 1 2 2 2 1 Fimbrillin MatB TAXi_C PF14541.6 KKK14027.1 - 0.0043 16.8 0.0 0.069 12.9 0.0 2.3 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.6 KKK14027.1 - 0.067 13.8 0.4 15 6.3 0.0 3.5 3 0 0 3 3 3 0 gag-polyprotein putative aspartyl protease Glyco_hydro_43 PF04616.14 KKK14028.1 - 6.3e-23 81.5 0.2 1.2e-22 80.6 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 YIF1 PF03878.15 KKK14039.1 - 4.1e-101 337.5 3.4 4.8e-101 337.3 3.4 1.0 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.17 KKK14039.1 - 8.9e-06 25.5 6.2 8.9e-06 25.5 6.2 1.8 2 0 0 2 2 2 1 Yip1 domain SRP-alpha_N PF04086.13 KKK14040.1 - 1.3e-78 264.9 0.0 1.7e-78 264.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54 PF00448.22 KKK14040.1 - 3.4e-50 170.4 0.0 5.5e-50 169.7 0.0 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.19 KKK14040.1 - 1.2e-10 41.4 0.1 3.5e-10 39.9 0.1 1.8 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain MeaB PF03308.16 KKK14040.1 - 9.2e-06 24.8 0.0 1.7e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 KKK14040.1 - 7.1e-05 22.6 0.0 0.00014 21.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KKK14040.1 - 0.0033 17.8 0.0 0.0072 16.7 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_31 PF13614.6 KKK14040.1 - 0.038 13.9 0.1 0.24 11.3 0.0 2.1 1 1 1 2 2 2 0 AAA domain CbiA PF01656.23 KKK14040.1 - 0.046 13.8 0.0 0.17 12.0 0.0 2.0 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Fer4_NifH PF00142.18 KKK14040.1 - 0.054 12.9 0.0 0.096 12.1 0.0 1.4 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_24 PF13479.6 KKK14040.1 - 0.13 12.0 0.0 0.42 10.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KKK14040.1 - 0.14 12.6 0.0 0.68 10.4 0.0 2.1 2 0 0 2 2 2 0 ABC transporter MMR_HSR1 PF01926.23 KKK14040.1 - 0.58 10.3 2.1 1.4 9.0 0.4 2.5 2 1 0 2 2 2 0 50S ribosome-binding GTPase MFS_1 PF07690.16 KKK14041.1 - 2.2e-40 138.7 44.6 1e-34 120.0 16.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KKK14041.1 - 2.6e-10 39.8 12.0 1.3e-09 37.5 0.2 2.4 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.7 KKK14041.1 - 3.1e-06 26.3 5.7 8.1e-06 24.9 0.1 3.0 2 1 0 2 2 2 1 MFS_1 like family MFS_4 PF06779.14 KKK14041.1 - 0.00024 20.5 0.9 0.00024 20.5 0.9 2.5 3 0 0 3 3 3 1 Uncharacterised MFS-type transporter YbfB MFS_2 PF13347.6 KKK14041.1 - 0.0015 17.2 14.1 0.004 15.8 1.7 3.3 2 1 1 3 3 3 2 MFS/sugar transport protein TRI12 PF06609.13 KKK14041.1 - 0.0036 15.8 1.0 0.0058 15.1 1.0 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF2530 PF10745.9 KKK14041.1 - 0.065 13.5 2.0 1.7 9.0 1.1 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) TPR_12 PF13424.6 KKK14042.1 - 1.2e-22 79.9 7.4 3.6e-10 40.0 3.7 4.8 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_10 PF13374.6 KKK14042.1 - 2.3e-18 65.4 5.8 2.9e-06 27.0 0.4 6.1 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_7 PF13176.6 KKK14042.1 - 3.6e-06 26.6 8.2 0.081 13.0 0.1 5.0 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 KKK14042.1 - 0.00099 19.1 11.0 0.45 10.9 0.6 6.2 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_2 PF07719.17 KKK14042.1 - 0.0016 18.4 15.0 3.5 8.0 1.1 7.0 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_16 PF13432.6 KKK14042.1 - 0.0077 16.9 16.0 0.008 16.8 0.1 4.8 4 2 1 5 5 4 1 Tetratricopeptide repeat zf-C2H2 PF00096.26 KKK14042.1 - 0.012 16.1 0.1 0.012 16.1 0.1 4.1 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KKK14042.1 - 0.015 16.1 0.1 0.015 16.1 0.1 4.4 5 0 0 5 5 3 0 C2H2-type zinc finger zf-met PF12874.7 KKK14042.1 - 0.042 14.2 2.8 0.14 12.6 0.1 3.0 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KKK14042.1 - 0.043 14.1 0.1 0.043 14.1 0.1 3.4 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding RXT2_N PF08595.11 KKK14042.1 - 0.053 13.6 0.2 0.053 13.6 0.2 2.7 2 0 0 2 2 2 0 RXT2-like, N-terminal zf_UBZ PF18439.1 KKK14042.1 - 0.36 10.4 2.0 7.2 6.3 0.1 2.9 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger TPR_1 PF00515.28 KKK14042.1 - 0.7 9.8 3.4 24 5.0 0.5 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 KKK14042.1 - 1.1 10.3 13.7 28 5.9 0.2 6.1 4 2 2 6 6 6 0 Tetratricopeptide repeat Inp1 PF12634.7 KKK14042.1 - 2 8.4 7.0 25 4.9 3.4 2.6 2 0 0 2 2 2 0 Inheritance of peroxisomes protein 1 zinc_ribbon_9 PF14369.6 KKK14042.1 - 4.2 7.7 8.8 5.3 7.4 2.5 3.5 3 0 0 3 3 3 0 zinc-ribbon HypA PF01155.19 KKK14042.1 - 8.2 6.5 9.2 0.91 9.6 0.9 3.0 2 1 1 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Mt_ATP-synt_D PF05873.12 KKK14044.1 - 9e-23 80.8 2.7 1.1e-22 80.6 2.7 1.0 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) Herpes_TK_C PF08465.10 KKK14044.1 - 0.058 13.1 0.2 0.15 11.8 0.1 1.7 1 1 0 1 1 1 0 Thymidine kinase from Herpesvirus C-terminal HR1 PF02185.16 KKK14044.1 - 0.16 12.1 4.8 6.6 6.9 0.9 2.3 2 0 0 2 2 2 0 Hr1 repeat DUF2408 PF10303.9 KKK14044.1 - 0.17 12.4 1.7 0.29 11.7 1.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) Enkurin PF13864.6 KKK14044.1 - 0.23 11.9 3.9 2.2 8.8 3.9 2.2 1 1 0 1 1 1 0 Calmodulin-binding Ribosomal_L14e PF01929.17 KKK14045.1 - 1.8e-29 102.0 0.2 2.8e-29 101.4 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.29 KKK14045.1 - 7.6e-08 32.0 1.3 1.4e-07 31.2 1.3 1.5 1 0 0 1 1 1 1 KOW motif Prot_ATP_ID_OB PF16450.5 KKK14045.1 - 0.066 13.2 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Proteasomal ATPase OB C-terminal domain NAC PF01849.18 KKK14046.1 - 2.7e-23 81.7 0.0 3e-22 78.3 0.0 2.2 2 0 0 2 2 2 1 NAC domain Cytomega_UL84 PF06284.11 KKK14046.1 - 0.33 9.4 1.3 0.38 9.2 1.3 1.1 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein SelP_N PF04592.14 KKK14046.1 - 0.63 9.4 5.0 1 8.7 5.0 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region COPI_C PF06957.11 KKK14046.1 - 2.4 6.8 8.0 3.4 6.3 8.0 1.1 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus Myc_N PF01056.18 KKK14046.1 - 3.6 7.4 8.0 1.9 8.3 5.7 1.5 1 1 1 2 2 2 0 Myc amino-terminal region Thiolase_N PF00108.23 KKK14059.1 - 1.4e-74 250.8 0.2 1.9e-74 250.3 0.2 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KKK14059.1 - 5.7e-44 148.7 1.7 1.2e-43 147.6 1.0 1.9 2 0 0 2 2 2 1 Thiolase, C-terminal domain Polysacc_deac_2 PF04748.13 KKK14059.1 - 0.025 13.8 0.1 0.098 11.8 0.0 1.9 2 0 0 2 2 2 0 Divergent polysaccharide deacetylase Ribosomal_L50 PF10501.9 KKK14060.1 - 7.1e-25 87.3 0.2 1.3e-24 86.5 0.2 1.4 1 0 0 1 1 1 1 Ribosomal subunit 39S Rtf2 PF04641.12 KKK14061.1 - 1.4e-70 237.7 3.1 2.4e-70 236.9 3.1 1.3 1 0 0 1 1 1 1 Rtf2 RING-finger zf-Nse PF11789.8 KKK14061.1 - 2.7e-07 30.3 0.5 0.0043 16.8 0.2 2.3 2 0 0 2 2 2 2 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 KKK14061.1 - 0.00065 19.7 0.1 0.0025 17.8 0.0 2.0 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 KKK14061.1 - 0.0018 18.2 0.1 0.0018 18.2 0.1 1.8 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KKK14061.1 - 0.011 15.6 0.1 0.025 14.5 0.1 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-NOSIP PF15906.5 KKK14061.1 - 0.025 14.7 0.0 0.066 13.3 0.0 1.7 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein zf-RING_2 PF13639.6 KKK14061.1 - 0.049 14.0 0.1 0.13 12.6 0.1 1.8 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_2 PF13923.6 KKK14061.1 - 0.12 12.3 0.3 0.12 12.3 0.3 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) PRKCSH-like PF12999.7 KKK14062.1 - 4.6e-46 156.8 13.2 8.5e-28 97.3 1.4 3.2 3 0 0 3 3 3 2 Glucosidase II beta subunit-like Fib_alpha PF08702.10 KKK14062.1 - 0.011 15.9 1.6 1 9.6 0.0 2.3 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Spc29 PF17082.5 KKK14062.1 - 0.15 11.9 1.4 0.24 11.2 0.3 1.6 1 1 1 2 2 2 0 Spindle Pole Component 29 Ldl_recept_a PF00057.18 KKK14062.1 - 0.83 9.9 10.3 0.15 12.3 1.0 2.6 2 0 0 2 2 2 0 Low-density lipoprotein receptor domain class A DivIC PF04977.15 KKK14062.1 - 2.1 8.2 12.3 4.1 7.2 0.8 2.4 2 1 0 2 2 2 0 Septum formation initiator FlaC_arch PF05377.11 KKK14062.1 - 2.5 8.5 7.1 5.1 7.6 0.2 2.5 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) GrpE PF01025.19 KKK14062.1 - 3.4 7.3 13.0 19 4.9 0.5 2.2 1 1 1 2 2 2 0 GrpE DAHP_synth_1 PF00793.20 KKK14063.1 - 4.5e-101 337.3 0.0 5.6e-101 337.0 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family adh_short PF00106.25 KKK14064.1 - 4.2e-13 49.2 0.0 3.2e-08 33.3 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KKK14064.1 - 4.5e-08 32.9 0.0 5.7e-06 26.1 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KKK14064.1 - 0.00022 21.2 0.0 0.00033 20.6 0.0 1.3 1 0 0 1 1 1 1 KR domain Pdase_M17_N2 PF18295.1 KKK14064.1 - 0.081 13.2 0.2 0.19 12.0 0.1 1.6 2 0 0 2 2 2 0 M17 aminopeptidase N-terminal domain 2 DUF2458 PF10454.9 KKK14065.1 - 2.9e-62 209.3 0.0 4.5e-62 208.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2458) Glyco_transf_18 PF15024.6 KKK14065.1 - 0.026 13.1 0.4 0.034 12.8 0.4 1.1 1 0 0 1 1 1 0 Glycosyltransferase family 18 CDC27 PF09507.10 KKK14065.1 - 0.42 10.0 7.8 0.58 9.5 7.8 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF737 PF05300.11 KKK14065.1 - 7.9 6.8 11.2 14 5.9 11.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF737) COX14 PF14880.6 KKK14066.1 - 5.6e-20 70.9 0.5 5.6e-20 70.9 0.5 1.7 2 0 0 2 2 2 1 Cytochrome oxidase c assembly DUF2656 PF10847.8 KKK14066.1 - 0.018 15.2 0.3 0.043 13.9 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2656) Gluconate_2-dh3 PF13618.6 KKK14066.1 - 0.086 13.1 2.1 0.56 10.5 0.9 2.6 1 1 1 2 2 2 0 Gluconate 2-dehydrogenase subunit 3 FOXO_KIX_bdg PF16675.5 KKK14066.1 - 0.11 12.9 0.9 2.5 8.5 0.0 2.5 2 0 0 2 2 2 0 KIX-binding domain of forkhead box O, CR2 Dehydrin PF00257.19 KKK14066.1 - 7.6 7.1 10.0 16 6.0 0.0 2.8 2 1 0 2 2 2 0 Dehydrin Fungal_trans_2 PF11951.8 KKK14074.1 - 2.7e-14 52.8 1.1 4.4e-14 52.1 1.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain WW PF00397.26 KKK14075.1 - 7.4e-12 45.1 0.6 1.6e-11 44.0 0.6 1.6 1 0 0 1 1 1 1 WW domain Exonuc_VII_L PF02601.15 KKK14075.1 - 0.23 11.0 14.2 0.33 10.5 14.2 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit UNC45-central PF11701.8 KKK14105.1 - 4.4e-30 104.7 2.1 2.6e-25 89.1 0.7 3.5 2 1 1 3 3 3 2 Myosin-binding striated muscle assembly central Arm PF00514.23 KKK14105.1 - 1.2e-05 25.2 16.0 4.9 7.3 0.1 8.2 8 0 0 8 8 8 2 Armadillo/beta-catenin-like repeat TPR_15 PF13429.6 KKK14105.1 - 0.0023 17.2 0.6 0.0049 16.1 0.1 1.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 KKK14105.1 - 0.035 13.8 0.0 0.074 12.8 0.0 1.5 1 0 0 1 1 1 0 TPR repeat HEAT_EZ PF13513.6 KKK14105.1 - 0.046 14.2 12.2 32 5.2 0.4 5.9 5 0 0 5 5 5 0 HEAT-like repeat TPR_16 PF13432.6 KKK14105.1 - 0.25 12.0 2.4 0.25 12.0 0.2 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat HEAT_2 PF13646.6 KKK14105.1 - 0.89 10.0 15.6 0.55 10.7 5.7 5.0 5 1 0 5 5 5 0 HEAT repeats HEAT PF02985.22 KKK14105.1 - 2.6 8.6 4.3 47 4.6 0.2 4.5 5 0 0 5 5 5 0 HEAT repeat TPR_14 PF13428.6 KKK14105.1 - 3.9 8.6 7.6 0.22 12.4 0.3 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat PRMT5 PF05185.16 KKK14106.1 - 5.7e-66 221.6 0.0 8.8e-66 221.0 0.0 1.3 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PRMT5_TIM PF17285.2 KKK14106.1 - 6.4e-60 202.5 0.0 6e-58 196.1 0.0 2.2 1 1 0 1 1 1 1 PRMT5 TIM barrel domain PRMT5_C PF17286.2 KKK14106.1 - 1e-48 165.5 0.0 2.2e-48 164.5 0.0 1.6 1 0 0 1 1 1 1 PRMT5 oligomerisation domain Tfb4 PF03850.14 KKK14107.1 - 7e-117 389.8 0.0 8.2e-117 389.6 0.0 1.0 1 0 0 1 1 1 1 Transcription factor Tfb4 PRIMA1 PF16101.5 KKK14107.1 - 0.006 16.6 0.9 0.015 15.3 0.9 1.6 1 0 0 1 1 1 1 Proline-rich membrane anchor 1 CAP_N PF01213.19 KKK14107.1 - 0.096 12.2 1.1 0.14 11.6 1.1 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal GDPD PF03009.17 KKK14108.1 - 2e-68 230.9 0.0 1.4e-67 228.2 0.0 2.3 3 0 0 3 3 3 1 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.7 KKK14108.1 - 4.7e-24 84.8 0.0 6.6e-09 36.2 0.1 3.8 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KKK14108.1 - 1.2e-22 80.0 1.4 2.9e-08 34.1 0.0 5.2 5 0 0 5 5 5 3 Ankyrin repeats (many copies) SPX PF03105.19 KKK14108.1 - 6.3e-22 79.0 13.7 3.3e-10 40.4 0.0 4.1 4 1 1 5 5 5 3 SPX domain Ank_5 PF13857.6 KKK14108.1 - 3.4e-18 65.4 1.0 8.1e-08 32.4 0.1 4.2 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KKK14108.1 - 2.5e-15 55.0 0.3 0.0068 16.8 0.0 6.4 5 0 0 5 5 5 3 Ankyrin repeat Ank PF00023.30 KKK14108.1 - 6e-15 54.9 0.8 0.0027 18.1 0.0 6.6 7 0 0 7 7 7 4 Ankyrin repeat OB_NTP_bind PF07717.16 KKK14109.1 - 2.4e-23 82.3 0.1 9.5e-23 80.4 0.1 2.0 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 KKK14109.1 - 3.1e-20 72.5 0.0 9.5e-20 70.9 0.0 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KKK14109.1 - 1.2e-10 41.7 0.0 5.1e-10 39.7 0.0 2.1 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.29 KKK14109.1 - 7.9e-07 29.0 0.2 1.4e-06 28.2 0.2 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KKK14109.1 - 6.9e-06 26.4 0.0 2.5e-05 24.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 KKK14109.1 - 0.00028 20.6 0.4 0.00098 18.8 0.4 1.9 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_19 PF13245.6 KKK14109.1 - 0.0029 18.0 0.2 0.006 16.9 0.2 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KKK14109.1 - 0.0036 17.0 0.0 0.0069 16.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain Flavi_DEAD PF07652.14 KKK14109.1 - 0.0048 16.9 1.6 0.0052 16.8 0.3 1.7 2 0 0 2 2 2 1 Flavivirus DEAD domain T2SSE PF00437.20 KKK14109.1 - 0.02 13.9 0.0 0.04 13.0 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_7 PF12775.7 KKK14109.1 - 0.039 13.5 0.0 0.097 12.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region ResIII PF04851.15 KKK14109.1 - 0.072 13.1 0.0 14 5.7 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit IstB_IS21 PF01695.17 KKK14109.1 - 0.12 12.0 0.1 2.4 7.9 0.1 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein DUF2075 PF09848.9 KKK14109.1 - 0.15 11.3 0.0 0.23 10.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Spt20 PF12090.8 KKK14110.1 - 0.0042 16.7 18.0 0.0045 16.6 18.0 1.2 1 0 0 1 1 1 1 Spt20 family BET PF17035.5 KKK14110.1 - 0.016 15.4 0.1 0.027 14.6 0.1 1.4 1 0 0 1 1 1 0 Bromodomain extra-terminal - transcription regulation FAM60A PF15396.6 KKK14110.1 - 0.031 14.3 1.3 0.032 14.3 1.3 1.1 1 0 0 1 1 1 0 Protein Family FAM60A PXA PF02194.15 KKK14110.1 - 0.053 13.5 0.6 0.054 13.5 0.6 1.2 1 0 0 1 1 1 0 PXA domain Smr PF01713.21 KKK14110.1 - 0.06 13.7 0.3 0.48 10.8 0.0 2.3 2 1 0 2 2 2 0 Smr domain DUF3464 PF11947.8 KKK14110.1 - 0.066 13.0 2.1 0.09 12.5 2.1 1.2 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 OmpH PF03938.14 KKK14110.1 - 0.083 13.2 11.4 0.13 12.6 10.6 1.7 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Pex14_N PF04695.13 KKK14110.1 - 0.16 12.6 9.5 0.18 12.5 9.5 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SAGA-Tad1 PF12767.7 KKK14110.1 - 0.23 11.2 7.7 5.9 6.6 0.0 2.0 1 1 1 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit TFIIA PF03153.13 KKK14110.1 - 0.56 10.1 18.7 0.57 10.1 18.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FlaG PF03646.15 KKK14110.1 - 0.72 10.1 11.0 14 5.9 10.9 2.1 2 0 0 2 2 2 0 FlaG protein Presenilin PF01080.17 KKK14110.1 - 1.4 7.6 5.0 1.4 7.6 5.0 1.0 1 0 0 1 1 1 0 Presenilin DUF4175 PF13779.6 KKK14110.1 - 3.8 5.3 17.8 4 5.2 17.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) SapB_1 PF05184.15 KKK14110.1 - 6 7.0 7.4 2.9 8.0 1.0 2.8 3 0 0 3 3 3 0 Saposin-like type B, region 1 YscJ_FliF_C PF08345.11 KKK14110.1 - 6 7.2 14.4 6.8 7.0 14.4 1.3 1 1 0 1 1 1 0 Flagellar M-ring protein C-terminal DUF2722 PF10846.8 KKK14110.1 - 8.5 5.2 18.2 10 4.9 18.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) CDC14 PF08045.11 KKK14111.1 - 7.1e-129 428.9 0.0 8e-129 428.8 0.0 1.0 1 0 0 1 1 1 1 Cell division control protein 14, SIN component polyprenyl_synt PF00348.17 KKK14112.1 - 6.7e-64 215.4 0.0 8.5e-64 215.1 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase GST_N_4 PF17172.4 KKK14113.1 - 3.1e-18 66.3 0.1 1.2e-17 64.4 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 KKK14113.1 - 3.8e-17 61.8 0.1 9.2e-17 60.6 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 KKK14113.1 - 3.4e-11 43.5 1.8 3.4e-10 40.3 0.5 2.6 1 1 1 2 2 2 1 Outer mitochondrial membrane transport complex protein GST_C_2 PF13410.6 KKK14113.1 - 0.00051 20.0 0.1 0.00095 19.1 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Sugar_tr PF00083.24 KKK14114.1 - 3.5e-109 365.7 27.3 4e-109 365.5 27.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKK14114.1 - 2.2e-22 79.5 34.7 4.6e-16 58.7 12.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KKK14114.1 - 7.6e-05 21.4 23.6 0.0004 19.1 2.0 3.8 2 2 0 3 3 3 2 MFS/sugar transport protein YccV-like PF08755.11 KKK14115.1 - 3.5e-27 94.8 0.0 7.5e-27 93.7 0.0 1.6 1 0 0 1 1 1 1 Hemimethylated DNA-binding protein YccV like Transglut_core2 PF13369.6 KKK14115.1 - 6.9e-11 42.0 0.0 1.2e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 Transglutaminase-like superfamily DnaJ PF00226.31 KKK14116.1 - 1.6e-24 85.8 2.0 4.1e-24 84.5 2.0 1.7 1 0 0 1 1 1 1 DnaJ domain zf-C2H2_jaz PF12171.8 KKK14116.1 - 4.6e-11 42.7 14.7 1.4e-10 41.1 5.9 3.0 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KKK14116.1 - 2.5e-10 40.4 9.8 6.9e-08 32.6 2.7 2.6 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 KKK14116.1 - 1.6e-07 31.6 7.3 0.0048 17.6 0.5 3.2 3 0 0 3 3 2 2 C2H2-type zinc finger zf-C2H2_2 PF12756.7 KKK14116.1 - 8.5e-06 26.0 9.2 0.00082 19.7 1.6 2.8 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.26 KKK14116.1 - 2.1e-05 24.7 8.0 0.034 14.6 1.3 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 KKK14116.1 - 0.024 14.6 8.5 0.15 12.1 2.3 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 KKK14116.1 - 0.032 14.9 0.1 0.032 14.9 0.1 3.1 3 1 1 4 4 4 0 Zinc finger C2H2-type, 3 repeats zf-H2C2_2 PF13465.6 KKK14116.1 - 0.068 13.6 8.2 0.32 11.5 0.2 3.3 3 0 0 3 3 3 0 Zinc-finger double domain zf-LYAR PF08790.11 KKK14116.1 - 0.48 10.4 5.4 0.24 11.4 0.7 2.5 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger LIM PF00412.22 KKK14116.1 - 0.59 10.4 5.3 1.7 9.0 1.5 2.4 2 0 0 2 2 2 0 LIM domain R3H PF01424.22 KKK14117.1 - 3.4e-12 46.2 0.0 8.6e-12 44.9 0.0 1.7 1 0 0 1 1 1 1 R3H domain G-patch PF01585.23 KKK14117.1 - 1.3e-09 37.8 0.3 3.5e-09 36.4 0.3 1.8 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 KKK14117.1 - 4e-05 23.6 0.1 0.00011 22.2 0.1 1.8 1 0 0 1 1 1 1 G-patch domain VCX_VCY PF15231.6 KKK14117.1 - 0.0051 17.5 2.1 0.013 16.2 2.1 1.7 1 0 0 1 1 1 1 Variable charge X/Y family Phosphoesterase PF04185.14 KKK14119.1 - 6.5e-59 199.9 6.0 1.1e-58 199.1 6.0 1.4 1 1 0 1 1 1 1 Phosphoesterase family VIT1 PF01988.19 KKK14120.1 - 2.6e-46 158.2 7.3 4.1e-45 154.3 7.3 2.0 1 1 0 1 1 1 1 VIT family Peptidase_M19 PF01244.21 KKK14121.1 - 4.9e-102 341.4 0.0 5.7e-102 341.2 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) Amidohydro_2 PF04909.14 KKK14121.1 - 0.074 12.8 0.0 0.21 11.3 0.0 1.8 2 0 0 2 2 2 0 Amidohydrolase AIM5 PF17050.5 KKK14121.1 - 0.087 13.6 0.0 0.25 12.2 0.0 1.8 1 0 0 1 1 1 0 Altered inheritance of mitochondria 5 MFS_1 PF07690.16 KKK14122.1 - 2.3e-46 158.4 49.8 1.4e-43 149.2 48.3 2.9 2 1 0 2 2 2 2 Major Facilitator Superfamily Zn_clus PF00172.18 KKK14123.1 - 3.1e-08 33.6 7.3 3.1e-08 33.6 7.3 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GGACT PF06094.12 KKK14124.1 - 0.12 13.0 0.0 0.14 12.8 0.0 1.2 1 0 0 1 1 1 0 Gamma-glutamyl cyclotransferase, AIG2-like FF PF01846.19 KKK14126.1 - 2.3e-59 197.4 17.0 7.3e-16 58.1 0.5 7.2 6 1 0 6 6 6 6 FF domain WW PF00397.26 KKK14126.1 - 7.6e-17 61.1 13.1 6.4e-08 32.5 0.4 2.7 2 0 0 2 2 2 2 WW domain RhoGAP-FF1 PF16512.5 KKK14126.1 - 0.0017 19.0 11.4 2.5 8.8 0.3 4.7 3 1 1 4 4 4 2 p190-A and -B Rho GAPs FF domain HycH PF07450.11 KKK14126.1 - 0.13 12.7 0.7 0.34 11.3 0.7 1.8 1 0 0 1 1 1 0 Formate hydrogenlyase maturation protein HycH EMP24_GP25L PF01105.24 KKK14126.1 - 0.21 11.5 1.3 0.55 10.1 1.3 1.7 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Glyco_hyd_101C PF17451.2 KKK14126.1 - 0.37 11.1 7.0 5.9 7.2 2.4 2.7 1 1 1 2 2 2 0 Glycosyl hydrolase 101 beta sandwich domain DUF3808 PF10300.9 KKK14127.1 - 6.6e-162 539.5 0.2 6.6e-162 539.5 0.2 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3808) PGK PF00162.19 KKK14128.1 - 2.5e-138 461.1 4.8 9.7e-138 459.2 4.8 1.7 1 1 0 1 1 1 1 Phosphoglycerate kinase SBP_bac_8 PF13416.6 KKK14128.1 - 0.0032 17.3 1.3 0.0058 16.5 0.6 1.7 2 0 0 2 2 2 1 Bacterial extracellular solute-binding protein Trs65 PF12735.7 KKK14129.1 - 1.8e-98 329.9 0.0 2.3e-98 329.5 0.0 1.2 1 0 0 1 1 1 1 TRAPP trafficking subunit Trs65 Mpv17_PMP22 PF04117.12 KKK14129.1 - 6.7e-19 67.9 0.1 1.6e-18 66.7 0.1 1.7 1 0 0 1 1 1 1 Mpv17 / PMP22 family Peptidase_M22 PF00814.25 KKK14173.1 - 1.5e-84 284.0 0.0 1.7e-84 283.7 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family Carbam_trans_N PF02543.15 KKK14173.1 - 0.051 13.2 0.0 0.94 9.1 0.0 2.1 2 0 0 2 2 2 0 Carbamoyltransferase N-terminus BRE1 PF08647.11 KKK14174.1 - 1.5e-28 98.7 12.7 1.5e-28 98.7 12.7 7.2 5 3 2 7 7 6 1 BRE1 E3 ubiquitin ligase zf-C3HC4_3 PF13920.6 KKK14174.1 - 1.5e-09 37.6 7.9 2.7e-09 36.7 7.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KKK14174.1 - 4.5e-09 36.0 8.3 8e-09 35.2 8.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KKK14174.1 - 4.2e-08 32.9 6.6 7.2e-08 32.2 6.6 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 KKK14174.1 - 7e-08 32.2 10.2 1.3e-07 31.4 10.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KKK14174.1 - 1.1e-07 31.8 5.9 2.5e-07 30.6 5.9 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 KKK14174.1 - 2.7e-07 30.8 8.6 4.6e-07 30.1 8.6 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 KKK14174.1 - 7.8e-06 25.8 10.5 1.4e-05 24.9 10.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 KKK14174.1 - 0.0017 18.6 5.7 0.0086 16.3 5.5 2.2 2 0 0 2 2 2 1 RING-H2 zinc finger domain HAP1_N PF04849.13 KKK14174.1 - 0.0019 17.5 23.7 0.0019 17.5 23.7 5.3 2 2 3 5 5 5 1 HAP1 N-terminal conserved region KxDL PF10241.9 KKK14174.1 - 0.0024 18.1 3.9 0.0024 18.1 3.9 6.1 4 2 3 7 7 7 1 Uncharacterized conserved protein Meth_synt_1 PF08267.12 KKK14174.1 - 0.0049 16.4 0.4 0.0049 16.4 0.4 3.0 3 1 0 4 4 4 1 Cobalamin-independent synthase, N-terminal domain Lebercilin PF15619.6 KKK14174.1 - 0.0055 16.4 6.5 0.0055 16.4 6.5 5.3 4 2 1 5 5 4 2 Ciliary protein causing Leber congenital amaurosis disease zf-C3HC4_4 PF15227.6 KKK14174.1 - 0.0064 16.6 6.4 0.012 15.7 6.4 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING DUF1272 PF06906.11 KKK14174.1 - 0.0096 16.0 6.0 0.02 15.0 6.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1272) zf-RING_4 PF14570.6 KKK14174.1 - 0.023 14.5 7.3 0.19 11.6 8.0 2.1 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain CP12 PF02672.15 KKK14174.1 - 0.32 11.8 0.1 0.32 11.8 0.1 4.6 4 1 0 5 5 1 0 CP12 domain zf-RING_10 PF16685.5 KKK14174.1 - 0.33 11.1 9.0 0.12 12.5 6.0 1.9 2 0 0 2 2 1 0 zinc RING finger of MSL2 zf-UDP PF14569.6 KKK14174.1 - 0.45 10.7 4.4 1.1 9.4 4.4 1.7 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-C2HC_2 PF13913.6 KKK14174.1 - 0.93 9.5 7.3 0.97 9.4 2.7 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Zn_ribbon_17 PF17120.5 KKK14174.1 - 1.2 8.8 4.6 2.3 7.9 4.6 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-Nse PF11789.8 KKK14174.1 - 1.3 8.9 5.2 2.9 7.8 5.2 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit FYVE PF01363.21 KKK14174.1 - 1.5 9.0 11.7 23 5.2 11.7 2.5 1 1 1 2 2 2 0 FYVE zinc finger DUF5340 PF17275.2 KKK14174.1 - 9.2 6.5 9.6 0.34 11.1 0.3 3.4 3 0 0 3 3 3 0 Family of unknown function (DUF5340) Myb_DNA-bind_7 PF15963.5 KKK14175.1 - 1.1e-28 99.0 0.2 1.1e-28 99.0 0.2 2.1 1 1 1 2 2 2 1 Myb DNA-binding like Myb_DNA-binding PF00249.31 KKK14175.1 - 4.6e-06 26.7 0.0 9e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain SARAF PF06682.12 KKK14176.1 - 2e-66 224.9 0.0 2.7e-66 224.5 0.0 1.1 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis GIDA PF01134.22 KKK14177.1 - 1e-153 512.1 0.0 1.3e-153 511.8 0.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc PF13932.6 KKK14177.1 - 4.3e-67 226.4 0.1 5.9e-67 225.9 0.1 1.2 1 0 0 1 1 1 1 GidA associated domain Pyr_redox_2 PF07992.14 KKK14177.1 - 5.1e-06 25.9 0.4 9e-06 25.1 0.4 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KKK14177.1 - 5.4e-06 26.0 1.1 8.7e-06 25.3 1.1 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 KKK14177.1 - 0.00069 19.0 0.2 0.0021 17.4 0.2 1.7 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 KKK14177.1 - 0.0019 17.4 1.7 0.0019 17.4 1.7 1.9 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 KKK14177.1 - 0.019 13.7 0.6 0.17 10.6 0.5 2.2 2 0 0 2 2 2 0 HI0933-like protein Lycopene_cycl PF05834.12 KKK14177.1 - 0.047 12.7 0.2 0.098 11.7 0.2 1.5 1 1 0 1 1 1 0 Lycopene cyclase protein DAO PF01266.24 KKK14177.1 - 0.2 11.2 4.1 4.1 6.9 0.0 2.7 3 0 0 3 3 3 0 FAD dependent oxidoreductase Gti1_Pac2 PF09729.9 KKK14178.1 - 8.2e-63 211.8 0.0 2.2e-62 210.4 0.0 1.6 2 0 0 2 2 2 1 Gti1/Pac2 family AMPK1_CBM PF16561.5 KKK14179.1 - 3.7e-29 100.8 0.1 6.2e-29 100.0 0.1 1.4 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase ABC1 PF03109.16 KKK14180.1 - 4.1e-33 114.1 0.0 2.3e-32 111.7 0.0 2.3 3 0 0 3 3 3 1 ABC1 family UreF PF01730.16 KKK14181.1 - 1.4e-23 84.0 0.2 2.1e-23 83.4 0.2 1.2 1 0 0 1 1 1 1 UreF Sugarporin_N PF11471.8 KKK14181.1 - 0.088 12.8 0.7 0.088 12.8 0.7 2.2 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension EPL1 PF10513.9 KKK14182.1 - 3.5e-21 76.2 0.5 3.5e-21 76.2 0.5 2.9 2 1 1 3 3 3 1 Enhancer of polycomb-like A_deaminase_N PF08451.11 KKK14182.1 - 6 7.2 7.9 3.3 8.1 0.7 3.1 3 0 0 3 3 3 0 Adenosine/AMP deaminase N-terminal EF-hand_1 PF00036.32 KKK14183.1 - 1.1e-27 93.5 13.8 6.5e-08 31.6 0.8 4.4 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KKK14183.1 - 1.5e-21 76.6 9.2 4.4e-13 49.5 1.9 2.6 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KKK14183.1 - 1e-20 71.8 9.0 1.4e-05 24.6 0.1 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 KKK14183.1 - 1e-17 62.8 11.8 5.9e-06 25.5 0.4 4.4 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 KKK14183.1 - 4.3e-13 48.9 13.2 0.00018 21.3 0.7 4.2 3 2 1 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KKK14183.1 - 5.2e-07 30.0 0.0 0.0046 17.3 0.1 2.3 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 KKK14183.1 - 0.00082 19.3 11.6 0.57 10.2 0.5 4.1 1 1 3 4 4 4 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 KKK14183.1 - 0.03 14.6 0.3 0.98 9.8 0.1 2.8 2 1 1 3 3 3 0 EF-hand domain Ribosomal_S9 PF00380.19 KKK14185.1 - 2.1e-40 138.0 0.3 3.4e-40 137.3 0.3 1.3 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Mannosyl_trans3 PF11051.8 KKK14186.1 - 1.6e-63 214.7 0.0 4.9e-37 127.8 0.0 2.1 1 1 1 2 2 2 2 Mannosyltransferase putative SET PF00856.28 KKK14187.1 - 2.1e-22 80.3 0.0 4.7e-22 79.2 0.0 1.6 2 0 0 2 2 2 1 SET domain Rubis-subs-bind PF09273.11 KKK14187.1 - 1.7e-12 48.2 1.6 1.7e-12 48.2 1.6 1.7 2 0 0 2 2 2 1 Rubisco LSMT substrate-binding LEM PF03020.15 KKK14187.1 - 0.0029 17.1 0.1 0.0085 15.6 0.1 1.8 1 0 0 1 1 1 1 LEM domain EF1G PF00647.19 KKK14188.1 - 2.9e-43 146.3 0.1 5.1e-43 145.5 0.1 1.4 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.25 KKK14188.1 - 2.4e-14 53.3 0.0 7.4e-14 51.7 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KKK14188.1 - 2.9e-11 43.6 0.1 9.5e-11 41.9 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KKK14188.1 - 9.9e-09 35.1 0.3 6.5e-08 32.5 0.0 2.4 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KKK14188.1 - 3.3e-06 27.2 0.0 9.2e-06 25.8 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KKK14188.1 - 0.0066 16.8 0.0 0.015 15.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain OAD_gamma PF04277.13 KKK14188.1 - 1.9 9.2 6.3 4.3 8.0 6.3 1.6 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain MMM1 PF10296.9 KKK14189.1 - 9.1e-133 442.4 0.0 1.1e-132 442.1 0.0 1.0 1 0 0 1 1 1 1 Maintenance of mitochondrial morphology protein 1 ARD PF03079.14 KKK14190.1 - 1.1e-44 152.3 0.3 1.3e-44 152.1 0.3 1.0 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.11 KKK14190.1 - 4.9e-10 39.0 0.0 8.5e-10 38.2 0.0 1.4 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 KKK14190.1 - 5.9e-07 29.5 0.0 8.7e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain Gln-synt_N PF03951.19 KKK14205.1 - 9.2e-07 28.5 0.0 1e-06 28.4 0.0 1.0 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain WD40 PF00400.32 KKK14245.1 - 2.4e-13 50.3 7.8 4.4e-05 24.2 0.0 5.3 5 0 0 5 5 5 3 WD domain, G-beta repeat Sad1_UNC PF07738.13 KKK14261.1 - 1.9e-30 105.6 0.0 3.6e-30 104.7 0.0 1.5 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal CEP63 PF17045.5 KKK14261.1 - 0.23 11.3 6.6 0.48 10.3 6.6 1.4 1 0 0 1 1 1 0 Centrosomal protein of 63 kDa Pkinase PF00069.25 KKK14262.1 - 1.4e-54 185.3 0.0 1.9e-54 184.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK14262.1 - 1.8e-31 109.4 0.0 2.4e-31 108.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KKK14262.1 - 1.2e-09 37.9 0.0 9.5e-07 28.4 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 KKK14262.1 - 0.023 14.1 0.0 0.039 13.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family MMR_HSR1 PF01926.23 KKK14263.1 - 7.9e-16 58.2 0.1 4.7e-14 52.4 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KKK14263.1 - 8.8e-08 31.8 0.2 2.1e-05 24.1 0.0 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KKK14263.1 - 2.2e-05 24.4 0.0 0.0079 16.1 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase Dynamin_N PF00350.23 KKK14263.1 - 0.0028 17.7 5.3 0.16 12.0 0.4 3.5 3 1 0 3 3 3 2 Dynamin family AIG1 PF04548.16 KKK14263.1 - 0.009 15.4 0.0 0.019 14.3 0.0 1.5 1 0 0 1 1 1 1 AIG1 family cobW PF02492.19 KKK14263.1 - 0.18 11.4 0.5 1.2 8.7 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Acyl-CoA_dh_1 PF00441.24 KKK14264.1 - 4.1e-28 98.5 1.2 6.9e-28 97.7 1.2 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KKK14264.1 - 4.6e-19 68.4 0.0 7.9e-19 67.7 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Spo12 PF05032.12 KKK14264.1 - 1.3e-15 57.0 1.4 3.1e-15 55.8 1.4 1.7 1 0 0 1 1 1 1 Spo12 family Acyl-CoA_dh_N PF02771.16 KKK14264.1 - 2.3e-12 47.5 0.0 5.5e-12 46.3 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 KKK14264.1 - 8.6e-12 45.5 2.6 1.4e-11 44.8 2.6 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain FAM110_C PF14160.6 KKK14264.1 - 0.06 14.4 0.4 0.11 13.5 0.4 1.4 1 0 0 1 1 1 0 Centrosome-associated C terminus LTV PF04180.14 KKK14265.1 - 4e-124 415.2 8.3 4.5e-124 415.1 8.3 1.0 1 0 0 1 1 1 1 Low temperature viability protein Pex26 PF07163.12 KKK14265.1 - 0.018 14.4 0.0 0.028 13.7 0.0 1.2 1 0 0 1 1 1 0 Pex26 protein DGF-1_C PF11040.8 KKK14265.1 - 1.1 9.3 8.3 0.2 11.6 1.2 3.1 3 1 0 3 3 3 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus Pep3_Vps18 PF05131.14 KKK14266.1 - 1.4e-45 154.8 0.2 4e-45 153.3 0.0 1.9 2 0 0 2 2 2 1 Pep3/Vps18/deep orange family Clathrin PF00637.20 KKK14266.1 - 2.2e-10 40.6 4.1 8.8e-05 22.4 0.0 3.6 3 0 0 3 3 3 2 Region in Clathrin and VPS DUF2175 PF09943.9 KKK14266.1 - 0.00014 22.0 0.3 0.19 12.0 0.0 2.7 2 0 0 2 2 2 2 Uncharacterized protein conserved in archaea (DUF2175) Zn_ribbon_17 PF17120.5 KKK14266.1 - 0.00019 21.0 0.1 0.00039 20.0 0.1 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 KKK14266.1 - 0.0044 16.9 0.3 0.011 15.7 0.3 1.6 1 0 0 1 1 1 1 zinc-RING finger domain Vps39_2 PF10367.9 KKK14266.1 - 0.008 16.6 0.0 0.022 15.2 0.0 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 zf-RING_11 PF17123.5 KKK14266.1 - 0.0083 15.8 4.4 0.028 14.2 4.4 1.9 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KKK14266.1 - 0.0084 15.9 0.6 0.0084 15.9 0.6 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KKK14266.1 - 0.04 14.3 1.0 0.11 12.9 1.0 1.7 1 0 0 1 1 1 0 Ring finger domain zf-RING_UBOX PF13445.6 KKK14266.1 - 0.042 13.9 0.1 0.11 12.5 0.1 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-rbx1 PF12678.7 KKK14266.1 - 0.11 12.8 0.3 0.45 10.8 0.4 1.9 2 0 0 2 2 1 0 RING-H2 zinc finger domain zf-C3H2C3 PF17122.5 KKK14266.1 - 6.6 6.9 5.3 0.98 9.5 1.0 1.9 2 0 0 2 2 2 0 Zinc-finger UCH PF00443.29 KKK14267.1 - 1.5e-14 54.2 0.0 3.4e-14 53.0 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KKK14267.1 - 3.5e-14 53.1 0.0 1.3e-06 28.2 0.0 2.3 1 1 1 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase EnY2 PF10163.9 KKK14267.1 - 0.013 15.8 0.0 0.035 14.5 0.0 1.7 1 0 0 1 1 1 0 Transcription factor e(y)2 Ribosomal_L5_C PF00673.21 KKK14268.1 - 2.9e-31 107.5 0.0 6.5e-31 106.4 0.0 1.6 2 0 0 2 2 2 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 KKK14268.1 - 8.1e-07 29.3 0.1 1.6e-06 28.3 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L5 Septin PF00735.18 KKK14278.1 - 1.3e-10 41.1 0.0 1.5e-07 31.0 0.0 2.1 2 0 0 2 2 2 2 Septin ATP_bind_1 PF03029.17 KKK14278.1 - 0.012 15.4 0.0 0.023 14.5 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_16 PF13191.6 KKK14278.1 - 0.031 14.7 0.0 0.11 12.8 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain AAA_33 PF13671.6 KKK14278.1 - 0.052 13.7 0.0 0.14 12.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KKK14278.1 - 0.076 12.5 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_29 PF13555.6 KKK14278.1 - 0.078 12.7 0.1 0.27 11.0 0.1 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_24 PF13479.6 KKK14278.1 - 0.079 12.7 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 KKK14278.1 - 0.079 13.4 0.0 0.15 12.5 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 KKK14278.1 - 0.08 12.3 0.0 0.2 11.0 0.0 1.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_19 PF13245.6 KKK14278.1 - 0.12 12.7 0.0 0.28 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 KKK14278.1 - 0.13 11.3 0.0 0.26 10.3 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein RsgA_GTPase PF03193.16 KKK14278.1 - 0.17 11.8 0.1 1.8 8.5 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase G-alpha PF00503.20 KKK14278.1 - 0.19 10.9 0.0 0.35 10.0 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit ABC_tran PF00005.27 KKK14278.1 - 0.19 12.3 0.0 0.66 10.5 0.0 1.9 2 0 0 2 2 2 0 ABC transporter HSP90 PF00183.18 KKK14279.1 - 3.8e-222 738.8 33.2 4.9e-222 738.4 33.2 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 KKK14279.1 - 6.1e-15 55.7 0.1 1.1e-14 54.8 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KKK14279.1 - 1.5e-09 37.8 0.1 1.5e-09 37.8 0.1 2.5 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase LOH1CR12 PF10158.9 KKK14279.1 - 0.045 13.8 0.4 0.25 11.4 0.2 2.4 2 0 0 2 2 2 0 Tumour suppressor protein Rad54_N PF08658.10 KKK14279.1 - 0.45 10.6 9.7 0.43 10.7 0.2 2.8 2 0 0 2 2 2 0 Rad54 N terminal DUF1676 PF07898.13 KKK14279.1 - 1 9.3 5.1 0.63 10.1 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1676) Cofac_haem_bdg PF04187.13 KKK14279.1 - 1.2 9.1 4.6 2.6 8.0 0.0 2.9 3 1 1 4 4 4 0 Haem-binding uptake, Tiki superfamily, ChaN NTF2 PF02136.20 KKK14280.1 - 4.6e-27 95.0 0.7 7.5e-27 94.3 0.7 1.4 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.22 KKK14280.1 - 2.6e-09 36.8 0.1 4.6e-09 36.0 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KKK14280.1 - 0.12 12.3 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 Occluded RNA-recognition motif Response_reg PF00072.24 KKK14292.1 - 1e-19 70.7 0.0 3.8e-13 49.6 0.0 2.3 2 0 0 2 2 2 2 Response regulator receiver domain SH3_1 PF00018.28 KKK14293.1 - 4e-10 39.1 0.1 8.1e-10 38.2 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KKK14293.1 - 3.3e-06 26.7 0.0 6.7e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 KKK14293.1 - 1.6e-05 24.7 0.0 2.9e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Herpes_LMP1 PF05297.11 KKK14293.1 - 0.016 14.4 3.1 0.033 13.4 0.1 2.2 2 0 0 2 2 2 0 Herpesvirus latent membrane protein 1 (LMP1) SH3_10 PF17902.1 KKK14293.1 - 0.13 12.4 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 SH3 domain DUF2069 PF09842.9 KKK14293.1 - 0.2 11.8 6.0 0.6 10.3 3.8 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2069) TMEM220 PF15071.6 KKK14293.1 - 2.5 8.9 5.9 4 8.2 5.1 1.9 1 1 0 1 1 1 0 Transmembrane family 220, helix PQ-loop PF04193.14 KKK14294.1 - 2.8e-18 65.4 0.6 2.8e-18 65.4 0.6 3.1 3 1 0 3 3 3 1 PQ loop repeat Vpu PF00558.19 KKK14294.1 - 0.096 12.5 3.3 0.22 11.3 0.3 2.3 2 0 0 2 2 2 0 Vpu protein Syndecan PF01034.20 KKK14294.1 - 0.26 11.2 1.8 4.5 7.3 0.0 3.1 3 0 0 3 3 3 0 Syndecan domain CUB_2 PF02408.20 KKK14297.1 - 0.062 13.1 0.1 0.12 12.2 0.1 1.4 1 0 0 1 1 1 0 CUB-like domain DUF2235 PF09994.9 KKK14298.1 - 2.2e-78 263.5 0.0 2.8e-78 263.2 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) MMR_HSR1 PF01926.23 KKK14299.1 - 1.7e-06 28.1 0.1 2.3e-05 24.4 0.1 2.9 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KKK14299.1 - 4.5e-05 23.9 0.1 0.0014 19.1 0.0 3.1 3 0 0 3 3 3 1 AAA ATPase domain AIG1 PF04548.16 KKK14299.1 - 0.00043 19.7 0.0 0.65 9.3 0.0 2.7 2 0 0 2 2 2 2 AIG1 family RsgA_GTPase PF03193.16 KKK14299.1 - 0.00098 19.1 0.1 0.0059 16.5 0.0 2.3 2 1 0 2 2 1 1 RsgA GTPase AAA_29 PF13555.6 KKK14299.1 - 0.0026 17.4 0.0 0.0063 16.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_24 PF13479.6 KKK14299.1 - 0.0039 16.9 0.1 0.041 13.6 0.0 2.7 3 0 0 3 3 3 1 AAA domain TniB PF05621.11 KKK14299.1 - 0.0049 16.3 0.0 0.018 14.5 0.0 1.9 1 0 0 1 1 1 1 Bacterial TniB protein FtsK_SpoIIIE PF01580.18 KKK14299.1 - 0.012 15.0 0.0 0.029 13.7 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family T2SSE PF00437.20 KKK14299.1 - 0.015 14.4 0.0 0.033 13.2 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein GTP_EFTU PF00009.27 KKK14299.1 - 0.019 14.5 0.0 0.061 12.9 0.0 1.9 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain Septin PF00735.18 KKK14299.1 - 0.019 14.2 0.2 0.082 12.2 0.2 2.1 1 1 0 1 1 1 0 Septin Dynamin_N PF00350.23 KKK14299.1 - 0.023 14.8 4.7 2.7 8.0 0.0 3.6 3 0 0 3 3 3 0 Dynamin family AAA_23 PF13476.6 KKK14299.1 - 0.045 14.3 0.0 0.045 14.3 0.0 3.0 2 1 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KKK14299.1 - 0.055 14.0 2.6 0.47 11.0 0.0 3.1 3 0 0 3 3 3 0 ABC transporter YfbU PF03887.14 KKK14299.1 - 0.055 13.5 0.6 0.16 12.0 0.6 1.7 1 0 0 1 1 1 0 YfbU domain Sigma54_activat PF00158.26 KKK14299.1 - 0.069 12.9 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Ca_bind_SSO6904 PF18249.1 KKK14299.1 - 0.077 13.4 0.6 0.23 11.8 0.1 2.1 2 0 0 2 2 1 0 Calcium binding protein SSO6904 NACHT PF05729.12 KKK14299.1 - 0.1 12.5 0.1 1.4 8.8 0.0 2.9 3 0 0 3 3 3 0 NACHT domain AAA_22 PF13401.6 KKK14299.1 - 0.12 12.6 0.1 1.2 9.4 0.0 2.8 3 0 0 3 3 1 0 AAA domain RNA_helicase PF00910.22 KKK14299.1 - 0.13 12.7 0.1 0.87 10.0 0.0 2.4 2 0 0 2 2 2 0 RNA helicase DUF87 PF01935.17 KKK14299.1 - 0.18 11.9 0.0 0.18 11.9 0.0 3.7 3 1 0 3 3 3 0 Helicase HerA, central domain G-alpha PF00503.20 KKK14299.1 - 0.21 10.7 3.6 0.25 10.5 0.0 2.6 3 1 0 3 3 3 0 G-protein alpha subunit Snf7 PF03357.21 KKK14299.1 - 0.3 10.7 9.2 0.025 14.2 3.9 2.0 2 0 0 2 2 2 0 Snf7 UPF0231 PF06062.11 KKK14299.1 - 0.83 9.9 8.6 0.18 12.1 1.1 2.9 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0231) Sugar_tr PF00083.24 KKK14300.1 - 1.7e-82 277.7 25.7 1.9e-82 277.5 25.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKK14300.1 - 4.2e-39 134.5 51.5 1.1e-36 126.6 28.9 1.4 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KKK14300.1 - 4.1e-06 25.6 6.9 4.1e-06 25.6 6.9 2.4 2 0 0 2 2 2 1 MFS/sugar transport protein TRI12 PF06609.13 KKK14300.1 - 1.3e-05 23.9 7.7 2.9e-05 22.7 4.4 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) GTP_EFTU_D4 PF14578.6 KKK14300.1 - 0.092 12.7 0.3 11 6.0 0.0 2.9 3 0 0 3 3 3 0 Elongation factor Tu domain 4 MFS_3 PF05977.13 KKK14300.1 - 2 6.7 14.0 0.062 11.7 3.1 2.7 3 1 1 4 4 4 0 Transmembrane secretion effector Fungal_trans PF04082.18 KKK14301.1 - 1.8e-10 40.3 0.0 3.5e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 KKK14301.1 - 1.2e-07 31.7 14.6 0.0014 19.0 5.4 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KKK14301.1 - 1.1e-06 28.8 17.6 6.8e-06 26.3 5.2 3.7 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KKK14301.1 - 0.00046 20.8 17.8 0.028 15.2 1.6 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KKK14301.1 - 0.0027 17.7 13.3 0.16 12.0 1.9 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2HC_2 PF13913.6 KKK14301.1 - 0.008 16.1 1.2 0.008 16.1 1.2 2.1 2 0 0 2 2 2 1 zinc-finger of a C2HC-type zf-C2H2_8 PF15909.5 KKK14301.1 - 0.067 13.5 4.0 0.38 11.1 4.4 2.1 2 0 0 2 2 2 0 C2H2-type zinc ribbon FAD_binding_3 PF01494.19 KKK14302.1 - 3.1e-72 243.7 0.0 4.6e-72 243.2 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KKK14302.1 - 0.00094 18.5 0.0 0.0074 15.6 0.0 2.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KKK14302.1 - 0.0023 18.1 0.0 0.0059 16.8 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KKK14302.1 - 0.0063 15.8 0.0 0.014 14.7 0.0 1.5 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 KKK14302.1 - 0.0093 14.7 0.0 0.016 13.9 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.6 KKK14302.1 - 0.012 14.9 0.0 0.02 14.1 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KKK14302.1 - 0.016 14.3 0.0 0.23 10.5 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain DAO PF01266.24 KKK14302.1 - 0.031 13.9 0.0 0.16 11.5 0.0 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox PF00070.27 KKK14302.1 - 0.037 14.6 0.0 0.11 13.1 0.0 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KKK14302.1 - 0.086 12.2 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KKK14302.1 - 0.13 12.3 0.1 0.59 10.1 0.0 2.0 2 0 0 2 2 2 0 FAD-NAD(P)-binding FSA_C PF10479.9 KKK14303.1 - 1 7.4 22.6 1.5 6.9 22.6 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Dicty_REP PF05086.12 KKK14303.1 - 2.6 5.9 8.0 3.1 5.7 8.0 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Herpes_capsid PF06112.11 KKK14303.1 - 5.9 6.9 14.6 13 5.8 14.6 1.7 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Ysc84 PF04366.12 KKK14304.1 - 5.7e-47 158.7 0.1 8.5e-47 158.1 0.1 1.3 1 0 0 1 1 1 1 Las17-binding protein actin regulator Methyltransf_25 PF13649.6 KKK14305.1 - 1.8e-19 70.2 0.0 1.4e-18 67.4 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KKK14305.1 - 4e-17 62.7 0.0 1.1e-16 61.3 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KKK14305.1 - 5.3e-12 45.9 0.0 6.8e-12 45.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KKK14305.1 - 6.3e-10 39.1 0.0 1e-09 38.4 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KKK14305.1 - 6.6e-09 36.4 0.0 1.7e-08 35.1 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.20 KKK14305.1 - 4.9e-06 26.0 0.0 6e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.14 KKK14305.1 - 0.0051 16.4 0.0 0.0086 15.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Pox_MCEL PF03291.16 KKK14305.1 - 0.022 13.9 0.0 0.11 11.5 0.0 1.9 1 1 1 2 2 2 0 mRNA capping enzyme MetW PF07021.12 KKK14305.1 - 0.032 13.8 0.0 0.053 13.1 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltr_RsmB-F PF01189.17 KKK14305.1 - 0.05 13.2 0.0 6.1 6.4 0.0 2.1 2 0 0 2 2 2 0 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 KKK14305.1 - 0.073 13.2 0.0 1.1 9.3 0.0 2.1 1 1 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_9 PF08003.11 KKK14305.1 - 0.17 10.8 0.0 0.3 10.0 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1698) FAD_binding_4 PF01565.23 KKK14308.1 - 7.6e-24 84.0 0.2 1.2e-23 83.4 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KKK14308.1 - 0.00045 20.3 0.0 0.00093 19.3 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like Mid2 PF04478.12 KKK14309.1 - 0.0027 17.6 0.0 0.0075 16.1 0.0 1.8 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor Phage_fiber PF03335.13 KKK14309.1 - 0.074 13.2 1.0 0.23 11.7 1.0 1.9 1 0 0 1 1 1 0 Phage tail fibre repeat Pro_isomerase PF00160.21 KKK14310.1 - 3.8e-50 170.2 0.2 4.4e-50 170.0 0.2 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD CBM_4_9 PF02018.17 KKK14312.1 - 2.7e-10 40.6 0.1 3.2e-10 40.4 0.1 1.0 1 0 0 1 1 1 1 Carbohydrate binding domain Sugar_tr PF00083.24 KKK14313.1 - 3.8e-37 128.2 25.7 5.2e-25 88.2 11.9 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KKK14313.1 - 4.4e-19 68.6 34.2 1.6e-18 66.8 34.2 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily PhyH PF05721.13 KKK14314.1 - 4.6e-28 98.9 0.0 5.8e-28 98.6 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_3 PF13640.6 KKK14314.1 - 0.0023 18.8 0.0 0.0057 17.5 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_5 PF13759.6 KKK14314.1 - 0.022 15.2 0.0 0.049 14.0 0.0 1.7 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase Pico_P2B PF01552.17 KKK14315.1 - 0.21 11.8 0.9 7 6.9 0.2 2.3 2 0 0 2 2 2 0 Picornavirus 2B protein Aegerolysin PF06355.13 KKK14316.1 - 1.3e-36 125.6 0.4 1.4e-36 125.4 0.4 1.0 1 0 0 1 1 1 1 Aegerolysin Fic PF02661.18 KKK14317.1 - 0.14 13.1 0.1 0.28 12.1 0.1 1.5 1 0 0 1 1 1 0 Fic/DOC family Peptidase_S10 PF00450.22 KKK14319.1 - 1.3e-102 344.4 7.1 1.6e-102 344.1 7.1 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase PHO4 PF01384.20 KKK14320.1 - 1.5e-116 389.2 11.0 1.7e-116 389.0 11.0 1.0 1 0 0 1 1 1 1 Phosphate transporter family Aldo_ket_red PF00248.21 KKK14321.1 - 6e-43 147.1 0.0 5.8e-41 140.6 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Reoviridae_Vp9 PF08978.10 KKK14321.1 - 0.073 12.2 0.0 0.11 11.7 0.0 1.1 1 0 0 1 1 1 0 Reoviridae VP9 GMC_oxred_C PF05199.13 KKK14322.1 - 3.7e-10 40.5 0.0 1.3e-09 38.7 0.0 2.0 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_N PF00732.19 KKK14322.1 - 3.5e-07 29.9 0.0 7.4e-07 28.8 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KKK14322.1 - 0.00038 19.7 0.7 0.00061 19.0 0.7 1.3 1 0 0 1 1 1 1 FAD binding domain Abhydrolase_1 PF00561.20 KKK14322.1 - 0.00089 19.0 0.0 0.3 10.7 0.0 2.5 2 0 0 2 2 2 2 alpha/beta hydrolase fold NAD_binding_8 PF13450.6 KKK14322.1 - 0.0024 18.1 0.5 0.0079 16.4 0.5 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KKK14322.1 - 0.013 14.7 0.0 0.023 13.9 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KKK14322.1 - 0.015 15.8 0.0 0.039 14.5 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Glyco_trans_4_2 PF13477.6 KKK14322.1 - 0.13 12.3 0.0 0.34 10.9 0.0 1.7 1 0 0 1 1 1 0 Glycosyl transferase 4-like FAD_oxidored PF12831.7 KKK14322.1 - 0.15 11.4 3.1 0.24 10.7 3.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Glyco_transf_56 PF07429.11 KKK14322.1 - 0.22 10.6 0.0 0.37 9.9 0.0 1.2 1 0 0 1 1 1 0 4-alpha-L-fucosyltransferase glycosyl transferase group 56 HemolysinCabind PF00353.19 KKK14322.1 - 2 8.5 6.1 5.1 7.2 6.1 1.7 1 0 0 1 1 1 0 RTX calcium-binding nonapeptide repeat (4 copies) cobW PF02492.19 KKK14323.1 - 6.7e-48 162.6 5.3 1.2e-36 126.0 1.0 2.2 1 1 1 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 KKK14323.1 - 3.5e-21 74.9 0.3 1.8e-16 59.8 0.0 2.8 3 0 0 3 3 3 2 Cobalamin synthesis protein cobW C-terminal domain MobB PF03205.14 KKK14323.1 - 0.0021 18.0 0.1 0.0041 17.0 0.1 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.6 KKK14323.1 - 0.0097 16.3 0.2 0.028 14.8 0.2 2.0 1 1 0 1 1 1 1 AAA ATPase domain TsaE PF02367.17 KKK14323.1 - 0.014 15.4 0.1 0.03 14.3 0.1 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 KKK14323.1 - 0.014 15.6 0.1 0.043 14.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain MeaB PF03308.16 KKK14323.1 - 0.016 14.2 0.6 0.46 9.4 0.1 2.5 2 1 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB PTPRCAP PF15713.5 KKK14323.1 - 0.022 15.1 1.1 0.022 15.1 1.1 2.0 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated Viral_helicase1 PF01443.18 KKK14323.1 - 0.035 13.8 0.1 0.084 12.6 0.1 1.7 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase ATPase_2 PF01637.18 KKK14323.1 - 0.069 13.1 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_18 PF13238.6 KKK14323.1 - 0.085 13.4 0.3 0.32 11.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 KKK14323.1 - 0.091 13.0 0.1 0.21 11.8 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KKK14323.1 - 0.11 12.3 0.0 0.29 10.9 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Zeta_toxin PF06414.12 KKK14323.1 - 0.18 11.1 0.0 0.32 10.2 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin T2SSE PF00437.20 KKK14323.1 - 0.21 10.6 1.7 0.18 10.8 0.2 1.6 2 0 0 2 2 2 0 Type II/IV secretion system protein Importin_rep_6 PF18829.1 KKK14323.1 - 0.5 10.5 6.7 9.1 6.5 0.0 2.8 2 0 0 2 2 2 0 Importin repeat 6 HHH_5 PF14520.6 KKK14324.1 - 0.0001 22.8 0.0 0.25 12.0 0.0 2.3 2 0 0 2 2 2 2 Helix-hairpin-helix domain UPF0181 PF03701.14 KKK14324.1 - 0.17 11.6 0.1 0.29 10.8 0.1 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0181) HD PF01966.22 KKK14325.1 - 2.1e-07 31.2 0.0 2.8e-07 30.8 0.0 1.4 1 1 0 1 1 1 1 HD domain MIOX PF05153.15 KKK14325.1 - 0.0051 16.4 0.0 0.0074 15.9 0.0 1.2 1 0 0 1 1 1 1 Myo-inositol oxygenase HDOD PF08668.12 KKK14325.1 - 0.025 14.0 0.0 0.038 13.5 0.0 1.3 1 0 0 1 1 1 0 HDOD domain HD_6 PF18019.1 KKK14325.1 - 0.054 13.6 0.0 0.061 13.4 0.0 1.2 1 0 0 1 1 1 0 HD domain Leucyl-specific PF14795.6 KKK14325.1 - 0.17 12.0 0.6 3.2 7.9 0.0 2.9 4 0 0 4 4 4 0 Leucine-tRNA synthetase-specific domain Kelch_4 PF13418.6 KKK14346.1 - 8.8e-17 60.8 1.6 4.4e-07 29.8 0.0 5.3 4 1 0 4 4 4 2 Galactose oxidase, central domain Kelch_5 PF13854.6 KKK14346.1 - 9.9e-16 57.3 0.2 2.5e-05 24.2 0.0 4.5 3 1 0 3 3 3 3 Kelch motif Kelch_3 PF13415.6 KKK14346.1 - 5.8e-13 48.8 3.5 1e-06 28.9 0.0 5.8 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_1 PF01344.25 KKK14346.1 - 3.8e-12 45.6 0.0 0.0049 16.4 0.0 4.4 3 1 0 3 3 3 3 Kelch motif Kelch_2 PF07646.15 KKK14346.1 - 2.6e-10 39.8 2.2 0.002 18.1 0.0 4.6 3 1 0 3 3 3 3 Kelch motif Kelch_6 PF13964.6 KKK14346.1 - 8.5e-10 38.6 8.5 0.028 14.7 0.7 5.8 4 1 1 5 5 5 3 Kelch motif AhpC-TSA PF00578.21 KKK14347.1 - 8e-34 116.2 0.0 1.5e-33 115.3 0.0 1.4 1 1 1 2 2 2 1 AhpC/TSA family 1-cysPrx_C PF10417.9 KKK14347.1 - 2.2e-16 59.4 0.2 3.6e-16 58.7 0.2 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Redoxin PF08534.10 KKK14347.1 - 5.5e-13 48.9 0.0 7.2e-13 48.5 0.0 1.1 1 0 0 1 1 1 1 Redoxin EVE PF01878.18 KKK14348.1 - 7.2e-46 155.8 0.0 1.9e-44 151.2 0.0 2.2 1 1 0 1 1 1 1 EVE domain AT_hook PF02178.19 KKK14348.1 - 0.0087 15.8 36.4 0.098 12.6 6.4 4.2 4 0 0 4 4 4 3 AT hook motif RFX5_DNA_bdg PF14621.6 KKK14348.1 - 5.7 6.6 28.1 1.1 9.0 4.1 3.3 1 1 2 3 3 3 0 RFX5 DNA-binding domain CTP_transf_like PF01467.26 KKK14349.1 - 2e-05 24.8 0.1 0.00048 20.4 0.1 2.8 2 1 0 2 2 2 1 Cytidylyltransferase-like SGL PF08450.12 KKK14350.1 - 7.6e-81 271.3 0.0 9.5e-81 271.0 0.0 1.1 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Aldedh PF00171.22 KKK14351.1 - 4.7e-185 615.5 0.4 5.3e-185 615.3 0.4 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 KKK14351.1 - 0.057 12.9 0.0 0.16 11.4 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1487) Pkinase PF00069.25 KKK14358.1 - 2.6e-19 69.6 0.0 3.3e-19 69.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK14358.1 - 1.3e-15 57.4 0.0 1.7e-15 57.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KKK14358.1 - 0.0015 17.9 0.0 0.0023 17.3 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KKK14358.1 - 0.002 17.5 0.0 0.0045 16.4 0.0 1.5 1 1 0 1 1 1 1 Kinase-like MFS_1 PF07690.16 KKK14359.1 - 1e-05 24.7 2.8 1.1e-05 24.5 2.8 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KKK14359.1 - 0.00058 18.8 0.0 0.00071 18.5 0.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter Pkinase PF00069.25 KKK14360.1 - 9e-73 244.9 0.0 1.4e-72 244.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK14360.1 - 1.1e-37 129.8 0.0 3.1e-37 128.3 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KKK14360.1 - 0.0011 18.3 0.8 2.4 7.4 0.0 3.0 3 0 0 3 3 3 2 Kinase-like Pkinase_fungal PF17667.1 KKK14360.1 - 0.11 11.2 0.0 0.29 9.9 0.0 1.7 2 0 0 2 2 2 0 Fungal protein kinase Fungal_trans PF04082.18 KKK14362.1 - 9.6e-10 37.9 0.8 1.5e-09 37.3 0.8 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK14362.1 - 1.7e-06 28.0 10.4 3.7e-06 26.9 10.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mst1_SARAH PF11629.8 KKK14362.1 - 0.25 11.4 2.0 22 5.2 0.4 2.6 2 0 0 2 2 2 0 C terminal SARAH domain of Mst1 GRDP-like PF07173.12 KKK14363.1 - 5.6e-18 66.0 2.1 1.1e-13 52.0 0.1 2.6 2 0 0 2 2 2 2 Glycine-rich domain-containing protein-like Pea-VEAacid PF08111.11 KKK14363.1 - 0.77 10.2 3.8 8.4 7.0 0.2 2.7 2 0 0 2 2 2 0 Pea-VEAacid family F-box-like PF12937.7 KKK14365.1 - 0.0033 17.3 0.2 0.0087 15.9 0.2 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KKK14365.1 - 0.0084 16.0 0.4 0.019 14.8 0.4 1.7 1 0 0 1 1 1 1 F-box domain ANAPC4_WD40 PF12894.7 KKK14365.1 - 0.11 12.7 0.0 1.1 9.6 0.0 2.6 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Fungal_trans PF04082.18 KKK14366.1 - 4.6e-15 55.4 0.0 9.5e-15 54.3 0.0 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK14366.1 - 1.6e-06 28.1 7.0 3.6e-06 27.0 7.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Alpha-L-AF_C PF06964.12 KKK14377.1 - 8.8e-27 94.3 0.0 1.4e-26 93.6 0.0 1.4 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminal domain Pectate_lyase PF03211.13 KKK14378.1 - 1.3e-84 282.9 6.5 1.5e-84 282.6 6.5 1.0 1 0 0 1 1 1 1 Pectate lyase MIP PF00230.20 KKK14379.1 - 2.8e-41 141.7 6.7 3.8e-41 141.3 6.7 1.1 1 0 0 1 1 1 1 Major intrinsic protein PP-binding PF00550.25 KKK14380.1 - 6.9e-07 29.5 0.0 2.9e-06 27.5 0.0 1.9 2 0 0 2 2 2 1 Phosphopantetheine attachment site ketoacyl-synt PF00109.26 KKK14381.1 - 2.4e-63 214.1 0.0 1.2e-62 211.8 0.0 2.0 1 1 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 KKK14381.1 - 5.5e-53 179.6 0.1 1.2e-52 178.5 0.1 1.6 1 0 0 1 1 1 1 KR domain ADH_zinc_N_2 PF13602.6 KKK14381.1 - 2.6e-21 77.1 0.0 4.9e-19 69.7 0.0 2.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KKK14381.1 - 1.2e-16 60.8 0.0 4.2e-16 59.1 0.0 1.9 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.12 KKK14381.1 - 2.4e-10 41.0 0.0 8.6e-10 39.2 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.25 KKK14381.1 - 1e-09 38.2 0.0 2.1e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase Methyltransf_23 PF13489.6 KKK14381.1 - 6.1e-08 32.7 0.0 1.2e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain adh_short_C2 PF13561.6 KKK14381.1 - 3.5e-07 30.0 0.0 6.6e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Methyltransf_11 PF08241.12 KKK14381.1 - 7.4e-07 29.7 0.0 3.1e-06 27.7 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KKK14381.1 - 3.8e-06 26.8 0.0 1.1e-05 25.3 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKK14381.1 - 1.5e-05 25.6 0.0 7.6e-05 23.3 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KKK14381.1 - 0.0015 17.9 0.0 0.0038 16.6 0.0 1.6 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Thiolase_N PF00108.23 KKK14381.1 - 0.023 14.1 0.0 0.046 13.1 0.0 1.4 1 0 0 1 1 1 0 Thiolase, N-terminal domain Methyltransf_16 PF10294.9 KKK14381.1 - 0.14 11.8 0.0 0.72 9.6 0.0 2.0 2 0 0 2 2 2 0 Lysine methyltransferase Metallophos PF00149.28 KKK14382.1 - 8.7e-14 52.5 0.0 1.8e-13 51.5 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Lipase_GDSL_2 PF13472.6 KKK14382.1 - 0.052 13.9 0.1 4.1 7.8 0.0 2.9 3 0 0 3 3 3 0 GDSL-like Lipase/Acylhydrolase family RHH_4 PF13467.6 KKK14382.1 - 0.14 12.1 0.0 16 5.4 0.0 3.2 3 0 0 3 3 3 0 Ribbon-helix-helix domain PBP_like_2 PF12849.7 KKK14383.1 - 1e-13 51.6 3.4 1.3e-13 51.3 3.4 1.1 1 0 0 1 1 1 1 PBP superfamily domain Transferase PF02458.15 KKK14384.1 - 1.3e-07 30.7 0.0 0.00069 18.4 0.0 2.1 1 1 1 2 2 2 2 Transferase family MFS_1 PF07690.16 KKK14386.1 - 6.4e-21 74.7 23.5 6.4e-21 74.7 23.5 2.4 1 1 2 3 3 3 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KKK14386.1 - 0.0055 15.6 30.2 0.08 11.8 30.2 2.4 1 1 0 1 1 1 1 Sugar (and other) transporter Peptidase_M56 PF05569.11 KKK14386.1 - 0.12 11.6 1.8 0.19 10.9 0.1 2.0 2 0 0 2 2 2 0 BlaR1 peptidase M56 DUF5336 PF17270.2 KKK14386.1 - 0.55 9.8 0.0 0.55 9.8 0.0 3.7 4 0 0 4 4 4 0 Family of unknown function (DUF5336) Phage_holin_7_1 PF16081.5 KKK14386.1 - 1.4 9.1 7.8 0.13 12.4 0.9 2.5 2 1 0 2 2 2 0 Mycobacterial 2 TMS Phage Holin (M2 Hol) Family OATP PF03137.20 KKK14386.1 - 7 4.8 16.6 0.11 10.7 3.4 2.9 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family GWT1 PF06423.12 KKK14386.1 - 8.9 6.4 8.5 2.9 8.0 0.6 3.1 2 1 1 3 3 3 0 GWT1 E1-E2_ATPase PF00122.20 KKK14387.1 - 1e-36 126.1 1.8 1e-36 126.1 1.8 2.5 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 KKK14387.1 - 3.6e-27 95.2 2.2 3.6e-27 95.2 2.2 2.7 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 KKK14387.1 - 1.3e-17 63.6 0.0 2.6e-17 62.7 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KKK14387.1 - 1.2e-15 58.4 0.0 2.6e-15 57.3 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KKK14387.1 - 8.9e-07 28.5 0.0 3e-06 26.8 0.0 2.0 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KKK14387.1 - 5.4e-05 23.0 0.2 0.00069 19.4 0.1 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase LptF_LptG PF03739.14 KKK14387.1 - 0.036 12.9 2.3 0.076 11.8 2.3 1.5 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG MadL PF03817.13 KKK14387.1 - 0.4 10.7 3.2 1.6 8.7 0.1 2.6 2 0 0 2 2 2 0 Malonate transporter MadL subunit DUF4231 PF14015.6 KKK14387.1 - 2.6 8.6 5.2 5.1 7.6 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) Colicin_V PF02674.16 KKK14387.1 - 3 7.8 8.6 0.27 11.2 0.2 3.0 3 0 0 3 3 3 0 Colicin V production protein HsbA PF12296.8 KKK14388.1 - 3e-22 79.3 11.2 3.5e-22 79.1 10.7 1.4 1 1 0 1 1 1 1 Hydrophobic surface binding protein A Formyl_trans_C PF02911.18 KKK14388.1 - 0.11 12.8 0.0 0.17 12.1 0.0 1.3 1 0 0 1 1 1 0 Formyl transferase, C-terminal domain Cytochrom_B562 PF07361.11 KKK14388.1 - 0.15 12.7 0.1 0.95 10.2 0.0 2.1 2 1 0 2 2 2 0 Cytochrome b562 Sec1 PF00995.23 KKK14389.1 - 1.1e-128 431.1 0.0 1.2e-128 430.8 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Pkinase_C PF00433.24 KKK14389.1 - 0.042 14.6 0.0 0.18 12.5 0.0 2.2 1 0 0 1 1 1 0 Protein kinase C terminal domain zf_CCCH_4 PF18345.1 KKK14390.1 - 6.1e-06 26.1 3.8 1.1e-05 25.3 3.8 1.4 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_4 PF18044.1 KKK14390.1 - 0.00072 19.3 2.3 0.0012 18.6 2.3 1.4 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH PF00642.24 KKK14390.1 - 0.012 15.5 0.7 0.02 14.8 0.7 1.3 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 KKK14390.1 - 0.029 14.8 1.3 0.054 14.0 1.3 1.5 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 KKK14390.1 - 0.054 13.7 0.1 0.17 12.1 0.1 1.9 1 0 0 1 1 1 0 Zinc-finger containing family HORMA PF02301.18 KKK14391.1 - 2.2e-33 115.7 0.1 2.6e-33 115.4 0.1 1.0 1 0 0 1 1 1 1 HORMA domain Arcadin_1 PF18653.1 KKK14391.1 - 0.014 15.4 0.1 3.9 7.6 0.0 2.2 2 0 0 2 2 2 0 Arcadin 1 DUF2660 PF10859.8 KKK14391.1 - 0.027 14.9 0.0 0.084 13.3 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2660) DUF4760 PF15956.5 KKK14391.1 - 0.037 14.1 0.5 0.11 12.6 0.1 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4760) FlaG PF03646.15 KKK14391.1 - 7.2 6.8 10.9 23 5.2 3.3 2.8 2 1 0 2 2 2 0 FlaG protein RNA_pol_Rpb1_1 PF04997.12 KKK14392.1 - 5.6e-85 285.4 0.0 9.2e-85 284.7 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 KKK14392.1 - 2.1e-81 273.2 1.0 3.4e-81 272.6 1.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 KKK14392.1 - 3.3e-71 238.9 0.0 9.7e-71 237.3 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 GTP_EFTU PF00009.27 KKK14392.1 - 3.1e-42 144.3 0.0 4.7e-41 140.5 0.0 2.3 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain LepA_C PF06421.12 KKK14392.1 - 1.5e-39 134.5 1.3 4e-39 133.1 1.3 1.7 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus RNA_pol_Rpb1_3 PF04983.18 KKK14392.1 - 5e-33 114.3 0.0 1.9e-32 112.4 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 KKK14392.1 - 4.8e-27 94.0 0.1 1.2e-26 92.8 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 EFG_C PF00679.24 KKK14392.1 - 8.6e-20 70.6 0.0 3.9e-19 68.5 0.0 2.2 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KKK14392.1 - 3.1e-05 24.3 0.2 0.00013 22.2 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_II PF14492.6 KKK14392.1 - 0.015 15.4 0.0 0.048 13.7 0.0 2.0 1 0 0 1 1 1 0 Elongation Factor G, domain II RF3_C PF16658.5 KKK14392.1 - 0.021 14.7 0.0 0.069 13.0 0.0 1.9 2 0 0 2 2 2 0 Class II release factor RF3, C-terminal domain Ras PF00071.22 KKK14392.1 - 0.16 11.6 0.0 0.79 9.3 0.0 2.1 1 1 1 2 2 2 0 Ras family Aldo_ket_red PF00248.21 KKK14393.1 - 3.4e-33 115.1 0.1 6.7e-17 61.6 0.0 3.1 2 1 1 3 3 3 3 Aldo/keto reductase family DUF1120 PF06551.12 KKK14393.1 - 0.015 15.5 0.0 0.24 11.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1120) BAR PF03114.18 KKK14394.1 - 1.9e-69 234.0 6.2 2.4e-69 233.6 6.2 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.28 KKK14394.1 - 3e-15 55.6 0.0 5.2e-15 54.8 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KKK14394.1 - 1e-12 47.7 0.0 1.8e-12 46.9 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KKK14394.1 - 2.7e-09 36.6 0.0 6.9e-09 35.3 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain CT_C_D PF02682.16 KKK14394.1 - 0.21 11.3 1.0 0.34 10.6 0.4 1.6 2 0 0 2 2 2 0 Carboxyltransferase domain, subdomain C and D BRE1 PF08647.11 KKK14394.1 - 0.29 11.2 9.3 1.6 8.8 0.8 2.8 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase TMPIT PF07851.13 KKK14394.1 - 5.1 6.2 7.6 2.8 7.1 0.2 2.1 1 1 1 2 2 2 0 TMPIT-like protein Aminotran_5 PF00266.19 KKK14395.1 - 2.6e-94 316.2 0.0 3.2e-94 315.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KKK14395.1 - 2.2e-05 23.9 0.1 3.5e-05 23.2 0.1 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 KKK14395.1 - 0.00056 19.3 0.0 0.0012 18.3 0.0 1.5 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.19 KKK14395.1 - 0.0011 17.8 0.0 0.0016 17.2 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Cys_Met_Meta_PP PF01053.20 KKK14395.1 - 0.091 11.3 0.0 0.13 10.7 0.0 1.1 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme DUF3942 PF13078.6 KKK14395.1 - 0.13 12.6 0.1 0.43 10.9 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3942) IDO PF01231.18 KKK14396.1 - 1.2e-140 469.1 0.0 1.4e-140 468.9 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase Epimerase PF01370.21 KKK14397.1 - 1.6e-10 40.9 0.0 1.5e-09 37.7 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KKK14397.1 - 2.7e-07 30.7 0.0 4.6e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 KKK14397.1 - 9.5e-05 21.7 0.4 0.0031 16.7 0.1 2.7 1 1 1 2 2 2 1 Male sterility protein 3Beta_HSD PF01073.19 KKK14397.1 - 9.7e-05 21.5 0.0 0.00032 19.8 0.0 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 KKK14397.1 - 0.002 17.7 0.0 0.003 17.2 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.15 KKK14397.1 - 0.0056 15.8 0.0 0.0087 15.2 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Semialdhyde_dh PF01118.24 KKK14397.1 - 0.031 14.7 0.0 0.055 13.9 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain AA_permease PF00324.21 KKK14398.1 - 2.5e-143 478.1 39.3 2.9e-143 478.0 39.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KKK14398.1 - 2.1e-37 129.0 40.8 2.8e-37 128.6 40.8 1.1 1 0 0 1 1 1 1 Amino acid permease Fungal_trans_2 PF11951.8 KKK14399.1 - 1.7e-06 27.1 0.0 3.3e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK14399.1 - 1.7e-06 28.0 10.9 3.1e-06 27.2 10.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.22 KKK14400.1 - 1.1e-47 162.8 0.0 1.4e-47 162.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 PIG-X PF08320.12 KKK14400.1 - 0.04 13.8 0.0 0.14 12.0 0.0 1.8 2 0 0 2 2 2 0 PIG-X / PBN1 AA_permease_2 PF13520.6 KKK14401.1 - 5.5e-65 219.9 33.9 6.7e-65 219.6 33.9 1.0 1 0 0 1 1 1 1 Amino acid permease MAPEG PF01124.18 KKK14402.1 - 2.8e-15 56.4 2.1 3.7e-15 56.0 2.1 1.1 1 0 0 1 1 1 1 MAPEG family STE2 PF02116.15 KKK14404.1 - 9.8e-103 343.3 16.8 1.2e-102 343.1 16.8 1.0 1 0 0 1 1 1 1 Fungal pheromone mating factor STE2 GPCR DUF3754 PF12576.8 KKK14404.1 - 0.12 12.4 1.5 0.15 12.0 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3754) PufQ PF05398.11 KKK14404.1 - 0.37 11.0 2.8 11 6.2 0.1 2.4 1 1 1 2 2 2 0 PufQ cytochrome subunit APH PF01636.23 KKK14405.1 - 0.036 14.0 0.2 0.08 12.8 0.1 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family Beta_helix PF13229.6 KKK14406.1 - 1e-08 35.2 9.3 2.4e-08 34.0 5.2 2.4 1 1 1 2 2 2 2 Right handed beta helix region Chondroitinas_B PF14592.6 KKK14406.1 - 0.0095 14.9 0.0 0.016 14.2 0.0 1.3 1 0 0 1 1 1 1 Chondroitinase B DUF1565 PF07602.11 KKK14406.1 - 0.018 14.4 0.2 0.036 13.4 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1565) DIOX_N PF14226.6 KKK14407.1 - 5.4e-37 127.1 0.0 1.5e-33 116.1 0.0 2.2 2 0 0 2 2 2 2 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KKK14407.1 - 1.1e-14 54.8 0.0 2e-14 53.9 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Cu_amine_oxid PF01179.20 KKK14408.1 - 5.5e-162 539.4 0.0 6.6e-162 539.1 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 KKK14408.1 - 8.1e-05 23.0 0.0 0.00018 21.9 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.16 KKK14408.1 - 0.001 19.3 0.1 0.0021 18.3 0.1 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain MFS_1 PF07690.16 KKK14409.1 - 1.2e-37 129.7 50.1 4.9e-37 127.7 50.1 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KKK14409.1 - 0.00018 20.1 23.6 0.00036 19.1 23.6 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF2937 PF11157.8 KKK14409.1 - 0.63 9.7 2.9 0.56 9.9 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) OATP PF03137.20 KKK14409.1 - 2.4 6.3 14.9 80 1.3 14.9 2.5 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Glyco_hydro_43 PF04616.14 KKK14410.1 - 2.2e-37 129.0 4.6 2.6e-37 128.7 4.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 C1q PF00386.21 KKK14410.1 - 0.021 15.0 0.9 4.7 7.4 0.1 2.5 2 0 0 2 2 2 0 C1q domain TNF PF00229.18 KKK14410.1 - 0.2 11.6 1.2 19 5.2 0.1 2.4 2 0 0 2 2 2 0 TNF(Tumour Necrosis Factor) family Fungal_trans PF04082.18 KKK14411.1 - 9.7e-15 54.3 1.1 2.5e-14 52.9 0.0 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK14411.1 - 3.5e-08 33.4 10.2 6.4e-08 32.6 10.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SlyX PF04102.12 KKK14411.1 - 0.094 13.3 1.4 0.35 11.5 0.0 2.5 2 0 0 2 2 2 0 SlyX HSP20 PF00011.21 KKK14412.1 - 1.1e-18 67.3 0.7 5.4e-16 58.6 0.7 2.3 1 1 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KKK14412.1 - 2.5e-06 27.0 0.1 1.4e-05 24.5 0.1 2.0 1 1 0 1 1 1 1 HSP20-like domain found in ArsA ECH_1 PF00378.20 KKK14413.1 - 1.1e-38 133.1 0.3 8.8e-27 94.0 0.1 2.2 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KKK14413.1 - 8.1e-24 84.7 0.0 3.3e-22 79.4 0.0 2.3 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Tfb5 PF06331.12 KKK14414.1 - 5.4e-24 84.0 0.2 6e-24 83.8 0.2 1.0 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 DJ-1_PfpI PF01965.24 KKK14415.1 - 5.9e-07 29.4 0.0 1.5e-05 24.8 0.0 2.1 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 KKK14415.1 - 0.018 14.8 0.1 0.078 12.7 0.0 2.0 2 0 0 2 2 2 0 ThiJ/PfpI family-like IlvN PF07991.12 KKK14416.1 - 5.7e-46 156.1 0.0 8.6e-46 155.5 0.0 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain IlvC PF01450.19 KKK14416.1 - 3.8e-40 137.5 0.0 7.4e-40 136.6 0.0 1.5 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_2 PF03446.15 KKK14416.1 - 0.031 14.4 0.0 0.055 13.6 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 KKK14416.1 - 0.1 13.2 0.0 0.26 11.9 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 2OG-FeII_Oxy_2 PF13532.6 KKK14417.1 - 9.2e-23 81.4 0.0 1.6e-22 80.7 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Isochorismatase PF00857.20 KKK14417.1 - 5.1e-21 75.6 0.0 9e-20 71.6 0.0 2.8 1 1 1 2 2 2 1 Isochorismatase family GST_C_2 PF13410.6 KKK14417.1 - 8.4e-05 22.5 0.0 0.00017 21.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KKK14417.1 - 0.00026 21.1 0.0 0.00048 20.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KKK14417.1 - 0.067 13.4 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Glutaredoxin2_C PF04399.13 KKK14417.1 - 0.13 12.1 0.0 0.29 10.9 0.0 1.5 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain TAF8_C PF10406.9 KKK14418.1 - 1.5e-22 79.9 1.0 3.3e-22 78.8 1.0 1.7 1 0 0 1 1 1 1 Transcription factor TFIID complex subunit 8 C-term Bromo_TP PF07524.13 KKK14418.1 - 2.3e-09 37.2 0.0 1.2e-08 34.8 0.0 1.9 2 0 0 2 2 2 1 Bromodomain associated Mitochondr_Som1 PF11093.8 KKK14419.1 - 3.8e-24 84.5 0.0 4.9e-24 84.1 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial export protein Som1 Rad51 PF08423.11 KKK14420.1 - 6.6e-07 28.8 0.0 0.00021 20.6 0.0 2.2 2 0 0 2 2 2 2 Rad51 PSY3 PF16836.5 KKK14420.1 - 0.16 11.5 0.0 0.29 10.6 0.0 1.5 1 0 0 1 1 1 0 Shu complex component Psy3, DNA-binding description PALP PF00291.25 KKK14421.1 - 4.4e-70 236.4 0.5 5.8e-70 236.0 0.5 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Aminotran_1_2 PF00155.21 KKK14421.1 - 0.011 15.0 0.0 0.21 10.7 0.0 2.2 2 0 0 2 2 2 0 Aminotransferase class I and II UEV PF05743.13 KKK14422.1 - 1.3e-38 131.6 0.1 2e-38 131.0 0.1 1.3 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.10 KKK14422.1 - 9.2e-22 76.8 0.0 1.8e-21 75.8 0.0 1.5 1 0 0 1 1 1 1 Vps23 core domain UQ_con PF00179.26 KKK14422.1 - 0.0038 16.9 0.1 0.0084 15.8 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme KASH_CCD PF14662.6 KKK14422.1 - 0.014 15.3 0.9 0.023 14.5 0.9 1.2 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH KLRAQ PF10205.9 KKK14422.1 - 0.034 14.4 0.3 0.075 13.3 0.3 1.5 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein TMF_TATA_bd PF12325.8 KKK14422.1 - 0.27 11.5 2.0 0.47 10.7 2.0 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Chitin_synth_1 PF01644.17 KKK14423.1 - 5.3e-70 234.6 0.0 1.8e-69 232.9 0.0 1.8 2 0 0 2 2 2 1 Chitin synthase UQ_con PF00179.26 KKK14423.1 - 3.7e-37 127.1 0.0 6.5e-37 126.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Chitin_synth_1N PF08407.11 KKK14423.1 - 5.1e-28 96.8 0.0 9.7e-28 95.9 0.0 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 KKK14423.1 - 1.8e-23 83.0 0.0 1.8e-20 73.1 0.0 2.1 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 KKK14423.1 - 5.1e-10 39.6 0.1 5.1e-10 39.6 0.1 2.5 3 1 0 3 3 3 1 Glycosyl transferase family group 2 PsbX PF06596.11 KKK14423.1 - 1.9 8.5 4.3 6.6 6.8 4.3 1.9 1 0 0 1 1 1 0 Photosystem II reaction centre X protein (PsbX) COX6C PF02937.15 KKK14424.1 - 0.025 14.7 0.0 0.028 14.6 0.0 1.0 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIc Opy2 PF09463.10 KKK14425.1 - 1.3e-10 41.4 23.5 2e-10 40.8 23.5 1.3 1 0 0 1 1 1 1 Opy2 protein Syndecan PF01034.20 KKK14425.1 - 0.1 12.5 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Syndecan domain SKG6 PF08693.10 KKK14425.1 - 0.19 11.2 2.6 0.45 10.0 2.6 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF2981 PF11200.8 KKK14425.1 - 5.1 6.8 6.9 8.1 6.1 6.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) Beta-APP PF03494.13 KKK14425.1 - 5.4 6.9 7.4 9.2 6.2 7.4 1.3 1 0 0 1 1 1 0 Beta-amyloid peptide (beta-APP) FAD_binding_4 PF01565.23 KKK14497.1 - 8.7e-21 74.1 0.4 2e-20 73.0 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 KKK14497.1 - 3.7e-09 36.6 0.0 7.5e-09 35.6 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like N_BRCA1_IG PF16158.5 KKK14500.1 - 1.9e-32 112.0 0.0 4.5e-32 110.8 0.0 1.7 1 0 0 1 1 1 1 Ig-like domain from next to BRCA1 gene ZZ PF00569.17 KKK14500.1 - 5e-21 74.2 51.9 3.7e-07 29.9 9.0 4.4 4 0 0 4 4 4 4 Zinc finger, ZZ type C1_2 PF03107.16 KKK14500.1 - 0.0038 17.5 43.4 0.18 12.1 9.7 4.5 4 0 0 4 4 4 4 C1 domain Drf_GBD PF06371.13 KKK14516.1 - 1.8e-16 60.3 2.0 6.4e-15 55.2 2.0 2.5 1 1 0 1 1 1 1 Diaphanous GTPase-binding Domain Nramp PF01566.18 KKK14518.1 - 3.6e-94 315.7 20.6 7.9e-94 314.6 20.6 1.6 1 1 0 1 1 1 1 Natural resistance-associated macrophage protein Snf7 PF03357.21 KKK14519.1 - 1e-44 152.2 15.4 1.3e-44 151.9 15.4 1.0 1 0 0 1 1 1 1 Snf7 CLZ PF16526.5 KKK14519.1 - 0.0003 21.1 2.3 0.32 11.4 0.0 3.5 2 1 1 3 3 3 2 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Zwint PF15556.6 KKK14519.1 - 0.0018 17.8 3.2 0.0021 17.6 3.2 1.3 1 0 0 1 1 1 1 ZW10 interactor NPV_P10 PF05531.12 KKK14519.1 - 0.019 15.4 5.6 0.17 12.3 0.6 2.7 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Prefoldin_2 PF01920.20 KKK14519.1 - 0.021 14.8 7.8 0.22 11.5 0.0 3.4 2 1 1 3 3 3 0 Prefoldin subunit DUF4201 PF13870.6 KKK14519.1 - 0.024 14.3 8.7 0.022 14.5 6.2 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) HHH_2 PF12826.7 KKK14519.1 - 0.035 14.2 0.0 0.072 13.2 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix motif DUF848 PF05852.11 KKK14519.1 - 0.04 14.0 4.2 0.045 13.9 2.9 1.7 2 1 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) FlaC_arch PF05377.11 KKK14519.1 - 0.14 12.6 6.1 7.7 7.0 0.0 3.3 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) DUF4208 PF13907.6 KKK14519.1 - 0.31 11.5 3.2 0.22 12.0 0.6 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4208) FapA PF03961.13 KKK14519.1 - 2 6.9 8.5 3.3 6.2 2.5 1.9 1 1 1 2 2 2 0 Flagellar Assembly Protein A XhlA PF10779.9 KKK14519.1 - 6.2 7.1 6.6 54 4.1 0.0 3.5 2 1 2 4 4 4 0 Haemolysin XhlA V-ATPase_C PF03223.15 KKK14520.1 - 9.1e-90 301.7 0.0 1.1e-89 301.4 0.0 1.0 1 0 0 1 1 1 1 V-ATPase subunit C GHL13 PF14883.6 KKK14520.1 - 0.03 13.4 0.1 0.041 12.9 0.1 1.1 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase family 13 Phospho_p8 PF10195.9 KKK14520.1 - 0.58 10.7 3.3 7.2 7.2 0.7 2.8 2 0 0 2 2 2 0 DNA-binding nuclear phosphoprotein p8 APS_kinase PF01583.20 KKK14521.1 - 1.3e-70 236.3 0.0 1.6e-70 236.0 0.0 1.1 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.6 KKK14521.1 - 3.5e-06 27.2 0.0 7.8e-06 26.1 0.0 1.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KKK14521.1 - 0.00011 22.8 0.0 0.00016 22.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KKK14521.1 - 0.00061 20.2 0.0 0.00083 19.8 0.0 1.2 1 1 0 1 1 1 1 AAA ATPase domain KTI12 PF08433.10 KKK14521.1 - 0.0048 16.4 0.0 0.0078 15.7 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 G-alpha PF00503.20 KKK14521.1 - 0.037 13.2 0.0 0.063 12.4 0.0 1.5 2 0 0 2 2 2 0 G-protein alpha subunit Zeta_toxin PF06414.12 KKK14521.1 - 0.047 13.0 0.0 0.068 12.4 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_29 PF13555.6 KKK14521.1 - 0.11 12.3 0.1 0.18 11.5 0.1 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain BRO1 PF03097.18 KKK14530.1 - 6.3e-126 420.3 0.1 1.2e-125 419.3 0.1 1.5 1 0 0 1 1 1 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 KKK14530.1 - 4.5e-64 216.6 11.1 5e-61 206.6 11.1 2.4 1 1 0 1 1 1 1 ALIX V-shaped domain binding to HIV DnaJ_C PF01556.18 KKK14530.1 - 1.3e-33 116.1 0.0 2.2e-33 115.4 0.0 1.4 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KKK14530.1 - 3e-22 78.5 0.6 8.2e-22 77.1 0.6 1.8 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KKK14530.1 - 2.6e-09 37.3 20.2 5.5e-09 36.3 20.2 1.6 1 0 0 1 1 1 1 DnaJ central domain Cytochrome_C7 PF14522.6 KKK14530.1 - 0.41 10.7 4.1 7.7 6.6 0.3 2.8 2 0 0 2 2 2 0 Cytochrome c7 and related cytochrome c Anti-TRAP PF15777.5 KKK14530.1 - 4.2 7.4 16.7 0.14 12.1 2.9 3.2 2 1 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein Lon_C PF05362.13 KKK14531.1 - 9.2e-52 175.6 0.0 1.5e-51 174.8 0.0 1.4 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 KKK14531.1 - 2.6e-33 115.7 0.0 6.6e-33 114.3 0.0 1.7 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 KKK14531.1 - 8.5e-22 78.0 0.0 2e-21 76.8 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KKK14531.1 - 2.4e-07 30.8 0.0 4.6e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KKK14531.1 - 2.9e-06 27.5 0.0 8.7e-06 26.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 KKK14531.1 - 7.8e-06 26.2 0.1 9.6e-05 22.7 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_PrkA PF08298.11 KKK14531.1 - 3.5e-05 22.9 0.2 8e-05 21.7 0.0 1.6 2 0 0 2 2 2 1 PrkA AAA domain ChlI PF13541.6 KKK14531.1 - 5.2e-05 23.1 0.1 0.00026 20.8 0.1 2.2 1 1 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_16 PF13191.6 KKK14531.1 - 0.00012 22.5 1.1 0.00063 20.2 0.0 2.5 2 1 1 3 3 2 1 AAA ATPase domain RuvB_N PF05496.12 KKK14531.1 - 0.00021 21.1 0.0 0.00068 19.4 0.0 1.8 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 KKK14531.1 - 0.0013 19.3 0.9 0.0038 17.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 KKK14531.1 - 0.0047 17.0 0.0 0.012 15.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KKK14531.1 - 0.016 15.0 0.0 0.037 13.8 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_30 PF13604.6 KKK14531.1 - 0.022 14.5 0.0 0.052 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 KKK14531.1 - 0.023 14.6 0.1 0.35 10.8 0.0 2.7 2 1 1 3 3 3 0 NTPase DUF4276 PF14103.6 KKK14531.1 - 0.025 14.8 0.7 0.063 13.5 0.2 1.8 2 0 0 2 2 1 0 Domain of unknown function (DUF4276) RNA_helicase PF00910.22 KKK14531.1 - 0.036 14.4 0.0 0.13 12.6 0.0 2.0 1 0 0 1 1 1 0 RNA helicase RsgA_GTPase PF03193.16 KKK14531.1 - 0.054 13.4 0.0 0.16 11.8 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase MCM PF00493.23 KKK14531.1 - 0.093 11.8 0.0 0.19 10.8 0.0 1.5 1 0 0 1 1 1 0 MCM P-loop domain DNTTIP1_dimer PF18192.1 KKK14531.1 - 0.096 13.0 1.1 11 6.5 0.1 3.3 2 2 0 2 2 2 0 DNTTIP1 dimerisation domain AAA_7 PF12775.7 KKK14531.1 - 0.1 12.1 0.0 0.23 10.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region ABC_tran PF00005.27 KKK14531.1 - 0.15 12.6 1.6 0.33 11.5 0.1 2.3 2 0 0 2 2 2 0 ABC transporter TsaE PF02367.17 KKK14531.1 - 0.15 12.1 0.0 0.33 10.9 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 KKK14531.1 - 0.18 11.7 0.0 0.66 9.9 0.0 2.0 1 1 0 1 1 1 0 NACHT domain Pkinase PF00069.25 KKK14532.1 - 3.1e-10 39.9 0.0 4e-09 36.2 0.0 2.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK14532.1 - 2.6e-09 36.8 0.0 2.7e-08 33.4 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase cobW PF02492.19 KKK14533.1 - 1.3e-20 73.7 0.0 1.8e-20 73.2 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 KKK14533.1 - 2e-05 24.4 0.0 3.5e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain DUF2577 PF10844.8 KKK14533.1 - 0.089 13.0 0.0 0.16 12.2 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2577) SAP30_Sin3_bdg PF13867.6 KKK14534.1 - 1.1e-08 35.2 0.1 1.2e-07 31.9 0.0 2.4 2 0 0 2 2 2 1 Sin3 binding region of histone deacetylase complex subunit SAP30 DUF410 PF04190.13 KKK14534.1 - 0.091 12.6 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF410) CNDH2_M PF16869.5 KKK14534.1 - 9 7.0 9.4 0.61 10.8 2.0 2.2 2 1 0 2 2 2 0 PF16858 Pyr_redox_2 PF07992.14 KKK14538.1 - 1.2e-50 172.4 0.2 1.4e-50 172.2 0.2 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KKK14538.1 - 6.5e-14 52.3 0.5 1.4e-13 51.2 0.5 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KKK14538.1 - 4.1e-13 49.3 0.4 1.1e-11 44.6 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KKK14538.1 - 4.3e-05 22.8 0.0 5.8e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) 3HCDH_N PF02737.18 KKK14538.1 - 0.00015 21.7 0.5 0.00028 20.8 0.5 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pkinase PF00069.25 KKK14539.1 - 1.2e-54 185.5 0.0 9.1e-52 176.0 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KKK14539.1 - 3.6e-31 108.4 0.0 2e-30 105.9 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Seadorna_VP7 PF07387.11 KKK14539.1 - 0.0043 16.1 0.1 0.0083 15.2 0.1 1.4 1 0 0 1 1 1 1 Seadornavirus VP7 Kinase-like PF14531.6 KKK14539.1 - 0.011 15.1 0.0 0.017 14.5 0.0 1.1 1 0 0 1 1 1 0 Kinase-like Pkinase_fungal PF17667.1 KKK14539.1 - 0.017 13.9 0.0 0.026 13.3 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 KKK14539.1 - 0.11 11.4 0.0 0.16 10.9 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Peptidase_C12 PF01088.21 KKK14540.1 - 7.5e-49 166.3 0.0 1.1e-48 165.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 KKK14540.1 - 2.5e-09 36.9 0.0 6.4e-09 35.6 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolases Kei1 PF08552.11 KKK14540.1 - 0.099 12.5 0.8 0.16 11.8 0.8 1.3 1 1 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 DUF5421 PF17458.2 KKK14540.1 - 0.14 11.5 0.7 0.28 10.5 0.7 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5421) Zn_clus PF00172.18 KKK14541.1 - 6.9e-08 32.5 13.2 6.9e-08 32.5 13.2 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KKK14541.1 - 2.3e-06 26.7 1.8 3.4e-06 26.1 1.8 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain TPR_15 PF13429.6 KKK14541.1 - 0.12 11.6 0.3 0.28 10.4 0.0 1.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Mem_trans PF03547.18 KKK14542.1 - 7e-56 189.3 0.1 9.6e-56 188.8 0.1 1.2 1 0 0 1 1 1 1 Membrane transport protein Choline_kinase PF01633.20 KKK14543.1 - 7.5e-60 202.1 0.0 2.3e-59 200.5 0.0 1.8 2 0 0 2 2 2 1 Choline/ethanolamine kinase Choline_kin_N PF04428.14 KKK14543.1 - 1.1e-16 60.2 0.0 2.8e-16 58.9 0.0 1.7 1 0 0 1 1 1 1 Choline kinase N terminus APH PF01636.23 KKK14543.1 - 1.2e-05 25.3 0.4 3.3e-05 23.9 0.4 1.8 1 0 0 1 1 1 1 Phosphotransferase enzyme family ATP11 PF06644.11 KKK14573.1 - 2.4e-99 332.6 0.0 2.7e-99 332.4 0.0 1.0 1 0 0 1 1 1 1 ATP11 protein CAP_N PF01213.19 KKK14573.1 - 0.059 12.8 8.5 0.09 12.2 8.5 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Myb_DNA-bind_6 PF13921.6 KKK14573.1 - 0.078 13.2 0.1 0.15 12.3 0.1 1.4 1 0 0 1 1 1 0 Myb-like DNA-binding domain Evr1_Alr PF04777.13 KKK14574.1 - 1.5e-25 89.6 0.8 3.7e-25 88.3 0.0 2.1 2 0 0 2 2 2 1 Erv1 / Alr family zf-LYAR PF08790.11 KKK14574.1 - 2.2e-14 53.0 3.3 6.3e-14 51.6 3.3 1.9 1 0 0 1 1 1 1 LYAR-type C2HC zinc finger APOBEC4 PF18775.1 KKK14574.1 - 0.13 12.4 0.1 0.28 11.4 0.1 1.5 1 0 0 1 1 1 0 APOBEC4 Zf_RING PF16744.5 KKK14575.1 - 1.4e-05 25.1 0.3 3.1e-05 24.0 0.3 1.5 1 0 0 1 1 1 1 KIAA1045 RING finger Zn_ribbon_17 PF17120.5 KKK14575.1 - 5.4e-05 22.7 2.4 8.9e-05 22.0 2.4 1.3 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_2 PF13639.6 KKK14575.1 - 0.00062 20.0 3.4 0.00098 19.4 3.4 1.3 1 0 0 1 1 1 1 Ring finger domain C1_1 PF00130.22 KKK14575.1 - 0.0028 17.5 1.1 0.0047 16.8 1.1 1.3 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_4 PF16866.5 KKK14575.1 - 0.0034 17.4 0.6 0.27 11.4 0.0 2.3 1 1 1 2 2 2 1 PHD-finger Prok-RING_1 PF14446.6 KKK14575.1 - 0.0034 17.3 0.6 0.0064 16.4 0.6 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 FYVE PF01363.21 KKK14575.1 - 0.01 15.9 0.3 0.019 15.1 0.3 1.3 1 0 0 1 1 1 0 FYVE zinc finger C1_2 PF03107.16 KKK14575.1 - 0.095 13.0 1.0 0.16 12.3 1.0 1.3 1 0 0 1 1 1 0 C1 domain PHD PF00628.29 KKK14575.1 - 0.099 12.5 1.2 0.18 11.7 1.2 1.4 1 0 0 1 1 1 0 PHD-finger zf-C3HC4_2 PF13923.6 KKK14575.1 - 0.2 11.6 1.2 0.35 10.7 1.2 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KKK14575.1 - 0.87 9.4 2.5 1.6 8.5 2.5 1.5 1 0 0 1 1 1 0 RING-like zinc finger zf-rbx1 PF12678.7 KKK14575.1 - 4.8 7.6 6.2 12 6.3 6.2 1.6 1 1 0 1 1 1 0 RING-H2 zinc finger domain R3H PF01424.22 KKK14576.1 - 6e-12 45.4 0.1 1.1e-11 44.5 0.1 1.5 1 0 0 1 1 1 1 R3H domain SDA1 PF05285.12 KKK14576.1 - 1.3e-05 24.9 2.4 1.9e-05 24.3 2.4 1.1 1 0 0 1 1 1 1 SDA1 SAPS PF04499.15 KKK14576.1 - 0.21 10.3 2.9 0.27 10.0 2.9 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SelP_N PF04592.14 KKK14576.1 - 0.65 9.4 17.6 1.1 8.7 17.6 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Trypan_PARP PF05887.11 KKK14576.1 - 0.66 9.9 11.4 1.6 8.7 11.4 1.7 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) CCSAP PF15748.5 KKK14576.1 - 5 7.2 15.1 2.1 8.4 7.2 2.7 2 1 0 2 2 2 0 Centriole, cilia and spindle-associated MFS_1 PF07690.16 KKK14577.1 - 2.3e-17 63.0 56.3 1.6e-16 60.2 51.1 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF2976 PF11190.8 KKK14577.1 - 0.0011 18.7 0.3 0.0011 18.7 0.3 4.3 5 0 0 5 5 5 1 Protein of unknown function (DUF2976) Fungal_trans_2 PF11951.8 KKK14578.1 - 1.3e-07 30.8 0.0 1.9e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain SF-assemblin PF06705.11 KKK14578.1 - 0.013 14.9 0.0 0.018 14.4 0.0 1.1 1 0 0 1 1 1 0 SF-assemblin/beta giardin AATase PF07247.12 KKK14579.1 - 0.0012 17.5 0.0 0.0027 16.3 0.0 1.5 1 1 0 1 1 1 1 Alcohol acetyltransferase Tri3 PF07428.11 KKK14579.1 - 0.016 14.2 0.0 0.083 11.8 0.0 1.9 2 0 0 2 2 2 0 15-O-acetyltransferase Tri3 DUF1688 PF07958.11 KKK14583.1 - 2.5e-161 537.1 0.0 2.8e-161 536.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) UPRTase PF14681.6 KKK14584.1 - 2.4e-66 223.1 0.0 3e-66 222.8 0.0 1.1 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 KKK14584.1 - 0.00084 18.9 0.1 0.0011 18.5 0.1 1.4 1 1 0 1 1 1 1 Phosphoribosyl transferase domain MreB_Mbl PF06723.13 KKK14585.1 - 0.066 12.0 0.0 0.14 11.0 0.0 1.4 2 0 0 2 2 2 0 MreB/Mbl protein HSP70 PF00012.20 KKK14585.1 - 0.1 10.7 0.0 0.18 10.0 0.0 1.4 1 1 0 1 1 1 0 Hsp70 protein IMPDH PF00478.25 KKK14585.1 - 0.25 10.3 0.2 1.2 8.0 0.0 1.9 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain Fungal_trans PF04082.18 KKK14586.1 - 3e-08 33.0 0.0 3.1e-07 29.7 0.0 2.5 3 0 0 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK14586.1 - 5.9e-07 29.5 8.4 1.2e-06 28.5 8.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain LCIB_C_CA PF18599.1 KKK14586.1 - 0.25 10.6 0.4 0.39 10.0 0.4 1.2 1 0 0 1 1 1 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases MFS_1 PF07690.16 KKK14587.1 - 2e-29 102.7 39.0 2e-29 102.7 39.0 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily DPM2 PF07297.12 KKK14587.1 - 0.017 15.4 0.1 0.12 12.7 0.1 2.6 1 0 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) MFS_4 PF06779.14 KKK14587.1 - 0.28 10.4 20.3 0.065 12.5 6.2 2.4 2 1 0 2 2 2 0 Uncharacterised MFS-type transporter YbfB ZZ PF00569.17 KKK14591.1 - 6.1e-11 42.0 6.2 9.9e-11 41.3 6.2 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type SWIRM PF04433.17 KKK14591.1 - 2.3e-10 40.7 0.0 7.1e-10 39.1 0.0 1.8 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-binding PF00249.31 KKK14591.1 - 2.7e-10 40.3 0.0 8.3e-10 38.7 0.0 1.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain Pkinase PF00069.25 KKK14592.1 - 6.7e-71 238.7 0.0 9.2e-71 238.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK14592.1 - 6.3e-33 114.2 0.0 8.8e-33 113.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 KKK14592.1 - 1e-10 42.2 1.0 3.3e-10 40.5 1.0 2.0 1 0 0 1 1 1 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 KKK14592.1 - 8.1e-07 28.3 0.0 1.3e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KKK14592.1 - 0.035 13.4 0.0 0.063 12.6 0.0 1.4 1 0 0 1 1 1 0 Kinase-like ECH_1 PF00378.20 KKK14593.1 - 7.8e-57 192.4 0.0 9.9e-57 192.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KKK14593.1 - 6.1e-25 88.4 0.1 1.1e-23 84.3 0.0 2.1 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Mannitol_dh_C PF08125.13 KKK14595.1 - 1.3e-41 142.8 0.0 2.2e-41 142.0 0.0 1.3 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.23 KKK14595.1 - 1.3e-12 48.2 1.2 5.3e-12 46.1 0.0 2.3 3 0 0 3 3 3 1 Mannitol dehydrogenase Rossmann domain Mit_ribos_Mrp51 PF11709.8 KKK14596.1 - 1.3e-112 377.0 0.1 1.7e-112 376.6 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit Epimerase PF01370.21 KKK14596.1 - 4e-16 59.2 0.0 6.8e-16 58.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KKK14596.1 - 1.4e-09 37.4 0.0 2.2e-09 36.7 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KKK14596.1 - 4.5e-09 36.2 0.0 7.3e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 KKK14596.1 - 1.9e-06 27.2 0.0 7.8e-06 25.2 0.0 1.9 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 KKK14596.1 - 0.00012 22.1 0.0 0.00022 21.2 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 KKK14596.1 - 0.0041 16.6 0.0 0.007 15.8 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KKK14596.1 - 0.036 14.0 0.0 0.068 13.1 0.0 1.4 1 0 0 1 1 1 0 KR domain UPF0184 PF03670.13 KKK14596.1 - 0.041 14.3 0.6 0.098 13.1 0.6 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0184) Ribosomal_S17e PF00833.18 KKK14597.1 - 2.8e-60 201.6 1.0 3.4e-60 201.3 1.0 1.1 1 0 0 1 1 1 1 Ribosomal S17 RPAP2_Rtr1 PF04181.13 KKK14598.1 - 3.7e-22 78.4 0.0 6.3e-22 77.7 0.0 1.4 1 0 0 1 1 1 1 Rtr1/RPAP2 family CaM_binding PF07839.11 KKK14598.1 - 0.15 12.8 0.0 0.28 11.9 0.0 1.4 1 0 0 1 1 1 0 Plant calmodulin-binding domain GATA PF00320.27 KKK14609.1 - 3.7e-16 58.4 5.2 7.3e-16 57.5 5.2 1.5 1 0 0 1 1 1 1 GATA zinc finger PAS_3 PF08447.12 KKK14609.1 - 1.4e-05 25.3 0.0 0.00015 22.0 0.0 2.2 2 0 0 2 2 2 1 PAS fold PAS PF00989.25 KKK14609.1 - 4.6e-05 23.4 0.0 0.00046 20.2 0.0 2.4 2 0 0 2 2 2 1 PAS fold PAS_4 PF08448.10 KKK14609.1 - 0.0042 17.3 0.0 0.019 15.2 0.0 2.1 2 0 0 2 2 2 1 PAS fold Zn-ribbon_8 PF09723.10 KKK14609.1 - 0.0055 16.8 0.4 0.013 15.6 0.4 1.6 1 0 0 1 1 1 1 Zinc ribbon domain PAS_9 PF13426.7 KKK14609.1 - 0.011 16.0 0.0 0.09 13.0 0.0 2.3 2 0 0 2 2 2 0 PAS domain GRAB PF10375.9 KKK14611.1 - 1.4e-08 34.3 0.1 2.7e-08 33.4 0.1 1.5 1 0 0 1 1 1 1 GRIP-related Arf-binding domain Phage_GP20 PF06810.11 KKK14611.1 - 0.00026 20.8 36.1 0.0005 19.9 2.9 4.8 2 1 2 5 5 5 3 Phage minor structural protein GP20 Filament PF00038.21 KKK14611.1 - 0.00027 20.7 44.5 0.0052 16.4 16.4 3.3 1 1 2 3 3 3 3 Intermediate filament protein RPW8 PF05659.11 KKK14611.1 - 0.002 17.8 1.3 0.002 17.8 1.3 3.6 2 1 2 4 4 4 1 Arabidopsis broad-spectrum mildew resistance protein RPW8 Tup_N PF08581.10 KKK14611.1 - 0.0036 17.6 3.1 0.0036 17.6 3.1 4.8 3 2 1 4 4 4 2 Tup N-terminal Golgin_A5 PF09787.9 KKK14611.1 - 0.0052 16.3 49.1 0.32 10.4 21.1 3.4 1 1 2 3 3 3 2 Golgin subfamily A member 5 Spc7 PF08317.11 KKK14611.1 - 0.015 14.2 46.2 0.48 9.2 14.9 2.6 1 1 1 2 2 2 0 Spc7 kinetochore protein Fib_alpha PF08702.10 KKK14611.1 - 0.022 15.0 1.0 0.022 15.0 1.0 3.8 2 1 2 4 4 4 0 Fibrinogen alpha/beta chain family XhlA PF10779.9 KKK14611.1 - 0.022 14.9 22.9 0.096 12.9 1.6 4.7 3 1 1 4 4 4 0 Haemolysin XhlA DUF4407 PF14362.6 KKK14611.1 - 0.038 13.3 38.9 0.2 11.0 13.6 3.2 1 1 2 3 3 3 0 Domain of unknown function (DUF4407) DUF3584 PF12128.8 KKK14611.1 - 0.24 8.9 45.1 0.17 9.4 7.7 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) IFT57 PF10498.9 KKK14611.1 - 0.35 9.8 40.6 0.72 8.8 1.6 3.3 1 1 2 3 3 3 0 Intra-flagellar transport protein 57 NPV_P10 PF05531.12 KKK14611.1 - 0.73 10.3 14.1 1.5 9.3 0.2 4.5 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein BST2 PF16716.5 KKK14611.1 - 2 9.0 40.3 11 6.7 0.5 5.9 1 1 2 5 5 5 0 Bone marrow stromal antigen 2 HOOK PF05622.12 KKK14611.1 - 3.6 5.6 51.2 1.3 7.1 22.1 3.9 1 1 2 3 3 3 0 HOOK protein ATG16 PF08614.11 KKK14611.1 - 4.3 7.5 56.5 2.7 8.2 13.2 3.8 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) DUF2937 PF11157.8 KKK14611.1 - 4.3 7.0 11.9 0.67 9.7 2.7 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF2937) Atg14 PF10186.9 KKK14611.1 - 4.8 6.2 37.9 0.22 10.6 22.8 2.5 1 1 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 TPR_MLP1_2 PF07926.12 KKK14611.1 - 5.6 7.0 57.7 0.25 11.4 11.8 4.7 2 1 3 5 5 5 0 TPR/MLP1/MLP2-like protein DUF745 PF05335.13 KKK14611.1 - 7.9 6.2 36.7 4.8 6.9 6.3 4.1 1 1 2 3 3 3 0 Protein of unknown function (DUF745) MAD PF05557.13 KKK14611.1 - 9.1 4.5 49.3 3 6.1 23.0 2.1 1 1 1 2 2 2 0 Mitotic checkpoint protein ATP-synt_ab PF00006.25 KKK14618.1 - 3.4e-68 229.5 0.0 5.6e-68 228.8 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 KKK14618.1 - 3.8e-10 40.2 0.2 1e-09 38.8 0.2 1.8 1 1 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain Usp PF00582.26 KKK14619.1 - 2.1e-18 67.2 3.8 2.8e-17 63.6 0.8 3.0 2 1 0 2 2 2 1 Universal stress protein family Rotamase_3 PF13616.6 KKK14637.1 - 7.2e-15 55.6 0.0 1.5e-14 54.6 0.0 1.6 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.21 KKK14637.1 - 4.6e-13 49.9 0.0 7e-13 49.4 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 KKK14637.1 - 7.7e-05 23.5 0.0 0.00012 22.9 0.0 1.3 1 1 0 1 1 1 1 PPIC-type PPIASE domain UAA PF08449.11 KKK14638.1 - 1.6e-41 142.5 13.2 4.3e-41 141.1 13.2 1.6 1 1 0 1 1 1 1 UAA transporter family Nuc_sug_transp PF04142.15 KKK14638.1 - 3e-06 26.6 1.9 0.018 14.3 0.1 2.3 2 0 0 2 2 2 2 Nucleotide-sugar transporter EamA PF00892.20 KKK14638.1 - 1.3e-05 25.3 10.6 1.3e-05 25.3 10.6 3.4 3 1 0 3 3 3 2 EamA-like transporter family Sen15 PF09631.10 KKK14639.1 - 3.2e-16 59.4 0.0 1.5e-14 54.1 0.0 2.1 1 1 0 1 1 1 1 Sen15 protein VASt PF16016.5 KKK14640.1 - 1.8e-32 112.9 0.1 3.8e-32 111.8 0.1 1.6 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain BAR_3 PF16746.5 KKK14640.1 - 1.9e-17 63.8 0.6 3.4e-17 62.9 0.0 1.7 2 0 0 2 2 2 1 BAR domain of APPL family PH PF00169.29 KKK14640.1 - 1.9e-09 37.9 0.0 8.1e-09 35.9 0.0 2.2 2 0 0 2 2 2 1 PH domain GRAM PF02893.20 KKK14640.1 - 0.00028 20.7 0.0 0.00066 19.5 0.0 1.5 1 0 0 1 1 1 1 GRAM domain BAR PF03114.18 KKK14640.1 - 0.0047 16.6 0.6 0.011 15.4 0.6 1.6 1 0 0 1 1 1 1 BAR domain Kri1_C PF12936.7 KKK14641.1 - 2.4e-32 110.9 0.5 2.4e-32 110.9 0.5 3.6 2 1 1 3 3 3 1 KRI1-like family C-terminal Kri1 PF05178.12 KKK14641.1 - 5.1e-30 104.1 16.5 5.1e-30 104.1 16.5 4.6 5 1 1 6 6 6 1 KRI1-like family CRISPR_Cse2 PF09485.10 KKK14641.1 - 0.014 15.9 1.2 0.032 14.7 1.2 1.6 1 0 0 1 1 1 0 CRISPR-associated protein Cse2 (CRISPR_cse2) Mito_carr PF00153.27 KKK14642.1 - 6e-67 221.6 6.1 3.1e-24 84.7 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Aldo_ket_red PF00248.21 KKK14693.1 - 5.1e-43 147.3 0.0 4.2e-39 134.5 0.0 2.3 1 1 1 2 2 2 2 Aldo/keto reductase family zf-H2C2_2 PF13465.6 KKK14694.1 - 2.8e-07 30.6 7.4 2.5e-06 27.7 0.6 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_6 PF13912.6 KKK14694.1 - 7e-07 29.1 1.5 0.011 15.7 0.0 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KKK14694.1 - 7.6e-06 26.1 0.3 7.6e-06 26.1 0.3 3.8 3 1 0 3 3 3 1 Zinc finger, C2H2 type FOXP-CC PF16159.5 KKK14694.1 - 3.1e-05 24.5 5.2 0.19 12.4 0.0 3.1 2 1 1 3 3 3 2 FOXP coiled-coil domain zf-C2H2_4 PF13894.6 KKK14694.1 - 8.9e-05 23.0 7.1 0.0052 17.5 0.2 3.7 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KKK14694.1 - 0.092 13.1 1.4 2.7 8.4 0.2 3.2 3 1 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KKK14694.1 - 0.18 12.2 1.0 10 6.7 0.0 3.2 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 KKK14694.1 - 0.18 11.6 0.5 0.56 10.0 0.0 2.0 2 0 0 2 2 2 0 zinc-finger C2H2-type zf_ZIC PF18366.1 KKK14694.1 - 7.4 6.8 8.5 3 8.0 1.7 3.3 3 1 0 3 3 3 0 Zic proteins zinc finger domain zf-C2H2 PF00096.26 KKK14695.1 - 1.1e-07 31.9 10.4 6.5e-06 26.3 2.8 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KKK14695.1 - 1.8e-05 24.9 2.5 1.8e-05 24.9 2.5 4.0 4 0 0 4 4 4 1 Zinc-finger double domain zf-met PF12874.7 KKK14695.1 - 0.00015 22.0 8.4 0.0006 20.1 0.5 2.6 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 KKK14695.1 - 0.00019 22.0 1.2 0.00019 22.0 1.2 3.2 3 0 0 3 3 3 1 C2H2-type zinc finger DUF2225 PF09986.9 KKK14695.1 - 0.001 18.8 0.1 0.0017 18.1 0.1 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2225) zf-Di19 PF05605.12 KKK14695.1 - 0.0016 18.7 5.8 0.0028 17.9 5.8 1.4 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.8 KKK14695.1 - 0.0077 16.5 0.5 0.0077 16.5 0.5 1.8 2 0 0 2 2 1 1 Zinc-finger double-stranded RNA-binding zf-BED PF02892.15 KKK14695.1 - 0.015 15.3 2.2 0.029 14.4 2.2 1.6 1 0 0 1 1 1 0 BED zinc finger DUF1178 PF06676.11 KKK14695.1 - 0.035 14.5 1.3 0.035 14.5 1.3 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1178) zf-C2H2_6 PF13912.6 KKK14695.1 - 0.036 14.1 2.9 0.059 13.4 0.4 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KKK14695.1 - 0.036 13.8 0.2 0.036 13.8 0.2 3.2 4 0 0 4 4 4 0 C2H2-type zinc-finger domain zf-C2H2_2 PF12756.7 KKK14695.1 - 0.086 13.2 1.9 0.14 12.5 1.9 1.3 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) DUF533 PF04391.12 KKK14696.1 - 0.037 13.6 0.3 1.7 8.2 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF533) Trypan_PARP PF05887.11 KKK14697.1 - 1.9 8.5 9.2 0.19 11.7 2.4 2.2 2 1 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Nop PF01798.18 KKK14698.1 - 4.2e-62 209.6 0.1 5.9e-62 209.1 0.1 1.2 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin Prp31_C PF09785.9 KKK14698.1 - 7e-48 162.5 0.9 2.3e-47 160.8 0.9 2.0 1 1 0 1 1 1 1 Prp31 C terminal domain TPR_14 PF13428.6 KKK14699.1 - 3.2e-21 74.2 21.0 0.00049 20.7 0.0 11.4 7 2 7 14 14 14 6 Tetratricopeptide repeat HAT PF02184.16 KKK14699.1 - 5.8e-21 74.1 76.4 1.7e-13 50.2 6.0 12.7 13 0 0 13 13 13 6 HAT (Half-A-TPR) repeat Suf PF05843.14 KKK14699.1 - 2.3e-17 63.9 22.3 8.8e-06 25.9 0.7 6.3 3 2 4 7 7 7 4 Suppressor of forked protein (Suf) TPR_19 PF14559.6 KKK14699.1 - 1.2e-14 54.6 0.0 0.00019 21.9 0.0 6.6 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_17 PF13431.6 KKK14699.1 - 2.5e-09 36.8 0.4 0.22 12.0 0.0 6.4 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.17 KKK14699.1 - 1e-07 31.5 8.4 0.12 12.5 0.0 7.9 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_8 PF13181.6 KKK14699.1 - 0.00068 19.7 3.9 42 4.7 0.0 7.3 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_6 PF13174.6 KKK14699.1 - 0.013 16.1 16.1 3.6 8.4 0.0 6.9 8 0 0 8 8 6 0 Tetratricopeptide repeat TPR_16 PF13432.6 KKK14699.1 - 0.022 15.4 11.1 3.8 8.2 0.0 7.5 8 1 1 9 9 9 0 Tetratricopeptide repeat NRDE-2 PF08424.10 KKK14699.1 - 0.072 12.2 27.0 0.15 11.1 0.0 6.3 4 3 1 5 5 5 0 NRDE-2, necessary for RNA interference TPR_1 PF00515.28 KKK14699.1 - 0.088 12.7 1.6 6.4 6.8 0.0 4.3 5 0 0 5 5 4 0 Tetratricopeptide repeat QIL1 PF15884.5 KKK14699.1 - 0.12 13.0 0.0 4.8 7.9 0.0 3.5 2 0 0 2 2 2 0 MICOS complex subunit MIC13, QIL1 NifW PF03206.14 KKK14699.1 - 0.16 12.5 1.3 2.1 8.9 0.2 3.3 3 0 0 3 3 3 0 Nitrogen fixation protein NifW U3_assoc_6 PF08640.11 KKK14699.1 - 0.54 10.4 0.1 0.54 10.4 0.1 6.7 7 1 1 8 8 8 0 U3 small nucleolar RNA-associated protein 6 TPR_12 PF13424.6 KKK14699.1 - 4.1 7.8 15.9 15 6.0 0.0 6.9 9 0 0 9 9 8 0 Tetratricopeptide repeat Kelch_3 PF13415.6 KKK14700.1 - 2.6e-05 24.4 4.9 0.026 14.8 0.4 4.6 3 1 0 3 3 3 2 Galactose oxidase, central domain TMEM154 PF15102.6 KKK14700.1 - 9e-05 22.4 0.0 0.00036 20.4 0.0 2.0 1 0 0 1 1 1 1 TMEM154 protein family Kelch_6 PF13964.6 KKK14700.1 - 0.00011 22.4 6.1 3.1 8.2 0.0 4.9 5 0 0 5 5 5 2 Kelch motif Kelch_5 PF13854.6 KKK14700.1 - 0.0005 20.0 2.8 0.78 9.8 0.1 3.4 3 0 0 3 3 3 2 Kelch motif Kelch_1 PF01344.25 KKK14700.1 - 0.026 14.1 0.2 0.53 9.9 0.0 3.2 3 0 0 3 3 3 0 Kelch motif Gram_pos_anchor PF00746.21 KKK14700.1 - 0.04 13.9 2.1 0.13 12.2 2.1 1.9 1 0 0 1 1 1 0 LPXTG cell wall anchor motif Gly-zipper_Omp PF13488.6 KKK14700.1 - 0.071 13.1 0.4 0.071 13.1 0.4 2.1 2 0 0 2 2 2 0 Glycine zipper DUF2407_C PF13373.6 KKK14700.1 - 0.12 12.6 0.0 0.22 11.7 0.0 1.4 1 0 0 1 1 1 0 DUF2407 C-terminal domain Rick_17kDa_Anti PF05433.15 KKK14700.1 - 0.46 10.4 7.5 0.21 11.5 3.8 2.3 2 0 0 2 2 2 0 Glycine zipper 2TM domain Podoplanin PF05808.11 KKK14700.1 - 7.8 6.6 15.6 0.71 10.0 10.5 1.9 2 1 0 2 2 2 0 Podoplanin adh_short PF00106.25 KKK14701.1 - 1.1e-31 109.8 0.0 2.2e-31 108.8 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KKK14701.1 - 2e-31 109.4 0.1 7.1e-31 107.6 0.0 1.9 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KKK14701.1 - 7.3e-08 32.5 0.0 2.2e-07 31.0 0.0 1.8 1 0 0 1 1 1 1 KR domain Androgen_recep PF02166.16 KKK14701.1 - 7.1 5.3 19.4 2.4 6.9 7.5 2.1 2 0 0 2 2 2 0 Androgen receptor AdoHcyase PF05221.17 KKK14702.1 - 2.1e-129 430.9 0.0 3.1e-74 249.8 0.2 2.0 1 1 1 2 2 2 2 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 KKK14702.1 - 2.5e-83 278.0 1.3 3.8e-83 277.4 1.3 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 KKK14702.1 - 9.2e-06 25.1 0.1 1.9e-05 24.1 0.1 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 KKK14702.1 - 0.00037 20.1 0.2 0.00068 19.2 0.2 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain TrkA_N PF02254.18 KKK14702.1 - 0.0018 18.5 0.1 0.0038 17.5 0.1 1.5 1 0 0 1 1 1 1 TrkA-N domain Oxidored_nitro PF00148.19 KKK14702.1 - 0.032 13.0 0.1 0.35 9.6 0.0 2.1 2 0 0 2 2 2 0 Nitrogenase component 1 type Oxidoreductase ELFV_dehydrog PF00208.21 KKK14702.1 - 0.054 13.2 0.1 0.1 12.3 0.1 1.5 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase DUF1349 PF07081.11 KKK14710.1 - 1.7e-21 76.8 0.0 2.1e-21 76.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1349) Peptidase_M24 PF00557.24 KKK14759.1 - 2e-29 102.8 0.0 9.9e-28 97.3 0.0 2.1 1 1 0 1 1 1 1 Metallopeptidase family M24 Glyco_transf_54 PF04666.13 KKK14760.1 - 4.5e-11 42.2 0.2 6.6e-05 21.9 0.0 3.1 3 0 0 3 3 3 3 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region Pam17 PF08566.10 KKK14761.1 - 1.5e-67 226.5 0.1 1.5e-67 226.5 0.1 1.9 3 0 0 3 3 3 1 Mitochondrial import protein Pam17 Far-17a_AIG1 PF04750.14 KKK14761.1 - 2.6e-61 206.5 8.3 4.7e-61 205.6 8.3 1.4 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein Fungal_trans_2 PF11951.8 KKK14762.1 - 5.1e-08 32.1 0.4 5.1e-08 32.1 0.4 2.2 2 1 1 3 3 3 1 Fungal specific transcription factor domain HECT PF00632.25 KKK14762.1 - 0.17 11.4 0.0 0.39 10.2 0.0 1.6 1 0 0 1 1 1 0 HECT-domain (ubiquitin-transferase) DUF3602 PF12223.8 KKK14763.1 - 1.1e-13 51.6 2.1 1.1e-13 51.6 2.1 2.9 2 2 1 3 3 3 2 Protein of unknown function (DUF3602) SUN PF03856.13 KKK14766.1 - 2.4e-80 269.6 11.2 2.4e-80 269.6 11.2 1.7 2 0 0 2 2 2 1 Beta-glucosidase (SUN family) zinc-ribbons_6 PF07191.12 KKK14766.1 - 0.056 13.4 0.9 0.1 12.6 0.2 1.8 2 0 0 2 2 2 0 zinc-ribbons TT_ORF1 PF02956.14 KKK14766.1 - 1.1 7.8 11.5 1.7 7.2 11.5 1.2 1 0 0 1 1 1 0 TT viral orf 1 Apt1 PF10351.9 KKK14766.1 - 2.6 6.8 18.5 4 6.2 18.5 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain Dicty_REP PF05086.12 KKK14766.1 - 3.1 5.7 22.7 4.5 5.1 22.7 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein PPP4R2 PF09184.11 KKK14766.1 - 5.1 6.6 11.4 7.9 6.0 11.4 1.4 1 0 0 1 1 1 0 PPP4R2 SOG2 PF10428.9 KKK14766.1 - 6.3 5.9 31.8 12 4.9 31.8 1.5 1 0 0 1 1 1 0 RAM signalling pathway protein Ist1 PF03398.14 KKK14767.1 - 3.3e-44 150.7 0.2 5.2e-22 78.5 1.2 2.1 2 0 0 2 2 2 2 Regulator of Vps4 activity in the MVB pathway SAPS PF04499.15 KKK14767.1 - 0.00082 18.3 0.0 0.0011 17.9 0.0 1.1 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein DEAD_2 PF06733.15 KKK14768.1 - 1.8e-57 193.8 0.2 4.2e-57 192.6 0.2 1.7 1 0 0 1 1 1 1 DEAD_2 HBB PF06777.11 KKK14768.1 - 1.1e-49 168.7 3.6 4.5e-45 153.7 0.6 2.7 3 0 0 3 3 3 2 Helical and beta-bridge domain Helicase_C_2 PF13307.6 KKK14768.1 - 3.1e-44 151.2 0.0 8.9e-44 149.7 0.0 1.8 1 0 0 1 1 1 1 Helicase C-terminal domain ResIII PF04851.15 KKK14768.1 - 6.7e-05 22.9 0.1 0.0058 16.7 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KKK14768.1 - 0.0019 18.0 0.0 0.2 11.4 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF2075 PF09848.9 KKK14768.1 - 0.018 14.3 0.0 1.6 7.9 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) SNF2_N PF00176.23 KKK14768.1 - 0.043 12.5 0.0 0.33 9.6 0.0 2.1 1 1 0 1 1 1 0 SNF2 family N-terminal domain AAA_22 PF13401.6 KKK14768.1 - 0.058 13.7 2.6 4.7 7.5 0.0 3.5 4 0 0 4 4 4 0 AAA domain DUF2492 PF10678.9 KKK14768.1 - 0.097 13.0 0.2 0.37 11.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2492) RNA_pol_Rpb1_5 PF04998.17 KKK14769.1 - 1.4e-84 283.7 0.2 2.9e-84 282.7 0.2 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 KKK14769.1 - 5.1e-67 225.2 0.0 1.1e-66 224.1 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 KKK14769.1 - 9.6e-34 116.6 0.0 1.5e-32 112.7 0.0 2.9 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.12 KKK14769.1 - 2.6e-26 92.7 1.1 8.9e-25 87.7 0.5 2.9 2 1 0 2 2 2 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.17 KKK14769.1 - 7.5e-16 58.0 0.0 3.7e-15 55.8 0.0 2.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Gar1 PF04410.14 KKK14770.1 - 1.7e-46 157.8 0.1 5e-46 156.3 0.1 1.8 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region FA_desaturase PF00487.24 KKK14771.1 - 9.3e-15 55.2 26.7 9.3e-15 55.2 26.7 1.5 1 1 1 2 2 2 1 Fatty acid desaturase MFS_1 PF07690.16 KKK14772.1 - 1.2e-14 54.0 21.3 1.2e-14 54.0 21.3 2.3 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_3 PF05977.13 KKK14772.1 - 0.031 12.7 0.4 0.051 12.0 0.4 1.2 1 0 0 1 1 1 0 Transmembrane secretion effector LCM PF04072.14 KKK14773.1 - 2.3e-21 76.6 0.0 7.5e-21 74.9 0.0 1.9 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase C1_1 PF00130.22 KKK14773.1 - 0.13 12.2 1.0 0.28 11.1 1.0 1.5 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PRP3 PF08572.10 KKK14774.1 - 2.6e-74 249.7 5.3 5.3e-74 248.7 5.3 1.5 1 0 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.12 KKK14774.1 - 2.3e-47 160.8 0.2 2.3e-47 160.8 0.2 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1115) RNA_pol_Rpb5_C PF01191.19 KKK14782.1 - 3.2e-33 113.4 0.1 6.8e-33 112.4 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.14 KKK14782.1 - 4.3e-29 100.9 0.0 6.2e-29 100.4 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.12 KKK14782.1 - 0.021 14.8 0.0 0.064 13.3 0.0 1.7 2 0 0 2 2 2 0 Restriction endonuclease DUF2968 PF11180.8 KKK14783.1 - 0.00042 20.0 7.7 0.00042 20.0 7.7 4.8 3 1 2 5 5 5 1 Protein of unknown function (DUF2968) ABC_tran_CTD PF16326.5 KKK14783.1 - 0.001 19.3 3.3 0.001 19.3 3.3 5.5 2 2 3 5 5 5 1 ABC transporter C-terminal domain EzrA PF06160.12 KKK14783.1 - 0.0028 15.9 16.0 0.0028 15.9 16.0 3.5 2 1 2 4 4 4 2 Septation ring formation regulator, EzrA CENP-F_leu_zip PF10473.9 KKK14783.1 - 0.0033 17.5 42.2 0.13 12.3 4.5 4.3 2 1 2 4 4 4 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Hemagglutinin PF00509.18 KKK14783.1 - 0.67 8.3 9.2 0.075 11.4 0.9 2.1 1 1 1 2 2 2 0 Haemagglutinin Syntaxin-6_N PF09177.11 KKK14783.1 - 1.4 9.5 28.8 0.063 13.8 8.7 4.5 3 2 0 3 3 3 0 Syntaxin 6, N-terminal Baculo_p24 PF05073.12 KKK14783.1 - 1.8 8.4 18.3 0.093 12.5 3.1 2.9 3 0 0 3 3 3 0 Baculovirus P24 capsid protein APG6_N PF17675.1 KKK14783.1 - 2 9.0 64.2 6 7.4 20.1 5.2 2 1 2 4 4 4 0 Apg6 coiled-coil region Ribosomal_S26e PF01283.19 KKK14811.1 - 1.3e-52 176.7 8.1 1.5e-52 176.5 8.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e zf_CopZ PF18423.1 KKK14811.1 - 0.028 14.4 0.5 0.066 13.2 0.0 1.8 2 0 0 2 2 2 0 Zinc binding domain CBS PF00571.28 KKK14812.1 - 9.2e-35 118.9 5.6 5e-09 36.5 0.0 5.1 5 0 0 5 5 5 4 CBS domain PB1 PF00564.24 KKK14812.1 - 4.9e-07 29.6 0.4 1.5e-06 28.1 0.0 2.1 2 1 0 2 2 2 1 PB1 domain Importin_rep_4 PF18808.1 KKK14813.1 - 6.7e-33 112.8 1.1 6.7e-33 112.8 1.1 3.5 3 0 0 3 3 2 1 Importin repeat Importin_rep_5 PF18816.1 KKK14813.1 - 6.8e-24 83.9 0.5 6.8e-24 83.9 0.5 2.6 2 0 0 2 2 2 1 Importin repeat HEAT_EZ PF13513.6 KKK14813.1 - 9.3e-23 80.3 14.2 8.3e-11 42.2 0.3 9.1 8 2 1 9 9 9 2 HEAT-like repeat HEAT_2 PF13646.6 KKK14813.1 - 1.2e-16 60.8 6.9 0.00015 22.1 0.0 7.9 6 1 1 7 7 7 3 HEAT repeats HEAT PF02985.22 KKK14813.1 - 1.5e-15 56.0 12.7 0.00089 19.3 0.0 11.9 13 0 0 13 13 11 2 HEAT repeat Importin_rep_6 PF18829.1 KKK14813.1 - 1.8e-14 53.8 1.8 6.5e-14 52.0 0.4 2.6 2 0 0 2 2 2 1 Importin repeat 6 Vac14_Fab1_bd PF12755.7 KKK14813.1 - 1.1e-09 38.7 0.2 0.0085 16.7 0.0 6.4 4 2 4 8 8 7 2 Vacuolar 14 Fab1-binding region MMS19_C PF12460.8 KKK14813.1 - 2.2e-09 36.9 2.4 2.7e-06 26.8 0.3 5.1 5 1 1 6 6 6 1 RNAPII transcription regulator C-terminal DUF3385 PF11865.8 KKK14813.1 - 7.5e-09 35.7 0.7 0.052 13.5 0.1 6.2 4 2 1 6 6 6 2 Domain of unknown function (DUF3385) Cnd1 PF12717.7 KKK14813.1 - 2.7e-07 30.8 1.9 0.083 12.9 0.0 5.8 4 4 2 6 6 6 1 non-SMC mitotic condensation complex subunit 1 DRIM PF07539.12 KKK14813.1 - 8.3e-07 27.7 2.6 0.00097 17.6 0.8 3.9 2 2 1 4 4 4 2 Down-regulated in metastasis IFRD PF05004.13 KKK14813.1 - 2.8e-06 26.7 2.0 0.087 11.9 0.2 4.1 2 1 0 2 2 2 2 Interferon-related developmental regulator (IFRD) Arm PF00514.23 KKK14813.1 - 9.4e-06 25.5 3.4 0.016 15.2 0.0 4.8 5 0 0 5 5 4 1 Armadillo/beta-catenin-like repeat CLASP_N PF12348.8 KKK14813.1 - 3.4e-05 23.5 0.2 0.12 12.0 0.1 5.8 6 3 1 7 7 7 1 CLASP N terminal RIX1 PF08167.12 KKK14813.1 - 8.4e-05 22.4 0.1 0.015 15.1 0.1 3.6 2 1 0 2 2 2 1 rRNA processing/ribosome biogenesis IBN_N PF03810.19 KKK14813.1 - 0.00063 19.6 0.3 0.025 14.5 0.0 3.1 2 0 0 2 2 2 1 Importin-beta N-terminal domain RTP1_C1 PF10363.9 KKK14813.1 - 0.0022 18.2 1.9 0.59 10.3 0.6 4.8 4 1 2 6 6 6 1 Required for nuclear transport of RNA pol II C-terminus 1 DNA_alkylation PF08713.11 KKK14813.1 - 0.0074 16.0 0.0 0.07 12.8 0.0 2.7 2 0 0 2 2 2 1 DNA alkylation repair enzyme Adaptin_N PF01602.20 KKK14813.1 - 0.011 14.3 4.4 0.021 13.4 0.6 3.1 4 1 0 4 4 4 0 Adaptin N terminal region Cnd3 PF12719.7 KKK14813.1 - 0.067 12.4 0.1 3.2 6.9 0.0 3.5 2 1 1 3 3 3 0 Nuclear condensing complex subunits, C-term domain TFCD_C PF12612.8 KKK14813.1 - 0.075 12.9 0.1 2.2 8.1 0.0 3.1 2 1 0 2 2 2 0 Tubulin folding cofactor D C terminal DUF4042 PF13251.6 KKK14813.1 - 0.11 12.2 0.1 7.1 6.3 0.0 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4042) Telomere_reg-2 PF10193.9 KKK14813.1 - 0.13 12.7 5.8 0.2 12.1 0.5 3.7 4 0 0 4 4 4 0 Telomere length regulation protein Ribonuc_2-5A PF06479.12 KKK14813.1 - 0.14 12.3 0.0 0.72 10.0 0.1 2.2 2 0 0 2 2 1 0 Ribonuclease 2-5A V-ATPase_H_N PF03224.14 KKK14813.1 - 0.18 11.1 3.4 0.28 10.4 0.2 2.8 3 0 0 3 3 3 0 V-ATPase subunit H TAN PF11640.8 KKK14813.1 - 0.45 10.6 6.1 0.86 9.7 0.2 3.9 3 2 1 4 4 4 0 Telomere-length maintenance and DNA damage repair DUF2408 PF10303.9 KKK14814.1 - 1.7e-44 151.7 4.0 4.8e-27 95.2 0.7 5.0 3 2 1 4 4 4 4 Protein of unknown function (DUF2408) Snapin_Pallidin PF14712.6 KKK14814.1 - 0.031 14.7 4.0 0.21 12.1 0.5 3.4 4 0 0 4 4 4 0 Snapin/Pallidin Baculo_PEP_C PF04513.12 KKK14814.1 - 0.048 13.7 1.5 0.13 12.3 0.6 2.2 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Spc7 PF08317.11 KKK14814.1 - 0.048 12.5 0.3 0.075 11.9 0.3 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein CLZ PF16526.5 KKK14814.1 - 0.092 13.1 3.9 0.88 10.0 0.2 3.0 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Prefoldin_2 PF01920.20 KKK14814.1 - 0.12 12.4 0.8 20 5.2 0.0 3.1 1 1 2 3 3 3 0 Prefoldin subunit XhlA PF10779.9 KKK14814.1 - 0.21 11.8 2.2 49 4.2 0.0 3.5 2 1 1 3 3 3 0 Haemolysin XhlA Ribosomal_60s PF00428.19 KKK14815.1 - 1.6e-26 92.7 10.5 2e-26 92.4 10.5 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Shadoo PF14999.6 KKK14815.1 - 0.52 10.4 7.2 0.77 9.9 7.2 1.2 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective LRR_4 PF12799.7 KKK14816.1 - 5.2e-05 23.5 0.9 3.9 8.0 0.0 4.0 2 1 1 4 4 4 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KKK14816.1 - 0.0039 17.1 0.6 0.66 10.2 0.0 3.2 3 0 0 3 3 3 1 Leucine Rich repeat LRR_8 PF13855.6 KKK14816.1 - 0.64 9.8 3.1 17 5.3 0.1 3.5 2 1 1 3 3 3 0 Leucine rich repeat Gon7 PF08738.10 KKK14817.1 - 0.0073 16.4 3.9 0.53 10.4 1.0 2.4 2 1 0 2 2 2 2 Gon7 family Cpn60_TCP1 PF00118.24 KKK14818.1 - 1e-151 505.9 5.7 1.2e-151 505.7 5.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Rep_fac_C PF08542.11 KKK14818.1 - 0.0069 16.8 0.1 0.64 10.5 0.1 2.7 2 0 0 2 2 2 1 Replication factor C C-terminal domain Peptidase_C14 PF00656.22 KKK14819.1 - 2.3e-61 207.9 0.0 2.8e-61 207.6 0.0 1.1 1 0 0 1 1 1 1 Caspase domain CNH PF00780.22 KKK14820.1 - 1.2e-81 274.3 0.0 8.9e-81 271.5 0.0 2.0 2 0 0 2 2 2 1 CNH domain PH_5 PF15405.6 KKK14820.1 - 2.2e-41 141.1 0.0 7.1e-41 139.5 0.0 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.20 KKK14820.1 - 9.5e-38 130.2 0.0 1.9e-37 129.3 0.0 1.5 1 0 0 1 1 1 1 RhoGEF domain DEP PF00610.21 KKK14820.1 - 1.4e-14 53.9 0.0 3.2e-14 52.7 0.0 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) ATP-synt_C PF00137.21 KKK14821.1 - 3.5e-28 97.7 35.6 8e-17 61.3 13.2 2.1 2 0 0 2 2 2 2 ATP synthase subunit C Pkinase PF00069.25 KKK14822.1 - 1.6e-06 27.7 0.0 1.9e-06 27.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Arylesterase PF01731.20 KKK14842.1 - 0.00011 22.3 0.0 0.0017 18.5 0.0 2.7 3 0 0 3 3 3 1 Arylesterase Cwf_Cwc_15 PF04889.12 KKK14842.1 - 7 6.3 5.8 10 5.7 5.8 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein LETM1 PF07766.13 KKK14843.1 - 0.0022 17.4 0.0 0.067 12.5 0.1 2.2 1 1 1 2 2 2 2 LETM1-like protein ErmC PF06308.11 KKK14844.1 - 0.012 15.9 0.0 1.1 9.6 0.0 2.8 2 0 0 2 2 2 0 23S rRNA methylastransferase leader peptide (ErmCL) DUF3098 PF11297.8 KKK14844.1 - 0.073 12.7 2.4 10 5.8 0.2 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3098) MacB_PCD PF12704.7 KKK14844.1 - 0.088 13.2 1.7 6.4 7.1 0.0 3.3 3 0 0 3 3 3 0 MacB-like periplasmic core domain Bap31 PF05529.12 KKK14844.1 - 0.13 12.2 2.6 6 6.7 0.2 2.4 2 0 0 2 2 2 0 Bap31/Bap29 transmembrane region Sel1 PF08238.12 KKK14845.1 - 3.1e-40 135.7 27.5 2.8e-06 27.8 0.2 7.5 7 0 0 7 7 7 7 Sel1 repeat HTH_23 PF13384.6 KKK14845.1 - 0.14 12.0 0.2 0.31 10.9 0.2 1.6 1 0 0 1 1 1 0 Homeodomain-like domain TPR_6 PF13174.6 KKK14845.1 - 0.19 12.4 8.4 20 6.1 0.1 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.6 KKK14845.1 - 0.46 11.0 8.9 0.67 10.5 0.2 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat Pkinase PF00069.25 KKK14847.1 - 2.1e-69 233.9 0.0 3.3e-69 233.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK14847.1 - 3.6e-45 154.3 0.0 5.4e-45 153.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.18 KKK14847.1 - 3.7e-09 36.7 0.1 0.0017 18.5 0.0 3.0 2 0 0 2 2 2 2 POLO box duplicated region Kinase-like PF14531.6 KKK14847.1 - 9.2e-07 28.4 0.0 1.8e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KKK14847.1 - 0.056 12.8 0.0 0.098 12.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Chitin_synth_2 PF03142.15 KKK14848.1 - 2.9e-284 943.6 0.1 4.2e-284 943.0 0.1 1.2 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.6 KKK14848.1 - 4.6e-09 36.5 8.3 3.3e-08 33.7 8.3 2.5 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KKK14848.1 - 1e-08 35.4 0.0 4.6e-07 30.0 0.0 2.5 2 1 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KKK14848.1 - 3.7e-05 23.6 0.0 0.016 15.0 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 KKK14848.1 - 0.0012 18.4 0.0 0.0073 15.8 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase family 21 MFS_1 PF07690.16 KKK14848.1 - 7.4 5.4 17.2 0.87 8.4 8.3 2.6 3 0 0 3 3 3 0 Major Facilitator Superfamily Myosin_head PF00063.21 KKK14849.1 - 4.1e-242 805.2 3.1 5.4e-242 804.8 3.1 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 KKK14849.1 - 6.4e-53 179.2 0.0 1.5e-52 178.0 0.0 1.7 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding OPA3 PF07047.12 KKK14849.1 - 6.8e-47 158.3 1.9 1.7e-46 157.1 1.9 1.7 1 0 0 1 1 1 1 Optic atrophy 3 protein (OPA3) SH3_1 PF00018.28 KKK14849.1 - 1.1e-12 47.4 0.1 1.9e-12 46.6 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KKK14849.1 - 3.8e-08 32.9 0.0 9.5e-08 31.6 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 KKK14849.1 - 3.6e-06 26.7 0.0 8.5e-06 25.5 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain AAA_16 PF13191.6 KKK14849.1 - 0.0077 16.6 0.5 0.17 12.2 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain IQ PF00612.27 KKK14849.1 - 0.0084 15.8 8.7 0.35 10.8 0.6 2.7 2 0 0 2 2 2 2 IQ calmodulin-binding motif Med11 PF10280.9 KKK14849.1 - 0.017 15.6 0.7 0.017 15.6 0.7 2.5 2 0 0 2 2 2 0 Mediator complex protein AAA_22 PF13401.6 KKK14849.1 - 0.023 15.0 0.0 0.074 13.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain Hpr_kinase_C PF07475.12 KKK14849.1 - 0.081 12.4 1.5 4.2 6.9 0.0 2.8 3 0 0 3 3 3 0 HPr Serine kinase C-terminal domain NACHT PF05729.12 KKK14849.1 - 0.18 11.7 0.0 0.58 10.1 0.0 1.9 2 0 0 2 2 2 0 NACHT domain Laminin_II PF06009.12 KKK14865.1 - 0.0077 16.3 0.7 0.0096 15.9 0.7 1.2 1 0 0 1 1 1 1 Laminin Domain II MutS_IV PF05190.18 KKK14865.1 - 0.09 13.1 1.1 0.14 12.5 1.1 1.3 1 0 0 1 1 1 0 MutS family domain IV Phage_1_1 PF08200.11 KKK14865.1 - 0.36 11.3 2.6 0.29 11.6 0.7 1.9 2 0 0 2 2 2 0 Bacteriophage 1.1 Protein VitK2_biosynth PF02621.14 KKK14865.1 - 0.57 9.6 3.5 0.77 9.2 3.5 1.1 1 0 0 1 1 1 0 Menaquinone biosynthesis FAD_binding_4 PF01565.23 KKK14866.1 - 5.3e-33 113.7 7.1 2.9e-32 111.3 7.6 2.0 3 0 0 3 3 3 1 FAD binding domain BBE PF08031.12 KKK14866.1 - 1.3e-06 28.3 0.1 2.7e-06 27.4 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like ADP_ribosyl_GH PF03747.14 KKK14867.1 - 6.9e-53 180.3 0.0 9.6e-53 179.8 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase MFS_1 PF07690.16 KKK14867.1 - 9.6e-31 107.0 56.6 1.3e-29 103.3 18.5 2.7 2 1 1 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.13 KKK14867.1 - 1.3e-16 60.2 13.6 2.5e-16 59.2 13.6 1.5 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF1206 PF06724.11 KKK14867.1 - 0.025 14.7 2.8 0.17 12.0 0.3 3.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1206) DUF4668 PF15701.5 KKK14867.1 - 0.028 14.2 1.5 0.54 10.1 0.1 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4668) EFhand_Ca_insen PF08726.10 KKK14867.1 - 0.07 13.2 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Ca2+ insensitive EF hand Ank_4 PF13637.6 KKK14868.1 - 1.2e-23 83.1 0.6 1.1e-08 35.4 0.0 3.7 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KKK14868.1 - 1.1e-22 80.5 0.0 2.2e-11 44.2 0.0 2.5 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.30 KKK14868.1 - 1.5e-19 69.5 1.7 0.00046 20.5 0.0 4.9 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 KKK14868.1 - 2.2e-19 69.3 4.3 1.1e-05 25.6 0.0 3.7 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KKK14868.1 - 1e-17 62.4 0.2 0.0013 19.1 0.0 4.7 4 0 0 4 4 4 4 Ankyrin repeat bZIP_2 PF07716.15 KKK14868.1 - 2e-05 24.6 0.7 3.1e-05 24.0 0.7 1.2 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 KKK14868.1 - 4.8e-05 23.4 3.8 8.1e-05 22.6 3.8 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 KKK14868.1 - 0.11 13.1 3.9 0.18 12.3 3.9 1.3 1 0 0 1 1 1 0 bZIP Maf transcription factor adh_short PF00106.25 KKK14869.1 - 8.7e-23 80.8 0.0 1.1e-22 80.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KKK14869.1 - 1.4e-15 57.5 0.0 1.8e-15 57.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KKK14869.1 - 3.9e-08 33.4 0.0 5.3e-08 33.0 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KKK14869.1 - 0.0059 16.1 0.5 0.025 14.1 0.5 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KKK14869.1 - 0.061 13.2 0.1 0.087 12.7 0.1 1.3 1 0 0 1 1 1 0 NAD(P)H-binding Pyr_redox_2 PF07992.14 KKK14871.1 - 5.8e-33 114.4 0.1 7.6e-33 114.0 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KKK14871.1 - 5.9e-14 52.4 0.2 2.9e-08 34.2 0.1 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KKK14871.1 - 1.1e-07 31.4 0.3 3.1e-05 23.4 0.2 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KKK14871.1 - 5.5e-06 26.4 1.6 0.24 11.4 0.0 4.0 4 0 0 4 4 4 2 FAD-NAD(P)-binding TrkA_N PF02254.18 KKK14871.1 - 4.8e-05 23.6 0.6 0.24 11.7 0.0 3.1 3 1 1 4 4 4 2 TrkA-N domain DAO PF01266.24 KKK14871.1 - 0.00029 20.5 3.6 2.2 7.8 0.1 3.6 3 1 1 4 4 4 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KKK14871.1 - 0.00035 19.7 0.4 0.03 13.4 0.0 2.3 2 0 0 2 2 2 2 Lycopene cyclase protein K_oxygenase PF13434.6 KKK14871.1 - 0.0018 17.5 0.0 0.56 9.3 0.1 2.5 2 1 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 KKK14871.1 - 0.0042 16.3 3.5 0.18 11.0 0.2 2.5 3 0 0 3 3 3 2 Thi4 family DUF1188 PF06690.11 KKK14871.1 - 0.1 12.1 0.1 3.4 7.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1188) NmrA PF05368.13 KKK14872.1 - 2.8e-14 53.3 0.0 6.8e-14 52.0 0.0 1.6 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KKK14872.1 - 2.2e-12 47.3 0.0 3.3e-12 46.7 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KKK14872.1 - 0.093 11.7 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DUF829 PF05705.14 KKK14873.1 - 2e-56 191.6 0.0 2.3e-56 191.4 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) PapG_N PF03627.13 KKK14874.1 - 0.13 11.9 0.0 0.16 11.6 0.0 1.1 1 0 0 1 1 1 0 PapG carbohydrate binding domain IBR PF01485.21 KKK14875.1 - 1.3e-05 25.3 4.8 1.3e-05 25.3 4.8 5.3 5 0 0 5 5 5 1 IBR domain, a half RING-finger domain VWA_2 PF13519.6 KKK14875.1 - 0.0061 17.2 0.0 0.015 15.9 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain Zn_Tnp_IS91 PF14319.6 KKK14875.1 - 0.0079 16.2 8.4 0.0079 16.2 8.4 4.2 4 1 1 5 5 5 1 Transposase zinc-binding domain Pec_lyase_C PF00544.19 KKK14876.1 - 8.2e-11 41.9 7.3 2.1e-09 37.3 7.3 2.4 1 1 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 KKK14876.1 - 2.1e-05 24.4 21.7 0.00073 19.4 6.5 2.3 1 1 1 2 2 2 2 Right handed beta helix region FAD_binding_4 PF01565.23 KKK14878.1 - 3.9e-32 110.9 7.2 6.7e-32 110.1 7.2 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KKK14878.1 - 8.2e-09 35.4 0.0 1.7e-08 34.4 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like GST_N PF02798.20 KKK14879.1 - 3.4e-12 46.5 0.0 5.8e-12 45.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KKK14879.1 - 1.2e-11 44.7 0.0 1.9e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KKK14879.1 - 1.1e-08 35.0 0.7 1.4e-08 34.7 0.1 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KKK14879.1 - 1.3e-07 31.8 0.0 2.9e-07 30.6 0.0 1.5 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KKK14879.1 - 2.8e-07 30.8 0.0 5.4e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KKK14879.1 - 8.2e-05 22.8 0.0 0.00014 22.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.4 KKK14879.1 - 0.0029 18.3 0.0 0.006 17.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain Romo1 PF10247.9 KKK14880.1 - 0.0044 17.4 0.2 0.0099 16.2 0.2 1.6 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 SKG6 PF08693.10 KKK14880.1 - 0.026 13.9 3.7 0.05 13.0 3.7 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain LapA_dom PF06305.11 KKK14880.1 - 0.054 13.3 0.5 0.054 13.3 0.5 1.8 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Gram_pos_anchor PF00746.21 KKK14880.1 - 0.88 9.6 3.1 2.1 8.3 3.1 1.7 1 0 0 1 1 1 0 LPXTG cell wall anchor motif Lipase_GDSL_2 PF13472.6 KKK14881.1 - 4.3e-20 72.9 0.0 8.9e-20 71.8 0.0 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KKK14881.1 - 2.3e-11 44.1 0.0 3.6e-11 43.4 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase DsrH PF04077.12 KKK14881.1 - 0.074 13.2 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 DsrH like protein 4HBT_3 PF13622.6 KKK14882.1 - 2.5e-48 165.5 0.2 2.9e-48 165.3 0.2 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.22 KKK14882.1 - 0.016 15.5 0.1 0.064 13.6 0.0 1.9 2 0 0 2 2 2 0 Thioesterase superfamily G-alpha PF00503.20 KKK14884.1 - 1.4e-124 415.9 0.9 1.6e-124 415.7 0.9 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KKK14884.1 - 2.3e-15 56.5 1.6 2.4e-10 40.1 0.1 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family zf-CHC2 PF01807.20 KKK14884.1 - 6.9e-05 22.6 0.0 0.00033 20.4 0.0 2.0 2 0 0 2 2 2 1 CHC2 zinc finger Gtr1_RagA PF04670.12 KKK14884.1 - 0.0028 17.1 3.1 0.086 12.2 0.1 2.5 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region AAA_29 PF13555.6 KKK14884.1 - 0.013 15.2 0.0 0.034 13.9 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Roc PF08477.13 KKK14884.1 - 0.017 15.3 0.7 2.4 8.4 0.0 2.9 2 1 1 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase MCM PF00493.23 KKK14884.1 - 0.055 12.6 0.1 0.12 11.5 0.1 1.5 1 1 0 1 1 1 0 MCM P-loop domain AAA_23 PF13476.6 KKK14884.1 - 0.06 13.8 0.1 0.13 12.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain GTP_EFTU PF00009.27 KKK14884.1 - 0.084 12.4 0.0 1.2 8.7 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain FtsK_SpoIIIE PF01580.18 KKK14884.1 - 0.13 11.6 0.0 0.28 10.5 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family MMR_HSR1 PF01926.23 KKK14884.1 - 0.13 12.3 0.1 8.4 6.5 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase DUF1771 PF08590.10 KKK14885.1 - 1.1e-26 93.0 8.2 2.3e-26 92.0 8.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Smr PF01713.21 KKK14885.1 - 0.0065 16.8 0.5 0.015 15.7 0.2 1.7 2 0 0 2 2 2 1 Smr domain Glyco_transf_92 PF01697.27 KKK14885.1 - 0.053 13.2 1.0 0.58 9.8 0.1 2.1 2 0 0 2 2 2 0 Glycosyltransferase family 92 DUF4407 PF14362.6 KKK14885.1 - 0.058 12.7 3.6 0.069 12.5 3.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Connexin43 PF03508.13 KKK14885.1 - 0.17 11.5 0.5 0.17 11.5 0.5 2.2 2 0 0 2 2 2 0 Gap junction alpha-1 protein (Cx43) CBF PF03914.17 KKK14887.1 - 2e-54 184.2 6.2 3.9e-54 183.2 0.0 3.1 2 0 0 2 2 2 1 CBF/Mak21 family LMBR1 PF04791.16 KKK14887.1 - 0.15 11.0 1.9 0.27 10.1 1.9 1.5 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF2477 PF10631.9 KKK14887.1 - 1.1 9.9 5.2 0.36 11.5 1.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2477) tRNA-synt_2b PF00587.25 KKK14888.1 - 4.3e-30 105.0 0.0 7.2e-30 104.3 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 KKK14888.1 - 1.6e-12 47.4 0.1 4.8e-12 45.9 0.1 1.8 2 0 0 2 2 2 1 Anticodon binding domain GCV_T PF01571.21 KKK14889.1 - 1.6e-79 266.9 0.0 2.4e-79 266.3 0.0 1.3 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 KKK14889.1 - 6.2e-15 54.9 0.2 1.3e-14 53.8 0.2 1.6 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain Aa_trans PF01490.18 KKK14890.1 - 3.1e-29 101.9 33.8 3.9e-29 101.6 33.8 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein ILVD_EDD PF00920.21 KKK14918.1 - 0.007 15.0 0.0 0.0087 14.7 0.0 1.1 1 0 0 1 1 1 1 Dehydratase family tRNA-synt_1c PF00749.21 KKK14919.1 - 9.1e-92 307.3 0.0 1.2e-91 307.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain DnaJ_C PF01556.18 KKK14920.1 - 1.9e-38 131.8 0.2 3.3e-38 131.1 0.2 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KKK14920.1 - 3.9e-22 78.1 1.6 7.3e-22 77.3 1.6 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KKK14920.1 - 1.3e-13 51.1 16.6 2.4e-13 50.2 16.6 1.5 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 KKK14920.1 - 0.021 14.7 10.0 0.8 9.7 1.5 2.5 2 0 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein zf-RING_10 PF16685.5 KKK14920.1 - 0.043 13.9 5.3 0.3 11.2 0.4 2.2 2 0 0 2 2 2 0 zinc RING finger of MSL2 RseC_MucC PF04246.12 KKK14920.1 - 0.085 12.8 0.2 0.085 12.8 0.2 1.9 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC DUF1356 PF07092.12 KKK14920.1 - 0.11 11.8 5.2 1.3 8.2 0.5 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1356) Cas_TM1802 PF09484.10 KKK14920.1 - 5.2 5.7 4.8 7.4 5.2 4.8 1.2 1 0 0 1 1 1 0 CRISPR-associated protein TM1802 (cas_TM1802) HypA PF01155.19 KKK14920.1 - 5.7 7.0 12.0 12 6.0 2.0 2.4 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA JAB PF01398.21 KKK14921.1 - 4.4e-29 100.8 0.0 8.1e-29 100.0 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease CSN5_C PF18323.1 KKK14921.1 - 8.3e-22 77.9 0.1 1.7e-21 76.9 0.1 1.5 1 0 0 1 1 1 1 Cop9 signalosome subunit 5 C-terminal domain Prok-JAB PF14464.6 KKK14921.1 - 0.00036 20.3 0.0 0.00078 19.2 0.0 1.6 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain MAP65_ASE1 PF03999.12 KKK14922.1 - 8.6e-76 255.9 0.1 1.1e-75 255.6 0.1 1.3 1 0 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) ApoLp-III PF07464.11 KKK14922.1 - 0.0013 18.8 1.5 0.0043 17.2 0.8 2.2 1 1 0 1 1 1 1 Apolipophorin-III precursor (apoLp-III) Baculo_PEP_C PF04513.12 KKK14922.1 - 0.086 12.9 2.9 0.85 9.7 2.0 3.0 5 0 0 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fzo_mitofusin PF04799.13 KKK14922.1 - 0.5 9.9 2.0 1.7 8.2 2.0 1.9 1 0 0 1 1 1 0 fzo-like conserved region VGPC1_C PF16799.5 KKK14922.1 - 5.5 7.0 6.2 17 5.5 0.3 3.3 3 0 0 3 3 3 0 C-terminal membrane-localisation domain of ion-channel, VCN1 Fungal_trans PF04082.18 KKK14923.1 - 3.5e-19 68.9 4.6 5.3e-19 68.3 4.6 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.6 KKK14923.1 - 7.1e-07 29.4 14.9 7.6e-05 23.0 5.5 3.0 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.26 KKK14923.1 - 0.016 15.6 19.3 0.039 14.4 5.3 3.4 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_3rep PF18868.1 KKK14923.1 - 0.04 14.6 0.7 3 8.5 0.1 2.5 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_4 PF13894.6 KKK14923.1 - 0.21 12.5 19.6 0.26 12.2 4.1 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger Zn-ribbon_8 PF09723.10 KKK14923.1 - 1.4 9.1 3.7 5.8 7.1 3.7 2.1 1 0 0 1 1 1 0 Zinc ribbon domain zf-C2H2_jaz PF12171.8 KKK14923.1 - 3.1 8.2 7.4 1.3 9.3 3.7 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding RasGEF PF00617.19 KKK14924.1 - 1.2e-59 201.5 0.1 2e-59 200.7 0.1 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 KKK14924.1 - 1.3e-29 102.5 0.1 2.9e-29 101.4 0.1 1.6 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_1 PF00018.28 KKK14924.1 - 5.3e-16 58.0 0.1 1.1e-15 57.0 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KKK14924.1 - 1.5e-13 50.4 0.1 4.3e-13 48.9 0.1 1.9 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KKK14924.1 - 1.7e-11 43.6 0.1 4e-11 42.4 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain WW PF00397.26 KKK14924.1 - 0.0079 16.3 0.0 0.015 15.3 0.0 1.5 1 0 0 1 1 1 1 WW domain UPRTase PF14681.6 KKK14925.1 - 1.3e-71 240.3 0.0 1.5e-71 240.1 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 KKK14925.1 - 2.6e-05 23.8 0.0 4.3e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain CRCB PF02537.15 KKK14926.1 - 1.4e-38 131.1 11.8 1.4e-22 79.8 8.0 2.3 2 0 0 2 2 2 2 CrcB-like protein, Camphor Resistance (CrcB) RNA_pol_Rpc4 PF05132.14 KKK14929.1 - 7.9e-33 114.0 0.0 7.9e-33 114.0 0.0 4.2 1 1 2 4 4 4 1 RNA polymerase III RPC4 DUF1524 PF07510.11 KKK14934.1 - 1.5e-10 41.1 0.0 1.8e-10 40.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1524) GH-E PF14410.6 KKK14934.1 - 0.002 18.5 0.0 0.015 15.6 0.0 2.0 2 0 0 2 2 2 1 HNH/ENDO VII superfamily nuclease with conserved GHE residues HNH_4 PF13395.6 KKK14934.1 - 0.09 12.7 0.9 0.42 10.6 0.9 2.0 1 1 0 1 1 1 0 HNH endonuclease MFS_1 PF07690.16 KKK14935.1 - 1.3e-40 139.4 46.3 1.3e-40 139.4 46.3 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KKK14935.1 - 1.7e-06 27.2 24.2 1.7e-06 27.2 24.2 3.2 2 1 0 2 2 2 1 Sugar (and other) transporter PsbH PF00737.20 KKK14935.1 - 0.78 9.5 4.3 0.89 9.3 0.1 3.1 2 0 0 2 2 2 0 Photosystem II 10 kDa phosphoprotein Sugar_tr PF00083.24 KKK14936.1 - 3.9e-114 382.0 23.3 4.6e-114 381.8 23.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKK14936.1 - 3.5e-23 82.1 40.2 1.6e-22 80.0 24.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Abhydrolase_2 PF02230.16 KKK14937.1 - 2e-25 89.9 0.0 3e-18 66.4 0.0 2.1 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 KKK14937.1 - 0.067 12.4 0.1 1.4 8.1 0.0 2.4 2 1 1 3 3 3 0 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KKK14937.1 - 0.087 12.3 0.0 0.85 9.1 0.0 2.3 3 0 0 3 3 3 0 Prolyl oligopeptidase family AA_permease PF00324.21 KKK14938.1 - 2.3e-118 395.8 45.8 2.6e-118 395.7 45.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KKK14938.1 - 2e-40 138.9 48.6 3.4e-40 138.2 48.6 1.3 1 0 0 1 1 1 1 Amino acid permease Glyco_hydro_61 PF03443.14 KKK14939.1 - 0.043 13.8 0.0 0.12 12.3 0.0 1.6 1 1 0 1 1 1 0 Glycosyl hydrolase family 61 Redoxin PF08534.10 KKK14940.1 - 2.7e-37 127.8 0.0 3e-37 127.6 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 KKK14940.1 - 1.2e-10 41.4 0.0 1.5e-10 41.1 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family AhpC-TSA_2 PF13911.6 KKK14940.1 - 0.15 12.2 0.0 0.22 11.7 0.0 1.3 1 0 0 1 1 1 0 AhpC/TSA antioxidant enzyme GPI2 PF06432.11 KKK14941.1 - 2.3e-133 443.9 1.2 2.9e-133 443.6 1.2 1.1 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase DUF4716 PF15837.5 KKK14941.1 - 0.33 11.0 4.2 0.45 10.6 2.3 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4716) Glyco_hydro_18 PF00704.28 KKK14942.1 - 2.2e-81 274.0 0.1 2.6e-81 273.8 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 KKK14942.1 - 2.2e-07 31.2 19.9 4.2e-07 30.3 19.9 1.5 1 0 0 1 1 1 1 Chitin recognition protein Glyco_hydro_66 PF13199.6 KKK14942.1 - 0.069 11.8 0.0 0.13 10.9 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 66 Fumble PF03630.14 KKK14943.1 - 8e-145 482.1 0.8 9.9e-145 481.8 0.8 1.1 1 0 0 1 1 1 1 Fumble DUF2796 PF10986.8 KKK14943.1 - 0.0044 17.0 20.2 0.0071 16.3 20.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2796) Zip PF02535.22 KKK14943.1 - 0.012 14.8 5.0 0.017 14.4 5.0 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DUF2457 PF10446.9 KKK14943.1 - 0.064 12.4 12.0 0.09 11.9 12.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CKAP2_C PF15297.6 KKK14943.1 - 0.095 11.8 0.4 0.14 11.2 0.4 1.1 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus SelP_N PF04592.14 KKK14943.1 - 0.99 8.8 18.7 1.6 8.0 18.7 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region NicO PF03824.16 KKK14943.1 - 1.1 8.6 7.4 1.7 7.9 7.4 1.2 1 0 0 1 1 1 0 High-affinity nickel-transport protein NOA36 PF06524.12 KKK14943.1 - 4.9 6.4 10.9 7 5.9 10.9 1.1 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 KKK14943.1 - 6.9 4.6 8.9 9.6 4.2 8.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi FYDLN_acid PF09538.10 KKK14943.1 - 7.2 7.3 11.0 14 6.4 11.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) HNH_2 PF13391.6 KKK14944.1 - 8.5e-05 22.6 0.0 0.00021 21.3 0.0 1.7 1 0 0 1 1 1 1 HNH endonuclease Polysacc_deac_1 PF01522.21 KKK14945.1 - 2.4e-19 69.5 0.0 3.8e-19 68.8 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.9 KKK14945.1 - 0.00062 19.5 0.0 0.0013 18.4 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) SIR2 PF02146.17 KKK14945.1 - 0.2 11.6 0.0 0.33 10.8 0.0 1.3 1 0 0 1 1 1 0 Sir2 family DEAD PF00270.29 KKK14946.1 - 4.9e-45 153.4 0.0 1.4e-44 151.9 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KKK14946.1 - 3.4e-14 53.1 0.0 3.2e-13 50.0 0.0 2.6 2 1 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 KKK14946.1 - 0.0008 18.2 0.0 0.0011 17.7 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.15 KKK14946.1 - 0.0087 16.1 0.0 0.018 15.1 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Fringe PF02434.16 KKK14948.1 - 3.3e-09 36.5 0.1 7.2e-08 32.2 0.0 2.4 2 1 0 2 2 2 1 Fringe-like PAN_3 PF08277.12 KKK14948.1 - 0.078 12.8 0.5 0.15 11.9 0.5 1.4 1 0 0 1 1 1 0 PAN-like domain DUF604 PF04646.12 KKK14948.1 - 0.12 11.7 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF604 DFP PF04127.15 KKK14949.1 - 2.5e-15 56.8 0.0 6.3e-07 29.4 0.0 2.3 2 0 0 2 2 2 2 DNA / pantothenate metabolism flavoprotein FA_desaturase PF00487.24 KKK14950.1 - 2.1e-26 93.3 29.1 3.1e-26 92.7 29.1 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 KKK14950.1 - 1.1e-09 38.3 0.0 2.3e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain SCO1-SenC PF02630.14 KKK14951.1 - 2.5e-47 160.2 0.1 4.2e-47 159.4 0.1 1.4 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.21 KKK14951.1 - 0.0002 21.3 0.0 0.00049 20.0 0.0 1.7 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 KKK14951.1 - 0.064 13.6 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like Redoxin PF08534.10 KKK14951.1 - 0.18 11.5 0.0 0.64 9.7 0.0 2.0 1 1 0 1 1 1 0 Redoxin MoaE PF02391.17 KKK14952.1 - 6e-36 123.2 0.2 7.6e-36 122.8 0.2 1.1 1 0 0 1 1 1 1 MoaE protein VIR_N PF15912.5 KKK14952.1 - 0.22 11.1 4.1 0.28 10.8 4.1 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal Cytochrom_B558a PF05038.13 KKK14952.1 - 3.6 7.1 11.2 1.5 8.4 0.0 2.2 2 0 0 2 2 2 0 Cytochrome Cytochrome b558 alpha-subunit KH_dom-like PF14714.6 KKK14953.1 - 0.09 13.1 0.1 0.3 11.4 0.1 1.8 1 1 1 2 2 2 0 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal Fungal_trans PF04082.18 KKK14954.1 - 1.5e-19 70.1 0.0 3.9e-19 68.7 0.0 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Iso_dh PF00180.20 KKK14955.1 - 1.1e-87 294.5 0.0 1.2e-87 294.3 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Acatn PF13000.7 KKK14958.1 - 2.9e-164 547.6 14.4 2.2e-82 277.3 7.0 3.1 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 MFS_1_like PF12832.7 KKK14958.1 - 0.03 13.2 8.2 0.061 12.2 8.2 1.4 1 0 0 1 1 1 0 MFS_1 like family Yae1_N PF09811.9 KKK14959.1 - 4.9e-12 45.3 0.2 9.3e-12 44.4 0.2 1.5 1 0 0 1 1 1 1 Essential protein Yae1, N terminal SurE PF01975.17 KKK14959.1 - 0.11 12.3 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Survival protein SurE Abhydrolase_3 PF07859.13 KKK14961.1 - 1e-41 143.2 0.0 1.2e-41 142.9 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KKK14961.1 - 6.7e-09 35.5 0.0 2.2e-08 33.8 0.0 1.7 1 1 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.18 KKK14961.1 - 1.4e-06 28.0 0.0 0.0025 17.4 0.0 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family Peptidase_S15 PF02129.18 KKK14961.1 - 0.0014 18.2 0.0 0.0048 16.5 0.0 1.8 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) COesterase PF00135.28 KKK14961.1 - 0.0024 16.8 0.0 0.0074 15.2 0.0 1.6 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_6 PF12697.7 KKK14961.1 - 0.0034 18.0 1.3 0.047 14.3 1.2 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.12 KKK14961.1 - 0.0095 14.6 0.0 1.5 7.4 0.0 2.1 2 0 0 2 2 2 2 Acetyl xylan esterase (AXE1) BAAT_C PF08840.11 KKK14961.1 - 0.013 15.4 0.0 0.022 14.7 0.0 1.4 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_2 PF02230.16 KKK14961.1 - 0.045 13.6 0.0 0.091 12.5 0.0 1.5 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Chlorophyllase2 PF12740.7 KKK14961.1 - 0.16 10.9 0.0 0.23 10.3 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme Atg29_N PF18388.1 KKK14962.1 - 4.2e-29 100.1 1.2 7.7e-29 99.3 1.2 1.5 1 0 0 1 1 1 1 Atg29 N-terminal domain CENP-O PF09496.10 KKK14963.1 - 2e-66 224.0 0.1 9.8e-66 221.8 0.0 1.9 2 0 0 2 2 2 1 Cenp-O kinetochore centromere component DUF4554 PF15091.6 KKK14964.1 - 0.072 12.0 3.9 0.13 11.2 3.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) AMP-binding PF00501.28 KKK14977.1 - 5.6e-72 242.6 0.0 6.8e-72 242.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 KKK14977.1 - 6.3e-19 67.6 0.6 3e-17 62.2 0.2 2.6 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 KKK14977.1 - 2.8e-14 53.8 0.1 9.3e-14 52.2 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain HTH_DeoR PF08220.12 KKK14977.1 - 0.089 12.6 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain GPP34 PF05719.11 KKK14977.1 - 0.1 12.6 0.1 0.22 11.5 0.1 1.5 1 0 0 1 1 1 0 Golgi phosphoprotein 3 (GPP34) Patatin PF01734.22 KKK14979.1 - 1.7e-16 61.1 0.2 3.7e-16 59.9 0.1 1.6 2 0 0 2 2 2 1 Patatin-like phospholipase SHMT PF00464.19 KKK14980.1 - 4.1e-197 654.6 0.0 4.8e-197 654.4 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase p450 PF00067.22 KKK15010.1 - 3.1e-55 187.7 0.0 4.2e-55 187.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 MARVEL PF01284.23 KKK15026.1 - 7.8e-09 35.7 7.1 1.1e-08 35.3 7.1 1.2 1 0 0 1 1 1 1 Membrane-associating domain DUF4013 PF13197.6 KKK15026.1 - 0.0031 17.4 6.8 0.88 9.4 0.2 2.8 2 1 0 2 2 2 2 Protein of unknown function (DUF4013) TMEM223 PF14640.6 KKK15026.1 - 0.0062 16.7 0.1 0.0096 16.1 0.1 1.2 1 0 0 1 1 1 1 Transmembrane protein 223 SecG PF03840.14 KKK15026.1 - 0.024 14.7 0.7 0.27 11.3 0.1 2.7 3 0 0 3 3 3 0 Preprotein translocase SecG subunit CbtA PF09490.10 KKK15026.1 - 0.058 13.2 1.6 0.14 11.9 1.2 1.8 1 1 1 2 2 2 0 Probable cobalt transporter subunit (CbtA) CAF1 PF04857.20 KKK15027.1 - 1.2e-21 77.2 0.0 2e-10 40.4 0.0 2.1 2 0 0 2 2 2 2 CAF1 family ribonuclease NDUF_B12 PF08122.12 KKK15028.1 - 1.5e-27 95.4 1.6 2e-27 95.0 1.6 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family TPR_2 PF07719.17 KKK15029.1 - 1.7e-05 24.5 2.7 1.7 9.0 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KKK15029.1 - 0.00054 19.7 3.4 3.9 7.5 0.2 3.7 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 KKK15029.1 - 0.0021 18.5 0.4 0.039 14.4 0.0 2.9 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 KKK15029.1 - 0.0039 17.1 1.8 1.4 9.1 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 KKK15029.1 - 0.0043 17.3 7.2 0.52 10.6 0.1 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 KKK15029.1 - 0.36 11.5 12.1 1.4 9.6 0.5 3.4 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 KKK15029.1 - 0.46 11.4 8.9 5.1 8.2 0.1 3.8 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 KKK15029.1 - 2.6 8.1 7.6 22 5.1 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Cu_amine_oxid PF01179.20 KKK15030.1 - 6.8e-157 522.6 0.0 9.1e-157 522.2 0.0 1.2 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 KKK15030.1 - 3.9e-23 81.7 1.0 6.2e-22 77.9 0.1 2.4 1 1 1 2 2 2 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.16 KKK15030.1 - 4.6e-14 52.4 0.0 8.4e-14 51.6 0.0 1.4 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Sugar_tr PF00083.24 KKK15031.1 - 6.3e-47 160.5 22.2 1.5e-46 159.2 22.2 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKK15031.1 - 4.3e-19 68.6 32.9 4.3e-19 68.6 32.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Acetyltransf_1 PF00583.25 KKK15031.1 - 0.0073 16.5 0.2 0.02 15.1 0.2 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KKK15031.1 - 0.044 13.7 0.0 0.095 12.6 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KKK15031.1 - 0.12 12.8 0.1 0.47 10.9 0.1 2.0 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DAO PF01266.24 KKK15032.1 - 6.8e-31 108.1 0.3 1.3e-30 107.2 0.3 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KKK15032.1 - 6.1e-05 23.5 0.0 0.0017 18.8 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KKK15032.1 - 6.2e-05 23.1 0.1 0.00015 21.9 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KKK15032.1 - 8.3e-05 22.0 0.0 0.00038 19.8 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 KKK15032.1 - 0.00013 22.3 0.0 0.00024 21.5 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding FAD_binding_2 PF00890.24 KKK15032.1 - 0.0012 18.1 0.1 0.0027 16.9 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain AlaDh_PNT_C PF01262.21 KKK15032.1 - 0.0027 17.0 0.0 0.0045 16.3 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ApbA PF02558.16 KKK15032.1 - 0.008 15.8 0.0 0.016 14.9 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA FAD_binding_3 PF01494.19 KKK15032.1 - 0.014 14.6 0.0 0.025 13.8 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain 3HCDH_N PF02737.18 KKK15032.1 - 0.016 15.1 0.0 0.025 14.5 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 KKK15032.1 - 0.055 13.5 0.0 0.095 12.8 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase GIDA PF01134.22 KKK15032.1 - 0.1 11.6 0.1 0.15 11.1 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Glu_dehyd_C PF16912.5 KKK15032.1 - 0.12 11.9 0.0 0.27 10.7 0.0 1.5 2 0 0 2 2 2 0 Glucose dehydrogenase C-terminus UDPG_MGDP_dh_N PF03721.14 KKK15032.1 - 0.13 11.8 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Sacchrp_dh_NADP PF03435.18 KKK15032.1 - 0.21 11.8 0.0 0.38 11.0 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain FAD_binding_3 PF01494.19 KKK15033.1 - 3.4e-10 39.7 0.0 0.00015 21.2 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Trp_halogenase PF04820.14 KKK15033.1 - 2.4e-06 26.7 0.0 0.0041 16.0 0.0 2.8 3 0 0 3 3 3 2 Tryptophan halogenase DAO PF01266.24 KKK15033.1 - 7.6e-05 22.4 0.1 0.00013 21.7 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KKK15033.1 - 9.7e-05 22.5 0.0 0.00029 21.0 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KKK15033.1 - 0.00055 19.3 0.0 0.014 14.6 0.0 2.1 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KKK15033.1 - 0.00093 19.2 0.0 0.0061 16.6 0.1 2.1 2 0 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.17 KKK15033.1 - 0.015 14.6 0.0 0.023 14.0 0.0 1.2 1 0 0 1 1 1 0 Thi4 family FAD_binding_2 PF00890.24 KKK15033.1 - 0.068 12.2 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain MCRA PF06100.11 KKK15033.1 - 0.16 10.7 0.0 0.22 10.3 0.0 1.1 1 0 0 1 1 1 0 MCRA family Pec_lyase_C PF00544.19 KKK15034.1 - 3.7e-47 160.7 9.3 5e-47 160.2 9.3 1.1 1 0 0 1 1 1 1 Pectate lyase Glyco_hydro_18 PF00704.28 KKK15035.1 - 3.4e-10 40.1 0.0 5.2e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 LOR PF04525.12 KKK15036.1 - 9.7e-08 31.8 0.0 7.4e-07 28.9 0.0 2.0 1 1 0 1 1 1 1 LURP-one-related Lipase_GDSL PF00657.22 KKK15037.1 - 5.2e-12 46.2 0.0 7.2e-12 45.7 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 KKK15037.1 - 3.4e-05 24.3 2.4 6.9e-05 23.3 2.4 1.8 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family AMP-binding PF00501.28 KKK15038.1 - 2.1e-75 253.9 0.0 2.7e-75 253.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KKK15038.1 - 8e-14 52.4 0.2 1.9e-13 51.2 0.2 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain WD40 PF00400.32 KKK15039.1 - 1.9e-17 63.3 0.3 0.00074 20.3 0.0 7.5 8 0 0 8 8 8 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKK15039.1 - 4e-07 30.2 0.0 0.00039 20.7 0.0 3.9 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KKK15039.1 - 0.0019 17.2 0.1 0.12 11.3 0.1 2.9 2 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KKK15039.1 - 0.19 11.7 0.1 0.7 9.9 0.0 2.0 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat WXG100 PF06013.12 KKK15053.1 - 0.0056 16.9 4.2 0.02 15.1 4.2 2.0 1 0 0 1 1 1 1 Proteins of 100 residues with WXG FlaC_arch PF05377.11 KKK15053.1 - 0.43 11.0 9.6 0.86 10.0 1.4 3.9 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) MCC-bdg_PDZ PF10506.9 KKK15053.1 - 5.5 7.1 8.2 6.1 6.9 5.9 2.3 2 0 0 2 2 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome RibD_C PF01872.17 KKK15054.1 - 3.6e-34 118.3 0.0 4.3e-34 118.1 0.0 1.1 1 0 0 1 1 1 1 RibD C-terminal domain adh_short PF00106.25 KKK15055.1 - 3.2e-34 118.1 0.1 4.4e-34 117.7 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KKK15055.1 - 2.4e-25 89.5 0.0 3.5e-25 88.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KKK15055.1 - 4.3e-08 33.3 2.3 8.6e-07 29.0 2.4 2.5 1 1 1 2 2 2 1 KR domain UPF0146 PF03686.13 KKK15055.1 - 0.018 14.9 0.0 0.034 14.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0146) Epimerase PF01370.21 KKK15055.1 - 0.035 13.5 0.0 0.057 12.9 0.0 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family B12-binding PF02310.19 KKK15055.1 - 0.11 12.6 0.1 2.5 8.1 0.0 2.6 3 0 0 3 3 3 0 B12 binding domain Zn_clus PF00172.18 KKK15058.1 - 8e-11 41.9 11.8 2e-10 40.6 11.8 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ATG27 PF09451.10 KKK15058.1 - 0.18 11.7 1.5 0.29 10.9 1.5 1.3 1 0 0 1 1 1 0 Autophagy-related protein 27 WD40 PF00400.32 KKK15069.1 - 1.3e-25 89.1 14.8 3.4e-08 34.0 0.9 6.4 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKK15069.1 - 5.6e-19 68.2 1.5 0.00037 20.7 0.8 4.6 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KKK15069.1 - 6.2e-06 26.2 0.0 0.0094 15.8 0.0 2.4 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Lactonase PF10282.9 KKK15069.1 - 9.3e-05 21.8 0.0 0.0017 17.7 0.0 2.6 1 1 1 2 2 2 1 Lactonase, 7-bladed beta-propeller Nup160 PF11715.8 KKK15069.1 - 0.00014 20.7 0.1 0.0053 15.5 0.1 2.1 2 0 0 2 2 2 1 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 KKK15069.1 - 0.00045 18.9 0.0 0.0013 17.4 0.0 1.7 2 1 0 2 2 2 1 Cytochrome D1 heme domain Ge1_WD40 PF16529.5 KKK15069.1 - 0.0047 15.9 1.3 0.82 8.6 0.0 3.3 1 1 3 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 KKK15069.1 - 0.0048 16.3 0.4 1.1 8.5 0.0 3.7 2 2 2 4 4 4 1 Neuroblastoma-amplified sequence, N terminal WD40_like PF17005.5 KKK15069.1 - 0.025 13.9 0.0 3 7.1 0.0 2.8 1 1 2 3 3 3 0 WD40-like domain Coatomer_WDAD PF04053.14 KKK15069.1 - 0.064 12.3 0.0 0.085 11.9 0.0 1.2 1 0 0 1 1 1 0 Coatomer WD associated region Septin PF00735.18 KKK15071.1 - 5.8e-113 376.8 0.2 6.9e-113 376.6 0.2 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 KKK15071.1 - 1.4e-07 31.5 0.0 2.8e-07 30.6 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 KKK15071.1 - 1e-05 25.0 0.0 1.9e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 AIG1 family GTP_EFTU PF00009.27 KKK15071.1 - 8.2e-05 22.2 0.6 0.025 14.1 0.1 2.5 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KKK15071.1 - 9.3e-05 22.4 0.4 0.00085 19.3 0.1 2.2 2 0 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 KKK15071.1 - 0.001 19.2 0.3 1.4 8.9 0.0 2.6 1 1 1 2 2 2 2 Dynamin family AAA_16 PF13191.6 KKK15071.1 - 0.0013 19.2 0.1 0.0054 17.1 0.1 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_7 PF12775.7 KKK15071.1 - 0.0017 17.9 0.1 0.0088 15.6 0.0 2.2 2 0 0 2 2 2 1 P-loop containing dynein motor region NB-ARC PF00931.22 KKK15071.1 - 0.0051 16.0 0.1 0.0089 15.2 0.1 1.3 1 0 0 1 1 1 1 NB-ARC domain ABC_tran PF00005.27 KKK15071.1 - 0.018 15.5 0.3 0.025 15.1 0.3 1.6 1 1 0 1 1 1 0 ABC transporter AAA_22 PF13401.6 KKK15071.1 - 0.02 15.2 0.0 0.038 14.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain Gtr1_RagA PF04670.12 KKK15071.1 - 0.03 13.7 0.1 0.44 9.9 0.0 2.2 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region G-alpha PF00503.20 KKK15071.1 - 0.04 13.1 0.3 0.12 11.5 0.3 1.7 1 1 0 1 1 1 0 G-protein alpha subunit FtsK_SpoIIIE PF01580.18 KKK15071.1 - 0.041 13.2 0.0 0.079 12.3 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family Roc PF08477.13 KKK15071.1 - 0.08 13.2 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Ribosomal_L32p PF01783.23 KKK15072.1 - 1.1e-14 54.4 7.3 1.5e-14 53.9 7.3 1.2 1 0 0 1 1 1 1 Ribosomal L32p protein family zf-ribbon_3 PF13248.6 KKK15072.1 - 0.034 13.6 2.8 0.058 12.8 2.8 1.4 1 0 0 1 1 1 0 zinc-ribbon domain zinc-ribbons_6 PF07191.12 KKK15072.1 - 0.061 13.3 0.9 0.094 12.7 0.9 1.4 1 0 0 1 1 1 0 zinc-ribbons DZR PF12773.7 KKK15072.1 - 0.081 13.0 1.9 0.25 11.4 1.9 1.7 1 1 1 2 2 2 0 Double zinc ribbon Zn-ribbon_8 PF09723.10 KKK15072.1 - 0.17 12.0 4.2 4.9 7.3 0.3 2.2 1 1 1 2 2 2 0 Zinc ribbon domain DUF2293 PF10056.9 KKK15073.1 - 1.4e-29 102.1 0.1 2.8e-29 101.2 0.1 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2293) DEAD PF00270.29 KKK15085.1 - 3e-48 163.9 0.0 3.9e-47 160.3 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KKK15085.1 - 2.3e-25 89.1 0.1 1.3e-24 86.7 0.0 2.3 1 1 1 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KKK15085.1 - 0.00068 19.7 0.0 0.0018 18.3 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 KKK15085.1 - 0.015 15.7 0.0 0.9 9.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF5335 PF17269.2 KKK15085.1 - 0.09 12.6 0.0 0.43 10.4 0.1 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5335) DUF2443 PF10398.9 KKK15085.1 - 0.099 12.7 0.2 0.25 11.4 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2443) POTRA_2 PF08479.11 KKK15085.1 - 0.14 12.0 0.0 0.35 10.7 0.0 1.6 1 0 0 1 1 1 0 POTRA domain, ShlB-type AAA_22 PF13401.6 KKK15085.1 - 0.23 11.7 0.4 18 5.6 0.0 3.2 4 0 0 4 4 4 0 AAA domain DNA_pol_B PF00136.21 KKK15086.1 - 1.2e-116 390.1 0.8 1.7e-116 389.7 0.8 1.2 1 0 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.10 KKK15086.1 - 5.6e-69 231.6 1.5 1e-68 230.7 1.5 1.5 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.19 KKK15086.1 - 4.3e-42 144.5 0.0 9.2e-42 143.4 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.8 KKK15086.1 - 5.6e-24 84.0 6.9 5.6e-24 84.0 6.9 2.6 2 0 0 2 2 2 1 DNA polymerase alpha subunit p180 N terminal DNA_pol_B_2 PF03175.13 KKK15086.1 - 0.031 13.2 0.0 0.063 12.1 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase type B, organellar and viral LRR_4 PF12799.7 KKK15086.1 - 0.061 13.8 0.7 42 4.8 0.0 4.4 4 1 0 4 4 4 0 Leucine Rich repeats (2 copies) Phos_pyr_kin PF08543.12 KKK15087.1 - 8.7e-84 280.7 0.4 1.2e-83 280.3 0.4 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.16 KKK15087.1 - 6.8e-53 179.6 0.1 9.7e-53 179.1 0.1 1.2 1 0 0 1 1 1 1 TENA/THI-4/PQQC family PfkB PF00294.24 KKK15087.1 - 3.1e-05 23.4 0.2 0.019 14.3 0.0 2.2 2 0 0 2 2 2 2 pfkB family carbohydrate kinase HK PF02110.15 KKK15087.1 - 0.00017 21.1 0.5 0.0094 15.4 0.0 2.3 2 0 0 2 2 2 2 Hydroxyethylthiazole kinase family Carb_kinase PF01256.17 KKK15087.1 - 0.0023 17.4 2.7 0.012 15.1 2.7 2.1 1 1 0 1 1 1 1 Carbohydrate kinase HsbA PF12296.8 KKK15088.1 - 2.8e-13 50.4 10.5 2.1e-11 44.3 3.1 2.9 2 1 1 3 3 3 2 Hydrophobic surface binding protein A DUF3500 PF12006.8 KKK15088.1 - 0.074 12.5 0.1 0.089 12.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3500) Rad9 PF04139.13 KKK15089.1 - 5.1e-51 173.5 2.5 6.4e-51 173.2 2.5 1.1 1 0 0 1 1 1 1 Rad9 Rad1 PF02144.16 KKK15089.1 - 1.7e-05 24.0 2.3 0.00026 20.2 1.8 2.3 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 DUF2683 PF10884.8 KKK15089.1 - 0.046 14.0 0.0 14 6.0 0.1 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2683) RCC1 PF00415.18 KKK15090.1 - 1.4e-30 105.7 17.9 4.4e-08 33.6 0.1 8.0 7 2 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KKK15090.1 - 1.1e-20 72.8 18.1 1.7e-07 30.9 0.1 5.5 5 0 0 5 5 5 5 Regulator of chromosome condensation (RCC1) repeat Cupin_1 PF00190.22 KKK15090.1 - 0.13 11.9 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Cupin Sugar_tr PF00083.24 KKK15091.1 - 1.4e-22 80.2 23.2 4.9e-14 52.0 4.9 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter Prenyltrans PF00432.21 KKK15114.1 - 7e-41 137.7 35.1 3.1e-11 42.8 2.6 6.2 6 0 0 6 6 6 6 Prenyltransferase and squalene oxidase repeat dsrm PF00035.26 KKK15115.1 - 0.0002 22.0 0.0 0.00038 21.1 0.0 1.5 1 0 0 1 1 1 1 Double-stranded RNA binding motif DND1_DSRM PF14709.7 KKK15115.1 - 0.063 13.5 0.1 0.12 12.7 0.1 1.5 1 1 0 1 1 1 0 double strand RNA binding domain from DEAD END PROTEIN 1 MCU PF04678.13 KKK15116.1 - 1.2e-25 90.6 0.1 1.2e-25 90.6 0.1 2.0 2 0 0 2 2 2 1 Mitochondrial calcium uniporter Hpt PF01627.23 KKK15117.1 - 7.4e-11 42.2 0.0 1.8e-10 40.9 0.0 1.6 2 0 0 2 2 2 1 Hpt domain PTPLA PF04387.14 KKK15118.1 - 2.4e-56 190.0 2.2 3.7e-56 189.4 2.2 1.3 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA Adaptin_binding PF10199.9 KKK15119.1 - 6.5e-15 55.8 2.1 6.5e-15 55.8 2.1 2.3 2 1 0 2 2 2 1 Alpha and gamma adaptin binding protein p34 Nop16 PF09420.10 KKK15119.1 - 0.0035 17.4 4.2 0.008 16.2 4.2 1.5 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 zf-H2C2_2 PF13465.6 KKK15124.1 - 1.4e-05 25.3 27.8 6.1e-05 23.3 3.3 4.7 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2 PF00096.26 KKK15124.1 - 2.1e-05 24.7 14.0 0.00081 19.7 4.5 3.3 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KKK15124.1 - 0.035 14.9 20.3 0.056 14.3 3.0 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KKK15124.1 - 0.037 14.3 0.2 0.13 12.6 0.2 1.9 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 KKK15124.1 - 0.066 13.8 1.3 0.23 12.1 0.1 2.4 1 1 1 2 2 2 0 FOXP coiled-coil domain zf-C2H2_6 PF13912.6 KKK15124.1 - 0.12 12.4 0.8 9.6 6.3 0.2 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger zf-LYAR PF08790.11 KKK15125.1 - 0.12 12.3 0.3 0.24 11.3 0.3 1.5 1 0 0 1 1 1 0 LYAR-type C2HC zinc finger LSM PF01423.22 KKK15126.1 - 1.3e-14 53.6 0.1 2e-14 53.0 0.1 1.3 1 0 0 1 1 1 1 LSM domain NUC173 PF08161.12 KKK15127.1 - 6.8e-83 277.3 0.3 1.1e-80 270.2 0.1 3.2 3 0 0 3 3 3 1 NUC173 domain Stork_head PF10264.9 KKK15127.1 - 0.003 17.7 0.0 0.012 15.8 0.0 2.0 1 0 0 1 1 1 1 Winged helix Storkhead-box1 domain HEAT PF02985.22 KKK15127.1 - 0.014 15.6 0.8 4 8.0 0.0 3.6 3 0 0 3 3 3 0 HEAT repeat HEAT_2 PF13646.6 KKK15127.1 - 0.044 14.2 0.1 0.65 10.4 0.0 3.0 2 0 0 2 2 2 0 HEAT repeats DUF5071 PF16804.5 KKK15127.1 - 0.13 12.6 0.0 8.5 6.7 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5071) FAM176 PF14851.6 KKK15127.1 - 4.9 6.8 9.7 16 5.1 4.8 2.5 2 0 0 2 2 2 0 FAM176 family DUF3245 PF11595.8 KKK15127.1 - 7.8 7.0 16.3 6.6 7.2 4.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3245) Pkinase PF00069.25 KKK15131.1 - 1.6e-20 73.6 0.0 6.1e-12 45.5 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KKK15131.1 - 1.6e-08 34.1 0.0 6.5e-05 22.3 0.0 2.8 2 1 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.14 KKK15131.1 - 0.0001 21.8 0.0 0.00018 21.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KKK15131.1 - 0.00049 19.5 0.0 0.5 9.6 0.0 3.0 3 0 0 3 3 3 1 Kinase-like APH PF01636.23 KKK15131.1 - 0.0012 18.9 0.0 0.0022 18.0 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Tudor_3 PF18115.1 KKK15140.1 - 1e-06 28.4 0.0 1.8e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain DUF4537 PF15057.6 KKK15140.1 - 0.0084 16.1 0.0 0.014 15.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) LBR_tudor PF09465.10 KKK15140.1 - 0.016 15.0 0.0 0.032 14.0 0.0 1.5 1 0 0 1 1 1 0 Lamin-B receptor of TUDOR domain Fis1_TPR_C PF14853.6 KKK15140.1 - 0.1 12.7 0.2 0.18 11.9 0.2 1.3 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat TP2 PF01254.18 KKK15140.1 - 0.65 10.6 8.7 0.053 14.1 3.3 1.8 2 0 0 2 2 2 0 Nuclear transition protein 2 PAP1 PF08601.10 KKK15141.1 - 1.2e-128 430.0 16.1 1.2e-128 430.0 16.1 2.9 3 0 0 3 3 3 1 Transcription factor PAP1 bZIP_1 PF00170.21 KKK15141.1 - 2.5e-08 33.9 8.7 5.8e-08 32.7 8.7 1.6 1 0 0 1 1 1 1 bZIP transcription factor SHE3 PF17078.5 KKK15141.1 - 0.0044 16.8 1.9 0.0085 15.8 1.9 1.4 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 DUF16 PF01519.16 KKK15141.1 - 0.063 13.8 0.3 0.15 12.6 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function DUF16 bZIP_2 PF07716.15 KKK15141.1 - 0.068 13.3 12.5 0.23 11.6 11.8 2.1 1 1 0 1 1 1 0 Basic region leucine zipper bZIP_Maf PF03131.17 KKK15141.1 - 0.22 12.0 11.4 0.18 12.4 8.7 2.2 2 0 0 2 2 2 0 bZIP Maf transcription factor HAUS-augmin3 PF14932.6 KKK15141.1 - 0.6 9.6 5.0 0.17 11.5 1.8 1.7 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 DUF2514 PF10721.9 KKK15141.1 - 0.62 10.1 4.3 1.3 9.0 4.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) CDC45 PF02724.14 KKK15141.1 - 2.7 6.2 6.9 4.5 5.4 6.9 1.3 1 0 0 1 1 1 0 CDC45-like protein DUF4407 PF14362.6 KKK15141.1 - 2.7 7.2 4.2 4.4 6.6 4.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4965 PF16335.5 KKK15142.1 - 9.8e-68 227.2 0.6 1.5e-67 226.6 0.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4965) DUF5127 PF17168.4 KKK15142.1 - 3e-64 216.9 0.1 4.6e-64 216.3 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) DUF2433 PF10360.9 KKK15142.1 - 2.2e-48 163.4 0.0 6.5e-48 161.9 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2433) DUF1793 PF08760.11 KKK15142.1 - 2.1e-45 155.2 0.0 3.8e-45 154.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) DUF4964 PF16334.5 KKK15142.1 - 5.9e-09 35.4 0.1 1.4e-08 34.2 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4964) Glyco_hydr_116N PF12215.8 KKK15142.1 - 0.00014 21.5 0.1 0.00036 20.1 0.1 1.7 1 0 0 1 1 1 1 beta-glucosidase 2, glycosyl-hydrolase family 116 N-term Metallophos_2 PF12850.7 KKK15142.1 - 0.0027 17.9 0.0 0.0083 16.3 0.0 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 KKK15142.1 - 0.0038 17.7 0.0 0.0087 16.6 0.0 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase zf-RING_2 PF13639.6 KKK15184.1 - 2e-13 50.4 5.7 3.3e-13 49.7 5.7 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KKK15184.1 - 4.3e-10 39.1 2.5 7.8e-10 38.3 2.5 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KKK15184.1 - 8.2e-09 35.2 6.1 1.3e-08 34.5 6.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KKK15184.1 - 1.4e-07 31.3 3.6 2.2e-07 30.6 3.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KKK15184.1 - 1.5e-06 28.4 7.1 4.3e-06 26.9 7.1 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KKK15184.1 - 3.9e-05 23.5 2.5 6.7e-05 22.8 2.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KKK15184.1 - 0.00013 21.8 8.1 0.0013 18.6 7.5 2.4 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 KKK15184.1 - 0.00015 21.5 2.1 0.00025 20.9 2.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KKK15184.1 - 0.00095 19.1 5.0 0.0018 18.3 4.6 1.7 1 1 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 KKK15184.1 - 0.0017 18.4 2.8 0.0035 17.3 2.8 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 KKK15184.1 - 0.0067 16.2 4.1 0.012 15.4 4.1 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING-like PF08746.11 KKK15184.1 - 0.17 12.2 2.0 0.3 11.4 2.0 1.4 1 0 0 1 1 1 0 RING-like domain Zn_ribbon_17 PF17120.5 KKK15184.1 - 0.42 10.3 2.7 0.7 9.6 2.7 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4_4 PF15227.6 KKK15184.1 - 0.48 10.6 5.6 0.95 9.7 5.6 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.8 KKK15184.1 - 1.4 9.2 5.1 9.4 6.5 5.1 2.4 1 1 0 1 1 1 0 FANCL C-terminal domain PHD PF00628.29 KKK15184.1 - 5 7.1 5.0 21 5.1 5.2 2.0 1 1 1 2 2 2 0 PHD-finger AMP-binding PF00501.28 KKK15185.1 - 1.3e-53 182.1 0.0 2e-53 181.5 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme ECH_1 PF00378.20 KKK15185.1 - 5.1e-44 150.5 0.0 8.5e-44 149.7 0.0 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase HMGL-like PF00682.19 KKK15185.1 - 8.9e-43 146.7 0.0 1.3e-42 146.2 0.0 1.3 1 0 0 1 1 1 1 HMGL-like ECH_2 PF16113.5 KKK15185.1 - 5.1e-26 92.0 0.0 9.4e-26 91.1 0.0 1.4 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase AMP-binding_C PF13193.6 KKK15185.1 - 1.5e-05 25.8 0.1 6.6e-05 23.8 0.0 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Fungal_trans PF04082.18 KKK15186.1 - 1.2e-26 93.4 1.7 1.7e-26 92.8 1.7 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK15186.1 - 2.7e-08 33.8 12.1 5.6e-08 32.8 12.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain LysM PF01476.20 KKK15187.1 - 5.2e-05 23.2 0.2 0.00022 21.2 0.0 2.1 2 0 0 2 2 2 1 LysM domain RIFIN PF02009.16 KKK15187.1 - 0.33 10.8 4.3 0.52 10.1 4.3 1.3 1 0 0 1 1 1 0 Rifin SOG2 PF10428.9 KKK15187.1 - 0.57 9.3 20.1 0.73 9.0 20.1 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein GREB1 PF15782.5 KKK15187.1 - 4.5 4.3 10.2 5.8 3.9 10.2 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SAP130_C PF16014.5 KKK15187.1 - 9.7 5.2 17.2 16 4.4 17.2 1.5 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP130 C-terminus bZIP_1 PF00170.21 KKK15188.1 - 0.0047 17.0 0.7 0.01 15.9 0.7 1.5 1 0 0 1 1 1 1 bZIP transcription factor DivIC PF04977.15 KKK15188.1 - 0.11 12.3 1.5 0.2 11.4 1.5 1.3 1 0 0 1 1 1 0 Septum formation initiator Epimerase PF01370.21 KKK15189.1 - 8.1e-15 54.9 0.0 1.7e-14 53.9 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KKK15189.1 - 4.7e-11 42.2 0.0 1.2e-10 40.9 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KKK15189.1 - 5.5e-08 32.9 0.0 1.4e-07 31.6 0.0 1.6 2 0 0 2 2 2 1 NAD(P)H-binding NAD_binding_4 PF07993.12 KKK15189.1 - 1.9e-06 27.2 0.0 0.0023 17.1 0.0 2.3 2 0 0 2 2 2 2 Male sterility protein GDP_Man_Dehyd PF16363.5 KKK15189.1 - 3.1e-06 26.8 0.0 1.1e-05 25.1 0.0 1.9 3 0 0 3 3 3 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 KKK15189.1 - 6.6e-05 22.2 0.0 0.00014 21.1 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.13 KKK15189.1 - 0.0034 17.0 0.0 0.024 14.2 0.0 2.0 2 0 0 2 2 2 1 NmrA-like family adh_short PF00106.25 KKK15189.1 - 0.0048 16.4 0.0 0.023 14.2 0.0 2.1 3 0 0 3 3 3 1 short chain dehydrogenase KR PF08659.10 KKK15189.1 - 0.023 14.6 0.0 5.1 7.0 0.0 2.2 2 0 0 2 2 2 0 KR domain Tautomerase_3 PF14832.6 KKK15190.1 - 2.8e-50 170.1 0.1 3.1e-50 169.9 0.1 1.0 1 0 0 1 1 1 1 Putative oxalocrotonate tautomerase enzyme AA_permease_2 PF13520.6 KKK15191.1 - 1.8e-54 185.2 41.5 2.1e-54 185.0 41.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KKK15191.1 - 2.4e-18 66.0 28.0 2.4e-18 66.0 28.0 2.1 2 0 0 2 2 2 1 Amino acid permease Glyco_hydro_76 PF03663.14 KKK15192.1 - 1e-129 433.2 24.6 8.5e-123 410.5 22.8 2.0 1 1 1 2 2 2 2 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 KKK15192.1 - 0.013 14.6 12.1 0.11 11.5 1.9 2.9 1 1 1 2 2 2 0 Glycosyl Hydrolase Family 88 Peptidase_S10 PF00450.22 KKK15193.1 - 2.1e-94 317.3 0.1 2.7e-94 317.0 0.1 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase YXWGXW PF12779.7 KKK15193.1 - 0.017 15.3 0.8 0.043 14.0 0.8 1.7 1 0 0 1 1 1 0 YXWGXW repeat (2 copies) Glyco_hydro_92 PF07971.12 KKK15194.1 - 4.7e-149 497.2 0.1 5.8e-149 496.9 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 KKK15194.1 - 1.5e-60 205.1 4.2 2.8e-60 204.2 4.2 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain Acyl-CoA_dh_1 PF00441.24 KKK15195.1 - 2.1e-29 102.7 2.8 3.1e-29 102.1 2.8 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KKK15195.1 - 1e-23 84.1 0.0 4.7e-23 82.0 0.0 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KKK15195.1 - 2e-21 76.0 0.1 3.4e-21 75.2 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KKK15195.1 - 7.1e-05 23.1 1.3 0.00011 22.5 1.3 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain ATP-sulfurylase PF01747.17 KKK15195.1 - 0.15 11.5 0.2 0.77 9.2 0.0 2.0 2 0 0 2 2 2 0 ATP-sulfurylase HATPase_c PF02518.26 KKK15196.1 - 2.2e-26 92.5 0.0 5.4e-25 88.1 0.0 2.4 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KKK15196.1 - 4.2e-24 84.9 0.0 1.1e-23 83.6 0.0 1.7 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 KKK15196.1 - 1.4e-17 63.5 0.1 3.3e-17 62.3 0.1 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS PF00989.25 KKK15196.1 - 1.6e-14 53.9 0.0 4.9e-09 36.2 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 KKK15196.1 - 1.1e-12 48.1 0.0 2.3e-10 40.6 0.0 2.5 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.10 KKK15196.1 - 9.7e-10 38.7 0.0 0.00012 22.3 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_3 PF08447.12 KKK15196.1 - 0.066 13.5 0.1 0.15 12.4 0.1 1.6 1 0 0 1 1 1 0 PAS fold Alpha-amylase PF00128.24 KKK15197.1 - 6.8e-66 223.1 0.7 9e-66 222.7 0.7 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain CBM_20 PF00686.19 KKK15197.1 - 9.8e-34 115.1 0.1 2.4e-33 113.9 0.1 1.7 1 0 0 1 1 1 1 Starch binding domain DUF1966 PF09260.11 KKK15197.1 - 3.2e-32 110.7 0.2 6.6e-32 109.7 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) Cu-oxidase_3 PF07732.15 KKK15198.1 - 7.7e-41 138.8 3.4 7.7e-41 138.8 3.4 3.5 3 1 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 KKK15198.1 - 1.2e-39 135.2 13.9 9.1e-38 129.1 3.5 2.9 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.22 KKK15198.1 - 1.9e-39 135.3 0.8 2.2e-36 125.4 0.1 3.0 2 1 1 3 3 3 2 Multicopper oxidase Med12-PQL PF12144.8 KKK15198.1 - 0.09 12.7 0.1 0.18 11.6 0.1 1.4 1 0 0 1 1 1 0 Eukaryotic Mediator 12 catenin-binding domain Carboxyl_trans PF01039.22 KKK15199.1 - 4.1e-103 345.7 0.0 5.2e-103 345.3 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.17 KKK15200.1 - 2e-70 236.6 0.0 3.4e-70 235.8 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 KKK15200.1 - 1.3e-34 119.0 0.4 4.2e-23 82.0 0.0 2.6 2 0 0 2 2 2 2 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 KKK15200.1 - 6.8e-30 103.4 0.0 1.6e-29 102.2 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 KKK15200.1 - 4.6e-12 45.6 2.3 9.3e-12 44.6 2.3 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp PF02222.22 KKK15200.1 - 2.8e-09 36.8 0.0 6.7e-09 35.5 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 KKK15200.1 - 2.5e-08 33.7 0.0 5.5e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.14 KKK15200.1 - 4.8e-05 23.5 0.0 8e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_YheCD PF14398.6 KKK15200.1 - 0.016 14.4 0.0 2.2 7.5 0.0 2.4 2 0 0 2 2 2 0 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 KKK15200.1 - 0.02 14.1 0.0 0.094 12.0 0.0 1.9 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp Biotin_lipoyl_2 PF13533.6 KKK15200.1 - 0.043 13.7 0.0 0.16 11.8 0.0 2.0 2 0 0 2 2 2 0 Biotin-lipoyl like GCV_H PF01597.19 KKK15200.1 - 0.091 12.7 0.1 0.3 11.0 0.2 1.8 2 0 0 2 2 2 0 Glycine cleavage H-protein ATP-grasp_4 PF13535.6 KKK15200.1 - 0.1 12.2 0.0 0.27 10.8 0.0 1.7 1 0 0 1 1 1 0 ATP-grasp domain DUF3182 PF11379.8 KKK15200.1 - 0.12 11.3 0.0 0.23 10.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3182) adh_short PF00106.25 KKK15201.1 - 3.5e-18 65.8 0.3 1e-16 61.0 0.3 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KKK15201.1 - 3e-13 49.9 0.1 8.2e-12 45.2 0.1 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Zn_clus PF00172.18 KKK15202.1 - 3.7e-08 33.3 12.1 6.2e-08 32.6 12.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KKK15202.1 - 0.00053 18.9 0.1 0.11 11.3 0.0 2.6 2 1 0 2 2 2 2 Fungal specific transcription factor domain PHD PF00628.29 KKK15203.1 - 5.3e-08 32.6 9.3 5.3e-08 32.6 9.3 1.6 2 0 0 2 2 2 1 PHD-finger Zf_RING PF16744.5 KKK15203.1 - 0.016 15.3 5.9 0.032 14.3 5.9 1.5 1 0 0 1 1 1 0 KIAA1045 RING finger Shugoshin_N PF07558.11 KKK15203.1 - 0.029 14.2 0.4 0.049 13.5 0.4 1.3 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region DivIC PF04977.15 KKK15203.1 - 0.075 12.8 0.3 0.12 12.2 0.3 1.2 1 0 0 1 1 1 0 Septum formation initiator YabA PF06156.13 KKK15203.1 - 0.08 13.6 0.1 0.13 12.9 0.1 1.3 1 0 0 1 1 1 0 Initiation control protein YabA Cep57_CLD_2 PF14197.6 KKK15203.1 - 0.081 13.0 0.4 0.13 12.3 0.4 1.2 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 CASP_C PF08172.12 KKK15203.1 - 0.12 11.7 0.1 0.25 10.7 0.1 1.4 1 0 0 1 1 1 0 CASP C terminal zf-HC5HC2H PF13771.6 KKK15203.1 - 0.17 12.1 4.1 0.36 11.1 4.1 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain zf-RING_2 PF13639.6 KKK15203.1 - 3.3 8.1 15.5 0.39 11.1 11.3 1.7 2 0 0 2 2 2 0 Ring finger domain SnoaL PF07366.12 KKK15204.1 - 0.00011 22.0 0.0 0.00019 21.3 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 KKK15204.1 - 0.00047 20.8 0.0 0.00093 19.8 0.0 1.5 1 0 0 1 1 1 1 SnoaL-like domain Med4 PF10018.9 KKK15205.1 - 6.1e-58 195.7 0.3 9.2e-58 195.1 0.0 1.4 2 0 0 2 2 2 1 Vitamin-D-receptor interacting Mediator subunit 4 DUF2193 PF09959.9 KKK15205.1 - 0.035 12.6 0.1 0.045 12.2 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2193) Dynamin_N PF00350.23 KKK15206.1 - 3.8e-36 124.7 0.0 6e-36 124.0 0.0 1.3 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 KKK15206.1 - 1.3e-25 90.2 0.1 1.9e-25 89.7 0.1 1.2 1 0 0 1 1 1 1 Dynamin central region MMR_HSR1 PF01926.23 KKK15206.1 - 9.1e-06 25.7 0.0 2.9e-05 24.1 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_15 PF13175.6 KKK15206.1 - 0.05 13.3 0.1 0.15 11.7 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain AAA_21 PF13304.6 KKK15206.1 - 0.078 12.8 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KKK15206.1 - 0.084 13.4 0.0 0.9 10.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 KKK15206.1 - 0.099 12.4 0.0 0.23 11.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain MS_channel PF00924.18 KKK15222.1 - 4.8e-21 75.3 1.2 8e-21 74.5 1.2 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.32 KKK15222.1 - 0.00012 21.4 0.4 0.00028 20.2 0.4 1.7 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 KKK15222.1 - 0.00051 19.8 0.0 0.0015 18.3 0.0 1.8 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 KKK15222.1 - 0.0069 16.8 0.1 0.022 15.2 0.1 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 KKK15222.1 - 0.043 13.3 0.1 0.13 11.8 0.1 1.8 1 0 0 1 1 1 0 EF hand LRR19-TM PF15176.6 KKK15222.1 - 0.074 13.1 0.0 0.35 10.9 0.0 2.1 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain CDT1_C PF16679.5 KKK15222.1 - 0.73 10.3 0.0 0.73 10.3 0.0 2.2 3 0 0 3 3 3 0 DNA replication factor Cdt1 C-terminal domain YjbE PF11106.8 KKK15222.1 - 0.82 9.9 3.9 2.6 8.3 3.9 1.8 1 0 0 1 1 1 0 Exopolysaccharide production protein YjbE Mgm101p PF06420.12 KKK15223.1 - 2.1e-85 284.4 0.0 2.7e-85 284.1 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 Zn_clus PF00172.18 KKK15224.1 - 6.4e-08 32.6 11.8 1.2e-07 31.7 11.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SCNM1_acidic PF15805.5 KKK15261.1 - 0.04 13.6 0.5 0.086 12.6 0.5 1.4 1 0 0 1 1 1 0 Acidic C-terminal region of sodium channel modifier 1 SCNM1 F-box-like PF12937.7 KKK15261.1 - 0.34 10.8 6.5 0.054 13.4 1.4 2.5 2 1 0 2 2 2 0 F-box-like DIM1 PF02966.16 KKK15262.1 - 9e-69 229.4 0.3 1e-68 229.2 0.3 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.20 KKK15262.1 - 0.14 12.1 0.0 0.19 11.7 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin Translin PF01997.16 KKK15263.1 - 2.3e-49 168.2 0.0 2.7e-49 168.0 0.0 1.0 1 0 0 1 1 1 1 Translin family Rx_N PF18052.1 KKK15263.1 - 0.049 13.9 1.6 4.5 7.6 1.0 3.2 2 1 0 2 2 2 0 Rx N-terminal domain GSHPx PF00255.19 KKK15264.1 - 4.8e-39 132.3 0.0 6.4e-39 131.9 0.0 1.2 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 KKK15264.1 - 0.0077 16.1 0.0 0.018 15.0 0.0 1.8 1 1 0 1 1 1 1 AhpC/TSA family Pcc1 PF09341.10 KKK15265.1 - 1.2e-31 108.6 0.1 1.5e-31 108.4 0.1 1.1 1 0 0 1 1 1 1 Transcription factor Pcc1 DUF5405 PF17399.2 KKK15266.1 - 0.31 11.3 2.5 12 6.2 0.1 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF5405) DSPn PF14671.6 KKK15267.1 - 4.5e-43 147.1 0.0 5.1e-41 140.4 0.0 2.7 2 1 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 KKK15267.1 - 4.5e-16 58.9 0.1 1.5e-15 57.2 0.0 1.9 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KKK15267.1 - 8.7e-06 25.5 0.0 1.5e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.13 KKK15267.1 - 0.028 14.0 0.0 0.052 13.1 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family Fungal_trans_2 PF11951.8 KKK15268.1 - 1.9e-09 36.8 0.4 3.2e-09 36.1 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK15268.1 - 2e-07 31.0 8.7 3.6e-07 30.2 8.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KKK15270.1 - 9.4e-30 103.5 0.0 1.6e-29 102.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK15270.1 - 2.9e-11 43.3 12.6 4.9e-11 42.6 12.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4446 PF14584.6 KKK15270.1 - 0.12 12.3 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) Beta_elim_lyase PF01212.21 KKK15271.1 - 4.8e-35 121.2 0.0 6.6e-35 120.8 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Fungal_trans PF04082.18 KKK15271.1 - 1.2e-06 27.8 0.1 1.9e-06 27.1 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Aminotran_5 PF00266.19 KKK15271.1 - 0.00012 21.2 0.0 0.00019 20.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 KKK15271.1 - 0.00059 19.1 0.0 0.00092 18.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Zn_clus PF00172.18 KKK15271.1 - 0.015 15.4 3.9 0.032 14.4 3.9 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Met_gamma_lyase PF06838.11 KKK15271.1 - 0.14 10.6 0.0 0.21 10.1 0.0 1.1 1 0 0 1 1 1 0 Methionine gamma-lyase PHD PF00628.29 KKK15272.1 - 7.7e-11 41.7 7.5 1.8e-10 40.6 7.5 1.7 1 0 0 1 1 1 1 PHD-finger Nucleo_P87 PF07267.11 KKK15272.1 - 4.1 6.1 4.9 6.7 5.4 4.9 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Fungal_trans_2 PF11951.8 KKK15273.1 - 6.1e-06 25.3 0.0 4.5e-05 22.4 0.0 2.2 2 0 0 2 2 2 1 Fungal specific transcription factor domain Amino_oxidase PF01593.24 KKK15274.1 - 3.5e-42 145.3 3.9 2.3e-18 66.7 0.0 3.0 2 1 0 3 3 3 3 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KKK15274.1 - 1.9e-14 53.6 0.5 4.3e-14 52.5 0.5 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KKK15274.1 - 8e-07 29.2 0.2 0.0023 18.0 0.3 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox PF00070.27 KKK15274.1 - 2.4e-06 28.0 0.1 4.6e-06 27.1 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KKK15274.1 - 6.5e-06 25.6 1.2 1.5e-05 24.4 1.2 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KKK15274.1 - 3.9e-05 22.5 0.2 3.9e-05 22.5 0.2 1.5 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.24 KKK15274.1 - 9e-05 22.2 2.0 0.00067 19.3 2.0 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 KKK15274.1 - 0.00034 20.0 0.1 0.00054 19.3 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 KKK15274.1 - 0.00049 19.3 1.0 0.00072 18.8 1.0 1.2 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 KKK15274.1 - 0.0027 17.0 0.1 0.0048 16.2 0.1 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.19 KKK15274.1 - 0.0034 16.7 0.1 0.0051 16.1 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 KKK15274.1 - 0.0045 16.1 0.5 0.007 15.5 0.5 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 KKK15274.1 - 0.0074 15.7 0.9 0.011 15.1 0.9 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase 3HCDH_N PF02737.18 KKK15274.1 - 0.029 14.3 0.7 0.042 13.7 0.2 1.5 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 KKK15274.1 - 0.19 12.2 0.1 0.38 11.2 0.1 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding FMO-like PF00743.19 KKK15274.1 - 0.21 10.0 0.0 0.35 9.2 0.0 1.3 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KKK15274.1 - 0.48 9.6 1.8 0.55 9.4 0.3 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase PhyH PF05721.13 KKK15275.1 - 1.6e-18 67.8 0.0 2.4e-18 67.2 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF2235 PF09994.9 KKK15276.1 - 3.1e-101 338.5 0.2 4.2e-101 338.1 0.2 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Sugar_tr PF00083.24 KKK15278.1 - 5.1e-100 335.5 25.6 5.7e-100 335.3 25.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKK15278.1 - 2.1e-31 109.1 47.8 4.6e-27 94.9 25.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KKK15278.1 - 0.00056 18.5 1.0 0.00098 17.7 1.0 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF3180 PF11377.8 KKK15278.1 - 0.15 12.2 5.0 0.47 10.6 1.1 2.8 1 1 0 2 2 2 0 Protein of unknown function (DUF3180) Adeno_E3_CR2 PF02439.15 KKK15279.1 - 0.018 14.8 0.1 0.025 14.3 0.1 1.2 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Homeodomain PF00046.29 KKK15280.1 - 6.2e-15 54.8 3.3 1.3e-14 53.7 3.3 1.6 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KKK15280.1 - 0.13 12.2 0.4 0.3 11.0 0.4 1.6 1 0 0 1 1 1 0 Homeobox KN domain Cation_efflux PF01545.21 KKK15281.1 - 6.9e-23 81.4 13.0 8.7e-23 81.1 13.0 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 KKK15281.1 - 2.3e-06 27.6 0.0 4.6e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter An_peroxidase PF03098.15 KKK15282.1 - 1.9e-37 129.1 0.0 2.5e-24 85.7 0.0 3.2 1 1 1 2 2 2 2 Animal haem peroxidase Pkinase PF00069.25 KKK15317.1 - 1.3e-62 211.6 0.0 1.6e-62 211.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK15317.1 - 1.8e-30 106.1 0.0 2.6e-30 105.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KKK15317.1 - 0.002 17.2 0.0 0.0026 16.8 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain zf-UBR PF02207.20 KKK15318.1 - 7e-14 51.7 4.6 7e-14 51.7 4.6 3.3 3 0 0 3 3 3 1 Putative zinc finger in N-recognin (UBR box) MCM_bind PF09739.9 KKK15318.1 - 0.38 9.1 3.0 0.54 8.6 3.0 1.2 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor DUF3246 PF11596.8 KKK15318.1 - 0.4 10.1 7.4 0.17 11.3 2.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3246) Nop14 PF04147.12 KKK15318.1 - 0.46 8.6 8.4 0.71 8.0 8.4 1.3 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 KKK15318.1 - 5.8 5.1 8.1 11 4.2 8.1 1.4 1 0 0 1 1 1 0 CDC45-like protein Pal1 PF08316.11 KKK15320.1 - 4.4e-46 157.0 0.6 1.2e-45 155.7 0.6 1.8 1 0 0 1 1 1 1 Pal1 cell morphology protein CDC45 PF02724.14 KKK15320.1 - 3.3 5.9 6.3 4.4 5.5 6.3 1.1 1 0 0 1 1 1 0 CDC45-like protein MCM PF00493.23 KKK15321.1 - 8.6e-102 339.0 0.0 1.3e-101 338.4 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KKK15321.1 - 4.1e-39 133.3 0.4 7.6e-39 132.4 0.4 1.4 1 0 0 1 1 1 1 MCM OB domain MCM2_N PF12619.8 KKK15321.1 - 2.2e-25 89.7 41.7 2.2e-25 89.7 41.7 2.3 3 0 0 3 3 2 1 Mini-chromosome maintenance protein 2 MCM_lid PF17855.1 KKK15321.1 - 1.8e-24 85.9 1.4 3.1e-24 85.2 0.3 2.1 2 0 0 2 2 1 1 MCM AAA-lid domain MCM_N PF14551.6 KKK15321.1 - 3.7e-13 50.0 0.0 1.1e-12 48.5 0.0 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 KKK15321.1 - 3.8e-09 36.2 0.1 9.3e-07 28.4 0.0 2.5 1 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KKK15321.1 - 3.7e-06 27.0 0.0 7.7e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 KKK15321.1 - 0.00097 19.0 0.0 0.0045 16.8 0.0 2.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KKK15321.1 - 0.0034 17.1 0.2 0.024 14.3 0.2 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain Zn_ribbon_2 PF12674.7 KKK15321.1 - 0.07 13.8 0.7 0.18 12.5 0.7 1.7 1 0 0 1 1 1 0 Putative zinc ribbon domain zinc_ribbon_10 PF10058.9 KKK15321.1 - 0.24 11.1 1.3 0.49 10.2 1.3 1.5 1 0 0 1 1 1 0 Predicted integral membrane zinc-ribbon metal-binding protein Med31 PF05669.12 KKK15322.1 - 1.7e-31 108.1 0.0 2.1e-31 107.7 0.0 1.1 1 0 0 1 1 1 1 SOH1 Alk_phosphatase PF00245.20 KKK15323.1 - 4.9e-61 206.9 0.1 1.8e-60 205.1 0.1 1.8 1 1 0 1 1 1 1 Alkaline phosphatase Sulfatase PF00884.23 KKK15323.1 - 1.3e-06 28.1 0.5 4.4e-06 26.3 0.5 2.0 2 1 0 2 2 2 1 Sulfatase Phosphodiest PF01663.22 KKK15323.1 - 5.5e-05 22.9 0.1 0.0001 22.0 0.1 1.5 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 KKK15323.1 - 0.0026 16.4 0.1 0.0046 15.6 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF229) HHH_3 PF12836.7 KKK15323.1 - 0.018 15.3 0.0 0.04 14.2 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix motif Metalloenzyme PF01676.18 KKK15323.1 - 0.029 13.7 0.0 0.053 12.9 0.0 1.4 1 0 0 1 1 1 0 Metalloenzyme superfamily Palm_thioest PF02089.15 KKK15325.1 - 1.4e-84 283.7 0.0 1.7e-84 283.5 0.0 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF915 PF06028.11 KKK15325.1 - 0.0069 15.8 0.0 0.012 14.9 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_1 PF00561.20 KKK15325.1 - 0.022 14.4 0.0 0.044 13.4 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold RNA_pol_Rpb4 PF03874.16 KKK15345.1 - 8.9e-26 90.6 2.7 1.2e-25 90.2 2.7 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb4 Cut8 PF08559.10 KKK15345.1 - 0.003 17.2 0.3 0.0036 16.9 0.3 1.2 1 0 0 1 1 1 1 Cut8, nuclear proteasome tether protein Met_10 PF02475.16 KKK15346.1 - 1.4e-65 220.8 0.0 2e-65 220.3 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Sugar_tr PF00083.24 KKK15347.1 - 6e-77 259.4 22.4 8e-68 229.3 9.7 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KKK15347.1 - 3.2e-22 79.0 20.1 9.1e-22 77.5 20.0 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Fungal_trans PF04082.18 KKK15348.1 - 6.8e-17 61.4 0.0 1.3e-16 60.5 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK15348.1 - 0.00092 19.3 5.9 0.0017 18.4 5.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-GRF PF06839.12 KKK15349.1 - 5.3e-08 32.8 5.2 1.1e-07 31.8 5.2 1.5 1 0 0 1 1 1 1 GRF zinc finger DUF5583 PF17821.1 KKK15349.1 - 0.00056 19.9 0.6 0.00056 19.9 0.6 1.6 2 0 0 2 2 2 1 Family of unknown function (DUF5583) SecD-TM1 PF13721.6 KKK15349.1 - 0.086 13.3 0.1 0.15 12.6 0.1 1.2 1 0 0 1 1 1 0 SecD export protein N-terminal TM region DPPIV_N PF00930.21 KKK15350.1 - 1.3e-117 392.5 0.0 1.7e-117 392.2 0.0 1.1 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 KKK15350.1 - 2.8e-55 187.1 3.1 4.2e-55 186.5 3.1 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KKK15350.1 - 7.8e-05 22.1 0.4 0.05 12.9 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Esterase PF00756.20 KKK15350.1 - 0.00016 21.4 0.2 0.00043 20.0 0.2 1.6 1 1 0 1 1 1 1 Putative esterase Peptidase_S15 PF02129.18 KKK15350.1 - 0.00049 19.8 3.5 0.0032 17.1 2.4 2.2 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) PAF-AH_p_II PF03403.13 KKK15350.1 - 0.00088 17.9 0.0 0.32 9.5 0.0 2.2 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_1 PF00561.20 KKK15350.1 - 0.003 17.3 0.7 0.02 14.5 0.1 2.2 1 1 1 2 2 2 1 alpha/beta hydrolase fold DLH PF01738.18 KKK15350.1 - 0.036 13.6 0.0 0.11 12.0 0.0 1.7 1 1 0 1 1 1 0 Dienelactone hydrolase family AXE1 PF05448.12 KKK15350.1 - 0.14 10.8 0.3 0.43 9.2 0.1 1.9 2 1 0 2 2 2 0 Acetyl xylan esterase (AXE1) DUF3818 PF12825.7 KKK15351.1 - 2e-131 438.1 3.5 3.5e-131 437.3 3.5 1.4 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.7 KKK15351.1 - 1.8e-39 134.7 0.4 3.6e-39 133.7 0.4 1.5 1 0 0 1 1 1 1 PX-associated PX PF00787.24 KKK15351.1 - 1.1e-13 51.1 0.5 4.8e-13 49.1 0.0 2.3 2 1 0 2 2 2 1 PX domain DUF2373 PF10180.9 KKK15351.1 - 0.14 12.1 1.0 0.36 10.7 1.0 1.6 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2373) Glyco_hydro_114 PF03537.13 KKK15352.1 - 7.1e-84 280.7 0.6 8.6e-84 280.5 0.6 1.1 1 0 0 1 1 1 1 Glycoside-hydrolase family GH114 Glycos_transf_1 PF00534.20 KKK15353.1 - 9.8e-12 44.7 0.0 2.6e-11 43.3 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KKK15353.1 - 1.9e-11 44.6 0.0 4.1e-11 43.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 DUF3492 PF11997.8 KKK15353.1 - 0.0066 16.2 0.0 0.02 14.6 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3492) GST_N_3 PF13417.6 KKK15356.1 - 2e-07 31.3 0.1 6.5e-07 29.7 0.1 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KKK15356.1 - 2.6e-05 24.2 0.0 4.5e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KKK15356.1 - 0.0032 17.8 0.0 0.007 16.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_5 PF16865.5 KKK15356.1 - 0.12 13.0 0.0 0.19 12.3 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain PI-PLC-X PF00388.19 KKK15357.1 - 4.8e-61 204.6 0.0 7.9e-61 203.9 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 KKK15357.1 - 3.1e-40 137.1 0.1 6.4e-40 136.1 0.1 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain GDP_Man_Dehyd PF16363.5 KKK15358.1 - 1.7e-37 129.6 0.0 9.2e-37 127.2 0.0 2.0 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KKK15358.1 - 7e-36 123.9 0.0 7.1e-35 120.6 0.0 2.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KKK15358.1 - 1.9e-08 33.8 0.0 5.5e-07 29.0 0.0 2.4 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 KKK15358.1 - 3.7e-06 26.3 0.0 4.5e-05 22.8 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.19 KKK15358.1 - 1.9e-05 23.9 0.0 0.00016 20.7 0.0 2.3 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.10 KKK15358.1 - 0.00084 19.3 0.0 0.0015 18.4 0.0 1.4 1 0 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.17 KKK15358.1 - 0.0051 15.9 0.0 0.055 12.6 0.0 2.4 2 1 0 2 2 2 1 RmlD substrate binding domain adh_short PF00106.25 KKK15358.1 - 0.047 13.1 0.0 0.085 12.3 0.0 1.5 1 0 0 1 1 1 0 short chain dehydrogenase Ribosomal_L37 PF08561.10 KKK15359.1 - 4.8e-44 149.7 0.7 6.2e-44 149.4 0.7 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L37 Spherulin4 PF12138.8 KKK15360.1 - 1e-71 241.4 0.1 1.2e-71 241.2 0.1 1.0 1 0 0 1 1 1 1 Spherulation-specific family 4 Fungal_trans_2 PF11951.8 KKK15361.1 - 7.9e-14 51.3 7.8 5.2e-13 48.6 7.8 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans PF04082.18 KKK15361.1 - 0.067 12.2 2.1 0.097 11.7 0.2 1.9 2 0 0 2 2 2 0 Fungal specific transcription factor domain BNR PF02012.20 KKK15376.1 - 0.059 13.4 0.1 0.49 10.6 0.1 2.7 1 0 0 1 1 1 0 BNR/Asp-box repeat AAA PF00004.29 KKK15377.1 - 5.3e-41 140.1 0.0 2e-37 128.6 0.0 3.0 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KKK15377.1 - 1.8e-10 40.4 0.4 5.5e-10 38.9 0.0 2.1 2 0 0 2 2 2 1 AAA+ lid domain AAA_16 PF13191.6 KKK15377.1 - 2.2e-05 24.9 0.4 0.0019 18.6 0.1 3.5 2 1 0 3 3 3 1 AAA ATPase domain AAA_33 PF13671.6 KKK15377.1 - 2.3e-05 24.6 0.1 0.0037 17.4 0.0 3.0 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.12 KKK15377.1 - 5.1e-05 23.1 0.0 0.00017 21.3 0.0 1.9 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KKK15377.1 - 0.00024 21.4 0.2 0.029 14.6 0.1 3.1 1 1 1 2 2 2 1 AAA domain TIP49 PF06068.13 KKK15377.1 - 0.00031 20.1 0.0 0.0007 18.9 0.0 1.6 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_5 PF07728.14 KKK15377.1 - 0.0012 18.8 0.0 0.0032 17.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.6 KKK15377.1 - 0.006 17.0 2.3 0.12 12.8 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_28 PF13521.6 KKK15377.1 - 0.0075 16.5 0.0 0.043 14.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 KKK15377.1 - 0.0082 15.9 0.0 0.015 15.0 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.6 KKK15377.1 - 0.017 15.2 0.0 0.084 12.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 KKK15377.1 - 0.019 14.3 0.0 0.045 13.1 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_2 PF07724.14 KKK15377.1 - 0.028 14.6 0.0 0.53 10.4 0.0 2.9 3 1 0 3 3 3 0 AAA domain (Cdc48 subfamily) RNA_helicase PF00910.22 KKK15377.1 - 0.028 14.8 0.0 0.082 13.3 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.6 KKK15377.1 - 0.051 14.1 0.0 0.14 12.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KKK15377.1 - 0.075 12.8 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain IPT PF01745.16 KKK15377.1 - 0.098 12.0 0.1 0.54 9.6 0.0 2.0 2 0 0 2 2 2 0 Isopentenyl transferase TsaE PF02367.17 KKK15377.1 - 0.12 12.4 0.1 0.35 10.9 0.0 1.8 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF4050 PF13259.6 KKK15378.1 - 4e-50 170.7 24.8 3.1e-49 167.8 24.8 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF4050) SMBP PF16785.5 KKK15378.1 - 0.0012 19.0 1.5 0.0025 18.0 1.2 1.6 2 0 0 2 2 2 1 Small metal-binding protein Mus7 PF09462.10 KKK15379.1 - 2.3e-227 756.8 0.0 3.3e-227 756.2 0.0 1.2 1 0 0 1 1 1 1 Mus7/MMS22 family PAPA-1 PF04795.12 KKK15380.1 - 1.4e-32 112.3 6.8 1.4e-32 112.3 6.8 3.3 2 1 0 2 2 2 1 PAPA-1-like conserved region Pex14_N PF04695.13 KKK15381.1 - 4.6e-36 124.9 0.0 4.6e-36 124.9 0.0 2.6 3 0 0 3 3 3 2 Peroxisomal membrane anchor protein (Pex14p) conserved region Tmemb_cc2 PF10267.9 KKK15381.1 - 0.16 11.1 0.3 0.46 9.6 0.0 1.8 2 0 0 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein Aldolase_II PF00596.21 KKK15382.1 - 8.1e-07 29.2 0.0 1.2e-06 28.6 0.0 1.3 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain DER1 PF04511.15 KKK15408.1 - 7.7e-52 176.0 5.5 8.9e-52 175.8 5.5 1.0 1 0 0 1 1 1 1 Der1-like family Histone PF00125.24 KKK15409.1 - 5.3e-42 143.3 0.0 6.4e-42 143.0 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 KKK15409.1 - 0.00048 20.2 0.0 0.00079 19.5 0.0 1.3 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 KKK15409.1 - 0.002 18.5 0.1 0.0027 18.0 0.1 1.2 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 KKK15409.1 - 0.055 13.8 0.4 0.11 12.8 0.4 1.4 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 KKK15409.1 - 0.11 12.6 0.0 0.15 12.2 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit LamB_YcsF PF03746.16 KKK15429.1 - 1.9e-16 60.5 0.0 2.1e-16 60.3 0.0 1.0 1 0 0 1 1 1 1 LamB/YcsF family CT_A_B PF02626.15 KKK15430.1 - 4e-74 249.6 0.0 5.8e-74 249.1 0.0 1.2 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain A and B CPSase_L_D2 PF02786.17 KKK15430.1 - 6.7e-54 182.6 0.0 1.2e-53 181.8 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 KKK15430.1 - 2e-39 134.5 0.0 9.5e-39 132.4 0.0 2.0 2 0 0 2 2 2 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 KKK15430.1 - 8.1e-34 116.0 0.0 1.3e-33 115.3 0.0 1.4 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 KKK15430.1 - 5.4e-10 39.0 0.5 2.6e-09 36.8 0.3 2.2 2 0 0 2 2 2 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 KKK15430.1 - 9e-07 28.6 0.0 1.7e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_5 PF13549.6 KKK15430.1 - 0.019 14.4 0.0 0.04 13.4 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain ATP-grasp PF02222.22 KKK15430.1 - 0.049 13.2 0.0 0.079 12.5 0.0 1.3 1 0 0 1 1 1 0 ATP-grasp domain UQ_con PF00179.26 KKK15431.1 - 8.2e-11 41.7 0.1 1.5e-10 40.9 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KKK15431.1 - 0.05 13.9 0.1 0.1 12.9 0.1 1.4 1 0 0 1 1 1 0 RWD domain Glycos_transf_4 PF00953.21 KKK15431.1 - 0.12 12.4 0.1 0.19 11.7 0.1 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 4 Homeobox_KN PF05920.11 KKK15432.1 - 9.4e-17 60.6 1.2 9.4e-17 60.6 1.2 2.0 2 0 0 2 2 2 1 Homeobox KN domain Homeodomain PF00046.29 KKK15432.1 - 0.00015 21.5 0.5 0.00035 20.3 0.5 1.6 1 0 0 1 1 1 1 Homeodomain HTH_Tnp_Tc5 PF03221.16 KKK15432.1 - 0.0022 18.0 0.0 0.0054 16.7 0.0 1.7 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain zf-C2H2_4 PF13894.6 KKK15432.1 - 0.005 17.6 1.3 0.005 17.6 1.3 4.9 5 0 0 5 5 5 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KKK15432.1 - 0.021 15.3 17.3 2.5 8.7 1.3 4.3 4 0 0 4 4 4 0 Zinc finger, C2H2 type Cupin_8 PF13621.6 KKK15433.1 - 9.4e-33 114.0 0.1 1.7e-32 113.2 0.1 1.4 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 KKK15433.1 - 2e-07 30.8 0.0 0.0018 17.8 0.0 2.3 2 0 0 2 2 2 2 Cupin superfamily protein JmjC PF02373.22 KKK15433.1 - 0.0011 19.4 0.0 0.0023 18.3 0.0 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_2 PF07883.11 KKK15433.1 - 0.096 12.4 0.0 0.25 11.1 0.0 1.6 1 0 0 1 1 1 0 Cupin domain GTP1_OBG PF01018.22 KKK15434.1 - 8.5e-41 139.1 3.2 2.8e-30 104.9 4.4 2.2 2 0 0 2 2 2 2 GTP1/OBG MMR_HSR1 PF01926.23 KKK15434.1 - 6.8e-24 84.1 0.0 2.1e-23 82.6 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KKK15434.1 - 1.6e-08 34.3 0.1 3.9e-08 33.0 0.1 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B MeaB PF03308.16 KKK15434.1 - 7.5e-05 21.8 0.0 0.11 11.5 0.0 2.2 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB ABC_tran PF00005.27 KKK15434.1 - 0.02 15.4 1.7 0.053 14.0 0.0 2.1 2 0 0 2 2 2 0 ABC transporter GTP_EFTU PF00009.27 KKK15434.1 - 0.021 14.4 0.0 6.2 6.3 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Ploopntkinase3 PF18751.1 KKK15434.1 - 0.12 12.2 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 Dynamin_N PF00350.23 KKK15434.1 - 0.13 12.3 0.0 2.3 8.2 0.1 2.2 1 1 0 2 2 2 0 Dynamin family 2OG-FeII_Oxy_2 PF13532.6 KKK15435.1 - 1.3e-36 126.6 0.0 1.9e-36 126.1 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily zf-GRF PF06839.12 KKK15435.1 - 0.00013 22.0 6.1 0.00023 21.2 6.1 1.4 1 0 0 1 1 1 1 GRF zinc finger IMS PF00817.20 KKK15436.1 - 5.9e-33 114.0 0.0 2e-17 63.6 0.0 2.3 1 1 1 2 2 2 2 impB/mucB/samB family zf_UBZ PF18439.1 KKK15436.1 - 4.5e-14 51.7 1.1 9.3e-14 50.7 1.1 1.6 1 0 0 1 1 1 1 Ubiquitin-Binding Zinc Finger IMS_C PF11799.8 KKK15436.1 - 3.7e-12 47.0 0.0 7.7e-12 45.9 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 KKK15436.1 - 0.024 14.9 0.0 0.05 13.9 0.0 1.6 1 0 0 1 1 1 0 IMS family HHH motif DUF765 PF05570.11 KKK15436.1 - 0.08 13.1 1.5 0.14 12.4 0.1 2.0 2 0 0 2 2 2 0 Circovirus protein of unknown function (DUF765) GREB1 PF15782.5 KKK15437.1 - 0.34 8.0 9.4 0.46 7.5 9.4 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Chorion_2 PF03964.15 KKK15437.1 - 1 10.2 12.0 0.23 12.3 3.6 2.9 2 0 0 2 2 2 0 Chorion family 2 WSC PF01822.19 KKK15438.1 - 3.1e-06 27.3 7.7 3.1e-06 27.3 7.7 3.3 2 1 1 3 3 3 1 WSC domain Podoplanin PF05808.11 KKK15438.1 - 4.3e-05 23.7 8.8 9e-05 22.6 8.8 1.5 1 0 0 1 1 1 1 Podoplanin TrbL PF04610.14 KKK15438.1 - 0.0041 16.9 2.0 0.0041 16.9 2.0 1.7 2 0 0 2 2 2 1 TrbL/VirB6 plasmid conjugal transfer protein DUF4536 PF15055.6 KKK15438.1 - 0.018 15.3 1.8 0.022 15.0 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4536) Trp_oprn_chp PF09534.10 KKK15438.1 - 0.024 14.5 5.7 0.061 13.1 5.7 1.8 1 1 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) AJAP1_PANP_C PF15298.6 KKK15438.1 - 0.23 11.7 14.0 0.19 11.9 12.0 1.9 1 1 0 1 1 1 0 AJAP1/PANP C-terminus Phage_HK97_TLTM PF06120.11 KKK15438.1 - 0.9 8.7 2.9 1.5 7.9 2.3 1.7 1 1 1 2 2 2 0 Tail length tape measure protein DUF4690 PF15756.5 KKK15438.1 - 4.5 7.9 16.7 43 4.8 16.7 2.4 1 1 0 1 1 1 0 Small Novel Rich in Cartilage Herpes_pp85 PF04637.12 KKK15438.1 - 9.1 4.6 10.2 14 3.9 10.2 1.2 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) DUF3445 PF11927.8 KKK15439.1 - 9.7e-78 260.9 0.0 1.3e-77 260.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Pkinase PF00069.25 KKK15440.1 - 0.0013 18.2 0.0 0.0016 17.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK15440.1 - 0.077 12.3 0.0 0.092 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein tyrosine kinase WD40 PF00400.32 KKK15441.1 - 3.2e-17 62.6 1.8 0.028 15.3 0.0 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKK15441.1 - 7.3e-06 26.2 0.0 19 5.7 0.0 5.0 2 2 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain PALB2_WD40 PF16756.5 KKK15441.1 - 0.007 15.3 0.0 0.019 13.9 0.0 1.6 2 0 0 2 2 2 1 Partner and localizer of BRCA2 WD40 domain Fungal_trans PF04082.18 KKK15442.1 - 1.5e-18 66.8 0.2 1.5e-18 66.8 0.2 2.2 3 0 0 3 3 3 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 KKK15442.1 - 2.2e-06 27.8 10.2 0.00035 20.9 4.0 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KKK15442.1 - 6.7e-05 23.1 2.1 6.7e-05 23.1 2.1 2.5 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KKK15442.1 - 0.00018 22.1 8.3 0.0057 17.4 2.4 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KKK15442.1 - 0.16 12.3 0.3 0.31 11.4 0.3 1.5 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-BED PF02892.15 KKK15442.1 - 1.8 8.6 4.3 1.8 8.7 2.2 2.0 1 1 1 2 2 2 0 BED zinc finger zf-C2H2_11 PF16622.5 KKK15442.1 - 2.4 8.0 9.4 3.5 7.5 0.5 2.6 2 0 0 2 2 2 0 zinc-finger C2H2-type AAA_12 PF13087.6 KKK15443.1 - 1.6e-36 125.9 0.0 2.6e-36 125.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KKK15443.1 - 1.4e-22 80.8 1.6 1.3e-21 77.5 0.1 2.4 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KKK15443.1 - 1.7e-07 31.6 0.0 1.3e-06 28.9 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KKK15443.1 - 6.3e-07 29.3 0.1 0.00012 21.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 KKK15443.1 - 4.7e-05 23.2 0.0 0.022 14.5 0.0 3.3 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase DEAD PF00270.29 KKK15443.1 - 7e-05 22.7 0.0 0.00015 21.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase PhoH PF02562.16 KKK15443.1 - 0.0024 17.4 0.0 0.006 16.1 0.0 1.6 1 0 0 1 1 1 1 PhoH-like protein ResIII PF04851.15 KKK15443.1 - 0.025 14.6 0.0 0.13 12.3 0.0 2.1 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit DUF2075 PF09848.9 KKK15443.1 - 0.051 12.8 0.1 0.28 10.4 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Helicase_RecD PF05127.14 KKK15443.1 - 0.088 12.7 0.0 3.6 7.4 0.0 2.4 2 0 0 2 2 2 0 Helicase IstB_IS21 PF01695.17 KKK15443.1 - 0.093 12.4 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein UvrD-helicase PF00580.21 KKK15443.1 - 0.13 11.7 0.1 0.38 10.2 0.0 1.8 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain HA2 PF04408.23 KKK15444.1 - 1.1e-23 83.5 0.1 1.1e-23 83.5 0.1 2.5 3 0 0 3 3 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KKK15444.1 - 2.5e-20 72.6 0.0 5.2e-20 71.6 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KKK15444.1 - 4.6e-13 49.5 0.0 1.1e-12 48.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain S1 PF00575.23 KKK15444.1 - 3.4e-10 40.1 1.4 6.9e-10 39.1 1.4 1.5 1 0 0 1 1 1 1 S1 RNA binding domain AAA_22 PF13401.6 KKK15444.1 - 0.0001 22.6 0.0 0.00026 21.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 KKK15444.1 - 0.00055 19.7 0.1 0.0015 18.3 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase T2SSE PF00437.20 KKK15444.1 - 0.00085 18.5 0.0 0.0021 17.2 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_30 PF13604.6 KKK15444.1 - 0.0023 17.7 0.0 0.0057 16.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KKK15444.1 - 0.017 15.5 0.0 0.036 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KKK15444.1 - 0.088 13.2 0.0 0.32 11.4 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 KKK15444.1 - 0.2 12.1 0.4 3.6 8.1 0.2 2.6 1 1 0 2 2 2 0 ABC transporter PRP38 PF03371.15 KKK15446.1 - 6e-64 215.1 0.0 7.8e-64 214.7 0.0 1.0 1 0 0 1 1 1 1 PRP38 family DUF1566 PF07603.11 KKK15446.1 - 0.083 13.3 0.0 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1566) SmpA_OmlA PF04355.13 KKK15452.1 - 0.042 13.6 0.0 0.066 13.0 0.0 1.3 1 0 0 1 1 1 0 SmpA / OmlA family Transp_cyt_pur PF02133.15 KKK15455.1 - 1.2e-27 96.8 31.2 1.6e-27 96.4 31.2 1.2 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF2826 PF11442.8 KKK15455.1 - 0.04 13.8 0.1 0.1 12.4 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2826) Dak1 PF02733.17 KKK15456.1 - 3.6e-99 331.6 0.0 4.9e-99 331.1 0.0 1.2 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 KKK15456.1 - 1.4e-40 139.0 0.8 2.2e-40 138.4 0.8 1.3 1 0 0 1 1 1 1 DAK2 domain SKG6 PF08693.10 KKK15457.1 - 5.3e-07 28.9 1.0 5.3e-07 28.9 1.0 1.8 2 0 0 2 2 2 1 Transmembrane alpha-helix domain SSP160 PF06933.11 KKK15457.1 - 0.16 10.1 22.3 0.21 9.7 22.3 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Glyco_transf_34 PF05637.12 KKK15458.1 - 1.6e-17 64.1 0.0 3.7e-10 39.9 0.0 2.2 1 1 1 2 2 2 2 galactosyl transferase GMA12/MNN10 family DUF273 PF03314.14 KKK15458.1 - 0.042 13.4 0.0 0.061 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF273 Pkinase_Tyr PF07714.17 KKK15459.1 - 4.7e-21 75.3 0.0 1.1e-20 74.0 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KKK15459.1 - 1.1e-20 74.1 0.0 2e-20 73.3 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain RIO1 PF01163.22 KKK15459.1 - 0.0032 17.1 0.0 0.049 13.2 0.0 2.0 2 0 0 2 2 2 1 RIO1 family PLD_C PF12357.8 KKK15459.1 - 0.0042 17.0 0.0 0.035 14.0 0.0 2.1 2 0 0 2 2 2 1 Phospholipase D C terminal Kdo PF06293.14 KKK15459.1 - 0.014 14.8 0.2 0.023 14.0 0.2 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PBP PF01161.20 KKK15460.1 - 5.6e-15 55.8 0.0 6.9e-15 55.5 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein NPP1 PF05630.11 KKK15461.1 - 2.8e-54 184.2 0.0 3.5e-54 183.9 0.0 1.0 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) HLH PF00010.26 KKK15469.1 - 1.2e-12 47.6 0.1 2.2e-12 46.7 0.1 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Tmemb_cc2 PF10267.9 KKK15469.1 - 0.02 14.1 2.9 0.023 13.9 2.9 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Kinesin_assoc PF16183.5 KKK15469.1 - 0.19 11.8 2.4 0.26 11.4 2.4 1.2 1 0 0 1 1 1 0 Kinesin-associated PRKG1_interact PF15898.5 KKK15469.1 - 1.6 9.6 6.6 20 6.2 6.6 2.1 1 1 0 1 1 1 0 cGMP-dependent protein kinase interacting domain IMS PF00817.20 KKK15488.1 - 1.5e-41 141.9 1.5 2.1e-41 141.4 0.5 1.8 2 0 0 2 2 2 1 impB/mucB/samB family IMS_C PF11799.8 KKK15488.1 - 2.7e-15 57.1 1.0 1.5e-13 51.4 0.2 3.1 4 0 0 4 4 4 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 KKK15488.1 - 3.7e-05 23.8 0.0 0.0001 22.4 0.0 1.8 1 0 0 1 1 1 1 IMS family HHH motif Sec34 PF04136.15 KKK15488.1 - 0.67 9.8 5.3 0.51 10.2 0.6 2.4 2 0 0 2 2 2 0 Sec34-like family DivIVA PF05103.13 KKK15489.1 - 0.21 11.6 0.8 14 5.8 0.1 2.3 2 0 0 2 2 2 0 DivIVA protein NIBRIN_BRCT_II PF16508.5 KKK15490.1 - 9e-37 126.0 0.0 4.7e-36 123.7 0.0 2.3 2 0 0 2 2 2 1 Second BRCT domain on Nijmegen syndrome breakage protein FHA PF00498.26 KKK15490.1 - 2.8e-08 34.0 0.3 7e-08 32.7 0.3 1.7 1 0 0 1 1 1 1 FHA domain Rbsn PF11464.8 KKK15490.1 - 0.013 15.3 2.5 0.043 13.5 2.5 1.9 1 0 0 1 1 1 0 Rabenosyn Rab binding domain RTT107_BRCT_5 PF16770.5 KKK15490.1 - 0.072 13.0 0.0 0.19 11.6 0.0 1.7 1 0 0 1 1 1 0 Regulator of Ty1 transposition protein 107 BRCT domain Yop-YscD_cpl PF16697.5 KKK15490.1 - 0.085 13.2 0.1 1.2 9.5 0.1 2.5 1 1 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain F-box-like PF12937.7 KKK15491.1 - 0.0017 18.2 0.0 0.0072 16.2 0.0 2.2 1 1 0 1 1 1 1 F-box-like Sugar_tr PF00083.24 KKK15494.1 - 4.2e-98 329.2 25.1 4.7e-98 329.0 25.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKK15494.1 - 4.6e-29 101.4 58.1 1.3e-26 93.4 30.6 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KKK15494.1 - 5.1e-06 25.2 6.4 5.1e-06 25.2 6.4 1.8 2 1 1 3 3 3 1 Fungal trichothecene efflux pump (TRI12) Myb_DNA-bind_6 PF13921.6 KKK15495.1 - 6.7e-17 61.5 1.4 9.4e-11 41.8 0.4 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KKK15495.1 - 7.7e-17 61.2 5.2 6.4e-10 39.1 0.2 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 KKK15495.1 - 0.0054 17.1 1.2 0.03 14.7 1.2 2.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 KKK15495.1 - 0.013 15.8 1.8 3.4 8.0 0.4 3.1 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Glyco_transf_24 PF18404.1 KKK15496.1 - 4.3e-149 495.2 2.2 7.6e-149 494.4 0.8 2.1 2 0 0 2 2 2 1 Glucosyltransferase 24 Thioredoxin_14 PF18402.1 KKK15496.1 - 7.3e-66 222.7 0.0 8.9e-65 219.2 0.0 2.5 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_12 PF18400.1 KKK15496.1 - 1.2e-48 165.5 0.3 2.8e-48 164.3 0.0 1.8 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_13 PF18401.1 KKK15496.1 - 7.3e-45 152.2 2.1 7.9e-43 145.6 0.1 3.5 4 0 0 4 4 4 1 Thioredoxin-like domain Thioredoxin_15 PF18403.1 KKK15496.1 - 1.4e-43 149.3 0.0 9.7e-41 140.0 0.0 3.1 3 0 0 3 3 3 1 Thioredoxin-like domain UDP-g_GGTase PF06427.11 KKK15496.1 - 2.6e-42 143.3 0.0 5.2e-42 142.4 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Glyco_transf_8 PF01501.20 KKK15496.1 - 0.00049 19.7 0.0 0.00087 18.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 8 TauD PF02668.16 KKK15497.1 - 5.8e-22 78.8 0.0 2.9e-21 76.5 0.0 1.9 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family HAD_2 PF13419.6 KKK15497.1 - 1.2e-12 48.3 0.0 2.6e-12 47.2 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KKK15497.1 - 1.8e-08 34.3 0.1 4.3e-08 33.1 0.1 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 KKK15497.1 - 1.5e-06 28.8 0.1 4.5e-06 27.2 0.1 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KKK15497.1 - 1.8e-05 25.1 0.0 0.042 14.1 0.0 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase CsiD PF08943.10 KKK15497.1 - 0.00048 19.3 0.0 0.00099 18.3 0.0 1.5 1 1 0 1 1 1 1 CsiD KH_6 PF15985.5 KKK15498.1 - 2.9e-17 62.7 0.0 5.5e-17 61.8 0.0 1.5 1 0 0 1 1 1 1 KH domain Rrp40_N PF18311.1 KKK15498.1 - 3.1e-12 46.2 1.6 8.3e-12 44.9 1.5 1.8 2 0 0 2 2 2 1 Exosome complex exonuclease Rrp40 N-terminal domain PerC PF06069.11 KKK15498.1 - 0.16 12.2 0.0 0.34 11.2 0.0 1.5 2 0 0 2 2 2 0 PerC transcriptional activator HSP70 PF00012.20 KKK15499.1 - 1.8e-85 287.4 0.8 2.4e-85 287.0 0.8 1.1 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KKK15499.1 - 8.1e-11 41.3 0.2 1.2e-10 40.8 0.2 1.3 1 0 0 1 1 1 1 MreB/Mbl protein Peripla_BP_6 PF13458.6 KKK15499.1 - 0.012 15.3 1.3 0.084 12.5 0.4 2.1 1 1 0 2 2 2 0 Periplasmic binding protein NADHdh PF00146.21 KKK15501.1 - 0.14 11.4 0.1 0.14 11.4 0.1 1.0 1 0 0 1 1 1 0 NADH dehydrogenase FAD_binding_4 PF01565.23 KKK15518.1 - 0.011 15.5 0.1 0.019 14.7 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain eIF2A PF08662.11 KKK15519.1 - 1.8e-69 233.5 0.0 8.6e-39 133.4 0.0 3.2 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A WD40 PF00400.32 KKK15519.1 - 0.04 14.8 1.4 6 7.9 0.0 4.2 3 1 0 3 3 3 0 WD domain, G-beta repeat CDV3 PF15359.6 KKK15519.1 - 0.16 12.4 3.8 0.49 10.9 0.2 2.6 2 0 0 2 2 2 0 Carnitine deficiency-associated protein 3 PD40 PF07676.12 KKK15519.1 - 0.32 11.0 2.3 12 6.0 0.1 4.0 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat FAT PF02259.23 KKK15524.1 - 3.5e-138 460.5 0.5 3.5e-138 460.5 0.5 2.2 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.27 KKK15524.1 - 9.4e-71 238.5 0.1 1.9e-70 237.5 0.1 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.8 KKK15524.1 - 1.5e-67 226.5 3.2 9.5e-63 210.9 0.4 5.2 4 1 1 5 5 5 2 Domain of unknown function (DUF3385) FRB_dom PF08771.11 KKK15524.1 - 5.1e-43 145.5 8.0 1.7e-42 143.9 0.2 4.6 5 0 0 5 5 3 1 FKBP12-rapamycin binding domain HEAT_2 PF13646.6 KKK15524.1 - 1.6e-14 54.0 12.6 0.00014 22.2 0.0 9.1 8 2 1 9 9 8 3 HEAT repeats FATC PF02260.20 KKK15524.1 - 9.1e-14 51.0 1.0 2.6e-13 49.5 1.0 1.9 1 0 0 1 1 1 1 FATC domain HEAT_EZ PF13513.6 KKK15524.1 - 1e-13 51.4 14.2 0.0033 17.9 0.0 9.8 11 1 0 11 11 9 3 HEAT-like repeat HEAT PF02985.22 KKK15524.1 - 1.3e-10 40.6 22.8 0.0047 17.1 0.0 12.2 14 0 0 14 14 11 2 HEAT repeat Adaptin_N PF01602.20 KKK15524.1 - 8.3e-07 27.9 9.6 0.00049 18.8 0.4 4.7 3 2 1 4 4 4 3 Adaptin N terminal region CLASP_N PF12348.8 KKK15524.1 - 0.00021 20.9 0.8 1 8.8 0.0 4.7 5 0 0 5 5 5 1 CLASP N terminal MMS19_C PF12460.8 KKK15524.1 - 0.0025 17.0 5.6 0.11 11.6 0.0 3.9 3 1 0 3 3 3 1 RNAPII transcription regulator C-terminal Tti2 PF10521.9 KKK15524.1 - 0.003 17.2 1.2 14 5.1 0.0 4.8 3 1 2 5 5 5 0 Tti2 family Sec7_N PF12783.7 KKK15524.1 - 0.0065 16.4 0.0 0.52 10.2 0.0 3.6 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal TPR_11 PF13414.6 KKK15524.1 - 0.031 14.0 0.5 0.63 9.8 0.0 3.0 2 0 0 2 2 2 0 TPR repeat DUF3730 PF12530.8 KKK15524.1 - 0.046 13.3 0.9 4.1 6.9 0.0 4.1 5 0 0 5 5 5 0 Protein of unknown function (DUF3730) PDZ_6 PF17820.1 KKK15524.1 - 0.071 13.0 0.0 0.18 11.7 0.0 1.7 1 0 0 1 1 1 0 PDZ domain DUF3150 PF11348.8 KKK15524.1 - 0.1 11.8 0.0 0.24 10.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3150) DUF1997 PF09366.10 KKK15524.1 - 0.12 12.5 0.1 0.99 9.5 0.0 2.6 3 0 0 3 3 1 0 Protein of unknown function (DUF1997) TPR_14 PF13428.6 KKK15524.1 - 0.22 12.4 11.7 5 8.2 0.0 5.9 5 1 1 6 6 4 0 Tetratricopeptide repeat SH3_1 PF00018.28 KKK15525.1 - 1.2e-09 37.7 0.1 3e-09 36.4 0.1 1.8 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KKK15525.1 - 4.4e-09 35.9 0.0 8.7e-09 34.9 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 KKK15525.1 - 6.7e-09 35.5 0.1 1.9e-08 34.1 0.1 1.8 1 0 0 1 1 1 1 Variant SH3 domain Chorismate_synt PF01264.21 KKK15526.1 - 1.1e-138 461.5 0.0 1.2e-138 461.3 0.0 1.0 1 0 0 1 1 1 1 Chorismate synthase BPL_LplA_LipB PF03099.19 KKK15528.1 - 1e-07 31.9 0.0 2.2e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Formyl_trans_N PF00551.19 KKK15530.1 - 8.4e-20 71.3 0.0 3e-19 69.5 0.0 1.8 2 0 0 2 2 2 1 Formyl transferase Formyl_trans_C PF02911.18 KKK15530.1 - 0.0012 19.1 0.1 0.0031 17.7 0.1 1.7 1 1 0 1 1 1 1 Formyl transferase, C-terminal domain DUF1712 PF08217.11 KKK15531.1 - 5.1e-17 61.6 0.0 2.8e-15 55.9 0.0 2.1 2 0 0 2 2 2 2 Fungal domain of unknown function (DUF1712) Alg14 PF08660.11 KKK15532.1 - 2.6e-58 196.8 0.0 4.3e-58 196.1 0.0 1.3 1 1 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like DUF624 PF04854.14 KKK15532.1 - 0.042 14.0 0.2 0.16 12.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function, DUF624 adh_short_C2 PF13561.6 KKK15533.1 - 2.5e-42 145.1 0.5 3.3e-42 144.7 0.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KKK15533.1 - 1.8e-40 138.5 0.1 2.4e-40 138.1 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KKK15533.1 - 1.1e-10 41.8 0.7 1.5e-10 41.3 0.7 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KKK15533.1 - 0.0051 16.3 0.1 1.6 8.1 0.0 2.9 2 1 0 2 2 2 2 NAD dependent epimerase/dehydratase family Sugar_tr PF00083.24 KKK15534.1 - 0.00023 20.2 0.4 0.00025 20.0 0.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter Ima1_N PF09779.9 KKK15535.1 - 4.1e-35 121.6 2.0 8.4e-35 120.6 2.0 1.6 1 0 0 1 1 1 1 Ima1 N-terminal domain OrfB_Zn_ribbon PF07282.11 KKK15535.1 - 0.71 9.8 2.4 1.8 8.5 2.4 1.7 1 0 0 1 1 1 0 Putative transposase DNA-binding domain DZR PF12773.7 KKK15535.1 - 3.6 7.7 8.4 3.4 7.8 1.5 2.6 2 1 0 2 2 2 0 Double zinc ribbon DUF2264 PF10022.9 KKK15536.1 - 3.2e-141 470.5 0.0 3.9e-141 470.2 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2264) Sugar_tr PF00083.24 KKK15537.1 - 8e-108 361.2 18.7 9e-108 361.0 18.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKK15537.1 - 3e-21 75.8 27.4 4.1e-21 75.3 27.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Fungal_trans_2 PF11951.8 KKK15539.1 - 2.7e-52 177.9 0.0 4.2e-52 177.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK15539.1 - 2.4e-05 24.4 3.8 5.8e-05 23.1 3.8 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mannosyl_trans3 PF11051.8 KKK15540.1 - 5.4e-59 199.8 0.0 8.9e-36 123.6 0.0 2.1 1 1 1 2 2 2 2 Mannosyltransferase putative Kinesin PF00225.23 KKK15542.1 - 1.2e-90 303.8 0.0 1.2e-90 303.8 0.0 2.6 3 0 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 KKK15542.1 - 1.2e-18 67.4 0.0 4.8e-15 55.8 0.0 3.0 1 1 1 2 2 2 2 Microtubule binding DUF2937 PF11157.8 KKK15542.1 - 6.1 6.5 16.6 0.43 10.3 4.3 4.2 3 1 0 3 3 3 0 Protein of unknown function (DUF2937) BCIP PF13862.6 KKK15544.1 - 9.7e-76 254.1 0.0 1.3e-75 253.7 0.0 1.2 1 0 0 1 1 1 1 p21-C-terminal region-binding protein VID27_N PF17748.1 KKK15544.1 - 0.09 12.6 0.3 0.16 11.8 0.3 1.3 1 0 0 1 1 1 0 VID27 N-terminal region Sad1_UNC PF07738.13 KKK15545.1 - 4.5e-13 49.4 0.0 1.3e-06 28.5 0.0 2.7 3 0 0 3 3 3 2 Sad1 / UNC-like C-terminal WD40 PF00400.32 KKK15546.1 - 2.4e-27 94.6 12.8 1.5e-05 25.6 0.8 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.8 KKK15546.1 - 3.1e-09 36.0 3.2 0.0019 16.9 0.1 5.0 3 1 2 5 5 5 4 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 KKK15546.1 - 1.3e-06 28.6 0.2 0.23 11.8 0.0 4.5 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain APG6_N PF17675.1 KKK15546.1 - 0.0042 17.6 3.3 0.0082 16.7 3.3 1.5 1 0 0 1 1 1 1 Apg6 coiled-coil region Nucleo_P87 PF07267.11 KKK15546.1 - 0.13 11.0 1.3 0.18 10.7 0.6 1.4 1 1 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 ROS_MUCR PF05443.11 KKK15546.1 - 0.16 12.0 1.8 1 9.4 0.3 2.7 3 0 0 3 3 3 0 ROS/MUCR transcriptional regulator protein PEARLI-4 PF05278.12 KKK15546.1 - 0.22 11.1 2.6 0.36 10.4 2.6 1.3 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) Spc24 PF08286.11 KKK15546.1 - 0.62 10.3 3.1 0.33 11.2 0.6 1.8 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 DUF1664 PF07889.12 KKK15546.1 - 2.7 8.0 4.4 8 6.5 1.7 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) HSP70 PF00012.20 KKK15548.1 - 0.0043 15.3 0.0 0.017 13.3 0.0 1.7 1 1 0 1 1 1 1 Hsp70 protein DUF2482 PF10655.9 KKK15548.1 - 0.38 11.3 1.2 1 9.9 1.2 1.7 1 0 0 1 1 1 0 Hypothetical protein of unknown function (DUF2482) FKBP_C PF00254.28 KKK15550.1 - 2.6e-33 114.2 0.0 3e-33 114.0 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase IBR PF01485.21 KKK15553.1 - 4.6e-06 26.8 2.5 4.6e-06 26.8 2.5 4.7 4 1 0 4 4 4 2 IBR domain, a half RING-finger domain DMA PF03474.14 KKK15553.1 - 0.01 15.4 0.0 0.16 11.6 0.0 2.4 2 0 0 2 2 2 0 DMRTA motif Chalcone_2 PF16035.5 KKK15553.1 - 0.075 12.8 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Chalcone isomerase like Lactonase PF10282.9 KKK15554.1 - 5.3e-20 72.0 0.2 6.8e-20 71.6 0.2 1.1 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Cation_efflux PF01545.21 KKK15556.1 - 2.2e-15 56.9 6.8 2.9e-15 56.6 6.8 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 KKK15556.1 - 3.8e-11 42.9 0.7 7.3e-11 42.0 0.1 1.7 2 0 0 2 2 2 1 Dimerisation domain of Zinc Transporter DUF3237 PF11578.8 KKK15557.1 - 3.8e-47 159.9 0.1 4.2e-47 159.7 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) EMP24_GP25L PF01105.24 KKK15558.1 - 1.5e-49 168.4 0.5 1.7e-49 168.2 0.5 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD 14-3-3 PF00244.20 KKK15559.1 - 3e-09 36.7 0.1 5.3e-09 35.9 0.1 1.3 1 0 0 1 1 1 1 14-3-3 protein Metallophos PF00149.28 KKK15560.1 - 7.6e-10 39.6 1.6 8.3e-10 39.5 0.5 1.7 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Coilin_N PF15862.5 KKK15560.1 - 0.0095 15.7 0.0 0.15 11.8 0.0 2.6 2 1 0 2 2 2 1 Coilin N-terminus SR-25 PF10500.9 KKK15560.1 - 0.44 10.1 7.6 0.031 13.9 1.2 1.9 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein SPT6_acidic PF14632.6 KKK15560.1 - 8.3 7.1 10.5 13 6.4 0.7 2.4 2 0 0 2 2 2 0 Acidic N-terminal SPT6 PAM2 PF07145.15 KKK15561.1 - 3.8e-05 23.1 7.7 0.054 13.2 0.0 4.8 5 0 0 5 5 5 3 Ataxin-2 C-terminal region NICE-3 PF07406.11 KKK15561.1 - 0.24 11.4 3.7 0.15 12.0 0.6 2.2 2 0 0 2 2 2 0 NICE-3 protein Myb_DNA-bind_6 PF13921.6 KKK15562.1 - 4.8e-05 23.5 0.9 0.0076 16.5 0.2 2.6 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KKK15562.1 - 9.8e-05 22.5 8.0 0.0069 16.6 0.2 3.0 3 0 0 3 3 3 2 Myb-like DNA-binding domain RXT2_N PF08595.11 KKK15562.1 - 0.023 14.7 2.6 0.034 14.2 2.6 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal NOA36 PF06524.12 KKK15562.1 - 0.049 13.0 5.2 0.061 12.6 5.2 1.1 1 0 0 1 1 1 0 NOA36 protein SURF2 PF05477.11 KKK15562.1 - 0.068 12.9 1.6 0.095 12.4 1.6 1.2 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) RNase_H2_suC PF08615.11 KKK15562.1 - 0.077 13.2 0.6 0.086 13.0 0.6 1.1 1 0 0 1 1 1 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) PBP1_TM PF14812.6 KKK15562.1 - 0.14 12.5 4.9 0.29 11.5 4.9 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CENP-B_dimeris PF09026.10 KKK15562.1 - 0.22 11.9 9.8 0.4 11.1 9.8 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain FAM176 PF14851.6 KKK15562.1 - 0.3 10.7 3.3 0.44 10.2 3.3 1.3 1 0 0 1 1 1 0 FAM176 family DUF4611 PF15387.6 KKK15562.1 - 0.82 9.9 7.4 1.4 9.2 7.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) DNA_pol_phi PF04931.13 KKK15562.1 - 2.3 6.2 8.3 2.8 5.9 8.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi Glyco_hydro_17 PF00332.18 KKK15563.1 - 2.7e-34 119.2 1.7 2.1e-33 116.3 1.7 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 Lactamase_B PF00753.27 KKK15573.1 - 2.7e-06 27.6 1.4 0.00024 21.2 0.2 2.3 1 1 0 2 2 2 2 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KKK15573.1 - 0.00087 18.9 1.2 0.0023 17.5 0.1 2.0 2 0 0 2 2 2 1 Beta-lactamase superfamily domain ABC1 PF03109.16 KKK15574.1 - 5.7e-21 74.9 0.9 2.6e-20 72.8 0.0 2.3 2 1 0 2 2 2 1 ABC1 family PBP PF01161.20 KKK15600.1 - 1.7e-08 34.9 0.0 3e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein CBS PF00571.28 KKK15601.1 - 3.7e-22 78.5 6.1 4.8e-10 39.7 0.1 3.8 4 0 0 4 4 4 3 CBS domain Kinesin PF00225.23 KKK15604.1 - 2.8e-113 378.2 0.0 2.8e-113 378.2 0.0 2.1 3 0 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 KKK15604.1 - 4.4e-25 88.4 0.0 1.5e-24 86.6 0.0 1.9 2 0 0 2 2 2 1 Microtubule binding DUF2458 PF10454.9 KKK15604.1 - 0.064 12.9 15.1 0.46 10.1 1.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2458) MukB PF04310.12 KKK15604.1 - 2.2 8.0 5.5 24 4.7 1.7 2.7 3 0 0 3 3 3 0 MukB N-terminal Pterin_bind PF00809.22 KKK15604.1 - 2.9 7.5 5.5 11 5.6 0.2 2.2 2 0 0 2 2 2 0 Pterin binding enzyme FUSC PF04632.12 KKK15604.1 - 4.2 5.8 13.1 2 6.9 9.8 1.8 2 0 0 2 2 2 0 Fusaric acid resistance protein family Tau95 PF09734.9 KKK15604.1 - 6.2 7.6 5.9 1.1 10.1 1.7 1.9 2 0 0 2 2 2 0 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain DUF1275 PF06912.11 KKK15605.1 - 2.1e-47 161.6 10.9 2.4e-47 161.3 10.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) DUF3040 PF11239.8 KKK15605.1 - 0.033 14.5 2.3 0.34 11.2 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3040) Apc13p PF05839.11 KKK15606.1 - 6.1e-18 64.8 0.0 1.5e-17 63.5 0.0 1.7 2 0 0 2 2 2 1 Apc13p protein CRAL_TRIO PF00650.20 KKK15607.1 - 2.3e-37 128.2 0.0 3.7e-37 127.5 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KKK15607.1 - 1.3e-15 57.3 0.1 2.5e-15 56.4 0.1 1.5 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 KKK15607.1 - 0.0003 20.9 0.0 0.00051 20.2 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain TraK PF06586.11 KKK15607.1 - 0.024 14.4 1.6 0.038 13.7 1.6 1.3 1 0 0 1 1 1 0 TraK protein IF-2B PF01008.17 KKK15608.1 - 5.9e-75 252.1 0.0 7.4e-75 251.8 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family Ndc1_Nup PF09531.10 KKK15608.1 - 0.11 11.2 3.6 0.15 10.7 3.6 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Pol_alpha_B_N PF08418.10 KKK15609.1 - 6.6e-61 206.4 0.0 1.9e-31 109.9 0.0 2.5 2 1 1 3 3 3 2 DNA polymerase alpha subunit B N-terminal DNA_pol_E_B PF04042.16 KKK15609.1 - 1.3e-37 129.3 0.0 1.8e-37 128.7 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Ribosomal_L4 PF00573.22 KKK15610.1 - 3.3e-44 150.9 0.0 3.9e-44 150.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family ECH_2 PF16113.5 KKK15611.1 - 2e-129 431.9 0.0 2.7e-129 431.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 KKK15611.1 - 9.1e-25 87.4 0.0 1.9e-24 86.4 0.0 1.5 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase FPN1 PF06963.12 KKK15612.1 - 7e-152 506.0 17.9 1.9e-151 504.6 18.2 1.5 2 0 0 2 2 2 1 Ferroportin1 (FPN1) Fungal_trans_2 PF11951.8 KKK15612.1 - 3.1e-11 42.7 0.0 7.7e-11 41.4 0.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Gag_spuma PF03276.14 KKK15612.1 - 0.48 8.8 2.4 3.1 6.1 1.4 2.0 2 0 0 2 2 2 0 Spumavirus gag protein Sulfatase PF00884.23 KKK15613.1 - 6.9e-71 239.2 0.0 8.7e-71 238.8 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Sulfatase_C PF14707.6 KKK15613.1 - 0.011 16.5 0.1 0.28 11.9 0.1 2.6 1 1 0 1 1 1 0 C-terminal region of aryl-sulfatase DUF4994 PF16385.5 KKK15613.1 - 0.038 13.9 0.0 0.086 12.8 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function DUF4976 PF16347.5 KKK15613.1 - 0.08 13.2 0.0 0.24 11.7 0.0 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4976) bZIP_1 PF00170.21 KKK15614.1 - 9.4e-08 32.0 6.6 1.5e-07 31.4 6.6 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KKK15614.1 - 0.0068 16.5 8.6 0.013 15.5 8.6 1.4 1 0 0 1 1 1 1 Basic region leucine zipper IMUP PF15761.5 KKK15614.1 - 0.39 11.4 2.7 0.72 10.6 2.7 1.4 1 0 0 1 1 1 0 Immortalisation up-regulated protein bZIP_Maf PF03131.17 KKK15614.1 - 2.1 8.9 11.9 0.055 14.0 4.9 1.8 2 0 0 2 2 2 0 bZIP Maf transcription factor Rad60-SLD PF11976.8 KKK15618.1 - 2.6e-21 75.2 0.2 2.9e-21 75.0 0.2 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 KKK15618.1 - 1.1e-11 44.3 0.1 1.2e-11 44.1 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin family APH PF01636.23 KKK15619.1 - 0.02 14.8 0.1 0.03 14.2 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family SpoU_methylas_C PF12105.8 KKK15619.1 - 0.17 11.6 0.0 0.58 9.9 0.0 1.9 2 0 0 2 2 2 0 SpoU, rRNA methylase, C-terminal APH PF01636.23 KKK15620.1 - 0.069 13.1 0.2 0.26 11.2 0.2 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family Nup84_Nup100 PF04121.13 KKK15621.1 - 1.1e-168 562.6 1.3 2e-168 561.8 1.3 1.3 1 0 0 1 1 1 1 Nuclear pore protein 84 / 107 DNA_pol_phi PF04931.13 KKK15621.1 - 4.4 5.3 17.4 6.9 4.6 17.4 1.2 1 0 0 1 1 1 0 DNA polymerase phi CDP-OH_P_transf PF01066.21 KKK15622.1 - 3.9e-11 43.5 0.1 3.9e-11 43.5 0.1 2.2 3 0 0 3 3 3 1 CDP-alcohol phosphatidyltransferase WSC PF01822.19 KKK15623.1 - 3.4e-13 49.6 7.7 3.4e-13 49.6 7.7 2.2 2 0 0 2 2 2 1 WSC domain SKG6 PF08693.10 KKK15623.1 - 2.2e-09 36.5 0.5 2.2e-09 36.5 0.5 1.9 2 0 0 2 2 2 1 Transmembrane alpha-helix domain MGC-24 PF05283.11 KKK15623.1 - 0.0002 21.8 6.3 0.00032 21.2 6.3 1.3 1 0 0 1 1 1 1 Multi-glycosylated core protein 24 (MGC-24), sialomucin Alpha_GJ PF03229.13 KKK15623.1 - 0.0011 19.5 3.8 0.002 18.7 3.8 1.4 1 0 0 1 1 1 1 Alphavirus glycoprotein J Trp_oprn_chp PF09534.10 KKK15623.1 - 0.014 15.2 0.4 0.025 14.4 0.0 1.8 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF5305 PF17231.2 KKK15623.1 - 0.024 14.0 0.0 0.04 13.3 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5305) TrbL PF04610.14 KKK15623.1 - 0.05 13.3 1.0 0.075 12.8 1.0 1.2 1 0 0 1 1 1 0 TrbL/VirB6 plasmid conjugal transfer protein L1R_F9L PF02442.17 KKK15623.1 - 0.065 13.1 1.0 0.1 12.5 1.0 1.2 1 0 0 1 1 1 0 Lipid membrane protein of large eukaryotic DNA viruses TrbI PF03743.14 KKK15623.1 - 0.13 12.1 5.0 0.21 11.4 5.0 1.3 1 0 0 1 1 1 0 Bacterial conjugation TrbI-like protein Abhydrolase_6 PF12697.7 KKK15624.1 - 1.5e-11 45.3 0.0 2.2e-11 44.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KKK15624.1 - 2e-10 40.7 0.0 3.7e-10 39.9 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KKK15624.1 - 1.1e-05 24.9 0.0 1.4e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 KKK15624.1 - 0.00025 21.2 0.1 0.00057 20.1 0.1 1.6 1 1 0 1 1 1 1 Thioesterase domain Imm10 PF15588.6 KKK15624.1 - 0.13 12.4 0.0 0.24 11.6 0.0 1.4 1 0 0 1 1 1 0 Immunity protein 10 DUF604 PF04646.12 KKK15625.1 - 3.8e-14 52.7 0.4 8.9e-14 51.5 0.4 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF604 tRNA-synt_2b PF00587.25 KKK15626.1 - 1.8e-30 106.2 0.0 9.9e-28 97.3 0.0 2.7 2 0 0 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 KKK15626.1 - 8.2e-17 61.1 0.2 1.7e-16 60.1 0.2 1.6 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.14 KKK15626.1 - 1.2e-13 50.9 0.0 2.4e-13 49.9 0.0 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.21 KKK15626.1 - 0.00014 21.8 0.0 0.00028 20.8 0.0 1.5 1 0 0 1 1 1 1 TGS domain Gar1 PF04410.14 KKK15627.1 - 8.9e-40 136.0 0.0 1.1e-39 135.7 0.0 1.0 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region Acyl-CoA_dh_1 PF00441.24 KKK15631.1 - 1e-42 145.9 0.4 1.5e-42 145.4 0.4 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KKK15631.1 - 7.5e-22 77.3 0.1 1.3e-21 76.6 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Cyt-b5 PF00173.28 KKK15631.1 - 1.6e-19 69.8 0.3 3e-19 68.9 0.3 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_N PF02771.16 KKK15631.1 - 2.9e-19 69.8 0.0 5.8e-19 68.8 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 KKK15631.1 - 7.9e-10 39.1 0.0 1.3e-09 38.4 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl_transf_3 PF01757.22 KKK15632.1 - 2.5e-32 112.3 36.9 4.2e-32 111.5 36.9 1.4 1 1 0 1 1 1 1 Acyltransferase family UPF0182 PF03699.13 KKK15632.1 - 0.0087 14.3 0.5 0.016 13.4 0.5 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0182) Spt5-NGN PF03439.13 KKK15633.1 - 3.5e-25 87.7 0.0 5.9e-25 87.0 0.0 1.4 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section Spt5_N PF11942.8 KKK15633.1 - 2.1e-17 63.9 11.2 2.1e-17 63.9 11.2 4.5 2 1 2 4 4 4 1 Spt5 transcription elongation factor, acidic N-terminal CTD PF12815.7 KKK15633.1 - 2.7e-16 59.9 24.6 2.7e-13 50.3 14.0 4.5 2 2 1 3 3 3 2 Spt5 C-terminal nonapeptide repeat binding Spt4 KOW PF00467.29 KKK15633.1 - 7.1e-13 48.0 9.8 0.00046 20.0 0.8 4.9 5 0 0 5 5 5 3 KOW motif DUF3912 PF13051.6 KKK15633.1 - 8.8e-06 25.9 1.0 0.0037 17.5 0.0 3.0 3 0 0 3 3 3 2 Protein of unknown function (DUF3912) mRNA_triPase PF02940.15 KKK15634.1 - 4.4e-63 212.9 0.0 8.1e-63 212.1 0.0 1.4 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain PepSY PF03413.19 KKK15634.1 - 0.16 12.5 0.0 1.9 9.1 0.0 2.3 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain Peptidase_C12 PF01088.21 KKK15638.1 - 6.2e-62 209.1 0.0 8.6e-62 208.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 KKK15638.1 - 0.021 14.7 0.4 0.058 13.3 0.0 1.9 2 0 0 2 2 2 0 Ubiquitin carboxyl-terminal hydrolases I-set PF07679.16 KKK15639.1 - 0.012 15.7 0.2 1.6 8.9 0.0 4.0 5 0 0 5 5 5 0 Immunoglobulin I-set domain OTU PF02338.19 KKK15640.1 - 5e-08 33.5 0.0 8.5e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease Pkinase PF00069.25 KKK15641.1 - 8.5e-42 143.3 0.0 5.3e-19 68.6 0.0 3.1 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 KKK15641.1 - 2.4e-09 36.9 0.0 0.00057 19.2 0.0 3.1 2 1 1 3 3 3 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 KKK15641.1 - 0.013 14.3 0.0 0.022 13.6 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 KKK15641.1 - 0.022 14.7 0.3 0.97 9.3 0.1 2.4 2 1 1 3 3 3 0 Phosphotransferase enzyme family FTA2 PF13095.6 KKK15641.1 - 0.027 14.1 0.0 0.13 11.9 0.0 2.0 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Cnd1_N PF12922.7 KKK15642.1 - 3.2e-61 206.0 0.1 6.6e-61 205.0 0.1 1.6 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1, N-term Cnd1 PF12717.7 KKK15642.1 - 3.3e-47 160.6 2.7 6.4e-42 143.4 0.1 3.3 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KKK15642.1 - 1.1e-09 37.7 7.1 0.06 13.6 0.0 6.2 5 0 0 5 5 5 4 HEAT repeat HEAT_2 PF13646.6 KKK15642.1 - 1.2e-09 38.4 8.6 2e-05 24.9 0.1 4.2 5 0 0 5 5 5 2 HEAT repeats Adaptin_N PF01602.20 KKK15642.1 - 1.3e-06 27.3 7.7 0.038 12.6 0.3 4.1 3 2 0 3 3 3 3 Adaptin N terminal region HEAT_EZ PF13513.6 KKK15642.1 - 2.4e-05 24.7 10.2 0.46 11.0 0.1 6.2 6 0 0 6 6 6 2 HEAT-like repeat RTP1_C1 PF10363.9 KKK15642.1 - 0.00012 22.3 0.1 0.2 11.8 0.0 3.5 2 1 0 2 2 2 2 Required for nuclear transport of RNA pol II C-terminus 1 Cnd3 PF12719.7 KKK15642.1 - 0.00081 18.7 0.4 0.00081 18.7 0.4 3.0 4 1 0 4 4 4 1 Nuclear condensing complex subunits, C-term domain Oxysterol_BP PF01237.18 KKK15643.1 - 1.2e-53 182.3 0.0 3.1e-51 174.4 0.0 2.1 1 1 0 1 1 1 1 Oxysterol-binding protein Abhydrolase_6 PF12697.7 KKK15644.1 - 1.3e-05 25.9 1.5 1.8e-05 25.4 1.5 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KKK15644.1 - 0.048 12.9 0.0 0.68 9.2 0.0 2.1 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Esterase PF00756.20 KKK15644.1 - 0.21 11.2 0.0 0.33 10.5 0.0 1.2 1 0 0 1 1 1 0 Putative esterase Ion_trans_2 PF07885.16 KKK15645.1 - 6.8e-25 86.8 22.8 1e-14 54.2 9.1 3.4 3 1 0 3 3 3 2 Ion channel Ion_trans PF00520.31 KKK15645.1 - 0.0023 17.2 19.0 0.17 11.1 0.3 3.2 2 1 1 3 3 3 3 Ion transport protein Alkyl_sulf_dimr PF14863.6 KKK15646.1 - 0.096 13.1 0.1 0.16 12.4 0.1 1.3 1 0 0 1 1 1 0 Alkyl sulfatase dimerisation Bromodomain PF00439.25 KKK15647.1 - 4.5e-38 129.2 4.6 1.9e-20 72.7 0.3 2.5 2 0 0 2 2 2 2 Bromodomain BAH PF01426.18 KKK15647.1 - 6e-19 68.1 1.3 1.3e-18 67.0 1.3 1.6 1 0 0 1 1 1 1 BAH domain CDC45 PF02724.14 KKK15647.1 - 0.0013 17.1 6.1 0.0013 17.1 6.1 2.0 2 0 0 2 2 2 1 CDC45-like protein HHH_6 PF14579.6 KKK15647.1 - 0.069 13.4 0.1 12 6.2 0.0 2.8 2 0 0 2 2 2 0 Helix-hairpin-helix motif CENP-B_dimeris PF09026.10 KKK15647.1 - 0.65 10.4 11.9 2.1 8.8 11.9 1.8 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Stathmin PF00836.19 KKK15647.1 - 2 8.4 11.9 3.2 7.7 10.9 1.8 1 1 0 1 1 1 0 Stathmin family HTH_32 PF13565.6 KKK15647.1 - 6.2 7.5 11.7 1.4 9.6 1.2 3.6 3 1 0 3 3 3 0 Homeodomain-like domain Histone PF00125.24 KKK15648.1 - 1.4e-21 77.2 0.5 1.7e-21 76.9 0.5 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KKK15648.1 - 0.0004 20.6 0.0 0.0004 20.6 0.0 1.7 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 KKK15648.1 - 0.00049 20.5 0.0 0.00082 19.8 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A RP-C PF03428.13 KKK15648.1 - 0.052 13.2 0.1 0.12 12.0 0.1 1.5 1 1 0 1 1 1 0 Replication protein C N-terminal domain YscO-like PF16789.5 KKK15648.1 - 0.064 13.3 0.1 0.074 13.1 0.1 1.1 1 0 0 1 1 1 0 YscO-like protein Peptidase_C54 PF03416.19 KKK15649.1 - 1.1e-96 323.5 0.0 1.3e-96 323.3 0.0 1.0 1 0 0 1 1 1 1 Peptidase family C54 Complex1_LYR PF05347.15 KKK15650.1 - 2.7e-10 40.1 0.3 3.8e-10 39.7 0.3 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Histone_H2A_C PF16211.5 KKK15651.1 - 4.5e-21 74.3 2.6 8e-21 73.5 2.6 1.4 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 KKK15651.1 - 6.6e-17 62.1 0.0 8.9e-17 61.7 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KKK15651.1 - 9.5e-06 25.8 0.0 1.3e-05 25.4 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone PCMT PF01135.19 KKK15652.1 - 6.9e-55 186.0 0.0 2.1e-54 184.5 0.0 1.6 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 KKK15652.1 - 7.7e-09 35.5 0.0 9.9e-09 35.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKK15652.1 - 9.2e-07 29.5 0.0 1.6e-06 28.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 KKK15652.1 - 4.2e-05 23.6 0.0 6.2e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KKK15652.1 - 6.5e-05 22.8 0.0 9.2e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KKK15652.1 - 0.00065 20.3 0.0 0.0011 19.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KKK15652.1 - 0.0033 18.1 0.0 0.0052 17.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 KKK15652.1 - 0.0067 16.0 0.0 0.0095 15.5 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW MTS PF05175.14 KKK15652.1 - 0.021 14.4 0.0 0.037 13.6 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase small domain PrmA PF06325.13 KKK15652.1 - 0.037 13.4 0.0 0.051 13.0 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.18 KKK15652.1 - 0.051 12.9 0.0 0.072 12.4 0.0 1.1 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family FtsJ PF01728.19 KKK15652.1 - 0.08 13.0 0.0 0.11 12.6 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase GCD14 PF08704.10 KKK15652.1 - 0.091 12.4 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit RrnaAD PF00398.20 KKK15652.1 - 0.21 10.6 0.0 0.27 10.2 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase 2-oxoacid_dh PF00198.23 KKK15653.1 - 2e-80 269.6 0.1 3.7e-80 268.7 0.0 1.4 2 0 0 2 2 2 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 KKK15653.1 - 8.9e-19 67.1 1.8 1.7e-18 66.2 1.8 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 KKK15653.1 - 0.00014 21.6 0.2 0.0056 16.5 0.1 2.4 1 1 1 2 2 2 1 Biotin-lipoyl like HlyD_3 PF13437.6 KKK15653.1 - 0.00095 19.8 0.1 0.23 12.2 0.0 2.5 1 1 1 2 2 2 1 HlyD family secretion protein RnfC_N PF13375.6 KKK15653.1 - 0.0077 16.2 0.2 0.057 13.4 0.0 2.2 1 1 1 2 2 2 1 RnfC Barrel sandwich hybrid domain HlyD_D23 PF16576.5 KKK15653.1 - 0.0078 15.5 0.2 2.2 7.4 0.0 2.4 1 1 1 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion GCV_H PF01597.19 KKK15653.1 - 0.016 15.1 0.4 0.033 14.1 0.4 1.5 1 0 0 1 1 1 0 Glycine cleavage H-protein Ndc1_Nup PF09531.10 KKK15653.1 - 1.5 7.4 3.2 1.9 7.1 3.2 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup FAP PF07174.11 KKK15653.1 - 3.3 7.1 14.9 5.1 6.5 14.9 1.2 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) MSA-2c PF12238.8 KKK15653.1 - 5.8 6.9 7.9 11 6.0 7.9 1.5 1 0 0 1 1 1 0 Merozoite surface antigen 2c Helicase_C_2 PF13307.6 KKK15654.1 - 2.1e-51 174.5 0.0 5.2e-51 173.2 0.0 1.6 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.15 KKK15654.1 - 1.2e-50 171.5 0.0 2.1e-50 170.8 0.0 1.4 1 0 0 1 1 1 1 DEAD_2 Ribosomal_L27A PF00828.19 KKK15654.1 - 3.6e-21 76.2 0.0 7.3e-21 75.2 0.0 1.5 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A HBB PF06777.11 KKK15654.1 - 0.00079 19.2 0.0 0.0024 17.6 0.0 1.8 1 0 0 1 1 1 1 Helical and beta-bridge domain DEAD PF00270.29 KKK15654.1 - 0.0032 17.3 0.0 2 8.1 0.0 2.4 2 0 0 2 2 2 2 DEAD/DEAH box helicase Dor1 PF04124.12 KKK15654.1 - 0.011 14.5 0.7 0.02 13.6 0.7 1.3 1 0 0 1 1 1 0 Dor1-like family SH3-WW_linker PF16618.5 KKK15654.1 - 5.4 7.4 5.8 5 7.6 2.4 2.2 2 0 0 2 2 2 0 Linker region between SH3 and WW domains on ARHGAP12 Sel1 PF08238.12 KKK15655.1 - 7.2e-07 29.7 7.2 0.0018 18.9 0.2 3.6 3 1 0 3 3 3 3 Sel1 repeat TPR_1 PF00515.28 KKK15655.1 - 4.1e-05 23.2 0.0 0.00027 20.6 0.0 2.4 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 KKK15655.1 - 0.0029 18.3 0.2 0.037 14.9 0.0 2.9 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 KKK15655.1 - 0.0076 16.3 0.0 0.0076 16.3 0.0 2.8 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 KKK15655.1 - 0.11 12.5 0.0 0.99 9.6 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Cys_Met_Meta_PP PF01053.20 KKK15656.1 - 2.5e-31 108.6 0.0 3.2e-31 108.2 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Nrap_D4 PF17405.2 KKK15657.1 - 5.8e-63 212.1 0.0 9.5e-63 211.4 0.0 1.3 1 0 0 1 1 1 1 Nrap protein nucleotidyltransferase domain 4 Nrap_D5 PF17406.2 KKK15657.1 - 3.6e-56 189.4 0.0 6.8e-56 188.5 0.0 1.5 1 0 0 1 1 1 1 Nrap protein PAP/OAS1-like domain 5 Nrap_D2 PF17403.2 KKK15657.1 - 4.4e-50 169.4 0.0 1.3e-47 161.4 0.0 2.5 2 0 0 2 2 2 2 Nrap protein PAP/OAS-like domain Nrap_D3 PF17404.2 KKK15657.1 - 2.9e-45 154.2 0.0 5.9e-45 153.2 0.0 1.5 1 0 0 1 1 1 1 Nrap protein domain 3 Nrap PF03813.14 KKK15657.1 - 9.7e-44 149.1 0.0 1.9e-43 148.1 0.0 1.5 1 0 0 1 1 1 1 Nrap protein domain 1 Nrap_D6 PF17407.2 KKK15657.1 - 3.4e-30 105.0 0.0 7.4e-30 103.9 0.0 1.6 1 0 0 1 1 1 1 Nrap protein domain 6 PAP_central PF04928.17 KKK15657.1 - 0.011 14.7 0.0 0.073 12.0 0.1 2.1 2 0 0 2 2 2 0 Poly(A) polymerase central domain MRP-L20 PF12824.7 KKK15658.1 - 2.1e-64 216.6 8.0 2.4e-64 216.4 8.0 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Peptidase_M20 PF01546.28 KKK15659.1 - 2.2e-31 109.2 0.0 2.8e-31 108.9 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KKK15659.1 - 1.8e-12 47.1 0.0 3.3e-12 46.3 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KKK15659.1 - 0.024 14.3 0.0 0.047 13.4 0.0 1.5 1 0 0 1 1 1 0 Peptidase family M28 SMC_N PF02463.19 KKK15660.1 - 4.1e-21 75.4 18.8 1.3e-12 47.6 0.2 3.1 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KKK15660.1 - 1.4e-14 55.1 21.8 1.4e-14 55.1 21.8 5.0 2 2 1 3 3 3 1 AAA domain AAA_15 PF13175.6 KKK15660.1 - 1.9e-07 31.2 18.0 1.9e-07 31.2 18.0 3.5 2 2 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 KKK15660.1 - 4.7e-07 29.9 6.6 7.3e-05 22.7 0.4 3.6 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system Spc7 PF08317.11 KKK15660.1 - 5e-06 25.6 19.4 5e-06 25.6 19.4 4.7 2 2 2 4 4 4 2 Spc7 kinetochore protein AAA_29 PF13555.6 KKK15660.1 - 0.00012 21.8 0.0 0.00026 20.7 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain YabA PF06156.13 KKK15660.1 - 0.016 15.9 6.8 0.016 15.9 6.8 6.4 4 2 2 6 6 6 0 Initiation control protein YabA SMC_hinge PF06470.13 KKK15660.1 - 0.036 14.4 0.0 0.2 11.9 0.0 2.4 2 0 0 2 2 2 0 SMC proteins Flexible Hinge Domain ABC_tran PF00005.27 KKK15660.1 - 0.13 12.8 0.1 0.13 12.8 0.1 6.1 3 2 0 3 3 3 0 ABC transporter Mito_carr PF00153.27 KKK15662.1 - 1.2e-48 163.0 4.5 2.6e-19 68.9 0.2 4.0 4 0 0 4 4 4 4 Mitochondrial carrier protein DEAD PF00270.29 KKK15663.1 - 5.3e-42 143.6 0.0 7.5e-42 143.1 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KKK15663.1 - 5.1e-28 97.6 0.7 7.7e-27 93.8 0.5 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KKK15663.1 - 0.012 15.7 0.0 0.024 14.6 0.0 1.5 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit DnaJ PF00226.31 KKK15664.1 - 7.5e-23 80.4 4.1 1.3e-22 79.6 2.2 2.5 2 0 0 2 2 2 1 DnaJ domain TPR_1 PF00515.28 KKK15664.1 - 3.5e-14 51.9 0.3 2.7e-06 26.9 0.0 6.5 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_2 PF07719.17 KKK15664.1 - 1.1e-13 50.2 0.8 0.00069 19.5 0.0 7.1 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_9 PF13371.6 KKK15664.1 - 1.5e-12 47.4 3.8 5.1e-06 26.5 0.8 4.6 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 KKK15664.1 - 1.2e-10 41.8 3.7 7.2e-06 26.4 0.1 4.2 4 1 1 5 5 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 KKK15664.1 - 3.6e-10 39.8 7.5 0.022 15.5 0.6 6.2 3 3 4 7 7 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 KKK15664.1 - 6.5e-09 35.3 0.9 0.16 12.2 0.0 7.1 8 0 0 8 8 7 1 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 KKK15664.1 - 9.7e-07 28.5 1.5 0.0026 17.4 0.1 2.6 2 0 0 2 2 2 2 Bacterial type III secretion protein (HrpB1_HrpK) TPR_16 PF13432.6 KKK15664.1 - 1.7e-06 28.6 11.0 0.019 15.6 0.0 4.8 6 0 0 6 6 4 2 Tetratricopeptide repeat PknG_TPR PF16918.5 KKK15664.1 - 0.00019 20.3 0.1 0.027 13.2 0.0 2.8 2 1 1 3 3 3 1 Protein kinase G tetratricopeptide repeat TPR_6 PF13174.6 KKK15664.1 - 0.0002 21.8 11.1 4.6 8.1 0.0 7.6 9 0 0 9 9 7 1 Tetratricopeptide repeat TPR_7 PF13176.6 KKK15664.1 - 0.00042 20.1 0.7 1.3 9.2 0.0 4.6 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 KKK15664.1 - 0.00056 20.2 1.0 7.5 6.9 0.0 4.4 4 1 0 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KKK15664.1 - 0.0013 18.9 9.2 0.01 16.1 0.1 4.8 3 2 2 6 6 6 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 KKK15664.1 - 0.0028 17.3 2.5 0.03 14.0 0.0 4.1 6 1 0 6 6 6 1 TPR repeat TPR_17 PF13431.6 KKK15664.1 - 0.0089 16.3 5.2 0.3 11.6 0.0 4.2 5 0 0 5 5 3 1 Tetratricopeptide repeat PNMA PF14893.6 KKK15664.1 - 2 7.7 8.0 5 6.4 1.1 2.6 1 1 2 3 3 3 0 PNMA PCRF PF03462.18 KKK15665.1 - 4.1e-51 173.6 0.0 3.5e-50 170.6 0.0 2.0 2 0 0 2 2 2 1 PCRF domain RF-1 PF00472.20 KKK15665.1 - 1.4e-34 118.5 1.4 1.4e-34 118.5 1.4 2.1 2 0 0 2 2 2 1 RF-1 domain Syntaxin_2 PF14523.6 KKK15665.1 - 0.055 13.8 2.2 0.064 13.6 0.3 2.0 2 0 0 2 2 2 0 Syntaxin-like protein Pas_Saposin PF09016.10 KKK15665.1 - 0.15 12.4 0.0 0.32 11.4 0.0 1.5 1 0 0 1 1 1 0 Pas factor saposin fold BST2 PF16716.5 KKK15665.1 - 0.66 10.6 4.1 1.3 9.7 0.6 2.4 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 Aldo_ket_red PF00248.21 KKK15682.1 - 2.8e-28 99.0 0.0 9.6e-17 61.1 0.0 3.0 1 1 1 2 2 2 2 Aldo/keto reductase family Sulfotransfer_3 PF13469.6 KKK15683.1 - 0.028 14.8 0.2 0.83 10.0 0.0 2.5 3 0 0 3 3 3 0 Sulfotransferase family MFS_1 PF07690.16 KKK15684.1 - 5.9e-31 107.7 29.3 7.6e-31 107.3 29.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.20 KKK15684.1 - 1.8e-06 26.6 5.3 6.5e-06 24.7 5.0 1.8 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family Sugar_tr PF00083.24 KKK15684.1 - 1.5e-05 24.1 8.1 1.5e-05 24.1 8.1 1.9 2 0 0 2 2 2 1 Sugar (and other) transporter EptA_B_N PF08019.12 KKK15684.1 - 0.0022 17.9 3.6 0.013 15.4 1.3 2.5 2 0 0 2 2 2 1 Phosphoethanolamine transferase EptA/EptB LacY_symp PF01306.19 KKK15684.1 - 0.022 13.6 0.9 0.022 13.6 0.9 1.8 2 0 0 2 2 2 0 LacY proton/sugar symporter MFS_1_like PF12832.7 KKK15684.1 - 0.33 9.8 10.5 0.84 8.4 10.5 1.7 1 1 0 1 1 1 0 MFS_1 like family AMP-binding PF00501.28 KKK15686.1 - 2.3e-68 230.7 0.0 4.1e-68 229.9 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 KKK15686.1 - 6.4e-37 127.1 0.0 2e-36 125.5 0.0 1.9 1 1 0 1 1 1 1 Male sterility protein Condensation PF00668.20 KKK15686.1 - 1.3e-33 116.4 0.0 2.6e-33 115.4 0.0 1.5 1 0 0 1 1 1 1 Condensation domain Epimerase PF01370.21 KKK15686.1 - 9.6e-12 44.9 0.0 1.9e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 KKK15686.1 - 2.6e-10 40.5 0.0 7.5e-09 35.8 0.0 3.1 2 0 0 2 2 2 1 Phosphopantetheine attachment site Semialdhyde_dh PF01118.24 KKK15686.1 - 0.00037 20.9 0.0 0.00092 19.6 0.0 1.7 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 KKK15686.1 - 0.0011 18.0 0.0 0.0022 17.1 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 KKK15686.1 - 0.025 13.7 0.0 0.095 11.8 0.0 2.0 1 1 0 1 1 1 0 RmlD substrate binding domain AMP-binding_C PF13193.6 KKK15686.1 - 0.3 12.1 6.5 0.12 13.4 0.4 3.2 3 0 0 3 3 3 0 AMP-binding enzyme C-terminal domain 2OG-FeII_Oxy PF03171.20 KKK15687.1 - 2.9e-13 50.2 0.0 1.4e-12 48.0 0.0 1.9 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 KKK15687.1 - 3.1e-07 31.2 0.0 5.1e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Methyltransf_23 PF13489.6 KKK15696.1 - 1.2e-16 61.0 0.0 1.5e-16 60.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKK15696.1 - 2.4e-13 50.6 0.0 5e-13 49.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KKK15696.1 - 3.2e-13 50.1 0.0 6.1e-13 49.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KKK15696.1 - 2.6e-10 40.9 0.0 4.1e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KKK15696.1 - 4.2e-10 39.6 0.0 7.3e-10 38.8 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KKK15696.1 - 2.4e-05 23.8 0.1 5.6e-05 22.6 0.0 1.6 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family tRNA_U5-meth_tr PF05958.11 KKK15696.1 - 0.0034 16.4 0.0 0.0049 15.9 0.0 1.2 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Pox_MCEL PF03291.16 KKK15696.1 - 0.015 14.4 0.0 0.018 14.1 0.0 1.2 1 0 0 1 1 1 0 mRNA capping enzyme CheR PF01739.18 KKK15696.1 - 0.13 11.7 0.0 2.6 7.5 0.0 2.2 2 0 0 2 2 2 0 CheR methyltransferase, SAM binding domain Epimerase PF01370.21 KKK15697.1 - 5.4e-16 58.8 0.1 1.8e-15 57.1 0.0 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KKK15697.1 - 3e-15 56.4 0.0 4.3e-15 55.9 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KKK15697.1 - 2.8e-14 53.4 0.0 5.4e-14 52.5 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KKK15697.1 - 3.1e-12 46.1 0.1 6.2e-12 45.1 0.1 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KKK15697.1 - 1.3e-09 37.9 0.3 6.4e-09 35.6 0.1 1.9 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 KKK15697.1 - 2e-05 23.8 0.0 0.00026 20.2 0.0 2.4 1 1 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.25 KKK15697.1 - 3.3e-05 23.4 0.0 6.8e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.12 KKK15697.1 - 0.00014 21.2 0.3 0.0094 15.1 0.3 2.3 1 1 0 1 1 1 1 Male sterility protein adh_short_C2 PF13561.6 KKK15697.1 - 0.0056 16.3 0.0 0.0088 15.6 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.15 KKK15697.1 - 0.014 14.6 0.0 0.023 13.9 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein KR PF08659.10 KKK15697.1 - 0.015 15.3 0.0 2.7 7.9 0.0 2.3 2 0 0 2 2 2 0 KR domain DDE_Tnp_1_3 PF13612.6 KKK15697.1 - 0.16 12.0 0.0 0.34 10.9 0.0 1.6 2 0 0 2 2 2 0 Transposase DDE domain WW PF00397.26 KKK15698.1 - 8e-07 29.0 3.6 8e-07 29.0 3.6 1.9 2 0 0 2 2 2 1 WW domain SARAF PF06682.12 KKK15698.1 - 0.092 12.4 7.2 0.12 12.0 7.2 1.2 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis Pex14_N PF04695.13 KKK15698.1 - 0.1 13.2 3.1 0.16 12.6 3.1 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Spt20 PF12090.8 KKK15698.1 - 1.9 8.1 8.5 2.7 7.5 8.5 1.1 1 0 0 1 1 1 0 Spt20 family DUF2076 PF09849.9 KKK15698.1 - 2.6 8.0 20.1 7.8 6.5 20.1 1.8 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) SNARE PF05739.19 KKK15698.1 - 2.7 8.1 4.8 2 8.5 1.9 2.0 2 0 0 2 2 2 0 SNARE domain EspB PF05802.11 KKK15698.1 - 8.1 6.4 7.1 61 3.5 7.1 2.1 1 1 0 1 1 1 0 Enterobacterial EspB protein CoA_transf_3 PF02515.17 KKK15699.1 - 2e-67 227.9 0.0 6.2e-67 226.3 0.0 1.6 1 1 0 1 1 1 1 CoA-transferase family III Mito_carr PF00153.27 KKK15708.1 - 2.1e-66 219.9 2.7 1.3e-22 79.5 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein SBF_like PF13593.6 KKK15709.1 - 1.7e-84 283.8 20.8 2.4e-66 224.2 8.3 2.0 2 0 0 2 2 2 2 SBF-like CPA transporter family (DUF4137) SBF PF01758.16 KKK15709.1 - 5.1e-10 39.4 6.2 5.1e-10 39.4 6.2 2.1 2 0 0 2 2 2 1 Sodium Bile acid symporter family ADH_N PF08240.12 KKK15757.1 - 1.6e-09 37.6 0.0 2.8e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KKK15757.1 - 4.7e-06 26.6 0.0 1.2e-05 25.3 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 KKK15757.1 - 0.00047 20.0 0.0 0.00086 19.2 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase Aminotran_5 PF00266.19 KKK15758.1 - 3.6e-30 105.1 0.0 1.4e-19 70.3 0.0 2.0 1 1 1 2 2 2 2 Aminotransferase class-V ApbE PF02424.15 KKK15758.1 - 0.11 12.0 0.1 0.35 10.4 0.0 1.7 2 0 0 2 2 2 0 ApbE family Lipase_3 PF01764.25 KKK15760.1 - 1.5e-18 67.0 0.0 3e-18 66.0 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) DUF676 PF05057.14 KKK15760.1 - 0.11 11.9 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Peptidase_M7 PF02031.16 KKK15760.1 - 0.49 10.5 2.5 1.3 9.2 0.0 2.2 2 0 0 2 2 2 0 Streptomyces extracellular neutral proteinase (M7) family Pkinase PF00069.25 KKK15761.1 - 4.4e-67 226.2 0.0 5.7e-67 225.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK15761.1 - 1.8e-34 119.2 0.0 2.6e-34 118.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KKK15761.1 - 0.00013 21.4 0.0 0.00019 20.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KKK15761.1 - 0.0025 17.2 0.1 0.006 16.0 0.1 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KKK15761.1 - 0.0046 15.8 0.1 0.012 14.5 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase NmrA PF05368.13 KKK15762.1 - 3.5e-15 56.2 0.0 4.7e-15 55.8 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KKK15762.1 - 1.7e-14 54.1 0.0 5.6e-14 52.4 0.0 2.0 2 1 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 KKK15762.1 - 2.5e-09 37.0 0.1 5.7e-09 35.8 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KKK15762.1 - 1.7e-05 24.9 0.1 2.3e-05 24.4 0.1 1.2 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 KKK15762.1 - 3.6e-05 24.0 0.1 5.9e-05 23.3 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_4 PF07993.12 KKK15762.1 - 0.00048 19.4 0.0 0.00069 18.9 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Shikimate_DH PF01488.20 KKK15762.1 - 0.0058 16.7 0.1 0.01 15.9 0.1 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase GDP_Man_Dehyd PF16363.5 KKK15762.1 - 0.0067 15.9 0.0 0.032 13.6 0.1 1.9 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase CbiJ PF02571.14 KKK15762.1 - 0.0072 15.8 0.0 0.01 15.3 0.0 1.2 1 0 0 1 1 1 1 Precorrin-6x reductase CbiJ/CobK 3Beta_HSD PF01073.19 KKK15762.1 - 0.013 14.5 0.1 0.024 13.6 0.1 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 KKK15762.1 - 0.018 14.5 0.1 0.032 13.7 0.1 1.4 1 0 0 1 1 1 0 short chain dehydrogenase RmlD_sub_bind PF04321.17 KKK15762.1 - 0.027 13.6 0.1 0.044 12.9 0.1 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 KKK15762.1 - 0.031 13.4 0.3 0.071 12.2 0.3 1.5 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein TrkA_N PF02254.18 KKK15762.1 - 0.039 14.2 0.1 0.11 12.8 0.0 1.7 2 0 0 2 2 2 0 TrkA-N domain Semialdhyde_dh PF01118.24 KKK15762.1 - 0.068 13.6 0.1 0.16 12.4 0.1 1.7 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 KKK15762.1 - 0.21 11.7 0.6 0.44 10.7 0.5 1.6 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Zn_clus PF00172.18 KKK15763.1 - 0.0063 16.6 5.6 0.043 14.0 5.6 2.2 1 1 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PRK PF00485.18 KKK15764.1 - 1e-08 35.2 0.0 1.3e-08 34.9 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 KKK15764.1 - 3.1e-06 27.8 0.0 1e-05 26.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KKK15764.1 - 0.00014 22.3 0.6 0.00033 21.1 0.4 1.7 1 1 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.12 KKK15764.1 - 0.00022 20.6 0.5 0.00052 19.3 0.1 1.7 2 0 0 2 2 2 1 Zeta toxin AAA_22 PF13401.6 KKK15764.1 - 0.00067 19.9 0.0 0.006 16.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KKK15764.1 - 0.00077 19.6 3.3 0.048 13.8 3.3 2.8 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 KKK15764.1 - 0.001 18.8 0.2 1.2 8.8 0.0 2.2 2 0 0 2 2 2 2 Thymidylate kinase SRP54 PF00448.22 KKK15764.1 - 0.0028 17.3 0.0 0.0043 16.7 0.0 1.2 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA PF00004.29 KKK15764.1 - 0.0033 17.8 0.1 0.0078 16.6 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 KKK15764.1 - 0.019 14.7 0.2 0.034 13.9 0.2 1.3 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 KKK15764.1 - 0.019 14.2 0.0 0.034 13.3 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain MeaB PF03308.16 KKK15764.1 - 0.023 13.7 0.1 0.037 13.0 0.1 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_17 PF13207.6 KKK15764.1 - 0.03 14.7 0.1 0.68 10.4 0.1 2.4 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.20 KKK15764.1 - 0.035 14.0 0.1 0.19 11.6 0.0 2.0 2 0 0 2 2 2 0 Adenylylsulphate kinase 6PF2K PF01591.18 KKK15764.1 - 0.067 12.5 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase AAA_11 PF13086.6 KKK15764.1 - 0.15 11.8 0.0 0.19 11.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain SKI PF01202.22 KKK15764.1 - 0.33 11.1 1.5 12 6.0 0.1 2.3 2 0 0 2 2 2 0 Shikimate kinase IF-2B PF01008.17 KKK15765.1 - 6.2e-08 32.2 0.1 0.0019 17.5 0.0 2.3 2 0 0 2 2 2 2 Initiation factor 2 subunit family NUDIX PF00293.28 KKK15765.1 - 2.9e-05 24.1 0.1 7.1e-05 22.9 0.1 1.6 1 0 0 1 1 1 1 NUDIX domain Fungal_trans PF04082.18 KKK15766.1 - 1e-15 57.5 0.1 2.7e-15 56.1 0.0 1.6 1 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK15766.1 - 6.2e-08 32.6 6.7 1e-07 31.9 6.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Methyltransf_23 PF13489.6 KKK15767.1 - 7.8e-19 68.1 0.0 1.1e-18 67.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KKK15767.1 - 1.7e-16 60.7 0.0 3e-16 60.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKK15767.1 - 2.7e-13 50.4 0.0 4.9e-12 46.4 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KKK15767.1 - 3.5e-13 50.0 0.0 2.4e-12 47.3 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KKK15767.1 - 2.3e-10 40.5 0.0 6.9e-10 38.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain NodS PF05401.11 KKK15767.1 - 0.00058 19.5 0.0 0.022 14.4 0.0 2.2 2 0 0 2 2 2 1 Nodulation protein S (NodS) DREV PF05219.12 KKK15767.1 - 0.00092 18.4 0.0 0.0012 18.0 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase Ubie_methyltran PF01209.18 KKK15767.1 - 0.0027 17.1 0.0 0.25 10.6 0.0 2.2 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family RrnaAD PF00398.20 KKK15767.1 - 0.0045 16.1 0.0 0.0066 15.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_16 PF10294.9 KKK15767.1 - 0.019 14.7 0.0 0.06 13.1 0.0 1.8 2 0 0 2 2 2 0 Lysine methyltransferase MTS PF05175.14 KKK15767.1 - 0.086 12.4 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain PCMT PF01135.19 KKK15767.1 - 0.11 12.2 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.13 KKK15767.1 - 0.14 11.5 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.6 KKK15767.1 - 0.17 11.9 0.0 0.24 11.4 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_2 PF00891.18 KKK15769.1 - 2.1e-12 46.8 0.0 2.5e-12 46.6 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase domain Peptidase_M41 PF01434.18 KKK15771.1 - 3.8e-65 219.3 0.0 4.7e-65 219.0 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M41 DUF1295 PF06966.12 KKK15772.1 - 2.6e-42 144.9 6.2 3.3e-42 144.6 6.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Topoisom_bac PF01131.20 KKK15773.1 - 9.2e-100 334.5 0.0 1.7e-99 333.7 0.0 1.4 2 0 0 2 2 2 1 DNA topoisomerase Toprim PF01751.22 KKK15773.1 - 2.4e-19 69.5 0.0 9.4e-19 67.5 0.0 2.0 2 0 0 2 2 2 1 Toprim domain DUF4149 PF13664.6 KKK15774.1 - 9.6e-22 77.2 4.9 2.5e-21 75.9 2.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) Rab15_effector PF15208.6 KKK15774.1 - 0.12 11.6 0.0 0.16 11.2 0.0 1.1 1 0 0 1 1 1 0 Rab15 effector Ras PF00071.22 KKK15790.1 - 5.4e-60 201.7 0.2 6.4e-60 201.4 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KKK15790.1 - 1.8e-20 73.3 0.0 2.7e-20 72.8 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKK15790.1 - 1.5e-08 34.3 0.0 1.7e-08 34.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KKK15790.1 - 1.8e-06 27.6 0.1 1e-05 25.2 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KKK15790.1 - 6.1e-05 23.0 0.7 0.18 11.7 0.0 2.3 1 1 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 KKK15790.1 - 0.0021 17.6 0.0 0.0034 16.9 0.0 1.3 1 1 0 1 1 1 1 Ferrous iron transport protein B MMR_HSR1 PF01926.23 KKK15790.1 - 0.0021 18.1 0.0 0.0033 17.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase MMR_HSR1_Xtn PF16897.5 KKK15790.1 - 0.0057 16.7 0.0 0.011 15.7 0.0 1.6 1 1 0 1 1 1 1 C-terminal region of MMR_HSR1 domain ATP_bind_1 PF03029.17 KKK15790.1 - 0.15 11.8 1.7 1.9 8.2 0.1 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein IstB_IS21 PF01695.17 KKK15790.1 - 0.18 11.5 0.8 2.6 7.7 0.1 2.2 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF2075 PF09848.9 KKK15790.1 - 0.21 10.8 0.7 10 5.2 0.0 2.0 1 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) CbiA PF01656.23 KKK15790.1 - 0.22 11.6 0.6 0.93 9.6 0.6 2.0 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Glyco_hydro_16 PF00722.21 KKK15791.1 - 2.4e-43 147.7 5.3 2.4e-43 147.7 5.3 2.3 3 0 0 3 3 3 1 Glycosyl hydrolases family 16 Mif2_N PF15624.6 KKK15807.1 - 6.9e-34 117.4 4.0 6.9e-34 117.4 4.0 3.6 2 1 0 3 3 3 1 Kinetochore CENP-C fungal homologue, Mif2, N-terminal CENP-C_C PF11699.8 KKK15807.1 - 1.3e-22 79.8 8.1 1.7e-22 79.4 1.3 2.6 2 1 0 2 2 2 1 Mif2/CENP-C like CAP_GLY PF01302.25 KKK15808.1 - 1.1e-25 89.4 0.0 1.7e-25 88.8 0.0 1.3 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.6 KKK15808.1 - 1.2e-16 60.9 0.0 2.2e-16 60.1 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin-like domain ubiquitin PF00240.23 KKK15808.1 - 0.00043 20.0 0.0 0.001 18.8 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin family Aldedh PF00171.22 KKK15810.1 - 2.4e-34 118.7 0.0 2.7e-34 118.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Amino_oxidase PF01593.24 KKK15811.1 - 7.4e-54 183.7 0.1 9.1e-54 183.4 0.1 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Ribonuc_L-PSP PF01042.21 KKK15811.1 - 1.1e-16 60.9 0.0 2.3e-16 59.9 0.0 1.5 1 0 0 1 1 1 1 Endoribonuclease L-PSP NAD_binding_8 PF13450.6 KKK15811.1 - 3.1e-13 49.8 0.1 7.6e-13 48.5 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KKK15811.1 - 7.1e-09 35.2 0.7 1.1e-08 34.6 0.7 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 KKK15811.1 - 6.6e-07 29.0 0.7 9.6e-07 28.5 0.7 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.24 KKK15811.1 - 1.3e-06 28.3 0.8 3.6e-06 26.8 0.7 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 KKK15811.1 - 1.5e-06 27.6 0.3 2.9e-06 26.7 0.3 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.19 KKK15811.1 - 2.6e-06 26.9 0.3 6.6e-06 25.6 0.3 1.6 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 KKK15811.1 - 7.8e-06 25.2 0.6 1.4e-05 24.4 0.6 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KKK15811.1 - 0.00012 21.4 0.1 0.00029 20.2 0.1 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KKK15811.1 - 0.00058 18.7 0.2 0.00097 17.9 0.2 1.3 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.22 KKK15811.1 - 0.002 17.3 0.3 0.003 16.7 0.3 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 KKK15811.1 - 0.0052 16.1 0.1 0.012 14.9 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KKK15811.1 - 0.0088 16.6 0.1 0.02 15.4 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KKK15811.1 - 0.025 13.9 0.2 0.046 13.0 0.2 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Sugar_tr PF00083.24 KKK15816.1 - 3.6e-98 329.4 26.5 4.4e-98 329.1 26.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKK15816.1 - 2.8e-27 95.6 58.2 1.5e-24 86.6 29.7 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KKK15816.1 - 0.0038 15.8 1.9 0.0038 15.8 1.9 3.0 3 1 0 3 3 3 2 MFS/sugar transport protein Trp_oprn_chp PF09534.10 KKK15816.1 - 0.027 14.3 5.5 0.079 12.7 1.1 2.6 2 1 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF1230 PF06799.11 KKK15816.1 - 0.57 10.3 3.5 12 6.0 0.2 2.6 2 0 0 2 2 2 0 Conserved in the green lineage and diatoms 27 Gp_dh_N PF00044.24 KKK15817.1 - 1.7e-32 111.8 0.2 3.2e-32 110.9 0.1 1.5 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Gp_dh_C PF02800.20 KKK15817.1 - 2.4e-30 105.2 0.2 3.9e-30 104.5 0.2 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 2-Hacid_dh_C PF02826.19 KKK15817.1 - 0.0019 17.6 0.0 0.0032 16.9 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DapB_N PF01113.20 KKK15817.1 - 0.0025 17.9 0.0 0.0042 17.2 0.0 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus COesterase PF00135.28 KKK15819.1 - 2.5e-66 224.6 0.0 3.8e-66 224.0 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KKK15819.1 - 1.7e-06 28.1 0.1 1.1e-05 25.4 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold PCYCGC PF13798.6 KKK15819.1 - 0.1 12.4 0.1 0.17 11.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function with PCYCGC motif WD40 PF00400.32 KKK15821.1 - 1.7e-12 47.6 18.9 0.007 17.2 0.7 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.11 KKK15821.1 - 0.0011 18.9 0.0 0.0079 16.1 0.0 1.9 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Ccdc124 PF06244.12 KKK15822.1 - 9.1e-31 107.1 17.3 1.7e-29 103.0 17.3 2.1 1 1 0 1 1 1 1 Coiled-coil domain-containing protein 124 /Oxs1 Presenilin PF01080.17 KKK15822.1 - 6.5 5.4 7.2 6.1 5.5 7.2 1.2 1 0 0 1 1 1 0 Presenilin Pkinase PF00069.25 KKK15823.1 - 2.4e-64 217.3 0.0 3.9e-64 216.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK15823.1 - 1e-35 123.3 0.0 2.9e-30 105.4 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KKK15823.1 - 9.6e-07 28.4 0.1 0.0013 18.2 0.0 2.2 1 1 1 2 2 2 2 Kinase-like APH PF01636.23 KKK15823.1 - 0.00013 22.0 0.1 0.00047 20.2 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 KKK15823.1 - 0.0017 18.0 0.0 0.0035 16.9 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 KKK15823.1 - 0.012 14.6 0.1 0.021 13.8 0.1 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 KKK15823.1 - 0.024 14.0 0.2 0.056 12.8 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family MMM1 PF10296.9 KKK15824.1 - 6.8e-06 25.4 0.0 1.4e-05 24.3 0.0 1.5 1 1 0 1 1 1 1 Maintenance of mitochondrial morphology protein 1 GWT1 PF06423.12 KKK15825.1 - 1.4e-36 125.8 2.7 1.4e-36 125.8 2.7 2.0 2 1 0 2 2 2 1 GWT1 DUF4818 PF16089.5 KKK15825.1 - 0.023 15.1 1.8 0.074 13.5 0.0 2.8 2 1 0 3 3 3 0 Domain of unknown function (DUF4818) bZIP_1 PF00170.21 KKK15826.1 - 0.0014 18.7 10.0 0.0055 16.8 10.0 1.9 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KKK15826.1 - 0.11 12.6 13.1 7.8 6.7 13.0 2.3 1 1 0 1 1 1 0 Basic region leucine zipper Hydin_ADK PF17213.3 KKK15826.1 - 4 7.7 5.8 6.9 6.9 5.8 1.5 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain Acyl-CoA_dh_1 PF00441.24 KKK15827.1 - 3.5e-38 131.2 7.8 5.9e-38 130.4 7.8 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KKK15827.1 - 2.3e-27 95.9 1.0 6.6e-27 94.4 0.0 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KKK15827.1 - 5.7e-24 84.2 0.0 1.2e-23 83.1 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KKK15827.1 - 1.1e-16 61.4 4.3 2e-16 60.5 4.3 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Metallophos PF00149.28 KKK15827.1 - 1.5e-08 35.4 0.3 2.7e-08 34.6 0.3 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase HpaB_N PF11794.8 KKK15827.1 - 0.024 14.3 0.0 0.062 12.9 0.0 1.7 1 0 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal Senescence PF06911.12 KKK15828.1 - 1e-53 182.4 3.2 1.5e-53 181.8 3.2 1.3 1 0 0 1 1 1 1 Senescence-associated protein DUF3082 PF11282.8 KKK15828.1 - 0.037 14.3 0.0 0.09 13.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3082) Atx10homo_assoc PF09759.9 KKK15832.1 - 1.7e-33 114.6 0.5 4e-33 113.4 0.1 1.8 2 0 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain RNA_pol_3_Rpc31 PF11705.8 KKK15832.1 - 0.1 12.9 6.4 0.2 11.9 6.4 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 DHHC PF01529.20 KKK15832.1 - 0.11 12.6 0.2 0.22 11.6 0.2 1.5 1 0 0 1 1 1 0 DHHC palmitoyltransferase SLAIN PF15301.6 KKK15832.1 - 0.12 11.6 2.4 0.21 10.8 2.4 1.3 1 0 0 1 1 1 0 SLAIN motif-containing family zf-RING_2 PF13639.6 KKK15833.1 - 2.2e-08 34.3 2.4 4.4e-08 33.3 2.4 1.5 1 0 0 1 1 1 1 Ring finger domain Putative_PNPOx PF01243.20 KKK15833.1 - 2.4e-08 34.0 0.0 2.7e-05 24.3 0.0 3.1 2 1 0 2 2 2 2 Pyridoxamine 5'-phosphate oxidase zf-rbx1 PF12678.7 KKK15833.1 - 3.5e-05 24.0 3.3 7.4e-05 23.0 2.2 2.1 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KKK15833.1 - 0.0014 18.6 5.5 0.0029 17.6 5.5 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 KKK15833.1 - 0.0019 18.2 0.4 0.0036 17.3 0.4 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.6 KKK15833.1 - 0.012 15.4 2.9 0.024 14.5 2.1 2.0 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KKK15833.1 - 0.013 15.3 1.4 0.025 14.3 1.4 1.5 1 0 0 1 1 1 0 RING-like zinc finger FAD_binding_6 PF00970.24 KKK15833.1 - 0.015 15.6 0.0 0.042 14.2 0.0 1.7 1 1 0 1 1 1 0 Oxidoreductase FAD-binding domain Kdo PF06293.14 KKK15834.1 - 5.4e-05 22.6 0.0 0.00014 21.3 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 KKK15834.1 - 0.0025 17.5 0.2 0.0076 15.9 0.0 1.8 2 0 0 2 2 2 1 Choline/ethanolamine kinase Pkinase PF00069.25 KKK15834.1 - 0.0027 17.1 0.0 0.0064 15.9 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KKK15834.1 - 0.0038 17.2 0.1 0.0038 17.2 0.1 3.1 2 1 1 3 3 3 1 Phosphotransferase enzyme family DUF390 PF04094.14 KKK15834.1 - 0.012 14.0 3.6 0.019 13.3 3.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF390) ACOX PF01756.19 KKK15834.1 - 0.068 12.7 0.2 0.13 11.8 0.2 1.4 1 0 0 1 1 1 0 Acyl-CoA oxidase Peptidase_C6 PF00851.18 KKK15834.1 - 0.15 10.9 0.0 0.27 10.1 0.0 1.3 1 0 0 1 1 1 0 Helper component proteinase ORC_WH_C PF18137.1 KKK15834.1 - 0.89 9.6 5.0 2.5 8.2 5.0 1.7 1 0 0 1 1 1 0 Origin recognition complex winged helix C-terminal tRNA-synt_2 PF00152.20 KKK15835.1 - 6.9e-78 261.9 0.2 9.8e-78 261.4 0.2 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KKK15835.1 - 1.6e-13 50.4 0.1 3.6e-13 49.3 0.1 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 KKK15835.1 - 3.8e-05 23.3 0.0 0.041 13.4 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) SWIRM PF04433.17 KKK15835.1 - 0.1 12.9 1.2 0.57 10.5 0.5 2.4 2 0 0 2 2 2 0 SWIRM domain Dynamin_M PF01031.20 KKK15836.1 - 4.7e-28 98.2 0.0 2.4e-19 69.6 0.0 2.3 2 0 0 2 2 2 2 Dynamin central region Dynamin_N PF00350.23 KKK15836.1 - 4.8e-24 85.3 0.0 1e-23 84.2 0.0 1.6 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 KKK15836.1 - 4.3e-05 23.6 1.1 0.00011 22.3 0.2 2.2 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 KKK15836.1 - 0.0049 16.9 0.0 0.029 14.5 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase FRB_dom PF08771.11 KKK15836.1 - 0.037 14.4 4.9 0.4 11.1 0.5 2.8 3 0 0 3 3 3 0 FKBP12-rapamycin binding domain IIGP PF05049.13 KKK15836.1 - 0.043 12.9 0.0 4.8 6.1 0.0 2.3 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) CM_1 PF07736.11 KKK15836.1 - 0.05 14.0 0.2 1.1 9.7 0.0 2.6 3 0 0 3 3 3 0 Chorismate mutase type I Roc PF08477.13 KKK15836.1 - 0.074 13.3 0.0 0.3 11.3 0.0 2.0 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 KKK15836.1 - 0.17 12.3 0.0 1.3 9.3 0.0 2.6 2 0 0 2 2 2 0 AAA ATPase domain Cpn60_TCP1 PF00118.24 KKK15837.1 - 1.5e-158 528.5 2.9 1.7e-158 528.3 2.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Chromo_shadow PF01393.19 KKK15838.1 - 3.8e-19 68.5 0.1 1.8e-16 59.9 0.1 2.3 2 0 0 2 2 2 2 Chromo shadow domain Chromo PF00385.24 KKK15838.1 - 2e-10 40.4 0.8 2e-09 37.2 0.1 2.4 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain ORC6 PF05460.13 KKK15838.1 - 0.00056 19.3 3.2 0.00073 18.9 3.2 1.2 1 0 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) DUF908 PF06012.12 KKK15838.1 - 0.22 10.9 0.9 0.28 10.5 0.9 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Myb_DNA-bind_2 PF08914.11 KKK15839.1 - 1.9e-22 79.2 1.1 4.9e-22 77.9 1.1 1.8 1 0 0 1 1 1 1 Rap1 Myb domain Rap1_C PF11626.8 KKK15839.1 - 3.1e-22 78.4 0.0 9.2e-22 76.9 0.0 1.8 1 0 0 1 1 1 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain BRCT_2 PF16589.5 KKK15839.1 - 6.7e-12 45.7 0.0 1.7e-11 44.3 0.0 1.7 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain Rap1-DNA-bind PF09197.10 KKK15839.1 - 1.1e-05 25.9 0.1 6.2e-05 23.6 0.1 2.2 2 1 0 2 2 2 1 Rap1, DNA-binding Ndc1_Nup PF09531.10 KKK15839.1 - 3.6 6.2 4.5 4.5 5.8 4.5 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SWIRM-assoc_2 PF16496.5 KKK15839.1 - 5.8 5.7 9.2 12 4.6 9.2 1.5 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal DUF2070 PF09843.9 KKK15840.1 - 3.4 5.9 16.8 4.5 5.4 16.8 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) NTP_transferase PF00483.23 KKK15841.1 - 9.4e-32 110.5 0.0 1.4e-31 110.0 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 KKK15841.1 - 5.5e-08 33.3 0.0 1e-07 32.5 0.0 1.5 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep PF00132.24 KKK15841.1 - 1.1e-07 31.3 8.0 1.4e-06 27.7 0.2 3.5 2 1 1 3 3 3 2 Bacterial transferase hexapeptide (six repeats) IspD PF01128.19 KKK15841.1 - 0.0034 17.2 0.0 0.0061 16.3 0.0 1.4 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Fucokinase PF07959.12 KKK15841.1 - 0.013 14.5 0.4 1.3 7.9 0.2 2.4 2 1 0 2 2 2 0 L-fucokinase Glycos_transf_2 PF00535.26 KKK15841.1 - 0.032 14.0 0.0 0.056 13.2 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 DUF2968 PF11180.8 KKK15841.1 - 0.16 11.6 0.1 0.25 10.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) CENP-L PF13092.6 KKK15854.1 - 1.5e-41 142.4 0.0 2.3e-41 141.7 0.0 1.3 1 0 0 1 1 1 1 Kinetochore complex Sim4 subunit Fta1 F-box-like PF12937.7 KKK15855.1 - 0.0002 21.2 0.1 0.0002 21.2 0.1 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KKK15855.1 - 0.00022 21.0 0.0 0.00061 19.6 0.0 1.8 1 0 0 1 1 1 1 F-box domain PRANC PF09372.10 KKK15855.1 - 0.011 16.0 0.0 0.17 12.2 0.0 2.5 2 0 0 2 2 2 0 PRANC domain FYVE PF01363.21 KKK15856.1 - 1.7e-22 79.4 23.1 3.2e-16 59.2 6.1 3.0 3 0 0 3 3 3 2 FYVE zinc finger Rbsn PF11464.8 KKK15856.1 - 5.5e-18 64.4 1.0 1.5e-17 63.0 1.0 1.8 1 0 0 1 1 1 1 Rabenosyn Rab binding domain YqaH PF17448.2 KKK15856.1 - 0.00034 20.9 0.2 0.001 19.3 0.2 1.8 1 0 0 1 1 1 1 Uncharacterized YqaH-like zf-AN1 PF01428.16 KKK15856.1 - 0.0021 18.2 6.1 0.0021 18.2 6.1 3.8 3 1 1 4 4 4 1 AN1-like Zinc finger zf-Di19 PF05605.12 KKK15856.1 - 0.027 14.8 13.3 0.11 12.8 0.1 3.0 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding Flagellin_N PF00669.20 KKK15856.1 - 0.034 14.3 0.5 0.29 11.2 0.0 2.5 2 0 0 2 2 2 0 Bacterial flagellin N-terminal helical region TMF_TATA_bd PF12325.8 KKK15856.1 - 0.05 13.8 0.2 0.05 13.8 0.2 2.7 4 0 0 4 4 4 0 TATA element modulatory factor 1 TATA binding zf-C2H2_4 PF13894.6 KKK15856.1 - 0.33 11.9 0.0 0.33 11.9 0.0 5.1 5 1 0 5 5 5 0 C2H2-type zinc finger UBZ_FAAP20 PF15750.5 KKK15856.1 - 2 8.4 4.8 13 5.9 0.7 3.1 3 0 0 3 3 3 0 Ubiquitin-binding zinc-finger IBR PF01485.21 KKK15856.1 - 2.8 8.2 19.4 0.14 12.4 3.7 3.4 4 0 0 4 4 3 0 IBR domain, a half RING-finger domain HypA PF01155.19 KKK15856.1 - 7.7 6.6 15.2 0.31 11.1 0.5 3.7 3 1 1 4 4 4 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA PKD_channel PF08016.12 KKK15857.1 - 2.7e-06 26.4 22.8 2.8e-05 23.0 22.7 2.2 1 1 0 1 1 1 1 Polycystin cation channel MADF_DNA_bdg PF10545.9 KKK15857.1 - 0.0085 16.4 1.5 0.44 10.9 1.5 2.6 1 1 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like E1-E2_ATPase PF00122.20 KKK15858.1 - 4.3e-18 65.5 0.0 1.1e-17 64.2 0.0 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 KKK15858.1 - 7.2e-14 52.6 2.3 1.8e-07 31.7 1.7 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KKK15858.1 - 0.0031 17.5 0.0 0.083 13.0 0.0 2.4 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KKK15858.1 - 0.017 14.8 0.1 0.07 12.9 0.0 1.9 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase S6PP PF05116.13 KKK15858.1 - 0.078 12.5 0.3 0.34 10.4 0.0 2.1 3 0 0 3 3 3 0 Sucrose-6F-phosphate phosphohydrolase GLTP PF08718.11 KKK15859.1 - 2.1e-45 154.7 0.0 2.8e-45 154.2 0.0 1.2 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) BMC PF00936.19 KKK15859.1 - 0.057 13.4 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 BMC domain PH_4 PF15404.6 KKK15860.1 - 2.9e-53 180.4 5.2 2.1e-52 177.6 1.2 3.5 3 1 0 3 3 3 1 Pleckstrin homology domain Spo7_2_N PF15407.6 KKK15860.1 - 4.4e-23 80.7 1.2 1.4e-22 79.1 1.2 2.0 1 0 0 1 1 1 1 Sporulation protein family 7 PH PF00169.29 KKK15860.1 - 1.6e-09 38.2 6.9 0.00014 22.3 0.0 5.9 5 1 0 5 5 5 2 PH domain PH_6 PF15406.6 KKK15860.1 - 0.0055 17.0 0.1 7.1 7.0 0.0 2.9 2 0 0 2 2 2 2 Pleckstrin homology domain PH_9 PF15410.6 KKK15860.1 - 0.07 13.5 0.3 0.71 10.2 0.1 2.7 2 0 0 2 2 2 0 Pleckstrin homology domain DUF1654 PF07867.11 KKK15860.1 - 0.12 12.2 0.2 0.49 10.2 0.2 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1654) DUF1992 PF09350.10 KKK15860.1 - 0.14 12.3 1.0 1.8 8.8 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF1992) Macro PF01661.21 KKK15861.1 - 5.6e-40 136.1 0.1 8.3e-40 135.5 0.1 1.2 1 0 0 1 1 1 1 Macro domain Peptidase_S24 PF00717.23 KKK15862.1 - 4e-05 23.5 0.0 0.0002 21.3 0.0 2.1 1 1 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 KKK15862.1 - 0.0017 18.2 0.0 0.54 10.0 0.0 2.3 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 GATA PF00320.27 KKK15863.1 - 3.5e-15 55.3 5.3 6.2e-15 54.5 5.3 1.4 1 0 0 1 1 1 1 GATA zinc finger zinc_ribbon_9 PF14369.6 KKK15863.1 - 0.43 10.9 1.6 0.91 9.8 1.6 1.5 1 0 0 1 1 1 0 zinc-ribbon adh_short PF00106.25 KKK15864.1 - 1.4e-12 47.5 0.0 1.9e-12 47.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KKK15864.1 - 3.9e-09 36.4 0.0 5e-09 36.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Band_7 PF01145.25 KKK15865.1 - 2.8e-28 99.1 3.3 2.8e-28 99.1 3.3 1.6 2 0 0 2 2 2 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 KKK15865.1 - 0.035 13.8 0.2 0.059 13.1 0.2 1.3 1 0 0 1 1 1 0 SPFH domain-Band 7 family EIF_2_alpha PF07541.12 KKK15866.1 - 6.5e-39 132.6 0.0 1.3e-38 131.6 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 KKK15866.1 - 8.3e-13 48.5 0.5 1.7e-12 47.5 0.5 1.6 1 0 0 1 1 1 1 S1 RNA binding domain Sulfate_transp PF00916.20 KKK15867.1 - 5.5e-78 262.4 14.0 7.6e-78 261.9 14.0 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 KKK15867.1 - 8.4e-16 57.7 0.0 1.4e-15 56.9 0.0 1.4 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 KKK15867.1 - 0.00023 21.4 0.0 0.00089 19.6 0.0 2.0 2 0 0 2 2 2 1 STAS domain MFS_MOT1 PF16983.5 KKK15867.1 - 0.0031 17.9 15.0 0.0033 17.8 3.8 2.8 2 1 0 2 2 2 2 Molybdate transporter of MFS superfamily Orf78 PF06024.12 KKK15867.1 - 0.22 11.8 0.8 0.58 10.5 0.1 2.1 2 0 0 2 2 2 0 Orf78 (ac78) GTP_EFTU PF00009.27 KKK15869.1 - 1.6e-35 122.5 0.0 7.2e-35 120.3 0.0 2.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 KKK15869.1 - 1.9e-19 69.7 0.1 6.2e-19 68.1 0.1 1.9 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.25 KKK15869.1 - 4.1e-11 43.1 2.5 1.2e-09 38.4 0.0 3.7 3 0 0 3 3 3 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.6 KKK15869.1 - 4.3e-08 33.0 0.1 1.5e-07 31.2 0.1 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.23 KKK15869.1 - 2e-06 27.9 0.2 2.3e-05 24.4 0.0 2.9 3 0 0 3 3 3 1 50S ribosome-binding GTPase Roc PF08477.13 KKK15869.1 - 0.0019 18.4 0.0 0.0057 16.9 0.0 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 KKK15869.1 - 0.013 15.3 0.0 0.042 13.6 0.0 2.0 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein RsgA_GTPase PF03193.16 KKK15869.1 - 0.046 13.6 0.2 0.6 10.0 0.2 2.8 2 1 0 2 2 2 0 RsgA GTPase Fe-ADH_2 PF13685.6 KKK15869.1 - 0.66 9.6 2.6 1.8 8.2 2.6 1.7 1 0 0 1 1 1 0 Iron-containing alcohol dehydrogenase Rhodanese PF00581.20 KKK15870.1 - 6.5e-10 39.5 0.0 1.1e-09 38.8 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain Yip1 PF04893.17 KKK15871.1 - 6.7e-15 55.2 14.7 9.5e-15 54.7 14.7 1.3 1 1 0 1 1 1 1 Yip1 domain YIF1 PF03878.15 KKK15871.1 - 0.069 12.7 3.2 0.38 10.2 3.2 2.1 1 1 0 1 1 1 0 YIF1 RabGAP-TBC PF00566.18 KKK15872.1 - 9.8e-23 80.9 0.2 1.4e-22 80.5 0.2 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain CaKB PF03185.15 KKK15872.1 - 0.1 12.3 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Calcium-activated potassium channel, beta subunit MMS1_N PF10433.9 KKK15873.1 - 1.9e-106 356.6 0.0 2.7e-106 356.1 0.0 1.3 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term p450 PF00067.22 KKK15874.1 - 1.4e-56 192.2 0.0 2e-56 191.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DNA_ligase_OB PF03120.16 KKK15874.1 - 0.23 11.4 0.0 0.49 10.3 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent DNA ligase OB-fold domain MarB PF13999.6 KKK15875.1 - 0.27 11.1 2.1 1.2 9.1 0.2 2.6 2 1 1 3 3 3 0 MarB protein NIF PF03031.18 KKK15886.1 - 1.3e-41 142.0 0.1 1.8e-41 141.5 0.1 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase JAB PF01398.21 KKK15887.1 - 5.1e-33 113.5 0.0 1.1e-32 112.5 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 KKK15887.1 - 1.2e-12 48.2 1.3 2.2e-12 47.4 1.3 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.6 KKK15887.1 - 1.2e-07 31.5 0.0 2.8e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Ribosomal_L14 PF00238.19 KKK15889.1 - 1.2e-34 119.1 0.0 1.3e-34 118.8 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Endonuc-FokI_C PF09254.11 KKK15889.1 - 0.13 11.5 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 Restriction endonuclease FokI, C terminal Hist_deacetyl PF00850.19 KKK15890.1 - 3.9e-82 276.2 0.0 7.3e-82 275.3 0.0 1.5 2 0 0 2 2 2 1 Histone deacetylase domain adh_short_C2 PF13561.6 KKK15897.1 - 3.7e-55 187.0 0.0 6e-55 186.4 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KKK15897.1 - 1.3e-38 132.5 0.0 1.8e-38 132.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KKK15897.1 - 4.7e-13 49.4 0.1 7.7e-13 48.7 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KKK15897.1 - 0.0066 15.9 0.1 0.012 15.1 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Pyr_redox_2 PF07992.14 KKK15897.1 - 0.013 14.7 0.0 0.02 14.1 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GDP_Man_Dehyd PF16363.5 KKK15897.1 - 0.016 14.6 0.1 1.6 8.1 0.0 2.1 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase DUF1752 PF08550.10 KKK15898.1 - 0.00013 21.7 0.1 0.00026 20.8 0.1 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) PRIMA1 PF16101.5 KKK15898.1 - 0.58 10.2 7.4 1.3 9.0 3.0 2.6 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 DUF963 PF06131.11 KKK15899.1 - 0.14 11.6 6.9 2.6 7.5 2.1 2.9 2 0 0 2 2 2 0 Schizosaccharomyces pombe repeat of unknown function (DUF963) CPSase_L_D2 PF02786.17 KKK15900.1 - 9.6e-75 250.7 0.0 1.4e-74 250.1 0.0 1.2 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.19 KKK15900.1 - 1e-36 125.3 0.0 2.6e-36 124.0 0.0 1.8 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_carb_N PF00289.22 KKK15900.1 - 4.2e-35 120.6 0.0 8.5e-35 119.6 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_lipoyl PF00364.22 KKK15900.1 - 2.4e-18 65.7 1.4 3.2e-17 62.1 0.9 2.8 2 0 0 2 2 2 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 KKK15900.1 - 1.2e-10 41.3 0.0 2.5e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 KKK15900.1 - 5.7e-09 35.8 0.0 1.1e-08 34.9 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.6 KKK15900.1 - 2.4e-05 24.1 0.2 0.076 12.8 0.1 2.8 1 1 1 2 2 2 2 Biotin-lipoyl like ATP-grasp_3 PF02655.14 KKK15900.1 - 5.9e-05 23.2 0.0 0.00013 22.1 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 KKK15900.1 - 0.0016 18.3 0.1 0.003 17.4 0.1 1.5 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATPgrasp_ST PF14397.6 KKK15900.1 - 0.0032 16.8 0.0 0.0061 15.9 0.0 1.4 1 0 0 1 1 1 1 Sugar-transfer associated ATP-grasp HlyD_3 PF13437.6 KKK15900.1 - 0.019 15.7 0.0 14 6.4 0.0 2.8 2 0 0 2 2 2 0 HlyD family secretion protein ATP-grasp_4 PF13535.6 KKK15900.1 - 0.035 13.7 0.0 0.071 12.7 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain RimK PF08443.11 KKK15900.1 - 0.046 13.3 0.0 0.15 11.7 0.0 1.8 2 0 0 2 2 2 0 RimK-like ATP-grasp domain GCV_H PF01597.19 KKK15900.1 - 0.05 13.5 0.1 0.12 12.3 0.1 1.6 1 0 0 1 1 1 0 Glycine cleavage H-protein RnfC_N PF13375.6 KKK15900.1 - 0.086 12.8 0.3 7.6 6.6 0.1 2.9 2 0 0 2 2 2 0 RnfC Barrel sandwich hybrid domain Carboxyl_trans PF01039.22 KKK15901.1 - 4.5e-128 428.0 0.0 7.2e-126 420.7 0.0 2.1 1 1 0 1 1 1 1 Carboxyl transferase domain adh_short_C2 PF13561.6 KKK15901.1 - 0.059 12.9 0.4 0.16 11.5 0.0 1.8 2 0 0 2 2 2 0 Enoyl-(Acyl carrier protein) reductase Acyl-CoA_dh_1 PF00441.24 KKK15902.1 - 1.6e-39 135.5 0.8 2.8e-39 134.7 0.8 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KKK15902.1 - 1.7e-32 112.4 0.1 3.1e-32 111.6 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KKK15902.1 - 3.4e-27 94.5 0.1 6.7e-27 93.5 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KKK15902.1 - 2.9e-13 50.3 0.1 5.7e-13 49.3 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 KKK15902.1 - 0.0037 17.0 0.1 0.013 15.1 0.1 1.9 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal DDOST_48kD PF03345.14 KKK15903.1 - 2.4e-160 534.0 0.0 2.8e-160 533.7 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta DUF11 PF01345.18 KKK15903.1 - 0.16 12.3 0.1 0.55 10.6 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function DUF11 Abhydrolase_1 PF00561.20 KKK15905.1 - 2e-25 89.9 0.0 3.3e-25 89.2 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydro_lipase PF04083.16 KKK15905.1 - 1e-22 79.4 0.1 2.4e-22 78.3 0.0 1.7 2 0 0 2 2 2 1 Partial alpha/beta-hydrolase lipase region Hydrolase_4 PF12146.8 KKK15905.1 - 1.5e-05 24.4 0.0 0.01 15.1 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 FSH1 PF03959.13 KKK15905.1 - 0.024 14.3 0.0 3.4 7.3 0.0 2.1 2 0 0 2 2 2 0 Serine hydrolase (FSH1) Pet191_N PF10203.9 KKK15906.1 - 3.6e-17 62.4 0.9 4.6e-17 62.1 0.9 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 Methyltransf_2 PF00891.18 KKK15907.1 - 1e-19 70.7 0.0 1.9e-19 69.8 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation2 PF16864.5 KKK15907.1 - 0.0057 16.6 0.0 0.015 15.3 0.0 1.7 1 0 0 1 1 1 1 Dimerisation domain Dimerisation PF08100.11 KKK15907.1 - 0.025 14.6 0.1 0.067 13.2 0.1 1.7 1 0 0 1 1 1 0 Dimerisation domain ketoacyl-synt PF00109.26 KKK15908.1 - 1e-72 244.8 0.0 2.5e-72 243.5 0.0 1.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain SAT PF16073.5 KKK15908.1 - 1.1e-44 153.0 0.0 5.4e-44 150.7 0.0 2.1 2 0 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Ketoacyl-synt_C PF02801.22 KKK15908.1 - 6.8e-36 122.9 3.2 2.8e-35 120.9 1.0 2.4 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.21 KKK15908.1 - 4.1e-31 108.7 0.2 7.4e-31 107.8 0.2 1.4 1 0 0 1 1 1 1 Acyl transferase domain KAsynt_C_assoc PF16197.5 KKK15908.1 - 1.9e-10 41.2 0.0 4.6e-10 39.9 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension PP-binding PF00550.25 KKK15908.1 - 3.3e-09 37.0 0.4 9.1e-09 35.5 0.4 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.23 KKK15908.1 - 0.027 13.8 0.3 0.06 12.7 0.3 1.5 1 0 0 1 1 1 0 Thiolase, N-terminal domain Raf1_HTH PF18579.1 KKK15908.1 - 0.068 12.9 0.0 0.22 11.3 0.0 1.9 1 0 0 1 1 1 0 Rubisco accumulation factor 1 helix turn helix domain SR-25 PF10500.9 KKK15908.1 - 6 6.4 7.9 6.2 6.4 1.9 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Sulfotransfer_3 PF13469.6 KKK15910.1 - 0.0044 17.4 0.1 0.013 15.9 0.1 1.8 1 1 0 1 1 1 1 Sulfotransferase family p450 PF00067.22 KKK15911.1 - 2e-22 79.6 0.1 2.8e-22 79.1 0.1 1.2 1 0 0 1 1 1 1 Cytochrome P450 DUF3991 PF13154.6 KKK15911.1 - 0.1 13.0 0.0 0.35 11.3 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3991) DUF4980 PF16352.5 KKK15911.1 - 0.12 12.4 0.1 0.4 10.7 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4980) Glyco_hydro_75 PF07335.11 KKK15912.1 - 6.9e-43 146.8 0.1 1.4e-42 145.8 0.0 1.5 2 0 0 2 2 2 1 Fungal chitosanase of glycosyl hydrolase group 75 Ras PF00071.22 KKK15913.1 - 5.9e-52 175.5 0.0 7.3e-52 175.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KKK15913.1 - 6.9e-19 68.2 0.0 1.1e-18 67.6 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKK15913.1 - 8e-10 38.4 0.0 9.9e-10 38.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KKK15913.1 - 1.5e-05 24.6 0.0 0.00015 21.4 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KKK15913.1 - 9.3e-05 22.5 0.0 0.00017 21.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KKK15913.1 - 0.0014 18.6 0.1 1.4 8.8 0.1 2.2 1 1 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 KKK15913.1 - 0.032 14.5 0.6 0.47 10.7 0.2 2.6 2 1 0 2 2 2 0 AAA domain Acetyltransf_1 PF00583.25 KKK15914.1 - 1.3e-10 41.5 0.0 1.6e-10 41.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KKK15914.1 - 5.6e-09 36.3 0.0 7.7e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KKK15914.1 - 4.2e-08 33.1 0.0 6e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 KKK15914.1 - 1.1e-07 31.8 0.0 1.2e-07 31.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.7 KKK15914.1 - 0.00062 19.9 0.0 0.00082 19.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KKK15914.1 - 0.0013 18.8 0.0 0.0022 18.1 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase PanZ PF12568.8 KKK15914.1 - 0.003 17.3 0.1 0.0039 16.9 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain, PanZ He_PIG PF05345.12 KKK15915.1 - 1.1e-14 54.3 10.0 0.00013 22.1 0.1 4.9 4 0 0 4 4 4 3 Putative Ig domain BACON PF13004.7 KKK15915.1 - 0.00014 21.8 4.7 0.34 10.9 0.3 3.9 3 0 0 3 3 3 3 Putative binding domain, N-terminal PMP1_2 PF08114.11 KKK15915.1 - 0.32 10.8 0.8 0.7 9.7 0.8 1.5 1 0 0 1 1 1 0 ATPase proteolipid family CUE PF02845.16 KKK15916.1 - 3.4e-10 39.4 0.0 5.8e-10 38.7 0.0 1.3 1 0 0 1 1 1 1 CUE domain MOZART1 PF12554.8 KKK15917.1 - 4.5e-19 67.9 2.8 8.2e-16 57.5 0.3 2.1 2 0 0 2 2 2 2 Mitotic-spindle organizing gamma-tubulin ring associated SRP54_N PF02881.19 KKK15917.1 - 0.057 13.6 0.2 0.13 12.5 0.0 1.6 2 0 0 2 2 2 0 SRP54-type protein, helical bundle domain PITH PF06201.13 KKK15918.1 - 1.5e-43 148.6 0.0 1.8e-43 148.4 0.0 1.1 1 0 0 1 1 1 1 PITH domain NicO PF03824.16 KKK15918.1 - 2.1 7.6 3.7 2.8 7.2 3.7 1.1 1 0 0 1 1 1 0 High-affinity nickel-transport protein HA2 PF04408.23 KKK15919.1 - 9.2e-17 61.3 0.0 1.9e-16 60.3 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KKK15919.1 - 9e-13 48.4 0.0 2.3e-12 47.1 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KKK15919.1 - 4.6e-12 46.3 0.0 1e-11 45.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KKK15919.1 - 1.2e-05 25.2 0.0 2.3e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KKK15919.1 - 0.00011 22.5 0.0 0.0003 21.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KKK15919.1 - 0.00017 21.4 0.0 0.00035 20.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KKK15919.1 - 0.00023 21.5 0.0 0.00058 20.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain cobW PF02492.19 KKK15919.1 - 0.02 14.5 0.1 0.083 12.5 0.0 1.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain T2SSE PF00437.20 KKK15919.1 - 0.024 13.7 0.2 0.079 12.0 0.0 1.9 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_14 PF13173.6 KKK15919.1 - 0.038 14.0 0.1 3.9 7.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain Herpes_ori_bp PF02399.15 KKK15919.1 - 0.039 12.0 0.0 0.057 11.5 0.0 1.2 1 0 0 1 1 1 0 Origin of replication binding protein DUF2075 PF09848.9 KKK15919.1 - 0.079 12.2 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) FBPase_2 PF06874.11 KKK15919.1 - 0.083 11.2 0.0 0.14 10.5 0.0 1.2 1 0 0 1 1 1 0 Firmicute fructose-1,6-bisphosphatase AAA_23 PF13476.6 KKK15919.1 - 0.096 13.2 0.0 0.32 11.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain Snf7 PF03357.21 KKK15920.1 - 1e-35 122.9 2.5 1.5e-35 122.3 2.5 1.2 1 0 0 1 1 1 1 Snf7 MR_MLE_N PF02746.16 KKK15920.1 - 0.041 14.1 0.1 0.31 11.2 0.0 2.2 2 0 0 2 2 2 0 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain AAA PF00004.29 KKK15921.1 - 2.5e-89 296.5 0.0 3.5e-44 150.4 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KKK15921.1 - 5e-22 77.4 0.4 1.5e-09 37.5 0.0 3.1 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 KKK15921.1 - 6.6e-14 52.7 0.5 0.00019 21.8 0.1 4.3 2 2 1 3 3 3 2 AAA ATPase domain RuvB_N PF05496.12 KKK15921.1 - 7.4e-14 51.8 0.0 1.8e-06 27.8 0.0 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KKK15921.1 - 8.2e-14 52.0 0.4 0.0092 16.3 0.0 5.7 3 2 3 6 6 5 2 AAA domain AAA_2 PF07724.14 KKK15921.1 - 6.5e-11 42.6 0.0 0.00011 22.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 KKK15921.1 - 7e-11 42.3 0.2 0.00078 19.5 0.1 3.8 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 KKK15921.1 - 1.8e-10 41.2 0.0 6.2e-05 23.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.13 KKK15921.1 - 6.9e-09 35.4 0.0 0.00011 21.6 0.0 2.4 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_14 PF13173.6 KKK15921.1 - 5.4e-08 32.9 0.0 0.0041 17.1 0.0 2.8 3 0 0 3 3 2 2 AAA domain RNA_helicase PF00910.22 KKK15921.1 - 1.1e-07 32.2 0.0 0.0092 16.4 0.0 2.7 2 1 0 2 2 2 2 RNA helicase Mg_chelatase PF01078.21 KKK15921.1 - 4.4e-07 29.5 0.6 0.021 14.2 0.1 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 KKK15921.1 - 6.8e-07 29.2 0.1 0.031 14.0 0.0 2.6 2 1 0 2 2 2 2 IstB-like ATP binding protein AAA_28 PF13521.6 KKK15921.1 - 6.9e-07 29.6 0.0 0.016 15.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 KKK15921.1 - 8.9e-07 29.5 0.0 0.034 14.7 0.0 3.1 2 1 0 2 2 2 2 AAA domain AAA_3 PF07726.11 KKK15921.1 - 1.1e-06 28.5 0.0 0.0038 17.1 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 KKK15921.1 - 2.4e-06 26.9 0.0 0.064 12.5 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin TsaE PF02367.17 KKK15921.1 - 6.3e-06 26.2 0.0 0.087 12.8 0.0 2.3 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 KKK15921.1 - 6.5e-06 26.2 0.2 0.14 12.1 0.0 3.6 3 1 1 4 4 3 2 NACHT domain Cytidylate_kin2 PF13189.6 KKK15921.1 - 7.8e-06 26.1 0.0 0.002 18.3 0.0 2.3 2 0 0 2 2 2 1 Cytidylate kinase-like family AAA_25 PF13481.6 KKK15921.1 - 8e-06 25.6 0.9 0.83 9.2 0.0 4.0 3 1 1 4 4 4 2 AAA domain Rad17 PF03215.15 KKK15921.1 - 8.3e-06 25.8 0.0 0.049 13.5 0.0 2.7 2 0 0 2 2 2 2 Rad17 P-loop domain AAA_7 PF12775.7 KKK15921.1 - 1.4e-05 24.7 0.0 0.048 13.2 0.0 2.6 2 1 0 2 2 2 2 P-loop containing dynein motor region ATPase PF06745.13 KKK15921.1 - 3.2e-05 23.4 0.1 0.51 9.6 0.0 3.2 2 1 1 3 3 3 2 KaiC ABC_tran PF00005.27 KKK15921.1 - 3.5e-05 24.3 0.0 0.29 11.6 0.0 2.8 3 0 0 3 3 2 2 ABC transporter AAA_17 PF13207.6 KKK15921.1 - 6.2e-05 23.4 0.0 0.12 12.7 0.0 2.9 2 1 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 KKK15921.1 - 0.00013 21.7 0.0 0.34 10.6 0.0 2.9 3 0 0 3 3 3 2 Sigma-54 interaction domain TniB PF05621.11 KKK15921.1 - 0.00022 20.7 0.0 0.23 10.9 0.0 3.2 3 0 0 3 3 3 1 Bacterial TniB protein PhoH PF02562.16 KKK15921.1 - 0.00023 20.7 0.0 0.37 10.2 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein AAA_11 PF13086.6 KKK15921.1 - 0.00028 20.7 1.9 1.2 8.9 0.0 3.2 3 0 0 3 3 3 2 AAA domain AFG1_ATPase PF03969.16 KKK15921.1 - 0.0004 19.4 0.1 0.092 11.6 0.0 2.6 2 1 0 2 2 2 1 AFG1-like ATPase SKI PF01202.22 KKK15921.1 - 0.00058 20.0 0.0 0.6 10.2 0.0 2.7 2 0 0 2 2 2 1 Shikimate kinase AAA_24 PF13479.6 KKK15921.1 - 0.00066 19.5 0.0 0.92 9.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain Sigma54_activ_2 PF14532.6 KKK15921.1 - 0.0009 19.4 0.0 2.4 8.3 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain NB-ARC PF00931.22 KKK15921.1 - 0.00093 18.4 0.0 0.99 8.5 0.0 2.7 3 0 0 3 3 3 1 NB-ARC domain ATPase_2 PF01637.18 KKK15921.1 - 0.0011 18.9 0.0 1.9 8.3 0.0 3.4 2 2 1 3 3 3 1 ATPase domain predominantly from Archaea Parvo_NS1 PF01057.17 KKK15921.1 - 0.0013 17.9 0.0 1.6 7.8 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 Viral_helicase1 PF01443.18 KKK15921.1 - 0.0027 17.5 0.0 1.4 8.6 0.0 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase DUF815 PF05673.13 KKK15921.1 - 0.003 16.8 0.0 0.068 12.3 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_19 PF13245.6 KKK15921.1 - 0.013 15.8 2.6 2.9 8.2 0.3 3.3 2 1 0 2 2 2 0 AAA domain IPT PF01745.16 KKK15921.1 - 0.014 14.8 0.0 1.4 8.3 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase DUF384 PF04064.13 KKK15921.1 - 0.016 15.1 0.5 0.052 13.4 0.2 2.0 2 0 0 2 2 1 0 Domain of unknown function (DUF384) DUF2075 PF09848.9 KKK15921.1 - 0.033 13.4 0.0 3.2 6.9 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) NTPase_1 PF03266.15 KKK15921.1 - 0.038 13.9 0.0 6.8 6.6 0.0 2.9 2 1 1 3 3 3 0 NTPase CPT PF07931.12 KKK15921.1 - 0.04 13.8 0.0 0.97 9.2 0.0 2.4 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein AAA_30 PF13604.6 KKK15921.1 - 0.046 13.5 0.1 18 4.9 0.0 3.1 4 0 0 4 4 3 0 AAA domain ResIII PF04851.15 KKK15921.1 - 0.051 13.6 0.0 14 5.6 0.0 2.7 3 0 0 3 3 2 0 Type III restriction enzyme, res subunit Cytidylate_kin PF02224.18 KKK15921.1 - 0.1 12.3 0.1 7.6 6.2 0.0 2.4 2 0 0 2 2 2 0 Cytidylate kinase Hydin_ADK PF17213.3 KKK15921.1 - 0.12 12.6 4.9 2.5 8.4 0.0 3.0 3 0 0 3 3 3 0 Hydin Adenylate kinase-like domain AAA_23 PF13476.6 KKK15921.1 - 0.25 11.8 0.9 5.3 7.5 0.0 2.8 3 0 0 3 3 2 0 AAA domain Ribosomal_L27 PF01016.19 KKK15946.1 - 2.6e-29 101.1 0.0 4.9e-29 100.2 0.0 1.5 1 0 0 1 1 1 1 Ribosomal L27 protein Rad9_Rad53_bind PF08605.10 KKK15947.1 - 6.3e-32 110.5 0.0 9.8e-32 109.9 0.0 1.3 1 0 0 1 1 1 1 Fungal Rad9-like Rad53-binding Tudor_3 PF18115.1 KKK15947.1 - 5.9e-21 74.1 0.0 1.3e-20 72.9 0.0 1.6 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain BRCT_2 PF16589.5 KKK15947.1 - 2.5e-06 27.8 0.0 6e-06 26.6 0.0 1.7 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 KKK15947.1 - 5.4e-05 23.5 0.0 0.00053 20.3 0.0 2.7 2 1 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain RTT107_BRCT_5 PF16770.5 KKK15947.1 - 0.00013 21.8 0.0 0.00029 20.7 0.0 1.6 1 0 0 1 1 1 1 Regulator of Ty1 transposition protein 107 BRCT domain BRCT_3 PF18428.1 KKK15947.1 - 0.08 13.0 0.0 11 6.1 0.0 2.5 2 0 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain tRNA_int_endo PF01974.17 KKK15948.1 - 1.2e-19 70.1 1.0 4.8e-19 68.2 1.0 1.9 1 1 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.14 KKK15948.1 - 1.8e-06 27.5 0.0 0.017 14.8 0.0 2.3 2 0 0 2 2 2 2 tRNA intron endonuclease, N-terminal domain Cas_GSU0054 PF09609.10 KKK15948.1 - 0.071 11.8 0.0 0.14 10.8 0.0 1.4 2 0 0 2 2 2 0 CRISPR-associated protein, GSU0054 family (Cas_GSU0054) Nop10p PF04135.12 KKK15949.1 - 2.7e-24 84.9 0.9 3.3e-24 84.7 0.9 1.1 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family NOB1_Zn_bind PF08772.11 KKK15950.1 - 6.1e-33 112.8 4.3 1.1e-32 112.0 4.3 1.4 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like PIN_6 PF17146.4 KKK15950.1 - 1.7e-30 105.4 0.1 5.2e-30 103.8 0.0 1.9 2 0 0 2 2 2 1 PIN domain of ribonuclease DZR PF12773.7 KKK15950.1 - 0.021 14.8 0.8 0.044 13.8 0.8 1.5 1 0 0 1 1 1 0 Double zinc ribbon zinc_ribbon_15 PF17032.5 KKK15950.1 - 0.024 15.4 0.7 0.048 14.4 0.7 1.5 1 0 0 1 1 1 0 zinc-ribbon family HypA PF01155.19 KKK15950.1 - 0.047 13.7 0.5 0.67 10.0 0.9 2.3 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-NADH-PPase PF09297.11 KKK15950.1 - 0.34 10.6 4.5 0.15 11.7 0.6 2.3 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain Zn-ribbon_8 PF09723.10 KKK15950.1 - 0.4 10.8 3.3 0.4 10.8 1.3 2.1 2 0 0 2 2 2 0 Zinc ribbon domain DUF3995 PF13160.6 KKK15951.1 - 0.33 11.3 8.3 3.6 8.0 1.1 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3995) DUF373 PF04123.13 KKK15951.1 - 0.66 9.4 2.7 0.92 8.9 2.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF373) Peptidase_M18 PF02127.15 KKK15952.1 - 5.5e-135 450.5 0.0 6.3e-135 450.3 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) UQ_con PF00179.26 KKK15953.1 - 1.5e-50 170.5 0.0 1.7e-50 170.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Scramblase PF03803.15 KKK15954.1 - 3.2e-54 183.6 1.1 4.2e-29 101.4 0.1 3.0 2 1 0 2 2 2 2 Scramblase Ribosomal_S18 PF01084.20 KKK15954.1 - 0.22 11.8 0.1 0.49 10.7 0.1 1.5 1 0 0 1 1 1 0 Ribosomal protein S18 SGS PF05002.15 KKK15955.1 - 1.3e-27 95.7 4.7 6.8e-27 93.4 4.7 2.1 1 1 0 1 1 1 1 SGS domain CS PF04969.16 KKK15955.1 - 4.2e-10 40.5 0.1 7.1e-10 39.8 0.1 1.4 1 0 0 1 1 1 1 CS domain TPR_1 PF00515.28 KKK15955.1 - 0.0017 18.1 0.0 1.9 8.4 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 KKK15955.1 - 0.002 18.1 0.3 1.8 8.8 0.2 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 KKK15955.1 - 0.0071 17.0 5.5 1.4 9.6 0.5 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat Dicty_REP PF05086.12 KKK15955.1 - 0.26 9.2 4.8 0.33 8.9 4.8 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein SOG2 PF10428.9 KKK15955.1 - 0.3 10.2 8.2 0.39 9.9 8.2 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein SQHop_cyclase_C PF13243.6 KKK15956.1 - 1e-49 169.4 0.1 1.3e-46 159.2 0.9 2.2 2 0 0 2 2 2 2 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 KKK15956.1 - 7.5e-46 156.5 1.4 6.9e-39 133.7 0.1 3.5 3 1 1 4 4 4 2 Squalene-hopene cyclase N-terminal domain Prenyltrans PF00432.21 KKK15956.1 - 7.9e-34 115.1 8.5 5e-11 42.1 0.3 5.1 5 0 0 5 5 5 3 Prenyltransferase and squalene oxidase repeat TED_complement PF07678.14 KKK15956.1 - 1.1e-05 24.7 0.2 0.018 14.1 0.5 3.6 1 1 2 3 3 3 2 A-macroglobulin TED domain Pec_lyase PF09492.10 KKK15956.1 - 0.001 18.5 3.5 0.56 9.5 0.0 3.9 3 1 1 5 5 5 2 Pectic acid lyase TSGP1 PF07771.11 KKK15956.1 - 0.019 15.1 0.0 0.038 14.1 0.0 1.4 1 0 0 1 1 1 0 Tick salivary peptide group 1 TP6A_N PF04406.14 KKK15957.1 - 6.9e-19 67.6 0.0 1.4e-18 66.6 0.0 1.5 1 0 0 1 1 1 1 Type IIB DNA topoisomerase Pkinase PF00069.25 KKK15958.1 - 1e-75 254.6 0.0 1.2e-75 254.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK15958.1 - 5.2e-37 127.5 0.0 7.5e-37 127.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KKK15958.1 - 0.0002 20.4 0.0 0.0014 17.6 0.0 2.0 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KKK15958.1 - 0.0019 17.6 0.2 0.0043 16.4 0.2 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KKK15958.1 - 0.0086 15.4 1.4 0.011 15.0 0.1 1.9 2 1 1 3 3 3 1 Kinase-like CAP_N PF01213.19 KKK15958.1 - 0.099 12.1 2.5 0.19 11.2 2.5 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal APH PF01636.23 KKK15958.1 - 0.24 11.3 0.0 0.24 11.3 0.0 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family Mito_fiss_reg PF05308.11 KKK15958.1 - 0.29 11.2 7.8 0.096 12.8 2.4 2.1 2 0 0 2 2 2 0 Mitochondrial fission regulator PRIMA1 PF16101.5 KKK15958.1 - 3.3 7.8 8.6 6.7 6.8 8.6 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 SIR2 PF02146.17 KKK15959.1 - 1.5e-31 109.7 0.0 2e-31 109.3 0.0 1.2 1 0 0 1 1 1 1 Sir2 family DUF3716 PF12511.8 KKK15960.1 - 1.3e-14 53.9 6.3 2e-14 53.3 6.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) MPP6 PF10175.9 KKK15960.1 - 0.0012 19.3 10.4 0.0097 16.4 1.3 2.3 2 0 0 2 2 2 1 M-phase phosphoprotein 6 HCMV_UL139 PF12507.8 KKK15960.1 - 0.0017 18.7 0.3 0.7 10.3 0.0 2.7 1 1 1 2 2 2 1 Human Cytomegalovirus UL139 protein PPP4R2 PF09184.11 KKK15960.1 - 0.0034 17.0 3.8 0.0034 17.0 3.8 2.1 2 0 0 2 2 2 1 PPP4R2 Prothymosin PF03247.14 KKK15960.1 - 0.012 16.1 38.9 0.019 15.4 20.6 2.2 2 0 0 2 2 2 0 Prothymosin/parathymosin family Zip PF02535.22 KKK15960.1 - 0.012 14.8 0.1 0.012 14.8 0.1 1.7 2 0 0 2 2 2 0 ZIP Zinc transporter Mak16 PF04874.14 KKK15960.1 - 0.016 15.8 24.1 0.44 11.2 12.3 2.2 2 0 0 2 2 2 0 Mak16 protein C-terminal region RR_TM4-6 PF06459.12 KKK15960.1 - 0.019 14.8 1.0 0.019 14.8 1.0 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 CENP-B_dimeris PF09026.10 KKK15960.1 - 0.023 15.1 6.1 0.023 15.1 6.1 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain RNA_pol_Rpc4 PF05132.14 KKK15960.1 - 0.025 15.0 1.7 0.29 11.5 0.1 2.2 2 0 0 2 2 2 0 RNA polymerase III RPC4 Nop25 PF09805.9 KKK15960.1 - 0.037 14.5 18.5 0.16 12.5 3.5 2.1 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) PTPRCAP PF15713.5 KKK15960.1 - 0.082 13.2 20.3 0.16 12.3 9.7 2.2 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated BUD22 PF09073.10 KKK15960.1 - 0.14 11.5 17.3 0.22 10.8 17.3 1.2 1 0 0 1 1 1 0 BUD22 FAM176 PF14851.6 KKK15960.1 - 0.15 11.7 18.1 0.047 13.3 7.0 2.2 2 0 0 2 2 2 0 FAM176 family Mntp PF02659.15 KKK15960.1 - 0.15 11.8 0.8 0.23 11.2 0.0 1.7 2 0 0 2 2 1 0 Putative manganese efflux pump Perilipin PF03036.16 KKK15960.1 - 0.34 9.9 7.3 0.5 9.3 7.3 1.2 1 0 0 1 1 1 0 Perilipin family RPN2_C PF18004.1 KKK15960.1 - 0.36 10.7 19.0 0.25 11.2 7.5 2.1 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain TFB6 PF17110.5 KKK15960.1 - 0.47 10.2 8.3 1 9.1 3.0 2.2 2 0 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH CDC27 PF09507.10 KKK15960.1 - 0.59 9.5 13.1 0.6 9.4 4.9 2.0 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 PBP1_TM PF14812.6 KKK15960.1 - 0.6 10.5 11.1 0.31 11.4 2.9 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal U1snRNP70_N PF12220.8 KKK15960.1 - 0.73 10.5 12.0 2 9.1 0.8 2.3 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Presenilin PF01080.17 KKK15960.1 - 0.96 8.1 6.1 1.4 7.6 6.1 1.2 1 0 0 1 1 1 0 Presenilin CobT PF06213.12 KKK15960.1 - 1 8.7 20.2 3.6 6.9 0.9 2.2 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT eIF-3c_N PF05470.12 KKK15960.1 - 1.2 7.4 8.5 1.6 6.9 8.5 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus DUF4366 PF14283.6 KKK15960.1 - 1.3 9.1 7.4 3.3 7.7 2.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) DUF5523 PF17661.1 KKK15960.1 - 1.4 8.5 20.5 0.12 12.1 7.4 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5523) GEN1_C PF18380.1 KKK15960.1 - 1.5 9.8 16.7 0.38 11.7 6.4 2.2 2 0 0 2 2 2 0 Holliday junction resolvase Gen1 C-terminal domain AIM3 PF17096.5 KKK15960.1 - 1.6 9.8 7.5 4.5 8.3 2.9 2.3 2 0 0 2 2 2 0 Altered inheritance of mitochondria protein 3 MAM33 PF02330.16 KKK15960.1 - 1.6 8.6 17.8 0.035 14.1 4.1 2.1 2 0 0 2 2 2 0 Mitochondrial glycoprotein PAXIP1_C PF15364.6 KKK15960.1 - 1.7 9.0 17.8 0.32 11.3 5.1 2.3 2 0 0 2 2 2 0 PAXIP1-associated-protein-1 C term PTIP binding protein DUF719 PF05334.13 KKK15960.1 - 1.9 8.7 9.7 0.78 9.9 1.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF719) DUF1738 PF08401.11 KKK15960.1 - 2.2 8.4 8.7 9 6.4 2.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1738) G0-G1_switch_2 PF15103.6 KKK15960.1 - 2.3 8.7 7.6 4.7 7.7 3.0 2.2 2 0 0 2 2 2 0 G0/G1 switch protein 2 DUF4820 PF16091.5 KKK15960.1 - 2.8 7.2 9.7 0.15 11.4 1.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) RXT2_N PF08595.11 KKK15960.1 - 2.9 7.9 15.3 0.41 10.7 5.1 2.2 2 0 0 2 2 2 0 RXT2-like, N-terminal RMI1_N PF08585.12 KKK15960.1 - 3.3 7.4 6.8 0.42 10.3 1.4 2.1 3 0 0 3 3 2 0 RecQ mediated genome instability protein RNA_polI_A34 PF08208.11 KKK15960.1 - 5.8 6.9 19.6 1.3 9.0 1.7 2.1 2 0 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 Pox_Ag35 PF03286.14 KKK15960.1 - 6.1 6.6 18.5 0.34 10.7 6.5 2.2 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Nop14 PF04147.12 KKK15960.1 - 6.5 4.8 23.2 2.5 6.2 13.3 2.0 2 0 0 2 2 2 0 Nop14-like family DNA_pol_phi PF04931.13 KKK15960.1 - 6.7 4.7 26.9 0.065 11.3 10.8 2.0 2 0 0 2 2 2 0 DNA polymerase phi Nop53 PF07767.11 KKK15960.1 - 7.9 5.8 25.3 6.4 6.1 3.4 2.1 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) TLP-20 PF06088.11 KKK15960.1 - 8.9 6.2 9.6 0.94 9.3 2.1 2.1 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) DUF3391 PF11871.8 KKK15960.1 - 9.1 6.8 13.3 1.2 9.7 5.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) Paf1 PF03985.13 KKK15960.1 - 9.6 5.1 29.6 1.2 8.0 14.9 2.1 2 0 0 2 2 2 0 Paf1 PQ-loop PF04193.14 KKK15961.1 - 2e-39 133.2 17.8 6.9e-21 73.8 1.3 3.1 3 0 0 3 3 3 2 PQ loop repeat DUF2157 PF09925.9 KKK15961.1 - 0.02 14.7 1.1 2.8 7.7 1.7 2.6 2 1 0 2 2 2 0 Predicted membrane protein (DUF2157) DUF1294 PF06961.13 KKK15961.1 - 0.11 12.8 0.8 0.65 10.3 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1294) Dicty_CAR PF05462.11 KKK15962.1 - 1.4e-14 54.0 17.3 9.2e-14 51.3 11.2 2.1 2 0 0 2 2 2 2 Slime mold cyclic AMP receptor 7tm_2 PF00002.24 KKK15962.1 - 8.3e-12 44.9 6.8 1.3e-11 44.3 6.8 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) 7tm_1 PF00001.21 KKK15962.1 - 5.5e-09 35.7 0.8 7.7e-09 35.3 0.8 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Git3 PF11710.8 KKK15962.1 - 1.5e-06 28.1 13.6 1.5e-06 28.1 13.6 1.5 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 7TM_GPCR_Srsx PF10320.9 KKK15962.1 - 0.0011 18.4 3.5 0.0011 18.4 3.5 1.8 3 0 0 3 3 3 1 Serpentine type 7TM GPCR chemoreceptor Srsx Frizzled PF01534.17 KKK15962.1 - 0.018 14.1 13.2 0.0077 15.3 7.9 2.2 1 1 1 2 2 2 0 Frizzled/Smoothened family membrane region TMEMspv1-c74-12 PF11044.8 KKK15962.1 - 0.083 12.9 0.1 0.16 12.0 0.1 1.4 1 0 0 1 1 1 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein SRP54 PF00448.22 KKK15963.1 - 1.9e-74 249.5 3.4 3.4e-74 248.7 3.4 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 KKK15963.1 - 1.8e-29 102.2 0.3 1.8e-29 102.2 0.3 4.0 3 1 0 3 3 2 1 Signal peptide binding domain SRP54_N PF02881.19 KKK15963.1 - 1.9e-20 72.8 0.5 5e-20 71.5 0.5 1.8 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain cobW PF02492.19 KKK15963.1 - 6.2e-07 29.2 0.3 1.5e-06 27.9 0.3 1.7 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.6 KKK15963.1 - 5.7e-06 26.8 0.1 2e-05 25.0 0.1 1.9 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KKK15963.1 - 1.9e-05 24.8 0.3 5.7e-05 23.3 0.1 2.0 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KKK15963.1 - 9.7e-05 22.8 0.0 0.00024 21.5 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain MeaB PF03308.16 KKK15963.1 - 0.00074 18.6 0.1 0.00074 18.6 0.1 2.5 2 2 1 3 3 3 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Zeta_toxin PF06414.12 KKK15963.1 - 0.00081 18.7 0.1 0.0017 17.7 0.1 1.5 1 0 0 1 1 1 1 Zeta toxin APS_kinase PF01583.20 KKK15963.1 - 0.0015 18.4 0.0 0.0032 17.4 0.0 1.6 1 0 0 1 1 1 1 Adenylylsulphate kinase SRPRB PF09439.10 KKK15963.1 - 0.002 17.6 1.1 1.4 8.3 0.9 3.1 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit CbiA PF01656.23 KKK15963.1 - 0.002 18.2 0.0 0.004 17.2 0.0 1.8 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_30 PF13604.6 KKK15963.1 - 0.0022 17.8 0.6 0.0062 16.3 0.6 1.8 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KKK15963.1 - 0.0047 17.5 0.0 0.011 16.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 KKK15963.1 - 0.0053 16.8 0.2 0.056 13.5 0.1 2.5 2 1 0 2 2 2 1 50S ribosome-binding GTPase ResIII PF04851.15 KKK15963.1 - 0.0056 16.7 0.3 0.013 15.5 0.3 1.7 2 0 0 2 2 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KKK15963.1 - 0.0068 16.7 0.0 0.029 14.7 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 KKK15963.1 - 0.0092 16.2 0.0 0.018 15.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain 6PF2K PF01591.18 KKK15963.1 - 0.012 15.0 0.0 0.02 14.2 0.0 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase ATP_bind_1 PF03029.17 KKK15963.1 - 0.014 15.2 0.5 0.036 13.8 0.1 1.9 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Thymidylate_kin PF02223.17 KKK15963.1 - 0.018 14.7 0.2 0.062 13.0 0.1 2.0 2 0 0 2 2 1 0 Thymidylate kinase MobB PF03205.14 KKK15963.1 - 0.02 14.8 0.2 0.053 13.4 0.0 1.8 2 0 0 2 2 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_31 PF13614.6 KKK15963.1 - 0.086 12.7 0.1 0.2 11.6 0.1 1.7 1 0 0 1 1 1 0 AAA domain Arf PF00025.21 KKK15963.1 - 0.14 11.6 0.0 0.34 10.3 0.0 1.6 1 0 0 1 1 1 0 ADP-ribosylation factor family Rrp15p PF07890.12 KKK15964.1 - 2.6e-37 128.1 8.8 2.6e-37 128.1 8.8 2.2 2 0 0 2 2 2 1 Rrp15p Fer2 PF00111.27 KKK15965.1 - 7.1e-13 48.3 0.8 1e-12 47.8 0.8 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Mito_carr PF00153.27 KKK15966.1 - 1.3e-08 34.6 7.1 0.012 15.5 0.1 4.8 4 1 0 4 4 4 3 Mitochondrial carrier protein PBP1_TM PF14812.6 KKK15966.1 - 0.045 14.1 5.6 0.075 13.4 5.6 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CDC45 PF02724.14 KKK15966.1 - 0.061 11.6 0.1 0.076 11.3 0.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Apt1 PF10351.9 KKK15966.1 - 0.22 10.4 1.7 0.28 10.0 1.7 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Sporozoite_P67 PF05642.11 KKK15966.1 - 0.39 8.8 3.5 0.71 7.9 3.5 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen bZIP_1 PF00170.21 KKK15967.1 - 3e-07 30.5 10.0 1.9e-05 24.6 10.6 2.7 1 1 1 2 2 2 1 bZIP transcription factor Hap4_Hap_bind PF10297.9 KKK15967.1 - 6.6e-07 29.2 6.7 6.6e-07 29.2 6.7 2.1 2 0 0 2 2 1 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 TRAF_BIRC3_bd PF16673.5 KKK15967.1 - 0.038 13.8 0.7 0.038 13.8 0.7 2.1 2 1 0 2 2 2 0 TNF receptor-associated factor BIRC3 binding domain DUF2408 PF10303.9 KKK15967.1 - 0.11 13.1 0.5 0.22 12.1 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) dsrm PF00035.26 KKK15967.1 - 0.11 13.3 0.0 0.24 12.1 0.0 1.5 1 0 0 1 1 1 0 Double-stranded RNA binding motif HIP1_clath_bdg PF16515.5 KKK15967.1 - 0.22 12.1 2.6 0.49 11.0 2.6 1.6 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF3584 PF12128.8 KKK15967.1 - 0.24 8.9 4.3 0.33 8.4 4.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Replic_Relax PF13814.6 KKK15967.1 - 0.85 9.6 3.2 0.52 10.3 1.2 1.6 2 0 0 2 2 2 0 Replication-relaxation FAM184 PF15665.5 KKK15967.1 - 1.3 8.8 7.8 2.1 8.1 7.8 1.3 1 1 0 1 1 1 0 Family with sequence similarity 184, A and B V_ATPase_I PF01496.19 KKK15967.1 - 1.8 6.4 3.4 2.2 6.1 3.4 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Spc29 PF17082.5 KKK15967.1 - 1.8 8.3 4.9 0.27 11.1 1.0 1.6 2 0 0 2 2 2 0 Spindle Pole Component 29 bZIP_2 PF07716.15 KKK15967.1 - 4.2 7.5 21.1 0.3 11.2 11.7 3.0 2 1 0 2 2 2 0 Basic region leucine zipper Glyco_hydro_71 PF03659.14 KKK15968.1 - 9.7e-138 459.0 0.1 1.4e-137 458.5 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 Pkinase PF00069.25 KKK15998.1 - 6.9e-17 61.7 0.0 7.2e-16 58.3 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK15998.1 - 0.00039 19.8 0.0 0.00057 19.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase GCS PF03074.16 KKK15999.1 - 1.1e-174 581.1 0.0 1.4e-174 580.7 0.0 1.1 1 0 0 1 1 1 1 Glutamate-cysteine ligase Cytochrom_B561 PF03188.16 KKK15999.1 - 0.23 11.6 0.0 6.4 6.9 0.0 2.2 2 0 0 2 2 2 0 Eukaryotic cytochrome b561 NDUF_B7 PF05676.13 KKK16000.1 - 4e-30 103.3 6.6 4.8e-30 103.1 6.6 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.10 KKK16000.1 - 0.018 15.1 2.4 0.024 14.6 2.4 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like Ank_4 PF13637.6 KKK16001.1 - 8.6e-14 51.7 0.7 1.1e-05 25.8 0.0 3.2 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KKK16001.1 - 6.5e-11 42.7 0.0 9.3e-06 26.2 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KKK16001.1 - 6.8e-10 39.0 0.3 9.3e-06 25.8 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KKK16001.1 - 1.3e-09 37.5 0.7 0.00037 20.7 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 KKK16001.1 - 1.3e-08 34.8 0.7 9.2e-06 25.9 0.1 3.5 3 0 0 3 3 3 1 Ankyrin repeat KilA-N PF04383.13 KKK16001.1 - 0.00015 21.6 0.0 0.00051 19.9 0.0 1.9 1 0 0 1 1 1 1 KilA-N domain HALZ PF02183.18 KKK16001.1 - 1.3 9.3 4.9 3.3 8.0 0.1 2.4 2 0 0 2 2 2 0 Homeobox associated leucine zipper ThrE PF06738.12 KKK16003.1 - 5.8e-76 255.0 17.4 7.6e-71 238.3 3.5 2.3 2 0 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 KKK16003.1 - 1.2e-07 31.9 15.5 1.2e-07 31.9 15.5 2.9 2 1 0 2 2 2 1 Threonine/Serine exporter, ThrE 2OG-FeII_Oxy_3 PF13640.6 KKK16005.1 - 4.6e-07 30.7 0.0 8.5e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily adh_short_C2 PF13561.6 KKK16006.1 - 1.4e-53 181.9 0.2 4e-29 101.8 0.0 2.0 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KKK16006.1 - 1.2e-42 145.6 0.7 3.1e-28 98.6 0.2 2.1 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 KKK16006.1 - 1.3e-11 44.8 0.1 2e-11 44.1 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KKK16006.1 - 0.0032 16.9 0.2 0.029 13.8 0.1 1.9 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Alk_phosphatase PF00245.20 KKK16006.1 - 0.069 12.1 0.0 0.097 11.6 0.0 1.1 1 0 0 1 1 1 0 Alkaline phosphatase GDP_Man_Dehyd PF16363.5 KKK16006.1 - 0.17 11.3 0.1 0.39 10.1 0.0 1.7 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase PLA2_B PF01735.18 KKK16007.1 - 4.3e-179 596.0 12.9 6.2e-162 539.4 0.6 2.1 1 1 1 2 2 2 2 Lysophospholipase catalytic domain Xpo1 PF08389.12 KKK16018.1 - 2.3e-10 40.7 5.2 1.9e-08 34.5 1.2 4.4 3 2 0 3 3 3 1 Exportin 1-like protein Arabinose_trans PF04602.12 KKK16018.1 - 0.023 13.6 0.0 0.04 12.7 0.0 1.3 1 0 0 1 1 1 0 Mycobacterial cell wall arabinan synthesis protein GRIM-19 PF06212.12 KKK16019.1 - 5e-22 78.3 0.2 1.8e-21 76.5 0.2 1.7 1 1 0 1 1 1 1 GRIM-19 protein tRNA_m1G_MT PF01746.21 KKK16020.1 - 3.5e-25 88.8 0.0 9.4e-25 87.5 0.0 1.7 1 1 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase XAP5 PF04921.14 KKK16020.1 - 0.093 12.5 4.0 0.15 11.9 4.0 1.5 1 0 0 1 1 1 0 XAP5, circadian clock regulator Presenilin PF01080.17 KKK16020.1 - 0.7 8.6 1.3 0.74 8.5 1.3 1.2 1 0 0 1 1 1 0 Presenilin VID27 PF08553.10 KKK16021.1 - 1.1e-195 649.6 0.0 1.9e-195 648.9 0.0 1.3 1 0 0 1 1 1 1 VID27 C-terminal WD40-like domain VID27_N PF17748.1 KKK16021.1 - 6.9e-77 257.2 0.2 6.9e-77 257.2 0.2 2.7 2 1 1 3 3 3 1 VID27 N-terminal region VID27_PH PF17747.1 KKK16021.1 - 2.4e-46 156.5 2.0 7.2e-46 155.0 1.1 2.1 2 0 0 2 2 2 1 VID27 PH-like domain Spore_III_AB PF09548.10 KKK16021.1 - 0.69 10.0 4.3 1.8 8.6 4.3 1.6 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) Nop14 PF04147.12 KKK16021.1 - 1.1 7.4 14.7 1.9 6.6 14.7 1.3 1 0 0 1 1 1 0 Nop14-like family DNA_mis_repair PF01119.19 KKK16029.1 - 4.6e-11 42.4 0.0 1e-10 41.3 0.0 1.6 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 KKK16029.1 - 5.5e-09 36.0 0.0 1.6e-08 34.5 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 KKK16029.1 - 1.8e-08 34.8 0.1 4.4e-08 33.6 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Cep57_CLD PF14073.6 KKK16029.1 - 0.054 13.5 3.0 0.11 12.5 3.0 1.4 1 0 0 1 1 1 0 Centrosome localisation domain of Cep57 Mito_carr PF00153.27 KKK16029.1 - 0.075 13.0 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 Mitochondrial carrier protein DHHC PF01529.20 KKK16030.1 - 1.2e-30 106.4 4.1 1.2e-30 106.4 4.1 1.9 2 0 0 2 2 2 1 DHHC palmitoyltransferase Methyltransf_25 PF13649.6 KKK16031.1 - 1.5e-16 60.9 0.0 4.2e-16 59.4 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KKK16031.1 - 2.9e-15 56.7 0.0 5.4e-15 55.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KKK16031.1 - 3.7e-13 49.7 0.0 5e-13 49.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KKK16031.1 - 5.9e-13 49.4 0.0 9.4e-13 48.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KKK16031.1 - 1.8e-10 40.8 0.0 2.6e-10 40.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KKK16031.1 - 6.5e-08 32.3 0.0 9.6e-08 31.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain NodS PF05401.11 KKK16031.1 - 1.2e-05 25.1 0.0 2.1e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Nodulation protein S (NodS) RrnaAD PF00398.20 KKK16031.1 - 1.8e-05 24.0 0.0 0.00031 19.9 0.0 2.1 1 1 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_9 PF08003.11 KKK16031.1 - 2.4e-05 23.4 0.0 3.8e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) PCMT PF01135.19 KKK16031.1 - 7e-05 22.7 0.0 0.00017 21.4 0.0 1.8 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.18 KKK16031.1 - 7.1e-05 22.2 0.0 0.0001 21.7 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family DREV PF05219.12 KKK16031.1 - 0.00031 19.9 0.0 0.00043 19.5 0.0 1.3 1 0 0 1 1 1 1 DREV methyltransferase PrmA PF06325.13 KKK16031.1 - 0.0013 18.2 0.0 0.0019 17.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.20 KKK16031.1 - 0.0049 16.2 0.0 0.0064 15.8 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase TPMT PF05724.11 KKK16031.1 - 0.01 15.5 0.0 0.16 11.6 0.0 2.2 2 0 0 2 2 2 0 Thiopurine S-methyltransferase (TPMT) Methyltransf_32 PF13679.6 KKK16031.1 - 0.058 13.4 0.0 0.099 12.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_5 PF01795.19 KKK16031.1 - 0.21 11.0 0.0 0.3 10.6 0.0 1.2 1 0 0 1 1 1 0 MraW methylase family tRNA_U5-meth_tr PF05958.11 KKK16031.1 - 0.26 10.2 0.0 0.36 9.7 0.0 1.2 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase DUF202 PF02656.15 KKK16032.1 - 3e-16 59.6 0.4 6e-16 58.7 0.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF202) DUF3112 PF11309.8 KKK16033.1 - 4.6e-14 52.4 5.3 1.4e-09 37.8 1.2 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF3112) DUF4407 PF14362.6 KKK16033.1 - 0.061 12.7 1.4 0.11 11.9 1.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF996 PF06195.13 KKK16033.1 - 3.3 8.0 14.8 2 8.7 6.5 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF996) EthD PF07110.11 KKK16034.1 - 0.0073 17.4 0.1 0.062 14.5 0.1 1.9 1 1 0 1 1 1 1 EthD domain PBP PF01161.20 KKK16035.1 - 1.4e-14 54.5 0.1 2e-14 54.0 0.1 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein 2-Hacid_dh_C PF02826.19 KKK16036.1 - 1.5e-32 112.4 0.2 5.1e-26 91.1 0.0 2.2 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain MBOAT_2 PF13813.6 KKK16037.1 - 1.4e-18 66.9 5.1 3.1e-18 65.8 5.1 1.6 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Imp-YgjV PF10688.9 KKK16037.1 - 0.31 10.9 7.1 0.065 13.1 2.8 2.1 2 0 0 2 2 2 0 Bacterial inner membrane protein WD40 PF00400.32 KKK16039.1 - 2e-05 25.3 3.2 0.0012 19.6 0.0 3.9 4 0 0 4 4 4 2 WD domain, G-beta repeat DUF3613 PF12266.8 KKK16040.1 - 0.12 12.2 0.1 0.3 10.9 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3613) FSH1 PF03959.13 KKK16041.1 - 1.6e-27 96.5 0.0 2.1e-27 96.2 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 KKK16041.1 - 0.0027 18.3 1.3 0.0048 17.5 1.3 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 KKK16041.1 - 0.0065 16.3 0.1 0.093 12.5 0.0 2.2 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase ketoacyl-synt PF00109.26 KKK16042.1 - 4.1e-54 183.8 0.1 9.6e-53 179.3 0.1 2.8 2 1 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 KKK16042.1 - 8.2e-37 125.8 0.6 1.8e-36 124.7 0.6 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain HTH_51 PF18558.1 KKK16042.1 - 3.1e-27 94.3 0.0 1.2e-26 92.4 0.0 2.1 1 0 0 1 1 1 1 Helix-turn-helix domain Acyl_transf_1 PF00698.21 KKK16042.1 - 2.9e-24 86.2 0.1 3.1e-22 79.5 0.0 2.6 2 0 0 2 2 2 1 Acyl transferase domain PS-DH PF14765.6 KKK16042.1 - 1.5e-22 80.3 0.0 2.4e-22 79.5 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Methyltransf_23 PF13489.6 KKK16042.1 - 3.2e-16 59.6 0.0 5.4e-15 55.6 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain SAT PF16073.5 KKK16042.1 - 8.1e-15 55.2 6.5 9.2e-13 48.5 0.0 4.0 2 1 1 3 3 3 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Methyltransf_12 PF08242.12 KKK16042.1 - 1.1e-14 54.9 0.0 2.6e-14 53.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.25 KKK16042.1 - 1.3e-12 47.9 1.0 1.3e-12 47.9 1.0 2.2 2 0 0 2 2 1 1 Phosphopantetheine attachment site Methyltransf_25 PF13649.6 KKK16042.1 - 5.4e-12 46.3 0.0 1.7e-11 44.6 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KKK16042.1 - 1.6e-09 38.3 0.1 8.9e-09 35.9 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 KKK16042.1 - 2.3e-08 34.5 0.0 1.5e-07 31.8 0.0 2.4 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension Methyltransf_31 PF13847.6 KKK16042.1 - 1.3e-05 25.1 0.0 3e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.23 KKK16042.1 - 1.6e-05 24.4 0.4 3.4e-05 23.4 0.1 1.6 2 0 0 2 2 2 1 Thiolase, N-terminal domain Ubie_methyltran PF01209.18 KKK16042.1 - 0.0073 15.7 0.0 0.021 14.1 0.0 1.7 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_28 PF02636.17 KKK16042.1 - 0.01 15.5 0.0 0.02 14.5 0.0 1.5 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase ACP_syn_III PF08545.10 KKK16042.1 - 0.18 11.7 3.8 0.12 12.2 0.4 2.4 2 1 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ER_lumen_recept PF00810.18 KKK16059.1 - 1.2e-56 191.6 8.7 2e-56 190.9 8.7 1.3 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.14 KKK16059.1 - 0.00018 21.2 9.4 0.27 11.0 0.1 4.0 3 1 1 4 4 4 3 PQ loop repeat Tlr3_TMD PF17968.1 KKK16059.1 - 4 7.7 8.6 2 8.7 0.3 3.0 3 0 0 3 3 3 0 Toll-like receptor 3 trans-membrane domain XRCC4 PF06632.12 KKK16062.1 - 9.6e-09 34.5 11.5 5.4e-08 32.1 11.5 2.2 1 1 0 1 1 1 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 LAT PF15234.6 KKK16062.1 - 0.081 12.7 7.1 0.15 11.7 7.1 1.4 1 0 0 1 1 1 0 Linker for activation of T-cells NOA36 PF06524.12 KKK16062.1 - 7.3 5.8 9.1 13 5.0 9.1 1.3 1 0 0 1 1 1 0 NOA36 protein DTHCT PF08070.11 KKK16062.1 - 9.1 7.1 13.3 31 5.4 11.1 2.6 1 1 0 1 1 1 0 DTHCT (NUC029) region Ribonuclease_3 PF00636.26 KKK16063.1 - 2.2e-13 50.8 0.0 8.8e-13 48.8 0.0 2.1 2 1 0 2 2 2 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 KKK16063.1 - 2.1e-11 44.1 0.0 3.5e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease-III-like dsrm PF00035.26 KKK16063.1 - 0.00018 22.1 0.0 0.00043 20.9 0.0 1.6 1 0 0 1 1 1 1 Double-stranded RNA binding motif DUF4385 PF14328.6 KKK16064.1 - 0.069 13.2 0.2 9.5 6.3 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4385) Cys_Met_Meta_PP PF01053.20 KKK16065.1 - 5.4e-150 499.2 0.0 6.1e-150 499.0 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 KKK16065.1 - 6.7e-11 42.1 1.4 1.4e-10 41.1 1.4 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 KKK16065.1 - 1.2e-08 34.5 0.2 2.1e-08 33.7 0.2 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KKK16065.1 - 7.2e-08 31.8 0.6 2.4e-07 30.1 0.6 1.7 1 1 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KKK16065.1 - 2.4e-05 23.8 0.0 4.1e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Met_gamma_lyase PF06838.11 KKK16065.1 - 0.0002 20.0 0.0 0.00026 19.7 0.0 1.1 1 0 0 1 1 1 1 Methionine gamma-lyase Asparaginase_C PF17763.1 KKK16065.1 - 0.0015 18.7 0.4 0.0062 16.7 0.1 2.1 2 0 0 2 2 2 1 Glutaminase/Asparaginase C-terminal domain SepSecS PF05889.13 KKK16065.1 - 0.1 11.2 0.0 0.15 10.7 0.0 1.2 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS GDC-P PF02347.16 KKK16065.1 - 0.18 10.6 0.0 0.25 10.1 0.0 1.1 1 0 0 1 1 1 0 Glycine cleavage system P-protein CTD_bind PF04818.13 KKK16066.1 - 2.1e-09 38.0 0.0 4.6e-09 37.0 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase II-binding domain. RRM_1 PF00076.22 KKK16066.1 - 2.6e-05 24.0 0.0 4.6e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AA_permease PF00324.21 KKK16067.1 - 2.6e-135 451.7 51.4 3.2e-135 451.4 51.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KKK16067.1 - 2.8e-34 118.7 57.4 3.4e-34 118.4 57.4 1.1 1 0 0 1 1 1 1 Amino acid permease MARVEL PF01284.23 KKK16068.1 - 8.5e-22 77.7 15.0 9.9e-22 77.5 15.0 1.1 1 0 0 1 1 1 1 Membrane-associating domain Peptidase_M16 PF00675.20 KKK16069.1 - 1.5e-21 76.9 0.0 3.1e-21 75.9 0.0 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 KKK16069.1 - 2.1e-15 57.2 0.0 3.4e-15 56.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase M16 inactive domain DUF530 PF04409.12 KKK16069.1 - 0.066 11.6 0.7 0.12 10.7 0.2 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF530) M16C_assoc PF08367.11 KKK16069.1 - 0.076 12.1 0.0 0.14 11.2 0.0 1.4 1 0 0 1 1 1 0 Peptidase M16C associated RNA_pol_Rpc82 PF05645.13 KKK16070.1 - 9.8e-26 91.0 0.0 2.5e-23 83.2 0.0 2.3 2 0 0 2 2 2 2 RNA polymerase III subunit RPC82 HTH_9 PF08221.11 KKK16070.1 - 1.5e-15 57.0 1.6 6.9e-09 35.7 0.0 3.6 4 0 0 4 4 4 3 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.17 KKK16070.1 - 3.7e-06 26.7 0.3 0.0023 17.8 0.1 2.5 2 0 0 2 2 2 2 TFIIE alpha subunit Sas6_CC PF18594.1 KKK16070.1 - 0.021 14.6 0.4 0.046 13.5 0.4 1.6 1 0 0 1 1 1 0 Sas6/XLF/XRCC4 coiled-coil domain Citrate_synt PF00285.21 KKK16071.1 - 9.8e-101 337.4 0.0 1.3e-100 337.0 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain S8_pro-domain PF16470.5 KKK16071.1 - 0.13 13.1 0.2 2 9.2 0.1 2.4 2 0 0 2 2 2 0 Peptidase S8 pro-domain Mito_carr PF00153.27 KKK16072.1 - 4.7e-28 96.9 4.7 6.8e-13 48.4 0.0 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein DUF2012 PF09430.10 KKK16073.1 - 2.9e-20 72.6 0.0 6.5e-20 71.5 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF2012) AMP-binding PF00501.28 KKK16074.1 - 3.9e-83 279.4 0.0 5.4e-83 278.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme WW PF00397.26 KKK16075.1 - 9.5e-13 48.0 1.2 1.9e-12 47.0 1.2 1.6 1 0 0 1 1 1 1 WW domain WD40 PF00400.32 KKK16076.1 - 2.3e-05 25.0 14.0 0.025 15.4 0.1 6.2 7 0 0 7 7 7 2 WD domain, G-beta repeat Nup160 PF11715.8 KKK16076.1 - 0.0024 16.6 1.2 0.0062 15.2 1.2 1.7 1 1 0 1 1 1 1 Nucleoporin Nup120/160 Raptor_N PF14538.6 KKK16076.1 - 0.12 12.3 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 Raptor N-terminal CASPase like domain Mito_carr PF00153.27 KKK16077.1 - 3.5e-49 164.7 1.3 1.3e-17 63.5 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein AphA_like PF14557.6 KKK16077.1 - 0.021 14.5 0.0 0.048 13.4 0.0 1.6 2 0 0 2 2 2 0 Putative AphA-like transcriptional regulator PrcB_C PF14343.6 KKK16077.1 - 0.048 13.8 0.0 1.7 8.9 0.0 2.5 2 0 0 2 2 2 0 PrcB C-terminal UcrQ PF02939.16 KKK16077.1 - 0.054 13.4 0.1 0.28 11.1 0.1 2.2 2 0 0 2 2 2 0 UcrQ family TadE PF07811.12 KKK16077.1 - 0.14 12.4 0.7 2.1 8.7 0.1 2.5 2 0 0 2 2 2 0 TadE-like protein Ras PF00071.22 KKK16078.1 - 3.1e-23 82.1 0.3 3.7e-23 81.9 0.3 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KKK16078.1 - 0.0023 18.1 0.2 0.0061 16.8 0.1 1.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Peptidase_M1 PF01433.20 KKK16079.1 - 9.2e-85 283.6 5.7 1.4e-84 283.0 4.4 1.9 2 0 0 2 2 2 1 Peptidase family M1 domain ERAP1_C PF11838.8 KKK16079.1 - 3.2e-84 283.2 6.5 7.3e-84 282.0 6.5 1.6 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 KKK16079.1 - 2.6e-44 151.6 0.6 4.5e-43 147.6 0.1 2.5 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain Ssl1 PF04056.14 KKK16080.1 - 9.1e-77 257.2 0.0 1.3e-76 256.7 0.0 1.2 1 0 0 1 1 1 1 Ssl1-like DUF5572 PF17733.1 KKK16080.1 - 5e-24 83.9 0.8 1.1e-23 82.7 0.8 1.7 1 0 0 1 1 1 1 Family of unknown function (DUF5572) VWA_2 PF13519.6 KKK16080.1 - 5.2e-16 59.2 0.0 1e-15 58.3 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 KKK16080.1 - 9.7e-07 29.2 0.0 1.7e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain PsiE PF06146.12 KKK16080.1 - 0.022 15.1 0.0 0.054 13.9 0.0 1.6 1 0 0 1 1 1 0 Phosphate-starvation-inducible E Tfb4 PF03850.14 KKK16080.1 - 0.059 12.8 1.7 0.092 12.2 1.7 1.2 1 0 0 1 1 1 0 Transcription factor Tfb4 PUF PF00806.19 KKK16081.1 - 5e-36 120.4 3.6 2.7e-06 26.8 0.0 9.2 9 0 0 9 9 9 8 Pumilio-family RNA binding repeat CPL PF08144.11 KKK16081.1 - 0.095 13.0 0.1 5.3 7.4 0.0 2.6 2 0 0 2 2 2 0 CPL (NUC119) domain Peptidase_S9 PF00326.21 KKK16082.1 - 7.5e-06 25.6 0.0 1.5e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.20 KKK16082.1 - 4.1e-05 23.4 0.8 0.00017 21.3 0.8 1.9 1 1 0 1 1 1 1 Putative esterase Abhydrolase_2 PF02230.16 KKK16082.1 - 0.0004 20.3 0.1 0.04 13.7 0.0 2.7 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase Chlorophyllase PF07224.11 KKK16082.1 - 0.0049 15.9 0.1 0.0083 15.2 0.1 1.2 1 0 0 1 1 1 1 Chlorophyllase Esterase_phd PF10503.9 KKK16082.1 - 0.0066 16.0 0.1 0.012 15.2 0.1 1.4 1 0 0 1 1 1 1 Esterase PHB depolymerase Abhydrolase_6 PF12697.7 KKK16082.1 - 0.021 15.4 0.9 0.066 13.8 0.9 1.9 1 0 0 1 1 1 0 Alpha/beta hydrolase family TPT PF03151.16 KKK16083.1 - 1.6e-61 208.3 14.0 1.9e-61 207.9 14.0 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KKK16083.1 - 2.9e-09 37.2 29.9 2.3e-05 24.6 10.4 2.8 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 KKK16083.1 - 0.00049 19.4 17.0 0.0026 17.0 17.0 1.9 1 1 0 1 1 1 1 UAA transporter family PSII PF00421.19 KKK16083.1 - 0.015 14.0 0.1 0.023 13.4 0.1 1.2 1 0 0 1 1 1 0 Photosystem II protein Wzy_C PF04932.15 KKK16083.1 - 4.2 7.0 8.4 11 5.7 0.1 3.1 3 0 0 3 3 3 0 O-Antigen ligase PUNUT PF16913.5 KKK16083.1 - 4.4 6.4 19.2 37 3.4 19.2 2.1 1 1 0 1 1 1 0 Purine nucleobase transmembrane transport Molybdopterin PF00384.22 KKK16084.1 - 8.6e-69 232.6 0.0 7.3e-35 120.8 0.0 2.2 1 1 1 2 2 2 2 Molybdopterin oxidoreductase NADH-G_4Fe-4S_3 PF10588.9 KKK16084.1 - 2.8e-17 61.9 0.2 2.8e-17 61.9 0.2 2.3 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Fer2_4 PF13510.6 KKK16084.1 - 1.5e-16 60.2 0.2 4.8e-16 58.6 0.2 1.9 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NADH_dhqG_C PF09326.11 KKK16084.1 - 2.2e-12 47.5 2.8 1.5e-10 41.6 0.1 2.8 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase subunit G, C-terminal Fer2 PF00111.27 KKK16084.1 - 0.00021 21.2 0.3 0.00021 21.2 0.3 2.2 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4 PF00037.27 KKK16084.1 - 0.17 11.8 1.1 4.9 7.1 0.3 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain HLH PF00010.26 KKK16085.1 - 2.3e-14 53.1 0.2 4.5e-14 52.2 0.2 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF3984 PF13136.6 KKK16090.1 - 4.2 6.7 14.1 4.2 6.7 12.3 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3984) DEAD PF00270.29 KKK16091.1 - 7e-38 130.1 0.0 2.4e-37 128.4 0.0 1.9 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KKK16091.1 - 7.2e-22 77.8 0.0 1.4e-21 76.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 KKK16091.1 - 3.4e-21 75.2 0.0 6.2e-21 74.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) AAA_22 PF13401.6 KKK16091.1 - 0.011 16.0 0.1 0.41 10.9 0.0 3.0 3 0 0 3 3 3 0 AAA domain ResIII PF04851.15 KKK16091.1 - 0.053 13.5 0.0 0.24 11.4 0.0 2.0 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit DUF1289 PF06945.13 KKK16091.1 - 0.083 12.7 1.6 0.3 10.9 1.6 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1289) UvrD-helicase PF00580.21 KKK16091.1 - 0.096 12.2 3.0 3.7 7.0 0.0 2.2 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain His_Phos_1 PF00300.22 KKK16125.1 - 4.1e-05 23.4 0.6 0.00015 21.5 0.6 2.0 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Sds3 PF08598.11 KKK16125.1 - 0.1 12.6 2.5 11 6.0 0.0 2.1 2 0 0 2 2 2 0 Sds3-like Homeodomain PF00046.29 KKK16126.1 - 7.1e-17 61.0 3.3 1.4e-16 60.1 2.4 2.0 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 KKK16126.1 - 8.8e-06 25.5 0.5 8.8e-06 25.5 0.5 2.6 2 0 0 2 2 2 1 Homeobox KN domain DUF4638 PF15472.6 KKK16126.1 - 0.026 14.3 3.8 0.05 13.3 3.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) RR_TM4-6 PF06459.12 KKK16126.1 - 1.6 8.5 16.6 2.9 7.6 16.6 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CDC45 PF02724.14 KKK16126.1 - 3.4 5.9 14.4 5 5.3 14.4 1.1 1 0 0 1 1 1 0 CDC45-like protein CRC_subunit PF08624.10 KKK16128.1 - 3.9e-51 173.0 0.0 6.1e-51 172.4 0.0 1.3 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit Flavin_Reduct PF01613.18 KKK16145.1 - 5.7e-26 91.4 0.3 2.1e-20 73.3 0.5 2.4 2 0 0 2 2 2 2 Flavin reductase like domain Vps5 PF09325.10 KKK16146.1 - 1.9e-90 302.5 2.4 1.9e-90 302.5 2.4 1.4 2 0 0 2 2 2 1 Vps5 C terminal like PX PF00787.24 KKK16146.1 - 1.3e-25 89.6 0.2 2.8e-25 88.5 0.0 1.7 2 0 0 2 2 2 1 PX domain BAR_3 PF16746.5 KKK16146.1 - 0.063 13.0 9.7 2.8 7.6 4.6 2.8 1 1 1 2 2 2 0 BAR domain of APPL family DUF3450 PF11932.8 KKK16146.1 - 0.18 11.1 8.7 0.07 12.4 5.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Calreticulin PF00262.18 KKK16148.1 - 1.2e-166 554.1 14.7 1.2e-166 554.1 14.7 1.4 2 0 0 2 2 2 1 Calreticulin family Aldolase_II PF00596.21 KKK16149.1 - 2.5e-45 154.7 0.0 3e-45 154.5 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Cyclin PF08613.11 KKK16152.1 - 1.5e-12 48.2 0.0 2e-12 47.7 0.0 1.2 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 KKK16152.1 - 5.3e-05 23.0 0.0 8.9e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain DUF1582 PF07621.11 KKK16154.1 - 0.0056 16.6 3.7 1.4 8.9 0.2 3.4 3 0 0 3 3 3 2 Protein of unknown function (DUF1582) Nodulin_late PF07127.11 KKK16154.1 - 0.019 15.3 1.7 0.019 15.3 1.7 4.8 5 0 0 5 5 5 0 Late nodulin protein Dickkopf_N PF04706.12 KKK16154.1 - 0.084 13.4 2.1 0.084 13.4 2.1 4.5 4 1 0 4 4 4 0 Dickkopf N-terminal cysteine-rich region Alpha-amylase PF00128.24 KKK16155.1 - 1.2e-110 370.3 0.9 1.9e-110 369.6 0.9 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Malt_amylase_C PF16657.5 KKK16155.1 - 7.1e-05 22.8 0.0 0.00015 21.8 0.0 1.6 1 0 0 1 1 1 1 Maltogenic Amylase, C-terminal domain hDGE_amylase PF14701.6 KKK16155.1 - 0.0033 16.6 0.0 0.0053 15.9 0.0 1.2 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain Glyco_transf_25 PF01755.17 KKK16157.1 - 0.016 15.1 0.0 1.6 8.6 0.0 2.4 2 0 0 2 2 2 0 Glycosyltransferase family 25 (LPS biosynthesis protein) Aldedh PF00171.22 KKK16158.1 - 5.4e-152 506.5 0.0 6.6e-152 506.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 KKK16158.1 - 0.17 10.9 0.1 0.27 10.2 0.1 1.2 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) Pkinase PF00069.25 KKK16180.1 - 1.3e-42 146.0 0.0 2.1e-42 145.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK16180.1 - 1.9e-16 60.1 0.0 3.1e-15 56.2 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KKK16180.1 - 0.003 16.6 0.0 0.0049 15.9 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KKK16180.1 - 0.037 13.4 0.2 0.062 12.6 0.2 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 KKK16180.1 - 0.12 11.4 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Stc1 PF12898.7 KKK16181.1 - 6.3e-18 65.1 3.8 1.1e-17 64.3 3.8 1.4 1 0 0 1 1 1 1 Stc1 domain FAM60A PF15396.6 KKK16181.1 - 0.082 12.9 1.9 0.19 11.7 1.9 1.5 1 0 0 1 1 1 0 Protein Family FAM60A zf-RING_10 PF16685.5 KKK16181.1 - 0.82 9.9 4.6 1.9 8.7 4.7 1.6 1 1 0 1 1 1 0 zinc RING finger of MSL2 Amidase PF01425.21 KKK16182.1 - 2e-62 211.6 0.0 3.5e-52 177.9 0.0 2.5 1 1 1 2 2 2 2 Amidase Fungal_trans_2 PF11951.8 KKK16182.1 - 0.0022 16.9 0.0 0.0041 16.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Stn1 PF10451.9 KKK16183.1 - 3.2e-08 32.9 0.0 5.6e-06 25.5 0.0 2.1 2 0 0 2 2 2 2 Telomere regulation protein Stn1 Herpes_UL56 PF04534.12 KKK16183.1 - 9.7 5.6 8.0 17 4.9 8.0 1.3 1 0 0 1 1 1 0 Herpesvirus UL56 protein DnaJ PF00226.31 KKK16185.1 - 9.2e-24 83.4 1.8 2.4e-23 82.0 1.8 1.8 1 0 0 1 1 1 1 DnaJ domain DUF4878 PF12870.7 KKK16185.1 - 0.13 12.6 2.8 0.52 10.6 2.8 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4878) STT3 PF02516.14 KKK16216.1 - 1.1e-145 486.3 34.4 1.6e-140 469.3 32.4 2.2 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit Dpy19 PF10034.9 KKK16216.1 - 0.024 12.9 1.1 0.032 12.4 0.0 1.8 2 1 0 2 2 2 0 Q-cell neuroblast polarisation CSN8_PSD8_EIF3K PF10075.9 KKK16217.1 - 9.9e-30 103.4 0.0 1.1e-29 103.3 0.0 1.0 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family SAC3_GANP PF03399.16 KKK16217.1 - 0.061 12.7 0.0 0.077 12.4 0.0 1.1 1 0 0 1 1 1 0 SAC3/GANP family PMT PF02366.18 KKK16218.1 - 5.8e-86 288.1 18.3 9.9e-86 287.3 18.3 1.4 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 KKK16218.1 - 3.3e-70 235.7 3.6 3.3e-70 235.7 3.6 2.9 2 1 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 KKK16218.1 - 5.9e-20 71.9 0.3 9e-20 71.3 0.3 1.2 1 0 0 1 1 1 1 MIR domain Lin-8 PF03353.15 KKK16219.1 - 0.81 9.2 4.6 1.3 8.5 4.6 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist PRKCSH PF07915.13 KKK16220.1 - 1.8e-20 73.7 0.2 4.6e-20 72.4 0.2 1.8 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.6 KKK16220.1 - 0.014 15.1 0.2 0.21 11.3 0.2 2.2 1 1 0 1 1 1 0 Glucosidase II beta subunit-like protein Rota_NSP3 PF01665.16 KKK16220.1 - 0.079 12.1 0.5 0.12 11.4 0.5 1.2 1 0 0 1 1 1 0 Rotavirus non-structural protein NSP3 RasGAP PF00616.19 KKK16220.1 - 0.2 11.3 0.7 0.43 10.3 0.7 1.5 1 0 0 1 1 1 0 GTPase-activator protein for Ras-like GTPase Pirin PF02678.16 KKK16221.1 - 1.6e-28 98.8 0.2 3.3e-28 97.8 0.2 1.5 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.13 KKK16221.1 - 7.9e-24 84.0 0.0 3.2e-23 82.1 0.0 1.9 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.11 KKK16221.1 - 5.3e-05 22.9 2.1 0.00012 21.7 1.2 2.1 2 0 0 2 2 2 1 Cupin domain Cupin_3 PF05899.12 KKK16221.1 - 0.14 11.9 0.2 0.41 10.4 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF861) APH PF01636.23 KKK16222.1 - 3.2e-14 53.4 0.0 1.2e-13 51.6 0.0 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 KKK16222.1 - 0.0055 15.6 0.0 0.18 10.7 0.1 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1679) Coiled-coil_56 PF09813.9 KKK16223.1 - 5.7e-05 23.1 0.0 6.3e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 56 MFS_1 PF07690.16 KKK16224.1 - 1.8e-34 119.2 34.9 2.1e-34 119.0 34.9 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KKK16224.1 - 1.7e-06 27.2 22.1 5.6e-06 25.5 22.1 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter Trp_oprn_chp PF09534.10 KKK16224.1 - 0.65 9.8 8.1 0.5 10.1 0.3 2.2 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF3453 PF11935.8 KKK16225.1 - 1.8e-74 250.2 1.0 3.7e-74 249.2 0.6 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3453) RNA_pol_Rbc25 PF08292.12 KKK16226.1 - 3.1e-35 121.2 1.1 2.3e-34 118.4 1.1 2.0 1 1 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.17 KKK16226.1 - 1.1e-14 54.6 0.0 1.8e-14 53.8 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 Cys_Met_Meta_PP PF01053.20 KKK16227.1 - 1.1e-142 475.1 0.1 1.3e-142 474.9 0.1 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 KKK16227.1 - 3.1e-08 33.2 0.2 5.7e-08 32.3 0.2 1.4 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KKK16227.1 - 2.4e-07 30.1 0.5 4.3e-07 29.2 0.5 1.4 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 KKK16227.1 - 1.7e-06 27.6 0.4 2.9e-06 26.8 0.4 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 KKK16227.1 - 0.0017 17.7 0.1 0.0041 16.5 0.1 1.7 1 1 0 1 1 1 1 Beta-eliminating lyase Asp_Arg_Hydrox PF05118.15 KKK16227.1 - 0.075 12.8 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 Aspartyl/Asparaginyl beta-hydroxylase RRM_1 PF00076.22 KKK16228.1 - 3.4e-09 36.4 0.1 1.5e-05 24.8 0.0 3.0 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sds3 PF08598.11 KKK16229.1 - 6.6e-19 68.8 0.0 1.3e-18 67.9 0.0 1.6 1 0 0 1 1 1 1 Sds3-like DUF1487 PF07368.11 KKK16229.1 - 0.029 13.8 0.4 1.8 7.9 0.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1487) ATP-synt_E PF05680.12 KKK16230.1 - 1.1e-20 73.7 0.3 1.3e-20 73.6 0.3 1.0 1 0 0 1 1 1 1 ATP synthase E chain YqjK PF13997.6 KKK16230.1 - 0.013 15.7 0.6 0.76 10.1 0.2 2.1 2 0 0 2 2 2 0 YqjK-like protein UCR_14kD PF02271.16 KKK16230.1 - 0.056 13.4 0.0 0.062 13.3 0.0 1.1 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase complex 14kD subunit Adhesin_P1_N PF18652.1 KKK16230.1 - 2.2 8.4 7.0 2.8 8.0 2.9 2.5 1 1 1 2 2 2 0 Adhesin P1 N-terminal domain WD40 PF00400.32 KKK16231.1 - 2.6e-05 24.9 7.3 3.7 8.6 0.1 5.8 5 1 0 5 5 5 3 WD domain, G-beta repeat DNA_pol_phi PF04931.13 KKK16231.1 - 0.19 9.8 5.4 0.27 9.3 5.4 1.1 1 0 0 1 1 1 0 DNA polymerase phi GPI-anchored PF10342.9 KKK16232.1 - 3.7e-21 75.7 2.8 3.7e-21 75.7 2.8 2.7 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family SOG2 PF10428.9 KKK16232.1 - 0.53 9.4 18.9 0.62 9.2 18.9 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Tmemb_cc2 PF10267.9 KKK16232.1 - 1.3 8.1 3.6 1.4 8.0 3.6 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Plasmodium_Vir PF05795.11 KKK16232.1 - 2.4 7.5 3.9 2.7 7.3 3.9 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Macoilin PF09726.9 KKK16232.1 - 6 5.3 8.4 6.5 5.2 8.4 1.0 1 0 0 1 1 1 0 Macoilin family SR-25 PF10500.9 KKK16232.1 - 9.1 5.8 15.2 28 4.2 15.8 1.5 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Apt1 PF10351.9 KKK16232.1 - 9.4 5.0 8.7 11 4.7 8.7 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Hamartin PF04388.12 KKK16232.1 - 9.6 4.7 11.4 9.6 4.7 11.4 1.1 1 0 0 1 1 1 0 Hamartin protein NUFIP1 PF10453.9 KKK16233.1 - 8.5e-16 57.5 2.9 8.5e-16 57.5 2.9 3.0 2 0 0 2 2 2 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) zf-CCCH PF00642.24 KKK16233.1 - 1.8e-07 30.9 2.6 3.3e-07 30.1 2.6 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 KKK16233.1 - 6e-06 25.9 3.6 1e-05 25.2 3.6 1.4 1 0 0 1 1 1 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 KKK16233.1 - 1.8e-05 24.6 6.4 3e-05 23.9 6.4 1.3 1 0 0 1 1 1 1 Zinc finger domain Torus PF16131.5 KKK16233.1 - 0.00071 20.2 0.0 0.00071 20.2 0.0 3.4 3 0 0 3 3 3 1 Torus domain DUF3584 PF12128.8 KKK16233.1 - 3.3 5.1 21.0 4.4 4.7 21.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Pyr_redox_2 PF07992.14 KKK16235.1 - 1.2e-06 28.0 0.1 4.4e-06 26.2 0.1 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KKK16235.1 - 1.3e-05 25.2 0.3 0.0021 18.1 0.5 3.0 2 1 0 2 2 2 1 FAD-NAD(P)-binding K_oxygenase PF13434.6 KKK16235.1 - 0.00094 18.4 0.0 0.013 14.6 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 KKK16235.1 - 0.065 12.5 0.2 8.1 5.6 0.8 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase PAP2_3 PF14378.6 KKK16236.1 - 9.3e-34 116.8 13.2 1.3e-15 57.6 0.1 3.4 3 0 0 3 3 3 3 PAP2 superfamily PAP2 PF01569.21 KKK16236.1 - 0.002 17.9 3.6 0.0069 16.1 1.1 2.4 1 1 0 2 2 2 1 PAP2 superfamily Fungal_trans PF04082.18 KKK16237.1 - 5.6e-14 51.8 0.0 9.2e-14 51.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK16237.1 - 4e-06 26.8 13.5 8.4e-06 25.8 13.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Methyltransf_16 PF10294.9 KKK16239.1 - 5.3e-06 26.3 0.0 0.00047 19.9 0.0 2.2 2 0 0 2 2 2 2 Lysine methyltransferase TRAP_alpha PF03896.16 KKK16239.1 - 0.035 13.3 0.1 0.053 12.7 0.1 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit SHD1 PF03983.12 KKK16240.1 - 5.1e-34 115.9 0.0 9.1e-34 115.1 0.0 1.4 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_1 PF00018.28 KKK16240.1 - 2e-33 113.7 5.7 1.4e-11 43.8 0.1 4.3 4 0 0 4 4 4 3 SH3 domain SH3_9 PF14604.6 KKK16240.1 - 1.5e-29 101.6 10.4 6.7e-13 48.3 0.2 4.1 5 0 0 5 5 5 3 Variant SH3 domain SH3_2 PF07653.17 KKK16240.1 - 4.3e-20 71.1 0.2 3.9e-08 32.8 0.0 4.4 4 0 0 4 4 4 4 Variant SH3 domain DUF1720 PF08226.11 KKK16240.1 - 1.2e-08 35.2 33.6 1.2e-08 35.2 33.6 6.9 1 1 3 4 4 4 2 Domain of unknown function (DUF1720) SAM_4 PF18017.1 KKK16240.1 - 0.00047 20.1 0.0 0.001 19.0 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_10 PF17902.1 KKK16240.1 - 0.0026 17.8 0.1 1.3 9.2 0.0 3.4 3 0 0 3 3 3 1 SH3 domain SH3_3 PF08239.11 KKK16240.1 - 0.017 15.4 4.5 0.48 10.8 0.8 2.7 2 0 0 2 2 2 0 Bacterial SH3 domain SIN1_PH PF16979.5 KKK16240.1 - 0.12 12.6 0.1 22 5.4 0.1 3.2 2 1 0 2 2 2 0 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology Ank_2 PF12796.7 KKK16242.1 - 1.8e-40 137.4 4.7 8.3e-10 39.1 0.1 5.3 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KKK16242.1 - 3.2e-38 129.6 9.9 4e-08 33.6 0.0 9.8 5 3 5 10 10 10 6 Ankyrin repeats (many copies) Ank PF00023.30 KKK16242.1 - 1.3e-35 120.3 3.7 8.9e-05 22.8 0.0 9.2 9 0 0 9 9 9 7 Ankyrin repeat Ank_3 PF13606.6 KKK16242.1 - 2.9e-33 110.2 5.3 0.00058 20.1 0.0 10.9 12 1 0 12 12 12 7 Ankyrin repeat Ank_5 PF13857.6 KKK16242.1 - 8.4e-27 92.9 12.4 4.1e-07 30.1 0.1 8.7 5 3 3 8 8 8 7 Ankyrin repeats (many copies) AnkUBD PF18418.1 KKK16242.1 - 0.01 16.0 0.1 2.1 8.5 0.0 3.1 1 1 1 2 2 2 0 Ankyrin ubiquitin-binding domain NOA36 PF06524.12 KKK16242.1 - 2 7.6 3.3 3 7.1 3.3 1.1 1 0 0 1 1 1 0 NOA36 protein Ank_4 PF13637.6 KKK16243.1 - 9.2e-10 38.9 0.2 3.2e-05 24.4 0.1 3.1 1 1 2 3 3 3 2 Ankyrin repeats (many copies) NACHT PF05729.12 KKK16243.1 - 1.4e-09 38.1 0.0 4.9e-09 36.3 0.0 1.9 2 0 0 2 2 2 1 NACHT domain Ank PF00023.30 KKK16243.1 - 8.8e-09 35.4 0.1 0.00033 20.9 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat AAA_22 PF13401.6 KKK16243.1 - 1.2e-08 35.4 0.1 3.3e-08 33.9 0.1 1.7 1 0 0 1 1 1 1 AAA domain Ank_2 PF12796.7 KKK16243.1 - 1.3e-07 32.1 0.0 3.5e-07 30.7 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) AAA_16 PF13191.6 KKK16243.1 - 2.8e-06 27.8 0.1 1.1e-05 26.0 0.1 2.0 1 0 0 1 1 1 1 AAA ATPase domain Ank_3 PF13606.6 KKK16243.1 - 8.3e-06 25.8 0.0 0.00012 22.2 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 KKK16243.1 - 0.00048 20.4 0.0 0.0026 18.0 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (many copies) AAA_33 PF13671.6 KKK16243.1 - 0.013 15.6 0.0 0.035 14.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 KKK16243.1 - 0.019 14.1 0.5 0.12 11.5 0.0 2.1 1 1 1 2 2 2 0 NB-ARC domain AAA PF00004.29 KKK16243.1 - 0.042 14.3 0.0 0.13 12.7 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 KKK16243.1 - 0.073 13.1 0.1 1.3 9.0 0.1 2.5 1 1 0 1 1 1 0 AAA domain Torsin PF06309.11 KKK16243.1 - 0.077 13.1 0.0 0.19 11.9 0.0 1.6 1 0 0 1 1 1 0 Torsin ResIII PF04851.15 KKK16243.1 - 0.1 12.6 0.0 0.22 11.5 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit SAM_2 PF07647.17 KKK16246.1 - 2.9e-11 43.3 0.1 5.6e-11 42.4 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KKK16246.1 - 6.3e-09 36.1 0.2 1.8e-08 34.7 0.2 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH PF00169.29 KKK16246.1 - 1.4e-08 35.2 0.1 5.7e-08 33.2 0.0 2.1 2 0 0 2 2 2 1 PH domain SAM_3 PF18016.1 KKK16246.1 - 6.3e-05 22.7 0.0 0.00017 21.3 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_Ste50p PF09235.10 KKK16246.1 - 0.00017 21.8 0.0 0.00035 20.7 0.0 1.5 1 0 0 1 1 1 1 Ste50p, sterile alpha motif SAM_PNT PF02198.16 KKK16246.1 - 0.0038 17.2 0.1 0.0098 15.8 0.0 1.7 2 0 0 2 2 2 1 Sterile alpha motif (SAM)/Pointed domain Fungal_trans_2 PF11951.8 KKK16247.1 - 1.1e-87 294.4 0.2 1.3e-87 294.2 0.2 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain Init_tRNA_PT PF04179.12 KKK16247.1 - 0.091 13.1 0.0 0.21 11.9 0.0 1.5 1 0 0 1 1 1 0 Rit1 DUSP-like domain NUDE_C PF04880.13 KKK16247.1 - 1.6 9.2 7.8 3.2 8.2 7.8 1.4 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region ASFV_J13L PF05568.11 KKK16247.1 - 2.2 8.0 15.3 3.9 7.2 15.3 1.3 1 0 0 1 1 1 0 African swine fever virus J13L protein PH_10 PF15411.6 KKK16248.1 - 2.7e-28 98.7 0.2 4.9e-28 97.9 0.2 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain VWA PF00092.28 KKK16248.1 - 1.5e-13 51.4 0.0 2.6e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 KKK16248.1 - 2.9e-10 40.3 0.0 1.6e-09 37.9 0.0 2.3 2 1 0 2 2 2 1 von Willebrand factor type A domain zf-RING_2 PF13639.6 KKK16248.1 - 0.00024 21.4 4.1 0.00043 20.6 4.1 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 KKK16248.1 - 0.00048 20.0 4.2 0.00083 19.3 4.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KKK16248.1 - 0.0037 17.1 4.0 0.0067 16.2 4.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KKK16248.1 - 0.0075 16.1 4.2 0.013 15.3 4.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 KKK16248.1 - 0.0086 15.7 3.3 0.0086 15.7 3.3 1.9 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-RING-like PF08746.11 KKK16248.1 - 0.018 15.3 4.3 0.034 14.4 4.3 1.4 1 0 0 1 1 1 0 RING-like domain zf-rbx1 PF12678.7 KKK16248.1 - 0.052 13.8 1.9 0.11 12.8 1.9 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-UDP PF14569.6 KKK16248.1 - 0.11 12.6 0.8 0.2 11.8 0.8 1.3 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-RING_11 PF17123.5 KKK16248.1 - 0.52 10.1 3.3 1 9.1 3.3 1.5 1 0 0 1 1 1 0 RING-like zinc finger zf-C3H2C3 PF17122.5 KKK16248.1 - 0.61 10.2 4.7 1.3 9.1 4.7 1.6 1 0 0 1 1 1 0 Zinc-finger Ribosomal_S17e PF00833.18 KKK16265.1 - 3.7e-37 126.9 0.1 3.8e-37 126.9 0.1 1.0 1 0 0 1 1 1 1 Ribosomal S17 GMC_oxred_N PF00732.19 KKK16266.1 - 1.8e-61 208.1 0.0 2.5e-61 207.7 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KKK16266.1 - 2.9e-36 125.1 0.1 5.5e-36 124.2 0.1 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KKK16266.1 - 3e-07 29.9 0.0 0.0091 15.1 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 KKK16266.1 - 0.0017 18.0 0.3 0.083 12.5 0.1 2.9 3 1 0 3 3 3 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KKK16266.1 - 0.012 14.7 0.0 0.017 14.2 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Thi4 PF01946.17 KKK16266.1 - 0.014 14.7 0.1 0.032 13.5 0.1 1.5 1 0 0 1 1 1 0 Thi4 family NAD_binding_8 PF13450.6 KKK16266.1 - 0.035 14.3 0.1 0.11 12.7 0.1 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KKK16266.1 - 0.056 14.0 0.0 9 6.9 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase MFS_1 PF07690.16 KKK16267.1 - 2.3e-42 145.2 44.8 2.3e-42 145.2 44.8 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KKK16267.1 - 1.2e-08 34.3 12.9 1.2e-08 34.3 12.9 2.3 2 1 0 2 2 2 1 Sugar (and other) transporter Abhydrolase_3 PF07859.13 KKK16268.1 - 4.2e-23 82.3 0.1 6.3e-23 81.7 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KKK16268.1 - 1.6e-17 63.4 0.0 2.2e-17 63.0 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 KKK16268.1 - 0.033 13.7 0.0 0.12 11.8 0.0 1.8 2 0 0 2 2 2 0 Prolyl oligopeptidase family zf-CCCH PF00642.24 KKK16269.1 - 0.0004 20.2 18.4 0.0007 19.4 1.0 3.8 4 0 0 4 4 4 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KKK16269.1 - 0.00093 19.2 4.7 0.00093 19.2 4.7 4.2 4 0 0 4 4 4 1 Zinc finger domain Torus PF16131.5 KKK16269.1 - 0.0022 18.7 0.1 0.0022 18.7 0.1 2.7 3 0 0 3 3 3 1 Torus domain zf-CCCH_4 PF18044.1 KKK16269.1 - 0.0067 16.2 1.9 0.0067 16.2 1.9 4.3 4 1 0 4 4 4 1 CCCH-type zinc finger SHE3 PF17078.5 KKK16269.1 - 0.087 12.5 1.1 0.13 12.0 1.1 1.2 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 Dor1 PF04124.12 KKK16269.1 - 0.13 11.0 0.3 0.19 10.3 0.3 1.1 1 0 0 1 1 1 0 Dor1-like family CENP-Q PF13094.6 KKK16269.1 - 2.2 8.5 4.7 6 7.0 3.9 1.9 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit ketoacyl-synt PF00109.26 KKK16270.1 - 1.7e-66 224.4 0.0 3.8e-66 223.3 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 KKK16270.1 - 2.6e-63 213.2 0.3 5.2e-63 212.2 0.3 1.6 1 0 0 1 1 1 1 KR domain PS-DH PF14765.6 KKK16270.1 - 8.6e-61 205.8 0.0 1.3e-60 205.1 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 KKK16270.1 - 1.2e-50 172.8 0.6 5.5e-50 170.7 0.0 2.3 3 0 0 3 3 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KKK16270.1 - 9.9e-39 132.0 0.0 2.6e-38 130.7 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 KKK16270.1 - 1.4e-15 57.7 0.0 4e-15 56.2 0.0 1.9 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension adh_short PF00106.25 KKK16270.1 - 1.3e-13 50.9 0.1 4.3e-13 49.1 0.1 1.9 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KKK16270.1 - 1.1e-10 41.5 0.1 2.8e-10 40.1 0.1 1.7 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Methyltransf_31 PF13847.6 KKK16270.1 - 1.7e-07 31.2 0.0 4.7e-07 29.7 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.26 KKK16270.1 - 4.9e-07 29.8 0.0 1.7e-06 28.0 0.0 2.0 2 0 0 2 2 1 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.6 KKK16270.1 - 7.3e-07 29.2 0.0 2e-06 27.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.25 KKK16270.1 - 6.7e-05 23.2 0.0 0.00021 21.6 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_12 PF08242.12 KKK16270.1 - 0.00021 22.0 0.0 0.00067 20.4 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.23 KKK16270.1 - 0.00043 19.7 0.1 0.00094 18.6 0.1 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_11 PF08241.12 KKK16270.1 - 0.0008 20.0 0.0 0.0032 18.1 0.0 2.1 2 0 0 2 2 1 1 Methyltransferase domain SAT PF16073.5 KKK16270.1 - 0.0042 16.8 0.5 0.01 15.6 0.5 1.6 1 0 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis ADH_N PF08240.12 KKK16270.1 - 0.0055 16.6 0.0 0.018 14.9 0.0 1.9 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Ubie_methyltran PF01209.18 KKK16270.1 - 0.0075 15.6 0.0 0.015 14.7 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 KKK16270.1 - 0.0084 16.8 0.0 0.049 14.3 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_16 PF10294.9 KKK16270.1 - 0.034 13.9 0.0 0.11 12.2 0.0 1.8 2 0 0 2 2 2 0 Lysine methyltransferase GDP_Man_Dehyd PF16363.5 KKK16270.1 - 0.084 12.2 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase ThrE PF06738.12 KKK16271.1 - 1.4e-76 257.0 15.9 3.8e-69 232.7 2.9 2.4 2 0 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 KKK16271.1 - 3e-13 50.0 10.9 3e-13 50.0 10.9 2.8 3 1 0 3 3 3 1 Threonine/Serine exporter, ThrE ABC2_membrane PF01061.24 KKK16272.1 - 4.1e-85 284.5 44.5 1.2e-47 162.1 18.2 2.5 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 KKK16272.1 - 8.3e-39 133.2 0.0 2.4e-18 67.0 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 KKK16272.1 - 1.3e-28 98.7 6.5 8.6e-27 92.9 0.0 3.6 3 0 0 3 3 3 2 CDR ABC transporter AAA_16 PF13191.6 KKK16272.1 - 6.7e-06 26.6 0.1 0.0098 16.3 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain ABC_trans_N PF14510.6 KKK16272.1 - 9.8e-06 26.1 0.1 2.4e-05 24.9 0.1 1.6 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_22 PF13401.6 KKK16272.1 - 9.4e-05 22.7 0.0 0.94 9.7 0.0 3.0 2 0 0 2 2 2 2 AAA domain ABC2_membrane_3 PF12698.7 KKK16272.1 - 0.00019 20.7 37.6 0.021 13.9 17.4 2.5 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_25 PF13481.6 KKK16272.1 - 0.00068 19.3 0.1 0.025 14.1 0.1 2.3 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KKK16272.1 - 0.00072 19.3 0.4 0.089 12.6 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_33 PF13671.6 KKK16272.1 - 0.00073 19.7 0.0 1.2 9.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 KKK16272.1 - 0.00099 19.0 0.0 0.016 15.1 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_28 PF13521.6 KKK16272.1 - 0.0016 18.7 0.4 0.97 9.7 0.4 2.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KKK16272.1 - 0.0018 18.8 0.0 1.9 9.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain PduV-EutP PF10662.9 KKK16272.1 - 0.0034 17.1 0.7 1.3 8.8 0.0 2.4 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation cobW PF02492.19 KKK16272.1 - 0.011 15.3 1.7 1.8 8.1 0.4 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.6 KKK16272.1 - 0.031 14.7 0.3 2.5 8.5 0.0 2.8 3 0 0 3 3 2 0 AAA domain NACHT PF05729.12 KKK16272.1 - 0.04 13.8 1.2 3.6 7.5 0.1 2.4 2 0 0 2 2 2 0 NACHT domain AAA PF00004.29 KKK16272.1 - 0.088 13.2 0.1 14 6.1 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 KKK16272.1 - 0.097 12.4 0.4 6 6.5 0.2 2.3 2 0 0 2 2 2 0 AAA domain CorA PF01544.18 KKK16273.1 - 6.3e-07 29.0 5.1 1.1e-06 28.2 5.1 1.5 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Pkinase_fungal PF17667.1 KKK16275.1 - 2.3e-133 444.9 0.1 2.9e-133 444.6 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 KKK16275.1 - 0.00075 19.2 0.4 0.0025 17.5 0.0 2.1 3 0 0 3 3 3 1 Kinetochore Sim4 complex subunit FTA2 MauJ PF17419.2 KKK16275.1 - 0.012 15.2 0.0 0.021 14.3 0.0 1.3 1 0 0 1 1 1 0 Methylamine utilization protein MauJ Xan_ur_permease PF00860.20 KKK16276.1 - 4.2e-23 81.7 30.8 1.4e-14 53.6 14.1 2.9 3 0 0 3 3 3 2 Permease family Zn_clus PF00172.18 KKK16277.1 - 1.5e-07 31.4 9.1 3.2e-07 30.4 9.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KKK16301.1 - 4.3e-15 55.5 0.0 9.6e-15 54.3 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK16301.1 - 3.7e-07 30.2 12.1 6.4e-07 29.4 12.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FCH PF00611.23 KKK16302.1 - 1.4e-14 54.1 0.0 8.9e-14 51.5 0.0 2.4 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.28 KKK16302.1 - 5.6e-12 45.1 0.0 1.3e-11 43.9 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KKK16302.1 - 6.4e-11 41.9 0.0 1.4e-10 40.9 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KKK16302.1 - 2.8e-10 39.7 0.0 1.1e-09 37.8 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain Transcrip_act PF04949.13 KKK16302.1 - 0.13 12.1 1.5 9.9 6.0 0.1 2.3 2 0 0 2 2 2 0 Transcriptional activator Rapsyn_N PF10579.9 KKK16302.1 - 0.14 12.3 0.1 0.3 11.2 0.1 1.5 1 0 0 1 1 1 0 Rapsyn N-terminal myristoylation and linker region Not1 PF04054.15 KKK16303.1 - 3.1e-141 470.6 0.1 6.6e-141 469.5 0.1 1.6 1 0 0 1 1 1 1 CCR4-Not complex component, Not1 CNOT1_CAF1_bind PF16415.5 KKK16303.1 - 9.4e-96 319.5 0.4 2.3e-95 318.3 0.4 1.7 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain DUF3819 PF12842.7 KKK16303.1 - 1.7e-52 177.3 2.7 1e-51 174.8 1.4 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3819) CNOT1_TTP_bind PF16417.5 KKK16303.1 - 1.9e-40 138.0 0.0 5.9e-40 136.5 0.0 1.8 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 TTP binding domain CNOT1_HEAT PF16418.5 KKK16303.1 - 1.3e-31 109.7 0.0 6.6e-31 107.4 0.0 2.3 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 1 HEAT repeat Seipin PF06775.14 KKK16304.1 - 2.5e-62 210.5 2.4 3.7e-62 209.9 2.4 1.2 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) Trypan_PARP PF05887.11 KKK16304.1 - 0.14 12.1 2.9 0.22 11.5 2.9 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) TTL PF03133.15 KKK16305.1 - 9.9e-56 189.0 0.0 1.5e-55 188.4 0.0 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family SurE PF01975.17 KKK16305.1 - 3e-50 170.7 0.0 4.4e-50 170.2 0.0 1.2 1 0 0 1 1 1 1 Survival protein SurE ATPgrasp_YheCD PF14398.6 KKK16305.1 - 4e-05 23.0 0.0 0.00012 21.4 0.0 1.7 2 0 0 2 2 2 1 YheC/D like ATP-grasp Dala_Dala_lig_C PF07478.13 KKK16305.1 - 0.1 12.1 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus Methyltransf_23 PF13489.6 KKK16307.1 - 7.2e-40 136.5 0.0 9.5e-40 136.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKK16307.1 - 2.6e-08 34.4 0.0 9.4e-07 29.5 0.0 2.9 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KKK16307.1 - 1.4e-06 28.9 0.0 4.5e-06 27.3 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KKK16307.1 - 5.9e-06 26.9 0.0 0.00013 22.6 0.0 2.6 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KKK16307.1 - 0.0039 17.0 0.0 0.023 14.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Pex14_N PF04695.13 KKK16308.1 - 2.5e-43 148.5 0.2 2.5e-43 148.5 0.2 4.5 3 2 0 4 4 4 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF1043 PF06295.12 KKK16308.1 - 0.0087 16.1 1.1 0.28 11.2 0.3 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1043) Baculo_PEP_C PF04513.12 KKK16308.1 - 0.18 11.8 2.6 0.63 10.1 2.7 1.8 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus CENP-B_dimeris PF09026.10 KKK16308.1 - 0.56 10.6 15.6 1.7 9.1 15.6 1.8 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Golgin_A5 PF09787.9 KKK16308.1 - 2.4 7.6 19.6 0.023 14.2 1.1 3.0 3 0 0 3 3 3 0 Golgin subfamily A member 5 Ndc80_HEC PF03801.13 KKK16309.1 - 9.9e-60 200.6 0.3 2.8e-59 199.1 0.0 1.9 2 0 0 2 2 2 1 HEC/Ndc80p family DUF16 PF01519.16 KKK16309.1 - 0.0036 17.8 7.4 0.0036 17.8 7.4 4.0 2 2 1 3 3 3 1 Protein of unknown function DUF16 DUF3818 PF12825.7 KKK16309.1 - 0.058 12.4 19.0 0.069 12.2 4.4 2.3 2 0 0 2 2 2 0 Domain of unknown function in PX-proteins (DUF3818) Filament PF00038.21 KKK16309.1 - 0.078 12.6 47.9 0.2 11.2 22.7 2.8 2 1 0 2 2 2 0 Intermediate filament protein NPV_P10 PF05531.12 KKK16309.1 - 2.5 8.6 14.7 4.1 7.9 0.4 4.4 2 2 2 4 4 4 0 Nucleopolyhedrovirus P10 protein Spc7 PF08317.11 KKK16309.1 - 2.6 6.8 47.8 1.2 8.0 19.7 3.1 2 2 0 2 2 2 0 Spc7 kinetochore protein Cep57_CLD PF14073.6 KKK16309.1 - 4.2 7.4 41.8 0.27 11.3 19.7 2.5 2 0 0 2 2 2 0 Centrosome localisation domain of Cep57 Prominin PF05478.11 KKK16309.1 - 5.7 4.8 24.0 0.19 9.7 6.8 2.5 2 1 0 2 2 2 0 Prominin TraF_2 PF13729.6 KKK16309.1 - 7.7 5.8 9.0 0.55 9.6 0.8 2.7 2 1 1 3 3 3 0 F plasmid transfer operon, TraF, protein zf-primase PF09329.11 KKK16311.1 - 7.8e-19 67.2 1.3 1.3e-18 66.5 1.3 1.4 1 0 0 1 1 1 1 Primase zinc finger RNase_H2-Ydr279 PF09468.10 KKK16312.1 - 5.4e-42 143.7 1.5 1.3e-41 142.4 1.5 1.7 1 1 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) wHTH domain Ydr279_N PF17745.1 KKK16312.1 - 5.8e-23 81.0 1.7 9.3e-23 80.3 0.1 2.2 2 0 0 2 2 2 1 Ydr279p protein triple barrel domain CPSF100_C PF13299.6 KKK16312.1 - 8.2 6.6 10.3 14 5.8 4.2 2.2 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal GalKase_gal_bdg PF10509.9 KKK16313.1 - 2.2e-19 68.8 0.0 4e-19 67.9 0.0 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.26 KKK16313.1 - 6.6e-15 55.1 1.1 1.4e-14 54.0 1.1 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KKK16313.1 - 9.8e-13 48.3 0.0 2.3e-12 47.1 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal HTH_37 PF13744.6 KKK16313.1 - 0.051 13.5 0.2 0.26 11.3 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_3 PF01381.22 KKK16313.1 - 0.15 12.2 0.2 0.77 9.9 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix TPP_enzyme_N PF02776.18 KKK16314.1 - 1.2e-55 187.8 0.0 4.5e-54 182.6 0.0 2.5 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 KKK16314.1 - 1e-49 168.2 0.1 1.5e-47 161.2 0.0 3.1 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 KKK16314.1 - 3.2e-38 130.5 0.1 5.5e-38 129.8 0.1 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain POR_N PF01855.19 KKK16314.1 - 0.081 12.7 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg MRP-L28 PF09812.9 KKK16315.1 - 1.3e-05 25.4 0.1 2.1e-05 24.7 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 RINGv PF12906.7 KKK16315.1 - 7.2e-05 22.8 7.3 0.00013 22.0 7.3 1.4 1 0 0 1 1 1 1 RING-variant domain FANCL_C PF11793.8 KKK16315.1 - 0.00019 21.5 3.3 0.00037 20.6 3.3 1.4 1 0 0 1 1 1 1 FANCL C-terminal domain zf-RING_2 PF13639.6 KKK16315.1 - 0.26 11.7 6.1 0.49 10.8 6.1 1.5 1 0 0 1 1 1 0 Ring finger domain MGC-24 PF05283.11 KKK16316.1 - 0.051 14.0 8.4 0.072 13.5 8.4 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DASH_Duo1 PF08651.10 KKK16317.1 - 9.9e-28 95.7 3.4 9.9e-28 95.7 3.4 1.8 2 0 0 2 2 2 1 DASH complex subunit Duo1 ALMT PF11744.8 KKK16317.1 - 5.6 5.7 10.0 8.6 5.1 10.0 1.4 1 0 0 1 1 1 0 Aluminium activated malate transporter Dor1 PF04124.12 KKK16318.1 - 5.7e-52 176.5 3.5 5.1e-41 140.5 4.1 2.3 2 0 0 2 2 2 2 Dor1-like family Vps51 PF08700.11 KKK16318.1 - 0.0002 21.4 0.5 0.0002 21.4 0.5 2.1 2 0 0 2 2 2 1 Vps51/Vps67 COG2 PF06148.11 KKK16318.1 - 0.062 13.4 1.7 0.14 12.3 0.8 2.0 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 EAF PF09816.9 KKK16319.1 - 6.8e-19 68.1 0.3 1.7e-18 66.9 0.3 1.7 1 0 0 1 1 1 1 RNA polymerase II transcription elongation factor Cyclin_N PF00134.23 KKK16319.1 - 2.2e-14 53.3 0.1 5.6e-14 52.0 0.1 1.7 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KKK16319.1 - 0.00011 22.3 4.1 0.0014 18.7 0.0 3.6 3 1 1 4 4 4 1 Cyclin, C-terminal domain TFIIB PF00382.19 KKK16319.1 - 0.0046 17.0 3.3 0.38 10.8 0.0 2.5 2 0 0 2 2 2 2 Transcription factor TFIIB repeat His_Phos_1 PF00300.22 KKK16320.1 - 5.6e-28 97.9 1.2 6.7e-28 97.7 0.0 1.7 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) TBP PF00352.21 KKK16321.1 - 1.4e-67 223.6 0.1 9.7e-33 112.0 0.1 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 KKK16321.1 - 6.8e-05 22.9 0.0 0.23 11.6 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) DUF4295 PF14128.6 KKK16321.1 - 0.14 12.0 0.1 0.71 9.7 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4295) DAO PF01266.24 KKK16322.1 - 2.3e-46 159.0 0.2 2.8e-46 158.7 0.2 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KKK16322.1 - 3.1e-08 33.2 0.0 0.004 16.4 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KKK16322.1 - 6.9e-07 28.7 0.0 3.6e-06 26.3 0.0 1.9 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_9 PF13454.6 KKK16322.1 - 1.1e-06 28.7 0.2 0.019 15.0 0.2 2.6 2 0 0 2 2 2 2 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 KKK16322.1 - 1.3e-06 27.7 0.0 0.0049 16.0 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein FAD_binding_2 PF00890.24 KKK16322.1 - 2.5e-05 23.6 0.0 0.032 13.3 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain Trp_halogenase PF04820.14 KKK16322.1 - 4.4e-05 22.5 0.0 0.1 11.4 0.0 2.2 2 0 0 2 2 2 2 Tryptophan halogenase NAD_binding_8 PF13450.6 KKK16322.1 - 0.00011 22.3 0.0 0.00034 20.8 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KKK16322.1 - 0.001 19.6 0.0 0.023 15.2 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KKK16322.1 - 0.003 16.9 0.0 0.51 9.6 0.0 2.3 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Thi4 PF01946.17 KKK16322.1 - 0.0097 15.2 0.0 0.021 14.0 0.0 1.5 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 KKK16322.1 - 0.024 13.4 0.1 5.3 5.6 0.1 2.2 2 0 0 2 2 2 0 HI0933-like protein GMC_oxred_N PF00732.19 KKK16322.1 - 0.029 13.7 0.0 0.21 10.9 0.0 2.0 2 0 0 2 2 2 0 GMC oxidoreductase FAD_binding_3 PF01494.19 KKK16322.1 - 0.068 12.4 0.1 1.1 8.4 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain Sporozoite_P67 PF05642.11 KKK16322.1 - 0.69 7.9 2.2 0.26 9.3 0.2 1.4 2 0 0 2 2 2 0 Sporozoite P67 surface antigen DUF3439 PF11921.8 KKK16322.1 - 2.2 8.2 8.5 4.2 7.4 8.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) FolB PF02152.18 KKK16323.1 - 2e-26 92.7 0.1 1.2e-22 80.6 0.2 2.4 2 0 0 2 2 2 2 Dihydroneopterin aldolase ETF_QO PF05187.13 KKK16324.1 - 5.2e-30 103.6 0.1 9.1e-30 102.9 0.1 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S RRM_1 PF00076.22 KKK16324.1 - 8.5e-18 64.0 0.0 1.2e-07 31.5 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DAO PF01266.24 KKK16324.1 - 7.8e-08 32.3 0.2 0.00061 19.5 0.4 2.3 1 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KKK16324.1 - 1.5e-07 31.5 0.0 6.3e-07 29.5 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KKK16324.1 - 4.4e-07 29.3 0.3 0.0069 15.5 0.9 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 KKK16324.1 - 2.2e-05 23.8 0.0 7.2e-05 22.2 0.0 1.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KKK16324.1 - 0.0004 19.2 0.4 0.00067 18.5 0.4 1.3 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.17 KKK16324.1 - 0.00043 19.6 0.0 0.02 14.1 0.0 2.1 2 0 0 2 2 2 1 Thi4 family FAD_oxidored PF12831.7 KKK16324.1 - 0.00044 19.7 0.0 0.00072 19.0 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KKK16324.1 - 0.00055 19.3 0.0 0.0012 18.2 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 KKK16324.1 - 0.0018 18.8 0.1 1.8 9.2 0.0 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KKK16324.1 - 0.0024 17.9 0.0 0.0061 16.5 0.0 1.7 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 KKK16324.1 - 0.0084 15.4 0.4 0.013 14.8 0.4 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KKK16324.1 - 0.072 12.1 0.3 0.11 11.5 0.3 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Trp_halogenase PF04820.14 KKK16324.1 - 0.083 11.7 0.0 0.26 10.1 0.1 1.7 2 0 0 2 2 2 0 Tryptophan halogenase GIDA PF01134.22 KKK16324.1 - 0.23 10.5 0.4 0.35 9.9 0.4 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Hexokinase_2 PF03727.16 KKK16332.1 - 2e-57 194.4 0.0 2.8e-57 193.9 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 KKK16332.1 - 1.6e-47 162.0 0.0 2.5e-47 161.3 0.0 1.3 1 0 0 1 1 1 1 Hexokinase Arylsulfotran_2 PF14269.6 KKK16333.1 - 2.3e-48 165.1 0.2 3.4e-48 164.6 0.2 1.1 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 KKK16333.1 - 6e-13 48.5 0.4 3.8e-11 42.5 0.4 2.5 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) GATase_6 PF13522.6 KKK16346.1 - 2.3e-14 53.7 0.0 4.8e-14 52.7 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 KKK16346.1 - 7.7e-12 45.2 0.0 2.6e-11 43.5 0.0 1.9 2 0 0 2 2 2 1 Glutamine amidotransferase domain Pribosyltran PF00156.27 KKK16346.1 - 8e-07 28.7 0.0 1.8e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.6 KKK16346.1 - 5.3e-05 22.3 0.0 0.00011 21.2 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferases class-II PRTase_2 PF15609.6 KKK16346.1 - 0.05 13.1 0.0 0.14 11.7 0.0 1.7 1 1 0 1 1 1 0 Phosphoribosyl transferase DNA_photolyase PF00875.18 KKK16346.1 - 0.096 12.7 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 DNA photolyase Cation_ATPase_N PF00690.26 KKK16347.1 - 6.5e-20 70.6 0.1 1e-19 70.0 0.1 1.3 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus E1-E2_ATPase PF00122.20 KKK16347.1 - 1.6e-08 34.3 5.5 1.9e-08 34.0 0.1 2.1 2 0 0 2 2 2 1 E1-E2 ATPase DctM PF06808.12 KKK16347.1 - 0.00014 20.9 0.4 0.00016 20.7 0.4 1.0 1 0 0 1 1 1 1 Tripartite ATP-independent periplasmic transporter, DctM component Phage_holin_3_5 PF16085.5 KKK16347.1 - 0.021 15.0 0.6 0.031 14.4 0.6 1.2 1 0 0 1 1 1 0 Bacteriophage holin Hol, superfamily III Glyco_hydro_28 PF00295.17 KKK16348.1 - 2.9e-55 187.6 6.2 3.8e-55 187.2 6.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.6 KKK16348.1 - 5.9e-05 23.0 4.0 0.001 18.9 2.5 2.3 1 1 1 2 2 2 2 Right handed beta helix region DUF4097 PF13349.6 KKK16348.1 - 0.00015 21.2 0.0 0.00031 20.2 0.0 1.4 1 1 0 1 1 1 1 Putative adhesin MmgE_PrpD PF03972.14 KKK16349.1 - 7.7e-146 486.1 0.0 9.3e-146 485.8 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family DUF1266 PF06889.11 KKK16349.1 - 0.029 14.4 0.0 0.53 10.3 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1266) Ubiquitin_2 PF14560.6 KKK16349.1 - 0.036 14.5 0.3 0.086 13.3 0.3 1.6 1 0 0 1 1 1 0 Ubiquitin-like domain DNA_methylase PF00145.17 KKK16350.1 - 3.3e-44 151.6 0.0 1.6e-31 109.9 0.0 2.2 1 1 1 2 2 2 2 C-5 cytosine-specific DNA methylase Med9 PF07544.13 KKK16372.1 - 9.4e-16 57.7 0.0 1.5e-15 57.0 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 Med21 PF11221.8 KKK16372.1 - 0.077 13.2 5.1 0.13 12.5 5.0 1.7 1 1 0 1 1 1 0 Subunit 21 of Mediator complex DUF5082 PF16888.5 KKK16372.1 - 0.096 13.0 0.6 0.24 11.7 0.2 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) GP41 PF00517.17 KKK16372.1 - 0.12 12.2 0.1 0.16 11.8 0.1 1.1 1 0 0 1 1 1 0 Retroviral envelope protein XhlA PF10779.9 KKK16372.1 - 0.19 11.9 0.5 0.35 11.1 0.4 1.5 1 1 0 1 1 1 0 Haemolysin XhlA DUF2730 PF10805.8 KKK16372.1 - 0.23 11.6 0.0 0.34 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) iPGM_N PF06415.13 KKK16373.1 - 5.1e-77 258.2 0.0 7e-77 257.7 0.0 1.2 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Metalloenzyme PF01676.18 KKK16373.1 - 5.2e-70 235.6 0.0 6e-70 235.4 0.0 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily Phosphodiest PF01663.22 KKK16373.1 - 8.9e-05 22.2 0.0 0.00015 21.4 0.0 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 KKK16373.1 - 0.0023 17.4 0.0 0.013 14.9 0.0 2.3 2 1 0 2 2 2 1 Sulfatase Alk_phosphatase PF00245.20 KKK16373.1 - 0.076 12.0 0.1 0.29 10.0 0.1 1.8 2 0 0 2 2 2 0 Alkaline phosphatase AP_endonuc_2 PF01261.24 KKK16373.1 - 0.12 11.9 0.0 0.26 10.7 0.0 1.6 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel DUF2235 PF09994.9 KKK16373.1 - 0.14 11.5 0.0 10 5.4 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) Glyco_hydro_92 PF07971.12 KKK16374.1 - 1.5e-17 63.7 0.0 1.8e-17 63.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Prenylcys_lyase PF07156.14 KKK16375.1 - 6.1e-98 328.3 0.0 7.6e-98 327.9 0.0 1.0 1 0 0 1 1 1 1 Prenylcysteine lyase NAD_binding_8 PF13450.6 KKK16375.1 - 1e-12 48.1 0.0 2.6e-12 46.8 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 KKK16375.1 - 1.1e-11 44.7 0.0 2.5e-11 43.6 0.0 1.5 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.24 KKK16375.1 - 1.1e-08 35.0 0.2 7.2e-06 25.8 0.7 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KKK16375.1 - 1.6e-05 24.9 0.2 0.00043 20.3 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 KKK16375.1 - 0.00049 19.4 0.1 0.023 14.0 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KKK16375.1 - 0.006 15.3 0.3 0.97 8.1 0.3 2.1 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox PF00070.27 KKK16375.1 - 0.0083 16.7 0.1 5.2 7.7 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KKK16375.1 - 0.049 12.8 0.0 6 5.9 0.0 2.1 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 KKK16375.1 - 0.069 12.4 0.1 0.12 11.6 0.1 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.6 KKK16375.1 - 0.1 11.9 0.1 3.7 6.7 0.1 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KKK16375.1 - 0.12 11.5 0.7 0.73 8.8 0.4 1.9 2 0 0 2 2 2 0 FAD binding domain FAD_oxidored PF12831.7 KKK16375.1 - 0.25 10.6 0.2 8.1 5.7 0.0 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase SHMT PF00464.19 KKK16376.1 - 4.1e-207 687.5 0.0 4.8e-207 687.3 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.21 KKK16376.1 - 1.2e-05 24.7 0.0 3.4e-05 23.2 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KKK16376.1 - 0.062 11.8 0.0 0.1 11.1 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 KKK16376.1 - 0.12 11.6 0.0 0.2 10.9 0.0 1.6 1 1 0 1 1 1 0 Beta-eliminating lyase DUF3040 PF11239.8 KKK16376.1 - 0.15 12.3 0.1 0.3 11.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) CSN8_PSD8_EIF3K PF10075.9 KKK16377.1 - 7.8e-44 149.2 0.1 1e-43 148.8 0.1 1.1 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family OB_Dis3 PF17849.1 KKK16377.1 - 0.035 14.1 0.0 0.065 13.3 0.0 1.4 1 0 0 1 1 1 0 Dis3-like cold-shock domain 2 (CSD2) PDCD2_C PF04194.13 KKK16378.1 - 4.7e-40 137.5 0.0 1.8e-39 135.6 0.0 2.0 3 0 0 3 3 3 1 Programmed cell death protein 2, C-terminal putative domain Pkinase PF00069.25 KKK16379.1 - 1.6e-72 244.0 0.0 2.1e-72 243.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK16379.1 - 8.8e-30 103.8 0.0 1.1e-29 103.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KKK16379.1 - 1.4e-07 31.1 0.0 2.3e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KKK16379.1 - 8.2e-05 21.5 0.0 0.00014 20.8 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KKK16379.1 - 0.00016 21.1 0.0 0.00029 20.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KKK16379.1 - 0.00053 20.0 0.1 0.00088 19.3 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family BRD4_CDT PF17105.5 KKK16379.1 - 0.21 11.2 1.1 0.45 10.1 1.1 1.5 1 0 0 1 1 1 0 C-terminal domain of bromodomain protein 4 AMMECR1 PF01871.17 KKK16380.1 - 2.7e-40 137.7 0.0 6.3e-40 136.5 0.0 1.5 2 0 0 2 2 2 1 AMMECR1 DUF3767 PF12597.8 KKK16381.1 - 4.4e-35 119.5 0.2 6.9e-35 118.9 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3767) FAM153 PF15722.5 KKK16381.1 - 5.7 7.3 7.3 14 6.0 0.2 3.0 3 0 0 3 3 3 0 FAM153 family DUF1744 PF08490.12 KKK16382.1 - 2.3e-153 510.5 0.0 3.2e-153 510.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.19 KKK16382.1 - 6.1e-85 285.3 2.4 7.6e-85 285.0 0.4 2.2 3 0 0 3 3 3 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.21 KKK16382.1 - 2e-15 56.5 0.0 1.3e-12 47.2 0.0 2.8 2 1 0 2 2 2 2 DNA polymerase family B DNA_pol_B_exo2 PF10108.9 KKK16382.1 - 2.3e-08 34.0 0.1 5.9e-08 32.7 0.1 1.6 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 KKK16382.1 - 5e-05 23.3 0.0 0.0002 21.4 0.0 2.0 1 0 0 1 1 1 1 RNase_H superfamily AAA PF00004.29 KKK16383.1 - 1.3e-41 142.1 0.0 2.6e-41 141.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 KKK16383.1 - 9.3e-30 102.4 0.1 3.3e-29 100.6 0.1 2.0 2 0 0 2 2 1 1 Vps4 C terminal oligomerisation domain MIT PF04212.18 KKK16383.1 - 3.1e-24 84.8 2.5 3.1e-24 84.8 2.5 1.9 2 0 0 2 2 1 1 MIT (microtubule interacting and transport) domain AAA_lid_3 PF17862.1 KKK16383.1 - 9.8e-07 28.5 0.1 4e-05 23.3 0.0 2.8 3 0 0 3 3 2 1 AAA+ lid domain RuvB_N PF05496.12 KKK16383.1 - 6.7e-06 25.9 0.0 1.5e-05 24.8 0.0 1.7 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KKK16383.1 - 7e-06 26.5 0.0 8.4e-05 23.0 0.0 2.5 1 1 0 1 1 1 1 AAA ATPase domain IstB_IS21 PF01695.17 KKK16383.1 - 1.6e-05 24.8 0.0 3.6e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_5 PF07728.14 KKK16383.1 - 2.8e-05 24.1 0.0 0.00013 22.0 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) DUF815 PF05673.13 KKK16383.1 - 4.5e-05 22.7 0.0 0.0006 19.0 0.0 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF815) RNA_helicase PF00910.22 KKK16383.1 - 4.8e-05 23.7 0.0 0.01 16.2 0.0 2.8 2 0 0 2 2 2 1 RNA helicase AAA_22 PF13401.6 KKK16383.1 - 8.1e-05 22.9 0.1 0.013 15.7 0.0 2.5 1 1 1 2 2 2 1 AAA domain TIP49 PF06068.13 KKK16383.1 - 8.3e-05 21.9 0.0 0.00014 21.2 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_18 PF13238.6 KKK16383.1 - 0.00027 21.5 0.1 0.001 19.6 0.0 2.1 2 1 0 2 2 1 1 AAA domain AAA_33 PF13671.6 KKK16383.1 - 0.0008 19.6 0.0 0.0019 18.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.14 KKK16383.1 - 0.0013 18.9 0.0 0.0093 16.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_14 PF13173.6 KKK16383.1 - 0.0026 17.8 0.0 0.0052 16.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 KKK16383.1 - 0.003 17.3 0.0 0.012 15.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain USP8_dimer PF08969.11 KKK16383.1 - 0.0047 17.1 2.6 0.011 15.9 2.6 1.7 1 0 0 1 1 1 1 USP8 dimerisation domain AAA_17 PF13207.6 KKK16383.1 - 0.0061 17.0 0.0 0.021 15.2 0.0 2.0 1 0 0 1 1 1 1 AAA domain Bac_DnaA PF00308.18 KKK16383.1 - 0.014 15.3 0.0 0.064 13.1 0.0 2.0 1 1 0 1 1 1 0 Bacterial dnaA protein AAA_7 PF12775.7 KKK16383.1 - 0.018 14.6 0.1 0.11 12.0 0.0 2.2 2 1 0 2 2 2 0 P-loop containing dynein motor region AAA_25 PF13481.6 KKK16383.1 - 0.025 14.1 0.1 1.5 8.3 0.1 2.6 1 1 1 2 2 2 0 AAA domain Mg_chelatase PF01078.21 KKK16383.1 - 0.027 13.8 0.2 0.093 12.1 0.1 2.0 2 1 0 2 2 2 0 Magnesium chelatase, subunit ChlI ATPase_2 PF01637.18 KKK16383.1 - 0.038 13.9 0.6 0.71 9.7 0.0 2.5 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea CPT PF07931.12 KKK16383.1 - 0.062 13.1 0.0 0.29 11.0 0.0 1.9 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein NACHT PF05729.12 KKK16383.1 - 0.08 12.8 0.0 0.6 10.0 0.0 2.1 1 1 1 2 2 2 0 NACHT domain Cytidylate_kin PF02224.18 KKK16383.1 - 0.1 12.4 0.9 0.31 10.7 0.0 2.3 2 1 1 3 3 3 0 Cytidylate kinase Parvo_NS1 PF01057.17 KKK16383.1 - 0.12 11.5 0.0 0.26 10.4 0.0 1.5 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Guanylate_kin PF00625.21 KKK16383.1 - 0.13 12.0 0.0 0.39 10.4 0.0 1.8 1 0 0 1 1 1 0 Guanylate kinase Prefoldin_2 PF01920.20 KKK16384.1 - 1.2e-17 63.8 15.1 1.2e-17 63.8 12.0 2.0 2 0 0 2 2 2 1 Prefoldin subunit ERp29 PF07749.12 KKK16384.1 - 0.062 14.2 3.0 0.13 13.2 3.0 1.6 1 1 0 1 1 1 0 Endoplasmic reticulum protein ERp29, C-terminal domain PHM7_cyt PF14703.6 KKK16384.1 - 0.23 11.7 5.7 0.83 9.9 5.7 1.9 1 1 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter DUF724 PF05266.14 KKK16384.1 - 0.32 10.8 9.7 1.5 8.6 2.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF724) DivIC PF04977.15 KKK16384.1 - 0.49 10.2 15.7 0.14 12.0 1.1 3.1 3 0 0 3 3 3 0 Septum formation initiator Spc7 PF08317.11 KKK16384.1 - 0.92 8.3 13.1 1.3 7.9 11.4 1.9 1 1 1 2 2 2 0 Spc7 kinetochore protein FlaC_arch PF05377.11 KKK16384.1 - 1.1 9.7 7.3 14 6.1 0.2 2.9 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) HrpB7 PF09486.10 KKK16384.1 - 1.5 9.2 9.7 0.72 10.2 2.5 2.5 3 0 0 3 3 3 0 Bacterial type III secretion protein (HrpB7) BRE1 PF08647.11 KKK16384.1 - 1.6 8.9 12.0 2 8.6 2.4 2.9 3 0 0 3 3 3 0 BRE1 E3 ubiquitin ligase Spc24 PF08286.11 KKK16384.1 - 1.7 9.0 13.8 2.2 8.6 1.7 2.8 2 1 1 3 3 3 0 Spc24 subunit of Ndc80 Prefoldin PF02996.17 KKK16384.1 - 2.1 8.3 11.6 6.1 6.8 8.9 2.7 2 1 0 2 2 2 0 Prefoldin subunit TolA_bind_tri PF16331.5 KKK16384.1 - 3.4 7.8 17.5 0.14 12.3 1.0 3.5 3 1 0 3 3 3 0 TolA binding protein trimerisation UPF0242 PF06785.11 KKK16384.1 - 3.8 7.6 14.3 3.4 7.7 12.4 1.9 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Csm1_N PF18504.1 KKK16384.1 - 9.5 6.7 13.6 3.7 7.9 0.9 3.2 3 1 0 3 3 3 0 Csm1 N-terminal domain SGT1 PF07093.11 KKK16385.1 - 5.7e-89 299.1 9.6 1.9e-84 284.2 0.0 2.1 1 1 1 2 2 2 2 SGT1 protein Cnn_1N PF07989.11 KKK16386.1 - 1.1e-24 86.4 5.6 1.1e-24 86.4 5.6 14.7 5 3 10 15 15 15 2 Centrosomin N-terminal motif 1 PACT_coil_coil PF10495.9 KKK16386.1 - 1.4e-21 76.8 1.6 1.4e-21 76.8 1.6 4.2 4 0 0 4 4 4 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein Bacillus_HBL PF05791.11 KKK16386.1 - 5.9e-05 23.0 7.0 5.9e-05 23.0 7.0 7.0 3 2 2 7 7 7 1 Bacillus haemolytic enterotoxin (HBL) TMF_DNA_bd PF12329.8 KKK16386.1 - 0.0043 17.0 13.5 0.0043 17.0 13.5 14.0 8 4 3 14 14 14 3 TATA element modulatory factor 1 DNA binding Fez1 PF06818.15 KKK16386.1 - 0.0096 16.4 32.8 0.0096 16.4 32.8 7.9 1 1 6 8 8 8 1 Fez1 Pox_A_type_inc PF04508.12 KKK16386.1 - 0.059 13.2 0.1 0.059 13.2 0.1 10.5 13 0 0 13 13 13 0 Viral A-type inclusion protein repeat Nop PF01798.18 KKK16387.1 - 3.8e-85 285.0 0.1 3.8e-85 285.0 0.1 1.7 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 KKK16387.1 - 2.7e-19 69.3 0.1 1.5e-18 66.9 0.1 2.4 1 0 0 1 1 1 1 NOP5NT (NUC127) domain CobT PF06213.12 KKK16387.1 - 0.54 9.6 18.5 1.6 8.1 18.5 1.8 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT YL1 PF05764.13 KKK16387.1 - 1.2 9.2 26.7 1.9 8.6 26.7 1.3 1 0 0 1 1 1 0 YL1 nuclear protein RNA_polI_A34 PF08208.11 KKK16387.1 - 1.3 9.0 37.1 2.7 8.0 37.1 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 DUF1682 PF07946.14 KKK16387.1 - 3.7 6.7 23.1 20 4.2 0.0 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1682) Cpn60_TCP1 PF00118.24 KKK16389.1 - 3.7e-166 553.6 0.2 4.2e-166 553.4 0.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family MOZ_SAS PF01853.18 KKK16390.1 - 3.8e-63 212.4 0.0 6.5e-63 211.6 0.0 1.4 1 1 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 KKK16390.1 - 8.3e-18 63.7 0.5 1.5e-17 62.9 0.5 1.5 1 0 0 1 1 1 1 MYST family zinc finger domain Inhibitor_I10 PF12559.8 KKK16390.1 - 0.0025 18.0 0.0 0.0055 16.9 0.0 1.5 1 0 0 1 1 1 1 Serine endopeptidase inhibitors RRM_1 PF00076.22 KKK16391.1 - 1e-11 44.5 0.0 1.7e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) tRNA-synt_2 PF00152.20 KKK16392.1 - 1.9e-70 237.4 0.0 3.3e-70 236.7 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KKK16392.1 - 6.2e-06 26.1 0.0 1.1e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain ILVD_EDD PF00920.21 KKK16394.1 - 1.1e-210 700.7 0.5 1.5e-210 700.3 0.5 1.2 1 0 0 1 1 1 1 Dehydratase family Abhydrolase_1 PF00561.20 KKK16395.1 - 9.3e-19 68.1 0.0 1e-17 64.6 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KKK16395.1 - 1.6e-07 32.1 0.1 3.6e-07 31.0 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KKK16395.1 - 2.5e-07 30.2 0.0 7.6e-05 22.1 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 DUF3246 PF11596.8 KKK16395.1 - 0.00046 19.7 5.2 0.00069 19.1 5.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3246) Ndr PF03096.14 KKK16395.1 - 0.00097 17.9 0.0 0.0014 17.4 0.0 1.1 1 0 0 1 1 1 1 Ndr family Abhydrolase_4 PF08386.10 KKK16395.1 - 0.0049 17.0 0.0 0.011 15.8 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein DUF913 PF06025.12 KKK16395.1 - 0.034 13.1 0.2 0.045 12.7 0.2 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) THOC2_N PF16134.5 KKK16395.1 - 0.09 11.4 3.7 0.12 10.9 3.7 1.1 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus KCT2 PF17818.1 KKK16395.1 - 1.3 9.1 4.7 2.2 8.4 4.7 1.3 1 0 0 1 1 1 0 Keratinocyte-associated gene product DUF4611 PF15387.6 KKK16395.1 - 2.2 8.6 7.3 6.7 7.0 6.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) SR-25 PF10500.9 KKK16395.1 - 2.7 7.5 16.7 0.041 13.5 9.8 1.4 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein TFIIE-A_C PF11521.8 KKK16395.1 - 6.2 7.2 6.4 18 5.7 6.4 1.8 1 0 0 1 1 1 0 C-terminal general transcription factor TFIIE alpha DUF1899 PF08953.11 KKK16396.1 - 1.7e-34 117.5 0.0 4e-34 116.3 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40_4 PF16300.5 KKK16396.1 - 9.3e-20 70.3 0.1 1.7e-19 69.4 0.1 1.5 1 0 0 1 1 1 1 Type of WD40 repeat WD40 PF00400.32 KKK16396.1 - 6.6e-18 64.7 5.5 0.00033 21.4 0.1 5.3 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKK16396.1 - 1.5e-05 25.2 0.0 0.17 12.2 0.1 3.6 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KKK16396.1 - 0.005 15.6 0.2 0.37 9.4 0.2 2.1 1 1 1 2 2 2 2 Nucleoporin Nup120/160 DivIC PF04977.15 KKK16396.1 - 0.8 9.5 2.1 1.6 8.6 2.1 1.4 1 0 0 1 1 1 0 Septum formation initiator SlyX PF04102.12 KKK16396.1 - 1.2 9.8 2.8 0.7 10.6 0.6 1.7 2 0 0 2 2 2 0 SlyX Kinesin PF00225.23 KKK16397.1 - 2.6e-105 352.0 0.3 2.6e-105 352.0 0.3 2.2 2 1 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KKK16397.1 - 5.5e-60 201.6 0.0 1.6e-59 200.2 0.0 1.8 1 0 0 1 1 1 1 Microtubule binding WEMBL PF05701.11 KKK16397.1 - 0.00037 19.3 12.4 0.00037 19.3 12.4 2.6 2 1 1 3 3 3 1 Weak chloroplast movement under blue light AAA_16 PF13191.6 KKK16397.1 - 0.0059 17.0 0.0 0.0059 17.0 0.0 2.4 2 1 0 2 2 2 1 AAA ATPase domain AAA_24 PF13479.6 KKK16397.1 - 0.055 13.2 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KKK16397.1 - 0.078 13.2 0.0 0.078 13.2 0.0 2.8 2 1 1 3 3 3 0 AAA domain MFS_1 PF07690.16 KKK16399.1 - 4.9e-17 61.9 55.5 1.4e-15 57.1 29.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KKK16399.1 - 0.007 14.7 0.1 0.007 14.7 0.1 2.0 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family RAI16-like PF10257.9 KKK16400.1 - 6.9e-86 288.3 0.0 9.9e-86 287.8 0.0 1.2 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein CBFD_NFYB_HMF PF00808.23 KKK16401.1 - 1.1e-15 57.7 2.3 1.8e-15 57.0 2.3 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KKK16401.1 - 2.7e-05 24.6 0.8 2.7e-05 24.6 0.8 1.6 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 DUF1115 PF06544.12 KKK16404.1 - 1.1e-10 41.8 0.0 1.7e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) Pribosyltran_N PF13793.6 KKK16405.1 - 7.8e-45 151.6 0.1 8.4e-42 141.8 0.0 2.4 2 0 0 2 2 2 2 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 KKK16405.1 - 1.2e-35 123.2 0.1 8.4e-31 107.4 0.1 2.2 2 0 0 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 KKK16405.1 - 1.5e-09 37.5 0.0 1.4e-06 27.9 0.1 2.4 2 0 0 2 2 2 2 Phosphoribosyl transferase domain Ldh_1_C PF02866.18 KKK16407.1 - 2.4e-46 157.7 0.0 6.9e-46 156.2 0.0 1.8 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 KKK16407.1 - 2.1e-44 151.0 0.0 2e-43 147.8 0.0 2.0 2 0 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 KKK16407.1 - 0.00072 18.6 0.0 0.001 18.2 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family THF_DHG_CYH_C PF02882.19 KKK16407.1 - 0.053 12.8 0.0 0.51 9.7 0.0 2.5 2 1 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Semialdhyde_dh PF01118.24 KKK16407.1 - 0.066 13.6 0.2 0.77 10.2 0.0 2.6 2 1 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain AAA PF00004.29 KKK16408.1 - 1.8e-17 64.0 0.0 3.3e-17 63.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KKK16408.1 - 2.5e-06 27.8 0.2 0.00023 21.5 0.0 3.2 1 1 2 3 3 3 1 AAA domain AAA_16 PF13191.6 KKK16408.1 - 0.00019 21.8 0.1 0.00065 20.1 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 KKK16408.1 - 0.0067 16.4 0.0 0.013 15.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_11 PF13086.6 KKK16408.1 - 0.021 14.6 0.0 0.048 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 KKK16408.1 - 0.025 14.5 0.0 0.06 13.3 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_19 PF13245.6 KKK16408.1 - 0.029 14.7 0.1 0.067 13.5 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KKK16408.1 - 0.055 13.2 0.0 0.12 12.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KKK16408.1 - 0.056 13.2 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF5353 PF17304.2 KKK16409.1 - 6.5e-26 89.9 4.3 1.1e-25 89.1 4.3 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5353) V-SNARE_C PF12352.8 KKK16409.1 - 6.5e-16 58.4 0.6 1.5e-15 57.2 0.4 1.8 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 KKK16409.1 - 0.00025 20.9 0.0 0.0018 18.2 0.0 2.3 2 0 0 2 2 2 1 Sec20 BAR_2 PF10455.9 KKK16409.1 - 0.011 14.9 0.0 0.011 14.9 0.0 1.6 2 0 0 2 2 2 0 Bin/amphiphysin/Rvs domain for vesicular trafficking Sigma70_r4 PF04545.16 KKK16409.1 - 0.032 13.7 0.3 0.072 12.6 0.3 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 She9_MDM33 PF05546.11 KKK16409.1 - 0.057 13.2 0.3 0.057 13.2 0.3 1.9 2 0 0 2 2 2 0 She9 / Mdm33 family Goodbye PF17109.5 KKK16409.1 - 0.08 13.4 4.9 0.25 11.8 1.0 3.1 3 0 0 3 3 3 0 fungal STAND N-terminal Goodbye domain TPR_MLP1_2 PF07926.12 KKK16409.1 - 1.1 9.4 12.4 0.45 10.6 2.3 3.1 3 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein PP28 PF10252.9 KKK16409.1 - 8.6 6.9 13.0 0.24 11.9 2.8 2.8 2 1 0 2 2 2 0 Casein kinase substrate phosphoprotein PP28 2-oxoacid_dh PF00198.23 KKK16410.1 - 4.5e-77 258.6 0.1 5.9e-77 258.2 0.1 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 KKK16410.1 - 5.7e-17 61.3 2.5 1.2e-16 60.3 0.4 2.4 2 0 0 2 2 2 1 Biotin-requiring enzyme E3_binding PF02817.17 KKK16410.1 - 6.2e-13 48.8 0.6 1.9e-12 47.3 0.6 1.9 1 0 0 1 1 1 1 e3 binding domain SopE_GEF PF07487.13 KKK16410.1 - 0.057 13.5 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 SopE GEF domain Sec7 PF01369.20 KKK16411.1 - 5.7e-71 238.0 1.2 1.6e-70 236.5 1.2 1.8 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 KKK16411.1 - 2e-43 148.0 12.8 4.4e-43 146.9 8.2 3.0 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 KKK16411.1 - 7e-35 118.7 10.0 1e-32 111.8 0.1 5.6 5 0 0 5 5 5 2 Domain of unknown function (DUF1981) DCB PF16213.5 KKK16411.1 - 2.5e-16 59.9 9.7 2.9e-16 59.6 0.4 3.8 4 0 0 4 4 4 1 Dimerisation and cyclophilin-binding domain of Mon2 DUF4168 PF13767.6 KKK16411.1 - 0.55 11.4 3.4 31 5.8 0.0 4.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4168) Sirohm_synth_C PF14823.6 KKK16412.1 - 6.6e-33 112.2 0.0 1e-32 111.6 0.0 1.3 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal NAD_binding_7 PF13241.6 KKK16412.1 - 2e-31 108.5 0.0 3.1e-31 107.9 0.0 1.3 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_M PF14824.6 KKK16412.1 - 9.9e-15 53.7 0.1 9.9e-15 53.7 0.1 1.6 2 0 0 2 2 2 1 Sirohaem biosynthesis protein central Pyr_redox_3 PF13738.6 KKK16412.1 - 0.016 14.5 0.1 0.023 13.9 0.1 1.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 KKK16412.1 - 0.02 15.1 0.1 0.045 14.0 0.1 1.6 1 1 0 1 1 1 0 TrkA-N domain LSDAT_prok PF18171.1 KKK16412.1 - 0.056 12.7 0.1 0.083 12.1 0.1 1.2 1 0 0 1 1 1 0 SLOG in TRPM, prokaryote Shikimate_DH PF01488.20 KKK16412.1 - 0.079 13.0 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF4061 PF13270.6 KKK16412.1 - 0.12 12.7 0.0 0.22 11.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4061) APH PF01636.23 KKK16417.1 - 1.3e-11 44.9 0.1 2.5e-10 40.7 0.1 2.2 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 KKK16417.1 - 0.13 11.6 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase FAM83 PF07894.12 KKK16417.1 - 0.15 11.6 0.1 0.32 10.5 0.1 1.5 1 0 0 1 1 1 0 FAM83 A-H DUF1947 PF09183.10 KKK16417.1 - 0.33 11.3 1.8 3.2 8.1 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1947) GLEYA PF10528.9 KKK16418.1 - 0.00022 21.6 0.9 0.00022 21.6 0.9 2.2 2 0 0 2 2 2 1 GLEYA domain Nse4-Nse3_bdg PF15412.6 KKK16420.1 - 0.047 13.8 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 Binding domain of Nse4/EID3 to Nse3-MAGE Sugar_tr PF00083.24 KKK16421.1 - 6.3e-126 420.9 17.6 7.2e-126 420.7 17.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKK16421.1 - 1.7e-21 76.6 23.3 1.7e-21 76.6 23.3 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.16 KKK16423.1 - 1.5e-10 41.0 6.7 1.5e-10 41.0 6.7 3.5 4 0 0 4 4 4 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 KKK16423.1 - 1.7e-10 40.4 36.7 1.7e-10 40.4 36.7 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily SPC12 PF06645.13 KKK16423.1 - 5.9 7.1 9.1 1.2 9.3 1.1 3.7 3 0 0 3 3 3 0 Microsomal signal peptidase 12 kDa subunit (SPC12) Amidohydro_1 PF01979.20 KKK16424.1 - 6.6e-17 61.8 0.0 1.6e-16 60.6 0.0 1.5 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KKK16424.1 - 6.6e-13 48.9 0.2 5.4e-09 36.0 0.1 2.3 2 0 0 2 2 2 2 Amidohydrolase family MFS_1 PF07690.16 KKK16425.1 - 1.9e-30 106.0 33.1 2e-27 96.1 20.8 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KKK16425.1 - 3.1e-11 42.8 2.7 3.1e-11 42.8 2.7 1.7 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1_like PF12832.7 KKK16425.1 - 0.00014 20.9 1.3 0.00014 20.9 1.3 2.3 2 1 0 2 2 2 1 MFS_1 like family MFS_3 PF05977.13 KKK16425.1 - 0.46 8.8 9.1 0.11 10.8 3.1 2.4 2 1 0 2 2 2 0 Transmembrane secretion effector Fungal_TACC PF12709.7 KKK16426.1 - 6.2e-12 45.8 24.3 6.8e-10 39.2 4.3 4.2 4 0 0 4 4 4 2 Fungal Transforming acidic coiled-coil (TACC) proteins FPP PF05911.11 KKK16426.1 - 0.11 10.6 32.2 0.031 12.5 9.3 2.2 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil ERM PF00769.19 KKK16426.1 - 1.4 8.7 52.2 0.31 10.8 18.6 4.0 2 1 2 4 4 4 0 Ezrin/radixin/moesin family DUF4407 PF14362.6 KKK16426.1 - 2 7.7 29.6 9.5 5.5 1.2 3.3 1 1 2 3 3 3 0 Domain of unknown function (DUF4407) DUF3235 PF11574.8 KKK16426.1 - 3.3 8.6 6.8 1.4 9.8 0.1 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3235) CENP-F_leu_zip PF10473.9 KKK16426.1 - 6.6 6.8 44.8 6.9 6.7 10.9 4.2 1 1 3 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Fungal_trans PF04082.18 KKK16428.1 - 8.3e-31 107.0 2.0 1.3e-30 106.4 2.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK16428.1 - 0.0018 18.4 18.5 0.0036 17.4 18.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_jaz PF12171.8 KKK16429.1 - 0.0045 17.2 8.1 0.16 12.3 0.4 3.5 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding Senescence PF06911.12 KKK16429.1 - 0.19 12.0 0.0 0.34 11.2 0.0 1.3 1 0 0 1 1 1 0 Senescence-associated protein zf-met PF12874.7 KKK16429.1 - 5.3 7.6 7.6 0.33 11.4 0.2 3.0 3 0 0 3 3 3 0 Zinc-finger of C2H2 type DUF3446 PF11928.8 KKK16430.1 - 0.01 16.2 6.0 0.012 15.9 6.0 1.1 1 0 0 1 1 1 1 Early growth response N-terminal domain SR-25 PF10500.9 KKK16430.1 - 6.3 6.3 12.8 7.7 6.0 12.8 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DbpA PF03880.15 KKK16431.1 - 0.018 15.0 0.0 0.037 14.0 0.0 1.5 1 0 0 1 1 1 0 DbpA RNA binding domain Peptidase_S10 PF00450.22 KKK16433.1 - 1.7e-110 370.3 0.2 2e-110 370.1 0.2 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Sec66 PF09802.9 KKK16434.1 - 1.3e-82 275.7 1.9 1.6e-82 275.5 1.9 1.1 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 DUF874 PF05917.11 KKK16434.1 - 0.016 14.3 3.0 0.021 13.9 3.0 1.1 1 0 0 1 1 1 0 Helicobacter pylori protein of unknown function (DUF874) DUF3848 PF12959.7 KKK16434.1 - 0.019 15.0 0.0 0.042 13.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3848) Sec2p PF06428.11 KKK16434.1 - 0.043 13.8 2.3 0.11 12.5 2.3 1.7 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p Rib_recp_KP_reg PF05104.12 KKK16434.1 - 0.069 14.2 19.2 0.037 15.1 15.5 2.0 2 0 0 2 2 2 0 Ribosome receptor lysine/proline rich region MCPVI PF02993.14 KKK16434.1 - 2.1 8.1 7.2 0.55 10.0 3.5 1.7 1 1 1 2 2 2 0 Minor capsid protein VI AAA PF00004.29 KKK16435.1 - 1.1e-47 161.8 0.0 2.2e-42 144.6 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KKK16435.1 - 5.8e-10 38.8 0.0 2.1e-09 37.0 0.0 1.9 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 KKK16435.1 - 4.2e-07 30.5 0.2 4e-05 24.1 0.0 3.5 2 1 0 2 2 2 1 AAA ATPase domain IstB_IS21 PF01695.17 KKK16435.1 - 5.4e-07 29.5 0.0 3.3e-06 27.0 0.0 2.1 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_2 PF07724.14 KKK16435.1 - 5.4e-06 26.6 0.0 1.3e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 KKK16435.1 - 0.00026 21.0 0.1 0.0013 18.8 0.0 2.2 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KKK16435.1 - 0.00075 19.8 0.6 0.023 14.9 0.1 3.4 3 1 0 3 3 2 1 AAA domain Bromodomain PF00439.25 KKK16435.1 - 0.0015 18.5 0.0 0.0041 17.1 0.0 1.7 1 0 0 1 1 1 1 Bromodomain RNA_helicase PF00910.22 KKK16435.1 - 0.0044 17.4 0.0 0.011 16.1 0.0 1.7 1 0 0 1 1 1 1 RNA helicase AAA_30 PF13604.6 KKK16435.1 - 0.0087 15.8 0.0 0.019 14.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain Sigma54_activ_2 PF14532.6 KKK16435.1 - 0.0088 16.2 0.0 0.95 9.6 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_25 PF13481.6 KKK16435.1 - 0.012 15.2 0.0 0.045 13.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 KKK16435.1 - 0.013 15.6 0.0 0.037 14.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KKK16435.1 - 0.017 15.3 0.0 0.046 13.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KKK16435.1 - 0.017 15.7 0.0 0.074 13.6 0.0 2.2 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.13 KKK16435.1 - 0.019 14.2 0.0 0.033 13.4 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain RuvB_N PF05496.12 KKK16435.1 - 0.031 14.0 0.0 0.078 12.7 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 KKK16435.1 - 0.044 13.2 0.0 0.11 11.8 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI TsaE PF02367.17 KKK16435.1 - 0.045 13.7 0.0 1.8 8.6 0.0 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 KKK16435.1 - 0.052 14.1 0.0 0.2 12.1 0.0 2.0 2 0 0 2 2 1 0 ABC transporter Sigma54_activat PF00158.26 KKK16435.1 - 0.064 13.0 0.0 1.4 8.6 0.0 2.7 2 1 0 2 2 2 0 Sigma-54 interaction domain AAA_28 PF13521.6 KKK16435.1 - 0.084 13.1 0.0 0.19 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KKK16435.1 - 0.11 12.5 0.0 0.34 10.8 0.0 1.9 2 0 0 2 2 2 0 NACHT domain Parvo_NS1 PF01057.17 KKK16435.1 - 0.11 11.6 0.0 0.22 10.5 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DUF2075 PF09848.9 KKK16435.1 - 0.13 11.5 0.0 0.24 10.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_7 PF12775.7 KKK16435.1 - 0.14 11.7 0.0 0.27 10.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_3 PF07726.11 KKK16435.1 - 0.15 11.9 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Torsin PF06309.11 KKK16435.1 - 0.21 11.7 0.0 0.62 10.2 0.0 1.7 1 0 0 1 1 1 0 Torsin AAA_11 PF13086.6 KKK16435.1 - 0.36 10.6 0.0 0.36 10.6 0.0 3.6 3 1 0 3 3 1 0 AAA domain DUF4187 PF13821.6 KKK16436.1 - 5.8e-23 80.4 3.5 1.7e-22 78.9 3.5 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) G-patch PF01585.23 KKK16436.1 - 2.6e-08 33.6 0.3 1e-05 25.3 0.1 2.5 2 0 0 2 2 2 2 G-patch domain DUF4615 PF15393.6 KKK16436.1 - 0.41 11.2 10.0 0.1 13.2 3.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4615) COesterase PF00135.28 KKK16437.1 - 2.3e-83 280.8 0.1 7.8e-75 252.7 0.0 2.0 2 0 0 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 KKK16437.1 - 3.4e-07 30.3 0.3 1.9e-06 27.9 0.3 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KKK16437.1 - 1.4e-06 28.0 0.1 2.2e-06 27.3 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Nop14 PF04147.12 KKK16438.1 - 7.8e-289 960.8 30.6 9.5e-289 960.5 30.6 1.1 1 0 0 1 1 1 1 Nop14-like family NADH-u_ox-rdase PF10785.9 KKK16438.1 - 0.13 13.0 0.0 0.26 12.0 0.0 1.5 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit HEAT_2 PF13646.6 KKK16439.1 - 0.0025 18.1 0.1 0.0062 16.9 0.1 1.7 1 0 0 1 1 1 1 HEAT repeats Myc_N PF01056.18 KKK16439.1 - 0.033 14.1 0.0 0.042 13.8 0.0 1.2 1 0 0 1 1 1 0 Myc amino-terminal region HEAT PF02985.22 KKK16439.1 - 0.1 12.9 0.0 3 8.3 0.0 2.8 2 0 0 2 2 2 0 HEAT repeat Peptidase_S49_N PF08496.10 KKK16440.1 - 6.2 6.9 8.8 5.6 7.0 4.6 2.1 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Spt20 PF12090.8 KKK16441.1 - 4.9 6.7 27.6 8.5 5.9 27.6 1.3 1 0 0 1 1 1 0 Spt20 family ORC3_N PF07034.11 KKK16442.1 - 1.2e-36 126.5 0.0 1.7e-34 119.5 0.0 2.2 1 1 0 1 1 1 1 Origin recognition complex (ORC) subunit 3 N-terminus ORC_WH_C PF18137.1 KKK16442.1 - 2e-25 89.5 0.7 7.1e-16 58.5 0.1 2.4 1 1 1 2 2 2 2 Origin recognition complex winged helix C-terminal PPR_2 PF13041.6 KKK16443.1 - 9.6e-07 28.9 1.0 1.8 8.8 0.0 5.5 7 0 0 7 7 7 2 PPR repeat family AAA_lid_7 PF17867.1 KKK16443.1 - 0.048 13.9 1.1 3.3 8.0 0.0 3.4 3 0 0 3 3 3 0 Midasin AAA lid domain PPR PF01535.20 KKK16443.1 - 0.074 13.3 2.0 11 6.5 0.0 4.3 5 0 0 5 5 5 0 PPR repeat RhoGAP PF00620.27 KKK16443.1 - 0.19 11.5 0.7 9.7 6.0 0.2 2.5 2 0 0 2 2 2 0 RhoGAP domain CLZ PF16526.5 KKK16443.1 - 9 6.7 7.9 12 6.3 0.9 3.6 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF4407 PF14362.6 KKK16444.1 - 0.79 9.0 52.5 0.28 10.5 20.8 3.1 1 1 2 3 3 3 0 Domain of unknown function (DUF4407) SF-assemblin PF06705.11 KKK16444.1 - 0.89 8.8 46.6 2.5 7.4 17.7 2.7 1 1 1 2 2 2 0 SF-assemblin/beta giardin zf-C2H2 PF00096.26 KKK16445.1 - 1.3e-05 25.4 23.0 0.097 13.2 0.3 4.6 4 0 0 4 4 4 4 Zinc finger, C2H2 type FOXP-CC PF16159.5 KKK16445.1 - 0.0055 17.3 1.1 0.0055 17.3 1.1 3.1 2 1 1 3 3 3 1 FOXP coiled-coil domain DUF629 PF04780.12 KKK16445.1 - 0.48 8.9 5.1 0.99 7.8 5.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF629) FBPase PF00316.20 KKK16455.1 - 2e-69 232.9 0.2 2.6e-69 232.5 0.2 1.1 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain Aha1_N PF09229.11 KKK16456.1 - 2.3e-42 144.4 0.6 4.3e-42 143.6 0.6 1.5 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.11 KKK16456.1 - 2e-20 73.3 0.3 3.7e-20 72.4 0.3 1.5 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein Sacchrp_dh_C PF16653.5 KKK16457.1 - 2.1e-93 313.3 0.0 3.7e-93 312.5 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain Prenyltransf PF01255.19 KKK16457.1 - 8.5e-78 260.9 0.0 2.1e-77 259.7 0.0 1.6 1 1 0 1 1 1 1 Putative undecaprenyl diphosphate synthase Sacchrp_dh_NADP PF03435.18 KKK16457.1 - 3.7e-25 88.7 1.5 2.7e-24 85.9 0.8 2.5 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 KKK16457.1 - 1.8e-08 34.5 0.4 3.5e-08 33.6 0.4 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.6 KKK16457.1 - 0.00013 21.9 1.0 0.00054 19.9 0.1 2.4 3 0 0 3 3 3 1 NAD(P)H-binding NmrA PF05368.13 KKK16457.1 - 0.0032 17.0 0.3 0.0053 16.3 0.3 1.3 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.25 KKK16457.1 - 0.015 14.8 0.6 0.069 12.6 0.1 2.1 2 0 0 2 2 2 0 short chain dehydrogenase 3Beta_HSD PF01073.19 KKK16457.1 - 0.018 14.0 0.5 0.033 13.2 0.0 1.6 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family AlaDh_PNT_C PF01262.21 KKK16457.1 - 0.044 13.1 0.4 0.077 12.3 0.4 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.6 KKK16457.1 - 0.075 13.5 0.2 0.33 11.4 0.3 2.0 2 0 0 2 2 2 0 Putative NAD(P)-binding Acyltransferase PF01553.21 KKK16458.1 - 1e-09 38.1 0.0 0.00051 19.7 0.0 2.3 2 0 0 2 2 2 2 Acyltransferase Vps36_ESCRT-II PF11605.8 KKK16459.1 - 0.00015 21.9 0.0 0.00038 20.6 0.0 1.6 2 0 0 2 2 2 1 Vacuolar protein sorting protein 36 Vps36 PH_TFIIH PF08567.11 KKK16459.1 - 0.0022 18.3 0.1 0.025 14.9 0.1 2.3 1 1 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain UCR_hinge PF02320.16 KKK16460.1 - 9.9e-27 92.9 9.2 9.9e-27 92.9 9.2 2.1 2 1 0 2 2 1 1 Ubiquinol-cytochrome C reductase hinge protein ORC6 PF05460.13 KKK16460.1 - 0.0091 15.3 5.7 0.0096 15.2 5.7 1.0 1 0 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) Mpp10 PF04006.12 KKK16460.1 - 0.013 14.0 22.2 0.016 13.7 22.2 1.1 1 0 0 1 1 1 0 Mpp10 protein DUF4211 PF13926.6 KKK16460.1 - 0.027 14.5 3.2 0.027 14.5 3.2 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4211) RR_TM4-6 PF06459.12 KKK16460.1 - 0.055 13.3 16.6 0.067 13.0 16.6 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 BUD22 PF09073.10 KKK16460.1 - 0.063 12.6 21.2 0.073 12.4 21.2 1.0 1 0 0 1 1 1 0 BUD22 Hamartin PF04388.12 KKK16460.1 - 0.12 11.0 10.0 0.14 10.8 10.0 1.0 1 0 0 1 1 1 0 Hamartin protein DDHD PF02862.17 KKK16460.1 - 0.13 12.4 4.6 0.14 12.3 4.6 1.1 1 0 0 1 1 1 0 DDHD domain SAPS PF04499.15 KKK16460.1 - 0.25 10.1 9.8 0.26 10.0 9.8 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF913 PF06025.12 KKK16460.1 - 0.25 10.3 9.6 0.31 10.0 9.6 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Pox_Ag35 PF03286.14 KKK16460.1 - 0.38 10.5 19.1 0.5 10.1 19.1 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein CobT PF06213.12 KKK16460.1 - 0.51 9.7 23.2 0.64 9.4 23.2 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Ndc1_Nup PF09531.10 KKK16460.1 - 0.59 8.8 1.7 0.65 8.6 1.7 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF1631 PF07793.11 KKK16460.1 - 0.64 8.4 10.2 0.72 8.2 10.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) Raftlin PF15250.6 KKK16460.1 - 0.77 8.4 11.9 0.86 8.3 11.9 1.1 1 0 0 1 1 1 0 Raftlin RRN3 PF05327.11 KKK16460.1 - 0.96 7.9 11.5 1.1 7.7 11.5 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF4045 PF13254.6 KKK16460.1 - 1.2 8.7 19.8 1.4 8.4 19.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) DUF4471 PF14740.6 KKK16460.1 - 1.3 8.2 6.3 1.8 7.7 6.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4471) Zip PF02535.22 KKK16460.1 - 1.7 7.8 9.9 1.7 7.8 9.9 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter MDM31_MDM32 PF08118.11 KKK16460.1 - 1.8 7.1 5.9 2.2 6.8 5.9 1.1 1 0 0 1 1 1 0 Yeast mitochondrial distribution and morphology (MDM) proteins Spore_coat_CotO PF14153.6 KKK16460.1 - 2 8.3 25.8 3.1 7.7 25.8 1.3 1 0 0 1 1 1 0 Spore coat protein CotO DUF5427 PF10310.9 KKK16460.1 - 2.6 6.9 17.7 2.9 6.8 17.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) Nop14 PF04147.12 KKK16460.1 - 2.7 6.1 24.9 3.1 5.9 24.9 1.0 1 0 0 1 1 1 0 Nop14-like family NPR3 PF03666.13 KKK16460.1 - 2.9 6.6 11.6 3.3 6.4 11.6 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 SpoIIP PF07454.11 KKK16460.1 - 3.4 7.1 13.3 4.5 6.7 13.3 1.3 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Tim54 PF11711.8 KKK16460.1 - 3.5 6.3 19.1 4.1 6.1 19.1 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 SLC12 PF03522.15 KKK16460.1 - 3.9 6.4 9.3 4.5 6.2 9.3 1.1 1 0 0 1 1 1 0 Solute carrier family 12 GET2 PF08690.10 KKK16460.1 - 5.1 6.7 8.7 6.1 6.4 8.7 1.2 1 0 0 1 1 1 0 GET complex subunit GET2 LAP1C PF05609.12 KKK16460.1 - 5.3 6.0 17.1 6.1 5.8 17.1 1.0 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Neur_chan_memb PF02932.16 KKK16460.1 - 6.2 6.8 8.7 7.5 6.5 8.7 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Trypan_PARP PF05887.11 KKK16460.1 - 6.7 6.7 25.7 10 6.1 25.7 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) COG4 PF08318.12 KKK16460.1 - 6.9 5.7 10.3 12 4.8 10.3 1.5 1 1 0 1 1 1 0 COG4 transport protein PPL5 PF18168.1 KKK16460.1 - 9.1 5.5 9.7 10 5.3 9.7 1.2 1 0 0 1 1 1 0 Prim-pol family 5 MFS_1 PF07690.16 KKK16461.1 - 4.4e-12 45.6 22.4 2.6e-11 43.0 19.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KKK16461.1 - 2.2 7.0 10.0 0.071 12.0 2.2 2.0 2 1 0 2 2 2 0 MFS_1 like family Gti1_Pac2 PF09729.9 KKK16464.1 - 1.5e-46 158.8 1.0 7.3e-39 133.7 0.1 2.1 1 1 1 2 2 2 2 Gti1/Pac2 family NucS PF01939.16 KKK16464.1 - 0.15 11.4 0.0 0.21 10.9 0.0 1.1 1 0 0 1 1 1 0 Endonuclease NucS PRP21_like_P PF12230.8 KKK16477.1 - 3.5e-58 197.0 10.2 3.5e-58 197.0 10.2 1.8 2 0 0 2 2 2 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.20 KKK16477.1 - 1.5e-37 127.3 7.4 6.6e-20 70.9 0.1 2.9 3 0 0 3 3 3 2 Surp module zf_UBZ PF18439.1 KKK16477.1 - 0.0078 15.8 0.2 0.018 14.6 0.2 1.7 1 0 0 1 1 1 1 Ubiquitin-Binding Zinc Finger B12D PF06522.11 KKK16478.1 - 0.095 12.5 0.1 0.2 11.5 0.1 1.6 1 1 0 1 1 1 0 NADH-ubiquinone reductase complex 1 MLRQ subunit RHH_5 PF07878.11 KKK16478.1 - 0.15 12.0 0.2 0.29 11.0 0.0 1.5 2 0 0 2 2 2 0 CopG-like RHH_1 or ribbon-helix-helix domain, RHH_5 DUF1616 PF07760.11 KKK16478.1 - 0.16 11.4 0.0 0.2 11.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1616) PMT PF02366.18 KKK16479.1 - 2e-80 269.9 16.5 4.7e-80 268.7 16.5 1.6 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 KKK16479.1 - 8.1e-67 224.7 10.4 8.1e-67 224.7 10.4 2.6 3 0 0 3 3 3 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 KKK16479.1 - 1.3e-46 158.9 0.0 2.1e-46 158.1 0.0 1.3 1 0 0 1 1 1 1 MIR domain SET PF00856.28 KKK16480.1 - 1.8e-13 51.2 0.2 1.8e-13 51.2 0.2 3.7 3 2 0 3 3 3 1 SET domain AWS PF17907.1 KKK16480.1 - 1.1e-07 31.7 5.3 1.1e-07 31.7 5.3 2.1 2 0 0 2 2 2 1 AWS domain DHHC PF01529.20 KKK16481.1 - 5.1e-34 117.3 4.2 5.1e-34 117.3 4.2 1.7 2 0 0 2 2 2 1 DHHC palmitoyltransferase ALMT PF11744.8 KKK16482.1 - 0.55 9.0 1.9 0.72 8.6 1.9 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Complex1_LYR PF05347.15 KKK16483.1 - 7.6e-16 57.9 5.1 7.6e-16 57.9 5.1 1.9 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KKK16483.1 - 0.087 13.6 2.4 0.23 12.3 2.4 1.7 1 0 0 1 1 1 0 Complex1_LYR-like TPR_12 PF13424.6 KKK16484.1 - 0.024 14.9 0.3 1.1 9.6 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat EGF PF00008.27 KKK16485.1 - 0.67 10.3 5.8 1.6 9.1 5.8 1.7 1 0 0 1 1 1 0 EGF-like domain WD40 PF00400.32 KKK16486.1 - 2.3e-08 34.5 4.9 0.0005 20.8 0.2 5.1 4 1 0 4 4 4 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKK16486.1 - 0.00045 20.5 0.0 16 5.9 0.0 4.2 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 KKK16486.1 - 0.013 14.3 0.1 0.13 10.9 0.0 2.1 2 0 0 2 2 2 0 Nup133 N terminal like Gryzun-like PF12742.7 KKK16486.1 - 0.026 14.5 0.0 0.048 13.7 0.0 1.4 1 0 0 1 1 1 0 Gryzun, putative Golgi trafficking Oxysterol_BP PF01237.18 KKK16486.1 - 0.14 10.9 3.3 0.25 10.1 3.3 1.3 1 0 0 1 1 1 0 Oxysterol-binding protein Csm1_N PF18504.1 KKK16486.1 - 0.99 9.8 5.5 1.8 9.0 0.9 2.6 1 1 1 2 2 2 0 Csm1 N-terminal domain Spc7 PF08317.11 KKK16486.1 - 2.5 6.9 10.1 3.6 6.4 10.1 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF4407 PF14362.6 KKK16486.1 - 3.4 6.9 8.8 5.3 6.3 8.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Atg14 PF10186.9 KKK16486.1 - 4.2 6.3 8.0 6.5 5.7 8.0 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 NIPSNAP PF07978.13 KKK16488.1 - 2e-40 137.1 5.8 4.5e-29 100.7 0.1 2.7 3 0 0 3 3 3 2 NIPSNAP FSH1 PF03959.13 KKK16489.1 - 1.1e-72 244.2 0.0 2.1e-72 243.2 0.0 1.4 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 KKK16489.1 - 0.0025 17.6 1.2 0.38 10.5 0.8 2.9 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase Esterase_phd PF10503.9 KKK16489.1 - 0.033 13.7 1.2 0.51 9.8 1.8 2.0 2 0 0 2 2 2 0 Esterase PHB depolymerase Hydrolase_4 PF12146.8 KKK16489.1 - 0.089 12.0 0.1 0.32 10.2 0.0 1.9 3 0 0 3 3 3 0 Serine aminopeptidase, S33 IMUP PF15761.5 KKK16489.1 - 0.27 11.9 4.7 0.6 10.8 4.7 1.6 1 0 0 1 1 1 0 Immortalisation up-regulated protein SR-25 PF10500.9 KKK16489.1 - 4.3 6.9 8.4 6.6 6.3 8.4 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Ribosomal_S27e PF01667.17 KKK16490.1 - 2.4e-27 94.4 6.9 4.4e-27 93.6 6.9 1.4 1 0 0 1 1 1 1 Ribosomal protein S27 CDP-OH_P_transf PF01066.21 KKK16490.1 - 1.7e-16 60.8 0.1 1.7e-16 60.8 0.1 3.4 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase TP_methylase PF00590.20 KKK16491.1 - 1.2e-48 165.9 0.0 1.9e-48 165.3 0.0 1.3 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_7 PF13241.6 KKK16491.1 - 9.9e-16 58.1 0.0 1.8e-15 57.2 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.6 KKK16491.1 - 5.7e-13 48.3 0.1 5.7e-09 35.5 0.1 2.6 2 0 0 2 2 2 2 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.6 KKK16491.1 - 1.4e-06 27.6 0.1 3.3e-06 26.4 0.1 1.7 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central DeoC PF01791.9 KKK16492.1 - 6.1e-12 45.7 2.2 8.4e-12 45.2 2.2 1.1 1 0 0 1 1 1 1 DeoC/LacD family aldolase DHO_dh PF01180.21 KKK16492.1 - 0.011 14.9 2.9 0.02 14.1 2.5 1.5 1 1 0 1 1 1 0 Dihydroorotate dehydrogenase FMN_dh PF01070.18 KKK16492.1 - 0.017 14.2 4.0 0.037 13.1 4.0 1.6 1 1 0 1 1 1 0 FMN-dependent dehydrogenase His_biosynth PF00977.21 KKK16492.1 - 0.027 13.9 0.2 0.055 12.9 0.2 1.5 1 0 0 1 1 1 0 Histidine biosynthesis protein DUF3375 PF11855.8 KKK16492.1 - 0.057 12.3 0.7 0.068 12.1 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3375) SelK_SelG PF10961.8 KKK16493.1 - 0.037 14.6 0.1 0.046 14.3 0.1 1.1 1 0 0 1 1 1 0 Selenoprotein SelK_SelG BPL_LplA_LipB PF03099.19 KKK16494.1 - 0.00015 21.7 0.0 0.00033 20.5 0.0 1.6 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Ras PF00071.22 KKK16495.1 - 5.5e-43 146.4 0.3 2.6e-42 144.2 0.3 1.8 1 1 0 1 1 1 1 Ras family Roc PF08477.13 KKK16495.1 - 3.4e-18 66.0 0.0 6.4e-18 65.1 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKK16495.1 - 4.9e-05 22.9 0.2 0.00034 20.1 0.2 1.9 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KKK16495.1 - 0.038 13.4 0.0 0.05 12.9 0.0 1.3 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_16 PF13191.6 KKK16495.1 - 0.057 13.8 0.0 0.079 13.3 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain Putative_PNPOx PF01243.20 KKK16496.1 - 5.6e-10 39.3 0.0 2.3e-09 37.3 0.0 2.0 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase Chordopox_G3 PF06129.12 KKK16496.1 - 0.061 14.0 0.0 0.1 13.3 0.0 1.3 1 0 0 1 1 1 0 Chordopoxvirus G3 protein PAPS_reduct PF01507.19 KKK16497.1 - 9.5e-44 149.5 0.1 2.2e-43 148.3 0.0 1.6 2 0 0 2 2 2 1 Phosphoadenosine phosphosulfate reductase family Ribosomal_S4e PF00900.20 KKK16498.1 - 8e-38 128.2 0.2 1.6e-37 127.2 0.2 1.5 1 0 0 1 1 1 1 Ribosomal family S4e 40S_S4_C PF16121.5 KKK16498.1 - 1.4e-24 85.5 0.0 2.4e-24 84.7 0.0 1.4 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus RS4NT PF08071.12 KKK16498.1 - 4.4e-18 65.1 6.6 8.3e-18 64.2 6.6 1.5 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.25 KKK16498.1 - 2.2e-06 27.3 0.0 4e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 S4 domain KOW PF00467.29 KKK16498.1 - 9.4e-05 22.2 4.1 9.4e-05 22.2 4.1 2.6 3 0 0 3 3 3 1 KOW motif PCI PF01399.27 KKK16499.1 - 1.9e-20 73.3 0.0 4.9e-20 72.0 0.0 1.7 1 0 0 1 1 1 1 PCI domain RPN5_C PF18098.1 KKK16499.1 - 2e-16 59.7 1.2 5e-16 58.5 1.2 1.7 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN5 C-terminal domain DUF2935 PF11155.8 KKK16499.1 - 0.42 10.9 2.0 0.91 9.9 0.0 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF2935) ERp29 PF07749.12 KKK16499.1 - 2.1 9.3 5.2 7.4 7.6 0.0 3.4 3 0 0 3 3 3 0 Endoplasmic reticulum protein ERp29, C-terminal domain PCI PF01399.27 KKK16500.1 - 1.7e-20 73.5 0.1 5.5e-20 71.8 0.1 1.9 1 0 0 1 1 1 1 PCI domain TPR_2 PF07719.17 KKK16500.1 - 0.0041 17.1 3.3 0.23 11.7 0.1 4.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 KKK16500.1 - 0.0053 16.5 0.9 0.47 10.4 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 KKK16500.1 - 0.014 15.3 0.6 1.2 9.3 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 KKK16500.1 - 0.042 13.5 0.5 0.25 11.1 0.1 2.6 2 0 0 2 2 2 0 TPR repeat ParD_antitoxin PF03693.14 KKK16500.1 - 0.14 12.6 0.0 0.68 10.4 0.0 2.1 2 0 0 2 2 2 0 Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH TPR_12 PF13424.6 KKK16500.1 - 0.16 12.3 0.7 9 6.7 0.0 3.6 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 KKK16500.1 - 0.61 11.1 2.9 23 6.2 0.0 4.1 4 1 1 5 5 5 0 Tetratricopeptide repeat ATP-sulfurylase PF01747.17 KKK16501.1 - 5e-87 290.8 0.0 7.5e-87 290.2 0.0 1.3 1 0 0 1 1 1 1 ATP-sulfurylase APS_kinase PF01583.20 KKK16501.1 - 3.5e-61 205.7 0.0 5.2e-61 205.2 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase PUA_2 PF14306.6 KKK16501.1 - 1.6e-51 174.1 0.0 2.8e-51 173.3 0.0 1.4 1 0 0 1 1 1 1 PUA-like domain AAA_18 PF13238.6 KKK16501.1 - 0.097 13.2 0.0 0.23 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.10 KKK16501.1 - 0.15 11.5 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 LIAS_N PF16881.5 KKK16502.1 - 1.1e-26 93.3 0.0 2.1e-26 92.5 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of lipoyl synthase of Radical_SAM family Radical_SAM PF04055.21 KKK16502.1 - 1.2e-14 55.0 0.0 1.8e-14 54.5 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily HAD PF12710.7 KKK16503.1 - 1.6e-19 71.0 0.0 2.2e-19 70.6 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KKK16503.1 - 6.6e-18 65.8 0.1 8.9e-18 65.3 0.1 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KKK16503.1 - 6.7e-08 32.6 0.0 2.3e-06 27.5 0.0 2.6 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 KKK16503.1 - 5.4e-05 22.7 0.0 0.00022 20.7 0.0 1.8 1 1 0 1 1 1 1 Putative Phosphatase HAD_2 PF13419.6 KKK16503.1 - 0.00036 20.7 0.2 0.24 11.5 0.0 2.7 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase DUF705 PF05152.12 KKK16503.1 - 0.012 15.1 0.1 0.018 14.6 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF705) S6PP PF05116.13 KKK16503.1 - 0.027 14.0 0.1 0.3 10.6 0.0 2.1 2 0 0 2 2 2 0 Sucrose-6F-phosphate phosphohydrolase Semialdhyde_dhC PF02774.18 KKK16504.1 - 3.4e-32 112.0 0.0 4.5e-32 111.6 0.0 1.2 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 KKK16504.1 - 6.2e-30 104.1 0.0 1.3e-29 103.1 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 KKK16504.1 - 0.037 14.3 0.0 0.13 12.5 0.0 1.8 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain DXP_reductoisom PF02670.16 KKK16504.1 - 0.12 13.1 0.0 0.31 11.8 0.0 1.8 2 0 0 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase FAD-oxidase_C PF02913.19 KKK16505.1 - 3.5e-63 213.6 0.0 4.5e-63 213.2 0.0 1.1 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 KKK16505.1 - 1.5e-34 118.7 0.0 2.8e-34 117.8 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain SepSecS PF05889.13 KKK16505.1 - 0.16 10.7 0.1 0.32 9.6 0.1 1.4 2 0 0 2 2 2 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Fez1 PF06818.15 KKK16506.1 - 0.00058 20.4 40.3 0.067 13.6 15.8 2.7 2 0 0 2 2 2 2 Fez1 Cast PF10174.9 KKK16506.1 - 0.0028 16.0 22.1 0.0028 16.0 22.1 2.7 2 1 1 3 3 3 1 RIM-binding protein of the cytomatrix active zone Golgin_A5 PF09787.9 KKK16506.1 - 0.0059 16.1 52.9 0.34 10.3 22.7 3.3 1 1 2 3 3 3 2 Golgin subfamily A member 5 Alkyl_sulf_C PF14864.6 KKK16506.1 - 0.014 15.6 0.1 0.034 14.4 0.1 1.6 1 0 0 1 1 1 0 Alkyl sulfatase C-terminal Rsa3 PF14615.6 KKK16506.1 - 0.036 13.6 0.3 0.1 12.2 0.3 1.7 1 0 0 1 1 1 0 Ribosome-assembly protein 3 Spc7 PF08317.11 KKK16506.1 - 0.22 10.3 53.4 0.5 9.2 13.1 3.3 1 1 2 3 3 3 0 Spc7 kinetochore protein TPR_MLP1_2 PF07926.12 KKK16506.1 - 3.1 7.9 54.4 3.3 7.8 10.1 4.4 1 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein RdRP PF05183.12 KKK16507.1 - 3.1e-156 521.4 0.0 2e-130 436.2 0.0 2.3 1 1 1 2 2 2 2 RNA dependent RNA polymerase RRM_1 PF00076.22 KKK16507.1 - 0.015 15.1 0.0 0.048 13.5 0.0 1.9 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DNA_pol_B PF00136.21 KKK16508.1 - 1e-104 350.8 0.0 1.4e-104 350.4 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 KKK16508.1 - 5.5e-19 68.5 0.2 3.6e-12 46.1 0.0 2.4 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 KKK16508.1 - 2.1e-17 63.4 7.5 2.1e-17 63.4 7.5 2.2 2 0 0 2 2 2 1 C4-type zinc-finger of DNA polymerase delta zf-RRPl_C4 PF17026.5 KKK16508.1 - 0.98 9.6 3.8 2.4 8.3 3.8 1.6 1 0 0 1 1 1 0 Putative ribonucleoprotein zinc-finger pf C4 type Slu7 PF11708.8 KKK16509.1 - 1.4e-84 284.1 16.4 1.4e-84 284.1 16.4 1.8 2 0 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor Ribosomal_L37e PF01907.19 KKK16509.1 - 1.3e-12 47.7 3.7 1.3e-12 47.7 3.7 3.1 3 0 0 3 3 3 1 Ribosomal protein L37e zf-CCHC_4 PF14392.6 KKK16509.1 - 0.048 13.4 0.6 0.048 13.4 0.6 2.3 2 0 0 2 2 2 0 Zinc knuckle zf-HYPF PF07503.12 KKK16509.1 - 1.2 8.9 4.6 1.4 8.7 0.6 2.5 2 0 0 2 2 2 0 HypF finger ELP6 PF09807.9 KKK16510.1 - 3.5e-08 33.2 0.0 2.2e-05 24.0 0.0 2.2 2 0 0 2 2 2 2 Elongation complex protein 6 Fungal_trans PF04082.18 KKK16511.1 - 4.1e-26 91.6 0.1 5.9e-26 91.1 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK16511.1 - 8.9e-10 38.5 14.0 1.5e-09 37.8 14.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gal4_dimer PF03902.13 KKK16511.1 - 4.1e-05 23.6 0.5 9.8e-05 22.4 0.2 1.8 2 0 0 2 2 2 1 Gal4-like dimerisation domain Peptidase_C65 PF10275.9 KKK16512.1 - 3.2e-54 184.0 0.0 3.8e-54 183.7 0.0 1.1 1 0 0 1 1 1 1 Peptidase C65 Otubain Zn_clus PF00172.18 KKK16519.1 - 5.8e-09 35.9 9.6 1.1e-08 35.0 9.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KKK16519.1 - 0.0046 16.0 0.1 0.013 14.6 0.1 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Sugar_tr PF00083.24 KKK16520.1 - 9.2e-28 97.3 23.1 1.6e-27 96.5 23.1 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKK16520.1 - 8.1e-14 51.3 31.1 8.1e-14 51.3 31.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily PhyH PF05721.13 KKK16521.1 - 2.3e-29 103.2 0.1 2.3e-29 103.2 0.1 1.4 2 0 0 2 2 2 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.6 KKK16521.1 - 0.00025 21.4 0.0 0.00052 20.4 0.0 1.6 1 0 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase 2OG-FeII_Oxy_3 PF13640.6 KKK16521.1 - 0.031 15.2 0.0 0.059 14.3 0.0 1.5 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Crystall PF00030.19 KKK16521.1 - 0.04 14.1 0.0 0.54 10.5 0.0 2.2 2 0 0 2 2 2 0 Beta/Gamma crystallin Phosphodiest PF01663.22 KKK16522.1 - 8e-28 98.0 0.0 1.2e-27 97.4 0.0 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase HD PF01966.22 KKK16522.1 - 8.7e-07 29.2 0.1 2e-06 28.0 0.1 1.6 1 0 0 1 1 1 1 HD domain HDOD PF08668.12 KKK16522.1 - 0.013 15.0 0.0 0.024 14.1 0.0 1.4 1 0 0 1 1 1 0 HDOD domain MIOX PF05153.15 KKK16522.1 - 0.05 13.2 0.0 0.08 12.5 0.0 1.2 1 0 0 1 1 1 0 Myo-inositol oxygenase CFEM PF05730.11 KKK16523.1 - 1.3e-15 57.3 13.9 2.4e-15 56.4 13.9 1.5 1 0 0 1 1 1 1 CFEM domain Rrp44_S1 PF17215.3 KKK16523.1 - 0.18 11.8 0.0 0.34 10.9 0.0 1.4 1 0 0 1 1 1 0 S1 domain GMC_oxred_N PF00732.19 KKK16524.1 - 4.9e-32 111.5 0.0 1.4e-28 100.1 0.0 2.4 2 1 0 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.13 KKK16524.1 - 1.1e-28 100.5 0.0 2.3e-28 99.5 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 KKK16524.1 - 0.00014 22.0 0.0 0.00039 20.6 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KKK16524.1 - 0.00023 20.5 0.0 0.00063 19.1 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KKK16524.1 - 0.00036 19.9 0.0 0.6 9.3 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KKK16524.1 - 0.0033 16.6 1.0 0.01 15.0 0.8 1.7 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 KKK16524.1 - 0.0052 15.9 0.0 0.0082 15.2 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein GIDA PF01134.22 KKK16524.1 - 0.017 14.2 0.2 0.52 9.3 0.1 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A HHH PF00633.23 KKK16524.1 - 0.03 14.2 0.6 4 7.5 0.0 3.0 3 0 0 3 3 3 0 Helix-hairpin-helix motif ApbA PF02558.16 KKK16524.1 - 0.033 13.8 0.2 0.069 12.8 0.2 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA HI0933_like PF03486.14 KKK16524.1 - 0.11 11.2 0.2 0.21 10.3 0.2 1.4 1 0 0 1 1 1 0 HI0933-like protein HHH_5 PF14520.6 KKK16524.1 - 0.14 12.8 0.1 3.7 8.2 0.1 2.7 1 1 0 1 1 1 0 Helix-hairpin-helix domain 3HCDH_N PF02737.18 KKK16524.1 - 0.2 11.5 0.0 0.52 10.2 0.0 1.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Peroxidase_2 PF01328.17 KKK16525.1 - 6e-47 160.6 0.0 8.3e-47 160.1 0.0 1.2 1 0 0 1 1 1 1 Peroxidase, family 2 Trehalase PF01204.18 KKK16526.1 - 1.6e-74 251.6 0.0 1.3e-42 146.4 0.5 2.2 2 0 0 2 2 2 2 Trehalase Trehalase_Ca-bi PF07492.11 KKK16526.1 - 2.3e-11 43.2 0.2 3.8e-11 42.5 0.2 1.4 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain GRDP-like PF07173.12 KKK16527.1 - 1.4e-20 74.4 1.9 4e-17 63.2 0.2 3.2 3 0 0 3 3 3 2 Glycine-rich domain-containing protein-like Bac_rhamnosid PF05592.11 KKK16528.1 - 0.027 14.4 0.0 0.064 13.2 0.0 1.6 1 0 0 1 1 1 0 Bacterial alpha-L-rhamnosidase concanavalin-like domain SKG6 PF08693.10 KKK16529.1 - 0.007 15.8 0.3 0.019 14.4 0.3 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain MFS_1 PF07690.16 KKK16530.1 - 2.3e-30 105.7 33.2 2.3e-30 105.7 33.2 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KKK16530.1 - 1.5e-12 47.2 6.1 1.5e-12 47.2 6.1 2.8 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.16 KKK16531.1 - 2e-50 171.7 39.4 2.9e-50 171.2 39.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KKK16531.1 - 2.4e-16 59.7 5.1 2.4e-16 59.7 5.1 2.7 3 0 0 3 3 3 1 Sugar (and other) transporter OATP PF03137.20 KKK16531.1 - 0.00035 19.0 6.5 0.00035 19.0 6.5 2.6 2 1 1 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family DUF2583 PF10762.9 KKK16531.1 - 4.2 7.9 6.5 0.75 10.3 1.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2583) FAD_binding_4 PF01565.23 KKK16532.1 - 9.4e-31 106.4 0.1 1.4e-30 105.9 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KKK16532.1 - 0.0013 18.7 0.1 0.0032 17.6 0.1 1.6 1 0 0 1 1 1 1 Berberine and berberine like Abhydrolase_1 PF00561.20 KKK16536.1 - 1.2e-13 51.3 0.2 2.3e-12 47.1 0.2 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KKK16536.1 - 2.5e-11 43.3 0.0 4.4e-10 39.2 0.0 2.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KKK16536.1 - 8.6e-11 42.8 0.3 1.8e-10 41.8 0.3 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.18 KKK16536.1 - 1.9e-05 24.3 0.4 1.6 8.2 0.0 3.2 3 0 0 3 3 3 3 Dienelactone hydrolase family FSH1 PF03959.13 KKK16536.1 - 0.0013 18.5 0.0 0.12 12.0 0.0 2.8 2 1 0 2 2 2 1 Serine hydrolase (FSH1) DUF2048 PF09752.9 KKK16536.1 - 0.02 14.0 0.2 0.082 12.0 0.5 1.8 2 0 0 2 2 2 0 Abhydrolase domain containing 18 BAAT_C PF08840.11 KKK16536.1 - 0.024 14.6 0.4 0.28 11.1 0.1 2.2 2 1 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Cas_Csy4 PF09618.10 KKK16537.1 - 0.062 13.4 0.3 0.074 13.2 0.3 1.0 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csy4) ANAPC4_WD40 PF12894.7 KKK16538.1 - 0.00025 21.3 0.0 1.4 9.2 0.0 3.0 2 1 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain RAB3GAP2_N PF14655.6 KKK16538.1 - 0.011 15.0 0.1 2.5 7.3 0.0 2.6 3 0 0 3 3 3 0 Rab3 GTPase-activating protein regulatory subunit N-terminus TFIIF_alpha PF05793.12 KKK16538.1 - 1.2 7.6 13.2 2.1 6.8 13.2 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) TLP-20 PF06088.11 KKK16538.1 - 1.6 8.6 4.6 0.35 10.7 1.3 1.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) CDC45 PF02724.14 KKK16538.1 - 2.6 6.2 9.0 4.1 5.6 9.0 1.2 1 0 0 1 1 1 0 CDC45-like protein Glyco_hydro_7 PF00840.20 KKK16539.1 - 1.7e-203 676.2 15.0 1.9e-203 676.0 15.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 APG5 PF04106.12 KKK16540.1 - 2.6e-34 118.8 0.0 3.9e-34 118.2 0.0 1.2 1 0 0 1 1 1 1 Autophagy protein Apg5 MFMR_assoc PF16596.5 KKK16559.1 - 7.8 7.0 12.7 0.95 9.9 7.6 2.1 2 0 0 2 2 2 0 Disordered region downstream of MFMR ABC_tran PF00005.27 KKK16560.1 - 7.6e-26 91.3 0.1 1.2e-25 90.6 0.1 1.3 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.24 KKK16560.1 - 1.6e-25 89.8 26.8 2.4e-25 89.2 26.8 1.2 1 0 0 1 1 1 1 ABC-2 type transporter RsgA_GTPase PF03193.16 KKK16560.1 - 3.8e-06 26.9 0.2 0.00018 21.5 0.0 2.6 3 0 0 3 3 3 1 RsgA GTPase AAA_16 PF13191.6 KKK16560.1 - 7.2e-06 26.5 0.0 1.4e-05 25.6 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 KKK16560.1 - 2.1e-05 24.2 0.0 3.7e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_21 PF13304.6 KKK16560.1 - 4.2e-05 23.5 0.3 0.15 11.8 0.0 2.9 2 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KKK16560.1 - 0.00052 19.5 0.0 0.0011 18.5 0.0 1.4 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA PF00004.29 KKK16560.1 - 0.00055 20.4 0.1 0.0023 18.4 0.1 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 KKK16560.1 - 0.0012 18.8 0.0 0.0032 17.4 0.0 1.7 2 0 0 2 2 1 1 Rad17 P-loop domain NACHT PF05729.12 KKK16560.1 - 0.0045 16.9 0.0 0.0089 16.0 0.0 1.5 1 0 0 1 1 1 1 NACHT domain IstB_IS21 PF01695.17 KKK16560.1 - 0.0078 16.0 0.1 0.022 14.5 0.0 1.7 2 0 0 2 2 1 1 IstB-like ATP binding protein AAA_18 PF13238.6 KKK16560.1 - 0.0078 16.8 0.1 0.017 15.7 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 KKK16560.1 - 0.0099 16.1 0.4 0.018 15.3 0.4 1.4 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 KKK16560.1 - 0.011 15.7 0.0 0.019 14.9 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 KKK16560.1 - 0.011 16.1 0.0 0.032 14.6 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_22 PF13401.6 KKK16560.1 - 0.011 16.0 0.0 0.024 14.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_13 PF13166.6 KKK16560.1 - 0.011 14.4 0.9 0.019 13.6 0.1 1.6 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 KKK16560.1 - 0.012 15.6 0.0 0.029 14.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 KKK16560.1 - 0.02 15.0 0.1 0.046 13.8 0.1 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_30 PF13604.6 KKK16560.1 - 0.024 14.3 0.1 0.048 13.4 0.1 1.4 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.12 KKK16560.1 - 0.03 14.1 0.0 0.064 13.0 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain NTPase_1 PF03266.15 KKK16560.1 - 0.045 13.7 0.2 0.12 12.3 0.0 1.8 2 0 0 2 2 2 0 NTPase AAA_33 PF13671.6 KKK16560.1 - 0.083 13.0 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 KKK16560.1 - 0.086 11.9 0.1 0.14 11.2 0.1 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein ATP-synt_ab PF00006.25 KKK16560.1 - 0.1 12.2 0.1 0.2 11.3 0.1 1.5 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_35 PF14516.6 KKK16560.1 - 0.11 11.3 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain TsaE PF02367.17 KKK16560.1 - 0.12 12.4 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_29 PF13555.6 KKK16560.1 - 0.12 12.1 0.0 0.29 10.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain PduV-EutP PF10662.9 KKK16560.1 - 0.15 11.8 0.0 0.37 10.5 0.0 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_23 PF13476.6 KKK16560.1 - 0.15 12.5 0.1 0.32 11.5 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 KKK16560.1 - 0.19 11.7 0.1 0.44 10.5 0.1 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) tRNA-synt_1d PF00750.19 KKK16561.1 - 1.1e-100 337.0 1.7 1.7e-100 336.3 1.7 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 KKK16561.1 - 4.6e-28 97.8 0.0 1.1e-27 96.6 0.0 1.7 1 0 0 1 1 1 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.16 KKK16561.1 - 3e-05 24.5 0.1 9.9e-05 22.9 0.0 2.0 2 0 0 2 2 2 1 Arginyl tRNA synthetase N terminal domain Acyl_transf_1 PF00698.21 KKK16568.1 - 2.5e-18 66.7 0.0 7.3e-12 45.4 0.0 2.1 2 0 0 2 2 2 2 Acyl transferase domain DUF4948 PF16306.5 KKK16568.1 - 0.013 15.3 0.0 0.032 14.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4948) Nucleoporin_C PF03177.14 KKK16569.1 - 1.1e-175 585.9 7.7 1.3e-175 585.6 7.7 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.11 KKK16569.1 - 4.4e-75 253.1 0.0 6.7e-75 252.5 0.0 1.3 1 0 0 1 1 1 1 Nup133 N terminal like IF-2B PF01008.17 KKK16570.1 - 3.8e-74 249.4 0.3 4.4e-74 249.2 0.3 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family zf-HC2 PF13490.6 KKK16571.1 - 0.19 12.0 0.7 0.31 11.3 0.7 1.4 1 0 0 1 1 1 0 Putative zinc-finger zf-4CXXC_R1 PF10497.9 KKK16572.1 - 1.6e-08 34.7 12.3 1.6e-08 34.7 12.3 2.6 2 0 0 2 2 2 1 Zinc-finger domain of monoamine-oxidase A repressor R1 JmjC PF02373.22 KKK16572.1 - 3.2e-08 34.0 0.2 3.2e-07 30.8 0.2 2.5 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_2 PF07883.11 KKK16572.1 - 0.0099 15.6 0.0 0.033 13.9 0.0 1.8 2 0 0 2 2 2 1 Cupin domain UbiA PF01040.18 KKK16573.1 - 5.2e-45 153.7 16.9 7e-45 153.3 16.9 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Flavoprotein PF02441.19 KKK16574.1 - 7.2e-42 142.8 0.0 9.6e-42 142.4 0.0 1.2 1 0 0 1 1 1 1 Flavoprotein ATPase_2 PF01637.18 KKK16574.1 - 0.17 11.8 0.0 0.27 11.1 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Ank_2 PF12796.7 KKK16575.1 - 2.6e-36 124.1 12.1 1e-10 42.0 0.1 4.6 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KKK16575.1 - 6e-22 77.7 9.1 7.1e-08 32.8 0.1 5.8 1 1 4 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KKK16575.1 - 1.4e-17 62.0 3.4 0.0087 16.5 0.0 6.9 7 0 0 7 7 7 4 Ankyrin repeat Ank_5 PF13857.6 KKK16575.1 - 1.1e-16 60.7 5.1 0.00091 19.5 0.1 5.6 2 2 3 5 5 5 4 Ankyrin repeats (many copies) SPX PF03105.19 KKK16575.1 - 2.9e-16 60.4 12.3 1.3e-05 25.3 3.3 3.2 1 1 2 3 3 3 3 SPX domain GDPD PF03009.17 KKK16575.1 - 1.7e-12 47.6 0.0 4e-12 46.4 0.0 1.6 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Ank PF00023.30 KKK16575.1 - 8.1e-12 45.0 8.2 0.015 15.8 0.0 6.4 7 0 0 7 7 7 4 Ankyrin repeat DUF1279 PF06916.13 KKK16576.1 - 1.6e-24 86.3 0.0 2.9e-24 85.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) Ribosomal_L3 PF00297.22 KKK16577.1 - 1.2e-16 60.7 4.9 1.2e-13 50.8 1.5 2.1 1 1 1 2 2 2 2 Ribosomal protein L3 Coa1 PF08695.10 KKK16578.1 - 8.5e-32 109.3 0.1 1.1e-31 109.0 0.1 1.1 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 DUF4307 PF14155.6 KKK16578.1 - 0.16 11.8 0.0 0.21 11.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4307) Oxidored_q6 PF01058.22 KKK16579.1 - 3.9e-22 78.5 0.0 6.2e-22 77.8 0.0 1.3 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Mpp10 PF04006.12 KKK16580.1 - 2.9e-105 353.0 31.6 4.3e-105 352.5 31.6 1.2 1 0 0 1 1 1 1 Mpp10 protein Methyltransf_16 PF10294.9 KKK16581.1 - 1.5e-46 158.3 0.0 2.1e-46 157.8 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Met_10 PF02475.16 KKK16581.1 - 0.071 12.8 0.0 0.57 9.9 0.0 1.9 2 0 0 2 2 2 0 Met-10+ like-protein DUF1761 PF08570.10 KKK16582.1 - 6.3e-27 94.3 4.6 7.2e-27 94.1 4.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1761) Kinocilin PF15033.6 KKK16582.1 - 3.1 7.4 6.9 2.4 7.8 0.2 2.4 1 1 1 2 2 2 0 Kinocilin protein AhpC-TSA PF00578.21 KKK16584.1 - 1.5e-22 79.8 0.0 2.9e-22 78.9 0.0 1.5 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KKK16584.1 - 1.4e-11 44.3 0.0 1.9e-11 43.9 0.0 1.2 1 0 0 1 1 1 1 Redoxin DUF4677 PF15726.5 KKK16584.1 - 0.034 14.3 0.0 0.064 13.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4677) PRELI PF04707.14 KKK16585.1 - 4e-45 153.4 0.3 4.7e-45 153.2 0.3 1.0 1 0 0 1 1 1 1 PRELI-like family CTP_transf_like PF01467.26 KKK16587.1 - 7e-26 91.1 0.0 6e-23 81.6 0.0 2.7 3 0 0 3 3 3 2 Cytidylyltransferase-like Glutaredoxin PF00462.24 KKK16588.1 - 6.6e-15 55.1 0.0 1.1e-14 54.4 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin Cwf_Cwc_15 PF04889.12 KKK16595.1 - 1.9e-81 273.5 12.5 3.1e-81 272.8 12.5 1.3 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein Med22 PF06179.12 KKK16595.1 - 7.4e-18 64.7 3.3 7.4e-18 64.7 3.3 2.2 2 1 1 3 3 3 1 Surfeit locus protein 5 subunit 22 of Mediator complex CDC45 PF02724.14 KKK16595.1 - 0.2 9.9 9.7 0.24 9.7 9.7 1.1 1 0 0 1 1 1 0 CDC45-like protein PdaC PF13739.6 KKK16595.1 - 0.48 11.4 2.3 6.1 7.9 0.0 2.5 2 0 0 2 2 2 0 Deacetylase PdaC RNase_PH PF01138.21 KKK16596.1 - 1.2e-16 61.4 0.0 1.8e-16 60.8 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KKK16596.1 - 9.1e-06 25.6 0.0 1.9e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 DHFR_1 PF00186.19 KKK16597.1 - 5.1e-18 65.3 0.1 8.1e-07 28.9 0.1 3.2 2 1 1 3 3 3 3 Dihydrofolate reductase CAP_N PF01213.19 KKK16597.1 - 6.1 6.2 5.3 8.8 5.7 5.3 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal PhoLip_ATPase_C PF16212.5 KKK16598.1 - 5.9e-81 271.9 16.1 5.9e-81 271.9 16.1 1.8 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KKK16598.1 - 6.2e-25 86.7 7.5 1.9e-24 85.2 7.5 1.9 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 KKK16598.1 - 8.2e-11 41.9 0.0 3.2e-10 40.0 0.0 1.9 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KKK16598.1 - 5.4e-10 39.9 1.8 1.3e-05 25.6 0.5 3.3 1 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 KKK16598.1 - 1.1e-05 25.0 0.0 2.8e-05 23.7 0.0 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KKK16598.1 - 0.0057 16.4 0.0 0.019 14.7 0.0 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF2838 PF10998.8 KKK16604.1 - 5.9e-41 139.2 11.7 5.9e-41 139.2 11.7 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2838) Tropomyosin_1 PF12718.7 KKK16604.1 - 0.0047 17.1 0.9 0.0082 16.3 0.9 1.3 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.20 KKK16604.1 - 0.11 11.9 2.3 0.17 11.2 2.3 1.3 1 0 0 1 1 1 0 Tropomyosin Exonuc_VII_L PF02601.15 KKK16604.1 - 0.14 11.7 0.1 0.18 11.3 0.1 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Atg14 PF10186.9 KKK16604.1 - 0.2 10.7 2.1 0.3 10.1 2.1 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Val_tRNA-synt_C PF10458.9 KKK16604.1 - 1.5 9.1 7.6 6.7 7.1 0.1 2.4 2 0 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm LETM1 PF07766.13 KKK16605.1 - 7.7e-103 343.5 0.1 7.7e-103 343.5 0.1 1.6 2 0 0 2 2 2 1 LETM1-like protein SAP PF02037.27 KKK16605.1 - 0.00036 20.2 0.0 0.0061 16.3 0.0 2.8 3 0 0 3 3 3 1 SAP domain FAA_hydrolase PF01557.18 KKK16607.1 - 1.1e-50 172.4 0.0 1.2e-50 172.2 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family PWI PF01480.17 KKK16608.1 - 1.7e-29 101.9 0.0 3e-29 101.1 0.0 1.4 1 0 0 1 1 1 1 PWI domain Cupin_8 PF13621.6 KKK16609.1 - 5.8e-15 55.7 0.1 1e-11 45.1 0.0 2.2 1 1 1 2 2 2 2 Cupin-like domain JmjC PF02373.22 KKK16609.1 - 5.3e-10 39.7 0.3 9.9e-09 35.6 0.3 2.4 1 1 0 1 1 1 1 JmjC domain, hydroxylase F-box-like PF12937.7 KKK16609.1 - 7.8e-07 28.9 0.1 1.6e-06 27.9 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KKK16609.1 - 2.3e-05 24.2 0.0 5.5e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 F-box domain DUF3545 PF12065.8 KKK16609.1 - 0.16 12.0 0.2 0.27 11.3 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3545) DEAD PF00270.29 KKK16610.1 - 2.6e-46 157.6 0.6 5.3e-46 156.6 0.6 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KKK16610.1 - 9.6e-32 109.6 0.3 5e-31 107.3 0.1 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KKK16610.1 - 6e-06 26.4 0.0 1e-05 25.6 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 KKK16610.1 - 0.00061 19.6 0.1 0.0013 18.5 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KKK16610.1 - 0.001 19.4 0.5 0.0069 16.7 0.2 2.1 2 1 0 2 2 2 1 AAA domain CMS1 PF14617.6 KKK16610.1 - 0.0041 16.5 0.0 0.009 15.4 0.0 1.5 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit AAA_22 PF13401.6 KKK16610.1 - 0.012 15.9 1.2 0.073 13.3 1.2 2.2 1 1 0 1 1 1 0 AAA domain fragilysinNterm PF16376.5 KKK16610.1 - 0.096 12.4 0.1 0.32 10.7 0.0 1.9 2 0 0 2 2 2 0 N-terminal domain of fragilysin Helicase_RecD PF05127.14 KKK16610.1 - 0.12 12.2 0.0 0.26 11.1 0.0 1.6 1 1 0 1 1 1 0 Helicase NuA4 PF09340.10 KKK16611.1 - 3.1e-28 97.5 0.9 3.1e-28 97.5 0.9 1.8 2 0 0 2 2 2 1 Histone acetyltransferase subunit NuA4 DUF5320 PF17253.2 KKK16611.1 - 0.019 16.0 2.0 0.053 14.6 1.2 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5320) Ctr PF04145.15 KKK16612.1 - 5.1e-31 108.3 1.0 6e-31 108.1 1.0 1.1 1 0 0 1 1 1 1 Ctr copper transporter family Glyco_hydro_38N PF01074.22 KKK16614.1 - 7.9e-89 297.8 1.3 7.9e-89 297.8 1.3 1.9 3 0 0 3 3 3 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 KKK16614.1 - 1.3e-59 201.9 0.0 7.2e-59 199.4 0.0 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 KKK16614.1 - 1.4e-26 92.4 0.0 2.8e-26 91.5 0.0 1.5 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 KKK16614.1 - 1e-06 28.8 0.0 2.3e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain Glyco_hydro_57 PF03065.15 KKK16614.1 - 0.13 11.5 0.0 0.32 10.1 0.0 1.7 1 1 0 1 1 1 0 Glycosyl hydrolase family 57 GUN4 PF05419.12 KKK16614.1 - 1.9 8.6 4.8 3.3 7.8 0.1 3.1 4 0 0 4 4 4 0 GUN4-like Glyco_hydro_18 PF00704.28 KKK16615.1 - 5.1e-36 125.0 0.2 7e-36 124.5 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 LysM PF01476.20 KKK16615.1 - 1.6e-08 34.4 0.0 0.00012 22.0 0.0 2.8 2 0 0 2 2 2 2 LysM domain Chitin_bind_1 PF00187.19 KKK16615.1 - 0.0002 21.8 7.2 0.0002 21.8 7.2 3.2 4 0 0 4 4 4 1 Chitin recognition protein Amidohydro_1 PF01979.20 KKK16616.1 - 8.1e-14 51.7 0.0 1.6e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KKK16616.1 - 4.7e-09 36.2 0.0 5.4e-09 36.0 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family ATG22 PF11700.8 KKK16617.1 - 5.4e-166 552.9 5.6 2.1e-132 442.1 2.7 2.0 1 1 1 2 2 2 2 Vacuole effluxer Atg22 like MFS_1 PF07690.16 KKK16617.1 - 1.1e-05 24.6 18.9 1.1e-05 24.6 18.9 3.3 3 1 1 4 4 4 2 Major Facilitator Superfamily BT1 PF03092.16 KKK16617.1 - 0.083 11.1 7.7 0.13 10.4 1.7 2.4 2 1 0 2 2 2 0 BT1 family DUF5493 PF17597.2 KKK16617.1 - 1.2 9.5 8.7 5.2 7.4 4.4 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5493) PBP PF01161.20 KKK16618.1 - 8.6e-20 71.4 0.0 1.1e-19 71.0 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein GFA PF04828.14 KKK16619.1 - 9.4e-24 83.6 0.0 1.4e-23 83.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme DZR PF12773.7 KKK16619.1 - 0.11 12.6 3.3 0.83 9.7 0.2 2.5 2 1 0 2 2 2 0 Double zinc ribbon Nudix_N_2 PF14803.6 KKK16619.1 - 0.4 10.7 0.0 0.4 10.7 0.0 2.8 3 0 0 3 3 3 0 Nudix N-terminal Zn_clus PF00172.18 KKK16620.1 - 1e-08 35.2 7.3 4.4e-08 33.1 7.3 2.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain OPT PF03169.15 KKK16621.1 - 2.1e-184 614.6 54.0 2.4e-184 614.4 54.0 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein NADH_B2 PF14813.6 KKK16621.1 - 0.27 11.1 7.6 7.2 6.5 0.1 3.7 3 0 0 3 3 3 0 NADH dehydrogenase 1 beta subcomplex subunit 2 p450 PF00067.22 KKK16622.1 - 2.3e-105 353.0 0.0 2.6e-105 352.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 PBP PF01161.20 KKK16624.1 - 1.5e-10 41.5 0.1 3.2e-10 40.4 0.1 1.5 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Zn_clus PF00172.18 KKK16624.1 - 2.6e-08 33.8 11.0 9.3e-08 32.1 11.0 2.0 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 KKK16625.1 - 2.7e-45 154.8 22.7 2.7e-45 154.8 22.7 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KKK16625.1 - 2.2e-10 40.0 6.8 2.2e-10 40.0 6.8 2.2 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KKK16625.1 - 1.6e-05 23.6 3.2 1.6e-05 23.6 3.2 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.7 KKK16625.1 - 0.0034 16.3 0.0 0.025 13.4 0.0 2.3 1 1 0 1 1 1 1 MFS_1 like family MFS_5 PF05631.14 KKK16625.1 - 0.047 12.6 5.8 0.033 13.1 2.3 2.1 2 0 0 2 2 2 0 Sugar-tranasporters, 12 TM TEX12 PF15219.6 KKK16625.1 - 0.22 11.9 0.1 0.53 10.6 0.0 1.6 1 1 1 2 2 2 0 Testis-expressed 12 CPP1-like PF11833.8 KKK16625.1 - 0.26 10.9 3.5 12 5.5 4.1 2.5 2 0 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Citrate_synt PF00285.21 KKK16626.1 - 2.8e-83 280.0 0.0 3.2e-83 279.8 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Fungal_trans PF04082.18 KKK16627.1 - 1e-38 132.9 0.0 1.6e-38 132.3 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK16627.1 - 1.2e-09 38.1 8.9 2.1e-09 37.4 8.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KKK16627.1 - 0.0064 15.3 0.0 0.011 14.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain VCX_VCY PF15231.6 KKK16627.1 - 0.034 14.8 1.9 0.085 13.5 1.9 1.6 1 0 0 1 1 1 0 Variable charge X/Y family MRI PF15325.6 KKK16627.1 - 1.9 9.6 5.0 15 6.7 2.1 2.6 2 0 0 2 2 2 0 Modulator of retrovirus infection RNA_pol PF00940.19 KKK16628.1 - 3.5e-181 602.6 0.0 5e-181 602.1 0.0 1.2 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.6 KKK16628.1 - 1.8e-91 307.1 0.3 2.8e-91 306.4 0.3 1.3 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal Ras PF00071.22 KKK16629.1 - 3.1e-59 199.2 0.2 4e-59 198.8 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KKK16629.1 - 3.9e-37 127.1 0.3 7.9e-37 126.1 0.1 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKK16629.1 - 1.6e-17 63.5 0.1 1.9e-17 63.3 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KKK16629.1 - 3.1e-06 26.8 0.0 4.5e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 KKK16629.1 - 4.5e-06 26.3 0.1 2.9e-05 23.7 0.1 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KKK16629.1 - 6.5e-06 26.1 0.2 0.0057 16.6 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 KKK16629.1 - 1.5e-05 25.1 0.0 2.5e-05 24.3 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KKK16629.1 - 3.9e-05 23.1 0.2 4.8e-05 22.8 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region TIR_2 PF13676.6 KKK16629.1 - 0.079 13.6 0.0 0.13 12.8 0.0 1.4 1 0 0 1 1 1 0 TIR domain AAA_7 PF12775.7 KKK16629.1 - 0.091 12.3 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Dynamin_N PF00350.23 KKK16629.1 - 0.11 12.6 0.1 9 6.3 0.0 2.6 2 1 1 3 3 3 0 Dynamin family ATP-synt_C PF00137.21 KKK16630.1 - 1.2e-24 86.4 27.9 3.5e-14 52.9 11.3 2.4 2 0 0 2 2 2 2 ATP synthase subunit C SLATT_5 PF18160.1 KKK16630.1 - 0.56 9.5 1.9 0.62 9.3 0.1 1.8 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 NIR_SIR PF01077.22 KKK16631.1 - 1.3e-49 167.7 0.0 2.1e-44 150.8 0.0 2.4 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.17 KKK16631.1 - 8.4e-30 102.4 0.0 5.3e-14 51.8 0.0 2.7 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.25 KKK16631.1 - 4.8e-26 91.7 0.0 1.1e-25 90.5 0.0 1.7 1 0 0 1 1 1 1 Flavodoxin Sin_N PF04801.13 KKK16631.1 - 4.7e-19 68.9 0.0 6.1e-12 45.5 0.0 2.1 2 0 0 2 2 2 2 Sin-like protein conserved region POR_N PF01855.19 KKK16631.1 - 8e-08 32.3 1.7 1.5e-07 31.4 0.4 2.1 2 0 0 2 2 2 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg GARS_C PF02843.16 KKK16631.1 - 0.13 12.5 0.1 3.2 8.1 0.1 2.9 2 0 0 2 2 2 0 Phosphoribosylglycinamide synthetase, C domain Kei1 PF08552.11 KKK16632.1 - 3.1e-67 226.2 1.2 3.8e-67 225.9 1.2 1.1 1 0 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 DUF4875 PF16175.5 KKK16632.1 - 0.18 11.9 0.0 0.32 11.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4875) DDHD PF02862.17 KKK16633.1 - 4.9e-26 92.3 0.1 4.7e-23 82.5 0.0 2.8 2 1 0 2 2 2 1 DDHD domain Abhydrolase_6 PF12697.7 KKK16633.1 - 0.29 11.7 4.0 0.3 11.6 0.0 2.6 3 0 0 3 3 3 0 Alpha/beta hydrolase family LSM PF01423.22 KKK16637.1 - 1.3e-16 60.0 0.9 1.8e-16 59.6 0.9 1.2 1 0 0 1 1 1 1 LSM domain LRR_9 PF14580.6 KKK16637.1 - 0.014 14.9 0.2 0.02 14.4 0.2 1.3 1 0 0 1 1 1 0 Leucine-rich repeat Hfq PF17209.3 KKK16637.1 - 0.05 13.2 0.1 0.1 12.3 0.1 1.5 1 0 0 1 1 1 0 Hfq protein DRMBL PF07522.14 KKK16638.1 - 2.1e-35 121.2 0.0 4.9e-35 120.0 0.0 1.7 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.7 KKK16638.1 - 8.7e-09 35.2 0.0 1.8e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain SH3BGR PF04908.15 KKK16639.1 - 0.0026 17.9 0.0 0.011 15.9 0.0 2.1 2 0 0 2 2 2 1 SH3-binding, glutamic acid-rich protein Ndc1_Nup PF09531.10 KKK16639.1 - 2.6 6.6 8.8 3.2 6.3 8.8 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Pneumo_att_G PF05539.11 KKK16639.1 - 8.5 5.9 8.7 10 5.6 8.7 1.2 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G Ribul_P_3_epim PF00834.19 KKK16640.1 - 9.6e-62 207.9 0.0 1.1e-60 204.4 0.0 2.0 1 1 0 1 1 1 1 Ribulose-phosphate 3 epimerase family ThiG PF05690.14 KKK16640.1 - 0.015 14.6 0.1 0.023 14.0 0.1 1.2 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG QRPTase_C PF01729.19 KKK16640.1 - 0.024 14.4 0.1 1.2 8.9 0.0 2.2 2 0 0 2 2 2 0 Quinolinate phosphoribosyl transferase, C-terminal domain OMPdecase PF00215.24 KKK16640.1 - 0.056 13.0 0.0 0.083 12.5 0.0 1.5 1 1 0 1 1 1 0 Orotidine 5'-phosphate decarboxylase / HUMPS family Methyltransf_11 PF08241.12 KKK16641.1 - 6.2e-08 33.2 0.0 1.5e-07 32.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKK16641.1 - 0.0053 17.4 0.0 0.014 16.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KKK16641.1 - 0.13 12.1 0.0 0.37 10.6 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain adh_short_C2 PF13561.6 KKK16643.1 - 2e-63 214.1 0.2 2.4e-63 213.8 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KKK16643.1 - 2.4e-43 147.9 0.2 2.9e-43 147.6 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KKK16643.1 - 2.8e-13 50.2 0.1 4e-13 49.7 0.1 1.2 1 0 0 1 1 1 1 KR domain GH131_N PF18271.1 KKK16644.1 - 6.4e-53 180.0 0.2 8.3e-53 179.7 0.2 1.1 1 0 0 1 1 1 1 Glycoside hydrolase 131 catalytic N-terminal domain PAS_9 PF13426.7 KKK16645.1 - 5.6e-15 55.5 0.1 5.5e-13 49.1 0.0 2.9 3 0 0 3 3 3 1 PAS domain SUIM_assoc PF16619.5 KKK16645.1 - 0.00012 22.0 3.3 0.00012 22.0 3.3 3.0 3 0 0 3 3 2 1 Unstructured region C-term to UIM in Ataxin3 PAS_4 PF08448.10 KKK16645.1 - 0.00018 21.8 1.9 0.31 11.3 0.0 3.4 3 0 0 3 3 3 2 PAS fold PAS PF00989.25 KKK16645.1 - 0.00096 19.1 9.8 0.0011 18.9 0.0 3.7 4 0 0 4 4 4 1 PAS fold PAS_3 PF08447.12 KKK16645.1 - 0.0091 16.3 0.1 0.48 10.8 0.0 2.9 2 0 0 2 2 2 1 PAS fold DUF2844 PF11005.8 KKK16645.1 - 0.013 15.5 0.1 0.013 15.5 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2844) Spt20 PF12090.8 KKK16645.1 - 0.02 14.5 19.7 0.046 13.3 19.7 1.5 1 0 0 1 1 1 0 Spt20 family TFIIA PF03153.13 KKK16645.1 - 0.051 13.6 22.3 0.09 12.8 22.3 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Lin-8 PF03353.15 KKK16645.1 - 0.13 11.8 14.4 3.6 7.1 12.6 2.3 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist Na_trans_assoc PF06512.13 KKK16645.1 - 0.16 12.2 6.9 0.34 11.2 6.9 1.5 1 0 0 1 1 1 0 Sodium ion transport-associated BAF1_ABF1 PF04684.13 KKK16645.1 - 0.22 10.5 13.5 0.018 14.1 9.0 1.4 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor FGF-BP1 PF06473.12 KKK16645.1 - 1.4 8.7 13.4 2.8 7.7 13.4 1.4 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) RskA PF10099.9 KKK16645.1 - 1.5 9.0 6.1 3.7 7.8 6.0 1.6 1 1 0 1 1 1 0 Anti-sigma-K factor rskA Neur_chan_memb PF02932.16 KKK16645.1 - 1.6 8.7 5.6 1.6 8.8 3.9 1.9 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region O-antigen_lig PF13425.6 KKK16645.1 - 1.9 7.2 9.5 2.7 6.7 9.5 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Presenilin PF01080.17 KKK16645.1 - 2.5 6.8 16.7 3.6 6.3 13.9 2.0 2 0 0 2 2 2 0 Presenilin ASD2 PF08687.11 KKK16645.1 - 4.2 6.8 17.6 0.99 8.9 14.2 1.6 2 0 0 2 2 2 0 Apx/Shroom domain ASD2 Asp-B-Hydro_N PF05279.11 KKK16645.1 - 5.9 6.9 14.6 10 6.1 14.6 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region FAM60A PF15396.6 KKK16645.1 - 6.7 6.7 10.2 1.5 8.7 6.3 1.8 2 0 0 2 2 2 0 Protein Family FAM60A Hid1 PF12722.7 KKK16645.1 - 9.2 4.3 12.4 14 3.6 12.4 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein MFS_1 PF07690.16 KKK16646.1 - 1.5e-21 76.7 39.9 3.5e-19 68.9 26.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KKK16646.1 - 2.4e-06 26.7 15.1 3.5e-06 26.1 13.2 2.0 1 1 1 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KKK16646.1 - 1.5e-05 23.6 2.4 2.6e-05 22.9 2.4 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 KKK16646.1 - 2.8 6.1 6.6 10 4.2 1.2 2.9 3 0 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family TPR_2 PF07719.17 KKK16647.1 - 2e-13 49.3 1.9 0.0017 18.3 0.0 5.7 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_1 PF00515.28 KKK16647.1 - 3.7e-11 42.3 2.5 0.00048 19.8 0.0 5.3 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.6 KKK16647.1 - 8.5e-08 31.8 7.5 0.014 15.1 0.0 5.8 6 1 1 7 7 7 2 TPR repeat TPR_14 PF13428.6 KKK16647.1 - 1.8e-06 28.3 9.1 0.85 10.6 0.0 7.1 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_19 PF14559.6 KKK16647.1 - 2.7e-05 24.6 6.9 4.9 7.7 0.0 5.8 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.6 KKK16647.1 - 0.00012 22.7 17.7 0.88 10.3 0.0 6.4 7 1 0 7 7 7 3 Tetratricopeptide repeat TPR_8 PF13181.6 KKK16647.1 - 0.00061 19.8 0.5 21 5.6 0.0 5.9 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_12 PF13424.6 KKK16647.1 - 0.00069 19.9 6.6 0.032 14.5 0.2 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 KKK16647.1 - 0.0019 18.1 2.6 30 4.9 0.0 5.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_4 PF07721.14 KKK16647.1 - 0.0048 17.4 8.0 0.78 10.5 0.3 5.6 7 0 0 7 7 4 1 Tetratricopeptide repeat TPR_9 PF13371.6 KKK16647.1 - 0.031 14.4 2.5 23 5.2 0.0 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat LSM PF01423.22 KKK16648.1 - 3.2e-18 65.2 0.0 3.7e-18 65.0 0.0 1.1 1 0 0 1 1 1 1 LSM domain Tannase PF07519.11 KKK16650.1 - 4.8e-102 342.3 0.0 5.9e-102 342.0 0.0 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Peptidase_S9 PF00326.21 KKK16650.1 - 0.011 15.2 0.1 1.2 8.6 0.2 2.3 2 0 0 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 KKK16650.1 - 0.016 14.8 0.0 0.038 13.6 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KKK16650.1 - 0.17 11.2 0.0 0.36 10.1 0.0 1.6 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF866 PF05907.13 KKK16651.1 - 2.3e-62 209.5 0.9 2.6e-62 209.3 0.9 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) Zn_ribbon_SprT PF17283.2 KKK16651.1 - 0.49 10.3 4.0 9 6.3 0.2 2.3 2 0 0 2 2 2 0 SprT-like zinc ribbon domain FAD_binding_3 PF01494.19 KKK16652.1 - 1e-71 242.1 0.0 1.3e-71 241.7 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 KKK16652.1 - 2.3e-39 135.1 0.1 4.8e-39 134.0 0.1 1.5 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Pyr_redox_2 PF07992.14 KKK16652.1 - 0.0055 16.0 0.0 0.036 13.3 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KKK16652.1 - 0.0081 15.8 0.1 0.45 10.0 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase UDPG_MGDP_dh_N PF03721.14 KKK16652.1 - 0.03 13.9 0.1 0.31 10.6 0.1 2.1 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox PF00070.27 KKK16652.1 - 0.053 14.1 0.0 0.16 12.6 0.0 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase RIX1 PF08167.12 KKK16653.1 - 1.9e-59 200.6 3.0 4.3e-59 199.4 3.0 1.6 1 0 0 1 1 1 1 rRNA processing/ribosome biogenesis MMS19_N PF14500.6 KKK16653.1 - 0.073 12.6 0.7 0.51 9.9 0.0 2.6 3 0 0 3 3 3 0 Dos2-interacting transcription regulator of RNA-Pol-II TPR_14 PF13428.6 KKK16654.1 - 2.8e-10 40.1 25.4 0.36 11.8 0.1 8.9 10 0 0 10 10 8 4 Tetratricopeptide repeat TPR_2 PF07719.17 KKK16654.1 - 5.5e-10 38.6 9.4 0.024 14.7 0.1 6.7 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_1 PF00515.28 KKK16654.1 - 4e-07 29.6 7.3 0.0074 16.1 0.0 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 KKK16654.1 - 9.1e-07 28.6 8.6 3 8.3 0.0 6.4 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.6 KKK16654.1 - 0.0003 21.0 8.9 6.8 7.1 0.6 5.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 KKK16654.1 - 0.0042 17.7 22.5 1.1 10.0 0.0 7.0 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_19 PF14559.6 KKK16654.1 - 0.0049 17.4 8.9 12 6.5 0.4 6.3 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.6 KKK16654.1 - 0.028 14.8 0.4 18 6.0 0.0 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.6 KKK16654.1 - 0.039 14.0 8.8 21 5.4 0.0 6.1 7 0 0 7 7 7 0 Tetratricopeptide repeat ABATE PF07336.11 KKK16654.1 - 0.053 14.2 2.5 0.2 12.3 0.3 3.1 3 0 0 3 3 3 0 Putative stress-induced transcription regulator DUF5444 PF17519.2 KKK16654.1 - 1.9 8.6 3.9 1.1 9.3 0.5 2.3 3 0 0 3 3 2 0 Family of unknown function (DUF5444) TPR_10 PF13374.6 KKK16654.1 - 4.3 7.3 10.6 2.5 8.1 0.0 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat NDUFA12 PF05071.16 KKK16655.1 - 4.4e-31 107.6 1.1 5.4e-31 107.3 1.1 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 PLDc_2 PF13091.6 KKK16656.1 - 1e-15 57.8 0.0 3.2e-09 36.8 0.0 2.2 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 KKK16656.1 - 1.5e-07 31.3 1.6 0.0053 16.9 0.4 3.2 2 1 0 2 2 2 2 Phospholipase D Active site motif DnaG_DnaB_bind PF08278.11 KKK16656.1 - 0.004 17.7 0.0 0.024 15.3 0.0 2.0 2 0 0 2 2 2 1 DNA primase DnaG DnaB-binding SNF2_N PF00176.23 KKK16657.1 - 6e-37 127.2 0.0 1.4e-35 122.7 0.0 2.3 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KKK16657.1 - 6.9e-18 65.0 0.0 1.7e-17 63.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KKK16657.1 - 0.00014 21.9 0.0 0.0011 19.1 0.0 2.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KKK16657.1 - 0.0002 20.7 0.0 0.00039 19.7 0.0 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Alpha-2-MRAP_C PF06401.11 KKK16657.1 - 0.00094 19.2 1.0 0.00094 19.2 1.0 2.5 3 0 0 3 3 3 1 Alpha-2-macroglobulin RAP, C-terminal domain HDA2-3 PF11496.8 KKK16657.1 - 0.0046 16.2 0.0 0.018 14.2 0.0 1.7 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 SWI2_SNF2 PF18766.1 KKK16657.1 - 0.0049 16.6 0.1 2.7 7.6 0.0 2.8 2 0 0 2 2 2 2 SWI2/SNF2 ATPase SAM_1 PF00536.30 KKK16657.1 - 0.011 16.2 0.1 0.035 14.6 0.1 1.9 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) AAA_34 PF13872.6 KKK16657.1 - 0.035 13.0 0.0 0.1 11.4 0.0 1.7 1 1 0 1 1 1 0 P-loop containing NTP hydrolase pore-1 SNF2_N PF00176.23 KKK16658.1 - 1.6e-68 231.0 0.0 2.5e-68 230.4 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.11 KKK16658.1 - 2.4e-19 69.0 0.0 6.2e-19 67.7 0.0 1.7 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.31 KKK16658.1 - 2.1e-13 50.6 0.0 6.2e-13 49.1 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.6 KKK16658.1 - 2.9e-10 39.8 8.5 6.8e-10 38.6 8.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KKK16658.1 - 7.1e-09 35.9 9.9 9.4e-09 35.5 8.0 2.1 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 KKK16658.1 - 5.1e-08 32.8 5.2 1.5e-07 31.3 5.2 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KKK16658.1 - 5.3e-08 32.6 8.3 5.3e-08 32.6 8.3 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KKK16658.1 - 1.1e-07 31.6 6.6 1.1e-07 31.6 6.6 2.5 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KKK16658.1 - 2.2e-07 31.0 5.1 6.7e-07 29.5 5.1 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-Nse PF11789.8 KKK16658.1 - 2.7e-07 30.3 7.7 3.2e-07 30.1 6.3 1.8 2 0 0 2 2 1 1 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.6 KKK16658.1 - 5.6e-07 29.6 8.4 7.6e-07 29.2 7.1 2.0 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 KKK16658.1 - 7e-06 25.9 6.2 1.7e-05 24.7 6.2 1.7 1 0 0 1 1 1 1 zinc-RING finger domain U-box PF04564.15 KKK16658.1 - 9.7e-06 25.7 0.1 5.6e-05 23.2 0.0 2.2 2 0 0 2 2 2 1 U-box domain zf-ANAPC11 PF12861.7 KKK16658.1 - 0.00014 21.9 0.5 0.0003 20.8 0.5 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 KKK16658.1 - 0.0037 17.0 1.8 0.018 14.8 1.8 2.3 1 0 0 1 1 1 1 RING-like zinc finger Prok-RING_4 PF14447.6 KKK16658.1 - 0.0042 16.9 6.3 0.0042 16.9 6.3 2.0 2 1 0 2 2 1 1 Prokaryotic RING finger family 4 SIMPL PF04402.14 KKK16658.1 - 0.097 13.1 1.6 3.2 8.2 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF541) DUF1644 PF07800.12 KKK16658.1 - 0.34 11.0 4.0 12 6.0 0.3 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1644) zf-RING_4 PF14570.6 KKK16658.1 - 0.83 9.5 6.1 4.1 7.3 6.4 2.0 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain Prok-RING_1 PF14446.6 KKK16658.1 - 0.96 9.4 4.1 21 5.1 0.1 2.4 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 zf-RING_10 PF16685.5 KKK16658.1 - 1.2 9.3 3.7 3.3 7.9 3.7 1.7 1 0 0 1 1 1 0 zinc RING finger of MSL2 MFS_1 PF07690.16 KKK16659.1 - 1.5e-43 149.1 43.8 1.5e-43 149.1 43.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KKK16659.1 - 2.5e-10 39.8 9.7 2.5e-10 39.8 9.7 2.5 1 1 2 3 3 3 1 Sugar (and other) transporter MBOAT_2 PF13813.6 KKK16660.1 - 1.3e-21 76.6 5.2 1.9e-21 76.1 4.4 1.7 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family GSH_synth_ATP PF03917.17 KKK16661.1 - 3.3e-119 398.0 0.0 2.8e-117 391.6 0.0 2.0 1 1 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 KKK16661.1 - 3.6e-30 104.5 0.0 7.9e-30 103.4 0.0 1.6 1 0 0 1 1 1 1 Eukaryotic glutathione synthase DUF1304 PF06993.12 KKK16681.1 - 0.062 13.3 0.5 0.062 13.3 0.5 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1304) WD40 PF00400.32 KKK16687.1 - 1.2e-42 143.0 31.0 3.6e-08 33.9 0.6 8.8 7 2 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKK16687.1 - 2.3e-14 53.4 3.6 0.0013 19.0 0.1 4.9 3 1 3 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KKK16687.1 - 5.8e-05 21.9 0.4 0.0037 16.0 0.2 3.3 3 0 0 3 3 3 1 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KKK16687.1 - 0.016 14.2 0.0 5.6 5.8 0.0 3.2 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein B-block_TFIIIC PF04182.12 KKK16688.1 - 7.7e-22 77.3 0.2 6.4e-21 74.3 0.0 2.5 3 0 0 3 3 3 1 B-block binding subunit of TFIIIC MarR_2 PF12802.7 KKK16688.1 - 0.029 14.3 1.6 0.21 11.5 0.0 3.1 3 0 0 3 3 3 0 MarR family DEC-1_N PF04625.13 KKK16689.1 - 0.13 11.3 8.2 0.18 10.7 8.2 1.3 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Methyltransf_PK PF05891.12 KKK16690.1 - 1e-68 231.1 0.0 1.2e-68 231.0 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_25 PF13649.6 KKK16690.1 - 1.5e-07 32.0 0.0 2.4e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KKK16690.1 - 1.2e-05 25.8 0.1 1.9e-05 25.2 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KKK16690.1 - 1.4e-05 25.0 0.0 2e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KKK16690.1 - 0.00069 20.3 0.0 0.0011 19.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain SET PF00856.28 KKK16692.1 - 1.7e-18 67.6 0.0 3.2e-18 66.7 0.0 1.5 1 0 0 1 1 1 1 SET domain adh_short PF00106.25 KKK16693.1 - 1.2e-25 90.2 0.0 1.2e-22 80.3 0.0 2.1 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KKK16693.1 - 1.6e-15 57.3 0.1 5.4e-15 55.6 0.0 1.7 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KKK16693.1 - 2.9e-08 33.9 0.0 4.1e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 KKK16693.1 - 0.0019 17.7 0.0 0.0029 17.1 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KKK16693.1 - 0.0071 15.8 0.0 0.02 14.4 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KKK16693.1 - 0.04 13.1 0.0 0.058 12.5 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Shikimate_DH PF01488.20 KKK16693.1 - 0.093 12.8 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF1508 PF07411.12 KKK16693.1 - 0.49 10.3 1.8 3.7 7.5 0.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1508) Pro-kuma_activ PF09286.11 KKK16697.1 - 8.7e-41 139.5 0.3 1.9e-40 138.4 0.3 1.6 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 KKK16697.1 - 0.00032 20.1 0.0 0.00055 19.3 0.0 1.3 1 0 0 1 1 1 1 Subtilase family Lyase_8_N PF08124.11 KKK16697.1 - 0.11 11.3 0.0 0.17 10.8 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide lyase family 8, N terminal alpha-helical domain Phytase-like PF13449.6 KKK16698.1 - 6.5e-39 134.6 0.0 1.4e-38 133.5 0.0 1.5 1 0 0 1 1 1 1 Esterase-like activity of phytase TBCC PF07986.12 KKK16699.1 - 1.1e-31 109.1 0.8 2e-31 108.2 0.8 1.5 1 0 0 1 1 1 1 Tubulin binding cofactor C TBCC_N PF16752.5 KKK16699.1 - 3.5e-08 33.9 0.2 5.6e-08 33.2 0.2 1.3 1 0 0 1 1 1 1 Tubulin-specific chaperone C N-terminal domain RTX PF02382.15 KKK16699.1 - 0.095 12.4 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 N-terminal domain in RTX protein Coatomer_WDAD PF04053.14 KKK16700.1 - 4.7e-148 493.9 0.0 1.2e-147 492.6 0.0 1.6 2 0 0 2 2 2 1 Coatomer WD associated region COPI_C PF06957.11 KKK16700.1 - 7e-108 361.0 0.0 1.1e-107 360.4 0.0 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.32 KKK16700.1 - 1.6e-36 123.7 15.6 2.5e-07 31.3 0.2 7.4 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKK16700.1 - 9.5e-08 32.2 0.2 0.43 10.9 0.0 5.4 3 1 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KKK16700.1 - 0.049 12.3 6.5 5.5 5.5 0.0 3.9 2 1 1 4 4 4 0 Nucleoporin Nup120/160 Clathrin PF00637.20 KKK16700.1 - 0.078 12.9 0.3 1.3 8.9 0.0 2.8 3 0 0 3 3 3 0 Region in Clathrin and VPS LysR_substrate PF03466.20 KKK16700.1 - 0.094 12.1 0.0 0.21 10.9 0.0 1.5 1 0 0 1 1 1 0 LysR substrate binding domain SOBP PF15279.6 KKK16702.1 - 3.7 8.1 13.6 5.9 7.4 13.6 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein Evr1_Alr PF04777.13 KKK16703.1 - 2.8e-28 98.3 1.4 5.4e-28 97.4 1.4 1.5 1 0 0 1 1 1 1 Erv1 / Alr family CSN8_PSD8_EIF3K PF10075.9 KKK16704.1 - 2.3e-19 69.8 0.0 4.5e-19 68.9 0.0 1.4 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family DUF4170 PF13773.6 KKK16705.1 - 0.22 11.7 0.0 0.59 10.3 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4170) Adaptin_N PF01602.20 KKK16706.1 - 7.7e-138 460.3 5.9 9.7e-138 460.0 5.9 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KKK16706.1 - 1.6e-64 216.9 1.6 5.4e-60 202.1 0.3 2.6 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KKK16706.1 - 8.5e-19 67.7 2.6 1.2e-06 28.8 0.0 6.3 1 1 5 6 6 6 5 HEAT repeats HEAT PF02985.22 KKK16706.1 - 1.9e-12 46.3 7.3 0.023 14.9 0.0 7.7 8 0 0 8 8 7 2 HEAT repeat HEAT_EZ PF13513.6 KKK16706.1 - 0.00022 21.6 1.2 0.64 10.6 0.0 5.6 6 1 1 7 7 7 1 HEAT-like repeat CLASP_N PF12348.8 KKK16706.1 - 0.00025 20.7 0.1 2 7.9 0.0 4.1 2 1 2 4 4 4 2 CLASP N terminal Arm PF00514.23 KKK16706.1 - 0.0016 18.4 1.2 11 6.3 0.0 5.4 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat RTP1_C1 PF10363.9 KKK16706.1 - 0.011 15.9 0.4 1.9 8.7 0.0 4.0 2 2 2 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 UNC45-central PF11701.8 KKK16706.1 - 0.12 12.3 0.8 0.4 10.6 0.1 2.3 3 1 0 3 3 3 0 Myosin-binding striated muscle assembly central CAAP1 PF15335.6 KKK16706.1 - 0.41 11.2 3.2 0.36 11.4 0.1 2.4 3 0 0 3 3 2 0 Caspase activity and apoptosis inhibitor 1 Ribosomal_60s PF00428.19 KKK16706.1 - 1.4 9.5 13.7 8.8 7.0 0.6 3.8 3 0 0 3 3 3 0 60s Acidic ribosomal protein ADH_N PF08240.12 KKK16707.1 - 1.1e-19 70.3 5.0 1.9e-19 69.5 5.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KKK16707.1 - 4.4e-17 62.3 0.0 7.2e-17 61.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KKK16707.1 - 9.1e-08 33.2 0.0 1.4e-07 32.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 KKK16707.1 - 0.004 16.6 0.0 0.0061 15.9 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 KKK16707.1 - 0.017 14.4 0.0 0.03 13.6 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DUF983 PF06170.12 KKK16707.1 - 0.34 11.3 0.1 0.34 11.3 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF983) Thr_synth_N PF14821.6 KKK16708.1 - 4.1e-30 103.8 0.0 2.6e-29 101.2 0.0 2.3 2 0 0 2 2 2 1 Threonine synthase N terminus PALP PF00291.25 KKK16708.1 - 1.6e-12 47.5 0.0 4.5e-12 46.0 0.0 1.8 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF1366 PF07104.11 KKK16708.1 - 0.15 11.7 0.0 2.7 7.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1366) Hexapep PF00132.24 KKK16709.1 - 4.8e-11 41.9 11.7 2.2e-05 24.0 3.1 5.1 3 1 1 4 4 4 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KKK16709.1 - 4.8e-06 26.2 3.5 9.3e-05 22.1 0.2 3.0 3 1 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase RXT2_N PF08595.11 KKK16720.1 - 1e-42 145.8 0.1 1e-42 145.8 0.1 2.4 2 0 0 2 2 2 1 RXT2-like, N-terminal Rhomboid PF01694.22 KKK16721.1 - 9.5e-26 90.6 9.4 9.6e-26 90.6 8.1 1.6 2 0 0 2 2 2 1 Rhomboid family DUF2157 PF09925.9 KKK16721.1 - 0.00051 19.8 3.1 0.0015 18.3 3.1 1.8 1 1 0 1 1 1 1 Predicted membrane protein (DUF2157) DUF3439 PF11921.8 KKK16722.1 - 0.0013 18.6 3.5 0.0022 17.9 3.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3439) ATG16 PF08614.11 KKK16722.1 - 0.023 14.9 1.9 0.023 14.9 1.9 1.8 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) ABC_tran_CTD PF16326.5 KKK16722.1 - 0.03 14.6 4.0 0.087 13.1 1.5 2.2 1 1 0 2 2 2 0 ABC transporter C-terminal domain Dicty_REP PF05086.12 KKK16722.1 - 0.055 11.5 5.1 0.09 10.7 5.1 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Striatin PF08232.12 KKK16722.1 - 0.097 13.3 4.2 0.24 12.0 3.9 1.8 1 1 1 2 2 2 0 Striatin family DUF641 PF04859.12 KKK16722.1 - 0.14 12.5 2.1 0.87 9.9 2.3 2.0 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) SSP160 PF06933.11 KKK16722.1 - 0.91 7.6 9.8 1.2 7.3 9.8 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Mob1_phocein PF03637.17 KKK16723.1 - 7.1e-51 172.6 0.7 5.8e-50 169.6 0.7 2.0 1 1 0 1 1 1 1 Mob1/phocein family Leo1 PF04004.13 KKK16724.1 - 4.9e-29 101.3 0.1 1.9e-28 99.4 0.1 1.9 1 1 0 1 1 1 1 Leo1-like protein Zn_clus PF00172.18 KKK16725.1 - 7.8e-09 35.5 8.5 2.3e-08 34.0 8.5 1.9 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain S36_mt PF10937.8 KKK16725.1 - 0.23 13.1 1.3 0.64 11.6 1.3 1.7 1 0 0 1 1 1 0 Ribosomal protein S36, mitochondrial BOP1NT PF08145.12 KKK16726.1 - 2e-105 352.4 6.8 2.8e-105 351.9 6.8 1.2 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.32 KKK16726.1 - 0.0028 18.5 0.1 0.7 10.9 0.0 3.8 4 0 0 4 4 4 1 WD domain, G-beta repeat PhoD PF09423.10 KKK16728.1 - 1.3e-09 37.5 0.3 2.6e-05 23.4 0.3 2.6 2 1 0 2 2 2 2 PhoD-like phosphatase Gryzun PF07919.12 KKK16729.1 - 6e-233 774.9 0.0 7.3e-233 774.6 0.0 1.1 1 0 0 1 1 1 1 Gryzun, putative trafficking through Golgi Foie-gras_1 PF11817.8 KKK16729.1 - 2.7e-100 335.2 6.1 7.1e-89 297.8 6.3 3.7 3 1 0 3 3 3 2 Foie gras liver health family 1 Glutaredoxin PF00462.24 KKK16730.1 - 5.8e-14 52.1 0.2 3.3e-13 49.6 0.0 2.2 2 0 0 2 2 2 1 Glutaredoxin TraF PF13728.6 KKK16730.1 - 0.052 13.4 0.0 0.094 12.5 0.0 1.5 1 0 0 1 1 1 0 F plasmid transfer operon protein Abhydrolase_1 PF00561.20 KKK16731.1 - 9.2e-09 35.3 0.0 2.3e-08 34.0 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KKK16731.1 - 2.1e-07 30.5 0.0 1e-06 28.2 0.0 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KKK16731.1 - 5e-07 30.5 2.2 2.5e-06 28.3 2.2 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Macoilin PF09726.9 KKK16731.1 - 6.2 5.2 9.4 13 4.2 9.4 1.6 1 0 0 1 1 1 0 Macoilin family DUF3336 PF11815.8 KKK16732.1 - 2.2e-35 121.3 0.0 4.9e-35 120.2 0.0 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3336) Patatin PF01734.22 KKK16732.1 - 4.5e-15 56.4 3.5 5.4e-15 56.1 0.7 2.1 2 0 0 2 2 2 1 Patatin-like phospholipase Ribosomal_L6 PF00347.23 KKK16733.1 - 2e-23 82.8 2.9 7.3e-11 42.6 1.0 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 Fungal_trans_2 PF11951.8 KKK16749.1 - 3e-05 23.0 0.4 0.00012 21.1 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain BPS PF08947.10 KKK16749.1 - 0.14 12.0 0.0 0.4 10.5 0.0 1.8 1 0 0 1 1 1 0 BPS (Between PH and SH2) SnoaL_2 PF12680.7 KKK16750.1 - 5.4e-06 27.0 0.0 6.6e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain MFS_1 PF07690.16 KKK16751.1 - 9.5e-27 93.8 31.3 9.5e-27 93.8 31.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily CAP_GLY PF01302.25 KKK16752.1 - 2.4e-15 56.3 0.8 5e-15 55.3 0.8 1.5 1 0 0 1 1 1 1 CAP-Gly domain CLIP1_ZNF PF16641.5 KKK16752.1 - 1.2e-10 41.0 9.4 4.9e-05 23.1 1.0 2.6 2 0 0 2 2 2 2 CLIP1 zinc knuckle TMF_DNA_bd PF12329.8 KKK16752.1 - 0.00016 21.6 25.4 0.34 10.9 3.7 5.1 5 0 0 5 5 5 2 TATA element modulatory factor 1 DNA binding FAM76 PF16046.5 KKK16752.1 - 0.0043 16.5 1.2 0.0043 16.5 1.2 3.2 1 1 2 3 3 3 1 FAM76 protein Seryl_tRNA_N PF02403.22 KKK16752.1 - 0.018 15.2 8.9 0.65 10.2 2.0 3.6 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain NPV_P10 PF05531.12 KKK16752.1 - 0.025 15.1 9.8 1.3 9.5 0.3 3.5 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein SKA1 PF07160.12 KKK16752.1 - 0.028 14.3 7.6 1.6 8.6 1.5 3.2 3 0 0 3 3 3 0 Spindle and kinetochore-associated protein 1 Phage_GP20 PF06810.11 KKK16752.1 - 0.028 14.2 19.7 0.15 11.8 1.4 3.9 4 0 0 4 4 4 0 Phage minor structural protein GP20 YajC PF02699.15 KKK16752.1 - 0.14 12.1 0.9 0.37 10.7 0.1 2.1 2 0 0 2 2 2 0 Preprotein translocase subunit SHE3 PF17078.5 KKK16752.1 - 0.14 11.9 9.3 4.2 7.0 0.0 2.5 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 BLOC1_2 PF10046.9 KKK16752.1 - 0.17 12.2 17.1 0.14 12.5 2.9 3.9 4 0 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Spc29 PF17082.5 KKK16752.1 - 0.36 10.6 8.8 4.4 7.1 0.1 3.3 2 1 1 3 3 3 0 Spindle Pole Component 29 End3 PF12761.7 KKK16752.1 - 0.38 10.9 13.4 4.9 7.3 0.1 3.3 3 0 0 3 3 3 0 Actin cytoskeleton-regulatory complex protein END3 Med28 PF11594.8 KKK16752.1 - 0.48 10.5 3.1 1.2 9.2 0.1 2.7 2 1 1 3 3 3 0 Mediator complex subunit 28 EzrA PF06160.12 KKK16752.1 - 0.74 7.9 21.5 0.035 12.3 14.5 2.1 2 1 0 2 2 2 0 Septation ring formation regulator, EzrA V_ATPase_I PF01496.19 KKK16752.1 - 1.4 6.7 7.4 21 2.9 6.4 2.1 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Fez1 PF06818.15 KKK16752.1 - 2.1 8.8 31.8 63 3.9 2.2 3.4 1 1 0 2 2 2 0 Fez1 zf_PR_Knuckle PF18445.1 KKK16752.1 - 2.1 8.2 4.8 3 7.7 0.4 2.3 2 0 0 2 2 2 0 PR zinc knuckle motif HemX PF04375.14 KKK16752.1 - 3.7 6.8 18.5 0.62 9.3 3.5 3.1 2 1 0 3 3 3 0 HemX, putative uroporphyrinogen-III C-methyltransferase DUF812 PF05667.11 KKK16752.1 - 4.2 6.2 23.1 0.033 13.1 12.2 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF812) AAA_13 PF13166.6 KKK16752.1 - 4.3 5.8 15.6 0.51 8.9 7.6 2.2 1 1 1 3 3 3 0 AAA domain TPR_MLP1_2 PF07926.12 KKK16752.1 - 4.5 7.4 31.7 0.11 12.6 11.0 3.3 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein DUF241 PF03087.14 KKK16752.1 - 5.7 6.7 9.7 1.6 8.5 5.6 2.2 2 1 0 2 2 2 0 Arabidopsis protein of unknown function Spc7 PF08317.11 KKK16752.1 - 5.9 5.7 30.6 2.8 6.8 9.5 3.1 1 1 2 3 3 3 0 Spc7 kinetochore protein DUF1664 PF07889.12 KKK16752.1 - 6 6.9 14.5 3.3 7.8 3.0 3.4 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) DUF4407 PF14362.6 KKK16752.1 - 8.4 5.6 16.6 27 4.0 12.3 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Pkinase PF00069.25 KKK16753.1 - 1.6e-33 116.2 0.0 8.3e-20 71.2 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KKK16753.1 - 2.1e-13 50.2 0.0 3e-12 46.4 0.0 2.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KKK16753.1 - 0.0019 17.6 0.0 0.58 9.4 0.0 2.3 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 KKK16753.1 - 0.026 14.5 0.0 0.053 13.4 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family BTB PF00651.31 KKK16754.1 - 0.16 12.2 0.3 12 6.2 0.0 2.7 3 0 0 3 3 3 0 BTB/POZ domain Neisseria_TspB PF05616.13 KKK16754.1 - 2.1 6.7 10.5 3.5 6.0 10.5 1.2 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein SLAC1 PF03595.17 KKK16755.1 - 8.1e-67 225.8 30.6 1.1e-44 153.1 19.0 2.0 1 1 1 2 2 2 2 Voltage-dependent anion channel RTC_insert PF05189.13 KKK16756.1 - 3.6e-29 101.3 0.0 7.1e-29 100.4 0.0 1.5 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain RTC PF01137.21 KKK16756.1 - 4.9e-26 91.3 0.0 6e-26 91.0 0.0 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase 3-HAO PF06052.12 KKK16757.1 - 3.4e-44 150.1 0.0 5e-44 149.6 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.11 KKK16757.1 - 0.00059 19.5 0.0 0.00097 18.8 0.0 1.4 1 0 0 1 1 1 1 Cupin domain DZR PF12773.7 KKK16757.1 - 0.00069 19.6 0.9 0.0013 18.7 0.9 1.4 1 0 0 1 1 1 1 Double zinc ribbon Cupin_1 PF00190.22 KKK16757.1 - 0.014 15.0 0.1 0.022 14.4 0.0 1.4 2 0 0 2 2 2 0 Cupin Nudix_N_2 PF14803.6 KKK16757.1 - 0.017 15.0 1.2 3.5 7.6 0.1 2.5 2 0 0 2 2 2 0 Nudix N-terminal Plant_tran PF04827.14 KKK16757.1 - 0.039 13.5 0.1 0.05 13.2 0.1 1.3 1 0 0 1 1 1 0 Plant transposon protein zf-RRN7 PF11781.8 KKK16757.1 - 0.13 12.0 5.5 4.2 7.2 0.3 2.9 3 0 0 3 3 3 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 ADK_lid PF05191.14 KKK16757.1 - 0.56 10.2 4.0 9.2 6.3 0.1 2.6 2 0 0 2 2 2 0 Adenylate kinase, active site lid Zn-ribbon_8 PF09723.10 KKK16757.1 - 0.7 10.1 5.8 4.3 7.5 3.2 2.8 2 1 1 3 3 3 0 Zinc ribbon domain TF_Zn_Ribbon PF08271.12 KKK16757.1 - 0.83 9.2 4.4 2.8 7.5 0.3 2.9 1 1 2 3 3 2 0 TFIIB zinc-binding DUF35_N PF12172.8 KKK16757.1 - 7.1 6.6 8.9 5.6 7.0 0.1 2.9 3 0 0 3 3 3 0 Rubredoxin-like zinc ribbon domain (DUF35_N) SpoIIE PF07228.12 KKK16758.1 - 3.5e-11 43.4 0.2 7.6e-10 39.0 0.1 2.1 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.21 KKK16758.1 - 2.9e-07 30.4 0.0 0.013 15.2 0.0 2.3 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 KKK16758.1 - 1.4e-06 28.1 1.0 3.3e-06 26.9 1.0 1.6 1 1 0 1 1 1 1 Protein phosphatase 2C WD40 PF00400.32 KKK16759.1 - 2.8e-35 119.7 21.8 5.5e-07 30.2 2.6 7.5 7 1 0 7 7 7 6 WD domain, G-beta repeat PRP4 PF08799.11 KKK16759.1 - 1.1e-15 56.8 5.1 2e-15 56.0 5.1 1.5 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like ANAPC4_WD40 PF12894.7 KKK16759.1 - 7e-11 42.3 0.1 0.015 15.5 0.0 5.2 3 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KKK16759.1 - 0.023 14.0 0.0 0.11 11.8 0.0 2.1 3 0 0 3 3 3 0 WD40-like domain Ge1_WD40 PF16529.5 KKK16759.1 - 0.045 12.7 0.0 5.6 5.8 0.0 3.1 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Nop53 PF07767.11 KKK16759.1 - 0.11 11.8 6.5 0.17 11.3 6.5 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) PRTP PF01366.18 KKK16759.1 - 0.28 9.2 0.8 0.39 8.7 0.8 1.1 1 0 0 1 1 1 0 Herpesvirus processing and transport protein HSCB_C PF07743.13 KKK16760.1 - 6e-21 74.7 0.0 1.5e-19 70.2 0.0 2.1 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.31 KKK16760.1 - 1.9e-05 24.7 0.1 3.7e-05 23.8 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain Med21 PF11221.8 KKK16760.1 - 5.3 7.3 5.1 4.9 7.4 2.6 2.0 1 1 1 2 2 2 0 Subunit 21 of Mediator complex Glyco_hydro_43 PF04616.14 KKK16761.1 - 4.4e-29 101.7 4.9 1e-28 100.5 4.9 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 P_proprotein PF01483.20 KKK16761.1 - 0.0079 16.2 0.2 0.088 12.8 0.1 2.3 2 0 0 2 2 2 1 Proprotein convertase P-domain Zn_clus PF00172.18 KKK16788.1 - 0.0012 18.9 6.0 0.0019 18.3 6.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AT_hook PF02178.19 KKK16788.1 - 0.1 12.5 6.8 0.33 11.0 6.8 1.9 1 0 0 1 1 1 0 AT hook motif DUF1746 PF08508.10 KKK16812.1 - 3.6e-41 140.1 1.3 5.4e-41 139.5 1.3 1.3 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1746) DUF4834 PF16118.5 KKK16812.1 - 1.6 9.8 3.5 28 5.7 3.6 2.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) Peptidase_M18 PF02127.15 KKK16813.1 - 1.7e-163 544.4 0.0 1.9e-163 544.2 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) CcmD PF04995.14 KKK16814.1 - 0.86 9.7 3.2 0.76 9.9 1.2 1.9 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) SMC_N PF02463.19 KKK16815.1 - 7.2e-60 202.2 0.0 1.6e-58 197.7 0.0 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KKK16815.1 - 1.2e-30 106.2 1.6 2.3e-30 105.3 0.0 2.3 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 KKK16815.1 - 6.3e-12 45.9 9.6 2.9e-06 27.3 0.4 3.5 3 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KKK16815.1 - 3.7e-08 33.0 0.0 7.7e-08 32.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 KKK16815.1 - 2.3e-07 30.9 5.8 2.3e-07 30.9 5.8 4.4 3 1 1 4 4 3 1 AAA ATPase domain SbcCD_C PF13558.6 KKK16815.1 - 0.003 17.7 0.1 0.042 14.1 0.0 3.0 3 0 0 3 3 3 1 Putative exonuclease SbcCD, C subunit DUF1664 PF07889.12 KKK16815.1 - 0.0041 17.1 3.5 0.0041 17.1 3.5 7.8 5 1 4 9 9 9 1 Protein of unknown function (DUF1664) DUF948 PF06103.11 KKK16815.1 - 0.01 16.1 26.7 0.37 11.1 1.6 6.9 5 2 1 6 6 6 2 Bacterial protein of unknown function (DUF948) AAA_23 PF13476.6 KKK16815.1 - 0.02 15.4 105.0 0.55 10.7 1.7 6.6 3 2 1 4 4 2 0 AAA domain AAA_22 PF13401.6 KKK16815.1 - 1.9 8.8 11.0 10 6.4 0.0 5.3 5 1 0 5 5 5 0 AAA domain Mce4_CUP1 PF11887.8 KKK16815.1 - 3.7 6.9 6.0 1.8 7.9 0.3 2.7 3 0 0 3 3 3 0 Cholesterol uptake porter CUP1 of Mce4, putative WD40 PF00400.32 KKK16816.1 - 1.5e-24 85.8 11.5 0.00021 22.0 0.1 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKK16816.1 - 1.4e-12 47.8 4.4 0.0014 18.9 0.3 4.5 4 1 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KKK16816.1 - 1.7e-07 31.3 0.1 0.017 15.0 0.0 3.2 2 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KKK16816.1 - 0.053 12.5 0.0 0.11 11.4 0.0 1.6 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PALB2_WD40 PF16756.5 KKK16816.1 - 0.13 11.1 1.3 4.5 6.1 0.1 2.3 2 0 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain E3_binding PF02817.17 KKK16817.1 - 7.3e-10 39.0 0.1 7.5e-08 32.6 0.0 2.8 2 0 0 2 2 2 2 e3 binding domain MRP_L53 PF10780.9 KKK16819.1 - 2.7e-18 65.9 0.1 3.9e-18 65.4 0.1 1.2 1 0 0 1 1 1 1 39S ribosomal protein L53/MRP-L53 Pyrophosphatase PF00719.19 KKK16820.1 - 2.5e-58 196.4 0.1 3.4e-58 196.0 0.1 1.2 1 0 0 1 1 1 1 Inorganic pyrophosphatase Dus PF01207.17 KKK16821.1 - 2.4e-44 151.7 0.1 8.6e-44 149.9 0.1 1.7 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) HisKA_4TM PF16926.5 KKK16821.1 - 0.13 11.8 0.7 1.2 8.7 0.0 2.2 2 0 0 2 2 2 0 Archaeal 4TM region of histidine kinase PrmA PF06325.13 KKK16821.1 - 0.15 11.4 0.0 0.33 10.3 0.0 1.5 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) Glyco_transf_8 PF01501.20 KKK16822.1 - 3.3e-07 30.1 0.0 4.4e-07 29.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 8 Nucleotid_trans PF03407.16 KKK16822.1 - 0.15 12.0 0.0 0.18 11.7 0.0 1.1 1 0 0 1 1 1 0 Nucleotide-diphospho-sugar transferase MHYT PF03707.16 KKK16861.1 - 2.1e-19 69.4 23.3 5.2e-09 36.1 1.9 4.5 4 0 0 4 4 4 4 Bacterial signalling protein N terminal repeat OTU PF02338.19 KKK16862.1 - 5e-08 33.5 0.0 1.7e-07 31.7 0.0 1.8 1 1 0 1 1 1 1 OTU-like cysteine protease CUE PF02845.16 KKK16862.1 - 0.016 14.9 0.0 0.049 13.3 0.0 1.8 1 0 0 1 1 1 0 CUE domain STIL_N PF15253.6 KKK16862.1 - 0.15 11.0 0.6 0.24 10.3 0.6 1.2 1 0 0 1 1 1 0 SCL-interrupting locus protein N-terminus Amidohydro_1 PF01979.20 KKK16863.1 - 2.8e-64 217.6 0.0 3.3e-64 217.4 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KKK16863.1 - 1.2e-14 54.6 0.0 6.4e-12 45.7 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family A_deaminase PF00962.22 KKK16863.1 - 0.0022 17.4 0.0 0.0041 16.5 0.0 1.5 1 0 0 1 1 1 1 Adenosine/AMP deaminase RHH_1 PF01402.21 KKK16863.1 - 0.12 12.3 0.2 20 5.3 0.0 2.6 2 0 0 2 2 2 0 Ribbon-helix-helix protein, copG family COPI_assoc PF08507.10 KKK16864.1 - 1.2e-31 109.5 8.3 1.4e-31 109.3 8.3 1.0 1 0 0 1 1 1 1 COPI associated protein Cg6151-P PF10233.9 KKK16864.1 - 0.15 12.4 8.8 0.26 11.6 8.4 1.6 1 1 0 1 1 1 0 Uncharacterized conserved protein CG6151-P UCR_Fe-S_N PF10399.9 KKK16864.1 - 0.19 11.1 0.9 0.35 10.3 0.0 1.8 2 0 0 2 2 2 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal MFS_MOT1 PF16983.5 KKK16864.1 - 3.2 8.2 9.2 57 4.2 9.2 2.6 1 1 0 1 1 1 0 Molybdate transporter of MFS superfamily ALMT PF11744.8 KKK16864.1 - 3.7 6.3 4.7 4.6 6.0 4.7 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter SdpI PF13630.6 KKK16864.1 - 6.4 7.0 12.6 0.51 10.5 5.2 2.1 2 0 0 2 2 2 0 SdpI/YhfL protein family DAO PF01266.24 KKK16865.1 - 3.1e-36 125.7 0.1 3.6e-36 125.5 0.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KKK16865.1 - 0.00038 20.6 0.0 0.0011 19.2 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KKK16865.1 - 0.00055 19.3 1.5 0.00084 18.6 0.0 2.1 2 0 0 2 2 2 1 Thi4 family DUF3889 PF13028.6 KKK16865.1 - 0.044 13.7 0.2 0.075 13.0 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3889) adh_short PF00106.25 KKK16866.1 - 7.5e-54 182.2 0.1 1e-53 181.7 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KKK16866.1 - 3.6e-37 128.2 0.0 4.9e-37 127.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KKK16866.1 - 7.8e-13 48.7 0.0 1.2e-12 48.2 0.0 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KKK16866.1 - 0.001 18.3 0.1 0.0023 17.1 0.1 1.7 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein DUF1776 PF08643.10 KKK16866.1 - 0.0092 15.4 0.0 0.016 14.6 0.0 1.3 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Sacchrp_dh_NADP PF03435.18 KKK16866.1 - 0.02 15.1 0.1 0.045 14.0 0.1 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 KKK16866.1 - 0.027 13.9 0.1 0.063 12.7 0.1 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family GATA PF00320.27 KKK16867.1 - 2.7e-28 97.3 17.3 1.4e-14 53.4 6.0 2.5 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.12 KKK16867.1 - 1.1e-05 24.8 3.7 0.0066 15.9 0.1 2.4 2 0 0 2 2 2 2 TFIIB zinc-binding Zn-ribbon_8 PF09723.10 KKK16867.1 - 0.0002 21.4 2.7 0.11 12.7 0.3 2.6 2 0 0 2 2 2 2 Zinc ribbon domain OrfB_Zn_ribbon PF07282.11 KKK16867.1 - 0.0011 18.8 4.4 0.077 12.9 0.5 2.6 2 0 0 2 2 2 2 Putative transposase DNA-binding domain Auto_anti-p27 PF06677.12 KKK16867.1 - 0.0014 18.7 5.4 0.05 13.8 0.4 2.4 2 0 0 2 2 2 2 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) eIF-5_eIF-2B PF01873.17 KKK16867.1 - 0.02 14.8 3.7 2.5 8.0 0.4 2.4 2 0 0 2 2 2 0 Domain found in IF2B/IF5 DZR PF12773.7 KKK16867.1 - 0.041 13.9 10.3 27 4.9 10.3 3.0 1 1 0 1 1 1 0 Double zinc ribbon ArfGap PF01412.18 KKK16867.1 - 0.12 12.5 3.6 0.66 10.1 0.2 2.3 2 0 0 2 2 2 0 Putative GTPase activating protein for Arf Neisseria_TspB PF05616.13 KKK16867.1 - 1.6 7.1 6.2 0.47 8.9 0.5 2.1 2 0 0 2 2 2 0 Neisseria meningitidis TspB protein Rubredoxin_2 PF18073.1 KKK16867.1 - 4.4 7.1 10.6 18 5.1 0.2 4.4 4 0 0 4 4 4 0 Rubredoxin metal binding domain Ribonuc_L-PSP PF01042.21 KKK16869.1 - 1.7e-32 112.0 0.0 2e-32 111.8 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP Fe-ADH PF00465.19 KKK16869.1 - 0.0018 17.2 0.0 0.0022 16.9 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Cation_efflux PF01545.21 KKK16870.1 - 1.7e-53 181.3 2.6 2.2e-53 181.0 2.6 1.1 1 0 0 1 1 1 1 Cation efflux family BPD_transp_2 PF02653.16 KKK16870.1 - 0.014 14.5 0.5 0.014 14.5 0.5 2.0 2 1 0 2 2 2 0 Branched-chain amino acid transport system / permease component PAP2_3 PF14378.6 KKK16870.1 - 0.093 12.4 4.5 0.68 9.6 0.1 2.3 2 0 0 2 2 2 0 PAP2 superfamily TMEM43 PF07787.12 KKK16870.1 - 2.3 7.6 4.6 4.5 6.6 0.3 2.2 2 0 0 2 2 2 0 Transmembrane protein 43 SH3_1 PF00018.28 KKK16871.1 - 1.6e-25 88.5 0.0 2.5e-11 43.0 0.0 2.9 3 0 0 3 3 3 2 SH3 domain SH3_9 PF14604.6 KKK16871.1 - 7.2e-14 51.4 0.1 4.3e-06 26.5 0.1 2.6 2 0 0 2 2 2 2 Variant SH3 domain PX PF00787.24 KKK16871.1 - 4.4e-13 49.2 0.0 1.2e-12 47.8 0.0 1.7 2 0 0 2 2 2 1 PX domain SH3_2 PF07653.17 KKK16871.1 - 7e-09 35.2 0.0 4.7e-05 23.0 0.0 3.2 3 0 0 3 3 3 2 Variant SH3 domain PB1 PF00564.24 KKK16871.1 - 8.3e-08 32.1 0.5 1.7e-07 31.1 0.5 1.5 1 0 0 1 1 1 1 PB1 domain AFG1_ATPase PF03969.16 KKK16872.1 - 1.2e-94 317.3 0.0 6.5e-90 301.6 0.0 2.1 2 0 0 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.6 KKK16872.1 - 0.00054 20.4 0.2 0.63 10.4 0.0 3.1 3 1 0 4 4 4 2 AAA ATPase domain AAA_14 PF13173.6 KKK16872.1 - 0.0018 18.3 0.0 0.0035 17.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 KKK16872.1 - 0.008 16.6 0.0 0.021 15.2 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KKK16872.1 - 0.018 15.3 0.0 0.053 13.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 KKK16872.1 - 0.022 14.7 0.0 0.042 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 KKK16872.1 - 0.041 14.3 0.0 0.17 12.3 0.0 2.2 1 0 0 1 1 1 0 RNA helicase Bac_DnaA PF00308.18 KKK16872.1 - 0.043 13.7 0.1 4.3 7.1 0.1 2.4 2 1 0 2 2 2 0 Bacterial dnaA protein TsaE PF02367.17 KKK16872.1 - 0.17 11.9 0.0 0.3 11.1 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE MTP18 PF10558.9 KKK16873.1 - 1.8e-82 275.4 0.1 2.8e-82 274.8 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) Uricase PF01014.18 KKK16894.1 - 1e-77 258.7 2.1 7.4e-41 139.5 0.4 2.0 2 0 0 2 2 2 2 Uricase Mob_Pre PF01076.19 KKK16894.1 - 0.076 12.8 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Plasmid recombination enzyme Inv-AAD PF18785.1 KKK16895.1 - 1.9e-45 153.9 0.0 2.6e-45 153.4 0.0 1.1 1 0 0 1 1 1 1 Invertebrate-AID/APOBEC-deaminase dCMP_cyt_deam_1 PF00383.23 KKK16895.1 - 9.1e-12 44.7 0.0 4.8e-11 42.4 0.0 2.0 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region APOBEC_N PF08210.11 KKK16895.1 - 9.9e-05 22.3 0.0 0.00016 21.6 0.0 1.4 1 1 0 1 1 1 1 APOBEC-like N-terminal domain SNAD4 PF18750.1 KKK16895.1 - 0.0097 16.0 0.0 0.017 15.3 0.0 1.3 1 0 0 1 1 1 1 Secreted Novel AID/APOBEC-like Deaminase 4 Bd3614-deam PF14439.6 KKK16895.1 - 0.07 13.2 0.1 0.32 11.1 0.0 2.1 1 1 1 2 2 2 0 Bd3614-like deaminase zf-H2C2_2 PF13465.6 KKK16896.1 - 5.4e-06 26.6 12.1 1.6e-05 25.1 1.4 2.9 3 0 0 3 3 3 2 Zinc-finger double domain zf-Di19 PF05605.12 KKK16896.1 - 0.00022 21.4 4.7 0.00039 20.6 4.7 1.3 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 KKK16896.1 - 0.00026 21.6 15.0 0.017 15.9 5.6 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KKK16896.1 - 0.0019 18.4 4.8 0.078 13.3 1.2 2.3 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 KKK16896.1 - 0.034 14.6 14.5 0.11 12.9 7.1 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-met PF12874.7 KKK16896.1 - 0.75 10.3 5.0 4.2 7.9 0.8 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Trp_oprn_chp PF09534.10 KKK16901.1 - 0.25 11.1 3.1 4.3 7.1 0.2 2.1 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Zn_clus PF00172.18 KKK16903.1 - 2.3e-08 34.0 6.1 2.3e-08 34.0 6.1 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Hydrophobin PF01185.18 KKK16904.1 - 2.2e-08 34.6 7.2 3e-08 34.2 7.2 1.2 1 0 0 1 1 1 1 Fungal hydrophobin SRR1 PF07985.12 KKK16904.1 - 0.088 12.9 0.6 0.25 11.4 0.0 1.8 2 0 0 2 2 2 0 SRR1 Acetyltransf_1 PF00583.25 KKK16905.1 - 5e-09 36.4 0.0 8.2e-09 35.7 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KKK16905.1 - 1.1e-08 35.4 0.0 1.6e-07 31.6 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KKK16905.1 - 1.5e-07 31.4 0.0 7e-07 29.2 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KKK16905.1 - 0.00017 21.6 0.0 0.013 15.6 0.0 2.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KKK16905.1 - 0.00028 20.8 0.0 0.00056 19.8 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 KKK16905.1 - 0.0012 19.0 0.0 0.0025 17.9 0.0 1.6 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase PanZ PF12568.8 KKK16905.1 - 0.0025 17.6 0.0 0.0066 16.2 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain, PanZ Zip PF02535.22 KKK16906.1 - 2.5e-37 128.8 10.7 2.5e-37 128.8 10.7 1.8 2 0 0 2 2 2 1 ZIP Zinc transporter Thyroglobulin_1 PF00086.18 KKK16906.1 - 0.016 14.9 0.4 6.8 6.4 0.1 2.4 2 0 0 2 2 2 0 Thyroglobulin type-1 repeat Myco_arth_vir_N PF09610.10 KKK16907.1 - 1.8 8.7 4.4 2.7 8.1 4.4 1.4 1 0 0 1 1 1 0 Mycoplasma virulence signal region (Myco_arth_vir_N) p450 PF00067.22 KKK16908.1 - 1e-58 199.2 0.0 1.5e-58 198.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_10 PF00331.20 KKK16909.1 - 3.5e-99 331.9 1.4 2.3e-78 263.5 0.5 2.0 1 1 1 2 2 2 2 Glycosyl hydrolase family 10 NmrA PF05368.13 KKK16910.1 - 1.3e-38 132.9 0.0 1.6e-38 132.6 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KKK16910.1 - 3.5e-23 82.4 0.0 4.7e-23 82.0 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KKK16910.1 - 4e-05 23.2 0.0 0.00018 21.1 0.0 2.0 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KKK16910.1 - 0.02 13.9 0.0 0.051 12.6 0.0 1.6 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 KKK16910.1 - 0.022 14.2 0.0 0.04 13.4 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase TrkA_N PF02254.18 KKK16910.1 - 0.1 12.9 0.0 0.19 12.0 0.0 1.5 1 1 0 1 1 1 0 TrkA-N domain SHR3_chaperone PF08229.11 KKK16911.1 - 3.4e-74 247.9 0.0 3.7e-74 247.8 0.0 1.0 1 0 0 1 1 1 1 ER membrane protein SH3 DUF5453 PF17534.2 KKK16911.1 - 0.055 13.4 0.2 0.11 12.5 0.0 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5453) PHR PF08005.12 KKK16911.1 - 0.059 14.0 0.0 0.078 13.7 0.0 1.1 1 0 0 1 1 1 0 PHR domain PARG_cat PF05028.14 KKK16912.1 - 2.8e-44 151.8 0.0 3.8e-44 151.4 0.0 1.1 1 0 0 1 1 1 1 Poly (ADP-ribose) glycohydrolase (PARG) Response_reg PF00072.24 KKK16913.1 - 7.7e-21 74.4 0.0 1e-20 73.9 0.0 1.2 1 0 0 1 1 1 1 Response regulator receiver domain Arrestin_N PF00339.29 KKK16914.1 - 2.3e-13 50.4 0.0 7.8e-13 48.7 0.0 1.9 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 KKK16914.1 - 1.7e-09 38.2 0.0 1.2e-06 29.0 0.0 2.5 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Sugar_tr PF00083.24 KKK16915.1 - 1.1e-89 301.3 24.5 1.4e-89 301.0 24.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKK16915.1 - 2.2e-27 95.9 20.7 3e-27 95.5 17.8 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KKK16915.1 - 4.6e-05 22.0 4.2 4.6e-05 22.0 4.2 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) AA_permease_2 PF13520.6 KKK16917.1 - 1.9e-67 228.0 46.3 2.1e-67 227.8 46.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KKK16917.1 - 8.5e-27 93.9 38.7 1e-26 93.6 38.7 1.0 1 0 0 1 1 1 1 Amino acid permease SLATT_fungal PF18142.1 KKK16917.1 - 4.2 7.4 5.9 1.4 9.0 1.0 2.3 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain His_Phos_2 PF00328.22 KKK16918.1 - 2.5e-39 135.7 0.0 2.9e-39 135.5 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) bZIP_1 PF00170.21 KKK16920.1 - 6.4e-06 26.2 8.5 9.7e-06 25.6 8.5 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KKK16920.1 - 7e-06 26.0 10.6 1.2e-05 25.3 10.6 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 KKK16920.1 - 0.0018 18.8 6.5 0.0032 18.0 6.5 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor MCC-bdg_PDZ PF10506.9 KKK16920.1 - 0.022 14.8 0.5 0.035 14.1 0.5 1.3 1 0 0 1 1 1 0 PDZ domain of MCC-2 bdg protein for Usher syndrome CASP_C PF08172.12 KKK16920.1 - 0.028 13.8 3.7 0.042 13.2 3.7 1.2 1 0 0 1 1 1 0 CASP C terminal Macoilin PF09726.9 KKK16920.1 - 0.034 12.7 2.1 0.043 12.4 2.1 1.1 1 0 0 1 1 1 0 Macoilin family DivIC PF04977.15 KKK16920.1 - 0.07 12.9 2.4 0.1 12.4 2.4 1.2 1 0 0 1 1 1 0 Septum formation initiator HALZ PF02183.18 KKK16920.1 - 0.072 13.3 0.7 0.13 12.5 0.7 1.4 1 0 0 1 1 1 0 Homeobox associated leucine zipper Nsp1_C PF05064.13 KKK16920.1 - 0.098 12.5 0.5 0.15 11.9 0.5 1.3 1 0 0 1 1 1 0 Nsp1-like C-terminal region Takusan PF04822.13 KKK16920.1 - 0.43 10.5 4.0 0.49 10.3 2.8 1.7 1 1 0 1 1 1 0 Takusan ATG16 PF08614.11 KKK16920.1 - 0.68 10.1 10.9 1.4 9.1 10.9 1.6 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) Abhydrolase_3 PF07859.13 KKK16921.1 - 2.5e-45 154.9 2.7 3.9e-44 151.0 2.7 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KKK16921.1 - 3.9e-08 32.6 0.9 1.6e-07 30.6 0.9 1.7 1 1 0 1 1 1 1 Carboxylesterase family Esterase_phd PF10503.9 KKK16921.1 - 0.029 13.9 1.2 0.13 11.7 0.5 2.0 2 0 0 2 2 2 0 Esterase PHB depolymerase Abhydrolase_2 PF02230.16 KKK16921.1 - 0.062 13.1 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Esterase PF00756.20 KKK16921.1 - 0.1 12.2 0.0 0.26 10.9 0.0 1.6 1 1 0 1 1 1 0 Putative esterase PHO4 PF01384.20 KKK16934.1 - 4.6e-103 344.8 19.2 5.3e-103 344.6 19.2 1.0 1 0 0 1 1 1 1 Phosphate transporter family UPF0444 PF15475.6 KKK16934.1 - 0.77 10.1 7.9 1.3 9.3 0.7 2.8 2 0 0 2 2 2 0 Transmembrane protein C12orf23, UPF0444 MFS_1 PF07690.16 KKK16935.1 - 7.1e-21 74.5 62.7 1.7e-19 70.0 29.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily F-box PF00646.33 KKK16936.1 - 0.0042 16.9 0.4 14 5.7 0.0 3.6 3 0 0 3 3 3 1 F-box domain F-box-like PF12937.7 KKK16936.1 - 0.0052 16.7 10.0 0.1 12.5 6.6 3.5 3 1 0 3 3 3 1 F-box-like Adeno_PV PF03910.13 KKK16936.1 - 0.0078 15.0 0.4 0.013 14.3 0.4 1.2 1 0 0 1 1 1 1 Adenovirus minor core protein PV Cytokin_check_N PF10407.9 KKK16936.1 - 0.046 13.7 0.4 0.16 12.0 0.0 2.0 2 0 0 2 2 2 0 Cdc14 phosphatase binding protein N-terminus Glyco_transf_11 PF01531.16 KKK16936.1 - 0.19 10.9 0.0 0.33 10.1 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 11 Romo1 PF10247.9 KKK16937.1 - 0.052 13.9 0.3 1.6 9.1 0.1 2.3 2 0 0 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 ThrE PF06738.12 KKK16938.1 - 2.6e-70 236.5 12.7 2.8e-65 220.0 2.7 2.3 2 0 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 KKK16938.1 - 1.7e-13 50.9 7.1 1.7e-13 50.9 7.1 2.5 2 0 0 2 2 2 1 Threonine/Serine exporter, ThrE Fungal_trans_2 PF11951.8 KKK16940.1 - 8.8e-11 41.2 0.0 3.4e-10 39.3 0.0 1.5 1 1 1 2 2 2 1 Fungal specific transcription factor domain TFIIS_C PF01096.18 KKK16941.1 - 1.8 8.5 5.5 0.17 11.8 0.5 1.9 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) Cellulase PF00150.18 KKK16942.1 - 1.4e-16 60.8 0.3 3.1e-16 59.6 0.3 1.5 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF1100 PF06500.11 KKK16944.1 - 5.6e-10 38.6 0.0 7.7e-10 38.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Peptidase_S9 PF00326.21 KKK16944.1 - 3.2e-06 26.8 0.0 8.1e-06 25.4 0.0 1.6 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 KKK16944.1 - 0.00012 21.8 0.0 0.0002 21.0 0.0 1.4 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_1 PF00561.20 KKK16944.1 - 0.00022 21.0 0.1 0.00053 19.7 0.1 1.5 1 1 1 2 2 2 1 alpha/beta hydrolase fold BAAT_C PF08840.11 KKK16944.1 - 0.00047 20.1 0.0 0.0025 17.8 0.0 1.9 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Hydrolase_4 PF12146.8 KKK16944.1 - 0.0097 15.2 0.1 0.018 14.3 0.1 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KKK16944.1 - 0.011 16.4 2.4 0.017 15.7 1.7 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family Esterase PF00756.20 KKK16944.1 - 0.033 13.8 0.1 0.13 11.9 0.1 2.0 1 1 0 1 1 1 0 Putative esterase Esterase_phd PF10503.9 KKK16944.1 - 0.12 11.8 0.1 0.22 11.0 0.1 1.3 1 0 0 1 1 1 0 Esterase PHB depolymerase DLH PF01738.18 KKK16944.1 - 0.13 11.8 0.0 0.62 9.6 0.0 2.0 1 1 0 1 1 1 0 Dienelactone hydrolase family AA_permease PF00324.21 KKK16945.1 - 2.9e-114 382.3 38.5 3.6e-114 382.0 38.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KKK16945.1 - 3.7e-35 121.6 45.2 4.4e-35 121.3 45.2 1.0 1 0 0 1 1 1 1 Amino acid permease CBM-like PF14683.6 KKK16946.1 - 2.9e-38 131.3 0.0 7.1e-38 130.1 0.0 1.7 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.6 KKK16946.1 - 2.1e-14 53.0 0.5 1e-13 50.8 0.5 2.2 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain II CarboxypepD_reg PF13620.6 KKK16946.1 - 2.8e-09 37.1 4.3 9.5e-09 35.4 0.7 3.0 3 1 0 3 3 3 1 Carboxypeptidase regulatory-like domain SdrD_B PF17210.3 KKK16946.1 - 0.015 15.5 1.9 0.38 11.0 0.1 2.9 3 0 0 3 3 3 0 SdrD B-like domain CarbopepD_reg_2 PF13715.6 KKK16946.1 - 0.019 14.9 0.1 0.25 11.4 0.1 2.8 2 1 0 2 2 2 0 CarboxypepD_reg-like domain RhgB_N PF09284.10 KKK16946.1 - 0.039 13.5 0.0 0.066 12.7 0.0 1.3 1 0 0 1 1 1 0 Rhamnogalacturonan lyase B, N-terminal DUF4198 PF10670.9 KKK16946.1 - 0.077 13.4 0.1 0.36 11.2 0.0 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4198) DUF2012 PF09430.10 KKK16946.1 - 0.2 11.8 0.0 0.45 10.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2012) Cu-oxidase_3 PF07732.15 KKK16947.1 - 7.4e-39 132.4 4.1 1.2e-38 131.7 0.6 3.0 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.22 KKK16947.1 - 6e-33 114.2 0.1 4.6e-32 111.3 0.1 2.1 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 KKK16947.1 - 5.1e-17 61.9 7.3 2.3e-15 56.6 0.1 3.1 3 1 0 3 3 3 2 Multicopper oxidase Glyco_hydro_75 PF07335.11 KKK16948.1 - 1.6e-63 213.8 0.6 2.1e-63 213.5 0.6 1.1 1 0 0 1 1 1 1 Fungal chitosanase of glycosyl hydrolase group 75 UDPG_MGDP_dh_N PF03721.14 KKK16949.1 - 3.6e-36 124.5 0.1 3e-23 82.4 0.0 2.2 1 1 1 2 2 2 2 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh_C PF03720.15 KKK16949.1 - 7.8e-12 45.5 0.0 3.2e-11 43.6 0.0 2.0 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh PF00984.19 KKK16949.1 - 2.6e-10 40.4 0.0 3.9e-09 36.6 0.0 2.6 2 1 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain Ldh_1_N PF00056.23 KKK16949.1 - 0.18 11.9 0.1 25 5.0 0.0 3.2 3 0 0 3 3 3 0 lactate/malate dehydrogenase, NAD binding domain Las1 PF04031.13 KKK16971.1 - 2.6e-48 164.0 0.2 4.5e-48 163.2 0.2 1.4 1 0 0 1 1 1 1 Las1-like HAGH_C PF16123.5 KKK16971.1 - 4e-21 75.3 0.3 8.7e-21 74.2 0.3 1.5 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 KKK16971.1 - 9.3e-14 51.9 0.4 1.1e-06 28.9 0.0 2.5 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily BcrAD_BadFG PF01869.20 KKK16971.1 - 0.098 12.1 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family Peptidase_S26 PF10502.9 KKK16972.1 - 2.6e-05 24.0 0.0 0.0024 17.7 0.0 2.3 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 S-antigen PF05756.11 KKK16973.1 - 0.003 17.9 0.4 0.0048 17.2 0.4 1.2 1 0 0 1 1 1 1 S-antigen protein Glyco_transf_41 PF13844.6 KKK16990.1 - 7.2e-103 344.5 0.0 7.6e-52 176.3 0.0 3.1 1 1 1 2 2 2 2 Glycosyl transferase family 41 TPR_1 PF00515.28 KKK16990.1 - 3e-18 64.8 10.5 5.7e-05 22.8 0.0 7.0 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_2 PF07719.17 KKK16990.1 - 9.4e-14 50.4 17.8 0.0059 16.6 0.0 6.7 7 0 0 7 7 6 5 Tetratricopeptide repeat TPR_8 PF13181.6 KKK16990.1 - 5.8e-13 48.0 8.4 0.0051 16.9 0.1 6.5 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.6 KKK16990.1 - 1.5e-11 43.7 17.6 0.0001 21.9 0.1 7.2 5 2 3 8 8 8 4 TPR repeat TPR_10 PF13374.6 KKK16990.1 - 2.1e-08 33.7 17.8 0.025 14.4 0.1 6.3 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.6 KKK16990.1 - 8.2e-08 32.4 14.0 0.036 14.9 0.0 6.3 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 KKK16990.1 - 1.1e-07 32.2 10.6 0.0016 18.9 0.7 4.6 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.6 KKK16990.1 - 2.5e-07 30.6 5.4 0.25 11.8 0.2 5.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 KKK16990.1 - 5.9e-07 29.7 16.4 0.15 12.4 0.8 5.6 5 1 0 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 KKK16990.1 - 3.7e-06 27.5 19.9 0.0095 16.6 0.2 5.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 KKK16990.1 - 1.9e-05 24.3 9.3 0.13 12.4 0.0 5.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_15 PF13429.6 KKK16990.1 - 0.0058 15.9 0.4 0.3 10.2 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat BTAD PF03704.17 KKK16990.1 - 0.039 14.4 11.5 0.044 14.2 0.0 4.2 5 0 0 5 5 5 0 Bacterial transcriptional activator domain TPR_9 PF13371.6 KKK16990.1 - 0.05 13.8 0.3 0.05 13.8 0.3 4.1 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 KKK16990.1 - 0.37 11.5 3.4 1.4e+02 3.5 0.0 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF3638 PF12340.8 KKK16991.1 - 2.8e-85 285.2 0.0 5.4e-85 284.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.8 KKK16991.1 - 1.9e-15 56.0 0.0 5e-15 54.6 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) NCBP3 PF10309.9 KKK16992.1 - 2.6e-22 78.4 0.0 4.1e-22 77.8 0.0 1.3 1 0 0 1 1 1 1 Nuclear cap-binding protein subunit 3 DUF3439 PF11921.8 KKK16992.1 - 0.049 13.6 0.5 0.13 12.3 0.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Myb_DNA-binding PF00249.31 KKK16993.1 - 8.4e-27 93.1 1.6 2.5e-16 59.6 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KKK16993.1 - 2.7e-19 69.1 5.1 1.1e-15 57.6 0.1 2.9 2 1 1 3 3 3 2 Myb-like DNA-binding domain DUF2774 PF11242.8 KKK16993.1 - 0.033 14.4 0.0 0.075 13.2 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2774) Myb_DNA-bind_4 PF13837.6 KKK16993.1 - 0.047 14.1 0.3 0.21 12.0 0.0 2.2 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain FAD_binding_4 PF01565.23 KKK17006.1 - 8.7e-15 54.7 0.1 1.5e-14 53.9 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain AAA_14 PF13173.6 KKK17007.1 - 0.0051 16.9 0.0 0.011 15.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 KKK17007.1 - 0.034 13.2 0.0 0.063 12.3 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_16 PF13191.6 KKK17007.1 - 0.045 14.1 0.0 0.099 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.6 KKK17007.1 - 0.19 12.3 0.0 0.99 10.0 0.0 2.2 3 0 0 3 3 3 0 AAA domain Scs3p PF10261.9 KKK17009.1 - 5.4e-66 222.6 9.1 8.9e-65 218.6 9.1 2.0 1 1 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM 2OG-FeII_Oxy_2 PF13532.6 KKK17010.1 - 4.3e-31 108.6 0.0 7.6e-31 107.8 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Peptidase_M35 PF02102.15 KKK17011.1 - 1.7e-58 198.3 8.2 2.5e-58 197.7 8.2 1.2 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.6 KKK17011.1 - 6.4e-31 107.8 4.4 1e-30 107.2 4.4 1.3 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase Zn_clus PF00172.18 KKK17012.1 - 3.3e-07 30.3 10.8 7.6e-07 29.1 10.8 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GIT_CC PF16559.5 KKK17012.1 - 0.14 12.0 0.1 0.69 9.8 0.0 2.0 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor DIOX_N PF14226.6 KKK17013.1 - 4.7e-29 101.5 0.0 7.3e-29 100.9 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KKK17013.1 - 2.3e-17 63.3 0.0 4.1e-17 62.5 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily FAD_binding_3 PF01494.19 KKK17014.1 - 3.6e-22 79.1 0.0 6.7e-22 78.2 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KKK17014.1 - 0.00022 21.4 0.0 0.00052 20.2 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KKK17014.1 - 0.00024 20.5 0.0 0.35 10.1 0.0 2.4 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KKK17014.1 - 0.0011 19.5 0.0 0.23 12.1 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KKK17014.1 - 0.0092 15.3 0.0 0.88 8.8 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KKK17014.1 - 0.016 14.3 0.0 0.064 12.3 0.0 1.8 2 0 0 2 2 2 0 FAD binding domain DAO PF01266.24 KKK17014.1 - 0.11 12.0 0.1 2.1 7.9 0.0 2.5 2 1 1 3 3 3 0 FAD dependent oxidoreductase ADH_zinc_N PF00107.26 KKK17015.1 - 7.2e-12 45.4 0.1 3.1e-11 43.4 0.0 2.2 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KKK17015.1 - 0.00016 21.5 0.1 0.00031 20.6 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ketoacyl-synt PF00109.26 KKK17016.1 - 3e-74 249.8 0.0 6.1e-74 248.8 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 KKK17016.1 - 1.5e-51 174.9 0.0 4.6e-51 173.3 0.0 1.9 1 0 0 1 1 1 1 KR domain PS-DH PF14765.6 KKK17016.1 - 1.2e-47 162.6 0.0 2.5e-47 161.6 0.0 1.6 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 KKK17016.1 - 1.1e-39 136.9 0.1 2e-39 136.0 0.1 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KKK17016.1 - 6.5e-27 93.9 0.0 1.7e-26 92.5 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.12 KKK17016.1 - 2.7e-19 69.7 0.0 1.1e-18 67.7 0.0 2.2 2 0 0 2 2 1 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 KKK17016.1 - 2.1e-18 66.8 0.0 8.3e-18 64.9 0.0 2.1 2 0 0 2 2 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_25 PF13649.6 KKK17016.1 - 1.2e-12 48.3 0.0 7.5e-12 45.8 0.0 2.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KKK17016.1 - 6.9e-12 45.5 0.0 1.6e-11 44.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KKK17016.1 - 1.1e-11 44.7 0.0 3e-11 43.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KKK17016.1 - 6.2e-11 42.8 0.0 1.8e-10 41.4 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.25 KKK17016.1 - 2.4e-10 40.2 0.5 1.5e-09 37.6 0.0 2.5 3 0 0 3 3 3 1 short chain dehydrogenase Thiolase_N PF00108.23 KKK17016.1 - 3.4e-05 23.3 0.1 6.9e-05 22.3 0.1 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Ubie_methyltran PF01209.18 KKK17016.1 - 0.0002 20.8 0.0 0.00038 19.9 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family adh_short_C2 PF13561.6 KKK17016.1 - 0.00049 19.7 0.0 0.0012 18.4 0.0 1.6 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Methyltransf_16 PF10294.9 KKK17016.1 - 0.012 15.3 0.0 0.026 14.3 0.0 1.5 1 0 0 1 1 1 0 Lysine methyltransferase DUF938 PF06080.12 KKK17016.1 - 0.016 15.0 0.0 0.036 13.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF938) DREV PF05219.12 KKK17016.1 - 0.067 12.3 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_33 PF10017.9 KKK17016.1 - 0.093 11.9 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent GDP_Man_Dehyd PF16363.5 KKK17016.1 - 0.1 12.0 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase DLH PF01738.18 KKK17017.1 - 7.8e-15 55.0 0.0 1.7e-14 53.9 0.0 1.5 1 1 0 1 1 1 1 Dienelactone hydrolase family DUF2024 PF09630.10 KKK17018.1 - 0.11 12.4 0.0 0.31 10.9 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF2024) zf-C2H2_4 PF13894.6 KKK17018.1 - 0.29 12.1 1.0 0.69 10.9 1.0 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger AD PF09793.9 KKK17019.1 - 1.8e-28 98.5 0.0 2.7e-28 97.9 0.0 1.3 1 0 0 1 1 1 1 Anticodon-binding domain 6PGD PF00393.19 KKK17020.1 - 2.3e-128 427.6 0.0 2.9e-128 427.3 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 KKK17020.1 - 7.2e-51 172.5 0.0 1.1e-50 171.8 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 KKK17020.1 - 0.017 15.3 0.0 0.048 13.9 0.0 1.8 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase ANT PF03374.14 KKK17020.1 - 0.21 11.9 0.0 17 5.8 0.0 2.5 2 0 0 2 2 2 0 Phage antirepressor protein KilAC domain RRM_1 PF00076.22 KKK17021.1 - 1.6e-17 63.0 0.0 2.6e-17 62.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ABC2_membrane PF01061.24 KKK17022.1 - 3.4e-84 281.5 60.2 2.5e-47 161.0 24.8 3.3 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.27 KKK17022.1 - 6.8e-35 120.6 0.0 9.2e-17 61.8 0.0 2.6 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 KKK17022.1 - 3.1e-32 110.3 11.8 3.2e-28 97.5 0.0 3.3 3 0 0 3 3 2 2 CDR ABC transporter ABC2_membrane_3 PF12698.7 KKK17022.1 - 8.4e-11 41.6 43.0 2.1e-06 27.1 21.9 2.3 2 0 0 2 2 2 2 ABC-2 family transporter protein ABC_trans_N PF14510.6 KKK17022.1 - 9.7e-10 38.9 0.1 3.3e-09 37.2 0.1 2.0 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_21 PF13304.6 KKK17022.1 - 4.7e-08 33.2 0.0 0.0058 16.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KKK17022.1 - 1.4e-06 28.8 1.1 0.00018 22.0 0.1 2.9 2 1 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 KKK17022.1 - 5.2e-06 27.0 0.0 0.0015 19.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KKK17022.1 - 9.8e-06 25.9 0.8 0.01 16.1 0.1 3.7 3 1 0 3 3 2 1 AAA domain AAA_29 PF13555.6 KKK17022.1 - 1.1e-05 25.1 0.1 0.015 15.0 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KKK17022.1 - 2.1e-05 24.5 0.2 7.5e-05 22.7 0.0 1.8 2 0 0 2 2 2 1 RsgA GTPase AAA_33 PF13671.6 KKK17022.1 - 0.00011 22.3 0.0 0.0036 17.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 KKK17022.1 - 0.00015 22.4 0.4 0.0083 16.7 0.0 2.6 3 0 0 3 3 2 1 AAA domain cobW PF02492.19 KKK17022.1 - 0.00022 20.8 0.1 0.0041 16.7 0.0 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.23 KKK17022.1 - 0.00077 19.5 0.3 0.061 13.4 0.1 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_17 PF13207.6 KKK17022.1 - 0.0016 18.8 0.1 0.025 15.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KKK17022.1 - 0.0022 17.6 0.7 0.013 15.1 0.1 2.2 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KKK17022.1 - 0.0031 17.4 0.3 0.085 12.8 0.1 2.6 2 0 0 2 2 2 1 NACHT domain AAA_30 PF13604.6 KKK17022.1 - 0.0051 16.6 0.3 0.081 12.6 0.1 2.2 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 KKK17022.1 - 0.0052 16.2 0.2 3.9 6.9 0.0 3.0 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_28 PF13521.6 KKK17022.1 - 0.0064 16.7 0.1 0.0064 16.7 0.1 2.3 3 0 0 3 3 2 1 AAA domain dNK PF01712.19 KKK17022.1 - 0.016 15.1 0.0 0.035 14.0 0.0 1.5 1 0 0 1 1 1 0 Deoxynucleoside kinase AAA PF00004.29 KKK17022.1 - 0.022 15.2 0.0 0.76 10.2 0.0 2.9 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) FtsK_SpoIIIE PF01580.18 KKK17022.1 - 0.043 13.1 0.2 5.3 6.3 0.1 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family ABC_ATPase PF09818.9 KKK17022.1 - 0.056 12.2 0.9 0.28 9.9 0.5 2.3 3 0 0 3 3 3 0 Predicted ATPase of the ABC class RNA_helicase PF00910.22 KKK17022.1 - 0.15 12.4 0.1 4.1 7.9 0.0 2.6 2 0 0 2 2 2 0 RNA helicase DUF3600 PF12207.8 KKK17022.1 - 0.16 11.9 0.0 8.6 6.3 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3600) DnaB_C PF03796.15 KKK17022.1 - 0.16 11.3 0.1 2.8 7.2 0.0 2.2 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain Ploopntkinase3 PF18751.1 KKK17022.1 - 0.19 11.6 0.3 3.9 7.4 0.0 2.5 3 0 0 3 3 2 0 P-loop Nucleotide Kinase3 TsaE PF02367.17 KKK17022.1 - 0.19 11.7 1.2 0.35 10.9 0.4 1.7 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Dynamin_N PF00350.23 KKK17022.1 - 0.34 11.0 0.8 2.4 8.2 0.1 2.6 4 0 0 4 4 3 0 Dynamin family PBP1_TM PF14812.6 KKK17022.1 - 0.77 10.2 4.2 11 6.5 1.0 2.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal 2OG-FeII_Oxy_2 PF13532.6 KKK17023.1 - 2.4e-25 89.9 0.0 3.6e-25 89.3 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Ribophorin_II PF05817.14 KKK17032.1 - 1.7e-28 99.6 0.0 2e-28 99.3 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II Acyl_transf_3 PF01757.22 KKK17044.1 - 1.1e-22 80.6 23.7 2.2e-22 79.6 23.6 1.6 1 1 0 1 1 1 1 Acyltransferase family TAFII28 PF04719.14 KKK17045.1 - 1.9e-25 88.8 0.1 4.8e-25 87.5 0.1 1.6 1 1 0 1 1 1 1 hTAFII28-like protein conserved region DUF3915 PF13054.6 KKK17045.1 - 0.16 11.9 0.5 0.37 10.8 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) SAM_decarbox PF01536.16 KKK17046.1 - 3.6e-130 434.1 0.0 4.6e-130 433.7 0.0 1.1 1 0 0 1 1 1 1 Adenosylmethionine decarboxylase TAF6_C PF07571.13 KKK17046.1 - 4.4e-32 110.3 0.0 1e-31 109.1 0.0 1.7 1 0 0 1 1 1 1 TAF6 C-terminal HEAT repeat domain TAF PF02969.17 KKK17046.1 - 7.4e-24 83.7 0.1 1.9e-23 82.4 0.1 1.8 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Histone PF00125.24 KKK17046.1 - 0.0025 18.1 0.3 0.0071 16.7 0.3 1.8 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KKK17046.1 - 0.015 15.5 0.0 0.042 14.1 0.0 1.7 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 KKK17046.1 - 0.11 12.5 0.3 0.28 11.3 0.3 1.6 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit CRAL_TRIO PF00650.20 KKK17047.1 - 1.1e-14 54.4 0.2 3.5e-14 52.8 0.2 1.7 1 1 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KKK17047.1 - 0.00011 22.3 0.0 0.00023 21.3 0.0 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 KKK17047.1 - 0.071 13.3 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain Aldedh PF00171.22 KKK17048.1 - 2.2e-152 507.8 0.2 3.5e-152 507.1 0.2 1.2 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Gln-synt_C PF00120.24 KKK17048.1 - 5.7e-62 209.7 0.0 1.6e-61 208.3 0.0 1.7 1 1 0 1 1 1 1 Glutamine synthetase, catalytic domain Amidohydro_2 PF04909.14 KKK17048.1 - 1e-14 55.0 0.0 2.1e-14 54.0 0.0 1.5 1 0 0 1 1 1 1 Amidohydrolase Ribosomal_60s PF00428.19 KKK17109.1 - 8.2e-05 23.1 0.0 9.6e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein EF-hand_14 PF17959.1 KKK17109.1 - 0.012 15.9 0.0 0.012 15.9 0.0 1.1 1 0 0 1 1 1 0 EF-hand domain Type2_restr_D3 PF16902.5 KKK17109.1 - 0.063 13.2 0.0 0.069 13.1 0.0 1.1 1 0 0 1 1 1 0 Type-2 restriction enzyme D3 domain Fungal_trans PF04082.18 KKK17110.1 - 5.7e-15 55.1 2.1 8.8e-15 54.4 2.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK17110.1 - 7.2e-09 35.6 10.8 1.5e-08 34.6 10.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_3 PF01494.19 KKK17112.1 - 7.1e-16 58.4 0.4 7.1e-10 38.6 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KKK17112.1 - 4.6e-09 36.4 0.7 1.3e-08 34.9 0.7 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KKK17112.1 - 2e-06 27.3 0.1 3.6e-06 26.4 0.1 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KKK17112.1 - 9e-06 25.3 0.0 1.4e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.24 KKK17112.1 - 1.9e-05 24.4 5.7 2.7e-05 23.9 4.7 1.7 1 1 1 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KKK17112.1 - 5.4e-05 22.5 0.0 7.6e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.24 KKK17112.1 - 0.00057 19.3 0.3 0.0011 18.4 0.1 1.5 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 KKK17112.1 - 0.0013 19.2 1.0 0.0039 17.7 1.0 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KKK17112.1 - 0.0043 16.2 0.8 0.0069 15.5 0.8 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Lycopene_cycl PF05834.12 KKK17112.1 - 0.005 15.9 0.0 0.0069 15.5 0.0 1.1 1 0 0 1 1 1 1 Lycopene cyclase protein Rossmann-like PF10727.9 KKK17112.1 - 0.0063 16.4 0.5 0.012 15.5 0.5 1.5 1 0 0 1 1 1 1 Rossmann-like domain Pyr_redox_3 PF13738.6 KKK17112.1 - 0.015 14.6 0.9 0.077 12.2 1.1 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KKK17112.1 - 0.022 13.5 1.2 0.034 12.8 1.2 1.3 1 0 0 1 1 1 0 HI0933-like protein Trp_halogenase PF04820.14 KKK17112.1 - 0.039 12.8 1.0 0.3 9.9 0.8 2.0 2 0 0 2 2 2 0 Tryptophan halogenase AlaDh_PNT_C PF01262.21 KKK17112.1 - 0.041 13.2 0.3 0.074 12.3 0.3 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain MCRA PF06100.11 KKK17112.1 - 0.042 12.7 0.2 0.072 11.9 0.2 1.3 1 0 0 1 1 1 0 MCRA family ApbA PF02558.16 KKK17112.1 - 4.2 7.0 5.0 0.87 9.2 1.2 1.8 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Kelch_5 PF13854.6 KKK17113.1 - 1.7e-16 59.8 1.9 8.4e-15 54.4 1.0 3.5 3 0 0 3 3 3 1 Kelch motif Kelch_1 PF01344.25 KKK17113.1 - 8.5e-06 25.3 0.1 0.014 14.9 0.1 3.5 3 0 0 3 3 3 2 Kelch motif Kelch_6 PF13964.6 KKK17113.1 - 9.6e-06 25.7 4.8 0.036 14.4 0.2 4.8 5 0 0 5 5 5 2 Kelch motif Kelch_3 PF13415.6 KKK17113.1 - 5.2e-05 23.4 5.9 0.056 13.7 0.1 4.7 4 0 0 4 4 4 1 Galactose oxidase, central domain PTP_tm PF18861.1 KKK17113.1 - 0.01 15.8 0.0 0.02 14.9 0.0 1.5 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J Kelch_2 PF07646.15 KKK17113.1 - 0.015 15.3 0.5 12 6.0 0.1 4.5 4 0 0 4 4 4 0 Kelch motif DUF4381 PF14316.6 KKK17113.1 - 0.12 12.6 0.0 0.26 11.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) MSP1a PF11670.8 KKK17113.1 - 0.15 11.3 1.1 0.25 10.6 1.1 1.2 1 0 0 1 1 1 0 Major surface protein 1a (MSP1a) Gram_pos_anchor PF00746.21 KKK17113.1 - 0.41 10.6 3.2 1.1 9.2 2.4 2.3 2 0 0 2 2 2 0 LPXTG cell wall anchor motif COPIIcoated_ERV PF07970.12 KKK17116.1 - 5.9e-35 121.1 0.0 9.5e-35 120.4 0.0 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 KKK17116.1 - 4.1e-23 81.5 0.0 7.2e-23 80.8 0.0 1.4 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Pkinase PF00069.25 KKK17117.1 - 6.4e-54 183.1 0.0 1e-53 182.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK17117.1 - 1.2e-19 70.7 0.0 2e-19 69.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KKK17117.1 - 0.11 12.4 0.0 0.51 10.2 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 KKK17117.1 - 0.12 11.8 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Phage_GP20 PF06810.11 KKK17118.1 - 0.0011 18.8 8.2 0.0011 18.8 8.2 5.2 3 1 2 5 5 5 1 Phage minor structural protein GP20 GAS PF13851.6 KKK17118.1 - 0.0018 17.7 11.1 0.0018 17.7 11.1 4.7 3 1 1 4 4 4 1 Growth-arrest specific micro-tubule binding TMEM192 PF14802.6 KKK17118.1 - 0.19 10.8 0.5 3 6.9 0.0 2.6 2 0 0 2 2 2 0 TMEM192 family Herpes_UL6 PF01763.16 KKK17118.1 - 1.6 7.1 19.0 4.6 5.6 11.4 2.8 2 1 0 2 2 2 0 Herpesvirus UL6 like Baculo_PEP_C PF04513.12 KKK17118.1 - 2.6 8.1 10.3 11 6.1 2.9 2.6 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Dak2 PF02734.17 KKK17118.1 - 7 6.5 10.3 1 9.2 4.4 2.4 2 0 0 2 2 2 0 DAK2 domain Pkinase_fungal PF17667.1 KKK17119.1 - 3.4e-109 365.3 0.0 1.8e-105 353.1 0.0 2.1 1 1 0 1 1 1 1 Fungal protein kinase Maf1 PF09174.10 KKK17120.1 - 5.2e-63 212.3 0.0 9.2e-63 211.5 0.0 1.4 1 0 0 1 1 1 1 Maf1 regulator Clat_adaptor_s PF01217.20 KKK17120.1 - 5.1e-32 110.8 1.1 7.6e-32 110.2 1.1 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain ABC_tran PF00005.27 KKK17121.1 - 3.5e-46 157.1 0.0 6.2e-28 98.0 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KKK17121.1 - 5.7e-35 121.3 22.5 1.4e-22 80.7 10.7 3.5 3 0 0 3 3 3 3 ABC transporter transmembrane region SMC_N PF02463.19 KKK17121.1 - 5.8e-12 45.5 3.8 0.00018 21.0 0.1 4.2 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KKK17121.1 - 1.4e-06 28.4 6.0 0.016 15.1 0.1 4.3 2 2 1 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KKK17121.1 - 2.4e-06 28.2 3.4 0.00044 20.8 0.3 2.5 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KKK17121.1 - 8.7e-06 25.4 1.3 0.0064 16.1 0.0 3.5 3 1 0 3 3 3 1 AAA domain AAA_22 PF13401.6 KKK17121.1 - 2.4e-05 24.6 3.0 0.046 14.0 0.0 3.3 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KKK17121.1 - 3.1e-05 23.6 4.5 0.0044 16.7 0.3 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KKK17121.1 - 7e-05 22.8 0.1 0.52 10.2 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 KKK17121.1 - 8.3e-05 22.7 0.0 0.11 12.5 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KKK17121.1 - 0.00012 22.5 2.0 0.34 11.3 0.0 3.4 2 1 0 2 2 2 2 AAA ATPase domain NACHT PF05729.12 KKK17121.1 - 0.00076 19.4 0.1 1.4 8.8 0.0 2.9 2 0 0 2 2 2 2 NACHT domain AAA PF00004.29 KKK17121.1 - 0.0011 19.4 0.0 1.2 9.5 0.0 3.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.6 KKK17121.1 - 0.0016 18.2 0.0 1.5 8.4 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain T2SSE PF00437.20 KKK17121.1 - 0.0024 17.0 1.2 0.57 9.2 0.1 2.5 2 0 0 2 2 2 1 Type II/IV secretion system protein cobW PF02492.19 KKK17121.1 - 0.0043 16.6 1.5 0.88 9.1 0.2 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 KKK17121.1 - 0.0074 16.0 0.4 4.2 7.0 0.0 3.0 2 1 0 2 2 2 1 AAA domain AAA_7 PF12775.7 KKK17121.1 - 0.011 15.3 0.4 2.2 7.7 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region SbcCD_C PF13558.6 KKK17121.1 - 0.043 14.0 0.1 15 5.9 0.0 2.9 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit TsaE PF02367.17 KKK17121.1 - 0.067 13.2 0.4 3.8 7.5 0.2 2.8 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 KKK17121.1 - 0.075 13.4 0.0 18 5.8 0.0 2.6 2 0 0 2 2 2 0 RNA helicase TrwB_AAD_bind PF10412.9 KKK17121.1 - 0.082 11.8 2.8 3.2 6.6 0.1 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_13 PF13166.6 KKK17121.1 - 0.12 11.0 0.6 6.9 5.2 0.0 2.7 3 0 0 3 3 3 0 AAA domain AAA_33 PF13671.6 KKK17121.1 - 0.16 12.2 0.6 4.2 7.5 0.0 2.7 2 1 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 KKK17121.1 - 0.16 11.3 0.1 2.6 7.4 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI DUF87 PF01935.17 KKK17121.1 - 0.17 11.9 4.1 0.059 13.5 0.6 1.9 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_11 PF13086.6 KKK17121.1 - 0.2 11.4 0.4 2 8.2 0.0 2.5 3 0 0 3 3 3 0 AAA domain DUF2075 PF09848.9 KKK17121.1 - 0.23 10.7 1.4 2.9 7.0 0.0 2.5 3 0 0 3 3 2 0 Uncharacterized conserved protein (DUF2075) AAA_5 PF07728.14 KKK17121.1 - 0.49 10.4 1.5 12 5.9 0.1 2.8 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) PduV-EutP PF10662.9 KKK17121.1 - 0.74 9.6 2.6 8.6 6.1 0.2 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ABC_ATPase PF09818.9 KKK17121.1 - 1.1 7.9 3.1 0.73 8.6 0.2 2.0 2 0 0 2 2 2 0 Predicted ATPase of the ABC class IstB_IS21 PF01695.17 KKK17121.1 - 1.3 8.7 4.9 15 5.3 0.0 3.7 4 0 0 4 4 4 0 IstB-like ATP binding protein FeoB_C PF07664.12 KKK17121.1 - 1.5 8.6 5.3 0.34 10.6 0.2 2.8 2 0 0 2 2 1 0 Ferrous iron transport protein B C terminus Pex24p PF06398.11 KKK17122.1 - 5e-63 213.3 0.0 5.9e-63 213.0 0.0 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin DUF4568 PF15132.6 KKK17122.1 - 0.09 12.1 0.4 0.15 11.4 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4568) Pkinase PF00069.25 KKK17126.1 - 4.5e-67 226.2 1.3 4.1e-66 223.1 1.3 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK17126.1 - 9.2e-52 175.9 0.1 1.6e-51 175.1 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 KKK17126.1 - 4.8e-24 84.5 0.1 6.1e-23 80.9 0.0 2.5 2 0 0 2 2 2 1 P21-Rho-binding domain PH_11 PF15413.6 KKK17126.1 - 3.5e-15 56.3 0.0 1.1e-14 54.7 0.0 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 KKK17126.1 - 1e-06 29.2 0.0 2.5e-06 27.9 0.0 1.7 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.6 KKK17126.1 - 4.4e-06 26.2 0.0 7.8e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KKK17126.1 - 3.3e-05 23.0 0.2 7.6e-05 21.8 0.2 1.6 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 KKK17126.1 - 5.1e-05 22.2 0.0 5.1e-05 22.2 0.0 2.0 3 0 0 3 3 3 1 Fungal protein kinase KIND PF16474.5 KKK17126.1 - 0.011 15.6 3.3 0.11 12.4 0.0 2.4 2 0 0 2 2 2 0 Kinase non-catalytic C-lobe domain Seadorna_VP7 PF07387.11 KKK17126.1 - 0.022 13.8 0.1 0.041 12.9 0.1 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.23 KKK17126.1 - 0.21 11.5 5.8 0.1 12.5 0.3 2.6 2 1 1 3 3 3 0 Phosphotransferase enzyme family NAD_kinase PF01513.21 KKK17127.1 - 8.3e-47 159.8 0.0 3.9e-46 157.6 0.0 1.7 1 1 0 1 1 1 1 ATP-NAD kinase TPR_2 PF07719.17 KKK17128.1 - 1e-27 93.9 25.0 0.00085 19.3 0.1 11.7 11 0 0 11 11 11 8 Tetratricopeptide repeat Acyltransferase PF01553.21 KKK17128.1 - 2.9e-26 91.7 0.0 5.8e-26 90.7 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase TPR_1 PF00515.28 KKK17128.1 - 5.5e-25 86.1 18.2 0.00012 21.7 0.0 10.5 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_8 PF13181.6 KKK17128.1 - 1.2e-18 65.7 20.3 0.00074 19.5 0.0 11.1 11 0 0 11 11 10 5 Tetratricopeptide repeat TPR_19 PF14559.6 KKK17128.1 - 2.6e-15 56.7 17.5 0.009 16.5 0.0 8.3 6 3 3 9 9 9 4 Tetratricopeptide repeat TPR_14 PF13428.6 KKK17128.1 - 8.4e-14 51.1 30.6 0.059 14.2 0.3 11.9 11 1 1 12 12 12 4 Tetratricopeptide repeat Acyltransf_C PF16076.5 KKK17128.1 - 3.9e-12 46.1 0.3 1.7e-11 44.0 0.0 2.3 2 0 0 2 2 2 1 Acyltransferase C-terminus TPR_6 PF13174.6 KKK17128.1 - 6.3e-08 32.8 25.5 0.84 10.4 0.1 12.2 13 0 0 13 13 13 2 Tetratricopeptide repeat TPR_16 PF13432.6 KKK17128.1 - 6.7e-08 33.1 27.1 0.047 14.4 1.0 8.7 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_12 PF13424.6 KKK17128.1 - 1.3e-06 28.6 29.0 0.12 12.7 1.3 8.8 6 3 2 8 8 8 3 Tetratricopeptide repeat TPR_11 PF13414.6 KKK17128.1 - 5.2e-06 26.0 19.7 0.3 10.8 0.1 7.8 8 1 1 9 9 9 3 TPR repeat TPR_7 PF13176.6 KKK17128.1 - 6.9e-06 25.7 23.7 0.00052 19.8 0.4 8.6 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_17 PF13431.6 KKK17128.1 - 1.9e-05 24.7 13.4 2.9 8.5 0.0 8.4 9 0 0 9 9 8 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KKK17128.1 - 0.0002 21.5 4.6 0.57 10.4 0.2 5.4 4 0 0 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 KKK17128.1 - 8.9 6.3 33.0 0.26 11.2 0.2 7.9 9 0 0 9 9 8 0 Tetratricopeptide repeat Pkinase PF00069.25 KKK17129.1 - 1.1e-69 234.7 0.0 1.8e-69 234.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK17129.1 - 3.7e-39 134.6 0.0 1e-38 133.1 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 KKK17129.1 - 1.2e-16 60.2 0.4 2.2e-16 59.4 0.4 1.4 1 0 0 1 1 1 1 Kinase associated domain 1 Haspin_kinase PF12330.8 KKK17129.1 - 4.1e-06 26.0 0.0 4.1e-06 26.0 0.0 1.5 2 0 0 2 2 2 1 Haspin like kinase domain Kinase-like PF14531.6 KKK17129.1 - 4.9e-05 22.8 0.0 9.9e-05 21.8 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KKK17129.1 - 0.0002 20.8 0.1 0.00037 19.9 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KKK17129.1 - 0.0047 16.9 0.0 0.023 14.6 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 KKK17129.1 - 0.018 14.7 0.4 0.058 13.0 0.4 1.8 1 1 0 1 1 1 0 RIO1 family YrbL-PhoP_reg PF10707.9 KKK17129.1 - 0.064 12.8 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL UBD PF16455.5 KKK17130.1 - 4.5e-41 139.3 0.0 6.6e-41 138.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-binding domain ubiquitin PF00240.23 KKK17130.1 - 1.1e-05 25.1 0.0 1.6e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Med26_C PF15693.5 KKK17130.1 - 0.074 13.2 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 Mediator complex subunit 26 C-terminal DUF1604 PF07713.13 KKK17131.1 - 2e-43 146.1 3.2 5.3e-43 144.7 1.2 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1604) G-patch PF01585.23 KKK17131.1 - 5.8e-08 32.5 1.2 1.5e-07 31.2 1.2 1.7 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 KKK17131.1 - 0.039 14.0 2.0 0.14 12.2 0.4 2.7 1 1 1 2 2 2 0 G-patch domain Pkinase PF00069.25 KKK17132.1 - 8.1e-66 222.1 0.0 1.6e-65 221.1 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK17132.1 - 2.9e-35 121.8 0.0 5.4e-26 91.4 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 KKK17132.1 - 2.4e-06 26.6 0.1 4.6e-06 25.7 0.1 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KKK17132.1 - 3.1e-05 23.4 0.5 0.0017 17.7 0.0 2.5 3 0 0 3 3 3 1 Kinase-like APH PF01636.23 KKK17132.1 - 0.0028 17.6 0.0 0.0075 16.2 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family FtsX_ECD PF18075.1 KKK17132.1 - 0.019 15.6 0.0 0.087 13.5 0.0 2.2 1 0 0 1 1 1 0 FtsX extracellular domain Seadorna_VP7 PF07387.11 KKK17132.1 - 0.021 13.9 0.0 0.039 13.0 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 FERM_f0 PF16511.5 KKK17132.1 - 0.071 13.4 0.1 0.26 11.6 0.1 1.9 1 0 0 1 1 1 0 N-terminal or F0 domain of Talin-head FERM FTA2 PF13095.6 KKK17132.1 - 0.14 11.7 0.1 0.53 9.9 0.0 1.9 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Ammonium_transp PF00909.21 KKK17133.1 - 9.7e-120 399.9 30.4 1.1e-119 399.7 30.4 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family DUF441 PF04284.13 KKK17133.1 - 0.052 13.6 1.4 0.44 10.6 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF441) Phage_holin_2_1 PF04971.12 KKK17133.1 - 3.9 7.6 7.3 0.32 11.0 0.8 2.7 3 0 0 3 3 3 0 Bacteriophage P21 holin S Tubulin PF00091.25 KKK17134.1 - 5e-68 229.2 0.0 1.1e-67 228.1 0.0 1.5 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KKK17134.1 - 1.4e-44 151.3 0.1 2.3e-44 150.6 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 KKK17134.1 - 4.5e-05 23.7 0.0 0.00012 22.4 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 KKK17134.1 - 0.0014 17.9 0.0 0.024 13.9 0.0 2.1 2 0 0 2 2 2 1 Tubulin like Tubulin_3 PF14881.6 KKK17134.1 - 0.0036 17.0 0.0 0.0065 16.2 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain TrmK PF04816.12 KKK17134.1 - 0.17 11.4 0.0 0.29 10.7 0.0 1.3 1 0 0 1 1 1 0 tRNA (adenine(22)-N(1))-methyltransferase RRM_1 PF00076.22 KKK17135.1 - 2.1e-11 43.5 0.1 7.1e-05 22.6 0.0 3.1 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4651 PF15513.6 KKK17135.1 - 0.022 14.5 0.0 3 7.7 0.0 3.1 3 1 0 3 3 3 0 Domain of unknown function (DUF4651) DAGK_cat PF00781.24 KKK17136.1 - 1.3e-25 89.5 0.0 2e-25 88.8 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Adaptin_N PF01602.20 KKK17137.1 - 1.4e-95 320.8 8.9 2.2e-95 320.2 8.9 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Coatamer_beta_C PF07718.12 KKK17137.1 - 2.6e-58 195.9 0.6 5.7e-58 194.8 0.6 1.6 1 0 0 1 1 1 1 Coatomer beta C-terminal region Coatomer_b_Cpla PF14806.6 KKK17137.1 - 2.9e-56 188.9 0.0 7.7e-56 187.6 0.0 1.8 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Cnd1 PF12717.7 KKK17137.1 - 4.6e-14 52.8 5.0 3.3e-09 37.0 0.1 2.9 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KKK17137.1 - 8.4e-07 29.3 0.2 8.3e-05 22.9 0.0 5.2 3 1 3 6 6 6 2 HEAT repeats Coatomer_g_Cpla PF16381.5 KKK17137.1 - 5.4e-05 23.3 0.0 0.00049 20.2 0.0 2.5 2 0 0 2 2 2 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT PF02985.22 KKK17137.1 - 0.0045 17.1 1.8 1.5 9.3 0.1 4.4 4 0 0 4 4 4 1 HEAT repeat AP4E_app_platf PF14807.6 KKK17137.1 - 0.0063 16.9 0.2 0.024 15.0 0.2 2.1 1 0 0 1 1 1 1 Adaptin AP4 complex epsilon appendage platform HEAT_EZ PF13513.6 KKK17137.1 - 0.08 13.5 0.2 4 8.0 0.0 3.6 2 0 0 2 2 2 0 HEAT-like repeat Mago_nashi PF02792.14 KKK17138.1 - 1.4e-73 245.6 0.2 1.9e-73 245.3 0.2 1.2 1 0 0 1 1 1 1 Mago nashi protein DUF5375 PF17345.2 KKK17138.1 - 0.13 12.2 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5375) Vac_ImportDeg PF09783.9 KKK17139.1 - 1.5e-69 232.9 0.7 1.8e-69 232.7 0.7 1.1 1 0 0 1 1 1 1 Vacuolar import and degradation protein ABC2_membrane PF01061.24 KKK17140.1 - 1.1e-88 296.2 53.2 3.1e-44 150.9 24.5 2.5 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 KKK17140.1 - 5.7e-36 124.1 0.1 1.2e-17 64.7 0.0 3.0 3 0 0 3 3 3 2 ABC transporter PDR_CDR PF06422.12 KKK17140.1 - 9.1e-33 112.0 2.3 2.6e-30 104.2 0.1 3.9 4 0 0 4 4 3 2 CDR ABC transporter ABC_trans_N PF14510.6 KKK17140.1 - 3e-17 63.0 0.0 9e-17 61.5 0.0 1.9 1 0 0 1 1 1 1 ABC-transporter N-terminal ABC2_membrane_3 PF12698.7 KKK17140.1 - 1.9e-07 30.5 43.9 0.00071 18.8 20.2 2.5 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_25 PF13481.6 KKK17140.1 - 1.1e-05 25.2 0.1 0.0015 18.1 0.1 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KKK17140.1 - 3.3e-05 24.3 0.1 0.0057 17.1 0.0 2.7 2 1 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 KKK17140.1 - 3.9e-05 23.6 0.0 0.0065 16.4 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_33 PF13671.6 KKK17140.1 - 6.9e-05 23.0 0.0 0.18 11.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 KKK17140.1 - 0.00018 22.1 0.0 0.0044 17.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KKK17140.1 - 0.001 18.8 1.8 0.061 13.1 0.1 3.1 3 0 0 3 3 3 1 P-loop containing region of AAA domain cobW PF02492.19 KKK17140.1 - 0.0074 15.9 1.2 0.092 12.3 0.1 2.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 KKK17140.1 - 0.011 15.6 2.0 3.7 7.4 0.2 2.9 3 0 0 3 3 3 0 NACHT domain SMC_N PF02463.19 KKK17140.1 - 0.013 14.9 0.1 0.94 8.9 0.0 3.2 3 1 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KKK17140.1 - 0.014 15.6 0.2 1.3 9.2 0.0 2.9 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 KKK17140.1 - 0.016 15.3 0.1 6.7 6.8 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase RNA_helicase PF00910.22 KKK17140.1 - 0.017 15.5 0.2 4.4 7.8 0.1 2.7 2 0 0 2 2 2 0 RNA helicase AAA_30 PF13604.6 KKK17140.1 - 0.021 14.5 1.2 0.43 10.3 0.2 2.6 3 0 0 3 3 3 0 AAA domain AAA_17 PF13207.6 KKK17140.1 - 0.029 14.8 0.1 0.4 11.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.6 KKK17140.1 - 0.033 14.0 2.6 2 8.2 0.0 3.4 4 0 0 4 4 3 0 AAA domain, putative AbiEii toxin, Type IV TA system dNK PF01712.19 KKK17140.1 - 0.12 12.2 0.0 4.5 7.1 0.0 2.5 2 0 0 2 2 2 0 Deoxynucleoside kinase AAA PF00004.29 KKK17140.1 - 0.17 12.3 0.1 13 6.2 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Nop52 PF05997.12 KKK17141.1 - 3.7e-53 180.5 0.3 2.1e-39 135.5 0.3 2.2 2 0 0 2 2 2 2 Nucleolar protein,Nop52 FancD2 PF14631.6 KKK17141.1 - 0.015 12.8 0.7 0.019 12.4 0.7 1.1 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease RNA_pol_Rpc82 PF05645.13 KKK17141.1 - 0.015 15.1 0.1 0.026 14.3 0.1 1.3 1 0 0 1 1 1 0 RNA polymerase III subunit RPC82 RNA_pol_Rpc4 PF05132.14 KKK17141.1 - 0.016 15.6 0.2 0.031 14.7 0.2 1.5 1 0 0 1 1 1 0 RNA polymerase III RPC4 DUF4228 PF14009.6 KKK17141.1 - 0.018 15.4 0.4 0.037 14.4 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) NARP1 PF12569.8 KKK17141.1 - 0.025 13.5 2.2 0.038 12.9 2.2 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 FAM181 PF15238.6 KKK17141.1 - 0.061 13.2 2.9 0.1 12.4 2.9 1.3 1 0 0 1 1 1 0 FAM181 HTH_IclR PF09339.10 KKK17141.1 - 0.074 12.9 0.1 0.39 10.5 0.1 2.2 1 1 0 1 1 1 0 IclR helix-turn-helix domain Presenilin PF01080.17 KKK17141.1 - 0.12 11.1 2.2 0.16 10.7 2.2 1.2 1 0 0 1 1 1 0 Presenilin NOT2_3_5 PF04153.18 KKK17141.1 - 0.16 12.1 0.1 0.16 12.1 0.1 2.0 2 0 0 2 2 2 0 NOT2 / NOT3 / NOT5 family NPR3 PF03666.13 KKK17141.1 - 0.57 8.9 4.5 0.82 8.4 4.5 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 MCM_bind PF09739.9 KKK17141.1 - 0.94 7.8 3.6 1.3 7.3 3.6 1.2 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor DUF4820 PF16091.5 KKK17141.1 - 3.3 7.0 6.8 0.52 9.6 2.6 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) PBP1_TM PF14812.6 KKK17141.1 - 4.6 7.7 12.7 0.087 13.2 1.2 2.9 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Transp_cyt_pur PF02133.15 KKK17142.1 - 4.7e-14 52.0 36.5 9.6e-14 51.0 36.5 1.5 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin AAA PF00004.29 KKK17143.1 - 2.2e-37 128.4 0.0 3.4e-37 127.8 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 KKK17143.1 - 2.1e-07 30.9 0.1 1.8e-06 27.8 0.0 2.7 3 0 0 3 3 2 1 Vps4 C terminal oligomerisation domain AAA_22 PF13401.6 KKK17143.1 - 2.7e-05 24.4 0.5 0.00069 19.9 0.2 2.9 1 1 2 3 3 3 1 AAA domain AAA_2 PF07724.14 KKK17143.1 - 5e-05 23.5 0.0 8.3e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 KKK17143.1 - 6.9e-05 22.6 0.0 0.00012 21.8 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KKK17143.1 - 0.00084 19.3 0.0 0.0024 17.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_lid_3 PF17862.1 KKK17143.1 - 0.0015 18.3 0.2 0.0055 16.5 0.0 2.1 2 0 0 2 2 1 1 AAA+ lid domain AAA_16 PF13191.6 KKK17143.1 - 0.0015 18.9 0.4 0.0015 18.9 0.4 2.4 3 1 0 3 3 1 1 AAA ATPase domain TIP49 PF06068.13 KKK17143.1 - 0.0026 17.0 0.0 0.004 16.4 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain IstB_IS21 PF01695.17 KKK17143.1 - 0.0047 16.7 0.0 0.0081 15.9 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 KKK17143.1 - 0.0048 16.3 0.1 0.0098 15.3 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 KKK17143.1 - 0.0099 16.0 0.0 0.022 14.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 KKK17143.1 - 0.012 14.8 0.0 0.02 14.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_25 PF13481.6 KKK17143.1 - 0.03 13.9 0.1 0.22 11.1 0.0 2.4 2 1 1 3 3 3 0 AAA domain Sigma54_activat PF00158.26 KKK17143.1 - 0.041 13.6 0.0 0.38 10.4 0.0 2.4 2 1 0 2 2 2 0 Sigma-54 interaction domain AAA_14 PF13173.6 KKK17143.1 - 0.066 13.2 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KKK17143.1 - 0.089 12.3 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 KKK17143.1 - 0.095 12.4 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KKK17143.1 - 0.096 12.6 0.0 0.25 11.2 0.0 1.7 1 0 0 1 1 1 0 NACHT domain AAA_18 PF13238.6 KKK17143.1 - 0.13 12.8 0.0 0.37 11.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 KKK17143.1 - 0.26 10.7 0.0 0.5 9.8 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_28 PF13521.6 KKK17143.1 - 0.4 10.9 1.7 0.69 10.1 0.1 2.2 3 0 0 3 3 3 0 AAA domain ENTH PF01417.20 KKK17144.1 - 2.8e-43 146.9 0.0 5.1e-43 146.1 0.0 1.5 1 0 0 1 1 1 1 ENTH domain DUF1720 PF08226.11 KKK17144.1 - 6.4e-05 23.3 27.5 6.4e-05 23.3 27.5 4.8 1 1 2 3 3 3 2 Domain of unknown function (DUF1720) UIM PF02809.20 KKK17144.1 - 0.0011 18.7 8.1 0.039 13.9 2.6 2.6 2 0 0 2 2 2 2 Ubiquitin interaction motif ANTH PF07651.16 KKK17144.1 - 0.018 14.1 0.0 0.029 13.4 0.0 1.3 1 0 0 1 1 1 0 ANTH domain DUF4264 PF14084.6 KKK17144.1 - 0.1 12.3 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4264) Mito_carr PF00153.27 KKK17145.1 - 4.3e-64 212.5 5.8 1.8e-22 79.0 0.2 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein RmlD_sub_bind PF04321.17 KKK17154.1 - 2.4e-54 184.4 0.0 3e-54 184.1 0.0 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 KKK17154.1 - 3e-20 72.7 0.0 4e-20 72.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KKK17154.1 - 2.2e-09 36.9 0.2 2.1e-07 30.4 0.0 2.7 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 KKK17154.1 - 3.1e-09 36.4 0.1 1.5e-07 30.9 0.0 2.2 2 0 0 2 2 2 1 Male sterility protein 3Beta_HSD PF01073.19 KKK17154.1 - 8.3e-09 34.8 0.0 5.1e-08 32.3 0.0 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KKK17154.1 - 2.3e-08 33.8 0.0 5.8e-08 32.5 0.0 1.6 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase KR PF08659.10 KKK17154.1 - 0.0082 16.1 0.2 7.1 6.5 0.2 2.9 2 1 1 3 3 3 2 KR domain PH PF00169.29 KKK17155.1 - 0.00083 19.8 1.1 0.0018 18.8 1.1 1.5 1 0 0 1 1 1 1 PH domain Pkinase PF00069.25 KKK17156.1 - 1.5e-23 83.5 0.0 1.8e-23 83.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK17156.1 - 1.3e-05 24.6 0.0 2.7e-05 23.6 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KKK17156.1 - 0.013 14.3 0.0 0.015 14.1 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase FAD-oxidase_C PF02913.19 KKK17157.1 - 2.6e-61 207.4 0.0 3.5e-61 207.0 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 KKK17157.1 - 3.7e-37 127.1 0.5 6.5e-37 126.4 0.5 1.4 1 0 0 1 1 1 1 FAD binding domain Tmemb_14 PF03647.13 KKK17160.1 - 1.9e-20 73.4 9.4 2.7e-20 72.9 9.4 1.3 1 0 0 1 1 1 1 Transmembrane proteins 14C MFS_1 PF07690.16 KKK17161.1 - 1.2e-30 106.7 35.3 8.3e-30 103.9 14.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KKK17161.1 - 4.1e-09 35.8 4.5 4.1e-09 35.8 4.5 3.1 2 2 1 3 3 3 1 Sugar (and other) transporter SurE PF01975.17 KKK17162.1 - 3e-50 170.7 0.0 4e-50 170.3 0.0 1.2 1 0 0 1 1 1 1 Survival protein SurE Zn_clus PF00172.18 KKK17163.1 - 0.0018 18.4 10.2 0.0036 17.4 10.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NUC153 PF08159.12 KKK17163.1 - 0.16 11.8 2.9 1.8 8.4 0.2 2.6 2 0 0 2 2 2 0 NUC153 domain SRP68 PF16969.5 KKK17164.1 - 1.1e-192 642.0 0.1 1.3e-192 641.8 0.1 1.0 1 0 0 1 1 1 1 RNA-binding signal recognition particle 68 CCDC53 PF10152.9 KKK17164.1 - 0.12 12.8 0.3 0.44 11.0 0.3 1.9 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex SEN1_N PF12726.7 KKK17164.1 - 0.24 9.6 0.9 0.37 8.9 0.1 1.6 2 0 0 2 2 2 0 SEN1 N terminal Ribosomal_60s PF00428.19 KKK17164.1 - 6.5 7.4 18.3 0.11 13.1 6.2 2.9 3 0 0 3 3 3 0 60s Acidic ribosomal protein PPR_2 PF13041.6 KKK17165.1 - 2.1e-14 53.5 10.7 2.3e-08 34.1 0.3 7.0 7 1 2 9 9 9 4 PPR repeat family PPR PF01535.20 KKK17165.1 - 1e-13 50.5 4.5 0.0095 16.1 0.2 8.8 9 0 0 9 9 9 2 PPR repeat PPR_3 PF13812.6 KKK17165.1 - 6.4e-11 42.2 2.6 0.00018 21.5 0.0 5.7 5 1 3 8 8 8 3 Pentatricopeptide repeat domain PPR_long PF17177.4 KKK17165.1 - 1.7e-07 30.9 0.1 1.4e-06 27.9 0.0 2.5 2 1 1 3 3 3 1 Pentacotripeptide-repeat region of PRORP TPR_14 PF13428.6 KKK17165.1 - 0.00035 21.1 8.6 12 7.1 0.1 7.5 7 1 1 8 8 8 1 Tetratricopeptide repeat PPR_1 PF12854.7 KKK17165.1 - 0.015 15.0 0.2 34 4.3 0.0 4.9 5 0 0 5 5 5 0 PPR repeat Wzy_C_2 PF11846.8 KKK17165.1 - 0.13 12.2 0.2 0.52 10.2 0.1 2.1 2 0 0 2 2 2 0 Virulence factor membrane-bound polymerase, C-terminal TPR_6 PF13174.6 KKK17165.1 - 0.3 11.8 1.3 47 4.9 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat MCM PF00493.23 KKK17166.1 - 1.9e-96 321.5 0.1 3.2e-96 320.7 0.1 1.4 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KKK17166.1 - 2.4e-31 108.2 0.0 4.5e-31 107.3 0.0 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KKK17166.1 - 3.5e-23 81.8 1.9 9.7e-23 80.4 1.9 1.8 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KKK17166.1 - 1.5e-12 48.0 0.0 6e-12 46.1 0.0 2.1 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.21 KKK17166.1 - 5.1e-06 26.0 0.0 5e-05 22.8 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 KKK17166.1 - 0.0053 16.6 0.0 0.012 15.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Spo7 PF03907.13 KKK17167.1 - 2.7e-89 298.4 0.0 3.8e-89 298.0 0.0 1.2 1 0 0 1 1 1 1 Spo7-like protein Abhydrolase_1 PF00561.20 KKK17168.1 - 3e-21 76.2 0.0 5.8e-20 72.0 0.0 2.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KKK17168.1 - 2.6e-17 62.9 0.0 3e-16 59.4 0.0 2.5 3 0 0 3 3 3 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KKK17168.1 - 8.1e-16 59.3 2.7 6.4e-14 53.1 2.7 2.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF915 PF06028.11 KKK17168.1 - 2e-06 27.4 0.0 3.4e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Esterase PF00756.20 KKK17168.1 - 8.4e-06 25.6 0.0 1.9e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Putative esterase PGAP1 PF07819.13 KKK17168.1 - 0.0025 17.6 0.0 0.027 14.2 0.0 2.1 2 0 0 2 2 2 1 PGAP1-like protein Chlorophyllase2 PF12740.7 KKK17168.1 - 0.0053 15.7 0.0 0.0088 15.0 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_2 PF02230.16 KKK17168.1 - 0.031 14.1 0.0 0.47 10.2 0.0 2.4 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase LIDHydrolase PF10230.9 KKK17168.1 - 0.044 13.3 0.0 0.073 12.6 0.0 1.3 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Thioesterase PF00975.20 KKK17168.1 - 0.048 13.8 0.1 0.13 12.3 0.1 1.8 1 1 0 1 1 1 0 Thioesterase domain Abhydrolase_3 PF07859.13 KKK17168.1 - 0.058 13.2 0.1 0.17 11.7 0.0 1.8 2 0 0 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_5 PF12695.7 KKK17168.1 - 0.077 12.8 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family HPIP PF15226.6 KKK17169.1 - 0.016 15.6 2.7 0.016 15.6 2.7 2.1 3 0 0 3 3 3 0 HCF-1 beta-propeller-interacting protein family TatD_DNase PF01026.21 KKK17170.1 - 3.9e-33 114.9 0.0 7.4e-33 114.0 0.0 1.4 1 1 0 1 1 1 1 TatD related DNase Fungal_trans PF04082.18 KKK17171.1 - 1.9e-18 66.5 0.1 1.8e-17 63.2 0.0 2.4 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK17171.1 - 6.4e-10 39.0 10.2 1e-09 38.4 10.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CBFD_NFYB_HMF PF00808.23 KKK17172.1 - 2.9e-29 101.1 1.0 4.1e-29 100.6 1.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KKK17172.1 - 1.2e-07 32.1 0.5 1.8e-07 31.6 0.5 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.16 KKK17172.1 - 0.00091 19.2 0.0 0.0013 18.7 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Bromo_TP PF07524.13 KKK17172.1 - 0.0016 18.4 0.1 0.0029 17.6 0.1 1.4 1 0 0 1 1 1 1 Bromodomain associated CENP-T_C PF15511.6 KKK17172.1 - 0.0053 16.9 0.0 0.0074 16.4 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TFIID_20kDa PF03847.13 KKK17172.1 - 0.059 13.9 0.0 0.11 13.0 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A RTC4 PF14474.6 KKK17173.1 - 8.1e-33 113.2 0.0 1.7e-32 112.1 0.0 1.5 1 0 0 1 1 1 1 RTC4-like domain Rad54_N PF08658.10 KKK17173.1 - 0.035 14.3 3.4 0.05 13.8 1.6 2.2 1 1 1 2 2 2 0 Rad54 N terminal zf-MIZ PF02891.20 KKK17173.1 - 0.087 12.6 0.9 0.15 11.8 0.9 1.4 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger Menin PF05053.13 KKK17173.1 - 7.3 4.8 7.3 11 4.3 7.3 1.3 1 0 0 1 1 1 0 Menin DUF726 PF05277.12 KKK17174.1 - 3.6e-129 430.6 2.0 5.2e-129 430.1 2.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Abhydrolase_8 PF06259.12 KKK17174.1 - 0.054 13.1 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase zf-C2H2_4 PF13894.6 KKK17175.1 - 1e-06 29.1 2.1 0.013 16.3 0.1 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KKK17175.1 - 0.00022 21.5 2.8 0.011 16.2 0.1 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type HDV_ag PF01517.18 KKK17175.1 - 0.013 15.3 0.1 0.037 13.8 0.1 1.7 1 0 0 1 1 1 0 Hepatitis delta virus delta antigen zf-C2H2_11 PF16622.5 KKK17175.1 - 0.12 12.2 1.4 0.25 11.2 1.4 1.5 1 0 0 1 1 1 0 zinc-finger C2H2-type Ima1_N PF09779.9 KKK17175.1 - 0.13 13.1 0.5 0.28 12.0 0.1 1.8 2 0 0 2 2 2 0 Ima1 N-terminal domain Fungal_trans PF04082.18 KKK17177.1 - 1.6e-19 70.0 0.3 3.2e-19 69.0 0.0 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK17177.1 - 1.8e-10 40.8 11.1 3.6e-10 39.8 11.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DAD PF02109.16 KKK17178.1 - 4.9e-24 84.7 0.2 9.3e-24 83.8 0.2 1.4 1 1 0 1 1 1 1 DAD family Fungal_trans PF04082.18 KKK17179.1 - 0.00019 20.6 0.0 0.00035 19.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK17179.1 - 0.00069 19.7 11.7 0.0012 18.9 11.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3287 PF11690.8 KKK17179.1 - 0.16 11.7 0.6 0.53 10.0 0.6 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3287) ATF7IP_BD PF16788.5 KKK17179.1 - 1.1 9.3 4.4 2 8.5 4.4 1.3 1 0 0 1 1 1 0 ATF-interacting protein binding domain LicD PF04991.13 KKK17180.1 - 4.8e-08 33.4 0.8 0.00012 22.3 0.5 2.2 1 1 1 2 2 2 2 LicD family HA2 PF04408.23 KKK17181.1 - 3.9e-20 72.1 2.2 1e-19 70.8 0.0 2.7 3 0 0 3 3 3 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KKK17181.1 - 1.2e-16 60.8 0.0 5.1e-16 58.8 0.0 2.1 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KKK17181.1 - 9.5e-16 58.1 0.0 2.3e-15 56.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KKK17181.1 - 1.9e-06 27.8 0.0 4.5e-06 26.6 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KKK17181.1 - 1.6e-05 25.2 0.0 4.4e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 KKK17181.1 - 7.9e-05 22.0 0.0 0.00014 21.2 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) T2SSE PF00437.20 KKK17181.1 - 0.001 18.2 0.1 0.0088 15.1 0.0 2.4 3 0 0 3 3 3 1 Type II/IV secretion system protein AAA_30 PF13604.6 KKK17181.1 - 0.0014 18.4 0.0 0.0032 17.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 KKK17181.1 - 0.0025 17.5 0.2 0.008 15.8 0.2 1.9 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_19 PF13245.6 KKK17181.1 - 0.0033 17.8 0.1 0.011 16.0 0.1 1.9 2 0 0 2 2 2 1 AAA domain ATPase PF06745.13 KKK17181.1 - 0.0065 15.8 0.0 0.013 14.9 0.0 1.4 1 0 0 1 1 1 1 KaiC AAA_24 PF13479.6 KKK17181.1 - 0.013 15.3 0.0 0.024 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KKK17181.1 - 0.014 15.4 0.2 0.087 12.9 0.2 2.2 1 1 0 1 1 1 0 AAA domain Flavi_DEAD PF07652.14 KKK17181.1 - 0.015 15.3 0.0 0.028 14.4 0.0 1.4 1 0 0 1 1 1 0 Flavivirus DEAD domain ResIII PF04851.15 KKK17181.1 - 0.022 14.7 0.0 7.2 6.6 0.0 2.5 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_33 PF13671.6 KKK17181.1 - 0.054 13.7 0.8 0.37 10.9 0.0 2.6 2 1 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KKK17181.1 - 0.1 13.1 0.1 0.36 11.3 0.0 2.0 2 0 0 2 2 1 0 ABC transporter AAA_7 PF12775.7 KKK17181.1 - 0.12 11.8 0.0 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_16 PF13191.6 KKK17181.1 - 0.14 12.6 0.0 0.35 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain cobW PF02492.19 KKK17181.1 - 0.18 11.4 0.2 1.5 8.4 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF5401 PF17380.2 KKK17181.1 - 7.4 4.5 13.9 0.77 7.8 8.5 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5401) Prefoldin_2 PF01920.20 KKK17182.1 - 2.5e-26 91.7 8.1 3.4e-26 91.3 8.1 1.1 1 0 0 1 1 1 1 Prefoldin subunit ATPase PF06745.13 KKK17182.1 - 0.0037 16.6 0.5 0.14 11.5 0.1 2.0 1 1 1 2 2 2 1 KaiC Tho2 PF11262.8 KKK17182.1 - 0.019 14.2 1.0 0.03 13.5 1.0 1.4 1 1 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 BRE PF06113.12 KKK17182.1 - 0.036 12.9 0.0 0.052 12.4 0.0 1.3 1 0 0 1 1 1 0 Brain and reproductive organ-expressed protein (BRE) ATP-synt_D PF01813.17 KKK17182.1 - 0.05 13.4 1.8 5.1 6.9 0.2 2.1 2 0 0 2 2 2 0 ATP synthase subunit D Prefoldin PF02996.17 KKK17182.1 - 0.064 13.2 7.2 0.57 10.1 0.2 2.2 1 1 0 2 2 2 0 Prefoldin subunit Troponin PF00992.20 KKK17182.1 - 0.086 13.1 4.7 2 8.7 0.1 2.1 2 0 0 2 2 2 0 Troponin p25-alpha PF05517.12 KKK17182.1 - 0.16 12.1 1.5 1.7 8.8 0.2 2.0 2 0 0 2 2 2 0 p25-alpha OmpH PF03938.14 KKK17182.1 - 0.35 11.2 10.1 4 7.8 5.4 2.1 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) ZnuA PF01297.17 KKK17182.1 - 0.47 9.8 3.2 1 8.7 1.4 1.9 2 0 0 2 2 2 0 Zinc-uptake complex component A periplasmic RF-1 PF00472.20 KKK17182.1 - 1 9.3 5.8 0.68 9.9 1.2 2.1 2 0 0 2 2 2 0 RF-1 domain TFR_dimer PF04253.15 KKK17183.1 - 1.6e-30 105.7 0.0 2.6e-30 105.0 0.0 1.3 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 KKK17183.1 - 1.3e-18 67.4 0.0 2.1e-18 66.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 KKK17183.1 - 1e-10 41.5 0.2 3.1e-10 40.0 0.0 1.8 2 0 0 2 2 2 1 PA domain CMD PF02627.20 KKK17183.1 - 6.4e-05 22.9 0.0 0.00021 21.3 0.0 1.9 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family Nicastrin PF05450.15 KKK17183.1 - 0.0072 15.8 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 Nicastrin DUF5427 PF10310.9 KKK17184.1 - 2e-163 544.6 0.2 2.6e-163 544.3 0.2 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5427) Flu_M1_C PF08289.11 KKK17184.1 - 0.021 15.0 3.1 0.22 11.8 1.3 2.5 2 0 0 2 2 2 0 Influenza Matrix protein (M1) C-terminal domain SARAF PF06682.12 KKK17184.1 - 1.3 8.6 5.3 2.2 7.8 5.3 1.3 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis RRM_1 PF00076.22 KKK17185.1 - 0.00027 20.7 0.0 0.00051 19.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2985 PF11204.8 KKK17186.1 - 4.7e-22 77.9 3.6 8.6e-22 77.1 3.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) Peptidase_S49_N PF08496.10 KKK17186.1 - 0.094 12.8 0.7 0.19 11.8 0.7 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal VASt PF16016.5 KKK17187.1 - 8.3e-36 123.7 0.0 1.4e-35 123.0 0.0 1.4 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 KKK17187.1 - 1.7e-22 79.5 0.0 3e-22 78.7 0.0 1.4 1 0 0 1 1 1 1 GRAM domain Rab_eff_C PF04698.12 KKK17234.1 - 0.014 13.8 0.2 0.016 13.6 0.2 1.0 1 0 0 1 1 1 0 Rab effector MyRIP/melanophilin C-terminus Ntox28 PF15605.6 KKK17234.1 - 0.029 14.6 0.7 0.037 14.3 0.7 1.2 1 0 0 1 1 1 0 Bacterial toxin 28 Osmo_CC PF08946.10 KKK17234.1 - 0.039 14.2 3.7 0.95 9.8 0.1 2.4 1 1 1 2 2 2 0 Osmosensory transporter coiled coil SMC_N PF02463.19 KKK17235.1 - 5.5e-23 81.5 0.0 1.3e-22 80.3 0.0 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KKK17235.1 - 5.7e-09 36.8 78.9 6.5e-07 30.1 34.1 5.4 2 2 0 2 2 1 1 AAA domain AAA_21 PF13304.6 KKK17235.1 - 2.9e-06 27.3 4.1 0.034 13.9 0.1 3.2 3 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KKK17235.1 - 0.0035 17.0 0.0 0.007 16.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_13 PF13166.6 KKK17235.1 - 0.0085 14.8 71.6 0.0072 15.0 17.8 5.0 3 2 2 5 5 5 4 AAA domain ABC_tran PF00005.27 KKK17235.1 - 0.076 13.5 0.0 0.076 13.5 0.0 4.4 3 1 0 3 3 2 0 ABC transporter AAA_25 PF13481.6 KKK17235.1 - 0.11 12.0 4.1 0.29 10.7 0.0 3.3 3 0 0 3 3 3 0 AAA domain PSP1 PF04468.12 KKK17235.1 - 0.37 11.1 0.1 0.37 11.1 0.1 3.6 4 0 0 4 4 3 0 PSP1 C-terminal conserved region AAA PF00004.29 KKK17235.1 - 0.91 10.0 6.5 1.1 9.7 0.0 3.6 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Tropomyosin_1 PF12718.7 KKK17235.1 - 2.7 8.1 89.3 0.062 13.5 17.5 6.6 2 2 4 6 6 5 0 Tropomyosin like SMBP PF16785.5 KKK17235.1 - 6.5 7.0 13.5 1.4 9.2 1.3 3.7 3 0 0 3 3 3 0 Small metal-binding protein FMN_dh PF01070.18 KKK17236.1 - 3.6e-123 411.0 0.0 4.1e-123 410.9 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase NMO PF03060.15 KKK17236.1 - 4.2e-06 26.4 0.5 6.1e-06 25.9 0.5 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase ThiG PF05690.14 KKK17236.1 - 5.2e-05 22.7 0.1 0.0091 15.3 0.2 2.4 3 0 0 3 3 3 2 Thiazole biosynthesis protein ThiG IMPDH PF00478.25 KKK17236.1 - 0.00097 18.2 0.5 0.0015 17.6 0.5 1.4 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 KKK17236.1 - 0.0023 17.2 0.1 0.0023 17.2 0.1 1.5 2 0 0 2 2 2 1 Conserved region in glutamate synthase His_biosynth PF00977.21 KKK17236.1 - 0.045 13.2 0.2 0.66 9.4 0.1 2.5 2 1 0 3 3 3 0 Histidine biosynthesis protein Lipase_3 PF01764.25 KKK17237.1 - 3.7e-16 59.3 0.1 3e-14 53.1 0.1 2.6 1 1 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 KKK17237.1 - 0.012 16.3 0.1 0.027 15.1 0.1 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KKK17237.1 - 0.067 12.4 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 MFS_1 PF07690.16 KKK17239.1 - 1.2e-34 119.8 27.9 6.7e-34 117.4 28.4 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF3218 PF11508.8 KKK17239.1 - 0.17 11.4 0.5 0.31 10.5 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3218) Phage_holin_2_1 PF04971.12 KKK17239.1 - 1 9.4 12.4 0.91 9.6 0.7 3.9 3 1 0 3 3 3 0 Bacteriophage P21 holin S DUF4131 PF13567.6 KKK17239.1 - 2.1 8.0 12.7 6.3 6.4 2.0 3.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) NAC PF01849.18 KKK17240.1 - 7.2e-24 83.5 0.3 1.3e-23 82.7 0.3 1.4 1 0 0 1 1 1 1 NAC domain MAGI_u1 PF16663.5 KKK17240.1 - 0.02 15.0 0.0 0.041 14.0 0.0 1.5 1 0 0 1 1 1 0 Unstructured region on MAGI zf-C2H2 PF00096.26 KKK17241.1 - 5.8e-07 29.6 15.6 0.0041 17.5 3.2 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KKK17241.1 - 0.00017 21.9 12.5 0.00075 19.8 1.6 3.8 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KKK17241.1 - 0.0052 17.5 14.1 0.53 11.3 2.7 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger SOCS PF12610.8 KKK17241.1 - 0.25 11.8 4.8 9.9 6.6 0.4 2.8 2 1 0 2 2 2 0 Suppressor of cytokine signalling zf-met PF12874.7 KKK17241.1 - 0.44 11.0 4.5 1.1 9.8 2.2 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KKK17241.1 - 1.8 8.6 6.6 0.25 11.4 2.0 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger PALP PF00291.25 KKK17242.1 - 3.8e-10 39.6 0.7 1.5e-08 34.5 0.0 2.0 1 1 1 2 2 2 2 Pyridoxal-phosphate dependent enzyme Nup160 PF11715.8 KKK17244.1 - 0.11 11.1 0.0 0.22 10.1 0.0 1.4 1 0 0 1 1 1 0 Nucleoporin Nup120/160 Fungal_trans PF04082.18 KKK17245.1 - 5.4e-06 25.6 0.5 1.1e-05 24.6 0.5 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain p450 PF00067.22 KKK17246.1 - 0.0042 15.9 0.0 0.0063 15.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_3 PF01494.19 KKK17247.1 - 4.8e-30 105.0 0.0 4.8e-29 101.7 0.0 1.9 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KKK17247.1 - 9.7e-08 31.6 0.2 0.0004 19.7 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KKK17247.1 - 1.1e-06 28.4 0.6 0.0015 18.2 0.2 2.2 1 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KKK17247.1 - 1.8e-05 24.9 0.0 3.9e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KKK17247.1 - 4.8e-05 22.8 0.1 0.005 16.1 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 KKK17247.1 - 8.7e-05 21.7 0.0 0.0046 16.0 0.0 2.1 2 0 0 2 2 2 1 Squalene epoxidase Trp_halogenase PF04820.14 KKK17247.1 - 0.0003 19.8 0.1 0.77 8.5 0.0 2.9 3 0 0 3 3 3 2 Tryptophan halogenase HI0933_like PF03486.14 KKK17247.1 - 0.00035 19.4 0.0 0.019 13.7 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.24 KKK17247.1 - 0.0014 17.8 0.0 0.0029 16.7 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 KKK17247.1 - 0.0015 17.6 0.4 0.035 13.2 0.0 2.5 3 0 0 3 3 3 1 Lycopene cyclase protein NAD_binding_9 PF13454.6 KKK17247.1 - 0.023 14.7 0.3 0.094 12.7 0.1 2.0 2 0 0 2 2 2 0 FAD-NAD(P)-binding Thi4 PF01946.17 KKK17247.1 - 0.067 12.4 0.1 0.11 11.7 0.1 1.3 1 0 0 1 1 1 0 Thi4 family Cu_bind_CorA PF18252.1 KKK17247.1 - 0.075 12.7 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Copper(I)-binding protein CorA Pyr_redox PF00070.27 KKK17247.1 - 0.14 12.7 0.0 15 6.2 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GST_C_2 PF13410.6 KKK17249.1 - 4e-08 33.2 0.2 1.4e-07 31.4 0.2 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KKK17249.1 - 1.2e-05 25.6 0.0 2.6e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KKK17249.1 - 2.6e-05 24.6 0.0 4.6e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KKK17249.1 - 8.4e-05 22.7 0.0 0.00014 22.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 KKK17249.1 - 0.0093 16.7 0.0 0.021 15.5 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase N-terminal domain Cation_efflux PF01545.21 KKK17250.1 - 1.4e-49 168.5 7.4 1.9e-49 168.1 7.4 1.1 1 0 0 1 1 1 1 Cation efflux family BPD_transp_2 PF02653.16 KKK17250.1 - 0.00049 19.4 0.0 0.00049 19.4 0.0 1.8 2 1 0 2 2 2 1 Branched-chain amino acid transport system / permease component APH PF01636.23 KKK17251.1 - 0.0019 18.2 0.0 0.0019 18.2 0.0 3.0 2 1 0 2 2 2 1 Phosphotransferase enzyme family HSDR_N_2 PF13588.6 KKK17251.1 - 0.0059 16.6 0.1 0.27 11.2 0.1 2.5 2 0 0 2 2 2 1 Type I restriction enzyme R protein N terminus (HSDR_N) SpoIIIAH PF12685.7 KKK17251.1 - 1.6 8.5 10.3 2.9 7.7 2.6 2.3 2 0 0 2 2 2 0 SpoIIIAH-like protein CDC45 PF02724.14 KKK17251.1 - 3.1 6.0 23.7 0.91 7.7 10.8 2.2 2 0 0 2 2 2 0 CDC45-like protein DDHD PF02862.17 KKK17251.1 - 4.4 7.4 15.8 2.9 8.0 0.3 2.4 2 1 0 2 2 2 0 DDHD domain RNA_pol_Rpc4 PF05132.14 KKK17251.1 - 4.4 7.7 16.4 3.4 8.1 0.3 2.4 2 0 0 2 2 2 0 RNA polymerase III RPC4 RP-C_C PF11800.8 KKK17251.1 - 4.6 7.3 21.1 4.4 7.3 9.4 2.4 2 0 0 2 2 2 0 Replication protein C C-terminal region AAR2 PF05282.11 KKK17251.1 - 6 6.2 8.5 9.1 5.6 0.6 2.3 2 0 0 2 2 2 0 AAR2 protein Glyco_hydro_76 PF03663.14 KKK17252.1 - 2.6e-140 468.1 22.5 3.2e-140 467.8 22.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 TPR_12 PF13424.6 KKK17253.1 - 2e-09 37.6 29.7 0.00082 19.6 0.1 9.1 10 0 0 10 10 10 4 Tetratricopeptide repeat AAA_22 PF13401.6 KKK17253.1 - 1.5e-06 28.5 0.2 0.0024 18.1 0.0 3.3 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 KKK17253.1 - 6.4e-06 26.2 0.0 2.8e-05 24.1 0.0 2.2 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KKK17253.1 - 8.8e-05 22.9 0.2 0.0012 19.3 0.0 3.2 2 0 0 2 2 2 1 AAA ATPase domain TPR_19 PF14559.6 KKK17253.1 - 0.043 14.3 11.1 0.33 11.5 0.1 6.3 6 1 1 7 7 7 0 Tetratricopeptide repeat NB-ARC PF00931.22 KKK17253.1 - 0.088 12.0 0.0 0.21 10.7 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain TPR_14 PF13428.6 KKK17253.1 - 0.11 13.4 21.2 6.1 7.9 0.0 8.0 9 0 0 9 9 9 0 Tetratricopeptide repeat GCN5L1 PF06320.13 KKK17253.1 - 8 6.6 6.9 0.73 10.0 0.0 2.9 3 0 0 3 3 3 0 GCN5-like protein 1 (GCN5L1) Abhydrolase_3 PF07859.13 KKK17254.1 - 1.2e-53 182.2 0.0 1.5e-53 181.8 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KKK17254.1 - 7.1e-06 25.1 0.0 9.3e-06 24.7 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Chlorophyllase2 PF12740.7 KKK17254.1 - 7.5e-06 25.0 0.0 1.3e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme LIDHydrolase PF10230.9 KKK17254.1 - 0.00025 20.7 0.0 0.00035 20.2 0.0 1.2 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase COesterase PF00135.28 KKK17254.1 - 0.0013 17.7 0.1 0.014 14.3 0.0 2.0 2 0 0 2 2 2 1 Carboxylesterase family Esterase PF00756.20 KKK17254.1 - 0.0071 16.0 0.0 0.04 13.6 0.0 1.9 1 1 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.8 KKK17254.1 - 0.026 13.8 0.0 0.093 12.0 0.0 1.7 1 1 1 2 2 2 0 Serine aminopeptidase, S33 Glyco_transf_28 PF03033.20 KKK17255.1 - 6e-17 62.0 0.7 2.6e-13 50.2 0.1 2.3 2 0 0 2 2 2 2 Glycosyltransferase family 28 N-terminal domain ATG_C PF09333.11 KKK17255.1 - 0.0073 16.6 0.0 0.025 14.9 0.0 1.8 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain Pyr_redox_2 PF07992.14 KKK17256.1 - 1.8e-32 112.8 0.0 2.3e-32 112.4 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KKK17256.1 - 2.6e-16 59.9 0.0 3.4e-12 46.7 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KKK17256.1 - 6.5e-10 38.8 0.0 3.7e-09 36.3 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KKK17256.1 - 9.1e-08 32.1 0.0 0.069 12.7 0.1 3.3 3 0 0 3 3 3 2 FAD dependent oxidoreductase K_oxygenase PF13434.6 KKK17256.1 - 8.3e-07 28.5 0.1 2.4e-06 26.9 0.0 1.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_7 PF13241.6 KKK17256.1 - 4e-05 24.0 0.0 0.0079 16.6 0.0 2.4 2 0 0 2 2 2 1 Putative NAD(P)-binding NAD_binding_9 PF13454.6 KKK17256.1 - 8.3e-05 22.6 0.1 11 6.0 0.0 4.1 4 0 0 4 4 4 1 FAD-NAD(P)-binding TrkA_N PF02254.18 KKK17256.1 - 0.00011 22.5 0.0 0.16 12.2 0.0 3.1 4 0 0 4 4 4 2 TrkA-N domain NAD_binding_8 PF13450.6 KKK17256.1 - 0.00017 21.8 0.0 0.71 10.2 0.0 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 KKK17256.1 - 0.00032 19.7 0.0 0.29 9.9 0.0 2.2 2 0 0 2 2 2 2 Tryptophan halogenase DUF1188 PF06690.11 KKK17256.1 - 0.0019 17.8 0.0 1.4 8.4 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1188) THF_DHG_CYH_C PF02882.19 KKK17256.1 - 0.016 14.5 0.4 0.36 10.1 0.0 2.6 3 0 0 3 3 3 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Lycopene_cycl PF05834.12 KKK17256.1 - 0.09 11.8 0.0 0.44 9.5 0.0 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein Sacchrp_dh_NADP PF03435.18 KKK17256.1 - 0.15 12.3 0.0 24 5.2 0.0 2.3 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain AdoHcyase_NAD PF00670.21 KKK17256.1 - 0.17 11.9 0.1 7.9 6.5 0.0 2.5 3 0 0 3 3 3 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Aminotran_4 PF01063.19 KKK17257.1 - 7.6e-25 88.1 0.0 1.1e-24 87.5 0.0 1.2 1 0 0 1 1 1 1 Amino-transferase class IV FAD_binding_7 PF03441.14 KKK17258.1 - 2.8e-82 275.1 0.7 4.7e-82 274.4 0.7 1.4 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 KKK17258.1 - 4.6e-41 140.6 0.2 7.7e-41 139.8 0.2 1.3 1 0 0 1 1 1 1 DNA photolyase Beta-lactamase PF00144.24 KKK17258.1 - 0.13 11.5 0.2 1.6 7.9 0.0 2.1 2 0 0 2 2 2 0 Beta-lactamase Fungal_trans PF04082.18 KKK17259.1 - 9.8e-20 70.7 0.1 1.7e-18 66.6 0.1 2.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK17259.1 - 2.3e-09 37.2 11.8 4.3e-09 36.3 11.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mucin PF01456.17 KKK17259.1 - 0.0067 16.4 25.8 0.017 15.1 25.8 1.6 1 0 0 1 1 1 1 Mucin-like glycoprotein FSA_C PF10479.9 KKK17259.1 - 1.4 6.9 12.2 2.1 6.4 12.2 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Zn_clus PF00172.18 KKK17260.1 - 2.1e-05 24.6 13.3 2.1e-05 24.6 13.3 2.3 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2054 PF10218.9 KKK17260.1 - 0.11 12.6 6.8 0.17 12.0 4.9 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2054) Glyco_hydro_16 PF00722.21 KKK17261.1 - 0.0099 15.4 0.3 0.051 13.0 0.1 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 Peptidase_C48 PF02902.19 KKK17262.1 - 2e-25 89.9 0.0 3.8e-25 89.0 0.0 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain LPP PF04728.13 KKK17263.1 - 1.1e-05 25.7 5.3 0.012 16.0 0.7 3.6 2 1 1 3 3 3 1 Lipoprotein leucine-zipper DUF1664 PF07889.12 KKK17263.1 - 0.0003 20.8 1.9 0.0011 19.0 1.3 2.2 2 1 0 2 2 2 1 Protein of unknown function (DUF1664) DUF4618 PF15397.6 KKK17263.1 - 0.00041 19.8 2.9 0.18 11.2 0.4 2.8 1 1 2 3 3 3 2 Domain of unknown function (DUF4618) HMMR_N PF15905.5 KKK17263.1 - 0.0006 19.4 1.4 0.0012 18.4 0.8 1.7 1 1 1 2 2 2 1 Hyaluronan mediated motility receptor N-terminal CENP-F_leu_zip PF10473.9 KKK17263.1 - 0.001 19.1 5.2 0.046 13.7 0.5 2.8 2 1 1 3 3 3 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF641 PF04859.12 KKK17263.1 - 0.0012 19.2 1.9 0.1 13.0 0.3 2.4 1 1 1 2 2 2 1 Plant protein of unknown function (DUF641) Spc7 PF08317.11 KKK17263.1 - 0.0017 17.3 1.6 0.0027 16.7 1.6 1.4 1 0 0 1 1 1 1 Spc7 kinetochore protein AAA_13 PF13166.6 KKK17263.1 - 0.003 16.3 0.2 0.0061 15.3 0.1 1.4 1 1 0 1 1 1 1 AAA domain ATG16 PF08614.11 KKK17263.1 - 0.0063 16.8 2.8 0.0063 16.8 2.8 1.9 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) TSC22 PF01166.18 KKK17263.1 - 0.0067 16.7 0.1 0.37 11.1 0.0 2.7 1 1 1 2 2 2 1 TSC-22/dip/bun family AIP3 PF03915.13 KKK17263.1 - 0.008 15.3 2.6 0.015 14.4 2.6 1.5 1 0 0 1 1 1 1 Actin interacting protein 3 EzrA PF06160.12 KKK17263.1 - 0.019 13.1 0.1 0.037 12.2 0.1 1.3 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA Mto2_bdg PF12808.7 KKK17263.1 - 0.024 14.9 0.3 0.38 11.1 0.0 2.8 3 0 0 3 3 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region Plasmid_RAQPRD PF09686.10 KKK17263.1 - 0.029 14.6 0.8 1.9 8.7 0.1 2.7 1 1 0 2 2 2 0 Plasmid protein of unknown function (Plasmid_RAQPRD) Atg14 PF10186.9 KKK17263.1 - 0.044 12.9 3.8 0.024 13.7 0.7 1.9 1 1 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Prominin PF05478.11 KKK17263.1 - 0.045 11.7 3.5 0.095 10.6 3.3 1.4 1 1 0 1 1 1 0 Prominin COG7 PF10191.9 KKK17263.1 - 0.055 11.7 1.7 0.37 9.0 1.2 1.9 1 1 1 2 2 2 0 Golgi complex component 7 (COG7) NPV_P10 PF05531.12 KKK17263.1 - 0.064 13.7 5.2 0.19 12.2 0.9 3.1 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Bacillus_HBL PF05791.11 KKK17263.1 - 0.082 12.7 0.4 0.12 12.2 0.4 1.2 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) Seryl_tRNA_N PF02403.22 KKK17263.1 - 0.088 13.0 0.2 0.19 11.9 0.2 1.6 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Fib_alpha PF08702.10 KKK17263.1 - 0.1 12.8 1.5 0.82 9.8 0.9 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Tropomyosin_1 PF12718.7 KKK17263.1 - 0.11 12.7 0.1 0.34 11.0 0.1 1.9 1 1 0 1 1 1 0 Tropomyosin like CLZ PF16526.5 KKK17263.1 - 0.11 12.9 4.6 19 5.7 0.1 3.6 1 1 2 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels KASH_CCD PF14662.6 KKK17263.1 - 0.14 12.0 3.4 0.33 10.7 0.8 2.1 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH ADIP PF11559.8 KKK17263.1 - 0.15 12.1 3.5 1.7 8.7 0.6 2.3 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Vps51 PF08700.11 KKK17263.1 - 0.18 11.9 2.1 36 4.5 0.1 3.4 2 1 1 3 3 3 0 Vps51/Vps67 DUF5082 PF16888.5 KKK17263.1 - 0.23 11.7 1.6 1.4 9.2 0.3 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) DUF1640 PF07798.11 KKK17263.1 - 0.29 11.1 4.7 44 4.1 4.5 2.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) MscS_porin PF12795.7 KKK17263.1 - 0.3 10.6 0.1 0.3 10.6 0.1 2.1 2 1 0 2 2 2 0 Mechanosensitive ion channel porin domain FlaC_arch PF05377.11 KKK17263.1 - 0.32 11.4 1.2 8 6.9 0.5 3.2 2 1 0 2 2 1 0 Flagella accessory protein C (FlaC) COG5 PF10392.9 KKK17263.1 - 0.33 11.1 9.0 0.26 11.5 1.0 3.4 1 1 3 4 4 4 0 Golgi transport complex subunit 5 Baculo_PEP_C PF04513.12 KKK17263.1 - 0.41 10.7 6.1 0.072 13.1 1.9 1.8 2 1 0 2 2 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Syntaxin_2 PF14523.6 KKK17263.1 - 0.69 10.3 4.5 0.2 12.1 1.0 1.9 2 1 0 2 2 2 0 Syntaxin-like protein Fez1 PF06818.15 KKK17263.1 - 0.72 10.3 6.3 0.3 11.5 0.5 2.4 2 1 1 3 3 2 0 Fez1 FAM76 PF16046.5 KKK17263.1 - 8.3 5.7 8.4 2.8 7.2 2.1 2.5 2 1 1 3 3 3 0 FAM76 protein PAP2 PF01569.21 KKK17264.1 - 4.6e-17 62.1 3.2 4.6e-17 62.1 3.2 2.1 2 0 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 KKK17264.1 - 0.0061 16.3 7.8 0.039 13.6 7.8 2.1 1 1 0 1 1 1 1 PAP2 superfamily Ras PF00071.22 KKK17265.1 - 1.3e-48 164.6 0.0 1.7e-48 164.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KKK17265.1 - 4.9e-21 75.2 0.0 7.9e-21 74.5 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKK17265.1 - 6.1e-05 22.5 0.0 0.0002 20.9 0.0 1.8 1 1 0 1 1 1 1 ADP-ribosylation factor family AAA_7 PF12775.7 KKK17265.1 - 0.018 14.6 0.0 0.032 13.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region SRPRB PF09439.10 KKK17265.1 - 0.039 13.4 0.0 0.062 12.7 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit adh_short PF00106.25 KKK17266.1 - 1.2e-23 83.6 0.0 1.5e-23 83.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KKK17266.1 - 1.8e-20 73.5 0.0 2.3e-20 73.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KKK17266.1 - 4.1e-06 26.8 0.0 6.8e-06 26.1 0.0 1.4 1 1 0 1 1 1 1 KR domain NmrA PF05368.13 KKK17266.1 - 0.025 14.1 0.2 0.06 12.9 0.1 1.6 2 0 0 2 2 2 0 NmrA-like family zf-HIT PF04438.16 KKK17267.1 - 2.9e-10 39.8 9.9 4.6e-10 39.2 9.9 1.3 1 0 0 1 1 1 1 HIT zinc finger SUIM_assoc PF16619.5 KKK17267.1 - 0.00078 19.5 0.9 0.0021 18.1 0.9 1.8 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 DUF4045 PF13254.6 KKK17267.1 - 2.1 7.9 10.8 2.7 7.5 8.6 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4045) Spt20 PF12090.8 KKK17267.1 - 8.9 5.8 10.5 0.48 10.0 2.4 2.1 2 0 0 2 2 2 0 Spt20 family DEP PF00610.21 KKK17268.1 - 3.4e-24 84.7 0.0 6.4e-18 64.6 0.0 3.5 3 0 0 3 3 3 3 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) RGS PF00615.19 KKK17268.1 - 2.1e-10 40.9 0.1 5.6e-10 39.5 0.1 1.7 1 0 0 1 1 1 1 Regulator of G protein signaling domain MFS_1 PF07690.16 KKK17273.1 - 5.1e-44 150.6 49.3 4.3e-43 147.6 49.3 2.5 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KKK17273.1 - 3.8e-10 38.8 23.8 7.9e-10 37.8 23.8 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KKK17273.1 - 1.5e-08 33.9 12.8 1.5e-08 33.9 12.8 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter DUF1430 PF07242.11 KKK17273.1 - 1.2 9.5 0.0 1.2 9.5 0.0 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF1430) DUF2530 PF10745.9 KKK17273.1 - 6.1 7.2 8.2 1 9.7 1.7 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF2530) Thiolase_N PF00108.23 KKK17274.1 - 7.8e-79 264.7 0.1 1.4e-78 263.9 0.1 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KKK17274.1 - 1e-37 128.5 1.0 1e-37 128.5 1.0 2.4 2 1 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KKK17274.1 - 1.2e-05 25.1 3.4 1.6e-05 24.6 2.1 1.9 2 1 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Inhibitor_I66 PF16850.5 KKK17274.1 - 0.16 11.8 0.0 4.5 7.1 0.0 2.2 2 0 0 2 2 2 0 Peptidase inhibitor I66 Peptidase_C2 PF00648.21 KKK17275.1 - 3e-50 170.9 4.9 2.4e-48 164.7 4.9 3.3 1 1 0 1 1 1 1 Calpain family cysteine protease Pkinase PF00069.25 KKK17276.1 - 7.8e-71 238.5 0.0 1.1e-70 238.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK17276.1 - 2.5e-30 105.6 0.0 3.3e-30 105.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KKK17276.1 - 0.00048 19.2 0.1 0.016 14.2 0.0 2.1 2 0 0 2 2 2 1 Haspin like kinase domain Kinase-like PF14531.6 KKK17276.1 - 0.0013 18.1 0.0 0.0023 17.3 0.0 1.4 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 KKK17276.1 - 0.0026 17.7 0.6 0.0051 16.8 0.1 1.7 2 1 0 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KKK17276.1 - 0.017 14.2 0.0 0.026 13.6 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Abhydrolase_1 PF00561.20 KKK17277.1 - 1.2e-11 44.8 0.0 4.3e-11 42.9 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KKK17277.1 - 1.7e-10 41.9 2.5 1.7e-10 41.9 2.5 2.8 1 1 2 3 3 3 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KKK17277.1 - 7.6e-07 28.6 0.0 1.4e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 KKK17277.1 - 0.00012 20.9 0.0 0.00025 19.8 0.0 1.5 1 1 0 1 1 1 1 Ndr family EthD PF07110.11 KKK17277.1 - 0.028 15.5 0.2 5.8 8.1 0.0 2.7 2 0 0 2 2 2 0 EthD domain Aldedh PF00171.22 KKK17315.1 - 5.7e-105 351.5 1.0 3.8e-102 342.2 1.0 2.1 1 1 0 1 1 1 1 Aldehyde dehydrogenase family Hexapep PF00132.24 KKK17334.1 - 8.2e-09 34.9 14.1 0.018 14.7 1.4 4.4 3 1 2 5 5 5 5 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KKK17334.1 - 2.4e-05 24.0 7.5 0.00084 19.0 0.8 3.1 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase gerPA PF10676.9 KKK17334.1 - 0.056 13.7 1.2 1.3 9.4 0.2 2.3 2 0 0 2 2 2 0 Spore germination protein gerPA/gerPF GNAT_acetyltr_2 PF13718.6 KKK17335.1 - 7.8e-98 326.4 0.0 1.3e-97 325.6 0.0 1.4 1 0 0 1 1 1 1 GNAT acetyltransferase 2 tRNA_bind_2 PF13725.6 KKK17335.1 - 3.3e-94 315.0 0.0 6.2e-94 314.1 0.0 1.5 1 0 0 1 1 1 1 Possible tRNA binding domain Helicase_RecD PF05127.14 KKK17335.1 - 8.7e-66 221.1 0.0 2.5e-65 219.7 0.0 1.8 2 0 0 2 2 2 1 Helicase DUF1726 PF08351.11 KKK17335.1 - 5.4e-34 116.0 0.0 1.5e-33 114.6 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) AAA_30 PF13604.6 KKK17335.1 - 0.00046 20.0 0.1 0.081 12.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KKK17335.1 - 0.0088 16.3 0.0 0.19 12.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain Acetyltransf_1 PF00583.25 KKK17335.1 - 0.035 14.3 0.0 0.22 11.8 0.0 2.3 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family Svs_4_5_6 PF17381.2 KKK17335.1 - 0.15 13.0 3.7 0.34 11.9 3.7 1.6 1 0 0 1 1 1 0 Seminal vesicle secretory proteins 4/5/6 Topoisom_I_N PF02919.15 KKK17336.1 - 2e-94 315.0 1.8 2e-94 315.0 1.8 3.3 3 0 0 3 3 3 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.20 KKK17336.1 - 2.1e-94 315.2 9.9 2.1e-94 315.2 9.9 2.0 2 0 0 2 2 2 1 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.6 KKK17336.1 - 1e-33 115.0 1.0 3.4e-33 113.4 1.0 2.0 1 0 0 1 1 1 1 C-terminal topoisomerase domain ATP-synt PF00231.19 KKK17337.1 - 3.6e-73 246.7 6.5 4.4e-73 246.4 6.5 1.0 1 0 0 1 1 1 1 ATP synthase DnaJ PF00226.31 KKK17338.1 - 1.4e-18 66.7 0.2 3.4e-18 65.5 0.2 1.7 1 0 0 1 1 1 1 DnaJ domain DUF3723 PF12520.8 KKK17338.1 - 0.018 13.7 0.6 0.03 13.0 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3723) Thioredoxin PF00085.20 KKK17339.1 - 3e-31 107.4 0.0 1.1e-25 89.6 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.6 KKK17339.1 - 1.2e-06 29.0 0.1 0.017 15.6 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin-like domain OST3_OST6 PF04756.13 KKK17339.1 - 5e-06 26.1 0.0 1e-05 25.0 0.0 1.5 2 0 0 2 2 2 1 OST3 / OST6 family, transporter family TraF PF13728.6 KKK17339.1 - 0.00083 19.2 0.0 0.041 13.7 0.0 2.7 2 0 0 2 2 2 1 F plasmid transfer operon protein Thioredoxin_8 PF13905.6 KKK17339.1 - 0.0067 16.7 0.0 0.95 9.8 0.0 3.5 3 2 1 4 4 4 1 Thioredoxin-like AhpC-TSA PF00578.21 KKK17339.1 - 0.0096 15.8 0.0 0.03 14.3 0.0 1.8 2 0 0 2 2 2 1 AhpC/TSA family Thioredoxin_3 PF13192.6 KKK17339.1 - 0.041 13.9 0.1 2.2 8.4 0.1 2.4 2 0 0 2 2 2 0 Thioredoxin domain QSOX_Trx1 PF18108.1 KKK17339.1 - 0.058 13.6 0.0 0.21 11.8 0.0 1.9 2 0 0 2 2 2 0 QSOX Trx-like domain Thioredoxin_7 PF13899.6 KKK17339.1 - 0.077 13.2 0.0 0.17 12.1 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin-like F-box PF00646.33 KKK17340.1 - 1.4e-07 31.2 0.1 5.4e-07 29.3 0.1 2.0 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KKK17340.1 - 1.2e-06 28.3 0.2 1.2e-06 28.3 0.2 2.2 3 0 0 3 3 3 1 F-box-like Sugar_tr PF00083.24 KKK17341.1 - 8.5e-108 361.1 17.1 3.3e-107 359.2 17.1 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKK17341.1 - 6.8e-25 87.7 27.3 2.9e-18 65.9 8.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily WD40 PF00400.32 KKK17356.1 - 9.1e-47 156.1 15.6 5.1e-08 33.5 0.2 8.1 7 2 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKK17356.1 - 3.5e-11 43.3 0.7 0.00091 19.5 0.0 4.4 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KKK17356.1 - 2.7e-06 26.3 0.2 0.0001 21.1 0.2 2.5 3 0 0 3 3 3 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 KKK17356.1 - 0.0011 17.9 0.2 6.6 5.3 0.0 3.1 3 0 0 3 3 3 3 Nup133 N terminal like DUF1192 PF06698.11 KKK17356.1 - 0.063 13.3 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) ABC_tran_CTD PF16326.5 KKK17356.1 - 0.066 13.5 0.1 0.13 12.5 0.1 1.4 1 0 0 1 1 1 0 ABC transporter C-terminal domain Hira PF07569.11 KKK17356.1 - 0.13 12.0 0.9 6.4 6.4 0.1 2.6 3 0 0 3 3 3 0 TUP1-like enhancer of split SlyX PF04102.12 KKK17356.1 - 0.14 12.8 0.1 0.27 11.9 0.1 1.4 1 0 0 1 1 1 0 SlyX DUF4013 PF13197.6 KKK17356.1 - 0.25 11.2 0.0 0.45 10.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4013) Peptidase_M19 PF01244.21 KKK17357.1 - 1.7e-102 342.9 0.0 2.1e-102 342.6 0.0 1.1 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) Noelin-1 PF12308.8 KKK17366.1 - 0.041 13.9 1.7 0.1 12.6 1.7 1.7 1 0 0 1 1 1 0 Neurogenesis glycoprotein NOC3p PF07540.11 KKK17367.1 - 6.1e-31 106.7 0.2 2.5e-30 104.8 0.2 2.1 1 0 0 1 1 1 1 Nucleolar complex-associated protein CBF PF03914.17 KKK17367.1 - 1e-26 94.0 0.1 1e-26 94.0 0.1 2.4 4 0 0 4 4 4 1 CBF/Mak21 family DUF2570 PF10828.8 KKK17367.1 - 0.32 10.8 3.1 0.81 9.5 3.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) PRC2_HTH_1 PF18118.1 KKK17367.1 - 7.5 7.4 12.7 0.86 10.4 0.1 3.5 3 0 0 3 3 3 0 Polycomb repressive complex 2 tri-helical domain PLA2_B PF01735.18 KKK17368.1 - 8.7e-27 93.7 0.0 1.6e-26 92.8 0.0 1.4 1 1 0 1 1 1 1 Lysophospholipase catalytic domain DSPc PF00782.20 KKK17369.1 - 1.1e-09 38.2 0.0 2e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KKK17369.1 - 0.0051 16.4 0.0 0.0085 15.7 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PPR_2 PF13041.6 KKK17370.1 - 3.7e-13 49.4 0.1 0.00053 20.1 0.1 6.6 4 3 3 7 7 7 2 PPR repeat family PPR_long PF17177.4 KKK17370.1 - 1.7e-11 43.9 0.7 9.9e-08 31.6 0.1 2.6 1 1 1 2 2 2 2 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 KKK17370.1 - 7.4e-09 35.3 2.9 0.065 13.5 0.1 5.3 5 0 0 5 5 5 3 PPR repeat PPR_3 PF13812.6 KKK17370.1 - 8.6e-09 35.3 0.0 0.00022 21.2 0.0 4.4 3 1 1 4 4 4 2 Pentatricopeptide repeat domain Mic1 PF07035.12 KKK17370.1 - 0.00017 21.3 0.0 0.067 12.9 0.1 2.4 2 0 0 2 2 2 2 Colon cancer-associated protein Mic1-like PPR_1 PF12854.7 KKK17370.1 - 0.038 13.7 0.0 0.88 9.3 0.0 2.9 3 0 0 3 3 3 0 PPR repeat LSM PF01423.22 KKK17371.1 - 1.2e-11 44.1 0.0 1.3e-11 44.0 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KKK17371.1 - 0.076 13.2 0.0 0.086 13.0 0.0 1.1 1 0 0 1 1 1 0 Ataxin 2 SM domain Exo70 PF03081.15 KKK17372.1 - 5.3e-89 298.9 0.0 7.3e-89 298.4 0.0 1.2 1 0 0 1 1 1 1 Exo70 exocyst complex subunit Bap31_Bap29_C PF18035.1 KKK17372.1 - 0.12 12.4 0.0 0.37 10.8 0.0 1.8 1 0 0 1 1 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain DASH_Dam1 PF08653.10 KKK17372.1 - 0.13 12.1 0.3 57 3.6 0.0 3.6 3 0 0 3 3 3 0 DASH complex subunit Dam1 Prominin PF05478.11 KKK17372.1 - 0.15 10.0 0.6 0.24 9.3 0.6 1.2 1 0 0 1 1 1 0 Prominin Hyr1 PF15789.5 KKK17372.1 - 0.19 11.3 1.5 5.1 6.7 0.4 2.5 2 0 0 2 2 2 0 Hyphally regulated cell wall GPI-anchored protein 1 Lyase_1 PF00206.20 KKK17373.1 - 2.6e-21 76.3 0.0 4.9e-21 75.4 0.0 1.4 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.9 KKK17373.1 - 1.4e-18 67.1 0.0 5.1e-18 65.4 0.0 2.0 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus Hat1_N PF10394.9 KKK17376.1 - 1.3e-55 188.0 0.0 2.2e-55 187.3 0.0 1.4 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus Acetyltransf_1 PF00583.25 KKK17376.1 - 0.07 13.4 0.0 0.19 12.0 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family 3HCDH_N PF02737.18 KKK17377.1 - 1.5e-23 83.7 0.6 9e-22 77.8 0.0 2.2 1 1 1 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 KKK17377.1 - 2.3e-10 40.9 0.0 7.5e-10 39.3 0.0 1.8 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain Zip PF02535.22 KKK17378.1 - 4.1e-36 124.9 12.5 7.9e-28 97.6 5.2 3.1 2 1 0 2 2 2 2 ZIP Zinc transporter WD40 PF00400.32 KKK17379.1 - 1.7e-38 129.9 18.9 2.4e-05 25.0 0.0 7.6 8 0 0 8 8 8 6 WD domain, G-beta repeat F-box-like PF12937.7 KKK17379.1 - 2.5e-10 40.1 0.4 4.8e-10 39.2 0.4 1.5 1 0 0 1 1 1 1 F-box-like ANAPC4_WD40 PF12894.7 KKK17379.1 - 2.9e-08 33.9 0.6 0.23 11.8 0.0 5.0 1 1 4 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KKK17379.1 - 4.1e-06 25.7 6.4 0.02 13.5 0.2 5.0 1 1 5 6 6 6 2 Nucleoporin Nup120/160 WD40_like PF17005.5 KKK17379.1 - 3.4e-05 23.3 0.0 0.06 12.7 0.0 2.7 1 1 1 3 3 3 2 WD40-like domain F-box PF00646.33 KKK17379.1 - 0.00037 20.3 0.2 0.00078 19.3 0.2 1.6 1 0 0 1 1 1 1 F-box domain PALB2_WD40 PF16756.5 KKK17379.1 - 0.0046 15.9 3.4 9 5.1 0.1 4.0 3 1 1 4 4 4 2 Partner and localizer of BRCA2 WD40 domain PQQ_2 PF13360.6 KKK17379.1 - 0.008 15.8 4.4 0.012 15.2 1.7 2.4 1 1 2 3 3 3 1 PQQ-like domain DUF5046 PF16465.5 KKK17379.1 - 0.062 12.7 0.0 3.7 6.9 0.0 2.8 1 1 1 3 3 3 0 Domain of unknown function (DUF5046) F-box_5 PF18511.1 KKK17379.1 - 0.087 12.4 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 F-box PQQ_3 PF13570.6 KKK17379.1 - 0.16 12.5 8.1 16 6.1 0.1 4.8 4 1 0 4 4 3 0 PQQ-like domain BCDHK_Adom3 PF10436.9 KKK17380.1 - 1.5e-74 249.2 0.0 2.1e-74 248.8 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 KKK17380.1 - 2.4e-09 37.7 0.0 5e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PX PF00787.24 KKK17414.1 - 2.1e-19 69.6 0.0 3e-19 69.1 0.0 1.2 1 0 0 1 1 1 1 PX domain RPN7 PF10602.9 KKK17415.1 - 1.1e-53 181.6 0.1 2.2e-53 180.6 0.1 1.5 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 KKK17415.1 - 1.2e-10 41.9 0.8 3.6e-10 40.3 0.1 2.2 3 0 0 3 3 3 1 PCI domain LtrA PF06772.11 KKK17416.1 - 1.4e-12 47.5 17.5 1.4e-12 47.5 17.5 2.1 2 0 0 2 2 2 2 Bacterial low temperature requirement A protein (LtrA) LSM PF01423.22 KKK17417.1 - 1.1e-21 76.3 0.3 1.2e-21 76.2 0.3 1.0 1 0 0 1 1 1 1 LSM domain ATP_transf PF09830.9 KKK17418.1 - 6.2e-23 80.7 0.0 1e-22 80.0 0.0 1.4 1 0 0 1 1 1 1 ATP adenylyltransferase GalP_UDP_transf PF01087.22 KKK17418.1 - 0.019 15.4 0.0 0.041 14.3 0.0 1.5 1 0 0 1 1 1 0 Galactose-1-phosphate uridyl transferase, N-terminal domain RACo_linker PF17650.1 KKK17418.1 - 0.13 12.1 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 RACo linker region Peptidase_M1 PF01433.20 KKK17420.1 - 0.00012 21.7 0.0 0.00021 20.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 KKK17420.1 - 0.00052 20.3 0.0 0.055 13.7 0.0 2.4 2 0 0 2 2 2 2 Peptidase M1 N-terminal domain CDP-OH_P_transf PF01066.21 KKK17421.1 - 2.8e-16 60.0 0.1 2.8e-16 60.0 0.1 2.7 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Sdh_cyt PF01127.22 KKK17422.1 - 2.8e-25 88.7 3.2 4.5e-25 88.0 3.2 1.3 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit TAL_FSA PF00923.19 KKK17423.1 - 6.5e-50 170.1 0.0 7.8e-50 169.8 0.0 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase Adap_comp_sub PF00928.21 KKK17424.1 - 1.5e-91 306.4 0.0 2.1e-91 306.0 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KKK17424.1 - 8e-09 35.6 0.3 1.3e-08 34.8 0.3 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.9 KKK17424.1 - 0.16 11.4 0.0 0.63 9.4 0.0 1.8 2 0 0 2 2 2 0 Muniscin C-terminal mu homology domain Ribonucleas_3_3 PF14622.6 KKK17425.1 - 9.9e-30 103.3 0.0 1.7e-29 102.5 0.0 1.4 1 1 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 KKK17425.1 - 1.6e-08 35.1 0.0 5.2e-08 33.5 0.0 1.9 2 1 0 2 2 2 1 Ribonuclease III domain FGGY_C PF02782.16 KKK17426.1 - 3.3e-34 118.3 0.0 5.2e-34 117.7 0.0 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 KKK17426.1 - 2.5e-21 76.4 0.0 3.4e-13 49.8 0.0 2.3 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain Xpo1 PF08389.12 KKK17427.1 - 4.1e-44 150.2 0.1 3.4e-43 147.3 0.0 2.7 2 0 0 2 2 2 1 Exportin 1-like protein HEAT PF02985.22 KKK17427.1 - 0.00018 21.5 0.2 1.5 9.3 0.0 4.9 5 0 0 5 5 5 1 HEAT repeat TctA PF01970.16 KKK17427.1 - 0.038 12.7 0.0 0.068 11.9 0.0 1.3 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctA family Tom22 PF04281.13 KKK17427.1 - 0.076 12.8 1.2 2.7 7.8 0.1 2.4 2 0 0 2 2 2 0 Mitochondrial import receptor subunit Tom22 CelTOS PF18659.1 KKK17427.1 - 0.26 11.7 2.5 2.5 8.6 0.3 3.7 3 1 1 4 4 4 0 Cell-traversal protein for ookinetes and sporozoites Cation_efflux PF01545.21 KKK17428.1 - 4.5e-62 209.3 5.9 5.6e-62 209.0 5.9 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 KKK17428.1 - 1.1e-06 28.6 0.3 4.1e-06 26.8 0.0 2.1 2 0 0 2 2 2 1 Dimerisation domain of Zinc Transporter DUF808 PF05661.12 KKK17428.1 - 0.031 13.4 0.4 0.031 13.4 0.4 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF808) PAP2_3 PF14378.6 KKK17430.1 - 4.7e-41 140.6 13.1 4.7e-41 140.6 13.1 1.6 3 0 0 3 3 3 1 PAP2 superfamily PAP2 PF01569.21 KKK17430.1 - 0.0022 17.8 6.7 0.0022 17.8 6.7 2.2 1 1 2 3 3 3 1 PAP2 superfamily PAP2_C PF14360.6 KKK17430.1 - 0.013 16.0 2.1 0.013 16.0 2.1 2.6 3 0 0 3 3 3 0 PAP2 superfamily C-terminal Mito_carr PF00153.27 KKK17431.1 - 5.7e-41 138.4 0.1 1.2e-24 86.0 0.0 2.9 2 1 1 3 3 3 2 Mitochondrial carrier protein EF-hand_7 PF13499.6 KKK17431.1 - 8.4e-20 71.0 5.0 4.1e-09 36.7 0.9 3.4 3 1 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 KKK17431.1 - 1.4e-19 68.3 1.3 1.6e-06 27.6 0.1 5.5 5 0 0 5 5 5 4 EF-hand domain EF-hand_1 PF00036.32 KKK17431.1 - 1.1e-17 62.2 3.2 9.3e-07 28.0 0.1 5.4 6 0 0 6 6 6 3 EF hand EF-hand_8 PF13833.6 KKK17431.1 - 3.4e-11 42.8 5.1 0.0057 16.5 0.0 5.6 5 1 1 6 6 6 5 EF-hand domain pair EF-hand_5 PF13202.6 KKK17431.1 - 5e-10 38.4 0.9 3e-05 23.3 0.1 4.5 4 0 0 4 4 4 1 EF hand EF-hand_9 PF14658.6 KKK17431.1 - 0.0012 19.1 0.0 6.1 7.3 0.0 3.5 3 0 0 3 3 3 2 EF-hand domain Gaa1 PF04114.14 KKK17431.1 - 0.14 11.2 0.0 0.2 10.7 0.0 1.1 1 0 0 1 1 1 0 Gaa1-like, GPI transamidase component 6PGD PF00393.19 KKK17438.1 - 2.6e-83 279.7 0.0 3.8e-83 279.2 0.0 1.2 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain PNP_UDP_1 PF01048.20 KKK17438.1 - 4.7e-39 134.0 0.1 7e-39 133.5 0.1 1.3 1 0 0 1 1 1 1 Phosphorylase superfamily NAD_binding_2 PF03446.15 KKK17438.1 - 9.9e-28 97.3 0.1 2.2e-27 96.2 0.1 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 KKK17438.1 - 2.3e-05 24.4 0.7 9.3e-05 22.4 0.2 2.0 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 KKK17438.1 - 0.0022 17.6 0.2 0.0041 16.7 0.2 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.19 KKK17438.1 - 0.0022 17.4 0.1 0.0041 16.5 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox PF00070.27 KKK17438.1 - 0.0072 16.9 0.1 0.02 15.5 0.1 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase F420_oxidored PF03807.17 KKK17438.1 - 0.012 16.2 0.1 0.043 14.4 0.0 2.0 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.23 KKK17438.1 - 0.022 14.8 0.2 0.046 13.7 0.2 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.16 KKK17438.1 - 0.045 13.4 0.4 0.082 12.6 0.4 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox_2 PF07992.14 KKK17438.1 - 0.048 12.9 0.0 0.1 11.8 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_11 PF14833.6 KKK17438.1 - 0.14 12.4 0.0 2.6 8.3 0.0 2.3 2 0 0 2 2 2 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase DUF2235 PF09994.9 KKK17439.1 - 1.8e-94 316.3 0.0 2.5e-94 315.9 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) DUF1412 PF07203.11 KKK17440.1 - 0.15 12.3 0.2 0.32 11.2 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1412) Abhydrolase_6 PF12697.7 KKK17441.1 - 8.8e-06 26.5 0.1 1.3e-05 25.9 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.18 KKK17441.1 - 0.12 11.9 0.1 0.33 10.5 0.1 1.7 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) DUF3336 PF11815.8 KKK17442.1 - 5.1e-36 123.4 0.8 8.4e-36 122.7 0.8 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 KKK17442.1 - 1.9e-19 70.6 0.0 3.5e-19 69.8 0.0 1.4 1 0 0 1 1 1 1 Patatin-like phospholipase SKG6 PF08693.10 KKK17443.1 - 0.00032 20.1 1.3 0.00052 19.4 1.3 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain CD34_antigen PF06365.12 KKK17443.1 - 0.0012 18.5 0.0 0.0022 17.6 0.0 1.4 1 0 0 1 1 1 1 CD34/Podocalyxin family Syndecan PF01034.20 KKK17443.1 - 0.012 15.5 0.2 0.023 14.6 0.2 1.3 1 0 0 1 1 1 0 Syndecan domain Mid2 PF04478.12 KKK17443.1 - 0.02 14.7 0.0 0.035 13.9 0.0 1.4 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor EphA2_TM PF14575.6 KKK17443.1 - 0.032 15.1 0.0 0.16 12.8 0.0 2.1 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain CD99L2 PF12301.8 KKK17443.1 - 0.039 14.3 0.8 0.48 10.7 0.0 2.3 2 0 0 2 2 2 0 CD99 antigen like protein 2 Centro_C10orf90 PF17730.1 KKK17443.1 - 0.092 11.5 2.2 0.26 10.0 0.5 2.0 1 1 1 2 2 2 0 Centrosomal C10orf90 Amnionless PF14828.6 KKK17443.1 - 0.099 11.5 0.0 0.18 10.6 0.0 1.4 1 0 0 1 1 1 0 Amnionless Podoplanin PF05808.11 KKK17443.1 - 0.14 12.2 0.1 0.3 11.2 0.1 1.5 1 0 0 1 1 1 0 Podoplanin DUF2633 PF11119.8 KKK17443.1 - 0.18 11.7 4.1 0.38 10.7 4.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2633) Med30 PF11315.8 KKK17444.1 - 0.15 12.2 0.2 0.24 11.6 0.2 1.2 1 0 0 1 1 1 0 Mediator complex subunit 30 DAZAP2 PF11029.8 KKK17444.1 - 7.7 7.5 10.0 5.3 8.0 2.6 3.0 3 0 0 3 3 3 0 DAZ associated protein 2 (DAZAP2) AA_permease PF00324.21 KKK17446.1 - 1.5e-130 436.0 45.9 1.8e-130 435.7 45.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KKK17446.1 - 2.3e-30 105.8 50.8 2.8e-30 105.5 50.8 1.0 1 0 0 1 1 1 1 Amino acid permease Aldedh PF00171.22 KKK17447.1 - 1.6e-110 369.8 0.1 2e-110 369.5 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family HECT PF00632.25 KKK17448.1 - 6.5e-78 262.3 0.0 9.8e-78 261.7 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) HEAT PF02985.22 KKK17448.1 - 0.0032 17.6 3.9 0.21 11.9 0.0 4.4 5 0 0 5 5 5 1 HEAT repeat HEAT_EZ PF13513.6 KKK17448.1 - 0.026 15.1 0.2 0.35 11.4 0.0 3.0 3 0 0 3 3 3 0 HEAT-like repeat Arm PF00514.23 KKK17448.1 - 0.03 14.4 6.9 18 5.6 0.1 5.8 5 1 1 6 6 6 0 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.20 KKK17448.1 - 0.49 8.9 4.3 0.24 9.9 0.2 2.4 3 0 0 3 3 3 0 Adaptin N terminal region Pkinase PF00069.25 KKK17449.1 - 6.6e-08 32.2 0.1 7.1e-07 28.9 0.1 2.0 1 1 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 KKK17449.1 - 0.075 12.3 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 Kinase-like MutS_V PF00488.21 KKK17450.1 - 7.3e-68 228.3 0.1 1.3e-67 227.5 0.1 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KKK17450.1 - 5.8e-42 144.1 0.1 1.5e-41 142.8 0.1 1.8 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 KKK17450.1 - 7.5e-33 113.1 0.0 2.3e-32 111.6 0.0 1.9 2 0 0 2 2 2 1 MutS domain I MutS_II PF05188.17 KKK17450.1 - 2e-14 54.0 0.0 8.2e-14 52.0 0.0 2.1 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.18 KKK17450.1 - 3.1e-12 46.7 0.2 7e-12 45.5 0.2 1.6 1 0 0 1 1 1 1 MutS family domain IV AAA_29 PF13555.6 KKK17450.1 - 0.096 12.4 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 KKK17450.1 - 0.097 13.2 1.1 0.43 11.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_27 PF13514.6 KKK17450.1 - 0.14 11.7 0.0 0.33 10.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain tRNA-synt_1b PF00579.25 KKK17451.1 - 3.4e-68 230.1 0.1 3.9e-59 200.4 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (W and Y) TyrRSs_C PF16714.5 KKK17451.1 - 2e-50 169.6 0.0 4.8e-50 168.4 0.0 1.6 2 0 0 2 2 2 1 Tyrosyl-tRNA synthetase C-terminal domain PhaP_Bmeg PF09602.10 KKK17451.1 - 0.076 12.9 0.5 0.18 11.7 0.3 1.7 2 0 0 2 2 2 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) DUF2852 PF11014.8 KKK17451.1 - 0.33 11.1 2.1 2.2 8.5 0.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2852) tRNA-synt_2 PF00152.20 KKK17452.1 - 2.9e-92 309.1 0.0 9.8e-92 307.4 0.0 1.8 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KKK17452.1 - 0.00096 19.1 0.0 0.002 18.1 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2b PF00587.25 KKK17452.1 - 0.092 12.7 0.0 0.47 10.4 0.0 2.0 2 0 0 2 2 2 0 tRNA synthetase class II core domain (G, H, P, S and T) UbiA PF01040.18 KKK17453.1 - 5.2e-58 196.3 17.7 5.2e-58 196.3 17.7 1.6 1 1 1 2 2 2 1 UbiA prenyltransferase family DUF2486 PF10667.9 KKK17454.1 - 0.044 14.0 6.5 0.05 13.8 6.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2486) Joubert PF15392.6 KKK17454.1 - 0.2 11.3 1.8 0.24 11.1 1.8 1.1 1 0 0 1 1 1 0 Joubert syndrome-associated ORC6 PF05460.13 KKK17454.1 - 0.23 10.7 5.8 0.3 10.3 5.8 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) DUF4551 PF15087.6 KKK17454.1 - 1.5 7.5 2.9 1.8 7.3 2.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) CDK2AP PF09806.9 KKK17454.1 - 1.9 8.5 5.8 3.5 7.6 5.8 1.4 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein PQ-loop PF04193.14 KKK17455.1 - 1.1e-19 69.9 4.5 8.4e-10 38.3 1.2 2.7 2 0 0 2 2 2 2 PQ loop repeat Med8 PF10232.9 KKK17456.1 - 6.8e-32 110.9 15.7 1.5e-21 77.1 10.1 2.0 1 1 1 2 2 2 2 Mediator of RNA polymerase II transcription complex subunit 8 CENP-B_dimeris PF09026.10 KKK17456.1 - 0.00011 22.6 5.7 0.0002 21.7 5.7 1.5 1 0 0 1 1 1 1 Centromere protein B dimerisation domain Tub_N PF16322.5 KKK17456.1 - 0.0064 16.9 3.4 0.0096 16.4 3.4 1.3 1 0 0 1 1 1 1 Tubby N-terminal PPP4R2 PF09184.11 KKK17456.1 - 0.011 15.3 1.7 0.015 14.9 1.7 1.2 1 0 0 1 1 1 0 PPP4R2 RNA_pol_3_Rpc31 PF11705.8 KKK17456.1 - 0.012 15.9 9.5 0.018 15.3 9.5 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 TFIIA PF03153.13 KKK17456.1 - 0.1 12.6 3.7 0.13 12.2 3.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DNA_gyraseB PF00204.25 KKK17456.1 - 0.16 11.4 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 DNA gyrase B NOA36 PF06524.12 KKK17456.1 - 0.27 10.5 7.6 0.46 9.8 7.6 1.4 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 KKK17456.1 - 0.83 7.7 11.1 1.3 7.0 11.1 1.2 1 0 0 1 1 1 0 DNA polymerase phi Nucleo_P87 PF07267.11 KKK17456.1 - 1.1 8.0 3.1 1.5 7.5 3.1 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DUF4637 PF15470.6 KKK17456.1 - 1.5 8.6 8.8 0.38 10.5 5.5 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4637) Astro_capsid_p PF12226.8 KKK17456.1 - 4.3 6.4 8.6 6.9 5.7 8.6 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Lsr2 PF11774.8 KKK17456.1 - 4.5 7.5 6.9 1.9 8.6 3.4 2.2 2 0 0 2 2 2 0 Lsr2 Ubie_methyltran PF01209.18 KKK17457.1 - 3.7e-79 265.3 0.0 7.6e-79 264.3 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 KKK17457.1 - 1.2e-15 57.9 0.0 3.2e-15 56.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KKK17457.1 - 1.4e-14 54.5 0.0 9.8e-14 51.8 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain SIS PF01380.22 KKK17457.1 - 2e-13 50.3 0.1 1e-12 48.0 0.0 2.2 2 1 0 2 2 2 1 SIS domain Methyltransf_31 PF13847.6 KKK17457.1 - 5.1e-11 42.6 0.0 1.7e-10 40.9 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KKK17457.1 - 1.2e-08 35.6 0.0 3.1e-08 34.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain SIS_2 PF13580.6 KKK17457.1 - 1.3e-07 31.7 0.1 3.3e-05 23.9 0.1 2.3 1 1 1 2 2 2 2 SIS domain Methyltransf_23 PF13489.6 KKK17457.1 - 1.4e-06 28.3 0.0 1.4e-05 25.0 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain ADH_zinc_N PF00107.26 KKK17457.1 - 0.0042 17.1 0.0 1.6 8.7 0.0 2.5 2 0 0 2 2 2 2 Zinc-binding dehydrogenase CTP_transf_like PF01467.26 KKK17458.1 - 4e-27 95.2 0.0 5.8e-27 94.6 0.0 1.2 1 0 0 1 1 1 1 Cytidylyltransferase-like Peptidase_C13 PF01650.18 KKK17458.1 - 0.17 11.4 0.0 0.27 10.7 0.0 1.2 1 0 0 1 1 1 0 Peptidase C13 family Fungal_trans PF04082.18 KKK17459.1 - 2.6e-26 92.2 0.0 4.4e-26 91.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK17459.1 - 4.2e-06 26.8 9.4 8.5e-06 25.8 9.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BUD22 PF09073.10 KKK17460.1 - 1e-109 367.8 27.1 1.2e-109 367.6 27.1 1.0 1 0 0 1 1 1 1 BUD22 Pro_dh PF01619.18 KKK17461.1 - 2.5e-64 217.7 0.2 3e-64 217.4 0.2 1.1 1 0 0 1 1 1 1 Proline dehydrogenase OCD_Mu_crystall PF02423.15 KKK17462.1 - 4.2e-11 42.3 0.0 9e-11 41.3 0.0 1.5 1 1 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.20 KKK17462.1 - 0.00022 21.3 0.0 0.0095 16.0 0.0 2.6 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Glyco_tran_WecB PF03808.13 KKK17462.1 - 0.071 13.1 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family Proteasome_A_N PF10584.9 KKK17462.1 - 0.18 11.6 0.0 0.4 10.4 0.0 1.6 1 0 0 1 1 1 0 Proteasome subunit A N-terminal signature E1_dh PF00676.20 KKK17463.1 - 3.6e-87 292.1 0.0 4.4e-87 291.8 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 KKK17463.1 - 0.00015 21.6 0.0 0.0021 17.9 0.0 2.2 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain XFP_N PF09364.10 KKK17463.1 - 0.0073 15.2 0.0 0.015 14.1 0.0 1.5 1 0 0 1 1 1 1 XFP N-terminal domain SidC_N PF18219.1 KKK17463.1 - 0.17 10.9 0.1 0.24 10.3 0.1 1.1 1 0 0 1 1 1 0 SidC N-terminal domain Elongin_A PF06881.11 KKK17463.1 - 0.65 10.5 4.1 1.5 9.4 4.1 1.5 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A Ig_mannosidase PF17753.1 KKK17464.1 - 3.1e-20 71.7 0.1 8e-20 70.4 0.1 1.8 1 0 0 1 1 1 1 Ig-fold domain Mannosidase_ig PF17786.1 KKK17464.1 - 2e-12 47.5 0.0 5.1e-12 46.2 0.0 1.8 1 0 0 1 1 1 1 Mannosidase Ig/CBM-like domain DUF4299 PF14132.6 KKK17464.1 - 0.021 14.3 0.0 0.038 13.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4299) Complex1_30kDa PF00329.19 KKK17465.1 - 2.7e-45 153.9 0.0 3.7e-45 153.5 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit zf-RING_4 PF14570.6 KKK17466.1 - 2.5e-19 68.8 13.3 4.4e-19 68.0 13.3 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 KKK17466.1 - 3.4e-06 26.8 7.4 5.9e-06 26.0 7.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RRM_1 PF00076.22 KKK17466.1 - 5.2e-05 23.0 0.0 0.00012 21.8 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RING_2 PF13639.6 KKK17466.1 - 0.0011 19.2 11.5 0.0023 18.2 11.5 1.5 1 0 0 1 1 1 1 Ring finger domain Baculo_IE-1 PF05290.11 KKK17466.1 - 0.0012 18.8 5.1 0.0022 18.0 5.1 1.4 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) Prok-RING_4 PF14447.6 KKK17466.1 - 0.15 11.9 9.2 1.1 9.2 9.5 2.1 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 KKK17466.1 - 0.25 11.2 12.7 0.47 10.4 12.7 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DZR PF12773.7 KKK17466.1 - 2.3 8.3 9.8 31 4.7 9.8 2.3 1 1 0 1 1 1 0 Double zinc ribbon zf-RING_UBOX PF13445.6 KKK17466.1 - 5.2 7.2 10.8 11 6.1 10.8 1.6 1 0 0 1 1 1 0 RING-type zinc-finger NAD_binding_8 PF13450.6 KKK17467.1 - 4.6e-08 33.2 0.0 1e-07 32.0 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 KKK17467.1 - 4.1e-05 23.1 0.0 6.2e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.14 KKK17467.1 - 0.00075 18.8 0.0 0.014 14.6 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KKK17467.1 - 0.012 15.0 0.0 0.016 14.6 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KKK17467.1 - 0.022 14.0 0.0 0.035 13.4 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain DAO PF01266.24 KKK17467.1 - 0.022 14.3 0.0 0.044 13.4 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KKK17467.1 - 0.039 13.2 0.1 0.06 12.6 0.1 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KKK17467.1 - 0.048 12.9 0.0 0.085 12.1 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.12 KKK17467.1 - 0.12 11.4 0.1 0.22 10.5 0.1 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_binding_9 PF13454.6 KKK17467.1 - 0.15 12.0 0.2 1.4 8.9 0.0 2.4 3 0 0 3 3 3 0 FAD-NAD(P)-binding HI0933_like PF03486.14 KKK17467.1 - 0.17 10.6 0.0 0.24 10.1 0.0 1.1 1 0 0 1 1 1 0 HI0933-like protein Aldedh PF00171.22 KKK17468.1 - 4.5e-166 552.9 2.9 9.7e-156 518.9 0.7 2.0 1 1 1 2 2 2 2 Aldehyde dehydrogenase family HATPase_c PF02518.26 KKK17469.1 - 1.7e-32 112.2 0.0 7.3e-32 110.2 0.0 2.2 2 0 0 2 2 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KKK17469.1 - 2.1e-21 76.2 0.4 3.4e-20 72.3 0.0 2.8 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 KKK17469.1 - 2.3e-19 69.2 0.0 7.9e-19 67.5 0.0 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF_2 PF13185.6 KKK17469.1 - 1.4e-13 51.3 0.0 1.7e-12 47.8 0.0 2.6 2 0 0 2 2 2 1 GAF domain AAA_16 PF13191.6 KKK17469.1 - 1.5e-13 51.5 0.0 7.2e-13 49.3 0.0 2.2 1 0 0 1 1 1 1 AAA ATPase domain GAF PF01590.26 KKK17469.1 - 5.7e-08 33.5 0.0 1.5e-07 32.1 0.0 1.8 1 0 0 1 1 1 1 GAF domain Pkinase PF00069.25 KKK17469.1 - 2.6e-06 27.0 0.0 2.8e-05 23.6 0.0 2.5 3 0 0 3 3 3 1 Protein kinase domain GAF_3 PF13492.6 KKK17469.1 - 6.2e-06 26.6 0.0 2.1e-05 24.9 0.0 1.9 1 0 0 1 1 1 1 GAF domain NB-ARC PF00931.22 KKK17469.1 - 0.00028 20.1 0.4 0.5 9.5 0.0 3.4 4 0 0 4 4 4 2 NB-ARC domain HATPase_c_3 PF13589.6 KKK17469.1 - 0.0036 17.1 0.0 0.0081 16.0 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF3369 PF11849.8 KKK17469.1 - 0.0037 17.5 0.8 0.049 13.8 0.8 2.6 1 1 0 1 1 1 1 Domain of unknown function (DUF3369) TPR_1 PF00515.28 KKK17469.1 - 0.049 13.5 0.0 26 4.9 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat AAA_22 PF13401.6 KKK17469.1 - 0.059 13.6 0.0 24 5.2 0.0 3.1 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 KKK17469.1 - 0.069 13.0 0.0 0.22 11.4 0.0 1.8 1 0 0 1 1 1 0 RsgA GTPase TPR_8 PF13181.6 KKK17469.1 - 0.076 13.3 0.0 0.55 10.6 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat NACHT PF05729.12 KKK17469.1 - 0.097 12.6 0.0 1.2 9.0 0.0 2.5 2 0 0 2 2 2 0 NACHT domain TPR_MalT PF17874.1 KKK17469.1 - 0.12 11.8 7.2 1.6 8.0 0.7 3.2 4 0 0 4 4 4 0 MalT-like TPR region TPR_12 PF13424.6 KKK17469.1 - 0.53 10.6 11.0 2.1 8.7 0.1 5.1 5 1 0 5 5 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 KKK17469.1 - 1.6 9.7 10.9 1.2 10.1 0.0 5.2 5 1 1 6 6 4 0 Tetratricopeptide repeat TPR_9 PF13371.6 KKK17469.1 - 4 7.6 6.5 79 3.5 0.1 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat Sugar_tr PF00083.24 KKK17470.1 - 5.6e-61 206.8 29.4 6.8e-61 206.5 29.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKK17470.1 - 2.8e-19 69.3 34.7 4.1e-19 68.7 34.7 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Glyco_hydro_1 PF00232.18 KKK17471.1 - 1.2e-143 478.8 0.7 1.7e-143 478.3 0.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Glyco_hyd_65N_2 PF14498.6 KKK17471.1 - 2e-58 198.1 0.0 2.8e-58 197.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Allantoicase PF03561.15 KKK17472.1 - 2.9e-85 283.5 0.0 4e-42 143.6 0.0 2.1 2 0 0 2 2 2 2 Allantoicase repeat Cytochrome_CBB3 PF13442.6 KKK17473.1 - 0.11 12.9 0.0 0.14 12.5 0.0 1.3 1 0 0 1 1 1 0 Cytochrome C oxidase, cbb3-type, subunit III Fungal_trans_2 PF11951.8 KKK17474.1 - 3.1e-21 75.6 0.1 9.8e-14 50.9 0.1 2.6 2 2 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK17474.1 - 4e-06 26.8 6.7 7.6e-06 26.0 6.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.25 KKK17475.1 - 2.1e-65 220.7 0.0 3e-65 220.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK17475.1 - 1.9e-31 109.3 0.0 1.4e-30 106.4 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KKK17475.1 - 0.0016 17.5 0.1 0.0023 16.9 0.1 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KKK17475.1 - 0.0018 17.6 0.0 0.0032 16.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 KKK17475.1 - 0.0073 15.9 0.1 0.095 12.3 0.0 2.2 1 1 1 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 KKK17475.1 - 0.011 15.1 0.0 0.034 13.4 0.0 1.9 2 0 0 2 2 2 0 Kinase-like RIO1 PF01163.22 KKK17475.1 - 0.065 12.8 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 KKK17475.1 - 0.16 11.8 0.0 0.41 10.5 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family tRNA-synt_2b PF00587.25 KKK17476.1 - 2.3e-20 73.3 0.0 3.7e-20 72.6 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 KKK17476.1 - 7.4e-13 48.7 4.9 1.2e-12 48.0 4.9 1.3 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain FAM76 PF16046.5 KKK17476.1 - 0.00056 19.4 0.3 0.00088 18.7 0.3 1.3 1 0 0 1 1 1 1 FAM76 protein HOOK PF05622.12 KKK17476.1 - 0.023 12.9 3.1 0.032 12.4 3.1 1.1 1 0 0 1 1 1 0 HOOK protein GOLGA2L5 PF15070.6 KKK17476.1 - 0.024 13.3 5.3 0.033 12.8 5.3 1.1 1 0 0 1 1 1 0 Putative golgin subfamily A member 2-like protein 5 ING PF12998.7 KKK17476.1 - 0.042 14.4 5.0 0.077 13.6 5.0 1.3 1 0 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding CENP-F_leu_zip PF10473.9 KKK17476.1 - 0.067 13.2 6.6 0.13 12.3 5.8 1.8 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HAUS-augmin3 PF14932.6 KKK17476.1 - 0.07 12.7 5.0 0.13 11.8 5.0 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 FUSC PF04632.12 KKK17476.1 - 0.14 10.7 1.1 0.18 10.3 1.1 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Pil1 PF13805.6 KKK17476.1 - 0.14 11.6 4.8 0.23 10.9 4.8 1.2 1 0 0 1 1 1 0 Eisosome component PIL1 BLOC1_2 PF10046.9 KKK17476.1 - 0.17 12.2 2.1 0.2 11.9 0.1 1.9 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Spc7 PF08317.11 KKK17476.1 - 0.21 10.4 7.2 0.31 9.9 7.2 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein FapA PF03961.13 KKK17476.1 - 0.38 9.3 3.2 0.58 8.7 3.2 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF2968 PF11180.8 KKK17476.1 - 0.49 10.0 10.2 0.8 9.3 10.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) DUF3818 PF12825.7 KKK17476.1 - 0.5 9.3 2.0 0.74 8.8 2.0 1.1 1 0 0 1 1 1 0 Domain of unknown function in PX-proteins (DUF3818) ABC_tran_CTD PF16326.5 KKK17476.1 - 1.3 9.3 11.1 2 8.7 6.9 2.5 1 1 1 2 2 2 0 ABC transporter C-terminal domain TMF_DNA_bd PF12329.8 KKK17476.1 - 1.5 8.9 9.7 3.8 7.6 7.9 2.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF4140 PF13600.6 KKK17476.1 - 4 7.9 10.8 9.2 6.8 0.4 2.5 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) DivIC PF04977.15 KKK17476.1 - 5.2 6.9 10.1 10 6.0 3.5 2.5 1 1 1 2 2 2 0 Septum formation initiator BTB PF00651.31 KKK17477.1 - 0.14 12.3 0.0 0.63 10.3 0.0 2.0 2 0 0 2 2 2 0 BTB/POZ domain DUF4267 PF14087.6 KKK17481.1 - 1.3e-27 96.0 2.8 2.7e-27 95.0 2.8 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) adh_short PF00106.25 KKK17481.1 - 1.6e-14 53.8 0.0 4.6e-14 52.3 0.0 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KKK17481.1 - 8e-12 45.2 0.0 1.4e-11 44.5 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase UT PF03253.14 KKK17481.1 - 0.026 13.7 2.8 0.039 13.1 2.8 1.3 1 0 0 1 1 1 0 Urea transporter Epimerase PF01370.21 KKK17481.1 - 0.12 11.8 0.0 0.24 10.8 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Peroxidase_2 PF01328.17 KKK17482.1 - 7.2e-51 173.4 0.0 9e-51 173.1 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 p450 PF00067.22 KKK17483.1 - 3.2e-56 191.0 0.0 4.4e-56 190.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KKK17484.1 - 2.7e-53 181.4 0.0 3.9e-53 180.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 ketoacyl-synt PF00109.26 KKK17485.1 - 1.9e-80 270.1 0.0 4.3e-80 268.9 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain SAT PF16073.5 KKK17485.1 - 6.6e-71 238.8 0.8 1.3e-70 237.8 0.1 1.9 2 0 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Thioesterase PF00975.20 KKK17485.1 - 2.2e-43 149.0 0.0 1.5e-41 143.0 0.0 2.5 2 0 0 2 2 2 1 Thioesterase domain Acyl_transf_1 PF00698.21 KKK17485.1 - 3.6e-38 131.9 0.0 1.6e-36 126.5 0.0 2.4 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KKK17485.1 - 1.7e-34 118.4 0.1 3.7e-34 117.3 0.1 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.25 KKK17485.1 - 1.8e-18 66.6 11.2 3.7e-10 40.0 0.8 2.8 3 0 0 3 3 3 2 Phosphopantetheine attachment site PS-DH PF14765.6 KKK17485.1 - 7.1e-16 58.3 0.0 1.2e-15 57.6 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase KAsynt_C_assoc PF16197.5 KKK17485.1 - 2.7e-08 34.2 0.0 6.2e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Thiolase_N PF00108.23 KKK17485.1 - 0.002 17.6 0.4 0.0045 16.4 0.0 1.8 2 0 0 2 2 2 1 Thiolase, N-terminal domain Abhydrolase_6 PF12697.7 KKK17485.1 - 0.0059 17.2 5.5 0.52 10.9 0.0 3.9 4 0 0 4 4 4 2 Alpha/beta hydrolase family MFS_1 PF07690.16 KKK17486.1 - 7.3e-13 48.2 14.3 9.3e-13 47.8 14.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily CVNH PF08881.10 KKK17488.1 - 5.6e-27 94.4 0.6 7.7e-27 93.9 0.6 1.2 1 0 0 1 1 1 1 CVNH domain Rick_17kDa_Anti PF05433.15 KKK17488.1 - 7.8e-07 28.9 13.6 1.2e-06 28.3 13.6 1.3 1 0 0 1 1 1 1 Glycine zipper 2TM domain DUF2076 PF09849.9 KKK17488.1 - 0.00051 20.2 4.1 0.0007 19.7 4.1 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) Gly-zipper_Omp PF13488.6 KKK17488.1 - 0.001 19.0 9.0 0.0016 18.4 9.0 1.3 1 0 0 1 1 1 1 Glycine zipper TraT PF05818.12 KKK17488.1 - 0.0073 16.0 0.2 0.011 15.4 0.2 1.2 1 0 0 1 1 1 1 Enterobacterial TraT complement resistance protein DUF533 PF04391.12 KKK17488.1 - 0.024 14.2 0.0 0.039 13.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF533) Transgly_assoc PF04226.13 KKK17488.1 - 3 8.2 10.9 4.6 7.6 10.9 1.3 1 0 0 1 1 1 0 Transglycosylase associated protein FMO-like PF00743.19 KKK17489.1 - 9.6e-16 57.3 0.0 4.5e-14 51.8 0.0 2.4 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 KKK17489.1 - 8.6e-09 35.5 0.0 7.2e-08 32.6 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KKK17489.1 - 7.8e-07 28.6 0.0 0.00019 20.8 0.0 2.3 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KKK17489.1 - 5.2e-06 25.8 0.0 0.00032 20.0 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 KKK17489.1 - 5.9e-05 22.8 0.0 1.7 8.1 0.0 3.2 2 1 1 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KKK17489.1 - 7.7e-05 22.1 0.0 0.032 13.5 0.0 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KKK17489.1 - 0.056 13.4 0.3 1.4 8.9 0.0 3.1 4 0 0 4 4 4 0 FAD-NAD(P)-binding LBR_tudor PF09465.10 KKK17489.1 - 0.085 12.7 0.1 0.21 11.4 0.1 1.6 1 0 0 1 1 1 0 Lamin-B receptor of TUDOR domain Thi4 PF01946.17 KKK17489.1 - 0.11 11.7 0.0 0.26 10.5 0.0 1.5 1 0 0 1 1 1 0 Thi4 family Aldo_ket_red PF00248.21 KKK17490.1 - 1.8e-65 221.0 0.0 2.2e-65 220.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family adh_short_C2 PF13561.6 KKK17491.1 - 1.3e-59 201.7 1.8 1.8e-59 201.2 1.8 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KKK17491.1 - 1.9e-52 177.6 0.8 2.5e-52 177.2 0.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KKK17491.1 - 1.9e-16 60.5 0.3 2.7e-16 60.0 0.3 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KKK17491.1 - 0.00073 19.1 0.3 0.0011 18.4 0.3 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 KKK17491.1 - 0.013 14.9 0.2 0.082 12.2 0.1 2.0 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF374 PF04028.13 KKK17491.1 - 0.042 13.4 0.1 0.2 11.2 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF374) Shikimate_DH PF01488.20 KKK17491.1 - 0.12 12.4 0.1 0.19 11.8 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 KKK17491.1 - 0.13 11.6 0.2 0.25 10.7 0.2 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain MARCKS PF02063.17 KKK17491.1 - 0.22 11.5 1.5 0.3 11.0 1.5 1.1 1 0 0 1 1 1 0 MARCKS family EthD PF07110.11 KKK17492.1 - 3e-16 60.3 0.3 5e-16 59.6 0.3 1.4 1 0 0 1 1 1 1 EthD domain GST_C PF00043.25 KKK17492.1 - 5.5e-12 45.8 0.0 1.3e-11 44.5 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KKK17492.1 - 6.6e-12 45.6 0.0 1.4e-11 44.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KKK17492.1 - 2.3e-07 31.1 0.0 1.2e-06 28.8 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KKK17492.1 - 2e-06 27.9 0.0 5.9e-06 26.4 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KKK17492.1 - 1e-05 25.7 0.1 0.00011 22.5 0.0 2.6 3 1 0 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KKK17492.1 - 0.00016 21.6 0.1 0.00042 20.3 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain MmlI PF09448.10 KKK17492.1 - 0.0016 18.9 0.0 0.0034 17.8 0.0 1.5 1 0 0 1 1 1 1 Methylmuconolactone methyl-isomerase Big_3 PF07523.12 KKK17492.1 - 0.14 12.5 0.0 0.26 11.6 0.0 1.4 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 3) Scaffolding_pro PF11418.8 KKK17507.1 - 0.37 11.4 7.5 0.069 13.7 0.3 3.6 3 0 0 3 3 3 0 Phi29 scaffolding protein Pkinase PF00069.25 KKK17508.1 - 8.9e-69 231.8 0.0 1.2e-68 231.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK17508.1 - 8.3e-31 107.2 0.0 1.2e-30 106.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 KKK17508.1 - 3e-15 56.6 1.7 2.4e-14 53.8 1.7 2.7 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.6 KKK17508.1 - 1.3e-08 34.5 0.0 4.4e-08 32.8 0.0 1.7 1 1 1 2 2 2 1 Kinase-like C2 PF00168.30 KKK17508.1 - 1.9e-08 34.5 0.0 3e-06 27.5 0.1 2.5 2 0 0 2 2 2 1 C2 domain Haspin_kinase PF12330.8 KKK17508.1 - 0.00023 20.2 0.2 0.00044 19.3 0.2 1.4 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KKK17508.1 - 0.0071 16.3 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.6 KKK17508.1 - 0.042 13.5 0.4 3.5 7.2 0.1 2.4 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Choline_kinase PF01633.20 KKK17508.1 - 0.051 13.1 0.1 0.12 12.0 0.1 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.14 KKK17508.1 - 0.1 11.9 0.1 0.16 11.3 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TMA7 PF09072.10 KKK17508.1 - 1.8 9.4 5.0 13 6.7 1.9 2.7 2 0 0 2 2 2 0 Translation machinery associated TMA7 F-box-like PF12937.7 KKK17509.1 - 0.0041 17.0 0.1 0.01 15.7 0.1 1.7 1 0 0 1 1 1 1 F-box-like AAA PF00004.29 KKK17510.1 - 1.3e-40 138.8 0.0 2.6e-40 137.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 KKK17510.1 - 4.1e-19 68.3 0.2 9.1e-19 67.2 0.2 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 KKK17510.1 - 4.6e-10 39.1 0.0 1e-09 38.0 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 KKK17510.1 - 6.5e-05 22.7 0.0 0.00016 21.5 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KKK17510.1 - 9.8e-05 22.4 1.1 0.00028 20.9 0.1 2.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KKK17510.1 - 0.0002 21.8 1.5 0.024 15.0 0.0 2.9 2 1 1 3 3 3 1 AAA ATPase domain AAA_2 PF07724.14 KKK17510.1 - 0.00083 19.5 1.7 0.012 15.8 0.0 3.4 3 1 0 3 3 3 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 KKK17510.1 - 0.0016 18.7 0.7 0.2 11.9 0.0 3.0 2 1 1 3 3 3 1 AAA domain DUF815 PF05673.13 KKK17510.1 - 0.004 16.3 0.0 0.011 15.0 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF815) PhoH PF02562.16 KKK17510.1 - 0.0058 16.1 0.2 0.08 12.4 0.1 2.2 2 0 0 2 2 2 1 PhoH-like protein Mg_chelatase PF01078.21 KKK17510.1 - 0.013 14.9 0.1 0.037 13.4 0.0 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 KKK17510.1 - 0.013 15.6 0.0 0.043 14.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 KKK17510.1 - 0.065 13.0 0.1 0.16 11.7 0.1 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_7 PF12775.7 KKK17510.1 - 0.13 11.8 0.0 0.34 10.4 0.0 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region Atg14 PF10186.9 KKK17510.1 - 0.24 10.4 4.7 2.3 7.2 5.0 2.0 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 AAA_11 PF13086.6 KKK17510.1 - 0.47 10.2 0.0 0.47 10.2 0.0 2.8 2 1 1 3 3 3 0 AAA domain DUF496 PF04363.12 KKK17510.1 - 0.99 9.5 9.2 0.28 11.2 0.4 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF496) CLZ PF16526.5 KKK17510.1 - 4.1 7.8 11.1 0.89 10.0 6.5 2.4 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels PGM_PMM_I PF02878.16 KKK17511.1 - 1.3e-14 54.1 0.1 5.6e-06 26.1 0.0 2.8 1 1 1 2 2 2 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.20 KKK17511.1 - 5.8e-11 42.4 0.4 2e-10 40.7 0.4 2.0 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_II PF02879.16 KKK17511.1 - 0.00064 20.3 0.1 0.003 18.1 0.1 2.2 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 KKK17511.1 - 0.057 13.6 0.1 0.28 11.4 0.1 2.1 1 1 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III DEAD PF00270.29 KKK17512.1 - 3.4e-45 154.0 0.0 5.3e-45 153.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KKK17512.1 - 6.2e-30 103.8 0.0 3.7e-29 101.3 0.0 2.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KKK17512.1 - 3.3e-05 23.9 0.0 9.9e-05 22.4 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF1087 PF06465.13 KKK17512.1 - 0.19 11.8 1.3 0.49 10.5 1.3 1.8 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1087) Methyltransf_25 PF13649.6 KKK17513.1 - 8.1e-14 52.1 0.0 2e-13 50.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KKK17513.1 - 1.6e-12 47.4 0.0 3.3e-12 46.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KKK17513.1 - 5e-11 42.5 0.0 7.8e-11 41.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 KKK17513.1 - 6.1e-10 39.6 0.0 2e-09 38.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KKK17513.1 - 2e-07 31.0 0.0 6.1e-07 29.4 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KKK17513.1 - 3.5e-06 27.7 0.0 7.7e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 KKK17513.1 - 1.7e-05 23.9 0.0 2.5e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) MTS PF05175.14 KKK17513.1 - 2.4e-05 24.0 0.1 5.2e-05 22.9 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase small domain CMAS PF02353.20 KKK17513.1 - 2.8e-05 23.5 0.0 4.1e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.7 KKK17513.1 - 6.9e-05 22.8 0.2 0.00021 21.3 0.1 1.8 1 1 1 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 KKK17513.1 - 0.0004 19.8 0.0 0.00064 19.1 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.6 KKK17513.1 - 0.001 19.1 0.0 0.0021 18.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 KKK17513.1 - 0.0028 17.8 0.0 0.0071 16.5 0.0 1.7 2 0 0 2 2 2 1 FtsJ-like methyltransferase PRMT5 PF05185.16 KKK17513.1 - 0.0072 16.2 0.0 0.014 15.3 0.0 1.4 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_16 PF10294.9 KKK17513.1 - 0.0087 15.8 0.0 0.013 15.2 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase PCMT PF01135.19 KKK17513.1 - 0.023 14.5 0.1 0.038 13.7 0.1 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_4 PF02390.17 KKK17513.1 - 0.032 13.7 0.3 0.068 12.6 0.1 1.6 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_24 PF13578.6 KKK17513.1 - 0.085 13.9 0.0 0.23 12.5 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain DOT1 PF08123.13 KKK17513.1 - 0.1 12.1 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 Rsm22 PF09243.10 KKK17513.1 - 0.12 11.6 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial small ribosomal subunit Rsm22 RPN6_N PF18055.1 KKK17514.1 - 8.1e-32 110.0 9.6 2.9e-31 108.2 2.8 3.2 3 1 0 3 3 3 1 26S proteasome regulatory subunit RPN6 N-terminal domain PCI PF01399.27 KKK17514.1 - 1.4e-21 77.0 0.0 7.3e-21 74.7 0.1 2.2 2 1 0 2 2 2 1 PCI domain RPN6_C_helix PF18503.1 KKK17514.1 - 3.7e-10 39.4 0.1 1.1e-09 37.9 0.1 1.9 1 0 0 1 1 1 1 26S proteasome subunit RPN6 C-terminal helix domain DDRGK PF09756.9 KKK17514.1 - 3.3e-05 23.6 0.1 3.3e-05 23.6 0.1 1.6 2 0 0 2 2 2 1 DDRGK domain TPR_MalT PF17874.1 KKK17514.1 - 0.00065 19.2 5.5 0.00084 18.8 2.0 2.4 2 0 0 2 2 2 1 MalT-like TPR region TPR_12 PF13424.6 KKK17514.1 - 0.0045 17.2 21.5 0.031 14.6 4.4 4.7 5 0 0 5 5 5 2 Tetratricopeptide repeat HTH_Crp_2 PF13545.6 KKK17514.1 - 0.0045 16.9 0.1 0.44 10.6 0.0 2.8 3 0 0 3 3 3 1 Crp-like helix-turn-helix domain DprA_WH PF17782.1 KKK17514.1 - 0.06 13.5 0.1 0.4 10.8 0.0 2.4 3 0 0 3 3 3 0 DprA winged helix domain DUF3496 PF12001.8 KKK17514.1 - 0.092 13.1 0.7 0.86 10.0 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3496) Prefoldin_2 PF01920.20 KKK17514.1 - 0.16 11.9 3.0 0.21 11.6 0.7 2.4 2 0 0 2 2 2 0 Prefoldin subunit TPR_14 PF13428.6 KKK17514.1 - 0.76 10.8 12.6 13 6.9 0.1 5.1 5 0 0 5 5 4 0 Tetratricopeptide repeat SWIB PF02201.18 KKK17515.1 - 9.8e-24 83.0 0.0 1.6e-23 82.3 0.0 1.4 1 0 0 1 1 1 1 SWIB/MDM2 domain MAGE PF01454.19 KKK17516.1 - 1.4e-20 73.9 0.3 1.4e-20 73.9 0.3 1.5 2 0 0 2 2 2 1 MAGE family Ribosomal_L27e PF01777.18 KKK17517.1 - 9e-39 131.7 2.9 1.4e-38 131.1 2.9 1.3 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.29 KKK17517.1 - 0.00022 21.0 0.7 0.00063 19.6 0.2 2.1 2 0 0 2 2 2 1 KOW motif Perilipin PF03036.16 KKK17518.1 - 0.025 13.6 0.0 0.032 13.3 0.0 1.1 1 0 0 1 1 1 0 Perilipin family SGP PF17228.2 KKK17518.1 - 1.2 10.0 7.0 0.13 13.2 2.4 1.7 2 0 0 2 2 2 0 Sulphur globule protein TRAM_LAG1_CLN8 PF03798.16 KKK17519.1 - 4.4e-54 183.3 19.3 4.4e-54 183.3 19.3 1.6 2 0 0 2 2 2 1 TLC domain SUIM_assoc PF16619.5 KKK17519.1 - 0.15 12.2 0.1 0.27 11.3 0.1 1.4 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Curto_V3 PF07436.11 KKK17519.1 - 6.7 7.2 6.2 1.3 9.5 0.2 2.7 3 0 0 3 3 3 0 Curtovirus V3 protein Brix PF04427.18 KKK17520.1 - 2.1e-50 171.6 0.3 3.8e-50 170.7 0.3 1.4 1 0 0 1 1 1 1 Brix domain RAP1 PF07218.11 KKK17520.1 - 0.52 8.5 10.1 0.65 8.2 10.1 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) PBP_sp32 PF07222.12 KKK17520.1 - 4.9 6.5 8.9 8 5.8 8.9 1.4 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Per1 PF04080.13 KKK17521.1 - 6.8e-101 337.3 16.8 8.2e-101 337.1 16.8 1.1 1 0 0 1 1 1 1 Per1-like family YWFCY PF14293.6 KKK17521.1 - 3.3 8.1 5.6 8.7 6.7 3.1 2.6 2 1 0 2 2 2 0 YWFCY protein Sof1 PF04158.14 KKK17522.1 - 6.3e-31 106.5 15.9 1e-30 105.8 15.9 1.4 1 0 0 1 1 1 1 Sof1-like domain WD40 PF00400.32 KKK17522.1 - 5.4e-22 77.7 0.6 7.1e-06 26.7 0.0 5.0 5 0 0 5 5 5 3 WD domain, G-beta repeat Ge1_WD40 PF16529.5 KKK17522.1 - 2.4e-05 23.5 0.0 0.0045 16.0 0.0 2.4 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein ANAPC4_WD40 PF12894.7 KKK17522.1 - 0.00031 21.0 0.0 0.46 10.8 0.0 3.3 1 1 3 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain adh_short PF00106.25 KKK17523.1 - 4.5e-37 127.4 0.3 6.7e-37 126.9 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KKK17523.1 - 2e-27 96.3 0.0 2.8e-27 95.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KKK17523.1 - 2.8e-08 33.9 0.3 5.9e-08 32.8 0.3 1.4 1 1 0 1 1 1 1 KR domain DUF1776 PF08643.10 KKK17523.1 - 0.00032 20.2 0.1 0.00066 19.1 0.1 1.4 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) CTNNB1_binding PF08347.11 KKK17523.1 - 0.044 14.0 0.0 0.063 13.5 0.0 1.3 1 0 0 1 1 1 0 N-terminal CTNNB1 binding CoA_transf_3 PF02515.17 KKK17524.1 - 7.2e-128 426.8 0.0 9.8e-128 426.4 0.0 1.2 1 0 0 1 1 1 1 CoA-transferase family III PHD PF00628.29 KKK17524.1 - 7.6e-10 38.5 9.9 1.6e-09 37.5 9.9 1.6 1 0 0 1 1 1 1 PHD-finger C1_1 PF00130.22 KKK17524.1 - 0.0032 17.3 4.1 0.0068 16.3 4.1 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) FYVE_2 PF02318.16 KKK17524.1 - 0.0042 17.3 2.9 0.0074 16.5 2.9 1.3 1 0 0 1 1 1 1 FYVE-type zinc finger Herpes_UL52 PF03121.15 KKK17524.1 - 0.0062 16.5 2.7 0.011 15.6 2.7 1.4 1 0 0 1 1 1 1 Herpesviridae UL52/UL70 DNA primase zf-RRPl_C4 PF17026.5 KKK17524.1 - 0.25 11.4 2.2 0.54 10.4 2.2 1.5 1 0 0 1 1 1 0 Putative ribonucleoprotein zinc-finger pf C4 type Prok-RING_1 PF14446.6 KKK17524.1 - 0.39 10.7 5.7 0.8 9.7 5.7 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 PHD_2 PF13831.6 KKK17524.1 - 0.85 9.2 9.9 0.15 11.7 5.3 2.2 2 1 0 2 2 2 0 PHD-finger Lum_binding PF00677.17 KKK17525.1 - 1.1e-43 147.1 2.1 5.9e-22 77.5 0.7 2.3 2 0 0 2 2 2 2 Lumazine binding domain TauD PF02668.16 KKK17526.1 - 1.5e-40 139.7 1.6 1.9e-40 139.4 1.6 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 KKK17526.1 - 2.6e-05 24.8 0.0 5e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF971) CsiD PF08943.10 KKK17526.1 - 0.11 11.6 0.1 0.33 10.0 0.0 1.7 2 0 0 2 2 2 0 CsiD Mito_carr PF00153.27 KKK17527.1 - 6.3e-63 208.7 1.7 7.4e-22 77.1 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein MS_channel PF00924.18 KKK17528.1 - 5.4e-23 81.6 2.0 5.4e-23 81.6 2.0 1.8 2 0 0 2 2 2 1 Mechanosensitive ion channel EF-hand_5 PF13202.6 KKK17528.1 - 0.00024 20.5 0.1 0.00057 19.3 0.1 1.7 1 0 0 1 1 1 1 EF hand EF-hand_1 PF00036.32 KKK17528.1 - 0.00066 19.0 0.4 0.0016 17.8 0.4 1.7 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 KKK17528.1 - 0.0014 18.4 0.0 0.0038 17.0 0.0 1.8 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 KKK17528.1 - 0.014 15.9 0.3 0.038 14.4 0.3 1.7 1 0 0 1 1 1 0 EF-hand domain pair TauD PF02668.16 KKK17529.1 - 1.1e-44 153.3 0.1 1.6e-44 152.7 0.1 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 KKK17529.1 - 2e-05 25.1 0.0 5.2e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF971) CsiD PF08943.10 KKK17529.1 - 0.00035 19.8 0.1 0.00076 18.7 0.1 1.6 1 1 0 1 1 1 1 CsiD 2OG-FeII_Oxy_3 PF13640.6 KKK17529.1 - 0.043 14.7 0.2 0.45 11.4 0.2 2.3 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Ponericin PF07442.11 KKK17529.1 - 8.9 6.4 5.7 4 7.6 1.3 2.2 2 0 0 2 2 2 0 Ponericin Tubulin PF00091.25 KKK17530.1 - 1.7e-66 224.2 0.0 2.3e-66 223.8 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KKK17530.1 - 5.2e-46 155.9 0.0 8.3e-46 155.3 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 KKK17530.1 - 0.00041 20.1 0.0 0.0008 19.1 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain adh_short_C2 PF13561.6 KKK17555.1 - 2e-48 165.0 0.0 2.4e-48 164.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KKK17555.1 - 2.8e-44 150.9 0.0 3.7e-44 150.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KKK17555.1 - 3.9e-07 30.1 0.0 6.6e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 KR domain Trehalase PF01204.18 KKK17556.1 - 2.3e-197 656.9 0.1 2.7e-197 656.6 0.1 1.0 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.11 KKK17556.1 - 1.7e-17 62.8 0.0 2.9e-17 62.1 0.0 1.4 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain ICL PF00463.21 KKK17557.1 - 0 1011.0 3.9 0 1010.8 3.9 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 KKK17557.1 - 1.1e-11 44.7 0.3 3.3e-11 43.1 0.1 1.9 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase DUF3197 PF11432.8 KKK17557.1 - 0.03 14.2 0.5 6.9 6.6 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3197) Aldedh PF00171.22 KKK17558.1 - 1.4e-70 238.1 0.0 1.7e-70 237.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Gram_pos_anchor PF00746.21 KKK17559.1 - 0.35 10.9 1.3 0.67 10.0 1.3 1.4 1 0 0 1 1 1 0 LPXTG cell wall anchor motif OTU PF02338.19 KKK17560.1 - 4e-21 75.8 0.1 5.6e-20 72.1 0.1 2.3 1 1 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 KKK17560.1 - 1.6e-07 31.0 0.0 9.2e-06 25.3 0.0 2.4 2 0 0 2 2 2 1 Peptidase C65 Otubain FUSC PF04632.12 KKK17560.1 - 1.5 7.3 3.8 2 6.9 3.8 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF4407 PF14362.6 KKK17560.1 - 9.2 5.5 11.4 14 4.9 11.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Malate_synthase PF01274.22 KKK17561.1 - 1.5e-36 125.7 0.0 1.7e-36 125.6 0.0 1.0 1 0 0 1 1 1 1 Malate synthase Gln-synt_C PF00120.24 KKK17562.1 - 2.8e-82 276.5 0.0 3.3e-82 276.3 0.0 1.0 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Viral_alk_exo PF01771.17 KKK17562.1 - 0.28 10.0 0.0 0.49 9.2 0.0 1.3 1 0 0 1 1 1 0 Viral alkaline exonuclease Amino_oxidase PF01593.24 KKK17564.1 - 4.6e-69 233.9 0.7 8e-69 233.1 0.7 1.4 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KKK17564.1 - 3.5e-08 33.6 0.1 8.2e-08 32.4 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KKK17564.1 - 0.0023 17.6 4.1 0.056 13.0 0.4 3.2 2 2 1 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KKK17564.1 - 0.0057 15.9 0.2 0.036 13.3 0.2 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KKK17564.1 - 0.0066 15.7 0.0 0.013 14.8 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 KKK17564.1 - 0.0074 15.6 0.0 0.081 12.1 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KKK17564.1 - 0.026 14.5 0.7 1.9 8.5 0.1 3.0 3 0 0 3 3 3 0 FAD-NAD(P)-binding Pyr_redox PF00070.27 KKK17564.1 - 0.037 14.6 0.1 0.79 10.3 0.1 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KKK17564.1 - 0.055 12.7 2.0 0.14 11.4 0.2 2.5 4 0 0 4 4 4 0 FAD binding domain GIDA PF01134.22 KKK17564.1 - 0.16 11.0 0.0 0.34 9.9 0.0 1.5 2 0 0 2 2 2 0 Glucose inhibited division protein A MBOAT_2 PF13813.6 KKK17565.1 - 4.9e-20 71.6 4.6 4.9e-20 71.6 4.6 2.0 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family FERM_F1 PF18379.1 KKK17565.1 - 0.053 13.5 0.4 0.25 11.4 0.4 2.0 2 0 0 2 2 2 0 FERM F1 ubiquitin-like domain CVNH PF08881.10 KKK17566.1 - 4.3e-08 33.8 0.0 4.8e-08 33.6 0.0 1.0 1 0 0 1 1 1 1 CVNH domain TB2_DP1_HVA22 PF03134.19 KKK17568.1 - 1.1e-23 83.0 8.5 1.8e-23 82.3 8.5 1.4 1 0 0 1 1 1 1 TB2/DP1, HVA22 family CHCH PF06747.13 KKK17569.1 - 5.3e-07 29.6 7.6 7.4e-07 29.2 7.6 1.2 1 0 0 1 1 1 1 CHCH domain CX9C PF16860.5 KKK17569.1 - 0.0094 15.9 1.0 0.3 11.1 0.2 2.2 2 0 0 2 2 2 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Toxin_25 PF08095.11 KKK17569.1 - 0.02 14.8 0.6 0.02 14.8 0.6 2.1 2 1 0 2 2 2 0 Hefutoxin family Cmc1 PF08583.10 KKK17569.1 - 0.02 14.9 5.3 0.049 13.7 5.3 1.6 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like COX17 PF05051.13 KKK17569.1 - 0.13 12.7 2.6 0.19 12.1 2.6 1.2 1 0 0 1 1 1 0 Cytochrome C oxidase copper chaperone (COX17) BPL_N PF09825.9 KKK17570.1 - 5.2e-148 493.1 0.0 6.7e-148 492.8 0.0 1.1 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.19 KKK17570.1 - 8.8e-26 90.4 0.1 1.4e-25 89.7 0.1 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_C PF02237.17 KKK17570.1 - 0.00012 21.9 0.1 0.00042 20.2 0.0 1.9 2 0 0 2 2 2 1 Biotin protein ligase C terminal domain p450 PF00067.22 KKK17571.1 - 7.2e-33 114.0 0.0 1e-32 113.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 TANGO2 PF05742.12 KKK17572.1 - 6e-72 242.7 0.0 6.9e-72 242.5 0.0 1.0 1 0 0 1 1 1 1 Transport and Golgi organisation 2 Ribosomal_L26 PF16906.5 KKK17574.1 - 3.3e-35 120.4 2.3 4.5e-35 120.0 2.3 1.2 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 KKK17574.1 - 2.1e-05 24.3 0.6 4.5e-05 23.2 0.6 1.5 1 0 0 1 1 1 1 KOW motif DUF1223 PF06764.11 KKK17574.1 - 0.12 12.4 0.0 0.15 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1223) EXS PF03124.14 KKK17575.1 - 6e-102 341.3 12.0 6.9e-102 341.2 12.0 1.0 1 0 0 1 1 1 1 EXS family Mucin PF01456.17 KKK17576.1 - 4.6e-06 26.7 27.5 4.6e-06 26.7 27.5 1.7 2 0 0 2 2 2 1 Mucin-like glycoprotein Dicty_REP PF05086.12 KKK17576.1 - 0.022 12.7 5.0 0.028 12.4 5.0 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF3357 PF11837.8 KKK17576.1 - 0.15 12.5 6.3 0.42 11.1 2.9 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) DUF4834 PF16118.5 KKK17576.1 - 1.2 10.2 6.5 0.85 10.6 0.8 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) SpoIIIAH PF12685.7 KKK17576.1 - 1.4 8.7 12.4 2 8.2 12.4 1.5 1 1 0 1 1 1 0 SpoIIIAH-like protein PI3K_1B_p101 PF10486.9 KKK17576.1 - 3.5 5.3 9.4 4.9 4.8 9.4 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Pex14_N PF04695.13 KKK17576.1 - 4 8.1 24.9 0.042 14.5 9.8 2.6 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region AAA_14 PF13173.6 KKK17577.1 - 0.0037 17.3 0.0 0.0071 16.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KKK17577.1 - 0.024 15.0 0.0 0.061 13.7 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.6 KKK17577.1 - 0.14 12.7 0.0 0.26 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.10 KKK17577.1 - 0.19 11.1 0.0 0.31 10.4 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 ATPase PF06745.13 KKK17577.1 - 0.21 10.9 0.0 0.32 10.3 0.0 1.2 1 0 0 1 1 1 0 KaiC Pex2_Pex12 PF04757.14 KKK17578.1 - 3.6e-46 157.6 8.1 4.7e-46 157.2 8.1 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.6 KKK17578.1 - 1.2e-11 44.2 9.2 2e-11 43.5 9.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KKK17578.1 - 3.4e-11 42.8 5.9 4.9e-11 42.3 5.9 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KKK17578.1 - 6.8e-11 42.3 10.2 1.1e-10 41.7 10.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KKK17578.1 - 1.7e-10 40.5 7.2 2.8e-10 39.9 7.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KKK17578.1 - 2.9e-09 36.8 3.6 2.9e-09 36.8 3.6 1.6 1 1 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 KKK17578.1 - 3e-08 33.4 6.6 5e-08 32.7 6.6 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KKK17578.1 - 1.9e-07 30.9 7.0 3.3e-07 30.2 7.0 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 KKK17578.1 - 3.4e-06 27.2 7.1 7.2e-06 26.2 7.1 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 KKK17578.1 - 8.3e-06 25.9 8.4 1.5e-05 25.0 8.4 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_10 PF16685.5 KKK17578.1 - 0.0042 17.2 6.3 0.0075 16.4 6.3 1.4 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-ANAPC11 PF12861.7 KKK17578.1 - 0.065 13.3 3.7 0.14 12.2 3.8 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 KKK17578.1 - 0.069 12.9 6.5 0.14 12.0 6.5 1.5 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.6 KKK17578.1 - 0.092 12.6 3.0 0.16 11.8 3.0 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein FYVE PF01363.21 KKK17578.1 - 1.7 8.9 6.9 6.4 7.0 7.0 1.9 1 1 0 1 1 1 0 FYVE zinc finger zf-RING_11 PF17123.5 KKK17578.1 - 3.1 7.6 7.8 0.79 9.5 4.1 2.0 2 0 0 2 2 2 0 RING-like zinc finger Rtf2 PF04641.12 KKK17578.1 - 6.9 6.0 6.5 0.5 9.7 1.6 1.7 2 0 0 2 2 2 0 Rtf2 RING-finger IBR PF01485.21 KKK17578.1 - 9.1 6.6 8.8 27 5.1 8.8 1.8 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain PRKCSH_1 PF13015.6 KKK17579.1 - 8.7e-33 113.2 0.6 1.3e-32 112.6 0.2 1.5 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.13 KKK17579.1 - 7.1e-11 43.0 0.1 1.5e-10 41.9 0.1 1.6 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein ATG27 PF09451.10 KKK17579.1 - 0.0087 15.9 0.1 0.012 15.5 0.1 1.2 1 0 0 1 1 1 1 Autophagy-related protein 27 YscO-like PF16789.5 KKK17579.1 - 0.012 15.7 0.2 0.019 15.0 0.2 1.2 1 0 0 1 1 1 0 YscO-like protein Cu_amine_oxid PF01179.20 KKK17580.1 - 2.2e-164 547.2 1.1 2.7e-164 547.0 1.1 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.16 KKK17580.1 - 7.9e-05 22.8 0.0 0.00015 21.9 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Cu_amine_oxidN3 PF02728.16 KKK17580.1 - 0.014 15.8 0.0 0.03 14.7 0.0 1.5 1 0 0 1 1 1 0 Copper amine oxidase, N3 domain CMAS PF02353.20 KKK17581.1 - 1.3e-62 211.6 0.1 1.7e-62 211.2 0.1 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 KKK17581.1 - 1e-08 35.8 0.0 2.2e-08 34.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KKK17581.1 - 2.7e-08 33.8 0.0 4.5e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KKK17581.1 - 1.1e-07 32.4 0.0 2.1e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KKK17581.1 - 0.00099 19.8 0.0 0.0019 18.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.13 KKK17581.1 - 0.011 15.3 0.0 0.021 14.4 0.0 1.4 1 0 0 1 1 1 0 Histone methylation protein DOT1 MTS PF05175.14 KKK17581.1 - 0.024 14.2 0.0 0.039 13.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain N6_N4_Mtase PF01555.18 KKK17581.1 - 0.065 12.9 0.0 8.2 6.1 0.0 2.4 2 0 0 2 2 2 0 DNA methylase FtsJ PF01728.19 KKK17581.1 - 0.17 12.0 0.0 0.27 11.3 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase PCMT PF01135.19 KKK17581.1 - 0.17 11.6 0.0 0.26 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 KKK17581.1 - 0.2 11.4 0.0 0.41 10.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Tropomyosin_1 PF12718.7 KKK17583.1 - 5.9e-45 152.9 28.3 2.7e-30 105.4 17.8 2.0 2 0 0 2 2 2 2 Tropomyosin like Tropomyosin PF00261.20 KKK17583.1 - 7.7e-08 32.0 25.9 0.002 17.5 1.0 2.9 2 1 1 3 3 3 3 Tropomyosin KLRAQ PF10205.9 KKK17583.1 - 0.00011 22.4 17.1 0.00014 22.1 12.3 2.7 2 1 1 3 3 3 1 Predicted coiled-coil domain-containing protein Striatin PF08232.12 KKK17583.1 - 0.006 17.2 11.5 0.099 13.2 3.6 2.2 2 0 0 2 2 2 2 Striatin family FlaC_arch PF05377.11 KKK17583.1 - 0.013 15.9 11.4 3.2 8.2 0.4 3.7 2 1 2 4 4 4 0 Flagella accessory protein C (FlaC) DUF3450 PF11932.8 KKK17583.1 - 0.013 14.8 17.0 0.2 10.9 0.1 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF3450) Spc7 PF08317.11 KKK17583.1 - 0.017 14.1 21.7 0.27 10.1 12.4 2.3 2 1 0 2 2 2 0 Spc7 kinetochore protein BST2 PF16716.5 KKK17583.1 - 0.023 15.3 23.8 0.043 14.4 0.5 3.8 2 1 2 4 4 4 0 Bone marrow stromal antigen 2 bZIP_1 PF00170.21 KKK17583.1 - 0.025 14.6 22.4 0.89 9.7 1.8 4.1 2 1 2 4 4 4 0 bZIP transcription factor DUF842 PF05811.13 KKK17583.1 - 0.029 14.1 5.2 0.028 14.1 1.8 2.3 2 1 0 2 2 2 0 Eukaryotic protein of unknown function (DUF842) TMF_TATA_bd PF12325.8 KKK17583.1 - 0.032 14.4 21.1 0.22 11.7 14.2 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding APG6_N PF17675.1 KKK17583.1 - 0.033 14.7 0.5 0.033 14.7 0.5 2.6 2 1 0 2 2 2 0 Apg6 coiled-coil region GAS PF13851.6 KKK17583.1 - 0.049 13.0 21.4 0.21 10.9 12.6 2.2 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Sipho_Gp157 PF05565.11 KKK17583.1 - 0.05 13.6 15.1 1.7 8.6 9.9 2.7 2 1 0 2 2 2 0 Siphovirus Gp157 Jnk-SapK_ap_N PF09744.9 KKK17583.1 - 0.052 13.8 22.0 0.1 12.9 1.8 2.4 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 TMF_DNA_bd PF12329.8 KKK17583.1 - 0.059 13.4 27.6 0.046 13.7 13.1 3.2 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding DUF4482 PF14818.6 KKK17583.1 - 0.062 14.2 1.0 0.062 14.2 1.0 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4482) MAD PF05557.13 KKK17583.1 - 0.07 11.5 18.8 0.16 10.3 11.4 2.0 2 0 0 2 2 2 0 Mitotic checkpoint protein TACC_C PF05010.14 KKK17583.1 - 0.086 12.6 20.2 0.35 10.6 1.0 2.4 2 1 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal ADIP PF11559.8 KKK17583.1 - 0.088 12.9 19.9 1.5 8.9 14.8 2.6 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding Ax_dynein_light PF10211.9 KKK17583.1 - 0.1 12.5 0.3 0.1 12.5 0.3 2.8 1 1 1 2 2 2 0 Axonemal dynein light chain YabA PF06156.13 KKK17583.1 - 0.11 13.2 13.4 0.32 11.6 7.7 2.4 2 0 0 2 2 2 0 Initiation control protein YabA CENP-H PF05837.12 KKK17583.1 - 0.11 12.9 16.2 3.4 8.1 10.5 2.4 2 0 0 2 2 2 0 Centromere protein H (CENP-H) Transketolase_N PF00456.21 KKK17583.1 - 0.12 11.3 0.8 0.23 10.4 0.8 1.4 1 0 0 1 1 1 0 Transketolase, thiamine diphosphate binding domain Vps16_C PF04840.12 KKK17583.1 - 0.12 11.4 4.8 0.028 13.5 1.8 1.5 2 0 0 2 2 1 0 Vps16, C-terminal region SOGA PF11365.8 KKK17583.1 - 0.12 13.5 17.3 1.6 9.9 4.1 3.3 3 0 0 3 3 3 0 Protein SOGA SlyX PF04102.12 KKK17583.1 - 0.14 12.8 19.4 0.55 10.9 5.7 3.2 2 1 1 3 3 3 0 SlyX ATG16 PF08614.11 KKK17583.1 - 0.14 12.4 24.7 1.1 9.5 16.8 2.1 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) TMPIT PF07851.13 KKK17583.1 - 0.17 11.1 13.0 1.6 7.9 0.2 2.0 2 0 0 2 2 2 0 TMPIT-like protein MbeD_MobD PF04899.12 KKK17583.1 - 0.17 12.0 7.3 0.43 10.7 0.5 2.8 2 1 1 3 3 2 0 MbeD/MobD like HAUS-augmin3 PF14932.6 KKK17583.1 - 0.22 11.1 16.8 0.87 9.1 1.0 2.1 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 Ctf8 PF09696.10 KKK17583.1 - 0.24 11.8 4.7 0.85 10.0 4.7 1.9 1 1 0 1 1 1 0 Ctf8 DUF724 PF05266.14 KKK17583.1 - 0.24 11.2 16.1 0.83 9.5 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Uso1_p115_C PF04871.13 KKK17583.1 - 0.3 11.5 28.2 0.49 10.8 2.0 2.5 2 1 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region BLOC1_2 PF10046.9 KKK17583.1 - 0.35 11.2 15.4 0.57 10.5 0.4 3.0 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 HMMR_C PF15908.5 KKK17583.1 - 0.38 11.0 11.9 1.2 9.4 0.7 2.2 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor C-terminal Atg14 PF10186.9 KKK17583.1 - 0.44 9.6 12.5 0.13 11.4 7.2 2.0 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Laminin_II PF06009.12 KKK17583.1 - 0.47 10.5 11.4 2.9 7.9 0.3 2.2 2 0 0 2 2 2 0 Laminin Domain II DUF2461 PF09365.10 KKK17583.1 - 0.48 10.3 3.5 0.45 10.4 0.3 2.0 2 0 0 2 2 2 0 Conserved hypothetical protein (DUF2461) KASH_CCD PF14662.6 KKK17583.1 - 0.51 10.1 23.4 0.88 9.4 0.3 2.7 2 1 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH 5_nucleotid PF05761.14 KKK17583.1 - 0.53 9.1 9.2 0.19 10.6 3.6 1.9 2 0 0 2 2 2 0 5' nucleotidase family FapA PF03961.13 KKK17583.1 - 0.54 8.8 11.3 2.4 6.6 6.4 2.0 2 0 0 2 2 2 0 Flagellar Assembly Protein A ZapB PF06005.12 KKK17583.1 - 0.56 10.7 28.6 5.2 7.6 5.0 3.6 2 2 1 3 3 3 0 Cell division protein ZapB Dynamitin PF04912.14 KKK17583.1 - 0.61 9.4 18.4 5.2 6.3 13.1 2.4 2 1 0 2 2 2 0 Dynamitin Mod_r PF07200.13 KKK17583.1 - 0.65 10.1 19.0 3.8 7.6 11.9 2.1 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DUF465 PF04325.13 KKK17583.1 - 0.67 10.0 8.4 0.54 10.3 0.2 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF465) DivIC PF04977.15 KKK17583.1 - 0.77 9.6 24.8 0.11 12.3 4.5 3.8 2 1 2 4 4 4 0 Septum formation initiator UPF0242 PF06785.11 KKK17583.1 - 0.89 9.6 18.6 3 7.9 13.5 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF2188 PF09954.9 KKK17583.1 - 0.94 9.7 3.7 1.5 9.0 0.6 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2188) Syntaxin-6_N PF09177.11 KKK17583.1 - 1 10.0 15.7 1.4 9.5 0.5 2.4 2 0 0 2 2 2 0 Syntaxin 6, N-terminal CALCOCO1 PF07888.11 KKK17583.1 - 1 8.2 21.1 0.52 9.1 1.9 2.2 2 0 0 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like TPR_MLP1_2 PF07926.12 KKK17583.1 - 1 9.4 30.3 0.87 9.7 10.3 3.1 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein AAA_13 PF13166.6 KKK17583.1 - 1.1 7.9 15.3 2 7.0 0.4 2.1 2 0 0 2 2 2 0 AAA domain Fez1 PF06818.15 KKK17583.1 - 1.1 9.7 20.1 4.6 7.6 19.9 1.8 1 1 0 1 1 1 0 Fez1 ERM PF00769.19 KKK17583.1 - 1.1 9.0 27.0 6.3 6.5 27.0 1.9 1 1 0 1 1 1 0 Ezrin/radixin/moesin family YbaB_DNA_bd PF02575.16 KKK17583.1 - 1.2 9.5 13.2 4.6 7.5 0.1 3.3 2 1 0 2 2 2 0 YbaB/EbfC DNA-binding family CLZ PF16526.5 KKK17583.1 - 1.2 9.5 21.6 3 8.3 0.6 3.4 2 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels FAM76 PF16046.5 KKK17583.1 - 1.3 8.3 14.8 1.3 8.3 8.3 2.2 2 0 0 2 2 2 0 FAM76 protein DUF5082 PF16888.5 KKK17583.1 - 1.5 9.2 18.5 13 6.1 0.5 3.2 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) DUF4618 PF15397.6 KKK17583.1 - 1.5 8.2 17.8 0.17 11.3 0.8 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4618) DUF641 PF04859.12 KKK17583.1 - 1.6 9.1 14.2 0.49 10.7 5.1 2.8 2 1 1 3 3 3 0 Plant protein of unknown function (DUF641) Fmp27_WPPW PF10359.9 KKK17583.1 - 1.7 7.4 14.0 1.6 7.5 7.1 2.1 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain bZIP_2 PF07716.15 KKK17583.1 - 2.2 8.4 24.8 0.42 10.7 1.0 4.6 3 2 2 5 5 4 0 Basic region leucine zipper LPD39 PF18858.1 KKK17583.1 - 2.4 8.2 14.3 0.87 9.6 0.3 2.1 2 0 0 2 2 2 0 Large polyvalent protein associated domain 39 DUF2721 PF11026.8 KKK17583.1 - 2.6 7.9 5.4 1.6 8.7 1.6 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF2721) BRE1 PF08647.11 KKK17583.1 - 2.8 8.1 23.0 5.1 7.2 1.1 2.2 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase DUF4200 PF13863.6 KKK17583.1 - 2.9 8.3 24.6 0.44 11.0 0.8 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4200) DUF812 PF05667.11 KKK17583.1 - 3.1 6.6 19.3 3.6 6.4 12.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF812) XhlA PF10779.9 KKK17583.1 - 3.1 8.0 15.6 5.8 7.2 0.2 3.4 2 1 1 3 3 3 0 Haemolysin XhlA Herpes_UL6 PF01763.16 KKK17583.1 - 3.3 6.1 9.3 1.1 7.7 4.7 1.9 2 0 0 2 2 2 0 Herpesvirus UL6 like DUF1640 PF07798.11 KKK17583.1 - 3.4 7.7 16.5 18 5.3 16.5 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) FmiP_Thoc5 PF09766.9 KKK17583.1 - 3.8 6.7 14.8 9.5 5.4 0.3 2.1 2 0 0 2 2 2 0 Fms-interacting protein/Thoc5 DUF4407 PF14362.6 KKK17583.1 - 4.3 6.6 19.0 3e+02 0.6 19.0 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) MCU PF04678.13 KKK17583.1 - 4.4 7.4 12.5 1 9.5 5.1 2.3 1 1 1 2 2 2 0 Mitochondrial calcium uniporter Nup54 PF13874.6 KKK17583.1 - 5.3 7.1 16.0 5.4 7.1 9.7 2.1 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 Lipoprotein_2 PF00921.17 KKK17583.1 - 5.9 6.3 10.6 0.69 9.4 6.6 1.4 2 0 0 2 2 1 0 Borrelia lipoprotein DUF4795 PF16043.5 KKK17583.1 - 7.4 6.1 18.4 86 2.6 18.4 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) Med4 PF10018.9 KKK17583.1 - 7.4 6.2 13.3 0.65 9.6 7.4 2.0 2 0 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 DUF2730 PF10805.8 KKK17583.1 - 7.4 6.7 10.3 18 5.5 5.1 2.9 2 2 0 2 2 2 0 Protein of unknown function (DUF2730) DUF5320 PF17253.2 KKK17583.1 - 7.6 7.7 16.5 12 7.0 3.4 3.2 2 1 1 3 3 3 0 Family of unknown function (DUF5320) Seryl_tRNA_N PF02403.22 KKK17583.1 - 8 6.7 18.3 9.6 6.5 0.2 2.7 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain HAUS6_N PF14661.6 KKK17583.1 - 8.4 5.9 15.3 0.87 9.1 1.1 2.3 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus LCD1 PF09798.9 KKK17583.1 - 8.6 4.7 14.2 23 3.4 14.2 1.6 1 1 0 1 1 1 0 DNA damage checkpoint protein DUF4472 PF14739.6 KKK17583.1 - 8.8 7.1 22.1 4.3 8.1 1.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4472) CENP-F_leu_zip PF10473.9 KKK17583.1 - 8.8 6.4 26.0 0.9 9.6 0.7 2.6 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF5595 PF18077.1 KKK17583.1 - 9 6.5 17.2 0.96 9.6 4.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF5595) Phage_GPO PF05929.11 KKK17583.1 - 9.9 5.7 13.7 3.8 7.1 8.0 2.0 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase PAP_assoc PF03828.19 KKK17584.1 - 2.9e-15 56.2 0.3 6e-15 55.2 0.3 1.6 1 0 0 1 1 1 1 Cid1 family poly A polymerase GFA PF04828.14 KKK17584.1 - 2.7e-11 43.6 4.9 1.1e-08 35.3 0.7 2.6 2 0 0 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme NTP_transf_2 PF01909.23 KKK17584.1 - 2.1e-10 40.7 0.0 7.1e-10 39.0 0.0 1.9 2 0 0 2 2 2 1 Nucleotidyltransferase domain Mito_fiss_reg PF05308.11 KKK17584.1 - 0.19 11.8 16.7 0.17 11.9 9.2 2.3 2 0 0 2 2 2 0 Mitochondrial fission regulator Pam16 PF03656.13 KKK17585.1 - 3.8e-35 120.7 0.5 4.7e-35 120.4 0.5 1.0 1 0 0 1 1 1 1 Pam16 Pex24p PF06398.11 KKK17586.1 - 4.9e-100 335.1 0.7 7e-100 334.6 0.7 1.2 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Fungal_trans_2 PF11951.8 KKK17587.1 - 4.5e-48 164.0 0.3 9.8e-48 162.9 0.1 1.6 1 1 1 2 2 2 1 Fungal specific transcription factor domain Nop25 PF09805.9 KKK17588.1 - 5.6e-35 120.8 22.8 5.6e-35 120.8 22.8 3.0 2 1 1 3 3 3 1 Nucleolar protein 12 (25kDa) BUD22 PF09073.10 KKK17588.1 - 0.07 12.5 38.9 0.093 12.1 38.9 1.2 1 0 0 1 1 1 0 BUD22 Herpes_DNAp_acc PF04929.12 KKK17588.1 - 0.93 8.4 16.0 1.3 7.9 16.0 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor ATP-synt_S1 PF05827.12 KKK17589.1 - 0.0024 17.7 0.0 0.0041 17.0 0.0 1.4 1 0 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) Nuc_recep-AF1 PF11825.8 KKK17589.1 - 0.011 15.8 0.1 0.019 15.0 0.1 1.4 1 0 0 1 1 1 0 Nuclear/hormone receptor activator site AF-1 MFS_1 PF07690.16 KKK17591.1 - 6.9e-31 107.5 44.8 6.9e-31 107.5 44.8 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KKK17591.1 - 3e-09 36.3 41.1 4.1e-08 32.5 13.0 2.3 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KKK17592.1 - 1e-21 77.3 9.7 1.5e-21 76.7 9.7 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KKK17592.1 - 2.8e-16 59.5 1.7 3.8e-16 59.0 1.7 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter Hydrolase_4 PF12146.8 KKK17598.1 - 6.1e-21 74.8 0.0 1.4e-14 54.0 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KKK17598.1 - 3.3e-12 46.6 0.1 9e-09 35.3 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KKK17598.1 - 2.3e-07 31.6 0.0 4.2e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.12 KKK17598.1 - 3.9e-07 29.0 0.2 0.033 12.9 0.1 3.0 2 1 1 3 3 3 2 Acetyl xylan esterase (AXE1) Peptidase_S9 PF00326.21 KKK17598.1 - 1.4e-05 24.7 0.0 0.18 11.3 0.0 2.4 2 0 0 2 2 2 2 Prolyl oligopeptidase family FSH1 PF03959.13 KKK17598.1 - 2.7e-05 23.9 0.0 0.0001 22.1 0.0 1.9 2 1 0 2 2 2 1 Serine hydrolase (FSH1) BAAT_C PF08840.11 KKK17598.1 - 0.00021 21.3 0.0 0.017 15.1 0.0 2.3 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_3 PF07859.13 KKK17598.1 - 0.00063 19.7 0.0 0.0011 18.9 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.18 KKK17598.1 - 0.00093 18.8 0.0 0.18 11.4 0.0 2.3 2 0 0 2 2 2 1 Dienelactone hydrolase family Peptidase_S15 PF02129.18 KKK17598.1 - 0.0066 16.1 0.0 1.7 8.2 0.0 2.2 2 0 0 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) Esterase PF00756.20 KKK17598.1 - 0.0093 15.6 0.0 0.019 14.6 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Abhydrolase_2 PF02230.16 KKK17598.1 - 0.012 15.5 0.0 0.96 9.2 0.0 2.3 1 1 1 2 2 2 0 Phospholipase/Carboxylesterase PGAP1 PF07819.13 KKK17598.1 - 0.023 14.4 0.2 0.41 10.3 0.2 2.2 1 1 0 1 1 1 0 PGAP1-like protein DUF818 PF05677.12 KKK17598.1 - 0.025 13.6 0.0 0.036 13.0 0.0 1.1 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) LIDHydrolase PF10230.9 KKK17598.1 - 0.028 14.0 0.0 0.46 10.0 0.0 2.0 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase Lipase_3 PF01764.25 KKK17598.1 - 0.064 13.1 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) DUF2974 PF11187.8 KKK17598.1 - 0.084 12.4 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Abhydrolase_5 PF12695.7 KKK17598.1 - 0.15 11.8 0.0 0.36 10.6 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Proteasome PF00227.26 KKK17599.1 - 2.3e-48 164.2 0.2 2.6e-48 164.0 0.2 1.0 1 0 0 1 1 1 1 Proteasome subunit Cyclin PF08613.11 KKK17600.1 - 4.2e-38 131.3 10.9 3.2e-24 86.1 0.1 3.4 3 1 0 3 3 3 2 Cyclin Orthopox_A5L PF06193.11 KKK17600.1 - 1.8 7.9 9.4 0.085 12.3 1.9 2.4 3 0 0 3 3 3 0 Orthopoxvirus A5L protein-like RabGAP-TBC PF00566.18 KKK17602.1 - 7.6e-27 94.4 0.0 1.2e-26 93.7 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain SBE2 PF17076.5 KKK17602.1 - 3.7e-07 28.8 1.1 3.7e-07 28.8 1.1 2.1 2 0 0 2 2 2 2 SBE2, cell-wall formation Synaphin PF05835.12 KKK17602.1 - 0.089 13.1 3.5 0.2 12.0 3.5 1.5 1 0 0 1 1 1 0 Synaphin protein Metal_resist PF13801.6 KKK17602.1 - 0.53 10.5 3.8 14 5.9 2.1 3.2 2 0 0 2 2 2 0 Heavy-metal resistance Telomerase_RBD PF12009.8 KKK17603.1 - 3.5e-46 156.6 0.0 9.7e-46 155.2 0.1 1.8 2 0 0 2 2 2 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.27 KKK17603.1 - 2.5e-12 46.8 0.0 5.1e-08 32.7 0.0 2.3 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RhoGAP PF00620.27 KKK17604.1 - 2.8e-30 105.2 0.0 4.6e-30 104.4 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain FXMR_C2 PF16098.5 KKK17604.1 - 0.015 15.7 2.0 0.015 15.7 2.0 2.2 2 0 0 2 2 2 0 Fragile X-related mental retardation protein C-terminal region 2 MutS_V PF00488.21 KKK17606.1 - 1.7e-72 243.5 0.2 4.6e-72 242.0 0.2 1.8 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KKK17606.1 - 3.9e-37 128.3 0.7 9.3e-37 127.1 0.7 1.7 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 KKK17606.1 - 1.5e-29 102.5 0.0 4.1e-29 101.1 0.0 1.8 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 KKK17606.1 - 6.4e-10 39.4 0.0 2e-09 37.8 0.0 2.0 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 KKK17606.1 - 0.00051 20.3 0.1 0.0014 18.9 0.1 1.8 1 0 0 1 1 1 1 MutS family domain IV DUF4911 PF16256.5 KKK17606.1 - 0.012 15.5 0.2 0.04 13.9 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4911) FANCI_S2 PF14676.6 KKK17606.1 - 0.14 12.4 0.3 0.33 11.2 0.3 1.5 1 0 0 1 1 1 0 FANCI solenoid 2 CAP_N PF01213.19 KKK17607.1 - 0.038 13.5 8.7 0.21 11.1 8.0 2.0 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal PRIMA1 PF16101.5 KKK17607.1 - 0.078 13.0 11.3 0.18 11.8 11.3 1.6 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 cEGF PF12662.7 KKK17607.1 - 7.5 6.6 8.0 11 6.0 0.1 2.6 2 0 0 2 2 2 0 Complement Clr-like EGF-like DAP3 PF10236.9 KKK17609.1 - 3.7e-110 367.9 0.0 4.7e-110 367.6 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 T2SSE PF00437.20 KKK17609.1 - 0.00043 19.4 0.0 0.00072 18.7 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_16 PF13191.6 KKK17609.1 - 0.011 16.2 0.0 0.02 15.3 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_14 PF13173.6 KKK17609.1 - 0.036 14.1 0.0 0.061 13.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain RRS1 PF04939.12 KKK17610.1 - 5e-58 195.5 1.9 6e-58 195.3 1.9 1.1 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) Sel1 PF08238.12 KKK17611.1 - 6e-11 42.7 5.1 2.1e-07 31.4 0.0 3.9 4 0 0 4 4 4 2 Sel1 repeat Laminin_I PF06008.14 KKK17612.1 - 0.00098 18.9 4.6 0.0013 18.6 4.6 1.2 1 0 0 1 1 1 1 Laminin Domain I Vps51 PF08700.11 KKK17612.1 - 0.00098 19.2 0.6 0.6 10.2 0.2 2.3 2 0 0 2 2 2 2 Vps51/Vps67 EzrA PF06160.12 KKK17612.1 - 0.0015 16.8 1.3 0.0019 16.5 1.3 1.2 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA DivIC PF04977.15 KKK17612.1 - 0.0025 17.5 5.6 0.0066 16.2 1.0 2.4 2 0 0 2 2 2 1 Septum formation initiator TBPIP PF07106.13 KKK17612.1 - 0.0065 16.4 0.0 0.013 15.4 0.0 1.5 1 0 0 1 1 1 1 TBPIP/Hop2 winged helix domain DUF3381 PF11861.8 KKK17612.1 - 0.033 14.0 1.5 0.033 14.0 1.5 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) Apt1 PF10351.9 KKK17612.1 - 0.034 13.0 2.1 0.042 12.7 2.1 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF5082 PF16888.5 KKK17612.1 - 0.044 14.1 1.6 0.075 13.3 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) TMCO5 PF14992.6 KKK17612.1 - 0.046 13.3 3.3 0.11 12.1 2.4 1.9 2 0 0 2 2 2 0 TMCO5 family Miff PF05644.11 KKK17612.1 - 0.047 13.3 1.7 0.048 13.3 0.9 1.4 1 1 0 1 1 1 0 Mitochondrial and peroxisomal fission factor Mff V_ATPase_I PF01496.19 KKK17612.1 - 0.11 10.5 0.6 0.12 10.3 0.6 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Seryl_tRNA_N PF02403.22 KKK17612.1 - 0.13 12.5 5.3 0.2 11.9 5.3 1.5 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF4140 PF13600.6 KKK17612.1 - 0.14 12.6 9.6 0.081 13.4 3.4 2.7 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) DUF1690 PF07956.11 KKK17612.1 - 0.24 11.8 6.9 0.41 11.1 6.7 1.6 1 1 0 1 1 1 0 Protein of Unknown function (DUF1690) DUF4337 PF14235.6 KKK17612.1 - 0.31 11.1 4.3 6.6 6.8 1.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) FlxA PF14282.6 KKK17612.1 - 0.41 10.7 6.7 1.6 8.8 6.7 2.0 1 1 0 1 1 1 0 FlxA-like protein APG6_N PF17675.1 KKK17612.1 - 0.65 10.5 12.4 2.5 8.6 12.3 2.0 1 1 0 1 1 1 0 Apg6 coiled-coil region SlyX PF04102.12 KKK17612.1 - 0.99 10.1 7.5 0.41 11.3 3.2 2.5 2 1 0 2 2 2 0 SlyX ZapB PF06005.12 KKK17612.1 - 1.4 9.4 10.6 2 8.9 4.4 2.5 1 1 1 2 2 2 0 Cell division protein ZapB OmpH PF03938.14 KKK17612.1 - 1.6 9.1 7.7 2.7 8.3 7.7 1.5 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Uso1_p115_C PF04871.13 KKK17612.1 - 1.9 8.9 13.3 1.3 9.4 6.8 2.1 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region LPP PF04728.13 KKK17612.1 - 2.8 8.4 5.6 14 6.2 0.6 2.5 2 0 0 2 2 2 0 Lipoprotein leucine-zipper Prenyltrans PF00432.21 KKK17613.1 - 9.3e-53 175.6 10.4 7.1e-12 44.9 0.0 6.2 6 0 0 6 6 6 6 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 KKK17613.1 - 0.00055 19.1 0.0 0.19 10.8 0.0 3.2 3 1 0 3 3 3 2 Squalene-hopene cyclase N-terminal domain SQHop_cyclase_C PF13243.6 KKK17613.1 - 0.0016 17.6 0.0 0.16 11.0 0.0 2.6 1 1 1 2 2 2 2 Squalene-hopene cyclase C-terminal domain RhoGEF PF00621.20 KKK17614.1 - 9e-35 120.6 0.0 2e-34 119.4 0.0 1.6 1 0 0 1 1 1 1 RhoGEF domain BAR PF03114.18 KKK17614.1 - 1.9e-11 44.1 1.0 5.1e-11 42.7 1.0 1.7 1 0 0 1 1 1 1 BAR domain Peptidase_C48 PF02902.19 KKK17614.1 - 3.2e-05 23.9 0.1 0.00041 20.2 0.1 2.3 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain DUF676 PF05057.14 KKK17615.1 - 0.077 12.5 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Hydrolase_4 PF12146.8 KKK17615.1 - 0.085 12.1 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 LCAT PF02450.15 KKK17615.1 - 0.25 10.4 0.0 0.55 9.3 0.0 1.5 2 0 0 2 2 2 0 Lecithin:cholesterol acyltransferase Peptidase_S9 PF00326.21 KKK17615.1 - 0.25 10.8 0.0 0.43 10.0 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family GLE1 PF07817.13 KKK17628.1 - 1.4e-36 126.0 0.0 1.1e-27 96.9 0.0 2.6 1 1 1 2 2 2 2 GLE1-like protein MMgT PF10270.9 KKK17629.1 - 2.2e-35 121.0 0.0 2.5e-35 120.8 0.0 1.0 1 0 0 1 1 1 1 Membrane magnesium transporter EF1_GNE PF00736.19 KKK17630.1 - 2.5e-31 107.7 3.2 4e-31 107.0 3.2 1.3 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.9 KKK17630.1 - 1.6e-11 44.4 4.5 1.6e-11 44.4 4.5 2.6 3 0 0 3 3 3 1 Eukaryotic elongation factor 1 beta central acidic region GST_C_3 PF14497.6 KKK17630.1 - 0.00088 19.4 0.4 0.0018 18.4 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KKK17630.1 - 0.0038 17.4 1.5 0.0077 16.4 0.1 2.3 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KKK17630.1 - 0.021 14.9 0.2 0.53 10.3 0.2 2.5 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain AAA_2 PF07724.14 KKK17631.1 - 3.4e-46 157.5 0.0 3.6e-44 150.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 KKK17631.1 - 5.8e-35 119.3 1.0 5.8e-35 119.3 1.0 2.6 1 1 1 2 2 2 1 AAA lid domain ClpB_D2-small PF10431.9 KKK17631.1 - 1.3e-26 92.4 0.2 4.6e-26 90.7 0.2 2.0 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 KKK17631.1 - 4.6e-19 69.2 0.0 3.2e-10 40.5 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KKK17631.1 - 3.1e-13 49.9 1.0 2.2e-08 34.2 0.0 3.3 4 1 0 4 4 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KKK17631.1 - 3.6e-09 37.2 8.7 0.00013 22.3 0.2 4.4 3 2 1 4 4 4 2 AAA ATPase domain Sigma54_activat PF00158.26 KKK17631.1 - 1.4e-08 34.6 0.4 9.3e-05 22.2 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_22 PF13401.6 KKK17631.1 - 3.8e-08 33.7 2.4 0.0074 16.6 0.0 3.7 3 2 0 3 3 3 2 AAA domain TniB PF05621.11 KKK17631.1 - 7.3e-06 25.5 0.0 0.012 15.0 0.0 3.6 3 1 0 3 3 2 1 Bacterial TniB protein AAA_7 PF12775.7 KKK17631.1 - 1.4e-05 24.7 0.0 0.031 13.8 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region ATPase_2 PF01637.18 KKK17631.1 - 1.6e-05 24.9 4.2 2.4 8.0 0.0 4.3 3 2 1 4 4 4 2 ATPase domain predominantly from Archaea AAA_14 PF13173.6 KKK17631.1 - 1.7e-05 24.8 0.0 0.23 11.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 KKK17631.1 - 1.8e-05 24.7 0.0 0.094 12.6 0.0 2.5 2 0 0 2 2 2 2 NACHT domain IstB_IS21 PF01695.17 KKK17631.1 - 0.00014 21.6 0.0 0.76 9.5 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_18 PF13238.6 KKK17631.1 - 0.00016 22.2 0.8 0.66 10.5 0.0 3.3 3 0 0 3 3 2 2 AAA domain SRP54 PF00448.22 KKK17631.1 - 0.00032 20.4 0.1 0.059 13.0 0.0 2.5 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_24 PF13479.6 KKK17631.1 - 0.00034 20.4 0.0 0.33 10.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 KKK17631.1 - 0.00053 20.3 4.7 0.056 13.7 0.0 3.9 4 1 0 4 4 3 1 AAA domain AAA_30 PF13604.6 KKK17631.1 - 0.00093 19.0 1.3 0.095 12.4 0.0 3.6 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.22 KKK17631.1 - 0.00095 19.5 0.0 0.74 10.2 0.0 2.8 2 1 0 2 2 2 1 RNA helicase AAA_19 PF13245.6 KKK17631.1 - 0.0013 19.1 0.5 0.14 12.5 0.1 3.1 2 1 0 2 2 2 1 AAA domain ResIII PF04851.15 KKK17631.1 - 0.0018 18.3 0.0 4.6 7.2 0.0 3.2 3 0 0 3 3 2 0 Type III restriction enzyme, res subunit Mg_chelatase PF01078.21 KKK17631.1 - 0.0024 17.3 0.1 2.5 7.4 0.1 3.1 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI TsaE PF02367.17 KKK17631.1 - 0.0027 17.7 0.1 2.4 8.2 0.0 2.7 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 KKK17631.1 - 0.0031 18.0 1.1 2 8.9 0.0 3.3 3 0 0 3 3 3 1 ABC transporter TrwB_AAD_bind PF10412.9 KKK17631.1 - 0.0046 15.9 0.1 0.27 10.1 0.1 2.4 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain Zeta_toxin PF06414.12 KKK17631.1 - 0.0047 16.2 0.0 0.66 9.2 0.0 2.7 2 0 0 2 2 2 1 Zeta toxin Roc PF08477.13 KKK17631.1 - 0.0055 16.9 0.0 0.71 10.1 0.0 2.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase DUF853 PF05872.12 KKK17631.1 - 0.0081 14.8 0.1 0.072 11.7 0.1 2.3 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF853) DUF815 PF05673.13 KKK17631.1 - 0.0093 15.1 0.1 0.48 9.5 0.1 2.9 2 1 0 2 2 2 1 Protein of unknown function (DUF815) RsgA_GTPase PF03193.16 KKK17631.1 - 0.0099 15.8 0.7 2.3 8.1 0.0 2.7 3 0 0 3 3 2 1 RsgA GTPase ATP_bind_1 PF03029.17 KKK17631.1 - 0.013 15.3 0.1 0.24 11.2 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein PduV-EutP PF10662.9 KKK17631.1 - 0.013 15.3 0.0 0.55 10.0 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NTPase_1 PF03266.15 KKK17631.1 - 0.031 14.2 0.1 0.39 10.6 0.0 2.5 2 0 0 2 2 2 0 NTPase RuvB_N PF05496.12 KKK17631.1 - 0.039 13.7 0.2 9.3 6.0 0.0 3.8 4 0 0 4 4 4 0 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 KKK17631.1 - 0.046 13.9 3.0 5.3 7.2 0.0 3.0 3 0 0 3 3 2 0 AAA domain AAA_21 PF13304.6 KKK17631.1 - 0.059 13.2 1.0 0.87 9.3 0.0 3.0 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 KKK17631.1 - 0.078 12.5 0.1 1.5 8.3 0.0 2.8 2 0 0 2 2 2 0 AAA domain DNA_pol3_delta2 PF13177.6 KKK17631.1 - 0.08 12.7 0.1 5.1 6.9 0.0 2.7 2 0 0 2 2 2 0 DNA polymerase III, delta subunit AAA_6 PF12774.7 KKK17631.1 - 0.096 11.6 0.1 2.7 6.9 0.0 2.3 2 0 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region UvrD-helicase PF00580.21 KKK17631.1 - 0.12 11.9 5.2 0.32 10.5 0.1 2.2 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain AAA_23 PF13476.6 KKK17631.1 - 0.24 11.9 12.0 2.8 8.4 5.6 3.7 4 0 0 4 4 3 0 AAA domain Zw10 PF06248.13 KKK17631.1 - 0.45 9.0 3.1 0.73 8.3 3.1 1.2 1 0 0 1 1 1 0 Centromere/kinetochore Zw10 GAS PF13851.6 KKK17631.1 - 0.72 9.2 12.8 1.5 8.1 12.8 1.5 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DivIC PF04977.15 KKK17631.1 - 1.1 9.1 14.2 1.3 8.8 10.1 2.5 1 1 1 2 2 2 0 Septum formation initiator UPF0242 PF06785.11 KKK17631.1 - 2.5 8.2 12.2 5.6 7.0 12.2 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Prefoldin_2 PF01920.20 KKK17631.1 - 4.1 7.4 13.1 4.4 7.3 3.7 2.9 1 1 1 2 2 2 0 Prefoldin subunit GrpE PF01025.19 KKK17631.1 - 4.3 7.0 12.3 11 5.7 12.3 1.7 1 0 0 1 1 1 0 GrpE DUF4407 PF14362.6 KKK17631.1 - 6.3 6.1 10.4 11 5.2 10.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) MutS_V PF00488.21 KKK17632.1 - 1.9e-26 93.2 0.2 5.3e-26 91.8 0.1 1.7 2 0 0 2 2 2 1 MutS domain V MutS_III PF05192.18 KKK17632.1 - 2.7e-17 63.6 0.1 8.7e-17 62.0 0.0 1.9 2 0 0 2 2 2 1 MutS domain III MutS_IV PF05190.18 KKK17632.1 - 0.0089 16.4 0.0 0.03 14.7 0.0 1.9 2 0 0 2 2 2 1 MutS family domain IV Sas10 PF09368.10 KKK17633.1 - 6.7e-30 103.4 8.0 6.7e-30 103.4 8.0 3.4 3 0 0 3 3 3 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.15 KKK17633.1 - 8.6e-13 48.7 1.2 5.5e-12 46.1 0.0 2.9 2 0 0 2 2 2 1 Sas10/Utp3/C1D family DUF778 PF05608.12 KKK17633.1 - 0.15 12.4 1.4 0.46 10.8 0.8 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF778) adh_short PF00106.25 KKK17634.1 - 1.1e-22 80.5 0.0 1.8e-22 79.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KKK17634.1 - 1.3e-13 51.0 0.0 2.3e-13 50.3 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KKK17634.1 - 6.6e-08 32.7 0.1 1.4e-07 31.6 0.1 1.7 1 1 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 KKK17634.1 - 0.00023 20.7 0.0 0.0004 19.9 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_7 PF13241.6 KKK17634.1 - 0.0027 18.1 0.2 0.0057 17.1 0.2 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding THF_DHG_CYH_C PF02882.19 KKK17634.1 - 0.0055 16.0 0.2 0.01 15.1 0.2 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.21 KKK17634.1 - 0.038 13.5 0.0 0.071 12.6 0.0 1.5 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KKK17634.1 - 0.045 12.9 0.0 0.073 12.2 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Shikimate_DH PF01488.20 KKK17634.1 - 0.045 13.8 0.2 0.092 12.8 0.2 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase PTS_2-RNA PF01885.16 KKK17634.1 - 0.055 13.5 0.0 0.082 13.0 0.0 1.2 1 0 0 1 1 1 0 RNA 2'-phosphotransferase, Tpt1 / KptA family 3HCDH_N PF02737.18 KKK17634.1 - 0.071 13.0 0.3 0.13 12.1 0.3 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 KKK17634.1 - 0.11 12.8 0.1 0.22 11.8 0.1 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain FA_hydroxylase PF04116.13 KKK17635.1 - 1e-17 64.7 5.8 1e-17 64.7 5.8 2.2 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily Spt5_N PF11942.8 KKK17635.1 - 1.9 9.5 7.1 3.5 8.7 7.1 1.3 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal Ribosomal_L6e PF01159.19 KKK17636.1 - 2e-38 131.3 0.3 2e-38 131.3 0.3 1.5 2 0 0 2 2 2 1 Ribosomal protein L6e AGP PF06376.12 KKK17636.1 - 0.15 11.9 0.5 0.44 10.4 0.2 1.9 2 0 0 2 2 2 0 Arabinogalactan peptide Proteasom_Rpn13 PF04683.13 KKK17637.1 - 1.6e-26 92.7 0.0 2.4e-26 92.1 0.0 1.3 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor RPN13_C PF16550.5 KKK17637.1 - 8.9e-13 48.4 1.6 1e-10 41.8 1.5 2.6 2 1 0 2 2 2 1 UCH-binding domain Ion_trans PF00520.31 KKK17638.1 - 6.7e-121 402.1 86.1 3.5e-40 137.8 8.0 5.0 4 1 0 4 4 4 4 Ion transport protein GPHH PF16905.5 KKK17638.1 - 0.00055 19.7 0.0 0.0012 18.5 0.0 1.6 1 0 0 1 1 1 1 Voltage-dependent L-type calcium channel, IQ-associated EF-hand_1 PF00036.32 KKK17638.1 - 0.0013 18.2 0.0 0.0036 16.8 0.0 1.8 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 KKK17638.1 - 0.0025 18.2 0.0 0.013 15.9 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 KKK17638.1 - 0.0045 16.8 0.0 0.02 14.8 0.0 2.1 1 0 0 1 1 1 1 EF-hand domain UQ_con PF00179.26 KKK17639.1 - 3.1e-36 124.1 0.0 4.8e-36 123.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KKK17639.1 - 0.019 14.6 0.0 0.037 13.7 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic E2 family B RNB PF00773.19 KKK17640.1 - 2.9e-83 279.9 0.0 6.4e-83 278.8 0.0 1.6 1 0 0 1 1 1 1 RNB domain OB_Dis3 PF17849.1 KKK17640.1 - 9.9e-27 92.8 0.0 3.5e-26 91.0 0.0 2.1 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) Dis3l2_C_term PF17877.1 KKK17640.1 - 3.2e-26 91.5 0.0 1.9e-25 89.0 0.0 2.3 2 0 0 2 2 2 1 DIS3-like exonuclease 2 C terminal Rrp44_CSD1 PF17216.3 KKK17640.1 - 1.5e-05 24.7 0.0 3.6e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Rrp44-like cold shock domain CSD2 PF17876.1 KKK17640.1 - 4.4e-05 23.6 0.0 0.024 14.8 0.0 2.7 2 0 0 2 2 2 2 Cold shock domain Rrp44_S1 PF17215.3 KKK17640.1 - 0.17 11.8 0.0 0.63 10.0 0.0 2.0 1 0 0 1 1 1 0 S1 domain Pkinase PF00069.25 KKK17643.1 - 0.029 13.8 0.0 0.04 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain Pkinase PF00069.25 KKK17644.1 - 2.3e-70 237.0 0.0 3.1e-70 236.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK17644.1 - 3.6e-48 164.1 0.0 5.3e-48 163.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KKK17644.1 - 5.6e-05 22.1 0.0 0.00011 21.1 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KKK17644.1 - 0.00034 20.0 0.0 0.0021 17.5 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 KKK17644.1 - 0.014 14.4 0.0 0.021 13.8 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain ABC1 PF03109.16 KKK17644.1 - 0.078 13.1 0.0 0.22 11.7 0.0 1.7 1 0 0 1 1 1 0 ABC1 family F-box-like PF12937.7 KKK17645.1 - 1.2e-08 34.7 0.1 3.4e-08 33.2 0.1 1.9 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KKK17645.1 - 0.05 14.0 0.4 0.56 10.7 0.6 2.6 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) F-box PF00646.33 KKK17645.1 - 0.1 12.5 0.4 3.7 7.5 0.2 2.7 2 0 0 2 2 2 0 F-box domain F-box_5 PF18511.1 KKK17645.1 - 0.12 11.9 0.1 0.84 9.3 0.2 2.1 2 0 0 2 2 2 0 F-box DUF4048 PF13257.6 KKK17646.1 - 1.7e-70 237.8 18.3 1.7e-70 237.8 18.3 3.7 4 0 0 4 4 4 1 Domain of unknown function (DUF4048) Bap31_Bap29_C PF18035.1 KKK17646.1 - 0.045 13.8 0.9 0.1 12.6 0.9 1.6 1 0 0 1 1 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain GrpE PF01025.19 KKK17646.1 - 0.062 13.0 0.5 0.11 12.2 0.5 1.3 1 0 0 1 1 1 0 GrpE SKA1 PF07160.12 KKK17646.1 - 3.8 7.3 6.9 25 4.6 2.0 3.0 3 0 0 3 3 3 0 Spindle and kinetochore-associated protein 1 DIOX_N PF14226.6 KKK17647.1 - 8.1e-16 58.8 0.0 1.5e-15 58.0 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KKK17647.1 - 4.1e-15 56.1 0.0 9.4e-15 54.9 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily AMP-binding PF00501.28 KKK17648.1 - 4.4e-54 183.7 0.0 5.6e-54 183.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 KKK17648.1 - 1.4e-07 31.7 0.1 2.9e-07 30.7 0.1 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KKK17648.1 - 0.004 18.1 0.0 0.026 15.5 0.0 2.3 2 1 0 2 2 2 1 AMP-binding enzyme C-terminal domain DUF3283 PF11686.8 KKK17648.1 - 0.16 11.9 0.0 0.35 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3283) PS_Dcarbxylase PF02666.15 KKK17649.1 - 1.9e-37 128.8 0.0 2.6e-37 128.3 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase PSDC PF12588.8 KKK17649.1 - 2e-35 121.8 0.1 4.1e-35 120.8 0.1 1.5 1 0 0 1 1 1 1 Phophatidylserine decarboxylase RnfC_N PF13375.6 KKK17649.1 - 0.0053 16.7 0.0 1.4 9.0 0.0 2.9 3 0 0 3 3 3 2 RnfC Barrel sandwich hybrid domain Cnd3 PF12719.7 KKK17650.1 - 3e-88 295.8 1.0 3e-87 292.5 0.2 2.6 2 1 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.6 KKK17650.1 - 5.3e-09 36.4 7.3 2.4e-05 24.6 2.0 3.9 2 1 2 4 4 4 3 HEAT repeats HEAT_EZ PF13513.6 KKK17650.1 - 4.7e-07 30.2 1.1 0.075 13.6 0.1 4.3 3 0 0 3 3 3 2 HEAT-like repeat HEAT PF02985.22 KKK17650.1 - 2.3e-05 24.2 11.5 0.062 13.6 0.0 6.8 7 1 1 8 8 8 1 HEAT repeat Adaptin_N PF01602.20 KKK17650.1 - 0.0022 16.7 0.5 0.17 10.4 0.1 2.4 2 0 0 2 2 2 2 Adaptin N terminal region Cnd1 PF12717.7 KKK17650.1 - 0.0094 16.0 0.0 0.12 12.4 0.0 2.7 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 PyrBI_leader PF08052.11 KKK17650.1 - 0.18 11.8 0.2 0.43 10.6 0.2 1.6 1 0 0 1 1 1 0 PyrBI operon leader peptide PALP PF00291.25 KKK17651.1 - 2.1e-65 221.0 0.1 2.6e-65 220.8 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Oxidored_molyb PF00174.19 KKK17652.1 - 1.5e-51 174.4 0.0 2.2e-51 173.9 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 KKK17652.1 - 1.1e-18 67.6 0.6 2.2e-18 66.6 0.6 1.5 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain NinD PF17466.2 KKK17652.1 - 0.026 14.6 0.1 0.086 12.9 0.1 1.8 1 0 0 1 1 1 0 Family of unknown function zf-CHY PF05495.12 KKK17653.1 - 2.9e-12 46.9 20.6 5.1e-12 46.1 20.6 1.4 1 0 0 1 1 1 1 CHY zinc finger RNA_POL_M_15KD PF02150.16 KKK17653.1 - 0.1 12.5 9.2 9.9 6.1 0.5 3.4 2 1 1 3 3 3 0 RNA polymerases M/15 Kd subunit Zn-ribbon_8 PF09723.10 KKK17653.1 - 1.4 9.1 16.9 1.8 8.8 9.1 2.5 1 1 1 2 2 2 0 Zinc ribbon domain C1_4 PF07975.12 KKK17653.1 - 2.3 8.5 15.8 3.2 8.0 0.5 2.9 1 1 2 3 3 3 0 TFIIH C1-like domain HypA PF01155.19 KKK17653.1 - 7.5 6.6 13.1 46 4.1 13.1 2.1 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Proteasome PF00227.26 KKK17654.1 - 1.7e-56 190.8 0.1 2.4e-56 190.3 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KKK17654.1 - 8.5e-14 50.9 0.3 3e-13 49.1 0.1 2.0 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Terminase_5 PF06056.12 KKK17654.1 - 0.025 14.5 0.1 0.053 13.4 0.1 1.5 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) DUF4707 PF15806.5 KKK17654.1 - 0.11 11.5 0.0 0.19 10.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4707) zf-RanBP PF00641.18 KKK17655.1 - 1.1e-20 72.6 9.1 7.3e-11 41.2 1.5 2.4 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others RRM_1 PF00076.22 KKK17655.1 - 7.2e-08 32.1 0.0 1.8e-07 30.9 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNase_T PF00929.24 KKK17655.1 - 2.6e-06 28.1 0.0 4e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Exonuclease zf-ribbon_3 PF13248.6 KKK17655.1 - 0.2 11.1 2.4 2.4 7.7 0.3 2.7 2 0 0 2 2 2 0 zinc-ribbon domain DZR PF12773.7 KKK17655.1 - 0.28 11.2 4.2 2.3 8.3 0.2 2.4 2 0 0 2 2 2 0 Double zinc ribbon MFS_1 PF07690.16 KKK17656.1 - 2e-54 184.9 27.5 1.6e-48 165.4 20.5 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Pkinase PF00069.25 KKK17656.1 - 6.9e-13 48.6 0.0 1.6e-12 47.3 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK17656.1 - 2.2e-06 27.2 0.1 1.6e-05 24.3 0.1 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase OATP PF03137.20 KKK17656.1 - 2.8e-06 25.9 0.4 0.006 14.9 1.1 2.5 2 0 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family MFS_3 PF05977.13 KKK17656.1 - 0.0032 15.9 2.8 0.0032 15.9 2.8 2.3 2 0 0 2 2 2 2 Transmembrane secretion effector MFS_2 PF13347.6 KKK17656.1 - 0.0087 14.7 17.8 0.015 13.9 7.4 2.6 2 1 0 2 2 2 2 MFS/sugar transport protein MFS_1_like PF12832.7 KKK17656.1 - 0.55 9.0 13.2 0.3 9.9 7.3 2.7 1 1 2 3 3 3 0 MFS_1 like family Trp_oprn_chp PF09534.10 KKK17656.1 - 7.4 6.3 20.0 0.42 10.4 4.4 3.4 3 0 0 3 3 3 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Tim17 PF02466.19 KKK17657.1 - 1.5e-40 138.0 6.2 1.5e-40 138.0 6.2 1.8 2 0 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family PQQ_2 PF13360.6 KKK17658.1 - 0.041 13.5 0.1 1 8.9 0.1 2.3 1 1 0 1 1 1 0 PQQ-like domain Ldh_2 PF02615.14 KKK17658.1 - 0.077 12.1 0.1 0.13 11.4 0.1 1.2 1 0 0 1 1 1 0 Malate/L-lactate dehydrogenase BTB PF00651.31 KKK17659.1 - 7.2e-07 29.4 1.4 1.6e-06 28.3 0.3 1.9 2 0 0 2 2 2 1 BTB/POZ domain Mito_carr PF00153.27 KKK17674.1 - 0.0002 21.2 0.1 0.00027 20.8 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial carrier protein FYVE PF01363.21 KKK17675.1 - 2.3e-15 56.5 7.2 3.3e-15 56.0 7.2 1.2 1 0 0 1 1 1 1 FYVE zinc finger zf-AN1 PF01428.16 KKK17675.1 - 0.02 15.1 10.3 0.039 14.1 10.3 1.4 1 0 0 1 1 1 0 AN1-like Zinc finger Ribosomal_S27 PF01599.19 KKK17704.1 - 2.6e-14 53.1 0.1 3.9e-14 52.5 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S27a Pkinase PF00069.25 KKK17711.1 - 1.2e-46 159.2 0.0 1.9e-46 158.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK17711.1 - 2.9e-17 62.8 0.0 4.5e-17 62.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 KKK17711.1 - 0.0027 17.3 0.2 0.0052 16.4 0.2 1.4 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 KKK17711.1 - 0.017 14.4 0.1 0.031 13.6 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KKK17711.1 - 0.031 13.6 0.0 0.052 12.9 0.0 1.3 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 KKK17711.1 - 0.071 13.0 0.1 0.57 10.1 0.1 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KKK17711.1 - 0.09 11.5 0.0 0.09 11.5 0.0 2.0 2 0 0 2 2 2 0 Fungal protein kinase PsaA_PsaB PF00223.19 KKK17711.1 - 0.19 9.9 0.0 0.28 9.3 0.0 1.1 1 0 0 1 1 1 0 Photosystem I psaA/psaB protein Ribosomal_S8e PF01201.22 KKK17712.1 - 1.7e-46 157.8 2.4 2.8e-46 157.1 2.4 1.3 1 0 0 1 1 1 1 Ribosomal protein S8e Pannexin_like PF12534.8 KKK17712.1 - 7.3 5.6 6.7 10 5.1 6.7 1.1 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 Fungal_trans PF04082.18 KKK17713.1 - 2.6e-15 56.2 0.1 5e-15 55.2 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Ribosomal_L21p PF00829.21 KKK17714.1 - 1.5e-08 34.8 0.1 3.2e-08 33.8 0.0 1.6 2 0 0 2 2 2 1 Ribosomal prokaryotic L21 protein RIB43A PF05914.12 KKK17714.1 - 0.017 13.9 0.4 0.022 13.5 0.4 1.1 1 0 0 1 1 1 0 RIB43A ORC6 PF05460.13 KKK17714.1 - 1.3 8.2 9.5 1.9 7.7 9.5 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) DUF1338 PF07063.13 KKK17715.1 - 4.9e-111 371.0 0.3 6e-111 370.7 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1338) Cyc-maltodext_C PF10438.9 KKK17715.1 - 0.1 12.7 0.1 2.9 8.1 0.0 2.7 2 1 0 2 2 2 0 Cyclo-malto-dextrinase C-terminal domain Slx4 PF09494.10 KKK17715.1 - 0.13 12.2 0.0 0.59 10.1 0.0 2.2 1 0 0 1 1 1 0 Slx4 endonuclease OB_NTP_bind PF07717.16 KKK17719.1 - 8e-22 77.4 0.0 2.6e-21 75.8 0.0 1.9 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 KKK17719.1 - 1.2e-19 70.5 0.0 1.2e-19 70.5 0.0 4.2 4 2 0 4 4 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KKK17719.1 - 2.2e-13 50.5 0.0 5.4e-13 49.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KKK17719.1 - 3.3e-08 33.5 0.1 7.7e-08 32.3 0.1 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KKK17719.1 - 1.9e-05 25.0 0.0 6.6e-05 23.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KKK17719.1 - 0.00012 21.9 0.0 0.0003 20.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KKK17719.1 - 0.00023 21.5 0.1 0.00063 20.1 0.1 1.8 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 KKK17719.1 - 0.00035 19.7 0.0 0.00075 18.6 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein SRP54 PF00448.22 KKK17719.1 - 0.0045 16.6 0.2 0.011 15.3 0.2 1.7 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain PWI PF01480.17 KKK17719.1 - 0.0087 16.4 0.0 0.026 14.8 0.0 1.8 1 0 0 1 1 1 1 PWI domain AAA_23 PF13476.6 KKK17719.1 - 0.12 12.9 0.0 0.12 12.9 0.0 3.9 1 1 2 3 3 1 0 AAA domain ABC_tran PF00005.27 KKK17719.1 - 0.26 11.8 2.2 1 9.9 0.1 2.7 1 1 1 2 2 2 0 ABC transporter Mannitol_dh PF01232.23 KKK17719.1 - 0.27 11.4 1.2 0.88 9.7 0.1 2.3 2 0 0 2 2 2 0 Mannitol dehydrogenase Rossmann domain Cyt-b5 PF00173.28 KKK17720.1 - 1.2e-21 76.6 0.1 1.3e-21 76.5 0.1 1.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain VHS PF00790.19 KKK17721.1 - 1.1e-23 83.7 0.0 2.2e-23 82.7 0.0 1.5 1 0 0 1 1 1 1 VHS domain GAT PF03127.14 KKK17721.1 - 3.1e-06 27.4 0.3 6.4e-06 26.4 0.3 1.6 1 0 0 1 1 1 1 GAT domain ENTH PF01417.20 KKK17721.1 - 0.0076 16.3 0.0 0.022 14.8 0.0 1.8 2 0 0 2 2 2 1 ENTH domain ubiquitin PF00240.23 KKK17721.1 - 0.041 13.6 0.0 0.1 12.3 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin family Pantoate_transf PF02548.15 KKK17722.1 - 3.1e-109 364.3 1.2 3.7e-109 364.1 1.2 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.6 KKK17722.1 - 1.1e-08 34.8 0.4 2.1e-08 34.0 0.4 1.6 1 1 0 1 1 1 1 Phosphoenolpyruvate phosphomutase APG12 PF04110.13 KKK17723.1 - 1.4e-30 105.5 0.0 2.7e-30 104.6 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.16 KKK17723.1 - 0.056 13.6 0.0 0.073 13.3 0.0 1.2 1 0 0 1 1 1 0 Autophagy protein Atg8 ubiquitin like Ufm1 PF03671.14 KKK17723.1 - 0.069 13.2 0.2 0.13 12.4 0.2 1.4 1 0 0 1 1 1 0 Ubiquitin fold modifier 1 protein UQ_con PF00179.26 KKK17724.1 - 3.2e-36 124.1 0.1 3.7e-36 123.9 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme LAMTOR PF15454.6 KKK17725.1 - 9.2e-20 71.0 0.2 1.5e-19 70.3 0.2 1.4 1 0 0 1 1 1 1 Late endosomal/lysosomal adaptor and MAPK and MTOR activator DUF2011 PF09428.10 KKK17726.1 - 9.2e-32 109.2 0.7 4.5e-31 106.9 0.0 2.2 2 0 0 2 2 2 1 Fungal protein of unknown function (DUF2011) VIR_N PF15912.5 KKK17726.1 - 0.68 9.5 11.5 0.28 10.8 4.9 2.1 2 0 0 2 2 2 0 Virilizer, N-terminal FAM183 PF14886.6 KKK17726.1 - 6.9 7.5 8.8 1.3 9.8 2.0 2.5 2 0 0 2 2 2 0 FAM183A and FAM183B related MFS_1 PF07690.16 KKK17727.1 - 1.7e-44 152.2 43.5 1.7e-44 152.2 43.5 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KKK17727.1 - 3.8e-18 65.6 29.8 4.3e-14 52.2 5.0 3.3 2 1 1 3 3 3 3 Sugar (and other) transporter OATP PF03137.20 KKK17727.1 - 1.5 7.0 12.5 0.023 13.0 2.4 2.5 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Flavoprotein PF02441.19 KKK17728.1 - 2.6e-14 53.3 0.0 4.1e-14 52.6 0.0 1.3 1 0 0 1 1 1 1 Flavoprotein DUF1391 PF07151.12 KKK17728.1 - 0.088 12.7 0.2 0.19 11.6 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1391) SnoaL_2 PF12680.7 KKK17728.1 - 0.16 12.6 0.1 33 5.2 0.0 2.6 1 1 0 2 2 2 0 SnoaL-like domain Ribonuc_red_sm PF00268.21 KKK17729.1 - 1.5e-121 405.1 1.2 1.8e-121 404.9 1.2 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain SRP9-21 PF05486.12 KKK17730.1 - 3.1e-32 110.8 0.5 6.1e-32 109.9 0.5 1.5 1 0 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) WD40 PF00400.32 KKK17731.1 - 1.7e-16 60.3 6.1 1.4e-06 28.9 0.3 5.9 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKK17731.1 - 1.9e-08 34.5 0.0 0.00036 20.8 0.0 3.8 3 2 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 KKK17731.1 - 0.0014 17.3 0.0 2.1 6.8 0.0 3.2 2 2 1 3 3 3 2 Cytochrome D1 heme domain Frtz PF11768.8 KKK17731.1 - 0.046 12.0 0.0 0.071 11.4 0.0 1.2 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz WDCP PF15390.6 KKK17731.1 - 0.053 11.9 0.5 0.092 11.1 0.0 1.5 2 0 0 2 2 2 0 WD repeat and coiled-coil-containing protein family DUF5122 PF17164.4 KKK17731.1 - 0.096 13.0 0.3 27 5.1 0.1 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5122) beta-propeller Mito_carr PF00153.27 KKK17732.1 - 1.4e-53 178.8 4.9 9.7e-19 67.1 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein TruB_N PF01509.18 KKK17734.1 - 1.2e-46 158.7 0.0 4.8e-46 156.8 0.0 1.9 2 0 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 KKK17734.1 - 2.3e-06 27.6 0.0 4.6e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain Coilin_N PF15862.5 KKK17734.1 - 1.9 8.3 4.8 5.1 6.9 4.8 1.7 1 0 0 1 1 1 0 Coilin N-terminus Ndc1_Nup PF09531.10 KKK17734.1 - 3.2 6.3 8.3 4.5 5.8 8.3 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup WD40 PF00400.32 KKK17735.1 - 5.1e-26 90.4 8.0 0.00025 21.8 0.1 8.2 7 1 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKK17735.1 - 3.1e-06 27.4 0.0 1.7 9.0 0.0 4.9 4 1 2 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KKK17735.1 - 0.021 13.5 0.5 13 4.2 0.1 3.3 2 1 1 3 3 3 0 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KKK17735.1 - 0.23 10.4 0.0 9.6 5.1 0.0 3.1 4 0 0 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein OHCU_decarbox PF09349.10 KKK17736.1 - 3.4e-50 170.5 0.0 3.9e-50 170.4 0.0 1.0 1 0 0 1 1 1 1 OHCU decarboxylase DNMT1-RFD PF12047.8 KKK17737.1 - 0.0062 16.6 0.0 0.017 15.2 0.0 1.7 1 0 0 1 1 1 1 Cytosine specific DNA methyltransferase replication foci domain E3_UbLigase_EDD PF11547.8 KKK17737.1 - 0.041 13.6 0.6 1.5 8.6 0.9 2.9 3 0 0 3 3 3 0 E3 ubiquitin ligase EDD Ebp2 PF05890.12 KKK17738.1 - 1.9e-97 326.0 12.9 1.9e-97 326.0 12.9 2.0 2 0 0 2 2 2 1 Eukaryotic rRNA processing protein EBP2 BSP_II PF05432.11 KKK17738.1 - 0.0024 17.6 22.4 0.0024 17.6 22.4 2.0 2 0 0 2 2 2 1 Bone sialoprotein II (BSP-II) Cwf_Cwc_15 PF04889.12 KKK17738.1 - 3.4 7.3 39.1 0.45 10.2 27.9 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein SdpI PF13630.6 KKK17739.1 - 0.047 13.8 0.2 0.047 13.8 0.2 2.8 2 1 1 3 3 3 0 SdpI/YhfL protein family SapB_2 PF03489.17 KKK17739.1 - 0.11 12.6 0.2 17 5.6 0.0 2.6 2 0 0 2 2 2 0 Saposin-like type B, region 2 AMP-binding PF00501.28 KKK17740.1 - 1.3e-64 218.3 0.0 1.8e-64 217.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KKK17740.1 - 1.4e-15 58.1 0.0 3.6e-15 56.7 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain MeMO_Hyd_G PF02964.16 KKK17741.1 - 0.0032 17.5 0.1 0.005 16.9 0.1 1.2 1 0 0 1 1 1 1 Methane monooxygenase, hydrolase gamma chain adh_short PF00106.25 KKK17742.1 - 1.6e-14 53.8 0.1 1.6e-14 53.8 0.1 1.9 2 1 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KKK17742.1 - 1.3e-11 44.5 0.2 4.3e-11 42.8 0.2 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase LDB19 PF13002.7 KKK17743.1 - 6.6e-59 198.9 0.0 1.1e-58 198.2 0.0 1.3 1 0 0 1 1 1 1 Arrestin_N terminal like Arrestin_N PF00339.29 KKK17743.1 - 1e-08 35.4 0.0 2.5e-08 34.1 0.0 1.7 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain SASRP1 PF15160.6 KKK17743.1 - 3.3 7.3 11.2 0.51 10.0 5.4 2.0 2 0 0 2 2 2 0 Spermatogenesis-associated serine-rich protein 1 DIOX_N PF14226.6 KKK17744.1 - 1.9e-27 96.3 0.0 3e-27 95.7 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KKK17744.1 - 1.6e-15 57.5 0.0 3.1e-15 56.5 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Prominin PF05478.11 KKK17744.1 - 0.18 9.7 0.0 0.26 9.2 0.0 1.1 1 0 0 1 1 1 0 Prominin Amidohydro_2 PF04909.14 KKK17745.1 - 1.3e-30 107.3 0.3 2.4e-30 106.3 0.3 1.5 1 1 0 1 1 1 1 Amidohydrolase TatD_DNase PF01026.21 KKK17745.1 - 0.0068 15.8 0.0 0.015 14.6 0.0 1.5 1 0 0 1 1 1 1 TatD related DNase DIOX_N PF14226.6 KKK17746.1 - 3.3e-20 73.0 0.1 5e-20 72.4 0.1 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KKK17746.1 - 9.8e-14 51.7 0.0 2.6e-12 47.1 0.0 2.4 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MKT1_C PF12246.8 KKK17747.1 - 1.9e-75 253.2 0.0 3.2e-75 252.5 0.0 1.4 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication Thioredoxin PF00085.20 KKK17747.1 - 1.1e-59 198.8 0.3 5.4e-30 103.4 0.0 3.3 3 0 0 3 3 3 2 Thioredoxin MKT1_N PF12247.8 KKK17747.1 - 6e-30 103.5 0.0 1.6e-29 102.1 0.0 1.8 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication ERp29 PF07749.12 KKK17747.1 - 3.1e-21 76.1 2.3 4e-21 75.7 0.9 2.0 2 0 0 2 2 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_2 PF13098.6 KKK17747.1 - 1e-15 58.1 0.0 9.7e-07 29.2 0.0 3.2 2 0 0 2 2 2 2 Thioredoxin-like domain OST3_OST6 PF04756.13 KKK17747.1 - 6.1e-12 45.5 0.0 5.7e-07 29.2 0.0 2.2 1 1 1 2 2 2 2 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 KKK17747.1 - 1.9e-09 37.6 0.0 8.8e-05 22.6 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_8 PF13905.6 KKK17747.1 - 2.5e-08 34.1 0.0 0.0087 16.4 0.0 3.7 3 1 1 4 4 4 2 Thioredoxin-like XPG_I PF00867.18 KKK17747.1 - 4.6e-07 30.1 1.6 8.8e-07 29.2 0.0 2.4 3 0 0 3 3 2 1 XPG I-region AhpC-TSA PF00578.21 KKK17747.1 - 1.1e-06 28.6 0.0 0.058 13.3 0.0 2.6 2 0 0 2 2 2 2 AhpC/TSA family XPG_N PF00752.17 KKK17747.1 - 2.5e-05 24.7 0.0 7e-05 23.2 0.0 1.8 1 0 0 1 1 1 1 XPG N-terminal domain TraF PF13728.6 KKK17747.1 - 8.9e-05 22.4 0.0 0.11 12.3 0.0 2.5 2 0 0 2 2 2 2 F plasmid transfer operon protein Redoxin PF08534.10 KKK17747.1 - 9.7e-05 22.1 0.2 0.3 10.8 0.0 2.7 2 0 0 2 2 2 2 Redoxin HyaE PF07449.11 KKK17747.1 - 0.00059 19.8 0.0 0.17 11.8 0.0 2.7 2 0 0 2 2 2 1 Hydrogenase-1 expression protein HyaE Thioredoxin_9 PF14595.6 KKK17747.1 - 0.023 14.5 0.0 6.5 6.5 0.0 2.4 2 0 0 2 2 2 0 Thioredoxin DSBA PF01323.20 KKK17747.1 - 0.73 9.6 2.7 26 4.5 0.1 3.6 3 1 1 4 4 4 0 DSBA-like thioredoxin domain HSBP1 PF06825.12 KKK17748.1 - 5.2e-17 61.4 0.2 7.6e-17 60.9 0.2 1.2 1 0 0 1 1 1 1 Heat shock factor binding protein 1 Matrilin_ccoil PF10393.9 KKK17748.1 - 0.00049 19.9 0.9 0.0045 16.8 0.9 2.0 1 1 0 1 1 1 1 Trimeric coiled-coil oligomerisation domain of matrilin Apolipoprotein PF01442.18 KKK17748.1 - 0.0027 17.6 0.1 0.0031 17.4 0.1 1.1 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF2937 PF11157.8 KKK17748.1 - 0.0074 16.0 0.1 0.0079 15.9 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2937) NPV_P10 PF05531.12 KKK17748.1 - 0.012 16.0 0.1 0.016 15.7 0.1 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Baculo_PEP_C PF04513.12 KKK17748.1 - 0.013 15.6 0.1 0.015 15.4 0.1 1.1 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus CLZ PF16526.5 KKK17748.1 - 0.022 15.1 0.1 0.029 14.7 0.1 1.2 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF1932 PF09130.11 KKK17748.1 - 0.04 13.9 0.0 0.072 13.1 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF1932) Pex19 PF04614.12 KKK17748.1 - 0.072 12.9 0.5 0.083 12.6 0.5 1.0 1 0 0 1 1 1 0 Pex19 protein family BMFP PF04380.13 KKK17748.1 - 0.084 13.4 0.6 0.75 10.3 0.6 2.0 1 1 0 1 1 1 0 Membrane fusogenic activity CCDC154 PF15450.6 KKK17748.1 - 0.1 11.1 0.1 0.12 10.9 0.1 1.0 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 154 SPX PF03105.19 KKK17748.1 - 0.11 12.4 0.0 0.12 12.3 0.0 1.0 1 0 0 1 1 1 0 SPX domain Fzo_mitofusin PF04799.13 KKK17748.1 - 0.11 12.0 0.0 0.12 12.0 0.0 1.1 1 0 0 1 1 1 0 fzo-like conserved region FdhE PF04216.12 KKK17748.1 - 0.11 12.3 0.1 0.11 12.3 0.1 1.0 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation Tup_N PF08581.10 KKK17748.1 - 0.14 12.4 0.2 0.26 11.6 0.2 1.5 1 1 0 1 1 1 0 Tup N-terminal DUF1308 PF07000.11 KKK17749.1 - 4.1e-13 49.6 0.1 2.3e-11 43.9 0.1 2.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1308) DUF5614 PF18474.1 KKK17749.1 - 0.044 13.1 0.1 2.3 7.5 0.0 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5614) Cwf_Cwc_15 PF04889.12 KKK17749.1 - 4.1 7.1 15.7 4.3 7.0 12.7 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Lung_7-TM_R PF06814.13 KKK17750.1 - 9.4e-71 238.5 15.0 1.1e-70 238.2 15.0 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor DUF4112 PF13430.6 KKK17751.1 - 5.1e-34 116.7 0.6 6.6e-34 116.3 0.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) AgrD PF05931.11 KKK17751.1 - 0.66 10.0 3.4 1.1 9.4 0.7 2.2 2 0 0 2 2 2 0 Staphylococcal AgrD protein DCP2 PF05026.13 KKK17752.1 - 3.3e-30 104.2 1.1 5.7e-30 103.5 1.1 1.4 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.28 KKK17752.1 - 8.3e-18 64.7 0.0 1.7e-17 63.7 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain CTU2 PF10288.9 KKK17754.1 - 7.7e-10 39.0 1.5 4.7e-09 36.5 0.1 2.2 1 1 1 2 2 2 1 Cytoplasmic tRNA 2-thiolation protein 2 FYVE PF01363.21 KKK17754.1 - 0.14 12.3 6.0 0.21 11.7 0.8 2.3 2 0 0 2 2 2 0 FYVE zinc finger DnaJ PF00226.31 KKK17755.1 - 8.5e-20 70.6 0.6 2.3e-19 69.3 0.6 1.8 1 0 0 1 1 1 1 DnaJ domain RRM_1 PF00076.22 KKK17755.1 - 0.025 14.4 0.1 0.083 12.7 0.1 1.9 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Homez PF11569.8 KKK17756.1 - 0.079 12.4 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez NACHT_N PF17100.5 KKK17756.1 - 1.2 8.9 7.3 0.62 9.9 3.0 2.6 4 0 0 4 4 4 0 N-terminal domain of NWD NACHT-NTPase R3H-assoc PF13902.6 KKK17756.1 - 2.2 8.7 5.7 1.9 8.9 1.2 2.6 2 1 0 2 2 2 0 R3H-associated N-terminal domain GCV_T PF01571.21 KKK17757.1 - 1.7e-05 24.3 0.0 2.6e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain V_ATPase_I PF01496.19 KKK17790.1 - 0 1076.7 0.0 0 1076.5 0.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family CheZ PF04344.13 KKK17790.1 - 0.0022 18.0 1.0 0.039 13.9 0.1 2.4 2 0 0 2 2 2 1 Chemotaxis phosphatase, CheZ DUF1515 PF07439.11 KKK17790.1 - 0.0066 16.5 0.1 0.018 15.1 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1515) Filament PF00038.21 KKK17790.1 - 0.0074 15.9 5.0 0.37 10.3 1.0 2.3 2 0 0 2 2 2 2 Intermediate filament protein CdvA PF18822.1 KKK17790.1 - 0.054 13.3 3.6 10 5.9 0.6 3.2 2 1 0 2 2 2 0 CdvA-like coiled-coil domain DUF1664 PF07889.12 KKK17790.1 - 0.083 12.9 1.1 9.6 6.3 0.1 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Serine_rich PF08824.10 KKK17790.1 - 0.089 12.8 2.0 0.39 10.7 0.3 2.2 2 0 0 2 2 2 0 Serine rich protein interaction domain DUF3552 PF12072.8 KKK17790.1 - 0.089 12.2 2.0 5 6.5 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) DUF4988 PF16378.5 KKK17790.1 - 0.13 11.9 0.2 0.29 10.8 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function Fmp27_WPPW PF10359.9 KKK17790.1 - 0.16 10.8 4.1 0.32 9.8 1.6 2.0 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain ZapB PF06005.12 KKK17790.1 - 0.17 12.4 1.5 2 8.9 0.1 2.5 2 0 0 2 2 2 0 Cell division protein ZapB DASH_Dam1 PF08653.10 KKK17790.1 - 0.27 11.0 1.9 22 5.0 0.0 3.9 4 0 0 4 4 4 0 DASH complex subunit Dam1 Nup54 PF13874.6 KKK17790.1 - 0.33 11.1 1.7 2.2 8.4 0.2 2.3 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 Prefoldin_2 PF01920.20 KKK17790.1 - 0.48 10.4 3.7 0.93 9.5 0.3 2.7 3 0 0 3 3 3 0 Prefoldin subunit CorA PF01544.18 KKK17790.1 - 0.82 8.9 4.2 5.5 6.2 0.6 2.6 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein HMMR_N PF15905.5 KKK17790.1 - 0.88 9.0 2.9 4.2 6.8 0.4 2.2 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal Tektin PF03148.14 KKK17790.1 - 0.97 8.1 7.8 1.1 7.9 1.8 2.4 2 1 0 2 2 2 0 Tektin family DivIC PF04977.15 KKK17790.1 - 1.2 9.0 4.9 0.59 9.9 0.4 2.7 2 0 0 2 2 2 0 Septum formation initiator ECH_1 PF00378.20 KKK17791.1 - 1.3e-49 168.8 0.0 1.5e-49 168.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KKK17791.1 - 3.2e-20 72.9 0.0 1.3e-14 54.5 0.0 2.5 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Condensation PF00668.20 KKK17792.1 - 2.4e-77 260.6 0.0 5.2e-38 130.9 0.0 2.7 2 0 0 2 2 2 2 Condensation domain AMP-binding PF00501.28 KKK17792.1 - 2e-70 237.5 0.0 1.5e-65 221.4 0.0 2.5 2 0 0 2 2 2 2 AMP-binding enzyme PP-binding PF00550.25 KKK17792.1 - 3.6e-28 97.7 0.1 1.4e-12 47.8 0.1 3.0 2 0 0 2 2 2 2 Phosphopantetheine attachment site WES_acyltransf PF03007.16 KKK17792.1 - 0.016 15.0 0.0 0.26 11.0 0.0 2.5 2 0 0 2 2 2 0 Wax ester synthase-like Acyl-CoA acyltransferase domain AMP-binding_C PF13193.6 KKK17792.1 - 0.034 15.1 0.2 30 5.7 0.0 3.3 3 0 0 3 3 3 0 AMP-binding enzyme C-terminal domain DUF433 PF04255.14 KKK17792.1 - 0.16 11.9 0.0 18 5.3 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF433) Pro_CA PF00484.19 KKK17793.1 - 1.1e-28 100.5 0.1 2.9e-26 92.7 0.1 2.2 1 1 0 1 1 1 1 Carbonic anhydrase GGACT PF06094.12 KKK17793.1 - 0.079 13.6 0.0 0.14 12.8 0.0 1.4 1 0 0 1 1 1 0 Gamma-glutamyl cyclotransferase, AIG2-like AMP-binding PF00501.28 KKK17794.1 - 3.3e-67 226.9 0.0 5.6e-67 226.2 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 KKK17794.1 - 3.6e-58 196.8 0.0 1.9e-55 187.8 0.0 2.3 1 1 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 KKK17794.1 - 2.5e-16 59.9 0.0 8.7e-16 58.1 0.0 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Condensation PF00668.20 KKK17794.1 - 7.9e-12 44.6 0.0 4.9e-11 42.0 0.0 1.9 1 1 0 1 1 1 1 Condensation domain PP-binding PF00550.25 KKK17794.1 - 9e-09 35.6 0.0 2.1e-08 34.4 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.19 KKK17794.1 - 2.8e-07 29.8 0.0 6.7e-07 28.6 0.0 1.6 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KKK17794.1 - 2.5e-05 24.3 0.0 5.8e-05 23.1 0.0 1.7 1 1 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 KKK17794.1 - 0.00027 20.4 0.0 0.00047 19.7 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 KKK17794.1 - 0.0009 18.4 0.0 0.071 12.2 0.0 2.4 2 0 0 2 2 2 1 RmlD substrate binding domain AMP-binding_C PF13193.6 KKK17794.1 - 0.0036 18.3 0.0 0.017 16.1 0.0 2.3 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain BLM10_mid PF16507.5 KKK17795.1 - 1.5e-204 680.5 0.0 2.4e-204 679.9 0.0 1.3 1 0 0 1 1 1 1 Proteasome-substrate-size regulator, mid region Mannosyl_trans2 PF04188.13 KKK17795.1 - 1.1e-49 170.0 18.9 1.1e-49 170.0 18.9 1.8 2 0 0 2 2 2 1 Mannosyltransferase (PIG-V) DUF3437 PF11919.8 KKK17795.1 - 9.9e-29 99.1 0.0 6.3e-28 96.5 0.0 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3437) BLM10_N PF16547.5 KKK17795.1 - 1.1e-18 67.2 0.0 3.1e-18 65.8 0.0 1.8 1 0 0 1 1 1 1 Proteasome-substrate-size regulator, N-terminal CLASP_N PF12348.8 KKK17795.1 - 9.7e-07 28.6 0.1 0.017 14.7 0.0 3.1 3 0 0 3 3 3 2 CLASP N terminal HEAT PF02985.22 KKK17795.1 - 0.089 13.1 0.1 4.3 7.9 0.0 4.1 4 0 0 4 4 4 0 HEAT repeat Oxidored-like PF09791.9 KKK17797.1 - 8.5e-23 79.8 3.7 1.6e-22 78.9 3.7 1.5 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal DUF5522 PF17653.1 KKK17797.1 - 0.071 13.1 3.1 0.15 12.1 3.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5522) DUF1843 PF08898.10 KKK17798.1 - 0.26 11.8 0.6 0.53 10.8 0.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1843) DUF3439 PF11921.8 KKK17798.1 - 3.2 7.7 5.8 11 6.0 5.8 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Ribosomal_L13e PF01294.18 KKK17799.1 - 1.4e-56 191.1 1.4 4.6e-56 189.5 1.4 1.9 1 0 0 1 1 1 1 Ribosomal protein L13e GCIP PF13324.6 KKK17800.1 - 8.9e-20 71.4 4.3 1.2e-19 70.9 4.3 1.1 1 0 0 1 1 1 1 Grap2 and cyclin-D-interacting RXT2_N PF08595.11 KKK17800.1 - 0.0062 16.6 4.3 0.0099 15.9 4.3 1.3 1 0 0 1 1 1 1 RXT2-like, N-terminal Sigma70_ner PF04546.13 KKK17800.1 - 0.007 16.3 7.0 0.007 16.3 7.0 1.7 2 0 0 2 2 2 1 Sigma-70, non-essential region VSG_B PF13206.6 KKK17800.1 - 0.0082 15.4 0.9 0.011 15.0 0.9 1.3 1 0 0 1 1 1 1 Trypanosomal VSG domain SDA1 PF05285.12 KKK17800.1 - 0.019 14.4 8.4 0.022 14.2 8.4 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 KKK17800.1 - 0.043 12.0 10.6 0.05 11.8 10.6 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 KKK17800.1 - 0.049 11.9 6.6 0.063 11.6 6.6 1.1 1 0 0 1 1 1 0 CDC45-like protein LTV PF04180.14 KKK17800.1 - 0.12 12.1 10.6 0.16 11.7 10.6 1.1 1 0 0 1 1 1 0 Low temperature viability protein RRN3 PF05327.11 KKK17800.1 - 0.22 10.0 6.8 0.28 9.7 6.8 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 RNA_pol_3_Rpc31 PF11705.8 KKK17800.1 - 0.22 11.8 14.5 0.3 11.3 14.5 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 TRAP_alpha PF03896.16 KKK17800.1 - 0.34 10.1 4.8 0.42 9.8 4.8 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit NOA36 PF06524.12 KKK17800.1 - 0.37 10.1 14.5 0.5 9.6 14.5 1.1 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 KKK17800.1 - 0.48 8.5 16.3 0.6 8.1 16.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi TFB6 PF17110.5 KKK17800.1 - 1.1 9.0 4.6 1.9 8.2 4.6 1.4 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH PI3K_1B_p101 PF10486.9 KKK17800.1 - 1.2 6.8 4.9 1.5 6.5 4.9 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Sporozoite_P67 PF05642.11 KKK17800.1 - 1.6 6.7 5.8 2.4 6.1 5.8 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Pox_Ag35 PF03286.14 KKK17800.1 - 3.5 7.4 8.8 25 4.6 9.0 2.0 2 0 0 2 2 2 0 Pox virus Ag35 surface protein YL1 PF05764.13 KKK17800.1 - 5.1 7.1 18.4 7.3 6.6 18.4 1.1 1 0 0 1 1 1 0 YL1 nuclear protein F-box-like PF12937.7 KKK17801.1 - 0.027 14.4 0.1 0.11 12.4 0.0 2.1 2 0 0 2 2 2 0 F-box-like Bac_surface_Ag PF01103.23 KKK17802.1 - 9.6e-39 133.7 0.1 1.5e-38 133.2 0.1 1.2 1 0 0 1 1 1 1 Surface antigen Yip1 PF04893.17 KKK17802.1 - 7e-05 22.6 18.9 0.0012 18.7 9.5 2.4 2 0 0 2 2 2 2 Yip1 domain Sporozoite_P67 PF05642.11 KKK17802.1 - 7.1 4.6 7.2 12 3.8 7.2 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen AAA PF00004.29 KKK17803.1 - 2e-43 148.0 0.0 3.4e-43 147.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KKK17803.1 - 5e-14 51.8 0.0 1e-13 50.9 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 KKK17803.1 - 6.7e-08 32.6 0.0 1.6e-07 31.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KKK17803.1 - 1.2e-07 32.0 0.0 2.4e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 KKK17803.1 - 1.3e-06 28.9 0.0 8.8e-05 23.0 0.0 2.8 2 1 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 KKK17803.1 - 2.3e-05 24.7 0.3 0.0081 16.4 0.0 2.4 1 1 1 2 2 2 1 AAA domain Prot_ATP_ID_OB PF16450.5 KKK17803.1 - 2.7e-05 24.0 2.2 6.5e-05 22.8 2.2 1.7 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain RuvB_N PF05496.12 KKK17803.1 - 0.0001 22.1 0.0 0.0002 21.1 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 KKK17803.1 - 0.00023 21.7 0.0 0.016 15.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.13 KKK17803.1 - 0.0012 18.1 0.0 0.0026 17.0 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 KKK17803.1 - 0.0015 18.7 0.0 0.0031 17.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KKK17803.1 - 0.0025 17.5 0.0 0.0046 16.7 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 KKK17803.1 - 0.0047 16.3 0.1 0.018 14.4 0.1 1.9 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 KKK17803.1 - 0.0053 16.6 0.0 0.015 15.2 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 KKK17803.1 - 0.0063 15.9 0.0 0.02 14.3 0.0 1.8 2 0 0 2 2 1 1 KaiC AAA_28 PF13521.6 KKK17803.1 - 0.011 16.0 0.0 0.019 15.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 KKK17803.1 - 0.015 15.3 0.0 0.029 14.4 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF815 PF05673.13 KKK17803.1 - 0.023 13.9 0.0 0.041 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Sigma54_activat PF00158.26 KKK17803.1 - 0.025 14.3 0.1 0.11 12.2 0.0 2.1 2 1 0 2 2 2 0 Sigma-54 interaction domain AAA_24 PF13479.6 KKK17803.1 - 0.027 14.2 0.0 0.066 12.9 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KKK17803.1 - 0.032 13.8 0.0 0.058 12.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region PhoH PF02562.16 KKK17803.1 - 0.033 13.7 0.0 0.14 11.6 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein HR1 PF02185.16 KKK17803.1 - 0.037 14.2 0.8 0.095 12.8 0.8 1.7 1 0 0 1 1 1 0 Hr1 repeat RNA_helicase PF00910.22 KKK17803.1 - 0.04 14.3 0.0 0.079 13.4 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_14 PF13173.6 KKK17803.1 - 0.046 13.8 0.0 0.079 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 KKK17803.1 - 0.052 13.9 0.0 0.62 10.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 KKK17803.1 - 0.059 12.9 0.1 0.16 11.5 0.0 1.7 2 0 0 2 2 1 0 AAA domain Parvo_NS1 PF01057.17 KKK17803.1 - 0.061 12.4 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DUF2072 PF09845.9 KKK17803.1 - 0.061 13.6 0.1 0.13 12.5 0.1 1.5 1 0 0 1 1 1 0 Zn-ribbon containing protein Zeta_toxin PF06414.12 KKK17803.1 - 0.097 11.9 0.0 0.17 11.1 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Prot_ATP_OB_N PF17758.1 KKK17803.1 - 0.11 12.2 0.3 0.42 10.3 0.1 2.1 2 0 0 2 2 1 0 Proteasomal ATPase OB N-terminal domain FGGY_C PF02782.16 KKK17804.1 - 5.2e-50 169.9 0.1 8.8e-50 169.2 0.1 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 KKK17804.1 - 1.9e-23 83.3 0.1 1.6e-22 80.3 0.1 2.1 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.20 KKK17804.1 - 0.01 15.3 0.0 0.032 13.7 0.0 1.8 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family DEDD_Tnp_IS110 PF01548.17 KKK17804.1 - 0.09 12.7 0.8 1 9.2 0.2 2.4 2 0 0 2 2 2 0 Transposase Na_Ca_ex PF01699.24 KKK17805.1 - 2.6e-20 72.9 35.4 1.6e-14 54.1 14.1 4.6 5 1 0 5 5 5 2 Sodium/calcium exchanger protein YccF PF03733.13 KKK17805.1 - 8e-15 55.3 11.1 8e-15 55.3 11.1 4.5 5 0 0 5 5 5 1 Inner membrane component domain NOA36 PF06524.12 KKK17805.1 - 0.47 9.7 17.4 0.15 11.3 13.2 1.9 2 0 0 2 2 2 0 NOA36 protein GCIP PF13324.6 KKK17805.1 - 0.96 9.0 3.2 2 7.9 3.2 1.5 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting DNA_pol_phi PF04931.13 KKK17805.1 - 3.8 5.5 14.0 5.7 4.9 14.0 1.1 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 KKK17805.1 - 6.3 4.9 11.2 8.9 4.4 11.2 1.1 1 0 0 1 1 1 0 Nop14-like family Cwf_Cwc_15 PF04889.12 KKK17805.1 - 7.3 6.2 14.2 14 5.4 14.2 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein UFD1 PF03152.14 KKK17806.1 - 1.5e-26 92.9 0.0 1.8e-16 60.1 0.0 3.3 3 0 0 3 3 3 3 Ubiquitin fusion degradation protein UFD1 AZUL PF16558.5 KKK17806.1 - 5.1e-08 33.0 0.4 1.9e-07 31.2 0.4 2.0 1 0 0 1 1 1 1 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A zinc_ribbon_4 PF13717.6 KKK17806.1 - 0.19 11.7 3.7 16 5.5 0.1 3.6 3 0 0 3 3 3 0 zinc-ribbon domain K_channel_TID PF07941.11 KKK17806.1 - 1 9.8 10.2 27 5.3 0.0 2.9 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain ABC1 PF03109.16 KKK17808.1 - 1.6e-21 76.7 0.0 6e-12 45.8 0.0 2.7 3 0 0 3 3 3 2 ABC1 family Raf1_HTH PF18579.1 KKK17808.1 - 0.0028 17.3 0.0 0.0064 16.2 0.0 1.6 1 0 0 1 1 1 1 Rubisco accumulation factor 1 helix turn helix domain RIO1 PF01163.22 KKK17808.1 - 0.018 14.6 0.0 0.33 10.5 0.0 2.2 2 0 0 2 2 2 0 RIO1 family Cyto_heme_lyase PF01265.17 KKK17809.1 - 7.1e-131 436.1 1.3 8e-131 435.9 1.3 1.0 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase NOG1 PF06858.14 KKK17810.1 - 0.066 13.0 0.1 0.2 11.5 0.1 1.8 1 0 0 1 1 1 0 Nucleolar GTP-binding protein 1 (NOG1) Imm50 PF15594.6 KKK17810.1 - 0.077 13.2 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 Immunity protein 50 Arm PF00514.23 KKK17810.1 - 0.11 12.5 0.1 6.2 7.0 0.0 3.6 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat ATP-grasp_2 PF08442.10 KKK17811.1 - 1.7e-76 256.3 0.4 1.7e-76 256.3 0.4 1.7 2 0 0 2 2 2 1 ATP-grasp domain Ligase_CoA PF00549.19 KKK17811.1 - 4.1e-25 88.4 0.3 4.1e-25 88.4 0.3 1.8 2 0 0 2 2 2 1 CoA-ligase ATP-grasp_5 PF13549.6 KKK17811.1 - 1e-08 34.9 0.4 3e-08 33.4 0.4 1.7 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 KKK17811.1 - 0.00013 21.8 1.4 0.0071 16.1 0.1 2.7 2 1 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Succ_CoA_lig PF13607.6 KKK17811.1 - 0.041 13.7 0.3 14 5.5 0.0 3.1 2 1 1 3 3 3 0 Succinyl-CoA ligase like flavodoxin domain VID27_N PF17748.1 KKK17811.1 - 0.14 12.0 0.6 0.27 11.1 0.6 1.4 1 0 0 1 1 1 0 VID27 N-terminal region adh_short PF00106.25 KKK17812.1 - 3.9e-34 117.8 0.1 7.2e-34 117.0 0.1 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KKK17812.1 - 1.7e-21 76.9 0.1 7.4e-21 74.8 0.1 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 KKK17812.1 - 0.00073 19.0 0.0 0.0012 18.3 0.0 1.5 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) NmrA PF05368.13 KKK17812.1 - 0.0088 15.6 0.1 0.041 13.4 0.0 2.0 3 0 0 3 3 3 1 NmrA-like family NAD_binding_10 PF13460.6 KKK17812.1 - 0.009 15.9 0.0 0.016 15.1 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 KKK17812.1 - 0.024 14.5 0.1 0.19 11.6 0.0 2.0 2 0 0 2 2 2 0 KR domain 2-Hacid_dh_C PF02826.19 KKK17812.1 - 0.091 12.1 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Epimerase PF01370.21 KKK17812.1 - 0.096 12.1 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family UQ_con PF00179.26 KKK17813.1 - 6.1e-20 71.3 0.1 8.8e-20 70.8 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme SLAC1 PF03595.17 KKK17814.1 - 6.3e-76 255.7 51.6 7.3e-76 255.5 51.6 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel COX14 PF14880.6 KKK17814.1 - 0.053 13.4 0.2 0.053 13.4 0.2 2.3 2 0 0 2 2 2 0 Cytochrome oxidase c assembly Pribosyltran PF00156.27 KKK17815.1 - 1.4e-05 24.7 0.0 2.3e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain DPM3 PF08285.11 KKK17816.1 - 1.5e-32 111.6 0.1 1.1e-29 102.5 0.0 2.0 2 0 0 2 2 2 2 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) HSF_DNA-bind PF00447.17 KKK17817.1 - 3.8e-30 104.4 0.7 6.7e-30 103.6 0.7 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding Lipase_GDSL PF00657.22 KKK17817.1 - 0.11 12.5 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase DUF3245 PF11595.8 KKK17818.1 - 6.4e-54 182.5 7.3 6.4e-54 182.5 7.3 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF3245) NOA36 PF06524.12 KKK17818.1 - 2.1 7.6 8.6 3.7 6.8 8.6 1.5 1 0 0 1 1 1 0 NOA36 protein LRR_4 PF12799.7 KKK17819.1 - 7.3e-25 86.6 40.7 8.1e-06 26.1 2.2 9.9 5 3 5 11 11 11 11 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KKK17819.1 - 1.2e-22 79.5 40.3 1.5e-07 31.1 4.4 8.1 4 3 4 8 8 8 8 Leucine rich repeat LRR_1 PF00560.33 KKK17819.1 - 8.4e-06 25.6 33.9 1.6 9.6 0.1 10.9 11 0 0 11 11 11 3 Leucine Rich Repeat LRR_6 PF13516.6 KKK17819.1 - 0.0001 22.0 25.9 6.4 7.1 0.1 10.1 11 0 0 11 11 11 4 Leucine Rich repeat LRR_9 PF14580.6 KKK17819.1 - 0.01 15.3 17.4 0.065 12.7 1.2 4.4 3 2 2 5 5 5 0 Leucine-rich repeat Pkinase PF00069.25 KKK17850.1 - 3.6e-40 138.0 0.0 6.3e-39 133.9 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK17850.1 - 4.6e-24 85.1 0.0 6.9e-24 84.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase K_oxygenase PF13434.6 KKK17851.1 - 2.6e-110 368.8 0.0 3.1e-110 368.5 0.0 1.1 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 KKK17851.1 - 2.5e-07 30.3 0.0 0.00034 20.0 0.0 2.3 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DUF3530 PF12048.8 KKK17851.1 - 0.079 12.4 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) BNR_2 PF13088.6 KKK17858.1 - 2e-07 30.6 0.0 0.0023 17.3 0.0 3.2 1 1 2 3 3 3 2 BNR repeat-like domain BNR PF02012.20 KKK17858.1 - 0.00078 19.1 15.2 0.48 10.6 0.2 5.1 5 0 0 5 5 5 3 BNR/Asp-box repeat Sortilin-Vps10 PF15902.5 KKK17858.1 - 0.09 11.5 0.1 3 6.5 0.0 2.5 2 1 0 2 2 2 0 Sortilin, neurotensin receptor 3, DUF3128 PF11326.8 KKK17859.1 - 0.15 12.5 2.6 1.1 9.7 0.4 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3128) IncF PF17626.2 KKK17863.1 - 0.012 16.0 0.3 0.052 13.9 0.3 2.2 1 0 0 1 1 1 0 Inclusion membrane protein F Mitofilin PF09731.9 KKK17863.1 - 0.11 11.3 5.8 0.14 10.9 5.8 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Macoilin PF09726.9 KKK17863.1 - 0.35 9.4 15.3 0.44 9.1 15.3 1.0 1 0 0 1 1 1 0 Macoilin family TFIIA PF03153.13 KKK17863.1 - 2.1 8.2 17.5 2.9 7.8 17.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit GREB1 PF15782.5 KKK17863.1 - 6.7 3.7 16.0 8.7 3.3 16.0 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer HAD_2 PF13419.6 KKK17864.1 - 2.4e-05 24.5 0.0 0.014 15.5 0.0 2.3 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KKK17864.1 - 0.0069 16.4 0.0 0.014 15.4 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 KKK17864.1 - 0.011 16.1 0.0 0.18 12.0 0.0 2.1 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase NAD_binding_8 PF13450.6 KKK17865.1 - 6.5e-08 32.7 0.2 8.7e-08 32.3 0.2 1.2 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 KKK17865.1 - 1.3e-05 24.6 0.2 1.5e-05 24.4 0.2 1.0 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KKK17865.1 - 4.8e-05 23.1 0.5 0.0001 22.0 0.5 1.5 1 1 1 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KKK17865.1 - 0.0011 18.3 0.2 0.0011 18.3 0.2 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KKK17865.1 - 0.0018 17.4 0.6 0.0019 17.4 0.6 1.1 1 0 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.14 KKK17865.1 - 0.0098 14.8 0.4 0.01 14.7 0.4 1.0 1 0 0 1 1 1 1 Tryptophan halogenase Thi4 PF01946.17 KKK17865.1 - 0.016 14.5 0.2 0.016 14.5 0.2 1.1 1 0 0 1 1 1 0 Thi4 family UDPG_MGDP_dh_N PF03721.14 KKK17865.1 - 0.029 13.9 0.3 0.035 13.7 0.3 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ThiF PF00899.21 KKK17865.1 - 0.043 13.2 0.0 0.052 12.9 0.0 1.1 1 0 0 1 1 1 0 ThiF family CK_II_beta PF01214.18 KKK17869.1 - 9.1e-78 260.2 0.0 2.7e-77 258.7 0.0 1.7 1 1 0 1 1 1 1 Casein kinase II regulatory subunit PknG_rubred PF16919.5 KKK17869.1 - 0.19 11.9 1.3 0.36 11.0 0.1 2.0 2 0 0 2 2 2 0 Protein kinase G rubredoxin domain Spt5_N PF11942.8 KKK17869.1 - 0.2 12.7 10.8 0.14 13.2 6.3 2.3 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal RRN3 PF05327.11 KKK17869.1 - 0.39 9.2 0.9 0.51 8.8 0.9 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CENP-B_dimeris PF09026.10 KKK17869.1 - 0.76 10.2 8.8 2.2 8.7 8.7 1.8 2 0 0 2 2 2 0 Centromere protein B dimerisation domain DUF3439 PF11921.8 KKK17869.1 - 1.4 8.9 6.1 2.3 8.2 6.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) DUF4637 PF15470.6 KKK17869.1 - 3.2 7.5 12.2 0.49 10.1 4.6 3.0 3 1 0 3 3 3 0 Domain of unknown function (DUF4637) DNA_pol_phi PF04931.13 KKK17869.1 - 7 4.6 5.4 9.6 4.2 5.4 1.1 1 0 0 1 1 1 0 DNA polymerase phi TRAM_LAG1_CLN8 PF03798.16 KKK17870.1 - 2.1e-44 151.7 23.7 2.1e-44 151.7 23.7 1.9 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.11 KKK17870.1 - 5.5e-18 64.4 0.1 1.4e-17 63.1 0.1 1.7 1 0 0 1 1 1 1 TRAM1-like protein Fungal_trans_2 PF11951.8 KKK17871.1 - 9.5e-13 47.7 1.1 2.9e-12 46.1 0.1 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Apc15p PF05841.11 KKK17871.1 - 3.9 8.3 7.2 0.16 12.8 0.8 2.0 3 0 0 3 3 3 0 Apc15p protein Rad10 PF03834.14 KKK17872.1 - 4.6e-46 155.5 0.1 6.9e-46 155.0 0.1 1.3 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH PF00633.23 KKK17872.1 - 0.00055 19.7 0.0 0.0012 18.6 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_5 PF14520.6 KKK17872.1 - 0.00058 20.4 0.0 0.0011 19.5 0.0 1.4 1 0 0 1 1 1 1 Helix-hairpin-helix domain ssDNA_DBD PF18333.1 KKK17872.1 - 0.061 13.4 0.2 0.12 12.5 0.2 1.5 1 0 0 1 1 1 0 Non-canonical single-stranded DNA-binding domain HHH_2 PF12826.7 KKK17872.1 - 0.15 12.2 0.0 0.26 11.4 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix motif RRM_1 PF00076.22 KKK17873.1 - 9.7e-65 214.3 0.1 5.4e-18 64.6 0.1 5.6 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 KKK17873.1 - 8e-07 29.5 1.5 16 5.7 0.0 7.0 4 4 3 7 7 7 1 Cytosolic domain of 10TM putative phosphate transporter RRM_7 PF16367.5 KKK17873.1 - 0.00013 22.1 0.0 3.7 7.7 0.0 4.2 3 1 0 3 3 3 2 RNA recognition motif RRM_Rrp7 PF17799.1 KKK17873.1 - 0.0026 17.6 0.2 1.2 8.9 0.0 3.5 2 2 1 3 3 3 1 Rrp7 RRM-like N-terminal domain Nup35_RRM_2 PF14605.6 KKK17873.1 - 0.0045 16.9 0.0 0.61 10.1 0.0 2.8 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif DbpA PF03880.15 KKK17873.1 - 0.023 14.7 0.1 7.6 6.6 0.0 2.6 2 0 0 2 2 2 0 DbpA RNA binding domain AA_permease PF00324.21 KKK17874.1 - 5.5e-107 358.3 38.0 9.3e-101 337.8 25.4 2.0 2 0 0 2 2 2 2 Amino acid permease AA_permease_2 PF13520.6 KKK17874.1 - 7.2e-19 67.9 25.6 7.2e-19 67.9 25.6 1.9 2 0 0 2 2 2 1 Amino acid permease DUF1772 PF08592.11 KKK17874.1 - 0.0068 16.7 1.4 0.0068 16.7 1.4 3.5 3 1 0 3 3 3 1 Domain of unknown function (DUF1772) Cupin_8 PF13621.6 KKK17875.1 - 2.4e-25 89.7 0.0 4e-25 89.0 0.0 1.3 1 1 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 KKK17875.1 - 0.0074 15.8 0.0 0.014 14.8 0.0 1.4 1 0 0 1 1 1 1 Cupin superfamily protein Cupin_2 PF07883.11 KKK17875.1 - 0.011 15.4 0.0 0.041 13.6 0.0 1.8 2 0 0 2 2 2 0 Cupin domain Fungal_trans PF04082.18 KKK17876.1 - 4.8e-18 65.1 0.0 8.4e-18 64.3 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK17876.1 - 1.7e-06 28.0 14.2 2.8e-06 27.3 14.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HalX PF08663.10 KKK17876.1 - 0.13 12.6 0.1 0.26 11.6 0.1 1.5 1 0 0 1 1 1 0 HalX domain Cyt-b5 PF00173.28 KKK17877.1 - 3.9e-08 33.3 0.0 4.4e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain CcmE PF03100.15 KKK17879.1 - 0.19 11.7 1.4 0.31 11.0 0.0 1.9 2 0 0 2 2 2 0 CcmE Cation_ATPase_C PF00689.21 KKK17879.1 - 0.54 9.9 7.4 3.1 7.5 6.6 2.0 2 0 0 2 2 2 0 Cation transporting ATPase, C-terminus FAD_binding_1 PF00667.20 KKK17882.1 - 2.9e-44 151.3 0.0 4.1e-44 150.8 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 KKK17882.1 - 4.4e-10 40.2 0.0 1.4e-09 38.6 0.0 1.9 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain Glyco_hydro_31 PF01055.26 KKK17883.1 - 5.1e-140 467.5 1.8 7.4e-140 467.0 1.8 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 KKK17883.1 - 1e-22 80.5 0.4 2.4e-16 59.9 0.3 2.5 1 1 1 2 2 2 2 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Rotavirus_VP7 PF05868.11 KKK17883.1 - 0.0018 17.7 0.2 0.0032 16.9 0.2 1.3 1 0 0 1 1 1 1 Rotavirus major outer capsid protein VP7 Gal_mutarotas_2 PF13802.6 KKK17883.1 - 0.073 13.4 0.6 0.37 11.2 0.2 2.4 2 0 0 2 2 2 0 Galactose mutarotase-like HNH_2 PF13391.6 KKK17884.1 - 5.4e-06 26.4 0.0 1.3e-05 25.2 0.0 1.7 1 0 0 1 1 1 1 HNH endonuclease XRCC4 PF06632.12 KKK17884.1 - 0.11 11.3 7.9 0.19 10.6 7.9 1.3 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 Fringe PF02434.16 KKK17885.1 - 3.2e-09 36.6 0.0 1.2e-08 34.7 0.0 1.8 1 1 0 1 1 1 1 Fringe-like DUF604 PF04646.12 KKK17885.1 - 2.8e-07 30.2 0.0 4.8e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF604 Homez PF11569.8 KKK17885.1 - 0.14 11.7 0.0 2 7.9 0.0 2.4 2 0 0 2 2 2 0 Homeodomain leucine-zipper encoding, Homez Fungal_trans PF04082.18 KKK17886.1 - 1.6e-11 43.7 0.3 3.7e-11 42.6 0.3 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK17886.1 - 6e-09 35.9 11.6 1.5e-08 34.6 11.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SRP72 PF08492.12 KKK17887.1 - 7.3e-18 64.7 3.3 7.3e-18 64.7 3.3 2.4 2 0 0 2 2 2 1 SRP72 RNA-binding domain SRP_TPR_like PF17004.5 KKK17888.1 - 2.5e-11 43.6 0.3 7.8e-10 38.8 0.1 3.1 2 1 0 2 2 2 1 Putative TPR-like repeat TPR_14 PF13428.6 KKK17888.1 - 4.2e-09 36.5 6.7 0.03 15.1 0.1 7.2 5 2 3 8 8 8 2 Tetratricopeptide repeat TPR_19 PF14559.6 KKK17888.1 - 5.4e-07 30.0 9.6 0.0036 17.8 0.1 5.8 3 3 3 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.17 KKK17888.1 - 0.00012 21.9 3.6 15 6.0 0.0 5.9 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_4 PF07721.14 KKK17888.1 - 0.00031 21.1 0.0 9.9 7.1 0.0 4.9 5 0 0 5 5 4 1 Tetratricopeptide repeat BTAD PF03704.17 KKK17888.1 - 0.00065 20.2 4.5 0.029 14.8 0.4 3.7 3 1 0 3 3 3 1 Bacterial transcriptional activator domain TPR_12 PF13424.6 KKK17888.1 - 0.00086 19.5 1.8 3.9 7.8 0.0 5.0 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 KKK17888.1 - 0.0019 18.0 0.5 18 5.4 0.0 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 KKK17888.1 - 0.0035 17.4 3.3 1.8 9.0 0.0 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_20 PF14561.6 KKK17888.1 - 0.017 15.5 1.5 0.14 12.5 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF4810 PF16068.5 KKK17888.1 - 0.027 15.0 0.6 0.27 11.8 0.0 3.0 4 0 0 4 4 4 0 Domain of unknown function (DUF4810) PPR PF01535.20 KKK17888.1 - 0.029 14.6 2.4 34 5.0 0.0 4.9 6 0 0 6 6 5 0 PPR repeat YfdX PF10938.8 KKK17888.1 - 0.046 13.6 0.7 1.3 8.9 0.1 3.0 3 1 0 3 3 3 0 YfdX protein SPO22 PF08631.10 KKK17888.1 - 0.06 12.8 1.4 0.19 11.1 1.4 1.9 1 1 0 1 1 1 0 Meiosis protein SPO22/ZIP4 like ANAPC3 PF12895.7 KKK17888.1 - 0.076 13.2 10.5 6.2 7.1 0.1 5.1 5 1 0 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 KKK17888.1 - 0.086 13.0 2.1 0.64 10.2 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat vWA-TerF-like PF10138.9 KKK17889.1 - 8.1e-06 26.1 0.0 1.2e-05 25.5 0.0 1.2 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA PF00092.28 KKK17889.1 - 0.17 12.2 0.0 1.1 9.5 0.0 2.0 1 1 0 1 1 1 0 von Willebrand factor type A domain GFO_IDH_MocA PF01408.22 KKK17890.1 - 6.8e-11 43.0 0.0 1.5e-10 41.9 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Ribosomal_L3 PF00297.22 KKK17938.1 - 8.5e-180 597.5 11.6 1.1e-179 597.2 11.6 1.1 1 0 0 1 1 1 1 Ribosomal protein L3 TPR_1 PF00515.28 KKK17938.1 - 1.9e-50 166.7 21.8 8.5e-08 31.7 0.1 10.8 11 1 0 11 11 11 9 Tetratricopeptide repeat TPR_2 PF07719.17 KKK17938.1 - 9.1e-44 144.1 16.6 2e-05 24.3 0.0 10.7 11 0 0 11 11 10 9 Tetratricopeptide repeat TPR_8 PF13181.6 KKK17938.1 - 1.7e-36 121.3 15.4 3.3e-06 26.9 0.0 10.8 10 1 0 10 10 10 9 Tetratricopeptide repeat TPR_11 PF13414.6 KKK17938.1 - 2.6e-24 84.6 19.4 2.6e-05 23.8 1.0 9.6 6 2 3 9 9 9 7 TPR repeat TPR_17 PF13431.6 KKK17938.1 - 5.1e-24 82.9 13.5 0.003 17.8 0.1 9.6 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_14 PF13428.6 KKK17938.1 - 5.3e-23 79.7 15.5 9.4e-05 22.9 0.0 9.2 4 3 5 9 9 9 7 Tetratricopeptide repeat TPR_19 PF14559.6 KKK17938.1 - 1.3e-21 76.8 12.7 0.0016 18.9 0.0 7.0 4 2 3 7 7 7 6 Tetratricopeptide repeat TPR_16 PF13432.6 KKK17938.1 - 8.4e-21 74.4 14.4 0.00019 22.0 0.0 7.7 5 2 1 7 7 7 5 Tetratricopeptide repeat TPR_12 PF13424.6 KKK17938.1 - 3e-20 72.3 19.6 0.00021 21.5 0.7 7.7 3 2 3 7 7 7 4 Tetratricopeptide repeat TPR_7 PF13176.6 KKK17938.1 - 2.9e-18 64.5 10.9 0.045 13.8 0.1 9.5 9 1 0 9 9 9 4 Tetratricopeptide repeat TPR_6 PF13174.6 KKK17938.1 - 5e-17 61.3 15.4 0.014 16.0 0.0 9.6 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_9 PF13371.6 KKK17938.1 - 1.7e-14 53.7 10.0 0.0047 17.1 0.0 6.9 1 1 6 8 8 8 5 Tetratricopeptide repeat ANAPC3 PF12895.7 KKK17938.1 - 7.6e-13 48.5 7.1 1.2e-07 31.9 2.8 3.7 3 0 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 KKK17938.1 - 3.8e-06 26.3 14.8 0.037 13.2 0.2 5.5 2 1 4 6 6 6 3 Tetratricopeptide repeat TPR_21 PF09976.9 KKK17938.1 - 1.8e-05 24.5 3.1 0.31 10.7 0.0 4.4 2 2 2 4 4 4 2 Tetratricopeptide repeat-like domain BTAD PF03704.17 KKK17938.1 - 0.00016 22.1 7.2 0.082 13.3 0.1 3.6 3 0 0 3 3 3 2 Bacterial transcriptional activator domain TPR_MalT PF17874.1 KKK17938.1 - 0.01 15.2 8.4 0.14 11.5 0.0 3.5 2 2 1 3 3 3 0 MalT-like TPR region TPR_10 PF13374.6 KKK17938.1 - 0.076 12.9 10.8 44 4.1 0.2 6.3 7 0 0 7 7 5 0 Tetratricopeptide repeat TPR_20 PF14561.6 KKK17938.1 - 0.11 12.8 0.3 3.5 8.0 0.0 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat DUF2225 PF09986.9 KKK17938.1 - 0.13 12.0 4.5 1.8 8.2 0.0 3.1 3 1 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2225) FAP PF07174.11 KKK17939.1 - 5.8 6.3 10.3 3 7.2 4.4 2.1 2 0 0 2 2 2 0 Fibronectin-attachment protein (FAP) NuiA PF07924.11 KKK17940.1 - 0.033 14.6 0.3 0.57 10.6 0.3 2.3 1 1 0 1 1 1 0 Nuclease A inhibitor-like protein Methyltr_RsmB-F PF01189.17 KKK17958.1 - 1e-61 208.1 0.4 4e-61 206.2 0.0 2.2 2 1 0 2 2 2 1 16S rRNA methyltransferase RsmB/F Methyltr_RsmF_N PF17125.5 KKK17958.1 - 1.6e-07 31.7 0.0 4.3e-07 30.4 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of 16S rRNA methyltransferase RsmF FtsJ PF01728.19 KKK17958.1 - 0.0051 16.9 0.0 0.011 15.9 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase DDE_Tnp_1_6 PF13751.6 KKK17958.1 - 1.7 8.9 5.6 5 7.4 5.6 1.8 1 0 0 1 1 1 0 Transposase DDE domain MORN PF02493.20 KKK17959.1 - 2.5e-13 49.1 25.2 3.5e-05 23.4 0.4 4.6 4 0 0 4 4 4 4 MORN repeat zf-C3HC4_3 PF13920.6 KKK17959.1 - 8.7e-11 41.5 10.3 1.4e-10 40.8 10.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) UCH PF00443.29 KKK17959.1 - 3.8e-10 39.7 0.0 1.1e-09 38.2 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase USP7_ICP0_bdg PF12436.8 KKK17959.1 - 0.00012 21.5 0.0 0.00026 20.4 0.0 1.5 1 0 0 1 1 1 1 ICP0-binding domain of Ubiquitin-specific protease 7 Prok-RING_4 PF14447.6 KKK17959.1 - 0.012 15.4 10.6 0.025 14.4 10.6 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Borrelia_P83 PF05262.11 KKK17959.1 - 0.025 13.1 1.8 0.038 12.5 1.8 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein zf-RING_2 PF13639.6 KKK17959.1 - 0.18 12.2 11.1 0.38 11.1 11.1 1.6 1 0 0 1 1 1 0 Ring finger domain zf-RING_5 PF14634.6 KKK17959.1 - 0.24 11.4 11.3 0.45 10.5 11.3 1.5 1 0 0 1 1 1 0 zinc-RING finger domain RPA43_OB PF17875.1 KKK17959.1 - 8.4 7.0 8.1 39 4.9 8.1 2.1 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I DS PF01916.17 KKK17960.1 - 4.4e-130 433.1 0.1 5e-130 432.9 0.1 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase DUF2483 PF10656.9 KKK17960.1 - 0.085 13.1 0.1 3.1 8.0 0.0 2.9 3 0 0 3 3 3 0 Hypothetical protein of unknown function (DUF2483) CDT1_C PF16679.5 KKK17968.1 - 9.8e-21 74.0 0.0 2e-20 73.0 0.0 1.5 1 0 0 1 1 1 1 DNA replication factor Cdt1 C-terminal domain Lentiviral_Tat PF02998.14 KKK17968.1 - 0.016 15.2 0.2 0.098 12.7 0.1 2.2 2 0 0 2 2 2 0 Lentiviral Tat protein MutS_V PF00488.21 KKK17969.1 - 9.4e-81 270.3 0.1 1.6e-80 269.6 0.1 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KKK17969.1 - 2.2e-39 135.7 1.5 5.5e-39 134.4 1.5 1.7 1 0 0 1 1 1 1 MutS domain III MutS_II PF05188.17 KKK17969.1 - 4e-20 72.5 0.4 3.5e-19 69.4 0.0 2.7 3 0 0 3 3 3 1 MutS domain II MutS_IV PF05190.18 KKK17969.1 - 2.2e-17 63.2 0.9 7e-17 61.6 0.9 2.0 1 0 0 1 1 1 1 MutS family domain IV MutS_I PF01624.20 KKK17969.1 - 1.4e-14 54.3 0.0 1e-13 51.5 0.0 2.2 2 0 0 2 2 2 1 MutS domain I SUR7 PF06687.12 KKK17969.1 - 0.11 12.1 0.0 0.35 10.5 0.1 1.8 2 0 0 2 2 2 0 SUR7/PalI family Gpi1 PF05024.15 KKK17970.1 - 4.1e-77 258.5 8.7 4.1e-77 258.5 8.7 1.8 2 0 0 2 2 2 1 N-acetylglucosaminyl transferase component (Gpi1) Proteasome PF00227.26 KKK17975.1 - 6e-57 192.2 0.0 3e-32 111.7 0.0 2.2 1 1 1 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.9 KKK17975.1 - 9.3e-11 41.2 0.1 3.1e-10 39.5 0.0 1.9 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Amidohydro_2 PF04909.14 KKK17976.1 - 1.6e-39 136.5 0.9 1.9e-39 136.2 0.9 1.1 1 0 0 1 1 1 1 Amidohydrolase RINGv PF12906.7 KKK17977.1 - 2.5e-09 37.1 3.6 7.1e-09 35.7 0.8 2.4 2 0 0 2 2 2 1 RING-variant domain PHD_4 PF16866.5 KKK17977.1 - 0.3 11.2 1.3 2.2 8.4 1.1 2.1 2 0 0 2 2 2 0 PHD-finger zf-RING_2 PF13639.6 KKK17977.1 - 1.4 9.3 4.2 4.2 7.8 1.2 2.3 2 0 0 2 2 2 0 Ring finger domain RRM_1 PF00076.22 KKK17978.1 - 7.9e-20 70.5 0.2 1.9e-13 50.0 0.0 3.4 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KKK17978.1 - 0.048 13.8 0.0 0.59 10.3 0.0 2.3 2 0 0 2 2 2 0 RNA recognition motif Limkain-b1 PF11608.8 KKK17978.1 - 0.064 13.3 0.0 5.3 7.2 0.0 2.9 4 0 0 4 4 4 0 Limkain b1 Sugar_tr PF00083.24 KKK17979.1 - 3.2e-84 283.4 28.7 3.9e-84 283.1 28.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKK17979.1 - 6e-11 41.9 44.6 1.4e-09 37.3 16.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3824 PF12868.7 KKK17993.1 - 5.9e-32 111.4 39.3 5.9e-32 111.4 39.3 8.0 5 1 4 9 9 9 4 Domain of unknwon function (DUF3824) YdjM PF04307.14 KKK17993.1 - 0.082 12.2 0.4 1.2 8.4 0.0 2.4 2 0 0 2 2 2 0 LexA-binding, inner membrane-associated putative hydrolase UCR_TM PF02921.14 KKK17993.1 - 0.84 10.2 14.2 6.7 7.3 0.1 5.2 4 1 0 4 4 4 0 Ubiquinol cytochrome reductase transmembrane region Vac7 PF12751.7 KKK17994.1 - 2.5e-162 540.7 0.1 2.5e-162 540.7 0.1 2.5 2 1 0 2 2 2 1 Vacuolar segregation subunit 7 Pkinase PF00069.25 KKK18005.1 - 1.2e-21 77.2 0.0 6.4e-11 42.1 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KKK18005.1 - 3e-08 33.3 0.0 0.0067 15.7 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 KKK18005.1 - 0.0079 16.1 0.1 0.024 14.6 0.1 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Ras PF00071.22 KKK18006.1 - 6.5e-57 191.6 0.0 7.8e-57 191.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KKK18006.1 - 2e-34 118.4 0.0 2.8e-34 117.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKK18006.1 - 1.3e-14 54.1 0.0 2.2e-14 53.3 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KKK18006.1 - 4.6e-05 22.9 0.0 5.5e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KKK18006.1 - 5.2e-05 22.9 0.0 8.1e-05 22.2 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KKK18006.1 - 8.7e-05 22.6 0.0 0.00014 21.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KKK18006.1 - 0.00094 19.6 0.0 0.0013 19.1 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 KKK18006.1 - 0.11 12.3 0.0 1.9 8.3 0.0 2.3 3 0 0 3 3 3 0 RsgA GTPase CorA PF01544.18 KKK18009.1 - 2.8e-10 40.0 0.1 5.7e-10 39.0 0.1 1.5 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Metallophos PF00149.28 KKK18010.1 - 1.3e-12 48.6 0.0 2.3e-12 47.8 0.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KKK18010.1 - 6.3e-06 26.5 0.5 1.9e-05 24.9 0.5 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.6 KKK18010.1 - 0.065 12.6 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Metallophosphoesterase, calcineurin superfamily DUF2509 PF10713.9 KKK18010.1 - 0.14 12.2 0.0 0.31 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2509) LCCL PF03815.19 KKK18011.1 - 3.8e-22 78.2 0.0 6.3e-22 77.5 0.0 1.3 1 0 0 1 1 1 1 LCCL domain Gly_transf_sug PF04488.15 KKK18012.1 - 4e-13 49.8 0.0 1.2e-12 48.3 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif CUB PF00431.20 KKK18012.1 - 0.047 14.0 0.0 0.081 13.3 0.0 1.3 1 0 0 1 1 1 0 CUB domain ThiF PF00899.21 KKK18013.1 - 1.8e-40 138.9 0.0 2.9e-40 138.2 0.0 1.2 1 0 0 1 1 1 1 ThiF family TrkA_N PF02254.18 KKK18013.1 - 0.01 16.1 0.1 0.027 14.7 0.1 1.7 1 0 0 1 1 1 0 TrkA-N domain Sacchrp_dh_NADP PF03435.18 KKK18013.1 - 0.019 15.2 0.4 0.37 11.1 0.2 2.5 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain UDPG_MGDP_dh_N PF03721.14 KKK18013.1 - 0.11 12.1 0.1 0.25 10.9 0.1 1.6 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Melibiase_2 PF16499.5 KKK18013.1 - 0.14 11.3 0.0 0.23 10.6 0.0 1.2 1 0 0 1 1 1 0 Alpha galactosidase A LapA_dom PF06305.11 KKK18013.1 - 0.16 11.8 0.0 0.38 10.6 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain DUF4336 PF14234.6 KKK18014.1 - 1.4e-15 57.3 0.0 6.3e-11 42.0 0.0 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4336) Nse4_C PF08743.10 KKK18015.1 - 2.4e-34 117.5 0.0 6e-34 116.2 0.0 1.8 1 0 0 1 1 1 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.6 KKK18015.1 - 1.3e-16 60.4 0.0 3e-16 59.2 0.0 1.7 1 0 0 1 1 1 1 Binding domain of Nse4/EID3 to Nse3-MAGE Baculo_LEF5 PF04838.12 KKK18015.1 - 0.0059 16.7 0.1 0.87 9.6 0.0 2.5 2 1 0 2 2 2 2 Baculoviridae late expression factor 5 Cupin_8 PF13621.6 KKK18015.1 - 0.086 12.5 0.3 0.16 11.7 0.3 1.3 1 0 0 1 1 1 0 Cupin-like domain MARVEL PF01284.23 KKK18016.1 - 1e-20 74.3 14.5 1.3e-20 73.9 14.5 1.1 1 0 0 1 1 1 1 Membrane-associating domain Phage_holin_5_2 PF16079.5 KKK18016.1 - 0.93 9.9 4.8 0.36 11.2 0.6 2.4 2 1 1 3 3 3 0 Phage holin family Hol44, in holin superfamily V GMC_oxred_N PF00732.19 KKK18017.1 - 1.1e-29 103.8 0.0 2e-29 102.9 0.0 1.5 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KKK18017.1 - 1.5e-15 58.0 0.5 2.4e-15 57.3 0.5 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.24 KKK18017.1 - 3.1e-08 33.6 3.1 0.00044 19.9 0.3 2.4 2 1 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KKK18017.1 - 1.9e-06 27.3 0.1 0.016 14.3 0.0 2.4 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 KKK18017.1 - 2.5e-06 26.9 0.1 0.0023 17.2 0.0 2.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KKK18017.1 - 3e-06 27.4 0.2 2e-05 24.7 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KKK18017.1 - 1.3e-05 24.1 0.0 6.9e-05 21.7 0.0 1.9 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.27 KKK18017.1 - 0.0012 19.3 0.2 0.37 11.4 0.0 3.5 4 0 0 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KKK18017.1 - 0.002 17.4 0.0 0.023 13.9 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KKK18017.1 - 0.0034 16.7 0.0 0.0042 16.4 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 KKK18017.1 - 0.0051 16.2 0.2 0.02 14.3 0.1 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KKK18017.1 - 0.0088 15.1 0.0 0.014 14.5 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 KKK18017.1 - 0.032 13.5 0.2 0.068 12.4 0.0 1.6 2 0 0 2 2 2 0 Thi4 family NAD_binding_9 PF13454.6 KKK18017.1 - 0.054 13.5 0.0 0.14 12.1 0.0 1.7 1 0 0 1 1 1 0 FAD-NAD(P)-binding Trp_halogenase PF04820.14 KKK18017.1 - 0.086 11.7 0.1 0.12 11.1 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase MMR_HSR1 PF01926.23 KKK18018.1 - 4.8e-14 52.4 0.0 1.3e-13 51.0 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KKK18018.1 - 8.2e-07 29.1 0.1 2e-06 27.8 0.1 1.6 1 1 0 1 1 1 1 RsgA GTPase FeoB_N PF02421.18 KKK18018.1 - 1.7e-05 24.4 0.1 2.8e-05 23.7 0.1 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Septin PF00735.18 KKK18018.1 - 0.0007 19.0 0.0 0.0012 18.2 0.0 1.2 1 0 0 1 1 1 1 Septin AIG1 PF04548.16 KKK18018.1 - 0.0011 18.3 0.0 0.0018 17.6 0.0 1.3 1 0 0 1 1 1 1 AIG1 family AAA_18 PF13238.6 KKK18018.1 - 0.0034 17.9 0.1 0.0093 16.5 0.1 1.8 1 0 0 1 1 1 1 AAA domain PduV-EutP PF10662.9 KKK18018.1 - 0.0063 16.3 0.4 1.2 8.9 0.0 3.3 3 1 0 3 3 3 1 Ethanolamine utilisation - propanediol utilisation Roc PF08477.13 KKK18018.1 - 0.015 15.5 0.0 0.04 14.1 0.0 1.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase MeaB PF03308.16 KKK18018.1 - 0.024 13.6 0.0 0.04 12.9 0.0 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Dynamin_N PF00350.23 KKK18018.1 - 0.027 14.6 0.1 0.33 11.0 0.0 2.4 1 1 1 2 2 2 0 Dynamin family Arf PF00025.21 KKK18018.1 - 0.059 12.8 0.0 0.65 9.4 0.0 2.1 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA_16 PF13191.6 KKK18018.1 - 0.069 13.5 0.0 0.12 12.8 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain TniB PF05621.11 KKK18018.1 - 0.075 12.4 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein GTP_EFTU PF00009.27 KKK18018.1 - 0.077 12.5 0.1 0.5 9.9 0.0 2.3 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain SRPRB PF09439.10 KKK18018.1 - 0.1 12.0 0.0 0.23 10.9 0.0 1.6 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit NB-ARC PF00931.22 KKK18018.1 - 0.11 11.6 0.0 0.25 10.5 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain AAA_28 PF13521.6 KKK18018.1 - 0.15 12.3 0.0 0.41 10.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain PI3Ka PF00613.20 KKK18019.1 - 2.2e-59 200.0 0.1 3.6e-59 199.3 0.1 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 KKK18019.1 - 1.9e-43 149.1 0.0 1.8e-30 106.6 0.0 2.5 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.24 KKK18019.1 - 2.3e-30 105.3 0.0 3.9e-30 104.6 0.0 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 Histidinol_dh PF00815.20 KKK18021.1 - 1.4e-159 531.6 4.7 1.8e-159 531.1 4.7 1.2 1 0 0 1 1 1 1 Histidinol dehydrogenase PRA-CH PF01502.18 KKK18021.1 - 4.4e-23 80.9 0.1 1.2e-22 79.5 0.1 1.7 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.17 KKK18021.1 - 1.7e-15 57.2 0.3 5.8e-15 55.5 0.3 2.0 1 0 0 1 1 1 1 Phosphoribosyl-ATP pyrophosphohydrolase MazG PF03819.17 KKK18021.1 - 0.0094 16.1 0.2 0.023 14.9 0.2 1.6 1 0 0 1 1 1 1 MazG nucleotide pyrophosphohydrolase domain Phage_TTP_13 PF16463.5 KKK18021.1 - 0.11 12.0 0.0 2.2 7.8 0.0 2.3 2 0 0 2 2 2 0 Phage tail tube protein family Utp11 PF03998.13 KKK18022.1 - 4.3e-56 190.6 29.4 5.5e-56 190.2 29.4 1.1 1 0 0 1 1 1 1 Utp11 protein Glyco_hydro_47 PF01532.20 KKK18024.1 - 1.1e-137 459.8 0.0 1.7e-137 459.1 0.0 1.3 1 1 0 1 1 1 1 Glycosyl hydrolase family 47 Fungal_trans PF04082.18 KKK18025.1 - 4.2e-13 48.9 0.1 8.8e-13 47.9 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Ferric_reduct PF01794.19 KKK18026.1 - 3.1e-24 85.5 9.7 7.1e-24 84.3 9.7 1.6 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KKK18026.1 - 1e-12 48.1 0.0 5.4e-08 32.9 0.0 2.5 2 0 0 2 2 2 2 FAD-binding domain NAD_binding_6 PF08030.12 KKK18026.1 - 1.4e-11 44.7 0.1 1.9e-09 37.8 0.0 2.7 2 1 1 3 3 3 2 Ferric reductase NAD binding domain NAD_binding_1 PF00175.21 KKK18026.1 - 0.0037 17.9 0.0 0.078 13.6 0.0 2.5 2 1 0 2 2 2 1 Oxidoreductase NAD-binding domain ABC2_membrane PF01061.24 KKK18027.1 - 2.4e-88 295.0 59.2 7.8e-48 162.7 20.6 3.1 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.27 KKK18027.1 - 1.5e-37 129.2 0.0 4.8e-18 66.0 0.0 2.6 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 KKK18027.1 - 1.2e-35 121.3 7.7 1.1e-32 111.7 0.0 3.5 3 0 0 3 3 3 2 CDR ABC transporter ABC_trans_N PF14510.6 KKK18027.1 - 1.7e-19 70.2 0.1 4.4e-19 68.9 0.1 1.7 1 0 0 1 1 1 1 ABC-transporter N-terminal RsgA_GTPase PF03193.16 KKK18027.1 - 1.8e-06 28.0 0.1 0.00027 20.9 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_25 PF13481.6 KKK18027.1 - 3.6e-06 26.7 0.1 3.5e-05 23.5 0.0 2.4 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 KKK18027.1 - 1.6e-05 25.4 1.4 0.0022 18.4 0.1 2.8 3 0 0 3 3 2 1 AAA ATPase domain AAA_29 PF13555.6 KKK18027.1 - 0.0013 18.4 2.0 0.028 14.1 0.2 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_18 PF13238.6 KKK18027.1 - 0.0021 18.6 0.0 0.079 13.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KKK18027.1 - 0.0021 18.2 0.1 0.11 12.7 0.1 2.6 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 KKK18027.1 - 0.0024 17.7 0.0 2.9 7.6 0.1 2.8 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 KKK18027.1 - 0.0066 15.6 46.2 0.0058 15.8 18.3 2.7 2 1 0 2 2 2 1 ABC-2 family transporter protein SMC_N PF02463.19 KKK18027.1 - 0.0066 15.9 0.0 0.46 9.9 0.0 3.1 3 1 0 4 4 4 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KKK18027.1 - 0.019 15.2 2.2 1.2 9.4 0.1 3.0 3 0 0 3 3 3 0 AAA domain AAA_30 PF13604.6 KKK18027.1 - 0.03 14.1 0.0 2.4 7.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain Ploopntkinase3 PF18751.1 KKK18027.1 - 0.045 13.7 0.1 0.54 10.1 0.0 2.2 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 RNA_helicase PF00910.22 KKK18027.1 - 0.046 14.1 0.0 15 6.0 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA_17 PF13207.6 KKK18027.1 - 0.13 12.7 0.2 5.4 7.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 KKK18027.1 - 0.21 11.7 0.0 35 4.5 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase cobW PF02492.19 KKK18027.1 - 0.44 10.1 3.1 0.57 9.7 0.1 2.4 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 KKK18027.1 - 0.46 10.4 6.7 3.9 7.4 0.2 3.5 4 0 0 4 4 4 0 NACHT domain bZIP_2 PF07716.15 KKK18028.1 - 0.00011 22.1 11.0 0.00019 21.4 11.0 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 KKK18028.1 - 0.0021 18.6 9.3 0.0028 18.1 9.3 1.2 1 0 0 1 1 1 1 bZIP Maf transcription factor bZIP_1 PF00170.21 KKK18028.1 - 0.016 15.3 11.5 0.024 14.7 11.5 1.3 1 0 0 1 1 1 0 bZIP transcription factor Takusan PF04822.13 KKK18028.1 - 0.034 14.0 2.0 0.035 14.0 0.7 1.7 2 0 0 2 2 2 0 Takusan WD40_alt PF14077.6 KKK18028.1 - 0.083 12.8 0.2 0.2 11.6 0.1 1.7 1 1 0 1 1 1 0 Alternative WD40 repeat motif DivIC PF04977.15 KKK18028.1 - 0.46 10.3 4.5 0.17 11.6 1.3 1.8 1 1 1 2 2 2 0 Septum formation initiator Pan3_PK PF18101.1 KKK18029.1 - 7.8e-63 210.5 0.1 1.2e-62 209.9 0.1 1.3 1 0 0 1 1 1 1 Pan3 Pseudokinase domain Pkinase PF00069.25 KKK18029.1 - 8.8e-06 25.3 0.0 1.4e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain UBX PF00789.20 KKK18030.1 - 9.2e-10 38.6 0.0 1.9e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.6 KKK18030.1 - 4.4e-09 36.0 0.0 1.1e-08 34.8 0.0 1.7 1 0 0 1 1 1 1 UBA-like domain Atg14 PF10186.9 KKK18030.1 - 0.094 11.8 8.4 0.13 11.3 8.4 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 FUSC_2 PF13515.6 KKK18030.1 - 0.17 12.0 0.0 0.3 11.2 0.0 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein-like DUF1682 PF07946.14 KKK18030.1 - 0.74 9.0 8.5 1.2 8.3 8.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) LSM PF01423.22 KKK18031.1 - 6.8e-22 76.9 0.3 8.5e-22 76.6 0.3 1.1 1 0 0 1 1 1 1 LSM domain FoP_duplication PF13865.6 KKK18031.1 - 0.014 16.0 8.8 0.02 15.4 8.8 1.3 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 SM-ATX PF14438.6 KKK18031.1 - 0.056 13.6 0.0 0.073 13.2 0.0 1.3 1 0 0 1 1 1 0 Ataxin 2 SM domain Dioxygenase_C PF00775.21 KKK18033.1 - 1.7e-33 115.6 0.1 4.2e-32 111.0 0.1 2.1 1 1 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 KKK18033.1 - 1.3e-32 111.5 0.0 7.2e-32 109.1 0.0 2.0 2 0 0 2 2 2 1 Catechol dioxygenase N terminus EPL1 PF10513.9 KKK18034.1 - 0.0053 17.2 12.8 0.0053 17.2 12.8 2.5 3 0 0 3 3 3 1 Enhancer of polycomb-like Zn_clus PF00172.18 KKK18034.1 - 0.047 13.8 9.7 0.11 12.6 9.7 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain GREB1 PF15782.5 KKK18034.1 - 1.1 6.3 22.3 1.7 5.6 22.3 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer 5_nucleotid PF05761.14 KKK18034.1 - 3 6.6 7.7 5.1 5.9 7.7 1.3 1 0 0 1 1 1 0 5' nucleotidase family CYSTM PF12734.7 KKK18035.1 - 0.0027 18.0 44.3 0.0027 18.0 44.3 4.5 1 1 1 2 2 2 1 Cysteine-rich TM module stress tolerance Peptidase_M16 PF00675.20 KKK18036.1 - 1.7e-56 190.3 0.2 9.8e-56 187.9 0.3 2.2 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 KKK18036.1 - 1.8e-39 135.6 0.0 1.2e-37 129.7 0.0 2.3 2 0 0 2 2 2 1 Peptidase M16 inactive domain Epimerase PF01370.21 KKK18036.1 - 4e-19 69.0 0.0 7.4e-19 68.2 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KKK18036.1 - 3.9e-11 42.5 0.0 6e-11 41.9 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KKK18036.1 - 1.1e-10 41.5 0.0 1.9e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 KKK18036.1 - 1.5e-05 24.2 0.0 3.1e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.25 KKK18036.1 - 0.00047 19.7 0.0 0.0034 16.9 0.0 2.3 2 0 0 2 2 2 1 short chain dehydrogenase NAD_binding_10 PF13460.6 KKK18036.1 - 0.0064 16.4 0.0 0.017 15.0 0.0 1.7 1 0 0 1 1 1 1 NAD(P)H-binding Ldh_1_N PF00056.23 KKK18036.1 - 0.036 14.2 0.0 0.16 12.1 0.0 2.1 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain NAD_binding_4 PF07993.12 KKK18036.1 - 0.045 12.9 0.0 1.7 7.8 0.0 2.5 1 1 0 1 1 1 0 Male sterility protein Semialdhyde_dh PF01118.24 KKK18036.1 - 0.063 13.7 0.0 0.42 11.0 0.0 2.5 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain KR PF08659.10 KKK18036.1 - 0.088 12.7 0.0 0.34 10.8 0.0 1.9 2 0 0 2 2 2 0 KR domain PLAC8 PF04749.17 KKK18037.1 - 8e-23 81.3 8.0 9.4e-23 81.1 8.0 1.0 1 0 0 1 1 1 1 PLAC8 family Methyltr_RsmB-F PF01189.17 KKK18038.1 - 8.9e-31 107.1 0.0 5.5e-24 84.9 0.0 2.8 2 1 0 2 2 2 2 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 KKK18038.1 - 0.098 12.8 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase CD34_antigen PF06365.12 KKK18039.1 - 0.091 12.3 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 CD34/Podocalyxin family Vps39_2 PF10367.9 KKK18040.1 - 0.00094 19.6 0.0 0.0046 17.4 0.0 2.1 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.9 KKK18040.1 - 0.001 19.3 0.3 0.013 15.8 0.1 2.6 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 CASP_C PF08172.12 KKK18041.1 - 4.9e-91 304.6 2.5 4.9e-91 304.6 2.5 3.9 2 1 2 4 4 4 1 CASP C terminal MotB_plug PF13677.6 KKK18041.1 - 0.029 14.0 0.3 0.083 12.5 0.3 1.8 1 0 0 1 1 1 0 Membrane MotB of proton-channel complex MotA/MotB Peptidase_M16 PF00675.20 KKK18041.1 - 0.07 13.1 2.5 0.3 11.0 2.5 2.2 1 0 0 1 1 1 0 Insulinase (Peptidase family M16) ZapB PF06005.12 KKK18041.1 - 0.096 13.1 0.2 0.096 13.1 0.2 6.5 4 1 0 4 4 4 0 Cell division protein ZapB UPF0184 PF03670.13 KKK18041.1 - 0.45 10.9 11.9 1.2 9.6 0.5 4.2 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0184) SlyX PF04102.12 KKK18041.1 - 0.69 10.6 0.0 0.69 10.6 0.0 6.5 6 1 1 7 7 7 0 SlyX GIT_CC PF16559.5 KKK18041.1 - 3.8 7.5 16.7 0.55 10.1 1.0 4.4 4 1 0 4 4 4 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF3455 PF11937.8 KKK18042.1 - 2.4e-50 171.0 0.1 3.5e-50 170.5 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) DUF2990 PF11693.8 KKK18042.1 - 1.8e-22 79.3 1.2 4.2e-22 78.1 1.2 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2990) Fibrillarin PF01269.17 KKK18043.1 - 5.8e-104 346.1 0.0 7e-104 345.9 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.10 KKK18043.1 - 3.1e-06 27.0 0.1 5.4e-06 26.3 0.1 1.3 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.19 KKK18043.1 - 0.055 13.2 0.1 0.072 12.8 0.1 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 2-Hacid_dh_C PF02826.19 KKK18044.1 - 5e-55 185.6 0.0 7.9e-55 185.0 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Ribosomal_L22 PF00237.19 KKK18044.1 - 8.6e-41 138.3 0.1 2.4e-40 136.9 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L22p/L17e 2-Hacid_dh PF00389.30 KKK18044.1 - 1e-18 67.2 0.0 2e-18 66.3 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KKK18044.1 - 0.0012 19.1 0.2 0.0074 16.5 0.1 2.2 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase ADH_N PF08240.12 KKK18045.1 - 9.1e-28 96.3 0.1 1.4e-27 95.7 0.1 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain LPMO_10 PF03067.15 KKK18046.1 - 2.2e-10 41.5 0.3 2.2e-10 41.5 0.3 2.7 2 1 0 2 2 2 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading GAT PF03127.14 KKK18047.1 - 1e-18 67.4 0.1 5.1e-18 65.2 0.0 2.1 2 0 0 2 2 2 1 GAT domain HAUS6_N PF14661.6 KKK18047.1 - 0.18 11.3 3.7 0.2 11.2 0.6 2.1 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus Aminotran_1_2 PF00155.21 KKK18048.1 - 5.1e-17 62.1 0.0 6.1e-17 61.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Pectate_lyase_3 PF12708.7 KKK18049.1 - 1e-101 339.2 13.0 1.4e-87 293.1 10.4 2.5 2 0 0 2 2 2 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 KKK18049.1 - 1.1e-06 28.2 1.3 0.03 14.0 0.2 2.9 3 0 0 3 3 3 2 N terminal extension of bacteriophage endosialidase NosD PF05048.13 KKK18049.1 - 0.002 17.4 1.3 0.0044 16.3 1.3 1.5 1 0 0 1 1 1 1 Periplasmic copper-binding protein (NosD) Ank_2 PF12796.7 KKK18050.1 - 5.4e-40 135.9 2.8 1.3e-12 48.1 0.3 4.8 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KKK18050.1 - 3.2e-38 129.6 6.7 2.9e-12 46.8 0.3 7.1 5 2 2 7 7 7 5 Ankyrin repeats (many copies) Ank PF00023.30 KKK18050.1 - 6.5e-37 124.4 7.6 1e-06 28.9 0.2 9.1 8 0 0 8 8 8 7 Ankyrin repeat Ank_3 PF13606.6 KKK18050.1 - 5e-29 97.1 6.6 0.00012 22.2 0.1 9.1 9 0 0 9 9 9 6 Ankyrin repeat Ank_5 PF13857.6 KKK18050.1 - 1.8e-27 95.0 9.5 4.8e-07 29.9 0.6 6.7 4 3 2 6 6 6 5 Ankyrin repeats (many copies) CorA PF01544.18 KKK18050.1 - 1.3e-10 41.1 2.0 3.5e-10 39.7 1.7 1.7 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein PRP1_N PF06424.12 KKK18050.1 - 0.095 13.1 0.7 0.24 11.8 0.7 1.6 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal p12I PF12233.8 KKK18050.1 - 2.9 8.5 5.3 1.7 9.2 2.5 1.9 2 0 0 2 2 2 0 Human adult T cell leukemia/lymphoma virus protein adh_short PF00106.25 KKK18052.1 - 2.9e-45 154.2 0.7 3.7e-45 153.8 0.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KKK18052.1 - 8.7e-45 153.1 1.1 9.9e-45 152.9 1.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KKK18052.1 - 1.7e-12 47.6 0.5 2.4e-12 47.2 0.5 1.1 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 KKK18052.1 - 7.3e-05 22.3 0.7 0.00011 21.7 0.2 1.7 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KKK18052.1 - 0.00011 21.8 0.2 0.00024 20.7 0.2 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KKK18052.1 - 0.00014 21.8 0.2 0.0003 20.7 0.1 1.6 1 1 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 KKK18052.1 - 0.0047 16.1 0.1 0.0066 15.6 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein ACT_7 PF13840.6 KKK18052.1 - 0.038 13.8 0.3 0.33 10.8 0.1 2.4 2 0 0 2 2 2 0 ACT domain RmlD_sub_bind PF04321.17 KKK18052.1 - 0.042 12.9 0.0 0.064 12.4 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain Fungal_trans PF04082.18 KKK18053.1 - 1.5e-11 43.9 0.0 4.8e-09 35.6 0.0 2.4 2 1 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK18053.1 - 1.9e-06 27.9 7.0 3.5e-06 27.0 7.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mito_carr PF00153.27 KKK18081.1 - 1.5e-24 85.7 0.1 7.7e-24 83.4 0.0 1.8 2 0 0 2 2 2 1 Mitochondrial carrier protein GNAT_like PF18407.1 KKK18081.1 - 0.11 12.9 0.0 0.19 12.1 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyltransferase like domain Peptidase_C50 PF03568.17 KKK18082.1 - 1.9e-155 517.9 0.0 3.6e-155 516.9 0.0 1.5 1 0 0 1 1 1 1 Peptidase family C50 CHAT PF12770.7 KKK18082.1 - 3.3e-06 26.7 1.3 8.2e-05 22.1 0.0 3.3 4 0 0 4 4 4 1 CHAT domain TPR_12 PF13424.6 KKK18082.1 - 0.0046 17.2 20.4 2.6 8.4 0.0 6.2 5 2 1 7 7 7 3 Tetratricopeptide repeat TPR_2 PF07719.17 KKK18082.1 - 0.1 12.7 12.6 2 8.7 0.1 5.6 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_1 PF00515.28 KKK18082.1 - 0.44 10.4 2.4 20 5.2 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 KKK18082.1 - 2.8 8.7 4.6 97 3.7 0.0 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF5321 PF17254.2 KKK18083.1 - 5.4e-65 217.7 3.6 7.2e-65 217.3 3.6 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5321) DNA_alkylation PF08713.11 KKK18083.1 - 0.0039 16.9 0.7 0.0058 16.4 0.7 1.1 1 0 0 1 1 1 1 DNA alkylation repair enzyme FlgN PF05130.12 KKK18083.1 - 0.092 13.3 3.1 0.15 12.6 3.1 1.3 1 0 0 1 1 1 0 FlgN protein BRF1 PF07741.13 KKK18083.1 - 0.51 10.7 8.7 0.48 10.8 7.2 1.7 2 0 0 2 2 2 0 Brf1-like TBP-binding domain Peptidase_M22 PF00814.25 KKK18084.1 - 4.1e-46 157.9 0.0 1.6e-44 152.7 0.0 2.5 1 1 0 1 1 1 1 Glycoprotease family FGGY_C PF02782.16 KKK18084.1 - 0.042 13.6 0.0 0.08 12.7 0.0 1.4 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain YycC PF14174.6 KKK18084.1 - 0.1 12.4 0.1 0.28 11.0 0.1 1.7 1 0 0 1 1 1 0 YycC-like protein Esterase PF00756.20 KKK18085.1 - 7.9e-55 186.2 0.0 9.6e-55 185.9 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Esterase_phd PF10503.9 KKK18085.1 - 1.2e-05 25.0 0.0 0.00037 20.1 0.0 2.0 2 0 0 2 2 2 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 KKK18085.1 - 0.00024 20.7 0.1 0.00047 19.7 0.1 1.5 1 1 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KKK18085.1 - 0.0017 17.7 0.0 0.0029 16.9 0.0 1.7 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Lipase_3 PF01764.25 KKK18085.1 - 0.012 15.5 0.0 0.019 14.8 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) AXE1 PF05448.12 KKK18085.1 - 0.025 13.2 0.0 0.035 12.8 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) DLH PF01738.18 KKK18085.1 - 0.031 13.8 0.1 0.094 12.3 0.1 1.7 1 1 0 1 1 1 0 Dienelactone hydrolase family Chlorophyllase2 PF12740.7 KKK18085.1 - 0.051 12.5 0.0 0.12 11.3 0.0 1.6 1 1 0 1 1 1 0 Chlorophyllase enzyme PGAP1 PF07819.13 KKK18085.1 - 0.12 12.1 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein HMG_CoA_synt_C PF08540.10 KKK18086.1 - 8.9e-16 58.3 0.0 9.5e-16 58.2 0.0 1.0 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal zf-HC5HC2H_2 PF13832.6 KKK18088.1 - 5.7e-32 110.2 5.4 5.7e-32 110.2 5.4 2.3 2 0 0 2 2 2 1 PHD-zinc-finger like domain EPL1 PF10513.9 KKK18088.1 - 1.1e-31 110.3 0.1 3.5e-31 108.7 0.0 1.9 2 0 0 2 2 2 1 Enhancer of polycomb-like zf-HC5HC2H PF13771.6 KKK18088.1 - 3.1e-27 94.6 1.9 3.1e-27 94.6 1.9 2.9 3 0 0 3 3 3 1 PHD-like zinc-binding domain PHD_2 PF13831.6 KKK18088.1 - 1.8e-14 53.0 8.0 8.5e-14 50.8 2.3 2.6 2 0 0 2 2 2 2 PHD-finger PHD PF00628.29 KKK18088.1 - 3.7e-10 39.5 19.3 8.2e-09 35.2 9.5 2.6 2 0 0 2 2 2 2 PHD-finger zf-PHD-like PF15446.6 KKK18088.1 - 0.57 9.8 8.7 0.018 14.7 1.7 2.0 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain zf-RING-like PF08746.11 KKK18088.1 - 3.6 8.0 18.8 0.029 14.7 3.7 2.6 2 0 0 2 2 2 0 RING-like domain RRM_1 PF00076.22 KKK18089.1 - 3.6e-21 74.8 0.0 4.8e-21 74.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KKK18089.1 - 7.9e-05 22.2 0.0 0.00011 21.8 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AA_permease PF00324.21 KKK18098.1 - 1.8e-142 475.3 37.4 2.1e-142 475.1 37.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KKK18098.1 - 7.2e-30 104.2 39.5 9.7e-30 103.7 39.5 1.1 1 0 0 1 1 1 1 Amino acid permease DUF4781 PF16013.5 KKK18098.1 - 0.014 14.2 0.3 0.027 13.3 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4781) RhoGAP PF00620.27 KKK18099.1 - 7.9e-16 58.2 0.1 1.7e-15 57.2 0.1 1.5 1 0 0 1 1 1 1 RhoGAP domain DEP PF00610.21 KKK18099.1 - 4e-11 42.8 0.0 7.9e-11 41.9 0.0 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) FCH PF00611.23 KKK18099.1 - 3.2e-07 30.5 0.0 1.1e-06 28.8 0.0 2.0 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain DUF5343 PF17278.2 KKK18099.1 - 0.14 12.2 0.1 0.29 11.2 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5343) AAA PF00004.29 KKK18100.1 - 2.4e-13 50.6 0.0 7e-13 49.2 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KKK18100.1 - 4e-12 46.9 0.3 1.8e-11 44.7 0.3 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KKK18100.1 - 5.7e-11 42.8 0.0 1.6e-10 41.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain Cdc6_C PF09079.11 KKK18100.1 - 8.6e-08 32.1 0.1 4.5e-07 29.7 0.1 2.2 1 1 0 1 1 1 1 CDC6, C terminal winged helix domain DUF2075 PF09848.9 KKK18100.1 - 0.00034 20.0 0.0 0.00062 19.1 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_11 PF13086.6 KKK18100.1 - 0.0013 18.6 0.5 0.07 12.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_lid_10 PF17872.1 KKK18100.1 - 0.0014 18.7 0.0 0.003 17.7 0.0 1.4 1 0 0 1 1 1 1 AAA lid domain AAA_7 PF12775.7 KKK18100.1 - 0.0016 18.0 0.0 0.0037 16.8 0.0 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_19 PF13245.6 KKK18100.1 - 0.0047 17.3 0.0 0.0095 16.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 KKK18100.1 - 0.013 14.6 0.0 0.028 13.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) PIF1 PF05970.14 KKK18100.1 - 0.027 13.7 0.0 0.043 13.0 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase NTPase_1 PF03266.15 KKK18100.1 - 0.032 14.2 0.0 0.061 13.2 0.0 1.5 1 0 0 1 1 1 0 NTPase TIP49 PF06068.13 KKK18100.1 - 0.036 13.3 0.0 0.067 12.4 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain ATPase_2 PF01637.18 KKK18100.1 - 0.039 13.9 0.0 0.085 12.8 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea NACHT PF05729.12 KKK18100.1 - 0.043 13.7 0.1 0.11 12.4 0.1 1.7 1 1 0 1 1 1 0 NACHT domain ABC_tran PF00005.27 KKK18100.1 - 0.049 14.1 0.0 0.18 12.3 0.0 2.0 2 0 0 2 2 1 0 ABC transporter AAA_5 PF07728.14 KKK18100.1 - 0.075 13.0 0.0 0.22 11.5 0.0 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 KKK18100.1 - 0.1 12.8 0.0 0.45 10.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KKK18100.1 - 0.11 12.7 0.0 0.35 11.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 KKK18100.1 - 0.13 11.4 0.0 0.24 10.5 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Pkinase PF00069.25 KKK18101.1 - 3.4e-30 105.3 0.0 3.7e-30 105.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK18101.1 - 8.3e-21 74.4 0.0 9.3e-21 74.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase ABC1 PF03109.16 KKK18101.1 - 0.0082 16.3 0.0 0.012 15.8 0.0 1.3 1 0 0 1 1 1 1 ABC1 family Thioredoxin_7 PF13899.6 KKK18102.1 - 8e-17 61.2 0.0 1.6e-16 60.3 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like UBA_4 PF14555.6 KKK18102.1 - 1.2e-14 53.8 0.1 2.6e-14 52.8 0.1 1.5 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.20 KKK18102.1 - 2.4e-05 24.4 0.1 0.00014 22.0 0.0 2.3 3 0 0 3 3 3 1 UBX domain Thioredoxin_2 PF13098.6 KKK18102.1 - 0.019 15.4 0.0 0.039 14.4 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like domain TAP_C PF03943.13 KKK18102.1 - 0.079 12.6 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 TAP C-terminal domain Thioredox_DsbH PF03190.15 KKK18102.1 - 0.14 12.2 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF255 Methyltransf_23 PF13489.6 KKK18122.1 - 3.7e-15 56.1 0.0 6e-15 55.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKK18122.1 - 1.4e-07 32.2 0.0 5.2e-07 30.3 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KKK18122.1 - 3.4e-05 24.5 0.0 9e-05 23.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KKK18122.1 - 0.00013 22.5 0.0 0.00053 20.6 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KKK18122.1 - 0.00013 21.8 0.0 0.00027 20.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 KKK18122.1 - 0.00034 20.8 0.0 0.00071 19.7 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase MTS PF05175.14 KKK18122.1 - 0.0013 18.3 0.0 0.0023 17.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 KKK18122.1 - 0.0016 18.0 0.0 0.0034 16.9 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase PrmA PF06325.13 KKK18122.1 - 0.07 12.5 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.18 KKK18122.1 - 0.11 11.7 0.0 0.65 9.3 0.0 2.1 2 1 0 2 2 2 0 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.18 KKK18122.1 - 0.13 11.5 0.1 0.35 10.1 0.0 1.6 2 0 0 2 2 2 0 O-methyltransferase domain CMAS PF02353.20 KKK18122.1 - 0.14 11.4 0.0 0.26 10.5 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Glyoxalase PF00903.25 KKK18127.1 - 5.3e-32 110.7 0.0 1.2e-15 57.8 0.0 2.7 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Fungal_trans PF04082.18 KKK18127.1 - 1.2e-15 57.2 0.0 2.7e-15 56.1 0.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Glyoxalase_4 PF13669.6 KKK18127.1 - 5.2e-10 39.6 0.0 0.0014 18.9 0.0 3.7 2 2 1 3 3 3 3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 KKK18127.1 - 0.0033 17.6 0.0 1.3 9.1 0.0 2.9 3 0 0 3 3 3 2 Glyoxalase-like domain Glyoxalase_6 PF18029.1 KKK18127.1 - 0.012 16.4 0.0 1.2 10.0 0.0 3.4 3 0 0 3 3 3 0 Glyoxalase-like domain Glyoxalase_2 PF12681.7 KKK18127.1 - 0.96 9.4 2.5 61 3.6 0.0 3.5 4 0 0 4 4 4 0 Glyoxalase-like domain NMDAR2_C PF10565.9 KKK18129.1 - 0.073 12.0 0.4 0.082 11.8 0.4 1.0 1 0 0 1 1 1 0 N-methyl D-aspartate receptor 2B3 C-terminus DUF3435 PF11917.8 KKK18131.1 - 1.2e-11 44.2 0.0 1.6e-11 43.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) WD40 PF00400.32 KKK18158.1 - 1.1e-33 114.6 33.2 1.5e-06 28.8 3.9 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKK18158.1 - 2.6e-17 62.9 0.2 8.3e-05 22.8 0.0 5.7 2 1 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KKK18158.1 - 0.00069 19.6 0.1 0.31 10.9 0.1 2.6 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Frtz PF11768.8 KKK18158.1 - 0.023 13.0 0.0 0.17 10.2 0.0 1.9 1 1 2 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz DEC-1_N PF04625.13 KKK18158.1 - 4.3 6.2 9.7 7.1 5.5 9.7 1.3 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region MBOAT PF03062.19 KKK18159.1 - 1.1e-27 97.3 12.0 1.6e-27 96.8 12.0 1.1 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 KKK18159.1 - 0.63 10.4 5.4 0.51 10.7 2.9 2.1 2 0 0 2 2 2 0 Membrane bound O-acyl transferase family Tmemb_170 PF10190.9 KKK18161.1 - 1.4e-23 83.3 8.2 1.6e-23 83.1 8.2 1.0 1 0 0 1 1 1 1 Putative transmembrane protein 170 TFIIE_alpha PF02002.17 KKK18162.1 - 2.8e-19 68.9 0.0 6.8e-19 67.7 0.0 1.7 1 0 0 1 1 1 1 TFIIE alpha subunit HTH_Crp_2 PF13545.6 KKK18162.1 - 0.021 14.8 0.2 0.039 13.9 0.2 1.5 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain Zn-ribbon_8 PF09723.10 KKK18162.1 - 0.052 13.7 0.4 0.22 11.7 0.4 2.0 1 1 1 2 2 2 0 Zinc ribbon domain TF_Zn_Ribbon PF08271.12 KKK18162.1 - 0.054 13.0 2.0 0.84 9.2 2.0 2.5 1 1 1 2 2 2 0 TFIIB zinc-binding DUF2462 PF09495.10 KKK18162.1 - 0.14 12.9 2.3 0.42 11.4 2.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2462) DUF3517 PF12030.8 KKK18163.1 - 6.4e-105 350.8 0.0 1.1e-104 350.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3517) UCH PF00443.29 KKK18163.1 - 4.1e-41 141.2 0.3 7.5e-41 140.3 0.3 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KKK18163.1 - 1.1e-22 81.0 0.1 2.3e-22 80.0 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Sec23_helical PF04815.15 KKK18163.1 - 0.12 12.2 0.0 0.78 9.6 0.0 2.5 1 0 0 1 1 1 0 Sec23/Sec24 helical domain PseudoU_synth_1 PF01416.20 KKK18164.1 - 6.5e-11 42.6 0.0 2.4e-09 37.6 0.0 2.5 2 0 0 2 2 2 1 tRNA pseudouridine synthase Mac PF12464.8 KKK18165.1 - 4e-13 49.4 0.1 6.3e-13 48.8 0.1 1.3 1 0 0 1 1 1 1 Maltose acetyltransferase Hexapep PF00132.24 KKK18165.1 - 4.2e-13 48.5 7.7 3.6e-10 39.2 3.4 3.3 3 0 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KKK18165.1 - 4.8e-11 42.2 7.0 1.3e-08 34.4 3.1 3.2 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase ICMT PF04140.14 KKK18166.1 - 2.7e-28 98.2 0.5 2.7e-28 98.2 0.5 1.6 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 KKK18166.1 - 1e-12 48.4 1.5 2.3e-12 47.2 1.5 1.6 1 0 0 1 1 1 1 Phospholipid methyltransferase DUF1295 PF06966.12 KKK18166.1 - 0.0003 20.4 0.7 0.00043 19.9 0.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) NnrU PF07298.11 KKK18166.1 - 0.0046 16.5 6.5 0.0074 15.8 6.5 1.4 1 0 0 1 1 1 1 NnrU protein OMPdecase PF00215.24 KKK18167.1 - 2.6e-77 259.4 0.0 3.6e-77 259.0 0.0 1.2 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family MAPEG PF01124.18 KKK18167.1 - 1.3e-23 83.3 0.2 2.1e-23 82.6 0.2 1.3 1 0 0 1 1 1 1 MAPEG family Mlf1IP PF10248.9 KKK18169.1 - 2.4 8.1 6.9 1.1 9.3 3.4 1.9 2 0 0 2 2 2 0 Myelodysplasia-myeloid leukemia factor 1-interacting protein MFS_MOT1 PF16983.5 KKK18170.1 - 9.9e-59 196.6 37.8 6.8e-33 113.4 11.1 2.8 3 0 0 3 3 3 2 Molybdate transporter of MFS superfamily Sulfate_transp PF00916.20 KKK18170.1 - 0.011 14.6 24.7 33 3.1 24.7 3.2 1 1 0 1 1 1 0 Sulfate permease family UTP15_C PF09384.10 KKK18171.1 - 2.7e-52 176.4 1.0 4.7e-52 175.6 1.0 1.4 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.32 KKK18171.1 - 1.3e-20 73.3 5.9 0.00015 22.5 0.0 5.4 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKK18171.1 - 1.6e-09 37.9 0.7 0.01 16.1 0.0 5.0 4 2 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain RAB3GAP2_N PF14655.6 KKK18171.1 - 0.091 12.0 0.4 2.4 7.3 0.1 2.2 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus CCDC-167 PF15188.6 KKK18171.1 - 0.096 13.0 2.3 0.24 11.8 2.3 1.6 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 PVL_ORF50 PF07768.11 KKK18171.1 - 0.11 12.8 2.3 0.31 11.4 2.3 1.7 1 0 0 1 1 1 0 PVL ORF-50-like family PhyH PF05721.13 KKK18172.1 - 4e-44 151.4 0.0 1e-41 143.5 0.0 2.1 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) C2 PF00168.30 KKK18173.1 - 1.2e-15 57.7 0.0 2.2e-15 56.8 0.0 1.5 1 0 0 1 1 1 1 C2 domain DUF3439 PF11921.8 KKK18173.1 - 2.1 8.3 7.1 4.9 7.1 7.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Ank_2 PF12796.7 KKK18174.1 - 3.4e-28 98.1 0.9 2.8e-12 47.1 0.0 4.8 3 2 2 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KKK18174.1 - 1.7e-23 82.6 2.5 3.5e-10 40.2 0.1 6.3 5 2 2 7 7 7 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KKK18174.1 - 5.2e-18 63.3 0.9 2e-05 24.6 0.1 7.9 8 0 0 8 8 8 2 Ankyrin repeat Ank_5 PF13857.6 KKK18174.1 - 2.8e-14 53.0 0.9 1.2e-07 31.8 0.1 4.6 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 KKK18174.1 - 1.3e-11 44.4 4.1 2.8e-05 24.4 0.1 4.9 5 0 0 5 5 5 2 Ankyrin repeat RRM_occluded PF16842.5 KKK18175.1 - 5.9e-32 109.4 0.0 1.1e-31 108.6 0.0 1.4 1 0 0 1 1 1 1 Occluded RNA-recognition motif RRM_1 PF00076.22 KKK18175.1 - 3.6e-05 23.5 0.0 6.6e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Lsm_interact PF05391.11 KKK18175.1 - 0.0092 15.4 2.4 0.022 14.2 2.4 1.6 1 0 0 1 1 1 1 Lsm interaction motif TMEM234 PF10639.9 KKK18177.1 - 9.4e-26 90.1 1.0 1.4e-25 89.5 1.0 1.3 1 0 0 1 1 1 1 Putative transmembrane family 234 PRIMA1 PF16101.5 KKK18177.1 - 0.19 11.8 8.3 0.059 13.4 5.6 1.6 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 CAP_N PF01213.19 KKK18177.1 - 1.4 8.3 6.7 1.7 8.0 6.7 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Chitin_synth_1 PF01644.17 KKK18178.1 - 2.5e-75 251.9 0.0 3.8e-75 251.3 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 KKK18178.1 - 3.6e-29 100.5 0.0 7.3e-29 99.5 0.0 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 KKK18178.1 - 2.5e-21 75.9 2.3 2.7e-17 62.6 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase DUF4199 PF13858.6 KKK18178.1 - 6.4 7.1 21.9 0.2 12.0 14.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF4199) Pkinase PF00069.25 KKK18179.1 - 1.3e-29 103.4 0.0 5.9e-14 52.1 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KKK18179.1 - 2.9e-07 30.0 0.0 0.0094 15.3 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 KKK18179.1 - 0.054 13.4 0.0 0.11 12.4 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family LMWPc PF01451.21 KKK18180.1 - 7.8e-33 113.8 0.0 1e-32 113.4 0.0 1.2 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase COQ7 PF03232.13 KKK18181.1 - 8.9e-70 233.9 0.8 1.1e-69 233.7 0.8 1.1 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Rubrerythrin PF02915.17 KKK18181.1 - 8.3e-06 26.2 0.2 8.5e-05 23.0 0.0 2.0 1 1 1 2 2 2 1 Rubrerythrin Crr6 PF08847.11 KKK18181.1 - 0.0057 16.3 0.1 0.25 11.0 0.0 2.2 1 1 1 2 2 2 2 Chlororespiratory reduction 6 DUF4455 PF14643.6 KKK18181.1 - 0.031 12.9 0.1 0.046 12.4 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4455) SPT2 PF08243.11 KKK18181.1 - 0.1 13.1 4.7 0.17 12.4 4.7 1.2 1 0 0 1 1 1 0 SPT2 chromatin protein Plus-3 PF03126.18 KKK18182.1 - 3.6e-32 111.1 0.0 4.1e-31 107.7 0.0 2.5 2 0 0 2 2 2 1 Plus-3 domain MRC1 PF09444.10 KKK18183.1 - 1.4e-41 142.4 20.0 1.4e-41 142.4 20.0 6.9 7 0 0 7 7 7 2 MRC1-like domain BUD22 PF09073.10 KKK18183.1 - 0.00042 19.8 18.5 0.00042 19.8 18.5 6.0 3 2 1 4 4 4 1 BUD22 Nuc_deoxyri_tr3 PF11071.8 KKK18183.1 - 0.094 12.8 0.2 0.26 11.4 0.2 1.7 1 0 0 1 1 1 0 Nucleoside 2-deoxyribosyltransferase YtoQ KR PF08659.10 KKK18183.1 - 0.48 10.3 4.8 2.1 8.2 1.1 2.5 2 0 0 2 2 2 0 KR domain CorA PF01544.18 KKK18192.1 - 3.4e-38 131.6 0.1 5.8e-38 130.9 0.1 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Fungal_trans PF04082.18 KKK18221.1 - 5.3e-14 51.9 0.0 1e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain FAD_binding_3 PF01494.19 KKK18222.1 - 3.8e-17 62.6 0.2 2.3e-07 30.4 0.0 3.1 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.24 KKK18222.1 - 0.0002 21.1 0.0 0.24 10.9 0.0 2.1 1 1 1 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KKK18222.1 - 0.00024 20.5 0.0 0.00039 19.8 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 KKK18222.1 - 0.0016 17.6 0.0 0.038 13.0 0.0 2.1 2 0 0 2 2 2 1 Squalene epoxidase NAD_binding_8 PF13450.6 KKK18222.1 - 0.0018 18.5 0.0 0.004 17.4 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KKK18222.1 - 0.15 12.0 0.0 0.28 11.2 0.0 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding Myb_DNA-binding PF00249.31 KKK18223.1 - 3.9e-30 103.8 10.7 2e-11 43.9 1.1 3.5 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KKK18223.1 - 2.1e-27 95.1 8.0 3.2e-13 49.7 2.4 3.3 3 0 0 3 3 3 3 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 KKK18223.1 - 0.00022 21.3 0.2 0.00022 21.3 0.2 2.9 2 1 0 3 3 3 1 SANT/Myb-like domain of DAMP1 MADF_DNA_bdg PF10545.9 KKK18223.1 - 0.00071 19.9 1.6 0.49 10.8 0.2 2.7 2 0 0 2 2 2 2 Alcohol dehydrogenase transcription factor Myb/SANT-like HsbA PF12296.8 KKK18224.1 - 4.5e-24 85.2 12.0 4.5e-24 85.2 12.0 2.4 2 0 0 2 2 2 1 Hydrophobic surface binding protein A Fungal_trans PF04082.18 KKK18225.1 - 4.9e-20 71.7 0.4 6.8e-20 71.2 0.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Cutinase PF01083.22 KKK18226.1 - 8.2e-48 162.7 1.6 9.5e-48 162.5 1.6 1.0 1 0 0 1 1 1 1 Cutinase VirJ PF06057.11 KKK18226.1 - 0.0003 20.7 0.0 0.00036 20.5 0.0 1.1 1 0 0 1 1 1 1 Bacterial virulence protein (VirJ) PE-PPE PF08237.11 KKK18226.1 - 0.0012 18.4 0.1 0.0017 18.0 0.1 1.2 1 0 0 1 1 1 1 PE-PPE domain LVIVD PF08309.11 KKK18227.1 - 7.4e-10 38.0 1.6 0.32 10.4 0.0 5.3 5 0 0 5 5 5 5 LVIVD repeat Brr6_like_C_C PF10104.9 KKK18228.1 - 3.2e-44 149.9 0.2 4.2e-44 149.6 0.2 1.1 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain Lipase_GDSL_2 PF13472.6 KKK18229.1 - 2.3e-13 50.9 3.4 8.7e-13 49.1 3.4 1.9 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KKK18229.1 - 1e-09 38.7 0.0 1.4e-09 38.2 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.6 KKK18229.1 - 0.0077 16.4 0.0 0.013 15.7 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Ank_2 PF12796.7 KKK18230.1 - 4e-34 117.0 0.0 1.3e-14 54.5 0.0 4.1 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KKK18230.1 - 3.5e-26 88.4 0.5 0.00065 20.0 0.0 7.3 7 0 0 7 7 7 6 Ankyrin repeat Ank_4 PF13637.6 KKK18230.1 - 1.4e-25 89.3 1.1 3.2e-06 27.6 0.0 5.5 2 1 4 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 KKK18230.1 - 2.2e-23 82.0 5.9 2.5e-08 34.0 0.0 5.4 5 1 1 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.30 KKK18230.1 - 1e-21 76.3 0.3 0.00055 20.3 0.0 7.0 7 0 0 7 7 7 5 Ankyrin repeat F-box-like PF12937.7 KKK18230.1 - 0.021 14.7 0.0 0.051 13.5 0.0 1.7 1 0 0 1 1 1 0 F-box-like F-box PF00646.33 KKK18230.1 - 0.19 11.7 0.1 0.34 10.8 0.1 1.4 1 0 0 1 1 1 0 F-box domain DUF2202 PF09968.9 KKK18231.1 - 0.014 15.2 0.3 0.023 14.6 0.3 1.3 1 0 0 1 1 1 0 Uncharacterized protein domain (DUF2202) DUF1811 PF08838.10 KKK18231.1 - 0.023 14.9 0.2 0.039 14.2 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1811) Par3_HAL_N_term PF12053.8 KKK18231.1 - 0.21 11.8 0.1 0.21 11.8 0.1 1.7 1 1 1 2 2 2 0 N-terminal of Par3 and HAL proteins DUF2076 PF09849.9 KKK18233.1 - 6.5e-05 23.1 2.9 6.5e-05 23.1 2.9 3.1 2 1 1 3 3 3 1 Uncharacterized protein conserved in bacteria (DUF2076) Peptidase_C26 PF07722.13 KKK18233.1 - 0.12 12.1 0.4 0.18 11.5 0.4 1.2 1 0 0 1 1 1 0 Peptidase C26 ATP-synt_E PF05680.12 KKK18233.1 - 4 7.9 6.7 0.91 9.9 0.3 2.2 2 0 0 2 2 2 0 ATP synthase E chain Methyltransf_31 PF13847.6 KKK18235.1 - 2e-27 95.9 0.0 2.6e-27 95.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKK18235.1 - 6.3e-23 81.3 0.0 1e-22 80.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KKK18235.1 - 7.1e-23 81.1 0.0 1.1e-22 80.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KKK18235.1 - 5.7e-16 58.6 0.0 7.9e-16 58.1 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 KKK18235.1 - 3.2e-15 56.7 0.0 4.7e-15 56.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KKK18235.1 - 2.8e-13 50.0 0.0 3.5e-13 49.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 KKK18235.1 - 4.8e-09 36.1 0.0 7e-09 35.5 0.0 1.1 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW PCMT PF01135.19 KKK18235.1 - 2.1e-08 34.2 0.0 2.9e-08 33.7 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 KKK18235.1 - 6.2e-06 25.9 0.0 9.1e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain DREV PF05219.12 KKK18235.1 - 1.1e-05 24.7 0.0 1.5e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 DREV methyltransferase NodS PF05401.11 KKK18235.1 - 5.1e-05 23.0 0.0 7.5e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_4 PF02390.17 KKK18235.1 - 6.9e-05 22.4 0.0 9.3e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_9 PF08003.11 KKK18235.1 - 0.00027 20.0 0.0 0.00038 19.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) RrnaAD PF00398.20 KKK18235.1 - 0.005 15.9 0.0 0.0068 15.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_29 PF03141.16 KKK18235.1 - 0.0052 15.4 0.0 0.0065 15.1 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_2 PF00891.18 KKK18235.1 - 0.0075 15.6 0.0 0.01 15.1 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase domain Methyltr_RsmB-F PF01189.17 KKK18235.1 - 0.027 14.1 0.0 0.039 13.6 0.0 1.2 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F CMAS PF02353.20 KKK18235.1 - 0.039 13.2 0.0 0.05 12.9 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.7 KKK18235.1 - 0.056 13.4 0.0 0.088 12.7 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Flavoprotein PF02441.19 KKK18236.1 - 4.6e-25 88.2 0.1 5.7e-25 87.9 0.1 1.1 1 0 0 1 1 1 1 Flavoprotein Na_Ca_ex PF01699.24 KKK18237.1 - 4.1e-33 114.5 43.8 1.7e-19 70.2 17.4 3.0 2 1 0 2 2 2 2 Sodium/calcium exchanger protein DUF5589 PF17672.1 KKK18237.1 - 1 9.3 2.9 1.1 9.1 0.1 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5589) UbiD PF01977.16 KKK18238.1 - 4.3e-118 394.7 0.0 5e-118 394.5 0.0 1.0 1 0 0 1 1 1 1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase DUF3756 PF12581.8 KKK18238.1 - 0.15 11.9 0.1 22 5.0 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3756) EthD PF07110.11 KKK18278.1 - 2.9e-22 79.6 1.1 3.4e-22 79.4 1.1 1.1 1 0 0 1 1 1 1 EthD domain MmlI PF09448.10 KKK18278.1 - 0.012 16.0 0.1 0.016 15.6 0.1 1.2 1 0 0 1 1 1 0 Methylmuconolactone methyl-isomerase CBS PF00571.28 KKK18281.1 - 8.4e-06 26.1 0.0 0.53 10.8 0.0 3.3 2 1 1 3 3 3 3 CBS domain VMA21 PF09446.10 KKK18282.1 - 1.8e-10 40.7 18.2 7.6e-10 38.8 18.2 1.8 1 1 0 1 1 1 1 VMA21-like domain MS_channel PF00924.18 KKK18282.1 - 0.013 15.0 2.5 0.018 14.6 2.5 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel DUF2681 PF10883.8 KKK18282.1 - 0.016 15.6 0.2 0.025 15.0 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) Trp_oprn_chp PF09534.10 KKK18282.1 - 0.027 14.3 0.5 0.22 11.3 0.5 1.9 1 1 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Saf_2TM PF18303.1 KKK18282.1 - 0.069 12.7 0.1 0.093 12.3 0.1 1.2 1 0 0 1 1 1 0 SAVED-fused 2TM effector domain Vpu PF00558.19 KKK18282.1 - 0.14 11.9 0.9 0.22 11.3 0.0 1.6 2 0 0 2 2 2 0 Vpu protein Sugar_tr PF00083.24 KKK18283.1 - 3.8e-95 319.4 28.9 4.4e-95 319.2 28.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKK18283.1 - 2.4e-27 95.8 46.9 2.4e-24 85.9 21.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KKK18283.1 - 0.00059 18.4 1.6 0.00059 18.4 1.6 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) SNF2_N PF00176.23 KKK18284.1 - 3.4e-56 190.5 0.4 5.5e-56 189.8 0.4 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KKK18284.1 - 1.5e-19 70.4 0.6 1.3e-18 67.4 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KKK18284.1 - 1.3e-09 38.3 0.0 2.9e-09 37.2 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KKK18284.1 - 8.4e-06 25.7 0.0 1.9e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase ERCC3_RAD25_C PF16203.5 KKK18284.1 - 1e-05 24.9 0.1 2e-05 23.9 0.1 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase HHH_3 PF12836.7 KKK18284.1 - 0.011 16.0 0.0 0.025 14.8 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif HIGH_NTase1_ass PF16581.5 KKK18284.1 - 0.034 14.1 0.0 0.11 12.5 0.0 1.8 2 0 0 2 2 2 0 Cytidyltransferase-related C-terminal region CLP_protease PF00574.23 KKK18285.1 - 2.8e-76 255.5 0.0 3.5e-76 255.2 0.0 1.1 1 0 0 1 1 1 1 Clp protease Tugs PF17840.1 KKK18285.1 - 0.063 13.5 1.3 0.17 12.1 1.3 1.7 1 0 0 1 1 1 0 Tethering Ubl4a to BAGS domain Peptidase_S49 PF01343.18 KKK18285.1 - 0.071 13.1 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Peptidase family S49 Hydrolase_like PF13242.6 KKK18287.1 - 3.4e-15 55.8 0.0 2.5e-14 53.1 0.0 2.1 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.26 KKK18287.1 - 5.8e-07 30.0 0.0 8.4e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 KKK18287.1 - 0.0024 18.0 0.2 0.021 15.0 0.0 2.3 1 1 1 2 2 2 1 Haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KKK18287.1 - 0.0093 16.1 0.0 0.019 15.0 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Rep_fac_C PF08542.11 KKK18288.1 - 6.5e-19 68.1 0.1 2.3e-18 66.4 0.1 2.0 1 0 0 1 1 1 1 Replication factor C C-terminal domain Sec20 PF03908.13 KKK18288.1 - 1.4e-16 60.2 1.0 1.4e-16 60.2 1.0 2.3 3 0 0 3 3 1 1 Sec20 AAA PF00004.29 KKK18288.1 - 1.8e-14 54.3 0.0 7.1e-14 52.4 0.0 2.1 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 KKK18288.1 - 7.6e-13 48.6 0.0 1.1e-11 44.8 0.0 2.5 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.15 KKK18288.1 - 6.7e-09 35.9 0.0 1.7e-08 34.6 0.0 1.7 1 1 0 1 1 1 1 Rad17 P-loop domain RuvB_N PF05496.12 KKK18288.1 - 3.6e-05 23.6 0.1 0.00013 21.8 0.0 2.0 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_assoc_2 PF16193.5 KKK18288.1 - 0.00016 21.9 1.4 0.00093 19.5 0.1 2.8 2 0 0 2 2 2 1 AAA C-terminal domain AAA_11 PF13086.6 KKK18288.1 - 0.00076 19.3 0.0 0.00076 19.3 0.0 3.1 3 1 0 3 3 3 1 AAA domain AAA_22 PF13401.6 KKK18288.1 - 0.00076 19.8 0.0 0.0083 16.4 0.0 2.6 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 KKK18288.1 - 0.00095 18.6 0.0 0.029 13.7 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 KKK18288.1 - 0.0031 17.9 0.0 0.0031 17.9 0.0 3.9 3 2 1 4 4 4 1 AAA ATPase domain AAA_24 PF13479.6 KKK18288.1 - 0.015 15.1 0.0 0.039 13.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain DNA_pol3_delta PF06144.13 KKK18288.1 - 0.015 15.1 0.0 0.045 13.5 0.0 1.7 1 0 0 1 1 1 0 DNA polymerase III, delta subunit AAA_19 PF13245.6 KKK18288.1 - 0.019 15.3 0.0 0.093 13.1 0.0 2.2 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 KKK18288.1 - 0.027 15.0 8.2 0.088 13.3 0.0 3.3 2 1 0 2 2 1 0 AAA domain AAA_7 PF12775.7 KKK18288.1 - 0.034 13.7 0.0 0.062 12.8 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_5 PF07728.14 KKK18288.1 - 0.045 13.8 0.1 0.46 10.5 0.1 2.5 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) DEAD PF00270.29 KKK18288.1 - 0.065 13.0 0.0 0.39 10.5 0.0 2.3 2 0 0 2 2 2 0 DEAD/DEAH box helicase AAA_18 PF13238.6 KKK18288.1 - 0.066 13.8 0.0 0.27 11.8 0.0 2.1 1 1 0 1 1 1 0 AAA domain ResIII PF04851.15 KKK18288.1 - 0.096 12.7 0.1 0.79 9.7 0.0 2.6 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit AAA_28 PF13521.6 KKK18288.1 - 0.24 11.6 2.8 0.63 10.3 0.0 2.9 2 1 1 3 3 3 0 AAA domain MutS_II PF05188.17 KKK18288.1 - 0.74 10.1 4.3 1.4 9.2 3.6 1.9 1 1 0 1 1 1 0 MutS domain II Mito_carr PF00153.27 KKK18289.1 - 1e-45 153.6 5.8 3.5e-16 58.9 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF3602 PF12223.8 KKK18290.1 - 7.9e-18 64.8 6.1 8.3e-17 61.6 0.4 3.0 1 1 2 3 3 3 2 Protein of unknown function (DUF3602) Ribosomal_L35Ae PF01247.18 KKK18291.1 - 1.1e-41 140.9 0.3 1.3e-41 140.7 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 KKK18291.1 - 0.002 18.3 0.1 1.2 9.4 0.0 2.2 2 0 0 2 2 2 2 RimM N-terminal domain DUF2080 PF09853.9 KKK18291.1 - 0.015 15.0 0.8 0.12 12.1 0.1 2.1 1 1 1 2 2 2 0 Putative transposon-encoded protein (DUF2080) G6PD_C PF02781.16 KKK18292.1 - 1.4e-115 385.5 0.0 2.3e-115 384.8 0.0 1.3 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 KKK18292.1 - 1.8e-60 204.6 0.0 3.1e-60 203.8 0.0 1.4 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain DUF5617 PF18493.1 KKK18292.1 - 0.18 11.9 0.2 0.46 10.6 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5617) DUF2406 PF10295.9 KKK18293.1 - 7.9e-27 93.7 7.4 4.3e-26 91.4 0.0 3.5 3 0 0 3 3 3 1 Uncharacterised protein (DUF2406) Glypican PF01153.19 KKK18293.1 - 2 7.1 4.3 3.9 6.2 4.3 1.3 1 0 0 1 1 1 0 Glypican DivIC PF04977.15 KKK18293.1 - 3.2 7.6 6.9 0.82 9.5 3.5 1.7 2 0 0 2 2 2 0 Septum formation initiator CDK2AP PF09806.9 KKK18293.1 - 3.3 7.7 11.4 0.39 10.8 5.1 2.1 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein 4HBT_2 PF13279.6 KKK18294.1 - 0.005 17.3 0.1 0.012 16.1 0.1 1.7 1 1 0 1 1 1 1 Thioesterase-like superfamily MFS_2 PF13347.6 KKK18295.1 - 5.8e-11 41.6 11.9 5.8e-11 41.6 11.9 2.0 2 0 0 2 2 2 1 MFS/sugar transport protein MFS_1_like PF12832.7 KKK18295.1 - 0.00027 19.9 1.7 0.001 18.0 1.6 2.1 1 1 0 1 1 1 1 MFS_1 like family FancD2 PF14631.6 KKK18295.1 - 0.07 10.5 0.0 3 5.1 0.0 2.0 2 0 0 2 2 2 0 Fanconi anaemia protein FancD2 nuclease DUF1708 PF08101.11 KKK18296.1 - 3.9e-171 570.0 0.0 6.3e-171 569.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1708) RhoGAP PF00620.27 KKK18296.1 - 0.011 15.6 0.0 0.045 13.6 0.0 1.9 2 0 0 2 2 2 0 RhoGAP domain NmrA PF05368.13 KKK18309.1 - 5.7e-60 202.8 0.3 6.9e-60 202.5 0.3 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KKK18309.1 - 4.8e-19 69.0 0.1 7.3e-19 68.4 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KKK18309.1 - 0.00049 19.2 0.1 0.00073 18.6 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.18 KKK18309.1 - 0.025 14.9 0.1 0.048 13.9 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain Sacchrp_dh_NADP PF03435.18 KKK18309.1 - 0.14 12.4 0.3 0.86 9.9 0.2 2.0 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Ribosomal_S14 PF00253.21 KKK18311.1 - 2.5e-21 75.2 0.5 7.5e-21 73.6 0.1 1.8 2 0 0 2 2 2 1 Ribosomal protein S14p/S29e DASH_Spc19 PF08287.11 KKK18312.1 - 1.3e-52 177.9 6.4 1.7e-52 177.5 6.4 1.2 1 0 0 1 1 1 1 Spc19 Mur_ligase_M PF08245.12 KKK18312.1 - 0.062 13.3 0.0 0.074 13.0 0.0 1.3 1 1 0 1 1 1 0 Mur ligase middle domain LPD30 PF18850.1 KKK18312.1 - 0.18 11.6 0.0 0.32 10.8 0.0 1.4 1 0 0 1 1 1 0 Large polyvalent protein associated domain 30 Rogdi_lz PF10259.9 KKK18313.1 - 3.3e-80 269.4 0.0 5e-80 268.8 0.0 1.2 1 0 0 1 1 1 1 Rogdi leucine zipper containing protein Rsm22 PF09243.10 KKK18313.1 - 2.1e-29 102.7 0.0 9.9e-29 100.5 0.0 2.0 1 1 0 1 1 1 1 Mitochondrial small ribosomal subunit Rsm22 SUR7 PF06687.12 KKK18314.1 - 1.6e-42 145.6 13.5 1.8e-42 145.4 13.5 1.0 1 0 0 1 1 1 1 SUR7/PalI family Clc-like PF07062.12 KKK18314.1 - 0.0092 15.5 3.0 0.015 14.8 3.0 1.4 1 0 0 1 1 1 1 Clc-like 30K_MP_C_Ter PF11330.8 KKK18314.1 - 0.22 10.8 0.1 0.38 10.1 0.0 1.4 2 0 0 2 2 2 0 C-Terminal of 30K viral movement proteins DUF373 PF04123.13 KKK18314.1 - 0.62 9.4 6.4 0.047 13.1 1.4 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF373) TIC20 PF16166.5 KKK18314.1 - 1.4 8.7 7.1 5.3 6.8 7.1 1.9 1 1 0 1 1 1 0 Chloroplast import apparatus Tic20-like Amastin PF07344.11 KKK18314.1 - 3.7 7.4 12.2 2.1 8.2 9.7 1.9 2 1 0 2 2 2 0 Amastin surface glycoprotein Vma12 PF11712.8 KKK18315.1 - 4.1e-41 140.3 0.0 6.4e-41 139.7 0.0 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase Amidohydro_1 PF01979.20 KKK18316.1 - 1.5e-26 93.5 0.0 4e-26 92.2 0.0 1.7 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KKK18316.1 - 4e-12 46.4 0.0 3.9e-07 29.9 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family Pyr_redox_2 PF07992.14 KKK18317.1 - 6e-72 242.3 6.6 6e-72 242.3 6.6 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 KKK18317.1 - 1.1e-40 138.2 0.2 3.5e-40 136.7 0.2 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 KKK18317.1 - 8.6e-22 77.5 9.0 1.4e-20 73.6 0.7 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KKK18317.1 - 8.6e-11 41.9 4.5 3.7e-06 27.1 0.5 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 KKK18317.1 - 5.4e-10 39.2 12.1 1e-09 38.3 0.4 3.0 2 1 1 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KKK18317.1 - 1.1e-09 38.0 4.9 1.4e-07 31.1 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KKK18317.1 - 4e-09 36.0 14.0 9.3e-08 31.5 4.3 3.2 2 2 1 3 3 3 2 Glucose inhibited division protein A DAO PF01266.24 KKK18317.1 - 1.2e-07 31.7 13.0 0.0083 15.8 0.5 4.2 4 0 0 4 4 4 3 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 KKK18317.1 - 2.7e-07 30.1 8.3 0.00072 18.9 0.7 3.6 3 1 0 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 KKK18317.1 - 4.3e-07 29.4 2.0 4.3e-07 29.4 2.0 2.6 2 1 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 KKK18317.1 - 5.8e-06 25.3 14.6 0.00039 19.2 1.5 4.1 4 0 0 4 4 4 2 HI0933-like protein K_oxygenase PF13434.6 KKK18317.1 - 5.9e-06 25.7 1.1 0.073 12.2 0.0 2.9 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 KKK18317.1 - 1.9e-05 24.0 3.7 0.00045 19.5 0.1 2.4 2 0 0 2 2 2 1 Thi4 family Lycopene_cycl PF05834.12 KKK18317.1 - 0.00098 18.3 1.8 0.15 11.1 0.0 2.7 2 1 0 2 2 2 2 Lycopene cyclase protein THF_DHG_CYH_C PF02882.19 KKK18317.1 - 0.002 17.5 1.1 0.19 11.0 0.0 3.9 3 2 1 4 4 4 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain FAD_binding_3 PF01494.19 KKK18317.1 - 0.0058 15.9 10.3 0.31 10.2 0.6 3.0 2 1 0 2 2 2 2 FAD binding domain 3HCDH_N PF02737.18 KKK18317.1 - 0.024 14.5 4.5 0.032 14.1 1.3 2.5 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 KKK18317.1 - 0.12 12.9 3.7 0.16 12.4 0.1 2.8 4 0 0 4 4 3 0 Putative NAD(P)-binding FMO-like PF00743.19 KKK18317.1 - 0.12 10.8 2.8 3.3 6.0 0.7 2.8 3 0 0 3 3 3 0 Flavin-binding monooxygenase-like Trp_halogenase PF04820.14 KKK18317.1 - 0.13 11.1 5.6 0.32 9.8 0.5 2.3 2 0 0 2 2 2 0 Tryptophan halogenase UDPG_MGDP_dh_N PF03721.14 KKK18317.1 - 6.4 6.3 7.1 1.8 8.1 0.5 2.8 3 0 0 3 3 3 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain PGM_PMM_I PF02878.16 KKK18318.1 - 1.7e-31 108.8 0.0 3.5e-31 107.8 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 KKK18318.1 - 6.9e-24 84.5 0.0 2.1e-23 82.9 0.0 1.9 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 KKK18318.1 - 3.5e-15 56.2 0.0 7.3e-15 55.2 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.20 KKK18318.1 - 2.2e-06 27.8 0.0 6.7e-06 26.2 0.0 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain HTH_20 PF12840.7 KKK18318.1 - 0.081 13.0 0.0 0.24 11.5 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain SecE PF00584.20 KKK18319.1 - 6.9e-13 48.3 0.0 8.3e-13 48.1 0.0 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex Sugar_tr PF00083.24 KKK18320.1 - 8.6e-88 295.2 22.0 1e-87 294.9 22.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKK18320.1 - 4.2e-21 75.3 47.7 3.6e-16 59.0 20.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KKK18320.1 - 0.54 8.5 15.6 0.26 9.5 2.0 3.4 1 1 2 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family DUF3100 PF11299.8 KKK18320.1 - 1.8 7.9 8.2 1.6 8.1 0.8 3.1 2 1 0 3 3 3 0 Protein of unknown function (DUF3100) zf-C2H2 PF00096.26 KKK18321.1 - 8.8e-10 38.5 7.3 1.9e-07 31.1 0.3 3.1 2 1 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KKK18321.1 - 0.00013 22.5 7.6 0.00018 22.0 0.2 3.1 3 0 0 3 3 3 1 C2H2-type zinc finger zf-met PF12874.7 KKK18321.1 - 0.02 15.3 0.0 0.11 12.9 0.0 2.2 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 KKK18321.1 - 0.023 14.4 0.0 0.058 13.2 0.0 1.6 1 0 0 1 1 1 0 zinc-finger C2H2-type zf-H2C2_2 PF13465.6 KKK18321.1 - 0.042 14.3 0.8 0.042 14.3 0.8 3.4 3 0 0 3 3 3 0 Zinc-finger double domain Methyltransf_13 PF08421.11 KKK18321.1 - 0.13 12.5 0.4 0.31 11.3 0.4 1.7 1 1 0 1 1 1 0 Putative zinc binding domain zf-LYAR PF08790.11 KKK18321.1 - 0.14 12.1 0.2 0.25 11.3 0.2 1.4 1 0 0 1 1 1 0 LYAR-type C2HC zinc finger DNA_binding_1 PF01035.20 KKK18322.1 - 1.3e-26 92.5 0.0 2.5e-26 91.6 0.0 1.5 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain DUF1770 PF08589.10 KKK18322.1 - 0.61 11.1 3.8 1 10.4 3.8 1.3 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF1770) FA_desaturase PF00487.24 KKK18324.1 - 1.3e-26 94.0 30.7 1.9e-26 93.5 30.7 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 KKK18324.1 - 5e-10 39.4 0.0 1.1e-09 38.3 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Ribosomal_S10 PF00338.22 KKK18325.1 - 3.6e-25 88.0 0.2 4.3e-25 87.8 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e CUE PF02845.16 KKK18326.1 - 4.4e-06 26.3 0.0 1.2e-05 24.9 0.0 1.8 1 0 0 1 1 1 1 CUE domain SMC_N PF02463.19 KKK18327.1 - 3e-79 265.5 0.0 5.8e-79 264.6 0.0 1.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KKK18327.1 - 1.6e-23 83.2 0.1 8e-23 81.0 0.0 2.3 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 KKK18327.1 - 5e-14 52.8 4.5 3.2e-06 27.2 0.0 4.0 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KKK18327.1 - 8.1e-05 22.3 0.0 0.00023 20.8 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain Spc7 PF08317.11 KKK18327.1 - 0.0041 16.1 12.3 0.0041 16.1 12.3 7.2 2 2 4 7 7 7 3 Spc7 kinetochore protein KASH_CCD PF14662.6 KKK18327.1 - 0.0043 16.9 21.9 0.0043 16.9 21.9 6.1 2 2 3 6 6 6 1 Coiled-coil region of CCDC155 or KASH Snapin_Pallidin PF14712.6 KKK18327.1 - 0.011 16.2 0.5 0.011 16.2 0.5 7.0 5 2 1 6 6 6 0 Snapin/Pallidin SbcCD_C PF13558.6 KKK18327.1 - 0.059 13.6 0.0 0.71 10.2 0.0 2.7 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit TMF_DNA_bd PF12329.8 KKK18327.1 - 0.19 11.7 0.0 0.19 11.7 0.0 10.8 7 3 5 12 12 12 0 TATA element modulatory factor 1 DNA binding ELYS PF13934.6 KKK18328.1 - 2.9e-66 223.6 1.1 4e-66 223.2 1.1 1.2 1 0 0 1 1 1 1 Nuclear pore complex assembly DUF1657 PF07870.11 KKK18328.1 - 0.04 13.8 0.1 0.084 12.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1657) CLP1_P PF16575.5 KKK18329.1 - 5.7e-28 98.0 0.0 1.1e-27 97.1 0.0 1.5 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_33 PF13671.6 KKK18329.1 - 0.057 13.6 0.0 0.24 11.6 0.0 2.2 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KKK18329.1 - 0.074 13.6 0.0 0.24 12.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KKK18329.1 - 0.13 12.7 0.0 0.71 10.3 0.0 2.2 3 0 0 3 3 3 0 RNA helicase FtsK_SpoIIIE PF01580.18 KKK18329.1 - 0.13 11.6 0.0 0.42 9.9 0.0 1.8 2 0 0 2 2 2 0 FtsK/SpoIIIE family Folliculin PF11704.8 KKK18330.1 - 3.1e-48 164.1 0.0 4.5e-48 163.6 0.0 1.2 1 0 0 1 1 1 1 Vesicle coat protein involved in Golgi to plasma membrane transport Prefoldin PF02996.17 KKK18331.1 - 1.6e-29 102.3 0.2 2.8e-29 101.5 0.2 1.4 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.20 KKK18331.1 - 0.0015 18.4 0.3 0.0058 16.6 0.1 2.1 1 1 0 1 1 1 1 Prefoldin subunit FlaC_arch PF05377.11 KKK18331.1 - 0.079 13.4 0.4 4.8 7.6 0.0 2.6 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) RNA_polI_A34 PF08208.11 KKK18332.1 - 5e-42 144.3 12.8 5e-42 144.3 12.8 3.5 3 0 0 3 3 3 1 DNA-directed RNA polymerase I subunit RPA34.5 GRAM PF02893.20 KKK18332.1 - 7.3e-35 119.3 3.3 5.3e-23 81.1 0.0 3.4 3 0 0 3 3 3 3 GRAM domain Glyco_transf_28 PF03033.20 KKK18332.1 - 1.5e-25 89.8 0.0 3e-25 88.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain PH PF00169.29 KKK18332.1 - 2.9e-15 56.7 0.6 2.4e-13 50.5 0.1 3.3 2 1 1 3 3 3 1 PH domain PH_3 PF14593.6 KKK18332.1 - 7.3e-05 22.8 0.0 0.00016 21.7 0.0 1.5 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 KKK18332.1 - 7.8e-05 23.0 0.6 0.00056 20.3 0.6 2.6 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 KKK18332.1 - 0.00011 22.4 0.1 0.00034 20.8 0.1 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain UDPGT PF00201.18 KKK18332.1 - 0.015 14.1 0.0 0.03 13.1 0.0 1.4 1 0 0 1 1 1 0 UDP-glucoronosyl and UDP-glucosyl transferase PH_2 PF08458.10 KKK18332.1 - 0.016 15.6 0.0 0.036 14.4 0.0 1.5 1 0 0 1 1 1 0 Plant pleckstrin homology-like region zf-C2H2 PF00096.26 KKK18352.1 - 4.9e-05 23.6 10.3 0.067 13.7 1.5 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_aberr PF17017.5 KKK18352.1 - 7.8e-05 22.9 1.0 0.046 13.9 0.0 2.3 2 0 0 2 2 2 2 Aberrant zinc-finger zf-C2H2_4 PF13894.6 KKK18352.1 - 0.00024 21.7 11.8 0.029 15.2 1.1 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KKK18352.1 - 0.017 15.4 1.1 1.1 9.6 0.1 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 KKK18352.1 - 0.019 15.4 0.5 0.019 15.4 0.5 3.2 3 0 0 3 3 3 0 Zinc-finger double domain DUF4719 PF15843.5 KKK18352.1 - 0.45 10.6 0.0 0.45 10.6 0.0 3.4 1 1 2 4 4 4 0 Domain of unknown function (DUF4719) HNF-1_N PF04814.13 KKK18352.1 - 2.3 8.8 9.6 0.23 12.1 2.9 2.5 3 0 0 3 3 3 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus Dus PF01207.17 KKK18353.1 - 4e-44 151.0 0.0 9.6e-32 110.3 0.0 2.7 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) zf_CCCH_4 PF18345.1 KKK18353.1 - 0.00036 20.5 6.1 0.12 12.5 0.5 2.5 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_4 PF18044.1 KKK18353.1 - 0.004 16.9 4.6 0.14 12.0 0.3 2.6 2 0 0 2 2 2 2 CCCH-type zinc finger zf-CCCH PF00642.24 KKK18353.1 - 0.29 11.1 3.2 7.5 6.6 0.4 2.7 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Bap31 PF05529.12 KKK18354.1 - 8.5e-46 155.2 7.4 1.3e-45 154.6 7.4 1.3 1 0 0 1 1 1 1 Bap31/Bap29 transmembrane region Bap31_Bap29_C PF18035.1 KKK18354.1 - 6.7e-16 58.0 1.5 1.2e-15 57.2 1.5 1.5 1 0 0 1 1 1 1 Bap31/Bap29 cytoplasmic coiled-coil domain DivIC PF04977.15 KKK18354.1 - 0.041 13.6 4.7 1 9.2 0.0 3.2 4 0 0 4 4 4 0 Septum formation initiator Nup54_57_C PF18570.1 KKK18354.1 - 0.24 11.0 1.2 6.7 6.4 0.0 2.4 1 1 1 2 2 2 0 NUP57/Nup54 C-terminal domain CAMSAP_CC1 PF17095.5 KKK18354.1 - 0.83 9.5 5.8 1.1 9.2 1.1 2.3 1 1 1 2 2 2 0 Spectrin-binding region of Ca2+-Calmodulin OpuAC PF04069.12 KKK18364.1 - 0.074 12.6 0.1 0.15 11.6 0.1 1.4 1 0 0 1 1 1 0 Substrate binding domain of ABC-type glycine betaine transport system Ribosomal_L22e PF01776.17 KKK18365.1 - 3.1e-47 159.5 0.4 3.9e-47 159.1 0.4 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family AlgF PF11182.8 KKK18365.1 - 0.034 13.9 0.0 0.069 12.9 0.0 1.5 2 0 0 2 2 2 0 Alginate O-acetyl transferase AlgF Meth_synt_2 PF01717.18 KKK18366.1 - 4.5e-17 62.3 0.0 2.2e-16 60.0 0.0 1.9 1 1 0 1 1 1 1 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 KKK18366.1 - 0.022 14.3 0.0 0.049 13.1 0.0 1.6 2 0 0 2 2 2 0 Cobalamin-independent synthase, N-terminal domain Arf PF00025.21 KKK18367.1 - 2.7e-71 238.6 0.2 3e-71 238.4 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KKK18367.1 - 6.7e-16 58.6 0.1 9e-16 58.2 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 KKK18367.1 - 2.7e-13 49.8 1.6 3.6e-09 36.2 0.4 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 KKK18367.1 - 6.1e-13 48.7 0.0 6.8e-13 48.5 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 KKK18367.1 - 3.4e-10 39.6 0.0 4.2e-10 39.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 KKK18367.1 - 1.1e-09 38.0 0.0 1.2e-09 37.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KKK18367.1 - 2.1e-05 24.6 0.0 2.9e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KKK18367.1 - 0.014 15.0 0.8 0.025 14.1 0.4 1.6 1 1 0 1 1 1 0 Ferrous iron transport protein B 6PF2K PF01591.18 KKK18367.1 - 0.018 14.4 0.3 0.039 13.3 0.1 1.6 2 0 0 2 2 2 0 6-phosphofructo-2-kinase DUF2722 PF10846.8 KKK18369.1 - 1.8e-06 27.2 0.0 1.8e-06 27.2 0.0 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF2722) RabGAP-TBC PF00566.18 KKK18370.1 - 0.36 10.5 0.0 0.36 10.5 0.0 1.7 2 0 0 2 2 2 0 Rab-GTPase-TBC domain RabGAP-TBC PF00566.18 KKK18371.1 - 2.4e-08 33.9 0.0 3.2e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Methyltransf_25 PF13649.6 KKK18372.1 - 2.7e-10 40.8 0.0 6.9e-10 39.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KKK18372.1 - 6.2e-09 36.4 0.0 1.4e-08 35.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KKK18372.1 - 2.5e-08 33.7 0.1 5.2e-08 32.6 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 KKK18372.1 - 3e-08 33.6 0.0 5.6e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 KKK18372.1 - 4.4e-05 23.5 0.1 8.8e-05 22.5 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KKK18372.1 - 9.1e-05 22.4 0.0 0.00017 21.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KKK18372.1 - 0.00015 21.4 0.1 0.00027 20.5 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_9 PF08003.11 KKK18372.1 - 0.0018 17.2 0.0 0.0038 16.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) TehB PF03848.14 KKK18372.1 - 0.0075 15.7 0.0 0.014 14.9 0.0 1.4 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_12 PF08242.12 KKK18372.1 - 0.023 15.5 0.0 0.07 13.9 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain CMAS PF02353.20 KKK18372.1 - 0.024 14.0 0.0 0.045 13.0 0.0 1.4 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase PCMT PF01135.19 KKK18372.1 - 0.026 14.3 0.0 0.045 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.18 KKK18372.1 - 0.055 12.8 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_24 PF13578.6 KKK18372.1 - 0.069 14.2 0.0 0.16 13.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain PRMT5 PF05185.16 KKK18372.1 - 0.089 12.6 0.8 0.86 9.4 0.8 2.1 1 1 0 1 1 1 0 PRMT5 arginine-N-methyltransferase Met_10 PF02475.16 KKK18372.1 - 0.1 12.3 0.1 0.2 11.4 0.1 1.4 1 0 0 1 1 1 0 Met-10+ like-protein DUF5636 PF18686.1 KKK18372.1 - 0.12 12.6 3.6 0.17 12.0 0.1 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5636) Mo25 PF08569.11 KKK18373.1 - 4.2e-134 447.0 0.0 4.8e-134 446.8 0.0 1.0 1 0 0 1 1 1 1 Mo25-like DLIC PF05783.11 KKK18373.1 - 0.076 11.8 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) AAA PF00004.29 KKK18374.1 - 4.7e-55 185.6 0.1 7e-38 130.0 0.0 2.9 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) CDC48_2 PF02933.17 KKK18374.1 - 1.5e-10 40.7 0.3 2.9e-09 36.6 0.0 2.7 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 AAA_22 PF13401.6 KKK18374.1 - 1.7e-09 38.0 0.2 0.00025 21.3 0.0 4.2 2 2 0 2 2 2 2 AAA domain AAA_lid_3 PF17862.1 KKK18374.1 - 8.1e-09 35.1 0.0 2e-08 33.9 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 KKK18374.1 - 1.5e-08 35.2 0.0 0.0038 17.6 0.0 3.5 2 1 0 3 3 3 2 AAA ATPase domain CDC48_N PF02359.18 KKK18374.1 - 3.8e-08 33.4 0.0 1.2e-07 31.8 0.0 1.8 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_2 PF07724.14 KKK18374.1 - 2e-07 31.3 0.2 4.3e-05 23.7 0.0 2.9 3 0 0 3 3 2 1 AAA domain (Cdc48 subfamily) AAA_18 PF13238.6 KKK18374.1 - 2.8e-07 31.1 0.0 0.02 15.5 0.0 3.8 4 0 0 4 4 3 2 AAA domain AAA_24 PF13479.6 KKK18374.1 - 6.3e-07 29.3 0.0 0.018 14.8 0.0 2.7 2 1 0 2 2 2 2 AAA domain ATPase_2 PF01637.18 KKK18374.1 - 8.7e-07 29.1 1.2 0.56 10.1 0.1 4.1 3 1 1 4 4 4 2 ATPase domain predominantly from Archaea Mg_chelatase PF01078.21 KKK18374.1 - 1.1e-06 28.2 0.0 0.0053 16.2 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 KKK18374.1 - 1.2e-06 28.4 0.0 0.033 13.9 0.0 2.7 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KKK18374.1 - 1.4e-06 28.3 0.0 0.0016 18.4 0.0 2.9 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 KKK18374.1 - 5.6e-06 26.6 0.0 0.11 12.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.13 KKK18374.1 - 7.7e-06 25.3 0.2 0.029 13.6 0.0 2.6 3 0 0 3 3 3 2 TIP49 P-loop domain RNA_helicase PF00910.22 KKK18374.1 - 4.2e-05 23.9 0.0 0.11 12.9 0.0 2.8 2 0 0 2 2 2 2 RNA helicase AAA_14 PF13173.6 KKK18374.1 - 8.3e-05 22.6 0.0 0.19 11.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 KKK18374.1 - 0.00031 20.3 0.4 0.02 14.4 0.0 2.8 3 0 0 3 3 3 1 P-loop containing dynein motor region TniB PF05621.11 KKK18374.1 - 0.00033 20.1 0.2 1.8 7.9 0.0 3.8 3 1 0 3 3 3 1 Bacterial TniB protein ATPase PF06745.13 KKK18374.1 - 0.0004 19.8 1.3 0.035 13.5 0.2 3.0 2 1 1 3 3 3 1 KaiC AAA_25 PF13481.6 KKK18374.1 - 0.00044 19.9 0.5 1.3 8.5 0.0 3.1 2 2 2 4 4 4 2 AAA domain IstB_IS21 PF01695.17 KKK18374.1 - 0.00062 19.6 0.0 0.1 12.3 0.0 2.7 2 0 0 2 2 2 1 IstB-like ATP binding protein TsaE PF02367.17 KKK18374.1 - 0.0025 17.8 0.0 0.39 10.7 0.0 2.7 2 1 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 KKK18374.1 - 0.003 17.8 0.0 1.3 9.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 KKK18374.1 - 0.0034 17.9 0.2 0.016 15.7 0.1 2.1 2 0 0 2 2 1 1 ABC transporter Parvo_NS1 PF01057.17 KKK18374.1 - 0.0043 16.2 0.1 0.48 9.5 0.0 2.3 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 Sigma54_activat PF00158.26 KKK18374.1 - 0.011 15.5 0.1 0.65 9.7 0.0 2.8 3 0 0 3 3 2 0 Sigma-54 interaction domain AAA_17 PF13207.6 KKK18374.1 - 0.018 15.5 0.0 6.4 7.2 0.0 2.8 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 KKK18374.1 - 0.018 14.5 1.0 2.1 7.8 0.0 2.7 3 0 0 3 3 2 0 PhoH-like protein AAA_19 PF13245.6 KKK18374.1 - 0.03 14.7 0.4 0.67 10.3 0.0 2.9 2 1 1 3 3 3 0 AAA domain NB-ARC PF00931.22 KKK18374.1 - 0.032 13.4 0.0 1.9 7.6 0.1 2.6 2 1 1 3 3 3 0 NB-ARC domain IPT PF01745.16 KKK18374.1 - 0.032 13.6 0.0 0.67 9.3 0.0 2.7 2 1 1 3 3 3 0 Isopentenyl transferase NACHT PF05729.12 KKK18374.1 - 0.037 14.0 0.0 5.5 6.9 0.0 3.0 3 1 0 3 3 2 0 NACHT domain AAA_3 PF07726.11 KKK18374.1 - 0.037 13.9 0.0 0.44 10.4 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) KTI12 PF08433.10 KKK18374.1 - 0.046 13.2 0.0 4 6.8 0.0 2.4 2 0 0 2 2 2 0 Chromatin associated protein KTI12 AAA_11 PF13086.6 KKK18374.1 - 0.055 13.2 0.1 0.71 9.6 0.0 2.4 2 1 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.25 KKK18374.1 - 0.17 11.5 0.0 2.1 8.0 0.0 2.7 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Cir_N PF10197.9 KKK18375.1 - 1.6e-07 31.4 8.4 1.6e-07 31.4 8.4 3.6 4 0 0 4 4 4 1 N-terminal domain of CBF1 interacting co-repressor CIR DIL PF01843.19 KKK18376.1 - 3.5e-31 107.6 0.7 7.8e-31 106.4 0.7 1.6 1 0 0 1 1 1 1 DIL domain Ank_2 PF12796.7 KKK18376.1 - 3.2e-14 53.3 0.0 1e-13 51.7 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KKK18376.1 - 2.5e-11 43.6 0.0 1.2e-06 28.7 0.0 2.9 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 KKK18376.1 - 9.1e-11 42.1 0.1 5.9e-05 23.5 0.1 4.1 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 KKK18376.1 - 1.4e-08 34.8 0.0 0.009 16.4 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 KKK18376.1 - 5.8e-06 26.3 0.7 0.0095 16.4 0.0 3.8 4 0 0 4 4 4 1 Ankyrin repeat RasGEF PF00617.19 KKK18377.1 - 3.7e-40 138.0 0.0 1.2e-39 136.4 0.0 1.8 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 KKK18377.1 - 3.9e-12 46.3 0.1 1e-11 45.0 0.1 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif KxDL PF10241.9 KKK18378.1 - 1.8e-32 111.4 0.5 2.4e-32 111.1 0.5 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein DUF4407 PF14362.6 KKK18378.1 - 0.046 13.1 1.5 0.055 12.8 1.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Response_reg PF00072.24 KKK18379.1 - 9.6e-22 77.3 0.1 1.8e-21 76.4 0.1 1.5 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 KKK18379.1 - 1e-21 77.5 0.4 3.2e-21 75.9 0.0 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 KKK18379.1 - 1.7e-16 60.0 0.1 5.2e-16 58.4 0.1 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_3 PF08447.12 KKK18379.1 - 1.2e-10 41.5 2.2 0.00071 19.8 0.2 3.9 3 0 0 3 3 3 3 PAS fold PAS_4 PF08448.10 KKK18379.1 - 3.8e-06 27.1 0.1 1.6e-05 25.1 0.1 2.1 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.7 KKK18379.1 - 0.00071 19.8 0.0 0.28 11.5 0.0 3.7 3 1 0 3 3 3 1 PAS domain PAS PF00989.25 KKK18379.1 - 0.0083 16.1 0.0 0.77 9.8 0.0 2.8 2 0 0 2 2 2 1 PAS fold MotA_ExbB PF01618.16 KKK18379.1 - 0.081 12.7 0.0 0.2 11.4 0.0 1.6 1 0 0 1 1 1 0 MotA/TolQ/ExbB proton channel family DUF3256 PF11644.8 KKK18379.1 - 0.12 11.9 0.2 0.26 10.8 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3256) G-alpha PF00503.20 KKK18380.1 - 2.5e-106 355.8 0.2 3e-106 355.6 0.2 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KKK18380.1 - 5.3e-14 52.1 0.5 2.3e-09 36.9 0.0 2.8 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KKK18380.1 - 1.2e-07 31.4 0.1 0.0009 18.7 0.1 2.2 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 KKK18380.1 - 0.0048 17.1 0.0 1.1 9.5 0.0 2.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 KKK18380.1 - 0.005 16.9 0.0 3.5 7.7 0.0 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase TniB PF05621.11 KKK18380.1 - 0.026 14.0 0.0 0.05 13.0 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein AAA_29 PF13555.6 KKK18380.1 - 0.078 12.7 0.1 0.16 11.7 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.6 KKK18380.1 - 0.17 11.5 0.0 0.34 10.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain Peptidase_M13_N PF05649.13 KKK18381.1 - 1.5e-93 314.5 0.0 1.9e-93 314.2 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 KKK18381.1 - 2.5e-48 164.4 0.7 6e-34 117.5 0.0 2.3 1 1 1 2 2 2 2 Peptidase family M13 DUF3149 PF11346.8 KKK18381.1 - 0.019 14.6 0.0 0.034 13.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3149) ATP-synt_C PF00137.21 KKK18382.1 - 4.7e-36 122.9 34.6 4.6e-22 78.1 15.3 2.1 2 0 0 2 2 2 2 ATP synthase subunit C DUF1713 PF08213.11 KKK18383.1 - 8.7e-11 41.6 20.6 1.6e-10 40.7 20.6 1.5 1 0 0 1 1 1 1 Mitochondrial domain of unknown function (DUF1713) Pet20 PF08692.10 KKK18383.1 - 0.0042 17.8 0.3 0.014 16.1 0.0 2.1 2 1 0 2 2 2 1 Mitochondrial protein Pet20 TMEM171 PF15471.6 KKK18383.1 - 3.8 6.4 5.6 1.1 8.2 2.0 1.8 1 1 1 2 2 2 0 Transmembrane protein family 171 Pmp3 PF01679.17 KKK18384.1 - 1.5e-24 85.9 9.0 1.6e-24 85.8 9.0 1.0 1 0 0 1 1 1 1 Proteolipid membrane potential modulator Hydrolase_6 PF13344.6 KKK18386.1 - 7.3e-22 77.4 0.0 1.4e-21 76.4 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KKK18386.1 - 1e-12 47.9 0.0 2.7e-11 43.4 0.0 3.0 4 0 0 4 4 4 1 HAD-hyrolase-like Hydrolase PF00702.26 KKK18386.1 - 0.15 12.3 0.0 17 5.6 0.0 2.8 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase CFEM PF05730.11 KKK18387.1 - 0.038 14.1 3.9 0.072 13.2 3.9 1.4 1 0 0 1 1 1 0 CFEM domain Asp PF00026.23 KKK18388.1 - 2.3e-08 33.9 0.9 3.9e-08 33.1 0.9 1.3 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Podoplanin PF05808.11 KKK18388.1 - 0.0099 16.0 0.0 0.019 15.1 0.0 1.4 1 0 0 1 1 1 1 Podoplanin SKG6 PF08693.10 KKK18388.1 - 0.018 14.5 2.6 0.053 12.9 2.6 1.8 1 0 0 1 1 1 0 Transmembrane alpha-helix domain VSP PF03302.13 KKK18388.1 - 0.038 12.8 0.4 0.038 12.8 0.4 1.9 2 0 0 2 2 2 0 Giardia variant-specific surface protein Vpu PF00558.19 KKK18388.1 - 0.13 12.1 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 Vpu protein DUF676 PF05057.14 KKK18389.1 - 7.5e-48 162.9 0.0 1.1e-47 162.4 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 KKK18389.1 - 1e-06 29.5 0.1 1.8e-06 28.8 0.1 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 KKK18389.1 - 0.00042 20.1 0.0 0.00091 19.0 0.0 1.5 1 1 0 1 1 1 1 PGAP1-like protein Palm_thioest PF02089.15 KKK18389.1 - 0.0051 16.7 0.0 0.0085 16.0 0.0 1.3 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Lipase_3 PF01764.25 KKK18389.1 - 0.026 14.4 0.0 0.054 13.4 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) LCAT PF02450.15 KKK18389.1 - 0.026 13.7 0.0 0.042 13.0 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DUF915 PF06028.11 KKK18389.1 - 0.14 11.4 0.0 6.6 6.0 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) FA_hydroxylase PF04116.13 KKK18395.1 - 4e-25 88.7 16.9 4e-25 88.7 16.9 2.0 2 1 1 3 3 3 1 Fatty acid hydroxylase superfamily Ras PF00071.22 KKK18396.1 - 3.1e-65 218.7 0.1 3.6e-65 218.5 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KKK18396.1 - 4.9e-34 117.1 0.0 7.2e-34 116.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKK18396.1 - 8e-14 51.5 0.1 1e-13 51.1 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KKK18396.1 - 3.1e-06 26.9 0.0 7.8e-06 25.6 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KKK18396.1 - 0.00011 21.6 0.0 0.00013 21.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 KKK18396.1 - 0.00042 20.2 0.2 0.43 10.5 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 KKK18396.1 - 0.0049 16.9 0.0 0.007 16.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KKK18396.1 - 0.016 14.8 0.0 0.076 12.5 0.0 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B SRPRB PF09439.10 KKK18396.1 - 0.031 13.7 0.0 0.037 13.5 0.0 1.1 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA PF00004.29 KKK18396.1 - 0.049 14.1 0.0 8.2 6.9 0.0 2.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KKK18396.1 - 0.16 12.3 0.0 0.49 10.7 0.0 2.0 1 1 0 1 1 1 0 AAA domain NCA2 PF08637.10 KKK18397.1 - 1.6e-92 309.8 0.0 2.6e-92 309.1 0.0 1.3 1 0 0 1 1 1 1 ATP synthase regulation protein NCA2 RRM_1 PF00076.22 KKK18398.1 - 7.1e-15 54.6 0.0 1.1e-14 54.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KKK18398.1 - 0.023 14.8 0.0 0.04 14.0 0.0 1.3 1 0 0 1 1 1 0 RNA binding motif RRM_5 PF13893.6 KKK18398.1 - 0.07 12.7 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Corona_nucleoca PF00937.18 KKK18398.1 - 0.093 11.8 9.5 0.16 11.0 9.5 1.4 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein AAA PF00004.29 KKK18399.1 - 5.8e-62 208.0 0.0 1.3e-41 142.1 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KKK18399.1 - 1.1e-17 63.5 2.1 6.2e-12 45.1 1.6 3.2 2 1 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 KKK18399.1 - 3.5e-11 43.8 1.0 0.013 15.9 0.2 4.7 2 2 2 4 4 4 2 AAA ATPase domain AAA_5 PF07728.14 KKK18399.1 - 1.1e-06 28.7 1.3 0.0039 17.2 0.1 3.3 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) Rad17 PF03215.15 KKK18399.1 - 9.6e-06 25.6 0.0 0.00016 21.7 0.0 2.4 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_28 PF13521.6 KKK18399.1 - 2.5e-05 24.6 0.0 0.18 12.1 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 KKK18399.1 - 2.5e-05 23.9 0.1 0.24 10.9 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region Bac_DnaA PF00308.18 KKK18399.1 - 4.1e-05 23.5 0.0 0.0012 18.8 0.0 2.5 2 1 0 2 2 2 1 Bacterial dnaA protein AAA_22 PF13401.6 KKK18399.1 - 4.7e-05 23.7 4.0 1.3 9.3 0.1 4.8 3 2 1 5 5 4 2 AAA domain RuvB_N PF05496.12 KKK18399.1 - 0.00011 21.9 0.0 0.016 14.9 0.0 3.4 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 KKK18399.1 - 0.00013 22.3 0.0 0.51 10.8 0.0 2.8 2 1 0 2 2 2 2 RNA helicase TIP49 PF06068.13 KKK18399.1 - 0.00017 20.9 0.0 0.011 15.0 0.0 2.5 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_2 PF07724.14 KKK18399.1 - 0.00077 19.6 0.0 0.003 17.7 0.0 2.0 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_14 PF13173.6 KKK18399.1 - 0.00093 19.2 0.0 0.64 10.0 0.0 3.1 3 0 0 3 3 3 1 AAA domain ATPase_2 PF01637.18 KKK18399.1 - 0.0015 18.5 0.2 0.5 10.2 0.0 3.3 2 1 1 3 3 3 1 ATPase domain predominantly from Archaea DUF815 PF05673.13 KKK18399.1 - 0.0023 17.1 0.0 1.9 7.6 0.0 2.6 3 0 0 3 3 3 2 Protein of unknown function (DUF815) IstB_IS21 PF01695.17 KKK18399.1 - 0.0033 17.2 0.0 2.7 7.7 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein Vps4_C PF09336.10 KKK18399.1 - 0.0061 16.5 0.1 0.29 11.2 0.0 2.8 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_24 PF13479.6 KKK18399.1 - 0.013 15.2 0.0 1.1 8.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.6 KKK18399.1 - 0.014 15.2 0.0 1.6 8.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 KKK18399.1 - 0.014 14.9 1.9 29 4.2 0.0 3.9 3 1 0 3 3 3 0 AAA domain AAA_29 PF13555.6 KKK18399.1 - 0.049 13.4 0.1 0.19 11.5 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_30 PF13604.6 KKK18399.1 - 0.058 13.1 0.1 2.4 7.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 KKK18399.1 - 0.12 11.7 0.5 2.7 7.3 0.0 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI TsaE PF02367.17 KKK18399.1 - 0.15 12.1 0.1 14 5.7 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Adeno_IVa2 PF02456.15 KKK18399.1 - 0.16 10.8 0.2 6.6 5.4 0.0 2.2 2 0 0 2 2 2 0 Adenovirus IVa2 protein TniB PF05621.11 KKK18399.1 - 0.16 11.4 0.0 20 4.5 0.0 3.0 2 1 1 3 3 3 0 Bacterial TniB protein NACHT PF05729.12 KKK18399.1 - 0.24 11.3 1.0 9.3 6.1 0.2 3.5 2 2 1 3 3 3 0 NACHT domain Swi3 PF07962.12 KKK18400.1 - 1.4e-33 114.7 0.4 3e-33 113.6 0.4 1.6 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 NADH-u_ox-rdase PF10785.9 KKK18401.1 - 3.9e-26 91.5 0.1 1.2e-25 89.9 0.1 1.9 1 1 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit NADH_u_ox_C PF12853.7 KKK18401.1 - 2e-25 88.6 0.1 2.7e-25 88.1 0.1 1.2 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit dCMP_cyt_deam_1 PF00383.23 KKK18402.1 - 1.7e-25 88.8 0.0 2.2e-25 88.4 0.0 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KKK18402.1 - 4.8e-21 75.0 0.0 7e-21 74.4 0.0 1.1 1 0 0 1 1 1 1 MafB19-like deaminase XOO_2897-deam PF14440.6 KKK18402.1 - 0.0011 19.0 0.0 0.0022 18.1 0.0 1.5 1 0 0 1 1 1 1 Xanthomonas XOO_2897-like deaminase APOBEC4_like PF18774.1 KKK18402.1 - 0.0027 17.7 0.0 0.0043 17.0 0.0 1.3 1 0 0 1 1 1 1 APOBEC4-like -AID/APOBEC-deaminase SNAD4 PF18750.1 KKK18402.1 - 0.009 16.1 0.0 0.016 15.3 0.0 1.4 1 0 0 1 1 1 1 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC3 PF18771.1 KKK18402.1 - 0.03 14.4 0.0 0.047 13.8 0.0 1.3 1 0 0 1 1 1 0 APOBEC3 APOBEC2 PF18772.1 KKK18402.1 - 0.049 13.7 0.0 0.064 13.3 0.0 1.2 1 0 0 1 1 1 0 APOBEC2 NAD1 PF18778.1 KKK18402.1 - 0.052 13.6 0.0 0.071 13.2 0.0 1.2 1 0 0 1 1 1 0 Novel AID APOBEC clade 1 APOBEC_N PF08210.11 KKK18402.1 - 0.053 13.4 0.0 0.079 12.8 0.0 1.2 1 0 0 1 1 1 0 APOBEC-like N-terminal domain Bd3614-deam PF14439.6 KKK18402.1 - 0.12 12.4 0.9 0.51 10.4 0.9 1.9 1 1 0 1 1 1 0 Bd3614-like deaminase PI3_PI4_kinase PF00454.27 KKK18403.1 - 1.8e-55 188.5 0.0 3.7e-55 187.5 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 KKK18403.1 - 5.5e-45 154.1 2.5 1.1e-44 153.1 2.5 1.6 1 0 0 1 1 1 1 FAT domain UME PF08064.13 KKK18403.1 - 8.3e-28 96.3 0.2 4.9e-27 93.8 0.2 2.4 1 0 0 1 1 1 1 UME (NUC010) domain FATC PF02260.20 KKK18403.1 - 1.3e-12 47.3 0.0 3.4e-12 46.0 0.0 1.8 1 0 0 1 1 1 1 FATC domain TPR_7 PF13176.6 KKK18403.1 - 0.015 15.3 0.6 13 6.0 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF3385 PF11865.8 KKK18403.1 - 0.058 13.3 0.1 0.3 11.0 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3385) TPR_19 PF14559.6 KKK18403.1 - 0.076 13.5 0.5 12 6.6 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat BTAD PF03704.17 KKK18403.1 - 0.11 13.0 4.3 0.51 10.8 0.0 3.2 3 0 0 3 3 3 0 Bacterial transcriptional activator domain MatP_C PF17414.2 KKK18403.1 - 0.22 11.7 1.9 0.92 9.7 0.2 3.0 3 0 0 3 3 3 0 MatP C-terminal ribbon-helix-helix domain TPR_14 PF13428.6 KKK18403.1 - 0.35 11.8 5.2 31 5.8 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat Metallophos_2 PF12850.7 KKK18413.1 - 2.1e-12 47.5 0.0 2.6e-12 47.2 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Aminotran_5 PF00266.19 KKK18414.1 - 5.6e-29 101.2 0.0 7.1e-29 100.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V B12-binding PF02310.19 KKK18414.1 - 0.024 14.6 0.0 0.073 13.1 0.0 1.8 1 0 0 1 1 1 0 B12 binding domain AIM5 PF17050.5 KKK18415.1 - 1.2e-14 54.9 1.9 1.6e-14 54.5 1.9 1.2 1 0 0 1 1 1 1 Altered inheritance of mitochondria 5 Rpn9_C PF18261.1 KKK18415.1 - 0.0076 15.8 0.4 0.018 14.6 0.4 1.6 1 0 0 1 1 1 1 Rpn9 C-terminal helix Ribosomal_L17 PF01196.19 KKK18416.1 - 2.7e-34 117.9 0.0 4.3e-34 117.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L17 Molybdopterin_N PF18364.1 KKK18416.1 - 0.16 12.0 0.1 0.44 10.6 0.0 1.8 2 0 0 2 2 2 0 Molybdopterin oxidoreductase N-terminal domain PIEZO PF15917.5 KKK18416.1 - 4.2 6.8 6.6 0.94 8.9 3.5 1.4 2 0 0 2 2 2 0 Piezo SUZ PF12752.7 KKK18417.1 - 1.1e-16 61.3 2.4 1.1e-16 61.3 2.4 2.9 2 0 0 2 2 2 1 SUZ domain R3H PF01424.22 KKK18417.1 - 1.3e-07 31.5 0.0 3e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 R3H domain zf-CCHC_3 PF13917.6 KKK18418.1 - 0.051 13.5 0.5 0.051 13.5 0.5 2.1 2 0 0 2 2 2 0 Zinc knuckle NIF PF03031.18 KKK18419.1 - 8.4e-59 197.8 0.0 1.3e-58 197.2 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Ndc1_Nup PF09531.10 KKK18419.1 - 1.7 7.3 5.0 2.1 6.9 5.0 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup IF-2B PF01008.17 KKK18420.1 - 1.1e-61 208.5 0.3 1.4e-59 201.6 0.3 2.3 1 1 0 1 1 1 1 Initiation factor 2 subunit family Ribosom_S12_S23 PF00164.25 KKK18421.1 - 3.5e-51 171.6 0.6 4.6e-51 171.2 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Methyltransf_15 PF09445.10 KKK18421.1 - 0.01 15.4 0.0 0.011 15.3 0.0 1.1 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Mononeg_mRNAcap PF14318.6 KKK18421.1 - 0.19 10.9 0.0 0.23 10.7 0.0 1.1 1 0 0 1 1 1 0 Mononegavirales mRNA-capping region V DUF5315 PF17242.2 KKK18422.1 - 1.1e-25 89.2 1.6 1.1e-25 89.2 1.6 1.7 2 0 0 2 2 2 1 Disordered region of unknown function (DUF5315) PPR_2 PF13041.6 KKK18423.1 - 1.3e-11 44.5 5.2 0.00032 20.8 0.0 4.6 4 1 1 5 5 5 3 PPR repeat family PPR_3 PF13812.6 KKK18423.1 - 9.4e-09 35.2 0.8 0.027 14.5 0.0 3.9 3 0 0 3 3 3 3 Pentatricopeptide repeat domain PPR PF01535.20 KKK18423.1 - 0.0038 17.4 0.3 1.2 9.6 0.0 3.9 4 0 0 4 4 4 1 PPR repeat DUF5617 PF18493.1 KKK18423.1 - 0.0071 16.4 1.5 0.017 15.2 0.7 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF5617) cwf18 PF08315.12 KKK18424.1 - 6.2e-45 153.2 7.3 1.1e-44 152.3 7.3 1.4 1 0 0 1 1 1 1 cwf18 pre-mRNA splicing factor KicB PF03882.14 KKK18424.1 - 0.059 13.6 0.1 0.11 12.7 0.1 1.5 1 0 0 1 1 1 0 MukF winged-helix domain PP2C PF00481.21 KKK18425.1 - 3e-76 256.5 0.0 4.3e-76 255.9 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C Roughex PF06020.11 KKK18425.1 - 0.057 12.5 5.9 0.087 11.9 5.9 1.2 1 0 0 1 1 1 0 Drosophila roughex protein CTP_transf_like PF01467.26 KKK18426.1 - 2.3e-29 102.4 0.0 4e-29 101.6 0.0 1.4 1 0 0 1 1 1 1 Cytidylyltransferase-like EamA PF00892.20 KKK18427.1 - 1.6e-16 60.7 25.1 2.2e-09 37.6 1.3 3.4 4 0 0 4 4 4 3 EamA-like transporter family VIR_N PF15912.5 KKK18427.1 - 0.016 14.8 0.0 0.037 13.6 0.0 1.5 1 0 0 1 1 1 0 Virilizer, N-terminal DUF4692 PF15763.5 KKK18427.1 - 0.1 13.0 0.4 0.21 12.1 0.4 1.4 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) Phage_holin_3_6 PF07332.11 KKK18427.1 - 3 7.9 0.0 3 7.9 0.0 3.7 3 1 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III IMUP PF15761.5 KKK18427.1 - 3.8 8.3 9.2 7.2 7.4 9.2 1.3 1 0 0 1 1 1 0 Immortalisation up-regulated protein UTP25 PF06862.12 KKK18428.1 - 4.3e-167 556.7 0.0 6.3e-99 331.9 0.0 2.1 1 1 1 2 2 2 2 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 MitMem_reg PF13012.6 KKK18429.1 - 3.8e-20 72.4 0.2 7.2e-20 71.5 0.2 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 KKK18429.1 - 2.1e-19 69.6 0.0 3.6e-19 68.9 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease UPF0172 PF03665.13 KKK18429.1 - 8.8e-05 22.6 0.0 0.00023 21.3 0.0 1.6 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0172) TFIID-18kDa PF02269.16 KKK18430.1 - 6.7e-23 80.5 0.0 1.5e-22 79.4 0.0 1.6 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit CENP-T_C PF15511.6 KKK18430.1 - 0.055 13.6 0.1 0.1 12.7 0.1 1.4 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 KKK18430.1 - 0.065 13.4 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) Histone PF00125.24 KKK18430.1 - 0.085 13.2 0.0 0.085 13.2 0.0 2.8 3 0 0 3 3 3 0 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 KKK18430.1 - 0.093 13.1 0.0 0.18 12.2 0.0 1.4 1 0 0 1 1 1 0 CENP-S protein Bromo_TP PF07524.13 KKK18430.1 - 0.1 12.6 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated HECT PF00632.25 KKK18431.1 - 2.2e-96 323.0 0.0 3.3e-96 322.4 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 KKK18431.1 - 2e-33 114.1 23.1 1.1e-11 44.6 4.0 4.0 4 0 0 4 4 4 3 WW domain C2 PF00168.30 KKK18431.1 - 2.4e-17 63.1 0.0 7e-17 61.6 0.0 1.8 1 0 0 1 1 1 1 C2 domain RRM_1 PF00076.22 KKK18431.1 - 2.6e-15 56.0 0.0 6.8e-15 54.6 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KKK18431.1 - 0.06 13.3 0.0 0.24 11.4 0.0 2.0 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif DUF724 PF05266.14 KKK18431.1 - 0.55 10.0 4.1 1 9.2 4.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Rrn6 PF10214.9 KKK18431.1 - 0.64 8.4 10.1 1.1 7.7 10.1 1.3 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Spc7 PF08317.11 KKK18431.1 - 2.6 6.8 8.1 4.4 6.1 8.1 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Aminotran_1_2 PF00155.21 KKK18433.1 - 1.8e-72 244.6 0.0 2e-72 244.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II TYW3 PF02676.14 KKK18435.1 - 1.5e-74 250.0 0.0 1.9e-74 249.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase TYW3 Ag332 PF04671.12 KKK18435.1 - 2.3 8.2 4.6 5.7 7.0 1.7 2.5 2 0 0 2 2 2 0 Erythrocyte membrane-associated giant protein antigen 332 DUF2461 PF09365.10 KKK18436.1 - 2.1e-78 263.1 0.0 2.9e-78 262.6 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein (DUF2461) Red1 PF07964.11 KKK18436.1 - 0.64 8.2 15.8 0.92 7.7 15.8 1.1 1 0 0 1 1 1 0 Rec10 / Red1 Presenilin PF01080.17 KKK18436.1 - 1.2 7.8 7.2 2.4 6.9 7.2 1.4 1 0 0 1 1 1 0 Presenilin Macoilin PF09726.9 KKK18436.1 - 5.5 5.4 7.7 7.4 5.0 7.7 1.2 1 0 0 1 1 1 0 Macoilin family Lyase_1 PF00206.20 KKK18437.1 - 2.3e-115 385.3 0.0 3.1e-115 384.9 0.0 1.2 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 KKK18437.1 - 9e-21 74.1 0.0 2.3e-20 72.7 0.0 1.8 1 0 0 1 1 1 1 Fumarase C C-terminus Abhydrolase_3 PF07859.13 KKK18438.1 - 3.5e-10 40.1 0.2 8.3e-05 22.5 0.0 2.0 1 1 1 2 2 2 2 alpha/beta hydrolase fold ARPC4 PF05856.12 KKK18439.1 - 6.5e-79 263.4 3.9 7.2e-79 263.2 3.9 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) UCH PF00443.29 KKK18440.1 - 1.7e-51 175.2 0.1 2.1e-51 174.9 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KKK18440.1 - 8.8e-12 45.2 8.1 9e-11 41.9 8.1 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 KKK18440.1 - 7e-11 41.7 0.1 2.1e-10 40.2 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin family 4HBT PF03061.22 KKK18441.1 - 0.0012 19.1 0.0 0.002 18.4 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily TRI12 PF06609.13 KKK18442.1 - 1.4e-37 129.5 25.0 1.7e-37 129.2 25.0 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 KKK18442.1 - 4.9e-16 58.6 56.2 4.9e-16 58.6 56.2 3.0 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KKK18442.1 - 1.1e-09 37.7 35.1 5.1e-09 35.5 10.5 2.8 2 1 1 3 3 3 2 Sugar (and other) transporter Cation_ATPase_C PF00689.21 KKK18442.1 - 0.0004 20.1 5.0 0.0004 20.1 5.0 2.5 2 1 0 2 2 2 1 Cation transporting ATPase, C-terminus Zn_ribbon_17 PF17120.5 KKK18443.1 - 1.8e-08 33.8 20.1 3.2e-05 23.5 10.4 2.9 2 0 0 2 2 2 2 Zinc-ribbon, C4HC2 type WD40 PF00400.32 KKK18443.1 - 9.6e-07 29.4 24.3 0.0033 18.2 0.1 6.9 6 0 0 6 6 6 3 WD domain, G-beta repeat RWD PF05773.22 KKK18443.1 - 0.0041 17.4 0.0 0.0088 16.3 0.0 1.5 1 0 0 1 1 1 1 RWD domain zf-RING_14 PF17978.1 KKK18443.1 - 4.6 7.7 9.3 11 6.6 9.3 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Ribosomal_L24e PF01246.20 KKK18444.1 - 3.1e-29 101.0 0.1 8.8e-29 99.5 0.1 1.8 1 0 0 1 1 1 1 Ribosomal protein L24e Ribosomal_S30 PF04758.14 KKK18445.1 - 6.4e-28 96.7 6.7 7e-28 96.6 6.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 Acetyltransf_1 PF00583.25 KKK18446.1 - 6e-11 42.6 0.1 7.7e-11 42.3 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KKK18446.1 - 6.3e-09 35.8 0.0 8.7e-09 35.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KKK18446.1 - 3e-07 30.8 0.3 4.5e-07 30.2 0.3 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Zn_clus PF00172.18 KKK18447.1 - 0.0033 17.5 7.7 0.007 16.5 7.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BRAP2 PF07576.12 KKK18448.1 - 3.3e-35 120.3 0.0 7.7e-35 119.1 0.0 1.5 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.19 KKK18448.1 - 5.5e-20 71.5 2.9 1.7e-19 69.9 2.9 1.9 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.6 KKK18448.1 - 4.6e-08 33.3 9.5 4.6e-08 33.3 9.5 2.5 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 KKK18448.1 - 1.5e-05 24.8 9.7 1.5e-05 24.8 9.7 2.1 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KKK18448.1 - 0.00068 19.9 7.1 0.00068 19.9 7.1 2.5 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 KKK18448.1 - 0.001 18.7 5.7 0.001 18.7 5.7 2.6 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4 PF00097.25 KKK18448.1 - 0.0012 18.7 8.8 0.0012 18.7 8.8 2.0 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KKK18448.1 - 0.0012 18.6 6.0 0.0012 18.6 6.0 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KKK18448.1 - 0.0017 18.3 6.3 0.0017 18.3 6.3 2.7 2 1 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 KKK18448.1 - 0.0022 17.9 7.9 0.0022 17.9 7.9 2.4 2 0 0 2 2 2 1 zinc-RING finger domain ZapB PF06005.12 KKK18448.1 - 0.007 16.8 4.2 0.0094 16.4 0.6 2.3 1 1 1 2 2 2 1 Cell division protein ZapB zf-RING_6 PF14835.6 KKK18448.1 - 0.0076 16.1 3.1 0.0076 16.1 3.1 2.0 2 0 0 2 2 1 1 zf-RING of BARD1-type protein Shugoshin_N PF07558.11 KKK18448.1 - 0.02 14.7 1.2 0.045 13.6 1.2 1.5 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region ALS2CR11 PF15729.5 KKK18448.1 - 0.037 13.2 0.9 0.086 12.0 0.9 1.6 1 1 0 1 1 1 0 Amyotrophic lateral sclerosis 2 candidate 11 AIP3 PF03915.13 KKK18448.1 - 0.06 12.4 4.3 0.096 11.8 4.3 1.2 1 0 0 1 1 1 0 Actin interacting protein 3 TPR_MLP1_2 PF07926.12 KKK18448.1 - 1.1 9.4 13.6 2.2 8.4 13.6 1.5 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Prok-RING_4 PF14447.6 KKK18448.1 - 1.2 9.1 20.2 0.082 12.8 9.7 3.1 2 1 1 3 3 2 0 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 KKK18448.1 - 1.9 8.6 12.8 0.032 14.3 5.2 1.9 2 0 0 2 2 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-UBP_var PF17807.1 KKK18448.1 - 3.9 7.3 6.5 0.71 9.7 0.3 2.5 2 0 0 2 2 2 0 Variant UBP zinc finger JIP_LZII PF16471.5 KKK18448.1 - 7.8 6.7 7.7 1.6 8.9 0.2 2.8 3 0 0 3 3 3 0 JNK-interacting protein leucine zipper II Methyltransf_23 PF13489.6 KKK18449.1 - 1.1e-15 57.9 0.0 1.8e-15 57.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KKK18449.1 - 2.6e-12 47.2 0.0 1.8e-11 44.5 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KKK18449.1 - 1.5e-09 38.5 0.0 4.5e-09 37.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKK18449.1 - 5.5e-09 36.6 0.0 6.8e-08 33.1 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KKK18449.1 - 7.3e-09 35.6 0.0 1.5e-08 34.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 KKK18449.1 - 0.11 13.6 0.0 0.22 12.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain TRI12 PF06609.13 KKK18450.1 - 1.5e-28 99.6 27.6 2e-28 99.2 27.6 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 KKK18450.1 - 2.9e-22 79.1 44.2 1e-21 77.3 41.0 2.3 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KKK18450.1 - 1e-08 34.5 4.0 1e-08 34.5 4.0 3.7 3 1 1 4 4 4 1 Sugar (and other) transporter Abhydrolase_3 PF07859.13 KKK18451.1 - 2.2e-26 93.0 0.0 3.1e-26 92.5 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KKK18451.1 - 6.1e-15 54.9 0.0 2.2e-14 53.1 0.0 1.7 1 1 0 1 1 1 1 Steryl acetyl hydrolase Abhydrolase_6 PF12697.7 KKK18451.1 - 0.0025 18.5 0.4 0.0039 17.8 0.4 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KKK18451.1 - 0.0034 16.9 0.0 0.0063 16.0 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family COesterase PF00135.28 KKK18451.1 - 0.045 12.6 0.0 0.076 11.9 0.0 1.3 1 0 0 1 1 1 0 Carboxylesterase family Zn_clus PF00172.18 KKK18461.1 - 1.1e-10 41.5 8.5 2.2e-10 40.5 8.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KKK18461.1 - 5.7e-09 35.4 0.0 9.4e-09 34.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans_2 PF11951.8 KKK18461.1 - 0.037 12.8 0.0 0.93 8.2 0.0 2.4 2 0 0 2 2 2 0 Fungal specific transcription factor domain DUF3455 PF11937.8 KKK18462.1 - 3.6e-43 147.7 0.1 4.5e-43 147.4 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) Myb_DNA-bind_6 PF13921.6 KKK18475.1 - 1.2e-16 60.7 0.0 2.4e-07 30.9 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KKK18475.1 - 9.6e-14 51.3 0.3 4e-07 30.1 0.1 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 KKK18475.1 - 0.0034 17.4 0.0 1.7 8.7 0.0 2.4 2 0 0 2 2 2 2 SLIDE FXR_C1 PF16096.5 KKK18475.1 - 0.28 11.4 4.6 2.9 8.2 0.0 3.6 3 1 0 3 3 3 0 Fragile X-related 1 protein C-terminal region 2 Zn_clus PF00172.18 KKK18476.1 - 1e-05 25.5 8.2 2e-05 24.6 8.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PX PF00787.24 KKK18477.1 - 2.2e-27 95.3 0.2 2.7e-27 95.0 0.2 1.1 1 0 0 1 1 1 1 PX domain RRM_1 PF00076.22 KKK18478.1 - 0.0024 17.7 0.0 0.0043 16.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF5127 PF17168.4 KKK18479.1 - 5.4e-84 281.5 5.2 8.7e-84 280.8 5.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) DUF4965 PF16335.5 KKK18479.1 - 1.6e-79 265.5 1.2 3.5e-79 264.5 1.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4965) DUF1793 PF08760.11 KKK18479.1 - 1.8e-64 217.2 3.8 2e-64 217.1 0.9 2.6 3 1 1 4 4 4 1 Domain of unknown function (DUF1793) DUF4964 PF16334.5 KKK18479.1 - 0.00027 20.4 0.1 0.00096 18.7 0.1 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4964) Annexin PF00191.20 KKK18480.1 - 2.3e-15 56.4 3.0 1.1e-05 25.4 0.1 4.4 4 0 0 4 4 4 4 Annexin Pkinase PF00069.25 KKK18481.1 - 5e-21 75.2 0.0 8.9e-12 44.9 0.0 2.7 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KKK18481.1 - 2.5e-09 36.8 0.1 0.00079 18.8 0.0 3.3 4 0 0 4 4 4 2 Protein tyrosine kinase APH PF01636.23 KKK18481.1 - 0.032 14.2 0.0 0.45 10.4 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.6 KKK18481.1 - 0.22 10.8 0.0 4.9 6.4 0.0 2.5 3 0 0 3 3 3 0 Kinase-like Macoilin PF09726.9 KKK18482.1 - 6.3 5.2 15.4 8.1 4.9 15.4 1.1 1 0 0 1 1 1 0 Macoilin family Septin PF00735.18 KKK18483.1 - 2e-33 115.9 0.0 2.8e-13 49.8 0.0 3.1 3 0 0 3 3 3 3 Septin FtsK_SpoIIIE PF01580.18 KKK18483.1 - 0.002 17.5 0.0 0.0033 16.8 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family Dynamin_N PF00350.23 KKK18483.1 - 0.0023 18.0 0.5 0.01 15.9 0.0 2.3 3 0 0 3 3 3 1 Dynamin family MMR_HSR1 PF01926.23 KKK18483.1 - 0.0038 17.3 0.0 0.0095 16.0 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase G-alpha PF00503.20 KKK18483.1 - 0.051 12.7 0.0 0.13 11.4 0.0 1.6 2 0 0 2 2 2 0 G-protein alpha subunit AAA_16 PF13191.6 KKK18483.1 - 0.06 13.7 0.0 0.18 12.2 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain DOPA_dioxygen PF08883.11 KKK18484.1 - 7.8e-40 135.4 0.0 1.3e-39 134.6 0.0 1.4 1 0 0 1 1 1 1 Dopa 4,5-dioxygenase family Vps62 PF06101.11 KKK18484.1 - 8.5e-11 40.9 2.6 9.7e-11 40.7 1.0 1.8 2 0 0 2 2 2 1 Vacuolar protein sorting-associated protein 62 Ribosomal_L21e PF01157.18 KKK18485.1 - 4.6e-45 151.6 7.8 5.4e-45 151.4 5.7 1.8 2 0 0 2 2 2 1 Ribosomal protein L21e SH3_13 PF18335.1 KKK18485.1 - 0.028 14.2 0.8 0.047 13.5 0.2 1.7 2 1 0 2 2 2 0 ATP-dependent RecD-like DNA helicase SH3 domain 3H PF02829.14 KKK18485.1 - 0.11 12.8 1.3 0.11 12.8 0.3 1.6 2 0 0 2 2 2 0 3H domain WD40 PF00400.32 KKK18486.1 - 3.5e-18 65.6 16.6 0.00058 20.6 0.4 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat Cytochrom_D1 PF02239.16 KKK18486.1 - 4.5e-05 22.2 0.6 0.21 10.1 0.0 3.8 3 1 1 4 4 4 2 Cytochrome D1 heme domain PQQ_3 PF13570.6 KKK18486.1 - 0.0012 19.2 3.1 0.58 10.7 0.1 3.7 3 0 0 3 3 3 2 PQQ-like domain ANAPC4_WD40 PF12894.7 KKK18486.1 - 0.0043 17.3 0.0 0.18 12.1 0.0 3.4 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KKK18486.1 - 0.013 14.9 0.6 0.97 8.7 0.0 2.9 3 0 0 3 3 3 0 WD40-like domain BUD22 PF09073.10 KKK18486.1 - 6.8 5.9 6.9 10 5.4 6.9 1.2 1 0 0 1 1 1 0 BUD22 DUF3584 PF12128.8 KKK18487.1 - 0.00043 18.0 10.0 0.00043 18.0 10.0 1.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3584) BLOC1_2 PF10046.9 KKK18487.1 - 0.0013 19.0 2.9 0.0013 19.0 2.9 3.1 3 1 1 4 4 4 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Baculo_PEP_C PF04513.12 KKK18487.1 - 0.0072 16.4 7.5 0.012 15.7 1.0 2.7 3 0 0 3 3 3 1 Baculovirus polyhedron envelope protein, PEP, C terminus Fez1 PF06818.15 KKK18487.1 - 0.01 16.3 19.9 0.15 12.5 18.7 2.7 2 1 1 3 3 3 0 Fez1 DUF948 PF06103.11 KKK18487.1 - 0.013 15.8 0.9 0.013 15.8 0.9 2.5 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) ABC_tran_CTD PF16326.5 KKK18487.1 - 0.032 14.5 3.1 0.032 14.5 3.1 4.8 2 1 3 5 5 5 0 ABC transporter C-terminal domain Prefoldin PF02996.17 KKK18487.1 - 0.037 13.9 15.3 0.051 13.5 2.5 4.2 2 1 2 4 4 4 0 Prefoldin subunit Ctf8 PF09696.10 KKK18487.1 - 0.11 12.8 6.0 2.5 8.4 5.6 2.8 2 1 0 2 2 2 0 Ctf8 Raptor_N PF14538.6 KKK18487.1 - 0.19 11.7 0.1 0.33 10.9 0.1 1.3 1 0 0 1 1 1 0 Raptor N-terminal CASPase like domain NPV_P10 PF05531.12 KKK18487.1 - 0.21 12.1 4.2 11 6.6 0.5 3.5 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein OmpH PF03938.14 KKK18487.1 - 0.21 11.9 19.8 0.046 14.1 3.2 2.8 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) Prefoldin_2 PF01920.20 KKK18487.1 - 0.55 10.2 20.0 0.25 11.3 3.5 4.2 2 1 1 3 3 3 0 Prefoldin subunit Syntaxin-6_N PF09177.11 KKK18487.1 - 0.66 10.6 11.1 1.8 9.2 1.3 3.8 2 1 2 4 4 4 0 Syntaxin 6, N-terminal APG6_N PF17675.1 KKK18487.1 - 1 9.9 25.3 3.7 8.1 12.0 3.2 2 1 1 3 3 3 0 Apg6 coiled-coil region DUF3552 PF12072.8 KKK18487.1 - 1.7 8.0 19.2 3.2 7.1 4.9 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) DUF1664 PF07889.12 KKK18487.1 - 2 8.5 9.7 0.28 11.2 2.7 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Atg14 PF10186.9 KKK18487.1 - 2 7.4 13.3 2 7.4 11.8 1.8 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 FlaC_arch PF05377.11 KKK18487.1 - 2.7 8.5 10.4 9.5 6.7 0.8 3.9 3 1 0 4 4 4 0 Flagella accessory protein C (FlaC) COG2 PF06148.11 KKK18487.1 - 3 7.9 11.6 0.59 10.2 0.8 2.7 3 0 0 3 3 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Med9 PF07544.13 KKK18487.1 - 3.7 7.7 10.2 1.3 9.2 1.1 3.9 3 1 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 DUF2721 PF11026.8 KKK18487.1 - 3.8 7.4 6.4 0.65 9.9 1.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) Tropomyosin_1 PF12718.7 KKK18487.1 - 3.9 7.6 21.5 1.8 8.7 17.9 2.1 2 0 0 2 2 2 0 Tropomyosin like LMBR1 PF04791.16 KKK18487.1 - 4.4 6.1 4.9 5.2 5.9 4.9 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Tup_N PF08581.10 KKK18487.1 - 4.9 7.5 10.9 2.2 8.6 0.1 3.6 3 2 1 4 4 3 0 Tup N-terminal YabA PF06156.13 KKK18487.1 - 5.3 7.7 14.7 9.2 7.0 1.1 3.6 3 1 0 3 3 3 0 Initiation control protein YabA S4 PF01479.25 KKK18488.1 - 2.2e-12 46.5 0.8 2.2e-12 46.5 0.8 2.3 3 0 0 3 3 3 1 S4 domain Ribosomal_S4 PF00163.19 KKK18488.1 - 5.6e-06 27.2 0.2 1.1e-05 26.3 0.2 1.5 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain Podoplanin PF05808.11 KKK18489.1 - 0.0017 18.5 0.0 0.0017 18.5 0.0 2.2 3 0 0 3 3 3 1 Podoplanin Cu_bind_like PF02298.17 KKK18489.1 - 0.033 14.2 0.3 0.12 12.4 0.3 2.1 1 1 0 1 1 1 0 Plastocyanin-like domain Amnionless PF14828.6 KKK18489.1 - 0.046 12.6 0.0 0.079 11.8 0.0 1.3 1 0 0 1 1 1 0 Amnionless DUF4690 PF15756.5 KKK18489.1 - 0.075 13.6 0.2 0.075 13.6 0.2 2.7 3 0 0 3 3 3 0 Small Novel Rich in Cartilage Plasmodium_Vir PF05795.11 KKK18489.1 - 0.17 11.3 0.3 0.35 10.3 0.0 1.8 2 1 0 2 2 2 0 Plasmodium vivax Vir protein VSP PF03302.13 KKK18489.1 - 0.18 10.6 1.8 0.32 9.8 1.8 1.3 1 0 0 1 1 1 0 Giardia variant-specific surface protein MGC-24 PF05283.11 KKK18489.1 - 0.18 12.2 6.9 0.25 11.8 0.3 2.5 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin TPPK_C PF12555.8 KKK18489.1 - 0.62 10.2 3.8 1.3 9.1 3.8 1.5 1 0 0 1 1 1 0 Thiamine pyrophosphokinase C terminal Pex14_N PF04695.13 KKK18489.1 - 0.62 10.7 18.8 0.37 11.4 5.3 3.2 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SPX PF03105.19 KKK18489.1 - 0.67 9.8 7.5 1.7 8.5 7.5 1.6 1 1 0 1 1 1 0 SPX domain Ribosomal_L4 PF00573.22 KKK18489.1 - 0.78 9.4 2.1 1.4 8.6 2.1 1.5 1 0 0 1 1 1 0 Ribosomal protein L4/L1 family SSP160 PF06933.11 KKK18489.1 - 0.94 7.6 13.9 1.7 6.8 4.7 2.3 2 0 0 2 2 2 0 Special lobe-specific silk protein SSP160 DUF5562 PF17717.1 KKK18489.1 - 1 9.3 11.7 0.53 10.2 1.4 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5562) Dynamin_N PF00350.23 KKK18490.1 - 2.5e-11 43.9 0.0 1.3e-10 41.6 0.0 2.3 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 KKK18490.1 - 7.7e-06 26.0 0.0 0.00016 21.8 0.0 2.7 2 1 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KKK18490.1 - 3.9e-05 23.6 0.1 0.00017 21.5 0.1 2.1 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 KKK18490.1 - 0.00017 22.0 11.0 0.00073 20.0 0.0 4.1 3 1 0 4 4 4 1 AAA ATPase domain ABC_tran PF00005.27 KKK18490.1 - 0.00032 21.2 0.2 0.0049 17.4 0.0 2.7 2 0 0 2 2 2 1 ABC transporter Roc PF08477.13 KKK18490.1 - 0.0047 17.1 0.0 0.017 15.3 0.0 2.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_18 PF13238.6 KKK18490.1 - 0.022 15.3 0.2 0.1 13.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 KKK18490.1 - 0.033 14.5 0.9 0.18 12.1 0.0 2.7 3 0 0 3 3 3 0 AAA domain AAA_29 PF13555.6 KKK18490.1 - 0.052 13.3 0.1 0.15 11.8 0.1 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain Rx_N PF18052.1 KKK18490.1 - 0.91 9.8 6.2 0.73 10.1 0.5 3.1 2 0 0 2 2 2 0 Rx N-terminal domain Baculo_PEP_C PF04513.12 KKK18490.1 - 1.5 8.8 7.3 2.6 8.1 0.1 3.8 4 0 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Sec15 PF04091.12 KKK18490.1 - 1.9 7.8 6.6 0.34 10.3 1.2 2.4 2 1 1 3 3 3 0 Exocyst complex subunit Sec15-like Syntaxin_2 PF14523.6 KKK18490.1 - 3.2 8.2 9.1 2.3 8.6 2.9 3.6 4 0 0 4 4 2 0 Syntaxin-like protein LUC7 PF03194.15 KKK18490.1 - 5.3 6.6 8.3 8.8 5.9 0.9 2.7 2 0 0 2 2 2 0 LUC7 N_terminus AAA_23 PF13476.6 KKK18490.1 - 5.9 7.3 0.0 5.9 7.3 0.0 3.5 3 1 1 4 4 4 0 AAA domain UPF0016 PF01169.19 KKK18491.1 - 2.7e-41 139.8 26.0 1.5e-21 76.5 9.8 2.2 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 DUF3357 PF11837.8 KKK18491.1 - 0.7 10.4 6.2 4.6 7.8 0.3 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF3357) DUF2070 PF09843.9 KKK18491.1 - 1.9 6.7 5.8 0.11 10.8 0.5 1.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2070) Myb_DNA-binding PF00249.31 KKK18492.1 - 7.9e-07 29.2 0.3 1.7e-06 28.1 0.3 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KKK18492.1 - 0.02 15.2 0.0 0.078 13.2 0.0 2.0 2 0 0 2 2 2 0 Myb-like DNA-binding domain SLIDE PF09111.10 KKK18492.1 - 0.14 12.2 0.0 0.32 11.0 0.0 1.6 1 0 0 1 1 1 0 SLIDE Vpu PF00558.19 KKK18492.1 - 2.4 8.0 4.6 4.4 7.2 0.9 2.7 2 0 0 2 2 2 0 Vpu protein MFS_1 PF07690.16 KKK18493.1 - 2e-40 138.8 15.3 2e-40 138.8 15.3 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KKK18493.1 - 6e-15 55.1 5.0 6e-15 55.1 5.0 3.0 2 1 0 3 3 3 1 Sugar (and other) transporter TM140 PF14985.6 KKK18493.1 - 0.03 13.9 0.6 0.11 12.1 0.6 1.9 1 0 0 1 1 1 0 TM140 protein family MFA1_2 PF17317.2 KKK18493.1 - 0.55 10.0 1.8 0.57 10.0 0.0 2.0 2 0 0 2 2 2 0 Mating hormone A-factor 1&2 MFS_1 PF07690.16 KKK18494.1 - 0.00018 20.6 36.2 0.00021 20.4 29.0 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily UvrD_C PF13361.6 KKK18495.1 - 4.2e-62 210.5 0.0 2.2e-59 201.6 0.0 2.3 2 1 0 2 2 2 2 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.21 KKK18495.1 - 3.5e-35 122.0 0.5 7e-35 121.1 0.5 1.5 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.6 KKK18495.1 - 3.5e-14 52.4 0.1 9.8e-14 50.9 0.1 1.8 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 KKK18495.1 - 1.6e-12 47.9 0.5 4.7e-12 46.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.6 KKK18495.1 - 5.2e-05 22.9 0.0 0.0033 17.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KKK18495.1 - 0.089 12.5 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF294_C PF10335.9 KKK18495.1 - 0.13 12.0 0.1 0.24 11.2 0.1 1.4 1 0 0 1 1 1 0 Putative nucleotidyltransferase substrate binding domain Cyt-b5 PF00173.28 KKK18496.1 - 3.6e-14 52.7 0.0 5.3e-14 52.1 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Zip PF02535.22 KKK18497.1 - 6.9e-64 216.2 5.5 8.3e-64 215.9 5.5 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter Saw1 PF11561.8 KKK18498.1 - 0.023 14.2 0.2 0.096 12.2 0.2 1.9 2 0 0 2 2 2 0 Single strand annealing-weakened 1 MRI PF15325.6 KKK18498.1 - 0.25 12.5 3.0 0.42 11.7 2.7 1.5 1 1 0 1 1 1 0 Modulator of retrovirus infection Tom37 PF10568.9 KKK18499.1 - 1.1e-38 132.4 0.8 2e-38 131.5 0.2 1.8 2 0 0 2 2 2 1 Outer mitochondrial membrane transport complex protein GST_C_6 PF17171.4 KKK18499.1 - 1.7e-10 40.5 0.0 6.8e-10 38.6 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 KKK18499.1 - 3.5e-06 27.7 0.1 5.2e-05 23.9 0.0 2.4 2 0 0 2 2 2 1 Glutathione S-transferase N-terminal domain GST_C_2 PF13410.6 KKK18499.1 - 0.00099 19.1 0.1 0.0059 16.6 0.0 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain APH PF01636.23 KKK18500.1 - 0.00079 19.4 0.1 0.0011 19.0 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Asp PF00026.23 KKK18514.1 - 3.4e-74 250.1 4.8 4.5e-74 249.7 4.8 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease tRNA-synt_1b PF00579.25 KKK18514.1 - 1.7e-68 231.1 0.0 2.6e-68 230.5 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) TAXi_N PF14543.6 KKK18514.1 - 2e-13 51.0 7.3 3.3e-12 47.0 5.9 3.0 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KKK18514.1 - 2e-06 28.4 0.5 0.061 14.0 0.2 3.6 2 1 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 KKK18514.1 - 0.0034 17.9 0.0 0.85 10.2 0.0 3.3 3 1 0 3 3 3 1 gag-polyprotein putative aspartyl protease TAXi_C PF14541.6 KKK18514.1 - 0.019 14.7 0.0 0.039 13.7 0.0 1.6 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal Ribosomal_S10 PF00338.22 KKK18515.1 - 3.9e-28 97.6 0.0 5.7e-28 97.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e Erv26 PF04148.13 KKK18516.1 - 3.2e-78 262.3 0.0 3.4e-78 262.2 0.0 1.0 1 0 0 1 1 1 1 Transmembrane adaptor Erv26 PhoR PF11808.8 KKK18516.1 - 6.8 7.2 9.0 0.67 10.4 1.0 2.6 3 0 0 3 3 3 0 Phosphate regulon sensor protein PhoR Cys_Knot_tox PF17486.2 KKK18517.1 - 0.019 15.2 0.4 1.3 9.3 0.0 2.1 1 1 1 2 2 2 0 Cystine knot toxins Antimicrobial_5 PF08026.11 KKK18517.1 - 0.14 12.3 0.1 16 5.6 0.0 2.2 2 0 0 2 2 2 0 Bee antimicrobial peptide DUF1580 PF07618.11 KKK18517.1 - 0.15 11.7 0.1 7.4 6.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1580) KAR9 PF08580.10 KKK18518.1 - 0.0056 15.3 5.2 0.0069 15.0 5.2 1.0 1 0 0 1 1 1 1 Yeast cortical protein KAR9 WBS_methylT PF12589.8 KKK18519.1 - 1.7e-15 57.5 1.9 2.9e-15 56.8 1.9 1.3 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.12 KKK18519.1 - 5.9e-12 46.1 0.0 1e-11 45.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKK18519.1 - 1.6e-11 44.7 0.0 6.3e-11 42.8 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KKK18519.1 - 1.5e-05 25.7 0.0 4.1e-05 24.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KKK18519.1 - 3.8e-05 23.5 0.0 5.7e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KKK18519.1 - 0.0013 18.5 0.0 0.0022 17.8 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.6 KKK18519.1 - 0.0042 16.9 0.0 0.0062 16.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KKK18519.1 - 0.0047 16.3 0.1 0.052 12.9 0.0 2.2 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family CMAS PF02353.20 KKK18519.1 - 0.019 14.3 0.0 0.27 10.5 0.0 2.0 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase Methyltransf_33 PF10017.9 KKK18519.1 - 0.077 12.1 0.0 0.16 11.1 0.0 1.4 1 1 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent Iso_dh PF00180.20 KKK18520.1 - 1.2e-83 281.2 0.0 1.5e-83 280.8 0.0 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Proteasome PF00227.26 KKK18521.1 - 7.4e-47 159.3 0.2 5.7e-32 110.7 0.0 2.3 2 0 0 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.9 KKK18521.1 - 2.5e-12 46.2 0.3 6.3e-12 44.9 0.0 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Cyclin PF08613.11 KKK18553.1 - 6.9e-07 29.8 0.6 7.5e-06 26.4 0.0 2.4 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.23 KKK18553.1 - 0.0017 18.1 0.1 0.0037 17.0 0.1 1.6 1 1 0 1 1 1 1 Cyclin, N-terminal domain Pyrid_oxidase_2 PF13883.6 KKK18554.1 - 1.9e-36 125.6 0.0 2.5e-36 125.2 0.0 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase AreA_N PF07573.11 KKK18555.1 - 7.4e-23 81.0 9.0 7.4e-23 81.0 9.0 4.8 4 2 1 5 5 5 1 Nitrogen regulatory protein AreA N terminus GATA PF00320.27 KKK18555.1 - 4e-16 58.3 2.3 8.1e-16 57.3 2.3 1.5 1 0 0 1 1 1 1 GATA zinc finger DUF1752 PF08550.10 KKK18555.1 - 2.2e-12 46.6 2.2 4.2e-12 45.7 2.2 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Ipi1_N PF12333.8 KKK18556.1 - 2.4e-26 92.3 0.3 2.4e-26 92.3 0.3 2.2 2 1 0 2 2 2 1 Rix1 complex component involved in 60S ribosome maturation PAN_4 PF14295.6 KKK18557.1 - 2.6e-07 30.5 31.7 0.0076 16.1 5.7 5.1 4 0 0 4 4 4 4 PAN domain PAN_3 PF08277.12 KKK18557.1 - 0.00017 21.3 33.7 0.007 16.2 2.5 5.2 5 0 0 5 5 5 3 PAN-like domain PAN_2 PF08276.11 KKK18557.1 - 0.11 12.6 34.5 1.7 8.8 5.6 4.9 4 0 0 4 4 4 0 PAN-like domain Mito_fiss_reg PF05308.11 KKK18557.1 - 0.72 9.9 4.3 1.7 8.6 4.3 1.7 1 0 0 1 1 1 0 Mitochondrial fission regulator VWA_2 PF13519.6 KKK18558.1 - 0.061 14.0 0.1 0.23 12.1 0.1 2.0 1 0 0 1 1 1 0 von Willebrand factor type A domain Transp_cyt_pur PF02133.15 KKK18559.1 - 1e-90 304.6 43.2 1.2e-90 304.4 43.2 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Pkinase PF00069.25 KKK18560.1 - 1.4e-16 60.7 0.0 8.5e-15 54.8 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK18560.1 - 0.00076 18.8 0.0 0.0016 17.8 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase PIG-L PF02585.17 KKK18564.1 - 2.6e-27 96.0 0.0 3.3e-27 95.7 0.0 1.1 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase Vir_act_alpha_C PF10400.9 KKK18572.1 - 0.05 14.3 0.2 0.13 13.0 0.1 1.6 2 0 0 2 2 2 0 Virulence activator alpha C-term zf-C2H2 PF00096.26 KKK18573.1 - 1e-06 28.9 9.7 0.00048 20.4 0.4 3.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 KKK18573.1 - 1.3e-05 25.4 2.2 0.11 12.8 0.0 3.0 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding Fungal_trans PF04082.18 KKK18573.1 - 2.5e-05 23.5 0.1 8.9e-05 21.6 0.1 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Atg14 PF10186.9 KKK18573.1 - 0.0013 17.9 0.2 0.19 10.8 0.1 2.2 2 0 0 2 2 2 2 Vacuolar sorting 38 and autophagy-related subunit 14 zf-C2H2_6 PF13912.6 KKK18573.1 - 0.0032 17.4 7.1 0.045 13.8 0.1 2.9 2 0 0 2 2 2 1 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KKK18573.1 - 0.0042 17.5 5.3 0.0042 17.5 5.3 3.2 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KKK18573.1 - 0.0052 17.5 0.4 0.0052 17.5 0.4 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.7 KKK18573.1 - 0.45 11.0 2.3 12 6.5 0.1 3.1 3 0 0 3 3 3 0 Zinc-finger of C2H2 type LIM PF00412.22 KKK18573.1 - 0.94 9.8 4.3 3.8 7.8 4.3 2.1 1 0 0 1 1 1 0 LIM domain zf-C2H2_11 PF16622.5 KKK18573.1 - 1.3 8.8 4.7 7.7 6.4 0.0 2.9 2 0 0 2 2 2 0 zinc-finger C2H2-type 4HBT_3 PF13622.6 KKK18575.1 - 1.7e-36 126.7 0.1 2e-36 126.5 0.1 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily Dmrt1 PF12374.8 KKK18577.1 - 0.6 10.6 4.3 0.28 11.7 0.7 2.2 2 1 1 3 3 3 0 Double-sex mab3 related transcription factor 1 MFS_1 PF07690.16 KKK18579.1 - 1.9e-40 138.9 14.8 3e-40 138.3 14.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KKK18579.1 - 8.9e-12 44.6 21.2 1.4e-10 40.7 5.2 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.13 KKK18579.1 - 3.7e-08 32.3 4.2 8.2e-07 27.8 1.2 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) DUF2207 PF09972.9 KKK18579.1 - 1.4 7.6 4.3 8.3 5.0 0.4 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) B12-binding PF02310.19 KKK18580.1 - 0.00025 21.1 0.0 0.00036 20.6 0.0 1.2 1 0 0 1 1 1 1 B12 binding domain FtsK_SpoIIIE PF01580.18 KKK18580.1 - 0.033 13.5 0.0 0.033 13.5 0.0 1.1 1 0 0 1 1 1 0 FtsK/SpoIIIE family RraA-like PF03737.15 KKK18586.1 - 1.4e-27 96.7 0.1 1.9e-27 96.3 0.1 1.2 1 0 0 1 1 1 1 Aldolase/RraA Acetyltransf_2 PF00797.17 KKK18587.1 - 1.2e-38 133.3 0.0 1.6e-38 132.8 0.0 1.2 1 0 0 1 1 1 1 N-acetyltransferase Thiolase_N PF00108.23 KKK18588.1 - 1.8e-72 243.9 5.2 1.8e-72 243.9 5.2 1.5 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KKK18588.1 - 1.2e-43 147.7 0.2 2.9e-43 146.4 0.2 1.7 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KKK18588.1 - 0.0048 16.5 1.0 0.036 13.7 0.4 2.5 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain MOZ_SAS PF01853.18 KKK18589.1 - 5.5e-75 251.0 0.0 8.8e-75 250.3 0.0 1.3 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 KKK18589.1 - 2.3e-21 75.2 3.8 5e-21 74.1 3.8 1.5 1 0 0 1 1 1 1 MYST family zinc finger domain PHD_4 PF16866.5 KKK18589.1 - 2.1e-12 46.9 7.1 6e-12 45.5 7.1 1.8 1 0 0 1 1 1 1 PHD-finger PHD PF00628.29 KKK18589.1 - 0.00018 21.3 8.7 0.00018 21.3 8.7 2.1 2 0 0 2 2 2 1 PHD-finger zf-MIZ PF02891.20 KKK18589.1 - 0.13 12.0 1.6 0.31 10.8 1.6 1.6 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-RING_9 PF13901.6 KKK18589.1 - 0.98 9.4 4.6 1.7 8.6 4.6 1.3 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon BTB_2 PF02214.22 KKK18590.1 - 3.5e-08 33.7 0.0 7e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KKK18590.1 - 6.3e-05 23.2 0.0 0.0001 22.5 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain DUF4588 PF15251.6 KKK18591.1 - 1.6e-06 28.1 0.2 1.6e-06 28.1 0.2 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF4588) Glyco_tranf_2_2 PF10111.9 KKK18591.1 - 0.1 12.0 0.0 0.15 11.5 0.0 1.1 1 0 0 1 1 1 0 Glycosyltransferase like family 2 MGC-24 PF05283.11 KKK18591.1 - 9.1 6.7 8.1 2.2 8.7 3.3 2.1 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin SNF2_N PF00176.23 KKK18592.1 - 6.3e-77 258.7 0.4 1.3e-76 257.7 0.4 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.10 KKK18592.1 - 6.8e-44 148.5 0.9 6.8e-44 148.5 0.9 2.1 2 0 0 2 2 1 1 SLIDE HAND PF09110.11 KKK18592.1 - 8.1e-38 129.6 1.3 8.1e-38 129.6 1.3 3.3 3 0 0 3 3 3 1 HAND Helicase_C PF00271.31 KKK18592.1 - 5.1e-18 65.4 0.7 3.9e-17 62.6 0.0 2.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KKK18592.1 - 3.1e-11 43.6 0.0 1.5e-10 41.3 0.0 2.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 KKK18592.1 - 6.1e-06 25.6 0.1 5e-05 22.6 0.0 2.4 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.29 KKK18592.1 - 0.00031 20.6 0.0 0.00081 19.2 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 KKK18592.1 - 0.00039 20.2 0.0 0.0012 18.6 0.0 1.8 1 0 0 1 1 1 1 SWI2/SNF2 ATPase AAA_14 PF13173.6 KKK18592.1 - 0.023 14.7 0.0 0.09 12.8 0.0 2.0 1 0 0 1 1 1 0 AAA domain DEAD_2 PF06733.15 KKK18592.1 - 0.063 12.9 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 DEAD_2 Tn7_Tnp_TnsA_C PF08721.11 KKK18592.1 - 0.12 13.0 0.4 0.57 10.9 0.1 2.3 2 0 0 2 2 2 0 TnsA endonuclease C terminal Occludin_ELL PF07303.13 KKK18592.1 - 0.17 12.6 4.0 0.68 10.7 4.0 2.0 1 0 0 1 1 1 0 Occludin homology domain DUF5618 PF18498.1 KKK18592.1 - 8.9 6.5 7.5 5.6 7.2 0.8 3.3 4 0 0 4 4 4 0 Domain of unknown function (DUF5618) FKBP_N PF01346.18 KKK18592.1 - 9.1 7.3 9.9 6.8 7.7 1.0 3.9 3 1 1 4 4 4 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase Adap_comp_sub PF00928.21 KKK18593.1 - 3.7e-62 210.1 0.0 1e-51 175.9 0.0 2.1 2 0 0 2 2 2 2 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KKK18593.1 - 0.00012 22.0 0.4 0.00024 21.1 0.4 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain TFIIF_alpha PF05793.12 KKK18593.1 - 0.19 10.3 10.3 0.27 9.8 10.3 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) FTCD_C PF04961.12 KKK18593.1 - 0.21 11.3 1.0 0.39 10.5 1.0 1.3 1 0 0 1 1 1 0 Formiminotransferase-cyclodeaminase SPT6_acidic PF14632.6 KKK18593.1 - 1.3 9.7 6.5 2.2 8.9 6.5 1.3 1 0 0 1 1 1 0 Acidic N-terminal SPT6 DUF4536 PF15055.6 KKK18594.1 - 1.4e-07 31.6 0.2 1.9e-07 31.2 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4536) MWFE PF15879.5 KKK18595.1 - 1.4e-26 92.4 0.2 1.7e-26 92.1 0.2 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase MWFE subunit AAA_23 PF13476.6 KKK18607.1 - 6.2e-34 118.3 2.6 6.2e-34 118.3 2.6 8.3 2 2 0 3 3 3 1 AAA domain SbcCD_C PF13558.6 KKK18607.1 - 3.4e-06 27.2 0.0 1.1e-05 25.6 0.0 1.9 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit SMC_N PF02463.19 KKK18607.1 - 1.6e-05 24.4 0.0 1.6e-05 24.4 0.0 3.6 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain KNOX2 PF03791.13 KKK18607.1 - 0.00016 21.1 0.0 0.0078 15.7 0.0 3.4 2 0 0 2 2 2 1 KNOX2 domain AAA_21 PF13304.6 KKK18607.1 - 0.0011 18.8 12.4 2.6 7.8 8.3 4.3 2 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KKK18607.1 - 0.1 12.4 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 KKK18607.1 - 1.3 9.4 0.0 1.3 9.4 0.0 5.8 5 3 0 5 5 5 0 AAA ATPase domain Baculo_PEP_C PF04513.12 KKK18607.1 - 3.7 7.6 46.6 0.08 13.0 3.2 8.3 5 2 2 7 7 7 0 Baculovirus polyhedron envelope protein, PEP, C terminus DASH_Dam1 PF08653.10 KKK18607.1 - 6.7 6.6 10.0 10 6.0 0.4 5.4 5 0 0 5 5 5 0 DASH complex subunit Dam1 Rad1 PF02144.16 KKK18608.1 - 1.1e-92 310.1 0.2 1.2e-92 309.9 0.2 1.0 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Ost5 PF05251.12 KKK18609.1 - 1.4e-19 70.1 11.5 1.6e-19 69.9 11.5 1.1 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit 5 DUF485 PF04341.12 KKK18609.1 - 0.08 12.9 2.4 0.091 12.7 2.4 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF485 Bromodomain PF00439.25 KKK18610.1 - 4.6e-23 81.1 1.0 9.2e-23 80.1 1.0 1.5 1 0 0 1 1 1 1 Bromodomain Acetyltransf_1 PF00583.25 KKK18610.1 - 1.5e-08 34.9 0.0 3.3e-08 33.8 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KKK18610.1 - 1.4e-07 31.5 0.4 8.6e-07 28.9 0.1 2.1 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KKK18610.1 - 9.9e-05 22.7 0.2 0.00037 20.9 0.1 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KKK18610.1 - 0.19 11.7 0.0 0.37 10.8 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein PPP4R2 PF09184.11 KKK18611.1 - 5.3e-10 39.4 1.1 7e-09 35.7 0.8 2.2 1 1 0 1 1 1 1 PPP4R2 HMA PF00403.26 KKK18612.1 - 4.5e-48 161.5 1.8 4e-12 46.4 0.1 4.5 4 0 0 4 4 4 4 Heavy-metal-associated domain E1-E2_ATPase PF00122.20 KKK18612.1 - 3.6e-47 160.2 0.8 3.6e-47 160.2 0.8 2.8 3 1 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 KKK18612.1 - 2.3e-37 129.3 0.2 4.4e-37 128.4 0.2 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KKK18612.1 - 0.00063 19.6 1.4 0.00092 19.0 0.1 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase B12-binding PF02310.19 KKK18612.1 - 0.002 18.1 0.2 3 7.9 0.0 4.1 4 0 0 4 4 4 1 B12 binding domain MtrH PF02007.18 KKK18612.1 - 0.051 12.7 0.2 0.14 11.2 0.2 1.7 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase MtrH subunit PCI PF01399.27 KKK18613.1 - 0.01 16.3 0.0 0.017 15.6 0.0 1.3 1 0 0 1 1 1 0 PCI domain CSN7a_helixI PF18392.1 KKK18613.1 - 0.012 15.5 1.6 0.016 15.1 0.5 1.8 1 1 1 2 2 2 0 COP9 signalosome complex subunit 7a helix I domain RGS PF00615.19 KKK18614.1 - 1.1e-11 45.0 0.0 1.8e-08 34.7 0.0 2.3 2 0 0 2 2 2 2 Regulator of G protein signaling domain NMN_transporter PF04973.12 KKK18614.1 - 0.17 11.8 3.3 0.31 11.0 3.3 1.4 1 0 0 1 1 1 0 Nicotinamide mononucleotide transporter NARP1 PF12569.8 KKK18615.1 - 6.2e-219 728.2 25.0 8.9e-217 721.1 16.2 2.5 3 0 0 3 3 3 2 NMDA receptor-regulated protein 1 TPR_19 PF14559.6 KKK18615.1 - 1.5e-15 57.4 31.5 0.0094 16.4 1.1 7.8 8 0 0 8 8 7 6 Tetratricopeptide repeat TPR_14 PF13428.6 KKK18615.1 - 6.3e-15 54.6 27.3 0.01 16.6 0.3 11.2 9 3 4 13 13 10 5 Tetratricopeptide repeat TPR_2 PF07719.17 KKK18615.1 - 1.2e-14 53.2 45.5 0.00022 21.1 0.5 11.7 14 0 0 14 14 11 5 Tetratricopeptide repeat TPR_16 PF13432.6 KKK18615.1 - 7.6e-13 48.9 29.3 0.0099 16.5 0.8 10.0 9 1 2 11 11 11 3 Tetratricopeptide repeat ANAPC3 PF12895.7 KKK18615.1 - 2.4e-09 37.3 19.5 5.2e-07 29.8 2.3 5.6 4 1 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 KKK18615.1 - 1.8e-07 30.7 25.9 0.00023 20.8 0.2 7.7 9 0 0 9 9 8 2 TPR repeat TPR_12 PF13424.6 KKK18615.1 - 2.8e-07 30.7 27.2 0.23 11.8 0.1 9.0 9 1 0 9 9 8 2 Tetratricopeptide repeat TPR_9 PF13371.6 KKK18615.1 - 4.9e-07 29.8 11.9 0.032 14.4 2.9 6.0 5 2 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 KKK18615.1 - 1e-06 28.7 14.7 0.14 12.6 0.0 7.3 8 0 0 8 8 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 KKK18615.1 - 2.9e-05 23.9 38.3 0.00099 19.2 0.2 9.3 11 0 0 11 11 8 2 Tetratricopeptide repeat TPR_1 PF00515.28 KKK18615.1 - 5.1e-05 22.9 37.9 5.3e-05 22.9 0.4 9.7 12 0 0 12 12 11 1 Tetratricopeptide repeat TPR_MalT PF17874.1 KKK18615.1 - 0.00031 20.2 8.3 0.54 9.6 1.3 3.6 2 1 1 3 3 3 2 MalT-like TPR region Rapsyn_N PF10579.9 KKK18615.1 - 0.0024 17.9 3.1 0.32 11.1 0.1 4.1 2 1 1 3 3 3 1 Rapsyn N-terminal myristoylation and linker region DUF4290 PF14123.6 KKK18615.1 - 0.01 15.4 1.1 0.026 14.1 1.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4290) TPR_6 PF13174.6 KKK18615.1 - 0.011 16.4 23.8 0.7 10.7 0.2 9.0 10 0 0 10 10 9 0 Tetratricopeptide repeat BTAD PF03704.17 KKK18615.1 - 0.016 15.7 0.2 0.016 15.7 0.2 4.2 5 0 0 5 5 4 0 Bacterial transcriptional activator domain TPR_4 PF07721.14 KKK18615.1 - 0.054 14.1 4.3 0.41 11.4 0.1 4.3 5 0 0 5 5 2 0 Tetratricopeptide repeat TPR_3 PF07720.12 KKK18615.1 - 0.21 11.6 3.7 2.2 8.3 0.2 3.8 3 0 0 3 3 2 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KKK18615.1 - 1.3 9.1 13.6 13 6.0 0.1 5.7 7 1 0 7 7 6 0 Fis1 C-terminal tetratricopeptide repeat TPR_7 PF13176.6 KKK18615.1 - 2 8.6 14.6 15 5.9 0.0 6.7 9 0 0 9 9 6 0 Tetratricopeptide repeat L31 PF09784.9 KKK18615.1 - 2.5 8.6 5.4 0.92 10.0 1.8 2.1 2 0 0 2 2 1 0 Mitochondrial ribosomal protein L31 TPR_10 PF13374.6 KKK18615.1 - 4.5 7.3 21.8 4.5 7.3 0.0 6.6 7 0 0 7 7 6 0 Tetratricopeptide repeat DUF4449 PF14613.6 KKK18616.1 - 5e-61 205.6 11.8 7.1e-61 205.1 0.1 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF4449) Prp18 PF02840.15 KKK18616.1 - 9.4 6.3 8.6 6 6.9 0.0 3.7 3 1 1 4 4 4 0 Prp18 domain AIRC PF00731.20 KKK18617.1 - 1.4e-58 196.7 2.5 2.9e-58 195.6 2.5 1.6 1 0 0 1 1 1 1 AIR carboxylase ATP-grasp PF02222.22 KKK18617.1 - 7e-52 175.5 0.1 2.3e-51 173.8 0.0 1.8 2 0 0 2 2 2 1 ATP-grasp domain PurK_C PF17769.1 KKK18617.1 - 2.8e-18 65.3 0.6 8.3e-18 63.8 0.2 2.1 2 0 0 2 2 2 1 Phosphoribosylaminoimidazole carboxylase C-terminal domain CPSase_L_D2 PF02786.17 KKK18617.1 - 1.5e-06 27.9 0.0 3.8e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain AlaDh_PNT_C PF01262.21 KKK18617.1 - 1.9e-06 27.4 0.1 4.4e-06 26.1 0.1 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Dala_Dala_lig_C PF07478.13 KKK18617.1 - 0.00026 20.6 0.0 0.0024 17.4 0.0 2.2 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus 2-Hacid_dh_C PF02826.19 KKK18617.1 - 0.0059 16.0 0.0 0.012 15.0 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PrpR_N PF06506.11 KKK18617.1 - 0.012 15.1 0.4 0.18 11.4 0.1 2.5 2 0 0 2 2 2 0 Propionate catabolism activator NAD_binding_2 PF03446.15 KKK18617.1 - 0.015 15.4 0.0 0.04 14.1 0.0 1.8 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 KKK18617.1 - 0.018 15.0 0.2 0.048 13.5 0.2 1.8 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ATP-grasp_5 PF13549.6 KKK18617.1 - 0.026 14.0 0.0 0.055 12.9 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain XdhC_C PF13478.6 KKK18617.1 - 0.029 14.9 0.1 0.22 12.0 0.1 2.3 1 1 1 2 2 2 0 XdhC Rossmann domain Peptidase_M15_3 PF08291.11 KKK18617.1 - 0.033 14.3 0.0 40 4.3 0.0 3.8 3 1 0 3 3 3 0 Peptidase M15 ATP-grasp_3 PF02655.14 KKK18617.1 - 0.052 13.6 0.0 0.2 11.7 0.0 1.9 2 0 0 2 2 2 0 ATP-grasp domain Asp-B-Hydro_N PF05279.11 KKK18622.1 - 1.4 9.0 5.8 3 7.8 5.8 1.5 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Thioredoxin PF00085.20 KKK18623.1 - 5.2e-18 64.9 0.4 8.9e-18 64.2 0.4 1.5 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 KKK18623.1 - 0.00014 22.1 0.0 0.00017 21.8 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 KKK18623.1 - 0.0041 17.0 0.0 0.0048 16.8 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KKK18623.1 - 0.0056 16.4 0.3 0.0063 16.2 0.3 1.3 1 1 0 1 1 1 1 Redoxin Thioredoxin_9 PF14595.6 KKK18623.1 - 0.07 12.9 0.0 0.087 12.6 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_7 PF13899.6 KKK18623.1 - 0.071 13.3 0.0 0.093 12.9 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like Thioredoxin_2 PF13098.6 KKK18623.1 - 0.076 13.5 0.2 0.15 12.6 0.2 1.5 1 1 1 2 2 2 0 Thioredoxin-like domain Kelch_4 PF13418.6 KKK18624.1 - 6.7e-22 77.2 7.7 8.2e-08 32.1 0.0 5.0 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_6 PF13964.6 KKK18624.1 - 3.5e-21 74.7 1.1 3.9e-05 23.8 0.0 5.0 3 1 1 4 4 4 4 Kelch motif Kelch_5 PF13854.6 KKK18624.1 - 9.9e-21 73.3 0.6 1.2e-05 25.1 0.1 5.2 5 0 0 5 5 5 4 Kelch motif Kelch_3 PF13415.6 KKK18624.1 - 2.6e-18 65.8 2.6 4e-07 30.2 0.1 5.2 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_1 PF01344.25 KKK18624.1 - 4.8e-17 61.3 0.1 8.8e-05 22.0 0.0 4.2 4 0 0 4 4 4 3 Kelch motif Kelch_2 PF07646.15 KKK18624.1 - 5e-17 61.1 0.2 5.2e-05 23.0 0.0 4.4 4 0 0 4 4 4 3 Kelch motif BTB PF00651.31 KKK18624.1 - 3.2e-09 37.0 0.0 6.3e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.15 KKK18624.1 - 0.051 13.7 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 BTB And C-terminal Kelch ANAPC4_WD40 PF12894.7 KKK18625.1 - 4.2e-17 62.2 2.5 1.2e-05 25.5 0.1 4.3 2 1 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KKK18625.1 - 9.4e-16 57.9 17.6 5.1e-05 24.0 0.0 6.4 7 0 0 7 7 7 5 WD domain, G-beta repeat Ge1_WD40 PF16529.5 KKK18625.1 - 2.6e-06 26.6 0.0 0.00086 18.4 0.0 3.1 2 1 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KKK18625.1 - 0.00011 22.1 0.2 0.0079 16.1 0.1 2.5 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A Amidase PF01425.21 KKK18626.1 - 1.3e-05 24.4 0.0 0.11 11.4 0.0 2.5 2 1 0 2 2 2 2 Amidase Glyco_hydro_1 PF00232.18 KKK18627.1 - 1e-151 505.4 0.0 1.3e-151 505.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 AID PF18767.1 KKK18627.1 - 0.0067 16.4 0.0 0.014 15.4 0.0 1.5 1 0 0 1 1 1 1 Activation induced deaminase Sel1 PF08238.12 KKK18628.1 - 1.7e-34 117.4 38.9 8.5e-06 26.3 0.1 11.6 12 1 0 12 12 12 8 Sel1 repeat TPR_16 PF13432.6 KKK18628.1 - 0.0043 17.7 10.6 6.1 7.6 0.2 5.5 4 2 2 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 KKK18628.1 - 0.023 14.9 7.5 28 5.3 0.1 6.3 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.6 KKK18628.1 - 1 9.5 8.9 9.5 6.5 0.1 4.9 6 0 0 6 6 6 0 Tetratricopeptide repeat Mei5 PF10376.9 KKK18629.1 - 0.0059 16.5 11.4 0.24 11.3 11.4 2.7 1 1 0 1 1 1 1 Double-strand recombination repair protein GTP-bdg_M PF16360.5 KKK18629.1 - 0.018 15.6 1.7 0.18 12.4 0.1 2.5 2 1 0 2 2 2 0 GTP-binding GTPase Middle Region Mut7-C PF01927.16 KKK18629.1 - 0.08 13.0 0.3 0.84 9.7 0.0 2.2 2 0 0 2 2 2 0 Mut7-C RNAse domain DUF1943 PF09172.11 KKK18629.1 - 0.087 12.0 0.9 0.25 10.5 0.9 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF1943) OmpH PF03938.14 KKK18629.1 - 5.5 7.3 7.7 42 4.5 7.7 2.3 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) WD40 PF00400.32 KKK18630.1 - 1.5e-14 54.2 9.0 3.8e-05 24.4 0.2 5.3 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKK18630.1 - 3e-10 40.3 0.6 0.014 15.6 0.0 4.0 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KKK18630.1 - 0.0017 18.2 0.0 1.1 9.1 0.0 2.8 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 KKK18630.1 - 0.038 12.5 0.0 0.085 11.4 0.0 1.6 1 0 0 1 1 1 0 Cytochrome D1 heme domain Mesothelin PF06060.12 KKK18630.1 - 0.2 9.8 0.1 0.26 9.4 0.1 1.1 1 0 0 1 1 1 0 Pre-pro-megakaryocyte potentiating factor precursor (Mesothelin) RNA_pol_Rpb1_1 PF04997.12 KKK18631.1 - 1.9e-114 382.2 0.0 3e-114 381.6 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 KKK18631.1 - 7.8e-104 346.8 0.0 1.4e-103 346.0 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 KKK18631.1 - 2.8e-77 258.6 0.0 6.7e-77 257.4 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.14 KKK18631.1 - 2.6e-65 219.9 1.4 4.9e-65 218.9 1.4 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.18 KKK18631.1 - 5.3e-46 156.4 0.0 1.4e-45 155.0 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.12 KKK18631.1 - 2.4e-44 150.6 7.4 2.4e-44 150.6 7.4 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.17 KKK18631.1 - 4.4e-37 126.3 0.1 1e-36 125.1 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.13 KKK18631.1 - 7.6e-21 73.3 194.0 0.0015 18.8 0.1 14.5 11 2 2 13 13 13 13 RNA polymerase Rpb1 C-terminal repeat GST_N_4 PF17172.4 KKK18632.1 - 3.8e-25 88.5 0.0 5.5e-25 88.0 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 KKK18632.1 - 1.7e-06 27.7 0.0 4.7e-06 26.3 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KKK18632.1 - 6.4e-05 22.9 0.0 0.00014 21.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 KKK18632.1 - 6.7e-05 23.2 0.0 9.6e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_N_3 PF13417.6 KKK18632.1 - 0.00015 22.1 0.0 0.00078 19.8 0.0 2.0 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain TFIIA PF03153.13 KKK18633.1 - 1.5e-88 298.6 0.2 1.7e-88 298.4 0.2 1.0 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit SCA7 PF08313.12 KKK18645.1 - 3.4e-31 106.9 1.1 1e-30 105.4 1.1 1.9 1 0 0 1 1 1 1 SCA7, zinc-binding domain OrsD PF12013.8 KKK18645.1 - 0.022 15.2 1.1 0.12 12.8 0.1 2.4 2 0 0 2 2 2 0 Orsellinic acid/F9775 biosynthesis cluster protein D Cut8 PF08559.10 KKK18645.1 - 0.026 14.1 1.9 0.048 13.3 1.9 1.4 1 0 0 1 1 1 0 Cut8, nuclear proteasome tether protein CDC45 PF02724.14 KKK18645.1 - 0.32 9.2 10.3 0.41 8.9 10.3 1.2 1 0 0 1 1 1 0 CDC45-like protein ketoacyl-synt PF00109.26 KKK18646.1 - 1.6e-61 208.1 3.4 3.8e-61 206.9 0.4 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 KKK18646.1 - 6.3e-33 113.3 1.9 2.4e-32 111.4 1.4 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 KKK18646.1 - 0.00012 21.6 0.7 0.0004 19.8 0.1 1.9 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KKK18646.1 - 0.0094 15.6 2.3 0.15 11.7 0.4 3.0 3 0 0 3 3 3 1 Thiolase, C-terminal domain Ribophorin_I PF04597.14 KKK18647.1 - 9e-151 503.0 0.6 1e-150 502.8 0.6 1.0 1 0 0 1 1 1 1 Ribophorin I mRNA_cap_enzyme PF01331.19 KKK18648.1 - 3.5e-52 177.1 0.2 4.5e-52 176.7 0.2 1.2 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.15 KKK18648.1 - 6.1e-33 113.7 0.0 1.3e-32 112.6 0.0 1.6 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.21 KKK18648.1 - 1.8e-08 34.3 0.2 4.6e-07 29.7 0.1 2.3 1 1 1 2 2 2 1 ATP dependent DNA ligase domain RNA_ligase PF09414.10 KKK18648.1 - 0.0006 20.2 0.1 0.0014 18.9 0.0 1.6 2 0 0 2 2 2 1 RNA ligase DLH PF01738.18 KKK18649.1 - 4.1e-05 23.2 0.0 7.7e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Dienelactone hydrolase family SnoaL PF07366.12 KKK18649.1 - 0.0012 18.6 0.0 0.0017 18.2 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 KKK18649.1 - 0.0032 18.1 0.0 0.0073 16.9 0.0 1.6 1 0 0 1 1 1 1 SnoaL-like domain Indigoidine_A PF04227.12 KKK18650.1 - 8.1e-115 383.2 0.4 3.5e-113 377.8 0.4 2.2 1 1 0 1 1 1 1 Indigoidine synthase A like protein PfkB PF00294.24 KKK18650.1 - 7.9e-19 68.1 4.4 2e-11 43.8 0.2 2.8 2 1 0 2 2 2 2 pfkB family carbohydrate kinase LSM PF01423.22 KKK18656.1 - 6.8e-20 70.5 0.0 7.6e-20 70.4 0.0 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KKK18656.1 - 0.00033 20.7 0.1 0.00041 20.4 0.1 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.7 KKK18656.1 - 0.00048 20.2 0.2 0.00057 19.9 0.2 1.1 1 0 0 1 1 1 1 Scd6-like Sm domain His_Phos_2 PF00328.22 KKK18657.1 - 8.9e-111 370.9 0.2 1.3e-110 370.4 0.2 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PPIP5K2_N PF18086.1 KKK18657.1 - 5.4e-38 129.0 0.0 1.3e-37 127.8 0.0 1.6 1 0 0 1 1 1 1 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain RimK PF08443.11 KKK18657.1 - 3.9e-05 23.3 0.0 9.4e-05 22.1 0.0 1.5 1 0 0 1 1 1 1 RimK-like ATP-grasp domain Mito_fiss_reg PF05308.11 KKK18657.1 - 0.0058 16.7 4.7 0.017 15.3 4.7 1.9 1 0 0 1 1 1 1 Mitochondrial fission regulator PRIMA1 PF16101.5 KKK18657.1 - 2.4 8.2 5.1 5.5 7.0 5.1 1.6 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 N-SET PF11764.8 KKK18658.1 - 2.1e-57 194.0 0.8 2.1e-57 194.0 0.8 3.0 3 0 0 3 3 3 1 COMPASS (Complex proteins associated with Set1p) component N SET_assoc PF11767.8 KKK18658.1 - 9.6e-28 95.6 0.5 2.8e-27 94.1 0.5 1.9 1 0 0 1 1 1 1 Histone lysine methyltransferase SET associated SET PF00856.28 KKK18658.1 - 2.2e-18 67.2 0.1 2.2e-18 67.2 0.1 3.2 3 1 0 3 3 3 1 SET domain RRM_1 PF00076.22 KKK18658.1 - 0.00016 21.4 0.0 0.00041 20.1 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Rad60-SLD PF11976.8 KKK18659.1 - 1.4e-19 69.7 0.0 1.4e-16 60.1 0.1 2.4 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 KKK18659.1 - 0.00038 20.2 0.0 0.12 12.2 0.0 2.5 2 0 0 2 2 2 2 Ubiquitin family DMRL_synthase PF00885.19 KKK18660.1 - 3e-56 189.2 0.0 3.4e-56 189.0 0.0 1.0 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase SIS PF01380.22 KKK18661.1 - 5e-59 197.9 0.0 3e-32 111.2 0.1 2.3 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 KKK18661.1 - 6.2e-18 65.3 0.0 1.2e-17 64.4 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 KKK18661.1 - 1.6e-10 41.0 0.0 3.1e-10 40.0 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 KKK18661.1 - 5.9e-05 22.1 0.0 9.3e-05 21.4 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Holin_BhlA PF10960.8 KKK18661.1 - 0.1 12.6 0.0 0.32 11.0 0.0 1.8 1 0 0 1 1 1 0 BhlA holin family GATase_2 PF00310.21 KKK18661.1 - 0.11 11.1 0.0 0.26 10.0 0.0 1.5 2 0 0 2 2 2 0 Glutamine amidotransferases class-II Sec2p PF06428.11 KKK18662.1 - 2.1e-28 98.1 14.2 2.1e-28 98.1 14.2 2.3 2 1 0 2 2 2 1 GDP/GTP exchange factor Sec2p Macoilin PF09726.9 KKK18662.1 - 6.1e-05 21.8 5.2 6.1e-05 21.8 5.2 1.7 2 0 0 2 2 2 1 Macoilin family DUF3584 PF12128.8 KKK18662.1 - 0.00074 17.2 16.6 0.0011 16.7 16.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) TetR_C_1 PF02909.17 KKK18662.1 - 0.094 12.5 0.1 24 4.7 0.0 2.7 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Mer2 PF09074.10 KKK18662.1 - 0.23 11.2 9.7 0.46 10.3 9.7 1.4 1 0 0 1 1 1 0 Mer2 GCN5L1 PF06320.13 KKK18662.1 - 0.38 10.9 14.5 1 9.6 8.1 2.5 2 0 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) DUF1759 PF03564.15 KKK18662.1 - 0.42 10.6 4.4 0.41 10.6 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1759) Exonuc_VII_L PF02601.15 KKK18662.1 - 1.1 8.8 8.8 2.2 7.8 8.8 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit KxDL PF10241.9 KKK18662.1 - 1.3 9.3 7.8 10 6.5 1.2 2.5 2 0 0 2 2 2 0 Uncharacterized conserved protein KfrA_N PF11740.8 KKK18662.1 - 2.2 9.0 17.2 1.7 9.4 0.2 2.7 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term DUF1515 PF07439.11 KKK18662.1 - 3.5 7.7 4.6 14 5.8 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) YjbH PF06082.11 KKK18662.1 - 4.5 6.0 10.9 0.062 12.1 3.8 1.4 2 0 0 2 2 2 0 Exopolysaccharide biosynthesis protein YbjH Golgin_A5 PF09787.9 KKK18662.1 - 5.6 6.3 23.6 0.082 12.4 16.3 1.6 2 0 0 2 2 2 0 Golgin subfamily A member 5 Phage_HK97_TLTM PF06120.11 KKK18662.1 - 6.3 5.9 15.4 34 3.5 15.5 1.9 1 1 0 1 1 1 0 Tail length tape measure protein dsDNA_bind PF01984.20 KKK18663.1 - 5.3e-38 129.7 15.9 6.2e-38 129.5 15.9 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain cwf18 PF08315.12 KKK18663.1 - 0.012 16.3 4.7 0.014 16.1 4.7 1.1 1 0 0 1 1 1 0 cwf18 pre-mRNA splicing factor DUF4615 PF15393.6 KKK18663.1 - 0.015 15.9 0.7 0.015 15.9 0.7 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4615) CdiI_N PF18228.1 KKK18663.1 - 0.071 12.9 0.0 0.1 12.5 0.0 1.2 1 0 0 1 1 1 0 CdiI N-terminal domain AAA_18 PF13238.6 KKK18663.1 - 0.083 13.4 0.9 0.11 13.0 0.4 1.5 1 1 0 1 1 1 0 AAA domain Coq4 PF05019.13 KKK18664.1 - 2.7e-98 327.7 0.0 3.2e-98 327.5 0.0 1.0 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 SET PF00856.28 KKK18665.1 - 5e-19 69.3 0.0 8.1e-19 68.6 0.0 1.3 1 0 0 1 1 1 1 SET domain CDC73_C PF05179.14 KKK18665.1 - 0.073 12.8 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 RNA pol II accessory factor, Cdc73 family, C-terminal ApbA_C PF08546.11 KKK18666.1 - 1.7e-34 118.7 0.1 2.8e-34 118.0 0.1 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 KKK18666.1 - 7e-23 81.0 0.0 2.9e-21 75.7 0.0 2.2 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Sas10_Utp3 PF04000.15 KKK18667.1 - 6e-18 65.2 0.6 6e-18 65.2 0.6 2.3 2 1 0 2 2 2 1 Sas10/Utp3/C1D family Hid1 PF12722.7 KKK18667.1 - 0.0098 14.1 12.6 0.011 14.0 12.6 1.1 1 0 0 1 1 1 1 High-temperature-induced dauer-formation protein CDC45 PF02724.14 KKK18667.1 - 5 5.3 18.9 5.8 5.1 18.9 1.1 1 0 0 1 1 1 0 CDC45-like protein adh_short_C2 PF13561.6 KKK18679.1 - 2.1e-42 145.3 0.0 2.4e-42 145.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KKK18679.1 - 2.1e-34 118.7 0.0 2.9e-34 118.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KKK18679.1 - 4.7e-14 52.7 0.1 5.7e-14 52.4 0.1 1.1 1 0 0 1 1 1 1 KR domain DAO PF01266.24 KKK18679.1 - 0.11 12.0 0.6 0.58 9.7 0.2 1.9 1 1 1 2 2 2 0 FAD dependent oxidoreductase Claudin_2 PF13903.6 KKK18686.1 - 0.03 14.1 2.5 0.15 11.8 0.8 2.4 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction Fungal_trans_2 PF11951.8 KKK18687.1 - 2.8e-09 36.3 0.7 3.7e-09 35.9 0.7 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Velvet PF11754.8 KKK18688.1 - 9.9e-61 205.8 0.2 1.1e-51 176.2 0.0 2.0 1 1 1 2 2 2 2 Velvet factor WD40 PF00400.32 KKK18690.1 - 2.4e-59 195.9 29.7 1.9e-11 44.3 0.1 9.1 8 1 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKK18690.1 - 1.5e-18 66.8 3.6 0.0005 20.3 0.1 5.9 3 2 3 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KKK18690.1 - 9.5e-09 35.4 0.2 0.016 15.1 0.0 3.5 2 2 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KKK18690.1 - 1.1e-06 27.6 5.9 0.19 10.4 0.1 5.7 4 2 2 6 6 6 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KKK18690.1 - 1.1e-05 24.6 1.4 2.7 6.9 0.0 5.0 3 3 2 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein NLE PF08154.12 KKK18690.1 - 1.3e-05 25.6 0.0 2.9e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 NLE (NUC135) domain FAD_binding_9 PF08021.11 KKK18690.1 - 0.0044 17.2 0.0 0.43 10.8 0.0 2.6 2 0 0 2 2 2 1 Siderophore-interacting FAD-binding domain 120_Rick_ant PF12574.8 KKK18690.1 - 0.0059 15.8 0.5 0.1 11.8 0.0 2.3 2 0 0 2 2 2 1 120 KDa Rickettsia surface antigen WD40_like PF17005.5 KKK18690.1 - 0.0089 15.4 0.0 21 4.3 0.0 4.0 4 1 1 5 5 5 0 WD40-like domain DUF4550 PF15084.6 KKK18690.1 - 0.013 15.9 0.0 0.074 13.5 0.0 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4550) MutS_V PF00488.21 KKK18691.1 - 9.7e-62 208.4 0.7 2.2e-61 207.2 0.7 1.6 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KKK18691.1 - 5.7e-32 111.5 3.2 5.7e-32 111.5 3.2 2.2 2 1 0 2 2 2 1 MutS domain III MutS_IV PF05190.18 KKK18691.1 - 4.6e-13 49.3 0.5 1.3e-12 47.9 0.2 2.0 2 0 0 2 2 2 1 MutS family domain IV MutS_II PF05188.17 KKK18691.1 - 1e-10 42.0 0.3 2.9e-10 40.5 0.3 1.8 1 0 0 1 1 1 1 MutS domain II AAA_30 PF13604.6 KKK18691.1 - 0.0013 18.5 0.3 0.009 15.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_27 PF13514.6 KKK18691.1 - 0.038 13.6 0.2 1.4 8.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain DDE_Tnp_1 PF01609.21 KKK18691.1 - 0.055 13.1 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Transposase DDE domain zf-C3HC4_3 PF13920.6 KKK18692.1 - 3e-07 30.2 9.1 3e-07 30.2 9.1 3.3 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KKK18692.1 - 8 6.4 22.9 0.032 14.1 11.2 2.6 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) SWIB PF02201.18 KKK18693.1 - 9e-29 99.2 0.1 1.8e-28 98.2 0.1 1.5 1 0 0 1 1 1 1 SWIB/MDM2 domain DEK_C PF08766.11 KKK18693.1 - 1e-16 60.5 0.1 2e-16 59.6 0.1 1.5 1 0 0 1 1 1 1 DEK C terminal domain Ndc1_Nup PF09531.10 KKK18693.1 - 8.5 4.9 6.5 9.5 4.8 6.5 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup eIF2A PF08662.11 KKK18694.1 - 9.7e-38 130.0 2.3 7.9e-36 123.8 0.8 3.6 3 1 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.22 KKK18694.1 - 2e-07 30.7 0.0 5.2e-07 29.4 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.32 KKK18694.1 - 0.043 14.7 0.1 1.1 10.3 0.1 3.2 2 0 0 2 2 2 0 WD domain, G-beta repeat CAP PF00188.26 KKK18695.1 - 8.6e-19 68.6 4.5 1.8e-18 67.6 4.5 1.6 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Cullin PF00888.22 KKK18695.1 - 0.26 9.8 0.1 0.35 9.4 0.1 1.0 1 0 0 1 1 1 0 Cullin family Sec10 PF07393.11 KKK18696.1 - 1.9e-181 605.1 3.5 2.2e-181 604.9 3.5 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 F-box-like PF12937.7 KKK18696.1 - 2.9e-05 23.9 0.0 9.2e-05 22.3 0.1 1.8 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KKK18696.1 - 0.00099 18.9 0.1 0.0022 17.8 0.1 1.6 1 0 0 1 1 1 1 F-box domain FlhD PF05247.13 KKK18696.1 - 0.026 14.8 0.0 0.07 13.4 0.0 1.7 1 0 0 1 1 1 0 Flagellar transcriptional activator (FlhD) F-box_4 PF15966.5 KKK18696.1 - 0.13 12.2 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 F-box Cytochrom_C1 PF02167.15 KKK18697.1 - 3.9e-92 307.9 0.0 5e-92 307.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.6 KKK18697.1 - 0.021 15.1 0.0 0.047 14.0 0.0 1.6 1 0 0 1 1 1 0 Cytochrome C oxidase, cbb3-type, subunit III AIG2_2 PF13772.6 KKK18698.1 - 0.00094 19.5 0.7 0.0065 16.8 0.2 2.5 2 1 0 2 2 2 1 AIG2-like family DAHP_synth_1 PF00793.20 KKK18699.1 - 2.6e-86 288.9 0.1 9.3e-86 287.1 0.1 1.7 1 1 0 1 1 1 1 DAHP synthetase I family EBP PF05241.12 KKK18700.1 - 9.5e-42 142.5 3.8 1.2e-41 142.2 3.8 1.0 1 0 0 1 1 1 1 Emopamil binding protein DUF3611 PF12263.8 KKK18700.1 - 0.055 13.4 0.6 0.055 13.4 0.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3611) F-box-like PF12937.7 KKK18701.1 - 6.2e-10 38.8 1.5 7.1e-07 29.0 0.2 2.6 2 0 0 2 2 2 2 F-box-like F-box PF00646.33 KKK18701.1 - 2.8e-07 30.2 0.4 0.034 14.1 0.0 2.7 2 0 0 2 2 2 2 F-box domain RSN1_7TM PF02714.15 KKK18702.1 - 5.5e-81 271.9 20.2 9.8e-81 271.1 20.2 1.4 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 KKK18702.1 - 8.7e-46 156.4 0.0 1.3e-45 155.8 0.0 1.2 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 KKK18702.1 - 5.5e-16 58.7 0.3 5.5e-16 58.7 0.3 2.9 3 1 1 4 4 4 1 Late exocytosis, associated with Golgi transport Anoctamin PF04547.12 KKK18702.1 - 3.1 6.5 11.0 0.015 14.2 0.9 2.2 2 1 0 2 2 2 0 Calcium-activated chloride channel hDGE_amylase PF14701.6 KKK18703.1 - 1.2e-178 594.7 0.1 1.6e-178 594.3 0.1 1.1 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain GDE_C PF06202.14 KKK18703.1 - 6.3e-116 387.5 0.0 1.4e-115 386.3 0.0 1.5 2 0 0 2 2 2 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.6 KKK18703.1 - 4.1e-85 285.5 0.0 8.1e-85 284.5 0.0 1.5 1 0 0 1 1 1 1 Central domain of human glycogen debranching enzyme hGDE_N PF14699.6 KKK18703.1 - 1e-30 105.7 0.0 3e-30 104.2 0.0 1.9 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme Alpha-amylase PF00128.24 KKK18703.1 - 0.081 12.5 0.1 0.19 11.2 0.1 1.6 1 0 0 1 1 1 0 Alpha amylase, catalytic domain NAD_Gly3P_dh_N PF01210.23 KKK18704.1 - 8.8e-47 159.0 0.0 1.5e-46 158.3 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.14 KKK18704.1 - 5.6e-43 146.6 0.1 9.4e-43 145.9 0.1 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus F420_oxidored PF03807.17 KKK18704.1 - 0.11 13.1 0.0 20 5.8 0.0 2.5 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent SLX9 PF15341.6 KKK18705.1 - 3e-36 124.7 10.1 4e-36 124.3 10.1 1.2 1 0 0 1 1 1 1 Ribosome biogenesis protein SLX9 Neugrin PF06413.11 KKK18705.1 - 0.016 15.2 5.2 0.28 11.1 1.7 2.1 1 1 1 2 2 2 0 Neugrin HrpJ PF07201.11 KKK18705.1 - 0.077 13.3 2.8 0.16 12.3 2.8 1.5 1 1 0 1 1 1 0 HrpJ-like domain F-box-like PF12937.7 KKK18706.1 - 0.0026 17.6 0.8 0.0058 16.5 0.8 1.6 1 0 0 1 1 1 1 F-box-like LRR_1 PF00560.33 KKK18706.1 - 5.3 8.0 5.4 6.6 7.7 1.6 3.3 2 0 0 2 2 2 0 Leucine Rich Repeat LRR_4 PF12799.7 KKK18706.1 - 5.7 7.5 10.4 0.16 12.4 0.7 3.6 5 0 0 5 5 5 0 Leucine Rich repeats (2 copies) CVNH PF08881.10 KKK18707.1 - 1.6e-19 70.4 0.0 1.8e-19 70.3 0.0 1.0 1 0 0 1 1 1 1 CVNH domain ETX_MTX2 PF03318.13 KKK18707.1 - 0.043 13.6 0.1 0.056 13.2 0.1 1.1 1 0 0 1 1 1 0 Clostridium epsilon toxin ETX/Bacillus mosquitocidal toxin MTX2 Mito_carr PF00153.27 KKK18708.1 - 5.3e-62 205.8 0.1 4.1e-20 71.5 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Ras PF00071.22 KKK18709.1 - 1.3e-63 213.4 0.2 1.6e-63 213.2 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KKK18709.1 - 1.2e-35 122.3 0.2 1.7e-35 121.8 0.2 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKK18709.1 - 3e-13 49.6 0.1 3.9e-13 49.2 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KKK18709.1 - 5.6e-08 32.9 0.1 8.6e-08 32.3 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KKK18709.1 - 8.1e-05 22.6 0.2 0.015 15.2 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 KKK18709.1 - 0.00043 19.9 0.1 0.0022 17.6 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KKK18709.1 - 0.00043 19.7 0.1 0.00071 19.0 0.1 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.6 KKK18709.1 - 0.0026 18.0 0.0 0.02 15.1 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KKK18709.1 - 0.011 16.2 0.0 0.017 15.5 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_14 PF13173.6 KKK18709.1 - 0.013 15.5 0.2 0.041 13.9 0.1 1.9 1 1 0 1 1 1 0 AAA domain SRPRB PF09439.10 KKK18709.1 - 0.017 14.5 0.0 0.03 13.8 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit ABC_tran PF00005.27 KKK18709.1 - 0.021 15.3 0.2 0.028 14.9 0.2 1.5 1 1 0 1 1 1 0 ABC transporter AAA_24 PF13479.6 KKK18709.1 - 0.027 14.2 0.1 0.062 13.0 0.1 1.7 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 KKK18709.1 - 0.059 12.8 0.0 0.17 11.3 0.0 1.7 2 0 0 2 2 2 0 Bacterial TniB protein AAA_21 PF13304.6 KKK18709.1 - 0.1 12.4 0.8 0.17 11.7 0.6 1.5 1 1 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system FeoB_N PF02421.18 KKK18709.1 - 0.1 12.1 0.1 0.23 11.0 0.0 1.6 2 0 0 2 2 2 0 Ferrous iron transport protein B MCM PF00493.23 KKK18709.1 - 0.11 11.6 0.0 0.23 10.5 0.0 1.5 1 1 0 1 1 1 0 MCM P-loop domain AAA_7 PF12775.7 KKK18709.1 - 0.12 11.9 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_5 PF07728.14 KKK18709.1 - 0.14 12.1 0.0 0.31 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Chromo PF00385.24 KKK18710.1 - 3.9e-07 29.9 0.4 3.9e-07 29.9 0.4 2.2 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_2 PF07724.14 KKK18711.1 - 4.2e-39 134.4 0.0 4.4e-38 131.1 0.0 2.6 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.29 KKK18711.1 - 8.2e-15 55.4 0.0 1.6e-14 54.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 KKK18711.1 - 2.9e-08 33.6 0.0 8.1e-08 32.2 0.0 1.7 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 KKK18711.1 - 2.6e-06 27.5 0.0 5.8e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 KKK18711.1 - 7.8e-05 22.4 0.0 0.024 14.3 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain Mg_chelatase PF01078.21 KKK18711.1 - 0.00022 20.7 0.2 0.014 14.8 0.0 3.0 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 KKK18711.1 - 0.00043 20.6 0.5 0.01 16.1 0.5 2.5 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KKK18711.1 - 0.0014 19.0 0.2 0.014 15.8 0.1 2.3 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 KKK18711.1 - 0.0037 17.0 0.1 0.053 13.3 0.0 2.4 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_24 PF13479.6 KKK18711.1 - 0.0049 16.6 0.0 0.0084 15.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KKK18711.1 - 0.0053 16.5 0.0 0.01 15.6 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Sigma54_activ_2 PF14532.6 KKK18711.1 - 0.025 14.7 0.0 0.14 12.3 0.0 2.1 2 1 0 2 2 2 0 Sigma-54 interaction domain AAA_7 PF12775.7 KKK18711.1 - 0.047 13.2 0.0 0.087 12.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region NACHT PF05729.12 KKK18711.1 - 0.051 13.5 0.0 1.7 8.5 0.0 2.3 2 0 0 2 2 2 0 NACHT domain MCM PF00493.23 KKK18711.1 - 0.054 12.6 0.1 0.11 11.6 0.1 1.5 1 0 0 1 1 1 0 MCM P-loop domain RNA_helicase PF00910.22 KKK18711.1 - 0.061 13.7 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.6 KKK18711.1 - 0.061 13.9 0.0 0.14 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 KKK18711.1 - 0.07 13.1 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 KKK18711.1 - 0.086 12.9 0.0 0.19 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 KKK18711.1 - 0.1 12.5 0.0 0.27 11.1 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 KKK18711.1 - 0.17 12.1 0.4 1.5 9.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain PfkB PF00294.24 KKK18713.1 - 9e-19 67.9 0.0 2.5e-18 66.4 0.0 1.6 1 1 0 1 1 1 1 pfkB family carbohydrate kinase Brix PF04427.18 KKK18714.1 - 6e-32 111.3 0.0 7.6e-32 111.0 0.0 1.1 1 0 0 1 1 1 1 Brix domain RPN2_C PF18004.1 KKK18714.1 - 1.1 9.2 4.5 2.1 8.2 4.5 1.5 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain PBP1_TM PF14812.6 KKK18714.1 - 2.5 8.5 8.1 0.11 12.8 2.0 1.9 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal F-box-like PF12937.7 KKK18715.1 - 0.00032 20.5 0.1 0.00032 20.5 0.1 1.8 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KKK18715.1 - 0.0015 18.3 0.5 0.0043 16.9 0.5 1.8 1 0 0 1 1 1 1 F-box domain DUF4817 PF16087.5 KKK18715.1 - 0.014 15.2 1.9 4.3 7.2 0.0 3.1 3 0 0 3 3 3 0 Helix-turn-helix domain (DUF4817) Abp2 PF09441.10 KKK18716.1 - 5.1e-87 290.3 0.1 7.4e-87 289.8 0.1 1.2 1 0 0 1 1 1 1 ARS binding protein 2 Cpn60_TCP1 PF00118.24 KKK18731.1 - 1.1e-143 479.4 13.8 1.3e-143 479.2 13.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family CRM1_repeat PF18777.1 KKK18731.1 - 0.098 12.2 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 Chromosome region maintenance or exportin repeat FlgM PF04316.13 KKK18731.1 - 0.1 13.0 0.7 2.3 8.6 0.0 2.8 2 0 0 2 2 2 0 Anti-sigma-28 factor, FlgM PAD_M PF08527.10 KKK18731.1 - 0.13 12.0 0.5 0.9 9.2 0.1 2.2 2 0 0 2 2 2 0 Protein-arginine deiminase (PAD) middle domain CO_deh_flav_C PF03450.17 KKK18731.1 - 0.19 11.9 1.3 2.5 8.3 0.1 2.8 2 0 0 2 2 2 0 CO dehydrogenase flavoprotein C-terminal domain Pro_isomerase PF00160.21 KKK18732.1 - 9.8e-52 175.4 0.1 1.8e-51 174.5 0.1 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.32 KKK18732.1 - 3.9e-12 46.5 0.0 0.00042 21.1 0.0 4.8 4 0 0 4 4 4 3 WD domain, G-beta repeat Ge1_WD40 PF16529.5 KKK18732.1 - 0.0015 17.6 0.1 0.19 10.7 0.0 3.1 2 1 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein ANAPC4_WD40 PF12894.7 KKK18732.1 - 0.0051 17.1 0.0 1.8 9.0 0.0 2.9 2 1 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Isochorismatase PF00857.20 KKK18733.1 - 8.3e-24 84.7 0.1 9.8e-24 84.5 0.1 1.1 1 0 0 1 1 1 1 Isochorismatase family Ank_2 PF12796.7 KKK18734.1 - 2.6e-34 117.7 0.0 9e-09 35.8 0.0 4.8 3 2 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KKK18734.1 - 1.9e-27 95.3 4.6 0.00014 22.4 0.1 7.3 5 3 2 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 KKK18734.1 - 2.6e-23 79.6 3.8 0.0067 16.9 0.0 9.6 10 0 0 10 10 10 5 Ankyrin repeat Ank_5 PF13857.6 KKK18734.1 - 1.3e-21 76.3 5.3 2.6e-06 27.6 0.1 6.1 5 1 1 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.30 KKK18734.1 - 4e-19 68.1 7.9 0.22 12.0 0.1 9.6 10 0 0 10 10 10 5 Ankyrin repeat DUF2639 PF11121.8 KKK18734.1 - 0.14 12.2 0.0 0.32 11.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2639) Glyco_hydro_76 PF03663.14 KKK18735.1 - 4.3e-152 506.9 20.6 5.1e-152 506.6 20.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 4HB_MCP_1 PF12729.7 KKK18736.1 - 0.019 14.5 7.5 0.03 13.8 7.5 1.2 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction LUC7 PF03194.15 KKK18736.1 - 0.056 13.1 5.7 0.12 12.1 5.7 1.4 1 0 0 1 1 1 0 LUC7 N_terminus AAA_13 PF13166.6 KKK18736.1 - 0.094 11.3 5.5 0.036 12.7 2.3 1.7 2 0 0 2 2 2 0 AAA domain DUF4140 PF13600.6 KKK18736.1 - 0.36 11.3 3.2 8.8 6.8 0.1 3.0 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Cytokin_check_N PF10407.9 KKK18736.1 - 0.44 10.5 1.7 0.45 10.5 0.2 1.8 2 0 0 2 2 2 0 Cdc14 phosphatase binding protein N-terminus DUF4407 PF14362.6 KKK18736.1 - 2.3 7.5 7.2 4.6 6.5 7.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DivIVA PF05103.13 KKK18736.1 - 9.1 6.4 11.4 8.6 6.5 4.6 2.5 2 1 0 2 2 2 0 DivIVA protein SNF2_N PF00176.23 KKK18759.1 - 1.7e-56 191.4 0.6 2.9e-56 190.7 0.0 1.6 2 0 0 2 2 2 1 SNF2 family N-terminal domain zf-C3HC4_2 PF13923.6 KKK18759.1 - 6.9e-09 35.4 8.8 1.9e-08 34.0 8.8 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KKK18759.1 - 3.8e-08 33.1 8.6 9e-08 31.9 8.6 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KKK18759.1 - 9.6e-08 31.8 8.6 2.5e-07 30.4 8.6 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KKK18759.1 - 7.5e-07 29.4 11.2 1.9e-06 28.1 11.2 1.7 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 KKK18759.1 - 9.9e-07 28.5 7.2 2.1e-06 27.5 7.2 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 KKK18759.1 - 1.9e-05 24.6 4.6 2e-05 24.5 3.0 2.0 1 1 0 1 1 1 1 RING-type zinc-finger Helicase_C PF00271.31 KKK18759.1 - 2.3e-05 24.7 0.0 5.1e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-rbx1 PF12678.7 KKK18759.1 - 0.00045 20.5 8.0 0.0014 18.8 8.0 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KKK18759.1 - 0.0012 18.7 8.8 0.0031 17.5 8.8 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KKK18759.1 - 0.032 14.4 7.0 0.084 13.0 7.0 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING DUF1910 PF08928.10 KKK18759.1 - 0.06 13.4 1.0 0.16 12.0 1.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1910) YopE PF03545.13 KKK18759.1 - 0.15 12.3 0.4 4.2 7.6 0.0 2.8 2 0 0 2 2 2 0 Yersinia virulence determinant (YopE) Baculo_IE-1 PF05290.11 KKK18759.1 - 0.18 11.8 2.7 0.23 11.4 0.5 2.3 2 0 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) zf-P11 PF03854.14 KKK18759.1 - 0.77 9.5 8.0 2 8.1 8.0 1.8 1 0 0 1 1 1 0 P-11 zinc finger Zn_ribbon_17 PF17120.5 KKK18759.1 - 0.84 9.3 8.5 1.7 8.3 8.5 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_4 PF14570.6 KKK18759.1 - 1.1 9.1 5.5 3.4 7.6 5.5 1.8 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_10 PF16685.5 KKK18759.1 - 2 8.6 5.7 4.7 7.4 5.7 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 DZR PF12773.7 KKK18759.1 - 9.5 6.3 6.3 27 4.9 3.7 2.5 2 0 0 2 2 2 0 Double zinc ribbon Ecm29 PF13001.7 KKK18760.1 - 1.5e-156 522.0 0.0 5.6e-156 520.1 0.0 2.0 2 0 0 2 2 2 1 Proteasome stabiliser Adaptin_N PF01602.20 KKK18760.1 - 0.016 13.8 0.1 0.97 7.9 0.0 3.2 4 1 0 4 4 4 0 Adaptin N terminal region HEAT_2 PF13646.6 KKK18760.1 - 0.032 14.6 8.1 6.4 7.2 0.6 5.7 6 0 0 6 6 6 0 HEAT repeats PMM PF03332.13 KKK18761.1 - 6e-101 336.8 0.2 8e-101 336.4 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase DnaJ PF00226.31 KKK18761.1 - 7.8e-18 64.4 0.4 2.6e-17 62.7 0.1 2.0 2 0 0 2 2 2 1 DnaJ domain S6PP PF05116.13 KKK18761.1 - 0.005 16.4 0.0 1.7 8.1 0.0 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase_3 PF08282.12 KKK18761.1 - 0.01 15.6 0.0 0.048 13.4 0.0 1.9 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Bacteriocin_IIc PF10439.9 KKK18761.1 - 0.069 13.3 3.6 0.15 12.2 3.6 1.5 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide Gly-zipper_Omp PF13488.6 KKK18761.1 - 2.5 8.2 10.6 5.9 7.0 10.6 1.6 1 0 0 1 1 1 0 Glycine zipper PNGaseA PF12222.8 KKK18762.1 - 4e-188 625.7 0.4 5.9e-188 625.1 0.4 1.2 1 0 0 1 1 1 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A DUF1640 PF07798.11 KKK18762.1 - 2.2e-55 187.4 9.2 3.2e-55 186.9 9.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) P34-Arc PF04045.14 KKK18764.1 - 1.1e-106 355.9 0.1 1.3e-106 355.7 0.1 1.0 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc WD40 PF00400.32 KKK18765.1 - 2.1e-43 145.4 26.4 3.9e-06 27.5 0.4 12.3 12 0 0 12 12 12 8 WD domain, G-beta repeat Utp12 PF04003.12 KKK18765.1 - 7.8e-22 77.6 0.4 1.8e-21 76.4 0.4 1.6 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 KKK18765.1 - 2.1e-18 66.4 2.6 0.0034 17.7 0.0 8.9 6 3 4 11 11 11 6 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KKK18765.1 - 6.3e-09 35.2 2.1 0.036 13.0 0.1 4.8 3 1 0 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 KKK18765.1 - 2.2e-05 23.4 0.8 0.018 13.8 0.0 4.0 2 1 1 3 3 3 1 Nup133 N terminal like Nup160 PF11715.8 KKK18765.1 - 0.00044 19.0 3.1 0.48 9.0 0.0 5.0 6 1 0 6 6 6 1 Nucleoporin Nup120/160 WD40_like PF17005.5 KKK18765.1 - 0.0068 15.8 0.0 15 4.8 0.0 3.7 3 0 0 3 3 3 1 WD40-like domain Frtz PF11768.8 KKK18765.1 - 0.015 13.7 0.0 0.11 10.7 0.0 2.1 2 1 1 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz PALB2_WD40 PF16756.5 KKK18765.1 - 0.11 11.4 0.9 16 4.3 0.2 3.2 3 0 0 3 3 3 0 Partner and localizer of BRCA2 WD40 domain MTP18 PF10558.9 KKK18766.1 - 0.0031 17.5 0.0 0.82 9.6 0.0 2.4 2 0 0 2 2 2 2 Mitochondrial 18 KDa protein (MTP18) F-box PF00646.33 KKK18767.1 - 7.1e-05 22.6 0.0 0.0002 21.1 0.0 1.9 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KKK18767.1 - 8.7e-05 22.3 0.1 0.00021 21.1 0.1 1.7 1 0 0 1 1 1 1 F-box-like Sel1 PF08238.12 KKK18768.1 - 6.9e-13 48.8 10.9 0.0013 19.4 4.5 4.0 4 0 0 4 4 4 3 Sel1 repeat DNA_binding_2 PF13724.6 KKK18768.1 - 5.8 7.4 8.5 2.5 8.5 2.2 3.6 2 0 0 2 2 2 0 DNA-binding domain WLM PF08325.10 KKK18769.1 - 1.4e-68 230.8 0.0 2e-68 230.3 0.0 1.2 1 0 0 1 1 1 1 WLM domain zf-RanBP PF00641.18 KKK18769.1 - 8.9e-05 21.7 21.3 0.00046 19.4 5.0 3.4 3 0 0 3 3 3 3 Zn-finger in Ran binding protein and others DUF45 PF01863.17 KKK18769.1 - 0.0028 17.7 2.4 0.0059 16.7 2.4 1.5 1 0 0 1 1 1 1 Protein of unknown function DUF45 SprT-like PF10263.9 KKK18769.1 - 0.097 12.5 0.9 0.23 11.3 0.9 1.5 1 0 0 1 1 1 0 SprT-like family DZR PF12773.7 KKK18769.1 - 0.39 10.8 12.1 3.4 7.8 1.4 2.3 1 1 2 3 3 3 0 Double zinc ribbon SVIP PF15811.5 KKK18769.1 - 2.1 8.9 8.9 3.8 8.0 0.8 2.6 2 0 0 2 2 2 0 Small VCP/p97-interacting protein HypA PF01155.19 KKK18769.1 - 4.3 7.4 5.0 2.2 8.3 0.2 2.3 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF1776 PF08643.10 KKK18770.1 - 2.5e-108 361.9 0.0 3.1e-108 361.7 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) adh_short PF00106.25 KKK18770.1 - 0.00016 21.2 0.0 0.00045 19.7 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase Glyco_hydro_18 PF00704.28 KKK18771.1 - 1.8e-61 208.6 0.0 2.1e-61 208.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DUF3712 PF12505.8 KKK18772.1 - 3.3e-34 117.8 0.8 1.1e-33 116.1 0.6 2.0 3 0 0 3 3 3 1 Protein of unknown function (DUF3712) Cu-oxidase_3 PF07732.15 KKK18772.1 - 0.01 15.9 0.1 0.025 14.6 0.1 1.7 1 0 0 1 1 1 0 Multicopper oxidase Fcf1 PF04900.12 KKK18773.1 - 7.9e-19 67.9 0.0 3.1e-10 40.3 0.0 2.5 2 0 0 2 2 2 2 Fcf1 SpoIIE PF07228.12 KKK18774.1 - 0.0023 17.9 0.1 0.005 16.8 0.1 1.6 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.21 KKK18774.1 - 0.0097 15.6 0.0 0.014 15.0 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C RRN3 PF05327.11 KKK18775.1 - 3.2e-180 600.4 1.8 9.7e-180 598.8 0.0 1.9 1 1 1 2 2 2 1 RNA polymerase I specific transcription initiation factor RRN3 WD40 PF00400.32 KKK18777.1 - 9.6e-18 64.2 5.4 0.0043 17.9 0.0 5.5 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKK18777.1 - 3.1e-06 27.4 0.4 0.016 15.5 0.1 4.5 4 1 1 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KKK18777.1 - 7.5e-06 24.9 1.4 0.00051 18.8 0.2 2.7 2 1 1 3 3 3 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 KKK18777.1 - 0.022 13.5 0.0 2.8 6.6 0.0 2.8 2 1 1 3 3 3 0 Nup133 N terminal like DUF1615 PF07759.12 KKK18777.1 - 0.13 11.5 1.9 0.21 10.8 1.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1615) Astro_capsid_p PF12226.8 KKK18777.1 - 0.42 9.7 17.1 0.78 8.8 17.1 1.4 1 0 0 1 1 1 0 Turkey astrovirus capsid protein BUD22 PF09073.10 KKK18777.1 - 6.1 6.1 20.7 5.8 6.1 17.8 1.9 2 0 0 2 2 2 0 BUD22 Cmc1 PF08583.10 KKK18778.1 - 2.2e-17 62.8 5.1 2.6e-17 62.6 5.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like ProSAAS PF07259.12 KKK18778.1 - 0.11 12.4 0.1 0.12 12.3 0.1 1.1 1 0 0 1 1 1 0 ProSAAS precursor RNA_Me_trans PF04252.13 KKK18780.1 - 3.2e-83 278.2 0.0 3.6e-83 278.1 0.0 1.0 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase bPH_5 PF10882.8 KKK18780.1 - 0.011 15.8 0.0 5.3 7.2 0.0 2.2 2 0 0 2 2 2 0 Bacterial PH domain Spindle_Spc25 PF08234.12 KKK18781.1 - 6.3e-23 80.8 0.1 2.1e-22 79.1 0.1 2.0 1 0 0 1 1 1 1 Chromosome segregation protein Spc25 CT_C_D PF02682.16 KKK18781.1 - 0.11 12.2 1.6 0.22 11.2 1.6 1.4 1 0 0 1 1 1 0 Carboxyltransferase domain, subdomain C and D Hom_end_hint PF05203.16 KKK18781.1 - 0.15 12.0 0.6 0.18 11.7 0.6 1.1 1 0 0 1 1 1 0 Hom_end-associated Hint DUF4140 PF13600.6 KKK18781.1 - 6.1 7.3 8.9 7.4 7.1 7.6 1.9 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Rrn6 PF10214.9 KKK18782.1 - 3.8e-216 720.5 8.1 4.3e-216 720.3 8.1 1.0 1 0 0 1 1 1 1 RNA polymerase I-specific transcription-initiation factor WD40 PF00400.32 KKK18784.1 - 4.1e-25 87.5 9.8 1.1e-05 26.0 0.5 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKK18784.1 - 7e-12 45.5 1.2 0.26 11.6 0.0 5.1 4 1 1 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 KKK18784.1 - 0.1 11.7 0.1 0.45 9.5 0.1 1.8 2 0 0 2 2 2 0 Coatomer WD associated region TFIIE-A_C PF11521.8 KKK18784.1 - 6 7.2 6.1 3.6 8.0 2.9 2.1 2 0 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha Tcp11 PF05794.13 KKK18785.1 - 2.3e-103 346.7 0.2 2.3e-103 346.7 0.2 3.5 3 1 0 3 3 3 2 T-complex protein 11 zinc_ribbon_6 PF14599.6 KKK18786.1 - 2.8e-24 84.9 0.4 2.8e-24 84.9 0.4 3.5 3 0 0 3 3 2 1 Zinc-ribbon zf-CHY PF05495.12 KKK18786.1 - 4.7e-19 68.7 21.5 4.7e-19 68.7 21.5 3.6 2 1 1 3 3 2 1 CHY zinc finger zf-RING_2 PF13639.6 KKK18786.1 - 6.4e-09 36.0 6.9 6.4e-09 36.0 6.9 5.2 2 1 4 6 6 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 KKK18786.1 - 4.5e-06 26.4 4.6 4.5e-06 26.4 4.6 4.9 4 2 0 4 4 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KKK18786.1 - 9.2e-06 25.4 7.1 9.2e-06 25.4 7.1 5.8 2 1 3 5 5 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KKK18786.1 - 9.4e-06 25.6 5.5 9.4e-06 25.6 5.5 3.6 3 0 0 3 3 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 KKK18786.1 - 0.0011 19.0 6.8 0.0011 19.0 6.8 4.8 5 1 1 6 6 3 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 KKK18786.1 - 0.0085 15.9 6.8 0.0085 15.9 6.8 5.2 4 2 1 5 5 4 1 Prokaryotic RING finger family 4 RNA_pol_3_Rpc31 PF11705.8 KKK18786.1 - 0.9 9.7 15.2 1.7 8.9 15.2 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Nop14 PF04147.12 KKK18786.1 - 0.97 7.6 16.4 1.4 7.1 16.4 1.1 1 0 0 1 1 1 0 Nop14-like family TFIIA PF03153.13 KKK18786.1 - 5.3 6.9 15.0 0.079 12.9 6.5 2.0 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Tim54 PF11711.8 KKK18786.1 - 7.7 5.2 6.1 15 4.3 6.1 1.4 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Endosulfine PF04667.17 KKK18787.1 - 3.3e-29 100.8 0.1 5.2e-29 100.2 0.1 1.3 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region Peptidase_S10 PF00450.22 KKK18788.1 - 1.3e-116 390.5 0.0 1.6e-116 390.2 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Myc_target_1 PF15179.6 KKK18788.1 - 0.2 11.5 0.1 0.36 10.7 0.1 1.3 1 0 0 1 1 1 0 Myc target protein 1 Stevor PF17410.2 KKK18788.1 - 0.24 10.9 0.1 0.58 9.7 0.0 1.6 2 0 0 2 2 2 0 Subtelomeric Variable Open Reading frame Zn_clus PF00172.18 KKK18794.1 - 3.5e-06 27.0 12.6 6e-06 26.3 12.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ASFV_360 PF01671.16 KKK18794.1 - 0.068 12.7 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 African swine fever virus multigene family 360 protein UPF0506 PF11703.8 KKK18794.1 - 1.9 9.0 9.5 8.3 6.9 9.5 2.0 1 1 0 1 1 1 0 UPF0506 Chitin_synth_2 PF03142.15 KKK18817.1 - 2.2e-246 818.6 2.5 3e-246 818.1 2.5 1.2 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.21 KKK18817.1 - 7e-72 242.7 0.0 2.6e-71 240.8 0.0 1.8 1 1 0 1 1 1 1 Myosin head (motor domain) DEK_C PF08766.11 KKK18817.1 - 6.5e-18 64.4 0.2 2.8e-17 62.4 0.3 2.1 2 0 0 2 2 2 1 DEK C terminal domain Cyt-b5 PF00173.28 KKK18817.1 - 1.7e-17 63.3 0.3 2e-14 53.5 0.1 2.7 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_tranf_2_3 PF13641.6 KKK18817.1 - 4.7e-10 39.8 0.1 1.3e-09 38.3 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 KKK18817.1 - 3.8e-09 36.8 4.4 3.8e-09 36.8 4.4 1.9 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 KKK18817.1 - 0.0022 17.8 0.0 0.16 11.8 0.0 2.5 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 KKK18817.1 - 0.0051 16.3 0.0 0.026 14.0 0.0 2.2 3 0 0 3 3 3 1 Glycosyl transferase family 21 RsgA_GTPase PF03193.16 KKK18817.1 - 0.027 14.4 0.2 0.078 12.9 0.0 1.8 2 0 0 2 2 2 0 RsgA GTPase AAA_16 PF13191.6 KKK18817.1 - 0.059 13.7 0.1 0.21 11.9 0.1 1.9 2 0 0 2 2 2 0 AAA ATPase domain Dynactin PF12455.8 KKK18818.1 - 1.4e-99 333.0 8.5 1.4e-99 333.0 8.5 4.1 3 1 0 4 4 4 1 Dynein associated protein CAP_GLY PF01302.25 KKK18818.1 - 1.9e-23 82.3 0.4 3.5e-23 81.4 0.4 1.4 1 0 0 1 1 1 1 CAP-Gly domain DUF3452 PF11934.8 KKK18818.1 - 0.4 10.2 2.3 2.8 7.5 0.6 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3452) HALZ PF02183.18 KKK18818.1 - 0.43 10.8 0.1 0.43 10.8 0.1 7.8 8 1 2 10 10 10 0 Homeobox associated leucine zipper AlgF PF11182.8 KKK18818.1 - 1.1 9.1 3.9 0.38 10.5 0.3 2.1 2 0 0 2 2 2 0 Alginate O-acetyl transferase AlgF UCH PF00443.29 KKK18819.1 - 1.5e-59 201.6 0.0 5.3e-59 199.8 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 KKK18819.1 - 8.7e-15 55.1 0.0 5.3e-14 52.6 0.0 2.4 2 0 0 2 2 2 1 DUSP domain UCH_1 PF13423.6 KKK18819.1 - 2.2e-10 40.7 0.0 0.00039 20.1 0.0 3.4 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase USP7_C2 PF14533.6 KKK18819.1 - 0.0015 18.3 0.4 0.0032 17.2 0.1 1.6 2 0 0 2 2 2 1 Ubiquitin-specific protease C-terminal zf-C2H2 PF00096.26 KKK18843.1 - 0.46 11.0 2.8 1.1 9.9 2.8 1.7 1 0 0 1 1 1 0 Zinc finger, C2H2 type AlaDh_PNT_N PF05222.15 KKK18855.1 - 2.6e-30 105.5 0.0 4.1e-30 104.9 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.21 KKK18855.1 - 1.4e-05 24.5 0.1 0.00018 20.9 0.1 2.4 1 1 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ThiC-associated PF13667.6 KKK18855.1 - 0.11 12.4 0.1 0.21 11.5 0.1 1.4 1 0 0 1 1 1 0 ThiC-associated domain RCC1 PF00415.18 KKK18856.1 - 9.6e-38 128.6 9.3 1.2e-08 35.4 0.2 7.8 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KKK18856.1 - 2.5e-28 97.2 29.4 6e-09 35.5 0.5 7.7 8 0 0 8 8 8 5 Regulator of chromosome condensation (RCC1) repeat SUKH-3 PF14433.6 KKK18856.1 - 0.19 12.2 0.1 36 4.8 0.0 3.3 3 0 0 3 3 3 0 SUKH-3 immunity protein Porin_3 PF01459.22 KKK18856.1 - 2.3 7.6 5.2 17 4.7 5.0 2.1 1 1 1 2 2 2 0 Eukaryotic porin UCH PF00443.29 KKK18857.1 - 4e-35 121.6 0.0 6.8e-31 107.7 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KKK18857.1 - 7.3e-08 32.4 4.1 2e-06 27.6 4.1 2.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Oxysterol_BP PF01237.18 KKK18858.1 - 3.3e-62 210.5 2.9 2e-54 184.9 0.0 2.0 1 1 1 2 2 2 2 Oxysterol-binding protein F_bP_aldolase PF01116.20 KKK18859.1 - 6.9e-92 307.9 0.0 7.7e-92 307.7 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II RSN1_TM PF13967.6 KKK18860.1 - 7.1e-40 136.3 2.2 8.9e-40 136.0 2.2 1.1 1 0 0 1 1 1 1 Late exocytosis, associated with Golgi transport DUF3445 PF11927.8 KKK18862.1 - 0.0063 16.2 0.0 0.0096 15.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) RSN1_7TM PF02714.15 KKK18863.1 - 7.8e-84 281.2 24.7 9.8e-84 280.9 24.7 1.1 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 KKK18863.1 - 1.3e-32 113.5 0.0 2.1e-32 112.8 0.0 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter DUF4078 PF13300.6 KKK18864.1 - 1.9e-25 89.0 16.8 1.9e-25 89.0 16.8 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4078) Homoserine_dh PF00742.19 KKK18865.1 - 6.3e-52 176.0 0.0 8.2e-52 175.6 0.0 1.1 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.16 KKK18865.1 - 3.8e-14 53.3 0.0 7.8e-14 52.3 0.0 1.6 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain DUF3974 PF13120.6 KKK18866.1 - 0.06 13.5 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3974) DnaJ PF00226.31 KKK18866.1 - 0.068 13.3 1.1 0.16 12.1 0.3 1.9 2 0 0 2 2 2 0 DnaJ domain Glyco_transf_4 PF13439.6 KKK18867.1 - 0.1 12.6 0.0 8.2 6.4 0.0 2.5 2 0 0 2 2 2 0 Glycosyltransferase Family 4 HMG_box PF00505.19 KKK18868.1 - 4e-26 91.2 1.1 5.7e-26 90.7 1.1 1.2 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KKK18868.1 - 2.1e-19 69.9 1.5 3.1e-19 69.3 1.5 1.2 1 0 0 1 1 1 1 HMG-box domain Ccdc124 PF06244.12 KKK18868.1 - 0.00054 20.5 1.2 0.0017 18.9 0.0 2.0 1 1 1 2 2 2 1 Coiled-coil domain-containing protein 124 /Oxs1 CHDNT PF08073.12 KKK18868.1 - 0.0078 16.1 0.0 0.012 15.6 0.0 1.2 1 0 0 1 1 1 1 CHDNT (NUC034) domain CENP-H PF05837.12 KKK18869.1 - 2.9e-32 111.4 5.5 2.9e-32 111.4 5.5 2.1 2 0 0 2 2 2 2 Centromere protein H (CENP-H) DivIC PF04977.15 KKK18869.1 - 0.081 12.7 14.1 0.74 9.6 0.6 3.3 3 0 0 3 3 3 0 Septum formation initiator Lge1 PF11488.8 KKK18869.1 - 9.9 6.4 13.3 0.38 11.0 2.5 2.2 2 0 0 2 2 2 0 Transcriptional regulatory protein LGE1 ATG11 PF10377.9 KKK18870.1 - 1.9e-45 154.1 0.0 1.9e-45 154.1 0.0 3.9 3 0 0 3 3 3 1 Autophagy-related protein 11 APG17 PF04108.12 KKK18870.1 - 9.9e-06 24.9 0.7 9.9e-06 24.9 0.7 4.9 2 2 1 3 3 3 2 Autophagy protein Apg17 DUF948 PF06103.11 KKK18870.1 - 2.9 8.2 17.4 8.2 6.8 0.0 6.3 5 0 0 5 5 5 0 Bacterial protein of unknown function (DUF948) Bcr-Abl_Oligo PF09036.10 KKK18870.1 - 7.3 6.7 12.7 0.39 10.7 0.2 4.0 3 0 0 3 3 3 0 Bcr-Abl oncoprotein oligomerisation domain Abhydrolase_3 PF07859.13 KKK18873.1 - 8.6e-42 143.4 0.0 1.5e-40 139.3 0.0 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KKK18873.1 - 1.6e-06 27.2 0.0 1.3e-05 24.2 0.0 2.0 1 1 0 1 1 1 1 Steryl acetyl hydrolase Pterin_4a PF01329.19 KKK18873.1 - 0.03 14.5 0.6 3.8 7.8 0.4 2.4 2 0 0 2 2 2 0 Pterin 4 alpha carbinolamine dehydratase COesterase PF00135.28 KKK18873.1 - 0.06 12.2 0.0 0.2 10.5 0.0 1.7 2 0 0 2 2 2 0 Carboxylesterase family FHA PF00498.26 KKK18874.1 - 5.5e-12 45.9 0.0 1.1e-11 44.9 0.0 1.5 1 0 0 1 1 1 1 FHA domain Glycos_transf_1 PF00534.20 KKK18881.1 - 1e-14 54.5 0.0 2.8e-14 53.0 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KKK18881.1 - 6e-13 49.4 0.0 1.2e-12 48.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 KKK18881.1 - 0.00019 21.7 0.0 0.00043 20.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 DUF3646 PF12362.8 KKK18881.1 - 0.13 12.6 0.0 0.3 11.4 0.0 1.5 1 0 0 1 1 1 0 DNA polymerase III gamma and tau subunits C terminal Rpn3_C PF08375.11 KKK18926.1 - 1.7e-25 89.2 0.6 5.8e-25 87.5 0.6 2.0 1 0 0 1 1 1 1 Proteasome regulatory subunit C-terminal PCI PF01399.27 KKK18926.1 - 1e-19 71.0 0.8 6.4e-19 68.4 0.0 2.5 3 0 0 3 3 3 1 PCI domain SWI-SNF_Ssr4 PF08549.10 KKK18926.1 - 2 6.9 14.2 4 6.0 14.2 1.4 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) polyprenyl_synt PF00348.17 KKK18927.1 - 2.6e-71 239.7 0.0 4.3e-71 239.0 0.0 1.4 1 0 0 1 1 1 1 Polyprenyl synthetase PH_11 PF15413.6 KKK18927.1 - 0.027 14.9 0.0 0.22 11.9 0.0 2.4 2 0 0 2 2 2 0 Pleckstrin homology domain MMM1 PF10296.9 KKK18927.1 - 0.033 13.2 0.0 0.066 12.3 0.0 1.4 1 0 0 1 1 1 0 Maintenance of mitochondrial morphology protein 1 TFIID_20kDa PF03847.13 KKK18928.1 - 1.7e-21 76.5 0.0 3.5e-21 75.5 0.0 1.6 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Histone PF00125.24 KKK18928.1 - 0.0093 16.3 0.0 0.0093 16.3 0.0 2.7 3 0 0 3 3 3 1 Core histone H2A/H2B/H3/H4 DASH_Spc34 PF08657.10 KKK18929.1 - 4.5e-41 141.3 7.4 2.1e-21 76.9 0.1 2.0 1 1 1 2 2 2 2 DASH complex subunit Spc34 DASH_Spc19 PF08287.11 KKK18929.1 - 0.018 15.0 1.2 0.018 15.0 1.2 2.1 2 0 0 2 2 2 0 Spc19 DUF3866 PF12982.7 KKK18929.1 - 0.037 13.1 0.0 0.076 12.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3866) DUF3381 PF11861.8 KKK18929.1 - 0.039 13.8 3.4 0.31 10.8 0.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) REV PF00424.18 KKK18929.1 - 0.081 13.0 0.2 0.18 11.8 0.2 1.6 1 0 0 1 1 1 0 REV protein (anti-repression trans-activator protein) Rotamase PF00639.21 KKK18929.1 - 0.13 13.3 2.1 0.77 10.8 0.1 2.2 2 0 0 2 2 2 0 PPIC-type PPIASE domain TMF_DNA_bd PF12329.8 KKK18929.1 - 0.15 12.1 3.0 7.8 6.6 0.4 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Thg1C PF14413.6 KKK18930.1 - 2.4e-53 179.4 1.3 3.2e-53 179.1 1.3 1.1 1 0 0 1 1 1 1 Thg1 C terminal domain Thg1 PF04446.12 KKK18930.1 - 3.5e-53 178.9 0.0 5.5e-53 178.3 0.0 1.3 1 0 0 1 1 1 1 tRNAHis guanylyltransferase DUF3578 PF12102.8 KKK18930.1 - 0.095 12.3 0.3 0.36 10.4 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3578) Pinin_SDK_memA PF04696.13 KKK18931.1 - 3.9 7.5 42.8 0.075 13.1 12.9 2.1 2 0 0 2 2 2 0 pinin/SDK/memA/ protein conserved region Cmc1 PF08583.10 KKK18932.1 - 8.8e-14 51.3 6.6 2.6e-13 49.8 6.5 1.8 1 1 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like CX9C PF16860.5 KKK18932.1 - 0.0031 17.5 0.1 0.0054 16.7 0.1 1.3 1 0 0 1 1 1 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, DUF3128 PF11326.8 KKK18932.1 - 1.6 9.1 7.2 12 6.3 7.0 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3128) WD40 PF00400.32 KKK18933.1 - 1.1e-16 60.8 0.4 0.00033 21.4 0.0 5.4 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKK18933.1 - 0.00013 22.2 0.0 0.82 10.0 0.0 3.3 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 KKK18933.1 - 0.00054 18.8 0.1 0.67 8.6 0.0 3.0 2 1 0 3 3 3 2 Nup133 N terminal like Nup160 PF11715.8 KKK18933.1 - 0.029 13.0 0.0 4 6.0 0.0 2.8 2 1 1 3 3 3 0 Nucleoporin Nup120/160 TFIID-31kDa PF02291.15 KKK18934.1 - 7.1e-45 152.0 0.0 2.6e-44 150.2 0.0 1.8 1 1 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Spt20 PF12090.8 KKK18934.1 - 3.1 7.4 13.3 0.22 11.1 0.9 2.2 2 0 0 2 2 2 0 Spt20 family Dicty_REP PF05086.12 KKK18934.1 - 4.3 5.2 7.8 9.1 4.1 7.8 1.5 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein SSP160 PF06933.11 KKK18934.1 - 7.3 4.7 25.3 10 4.2 25.3 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 LNS2 PF08235.13 KKK18935.1 - 4.9e-96 320.6 0.0 6.6e-96 320.1 0.0 1.2 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 KKK18935.1 - 8.1e-43 144.5 0.0 1.8e-42 143.4 0.0 1.6 2 0 0 2 2 2 1 lipin, N-terminal conserved region Acid_phosphat_B PF03767.14 KKK18935.1 - 0.0028 17.3 0.0 0.27 10.8 0.0 2.8 3 0 0 3 3 3 1 HAD superfamily, subfamily IIIB (Acid phosphatase) WRNPLPNID PF15017.6 KKK18935.1 - 0.79 10.6 10.8 2.4 9.1 10.8 1.9 1 0 0 1 1 1 0 Putative WW-binding domain and destruction box fn3 PF00041.21 KKK18936.1 - 3.5e-06 27.2 0.0 9.8e-06 25.8 0.0 1.8 1 0 0 1 1 1 1 Fibronectin type III domain APH PF01636.23 KKK18937.1 - 3.8e-09 36.8 0.0 8.8e-09 35.6 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 KKK18937.1 - 0.012 14.5 0.0 0.021 13.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) zf-H2C2_2 PF13465.6 KKK18952.1 - 4.1e-10 39.6 13.1 3.8e-05 23.9 0.4 3.5 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.26 KKK18952.1 - 4e-09 36.4 13.9 2.3e-05 24.6 4.5 2.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KKK18952.1 - 1.1e-06 29.0 10.9 0.0013 19.4 3.2 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 KKK18952.1 - 6.6e-06 26.3 1.3 1.8e-05 24.9 1.3 1.8 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KKK18952.1 - 0.00012 22.0 9.4 0.00012 22.0 2.4 2.6 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KKK18952.1 - 0.00076 19.7 1.8 0.00076 19.7 1.8 2.3 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KKK18952.1 - 0.071 13.5 2.2 0.079 13.3 1.2 1.5 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2HC_2 PF13913.6 KKK18952.1 - 0.11 12.4 4.2 3 7.9 0.4 2.3 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2H2_11 PF16622.5 KKK18952.1 - 0.25 11.1 6.4 5.1 6.9 0.5 2.6 2 0 0 2 2 2 0 zinc-finger C2H2-type Actin_micro PF17003.5 KKK18952.1 - 0.27 10.4 0.3 0.37 9.9 0.3 1.1 1 0 0 1 1 1 0 Putative actin-like family DUF1729 PF08354.10 KKK18959.1 - 1.8e-159 530.3 0.0 2.8e-159 529.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) Acyl_transf_1 PF00698.21 KKK18959.1 - 1.2e-90 304.3 0.0 2.1e-89 300.2 0.0 2.6 3 0 0 3 3 3 1 Acyl transferase domain FAS_meander PF17951.1 KKK18959.1 - 7.4e-52 175.1 0.0 1.9e-51 173.7 0.0 1.8 1 0 0 1 1 1 1 Fatty acid synthase meander beta sheet domain SAT PF16073.5 KKK18959.1 - 2.4e-40 138.8 0.0 1e-39 136.7 0.0 2.2 2 0 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis FAS_N PF17828.1 KKK18959.1 - 4.4e-39 133.4 0.0 3.4e-38 130.6 0.0 2.4 2 0 0 2 2 2 1 N-terminal domain in fatty acid synthase subunit beta MaoC_dehydratas PF01575.19 KKK18959.1 - 7.9e-39 132.0 0.0 2.2e-38 130.6 0.0 1.8 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 KKK18959.1 - 3.5e-22 79.0 0.0 1.1e-21 77.3 0.0 1.9 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase PAS_9 PF13426.7 KKK18966.1 - 4.4e-27 94.4 0.0 4.1e-18 65.6 0.0 3.4 3 0 0 3 3 3 3 PAS domain PAS_3 PF08447.12 KKK18966.1 - 2.4e-20 72.6 0.0 1.1e-09 38.5 0.0 3.7 3 0 0 3 3 3 3 PAS fold PAS PF00989.25 KKK18966.1 - 5.4e-14 52.1 0.0 0.00013 22.0 0.0 3.6 3 0 0 3 3 3 3 PAS fold GATA PF00320.27 KKK18966.1 - 6.4e-14 51.3 5.6 6.4e-14 51.3 5.6 1.9 2 0 0 2 2 2 1 GATA zinc finger PAS_4 PF08448.10 KKK18966.1 - 1.8e-10 41.1 0.0 0.056 13.7 0.0 3.6 3 0 0 3 3 3 3 PAS fold PAS_11 PF14598.6 KKK18966.1 - 2e-08 34.4 0.0 4.1e-05 23.7 0.0 2.8 3 0 0 3 3 3 2 PAS domain PAS_8 PF13188.7 KKK18966.1 - 0.0032 17.5 0.0 0.02 14.9 0.0 2.2 3 0 0 3 3 3 1 PAS domain PAS_2 PF08446.11 KKK18966.1 - 0.012 16.3 0.0 0.46 11.2 0.0 2.6 2 0 0 2 2 2 0 PAS fold Histone PF00125.24 KKK18978.1 - 7.8e-17 61.9 0.0 1.1e-16 61.4 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 KKK18978.1 - 1.1e-11 44.3 0.0 2.4e-11 43.2 0.0 1.6 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 KKK18978.1 - 3.3e-05 24.1 0.0 4.8e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone R3H PF01424.22 KKK18979.1 - 9e-11 41.6 0.0 1.7e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 R3H domain SUZ-C PF12901.7 KKK18979.1 - 9.8e-07 28.7 4.0 2.5e-06 27.4 4.0 1.7 1 0 0 1 1 1 1 SUZ-C motif RRM_1 PF00076.22 KKK18979.1 - 3.9e-06 26.6 0.1 7.2e-06 25.7 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Gp_dh_C PF02800.20 KKK18980.1 - 2.5e-73 244.9 0.1 3.8e-73 244.3 0.1 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 KKK18980.1 - 1.2e-37 128.3 0.0 3.1e-37 127.0 0.0 1.7 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 KKK18980.1 - 0.039 13.3 0.1 0.23 10.8 0.0 1.9 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pho88 PF10032.9 KKK18981.1 - 9.7e-79 262.9 0.0 1.2e-78 262.6 0.0 1.1 1 0 0 1 1 1 1 Phosphate transport (Pho88) Abhydrolase_3 PF07859.13 KKK18983.1 - 7.6e-20 71.7 0.0 9.7e-20 71.3 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KKK18983.1 - 2.9e-19 69.2 0.0 9.4e-19 67.5 0.0 1.7 1 1 0 1 1 1 1 Steryl acetyl hydrolase DUF2974 PF11187.8 KKK18983.1 - 0.0025 17.4 0.0 0.0041 16.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Mog1 PF04603.12 KKK18983.1 - 0.098 13.0 0.0 0.16 12.3 0.0 1.3 1 0 0 1 1 1 0 Ran-interacting Mog1 protein Peptidase_S9 PF00326.21 KKK18983.1 - 0.099 12.1 0.0 2.1 7.8 0.0 2.3 2 0 0 2 2 2 0 Prolyl oligopeptidase family ESSS PF10183.9 KKK18984.1 - 0.0019 18.4 0.2 0.011 15.9 0.0 2.0 1 1 1 2 2 2 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) DctM PF06808.12 KKK18984.1 - 0.029 13.2 0.4 0.044 12.6 0.4 1.2 1 0 0 1 1 1 0 Tripartite ATP-independent periplasmic transporter, DctM component Amnionless PF14828.6 KKK18984.1 - 0.075 11.9 0.0 0.084 11.7 0.0 1.1 1 0 0 1 1 1 0 Amnionless DUF2076 PF09849.9 KKK18984.1 - 0.21 11.6 0.0 0.23 11.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Insulin_TMD PF17870.1 KKK18984.1 - 0.26 11.4 0.9 0.55 10.3 0.5 1.7 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment CENP-F_leu_zip PF10473.9 KKK18985.1 - 0.0066 16.5 2.5 0.0066 16.5 2.5 6.7 3 3 2 5 5 5 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ToxN_toxin PF13958.6 KKK18985.1 - 0.22 11.7 2.8 1 9.6 2.8 2.2 1 0 0 1 1 1 0 Toxin ToxN, type III toxin-antitoxin system Cellulase PF00150.18 KKK18986.1 - 1.1e-06 28.3 1.5 1.8e-06 27.6 0.0 1.9 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) TMEM154 PF15102.6 KKK18986.1 - 0.0032 17.4 0.1 0.011 15.6 0.1 1.8 1 0 0 1 1 1 1 TMEM154 protein family EphA2_TM PF14575.6 KKK18986.1 - 0.0092 16.8 0.8 0.041 14.7 0.0 2.3 2 0 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain DUF5385 PF17359.2 KKK18986.1 - 0.04 13.5 0.1 0.04 13.5 0.1 2.7 3 0 0 3 3 3 0 Family of unknown function (DUF5385) CbiN PF02553.15 KKK18986.1 - 0.07 13.1 0.1 0.23 11.5 0.1 1.9 2 0 0 2 2 2 0 Cobalt transport protein component CbiN ODV-E18 PF10717.9 KKK18986.1 - 0.41 10.6 3.2 1.1 9.2 3.2 1.6 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 Ribonuc_L-PSP PF01042.21 KKK18987.1 - 1.6e-21 76.5 0.0 2e-21 76.2 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP AAA_lid_9 PF17871.1 KKK18987.1 - 0.16 11.9 1.0 0.32 11.0 0.0 1.9 3 0 0 3 3 3 0 AAA lid domain Rax2 PF12768.7 KKK18988.1 - 0.00078 19.0 0.8 0.002 17.7 0.0 1.8 1 1 1 2 2 2 1 Cortical protein marker for cell polarity Dicty_REP PF05086.12 KKK18988.1 - 0.0015 16.7 0.2 0.0018 16.4 0.2 1.1 1 0 0 1 1 1 1 Dictyostelium (Slime Mold) REP protein Podoplanin PF05808.11 KKK18988.1 - 0.0046 17.1 3.4 0.0046 17.1 3.4 1.6 2 0 0 2 2 2 1 Podoplanin Mid2 PF04478.12 KKK18988.1 - 0.0072 16.2 3.2 0.016 15.1 3.1 1.6 1 1 0 1 1 1 1 Mid2 like cell wall stress sensor TMEM154 PF15102.6 KKK18988.1 - 0.011 15.7 2.2 0.022 14.6 2.2 1.6 1 0 0 1 1 1 0 TMEM154 protein family Alpha_GJ PF03229.13 KKK18988.1 - 0.011 16.3 2.6 0.011 16.3 2.6 1.8 2 0 0 2 2 2 0 Alphavirus glycoprotein J Mucin PF01456.17 KKK18988.1 - 0.026 14.5 23.1 0.053 13.5 20.2 2.1 2 0 0 2 2 2 0 Mucin-like glycoprotein Tox-GHH PF15636.6 KKK18988.1 - 0.049 13.6 0.1 0.13 12.3 0.1 1.6 1 0 0 1 1 1 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin SKG6 PF08693.10 KKK18988.1 - 0.05 13.0 0.0 0.05 13.0 0.0 2.4 3 0 0 3 3 2 0 Transmembrane alpha-helix domain SSP160 PF06933.11 KKK18988.1 - 0.054 11.7 16.3 0.094 10.9 16.3 1.4 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 AJAP1_PANP_C PF15298.6 KKK18988.1 - 0.15 12.2 9.8 0.26 11.5 9.8 1.3 1 0 0 1 1 1 0 AJAP1/PANP C-terminus MGC-24 PF05283.11 KKK18988.1 - 0.61 10.5 9.5 0.06 13.8 4.5 1.8 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Gly_transf_sug PF04488.15 KKK18989.1 - 4.7e-11 43.2 0.0 8.2e-11 42.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 KKK18989.1 - 0.00087 18.7 0.0 0.0014 18.1 0.0 1.2 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein MCPVI PF02993.14 KKK18989.1 - 2.7 7.8 5.3 0.79 9.5 2.0 1.7 2 0 0 2 2 2 0 Minor capsid protein VI SNF2_N PF00176.23 KKK18990.1 - 6.3e-66 222.5 0.0 6.7e-64 215.8 0.0 3.0 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KKK18990.1 - 1.1e-16 61.2 0.0 7.1e-16 58.5 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KKK18990.1 - 3.8e-05 23.8 0.0 3.8e-05 23.8 0.0 3.3 2 2 0 2 2 2 1 Type III restriction enzyme, res subunit BUD22 PF09073.10 KKK18990.1 - 6 6.1 58.1 1.9 7.7 30.9 3.3 3 0 0 3 3 3 0 BUD22 Pkinase PF00069.25 KKK18991.1 - 1.7e-59 201.3 0.0 2.4e-59 200.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK18991.1 - 1.8e-30 106.1 0.0 2.4e-30 105.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KKK18991.1 - 7.8e-05 22.1 0.0 0.00014 21.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KKK18991.1 - 0.0029 17.0 0.1 0.0051 16.2 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KKK18991.1 - 0.0053 16.7 1.9 0.012 15.5 0.1 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KKK18991.1 - 0.011 14.5 0.0 0.017 13.9 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Seadorna_VP7 PF07387.11 KKK18991.1 - 0.13 11.3 0.1 0.19 10.8 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Haspin_kinase PF12330.8 KKK18991.1 - 0.23 10.4 0.0 0.39 9.6 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain bZIP_1 PF00170.21 KKK18992.1 - 0.00052 20.1 10.4 0.0016 18.5 10.2 1.9 1 1 1 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 KKK18992.1 - 0.024 14.7 6.2 0.024 14.7 6.2 2.1 2 0 0 2 2 2 0 Basic region leucine zipper eIF-3_zeta PF05091.12 KKK18993.1 - 5.8e-208 692.1 0.0 7.1e-208 691.8 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Pkinase PF00069.25 KKK18994.1 - 1.1e-26 93.9 0.0 1.5e-26 93.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK18994.1 - 5.7e-22 78.2 0.0 8.1e-22 77.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KKK18994.1 - 5.5e-05 22.6 0.0 0.0001 21.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KKK18994.1 - 0.0051 16.2 0.0 0.019 14.3 0.0 1.7 1 1 0 1 1 1 1 Kinase-like RIO1 PF01163.22 KKK18994.1 - 0.041 13.5 0.0 0.061 12.9 0.0 1.2 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 KKK18994.1 - 0.042 13.8 0.0 0.065 13.1 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family WaaY PF06176.11 KKK18994.1 - 0.087 12.4 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) PIP49_C PF12260.8 KKK18994.1 - 0.14 11.7 0.0 0.42 10.2 0.0 1.8 2 0 0 2 2 2 0 Protein-kinase domain of FAM69 Choline_kinase PF01633.20 KKK18994.1 - 0.18 11.3 0.2 0.76 9.3 0.2 1.7 1 1 1 2 2 2 0 Choline/ethanolamine kinase Ribosomal_L33 PF00471.20 KKK18997.1 - 7.9e-06 26.2 0.1 9.6e-06 26.0 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L33 ADH_zinc_N_2 PF13602.6 KKK18998.1 - 2.8e-29 102.9 0.0 4.5e-29 102.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KKK18998.1 - 2.2e-17 63.2 0.0 3.7e-17 62.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KKK18998.1 - 0.00022 21.1 0.2 0.0058 16.5 0.0 2.3 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain PALP PF00291.25 KKK18998.1 - 0.027 13.9 0.0 0.039 13.4 0.0 1.2 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme Sugar_tr PF00083.24 KKK18999.1 - 1.3e-33 116.5 21.9 1.3e-20 73.7 6.4 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KKK18999.1 - 2.6e-18 66.1 38.3 1.3e-10 40.8 11.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily ParA PF10609.9 KKK19000.1 - 9.2e-83 277.5 0.0 1.3e-81 273.6 0.0 2.4 1 1 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 KKK19000.1 - 5.5e-13 49.1 0.0 8e-10 38.9 0.0 2.2 2 0 0 2 2 2 2 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 KKK19000.1 - 1.4e-09 38.1 0.0 6.1e-08 32.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain MipZ PF09140.11 KKK19000.1 - 1.3e-05 24.7 0.0 1.9e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.15 KKK19000.1 - 0.0016 17.7 0.2 0.0059 15.8 0.2 1.8 2 0 0 2 2 2 1 Anion-transporting ATPase AAA_25 PF13481.6 KKK19000.1 - 0.0038 16.8 0.0 0.01 15.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain Fer4_NifH PF00142.18 KKK19000.1 - 0.051 13.0 0.0 0.73 9.2 0.0 2.1 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family CBP_BcsQ PF06564.12 KKK19000.1 - 0.13 11.8 0.2 0.99 8.8 0.1 2.0 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsQ Abhydrolase_3 PF07859.13 KKK19001.1 - 5.7e-32 111.3 0.0 7.2e-25 88.1 0.1 3.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KKK19001.1 - 7.4e-16 58.0 0.0 1.1e-15 57.4 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase TRAUB PF08164.12 KKK19003.1 - 1.6e-28 99.0 0.2 1.6e-28 99.0 0.2 2.5 2 0 0 2 2 2 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.6 KKK19003.1 - 1.9e-27 96.7 2.1 1.9e-27 96.7 2.1 3.5 3 1 0 3 3 3 1 Apoptosis antagonizing transcription factor DUF1257 PF06868.11 KKK19003.1 - 0.029 14.6 0.0 0.06 13.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1257) DUF5383 PF17355.2 KKK19003.1 - 5 7.5 6.8 17 5.8 6.8 1.9 1 0 0 1 1 1 0 Family of unknown function (DUF5383) BCS1_N PF08740.11 KKK19004.1 - 2.6e-48 164.5 0.1 2.6e-48 164.5 0.1 1.7 2 0 0 2 2 2 1 BCS1 N terminal AAA PF00004.29 KKK19004.1 - 2.6e-15 57.0 0.0 5.5e-07 30.1 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 KKK19004.1 - 0.0037 17.1 1.6 0.31 10.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KKK19004.1 - 0.009 16.4 0.1 0.024 15.0 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain DUF815 PF05673.13 KKK19004.1 - 0.009 15.2 0.0 0.018 14.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Oxysterol_BP PF01237.18 KKK19004.1 - 0.035 13.0 2.6 0.058 12.2 2.6 1.3 1 0 0 1 1 1 0 Oxysterol-binding protein ATPase PF06745.13 KKK19004.1 - 0.041 13.2 0.0 0.074 12.4 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_25 PF13481.6 KKK19004.1 - 0.056 13.0 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KKK19004.1 - 0.078 13.5 0.0 0.23 12.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 KKK19004.1 - 0.086 12.8 0.0 0.23 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KKK19004.1 - 0.2 11.4 0.0 0.4 10.4 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain U1snRNP70_N PF12220.8 KKK19004.1 - 0.42 11.3 4.9 1.1 10.0 4.9 1.7 1 0 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RNA_pol_Rpc4 PF05132.14 KKK19004.1 - 5.4 7.4 11.1 75 3.7 0.0 2.3 2 0 0 2 2 2 0 RNA polymerase III RPC4 Phosphodiest PF01663.22 KKK19005.1 - 6.7e-87 292.4 0.1 9.5e-87 291.9 0.1 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 KKK19005.1 - 0.002 17.6 0.2 1.5 8.1 0.0 2.2 1 1 1 2 2 2 2 Sulfatase Metalloenzyme PF01676.18 KKK19005.1 - 0.011 15.1 0.0 0.02 14.3 0.0 1.3 1 0 0 1 1 1 0 Metalloenzyme superfamily PglZ PF08665.12 KKK19005.1 - 0.019 15.1 0.0 0.093 12.8 0.0 2.0 2 0 0 2 2 2 0 PglZ domain DUF229 PF02995.17 KKK19005.1 - 0.19 10.3 0.0 0.28 9.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF229) CBFB_NFYA PF02045.15 KKK19008.1 - 1.5e-28 99.2 4.6 3.2e-28 98.1 4.6 1.6 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B Hus1 PF04005.12 KKK19008.1 - 0.05 12.7 0.0 0.1 11.7 0.0 1.4 1 0 0 1 1 1 0 Hus1-like protein TFIIA PF03153.13 KKK19008.1 - 0.16 11.9 30.7 0.21 11.6 30.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Kinesin PF00225.23 KKK19009.1 - 1.5e-111 372.5 0.0 2.4e-111 371.9 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain DUF3694 PF12473.8 KKK19009.1 - 3.4e-45 154.5 0.2 1.6e-44 152.3 0.1 2.2 2 0 0 2 2 2 1 Kinesin protein Kinesin_assoc PF16183.5 KKK19009.1 - 3.5e-36 125.0 13.4 1.9e-30 106.4 0.6 3.4 3 1 1 4 4 4 2 Kinesin-associated Microtub_bd PF16796.5 KKK19009.1 - 1.9e-25 89.5 0.0 5.1e-25 88.1 0.0 1.8 1 0 0 1 1 1 1 Microtubule binding KIF1B PF12423.8 KKK19009.1 - 3e-07 30.8 0.1 3e-07 30.8 0.1 2.5 2 0 0 2 2 2 1 Kinesin protein 1B PH PF00169.29 KKK19009.1 - 9.4e-07 29.3 0.0 2.3e-06 28.0 0.0 1.7 1 0 0 1 1 1 1 PH domain FHA PF00498.26 KKK19009.1 - 0.00012 22.3 0.6 0.00091 19.5 0.0 2.8 3 0 0 3 3 3 1 FHA domain Nas2_N PF18265.1 KKK19009.1 - 0.43 10.5 2.2 0.77 9.7 0.1 2.6 2 0 0 2 2 2 0 Nas2 N_terminal domain UPF0242 PF06785.11 KKK19009.1 - 1.8 8.6 9.8 6.4 6.8 0.5 2.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Glyco_transf_90 PF05686.12 KKK19010.1 - 2.3e-28 99.2 0.0 3.6e-28 98.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 90 Glyco_trans_1_2 PF13524.6 KKK19010.1 - 0.001 19.4 0.0 0.0019 18.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_hydro_43 PF04616.14 KKK19011.1 - 4.7e-34 118.0 0.0 6e-34 117.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Trypan_PARP PF05887.11 KKK19012.1 - 0.0089 16.0 2.2 0.0089 16.0 2.2 2.6 2 0 0 2 2 2 1 Procyclic acidic repetitive protein (PARP) CPSF100_C PF13299.6 KKK19012.1 - 0.2 11.8 2.2 0.39 10.9 2.2 1.4 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DUF3546 PF12066.8 KKK19013.1 - 2.9e-32 111.1 1.0 2.9e-32 111.1 1.0 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF3546) ARS2 PF04959.13 KKK19013.1 - 8.7e-14 52.4 0.0 3.1e-13 50.5 0.0 2.0 1 0 0 1 1 1 1 Arsenite-resistance protein 2 DUF4187 PF13821.6 KKK19013.1 - 9.5e-13 47.7 0.9 2.1e-12 46.6 0.9 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) ER_lumen_recept PF00810.18 KKK19029.1 - 5.6e-43 147.3 4.6 9.1e-43 146.6 4.6 1.3 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.14 KKK19029.1 - 0.0079 15.9 0.0 0.0079 15.9 0.0 3.5 4 0 0 4 4 4 2 PQ loop repeat Phage_holin_1 PF04531.13 KKK19029.1 - 0.75 10.4 2.8 2.2 8.9 0.9 2.4 2 0 0 2 2 2 0 Bacteriophage holin eRF1_1 PF03463.15 KKK19031.1 - 2.3e-48 163.4 0.0 3.5e-48 162.8 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_2 PF03464.15 KKK19031.1 - 4.3e-13 49.7 0.1 1.5e-10 41.5 0.0 2.3 1 1 1 2 2 2 2 eRF1 domain 2 eRF1_3 PF03465.15 KKK19031.1 - 4.2e-11 43.3 0.0 8.5e-11 42.3 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 3 LptE PF04390.12 KKK19031.1 - 0.019 15.6 0.1 0.82 10.4 0.0 2.7 2 1 0 2 2 2 0 Lipopolysaccharide-assembly TerB_C PF15615.6 KKK19032.1 - 4.8 7.5 10.1 0.54 10.5 4.8 2.0 2 0 0 2 2 2 0 TerB-C domain DUF4551 PF15087.6 KKK19032.1 - 5.4 5.7 7.3 6.5 5.5 7.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) LRR_6 PF13516.6 KKK19033.1 - 5.2e-11 41.7 6.1 0.59 10.3 0.0 7.1 9 0 0 9 9 9 4 Leucine Rich repeat F-box-like PF12937.7 KKK19033.1 - 3.4e-10 39.7 0.0 1.1e-09 38.0 0.0 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KKK19033.1 - 2.5e-09 36.8 0.6 1.4e-08 34.4 0.1 2.6 3 0 0 3 3 3 1 F-box domain LRR_4 PF12799.7 KKK19033.1 - 4.8e-06 26.8 5.1 0.0022 18.4 0.0 5.2 4 2 2 6 6 6 1 Leucine Rich repeats (2 copies) Sugar_tr PF00083.24 KKK19033.1 - 0.0061 15.5 0.1 0.0091 14.9 0.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter LRR_1 PF00560.33 KKK19033.1 - 0.075 13.6 9.5 47 5.1 0.0 6.0 7 1 0 7 7 7 0 Leucine Rich Repeat Yippee-Mis18 PF03226.14 KKK19034.1 - 1e-18 67.5 1.8 1.1e-18 67.3 1.8 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RIG-I_C-RD PF11648.8 KKK19034.1 - 0.0032 17.7 1.1 0.0045 17.2 1.1 1.3 1 0 0 1 1 1 1 C-terminal domain of RIG-I DUF2039 PF10217.9 KKK19034.1 - 0.0075 16.6 2.4 0.017 15.4 0.4 2.1 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2039) HNH_5 PF14279.6 KKK19034.1 - 0.038 13.8 0.3 1.4 8.9 0.0 2.3 2 0 0 2 2 2 0 HNH endonuclease Evr1_Alr PF04777.13 KKK19034.1 - 0.075 13.5 1.2 2.1 8.9 0.1 2.1 1 1 1 2 2 2 0 Erv1 / Alr family zf-RRPl_C4 PF17026.5 KKK19034.1 - 0.088 12.9 4.5 0.26 11.4 1.3 2.3 1 1 1 2 2 2 0 Putative ribonucleoprotein zinc-finger pf C4 type Endonuclease_7 PF02945.15 KKK19034.1 - 0.56 10.2 4.2 0.24 11.3 1.0 2.2 1 1 1 2 2 2 0 Recombination endonuclease VII Pkinase PF00069.25 KKK19035.1 - 2.8e-57 194.1 0.0 4.1e-57 193.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK19035.1 - 3.5e-20 72.4 0.0 5.5e-20 71.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KKK19035.1 - 2.1e-05 24.0 0.0 4.7e-05 22.8 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 KKK19035.1 - 8.1e-05 22.1 0.1 0.00014 21.3 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KKK19035.1 - 8.5e-05 22.6 0.1 0.015 15.3 0.1 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KKK19035.1 - 0.00039 19.5 0.0 0.00064 18.8 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 KKK19035.1 - 0.00055 18.8 0.0 0.00087 18.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 KKK19035.1 - 0.0016 18.1 0.0 0.0039 16.8 0.0 1.6 1 0 0 1 1 1 1 RIO1 family RabGAP-TBC PF00566.18 KKK19037.1 - 3.6e-33 115.0 1.7 3.6e-33 115.0 1.7 1.5 2 0 0 2 2 2 1 Rab-GTPase-TBC domain SWI-SNF_Ssr4 PF08549.10 KKK19037.1 - 0.0092 14.7 2.9 0.017 13.8 2.9 1.3 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1750) Serine_rich PF08824.10 KKK19037.1 - 0.027 14.5 0.7 0.073 13.1 0.7 1.7 1 0 0 1 1 1 0 Serine rich protein interaction domain Gp-FAR-1 PF05823.12 KKK19037.1 - 0.062 13.7 0.7 0.12 12.8 0.7 1.4 1 0 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Ribosomal_S5 PF00333.20 KKK19037.1 - 0.13 12.3 0.2 0.28 11.2 0.2 1.6 1 0 0 1 1 1 0 Ribosomal protein S5, N-terminal domain Dioxygenase_C PF00775.21 KKK19038.1 - 1.6e-49 167.8 0.0 2.1e-49 167.4 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 KKK19038.1 - 4.5e-28 96.9 0.2 7.3e-28 96.2 0.2 1.3 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.6 KKK19038.1 - 1.4e-05 25.3 0.0 2.8e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain CarbopepD_reg_2 PF13715.6 KKK19038.1 - 0.017 15.1 0.0 2.1 8.4 0.0 3.1 3 0 0 3 3 3 0 CarboxypepD_reg-like domain Lipase_C PF18067.1 KKK19038.1 - 0.056 14.0 0.0 0.11 13.1 0.0 1.5 1 0 0 1 1 1 0 Lipase C-terminal domain Abhydrolase_1 PF00561.20 KKK19039.1 - 1.1e-21 77.7 0.1 5.2e-19 68.9 0.1 2.0 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KKK19039.1 - 2.2e-18 66.4 0.1 3.9e-18 65.6 0.1 1.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KKK19039.1 - 2.8e-16 60.8 0.0 4e-16 60.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.14 KKK19039.1 - 1.2e-08 34.0 0.0 2e-08 33.3 0.0 1.3 1 1 0 1 1 1 1 Ndr family BAAT_C PF08840.11 KKK19039.1 - 5e-06 26.6 0.1 1.2e-05 25.3 0.1 1.5 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S9 PF00326.21 KKK19039.1 - 7.9e-06 25.5 0.0 0.0014 18.1 0.0 2.2 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 KKK19039.1 - 6.6e-05 22.8 0.2 0.12 12.1 0.1 3.0 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase DLH PF01738.18 KKK19039.1 - 0.00021 20.9 0.1 0.47 10.0 0.1 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family Ser_hydrolase PF06821.13 KKK19039.1 - 0.00075 19.4 0.2 0.01 15.7 0.2 2.1 1 1 0 1 1 1 1 Serine hydrolase Abhydrolase_5 PF12695.7 KKK19039.1 - 0.0027 17.5 0.1 0.0076 16.0 0.1 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family PGAP1 PF07819.13 KKK19039.1 - 0.0035 17.1 1.2 0.0095 15.7 0.3 2.0 2 0 0 2 2 2 1 PGAP1-like protein Thioesterase PF00975.20 KKK19039.1 - 0.0064 16.6 0.0 0.0072 16.5 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Esterase PF00756.20 KKK19039.1 - 0.0069 16.1 0.4 0.014 15.1 0.4 1.6 1 1 0 1 1 1 1 Putative esterase DUF676 PF05057.14 KKK19039.1 - 0.0091 15.5 0.1 0.03 13.8 0.0 1.8 1 1 1 2 2 2 1 Putative serine esterase (DUF676) Lipase PF00151.19 KKK19039.1 - 0.021 14.1 0.1 0.045 13.0 0.1 1.5 2 0 0 2 2 2 0 Lipase DUF915 PF06028.11 KKK19039.1 - 0.022 14.1 0.0 0.12 11.7 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) UPF0227 PF05728.12 KKK19039.1 - 0.027 14.4 0.3 0.05 13.5 0.2 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0227) PAF-AH_p_II PF03403.13 KKK19039.1 - 0.047 12.2 0.2 1.1 7.6 0.0 2.3 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II Lipase_3 PF01764.25 KKK19039.1 - 0.15 11.9 0.5 0.37 10.7 0.4 1.6 1 1 0 1 1 1 0 Lipase (class 3) Efg1 PF10153.9 KKK19040.1 - 2.7e-32 111.5 9.8 2.7e-32 111.5 9.8 1.8 2 0 0 2 2 2 1 rRNA-processing protein Efg1 DUF2489 PF10675.9 KKK19040.1 - 0.043 13.7 0.5 0.043 13.7 0.5 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2489) Pox_A_type_inc PF04508.12 KKK19040.1 - 0.12 12.2 1.2 0.47 10.4 1.2 2.1 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat TMF_TATA_bd PF12325.8 KKK19040.1 - 0.29 11.4 5.7 4.9 7.4 0.8 2.9 3 0 0 3 3 3 0 TATA element modulatory factor 1 TATA binding PTS_2-RNA PF01885.16 KKK19041.1 - 9.3e-66 221.3 0.0 1.5e-65 220.7 0.0 1.3 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family zinc_ribbon_16 PF17034.5 KKK19041.1 - 4.8e-17 62.3 3.1 1.1e-16 61.2 3.1 1.6 1 0 0 1 1 1 1 Zinc-ribbon like family WD40 PF00400.32 KKK19041.1 - 0.0042 17.9 0.1 8.8 7.4 0.1 4.5 3 0 0 3 3 3 1 WD domain, G-beta repeat Hexokinase_1 PF00349.21 KKK19041.1 - 0.042 13.7 0.1 0.092 12.6 0.1 1.5 1 0 0 1 1 1 0 Hexokinase Zn_ribbon_17 PF17120.5 KKK19041.1 - 0.054 13.1 4.6 0.028 14.0 1.3 2.2 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type Na_H_antiport_3 PF07399.11 KKK19041.1 - 0.26 10.1 0.0 0.39 9.6 0.0 1.2 1 0 0 1 1 1 0 Putative Na+/H+ antiporter zf-rbx1 PF12678.7 KKK19041.1 - 4.1 7.8 5.5 1.8 8.9 2.3 2.1 2 0 0 2 2 2 0 RING-H2 zinc finger domain Chorismate_bind PF00425.18 KKK19052.1 - 1e-90 303.8 0.0 1.5e-90 303.2 0.0 1.3 1 0 0 1 1 1 1 chorismate binding enzyme Anth_synt_I_N PF04715.13 KKK19052.1 - 5.5e-27 94.7 0.0 2.9e-24 85.9 0.0 3.2 3 1 0 3 3 3 2 Anthranilate synthase component I, N terminal region IL2 PF00715.17 KKK19053.1 - 0.031 14.2 0.4 0.056 13.4 0.4 1.5 1 0 0 1 1 1 0 Interleukin 2 DUF5631 PF18645.1 KKK19053.1 - 0.14 12.5 0.1 0.38 11.2 0.0 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5631) Jnk-SapK_ap_N PF09744.9 KKK19053.1 - 3.6 7.8 9.0 1.7 8.9 6.1 1.8 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 Nuc_sug_transp PF04142.15 KKK19061.1 - 1.4e-25 90.1 3.2 1.4e-25 90.1 3.2 1.6 1 1 1 2 2 2 1 Nucleotide-sugar transporter UAA PF08449.11 KKK19061.1 - 4e-05 23.0 2.1 4e-05 23.0 2.1 2.3 1 1 1 2 2 2 1 UAA transporter family CRT-like PF08627.10 KKK19061.1 - 0.00013 21.0 4.4 0.00013 21.0 4.4 1.7 2 0 0 2 2 2 1 CRT-like, chloroquine-resistance transporter-like EmrE PF13536.6 KKK19061.1 - 0.001 18.8 0.7 0.001 18.8 0.7 2.2 1 1 1 2 2 2 1 Putative multidrug resistance efflux transporter EamA PF00892.20 KKK19061.1 - 0.56 10.4 26.0 0.21 11.8 4.6 3.2 2 2 0 2 2 2 0 EamA-like transporter family Antimicrobial10 PF08105.11 KKK19061.1 - 2.5 8.3 4.1 1.9 8.7 0.3 2.7 3 0 0 3 3 3 0 Metchnikowin family Phage_holin_5_2 PF16079.5 KKK19061.1 - 7.4 7.0 10.3 0.87 10.0 0.8 3.0 2 1 1 3 3 3 0 Phage holin family Hol44, in holin superfamily V LapA_dom PF06305.11 KKK19061.1 - 9.4 6.1 12.4 1.4 8.8 3.2 3.5 2 2 1 3 3 3 0 Lipopolysaccharide assembly protein A domain MFS_1 PF07690.16 KKK19062.1 - 5.2e-36 124.3 53.9 1.5e-34 119.5 32.1 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2614 PF11023.8 KKK19062.1 - 6.7 6.8 7.7 1.7 8.8 0.3 3.1 3 0 0 3 3 3 0 Zinc-ribbon containing domain PI-PLC-X PF00388.19 KKK19063.1 - 2.8e-05 23.7 0.0 4.4e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain DUF4043 PF13252.6 KKK19063.1 - 0.14 11.2 0.0 0.23 10.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4043) Fungal_trans PF04082.18 KKK19064.1 - 1.5e-15 57.0 0.0 2.6e-15 56.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK19064.1 - 1.8e-08 34.4 10.1 3.5e-08 33.4 10.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PLDc_2 PF13091.6 KKK19065.1 - 6.8e-21 74.5 0.2 3.1e-11 43.3 0.0 2.4 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 KKK19065.1 - 0.002 18.2 0.1 0.29 11.4 0.1 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif Regulator_TrmB PF11495.8 KKK19065.1 - 0.032 13.4 0.0 0.32 10.1 0.0 2.1 2 0 0 2 2 2 0 Archaeal transcriptional regulator TrmB Transp_cyt_pur PF02133.15 KKK19066.1 - 2.2e-25 89.4 30.6 5.3e-25 88.1 30.6 1.5 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Nramp PF01566.18 KKK19066.1 - 4.8e-06 25.8 18.4 0.00019 20.5 11.6 2.4 2 0 0 2 2 2 2 Natural resistance-associated macrophage protein VWA_2 PF13519.6 KKK19067.1 - 0.00062 20.4 0.0 0.0017 18.9 0.0 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 KKK19067.1 - 0.038 14.2 0.0 0.16 12.2 0.0 2.1 1 1 0 1 1 1 0 von Willebrand factor type A domain His_Phos_2 PF00328.22 KKK19068.1 - 7.2e-05 22.3 0.0 0.29 10.5 0.0 2.2 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) zf-HC5HC2H_2 PF13832.6 KKK19073.1 - 3e-22 78.9 0.6 3e-22 78.9 0.6 4.3 5 0 0 5 5 5 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 KKK19073.1 - 3.5e-20 72.0 1.8 3.5e-20 72.0 1.8 4.8 5 0 0 5 5 5 1 PHD-like zinc-binding domain BAH PF01426.18 KKK19073.1 - 3.1e-12 46.4 0.1 7.3e-12 45.2 0.1 1.6 1 0 0 1 1 1 1 BAH domain PHD PF00628.29 KKK19073.1 - 5.6e-11 42.2 20.3 5.5e-07 29.4 5.7 5.8 7 0 0 7 7 7 3 PHD-finger PHD_2 PF13831.6 KKK19073.1 - 1.6e-09 37.1 5.0 1.6e-09 37.1 5.0 4.8 5 0 0 5 5 5 1 PHD-finger Myb_DNA-binding PF00249.31 KKK19073.1 - 2e-05 24.7 0.1 6.8e-05 23.0 0.1 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain FYVE_2 PF02318.16 KKK19073.1 - 0.0037 17.5 1.8 0.0037 17.5 1.8 4.6 5 0 0 5 5 5 2 FYVE-type zinc finger C1_1 PF00130.22 KKK19073.1 - 0.0048 16.7 2.1 0.0048 16.7 2.1 6.4 7 1 1 8 8 8 2 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.16 KKK19073.1 - 0.049 14.0 0.5 0.049 14.0 0.5 6.6 8 0 0 8 8 8 0 C1 domain ELM2 PF01448.24 KKK19073.1 - 2.3 9.0 5.9 13 6.7 0.5 4.1 3 2 0 3 3 3 0 ELM2 domain GATase_4 PF13230.6 KKK19076.1 - 3.3e-13 49.2 0.0 5.5e-12 45.2 0.0 2.1 1 1 0 2 2 2 1 Glutamine amidotransferases class-II GATase_6 PF13522.6 KKK19076.1 - 8.4e-09 35.7 0.0 1.5e-08 35.0 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain PIG-Y PF15159.6 KKK19077.1 - 5e-23 81.8 8.7 8e-23 81.2 8.7 1.3 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y Paxillin PF03535.13 KKK19077.1 - 0.013 15.4 5.3 0.07 13.0 0.3 2.2 2 0 0 2 2 2 0 Paxillin family DUF1218 PF06749.12 KKK19077.1 - 0.029 14.9 1.7 4.1 8.0 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1218) K_channel_TID PF07941.11 KKK19077.1 - 2.1 8.8 10.7 0.068 13.6 3.2 2.3 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain RRM_1 PF00076.22 KKK19078.1 - 1.8e-40 136.6 0.0 1.8e-21 75.7 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KKK19078.1 - 2.9e-05 23.8 0.0 0.0019 18.0 0.0 2.3 2 1 0 2 2 2 1 Occluded RNA-recognition motif Nup35_RRM PF05172.13 KKK19078.1 - 0.0089 16.0 0.0 1.8 8.6 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 KKK19078.1 - 0.014 15.0 0.0 0.87 9.2 0.0 2.2 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KKK19078.1 - 0.052 13.7 0.0 0.41 10.8 0.0 2.3 2 1 0 2 2 2 0 RNA recognition motif NACHT_N PF17100.5 KKK19079.1 - 2.4e-33 115.9 1.1 5.7e-32 111.4 0.0 2.0 2 0 0 2 2 2 1 N-terminal domain of NWD NACHT-NTPase Rab5-bind PF09311.11 KKK19079.1 - 6e-05 22.6 3.9 9.6e-05 21.9 3.9 1.3 1 0 0 1 1 1 1 Rabaptin-like protein DUF5344 PF17279.2 KKK19079.1 - 0.073 13.7 1.3 0.13 12.8 1.3 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5344) DUF4665 PF15679.5 KKK19079.1 - 0.13 12.9 1.9 0.22 12.2 1.2 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4665) DUF4709 PF15821.5 KKK19079.1 - 0.19 12.0 4.6 0.4 11.0 3.4 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4709) Nsp1_C PF05064.13 KKK19079.1 - 0.21 11.4 5.2 0.6 9.9 5.2 1.8 1 1 0 1 1 1 0 Nsp1-like C-terminal region DUF4681 PF15732.5 KKK19079.1 - 0.24 11.7 5.1 0.25 11.6 3.6 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4681) Cep57_MT_bd PF06657.13 KKK19079.1 - 0.71 10.4 4.9 0.66 10.5 0.4 2.4 1 1 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Dynamin_N PF00350.23 KKK19080.1 - 1.6e-44 151.9 0.0 3.1e-44 151.0 0.0 1.5 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 KKK19080.1 - 5.4e-15 55.4 0.0 4.8e-12 45.7 0.0 2.4 2 0 0 2 2 2 2 Dynamin central region MMR_HSR1 PF01926.23 KKK19080.1 - 4.5e-05 23.5 0.0 0.00012 22.1 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase Zeta_toxin PF06414.12 KKK19080.1 - 0.015 14.6 0.1 2.3 7.4 0.0 2.9 3 0 0 3 3 3 0 Zeta toxin AAA_16 PF13191.6 KKK19080.1 - 0.023 15.1 0.5 0.24 11.8 0.0 2.8 3 1 0 3 3 3 0 AAA ATPase domain AAA_15 PF13175.6 KKK19080.1 - 0.029 14.1 0.4 0.21 11.2 0.1 2.3 2 1 0 2 2 2 0 AAA ATPase domain phiKZ_IP PF12699.7 KKK19080.1 - 0.05 12.7 0.2 0.13 11.4 0.0 1.7 2 0 0 2 2 2 0 phiKZ-like phage internal head proteins AAA_21 PF13304.6 KKK19080.1 - 0.059 13.2 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system Pyr_redox_2 PF07992.14 KKK19081.1 - 6.6e-52 176.6 0.1 8.3e-52 176.2 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KKK19081.1 - 1.9e-10 41.2 0.0 4.6e-09 36.7 0.1 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KKK19081.1 - 0.00016 21.0 0.1 0.098 11.9 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 KKK19081.1 - 0.3 11.5 4.3 7.2 7.1 0.0 3.6 3 1 0 3 3 3 0 Putative NAD(P)-binding 4HBT_2 PF13279.6 KKK19086.1 - 7.3e-27 94.3 0.1 1.3e-26 93.5 0.1 1.4 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.22 KKK19086.1 - 2.4e-05 24.6 0.0 4.8e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Thioesterase superfamily GCD14 PF08704.10 KKK19087.1 - 4.5e-06 26.5 0.3 0.015 15.0 0.0 2.6 3 0 0 3 3 3 2 tRNA methyltransferase complex GCD14 subunit GCD14_N PF14801.6 KKK19087.1 - 0.0001 22.0 0.3 0.00019 21.2 0.3 1.4 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit N-term Methyltransf_25 PF13649.6 KKK19087.1 - 0.1 13.3 0.1 20 6.0 0.0 2.5 2 0 0 2 2 2 0 Methyltransferase domain HAD PF12710.7 KKK19088.1 - 1.7e-22 80.7 0.0 2.2e-22 80.4 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase UMPH-1 PF05822.12 KKK19088.1 - 0.057 12.9 0.0 0.2 11.2 0.0 1.8 1 1 0 1 1 1 0 Pyrimidine 5'-nucleotidase (UMPH-1) DUF1574 PF07611.11 KKK19088.1 - 0.068 12.5 0.0 0.088 12.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1574) Metallophos PF00149.28 KKK19089.1 - 4.7e-17 63.2 0.4 7.8e-17 62.5 0.4 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KKK19089.1 - 0.0001 22.5 0.0 0.0014 18.9 0.0 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain FMN_dh PF01070.18 KKK19090.1 - 5.7e-121 403.8 0.0 6.6e-121 403.6 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 KKK19090.1 - 3e-06 26.5 0.5 7.1e-05 22.0 0.1 2.1 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 KKK19090.1 - 0.00021 20.6 0.1 0.00032 19.9 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase DHO_dh PF01180.21 KKK19090.1 - 0.021 14.1 0.0 0.032 13.4 0.0 1.3 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase His_biosynth PF00977.21 KKK19090.1 - 0.11 11.9 0.0 0.48 9.9 0.0 2.0 1 1 0 1 1 1 0 Histidine biosynthesis protein Fungal_trans_2 PF11951.8 KKK19091.1 - 4e-61 207.0 5.1 5.5e-61 206.5 5.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK19091.1 - 7.9e-10 38.7 6.0 1.7e-09 37.6 6.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldolase_II PF00596.21 KKK19092.1 - 2.6e-49 167.7 0.2 3.2e-49 167.4 0.2 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Aldedh PF00171.22 KKK19093.1 - 6.5e-125 417.2 4.1 7.3e-125 417.1 4.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family HD_3 PF13023.6 KKK19095.1 - 1.4e-47 161.7 0.0 1.9e-47 161.3 0.0 1.1 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 KKK19095.1 - 1e-10 41.7 0.1 1.3e-10 41.3 0.1 1.2 1 0 0 1 1 1 1 HD containing hydrolase-like enzyme Il2rg PF15874.5 KKK19095.1 - 0.1 12.9 0.3 0.19 12.0 0.0 1.6 2 0 0 2 2 2 0 Putative Interleukin 2 receptor, gamma chain HAUS6_N PF14661.6 KKK19096.1 - 2.1e-42 145.3 0.3 3.7e-42 144.5 0.3 1.4 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 6 N-terminus Rad4 PF03835.15 KKK19097.1 - 1.7e-38 131.6 0.4 4.9e-38 130.1 0.4 1.8 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_3 PF10405.9 KKK19097.1 - 2.7e-28 98.2 0.1 5e-28 97.3 0.1 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.9 KKK19097.1 - 1.1e-14 53.9 0.0 2.5e-14 52.8 0.0 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.9 KKK19097.1 - 3.7e-13 50.2 1.5 3.7e-13 50.2 1.5 4.1 4 0 0 4 4 4 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.19 KKK19097.1 - 0.0057 17.1 0.0 0.33 11.4 0.0 2.7 2 0 0 2 2 2 1 Transglutaminase-like superfamily CoA_binding_2 PF13380.6 KKK19098.1 - 2.1e-27 95.9 0.0 2.6e-27 95.6 0.0 1.1 1 0 0 1 1 1 1 CoA binding domain POTRA_TamA_1 PF17243.2 KKK19099.1 - 0.094 12.8 1.4 0.21 11.7 1.4 1.6 1 0 0 1 1 1 0 POTRA domain TamA domain 1 Mob1_phocein PF03637.17 KKK19100.1 - 2e-26 93.0 0.3 3.5e-26 92.2 0.0 1.5 2 0 0 2 2 2 1 Mob1/phocein family HIT PF01230.23 KKK19101.1 - 3.2e-23 82.3 0.1 4.5e-23 81.8 0.1 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 KKK19101.1 - 0.00016 22.1 0.0 0.00024 21.6 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding GalP_UDP_tr_C PF02744.17 KKK19101.1 - 0.064 13.0 0.0 0.089 12.5 0.0 1.3 1 0 0 1 1 1 0 Galactose-1-phosphate uridyl transferase, C-terminal domain cobW PF02492.19 KKK19102.1 - 8.4e-19 67.8 0.2 1.1e-18 67.5 0.2 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.6 KKK19102.1 - 0.00063 20.2 0.0 0.00067 20.1 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.27 KKK19102.1 - 0.0049 17.4 0.0 0.0055 17.2 0.0 1.2 1 0 0 1 1 1 1 ABC transporter ATPase_2 PF01637.18 KKK19102.1 - 0.0074 16.2 0.0 0.0084 16.0 0.0 1.1 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_23 PF13476.6 KKK19102.1 - 0.0078 16.7 0.0 0.0084 16.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 KKK19102.1 - 0.0083 15.2 0.0 0.0088 15.1 0.0 1.1 1 0 0 1 1 1 1 Type II/IV secretion system protein Zeta_toxin PF06414.12 KKK19102.1 - 0.0089 15.3 0.0 0.011 15.0 0.0 1.1 1 0 0 1 1 1 1 Zeta toxin AAA_29 PF13555.6 KKK19102.1 - 0.014 15.1 0.0 0.021 14.5 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain Rad17 PF03215.15 KKK19102.1 - 0.018 14.9 0.0 0.023 14.6 0.0 1.1 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_22 PF13401.6 KKK19102.1 - 0.021 15.1 0.0 0.028 14.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 KKK19102.1 - 0.021 14.8 0.1 0.035 14.1 0.1 1.4 1 1 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE MMR_HSR1 PF01926.23 KKK19102.1 - 0.028 14.5 0.0 0.037 14.1 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase SoxE PF06525.11 KKK19102.1 - 0.039 13.4 0.0 0.047 13.2 0.0 1.1 1 0 0 1 1 1 0 Sulfocyanin (SoxE) domain AAA_14 PF13173.6 KKK19102.1 - 0.041 13.9 0.0 0.053 13.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KKK19102.1 - 0.045 14.3 0.1 0.061 13.9 0.1 1.2 1 0 0 1 1 1 0 AAA domain Glyco_hydro_30C PF17189.4 KKK19102.1 - 0.046 13.9 0.0 0.072 13.3 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 30 beta sandwich domain RsgA_GTPase PF03193.16 KKK19102.1 - 0.047 13.6 0.0 0.052 13.4 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase MobB PF03205.14 KKK19102.1 - 0.048 13.6 0.1 0.057 13.3 0.1 1.2 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_30 PF13604.6 KKK19102.1 - 0.077 12.7 0.0 0.096 12.4 0.0 1.1 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 KKK19102.1 - 0.084 12.5 0.0 0.1 12.2 0.0 1.1 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Viral_helicase1 PF01443.18 KKK19102.1 - 0.099 12.4 0.0 0.12 12.1 0.0 1.1 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_33 PF13671.6 KKK19102.1 - 0.15 12.2 0.0 0.18 12.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain DUF2791 PF10923.8 KKK19102.1 - 0.2 10.5 0.0 0.25 10.1 0.0 1.1 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) Inp1 PF12634.7 KKK19131.1 - 2.5e-39 134.4 0.0 5.6e-39 133.3 0.0 1.6 1 0 0 1 1 1 1 Inheritance of peroxisomes protein 1 EI24 PF07264.11 KKK19132.1 - 1.6e-11 44.7 1.9 5.7e-10 39.7 1.9 2.2 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) DUF3742 PF12553.8 KKK19132.1 - 0.1 12.7 0.6 0.24 11.5 0.0 1.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3742) FmdA_AmdA PF03069.15 KKK19133.1 - 1.3e-180 600.1 0.0 1.5e-180 599.9 0.0 1.0 1 0 0 1 1 1 1 Acetamidase/Formamidase family FAD_binding_3 PF01494.19 KKK19134.1 - 1.1e-08 34.7 1.0 8e-08 31.9 1.0 1.9 1 1 0 1 1 1 1 FAD binding domain SRP14 PF02290.15 KKK19135.1 - 2.4e-27 95.1 0.2 3.9e-27 94.5 0.2 1.3 1 0 0 1 1 1 1 Signal recognition particle 14kD protein WAC_Acf1_DNA_bd PF10537.9 KKK19140.1 - 2e-39 134.2 1.3 2e-39 134.2 1.3 2.8 3 0 0 3 3 3 1 ATP-utilising chromatin assembly and remodelling N-terminal WSD PF15613.6 KKK19140.1 - 5.7e-22 78.0 0.7 5.7e-22 78.0 0.7 3.6 3 0 0 3 3 3 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif DDT PF02791.17 KKK19140.1 - 5.8e-17 61.7 1.5 1.2e-16 60.8 1.5 1.5 1 0 0 1 1 1 1 DDT domain WHIM1 PF15612.6 KKK19140.1 - 1.3e-09 37.4 0.1 3.3e-09 36.0 0.1 1.8 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 PLDc_2 PF13091.6 KKK19141.1 - 3.4e-14 52.9 0.2 1.1e-06 28.6 0.0 3.7 3 1 0 3 3 3 2 PLD-like domain PLDc PF00614.22 KKK19141.1 - 1.6e-12 47.1 2.5 2.3e-05 24.4 0.3 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif Regulator_TrmB PF11495.8 KKK19141.1 - 0.27 10.4 0.2 1.2 8.2 0.0 2.0 2 0 0 2 2 2 0 Archaeal transcriptional regulator TrmB DEAD PF00270.29 KKK19142.1 - 1.7e-16 60.5 0.0 4e-16 59.3 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KKK19142.1 - 2e-10 40.9 0.0 6.8e-10 39.2 0.0 2.0 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KKK19142.1 - 2.7e-06 27.7 0.0 7.3e-06 26.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PhoH PF02562.16 KKK19142.1 - 0.2 11.1 0.0 0.5 9.8 0.0 1.6 2 0 0 2 2 2 0 PhoH-like protein DHHC PF01529.20 KKK19143.1 - 6.5e-38 129.9 3.6 6.5e-38 129.9 3.6 3.4 5 0 0 5 5 5 1 DHHC palmitoyltransferase Rhomboid PF01694.22 KKK19143.1 - 5.9e-31 107.5 9.7 5.9e-31 107.5 9.7 2.7 3 0 0 3 3 3 1 Rhomboid family Vma12 PF11712.8 KKK19143.1 - 3.1 7.8 6.7 29 4.7 0.2 3.5 3 0 0 3 3 3 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Kinetochor_Ybp2 PF08568.10 KKK19144.1 - 1.9e-145 485.9 0.1 2.6e-144 482.1 0.1 1.9 1 1 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin UQ_con PF00179.26 KKK19146.1 - 7.5e-20 71.0 0.0 1.1e-19 70.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KKK19146.1 - 0.2 12.0 0.0 0.4 11.0 0.0 1.4 1 0 0 1 1 1 0 RWD domain VCBS PF13517.6 KKK19146.1 - 0.34 11.5 2.6 2.5 8.8 2.6 2.2 1 1 0 1 1 1 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella p450 PF00067.22 KKK19147.1 - 1.5e-63 215.1 0.0 3.1e-63 214.1 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 Snf7 PF03357.21 KKK19148.1 - 3.3e-18 65.9 21.3 5.2e-18 65.2 21.3 1.4 1 0 0 1 1 1 1 Snf7 PspA_IM30 PF04012.12 KKK19148.1 - 0.22 11.1 29.1 0.38 10.3 25.4 2.7 1 1 0 1 1 1 0 PspA/IM30 family DUF3300 PF11737.8 KKK19148.1 - 0.67 9.5 3.7 0.6 9.6 1.7 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3300) PIN_6 PF17146.4 KKK19148.1 - 1.1 9.8 5.6 7 7.2 0.0 3.4 2 1 1 3 3 3 0 PIN domain of ribonuclease PAXX PF15384.6 KKK19148.1 - 1.4 8.5 6.2 0.13 11.9 0.8 2.1 3 1 0 3 3 3 0 PAXX, PAralog of XRCC4 and XLF, also called C9orf142 DUF2203 PF09969.9 KKK19148.1 - 6 7.6 17.3 1.3 9.8 5.0 2.7 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) DASH_Dad2 PF08654.10 KKK19148.1 - 6.7 7.2 14.3 0.46 10.9 3.2 3.2 1 1 1 2 2 2 0 DASH complex subunit Dad2 TRAPPC-Trs85 PF12739.7 KKK19149.1 - 4.6e-109 365.1 0.0 6.9e-109 364.5 0.0 1.2 1 0 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit CDC27 PF09507.10 KKK19150.1 - 9.3e-112 374.5 18.1 1.1e-111 374.3 18.1 1.0 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 Ndc1_Nup PF09531.10 KKK19150.1 - 5.2 5.6 12.8 6.9 5.2 12.8 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Mitofilin PF09731.9 KKK19150.1 - 6.2 5.5 17.7 9.6 4.9 17.7 1.4 1 0 0 1 1 1 0 Mitochondrial inner membrane protein zf-C3HC4_2 PF13923.6 KKK19151.1 - 6.6e-12 45.1 15.8 6.8e-11 41.8 12.7 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KKK19151.1 - 1.7e-07 31.0 16.5 2.3e-07 30.6 10.0 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KKK19151.1 - 1.9e-07 30.8 13.0 1.9e-07 30.8 13.0 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) SAP PF02037.27 KKK19151.1 - 4e-07 29.6 0.0 9.4e-07 28.5 0.0 1.7 1 0 0 1 1 1 1 SAP domain zf-RING_UBOX PF13445.6 KKK19151.1 - 5.2e-07 29.6 16.4 5.3e-07 29.6 11.3 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 KKK19151.1 - 1.4e-06 28.1 16.8 2.1e-06 27.6 13.1 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_6 PF14835.6 KKK19151.1 - 1.9e-06 27.7 8.0 2.5e-06 27.3 6.1 2.2 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-RING_2 PF13639.6 KKK19151.1 - 3.4e-05 24.1 18.5 4.3e-05 23.8 13.2 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_4 PF15227.6 KKK19151.1 - 4.3e-05 23.6 12.9 4.3e-05 23.6 12.9 2.3 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 KKK19151.1 - 0.00011 22.0 14.4 0.081 12.8 11.7 2.4 2 0 0 2 2 2 2 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 KKK19151.1 - 0.00031 21.0 7.2 0.00031 21.0 7.2 2.2 2 0 0 2 2 2 1 RING-H2 zinc finger domain Mob_synth_C PF06463.13 KKK19151.1 - 0.00032 20.6 2.0 0.00068 19.6 2.0 1.5 1 0 0 1 1 1 1 Molybdenum Cofactor Synthesis C zf-RING_10 PF16685.5 KKK19151.1 - 0.0039 17.3 6.6 0.0039 17.3 6.6 1.8 2 0 0 2 2 2 1 zinc RING finger of MSL2 U-box PF04564.15 KKK19151.1 - 0.069 13.3 0.0 0.17 12.1 0.0 1.6 1 0 0 1 1 1 0 U-box domain Rad50_zn_hook PF04423.14 KKK19151.1 - 0.13 12.1 3.8 2.1 8.3 0.1 2.6 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-RING_4 PF14570.6 KKK19151.1 - 0.26 11.1 13.4 0.37 10.6 9.8 2.6 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-ANAPC11 PF12861.7 KKK19151.1 - 0.66 10.1 7.0 0.13 12.3 3.1 1.9 2 0 0 2 2 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Di19 PF05605.12 KKK19151.1 - 0.72 10.2 0.1 0.72 10.2 0.1 2.9 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.7 KKK19151.1 - 1.2 9.7 0.1 1.2 9.7 0.1 2.8 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-WRNIP1_ubi PF18279.1 KKK19151.1 - 1.2 9.9 4.8 0.82 10.4 0.1 3.0 3 0 0 3 3 3 0 Werner helicase-interacting protein 1 ubiquitin-binding domain YdjO PF14169.6 KKK19151.1 - 2.2 8.1 7.7 12 5.7 0.0 3.3 3 0 0 3 3 3 0 Cold-inducible protein YdjO HypA PF01155.19 KKK19151.1 - 4.5 7.3 7.5 10 6.2 5.0 2.6 2 1 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Pex2_Pex12 PF04757.14 KKK19152.1 - 3.2e-55 187.2 2.3 4.2e-55 186.8 2.3 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_4 PF15227.6 KKK19152.1 - 2.2e-05 24.5 3.4 4e-05 23.7 3.4 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 KKK19152.1 - 0.003 17.8 2.2 0.0058 16.9 2.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KKK19152.1 - 0.0044 17.0 3.5 0.0044 17.0 3.5 1.8 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KKK19152.1 - 0.0075 16.1 3.4 0.0098 15.7 2.1 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KKK19152.1 - 0.013 15.3 1.9 0.022 14.6 1.9 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KKK19152.1 - 0.024 14.5 2.4 0.042 13.7 2.4 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Auto_anti-p27 PF06677.12 KKK19152.1 - 2.9 8.1 4.1 5.1 7.3 4.1 1.4 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Glyco_hydro_125 PF06824.11 KKK19153.1 - 1.8e-182 606.9 0.0 2.1e-182 606.7 0.0 1.0 1 0 0 1 1 1 1 Metal-independent alpha-mannosidase (GH125) Mito_carr PF00153.27 KKK19154.1 - 3e-63 209.8 2.8 1.2e-21 76.5 0.0 4.2 4 0 0 4 4 4 4 Mitochondrial carrier protein Serine_protease PF18405.1 KKK19154.1 - 0.032 13.4 0.0 2.1 7.5 0.0 2.6 2 0 0 2 2 2 0 Gammaproteobacterial serine protease RsfS PF02410.15 KKK19155.1 - 6.8e-12 45.7 0.0 1.4e-11 44.6 0.0 1.6 1 0 0 1 1 1 1 Ribosomal silencing factor during starvation PolyA_pol PF01743.20 KKK19156.1 - 4.9e-24 85.2 0.2 1.1e-23 84.0 0.2 1.7 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 KKK19156.1 - 5.3e-07 29.3 0.0 1.2e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A tRNA_NucTran2_2 PF13735.6 KKK19156.1 - 0.0025 17.8 0.1 0.0062 16.5 0.1 1.6 1 0 0 1 1 1 1 tRNA nucleotidyltransferase domain 2 putative TetR_C_31 PF17940.1 KKK19156.1 - 0.0081 16.3 0.2 0.023 14.9 0.2 1.8 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain Tti2 PF10521.9 KKK19157.1 - 8.1e-95 317.6 0.6 1.2e-94 317.0 0.6 1.3 1 0 0 1 1 1 1 Tti2 family Abhydrolase_4 PF08386.10 KKK19159.1 - 2.2e-18 66.3 0.0 6.4e-18 64.8 0.0 1.8 2 0 0 2 2 2 1 TAP-like protein Abhydrolase_1 PF00561.20 KKK19159.1 - 2.2e-16 60.3 0.0 7.3e-15 55.3 0.0 2.5 2 1 0 2 2 2 1 alpha/beta hydrolase fold NAD_binding_4 PF07993.12 KKK19159.1 - 0.15 11.2 0.0 0.32 10.1 0.0 1.5 1 0 0 1 1 1 0 Male sterility protein DAO PF01266.24 KKK19160.1 - 5.1e-42 144.7 0.0 5.9e-42 144.5 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase TrkA_N PF02254.18 KKK19160.1 - 0.0007 19.8 0.1 0.02 15.1 0.0 2.4 2 0 0 2 2 2 1 TrkA-N domain Pyr_redox_2 PF07992.14 KKK19160.1 - 0.00079 18.8 0.1 0.037 13.2 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KKK19160.1 - 0.0058 15.8 0.2 0.15 11.1 0.0 2.3 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox PF00070.27 KKK19160.1 - 0.0066 17.0 0.1 0.023 15.2 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KKK19160.1 - 0.0066 16.7 0.2 0.013 15.7 0.2 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.21 KKK19160.1 - 0.021 14.1 0.1 0.74 9.1 0.1 2.3 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 KKK19160.1 - 0.068 12.4 0.0 0.69 9.1 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KKK19160.1 - 0.081 12.2 0.1 0.15 11.3 0.1 1.4 1 0 0 1 1 1 0 Thi4 family Sacchrp_dh_NADP PF03435.18 KKK19160.1 - 0.11 12.7 0.1 0.45 10.8 0.1 1.9 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain FAD_binding_2 PF00890.24 KKK19160.1 - 0.14 11.2 0.3 0.88 8.6 0.1 2.1 2 0 0 2 2 2 0 FAD binding domain DNA_pol_B PF00136.21 KKK19161.1 - 2.1e-147 491.6 2.7 2.9e-147 491.1 2.7 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 KKK19161.1 - 7.5e-83 278.4 0.1 1.6e-82 277.3 0.1 1.6 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 KKK19161.1 - 1.7e-18 66.8 5.6 3.6e-18 65.8 5.6 1.6 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta RNase_H_2 PF13482.6 KKK19161.1 - 0.0014 18.6 0.3 0.01 15.9 0.3 2.3 1 1 0 1 1 1 1 RNase_H superfamily DNA_pol_B_exo2 PF10108.9 KKK19161.1 - 0.096 12.3 0.1 0.2 11.3 0.1 1.5 1 0 0 1 1 1 0 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB Fer2_BFD PF04324.15 KKK19161.1 - 6.2 7.3 7.1 18 5.8 0.2 3.3 1 1 2 3 3 3 0 BFD-like [2Fe-2S] binding domain Podoplanin PF05808.11 KKK19162.1 - 0.002 18.3 0.0 0.0027 17.8 0.0 1.2 1 0 0 1 1 1 1 Podoplanin DUF4690 PF15756.5 KKK19162.1 - 0.015 15.9 0.2 0.035 14.7 0.2 1.6 1 0 0 1 1 1 0 Small Novel Rich in Cartilage Fibrinogen_C PF00147.18 KKK19162.1 - 0.053 13.3 0.0 0.075 12.8 0.0 1.3 1 0 0 1 1 1 0 Fibrinogen beta and gamma chains, C-terminal globular domain CytochromB561_N PF09786.9 KKK19163.1 - 0.29 10.1 8.1 0.38 9.7 8.1 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal PAP1 PF08601.10 KKK19163.1 - 2.5 7.8 15.0 3.3 7.4 15.0 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 Syja_N PF02383.18 KKK19164.1 - 2.1e-79 267.1 0.0 3.8e-79 266.3 0.0 1.4 1 0 0 1 1 1 1 SacI homology domain Pkinase PF00069.25 KKK19165.1 - 1.9e-31 109.4 0.0 3.8e-16 59.2 0.0 2.6 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KKK19165.1 - 6.3e-18 65.0 0.0 2.2e-06 27.2 0.0 3.3 3 0 0 3 3 3 3 Protein tyrosine kinase Kinase-like PF14531.6 KKK19165.1 - 0.027 13.8 0.1 0.37 10.0 0.0 2.5 3 0 0 3 3 3 0 Kinase-like FTA2 PF13095.6 KKK19165.1 - 0.042 13.5 0.0 5.1 6.7 0.0 2.4 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 OFCC1 PF15680.5 KKK19165.1 - 0.071 13.7 1.2 0.11 13.0 0.3 1.8 2 0 0 2 2 2 0 Orofacial cleft 1 candidate gene 1 protein FXa_inhibition PF14670.6 KKK19165.1 - 0.076 13.3 0.4 0.16 12.3 0.4 1.5 1 0 0 1 1 1 0 Coagulation Factor Xa inhibitory site Kdo PF06293.14 KKK19165.1 - 0.14 11.5 0.8 0.23 10.8 0.1 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Cyanate_lyase PF02560.14 KKK19167.1 - 2.9e-24 84.7 0.0 7.2e-24 83.4 0.0 1.7 1 0 0 1 1 1 1 Cyanate lyase C-terminal domain zf-C2H2_4 PF13894.6 KKK19167.1 - 1.3e-10 41.2 15.9 0.35 11.8 0.0 6.4 6 0 0 6 6 6 4 C2H2-type zinc finger zf-C2H2 PF00096.26 KKK19167.1 - 1.4e-10 41.0 12.2 0.066 13.7 0.0 6.2 6 0 0 6 6 6 3 Zinc finger, C2H2 type zf-Di19 PF05605.12 KKK19167.1 - 7.2e-06 26.2 9.9 0.021 15.1 2.5 3.7 2 1 0 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding Rad50_zn_hook PF04423.14 KKK19167.1 - 3.2e-05 23.7 10.4 0.00013 21.8 0.1 4.5 2 1 2 4 4 4 1 Rad50 zinc hook motif zf-H2C2_2 PF13465.6 KKK19167.1 - 0.00023 21.5 12.3 0.38 11.3 0.3 4.6 4 0 0 4 4 4 2 Zinc-finger double domain zf-RING_4 PF14570.6 KKK19167.1 - 0.0011 18.7 10.3 7.1 6.5 0.1 4.5 4 0 0 4 4 4 0 RING/Ubox like zinc-binding domain zf-C2H2_9 PF16293.5 KKK19167.1 - 0.0056 16.5 9.6 3.7 7.5 0.0 5.7 4 2 3 7 7 5 1 C2H2 type zinc-finger (1 copy) zf-C2H2_jaz PF12171.8 KKK19167.1 - 0.0076 16.5 10.1 1.4 9.3 1.0 5.7 5 1 1 6 6 6 1 Zinc-finger double-stranded RNA-binding HTH_31 PF13560.6 KKK19167.1 - 0.011 16.0 0.0 0.035 14.5 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain DUF2225 PF09986.9 KKK19167.1 - 0.013 15.2 8.6 0.11 12.2 0.0 4.0 3 1 1 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2225) CpXC PF14353.6 KKK19167.1 - 0.016 15.3 9.8 1.2 9.2 1.5 3.8 2 1 1 3 3 3 0 CpXC protein IBR PF01485.21 KKK19167.1 - 0.03 14.5 1.7 0.03 14.5 1.7 3.6 3 1 1 4 4 3 0 IBR domain, a half RING-finger domain zf-C2H2_8 PF15909.5 KKK19167.1 - 0.04 14.2 8.9 0.6 10.4 0.5 3.3 2 1 1 3 3 3 0 C2H2-type zinc ribbon zinc_ribbon_4 PF13717.6 KKK19167.1 - 0.046 13.7 11.1 7.9 6.5 0.2 3.8 3 1 0 3 3 3 0 zinc-ribbon domain zf-RING_14 PF17978.1 KKK19167.1 - 0.066 13.6 4.2 0.15 12.5 0.5 2.6 2 1 1 3 3 3 0 RING/Ubox like zinc-binding domain GAGA PF09237.11 KKK19167.1 - 0.071 12.9 3.5 0.081 12.7 0.1 2.6 3 0 0 3 3 3 0 GAGA factor FOXP-CC PF16159.5 KKK19167.1 - 0.096 13.3 8.1 4.3 8.0 0.0 4.1 2 1 2 4 4 4 0 FOXP coiled-coil domain Zn-ribbon_8 PF09723.10 KKK19167.1 - 0.097 12.8 18.2 0.13 12.4 2.2 4.3 2 1 3 5 5 5 0 Zinc ribbon domain PhnA_Zn_Ribbon PF08274.12 KKK19167.1 - 0.17 11.9 0.2 0.17 11.9 0.2 3.2 3 1 0 3 3 2 0 PhnA Zinc-Ribbon zf-RRN7 PF11781.8 KKK19167.1 - 0.19 11.5 1.6 4.7 7.0 0.2 2.8 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 zf-met PF12874.7 KKK19167.1 - 0.3 11.6 9.2 17 6.0 0.0 5.0 6 0 0 6 6 5 0 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 KKK19167.1 - 0.4 11.0 13.4 3.5 8.0 2.9 3.6 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-CSL PF05207.13 KKK19167.1 - 0.49 10.2 5.6 2.6 7.8 0.4 2.9 2 0 0 2 2 2 0 CSL zinc finger HNH_5 PF14279.6 KKK19167.1 - 0.72 9.8 7.6 5.6 6.9 2.1 3.3 3 0 0 3 3 3 0 HNH endonuclease zf-C2H2_6 PF13912.6 KKK19167.1 - 0.84 9.7 14.1 7.3 6.7 0.2 5.1 5 0 0 5 5 5 0 C2H2-type zinc finger DZR PF12773.7 KKK19167.1 - 1 9.4 15.5 0.84 9.7 6.0 3.3 2 1 0 2 2 2 0 Double zinc ribbon zinc_ribbon_9 PF14369.6 KKK19167.1 - 1.7 9.0 8.8 36 4.7 0.3 4.2 4 0 0 4 4 4 0 zinc-ribbon zinc_ribbon_5 PF13719.6 KKK19167.1 - 1.9 8.3 10.2 24 4.8 0.1 3.9 3 1 0 3 3 3 0 zinc-ribbon domain zf-C2HC_2 PF13913.6 KKK19167.1 - 3.1 7.8 10.2 6.1 6.9 0.2 4.2 4 0 0 4 4 4 0 zinc-finger of a C2HC-type Prok-RING_1 PF14446.6 KKK19167.1 - 7.5 6.6 10.4 19 5.3 3.1 3.8 3 1 0 3 3 3 0 Prokaryotic RING finger family 1 MBF1 PF08523.10 KKK19178.1 - 1.7e-24 86.1 0.6 1.7e-24 86.1 0.6 1.9 2 1 0 2 2 2 1 Multiprotein bridging factor 1 HTH_3 PF01381.22 KKK19178.1 - 3e-11 43.2 0.0 4.4e-11 42.7 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 KKK19178.1 - 0.00014 22.2 0.0 0.0003 21.1 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain WD40 PF00400.32 KKK19179.1 - 4.3e-27 93.8 1.9 7.2e-09 36.1 0.1 6.5 6 1 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKK19179.1 - 3.9e-10 39.9 0.1 0.019 15.2 0.1 5.7 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 KKK19179.1 - 9.1e-05 22.1 0.3 0.001 18.7 0.2 2.3 1 1 1 2 2 2 1 PQQ-like domain Nup160 PF11715.8 KKK19179.1 - 9.9e-05 21.2 0.1 0.00019 20.2 0.1 1.4 1 1 1 2 2 2 1 Nucleoporin Nup120/160 WD40_like PF17005.5 KKK19179.1 - 0.023 14.0 0.0 0.24 10.7 0.0 2.3 1 1 1 2 2 2 0 WD40-like domain Ank_2 PF12796.7 KKK19180.1 - 8.3e-29 100.0 7.7 1.1e-11 45.1 0.2 3.9 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KKK19180.1 - 4e-25 87.8 1.9 1.8e-11 44.3 0.0 5.2 2 1 4 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KKK19180.1 - 6.1e-20 69.2 3.4 0.0099 16.3 0.0 7.6 8 0 0 8 8 8 4 Ankyrin repeat Ank PF00023.30 KKK19180.1 - 2.8e-18 65.5 7.9 0.00077 19.8 0.0 6.8 5 1 1 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 KKK19180.1 - 7.8e-13 48.4 6.9 1.1e-07 32.0 0.1 4.8 2 1 3 5 5 5 4 Ankyrin repeats (many copies) SH3_1 PF00018.28 KKK19181.1 - 2.7e-14 52.5 0.0 4e-14 51.9 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KKK19181.1 - 1.9e-11 43.6 0.1 4.2e-11 42.5 0.0 1.6 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 KKK19181.1 - 1.1e-06 28.2 0.0 1.8e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain DUF2076 PF09849.9 KKK19181.1 - 1.9 8.5 7.6 0.33 11.0 3.7 1.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) Iso_dh PF00180.20 KKK19182.1 - 4e-72 243.3 0.0 4.8e-72 243.0 0.0 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Polysacc_lyase PF14099.6 KKK19183.1 - 0.17 11.7 0.0 0.28 11.0 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide lyase FTHFS PF01268.19 KKK19184.1 - 8.8e-251 832.9 0.0 1.2e-250 832.5 0.0 1.2 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.19 KKK19184.1 - 1.1e-66 223.1 1.1 2.7e-66 221.8 1.1 1.7 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 KKK19184.1 - 2.3e-38 131.0 0.7 5.3e-38 129.9 0.7 1.7 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain OCD_Mu_crystall PF02423.15 KKK19184.1 - 0.0074 15.3 0.1 0.014 14.3 0.1 1.4 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family eIF-5_eIF-2B PF01873.17 KKK19185.1 - 3.3e-41 139.8 0.1 5.3e-41 139.2 0.1 1.3 1 0 0 1 1 1 1 Domain found in IF2B/IF5 TF_Zn_Ribbon PF08271.12 KKK19185.1 - 0.19 11.3 1.3 0.39 10.3 1.3 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding Arc_trans_TRASH PF08394.10 KKK19185.1 - 1.4 9.3 7.5 1.2 9.5 0.4 2.7 1 1 1 2 2 2 0 Archaeal TRASH domain zf-HYPF PF07503.12 KKK19185.1 - 5.4 6.9 6.8 27 4.6 3.9 2.7 2 1 1 3 3 3 0 HypF finger AIM24 PF01987.17 KKK19186.1 - 2.7e-51 174.3 0.1 3.1e-51 174.0 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 ChaC PF04752.12 KKK19189.1 - 1.9e-54 184.5 0.0 2.3e-54 184.1 0.0 1.1 1 0 0 1 1 1 1 ChaC-like protein DUF4695 PF15766.5 KKK19189.1 - 0.11 12.7 2.0 0.2 11.9 2.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4695) RRM_1 PF00076.22 KKK19190.1 - 3e-21 75.0 0.0 4.1e-21 74.6 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KKK19190.1 - 0.025 14.4 0.0 0.048 13.5 0.0 1.5 1 1 0 1 1 1 0 Occluded RNA-recognition motif RRM_8 PF11835.8 KKK19190.1 - 0.058 13.6 0.0 0.08 13.2 0.0 1.2 1 0 0 1 1 1 0 RRM-like domain RRM_5 PF13893.6 KKK19190.1 - 0.11 12.0 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KKK19190.1 - 0.15 12.2 0.1 0.22 11.6 0.1 1.2 1 0 0 1 1 1 0 RNA binding motif EF-hand_1 PF00036.32 KKK19191.1 - 4e-21 72.9 5.7 7.3e-07 28.3 0.0 4.7 4 1 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 KKK19191.1 - 1.6e-20 71.2 1.2 7.1e-06 25.6 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.6 KKK19191.1 - 4.6e-20 71.8 0.4 1.1e-08 35.4 0.0 3.3 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_8 PF13833.6 KKK19191.1 - 6.2e-16 58.0 2.9 8.9e-08 31.9 0.0 3.8 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 KKK19191.1 - 3e-15 54.9 6.4 1.1e-05 24.7 0.3 4.1 4 1 0 4 4 4 3 EF hand adh_short PF00106.25 KKK19192.1 - 2.6e-18 66.2 0.0 6.6e-16 58.3 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KKK19192.1 - 6.3e-13 48.8 0.0 9e-09 35.2 0.0 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KKK19192.1 - 3.7e-06 27.0 0.0 5.5e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 KR domain MFS_1 PF07690.16 KKK19193.1 - 5.5e-49 167.0 59.5 9.5e-49 166.2 56.9 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KKK19193.1 - 1.4e-16 60.1 19.9 5.3e-16 58.2 19.9 1.8 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KKK19193.1 - 1.2e-14 54.1 7.3 1.2e-14 54.1 7.3 3.2 2 1 0 3 3 3 2 Sugar (and other) transporter SKG6 PF08693.10 KKK19196.1 - 2.8e-05 23.4 3.7 2.8e-05 23.4 3.7 1.8 2 0 0 2 2 2 1 Transmembrane alpha-helix domain DUF4448 PF14610.6 KKK19196.1 - 0.00014 21.7 0.0 0.00021 21.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) TMEM154 PF15102.6 KKK19196.1 - 0.00081 19.3 1.8 0.0013 18.7 1.0 1.7 1 1 0 1 1 1 1 TMEM154 protein family DUF3188 PF11384.8 KKK19196.1 - 0.0024 17.5 0.7 0.0042 16.7 0.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3188) EphA2_TM PF14575.6 KKK19196.1 - 0.013 16.3 0.0 0.047 14.6 0.0 1.9 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF2370 PF10176.9 KKK19196.1 - 0.029 14.0 2.2 0.056 13.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2370) Adeno_E3_CR2 PF02439.15 KKK19196.1 - 0.04 13.7 0.1 0.07 12.9 0.1 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 AJAP1_PANP_C PF15298.6 KKK19196.1 - 0.069 13.4 6.2 0.11 12.6 6.2 1.3 1 0 0 1 1 1 0 AJAP1/PANP C-terminus RIFIN PF02009.16 KKK19196.1 - 0.25 11.2 0.0 0.33 10.8 0.0 1.1 1 0 0 1 1 1 0 Rifin Orf78 PF06024.12 KKK19196.1 - 1.7 9.0 5.6 35 4.8 5.6 2.3 1 1 0 1 1 1 0 Orf78 (ac78) AIM3 PF17096.5 KKK19197.1 - 0.00082 20.3 0.1 0.00082 20.3 0.1 5.3 5 1 0 5 5 5 2 Altered inheritance of mitochondria protein 3 ELO PF01151.18 KKK19199.1 - 2.2e-85 286.2 5.8 2.7e-85 285.9 5.8 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family BLOC1S3 PF15753.5 KKK19199.1 - 0.17 12.0 3.1 0.28 11.3 3.1 1.3 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 Glyco_hydro_35 PF01301.19 KKK19200.1 - 2.5e-79 267.2 2.6 2.5e-79 267.2 2.6 1.9 2 1 0 2 2 2 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.6 KKK19200.1 - 3.7e-63 211.2 8.3 8.5e-35 119.8 0.1 3.3 3 0 0 3 3 3 2 Beta-galactosidase jelly roll domain BetaGal_dom2 PF10435.9 KKK19200.1 - 1.7e-62 210.4 0.3 3.5e-62 209.4 0.3 1.5 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom3 PF13363.6 KKK19200.1 - 1.3e-27 95.1 0.1 2.9e-27 94.0 0.1 1.6 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 MFS_1 PF07690.16 KKK19201.1 - 5.3e-36 124.3 22.9 7.8e-36 123.7 22.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily TAF4 PF05236.14 KKK19203.1 - 1.7e-31 110.0 0.7 3.2e-23 82.9 1.5 2.1 2 0 0 2 2 2 2 Transcription initiation factor TFIID component TAF4 family Pkinase PF00069.25 KKK19204.1 - 2.6e-47 161.4 0.0 1.5e-46 158.9 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK19204.1 - 1.3e-19 70.6 0.0 1.4e-18 67.1 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase TruD PF01142.18 KKK19205.1 - 3e-60 204.2 0.1 2.6e-53 181.3 0.0 4.0 3 2 0 3 3 3 3 tRNA pseudouridine synthase D (TruD) CPSF73-100_C PF11718.8 KKK19206.1 - 4.5e-84 281.4 0.2 4.5e-84 281.4 0.2 1.5 2 0 0 2 2 2 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.8 KKK19206.1 - 1.2e-29 102.7 0.0 2.9e-29 101.6 0.0 1.7 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B PF00753.27 KKK19206.1 - 3.2e-21 76.3 0.1 6.2e-21 75.3 0.1 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_6 PF16661.5 KKK19206.1 - 7e-16 58.2 0.0 1.1e-15 57.5 0.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain RMMBL PF07521.12 KKK19206.1 - 1.4e-11 44.2 0.0 3.2e-11 43.0 0.0 1.6 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_2 PF12706.7 KKK19206.1 - 3.4e-05 23.4 0.2 9.1e-05 22.1 0.2 1.7 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KKK19206.1 - 0.0002 21.3 0.0 0.00081 19.3 0.0 2.0 1 1 0 1 1 1 1 Beta-lactamase superfamily domain IL15 PF02372.15 KKK19206.1 - 0.17 11.9 0.1 0.48 10.4 0.1 1.7 1 0 0 1 1 1 0 Interleukin 15 TMA7 PF09072.10 KKK19237.1 - 4e-26 91.6 17.7 4.4e-26 91.5 17.7 1.0 1 0 0 1 1 1 1 Translation machinery associated TMA7 DHR10 PF18595.1 KKK19238.1 - 0.25 11.4 3.1 0.41 10.7 3.1 1.2 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain Pkinase PF00069.25 KKK19239.1 - 1.9e-53 181.5 0.0 2.4e-53 181.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK19239.1 - 1.4e-32 113.0 0.0 1.7e-32 112.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KKK19239.1 - 0.0021 18.0 0.0 0.0071 16.3 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KKK19239.1 - 0.0051 16.2 0.0 0.011 15.1 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 KKK19239.1 - 0.0085 15.5 0.0 0.012 14.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KKK19239.1 - 0.067 12.1 0.0 0.097 11.6 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Choline_kinase PF01633.20 KKK19239.1 - 0.18 11.4 0.0 0.33 10.5 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pkinase PF00069.25 KKK19240.1 - 2.3e-54 184.5 0.0 3.3e-54 184.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK19240.1 - 2.5e-23 82.7 0.0 8.9e-23 80.9 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 KKK19240.1 - 0.049 12.6 0.1 0.074 12.0 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Cyt-b5 PF00173.28 KKK19241.1 - 0.028 14.6 0.0 0.035 14.2 0.0 1.2 1 0 0 1 1 1 0 Cytochrome b5-like Heme/Steroid binding domain HlyIII PF03006.20 KKK19242.1 - 1.4e-64 217.9 9.5 1.7e-64 217.6 9.5 1.1 1 0 0 1 1 1 1 Haemolysin-III related Peptidase_U4 PF03419.13 KKK19242.1 - 0.076 12.3 5.9 0.027 13.8 3.1 1.7 1 1 1 2 2 2 0 Sporulation factor SpoIIGA TFIIB PF00382.19 KKK19244.1 - 7e-39 131.7 0.2 5.1e-19 68.1 0.1 2.4 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 KKK19244.1 - 3e-10 39.4 0.8 3e-10 39.4 0.8 1.7 2 0 0 2 2 2 1 TFIIB zinc-binding RB_B PF01857.20 KKK19244.1 - 0.0013 18.7 0.1 0.0036 17.4 0.1 1.7 2 0 0 2 2 2 1 Retinoblastoma-associated protein B domain Cyclin_N PF00134.23 KKK19244.1 - 0.012 15.3 0.3 2.4 7.9 0.1 2.4 2 0 0 2 2 2 0 Cyclin, N-terminal domain Cyclin_C PF02984.19 KKK19244.1 - 0.033 14.3 0.0 7.4 6.7 0.0 2.5 2 1 0 2 2 2 0 Cyclin, C-terminal domain Sigma70_r4 PF04545.16 KKK19244.1 - 0.067 12.7 0.0 0.36 10.4 0.0 2.1 2 0 0 2 2 2 0 Sigma-70, region 4 TMIE PF16038.5 KKK19244.1 - 1 9.2 5.5 0.5 10.2 0.6 2.5 2 0 0 2 2 2 0 TMIE protein zf-ribbon_3 PF13248.6 KKK19244.1 - 1.2 8.7 6.2 8.6 5.9 0.3 2.6 3 0 0 3 3 3 0 zinc-ribbon domain ATP_sub_h PF10775.9 KKK19245.1 - 1.1e-27 95.8 0.4 1.5e-27 95.4 0.4 1.2 1 0 0 1 1 1 1 ATP synthase complex subunit h ATP-synt_F6 PF05511.11 KKK19245.1 - 0.015 15.7 0.0 0.021 15.2 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ATP synthase coupling factor 6 CSN8_PSD8_EIF3K PF10075.9 KKK19246.1 - 0.00036 20.5 0.1 0.00068 19.6 0.1 1.4 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family SAC3_GANP PF03399.16 KKK19246.1 - 0.042 13.2 0.0 0.061 12.7 0.0 1.2 1 0 0 1 1 1 0 SAC3/GANP family TPR_19 PF14559.6 KKK19247.1 - 1.2e-11 44.9 0.1 6.1e-05 23.5 0.1 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 KKK19247.1 - 0.00015 22.4 0.0 0.15 12.7 0.1 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 KKK19247.1 - 0.00018 21.4 0.1 0.35 11.1 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 KKK19247.1 - 0.00077 19.9 0.5 5.8 7.8 0.0 3.8 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 KKK19247.1 - 0.0016 18.5 0.0 10 6.6 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_21 PF09976.9 KKK19247.1 - 0.0017 18.1 0.7 0.081 12.6 0.1 2.2 1 1 1 2 2 2 1 Tetratricopeptide repeat-like domain BTAD PF03704.17 KKK19247.1 - 0.0083 16.6 2.4 2.1 8.8 0.2 2.4 2 0 0 2 2 2 2 Bacterial transcriptional activator domain TPR_12 PF13424.6 KKK19247.1 - 0.019 15.3 0.3 0.019 15.3 0.3 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 KKK19247.1 - 0.089 12.4 0.7 5 6.8 0.1 2.5 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB1_HrpK) TPR_4 PF07721.14 KKK19247.1 - 0.12 13.1 0.1 58 4.7 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Coatomer_E PF04733.14 KKK19247.1 - 0.13 11.6 0.5 0.73 9.2 0.1 1.9 2 0 0 2 2 2 0 Coatomer epsilon subunit Cg6151-P PF10233.9 KKK19248.1 - 2.6e-45 153.4 15.6 3.1e-45 153.1 15.6 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P TMEM72 PF16054.5 KKK19248.1 - 0.00013 21.7 7.8 0.00018 21.3 7.8 1.2 1 0 0 1 1 1 1 Transmembrane protein family 72 COPI_assoc PF08507.10 KKK19248.1 - 0.0015 18.6 11.9 0.0023 18.0 11.9 1.4 1 0 0 1 1 1 1 COPI associated protein DHHC PF01529.20 KKK19248.1 - 0.76 9.9 7.4 1.1 9.3 7.4 1.3 1 0 0 1 1 1 0 DHHC palmitoyltransferase S_4TM PF18159.1 KKK19248.1 - 2.2 7.5 8.9 4.1 6.6 3.0 2.1 2 0 0 2 2 2 0 SMODS-associating 4TM effector domain YtpI PF14007.6 KKK19248.1 - 3 8.0 16.2 3.5 7.8 5.7 2.8 1 1 2 3 3 3 0 YtpI-like protein Aim21 PF11489.8 KKK19249.1 - 7.9e-273 907.7 69.0 7.9e-273 907.7 69.0 1.4 2 0 0 2 2 2 1 Altered inheritance of mitochondria protein 21 SRF-TF PF00319.18 KKK19274.1 - 3.3e-21 74.5 0.1 5e-21 73.9 0.1 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Mg_trans_NIPA PF05653.14 KKK19275.1 - 3.4e-17 62.5 12.7 7e-09 35.2 2.3 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA PUNUT PF16913.5 KKK19275.1 - 1.1e-06 28.2 0.5 1.1e-06 28.2 0.5 2.0 2 0 0 2 2 2 1 Purine nucleobase transmembrane transport EamA PF00892.20 KKK19275.1 - 6.7e-05 23.1 5.8 6.7e-05 23.1 5.8 3.2 3 2 1 4 4 4 1 EamA-like transporter family UAA PF08449.11 KKK19275.1 - 0.00066 19.0 0.3 0.0012 18.1 0.3 1.4 1 0 0 1 1 1 1 UAA transporter family Multi_Drug_Res PF00893.19 KKK19275.1 - 1.1 10.0 13.4 2.9 8.6 2.1 3.1 2 2 0 2 2 2 0 Small Multidrug Resistance protein Neurensin PF14927.6 KKK19275.1 - 1.2 8.9 7.8 5.6 6.7 2.1 3.2 2 1 0 2 2 2 0 Neurensin vATP-synt_E PF01991.18 KKK19276.1 - 9.7e-63 211.2 12.2 1.1e-62 211.0 12.2 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit PhoLip_ATPase_C PF16212.5 KKK19278.1 - 2.5e-82 276.4 24.4 2.5e-82 276.4 24.4 2.6 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KKK19278.1 - 3.6e-19 68.2 0.6 1e-18 66.7 0.6 1.8 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 KKK19278.1 - 5.1e-14 53.1 0.0 4.5e-09 36.9 0.0 2.6 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KKK19278.1 - 3.7e-11 43.0 0.0 1.7e-10 40.9 0.0 2.0 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 KKK19278.1 - 0.0016 18.0 0.0 0.0016 18.0 0.0 2.7 3 1 0 3 3 3 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KKK19278.1 - 0.07 12.9 0.1 0.16 11.7 0.1 1.5 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase SEN1_N PF12726.7 KKK19279.1 - 1.1e-211 705.0 10.0 1.5e-211 704.6 10.0 1.1 1 0 0 1 1 1 1 SEN1 N terminal AAA_11 PF13086.6 KKK19279.1 - 4.3e-71 239.8 0.8 4.3e-71 239.8 0.8 2.8 3 0 0 3 3 3 1 AAA domain AAA_12 PF13087.6 KKK19279.1 - 1.7e-61 207.3 0.0 4.1e-61 206.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KKK19279.1 - 2.7e-09 37.0 0.1 2e-05 24.4 0.1 3.0 3 0 0 3 3 3 2 AAA domain AAA_19 PF13245.6 KKK19279.1 - 2.9e-07 30.9 0.0 8.2e-07 29.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain UvrD-helicase PF00580.21 KKK19279.1 - 1.2e-06 28.3 1.0 8.2e-06 25.5 0.1 2.6 2 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain Viral_helicase1 PF01443.18 KKK19279.1 - 4.7e-06 26.5 0.2 0.083 12.6 0.0 3.5 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase DEAD PF00270.29 KKK19279.1 - 0.00072 19.4 0.1 0.0023 17.7 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase zf-CCHC PF00098.23 KKK19279.1 - 0.0067 16.5 2.9 0.0067 16.5 2.9 3.1 3 0 0 3 3 2 2 Zinc knuckle AAA PF00004.29 KKK19279.1 - 0.078 13.4 0.1 0.41 11.1 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 KKK19279.1 - 0.083 11.9 0.0 0.16 11.0 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF1981 PF09324.10 KKK19279.1 - 0.092 12.6 0.0 0.32 10.9 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1981) ResIII PF04851.15 KKK19279.1 - 0.12 12.4 0.0 0.37 10.8 0.0 2.0 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit zf-CCHC_3 PF13917.6 KKK19279.1 - 0.19 11.7 19.5 1.4 8.9 1.7 4.1 1 1 1 2 2 2 0 Zinc knuckle HMA PF00403.26 KKK19309.1 - 0.00016 22.0 0.1 0.00017 22.0 0.1 1.1 1 0 0 1 1 1 1 Heavy-metal-associated domain L31 PF09784.9 KKK19332.1 - 2.4e-45 153.1 1.1 2.6e-45 153.0 1.1 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 PI3K_C2 PF00792.24 KKK19332.1 - 0.13 12.1 0.0 0.19 11.7 0.0 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase C2 DEAD PF00270.29 KKK19334.1 - 1.2e-39 135.9 0.1 2.3e-39 135.0 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KKK19334.1 - 9.7e-30 103.2 0.2 3.6e-29 101.3 0.1 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KKK19334.1 - 0.0011 19.0 0.0 0.0047 17.0 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit TERB2 PF15101.6 KKK19334.1 - 0.093 12.8 0.3 0.21 11.6 0.3 1.5 1 0 0 1 1 1 0 Telomere-associated protein TERB2 p450 PF00067.22 KKK19335.1 - 4e-68 230.3 0.0 4.6e-68 230.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Acyltransferase PF01553.21 KKK19336.1 - 1.2e-14 54.0 0.0 2.2e-14 53.2 0.0 1.4 1 1 0 1 1 1 1 Acyltransferase Pkinase PF00069.25 KKK19341.1 - 7.8e-67 225.4 0.0 9.1e-67 225.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK19341.1 - 1e-25 90.5 0.0 1.4e-25 90.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KKK19341.1 - 3.4e-06 26.6 0.0 1.7e-05 24.3 0.0 2.0 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KKK19341.1 - 0.0038 17.2 0.2 0.02 14.8 0.0 2.0 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 KKK19341.1 - 0.16 11.3 0.0 0.25 10.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family MIF4G_like PF09088.11 KKK19342.1 - 9.4e-92 306.0 0.1 1.4e-91 305.4 0.1 1.3 1 0 0 1 1 1 1 MIF4G like MIF4G_like_2 PF09090.11 KKK19342.1 - 2e-74 250.5 0.0 2.9e-74 249.9 0.0 1.3 1 0 0 1 1 1 1 MIF4G like MIF4G PF02854.19 KKK19342.1 - 0.00067 19.4 0.1 0.0023 17.6 0.0 1.9 3 0 0 3 3 3 1 MIF4G domain cobW PF02492.19 KKK19359.1 - 7.4e-33 113.6 0.0 9.1e-33 113.3 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 KKK19359.1 - 1.1e-05 24.6 1.2 0.00013 21.0 1.2 2.0 1 1 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB MMR_HSR1 PF01926.23 KKK19359.1 - 0.007 16.4 0.0 0.014 15.5 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_18 PF13238.6 KKK19359.1 - 0.016 15.7 0.0 0.025 15.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KKK19359.1 - 0.018 15.4 0.0 0.024 15.0 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.14 KKK19359.1 - 0.025 14.6 0.0 0.037 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) TIP49 PF06068.13 KKK19359.1 - 0.025 13.8 0.0 0.038 13.2 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain IstB_IS21 PF01695.17 KKK19359.1 - 0.044 13.5 0.0 0.085 12.6 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein PRK PF00485.18 KKK19359.1 - 0.055 13.2 0.1 0.19 11.5 0.0 1.8 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_21 PF13304.6 KKK19359.1 - 0.068 13.0 0.0 0.12 12.1 0.0 1.5 1 1 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KKK19359.1 - 0.11 13.0 0.0 0.13 12.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain CbiA PF01656.23 KKK19359.1 - 0.12 12.4 0.0 0.19 11.8 0.0 1.4 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Zeta_toxin PF06414.12 KKK19359.1 - 0.16 11.2 0.0 0.28 10.5 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin NACHT PF05729.12 KKK19359.1 - 0.16 11.9 0.0 0.26 11.2 0.0 1.3 1 0 0 1 1 1 0 NACHT domain ResIII PF04851.15 KKK19359.1 - 0.18 11.8 0.0 0.26 11.3 0.0 1.4 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit S8_pro-domain PF16470.5 KKK19361.1 - 0.0022 18.7 0.6 0.0044 17.7 0.6 1.5 1 0 0 1 1 1 1 Peptidase S8 pro-domain DLH PF01738.18 KKK19362.1 - 3.3e-10 39.9 0.0 3.8e-10 39.7 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family RSN1_7TM PF02714.15 KKK19363.1 - 5.8e-91 304.6 30.6 1.6e-89 299.9 20.0 2.8 3 0 0 3 3 3 2 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 KKK19363.1 - 2.4e-46 157.4 3.9 2.4e-46 157.4 3.9 2.8 4 0 0 4 4 4 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 KKK19363.1 - 6.2e-37 127.5 0.2 1e-36 126.8 0.2 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 KKK19363.1 - 3.6e-32 110.4 0.4 9.5e-32 109.0 0.2 1.8 2 0 0 2 2 2 1 Extracellular tail, of 10TM putative phosphate transporter DUF3493 PF11998.8 KKK19363.1 - 1 9.6 6.9 8.3 6.7 0.0 3.2 3 0 0 3 3 3 0 Low psii accumulation1 / Rep27 Orf78 PF06024.12 KKK19363.1 - 1.1 9.6 6.2 21 5.5 0.1 3.3 2 0 0 2 2 2 0 Orf78 (ac78) TMEM154 PF15102.6 KKK19363.1 - 3.5 7.5 8.7 0.43 10.5 0.3 3.0 2 0 0 2 2 2 0 TMEM154 protein family Insulin_TMD PF17870.1 KKK19363.1 - 7.3 6.8 12.9 9.9 6.3 0.1 3.5 3 0 0 3 3 3 0 Insulin receptor trans-membrane segment MCM PF00493.23 KKK19364.1 - 7.4e-99 329.4 0.1 1e-98 328.9 0.1 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KKK19364.1 - 1.1e-39 135.1 0.7 2.3e-39 134.1 0.7 1.5 1 0 0 1 1 1 1 MCM OB domain MCM6_C PF18263.1 KKK19364.1 - 5.7e-34 116.6 1.0 5.7e-34 116.6 1.0 2.3 2 0 0 2 2 2 1 MCM6 C-terminal winged-helix domain MCM_lid PF17855.1 KKK19364.1 - 2.3e-24 85.6 0.4 7.9e-24 83.9 0.4 2.0 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KKK19364.1 - 3.3e-21 75.8 0.7 9.8e-21 74.3 0.7 1.9 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 KKK19364.1 - 2.4e-05 23.8 0.0 0.00024 20.6 0.0 2.4 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI GIDA_assoc PF13932.6 KKK19364.1 - 0.002 18.3 0.5 0.0045 17.2 0.5 1.5 1 0 0 1 1 1 1 GidA associated domain AAA_5 PF07728.14 KKK19364.1 - 0.0029 17.6 0.0 0.0074 16.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 KKK19364.1 - 0.0037 17.1 0.0 0.015 15.1 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KKK19364.1 - 0.0039 16.9 0.0 0.0083 15.9 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain Npa1 PF11707.8 KKK19366.1 - 1.9e-100 336.5 0.3 1.9e-100 336.5 0.3 2.1 2 0 0 2 2 2 1 Ribosome 60S biogenesis N-terminal NopRA1 PF16201.5 KKK19366.1 - 2.4e-54 184.0 0.6 8.7e-54 182.2 0.0 2.4 4 0 0 4 4 4 1 Nucleolar pre-ribosomal-associated protein 1 Creb_binding PF09030.10 KKK19366.1 - 0.021 15.5 0.1 0.12 13.1 0.0 2.3 2 0 0 2 2 2 0 Creb binding DUF1365 PF07103.11 KKK19367.1 - 4e-30 105.2 0.0 5.7e-30 104.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1365) FMO-like PF00743.19 KKK19368.1 - 2.4e-12 46.1 0.1 1.6e-10 40.0 0.3 2.8 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KKK19368.1 - 7.2e-11 41.8 0.0 9.6e-08 31.6 0.0 2.4 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KKK19368.1 - 1.6e-10 41.0 0.0 4.2e-10 39.7 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KKK19368.1 - 8.5e-09 35.6 0.0 0.00011 22.2 0.0 2.8 3 0 0 3 3 3 2 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 KKK19368.1 - 4.3e-08 32.8 0.0 0.00017 21.0 0.0 3.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KKK19368.1 - 4.9e-07 29.2 0.0 0.0053 15.9 0.0 3.1 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 KKK19368.1 - 3.2e-06 27.0 0.0 0.00027 20.6 0.0 3.0 3 0 0 3 3 3 1 FAD dependent oxidoreductase Thi4 PF01946.17 KKK19368.1 - 0.0017 17.7 0.0 0.0037 16.5 0.0 1.5 1 0 0 1 1 1 1 Thi4 family Amino_oxidase PF01593.24 KKK19368.1 - 0.0019 17.6 0.0 0.1 11.9 0.0 2.1 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 KKK19368.1 - 0.0021 18.6 0.0 0.09 13.4 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 KKK19368.1 - 0.015 15.4 0.0 4.1 7.5 0.0 2.5 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase GIDA PF01134.22 KKK19368.1 - 0.035 13.2 0.0 3.9 6.5 0.0 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_binding_2 PF00890.24 KKK19368.1 - 0.14 11.2 0.0 0.24 10.4 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain Malate_synthase PF01274.22 KKK19369.1 - 7.8e-185 615.1 0.0 8.8e-185 614.9 0.0 1.0 1 0 0 1 1 1 1 Malate synthase HpcH_HpaI PF03328.14 KKK19369.1 - 0.14 11.3 0.0 0.33 10.0 0.0 1.6 1 1 0 1 1 1 0 HpcH/HpaI aldolase/citrate lyase family COX16 PF14138.6 KKK19384.1 - 1.9e-31 108.4 0.2 2.5e-31 108.0 0.2 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 Nic96 PF04097.14 KKK19385.1 - 1.2e-217 724.3 0.0 1.5e-217 724.0 0.0 1.0 1 0 0 1 1 1 1 Nup93/Nic96 Nucleoporin_FG PF13634.6 KKK19385.1 - 7.1e-05 23.6 20.2 7.1e-05 23.6 20.2 2.9 3 0 0 3 3 3 1 Nucleoporin FG repeat region F-box PF00646.33 KKK19386.1 - 0.02 14.8 0.0 0.052 13.4 0.0 1.6 1 0 0 1 1 1 0 F-box domain DUF1497 PF07384.11 KKK19386.1 - 0.2 12.1 0.8 0.4 11.1 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1497) Y_phosphatase PF00102.27 KKK19387.1 - 8.9e-61 205.4 0.0 8.9e-61 205.4 0.0 2.9 2 1 0 2 2 2 1 Protein-tyrosine phosphatase Rhodanese PF00581.20 KKK19387.1 - 1.7e-10 41.3 0.0 2.3e-09 37.7 0.0 2.6 2 0 0 2 2 2 1 Rhodanese-like domain DSPc PF00782.20 KKK19387.1 - 0.0012 18.7 0.0 0.0036 17.1 0.0 1.7 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain TFIIA PF03153.13 KKK19387.1 - 0.0067 16.5 2.9 0.0067 16.5 2.9 1.6 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit Y_phosphatase3 PF13350.6 KKK19387.1 - 0.011 15.7 0.9 0.02 14.9 0.0 1.9 2 0 0 2 2 2 0 Tyrosine phosphatase family DDE_Tnp_IS240 PF13610.6 KKK19387.1 - 0.04 14.1 0.0 0.076 13.2 0.0 1.4 1 0 0 1 1 1 0 DDE domain SUIM_assoc PF16619.5 KKK19387.1 - 0.058 13.5 10.3 0.16 12.0 10.3 1.8 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 KKK19387.1 - 0.074 12.7 9.1 0.15 11.7 9.1 1.4 1 0 0 1 1 1 0 Spt20 family Hydin_ADK PF17213.3 KKK19387.1 - 0.11 12.7 0.0 0.43 10.8 0.1 1.9 3 0 0 3 3 3 0 Hydin Adenylate kinase-like domain Activator_LAG-3 PF11498.8 KKK19387.1 - 0.19 10.7 14.8 0.31 10.0 14.8 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 RibD_C PF01872.17 KKK19389.1 - 3.5e-30 105.4 0.0 5.2e-30 104.8 0.0 1.3 1 0 0 1 1 1 1 RibD C-terminal domain Pex14_N PF04695.13 KKK19389.1 - 0.0064 17.2 11.4 0.013 16.1 11.4 1.5 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region CCDC53 PF10152.9 KKK19389.1 - 5.5 7.4 9.4 11 6.4 9.4 1.5 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Lin-8 PF03353.15 KKK19389.1 - 9.9 5.6 7.5 14 5.1 7.5 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist RCC1 PF00415.18 KKK19390.1 - 4.3e-60 200.1 12.6 3.8e-11 43.4 0.1 7.4 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KKK19390.1 - 1.2e-34 117.3 38.3 5.6e-09 35.6 1.2 6.7 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat AA_permease PF00324.21 KKK19392.1 - 1e-109 367.3 39.2 1.2e-109 367.1 39.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KKK19392.1 - 8e-28 97.4 41.7 1e-27 97.0 41.7 1.1 1 0 0 1 1 1 1 Amino acid permease Mannosidase_ig PF17786.1 KKK19393.1 - 2e-17 63.6 3.2 2.8e-17 63.1 0.6 2.5 3 0 0 3 3 3 1 Mannosidase Ig/CBM-like domain Glyco_hydro_2 PF00703.21 KKK19393.1 - 3.4e-12 47.0 0.1 1e-11 45.4 0.1 1.9 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.18 KKK19393.1 - 0.00015 21.7 0.1 0.0006 19.8 0.0 2.0 2 1 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.17 KKK19393.1 - 0.0024 17.0 0.3 0.012 14.7 0.3 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Mannosyl_trans PF05007.13 KKK19394.1 - 1.9e-72 244.2 9.3 2e-57 195.0 9.9 2.4 2 0 0 2 2 2 2 Mannosyltransferase (PIG-M) Fungal_trans PF04082.18 KKK19394.1 - 7.7e-18 64.5 0.4 7.7e-18 64.5 0.4 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain PIG-U PF06728.13 KKK19394.1 - 5.8e-10 38.8 5.5 2.3e-09 36.8 5.5 2.0 1 1 0 1 1 1 1 GPI transamidase subunit PIG-U Zn_clus PF00172.18 KKK19394.1 - 1.5e-05 25.0 12.9 2.7e-05 24.2 12.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Kinesin PF00225.23 KKK19395.1 - 9.7e-112 373.2 2.0 2.7e-111 371.7 2.0 1.8 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KKK19395.1 - 9.3e-24 84.1 0.1 4.7e-23 81.8 0.1 2.3 1 0 0 1 1 1 1 Microtubule binding Microtub_bind PF13931.6 KKK19395.1 - 2.4e-10 40.9 0.5 2.4e-10 40.9 0.5 5.3 4 2 2 6 6 6 1 Kinesin-associated microtubule-binding Baculo_PEP_C PF04513.12 KKK19395.1 - 0.00032 20.8 32.0 0.00036 20.6 0.2 5.8 1 1 2 5 5 5 3 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.12 KKK19395.1 - 0.63 10.1 44.1 0.19 11.8 0.2 7.1 3 2 5 8 8 8 0 Protein of unknown function (DUF1664) HWE_HK PF07536.14 KKK19395.1 - 0.8 10.4 6.6 5.2 7.8 0.2 4.0 3 0 0 3 3 3 0 HWE histidine kinase DUF1515 PF07439.11 KKK19395.1 - 1.1 9.3 15.8 0.3 11.1 2.1 4.9 3 3 0 3 3 3 0 Protein of unknown function (DUF1515) Plasmid_RAQPRD PF09686.10 KKK19395.1 - 3.2 8.0 12.4 4.8 7.5 0.0 5.0 4 1 1 5 5 5 0 Plasmid protein of unknown function (Plasmid_RAQPRD) UPF0183 PF03676.14 KKK19396.1 - 1.9e-49 169.0 0.0 1.9e-31 109.8 0.0 2.9 2 1 0 2 2 2 2 Uncharacterised protein family (UPF0183) zf-ANAPC11 PF12861.7 KKK19397.1 - 7.7e-47 157.3 10.6 8.7e-47 157.1 10.6 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 KKK19397.1 - 1.2e-21 76.8 10.3 1.5e-21 76.4 10.3 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 KKK19397.1 - 1.1e-08 35.2 15.5 3.4e-07 30.5 15.5 2.5 1 1 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KKK19397.1 - 3.5e-05 23.7 9.8 0.00013 21.9 5.5 2.5 2 1 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KKK19397.1 - 8.5e-05 22.3 5.4 8.5e-05 22.3 5.4 2.5 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 KKK19397.1 - 0.0003 20.5 11.3 0.021 14.6 8.7 2.7 1 1 1 2 2 2 1 RING/Ubox like zinc-binding domain zf-C3HC4 PF00097.25 KKK19397.1 - 0.0012 18.6 13.8 0.0046 16.8 13.8 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KKK19397.1 - 0.0012 18.6 12.5 0.002 17.9 7.4 2.3 1 1 2 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KKK19397.1 - 0.0014 18.8 1.8 0.0014 18.8 1.8 2.3 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING FANCL_C PF11793.8 KKK19397.1 - 0.0017 18.5 15.6 0.038 14.2 15.6 3.1 1 1 0 1 1 1 1 FANCL C-terminal domain Prok-RING_4 PF14447.6 KKK19397.1 - 0.014 15.2 2.9 0.014 15.2 2.9 2.5 1 1 2 3 3 3 0 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KKK19397.1 - 0.017 15.1 16.6 0.19 11.7 17.0 2.6 1 1 1 2 2 2 0 zinc-RING finger domain zf-HIT PF04438.16 KKK19397.1 - 0.027 14.4 3.5 0.077 12.9 0.6 2.4 2 0 0 2 2 2 0 HIT zinc finger Rad50_zn_hook PF04423.14 KKK19397.1 - 0.049 13.5 1.3 0.74 9.7 0.0 2.4 2 0 0 2 2 2 0 Rad50 zinc hook motif Zn_ribbon_17 PF17120.5 KKK19397.1 - 0.06 13.0 13.1 0.13 11.9 11.2 2.2 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type YacG PF03884.14 KKK19397.1 - 0.26 11.0 0.3 0.26 11.0 0.3 2.8 3 0 0 3 3 3 0 DNA gyrase inhibitor YacG zf-C2H2_9 PF16293.5 KKK19397.1 - 0.55 10.1 6.1 4.4 7.2 0.1 3.1 2 1 0 2 2 2 0 C2H2 type zinc-finger (1 copy) zf-Nse PF11789.8 KKK19397.1 - 0.57 10.0 5.8 1.1 9.1 5.8 1.6 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit PHD PF00628.29 KKK19397.1 - 0.71 9.8 13.6 3.6 7.6 13.6 2.1 1 1 0 1 1 1 0 PHD-finger zf-RING_11 PF17123.5 KKK19397.1 - 1.9 8.3 13.8 3.2 7.6 10.6 2.7 2 1 0 2 2 2 0 RING-like zinc finger zf-RING-like PF08746.11 KKK19397.1 - 3.8 7.9 12.6 23 5.4 12.6 2.2 1 1 0 1 1 1 0 RING-like domain RINGv PF12906.7 KKK19397.1 - 5.3 7.2 14.8 4.4 7.5 12.3 2.2 1 1 1 2 2 2 0 RING-variant domain RecR PF02132.15 KKK19397.1 - 7.9 6.1 8.0 8.3 6.1 0.1 3.0 3 0 0 3 3 3 0 RecR protein Rhodanese PF00581.20 KKK19399.1 - 5.2e-15 55.9 0.0 2.8e-07 31.0 0.0 2.2 2 0 0 2 2 2 2 Rhodanese-like domain Bac_rhodopsin PF01036.18 KKK19400.1 - 4.5e-34 118.0 15.0 5.2e-34 117.8 15.0 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein PIN_4 PF13638.6 KKK19401.1 - 0.00027 21.2 0.1 0.0053 17.0 0.1 2.5 2 1 0 2 2 2 1 PIN domain YL1 PF05764.13 KKK19401.1 - 0.21 11.7 6.6 0.059 13.5 3.4 1.6 2 0 0 2 2 2 0 YL1 nuclear protein Translin PF01997.16 KKK19402.1 - 1.1e-63 215.0 0.0 1.3e-63 214.7 0.0 1.0 1 0 0 1 1 1 1 Translin family CDC48_2 PF02933.17 KKK19402.1 - 0.072 12.9 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Cell division protein 48 (CDC48), domain 2 RPEL PF02755.15 KKK19403.1 - 4e-19 67.7 9.5 2.6e-10 39.7 2.4 2.5 2 0 0 2 2 2 2 RPEL repeat tRNA-synt_1 PF00133.22 KKK19404.1 - 2.7e-165 551.0 0.0 3.5e-165 550.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KKK19404.1 - 7.4e-22 77.9 1.0 1.4e-21 77.0 1.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 KKK19404.1 - 5.8e-21 74.7 0.0 3.1e-13 49.3 0.0 4.1 3 1 0 3 3 3 3 tRNA synthetases class I (M) zf-FPG_IleRS PF06827.14 KKK19404.1 - 0.00037 20.3 3.4 0.0022 17.8 3.0 2.4 2 0 0 2 2 2 1 Zinc finger found in FPG and IleRS tRNA-synt_1_2 PF13603.6 KKK19404.1 - 0.061 12.8 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 KKK19404.1 - 0.061 12.7 0.0 10 5.4 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain TF_Zn_Ribbon PF08271.12 KKK19404.1 - 0.094 12.2 1.2 0.18 11.4 1.2 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding Lin-8 PF03353.15 KKK19421.1 - 0.63 9.6 5.4 0.83 9.2 5.4 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Exo_endo_phos PF03372.23 KKK19429.1 - 3.4e-19 69.3 0.0 6.3e-19 68.4 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_8 PF13855.6 KKK19429.1 - 3e-15 55.7 23.4 7.4e-08 32.1 5.4 2.2 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 KKK19429.1 - 6.2e-11 42.4 7.2 7.7e-08 32.5 1.5 2.4 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KKK19429.1 - 0.12 13.0 5.7 24 6.0 0.1 4.2 4 0 0 4 4 4 0 Leucine Rich Repeat Glyco_tran_28_C PF04101.16 KKK19450.1 - 7.5e-16 58.6 0.0 4.6e-13 49.5 0.0 2.1 2 0 0 2 2 2 2 Glycosyltransferase family 28 C-terminal domain UDPGT PF00201.18 KKK19450.1 - 0.014 14.2 0.0 0.019 13.8 0.0 1.1 1 0 0 1 1 1 0 UDP-glucoronosyl and UDP-glucosyl transferase OSR1_C PF12202.8 KKK19450.1 - 0.1 12.8 0.0 0.18 12.0 0.0 1.3 1 0 0 1 1 1 0 Oxidative-stress-responsive kinase 1 C-terminal domain Actin PF00022.19 KKK19451.1 - 2.2e-128 428.4 0.0 1.2e-127 425.9 0.0 1.8 1 1 0 1 1 1 1 Actin DUF4332 PF14229.6 KKK19451.1 - 0.16 12.2 0.0 0.3 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4332) DUF3602 PF12223.8 KKK19452.1 - 1e-22 80.5 2.8 4.9e-21 75.1 0.5 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF3602) zf-U1 PF06220.12 KKK19453.1 - 2.5e-16 59.1 2.3 3.3e-16 58.8 2.3 1.2 1 0 0 1 1 1 1 U1 zinc finger Coatomer_E PF04733.14 KKK19453.1 - 0.13 11.7 0.0 0.15 11.5 0.0 1.0 1 0 0 1 1 1 0 Coatomer epsilon subunit SpoU_methylase PF00588.19 KKK19454.1 - 5.4e-25 88.2 0.0 4.5e-24 85.2 0.0 2.2 1 1 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.12 KKK19454.1 - 1.7e-08 34.6 0.0 3.1e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding zf-PHD-like PF15446.6 KKK19455.1 - 3.3e-62 209.0 6.6 9.1e-62 207.6 6.6 1.8 1 0 0 1 1 1 1 PHD/FYVE-zinc-finger like domain SNF2_N PF00176.23 KKK19455.1 - 4.8e-53 180.1 0.1 9e-53 179.2 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-CCCH_6 PF18585.1 KKK19455.1 - 1.2e-24 86.0 0.4 4.3e-24 84.2 0.4 2.1 1 0 0 1 1 1 1 Chromatin remodeling factor Mit1 C-terminal Zn finger 2 Helicase_C PF00271.31 KKK19455.1 - 5.2e-17 62.2 0.0 1.4e-16 60.8 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Chromo PF00385.24 KKK19455.1 - 1.7e-09 37.4 2.5 4.1e-05 23.4 0.5 3.0 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain HDA2-3 PF11496.8 KKK19455.1 - 1.1e-08 34.6 3.2 3e-08 33.2 3.1 1.6 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 PHD PF00628.29 KKK19455.1 - 1.8e-06 27.7 4.0 1.8e-06 27.7 4.0 3.3 2 1 1 3 3 3 1 PHD-finger ResIII PF04851.15 KKK19455.1 - 2.2e-05 24.5 0.0 8.8e-05 22.6 0.0 2.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit C1_1 PF00130.22 KKK19455.1 - 0.0012 18.7 8.4 0.021 14.7 1.9 3.6 3 0 0 3 3 3 1 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF1087 PF06465.13 KKK19455.1 - 0.0071 16.4 1.9 0.023 14.7 1.9 1.9 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1087) NapB PF03892.14 KKK19455.1 - 0.3 11.1 3.3 3.5 7.7 0.2 3.2 3 0 0 3 3 2 0 Nitrate reductase cytochrome c-type subunit (NapB) zf-ANAPC11 PF12861.7 KKK19455.1 - 0.84 9.7 3.9 6.9 6.8 0.4 2.8 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Zf_RING PF16744.5 KKK19455.1 - 0.98 9.6 8.4 1.6 8.9 3.3 2.8 2 0 0 2 2 2 0 KIAA1045 RING finger PHD_2 PF13831.6 KKK19455.1 - 1.6 8.4 11.6 0.098 12.2 3.8 3.0 2 1 0 2 2 2 0 PHD-finger PHD_4 PF16866.5 KKK19455.1 - 7.5 6.7 11.5 16 5.7 3.0 3.6 2 1 0 2 2 2 0 PHD-finger Torus PF16131.5 KKK19456.1 - 0.062 14.0 0.1 0.13 13.0 0.1 1.5 1 0 0 1 1 1 0 Torus domain MRP-S28 PF10213.9 KKK19457.1 - 1.8e-46 157.7 0.0 3.4e-46 156.8 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein CcdA PF07362.12 KKK19457.1 - 0.91 10.0 5.9 13 6.3 0.1 2.9 3 0 0 3 3 3 0 Post-segregation antitoxin CcdA Velvet PF11754.8 KKK19458.1 - 3e-30 106.0 1.2 2.1e-24 86.8 0.2 3.2 2 1 1 3 3 3 2 Velvet factor HMG_box PF00505.19 KKK19460.1 - 1.4e-22 79.8 1.5 2.9e-22 78.9 1.5 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KKK19460.1 - 3.6e-08 33.9 1.7 4.9e-08 33.4 0.7 1.8 2 0 0 2 2 2 1 HMG-box domain Lipase_GDSL PF00657.22 KKK19461.1 - 9.3e-06 25.8 0.0 1.2e-05 25.4 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 KKK19461.1 - 0.00021 21.8 0.2 0.00032 21.2 0.2 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family CDPS PF16715.5 KKK19461.1 - 0.095 12.3 0.0 0.57 9.8 0.0 2.1 1 1 1 2 2 2 0 Cyclodipeptide synthase AAA_18 PF13238.6 KKK19462.1 - 0.0019 18.7 0.0 0.018 15.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain PRK PF00485.18 KKK19462.1 - 0.0071 16.1 0.0 0.013 15.3 0.0 1.4 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_16 PF13191.6 KKK19462.1 - 0.0087 16.5 0.1 0.02 15.3 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.27 KKK19462.1 - 0.051 14.1 0.0 0.095 13.2 0.0 1.4 1 0 0 1 1 1 0 ABC transporter CPT PF07931.12 KKK19462.1 - 0.083 12.7 0.1 0.23 11.3 0.1 1.7 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Rad17 PF03215.15 KKK19462.1 - 0.1 12.5 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain Mg_chelatase PF01078.21 KKK19462.1 - 0.13 11.6 0.0 0.25 10.7 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 KKK19462.1 - 0.31 11.2 1.4 1.2 9.3 1.4 1.9 1 1 0 1 1 1 0 AAA domain SNF2_N PF00176.23 KKK19463.1 - 3.9e-37 127.8 0.0 2.2e-33 115.5 0.0 2.2 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 KKK19463.1 - 5.3e-09 36.4 0.1 1e-08 35.5 0.1 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Ribosomal_S6e PF01092.19 KKK19464.1 - 1.1e-54 183.7 1.5 1.8e-54 183.0 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein S6e UFD1 PF03152.14 KKK19468.1 - 6.2e-75 250.4 0.0 7.7e-75 250.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 Oxidored_FMN PF00724.20 KKK19469.1 - 2.2e-58 198.2 0.0 5.7e-57 193.5 0.0 2.1 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family GYF PF02213.16 KKK19470.1 - 3.6e-13 49.0 1.1 9.5e-13 47.6 1.1 1.7 1 0 0 1 1 1 1 GYF domain HBS1_N PF08938.10 KKK19470.1 - 0.039 14.2 3.6 0.17 12.2 3.6 2.1 1 0 0 1 1 1 0 HBS1 N-terminus TIP49 PF06068.13 KKK19471.1 - 1.7e-153 511.0 1.8 2.1e-153 510.6 1.8 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 KKK19471.1 - 1.9e-21 76.0 0.4 5.8e-21 74.4 0.4 1.9 1 0 0 1 1 1 1 TIP49 AAA-lid domain AAA PF00004.29 KKK19471.1 - 1e-08 35.7 1.3 1.9e-05 25.1 0.0 2.9 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KKK19471.1 - 1.1e-07 31.7 0.7 7.4e-05 22.5 0.0 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KKK19471.1 - 1.4e-06 28.8 0.2 7.8e-06 26.4 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain DnaB_C PF03796.15 KKK19471.1 - 2.7e-06 26.9 1.0 5.2e-06 26.0 1.0 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain Mg_chelatase PF01078.21 KKK19471.1 - 0.00086 18.7 0.9 0.012 15.0 0.5 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KKK19471.1 - 0.0032 17.5 0.2 0.46 10.5 0.0 3.0 2 1 1 3 3 3 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KKK19471.1 - 0.0063 16.8 0.0 0.66 10.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 KKK19471.1 - 0.01 15.6 0.1 4.9 6.8 0.1 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_19 PF13245.6 KKK19471.1 - 0.032 14.6 2.2 0.57 10.5 1.7 2.8 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 KKK19471.1 - 0.039 13.5 0.1 0.089 12.4 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 KKK19471.1 - 0.046 13.5 0.6 0.14 11.9 0.6 1.9 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KKK19471.1 - 0.055 13.6 0.0 0.16 12.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 KKK19471.1 - 0.083 12.0 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_7 PF12775.7 KKK19471.1 - 0.09 12.3 0.3 0.37 10.3 0.0 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_28 PF13521.6 KKK19471.1 - 0.12 12.7 0.0 0.29 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain Abhydrolase_1 PF00561.20 KKK19472.1 - 2e-22 80.1 0.1 6.8e-17 62.0 0.1 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KKK19472.1 - 1.6e-12 48.5 0.0 2.1e-12 48.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KKK19472.1 - 9.5e-09 34.9 0.1 1.3e-08 34.4 0.1 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 KKK19472.1 - 2.8e-07 30.5 0.3 1.8e-05 24.6 0.3 2.2 1 1 0 1 1 1 1 PGAP1-like protein Thioesterase PF00975.20 KKK19472.1 - 0.00014 22.1 0.0 0.00021 21.5 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain DUF915 PF06028.11 KKK19472.1 - 0.00033 20.1 0.1 0.75 9.1 0.0 2.8 2 1 1 3 3 3 2 Alpha/beta hydrolase of unknown function (DUF915) Esterase PF00756.20 KKK19472.1 - 0.002 17.8 0.0 0.0055 16.4 0.0 1.8 1 1 0 1 1 1 1 Putative esterase Chlorophyllase2 PF12740.7 KKK19472.1 - 0.0056 15.6 0.0 0.017 14.0 0.0 1.7 2 0 0 2 2 2 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 KKK19472.1 - 0.0068 15.5 0.1 0.016 14.3 0.1 1.7 1 1 0 1 1 1 1 Chlorophyllase DUF676 PF05057.14 KKK19472.1 - 0.008 15.7 0.1 0.012 15.1 0.1 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_3 PF07859.13 KKK19472.1 - 0.014 15.2 0.0 0.019 14.8 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF3530 PF12048.8 KKK19472.1 - 0.031 13.7 0.0 0.04 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) UPF0227 PF05728.12 KKK19472.1 - 0.034 14.1 0.0 0.05 13.6 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Ndr PF03096.14 KKK19472.1 - 0.07 11.8 0.0 0.14 10.8 0.0 1.6 2 0 0 2 2 2 0 Ndr family Abhydrolase_2 PF02230.16 KKK19472.1 - 0.1 12.4 0.1 11 5.7 0.0 2.3 1 1 0 2 2 2 0 Phospholipase/Carboxylesterase Lipase_3 PF01764.25 KKK19472.1 - 0.13 12.1 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DUF2048 PF09752.9 KKK19472.1 - 0.14 11.2 0.0 0.29 10.2 0.0 1.5 2 0 0 2 2 2 0 Abhydrolase domain containing 18 Abhydrolase_5 PF12695.7 KKK19472.1 - 0.18 11.6 0.0 0.33 10.7 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family adh_short PF00106.25 KKK19474.1 - 2.3e-29 102.3 0.0 3e-29 101.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KKK19474.1 - 7.8e-26 91.1 0.0 1.8e-25 89.9 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KKK19474.1 - 0.0021 18.0 0.0 0.0048 16.8 0.0 1.6 2 0 0 2 2 2 1 KR domain ADH_zinc_N PF00107.26 KKK19474.1 - 0.0042 17.1 0.1 0.29 11.1 0.0 2.3 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Epimerase PF01370.21 KKK19474.1 - 0.041 13.3 0.0 0.06 12.8 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.19 KKK19474.1 - 0.11 11.8 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain RNA_pol_Rpb2_6 PF00562.28 KKK19475.1 - 1e-121 406.7 0.1 1.5e-121 406.2 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 KKK19475.1 - 2.7e-54 183.8 0.4 4.1e-54 183.2 0.4 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_4 PF04566.13 KKK19475.1 - 9.2e-24 83.5 1.6 2.4e-23 82.2 0.5 2.3 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_2 PF04561.14 KKK19475.1 - 3.8e-22 78.9 4.7 8.8e-22 77.7 4.7 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_3 PF04565.16 KKK19475.1 - 1.3e-19 70.1 0.0 4.1e-19 68.5 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_7 PF04560.20 KKK19475.1 - 5.3e-18 65.2 0.5 1.5e-17 63.8 0.5 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_5 PF04567.17 KKK19475.1 - 1.2e-10 41.8 0.4 3.6e-10 40.3 0.4 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 NRDD PF13597.6 KKK19475.1 - 0.13 11.0 0.1 0.22 10.3 0.1 1.2 1 0 0 1 1 1 0 Anaerobic ribonucleoside-triphosphate reductase Sugar_tr PF00083.24 KKK19476.1 - 2e-78 264.3 26.8 2.8e-65 221.0 11.7 2.8 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KKK19476.1 - 1.2e-24 87.0 32.8 3.3e-10 39.4 5.2 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily OATP PF03137.20 KKK19476.1 - 5.1e-06 25.1 5.6 0.00012 20.5 1.2 2.8 2 1 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family DUF2781 PF10914.8 KKK19476.1 - 0.94 9.9 7.9 0.18 12.2 1.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2781) DUF676 PF05057.14 KKK19482.1 - 3.1e-41 141.3 0.0 1.2e-36 126.3 0.0 3.2 1 1 0 1 1 1 1 Putative serine esterase (DUF676) LCAT PF02450.15 KKK19482.1 - 0.061 12.5 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DUF915 PF06028.11 KKK19482.1 - 0.065 12.6 0.1 0.12 11.7 0.1 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) PGAP1 PF07819.13 KKK19482.1 - 0.084 12.6 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Inositol_P PF00459.25 KKK19483.1 - 1.8e-70 237.6 0.0 2e-70 237.4 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family TFIIF_alpha PF05793.12 KKK19484.1 - 1.7e-06 26.9 69.1 6.7e-06 25.0 57.7 4.1 1 1 2 3 3 3 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF383 PF04063.14 KKK19485.1 - 2.6e-68 229.5 0.2 2.9e-67 226.0 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF383) DUF384 PF04064.13 KKK19485.1 - 1.5e-23 82.4 1.8 2.7e-23 81.5 0.8 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF384) AsiA PF09010.10 KKK19485.1 - 0.018 15.2 0.0 0.036 14.2 0.0 1.5 1 0 0 1 1 1 0 Anti-Sigma Factor A Melibiase PF02065.18 KKK19487.1 - 2.9e-145 483.6 0.0 3.7e-145 483.2 0.0 1.1 1 0 0 1 1 1 1 Melibiase Glyco_hydro_36N PF16875.5 KKK19487.1 - 4.1e-82 275.6 0.0 5.5e-82 275.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 36 N-terminal domain Glyco_hydro_36C PF16874.5 KKK19487.1 - 7.9e-20 71.1 0.0 1.6e-19 70.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 36 C-terminal domain GHL10 PF02638.15 KKK19487.1 - 0.00021 20.5 0.0 0.00032 19.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase-like 10 GMC_oxred_N PF00732.19 KKK19488.1 - 1.1e-60 205.6 0.0 1.5e-60 205.1 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KKK19488.1 - 3e-32 112.1 0.4 8.6e-32 110.6 0.2 1.9 2 0 0 2 2 2 1 GMC oxidoreductase Lycopene_cycl PF05834.12 KKK19488.1 - 5.8e-05 22.3 0.1 0.00012 21.3 0.1 1.5 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 KKK19488.1 - 0.00047 19.4 0.2 0.11 11.6 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 KKK19488.1 - 0.0096 15.5 0.5 0.025 14.2 0.5 1.7 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 KKK19488.1 - 0.0099 15.1 0.1 0.041 13.1 0.1 2.0 2 0 0 2 2 2 1 Thi4 family Pyr_redox_3 PF13738.6 KKK19488.1 - 0.02 14.2 0.7 2.9 7.1 0.5 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KKK19488.1 - 0.02 15.1 0.0 0.046 13.9 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KKK19488.1 - 0.047 12.9 0.1 0.37 10.0 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF3837 PF12939.7 KKK19488.1 - 0.12 12.7 0.1 0.88 10.0 0.2 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF3837) TrkA_N PF02254.18 KKK19488.1 - 0.21 11.8 0.5 0.67 10.2 0.1 2.1 3 0 0 3 3 3 0 TrkA-N domain MFS_1 PF07690.16 KKK19489.1 - 2.1e-33 115.7 31.0 2.9e-33 115.2 31.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Claudin_2 PF13903.6 KKK19489.1 - 3 7.6 7.8 2.3 7.9 2.4 2.7 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction 3HCDH_N PF02737.18 KKK19490.1 - 1.8e-24 86.6 0.0 2.9e-24 85.9 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 KKK19490.1 - 4e-19 69.0 0.0 6.3e-19 68.4 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain ApbA PF02558.16 KKK19490.1 - 0.015 14.9 0.0 0.023 14.3 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.18 KKK19490.1 - 0.022 15.0 0.0 0.062 13.6 0.0 1.8 1 1 0 1 1 1 0 TrkA-N domain AlaDh_PNT_C PF01262.21 KKK19490.1 - 0.093 12.0 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Adenine_glyco PF03352.13 KKK19491.1 - 0.098 12.4 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Methyladenine glycosylase Glyco_hydro_31 PF01055.26 KKK19492.1 - 5.7e-90 302.6 0.7 8.2e-90 302.1 0.7 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 KKK19492.1 - 9.3e-13 48.3 0.1 2.9e-12 46.7 0.1 1.9 1 0 0 1 1 1 1 Galactose mutarotase-like DUF5110 PF17137.4 KKK19492.1 - 0.013 15.7 0.0 0.032 14.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5110) MFS_1 PF07690.16 KKK19493.1 - 1.2e-29 103.3 29.0 1.5e-29 103.0 27.9 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Glyco_hydro_11 PF00457.17 KKK19495.1 - 2.7e-77 258.4 21.2 3.1e-77 258.2 21.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 Fungal_trans PF04082.18 KKK19496.1 - 1.3e-08 34.2 0.0 2.5e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK19496.1 - 1.6e-05 24.9 6.7 3.6e-05 23.8 6.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dioxygenase_C PF00775.21 KKK19497.1 - 1.1e-39 135.7 0.0 1.5e-39 135.4 0.0 1.1 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 KKK19497.1 - 2.7e-24 84.8 0.0 4.5e-24 84.1 0.0 1.4 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.6 KKK19497.1 - 0.19 12.0 0.0 0.64 10.3 0.0 1.8 1 1 0 1 1 1 0 Carboxypeptidase regulatory-like domain Abhydrolase_1 PF00561.20 KKK19498.1 - 4.2e-15 56.1 0.0 5e-15 55.8 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KKK19498.1 - 2.9e-06 28.0 0.8 4.2e-06 27.5 0.8 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KKK19498.1 - 0.00021 20.6 0.0 0.0003 20.1 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 CTV_P6 PF06706.11 KKK19499.1 - 1.4 8.7 8.5 1.3 8.8 5.1 2.6 2 0 0 2 2 2 0 Citrus tristeza virus 6-kDa protein TPR_2 PF07719.17 KKK19507.1 - 3.7e-06 26.6 2.7 0.02 15.0 0.2 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 KKK19507.1 - 6.2e-06 25.8 1.1 0.062 13.1 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 KKK19507.1 - 0.024 15.3 1.4 0.06 14.0 0.3 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Fungal_trans PF04082.18 KKK19508.1 - 1.8e-09 37.0 0.0 3.1e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF2841 PF11001.8 KKK19509.1 - 2.9e-48 163.0 0.9 4.5e-48 162.4 0.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) SSXT PF05030.12 KKK19510.1 - 1.3e-05 24.7 0.0 0.21 11.3 0.0 2.3 2 0 0 2 2 2 2 SSXT protein (N-terminal region) DUF1179 PF06678.11 KKK19510.1 - 5.6 7.0 7.0 6.5 6.8 3.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1179) Ribosomal_S13 PF00416.22 KKK19511.1 - 3.8e-13 50.0 0.1 4.3e-13 49.8 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 HHH_6 PF14579.6 KKK19511.1 - 0.08 13.2 0.0 0.083 13.2 0.0 1.1 1 0 0 1 1 1 0 Helix-hairpin-helix motif peroxidase PF00141.23 KKK19513.1 - 2e-45 155.3 0.0 2.9e-45 154.7 0.0 1.2 1 0 0 1 1 1 1 Peroxidase APG5 PF04106.12 KKK19514.1 - 0.073 12.6 0.1 0.076 12.6 0.1 1.1 1 0 0 1 1 1 0 Autophagy protein Apg5 PDZ_1 PF12812.7 KKK19515.1 - 3.6e-53 177.5 0.0 5.5e-34 116.0 0.0 2.5 2 0 0 2 2 2 2 PDZ-like domain Trypsin_2 PF13365.6 KKK19515.1 - 1.7e-26 93.9 0.8 2.4e-22 80.4 0.0 2.9 3 0 0 3 3 3 2 Trypsin-like peptidase domain PDZ_6 PF17820.1 KKK19515.1 - 9.2e-21 73.4 0.7 6.4e-09 35.5 0.5 4.7 4 1 0 4 4 4 3 PDZ domain PDZ_2 PF13180.6 KKK19515.1 - 8.2e-13 48.5 0.1 5.6e-05 23.4 0.0 4.3 5 0 0 5 5 5 3 PDZ domain PDZ PF00595.24 KKK19515.1 - 9.6e-12 45.1 0.0 8.7e-05 22.8 0.0 3.6 3 0 0 3 3 3 3 PDZ domain Tricorn_PDZ PF14685.6 KKK19515.1 - 0.00029 20.7 0.5 0.24 11.4 0.2 3.8 3 0 0 3 3 3 1 Tricorn protease PDZ domain 4HPAD_g_N PF18671.1 KKK19515.1 - 0.069 12.9 0.0 0.26 11.0 0.0 2.0 1 0 0 1 1 1 0 4-Hydroxyphenylacetate decarboxylase subunit gamma N-terminal Peptidase_S46 PF10459.9 KKK19515.1 - 0.079 11.6 0.1 0.15 10.7 0.1 1.3 1 0 0 1 1 1 0 Peptidase S46 DUF31 PF01732.16 KKK19515.1 - 0.12 11.9 0.3 0.19 11.3 0.3 1.2 1 0 0 1 1 1 0 Putative peptidase (DUF31) Pup PF05639.11 KKK19515.1 - 0.14 13.1 0.0 1.1 10.3 0.0 2.3 2 0 0 2 2 2 0 Pup-like protein Cyclase PF04199.13 KKK19516.1 - 2.2e-11 44.2 0.0 3.6e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 Putative cyclase GFO_IDH_MocA PF01408.22 KKK19517.1 - 6.6e-25 88.3 0.6 1e-23 84.4 0.2 2.2 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 KKK19517.1 - 1.1e-05 26.0 0.4 2.7e-05 24.8 0.2 1.8 2 0 0 2 2 2 1 Homoserine dehydrogenase, NAD binding domain Claudin_2 PF13903.6 KKK19518.1 - 0.0082 15.9 1.2 0.0082 15.9 1.2 2.4 1 1 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction COX7C PF02935.16 KKK19518.1 - 0.023 15.0 0.6 2 8.7 0.1 2.9 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VIIc RTA1 PF04479.13 KKK19518.1 - 0.03 13.9 8.8 0.031 13.9 7.8 1.6 1 1 0 1 1 1 0 RTA1 like protein K1 PF02960.14 KKK19518.1 - 0.044 13.9 0.1 0.085 13.0 0.1 1.4 1 0 0 1 1 1 0 K1 glycoprotein CPBP PF02517.16 KKK19518.1 - 6.3 7.2 10.9 1.3e+02 3.0 10.9 2.7 1 1 0 1 1 1 0 CPBP intramembrane metalloprotease PspC PF04024.12 KKK19518.1 - 9.4 6.2 18.8 1 9.2 1.9 3.8 3 2 0 3 3 3 0 PspC domain Fungal_trans_2 PF11951.8 KKK19519.1 - 1.6e-08 33.8 0.8 2.1e-08 33.4 0.8 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK19519.1 - 4.8e-06 26.6 10.6 1.1e-05 25.4 10.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GFO_IDH_MocA PF01408.22 KKK19520.1 - 3.9e-18 66.4 0.0 7.8e-18 65.4 0.0 1.5 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold Sugar_tr PF00083.24 KKK19521.1 - 4.4e-73 246.7 28.2 5.4e-73 246.4 28.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKK19521.1 - 1.4e-21 76.8 43.3 1.4e-19 70.2 32.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily PX PF00787.24 KKK19523.1 - 3.7e-18 65.6 0.3 8.9e-18 64.3 0.3 1.7 1 0 0 1 1 1 1 PX domain Tmemb_cc2 PF10267.9 KKK19523.1 - 0.0046 16.2 0.9 0.0077 15.4 0.9 1.3 1 0 0 1 1 1 1 Predicted transmembrane and coiled-coil 2 protein Prefoldin_3 PF13758.6 KKK19523.1 - 0.077 13.1 0.2 0.077 13.1 0.2 2.5 3 0 0 3 3 3 0 Prefoldin subunit V-SNARE_C PF12352.8 KKK19523.1 - 0.13 12.6 0.1 0.35 11.2 0.1 1.7 1 0 0 1 1 1 0 Snare region anchored in the vesicle membrane C-terminus Nha1_C PF08619.10 KKK19524.1 - 9.9e-94 315.2 18.7 2.1e-93 314.1 18.7 1.4 1 1 0 1 1 1 1 Alkali metal cation/H+ antiporter Nha1 C terminus Na_H_Exchanger PF00999.21 KKK19524.1 - 2.9e-78 263.3 18.4 3.5e-78 263.1 18.4 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Anillin_N PF16018.5 KKK19524.1 - 0.06 14.0 2.1 0.12 13.0 0.3 2.5 2 0 0 2 2 2 0 Anillin N-terminus DUF21 PF01595.20 KKK19524.1 - 0.39 10.4 8.3 0.034 13.9 2.4 2.1 2 0 0 2 2 2 0 Cyclin M transmembrane N-terminal domain SAM_2 PF07647.17 KKK19525.1 - 5.9e-16 58.3 0.0 1.7e-15 56.9 0.0 1.8 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KKK19525.1 - 4.5e-12 46.2 0.0 1.5e-11 44.5 0.0 1.8 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) RA PF00788.23 KKK19525.1 - 5.3e-12 46.2 0.0 1.1e-11 45.2 0.0 1.4 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SAM_4 PF18017.1 KKK19525.1 - 0.012 15.5 0.0 0.021 14.8 0.0 1.3 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Inositol_P PF00459.25 KKK19529.1 - 3e-38 131.9 0.2 9.6e-38 130.2 0.2 1.7 1 1 0 1 1 1 1 Inositol monophosphatase family DNA_ligase_IV PF11411.8 KKK19530.1 - 8 6.7 7.2 0.68 10.1 2.7 1.6 2 0 0 2 2 2 0 DNA ligase IV Peptidase_M28 PF04389.17 KKK19531.1 - 6.3e-31 107.6 0.3 8.8e-31 107.1 0.3 1.2 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 KKK19531.1 - 1.8e-06 27.8 0.1 3.7e-06 26.8 0.1 1.6 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 PTAC PF06130.12 KKK19531.1 - 0.32 11.2 2.0 0.63 10.2 0.3 2.2 2 0 0 2 2 2 0 Phosphate propanoyltransferase R3H-assoc PF13902.6 KKK19532.1 - 1.1e-20 74.4 6.8 4.7e-20 72.3 6.4 2.3 1 1 0 1 1 1 1 R3H-associated N-terminal domain R3H PF01424.22 KKK19532.1 - 0.0013 18.6 0.1 0.1 12.6 0.0 2.6 2 1 0 2 2 2 2 R3H domain PP2C PF00481.21 KKK19533.1 - 5e-52 177.1 0.0 8.1e-52 176.4 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_8 PF13855.6 KKK19533.1 - 8.8e-30 102.3 61.6 2.3e-06 27.2 1.2 10.5 7 4 4 11 11 11 9 Leucine rich repeat Guanylate_cyc PF00211.20 KKK19533.1 - 2.4e-28 99.0 0.0 5e-28 98.0 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain LRR_4 PF12799.7 KKK19533.1 - 6.6e-25 86.8 58.2 0.00039 20.8 1.3 12.4 10 1 3 13 13 13 10 Leucine Rich repeats (2 copies) Ad_cyc_g-alpha PF08509.11 KKK19533.1 - 3.8e-08 32.9 0.0 1.5e-07 31.0 0.0 2.0 1 0 0 1 1 1 1 Adenylate cyclase G-alpha binding domain LRR_9 PF14580.6 KKK19533.1 - 6.6e-08 32.3 17.6 0.0048 16.4 0.1 4.8 2 1 3 5 5 5 4 Leucine-rich repeat LRR_5 PF13306.6 KKK19533.1 - 0.0092 15.9 5.4 2.9 7.9 0.0 4.7 5 1 0 5 5 5 1 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 KKK19533.1 - 0.27 11.9 55.1 3.8 8.4 0.1 13.6 14 2 1 15 15 15 0 Leucine Rich Repeat Zn_clus PF00172.18 KKK19534.1 - 3.7e-07 30.1 9.3 5.5e-07 29.6 9.3 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MSC PF09402.10 KKK19535.1 - 5.7e-107 358.1 0.0 8.3e-107 357.5 0.0 1.2 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain HeH PF12949.7 KKK19535.1 - 4.2e-17 61.6 0.2 7.4e-17 60.8 0.2 1.4 1 0 0 1 1 1 1 HeH/LEM domain IMS PF00817.20 KKK19536.1 - 2.2e-41 141.4 0.0 3.9e-41 140.5 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 KKK19536.1 - 2.6e-14 53.9 0.0 6.9e-14 52.6 0.0 1.7 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain UBM PF14377.6 KKK19536.1 - 1.3e-10 40.3 11.2 2.6e-08 33.0 0.3 4.0 4 0 0 4 4 4 2 Ubiquitin binding region BRCT_2 PF16589.5 KKK19536.1 - 4e-08 33.6 0.0 9.7e-08 32.3 0.0 1.7 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain IMS_HHH PF11798.8 KKK19536.1 - 2.1e-05 24.5 0.1 0.00012 22.2 0.0 2.3 2 0 0 2 2 2 1 IMS family HHH motif LIG3_BRCT PF16759.5 KKK19536.1 - 0.0011 19.2 0.0 0.002 18.4 0.0 1.4 1 0 0 1 1 1 1 DNA ligase 3 BRCT domain mCpol PF18182.1 KKK19536.1 - 0.0012 19.1 0.1 0.0026 18.1 0.1 1.5 1 0 0 1 1 1 1 minimal CRISPR polymerase domain BRCT PF00533.26 KKK19536.1 - 0.0017 18.7 0.0 0.006 16.9 0.0 1.9 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 KKK19536.1 - 0.0061 16.5 0.0 0.013 15.4 0.0 1.6 1 0 0 1 1 1 1 twin BRCT domain Cdd1 PF11731.8 KKK19536.1 - 0.011 16.0 0.1 0.054 13.7 0.0 2.2 2 0 0 2 2 2 0 Pathogenicity locus AT_hook PF02178.19 KKK19536.1 - 2.1 8.5 6.6 9.3 6.5 6.6 2.2 1 0 0 1 1 1 0 AT hook motif Fungal_trans PF04082.18 KKK19537.1 - 1.5e-19 70.1 0.0 4.6e-17 61.9 0.0 2.4 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK19537.1 - 4.9e-08 33.0 7.9 4.9e-08 33.0 7.9 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HEAT_EZ PF13513.6 KKK19569.1 - 1.4e-28 98.9 14.4 3.9e-15 56.0 0.1 10.2 8 2 3 11 11 10 6 HEAT-like repeat HEAT PF02985.22 KKK19569.1 - 6.4e-25 85.1 18.0 2.6e-05 24.1 0.0 12.1 13 0 0 13 13 13 4 HEAT repeat HEAT_2 PF13646.6 KKK19569.1 - 1.9e-15 57.0 2.6 0.0063 16.9 0.0 8.6 6 3 3 9 9 9 2 HEAT repeats Cnd1 PF12717.7 KKK19569.1 - 1e-12 48.4 0.0 0.0015 18.6 0.0 5.3 3 1 1 5 5 5 3 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 KKK19569.1 - 8.1e-08 31.3 0.3 0.00013 20.7 0.0 3.5 2 1 1 3 3 3 2 Adaptin N terminal region MMS19_C PF12460.8 KKK19569.1 - 1.8e-07 30.7 1.0 0.23 10.6 0.0 5.0 4 1 0 5 5 5 3 RNAPII transcription regulator C-terminal Vac14_Fab1_bd PF12755.7 KKK19569.1 - 9e-07 29.4 0.0 0.54 10.9 0.0 6.3 4 3 3 7 7 7 1 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 KKK19569.1 - 1e-05 25.2 0.5 30 4.1 0.0 6.6 5 2 2 7 7 7 0 CLASP N terminal IBN_N PF03810.19 KKK19569.1 - 9.1e-05 22.3 0.2 0.014 15.2 0.0 4.2 2 1 1 3 3 3 1 Importin-beta N-terminal domain Arm PF00514.23 KKK19569.1 - 0.0001 22.2 0.4 1.5 9.0 0.0 5.1 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat Xpo1 PF08389.12 KKK19569.1 - 0.00027 21.0 0.7 2.5 8.2 0.0 4.8 4 1 1 5 5 5 1 Exportin 1-like protein DUF3437 PF11919.8 KKK19569.1 - 0.0025 17.7 0.0 0.27 11.2 0.0 3.8 4 0 0 4 4 4 1 Domain of unknown function (DUF3437) HEAT_PBS PF03130.16 KKK19569.1 - 0.0056 17.2 2.0 14 6.7 0.0 5.3 5 0 0 5 5 4 0 PBS lyase HEAT-like repeat RIX1 PF08167.12 KKK19569.1 - 0.062 13.0 0.2 5.2 6.8 0.0 3.9 5 0 0 5 5 5 0 rRNA processing/ribosome biogenesis Cohesin_HEAT PF12765.7 KKK19569.1 - 0.081 13.2 0.0 15 6.0 0.0 4.2 5 0 0 5 5 4 0 HEAT repeat associated with sister chromatid cohesion TIP120 PF08623.10 KKK19569.1 - 0.15 11.9 0.0 43 3.8 0.0 3.8 4 0 0 4 4 4 0 TATA-binding protein interacting (TIP20) DUF1708 PF08101.11 KKK19569.1 - 0.19 10.8 0.0 0.35 10.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1708) Syja_N PF02383.18 KKK19570.1 - 1.8e-93 313.3 0.0 2.7e-93 312.8 0.0 1.3 1 0 0 1 1 1 1 SacI homology domain hSac2 PF12456.8 KKK19570.1 - 2.2e-39 133.7 0.0 5.5e-39 132.4 0.0 1.7 1 0 0 1 1 1 1 Inositol phosphatase Ribosomal_S3Ae PF01015.18 KKK19571.1 - 1.4e-49 168.5 0.4 1.5e-49 168.3 0.4 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family SUI1 PF01253.22 KKK19571.1 - 0.015 15.9 0.0 0.022 15.3 0.0 1.3 1 0 0 1 1 1 0 Translation initiation factor SUI1 NEMO PF11577.8 KKK19571.1 - 0.092 12.8 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 NF-kappa-B essential modulator NEMO Cation_ATPase_C PF00689.21 KKK19580.1 - 3e-47 160.7 10.0 3e-47 160.7 10.0 2.0 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 KKK19580.1 - 7.8e-38 129.8 0.2 7.8e-38 129.8 0.2 2.4 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase PF13246.6 KKK19580.1 - 1.5e-20 73.1 0.0 2.7e-20 72.2 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KKK19580.1 - 6.3e-17 62.6 0.0 1.7e-16 61.2 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KKK19580.1 - 9.3e-08 31.7 0.8 1.5e-06 27.8 0.1 2.6 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KKK19580.1 - 0.0002 21.2 0.1 0.0021 17.9 0.1 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase K_oxygenase PF13434.6 KKK19581.1 - 2.4e-10 40.1 0.0 5.8e-05 22.4 0.0 3.3 4 0 0 4 4 4 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 KKK19581.1 - 4e-05 23.0 0.0 0.016 14.5 0.0 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KKK19581.1 - 0.00076 18.8 0.0 0.64 9.2 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KKK19581.1 - 0.0013 18.7 0.0 0.48 10.4 0.2 2.9 3 1 0 3 3 3 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 KKK19581.1 - 0.0033 16.7 0.0 0.01 15.1 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 KKK19581.1 - 0.025 14.8 0.0 0.079 13.2 0.0 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Herpes_UL56 PF04534.12 KKK19581.1 - 0.025 14.1 0.0 0.045 13.3 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus UL56 protein GIDA PF01134.22 KKK19581.1 - 0.082 12.0 0.0 0.36 9.9 0.0 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A DAO PF01266.24 KKK19581.1 - 0.1 12.2 5.3 1.3 8.5 5.2 2.5 1 1 0 1 1 1 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KKK19581.1 - 0.13 11.3 0.0 0.27 10.2 0.0 1.5 2 0 0 2 2 2 0 Lycopene cyclase protein HI0933_like PF03486.14 KKK19581.1 - 0.25 10.0 0.0 0.86 8.2 0.0 1.8 2 0 0 2 2 2 0 HI0933-like protein HMG_CoA_synt_C PF08540.10 KKK19583.1 - 1.5e-106 356.1 0.8 2.2e-106 355.6 0.8 1.3 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.17 KKK19583.1 - 4.1e-96 319.8 0.1 6.3e-96 319.2 0.1 1.3 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal TFR_dimer PF04253.15 KKK19584.1 - 3.9e-37 127.0 0.1 7.6e-37 126.1 0.1 1.5 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 KKK19584.1 - 3.2e-16 59.6 0.0 8e-16 58.3 0.0 1.7 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 KKK19584.1 - 8.4e-15 54.6 0.0 1.5e-14 53.8 0.0 1.4 1 0 0 1 1 1 1 PA domain PKI PF02827.16 KKK19584.1 - 0.1 12.9 0.4 0.23 11.7 0.4 1.5 1 0 0 1 1 1 0 cAMP-dependent protein kinase inhibitor DUF1765 PF08578.10 KKK19585.1 - 1.6e-43 148.1 7.8 6.1e-43 146.3 7.7 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1765) HtrL_YibB PF09612.10 KKK19607.1 - 0.049 13.2 0.2 0.066 12.7 0.2 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (HtrL_YibB) Glyco_hydro_75 PF07335.11 KKK19608.1 - 4e-41 141.0 0.1 5.7e-41 140.5 0.1 1.2 1 0 0 1 1 1 1 Fungal chitosanase of glycosyl hydrolase group 75 Glyco_hydro_61 PF03443.14 KKK19608.1 - 0.015 15.3 0.1 0.025 14.5 0.1 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 61 Nup96 PF12110.8 KKK19609.1 - 5.8e-84 281.6 1.1 1e-83 280.9 1.1 1.4 1 0 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.14 KKK19609.1 - 1.2e-48 165.1 0.0 2.2e-48 164.2 0.0 1.5 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.6 KKK19609.1 - 1.3e-10 42.0 177.3 1.2e-06 29.2 41.6 11.5 4 2 6 10 10 10 4 Nucleoporin FG repeat region AMP-binding_C PF13193.6 KKK19610.1 - 1.8e-26 92.9 0.6 2.5e-26 92.4 0.6 1.2 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.28 KKK19610.1 - 0.0012 17.5 0.4 0.0023 16.6 0.4 1.5 1 0 0 1 1 1 1 AMP-binding enzyme SAPS PF04499.15 KKK19611.1 - 4.9e-205 682.0 0.3 3.7e-203 675.8 0.0 2.9 3 1 0 3 3 3 1 SIT4 phosphatase-associated protein DUF4484 PF14831.6 KKK19611.1 - 5.7 6.9 7.2 4.4 7.3 1.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4484) MFS_1 PF07690.16 KKK19612.1 - 4.2e-51 173.9 26.1 1.6e-43 149.0 19.4 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KKK19612.1 - 1.2e-06 27.7 32.9 4.2e-06 25.9 12.5 3.7 3 1 1 4 4 4 4 Sugar (and other) transporter OATP PF03137.20 KKK19612.1 - 0.22 9.7 8.5 0.1 10.9 3.2 2.3 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family DUF3391 PF11871.8 KKK19612.1 - 0.24 11.9 1.6 2.1 8.9 1.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) Complex1_51K PF01512.17 KKK19613.1 - 1.8e-45 154.5 0.0 3e-45 153.8 0.0 1.4 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 KKK19613.1 - 1.6e-28 98.6 0.3 4e-28 97.3 0.3 1.7 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.9 KKK19613.1 - 3.1e-08 33.4 0.0 8.4e-08 32.0 0.0 1.8 1 0 0 1 1 1 1 SLBB domain SET PF00856.28 KKK19613.1 - 0.00015 22.2 0.0 0.00029 21.3 0.0 1.5 1 0 0 1 1 1 1 SET domain DUF3568 PF12092.8 KKK19613.1 - 1.1 9.3 2.5 0.99 9.5 0.9 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3568) Forkhead PF00250.18 KKK19614.1 - 3.8e-36 123.2 1.4 6.8e-36 122.4 1.4 1.4 1 0 0 1 1 1 1 Forkhead domain FHA PF00498.26 KKK19614.1 - 6.6e-08 32.8 0.0 1.5e-07 31.7 0.0 1.6 1 0 0 1 1 1 1 FHA domain TENA_THI-4 PF03070.16 KKK19615.1 - 6.9e-05 22.8 0.0 0.00019 21.3 0.0 1.8 1 1 0 1 1 1 1 TENA/THI-4/PQQC family Fructosamin_kin PF03881.14 KKK19615.1 - 0.0067 15.7 0.0 0.01 15.1 0.0 1.2 1 0 0 1 1 1 1 Fructosamine kinase ING PF12998.7 KKK19617.1 - 5.2e-07 30.2 0.0 9.6e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 KKK19617.1 - 1.7e-05 24.6 9.9 3.3e-05 23.7 9.9 1.5 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 KKK19617.1 - 0.051 13.8 1.2 0.11 12.7 1.2 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain GFO_IDH_MocA PF01408.22 KKK19618.1 - 1.4e-08 35.6 0.3 6.4e-08 33.5 0.3 2.1 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold DHDPS PF00701.22 KKK19619.1 - 1.2e-30 106.2 0.0 1.2e-22 79.9 0.0 2.0 2 0 0 2 2 2 2 Dihydrodipicolinate synthetase family PEP_mutase PF13714.6 KKK19619.1 - 0.027 13.9 0.0 0.046 13.2 0.0 1.3 1 0 0 1 1 1 0 Phosphoenolpyruvate phosphomutase ADH_N PF08240.12 KKK19620.1 - 3.4e-25 88.0 4.0 6.3e-25 87.2 4.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KKK19620.1 - 1.3e-17 64.0 0.1 3e-17 62.8 0.1 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 KKK19620.1 - 0.00019 20.8 0.1 0.00034 20.0 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ComGG PF14173.6 KKK19620.1 - 0.18 12.2 0.0 9.5 6.7 0.0 2.2 1 1 1 2 2 2 0 ComG operon protein 7 WD40 PF00400.32 KKK19621.1 - 1e-27 95.8 10.7 2.3e-05 25.0 0.2 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat F-box-like PF12937.7 KKK19621.1 - 3.6e-12 46.0 0.1 7.6e-12 44.9 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KKK19621.1 - 2e-05 24.3 0.1 5.5e-05 22.9 0.1 1.8 1 0 0 1 1 1 1 F-box domain ANAPC4_WD40 PF12894.7 KKK19621.1 - 0.00078 19.7 0.0 5.2 7.5 0.0 4.1 1 1 4 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Elongin_A PF06881.11 KKK19621.1 - 0.0051 17.3 0.0 0.01 16.4 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A PQQ_2 PF13360.6 KKK19621.1 - 0.01 15.4 0.1 5.5 6.5 0.0 2.4 1 1 0 2 2 2 0 PQQ-like domain F-box_4 PF15966.5 KKK19621.1 - 0.011 15.6 0.0 0.022 14.6 0.0 1.5 1 0 0 1 1 1 0 F-box PQQ PF01011.21 KKK19621.1 - 0.011 15.6 0.2 26 5.0 0.1 3.7 3 0 0 3 3 3 0 PQQ enzyme repeat WD40_like PF17005.5 KKK19621.1 - 0.11 11.9 0.0 0.75 9.1 0.0 2.1 2 0 0 2 2 2 0 WD40-like domain zf-H2C2_2 PF13465.6 KKK19622.1 - 2e-05 24.8 6.4 2.9e-05 24.3 3.3 2.5 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2 PF00096.26 KKK19622.1 - 2.9e-05 24.3 19.5 3.6e-05 24.0 2.8 3.4 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KKK19622.1 - 0.00012 22.6 1.7 0.00012 22.6 1.7 3.2 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KKK19622.1 - 0.0016 18.6 0.7 0.0041 17.4 0.7 1.7 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KKK19622.1 - 0.0039 17.1 1.3 0.0089 16.0 1.3 1.6 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_8 PF15909.5 KKK19622.1 - 0.035 14.4 4.4 0.077 13.3 4.4 1.6 1 0 0 1 1 1 0 C2H2-type zinc ribbon FOXP-CC PF16159.5 KKK19622.1 - 0.17 12.6 10.9 0.31 11.7 1.7 3.7 2 1 2 4 4 4 0 FOXP coiled-coil domain zf-TRAF PF02176.18 KKK19622.1 - 0.73 10.6 8.4 0.21 12.3 2.4 2.3 2 0 0 2 2 2 0 TRAF-type zinc finger 2OG-FeII_Oxy_3 PF13640.6 KKK19623.1 - 1e-13 52.0 0.1 3.5e-13 50.2 0.1 1.8 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Fungal_trans PF04082.18 KKK19624.1 - 0.0031 16.6 0.1 0.0045 16.1 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain WYL_2 PF10902.8 KKK19624.1 - 0.0059 17.0 0.2 0.019 15.4 0.0 1.9 2 0 0 2 2 2 1 WYL_2, Sm-like SH3 beta-barrel fold CAP59_mtransfer PF11735.8 KKK19648.1 - 7.1e-74 248.5 0.0 9.2e-74 248.1 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 Gly_transf_sug PF04488.15 KKK19649.1 - 6.2e-08 33.2 0.0 1.2e-07 32.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Abhydrolase_6 PF12697.7 KKK19650.1 - 2.6e-06 28.2 2.9 5.1e-06 27.3 2.9 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KKK19650.1 - 1.6e-05 24.7 0.1 3e-05 23.8 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KKK19650.1 - 0.0084 15.0 0.0 0.011 14.6 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase NACHT PF05729.12 KKK19651.1 - 1.2e-06 28.6 0.0 6e-05 23.0 0.0 2.8 1 1 0 1 1 1 1 NACHT domain Abhydrolase_6 PF12697.7 KKK19651.1 - 1.6e-05 25.6 0.1 0.00026 21.7 0.0 2.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family AAA_22 PF13401.6 KKK19651.1 - 0.00045 20.5 0.0 0.0041 17.4 0.0 2.4 1 1 0 1 1 1 1 AAA domain DUF676 PF05057.14 KKK19651.1 - 0.0012 18.3 0.0 0.003 17.1 0.0 1.6 1 0 0 1 1 1 1 Putative serine esterase (DUF676) RNA_helicase PF00910.22 KKK19651.1 - 0.0051 17.2 0.0 0.012 16.0 0.0 1.6 1 0 0 1 1 1 1 RNA helicase Parvo_NS1 PF01057.17 KKK19651.1 - 0.03 13.4 0.0 0.1 11.7 0.0 1.7 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 PGAP1 PF07819.13 KKK19651.1 - 0.033 13.9 0.0 0.084 12.6 0.0 1.6 1 0 0 1 1 1 0 PGAP1-like protein AAA_16 PF13191.6 KKK19651.1 - 0.069 13.5 0.0 0.22 11.9 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain Abhydrolase_2 PF02230.16 KKK19651.1 - 0.07 12.9 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase AAA_16 PF13191.6 KKK19652.1 - 3.5e-07 30.8 0.1 1.5e-06 28.7 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain ATPase_2 PF01637.18 KKK19652.1 - 0.00076 19.5 0.0 0.0012 18.8 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_22 PF13401.6 KKK19652.1 - 0.0014 18.9 0.0 0.0045 17.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 KKK19652.1 - 0.016 15.7 0.0 0.045 14.2 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.13 KKK19652.1 - 0.016 14.4 0.0 0.028 13.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Glyco_hydro_130 PF04041.13 KKK19653.1 - 6e-36 124.0 0.0 7.7e-36 123.6 0.0 1.1 1 0 0 1 1 1 1 beta-1,4-mannooligosaccharide phosphorylase Glyco_hydro_43 PF04616.14 KKK19653.1 - 6.4e-09 35.5 2.0 0.0003 20.2 0.0 3.8 4 1 0 4 4 4 3 Glycosyl hydrolases family 43 Glyco_hydro_32N PF00251.20 KKK19653.1 - 9.4e-06 25.4 3.5 3.2e-05 23.7 0.0 2.4 3 0 0 3 3 3 1 Glycosyl hydrolases family 32 N-terminal domain MFS_1 PF07690.16 KKK19654.1 - 1.4e-43 149.2 47.2 5.9e-43 147.1 47.1 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KKK19654.1 - 1.8e-11 43.2 26.6 1.5e-09 36.9 26.6 2.8 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 KKK19654.1 - 0.0037 15.6 1.9 0.0037 15.6 1.9 2.2 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family Per1 PF04080.13 KKK19654.1 - 0.35 10.6 4.1 1.8 8.2 0.0 2.3 2 0 0 2 2 2 0 Per1-like family Xan_ur_permease PF00860.20 KKK19656.1 - 1.6e-67 227.9 35.2 2.6e-67 227.2 35.2 1.3 1 0 0 1 1 1 1 Permease family Pkinase_fungal PF17667.1 KKK19657.1 - 1.7e-09 36.9 0.0 2.2e-09 36.6 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase CS PF04969.16 KKK19658.1 - 3.1e-06 28.1 0.0 5e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 CS domain Snf7 PF03357.21 KKK19659.1 - 5.7e-20 71.6 15.1 5.7e-20 71.6 15.1 1.8 1 1 1 2 2 2 1 Snf7 DUF2408 PF10303.9 KKK19659.1 - 0.00048 20.7 5.5 0.00048 20.7 5.5 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2408) Gon7 PF08738.10 KKK19659.1 - 0.012 15.7 3.7 0.049 13.7 1.1 2.4 2 0 0 2 2 2 0 Gon7 family TPR_MLP1_2 PF07926.12 KKK19659.1 - 0.76 9.8 18.0 0.053 13.6 5.1 2.6 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein RRM_1 PF00076.22 KKK19660.1 - 6.7e-15 54.7 0.0 1.1e-14 54.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KKK19660.1 - 1.2e-05 25.0 0.0 2.3e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Occluded RNA-recognition motif FoP_duplication PF13865.6 KKK19660.1 - 2.5e-05 24.7 3.6 2.5e-05 24.7 3.6 2.9 3 0 0 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 RRM_7 PF16367.5 KKK19660.1 - 0.064 13.4 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif WSC PF01822.19 KKK19662.1 - 1.6e-13 50.7 7.1 1.6e-13 50.7 7.1 2.2 2 1 0 2 2 2 1 WSC domain DFRP_C PF16543.5 KKK19663.1 - 4.1e-25 88.1 10.0 4.1e-25 88.1 10.0 4.2 3 2 1 4 4 4 1 DRG Family Regulatory Proteins, Tma46 zf-CCCH_4 PF18044.1 KKK19663.1 - 1.6e-05 24.5 7.8 0.0002 21.1 1.6 3.3 3 0 0 3 3 3 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 KKK19663.1 - 2.9e-05 23.9 6.1 2.9e-05 23.9 6.1 3.1 3 0 0 3 3 3 1 Zinc finger domain Torus PF16131.5 KKK19663.1 - 4.3e-05 24.2 5.4 4.3e-05 24.2 5.4 3.8 2 2 1 3 3 3 2 Torus domain zf-CCCH PF00642.24 KKK19663.1 - 5e-05 23.1 0.9 5e-05 23.1 0.9 2.6 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_3 PF15663.5 KKK19663.1 - 0.0034 17.6 0.4 0.29 11.3 0.1 2.7 2 0 0 2 2 2 1 Zinc-finger containing family zf-CCCH_2 PF14608.6 KKK19663.1 - 0.013 16.0 13.4 0.032 14.7 3.7 2.9 2 1 0 2 2 2 0 RNA-binding, Nab2-type zinc finger Sugar_tr PF00083.24 KKK19664.1 - 3e-105 352.7 20.1 3.5e-105 352.5 20.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKK19664.1 - 6.8e-19 68.0 35.7 2.9e-17 62.7 22.3 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Phage_holin_2_3 PF16080.5 KKK19664.1 - 1.6 8.5 5.8 1.3 8.8 0.3 3.2 3 0 0 3 3 3 0 Bacteriophage holin family HP1 DAO PF01266.24 KKK19665.1 - 1.3e-30 107.2 0.1 1.5e-30 107.0 0.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Fcf1 PF04900.12 KKK19666.1 - 1.3e-33 115.3 1.4 5.2e-33 113.4 0.1 1.9 2 0 0 2 2 2 1 Fcf1 PIN_9 PF18477.1 KKK19666.1 - 4.3e-09 36.7 0.2 1e-08 35.5 0.0 1.6 2 0 0 2 2 2 1 PIN like domain Y_phosphatase3 PF13350.6 KKK19669.1 - 2.1e-53 181.7 0.0 2.4e-53 181.5 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 KKK19669.1 - 0.0025 17.4 0.0 0.0039 16.8 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 KKK19669.1 - 0.0082 15.7 0.0 0.012 15.2 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Myotub-related PF06602.14 KKK19669.1 - 0.077 11.9 0.0 0.11 11.4 0.0 1.1 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain PTPlike_phytase PF14566.6 KKK19669.1 - 0.12 12.5 0.0 0.23 11.6 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate MFS_1 PF07690.16 KKK19670.1 - 2.8e-16 59.4 29.7 2.8e-16 59.4 29.7 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily PIG-L PF02585.17 KKK19671.1 - 5.8e-19 69.0 0.2 8.4e-19 68.5 0.2 1.2 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase PBP PF01161.20 KKK19672.1 - 3.7e-15 56.4 0.2 4.7e-15 56.1 0.2 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein zf-CHY PF05495.12 KKK19694.1 - 0.087 13.3 2.1 0.12 12.9 2.1 1.2 1 0 0 1 1 1 0 CHY zinc finger zf-Paramyx-P PF13008.7 KKK19694.1 - 0.55 9.7 6.7 0.52 9.8 0.3 2.5 1 1 0 2 2 2 0 Zinc-binding domain of Paramyxoviridae V protein UBA_4 PF14555.6 KKK19695.1 - 6.6e-12 45.1 0.1 1.3e-11 44.1 0.1 1.6 1 0 0 1 1 1 1 UBA-like domain UIM PF02809.20 KKK19695.1 - 0.082 12.9 1.0 0.33 11.0 1.0 2.1 1 0 0 1 1 1 0 Ubiquitin interaction motif Pkinase PF00069.25 KKK19696.1 - 7.5e-73 245.1 0.0 9.8e-73 244.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK19696.1 - 3.6e-36 124.8 0.0 5e-36 124.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase AdenylateSensor PF16579.5 KKK19696.1 - 8.1e-18 65.0 0.0 4.8e-12 46.4 0.0 2.5 2 0 0 2 2 2 2 Adenylate sensor of SNF1-like protein kinase UBA_2 PF08587.11 KKK19696.1 - 4.3e-13 49.1 0.0 9.6e-13 48.0 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin associated domain (UBA) Kinase-like PF14531.6 KKK19696.1 - 4e-06 26.3 0.0 6.6e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 KKK19696.1 - 0.00012 21.7 0.1 0.00023 20.8 0.1 1.3 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 KKK19696.1 - 0.0089 15.0 0.1 0.015 14.3 0.1 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KKK19696.1 - 0.034 13.5 0.1 0.086 12.2 0.1 1.7 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KKK19696.1 - 0.079 12.9 0.1 0.079 12.9 0.1 2.7 2 1 1 3 3 3 0 Phosphotransferase enzyme family YukC PF10140.9 KKK19696.1 - 0.084 11.7 0.1 0.12 11.2 0.1 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC ABC_tran PF00005.27 KKK19706.1 - 1.9e-35 122.4 0.0 2.2e-16 60.6 0.0 2.5 2 0 0 2 2 2 2 ABC transporter RLI PF04068.15 KKK19706.1 - 9.8e-14 50.9 4.9 9.8e-14 50.9 4.9 1.9 2 0 0 2 2 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI AAA_21 PF13304.6 KKK19706.1 - 2.6e-10 40.6 5.6 0.12 12.2 0.0 4.5 2 2 2 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KKK19706.1 - 3.8e-10 39.6 2.1 0.0087 15.5 0.0 4.1 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 KKK19706.1 - 2.3e-05 24.3 0.2 0.29 10.8 0.0 3.1 3 0 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 KKK19706.1 - 2.9e-05 24.4 0.0 0.0057 16.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 KKK19706.1 - 4.1e-05 24.0 0.0 0.042 14.3 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Fer4 PF00037.27 KKK19706.1 - 9e-05 22.1 2.5 9e-05 22.1 2.5 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain Rad17 PF03215.15 KKK19706.1 - 9.8e-05 22.3 0.1 0.026 14.4 0.0 2.5 2 1 0 2 2 2 1 Rad17 P-loop domain AAA_16 PF13191.6 KKK19706.1 - 0.00015 22.2 0.0 0.26 11.7 0.0 2.5 2 1 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 KKK19706.1 - 0.00029 20.8 0.0 0.67 9.8 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_18 PF13238.6 KKK19706.1 - 0.00042 20.9 0.0 0.94 10.0 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KKK19706.1 - 0.0011 18.7 0.3 0.75 9.6 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_24 PF13479.6 KKK19706.1 - 0.0012 18.6 1.5 0.1 12.3 0.1 2.5 2 0 0 2 2 2 1 AAA domain AAA_13 PF13166.6 KKK19706.1 - 0.002 16.9 0.0 0.0045 15.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 KKK19706.1 - 0.0035 17.7 0.4 1.2 9.5 0.0 2.8 3 0 0 3 3 2 1 RNA helicase Fer4_21 PF14697.6 KKK19706.1 - 0.0038 17.3 11.0 0.0089 16.1 11.0 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain AAA_7 PF12775.7 KKK19706.1 - 0.005 16.4 0.5 0.064 12.8 0.1 2.2 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_33 PF13671.6 KKK19706.1 - 0.0077 16.4 0.0 1.3 9.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 KKK19706.1 - 0.0081 16.7 1.6 1.1 9.7 0.5 2.9 3 0 0 3 3 3 1 AAA domain SRP54 PF00448.22 KKK19706.1 - 0.0089 15.7 2.7 0.2 11.3 0.1 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Fer4_6 PF12837.7 KKK19706.1 - 0.0097 16.0 2.2 0.0097 16.0 2.2 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain NB-ARC PF00931.22 KKK19706.1 - 0.016 14.4 0.0 1.4 8.1 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain DLIC PF05783.11 KKK19706.1 - 0.017 13.9 0.0 0.031 13.1 0.0 1.3 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) AAA_28 PF13521.6 KKK19706.1 - 0.018 15.3 0.0 3.5 7.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 KKK19706.1 - 0.019 14.9 0.1 0.23 11.5 0.0 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Fer4_10 PF13237.6 KKK19706.1 - 0.023 14.8 1.3 0.023 14.8 1.3 2.6 1 1 1 2 2 2 0 4Fe-4S dicluster domain NACHT PF05729.12 KKK19706.1 - 0.045 13.7 2.2 1.7 8.5 0.0 2.4 2 0 0 2 2 2 0 NACHT domain Fer4_9 PF13187.6 KKK19706.1 - 0.082 13.1 11.7 0.19 11.9 11.7 1.7 1 0 0 1 1 1 0 4Fe-4S dicluster domain AAA_14 PF13173.6 KKK19706.1 - 0.092 12.8 0.1 4.5 7.3 0.0 2.7 2 1 0 2 2 2 0 AAA domain Fer4_16 PF13484.6 KKK19706.1 - 0.094 13.7 0.2 0.094 13.7 0.2 2.9 2 0 0 2 2 2 0 4Fe-4S double cluster binding domain VirE PF05272.11 KKK19706.1 - 0.11 12.2 0.0 8 6.1 0.0 2.4 2 0 0 2 2 2 0 Virulence-associated protein E AAA_30 PF13604.6 KKK19706.1 - 0.12 12.1 1.1 6.3 6.5 0.0 2.6 2 1 0 2 2 2 0 AAA domain Thymidylate_kin PF02223.17 KKK19706.1 - 0.14 11.8 0.6 18 5.0 0.0 2.7 3 0 0 3 3 2 0 Thymidylate kinase ATPase PF06745.13 KKK19706.1 - 0.15 11.4 0.1 0.3 10.4 0.1 1.5 1 0 0 1 1 1 0 KaiC PduV-EutP PF10662.9 KKK19706.1 - 0.18 11.6 2.1 0.21 11.3 0.1 2.1 2 0 0 2 2 1 0 Ethanolamine utilisation - propanediol utilisation Fer4_8 PF13183.6 KKK19706.1 - 0.27 11.7 6.4 0.39 11.2 0.2 2.7 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_7 PF12838.7 KKK19706.1 - 0.73 10.5 12.6 0.094 13.3 1.6 2.4 1 1 2 3 3 3 0 4Fe-4S dicluster domain Fer4_2 PF12797.7 KKK19706.1 - 7 7.0 9.6 0.31 11.2 1.2 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain SNF2_N PF00176.23 KKK19707.1 - 2.8e-59 200.6 0.0 4.3e-59 200.0 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Chromo PF00385.24 KKK19707.1 - 4.3e-27 93.8 1.9 1.8e-17 63.0 0.6 3.0 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain DUF4208 PF13907.6 KKK19707.1 - 6.3e-23 81.0 0.9 2.5e-22 79.1 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4208) Helicase_C PF00271.31 KKK19707.1 - 1.4e-18 67.2 0.0 5.2e-18 65.4 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Cdh1_DBD_1 PF18196.1 KKK19707.1 - 3.7e-07 30.5 12.3 5.8e-05 23.4 0.7 4.0 2 1 1 3 3 3 2 Chromodomain helicase DNA-binding domain 1 ResIII PF04851.15 KKK19707.1 - 9.1e-07 29.0 0.0 2.4e-05 24.4 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 KKK19707.1 - 3.9e-05 23.0 0.0 0.00017 20.9 0.0 2.0 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 CHDCT2 PF08074.11 KKK19707.1 - 0.022 14.9 0.1 0.11 12.6 0.0 2.3 2 0 0 2 2 2 0 CHDCT2 (NUC038) domain SLIDE PF09111.10 KKK19707.1 - 0.069 13.2 0.1 2.5 8.2 0.0 3.4 3 0 0 3 3 3 0 SLIDE CDH1_2_SANT_HL1 PF18375.1 KKK19707.1 - 1.8 9.3 8.9 1.3 9.7 1.3 3.4 2 0 0 2 2 2 0 CDH1/2 SANT-Helical linker 1 Hist_deacetyl PF00850.19 KKK19713.1 - 2.7e-51 174.9 0.0 4.5e-51 174.2 0.0 1.3 1 0 0 1 1 1 1 Histone deacetylase domain RTP801_C PF07809.11 KKK19713.1 - 0.024 14.6 0.0 0.053 13.4 0.0 1.5 1 0 0 1 1 1 0 RTP801 C-terminal region INSC_LBD PF16748.5 KKK19713.1 - 0.11 12.0 0.1 0.21 11.1 0.1 1.4 1 0 0 1 1 1 0 Inscuteable LGN-binding domain zf-AN1 PF01428.16 KKK19714.1 - 9.9e-23 80.0 22.3 5.7e-12 45.6 8.4 2.2 2 0 0 2 2 2 2 AN1-like Zinc finger Transp_Tc5_C PF04236.15 KKK19714.1 - 0.01 16.2 12.6 0.049 14.0 4.0 2.4 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain C1_4 PF07975.12 KKK19714.1 - 0.032 14.4 14.4 0.52 10.6 4.3 3.0 2 1 0 2 2 2 0 TFIIH C1-like domain zf-RING_5 PF14634.6 KKK19714.1 - 0.046 13.7 0.8 0.046 13.7 0.8 2.5 2 0 0 2 2 2 0 zinc-RING finger domain IBR PF01485.21 KKK19714.1 - 0.49 10.6 19.9 0.27 11.5 4.1 2.7 2 1 0 2 2 2 0 IBR domain, a half RING-finger domain zinc_ribbon_5 PF13719.6 KKK19714.1 - 9.6 6.1 8.5 1.1 9.1 1.3 2.5 2 0 0 2 2 2 0 zinc-ribbon domain Ala_racemase_N PF01168.20 KKK19715.1 - 5.1e-20 72.1 0.2 6.8e-20 71.7 0.2 1.2 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain FeThRed_B PF02943.15 KKK19716.1 - 0.048 13.7 3.3 0.065 13.2 3.3 1.2 1 0 0 1 1 1 0 Ferredoxin thioredoxin reductase catalytic beta chain MFS_1 PF07690.16 KKK19717.1 - 1.1e-27 97.0 27.5 1.5e-27 96.5 27.5 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily RAG1 PF12940.7 KKK19718.1 - 0.025 12.7 0.0 0.031 12.4 0.0 1.1 1 0 0 1 1 1 0 Recombination-activation protein 1 (RAG1), recombinase DND1_DSRM PF14709.7 KKK19718.1 - 0.11 12.8 0.0 12 6.2 0.0 2.3 2 0 0 2 2 2 0 double strand RNA binding domain from DEAD END PROTEIN 1 Thymidylat_synt PF00303.19 KKK19719.1 - 1.9e-89 299.3 0.0 2.2e-89 299.1 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase TGT PF01702.18 KKK19720.1 - 8.1e-144 479.1 0.0 9.7e-144 478.8 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase PsbJ PF01788.17 KKK19720.1 - 0.043 13.7 0.1 0.096 12.6 0.1 1.5 1 0 0 1 1 1 0 PsbJ Adaptin_N PF01602.20 KKK19721.1 - 3.7e-85 286.5 4.5 4.5e-85 286.2 4.5 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.16 KKK19721.1 - 4.8e-45 152.4 0.0 1.2e-44 151.1 0.0 1.7 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.20 KKK19721.1 - 4.9e-17 62.2 0.0 1.2e-16 61.0 0.0 1.7 1 0 0 1 1 1 1 Adaptin C-terminal domain Cnd1 PF12717.7 KKK19721.1 - 0.0039 17.2 1.7 0.37 10.8 0.1 2.7 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 RIX1 PF08167.12 KKK19721.1 - 0.038 13.7 0.0 7.9 6.2 0.0 3.2 1 1 2 3 3 3 0 rRNA processing/ribosome biogenesis RTP1_C1 PF10363.9 KKK19721.1 - 0.098 12.8 0.2 1.3 9.3 0.1 2.8 3 0 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 CDC45 PF02724.14 KKK19722.1 - 0.21 9.8 3.1 0.24 9.7 3.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Peptidase_C15 PF01470.17 KKK19729.1 - 1.1e-11 45.4 0.0 0.0022 18.2 0.0 3.1 2 1 1 3 3 3 3 Pyroglutamyl peptidase MOSC PF03473.17 KKK19730.1 - 1.3e-30 106.1 0.1 2.1e-30 105.4 0.1 1.3 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 KKK19730.1 - 2.6e-20 72.5 0.0 1.4e-19 70.1 0.0 2.1 1 1 0 1 1 1 1 MOSC N-terminal beta barrel domain SR-25 PF10500.9 KKK19730.1 - 0.001 18.8 4.8 0.0019 17.9 4.8 1.4 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein IMUP PF15761.5 KKK19730.1 - 0.0083 16.8 0.7 0.019 15.7 0.7 1.6 1 0 0 1 1 1 1 Immortalisation up-regulated protein Mad3_BUB1_I PF08311.12 KKK19732.1 - 4.8e-44 149.3 0.0 1.1e-43 148.2 0.0 1.6 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Mad3_BUB1_II PF08171.11 KKK19732.1 - 5.6e-14 52.1 0.2 7.2e-13 48.5 0.0 2.7 3 0 0 3 3 3 1 Mad3/BUB1 homology region 2 Pkinase PF00069.25 KKK19732.1 - 3.1e-09 36.6 0.0 8.5e-09 35.2 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Mad3_BUB1_I_2 PF17014.5 KKK19732.1 - 0.0029 17.7 0.0 0.0069 16.5 0.0 1.6 1 0 0 1 1 1 1 Putative Mad3/BUB1 like region 1 protein Pkinase_Tyr PF07714.17 KKK19732.1 - 0.038 13.3 0.0 0.11 11.7 0.0 1.7 2 0 0 2 2 2 0 Protein tyrosine kinase Kinase-like PF14531.6 KKK19732.1 - 0.19 11.0 0.0 0.34 10.2 0.0 1.3 1 0 0 1 1 1 0 Kinase-like AP_endonuc_2 PF01261.24 KKK19733.1 - 6.8e-30 104.1 0.1 2.2e-29 102.4 0.0 1.7 2 0 0 2 2 2 1 Xylose isomerase-like TIM barrel TPT PF03151.16 KKK19734.1 - 6.6e-17 61.8 16.4 6.6e-17 61.8 16.4 1.7 2 0 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.20 KKK19734.1 - 3.6e-05 23.9 35.7 0.0047 17.1 16.6 2.6 2 1 0 2 2 2 2 EamA-like transporter family PUNUT PF16913.5 KKK19734.1 - 0.0011 18.2 16.9 0.0017 17.7 16.9 1.3 1 0 0 1 1 1 1 Purine nucleobase transmembrane transport REV PF00424.18 KKK19734.1 - 0.0052 16.8 0.4 0.0098 15.9 0.4 1.4 1 0 0 1 1 1 1 REV protein (anti-repression trans-activator protein) PBP1_TM PF14812.6 KKK19734.1 - 2.5 8.5 17.1 7.8 7.0 3.0 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Cwf_Cwc_15 PF04889.12 KKK19734.1 - 3.7 7.2 18.2 1.8 8.2 7.0 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein ADH_zinc_N PF00107.26 KKK19760.1 - 5.4e-10 39.4 0.0 9.4e-10 38.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KKK19760.1 - 9.2e-07 28.7 0.0 6.1e-06 26.1 0.0 2.0 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KKK19760.1 - 0.0018 19.3 0.0 0.0032 18.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 KKK19760.1 - 0.0075 16.2 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase DUF1768 PF08719.11 KKK19761.1 - 2.8e-28 99.2 0.0 4.2e-28 98.6 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) Med1 PF10744.9 KKK19777.1 - 4.6e-126 421.2 0.0 5.7e-126 420.9 0.0 1.1 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription subunit 1 WD40 PF00400.32 KKK19778.1 - 7.9e-47 156.3 22.8 7.9e-10 39.2 0.2 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKK19778.1 - 7.8e-09 35.7 0.4 0.06 13.6 0.0 4.5 3 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KKK19778.1 - 0.00029 19.6 4.6 0.63 8.6 0.1 4.6 1 1 5 6 6 6 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KKK19778.1 - 0.0017 17.4 0.1 2.5 7.0 0.0 3.8 2 2 2 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 KKK19778.1 - 0.014 14.0 0.1 1.5 7.3 0.0 2.2 2 0 0 2 2 2 0 Cytochrome D1 heme domain PD40 PF07676.12 KKK19778.1 - 0.02 14.8 0.1 22 5.1 0.0 4.1 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat WD40_like PF17005.5 KKK19778.1 - 0.03 13.6 0.0 5.3 6.3 0.0 2.8 2 1 0 3 3 3 0 WD40-like domain TPR_2 PF07719.17 KKK19779.1 - 1e-05 25.2 5.2 0.0013 18.7 0.1 4.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 KKK19779.1 - 1.1e-05 25.7 0.7 0.027 14.8 0.0 4.5 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 KKK19779.1 - 0.00015 21.4 8.3 0.0014 18.4 0.1 3.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_10 PF13374.6 KKK19779.1 - 0.013 15.3 0.0 0.013 15.3 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 KKK19779.1 - 0.25 11.5 2.5 1.1 9.4 0.0 3.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 KKK19779.1 - 0.31 11.4 0.1 0.31 11.4 0.1 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat SRAP PF02586.14 KKK19780.1 - 2.4e-79 265.9 0.0 3.7e-79 265.3 0.0 1.3 1 0 0 1 1 1 1 SOS response associated peptidase (SRAP) Sdh5 PF03937.16 KKK19782.1 - 1.9e-24 85.4 1.1 4.6e-24 84.2 0.5 2.0 3 0 0 3 3 3 1 Flavinator of succinate dehydrogenase Pkinase PF00069.25 KKK19793.1 - 3.9e-24 85.4 0.0 1e-23 84.0 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK19793.1 - 3.2e-09 36.4 0.0 0.002 17.5 0.0 2.0 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 KKK19793.1 - 0.0042 15.9 0.2 0.098 11.4 0.1 2.0 1 1 0 2 2 2 1 Fungal protein kinase SRF-TF PF00319.18 KKK19794.1 - 9.7e-24 82.6 0.2 1.5e-23 82.0 0.2 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) CIAPIN1 PF05093.13 KKK19795.1 - 9.8e-42 141.5 2.6 1.7e-41 140.7 2.6 1.4 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis DRE2_N PF16803.5 KKK19795.1 - 4.2e-37 127.3 0.0 5.8e-37 126.9 0.0 1.2 1 0 0 1 1 1 1 Fe-S cluster assembly protein DRE2 N-terminus Dicty_REP PF05086.12 KKK19796.1 - 3.2 5.6 13.5 4.7 5.1 13.5 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein MGC-24 PF05283.11 KKK19796.1 - 3.4 8.1 29.8 7.8 6.9 29.8 1.7 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin RIFIN PF02009.16 KKK19796.1 - 9.5 6.0 12.0 15 5.4 12.0 1.3 1 0 0 1 1 1 0 Rifin Peptidase_M28 PF04389.17 KKK19797.1 - 1.7e-40 138.8 0.1 3.3e-40 137.9 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 KKK19797.1 - 5.5e-12 45.5 1.0 1.2e-11 44.4 1.0 1.6 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 KKK19797.1 - 0.00015 21.6 0.0 0.0011 18.7 0.0 2.4 2 1 0 2 2 2 1 Peptidase family M20/M25/M40 Nicastrin PF05450.15 KKK19797.1 - 0.085 12.3 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 Nicastrin Peptidase_M42 PF05343.14 KKK19797.1 - 0.16 11.0 0.0 0.9 8.5 0.0 2.1 2 0 0 2 2 2 0 M42 glutamyl aminopeptidase Exo_endo_phos PF03372.23 KKK19798.1 - 8.9e-11 41.7 0.0 6e-10 39.0 0.0 1.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LysM PF01476.20 KKK19799.1 - 8.6e-23 80.1 0.0 1.4e-06 28.3 0.0 4.2 4 0 0 4 4 4 4 LysM domain GMC_oxred_C PF05199.13 KKK19800.1 - 1.1e-33 116.8 1.3 2.3e-32 112.5 0.4 2.2 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_N PF00732.19 KKK19800.1 - 1.3e-30 106.9 0.0 3.6e-27 95.5 0.0 3.0 1 1 0 2 2 2 2 GMC oxidoreductase FAD_binding_2 PF00890.24 KKK19800.1 - 0.0011 18.2 0.2 0.0099 15.0 0.5 2.0 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 KKK19800.1 - 0.0015 17.9 0.0 0.0022 17.3 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KKK19800.1 - 0.0021 18.2 0.3 0.0078 16.4 0.1 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NepR PF18557.1 KKK19800.1 - 0.065 12.9 0.1 0.63 9.7 0.0 2.2 2 0 0 2 2 2 0 Anti-sigma factor NepR HI0933_like PF03486.14 KKK19800.1 - 0.19 10.4 0.2 2.3 6.8 0.1 2.0 2 0 0 2 2 2 0 HI0933-like protein ApbA PF02558.16 KKK19800.1 - 0.2 11.3 0.5 0.4 10.3 0.5 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA CHORD PF04968.12 KKK19801.1 - 0.6 10.9 0.0 0.6 10.9 0.0 2.8 4 0 0 4 4 4 0 CHORD Cas_CXXC_CXXC PF09706.10 KKK19801.1 - 2.2 8.6 5.7 27 5.1 0.0 3.6 4 0 0 4 4 4 0 CRISPR-associated protein (Cas_CXXC_CXXC) OSTMP1 PF09777.9 KKK19801.1 - 3.8 6.9 5.7 19 4.6 0.0 3.5 3 1 0 3 3 3 0 Osteopetrosis-associated transmembrane protein 1 precursor ZZ PF00569.17 KKK19801.1 - 3.9 7.4 10.3 4 7.3 0.1 4.2 5 0 0 5 5 5 0 Zinc finger, ZZ type F-box-like PF12937.7 KKK19802.1 - 0.0046 16.8 0.0 0.0091 15.9 0.0 1.5 1 0 0 1 1 1 1 F-box-like Fungal_trans PF04082.18 KKK19803.1 - 9.1e-13 47.8 1.1 2.6e-12 46.4 1.1 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK19803.1 - 8.9e-07 28.9 14.7 1.7e-06 28.1 14.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cu_amine_oxid PF01179.20 KKK19804.1 - 6e-157 522.8 0.1 7.9e-157 522.4 0.1 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 KKK19804.1 - 0.00064 20.1 0.0 0.0014 19.0 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.16 KKK19804.1 - 0.014 15.7 0.0 0.027 14.7 0.0 1.5 1 0 0 1 1 1 0 Copper amine oxidase, N2 domain CorA PF01544.18 KKK19805.1 - 0.0003 20.2 0.1 0.0003 20.2 0.1 2.0 2 1 0 2 2 2 1 CorA-like Mg2+ transporter protein FAA_hydro_N_2 PF18288.1 KKK19805.1 - 0.028 14.9 0.0 0.14 12.6 0.0 2.2 2 0 0 2 2 2 0 Fumarylacetoacetase N-terminal domain 2 MerR-DNA-bind PF09278.11 KKK19805.1 - 1.3 9.6 7.2 0.81 10.3 1.6 2.6 2 0 0 2 2 2 0 MerR, DNA binding 2OG-FeII_Oxy PF03171.20 KKK19806.1 - 1.9e-13 50.7 0.0 3e-13 50.1 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Ribonuc_L-PSP PF01042.21 KKK19807.1 - 5.1e-17 62.0 0.0 8.1e-17 61.4 0.0 1.3 1 1 0 1 1 1 1 Endoribonuclease L-PSP CENP-B_dimeris PF09026.10 KKK19809.1 - 0.026 14.9 4.5 0.06 13.7 4.5 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain RVT_1 PF00078.27 KKK19809.1 - 0.056 13.0 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) NOA36 PF06524.12 KKK19809.1 - 0.15 11.4 4.1 0.27 10.5 4.1 1.3 1 0 0 1 1 1 0 NOA36 protein 3-HAO PF06052.12 KKK19810.1 - 3.4e-54 182.6 0.1 4.3e-54 182.3 0.1 1.1 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.11 KKK19810.1 - 0.0027 17.4 0.0 0.0046 16.6 0.0 1.4 1 0 0 1 1 1 1 Cupin domain fn3_4 PF16794.5 KKK19810.1 - 0.024 14.6 0.1 6 6.8 0.1 2.3 2 0 0 2 2 2 0 Fibronectin-III type domain Amidohydro_2 PF04909.14 KKK19811.1 - 8.9e-46 157.0 0.2 1e-45 156.8 0.2 1.0 1 0 0 1 1 1 1 Amidohydrolase Aldedh PF00171.22 KKK19812.1 - 7.4e-145 483.0 0.0 8.4e-145 482.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family UL2 PF08196.11 KKK19812.1 - 0.17 11.9 0.1 8.4 6.4 0.0 2.5 2 0 0 2 2 2 0 UL2 protein Adaptin_N PF01602.20 KKK19813.1 - 7.4e-142 473.6 3.2 8.7e-142 473.3 3.2 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 KKK19813.1 - 4.7e-19 68.7 0.0 9.4e-19 67.8 0.0 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain Cnd1 PF12717.7 KKK19813.1 - 1.1e-08 35.3 5.0 0.00022 21.3 0.1 4.3 2 1 2 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KKK19813.1 - 3.8e-06 27.2 3.1 0.08 13.3 0.0 3.9 4 0 0 4 4 4 2 HEAT repeats HEAT PF02985.22 KKK19813.1 - 0.0026 17.9 1.8 6.6 7.3 0.1 4.3 4 0 0 4 4 4 1 HEAT repeat HEAT_EZ PF13513.6 KKK19813.1 - 0.016 15.7 0.1 26 5.4 0.0 4.7 4 0 0 4 4 4 0 HEAT-like repeat RICTOR_M PF14666.6 KKK19813.1 - 0.02 14.7 0.4 0.088 12.6 0.1 2.3 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR, middle domain Cohesin_HEAT PF12765.7 KKK19813.1 - 0.19 12.1 0.7 0.56 10.6 0.2 2.2 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion DnaJ PF00226.31 KKK19814.1 - 1.3e-21 76.4 0.9 1.3e-21 76.4 0.9 2.0 2 0 0 2 2 2 1 DnaJ domain Pkinase PF00069.25 KKK19815.1 - 1.6e-09 37.5 0.0 3.7e-09 36.3 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK19815.1 - 4.5e-08 32.7 0.0 9.2e-08 31.7 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KKK19815.1 - 0.052 12.9 0.0 0.09 12.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KKK19815.1 - 0.063 13.2 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family F-box-like PF12937.7 KKK19816.1 - 1.5e-12 47.1 0.6 1.5e-12 47.1 0.6 2.3 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 KKK19816.1 - 2.1e-12 47.0 11.7 0.35 11.4 0.1 8.0 4 2 4 9 9 9 5 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KKK19816.1 - 3.2e-11 42.3 19.4 1.3 9.3 0.0 11.2 12 0 0 12 12 12 3 Leucine Rich repeat F-box PF00646.33 KKK19816.1 - 2.7e-05 23.9 0.2 2.7e-05 23.9 0.2 2.5 3 0 0 3 3 3 1 F-box domain DUF1699 PF08004.11 KKK19816.1 - 0.00031 20.4 1.1 0.055 13.1 0.0 3.9 3 2 0 4 4 4 1 Protein of unknown function (DUF1699) LRR_8 PF13855.6 KKK19816.1 - 0.076 12.8 9.3 2 8.3 0.0 5.7 7 2 0 7 7 7 0 Leucine rich repeat Preseq_ALAS PF09029.10 KKK19816.1 - 0.89 10.0 5.2 0.75 10.3 0.1 3.2 3 1 1 4 4 4 0 5-aminolevulinate synthase presequence AMP-binding PF00501.28 KKK19817.1 - 2.2e-73 247.3 0.0 3e-73 246.8 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KKK19817.1 - 4.8e-19 69.1 0.1 1.1e-18 68.0 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain MBOAT PF03062.19 KKK19818.1 - 1.2e-41 143.2 19.9 1.9e-41 142.6 15.4 2.1 2 0 0 2 2 2 2 MBOAT, membrane-bound O-acyltransferase family TonB_N PF16031.5 KKK19819.1 - 4.2 7.9 9.9 0.041 14.4 1.6 1.9 2 0 0 2 2 2 0 TonB polyproline region Zn_clus PF00172.18 KKK19819.1 - 6.3 7.0 12.2 0.81 9.9 7.6 1.9 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain TauD PF02668.16 KKK19820.1 - 4e-16 59.6 0.3 7.1e-09 35.8 0.2 2.2 1 1 1 2 2 2 2 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 KKK19820.1 - 0.055 12.6 0.4 0.094 11.8 0.4 1.2 1 0 0 1 1 1 0 CsiD DUF3841 PF12952.7 KKK19820.1 - 0.13 12.0 0.1 0.23 11.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3841) Peptidase_M28 PF04389.17 KKK19822.1 - 2.5e-35 122.0 0.0 4.6e-35 121.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 KKK19822.1 - 0.017 14.8 0.0 0.03 14.0 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 ATP-synt_8 PF00895.20 KKK19822.1 - 0.02 15.4 0.2 0.02 15.4 0.2 3.9 4 0 0 4 4 4 0 ATP synthase protein 8 Ribosomal_60s PF00428.19 KKK19822.1 - 0.25 11.9 4.6 0.56 10.8 4.6 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein PBP1_TM PF14812.6 KKK19822.1 - 1.5 9.2 8.9 14 6.2 7.8 2.6 1 1 1 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CENP-B_dimeris PF09026.10 KKK19822.1 - 2 8.8 10.1 5.3 7.5 10.1 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Pox_Ag35 PF03286.14 KKK19822.1 - 2.1 8.1 3.6 3.4 7.4 3.6 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DNA_pol_phi PF04931.13 KKK19822.1 - 5 5.1 9.5 6.9 4.6 9.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi DUF2457 PF10446.9 KKK19822.1 - 5.2 6.1 10.8 7.9 5.5 10.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Ribosomal_L13 PF00572.18 KKK19823.1 - 4.7e-12 46.2 0.0 4.3e-10 39.9 0.0 2.3 1 1 0 1 1 1 1 Ribosomal protein L13 Aminotran_1_2 PF00155.21 KKK19824.1 - 1.5e-61 208.6 0.0 1.8e-61 208.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 KKK19824.1 - 0.0017 17.7 0.0 0.0023 17.2 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 KKK19824.1 - 0.027 13.4 0.0 0.04 12.9 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 KKK19824.1 - 0.055 12.8 0.0 0.14 11.4 0.0 1.7 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family LisH PF08513.11 KKK19836.1 - 1.8e-05 24.5 0.2 3.6e-05 23.6 0.2 1.5 1 0 0 1 1 1 1 LisH TRAPP PF04051.16 KKK19837.1 - 5.1e-37 126.8 0.0 6.5e-37 126.5 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component DUF4250 PF14056.6 KKK19837.1 - 0.058 13.3 0.1 0.13 12.2 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4250) Terminase_4 PF05119.12 KKK19837.1 - 0.18 12.2 0.1 0.26 11.7 0.1 1.3 1 0 0 1 1 1 0 Phage terminase, small subunit WD40 PF00400.32 KKK19839.1 - 4.2e-44 147.7 3.4 4.2e-07 30.6 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKK19839.1 - 2.8e-10 40.4 0.1 0.11 12.8 0.0 5.2 2 1 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KKK19839.1 - 0.00022 20.6 0.0 0.74 9.1 0.0 3.7 2 1 2 4 4 4 1 WD40-like domain Nucleoporin_N PF08801.11 KKK19839.1 - 0.00088 18.1 1.6 1.1 7.9 0.1 3.4 1 1 2 3 3 3 2 Nup133 N terminal like Nup160 PF11715.8 KKK19839.1 - 0.012 14.3 0.2 8.6 4.9 0.0 3.6 2 1 2 4 4 4 0 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KKK19839.1 - 0.09 11.7 0.0 4 6.3 0.0 2.5 2 1 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_2 PF13360.6 KKK19839.1 - 0.12 11.9 1.5 12 5.4 0.0 3.1 1 1 1 3 3 3 0 PQQ-like domain Pribosyltran PF00156.27 KKK19840.1 - 1.6e-14 53.7 0.0 2.2e-14 53.3 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 KKK19840.1 - 0.0055 16.2 0.0 0.0078 15.7 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase AIG2_2 PF13772.6 KKK19841.1 - 2.9e-05 24.4 0.0 0.00079 19.8 0.0 2.2 2 0 0 2 2 2 1 AIG2-like family TGF_beta_GS PF08515.12 KKK19841.1 - 0.32 10.5 2.8 0.55 9.8 2.8 1.3 1 0 0 1 1 1 0 Transforming growth factor beta type I GS-motif Glyco_hydro_47 PF01532.20 KKK19842.1 - 1.8e-119 399.7 0.0 2.3e-119 399.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Ribonuc_L-PSP PF01042.21 KKK19843.1 - 4e-39 133.4 0.0 4.4e-39 133.2 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP GTP_EFTU PF00009.27 KKK19845.1 - 2.4e-65 219.7 0.1 5.6e-65 218.5 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 KKK19845.1 - 3.5e-33 114.0 0.0 1.1e-32 112.4 0.0 1.9 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 KKK19845.1 - 2e-21 75.8 0.0 5.2e-21 74.5 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KKK19845.1 - 1.2e-13 51.3 0.0 3.5e-13 49.7 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 PWI PF01480.17 KKK19845.1 - 3.5e-13 49.7 0.1 7.6e-13 48.6 0.1 1.6 1 0 0 1 1 1 1 PWI domain EFG_II PF14492.6 KKK19845.1 - 2.2e-11 43.7 0.0 7.2e-11 42.0 0.0 1.9 1 0 0 1 1 1 1 Elongation Factor G, domain II Nup35_RRM_2 PF14605.6 KKK19845.1 - 1e-06 28.6 0.0 0.00028 20.8 0.0 2.6 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_1 PF00076.22 KKK19845.1 - 1.4e-06 28.0 0.7 0.00016 21.4 0.0 3.9 4 0 0 4 4 4 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MMR_HSR1 PF01926.23 KKK19845.1 - 1.8e-05 24.8 0.0 5.1e-05 23.3 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase RRM_occluded PF16842.5 KKK19845.1 - 0.00031 20.6 0.0 0.00091 19.0 0.0 1.8 1 0 0 1 1 1 1 Occluded RNA-recognition motif zf-CCCH PF00642.24 KKK19845.1 - 0.0016 18.3 0.9 0.0029 17.5 0.9 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KKK19845.1 - 0.22 11.6 0.6 0.4 10.8 0.6 1.5 1 0 0 1 1 1 0 Zinc finger domain Borrelia_P83 PF05262.11 KKK19845.1 - 0.58 8.6 8.7 0.99 7.8 8.7 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein RRM_3 PF08777.11 KKK19845.1 - 1.9 8.6 7.7 1.6 8.8 0.0 3.3 3 0 0 3 3 3 0 RNA binding motif DUF4407 PF14362.6 KKK19845.1 - 8.2 5.7 9.8 14 5.0 9.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) RIBIOP_C PF04950.12 KKK19846.1 - 1.3e-96 323.5 0.0 1.3e-96 323.5 0.0 1.5 2 0 0 2 2 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 KKK19846.1 - 2.6e-28 97.9 0.0 6.6e-28 96.6 0.0 1.8 1 0 0 1 1 1 1 AARP2CN (NUC121) domain AAA_22 PF13401.6 KKK19846.1 - 1.5e-05 25.2 0.2 4.8e-05 23.7 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.6 KKK19846.1 - 7.7e-05 23.1 0.0 0.00021 21.7 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain GTP_EFTU PF00009.27 KKK19846.1 - 0.00015 21.4 0.0 0.016 14.7 0.0 2.5 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_33 PF13671.6 KKK19846.1 - 0.00027 21.1 1.5 0.00038 20.6 0.0 2.1 2 0 0 2 2 1 1 AAA domain AAA PF00004.29 KKK19846.1 - 0.00074 20.0 0.0 0.0017 18.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 KKK19846.1 - 0.0022 18.1 0.1 0.0068 16.5 0.1 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.27 KKK19846.1 - 0.0054 17.2 1.1 0.017 15.6 0.0 2.4 3 0 0 3 3 1 1 ABC transporter AAA_19 PF13245.6 KKK19846.1 - 0.0059 16.9 0.0 0.013 15.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 KKK19846.1 - 0.0076 15.5 0.0 0.015 14.5 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain NACHT PF05729.12 KKK19846.1 - 0.0097 15.8 0.0 0.019 14.9 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_5 PF07728.14 KKK19846.1 - 0.016 15.2 0.2 0.14 12.2 0.1 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 KKK19846.1 - 0.017 14.6 0.0 0.041 13.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 KKK19846.1 - 0.019 15.3 0.0 0.046 14.1 0.0 1.6 1 0 0 1 1 1 0 RNA helicase cobW PF02492.19 KKK19846.1 - 0.022 14.4 0.2 0.039 13.5 0.2 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 KKK19846.1 - 0.025 14.3 0.0 0.052 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 KKK19846.1 - 0.038 13.7 0.0 0.37 10.5 0.0 2.1 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation NTPase_1 PF03266.15 KKK19846.1 - 0.038 13.9 0.3 0.072 13.0 0.3 1.4 1 0 0 1 1 1 0 NTPase RsgA_GTPase PF03193.16 KKK19846.1 - 0.039 13.9 0.0 0.13 12.2 0.0 1.8 2 0 0 2 2 2 0 RsgA GTPase MobB PF03205.14 KKK19846.1 - 0.048 13.6 0.1 0.3 11.0 0.1 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.6 KKK19846.1 - 0.056 14.0 0.1 0.056 14.0 0.1 2.8 3 0 0 3 3 2 0 AAA domain AAA_14 PF13173.6 KKK19846.1 - 0.059 13.4 0.0 0.19 11.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain Septin PF00735.18 KKK19846.1 - 0.078 12.2 1.1 0.32 10.2 0.0 2.1 2 0 0 2 2 2 0 Septin KAP_NTPase PF07693.14 KKK19846.1 - 0.082 12.1 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 KAP family P-loop domain ATPase_2 PF01637.18 KKK19846.1 - 0.085 12.8 0.0 0.085 12.8 0.0 1.9 2 0 0 2 2 1 0 ATPase domain predominantly from Archaea Roc PF08477.13 KKK19846.1 - 0.12 12.6 0.0 0.27 11.5 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 KKK19846.1 - 0.18 11.6 0.0 0.34 10.7 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_11 PF13086.6 KKK19846.1 - 0.29 10.9 0.1 0.29 10.9 0.1 3.2 3 0 0 3 3 3 0 AAA domain BCDHK_Adom3 PF10436.9 KKK19847.1 - 2.7e-35 121.6 0.1 4.2e-34 117.7 0.1 2.1 1 1 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 KKK19847.1 - 3.9e-12 46.7 0.0 1.2e-11 45.0 0.0 1.9 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim_4 PF13662.6 KKK19847.1 - 0.0074 16.7 0.1 9.2 6.8 0.0 3.2 3 0 0 3 3 3 1 Toprim domain HATPase_c_3 PF13589.6 KKK19847.1 - 0.13 12.1 0.0 0.84 9.5 0.0 2.1 1 1 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 KKK19847.1 - 0.16 11.9 0.1 0.62 10.0 0.1 1.9 1 1 0 1 1 1 0 Histidine kinase-like ATPase domain Aminotran_1_2 PF00155.21 KKK19848.1 - 1.1e-23 84.1 0.0 1.3e-23 83.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 KKK19848.1 - 9.3e-05 21.4 0.0 0.00014 20.8 0.0 1.3 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase Beta_elim_lyase PF01212.21 KKK19848.1 - 0.083 12.2 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 KKK19848.1 - 0.14 11.5 0.0 1.7 7.9 0.0 2.0 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family Glyoxalase PF00903.25 KKK19849.1 - 2.1e-10 40.9 0.0 1.1e-09 38.5 0.0 2.1 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 KKK19849.1 - 0.00064 20.0 0.0 0.0011 19.2 0.0 1.5 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 KKK19849.1 - 0.1 13.4 0.0 0.71 10.7 0.0 2.3 2 1 0 2 2 2 0 Glyoxalase-like domain UQ_con PF00179.26 KKK19924.1 - 3.6e-50 169.2 0.0 4.4e-50 169.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KKK19924.1 - 3.4e-05 23.6 0.0 5.3e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 KKK19924.1 - 0.00025 21.3 0.1 0.00034 20.9 0.1 1.4 1 1 0 1 1 1 1 RWD domain UEV PF05743.13 KKK19924.1 - 0.0023 17.8 0.0 0.0034 17.2 0.0 1.4 1 0 0 1 1 1 1 UEV domain Med26_C PF15693.5 KKK19924.1 - 0.032 14.4 0.0 0.063 13.4 0.0 1.5 2 0 0 2 2 2 0 Mediator complex subunit 26 C-terminal F-box-like PF12937.7 KKK19925.1 - 1.2e-07 31.5 0.1 2.4e-07 30.5 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KKK19925.1 - 1.7e-06 27.7 0.1 4.1e-06 26.5 0.0 1.7 2 0 0 2 2 2 1 F-box domain Nucleos_tra2_C PF07662.13 KKK19926.1 - 1.5e-72 243.8 0.2 1.5e-72 243.8 0.2 2.7 3 0 0 3 3 3 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 KKK19926.1 - 8.8e-23 80.7 4.6 8.8e-23 80.7 4.6 2.5 2 0 0 2 2 2 1 Na+ dependent nucleoside transporter N-terminus Gate PF07670.14 KKK19926.1 - 0.0075 16.5 8.5 0.0075 16.5 8.5 3.5 4 1 1 5 5 5 1 Nucleoside recognition Pkinase PF00069.25 KKK19927.1 - 2.2e-58 197.7 0.0 3.1e-58 197.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK19927.1 - 3.5e-25 88.8 0.0 4.9e-25 88.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KKK19927.1 - 4.1e-07 29.6 0.0 5.9e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KKK19927.1 - 0.0042 16.5 0.0 0.011 15.1 0.0 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KKK19927.1 - 0.042 13.8 0.0 0.45 10.4 0.0 2.3 2 0 0 2 2 2 0 Phosphotransferase enzyme family ATG2_CAD PF13329.6 KKK19928.1 - 4.1e-45 153.3 0.8 1.6e-44 151.4 0.1 2.4 3 0 0 3 3 3 1 Autophagy-related protein 2 CAD motif ATG_C PF09333.11 KKK19928.1 - 3.5e-30 104.2 0.0 1.2e-29 102.5 0.0 2.0 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain VPS13_C PF16909.5 KKK19928.1 - 0.1 12.3 0.1 0.46 10.2 0.0 2.1 2 0 0 2 2 2 0 Vacuolar-sorting-associated 13 protein C-terminal A_deaminase PF00962.22 KKK19929.1 - 0.00017 21.0 0.0 0.0013 18.1 0.0 2.0 2 0 0 2 2 2 1 Adenosine/AMP deaminase Ribosomal_L31e PF01198.19 KKK19930.1 - 2.9e-41 139.6 0.5 3.8e-41 139.2 0.5 1.2 1 0 0 1 1 1 1 Ribosomal protein L31e CN_hydrolase PF00795.22 KKK19931.1 - 2e-61 207.6 0.0 2.3e-61 207.4 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Ish1 PF10281.9 KKK19935.1 - 8.5e-86 282.0 12.3 3.2e-12 46.6 0.1 7.4 7 0 0 7 7 7 7 Putative stress-responsive nuclear envelope protein SAP PF02037.27 KKK19935.1 - 1.2e-10 40.9 0.0 0.67 9.8 0.0 6.3 5 1 0 5 5 5 3 SAP domain HeH PF12949.7 KKK19935.1 - 2.2e-09 36.9 0.0 0.38 10.5 0.0 5.6 6 0 0 6 6 6 2 HeH/LEM domain ANAPC2 PF08672.11 KKK19935.1 - 9.4e-05 22.9 0.6 34 5.0 0.0 5.6 6 0 0 6 6 6 0 Anaphase promoting complex (APC) subunit 2 Slx4 PF09494.10 KKK19935.1 - 9.5e-05 22.3 3.5 20 5.3 0.0 5.8 7 0 0 7 7 7 0 Slx4 endonuclease LEM PF03020.15 KKK19935.1 - 0.027 14.0 0.0 18 5.0 0.0 4.0 5 0 0 5 5 5 0 LEM domain CPSase_sm_chain PF00988.22 KKK19935.1 - 0.081 12.7 0.0 9.3 6.1 0.0 3.7 5 0 0 5 5 5 0 Carbamoyl-phosphate synthase small chain, CPSase domain SAM_2 PF07647.17 KKK19935.1 - 0.22 11.7 9.3 15 5.8 0.0 5.9 6 1 1 7 7 7 0 SAM domain (Sterile alpha motif) TIR_2 PF13676.6 KKK19935.1 - 0.32 11.6 2.3 1.2 9.8 0.2 3.0 2 1 1 3 3 2 0 TIR domain DUF4230 PF14014.6 KKK19935.1 - 2.5 8.4 4.2 42 4.4 0.8 3.5 3 1 1 4 4 4 0 Protein of unknown function (DUF4230) Apolipoprotein PF01442.18 KKK19935.1 - 3.9 7.3 12.6 5.1 6.9 7.4 3.1 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain PQ-loop PF04193.14 KKK19936.1 - 6e-20 70.8 15.3 2.8e-11 43.0 5.2 3.5 3 1 1 4 4 4 2 PQ loop repeat LtrA PF06772.11 KKK19936.1 - 0.02 14.1 4.1 0.044 13.0 4.1 1.5 1 1 0 1 1 1 0 Bacterial low temperature requirement A protein (LtrA) CTV_P6 PF06706.11 KKK19936.1 - 0.18 11.5 2.9 0.9 9.3 0.5 2.6 2 0 0 2 2 2 0 Citrus tristeza virus 6-kDa protein YwiC PF14256.6 KKK19936.1 - 0.46 10.8 7.2 0.13 12.6 2.6 2.3 1 1 0 2 2 2 0 YwiC-like protein NTF2 PF02136.20 KKK19938.1 - 1.2e-32 113.0 0.0 1.3e-32 112.9 0.0 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain DUF4440 PF14534.6 KKK19938.1 - 0.11 12.9 0.0 0.13 12.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) Surp PF01805.20 KKK19939.1 - 8.7e-11 41.7 0.0 2.2e-10 40.3 0.0 1.8 1 0 0 1 1 1 1 Surp module POTRA_2 PF08479.11 KKK19939.1 - 0.053 13.4 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 POTRA domain, ShlB-type Glycos_transf_2 PF00535.26 KKK19940.1 - 3.4e-35 121.4 0.0 4.1e-35 121.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KKK19940.1 - 1.3e-12 48.2 0.0 1.6e-12 47.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 KKK19940.1 - 9.9e-06 25.2 0.0 1.4e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 KKK19940.1 - 0.0013 18.2 0.0 0.0022 17.5 0.0 1.4 1 1 0 1 1 1 1 Glycosyl transferase family 21 Vps35 PF03635.17 KKK19942.1 - 0 1033.1 0.6 0 1032.9 0.6 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 DUF3907 PF13047.6 KKK19942.1 - 0.084 12.8 0.1 8 6.4 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3907) Spore_coat_CotO PF14153.6 KKK19944.1 - 1.5 8.7 9.3 3.4 7.6 9.3 1.5 1 0 0 1 1 1 0 Spore coat protein CotO CDC45 PF02724.14 KKK19944.1 - 5.4 5.2 7.8 8.3 4.6 7.8 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 KKK19944.1 - 7.4 4.6 15.7 11 4.0 15.7 1.1 1 0 0 1 1 1 0 Nop14-like family DUF1749 PF08538.10 KKK19945.1 - 2.1e-108 362.0 0.0 2.3e-108 361.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.7 KKK19945.1 - 1.6e-05 25.7 0.2 1.9e-05 25.4 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family LIDHydrolase PF10230.9 KKK19945.1 - 0.0015 18.2 0.0 0.27 10.7 0.0 2.2 2 0 0 2 2 2 2 Lipid-droplet associated hydrolase DUF900 PF05990.12 KKK19945.1 - 0.013 15.0 0.0 0.022 14.3 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Hydrolase_4 PF12146.8 KKK19945.1 - 0.014 14.6 0.0 0.025 13.9 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KKK19945.1 - 0.1 12.1 0.0 0.27 10.7 0.0 1.7 1 1 0 1 1 1 0 Prolyl oligopeptidase family DUF2974 PF11187.8 KKK19945.1 - 0.21 11.1 0.0 0.32 10.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Pkinase PF00069.25 KKK19947.1 - 1.2e-19 70.7 0.0 3.6e-10 39.7 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KKK19947.1 - 9.6e-09 34.9 0.4 0.0033 16.7 0.0 3.4 4 0 0 4 4 4 3 Protein tyrosine kinase Kdo PF06293.14 KKK19947.1 - 0.021 14.2 0.3 0.043 13.2 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KKK19947.1 - 0.12 12.3 0.1 0.23 11.3 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Myb_DNA-bind_6 PF13921.6 KKK19948.1 - 0.00079 19.6 0.3 0.0014 18.9 0.3 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain NAPRTase PF04095.16 KKK19959.1 - 2.1e-58 197.8 0.0 3.2e-58 197.2 0.0 1.3 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family NAPRTase_N PF17767.1 KKK19959.1 - 6.2e-32 110.6 0.2 1e-31 109.9 0.2 1.4 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain Fungal_trans PF04082.18 KKK19960.1 - 1.8e-22 79.7 4.4 3.1e-22 78.9 4.4 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Cys_rich_VLP PF14194.6 KKK19961.1 - 0.017 15.3 1.5 0.026 14.6 1.5 1.4 1 0 0 1 1 1 0 Cysteine-rich VLP Tom6 PF17112.5 KKK19962.1 - 4.2e-05 23.0 0.0 5.1e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom6, fungal CTNNBL PF08216.11 KKK19963.1 - 1.9e-39 134.0 1.1 5.6e-39 132.5 0.1 2.4 3 0 0 3 3 3 1 Catenin-beta-like, Arm-motif containing nuclear Arm PF00514.23 KKK19963.1 - 0.00079 19.4 0.7 2.2 8.4 0.0 3.2 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat Mo25 PF08569.11 KKK19963.1 - 0.006 16.0 2.3 0.019 14.3 2.2 1.9 1 1 0 1 1 1 1 Mo25-like Arm_3 PF16186.5 KKK19963.1 - 0.051 13.2 0.6 0.22 11.1 0.6 2.1 1 0 0 1 1 1 0 Atypical Arm repeat RNA_pol_Rpb2_6 PF00562.28 KKK19964.1 - 3.3e-123 411.6 0.0 4.6e-123 411.1 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 KKK19964.1 - 5.3e-61 205.7 0.0 9.6e-61 204.8 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 KKK19964.1 - 3e-46 157.5 0.0 5.6e-46 156.6 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 KKK19964.1 - 5.6e-33 113.2 0.1 1.5e-32 111.8 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.16 KKK19964.1 - 1e-25 89.7 0.5 2.6e-25 88.4 0.1 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.13 KKK19964.1 - 5.6e-24 84.2 0.7 1.5e-23 82.8 0.7 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.17 KKK19964.1 - 5e-22 78.2 0.4 1.7e-21 76.5 0.4 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 AMPK1_CBM PF16561.5 KKK19965.1 - 0.0001 22.4 0.0 0.00019 21.6 0.0 1.4 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase TPR_1 PF00515.28 KKK19966.1 - 3.9e-39 130.9 18.8 3.9e-05 23.3 0.2 8.8 9 0 0 9 9 9 8 Tetratricopeptide repeat STI1 PF17830.1 KKK19966.1 - 1.4e-37 127.4 13.0 9.1e-20 70.3 0.2 3.0 3 0 0 3 3 2 2 STI1 domain TPR_2 PF07719.17 KKK19966.1 - 8.9e-32 106.6 21.6 2.5e-05 24.1 0.3 9.8 9 1 1 10 10 10 6 Tetratricopeptide repeat TPR_11 PF13414.6 KKK19966.1 - 5.9e-17 61.1 17.2 6.7e-05 22.5 0.3 8.1 5 2 3 8 8 8 5 TPR repeat TPR_8 PF13181.6 KKK19966.1 - 4.5e-16 57.6 17.9 0.013 15.7 0.1 7.8 6 1 1 7 7 7 4 Tetratricopeptide repeat TPR_12 PF13424.6 KKK19966.1 - 2.3e-15 56.7 14.1 8.1e-06 26.0 1.3 6.7 6 1 2 8 8 7 4 Tetratricopeptide repeat TPR_19 PF14559.6 KKK19966.1 - 1.4e-12 47.9 13.5 0.025 15.1 0.4 7.2 5 2 2 7 7 6 5 Tetratricopeptide repeat TPR_16 PF13432.6 KKK19966.1 - 1e-11 45.3 12.6 0.016 15.8 4.0 6.6 3 2 2 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 KKK19966.1 - 3.1e-09 36.9 16.7 0.34 11.9 0.5 8.7 7 2 3 10 10 8 2 Tetratricopeptide repeat TPR_9 PF13371.6 KKK19966.1 - 3.4e-09 36.7 7.1 0.00013 22.0 0.2 4.5 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.6 KKK19966.1 - 2e-08 34.1 0.9 6.3 7.4 0.0 6.5 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 KKK19966.1 - 1.2e-07 31.3 11.5 0.013 15.4 0.0 7.8 8 1 1 9 9 8 1 Tetratricopeptide repeat TPR_10 PF13374.6 KKK19966.1 - 4.2e-07 29.6 11.1 3.8 7.5 0.1 7.1 6 1 1 7 7 7 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KKK19966.1 - 5e-05 23.3 0.7 0.16 12.1 0.0 4.8 5 0 0 5 5 5 1 Fis1 C-terminal tetratricopeptide repeat TPR_15 PF13429.6 KKK19966.1 - 0.00019 20.7 8.3 1.8 7.7 0.1 4.8 2 2 4 6 6 6 3 Tetratricopeptide repeat SHNi-TPR PF10516.9 KKK19966.1 - 0.0015 17.9 7.5 2.3 7.7 0.0 5.3 6 0 0 6 6 6 1 SHNi-TPR TPR_6 PF13174.6 KKK19966.1 - 0.0025 18.3 17.0 0.5 11.1 0.0 8.1 8 0 0 8 8 8 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KKK19966.1 - 0.012 15.8 6.4 2.7 8.3 0.1 4.4 3 3 3 6 6 6 0 Anaphase-promoting complex, cyclosome, subunit 3 NARP1 PF12569.8 KKK19966.1 - 0.017 14.0 0.1 0.017 14.0 0.1 3.9 3 2 0 4 4 4 0 NMDA receptor-regulated protein 1 DUF1840 PF08895.11 KKK19966.1 - 0.057 13.8 0.6 0.057 13.8 0.6 4.5 5 1 0 5 5 4 0 Domain of unknown function (DUF1840) TPR_20 PF14561.6 KKK19966.1 - 0.22 11.9 0.1 0.22 11.9 0.1 5.5 4 2 3 7 7 7 0 Tetratricopeptide repeat ING PF12998.7 KKK19967.1 - 8.2e-23 80.9 6.9 1.6e-22 80.0 6.9 1.5 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 KKK19967.1 - 7e-06 25.8 9.5 1.3e-05 25.0 9.5 1.4 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 KKK19967.1 - 0.011 16.0 0.3 0.027 14.7 0.3 1.6 1 0 0 1 1 1 0 PHD-like zinc-binding domain CDC27 PF09507.10 KKK19967.1 - 0.27 10.6 11.9 0.41 10.0 11.9 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DNA_pol_phi PF04931.13 KKK19967.1 - 2.7 6.0 7.5 4.2 5.4 7.5 1.2 1 0 0 1 1 1 0 DNA polymerase phi TFIIA PF03153.13 KKK19967.1 - 5.2 6.9 16.2 8.7 6.2 15.7 1.5 1 1 1 2 2 2 0 Transcription factor IIA, alpha/beta subunit RNA_pol_Rpc34 PF05158.12 KKK19968.1 - 1.1e-119 399.8 0.0 1.2e-119 399.6 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit HTH_46 PF15977.5 KKK19968.1 - 0.034 14.2 0.1 0.074 13.1 0.1 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA binding MarR PF01047.22 KKK19968.1 - 0.069 13.1 0.0 0.24 11.4 0.0 1.9 2 0 0 2 2 2 0 MarR family Na_H_Exchanger PF00999.21 KKK19969.1 - 1.1e-42 146.2 15.7 1.4e-42 145.9 15.7 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family YrhC PF14143.6 KKK19969.1 - 0.011 15.8 0.9 0.17 12.0 0.1 3.2 3 0 0 3 3 3 0 YrhC-like protein PEPCK_ATP PF01293.20 KKK19970.1 - 4.6e-216 718.0 0.0 5.5e-216 717.7 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_25 PF13481.6 KKK19970.1 - 0.094 12.3 0.0 1.8 8.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KKK19970.1 - 0.18 12.0 0.1 0.39 10.9 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KKK19970.1 - 0.19 12.1 0.0 0.39 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain TPR_12 PF13424.6 KKK19971.1 - 1.5e-11 44.4 0.2 3.7e-07 30.3 0.1 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat NB-ARC PF00931.22 KKK19971.1 - 1.2e-09 37.8 0.0 5.3e-09 35.6 0.0 2.1 2 1 0 2 2 2 1 NB-ARC domain AAA_16 PF13191.6 KKK19971.1 - 3.9e-05 24.1 0.4 0.002 18.5 0.0 3.0 3 0 0 3 3 3 1 AAA ATPase domain TPR_1 PF00515.28 KKK19971.1 - 0.0013 18.5 1.2 0.015 15.1 0.1 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 KKK19971.1 - 0.0022 18.0 4.3 1.4 9.2 0.1 5.0 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_10 PF13374.6 KKK19971.1 - 0.0038 17.1 0.2 0.032 14.1 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 KKK19971.1 - 0.0039 17.9 0.8 3 8.9 0.1 4.4 4 2 0 4 4 4 1 Tetratricopeptide repeat TPR_MalT PF17874.1 KKK19971.1 - 0.0057 16.1 0.0 0.18 11.2 0.1 2.2 1 1 1 2 2 2 2 MalT-like TPR region NACHT PF05729.12 KKK19971.1 - 0.013 15.4 0.1 0.13 12.1 0.1 2.6 1 1 0 1 1 1 0 NACHT domain AAA_22 PF13401.6 KKK19971.1 - 0.02 15.2 0.0 0.14 12.4 0.0 2.3 3 0 0 3 3 3 0 AAA domain TPR_7 PF13176.6 KKK19971.1 - 0.027 14.5 0.5 0.87 9.8 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.14 KKK19971.1 - 0.039 14.6 0.7 31 5.6 0.0 3.4 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 KKK19971.1 - 0.042 14.5 1.0 0.042 14.5 1.0 2.4 2 1 0 2 2 2 0 Tetratricopeptide repeat PEX11 PF05648.14 KKK19972.1 - 1.8e-73 246.7 0.5 2.1e-73 246.5 0.5 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Mito_carr PF00153.27 KKK19973.1 - 7.3e-53 176.5 2.8 4.7e-19 68.1 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein zf-Nse PF11789.8 KKK19974.1 - 1.3e-23 82.5 0.1 2.2e-23 81.8 0.1 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 KKK19974.1 - 0.00015 21.7 0.1 0.0026 17.7 0.0 2.4 1 1 1 2 2 2 2 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KKK19974.1 - 0.0067 16.3 0.6 0.14 12.0 0.0 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-MIZ PF02891.20 KKK19974.1 - 0.013 15.2 1.6 0.1 12.4 0.1 2.2 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger Aminotran_1_2 PF00155.21 KKK19975.1 - 2.3e-41 142.2 0.0 3.2e-41 141.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KKK19975.1 - 0.071 11.6 0.0 0.1 11.1 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Copper-fist PF00649.18 KKK19976.1 - 7.9e-22 76.5 2.3 7.9e-22 76.5 2.3 2.0 2 0 0 2 2 2 1 Copper fist DNA binding domain RPN7 PF10602.9 KKK19978.1 - 3.9e-53 179.7 0.4 6e-53 179.1 0.4 1.3 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 KKK19978.1 - 6.8e-16 58.7 0.1 2.1e-15 57.1 0.0 1.9 2 0 0 2 2 2 1 PCI domain TPR_7 PF13176.6 KKK19978.1 - 0.068 13.2 0.0 0.32 11.1 0.0 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat LSM PF01423.22 KKK19979.1 - 4.7e-07 29.4 0.0 6.5e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 LSM domain DUF3237 PF11578.8 KKK19999.1 - 2.9e-06 27.2 0.0 4.6e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) zf-BED PF02892.15 KKK19999.1 - 0.00022 21.2 4.5 0.13 12.3 0.5 2.3 2 0 0 2 2 2 2 BED zinc finger DUF4699 PF15770.5 KKK19999.1 - 0.07 12.9 2.6 0.096 12.4 2.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4699) Zn_Tnp_IS91 PF14319.6 KKK19999.1 - 0.25 11.4 11.3 0.52 10.4 2.2 2.2 2 0 0 2 2 2 0 Transposase zinc-binding domain PyrI_C PF02748.15 KKK19999.1 - 0.49 10.3 6.0 5 7.1 0.5 2.3 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain DUF866 PF05907.13 KKK19999.1 - 0.54 10.1 2.3 5.9 6.8 0.1 2.1 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF866) PPR_2 PF13041.6 KKK20011.1 - 4.3e-09 36.4 0.0 0.012 15.7 0.1 4.1 3 1 1 4 4 4 3 PPR repeat family PPR PF01535.20 KKK20011.1 - 2.3e-07 30.6 0.8 0.096 13.0 0.1 4.3 4 0 0 4 4 4 2 PPR repeat PPR_long PF17177.4 KKK20011.1 - 0.0093 15.4 0.0 0.018 14.4 0.0 1.4 1 0 0 1 1 1 1 Pentacotripeptide-repeat region of PRORP TPR_14 PF13428.6 KKK20011.1 - 0.014 16.2 0.5 6 8.0 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat PPR_3 PF13812.6 KKK20011.1 - 0.033 14.3 0.0 0.16 12.1 0.0 2.1 3 0 0 3 3 3 0 Pentatricopeptide repeat domain Helicase_C PF00271.31 KKK20012.1 - 1.8e-15 57.2 0.0 8.5e-10 39.0 0.0 3.8 3 1 0 3 3 3 2 Helicase conserved C-terminal domain DEAD PF00270.29 KKK20012.1 - 1.8e-11 44.1 0.0 2.7e-07 30.5 0.1 2.5 1 1 1 2 2 2 2 DEAD/DEAH box helicase RecQ_Zn_bind PF16124.5 KKK20012.1 - 9.8e-07 29.4 0.3 9.8e-07 29.4 0.3 2.4 2 0 0 2 2 2 1 RecQ zinc-binding SR-25 PF10500.9 KKK20012.1 - 0.0025 17.5 12.0 0.0025 17.5 12.0 1.8 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein zf-C4H2 PF10146.9 KKK20012.1 - 0.013 15.9 0.2 1.2 9.4 0.0 2.3 2 0 0 2 2 2 0 Zinc finger-containing protein Pex14_N PF04695.13 KKK20012.1 - 0.029 15.0 3.0 2.8 8.6 1.1 2.4 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SUIM_assoc PF16619.5 KKK20012.1 - 0.22 11.6 6.9 0.25 11.5 1.3 2.6 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Herpes_capsid PF06112.11 KKK20012.1 - 1.3 9.0 14.1 2.7 8.1 14.1 1.5 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Chorion_2 PF03964.15 KKK20012.1 - 1.6 9.6 9.3 0.2 12.5 4.5 1.9 2 0 0 2 2 2 0 Chorion family 2 AF-4 PF05110.13 KKK20012.1 - 2.1 6.4 16.9 0.092 10.8 10.7 1.7 2 0 0 2 2 2 0 AF-4 proto-oncoprotein DUF1645 PF07816.11 KKK20012.1 - 2.1 8.9 11.2 0.27 11.8 6.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1645) RAP1 PF07218.11 KKK20012.1 - 5.6 5.1 7.3 8.4 4.5 7.3 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF508 PF04370.12 KKK20012.1 - 8.9 6.0 9.4 16 5.2 9.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF508) SelP_N PF04592.14 KKK20013.1 - 0.063 12.7 1.4 0.11 11.9 1.4 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region DUF4587 PF15248.6 KKK20013.1 - 0.22 12.4 1.4 0.5 11.2 1.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4587) Ydc2-catalyt PF09159.10 KKK20014.1 - 1.2e-80 271.2 0.0 1.5e-80 270.9 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 SAP PF02037.27 KKK20014.1 - 1.7e-05 24.4 0.0 5.9e-05 22.7 0.0 1.9 2 0 0 2 2 2 1 SAP domain Pox_A22 PF04848.13 KKK20014.1 - 0.0033 17.6 0.0 11 6.2 0.0 3.2 3 0 0 3 3 3 1 Poxvirus A22 protein SUIM_assoc PF16619.5 KKK20014.1 - 0.016 15.2 0.3 0.031 14.3 0.3 1.5 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Trypan_PARP PF05887.11 KKK20014.1 - 0.14 12.1 6.4 0.26 11.3 6.4 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Osmo_CC PF08946.10 KKK20015.1 - 0.044 14.0 0.8 0.07 13.4 0.8 1.3 1 0 0 1 1 1 0 Osmosensory transporter coiled coil CTP_transf_like PF01467.26 KKK20016.1 - 2e-05 24.8 0.2 0.00014 22.1 0.0 2.3 3 0 0 3 3 3 1 Cytidylyltransferase-like SOG2 PF10428.9 KKK20017.1 - 2.2e-111 373.6 14.1 1.1e-110 371.3 0.0 4.0 4 1 0 4 4 4 2 RAM signalling pathway protein LRR_8 PF13855.6 KKK20017.1 - 7.2e-17 60.9 14.8 7.8e-10 38.4 2.7 3.2 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 KKK20017.1 - 2.7e-09 37.1 5.9 0.00019 21.7 1.7 3.8 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KKK20017.1 - 0.003 17.5 2.0 17 5.8 0.1 4.4 4 0 0 4 4 4 2 Leucine Rich repeat LRR_1 PF00560.33 KKK20017.1 - 0.015 15.8 4.5 23 6.0 0.1 5.2 5 0 0 5 5 5 0 Leucine Rich Repeat MRP-S25 PF13741.6 KKK20018.1 - 2.7e-83 279.1 9.2 3.1e-83 278.9 9.2 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein S25 MRP-S23 PF10484.9 KKK20018.1 - 0.0044 17.3 1.8 1.1 9.5 0.1 2.5 2 1 0 2 2 2 2 Mitochondrial ribosomal protein S23 hGDE_N PF14699.6 KKK20018.1 - 0.066 13.4 0.7 0.75 10.0 0.0 2.8 3 0 0 3 3 3 0 N-terminal domain from the human glycogen debranching enzyme Tcp11 PF05794.13 KKK20019.1 - 8e-113 377.8 0.6 1e-112 377.5 0.6 1.1 1 0 0 1 1 1 1 T-complex protein 11 Peptidase_S10 PF00450.22 KKK20020.1 - 7.8e-71 239.7 0.1 1.8e-69 235.2 0.1 2.5 1 1 0 1 1 1 1 Serine carboxypeptidase Serglycin PF04360.12 KKK20020.1 - 0.63 10.0 2.3 0.75 9.7 1.0 1.8 2 0 0 2 2 2 0 Serglycin DUF3984 PF13136.6 KKK20021.1 - 2.7e-100 336.0 27.7 2.7e-100 336.0 27.7 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3984) Transposase_24 PF03004.14 KKK20021.1 - 0.0009 19.4 1.3 0.0028 17.7 1.3 1.9 1 0 0 1 1 1 1 Plant transposase (Ptta/En/Spm family) EIIBC-GUT_N PF03612.14 KKK20021.1 - 0.38 10.5 1.8 0.39 10.4 0.3 1.7 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus OTCace_N PF02729.21 KKK20022.1 - 2.1e-44 151.1 0.1 3.9e-44 150.3 0.0 1.5 2 0 0 2 2 2 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.24 KKK20022.1 - 1.1e-43 149.1 0.0 1.7e-43 148.4 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain ALS_ss_C PF10369.9 KKK20023.1 - 3.9e-15 55.8 0.0 7e-14 51.8 0.0 2.3 2 0 0 2 2 2 1 Small subunit of acetolactate synthase ACT PF01842.25 KKK20023.1 - 8.1e-13 47.9 0.1 1.3e-12 47.2 0.1 1.4 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.6 KKK20023.1 - 5.9e-08 32.4 0.0 1.1e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 ACT domain ACT_6 PF13740.6 KKK20023.1 - 0.03 14.3 0.1 6.9 6.7 0.0 2.7 2 0 0 2 2 2 0 ACT domain Limkain-b1 PF11608.8 KKK20023.1 - 0.032 14.3 0.0 0.076 13.1 0.0 1.5 1 0 0 1 1 1 0 Limkain b1 KH_1 PF00013.29 KKK20024.1 - 1.6e-09 37.4 0.0 2.6e-06 27.2 0.0 2.5 2 0 0 2 2 2 2 KH domain Fmp27 PF10344.9 KKK20025.1 - 3.7e-254 845.9 0.0 5e-253 842.2 0.0 2.2 2 0 0 2 2 2 1 Mitochondrial protein from FMP27 Apt1 PF10351.9 KKK20025.1 - 1e-193 644.6 0.9 1e-193 644.6 0.9 3.0 3 0 0 3 3 3 1 Golgi-body localisation protein domain Fmp27_WPPW PF10359.9 KKK20025.1 - 7.8e-173 575.8 4.9 1.5e-172 574.8 4.9 1.5 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.9 KKK20025.1 - 4.2e-59 198.9 0.2 9.2e-59 197.8 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF2405) Fmp27_GFWDK PF10347.9 KKK20025.1 - 4.7e-55 186.0 0.0 1.1e-54 184.7 0.0 1.7 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain Fmp27_SW PF10305.9 KKK20025.1 - 1.8e-32 112.1 0.0 1.3e-30 106.2 0.0 3.3 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain LEA_2 PF03168.13 KKK20027.1 - 1.4e-07 32.0 4.0 0.12 12.9 0.0 5.0 4 1 1 5 5 5 2 Late embryogenesis abundant protein DUF3712 PF12505.8 KKK20027.1 - 8.4e-07 29.3 0.2 7.5e-06 26.2 0.1 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF3712) SET PF00856.28 KKK20030.1 - 9.1e-17 61.9 0.3 4.7e-16 59.6 0.1 2.3 2 1 0 2 2 2 1 SET domain Pre-SET PF05033.16 KKK20030.1 - 4e-12 46.8 3.8 4e-12 46.8 3.8 2.6 2 1 0 2 2 2 1 Pre-SET motif AWS PF17907.1 KKK20030.1 - 0.0042 17.1 1.4 0.0042 17.1 1.4 3.0 4 0 0 4 4 4 1 AWS domain Alveol-reg_P311 PF11092.8 KKK20030.1 - 0.13 12.4 0.0 0.46 10.7 0.0 1.9 1 0 0 1 1 1 0 Neuronal protein 3.1 (p311) Ytp1 PF10355.9 KKK20050.1 - 2.1e-115 384.7 9.6 3e-115 384.2 9.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 KKK20050.1 - 4.1e-20 71.5 10.8 1.7e-18 66.3 2.9 2.8 2 0 0 2 2 2 2 Domain of unknown function (DUF2427) PCI PF01399.27 KKK20051.1 - 2.1e-08 34.6 0.0 4.9e-08 33.4 0.0 1.7 1 0 0 1 1 1 1 PCI domain Rpn9_C PF18261.1 KKK20051.1 - 0.00013 21.4 0.8 0.00032 20.2 0.8 1.6 1 0 0 1 1 1 1 Rpn9 C-terminal helix Gaa1 PF04114.14 KKK20052.1 - 3.8e-176 587.0 1.1 5.7e-176 586.4 1.1 1.3 1 0 0 1 1 1 1 Gaa1-like, GPI transamidase component Rhomboid PF01694.22 KKK20052.1 - 4.1e-14 52.8 8.8 4.1e-14 52.8 8.8 3.2 5 0 0 5 5 5 1 Rhomboid family DLH PF01738.18 KKK20053.1 - 3.7e-32 111.6 0.0 4.3e-32 111.4 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 KKK20053.1 - 0.0024 17.5 0.0 0.0033 17.1 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Acetyltransf_8 PF13523.6 KKK20057.1 - 6.1e-28 97.3 0.5 1.4e-18 66.9 0.0 2.2 1 1 1 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KKK20057.1 - 0.088 13.5 0.2 0.39 11.4 0.1 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Glyco_hydro_98M PF08306.11 KKK20058.1 - 0.046 13.0 0.1 0.078 12.3 0.1 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 98 Mor PF08765.11 KKK20058.1 - 0.17 11.9 0.1 0.37 10.8 0.1 1.5 1 0 0 1 1 1 0 Mor transcription activator family ABC_membrane PF00664.23 KKK20059.1 - 2.9e-92 309.2 20.5 6.6e-51 173.6 3.1 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KKK20059.1 - 4.2e-61 205.4 0.0 1.2e-29 103.6 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KKK20059.1 - 1.1e-16 61.0 0.3 6.7e-05 22.4 0.0 4.3 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KKK20059.1 - 1.3e-08 34.4 0.1 0.0023 17.7 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 KKK20059.1 - 9.2e-08 32.4 1.2 0.039 14.2 0.1 4.2 2 2 1 3 3 3 2 AAA domain AAA_16 PF13191.6 KKK20059.1 - 2.3e-06 28.1 1.0 0.049 14.0 0.0 3.2 2 1 0 2 2 2 2 AAA ATPase domain DUF87 PF01935.17 KKK20059.1 - 1.9e-05 24.9 0.4 0.006 16.7 0.2 2.6 2 1 0 2 2 2 1 Helicase HerA, central domain RsgA_GTPase PF03193.16 KKK20059.1 - 6.6e-05 22.9 0.0 0.064 13.2 0.0 2.6 2 0 0 2 2 2 1 RsgA GTPase APS_kinase PF01583.20 KKK20059.1 - 0.00012 22.0 0.0 0.14 12.1 0.0 2.6 2 0 0 2 2 2 2 Adenylylsulphate kinase AAA_30 PF13604.6 KKK20059.1 - 0.00013 21.8 1.2 0.62 9.7 0.0 3.8 3 1 0 3 3 3 2 AAA domain AAA_18 PF13238.6 KKK20059.1 - 0.0002 21.9 0.0 0.71 10.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.6 KKK20059.1 - 0.00055 20.5 6.4 0.25 11.8 0.1 3.3 3 0 0 3 3 3 2 AAA domain AAA PF00004.29 KKK20059.1 - 0.00065 20.1 0.5 8 6.9 0.2 4.2 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 KKK20059.1 - 0.00086 18.6 0.0 0.84 8.9 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin AAA_33 PF13671.6 KKK20059.1 - 0.0011 19.1 0.0 2.3 8.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 KKK20059.1 - 0.0026 17.3 0.5 2.5 7.6 0.0 3.7 4 0 0 4 4 4 1 AAA domain ABC_ATPase PF09818.9 KKK20059.1 - 0.0041 16.0 0.2 0.18 10.6 0.0 2.5 2 0 0 2 2 2 1 Predicted ATPase of the ABC class DUF3987 PF13148.6 KKK20059.1 - 0.0074 15.3 2.7 0.081 11.9 0.0 2.8 3 0 0 3 3 2 1 Protein of unknown function (DUF3987) KdpD PF02702.17 KKK20059.1 - 0.0075 15.8 0.0 0.25 10.8 0.0 2.4 2 0 0 2 2 2 1 Osmosensitive K+ channel His kinase sensor domain DEAD PF00270.29 KKK20059.1 - 0.022 14.5 0.0 0.38 10.5 0.0 2.8 3 1 0 3 3 3 0 DEAD/DEAH box helicase AAA_7 PF12775.7 KKK20059.1 - 0.025 14.1 0.0 4.3 6.8 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_21 PF13304.6 KKK20059.1 - 0.077 12.8 0.0 5.7 6.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_24 PF13479.6 KKK20059.1 - 0.086 12.6 0.0 6.9 6.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.6 KKK20059.1 - 0.087 12.5 0.6 8.6 5.9 0.0 2.5 3 0 0 3 3 2 0 AAA ATPase domain AAA_5 PF07728.14 KKK20059.1 - 0.099 12.6 0.0 18 5.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Rad17 PF03215.15 KKK20059.1 - 0.13 12.2 0.0 0.76 9.7 0.0 2.1 2 0 0 2 2 2 0 Rad17 P-loop domain NB-ARC PF00931.22 KKK20059.1 - 0.14 11.4 0.0 7.1 5.7 0.0 2.5 3 0 0 3 3 2 0 NB-ARC domain SbcCD_C PF13558.6 KKK20059.1 - 0.15 12.3 2.0 23 5.3 0.1 3.4 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_17 PF13207.6 KKK20059.1 - 0.15 12.5 0.0 18 5.7 0.0 2.8 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 KKK20059.1 - 0.16 12.1 0.0 27 4.9 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase G-alpha PF00503.20 KKK20059.1 - 0.16 11.1 0.0 7 5.7 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit Radial_spoke PF04712.12 KKK20059.1 - 0.26 10.2 5.3 0.38 9.6 5.3 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein Ribosomal_60s PF00428.19 KKK20059.1 - 1.1 9.9 11.1 4.2 8.0 11.1 1.9 1 0 0 1 1 1 0 60s Acidic ribosomal protein CENP-B_dimeris PF09026.10 KKK20059.1 - 2.1 8.8 4.2 5.5 7.5 4.2 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Cad PF03596.13 KKK20059.1 - 6.7 6.6 7.6 0.55 10.1 0.6 2.7 3 0 0 3 3 2 0 Cadmium resistance transporter MFS_1 PF07690.16 KKK20060.1 - 9.6e-25 87.2 44.4 4.3e-23 81.8 43.2 2.8 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KKK20060.1 - 0.00022 19.8 9.2 0.00022 19.8 9.2 2.3 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) TMEM208_SND2 PF05620.11 KKK20060.1 - 1.1 9.0 11.9 0.042 13.6 5.0 2.3 2 0 0 2 2 2 0 SRP-independent targeting protein 2/TMEM208 Ald_Xan_dh_C2 PF02738.18 KKK20061.1 - 6.4e-202 671.9 2.5 9e-202 671.4 2.5 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.21 KKK20061.1 - 1.8e-45 154.7 0.0 3.9e-45 153.6 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Ald_Xan_dh_C PF01315.22 KKK20061.1 - 2.3e-34 118.1 0.0 4.9e-34 117.0 0.0 1.6 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain CO_deh_flav_C PF03450.17 KKK20061.1 - 1.9e-32 111.5 0.0 8.1e-32 109.5 0.0 2.2 2 0 0 2 2 2 1 CO dehydrogenase flavoprotein C-terminal domain Fer2_2 PF01799.20 KKK20061.1 - 1.3e-28 98.8 0.1 2.8e-28 97.7 0.1 1.6 1 0 0 1 1 1 1 [2Fe-2S] binding domain Fer2 PF00111.27 KKK20061.1 - 2.9e-08 33.6 0.1 2.9e-08 33.6 0.1 2.4 3 0 0 3 3 3 1 2Fe-2S iron-sulfur cluster binding domain DUF218 PF02698.17 KKK20061.1 - 0.07 13.2 0.0 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 DUF218 domain Baculo_PEP_C PF04513.12 KKK20062.1 - 0.0086 16.1 7.6 0.15 12.1 0.5 3.3 3 1 1 4 4 4 2 Baculovirus polyhedron envelope protein, PEP, C terminus Abhydrolase_9_N PF15420.6 KKK20062.1 - 0.062 13.3 1.0 0.18 11.8 1.0 1.8 1 0 0 1 1 1 0 Alpha/beta-hydrolase family N-terminus SR-25 PF10500.9 KKK20063.1 - 0.0037 16.9 13.6 0.0037 16.9 13.6 2.2 2 1 0 2 2 2 1 Nuclear RNA-splicing-associated protein CCDC106 PF15794.5 KKK20063.1 - 0.14 11.9 8.7 0.2 11.3 8.7 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 TSGP1 PF07771.11 KKK20063.1 - 1.1 9.4 5.3 1.9 8.7 5.3 1.3 1 0 0 1 1 1 0 Tick salivary peptide group 1 NAD_binding_4 PF07993.12 KKK20064.1 - 5.4e-33 114.3 0.0 7.7e-33 113.7 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein GET2 PF08690.10 KKK20064.1 - 1.6e-10 41.2 0.0 2.7e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 GET complex subunit GET2 3Beta_HSD PF01073.19 KKK20064.1 - 0.00034 19.7 0.0 0.0024 16.9 0.0 2.0 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.10 KKK20064.1 - 0.0034 17.3 0.0 0.0074 16.2 0.0 1.5 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KKK20064.1 - 0.0043 16.5 0.0 0.02 14.4 0.0 1.9 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family AMP-binding PF00501.28 KKK20065.1 - 1.4e-63 215.0 0.0 7.4e-62 209.3 0.0 2.0 1 1 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 KKK20065.1 - 5.9e-15 54.9 0.1 1.5e-14 53.6 0.1 1.8 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus C2 PF00168.30 KKK20066.1 - 1.2e-28 99.4 0.0 6.3e-17 61.8 0.0 2.7 2 0 0 2 2 2 2 C2 domain Reprolysin_5 PF13688.6 KKK20067.1 - 6.4e-61 205.9 9.7 6.4e-61 205.9 9.7 2.5 2 1 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 KKK20067.1 - 2.5e-48 164.4 5.3 4.7e-48 163.5 5.3 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 KKK20067.1 - 2.3e-46 158.2 5.6 2.3e-46 158.2 5.6 1.9 2 1 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.23 KKK20067.1 - 2.3e-17 63.5 33.2 2.3e-17 63.5 33.2 4.9 4 1 1 5 5 5 1 Disintegrin Reprolysin_3 PF13582.6 KKK20067.1 - 2.4e-12 47.5 0.1 2.4e-12 47.5 0.1 1.9 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like ADAM_CR_2 PF17771.1 KKK20067.1 - 6.4e-06 26.6 10.8 6.4e-06 26.6 10.8 5.2 1 1 2 3 3 3 1 ADAM cysteine-rich domain Pep_M12B_propep PF01562.19 KKK20067.1 - 0.004 17.4 0.9 0.0083 16.4 0.1 1.9 2 0 0 2 2 2 1 Reprolysin family propeptide IMS PF00817.20 KKK20068.1 - 2.6e-38 131.4 0.0 1.8e-37 128.7 0.0 2.0 2 0 0 2 2 2 1 impB/mucB/samB family IMS_C PF11799.8 KKK20068.1 - 6.8e-15 55.8 0.3 4.8e-14 53.1 0.2 2.3 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 KKK20068.1 - 0.00017 21.7 0.0 0.00044 20.4 0.0 1.7 1 0 0 1 1 1 1 IMS family HHH motif MgsA_C PF12002.8 KKK20069.1 - 9.4e-59 198.1 0.2 2.4e-58 196.8 0.1 1.7 2 0 0 2 2 2 1 MgsA AAA+ ATPase C terminal AAA_assoc_2 PF16193.5 KKK20069.1 - 2.9e-22 78.8 0.2 8.7e-22 77.3 0.2 1.8 1 0 0 1 1 1 1 AAA C-terminal domain AAA PF00004.29 KKK20069.1 - 6e-15 55.8 0.0 1.4e-14 54.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KKK20069.1 - 1e-10 41.6 0.0 2.1e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 KKK20069.1 - 8.5e-06 25.3 0.1 0.061 12.7 0.0 2.3 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KKK20069.1 - 1.7e-05 24.8 0.0 0.00019 21.5 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 KKK20069.1 - 1.9e-05 24.5 0.0 0.00011 22.0 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KKK20069.1 - 0.00017 21.3 0.0 0.01 15.5 0.0 2.3 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_16 PF13191.6 KKK20069.1 - 0.00044 20.7 0.2 0.2 12.1 0.0 3.0 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 KKK20069.1 - 0.0032 17.7 0.0 0.01 16.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KKK20069.1 - 0.0041 17.5 0.2 0.019 15.3 0.2 1.8 1 1 1 2 2 2 1 AAA domain AAA_14 PF13173.6 KKK20069.1 - 0.013 15.6 0.0 0.025 14.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.6 KKK20069.1 - 0.016 15.3 0.0 0.034 14.3 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain DUF815 PF05673.13 KKK20069.1 - 0.017 14.3 0.0 0.028 13.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) TIP49 PF06068.13 KKK20069.1 - 0.017 14.3 0.0 0.047 12.9 0.0 1.5 1 1 0 1 1 1 0 TIP49 P-loop domain ResIII PF04851.15 KKK20069.1 - 0.021 14.9 0.2 0.81 9.7 0.0 2.2 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit AAA_30 PF13604.6 KKK20069.1 - 0.032 13.9 0.2 0.083 12.6 0.2 1.7 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KKK20069.1 - 0.045 14.0 0.2 0.13 12.5 0.2 1.8 2 0 0 2 2 1 0 AAA domain AAA_18 PF13238.6 KKK20069.1 - 0.046 14.3 0.0 0.087 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain SKI PF01202.22 KKK20069.1 - 0.063 13.4 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 Shikimate kinase Zeta_toxin PF06414.12 KKK20069.1 - 0.087 12.1 0.0 0.2 10.9 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_24 PF13479.6 KKK20069.1 - 0.088 12.5 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain zf-WRNIP1_ubi PF18279.1 KKK20069.1 - 0.13 13.0 0.1 0.36 11.6 0.1 1.9 1 0 0 1 1 1 0 Werner helicase-interacting protein 1 ubiquitin-binding domain RNA_helicase PF00910.22 KKK20069.1 - 0.13 12.6 0.0 0.26 11.7 0.0 1.5 1 0 0 1 1 1 0 RNA helicase CPT PF07931.12 KKK20069.1 - 0.13 12.1 0.1 0.6 9.9 0.0 1.9 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein AAA_29 PF13555.6 KKK20069.1 - 0.17 11.6 0.0 12 5.7 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain TsaE PF02367.17 KKK20069.1 - 0.19 11.7 0.0 0.43 10.6 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE EF-hand_1 PF00036.32 KKK20070.1 - 1e-15 56.0 1.3 2.5e-05 23.5 0.1 3.5 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 KKK20070.1 - 2.2e-15 56.8 2.2 2.9e-09 37.2 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KKK20070.1 - 1.7e-13 49.3 2.7 2.5e-05 23.8 0.2 3.7 4 0 0 4 4 4 2 EF-hand domain EF-hand_8 PF13833.6 KKK20070.1 - 6.7e-11 41.9 0.3 6.5e-08 32.3 0.1 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 KKK20070.1 - 0.17 11.4 6.4 2 8.1 0.1 3.2 3 0 0 3 3 3 0 EF hand EF-hand_4 PF12763.7 KKK20070.1 - 0.2 11.7 0.0 0.49 10.4 0.0 1.6 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand MerR-DNA-bind PF09278.11 KKK20070.1 - 0.4 11.3 3.3 2 9.0 0.2 2.9 3 0 0 3 3 3 0 MerR, DNA binding Ribosomal_60s PF00428.19 KKK20070.1 - 8 7.1 11.6 4.9 7.8 8.5 2.2 2 0 0 2 2 2 0 60s Acidic ribosomal protein Coilin_N PF15862.5 KKK20071.1 - 0.034 13.9 0.0 0.034 13.9 0.0 2.7 3 1 0 3 3 3 0 Coilin N-terminus zf-MYND PF01753.18 KKK20071.1 - 0.07 13.2 8.5 0.21 11.7 8.5 1.9 1 0 0 1 1 1 0 MYND finger Herpes_UL69 PF05459.12 KKK20071.1 - 0.073 12.4 1.3 1.1 8.6 0.1 2.5 3 0 0 3 3 3 0 Herpesvirus transcriptional regulator family Aminotran_1_2 PF00155.21 KKK20072.1 - 2.3e-57 194.8 0.0 4.7e-57 193.8 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KKK20072.1 - 0.0058 15.2 0.0 0.0095 14.5 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 KKK20072.1 - 0.0075 15.6 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 KKK20072.1 - 0.017 14.1 0.0 0.025 13.5 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 KKK20072.1 - 0.02 14.2 0.0 0.033 13.5 0.0 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family RNA_pol_Rpb4 PF03874.16 KKK20074.1 - 1.6e-07 31.7 0.0 0.00089 19.6 0.0 2.4 2 1 0 2 2 2 2 RNA polymerase Rpb4 Dicty_REP PF05086.12 KKK20076.1 - 0.068 11.2 1.0 0.078 10.9 1.0 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein APH PF01636.23 KKK20077.1 - 9.3e-16 58.5 0.2 3.7e-15 56.5 0.1 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.14 KKK20077.1 - 0.018 14.3 0.0 0.033 13.4 0.0 1.4 1 0 0 1 1 1 0 Fructosamine kinase vATP-synt_AC39 PF01992.16 KKK20078.1 - 4.2e-103 345.4 0.0 4.8e-103 345.2 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit Nop PF01798.18 KKK20079.1 - 6.1e-83 277.8 0.1 1.3e-82 276.7 0.1 1.6 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 KKK20079.1 - 5.5e-22 77.9 3.0 5.5e-22 77.9 3.0 2.4 2 0 0 2 2 2 1 NOP5NT (NUC127) domain HWE_HK PF07536.14 KKK20079.1 - 0.057 14.1 1.0 42 4.9 0.0 3.5 3 0 0 3 3 3 0 HWE histidine kinase SGT1 PF07093.11 KKK20079.1 - 3.5 6.0 15.7 5.9 5.2 15.7 1.3 1 0 0 1 1 1 0 SGT1 protein PI3K_1B_p101 PF10486.9 KKK20079.1 - 3.9 5.1 9.4 7.5 4.2 9.4 1.4 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Ribosomal_S15 PF00312.22 KKK20080.1 - 6.6e-28 96.8 1.8 3.1e-27 94.6 0.3 2.7 2 1 1 3 3 3 1 Ribosomal protein S15 Red1 PF07964.11 KKK20081.1 - 0.019 13.3 21.1 0.024 12.9 21.1 1.1 1 0 0 1 1 1 0 Rec10 / Red1 Mitofilin PF09731.9 KKK20081.1 - 1.3 7.7 18.9 1.8 7.3 18.9 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein SWI-SNF_Ssr4 PF08549.10 KKK20081.1 - 1.3 7.5 16.1 1.9 7.0 16.1 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) SOBP PF15279.6 KKK20081.1 - 2.9 8.4 23.9 4.2 7.9 23.9 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein PseudoU_synth_1 PF01416.20 KKK20082.1 - 5.6e-35 120.1 0.0 1e-33 116.0 0.0 2.9 3 1 0 3 3 3 1 tRNA pseudouridine synthase Dynamitin PF04912.14 KKK20082.1 - 0.0062 15.9 0.4 0.0089 15.4 0.4 1.2 1 0 0 1 1 1 1 Dynamitin Pribosyl_synth PF14572.6 KKK20083.1 - 7.6e-40 136.9 2.8 5.6e-35 121.0 0.9 2.3 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.6 KKK20083.1 - 1.5e-32 111.9 0.0 3.2e-32 110.9 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.27 KKK20083.1 - 4.6e-14 52.2 0.6 7.9e-14 51.5 0.6 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 KKK20083.1 - 0.004 16.6 0.3 0.0067 15.9 0.3 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Ribosomal_S2 PF00318.20 KKK20084.1 - 3.3e-26 91.9 0.1 5e-15 55.3 0.1 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 40S_SA_C PF16122.5 KKK20084.1 - 8.1e-07 30.3 16.5 1.5e-06 29.4 16.5 1.4 1 0 0 1 1 1 1 40S ribosomal protein SA C-terminus Ras PF00071.22 KKK20085.1 - 4.8e-18 65.3 0.0 1.2e-17 64.0 0.0 1.6 1 1 0 1 1 1 1 Ras family Roc PF08477.13 KKK20085.1 - 2.7e-05 24.4 0.0 4.7e-05 23.6 0.0 1.4 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 KKK20085.1 - 0.00019 20.7 0.0 0.00019 20.7 0.0 1.1 1 0 0 1 1 1 1 G-protein alpha subunit MCM PF00493.23 KKK20085.1 - 0.002 17.3 0.0 0.0028 16.8 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain AAA_21 PF13304.6 KKK20085.1 - 0.014 15.2 0.1 0.021 14.6 0.1 1.2 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system NACHT PF05729.12 KKK20085.1 - 0.015 15.2 0.1 0.025 14.5 0.1 1.3 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.6 KKK20085.1 - 0.029 14.7 0.0 0.032 14.6 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 KKK20085.1 - 0.043 14.3 0.0 0.052 14.1 0.0 1.3 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 KKK20085.1 - 0.05 13.4 0.1 0.12 12.1 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA_helicase PF00910.22 KKK20085.1 - 0.075 13.4 0.0 0.35 11.3 0.0 1.9 1 1 0 1 1 1 0 RNA helicase AAA_25 PF13481.6 KKK20085.1 - 0.079 12.5 0.2 1.5 8.3 0.1 2.1 2 0 0 2 2 2 0 AAA domain KAP_NTPase PF07693.14 KKK20085.1 - 0.091 12.0 0.0 0.12 11.5 0.0 1.1 1 0 0 1 1 1 0 KAP family P-loop domain Zeta_toxin PF06414.12 KKK20085.1 - 0.15 11.3 0.0 0.3 10.4 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_24 PF13479.6 KKK20085.1 - 0.22 11.2 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain HEM4 PF02602.15 KKK20086.1 - 7.1e-25 87.7 0.0 1e-23 84.0 0.0 2.0 1 1 0 1 1 1 1 Uroporphyrinogen-III synthase HemD Pkinase PF00069.25 KKK20087.1 - 9.6e-68 228.4 0.0 1.2e-67 228.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK20087.1 - 2.5e-32 112.2 0.0 3.3e-32 111.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KKK20087.1 - 0.00036 19.9 0.2 0.00059 19.2 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KKK20087.1 - 0.0029 16.6 0.1 0.005 15.8 0.1 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KKK20087.1 - 0.0096 15.3 0.0 0.018 14.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KKK20087.1 - 0.035 14.0 0.1 0.058 13.3 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KKK20087.1 - 0.073 12.1 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Sec23_trunk PF04811.15 KKK20088.1 - 4.2e-70 236.1 0.0 8.3e-70 235.1 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 KKK20088.1 - 1.6e-22 79.3 0.0 5.6e-22 77.5 0.0 1.9 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 KKK20088.1 - 8.1e-17 61.8 0.0 1.7e-16 60.7 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 KKK20088.1 - 3.1e-11 43.1 3.0 6.1e-11 42.2 3.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 KKK20088.1 - 5.1e-09 35.9 0.0 1.3e-08 34.6 0.0 1.7 2 0 0 2 2 2 1 Gelsolin repeat Kinesin PF00225.23 KKK20089.1 - 1.6e-80 270.6 2.7 1.6e-80 270.6 2.7 2.2 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KKK20089.1 - 4.5e-22 78.6 0.0 1e-21 77.5 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding HHH PF00633.23 KKK20089.1 - 1.4e-06 27.9 0.9 0.042 13.7 0.0 3.2 3 0 0 3 3 3 2 Helix-hairpin-helix motif HHH_5 PF14520.6 KKK20089.1 - 0.00044 20.8 0.0 1.7 9.3 0.0 2.8 2 0 0 2 2 2 2 Helix-hairpin-helix domain TPR_15 PF13429.6 KKK20089.1 - 0.0069 15.6 1.1 0.012 14.9 1.1 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat HHH_3 PF12836.7 KKK20089.1 - 0.027 14.7 1.3 3.9 7.8 0.0 3.1 3 0 0 3 3 3 0 Helix-hairpin-helix motif Spore_YhcN_YlaJ PF09580.10 KKK20089.1 - 0.056 13.5 0.2 0.16 12.1 0.2 1.7 1 0 0 1 1 1 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) DUF2462 PF09495.10 KKK20089.1 - 0.1 13.3 3.4 2 9.2 0.3 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2462) DUF4435 PF14491.6 KKK20089.1 - 0.45 10.4 2.9 3.6 7.4 0.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4435) Ribosomal_S17 PF00366.20 KKK20090.1 - 1.8e-12 47.2 0.4 2.8e-12 46.6 0.4 1.3 1 0 0 1 1 1 1 Ribosomal protein S17 Nucleo_P87 PF07267.11 KKK20090.1 - 0.035 13.0 2.2 0.042 12.7 2.2 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 BUD22 PF09073.10 KKK20090.1 - 0.56 9.5 6.1 9.7 5.4 3.4 2.0 2 0 0 2 2 2 0 BUD22 Cnd1 PF12717.7 KKK20091.1 - 7.8e-05 22.8 0.3 0.78 9.8 0.0 3.3 2 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KKK20091.1 - 0.00057 19.9 0.1 1.8 9.0 0.2 4.5 4 0 0 4 4 4 1 HEAT repeat CLASP_N PF12348.8 KKK20091.1 - 0.00097 18.8 0.3 0.084 12.4 0.3 3.1 2 1 1 3 3 3 1 CLASP N terminal TAN PF11640.8 KKK20091.1 - 0.0011 19.1 0.3 0.0083 16.3 0.3 2.4 1 1 0 1 1 1 1 Telomere-length maintenance and DNA damage repair Adaptin_N PF01602.20 KKK20091.1 - 0.008 14.8 1.2 0.074 11.6 1.2 2.3 1 1 0 1 1 1 1 Adaptin N terminal region MMS19_N PF14500.6 KKK20091.1 - 0.016 14.8 0.4 0.9 9.1 0.3 3.1 2 1 1 3 3 3 0 Dos2-interacting transcription regulator of RNA-Pol-II Syntaxin PF00804.25 KKK20091.1 - 0.016 14.9 3.9 0.053 13.2 3.9 1.8 1 0 0 1 1 1 0 Syntaxin Golgin_A5 PF09787.9 KKK20091.1 - 0.02 14.4 8.5 0.052 13.0 8.5 1.6 1 0 0 1 1 1 0 Golgin subfamily A member 5 PhoU_div PF01865.16 KKK20091.1 - 0.059 12.7 0.3 0.24 10.7 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function DUF47 DUF2353 PF09789.9 KKK20091.1 - 0.44 9.9 9.0 0.62 9.4 7.8 1.7 2 0 0 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) Spc7 PF08317.11 KKK20091.1 - 1.1 8.0 9.9 0.1 11.4 4.6 1.9 2 0 0 2 2 2 0 Spc7 kinetochore protein Atg14 PF10186.9 KKK20091.1 - 1.8 7.6 7.6 4.1 6.4 7.6 1.5 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 ADIP PF11559.8 KKK20091.1 - 2.7 8.1 14.2 8.7 6.4 14.2 1.8 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Mod_r PF07200.13 KKK20091.1 - 2.7 8.1 11.0 0.29 11.3 5.9 2.0 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein UPF0242 PF06785.11 KKK20091.1 - 3.9 7.5 7.7 12 5.9 7.7 1.8 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF724 PF05266.14 KKK20091.1 - 5.4 6.8 8.3 15 5.4 8.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF724) WD40 PF00400.32 KKK20092.1 - 4.3e-41 138.1 19.6 1.3e-06 29.0 0.3 7.8 7 0 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.7 KKK20092.1 - 2.3e-08 33.8 0.1 4.9e-08 32.7 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KKK20092.1 - 1.4e-07 31.2 0.2 3.8e-07 29.8 0.1 1.9 2 0 0 2 2 2 1 F-box domain ANAPC4_WD40 PF12894.7 KKK20092.1 - 8.2e-07 29.2 1.1 2.7 8.4 0.0 5.4 2 2 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KKK20092.1 - 0.0015 17.3 6.6 4.1 5.9 0.1 5.2 6 1 1 7 7 7 2 Nucleoporin Nup120/160 F-box_4 PF15966.5 KKK20092.1 - 0.023 14.6 0.0 0.066 13.1 0.0 1.8 1 0 0 1 1 1 0 F-box CPSF_A PF03178.15 KKK20092.1 - 0.18 11.1 0.0 0.44 9.8 0.0 1.6 1 0 0 1 1 1 0 CPSF A subunit region Clat_adaptor_s PF01217.20 KKK20094.1 - 3.1e-42 143.9 1.1 9.4e-42 142.3 0.0 2.3 3 1 0 3 3 3 1 Clathrin adaptor complex small chain Ribosomal_L7Ae PF01248.26 KKK20094.1 - 4.6e-23 80.8 1.0 8.1e-23 80.0 1.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family CLPTM1 PF05602.12 KKK20094.1 - 0.13 11.2 0.2 0.22 10.5 0.2 1.3 1 0 0 1 1 1 0 Cleft lip and palate transmembrane protein 1 (CLPTM1) MMR_HSR1 PF01926.23 KKK20095.1 - 1.6e-18 66.9 0.0 2.4e-18 66.3 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 KKK20095.1 - 1.1e-05 25.5 0.0 0.00019 21.5 0.0 2.2 1 1 1 2 2 2 1 Dynamin family RsgA_GTPase PF03193.16 KKK20095.1 - 0.00023 21.1 0.2 0.0054 16.7 0.1 2.2 2 0 0 2 2 2 1 RsgA GTPase FeoB_N PF02421.18 KKK20095.1 - 0.00069 19.2 0.0 0.001 18.6 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 KKK20095.1 - 0.0017 17.9 0.0 0.0081 15.7 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AIG1 PF04548.16 KKK20095.1 - 0.008 15.5 0.0 0.013 14.9 0.0 1.3 1 0 0 1 1 1 1 AIG1 family ABC_tran PF00005.27 KKK20095.1 - 0.027 15.0 0.1 0.044 14.3 0.1 1.5 1 1 0 1 1 1 0 ABC transporter SRPRB PF09439.10 KKK20095.1 - 0.045 13.2 0.0 0.061 12.7 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_29 PF13555.6 KKK20095.1 - 0.081 12.7 0.0 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Roc PF08477.13 KKK20095.1 - 0.13 12.5 0.0 0.28 11.4 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Nuc_sug_transp PF04142.15 KKK20096.1 - 3e-77 259.9 5.9 3.9e-77 259.5 5.9 1.0 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 KKK20096.1 - 4.3e-05 23.7 29.2 0.00036 20.7 8.2 2.4 2 1 0 2 2 2 2 EamA-like transporter family TMEM234 PF10639.9 KKK20096.1 - 0.22 11.5 6.9 0.25 11.4 1.0 2.6 2 1 0 2 2 2 0 Putative transmembrane family 234 DEAD PF00270.29 KKK20097.1 - 2.8e-26 92.3 0.1 5.5e-26 91.4 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KKK20097.1 - 1.9e-15 57.3 0.0 3.5e-15 56.4 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Sec63 PF02889.16 KKK20097.1 - 5.1e-12 45.5 0.0 2e-09 37.0 0.0 2.2 1 1 0 2 2 2 2 Sec63 Brl domain Helicase_C PF00271.31 KKK20097.1 - 2.3e-08 34.4 0.0 4e-06 27.1 0.0 2.8 2 1 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 KKK20097.1 - 1.2e-05 25.6 0.1 5.2e-05 23.5 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KKK20097.1 - 0.00085 19.1 0.0 0.0015 18.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KKK20097.1 - 0.00086 19.7 0.1 0.0029 17.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain Helicase_RecD PF05127.14 KKK20097.1 - 0.022 14.6 0.0 0.062 13.2 0.0 1.8 2 0 0 2 2 2 0 Helicase T2SSE PF00437.20 KKK20097.1 - 0.053 12.6 0.0 0.11 11.5 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein UvrD-helicase PF00580.21 KKK20097.1 - 0.096 12.2 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain HHH_5 PF14520.6 KKK20097.1 - 0.15 12.7 0.0 0.45 11.1 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix domain HORMA PF02301.18 KKK20098.1 - 8.6e-60 201.9 0.0 1.5e-59 201.1 0.0 1.3 1 0 0 1 1 1 1 HORMA domain PHD PF00628.29 KKK20098.1 - 0.0055 16.6 7.1 0.011 15.6 7.1 1.5 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 KKK20098.1 - 0.13 11.9 3.1 0.31 10.6 3.1 1.7 1 0 0 1 1 1 0 PHD-finger LRR_6 PF13516.6 KKK20100.1 - 1.1e-08 34.5 1.3 0.0074 16.3 0.0 4.2 4 0 0 4 4 4 3 Leucine Rich repeat LRR_4 PF12799.7 KKK20100.1 - 5.1e-07 29.9 1.6 0.0014 19.0 0.1 2.9 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KKK20100.1 - 3.4e-05 23.5 3.0 1.8 8.4 0.0 4.2 3 1 0 4 4 4 3 Leucine rich repeat LRR_1 PF00560.33 KKK20100.1 - 0.00046 20.4 0.1 5.7 7.9 0.0 3.9 3 0 0 3 3 3 2 Leucine Rich Repeat Acid_PPase PF12689.7 KKK20101.1 - 5.2e-71 237.9 0.0 6.1e-71 237.7 0.0 1.0 1 0 0 1 1 1 1 Acid Phosphatase Aconitase PF00330.20 KKK20102.1 - 1.5e-150 502.2 0.0 2.1e-150 501.8 0.0 1.2 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KKK20102.1 - 3.2e-43 147.2 0.0 5.7e-43 146.4 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain Mito_carr PF00153.27 KKK20103.1 - 4.8e-48 161.0 1.0 1.1e-20 73.3 0.0 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein Glyco_transf_20 PF00982.21 KKK20104.1 - 2.9e-200 666.0 0.0 3.3e-200 665.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glyco_transf_5 PF08323.11 KKK20104.1 - 0.0068 16.1 0.1 0.021 14.5 0.1 1.7 1 1 0 1 1 1 1 Starch synthase catalytic domain BLACT_WH PF17778.1 KKK20105.1 - 8.8e-18 64.0 0.3 2.5e-17 62.6 0.0 1.9 2 0 0 2 2 2 1 Beta-lactamase associated winged helix domain Lactamase_B PF00753.27 KKK20105.1 - 2.1e-15 57.2 5.0 9.1e-14 51.9 4.9 2.2 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KKK20105.1 - 2.2e-07 30.6 0.6 4.4e-07 29.6 0.6 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain ABC_membrane PF00664.23 KKK20107.1 - 1.8e-39 136.1 11.1 2.3e-39 135.7 11.1 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 KKK20107.1 - 5.8e-35 120.8 0.0 1.2e-34 119.8 0.0 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KKK20107.1 - 8.4e-05 22.1 0.1 0.083 12.3 0.0 2.5 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KKK20107.1 - 0.00089 19.5 0.3 0.0046 17.2 0.1 2.3 2 1 0 2 2 1 1 AAA domain AAA_16 PF13191.6 KKK20107.1 - 0.0011 19.4 0.0 0.0022 18.4 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain ABC_ATPase PF09818.9 KKK20107.1 - 0.0012 17.8 0.0 0.012 14.5 0.0 2.1 2 0 0 2 2 2 1 Predicted ATPase of the ABC class AAA_21 PF13304.6 KKK20107.1 - 0.0021 17.9 0.0 0.017 14.9 0.0 2.2 1 1 1 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system ATP-synt_ab PF00006.25 KKK20107.1 - 0.0032 17.2 0.0 0.0067 16.1 0.0 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain GPAT_N PF14829.6 KKK20107.1 - 0.0032 17.4 0.0 5.6 7.0 0.0 3.2 3 0 0 3 3 3 1 Glycerol-3-phosphate acyltransferase N-terminal AAA_14 PF13173.6 KKK20107.1 - 0.0051 16.9 0.0 0.083 12.9 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_23 PF13476.6 KKK20107.1 - 0.01 16.3 0.0 0.029 14.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KKK20107.1 - 0.012 15.3 0.1 0.027 14.2 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA PF00004.29 KKK20107.1 - 0.012 16.0 0.0 0.11 12.9 0.0 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 KKK20107.1 - 0.013 15.4 0.0 0.041 13.8 0.0 1.8 2 0 0 2 2 2 0 Rad17 P-loop domain RsgA_GTPase PF03193.16 KKK20107.1 - 0.016 15.1 0.0 0.11 12.4 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase AAA_33 PF13671.6 KKK20107.1 - 0.017 15.3 0.0 0.99 9.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 KKK20107.1 - 0.023 14.9 0.0 0.087 13.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KKK20107.1 - 0.031 13.6 0.4 0.45 9.8 0.0 2.8 3 0 0 3 3 3 0 Zeta toxin IstB_IS21 PF01695.17 KKK20107.1 - 0.057 13.1 0.6 9.9 5.9 0.0 3.0 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_10 PF12846.7 KKK20107.1 - 0.093 11.6 0.5 0.29 10.0 0.0 2.0 2 1 0 2 2 2 0 AAA-like domain MMR_HSR1 PF01926.23 KKK20107.1 - 0.093 12.8 1.0 0.19 11.8 0.0 2.1 2 0 0 2 2 1 0 50S ribosome-binding GTPase AAA_18 PF13238.6 KKK20107.1 - 0.16 12.6 0.0 0.61 10.6 0.0 2.1 2 0 0 2 2 1 0 AAA domain SbcCD_C PF13558.6 KKK20107.1 - 0.27 11.5 2.6 1.6 9.0 0.5 2.9 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Rad54_N PF08658.10 KKK20108.1 - 2.2e-59 200.7 1.4 4.2e-58 196.5 1.0 2.3 2 0 0 2 2 2 1 Rad54 N terminal SNF2_N PF00176.23 KKK20108.1 - 8.8e-57 192.4 0.0 1.4e-56 191.7 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KKK20108.1 - 1.8e-15 57.2 0.0 5.6e-15 55.6 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KKK20108.1 - 2.4e-06 27.6 0.0 5.2e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 KKK20108.1 - 0.0015 17.8 0.0 0.0093 15.2 0.0 2.2 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 SWI2_SNF2 PF18766.1 KKK20108.1 - 0.082 12.6 0.0 0.38 10.4 0.0 2.1 2 1 0 2 2 2 0 SWI2/SNF2 ATPase Vac14_Fig4_bd PF11916.8 KKK20109.1 - 7.6e-81 270.0 8.6 7.6e-81 270.0 8.6 1.9 2 0 0 2 2 2 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.7 KKK20109.1 - 2e-43 146.9 0.0 7.8e-41 138.6 0.0 4.0 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 KKK20109.1 - 9.4e-09 35.6 2.9 0.0049 17.4 0.0 4.9 5 1 1 6 6 6 2 HEAT-like repeat HEAT PF02985.22 KKK20109.1 - 6.4e-07 29.1 1.0 0.0011 19.1 0.0 4.6 4 0 0 4 4 4 1 HEAT repeat Cnd1 PF12717.7 KKK20109.1 - 2.4e-05 24.4 1.8 0.032 14.3 0.7 2.7 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KKK20109.1 - 0.00064 20.1 0.9 2.2 8.8 0.0 4.6 4 2 1 5 5 5 1 HEAT repeats IBN_N PF03810.19 KKK20109.1 - 0.013 15.4 0.4 0.16 11.9 0.0 3.0 2 1 0 2 2 2 0 Importin-beta N-terminal domain Arm PF00514.23 KKK20109.1 - 0.015 15.4 0.0 15 5.8 0.0 4.8 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat RCDG1 PF15725.5 KKK20109.1 - 2.7 8.5 8.4 0.26 11.7 1.2 2.7 2 0 0 2 2 2 0 Renal cancer differentiation gene 1 protein AIM24 PF01987.17 KKK20110.1 - 9.5e-40 136.5 0.0 1.3e-39 136.1 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 MFS_1 PF07690.16 KKK20111.1 - 4e-25 88.5 52.0 3.4e-23 82.1 34.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KKK20111.1 - 1.2e-05 24.4 21.9 0.00013 20.9 2.3 2.8 1 1 1 3 3 3 2 Sugar (and other) transporter Fungal_trans PF04082.18 KKK20121.1 - 2.9e-22 79.0 3.2 4.7e-21 75.0 0.0 2.8 3 0 0 3 3 3 2 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK20121.1 - 0.15 12.2 6.8 0.27 11.4 6.8 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Cu-oxidase_3 PF07732.15 KKK20122.1 - 2.5e-33 114.6 0.0 7.9e-33 113.0 0.0 1.9 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 KKK20122.1 - 3.1e-30 104.7 3.1 1.2e-23 83.3 0.8 3.4 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 KKK20122.1 - 6.8e-16 58.8 0.0 3.5e-15 56.5 0.0 2.2 1 1 0 1 1 1 1 Multicopper oxidase Utp14 PF04615.13 KKK20125.1 - 2.1 6.8 24.1 2.5 6.6 24.1 1.0 1 0 0 1 1 1 0 Utp14 protein GREB1 PF15782.5 KKK20125.1 - 5.6 3.9 31.3 6.9 3.6 31.3 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer NAD_binding_5 PF07994.12 KKK20126.1 - 2.1e-144 480.8 0.1 2.5e-144 480.6 0.1 1.1 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.17 KKK20126.1 - 6.5e-46 155.1 0.4 1.2e-45 154.2 0.4 1.5 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase LIM PF00412.22 KKK20127.1 - 1.4e-18 66.8 15.8 1.9e-11 44.0 2.2 2.8 3 1 0 3 3 3 2 LIM domain Cytochrom_c3_2 PF14537.6 KKK20127.1 - 1 9.9 5.0 3.4 8.2 5.0 2.0 1 0 0 1 1 1 0 Cytochrome c3 Cytochrome_C7 PF14522.6 KKK20127.1 - 2.3 8.3 8.3 0.24 11.5 3.3 1.9 2 0 0 2 2 2 0 Cytochrome c7 and related cytochrome c ADH_N PF08240.12 KKK20128.1 - 4.6e-25 87.6 1.0 9.4e-25 86.6 1.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KKK20128.1 - 5.6e-19 68.4 0.6 1.1e-18 67.4 0.6 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KKK20128.1 - 0.00079 18.8 1.4 0.0014 17.9 1.4 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Sacchrp_dh_NADP PF03435.18 KKK20128.1 - 0.0027 17.9 0.1 0.0054 17.0 0.1 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Glu_dehyd_C PF16912.5 KKK20128.1 - 0.0032 17.0 0.1 0.024 14.1 0.1 2.0 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 KKK20128.1 - 0.0094 17.0 0.0 0.018 16.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Pep_deformylase PF01327.21 KKK20128.1 - 0.19 11.3 0.0 0.66 9.6 0.0 1.8 2 0 0 2 2 2 0 Polypeptide deformylase Arf PF00025.21 KKK20129.1 - 2e-25 89.3 0.0 4.6e-25 88.1 0.0 1.7 1 1 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KKK20129.1 - 1.8e-07 31.4 0.0 3.5e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KKK20129.1 - 0.00018 21.2 0.0 0.00028 20.5 0.0 1.3 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 KKK20129.1 - 0.0032 16.9 0.0 0.0062 16.0 0.0 1.5 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 KKK20129.1 - 0.014 14.6 1.5 0.46 9.6 0.1 2.7 2 1 1 3 3 3 0 G-protein alpha subunit RhoGAP PF00620.27 KKK20130.1 - 9.3e-39 132.7 0.0 1.5e-38 132.0 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain Allexi_40kDa PF05549.11 KKK20131.1 - 0.0032 17.0 6.0 0.055 13.0 1.1 2.4 2 0 0 2 2 2 2 Allexivirus 40kDa protein PIG-F PF06699.11 KKK20132.1 - 1.7e-65 220.6 2.2 2.1e-65 220.2 2.2 1.1 1 0 0 1 1 1 1 GPI biosynthesis protein family Pig-F UQ_con PF00179.26 KKK20133.1 - 1.3e-41 141.5 0.0 1.4e-41 141.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KKK20133.1 - 0.00033 20.4 0.0 0.00067 19.4 0.0 1.5 1 1 0 1 1 1 1 Prokaryotic E2 family B UFC1 PF08694.11 KKK20133.1 - 0.059 13.0 0.0 0.075 12.7 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 RWD PF05773.22 KKK20133.1 - 0.098 12.9 0.1 0.15 12.4 0.1 1.4 1 0 0 1 1 1 0 RWD domain Copper-fist PF00649.18 KKK20134.1 - 1.7e-14 53.0 2.8 3e-14 52.2 2.8 1.4 1 0 0 1 1 1 1 Copper fist DNA binding domain HhH-GPD PF00730.25 KKK20135.1 - 4e-20 72.3 0.0 1.1e-19 70.9 0.0 1.7 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 KKK20135.1 - 2.2e-06 27.2 0.0 5.1e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif AAA_11 PF13086.6 KKK20137.1 - 4.4e-62 210.2 0.4 1.8e-61 208.2 0.4 2.1 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.6 KKK20137.1 - 4e-57 193.1 0.0 6.7e-57 192.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KKK20137.1 - 8.4e-14 51.7 0.0 1.6e-12 47.6 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KKK20137.1 - 5.6e-09 36.5 0.0 1.8e-08 34.8 0.0 2.0 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 KKK20137.1 - 2.6e-07 30.6 0.0 0.054 13.2 0.0 3.3 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.9 KKK20137.1 - 1.2e-05 24.7 0.3 0.00012 21.5 0.3 2.1 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Helicase_RecD PF05127.14 KKK20137.1 - 6.8e-05 22.8 0.0 0.16 11.8 0.0 2.9 3 0 0 3 3 3 2 Helicase ResIII PF04851.15 KKK20137.1 - 7.7e-05 22.8 0.0 0.00025 21.1 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.21 KKK20137.1 - 0.00039 20.0 0.3 0.003 17.2 0.2 2.2 1 1 1 2 2 2 1 UvrD/REP helicase N-terminal domain AAA_22 PF13401.6 KKK20137.1 - 0.00043 20.6 0.2 0.014 15.7 0.2 2.6 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 KKK20137.1 - 0.00052 19.5 0.0 0.021 14.3 0.0 2.6 2 0 0 2 2 2 1 PhoH-like protein DEAD PF00270.29 KKK20137.1 - 0.00056 19.7 0.1 0.0082 15.9 0.1 2.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase Flavi_DEAD PF07652.14 KKK20137.1 - 0.0018 18.2 0.1 0.014 15.4 0.1 2.3 2 0 0 2 2 2 1 Flavivirus DEAD domain T2SSE PF00437.20 KKK20137.1 - 0.0027 16.8 0.0 0.0046 16.1 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein UvrD_C_2 PF13538.6 KKK20137.1 - 0.0032 17.2 0.1 0.23 11.3 0.0 2.4 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA PF00004.29 KKK20137.1 - 0.007 16.8 0.0 0.038 14.4 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 KKK20137.1 - 0.0076 16.0 0.0 0.032 14.0 0.0 2.0 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_16 PF13191.6 KKK20137.1 - 0.0094 16.3 0.1 0.023 15.1 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.6 KKK20137.1 - 0.014 15.1 0.0 0.038 13.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KKK20137.1 - 0.018 14.7 0.3 0.26 10.8 0.0 2.8 2 2 1 3 3 3 0 AAA domain 4HB_MCP_1 PF12729.7 KKK20137.1 - 0.05 13.2 0.1 0.1 12.1 0.1 1.4 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction AAA_5 PF07728.14 KKK20137.1 - 0.051 13.6 0.1 0.77 9.8 0.0 2.8 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) PSK_trans_fac PF07704.11 KKK20137.1 - 0.053 14.3 1.4 5.6 7.8 1.7 2.7 2 0 0 2 2 2 0 Rv0623-like transcription factor TrwB_AAD_bind PF10412.9 KKK20137.1 - 0.065 12.1 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain UvrD_C PF13361.6 KKK20137.1 - 0.085 12.2 2.1 6.1 6.1 0.0 3.0 2 2 0 3 3 3 0 UvrD-like helicase C-terminal domain PIF1 PF05970.14 KKK20137.1 - 0.12 11.5 0.0 4.5 6.3 0.0 2.4 2 1 0 2 2 2 0 PIF1-like helicase Herpes_ori_bp PF02399.15 KKK20137.1 - 0.14 10.2 0.0 0.23 9.5 0.0 1.2 1 0 0 1 1 1 0 Origin of replication binding protein Glyco_hydro_72 PF03198.14 KKK20138.1 - 4.4e-139 463.1 5.7 5.2e-139 462.9 5.7 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.18 KKK20138.1 - 2.9e-06 26.9 0.1 2.3e-05 24.0 0.1 2.2 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) PBP PF01161.20 KKK20139.1 - 2.6e-19 69.9 0.0 3.4e-19 69.5 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein zf-Tim10_DDP PF02953.15 KKK20140.1 - 6.7e-20 70.5 4.4 9.6e-20 70.0 4.4 1.3 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.13 KKK20140.1 - 0.0061 16.3 3.1 0.59 9.8 0.3 2.0 1 1 1 2 2 2 2 Eukaryotic protein of unknown function (DUF842) TAF6_C PF07571.13 KKK20140.1 - 0.047 14.0 0.0 0.079 13.3 0.0 1.3 1 1 0 1 1 1 0 TAF6 C-terminal HEAT repeat domain Peptidase_M16_C PF05193.21 KKK20154.1 - 2.5e-54 184.1 0.0 6.8e-54 182.7 0.0 1.8 2 0 0 2 2 2 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 KKK20154.1 - 1.5e-41 141.8 0.0 3.2e-40 137.5 0.0 2.3 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) AMP-binding PF00501.28 KKK20154.1 - 1.9e-37 128.9 0.0 3.5e-37 128.0 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 KKK20154.1 - 3.6e-11 42.8 1.0 7.9e-11 41.7 1.0 1.6 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 KKK20154.1 - 0.0005 21.0 0.0 0.0027 18.6 0.0 2.4 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain DUF4211 PF13926.6 KKK20155.1 - 3.8e-41 140.5 0.0 8.3e-41 139.4 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4211) DUF2046 PF09755.9 KKK20155.1 - 0.12 11.6 8.9 0.092 12.0 0.7 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein H4 (DUF2046) Toxin_14 PF07829.11 KKK20155.1 - 0.4 10.7 5.1 0.84 9.6 5.1 1.5 1 0 0 1 1 1 0 Alpha-A conotoxin PIVA-like protein Tom22 PF04281.13 KKK20156.1 - 3.1e-52 176.0 1.6 3.5e-52 175.9 1.6 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 HLH PF00010.26 KKK20157.1 - 1.7e-13 50.3 0.5 3.5e-13 49.3 0.5 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Sugar_tr PF00083.24 KKK20158.1 - 3.3e-100 336.1 23.2 3.8e-100 335.9 23.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKK20158.1 - 9e-30 103.8 30.0 8.5e-22 77.5 4.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1980 PF09323.10 KKK20158.1 - 0.01 15.8 0.0 0.032 14.2 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) IBR PF01485.21 KKK20163.1 - 4.3e-22 78.1 49.0 7.3e-12 45.3 8.9 4.4 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain zf-RING_2 PF13639.6 KKK20163.1 - 1.8e-05 25.0 4.8 1.8e-05 25.0 4.8 4.0 2 1 1 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.25 KKK20163.1 - 0.00015 21.6 5.1 0.00015 21.6 5.1 4.5 3 1 1 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KKK20163.1 - 0.0032 17.3 6.8 0.0032 17.3 6.8 4.9 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KKK20163.1 - 0.011 15.7 8.5 0.011 15.7 8.5 3.8 2 1 1 3 3 3 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 KKK20163.1 - 0.017 15.2 4.4 0.017 15.2 4.4 3.9 3 1 0 3 3 3 0 RING-type zinc-finger UN_NPL4 PF11543.8 KKK20163.1 - 0.026 15.0 0.0 0.051 14.1 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Trp_syntA PF00290.20 KKK20163.1 - 0.22 10.3 0.0 0.39 9.5 0.0 1.3 1 0 0 1 1 1 0 Tryptophan synthase alpha chain APH PF01636.23 KKK20164.1 - 3.7e-10 40.1 0.0 2.2e-09 37.6 0.0 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KKK20164.1 - 0.044 13.1 0.0 6.5 6.0 0.0 2.3 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 KKK20170.1 - 4.4e-13 49.2 0.0 6.7e-13 48.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK20170.1 - 3.9e-06 26.3 0.0 7.5e-06 25.4 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KKK20170.1 - 0.001 19.1 0.1 0.0017 18.3 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family eIF3m_C_helix PF18005.1 KKK20170.1 - 0.44 10.3 1.1 0.64 9.8 0.0 1.8 2 0 0 2 2 2 0 eIF3 subunit M, C-terminal helix Polyketide_cyc2 PF10604.9 KKK20171.1 - 8.9e-07 29.3 6.6 1.1e-05 25.7 6.6 2.5 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 KKK20171.1 - 0.0034 17.6 2.7 0.0056 16.9 2.6 1.6 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport AHSA1 PF08327.11 KKK20171.1 - 0.0085 16.3 1.8 0.045 14.0 1.9 2.2 1 1 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein CRISPR_assoc PF08798.11 KKK20171.1 - 0.028 14.5 1.0 0.034 14.2 1.0 1.2 1 0 0 1 1 1 0 CRISPR associated protein JAB PF01398.21 KKK20172.1 - 1.6e-15 57.1 0.0 3e-15 56.2 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease USP8_dimer PF08969.11 KKK20172.1 - 8.1e-10 38.9 0.2 1.5e-09 38.1 0.2 1.4 1 0 0 1 1 1 1 USP8 dimerisation domain Prok-JAB PF14464.6 KKK20172.1 - 5.3e-05 23.0 0.0 0.00016 21.4 0.0 1.8 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain TLD PF07534.16 KKK20173.1 - 1.7e-07 31.6 0.0 2.8e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 TLD Herpes_pp85 PF04637.12 KKK20173.1 - 9.7 4.5 5.7 13 4.0 5.7 1.2 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) RrnaAD PF00398.20 KKK20174.1 - 0.00011 21.4 0.0 0.00019 20.6 0.0 1.4 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase ApbA_C PF08546.11 KKK20174.1 - 0.022 15.0 0.1 0.046 13.9 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA C terminal DUF848 PF05852.11 KKK20174.1 - 0.024 14.8 1.1 0.04 14.0 1.1 1.3 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) DLP_helical PF18709.1 KKK20174.1 - 0.11 11.7 0.6 0.14 11.3 0.6 1.1 1 0 0 1 1 1 0 Dynamin-like helical domain DUF4665 PF15679.5 KKK20174.1 - 0.13 12.9 0.3 0.42 11.3 0.1 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4665) Mito_carr PF00153.27 KKK20188.1 - 7.3e-60 198.9 2.5 1.9e-19 69.3 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein TNT PF14021.6 KKK20190.1 - 1.7e-33 115.0 0.1 3.5e-33 114.0 0.0 1.5 2 0 0 2 2 2 1 Tuberculosis necrotizing toxin RTA1 PF04479.13 KKK20191.1 - 1.3e-71 240.5 5.1 1.9e-71 240.0 5.1 1.1 1 0 0 1 1 1 1 RTA1 like protein PhrC_PhrF PF11131.8 KKK20191.1 - 0.077 12.6 0.4 0.29 10.8 0.4 1.9 1 0 0 1 1 1 0 Rap-phr extracellular signalling UQ_con PF00179.26 KKK20192.1 - 1.1e-43 148.2 0.0 1.3e-43 148.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KKK20192.1 - 1.8 8.9 3.8 3.2 8.1 3.8 1.6 1 1 0 1 1 1 0 RWD domain NAD_binding_4 PF07993.12 KKK20193.1 - 1.5e-35 122.6 0.0 2e-35 122.2 0.0 1.1 1 0 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.15 KKK20193.1 - 1e-06 28.1 0.0 1.5e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 KKK20193.1 - 0.052 13.4 0.0 0.085 12.8 0.0 1.3 1 0 0 1 1 1 0 KR domain Zn_clus PF00172.18 KKK20194.1 - 4.7e-10 39.4 9.5 9.5e-10 38.4 9.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KKK20194.1 - 0.00011 21.2 0.7 0.00017 20.6 0.7 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Peptidase_C14 PF00656.22 KKK20194.1 - 0.00027 21.0 0.0 0.00063 19.8 0.0 1.6 1 0 0 1 1 1 1 Caspase domain Raptor_N PF14538.6 KKK20194.1 - 0.098 12.6 0.0 0.24 11.4 0.0 1.6 1 0 0 1 1 1 0 Raptor N-terminal CASPase like domain Glyco_trans_1_4 PF13692.6 KKK20195.1 - 4.2e-08 33.7 0.0 7.2e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 KKK20195.1 - 5.2e-07 29.3 0.0 8.9e-07 28.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 KKK20195.1 - 2.9e-05 24.4 0.0 5.1e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KKK20195.1 - 0.011 15.8 0.2 0.029 14.4 0.2 1.8 1 0 0 1 1 1 0 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 KKK20195.1 - 0.013 15.9 0.0 0.033 14.6 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferase 4-like domain Cation_efflux PF01545.21 KKK20196.1 - 1.5e-45 155.4 12.7 1.5e-45 155.4 12.7 2.3 3 0 0 3 3 3 1 Cation efflux family ADH_N PF08240.12 KKK20197.1 - 9.8e-06 25.4 0.0 2.6e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KKK20197.1 - 0.00047 20.1 0.1 0.0008 19.4 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Abhydrolase_3 PF07859.13 KKK20198.1 - 1.2e-48 165.8 0.1 1.8e-48 165.2 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KKK20198.1 - 2.5e-08 33.3 1.1 6.2e-08 32.0 1.1 1.5 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 KKK20198.1 - 0.095 12.2 0.2 4.8 6.6 0.1 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family Methyltransf_23 PF13489.6 KKK20199.1 - 0.0043 16.9 0.0 0.0043 16.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KKK20199.1 - 0.056 12.8 0.0 0.073 12.4 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) TFIIIC_delta PF12657.7 KKK20200.1 - 1.5e-44 152.2 0.3 2.6e-44 151.4 0.3 1.4 1 0 0 1 1 1 1 Transcription factor IIIC subunit delta N-term zf-TFIIIC PF12660.7 KKK20200.1 - 3.4e-32 110.4 2.5 6.9e-32 109.4 2.5 1.5 1 0 0 1 1 1 1 Putative zinc-finger of transcription factor IIIC complex Type2_restr_D3 PF16902.5 KKK20200.1 - 0.29 11.1 0.4 0.72 9.8 0.1 1.8 2 0 0 2 2 2 0 Type-2 restriction enzyme D3 domain Kinesin PF00225.23 KKK20201.1 - 4.7e-111 370.9 0.1 1e-110 369.8 0.1 1.6 1 0 0 1 1 1 1 Kinesin motor domain UQ_con PF00179.26 KKK20201.1 - 7.2e-49 165.0 0.0 1.6e-48 163.9 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Microtub_bd PF16796.5 KKK20201.1 - 8.3e-25 87.5 0.0 2.4e-24 86.0 0.0 1.8 1 0 0 1 1 1 1 Microtubule binding DinB_2 PF12867.7 KKK20201.1 - 0.042 14.4 0.3 0.46 11.0 0.0 2.9 3 0 0 3 3 3 0 DinB superfamily DUF1398 PF07166.11 KKK20201.1 - 0.061 13.4 0.0 0.2 11.7 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1398) STPPase_N PF16891.5 KKK20201.1 - 0.1 13.1 1.6 21 5.7 0.2 3.0 2 0 0 2 2 2 0 Serine-threonine protein phosphatase N-terminal domain His_Phos_1 PF00300.22 KKK20202.1 - 0.00097 18.9 0.1 2.2 7.9 0.0 3.2 3 0 0 3 3 3 3 Histidine phosphatase superfamily (branch 1) p450 PF00067.22 KKK20203.1 - 1.9e-12 46.7 0.1 2.2e-11 43.2 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 PCI PF01399.27 KKK20204.1 - 0.035 14.6 0.0 10 6.7 0.0 2.9 3 0 0 3 3 3 0 PCI domain 5_nucleotid_C PF02872.18 KKK20205.1 - 3e-38 131.5 0.0 5e-38 130.8 0.0 1.3 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 KKK20205.1 - 0.00027 21.5 0.5 0.001 19.6 0.0 2.1 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase EMP70 PF02990.16 KKK20206.1 - 1.3e-201 670.8 1.3 1.6e-201 670.5 1.3 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 Sas10_Utp3 PF04000.15 KKK20207.1 - 5.4e-16 59.0 0.2 5.4e-16 59.0 0.2 2.0 2 0 0 2 2 2 1 Sas10/Utp3/C1D family EF-hand_1 PF00036.32 KKK20209.1 - 1.9e-25 86.5 11.4 3.8e-08 32.3 0.1 4.8 5 0 0 5 5 5 4 EF hand EF-hand_6 PF13405.6 KKK20209.1 - 2.5e-25 86.2 5.4 3.7e-06 26.4 0.1 5.3 4 1 1 5 5 5 4 EF-hand domain EF-hand_7 PF13499.6 KKK20209.1 - 5.9e-25 87.5 8.2 1.9e-16 60.3 1.0 3.3 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 KKK20209.1 - 2.7e-17 61.4 11.9 0.00015 21.1 0.4 4.7 5 0 0 5 5 5 4 EF hand EF-hand_8 PF13833.6 KKK20209.1 - 1.2e-15 57.0 12.1 5.1e-06 26.2 1.1 4.1 2 2 1 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.7 KKK20209.1 - 2.8e-10 40.1 6.8 0.0037 17.2 0.2 4.0 1 1 3 4 4 4 3 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 KKK20209.1 - 0.00012 22.3 0.8 0.024 15.0 0.1 3.3 2 1 1 3 3 3 2 EF-hand domain EF-hand_10 PF14788.6 KKK20209.1 - 0.0011 18.8 1.0 0.28 11.1 0.0 3.5 3 1 0 3 3 3 1 EF hand SPARC_Ca_bdg PF10591.9 KKK20209.1 - 0.006 16.9 1.8 2.1 8.7 0.3 3.1 2 1 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region DUF1679 PF07914.11 KKK20209.1 - 0.033 13.0 0.6 2.8 6.7 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) Caleosin PF05042.13 KKK20209.1 - 0.38 10.7 3.6 25 4.7 0.0 3.5 2 1 2 4 4 4 0 Caleosin related protein FAD_binding_3 PF01494.19 KKK20210.1 - 7.3e-35 120.8 0.0 8.4e-35 120.6 0.0 1.0 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KKK20210.1 - 7.7e-08 32.3 0.1 0.0053 16.4 0.0 2.1 1 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KKK20210.1 - 0.00014 21.3 0.1 0.14 11.3 0.1 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KKK20210.1 - 0.00017 20.8 0.1 0.023 13.8 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox PF00070.27 KKK20210.1 - 0.0036 17.8 0.0 1.9 9.1 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KKK20210.1 - 0.017 14.0 0.0 0.017 14.0 0.0 1.1 1 0 0 1 1 1 0 Tryptophan halogenase FAD_oxidored PF12831.7 KKK20210.1 - 0.024 14.0 0.0 0.055 12.8 0.0 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KKK20210.1 - 0.036 14.3 0.0 0.08 13.2 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Fungal_trans PF04082.18 KKK20211.1 - 4.2e-07 29.3 0.0 6.7e-07 28.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK20211.1 - 1.5e-06 28.2 7.1 2.9e-06 27.3 7.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BCMA-Tall_bind PF09257.10 KKK20211.1 - 4 7.6 9.7 3.8 7.7 0.2 2.6 2 0 0 2 2 2 0 BCMA, TALL-1 binding Epimerase PF01370.21 KKK20212.1 - 3.3e-10 39.8 0.1 5.2e-09 35.9 0.0 2.4 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KKK20212.1 - 5.7e-05 22.8 0.0 0.00028 20.5 0.0 2.0 1 1 1 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.6 KKK20212.1 - 0.00032 20.7 0.0 0.0011 18.9 0.0 2.0 1 1 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 KKK20212.1 - 0.0013 17.9 0.0 0.002 17.3 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Sugar_tr PF00083.24 KKK20213.1 - 5.5e-91 305.7 20.7 6.8e-91 305.4 20.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKK20213.1 - 2.6e-16 59.5 53.3 1.3e-15 57.2 27.5 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1700 PF08006.11 KKK20213.1 - 0.1 12.1 2.0 1.7 8.1 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1700) DUF2070 PF09843.9 KKK20213.1 - 1.1 7.5 6.4 0.19 10.0 0.4 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2070) Dioxygenase_C PF00775.21 KKK20214.1 - 1.2e-09 37.8 0.2 2e-09 37.1 0.2 1.2 1 0 0 1 1 1 1 Dioxygenase Hemerythrin PF01814.23 KKK20215.1 - 1.9e-10 41.4 0.2 2.8e-10 40.9 0.2 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain DHquinase_I PF01487.15 KKK20221.1 - 4.6e-35 121.9 0.0 7.3e-35 121.3 0.0 1.3 1 0 0 1 1 1 1 Type I 3-dehydroquinase Shikimate_dh_N PF08501.11 KKK20221.1 - 1.3e-20 73.4 0.1 2.9e-20 72.3 0.1 1.6 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain SKI PF01202.22 KKK20221.1 - 3.9e-19 69.3 0.5 7.3e-19 68.4 0.0 1.7 2 0 0 2 2 2 1 Shikimate kinase SDH_C PF18317.1 KKK20221.1 - 2.3e-09 36.9 0.1 4.8e-09 35.8 0.1 1.6 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain Shikimate_DH PF01488.20 KKK20221.1 - 6e-07 29.6 0.0 1.5e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase AAA_28 PF13521.6 KKK20221.1 - 0.0013 19.0 0.0 0.0032 17.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KKK20221.1 - 0.011 15.9 0.0 0.023 14.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KKK20221.1 - 0.027 14.9 0.1 0.45 10.9 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain F420_oxidored PF03807.17 KKK20221.1 - 0.083 13.5 0.0 2 9.1 0.0 2.5 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent AAA PF00004.29 KKK20221.1 - 0.21 12.0 0.0 0.37 11.2 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Fungal_trans PF04082.18 KKK20222.1 - 2.6e-21 75.8 0.0 4.6e-21 75.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK20222.1 - 2.8e-08 33.7 12.9 4.4e-08 33.1 12.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HofP PF10748.9 KKK20223.1 - 0.098 12.2 0.0 0.24 11.0 0.0 1.6 1 0 0 1 1 1 0 DNA utilization proteins HofP DUF3405 PF11885.8 KKK20224.1 - 8.3e-233 773.7 0.4 9.8e-233 773.4 0.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) DUF4692 PF15763.5 KKK20224.1 - 0.25 11.8 2.2 0.42 11.1 2.2 1.3 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) Sod_Cu PF00080.20 KKK20225.1 - 4.1e-10 40.0 0.0 6.2e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Inositol_P PF00459.25 KKK20226.1 - 2.4e-83 279.8 0.0 2.7e-83 279.6 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family DHquinase_II PF01220.19 KKK20227.1 - 9.6e-64 213.2 0.1 1.1e-63 213.0 0.1 1.0 1 0 0 1 1 1 1 Dehydroquinase class II Sugar_tr PF00083.24 KKK20228.1 - 6.2e-139 463.7 21.1 7.1e-139 463.5 21.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKK20228.1 - 4e-29 101.7 63.7 2.3e-26 92.6 35.5 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Shikimate_dh_N PF08501.11 KKK20229.1 - 3.2e-24 85.0 0.0 5.5e-24 84.2 0.0 1.4 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.20 KKK20229.1 - 0.0003 20.8 0.0 0.00052 20.1 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase SDH_C PF18317.1 KKK20229.1 - 0.00081 19.1 0.0 0.0018 18.0 0.0 1.6 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain B12-binding PF02310.19 KKK20229.1 - 0.12 12.4 0.0 11 6.1 0.0 2.6 2 0 0 2 2 2 0 B12 binding domain AP_endonuc_2 PF01261.24 KKK20230.1 - 3.1e-29 101.9 0.4 4.6e-29 101.4 0.4 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel CHORD PF04968.12 KKK20231.1 - 1.7e-50 169.6 21.9 9.6e-27 93.5 7.4 2.2 2 0 0 2 2 2 2 CHORD CS PF04969.16 KKK20231.1 - 7.1e-14 52.6 0.1 1.1e-13 52.0 0.1 1.3 1 0 0 1 1 1 1 CS domain Pheromone PF08015.11 KKK20231.1 - 0.02 15.9 0.5 0.048 14.7 0.5 1.6 1 0 0 1 1 1 0 Fungal mating-type pheromone BTK PF00779.19 KKK20231.1 - 0.27 11.1 12.2 0.28 11.0 1.4 2.9 3 0 0 3 3 3 0 BTK motif Aminotran_3 PF00202.21 KKK20232.1 - 1.3e-110 369.9 0.0 1.6e-110 369.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 KKK20232.1 - 6.9e-05 22.2 0.0 0.00011 21.6 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class I and II Choline_kinase PF01633.20 KKK20233.1 - 9.8e-46 156.0 0.0 2.4e-44 151.5 0.0 2.1 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.23 KKK20233.1 - 2.3e-09 37.5 0.6 7.5e-09 35.9 0.4 1.9 2 1 0 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.20 KKK20233.1 - 0.14 11.4 0.0 0.61 9.4 0.0 1.9 1 1 0 1 1 1 0 Ecdysteroid kinase DUF836 PF05768.14 KKK20234.1 - 4e-12 46.4 0.0 4.9e-12 46.1 0.0 1.1 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Glutaredoxin PF00462.24 KKK20234.1 - 0.1 12.9 0.1 0.15 12.3 0.1 1.4 1 0 0 1 1 1 0 Glutaredoxin DUF1674 PF07896.12 KKK20235.1 - 5.9e-19 68.3 1.7 5.9e-19 68.3 1.7 2.2 2 1 1 3 3 3 1 Protein of unknown function (DUF1674) MARVEL PF01284.23 KKK20237.1 - 0.0019 18.3 15.1 0.0061 16.6 15.4 1.6 1 1 0 1 1 1 1 Membrane-associating domain Kinocilin PF15033.6 KKK20237.1 - 0.34 10.6 2.9 0.31 10.7 1.7 1.6 1 1 0 1 1 1 0 Kinocilin protein FAD_binding_4 PF01565.23 KKK20238.1 - 6.4e-20 71.3 0.7 1.1e-19 70.6 0.4 1.5 2 0 0 2 2 2 1 FAD binding domain BolA PF01722.18 KKK20239.1 - 2.4e-29 101.4 1.3 3e-29 101.1 1.3 1.1 1 0 0 1 1 1 1 BolA-like protein RNB PF00773.19 KKK20240.1 - 1.2e-49 169.4 0.0 5.7e-37 127.8 0.0 2.3 2 0 0 2 2 2 2 RNB domain Glyco_hydro_7 PF00840.20 KKK20241.1 - 4.7e-141 470.5 12.5 4.5e-117 391.4 11.3 2.0 1 1 1 2 2 2 2 Glycosyl hydrolase family 7 TPR_10 PF13374.6 KKK20242.1 - 6.1e-34 114.9 1.2 2.1e-12 46.5 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 KKK20242.1 - 8.6e-28 96.4 0.3 2.2e-12 47.1 0.1 3.2 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KKK20242.1 - 2.8e-07 30.1 1.0 0.031 14.4 0.1 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 KKK20242.1 - 1.7e-05 24.5 0.1 0.03 14.3 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 KKK20242.1 - 1.9e-05 24.3 0.2 0.091 12.6 0.0 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 KKK20242.1 - 0.00025 21.2 0.5 4 8.0 0.0 3.6 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_4 PF07721.14 KKK20242.1 - 0.0056 17.2 0.0 3.1 8.7 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat N1221 PF07923.13 KKK20242.1 - 0.097 11.8 0.0 0.15 11.2 0.0 1.4 1 0 0 1 1 1 0 N1221-like protein TPR_6 PF13174.6 KKK20242.1 - 0.17 12.6 0.3 26 5.8 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 KKK20242.1 - 0.17 12.6 0.0 3 8.6 0.0 2.4 1 1 0 1 1 1 0 Tetratricopeptide repeat Fungal_trans_2 PF11951.8 KKK20243.1 - 3.4e-07 29.4 1.0 6e-07 28.6 0.3 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK20243.1 - 3.2e-06 27.2 9.2 6.3e-06 26.2 9.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HEAT_2 PF13646.6 KKK20243.1 - 0.015 15.7 0.0 0.034 14.5 0.0 1.5 1 0 0 1 1 1 0 HEAT repeats MFS_1 PF07690.16 KKK20244.1 - 4.9e-13 48.7 11.8 1.3e-12 47.3 11.8 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily SNARE PF05739.19 KKK20245.1 - 3e-10 39.9 0.5 3e-10 39.9 0.5 2.0 2 0 0 2 2 1 1 SNARE domain Syntaxin PF00804.25 KKK20245.1 - 1.1e-07 31.7 11.5 1.1e-07 31.7 11.5 1.7 2 0 0 2 2 2 1 Syntaxin Use1 PF09753.9 KKK20245.1 - 9.4e-06 25.5 4.3 1.3e-05 25.0 4.3 1.2 1 0 0 1 1 1 1 Membrane fusion protein Use1 Prominin PF05478.11 KKK20245.1 - 0.0013 16.8 2.4 0.0013 16.8 2.4 1.4 1 1 0 1 1 1 1 Prominin LMBR1 PF04791.16 KKK20245.1 - 0.0051 15.8 1.6 0.0063 15.5 1.6 1.1 1 0 0 1 1 1 1 LMBR1-like membrane protein Syntaxin_2 PF14523.6 KKK20245.1 - 0.0069 16.7 10.6 0.02 15.2 3.2 2.8 2 2 0 2 2 2 1 Syntaxin-like protein MCPsignal PF00015.21 KKK20245.1 - 0.0084 15.9 6.1 0.023 14.5 3.5 2.3 1 1 0 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF2935 PF11155.8 KKK20245.1 - 0.011 16.1 0.1 0.51 10.7 0.6 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF2935) DUF2207 PF09972.9 KKK20245.1 - 0.013 14.3 0.7 0.37 9.5 0.0 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) HisKA_3 PF07730.13 KKK20245.1 - 0.017 15.7 12.0 0.26 11.8 0.1 4.0 3 2 1 4 4 4 0 Histidine kinase CD225 PF04505.12 KKK20245.1 - 0.024 14.7 0.6 0.061 13.5 0.6 1.7 1 0 0 1 1 1 0 Interferon-induced transmembrane protein VitD-bind_III PF09164.10 KKK20245.1 - 0.12 12.3 0.1 0.29 11.1 0.1 1.6 1 0 0 1 1 1 0 Vitamin D binding protein, domain III T2SSF PF00482.23 KKK20245.1 - 0.15 12.0 4.9 1.6 8.7 0.4 2.4 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F Syntaxin-6_N PF09177.11 KKK20245.1 - 0.17 12.5 8.8 4.2 8.0 1.0 3.4 1 1 2 3 3 3 0 Syntaxin 6, N-terminal MCU PF04678.13 KKK20245.1 - 0.37 10.9 8.2 0.14 12.3 0.9 2.3 1 1 1 2 2 2 0 Mitochondrial calcium uniporter Synaptobrevin PF00957.21 KKK20245.1 - 0.48 10.2 3.5 0.23 11.3 0.5 2.1 2 0 0 2 2 2 0 Synaptobrevin TetR_C_15 PF17918.1 KKK20245.1 - 0.6 10.9 3.7 16 6.3 0.2 2.4 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain SKA1 PF07160.12 KKK20245.1 - 0.8 9.5 9.2 0.45 10.3 1.3 2.4 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 1 GP41 PF00517.17 KKK20245.1 - 1.8 8.4 6.9 1.2 9.0 3.7 2.4 2 1 0 2 2 2 0 Retroviral envelope protein CwsA PF10814.8 KKK20245.1 - 2.3 8.4 8.6 5.1 7.3 7.1 2.3 1 1 1 2 2 2 0 Cell wall synthesis protein CwsA Mobilization_B PF17511.2 KKK20245.1 - 3.1 8.2 12.7 0.17 12.3 1.9 3.0 1 1 2 3 3 3 0 Mobilization protein B AKNA PF12443.8 KKK20245.1 - 3.3 8.4 7.8 1.2 9.8 0.3 3.3 1 1 1 3 3 3 0 AT-hook-containing transcription factor DUF1664 PF07889.12 KKK20245.1 - 6.3 6.9 8.8 4.9 7.2 1.5 3.0 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) AMP-binding PF00501.28 KKK20246.1 - 9.6e-66 222.1 0.0 1.3e-65 221.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KKK20246.1 - 3.8e-12 47.0 0.0 7.4e-12 46.1 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Cys_Met_Meta_PP PF01053.20 KKK20247.1 - 6.1e-62 209.3 0.0 1.1e-61 208.6 0.0 1.4 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 KKK20247.1 - 0.013 14.5 0.0 0.025 13.5 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class-V ThiS PF02597.20 KKK20248.1 - 0.17 12.6 0.0 0.2 12.3 0.0 1.1 1 0 0 1 1 1 0 ThiS family FYVE PF01363.21 KKK20249.1 - 1.8e-20 72.9 1.0 1.8e-20 72.9 1.0 3.5 4 0 0 4 4 4 1 FYVE zinc finger Zn_clus PF00172.18 KKK20249.1 - 6.1e-05 23.1 9.8 6.1e-05 23.1 9.8 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KKK20249.1 - 8.7e-05 21.7 0.0 0.00032 19.8 0.0 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain zf-RING_11 PF17123.5 KKK20249.1 - 0.11 12.3 2.4 0.15 11.8 0.2 2.4 2 0 0 2 2 2 0 RING-like zinc finger Zn-C2H2_12 PF18112.1 KKK20249.1 - 5.4 7.6 7.9 13 6.4 0.1 3.3 3 0 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain TRP PF06011.12 KKK20250.1 - 4e-43 147.7 20.7 4.6e-35 121.2 17.8 2.1 1 1 1 2 2 2 2 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 KKK20250.1 - 8.2e-23 81.3 0.1 1.3e-22 80.7 0.1 1.3 1 0 0 1 1 1 1 ML-like domain DUF4381 PF14316.6 KKK20250.1 - 1.3 9.2 7.4 0.24 11.6 1.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) Stevor PF17410.2 KKK20250.1 - 5.9 6.3 7.7 1.9 8.0 1.2 2.2 2 0 0 2 2 2 0 Subtelomeric Variable Open Reading frame NB-ARC PF00931.22 KKK20251.1 - 9.3e-11 41.4 0.0 1.4e-10 40.8 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain PNP_UDP_1 PF01048.20 KKK20251.1 - 8.4e-09 35.0 0.5 6.6e-08 32.1 0.5 2.3 1 1 0 1 1 1 1 Phosphorylase superfamily NACHT PF05729.12 KKK20251.1 - 1.8e-05 24.7 0.0 3.9e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KKK20251.1 - 3.2e-05 24.4 0.0 8.6e-05 23.0 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KKK20251.1 - 0.019 15.2 0.0 0.11 12.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KKK20251.1 - 0.094 12.4 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain TrwB_AAD_bind PF10412.9 KKK20251.1 - 0.16 10.9 0.0 0.33 9.8 0.0 1.5 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain CNH PF00780.22 KKK20252.1 - 2.1e-68 230.9 0.0 3.4e-68 230.2 0.0 1.3 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.20 KKK20252.1 - 3e-32 112.3 0.7 6.4e-32 111.3 0.7 1.6 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.6 KKK20252.1 - 5.2e-11 42.8 0.0 3.1e-10 40.3 0.0 2.4 1 1 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 KKK20252.1 - 0.0059 17.1 0.0 0.026 15.0 0.0 2.1 2 0 0 2 2 2 1 PH domain TPK_B1_binding PF04265.14 KKK20253.1 - 0.029 14.1 0.0 0.081 12.6 0.0 1.7 1 0 0 1 1 1 0 Thiamin pyrophosphokinase, vitamin B1 binding domain TPP_enzyme_N PF02776.18 KKK20254.1 - 5e-33 114.1 0.6 8.5e-33 113.4 0.0 1.7 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain ADH_N PF08240.12 KKK20254.1 - 1.9e-25 88.9 0.4 3.8e-25 87.9 0.4 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KKK20254.1 - 2.9e-24 85.5 0.1 8.5e-24 84.0 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase TPP_enzyme_M PF00205.22 KKK20254.1 - 2.7e-21 75.8 0.0 6.7e-20 71.2 0.0 2.6 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 KKK20254.1 - 7.2e-18 64.8 0.7 3.3e-17 62.7 0.0 2.5 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain ADH_zinc_N_2 PF13602.6 KKK20254.1 - 0.0059 17.7 0.0 0.015 16.3 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 KKK20254.1 - 0.048 13.1 0.0 0.09 12.2 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase DUF2284 PF10050.9 KKK20254.1 - 0.053 13.3 0.2 1.8 8.3 0.0 2.3 2 0 0 2 2 2 0 Predicted metal-binding protein (DUF2284) TNT PF14021.6 KKK20255.1 - 7.2e-32 109.8 0.0 1.1e-31 109.2 0.0 1.3 1 0 0 1 1 1 1 Tuberculosis necrotizing toxin RabGAP-TBC PF00566.18 KKK20256.1 - 1.3e-47 162.3 0.0 2.6e-47 161.3 0.0 1.5 1 0 0 1 1 1 1 Rab-GTPase-TBC domain GRAM PF02893.20 KKK20256.1 - 0.0037 17.1 0.0 0.008 16.0 0.0 1.5 1 0 0 1 1 1 1 GRAM domain EF-hand_6 PF13405.6 KKK20256.1 - 0.007 16.2 0.7 0.042 13.8 0.3 2.7 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.6 KKK20256.1 - 0.091 13.2 0.1 0.6 10.6 0.1 2.5 2 1 0 2 2 2 0 EF-hand domain pair EF-hand_1 PF00036.32 KKK20256.1 - 0.12 12.0 0.3 1.1 8.9 1.1 2.2 2 0 0 2 2 2 0 EF hand PikAIV_N PF18605.1 KKK20256.1 - 3.1 7.5 5.2 0.44 10.2 0.3 2.1 2 0 0 2 2 2 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain adh_short_C2 PF13561.6 KKK20258.1 - 1e-35 123.4 0.5 1.4e-34 119.7 0.5 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KKK20258.1 - 6.1e-27 94.3 1.3 2.5e-26 92.4 1.3 1.8 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KKK20258.1 - 3.1e-06 27.2 0.1 5.7e-06 26.4 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KKK20258.1 - 0.078 12.4 0.2 0.19 11.2 0.2 1.8 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF1772 PF08592.11 KKK20259.1 - 0.0003 21.1 0.1 0.00055 20.3 0.1 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF1772) MFS_1 PF07690.16 KKK20260.1 - 4.6e-37 127.7 50.1 7e-37 127.2 41.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KKK20260.1 - 5.8e-11 41.9 14.3 5.8e-11 41.9 14.3 3.3 3 0 0 3 3 3 2 Sugar (and other) transporter Glyoxalase PF00903.25 KKK20261.1 - 0.028 14.6 0.0 0.055 13.7 0.0 1.5 1 1 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily SUR7 PF06687.12 KKK20262.1 - 9.3e-18 64.6 3.6 1.1e-17 64.4 3.6 1.0 1 0 0 1 1 1 1 SUR7/PalI family Fig1 PF12351.8 KKK20262.1 - 0.0013 18.7 3.8 0.0013 18.7 3.8 1.5 2 0 0 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 DUF4282 PF14110.6 KKK20262.1 - 0.036 14.8 0.4 0.036 14.8 0.4 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4282) 2OG-FeII_Oxy_2 PF13532.6 KKK20263.1 - 1.2e-28 100.6 0.0 2.4e-28 99.7 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Glyco_hydro_127 PF07944.12 KKK20263.1 - 3e-23 82.1 0.0 4.6e-20 71.6 0.0 2.1 2 0 0 2 2 2 2 Beta-L-arabinofuranosidase, GH127 AhpC-TSA_2 PF13911.6 KKK20264.1 - 1.6e-17 63.7 0.0 2.4e-17 63.1 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.21 KKK20264.1 - 0.0026 17.6 0.0 0.0058 16.5 0.0 1.5 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KKK20264.1 - 0.13 11.9 0.0 0.28 10.9 0.0 1.5 1 1 0 1 1 1 0 Redoxin Exo_endo_phos PF03372.23 KKK20265.1 - 7.4e-05 22.4 0.0 0.00021 20.9 0.0 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family SF3b1 PF08920.10 KKK20272.1 - 2e-34 118.6 13.7 2.1e-33 115.3 9.3 3.2 1 1 1 2 2 2 1 Splicing factor 3B subunit 1 HEAT_2 PF13646.6 KKK20272.1 - 1.5e-11 44.5 8.2 0.22 12.0 0.1 8.8 7 1 3 10 10 10 3 HEAT repeats HEAT_EZ PF13513.6 KKK20272.1 - 4.1e-10 39.9 5.4 0.012 16.1 0.0 7.0 6 1 1 7 7 6 2 HEAT-like repeat HEAT PF02985.22 KKK20272.1 - 4.2e-09 35.9 9.7 0.031 14.5 0.5 8.7 9 0 0 9 9 9 2 HEAT repeat Vac14_Fab1_bd PF12755.7 KKK20272.1 - 2.6e-05 24.7 0.3 1.7 9.3 0.0 5.1 4 1 1 5 5 5 1 Vacuolar 14 Fab1-binding region UNC45-central PF11701.8 KKK20272.1 - 9.7e-05 22.4 0.0 0.00038 20.5 0.0 1.9 2 0 0 2 2 2 1 Myosin-binding striated muscle assembly central DUF3385 PF11865.8 KKK20272.1 - 0.00017 21.5 1.9 0.26 11.2 0.0 5.1 4 1 1 5 5 5 1 Domain of unknown function (DUF3385) Adaptin_N PF01602.20 KKK20272.1 - 0.00018 20.2 0.5 0.17 10.4 0.2 3.5 2 2 1 3 3 3 1 Adaptin N terminal region NUC173 PF08161.12 KKK20272.1 - 0.00022 21.0 0.1 1.2 8.7 0.0 3.9 5 0 0 5 5 5 2 NUC173 domain Cnd1 PF12717.7 KKK20272.1 - 0.00045 20.3 5.5 0.39 10.8 0.1 5.6 4 2 2 6 6 6 1 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 KKK20272.1 - 0.0018 17.9 0.1 0.96 9.0 0.0 3.3 3 0 0 3 3 3 1 CLASP N terminal MMS19_C PF12460.8 KKK20272.1 - 0.0078 15.4 0.0 0.3 10.2 0.0 2.8 2 1 0 2 2 2 1 RNAPII transcription regulator C-terminal IFRD PF05004.13 KKK20272.1 - 0.01 15.0 0.0 0.29 10.2 0.0 2.6 2 0 0 2 2 2 0 Interferon-related developmental regulator (IFRD) TAF6_C PF07571.13 KKK20272.1 - 0.058 13.7 0.0 1 9.7 0.0 2.9 2 0 0 2 2 2 0 TAF6 C-terminal HEAT repeat domain DRIM PF07539.12 KKK20272.1 - 0.12 10.7 0.2 6.8 4.9 0.0 3.5 2 1 2 4 4 4 0 Down-regulated in metastasis EF-1_beta_acid PF10587.9 KKK20272.1 - 0.92 10.0 3.1 5.2 7.6 3.1 2.4 1 0 0 1 1 1 0 Eukaryotic elongation factor 1 beta central acidic region RR_TM4-6 PF06459.12 KKK20272.1 - 2.2 8.0 4.4 4.5 7.0 4.3 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Sec1 PF00995.23 KKK20273.1 - 2.9e-114 383.4 0.0 3.2e-114 383.2 0.0 1.0 1 0 0 1 1 1 1 Sec1 family DUF1481 PF07356.12 KKK20274.1 - 0.027 14.3 1.1 0.027 14.3 1.1 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF1481) UQ_con PF00179.26 KKK20275.1 - 1.1e-27 96.3 0.0 1.3e-27 96.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KKK20275.1 - 0.0098 16.2 0.3 0.022 15.1 0.2 1.7 1 1 0 1 1 1 1 RWD domain Prok-E2_A PF14457.6 KKK20275.1 - 0.083 12.5 0.0 0.11 12.1 0.0 1.1 1 0 0 1 1 1 0 Prokaryotic E2 family A RNA_pol_A_bac PF01000.26 KKK20276.1 - 1.1e-26 93.4 0.0 2e-26 92.5 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 KKK20276.1 - 9.5e-18 63.4 0.0 1.4e-17 62.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Complex1_49kDa PF00346.19 KKK20277.1 - 8.5e-123 408.7 0.0 1.3e-122 408.2 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases PF00374.19 KKK20277.1 - 0.0012 17.8 0.0 0.0018 17.3 0.0 1.3 1 0 0 1 1 1 1 Nickel-dependent hydrogenase Telomere_reg-2 PF10193.9 KKK20278.1 - 9.4e-32 109.7 0.0 2.7e-31 108.2 0.0 1.9 1 0 0 1 1 1 1 Telomere length regulation protein TLP-20 PF06088.11 KKK20278.1 - 0.24 11.3 1.6 7.5 6.4 0.0 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) TFIIA PF03153.13 KKK20278.1 - 0.27 11.2 3.3 0.62 10.0 3.3 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ThiF PF00899.21 KKK20279.1 - 1.4e-47 162.1 0.0 1.1e-35 123.2 0.0 2.1 1 1 1 2 2 2 2 ThiF family E2_bind PF08825.10 KKK20279.1 - 4.7e-30 103.6 0.1 7.1e-30 103.0 0.1 1.3 1 0 0 1 1 1 1 E2 binding domain Shikimate_DH PF01488.20 KKK20279.1 - 0.00058 19.9 0.1 0.003 17.6 0.0 2.0 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase E1_UFD PF09358.10 KKK20279.1 - 0.049 14.3 0.0 0.15 12.8 0.0 1.8 1 0 0 1 1 1 0 Ubiquitin fold domain PglD_N PF17836.1 KKK20279.1 - 0.17 12.6 0.1 1.6 9.4 0.7 2.5 2 1 0 2 2 2 0 PglD N-terminal domain UBA_e1_thiolCys PF10585.9 KKK20279.1 - 1.4 8.8 3.5 19 5.1 0.1 2.2 1 1 1 2 2 2 0 Ubiquitin-activating enzyme active site Sugar_tr PF00083.24 KKK20295.1 - 5.2e-26 91.5 22.7 2.7e-17 62.8 6.0 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KKK20295.1 - 9.2e-16 57.7 32.6 1.7e-08 33.8 17.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily ketoacyl-synt PF00109.26 KKK20296.1 - 2.2e-76 256.8 0.5 6.7e-76 255.2 0.5 2.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 KKK20296.1 - 1.5e-37 128.2 0.1 5.3e-37 126.4 0.1 2.0 2 0 0 2 2 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.25 KKK20296.1 - 2e-33 114.6 4.8 5.4e-16 58.7 0.7 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site PS-DH PF14765.6 KKK20296.1 - 7.7e-27 94.3 0.0 1.4e-26 93.4 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase HTH_51 PF18558.1 KKK20296.1 - 6.3e-25 86.9 0.1 6.4e-24 83.6 0.1 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain Acyl_transf_1 PF00698.21 KKK20296.1 - 5.5e-20 72.1 0.0 2.7e-19 69.8 0.0 2.0 2 0 0 2 2 2 1 Acyl transferase domain Methyltransf_12 PF08242.12 KKK20296.1 - 1e-18 67.9 0.0 3e-18 66.4 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Abhydrolase_3 PF07859.13 KKK20296.1 - 4e-14 53.0 0.0 8.9e-11 42.0 0.0 2.6 2 0 0 2 2 2 2 alpha/beta hydrolase fold Methyltransf_25 PF13649.6 KKK20296.1 - 2.6e-12 47.3 0.0 1.1e-11 45.2 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KKK20296.1 - 1.3e-11 44.6 0.0 3.5e-11 43.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KKK20296.1 - 6.6e-11 42.7 0.0 3.8e-10 40.3 0.0 2.4 2 0 0 2 2 1 1 Methyltransferase domain SAT PF16073.5 KKK20296.1 - 6.7e-10 39.1 5.1 1.4e-07 31.5 0.4 3.2 2 1 0 2 2 2 2 Starter unit:ACP transacylase in aflatoxin biosynthesis Peptidase_S9 PF00326.21 KKK20296.1 - 7.7e-10 38.6 0.0 3.5e-07 29.9 0.0 2.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family Methyltransf_31 PF13847.6 KKK20296.1 - 1.7e-09 37.6 0.0 8.9e-09 35.3 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 KKK20296.1 - 2.7e-09 37.5 0.1 1.4e-08 35.1 0.1 2.2 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension Abhydrolase_6 PF12697.7 KKK20296.1 - 4.3e-06 27.5 4.9 5.4e-05 23.9 1.5 2.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Thiolase_N PF00108.23 KKK20296.1 - 1.2e-05 24.8 0.2 2.5e-05 23.8 0.2 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain DLH PF01738.18 KKK20296.1 - 5.8e-05 22.7 0.0 0.0013 18.3 0.0 2.6 2 0 0 2 2 2 1 Dienelactone hydrolase family Methyltransf_33 PF10017.9 KKK20296.1 - 0.00031 20.0 0.0 0.0021 17.2 0.0 2.2 2 0 0 2 2 2 1 Histidine-specific methyltransferase, SAM-dependent Ubie_methyltran PF01209.18 KKK20296.1 - 0.00053 19.4 0.0 0.0013 18.1 0.0 1.6 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Hydrolase_4 PF12146.8 KKK20296.1 - 0.0006 19.2 0.1 0.007 15.7 0.0 2.7 3 0 0 3 3 3 1 Serine aminopeptidase, S33 Methyltransf_28 PF02636.17 KKK20296.1 - 0.0015 18.2 0.0 0.003 17.2 0.0 1.5 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_16 PF10294.9 KKK20296.1 - 0.007 16.1 0.0 0.018 14.8 0.0 1.6 1 0 0 1 1 1 1 Lysine methyltransferase COesterase PF00135.28 KKK20296.1 - 0.015 14.2 0.0 0.025 13.5 0.0 1.2 1 0 0 1 1 1 0 Carboxylesterase family Peptidase_S15 PF02129.18 KKK20296.1 - 0.018 14.6 0.0 0.14 11.7 0.0 2.3 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_2 PF02230.16 KKK20296.1 - 0.039 13.7 0.0 4.1 7.1 0.0 2.7 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase LIP PF03583.14 KKK20296.1 - 0.089 12.1 0.0 0.21 10.9 0.0 1.6 1 0 0 1 1 1 0 Secretory lipase Lactamase_B PF00753.27 KKK20297.1 - 1.2e-08 35.3 0.9 1.6e-07 31.5 0.9 2.2 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KKK20297.1 - 0.00085 18.9 0.1 0.0016 18.0 0.1 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain p450 PF00067.22 KKK20298.1 - 3.5e-55 187.6 0.0 1.5e-54 185.5 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 ketoacyl-synt PF00109.26 KKK20299.1 - 4.9e-63 213.1 0.0 1.1e-62 211.9 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 KKK20299.1 - 1e-60 204.7 1.1 2.5e-60 203.5 0.2 2.1 2 0 0 2 2 2 1 KR domain PS-DH PF14765.6 KKK20299.1 - 2.6e-53 181.2 0.0 7.3e-53 179.7 0.0 1.8 2 0 0 2 2 2 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 KKK20299.1 - 6.6e-50 170.4 0.1 2.1e-49 168.8 0.1 1.9 1 1 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KKK20299.1 - 1.9e-39 134.3 0.0 6.1e-39 132.7 0.0 2.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N_2 PF13602.6 KKK20299.1 - 2.7e-16 60.9 0.0 6.9e-15 56.3 0.0 3.3 3 0 0 3 3 3 1 Zinc-binding dehydrogenase KAsynt_C_assoc PF16197.5 KKK20299.1 - 1.8e-14 54.1 0.0 6.7e-14 52.3 0.0 2.0 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension adh_short PF00106.25 KKK20299.1 - 6.6e-14 51.8 2.0 4.9e-13 49.0 0.3 2.6 2 0 0 2 2 2 1 short chain dehydrogenase ADH_zinc_N PF00107.26 KKK20299.1 - 1.1e-12 48.1 0.0 5.3e-12 45.9 0.1 2.2 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.12 KKK20299.1 - 2e-12 47.7 0.0 3.2e-11 43.8 0.0 3.1 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KKK20299.1 - 9.1e-12 45.1 0.0 2.1e-11 44.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain adh_short_C2 PF13561.6 KKK20299.1 - 7.3e-08 32.2 0.6 3.3e-07 30.1 0.1 2.3 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Sacchrp_dh_NADP PF03435.18 KKK20299.1 - 7.9e-06 26.2 0.0 0.058 13.7 0.0 2.7 2 0 0 2 2 2 2 Saccharopine dehydrogenase NADP binding domain PP-binding PF00550.25 KKK20299.1 - 8e-06 26.1 1.4 1.3e-05 25.4 0.2 2.0 2 0 0 2 2 1 1 Phosphopantetheine attachment site Methyltransf_31 PF13847.6 KKK20299.1 - 2.3e-05 24.2 0.0 0.00011 22.0 0.0 2.2 2 1 0 2 2 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKK20299.1 - 3.3e-05 24.5 0.1 0.00051 20.7 0.0 3.1 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 KKK20299.1 - 5.1e-05 22.7 0.0 0.00013 21.4 0.0 1.6 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 KKK20299.1 - 5.5e-05 23.7 0.1 0.00058 20.5 0.0 2.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_16 PF10294.9 KKK20299.1 - 0.00049 19.9 0.0 0.0017 18.1 0.0 1.8 2 0 0 2 2 2 1 Lysine methyltransferase ADH_N PF08240.12 KKK20299.1 - 0.0015 18.4 0.2 0.0046 16.8 0.2 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain GDP_Man_Dehyd PF16363.5 KKK20299.1 - 0.045 13.1 0.0 0.076 12.4 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Thiolase_N PF00108.23 KKK20299.1 - 0.056 12.8 0.1 0.14 11.5 0.1 1.6 1 0 0 1 1 1 0 Thiolase, N-terminal domain Transferase PF02458.15 KKK20300.1 - 1.7e-17 63.2 0.0 1.1e-14 54.0 0.0 2.5 2 1 0 2 2 2 2 Transferase family GMC_oxred_N PF00732.19 KKK20301.1 - 2.1e-55 188.2 0.0 2.9e-55 187.7 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KKK20301.1 - 2.6e-32 112.3 0.0 6e-32 111.1 0.0 1.7 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_3 PF13738.6 KKK20301.1 - 3.9e-09 36.2 0.1 0.0018 17.6 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KKK20301.1 - 1.3e-05 24.5 1.7 0.0075 15.4 0.3 2.2 2 0 0 2 2 2 2 FAD binding domain Trp_halogenase PF04820.14 KKK20301.1 - 1.3e-05 24.3 0.2 2.2e-05 23.5 0.2 1.3 1 0 0 1 1 1 1 Tryptophan halogenase DAO PF01266.24 KKK20301.1 - 1.6e-05 24.7 0.5 0.00051 19.7 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KKK20301.1 - 0.0001 21.5 0.4 0.0013 17.9 0.2 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KKK20301.1 - 0.00015 21.1 0.1 0.00059 19.2 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KKK20301.1 - 0.00027 20.3 0.1 0.0019 17.5 0.0 2.0 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.6 KKK20301.1 - 0.00068 19.8 0.1 0.002 18.3 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KKK20301.1 - 0.019 14.9 0.1 0.047 13.7 0.1 1.7 1 0 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox PF00070.27 KKK20301.1 - 0.1 13.2 0.3 0.57 10.8 0.1 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KKK20301.1 - 0.13 11.0 0.1 0.21 10.2 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein TrkA_N PF02254.18 KKK20301.1 - 0.19 12.0 0.3 0.44 10.8 0.3 1.6 1 0 0 1 1 1 0 TrkA-N domain GPI-anchored PF10342.9 KKK20302.1 - 2.8e-24 85.7 0.1 2.8e-24 85.7 0.1 2.2 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Phosphoesterase PF04185.14 KKK20303.1 - 8.2e-23 81.2 6.4 2e-22 79.9 2.2 2.5 1 1 1 2 2 2 2 Phosphoesterase family YopD PF05844.12 KKK20303.1 - 0.13 11.2 0.1 0.25 10.3 0.1 1.3 1 0 0 1 1 1 0 YopD protein AA_permease_2 PF13520.6 KKK20304.1 - 1.6e-42 145.9 34.1 1.2e-23 83.7 8.9 2.1 1 1 1 2 2 2 2 Amino acid permease AA_permease PF00324.21 KKK20304.1 - 1.4e-12 46.9 38.8 2.3e-08 33.1 17.1 2.5 1 1 1 2 2 2 2 Amino acid permease SLC35F PF06027.12 KKK20305.1 - 5.1e-92 308.6 26.8 5.9e-92 308.4 26.8 1.0 1 0 0 1 1 1 1 Solute carrier family 35 CRT-like PF08627.10 KKK20305.1 - 2.5e-08 33.3 5.9 4.5e-08 32.4 5.9 1.5 1 0 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like EamA PF00892.20 KKK20305.1 - 5.3e-05 23.4 37.6 0.014 15.5 15.9 2.3 2 1 0 2 2 2 2 EamA-like transporter family p450 PF00067.22 KKK20306.1 - 2.7e-45 155.0 0.0 3.8e-45 154.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_2 PF00891.18 KKK20307.1 - 1.4e-21 76.8 0.0 2.6e-21 75.9 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase domain HTH_Crp_2 PF13545.6 KKK20307.1 - 0.19 11.8 0.0 0.39 10.7 0.0 1.5 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain Fungal_trans PF04082.18 KKK20308.1 - 1e-10 41.1 0.0 2e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK20308.1 - 5.5e-09 36.0 11.2 1e-08 35.1 11.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Myb_DNA-binding PF00249.31 KKK20309.1 - 8.8e-34 115.5 15.3 5e-12 45.8 3.5 3.3 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KKK20309.1 - 7e-27 93.5 8.6 4.7e-10 39.6 3.0 3.3 2 1 1 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 KKK20309.1 - 0.0011 18.8 1.5 0.11 12.4 0.0 2.6 3 0 0 3 3 3 1 Myb DNA-binding like SANT_DAMP1_like PF16282.5 KKK20309.1 - 0.032 14.4 1.4 2.7 8.3 0.1 2.5 1 1 1 2 2 2 0 SANT/Myb-like domain of DAMP1 SLIDE PF09111.10 KKK20309.1 - 0.057 13.4 0.1 3 7.9 0.0 2.6 1 1 1 2 2 2 0 SLIDE Rap1_C PF11626.8 KKK20309.1 - 0.33 11.1 5.2 0.66 10.1 1.1 2.9 2 1 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain MADF_DNA_bdg PF10545.9 KKK20309.1 - 0.8 10.1 9.4 11 6.4 1.4 3.3 3 0 0 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-binding PF00249.31 KKK20310.1 - 2.3e-34 117.3 11.9 3.6e-12 46.3 0.7 3.8 4 0 0 4 4 4 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KKK20310.1 - 6.4e-25 87.2 5.1 3.8e-08 33.5 0.1 3.3 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 KKK20310.1 - 0.00017 21.4 0.0 0.37 10.7 0.0 2.5 2 0 0 2 2 2 2 Myb DNA-binding like DUF3237 PF11578.8 KKK20310.1 - 0.14 12.0 0.1 2 8.2 0.1 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF3237) MADF_DNA_bdg PF10545.9 KKK20310.1 - 0.19 12.1 1.4 8.3 6.8 0.1 2.9 3 0 0 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like MFS_1 PF07690.16 KKK20311.1 - 5.9e-41 140.6 42.5 5.9e-41 140.6 42.5 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KKK20311.1 - 2.1e-14 52.9 14.0 3.6e-14 52.1 8.0 2.0 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) DUF3572 PF12096.8 KKK20311.1 - 0.13 12.5 0.1 19 5.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3572) SYF2 PF08231.12 KKK20347.1 - 1.2e-56 191.5 16.0 1.2e-56 191.5 16.0 2.0 2 0 0 2 2 2 1 SYF2 splicing factor Polysacc_deac_1 PF01522.21 KKK20348.1 - 2.7e-19 69.3 0.0 6.5e-19 68.0 0.0 1.6 1 0 0 1 1 1 1 Polysaccharide deacetylase Nitroreductase PF00881.24 KKK20348.1 - 3.5e-16 59.7 0.0 5.5e-16 59.1 0.0 1.3 1 0 0 1 1 1 1 Nitroreductase family Glyco_hydro_57 PF03065.15 KKK20348.1 - 2.4e-07 30.3 0.0 4.5e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 Creatininase PF02633.14 KKK20348.1 - 1.3e-06 28.1 0.1 3e-06 26.9 0.1 1.5 1 0 0 1 1 1 1 Creatinine amidohydrolase Cpn60_TCP1 PF00118.24 KKK20350.1 - 1.3e-146 489.1 9.9 1.6e-146 488.8 9.9 1.1 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Peptidase_M48 PF01435.18 KKK20350.1 - 8.1e-36 123.6 0.0 4.6e-34 117.9 0.0 2.4 2 0 0 2 2 2 1 Peptidase family M48 DUF2052 PF09747.9 KKK20350.1 - 0.006 16.7 2.3 0.011 15.9 2.3 1.3 1 0 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) Sigma70_ner PF04546.13 KKK20350.1 - 0.024 14.5 3.1 0.051 13.5 3.1 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region Ribosomal_60s PF00428.19 KKK20350.1 - 0.075 13.6 10.9 0.28 11.8 10.9 2.0 1 0 0 1 1 1 0 60s Acidic ribosomal protein RPN2_C PF18004.1 KKK20350.1 - 0.11 12.4 4.2 0.23 11.3 4.2 1.5 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain PPP4R2 PF09184.11 KKK20350.1 - 0.12 12.0 3.8 0.23 11.0 3.5 1.6 2 0 0 2 2 2 0 PPP4R2 RXT2_N PF08595.11 KKK20350.1 - 0.31 11.0 3.6 0.65 10.0 3.6 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal TetR_C_14 PF17754.1 KKK20350.1 - 0.58 10.1 4.2 1.2 9.1 1.3 2.5 2 0 0 2 2 2 0 MftR C-terminal domain DUF913 PF06025.12 KKK20350.1 - 0.76 8.7 2.6 0.94 8.4 1.0 1.9 3 0 0 3 3 3 0 Domain of Unknown Function (DUF913) Nop14 PF04147.12 KKK20350.1 - 1.1 7.3 8.3 1.7 6.8 8.3 1.1 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.12 KKK20350.1 - 1.2 8.4 10.9 1.9 7.8 10.9 1.2 1 0 0 1 1 1 0 NOA36 protein FAM176 PF14851.6 KKK20350.1 - 1.3 8.7 6.6 2.7 7.7 6.6 1.5 1 0 0 1 1 1 0 FAM176 family Pox_Ag35 PF03286.14 KKK20350.1 - 1.4 8.7 7.2 0.43 10.3 4.0 1.7 2 0 0 2 2 1 0 Pox virus Ag35 surface protein SURF2 PF05477.11 KKK20350.1 - 2.3 7.8 4.5 4.1 7.0 4.5 1.3 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) DNA_pol_phi PF04931.13 KKK20350.1 - 2.4 6.2 11.7 4.1 5.4 11.7 1.3 1 0 0 1 1 1 0 DNA polymerase phi DUF4746 PF15928.5 KKK20350.1 - 2.4 7.5 6.7 3.9 6.8 6.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Nop53 PF07767.11 KKK20350.1 - 2.5 7.4 10.1 4.2 6.7 10.1 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) CENP-B_dimeris PF09026.10 KKK20350.1 - 9.7 6.7 15.3 26 5.3 15.3 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Fungal_trans_2 PF11951.8 KKK20351.1 - 6.4e-77 258.9 0.1 1.6e-38 132.5 0.2 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK20351.1 - 1.4e-05 25.1 11.2 2.4e-05 24.4 11.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Njmu-R1 PF15053.6 KKK20351.1 - 0.13 11.3 0.5 5.5 6.0 0.0 2.1 2 0 0 2 2 2 0 Mjmu-R1-like protein family AAA PF00004.29 KKK20352.1 - 4.3e-06 27.2 0.0 1.5e-05 25.4 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) BCS1_N PF08740.11 KKK20352.1 - 0.00034 20.7 0.2 0.00047 20.2 0.2 1.2 1 0 0 1 1 1 1 BCS1 N terminal RuvB_N PF05496.12 KKK20352.1 - 0.0018 18.1 0.0 0.003 17.3 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KKK20352.1 - 0.0077 16.6 0.0 0.0099 16.3 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 KKK20352.1 - 0.011 15.4 0.0 0.016 14.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 KKK20352.1 - 0.013 15.5 0.0 0.021 14.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ATPase PF06745.13 KKK20352.1 - 0.016 14.6 0.0 0.023 14.1 0.0 1.2 1 0 0 1 1 1 0 KaiC Mg_chelatase PF01078.21 KKK20352.1 - 0.069 12.5 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_29 PF13555.6 KKK20352.1 - 0.094 12.5 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.6 KKK20352.1 - 0.13 12.8 0.0 0.2 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KKK20352.1 - 0.13 11.7 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 KKK20352.1 - 0.17 12.0 0.0 0.28 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 KKK20352.1 - 0.17 11.6 0.0 0.2 11.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KKK20352.1 - 0.2 11.9 0.3 0.39 11.0 0.1 1.5 2 0 0 2 2 1 0 AAA domain IstB_IS21 PF01695.17 KKK20352.1 - 0.2 11.4 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein Hormone_3 PF00159.18 KKK20352.1 - 0.87 9.7 3.8 3.9 7.6 0.5 2.6 2 0 0 2 2 2 0 Pancreatic hormone peptide Velvet PF11754.8 KKK20353.1 - 7e-58 196.5 0.0 1.5e-55 188.8 0.0 2.1 1 1 0 1 1 1 1 Velvet factor Ins_P5_2-kin PF06090.12 KKK20354.1 - 9.5e-46 156.7 0.0 1e-44 153.3 0.0 2.0 1 1 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase DUF4444 PF14563.6 KKK20354.1 - 0.025 14.3 0.0 0.05 13.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4444) Thiamine_BP PF01910.17 KKK20355.1 - 1.9e-11 43.7 0.1 5.6e-10 39.0 0.0 2.1 2 0 0 2 2 2 2 Thiamine-binding protein YEATS PF03366.16 KKK20356.1 - 8.3e-37 125.0 1.8 1.3e-36 124.4 1.8 1.3 1 0 0 1 1 1 1 YEATS family M16C_assoc PF08367.11 KKK20356.1 - 0.05 12.7 2.8 0.072 12.2 2.8 1.2 1 0 0 1 1 1 0 Peptidase M16C associated DUF334 PF03904.13 KKK20356.1 - 0.28 10.7 1.4 0.56 9.7 1.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF334) NAD_binding_10 PF13460.6 KKK20357.1 - 5.1e-06 26.5 0.0 4.2e-05 23.5 0.0 2.3 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KKK20357.1 - 2.2e-05 24.0 0.0 4.5e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KKK20357.1 - 6.2e-05 22.1 0.0 0.00012 21.2 0.0 1.5 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 KKK20357.1 - 0.003 17.0 0.0 0.0051 16.3 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.17 KKK20357.1 - 0.045 12.8 0.0 0.21 10.7 0.0 1.9 2 0 0 2 2 2 0 RmlD substrate binding domain KR PF08659.10 KKK20357.1 - 0.045 13.7 0.0 0.078 12.9 0.0 1.3 1 0 0 1 1 1 0 KR domain NAD_binding_4 PF07993.12 KKK20357.1 - 0.07 12.3 0.0 1.3 8.1 0.0 2.3 2 0 0 2 2 2 0 Male sterility protein SPX PF03105.19 KKK20358.1 - 0.36 10.7 5.1 1.1 9.1 1.9 2.1 2 0 0 2 2 2 0 SPX domain gag_pre-integrs PF13976.6 KKK20360.1 - 0.13 12.2 0.1 0.3 11.0 0.1 1.5 1 0 0 1 1 1 0 GAG-pre-integrase domain COX7a PF02238.15 KKK20361.1 - 9.5e-23 80.4 4.1 1.2e-22 80.0 4.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VII Aminotran_5 PF00266.19 KKK20362.1 - 7.8e-07 28.4 0.0 2.7e-06 26.6 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 KKK20362.1 - 0.0034 16.7 0.0 0.0048 16.2 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family IDO PF01231.18 KKK20363.1 - 1.8e-155 518.0 0.0 2e-155 517.8 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase Fungal_trans PF04082.18 KKK20367.1 - 1.5e-25 89.7 0.0 2.4e-25 89.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK20367.1 - 8.6e-09 35.4 12.6 1.3e-08 34.8 12.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 KKK20368.1 - 7.3e-37 127.1 15.1 7.1e-29 100.8 0.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KKK20368.1 - 5.2e-10 38.8 4.8 1.1e-09 37.7 4.8 1.5 1 0 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 KKK20368.1 - 0.0085 14.6 0.4 0.013 14.0 0.4 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Adenylsucc_synt PF00709.21 KKK20369.1 - 4.4e-165 549.7 0.0 5e-165 549.5 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase KHA PF11834.8 KKK20369.1 - 0.053 13.6 0.0 0.13 12.3 0.0 1.7 1 0 0 1 1 1 0 KHA, dimerisation domain of potassium ion channel DnaJ PF00226.31 KKK20370.1 - 2.8e-22 78.6 0.3 5.6e-22 77.6 0.3 1.6 1 0 0 1 1 1 1 DnaJ domain ADH_zinc_N PF00107.26 KKK20371.1 - 3.3e-21 75.6 0.0 5.1e-21 75.0 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 KKK20371.1 - 4.1e-18 65.2 0.0 6.9e-18 64.5 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 KKK20371.1 - 1.6e-07 32.4 0.0 4e-07 31.2 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase DEAD PF00270.29 KKK20372.1 - 2.9e-45 154.2 0.0 6e-45 153.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KKK20372.1 - 6e-20 71.6 0.1 1.9e-18 66.8 0.0 3.2 3 1 1 4 4 4 1 Helicase conserved C-terminal domain ResIII PF04851.15 KKK20372.1 - 3.9e-05 23.7 0.0 0.00014 22.0 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KKK20372.1 - 0.0054 16.0 0.0 0.0092 15.2 0.0 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase AAA_22 PF13401.6 KKK20372.1 - 0.021 15.1 0.5 0.15 12.3 0.0 2.6 3 1 0 3 3 3 0 AAA domain SecA_DEAD PF07517.14 KKK20372.1 - 0.11 11.8 0.0 0.41 9.9 0.0 1.9 2 0 0 2 2 2 0 SecA DEAD-like domain HEAT_EZ PF13513.6 KKK20373.1 - 5.6e-14 52.3 1.9 2.3e-10 40.7 0.2 5.3 4 2 2 6 6 6 2 HEAT-like repeat HEAT PF02985.22 KKK20373.1 - 1e-12 47.1 15.3 0.00014 21.8 0.2 8.8 9 1 0 9 9 9 2 HEAT repeat IBN_N PF03810.19 KKK20373.1 - 1.6e-09 37.6 2.4 1.6e-08 34.3 0.2 3.5 4 0 0 4 4 4 1 Importin-beta N-terminal domain HEAT_2 PF13646.6 KKK20373.1 - 9.8e-08 32.3 8.7 0.00058 20.2 0.6 6.2 3 2 4 7 7 7 4 HEAT repeats CLASP_N PF12348.8 KKK20373.1 - 2.1e-05 24.2 2.5 1.6 8.2 0.0 5.2 3 1 1 5 5 5 2 CLASP N terminal HEAT_PBS PF03130.16 KKK20373.1 - 0.0004 20.8 0.0 8 7.5 0.0 5.3 5 0 0 5 5 5 1 PBS lyase HEAT-like repeat Ecm29 PF13001.7 KKK20373.1 - 0.0015 17.3 0.4 0.74 8.4 0.0 3.6 3 1 1 4 4 4 2 Proteasome stabiliser Cnd1 PF12717.7 KKK20373.1 - 0.0017 18.4 0.7 0.02 15.0 0.0 3.0 2 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 Arm PF00514.23 KKK20373.1 - 0.01 15.8 1.9 5.9 7.1 0.0 3.6 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat Dopey_N PF04118.14 KKK20373.1 - 0.029 13.5 0.4 0.13 11.3 0.1 2.2 3 0 0 3 3 3 0 Dopey, N-terminal Ribosomal_S8 PF00410.19 KKK20374.1 - 2.6e-15 56.5 0.0 4.6e-15 55.7 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S8 His_Phos_1 PF00300.22 KKK20374.1 - 1.7e-12 47.4 0.0 4.1e-07 29.9 0.0 2.3 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) ANAPC4 PF12896.7 KKK20376.1 - 2e-68 229.9 2.4 2.8e-68 229.4 2.4 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 ANAPC4_WD40 PF12894.7 KKK20376.1 - 3.4e-32 110.6 0.0 3.2e-31 107.5 0.0 2.6 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain HpaP PF09483.10 KKK20376.1 - 0.0063 16.7 0.8 0.015 15.6 0.8 1.6 1 0 0 1 1 1 1 Type III secretion protein (HpaP) Tudor_3 PF18115.1 KKK20376.1 - 0.12 12.3 0.2 10 6.1 0.0 3.2 3 0 0 3 3 3 0 DNA repair protein Crb2 Tudor domain Fungal_trans_2 PF11951.8 KKK20377.1 - 0.0013 17.6 6.0 0.032 13.1 1.1 2.7 2 1 0 2 2 2 2 Fungal specific transcription factor domain VWA_2 PF13519.6 KKK20378.1 - 0.0034 18.0 0.0 0.0074 16.9 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 KKK20378.1 - 0.014 15.7 0.0 3 8.1 0.0 2.1 2 0 0 2 2 2 0 von Willebrand factor type A domain V-SNARE PF05008.15 KKK20379.1 - 0.37 11.2 2.5 0.87 10.0 2.5 1.7 1 0 0 1 1 1 0 Vesicle transport v-SNARE protein N-terminus Cu-oxidase_3 PF07732.15 KKK20380.1 - 1.3e-35 122.0 0.1 1.2e-34 118.8 0.0 2.6 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 KKK20380.1 - 1.4e-33 115.6 0.3 1.6e-26 92.7 0.0 3.5 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.22 KKK20380.1 - 9.5e-16 58.3 0.0 1.7e-14 54.2 0.0 2.9 3 1 0 3 3 3 1 Multicopper oxidase Choline_kinase PF01633.20 KKK20380.1 - 0.18 11.4 0.0 0.29 10.7 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase HLH PF00010.26 KKK20381.1 - 1.8e-08 34.2 0.0 3.6e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain GFA PF04828.14 KKK20382.1 - 0.0041 17.4 0.6 0.0079 16.5 0.0 1.9 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme CybS PF05328.12 KKK20383.1 - 1.3e-53 180.2 0.0 1.7e-53 179.9 0.0 1.1 1 0 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit Maf PF02545.14 KKK20384.1 - 1.3e-47 161.8 0.1 1.5e-47 161.5 0.1 1.0 1 0 0 1 1 1 1 Maf-like protein UL42 PF17638.2 KKK20384.1 - 0.053 13.5 3.6 0.097 12.6 3.6 1.4 1 0 0 1 1 1 0 HCMV UL42 NOA36 PF06524.12 KKK20384.1 - 0.15 11.3 3.2 0.18 11.1 3.2 1.1 1 0 0 1 1 1 0 NOA36 protein p450 PF00067.22 KKK20398.1 - 4.1e-22 78.6 0.0 7.7e-22 77.7 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 Ribosomal_L1 PF00687.21 KKK20399.1 - 8.8e-16 58.3 0.4 9.7e-16 58.1 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family DUF3671 PF12420.8 KKK20399.1 - 0.063 13.4 0.9 0.067 13.3 0.9 1.2 1 1 0 1 1 1 0 Protein of unknown function FMN_red PF03358.15 KKK20400.1 - 6.1e-09 35.8 0.0 7.7e-09 35.5 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 KKK20400.1 - 5.2e-07 29.6 0.0 6.7e-07 29.2 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_1 PF00258.25 KKK20400.1 - 0.00016 21.9 0.1 0.0064 16.7 0.0 2.2 1 1 0 1 1 1 1 Flavodoxin Flavodoxin_5 PF12724.7 KKK20400.1 - 0.021 15.0 0.0 0.037 14.3 0.0 1.4 1 0 0 1 1 1 0 Flavodoxin domain DUF3752 PF12572.8 KKK20401.1 - 2.2e-45 154.9 12.3 2.2e-45 154.9 12.3 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3752) DUF4337 PF14235.6 KKK20401.1 - 0.15 12.1 2.9 0.29 11.2 2.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) NPL4 PF05021.15 KKK20402.1 - 4.8e-135 449.8 0.0 5.9e-135 449.5 0.0 1.1 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.15 KKK20402.1 - 2e-70 235.6 0.1 3.2e-70 234.9 0.1 1.3 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region DUF2080 PF09853.9 KKK20402.1 - 0.012 15.4 0.0 0.026 14.2 0.0 1.6 1 0 0 1 1 1 0 Putative transposon-encoded protein (DUF2080) UN_NPL4 PF11543.8 KKK20402.1 - 0.021 15.3 0.0 0.2 12.2 0.0 2.3 1 1 0 1 1 1 0 Nuclear pore localisation protein NPL4 DUF2417 PF10329.9 KKK20403.1 - 2.7e-83 279.0 0.2 3.8e-83 278.5 0.2 1.2 1 0 0 1 1 1 1 Region of unknown function (DUF2417) Abhydrolase_1 PF00561.20 KKK20403.1 - 0.024 14.3 0.0 0.04 13.6 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold zf-CCCH PF00642.24 KKK20404.1 - 1.8e-19 69.2 29.3 1.4e-06 28.0 1.1 5.2 5 0 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KKK20404.1 - 1.2e-14 53.7 28.2 0.00019 21.4 1.7 5.1 5 0 0 5 5 5 4 Zinc finger domain Torus PF16131.5 KKK20404.1 - 2.4e-12 47.5 24.1 1e-05 26.2 0.8 5.2 1 1 4 5 5 5 5 Torus domain zf-CCCH_4 PF18044.1 KKK20404.1 - 2.3e-05 24.0 0.8 2.3e-05 24.0 0.8 4.8 5 0 0 5 5 5 2 CCCH-type zinc finger zf-C3H1 PF10650.9 KKK20404.1 - 0.001 18.7 5.7 0.13 12.1 0.0 3.8 4 0 0 4 4 4 2 Putative zinc-finger domain Atrophin-1 PF03154.15 KKK20404.1 - 1.7 6.8 6.6 0.62 8.3 4.4 1.3 2 0 0 2 2 2 0 Atrophin-1 family Abhydrolase_6 PF12697.7 KKK20405.1 - 7.3e-23 82.3 1.4 1.1e-22 81.8 1.4 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KKK20405.1 - 2.2e-06 27.5 0.1 8.8e-06 25.5 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KKK20405.1 - 0.0047 16.2 0.1 0.0087 15.3 0.0 1.6 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Lipase_3 PF01764.25 KKK20405.1 - 0.062 13.2 0.0 0.48 10.3 0.0 2.0 2 0 0 2 2 2 0 Lipase (class 3) Adeno_PIX PF03955.14 KKK20405.1 - 0.11 12.7 0.0 0.24 11.6 0.0 1.6 1 0 0 1 1 1 0 Adenovirus hexon-associated protein (IX) Abhydrolase_5 PF12695.7 KKK20405.1 - 0.14 11.9 0.0 0.23 11.2 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family WD40 PF00400.32 KKK20406.1 - 4.6e-47 157.0 24.1 5.8e-09 36.4 0.4 6.9 6 1 0 6 6 6 6 WD domain, G-beta repeat TFIID_NTD2 PF04494.15 KKK20406.1 - 2.7e-38 131.1 0.0 3.9e-38 130.6 0.0 1.2 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit, NTD2 domain ANAPC4_WD40 PF12894.7 KKK20406.1 - 4.8e-13 49.2 0.3 0.015 15.6 0.0 5.2 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain LisH PF08513.11 KKK20406.1 - 4.8e-07 29.5 0.0 1.1e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 LisH Nup160 PF11715.8 KKK20406.1 - 0.021 13.5 6.2 0.046 12.4 0.1 3.1 3 1 0 3 3 3 0 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 KKK20406.1 - 0.19 10.4 0.0 3.6 6.2 0.0 2.7 2 1 0 2 2 2 0 Nup133 N terminal like Macoilin PF09726.9 KKK20408.1 - 4.5 5.7 7.4 4.3 5.8 7.4 1.1 1 0 0 1 1 1 0 Macoilin family F_actin_cap_B PF01115.17 KKK20409.1 - 4.5e-88 294.9 0.0 4.7e-75 252.3 0.0 2.2 1 1 1 2 2 2 2 F-actin capping protein, beta subunit ResIII PF04851.15 KKK20409.1 - 5e-22 78.7 0.0 9.8e-22 77.7 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KKK20409.1 - 8.5e-20 71.2 0.0 3e-19 69.4 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KKK20409.1 - 3.3e-15 56.3 0.0 7.8e-15 55.1 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 KKK20409.1 - 0.0021 17.8 0.0 0.0039 16.9 0.0 1.3 1 0 0 1 1 1 1 SWI2/SNF2 ATPase UIM PF02809.20 KKK20409.1 - 0.016 15.1 0.4 0.047 13.6 0.4 1.9 1 0 0 1 1 1 0 Ubiquitin interaction motif AAA_22 PF13401.6 KKK20409.1 - 0.026 14.8 0.0 0.069 13.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain Hira PF07569.11 KKK20410.1 - 0.0036 17.1 0.1 22 4.7 0.0 3.3 3 0 0 3 3 3 3 TUP1-like enhancer of split HD PF01966.22 KKK20411.1 - 1.9e-06 28.1 1.1 6.3e-06 26.4 0.2 2.0 2 0 0 2 2 2 1 HD domain Med11 PF10280.9 KKK20412.1 - 2.8e-43 147.7 0.2 3.5e-43 147.4 0.2 1.1 1 0 0 1 1 1 1 Mediator complex protein Med29 PF11568.8 KKK20412.1 - 0.016 15.5 0.0 0.025 14.8 0.0 1.5 1 0 0 1 1 1 0 Mediator complex subunit 29 Cep57_MT_bd PF06657.13 KKK20412.1 - 0.1 13.0 0.9 0.5 10.8 0.1 2.2 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 DUF4404 PF14357.6 KKK20412.1 - 0.46 11.2 2.6 24 5.7 0.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) DUF3224 PF11528.8 KKK20436.1 - 8.9e-24 83.7 0.1 1.1e-23 83.4 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3224) Goodbye PF17109.5 KKK20439.1 - 1.5e-38 132.0 1.5 7.6e-38 129.7 0.0 2.9 3 0 0 3 3 3 1 fungal STAND N-terminal Goodbye domain TPR_12 PF13424.6 KKK20439.1 - 7.3e-07 29.4 0.3 0.47 10.8 0.1 4.5 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 KKK20439.1 - 1.8e-05 24.6 1.0 0.19 12.0 0.0 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat NACHT PF05729.12 KKK20439.1 - 5.3e-05 23.2 0.0 0.0004 20.4 0.0 2.4 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 KKK20439.1 - 7.1e-05 23.2 0.0 0.00049 20.5 0.0 2.5 1 0 0 1 1 1 1 AAA ATPase domain TPR_2 PF07719.17 KKK20439.1 - 0.00026 20.9 9.2 0.0026 17.7 0.2 5.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 KKK20439.1 - 0.00034 21.1 3.2 0.013 16.0 0.1 4.2 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_10 PF13374.6 KKK20439.1 - 0.00038 20.2 7.1 0.34 10.8 0.0 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 KKK20439.1 - 0.0013 18.6 0.7 0.17 12.0 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat RPN7 PF10602.9 KKK20439.1 - 0.0033 17.1 1.0 1.2 8.9 0.3 3.2 2 0 0 2 2 2 1 26S proteasome subunit RPN7 DUF2075 PF09848.9 KKK20439.1 - 0.004 16.4 0.3 0.097 11.9 0.0 2.6 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) TPR_1 PF00515.28 KKK20439.1 - 0.0079 16.0 5.5 0.024 14.5 0.1 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 KKK20439.1 - 0.014 16.1 6.7 0.088 13.7 0.1 4.9 3 1 1 4 4 4 0 Tetratricopeptide repeat AAA_22 PF13401.6 KKK20439.1 - 0.015 15.6 0.0 0.14 12.4 0.0 2.8 2 1 0 2 2 2 0 AAA domain DUF2786 PF10979.8 KKK20439.1 - 0.52 10.3 3.0 0.36 10.8 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2786) Muted PF14942.6 KKK20439.1 - 5.2 7.4 9.6 4.2 7.7 1.7 3.2 3 0 0 3 3 3 0 Organelle biogenesis, Muted-like protein AA_permease PF00324.21 KKK20440.1 - 3e-109 365.8 37.4 3.7e-109 365.5 37.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KKK20440.1 - 1.2e-36 126.5 41.0 1.4e-36 126.2 41.0 1.1 1 0 0 1 1 1 1 Amino acid permease Tweety PF04906.13 KKK20440.1 - 0.75 8.4 3.9 1.3 7.6 3.9 1.3 1 0 0 1 1 1 0 Tweety MFS_1 PF07690.16 KKK20441.1 - 7.6e-43 146.8 52.0 7.6e-43 146.8 52.0 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily MFS_1 PF07690.16 KKK20442.1 - 1.7e-52 178.5 26.7 1.7e-52 178.5 26.7 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KKK20442.1 - 2.6e-11 43.1 10.6 2.6e-11 43.1 10.6 2.9 3 0 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 KKK20442.1 - 3.2e-06 25.8 3.4 7.3e-06 24.7 3.4 1.5 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_5 PF05631.14 KKK20442.1 - 0.00044 19.3 5.6 0.00086 18.3 2.9 2.1 2 0 0 2 2 2 1 Sugar-tranasporters, 12 TM CPP1-like PF11833.8 KKK20442.1 - 0.36 10.4 3.8 1.4 8.6 3.8 2.0 1 0 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Fungal_trans PF04082.18 KKK20443.1 - 2e-10 40.2 0.1 3.5e-10 39.4 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK20443.1 - 4.6e-07 29.8 10.1 4.6e-07 29.8 10.1 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 KKK20444.1 - 1.1e-23 83.7 18.7 2e-23 82.9 18.7 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1180 PF06679.12 KKK20444.1 - 0.013 15.9 0.2 0.022 15.2 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) TMEM132D_C PF15706.5 KKK20444.1 - 0.074 12.8 1.4 0.12 12.2 0.0 1.9 2 0 0 2 2 2 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term YoqO PF14037.6 KKK20444.1 - 0.076 13.6 0.7 0.2 12.2 0.2 1.9 2 0 0 2 2 2 0 YoqO-like protein Peptidase_M10 PF00413.24 KKK20444.1 - 0.12 12.2 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Matrixin DUF1772 PF08592.11 KKK20444.1 - 0.89 9.9 10.8 1.4 9.2 4.1 3.6 2 1 0 4 4 4 0 Domain of unknown function (DUF1772) Fungal_trans PF04082.18 KKK20445.1 - 2.4e-11 43.2 0.1 3.8e-11 42.5 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK20445.1 - 7.6e-08 32.4 11.2 1.7e-07 31.2 11.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dyp_perox PF04261.12 KKK20446.1 - 1.9e-87 293.3 0.0 2.2e-87 293.1 0.0 1.0 1 0 0 1 1 1 1 Dyp-type peroxidase family adh_short PF00106.25 KKK20448.1 - 3.4e-25 88.6 0.0 1.3e-23 83.5 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KKK20448.1 - 2.2e-11 44.0 0.0 4.6e-11 43.0 0.0 1.5 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 KKK20448.1 - 2.3e-11 43.7 0.0 3e-10 40.0 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.15 KKK20448.1 - 1.9e-05 24.0 0.0 2.8e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 KKK20448.1 - 7.1e-05 22.4 0.0 0.00077 19.0 0.0 2.4 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 KKK20448.1 - 0.03 14.4 0.1 0.07 13.2 0.1 1.6 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 KKK20448.1 - 0.053 13.8 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain TLP-20 PF06088.11 KKK20449.1 - 0.16 11.9 4.6 0.2 11.6 4.6 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Zip PF02535.22 KKK20449.1 - 6 6.0 5.3 5.9 6.0 5.3 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter Fungal_trans_2 PF11951.8 KKK20450.1 - 0.0087 14.9 1.1 0.096 11.5 0.4 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain DUF3112 PF11309.8 KKK20452.1 - 1.2e-10 41.3 2.6 3.4e-05 23.4 0.0 3.0 2 1 1 3 3 3 2 Protein of unknown function (DUF3112) YwiC PF14256.6 KKK20452.1 - 0.81 10.0 8.8 0.48 10.8 2.0 2.7 2 1 0 2 2 2 0 YwiC-like protein MerC PF03203.14 KKK20452.1 - 1.5 9.3 8.3 12 6.4 0.7 2.5 1 1 1 2 2 2 0 MerC mercury resistance protein Zn_clus PF00172.18 KKK20453.1 - 3.4e-05 23.9 12.5 5.9e-05 23.1 12.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DNA_ligase_A_N PF04675.14 KKK20453.1 - 0.15 12.4 0.0 0.36 11.1 0.0 1.6 1 0 0 1 1 1 0 DNA ligase N terminus Clr5 PF14420.6 KKK20454.1 - 9e-13 48.2 0.6 2.1e-12 47.0 0.6 1.7 1 0 0 1 1 1 1 Clr5 domain TauD PF02668.16 KKK20455.1 - 1.9e-51 175.4 0.0 2.5e-51 175.0 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Aldo_ket_red PF00248.21 KKK20456.1 - 6.7e-59 199.5 0.0 8.5e-59 199.1 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family FGGY_C PF02782.16 KKK20471.1 - 1.3e-74 250.2 0.9 2.5e-74 249.3 0.9 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 KKK20471.1 - 4.6e-60 203.2 0.0 6.1e-60 202.8 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.20 KKK20471.1 - 0.0012 18.4 0.6 0.033 13.7 0.0 2.2 2 0 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family DUF3429 PF11911.8 KKK20472.1 - 8.2e-44 149.4 12.7 1.2e-43 148.9 12.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) SHR-BD PF06650.12 KKK20473.1 - 1.1e-98 330.0 0.0 1.1e-97 326.7 0.0 2.6 2 1 0 2 2 2 1 SHR-binding domain of vacuolar-sorting associated protein 13 VPS13_mid_rpt PF16910.5 KKK20473.1 - 8.1e-90 300.4 9.1 4.9e-87 291.3 0.5 4.5 4 0 0 4 4 4 2 Repeating coiled region of VPS13 VPS13 PF16908.5 KKK20473.1 - 1.5e-79 267.1 0.6 6.2e-78 261.8 0.0 3.7 5 0 0 5 5 5 1 Vacuolar sorting-associated protein 13, N-terminal VPS13_C PF16909.5 KKK20473.1 - 2.6e-73 245.6 2.8 1.2e-67 227.2 0.2 2.6 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal Chorein_N PF12624.7 KKK20473.1 - 2.3e-40 137.4 0.0 6e-40 136.0 0.0 1.8 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 ATG_C PF09333.11 KKK20473.1 - 2.5e-06 27.8 1.2 5.1e-06 26.7 0.0 2.2 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain MFS_1 PF07690.16 KKK20474.1 - 1.2e-20 73.8 38.0 1.8e-15 56.8 21.7 2.8 2 1 1 3 3 3 2 Major Facilitator Superfamily DUF2749 PF10907.8 KKK20474.1 - 0.1 12.8 0.0 0.35 11.1 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2749) GCFC PF07842.12 KKK20475.1 - 2.1e-89 299.8 3.0 2.1e-89 299.8 3.0 1.6 2 0 0 2 2 2 1 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.23 KKK20475.1 - 3.7e-17 61.9 1.0 8.7e-17 60.7 1.0 1.7 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 KKK20475.1 - 9.5e-09 35.2 0.5 9.5e-09 35.2 0.5 2.3 2 0 0 2 2 2 1 G-patch domain DUF3425 PF11905.8 KKK20475.1 - 0.033 14.2 0.0 0.1 12.6 0.0 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF3425) DUF5082 PF16888.5 KKK20475.1 - 0.08 13.2 1.8 0.57 10.5 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) PilX PF13681.6 KKK20475.1 - 0.098 13.0 0.0 0.83 10.1 0.0 2.5 3 0 0 3 3 3 0 Type IV pilus assembly protein PilX C-term KRTAP PF11759.8 KKK20475.1 - 2.4 8.8 6.1 4.7 7.8 6.1 1.4 1 0 0 1 1 1 0 Keratin-associated matrix FUSC PF04632.12 KKK20475.1 - 8.8 4.7 6.4 14 4.1 6.4 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Sod_Fe_C PF02777.18 KKK20476.1 - 1.4e-37 128.0 1.5 1.8e-37 127.6 0.4 1.6 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 KKK20476.1 - 4.8e-17 62.2 6.6 9e-17 61.3 6.6 1.5 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain F-box PF00646.33 KKK20477.1 - 0.014 15.3 0.0 0.033 14.1 0.0 1.7 1 0 0 1 1 1 0 F-box domain Cnn_1N PF07989.11 KKK20478.1 - 1.5e-09 37.9 10.3 3.5e-09 36.7 10.3 1.7 1 0 0 1 1 1 1 Centrosomin N-terminal motif 1 AAA_23 PF13476.6 KKK20478.1 - 0.025 15.1 11.4 0.052 14.1 11.2 1.5 2 0 0 2 2 2 0 AAA domain YabA PF06156.13 KKK20478.1 - 0.25 12.0 7.5 0.97 10.1 7.4 2.1 2 1 0 2 2 2 0 Initiation control protein YabA FlaC_arch PF05377.11 KKK20478.1 - 1.5 9.2 6.2 2.1 8.8 4.3 2.2 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF3584 PF12128.8 KKK20478.1 - 4 4.8 17.2 5.6 4.4 17.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) PKcGMP_CC PF16808.5 KKK20478.1 - 5.9 6.8 10.4 0.71 9.8 5.6 2.0 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Sld5 PF05916.11 KKK20479.1 - 1.2e-20 74.0 0.0 1.5e-20 73.7 0.0 1.1 1 0 0 1 1 1 1 GINS complex protein Peptidase_M41 PF01434.18 KKK20480.1 - 1.7e-56 191.1 0.5 3.2e-56 190.2 0.2 1.6 2 0 0 2 2 2 1 Peptidase family M41 AAA PF00004.29 KKK20480.1 - 1.6e-42 145.1 0.0 5.1e-42 143.4 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KKK20480.1 - 4.1e-11 42.5 0.0 1e-10 41.3 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 KKK20480.1 - 1.2e-05 25.3 0.0 4.6e-05 23.4 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 KKK20480.1 - 6.9e-05 22.2 1.6 0.00015 21.1 0.0 2.2 3 0 0 3 3 3 1 TIP49 P-loop domain AAA_22 PF13401.6 KKK20480.1 - 7.6e-05 23.0 0.4 0.025 14.9 0.3 3.2 2 2 0 2 2 2 1 AAA domain RuvB_N PF05496.12 KKK20480.1 - 0.00023 20.9 0.0 0.00068 19.4 0.0 1.8 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KKK20480.1 - 0.00042 20.7 6.2 0.00043 20.7 1.1 3.3 2 2 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.6 KKK20480.1 - 0.0032 17.6 0.2 0.013 15.6 0.0 2.2 3 0 0 3 3 1 1 AAA domain IstB_IS21 PF01695.17 KKK20480.1 - 0.012 15.4 0.0 0.022 14.5 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_2 PF07724.14 KKK20480.1 - 0.016 15.3 0.0 0.051 13.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_25 PF13481.6 KKK20480.1 - 0.022 14.3 1.5 0.79 9.3 0.3 2.5 1 1 1 2 2 2 0 AAA domain Mg_chelatase PF01078.21 KKK20480.1 - 0.025 13.9 0.2 0.051 13.0 0.2 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 KKK20480.1 - 0.027 15.0 0.0 0.09 13.3 0.0 2.0 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KKK20480.1 - 0.054 13.4 0.4 1.9 8.4 0.1 2.6 2 0 0 2 2 2 0 NACHT domain ATPase PF06745.13 KKK20480.1 - 0.064 12.6 0.4 1.5 8.1 0.0 2.6 3 0 0 3 3 3 0 KaiC DUF815 PF05673.13 KKK20480.1 - 0.072 12.2 0.0 0.16 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_17 PF13207.6 KKK20480.1 - 0.076 13.4 0.0 0.2 12.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KKK20480.1 - 0.08 13.2 0.2 0.2 11.9 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_7 PF12775.7 KKK20480.1 - 0.12 11.8 0.1 0.4 10.2 0.1 1.8 1 1 0 1 1 1 0 P-loop containing dynein motor region Zeta_toxin PF06414.12 KKK20480.1 - 0.23 10.7 2.4 0.83 8.9 0.5 2.5 2 1 1 3 3 3 0 Zeta toxin REPA_OB_2 PF16900.5 KKK20481.1 - 0.1 12.5 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Replication protein A OB domain NTP_transferase PF00483.23 KKK20482.1 - 3.7e-52 177.4 0.0 6.9e-52 176.5 0.0 1.4 2 0 0 2 2 2 1 Nucleotidyl transferase Hexapep PF00132.24 KKK20482.1 - 2.9e-14 52.1 9.0 8e-11 41.2 3.0 3.8 1 1 1 2 2 2 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 KKK20482.1 - 3.2e-10 40.6 0.0 4.8e-10 40.0 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.6 KKK20482.1 - 1.9e-06 27.5 1.5 1.9e-06 27.5 1.5 3.0 3 0 0 3 3 3 1 Hexapeptide repeat of succinyl-transferase DUF4954 PF16314.5 KKK20482.1 - 0.012 13.8 0.2 0.017 13.3 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4954) IspD PF01128.19 KKK20482.1 - 0.19 11.5 0.0 0.3 10.8 0.0 1.3 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Pkinase PF00069.25 KKK20484.1 - 2.4e-72 243.5 0.0 3.4e-72 243.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK20484.1 - 2.7e-36 125.2 0.0 4.2e-36 124.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KKK20484.1 - 6.5e-06 25.7 0.0 1.3e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like SPX PF03105.19 KKK20484.1 - 3.4 7.5 15.0 6.3 6.6 15.0 1.5 1 0 0 1 1 1 0 SPX domain zf-Tim10_DDP PF02953.15 KKK20485.1 - 5.7e-22 77.1 0.8 8e-22 76.7 0.8 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger PALB2_WD40 PF16756.5 KKK20485.1 - 0.036 13.0 0.5 0.046 12.7 0.5 1.1 1 0 0 1 1 1 0 Partner and localizer of BRCA2 WD40 domain DNA_pol3_delta2 PF13177.6 KKK20486.1 - 1.2e-10 41.4 0.1 2.2e-10 40.6 0.1 1.5 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.29 KKK20486.1 - 8.8e-06 26.2 0.1 2.1e-05 25.0 0.1 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KKK20486.1 - 2.8e-05 24.4 0.3 0.00016 21.9 0.2 2.2 1 1 1 2 2 2 1 AAA domain Rep_fac_C PF08542.11 KKK20486.1 - 0.00028 21.3 0.1 0.001 19.4 0.0 2.0 2 0 0 2 2 2 1 Replication factor C C-terminal domain AAA_24 PF13479.6 KKK20486.1 - 0.0034 17.1 0.4 0.0085 15.8 0.4 1.6 1 1 0 1 1 1 1 AAA domain Rad17 PF03215.15 KKK20486.1 - 0.004 17.1 0.0 0.019 14.9 0.0 1.9 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_16 PF13191.6 KKK20486.1 - 0.0053 17.2 1.1 0.096 13.1 0.4 2.8 2 1 0 2 2 2 1 AAA ATPase domain ABC_tran PF00005.27 KKK20486.1 - 0.041 14.4 0.1 0.086 13.4 0.1 1.6 1 1 0 1 1 1 0 ABC transporter DNA_pol3_delta PF06144.13 KKK20486.1 - 0.049 13.4 0.1 0.095 12.5 0.1 1.4 1 0 0 1 1 1 0 DNA polymerase III, delta subunit Ribosomal_L16 PF00252.18 KKK20487.1 - 3.1e-32 111.3 0.1 3.9e-32 111.0 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e RFC1 PF08519.12 KKK20488.1 - 1.3e-61 207.4 0.0 3e-60 203.0 0.0 2.4 2 0 0 2 2 2 1 Replication factor RFC1 C terminal domain BRCT PF00533.26 KKK20488.1 - 1.9e-15 57.0 0.0 7.7e-15 55.0 0.0 2.2 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.29 KKK20488.1 - 1e-10 42.1 0.3 3.3e-10 40.5 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KKK20488.1 - 6.1e-06 26.6 0.0 1.5e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KKK20488.1 - 0.00022 21.7 0.1 0.0016 18.8 0.1 2.4 1 1 0 1 1 1 1 AAA ATPase domain Rad17 PF03215.15 KKK20488.1 - 0.0013 18.7 0.0 0.003 17.5 0.0 1.6 1 0 0 1 1 1 1 Rad17 P-loop domain DNA_pol3_delta PF06144.13 KKK20488.1 - 0.0021 17.9 0.0 0.0047 16.7 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_33 PF13671.6 KKK20488.1 - 0.0058 16.8 0.0 0.016 15.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 KKK20488.1 - 0.011 15.5 0.0 0.024 14.4 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Bac_DnaA PF00308.18 KKK20488.1 - 0.015 15.1 0.3 2 8.2 0.1 2.7 3 0 0 3 3 3 0 Bacterial dnaA protein AAA_5 PF07728.14 KKK20488.1 - 0.028 14.4 0.0 0.41 10.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 KKK20488.1 - 0.04 14.5 0.2 0.24 11.9 0.0 2.5 3 0 0 3 3 1 0 AAA domain Sigma54_activat PF00158.26 KKK20488.1 - 0.041 13.6 0.0 0.084 12.6 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain CMV_1a PF12467.8 KKK20488.1 - 0.066 13.6 1.1 0.66 10.3 0.2 2.6 2 0 0 2 2 2 0 Cucumber mosaic virus 1a protein family AAA_28 PF13521.6 KKK20488.1 - 0.11 12.8 0.4 0.55 10.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain BRCT_2 PF16589.5 KKK20488.1 - 0.16 12.4 0.0 0.59 10.6 0.0 2.0 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain CRIM PF16978.5 KKK20489.1 - 1.8e-42 144.8 0.0 3e-42 144.1 0.0 1.4 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), middle CRIM domain SIN1_PH PF16979.5 KKK20489.1 - 1.4e-27 96.1 0.0 2.8e-27 95.1 0.0 1.5 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology PBP1_TM PF14812.6 KKK20489.1 - 0.0079 16.5 9.7 0.044 14.1 7.0 2.7 2 0 0 2 2 2 1 Transmembrane domain of transglycosylase PBP1 at N-terminal PH PF00169.29 KKK20489.1 - 0.017 15.6 0.0 0.039 14.5 0.0 1.6 1 0 0 1 1 1 0 PH domain AIM3 PF17096.5 KKK20489.1 - 0.11 13.4 1.0 0.48 11.4 1.0 2.1 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 3 CtaG_Cox11 PF04442.14 KKK20490.1 - 1.1e-59 200.8 0.0 1.5e-59 200.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 PNP_UDP_1 PF01048.20 KKK20491.1 - 0.00039 19.8 0.0 0.00062 19.1 0.0 1.3 1 0 0 1 1 1 1 Phosphorylase superfamily Mg_trans_NIPA PF05653.14 KKK20492.1 - 1e-90 303.9 24.6 1.3e-90 303.5 24.6 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 KKK20492.1 - 2.3e-05 24.6 7.1 2.3e-05 24.6 7.1 3.3 3 0 0 3 3 3 1 EamA-like transporter family DUF805 PF05656.14 KKK20492.1 - 3.4 8.1 11.3 5.3 7.5 1.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF805) Lectin_leg-like PF03388.13 KKK20493.1 - 4.4e-49 166.9 0.1 5.4e-49 166.6 0.1 1.0 1 0 0 1 1 1 1 Legume-like lectin family HERV-K_env_2 PF13804.6 KKK20494.1 - 0.068 12.9 0.0 0.098 12.4 0.0 1.2 1 0 0 1 1 1 0 Retro-transcribing viruses envelope glycoprotein RTA1 PF04479.13 KKK20495.1 - 1.7e-58 197.7 4.4 2.2e-58 197.3 4.4 1.2 1 0 0 1 1 1 1 RTA1 like protein ICMT PF04140.14 KKK20496.1 - 5.8e-09 36.3 4.0 5.4e-07 30.0 4.0 2.3 1 1 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 KKK20496.1 - 1.7e-06 28.4 3.1 4.2e-05 23.9 0.6 2.5 1 1 1 2 2 2 2 Phospholipid methyltransferase ERG4_ERG24 PF01222.17 KKK20496.1 - 0.03 13.1 0.3 0.047 12.4 0.3 1.3 1 0 0 1 1 1 0 Ergosterol biosynthesis ERG4/ERG24 family Aldo_ket_red PF00248.21 KKK20497.1 - 1.2e-50 172.4 0.0 1.3e-50 172.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Fungal_trans_2 PF11951.8 KKK20498.1 - 2.6e-06 26.5 0.3 3.5e-06 26.1 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK20498.1 - 0.0086 16.2 3.2 0.0086 16.2 3.2 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-piccolo PF05715.13 KKK20498.1 - 0.17 12.1 0.2 0.17 12.1 0.2 2.3 3 0 0 3 3 3 0 Piccolo Zn-finger MFS_1 PF07690.16 KKK20499.1 - 2.4e-39 135.3 57.2 2.4e-39 135.3 57.2 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF5305 PF17231.2 KKK20499.1 - 0.2 11.0 0.1 0.54 9.6 0.1 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5305) p450 PF00067.22 KKK20500.1 - 7.6e-71 239.2 0.0 8.8e-71 239.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Tmemb_14 PF03647.13 KKK20501.1 - 3.1e-12 47.1 3.0 4.1e-12 46.7 3.0 1.1 1 0 0 1 1 1 1 Transmembrane proteins 14C DUF2339 PF10101.9 KKK20501.1 - 0.0083 14.8 2.4 0.0094 14.6 2.4 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2339) DUF2530 PF10745.9 KKK20501.1 - 0.29 11.4 2.3 1.7 8.9 0.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2530) Bys1 PF04681.12 KKK20502.1 - 1.4e-15 57.6 0.9 1.6e-15 57.4 0.9 1.0 1 0 0 1 1 1 1 Blastomyces yeast-phase-specific protein MFS_1 PF07690.16 KKK20503.1 - 6.9e-20 71.3 55.4 1.2e-10 40.9 35.7 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MmgE_PrpD PF03972.14 KKK20504.1 - 4.3e-120 401.2 0.0 5.1e-120 401.0 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family FR47 PF08445.10 KKK20505.1 - 1.3e-05 25.0 0.0 2.2e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_1 PF00583.25 KKK20505.1 - 3.2e-05 24.2 0.0 4.4e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KKK20505.1 - 8.1e-05 22.6 0.2 0.00015 21.7 0.2 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KKK20505.1 - 0.00065 20.1 0.1 0.00099 19.5 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KKK20505.1 - 0.0039 17.3 0.0 0.013 15.6 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain GNAT_acetyltran PF12746.7 KKK20505.1 - 0.013 15.0 0.0 0.02 14.5 0.0 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase Peptidase_M35 PF02102.15 KKK20506.1 - 4.4e-165 548.9 14.6 5.2e-165 548.6 14.6 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.6 KKK20506.1 - 4.8e-44 150.4 5.0 4.8e-44 150.4 5.0 1.5 2 0 0 2 2 2 1 Lysine-specific metallo-endopeptidase HRXXH PF13933.6 KKK20506.1 - 0.004 16.7 2.5 0.0085 15.7 2.5 1.5 1 1 0 1 1 1 1 Putative peptidase family CARDB PF07705.11 KKK20506.1 - 0.18 12.1 3.9 0.47 10.7 0.4 3.1 2 2 1 3 3 3 0 CARDB tRNA-synt_1c_C PF03950.18 KKK20506.1 - 0.2 11.5 0.0 0.4 10.5 0.0 1.4 1 0 0 1 1 1 0 tRNA synthetases class I (E and Q), anti-codon binding domain HD PF01966.22 KKK20507.1 - 3.8e-05 23.9 0.0 5.3e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 HD domain HDOD PF08668.12 KKK20507.1 - 0.0065 16.0 0.0 0.0089 15.5 0.0 1.2 1 0 0 1 1 1 1 HDOD domain Fungal_trans PF04082.18 KKK20508.1 - 5.3e-08 32.2 0.9 8.6e-08 31.5 0.9 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Aconitase PF00330.20 KKK20509.1 - 9.8e-73 245.7 0.0 5.3e-71 240.0 0.0 2.1 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KKK20509.1 - 2.2e-16 60.4 0.0 4.2e-16 59.5 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain Aconitase_2_N PF06434.13 KKK20509.1 - 0.18 11.4 0.0 0.31 10.6 0.0 1.4 1 0 0 1 1 1 0 Aconitate hydratase 2 N-terminus PEP_mutase PF13714.6 KKK20510.1 - 3.3e-48 164.2 0.1 3.8e-48 164.0 0.1 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 KKK20510.1 - 3.6e-17 62.1 0.1 4.7e-17 61.7 0.1 1.1 1 0 0 1 1 1 1 Isocitrate lyase family Pantoate_transf PF02548.15 KKK20510.1 - 0.0076 15.7 0.0 0.097 12.0 0.0 2.3 2 0 0 2 2 2 1 Ketopantoate hydroxymethyltransferase APH PF01636.23 KKK20511.1 - 2e-09 37.7 0.1 6.2e-07 29.6 0.2 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family zf-C2H2_4 PF13894.6 KKK20512.1 - 0.0014 19.2 3.5 0.032 15.1 0.1 2.9 2 0 0 2 2 2 1 C2H2-type zinc finger zf-Di19 PF05605.12 KKK20512.1 - 0.006 16.8 1.7 0.63 10.4 0.1 2.3 2 0 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding Prok-RING_4 PF14447.6 KKK20512.1 - 0.0062 16.4 0.7 1.6 8.6 0.1 2.4 2 0 0 2 2 2 2 Prokaryotic RING finger family 4 zf-C2H2_2 PF12756.7 KKK20512.1 - 0.0082 16.5 0.2 0.025 14.9 0.2 1.7 1 1 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-C2H2_9 PF16293.5 KKK20512.1 - 0.063 13.1 0.1 12 5.8 0.0 2.5 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) DZR PF12773.7 KKK20512.1 - 0.12 12.4 0.0 0.25 11.4 0.0 1.5 1 1 0 1 1 1 0 Double zinc ribbon zf-C2H2 PF00096.26 KKK20512.1 - 0.12 12.8 2.2 2.2 8.9 0.1 3.0 3 0 0 3 3 3 0 Zinc finger, C2H2 type UPF0547 PF10571.9 KKK20512.1 - 0.38 10.9 2.5 0.81 9.8 0.2 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 Acetyltransf_1 PF00583.25 KKK20513.1 - 1.4e-10 41.4 0.0 1.7e-10 41.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KKK20513.1 - 3.4e-07 30.6 0.2 1.2e-06 28.8 0.1 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KKK20513.1 - 8.1e-07 29.0 0.1 2.7e-06 27.4 0.1 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KKK20513.1 - 0.0031 17.4 0.1 0.0067 16.4 0.1 1.6 1 1 0 1 1 1 1 FR47-like protein Synapsin_N PF10581.9 KKK20513.1 - 0.11 12.4 0.1 0.25 11.3 0.1 1.5 1 0 0 1 1 1 0 Synapsin N-terminal p450 PF00067.22 KKK20514.1 - 3.8e-51 174.3 0.0 5.1e-51 173.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 PIG-L PF02585.17 KKK20515.1 - 9e-17 61.9 0.0 1.8e-16 61.0 0.0 1.5 1 1 0 1 1 1 1 GlcNAc-PI de-N-acetylase Sugar_tr PF00083.24 KKK20516.1 - 4.3e-73 246.7 16.9 5.9e-73 246.3 16.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKK20516.1 - 4.9e-15 55.3 32.5 5.7e-15 55.1 28.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily GFO_IDH_MocA PF01408.22 KKK20516.1 - 5.7e-07 30.4 0.0 1.2e-06 29.4 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KKK20516.1 - 0.00021 21.3 0.0 0.00047 20.2 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Glyco_hydro_17 PF00332.18 KKK20518.1 - 1.3e-07 31.5 1.1 2.4e-07 30.7 1.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 HTH_6 PF01418.17 KKK20518.1 - 0.067 13.2 0.0 0.29 11.1 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain, rpiR family PQQ PF01011.21 KKK20518.1 - 0.12 12.4 0.5 0.3 11.1 0.5 1.7 1 0 0 1 1 1 0 PQQ enzyme repeat Sugar_tr PF00083.24 KKK20519.1 - 3.1e-77 260.4 17.6 3.8e-77 260.1 17.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKK20519.1 - 1.3e-26 93.4 16.9 1.9e-26 92.9 16.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Ribonuclease PF00545.20 KKK20520.1 - 3.4e-07 30.9 0.3 4.7e-07 30.5 0.3 1.3 1 0 0 1 1 1 1 ribonuclease MARVEL PF01284.23 KKK20521.1 - 0.00044 20.3 1.0 0.005 16.9 0.1 2.4 2 0 0 2 2 2 1 Membrane-associating domain Otopetrin PF03189.13 KKK20521.1 - 0.027 13.3 1.6 0.04 12.7 1.6 1.2 1 0 0 1 1 1 0 Otopetrin DUF2474 PF10617.9 KKK20521.1 - 8.6 6.3 6.9 6 6.8 0.6 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2474) ABC_membrane PF00664.23 KKK20522.1 - 7.6e-52 176.6 41.4 2.5e-34 119.2 19.9 3.1 3 0 0 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.27 KKK20522.1 - 2.6e-49 167.2 0.0 1.4e-27 96.9 0.0 2.8 2 0 0 2 2 2 2 ABC transporter MMR_HSR1 PF01926.23 KKK20522.1 - 2.7e-07 30.6 0.5 0.017 15.2 0.1 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase SMC_N PF02463.19 KKK20522.1 - 6.3e-07 29.0 0.5 0.56 9.6 0.0 3.6 2 1 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KKK20522.1 - 7.4e-07 29.3 2.4 0.088 12.6 0.4 3.7 2 2 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KKK20522.1 - 2.5e-06 28.0 0.4 0.08 13.3 0.0 3.3 3 1 0 3 3 2 2 AAA ATPase domain AAA_29 PF13555.6 KKK20522.1 - 2.8e-05 23.7 4.8 0.025 14.3 0.0 2.8 3 0 0 3 3 2 2 P-loop containing region of AAA domain Dynamin_N PF00350.23 KKK20522.1 - 6.2e-05 23.1 1.1 0.012 15.7 0.0 2.6 2 0 0 2 2 2 1 Dynamin family AAA_23 PF13476.6 KKK20522.1 - 6.8e-05 23.5 0.1 0.38 11.2 0.1 2.5 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 KKK20522.1 - 7e-05 22.8 0.9 0.04 13.8 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase Zeta_toxin PF06414.12 KKK20522.1 - 0.00012 21.4 0.0 0.032 13.5 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin AAA_22 PF13401.6 KKK20522.1 - 0.00051 20.3 1.2 1.1 9.5 0.0 3.3 2 1 0 2 2 2 2 AAA domain DUF87 PF01935.17 KKK20522.1 - 0.0087 16.2 0.6 0.25 11.4 0.2 2.3 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_18 PF13238.6 KKK20522.1 - 0.019 15.5 0.2 4.5 7.8 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KKK20522.1 - 0.022 14.5 1.6 2.5 7.8 0.2 2.7 2 1 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 KKK20522.1 - 0.03 14.0 0.0 1.1 8.9 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein ATP_bind_1 PF03029.17 KKK20522.1 - 0.045 13.5 1.0 5 6.8 0.1 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA PF00004.29 KKK20522.1 - 0.048 14.1 0.1 2.4 8.6 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Ploopntkinase3 PF18751.1 KKK20522.1 - 0.063 13.2 0.1 12 5.7 0.0 2.4 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 AAA_15 PF13175.6 KKK20522.1 - 0.064 13.0 0.2 5.3 6.7 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_27 PF13514.6 KKK20522.1 - 0.073 12.7 0.0 2.4 7.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 KKK20522.1 - 0.079 13.2 0.1 18 5.6 0.1 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_25 PF13481.6 KKK20522.1 - 0.088 12.4 0.8 2.3 7.7 0.0 2.7 3 0 0 3 3 3 0 AAA domain CDC45 PF02724.14 KKK20522.1 - 0.19 10.0 0.0 0.36 9.1 0.0 1.3 1 0 0 1 1 1 0 CDC45-like protein AAA_PrkA PF08298.11 KKK20522.1 - 0.2 10.6 0.1 0.94 8.3 0.0 2.0 2 0 0 2 2 2 0 PrkA AAA domain AAA_28 PF13521.6 KKK20522.1 - 0.84 9.9 3.2 1.9 8.7 0.1 2.7 2 0 0 2 2 2 0 AAA domain Phosphoesterase PF04185.14 KKK20523.1 - 2.6e-63 214.4 0.3 4e-63 213.8 0.3 1.3 1 0 0 1 1 1 1 Phosphoesterase family Glyco_hydro_43 PF04616.14 KKK20524.1 - 1.5e-102 342.8 0.9 3.5e-102 341.6 0.3 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 KKK20524.1 - 9.6e-45 152.8 0.0 1.4e-44 152.3 0.0 1.2 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain Glyco_hydro_28 PF00295.17 KKK20525.1 - 1.3e-93 313.6 19.7 1.3e-93 313.6 19.7 2.2 2 0 0 2 2 2 1 Glycosyl hydrolases family 28 Pectinesterase PF01095.19 KKK20525.1 - 1.4e-36 125.8 2.8 5.3e-36 123.9 1.4 2.3 2 0 0 2 2 2 1 Pectinesterase ArAE_2_N PF10337.9 KKK20526.1 - 5.5e-119 398.3 1.4 1.1e-118 397.3 1.4 1.4 1 0 0 1 1 1 1 Putative ER transporter, 6TM, N-terminal ArAE_2 PF10334.9 KKK20526.1 - 2.4e-57 194.4 0.0 2.3e-55 188.0 0.0 2.4 2 0 0 2 2 2 1 Aromatic acid exporter family member 2 FUSC_2 PF13515.6 KKK20526.1 - 2.2e-09 37.5 14.9 2.2e-09 37.5 14.9 3.8 3 1 1 4 4 4 1 Fusaric acid resistance protein-like ALMT PF11744.8 KKK20526.1 - 6.3 5.5 14.1 0.91 8.3 9.6 1.7 2 0 0 2 2 2 0 Aluminium activated malate transporter Aa_trans PF01490.18 KKK20527.1 - 3.8e-30 104.9 30.7 8.6e-30 103.8 30.7 1.5 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein S1 PF00575.23 KKK20536.1 - 2.4e-65 216.8 25.2 2.2e-12 47.2 0.9 11.7 11 0 0 11 11 11 10 S1 RNA binding domain TPR_14 PF13428.6 KKK20536.1 - 5.2e-07 29.9 0.4 0.8 10.7 0.1 5.4 3 2 2 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 KKK20536.1 - 1.3e-06 28.8 0.1 0.033 14.7 0.1 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat Suf PF05843.14 KKK20536.1 - 1.7e-05 25.0 0.8 0.14 12.2 0.1 3.5 1 1 1 2 2 2 2 Suppressor of forked protein (Suf) RNase_II_C_S1 PF18614.1 KKK20536.1 - 4.3e-05 23.4 7.1 1.3 9.0 0.0 6.4 7 0 0 7 7 7 2 RNase II-type exonuclease C-terminal S1 domain PPR PF01535.20 KKK20536.1 - 0.0058 16.8 0.1 2 8.9 0.0 3.5 3 0 0 3 3 3 1 PPR repeat TPR_16 PF13432.6 KKK20536.1 - 0.018 15.6 0.1 60 4.4 0.0 3.7 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 KKK20536.1 - 0.021 15.0 0.5 2.5 8.5 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat NRDE-2 PF08424.10 KKK20536.1 - 0.024 13.8 0.0 0.76 8.8 0.1 2.5 2 0 0 2 2 2 0 NRDE-2, necessary for RNA interference TPR_7 PF13176.6 KKK20536.1 - 0.071 13.2 0.5 2.3 8.4 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 KKK20536.1 - 0.11 12.7 1.7 7 7.0 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 KKK20536.1 - 0.11 13.2 1.1 1.1e+02 3.7 0.1 4.4 4 0 0 4 4 3 0 Tetratricopeptide repeat S1_2 PF13509.6 KKK20536.1 - 0.13 12.3 0.1 3.6 7.7 0.0 3.4 3 0 0 3 3 2 0 S1 domain TPR_15 PF13429.6 KKK20536.1 - 0.16 11.1 0.3 0.81 8.8 0.3 2.1 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_12 PF13424.6 KKK20536.1 - 0.29 11.5 0.5 23 5.3 0.0 3.4 2 1 1 3 3 3 0 Tetratricopeptide repeat WD40 PF00400.32 KKK20537.1 - 8.2e-14 51.8 0.6 0.013 16.3 0.0 5.6 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKK20537.1 - 5.9e-05 23.3 0.0 3.6 8.0 0.0 4.7 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KKK20537.1 - 0.091 12.1 0.0 0.16 11.2 0.0 1.4 1 0 0 1 1 1 0 WD40-like domain Cpn60_TCP1 PF00118.24 KKK20538.1 - 1.3e-150 502.3 17.2 1.5e-150 502.1 17.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family ProRS-C_1 PF09180.11 KKK20539.1 - 1.3e-23 82.9 1.5 2.9e-23 81.8 1.5 1.6 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.25 KKK20539.1 - 7.1e-19 68.5 0.0 1.3e-18 67.6 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 KKK20539.1 - 1.3e-11 44.5 0.0 2.9e-11 43.4 0.0 1.7 1 0 0 1 1 1 1 Anticodon binding domain STAG PF08514.11 KKK20540.1 - 1.2e-35 121.9 2.0 1.2e-35 121.9 2.0 3.1 3 0 0 3 3 3 1 STAG domain YL1 PF05764.13 KKK20540.1 - 0.0055 16.9 11.4 0.0055 16.9 11.4 4.6 4 1 1 5 5 5 1 YL1 nuclear protein HEAT_2 PF13646.6 KKK20540.1 - 0.011 16.1 4.7 0.39 11.2 0.2 4.3 3 1 1 4 4 4 0 HEAT repeats HEAT PF02985.22 KKK20540.1 - 0.1 12.9 0.0 1e+02 3.6 0.0 4.5 6 0 0 6 6 6 0 HEAT repeat DUF5596 PF18082.1 KKK20540.1 - 0.11 12.3 0.7 0.43 10.4 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5596) BAG6 PF12057.8 KKK20540.1 - 0.15 11.8 0.1 0.47 10.1 0.1 1.8 1 0 0 1 1 1 0 BCL2-associated athanogene 6 FlgM PF04316.13 KKK20540.1 - 0.73 10.2 8.6 0.49 10.8 1.4 3.9 4 0 0 4 4 4 0 Anti-sigma-28 factor, FlgM UreD PF01774.17 KKK20541.1 - 1.5e-66 224.3 0.0 2e-66 224.0 0.0 1.1 1 0 0 1 1 1 1 UreD urease accessory protein Tir_receptor_N PF07490.11 KKK20541.1 - 0.11 12.3 1.4 0.19 11.5 1.1 1.5 1 1 0 1 1 1 0 Translocated intimin receptor (Tir) N-terminus Stm1_N PF09598.10 KKK20541.1 - 0.23 12.3 7.5 2 9.3 3.4 2.8 2 0 0 2 2 2 0 Stm1 DUF2729 PF10870.8 KKK20542.1 - 0.057 13.3 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2729) C_Hendra PF16821.5 KKK20543.1 - 0.0023 17.8 3.3 0.0023 17.8 3.3 3.5 2 1 1 4 4 4 1 C protein from hendra and measles viruses SOG2 PF10428.9 KKK20543.1 - 3.6 6.7 18.6 5.1 6.2 18.6 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein Pro_dh PF01619.18 KKK20556.1 - 2e-62 211.4 0.0 2.6e-62 211.1 0.0 1.1 1 0 0 1 1 1 1 Proline dehydrogenase AAA_assoc PF14363.6 KKK20556.1 - 0.018 15.4 0.0 0.037 14.4 0.0 1.5 1 0 0 1 1 1 0 Domain associated at C-terminal with AAA Glyco_hydro_65N PF03636.15 KKK20557.1 - 3.3e-32 112.0 0.0 5.3e-32 111.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Glyco_hydro_65m PF03632.15 KKK20557.1 - 7e-25 87.7 4.9 1.8e-19 69.9 0.7 2.3 1 1 1 2 2 2 2 Glycosyl hydrolase family 65 central catalytic domain Glyco_hydro_65C PF03633.15 KKK20557.1 - 0.00078 19.3 0.2 0.0026 17.7 0.2 1.9 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, C-terminal domain Catalase PF00199.19 KKK20558.1 - 8.6e-164 545.2 0.1 1.1e-163 544.9 0.1 1.1 1 0 0 1 1 1 1 Catalase Catalase_C PF18011.1 KKK20558.1 - 2.3e-49 167.0 0.0 3.5e-49 166.4 0.0 1.3 1 0 0 1 1 1 1 C-terminal domain found in long catalases Catalase-rel PF06628.12 KKK20558.1 - 9e-16 57.9 0.0 1.9e-15 56.8 0.0 1.6 1 0 0 1 1 1 1 Catalase-related immune-responsive Kin17_mid PF10357.9 KKK20559.1 - 1.1e-49 167.5 2.8 1.1e-49 167.5 2.8 1.9 2 0 0 2 2 2 1 Domain of Kin17 curved DNA-binding protein zf-C2H2_jaz PF12171.8 KKK20559.1 - 0.0004 20.6 1.1 0.00086 19.5 1.1 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KKK20559.1 - 0.0013 19.1 3.9 0.0018 18.6 2.3 2.1 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 KKK20559.1 - 0.51 10.7 5.8 0.17 12.2 0.8 2.4 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) AC_N PF16214.5 KKK20559.1 - 0.88 8.6 4.5 1.3 8.1 4.5 1.2 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region Actin PF00022.19 KKK20560.1 - 8.9e-24 83.8 0.0 1.2e-18 67.0 0.0 3.1 3 0 0 3 3 3 3 Actin Actin_micro PF17003.5 KKK20560.1 - 0.21 10.7 0.0 0.35 10.0 0.0 1.2 1 0 0 1 1 1 0 Putative actin-like family TT_ORF2 PF02957.15 KKK20560.1 - 0.23 12.4 11.2 0.22 12.5 0.5 2.9 2 0 0 2 2 2 0 TT viral ORF2 CBFD_NFYB_HMF PF00808.23 KKK20561.1 - 1.4e-17 63.7 0.2 2.5e-17 62.9 0.2 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KKK20561.1 - 1e-07 32.3 1.7 2.3e-07 31.2 0.0 1.9 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.13 KKK20561.1 - 0.0075 16.2 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated DUF5333 PF17267.2 KKK20561.1 - 0.063 13.5 0.4 0.084 13.1 0.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5333) YolD PF08863.10 KKK20561.1 - 0.57 10.3 8.3 0.32 11.1 6.4 1.5 2 0 0 2 2 2 0 YolD-like protein adh_short PF00106.25 KKK20562.1 - 8.8e-43 146.0 0.0 1e-42 145.8 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KKK20562.1 - 1.8e-29 103.0 0.0 2.2e-29 102.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KKK20562.1 - 3.6e-10 40.1 0.2 5.5e-10 39.4 0.2 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KKK20562.1 - 0.00072 19.5 0.0 0.0012 18.8 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KKK20562.1 - 0.0018 17.8 0.0 0.02 14.4 0.0 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 KKK20562.1 - 0.027 14.5 0.0 0.043 13.9 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 KKK20562.1 - 0.066 13.8 0.0 0.15 12.7 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DAO PF01266.24 KKK20563.1 - 2.2e-36 126.2 0.0 2.7e-36 125.9 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KKK20563.1 - 0.0049 17.1 0.1 0.011 16.0 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KKK20563.1 - 0.0062 17.1 0.0 0.057 14.0 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KKK20563.1 - 0.082 12.9 0.1 0.22 11.5 0.0 1.7 2 0 0 2 2 2 0 FAD-NAD(P)-binding SMC_Nse1 PF07574.13 KKK20564.1 - 7.3e-67 225.0 0.0 1.3e-66 224.2 0.0 1.4 1 0 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex zf-CCCH PF00642.24 KKK20564.1 - 5.2e-07 29.4 20.0 9e-07 28.7 2.5 2.8 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_1 PF00076.22 KKK20564.1 - 0.002 17.9 0.1 0.0052 16.6 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf_CCCH_4 PF18345.1 KKK20564.1 - 0.016 15.2 3.3 0.016 15.2 3.3 3.1 3 0 0 3 3 3 0 Zinc finger domain Torus PF16131.5 KKK20564.1 - 0.084 13.6 2.9 1.6 9.5 0.3 2.4 2 0 0 2 2 2 0 Torus domain Pkinase PF00069.25 KKK20565.1 - 0.00012 21.6 0.0 0.00095 18.6 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain AsmA_1 PF13109.6 KKK20565.1 - 0.016 14.7 0.1 0.024 14.1 0.1 1.2 1 0 0 1 1 1 0 AsmA-like C-terminal region CLASP_N PF12348.8 KKK20576.1 - 4.4e-154 510.6 2.0 1.2e-87 293.3 0.0 2.2 2 0 0 2 2 2 2 CLASP N terminal HEAT PF02985.22 KKK20576.1 - 2.9e-10 39.5 0.0 0.014 15.6 0.0 5.7 5 0 0 5 5 5 2 HEAT repeat Cnd1 PF12717.7 KKK20576.1 - 3.8e-06 27.0 0.2 0.078 13.0 0.0 3.7 3 1 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KKK20576.1 - 3.3e-05 24.2 0.9 1 9.8 0.1 3.7 3 0 0 3 3 3 2 HEAT repeats HEAT_EZ PF13513.6 KKK20576.1 - 0.0011 19.4 0.1 1.3 9.6 0.0 3.5 3 0 0 3 3 3 1 HEAT-like repeat Adaptin_N PF01602.20 KKK20576.1 - 0.038 12.6 0.5 0.67 8.4 0.1 2.7 2 1 1 3 3 3 0 Adaptin N terminal region Condensin2nSMC PF12422.8 KKK20576.1 - 0.084 13.0 0.1 4 7.6 0.1 2.9 3 0 0 3 3 3 0 Condensin II non structural maintenance of chromosomes subunit DUF3361 PF11841.8 KKK20576.1 - 0.18 11.8 0.5 0.47 10.4 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3361) RhoGAP PF00620.27 KKK20577.1 - 3.9e-48 163.1 0.3 1.1e-47 161.7 0.0 1.9 2 0 0 2 2 2 1 RhoGAP domain LIM PF00412.22 KKK20577.1 - 1.3e-13 51.0 20.7 4.8e-09 36.3 4.3 2.5 2 0 0 2 2 2 2 LIM domain Fez1 PF06818.15 KKK20577.1 - 0.034 14.6 16.1 0.047 14.1 12.0 2.6 1 1 1 2 2 2 0 Fez1 AAA_23 PF13476.6 KKK20577.1 - 0.077 13.5 3.8 0.18 12.2 3.8 1.6 1 0 0 1 1 1 0 AAA domain DUF536 PF04394.14 KKK20577.1 - 0.64 9.9 3.9 4 7.4 1.3 2.6 2 0 0 2 2 2 0 Protein of unknown function, DUF536 CENP-H PF05837.12 KKK20577.1 - 1.3 9.4 12.4 0.31 11.4 2.0 3.4 2 1 1 3 3 3 0 Centromere protein H (CENP-H) TF_Zn_Ribbon PF08271.12 KKK20577.1 - 3.7 7.2 18.8 1.8 8.1 1.1 5.1 4 1 1 5 5 5 0 TFIIB zinc-binding Ribonuclease_3 PF00636.26 KKK20578.1 - 2.6e-08 34.4 0.0 7.6e-08 32.9 0.0 1.8 1 1 0 1 1 1 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 KKK20578.1 - 1.1e-07 32.0 0.0 0.00077 19.6 0.0 2.3 2 0 0 2 2 2 2 Ribonuclease-III-like dsrm PF00035.26 KKK20578.1 - 5e-07 30.3 0.0 1.1e-06 29.2 0.0 1.6 1 0 0 1 1 1 1 Double-stranded RNA binding motif BSP PF04450.12 KKK20579.1 - 4.1e-72 242.3 0.0 5.6e-72 241.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase of plants and bacteria Peptidase_M91 PF14891.6 KKK20579.1 - 0.16 12.3 0.0 0.19 12.0 0.0 1.3 1 0 0 1 1 1 0 Effector protein CAP_N PF01213.19 KKK20580.1 - 1.9e-112 375.8 8.4 9.7e-112 373.5 8.4 2.0 1 1 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.11 KKK20580.1 - 4.1e-55 185.7 0.9 6.1e-55 185.1 0.9 1.3 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.12 KKK20580.1 - 0.027 14.2 3.6 2.7 7.7 4.1 2.2 1 1 1 2 2 2 0 Tubulin binding cofactor C PfkB PF00294.24 KKK20581.1 - 5.7e-13 48.8 0.0 2.5e-12 46.7 0.0 1.9 1 1 0 1 1 1 1 pfkB family carbohydrate kinase LicD PF04991.13 KKK20584.1 - 2.4e-25 90.0 5.9 6.2e-18 65.8 2.8 2.2 1 1 1 2 2 2 2 LicD family UvrD-helicase PF00580.21 KKK20584.1 - 0.062 12.8 0.1 0.09 12.3 0.1 1.3 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain HSP70 PF00012.20 KKK20585.1 - 4.6e-150 500.7 1.7 4.6e-150 500.7 1.7 2.2 1 1 1 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 KKK20585.1 - 5e-11 42.0 0.0 9.4e-11 41.1 0.0 1.3 1 0 0 1 1 1 1 MreB/Mbl protein Peptidase_M22 PF00814.25 KKK20585.1 - 0.034 13.9 0.2 6.3 6.4 0.1 2.4 2 0 0 2 2 2 0 Glycoprotease family DUF2746 PF10874.8 KKK20585.1 - 0.035 14.5 0.0 0.24 11.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2746) FGGY_C PF02782.16 KKK20585.1 - 0.1 12.3 0.1 0.34 10.6 0.0 2.0 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain Ketoacyl-synt_C PF02801.22 KKK20585.1 - 0.14 12.1 0.0 0.6 10.1 0.0 2.1 1 0 0 1 1 1 0 Beta-ketoacyl synthase, C-terminal domain APH PF01636.23 KKK20586.1 - 4e-05 23.7 0.0 4.8e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Thiolase_N PF00108.23 KKK20587.1 - 6.8e-71 238.7 0.2 1.1e-70 238.0 0.2 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KKK20587.1 - 7e-40 135.5 0.4 7e-40 135.5 0.4 1.8 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KKK20587.1 - 0.00085 19.0 1.5 0.0054 16.3 1.2 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 KKK20587.1 - 0.02 14.7 0.1 1 9.3 0.0 2.7 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III DASH_Ask1 PF08655.10 KKK20589.1 - 8.1e-31 105.7 0.1 1.6e-30 104.8 0.1 1.5 1 0 0 1 1 1 1 DASH complex subunit Ask1 WLM PF08325.10 KKK20590.1 - 3.7e-50 170.7 0.6 6.1e-50 169.9 0.0 1.6 2 0 0 2 2 2 1 WLM domain DUF45 PF01863.17 KKK20590.1 - 7.6e-05 22.8 0.4 0.00014 22.0 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function DUF45 SprT-like PF10263.9 KKK20590.1 - 0.047 13.5 3.4 0.14 12.1 3.4 1.9 1 1 0 1 1 1 0 SprT-like family ubiquitin PF00240.23 KKK20590.1 - 0.13 12.0 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin family LIM PF00412.22 KKK20595.1 - 2.1e-13 50.2 15.4 1.2e-07 31.9 4.2 2.8 2 1 0 2 2 2 2 LIM domain DUF2321 PF10083.9 KKK20595.1 - 0.077 12.6 6.0 0.36 10.4 0.3 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2321) Zn_ribbon_17 PF17120.5 KKK20595.1 - 3.4 7.4 13.7 0.26 11.0 2.6 2.8 2 1 0 2 2 2 0 Zinc-ribbon, C4HC2 type Methyltransf_4 PF02390.17 KKK20596.1 - 0.0036 16.8 0.0 0.0059 16.1 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.6 KKK20596.1 - 0.088 13.5 0.3 1.1 10.0 0.1 2.3 2 1 0 2 2 2 0 Methyltransferase domain Ribonuc_L-PSP PF01042.21 KKK20597.1 - 2.6e-23 82.3 0.0 3e-23 82.1 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Cu-oxidase_2 PF07731.14 KKK20598.1 - 4.6e-49 165.7 10.0 1.4e-42 144.7 2.1 3.6 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 KKK20598.1 - 1.7e-40 137.7 6.3 5.8e-38 129.6 1.5 3.4 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 KKK20598.1 - 6.5e-40 136.8 3.9 9e-34 116.9 0.4 3.6 3 0 0 3 3 3 3 Multicopper oxidase Cupredoxin_1 PF13473.6 KKK20598.1 - 0.0049 16.9 0.0 6.7 6.9 0.0 3.8 4 0 0 4 4 4 1 Cupredoxin-like domain Self-incomp_S1 PF05938.11 KKK20598.1 - 0.031 14.8 0.1 8.4 7.0 0.1 2.4 2 0 0 2 2 2 0 Plant self-incompatibility protein S1 DUF924 PF06041.11 KKK20599.1 - 1.2e-48 165.7 5.0 7.6e-48 163.0 5.0 2.0 1 1 0 1 1 1 1 Bacterial protein of unknown function (DUF924) RNA_pol_3_Rpc31 PF11705.8 KKK20599.1 - 0.14 12.4 7.1 0.27 11.4 7.1 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 DNA_pol_phi PF04931.13 KKK20599.1 - 1.6 6.7 5.6 2.6 6.1 5.6 1.2 1 0 0 1 1 1 0 DNA polymerase phi Fe_hyd_lg_C PF02906.14 KKK20601.1 - 7.4e-53 179.7 0.0 1.5e-52 178.7 0.0 1.4 1 1 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain FTR1 PF03239.14 KKK20602.1 - 1.9e-83 280.2 8.4 2.4e-83 279.8 8.4 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family Cation_efflux PF01545.21 KKK20602.1 - 0.012 15.4 2.9 0.012 15.4 2.9 1.9 2 1 0 2 2 2 0 Cation efflux family GPDPase_memb PF10110.9 KKK20602.1 - 0.55 9.0 7.5 0.92 8.2 1.0 2.5 2 0 0 2 2 2 0 Membrane domain of glycerophosphoryl diester phosphodiesterase Sec7_N PF12783.7 KKK20603.1 - 6.5e-44 149.6 0.5 6.5e-44 149.6 0.5 4.4 4 1 0 4 4 4 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DCB PF16213.5 KKK20603.1 - 7.5e-41 139.7 4.6 3e-40 137.8 4.6 2.2 1 0 0 1 1 1 1 Dimerisation and cyclophilin-binding domain of Mon2 Mon2_C PF16206.5 KKK20603.1 - 8.6e-22 77.1 2.2 1.6e-21 76.2 1.3 1.9 2 0 0 2 2 2 1 C-terminal region of Mon2 protein DUF1981 PF09324.10 KKK20603.1 - 0.098 12.5 0.1 21 5.0 0.0 4.2 3 0 0 3 3 3 0 Domain of unknown function (DUF1981) DIOX_N PF14226.6 KKK20604.1 - 9.4e-28 97.3 0.0 1.5e-27 96.7 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KKK20604.1 - 2.7e-17 63.1 0.0 4.8e-17 62.3 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily TMEM51 PF15345.6 KKK20605.1 - 0.031 14.1 0.2 0.18 11.7 0.0 2.2 2 1 0 2 2 2 0 Transmembrane protein 51 Gram_pos_anchor PF00746.21 KKK20605.1 - 0.7 9.9 0.0 0.7 9.9 0.0 2.7 3 0 0 3 3 3 0 LPXTG cell wall anchor motif NPAT_C PF15712.5 KKK20605.1 - 4.9 5.7 7.7 6.2 5.3 7.7 1.2 1 0 0 1 1 1 0 NPAT C terminus RWD PF05773.22 KKK20607.1 - 3.8e-25 88.4 2.3 3.8e-25 88.4 2.3 1.6 2 0 0 2 2 2 1 RWD domain DFRP_C PF16543.5 KKK20607.1 - 0.15 12.6 15.8 1.3 9.5 15.8 2.5 1 1 1 2 2 2 0 DRG Family Regulatory Proteins, Tma46 Cyclin_N PF00134.23 KKK20608.1 - 4.6e-45 152.4 0.1 1.9e-44 150.5 0.1 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KKK20608.1 - 7.4e-34 116.4 0.0 1.6e-33 115.3 0.0 1.6 1 0 0 1 1 1 1 Cyclin, C-terminal domain UQ_con PF00179.26 KKK20609.1 - 4.6e-16 58.7 0.0 5e-16 58.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Abhydrolase_6 PF12697.7 KKK20610.1 - 4.3e-13 50.4 3.0 6.3e-13 49.8 2.8 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KKK20610.1 - 4.8e-08 32.6 0.0 8e-08 31.8 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KKK20610.1 - 3.3e-05 23.7 0.0 4.6e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Chlorophyllase2 PF12740.7 KKK20610.1 - 0.055 12.4 0.0 0.088 11.7 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme PGAP1 PF07819.13 KKK20610.1 - 0.081 12.6 0.1 0.13 11.9 0.1 1.3 1 0 0 1 1 1 0 PGAP1-like protein Ceramidase PF05875.12 KKK20611.1 - 2.2e-76 256.8 6.9 1.1e-51 175.8 1.2 2.0 1 1 1 2 2 2 2 Ceramidase DUF4199 PF13858.6 KKK20611.1 - 1.3 9.4 9.5 1.1 9.7 7.1 2.0 2 1 1 3 3 3 0 Protein of unknown function (DUF4199) Mito_carr PF00153.27 KKK20612.1 - 9.4e-52 172.9 3.7 3e-18 65.5 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein ESCRT-II PF05871.12 KKK20613.1 - 8.8e-50 168.6 0.9 1.2e-49 168.2 0.9 1.2 1 0 0 1 1 1 1 ESCRT-II complex subunit RTT107_BRCT_5 PF16770.5 KKK20614.1 - 2.6e-34 117.1 0.0 1.7e-30 104.9 0.0 4.2 4 0 0 4 4 4 1 Regulator of Ty1 transposition protein 107 BRCT domain PTCB-BRCT PF12738.7 KKK20614.1 - 3.2e-30 103.9 0.4 1.2e-19 70.0 0.2 5.2 4 1 0 4 4 4 4 twin BRCT domain BRCT PF00533.26 KKK20614.1 - 7.9e-25 87.1 0.0 2.3e-06 27.9 0.0 6.4 6 1 0 6 6 6 4 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 KKK20614.1 - 3.3e-24 85.1 0.0 7.3e-05 23.1 0.0 6.7 7 0 0 7 7 7 5 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 KKK20614.1 - 2.6e-08 34.0 0.0 0.046 14.0 0.0 3.8 3 0 0 3 3 3 3 DNA ligase 3 BRCT domain PRCC PF10253.9 KKK20614.1 - 0.15 12.8 6.6 0.39 11.5 6.6 1.6 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting Prefoldin_2 PF01920.20 KKK20615.1 - 3.5e-09 36.6 0.3 4.9e-09 36.1 0.2 1.3 1 1 0 1 1 1 1 Prefoldin subunit Ribosomal_L10 PF00466.20 KKK20616.1 - 0.032 14.4 0.0 0.71 10.1 0.0 2.6 1 1 0 1 1 1 0 Ribosomal protein L10 Glycos_transf_3 PF00591.21 KKK20617.1 - 1.2e-46 159.4 0.0 9.3e-44 149.9 0.0 3.1 1 1 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.17 KKK20617.1 - 1.8e-08 34.1 0.3 4e-08 33.0 0.3 1.6 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain DUF3349 PF11829.8 KKK20617.1 - 0.043 14.6 0.2 17 6.3 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3349) DNA_RNApol_7kD PF03604.13 KKK20618.1 - 1.1e-17 63.4 6.3 1.4e-17 63.1 6.3 1.1 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit DUF2197 PF09963.9 KKK20618.1 - 0.00032 20.9 0.9 0.041 14.1 0.0 2.1 1 1 1 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2197) zf_UBZ PF18439.1 KKK20618.1 - 0.0019 17.7 0.8 1.4 8.6 0.2 2.1 2 0 0 2 2 2 2 Ubiquitin-Binding Zinc Finger DZR PF12773.7 KKK20618.1 - 0.0044 17.0 0.3 0.0063 16.5 0.3 1.2 1 0 0 1 1 1 1 Double zinc ribbon zinc-ribbon_6 PF10005.9 KKK20618.1 - 0.0063 17.2 0.4 0.0077 16.9 0.4 1.1 1 0 0 1 1 1 1 zinc-ribbon domain zinc-ribbons_6 PF07191.12 KKK20618.1 - 0.0082 16.1 0.7 0.011 15.7 0.7 1.2 1 0 0 1 1 1 1 zinc-ribbons HypA PF01155.19 KKK20618.1 - 0.012 15.6 0.3 0.015 15.3 0.3 1.1 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn-ribbon_8 PF09723.10 KKK20618.1 - 0.013 15.6 1.2 0.027 14.6 1.2 1.6 1 1 0 1 1 1 0 Zinc ribbon domain DUF2318 PF10080.9 KKK20618.1 - 0.023 14.8 0.2 0.028 14.5 0.2 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) TFIIS_C PF01096.18 KKK20618.1 - 0.026 14.4 0.3 4 7.4 0.2 2.3 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) PhnA_Zn_Ribbon PF08274.12 KKK20618.1 - 0.027 14.4 0.2 0.04 13.9 0.2 1.2 1 0 0 1 1 1 0 PhnA Zinc-Ribbon zf-ISL3 PF14690.6 KKK20618.1 - 0.35 11.6 0.6 0.35 11.6 0.6 2.0 1 1 1 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Zn_ribbon_recom PF13408.6 KKK20618.1 - 0.39 11.3 5.7 2.5 8.7 1.1 2.1 1 1 1 2 2 2 0 Recombinase zinc beta ribbon domain DUF1295 PF06966.12 KKK20619.1 - 6.4e-10 38.9 0.0 9.7e-10 38.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.16 KKK20619.1 - 5.7e-05 23.1 0.0 0.00012 22.1 0.0 1.5 1 1 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase SKI PF01202.22 KKK20620.1 - 2.4e-10 40.8 0.0 1.4e-09 38.3 0.0 2.1 1 1 0 1 1 1 1 Shikimate kinase AAA_18 PF13238.6 KKK20620.1 - 1.4e-09 38.5 0.0 7e-09 36.3 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KKK20620.1 - 1.6e-09 38.1 0.0 2.1e-09 37.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain Cytidylate_kin PF02224.18 KKK20620.1 - 5.5e-05 23.0 0.0 9.1e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Cytidylate kinase dNK PF01712.19 KKK20620.1 - 6.2e-05 22.9 0.0 0.091 12.6 0.0 2.1 2 0 0 2 2 2 2 Deoxynucleoside kinase AAA_17 PF13207.6 KKK20620.1 - 0.00094 19.6 0.1 0.011 16.2 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KKK20620.1 - 0.002 18.4 0.0 0.0032 17.7 0.0 1.5 1 1 0 1 1 1 1 AAA domain Staph_opine_DH PF10100.9 KKK20620.1 - 0.016 13.9 0.0 0.021 13.5 0.0 1.1 1 0 0 1 1 1 0 Staphylopine dehydrogenase AAA_16 PF13191.6 KKK20620.1 - 0.017 15.5 0.0 0.028 14.8 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 KKK20620.1 - 0.021 14.5 0.0 0.075 12.8 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain Rad17 PF03215.15 KKK20620.1 - 0.023 14.6 0.0 0.038 13.9 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain CoaE PF01121.20 KKK20620.1 - 0.029 14.0 0.0 0.054 13.2 0.0 1.4 1 0 0 1 1 1 0 Dephospho-CoA kinase APS_kinase PF01583.20 KKK20620.1 - 0.064 13.1 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_30 PF13604.6 KKK20620.1 - 0.092 12.5 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KKK20620.1 - 0.11 12.9 0.0 0.2 12.0 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA PF00004.29 KKK20620.1 - 0.16 12.4 0.0 0.29 11.6 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Vps26 PF03643.15 KKK20621.1 - 1.2e-129 431.2 0.5 1.4e-129 431.0 0.5 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.29 KKK20621.1 - 0.00018 21.6 0.2 0.5 10.4 0.1 3.0 3 0 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 KKK20621.1 - 0.0029 18.1 0.2 0.047 14.1 0.0 2.6 2 1 1 3 3 3 1 Arrestin (or S-antigen), C-terminal domain 2-oxoacid_dh PF00198.23 KKK20622.1 - 5.9e-77 258.2 0.0 8.5e-77 257.7 0.0 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 KKK20622.1 - 1.8e-13 50.1 0.0 3.4e-13 49.2 0.0 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 KKK20622.1 - 1.1e-12 48.0 0.3 4.8e-12 46.0 0.1 2.2 2 0 0 2 2 2 1 e3 binding domain PI-PLC-X PF00388.19 KKK20623.1 - 9.4e-10 38.2 0.0 1.5e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain DUF3435 PF11917.8 KKK20624.1 - 1.2e-127 426.4 0.2 1.8e-105 353.3 0.0 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF3435) zf-C2H2_11 PF16622.5 KKK20624.1 - 0.024 14.4 1.6 0.073 12.9 1.6 1.8 1 0 0 1 1 1 0 zinc-finger C2H2-type zf-C2H2_4 PF13894.6 KKK20624.1 - 0.16 12.9 3.8 0.53 11.3 3.8 1.9 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2 PF00096.26 KKK20624.1 - 0.66 10.5 4.1 1.7 9.2 4.1 1.8 1 0 0 1 1 1 0 Zinc finger, C2H2 type HNH_2 PF13391.6 KKK20625.1 - 1.6e-15 56.9 0.1 4.3e-15 55.6 0.0 1.8 2 0 0 2 2 2 1 HNH endonuclease APH PF01636.23 KKK20627.1 - 8.7e-15 55.3 0.0 2e-14 54.1 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family PHD PF00628.29 KKK20628.1 - 3.1e-08 33.4 9.8 3.1e-08 33.4 9.8 1.9 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.6 KKK20628.1 - 0.12 12.0 9.7 0.029 13.9 5.6 2.0 2 0 0 2 2 2 0 PHD-finger C1_2 PF03107.16 KKK20628.1 - 6.7 7.1 6.8 0.94 9.8 2.0 2.0 2 0 0 2 2 2 0 C1 domain zf-RING_9 PF13901.6 KKK20628.1 - 7.2 6.5 9.1 11 5.9 9.1 1.3 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon Rcd1 PF04078.13 KKK20629.1 - 3.7e-126 419.7 3.2 4.5e-126 419.4 3.2 1.1 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like ARS2 PF04959.13 KKK20629.1 - 3.1 8.1 8.0 4.7 7.5 8.0 1.2 1 0 0 1 1 1 0 Arsenite-resistance protein 2 Med15 PF09606.10 KKK20629.1 - 4.1 6.0 19.9 4.8 5.7 19.9 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal TFIIA PF03153.13 KKK20629.1 - 4.9 7.0 16.9 6.3 6.7 16.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Complex1_LYR PF05347.15 KKK20630.1 - 5.6e-15 55.1 1.7 7.7e-15 54.7 0.0 2.1 2 1 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KKK20630.1 - 3.2e-05 24.6 2.5 6e-05 23.7 1.2 2.2 2 1 0 2 2 2 1 Complex1_LYR-like Complex1_LYR_1 PF13232.6 KKK20630.1 - 0.031 14.9 0.4 0.1 13.2 0.0 2.0 2 0 0 2 2 2 0 Complex1_LYR-like SIR2 PF02146.17 KKK20631.1 - 4e-60 202.7 0.0 6e-60 202.2 0.0 1.3 1 0 0 1 1 1 1 Sir2 family DUF592 PF04574.13 KKK20631.1 - 0.00037 20.3 0.0 0.00073 19.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF592) TPP_enzyme_M PF00205.22 KKK20631.1 - 0.0092 15.7 0.1 2.7 7.7 0.0 2.4 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain FYDLN_acid PF09538.10 KKK20631.1 - 6.6 7.5 7.2 19 6.0 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) TPR_19 PF14559.6 KKK20632.1 - 5.2e-12 46.1 6.6 2.6e-05 24.6 0.3 3.8 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 KKK20632.1 - 3.4e-11 43.6 4.4 0.00012 22.7 0.2 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 KKK20632.1 - 2.7e-09 37.1 8.9 0.046 14.6 0.2 4.8 3 2 1 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 KKK20632.1 - 5.3e-09 36.2 0.8 5.6e-05 23.4 0.0 3.6 3 1 1 4 4 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KKK20632.1 - 4.2e-08 32.7 4.3 0.011 15.8 0.0 5.7 7 0 0 7 7 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KKK20632.1 - 7.8e-06 26.0 0.0 0.16 12.2 0.0 3.0 3 0 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 KKK20632.1 - 1.3e-05 25.0 1.1 0.044 14.0 0.0 4.8 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_MalT PF17874.1 KKK20632.1 - 2.9e-05 23.6 0.9 0.017 14.5 0.0 2.4 2 0 0 2 2 2 2 MalT-like TPR region TPR_10 PF13374.6 KKK20632.1 - 0.00024 20.9 0.8 7.7 6.5 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 KKK20632.1 - 0.00035 20.7 0.8 2.7 8.6 0.0 4.8 5 1 0 5 5 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 KKK20632.1 - 0.00037 20.2 3.1 0.057 13.3 0.0 4.4 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_6 PF13174.6 KKK20632.1 - 0.00048 20.6 4.1 0.24 12.1 0.1 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_9 PF13371.6 KKK20632.1 - 0.005 17.0 6.4 12 6.1 0.1 4.3 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_15 PF13429.6 KKK20632.1 - 0.01 15.1 6.3 0.017 14.3 0.1 3.5 3 2 1 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 KKK20632.1 - 0.016 14.9 0.0 0.16 11.7 0.0 2.7 3 0 0 3 3 3 0 TPR repeat YfiO PF13525.6 KKK20632.1 - 0.029 14.1 0.1 6.3 6.5 0.0 2.5 2 0 0 2 2 2 0 Outer membrane lipoprotein Alkyl_sulf_dimr PF14863.6 KKK20632.1 - 0.1 13.1 0.2 0.51 10.8 0.0 2.2 3 0 0 3 3 3 0 Alkyl sulfatase dimerisation Ribosomal_L2_C PF03947.18 KKK20633.1 - 1e-51 174.4 1.9 1.5e-50 170.6 1.8 2.4 2 1 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 KKK20633.1 - 2.7e-25 88.1 0.9 1e-24 86.2 0.3 2.3 3 0 0 3 3 3 1 Ribosomal Proteins L2, RNA binding domain PAS PF00989.25 KKK20633.1 - 0.15 12.1 0.1 0.29 11.1 0.1 1.4 1 0 0 1 1 1 0 PAS fold Fungal_trans PF04082.18 KKK20634.1 - 6.8e-20 71.2 0.0 1.4e-19 70.2 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK20634.1 - 1.3e-09 38.0 12.0 2.5e-09 37.1 12.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF655 PF04919.12 KKK20634.1 - 0.13 12.2 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF655) UPF0020 PF01170.18 KKK20635.1 - 5.9e-08 32.6 0.1 0.0015 18.3 0.1 2.4 1 1 1 2 2 2 2 Putative RNA methylase family UPF0020 Ribonuc_P_40 PF08584.11 KKK20636.1 - 4.1e-70 236.3 0.0 5.1e-70 236.0 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease P 40kDa (Rpp40) subunit WD40 PF00400.32 KKK20637.1 - 3.8e-24 84.5 16.6 4.8e-07 30.4 0.1 7.0 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKK20637.1 - 7.3e-20 71.1 0.0 0.0004 20.6 0.0 6.2 2 2 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 KKK20637.1 - 6.2e-09 34.9 0.0 2.1e-05 23.3 0.0 2.1 2 0 0 2 2 2 2 Cytochrome D1 heme domain eIF2A PF08662.11 KKK20637.1 - 5.7e-05 23.1 0.0 0.48 10.3 0.0 2.9 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A PALB2_WD40 PF16756.5 KKK20637.1 - 0.00089 18.3 0.0 0.0017 17.3 0.0 1.4 1 0 0 1 1 1 1 Partner and localizer of BRCA2 WD40 domain Nup160 PF11715.8 KKK20637.1 - 0.003 16.3 0.3 0.45 9.1 0.1 2.1 1 1 1 2 2 2 2 Nucleoporin Nup120/160 MFS_1 PF07690.16 KKK20638.1 - 1.2e-22 80.3 49.0 1.4e-22 80.2 48.1 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 KKK20638.1 - 0.044 12.6 0.3 0.044 12.6 0.3 2.9 2 1 1 3 3 3 0 MFS_1 like family Methyltransf_4 PF02390.17 KKK20639.1 - 6.9e-35 120.0 0.0 9.6e-30 103.3 0.0 2.9 3 0 0 3 3 3 2 Putative methyltransferase ESSS PF10183.9 KKK20640.1 - 1.1e-18 67.4 0.0 1.2e-18 67.3 0.0 1.1 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Dna2 PF08696.11 KKK20641.1 - 8.3e-68 228.2 1.0 1.7e-67 227.2 1.0 1.5 1 0 0 1 1 1 1 DNA replication factor Dna2 AAA_12 PF13087.6 KKK20641.1 - 7.3e-53 179.2 0.0 1.2e-52 178.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KKK20641.1 - 2.4e-31 109.5 6.4 1.4e-17 64.4 0.0 3.5 3 1 1 4 4 4 2 AAA domain AAA_30 PF13604.6 KKK20641.1 - 8.9e-15 54.9 0.0 1.6e-14 54.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KKK20641.1 - 6.7e-13 49.2 0.4 1.9e-12 47.7 0.2 2.0 2 0 0 2 2 1 1 AAA domain Cas_Cas4 PF01930.17 KKK20641.1 - 6e-08 32.9 0.1 2e-07 31.3 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function DUF83 PDDEXK_1 PF12705.7 KKK20641.1 - 2.9e-07 30.7 0.0 7.9e-07 29.2 0.0 1.8 1 1 0 1 1 1 1 PD-(D/E)XK nuclease superfamily Viral_helicase1 PF01443.18 KKK20641.1 - 4.4e-07 29.9 0.1 0.43 10.3 0.0 3.6 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.14 KKK20641.1 - 8.4e-05 22.5 0.0 0.00025 21.0 0.0 1.9 1 0 0 1 1 1 1 Helicase UvrD-helicase PF00580.21 KKK20641.1 - 0.00076 19.1 1.8 0.0015 18.2 0.1 2.2 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain SRP54 PF00448.22 KKK20641.1 - 0.0017 18.0 0.1 0.0035 17.0 0.1 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_16 PF13191.6 KKK20641.1 - 0.0033 17.8 0.0 0.0096 16.3 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain PIF1 PF05970.14 KKK20641.1 - 0.0083 15.3 0.2 0.24 10.5 0.0 2.5 3 0 0 3 3 3 1 PIF1-like helicase CbiA PF01656.23 KKK20641.1 - 0.0099 15.9 0.3 0.033 14.3 0.3 1.8 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MobB PF03205.14 KKK20641.1 - 0.01 15.7 0.1 0.024 14.5 0.1 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ResIII PF04851.15 KKK20641.1 - 0.01 15.8 0.0 0.028 14.4 0.0 1.8 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_7 PF12775.7 KKK20641.1 - 0.045 13.3 0.1 0.1 12.1 0.1 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF87 PF01935.17 KKK20641.1 - 0.059 13.5 0.2 0.18 11.9 0.2 1.8 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_18 PF13238.6 KKK20641.1 - 0.068 13.7 0.0 0.6 10.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 KKK20641.1 - 0.1 13.0 0.6 0.36 11.3 0.0 2.3 3 0 0 3 3 1 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KKK20641.1 - 0.11 12.5 0.0 0.39 10.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) MeaB PF03308.16 KKK20641.1 - 0.13 11.2 0.1 0.31 10.0 0.1 1.5 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_25 PF13481.6 KKK20641.1 - 0.15 11.7 0.0 0.34 10.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 KKK20641.1 - 0.18 11.7 0.2 0.6 10.0 0.2 1.8 1 0 0 1 1 1 0 NTPase RNB PF00773.19 KKK20642.1 - 3.5e-98 328.9 0.4 6.9e-98 328.0 0.1 1.6 2 0 0 2 2 2 1 RNB domain Rrp44_CSD1 PF17216.3 KKK20642.1 - 7.5e-31 106.8 0.0 1.7e-30 105.7 0.0 1.6 1 0 0 1 1 1 1 Rrp44-like cold shock domain Rrp44_S1 PF17215.3 KKK20642.1 - 5e-28 96.9 1.3 1.1e-27 95.7 1.3 1.6 1 0 0 1 1 1 1 S1 domain OB_Dis3 PF17849.1 KKK20642.1 - 6.6e-20 70.9 0.0 1.6e-19 69.7 0.0 1.7 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) PIN_4 PF13638.6 KKK20642.1 - 5e-09 36.5 0.3 1.1e-08 35.4 0.3 1.6 1 0 0 1 1 1 1 PIN domain CSD2 PF17876.1 KKK20642.1 - 1.3e-08 34.9 0.4 2.3e-05 24.4 0.0 3.2 2 1 1 3 3 3 2 Cold shock domain CN_hydrolase PF00795.22 KKK20643.1 - 4.8e-53 180.1 0.0 5.6e-53 179.9 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase APH PF01636.23 KKK20644.1 - 7.5e-20 71.9 0.0 9.9e-20 71.5 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KKK20644.1 - 0.0011 18.6 0.0 0.0019 17.8 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 KKK20644.1 - 0.052 13.1 0.0 0.65 9.6 0.0 2.1 2 0 0 2 2 2 0 RIO1 family Fic PF02661.18 KKK20645.1 - 1e-10 42.4 0.3 2.1e-10 41.4 0.3 1.5 1 1 0 1 1 1 1 Fic/DOC family Adeno_PIX PF03955.14 KKK20654.1 - 1.9 8.7 10.2 4.5 7.5 10.2 1.5 1 0 0 1 1 1 0 Adenovirus hexon-associated protein (IX) TAF4 PF05236.14 KKK20654.1 - 2 8.1 14.2 2.9 7.6 11.7 2.2 2 0 0 2 2 2 0 Transcription initiation factor TFIID component TAF4 family K_channel_TID PF07941.11 KKK20654.1 - 4.1 7.9 16.9 15 6.1 16.9 2.0 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain RskA PF10099.9 KKK20654.1 - 7.7 6.8 16.7 0.73 10.1 11.3 2.1 3 0 0 3 3 3 0 Anti-sigma-K factor rskA INSIG PF07281.12 KKK20655.1 - 9.1e-77 257.5 0.9 1.2e-76 257.1 0.9 1.2 1 0 0 1 1 1 1 Insulin-induced protein (INSIG) Bromodomain PF00439.25 KKK20656.1 - 1.9e-25 88.8 0.2 3.3e-25 87.9 0.2 1.4 1 0 0 1 1 1 1 Bromodomain Acetyltransf_1 PF00583.25 KKK20656.1 - 2.1e-07 31.2 0.0 3.9e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KKK20656.1 - 3.1e-07 30.4 0.1 7e-07 29.2 0.1 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KKK20656.1 - 0.00051 20.4 0.3 0.001 19.4 0.1 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain DEAD PF00270.29 KKK20657.1 - 5.5e-48 163.1 0.0 1.2e-47 161.9 0.0 1.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KKK20657.1 - 1.7e-31 108.8 0.0 4.4e-31 107.5 0.0 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KKK20657.1 - 0.0046 17.0 0.0 0.0083 16.1 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 KKK20657.1 - 0.11 11.8 0.1 0.19 11.1 0.1 1.2 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit ERCC3_RAD25_C PF16203.5 KKK20657.1 - 0.11 11.7 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase Ribosomal_S13 PF00416.22 KKK20658.1 - 7.5e-18 65.2 0.2 1.3e-15 58.0 0.2 2.0 1 1 0 1 1 1 1 Ribosomal protein S13/S18 EMP24_GP25L PF01105.24 KKK20659.1 - 8.3e-50 169.2 0.1 9.7e-50 169.0 0.1 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF2721 PF11026.8 KKK20659.1 - 0.43 10.5 3.5 0.19 11.6 0.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) SANT_DAMP1_like PF16282.5 KKK20660.1 - 8e-31 106.1 2.6 1.4e-30 105.3 2.6 1.4 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 DMAP1 PF05499.12 KKK20660.1 - 8.7e-06 25.7 8.5 2.1e-05 24.5 3.1 2.9 2 1 1 3 3 3 1 DNA methyltransferase 1-associated protein 1 (DMAP1) Myb_DNA-binding PF00249.31 KKK20660.1 - 0.055 13.7 0.0 0.2 11.9 0.0 2.1 1 0 0 1 1 1 0 Myb-like DNA-binding domain DUF1180 PF06679.12 KKK20660.1 - 1.1 9.7 16.6 0.95 9.9 3.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) Blt1_C PF17183.4 KKK20661.1 - 0.25 11.0 0.8 1.4 8.6 0.1 2.1 2 0 0 2 2 2 0 Get5 carboxyl domain HATPase_c PF02518.26 KKK20662.1 - 1.2e-21 77.3 0.0 2.9e-21 76.1 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KKK20662.1 - 2.5e-16 59.8 0.3 0.00017 21.7 0.0 3.6 3 0 0 3 3 3 3 Response regulator receiver domain HisKA PF00512.25 KKK20662.1 - 5e-06 26.5 0.0 1.7e-05 24.7 0.0 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 KKK20662.1 - 0.039 13.8 0.0 0.11 12.4 0.0 1.7 2 0 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 KKK20662.1 - 0.14 12.1 0.0 0.43 10.5 0.0 1.8 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain Ufd2P_core PF10408.9 KKK20663.1 - 2.1e-221 736.9 9.6 2.6e-221 736.6 9.6 1.1 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.15 KKK20663.1 - 5.8e-27 93.7 3.6 5.9e-27 93.6 1.0 2.5 2 0 0 2 2 2 1 U-box domain Endonuc-MspI PF09208.10 KKK20663.1 - 0.066 12.6 0.1 0.12 11.8 0.1 1.3 1 0 0 1 1 1 0 Restriction endonuclease MspI Focal_AT PF03623.13 KKK20663.1 - 0.14 12.2 0.0 0.39 10.7 0.0 1.7 1 0 0 1 1 1 0 Focal adhesion targeting region DUF1977 PF09320.11 KKK20664.1 - 2.9e-32 111.0 0.0 5.3e-32 110.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) DnaJ PF00226.31 KKK20664.1 - 8e-22 77.1 0.1 1.6e-21 76.2 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain Meth_synt_2 PF01717.18 KKK20665.1 - 5.7e-153 508.9 0.0 1.3e-149 497.9 0.0 2.3 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 KKK20665.1 - 8.6e-119 396.7 0.0 4.3e-111 371.4 0.0 3.0 3 0 0 3 3 3 2 Cobalamin-independent synthase, N-terminal domain SHOCT PF09851.9 KKK20665.1 - 0.26 11.1 1.4 0.48 10.2 0.2 2.2 2 0 0 2 2 2 0 Short C-terminal domain Steroid_dh PF02544.16 KKK20666.1 - 4.4e-15 56.0 0.2 0.00011 22.3 0.0 4.0 4 1 0 4 4 4 3 3-oxo-5-alpha-steroid 4-dehydrogenase DUF3446 PF11928.8 KKK20666.1 - 0.00025 21.3 5.9 0.00025 21.3 5.9 2.3 2 0 0 2 2 2 1 Early growth response N-terminal domain DUF1295 PF06966.12 KKK20666.1 - 0.014 14.9 0.0 0.039 13.5 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1295) SR-25 PF10500.9 KKK20666.1 - 0.02 14.5 14.6 0.028 14.0 14.6 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein TMEM214 PF10151.9 KKK20666.1 - 0.31 9.5 0.8 0.46 8.9 0.8 1.1 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator DUF755 PF05501.11 KKK20666.1 - 4.1 7.7 15.3 7.9 6.8 15.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF755) RCDG1 PF15725.5 KKK20666.1 - 6.9 7.2 14.0 1.2 9.6 8.7 2.4 3 0 0 3 3 3 0 Renal cancer differentiation gene 1 protein Aim19 PF10315.9 KKK20667.1 - 1.4e-05 25.4 0.2 1.7e-05 25.1 0.2 1.3 1 0 0 1 1 1 1 Altered inheritance of mitochondria protein 19 Ank_2 PF12796.7 KKK20668.1 - 1.2e-18 67.4 0.0 1.6e-17 63.9 0.0 2.9 3 1 0 3 3 3 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KKK20668.1 - 9e-14 50.3 0.0 0.00072 19.8 0.0 4.3 3 0 0 3 3 3 3 Ankyrin repeat Ank PF00023.30 KKK20668.1 - 4.6e-13 49.0 0.0 0.00083 19.7 0.0 3.9 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 KKK20668.1 - 2.7e-11 43.5 0.0 0.042 14.2 0.0 3.8 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 KKK20668.1 - 3.5e-09 37.0 0.0 7.8e-05 23.2 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeats (many copies) AAA_22 PF13401.6 KKK20668.1 - 0.00011 22.5 0.0 0.0082 16.4 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KKK20668.1 - 0.00012 22.6 0.1 0.00065 20.1 0.0 2.4 2 1 0 2 2 2 1 AAA ATPase domain NACHT PF05729.12 KKK20668.1 - 0.018 14.9 0.0 0.048 13.6 0.0 1.7 1 0 0 1 1 1 0 NACHT domain AAA_14 PF13173.6 KKK20668.1 - 0.057 13.4 0.0 0.18 11.8 0.0 2.0 1 0 0 1 1 1 0 AAA domain Myb_DNA-bind_6 PF13921.6 KKK20669.1 - 1.4e-16 60.4 0.2 1.4e-16 60.4 0.2 2.1 2 0 0 2 2 2 1 Myb-like DNA-binding domain HSA PF07529.13 KKK20669.1 - 2e-13 50.4 0.2 2e-13 50.4 0.2 4.0 4 0 0 4 4 4 1 HSA Myb_DNA-binding PF00249.31 KKK20669.1 - 0.0004 20.5 1.7 0.00081 19.5 0.4 2.2 2 0 0 2 2 2 1 Myb-like DNA-binding domain G-patch_2 PF12656.7 KKK20670.1 - 2.1e-24 85.4 1.2 4e-24 84.5 0.1 2.2 2 0 0 2 2 2 1 G-patch domain G-patch PF01585.23 KKK20670.1 - 0.00041 20.2 0.2 0.0011 18.8 0.2 1.7 1 0 0 1 1 1 1 G-patch domain MCRS_N PF13325.6 KKK20670.1 - 0.051 13.6 1.7 0.09 12.8 1.7 1.3 1 0 0 1 1 1 0 N-terminal region of micro-spherule protein WD40 PF00400.32 KKK20671.1 - 2.1e-50 167.6 22.1 9.3e-07 29.5 0.0 13.4 12 4 0 12 12 12 9 WD domain, G-beta repeat Utp13 PF08625.11 KKK20671.1 - 2.1e-48 163.8 0.1 3.5e-48 163.1 0.1 1.3 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain ANAPC4_WD40 PF12894.7 KKK20671.1 - 1.4e-13 51.0 0.4 0.19 12.0 0.0 6.8 5 3 1 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KKK20671.1 - 3.7e-07 29.2 3.7 0.44 9.1 0.0 5.8 3 3 3 6 6 6 4 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KKK20671.1 - 0.0038 16.2 0.2 4 6.3 0.0 4.4 4 1 1 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 KKK20671.1 - 0.11 11.0 0.2 1.4 7.3 0.0 2.2 2 0 0 2 2 2 0 Cytochrome D1 heme domain Ribosomal_L34 PF00468.17 KKK20673.1 - 9.5e-17 60.7 11.5 1.5e-16 60.1 11.5 1.3 1 0 0 1 1 1 1 Ribosomal protein L34 DUF3381 PF11861.8 KKK20674.1 - 0.011 15.5 8.5 0.014 15.2 8.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) Peptidase_M48_N PF16491.5 KKK20675.1 - 1.5e-65 220.5 6.1 1.5e-65 220.5 6.1 1.8 2 0 0 2 2 2 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M48 PF01435.18 KKK20675.1 - 4.3e-46 157.2 0.7 6.6e-46 156.6 0.0 1.6 2 0 0 2 2 2 1 Peptidase family M48 DUF4538 PF15061.6 KKK20675.1 - 0.033 13.9 1.5 0.033 13.9 1.5 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4538) Peptidase_M56 PF05569.11 KKK20675.1 - 0.076 12.2 1.7 0.13 11.5 0.7 1.8 2 1 0 2 2 2 0 BlaR1 peptidase M56 eIF2_C PF09173.11 KKK20676.1 - 1.4e-34 118.2 0.5 3.1e-34 117.1 0.5 1.6 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.27 KKK20676.1 - 7.6e-22 77.8 0.0 3e-21 75.9 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 KKK20676.1 - 7.3e-12 45.5 0.1 1.9e-11 44.2 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KKK20676.1 - 0.027 14.5 0.0 0.07 13.2 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KKK20676.1 - 0.065 13.1 0.0 0.39 10.6 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase UCH PF00443.29 KKK20677.1 - 1.4e-23 83.7 0.0 4.2e-23 82.2 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 KKK20677.1 - 7.6e-12 45.4 0.1 1.7e-11 44.2 0.1 1.5 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 KKK20677.1 - 0.092 12.3 0.0 0.22 11.1 0.0 1.8 1 1 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase Proteasome PF00227.26 KKK20678.1 - 6.1e-39 133.5 0.0 7.3e-39 133.2 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Sigma54_AID PF00309.20 KKK20678.1 - 0.15 11.9 0.0 0.31 10.9 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 factor, Activator interacting domain (AID) Pro_isomerase PF00160.21 KKK20679.1 - 6.4e-48 163.0 0.2 8.5e-48 162.6 0.2 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Glyco_hydro_71 PF03659.14 KKK20680.1 - 5.7e-129 430.2 7.8 6.6e-129 430.0 7.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 Glyco_hydro_71 PF03659.14 KKK20681.1 - 2.7e-126 421.4 10.2 3.2e-126 421.2 10.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 DUF4434 PF14488.6 KKK20681.1 - 0.036 14.1 0.1 0.066 13.2 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4434) TUG-UBL1 PF11470.8 KKK20682.1 - 2e-24 85.6 0.1 1e-23 83.3 0.0 2.2 2 0 0 2 2 2 1 TUG ubiquitin-like domain UBX PF00789.20 KKK20682.1 - 0.00054 20.1 0.4 0.0026 17.9 0.0 2.2 2 0 0 2 2 2 1 UBX domain RBD PF02196.15 KKK20682.1 - 0.02 15.0 0.2 0.22 11.6 0.0 2.6 3 0 0 3 3 3 0 Raf-like Ras-binding domain Ribosomal_L36e PF01158.18 KKK20683.1 - 8.8e-23 80.4 0.3 1.4e-22 79.7 0.3 1.3 1 0 0 1 1 1 1 Ribosomal protein L36e PT PF04886.12 KKK20683.1 - 0.34 10.5 16.3 0.17 11.5 13.4 2.0 2 0 0 2 2 2 0 PT repeat CRCB PF02537.15 KKK20684.1 - 0.083 13.2 0.1 0.16 12.3 0.1 1.4 1 0 0 1 1 1 0 CrcB-like protein, Camphor Resistance (CrcB) NatB_MDM20 PF09797.9 KKK20685.1 - 7.8e-109 364.1 0.0 1.4e-108 363.2 0.0 1.4 1 0 0 1 1 1 1 N-acetyltransferase B complex (NatB) non catalytic subunit TPR_19 PF14559.6 KKK20685.1 - 0.00029 21.3 0.1 0.00029 21.3 0.1 3.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 KKK20685.1 - 0.035 14.8 2.5 6.5 7.5 1.6 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 KKK20685.1 - 0.098 13.5 3.4 31 5.7 0.1 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF4363 PF14276.6 KKK20685.1 - 1.3 9.1 4.2 4.2 7.5 0.2 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4363) MTCP1 PF08991.10 KKK20686.1 - 0.023 14.9 0.2 0.041 14.1 0.2 1.4 1 0 0 1 1 1 0 Mature-T-Cell Proliferation I type MIEAP PF16026.5 KKK20686.1 - 0.05 13.8 0.1 0.066 13.4 0.1 1.1 1 0 0 1 1 1 0 Mitochondria-eating protein CHCH PF06747.13 KKK20686.1 - 0.17 12.0 5.0 0.24 11.6 1.6 2.4 2 1 0 2 2 2 0 CHCH domain 2OG-FeII_Oxy_3 PF13640.6 KKK20687.1 - 0.09 13.7 0.0 0.17 12.8 0.0 1.4 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily BAR_2 PF10455.9 KKK20687.1 - 0.21 10.7 1.5 0.37 9.9 1.5 1.3 1 0 0 1 1 1 0 Bin/amphiphysin/Rvs domain for vesicular trafficking zf-C3HC4 PF00097.25 KKK20688.1 - 1.9e-08 34.1 4.6 1.9e-08 34.1 4.6 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KKK20688.1 - 7.6e-08 32.6 6.4 7.6e-08 32.6 6.4 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.6 KKK20688.1 - 9.2e-08 31.8 3.0 9.2e-08 31.8 3.0 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KKK20688.1 - 6.2e-07 29.5 7.5 6.2e-07 29.5 7.5 2.2 2 1 1 3 3 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 KKK20688.1 - 1.5e-06 28.0 6.3 1.5e-06 28.0 6.3 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KKK20688.1 - 4e-06 26.7 6.3 1e-05 25.5 6.3 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KKK20688.1 - 6.6e-06 26.0 5.6 6.6e-06 26.0 5.6 2.1 2 0 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KKK20688.1 - 0.0096 15.8 4.6 0.0096 15.8 4.6 2.3 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_6 PF14835.6 KKK20688.1 - 0.01 15.7 3.0 0.01 15.7 3.0 2.0 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-rbx1 PF12678.7 KKK20688.1 - 0.01 16.1 6.0 0.01 16.1 6.0 2.4 2 1 0 2 2 2 0 RING-H2 zinc finger domain Radial_spoke PF04712.12 KKK20688.1 - 0.011 14.8 7.1 0.019 13.9 7.1 1.3 1 0 0 1 1 1 0 Radial spokehead-like protein zf-RING_4 PF14570.6 KKK20688.1 - 0.029 14.2 5.2 0.072 12.9 2.6 2.6 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain DZR PF12773.7 KKK20688.1 - 0.097 12.7 9.5 4.4 7.4 0.1 2.8 2 1 1 3 3 3 0 Double zinc ribbon zf-ANAPC11 PF12861.7 KKK20688.1 - 0.63 10.1 5.9 0.093 12.8 0.9 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 KKK20688.1 - 0.76 9.6 3.3 2.3 8.0 3.3 1.9 1 0 0 1 1 1 0 RING-like zinc finger zinc_ribbon_2 PF13240.6 KKK20688.1 - 3.1 7.6 10.7 12 5.7 0.0 4.0 4 0 0 4 4 4 0 zinc-ribbon domain zf-ribbon_3 PF13248.6 KKK20688.1 - 3.9 7.0 6.8 2.9 7.4 0.9 2.8 2 0 0 2 2 2 0 zinc-ribbon domain WD40 PF00400.32 KKK20689.1 - 1.8e-19 69.7 8.0 2.4e-06 28.2 0.0 6.0 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKK20689.1 - 0.00041 20.6 0.0 0.0043 17.3 0.0 2.5 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KKK20689.1 - 0.033 13.5 0.0 0.055 12.8 0.0 1.4 1 0 0 1 1 1 0 WD40-like domain EHN PF06441.12 KKK20690.1 - 6.7e-35 119.7 1.1 9.5e-34 116.0 0.2 2.4 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 KKK20690.1 - 4.3e-14 52.8 0.0 7.6e-14 52.0 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KKK20690.1 - 3.2e-06 27.9 0.4 3.2e-06 27.9 0.4 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Proteasome PF00227.26 KKK20691.1 - 2.3e-38 131.6 0.0 2.6e-38 131.4 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Peptidase_M16_C PF05193.21 KKK20693.1 - 3.5e-17 63.0 0.0 5e-15 56.0 0.0 2.9 3 0 0 3 3 3 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 KKK20693.1 - 3.2e-06 27.2 0.0 1.2e-05 25.3 0.0 2.0 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) M16C_assoc PF08367.11 KKK20693.1 - 0.63 9.1 6.0 18 4.3 4.4 2.5 2 0 0 2 2 2 0 Peptidase M16C associated Sporozoite_P67 PF05642.11 KKK20693.1 - 2.1 6.3 5.7 2.9 5.8 5.7 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF4600 PF15372.6 KKK20693.1 - 2.7 8.4 5.8 1.2 9.5 0.1 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4600) RRN3 PF05327.11 KKK20693.1 - 6.7 5.1 6.7 10 4.5 6.7 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Astro_capsid_p PF12226.8 KKK20693.1 - 8 5.5 11.2 12 4.9 11.2 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein NLE PF08154.12 KKK20694.1 - 4e-19 68.9 0.1 1.4e-18 67.2 0.1 2.0 1 0 0 1 1 1 1 NLE (NUC135) domain WD40 PF00400.32 KKK20694.1 - 2.7e-18 66.0 23.8 6.4e-06 26.8 0.3 7.3 7 0 0 7 7 7 5 WD domain, G-beta repeat Zw10 PF06248.13 KKK20694.1 - 1.2e-11 43.9 0.9 2.4e-11 42.9 0.9 1.4 1 0 0 1 1 1 1 Centromere/kinetochore Zw10 Dsl1_C PF11989.8 KKK20694.1 - 6.2e-08 32.6 0.2 1.5e-07 31.4 0.2 1.6 1 0 0 1 1 1 1 Retrograde transport protein Dsl1 C terminal TMF_TATA_bd PF12325.8 KKK20694.1 - 0.57 10.4 2.9 1.2 9.4 1.4 2.4 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Seryl_tRNA_N PF02403.22 KKK20694.1 - 0.87 9.8 5.1 0.25 11.6 1.0 2.2 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain GTP_EFTU PF00009.27 KKK20698.1 - 4.6e-14 52.4 0.0 4.6e-14 52.4 0.0 1.0 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 KKK20698.1 - 0.13 11.7 0.0 0.14 11.6 0.0 1.1 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Pkinase PF00069.25 KKK20699.1 - 2.1e-64 217.4 0.0 2.5e-64 217.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK20699.1 - 2.8e-36 125.2 0.0 3.7e-36 124.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KKK20699.1 - 1.9e-07 30.7 0.0 3e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KKK20699.1 - 8.1e-05 21.6 0.0 0.00012 21.0 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 KKK20699.1 - 0.0064 16.1 0.0 0.96 9.0 0.0 2.2 1 1 1 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 KKK20699.1 - 0.13 11.6 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 KKK20699.1 - 0.17 10.9 0.0 0.25 10.4 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 FAM75 PF14650.6 KKK20699.1 - 2.8 7.4 13.7 4.3 6.8 13.7 1.2 1 0 0 1 1 1 0 FAM75 family Prp18 PF02840.15 KKK20722.1 - 8.6e-57 191.2 0.3 8.6e-57 191.2 0.3 2.0 2 1 0 2 2 2 1 Prp18 domain PRP4 PF08799.11 KKK20722.1 - 6.1e-10 38.5 7.4 6.1e-10 38.5 7.4 3.3 3 0 0 3 3 3 1 pre-mRNA processing factor 4 (PRP4) like CREPT PF16566.5 KKK20722.1 - 0.27 11.4 9.4 0.84 9.8 9.4 1.8 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour TFIIA PF03153.13 KKK20722.1 - 2.4 8.1 15.1 4.6 7.1 15.1 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit V_ATPase_I PF01496.19 KKK20722.1 - 7.1 4.4 10.7 14 3.4 10.7 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Pyr_redox_3 PF13738.6 KKK20723.1 - 0.00015 21.2 0.0 0.0011 18.4 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 KKK20724.1 - 9.3e-49 165.2 0.0 1.3e-48 164.7 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KKK20724.1 - 1.5e-29 102.3 0.0 1.8e-29 102.1 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AdoHcyase_NAD PF00670.21 KKK20724.1 - 0.054 13.6 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain GST_N PF02798.20 KKK20725.1 - 2.1e-13 50.4 0.0 4.4e-13 49.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KKK20725.1 - 3.1e-10 40.3 0.0 5.7e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KKK20725.1 - 1.8e-09 37.8 0.0 3.3e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KKK20725.1 - 9.5e-09 35.4 0.0 1.7e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KKK20725.1 - 6.1e-06 26.2 0.0 1.5e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KKK20725.1 - 9e-05 22.6 0.0 0.00015 21.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 KKK20725.1 - 0.00064 20.3 0.1 0.0018 18.9 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain NDUF_B4 PF07225.12 KKK20726.1 - 5.6e-06 26.3 0.0 6.3e-06 26.1 0.0 1.0 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) BCCT PF02028.17 KKK20726.1 - 0.054 11.9 0.1 0.057 11.8 0.1 1.0 1 0 0 1 1 1 0 BCCT, betaine/carnitine/choline family transporter MitoNEET_N PF10660.9 KKK20726.1 - 0.099 12.7 0.2 0.13 12.3 0.2 1.2 1 0 0 1 1 1 0 Iron-containing outer mitochondrial membrane protein N-terminus SAP18 PF06487.12 KKK20727.1 - 7.8e-52 175.2 0.0 9.4e-52 174.9 0.0 1.1 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) Use1 PF09753.9 KKK20728.1 - 3.4e-09 36.8 8.6 1.9e-08 34.4 8.6 2.2 1 1 0 1 1 1 1 Membrane fusion protein Use1 GldM_N PF12081.8 KKK20728.1 - 0.058 13.5 0.6 0.14 12.2 0.0 1.8 2 0 0 2 2 2 0 GldM N-terminal domain Sin3_corepress PF08295.12 KKK20728.1 - 0.41 10.8 2.2 2.8 8.1 0.2 2.8 2 1 1 3 3 3 0 Sin3 family co-repressor Pes-10 PF07149.11 KKK20728.1 - 0.77 8.8 6.0 1.2 8.1 6.0 1.2 1 0 0 1 1 1 0 Pes-10 DUF1664 PF07889.12 KKK20728.1 - 1.9 8.5 4.1 12 5.9 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) XRCC4 PF06632.12 KKK20728.1 - 2.3 7.0 10.6 4.3 6.1 10.1 1.7 1 1 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 Fzo_mitofusin PF04799.13 KKK20728.1 - 3.5 7.1 5.3 5.6 6.5 1.4 2.3 2 0 0 2 2 2 0 fzo-like conserved region Pneumo_att_G PF05539.11 KKK20728.1 - 7.5 6.0 20.6 11 5.4 20.6 1.3 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G AMP-binding PF00501.28 KKK20729.1 - 3.9e-78 262.9 0.0 1.8e-77 260.7 0.0 1.8 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KKK20729.1 - 1.9e-15 57.6 0.2 4.5e-15 56.4 0.0 1.8 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain IGPS PF00218.21 KKK20731.1 - 4.3e-98 327.5 0.0 1e-97 326.3 0.0 1.6 2 0 0 2 2 2 1 Indole-3-glycerol phosphate synthase PRAI PF00697.22 KKK20731.1 - 1.4e-55 188.1 0.0 1.1e-53 181.9 0.0 2.7 2 1 1 3 3 3 2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase GATase PF00117.28 KKK20731.1 - 4.7e-49 166.7 0.0 7.8e-49 166.0 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I QRPTase_C PF01729.19 KKK20731.1 - 0.00052 19.8 0.1 0.0055 16.5 0.0 2.7 3 0 0 3 3 3 1 Quinolinate phosphoribosyl transferase, C-terminal domain Peptidase_C26 PF07722.13 KKK20731.1 - 0.0014 18.4 1.3 0.012 15.4 1.3 2.1 1 1 0 1 1 1 1 Peptidase C26 His_biosynth PF00977.21 KKK20731.1 - 0.013 14.9 0.2 0.048 13.1 0.0 2.0 2 0 0 2 2 2 0 Histidine biosynthesis protein NanE PF04131.14 KKK20731.1 - 0.021 14.0 0.4 0.086 12.0 0.0 2.2 3 0 0 3 3 3 0 Putative N-acetylmannosamine-6-phosphate epimerase Nup188_C PF18378.1 KKK20732.1 - 2.4e-147 490.6 0.1 4.6e-147 489.7 0.1 1.5 1 0 0 1 1 1 1 Nuclear pore protein NUP188 C-terminal domain Nup188 PF10487.9 KKK20732.1 - 1.9e-82 277.6 0.0 5.6e-82 276.1 0.0 1.7 1 1 0 1 1 1 1 Nucleoporin subcomplex protein binding to Pom34 T2SSF PF00482.23 KKK20732.1 - 0.1 12.5 0.1 0.27 11.2 0.1 1.7 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F Brix PF04427.18 KKK20733.1 - 1.7e-30 106.6 0.0 2.2e-30 106.2 0.0 1.1 1 0 0 1 1 1 1 Brix domain PTCB-BRCT PF12738.7 KKK20734.1 - 2.1e-09 37.2 0.3 3.2e-09 36.6 0.3 1.3 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.26 KKK20734.1 - 1.2e-07 32.0 0.1 2.1e-07 31.2 0.1 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 KKK20734.1 - 8.8e-06 26.0 0.0 1.5e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain WGR PF05406.15 KKK20734.1 - 0.02 14.9 0.0 0.033 14.3 0.0 1.3 1 0 0 1 1 1 0 WGR domain UPF1_Zn_bind PF09416.10 KKK20735.1 - 1.2e-72 242.8 1.6 3.5e-72 241.4 1.4 1.9 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.6 KKK20735.1 - 5.4e-60 202.4 0.0 8.3e-60 201.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KKK20735.1 - 1.4e-54 185.6 2.3 1.4e-31 110.3 0.2 2.3 1 1 1 2 2 2 2 AAA domain DUF5599 PF18141.1 KKK20735.1 - 2.3e-33 114.3 0.0 4.8e-33 113.3 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF5599) AAA_30 PF13604.6 KKK20735.1 - 1.6e-13 50.9 0.2 2.4e-12 47.0 0.2 2.4 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KKK20735.1 - 3.6e-11 43.6 0.0 2e-10 41.2 0.0 2.2 2 1 0 2 2 2 1 AAA domain ResIII PF04851.15 KKK20735.1 - 1.2e-05 25.4 0.0 2.2e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.18 KKK20735.1 - 8.7e-05 22.4 0.2 0.73 9.5 0.0 2.9 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.14 KKK20735.1 - 0.00059 19.7 0.0 0.0012 18.7 0.0 1.6 1 0 0 1 1 1 1 Helicase PIF1 PF05970.14 KKK20735.1 - 0.0027 17.0 0.1 0.44 9.7 0.0 2.2 2 0 0 2 2 2 1 PIF1-like helicase DUF2075 PF09848.9 KKK20735.1 - 0.0048 16.2 0.2 0.034 13.4 0.0 2.3 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) UvrD-helicase PF00580.21 KKK20735.1 - 0.0085 15.7 0.1 0.059 12.9 0.0 2.2 2 1 0 3 3 3 1 UvrD/REP helicase N-terminal domain DEAD PF00270.29 KKK20735.1 - 0.011 15.5 0.0 0.023 14.5 0.0 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase AAA_10 PF12846.7 KKK20735.1 - 0.026 13.5 0.0 0.044 12.7 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain ATPase PF06745.13 KKK20735.1 - 0.039 13.3 0.0 0.087 12.2 0.0 1.5 1 0 0 1 1 1 0 KaiC AAA_22 PF13401.6 KKK20735.1 - 0.07 13.4 0.1 0.23 11.7 0.1 1.9 1 1 0 1 1 1 0 AAA domain Ribosomal_S27e PF01667.17 KKK20735.1 - 1.1 9.0 3.4 1.4 8.7 0.8 2.3 2 0 0 2 2 2 0 Ribosomal protein S27 zf-RanBP PF00641.18 KKK20735.1 - 4.1 6.8 7.4 0.45 9.9 2.3 2.0 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others zf-C2H2 PF00096.26 KKK20736.1 - 2.6e-06 27.6 15.6 0.12 12.8 0.1 3.9 3 1 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_aberr PF17017.5 KKK20736.1 - 4.6e-06 26.9 0.9 5.9e-06 26.6 0.1 1.6 2 0 0 2 2 2 1 Aberrant zinc-finger Cnn_1N PF07989.11 KKK20736.1 - 0.0049 17.0 0.7 0.097 12.8 0.7 2.4 2 0 0 2 2 2 1 Centrosomin N-terminal motif 1 HAUS-augmin3 PF14932.6 KKK20736.1 - 0.016 14.8 0.0 0.023 14.3 0.0 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 FOXP-CC PF16159.5 KKK20736.1 - 0.022 15.3 2.3 4.6 7.9 0.1 2.9 2 1 1 3 3 3 0 FOXP coiled-coil domain Transpos_assoc PF13963.6 KKK20736.1 - 0.03 14.7 0.5 0.54 10.6 0.1 2.3 2 0 0 2 2 2 0 Transposase-associated domain CENP-F_leu_zip PF10473.9 KKK20736.1 - 0.035 14.1 0.3 0.075 13.1 0.3 1.4 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 zf-C2H2_4 PF13894.6 KKK20736.1 - 0.042 14.7 9.0 12 7.0 0.7 3.8 3 1 0 3 3 3 0 C2H2-type zinc finger Trimer_CC PF08954.11 KKK20736.1 - 0.076 12.6 4.9 0.17 11.5 4.9 1.5 1 0 0 1 1 1 0 Trimerisation motif zf-C2HE PF16278.5 KKK20736.1 - 0.2 12.1 1.3 0.52 10.8 1.3 1.7 1 0 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger zf-H2C2_2 PF13465.6 KKK20736.1 - 0.45 11.0 0.2 0.45 11.0 0.2 3.5 3 0 0 3 3 3 0 Zinc-finger double domain MCM_OB PF17207.3 KKK20736.1 - 8.5 6.2 7.0 20 5.1 1.6 2.4 1 1 1 2 2 2 0 MCM OB domain SRP19 PF01922.17 KKK20737.1 - 5.2e-36 123.5 0.0 7.8e-36 122.9 0.0 1.3 1 0 0 1 1 1 1 SRP19 protein Fungal_trans PF04082.18 KKK20738.1 - 7.2e-15 54.7 0.1 1.3e-14 53.9 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK20738.1 - 5.2e-10 39.3 10.5 9.7e-10 38.4 10.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MIP-T3_C PF17749.1 KKK20738.1 - 0.23 11.4 0.5 0.54 10.2 0.1 1.8 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 C-terminal region TCTP PF00838.17 KKK20739.1 - 8.2e-56 188.9 1.0 9.8e-56 188.6 1.0 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein FA_hydroxylase PF04116.13 KKK20740.1 - 7.9e-24 84.5 14.0 1e-23 84.1 12.3 1.9 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily DUF3606 PF12244.8 KKK20740.1 - 0.086 12.8 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3606) DEAD PF00270.29 KKK20742.1 - 4e-35 121.1 0.0 8.1e-17 61.5 0.0 2.4 1 1 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 KKK20742.1 - 9.3e-19 67.8 0.0 2.5e-18 66.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KKK20742.1 - 6.3e-07 29.5 0.2 3.9e-06 27.0 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Nop14 PF04147.12 KKK20742.1 - 0.00021 19.7 13.8 0.00021 19.7 13.8 2.1 2 0 0 2 2 2 1 Nop14-like family SDA1 PF05285.12 KKK20742.1 - 0.0011 18.5 15.2 0.0011 18.5 15.2 2.3 2 0 0 2 2 2 1 SDA1 AAA_22 PF13401.6 KKK20742.1 - 0.09 13.1 0.8 7.2 6.9 0.0 3.3 4 0 0 4 4 4 0 AAA domain Macoilin PF09726.9 KKK20742.1 - 0.53 8.8 33.8 0.091 11.3 8.9 2.2 2 0 0 2 2 2 0 Macoilin family PIGA PF08288.12 KKK20743.1 - 7.2e-47 157.9 4.5 7.3e-47 157.9 1.6 2.2 2 0 0 2 2 2 1 PIGA (GPI anchor biosynthesis) Glyco_transf_4 PF13439.6 KKK20743.1 - 3.2e-28 98.8 0.7 5.1e-28 98.2 0.7 1.3 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 KKK20743.1 - 1.1e-27 96.6 0.0 1.8e-27 96.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KKK20743.1 - 6.9e-24 84.8 0.1 1.4e-23 83.8 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 KKK20743.1 - 1.5e-12 48.3 0.0 2.4e-12 47.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.6 KKK20743.1 - 0.0002 21.4 0.1 0.00046 20.2 0.1 1.6 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.6 KKK20743.1 - 0.0074 16.7 0.0 0.028 14.8 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferases group 1 Arf PF00025.21 KKK20744.1 - 2.1e-40 138.0 0.0 2.4e-26 92.3 0.0 2.3 2 1 0 2 2 2 2 ADP-ribosylation factor family G-alpha PF00503.20 KKK20744.1 - 6.4e-14 51.9 0.0 1.4e-07 31.0 0.0 2.3 2 1 0 2 2 2 2 G-protein alpha subunit Roc PF08477.13 KKK20744.1 - 1.6e-09 38.0 0.0 5.6e-09 36.2 0.0 1.9 2 1 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 KKK20744.1 - 4.9e-07 29.3 0.0 1e-06 28.3 0.0 1.7 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.22 KKK20744.1 - 2.6e-06 27.2 0.0 0.0064 16.1 0.0 2.8 2 1 0 2 2 2 2 Ras family SRPRB PF09439.10 KKK20744.1 - 6.5e-06 25.7 0.0 0.0001 21.8 0.0 2.1 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KKK20744.1 - 4e-05 23.7 0.0 9.7e-05 22.4 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KKK20744.1 - 0.0015 18.1 0.0 0.043 13.3 0.0 2.4 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain TniB PF05621.11 KKK20744.1 - 0.16 11.4 0.0 0.26 10.7 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein FeoB_N PF02421.18 KKK20744.1 - 0.2 11.2 0.0 0.45 10.0 0.0 1.7 1 1 0 1 1 1 0 Ferrous iron transport protein B LSM PF01423.22 KKK20780.1 - 1.1e-08 34.6 0.0 1.4e-08 34.3 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KKK20780.1 - 0.043 14.0 0.0 0.053 13.7 0.0 1.4 1 1 0 1 1 1 0 Ataxin 2 SM domain Metallophos PF00149.28 KKK20781.1 - 8.7e-37 127.6 0.1 1.4e-36 127.0 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KKK20781.1 - 1.1e-16 61.0 0.0 1.9e-16 60.2 0.0 1.4 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain WD40 PF00400.32 KKK20782.1 - 8.5e-12 45.4 4.3 2.1 9.3 0.1 9.0 9 0 0 9 9 9 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKK20782.1 - 4.9e-07 30.0 0.1 0.25 11.7 0.0 5.7 4 2 2 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Lactonase PF10282.9 KKK20782.1 - 0.004 16.5 0.0 0.19 10.9 0.0 2.4 2 0 0 2 2 2 1 Lactonase, 7-bladed beta-propeller PD40 PF07676.12 KKK20782.1 - 0.059 13.3 0.0 1.8 8.6 0.0 2.9 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KKK20782.1 - 0.22 10.5 0.0 3 6.7 0.0 2.6 4 0 0 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Cyclin_N PF00134.23 KKK20783.1 - 4.6e-36 123.4 0.1 1e-35 122.3 0.1 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KKK20783.1 - 4.4e-11 42.9 0.1 9e-11 41.9 0.1 1.5 1 0 0 1 1 1 1 Cyclin, C-terminal domain Memo PF01875.17 KKK20784.1 - 1.8e-64 217.5 0.0 2.2e-64 217.3 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein DUF2207 PF09972.9 KKK20786.1 - 0.082 11.7 5.8 0.11 11.2 0.4 2.7 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) DHHA2 PF02833.14 KKK20787.1 - 1.1e-35 123.0 0.0 1.5e-35 122.4 0.0 1.2 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.20 KKK20787.1 - 8.9e-08 32.3 0.0 2.1e-07 31.1 0.0 1.7 1 1 0 1 1 1 1 DHH family adh_short PF00106.25 KKK20788.1 - 6.8e-23 81.1 0.0 2.3e-21 76.1 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KKK20788.1 - 3.4e-10 39.9 0.0 5.7e-09 35.9 0.0 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KKK20788.1 - 9.9e-09 35.4 0.0 2e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KKK20788.1 - 2.8e-05 23.7 0.0 0.0003 20.3 0.0 2.3 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KKK20788.1 - 0.0022 17.2 0.0 0.0043 16.2 0.0 1.5 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Sacchrp_dh_NADP PF03435.18 KKK20788.1 - 0.021 15.1 0.0 4.9 7.4 0.0 2.2 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Glyco_tran_WecB PF03808.13 KKK20788.1 - 0.034 14.1 0.0 8.5 6.3 0.0 2.2 2 0 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family Phage_holin_4_2 PF04020.13 KKK20789.1 - 0.52 11.0 11.2 0.27 11.9 3.5 2.6 2 0 0 2 2 2 0 Mycobacterial 4 TMS phage holin, superfamily IV WD40 PF00400.32 KKK20790.1 - 4.4e-21 74.8 11.1 0.00016 22.4 0.1 6.8 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKK20790.1 - 9.2e-18 64.3 0.0 6.4e-07 29.6 0.0 5.8 4 2 2 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KKK20790.1 - 6.9e-05 22.8 0.4 0.036 14.0 0.0 2.7 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A HIRA_B PF09453.10 KKK20790.1 - 0.00015 21.5 0.2 0.00062 19.6 0.2 2.1 1 0 0 1 1 1 1 HIRA B motif Ge1_WD40 PF16529.5 KKK20790.1 - 0.0029 16.6 0.1 6 5.7 0.0 4.0 2 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KKK20790.1 - 0.085 12.8 4.9 7.3 6.7 0.2 4.2 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Rad4 PF03835.15 KKK20792.1 - 2.3e-14 53.3 1.8 5.7e-14 52.0 1.8 1.6 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain Transglut_core PF01841.19 KKK20792.1 - 3.7e-13 49.9 1.8 8.7e-13 48.7 1.8 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily DUF2235 PF09994.9 KKK20793.1 - 1e-77 261.4 0.0 1.3e-77 261.0 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) MoCF_biosynth PF00994.24 KKK20794.1 - 1.2e-44 151.4 0.0 6.2e-22 77.8 0.0 2.3 2 0 0 2 2 2 2 Probable molybdopterin binding domain MoeA_N PF03453.17 KKK20794.1 - 2.8e-37 127.9 2.9 5.7e-37 126.9 2.9 1.6 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.15 KKK20794.1 - 7.2e-17 61.3 0.2 1.8e-16 60.0 0.2 1.8 1 0 0 1 1 1 1 MoeA C-terminal region (domain IV) FSH1 PF03959.13 KKK20795.1 - 8.5e-24 84.4 0.0 1.1e-23 84.1 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_1 PF00561.20 KKK20795.1 - 0.011 15.4 0.7 0.19 11.3 0.5 2.4 1 1 0 2 2 2 0 alpha/beta hydrolase fold XPA_C PF05181.12 KKK20796.1 - 1.8e-26 91.8 3.2 3.9e-26 90.8 3.2 1.6 1 0 0 1 1 1 1 XPA protein C-terminus XPA_N PF01286.18 KKK20796.1 - 0.00046 20.2 5.1 0.00046 20.2 5.1 2.1 2 0 0 2 2 2 1 XPA protein N-terminal YhfH PF14149.6 KKK20796.1 - 0.0099 15.8 4.7 0.46 10.5 0.8 2.6 2 0 0 2 2 2 2 YhfH-like protein NTP_transf_5 PF14907.6 KKK20821.1 - 0.17 11.5 0.0 2.1 7.9 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised nucleotidyltransferase Stb3 PF10330.9 KKK20836.1 - 8.9e-39 131.4 0.0 1.4e-38 130.8 0.0 1.3 1 0 0 1 1 1 1 Putative Sin3 binding protein NnrS PF05940.12 KKK20836.1 - 0.27 10.6 0.0 0.36 10.2 0.0 1.1 1 0 0 1 1 1 0 NnrS protein HNH_2 PF13391.6 KKK20837.1 - 2.6e-18 65.9 0.1 7.7e-18 64.4 0.0 1.9 2 0 0 2 2 2 1 HNH endonuclease Glu-tRNAGln PF02686.15 KKK20837.1 - 0.11 12.8 0.1 0.24 11.7 0.1 1.6 1 0 0 1 1 1 0 Glu-tRNAGln amidotransferase C subunit Ifi-6-16 PF06140.13 KKK20843.1 - 3.9e-07 29.9 27.2 3.9e-07 29.9 27.2 1.9 2 1 0 2 2 2 1 Interferon-induced 6-16 family NMO PF03060.15 KKK20844.1 - 7.6e-29 101.1 2.1 1.3e-22 80.6 0.4 2.2 2 0 0 2 2 2 2 Nitronate monooxygenase IMPDH PF00478.25 KKK20844.1 - 3.5e-11 42.7 0.1 2.5e-06 26.8 1.9 2.1 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 KKK20844.1 - 2.2e-06 26.9 1.3 3.7e-06 26.2 1.3 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 KKK20844.1 - 0.0047 16.1 0.4 0.0071 15.5 0.4 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase DHO_dh PF01180.21 KKK20844.1 - 0.022 14.0 0.1 0.033 13.4 0.1 1.2 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase His_biosynth PF00977.21 KKK20844.1 - 0.12 11.9 0.0 0.46 9.9 0.0 1.9 2 0 0 2 2 2 0 Histidine biosynthesis protein Stk19 PF10494.9 KKK20845.1 - 9.2e-89 297.3 0.0 1.1e-88 297.1 0.0 1.1 1 0 0 1 1 1 1 Serine-threonine protein kinase 19 NmrA PF05368.13 KKK20847.1 - 5.4e-39 134.1 0.0 6.4e-39 133.9 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KKK20847.1 - 2.2e-12 47.2 0.0 3.1e-12 46.8 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KKK20847.1 - 5.5e-05 22.7 0.0 7.7e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.18 KKK20847.1 - 0.0086 16.3 0.1 0.051 13.8 0.1 2.0 2 0 0 2 2 2 1 TrkA-N domain 3Beta_HSD PF01073.19 KKK20847.1 - 0.011 14.8 0.0 0.015 14.3 0.0 1.1 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.20 KKK20847.1 - 0.026 14.6 0.1 0.048 13.8 0.1 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus zf-NOSIP PF15906.5 KKK20849.1 - 0.0021 18.2 0.0 0.0039 17.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein Atg14 PF10186.9 KKK20849.1 - 0.01 14.9 8.6 0.019 14.1 8.6 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 FAM76 PF16046.5 KKK20849.1 - 0.08 12.3 0.2 0.08 12.3 0.2 3.0 2 1 0 2 2 2 0 FAM76 protein SnoaL PF07366.12 KKK20850.1 - 0.0002 21.1 0.0 0.00038 20.2 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 KKK20850.1 - 0.00035 21.1 0.0 0.00063 20.4 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like domain FMO-like PF00743.19 KKK20851.1 - 7.2e-13 47.8 0.0 2.3e-11 42.9 0.0 2.1 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KKK20851.1 - 4e-12 46.0 0.0 1.5e-10 40.9 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KKK20851.1 - 3.5e-11 42.9 0.0 2.1e-10 40.3 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KKK20851.1 - 2.6e-05 24.3 0.7 0.00013 22.2 0.0 2.4 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KKK20851.1 - 8.5e-05 21.9 0.8 0.0094 15.2 0.0 2.2 2 0 0 2 2 2 2 Thi4 family K_oxygenase PF13434.6 KKK20851.1 - 0.00024 20.4 0.0 0.0031 16.7 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 KKK20851.1 - 0.00024 21.1 0.6 0.0055 16.7 0.0 3.0 3 1 0 3 3 3 1 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.21 KKK20851.1 - 0.0053 16.1 0.1 0.03 13.6 0.0 2.1 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.7 KKK20851.1 - 0.011 15.2 0.0 0.041 13.2 0.0 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox PF00070.27 KKK20851.1 - 0.044 14.4 0.3 9.5 6.9 0.1 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KKK20851.1 - 0.062 12.9 0.3 11 5.5 0.0 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KKK20851.1 - 0.12 11.5 0.0 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Amino_oxidase PF01593.24 KKK20851.1 - 0.13 11.6 0.0 7.8 5.7 0.0 2.8 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase Fungal_trans PF04082.18 KKK20852.1 - 4.8e-28 97.9 3.5 8e-28 97.2 3.5 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 KKK20852.1 - 8.6e-05 22.8 16.2 0.0071 16.7 0.3 3.2 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KKK20852.1 - 0.019 15.7 14.5 0.15 13.0 0.4 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KKK20852.1 - 1.7 8.7 6.3 0.39 10.8 0.1 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger Methyltransf_25 PF13649.6 KKK20854.1 - 5.3e-15 55.9 0.0 8.1e-14 52.1 0.0 2.7 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_12 PF08242.12 KKK20854.1 - 9.3e-14 52.0 0.0 3.1e-13 50.3 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KKK20854.1 - 1.3e-12 47.9 0.0 2.2e-12 47.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KKK20854.1 - 4.5e-12 46.4 0.0 4.7e-11 43.2 0.0 2.6 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 KKK20854.1 - 2.4e-09 37.2 0.0 3.9e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KKK20854.1 - 1.8e-07 30.7 0.0 7.1e-07 28.8 0.0 1.8 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_24 PF13578.6 KKK20854.1 - 0.0013 19.7 0.0 0.036 15.1 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain DUF3419 PF11899.8 KKK20854.1 - 0.0033 16.7 0.0 0.0059 15.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_8 PF05148.15 KKK20854.1 - 0.0059 16.5 0.0 0.7 9.7 0.0 2.4 2 1 0 2 2 2 1 Hypothetical methyltransferase MTS PF05175.14 KKK20854.1 - 0.0063 16.1 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain NNMT_PNMT_TEMT PF01234.17 KKK20854.1 - 0.0097 15.1 0.0 0.24 10.6 0.0 2.4 1 1 1 3 3 3 1 NNMT/PNMT/TEMT family Endonuclease_NS PF01223.23 KKK20855.1 - 3.2e-64 216.9 0.0 3.8e-64 216.6 0.0 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease Mpv17_PMP22 PF04117.12 KKK20898.1 - 2.3e-12 46.9 1.6 4.7e-11 42.7 0.8 2.3 2 0 0 2 2 2 2 Mpv17 / PMP22 family Cullin_binding PF03556.15 KKK20899.1 - 4.5e-31 107.8 0.4 5.8e-31 107.4 0.4 1.1 1 0 0 1 1 1 1 Cullin binding NMD3 PF04981.13 KKK20900.1 - 5.2 6.4 6.0 2.8 7.3 0.8 2.1 2 0 0 2 2 2 0 NMD3 family PEX11 PF05648.14 KKK20901.1 - 1.4e-08 34.5 0.2 9e-07 28.6 0.2 2.1 1 1 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) DUF1039 PF06287.11 KKK20902.1 - 0.034 14.5 0.0 0.067 13.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1039) AAA PF00004.29 KKK20903.1 - 2.9e-97 322.2 0.0 3.6e-47 160.1 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KKK20903.1 - 2e-23 81.9 2.2 1.2e-12 47.4 0.3 2.8 2 0 0 2 2 2 2 AAA+ lid domain CDC48_N PF02359.18 KKK20903.1 - 7.8e-18 64.4 1.0 2.1e-17 63.1 0.4 2.1 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_2 PF07724.14 KKK20903.1 - 2.8e-14 53.6 0.0 1e-07 32.2 0.0 2.9 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 KKK20903.1 - 3.1e-14 53.0 0.0 6.6e-06 26.0 0.0 3.2 3 1 0 3 3 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 KKK20903.1 - 2e-12 47.4 0.0 2.2e-05 24.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KKK20903.1 - 2.8e-12 47.3 0.0 0.00021 21.7 0.0 4.5 3 2 1 4 4 3 2 AAA ATPase domain AAA_5 PF07728.14 KKK20903.1 - 2.6e-11 43.7 0.6 2e-05 24.6 0.1 3.7 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) TIP49 PF06068.13 KKK20903.1 - 3e-09 36.5 0.0 0.0013 18.0 0.0 2.8 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_22 PF13401.6 KKK20903.1 - 3.4e-09 37.1 0.4 0.026 14.8 0.0 4.2 2 2 0 2 2 2 2 AAA domain CDC48_2 PF02933.17 KKK20903.1 - 3.8e-09 36.2 0.0 1e-08 34.8 0.0 1.8 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 Mg_chelatase PF01078.21 KKK20903.1 - 1.6e-07 30.9 0.8 0.01 15.2 0.1 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 KKK20903.1 - 5.7e-07 29.4 0.0 0.019 14.7 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein RNA_helicase PF00910.22 KKK20903.1 - 6.4e-07 29.7 0.0 0.029 14.7 0.0 2.8 2 0 0 2 2 2 2 RNA helicase Vps4_C PF09336.10 KKK20903.1 - 7e-07 29.2 0.1 1.1e-05 25.4 0.1 2.5 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_18 PF13238.6 KKK20903.1 - 7.2e-07 29.8 0.0 0.029 14.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.6 KKK20903.1 - 1.1e-06 28.8 0.0 0.017 15.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain ATPase PF06745.13 KKK20903.1 - 2.3e-06 27.1 1.2 0.51 9.6 0.0 3.8 4 0 0 4 4 4 2 KaiC AAA_7 PF12775.7 KKK20903.1 - 6.9e-06 25.7 0.1 0.056 13.0 0.0 3.2 2 2 0 2 2 2 2 P-loop containing dynein motor region AAA_24 PF13479.6 KKK20903.1 - 7.6e-06 25.8 0.0 0.13 11.9 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_25 PF13481.6 KKK20903.1 - 1.1e-05 25.1 4.7 0.33 10.5 0.1 4.1 3 2 2 5 5 4 2 AAA domain Parvo_NS1 PF01057.17 KKK20903.1 - 1.5e-05 24.2 0.1 0.054 12.6 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 DUF815 PF05673.13 KKK20903.1 - 2.2e-05 23.7 0.0 0.017 14.3 0.0 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_28 PF13521.6 KKK20903.1 - 2.4e-05 24.6 0.1 0.18 12.0 0.0 2.8 3 0 0 3 3 2 2 AAA domain Sigma54_activat PF00158.26 KKK20903.1 - 3.3e-05 23.7 0.1 0.43 10.3 0.0 3.3 2 2 0 2 2 2 2 Sigma-54 interaction domain Bac_DnaA PF00308.18 KKK20903.1 - 4.9e-05 23.3 0.0 0.29 10.9 0.0 3.1 3 0 0 3 3 3 2 Bacterial dnaA protein ABC_tran PF00005.27 KKK20903.1 - 0.00015 22.3 0.0 0.54 10.8 0.0 3.4 2 1 0 2 2 2 1 ABC transporter ResIII PF04851.15 KKK20903.1 - 0.00016 21.7 0.0 0.078 13.0 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit TsaE PF02367.17 KKK20903.1 - 0.00016 21.6 0.0 0.34 10.9 0.0 2.5 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_17 PF13207.6 KKK20903.1 - 0.00022 21.6 0.0 0.6 10.5 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 KKK20903.1 - 0.00023 21.0 0.3 0.91 9.3 0.2 2.9 2 1 0 2 2 2 2 AAA domain PhoH PF02562.16 KKK20903.1 - 0.00028 20.4 0.4 0.7 9.3 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein NACHT PF05729.12 KKK20903.1 - 0.00031 20.7 0.1 0.18 11.7 0.0 2.9 3 0 0 3 3 3 1 NACHT domain AAA_3 PF07726.11 KKK20903.1 - 0.00038 20.3 0.0 1.1 9.1 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 KKK20903.1 - 0.00062 19.7 0.0 2.3 8.1 0.0 3.7 3 1 0 3 3 3 1 ATPase domain predominantly from Archaea AAA_30 PF13604.6 KKK20903.1 - 0.0009 19.0 0.3 0.85 9.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.9 KKK20903.1 - 0.0018 17.6 0.0 1.4 8.1 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.6 KKK20903.1 - 0.0048 17.2 0.9 5.4 7.3 0.0 3.5 3 1 0 4 4 2 0 AAA domain Viral_helicase1 PF01443.18 KKK20903.1 - 0.0051 16.6 0.0 0.35 10.6 0.0 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase NB-ARC PF00931.22 KKK20903.1 - 0.0094 15.2 0.0 1.6 7.8 0.0 2.5 2 0 0 2 2 2 1 NB-ARC domain Zeta_toxin PF06414.12 KKK20903.1 - 0.0097 15.2 0.0 6 6.1 0.0 2.8 2 0 0 2 2 2 0 Zeta toxin KAP_NTPase PF07693.14 KKK20903.1 - 0.011 15.0 0.2 0.93 8.7 0.0 3.0 2 2 0 3 3 3 0 KAP family P-loop domain NTPase_1 PF03266.15 KKK20903.1 - 0.011 15.7 0.5 2.5 8.0 0.0 3.7 3 0 0 3 3 3 0 NTPase IPT PF01745.16 KKK20903.1 - 0.016 14.6 0.0 2.4 7.5 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase Sigma54_activ_2 PF14532.6 KKK20903.1 - 0.028 14.6 0.0 3.8 7.6 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain Zot PF05707.12 KKK20903.1 - 0.036 13.7 0.2 2 8.0 0.0 3.2 2 2 1 3 3 3 0 Zonular occludens toxin (Zot) Cytidylate_kin PF02224.18 KKK20903.1 - 0.06 13.1 0.4 10 5.8 0.0 2.9 3 0 0 3 3 2 0 Cytidylate kinase AFG1_ATPase PF03969.16 KKK20903.1 - 0.069 12.0 0.0 9.4 5.0 0.0 2.3 2 0 0 2 2 2 0 AFG1-like ATPase AAA_6 PF12774.7 KKK20903.1 - 0.075 12.0 0.3 9.1 5.1 0.0 2.5 3 0 0 3 3 2 0 Hydrolytic ATP binding site of dynein motor region UFD1 PF03152.14 KKK20903.1 - 0.091 12.2 0.0 0.66 9.4 0.0 2.0 1 1 1 2 2 2 0 Ubiquitin fusion degradation protein UFD1 EnY2 PF10163.9 KKK20904.1 - 0.00063 20.1 0.0 0.00092 19.5 0.0 1.2 1 0 0 1 1 1 1 Transcription factor e(y)2 Pkinase PF00069.25 KKK20907.1 - 2.4e-17 63.2 0.0 8.2e-17 61.4 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK20907.1 - 7.6e-13 48.3 0.0 4.1e-12 45.9 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KKK20907.1 - 0.036 13.4 0.0 0.056 12.8 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family zf-C3HC4_3 PF13920.6 KKK20910.1 - 1e-09 38.1 11.3 1.6e-09 37.4 11.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KKK20910.1 - 0.0068 16.2 12.3 0.012 15.4 12.3 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 CFEM PF05730.11 KKK20911.1 - 5.5e-15 55.2 11.3 8.9e-15 54.5 11.3 1.3 1 0 0 1 1 1 1 CFEM domain DUF908 PF06012.12 KKK20911.1 - 0.51 9.7 9.1 0.6 9.5 9.1 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Apt1 PF10351.9 KKK20911.1 - 0.55 9.0 5.3 0.6 8.9 5.3 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain SOG2 PF10428.9 KKK20911.1 - 0.63 9.2 16.1 0.71 9.0 16.1 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein IMUP PF15761.5 KKK20911.1 - 2.2 9.0 13.9 4.6 8.0 13.9 1.6 1 0 0 1 1 1 0 Immortalisation up-regulated protein SPX PF03105.19 KKK20911.1 - 2.2 8.1 9.2 2.6 7.9 9.2 1.0 1 0 0 1 1 1 0 SPX domain APH PF01636.23 KKK20912.1 - 2.7e-13 50.4 0.0 7.1e-13 49.0 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KKK20912.1 - 0.00083 18.8 0.0 0.25 10.7 0.0 2.7 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 KKK20912.1 - 0.0066 16.1 0.0 0.015 14.9 0.0 1.6 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF1679 PF07914.11 KKK20912.1 - 0.018 13.9 0.0 1.3 7.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) Pkinase PF00069.25 KKK20912.1 - 0.12 11.7 0.0 4.8 6.5 0.0 2.2 2 0 0 2 2 2 0 Protein kinase domain adh_short_C2 PF13561.6 KKK20913.1 - 4.7e-32 111.4 0.1 8.1e-29 100.8 0.0 2.4 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase tRNA_int_end_N2 PF12928.7 KKK20913.1 - 5.6e-31 106.5 0.0 1e-30 105.7 0.0 1.5 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term adh_short PF00106.25 KKK20913.1 - 5.9e-31 107.4 0.0 1.8e-22 79.8 0.0 2.5 2 1 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 KKK20913.1 - 5.9e-08 32.8 0.1 5.8e-07 29.6 0.1 2.4 2 1 0 2 2 2 1 KR domain tRNA_int_endo_N PF02778.14 KKK20913.1 - 0.038 13.7 0.0 0.079 12.6 0.0 1.4 1 0 0 1 1 1 0 tRNA intron endonuclease, N-terminal domain Epimerase PF01370.21 KKK20913.1 - 0.18 11.2 0.1 4.5 6.6 0.2 3.0 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family ThiF PF00899.21 KKK20914.1 - 9.1e-74 247.9 0.0 1.2e-73 247.4 0.0 1.1 1 0 0 1 1 1 1 ThiF family UAE_UbL PF14732.6 KKK20914.1 - 2.8e-14 53.4 0.0 9.5e-14 51.8 0.0 1.9 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain UBA_e1_thiolCys PF10585.9 KKK20914.1 - 3.7e-11 43.4 2.6 1e-06 28.9 0.1 2.8 1 1 1 2 2 2 2 Ubiquitin-activating enzyme active site NAD_binding_7 PF13241.6 KKK20914.1 - 0.00032 21.1 0.3 0.0014 19.0 0.0 2.2 3 0 0 3 3 3 1 Putative NAD(P)-binding Shikimate_DH PF01488.20 KKK20914.1 - 0.02 14.9 0.0 0.15 12.1 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.27 KKK20914.1 - 0.023 15.3 0.0 3.3 8.3 0.0 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Polbeta PF18765.1 KKK20914.1 - 0.026 14.6 3.8 1.9 8.6 1.2 2.9 2 1 0 2 2 2 0 Polymerase beta, Nucleotidyltransferase Seryl_tRNA_N PF02403.22 KKK20914.1 - 2.3 8.5 5.4 1.8 8.8 0.0 3.0 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain DNA_pol_delta_4 PF04081.13 KKK20915.1 - 1.1e-35 122.8 1.7 2.8e-35 121.5 1.7 1.7 1 1 0 1 1 1 1 DNA polymerase delta, subunit 4 NADPH_Ox PF08414.10 KKK20915.1 - 0.075 13.4 0.2 1.3 9.4 0.2 2.2 2 0 0 2 2 2 0 Respiratory burst NADPH oxidase Ndc1_Nup PF09531.10 KKK20915.1 - 0.93 8.1 4.6 1.1 7.9 4.6 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Arrestin_C PF02752.22 KKK20916.1 - 5.1e-12 46.4 0.0 2e-11 44.5 0.0 1.9 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain NUDIX PF00293.28 KKK20942.1 - 3.1e-26 92.0 0.9 3.7e-26 91.7 0.9 1.1 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 KKK20942.1 - 0.013 15.5 0.1 0.021 14.8 0.1 1.3 1 1 0 1 1 1 0 NUDIX domain AdoMet_MTase PF07757.13 KKK20949.1 - 1.3e-34 118.9 0.2 2.8e-33 114.6 0.2 2.3 1 1 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase SPX PF03105.19 KKK20949.1 - 0.62 9.9 4.3 1.3 8.9 4.3 1.6 1 0 0 1 1 1 0 SPX domain CorA PF01544.18 KKK20950.1 - 5.3e-08 32.5 0.1 7.5e-08 32.0 0.1 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein RadC PF04002.15 KKK20950.1 - 0.2 11.6 0.3 3 7.8 0.1 2.3 2 0 0 2 2 2 0 RadC-like JAB domain ApoL PF05461.11 KKK20950.1 - 8.3 5.6 8.6 0.058 12.7 0.5 1.5 2 0 0 2 2 2 0 Apolipoprotein L WH2 PF02205.20 KKK20951.1 - 0.00098 18.9 4.5 0.027 14.3 4.5 2.4 1 1 0 1 1 1 1 WH2 motif ApbA PF02558.16 KKK20952.1 - 5.6e-26 91.0 0.0 8.1e-26 90.5 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 KKK20952.1 - 3.4e-22 79.0 0.0 5.1e-22 78.4 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal DASH_Hsk3 PF08227.11 KKK20953.1 - 1.9e-21 76.1 0.8 3.4e-21 75.3 0.8 1.4 1 0 0 1 1 1 1 DASH complex subunit Hsk3 like Phostensin PF13914.6 KKK20953.1 - 0.01 16.5 0.0 0.017 15.8 0.0 1.2 1 0 0 1 1 1 0 Phostensin PP1-binding and SH3-binding region BBS2_C PF14782.6 KKK20953.1 - 0.014 14.2 0.0 0.017 13.9 0.0 1.2 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, C-terminal His_Phos_1 PF00300.22 KKK20954.1 - 1.8e-34 119.2 2.1 3.7e-32 111.6 2.1 2.8 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DUF1489 PF07370.11 KKK20956.1 - 0.013 15.2 0.1 0.057 13.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1489) F-box PF00646.33 KKK20956.1 - 0.042 13.7 0.8 1.7 8.6 0.0 2.7 2 0 0 2 2 2 0 F-box domain RACo_linker PF17650.1 KKK20957.1 - 0.18 11.7 0.1 0.29 11.0 0.1 1.3 1 0 0 1 1 1 0 RACo linker region Peptidase_C14 PF00656.22 KKK20960.1 - 3.3e-47 161.5 0.0 4e-47 161.2 0.0 1.1 1 0 0 1 1 1 1 Caspase domain VWA_3 PF13768.6 KKK20960.1 - 0.17 11.8 0.0 1.4 8.9 0.0 2.0 2 0 0 2 2 2 0 von Willebrand factor type A domain Methyltransf_16 PF10294.9 KKK20961.1 - 1.4e-13 50.9 0.0 2e-13 50.4 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase KTI12 PF08433.10 KKK20962.1 - 3.8e-64 216.8 0.0 1.3e-63 215.0 0.0 1.8 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.6 KKK20962.1 - 0.00082 19.6 0.1 0.003 17.7 0.0 2.0 3 0 0 3 3 3 1 AAA domain PHD PF00628.29 KKK20969.1 - 1.7e-08 34.2 7.4 2.8e-08 33.5 7.4 1.3 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 KKK20969.1 - 0.38 10.4 5.9 0.66 9.6 5.9 1.4 1 0 0 1 1 1 0 PHD-finger zf-RING_2 PF13639.6 KKK20969.1 - 4.1 7.8 8.0 7.4 7.0 8.0 1.4 1 0 0 1 1 1 0 Ring finger domain zf-RING_11 PF17123.5 KKK20969.1 - 5 7.0 5.8 9.8 6.0 5.8 1.5 1 0 0 1 1 1 0 RING-like zinc finger DUF2293 PF10056.9 KKK20970.1 - 6.5e-29 100.0 1.1 3e-28 97.9 0.0 2.6 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2293) MFS_1 PF07690.16 KKK20971.1 - 8.6e-29 100.5 23.8 1.6e-28 99.6 20.5 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily rhaM PF05336.13 KKK20971.1 - 2.6e-15 56.4 0.0 4.5e-15 55.6 0.0 1.3 1 0 0 1 1 1 1 L-rhamnose mutarotase Pyr_redox_2 PF07992.14 KKK20972.1 - 1.9e-44 152.1 0.1 3.3e-44 151.3 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NIR_SIR PF01077.22 KKK20972.1 - 2.9e-20 72.4 0.0 7.1e-20 71.1 0.0 1.7 1 0 0 1 1 1 1 Nitrite and sulphite reductase 4Fe-4S domain Pyr_redox PF00070.27 KKK20972.1 - 1.7e-18 67.0 1.9 2.6e-17 63.1 0.3 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Fer2_BFD PF04324.15 KKK20972.1 - 3.5e-16 59.3 7.7 5.7e-13 49.0 5.3 2.9 2 0 0 2 2 2 2 BFD-like [2Fe-2S] binding domain Rieske PF00355.26 KKK20972.1 - 2.3e-13 49.9 0.0 1.5e-12 47.2 0.0 2.3 2 0 0 2 2 2 1 Rieske [2Fe-2S] domain NIR_SIR_ferr PF03460.17 KKK20972.1 - 1e-11 44.5 0.0 2.1e-11 43.5 0.0 1.6 1 0 0 1 1 1 1 Nitrite/Sulfite reductase ferredoxin-like half domain Rieske_2 PF13806.6 KKK20972.1 - 3.6e-11 42.9 0.0 8.9e-11 41.7 0.0 1.7 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Rubredoxin_C PF18267.1 KKK20972.1 - 3.4e-06 26.9 0.3 0.04 13.8 0.1 3.5 3 0 0 3 3 3 2 Rubredoxin NAD+ reductase C-terminal domain NAD_binding_9 PF13454.6 KKK20972.1 - 0.0038 17.2 0.6 6.2 6.8 0.0 3.7 3 1 1 4 4 4 1 FAD-NAD(P)-binding HI0933_like PF03486.14 KKK20972.1 - 0.013 14.2 0.0 1.1 7.8 0.0 2.5 3 0 0 3 3 3 0 HI0933-like protein Phosphorylase PF00343.20 KKK20973.1 - 0 1056.1 0.0 0 1055.9 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase zf-C2HC_2 PF13913.6 KKK20973.1 - 0.34 10.9 1.8 22 5.1 0.1 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type ABC_membrane_2 PF06472.15 KKK20974.1 - 6e-106 353.8 0.6 1.1e-105 352.9 0.6 1.4 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 KKK20974.1 - 2.1e-17 63.9 0.0 4e-17 63.0 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KKK20974.1 - 8e-05 22.6 0.0 0.00026 20.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KKK20974.1 - 0.0055 17.2 0.0 0.011 16.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 KKK20974.1 - 0.015 15.1 0.0 0.036 13.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Glyco_transf_22 PF03901.17 KKK20974.1 - 0.043 13.1 0.1 0.069 12.4 0.1 1.3 1 0 0 1 1 1 0 Alg9-like mannosyltransferase family SMC_N PF02463.19 KKK20974.1 - 0.05 13.0 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain RuvB_N PF05496.12 KKK20974.1 - 0.052 13.3 0.1 1.5 8.6 0.0 2.7 3 0 0 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain Rad17 PF03215.15 KKK20974.1 - 0.12 12.3 0.0 0.29 11.0 0.0 1.6 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_27 PF13514.6 KKK20974.1 - 0.12 11.9 0.0 0.3 10.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KKK20974.1 - 0.17 12.2 0.5 0.95 9.8 0.1 2.3 2 0 0 2 2 2 0 AAA ATPase domain Pkinase PF00069.25 KKK20975.1 - 3.3e-66 223.4 0.0 4.2e-66 223.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK20975.1 - 1.6e-30 106.2 0.0 2.2e-30 105.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KKK20975.1 - 1.1e-05 24.5 0.1 1.5e-05 24.1 0.1 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KKK20975.1 - 0.00017 21.0 0.1 0.00059 19.3 0.1 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KKK20975.1 - 0.00031 20.1 0.0 0.063 12.6 0.0 2.3 1 1 1 2 2 2 2 Kinase-like APH PF01636.23 KKK20975.1 - 0.001 19.1 0.0 0.0023 17.9 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.6 KKK20975.1 - 0.014 15.0 0.0 0.027 14.1 0.0 1.5 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 KKK20975.1 - 0.046 13.3 0.0 0.072 12.7 0.0 1.3 1 0 0 1 1 1 0 RIO1 family G-alpha PF00503.20 KKK20976.1 - 2.7e-113 378.7 0.1 3.1e-113 378.5 0.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KKK20976.1 - 6.4e-15 55.0 0.2 5.4e-10 39.0 0.0 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KKK20976.1 - 0.00019 20.9 0.1 0.33 10.3 0.0 2.2 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 KKK20976.1 - 0.0089 16.2 0.2 1 9.6 0.1 2.4 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 KKK20976.1 - 0.11 12.2 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain FTA4 PF13093.6 KKK20977.1 - 1.1e-35 123.4 8.2 1.4e-35 123.0 8.2 1.1 1 0 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 DUF3584 PF12128.8 KKK20977.1 - 0.002 15.7 5.0 0.0023 15.5 5.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) ALIX_LYPXL_bnd PF13949.6 KKK20977.1 - 0.0039 16.5 3.7 0.0052 16.1 3.7 1.2 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV FapA PF03961.13 KKK20977.1 - 0.23 10.0 0.4 0.26 9.9 0.4 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Wtap PF17098.5 KKK20978.1 - 0.0018 18.2 0.4 0.017 15.0 0.4 2.3 2 0 0 2 2 2 1 WTAP/Mum2p family SlyX PF04102.12 KKK20978.1 - 0.0089 16.6 0.6 0.08 13.6 0.1 2.7 3 0 0 3 3 3 1 SlyX GlutR_dimer PF00745.20 KKK20978.1 - 0.032 14.7 1.0 0.1 13.0 0.4 2.3 2 1 0 2 2 2 0 Glutamyl-tRNAGlu reductase, dimerisation domain CENP-H PF05837.12 KKK20978.1 - 0.055 13.9 1.5 0.13 12.6 1.5 1.6 1 0 0 1 1 1 0 Centromere protein H (CENP-H) SIKE PF05769.11 KKK20978.1 - 0.28 11.1 7.3 0.36 10.7 7.3 1.1 1 0 0 1 1 1 0 SIKE family LRR_4 PF12799.7 KKK20979.1 - 0.027 14.9 5.6 6.2 7.4 0.1 5.3 2 1 4 6 6 6 0 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KKK20979.1 - 0.093 12.8 3.6 1.7e+02 2.7 0.0 6.3 8 0 0 8 8 8 0 Leucine Rich repeat CDC45 PF02724.14 KKK20979.1 - 0.52 8.6 4.0 0.81 7.9 4.0 1.3 1 0 0 1 1 1 0 CDC45-like protein Ribosomal_L5e PF17144.4 KKK20980.1 - 2e-81 271.8 0.3 3.9e-81 270.8 0.3 1.5 1 0 0 1 1 1 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 KKK20980.1 - 5e-34 117.1 8.6 5e-34 117.1 8.6 2.1 3 0 0 3 3 3 1 Ribosomal L18 C-terminal region HAD_2 PF13419.6 KKK20980.1 - 0.0034 17.5 0.0 0.011 15.9 0.0 1.9 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Mit_KHE1 PF10173.9 KKK20981.1 - 1.2e-63 214.6 0.8 1.6e-63 214.2 0.8 1.1 1 0 0 1 1 1 1 Mitochondrial K+-H+ exchange-related DUF4478 PF14793.6 KKK20981.1 - 0.18 11.7 0.0 0.27 11.1 0.0 1.3 1 0 0 1 1 1 0 Pyrimidine/purine nucleotide 5'-monophosphate nucleosidases End3 PF12761.7 KKK20982.1 - 9.3e-69 231.6 1.3 1.3e-68 231.1 1.3 1.2 1 0 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 EF-hand_4 PF12763.7 KKK20982.1 - 2.6e-51 171.9 0.2 5.3e-48 161.3 0.1 2.3 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 KKK20982.1 - 5.2e-09 35.0 0.3 7.4e-08 31.4 0.3 2.6 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 KKK20982.1 - 2.7e-07 30.9 1.8 4.1e-06 27.2 0.1 3.1 3 1 0 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.6 KKK20982.1 - 6.1e-05 22.6 0.4 0.00036 20.2 0.2 2.4 2 0 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.6 KKK20982.1 - 0.00036 20.3 0.1 0.0027 17.5 0.1 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 KKK20982.1 - 0.0024 17.3 0.1 0.0076 15.7 0.1 1.9 1 0 0 1 1 1 1 EF hand Phlebovirus_NSM PF07246.11 KKK20982.1 - 0.65 9.3 3.3 1 8.7 3.3 1.3 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M Cupin_2 PF07883.11 KKK20983.1 - 3.5e-08 33.0 0.7 5.5e-08 32.4 0.7 1.2 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 KKK20983.1 - 1.1e-06 28.3 0.1 1.9e-06 27.5 0.1 1.3 1 0 0 1 1 1 1 Cupin ARD PF03079.14 KKK20983.1 - 2.5e-05 24.5 0.0 3.5e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 ARD/ARD' family Cupin_6 PF12852.7 KKK20983.1 - 0.0022 17.7 0.0 0.0026 17.5 0.0 1.1 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.19 KKK20983.1 - 0.054 13.4 0.1 0.076 12.9 0.1 1.3 1 0 0 1 1 1 0 AraC-like ligand binding domain DUF588 PF04535.12 KKK20984.1 - 0.032 14.0 1.1 0.061 13.1 1.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF588) Aminotran_3 PF00202.21 KKK20985.1 - 3.8e-90 302.5 0.0 4.6e-90 302.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III EGF_alliinase PF04863.13 KKK20985.1 - 0.039 14.4 0.1 0.093 13.2 0.1 1.6 1 0 0 1 1 1 0 Alliinase EGF-like domain DSPc PF00782.20 KKK20986.1 - 1.5e-07 31.3 0.0 2.1e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 KKK20986.1 - 0.016 15.5 0.0 0.024 14.9 0.0 1.3 1 0 0 1 1 1 0 Rit1 DUSP-like domain SNF2_N PF00176.23 KKK20987.1 - 2.8e-64 217.0 0.0 6.7e-64 215.8 0.0 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KKK20987.1 - 1.4e-21 77.0 0.7 1.1e-20 74.1 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KKK20987.1 - 9.9e-08 32.2 0.1 4.8e-07 29.9 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 KKK20987.1 - 0.00099 18.4 3.5 0.005 16.1 0.1 3.2 3 1 0 3 3 3 1 Class II histone deacetylase complex subunits 2 and 3 TniB PF05621.11 KKK20987.1 - 0.035 13.5 0.1 3.8 6.9 0.1 2.5 2 0 0 2 2 2 0 Bacterial TniB protein Shugoshin_C PF07557.11 KKK20987.1 - 1 9.2 4.0 9.8 6.1 4.0 2.6 1 1 0 1 1 1 0 Shugoshin C terminus CCDC53 PF10152.9 KKK20987.1 - 4.4 7.7 12.0 8.4 6.8 9.7 2.5 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex DDHD PF02862.17 KKK20987.1 - 5 7.2 9.1 2.6 8.1 1.7 2.8 2 1 0 2 2 2 0 DDHD domain Avl9 PF09794.9 KKK20989.1 - 1.8e-137 458.1 0.1 3.5e-121 404.5 0.0 2.2 2 0 0 2 2 2 2 Transport protein Avl9 SPA PF08616.10 KKK20989.1 - 2.2e-09 37.3 0.1 3.3e-05 23.8 0.0 2.4 2 0 0 2 2 2 2 Stabilization of polarity axis DUF2347 PF09804.9 KKK20989.1 - 0.64 9.5 11.5 0.063 12.9 0.3 3.1 3 1 0 3 3 3 0 Uncharacterized conserved protein (DUF2347) Cullin PF00888.22 KKK20990.1 - 2.2e-192 641.0 11.0 3e-192 640.5 11.0 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 KKK20990.1 - 1.7e-26 92.0 2.2 1.7e-26 92.0 2.2 2.7 4 0 0 4 4 4 1 Cullin protein neddylation domain DUF1906 PF08924.11 KKK20990.1 - 0.079 13.1 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1906) DUF4210 PF13915.6 KKK20991.1 - 7e-31 106.6 0.1 2e-30 105.1 0.1 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4210) Chromosome_seg PF13889.6 KKK20991.1 - 7.1e-24 83.7 0.4 1.5e-23 82.7 0.4 1.6 1 0 0 1 1 1 1 Chromosome segregation during meiosis rRNA_processing PF08524.11 KKK20992.1 - 5.9 6.9 23.2 0.72 9.9 17.0 2.2 2 1 0 2 2 2 0 rRNA processing Sec5 PF15469.6 KKK20993.1 - 1.1e-35 123.2 0.0 2.8e-35 121.9 0.0 1.8 1 0 0 1 1 1 1 Exocyst complex component Sec5 Vps51 PF08700.11 KKK20993.1 - 1.1e-05 25.4 0.2 4.9e-05 23.3 0.2 2.2 1 0 0 1 1 1 1 Vps51/Vps67 DUF3979 PF13141.6 KKK20993.1 - 0.072 13.4 0.0 0.21 11.9 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3979) Iso_dh PF00180.20 KKK20994.1 - 2.1e-90 303.4 0.0 1.6e-64 218.3 0.0 2.0 1 1 1 2 2 2 2 Isocitrate/isopropylmalate dehydrogenase HHH_2 PF12826.7 KKK20994.1 - 0.0052 16.9 0.1 0.088 12.9 0.0 2.3 2 0 0 2 2 2 1 Helix-hairpin-helix motif Eaf7 PF07904.13 KKK20995.1 - 9.6e-29 99.9 0.0 9.6e-29 99.9 0.0 2.2 2 0 0 2 2 2 1 Chromatin modification-related protein EAF7 Nop14 PF04147.12 KKK20995.1 - 0.0071 14.6 15.4 0.0086 14.4 15.4 1.1 1 0 0 1 1 1 1 Nop14-like family RNA_pol_3_Rpc31 PF11705.8 KKK20995.1 - 0.036 14.3 19.8 0.072 13.3 19.8 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 TFIIF_alpha PF05793.12 KKK20995.1 - 0.053 12.1 15.6 0.073 11.7 15.6 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Cwf_Cwc_15 PF04889.12 KKK20995.1 - 0.081 12.6 17.6 0.13 12.0 17.6 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein NOA36 PF06524.12 KKK20995.1 - 0.089 12.1 14.3 0.16 11.3 14.3 1.4 1 0 0 1 1 1 0 NOA36 protein SDA1 PF05285.12 KKK20995.1 - 0.44 9.9 18.2 0.61 9.5 18.2 1.2 1 0 0 1 1 1 0 SDA1 PPP4R2 PF09184.11 KKK20995.1 - 0.74 9.4 13.7 1.2 8.7 13.7 1.4 1 0 0 1 1 1 0 PPP4R2 SAPS PF04499.15 KKK20995.1 - 0.89 8.3 5.0 0.99 8.1 5.0 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SpoIIIAH PF12685.7 KKK20995.1 - 3.1 7.6 8.3 4.1 7.2 8.3 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein Mpp10 PF04006.12 KKK20995.1 - 3.2 6.1 18.6 4.9 5.5 18.6 1.2 1 0 0 1 1 1 0 Mpp10 protein Nop53 PF07767.11 KKK20995.1 - 3.3 7.0 19.2 0.76 9.1 15.5 1.7 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) FYDLN_acid PF09538.10 KKK20995.1 - 3.5 8.3 18.5 5.2 7.8 17.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) DNA_pol_phi PF04931.13 KKK20995.1 - 3.6 5.6 29.5 4.9 5.1 29.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi TFB6 PF17110.5 KKK20995.1 - 5.4 6.7 7.0 10 5.8 7.0 1.5 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH GCP_C_terminal PF04130.13 KKK20996.1 - 1.9e-70 237.8 0.0 3.5e-70 236.9 0.0 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 KKK20996.1 - 9.7e-51 173.2 2.2 2.5e-50 171.9 2.2 1.7 1 1 0 1 1 1 1 Gamma tubulin complex component N-terminal DOG1 PF14144.6 KKK20996.1 - 0.099 12.9 0.1 0.25 11.6 0.1 1.7 1 0 0 1 1 1 0 Seed dormancy control NAD_binding_1 PF00175.21 KKK20997.1 - 1.3e-32 112.7 0.0 1.5e-32 112.5 0.0 1.1 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 KKK20997.1 - 6.8e-06 26.3 0.0 0.1 12.7 0.0 2.1 1 1 1 2 2 2 2 Ferric reductase NAD binding domain Mo-co_dimer PF03404.16 KKK20998.1 - 7.4e-60 200.9 0.0 1.3e-59 200.2 0.0 1.4 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Oxidored_molyb PF00174.19 KKK20998.1 - 1.5e-50 171.2 0.0 2.4e-50 170.5 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain FAD_binding_6 PF00970.24 KKK20998.1 - 3.3e-33 114.0 0.0 5.6e-33 113.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Cyt-b5 PF00173.28 KKK20998.1 - 5.4e-13 48.9 0.0 1.3e-12 47.7 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FAM219A PF15260.6 KKK21011.1 - 0.12 12.7 2.1 0.31 11.4 2.1 1.6 1 0 0 1 1 1 0 Protein family FAM219A AF-4 PF05110.13 KKK21011.1 - 0.58 8.2 9.2 0.73 7.8 9.2 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein SKG6 PF08693.10 KKK21011.1 - 1.6 8.2 3.3 4.7 6.7 3.3 1.9 1 1 0 1 1 1 0 Transmembrane alpha-helix domain AP_endonuc_2 PF01261.24 KKK21012.1 - 2.9e-15 56.3 0.1 4.7e-15 55.6 0.1 1.4 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Zn_clus PF00172.18 KKK21013.1 - 2.3e-09 37.2 12.4 3.8e-09 36.5 12.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aa_trans PF01490.18 KKK21014.1 - 2.3e-60 204.4 16.1 1e-52 179.2 8.8 2.0 1 1 1 2 2 2 2 Transmembrane amino acid transporter protein EFTUD2 PF16004.5 KKK21014.1 - 0.034 14.7 0.7 0.034 14.7 0.7 1.6 2 0 0 2 2 2 0 116 kDa U5 small nuclear ribonucleoprotein component N-terminus adh_short_C2 PF13561.6 KKK21015.1 - 5.9e-38 130.7 0.2 2.3e-37 128.8 0.2 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KKK21015.1 - 6.3e-26 91.0 0.3 2.5e-25 89.1 0.3 2.0 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KKK21015.1 - 0.00015 21.7 0.1 0.00026 20.9 0.1 1.4 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KKK21015.1 - 0.041 13.0 0.0 0.055 12.6 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein RTA1 PF04479.13 KKK21016.1 - 1.3e-38 132.7 5.5 1.8e-38 132.2 5.5 1.2 1 0 0 1 1 1 1 RTA1 like protein CoA_binding_3 PF13727.6 KKK21016.1 - 5.5 7.0 8.8 8.4 6.4 3.6 2.2 2 0 0 2 2 2 0 CoA-binding domain APH PF01636.23 KKK21018.1 - 0.047 13.6 0.4 0.17 11.8 0.2 1.8 2 1 0 2 2 2 0 Phosphotransferase enzyme family Zn_clus PF00172.18 KKK21019.1 - 8.5e-08 32.2 10.7 1.5e-07 31.4 10.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KKK21019.1 - 4.2e-06 26.0 1.2 4.2e-06 26.0 1.2 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain DSPc PF00782.20 KKK21020.1 - 0.0098 15.7 0.0 0.013 15.3 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PAXX PF15384.6 KKK21020.1 - 0.14 11.8 0.2 0.2 11.3 0.2 1.2 1 0 0 1 1 1 0 PAXX, PAralog of XRCC4 and XLF, also called C9orf142 AA_permease_2 PF13520.6 KKK21021.1 - 9.9e-49 166.3 42.9 1.3e-48 166.0 42.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KKK21021.1 - 6.4e-23 81.1 38.3 8.7e-23 80.6 38.3 1.1 1 0 0 1 1 1 1 Amino acid permease SID-1_RNA_chan PF13965.6 KKK21021.1 - 0.0014 17.1 0.2 0.0014 17.1 0.2 1.9 2 0 0 2 2 2 1 dsRNA-gated channel SID-1 HbrB PF08539.11 KKK21040.1 - 1.5e-50 171.5 0.0 3e-50 170.5 0.0 1.6 1 0 0 1 1 1 1 HbrB-like Gon7 PF08738.10 KKK21041.1 - 2.2e-13 50.2 0.6 7.6e-13 48.5 0.2 1.7 1 1 1 2 2 2 1 Gon7 family 6PF2K PF01591.18 KKK21042.1 - 1.9e-76 256.3 0.2 5.5e-76 254.8 0.0 1.8 2 0 0 2 2 2 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 KKK21042.1 - 8e-40 136.6 0.0 1.5e-39 135.7 0.0 1.5 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Vps39_1 PF10366.9 KKK21042.1 - 7.8e-34 116.2 0.0 8.3e-32 109.7 0.0 2.8 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.9 KKK21042.1 - 3.6e-31 107.8 0.5 1.7e-30 105.7 0.0 2.5 4 0 0 4 4 4 1 Vacuolar sorting protein 39 domain 2 CNH PF00780.22 KKK21042.1 - 3.4e-16 59.7 0.0 1.9e-15 57.3 0.0 2.0 1 1 0 1 1 1 1 CNH domain KTI12 PF08433.10 KKK21042.1 - 0.0001 21.9 0.0 0.00021 20.8 0.0 1.5 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.6 KKK21042.1 - 0.00011 22.4 0.0 0.00027 21.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain Clathrin PF00637.20 KKK21042.1 - 0.00083 19.3 0.6 0.00083 19.3 0.6 2.9 3 0 0 3 3 3 1 Region in Clathrin and VPS DinB_2 PF12867.7 KKK21042.1 - 0.065 13.7 0.6 1.8 9.1 0.0 3.1 2 1 1 3 3 3 0 DinB superfamily TPR_1 PF00515.28 KKK21042.1 - 0.34 10.8 1.9 34 4.5 0.9 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat AAA PF00004.29 KKK21043.1 - 1.7e-16 60.9 0.1 5.8e-16 59.1 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KKK21043.1 - 0.00068 19.6 0.0 0.0022 18.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KKK21043.1 - 0.00083 19.6 0.6 0.009 16.3 0.1 2.6 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 KKK21043.1 - 0.006 17.0 1.8 0.0089 16.4 0.1 2.2 2 1 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.6 KKK21043.1 - 0.031 14.4 1.7 0.18 11.9 0.0 2.9 2 1 0 2 2 2 0 AAA domain AAA_19 PF13245.6 KKK21043.1 - 0.067 13.5 0.0 0.21 11.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain SOG2 PF10428.9 KKK21044.1 - 0.00085 18.6 7.2 0.001 18.4 7.2 1.1 1 0 0 1 1 1 1 RAM signalling pathway protein Myb_DNA-bind_5 PF13873.6 KKK21044.1 - 0.0016 18.5 0.3 0.17 12.0 0.1 2.9 2 1 1 3 3 3 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_3 PF12776.7 KKK21044.1 - 0.0077 17.2 0.2 1.6 9.7 0.0 2.3 1 1 1 2 2 2 1 Myb/SANT-like DNA-binding domain RBR PF17208.3 KKK21044.1 - 0.011 16.5 3.3 0.011 16.5 3.3 3.3 2 1 1 3 3 3 0 RNA binding Region RAP1 PF07218.11 KKK21044.1 - 0.21 9.9 2.4 0.25 9.6 2.4 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Ribosomal_60s PF00428.19 KKK21044.1 - 0.64 10.7 18.2 0.11 13.2 9.7 2.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein FMO-like PF00743.19 KKK21046.1 - 5.4e-22 77.9 0.5 4.2e-21 75.0 0.2 2.3 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KKK21046.1 - 4.4e-19 68.9 0.2 6.1e-18 65.1 0.1 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KKK21046.1 - 1.5e-13 50.6 0.0 3.7e-11 42.8 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KKK21046.1 - 3.1e-10 39.7 1.6 8.1e-08 31.8 0.1 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KKK21046.1 - 1e-09 38.4 0.0 3.3e-09 36.9 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KKK21046.1 - 6.6e-08 32.5 0.2 8.3e-07 28.9 0.1 2.3 2 1 0 2 2 2 1 FAD dependent oxidoreductase Shikimate_DH PF01488.20 KKK21046.1 - 2.2e-06 27.8 0.1 0.11 12.6 0.0 2.8 3 0 0 3 3 3 2 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.27 KKK21046.1 - 4.2e-05 24.0 0.3 0.26 11.9 0.2 2.9 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KKK21046.1 - 0.0008 19.4 0.8 0.035 14.1 0.0 3.4 3 1 0 3 3 3 1 FAD-NAD(P)-binding Thi4 PF01946.17 KKK21046.1 - 0.00086 18.6 0.1 0.0024 17.2 0.1 1.7 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.24 KKK21046.1 - 0.00087 18.5 0.1 0.0014 17.8 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_7 PF13241.6 KKK21046.1 - 0.0014 19.0 0.0 0.22 12.0 0.1 2.7 2 1 0 2 2 2 1 Putative NAD(P)-binding HI0933_like PF03486.14 KKK21046.1 - 0.045 12.5 2.1 0.063 12.0 0.4 2.0 2 0 0 2 2 2 0 HI0933-like protein AA_permease PF00324.21 KKK21047.1 - 5.4e-104 348.4 35.5 6.8e-104 348.1 35.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KKK21047.1 - 5.6e-33 114.4 39.9 6.4e-33 114.2 39.9 1.0 1 0 0 1 1 1 1 Amino acid permease Peptidase_S28 PF05577.12 KKK21048.1 - 5.1e-45 154.1 0.0 3.6e-44 151.3 0.0 1.9 1 1 0 1 1 1 1 Serine carboxypeptidase S28 Utp8 PF10395.9 KKK21049.1 - 1.3e-11 43.8 0.4 5.4e-10 38.4 0.2 2.9 3 1 0 3 3 3 1 Utp8 family Fungal_trans PF04082.18 KKK21050.1 - 8.9e-21 74.1 0.1 1.4e-20 73.5 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 KKK21050.1 - 1.3e-08 34.8 14.0 0.0005 20.4 1.4 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KKK21050.1 - 9.2e-07 29.0 5.8 9.2e-07 29.0 5.8 3.1 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KKK21050.1 - 0.0017 19.0 15.5 0.12 13.3 1.5 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger DUF4072 PF13284.6 KKK21050.1 - 0.052 14.0 2.3 0.15 12.5 2.3 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4072) SUIM_assoc PF16619.5 KKK21050.1 - 0.083 13.0 2.5 0.22 11.6 1.1 2.5 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 zf-C2H2_6 PF13912.6 KKK21050.1 - 0.51 10.4 4.3 1.3 9.1 4.3 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KKK21050.1 - 1.3 8.9 7.1 6.4 6.6 1.0 2.6 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2H2_jaz PF12171.8 KKK21050.1 - 1.9 8.9 3.4 3.2 8.2 0.5 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding AAA PF00004.29 KKK21051.1 - 2.4e-09 37.7 0.0 1.3e-08 35.3 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 KKK21051.1 - 2.9e-06 27.3 0.1 0.0008 19.4 0.0 3.2 3 0 0 3 3 3 1 Rad17 P-loop domain AAA_16 PF13191.6 KKK21051.1 - 1.4e-05 25.5 0.0 3.1e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KKK21051.1 - 2.6e-05 24.5 0.0 8.7e-05 22.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KKK21051.1 - 0.00017 22.1 0.0 0.00059 20.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 KKK21051.1 - 0.0055 16.5 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KKK21051.1 - 0.024 14.6 0.0 0.059 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) TIP49 PF06068.13 KKK21051.1 - 0.025 13.8 0.0 0.051 12.8 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_11 PF13086.6 KKK21051.1 - 0.032 14.0 0.3 12 5.6 0.0 3.2 3 0 0 3 3 3 0 AAA domain AAA_7 PF12775.7 KKK21051.1 - 0.033 13.7 0.0 0.068 12.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF815 PF05673.13 KKK21051.1 - 0.088 12.0 0.0 0.19 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) T2SSE PF00437.20 KKK21051.1 - 0.099 11.7 0.0 0.19 10.8 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AP3D1 PF06375.11 KKK21051.1 - 8 6.7 13.7 2.3 8.4 5.9 2.9 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 Ala_racemase_N PF01168.20 KKK21068.1 - 3.6e-28 98.7 0.1 4.4e-28 98.4 0.1 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain D-ser_dehydrat PF14031.6 KKK21068.1 - 9.4e-21 74.3 0.0 1.7e-20 73.4 0.0 1.5 1 0 0 1 1 1 1 Putative serine dehydratase domain SDH_alpha PF03313.15 KKK21068.1 - 0.02 14.6 1.0 0.15 11.7 0.6 2.1 2 0 0 2 2 2 0 Serine dehydratase alpha chain Pkinase PF00069.25 KKK21069.1 - 2.3e-24 86.2 0.0 4.1e-24 85.4 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK21069.1 - 3.3e-07 29.8 0.0 5.5e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KKK21069.1 - 0.0001 21.2 0.0 0.00012 21.0 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KKK21069.1 - 0.0087 15.4 0.5 0.014 14.8 0.5 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KKK21069.1 - 0.12 12.3 0.7 0.26 11.2 0.4 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family ABC2_membrane PF01061.24 KKK21071.1 - 4.8e-78 261.4 61.9 2e-40 138.5 25.0 3.2 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 KKK21071.1 - 4.9e-36 124.3 0.0 1.3e-16 61.3 0.0 3.2 3 0 0 3 3 3 2 ABC transporter PDR_CDR PF06422.12 KKK21071.1 - 2.1e-26 91.6 12.6 9.8e-25 86.3 0.1 3.1 3 0 0 3 3 2 2 CDR ABC transporter ABC_trans_N PF14510.6 KKK21071.1 - 6e-14 52.4 0.1 2.2e-13 50.6 0.1 2.0 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_16 PF13191.6 KKK21071.1 - 5.3e-05 23.7 0.3 0.017 15.5 0.1 2.6 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 KKK21071.1 - 0.00015 21.7 0.3 0.00095 19.1 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase AAA_25 PF13481.6 KKK21071.1 - 0.00017 21.2 0.1 0.0044 16.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain ABC2_membrane_3 PF12698.7 KKK21071.1 - 0.00032 19.9 23.2 0.00032 19.9 23.2 3.1 2 2 1 3 3 3 2 ABC-2 family transporter protein Zeta_toxin PF06414.12 KKK21071.1 - 0.00049 19.4 0.0 0.0012 18.2 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin AAA_33 PF13671.6 KKK21071.1 - 0.00056 20.1 0.0 0.23 11.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KKK21071.1 - 0.00082 19.1 2.2 0.025 14.3 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_23 PF13476.6 KKK21071.1 - 0.03 14.8 0.0 0.49 10.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KKK21071.1 - 0.047 14.2 0.0 0.4 11.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.6 KKK21071.1 - 0.051 13.4 1.0 0.94 9.2 0.0 2.7 2 1 1 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system cobW PF02492.19 KKK21071.1 - 0.092 12.3 2.4 0.1 12.2 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 KKK21071.1 - 0.11 12.2 0.2 1.6 8.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 KKK21071.1 - 0.14 12.6 0.2 3.1 8.2 0.0 2.7 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KKK21071.1 - 0.18 11.7 2.7 4.6 7.1 0.3 2.6 2 0 0 2 2 2 0 NACHT domain MMR_HSR1 PF01926.23 KKK21071.1 - 0.18 11.9 0.0 18 5.4 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase SMC_N PF02463.19 KKK21071.1 - 0.2 11.1 0.2 5.5 6.4 0.0 2.7 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KKK21071.1 - 0.53 10.6 3.0 2.2 8.6 0.0 3.0 3 0 0 3 3 3 0 AAA domain DUF4646 PF15496.6 KKK21072.1 - 0.035 14.7 1.2 0.57 10.8 1.2 2.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4646) CAF-1_p150 PF11600.8 KKK21072.1 - 0.72 9.5 21.1 0.11 12.2 14.6 2.2 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Acetyltransf_1 PF00583.25 KKK21073.1 - 3.1e-10 40.3 0.0 4.6e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KKK21073.1 - 1.2e-07 31.7 0.1 1.7e-07 31.2 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KKK21073.1 - 1.5e-07 31.3 0.0 2.5e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 KKK21073.1 - 5.6e-05 23.5 0.0 8.8e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KKK21073.1 - 0.0088 16.1 0.2 0.017 15.2 0.2 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Pkinase PF00069.25 KKK21074.1 - 6.3e-12 45.4 0.0 1.3e-11 44.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK21074.1 - 1.7e-06 27.5 0.0 3.1e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT PF02985.22 KKK21074.1 - 5.8e-06 26.1 0.5 0.24 11.7 0.0 4.8 4 0 0 4 4 4 2 HEAT repeat Cnd1 PF12717.7 KKK21074.1 - 1.9e-05 24.7 0.0 7.6e-05 22.8 0.0 1.9 1 1 1 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 KKK21074.1 - 0.00066 20.1 0.4 1.8 9.2 0.0 3.1 2 1 0 2 2 2 2 HEAT-like repeat HEAT_2 PF13646.6 KKK21074.1 - 0.0074 16.7 0.1 0.2 12.0 0.1 2.9 1 1 2 3 3 3 2 HEAT repeats Kinase-like PF14531.6 KKK21074.1 - 0.1 11.9 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Kinase-like FAD_binding_4 PF01565.23 KKK21076.1 - 4.3e-24 84.8 3.1 7.2e-24 84.1 3.1 1.4 1 0 0 1 1 1 1 FAD binding domain AIP3 PF03915.13 KKK21077.1 - 3e-158 527.2 3.4 6.2e-158 526.2 3.4 1.6 1 0 0 1 1 1 1 Actin interacting protein 3 Lectin_N PF03954.14 KKK21077.1 - 0.0033 17.1 1.6 0.01 15.6 0.5 2.4 1 1 1 2 2 2 1 Hepatic lectin, N-terminal domain RasGAP_C PF03836.15 KKK21077.1 - 0.067 13.3 2.8 0.29 11.3 0.9 3.2 4 1 0 4 4 4 0 RasGAP C-terminus ATG_C PF09333.11 KKK21077.1 - 0.087 13.2 0.4 1.4 9.3 0.1 3.0 3 0 0 3 3 3 0 Autophagy-related protein C terminal domain Syntaxin_2 PF14523.6 KKK21077.1 - 0.98 9.8 4.6 5.1 7.5 0.1 3.1 2 1 0 2 2 2 0 Syntaxin-like protein LsmAD PF06741.13 KKK21078.1 - 1.5e-28 99.2 3.5 1.5e-28 99.2 3.5 2.0 2 0 0 2 2 2 1 LsmAD domain SM-ATX PF14438.6 KKK21078.1 - 7e-20 71.0 0.0 1.3e-19 70.1 0.0 1.5 1 0 0 1 1 1 1 Ataxin 2 SM domain Zn_clus PF00172.18 KKK21079.1 - 2.8e-06 27.3 8.2 5.4e-06 26.4 8.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain UPF0261 PF06792.11 KKK21080.1 - 1.5e-157 524.7 0.7 2e-157 524.3 0.7 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0261) PEP_hydrolase PF09370.10 KKK21080.1 - 1.7e-132 440.6 0.6 3.1e-132 439.7 0.6 1.5 1 0 0 1 1 1 1 Phosphoenolpyruvate hydrolase-like Ssu72 PF04722.13 KKK21081.1 - 2.4e-82 275.1 0.0 2.8e-82 274.9 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein PRIMA1 PF16101.5 KKK21081.1 - 0.59 10.2 3.6 0.99 9.5 3.6 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 CAP_N PF01213.19 KKK21081.1 - 3.4 7.1 8.3 5.5 6.4 8.3 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Isochorismatase PF00857.20 KKK21082.1 - 3.7e-22 79.4 0.1 7.2e-22 78.4 0.1 1.5 1 1 0 1 1 1 1 Isochorismatase family RNase_PH PF01138.21 KKK21083.1 - 3.9e-30 105.0 1.4 6.4e-30 104.3 0.6 1.7 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 SNF2_N PF00176.23 KKK21084.1 - 1.3e-51 175.4 0.1 2e-51 174.8 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain VIGSSK PF14773.6 KKK21084.1 - 4.1e-26 90.9 0.7 1.1e-25 89.5 0.7 1.8 1 0 0 1 1 1 1 Helicase-associated putative binding domain, C-terminal Helicase_C PF00271.31 KKK21084.1 - 1.2e-21 77.2 0.0 3e-19 69.4 0.0 3.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 KKK21084.1 - 3.1e-07 29.9 0.0 6.6e-07 28.8 0.0 1.5 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 KKK21084.1 - 1.9e-06 28.0 0.3 1.2e-05 25.4 0.0 2.5 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit GIT_SHD PF08518.11 KKK21085.1 - 3.3e-21 74.6 9.8 8.5e-12 44.5 1.4 2.9 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT GIT1_C PF12205.8 KKK21085.1 - 0.0001 22.4 1.0 0.00097 19.2 0.0 2.8 2 0 0 2 2 2 1 G protein-coupled receptor kinase-interacting protein 1 C term PspB PF06667.12 KKK21085.1 - 0.0016 18.4 0.7 0.0087 16.1 0.7 2.3 1 0 0 1 1 1 1 Phage shock protein B Phage_GP20 PF06810.11 KKK21085.1 - 0.01 15.7 16.1 2 8.2 12.4 2.8 2 1 1 3 3 3 0 Phage minor structural protein GP20 LPP PF04728.13 KKK21085.1 - 9.3 6.7 8.2 2 8.9 1.3 3.6 3 1 1 4 4 4 0 Lipoprotein leucine-zipper Pro_isomerase PF00160.21 KKK21086.1 - 5.3e-44 150.3 0.1 6.9e-44 149.9 0.1 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF3605 PF12239.8 KKK21087.1 - 7.1e-55 185.5 0.1 8.7e-55 185.3 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) Oxysterol_BP PF01237.18 KKK21088.1 - 1.1e-90 304.2 0.1 4.2e-88 295.7 0.1 2.1 1 1 0 1 1 1 1 Oxysterol-binding protein Hist_deacetyl PF00850.19 KKK21089.1 - 7.2e-79 265.4 0.1 9.3e-79 265.1 0.1 1.1 1 0 0 1 1 1 1 Histone deacetylase domain Glyco_hydro_20 PF00728.22 KKK21092.1 - 2.1e-102 343.2 0.6 2.6e-102 342.9 0.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 KKK21092.1 - 4.9e-28 98.5 0.0 1e-27 97.5 0.0 1.6 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 KKK21092.1 - 5.3e-05 24.0 0.0 0.00011 23.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Cutinase PF01083.22 KKK21093.1 - 2.2e-45 154.8 0.0 2.5e-45 154.6 0.0 1.0 1 0 0 1 1 1 1 Cutinase VirJ PF06057.11 KKK21093.1 - 6.1e-05 23.0 0.0 7.7e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Bacterial virulence protein (VirJ) PE-PPE PF08237.11 KKK21093.1 - 0.00098 18.7 0.0 0.0014 18.2 0.0 1.2 1 0 0 1 1 1 1 PE-PPE domain Glyco_transf_28 PF03033.20 KKK21093.1 - 0.092 12.8 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 28 N-terminal domain SAS4 PF15460.6 KKK21094.1 - 2.4e-32 111.0 11.2 4.1e-32 110.2 11.2 1.4 1 0 0 1 1 1 1 Something about silencing, SAS, complex subunit 4 DHDPS PF00701.22 KKK21095.1 - 8.7e-45 152.6 0.0 1.1e-44 152.3 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family MFS_1 PF07690.16 KKK21096.1 - 2.3e-25 89.3 65.1 3.7e-17 62.3 33.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 KKK21096.1 - 0.15 11.4 28.9 0.23 10.7 28.9 1.6 1 1 0 1 1 1 0 Uncharacterised MFS-type transporter YbfB AMP-binding PF00501.28 KKK21096.1 - 2.3 6.7 3.5 0.49 8.9 0.1 1.5 2 0 0 2 2 2 0 AMP-binding enzyme Aa_trans PF01490.18 KKK21097.1 - 3.8e-43 147.7 34.8 4.6e-43 147.5 34.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Pal1 PF08316.11 KKK21098.1 - 7.3e-11 43.0 0.0 1.2e-10 42.3 0.0 1.4 1 0 0 1 1 1 1 Pal1 cell morphology protein HVSL PF09749.9 KKK21099.1 - 5.9e-81 271.4 0.1 8.3e-81 271.0 0.1 1.1 1 0 0 1 1 1 1 Uncharacterised conserved protein DUF3807 PF12720.7 KKK21099.1 - 1.3e-38 133.1 0.0 2.3e-38 132.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3807) Alpha-L-AF_C PF06964.12 KKK21100.1 - 4.4e-18 66.0 0.8 7.7e-18 65.2 0.8 1.4 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminal domain Glyco_hydro_79C PF16862.5 KKK21100.1 - 2.3 9.2 5.4 0.66 10.9 1.5 2.2 2 0 0 2 2 2 0 Glycosyl hydrolase family 79 C-terminal beta domain Neocarzinostat PF00960.18 KKK21100.1 - 4 7.4 11.8 13 5.8 0.0 3.5 3 0 0 3 3 3 0 Neocarzinostatin family Sugar_tr PF00083.24 KKK21101.1 - 1.2e-94 317.8 18.3 1.6e-94 317.3 18.3 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKK21101.1 - 4.2e-26 91.7 26.4 3.8e-18 65.5 12.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily APH PF01636.23 KKK21111.1 - 9.3e-09 35.5 0.0 1.5e-08 34.9 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KKK21111.1 - 2.3e-05 24.1 0.0 3.7e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase HTH_Tnp_1_2 PF13022.6 KKK21112.1 - 0.048 13.8 0.1 0.052 13.7 0.1 1.1 1 0 0 1 1 1 0 Helix-turn-helix of insertion element transposase Arrestin_C PF02752.22 KKK21113.1 - 4e-20 72.6 0.0 2.2e-19 70.2 0.0 2.1 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 KKK21113.1 - 8.1e-08 32.4 0.0 0.0027 17.8 0.0 2.4 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 KKK21113.1 - 0.018 14.7 0.0 0.08 12.6 0.0 2.0 2 0 0 2 2 2 0 Arrestin_N terminal like RRM_1 PF00076.22 KKK21115.1 - 3.7e-19 68.3 0.0 4.8e-19 67.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KKK21115.1 - 0.002 17.7 0.0 0.003 17.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KKK21115.1 - 0.025 14.6 0.0 0.034 14.1 0.0 1.2 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif KilA-N PF04383.13 KKK21118.1 - 0.00019 21.3 0.0 0.0048 16.7 0.0 2.2 1 1 0 1 1 1 1 KilA-N domain HA2 PF04408.23 KKK21119.1 - 3.1e-16 59.6 0.1 3.1e-16 59.6 0.1 2.2 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KKK21119.1 - 3.8e-14 53.0 0.1 1.1e-13 51.5 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KKK21119.1 - 3.9e-12 46.3 0.0 7.9e-12 45.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KKK21119.1 - 1.7e-05 25.1 0.1 6.5e-05 23.2 0.1 2.0 1 0 0 1 1 1 1 AAA domain OB_NTP_bind PF07717.16 KKK21119.1 - 4.4e-05 23.8 0.0 0.00011 22.5 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Gcn1_N PF12074.8 KKK21120.1 - 1.4e-108 363.4 12.0 5.2e-77 259.6 0.3 4.7 4 1 1 5 5 5 2 Generalcontrol nonderepressible 1 (Gcn1) N-terminal Ribosomal_L19e PF01280.20 KKK21120.1 - 7.7e-59 197.9 8.5 1.9e-58 196.6 8.5 1.7 1 0 0 1 1 1 1 Ribosomal protein L19e HEAT PF02985.22 KKK21120.1 - 1.2e-27 93.6 26.6 0.18 12.2 0.1 20.4 21 0 0 21 21 20 6 HEAT repeat HEAT_2 PF13646.6 KKK21120.1 - 3e-27 94.9 26.0 3.7e-07 30.4 1.2 13.2 9 3 4 13 13 13 9 HEAT repeats HEAT_EZ PF13513.6 KKK21120.1 - 9.3e-24 83.5 40.4 0.00075 19.9 0.1 19.1 16 5 6 22 22 20 5 HEAT-like repeat Cnd1 PF12717.7 KKK21120.1 - 1.7e-12 47.7 11.4 0.064 13.3 0.1 8.8 6 2 2 9 9 9 4 non-SMC mitotic condensation complex subunit 1 ParcG PF10274.9 KKK21120.1 - 1.4e-09 38.4 4.9 0.15 12.2 0.1 6.7 5 1 1 6 6 6 2 Parkin co-regulated protein CLASP_N PF12348.8 KKK21120.1 - 4.2e-09 36.3 0.0 1.2 8.7 0.0 7.0 4 2 2 7 7 7 2 CLASP N terminal Vac14_Fab1_bd PF12755.7 KKK21120.1 - 7.9e-09 36.0 0.0 7.3 7.3 0.0 8.4 7 2 3 10 10 9 1 Vacuolar 14 Fab1-binding region TIP120 PF08623.10 KKK21120.1 - 4.4e-06 26.6 0.2 0.0029 17.4 0.0 5.2 5 1 1 6 6 6 1 TATA-binding protein interacting (TIP20) Cnd3 PF12719.7 KKK21120.1 - 0.00027 20.2 6.1 0.18 11.0 0.0 4.4 3 0 0 3 3 3 2 Nuclear condensing complex subunits, C-term domain Ipi1_N PF12333.8 KKK21120.1 - 0.002 18.7 0.7 4.3 8.0 0.0 4.6 5 0 0 5 5 3 1 Rix1 complex component involved in 60S ribosome maturation DUF937 PF06078.11 KKK21120.1 - 0.0044 17.6 3.4 13 6.4 0.0 5.9 4 1 1 5 5 5 0 Bacterial protein of unknown function (DUF937) RTP1_C1 PF10363.9 KKK21120.1 - 0.058 13.6 13.6 3.1 8.0 0.1 7.1 8 0 0 8 8 7 0 Required for nuclear transport of RNA pol II C-terminus 1 DUF4487 PF14868.6 KKK21120.1 - 0.17 10.6 4.9 0.25 10.1 1.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4487) Dopey_N PF04118.14 KKK21120.1 - 1.3 8.1 5.3 50 2.8 0.0 5.1 5 2 2 7 7 7 0 Dopey, N-terminal V-ATPase_H_N PF03224.14 KKK21120.1 - 3.8 6.7 8.3 40 3.3 0.0 4.4 4 0 0 4 4 4 0 V-ATPase subunit H TIP39 PF14980.6 KKK21122.1 - 0.36 10.7 0.1 0.36 10.7 0.1 2.7 3 0 0 3 3 3 0 TIP39 peptide Aminotran_1_2 PF00155.21 KKK21139.1 - 2.3e-62 211.3 0.0 3.2e-62 210.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KKK21139.1 - 0.0069 15.4 0.0 0.011 14.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KKK21139.1 - 0.055 12.7 0.0 0.13 11.5 0.0 1.5 2 0 0 2 2 2 0 Beta-eliminating lyase Cyclin PF08613.11 KKK21140.1 - 3.7e-14 53.4 0.0 5.9e-14 52.8 0.0 1.3 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 KKK21140.1 - 0.00052 19.7 0.0 0.00085 19.1 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Ribosomal_L27A PF00828.19 KKK21141.1 - 8.3e-31 107.3 1.5 1.4e-30 106.5 1.5 1.4 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A GntR PF00392.21 KKK21141.1 - 0.15 11.7 0.1 0.68 9.6 0.0 2.0 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family Pkinase PF00069.25 KKK21142.1 - 7e-47 160.0 0.0 9.3e-47 159.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK21142.1 - 3.1e-28 98.8 0.0 4.7e-21 75.2 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 KKK21142.1 - 0.012 15.5 0.1 0.16 11.8 0.0 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KKK21142.1 - 0.033 13.0 0.0 0.06 12.1 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase Acetyltransf_10 PF13673.7 KKK21143.1 - 0.019 14.9 0.0 0.034 14.1 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain SH3_1 PF00018.28 KKK21144.1 - 5.6e-07 29.1 1.0 4.2e-06 26.3 0.0 2.4 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 KKK21144.1 - 0.0008 19.2 0.0 0.0019 18.0 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain Ish1 PF10281.9 KKK21144.1 - 0.05 13.9 0.7 0.18 12.1 0.7 2.0 1 0 0 1 1 1 0 Putative stress-responsive nuclear envelope protein SH3_16 PF18348.1 KKK21144.1 - 0.065 13.0 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 Bacterial dipeptidyl-peptidase Sh3 domain PQ-loop PF04193.14 KKK21145.1 - 1.5e-35 120.7 12.1 1.1e-17 63.6 1.2 2.5 2 0 0 2 2 2 2 PQ loop repeat MtN3_slv PF03083.16 KKK21145.1 - 3.1 7.9 5.7 4.9 7.3 0.1 2.9 3 0 0 3 3 3 0 Sugar efflux transporter for intercellular exchange Proteasome PF00227.26 KKK21170.1 - 2.4e-27 95.7 0.0 2.9e-27 95.4 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit HSP20 PF00011.21 KKK21171.1 - 1.1e-16 60.8 1.2 7.4e-13 48.5 0.2 2.3 2 0 0 2 2 2 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KKK21171.1 - 1.5e-06 27.6 0.0 0.0024 17.4 0.0 2.2 2 0 0 2 2 2 2 HSP20-like domain found in ArsA SURF2 PF05477.11 KKK21171.1 - 0.012 15.3 3.5 0.015 15.0 3.5 1.1 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) Autophagy_act_C PF03987.15 KKK21172.1 - 1.6e-13 51.0 0.2 3e-13 50.1 0.2 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain RRM_1 PF00076.22 KKK21173.1 - 4.2e-09 36.1 0.0 9.4e-09 35.0 0.0 1.6 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KKK21173.1 - 4.9e-05 22.9 0.0 6.6e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KKK21173.1 - 0.098 12.5 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Occluded RNA-recognition motif WD40 PF00400.32 KKK21174.1 - 4.3e-16 59.0 12.2 0.00028 21.6 0.0 6.7 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKK21174.1 - 1.5e-06 28.4 0.1 0.039 14.2 0.0 4.6 5 1 0 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain RhoGAP PF00620.27 KKK21175.1 - 6.8e-42 142.9 0.1 1.5e-41 141.8 0.1 1.5 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.29 KKK21175.1 - 1.5e-15 57.6 0.0 4.1e-15 56.2 0.0 1.8 2 0 0 2 2 2 1 PH domain PH_8 PF15409.6 KKK21175.1 - 0.035 14.4 0.0 0.25 11.7 0.0 2.3 2 0 0 2 2 2 0 Pleckstrin homology domain DUF3450 PF11932.8 KKK21175.1 - 0.16 11.2 1.3 0.3 10.3 1.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) KH_8 PF17903.1 KKK21176.1 - 1.5e-05 25.0 0.0 2.9e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 KKK21176.1 - 0.0014 18.4 1.8 0.0037 17.1 1.8 1.7 1 0 0 1 1 1 1 KH domain MDM31_MDM32 PF08118.11 KKK21177.1 - 1e-253 842.8 0.0 2e-253 841.8 0.0 1.5 1 1 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins HCNGP PF07818.13 KKK21178.1 - 3.5e-29 101.3 0.4 6.5e-29 100.4 0.4 1.4 1 0 0 1 1 1 1 HCNGP-like protein Proteasome PF00227.26 KKK21179.1 - 1.5e-33 115.9 0.0 8.9e-33 113.4 0.1 1.9 2 0 0 2 2 2 1 Proteasome subunit DUF974 PF06159.13 KKK21179.1 - 0.2 11.4 0.0 0.27 11.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF974) FAA_hydrolase PF01557.18 KKK21180.1 - 4.2e-64 216.2 0.0 5.2e-64 215.9 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family GspH PF12019.8 KKK21180.1 - 0.02 15.3 0.2 0.034 14.6 0.2 1.3 1 0 0 1 1 1 0 Type II transport protein GspH zinc_ribbon_10 PF10058.9 KKK21186.1 - 1.3e-19 69.6 0.1 2.3e-19 68.9 0.1 1.4 1 0 0 1 1 1 1 Predicted integral membrane zinc-ribbon metal-binding protein Rubredoxin_2 PF18073.1 KKK21186.1 - 1.6 8.5 6.3 3.8 7.3 6.3 1.6 1 0 0 1 1 1 0 Rubredoxin metal binding domain Abhydrolase_3 PF07859.13 KKK21187.1 - 1.7e-42 145.7 0.0 2.2e-42 145.3 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KKK21187.1 - 2.4e-10 39.9 1.8 8.9e-10 38.0 1.8 1.7 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_6 PF12697.7 KKK21187.1 - 4.3e-05 24.2 0.6 6.2e-05 23.7 0.6 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family bZIP_1 PF00170.21 KKK21188.1 - 1e-09 38.3 10.0 7.1e-09 35.6 10.0 2.0 1 1 0 1 1 1 1 bZIP transcription factor PRKG1_interact PF15898.5 KKK21188.1 - 0.013 16.4 0.9 0.025 15.5 0.9 1.6 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain bZIP_2 PF07716.15 KKK21188.1 - 0.48 10.5 15.8 30 4.8 14.1 2.7 2 1 0 2 2 2 0 Basic region leucine zipper Ndc1_Nup PF09531.10 KKK21188.1 - 3.1 6.4 5.6 3.4 6.2 5.6 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Ribonuclease_3 PF00636.26 KKK21189.1 - 1.4e-28 99.6 0.1 1.8e-15 57.4 0.0 3.8 3 1 1 4 4 4 2 Ribonuclease III domain Dicer_dimer PF03368.14 KKK21189.1 - 1.1e-21 76.8 0.0 2.7e-21 75.5 0.0 1.7 1 0 0 1 1 1 1 Dicer dimerisation domain Ribonucleas_3_3 PF14622.6 KKK21189.1 - 8.8e-21 74.4 0.5 7.7e-10 39.0 0.0 4.5 3 1 0 4 4 4 2 Ribonuclease-III-like DEAD PF00270.29 KKK21189.1 - 1.1e-17 64.4 0.0 2.3e-17 63.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KKK21189.1 - 7e-15 55.3 0.0 2.1e-14 53.8 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KKK21189.1 - 2.6e-09 37.3 0.0 5.4e-05 23.3 0.0 2.4 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit GMC_oxred_N PF00732.19 KKK21190.1 - 8.7e-52 176.3 0.0 1.2e-51 175.9 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KKK21190.1 - 3e-31 108.9 0.1 5.2e-31 108.1 0.1 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 KKK21190.1 - 2.1e-06 27.1 0.0 3.1e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 KKK21190.1 - 0.00013 22.1 0.1 0.00029 21.0 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KKK21190.1 - 0.00031 20.4 0.3 0.0014 18.3 0.3 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KKK21190.1 - 0.0025 17.1 0.0 0.0083 15.4 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KKK21190.1 - 0.0039 16.5 0.0 0.76 9.0 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KKK21190.1 - 0.01 15.0 0.0 0.8 8.7 0.0 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_binding_2 PF00890.24 KKK21190.1 - 0.014 14.5 0.0 0.024 13.8 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 KKK21190.1 - 0.046 12.4 0.0 0.14 10.9 0.0 1.7 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_9 PF13454.6 KKK21190.1 - 0.12 12.4 0.0 0.26 11.3 0.0 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding SR-25 PF10500.9 KKK21191.1 - 0.17 11.5 13.4 0.23 11.1 13.4 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Acetyltransf_7 PF13508.7 KKK21193.1 - 2.2e-05 24.8 0.0 4.8e-05 23.7 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KKK21193.1 - 2.3e-05 24.6 0.0 3.2e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 KKK21193.1 - 7.9e-05 22.8 0.0 0.00018 21.7 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KKK21193.1 - 0.022 15.4 0.0 0.028 15.1 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KKK21193.1 - 0.023 14.7 0.0 0.035 14.0 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Anoctamin PF04547.12 KKK21194.1 - 1e-117 393.8 4.2 1.3e-117 393.4 4.2 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel GST_N_2 PF13409.6 KKK21194.1 - 2.9e-18 65.9 0.0 6.6e-18 64.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KKK21194.1 - 1.4e-10 41.1 0.0 4e-10 39.6 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KKK21194.1 - 0.022 15.0 0.0 0.062 13.5 0.0 1.8 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain ECF_trnsprt PF12822.7 KKK21194.1 - 0.036 14.2 7.4 0.037 14.1 2.4 2.8 2 1 0 2 2 2 0 ECF transporter, substrate-specific component GST_C_6 PF17171.4 KKK21194.1 - 0.11 12.4 0.0 0.35 10.7 0.0 1.9 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Acetyltransf_1 PF00583.25 KKK21195.1 - 5.8e-14 52.3 0.0 1.5e-13 51.0 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family GRIP PF01465.20 KKK21195.1 - 1.8e-13 50.1 0.3 4.6e-13 48.8 0.3 1.7 1 0 0 1 1 1 1 GRIP domain GAS PF13851.6 KKK21195.1 - 1.6e-07 30.9 154.6 0.0012 18.3 13.9 10.7 2 2 7 9 9 9 7 Growth-arrest specific micro-tubule binding FR47 PF08445.10 KKK21195.1 - 1.3e-06 28.2 0.0 2.9e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 KKK21195.1 - 1.7e-06 28.3 0.0 3.7e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Spc7 PF08317.11 KKK21195.1 - 2.9e-06 26.4 154.5 0.023 13.6 13.8 8.0 2 2 4 7 7 7 4 Spc7 kinetochore protein Acetyltransf_10 PF13673.7 KKK21195.1 - 0.00036 20.5 0.0 0.0011 18.9 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DHR10 PF18595.1 KKK21195.1 - 0.0012 18.9 11.1 0.0012 18.9 11.1 12.2 4 3 5 11 11 9 3 Designed helical repeat protein 10 domain CALCOCO1 PF07888.11 KKK21195.1 - 0.0014 17.6 30.7 0.0014 17.6 30.7 4.9 2 2 3 5 5 4 1 Calcium binding and coiled-coil domain (CALCOCO1) like Filament PF00038.21 KKK21195.1 - 0.0015 18.2 43.5 0.0015 18.2 43.5 7.3 2 2 4 6 6 6 2 Intermediate filament protein Bap31_Bap29_C PF18035.1 KKK21195.1 - 0.0021 18.1 3.1 0.0021 18.1 3.1 11.6 11 3 0 11 11 7 2 Bap31/Bap29 cytoplasmic coiled-coil domain CENP-F_leu_zip PF10473.9 KKK21195.1 - 0.0024 17.9 27.5 0.0024 17.9 27.5 10.0 2 2 7 9 9 8 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 KASH_CCD PF14662.6 KKK21195.1 - 0.0068 16.3 20.1 0.0068 16.3 20.1 7.3 2 2 3 6 6 6 1 Coiled-coil region of CCDC155 or KASH Atg14 PF10186.9 KKK21195.1 - 0.71 8.9 134.5 0.0089 15.1 14.3 7.4 2 2 4 7 7 7 0 Vacuolar sorting 38 and autophagy-related subunit 14 Cep57_CLD PF14073.6 KKK21195.1 - 0.74 9.8 0.0 0.74 9.8 0.0 7.9 4 2 4 8 8 6 0 Centrosome localisation domain of Cep57 ATG16 PF08614.11 KKK21195.1 - 1.3 9.2 177.6 0.1 12.8 19.6 9.7 2 2 8 10 10 10 0 Autophagy protein 16 (ATG16) FPP PF05911.11 KKK21195.1 - 1.5 6.9 143.2 0.0047 15.2 17.6 6.2 1 1 5 6 6 6 0 Filament-like plant protein, long coiled-coil Fez1 PF06818.15 KKK21195.1 - 5.4 7.4 149.5 0.13 12.7 17.7 7.8 2 2 5 7 7 6 0 Fez1 ERM PF00769.19 KKK21195.1 - 5.5 6.7 175.9 0.19 11.5 31.3 7.1 2 2 4 6 6 5 0 Ezrin/radixin/moesin family Ank_4 PF13637.6 KKK21196.1 - 7.3e-25 87.0 0.3 9e-10 38.9 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KKK21196.1 - 7.5e-25 87.3 0.0 3.7e-14 53.1 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KKK21196.1 - 3.5e-17 62.3 1.4 7.3e-09 35.7 0.1 3.7 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 KKK21196.1 - 7.7e-17 60.9 1.6 0.0011 19.3 0.0 4.7 4 0 0 4 4 4 4 Ankyrin repeat Ank_3 PF13606.6 KKK21196.1 - 7.5e-14 50.5 0.6 0.0021 18.4 0.0 4.5 5 0 0 5 5 5 3 Ankyrin repeat cNMP_binding PF00027.29 KKK21197.1 - 3.1e-30 104.1 1.6 3.9e-19 68.5 0.0 5.6 5 1 1 6 6 6 4 Cyclic nucleotide-binding domain Patatin PF01734.22 KKK21197.1 - 2.6e-18 66.9 6.5 8.3e-17 62.0 6.5 2.7 1 1 0 1 1 1 1 Patatin-like phospholipase Copper-fist PF00649.18 KKK21198.1 - 3.3e-18 64.9 0.3 9.4e-18 63.4 0.3 1.9 1 0 0 1 1 1 1 Copper fist DNA binding domain RVT_1 PF00078.27 KKK21199.1 - 0.00024 20.7 0.0 0.0005 19.6 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Transp_cyt_pur PF02133.15 KKK21200.1 - 2.1e-150 501.3 32.4 2.5e-150 501.1 32.4 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Urb2 PF10441.9 KKK21201.1 - 2.6e-66 223.5 0.2 1.8e-65 220.7 0.0 2.6 2 0 0 2 2 2 1 Urb2/Npa2 family DUF543 PF04418.12 KKK21202.1 - 1.8e-27 95.2 0.0 2e-27 94.9 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF543) Lactamase_B_6 PF16661.5 KKK21205.1 - 2.6e-65 219.5 0.0 4.4e-65 218.7 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain CPSF100_C PF13299.6 KKK21205.1 - 8.9e-51 172.4 0.8 2.3e-50 171.1 0.0 2.1 2 0 0 2 2 2 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.8 KKK21205.1 - 2e-13 50.6 0.0 7.3e-13 48.8 0.0 2.0 2 0 0 2 2 2 1 Beta-Casp domain RMMBL PF07521.12 KKK21205.1 - 6.8e-12 45.2 0.0 4.7e-11 42.5 0.0 2.2 2 0 0 2 2 2 1 Zn-dependent metallo-hydrolase RNA specificity domain PGM_PMM_IV PF00408.20 KKK21205.1 - 0.092 12.9 0.1 0.4 10.9 0.0 2.1 2 0 0 2 2 2 0 Phosphoglucomutase/phosphomannomutase, C-terminal domain AA_permease_2 PF13520.6 KKK21206.1 - 5.5e-46 157.3 35.2 6.6e-46 157.0 35.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KKK21206.1 - 4.5e-13 48.6 27.0 5.9e-13 48.2 27.0 1.1 1 0 0 1 1 1 1 Amino acid permease DUF4690 PF15756.5 KKK21206.1 - 0.085 13.5 0.0 0.22 12.1 0.0 1.7 1 0 0 1 1 1 0 Small Novel Rich in Cartilage DUF2721 PF11026.8 KKK21206.1 - 0.8 9.6 0.0 0.8 9.6 0.0 4.0 4 2 1 5 5 5 0 Protein of unknown function (DUF2721) Frag1 PF10277.9 KKK21207.1 - 2.4e-37 128.6 9.8 2.4e-37 128.6 9.8 2.9 3 0 0 3 3 3 1 Frag1/DRAM/Sfk1 family DUF805 PF05656.14 KKK21207.1 - 4.6 7.7 0.0 4.6 7.7 0.0 4.3 4 0 0 4 4 4 0 Protein of unknown function (DUF805) Glyco_hydro_32N PF00251.20 KKK21208.1 - 3.5e-96 322.4 3.1 4.5e-96 322.0 3.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 KKK21208.1 - 2.4e-37 128.3 0.4 2.4e-37 128.3 0.4 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 32 C terminal Sortilin-Vps10 PF15902.5 KKK21208.1 - 0.0051 15.6 0.6 0.033 13.0 0.1 2.0 2 0 0 2 2 2 1 Sortilin, neurotensin receptor 3, BNR PF02012.20 KKK21208.1 - 0.011 15.6 0.7 0.075 13.1 0.7 2.6 1 0 0 1 1 1 0 BNR/Asp-box repeat CHB_HEX_C PF03174.13 KKK21208.1 - 0.031 14.3 0.2 0.081 12.9 0.2 1.7 1 0 0 1 1 1 0 Chitobiase/beta-hexosaminidase C-terminal domain BNR_2 PF13088.6 KKK21208.1 - 0.068 12.5 1.5 0.5 9.6 1.5 2.0 1 1 0 1 1 1 0 BNR repeat-like domain SR-25 PF10500.9 KKK21208.1 - 7.3 6.1 17.6 0.27 10.8 7.7 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein RF-1 PF00472.20 KKK21209.1 - 1.1e-18 67.2 0.5 1.6e-18 66.7 0.5 1.1 1 0 0 1 1 1 1 RF-1 domain U3_assoc_6 PF08640.11 KKK21210.1 - 1.5e-30 105.1 0.7 3.5e-30 103.9 0.7 1.6 1 0 0 1 1 1 1 U3 small nucleolar RNA-associated protein 6 TPR_14 PF13428.6 KKK21210.1 - 0.0015 19.2 0.2 0.21 12.5 0.1 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat RRM_1 PF00076.22 KKK21212.1 - 1.5e-09 37.6 0.0 2.8e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KKK21212.1 - 0.0073 15.9 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SYS1 PF09801.9 KKK21213.1 - 4.1e-49 166.5 11.5 8.7e-49 165.4 11.5 1.5 1 1 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network COX6B PF02297.17 KKK21214.1 - 4.2e-23 81.4 5.1 6.7e-23 80.7 5.1 1.3 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb Abi_2 PF07751.11 KKK21214.1 - 0.045 14.0 0.3 0.076 13.3 0.3 1.3 1 0 0 1 1 1 0 Abi-like protein Pet191_N PF10203.9 KKK21214.1 - 0.056 13.8 1.2 0.11 12.9 1.2 1.4 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 Sec23_trunk PF04811.15 KKK21216.1 - 5.3e-57 193.2 0.0 8.7e-57 192.5 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 KKK21216.1 - 9.3e-25 86.4 0.0 2.2e-24 85.2 0.0 1.7 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 KKK21216.1 - 8.6e-18 64.9 0.0 1.6e-17 64.0 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 KKK21216.1 - 3.2e-16 59.1 6.2 6.1e-16 58.2 6.2 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 KKK21216.1 - 2e-06 27.6 0.0 4e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat SLS PF14611.6 KKK21216.1 - 0.0039 17.1 0.0 0.0073 16.1 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial inner-membrane-bound regulator DUF1678 PF07913.11 KKK21216.1 - 0.059 13.1 0.1 0.12 12.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1678) Fungal_trans_2 PF11951.8 KKK21217.1 - 4.2e-65 220.0 0.0 4.8e-65 219.8 0.0 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain Aldolase_II PF00596.21 KKK21218.1 - 1.2e-41 142.7 0.1 2.6e-41 141.6 0.1 1.5 1 1 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain COG5 PF10392.9 KKK21219.1 - 8.1e-41 139.3 3.7 2.3e-40 137.9 0.2 2.7 3 0 0 3 3 3 1 Golgi transport complex subunit 5 CENP-F_leu_zip PF10473.9 KKK21219.1 - 0.089 12.8 1.0 0.27 11.3 0.3 2.0 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 APH PF01636.23 KKK21219.1 - 0.11 12.4 0.5 0.51 10.2 0.2 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family PhyH PF05721.13 KKK21255.1 - 1.4e-07 32.0 0.0 4.4e-06 27.1 0.0 2.5 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Het-C PF07217.11 KKK21256.1 - 2e-281 934.5 0.0 3.2e-281 933.8 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C TctA PF01970.16 KKK21256.1 - 0.051 12.3 0.0 0.085 11.6 0.0 1.3 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctA family IBN_N PF03810.19 KKK21257.1 - 6.4e-11 42.0 0.1 1.2e-08 34.8 0.0 4.0 2 1 1 3 3 3 1 Importin-beta N-terminal domain RIX1 PF08167.12 KKK21257.1 - 1.2e-05 25.1 4.9 7.5e-05 22.5 0.2 4.0 4 0 0 4 4 4 1 rRNA processing/ribosome biogenesis Xpo1 PF08389.12 KKK21257.1 - 0.00048 20.2 0.8 0.043 13.9 0.0 4.1 5 0 0 5 5 5 1 Exportin 1-like protein Proteasom_PSMB PF10508.9 KKK21257.1 - 0.0016 17.0 0.3 0.0087 14.6 0.0 2.3 3 0 0 3 3 3 1 Proteasome non-ATPase 26S subunit Cnd3 PF12719.7 KKK21257.1 - 0.0018 17.5 0.4 0.21 10.7 0.5 3.0 2 1 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain CAS_CSE1 PF03378.15 KKK21257.1 - 0.016 13.7 0.0 0.043 12.3 0.0 1.6 1 0 0 1 1 1 0 CAS/CSE protein, C-terminus RICTOR_N PF14664.6 KKK21257.1 - 0.094 11.7 2.1 0.11 11.4 0.8 1.8 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR, N-term HEAT_EZ PF13513.6 KKK21257.1 - 0.25 11.9 10.8 3.1 8.4 0.3 5.3 5 0 0 5 5 5 0 HEAT-like repeat Methyltransf_23 PF13489.6 KKK21258.1 - 1.7e-24 86.6 0.0 2.3e-24 86.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKK21258.1 - 1e-11 45.4 0.0 2.7e-11 44.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KKK21258.1 - 1.1e-10 42.1 0.0 4.2e-10 40.3 0.0 1.9 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KKK21258.1 - 2.2e-09 37.3 0.0 1.1e-08 35.0 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KKK21258.1 - 6.7e-09 36.3 0.0 1.3e-08 35.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KKK21258.1 - 0.0031 16.8 0.0 0.0082 15.5 0.0 1.7 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_16 PF10294.9 KKK21258.1 - 0.0032 17.2 0.0 0.0054 16.5 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_4 PF02390.17 KKK21258.1 - 0.005 16.3 0.0 0.019 14.4 0.0 1.8 2 0 0 2 2 2 1 Putative methyltransferase MTS PF05175.14 KKK21258.1 - 0.0065 16.0 0.0 0.029 13.9 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase small domain PrmA PF06325.13 KKK21258.1 - 0.015 14.7 0.0 0.021 14.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_2 PF00891.18 KKK21258.1 - 0.039 13.2 0.0 0.065 12.5 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase domain DUF938 PF06080.12 KKK21258.1 - 0.11 12.3 0.0 0.44 10.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF938) DUF5600 PF18150.1 KKK21258.1 - 0.15 12.7 0.0 0.43 11.2 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5600) IBR PF01485.21 KKK21259.1 - 7.9e-06 26.0 8.1 7.9e-06 26.0 8.1 3.5 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain HORMA PF02301.18 KKK21260.1 - 3.9e-10 39.7 0.0 5.1e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 HORMA domain Dcc1 PF09724.9 KKK21261.1 - 4.7e-20 72.2 0.0 1.9e-19 70.2 0.0 1.9 1 1 0 1 1 1 1 Sister chromatid cohesion protein Dcc1 RNA_pol_3_Rpc31 PF11705.8 KKK21261.1 - 0.0085 16.4 4.3 0.016 15.5 4.3 1.5 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 DUF4611 PF15387.6 KKK21261.1 - 0.02 15.1 4.5 0.043 14.0 4.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) RXT2_N PF08595.11 KKK21261.1 - 0.053 13.6 5.7 0.087 12.8 5.7 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal FAM176 PF14851.6 KKK21261.1 - 0.1 12.3 2.2 0.2 11.3 2.2 1.5 1 0 0 1 1 1 0 FAM176 family NOA36 PF06524.12 KKK21261.1 - 0.46 9.8 9.8 0.71 9.1 9.8 1.2 1 0 0 1 1 1 0 NOA36 protein CENP-B_dimeris PF09026.10 KKK21261.1 - 0.58 10.6 13.5 1.4 9.4 13.5 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DNA_pol_phi PF04931.13 KKK21261.1 - 0.98 7.4 7.3 1.4 7.0 7.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi DUF2457 PF10446.9 KKK21261.1 - 1.8 7.6 13.0 3.8 6.6 13.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) SH3_4 PF06347.13 KKK21261.1 - 2.2 8.2 5.6 0.41 10.5 0.2 2.7 3 1 0 3 3 3 0 Bacterial SH3 domain WRNPLPNID PF15017.6 KKK21261.1 - 3.8 8.5 13.3 2.6 9.0 10.2 2.1 2 0 0 2 2 2 0 Putative WW-binding domain and destruction box Cwf_Cwc_15 PF04889.12 KKK21261.1 - 6.6 6.4 15.4 0.081 12.7 7.5 1.7 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Acetyltransf_7 PF13508.7 KKK21262.1 - 3.6e-06 27.3 0.0 6.8e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KKK21262.1 - 0.00018 21.7 0.1 0.00048 20.3 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 KKK21262.1 - 0.00027 21.0 0.1 0.0016 18.5 0.0 2.2 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KKK21262.1 - 0.0032 17.4 0.1 0.017 15.1 0.0 2.2 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_10 PF13673.7 KKK21262.1 - 0.0034 17.3 0.0 0.0074 16.2 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF5490 PF17593.2 KKK21262.1 - 0.038 14.0 1.1 0.088 12.8 1.1 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5490) Acetyltransf_15 PF17013.5 KKK21262.1 - 0.043 13.3 0.0 0.056 12.9 0.0 1.2 1 0 0 1 1 1 0 Putative acetyl-transferase zf-TRAF PF02176.18 KKK21263.1 - 4.8e-12 46.4 8.9 9.5e-10 39.0 4.7 4.5 2 2 3 5 5 5 3 TRAF-type zinc finger zf-TRAF_2 PF15965.5 KKK21263.1 - 3.7e-07 30.5 9.3 3.7e-07 30.5 9.3 3.5 1 1 3 4 4 4 2 TRAF-like zinc-finger zf-C3HC4 PF00097.25 KKK21263.1 - 3.9e-07 29.8 11.9 3.9e-07 29.8 11.9 3.3 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KKK21263.1 - 7.2e-07 29.1 10.7 7.2e-07 29.1 10.7 2.6 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 KKK21263.1 - 3.8e-06 26.8 11.5 3.8e-06 26.8 11.5 3.3 3 1 0 3 3 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KKK21263.1 - 1.1e-05 25.5 12.1 1.1e-05 25.5 12.1 2.8 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 KKK21263.1 - 2.3e-05 24.6 13.0 2.3e-05 24.6 13.0 3.7 2 1 1 3 3 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 KKK21263.1 - 5.4e-05 23.0 10.0 5.4e-05 23.0 10.0 3.5 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) Sina PF03145.16 KKK21263.1 - 0.0007 19.6 17.9 0.0082 16.1 5.0 3.1 1 1 3 4 4 4 3 Seven in absentia protein family zf-C3HC4_2 PF13923.6 KKK21263.1 - 0.0011 18.7 12.5 0.0011 18.7 12.5 4.0 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) PilN PF05137.13 KKK21263.1 - 0.032 14.3 0.1 0.073 13.2 0.1 1.5 1 0 0 1 1 1 0 Fimbrial assembly protein (PilN) zf-ACC PF17848.1 KKK21263.1 - 0.036 14.1 0.1 0.036 14.1 0.1 4.0 4 0 0 4 4 4 0 Acetyl-coA carboxylase zinc finger domain SNARE PF05739.19 KKK21264.1 - 1e-08 35.0 0.9 1e-08 35.0 0.9 1.9 2 0 0 2 2 2 1 SNARE domain Use1 PF09753.9 KKK21264.1 - 8.2e-05 22.5 0.0 0.00018 21.3 0.0 1.5 1 1 0 1 1 1 1 Membrane fusion protein Use1 MDMPI_N PF11716.8 KKK21264.1 - 0.0068 17.1 0.1 0.018 15.7 0.1 1.7 1 0 0 1 1 1 1 Mycothiol maleylpyruvate isomerase N-terminal domain TPR_MLP1_2 PF07926.12 KKK21264.1 - 0.068 13.2 0.4 0.068 13.2 0.4 2.2 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF1664 PF07889.12 KKK21264.1 - 0.26 11.4 2.0 8.3 6.5 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Snapin_Pallidin PF14712.6 KKK21264.1 - 0.41 11.1 2.5 2.3 8.7 0.3 2.3 2 0 0 2 2 2 0 Snapin/Pallidin WXG100 PF06013.12 KKK21264.1 - 0.43 10.9 3.3 12 6.2 0.1 3.5 3 1 1 4 4 4 0 Proteins of 100 residues with WXG CENP-Q PF13094.6 KKK21264.1 - 2.1 8.5 8.2 0.78 9.9 0.3 2.6 2 2 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Golgin_A5 PF09787.9 KKK21264.1 - 2.3 7.6 6.4 1.2 8.5 0.5 2.1 2 0 0 2 2 2 0 Golgin subfamily A member 5 TolA_bind_tri PF16331.5 KKK21264.1 - 8.4 6.6 13.5 9.4 6.4 2.8 3.3 2 2 1 4 4 4 0 TolA binding protein trimerisation Anp1 PF03452.14 KKK21265.1 - 6.8e-114 379.7 0.0 1e-113 379.1 0.0 1.3 1 0 0 1 1 1 1 Anp1 adh_short PF00106.25 KKK21265.1 - 1e-09 38.1 0.0 1.8e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KKK21265.1 - 3.9e-06 26.9 0.0 6.8e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 KR domain Glyco_tranf_2_4 PF13704.6 KKK21265.1 - 0.018 15.5 0.1 0.056 14.0 0.1 1.9 1 0 0 1 1 1 0 Glycosyl transferase family 2 FAD_binding_4 PF01565.23 KKK21266.1 - 8.7e-21 74.1 0.8 2.3e-20 72.8 0.8 1.8 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KKK21266.1 - 3e-08 33.6 0.2 6.6e-08 32.5 0.2 1.6 1 0 0 1 1 1 1 Berberine and berberine like Asp PF00026.23 KKK21268.1 - 1.5e-62 211.9 8.2 1.8e-62 211.6 8.2 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KKK21268.1 - 4.2e-09 36.9 2.3 0.00087 19.6 0.1 2.9 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KKK21268.1 - 0.00083 19.9 0.2 1.2 9.8 0.0 2.7 2 0 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 KKK21268.1 - 0.0052 17.3 1.2 2.8 8.6 0.1 2.9 2 1 0 2 2 2 2 gag-polyprotein putative aspartyl protease ParA PF10609.9 KKK21269.1 - 6.4e-96 320.6 0.0 7.4e-96 320.3 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 KKK21269.1 - 4.2e-06 26.8 0.0 1.6e-05 25.0 0.0 1.9 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.15 KKK21269.1 - 1.7e-05 24.1 2.2 0.00038 19.7 0.5 2.6 1 1 1 3 3 3 1 Anion-transporting ATPase AAA_31 PF13614.6 KKK21269.1 - 2.4e-05 24.4 0.0 0.00012 22.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_26 PF13500.6 KKK21269.1 - 0.017 15.0 0.0 0.8 9.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 KKK21269.1 - 0.017 15.0 0.0 0.035 14.0 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase MipZ PF09140.11 KKK21269.1 - 0.073 12.3 0.0 0.19 11.0 0.0 1.6 1 1 0 1 1 1 0 ATPase MipZ CLP1_P PF16575.5 KKK21269.1 - 0.078 12.8 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop TsaE PF02367.17 KKK21269.1 - 0.096 12.7 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 KKK21269.1 - 0.1 12.3 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KKK21269.1 - 0.15 11.6 0.0 0.27 10.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain PEMT PF04191.13 KKK21270.1 - 5.1e-58 194.0 8.0 1.1e-35 122.2 1.1 2.7 2 0 0 2 2 2 2 Phospholipid methyltransferase SKICH PF17751.1 KKK21270.1 - 0.0077 16.8 0.1 0.24 12.0 0.1 2.4 1 1 0 1 1 1 1 SKICH domain HECW_N PF16562.5 KKK21270.1 - 0.013 15.3 0.1 0.049 13.4 0.1 1.8 2 0 0 2 2 2 0 N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2 RNase_PH PF01138.21 KKK21271.1 - 3.3e-32 111.8 0.0 7.3e-32 110.6 0.0 1.6 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 HTH_AsnC-type PF13404.6 KKK21272.1 - 0.04 13.7 0.0 0.065 13.1 0.0 1.3 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain Cyclin_N PF00134.23 KKK21273.1 - 6.4e-11 42.1 0.0 1.3e-10 41.1 0.0 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C_2 PF16899.5 KKK21273.1 - 0.021 15.2 1.0 0.098 13.0 0.2 2.4 2 1 0 2 2 2 0 Cyclin C-terminal domain DUF4452 PF14618.6 KKK21274.1 - 4.1e-77 257.8 7.4 5.1e-77 257.5 7.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4452) GST_N_2 PF13409.6 KKK21275.1 - 9.3e-22 77.1 0.0 2.4e-21 75.8 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KKK21275.1 - 9.4e-18 64.0 0.0 1.7e-17 63.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KKK21275.1 - 1.2e-06 28.8 0.0 6.7e-05 23.2 0.0 2.4 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KKK21275.1 - 4.1e-05 23.7 0.0 9.9e-05 22.5 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KKK21275.1 - 0.0047 17.1 0.0 0.011 15.9 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 KKK21275.1 - 0.14 12.8 0.0 0.22 12.1 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Mito_carr PF00153.27 KKK21276.1 - 1.2e-68 227.1 3.4 7.2e-23 80.3 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_1 PF00036.32 KKK21276.1 - 7.5e-21 72.1 2.6 2.8e-06 26.5 0.1 3.6 3 0 0 3 3 3 3 EF hand EF-hand_5 PF13202.6 KKK21276.1 - 2.2e-19 68.0 3.3 3.9e-06 26.1 0.2 3.6 3 1 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 KKK21276.1 - 5.9e-18 65.1 2.2 1.4e-11 44.7 0.2 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KKK21276.1 - 9e-15 53.3 7.9 0.00024 20.8 0.0 4.0 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 KKK21276.1 - 3.4e-10 39.6 0.7 0.00018 21.3 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KKK21276.1 - 8.2e-07 29.3 0.0 0.0024 18.2 0.0 2.3 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.6 KKK21276.1 - 0.061 13.2 0.6 11 5.9 0.0 2.8 3 0 0 3 3 3 0 EF hand GCP_N_terminal PF17681.1 KKK21277.1 - 1.1e-37 130.4 0.0 1.8e-37 129.6 0.0 1.3 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 KKK21277.1 - 2.6e-20 73.1 0.0 8e-20 71.5 0.0 1.8 1 1 0 1 1 1 1 Gamma tubulin complex component C-terminal Sec66 PF09802.9 KKK21277.1 - 0.064 12.8 0.4 0.12 12.0 0.4 1.4 1 0 0 1 1 1 0 Preprotein translocase subunit Sec66 ThiF PF00899.21 KKK21278.1 - 4.9e-112 373.2 0.0 7.5e-75 251.4 0.0 2.4 2 1 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 KKK21278.1 - 1e-94 317.2 0.2 3.1e-94 315.6 0.1 2.0 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site E1_UFD PF09358.10 KKK21278.1 - 1.6e-30 105.7 0.1 3.7e-30 104.5 0.1 1.7 1 0 0 1 1 1 1 Ubiquitin fold domain E1_FCCH PF16190.5 KKK21278.1 - 3.3e-29 100.9 0.2 7e-29 99.8 0.2 1.6 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain E1_4HB PF16191.5 KKK21278.1 - 6.8e-25 87.0 2.9 1e-24 86.5 0.8 2.5 3 0 0 3 3 3 1 Ubiquitin-activating enzyme E1 four-helix bundle Pkinase PF00069.25 KKK21278.1 - 6.6e-15 55.2 0.0 1.2e-14 54.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK21278.1 - 7.2e-12 45.1 0.0 1.7e-11 43.9 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase MFS_1 PF07690.16 KKK21279.1 - 1.1e-30 106.8 26.2 1.1e-30 106.8 26.2 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily adh_short_C2 PF13561.6 KKK21280.1 - 1.9e-55 188.0 3.0 2.3e-55 187.7 3.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KKK21280.1 - 3.7e-49 166.8 1.2 4.6e-49 166.5 1.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KKK21280.1 - 1.3e-13 51.3 1.8 2e-13 50.7 1.8 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KKK21280.1 - 2.3e-07 30.5 1.0 4.7e-07 29.5 1.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KKK21280.1 - 0.0015 18.0 0.2 0.0022 17.5 0.2 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Hexokinase_1 PF00349.21 KKK21281.1 - 1.9e-59 200.9 0.0 2.8e-59 200.4 0.0 1.3 1 0 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.16 KKK21281.1 - 2.6e-47 161.3 0.0 1.6e-46 158.7 0.0 2.0 1 1 0 1 1 1 1 Hexokinase GILT PF03227.16 KKK21282.1 - 4.2e-14 52.7 0.4 9.9e-14 51.5 0.3 1.7 1 1 0 1 1 1 1 Gamma interferon inducible lysosomal thiol reductase (GILT) TFIIA_gamma_C PF02751.14 KKK21284.1 - 8.7e-26 89.8 2.2 1.6e-25 89.0 2.2 1.4 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit TFIIA_gamma_N PF02268.16 KKK21284.1 - 2.8e-24 84.9 0.2 3.8e-24 84.4 0.2 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain Glyco_hydro_17 PF00332.18 KKK21312.1 - 1.2e-09 38.2 4.9 1.5e-06 28.0 1.7 2.2 1 1 1 2 2 2 2 Glycosyl hydrolases family 17 PHD PF00628.29 KKK21314.1 - 2.7e-09 36.8 2.6 6.1e-09 35.6 2.6 1.6 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 KKK21314.1 - 0.0043 16.6 3.3 0.0068 15.9 3.3 1.3 1 0 0 1 1 1 1 PHD-finger UIM PF02809.20 KKK21314.1 - 0.028 14.3 2.4 0.028 14.3 2.4 2.4 2 0 0 2 2 2 0 Ubiquitin interaction motif zf-CW PF07496.15 KKK21314.1 - 0.22 11.5 1.6 0.59 10.2 1.6 1.7 1 0 0 1 1 1 0 CW-type Zinc Finger eIF-5a PF01287.20 KKK21315.1 - 7.9e-05 22.7 0.0 0.00016 21.7 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold SRR1 PF07985.12 KKK21317.1 - 1.8e-20 72.7 0.1 4.9e-20 71.3 0.0 1.8 2 0 0 2 2 2 1 SRR1 TrkH PF02386.16 KKK21325.1 - 5.3e-87 292.4 2.9 5.3e-87 292.4 2.9 1.7 2 0 0 2 2 2 1 Cation transport protein DUF4436 PF14494.6 KKK21325.1 - 0.35 10.1 1.4 0.59 9.4 1.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4436) MoaC PF01967.21 KKK21326.1 - 1.3e-45 154.8 0.2 2.3e-45 154.0 0.2 1.4 1 0 0 1 1 1 1 MoaC family Mob_synth_C PF06463.13 KKK21326.1 - 2.6e-38 130.8 0.0 4.2e-37 126.9 0.0 2.3 2 0 0 2 2 2 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.21 KKK21326.1 - 1.3e-26 93.9 0.0 2.3e-26 93.2 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 KKK21326.1 - 4.6e-05 23.7 0.0 0.00012 22.3 0.0 1.7 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 KKK21326.1 - 0.032 14.4 0.2 0.19 11.9 0.0 2.3 2 1 0 2 2 2 0 4Fe-4S single cluster domain Pyr_redox_dim PF02852.22 KKK21327.1 - 7.2e-34 116.4 0.1 8.4e-34 116.1 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Glyco_hydro_16 PF00722.21 KKK21328.1 - 1.3e-43 148.5 1.6 1.3e-43 148.5 1.6 2.3 2 1 0 2 2 2 1 Glycosyl hydrolases family 16 Hira PF07569.11 KKK21328.1 - 0.76 9.5 6.2 1.3 8.6 6.2 1.3 1 0 0 1 1 1 0 TUP1-like enhancer of split Syntaxin-6_N PF09177.11 KKK21329.1 - 0.03 14.9 0.5 0.61 10.7 0.1 2.6 2 0 0 2 2 2 0 Syntaxin 6, N-terminal Baculo_PEP_C PF04513.12 KKK21329.1 - 0.047 13.7 0.4 10 6.1 0.0 2.4 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DASH_Dad2 PF08654.10 KKK21329.1 - 0.061 13.8 0.3 3 8.3 0.0 2.6 2 0 0 2 2 2 0 DASH complex subunit Dad2 Methyltransf_15 PF09445.10 KKK21329.1 - 0.09 12.3 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase NPV_P10 PF05531.12 KKK21329.1 - 0.56 10.7 3.4 3.6 8.1 0.5 3.2 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Noc2 PF03715.13 KKK21330.1 - 1.8e-127 424.7 0.2 4.3e-127 423.5 0.2 1.7 1 0 0 1 1 1 1 Noc2p family Nop14 PF04147.12 KKK21330.1 - 0.01 14.1 0.0 0.01 14.1 0.0 3.2 2 1 0 3 3 3 0 Nop14-like family VPS28 PF03997.12 KKK21331.1 - 3e-73 245.5 0.0 3.6e-73 245.3 0.0 1.1 1 0 0 1 1 1 1 VPS28 protein Sugar_tr PF00083.24 KKK21332.1 - 1.3e-86 291.2 17.7 1.5e-86 291.0 17.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKK21332.1 - 5.6e-18 65.0 21.0 5.6e-18 65.0 21.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Dynein_AAA_lid PF17852.1 KKK21332.1 - 0.91 9.6 0.0 0.91 9.6 0.0 2.6 3 1 1 4 4 4 0 Dynein heavy chain AAA lid domain tRNA-synt_2b PF00587.25 KKK21333.1 - 1.4e-33 116.4 0.0 2.4e-33 115.6 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Fungal_trans PF04082.18 KKK21333.1 - 1.4e-25 89.8 1.0 2.4e-25 89.1 1.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain HGTP_anticodon PF03129.20 KKK21333.1 - 0.00011 22.3 0.0 0.00023 21.3 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain Glyco_hydro_31 PF01055.26 KKK21334.1 - 2.3e-158 528.0 2.2 2.9e-158 527.7 2.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 KKK21334.1 - 4.8e-34 117.0 0.0 8.7e-34 116.2 0.0 1.4 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 KKK21334.1 - 3.9e-14 52.7 2.5 3.9e-14 52.7 2.5 2.1 2 0 0 2 2 2 1 Galactose mutarotase-like Amidohydro_2 PF04909.14 KKK21335.1 - 8.5e-29 101.2 0.0 1.1e-28 100.9 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase ATP-synt_G PF04718.15 KKK21336.1 - 5.5e-36 123.4 0.3 9.3e-36 122.7 0.0 1.5 2 0 0 2 2 2 1 Mitochondrial ATP synthase g subunit ADH_N PF08240.12 KKK21337.1 - 1.2e-27 95.9 1.2 2.2e-27 95.1 1.2 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KKK21337.1 - 6.9e-14 52.0 0.0 1e-13 51.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KKK21337.1 - 4.3e-05 23.1 1.4 0.046 13.2 0.9 3.2 2 1 0 2 2 2 2 Glucose dehydrogenase C-terminus Methyltransf_16 PF10294.9 KKK21338.1 - 2e-20 73.2 0.0 3.8e-20 72.3 0.0 1.4 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_25 PF13649.6 KKK21338.1 - 0.084 13.6 0.0 0.27 12.0 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain DEAD PF00270.29 KKK21339.1 - 1.7e-25 89.8 0.0 9.4e-25 87.4 0.0 2.1 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KKK21339.1 - 9.1e-24 83.9 0.0 3e-23 82.3 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KKK21339.1 - 1.4e-05 25.1 0.1 0.00012 22.1 0.0 2.4 2 1 1 3 3 3 1 Type III restriction enzyme, res subunit PNP_UDP_1 PF01048.20 KKK21342.1 - 5.8e-13 48.6 0.0 1e-12 47.8 0.0 1.4 1 0 0 1 1 1 1 Phosphorylase superfamily Pkinase PF00069.25 KKK21343.1 - 6.7e-05 22.4 0.0 0.00013 21.4 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK21343.1 - 0.003 16.9 0.0 0.0076 15.6 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Dopey_N PF04118.14 KKK21343.1 - 0.012 14.8 0.1 0.019 14.1 0.1 1.3 1 0 0 1 1 1 0 Dopey, N-terminal P4Ha_N PF08336.11 KKK21343.1 - 0.073 13.1 0.2 0.15 12.0 0.2 1.5 1 0 0 1 1 1 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Pkinase PF00069.25 KKK21344.1 - 1.6e-48 165.4 0.0 2e-48 165.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK21344.1 - 1.2e-27 96.8 0.0 1.8e-27 96.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KKK21344.1 - 0.0078 15.6 0.0 0.018 14.4 0.0 1.5 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KKK21344.1 - 0.013 14.5 0.0 0.02 13.8 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain DUF4291 PF14124.6 KKK21346.1 - 2e-70 236.3 0.1 2.4e-70 236.1 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4291) Methyltransf_23 PF13489.6 KKK21347.1 - 3.2e-21 75.9 0.0 4.8e-21 75.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KKK21347.1 - 9.7e-11 41.7 0.0 2.2e-09 37.3 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKK21347.1 - 9.9e-10 39.0 0.0 3e-09 37.4 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KKK21347.1 - 1.1e-05 26.0 0.0 2.7e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KKK21347.1 - 1.2e-05 26.0 0.0 8.1e-05 23.3 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KKK21347.1 - 0.0022 17.4 0.0 1.4 8.2 0.0 2.7 2 1 0 2 2 2 2 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 KKK21347.1 - 0.004 16.6 0.0 0.025 14.0 0.0 2.1 2 0 0 2 2 2 1 Putative methyltransferase RRN9 PF10680.9 KKK21347.1 - 0.029 14.6 0.1 2.7 8.3 0.1 2.4 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor MTS PF05175.14 KKK21347.1 - 0.088 12.4 0.0 0.22 11.1 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_16 PF10294.9 KKK21347.1 - 0.13 12.0 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase PrmA PF06325.13 KKK21347.1 - 0.18 11.2 0.0 0.31 10.4 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DUF2406 PF10295.9 KKK21348.1 - 3.7e-20 72.4 1.5 4.1e-20 72.2 0.3 1.6 2 0 0 2 2 2 1 Uncharacterised protein (DUF2406) Glyco_hydro_72 PF03198.14 KKK21349.1 - 2.6e-136 454.0 12.6 3.3e-136 453.7 12.6 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.13 KKK21349.1 - 9.8e-26 90.3 7.0 1.1e-25 90.1 5.0 2.2 2 0 0 2 2 2 1 X8 domain Gly_transf_sug PF04488.15 KKK21350.1 - 2.4e-13 50.5 0.1 4.3e-13 49.7 0.1 1.3 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.7 KKK21350.1 - 0.094 12.0 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain Cupin_3 PF05899.12 KKK21351.1 - 0.033 13.9 0.0 0.047 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF861) ABC_tran PF00005.27 KKK21352.1 - 1.1e-46 158.7 0.0 2.9e-28 99.1 0.0 3.0 2 1 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KKK21352.1 - 1.9e-38 132.7 8.9 1.7e-23 83.6 2.3 2.9 2 1 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 KKK21352.1 - 7.6e-10 38.6 0.4 0.098 12.1 0.0 4.2 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 KKK21352.1 - 2.7e-05 24.1 0.0 0.061 13.2 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase DUF87 PF01935.17 KKK21352.1 - 0.00016 21.8 2.8 0.21 11.6 0.0 3.2 3 0 0 3 3 3 2 Helicase HerA, central domain AAA_23 PF13476.6 KKK21352.1 - 0.00016 22.2 0.1 0.028 14.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 KKK21352.1 - 0.00059 19.9 0.1 0.11 12.6 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_29 PF13555.6 KKK21352.1 - 0.00095 18.9 0.2 0.99 9.2 0.1 2.9 3 0 0 3 3 2 1 P-loop containing region of AAA domain AAA_22 PF13401.6 KKK21352.1 - 0.0017 18.7 0.0 5.5 7.3 0.0 3.4 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 KKK21352.1 - 0.0021 18.5 1.4 0.14 12.5 0.1 3.0 3 0 0 3 3 2 1 AAA ATPase domain T2SSE PF00437.20 KKK21352.1 - 0.0035 16.4 0.0 0.7 8.9 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein DUF2275 PF10039.9 KKK21352.1 - 0.022 14.9 0.1 0.054 13.6 0.1 1.6 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2275) DUF2075 PF09848.9 KKK21352.1 - 0.028 13.7 0.0 0.41 9.8 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Zeta_toxin PF06414.12 KKK21352.1 - 0.042 13.1 0.1 2.4 7.4 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin IstB_IS21 PF01695.17 KKK21352.1 - 0.062 13.0 0.2 2.9 7.6 0.0 3.0 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_7 PF12775.7 KKK21352.1 - 0.066 12.7 0.1 7.5 6.0 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_30 PF13604.6 KKK21352.1 - 0.098 12.4 0.2 19 4.9 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA_25 PF13481.6 KKK21352.1 - 0.11 12.1 0.1 6.8 6.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain MeaB PF03308.16 KKK21352.1 - 0.13 11.2 0.0 0.27 10.2 0.0 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB CbiA PF01656.23 KKK21352.1 - 0.15 12.1 1.0 8.4 6.5 0.0 2.5 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_10 PF12846.7 KKK21352.1 - 0.17 10.8 0.3 1.5 7.7 0.0 2.3 2 0 0 2 2 2 0 AAA-like domain PhoH PF02562.16 KKK21352.1 - 0.2 11.1 0.1 22 4.4 0.0 2.5 2 0 0 2 2 2 0 PhoH-like protein Mt_ATP-synt_D PF05873.12 KKK21352.1 - 0.2 11.5 0.7 0.45 10.4 0.0 1.8 2 0 0 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) TrwB_AAD_bind PF10412.9 KKK21352.1 - 0.21 10.5 1.2 0.79 8.6 0.1 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_21 PF13304.6 KKK21352.1 - 0.45 10.3 4.5 21 4.8 0.0 3.6 4 0 0 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system ADH_N PF08240.12 KKK21353.1 - 8.7e-16 57.8 0.6 1.5e-15 57.0 0.6 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KKK21353.1 - 3e-13 49.9 0.2 2.8e-12 46.7 0.2 2.1 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KKK21353.1 - 1.1e-06 29.8 0.0 2e-06 28.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KKK21353.1 - 1.1e-05 25.0 0.0 0.019 14.4 0.0 2.3 2 0 0 2 2 2 2 Glucose dehydrogenase C-terminus UDPG_MGDP_dh_N PF03721.14 KKK21353.1 - 0.0033 17.0 0.0 0.0055 16.3 0.0 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.19 KKK21353.1 - 0.0045 16.4 0.0 0.0076 15.6 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_25 PF13649.6 KKK21353.1 - 0.025 15.3 0.0 0.049 14.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 KKK21353.1 - 0.042 13.4 0.0 0.074 12.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_2 PF00891.18 KKK21353.1 - 0.14 11.4 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain HpcH_HpaI PF03328.14 KKK21354.1 - 2.1e-33 115.4 0.0 2.4e-33 115.1 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PK PF00224.21 KKK21354.1 - 0.032 13.1 1.1 1.2 7.9 0.1 1.9 1 1 1 2 2 2 0 Pyruvate kinase, barrel domain Glyco_hydro_11 PF00457.17 KKK21355.1 - 1.5e-78 262.5 17.6 1.5e-78 262.5 17.6 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 11 CBM_1 PF00734.18 KKK21355.1 - 1.2e-11 44.3 12.9 1.2e-11 44.3 12.9 2.3 2 0 0 2 2 2 1 Fungal cellulose binding domain SOG2 PF10428.9 KKK21355.1 - 0.31 10.2 9.5 0.41 9.8 9.5 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Methyltransf_2 PF00891.18 KKK21356.1 - 6.4e-17 61.5 0.0 1.1e-16 60.8 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_25 PF13649.6 KKK21356.1 - 0.0012 19.6 0.0 0.0026 18.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KKK21356.1 - 0.019 14.8 0.0 0.037 13.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 KKK21356.1 - 0.048 14.4 0.0 0.2 12.4 0.0 2.1 3 0 0 3 3 3 0 Methyltransferase domain MFS_1 PF07690.16 KKK21357.1 - 1.2e-37 129.7 24.5 1.2e-37 129.7 24.5 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KKK21357.1 - 1.2e-14 54.1 6.0 1.2e-14 54.1 6.0 1.7 2 1 1 3 3 3 1 Sugar (and other) transporter OATP PF03137.20 KKK21357.1 - 0.53 8.5 11.4 0.24 9.6 5.1 2.6 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family ADH_zinc_N PF00107.26 KKK21358.1 - 1.5e-10 41.1 0.2 2.5e-10 40.4 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KKK21358.1 - 2.7e-07 30.5 0.0 1.1e-06 28.5 0.0 1.9 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain RmlD_sub_bind PF04321.17 KKK21358.1 - 0.0091 15.1 0.2 0.014 14.5 0.2 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain DUF2888 PF11135.8 KKK21358.1 - 0.033 14.2 0.0 0.053 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2888) CutC PF03932.14 KKK21358.1 - 0.19 11.2 0.1 0.35 10.3 0.1 1.3 1 0 0 1 1 1 0 CutC family FAD_binding_4 PF01565.23 KKK21359.1 - 1.4e-24 86.5 3.4 2.2e-24 85.8 3.4 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KKK21359.1 - 5.9e-15 55.1 0.1 1.1e-14 54.3 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like PLRV_ORF5 PF01690.17 KKK21359.1 - 0.2 10.3 0.0 0.28 9.8 0.0 1.2 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Glycos_transf_1 PF00534.20 KKK21360.1 - 2e-08 34.0 0.0 5e-08 32.7 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KKK21360.1 - 0.0019 18.6 0.0 0.0041 17.5 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Pkinase PF00069.25 KKK21399.1 - 1.3e-06 28.0 0.0 1.6e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KKK21399.1 - 0.00039 19.8 0.2 0.00061 19.2 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KKK21399.1 - 0.035 14.0 0.8 0.32 10.9 0.3 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KKK21399.1 - 0.058 12.2 0.0 0.083 11.7 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase EcKinase PF02958.20 KKK21399.1 - 0.083 12.2 0.2 1.3 8.2 0.1 2.0 1 1 0 2 2 2 0 Ecdysteroid kinase Pkinase PF00069.25 KKK21401.1 - 5.3e-15 55.5 0.0 8.5e-15 54.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK21401.1 - 0.00023 20.5 0.0 0.00064 19.1 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase DAO PF01266.24 KKK21402.1 - 6.3e-35 121.4 0.1 9.2e-35 120.9 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KKK21402.1 - 0.0065 15.8 0.0 0.1 11.8 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KKK21402.1 - 0.027 13.7 0.0 0.051 12.8 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Antimicrobial12 PF08107.11 KKK21402.1 - 0.047 13.5 0.5 0.14 12.0 0.5 1.8 1 0 0 1 1 1 0 Pleurocidin family HhH-GPD PF00730.25 KKK21414.1 - 5.8e-09 36.4 0.0 1.2e-08 35.4 0.0 1.5 1 1 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein Ecm33 PF12454.8 KKK21415.1 - 1.1e-13 51.0 0.9 1.1e-13 51.0 0.9 2.0 2 0 0 2 2 2 1 GPI-anchored cell wall organization protein LRR_5 PF13306.6 KKK21415.1 - 3e-07 30.4 0.3 0.011 15.7 0.2 2.6 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) FAM199X PF15814.5 KKK21415.1 - 0.0034 16.5 0.7 0.007 15.5 0.7 1.4 1 0 0 1 1 1 1 Protein family FAM199X IMUP PF15761.5 KKK21415.1 - 0.47 11.2 4.2 0.84 10.3 4.2 1.3 1 0 0 1 1 1 0 Immortalisation up-regulated protein Peptidase_A21 PF03566.13 KKK21415.1 - 3.6 5.7 10.9 0.25 9.5 4.1 1.9 2 0 0 2 2 2 0 Peptidase family A21 DEC-1_C PF04626.13 KKK21458.1 - 0.035 14.5 0.4 0.12 12.8 0.4 1.9 1 0 0 1 1 1 0 Dec-1 protein, C terminal region Carbpep_Y_N PF05388.11 KKK21458.1 - 3.4 8.2 5.3 0.56 10.7 0.7 2.0 2 0 0 2 2 2 0 Carboxypeptidase Y pro-peptide G-patch PF01585.23 KKK21474.1 - 1.7e-05 24.6 0.0 0.00024 20.9 0.0 2.5 1 1 0 1 1 1 1 G-patch domain DUF936 PF06075.12 KKK21474.1 - 0.083 11.8 28.6 0.097 11.6 28.6 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) SRP-alpha_N PF04086.13 KKK21474.1 - 0.34 10.8 34.8 0.45 10.4 34.8 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Pox_L3_FP4 PF03339.14 KKK21474.1 - 0.69 8.9 5.9 1.1 8.2 5.9 1.2 1 0 0 1 1 1 0 Poxvirus L3/FP4 protein G-patch_2 PF12656.7 KKK21474.1 - 2 8.5 0.0 2 8.5 0.0 3.5 2 1 0 2 2 2 0 G-patch domain SOBP PF15279.6 KKK21474.1 - 7 7.2 15.9 12 6.4 15.9 1.4 1 0 0 1 1 1 0 Sine oculis-binding protein Syja_N PF02383.18 KKK21475.1 - 2.2e-72 244.1 0.0 2.9e-72 243.7 0.0 1.1 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.23 KKK21475.1 - 8.5e-10 38.5 0.2 1.6e-09 37.6 0.2 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Herpes_ICP4_N PF03584.15 KKK21475.1 - 0.13 12.1 0.0 0.25 11.1 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus ICP4-like protein N-terminal region Kinesin PF00225.23 KKK21476.1 - 1.4e-97 326.7 0.0 3.3e-97 325.4 0.0 1.7 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KKK21476.1 - 2.2e-22 79.6 0.0 5.6e-22 78.3 0.0 1.7 1 0 0 1 1 1 1 Microtubule binding Lebercilin PF15619.6 KKK21476.1 - 0.0049 16.6 2.2 0.0049 16.6 2.2 2.4 2 0 0 2 2 2 1 Ciliary protein causing Leber congenital amaurosis disease PKcGMP_CC PF16808.5 KKK21476.1 - 0.14 12.0 6.0 0.089 12.7 0.7 3.1 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF4407 PF14362.6 KKK21476.1 - 1.5 8.1 10.5 0.44 9.8 1.9 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DAGAT PF03982.13 KKK21477.1 - 1.1e-86 290.4 0.0 1.4e-86 290.1 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase IGR PF09597.10 KKK21478.1 - 1.7e-25 88.9 0.4 3.5e-25 87.8 0.4 1.6 1 0 0 1 1 1 1 IGR protein motif Chorion_2 PF03964.15 KKK21478.1 - 0.0071 17.2 3.9 0.011 16.5 3.9 1.4 1 0 0 1 1 1 1 Chorion family 2 Apt1 PF10351.9 KKK21478.1 - 0.054 12.3 0.6 0.061 12.2 0.6 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain SSP160 PF06933.11 KKK21478.1 - 6.5 4.8 11.2 9.8 4.2 11.2 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF515 PF04415.12 KKK21478.1 - 9.8 4.4 8.5 13 4.1 8.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Pkinase PF00069.25 KKK21479.1 - 2.5e-63 213.9 0.0 2.9e-63 213.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK21479.1 - 3.4e-33 115.0 0.0 5.4e-33 114.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KKK21479.1 - 0.098 12.0 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Pkinase PF00069.25 KKK21480.1 - 1.1e-67 228.1 0.0 6.8e-66 222.3 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK21480.1 - 3.8e-34 118.2 0.0 2.2e-28 99.3 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase FHA PF00498.26 KKK21480.1 - 3.1e-14 53.1 0.0 6.8e-14 52.0 0.0 1.6 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.6 KKK21480.1 - 1e-07 31.6 0.2 0.0057 16.0 0.0 3.1 3 0 0 3 3 3 2 Kinase-like Yop-YscD_cpl PF16697.5 KKK21480.1 - 4e-05 23.9 0.0 9.5e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain APH PF01636.23 KKK21480.1 - 0.0021 18.0 0.2 0.018 15.0 0.2 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KKK21480.1 - 0.0026 16.6 1.7 0.007 15.2 0.1 2.3 2 1 0 2 2 2 1 Fungal protein kinase RIO1 PF01163.22 KKK21480.1 - 0.014 15.0 0.1 0.042 13.5 0.0 1.7 2 0 0 2 2 2 0 RIO1 family Pox_ser-thr_kin PF05445.11 KKK21480.1 - 0.042 12.8 0.1 0.063 12.2 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kdo PF06293.14 KKK21480.1 - 0.047 13.0 0.0 0.087 12.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KKK21480.1 - 0.062 12.2 1.2 0.072 12.0 0.0 1.6 2 0 0 2 2 2 0 Haspin like kinase domain FTA2 PF13095.6 KKK21480.1 - 0.073 12.7 0.0 2.1 7.9 0.0 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 YrbL-PhoP_reg PF10707.9 KKK21480.1 - 0.15 11.6 0.0 0.27 10.7 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL p450 PF00067.22 KKK21481.1 - 9.8e-77 258.6 0.0 1.1e-76 258.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 PI3_PI4_kinase PF00454.27 KKK21482.1 - 3.5e-39 135.1 0.0 2e-36 126.1 0.0 3.2 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 KKK21482.1 - 4e-25 88.3 0.1 8.5e-25 87.2 0.1 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PIN_12 PF16289.5 KKK21483.1 - 1.3 9.5 7.8 2.2 8.7 7.8 1.3 1 0 0 1 1 1 0 PIN domain Asp-B-Hydro_N PF05279.11 KKK21483.1 - 3.7 7.5 21.4 7.8 6.5 21.4 1.4 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF4778 PF16008.5 KKK21483.1 - 7.2 6.6 13.2 39 4.2 9.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4778) DUF724 PF05266.14 KKK21483.1 - 8.7 6.1 16.3 14 5.5 16.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Hexapep PF00132.24 KKK21493.1 - 5.7e-05 22.7 2.7 0.0001 21.9 1.0 2.3 2 1 0 2 2 2 1 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 KKK21493.1 - 0.0014 19.0 0.0 0.0026 18.1 0.0 1.6 1 1 0 1 1 1 1 MobA-like NTP transferase domain Fucokinase PF07959.12 KKK21493.1 - 0.042 12.8 0.1 0.071 12.0 0.1 1.3 1 0 0 1 1 1 0 L-fucokinase GTP_EFTU PF00009.27 KKK21493.1 - 0.11 12.0 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain DUF4954 PF16314.5 KKK21493.1 - 0.16 10.0 0.2 0.24 9.5 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4954) NTP_transferase PF00483.23 KKK21493.1 - 0.17 11.4 0.0 0.28 10.7 0.0 1.3 1 0 0 1 1 1 0 Nucleotidyl transferase Hexapep_2 PF14602.6 KKK21493.1 - 0.89 9.4 2.8 1.3 8.8 1.4 2.1 2 1 0 2 2 2 0 Hexapeptide repeat of succinyl-transferase Shadoo PF14999.6 KKK21494.1 - 0.026 14.6 0.5 0.074 13.1 0.5 1.8 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective Spt20 PF12090.8 KKK21495.1 - 6e-63 212.6 1.5 6e-63 212.6 1.5 7.3 3 2 2 6 6 6 1 Spt20 family Pkinase PF00069.25 KKK21515.1 - 3.4e-31 108.6 0.0 5.1e-31 108.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK21515.1 - 3.3e-24 85.6 0.0 5.4e-24 84.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase NdhL PF10716.9 KKK21523.1 - 0.11 12.5 1.1 0.37 10.8 1.1 1.9 1 0 0 1 1 1 0 NADH dehydrogenase transmembrane subunit CorA PF01544.18 KKK21525.1 - 0.00014 21.3 0.6 0.00031 20.2 0.6 1.5 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein 7TM_GPCR_Sru PF10322.9 KKK21525.1 - 0.029 13.7 0.1 0.062 12.6 0.1 1.5 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Sru P53_TAD PF08563.11 KKK21525.1 - 0.1 12.1 0.2 0.19 11.2 0.2 1.5 1 0 0 1 1 1 0 P53 transactivation motif DUF5326 PF17260.2 KKK21525.1 - 2.3 8.4 4.5 5.3 7.3 4.5 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5326) Metallophos PF00149.28 KKK21526.1 - 1e-32 114.3 1.1 1.9e-32 113.5 1.1 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.6 KKK21526.1 - 3.6e-14 53.4 0.4 1.2e-13 51.7 0.1 2.1 2 0 0 2 2 2 1 Iron/zinc purple acid phosphatase-like protein C Pur_ac_phosph_N PF16656.5 KKK21526.1 - 1.4e-12 48.0 0.7 3.9e-12 46.6 0.3 2.0 2 0 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain PhoD_N PF16655.5 KKK21526.1 - 0.1 13.2 0.1 0.27 11.8 0.1 1.7 1 0 0 1 1 1 0 PhoD-like phosphatase, N-terminal domain Mannosyl_trans3 PF11051.8 KKK21527.1 - 4.6e-61 206.6 0.0 1.5e-60 204.9 0.0 1.8 1 1 0 1 1 1 1 Mannosyltransferase putative MAPEG PF01124.18 KKK21527.1 - 3.1e-20 72.4 0.2 5.5e-20 71.6 0.2 1.4 1 0 0 1 1 1 1 MAPEG family Sulfatase PF00884.23 KKK21528.1 - 5.9e-66 223.0 1.0 7.6e-66 222.6 1.0 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 KKK21528.1 - 0.0054 16.4 1.4 2.2 7.8 0.3 2.6 3 0 0 3 3 3 2 Type I phosphodiesterase / nucleotide pyrophosphatase DUF4976 PF16347.5 KKK21528.1 - 0.0066 16.7 0.1 0.014 15.6 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4976) DUF2235 PF09994.9 KKK21529.1 - 4.1e-71 239.7 0.0 9e-71 238.6 0.0 1.5 2 0 0 2 2 2 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Caps_synth PF05704.12 KKK21529.1 - 1.4e-07 31.2 0.0 3.2e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein Gly_transf_sug PF04488.15 KKK21529.1 - 0.0041 17.7 0.0 0.0093 16.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif DUF4044 PF13253.6 KKK21529.1 - 0.24 10.9 0.0 0.61 9.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) MFS_1 PF07690.16 KKK21530.1 - 9.3e-41 139.9 35.0 9.3e-41 139.9 35.0 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KKK21530.1 - 1.2e-09 37.6 10.1 1.2e-09 37.6 10.1 3.1 3 0 0 3 3 3 2 Sugar (and other) transporter MFS_4 PF06779.14 KKK21530.1 - 8.6e-06 25.3 5.2 8.6e-06 25.3 5.2 2.2 2 1 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB Aldo_ket_red PF00248.21 KKK21531.1 - 6.5e-56 189.7 0.0 7.4e-56 189.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family MDD_C PF18376.1 KKK21533.1 - 1.1e-64 217.6 0.0 1.5e-64 217.2 0.0 1.2 1 0 0 1 1 1 1 Mevalonate 5-diphosphate decarboxylase C-terminal domain GHMP_kinases_N PF00288.26 KKK21533.1 - 2.5e-09 37.2 0.6 8e-09 35.6 0.6 1.9 1 0 0 1 1 1 1 GHMP kinases N terminal domain Dicer_dimer PF03368.14 KKK21533.1 - 0.0025 17.9 0.1 0.0092 16.1 0.0 1.9 1 1 0 2 2 2 1 Dicer dimerisation domain Ndc1_Nup PF09531.10 KKK21534.1 - 1.7e-185 618.3 10.3 8.1e-129 431.1 6.1 2.0 1 1 1 2 2 2 2 Nucleoporin protein Ndc1-Nup zf-C2H2 PF00096.26 KKK21535.1 - 1.1 9.9 28.1 0.088 13.3 1.4 5.1 5 0 0 5 5 5 0 Zinc finger, C2H2 type zf-C2H2_2 PF12756.7 KKK21535.1 - 2.3 8.6 12.9 0.81 10.1 3.0 3.2 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 KKK21535.1 - 9.5 7.4 23.2 2.1 9.4 1.8 5.1 4 0 0 4 4 4 0 C2H2-type zinc finger Cyto_heme_lyase PF01265.17 KKK21536.1 - 8.6e-40 137.1 2.4 3.5e-35 122.0 0.0 3.3 1 1 2 3 3 3 3 Cytochrome c/c1 heme lyase Syntaxin_2 PF14523.6 KKK21537.1 - 1.3e-24 86.5 2.5 1.3e-24 86.5 2.5 2.6 2 1 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.19 KKK21537.1 - 2.1e-13 50.0 1.6 2.1e-13 50.0 1.6 2.0 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.25 KKK21537.1 - 7.6e-05 22.5 15.5 0.00017 21.3 15.5 1.6 1 1 0 1 1 1 1 Syntaxin Synaptobrevin PF00957.21 KKK21537.1 - 0.019 14.8 0.2 0.071 12.9 0.2 2.0 1 0 0 1 1 1 0 Synaptobrevin K_channel_TID PF07941.11 KKK21537.1 - 0.28 11.7 8.3 0.14 12.6 3.6 2.3 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain Nre_C PF04895.12 KKK21537.1 - 0.34 10.9 0.2 0.34 10.9 0.2 2.2 2 0 0 2 2 2 0 Archaeal Nre, C-terminal DUF883 PF05957.13 KKK21537.1 - 1.8 9.2 11.7 1.5 9.4 0.1 3.2 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) SUIM_assoc PF16619.5 KKK21537.1 - 1.8 8.7 9.1 3.9 7.6 9.1 1.6 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 zf-C2H2 PF00096.26 KKK21556.1 - 1.9e-17 62.6 39.6 3.2e-05 24.1 5.0 4.3 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KKK21556.1 - 3.8e-16 58.7 27.7 1.5e-05 25.2 2.1 4.6 4 1 0 4 4 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 KKK21556.1 - 4.1e-06 27.2 35.4 0.08 13.8 3.8 4.4 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_8 PF15909.5 KKK21556.1 - 0.037 14.3 12.1 0.65 10.3 0.5 3.0 1 1 1 2 2 2 0 C2H2-type zinc ribbon TFIIA PF03153.13 KKK21556.1 - 1.5 8.8 8.8 1.6 8.7 8.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit adh_short PF00106.25 KKK21557.1 - 1.9e-08 34.0 0.0 1.6e-05 24.5 0.0 3.2 1 1 0 1 1 1 1 short chain dehydrogenase Imm_superinfect PF14373.6 KKK21557.1 - 0.41 10.6 3.6 3.4 7.7 0.5 2.8 2 0 0 2 2 2 0 Superinfection immunity protein Aminotran_1_2 PF00155.21 KKK21558.1 - 1.5e-28 100.1 0.0 8.2e-28 97.6 0.0 1.9 1 1 0 1 1 1 1 Aminotransferase class I and II Suc_Fer-like PF06999.12 KKK21559.1 - 1.6e-67 227.1 0.0 2.2e-67 226.7 0.0 1.2 1 0 0 1 1 1 1 Sucrase/ferredoxin-like DUF4129 PF13559.6 KKK21559.1 - 3.8e-06 27.1 0.0 1.3e-05 25.3 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4129) NICE-3 PF07406.11 KKK21559.1 - 0.0081 16.2 0.1 0.016 15.2 0.1 1.5 1 0 0 1 1 1 1 NICE-3 protein PH_10 PF15411.6 KKK21560.1 - 5.5e-32 110.6 0.0 9.6e-32 109.8 0.0 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain PB1 PF00564.24 KKK21561.1 - 1.1e-10 41.3 0.1 1.2e-10 41.1 0.1 1.1 1 0 0 1 1 1 1 PB1 domain DUF5645 PF18713.1 KKK21561.1 - 0.064 13.5 0.1 0.072 13.4 0.1 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF5645) G_glu_transpept PF01019.21 KKK21571.1 - 1.8e-161 538.4 0.2 2.4e-161 538.0 0.2 1.2 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase TPP_enzyme_N PF02776.18 KKK21571.1 - 1.8e-36 125.4 0.0 3.8e-36 124.3 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain ADH_N PF08240.12 KKK21571.1 - 4.5e-28 97.3 7.2 1.1e-27 96.1 7.2 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KKK21571.1 - 1e-16 61.1 0.4 3.2e-16 59.5 0.4 1.9 1 0 0 1 1 1 1 Zinc-binding dehydrogenase TPP_enzyme_C PF02775.21 KKK21571.1 - 1.2e-16 60.9 0.1 3.5e-16 59.3 0.1 1.8 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 KKK21571.1 - 2.2e-16 59.8 0.0 4.9e-16 58.7 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain ADH_zinc_N_2 PF13602.6 KKK21571.1 - 0.00023 22.2 0.3 0.00085 20.4 0.3 2.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Git3 PF11710.8 KKK21572.1 - 2.4e-38 131.9 18.4 5.3e-38 130.8 18.4 1.5 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 GPR_Gpa2_C PF11970.8 KKK21572.1 - 1.2e-14 54.1 0.1 1.2e-14 54.1 0.1 2.2 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 C-term 7tm_1 PF00001.21 KKK21572.1 - 0.00023 20.6 11.9 0.00023 20.6 11.9 1.9 1 1 1 2 2 2 1 7 transmembrane receptor (rhodopsin family) Orf78 PF06024.12 KKK21572.1 - 7.1 7.0 5.8 3.8 7.9 0.1 3.0 3 0 0 3 3 3 0 Orf78 (ac78) HhH-GPD PF00730.25 KKK21573.1 - 6.9e-07 29.7 0.0 3.3e-06 27.5 0.0 2.1 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein IL6 PF00489.17 KKK21573.1 - 0.091 12.3 0.6 0.19 11.3 0.6 1.4 1 0 0 1 1 1 0 Interleukin-6/G-CSF/MGF family Ribosomal_L24e PF01246.20 KKK21592.1 - 1.8e-28 98.6 2.1 1.8e-28 98.6 2.1 2.1 2 0 0 2 2 2 1 Ribosomal protein L24e Fungal_trans PF04082.18 KKK21593.1 - 3.3e-26 91.9 0.0 1.7e-25 89.6 0.0 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK21593.1 - 8.1e-10 38.7 13.1 1.5e-09 37.8 13.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pam16 PF03656.13 KKK21594.1 - 2.6e-07 30.7 0.1 3.3e-07 30.4 0.1 1.4 1 1 0 1 1 1 1 Pam16 DnaJ PF00226.31 KKK21594.1 - 5e-05 23.3 0.1 8.6e-05 22.6 0.1 1.3 1 0 0 1 1 1 1 DnaJ domain AAA PF00004.29 KKK21595.1 - 3.6e-43 147.2 0.0 1.1e-42 145.6 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) FtsH_ext PF06480.15 KKK21595.1 - 1.8e-12 47.5 0.1 4.4e-12 46.3 0.1 1.7 1 0 0 1 1 1 1 FtsH Extracellular AAA_lid_3 PF17862.1 KKK21595.1 - 1.7e-06 27.7 0.2 5.1e-06 26.2 0.2 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 KKK21595.1 - 0.00012 22.1 0.0 0.0004 20.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KKK21595.1 - 0.0023 18.4 0.2 0.16 12.3 0.2 2.7 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KKK21595.1 - 0.0023 18.2 0.0 0.78 10.0 0.1 3.1 3 0 0 3 3 3 1 AAA domain TIP49 PF06068.13 KKK21595.1 - 0.0072 15.6 0.1 0.012 14.8 0.1 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain RuvB_N PF05496.12 KKK21595.1 - 0.0074 16.0 0.0 0.022 14.5 0.0 1.8 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Serinc PF03348.15 KKK21595.1 - 0.011 14.7 0.1 0.016 14.2 0.1 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) AAA_2 PF07724.14 KKK21595.1 - 0.033 14.3 0.0 0.12 12.5 0.0 1.9 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_17 PF13207.6 KKK21595.1 - 0.062 13.7 0.2 0.27 11.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 KKK21595.1 - 0.086 12.6 0.1 0.21 11.3 0.1 1.6 1 1 0 1 1 1 0 IstB-like ATP binding protein DUF935 PF06074.12 KKK21595.1 - 0.1 11.4 1.8 0.096 11.4 0.2 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF935) AAA_11 PF13086.6 KKK21595.1 - 0.11 12.3 4.7 4 7.2 1.0 2.2 2 0 0 2 2 2 0 AAA domain UBN_AB PF14075.6 KKK21595.1 - 4 7.1 5.6 10 5.8 5.6 1.6 1 1 0 1 1 1 0 Ubinuclein conserved middle domain GTP_EFTU PF00009.27 KKK21602.1 - 1.2e-41 142.4 0.0 2.1e-41 141.6 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 KKK21602.1 - 9e-27 93.6 0.7 1.6e-26 92.8 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 KKK21602.1 - 2.3e-07 31.1 0.5 5.9e-07 29.8 0.5 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KKK21602.1 - 0.021 14.9 0.0 0.093 12.8 0.0 2.1 1 1 0 1 1 1 0 50S ribosome-binding GTPase Mitofilin PF09731.9 KKK21602.1 - 0.14 11.0 12.5 0.2 10.5 12.5 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein CytochromB561_N PF09786.9 KKK21602.1 - 0.26 10.2 6.9 0.39 9.6 6.9 1.2 1 0 0 1 1 1 0 Cytochrome B561, N terminal Hamartin PF04388.12 KKK21602.1 - 0.27 9.9 7.7 0.37 9.4 7.7 1.1 1 0 0 1 1 1 0 Hamartin protein TFIIA PF03153.13 KKK21602.1 - 0.42 10.6 25.0 0.7 9.8 25.0 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit WGG PF10273.9 KKK21603.1 - 6e-29 100.5 0.3 9.6e-29 99.9 0.3 1.3 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 NOA36 PF06524.12 KKK21603.1 - 0.32 10.3 4.4 0.46 9.8 4.4 1.2 1 0 0 1 1 1 0 NOA36 protein RRP7 PF12923.7 KKK21603.1 - 2.2 8.5 6.7 15 5.7 6.7 2.1 1 1 0 1 1 1 0 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain DNA_pol_phi PF04931.13 KKK21603.1 - 2.2 6.3 8.6 3.1 5.8 8.6 1.2 1 0 0 1 1 1 0 DNA polymerase phi Med13_C PF06333.12 KKK21604.1 - 1.6e-91 307.0 0.5 1.6e-91 307.0 0.5 1.9 2 0 0 2 2 2 1 Mediator complex subunit 13 C-terminal domain Med13_N PF11597.8 KKK21604.1 - 9.6e-72 242.0 0.6 1.5e-71 241.4 0.6 1.3 1 0 0 1 1 1 1 Mediator complex subunit 13 N-terminal MID_MedPIWI PF18296.1 KKK21604.1 - 4.3e-35 121.7 0.5 1.1e-19 71.2 0.4 2.6 1 1 1 2 2 2 2 MID domain of medPIWI Ran-binding PF05508.11 KKK21605.1 - 3.7e-124 413.8 0.8 4.9e-124 413.4 0.8 1.1 1 0 0 1 1 1 1 RanGTP-binding protein ATG13 PF10033.9 KKK21606.1 - 1.3e-72 244.4 0.0 1.8e-72 243.9 0.0 1.2 1 0 0 1 1 1 1 Autophagy-related protein 13 NUC153 PF08159.12 KKK21608.1 - 4.8e-12 45.5 0.5 1.2e-11 44.2 0.5 1.7 1 0 0 1 1 1 1 NUC153 domain WD40 PF00400.32 KKK21608.1 - 1.4e-05 25.7 0.0 0.7 10.9 0.0 4.9 5 0 0 5 5 5 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKK21608.1 - 0.021 15.1 0.0 0.092 13.1 0.0 2.1 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain SAPS PF04499.15 KKK21608.1 - 3.6 6.2 6.7 5.3 5.7 6.7 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein GREB1 PF15782.5 KKK21608.1 - 6.1 3.8 7.7 8.4 3.4 7.7 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer RCC1 PF00415.18 KKK21609.1 - 2.1e-22 79.5 0.4 6.9e-05 23.4 0.0 6.2 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.31 KKK21609.1 - 5.1e-15 55.7 0.3 4.4e-09 36.5 0.0 2.8 2 0 0 2 2 2 2 BTB/POZ domain RCC1_2 PF13540.6 KKK21609.1 - 5.5e-13 48.3 6.3 3.8e-09 36.1 0.2 4.2 4 0 0 4 4 4 2 Regulator of chromosome condensation (RCC1) repeat Ank_4 PF13637.6 KKK21609.1 - 4.7e-06 27.0 0.2 6.1e-05 23.5 0.1 2.5 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KKK21609.1 - 3.7e-05 23.8 0.1 0.48 11.2 0.0 3.3 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 KKK21609.1 - 0.0026 18.3 0.0 0.0058 17.2 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KKK21609.1 - 0.1 13.0 0.2 1.4 9.3 0.0 2.8 3 0 0 3 3 3 0 Ankyrin repeats (many copies) VHS PF00790.19 KKK21610.1 - 1.2e-40 138.6 0.7 1.5e-39 135.1 0.0 2.2 2 0 0 2 2 2 1 VHS domain FYVE PF01363.21 KKK21610.1 - 5e-16 58.6 1.3 7.9e-16 58.0 1.3 1.3 1 0 0 1 1 1 1 FYVE zinc finger UIM PF02809.20 KKK21610.1 - 1.6e-05 24.5 13.2 0.0047 16.7 2.7 2.7 2 0 0 2 2 2 2 Ubiquitin interaction motif GAT PF03127.14 KKK21610.1 - 2.3e-05 24.6 0.0 0.00012 22.3 0.0 2.2 2 0 0 2 2 2 1 GAT domain FYVE_2 PF02318.16 KKK21610.1 - 0.071 13.3 0.4 0.14 12.3 0.4 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger Npa1 PF11707.8 KKK21610.1 - 0.072 12.4 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Ribosome 60S biogenesis N-terminal DZR PF12773.7 KKK21610.1 - 0.26 11.3 2.3 0.52 10.4 2.3 1.4 1 0 0 1 1 1 0 Double zinc ribbon OrfB_Zn_ribbon PF07282.11 KKK21610.1 - 0.69 9.9 2.8 2.9 7.9 3.1 1.8 2 0 0 2 2 2 0 Putative transposase DNA-binding domain UCH PF00443.29 KKK21611.1 - 4.6e-50 170.5 0.0 6.9e-50 169.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KKK21611.1 - 2.9e-16 60.0 1.4 1e-13 51.6 0.1 2.4 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Rhodanese PF00581.20 KKK21611.1 - 4e-05 24.1 0.0 0.0001 22.8 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain BSD PF03909.17 KKK21612.1 - 1.1e-19 70.2 1.2 2.1e-19 69.3 1.2 1.5 1 0 0 1 1 1 1 BSD domain Suf PF05843.14 KKK21612.1 - 0.094 12.7 3.0 0.19 11.7 3.0 1.5 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) KH_1 PF00013.29 KKK21613.1 - 1.2e-93 307.0 22.3 1.3e-11 44.2 0.1 13.6 13 1 0 13 13 13 9 KH domain KH_2 PF07650.17 KKK21613.1 - 8.3e-11 41.6 26.8 0.0054 16.5 0.3 7.8 6 2 2 8 8 8 5 KH domain SLS PF14611.6 KKK21613.1 - 3.2e-10 40.2 4.1 0.082 12.7 0.1 8.1 4 3 4 9 9 9 2 Mitochondrial inner-membrane-bound regulator KH_4 PF13083.6 KKK21613.1 - 0.0054 16.6 7.1 26 4.8 0.0 5.9 6 0 0 6 6 6 0 KH domain RL10P_insert PF17777.1 KKK21613.1 - 0.016 15.2 0.1 0.066 13.2 0.1 2.0 1 0 0 1 1 1 0 Insertion domain in 60S ribosomal protein L10P KH_5 PF13184.6 KKK21613.1 - 0.27 11.4 6.6 49 4.1 0.2 5.8 6 0 0 6 6 6 0 NusA-like KH domain YbbR PF07949.12 KKK21613.1 - 4.1 7.8 7.3 8.9 6.7 0.1 4.9 6 0 0 6 6 6 0 YbbR-like protein Cyt-b5 PF00173.28 KKK21614.1 - 1.5e-22 79.5 0.1 2e-22 79.1 0.1 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain YqzH PF14164.6 KKK21614.1 - 0.11 12.6 0.1 0.18 11.9 0.1 1.4 1 0 0 1 1 1 0 YqzH-like protein Pkinase PF00069.25 KKK21615.1 - 6.9e-72 242.0 0.0 1.2e-71 241.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK21615.1 - 6.2e-45 153.5 0.0 9.9e-45 152.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 KKK21615.1 - 7.8e-15 55.0 0.4 2.3e-14 53.5 0.4 1.8 1 0 0 1 1 1 1 P21-Rho-binding domain Pkinase_fungal PF17667.1 KKK21615.1 - 7.1e-07 28.3 0.7 1.7e-06 27.1 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 KKK21615.1 - 1.5e-06 27.7 0.0 2.5e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KKK21615.1 - 0.053 12.9 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KKK21615.1 - 0.17 10.8 0.3 0.45 9.4 0.3 1.6 1 1 0 1 1 1 0 Haspin like kinase domain DSHCT PF08148.12 KKK21615.1 - 0.17 11.5 0.0 0.4 10.3 0.0 1.5 1 0 0 1 1 1 0 DSHCT (NUC185) domain FTA2 PF13095.6 KKK21615.1 - 0.29 10.7 2.8 0.36 10.4 0.0 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 KKK21615.1 - 2.6 7.9 10.4 0.38 10.6 0.2 3.0 2 1 1 3 3 3 0 Phosphotransferase enzyme family DUF3040 PF11239.8 KKK21617.1 - 0.018 15.3 0.1 0.04 14.2 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3040) Serinc PF03348.15 KKK21617.1 - 0.097 11.6 1.7 0.11 11.3 1.7 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) LAX PF15681.5 KKK21617.1 - 0.14 11.0 0.7 0.17 10.7 0.7 1.1 1 0 0 1 1 1 0 Lymphocyte activation family X DUF872 PF05915.12 KKK21617.1 - 0.17 12.0 0.1 0.19 11.9 0.1 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF872) Sarcoglycan_1 PF04790.13 KKK21617.1 - 0.4 10.0 2.8 0.52 9.6 2.8 1.1 1 0 0 1 1 1 0 Sarcoglycan complex subunit protein TMEM190 PF15431.6 KKK21617.1 - 0.86 9.8 3.8 1 9.5 3.6 1.3 1 1 0 1 1 1 0 Transmembrane protein 190 DUF4381 PF14316.6 KKK21617.1 - 2.3 8.4 7.6 1.2 9.3 5.7 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4381) Amidase PF01425.21 KKK21618.1 - 3.3e-81 273.6 0.0 5.5e-81 272.8 0.0 1.3 1 1 0 1 1 1 1 Amidase HMGL-like PF00682.19 KKK21619.1 - 3.5e-41 141.5 0.0 4.1e-41 141.3 0.0 1.1 1 0 0 1 1 1 1 HMGL-like SLAC1 PF03595.17 KKK21621.1 - 7.3e-98 327.8 54.7 8.2e-98 327.6 54.7 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel AT_hook PF02178.19 KKK21622.1 - 0.0087 15.8 37.7 0.06 13.2 2.0 4.7 4 0 0 4 4 4 3 AT hook motif Ank_2 PF12796.7 KKK21624.1 - 3.7e-39 133.2 1.0 8.7e-13 48.7 0.1 3.5 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) DHHC PF01529.20 KKK21624.1 - 1.3e-33 115.9 11.7 1.3e-33 115.9 11.7 2.7 2 1 0 2 2 2 1 DHHC palmitoyltransferase Ank_5 PF13857.6 KKK21624.1 - 1.9e-27 95.0 3.2 4.7e-09 36.3 0.0 4.7 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KKK21624.1 - 4.8e-23 78.7 4.4 6e-08 32.4 0.1 5.9 5 0 0 5 5 5 4 Ankyrin repeat Ank PF00023.30 KKK21624.1 - 7.7e-23 79.9 1.7 2.4e-06 27.7 0.0 5.3 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.6 KKK21624.1 - 3.7e-22 78.4 12.5 4.7e-07 30.2 0.4 4.8 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Cyclin PF08613.11 KKK21625.1 - 3.1e-36 125.2 0.0 3.9e-36 124.8 0.0 1.1 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 KKK21625.1 - 0.0051 16.6 0.1 0.0085 15.8 0.1 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain ABC_tran PF00005.27 KKK21636.1 - 5.4e-47 159.8 0.0 7e-30 104.3 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KKK21636.1 - 1.4e-36 126.6 37.1 1e-24 87.7 15.1 3.4 4 1 1 5 5 5 2 ABC transporter transmembrane region SMC_N PF02463.19 KKK21636.1 - 6.6e-12 45.3 0.1 0.0011 18.4 0.0 4.3 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KKK21636.1 - 1.2e-05 25.9 0.1 0.019 15.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 KKK21636.1 - 3.5e-05 24.1 0.1 0.2 12.0 0.0 3.2 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KKK21636.1 - 0.00031 20.4 0.4 0.36 10.6 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 KKK21636.1 - 0.00072 20.0 1.1 0.2 12.0 0.1 3.0 2 0 0 2 2 2 1 AAA ATPase domain MMR_HSR1 PF01926.23 KKK21636.1 - 0.0012 18.9 0.0 0.083 13.0 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase T2SSE PF00437.20 KKK21636.1 - 0.0012 18.0 0.0 0.3 10.1 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein RsgA_GTPase PF03193.16 KKK21636.1 - 0.0054 16.6 0.0 2.8 7.8 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase IstB_IS21 PF01695.17 KKK21636.1 - 0.0086 15.8 0.0 0.13 12.0 0.0 2.6 2 0 0 2 2 2 1 IstB-like ATP binding protein DUF87 PF01935.17 KKK21636.1 - 0.013 15.6 2.1 0.37 10.9 0.1 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain DUF2075 PF09848.9 KKK21636.1 - 0.013 14.7 0.0 0.7 9.1 0.0 2.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_25 PF13481.6 KKK21636.1 - 0.02 14.5 0.0 3 7.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 KKK21636.1 - 0.12 11.6 0.2 22 4.1 0.0 2.9 3 0 0 3 3 3 0 NB-ARC domain Zeta_toxin PF06414.12 KKK21636.1 - 0.13 11.5 0.1 14 4.9 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin MeaB PF03308.16 KKK21636.1 - 0.17 10.8 0.0 0.35 9.8 0.0 1.5 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB GFA PF04828.14 KKK21637.1 - 1e-22 80.3 0.2 1.4e-22 79.8 0.2 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme PTR2 PF00854.21 KKK21638.1 - 2.1e-93 313.3 5.1 2.1e-93 313.3 5.1 1.8 2 1 0 2 2 2 1 POT family p450 PF00067.22 KKK21640.1 - 4.8e-42 144.3 0.0 8.4e-42 143.5 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 IF4E PF01652.18 KKK21641.1 - 1.9e-52 177.3 0.0 2.3e-52 177.0 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E RIIa PF02197.17 KKK21641.1 - 0.08 12.6 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Regulatory subunit of type II PKA R-subunit Mpv17_PMP22 PF04117.12 KKK21642.1 - 3.2e-23 81.7 1.0 5.8e-23 80.9 1.0 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family Ribosomal_S5 PF00333.20 KKK21643.1 - 1.2e-26 92.5 1.9 2.6e-26 91.4 1.0 2.0 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 KKK21643.1 - 1.2e-22 79.1 0.0 2.1e-22 78.4 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Phage_tail_NK PF16532.5 KKK21643.1 - 0.068 12.8 0.1 0.1 12.2 0.1 1.2 1 0 0 1 1 1 0 Sf6-type phage tail needle knob or tip of some Caudovirales FoP_duplication PF13865.6 KKK21643.1 - 10 6.8 16.9 1.1 9.8 12.7 1.6 2 0 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 DUF2039 PF10217.9 KKK21645.1 - 2.1 8.7 5.1 4.2 7.8 5.1 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) Beta_helix PF13229.6 KKK21646.1 - 0.11 12.3 12.6 0.071 13.0 2.6 3.0 1 1 0 2 2 2 0 Right handed beta helix region GGACT PF06094.12 KKK21648.1 - 1.7e-09 38.3 0.0 2.8e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like Ribosomal_S25 PF03297.15 KKK21649.1 - 2.6e-28 98.2 1.0 4.9e-28 97.3 1.0 1.4 1 0 0 1 1 1 1 S25 ribosomal protein ANAPC4_WD40 PF12894.7 KKK21649.1 - 0.00055 20.2 0.3 4.5 7.6 0.0 3.8 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KKK21649.1 - 0.0091 16.8 2.8 8.2 7.5 0.2 4.6 3 1 1 4 4 4 1 WD domain, G-beta repeat MarR_2 PF12802.7 KKK21649.1 - 0.15 11.9 0.1 0.29 11.1 0.1 1.4 1 0 0 1 1 1 0 MarR family PD40 PF07676.12 KKK21649.1 - 0.28 11.2 2.1 0.79 9.7 0.1 2.8 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Cyt-b5 PF00173.28 KKK21650.1 - 2.6e-10 40.3 0.0 3.8e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Gtr1_RagA PF04670.12 KKK21651.1 - 5.3e-69 232.1 0.2 9e-69 231.3 0.1 1.4 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region Arf PF00025.21 KKK21651.1 - 0.00017 21.1 0.0 0.00038 20.0 0.0 1.5 1 1 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KKK21651.1 - 0.0083 16.3 0.0 0.017 15.3 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 KKK21651.1 - 0.015 15.4 0.0 0.044 13.9 0.0 1.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase SRPRB PF09439.10 KKK21651.1 - 0.044 13.2 0.0 0.086 12.3 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 KKK21651.1 - 0.083 13.3 0.0 0.16 12.4 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_14 PF13173.6 KKK21651.1 - 0.14 12.2 0.0 0.39 10.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain Lactamase_B_4 PF13691.6 KKK21652.1 - 1.3e-24 85.7 0.1 5e-24 83.8 0.1 2.1 2 0 0 2 2 2 1 tRNase Z endonuclease Lactamase_B_2 PF12706.7 KKK21652.1 - 6.6e-10 38.8 0.0 4.1e-05 23.2 0.0 2.7 3 0 0 3 3 3 2 Beta-lactamase superfamily domain bZIP_1 PF00170.21 KKK21652.1 - 2.2e-08 34.1 10.0 5.4e-08 32.8 10.0 1.7 1 0 0 1 1 1 1 bZIP transcription factor Lactamase_B PF00753.27 KKK21652.1 - 0.00012 22.1 0.0 0.00041 20.4 0.0 1.9 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily bZIP_2 PF07716.15 KKK21652.1 - 0.00074 19.5 10.1 0.00074 19.5 10.1 2.8 3 0 0 3 3 3 1 Basic region leucine zipper His_Phos_2 PF00328.22 KKK21653.1 - 6.6e-13 48.8 0.0 3.4e-12 46.4 0.0 2.0 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) ABC_tran PF00005.27 KKK21654.1 - 3.3e-40 137.8 9.0 6e-21 75.4 0.1 3.7 3 1 0 3 3 2 2 ABC transporter AAA_21 PF13304.6 KKK21654.1 - 1.4e-09 38.2 9.6 0.00089 19.1 1.2 4.4 3 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran_Xtn PF12848.7 KKK21654.1 - 2e-09 37.4 2.6 2e-09 37.4 2.6 2.4 2 1 0 2 2 1 1 ABC transporter SMC_N PF02463.19 KKK21654.1 - 3.2e-09 36.6 5.5 0.015 14.8 0.0 4.3 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KKK21654.1 - 2.8e-06 27.0 0.7 0.0035 17.0 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 KKK21654.1 - 5.2e-06 27.1 10.2 0.0077 16.7 9.6 3.1 2 1 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 KKK21654.1 - 4.5e-05 23.5 0.2 0.11 12.5 0.0 3.2 2 0 0 2 2 2 2 50S ribosome-binding GTPase MeaB PF03308.16 KKK21654.1 - 0.00044 19.3 0.4 0.19 10.7 0.0 2.4 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_28 PF13521.6 KKK21654.1 - 0.00062 20.0 0.0 0.22 11.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 KKK21654.1 - 0.00087 19.7 0.0 1.2 9.6 0.0 3.2 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 KKK21654.1 - 0.00091 19.8 1.1 1.4 9.5 0.4 2.9 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KKK21654.1 - 0.0012 19.3 0.5 1.8 8.9 0.0 2.9 2 1 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 KKK21654.1 - 0.0014 18.5 0.1 2.5 8.0 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_5 PF07728.14 KKK21654.1 - 0.0018 18.3 0.9 0.39 10.7 0.0 3.4 3 1 0 3 3 3 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 KKK21654.1 - 0.0033 17.8 0.1 1.1 9.7 0.0 2.5 2 0 0 2 2 2 1 RNA helicase AAA_30 PF13604.6 KKK21654.1 - 0.0039 16.9 0.3 3.5 7.3 0.0 3.1 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KKK21654.1 - 0.0059 16.9 5.9 0.15 12.3 0.1 4.0 3 2 0 3 3 3 1 AAA domain NTPase_1 PF03266.15 KKK21654.1 - 0.0059 16.5 0.9 19 5.2 0.0 3.7 4 0 0 4 4 3 0 NTPase AAA_33 PF13671.6 KKK21654.1 - 0.0068 16.6 3.2 1.9 8.6 0.0 3.7 5 0 0 5 5 3 1 AAA domain AAA_27 PF13514.6 KKK21654.1 - 0.0077 15.8 1.3 0.039 13.6 0.0 2.6 3 0 0 3 3 3 1 AAA domain AAA_14 PF13173.6 KKK21654.1 - 0.0097 15.9 0.1 4.7 7.3 0.0 3.4 4 0 0 4 4 3 1 AAA domain AAA_13 PF13166.6 KKK21654.1 - 0.01 14.5 9.8 0.023 13.4 1.5 2.6 3 0 0 3 3 3 0 AAA domain AAA_25 PF13481.6 KKK21654.1 - 0.012 15.1 0.7 3.3 7.3 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_7 PF12775.7 KKK21654.1 - 0.017 14.6 0.1 0.23 11.0 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region NACHT PF05729.12 KKK21654.1 - 0.027 14.4 0.4 1.5 8.7 0.0 2.5 2 0 0 2 2 2 0 NACHT domain Lipase_GDSL_3 PF14606.6 KKK21654.1 - 0.13 12.4 1.1 0.41 10.8 0.0 2.4 2 1 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family AAA_24 PF13479.6 KKK21654.1 - 0.36 10.5 2.3 5.4 6.7 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_15 PF13175.6 KKK21654.1 - 0.46 10.1 0.0 0.46 10.1 0.0 3.4 3 1 0 4 4 4 0 AAA ATPase domain SesA PF17107.5 KKK21654.1 - 0.58 10.3 4.1 0.94 9.7 1.0 2.3 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases DUF87 PF01935.17 KKK21654.1 - 2.6 8.1 6.6 3.5 7.7 0.0 3.2 3 0 0 3 3 3 0 Helicase HerA, central domain V-SNARE_C PF12352.8 KKK21654.1 - 6.1 7.2 6.2 34 4.8 0.4 3.2 2 1 1 3 3 3 0 Snare region anchored in the vesicle membrane C-terminus FA_hydroxylase PF04116.13 KKK21655.1 - 5.5e-24 85.0 15.4 5.5e-24 85.0 15.4 2.2 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Ferrochelatase PF00762.19 KKK21674.1 - 3.5e-99 331.9 0.0 4.1e-99 331.7 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase Ku PF02735.16 KKK21675.1 - 3.7e-42 144.4 0.0 6.5e-42 143.6 0.0 1.4 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 KKK21675.1 - 4e-36 124.8 0.0 5.5e-36 124.4 0.0 1.2 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.14 KKK21675.1 - 7e-28 97.2 2.3 1.8e-27 95.9 2.3 1.7 1 0 0 1 1 1 1 Ku70/Ku80 C-terminal arm VWA_2 PF13519.6 KKK21675.1 - 0.045 14.4 0.0 0.41 11.3 0.0 2.4 3 0 0 3 3 3 0 von Willebrand factor type A domain VWA PF00092.28 KKK21675.1 - 0.072 13.3 0.0 0.71 10.1 0.0 2.1 2 0 0 2 2 2 0 von Willebrand factor type A domain SE PF08491.10 KKK21676.1 - 3.9e-95 318.0 0.0 4.8e-95 317.7 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.19 KKK21676.1 - 4.4e-07 29.5 0.1 0.00045 19.6 0.6 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 KKK21676.1 - 3.9e-06 26.7 0.1 7.3e-05 22.5 0.3 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.22 KKK21676.1 - 0.00065 18.9 0.2 0.035 13.2 0.3 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_8 PF13450.6 KKK21676.1 - 0.0013 18.9 0.6 0.0029 17.8 0.6 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 KKK21676.1 - 0.0017 17.8 0.7 0.0024 17.3 0.7 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 KKK21676.1 - 0.0033 16.7 0.5 0.046 13.0 0.1 2.1 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.14 KKK21676.1 - 0.0039 16.5 0.1 0.0065 15.7 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KKK21676.1 - 0.011 16.3 0.3 0.023 15.2 0.3 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KKK21676.1 - 0.011 14.8 1.8 0.02 14.0 1.8 1.4 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 KKK21676.1 - 0.038 12.7 0.2 0.069 11.8 0.2 1.4 1 0 0 1 1 1 0 HI0933-like protein ApbA PF02558.16 KKK21676.1 - 0.063 12.9 0.3 0.11 12.1 0.3 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Lycopene_cycl PF05834.12 KKK21676.1 - 0.072 12.1 2.5 0.058 12.4 0.5 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein ThiF PF00899.21 KKK21676.1 - 0.096 12.0 0.2 0.17 11.2 0.2 1.3 1 0 0 1 1 1 0 ThiF family GMC_oxred_N PF00732.19 KKK21676.1 - 0.14 11.5 0.5 8.4 5.7 0.1 2.3 2 0 0 2 2 2 0 GMC oxidoreductase PPR PF01535.20 KKK21677.1 - 0.00025 21.1 1.3 3.5 8.1 0.0 5.3 6 0 0 6 6 6 1 PPR repeat PPR_2 PF13041.6 KKK21677.1 - 0.016 15.4 0.3 20 5.4 0.1 4.0 4 0 0 4 4 4 0 PPR repeat family RHSP PF07999.11 KKK21677.1 - 0.058 12.2 0.0 0.36 9.6 0.0 1.9 2 0 0 2 2 2 0 Retrotransposon hot spot protein RPN7 PF10602.9 KKK21677.1 - 0.096 12.4 0.1 0.22 11.2 0.1 1.6 1 0 0 1 1 1 0 26S proteasome subunit RPN7 PH_9 PF15410.6 KKK21678.1 - 2e-19 70.1 0.0 1.2e-18 67.5 0.0 2.1 2 0 0 2 2 2 1 Pleckstrin homology domain Sec7 PF01369.20 KKK21678.1 - 2.1e-10 40.6 0.1 1.9e-06 27.7 0.2 2.5 1 1 1 2 2 2 2 Sec7 domain Zn_clus PF00172.18 KKK21679.1 - 1.4e-08 34.7 12.8 2.8e-08 33.7 12.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldose_epim PF01263.20 KKK21680.1 - 2.7e-58 197.7 0.0 3e-58 197.5 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase Ras PF00071.22 KKK21681.1 - 2.8e-37 127.8 0.0 3.6e-36 124.2 0.0 2.0 1 1 0 1 1 1 1 Ras family Roc PF08477.13 KKK21681.1 - 2.9e-10 40.4 0.0 7.4e-10 39.1 0.0 1.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 KKK21681.1 - 0.0069 16.5 0.0 0.014 15.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 KKK21681.1 - 0.027 13.9 0.0 0.068 12.6 0.0 1.7 1 1 1 2 2 2 0 ADP-ribosylation factor family NB-ARC PF00931.22 KKK21681.1 - 0.061 12.5 0.0 0.19 10.9 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain AAA_25 PF13481.6 KKK21681.1 - 0.17 11.5 0.1 1.7 8.2 0.0 2.5 2 1 1 3 3 3 0 AAA domain QRPTase_C PF01729.19 KKK21682.1 - 6.4e-47 159.5 0.8 9.6e-25 87.3 0.0 2.1 1 1 1 2 2 2 2 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.16 KKK21682.1 - 6e-05 23.0 0.0 0.0003 20.8 0.0 2.2 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, N-terminal domain Cnn_1N PF07989.11 KKK21683.1 - 1.3e-23 82.9 11.0 1.3e-23 82.9 11.0 11.9 7 2 3 11 11 11 2 Centrosomin N-terminal motif 1 Mto2_bdg PF12808.7 KKK21683.1 - 1.9e-22 79.3 28.8 6.9e-19 67.9 11.9 11.0 11 2 2 13 13 13 2 Micro-tubular organiser Mto1 C-term Mto2-binding region MliC PF09864.9 KKK21683.1 - 0.15 12.0 0.0 0.6 10.1 0.0 2.0 2 0 0 2 2 2 0 Membrane-bound lysozyme-inhibitor of c-type lysozyme UNC-50 PF05216.13 KKK21684.1 - 1.8e-83 279.5 6.9 2.1e-83 279.2 6.9 1.0 1 0 0 1 1 1 1 UNC-50 family Aldo_ket_red PF00248.21 KKK21700.1 - 4.3e-68 229.6 0.0 5.5e-68 229.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Aconitase PF00330.20 KKK21701.1 - 1.2e-151 505.9 0.0 1.4e-151 505.6 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KKK21701.1 - 9.3e-41 139.2 0.0 1.9e-40 138.2 0.0 1.6 1 0 0 1 1 1 1 Aconitase C-terminal domain WD40 PF00400.32 KKK21702.1 - 2.9e-12 46.9 14.2 0.0029 18.4 1.4 4.9 4 0 0 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKK21702.1 - 0.00012 22.3 0.5 0.073 13.4 0.0 3.5 3 1 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KKK21702.1 - 0.0099 14.9 0.1 4.9 6.0 0.0 2.8 3 0 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KKK21702.1 - 0.088 11.4 2.6 1.7 7.2 0.1 2.2 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Rav1p_C PF12234.8 KKK21702.1 - 0.15 10.4 0.0 0.21 10.0 0.0 1.1 1 0 0 1 1 1 0 RAVE protein 1 C terminal Glycos_transf_4 PF00953.21 KKK21703.1 - 1.3e-31 109.8 13.7 1.3e-31 109.8 13.7 2.7 3 1 0 3 3 3 1 Glycosyl transferase family 4 DUF2107 PF09880.9 KKK21703.1 - 2.5 8.3 8.6 6.7 6.9 0.7 3.4 3 0 0 3 3 3 0 Predicted membrane protein (DUF2107) AA_permease PF00324.21 KKK21704.1 - 3.9e-59 200.5 37.2 3.1e-31 108.5 17.5 1.9 2 0 0 2 2 2 2 Amino acid permease AA_permease_2 PF13520.6 KKK21704.1 - 1.5e-21 76.7 31.9 2.9e-21 75.8 31.9 1.4 1 1 0 1 1 1 1 Amino acid permease MTHFR PF02219.17 KKK21706.1 - 6.9e-98 327.5 0.0 1.5e-55 188.5 0.0 2.1 1 1 1 2 2 2 2 Methylenetetrahydrofolate reductase MHC_I_3 PF16497.5 KKK21706.1 - 0.16 11.5 0.0 0.44 10.0 0.0 1.7 1 0 0 1 1 1 0 MHC-I family domain ATP-synt_F PF01990.17 KKK21707.1 - 2.3e-33 114.4 0.1 2.7e-33 114.2 0.1 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit DUF257 PF03192.13 KKK21707.1 - 0.028 14.2 0.0 0.037 13.8 0.0 1.1 1 0 0 1 1 1 0 Pyrococcus protein of unknown function, DUF257 PIN_8 PF18476.1 KKK21707.1 - 0.11 12.3 0.0 0.13 12.1 0.0 1.1 1 0 0 1 1 1 0 PIN like domain DUF2418 PF10332.9 KKK21708.1 - 4.3e-34 116.9 1.1 7.4e-34 116.2 0.1 1.9 3 0 0 3 3 3 1 Protein of unknown function (DUF2418) Pribosyltran PF00156.27 KKK21709.1 - 3.1e-14 52.8 0.4 4.4e-14 52.3 0.4 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Alpha-amylase PF00128.24 KKK21710.1 - 1.4e-17 64.3 2.2 2.4e-17 63.5 0.8 2.1 2 1 0 2 2 2 1 Alpha amylase, catalytic domain Glyco_transf_5 PF08323.11 KKK21710.1 - 2.5e-14 53.5 0.1 4.3e-14 52.8 0.1 1.3 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 KKK21710.1 - 6.4e-05 22.5 0.0 0.00014 21.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KKK21710.1 - 0.0016 18.5 0.0 0.0045 17.0 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase Family 4 HCMVantigenic_N PF12154.8 KKK21725.1 - 3 8.0 8.2 0.22 11.6 2.9 1.9 2 0 0 2 2 2 0 Glycoprotein B N-terminal antigenic domain of HCMV tRNA-synt_1b PF00579.25 KKK21726.1 - 1.8e-60 204.7 0.0 2.2e-60 204.5 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) RTC4 PF14474.6 KKK21726.1 - 0.023 14.8 0.0 0.079 13.1 0.0 1.9 2 0 0 2 2 2 0 RTC4-like domain Alpha-amylase PF00128.24 KKK21727.1 - 8.1e-117 390.5 0.1 1.2e-116 389.9 0.1 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Malt_amylase_C PF16657.5 KKK21727.1 - 0.00013 22.0 0.0 0.00025 21.1 0.0 1.5 1 0 0 1 1 1 1 Maltogenic Amylase, C-terminal domain hDGE_amylase PF14701.6 KKK21727.1 - 0.022 13.9 0.0 0.056 12.5 0.0 1.6 2 0 0 2 2 2 0 Glycogen debranching enzyme, glucanotransferase domain Glyco_hydro_114 PF03537.13 KKK21727.1 - 0.056 12.8 0.0 1.8 7.8 0.0 2.3 2 0 0 2 2 2 0 Glycoside-hydrolase family GH114 Glyco_hydro_72 PF03198.14 KKK21728.1 - 8.4e-100 334.1 0.0 1.5e-99 333.2 0.0 1.4 1 1 0 1 1 1 1 Glucanosyltransferase Glyco_hydro_2_C PF02836.17 KKK21728.1 - 0.00093 18.4 0.0 0.0015 17.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Cellulase PF00150.18 KKK21728.1 - 0.0061 16.0 0.0 0.064 12.7 0.0 2.2 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Pkinase PF00069.25 KKK21729.1 - 3.5e-11 43.0 0.0 1.7e-08 34.1 0.0 2.4 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KKK21729.1 - 2.8e-07 30.1 0.0 1.2e-06 28.0 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 KKK21729.1 - 0.0016 17.8 0.0 0.0026 17.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Sds3 PF08598.11 KKK21730.1 - 7.7e-48 163.4 0.0 3.6e-45 154.7 0.0 2.1 1 1 0 1 1 1 1 Sds3-like HAUS6_N PF14661.6 KKK21730.1 - 0.069 12.7 0.1 0.069 12.7 0.1 1.6 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus FAM184 PF15665.5 KKK21730.1 - 0.82 9.4 5.9 0.15 11.8 1.6 1.8 2 0 0 2 2 2 0 Family with sequence similarity 184, A and B Mo-nitro_C PF06967.11 KKK21731.1 - 0.06 13.3 0.1 0.81 9.7 0.1 2.4 2 0 0 2 2 2 0 Mo-dependent nitrogenase C-terminus Ribonuc_L-PSP PF01042.21 KKK21732.1 - 1.1e-11 44.8 0.0 1.3e-11 44.5 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP Abhydrolase_1 PF00561.20 KKK21736.1 - 9.9e-13 48.3 0.1 1e-11 45.0 0.1 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KKK21736.1 - 2e-08 33.8 0.0 1.7e-07 30.8 0.0 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 F-box-like PF12937.7 KKK21737.1 - 0.0091 15.9 1.5 0.0091 15.9 1.5 2.3 2 0 0 2 2 2 1 F-box-like F-box_4 PF15966.5 KKK21737.1 - 0.022 14.6 1.1 0.057 13.3 1.1 1.7 1 1 0 1 1 1 0 F-box F-box PF00646.33 KKK21737.1 - 0.035 14.0 1.4 0.035 14.0 1.4 2.3 2 0 0 2 2 2 0 F-box domain Cohesin_load PF10345.9 KKK21738.1 - 2.7e-185 617.3 8.5 3.1e-185 617.1 8.5 1.0 1 0 0 1 1 1 1 Cohesin loading factor TPR_MalT PF17874.1 KKK21738.1 - 0.0013 18.2 17.0 0.28 10.5 0.0 4.1 3 1 0 3 3 3 3 MalT-like TPR region TPR_12 PF13424.6 KKK21738.1 - 0.081 13.2 13.8 0.092 13.0 1.1 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat HTH_WhiA PF02650.14 KKK21738.1 - 0.083 13.2 1.5 0.18 12.1 0.3 2.1 2 0 0 2 2 2 0 WhiA C-terminal HTH domain TPR_16 PF13432.6 KKK21738.1 - 0.84 10.3 5.2 14 6.4 0.3 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat RRP36 PF06102.12 KKK21739.1 - 3.4e-49 167.0 21.1 3.4e-49 167.0 21.1 2.1 2 0 0 2 2 2 1 rRNA biogenesis protein RRP36 RNA_pol_L_2 PF13656.6 KKK21741.1 - 1.7e-33 114.2 0.0 2.3e-33 113.8 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 KKK21741.1 - 3.2e-15 55.3 0.0 6.5e-15 54.3 0.0 1.5 2 0 0 2 2 2 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Vta1_C PF18097.1 KKK21741.1 - 0.11 12.2 0.1 0.24 11.2 0.1 1.6 1 0 0 1 1 1 0 Vta1 C-terminal domain Complex1_LYR_2 PF13233.6 KKK21742.1 - 1.1e-06 29.3 2.4 1.9e-06 28.5 2.4 1.4 1 1 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 KKK21742.1 - 0.00045 20.2 3.4 0.0015 18.5 3.4 1.9 1 1 0 1 1 1 1 Complex 1 protein (LYR family) IKKbetaNEMObind PF12179.8 KKK21742.1 - 0.092 12.8 0.0 0.85 9.7 0.0 2.2 2 0 0 2 2 2 0 I-kappa-kinase-beta NEMO binding domain DNA_pol_A_exo1 PF01612.20 KKK21744.1 - 3.3e-41 140.9 0.0 6.2e-41 140.0 0.0 1.5 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.12 KKK21744.1 - 5.6e-30 103.9 1.4 4.5e-29 101.0 1.9 2.4 2 0 0 2 2 2 1 PMC2NT (NUC016) domain HRDC PF00570.23 KKK21744.1 - 1e-10 41.4 0.1 4.1e-10 39.5 0.0 2.2 2 0 0 2 2 2 1 HRDC domain ORC6 PF05460.13 KKK21744.1 - 1.8 7.7 11.5 4.2 6.5 11.5 1.5 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) DnaJ-X PF14308.6 KKK21757.1 - 2.8e-72 242.6 5.5 6.4e-72 241.4 5.5 1.6 1 0 0 1 1 1 1 X-domain of DnaJ-containing DnaJ PF00226.31 KKK21757.1 - 1.3e-25 89.2 0.1 3.5e-25 87.9 0.1 1.8 1 0 0 1 1 1 1 DnaJ domain Hemerythrin PF01814.23 KKK21758.1 - 4.9e-06 27.2 0.2 8.5e-06 26.4 0.2 1.6 1 1 0 1 1 1 1 Hemerythrin HHE cation binding domain SQS_PSY PF00494.19 KKK21759.1 - 2.1e-37 129.1 0.0 3.6e-37 128.3 0.0 1.4 1 0 0 1 1 1 1 Squalene/phytoene synthase Peroxin-22 PF12827.7 KKK21759.1 - 0.057 13.4 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Peroxisomal biogenesis protein family adh_short_C2 PF13561.6 KKK21760.1 - 3.5e-55 187.1 0.0 4.4e-55 186.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KKK21760.1 - 2.8e-51 173.8 0.1 4.6e-51 173.1 0.0 1.3 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 KKK21760.1 - 1.9e-09 37.7 0.1 3.7e-09 36.7 0.0 1.5 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 KKK21760.1 - 5e-06 26.2 0.0 7.3e-06 25.6 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KKK21760.1 - 0.0011 18.4 0.0 0.0016 17.9 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase ADH_zinc_N PF00107.26 KKK21760.1 - 0.0035 17.3 0.0 0.0062 16.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase RmlD_sub_bind PF04321.17 KKK21760.1 - 0.041 13.0 0.0 0.1 11.6 0.0 1.7 1 1 0 1 1 1 0 RmlD substrate binding domain Fungal_trans PF04082.18 KKK21761.1 - 2.9e-25 88.8 2.0 4.3e-25 88.2 2.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK21761.1 - 1.7e-06 28.1 6.7 3.6e-06 27.0 6.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cerato-platanin PF07249.12 KKK21762.1 - 5.8e-27 94.2 1.7 2.7e-24 85.5 1.7 2.0 1 1 0 1 1 1 1 Cerato-platanin Glyco_hydro_16 PF00722.21 KKK21763.1 - 2.8e-07 30.2 0.0 4.8e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Sugar_tr PF00083.24 KKK21764.1 - 1e-79 268.6 21.0 1.2e-79 268.3 21.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKK21764.1 - 7.2e-25 87.7 31.8 1.1e-23 83.7 31.8 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KKK21764.1 - 1.3e-07 30.4 2.2 2.1e-07 29.8 2.2 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) zf-H2C2 PF09337.10 KKK21765.1 - 3.2e-17 62.5 2.3 6.7e-17 61.4 2.3 1.6 1 0 0 1 1 1 1 H2C2 zinc finger Integrase_H2C2 PF17921.1 KKK21765.1 - 4.9e-10 39.4 1.1 1.1e-09 38.2 1.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain Acetyltransf_1 PF00583.25 KKK21765.1 - 9.1e-07 29.1 0.0 1.5e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 KKK21765.1 - 0.0026 17.7 0.0 0.0051 16.8 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 KKK21765.1 - 0.0034 18.1 0.1 0.0084 16.8 0.1 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KKK21765.1 - 0.063 13.4 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain HK PF02110.15 KKK21766.1 - 4.3e-79 265.4 0.3 4.3e-79 265.4 0.3 1.8 2 1 2 4 4 4 1 Hydroxyethylthiazole kinase family TMP-TENI PF02581.17 KKK21766.1 - 1.2e-57 194.2 2.4 1.9e-57 193.5 2.4 1.4 1 0 0 1 1 1 1 Thiamine monophosphate synthase Carb_kinase PF01256.17 KKK21766.1 - 0.011 15.2 0.9 0.019 14.5 0.0 1.8 2 0 0 2 2 2 0 Carbohydrate kinase Beta-lactamase PF00144.24 KKK21767.1 - 1.3e-28 100.3 1.1 2e-28 99.6 1.1 1.2 1 0 0 1 1 1 1 Beta-lactamase Peptidase_S9 PF00326.21 KKK21768.1 - 2.1e-39 135.2 0.7 2.9e-39 134.8 0.7 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.18 KKK21768.1 - 1.5e-11 44.2 0.1 6.4e-11 42.2 0.1 1.9 1 1 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S15 PF02129.18 KKK21768.1 - 1.1e-09 38.3 3.6 1e-05 25.3 2.1 2.4 1 1 0 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.8 KKK21768.1 - 1.1e-07 31.3 2.6 0.0012 18.1 0.0 2.5 3 0 0 3 3 3 2 Serine aminopeptidase, S33 BAAT_C PF08840.11 KKK21768.1 - 1.1e-06 28.7 0.1 1e-05 25.6 0.1 2.1 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_1 PF00561.20 KKK21768.1 - 1.9e-06 27.8 0.4 0.013 15.2 0.0 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 KKK21768.1 - 2.1e-05 24.6 0.0 0.00024 21.2 0.0 2.2 2 0 0 2 2 2 1 TAP-like protein PD40 PF07676.12 KKK21768.1 - 2.3e-05 24.2 2.2 0.00029 20.7 0.6 2.8 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat Abhydrolase_3 PF07859.13 KKK21768.1 - 8.5e-05 22.5 2.2 0.00076 19.4 2.2 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 KKK21768.1 - 0.0011 18.8 0.1 0.046 13.5 0.0 2.3 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase DUF829 PF05705.14 KKK21768.1 - 0.0073 16.2 0.0 0.011 15.7 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Esterase_phd PF10503.9 KKK21768.1 - 0.009 15.5 0.8 0.059 12.8 0.6 2.4 2 1 0 2 2 2 1 Esterase PHB depolymerase COesterase PF00135.28 KKK21768.1 - 0.036 13.0 0.1 0.054 12.4 0.1 1.2 1 0 0 1 1 1 0 Carboxylesterase family FSH1 PF03959.13 KKK21768.1 - 0.049 13.3 0.0 0.087 12.5 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) LIP PF03583.14 KKK21768.1 - 0.08 12.3 1.7 2.2 7.5 0.0 2.2 2 0 0 2 2 2 0 Secretory lipase Beta-lactamase PF00144.24 KKK21769.1 - 4.8e-42 144.4 0.2 6.6e-42 143.9 0.2 1.1 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.8 KKK21769.1 - 4.2e-12 46.4 0.0 1.2e-11 45.0 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3471) CoA_transf_3 PF02515.17 KKK21770.1 - 7.6e-40 137.2 0.4 1.1e-38 133.4 0.0 2.1 2 0 0 2 2 2 2 CoA-transferase family III Lipocalin_9 PF17186.4 KKK21771.1 - 4.7e-08 33.4 0.0 1.1e-07 32.2 0.0 1.6 1 0 0 1 1 1 1 Lipocalin-like domain Aconitase PF00330.20 KKK21773.1 - 5.4e-145 483.9 0.0 6.9e-145 483.6 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KKK21773.1 - 4.4e-39 133.8 0.0 6.8e-39 133.2 0.0 1.3 1 0 0 1 1 1 1 Aconitase C-terminal domain DUF3425 PF11905.8 KKK21774.1 - 3.5e-23 81.9 0.0 5.4e-23 81.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) FAM199X PF15814.5 KKK21774.1 - 0.026 13.6 0.1 0.035 13.2 0.1 1.2 1 0 0 1 1 1 0 Protein family FAM199X bZIP_1 PF00170.21 KKK21774.1 - 0.041 14.0 8.6 0.1 12.7 8.6 1.6 1 0 0 1 1 1 0 bZIP transcription factor CSTF1_dimer PF16699.5 KKK21774.1 - 0.19 11.5 0.1 0.33 10.7 0.1 1.3 1 0 0 1 1 1 0 Cleavage stimulation factor subunit 1, dimerisation domain Rad4 PF03835.15 KKK21775.1 - 4.4e-35 120.5 0.1 1.6e-34 118.7 0.0 2.0 2 0 0 2 2 2 1 Rad4 transglutaminase-like domain BHD_3 PF10405.9 KKK21775.1 - 9.2e-29 99.7 0.4 2.8e-28 98.1 0.4 1.9 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.9 KKK21775.1 - 1.2e-21 76.3 0.0 2.4e-21 75.3 0.0 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.9 KKK21775.1 - 9.4e-17 61.7 0.2 9.4e-17 61.7 0.2 3.3 3 1 0 3 3 3 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.19 KKK21775.1 - 0.018 15.5 0.0 0.072 13.5 0.0 2.1 1 0 0 1 1 1 0 Transglutaminase-like superfamily Geminin PF07412.12 KKK21775.1 - 0.027 14.2 1.1 0.081 12.7 1.1 1.8 1 0 0 1 1 1 0 Geminin FAA_hydrolase PF01557.18 KKK21776.1 - 2.8e-52 177.5 0.0 3.9e-52 177.1 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family DUF3712 PF12505.8 KKK21777.1 - 1.2e-33 116.0 0.4 2.2e-33 115.1 0.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3712) Adenyl_transf PF04439.12 KKK21777.1 - 0.14 11.2 0.1 0.21 10.7 0.1 1.1 1 0 0 1 1 1 0 Streptomycin adenylyltransferase Zn_clus PF00172.18 KKK21778.1 - 1.4e-09 37.9 6.3 3.6e-09 36.6 6.3 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 KKK21779.1 - 1.1e-14 54.1 48.5 1.9e-08 33.7 30.1 2.7 2 1 1 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.13 KKK21779.1 - 4.8e-08 31.9 23.0 1.1e-06 27.4 23.2 2.2 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) GtrA PF04138.14 KKK21779.1 - 0.00039 20.6 7.0 0.00039 20.6 7.0 4.0 4 2 0 4 4 4 1 GtrA-like protein Trp_oprn_chp PF09534.10 KKK21779.1 - 0.031 14.1 0.4 0.031 14.1 0.4 2.1 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Copper-fist PF00649.18 KKK21780.1 - 2.1e-17 62.3 0.5 7.3e-17 60.6 0.5 2.0 1 0 0 1 1 1 1 Copper fist DNA binding domain HsbA PF12296.8 KKK21781.1 - 5.6e-26 91.3 13.3 5.6e-26 91.3 13.3 2.5 2 0 0 2 2 2 1 Hydrophobic surface binding protein A NPV_P10 PF05531.12 KKK21781.1 - 0.6 10.6 5.8 5.4 7.6 5.8 2.5 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein RIFIN PF02009.16 KKK21781.1 - 1.7 8.5 11.2 2.6 7.9 11.2 1.2 1 0 0 1 1 1 0 Rifin tRNA-synt_1b PF00579.25 KKK21782.1 - 4.6e-24 85.2 0.0 8.6e-24 84.4 0.0 1.4 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) PIN_12 PF16289.5 KKK21782.1 - 0.12 12.9 0.5 0.63 10.5 0.0 2.2 2 0 0 2 2 2 0 PIN domain tRNA_bind PF01588.20 KKK21783.1 - 4.8e-21 74.7 0.0 4e-20 71.7 0.0 2.3 1 1 0 1 1 1 1 Putative tRNA binding domain GST_C_2 PF13410.6 KKK21783.1 - 5.3e-05 23.2 0.0 9.4e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KKK21783.1 - 0.0012 19.0 0.0 0.0012 19.0 0.0 2.9 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KKK21783.1 - 0.37 11.0 1.6 0.4 10.9 0.0 1.9 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain APH PF01636.23 KKK21784.1 - 1.5e-08 34.9 0.0 2.2e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KKK21784.1 - 0.17 11.4 0.0 0.3 10.6 0.0 1.5 2 0 0 2 2 2 0 Choline/ethanolamine kinase Pkinase PF00069.25 KKK21785.1 - 1.5e-53 181.9 0.1 3.9e-48 164.1 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KKK21785.1 - 1.2e-33 116.5 0.1 3.1e-32 111.9 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 KKK21785.1 - 8.9e-08 31.8 0.0 2e-07 30.6 0.0 1.5 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KKK21785.1 - 0.0031 17.5 0.1 0.0066 16.4 0.1 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KKK21785.1 - 0.0068 15.2 0.0 0.016 14.0 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase Sybindin PF04099.12 KKK21786.1 - 2.2e-25 89.2 0.0 3e-25 88.8 0.0 1.1 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 KKK21786.1 - 0.0021 18.2 0.1 0.0031 17.6 0.1 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region SRI PF08236.11 KKK21787.1 - 8.7e-21 73.9 15.4 2e-20 72.7 15.4 1.7 1 0 0 1 1 1 1 SRI (Set2 Rpb1 interacting) domain SET PF00856.28 KKK21787.1 - 1.7e-16 61.0 4.3 2.4e-16 60.6 0.3 3.0 2 1 0 2 2 2 1 SET domain AWS PF17907.1 KKK21787.1 - 3.2e-10 39.9 9.4 3.2e-10 39.9 9.4 2.4 2 0 0 2 2 2 1 AWS domain WW PF00397.26 KKK21787.1 - 0.016 15.3 0.7 0.048 13.7 0.7 2.0 1 0 0 1 1 1 0 WW domain Pox_H7 PF04787.12 KKK21787.1 - 0.18 12.3 2.9 0.37 11.3 2.9 1.4 1 0 0 1 1 1 0 Late protein H7 AT_hook PF02178.19 KKK21788.1 - 0.032 14.1 1.5 0.032 14.1 1.5 2.7 2 0 0 2 2 2 0 AT hook motif Myb_DNA-binding PF00249.31 KKK21788.1 - 0.05 13.8 0.0 0.12 12.6 0.0 1.6 1 1 0 1 1 1 0 Myb-like DNA-binding domain eIF-6 PF01912.18 KKK21789.1 - 9.4e-28 96.9 0.3 1.3e-27 96.4 0.2 1.3 2 0 0 2 2 2 1 eIF-6 family Brix PF04427.18 KKK21790.1 - 1.4e-24 87.3 0.0 2.4e-24 86.5 0.0 1.3 1 0 0 1 1 1 1 Brix domain CDC45 PF02724.14 KKK21790.1 - 0.062 11.6 13.6 0.078 11.3 13.6 1.2 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.10 KKK21790.1 - 0.12 11.7 21.2 0.17 11.2 21.2 1.1 1 0 0 1 1 1 0 BUD22 Sporozoite_P67 PF05642.11 KKK21790.1 - 0.31 9.1 7.2 0.41 8.7 7.2 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Nop14 PF04147.12 KKK21790.1 - 0.68 8.1 17.9 0.9 7.7 17.9 1.1 1 0 0 1 1 1 0 Nop14-like family Pept_tRNA_hydro PF01195.19 KKK21791.1 - 7.6e-20 71.6 0.0 8.4e-12 45.4 0.0 3.0 2 1 0 2 2 2 2 Peptidyl-tRNA hydrolase HGTP_anticodon PF03129.20 KKK21792.1 - 8.5e-19 67.5 2.1 1.2e-18 67.1 0.0 2.4 3 0 0 3 3 3 1 Anticodon binding domain tRNA-synt_2b PF00587.25 KKK21792.1 - 7.2e-08 32.6 0.0 2.5e-07 30.8 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) BAR PF03114.18 KKK21793.1 - 4e-60 203.4 2.8 4.9e-60 203.1 2.8 1.1 1 0 0 1 1 1 1 BAR domain CP12 PF02672.15 KKK21793.1 - 0.021 15.6 0.0 0.11 13.2 0.0 2.3 2 1 0 2 2 2 0 CP12 domain EspB_PE PF18625.1 KKK21793.1 - 1.2 9.7 5.1 21 5.7 0.6 2.8 3 0 0 3 3 3 0 ESX-1 secreted protein B PE domain SVIP PF15811.5 KKK21793.1 - 3.6 8.1 7.1 0.32 11.5 1.3 2.3 2 1 0 2 2 2 0 Small VCP/p97-interacting protein Jnk-SapK_ap_N PF09744.9 KKK21793.1 - 4.8 7.4 10.9 29 4.8 7.1 3.0 2 2 0 2 2 2 0 JNK_SAPK-associated protein-1 Pkinase PF00069.25 KKK21794.1 - 4.2e-49 167.3 0.0 7.4e-49 166.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK21794.1 - 3.8e-27 95.2 0.0 5.5e-27 94.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KKK21794.1 - 0.0021 17.4 0.0 0.0035 16.7 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KKK21794.1 - 0.003 16.9 0.0 0.006 16.0 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KKK21794.1 - 0.1 12.5 0.4 0.85 9.5 0.0 2.4 2 1 1 3 3 3 0 Phosphotransferase enzyme family NAD_kinase PF01513.21 KKK21798.1 - 1.9e-67 227.5 0.0 6.6e-67 225.8 0.0 1.8 1 1 0 1 1 1 1 ATP-NAD kinase E1-E2_ATPase PF00122.20 KKK21800.1 - 5.3e-41 140.1 8.0 1e-37 129.4 8.0 3.0 1 1 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 KKK21800.1 - 2.8e-29 102.1 1.1 2.8e-29 102.1 1.1 2.5 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KKK21800.1 - 1.2e-16 61.6 0.5 2.8e-13 50.6 0.0 2.6 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KKK21800.1 - 2.5e-14 52.7 0.0 6.9e-14 51.3 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 KKK21800.1 - 1.3e-13 50.8 0.0 2.6e-13 49.8 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KKK21800.1 - 2.3e-07 30.8 1.9 7.3e-06 25.9 0.9 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF2463 PF09591.10 KKK21800.1 - 0.037 13.9 0.5 0.037 13.9 0.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2463) HAD PF12710.7 KKK21800.1 - 0.088 13.2 0.1 0.18 12.2 0.1 1.5 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase DEAD PF00270.29 KKK21801.1 - 5.3e-34 117.5 0.3 1.8e-33 115.8 0.1 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KKK21801.1 - 2.4e-23 82.6 0.2 7.4e-23 81.0 0.2 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_30 PF13604.6 KKK21801.1 - 0.0066 16.2 0.1 0.016 14.9 0.0 1.6 2 0 0 2 2 2 1 AAA domain SH3_9 PF14604.6 KKK21802.1 - 6.5e-25 86.8 0.3 2e-12 46.8 0.1 2.4 2 0 0 2 2 2 2 Variant SH3 domain FCH PF00611.23 KKK21802.1 - 7.3e-23 80.7 0.2 2.5e-22 78.9 0.0 2.1 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.28 KKK21802.1 - 4.6e-18 64.5 0.1 2.6e-08 33.4 0.0 2.4 2 0 0 2 2 2 2 SH3 domain C1_1 PF00130.22 KKK21802.1 - 1.4e-15 56.9 5.2 2.8e-15 56.0 5.2 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SH3_10 PF17902.1 KKK21802.1 - 0.00011 22.2 0.0 0.36 10.9 0.0 2.8 2 0 0 2 2 2 2 SH3 domain C1_2 PF03107.16 KKK21802.1 - 0.00021 21.5 3.3 0.00041 20.6 3.3 1.4 1 0 0 1 1 1 1 C1 domain SH3_2 PF07653.17 KKK21802.1 - 0.0024 17.5 0.0 0.12 12.0 0.0 2.4 2 0 0 2 2 2 1 Variant SH3 domain SH3_3 PF08239.11 KKK21802.1 - 0.012 15.9 0.2 0.12 12.6 0.0 2.3 2 0 0 2 2 2 0 Bacterial SH3 domain FYVE PF01363.21 KKK21802.1 - 0.13 12.5 3.1 0.29 11.3 3.1 1.5 1 0 0 1 1 1 0 FYVE zinc finger Cortex-I_coil PF09304.10 KKK21802.1 - 2 8.7 15.5 1.1 9.5 0.0 4.0 4 0 0 4 4 4 0 Cortexillin I, coiled coil DUF2014 PF09427.10 KKK21803.1 - 1.9e-99 332.3 0.0 3e-99 331.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF2014) HLH PF00010.26 KKK21803.1 - 5.5e-18 64.7 0.1 1.3e-17 63.5 0.1 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain bZIP_1 PF00170.21 KKK21803.1 - 0.01 15.9 2.9 0.011 15.8 1.0 2.0 2 0 0 2 2 2 0 bZIP transcription factor ZapB PF06005.12 KKK21803.1 - 0.11 13.0 1.5 0.21 12.0 0.3 2.1 2 0 0 2 2 2 0 Cell division protein ZapB GTP_CH_N PF12471.8 KKK21804.1 - 1.3e-88 295.8 0.0 2e-88 295.2 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal DHDPS PF00701.22 KKK21804.1 - 2.2e-37 128.3 0.0 3.5e-37 127.7 0.0 1.3 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family GTP_cyclohydro2 PF00925.20 KKK21804.1 - 6.1e-18 64.9 0.0 9.7e-18 64.3 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase II NTP_transf_9 PF04248.12 KKK21804.1 - 0.16 11.9 0.0 0.34 10.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF427) FSH1 PF03959.13 KKK21805.1 - 9.9e-30 103.8 0.0 7.1e-29 101.0 0.0 2.2 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Ferric_reduct PF01794.19 KKK21806.1 - 2.4e-21 76.2 13.0 7.3e-21 74.6 13.0 1.9 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KKK21806.1 - 4.1e-16 59.5 0.0 1.5e-15 57.6 0.0 1.9 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KKK21806.1 - 3.1e-13 49.8 0.0 2.1e-10 40.6 0.0 2.6 2 0 0 2 2 2 2 FAD-binding domain NAD_binding_1 PF00175.21 KKK21806.1 - 0.025 15.2 0.2 1.5 9.5 0.0 2.3 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain DUF4153 PF13687.6 KKK21806.1 - 1.5 8.4 18.2 0.37 10.4 13.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4153) NAD_binding_10 PF13460.6 KKK21808.1 - 5.3e-13 49.3 0.0 1.5e-12 47.8 0.0 1.7 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KKK21808.1 - 1.9e-06 27.6 0.0 9.7e-06 25.3 0.0 1.9 2 0 0 2 2 2 1 NmrA-like family NAD_binding_4 PF07993.12 KKK21808.1 - 0.017 14.3 0.1 0.026 13.7 0.1 1.2 1 0 0 1 1 1 0 Male sterility protein Semialdhyde_dh PF01118.24 KKK21808.1 - 0.033 14.6 0.0 0.058 13.8 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 KKK21808.1 - 0.061 13.6 0.0 0.12 12.6 0.0 1.5 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Methyltransf_2 PF00891.18 KKK21809.1 - 1.4e-23 83.3 0.0 3.5e-23 82.0 0.0 1.6 1 0 0 1 1 1 1 O-methyltransferase domain NAD_binding_10 PF13460.6 KKK21809.1 - 7.5e-20 71.6 0.0 1.2e-19 71.0 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KKK21809.1 - 4.7e-06 26.3 0.1 8.9e-06 25.4 0.1 1.4 1 0 0 1 1 1 1 NmrA-like family Dimerisation2 PF16864.5 KKK21809.1 - 7.4e-05 22.7 0.1 0.00027 20.8 0.0 1.9 2 0 0 2 2 2 1 Dimerisation domain Epimerase PF01370.21 KKK21809.1 - 0.00014 21.4 0.0 0.00023 20.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KKK21809.1 - 0.013 14.5 0.0 0.019 14.0 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Dimerisation PF08100.11 KKK21809.1 - 0.015 15.3 0.0 0.042 13.9 0.0 1.8 1 0 0 1 1 1 0 Dimerisation domain Semialdhyde_dh PF01118.24 KKK21809.1 - 0.033 14.6 0.0 0.07 13.6 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Questin_oxidase PF14027.6 KKK21810.1 - 3.6e-88 296.4 0.0 4.5e-88 296.0 0.0 1.1 1 0 0 1 1 1 1 Questin oxidase-like DUF433 PF04255.14 KKK21810.1 - 0.027 14.3 0.0 0.084 12.7 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF433) DUF1772 PF08592.11 KKK21811.1 - 1.8e-29 102.8 3.0 2.1e-29 102.6 3.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) GMC_oxred_N PF00732.19 KKK21812.1 - 2.8e-52 177.9 0.0 3.7e-52 177.5 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KKK21812.1 - 1.5e-34 119.6 0.0 2.4e-34 118.9 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_3 PF13738.6 KKK21812.1 - 1.8e-07 30.8 0.2 0.0077 15.5 0.4 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KKK21812.1 - 5.5e-07 29.0 1.6 9.6e-05 21.6 1.3 2.1 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 KKK21812.1 - 1.9e-06 27.7 2.6 2.7e-05 23.9 2.6 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KKK21812.1 - 0.00017 21.7 0.0 0.00046 20.4 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KKK21812.1 - 0.00042 19.6 0.1 0.37 10.0 0.1 2.2 2 0 0 2 2 2 2 Thi4 family Pyr_redox_2 PF07992.14 KKK21812.1 - 0.00043 19.6 0.7 0.0038 16.5 0.3 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KKK21812.1 - 0.001 18.2 0.3 0.0015 17.6 0.3 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Trp_halogenase PF04820.14 KKK21812.1 - 0.043 12.7 0.0 0.062 12.1 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase FAD_binding_3 PF01494.19 KKK21812.1 - 0.043 13.0 0.2 0.082 12.1 0.2 1.4 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.27 KKK21812.1 - 0.064 13.8 2.5 1.5 9.4 0.6 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KKK21812.1 - 0.093 12.7 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding TrkA_N PF02254.18 KKK21812.1 - 0.099 12.9 0.6 0.21 11.9 0.1 1.8 2 0 0 2 2 2 0 TrkA-N domain p450 PF00067.22 KKK21813.1 - 1.2e-62 212.2 0.0 1.5e-62 211.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 TrmB PF01978.19 KKK21814.1 - 0.18 11.7 0.0 0.41 10.6 0.0 1.5 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Dabb PF07876.12 KKK21815.1 - 0.00039 21.0 0.2 0.76 10.4 0.1 2.2 1 1 1 2 2 2 2 Stress responsive A/B Barrel Domain adh_short PF00106.25 KKK21816.1 - 4.4e-22 78.5 0.0 6e-22 78.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KKK21816.1 - 6.9e-15 55.2 0.1 6.4e-14 52.1 0.1 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 KKK21816.1 - 0.097 12.1 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DNA_pol_lambd_f PF10391.9 KKK21816.1 - 0.16 11.9 0.1 0.37 10.7 0.1 1.6 1 0 0 1 1 1 0 Fingers domain of DNA polymerase lambda KR PF08659.10 KKK21816.1 - 0.74 9.7 6.3 3.1 7.7 1.6 3.3 3 1 0 3 3 3 0 KR domain p450 PF00067.22 KKK21817.1 - 1.4e-62 212.0 0.0 1.7e-62 211.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF1729 PF08354.10 KKK21818.1 - 2.7e-142 473.8 0.0 2.9e-141 470.5 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1729) Acyl_transf_1 PF00698.21 KKK21818.1 - 3.1e-88 296.3 0.3 4.4e-85 286.0 0.0 3.1 2 1 1 3 3 3 2 Acyl transferase domain MaoC_dehydratas PF01575.19 KKK21818.1 - 2.9e-26 91.5 0.0 6.9e-26 90.2 0.0 1.6 1 0 0 1 1 1 1 MaoC like domain SAT PF16073.5 KKK21818.1 - 8.7e-21 74.7 0.3 1.9e-20 73.6 0.3 1.5 1 0 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis FAS_meander PF17951.1 KKK21818.1 - 1.3e-11 44.5 0.0 2.4e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 Fatty acid synthase meander beta sheet domain MaoC_dehydrat_N PF13452.6 KKK21818.1 - 3.5e-09 36.9 0.1 6e-08 32.9 0.0 2.4 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase Fas_alpha_ACP PF18325.1 KKK21819.1 - 1.3e-47 162.2 0.0 2.7e-47 161.1 0.0 1.6 1 0 0 1 1 1 1 Fatty acid synthase subunit alpha Acyl carrier domain ketoacyl-synt PF00109.26 KKK21819.1 - 1.5e-26 93.5 0.2 3.3e-26 92.4 0.2 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain FAS_I_H PF18314.1 KKK21819.1 - 3.4e-26 92.2 0.6 2.5e-25 89.3 0.6 2.1 1 1 0 1 1 1 1 Fatty acid synthase type I helical domain Ketoacyl-synt_C PF02801.22 KKK21819.1 - 3.4e-14 52.9 0.0 9.6e-14 51.4 0.0 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ACPS PF01648.20 KKK21819.1 - 1.3e-11 44.6 0.0 3.6e-11 43.2 0.0 1.8 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily KR PF08659.10 KKK21819.1 - 0.0044 16.9 0.0 0.013 15.4 0.0 1.8 1 0 0 1 1 1 1 KR domain adh_short PF00106.25 KKK21819.1 - 0.008 15.6 0.0 0.67 9.4 0.0 3.0 3 0 0 3 3 3 1 short chain dehydrogenase Abhydrolase_3 PF07859.13 KKK21820.1 - 1.7e-46 158.8 0.1 2e-46 158.5 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.20 KKK21820.1 - 0.00057 20.1 0.0 0.0007 19.8 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Say1_Mug180 PF10340.9 KKK21820.1 - 0.0016 17.4 0.0 0.0022 16.9 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase Hydrolase_4 PF12146.8 KKK21820.1 - 0.0052 16.1 0.0 0.013 14.7 0.0 1.7 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KKK21820.1 - 0.011 15.4 0.0 0.015 15.0 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold AflR PF08493.10 KKK21821.1 - 4.2e-49 167.6 0.2 5.4e-49 167.2 0.2 1.1 1 0 0 1 1 1 1 Aflatoxin regulatory protein Ofd1_CTDD PF10637.9 KKK21825.1 - 5.9e-103 343.7 0.0 6.9e-99 330.3 0.0 2.3 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_4 PF13661.6 KKK21825.1 - 1.8e-26 92.6 0.0 4.6e-26 91.3 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 KKK21825.1 - 1.8e-14 54.4 0.0 5.4e-14 52.9 0.0 1.9 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily HLH PF00010.26 KKK21826.1 - 5.7e-16 58.2 1.1 1.5e-15 56.9 0.8 1.8 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Fzo_mitofusin PF04799.13 KKK21826.1 - 0.35 10.4 1.8 0.57 9.7 1.8 1.2 1 0 0 1 1 1 0 fzo-like conserved region Nup88 PF10168.9 KKK21827.1 - 0.18 9.6 0.7 0.25 9.1 0.7 1.1 1 0 0 1 1 1 0 Nuclear pore component E1-E2_ATPase PF00122.20 KKK21839.1 - 5.3e-38 130.3 0.7 5.3e-38 130.3 0.7 3.3 3 1 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 KKK21839.1 - 9.6e-18 65.2 0.6 3e-17 63.6 0.0 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KKK21839.1 - 6.2e-10 38.6 0.0 1.4e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KKK21839.1 - 0.0048 16.7 0.1 0.0095 15.7 0.1 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase zf-H2C2_2 PF13465.6 KKK21840.1 - 2.4e-09 37.2 7.2 0.00045 20.5 0.1 3.1 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.26 KKK21840.1 - 2.5e-05 24.5 23.5 0.0081 16.6 6.8 4.1 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KKK21840.1 - 5.1e-05 23.8 18.0 0.058 14.3 5.2 4.3 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KKK21840.1 - 0.83 9.5 6.7 9.7 6.1 2.1 2.6 2 0 0 2 2 2 0 zinc-finger C2H2-type Bunya_G2 PF03563.13 KKK21840.1 - 1.6 7.9 3.8 2.6 7.2 3.8 1.2 1 0 0 1 1 1 0 Bunyavirus glycoprotein G2 zf-C2H2_6 PF13912.6 KKK21840.1 - 4.2 7.5 8.6 26 5.0 0.1 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger Ribonuclease_T2 PF00445.18 KKK21841.1 - 4.6e-44 150.8 0.9 8.4e-44 150.0 0.9 1.4 1 0 0 1 1 1 1 Ribonuclease T2 family GT-D PF08759.11 KKK21841.1 - 0.076 12.7 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase GT-D fold DUF155 PF02582.14 KKK21842.1 - 1.3e-47 162.2 0.0 1.8e-47 161.7 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Clathrin PF00637.20 KKK21843.1 - 1.3e-21 76.9 0.3 4.3e-19 68.8 0.1 3.2 2 1 1 3 3 3 1 Region in Clathrin and VPS Vps39_1 PF10366.9 KKK21843.1 - 0.013 15.7 0.1 0.039 14.2 0.1 1.7 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 1 PQQ_3 PF13570.6 KKK21843.1 - 0.018 15.5 0.2 0.32 11.5 0.0 2.8 2 0 0 2 2 2 0 PQQ-like domain TPR_14 PF13428.6 KKK21843.1 - 0.057 14.3 2.0 5.9 8.0 0.2 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 KKK21843.1 - 0.061 13.4 0.5 4.5 7.5 0.2 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 KKK21843.1 - 0.073 13.2 0.1 2.6 8.4 0.6 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat WD40_like PF17005.5 KKK21843.1 - 0.077 12.3 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 WD40-like domain zf-RING_5 PF14634.6 KKK21843.1 - 0.16 12.0 0.8 0.32 11.0 0.8 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_11 PF17123.5 KKK21843.1 - 0.39 10.5 1.6 0.96 9.3 1.6 1.7 1 0 0 1 1 1 0 RING-like zinc finger CP2 PF04516.15 KKK21844.1 - 1.6e-90 302.4 0.0 2.8e-90 301.7 0.0 1.4 1 0 0 1 1 1 1 CP2 transcription factor APH PF01636.23 KKK21845.1 - 0.00027 20.9 0.0 0.001 19.0 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pectinesterase PF01095.19 KKK21846.1 - 2.4e-25 88.9 1.1 2.4e-20 72.5 0.3 2.1 2 0 0 2 2 2 2 Pectinesterase TFIIS_M PF07500.14 KKK21847.1 - 1.1e-27 96.7 1.0 1.8e-27 96.0 0.1 1.8 2 1 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.18 KKK21847.1 - 1.8e-18 66.1 5.9 2.9e-18 65.4 5.9 1.4 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.11 KKK21847.1 - 2.1e-10 40.5 0.3 2.1e-10 40.5 0.3 1.9 2 0 0 2 2 2 1 TFIIS helical bundle-like domain Baculo_LEF5_C PF11792.8 KKK21847.1 - 0.029 14.0 2.1 0.043 13.5 0.2 2.1 2 0 0 2 2 2 0 Baculoviridae late expression factor 5 C-terminal domain DUF4522 PF15022.6 KKK21847.1 - 0.061 13.6 3.0 3.2 8.0 0.4 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF4522) MRPL52 PF18699.1 KKK21847.1 - 0.49 10.6 0.1 0.49 10.6 0.1 2.6 3 0 0 3 3 3 0 Mitoribosomal protein mL52 DUF4615 PF15393.6 KKK21847.1 - 3.1 8.4 8.2 0.16 12.6 1.8 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4615) LRR_6 PF13516.6 KKK21848.1 - 1.8e-14 52.5 1.2 0.0031 17.5 0.0 7.8 8 0 0 8 8 8 3 Leucine Rich repeat LRR_4 PF12799.7 KKK21848.1 - 3.6e-05 24.0 6.7 0.36 11.3 0.3 5.1 5 1 0 5 5 5 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KKK21848.1 - 0.01 15.5 7.0 0.81 9.5 0.0 4.7 4 1 0 4 4 4 0 Leucine rich repeat NOA36 PF06524.12 KKK21848.1 - 1.7 7.9 15.5 2.6 7.3 15.5 1.2 1 0 0 1 1 1 0 NOA36 protein Nop14 PF04147.12 KKK21848.1 - 2.7 6.1 25.5 3.8 5.6 25.5 1.1 1 0 0 1 1 1 0 Nop14-like family Drc1-Sld2 PF11719.8 KKK21848.1 - 5 6.6 16.4 6.5 6.2 16.4 1.1 1 0 0 1 1 1 0 DNA replication and checkpoint protein RNA_pol_Rpc4 PF05132.14 KKK21848.1 - 5.4 7.4 6.4 9.6 6.6 6.4 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 GOLD_2 PF13897.6 KKK21848.1 - 6.1 7.3 9.8 14 6.2 9.8 1.6 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking SDA1 PF05285.12 KKK21848.1 - 7.6 5.9 25.6 10 5.5 25.6 1.2 1 0 0 1 1 1 0 SDA1 RRM_1 PF00076.22 KKK21849.1 - 7.3e-43 144.3 0.0 4.2e-20 71.3 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KKK21849.1 - 4.5e-05 23.5 0.0 0.3 11.2 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 KKK21849.1 - 0.016 15.2 0.0 5.2 7.2 0.0 2.5 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 KKK21849.1 - 0.072 13.0 0.0 5.5 6.9 0.0 2.3 2 0 0 2 2 2 0 Occluded RNA-recognition motif Alg6_Alg8 PF03155.15 KKK21850.1 - 1.1e-131 440.2 17.8 1e-83 282.0 8.9 2.1 2 0 0 2 2 2 2 ALG6, ALG8 glycosyltransferase family Proteasome PF00227.26 KKK21852.1 - 2.3e-50 170.7 0.1 3.2e-50 170.3 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KKK21852.1 - 5.1e-13 48.4 0.3 8.3e-13 47.8 0.3 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Amidase_5 PF05382.13 KKK21852.1 - 0.032 14.1 0.0 4 7.4 0.0 2.2 2 0 0 2 2 2 0 Bacteriophage peptidoglycan hydrolase GCP_C_terminal PF04130.13 KKK21853.1 - 2e-102 342.8 0.1 4e-102 341.8 0.1 1.5 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 KKK21853.1 - 2.2e-75 254.1 0.0 1.2e-74 251.7 0.0 2.0 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal DUF2373 PF10180.9 KKK21853.1 - 5e-19 67.9 0.1 1.1e-18 66.8 0.1 1.6 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) Stm1_N PF09598.10 KKK21854.1 - 0.95 10.4 0.0 0.95 10.4 0.0 4.3 4 1 0 4 4 4 0 Stm1 ubiquitin PF00240.23 KKK21855.1 - 4.6e-34 116.0 0.6 7.9e-34 115.2 0.6 1.4 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_S27 PF01599.19 KKK21855.1 - 7.3e-27 93.3 1.2 7.3e-27 93.3 1.2 2.0 2 0 0 2 2 2 1 Ribosomal protein S27a Rad60-SLD PF11976.8 KKK21855.1 - 2.6e-16 59.2 0.7 4.9e-16 58.3 0.7 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 KKK21855.1 - 2.8e-05 24.5 0.4 0.00013 22.4 0.1 2.1 2 1 0 2 2 2 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 KKK21855.1 - 0.0012 19.0 0.6 0.0026 17.8 0.6 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 KKK21855.1 - 0.004 17.5 0.6 0.0079 16.5 0.0 1.7 1 1 1 2 2 2 1 Ubiquitin-like domain TBK1_ULD PF18396.1 KKK21855.1 - 0.0054 16.6 0.0 0.0082 16.1 0.0 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain IBR PF01485.21 KKK21855.1 - 0.0099 16.1 0.3 0.016 15.4 0.3 1.4 1 0 0 1 1 1 1 IBR domain, a half RING-finger domain DUF2407 PF10302.9 KKK21855.1 - 0.013 16.1 0.7 0.019 15.6 0.7 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 KKK21855.1 - 0.021 14.9 1.0 5.9 7.0 0.2 2.4 2 0 0 2 2 2 0 Ubiquitin-like domain Glyco_hydro_18 PF00704.28 KKK21856.1 - 5.2e-70 236.6 2.6 1.2e-69 235.4 2.6 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 COX17 PF05051.13 KKK21857.1 - 3.1e-22 78.7 6.7 3.6e-22 78.4 6.7 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) zf-C2H2 PF00096.26 KKK21892.1 - 8.3e-20 70.1 26.3 3.6e-05 24.0 1.7 4.6 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KKK21892.1 - 4.3e-16 58.5 28.1 1.4e-06 28.5 1.5 5.4 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 KKK21892.1 - 1.1e-10 41.4 23.9 0.0041 17.9 1.3 4.7 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KKK21892.1 - 5.9e-05 23.2 0.5 12 6.3 0.0 4.2 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 KKK21892.1 - 0.002 18.7 4.9 0.24 12.0 0.7 2.9 2 1 1 3 3 3 2 FOXP coiled-coil domain zf-C2H2_11 PF16622.5 KKK21892.1 - 0.0035 17.1 10.6 0.02 14.7 0.8 3.3 3 0 0 3 3 3 2 zinc-finger C2H2-type zf-met PF12874.7 KKK21892.1 - 0.0045 17.3 12.0 0.44 11.0 0.0 4.0 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-C2H2_aberr PF17017.5 KKK21892.1 - 0.016 15.4 0.4 2.4 8.3 0.0 2.2 2 0 0 2 2 2 0 Aberrant zinc-finger zf_UBZ PF18439.1 KKK21892.1 - 0.033 13.8 1.4 1.1 8.9 0.2 2.8 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger HNH PF01844.23 KKK21892.1 - 0.9 9.8 8.1 7.8 6.8 0.1 4.0 4 0 0 4 4 4 0 HNH endonuclease Zn-ribbon_8 PF09723.10 KKK21892.1 - 2.4 8.4 8.5 30 4.8 0.9 3.2 1 1 2 3 3 3 0 Zinc ribbon domain Zn_ribbon_recom PF13408.6 KKK21892.1 - 2.5 8.7 9.8 2 9.0 2.7 2.4 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain DUF4764 PF15961.5 KKK21892.1 - 6.3 5.3 8.2 0.3 9.7 1.2 1.9 1 1 0 2 2 2 0 Domain of unknown function (DUF4764) RRM_1 PF00076.22 KKK21893.1 - 4.3e-17 61.7 0.0 6.4e-17 61.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KKK21893.1 - 0.012 15.7 0.0 0.024 14.7 0.0 1.5 1 1 0 1 1 1 0 RNA recognition motif Limkain-b1 PF11608.8 KKK21893.1 - 0.033 14.3 0.0 0.06 13.4 0.0 1.3 1 0 0 1 1 1 0 Limkain b1 B12D PF06522.11 KKK21894.1 - 0.00042 20.1 0.1 0.00062 19.5 0.1 1.3 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit SRA1 PF07304.11 KKK21895.1 - 3.5e-09 36.6 7.6 3.5e-09 36.6 7.6 3.4 2 1 0 2 2 2 1 Steroid receptor RNA activator (SRA1) WD40 PF00400.32 KKK21895.1 - 9.2e-06 26.3 7.6 0.15 13.0 0.0 5.8 6 0 0 6 6 6 2 WD domain, G-beta repeat Sec16_C PF12931.7 KKK21895.1 - 5.7e-05 22.9 0.1 0.00075 19.2 0.1 2.2 1 1 0 1 1 1 1 Sec23-binding domain of Sec16 ANAPC4_WD40 PF12894.7 KKK21895.1 - 0.0011 19.2 0.9 0.013 15.8 0.1 3.1 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain COX6B PF02297.17 KKK21896.1 - 3e-18 65.8 6.7 3.5e-18 65.6 6.7 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb CX9C PF16860.5 KKK21896.1 - 0.013 15.5 2.2 0.021 14.8 2.2 1.3 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, APOBEC_C PF05240.14 KKK21896.1 - 0.029 14.3 0.3 0.042 13.8 0.3 1.4 1 0 0 1 1 1 0 APOBEC-like C-terminal domain ketoacyl-synt PF00109.26 KKK21896.1 - 0.095 12.3 0.0 0.095 12.3 0.0 1.1 1 0 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain ATP19 PF11022.8 KKK21901.1 - 7.7e-23 80.7 0.1 9.2e-23 80.4 0.1 1.0 1 0 0 1 1 1 1 ATP synthase subunit K COesterase PF00135.28 KKK21902.1 - 7.2e-83 279.2 0.0 3.5e-82 276.9 0.0 1.8 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KKK21902.1 - 0.00017 21.5 0.3 0.0019 18.1 0.3 2.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KKK21902.1 - 0.0027 17.2 0.0 0.0047 16.4 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family AAA PF00004.29 KKK21904.1 - 6e-38 130.3 0.0 2.2e-37 128.5 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KKK21904.1 - 1e-08 34.8 0.0 2.3e-08 33.7 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_14 PF13173.6 KKK21904.1 - 2.5e-05 24.3 0.0 6.2e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 KKK21904.1 - 2.6e-05 24.0 0.0 5.4e-05 23.0 0.0 1.5 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KKK21904.1 - 2.9e-05 24.5 0.6 0.00056 20.3 0.0 2.6 2 1 1 3 3 2 1 AAA ATPase domain AAA_5 PF07728.14 KKK21904.1 - 4.5e-05 23.5 0.1 0.00044 20.3 0.1 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 KKK21904.1 - 0.00014 22.4 0.0 0.0014 19.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_2 PF07724.14 KKK21904.1 - 0.00022 21.4 0.0 0.00048 20.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 KKK21904.1 - 0.00027 21.2 0.1 0.0065 16.7 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.6 KKK21904.1 - 0.00047 20.3 0.0 0.00095 19.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KKK21904.1 - 0.00071 19.4 0.0 0.0014 18.4 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 KKK21904.1 - 0.001 18.5 0.1 0.002 17.6 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI TniB PF05621.11 KKK21904.1 - 0.0012 18.2 0.0 1.4 8.3 0.0 2.6 2 1 1 3 3 3 2 Bacterial TniB protein RNA_helicase PF00910.22 KKK21904.1 - 0.0014 18.9 0.0 0.004 17.5 0.0 1.9 1 1 0 1 1 1 1 RNA helicase AAA_25 PF13481.6 KKK21904.1 - 0.0025 17.4 0.1 0.036 13.6 0.1 2.2 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KKK21904.1 - 0.0054 16.7 0.0 0.016 15.2 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_24 PF13479.6 KKK21904.1 - 0.0065 16.2 0.0 0.012 15.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 KKK21904.1 - 0.011 16.0 0.0 0.02 15.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.6 KKK21904.1 - 0.019 15.1 0.0 0.043 13.9 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain Rad17 PF03215.15 KKK21904.1 - 0.021 14.8 0.1 0.062 13.2 0.1 1.6 1 1 1 2 2 2 0 Rad17 P-loop domain Parvo_NS1 PF01057.17 KKK21904.1 - 0.021 13.9 0.0 0.035 13.2 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 ABC_tran PF00005.27 KKK21904.1 - 0.032 14.8 0.0 0.083 13.4 0.0 1.8 1 1 0 1 1 1 0 ABC transporter Sigma54_activat PF00158.26 KKK21904.1 - 0.035 13.8 0.0 0.074 12.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain DUF815 PF05673.13 KKK21904.1 - 0.059 12.5 0.0 0.13 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_7 PF12775.7 KKK21904.1 - 0.06 12.9 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region ATPase_2 PF01637.18 KKK21904.1 - 0.067 13.1 0.0 0.26 11.2 0.0 1.8 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea CPT PF07931.12 KKK21904.1 - 0.07 13.0 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein TsaE PF02367.17 KKK21904.1 - 0.09 12.8 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_21 PF13304.6 KKK21904.1 - 0.11 12.3 0.3 12 5.6 0.0 2.7 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system Viral_helicase1 PF01443.18 KKK21904.1 - 0.13 12.0 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase TIP49 PF06068.13 KKK21904.1 - 0.13 11.4 0.1 0.35 10.0 0.0 1.7 2 0 0 2 2 2 0 TIP49 P-loop domain Guanylate_kin PF00625.21 KKK21904.1 - 0.17 11.5 0.0 1.7 8.3 0.0 2.5 2 1 0 2 2 2 0 Guanylate kinase HIGH_NTase1_ass PF16581.5 KKK21904.1 - 0.19 11.7 0.0 1.3 8.9 0.0 2.0 2 0 0 2 2 2 0 Cytidyltransferase-related C-terminal region ACPS PF01648.20 KKK21905.1 - 1.2e-16 60.9 0.0 2.2e-16 60.0 0.0 1.5 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily PHP PF02811.19 KKK21905.1 - 2.6e-12 47.4 0.0 4e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 PHP domain 4PPT_N PF17837.1 KKK21905.1 - 0.0045 17.1 1.0 0.016 15.3 0.4 2.2 2 1 0 2 2 2 1 4'-phosphopantetheinyl transferase N-terminal domain PigN PF04987.14 KKK21906.1 - 2e-160 534.6 39.8 2e-160 534.6 39.8 2.1 2 1 0 2 2 2 1 Phosphatidylinositolglycan class N (PIG-N) Csm1 PF12539.8 KKK21906.1 - 1.2e-31 109.2 0.8 2.1e-31 108.4 0.2 1.8 2 0 0 2 2 1 1 Chromosome segregation protein Csm1/Pcs1 Phosphodiest PF01663.22 KKK21906.1 - 4.5e-09 36.4 2.4 4.3e-07 29.8 2.4 2.5 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 KKK21906.1 - 2.2e-08 33.9 0.0 3.7e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 Sulfatase MPS2 PF17060.5 KKK21906.1 - 0.062 12.6 3.8 0.11 11.8 3.8 1.3 1 0 0 1 1 1 0 Monopolar spindle protein 2 AAA_13 PF13166.6 KKK21906.1 - 0.081 11.6 4.2 0.13 10.9 4.2 1.2 1 0 0 1 1 1 0 AAA domain MscS_porin PF12795.7 KKK21906.1 - 0.12 11.9 16.8 0.24 10.9 16.8 1.4 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain DUF5094 PF17015.5 KKK21906.1 - 0.15 12.2 0.1 0.15 12.2 0.1 2.9 3 0 0 3 3 2 0 Domain of unknown function (DUF5094) Adeno_E4_34 PF04528.13 KKK21906.1 - 0.16 11.8 0.5 0.36 10.7 0.5 1.5 1 0 0 1 1 1 0 Adenovirus early E4 34 kDa protein conserved region DUF2968 PF11180.8 KKK21906.1 - 0.2 11.3 9.0 0.36 10.5 9.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) Stevor PF17410.2 KKK21906.1 - 0.21 11.1 1.2 0.5 9.9 1.2 1.6 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame APG6_N PF17675.1 KKK21906.1 - 0.21 12.1 11.0 0.46 11.0 11.0 1.6 1 0 0 1 1 1 0 Apg6 coiled-coil region TPR_MLP1_2 PF07926.12 KKK21906.1 - 0.3 11.1 11.1 1.1 9.4 11.1 2.0 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Spc7 PF08317.11 KKK21906.1 - 0.44 9.4 11.1 0.98 8.2 11.1 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein TRAF_BIRC3_bd PF16673.5 KKK21906.1 - 0.63 9.9 3.1 0.77 9.6 0.4 2.3 2 0 0 2 2 2 0 TNF receptor-associated factor BIRC3 binding domain DUF2203 PF09969.9 KKK21906.1 - 0.87 10.3 3.0 2.7 8.7 3.0 1.9 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) ADIP PF11559.8 KKK21906.1 - 1.7 8.8 12.7 2.9 8.0 11.7 1.7 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF3138 PF11336.8 KKK21906.1 - 3.8 6.0 6.7 6.8 5.2 6.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Seryl_tRNA_N PF02403.22 KKK21906.1 - 4.7 7.5 5.8 12 6.2 5.8 1.7 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Fungal_trans PF04082.18 KKK21907.1 - 4e-34 117.9 0.0 9.5e-34 116.6 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK21907.1 - 0.0016 18.5 1.0 0.0033 17.5 1.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cys_Met_Meta_PP PF01053.20 KKK21908.1 - 1.9e-143 477.6 0.0 2.2e-143 477.4 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 KKK21908.1 - 1.7e-05 24.0 0.0 3.3e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 KKK21908.1 - 0.00014 21.2 0.0 0.00021 20.6 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Met_gamma_lyase PF06838.11 KKK21908.1 - 0.00041 19.0 0.0 0.0024 16.5 0.0 1.9 1 1 0 1 1 1 1 Methionine gamma-lyase SelA PF03841.13 KKK21908.1 - 0.00075 18.6 0.0 0.0099 14.9 0.0 2.1 2 0 0 2 2 2 1 L-seryl-tRNA selenium transferase DegT_DnrJ_EryC1 PF01041.17 KKK21908.1 - 0.0034 16.7 0.1 0.013 14.8 0.0 1.9 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 KKK21908.1 - 0.025 13.8 0.0 0.088 12.1 0.0 1.7 2 0 0 2 2 2 0 Beta-eliminating lyase GDC-P PF02347.16 KKK21908.1 - 0.054 12.3 0.0 0.088 11.6 0.0 1.2 1 0 0 1 1 1 0 Glycine cleavage system P-protein SR-25 PF10500.9 KKK21909.1 - 1.1 8.8 11.0 1.6 8.3 11.0 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein IMUP PF15761.5 KKK21909.1 - 9.7 6.9 11.0 16 6.2 11.0 1.3 1 0 0 1 1 1 0 Immortalisation up-regulated protein Enolase_C PF00113.22 KKK21958.1 - 5.4e-153 508.5 0.1 7e-153 508.1 0.1 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 KKK21958.1 - 2.3e-56 189.5 0.3 4.6e-56 188.6 0.1 1.6 2 0 0 2 2 2 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 KKK21958.1 - 5.3e-05 22.9 0.0 8.6e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 KKK21958.1 - 0.025 13.7 0.1 0.83 8.8 0.1 2.5 3 0 0 3 3 3 0 Methylaspartate ammonia-lyase C-terminus 3H PF02829.14 KKK21958.1 - 0.073 13.4 0.1 0.43 10.9 0.0 2.2 2 0 0 2 2 2 0 3H domain AAA PF00004.29 KKK21959.1 - 6.5e-43 146.3 0.0 1.1e-42 145.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 KKK21959.1 - 3.9e-11 42.7 0.1 3.8e-10 39.6 0.0 2.3 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 KKK21959.1 - 1.8e-10 40.4 0.1 3.5e-10 39.5 0.1 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 KKK21959.1 - 1.1e-07 32.4 0.0 7.7e-05 23.1 0.0 2.9 2 1 1 3 3 3 1 AAA ATPase domain AAA_2 PF07724.14 KKK21959.1 - 2.3e-06 27.8 0.0 7.6e-06 26.1 0.0 1.9 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 KKK21959.1 - 2.8e-06 27.4 0.0 5.6e-05 23.2 0.0 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KKK21959.1 - 2.8e-06 27.1 0.0 6.3e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 KKK21959.1 - 0.00035 21.1 0.1 0.0029 18.2 0.0 2.4 2 1 0 2 2 2 1 AAA domain DUF815 PF05673.13 KKK21959.1 - 0.00043 19.5 0.0 0.00087 18.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 KKK21959.1 - 0.00061 20.1 0.1 0.023 15.0 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_7 PF12775.7 KKK21959.1 - 0.0023 17.5 0.0 0.0046 16.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region TsaE PF02367.17 KKK21959.1 - 0.0028 17.6 0.1 0.0092 16.0 0.0 1.8 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE TIP49 PF06068.13 KKK21959.1 - 0.003 16.8 0.1 0.0071 15.6 0.0 1.6 2 0 0 2 2 2 1 TIP49 P-loop domain Sigma54_activat PF00158.26 KKK21959.1 - 0.0048 16.6 0.0 0.014 15.1 0.0 1.9 1 1 0 1 1 1 1 Sigma-54 interaction domain IstB_IS21 PF01695.17 KKK21959.1 - 0.0052 16.5 0.0 0.01 15.6 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 KKK21959.1 - 0.0067 15.8 0.0 0.013 14.9 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 KKK21959.1 - 0.0072 16.7 0.0 0.014 15.8 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_3 PF07726.11 KKK21959.1 - 0.0097 15.8 0.1 0.032 14.1 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 KKK21959.1 - 0.015 15.3 0.0 0.032 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KKK21959.1 - 0.018 15.2 0.0 0.041 14.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KKK21959.1 - 0.03 14.0 0.0 0.075 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain GAS PF13851.6 KKK21959.1 - 0.032 13.6 0.8 0.063 12.6 0.8 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding AAA_24 PF13479.6 KKK21959.1 - 0.033 13.9 0.0 0.086 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 KKK21959.1 - 0.038 13.3 0.3 0.13 11.6 0.0 2.1 3 0 0 3 3 2 0 KaiC Prot_ATP_OB_N PF17758.1 KKK21959.1 - 0.039 13.6 0.0 0.11 12.2 0.0 1.7 1 0 0 1 1 1 0 Proteasomal ATPase OB N-terminal domain PhoH PF02562.16 KKK21959.1 - 0.046 13.2 0.0 0.083 12.3 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein Zeta_toxin PF06414.12 KKK21959.1 - 0.047 13.0 0.0 0.094 12.0 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_25 PF13481.6 KKK21959.1 - 0.049 13.2 0.1 0.11 12.0 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KKK21959.1 - 0.079 13.2 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 KKK21959.1 - 0.08 12.0 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_11 PF13086.6 KKK21959.1 - 0.087 12.6 0.1 0.27 11.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KKK21959.1 - 0.1 12.5 0.1 0.26 11.2 0.0 1.7 2 0 0 2 2 2 0 NACHT domain Thymidylate_kin PF02223.17 KKK21959.1 - 0.11 12.1 0.0 7.8 6.1 0.0 2.6 3 0 0 3 3 2 0 Thymidylate kinase DUF16 PF01519.16 KKK21959.1 - 0.14 12.7 0.7 0.38 11.3 0.7 1.7 1 0 0 1 1 1 0 Protein of unknown function DUF16 CEP209_CC5 PF16574.5 KKK21959.1 - 0.15 12.2 2.1 0.44 10.7 2.1 1.8 1 1 0 1 1 1 0 Coiled-coil region of centrosome protein CE290 DUF4482 PF14818.6 KKK21959.1 - 0.55 11.1 2.5 0.35 11.7 0.3 1.8 2 0 0 2 2 1 0 Domain of unknown function (DUF4482) Glyco_hydro_47 PF01532.20 KKK21960.1 - 5.6e-166 553.0 0.0 6.3e-166 552.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Bud13 PF09736.9 KKK21976.1 - 4.9e-50 169.7 5.5 4.9e-50 169.7 5.5 1.7 2 0 0 2 2 2 1 Pre-mRNA-splicing factor of RES complex Nop16 PF09420.10 KKK21976.1 - 0.0086 16.1 5.3 0.011 15.7 5.3 1.2 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 Cytadhesin_P30 PF07271.11 KKK21976.1 - 0.18 11.3 0.5 0.25 10.8 0.5 1.1 1 0 0 1 1 1 0 Cytadhesin P30/P32 Adap_comp_sub PF00928.21 KKK21977.1 - 6.4e-84 281.4 0.0 7.9e-84 281.1 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KKK21977.1 - 0.00024 21.0 0.1 0.00044 20.2 0.1 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.9 KKK21977.1 - 0.013 14.9 0.1 0.022 14.2 0.1 1.4 1 0 0 1 1 1 0 Muniscin C-terminal mu homology domain Myb_DNA-bind_6 PF13921.6 KKK21978.1 - 0.0002 21.5 0.1 0.00034 20.8 0.1 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KKK21978.1 - 0.01 16.0 0.2 0.02 15.0 0.2 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain Rap1_C PF11626.8 KKK21978.1 - 0.017 15.2 0.1 0.026 14.6 0.1 1.3 1 0 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain SSB PF00436.25 KKK21979.1 - 5.2e-19 68.2 0.0 6.5e-19 67.9 0.0 1.1 1 0 0 1 1 1 1 Single-strand binding protein family Erf4 PF10256.9 KKK21980.1 - 2.6e-40 137.1 0.0 4.9e-40 136.2 0.0 1.5 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family DUF4203 PF13886.6 KKK21980.1 - 1e-37 129.8 20.0 1.2e-22 80.6 1.5 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF4203) PgaD PF13994.6 KKK21980.1 - 0.08 13.0 0.1 0.3 11.1 0.1 1.9 1 0 0 1 1 1 0 PgaD-like protein STE3 PF02076.15 KKK21981.1 - 2.5e-90 302.6 11.8 3e-90 302.3 11.8 1.1 1 0 0 1 1 1 1 Pheromone A receptor Zn_clus PF00172.18 KKK21982.1 - 2.8e-08 33.7 8.8 4.9e-08 33.0 8.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KKK21982.1 - 4.3e-08 32.4 0.8 2.1e-07 30.1 0.4 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain DUF3433 PF11915.8 KKK21983.1 - 2.1e-34 117.9 15.9 3.1e-23 82.1 4.3 3.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3433) Peptidase_C14 PF00656.22 KKK21985.1 - 1.5e-20 74.2 0.0 2.1e-20 73.8 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Prp19 PF08606.11 KKK21985.1 - 0.14 12.2 0.1 0.35 10.9 0.1 1.6 1 0 0 1 1 1 0 Prp19/Pso4-like ADH_N PF08240.12 KKK21986.1 - 2.6e-30 104.5 3.0 5.5e-30 103.5 3.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KKK21986.1 - 3.2e-23 82.1 0.3 7.2e-23 81.0 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KKK21986.1 - 9.7e-10 39.6 0.0 2.1e-09 38.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KKK21986.1 - 0.0012 18.2 0.1 0.0025 17.2 0.1 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 KKK21987.1 - 9.1e-18 64.5 0.0 1.3e-15 57.4 0.0 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KKK21987.1 - 3.4e-14 52.2 0.2 3.1e-12 45.7 0.0 2.4 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KKK21987.1 - 4.2e-14 52.5 0.0 1.1e-12 47.8 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KKK21987.1 - 9.8e-09 34.8 0.0 1.1e-06 28.1 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KKK21987.1 - 2.4e-06 27.7 0.0 4e-05 23.8 0.0 3.0 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 KKK21987.1 - 2.1e-05 24.0 0.1 6.3e-05 22.4 0.1 1.8 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 KKK21987.1 - 0.00033 21.1 0.5 0.79 10.3 0.0 2.8 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KKK21987.1 - 0.0046 16.1 1.2 0.0075 15.4 1.2 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KKK21987.1 - 0.0057 15.4 0.3 0.015 14.0 0.1 1.7 2 0 0 2 2 2 1 HI0933-like protein 2-Hacid_dh_C PF02826.19 KKK21987.1 - 0.018 14.4 0.1 0.12 11.7 0.0 2.1 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GIDA PF01134.22 KKK21987.1 - 0.026 13.6 0.8 0.28 10.2 0.4 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A Shikimate_DH PF01488.20 KKK21987.1 - 0.038 14.1 0.1 13 5.9 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase AlaDh_PNT_C PF01262.21 KKK21987.1 - 0.079 12.3 0.2 0.18 11.1 0.2 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 KKK21987.1 - 0.092 12.0 0.0 1 8.5 0.0 2.2 2 0 0 2 2 2 0 Thi4 family DUF4176 PF13780.6 KKK21987.1 - 0.11 12.6 0.1 0.26 11.3 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4176) IlvN PF07991.12 KKK21987.1 - 0.14 11.7 0.2 9 5.8 0.0 2.3 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Gpr1_Fun34_YaaH PF01184.19 KKK21988.1 - 5.6e-27 94.7 14.2 7.1e-27 94.4 14.2 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family FxsA PF04186.13 KKK21988.1 - 1.1 9.5 8.1 3.4 7.8 0.2 2.4 2 1 0 2 2 2 0 FxsA cytoplasmic membrane protein Pex24p PF06398.11 KKK21988.1 - 5.3 5.9 4.4 1.1 8.1 1.2 1.5 2 0 0 2 2 2 0 Integral peroxisomal membrane peroxin Zn_clus PF00172.18 KKK21989.1 - 4.4e-08 33.1 11.3 1e-07 31.9 11.3 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain G-patch PF01585.23 KKK21990.1 - 4.7e-12 45.6 1.2 9.4e-12 44.6 1.2 1.6 1 0 0 1 1 1 1 G-patch domain RRM_1 PF00076.22 KKK21990.1 - 1.5e-08 34.3 4.0 0.00018 21.3 0.0 3.1 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) G-patch_2 PF12656.7 KKK21990.1 - 7.9e-05 22.7 1.3 0.00024 21.1 1.3 1.8 1 0 0 1 1 1 1 G-patch domain RED_N PF07808.13 KKK21990.1 - 0.17 11.4 0.0 0.17 11.4 0.0 2.8 3 0 0 3 3 3 0 RED-like protein N-terminal region Mst1_SARAH PF11629.8 KKK21991.1 - 0.066 13.3 0.1 0.14 12.3 0.1 1.5 1 0 0 1 1 1 0 C terminal SARAH domain of Mst1 Pectate_lyase_3 PF12708.7 KKK21992.1 - 5e-65 219.4 16.5 8.1e-56 189.2 1.1 3.2 3 1 1 4 4 4 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 KKK21992.1 - 0.013 15.2 0.1 0.046 13.4 0.0 2.0 2 0 0 2 2 2 0 N terminal extension of bacteriophage endosialidase BNR_4 PF15892.5 KKK22008.1 - 0.083 12.2 0.0 0.091 12.1 0.0 1.1 1 0 0 1 1 1 0 BNR repeat-containing family member Autoind_bind PF03472.15 KKK22008.1 - 0.092 12.2 0.9 7.1 6.1 0.1 2.1 2 0 0 2 2 2 0 Autoinducer binding domain GARS_A PF01071.19 KKK22009.1 - 3.1e-84 281.6 0.0 5.3e-84 280.8 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.15 KKK22009.1 - 4e-35 120.5 0.0 1.8e-34 118.4 0.0 2.2 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, N domain AIRS_C PF02769.22 KKK22009.1 - 5.5e-35 120.8 0.0 1.1e-34 119.8 0.0 1.5 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain GARS_C PF02843.16 KKK22009.1 - 2.6e-26 91.7 0.3 6.6e-26 90.4 0.3 1.8 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.24 KKK22009.1 - 2.7e-06 27.9 0.6 1.5e-05 25.6 0.6 2.2 1 1 0 1 1 1 1 AIR synthase related protein, N-terminal domain CPSase_L_D2 PF02786.17 KKK22009.1 - 3.1e-05 23.6 0.0 5.6e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_3 PF02655.14 KKK22009.1 - 4.9e-05 23.4 0.0 0.00016 21.7 0.0 1.9 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp PF02222.22 KKK22009.1 - 5.4e-05 22.8 0.0 9.5e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.6 KKK22009.1 - 0.0013 18.4 0.0 0.023 14.3 0.0 2.3 2 0 0 2 2 2 1 ATP-grasp domain RimK PF08443.11 KKK22009.1 - 0.0062 16.1 0.0 0.017 14.7 0.0 1.7 2 0 0 2 2 2 1 RimK-like ATP-grasp domain Actin PF00022.19 KKK22010.1 - 1.8e-143 478.0 0.0 7.2e-143 476.1 0.0 1.7 1 1 0 1 1 1 1 Actin SOAR PF16533.5 KKK22011.1 - 0.24 11.4 1.7 4.3 7.4 0.0 2.7 2 0 0 2 2 2 0 STIM1 Orai1-activating region Pet127 PF08634.10 KKK22012.1 - 1.5e-97 326.3 6.5 1.5e-51 175.5 0.7 2.2 1 1 1 2 2 2 2 Mitochondrial protein Pet127 DUF4247 PF14042.6 KKK22012.1 - 0.29 11.8 1.3 14 6.4 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4247) HSP9_HSP12 PF04119.12 KKK22012.1 - 0.62 10.5 3.5 38 4.8 2.0 2.8 2 0 0 2 2 2 0 Heat shock protein 9/12 Sld7_C PF18596.1 KKK22013.1 - 8.6e-14 51.4 0.0 2.5e-13 50.0 0.0 1.8 2 0 0 2 2 2 1 Sld7 C-terminal domain Vps55 PF04133.14 KKK22014.1 - 1.9e-42 143.9 6.6 2.2e-42 143.7 6.6 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 IGPD PF00475.18 KKK22015.1 - 8.4e-56 188.3 0.4 1.1e-55 187.9 0.4 1.1 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase Arena_RNA_pol PF06317.11 KKK22015.1 - 0.033 11.4 0.0 0.042 11.0 0.0 1.0 1 0 0 1 1 1 0 Arenavirus RNA polymerase Fes1 PF08609.10 KKK22017.1 - 4.9e-32 110.7 5.6 6.4e-31 107.1 3.9 2.5 3 0 0 3 3 3 1 Nucleotide exchange factor Fes1 HEAT_EZ PF13513.6 KKK22017.1 - 1.6e-07 31.7 0.1 8.3e-07 29.4 0.0 2.3 3 0 0 3 3 3 1 HEAT-like repeat HEAT PF02985.22 KKK22017.1 - 3.2e-07 30.1 0.1 0.05 13.9 0.0 2.8 2 0 0 2 2 2 2 HEAT repeat HEAT_2 PF13646.6 KKK22017.1 - 3.9e-07 30.4 0.1 2.4e-06 27.8 0.1 2.2 2 1 0 2 2 2 1 HEAT repeats Arm PF00514.23 KKK22017.1 - 1.2e-06 28.4 0.1 0.0015 18.5 0.0 2.5 2 0 0 2 2 2 2 Armadillo/beta-catenin-like repeat V-ATPase_H_N PF03224.14 KKK22017.1 - 0.055 12.7 0.0 0.062 12.6 0.0 1.1 1 0 0 1 1 1 0 V-ATPase subunit H Adaptin_N PF01602.20 KKK22017.1 - 0.078 11.5 0.1 0.18 10.3 0.1 1.5 1 1 0 1 1 1 0 Adaptin N terminal region PSD2 PF07624.11 KKK22017.1 - 0.082 12.7 0.1 0.36 10.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1585) 2-Hacid_dh_C PF02826.19 KKK22018.1 - 1.3e-50 171.2 0.0 2.9e-50 170.1 0.0 1.6 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KKK22018.1 - 6.4e-15 55.0 0.0 8.5e-15 54.6 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KKK22018.1 - 7.2e-05 23.0 0.0 0.00016 21.9 0.0 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase AlaDh_PNT_C PF01262.21 KKK22018.1 - 0.033 13.5 0.1 1.8 7.8 0.0 2.2 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain GFO_IDH_MocA PF01408.22 KKK22018.1 - 0.098 13.5 0.0 0.4 11.5 0.0 2.0 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold Shikimate_DH PF01488.20 KKK22018.1 - 0.11 12.6 0.0 0.28 11.2 0.0 1.7 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase PROCN PF08083.11 KKK22018.1 - 0.16 10.6 0.0 0.22 10.2 0.0 1.1 1 0 0 1 1 1 0 PROCN (NUC071) domain Drf_GBD PF06371.13 KKK22019.1 - 9.9e-72 240.4 0.4 2.4e-71 239.2 0.0 1.8 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 KKK22019.1 - 2.4e-54 183.9 0.2 1.6e-52 178.0 0.0 2.6 1 1 1 2 2 2 2 Diaphanous FH3 Domain Mis12 PF05859.12 KKK22019.1 - 0.3 11.2 3.4 0.78 9.8 3.4 1.7 1 0 0 1 1 1 0 Mis12 protein GTA_holin_3TM PF11351.8 KKK22019.1 - 0.37 11.3 3.0 1.3 9.6 3.0 2.0 1 0 0 1 1 1 0 Holin of 3TMs, for gene-transfer release UPF0220 PF05255.11 KKK22020.1 - 2.5e-72 241.8 2.4 2.8e-72 241.7 2.4 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) MBOAT PF03062.19 KKK22021.1 - 6.9e-50 170.3 6.3 2.3e-49 168.6 6.3 1.8 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family DUF679 PF05078.12 KKK22021.1 - 0.047 13.6 0.1 0.088 12.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF679) DUF983 PF06170.12 KKK22021.1 - 0.12 12.8 0.3 0.35 11.3 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF983) Sec1 PF00995.23 KKK22022.1 - 6.2e-133 445.0 0.1 7.4e-133 444.8 0.1 1.1 1 0 0 1 1 1 1 Sec1 family B12-binding PF02310.19 KKK22022.1 - 0.016 15.3 0.1 0.044 13.8 0.1 1.7 1 0 0 1 1 1 0 B12 binding domain Suc_Fer-like PF06999.12 KKK22023.1 - 8.8e-55 185.6 0.0 1.4e-54 184.9 0.0 1.3 1 0 0 1 1 1 1 Sucrase/ferredoxin-like tRNA-synt_1 PF00133.22 KKK22023.1 - 2.6e-54 184.5 0.0 5.5e-36 124.0 0.0 5.7 2 1 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.6 KKK22023.1 - 1.5e-40 138.7 0.0 2.5e-40 138.0 0.0 1.3 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.11 KKK22023.1 - 8.1e-28 97.3 0.3 6.5e-22 77.8 0.0 4.3 4 1 1 5 5 5 3 tRNA synthetases class I (M) CPBP PF02517.16 KKK22023.1 - 7.3e-16 58.3 6.2 2.6e-15 56.6 6.2 2.0 1 0 0 1 1 1 1 CPBP intramembrane metalloprotease Anticodon_1 PF08264.13 KKK22023.1 - 1.9e-09 37.6 0.0 3.7e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1d PF00750.19 KKK22023.1 - 0.075 12.0 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (R) tRNA-synt_1e PF01406.19 KKK22023.1 - 0.14 11.5 0.0 7.5 5.8 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain adh_short PF00106.25 KKK22025.1 - 4.6e-28 98.0 0.0 6.2e-28 97.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KKK22025.1 - 7.8e-21 74.7 0.0 1e-20 74.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KKK22025.1 - 5.6e-07 29.6 0.0 7.7e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KKK22025.1 - 0.0013 18.3 0.1 0.0049 16.4 0.0 2.0 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family Lysine_decarbox PF03641.14 KKK22026.1 - 2.9e-25 88.9 0.0 6.7e-25 87.7 0.0 1.6 1 1 0 1 1 1 1 Possible lysine decarboxylase LDcluster4 PF18306.1 KKK22026.1 - 0.012 15.2 0.4 0.16 11.5 0.0 2.3 2 0 0 2 2 2 0 SLOG cluster4 family DAGK_cat PF00781.24 KKK22026.1 - 0.68 9.6 3.0 13 5.4 0.1 3.1 2 1 1 3 3 3 0 Diacylglycerol kinase catalytic domain Proteasome PF00227.26 KKK22027.1 - 4.1e-49 166.7 0.1 5.3e-49 166.3 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KKK22027.1 - 1.3e-12 47.2 0.4 2e-12 46.5 0.4 1.3 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature APH PF01636.23 KKK22028.1 - 7.8e-17 62.0 0.0 7.4e-08 32.6 0.0 4.0 4 0 0 4 4 4 3 Phosphotransferase enzyme family DUF3684 PF12449.8 KKK22029.1 - 0 1392.9 0.0 0 1392.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3684) Chorismate_bind PF00425.18 KKK22029.1 - 1.2e-64 218.4 0.0 1.4e-63 214.9 0.0 2.2 1 1 0 1 1 1 1 chorismate binding enzyme Med6 PF04934.14 KKK22029.1 - 2.2e-36 124.6 0.0 5.2e-36 123.4 0.0 1.7 1 0 0 1 1 1 1 MED6 mediator sub complex component GATase PF00117.28 KKK22029.1 - 5.2e-26 91.6 0.0 2.3e-25 89.5 0.0 2.0 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.13 KKK22029.1 - 1e-07 32.3 0.0 3.1e-07 30.7 0.0 1.9 1 0 0 1 1 1 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.13 KKK22029.1 - 0.00072 19.4 0.3 0.003 17.4 0.1 2.2 2 0 0 2 2 2 1 Peptidase C26 HATPase_c_3 PF13589.6 KKK22029.1 - 0.0034 17.2 0.0 0.01 15.7 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase UPF0767 PF15990.5 KKK22029.1 - 0.16 12.1 1.3 0.46 10.7 1.3 1.7 1 0 0 1 1 1 0 UPF0767 family WLM PF08325.10 KKK22029.1 - 3 7.9 6.0 0.28 11.2 0.1 2.3 3 0 0 3 3 3 0 WLM domain TRAPPC9-Trs120 PF08626.11 KKK22030.1 - 0 1494.9 0.0 0 1494.7 0.0 1.0 1 0 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit MFS_1 PF07690.16 KKK22035.1 - 9.7e-47 159.6 27.4 9.7e-47 159.6 27.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KKK22035.1 - 4.9e-11 42.2 10.4 4.9e-11 42.2 10.4 2.6 2 1 0 3 3 3 2 Sugar (and other) transporter MFS_4 PF06779.14 KKK22035.1 - 2e-05 24.1 13.7 4e-05 23.1 5.3 2.9 3 0 0 3 3 3 2 Uncharacterised MFS-type transporter YbfB OATP PF03137.20 KKK22035.1 - 0.17 10.1 12.8 0.27 9.5 2.1 3.1 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family DUF2015 PF09435.10 KKK22037.1 - 1.1e-46 157.2 0.0 1.3e-46 157.0 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2015) RRM_1 PF00076.22 KKK22038.1 - 1.2e-35 121.1 0.0 8.6e-17 60.7 0.1 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KKK22038.1 - 1.2e-05 24.9 0.1 0.077 12.6 0.0 2.3 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KKK22038.1 - 0.00016 21.7 0.0 0.001 19.2 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif OB_RNB PF08206.11 KKK22038.1 - 0.0034 17.0 0.2 0.33 10.7 0.1 2.4 2 0 0 2 2 2 1 Ribonuclease B OB domain Cas_Cas2CT1978 PF09707.10 KKK22038.1 - 0.03 14.4 0.0 4.7 7.4 0.0 2.3 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Cas2CT1978) RRM_occluded PF16842.5 KKK22038.1 - 0.035 14.0 0.0 0.073 12.9 0.0 1.5 1 0 0 1 1 1 0 Occluded RNA-recognition motif Limkain-b1 PF11608.8 KKK22038.1 - 0.12 12.4 0.2 2.5 8.2 0.1 2.2 2 0 0 2 2 2 0 Limkain b1 CMV_1a_C PF12503.8 KKK22038.1 - 0.15 12.1 0.5 13 5.9 0.1 2.7 2 1 1 3 3 3 0 Cucumber mosaic virus 1a protein C terminal Ribosomal_L28e PF01778.17 KKK22039.1 - 9.2e-36 123.1 0.3 1.4e-35 122.5 0.3 1.3 1 0 0 1 1 1 1 Ribosomal L28e protein family Med3 PF11593.8 KKK22039.1 - 0.95 8.6 8.1 1.2 8.3 8.1 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal WD40 PF00400.32 KKK22040.1 - 5.7e-63 207.4 13.2 1.3e-09 38.5 0.1 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKK22040.1 - 1.9e-21 76.1 0.1 0.00012 22.3 0.0 6.7 2 2 5 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain Tup_N PF08581.10 KKK22040.1 - 5.2e-12 45.9 5.1 7.6e-12 45.4 5.1 1.2 1 0 0 1 1 1 1 Tup N-terminal WD40_like PF17005.5 KKK22040.1 - 6.7e-09 35.5 0.0 0.068 12.5 0.0 4.2 3 1 2 5 5 5 3 WD40-like domain Ge1_WD40 PF16529.5 KKK22040.1 - 1.6e-06 27.3 0.1 0.34 9.8 0.0 4.8 1 1 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 KKK22040.1 - 6.6e-06 24.9 1.0 0.00031 19.4 0.2 2.5 1 1 1 2 2 2 2 Cytochrome D1 heme domain Nup160 PF11715.8 KKK22040.1 - 1.1e-05 24.3 0.1 0.21 10.2 0.0 3.3 2 1 1 3 3 3 2 Nucleoporin Nup120/160 eIF2A PF08662.11 KKK22040.1 - 0.00027 20.9 0.0 0.052 13.4 0.0 3.0 1 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.6 KKK22040.1 - 0.016 14.6 0.0 5.6 6.2 0.0 2.9 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal zf-C2H2 PF00096.26 KKK22041.1 - 5.3e-12 45.5 42.5 0.00015 22.0 0.6 4.9 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KKK22041.1 - 3.2e-11 43.1 23.2 2.2e-07 31.0 0.7 4.9 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 KKK22041.1 - 5.2e-05 23.7 40.7 0.017 16.0 0.5 5.4 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2_8 PF15909.5 KKK22041.1 - 0.00071 19.8 6.4 0.017 15.4 3.4 3.2 1 1 2 3 3 3 1 C2H2-type zinc ribbon zf-met PF12874.7 KKK22041.1 - 0.0079 16.5 11.7 0.047 14.1 0.9 3.8 4 0 0 4 4 4 1 Zinc-finger of C2H2 type zf-LYAR PF08790.11 KKK22041.1 - 0.033 14.1 8.6 1.7 8.6 0.3 4.3 4 0 0 4 4 4 0 LYAR-type C2HC zinc finger zf-C2H2_6 PF13912.6 KKK22041.1 - 1.2 9.2 17.9 2 8.5 0.8 4.9 4 0 0 4 4 4 0 C2H2-type zinc finger zf-DNA_Pol PF08996.10 KKK22041.1 - 2.8 7.6 5.7 15 5.2 1.1 2.2 1 1 1 2 2 2 0 DNA Polymerase alpha zinc finger zf-C2H2_aberr PF17017.5 KKK22041.1 - 4.8 7.3 15.7 0.48 10.5 0.3 3.8 3 1 1 4 4 4 0 Aberrant zinc-finger Mito_carr PF00153.27 KKK22042.1 - 3.7e-48 161.4 0.1 8.8e-24 83.3 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein MFS_1 PF07690.16 KKK22058.1 - 1e-42 146.4 44.5 1e-42 146.4 44.5 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KKK22058.1 - 7.4e-09 34.6 21.3 1.1e-08 34.1 21.3 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF5337 PF17272.2 KKK22058.1 - 0.86 9.5 7.3 3.3 7.6 1.8 2.9 2 0 0 2 2 2 0 Family of unknown function (DUF5337) Orai-1 PF07856.12 KKK22058.1 - 2 8.0 6.0 0.6 9.8 0.9 2.6 3 0 0 3 3 3 0 Mediator of CRAC channel activity OATP PF03137.20 KKK22058.1 - 3.3 5.9 16.9 3.5e+02 -0.8 16.4 2.6 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Aldolase_II PF00596.21 KKK22059.1 - 1e-34 120.1 0.0 1.3e-34 119.8 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Fer2_4 PF13510.6 KKK22059.1 - 0.13 12.3 0.3 10 6.2 0.1 2.4 2 1 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain Aa_trans PF01490.18 KKK22060.1 - 5.7e-28 97.8 44.0 2.1e-14 53.1 12.9 2.0 1 1 0 2 2 2 2 Transmembrane amino acid transporter protein K1 PF02960.14 KKK22060.1 - 1.1 9.4 0.0 1.1 9.4 0.0 2.9 3 0 0 3 3 3 0 K1 glycoprotein DAO PF01266.24 KKK22061.1 - 3.3e-35 122.3 0.0 3.8e-35 122.1 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KKK22061.1 - 0.00067 18.9 0.0 0.00097 18.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KKK22061.1 - 0.0032 17.7 0.3 0.0081 16.4 0.3 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KKK22061.1 - 0.021 14.0 0.1 0.021 14.0 0.1 1.7 2 0 0 2 2 2 0 Thi4 family Pyr_redox PF00070.27 KKK22061.1 - 0.028 15.0 0.1 0.15 12.7 0.1 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KKK22061.1 - 0.036 13.3 0.0 0.058 12.6 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KKK22061.1 - 0.055 12.7 0.3 0.088 12.0 0.3 1.3 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.12 KKK22061.1 - 0.089 11.8 0.0 2.4 7.1 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein DLH PF01738.18 KKK22062.1 - 1.1e-21 77.4 0.0 1.4e-21 77.1 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family DUF915 PF06028.11 KKK22062.1 - 0.024 13.9 0.0 0.033 13.5 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Aldedh PF00171.22 KKK22063.1 - 7e-163 542.4 0.1 7.8e-163 542.2 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 KKK22063.1 - 0.034 13.6 0.1 0.4 10.1 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1487) p450 PF00067.22 KKK22064.1 - 3e-40 138.3 0.0 3.5e-40 138.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FMO-like PF00743.19 KKK22065.1 - 6.8e-16 57.8 0.0 1.9e-15 56.3 0.0 1.7 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 KKK22065.1 - 3.5e-08 33.5 0.0 9.8e-08 32.1 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KKK22065.1 - 0.00043 20.3 0.1 0.0012 18.8 0.0 1.8 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 KKK22065.1 - 0.0011 18.3 0.0 0.009 15.3 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KKK22065.1 - 0.0014 18.0 0.0 0.043 13.1 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 KKK22065.1 - 0.0056 16.1 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox PF00070.27 KKK22065.1 - 0.2 12.2 0.0 3.5 8.3 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ADH_zinc_N PF00107.26 KKK22066.1 - 6.9e-16 58.4 0.0 9.9e-16 57.9 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 KKK22066.1 - 8.4e-09 35.3 0.0 1.8e-08 34.2 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 KKK22066.1 - 1.1e-07 32.9 0.0 1.8e-07 32.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Zn_clus PF00172.18 KKK22067.1 - 2.1e-05 24.5 12.3 2.1e-05 24.5 12.3 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SUIM_assoc PF16619.5 KKK22067.1 - 1.3 9.2 5.7 4 7.6 5.7 1.8 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 p450 PF00067.22 KKK22068.1 - 1.4e-34 119.7 0.0 1.9e-34 119.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Reticulon PF02453.17 KKK22068.1 - 0.1 12.6 0.0 0.25 11.3 0.0 1.6 1 0 0 1 1 1 0 Reticulon AA_permease_2 PF13520.6 KKK22069.1 - 6.6e-30 104.3 15.5 8.1e-30 104.0 15.5 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KKK22069.1 - 1.5e-19 70.0 16.5 2e-19 69.5 16.5 1.0 1 0 0 1 1 1 1 Amino acid permease adh_short_C2 PF13561.6 KKK22070.1 - 4e-47 160.7 0.0 8.7e-47 159.6 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KKK22070.1 - 5.7e-38 130.3 0.0 8e-38 129.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KKK22070.1 - 1.8e-05 24.7 0.0 0.00013 22.0 0.0 2.0 1 1 0 1 1 1 1 KR domain Kp4 PF09044.10 KKK22070.1 - 0.011 15.8 0.0 0.026 14.6 0.0 1.6 1 0 0 1 1 1 0 Kp4 TAL_FSA PF00923.19 KKK22071.1 - 5.3e-76 255.7 0.0 6.2e-76 255.5 0.0 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase Chorismate_synt PF01264.21 KKK22071.1 - 0.13 10.9 0.0 0.2 10.3 0.0 1.2 1 0 0 1 1 1 0 Chorismate synthase Abhydrolase_3 PF07859.13 KKK22072.1 - 8.7e-43 146.6 0.0 1.2e-42 146.2 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KKK22072.1 - 1.6e-06 27.3 0.1 8.8e-06 24.8 0.1 1.9 1 1 0 1 1 1 1 Carboxylesterase family Patatin PF01734.22 KKK22072.1 - 0.16 12.2 0.1 0.3 11.2 0.0 1.5 2 0 0 2 2 2 0 Patatin-like phospholipase ADH_N PF08240.12 KKK22073.1 - 1.5e-29 102.0 1.1 8.4e-29 99.7 0.0 2.5 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KKK22073.1 - 2.6e-21 76.0 0.1 4.4e-21 75.2 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KKK22073.1 - 1.2e-06 28.2 0.1 2.3e-06 27.3 0.1 1.5 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 KKK22073.1 - 0.00012 23.1 0.1 0.00079 20.5 0.0 2.3 2 1 0 2 2 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KKK22073.1 - 0.0015 17.8 0.6 0.0023 17.3 0.6 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_2 PF07992.14 KKK22073.1 - 0.0035 16.6 0.0 0.0052 16.1 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KKK22073.1 - 0.0038 16.0 0.2 0.0054 15.5 0.2 1.2 1 0 0 1 1 1 1 HI0933-like protein AdoHcyase_NAD PF00670.21 KKK22073.1 - 0.0055 16.8 0.4 0.16 12.1 0.4 2.2 2 0 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Pyr_redox PF00070.27 KKK22073.1 - 0.0084 16.7 0.0 0.045 14.3 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 KKK22073.1 - 0.16 11.3 0.0 0.28 10.5 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.6 KKK22073.1 - 0.17 11.1 0.1 0.3 10.3 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Aldo_ket_red PF00248.21 KKK22074.1 - 4.5e-45 154.1 0.1 4.2e-43 147.6 0.1 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Cupin_3 PF05899.12 KKK22075.1 - 0.00093 18.8 0.0 0.0015 18.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_6 PF12852.7 KKK22075.1 - 0.0033 17.2 0.0 0.0042 16.8 0.0 1.2 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.11 KKK22075.1 - 0.013 15.2 0.0 0.022 14.5 0.0 1.3 1 0 0 1 1 1 0 Cupin domain SprB PF13573.6 KKK22075.1 - 0.026 14.3 0.1 0.064 13.0 0.1 1.6 1 0 0 1 1 1 0 SprB repeat AA_permease_2 PF13520.6 KKK22076.1 - 5.5e-36 124.3 32.5 9.4e-35 120.2 32.5 1.9 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KKK22076.1 - 3.7e-12 45.6 25.7 3.7e-12 45.6 25.7 2.0 1 1 1 2 2 2 1 Amino acid permease 4HBT_3 PF13622.6 KKK22077.1 - 1e-31 111.1 0.2 2.2e-31 110.0 0.2 1.5 1 1 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 KKK22077.1 - 0.00013 21.9 0.2 0.68 9.8 0.0 3.8 2 2 1 3 3 3 2 Acyl-CoA thioesterase PD40 PF07676.12 KKK22077.1 - 0.074 13.0 0.1 0.29 11.1 0.1 2.0 1 0 0 1 1 1 0 WD40-like Beta Propeller Repeat ANAPC4_WD40 PF12894.7 KKK22077.1 - 0.086 13.1 0.0 0.21 11.9 0.0 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain Ribosomal_S6 PF01250.17 KKK22078.1 - 8e-23 80.5 0.0 1e-22 80.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S6 NmrA PF05368.13 KKK22079.1 - 1.1e-33 116.8 0.0 1.4e-33 116.4 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KKK22079.1 - 2.8e-12 46.9 0.0 4e-12 46.4 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KKK22079.1 - 8.2e-06 25.4 0.0 0.0029 17.1 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 KKK22079.1 - 0.029 13.5 0.0 0.12 11.5 0.0 1.8 2 0 0 2 2 2 0 Male sterility protein GDP_Man_Dehyd PF16363.5 KKK22079.1 - 0.036 13.5 0.0 0.05 13.0 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase KR PF08659.10 KKK22079.1 - 0.11 12.4 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 KR domain Polysacc_synt_2 PF02719.15 KKK22079.1 - 0.12 11.5 0.0 17 4.4 0.0 2.5 3 0 0 3 3 3 0 Polysaccharide biosynthesis protein Chs7 PF12271.8 KKK22081.1 - 3.6e-125 417.1 15.5 4.1e-125 416.9 15.5 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone DUF3382 PF11862.8 KKK22081.1 - 0.014 15.6 1.6 0.014 15.6 1.6 2.8 1 1 2 3 3 3 0 Domain of unknown function (DUF3382) Hydrolase_4 PF12146.8 KKK22082.1 - 0.00084 18.7 0.0 0.0014 18.0 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 KKK22082.1 - 0.00087 19.1 0.0 0.0017 18.1 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_3 PF07859.13 KKK22082.1 - 0.005 16.7 0.0 0.0087 15.9 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF676 PF05057.14 KKK22082.1 - 0.022 14.3 0.0 0.058 12.9 0.0 1.7 1 1 0 1 1 1 0 Putative serine esterase (DUF676) LCAT PF02450.15 KKK22082.1 - 0.042 13.0 0.0 0.062 12.5 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Abhydrolase_6 PF12697.7 KKK22082.1 - 0.07 13.7 6.4 0.16 12.5 6.5 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 KKK22082.1 - 0.21 11.4 0.3 0.44 10.3 0.0 1.6 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Tom5 PF10642.9 KKK22083.1 - 1.2e-22 79.6 0.1 1.3e-22 79.5 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit or translocase Med26 PF08711.11 KKK22084.1 - 6.2e-12 45.3 0.0 1.3e-11 44.4 0.0 1.6 1 0 0 1 1 1 1 TFIIS helical bundle-like domain HIG_1_N PF04588.13 KKK22085.1 - 3.2e-06 27.3 1.8 3.2e-06 27.3 1.8 1.7 2 0 0 2 2 2 1 Hypoxia induced protein conserved region Troponin-I_N PF11636.8 KKK22085.1 - 0.043 13.8 0.3 0.091 12.7 0.3 1.5 1 0 0 1 1 1 0 Troponin I residues 1-32 PTR2 PF00854.21 KKK22086.1 - 3.3e-78 263.3 8.9 5e-78 262.7 8.9 1.2 1 0 0 1 1 1 1 POT family MFS_1 PF07690.16 KKK22086.1 - 8.5e-05 21.6 23.4 8.5e-05 21.6 23.4 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily Cyclase PF04199.13 KKK22087.1 - 3.5e-09 37.0 0.0 3.7e-08 33.7 0.0 2.0 1 1 1 2 2 2 1 Putative cyclase DUF5490 PF17593.2 KKK22087.1 - 0.0017 18.3 0.2 0.0044 17.0 0.2 1.6 1 0 0 1 1 1 1 Family of unknown function (DUF5490) Cupin_3 PF05899.12 KKK22087.1 - 0.0059 16.3 0.0 0.01 15.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF861) RHD3 PF05879.12 KKK22088.1 - 0 1082.3 0.0 0 1082.0 0.0 1.0 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.19 KKK22088.1 - 6.9e-08 32.1 0.2 1.2e-07 31.3 0.2 1.2 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain Dynamin_N PF00350.23 KKK22088.1 - 8e-06 26.0 0.0 1.6e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 KKK22088.1 - 0.00011 22.2 0.0 0.0003 20.8 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_28 PF13521.6 KKK22088.1 - 0.0014 18.9 0.7 0.0033 17.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain Septin PF00735.18 KKK22088.1 - 0.16 11.2 0.0 0.29 10.4 0.0 1.4 1 0 0 1 1 1 0 Septin 4HBT_2 PF13279.6 KKK22089.1 - 1.9e-08 34.8 0.0 3.1e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily Nup54 PF13874.6 KKK22090.1 - 4.8e-41 140.1 1.6 7.2e-41 139.6 0.0 2.0 2 0 0 2 2 2 1 Nucleoporin complex subunit 54 Nup54_57_C PF18570.1 KKK22090.1 - 1.8e-11 43.4 2.6 3.3e-11 42.5 2.6 1.5 1 0 0 1 1 1 1 NUP57/Nup54 C-terminal domain Nucleoporin_FG PF13634.6 KKK22090.1 - 7e-05 23.6 90.3 0.0037 18.1 46.5 3.7 1 1 2 3 3 3 2 Nucleoporin FG repeat region Fib_alpha PF08702.10 KKK22090.1 - 0.00027 21.1 0.5 0.00062 20.0 0.5 1.5 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family DUF4200 PF13863.6 KKK22090.1 - 8.2 6.9 8.8 6.4e+02 0.7 8.8 2.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) IF3_C PF00707.22 KKK22091.1 - 2.7e-09 36.9 1.3 4.4e-09 36.2 1.3 1.4 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain IF3_N PF05198.16 KKK22091.1 - 3.2e-08 33.7 0.1 1.6e-07 31.5 0.0 2.1 2 0 0 2 2 2 1 Translation initiation factor IF-3, N-terminal domain mIF3 PF14877.6 KKK22091.1 - 1.1e-06 28.5 1.6 6.8e-06 25.9 0.5 2.5 1 1 2 3 3 3 1 Mitochondrial translation initiation factor GTP_EFTU PF00009.27 KKK22092.1 - 4.7e-57 192.7 0.1 6.7e-57 192.2 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 KKK22092.1 - 4.2e-19 68.9 0.0 9.6e-19 67.7 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 KKK22092.1 - 4.3e-17 62.3 2.1 9.9e-17 61.1 2.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KKK22092.1 - 1.3e-05 25.2 0.1 2.4e-05 24.4 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KKK22092.1 - 0.0013 18.6 0.2 0.008 16.1 0.0 2.0 1 1 1 2 2 2 1 RsgA GTPase cobW PF02492.19 KKK22092.1 - 0.008 15.8 0.5 0.17 11.5 0.0 2.1 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.9 KKK22092.1 - 0.095 12.4 0.5 8.3 6.1 0.1 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF4598 PF15370.6 KKK22093.1 - 1.2e-28 99.8 6.6 1.2e-28 99.8 6.6 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF4598) GDA1_CD39 PF01150.17 KKK22094.1 - 5.1e-97 325.2 0.0 6.7e-97 324.8 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family COMPASS-Shg1 PF05205.12 KKK22095.1 - 2.8e-25 89.0 0.2 6.3e-25 87.8 0.2 1.6 1 0 0 1 1 1 1 COMPASS (Complex proteins associated with Set1p) component shg1 IF4E PF01652.18 KKK22096.1 - 4.6e-32 111.0 0.2 6.5e-32 110.5 0.2 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Cation_efflux PF01545.21 KKK22097.1 - 1.5e-13 50.9 12.1 2.1e-13 50.5 12.1 1.1 1 0 0 1 1 1 1 Cation efflux family GCV_H PF01597.19 KKK22099.1 - 6.4e-37 126.2 0.5 7.6e-37 125.9 0.5 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein Biotin_lipoyl PF00364.22 KKK22099.1 - 0.11 12.3 0.3 0.3 10.9 0.1 1.7 1 1 0 1 1 1 0 Biotin-requiring enzyme zf-rbx1 PF12678.7 KKK22100.1 - 2.2e-08 34.3 2.4 5.6e-08 33.0 2.4 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 KKK22100.1 - 6.2e-08 32.9 8.1 1.2e-07 32.0 3.5 2.5 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 KKK22100.1 - 6.3e-07 29.2 0.6 1.1e-06 28.4 0.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KKK22100.1 - 2.6e-06 27.1 2.3 2.6e-06 27.1 2.3 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KKK22100.1 - 3.3e-06 26.9 2.8 9.5e-06 25.5 2.9 1.8 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KKK22100.1 - 3.8e-05 23.5 1.4 3.8e-05 23.5 1.4 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KKK22100.1 - 4.9e-05 23.1 0.6 4.9e-05 23.1 0.6 1.8 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 KKK22100.1 - 0.00064 19.7 6.0 0.0018 18.3 1.8 3.3 1 1 1 2 2 2 1 RING-type zinc-finger Zn_ribbon_17 PF17120.5 KKK22100.1 - 0.00097 18.7 1.6 0.004 16.7 0.6 2.2 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.5 KKK22100.1 - 0.0022 17.7 12.5 0.0056 16.4 0.8 3.6 4 0 0 4 4 4 2 RING-like zinc finger zf-ANAPC11 PF12861.7 KKK22100.1 - 0.0081 16.2 1.2 0.019 15.0 1.2 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger DUF2921 PF11145.8 KKK22100.1 - 0.04 11.8 0.9 0.063 11.1 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2921) PQ-loop PF04193.14 KKK22100.1 - 0.23 11.3 5.0 4.4 7.2 0.3 2.9 2 0 0 2 2 2 0 PQ loop repeat FANCL_C PF11793.8 KKK22100.1 - 2.7 8.3 5.6 12 6.1 5.6 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain DUF3671 PF12420.8 KKK22100.1 - 4.5 7.4 4.6 36 4.5 4.6 2.2 1 1 0 1 1 1 0 Protein of unknown function DUF3099 PF11298.8 KKK22100.1 - 6.7 6.9 8.5 0.73 10.0 0.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3099) eIF3m_C_helix PF18005.1 KKK22104.1 - 1.1e-10 41.0 3.9 2.1e-10 40.1 3.9 1.5 1 0 0 1 1 1 1 eIF3 subunit M, C-terminal helix PCI PF01399.27 KKK22104.1 - 9.9e-07 29.2 0.0 1.6e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 PCI domain ADK PF00406.22 KKK22105.1 - 1.6e-40 138.7 0.0 1.1e-38 132.7 0.0 2.0 1 1 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 KKK22105.1 - 1.3e-31 109.8 0.2 4.2e-31 108.2 0.2 1.7 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KKK22105.1 - 4.9e-09 36.8 0.0 6.5e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KKK22105.1 - 8.1e-06 26.1 0.1 0.00031 20.9 0.1 2.3 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 KKK22105.1 - 1.6e-05 24.7 0.1 6.7e-05 22.6 0.1 1.9 1 1 0 1 1 1 1 Thymidylate kinase Utp8 PF10395.9 KKK22107.1 - 0.23 9.9 0.0 0.3 9.5 0.0 1.1 1 0 0 1 1 1 0 Utp8 family OmdA PF13376.6 KKK22110.1 - 1.8e-14 53.5 0.2 3.3e-14 52.6 0.2 1.5 1 0 0 1 1 1 1 Bacteriocin-protection, YdeI or OmpD-Associated Unstab_antitox PF09720.10 KKK22110.1 - 0.031 14.3 0.1 0.28 11.3 0.0 2.2 2 0 0 2 2 2 0 Putative addiction module component Fungal_trans_2 PF11951.8 KKK22111.1 - 0.0013 17.6 0.4 0.012 14.4 0.4 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain Isochorismatase PF00857.20 KKK22112.1 - 9.3e-17 61.8 0.0 1.9e-16 60.7 0.0 1.5 1 1 0 1 1 1 1 Isochorismatase family AA_permease_2 PF13520.6 KKK22117.1 - 6.9e-69 232.7 47.1 8.2e-69 232.5 47.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KKK22117.1 - 9.5e-19 67.3 37.6 1.3e-18 66.9 37.6 1.2 1 0 0 1 1 1 1 Amino acid permease DUF2304 PF10066.9 KKK22117.1 - 6.1 7.1 16.7 0.2 11.9 0.5 3.2 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2304) QCR10 PF09796.9 KKK22118.1 - 1.9e-26 91.9 0.5 2.5e-26 91.5 0.5 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) Coatomer_WDAD PF04053.14 KKK22119.1 - 2.7e-170 567.2 0.0 7.6e-170 565.7 0.0 1.7 2 0 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.32 KKK22119.1 - 1.2e-38 130.4 5.4 2.3e-06 28.2 0.0 8.3 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKK22119.1 - 1.2e-07 31.9 0.0 2.4 8.5 0.0 6.0 3 2 2 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KKK22119.1 - 0.00024 19.9 1.9 0.22 10.1 0.0 4.1 1 1 4 5 5 5 2 Nucleoporin Nup120/160 BBS2_Mid PF14783.6 KKK22119.1 - 0.07 13.2 0.0 11 6.1 0.0 3.4 2 2 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region MetallophosC PF16370.5 KKK22119.1 - 0.085 13.1 0.0 0.31 11.3 0.0 1.8 1 1 0 1 1 1 0 C terminal of Calcineurin-like phosphoesterase Thioredoxin PF00085.20 KKK22120.1 - 4e-47 158.5 0.1 1.8e-24 85.7 0.0 4.4 3 1 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.6 KKK22120.1 - 1.8e-09 37.8 0.0 0.046 13.6 0.0 5.0 3 1 2 5 5 5 2 Thioredoxin-like domain Thioredoxin_2 PF13098.6 KKK22120.1 - 2.5e-07 31.1 0.7 0.1 13.0 0.0 3.9 3 1 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KKK22120.1 - 0.00013 22.3 0.1 0.21 12.0 0.0 4.0 3 2 0 3 3 3 1 Thioredoxin-like AhpC-TSA PF00578.21 KKK22120.1 - 0.0031 17.4 1.2 0.071 13.0 0.1 3.0 3 0 0 3 3 3 1 AhpC/TSA family TraF PF13728.6 KKK22120.1 - 0.0045 16.8 4.8 0.076 12.8 0.2 3.6 3 1 1 4 4 4 1 F plasmid transfer operon protein HyaE PF07449.11 KKK22120.1 - 0.0054 16.7 0.0 2.2 8.3 0.0 3.2 4 0 0 4 4 4 1 Hydrogenase-1 expression protein HyaE Thioredoxin_7 PF13899.6 KKK22120.1 - 0.013 15.7 1.0 0.13 12.5 0.1 2.8 2 0 0 2 2 2 0 Thioredoxin-like Thioredoxin_3 PF13192.6 KKK22120.1 - 0.014 15.5 0.2 1.5 8.9 0.0 2.8 3 0 0 3 3 3 0 Thioredoxin domain OST3_OST6 PF04756.13 KKK22120.1 - 0.049 13.0 0.1 10 5.4 0.0 2.4 2 0 0 2 2 2 0 OST3 / OST6 family, transporter family DUF3557 PF12078.8 KKK22120.1 - 0.14 12.1 0.0 0.31 11.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3557) ETC_C1_NDUFA5 PF04716.14 KKK22121.1 - 7.6e-28 96.1 9.7 7.1e-27 93.0 0.0 3.1 4 0 0 4 4 4 2 ETC complex I subunit conserved region Cullin PF00888.22 KKK22140.1 - 5.9e-202 672.6 13.3 7.6e-202 672.2 13.3 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 KKK22140.1 - 2.2e-25 88.4 0.9 8.1e-25 86.6 0.9 2.1 1 0 0 1 1 1 1 Cullin protein neddylation domain Corona_S2 PF01601.16 KKK22141.1 - 0.17 10.3 10.0 0.23 9.9 10.0 1.0 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein CwfJ_C_1 PF04677.15 KKK22142.1 - 1.5e-24 86.2 0.0 2.5e-24 85.5 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.14 KKK22142.1 - 1.8e-13 51.2 0.1 3.4e-13 50.3 0.1 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 DRIM PF07539.12 KKK22143.1 - 8.7e-197 655.2 0.5 8.7e-197 655.2 0.5 2.4 3 0 0 3 3 3 1 Down-regulated in metastasis HEAT PF02985.22 KKK22143.1 - 0.00055 20.0 4.0 2.2 8.8 0.0 7.1 8 0 0 8 8 8 1 HEAT repeat DUF4556 PF15094.6 KKK22143.1 - 0.14 11.4 0.3 0.3 10.3 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4556) RRM_1 PF00076.22 KKK22145.1 - 2.3e-26 91.4 0.3 2.4e-12 46.5 0.2 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KKK22145.1 - 1.7e-05 24.4 0.0 0.00066 19.3 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KKK22145.1 - 4e-05 23.4 0.0 0.28 11.1 0.1 2.2 2 0 0 2 2 2 2 Occluded RNA-recognition motif PHM7_cyt PF14703.6 KKK22145.1 - 0.0035 17.6 1.7 0.23 11.7 0.0 3.2 3 1 1 4 4 4 1 Cytosolic domain of 10TM putative phosphate transporter RRM_8 PF11835.8 KKK22145.1 - 0.036 14.3 0.0 0.094 12.9 0.0 1.6 2 0 0 2 2 2 0 RRM-like domain ATP-synt_D PF01813.17 KKK22146.1 - 2.6e-71 239.5 1.2 3.5e-71 239.1 1.2 1.2 1 0 0 1 1 1 1 ATP synthase subunit D HtrL_YibB PF09612.10 KKK22146.1 - 0.045 13.3 0.1 0.065 12.7 0.1 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (HtrL_YibB) DUF3919 PF13057.6 KKK22146.1 - 0.095 12.3 0.6 0.14 11.8 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3919) CobA_CobO_BtuR PF02572.15 KKK22146.1 - 0.27 11.5 3.5 0.99 9.6 0.1 2.4 2 1 1 3 3 3 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP DUF5446 PF17522.2 KKK22146.1 - 0.47 10.6 2.4 0.85 9.8 0.7 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5446) TPR_14 PF13428.6 KKK22147.1 - 6.6e-12 45.2 19.7 0.78 10.7 0.0 11.7 8 3 5 13 13 13 3 Tetratricopeptide repeat Suf PF05843.14 KKK22147.1 - 6.7e-11 42.7 15.7 0.063 13.2 0.1 6.6 2 2 3 6 6 6 5 Suppressor of forked protein (Suf) TPR_19 PF14559.6 KKK22147.1 - 5e-08 33.4 0.4 2.2 8.9 0.0 5.8 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_15 PF13429.6 KKK22147.1 - 1.3e-07 31.1 7.0 0.00051 19.3 0.2 4.9 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 KKK22147.1 - 1.4e-07 31.2 6.3 0.26 11.6 0.0 7.7 7 1 1 8 8 8 1 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 KKK22147.1 - 1.4e-06 28.3 18.7 0.8 9.7 0.1 7.6 6 2 1 7 7 7 2 Mad3/BUB1 homology region 1 TPR_2 PF07719.17 KKK22147.1 - 5.6e-06 26.1 12.7 0.97 9.7 0.0 7.4 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_12 PF13424.6 KKK22147.1 - 8.8e-06 25.9 6.1 3.4 8.0 0.1 6.9 6 1 0 6 6 6 1 Tetratricopeptide repeat SNAP PF14938.6 KKK22147.1 - 0.0028 17.1 4.5 0.55 9.6 0.4 4.7 5 1 0 5 5 5 1 Soluble NSF attachment protein, SNAP TPR_17 PF13431.6 KKK22147.1 - 0.0055 17.0 4.5 1.6 9.3 0.1 6.2 6 0 0 6 6 6 1 Tetratricopeptide repeat HAT PF02184.16 KKK22147.1 - 0.014 15.4 1.9 2.8 8.0 0.0 5.3 5 0 0 5 5 4 0 HAT (Half-A-TPR) repeat RPN7 PF10602.9 KKK22147.1 - 0.022 14.5 0.3 0.62 9.7 0.1 3.0 3 1 0 3 3 3 0 26S proteasome subunit RPN7 NRDE-2 PF08424.10 KKK22147.1 - 0.051 12.7 19.8 0.049 12.8 0.3 6.5 2 2 3 5 5 5 0 NRDE-2, necessary for RNA interference TPR_1 PF00515.28 KKK22147.1 - 0.097 12.5 0.2 40 4.2 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 KKK22147.1 - 0.81 9.7 8.5 43 4.1 0.3 6.2 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_6 PF13174.6 KKK22147.1 - 7.7 7.4 14.7 20 6.1 0.0 6.8 9 0 0 9 9 6 0 Tetratricopeptide repeat PfkB PF00294.24 KKK22152.1 - 1.8e-14 53.7 0.1 2.7e-14 53.2 0.1 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase ACP PF06857.11 KKK22152.1 - 0.1 12.9 0.3 0.34 11.2 0.0 2.0 2 0 0 2 2 2 0 Malonate decarboxylase delta subunit (MdcD) DEAD PF00270.29 KKK22153.1 - 1.1e-41 142.6 0.2 1.9e-41 141.8 0.2 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KKK22153.1 - 1.3e-33 115.7 0.1 5.2e-33 113.7 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_30 PF13604.6 KKK22153.1 - 0.0015 18.3 0.0 0.0023 17.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KKK22153.1 - 0.0016 18.8 0.1 0.016 15.6 0.1 2.2 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 KKK22153.1 - 0.0042 17.1 0.0 0.0082 16.2 0.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.14 KKK22153.1 - 0.028 14.4 0.4 0.11 12.4 0.0 2.1 2 0 0 2 2 2 0 Flavivirus DEAD domain TniB PF05621.11 KKK22153.1 - 0.064 12.7 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein Helicase_RecD PF05127.14 KKK22153.1 - 0.1 12.4 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Helicase AAA_22 PF13401.6 KKK22153.1 - 0.18 12.1 1.0 0.82 9.9 1.0 2.0 1 1 0 1 1 1 0 AAA domain Aminotran_5 PF00266.19 KKK22154.1 - 5.4e-17 61.8 0.0 7.1e-12 45.0 0.0 2.3 2 0 0 2 2 2 2 Aminotransferase class-V MOSC_N PF03476.16 KKK22154.1 - 3.6e-06 26.8 0.0 8.1e-06 25.7 0.0 1.6 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain NMT1 PF09084.11 KKK22155.1 - 1.6e-79 266.8 0.0 2.1e-79 266.5 0.0 1.1 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.6 KKK22155.1 - 1.4e-05 25.0 0.2 0.087 12.5 0.0 3.2 3 1 0 3 3 3 2 NMT1-like family Glycogen_syn PF05693.13 KKK22156.1 - 0 1151.5 0.0 0 1151.3 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glyco_trans_4_4 PF13579.6 KKK22156.1 - 1e-05 26.1 0.1 2.1e-05 25.0 0.1 1.6 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.6 KKK22156.1 - 1.1e-05 25.4 0.5 2.4e-05 24.4 0.5 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 KKK22156.1 - 0.00021 21.7 0.0 0.022 15.2 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 KKK22156.1 - 0.00024 20.7 0.0 0.0031 17.1 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferases group 1 SnoaL PF07366.12 KKK22157.1 - 0.088 12.6 0.0 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 SnoaL-like polyketide cyclase KH_5 PF13184.6 KKK22157.1 - 0.13 12.4 0.7 0.23 11.6 0.7 1.3 1 0 0 1 1 1 0 NusA-like KH domain ANAPC8 PF04049.13 KKK22158.1 - 8.7e-45 152.2 1.7 9.7e-45 152.1 0.0 2.0 2 0 0 2 2 1 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_1 PF00515.28 KKK22158.1 - 5.4e-24 83.0 3.1 0.00018 21.2 0.0 7.8 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_8 PF13181.6 KKK22158.1 - 1.2e-20 71.9 16.7 1.8e-05 24.6 0.0 9.7 10 0 0 10 10 9 4 Tetratricopeptide repeat TPR_2 PF07719.17 KKK22158.1 - 1e-17 62.8 18.1 0.061 13.5 2.8 9.5 10 0 0 10 10 9 5 Tetratricopeptide repeat TPR_11 PF13414.6 KKK22158.1 - 1.2e-11 44.1 1.3 1.1e-06 28.2 0.3 4.7 2 2 2 4 4 4 2 TPR repeat TPR_9 PF13371.6 KKK22158.1 - 2.5e-10 40.3 2.4 0.0013 18.9 0.1 5.5 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 KKK22158.1 - 1.1e-09 38.2 19.4 0.007 17.1 0.0 9.4 8 2 2 10 10 10 2 Tetratricopeptide repeat TPR_19 PF14559.6 KKK22158.1 - 1.9e-09 37.9 12.0 0.13 12.8 0.0 7.7 7 1 0 7 7 7 3 Tetratricopeptide repeat TPR_17 PF13431.6 KKK22158.1 - 5.4e-08 32.7 1.4 6.2 7.5 0.0 7.2 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_16 PF13432.6 KKK22158.1 - 5.8e-08 33.2 12.6 1.7e-05 25.4 0.0 6.5 7 0 0 7 7 7 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KKK22158.1 - 6.6e-08 32.7 18.6 0.13 12.5 0.2 6.5 6 1 1 7 7 7 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 KKK22158.1 - 6.3e-06 26.4 12.0 1.9 8.8 0.0 6.8 6 2 1 7 7 7 1 Tetratricopeptide repeat TPR_15 PF13429.6 KKK22158.1 - 0.00022 20.5 7.9 0.00085 18.6 2.3 4.0 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 KKK22158.1 - 0.0037 17.2 10.8 2.9 8.1 0.0 6.5 7 0 0 7 7 6 1 Tetratricopeptide repeat RPN7 PF10602.9 KKK22158.1 - 0.072 12.8 1.2 1.4 8.6 0.1 2.9 3 0 0 3 3 3 0 26S proteasome subunit RPN7 TPR_6 PF13174.6 KKK22158.1 - 0.16 12.7 26.9 36 5.3 0.1 9.4 11 0 0 11 11 9 0 Tetratricopeptide repeat PPR PF01535.20 KKK22158.1 - 0.24 11.7 0.5 27 5.3 0.0 3.9 4 0 0 4 4 4 0 PPR repeat Sel1 PF08238.12 KKK22158.1 - 3.8 8.3 6.6 49 4.8 0.9 4.0 4 0 0 4 4 3 0 Sel1 repeat DNA_ligase_A_M PF01068.21 KKK22159.1 - 4.4e-22 78.7 0.0 7.2e-22 78.0 0.0 1.3 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 KKK22159.1 - 5.9e-18 65.8 0.0 1e-17 65.0 0.0 1.4 1 0 0 1 1 1 1 DNA ligase N terminus polyprenyl_synt PF00348.17 KKK22160.1 - 4.8e-89 297.8 0.0 5.7e-89 297.5 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase RNase_H2-Ydr279 PF09468.10 KKK22160.1 - 0.00039 20.7 0.0 0.0011 19.2 0.0 1.7 2 0 0 2 2 2 1 Ydr279p protein family (RNase H2 complex component) wHTH domain Arylsulfotran_2 PF14269.6 KKK22161.1 - 4e-62 210.3 5.7 6e-62 209.7 5.7 1.3 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 KKK22161.1 - 4.4e-17 62.1 4.2 1.3e-16 60.5 4.2 1.6 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) Vps54 PF07928.12 KKK22162.1 - 1.4e-49 168.0 1.7 1.6e-49 167.8 0.2 2.0 2 0 0 2 2 2 1 Vps54-like protein Vps54_N PF10475.9 KKK22162.1 - 1.5e-07 31.0 0.4 4e-07 29.6 0.4 1.7 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex LUC7 PF03194.15 KKK22162.1 - 0.16 11.6 0.2 0.41 10.3 0.2 1.7 1 0 0 1 1 1 0 LUC7 N_terminus DUF4363 PF14276.6 KKK22162.1 - 1.2 9.3 3.3 29 4.8 0.1 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4363) MCM PF00493.23 KKK22163.1 - 3.5e-103 343.5 0.1 7.4e-103 342.5 0.0 1.5 2 0 0 2 2 2 1 MCM P-loop domain MCM_OB PF17207.3 KKK22163.1 - 6.3e-37 126.2 0.3 1.2e-36 125.4 0.3 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KKK22163.1 - 1.2e-28 99.3 1.6 3e-28 98.1 1.6 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KKK22163.1 - 4.2e-15 56.2 0.0 1e-14 55.0 0.0 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 KKK22163.1 - 5.6e-06 25.9 0.0 0.00074 19.0 0.0 2.3 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KKK22163.1 - 4.5e-05 23.5 0.0 0.00011 22.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 KKK22163.1 - 0.00095 19.0 0.0 0.0036 17.2 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KKK22163.1 - 0.081 12.6 0.0 1.2 8.9 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain Imm35 PF15567.6 KKK22163.1 - 0.1 12.8 0.0 0.23 11.7 0.0 1.5 1 0 0 1 1 1 0 Immunity protein 35 DUF3449 PF11931.8 KKK22164.1 - 1e-74 250.4 1.6 1.3e-74 250.0 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3449) SF3A3 PF16837.5 KKK22164.1 - 1.8e-25 89.3 1.3 1.8e-25 89.3 1.3 2.0 2 0 0 2 2 2 1 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 SF3a60_bindingd PF12108.8 KKK22164.1 - 2e-14 53.2 0.9 4.8e-14 51.9 0.9 1.7 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain zf-met PF12874.7 KKK22164.1 - 4e-09 36.6 2.9 1.2e-07 31.9 1.3 2.4 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KKK22164.1 - 1e-08 35.2 1.5 1e-08 35.2 1.5 2.5 2 1 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KKK22164.1 - 0.0012 19.2 0.0 0.009 16.3 0.0 2.4 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-C4H2 PF10146.9 KKK22164.1 - 0.015 15.6 0.9 0.015 15.6 0.9 2.0 2 0 0 2 2 2 0 Zinc finger-containing protein zf-LYAR PF08790.11 KKK22164.1 - 0.084 12.8 0.2 0.21 11.5 0.2 1.7 1 0 0 1 1 1 0 LYAR-type C2HC zinc finger PRP9_N PF16958.5 KKK22164.1 - 0.19 11.7 23.6 0.03 14.4 3.0 3.6 4 1 1 5 5 5 0 Pre-mRNA-splicing factor PRP9 N-terminus zf-C2H2_4 PF13894.6 KKK22164.1 - 0.63 11.0 4.0 10 7.2 0.1 2.8 3 0 0 3 3 2 0 C2H2-type zinc finger zf-C2H2 PF00096.26 KKK22164.1 - 1.2 9.7 3.7 5.1 7.8 0.4 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type DUF913 PF06025.12 KKK22167.1 - 2.8e-133 444.5 12.9 4.2e-132 440.6 0.0 5.2 5 0 0 5 5 5 2 Domain of Unknown Function (DUF913) DUF908 PF06012.12 KKK22167.1 - 5.2e-115 384.7 1.1 5.2e-115 384.7 1.1 2.6 3 0 0 3 3 3 1 Domain of Unknown Function (DUF908) HECT PF00632.25 KKK22167.1 - 5.7e-93 311.8 0.0 9.7e-93 311.0 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) UBM PF14377.6 KKK22167.1 - 1.5e-30 103.6 21.8 1.9e-10 39.8 1.8 4.6 3 0 0 3 3 3 3 Ubiquitin binding region NARP1 PF12569.8 KKK22167.1 - 0.29 10.0 6.1 0.64 8.9 6.1 1.5 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 AP-5_subunit_s1 PF15001.6 KKK22167.1 - 3.1 7.7 6.1 3.3 7.7 4.0 2.2 2 0 0 2 2 2 0 AP-5 complex subunit sigma-1 Pribosyltran_N PF13793.6 KKK22168.1 - 4.7e-46 155.5 1.5 1.5e-44 150.7 0.1 2.5 3 0 0 3 3 3 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 KKK22168.1 - 1.4e-41 142.5 2.4 6.3e-35 120.9 1.2 2.5 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 KKK22168.1 - 1.1e-17 64.0 2.6 1.7e-16 60.2 1.9 2.5 2 1 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.6 KKK22168.1 - 3e-05 23.6 0.3 5.3e-05 22.8 0.3 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Chlorosome_CsmC PF11098.8 KKK22168.1 - 0.24 11.4 3.4 0.44 10.5 3.4 1.3 1 0 0 1 1 1 0 Chlorosome envelope protein C Kdo PF06293.14 KKK22179.1 - 1.1e-05 24.9 0.0 1.1e-05 24.9 0.0 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 KKK22179.1 - 0.0021 17.5 0.2 0.0055 16.1 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain APH PF01636.23 KKK22179.1 - 0.0032 17.4 0.1 0.0032 17.4 0.1 2.9 2 1 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KKK22179.1 - 0.013 15.1 2.2 0.015 14.9 0.0 2.0 2 0 0 2 2 2 0 Choline/ethanolamine kinase Synaptobrevin PF00957.21 KKK22179.1 - 0.14 12.0 3.8 0.31 10.8 3.1 1.8 1 1 1 2 2 2 0 Synaptobrevin DUF2353 PF09789.9 KKK22179.1 - 0.22 10.8 17.6 0.35 10.2 17.6 1.2 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) EMP24_GP25L PF01105.24 KKK22179.1 - 0.92 9.4 7.7 1.9 8.4 7.7 1.5 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD HSP70 PF00012.20 KKK22179.1 - 3.4 5.8 14.5 4.8 5.2 14.5 1.1 1 0 0 1 1 1 0 Hsp70 protein DUF2514 PF10721.9 KKK22179.1 - 6.8 6.7 17.2 14 5.6 17.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) V_ATPase_I PF01496.19 KKK22179.1 - 9.7 4.0 9.8 14 3.4 9.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Choline_kinase PF01633.20 KKK22180.1 - 1.2e-05 25.0 0.0 1.6e-05 24.6 0.0 1.1 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 KKK22180.1 - 1.3e-05 25.3 0.1 2.5e-05 24.3 0.0 1.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family TPR_1 PF00515.28 KKK22181.1 - 4.7e-32 108.5 12.6 1.3e-06 28.0 0.0 7.5 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_2 PF07719.17 KKK22181.1 - 7.3e-32 106.9 12.5 2.8e-05 23.9 0.0 7.8 7 0 0 7 7 7 6 Tetratricopeptide repeat DnaJ PF00226.31 KKK22181.1 - 1.2e-26 92.6 2.6 2.9e-26 91.4 1.3 2.3 2 0 0 2 2 2 1 DnaJ domain TPR_19 PF14559.6 KKK22181.1 - 9e-23 80.6 17.6 1.3e-08 35.2 0.3 5.9 4 2 0 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.6 KKK22181.1 - 1.5e-21 74.7 6.3 0.0013 18.8 0.0 7.3 6 1 0 7 7 7 5 Tetratricopeptide repeat TPR_16 PF13432.6 KKK22181.1 - 6e-17 62.0 23.6 0.00022 21.8 4.0 6.5 4 2 2 6 6 5 5 Tetratricopeptide repeat TPR_11 PF13414.6 KKK22181.1 - 7.6e-14 51.1 14.7 3.2e-05 23.5 0.1 6.8 5 1 1 6 6 6 4 TPR repeat TPR_7 PF13176.6 KKK22181.1 - 6.3e-13 47.8 2.7 0.2 11.8 0.0 6.6 6 0 0 6 6 6 3 Tetratricopeptide repeat ANAPC3 PF12895.7 KKK22181.1 - 4e-12 46.2 3.0 0.14 12.4 0.1 5.0 3 2 1 4 4 4 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 KKK22181.1 - 4e-12 45.6 9.9 0.034 14.5 0.0 6.2 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 KKK22181.1 - 1.1e-11 44.5 24.5 0.019 15.8 0.1 8.2 6 2 3 9 9 7 3 Tetratricopeptide repeat TPR_9 PF13371.6 KKK22181.1 - 3.9e-11 42.9 10.3 0.00047 20.3 0.1 4.2 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_6 PF13174.6 KKK22181.1 - 1.1e-09 38.3 11.9 0.028 15.0 0.1 7.9 8 1 0 8 8 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 KKK22181.1 - 4.5e-07 30.1 11.7 0.27 11.6 0.7 6.1 4 2 0 5 5 5 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KKK22181.1 - 4.7e-07 29.8 3.6 0.56 10.3 0.1 4.4 4 0 0 4 4 4 2 Fis1 C-terminal tetratricopeptide repeat TPR_15 PF13429.6 KKK22181.1 - 5.9e-05 22.4 5.9 0.97 8.6 0.0 4.8 3 2 1 4 4 4 1 Tetratricopeptide repeat BTAD PF03704.17 KKK22181.1 - 0.00012 22.5 9.1 0.2 12.1 0.6 4.2 3 1 0 4 4 3 2 Bacterial transcriptional activator domain TPR_10 PF13374.6 KKK22181.1 - 0.0003 20.6 14.5 3 7.8 0.1 6.0 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_20 PF14561.6 KKK22181.1 - 0.0012 19.2 6.8 5.3 7.5 0.3 4.3 3 1 1 4 4 4 1 Tetratricopeptide repeat DUF4919 PF16266.5 KKK22181.1 - 0.003 17.5 1.4 3.5 7.5 0.1 3.6 3 1 0 3 3 3 1 Domain of unknown function (DUF4919) SRP_TPR_like PF17004.5 KKK22181.1 - 0.015 15.3 0.1 3.2 7.8 0.0 3.3 3 0 0 3 3 3 0 Putative TPR-like repeat SHNi-TPR PF10516.9 KKK22181.1 - 0.019 14.4 6.1 31 4.1 0.0 5.1 5 0 0 5 5 5 0 SHNi-TPR MIT PF04212.18 KKK22181.1 - 0.11 12.6 4.1 1.9 8.6 0.1 3.5 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_4 PF07721.14 KKK22181.1 - 0.12 13.0 16.7 0.24 12.1 0.1 4.7 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_MalT PF17874.1 KKK22181.1 - 0.17 11.2 1.9 13 5.0 0.0 3.1 3 0 0 3 3 3 0 MalT-like TPR region SOG2 PF10428.9 KKK22181.1 - 1.5 8.0 17.3 2.3 7.3 17.3 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein Aldo_ket_red PF00248.21 KKK22201.1 - 5.4e-55 186.7 0.0 6.1e-55 186.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Tubulin PF00091.25 KKK22202.1 - 2.2e-67 227.1 0.0 3.2e-67 226.6 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KKK22202.1 - 1.1e-44 151.6 0.9 1.7e-44 151.0 0.2 1.7 2 0 0 2 2 2 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 KKK22202.1 - 1.9e-06 28.2 0.0 5.5e-06 26.7 0.0 1.8 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Hrs_helical PF12210.8 KKK22202.1 - 0.1 13.1 0.3 0.26 11.8 0.1 1.7 2 0 0 2 2 2 0 Hepatocyte growth factor-regulated tyrosine kinase substrate Pkinase PF00069.25 KKK22203.1 - 1.7e-12 47.3 0.0 2.7e-12 46.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK22203.1 - 2e-09 37.1 0.0 5.4e-09 35.7 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 KKK22203.1 - 0.00014 21.8 0.2 0.0035 17.3 0.3 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KKK22203.1 - 0.00017 21.3 0.8 0.097 12.2 0.0 2.5 2 1 1 3 3 3 2 Choline/ethanolamine kinase Kdo PF06293.14 KKK22203.1 - 0.0054 16.1 0.0 0.0084 15.5 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1754 PF08555.10 KKK22204.1 - 2.6e-17 63.4 7.4 2.6e-17 63.4 7.4 1.5 2 0 0 2 2 2 1 Eukaryotic family of unknown function (DUF1754) zf-AN1 PF01428.16 KKK22205.1 - 7.4e-13 48.4 5.9 7.4e-13 48.4 5.9 1.6 1 1 0 1 1 1 1 AN1-like Zinc finger Transp_Tc5_C PF04236.15 KKK22205.1 - 0.18 12.2 6.5 0.096 13.1 4.6 1.5 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain DUF202 PF02656.15 KKK22206.1 - 2.2e-22 79.3 0.8 2.2e-22 79.3 0.8 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF202) PTPA PF03095.15 KKK22207.1 - 1.3e-110 369.6 0.0 1.6e-110 369.3 0.0 1.1 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Reprolysin_4 PF13583.6 KKK22208.1 - 9.1e-35 120.1 0.5 9.1e-35 120.1 0.5 1.8 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 KKK22208.1 - 1.1e-30 107.3 1.6 1.1e-30 107.3 1.6 1.8 2 0 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.6 KKK22208.1 - 4.2e-16 59.4 1.8 4.5e-16 59.3 0.1 1.8 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Pep_M12B_propep PF01562.19 KKK22208.1 - 0.00062 20.0 0.1 0.0025 18.0 0.0 2.0 1 1 0 1 1 1 1 Reprolysin family propeptide Reprolysin PF01421.19 KKK22208.1 - 0.0011 18.9 0.1 0.0064 16.4 0.1 2.0 1 1 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Actin PF00022.19 KKK22209.1 - 3.1e-89 299.4 0.0 2.2e-77 260.4 0.0 2.8 2 1 0 2 2 2 2 Actin MreB_Mbl PF06723.13 KKK22209.1 - 0.14 10.9 0.0 0.48 9.2 0.0 1.7 1 1 0 1 1 1 0 MreB/Mbl protein Actin_micro PF17003.5 KKK22209.1 - 0.29 10.3 0.5 1.1 8.4 0.1 1.9 2 0 0 2 2 2 0 Putative actin-like family DUF3425 PF11905.8 KKK22210.1 - 8e-23 80.8 1.2 1.3e-22 80.1 1.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 KKK22210.1 - 0.0028 17.7 8.5 0.024 14.7 6.1 2.4 1 1 1 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 KKK22210.1 - 0.34 11.0 11.6 2.3 8.4 11.6 2.2 1 1 0 1 1 1 0 Basic region leucine zipper MCPVI PF02993.14 KKK22210.1 - 0.77 9.6 6.1 0.88 9.4 4.5 1.8 1 1 1 2 2 2 0 Minor capsid protein VI NAD_binding_2 PF03446.15 KKK22211.1 - 2.9e-28 99.0 0.1 4.3e-28 98.5 0.1 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 KKK22211.1 - 3.6e-11 43.4 0.0 6.7e-11 42.5 0.0 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 KKK22211.1 - 0.0025 18.3 0.0 0.0082 16.7 0.0 1.9 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent RuvC_1 PF18516.1 KKK22211.1 - 0.026 13.7 0.0 0.034 13.3 0.0 1.1 1 0 0 1 1 1 0 RuvC nuclease domain Shikimate_DH PF01488.20 KKK22211.1 - 0.07 13.2 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF1325 PF07039.11 KKK22212.1 - 8.7e-34 116.4 0.0 1.5e-33 115.7 0.0 1.4 1 0 0 1 1 1 1 SGF29 tudor-like domain LBR_tudor PF09465.10 KKK22212.1 - 0.013 15.2 0.0 0.024 14.4 0.0 1.4 1 0 0 1 1 1 0 Lamin-B receptor of TUDOR domain GTP_cyclohydro2 PF00925.20 KKK22213.1 - 3e-57 192.8 0.0 4.3e-57 192.3 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase II Coatomer_E PF04733.14 KKK22214.1 - 2.8e-38 132.0 0.5 3.2e-38 131.8 0.5 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_19 PF14559.6 KKK22214.1 - 3.1e-06 27.6 4.8 0.0003 21.2 0.6 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 KKK22214.1 - 0.00085 19.9 5.0 0.01 16.6 0.3 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 KKK22214.1 - 0.0012 18.8 2.5 0.025 14.7 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 KKK22214.1 - 0.0019 18.8 8.1 0.0057 17.3 1.5 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 KKK22214.1 - 0.019 15.1 2.2 1.5 9.0 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 KKK22214.1 - 0.025 14.4 0.1 0.18 11.7 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 KKK22214.1 - 0.079 13.3 3.4 0.3 11.4 0.2 2.6 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_4 PF07721.14 KKK22214.1 - 1.5 9.6 5.7 1 10.2 0.6 3.1 3 1 1 4 4 4 0 Tetratricopeptide repeat PMI_typeI PF01238.21 KKK22215.1 - 8.3e-149 495.8 0.0 9.6e-149 495.6 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I Cupin_2 PF07883.11 KKK22215.1 - 0.025 14.3 0.1 0.47 10.2 0.0 2.2 2 0 0 2 2 2 0 Cupin domain AraC_binding PF02311.19 KKK22215.1 - 0.069 13.1 0.0 18 5.2 0.0 2.9 3 0 0 3 3 3 0 AraC-like ligand binding domain IRK_C PF17655.1 KKK22215.1 - 0.21 11.2 0.0 0.34 10.5 0.0 1.3 1 0 0 1 1 1 0 Inward rectifier potassium channel C-terminal domain EamA PF00892.20 KKK22216.1 - 4.3e-11 43.1 28.9 3.6e-05 23.9 0.8 2.4 2 0 0 2 2 2 2 EamA-like transporter family Metallophos PF00149.28 KKK22216.1 - 5.4e-10 40.1 0.0 1.2e-09 39.0 0.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KKK22216.1 - 2.5e-06 27.8 0.0 3e-05 24.3 0.0 2.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain CSG2 PF16965.5 KKK22216.1 - 8.3e-06 25.0 9.8 3.2e-05 23.0 9.8 2.0 1 1 0 1 1 1 1 Ceramide synthase regulator MASE3 PF17159.4 KKK22216.1 - 0.0087 15.7 2.1 0.0087 15.7 2.1 2.1 2 0 0 2 2 2 1 Membrane-associated sensor domain DUF202 PF02656.15 KKK22216.1 - 0.0097 16.3 2.8 0.0097 16.3 2.8 4.4 3 2 1 4 4 4 1 Domain of unknown function (DUF202) Nuc_sug_transp PF04142.15 KKK22216.1 - 0.41 9.8 7.7 1.4 8.0 5.2 2.6 2 1 0 2 2 2 0 Nucleotide-sugar transporter Pkinase PF00069.25 KKK22217.1 - 2.4e-21 76.3 0.0 1.2e-20 74.0 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK22217.1 - 0.00036 19.9 0.0 0.00087 18.6 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Ribosomal_S30 PF04758.14 KKK22231.1 - 6.3e-18 64.7 7.5 6.6e-18 64.6 7.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 GATA PF00320.27 KKK22240.1 - 9.4e-16 57.1 2.4 1.6e-15 56.4 2.4 1.4 1 0 0 1 1 1 1 GATA zinc finger Pox_A_type_inc PF04508.12 KKK22240.1 - 0.0036 17.1 4.5 0.39 10.7 0.7 3.3 3 0 0 3 3 3 2 Viral A-type inclusion protein repeat CENP-F_N PF10481.9 KKK22240.1 - 0.015 14.9 0.9 0.72 9.4 0.0 2.2 2 0 0 2 2 2 0 Cenp-F N-terminal domain DivIVA PF05103.13 KKK22240.1 - 0.023 14.7 4.0 0.8 9.8 4.0 2.1 1 1 0 1 1 1 0 DivIVA protein TF_Zn_Ribbon PF08271.12 KKK22240.1 - 0.028 13.9 0.3 0.052 13.1 0.3 1.4 1 0 0 1 1 1 0 TFIIB zinc-binding GAS PF13851.6 KKK22240.1 - 0.063 12.6 1.9 0.095 12.0 1.9 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding ArfGap PF01412.18 KKK22240.1 - 0.096 12.8 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 Putative GTPase activating protein for Arf BBP1_C PF15272.6 KKK22240.1 - 0.12 12.2 1.1 0.19 11.6 1.1 1.3 1 0 0 1 1 1 0 Spindle pole body component BBP1, C-terminal CLZ PF16526.5 KKK22240.1 - 0.15 12.4 5.0 0.76 10.2 3.1 2.3 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels eIF-5_eIF-2B PF01873.17 KKK22240.1 - 0.16 11.8 0.2 0.28 11.1 0.2 1.4 1 0 0 1 1 1 0 Domain found in IF2B/IF5 APH PF01636.23 KKK22259.1 - 1.2e-12 48.3 0.0 5.9e-12 46.0 0.0 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KKK22259.1 - 0.047 13.3 2.1 0.063 12.9 0.1 1.9 2 0 0 2 2 2 0 Choline/ethanolamine kinase CPL PF08144.11 KKK22297.1 - 8.3e-31 107.3 0.4 1.7e-28 99.8 0.0 3.3 3 0 0 3 3 3 1 CPL (NUC119) domain BSP_II PF05432.11 KKK22297.1 - 0.32 10.6 21.1 0.51 10.0 21.1 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) LAP1C PF05609.12 KKK22297.1 - 0.37 9.8 15.6 0.56 9.2 15.6 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) CDC27 PF09507.10 KKK22297.1 - 3.3 7.0 26.6 6.7 6.0 26.6 1.4 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 CDC45 PF02724.14 KKK22297.1 - 3.4 5.9 17.9 5 5.3 17.9 1.3 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 KKK22297.1 - 4.8 5.3 29.4 0.84 7.8 25.6 1.6 2 0 0 2 2 2 0 Nop14-like family RRN3 PF05327.11 KKK22297.1 - 9.9 4.6 13.9 18 3.7 13.9 1.5 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Rad51 PF08423.11 KKK22298.1 - 1.2e-128 427.8 0.0 1.6e-128 427.4 0.0 1.2 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.6 KKK22298.1 - 7.7e-10 38.7 0.0 1.6e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain RecA PF00154.21 KKK22298.1 - 5.1e-09 36.0 0.0 7.8e-09 35.4 0.0 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein HHH_5 PF14520.6 KKK22298.1 - 4.1e-05 24.1 0.4 0.00011 22.8 0.2 1.8 2 0 0 2 2 2 1 Helix-hairpin-helix domain ATPase PF06745.13 KKK22298.1 - 0.00013 21.4 1.2 0.00052 19.4 1.2 2.0 1 1 0 1 1 1 1 KaiC DnaB_C PF03796.15 KKK22298.1 - 0.023 14.1 0.1 0.12 11.7 0.0 2.0 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain PAXNEB PF05625.11 KKK22298.1 - 0.11 11.6 0.6 0.32 10.1 0.1 1.9 2 0 0 2 2 2 0 PAXNEB protein ABC_tran PF00005.27 KKK22299.1 - 3e-34 118.5 0.0 9.8e-16 58.5 0.1 3.6 3 0 0 3 3 3 3 ABC transporter ABC_membrane PF00664.23 KKK22299.1 - 1.6e-24 87.0 22.8 1.2e-21 77.6 6.5 2.6 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 KKK22299.1 - 2.8e-07 30.2 0.5 0.00089 18.7 0.0 3.1 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 KKK22299.1 - 0.00025 21.0 0.1 0.0013 18.7 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase AAA_21 PF13304.6 KKK22299.1 - 0.00079 19.3 0.1 0.13 12.1 0.0 2.8 2 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KKK22299.1 - 0.00093 19.6 0.0 0.063 13.7 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 KKK22299.1 - 0.0013 19.2 0.6 0.032 14.7 0.0 3.2 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 KKK22299.1 - 0.0016 18.8 0.1 0.24 11.8 0.0 3.1 2 1 1 3 3 2 1 RNA helicase AAA_29 PF13555.6 KKK22299.1 - 0.0017 18.1 0.1 0.0056 16.4 0.1 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_33 PF13671.6 KKK22299.1 - 0.0088 16.2 0.1 0.032 14.4 0.1 1.9 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KKK22299.1 - 0.029 14.7 0.5 0.22 11.8 0.0 2.4 2 1 0 2 2 2 0 AAA domain AAA_23 PF13476.6 KKK22299.1 - 0.043 14.3 0.2 0.095 13.2 0.2 1.5 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 KKK22299.1 - 0.047 13.8 0.0 0.3 11.2 0.0 2.2 2 0 0 2 2 2 0 50S ribosome-binding GTPase SbcCD_C PF13558.6 KKK22299.1 - 0.058 13.6 0.0 21 5.4 0.0 2.7 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.6 KKK22299.1 - 0.097 12.4 0.3 3.8 7.2 0.1 2.3 2 0 0 2 2 2 0 AAA domain Nup160 PF11715.8 KKK22300.1 - 5.1e-173 576.6 0.7 7.3e-173 576.1 0.7 1.2 1 0 0 1 1 1 1 Nucleoporin Nup120/160 MFS_1 PF07690.16 KKK22301.1 - 6.9e-36 123.9 42.6 6.9e-36 123.9 42.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KKK22301.1 - 0.00015 20.3 2.6 0.00015 20.3 2.6 2.2 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Phage_holin_2_3 PF16080.5 KKK22301.1 - 9.6 6.1 8.3 1.3 8.8 0.0 3.6 3 1 0 3 3 3 0 Bacteriophage holin family HP1 AMP-binding PF00501.28 KKK22302.1 - 3.3e-269 892.4 0.0 2.1e-77 260.5 0.0 4.2 4 0 0 4 4 4 4 AMP-binding enzyme Condensation PF00668.20 KKK22302.1 - 2.2e-260 863.9 0.0 3.2e-57 194.2 0.0 10.4 8 3 1 9 9 9 9 Condensation domain PP-binding PF00550.25 KKK22302.1 - 7.3e-48 160.8 0.0 1.4e-11 44.5 0.0 6.0 5 0 0 5 5 5 5 Phosphopantetheine attachment site Transferase PF02458.15 KKK22302.1 - 0.00063 18.5 0.0 1.1 7.9 0.0 3.6 4 0 0 4 4 4 2 Transferase family AMP-binding_C PF13193.6 KKK22302.1 - 0.0084 17.1 0.0 0.43 11.6 0.0 3.6 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain TOM13 PF08219.11 KKK22305.1 - 8.6e-37 125.0 0.0 1.1e-36 124.6 0.0 1.1 1 0 0 1 1 1 1 Outer membrane protein TOM13 60KD_IMP PF02096.20 KKK22306.1 - 6.9e-23 81.4 0.0 2.1e-22 79.8 0.1 1.7 2 0 0 2 2 2 1 60Kd inner membrane protein COG2 PF06148.11 KKK22308.1 - 3e-38 130.9 3.3 3e-38 130.9 3.3 1.7 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 COG5 PF10392.9 KKK22308.1 - 1.2e-05 25.5 1.5 1.2e-05 25.5 1.5 2.1 2 0 0 2 2 2 1 Golgi transport complex subunit 5 Vps51 PF08700.11 KKK22308.1 - 2.2e-05 24.4 2.5 0.00019 21.5 2.5 2.5 1 1 0 1 1 1 1 Vps51/Vps67 Vps54_N PF10475.9 KKK22308.1 - 0.006 15.9 0.1 0.011 15.1 0.1 1.4 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex Bul1_C PF04426.12 KKK22308.1 - 0.054 12.9 0.3 0.11 11.9 0.1 1.5 1 1 0 1 1 1 0 Bul1 C terminus STAR_dimer PF16544.5 KKK22308.1 - 0.091 12.3 2.2 7.6 6.2 0.4 2.4 2 0 0 2 2 2 0 Homodimerisation region of STAR domain protein Sec34 PF04136.15 KKK22308.1 - 0.18 11.7 2.7 0.35 10.8 0.2 2.3 1 1 1 2 2 2 0 Sec34-like family Exonuc_VII_L PF02601.15 KKK22308.1 - 0.4 10.2 9.8 1.1 8.8 3.1 2.1 1 1 0 2 2 2 0 Exonuclease VII, large subunit Bcr-Abl_Oligo PF09036.10 KKK22308.1 - 0.53 10.3 0.0 0.53 10.3 0.0 2.7 4 0 0 4 4 4 0 Bcr-Abl oncoprotein oligomerisation domain PXA PF02194.15 KKK22308.1 - 0.58 10.1 2.9 1.2 9.1 2.9 1.7 1 1 0 1 1 1 0 PXA domain DUF1664 PF07889.12 KKK22308.1 - 0.89 9.6 3.6 0.61 10.1 1.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Spc7 PF08317.11 KKK22308.1 - 1.4 7.7 9.9 0.22 10.4 5.3 1.8 2 0 0 2 2 2 0 Spc7 kinetochore protein TolA_bind_tri PF16331.5 KKK22308.1 - 1.4 9.0 17.5 0.078 13.1 1.2 4.0 4 0 0 4 4 4 0 TolA binding protein trimerisation FlaC_arch PF05377.11 KKK22308.1 - 1.7 9.1 10.0 1.2 9.6 1.2 3.7 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) NPV_P10 PF05531.12 KKK22308.1 - 1.8 9.1 5.0 5.4 7.6 0.8 2.9 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein SEP PF08059.13 KKK22309.1 - 6.3e-26 90.8 0.1 1.4e-25 89.7 0.1 1.6 1 0 0 1 1 1 1 SEP domain UBX PF00789.20 KKK22309.1 - 8.6e-15 54.7 0.0 1.4e-14 54.0 0.0 1.4 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.6 KKK22309.1 - 3.5e-13 49.1 1.7 6.3e-13 48.3 1.7 1.4 1 0 0 1 1 1 1 UBA-like domain TAP_C PF03943.13 KKK22309.1 - 0.00025 20.6 0.1 0.00048 19.7 0.1 1.4 1 0 0 1 1 1 1 TAP C-terminal domain ParA PF10609.9 KKK22310.1 - 5.9e-85 284.6 0.1 5.7e-57 193.0 0.0 2.2 1 1 1 2 2 2 2 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 KKK22310.1 - 2e-09 37.6 0.0 4.6e-09 36.4 0.0 1.6 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.11 KKK22310.1 - 6.5e-07 28.9 0.0 4.2e-06 26.3 0.0 1.9 2 0 0 2 2 2 1 ATPase MipZ AAA_31 PF13614.6 KKK22310.1 - 3.8e-05 23.7 0.4 0.00031 20.7 0.4 2.0 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KKK22310.1 - 0.00065 19.3 0.2 0.0011 18.6 0.2 1.3 1 0 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.15 KKK22310.1 - 0.00098 18.4 0.7 0.0019 17.5 0.7 1.4 1 0 0 1 1 1 1 Anion-transporting ATPase MeaB PF03308.16 KKK22310.1 - 0.011 14.7 0.5 0.017 14.1 0.5 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB CBP_BcsQ PF06564.12 KKK22310.1 - 0.011 15.2 0.4 0.063 12.7 0.2 2.0 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsQ APS_kinase PF01583.20 KKK22310.1 - 0.077 12.9 0.1 0.12 12.3 0.1 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase Fer4_NifH PF00142.18 KKK22310.1 - 0.13 11.7 0.0 0.21 11.0 0.0 1.2 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_26 PF13500.6 KKK22310.1 - 0.18 11.6 1.3 4.8 6.9 0.7 2.3 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 KKK22310.1 - 1.3 8.9 3.3 1.2 9.0 1.3 1.8 2 0 0 2 2 2 0 RsgA GTPase Guanylate_kin PF00625.21 KKK22334.1 - 5.3e-49 166.4 0.0 6.1e-49 166.2 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase DUF2183 PF09949.9 KKK22342.1 - 5.2e-33 113.3 0.2 1.1e-32 112.3 0.2 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) LNS2 PF08235.13 KKK22342.1 - 0.00028 20.4 0.0 0.00042 19.9 0.0 1.2 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) GPP34 PF05719.11 KKK22343.1 - 8e-43 146.8 0.1 1e-42 146.5 0.1 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) TRAPPC9-Trs120 PF08626.11 KKK22343.1 - 0.13 9.6 0.0 0.16 9.3 0.0 1.0 1 0 0 1 1 1 0 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit VHS PF00790.19 KKK22345.1 - 7.1e-34 116.7 1.2 1.7e-32 112.2 0.3 2.9 2 1 0 2 2 2 1 VHS domain Alpha_adaptinC2 PF02883.20 KKK22345.1 - 3.2e-22 78.9 0.1 3.2e-22 78.9 0.1 1.6 2 0 0 2 2 2 1 Adaptin C-terminal domain GAT PF03127.14 KKK22345.1 - 4.2e-21 75.0 0.3 1.2e-20 73.6 0.0 2.0 2 0 0 2 2 2 1 GAT domain GGA_N-GAT PF18308.1 KKK22345.1 - 2e-10 40.1 0.5 4.2e-07 29.5 0.1 3.1 2 0 0 2 2 2 2 GGA N-GAT domain Mei5 PF10376.9 KKK22345.1 - 0.064 13.1 1.2 0.13 12.1 1.2 1.5 1 0 0 1 1 1 0 Double-strand recombination repair protein CBS PF00571.28 KKK22347.1 - 7.2e-21 74.4 7.0 2.8e-06 27.7 0.0 5.3 5 0 0 5 5 5 5 CBS domain Mcp5_PH PF12814.7 KKK22360.1 - 1.2e-47 161.0 0.0 2.5e-47 160.0 0.0 1.6 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology Fez1 PF06818.15 KKK22360.1 - 0.0012 19.4 11.1 0.0026 18.3 11.1 1.5 1 0 0 1 1 1 1 Fez1 DUF724 PF05266.14 KKK22360.1 - 0.0029 17.4 3.9 0.0049 16.7 3.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF724) Macoilin PF09726.9 KKK22360.1 - 0.0035 16.0 0.7 0.0035 16.0 0.7 2.2 2 0 0 2 2 2 1 Macoilin family zf-C4H2 PF10146.9 KKK22360.1 - 0.0039 17.5 1.2 0.0039 17.5 1.2 4.0 4 1 0 4 4 3 1 Zinc finger-containing protein TPR_MLP1_2 PF07926.12 KKK22360.1 - 0.0073 16.4 16.1 0.028 14.5 14.0 2.4 1 1 1 2 2 2 1 TPR/MLP1/MLP2-like protein MscS_porin PF12795.7 KKK22360.1 - 0.023 14.3 7.3 0.044 13.3 7.3 1.4 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain Lebercilin PF15619.6 KKK22360.1 - 0.041 13.5 13.5 0.075 12.7 13.5 1.4 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease UPF0242 PF06785.11 KKK22360.1 - 0.055 13.6 7.3 0.093 12.8 7.3 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Exonuc_VII_L PF02601.15 KKK22360.1 - 0.15 11.6 5.5 0.31 10.6 5.5 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit TACC_C PF05010.14 KKK22360.1 - 0.2 11.4 6.1 0.38 10.5 6.1 1.4 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Spore_III_AB PF09548.10 KKK22360.1 - 0.24 11.5 0.9 0.41 10.7 0.9 1.3 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) GAS PF13851.6 KKK22360.1 - 0.24 10.7 15.8 0.21 10.9 2.5 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding TMF_DNA_bd PF12329.8 KKK22360.1 - 0.58 10.2 10.1 0.63 10.1 1.4 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Golgin_A5 PF09787.9 KKK22360.1 - 0.76 9.2 11.6 1.4 8.3 11.6 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 CorA PF01544.18 KKK22360.1 - 0.85 8.9 4.0 1.4 8.2 4.0 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein APG6_N PF17675.1 KKK22360.1 - 1.8 9.1 11.1 3.8 8.1 11.1 1.5 1 0 0 1 1 1 0 Apg6 coiled-coil region Fib_alpha PF08702.10 KKK22360.1 - 2.4 8.3 4.5 28 4.9 0.6 2.3 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Tropomyosin_1 PF12718.7 KKK22360.1 - 4.7 7.4 14.9 13 6.0 14.9 1.7 1 1 0 1 1 1 0 Tropomyosin like BRE1 PF08647.11 KKK22360.1 - 7.4 6.7 10.0 2.4 8.3 2.1 2.4 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase Spc7 PF08317.11 KKK22360.1 - 9 5.1 10.2 18 4.1 10.2 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein Methyltransf_23 PF13489.6 KKK22370.1 - 2.4e-09 37.2 0.0 3.3e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKK22370.1 - 3.2e-08 34.2 0.0 5.8e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KKK22370.1 - 3.9e-05 23.5 0.0 5.7e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KKK22370.1 - 0.00025 21.6 0.0 0.00045 20.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KKK22370.1 - 0.0069 15.7 0.0 0.01 15.2 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family HNH_repeat PF18780.1 KKK22370.1 - 0.36 10.7 1.8 1.4 8.8 0.0 2.3 2 0 0 2 2 2 0 Homing endonuclease repeat Aminotran_1_2 PF00155.21 KKK22371.1 - 6.2e-40 137.5 0.0 7.5e-40 137.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 KKK22371.1 - 0.045 13.0 0.0 0.056 12.7 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase DUF4585 PF15232.6 KKK22371.1 - 0.064 13.3 0.0 0.17 11.9 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4585) Trp_DMAT PF11991.8 KKK22372.1 - 1.6e-96 323.9 0.0 2e-96 323.6 0.0 1.1 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase p450 PF00067.22 KKK22373.1 - 3.7e-43 148.0 0.0 5.4e-43 147.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 DivIC PF04977.15 KKK22373.1 - 0.12 12.2 0.3 0.22 11.3 0.3 1.4 1 0 0 1 1 1 0 Septum formation initiator GST_N_3 PF13417.6 KKK22374.1 - 1.3e-06 28.7 0.1 3.2e-06 27.4 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KKK22374.1 - 5.4e-06 26.5 0.0 9.2e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KKK22374.1 - 2e-05 24.5 0.1 5.2e-05 23.2 0.1 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KKK22374.1 - 6.3e-05 23.2 0.0 0.00013 22.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KKK22374.1 - 0.0019 18.4 0.0 0.0031 17.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain UPF0149 PF03695.13 KKK22374.1 - 0.011 16.0 0.0 0.017 15.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0149) GST_N PF02798.20 KKK22374.1 - 0.046 14.1 0.0 0.17 12.3 0.0 2.0 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain PAP2_3 PF14378.6 KKK22375.1 - 5.9e-24 84.8 11.8 5.9e-24 84.8 11.8 1.8 2 0 0 2 2 2 1 PAP2 superfamily PAP2 PF01569.21 KKK22375.1 - 6.8e-11 42.1 2.4 6.8e-11 42.1 2.4 2.1 2 0 0 2 2 2 1 PAP2 superfamily Methyltransf_23 PF13489.6 KKK22376.1 - 4.6e-11 42.8 0.0 6.3e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKK22376.1 - 0.00049 20.7 0.0 0.0014 19.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KKK22376.1 - 0.011 16.4 0.0 0.019 15.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 KKK22376.1 - 0.015 15.1 0.0 5.1 6.9 0.0 2.8 2 1 1 3 3 3 0 Methyltransferase domain Methyltransf_11 PF08241.12 KKK22376.1 - 0.072 13.7 0.0 0.14 12.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Pyr_redox_2 PF07992.14 KKK22377.1 - 9.3e-19 67.8 0.0 1.7e-18 66.9 0.0 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KKK22377.1 - 3.3e-07 29.8 0.1 0.0024 17.2 0.0 2.9 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KKK22377.1 - 6e-06 25.6 0.5 1.2e-05 24.6 0.1 1.7 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 KKK22377.1 - 2.6e-05 23.1 0.3 0.0014 17.5 0.1 2.2 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.24 KKK22377.1 - 5.1e-05 23.0 0.1 0.012 15.3 0.2 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KKK22377.1 - 0.00014 22.0 0.1 0.00035 20.7 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 KKK22377.1 - 0.00032 20.1 0.0 0.00059 19.2 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.6 KKK22377.1 - 0.00077 19.5 0.2 0.28 11.2 0.1 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding Thi4 PF01946.17 KKK22377.1 - 0.0015 17.8 0.0 0.0029 16.9 0.0 1.4 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.22 KKK22377.1 - 0.0019 17.4 0.3 0.12 11.4 0.1 2.9 3 0 0 3 3 3 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 KKK22377.1 - 0.021 14.2 0.4 0.031 13.6 0.4 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase K_oxygenase PF13434.6 KKK22377.1 - 0.072 12.2 0.0 10 5.2 0.0 2.3 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) UBX PF00789.20 KKK22377.1 - 0.15 12.3 0.0 0.28 11.4 0.0 1.4 1 0 0 1 1 1 0 UBX domain Lycopene_cycl PF05834.12 KKK22377.1 - 0.16 11.0 0.5 0.54 9.3 0.3 1.8 1 1 1 2 2 2 0 Lycopene cyclase protein Glu_dehyd_C PF16912.5 KKK22377.1 - 0.16 11.4 0.1 0.42 10.1 0.0 1.7 1 1 1 2 2 2 0 Glucose dehydrogenase C-terminus AMP-binding PF00501.28 KKK22378.1 - 1e-133 446.1 0.0 1.3e-73 248.0 0.0 3.2 2 1 1 3 3 3 3 AMP-binding enzyme Condensation PF00668.20 KKK22378.1 - 1.1e-77 261.7 0.0 3.1e-45 154.7 0.0 2.9 2 1 0 2 2 2 2 Condensation domain PP-binding PF00550.25 KKK22378.1 - 1.4e-16 60.6 0.1 2.4e-08 34.2 0.1 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KKK22378.1 - 2.7e-11 44.3 0.5 2.7e-06 28.3 0.2 2.6 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain DUF3632 PF12311.8 KKK22379.1 - 3.7e-30 105.6 0.0 5.1e-30 105.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) Carot_N PF09150.10 KKK22379.1 - 0.021 14.7 0.0 4.3 7.2 0.0 2.9 3 0 0 3 3 3 0 Orange carotenoid protein, N-terminal Bradykinin PF06753.12 KKK22379.1 - 0.35 10.6 3.4 0.14 11.8 0.8 1.7 2 0 0 2 2 2 0 Bradykinin ketoacyl-synt PF00109.26 KKK22380.1 - 4.2e-68 229.6 0.0 4.2e-68 229.6 0.0 2.7 3 0 0 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 KKK22380.1 - 1.7e-54 185.5 0.0 4.6e-54 184.1 0.0 1.8 2 0 0 2 2 2 1 Acyl transferase domain PS-DH PF14765.6 KKK22380.1 - 2.4e-41 141.9 0.3 4.4e-41 141.0 0.3 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 KKK22380.1 - 7.1e-34 116.4 0.2 2.5e-33 114.6 0.1 2.1 2 0 0 2 2 1 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.10 KKK22380.1 - 9.3e-29 100.6 0.0 2.1e-28 99.4 0.0 1.7 1 0 0 1 1 1 1 KR domain KAsynt_C_assoc PF16197.5 KKK22380.1 - 5.1e-19 68.8 0.0 1.3e-18 67.4 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_12 PF08242.12 KKK22380.1 - 1.3e-18 67.6 0.0 3.1e-18 66.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KKK22380.1 - 3.3e-11 43.3 0.0 1.1e-10 41.6 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKK22380.1 - 6.5e-10 39.6 0.0 2.8e-09 37.6 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.25 KKK22380.1 - 8e-07 29.3 0.3 2.1e-06 28.0 0.3 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_31 PF13847.6 KKK22380.1 - 1.1e-06 28.5 0.0 2.1e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KKK22380.1 - 1.3e-06 28.9 0.0 4.5e-06 27.2 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.23 KKK22380.1 - 0.00045 19.7 0.1 0.0012 18.2 0.1 1.7 1 0 0 1 1 1 1 Thiolase, N-terminal domain Ubie_methyltran PF01209.18 KKK22380.1 - 0.012 15.0 0.0 0.021 14.1 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family adh_short PF00106.25 KKK22380.1 - 0.012 15.1 0.0 0.044 13.2 0.0 2.0 1 0 0 1 1 1 0 short chain dehydrogenase ACP_syn_III PF08545.10 KKK22380.1 - 0.065 13.1 2.0 0.13 12.1 0.6 2.3 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III CMD PF02627.20 KKK22381.1 - 0.024 14.7 7.1 0.56 10.3 0.2 3.3 3 2 0 3 3 3 0 Carboxymuconolactone decarboxylase family MFS_1 PF07690.16 KKK22382.1 - 1.4e-40 139.3 63.9 5.3e-32 111.1 37.0 3.5 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KKK22382.1 - 6.9e-24 84.2 20.5 9e-24 83.8 20.5 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KKK22382.1 - 1.3e-12 47.3 11.0 1.3e-12 47.3 11.0 2.7 3 0 0 3 3 3 2 Sugar (and other) transporter CBM_4_9 PF02018.17 KKK22383.1 - 2.3e-09 37.6 4.0 6.3e-09 36.2 4.0 1.8 1 0 0 1 1 1 1 Carbohydrate binding domain FAD_binding_3 PF01494.19 KKK22384.1 - 1e-25 90.7 6.2 1.4e-23 83.7 6.2 2.9 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KKK22384.1 - 6.2e-05 22.7 0.0 0.0038 16.9 0.1 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KKK22384.1 - 0.00087 18.5 0.2 0.00087 18.5 0.2 2.0 3 0 0 3 3 3 1 FAD binding domain NAD_binding_8 PF13450.6 KKK22384.1 - 0.00099 19.3 0.2 0.0035 17.5 0.2 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KKK22384.1 - 0.0047 16.2 0.3 0.022 14.0 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KKK22384.1 - 0.019 14.1 1.3 0.13 11.3 1.3 2.2 1 1 0 1 1 1 0 Lycopene cyclase protein Thi4 PF01946.17 KKK22384.1 - 0.04 13.1 0.1 0.071 12.3 0.1 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox_2 PF07992.14 KKK22385.1 - 9.4e-15 54.6 0.0 1.1e-12 47.9 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KKK22385.1 - 2.5e-13 50.1 0.0 5.9e-09 36.0 0.0 3.1 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FMO-like PF00743.19 KKK22385.1 - 5.1e-11 41.7 0.0 2.4e-07 29.6 0.0 2.4 3 0 0 3 3 3 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KKK22385.1 - 3.4e-09 36.4 0.0 0.00029 20.2 0.0 2.8 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KKK22385.1 - 1.8e-07 31.6 0.2 0.013 16.1 0.0 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KKK22385.1 - 2.1e-06 27.1 0.1 0.00018 20.8 0.0 2.6 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 KKK22385.1 - 2.2e-06 27.5 0.0 0.00014 21.5 0.0 3.2 4 0 0 4 4 4 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KKK22385.1 - 6.9e-06 26.1 0.3 0.026 14.5 0.0 3.4 3 0 0 3 3 3 1 FAD-NAD(P)-binding adh_short PF00106.25 KKK22385.1 - 1.5e-05 24.5 0.0 8.7e-05 22.1 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase HI0933_like PF03486.14 KKK22385.1 - 2.7e-05 23.0 0.4 0.067 11.9 0.0 2.4 3 0 0 3 3 3 2 HI0933-like protein Thi4 PF01946.17 KKK22385.1 - 6.1e-05 22.4 0.0 0.021 14.1 0.0 2.8 3 0 0 3 3 3 1 Thi4 family adh_short_C2 PF13561.6 KKK22385.1 - 7.5e-05 22.4 0.0 0.00013 21.6 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase FAD_binding_3 PF01494.19 KKK22385.1 - 0.00038 19.8 0.1 0.015 14.5 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain FAD_binding_2 PF00890.24 KKK22385.1 - 0.0011 18.2 0.0 0.0095 15.0 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain 2-Hacid_dh_C PF02826.19 KKK22385.1 - 0.002 17.5 0.0 0.032 13.6 0.0 2.3 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.16 KKK22385.1 - 0.024 14.3 0.3 3.2 7.4 0.2 2.4 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.20 KKK22385.1 - 0.056 13.5 0.0 4.7 7.3 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.21 KKK22385.1 - 0.068 12.6 0.5 5.2 6.4 0.0 2.3 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family FAD_oxidored PF12831.7 KKK22385.1 - 0.12 11.7 0.0 7.7 5.7 0.0 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 KKK22385.1 - 0.15 12.5 0.0 27 5.3 0.0 2.5 2 0 0 2 2 2 0 Putative NAD(P)-binding HK PF02110.15 KKK22385.1 - 0.18 11.2 0.1 0.29 10.5 0.1 1.2 1 0 0 1 1 1 0 Hydroxyethylthiazole kinase family adh_short PF00106.25 KKK22386.1 - 7.1e-25 87.6 0.0 9.7e-25 87.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KKK22386.1 - 6.8e-15 55.3 0.0 8.8e-15 54.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Pyr_redox_3 PF13738.6 KKK22387.1 - 2.1e-06 27.2 0.2 0.008 15.5 0.0 2.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KKK22387.1 - 0.00018 20.8 0.0 0.0041 16.4 0.0 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KKK22387.1 - 0.00025 19.6 0.8 0.0036 15.8 0.0 2.6 2 1 1 3 3 3 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 KKK22387.1 - 0.0026 17.0 0.4 0.084 12.0 0.1 2.6 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 KKK22387.1 - 0.31 10.6 2.5 1.4 8.4 1.6 2.3 2 1 0 3 3 3 0 FAD dependent oxidoreductase DUF1365 PF07103.11 KKK22388.1 - 1.5e-23 83.7 0.0 2.1e-23 83.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1365) Asp PF00026.23 KKK22389.1 - 1e-50 173.0 0.0 1.4e-50 172.5 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KKK22389.1 - 1.9e-07 31.5 0.3 8.8e-06 26.1 0.3 2.3 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KKK22389.1 - 0.0024 18.5 0.1 0.085 13.5 0.0 2.9 2 1 0 2 2 2 1 Aspartyl protease DUF3900 PF13039.6 KKK22389.1 - 0.28 11.1 0.0 0.41 10.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3900) MARVEL PF01284.23 KKK22390.1 - 2.9e-12 46.8 21.3 4.3e-12 46.3 21.3 1.2 1 0 0 1 1 1 1 Membrane-associating domain PRCC PF10253.9 KKK22390.1 - 0.12 13.2 3.0 0.14 12.9 3.0 1.1 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting 7TMR-DISM_7TM PF07695.11 KKK22390.1 - 0.19 11.6 20.1 1 9.2 5.9 2.0 1 1 1 2 2 2 0 7TM diverse intracellular signalling Pkinase PF00069.25 KKK22391.1 - 1.4e-12 47.5 0.0 2e-12 47.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK22391.1 - 0.00016 21.0 0.0 0.00021 20.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Lipase_3 PF01764.25 KKK22392.1 - 1.3e-35 122.3 0.0 1.8e-35 121.8 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Lipase3_N PF03893.16 KKK22392.1 - 5e-08 32.9 0.3 1.2e-07 31.7 0.3 1.6 1 0 0 1 1 1 1 Lipase 3 N-terminal region FLgD_tudor PF13861.6 KKK22392.1 - 0.023 14.9 0.2 0.28 11.4 0.0 2.2 2 0 0 2 2 2 0 FlgD Tudor-like domain DUF2974 PF11187.8 KKK22392.1 - 0.032 13.8 0.8 0.62 9.6 0.8 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF2974) Hydrolase_4 PF12146.8 KKK22392.1 - 0.13 11.5 0.0 0.25 10.6 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Lipase_GDSL_2 PF13472.6 KKK22393.1 - 1.1e-11 45.4 2.0 3.3e-11 43.9 2.0 1.8 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KKK22393.1 - 5.2e-08 33.1 0.0 7.3e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.6 KKK22393.1 - 0.12 12.5 0.3 0.23 11.6 0.0 1.5 2 0 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family GST_C_3 PF14497.6 KKK22394.1 - 1.4e-08 34.8 0.0 2.8e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KKK22394.1 - 1.5e-08 34.7 0.0 2.5e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KKK22394.1 - 7.9e-07 29.0 0.1 1.5e-06 28.2 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glyco_tranf_2_3 PF13641.6 KKK22395.1 - 9.8e-18 64.9 0.0 1.6e-17 64.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 KKK22395.1 - 1.8e-05 24.3 0.0 4e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 KKK22395.1 - 0.00044 20.1 0.0 0.00074 19.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 RrnaAD PF00398.20 KKK22396.1 - 7.4e-67 225.2 0.0 9.6e-67 224.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 KKK22396.1 - 1.7e-05 25.4 0.0 3.1e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KKK22396.1 - 0.0023 18.5 0.0 0.0049 17.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KKK22396.1 - 0.0028 17.0 0.0 0.0043 16.4 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PCMT PF01135.19 KKK22396.1 - 0.0047 16.7 0.0 0.021 14.6 0.0 1.8 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) AAA_lid_4 PF17864.1 KKK22396.1 - 0.014 15.1 0.0 0.034 13.9 0.0 1.6 1 0 0 1 1 1 0 RuvB AAA lid domain Methyltransf_23 PF13489.6 KKK22396.1 - 0.04 13.8 0.0 0.062 13.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 KKK22396.1 - 0.1 12.2 0.0 0.3 10.6 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_12 PF08242.12 KKK22396.1 - 0.11 13.2 0.0 0.19 12.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain 2OG-FeII_Oxy_2 PF13532.6 KKK22397.1 - 1.7e-13 51.2 0.0 2.5e-13 50.7 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 KKK22397.1 - 0.0038 17.7 0.0 0.0074 16.8 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Abhydrolase_3 PF07859.13 KKK22398.1 - 2.6e-53 181.0 0.2 3.3e-53 180.7 0.2 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KKK22398.1 - 6.1e-14 51.7 0.0 8.3e-14 51.2 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Abhydrolase_2 PF02230.16 KKK22398.1 - 0.0014 18.5 0.0 0.0022 17.8 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 KKK22398.1 - 0.0026 17.3 0.0 0.0097 15.4 0.0 1.9 1 1 0 1 1 1 1 Prolyl oligopeptidase family Thioesterase PF00975.20 KKK22398.1 - 0.098 12.8 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Esterase PF00756.20 KKK22398.1 - 0.11 12.2 0.0 0.18 11.4 0.0 1.4 1 1 0 1 1 1 0 Putative esterase BAAT_C PF08840.11 KKK22398.1 - 0.13 12.1 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal MT-A70 PF05063.14 KKK22402.1 - 2.4e-24 86.1 0.2 4.6e-24 85.3 0.2 1.5 1 0 0 1 1 1 1 MT-A70 Peptidase_C12 PF01088.21 KKK22403.1 - 2.5e-46 158.1 0.0 3.2e-46 157.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 DcpS PF05652.12 KKK22404.1 - 3.3e-35 121.1 0.0 5.2e-35 120.4 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal DcpS_C PF11969.8 KKK22404.1 - 6.5e-31 107.2 0.0 1e-30 106.6 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding Nop53 PF07767.11 KKK22405.1 - 1.4e-103 347.4 32.0 1.4e-103 347.4 32.0 3.2 3 0 0 3 3 3 1 Nop53 (60S ribosomal biogenesis) RNase_H2_suC PF08615.11 KKK22405.1 - 3.4e-28 98.6 2.2 2.1e-27 96.0 0.0 3.3 3 1 0 3 3 3 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) RNase_T PF00929.24 KKK22405.1 - 5.5e-16 59.5 0.0 9.9e-15 55.5 0.0 2.6 2 1 0 2 2 2 1 Exonuclease Myb_Cef PF11831.8 KKK22406.1 - 2.1e-54 184.6 1.8 2.1e-54 184.6 1.8 3.2 4 0 0 4 4 4 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.31 KKK22406.1 - 4.6e-23 81.2 4.4 7.6e-11 42.0 0.7 3.6 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KKK22406.1 - 3e-20 72.2 2.7 3.6e-13 49.6 0.6 2.7 1 1 1 2 2 2 2 Myb-like DNA-binding domain Rap1_C PF11626.8 KKK22406.1 - 0.02 15.0 0.3 0.23 11.6 0.0 2.8 2 0 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain MOZ_SAS PF01853.18 KKK22407.1 - 9e-80 266.5 0.0 1.3e-79 266.0 0.0 1.3 1 0 0 1 1 1 1 MOZ/SAS family Tudor-knot PF11717.8 KKK22407.1 - 4.1e-22 77.8 0.0 8.7e-22 76.8 0.0 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain zf-MYST PF17772.1 KKK22407.1 - 1.7e-21 75.6 0.1 3.3e-21 74.6 0.1 1.5 1 0 0 1 1 1 1 MYST family zinc finger domain Acetyltransf_7 PF13508.7 KKK22407.1 - 0.0057 17.0 0.0 0.012 16.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KKK22407.1 - 0.011 15.9 0.0 0.027 14.7 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family F1F0-ATPsyn_F PF10791.9 KKK22409.1 - 4.2e-35 120.1 0.1 5e-35 119.9 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi ETC_C1_NDUFA4 PF04800.12 KKK22410.1 - 1.9e-36 124.2 1.3 2.8e-36 123.6 1.3 1.3 1 0 0 1 1 1 1 ETC complex I subunit conserved region Glyco_hydro_72 PF03198.14 KKK22412.1 - 1.3e-129 432.0 4.9 1.9e-129 431.5 4.9 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.13 KKK22412.1 - 1.8e-22 79.8 5.1 5.4e-22 78.3 5.1 1.9 1 0 0 1 1 1 1 X8 domain Glyco_hydro_2_C PF02836.17 KKK22412.1 - 0.029 13.5 0.3 0.066 12.3 0.3 1.7 1 1 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain Cellulase PF00150.18 KKK22412.1 - 0.048 13.1 0.3 0.11 11.9 0.2 1.6 1 1 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) Fungal_trans PF04082.18 KKK22413.1 - 1.9e-12 46.8 1.0 3.3e-12 46.0 1.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK22413.1 - 4.2e-05 23.6 15.3 9.3e-05 22.5 15.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2070 PF09843.9 KKK22414.1 - 2.5 6.3 4.1 3.3 5.9 4.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) PUF PF00806.19 KKK22415.1 - 1.6e-27 93.6 0.0 1.7e-05 24.2 0.0 6.1 6 0 0 6 6 6 5 Pumilio-family RNA binding repeat RRM_1 PF00076.22 KKK22415.1 - 2.8e-11 43.1 0.0 6.2e-11 42.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) YL1 PF05764.13 KKK22416.1 - 2.6e-62 211.1 28.4 2.6e-62 211.1 28.4 3.6 3 1 0 3 3 3 1 YL1 nuclear protein YL1_C PF08265.11 KKK22416.1 - 3.3e-12 45.9 0.5 9.9e-12 44.4 0.2 1.9 2 0 0 2 2 2 1 YL1 nuclear protein C-terminal domain TFIIS_C PF01096.18 KKK22417.1 - 5.3e-15 55.0 9.6 1.8e-14 53.3 2.7 3.1 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 KKK22417.1 - 0.0011 18.8 0.2 0.0011 18.8 0.2 2.8 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit TF_Zn_Ribbon PF08271.12 KKK22417.1 - 0.01 15.3 4.5 1.1 8.8 0.1 3.4 3 0 0 3 3 3 0 TFIIB zinc-binding Zn-ribbon_8 PF09723.10 KKK22417.1 - 0.024 14.8 2.5 3 8.0 0.3 2.6 2 1 0 2 2 2 0 Zinc ribbon domain DZR PF12773.7 KKK22417.1 - 0.033 14.2 6.3 1.8 8.6 6.3 2.5 1 1 0 1 1 1 0 Double zinc ribbon zf-IS66 PF13005.7 KKK22417.1 - 0.095 13.1 2.7 33 5.0 0.1 3.3 3 0 0 3 3 3 0 zinc-finger binding domain of transposase IS66 Lar_restr_allev PF14354.6 KKK22417.1 - 0.12 12.8 5.9 10 6.6 0.6 3.2 2 1 1 3 3 3 0 Restriction alleviation protein Lar Nudix_N_2 PF14803.6 KKK22417.1 - 0.19 11.6 6.3 0.31 11.0 2.2 2.7 2 1 0 2 2 2 0 Nudix N-terminal zinc_ribbon_2 PF13240.6 KKK22417.1 - 0.42 10.4 10.8 6.7 6.6 0.0 3.6 4 0 0 4 4 4 0 zinc-ribbon domain zf-ribbon_3 PF13248.6 KKK22417.1 - 0.72 9.3 9.1 14 5.2 0.0 3.6 4 0 0 4 4 4 0 zinc-ribbon domain OrfB_Zn_ribbon PF07282.11 KKK22417.1 - 4.5 7.3 6.5 5.1 7.1 0.2 2.6 2 2 0 2 2 2 0 Putative transposase DNA-binding domain HEAT_2 PF13646.6 KKK22418.1 - 1.8e-30 105.2 0.2 3.5e-14 52.9 0.1 3.4 2 2 2 4 4 4 3 HEAT repeats HEAT_PBS PF03130.16 KKK22418.1 - 7.7e-20 69.5 0.1 0.028 15.1 0.0 6.8 7 0 0 7 7 7 5 PBS lyase HEAT-like repeat HEAT PF02985.22 KKK22418.1 - 2.5e-08 33.5 1.6 2.5 8.6 0.0 6.6 7 0 0 7 7 7 1 HEAT repeat Cnd1 PF12717.7 KKK22418.1 - 0.003 17.6 0.0 6.6 6.8 0.0 3.2 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 KKK22418.1 - 0.0042 17.6 6.5 8.7 7.0 0.0 5.3 4 3 3 7 7 7 1 HEAT-like repeat Cohesin_HEAT PF12765.7 KKK22418.1 - 0.031 14.6 0.0 0.57 10.5 0.0 2.7 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion PUB_1 PF18486.1 KKK22418.1 - 0.1 12.5 0.7 0.48 10.3 0.2 2.4 2 0 0 2 2 2 0 PNGase/UBA- or UBX-containing domain RuvA_C PF07499.13 KKK22418.1 - 0.11 12.9 2.1 6.6 7.3 0.1 3.1 3 0 0 3 3 3 0 RuvA, C-terminal domain NUC153 PF08159.12 KKK22419.1 - 3.2e-15 55.6 5.7 4.5e-14 52.0 0.6 3.6 3 0 0 3 3 3 2 NUC153 domain PRK PF00485.18 KKK22420.1 - 1.8e-52 177.9 0.1 7.9e-52 175.9 0.1 1.9 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family UPRTase PF14681.6 KKK22420.1 - 1.9e-41 141.8 0.0 4.9e-41 140.5 0.0 1.6 2 0 0 2 2 2 1 Uracil phosphoribosyltransferase AAA_18 PF13238.6 KKK22420.1 - 4.1e-07 30.6 0.0 1.2e-06 29.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain CPT PF07931.12 KKK22420.1 - 3.7e-05 23.7 0.0 7.9e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_17 PF13207.6 KKK22420.1 - 0.0018 18.7 0.2 4.4 7.7 0.0 3.0 4 0 0 4 4 4 2 AAA domain Zeta_toxin PF06414.12 KKK22420.1 - 0.015 14.5 0.0 0.032 13.5 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_33 PF13671.6 KKK22420.1 - 0.016 15.4 0.0 0.031 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KKK22420.1 - 0.073 13.4 0.0 0.19 12.1 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain NB-ARC PF00931.22 KKK22420.1 - 0.13 11.5 0.0 0.26 10.5 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Cytidylate_kin PF02224.18 KKK22420.1 - 0.13 12.0 0.0 1.6 8.4 0.0 2.2 2 0 0 2 2 2 0 Cytidylate kinase AAA_5 PF07728.14 KKK22420.1 - 0.16 11.9 0.0 0.82 9.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) APS_kinase PF01583.20 KKK22420.1 - 0.18 11.7 0.1 1.1 9.1 0.1 2.1 2 0 0 2 2 2 0 Adenylylsulphate kinase CbiA PF01656.23 KKK22420.1 - 0.18 11.9 0.0 0.51 10.4 0.0 1.7 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain ABC_tran PF00005.27 KKK22420.1 - 0.25 11.9 0.8 1.8 9.1 0.2 2.2 2 0 0 2 2 2 0 ABC transporter CLTH PF10607.9 KKK22421.1 - 1.6e-29 102.7 0.0 2e-29 102.4 0.0 1.1 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 KKK22421.1 - 6.7e-08 32.2 0.0 1.2e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 LisH Nipped-B_C PF12830.7 KKK22422.1 - 2.1e-46 158.3 4.1 7.4e-45 153.2 0.5 3.4 3 1 0 3 3 3 1 Sister chromatid cohesion C-terminus Pyr_redox_2 PF07992.14 KKK22422.1 - 1e-42 146.4 0.0 1.6e-42 145.7 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Cohesin_HEAT PF12765.7 KKK22422.1 - 3.6e-12 46.3 2.8 1e-11 44.9 1.6 2.6 2 0 0 2 2 2 1 HEAT repeat associated with sister chromatid cohesion Pyr_redox PF00070.27 KKK22422.1 - 5.1e-10 39.8 0.0 7.2e-09 36.1 0.0 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase EF-hand_1 PF00036.32 KKK22422.1 - 2e-06 27.0 0.1 7.3e-06 25.2 0.1 2.1 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.6 KKK22422.1 - 2.9e-05 23.3 0.3 8.9e-05 21.8 0.3 1.9 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 KKK22422.1 - 4e-05 23.2 0.3 0.00022 20.9 0.3 2.4 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 KKK22422.1 - 4.9e-05 23.7 0.0 0.00031 21.1 0.0 2.5 1 0 0 1 1 1 1 EF-hand domain pair Cnd3 PF12719.7 KKK22422.1 - 0.00011 21.6 2.1 0.3 10.3 0.0 3.3 2 1 0 2 2 2 2 Nuclear condensing complex subunits, C-term domain Adaptin_N PF01602.20 KKK22422.1 - 0.00012 20.8 1.2 0.0014 17.3 0.7 2.8 2 1 0 2 2 2 1 Adaptin N terminal region Cnd1 PF12717.7 KKK22422.1 - 0.00036 20.6 1.2 0.0057 16.7 0.2 3.1 2 1 2 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KKK22422.1 - 0.0066 16.6 3.8 0.97 9.9 0.4 4.9 4 0 0 4 4 4 1 HEAT repeat Xpo1 PF08389.12 KKK22422.1 - 0.024 14.7 0.1 2.2 8.3 0.0 3.5 3 0 0 3 3 3 0 Exportin 1-like protein Fungal_trans PF04082.18 KKK22423.1 - 1.7e-18 66.7 0.1 3.4e-18 65.7 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK22423.1 - 6.7e-09 35.7 12.1 1.2e-08 35.0 12.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PspB PF06667.12 KKK22423.1 - 0.16 12.0 1.0 3.2 7.9 0.0 2.4 2 0 0 2 2 2 0 Phage shock protein B TMPIT PF07851.13 KKK22423.1 - 0.93 8.7 3.1 2.7 7.2 1.6 2.0 2 0 0 2 2 2 0 TMPIT-like protein IML1 PF12257.8 KKK22424.1 - 2.4e-111 371.4 0.0 3.3e-111 371.0 0.0 1.2 1 0 0 1 1 1 1 Vacuolar membrane-associated protein Iml1 DEP PF00610.21 KKK22424.1 - 2.6e-29 101.1 0.7 4.8e-29 100.2 0.7 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Glyco_hydro_31 PF01055.26 KKK22425.1 - 6e-109 365.1 1.9 8.1e-109 364.7 1.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 KKK22425.1 - 2.3e-18 66.2 0.1 1.7e-17 63.4 0.2 2.4 2 0 0 2 2 2 1 Galactose mutarotase-like FNIP_N PF14636.6 KKK22426.1 - 1.6e-28 100.6 0.1 1.6e-28 100.6 0.1 4.2 4 0 0 4 4 4 2 Folliculin-interacting protein N-terminus LPD22 PF18834.1 KKK22426.1 - 0.0099 16.1 0.4 0.032 14.4 0.4 1.9 1 0 0 1 1 1 1 Large polyvalent protein associated domain 22 eIF-1a PF01176.19 KKK22428.1 - 4.2e-22 77.7 0.0 5.9e-22 77.2 0.0 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 ERCC4 PF02732.15 KKK22429.1 - 2.1e-18 67.0 0.0 4.8e-18 65.9 0.0 1.7 1 0 0 1 1 1 1 ERCC4 domain HHH_5 PF14520.6 KKK22429.1 - 0.0018 18.8 0.0 0.0042 17.6 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain CNOT1_HEAT PF16418.5 KKK22429.1 - 0.077 13.1 0.1 3.2 7.8 0.0 3.0 3 0 0 3 3 3 0 CCR4-NOT transcription complex subunit 1 HEAT repeat Cytochrome_CBB3 PF13442.6 KKK22430.1 - 0.16 12.3 0.1 0.19 12.1 0.1 1.1 1 0 0 1 1 1 0 Cytochrome C oxidase, cbb3-type, subunit III fn3_2 PF16893.5 KKK22431.1 - 2.1e-38 130.4 0.1 4.2e-38 129.4 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III domain CHS5_N PF16892.5 KKK22431.1 - 4.7e-25 87.3 0.4 8.8e-25 86.4 0.4 1.5 1 0 0 1 1 1 1 Chitin biosynthesis protein CHS5 N-terminus PTCB-BRCT PF12738.7 KKK22431.1 - 4.9e-12 45.6 0.0 8.3e-12 44.9 0.0 1.4 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.26 KKK22431.1 - 4.3e-08 33.4 0.0 7.7e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain DUF3006 PF11213.8 KKK22431.1 - 0.00015 21.9 0.0 0.00041 20.5 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3006) BRCT_2 PF16589.5 KKK22431.1 - 0.00078 19.8 0.0 0.0016 18.8 0.0 1.5 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain fn3 PF00041.21 KKK22431.1 - 0.0021 18.4 1.0 0.0075 16.6 0.0 2.3 2 1 0 2 2 2 1 Fibronectin type III domain WH1 PF00568.23 KKK22432.1 - 2.1e-29 101.7 0.0 3.2e-29 101.1 0.0 1.2 1 0 0 1 1 1 1 WH1 domain Dioxygenase_C PF00775.21 KKK22439.1 - 1.6e-06 27.6 0.0 3.2e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Dioxygenase DNA_pol_A_exo1 PF01612.20 KKK22439.1 - 0.0012 18.6 0.0 0.0022 17.7 0.0 1.4 1 1 0 1 1 1 1 3'-5' exonuclease Pro-kuma_activ PF09286.11 KKK22440.1 - 9.4e-38 129.7 0.0 2.2e-37 128.5 0.0 1.6 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 KKK22440.1 - 7.2e-09 35.3 0.1 1.4e-08 34.4 0.1 1.4 1 0 0 1 1 1 1 Subtilase family AA_permease_2 PF13520.6 KKK22441.1 - 1.6e-56 192.0 49.7 1.9e-56 191.7 49.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KKK22441.1 - 1.1e-19 70.4 37.0 1.5e-19 69.9 37.0 1.2 1 0 0 1 1 1 1 Amino acid permease DUF3493 PF11998.8 KKK22441.1 - 0.027 14.6 2.2 0.083 13.1 0.0 2.8 3 0 0 3 3 3 0 Low psii accumulation1 / Rep27 Erg28 PF03694.13 KKK22441.1 - 0.057 13.8 1.5 0.62 10.5 0.3 2.8 2 0 0 2 2 2 0 Erg28 like protein PIG-P PF08510.12 KKK22442.1 - 1.8e-51 173.2 0.7 3.7e-51 172.1 0.7 1.6 1 0 0 1 1 1 1 PIG-P Striatin PF08232.12 KKK22442.1 - 2.4e-42 145.2 10.1 2.4e-42 145.2 10.1 2.5 2 0 0 2 2 2 1 Striatin family WD40 PF00400.32 KKK22442.1 - 1.1e-23 83.0 17.8 0.00029 21.6 0.0 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKK22442.1 - 0.0048 17.2 0.0 2.5 8.5 0.0 4.3 3 1 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KKK22442.1 - 0.0097 15.8 0.0 0.018 14.9 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 KKK22442.1 - 0.056 12.0 0.0 0.11 11.0 0.0 1.4 1 0 0 1 1 1 0 Cytochrome D1 heme domain DPM2 PF07297.12 KKK22442.1 - 6.1 7.2 8.8 16 5.9 8.8 1.6 1 0 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) Blt1 PF12754.7 KKK22443.1 - 2.3e-46 157.8 0.2 4.4e-46 156.9 0.1 1.5 2 0 0 2 2 2 1 Blt1 N-terminal domain Blt1_C PF17183.4 KKK22443.1 - 7.9e-24 83.0 0.5 7.9e-24 83.0 0.5 1.6 2 0 0 2 2 2 1 Get5 carboxyl domain Gcd10p PF04189.13 KKK22444.1 - 1.8e-121 404.9 0.0 2.3e-121 404.6 0.0 1.1 1 0 0 1 1 1 1 Gcd10p family P21-Arc PF04062.14 KKK22445.1 - 5.1e-62 209.0 0.0 1.6e-61 207.4 0.0 1.6 1 1 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit His_Phos_2 PF00328.22 KKK22446.1 - 4.4e-07 29.6 0.6 0.00039 19.9 0.0 2.9 1 1 1 2 2 2 1 Histidine phosphatase superfamily (branch 2) SR-25 PF10500.9 KKK22446.1 - 1.7 8.2 18.6 2.8 7.5 18.6 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Pro_isomerase PF00160.21 KKK22447.1 - 2.3e-38 131.9 0.0 4.8e-38 130.9 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD HSF_DNA-bind PF00447.17 KKK22448.1 - 8.1e-29 100.1 0.3 1.9e-28 98.9 0.3 1.7 1 0 0 1 1 1 1 HSF-type DNA-binding TYA PF01021.19 KKK22448.1 - 0.021 15.2 3.2 0.1 12.9 3.2 2.2 1 0 0 1 1 1 0 TYA transposon protein TMF_DNA_bd PF12329.8 KKK22448.1 - 0.021 14.8 2.4 0.23 11.5 0.1 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding TRAF_BIRC3_bd PF16673.5 KKK22448.1 - 0.037 13.8 0.9 0.1 12.4 0.9 1.7 1 0 0 1 1 1 0 TNF receptor-associated factor BIRC3 binding domain Ets PF00178.22 KKK22448.1 - 0.07 13.6 0.0 0.16 12.4 0.0 1.5 1 0 0 1 1 1 0 Ets-domain CENP-F_leu_zip PF10473.9 KKK22448.1 - 0.15 12.1 0.6 15 5.6 0.0 2.2 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 APG6_N PF17675.1 KKK22448.1 - 0.53 10.8 2.7 0.8 10.2 0.2 2.4 3 0 0 3 3 3 0 Apg6 coiled-coil region MRP-L28 PF09812.9 KKK22448.1 - 0.65 10.1 3.5 0.41 10.8 1.0 1.9 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L28 APC_u15 PF16636.5 KKK22448.1 - 2.9 8.4 4.9 12 6.4 0.1 3.1 3 0 0 3 3 3 0 Unstructured region on APC between APC_crr regions 5 and 6 Aldo_ket_red PF00248.21 KKK22449.1 - 1e-19 70.9 0.0 4.4e-19 68.8 0.0 1.9 1 1 0 1 1 1 1 Aldo/keto reductase family MINDY_DUB PF04424.13 KKK22450.1 - 8.9e-18 64.4 0.0 1.7e-17 63.5 0.0 1.4 1 0 0 1 1 1 1 MINDY deubiquitinase RSN1_7TM PF02714.15 KKK22451.1 - 7.1e-87 291.2 26.3 1.3e-86 290.4 18.5 2.5 3 0 0 3 3 3 2 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 KKK22451.1 - 2.2e-41 141.2 3.1 2.2e-41 141.2 3.1 2.5 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 KKK22451.1 - 6.6e-33 114.4 0.1 1.3e-32 113.4 0.1 1.5 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 KKK22451.1 - 3.8e-27 94.3 0.6 1.1e-26 92.8 0.6 1.7 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter Rep_fac_C PF08542.11 KKK22452.1 - 1.8e-17 63.5 0.0 4.9e-17 62.1 0.0 1.8 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.29 KKK22452.1 - 1.3e-16 61.2 0.0 2.3e-16 60.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 KKK22452.1 - 3.8e-12 46.3 0.1 2e-11 43.9 0.1 2.1 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.15 KKK22452.1 - 9.8e-11 41.9 0.0 1.6e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_assoc_2 PF16193.5 KKK22452.1 - 5.9e-07 29.7 0.0 3.3e-06 27.3 0.0 2.3 2 1 1 3 3 2 1 AAA C-terminal domain AAA_11 PF13086.6 KKK22452.1 - 1.4e-06 28.3 0.3 4.6e-05 23.3 0.0 2.2 1 1 1 2 2 2 1 AAA domain AAA_30 PF13604.6 KKK22452.1 - 1.7e-06 27.9 0.0 3.3e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KKK22452.1 - 2.1e-06 28.3 0.0 1.7e-05 25.3 0.0 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KKK22452.1 - 6.8e-06 26.4 0.2 4.7e-05 23.7 0.1 2.4 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.12 KKK22452.1 - 2.3e-05 24.2 0.0 7.7e-05 22.5 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KKK22452.1 - 2.3e-05 24.4 0.1 9.5e-05 22.4 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) DNA_pol3_delta PF06144.13 KKK22452.1 - 3.5e-05 23.6 0.0 7e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit DUF815 PF05673.13 KKK22452.1 - 3.5e-05 23.1 0.0 6.1e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_24 PF13479.6 KKK22452.1 - 4.6e-05 23.2 0.0 7.4e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KKK22452.1 - 0.00012 22.4 0.1 0.00044 20.6 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_3 PF07726.11 KKK22452.1 - 0.00016 21.5 0.2 0.00051 19.9 0.1 2.0 2 1 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 KKK22452.1 - 0.00038 20.5 0.0 0.002 18.2 0.0 2.0 1 1 1 2 2 2 1 AAA domain PhoH PF02562.16 KKK22452.1 - 0.00082 18.9 0.0 0.44 10.0 0.0 2.3 2 0 0 2 2 2 2 PhoH-like protein ResIII PF04851.15 KKK22452.1 - 0.0028 17.7 0.0 0.096 12.7 0.0 2.2 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KKK22452.1 - 0.0036 17.1 0.1 0.023 14.4 0.0 2.0 1 1 1 2 2 2 1 DEAD/DEAH box helicase AAA_18 PF13238.6 KKK22452.1 - 0.0066 17.0 0.0 0.011 16.3 0.0 1.6 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 KKK22452.1 - 0.0088 15.4 0.1 0.11 11.8 0.1 2.5 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 KKK22452.1 - 0.01 16.1 0.0 0.02 15.1 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KKK22452.1 - 0.014 14.9 0.0 0.037 13.5 0.0 1.7 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF2075 PF09848.9 KKK22452.1 - 0.015 14.5 0.0 0.025 13.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) TniB PF05621.11 KKK22452.1 - 0.041 13.3 0.1 0.42 10.0 0.1 2.2 1 1 0 1 1 1 0 Bacterial TniB protein IstB_IS21 PF01695.17 KKK22452.1 - 0.044 13.5 0.0 0.32 10.7 0.0 2.1 1 1 0 1 1 1 0 IstB-like ATP binding protein NACHT PF05729.12 KKK22452.1 - 0.054 13.4 0.0 0.098 12.6 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_25 PF13481.6 KKK22452.1 - 0.056 13.0 0.0 0.18 11.4 0.0 1.7 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KKK22452.1 - 0.072 13.5 0.0 0.16 12.3 0.0 1.7 1 0 0 1 1 1 0 RNA helicase ATPase_2 PF01637.18 KKK22452.1 - 0.079 12.9 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Viral_helicase1 PF01443.18 KKK22452.1 - 0.14 11.9 0.0 0.36 10.5 0.0 1.7 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase DUF3431 PF11913.8 KKK22453.1 - 6.9e-86 287.5 0.5 6.9e-86 287.5 0.5 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3431) SR-25 PF10500.9 KKK22453.1 - 0.015 15.0 4.6 0.02 14.5 4.6 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Macoilin PF09726.9 KKK22453.1 - 0.15 10.6 0.9 0.16 10.5 0.9 1.1 1 0 0 1 1 1 0 Macoilin family FSA_C PF10479.9 KKK22453.1 - 0.22 9.6 2.0 0.29 9.2 2.0 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus zf-C2H2 PF00096.26 KKK22465.1 - 0.00021 21.5 18.4 1.4 9.5 1.1 5.2 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KKK22465.1 - 0.0094 16.7 19.4 0.8 10.7 0.8 5.2 4 1 0 4 4 4 3 C2H2-type zinc finger zf-met PF12874.7 KKK22465.1 - 0.13 12.7 1.4 7 7.2 0.6 3.0 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KKK22465.1 - 0.62 10.4 6.2 5.3 7.5 0.6 3.3 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding MUG113 PF13455.6 KKK22470.1 - 1.3e-27 96.2 0.0 2.7e-27 95.3 0.0 1.5 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 T5orf172 PF10544.9 KKK22470.1 - 5.3e-26 91.1 0.0 1.5e-25 89.7 0.0 1.8 1 0 0 1 1 1 1 T5orf172 domain TOM6p PF15184.6 KKK22470.1 - 0.051 13.4 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial import receptor subunit TOM6 homolog DUF1631 PF07793.11 KKK22470.1 - 0.29 9.5 3.4 0.38 9.1 3.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) Importin_rep PF18773.1 KKK22471.1 - 4e-06 26.4 0.0 9.2e-06 25.3 0.0 1.7 1 0 0 1 1 1 1 Importin 13 repeat Importin_rep_3 PF18806.1 KKK22471.1 - 4.7e-06 26.6 0.0 1.6e-05 24.8 0.0 2.0 1 0 0 1 1 1 1 Importin 13 repeat IBN_N PF03810.19 KKK22471.1 - 9.2e-06 25.5 0.1 3.7e-05 23.6 0.1 2.1 1 0 0 1 1 1 1 Importin-beta N-terminal domain Creatinase_N_2 PF16189.5 KKK22472.1 - 4.1e-54 183.0 0.0 2.3e-52 177.3 0.0 2.3 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain Peptidase_M24 PF00557.24 KKK22472.1 - 6e-44 150.2 0.0 8.5e-44 149.7 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Peptidase_M24_C PF16188.5 KKK22472.1 - 8.1e-23 80.3 0.4 1.8e-22 79.1 0.4 1.6 1 0 0 1 1 1 1 C-terminal region of peptidase_M24 Creatinase_N PF01321.18 KKK22472.1 - 1.2e-18 68.0 0.0 1.2e-15 58.3 0.0 2.5 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain Sec8_exocyst PF04048.14 KKK22473.1 - 2.5e-49 166.8 4.6 4.4e-49 166.0 3.1 2.2 2 0 0 2 2 2 1 Sec8 exocyst complex component specific domain Vps54_N PF10475.9 KKK22473.1 - 2.6e-08 33.5 2.2 4.8e-08 32.6 2.2 1.3 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex Zw10 PF06248.13 KKK22473.1 - 2e-05 23.4 0.3 3.5e-05 22.6 0.3 1.3 1 0 0 1 1 1 1 Centromere/kinetochore Zw10 Sec5 PF15469.6 KKK22473.1 - 0.00067 19.5 1.5 0.0015 18.4 1.5 1.5 1 0 0 1 1 1 1 Exocyst complex component Sec5 Dor1 PF04124.12 KKK22473.1 - 0.011 14.4 5.9 0.019 13.7 4.8 1.9 2 0 0 2 2 2 0 Dor1-like family Occludin_ELL PF07303.13 KKK22473.1 - 0.047 14.4 0.3 0.37 11.5 0.5 2.5 2 0 0 2 2 2 0 Occludin homology domain FliJ PF02050.16 KKK22473.1 - 0.13 12.4 6.1 1.8 8.8 0.1 2.7 2 1 0 2 2 2 0 Flagellar FliJ protein Spc7 PF08317.11 KKK22473.1 - 0.14 11.0 2.2 0.27 10.1 2.2 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein DPBB_1 PF03330.18 KKK22474.1 - 9.7e-09 35.4 0.1 9.7e-09 35.4 0.1 2.7 3 1 0 3 3 3 1 Lytic transglycolase Pollen_allerg_1 PF01357.21 KKK22474.1 - 0.00026 20.9 0.3 0.00089 19.2 0.3 1.9 1 0 0 1 1 1 1 Pollen allergen HLH PF00010.26 KKK22475.1 - 1.2e-12 47.5 2.0 1.2e-12 47.5 2.0 1.8 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain SAC3_GANP PF03399.16 KKK22476.1 - 3.1e-101 338.6 0.3 4.1e-101 338.2 0.3 1.1 1 0 0 1 1 1 1 SAC3/GANP family CN_hydrolase PF00795.22 KKK22476.1 - 1.6e-11 44.1 0.0 3.1e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase CSN8_PSD8_EIF3K PF10075.9 KKK22476.1 - 0.0096 15.9 0.0 0.027 14.4 0.0 1.7 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family DUF2841 PF11001.8 KKK22477.1 - 1.5e-49 167.2 0.5 2.3e-49 166.5 0.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) RRM_1 PF00076.22 KKK22478.1 - 9.1e-14 51.0 0.0 1.4e-13 50.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KKK22478.1 - 0.0028 17.5 0.0 0.0039 17.0 0.0 1.2 1 0 0 1 1 1 1 Occluded RNA-recognition motif Ribosomal_S16 PF00886.19 KKK22480.1 - 2.7e-24 85.0 0.1 3.6e-24 84.6 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S16 UBD PF16455.5 KKK22480.1 - 0.18 12.1 0.0 0.26 11.6 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin-binding domain YjeF_N PF03853.15 KKK22481.1 - 6.1e-24 84.8 0.0 1.2e-23 83.9 0.0 1.4 1 1 1 2 2 2 1 YjeF-related protein N-terminus PUL PF08324.11 KKK22482.1 - 2.4e-73 246.8 0.7 3.7e-73 246.2 0.7 1.3 1 0 0 1 1 1 1 PUL domain PFU PF09070.11 KKK22482.1 - 1.4e-44 151.0 0.1 3e-44 149.9 0.1 1.6 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.32 KKK22482.1 - 5.1e-28 96.7 11.9 2.4e-07 31.3 0.0 7.8 7 0 0 7 7 7 6 WD domain, G-beta repeat BBS2_Mid PF14783.6 KKK22482.1 - 0.014 15.4 0.0 0.97 9.5 0.0 3.0 2 1 1 3 3 3 0 Ciliary BBSome complex subunit 2, middle region CH PF00307.31 KKK22483.1 - 6.5e-44 148.6 0.5 7.6e-22 77.6 0.0 2.6 2 0 0 2 2 2 2 Calponin homology (CH) domain EFhand_Ca_insen PF08726.10 KKK22483.1 - 1.4e-28 98.7 0.1 4.4e-28 97.2 0.1 1.9 1 0 0 1 1 1 1 Ca2+ insensitive EF hand RRM_1 PF00076.22 KKK22483.1 - 1.2e-17 63.5 0.0 2.8e-17 62.3 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CAMSAP_CH PF11971.8 KKK22483.1 - 2.3e-08 33.7 0.1 8.7e-07 28.7 0.0 2.7 2 0 0 2 2 2 1 CAMSAP CH domain FoP_duplication PF13865.6 KKK22483.1 - 2.2e-07 31.3 7.7 2.2e-07 31.3 7.7 3.4 4 0 0 4 4 4 1 C-terminal duplication domain of Friend of PRMT1 EF-hand_6 PF13405.6 KKK22483.1 - 0.00043 20.0 0.0 0.0024 17.7 0.0 2.4 1 0 0 1 1 1 1 EF-hand domain EF-hand_1 PF00036.32 KKK22483.1 - 0.0052 16.2 0.1 0.056 13.0 0.0 2.6 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 KKK22483.1 - 0.014 15.2 0.0 0.061 13.2 0.0 2.2 2 0 0 2 2 2 0 EF-hand domain pair Aldo_ket_red PF00248.21 KKK22484.1 - 1.7e-36 126.0 0.0 3.9e-34 118.2 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family WD40 PF00400.32 KKK22485.1 - 1.6e-22 79.4 9.0 3.2e-07 30.9 0.0 6.5 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKK22485.1 - 1e-07 32.1 0.3 0.24 11.7 0.0 4.0 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KKK22485.1 - 0.0037 16.3 0.1 0.23 10.4 0.0 2.5 2 0 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Me-amine-dh_H PF06433.11 KKK22485.1 - 0.0075 15.2 0.0 0.52 9.1 0.0 2.1 2 0 0 2 2 2 2 Methylamine dehydrogenase heavy chain (MADH) Nup160 PF11715.8 KKK22485.1 - 0.012 14.3 1.0 1 7.9 0.1 2.5 1 1 1 2 2 2 0 Nucleoporin Nup120/160 dsrm PF00035.26 KKK22485.1 - 0.15 12.8 0.0 0.39 11.5 0.0 1.7 1 0 0 1 1 1 0 Double-stranded RNA binding motif ArgJ PF01960.18 KKK22486.1 - 2.4e-148 493.9 0.1 2.7e-148 493.7 0.1 1.0 1 0 0 1 1 1 1 ArgJ family Ldh_1_C PF02866.18 KKK22486.1 - 0.12 12.3 0.2 0.23 11.4 0.2 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, alpha/beta C-terminal domain Pkinase PF00069.25 KKK22487.1 - 5.6e-19 68.5 0.0 1.5e-18 67.1 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK22487.1 - 8.1e-18 64.6 0.0 1.7e-17 63.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase DUF812 PF05667.11 KKK22487.1 - 0.0052 15.7 1.9 0.007 15.3 1.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) RIO1 PF01163.22 KKK22487.1 - 0.049 13.2 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 RIO1 family HAUS5 PF14817.6 KKK22487.1 - 0.2 10.4 8.7 0.29 9.8 8.7 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 Exonuc_VII_L PF02601.15 KKK22487.1 - 0.43 10.1 4.9 0.76 9.3 4.9 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Nup88 PF10168.9 KKK22487.1 - 2.9 5.6 5.8 4.3 5.0 5.8 1.1 1 0 0 1 1 1 0 Nuclear pore component Cyclin_N PF00134.23 KKK22488.1 - 0.0008 19.2 0.0 0.0044 16.8 0.0 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain TFIIB PF00382.19 KKK22488.1 - 0.0058 16.7 0.0 0.28 11.3 0.0 2.4 2 0 0 2 2 2 1 Transcription factor TFIIB repeat Autophagy_N PF03986.13 KKK22489.1 - 5.8e-47 159.1 0.1 1.2e-46 158.1 0.1 1.6 1 0 0 1 1 1 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_C PF10381.9 KKK22489.1 - 8.7e-16 57.1 0.4 1.4e-15 56.5 0.4 1.3 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal Autophagy_act_C PF03987.15 KKK22489.1 - 5.3e-13 49.4 0.1 9.5e-13 48.5 0.1 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain DUF1471 PF07338.13 KKK22489.1 - 0.14 12.2 0.6 0.31 11.1 0.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1471) CDC27 PF09507.10 KKK22489.1 - 0.28 10.5 5.4 0.46 9.8 5.4 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 PBP1_TM PF14812.6 KKK22489.1 - 3.2 8.2 8.0 0.22 11.9 2.7 1.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF2457 PF10446.9 KKK22489.1 - 5.4 6.0 13.0 8.6 5.4 13.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nop14 PF04147.12 KKK22489.1 - 5.7 5.0 10.6 8.1 4.5 10.6 1.2 1 0 0 1 1 1 0 Nop14-like family FUN14 PF04930.15 KKK22490.1 - 2.3e-10 40.7 0.5 4.5e-10 39.8 0.5 1.5 1 0 0 1 1 1 1 FUN14 family DUF543 PF04418.12 KKK22490.1 - 0.17 11.9 3.8 0.39 10.7 2.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF543) ORC2 PF04084.14 KKK22491.1 - 1.2e-119 399.1 0.0 1.5e-119 398.9 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 2 ORC6 PF05460.13 KKK22491.1 - 5.2 6.2 13.7 3.9 6.7 11.4 2.0 1 1 2 3 3 3 0 Origin recognition complex subunit 6 (ORC6) Ribosomal_S27 PF01599.19 KKK22492.1 - 0.16 12.2 1.1 0.55 10.4 0.0 2.2 2 0 0 2 2 2 0 Ribosomal protein S27a SecY PF00344.20 KKK22493.1 - 4.3e-73 246.2 6.8 5.3e-73 245.9 6.8 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 KKK22493.1 - 2.2e-17 62.6 0.3 6e-17 61.2 0.3 1.8 1 0 0 1 1 1 1 Plug domain of Sec61p Promethin PF16015.5 KKK22494.1 - 5.7e-09 35.8 17.2 5.7e-09 35.8 17.2 2.1 1 1 1 2 2 2 1 Promethin SSFA2_C PF14723.6 KKK22494.1 - 0.19 11.6 3.6 0.29 11.0 3.6 1.2 1 0 0 1 1 1 0 Sperm-specific antigen 2 C-terminus DUF4707 PF15806.5 KKK22494.1 - 0.65 8.9 4.1 0.89 8.4 4.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4707) Stevor PF17410.2 KKK22494.1 - 4.1 6.9 6.5 7.4 6.0 6.5 1.3 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame SOR_SNZ PF01680.17 KKK22495.1 - 5.6e-108 359.5 3.1 7.9e-108 359.0 3.1 1.2 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.14 KKK22495.1 - 7.4e-10 38.6 2.9 3.4e-06 26.5 0.1 2.4 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG TetR_C_27 PF17935.1 KKK22495.1 - 0.00088 19.3 0.0 0.0024 17.9 0.0 1.7 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain Dus PF01207.17 KKK22495.1 - 0.002 17.3 1.2 0.83 8.7 0.0 2.5 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 KKK22495.1 - 0.0042 16.6 0.1 0.051 13.0 0.0 2.4 2 1 0 2 2 2 1 Histidine biosynthesis protein IGPS PF00218.21 KKK22495.1 - 0.0065 15.7 0.0 0.53 9.4 0.0 2.4 2 0 0 2 2 2 1 Indole-3-glycerol phosphate synthase NanE PF04131.14 KKK22495.1 - 0.025 13.8 0.9 0.29 10.3 0.0 2.5 2 1 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase TMP-TENI PF02581.17 KKK22495.1 - 0.086 12.2 1.3 1.2 8.4 0.0 3.0 3 0 0 3 3 3 0 Thiamine monophosphate synthase NMO PF03060.15 KKK22495.1 - 0.21 11.0 6.5 0.34 10.2 0.1 2.3 2 0 0 2 2 2 0 Nitronate monooxygenase NUDIX PF00293.28 KKK22496.1 - 9.8e-07 28.9 0.0 1.6e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain NUDIX PF00293.28 KKK22497.1 - 2e-17 63.5 0.0 3.1e-17 62.9 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain HAD_2 PF13419.6 KKK22498.1 - 2.5e-20 73.3 0.0 3.6e-20 72.8 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KKK22498.1 - 2.7e-07 31.1 0.2 1.8e-06 28.4 0.2 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KKK22498.1 - 0.0018 18.3 0.0 0.0029 17.6 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 KKK22498.1 - 0.014 15.8 0.0 0.021 15.2 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Rit1_C PF17184.4 KKK22499.1 - 1.4e-103 346.1 0.0 1.7e-103 345.8 0.0 1.1 1 0 0 1 1 1 1 Rit1 N-terminal domain Init_tRNA_PT PF04179.12 KKK22499.1 - 2.8e-33 114.5 0.0 6.5e-33 113.3 0.0 1.7 1 0 0 1 1 1 1 Rit1 DUSP-like domain Glycos_transf_2 PF00535.26 KKK22501.1 - 3.1e-23 82.4 0.0 3.8e-22 78.9 0.0 2.3 1 1 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KKK22501.1 - 8.9e-06 25.7 0.0 0.01 15.8 0.0 2.9 3 0 0 3 3 3 2 Glycosyltransferase like family 2 EST1_DNA_bind PF10373.9 KKK22502.1 - 1.8e-07 31.0 0.1 7e-06 25.7 0.0 2.4 2 0 0 2 2 2 2 Est1 DNA/RNA binding domain zf-C3HC4_3 PF13920.6 KKK22503.1 - 7.1e-13 48.2 6.1 1e-12 47.7 6.1 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KKK22503.1 - 1.7e-06 27.8 6.9 2.7e-06 27.1 6.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KKK22503.1 - 7.3e-06 26.2 7.4 1.2e-05 25.6 7.4 1.3 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 KKK22503.1 - 1.5e-05 24.8 6.6 2.7e-05 23.9 6.6 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KKK22503.1 - 0.00015 21.6 5.9 0.00024 21.0 5.9 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KKK22503.1 - 0.013 15.5 3.5 0.013 15.5 3.5 1.9 1 1 1 2 2 2 0 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KKK22503.1 - 0.021 14.7 10.1 0.056 13.3 10.1 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KKK22503.1 - 0.08 12.7 1.6 0.33 10.8 0.9 2.2 2 0 0 2 2 2 0 RING-like zinc finger zf-C3HC4_4 PF15227.6 KKK22503.1 - 0.19 11.9 6.8 0.38 10.9 6.8 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 KKK22503.1 - 0.23 11.3 5.7 0.42 10.5 5.7 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Mucin PF01456.17 KKK22521.1 - 2.1 8.3 10.4 4.1 7.4 10.4 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein RabGAP-TBC PF00566.18 KKK22522.1 - 4.3e-13 49.4 5.7 6.6e-13 48.8 5.7 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain RP-C_C PF11800.8 KKK22522.1 - 0.15 12.1 0.1 0.21 11.7 0.1 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region Herpes_UL6 PF01763.16 KKK22552.1 - 0.0014 17.3 1.9 0.0018 16.9 1.9 1.1 1 0 0 1 1 1 1 Herpesvirus UL6 like Rootletin PF15035.6 KKK22552.1 - 0.0017 18.4 5.5 0.0025 17.9 5.5 1.3 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion Med4 PF10018.9 KKK22552.1 - 0.0066 16.1 4.0 0.017 14.8 4.0 1.7 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 Tropomyosin_1 PF12718.7 KKK22552.1 - 0.02 15.0 5.9 0.02 15.0 5.9 1.6 2 0 0 2 2 2 0 Tropomyosin like DUF3450 PF11932.8 KKK22552.1 - 0.032 13.5 7.8 0.047 13.0 7.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF3452 PF11934.8 KKK22552.1 - 0.067 12.7 0.2 1.9 8.0 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3452) YabA PF06156.13 KKK22552.1 - 0.077 13.6 6.6 0.096 13.3 3.8 2.1 2 0 0 2 2 2 0 Initiation control protein YabA bZIP_1 PF00170.21 KKK22552.1 - 0.086 12.9 7.7 0.18 11.9 6.0 2.3 1 1 1 2 2 2 0 bZIP transcription factor DUF3886 PF13025.6 KKK22552.1 - 0.17 12.1 8.8 0.38 11.0 8.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3886) SlyX PF04102.12 KKK22552.1 - 0.2 12.3 8.6 0.49 11.0 8.6 1.8 1 0 0 1 1 1 0 SlyX DUF5595 PF18077.1 KKK22552.1 - 0.65 10.1 2.9 1.3 9.2 2.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5595) 7tm_7 PF08395.12 KKK22552.1 - 0.71 9.0 2.6 1.1 8.3 2.6 1.2 1 0 0 1 1 1 0 7tm Chemosensory receptor CAGE1 PF15066.6 KKK22552.1 - 0.72 8.5 12.1 1 8.0 12.1 1.1 1 0 0 1 1 1 0 Cancer-associated gene protein 1 family DivIC PF04977.15 KKK22552.1 - 0.94 9.3 11.0 1.9 8.3 10.5 1.7 1 1 0 1 1 1 0 Septum formation initiator Sas6_CC PF18594.1 KKK22552.1 - 1.1 9.1 3.9 7 6.5 3.9 2.3 1 1 0 1 1 1 0 Sas6/XLF/XRCC4 coiled-coil domain TERB2 PF15101.6 KKK22552.1 - 1.4 9.0 4.9 2.7 8.0 4.9 1.4 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF5320 PF17253.2 KKK22552.1 - 2.2 9.4 4.3 4.8 8.3 4.3 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5320) KfrA_N PF11740.8 KKK22552.1 - 2.5 8.8 7.9 5.5 7.7 7.9 1.5 1 0 0 1 1 1 0 Plasmid replication region DNA-binding N-term Anp1 PF03452.14 KKK22553.1 - 1.9e-106 355.3 0.0 2.4e-106 355.0 0.0 1.1 1 0 0 1 1 1 1 Anp1 Asn_synthase PF00733.21 KKK22554.1 - 7.3e-94 315.3 0.5 1.1e-54 186.5 0.0 2.1 1 1 1 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 KKK22554.1 - 1.6e-35 121.7 0.0 2.7e-35 121.0 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 KKK22554.1 - 7.3e-25 87.7 0.0 1.3e-24 86.9 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 KKK22554.1 - 5.2e-09 35.9 0.0 1e-08 34.9 0.0 1.4 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.17 KKK22554.1 - 0.00076 18.7 0.0 0.0014 17.8 0.0 1.5 1 1 0 1 1 1 1 NAD synthase QueC PF06508.13 KKK22554.1 - 0.21 11.1 0.0 0.41 10.1 0.0 1.4 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC Porin_3 PF01459.22 KKK22555.1 - 8.3e-74 248.4 4.3 1.9e-59 201.4 1.4 2.0 2 0 0 2 2 2 2 Eukaryotic porin VasI PF11319.8 KKK22555.1 - 0.22 11.2 0.1 1.9 8.1 0.0 2.3 3 0 0 3 3 3 0 Type VI secretion system VasI, EvfG, VC_A0118 YCII PF03795.14 KKK22557.1 - 0.067 13.6 0.0 0.073 13.5 0.0 1.1 1 0 0 1 1 1 0 YCII-related domain AMP-binding PF00501.28 KKK22558.1 - 9.3e-85 284.8 0.0 1.2e-84 284.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KKK22558.1 - 3.2e-16 60.1 0.0 1.3e-15 58.1 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain GH3 PF03321.13 KKK22558.1 - 0.0002 20.4 0.0 0.00042 19.3 0.0 1.4 2 0 0 2 2 2 1 GH3 auxin-responsive promoter G-patch PF01585.23 KKK22559.1 - 1.5e-10 40.8 1.7 3.1e-10 39.8 1.7 1.5 1 0 0 1 1 1 1 G-patch domain RRM_1 PF00076.22 KKK22559.1 - 0.00017 21.4 0.2 0.00049 19.9 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) G-patch_2 PF12656.7 KKK22559.1 - 0.0077 16.3 0.3 0.027 14.6 0.3 1.9 1 0 0 1 1 1 1 G-patch domain DUF5559 PF17714.1 KKK22559.1 - 0.12 12.3 1.4 0.3 11.0 1.4 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5559) UQ_con PF00179.26 KKK22560.1 - 1.8e-49 167.0 0.0 2.1e-49 166.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KKK22560.1 - 2.8e-05 23.8 0.0 3.2e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 KKK22560.1 - 0.059 13.7 0.9 0.07 13.4 0.9 1.5 1 1 0 1 1 1 0 RWD domain Diphthamide_syn PF01866.17 KKK22561.1 - 3.6e-88 295.9 0.0 4.5e-88 295.6 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein TFIIE-A_C PF11521.8 KKK22561.1 - 4.4 7.7 11.2 13 6.1 0.0 2.7 3 0 0 3 3 3 0 C-terminal general transcription factor TFIIE alpha Fe-ADH PF00465.19 KKK22562.1 - 8e-29 100.6 0.0 9e-29 100.4 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Cutinase PF01083.22 KKK22563.1 - 2.9e-49 167.4 0.0 3.3e-49 167.3 0.0 1.0 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 KKK22563.1 - 0.00027 20.6 0.0 0.00045 19.8 0.0 1.3 1 0 0 1 1 1 1 PE-PPE domain VirJ PF06057.11 KKK22563.1 - 0.0065 16.4 0.0 0.0098 15.8 0.0 1.2 1 0 0 1 1 1 1 Bacterial virulence protein (VirJ) RraA-like PF03737.15 KKK22563.1 - 0.024 14.8 0.0 0.037 14.2 0.0 1.3 1 0 0 1 1 1 0 Aldolase/RraA DUF2974 PF11187.8 KKK22563.1 - 0.05 13.1 0.0 0.063 12.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) CS PF04969.16 KKK22564.1 - 9.3e-19 68.2 0.3 1.7e-18 67.4 0.0 1.6 2 0 0 2 2 2 1 CS domain Zn_clus PF00172.18 KKK22566.1 - 4.2e-10 39.6 10.1 7.5e-10 38.8 10.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Clusterin PF01093.17 KKK22566.1 - 0.98 8.4 3.9 1.2 8.1 3.9 1.1 1 0 0 1 1 1 0 Clusterin ADH_N PF08240.12 KKK22588.1 - 3.7e-34 116.9 1.0 3.7e-34 116.9 1.0 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KKK22588.1 - 1.3e-23 83.4 0.3 2.1e-23 82.7 0.3 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KKK22588.1 - 3.6e-09 36.4 0.1 6.4e-09 35.6 0.1 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 KKK22588.1 - 0.0002 22.4 0.0 0.00042 21.4 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KKK22588.1 - 0.0014 18.0 0.6 0.0023 17.3 0.6 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.14 KKK22588.1 - 0.0096 15.5 0.0 0.016 14.8 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Methyltransf_25 PF13649.6 KKK22588.1 - 0.025 15.3 0.0 0.053 14.2 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Pyr_redox_2 PF07992.14 KKK22588.1 - 0.031 13.5 0.4 0.051 12.8 0.1 1.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 KKK22588.1 - 0.11 11.8 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PrmA PF06325.13 KKK22588.1 - 0.18 11.2 0.1 0.26 10.6 0.1 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Pyr_redox_3 PF13738.6 KKK22588.1 - 0.25 10.5 1.2 0.61 9.3 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Ras PF00071.22 KKK22589.1 - 5e-38 130.2 0.0 9.3e-38 129.4 0.0 1.4 1 1 0 1 1 1 1 Ras family Roc PF08477.13 KKK22589.1 - 2.1e-26 92.5 0.0 3.1e-26 91.9 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKK22589.1 - 1.9e-11 43.7 0.0 2.3e-10 40.2 0.0 2.0 2 0 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KKK22589.1 - 0.004 17.2 0.0 0.0065 16.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KKK22589.1 - 0.0088 15.4 0.0 0.012 15.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 KKK22589.1 - 0.019 14.9 0.0 0.082 12.8 0.0 2.0 3 0 0 3 3 3 0 RsgA GTPase AAA_16 PF13191.6 KKK22589.1 - 0.034 14.5 0.0 0.42 11.0 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_33 PF13671.6 KKK22589.1 - 0.076 13.2 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain SRPRB PF09439.10 KKK22589.1 - 0.11 11.9 0.0 0.19 11.1 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit ABC_tran PF00005.27 KKK22589.1 - 0.12 12.9 0.0 0.24 11.9 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_7 PF12775.7 KKK22589.1 - 0.14 11.6 0.0 0.24 10.9 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region PduV-EutP PF10662.9 KKK22589.1 - 0.14 11.9 0.0 7.9 6.2 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation FAD-oxidase_C PF02913.19 KKK22590.1 - 2.3e-60 204.3 0.1 3.7e-60 203.7 0.1 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 KKK22590.1 - 3.2e-35 120.9 0.0 7.8e-35 119.6 0.0 1.7 1 0 0 1 1 1 1 FAD binding domain NIF PF03031.18 KKK22594.1 - 2.7e-54 183.1 0.1 3.7e-54 182.7 0.1 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase NP1-WLL PF11733.8 KKK22594.1 - 0.43 10.3 3.0 0.8 9.4 3.0 1.4 1 0 0 1 1 1 0 Non-capsid protein NP1 LRR_4 PF12799.7 KKK22595.1 - 2.5e-20 72.2 30.9 4.2e-05 23.8 0.2 4.4 1 1 5 6 6 6 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KKK22595.1 - 5.3e-13 48.5 10.5 0.00061 19.5 2.7 4.1 4 0 0 4 4 4 3 Leucine rich repeat LRR_9 PF14580.6 KKK22595.1 - 4.8e-08 32.7 12.5 2.6e-06 27.0 2.6 2.4 1 1 2 3 3 3 2 Leucine-rich repeat LRR_1 PF00560.33 KKK22595.1 - 0.4 11.4 12.9 3.6 8.5 0.8 5.5 5 2 0 5 5 5 0 Leucine Rich Repeat LRR_6 PF13516.6 KKK22595.1 - 0.5 10.6 10.3 0.33 11.1 0.6 4.6 7 0 0 7 7 7 0 Leucine Rich repeat PLN_propep PF16485.5 KKK22606.1 - 0.029 14.1 0.1 0.029 14.1 0.1 2.2 3 0 0 3 3 3 0 Protealysin propeptide Nop16 PF09420.10 KKK22607.1 - 1e-69 234.8 11.3 1.1e-69 234.6 11.3 1.0 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 Myb_DNA-binding PF00249.31 KKK22607.1 - 0.071 13.3 0.1 0.12 12.5 0.1 1.4 1 0 0 1 1 1 0 Myb-like DNA-binding domain Coilin_N PF15862.5 KKK22607.1 - 4.6 7.1 7.4 0.14 11.9 1.1 1.6 2 0 0 2 2 2 0 Coilin N-terminus Zip PF02535.22 KKK22608.1 - 2.4e-62 211.1 4.5 5.5e-62 209.9 4.5 1.5 1 1 0 1 1 1 1 ZIP Zinc transporter Anp1 PF03452.14 KKK22609.1 - 5.6e-107 357.0 0.0 6.6e-107 356.8 0.0 1.0 1 0 0 1 1 1 1 Anp1 Glycos_transf_2 PF00535.26 KKK22609.1 - 0.0093 15.8 0.0 0.017 15.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Mito_carr PF00153.27 KKK22610.1 - 5.5e-55 183.3 0.4 3.9e-19 68.4 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein bZIP_1 PF00170.21 KKK22611.1 - 3.8e-08 33.3 12.9 8e-08 32.3 12.9 1.5 1 0 0 1 1 1 1 bZIP transcription factor PAP1 PF08601.10 KKK22611.1 - 0.00025 20.9 0.1 0.00025 20.9 0.1 2.6 2 1 0 2 2 1 1 Transcription factor PAP1 bZIP_2 PF07716.15 KKK22611.1 - 0.0018 18.3 16.6 0.0025 17.9 14.9 1.9 1 1 1 2 2 2 1 Basic region leucine zipper NRBF2 PF08961.10 KKK22611.1 - 0.015 14.9 0.5 0.025 14.2 0.5 1.4 1 0 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator PSI_PsaF PF02507.15 KKK22611.1 - 0.019 14.8 1.1 0.031 14.1 1.1 1.3 1 0 0 1 1 1 0 Photosystem I reaction centre subunit III V_ATPase_I PF01496.19 KKK22611.1 - 0.022 12.7 0.2 0.025 12.5 0.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family UPF0242 PF06785.11 KKK22611.1 - 0.022 14.9 3.6 0.035 14.2 3.6 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus TMF_TATA_bd PF12325.8 KKK22611.1 - 0.055 13.7 5.0 0.11 12.7 5.0 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding bZIP_Maf PF03131.17 KKK22611.1 - 0.085 13.4 9.8 0.15 12.6 9.8 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor SHE3 PF17078.5 KKK22611.1 - 0.16 11.7 4.9 0.26 11.0 4.9 1.3 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 DUF5094 PF17015.5 KKK22611.1 - 0.29 11.2 3.7 0.56 10.3 3.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5094) Phosducin PF02114.16 KKK22612.1 - 6.2e-06 25.3 0.0 6.8e-06 25.2 0.0 1.1 1 0 0 1 1 1 1 Phosducin Kelch_4 PF13418.6 KKK22613.1 - 6.3e-33 112.5 10.0 1.4e-08 34.6 0.9 6.8 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_3 PF13415.6 KKK22613.1 - 5.4e-31 106.3 9.5 4e-06 27.0 0.2 5.8 5 0 0 5 5 5 5 Galactose oxidase, central domain Kelch_1 PF01344.25 KKK22613.1 - 2.7e-27 94.1 0.4 1.7e-11 43.5 0.1 6.1 6 0 0 6 6 6 4 Kelch motif Kelch_5 PF13854.6 KKK22613.1 - 3.2e-27 94.0 5.2 3.7e-07 30.0 0.1 6.5 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.6 KKK22613.1 - 1.2e-26 92.0 7.9 7.4e-11 41.9 0.6 6.4 4 1 2 6 6 6 5 Kelch motif Pkinase PF00069.25 KKK22613.1 - 4.8e-25 88.4 0.0 1e-24 87.4 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Kelch_2 PF07646.15 KKK22613.1 - 4.2e-20 70.9 7.2 2.5e-08 33.6 0.4 6.5 6 0 0 6 6 6 4 Kelch motif Pkinase_Tyr PF07714.17 KKK22613.1 - 1.3e-12 47.5 0.0 2.3e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KKK22613.1 - 5.8e-08 31.9 0.0 5.8e-08 31.9 0.0 2.9 2 1 0 2 2 1 1 Fungal protein kinase Spc7 PF08317.11 KKK22613.1 - 0.00049 19.1 18.6 0.00049 19.1 18.6 5.2 1 1 4 5 5 5 1 Spc7 kinetochore protein TPR_MLP1_2 PF07926.12 KKK22613.1 - 0.0065 16.5 10.6 0.0065 16.5 10.6 8.7 6 2 1 8 8 8 2 TPR/MLP1/MLP2-like protein APH PF01636.23 KKK22613.1 - 0.0098 15.8 0.0 0.0098 15.8 0.0 4.3 4 1 1 5 5 3 1 Phosphotransferase enzyme family DUF5398 PF17376.2 KKK22613.1 - 0.16 12.6 3.6 0.24 12.0 1.3 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5398) FHA PF00498.26 KKK22617.1 - 5.8e-17 61.8 0.0 1.2e-16 60.7 0.0 1.6 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KKK22617.1 - 0.00022 21.5 0.0 0.00058 20.1 0.0 1.7 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain CENP-Q PF13094.6 KKK22617.1 - 0.01 16.0 8.6 0.01 16.0 8.6 3.4 2 1 1 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit YhfZ_C PF14503.6 KKK22617.1 - 0.03 13.9 0.0 0.057 12.9 0.0 1.4 1 0 0 1 1 1 0 YhfZ C-terminal domain Cbl_N PF02262.16 KKK22617.1 - 0.061 13.3 3.3 1.2 9.1 0.5 2.4 2 0 0 2 2 2 0 CBL proto-oncogene N-terminal domain 1 Cep57_MT_bd PF06657.13 KKK22617.1 - 1.1 9.7 11.8 0.56 10.7 7.0 2.6 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 DUF2203 PF09969.9 KKK22617.1 - 6.4 7.5 13.9 4.5 8.0 0.1 3.5 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2203) Romo1 PF10247.9 KKK22618.1 - 2.8e-28 98.1 15.7 3.6e-28 97.7 15.7 1.1 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 Tim17 PF02466.19 KKK22618.1 - 0.0012 19.3 2.6 0.0013 19.0 2.6 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family RTA1 PF04479.13 KKK22619.1 - 2e-48 164.8 3.9 2e-48 164.8 3.9 2.0 1 1 1 2 2 2 2 RTA1 like protein DUF4239 PF14023.6 KKK22619.1 - 0.078 12.7 1.4 0.15 11.7 1.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) DUF3439 PF11921.8 KKK22620.1 - 0.0004 20.4 6.6 0.025 14.5 1.4 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF3439) zf-RING_2 PF13639.6 KKK22621.1 - 4.8e-13 49.2 5.4 7.5e-13 48.6 5.4 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KKK22621.1 - 2.2e-09 36.9 2.2 2.2e-09 36.9 2.2 1.8 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KKK22621.1 - 5.2e-09 35.8 4.4 8.3e-09 35.2 4.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PA PF02225.22 KKK22621.1 - 6.5e-09 35.7 0.0 1.4e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 PA domain zf-rbx1 PF12678.7 KKK22621.1 - 8.3e-09 35.6 2.4 1.6e-08 34.7 2.4 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KKK22621.1 - 1.4e-08 34.5 3.6 2.2e-08 33.8 3.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KKK22621.1 - 1.9e-07 30.9 2.9 3e-07 30.3 2.9 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KKK22621.1 - 4.7e-06 26.4 3.1 7.1e-06 25.8 3.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KKK22621.1 - 6.4e-06 26.1 1.9 1.2e-05 25.2 0.4 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 KKK22621.1 - 0.00056 19.9 0.7 0.0011 19.0 0.7 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 KKK22621.1 - 0.0019 18.0 2.7 0.0033 17.2 2.7 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KKK22621.1 - 0.045 13.9 2.8 0.11 12.7 2.8 1.7 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.8 KKK22621.1 - 0.045 13.9 2.4 0.12 12.6 2.4 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 KKK22621.1 - 0.046 13.3 2.7 0.082 12.5 2.7 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type RINGv PF12906.7 KKK22621.1 - 0.35 11.0 4.1 0.67 10.1 4.1 1.5 1 0 0 1 1 1 0 RING-variant domain PHD PF00628.29 KKK22621.1 - 0.46 10.4 2.8 0.83 9.6 2.8 1.5 1 0 0 1 1 1 0 PHD-finger zf-RING_4 PF14570.6 KKK22621.1 - 0.63 9.9 3.1 1.1 9.1 3.1 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING-like PF08746.11 KKK22621.1 - 1.6 9.1 3.6 3 8.2 3.6 1.5 1 0 0 1 1 1 0 RING-like domain Histone PF00125.24 KKK22621.1 - 3.5 8.0 13.8 0.24 11.8 2.9 2.6 2 0 0 2 2 2 0 Core histone H2A/H2B/H3/H4 Rpp20 PF12328.8 KKK22623.1 - 8.6e-53 178.0 3.2 1.2e-52 177.5 3.2 1.2 1 0 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.21 KKK22623.1 - 6.9e-19 67.4 0.4 1.2e-18 66.7 0.4 1.4 1 0 0 1 1 1 1 Alba DUF5567 PF17722.1 KKK22623.1 - 0.0019 18.1 0.6 0.0025 17.7 0.6 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5567) NUDE_C PF04880.13 KKK22624.1 - 2.3 8.7 5.9 2.5 8.5 5.9 1.2 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region LRR_8 PF13855.6 KKK22625.1 - 6.8e-11 41.8 4.4 2.9e-08 33.3 2.1 2.5 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 KKK22625.1 - 1.9e-06 28.1 8.4 0.002 18.5 0.0 3.3 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KKK22625.1 - 0.16 12.6 8.5 4.2 8.3 0.0 4.8 5 0 0 5 5 5 0 Leucine Rich Repeat DUF3292 PF11696.8 KKK22625.1 - 0.36 9.2 1.1 0.52 8.6 1.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) Raptor_N PF14538.6 KKK22626.1 - 1.7e-65 219.5 0.0 3.2e-65 218.6 0.0 1.5 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain WD40 PF00400.32 KKK22626.1 - 1.4e-06 28.9 5.7 0.61 11.1 0.0 6.5 5 1 0 5 5 5 1 WD domain, G-beta repeat Kdo PF06293.14 KKK22626.1 - 2.3e-06 27.1 0.4 4.7e-06 26.1 0.4 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family BBS2_Mid PF14783.6 KKK22626.1 - 0.0043 17.1 0.1 3.5 7.7 0.1 2.9 1 1 1 2 2 2 2 Ciliary BBSome complex subunit 2, middle region RIO1 PF01163.22 KKK22626.1 - 0.0098 15.5 0.0 0.019 14.6 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Atx10homo_assoc PF09759.9 KKK22626.1 - 0.046 13.8 0.0 0.11 12.5 0.0 1.7 1 0 0 1 1 1 0 Spinocerebellar ataxia type 10 protein domain APH PF01636.23 KKK22626.1 - 0.095 12.6 0.2 0.39 10.6 0.1 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase PF00069.25 KKK22626.1 - 0.19 11.1 0.1 0.36 10.2 0.1 1.3 1 0 0 1 1 1 0 Protein kinase domain DnaJ_C PF01556.18 KKK22627.1 - 4e-39 134.1 0.1 5.4e-39 133.6 0.1 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KKK22627.1 - 3.5e-26 91.1 1.2 5.8e-26 90.4 1.2 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KKK22627.1 - 8e-16 58.2 17.9 1.4e-15 57.4 17.9 1.4 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.19 KKK22627.1 - 0.3 11.1 8.8 0.21 11.6 2.1 2.4 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF2614 PF11023.8 KKK22627.1 - 3.7 7.7 6.9 8.1 6.6 1.0 2.2 1 1 1 2 2 2 0 Zinc-ribbon containing domain zinc-ribbons_6 PF07191.12 KKK22627.1 - 6.5 6.8 6.5 9.6 6.3 1.5 2.2 1 1 1 2 2 2 0 zinc-ribbons dCMP_cyt_deam_1 PF00383.23 KKK22628.1 - 2.4e-18 65.9 0.0 3.6e-18 65.3 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KKK22628.1 - 6.9e-16 58.2 0.0 9.5e-16 57.8 0.0 1.1 1 0 0 1 1 1 1 MafB19-like deaminase SNAD4 PF18750.1 KKK22628.1 - 0.0006 19.9 0.0 0.0017 18.4 0.0 1.7 2 0 0 2 2 2 1 Secreted Novel AID/APOBEC-like Deaminase 4 NAD2 PF18782.1 KKK22628.1 - 0.00089 19.4 0.0 0.0087 16.2 0.0 2.0 1 1 0 1 1 1 1 Novel AID APOBEC clade 2 Bd3614-deam PF14439.6 KKK22628.1 - 0.0012 18.9 2.0 0.073 13.1 0.8 2.2 1 1 1 2 2 2 1 Bd3614-like deaminase APOBEC2 PF18772.1 KKK22628.1 - 0.0014 18.7 0.1 0.023 14.7 0.1 2.0 1 1 0 1 1 1 1 APOBEC2 NAD1 PF18778.1 KKK22628.1 - 0.0033 17.5 0.1 0.027 14.6 0.1 2.0 1 1 0 1 1 1 1 Novel AID APOBEC clade 1 APOBEC_N PF08210.11 KKK22628.1 - 0.0047 16.8 0.1 0.011 15.6 0.1 1.6 1 1 0 1 1 1 1 APOBEC-like N-terminal domain XOO_2897-deam PF14440.6 KKK22628.1 - 0.075 13.2 0.1 0.14 12.3 0.0 1.6 2 0 0 2 2 2 0 Xanthomonas XOO_2897-like deaminase APOBEC3 PF18771.1 KKK22628.1 - 0.11 12.6 0.0 0.43 10.7 0.0 1.8 1 1 1 2 2 2 0 APOBEC3 WD40 PF00400.32 KKK22629.1 - 0.0047 17.7 0.2 6.9 7.7 0.0 3.6 3 0 0 3 3 3 1 WD domain, G-beta repeat Biopterin_H PF00351.21 KKK22629.1 - 0.092 11.8 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Biopterin-dependent aromatic amino acid hydroxylase Vps53_N PF04100.12 KKK22630.1 - 9.8e-110 367.1 3.7 1.1e-109 366.9 1.7 2.0 2 0 0 2 2 2 1 Vps53-like, N-terminal Vps54_N PF10475.9 KKK22630.1 - 2.8e-08 33.4 7.6 5.2e-08 32.5 7.6 1.4 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex DUF2451 PF10474.9 KKK22630.1 - 6.8e-07 29.3 1.1 1.7e-06 28.0 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function C-terminus (DUF2451) COG2 PF06148.11 KKK22630.1 - 4.6e-06 26.8 2.8 1.6e-05 25.0 2.1 2.3 2 0 0 2 2 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Spc7 PF08317.11 KKK22630.1 - 8.3e-05 21.6 6.7 0.00017 20.6 6.7 1.4 1 0 0 1 1 1 1 Spc7 kinetochore protein RINT1_TIP1 PF04437.13 KKK22630.1 - 0.00056 18.9 0.5 0.00056 18.9 0.5 3.1 2 1 0 2 2 2 1 RINT-1 / TIP-1 family APG6_N PF17675.1 KKK22630.1 - 0.01 16.3 5.1 0.046 14.2 5.1 2.2 1 0 0 1 1 1 0 Apg6 coiled-coil region Tnp_22_trimer PF17489.2 KKK22630.1 - 0.011 15.6 0.9 0.25 11.3 0.8 2.7 2 0 0 2 2 2 0 L1 transposable element trimerization domain XhlA PF10779.9 KKK22630.1 - 0.013 15.7 3.1 0.045 14.0 3.1 2.0 1 0 0 1 1 1 0 Haemolysin XhlA Baculo_PEP_C PF04513.12 KKK22630.1 - 0.025 14.6 5.0 0.047 13.7 2.9 2.6 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Sec8_exocyst PF04048.14 KKK22630.1 - 0.044 13.7 5.5 0.022 14.6 2.7 2.0 2 0 0 2 2 1 0 Sec8 exocyst complex component specific domain NBD94 PF16830.5 KKK22630.1 - 0.047 14.1 2.2 0.14 12.5 2.2 1.8 1 0 0 1 1 1 0 Nucleotide-Binding Domain 94 of RH Sigma70_ner PF04546.13 KKK22630.1 - 0.047 13.6 7.0 0.1 12.5 4.3 2.4 2 0 0 2 2 2 0 Sigma-70, non-essential region DUF5339 PF17274.2 KKK22630.1 - 0.061 14.2 3.4 3.1 8.7 1.3 3.4 2 1 1 3 3 2 0 Family of unknown function (DUF5339) Syntaxin_2 PF14523.6 KKK22630.1 - 0.13 12.6 4.4 0.36 11.2 2.6 2.9 2 0 0 2 2 2 0 Syntaxin-like protein YvfG PF09628.10 KKK22630.1 - 0.14 12.5 0.2 3.5 8.1 0.0 2.8 2 0 0 2 2 2 0 YvfG protein FapA PF03961.13 KKK22630.1 - 0.15 10.7 1.2 0.26 9.8 1.2 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF1515 PF07439.11 KKK22630.1 - 0.15 12.1 2.2 0.44 10.6 2.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) DUF16 PF01519.16 KKK22630.1 - 0.18 12.3 2.9 1.3 9.5 2.6 2.6 2 0 0 2 2 2 0 Protein of unknown function DUF16 DUF5082 PF16888.5 KKK22630.1 - 0.32 11.3 8.1 3.7 7.8 1.3 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF5082) Sec34 PF04136.15 KKK22630.1 - 0.45 10.4 6.4 1.1 9.2 4.5 2.7 2 1 0 2 2 2 0 Sec34-like family DUF1664 PF07889.12 KKK22630.1 - 0.5 10.4 4.7 0.68 10.0 2.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) BRE1 PF08647.11 KKK22630.1 - 0.93 9.6 7.5 1.4 9.1 5.8 2.3 2 0 0 2 2 1 0 BRE1 E3 ubiquitin ligase BLOC1_2 PF10046.9 KKK22630.1 - 1.5 9.2 8.4 0.34 11.3 2.8 2.9 3 0 0 3 3 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 URO-D PF01208.17 KKK22631.1 - 1.6e-126 422.2 0.0 2.8e-124 414.8 0.0 2.0 1 1 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) Ribosomal_L10 PF00466.20 KKK22632.1 - 1.5e-24 86.0 0.6 3.1e-24 85.0 0.3 1.6 2 0 0 2 2 2 1 Ribosomal protein L10 RL10P_insert PF17777.1 KKK22632.1 - 3.1e-23 81.5 0.1 7.6e-23 80.3 0.0 1.7 2 0 0 2 2 2 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_60s PF00428.19 KKK22632.1 - 4.4e-23 81.7 3.5 4.4e-23 81.7 3.5 2.1 2 0 0 2 2 2 1 60s Acidic ribosomal protein PH PF00169.29 KKK22633.1 - 3.1e-07 30.9 0.0 4.5e-06 27.1 0.0 2.4 2 0 0 2 2 2 1 PH domain PH_9 PF15410.6 KKK22633.1 - 0.0032 17.8 0.0 0.01 16.2 0.0 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain NTF2 PF02136.20 KKK22635.1 - 1.2e-07 32.3 0.0 3.4e-07 30.8 0.0 1.8 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain TAP_C PF03943.13 KKK22635.1 - 1.2e-06 28.1 2.3 1.2e-06 28.1 2.3 1.9 2 0 0 2 2 2 1 TAP C-terminal domain LRR_9 PF14580.6 KKK22635.1 - 2.1e-06 27.3 0.0 3.5e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 KKK22635.1 - 2.4e-05 24.6 7.7 0.0015 18.9 1.0 2.6 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) RRM_9 PF18444.1 KKK22635.1 - 0.00015 21.5 0.0 0.00045 20.0 0.0 1.9 1 1 0 1 1 1 1 RNA recognition motif LRR_8 PF13855.6 KKK22635.1 - 0.00075 19.2 0.1 0.0018 18.0 0.1 1.7 1 0 0 1 1 1 1 Leucine rich repeat LRR_6 PF13516.6 KKK22635.1 - 0.011 15.7 1.1 6.9 7.0 0.2 3.4 3 0 0 3 3 3 0 Leucine Rich repeat LRR_1 PF00560.33 KKK22635.1 - 0.11 13.2 0.1 36 5.4 0.0 2.9 2 0 0 2 2 2 0 Leucine Rich Repeat AlgF PF11182.8 KKK22635.1 - 0.11 12.3 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 Alginate O-acetyl transferase AlgF COPIIcoated_ERV PF07970.12 KKK22636.1 - 1.8e-84 283.0 0.0 3.7e-84 282.0 0.0 1.5 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 KKK22636.1 - 9.1e-30 102.9 0.0 2.3e-29 101.6 0.0 1.7 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) G-gamma PF00631.22 KKK22637.1 - 1.9e-24 85.4 0.0 2.2e-24 85.2 0.0 1.1 1 0 0 1 1 1 1 GGL domain DUF3220 PF11516.8 KKK22637.1 - 0.071 13.3 0.0 0.097 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3120) Rdx PF10262.9 KKK22639.1 - 2.9e-31 107.5 0.0 3.9e-31 107.0 0.0 1.2 1 0 0 1 1 1 1 Rdx family Serglycin PF04360.12 KKK22639.1 - 0.017 15.0 0.2 0.027 14.4 0.2 1.3 1 0 0 1 1 1 0 Serglycin TCRP1 PF14944.6 KKK22639.1 - 0.026 14.5 0.2 0.034 14.1 0.2 1.2 1 0 0 1 1 1 0 Tongue Cancer Chemotherapy Resistant Protein 1 PDEase_I PF00233.19 KKK22640.1 - 1e-69 234.9 0.0 1.4e-69 234.4 0.0 1.2 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase HD PF01966.22 KKK22640.1 - 0.053 13.8 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 HD domain Acetyltransf_1 PF00583.25 KKK22641.1 - 2.5e-08 34.2 0.0 3.6e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KKK22641.1 - 3.8e-07 30.1 0.0 6.3e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KKK22641.1 - 1.8e-05 25.1 0.0 2.5e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KKK22641.1 - 3.1e-05 23.9 0.0 5.3e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 KKK22641.1 - 0.035 14.2 0.1 0.078 13.1 0.1 1.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain MFS_1 PF07690.16 KKK22642.1 - 7.5e-22 77.7 52.1 7.5e-20 71.1 41.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily PCI PF01399.27 KKK22643.1 - 1.8e-10 41.3 3.4 6.6e-10 39.4 0.0 3.4 3 1 0 3 3 3 1 PCI domain Vps4_C PF09336.10 KKK22643.1 - 0.069 13.2 0.4 5.7 7.0 0.1 2.7 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain RNA_pol_Rpb6 PF01192.22 KKK22644.1 - 2.5e-17 62.5 0.3 4.7e-17 61.7 0.1 1.6 2 0 0 2 2 2 1 RNA polymerase Rpb6 zf-C2H2 PF00096.26 KKK22645.1 - 2.8e-29 99.9 63.0 5.1e-05 23.5 0.4 11.3 10 2 1 11 11 11 10 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KKK22645.1 - 3e-17 61.8 61.4 0.029 15.2 0.3 11.4 11 0 0 11 11 11 7 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KKK22645.1 - 1.5e-12 47.4 54.5 0.00073 19.8 0.5 10.9 11 0 0 11 11 11 6 Zinc-finger double domain FOXP-CC PF16159.5 KKK22645.1 - 8.6e-06 26.3 32.9 0.16 12.6 0.1 9.1 6 2 3 9 9 9 3 FOXP coiled-coil domain zf-C2H2_jaz PF12171.8 KKK22645.1 - 4.2e-05 23.7 16.3 15 6.0 0.1 8.6 10 0 0 10 10 10 1 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 KKK22645.1 - 0.00046 20.4 24.4 0.38 11.1 1.2 5.3 3 2 3 6 6 6 4 C2H2-type zinc ribbon zf-C2H2_3rep PF18868.1 KKK22645.1 - 0.0029 18.3 19.5 0.89 10.2 0.1 4.8 1 1 1 4 4 4 3 Zinc finger C2H2-type, 3 repeats zf-C2H2_11 PF16622.5 KKK22645.1 - 0.25 11.1 14.5 5.9 6.8 1.3 5.1 5 0 0 5 5 5 0 zinc-finger C2H2-type GAGA PF09237.11 KKK22645.1 - 0.38 10.6 4.8 0.36 10.7 1.7 2.6 2 0 0 2 2 2 0 GAGA factor zf_Hakai PF18408.1 KKK22645.1 - 4.5 7.1 19.0 15 5.4 0.1 6.0 5 0 0 5 5 5 0 C2H2 Hakai zinc finger domain Sulfate_transp PF00916.20 KKK22646.1 - 9.9e-109 363.6 21.3 1.3e-108 363.1 21.3 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 KKK22646.1 - 5.6e-08 32.4 0.0 1.1e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 KKK22646.1 - 0.00015 22.1 3.2 0.00015 22.1 3.2 3.4 2 1 1 3 3 3 2 Molybdate transporter of MFS superfamily SNN_transmemb PF09049.10 KKK22646.1 - 1.9 8.5 8.7 0.082 12.9 1.2 2.7 2 0 0 2 2 2 0 Stannin transmembrane Ribosomal_L12 PF00542.19 KKK22655.1 - 6.2e-20 71.3 10.5 7.9e-19 67.8 8.9 2.2 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 KKK22655.1 - 6.8e-14 51.3 1.9 6.8e-14 51.3 1.9 2.8 3 1 0 3 3 3 1 Ribosomal protein L7/L12 dimerisation domain GHMP_kinases_C PF08544.13 KKK22655.1 - 0.034 14.5 3.1 7 7.1 0.5 3.3 2 2 1 3 3 3 0 GHMP kinases C terminal SpoVIF PF14069.6 KKK22655.1 - 0.038 13.8 2.8 0.052 13.3 1.0 2.1 2 1 0 2 2 2 0 Stage VI sporulation protein F HisG_C PF08029.11 KKK22655.1 - 0.048 13.8 0.1 0.13 12.4 0.1 1.9 1 0 0 1 1 1 0 HisG, C-terminal domain FliG_N PF14842.6 KKK22655.1 - 0.053 14.1 1.2 0.081 13.5 0.4 1.7 2 0 0 2 2 2 0 FliG N-terminal domain Methyltransf_34 PF11312.8 KKK22655.1 - 0.13 11.5 0.0 0.15 11.3 0.0 1.1 1 0 0 1 1 1 0 Putative SAM-dependent methyltransferase Alpha-amylase PF00128.24 KKK22656.1 - 2.8e-65 221.1 1.2 3.7e-65 220.7 1.2 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.11 KKK22656.1 - 1e-33 115.4 0.1 2.1e-33 114.4 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) Homeobox_KN PF05920.11 KKK22657.1 - 2.2e-21 75.5 0.3 2.2e-21 75.5 0.3 2.1 2 0 0 2 2 2 1 Homeobox KN domain Homeodomain PF00046.29 KKK22657.1 - 2.7e-07 30.3 0.1 4.9e-07 29.5 0.1 1.4 1 0 0 1 1 1 1 Homeodomain AA_permease_2 PF13520.6 KKK22658.1 - 1.1e-54 185.9 51.3 1.4e-54 185.5 51.3 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KKK22658.1 - 8.5e-23 80.7 46.4 1.2e-22 80.2 46.4 1.0 1 0 0 1 1 1 1 Amino acid permease APH PF01636.23 KKK22659.1 - 1.9e-12 47.6 0.0 1.2e-11 45.0 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family DUF5041 PF16444.5 KKK22659.1 - 0.037 14.3 0.0 0.063 13.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5041) Glyco_hydro_47 PF01532.20 KKK22660.1 - 4.4e-188 625.8 0.0 5.1e-188 625.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Glyco_hydro_127 PF07944.12 KKK22660.1 - 0.027 13.0 0.0 2 6.8 0.0 2.1 2 0 0 2 2 2 0 Beta-L-arabinofuranosidase, GH127 Phage_holin_2_1 PF04971.12 KKK22661.1 - 0.015 15.2 0.3 0.015 15.2 0.3 2.5 4 0 0 4 4 4 0 Bacteriophage P21 holin S FA_desaturase PF00487.24 KKK22661.1 - 5.9 6.6 9.3 3 7.6 4.7 2.1 2 0 0 2 2 2 0 Fatty acid desaturase Med20 PF08612.11 KKK22662.1 - 3.9e-95 317.5 0.0 4.5e-95 317.3 0.0 1.0 1 0 0 1 1 1 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex EF-hand_1 PF00036.32 KKK22663.1 - 1.3e-41 137.0 11.6 7.8e-10 37.6 0.9 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KKK22663.1 - 3.6e-36 123.4 5.3 3.9e-19 68.9 2.2 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 KKK22663.1 - 1.9e-34 117.3 11.5 2.4e-15 56.1 0.6 4.0 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 KKK22663.1 - 3.8e-30 101.2 8.5 7.1e-09 34.9 0.1 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 KKK22663.1 - 6.8e-26 88.6 9.8 4.7e-06 25.9 0.1 4.2 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 KKK22663.1 - 1.4e-16 60.5 0.4 2.3e-09 37.4 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 KKK22663.1 - 6.8e-10 38.8 1.6 0.00078 19.4 0.3 2.1 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 KKK22663.1 - 5.9e-09 36.2 0.2 0.0016 18.7 0.1 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.13 KKK22663.1 - 1e-06 28.6 0.1 0.008 16.2 0.0 3.0 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.10 KKK22663.1 - 6.4e-06 26.2 1.6 2.3e-05 24.4 0.2 2.3 2 1 0 2 2 2 1 Ca2+ insensitive EF hand EF-hand_11 PF08976.11 KKK22663.1 - 9.4e-05 23.2 0.2 0.0025 18.6 0.1 2.0 1 1 1 2 2 2 1 EF-hand domain TerB PF05099.13 KKK22663.1 - 0.00013 21.9 0.3 0.35 10.8 0.0 2.2 1 1 1 2 2 2 2 Tellurite resistance protein TerB Caleosin PF05042.13 KKK22663.1 - 0.00059 19.8 1.6 0.52 10.2 0.0 3.5 1 1 3 4 4 4 1 Caleosin related protein RNA_pol_Rpb4 PF03874.16 KKK22663.1 - 0.00062 20.1 0.7 0.66 10.3 0.1 2.6 2 1 1 3 3 3 2 RNA polymerase Rpb4 Dockerin_1 PF00404.18 KKK22663.1 - 0.0053 16.9 7.0 0.38 11.0 0.8 2.9 1 1 2 3 3 3 2 Dockerin type I domain DUF5580 PF17743.1 KKK22663.1 - 0.0057 15.3 0.0 0.0058 15.2 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5580) SurA_N_2 PF13623.6 KKK22663.1 - 0.0084 16.0 0.7 0.32 10.9 0.1 2.2 1 1 1 2 2 2 1 SurA N-terminal domain EF-hand_14 PF17959.1 KKK22663.1 - 0.012 16.0 0.5 6.2 7.2 0.1 2.4 1 1 1 2 2 2 0 EF-hand domain Poly_export PF02563.16 KKK22663.1 - 0.023 14.9 0.0 0.18 12.0 0.0 2.5 2 1 0 2 2 2 0 Polysaccharide biosynthesis/export protein RuvA_C PF07499.13 KKK22663.1 - 0.058 13.9 0.1 8.5 6.9 0.0 3.0 3 0 0 3 3 3 0 RuvA, C-terminal domain dCache_2 PF08269.11 KKK22663.1 - 0.061 12.5 0.1 1 8.5 0.1 2.1 1 1 1 2 2 2 0 Cache domain MotA_activ PF09114.10 KKK22663.1 - 0.061 13.5 0.3 0.91 9.7 0.0 2.3 1 1 0 2 2 2 0 Transcription factor MotA, activation domain DUF4497 PF14924.6 KKK22663.1 - 0.092 13.2 0.0 8.7 6.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4497) RloB PF13707.6 KKK22663.1 - 0.11 12.7 1.3 0.72 10.0 0.2 2.1 1 1 1 2 2 2 0 RloB-like protein DUF5132 PF17195.4 KKK22663.1 - 0.16 12.1 0.5 21 5.3 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF5132) CDC37_N PF03234.14 KKK22665.1 - 2.2e-48 164.4 4.1 2.2e-48 164.4 4.1 3.1 3 1 0 3 3 3 1 Cdc37 N terminal kinase binding CDC37_M PF08565.11 KKK22665.1 - 6.6e-43 145.4 0.9 1.7e-42 144.1 0.2 2.0 2 0 0 2 2 2 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.10 KKK22665.1 - 8.1e-34 115.7 3.8 8.1e-34 115.7 3.8 2.0 2 0 0 2 2 2 1 Cdc37 C terminal domain DUF4007 PF13182.6 KKK22665.1 - 0.022 13.9 0.0 0.053 12.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4007) Cytochrom_B562 PF07361.11 KKK22665.1 - 0.34 11.6 5.7 0.78 10.4 0.1 3.1 3 1 0 3 3 3 0 Cytochrome b562 Ribosomal_L12 PF00542.19 KKK22665.1 - 0.66 10.4 5.3 0.51 10.7 2.4 2.4 2 1 0 2 2 2 0 Ribosomal protein L7/L12 C-terminal domain DUF1682 PF07946.14 KKK22666.1 - 3.5e-111 371.5 4.8 4.1e-111 371.3 4.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) ABC_membrane PF00664.23 KKK22667.1 - 3.6e-49 167.9 8.7 4.6e-49 167.5 8.7 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 KKK22667.1 - 3.2e-35 121.6 0.0 8.2e-35 120.3 0.0 1.7 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KKK22667.1 - 0.00048 19.6 0.8 0.027 13.9 0.9 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KKK22667.1 - 0.013 15.3 0.0 0.035 13.8 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 KKK22667.1 - 0.02 15.2 0.1 0.12 12.7 0.1 2.1 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KKK22667.1 - 0.022 15.2 2.1 0.052 13.9 0.1 2.5 2 1 0 2 2 2 0 AAA ATPase domain AAA_30 PF13604.6 KKK22667.1 - 0.026 14.2 0.0 0.076 12.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 KKK22667.1 - 0.052 14.0 0.0 0.27 11.7 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 KKK22667.1 - 0.054 13.2 0.1 0.71 9.6 0.0 2.5 2 1 1 3 3 3 0 IstB-like ATP binding protein SbcCD_C PF13558.6 KKK22667.1 - 0.07 13.4 0.8 1.3 9.3 0.8 2.8 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit ABC_ATPase PF09818.9 KKK22667.1 - 0.084 11.7 0.3 0.34 9.7 0.1 1.8 2 0 0 2 2 2 0 Predicted ATPase of the ABC class DEAD PF00270.29 KKK22667.1 - 0.16 11.8 0.0 1.8 8.3 0.1 2.5 2 1 0 2 2 2 0 DEAD/DEAH box helicase Nucleoside_tran PF01733.18 KKK22668.1 - 1.3e-47 162.7 12.6 1.3e-47 162.7 12.6 2.5 2 1 0 2 2 2 1 Nucleoside transporter MFS_1 PF07690.16 KKK22668.1 - 0.00014 20.9 36.9 0.00016 20.8 22.4 2.3 1 1 1 2 2 2 1 Major Facilitator Superfamily p53-inducible11 PF14936.6 KKK22668.1 - 0.21 11.6 4.2 0.079 13.0 0.8 2.0 2 0 0 2 2 2 0 Tumour protein p53-inducible protein 11 Asp5 PF17000.5 KKK22668.1 - 9.4 6.4 9.5 0.14 12.3 1.0 2.5 2 1 0 2 2 2 0 Accessory secretory protein Sec, Asp5 Haspin_kinase PF12330.8 KKK22669.1 - 2.7e-40 138.5 0.0 4.2e-40 137.8 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain SNARE PF05739.19 KKK22670.1 - 1.9e-14 53.4 0.8 3.5e-14 52.5 0.8 1.5 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.25 KKK22670.1 - 0.0036 17.0 9.7 0.0036 17.0 9.7 1.9 2 1 0 2 2 2 1 Syntaxin Citrate_synt PF00285.21 KKK22670.1 - 0.067 12.2 0.1 0.11 11.5 0.1 1.3 1 0 0 1 1 1 0 Citrate synthase, C-terminal domain HlyD_D4 PF16572.5 KKK22670.1 - 0.068 13.0 0.1 0.32 10.9 0.0 2.1 2 0 0 2 2 2 0 Long alpha hairpin domain of cation efflux system protein, CusB GCP_C_terminal PF04130.13 KKK22670.1 - 0.083 12.3 2.1 0.1 12.0 1.4 1.5 1 1 0 1 1 1 0 Gamma tubulin complex component C-terminal DASH_Dad4 PF08650.10 KKK22670.1 - 0.26 11.3 0.9 3.3 7.7 0.1 2.4 2 0 0 2 2 2 0 DASH complex subunit Dad4 MCPsignal PF00015.21 KKK22670.1 - 0.4 10.5 7.0 0.1 12.4 0.4 2.6 3 0 0 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain SlyX PF04102.12 KKK22670.1 - 0.63 10.7 8.1 2.9 8.6 0.2 3.7 3 1 0 3 3 3 0 SlyX DUF948 PF06103.11 KKK22670.1 - 0.88 9.9 4.9 48 4.3 0.0 3.3 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) MukF_M PF17192.4 KKK22670.1 - 1.9 8.2 6.8 2.5 7.8 0.4 2.3 2 0 0 2 2 2 0 MukF middle domain Lebercilin PF15619.6 KKK22670.1 - 2 8.0 6.9 7.8 6.1 0.8 2.3 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease BBP1_C PF15272.6 KKK22670.1 - 2.8 7.7 6.6 10 5.9 0.6 2.7 1 1 1 3 3 3 0 Spindle pole body component BBP1, C-terminal CTD_bind PF04818.13 KKK22671.1 - 1.2e-17 64.5 0.1 2.9e-17 63.2 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase II-binding domain. DnaG_DnaB_bind PF08278.11 KKK22671.1 - 0.15 12.6 3.2 0.34 11.5 0.3 2.3 2 0 0 2 2 2 0 DNA primase DnaG DnaB-binding Clathrin_lg_ch PF01086.17 KKK22672.1 - 3.4e-68 230.1 1.8 3.8e-68 230.0 1.8 1.0 1 0 0 1 1 1 1 Clathrin light chain DUF3246 PF11596.8 KKK22693.1 - 1.1e-05 25.0 1.8 1.7e-05 24.4 1.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3246) SPX PF03105.19 KKK22693.1 - 0.078 12.9 2.6 0.09 12.7 2.6 1.1 1 0 0 1 1 1 0 SPX domain Spt20 PF12090.8 KKK22693.1 - 0.097 12.3 2.6 0.15 11.7 2.6 1.2 1 0 0 1 1 1 0 Spt20 family FAM176 PF14851.6 KKK22693.1 - 0.27 10.9 3.1 0.3 10.7 0.1 2.2 3 0 0 3 3 3 0 FAM176 family Pox_Ag35 PF03286.14 KKK22693.1 - 3.9 7.2 9.3 3.7 7.3 7.8 1.7 1 1 0 1 1 1 0 Pox virus Ag35 surface protein EF-hand_9 PF14658.6 KKK22694.1 - 3.7e-11 43.2 0.0 4e-05 23.8 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 KKK22694.1 - 7.9e-11 42.3 0.1 2.3e-06 27.9 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KKK22694.1 - 6.2e-09 35.1 0.1 0.013 15.3 0.0 3.3 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 KKK22694.1 - 3.4e-08 32.5 0.0 0.07 12.7 0.0 3.6 3 1 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 KKK22694.1 - 5.1e-07 29.4 0.1 3.8e-05 23.4 0.0 3.0 3 0 0 3 3 3 1 EF-hand domain pair DUF3216 PF11505.8 KKK22694.1 - 0.036 14.3 0.0 0.061 13.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3216) Xan_ur_permease PF00860.20 KKK22695.1 - 7.8e-64 215.8 31.1 3e-63 213.8 31.1 1.7 1 1 0 1 1 1 1 Permease family FA_desaturase PF00487.24 KKK22696.1 - 8.8e-19 68.3 14.3 8.8e-19 68.3 14.3 1.7 1 1 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 KKK22696.1 - 2.7e-17 62.7 0.7 6.7e-17 61.4 0.1 1.9 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Rad51 PF08423.11 KKK22697.1 - 1.9e-13 50.3 0.0 5.1e-12 45.6 0.0 2.2 1 1 0 1 1 1 1 Rad51 RecA PF00154.21 KKK22697.1 - 4.5e-06 26.3 0.0 0.00013 21.6 0.0 2.2 2 0 0 2 2 2 1 recA bacterial DNA recombination protein DnaB_C PF03796.15 KKK22697.1 - 4.8e-06 26.1 0.0 0.0004 19.8 0.0 2.2 2 0 0 2 2 2 1 DnaB-like helicase C terminal domain ATPase PF06745.13 KKK22697.1 - 5.2e-06 26.0 0.0 1.1e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 KaiC AAA_25 PF13481.6 KKK22697.1 - 3e-05 23.7 0.3 0.0031 17.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 KKK22697.1 - 6.6e-05 22.7 0.0 0.00013 21.8 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA PF00004.29 KKK22697.1 - 0.0002 21.8 0.1 0.00061 20.2 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) CbiA PF01656.23 KKK22697.1 - 0.00025 21.1 0.0 0.00034 20.7 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_22 PF13401.6 KKK22697.1 - 0.00079 19.7 0.0 0.0024 18.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 KKK22697.1 - 0.0018 18.2 0.0 0.0027 17.7 0.0 1.4 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_16 PF13191.6 KKK22697.1 - 0.0018 18.7 0.0 0.0033 17.8 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.6 KKK22697.1 - 0.0046 16.7 0.0 0.0084 15.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 KKK22697.1 - 0.0096 15.7 0.0 0.018 14.8 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 KKK22697.1 - 0.021 15.2 0.1 0.44 10.9 0.0 2.5 2 1 0 2 2 2 0 RNA helicase AAA_31 PF13614.6 KKK22697.1 - 0.032 14.1 0.0 0.069 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KKK22697.1 - 0.044 13.9 0.0 0.13 12.5 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KKK22697.1 - 0.046 14.3 0.1 0.19 12.3 0.0 2.1 3 0 0 3 3 2 0 AAA domain APS_kinase PF01583.20 KKK22697.1 - 0.049 13.5 0.0 2.2 8.1 0.0 2.3 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_11 PF13086.6 KKK22697.1 - 0.05 13.4 0.2 0.11 12.2 0.0 1.7 2 1 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KKK22697.1 - 0.092 13.3 0.0 0.23 12.0 0.0 1.6 1 1 0 1 1 1 0 ABC transporter PhoH PF02562.16 KKK22697.1 - 0.1 12.0 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein NB-ARC PF00931.22 KKK22697.1 - 0.11 11.6 0.0 0.2 10.8 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain CLP1_P PF16575.5 KKK22697.1 - 0.13 12.0 0.0 0.33 10.7 0.0 1.6 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_35 PF14516.6 KKK22697.1 - 0.16 10.8 0.0 0.28 10.0 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain MOSC PF03473.17 KKK22698.1 - 1.7e-22 79.8 0.0 5.2e-22 78.3 0.0 1.8 2 0 0 2 2 2 1 MOSC domain MOSC_N PF03476.16 KKK22698.1 - 1.6e-09 37.7 0.0 4.2e-09 36.3 0.0 1.7 1 1 0 1 1 1 1 MOSC N-terminal beta barrel domain LCE PF14672.6 KKK22698.1 - 6.5 7.4 11.0 0.46 11.1 1.3 2.7 2 0 0 2 2 2 0 Late cornified envelope 5-FTHF_cyc-lig PF01812.20 KKK22700.1 - 8.9e-18 64.8 0.0 1e-17 64.6 0.0 1.2 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family LSM PF01423.22 KKK22701.1 - 4.5e-13 48.7 0.0 5.2e-13 48.5 0.0 1.1 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 KKK22701.1 - 0.0014 18.3 0.1 0.002 17.7 0.1 1.3 1 0 0 1 1 1 1 Hfq protein YqeY PF09424.10 KKK22702.1 - 2.7e-19 69.6 1.5 3.3e-19 69.4 1.5 1.1 1 0 0 1 1 1 1 Yqey-like protein Cellulase PF00150.18 KKK22702.1 - 0.02 14.3 0.0 0.043 13.2 0.0 1.5 2 0 0 2 2 2 0 Cellulase (glycosyl hydrolase family 5) ParcG PF10274.9 KKK22702.1 - 0.035 14.2 0.0 0.044 13.9 0.0 1.2 1 0 0 1 1 1 0 Parkin co-regulated protein DUF659 PF04937.15 KKK22702.1 - 0.053 13.4 0.0 0.075 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF 659) Arm_vescicular PF18770.1 KKK22702.1 - 0.13 12.2 0.1 0.97 9.4 0.0 2.2 2 0 0 2 2 2 0 Armadillo tether-repeat of vescicular transport factor Rot1 PF10681.9 KKK22703.1 - 3.2e-91 304.5 0.0 3.6e-91 304.3 0.0 1.0 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal TauD PF02668.16 KKK22704.1 - 7.9e-48 163.6 0.0 9.8e-48 163.3 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family UPF0302 PF08864.10 KKK22704.1 - 0.011 15.8 0.0 0.021 14.9 0.0 1.5 1 0 0 1 1 1 0 UPF0302 domain Nucleoporin_N PF08801.11 KKK22705.1 - 4.8e-92 309.0 0.1 7.8e-92 308.3 0.1 1.3 1 0 0 1 1 1 1 Nup133 N terminal like Nucleoporin_C PF03177.14 KKK22705.1 - 8e-47 160.3 2.4 1e-45 156.7 0.5 2.1 2 0 0 2 2 2 2 Non-repetitive/WGA-negative nucleoporin C-terminal DUF3802 PF12290.8 KKK22705.1 - 0.049 14.1 0.6 8.3 7.0 0.1 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF3802) Xpo1 PF08389.12 KKK22706.1 - 1.9e-23 83.2 0.0 1.4e-22 80.3 0.0 2.6 2 0 0 2 2 2 1 Exportin 1-like protein IBN_N PF03810.19 KKK22706.1 - 0.0002 21.2 0.3 0.00065 19.6 0.1 2.1 2 0 0 2 2 2 1 Importin-beta N-terminal domain Urb2 PF10441.9 KKK22706.1 - 0.013 15.5 0.0 0.2 11.6 0.0 2.8 2 1 0 3 3 3 0 Urb2/Npa2 family HEAT_EZ PF13513.6 KKK22706.1 - 0.023 15.2 0.4 1.2 9.7 0.0 4.0 4 0 0 4 4 4 0 HEAT-like repeat Importin_rep_3 PF18806.1 KKK22706.1 - 0.053 13.6 0.0 0.28 11.2 0.0 2.2 2 0 0 2 2 2 0 Importin 13 repeat Adaptin_N PF01602.20 KKK22706.1 - 0.065 11.8 0.2 0.22 10.0 0.1 1.8 2 0 0 2 2 2 0 Adaptin N terminal region HEAT_2 PF13646.6 KKK22706.1 - 0.12 12.7 0.0 0.6 10.5 0.0 2.2 1 0 0 1 1 1 0 HEAT repeats Fungal_trans PF04082.18 KKK22707.1 - 2.1e-66 223.7 0.1 2.9e-66 223.2 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 KKK22707.1 - 1.1e-05 25.6 11.7 0.0011 19.3 1.4 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KKK22707.1 - 0.031 15.1 9.9 0.19 12.6 1.2 3.1 2 0 0 2 2 2 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KKK22707.1 - 0.2 12.2 10.3 0.079 13.4 2.0 2.8 2 0 0 2 2 2 0 Zinc-finger double domain Ogr_Delta PF04606.12 KKK22707.1 - 1.3 9.0 3.8 1.3 9.0 0.8 2.3 1 1 1 2 2 2 0 Ogr/Delta-like zinc finger Pkinase PF00069.25 KKK22741.1 - 1.8e-67 227.5 0.0 4.4e-67 226.2 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK22741.1 - 4.4e-32 111.4 0.0 7.1e-32 110.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 KKK22741.1 - 3.5e-10 40.1 0.4 1.3e-09 38.3 0.2 2.2 2 0 0 2 2 2 1 FHA domain Yop-YscD_cpl PF16697.5 KKK22741.1 - 0.0015 18.8 0.0 0.0038 17.5 0.0 1.6 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Kdo PF06293.14 KKK22741.1 - 0.0028 17.0 0.1 0.0049 16.2 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KKK22741.1 - 0.0088 16.0 0.1 5.5 6.8 0.1 3.0 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KKK22741.1 - 0.0088 15.4 0.0 0.022 14.1 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KKK22741.1 - 0.02 13.7 0.0 0.04 12.7 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase Glyco_transf_34 PF05637.12 KKK22742.1 - 8.8e-60 202.4 0.7 1.3e-59 201.9 0.7 1.1 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family NDUFB10 PF10249.9 KKK22743.1 - 0.14 12.7 0.0 0.14 12.7 0.0 1.0 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase subunit 10 Glutaredoxin PF00462.24 KKK22744.1 - 1e-18 67.2 0.0 8.2e-17 61.2 0.0 2.6 3 1 0 3 3 3 1 Glutaredoxin Thioredoxin PF00085.20 KKK22744.1 - 8.8e-14 51.4 0.0 2.4e-13 50.0 0.0 1.7 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_8 PF13905.6 KKK22744.1 - 0.00024 21.4 0.0 0.0014 18.9 0.0 2.1 1 1 1 2 2 2 1 Thioredoxin-like HyaE PF07449.11 KKK22744.1 - 0.081 12.9 0.0 0.39 10.7 0.0 2.1 3 0 0 3 3 3 0 Hydrogenase-1 expression protein HyaE Thioredoxin_2 PF13098.6 KKK22744.1 - 0.14 12.6 0.2 0.98 9.9 0.1 2.5 2 2 0 2 2 2 0 Thioredoxin-like domain TraF PF13728.6 KKK22744.1 - 0.16 11.8 0.1 4.2 7.1 0.1 2.1 2 0 0 2 2 2 0 F plasmid transfer operon protein RNase_T PF00929.24 KKK22745.1 - 2.7e-10 41.0 0.0 1.1e-09 39.0 0.0 1.9 1 1 0 1 1 1 1 Exonuclease Ribosomal_60s PF00428.19 KKK22745.1 - 6 7.5 7.8 1.3e+02 3.3 0.0 2.9 3 0 0 3 3 3 0 60s Acidic ribosomal protein Yippee-Mis18 PF03226.14 KKK22746.1 - 0.19 11.9 1.7 0.41 10.9 1.7 1.5 1 0 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DUF2703 PF10865.8 KKK22746.1 - 0.22 11.7 3.8 0.19 11.9 0.2 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF2703) Beta_elim_lyase PF01212.21 KKK22747.1 - 2.5e-69 233.8 0.0 2.9e-69 233.6 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase OKR_DC_1 PF01276.20 KKK22747.1 - 0.0017 17.1 0.0 0.0026 16.6 0.0 1.1 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain CAF1A PF12253.8 KKK22752.1 - 1.8e-21 76.1 6.9 1.8e-21 76.1 6.9 3.8 2 1 0 2 2 2 1 Chromatin assembly factor 1 subunit A CAF-1_p150 PF11600.8 KKK22752.1 - 1.4e-06 28.1 56.1 3.8e-06 26.7 56.1 1.7 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal TFIIF_alpha PF05793.12 KKK22752.1 - 0.0018 17.0 29.0 0.0018 17.0 29.0 2.2 2 0 0 2 2 2 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF262 PF03235.14 KKK22752.1 - 0.076 13.2 3.3 0.19 11.9 3.3 1.7 1 0 0 1 1 1 0 Protein of unknown function DUF262 SprA-related PF12118.8 KKK22752.1 - 0.88 8.6 21.7 1.5 7.9 21.7 1.3 1 0 0 1 1 1 0 SprA-related family SLC12 PF03522.15 KKK22752.1 - 1.2 8.0 18.7 2.2 7.2 18.7 1.3 1 0 0 1 1 1 0 Solute carrier family 12 DUF2151 PF10221.9 KKK22752.1 - 6 5.3 17.8 8.9 4.8 17.8 1.2 1 0 0 1 1 1 0 Cell cycle and development regulator IPP-2 PF04979.14 KKK22754.1 - 3.6e-18 66.6 22.6 5e-18 66.1 18.5 2.7 2 1 0 2 2 2 1 Protein phosphatase inhibitor 2 (IPP-2) GFO_IDH_MocA PF01408.22 KKK22757.1 - 5.7e-24 85.2 0.0 8.7e-24 84.6 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KKK22757.1 - 1.1e-14 54.4 0.0 1.8e-14 53.7 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.16 KKK22757.1 - 0.00011 22.8 0.0 0.00019 22.1 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain DapB_N PF01113.20 KKK22757.1 - 0.00087 19.4 0.0 0.0016 18.5 0.0 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus ADH_zinc_N_2 PF13602.6 KKK22757.1 - 0.013 16.5 0.1 0.087 13.9 0.0 2.3 3 1 1 4 4 4 0 Zinc-binding dehydrogenase Sacchrp_dh_NADP PF03435.18 KKK22757.1 - 0.015 15.6 0.0 0.025 14.8 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain HPP PF04982.13 KKK22758.1 - 3.8e-36 123.9 12.2 6.8e-36 123.1 12.2 1.4 1 0 0 1 1 1 1 HPP family Ycf66_N PF07444.11 KKK22758.1 - 0.16 12.2 3.0 1.6 9.0 0.2 2.6 2 0 0 2 2 2 0 Ycf66 protein N-terminus ArAE_1 PF06081.11 KKK22758.1 - 1.5 8.9 8.3 4.7 7.3 8.3 1.7 1 1 0 1 1 1 0 Aromatic acid exporter family member 1 Glyco_hydro_3 PF00933.21 KKK22759.1 - 1.6e-58 198.6 0.0 2.1e-58 198.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 KKK22759.1 - 4.1e-54 183.6 0.0 6.8e-54 182.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 KKK22759.1 - 1.1e-20 73.5 1.6 1.1e-20 73.5 1.6 2.0 2 0 0 2 2 2 1 Fibronectin type III-like domain DUF5441 PF17513.2 KKK22759.1 - 0.015 15.1 0.1 0.26 11.0 0.1 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5441) Sugar-bind PF04198.13 KKK22759.1 - 0.098 11.8 0.0 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 Putative sugar-binding domain Rootletin PF15035.6 KKK22760.1 - 0.048 13.7 4.8 0.17 11.9 4.8 1.8 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion YabA PF06156.13 KKK22760.1 - 1.4 9.6 4.5 29 5.4 0.5 2.5 2 0 0 2 2 2 0 Initiation control protein YabA WD40 PF00400.32 KKK22761.1 - 5.2e-14 52.4 15.2 0.00014 22.5 0.9 5.4 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKK22761.1 - 0.0008 19.7 0.1 0.29 11.5 0.0 3.0 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nop14 PF04147.12 KKK22761.1 - 0.45 8.7 10.2 0.61 8.2 10.2 1.1 1 0 0 1 1 1 0 Nop14-like family TFIIF_alpha PF05793.12 KKK22761.1 - 0.79 8.2 13.6 1.2 7.6 13.6 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Mg_trans_NIPA PF05653.14 KKK22762.1 - 1.2e-41 142.7 14.4 9.3e-37 126.7 10.7 3.2 2 1 0 2 2 2 2 Magnesium transporter NIPA Ctr PF04145.15 KKK22762.1 - 0.069 13.8 0.1 1.7 9.2 0.0 2.8 3 0 0 3 3 3 0 Ctr copper transporter family BTP PF05232.12 KKK22762.1 - 2.1 8.5 8.0 3.1 7.9 1.0 2.7 2 0 0 2 2 2 0 Chlorhexidine efflux transporter UQ_con PF00179.26 KKK22763.1 - 1.4e-43 148.0 0.0 1.7e-43 147.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.10 KKK22763.1 - 1.9e-07 30.8 1.2 3.8e-06 26.6 0.0 2.3 1 1 1 2 2 2 1 Fungal ubiquitin-associated domain Prok-E2_B PF14461.6 KKK22763.1 - 0.00059 19.6 0.0 0.00093 18.9 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 KKK22763.1 - 0.013 15.7 0.0 0.03 14.6 0.0 1.6 1 0 0 1 1 1 0 RWD domain DUF1421 PF07223.11 KKK22763.1 - 0.062 13.1 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 UBA-like domain (DUF1421) SnAPC_2_like PF11035.8 KKK22763.1 - 0.074 13.2 0.0 0.089 12.9 0.0 1.1 1 0 0 1 1 1 0 Small nuclear RNA activating complex subunit 2, SNAP190 Myb AAA PF00004.29 KKK22764.1 - 6.1e-41 139.9 0.0 1.2e-40 139.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KKK22764.1 - 1.8e-10 40.4 0.5 3.3e-10 39.6 0.5 1.4 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 KKK22764.1 - 1.3e-09 37.8 0.1 2.4e-09 37.0 0.1 1.5 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_22 PF13401.6 KKK22764.1 - 2.2e-06 28.0 0.2 0.02 15.1 0.1 2.5 1 1 1 2 2 2 2 AAA domain AAA_2 PF07724.14 KKK22764.1 - 1.1e-05 25.6 0.0 2.4e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 KKK22764.1 - 1.2e-05 24.6 0.0 2e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.14 KKK22764.1 - 4e-05 23.6 0.0 0.00011 22.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KKK22764.1 - 0.00027 21.4 0.3 0.0036 17.7 0.3 2.2 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 KKK22764.1 - 0.00066 19.5 0.0 0.0013 18.5 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 KKK22764.1 - 0.0028 17.9 0.3 0.0073 16.6 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_18 PF13238.6 KKK22764.1 - 0.0041 17.7 0.2 0.011 16.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KKK22764.1 - 0.014 15.5 0.0 0.031 14.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 KKK22764.1 - 0.016 14.7 0.6 0.51 9.7 0.1 2.2 2 0 0 2 2 2 0 PhoH-like protein IstB_IS21 PF01695.17 KKK22764.1 - 0.017 14.9 0.0 0.038 13.7 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_14 PF13173.6 KKK22764.1 - 0.02 14.9 0.0 0.04 14.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 KKK22764.1 - 0.02 14.7 0.0 0.04 13.8 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.13 KKK22764.1 - 0.029 13.6 0.7 0.064 12.5 0.1 1.8 2 1 0 2 2 2 0 TIP49 P-loop domain ATPase PF06745.13 KKK22764.1 - 0.034 13.5 0.2 0.56 9.5 0.1 2.2 1 1 0 2 2 2 0 KaiC NACHT PF05729.12 KKK22764.1 - 0.037 14.0 0.2 0.65 9.9 0.1 2.3 1 1 0 2 2 2 0 NACHT domain RNA_helicase PF00910.22 KKK22764.1 - 0.046 14.1 0.0 0.1 13.0 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Mg_chelatase PF01078.21 KKK22764.1 - 0.06 12.7 0.1 0.12 11.7 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.12 KKK22764.1 - 0.067 12.5 0.0 0.18 11.0 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin AAA_25 PF13481.6 KKK22764.1 - 0.074 12.6 1.5 0.58 9.7 0.4 2.4 1 1 0 2 2 2 0 AAA domain Prot_ATP_OB_N PF17758.1 KKK22764.1 - 0.14 11.8 0.5 1 9.0 0.0 2.5 2 0 0 2 2 2 0 Proteasomal ATPase OB N-terminal domain AAA_24 PF13479.6 KKK22764.1 - 0.17 11.6 2.0 0.3 10.8 0.3 2.2 2 1 0 2 2 2 0 AAA domain DUF2075 PF09848.9 KKK22764.1 - 0.18 11.0 0.0 0.27 10.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ABC_tran PF00005.27 KKK22765.1 - 1.6e-47 161.5 0.1 3.1e-22 79.6 0.0 2.7 3 0 0 3 3 2 2 ABC transporter ABC_tran_Xtn PF12848.7 KKK22765.1 - 2.5e-21 75.5 2.0 2.5e-21 75.5 2.0 2.9 3 0 0 3 3 2 1 ABC transporter AAA_21 PF13304.6 KKK22765.1 - 5.1e-17 62.6 0.5 0.0012 18.7 0.0 4.2 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KKK22765.1 - 4.9e-11 42.5 0.4 0.0096 15.4 0.1 4.4 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KKK22765.1 - 9e-08 31.8 0.3 0.002 17.8 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 KKK22765.1 - 6.4e-07 30.1 5.1 0.053 14.0 0.0 3.6 3 1 0 3 3 3 2 AAA domain AAA_15 PF13175.6 KKK22765.1 - 2.3e-06 27.6 0.0 0.038 13.7 0.0 2.9 3 0 0 3 3 3 2 AAA ATPase domain RsgA_GTPase PF03193.16 KKK22765.1 - 3.8e-06 26.9 0.9 0.0054 16.6 0.0 2.8 3 0 0 3 3 3 2 RsgA GTPase MMR_HSR1 PF01926.23 KKK22765.1 - 1.4e-05 25.1 0.0 0.027 14.6 0.0 3.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KKK22765.1 - 1.9e-05 25.1 0.0 0.13 12.7 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 KKK22765.1 - 3.2e-05 24.2 0.0 0.17 12.1 0.0 2.7 2 1 0 2 2 2 2 AAA domain NB-ARC PF00931.22 KKK22765.1 - 3.7e-05 23.0 0.0 0.41 9.8 0.0 3.2 2 1 0 2 2 2 2 NB-ARC domain NACHT PF05729.12 KKK22765.1 - 0.00012 22.0 0.2 0.17 11.8 0.0 2.6 2 0 0 2 2 2 2 NACHT domain AAA_18 PF13238.6 KKK22765.1 - 0.00013 22.6 0.1 0.067 13.7 0.0 3.0 3 0 0 3 3 2 1 AAA domain RNA_helicase PF00910.22 KKK22765.1 - 0.0002 21.7 0.5 1.9 8.9 0.0 3.3 3 0 0 3 3 3 2 RNA helicase AAA PF00004.29 KKK22765.1 - 0.00026 21.4 0.1 1.1 9.7 0.0 3.2 3 1 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 KKK22765.1 - 0.00026 21.3 0.0 0.094 13.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_27 PF13514.6 KKK22765.1 - 0.00035 20.2 0.5 0.2 11.2 0.0 2.7 3 0 0 3 3 2 1 AAA domain AAA_33 PF13671.6 KKK22765.1 - 0.00047 20.3 1.8 0.2 11.8 0.1 3.1 4 0 0 4 4 2 1 AAA domain Roc PF08477.13 KKK22765.1 - 0.0012 19.0 0.0 2.2 8.5 0.0 3.0 2 1 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_5 PF07728.14 KKK22765.1 - 0.0013 18.7 0.2 1.8 8.5 0.1 2.6 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 KKK22765.1 - 0.0014 18.4 0.7 1.9 8.2 0.1 3.4 4 0 0 4 4 3 1 AAA domain AAA_14 PF13173.6 KKK22765.1 - 0.0016 18.4 0.0 1.9 8.5 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 KKK22765.1 - 0.0062 16.1 0.1 2 7.9 0.0 2.8 3 0 0 3 3 3 1 P-loop containing dynein motor region GST_C_3 PF14497.6 KKK22765.1 - 0.014 15.6 0.2 0.036 14.2 0.2 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DUF87 PF01935.17 KKK22765.1 - 0.026 14.6 0.5 8.6 6.4 0.0 3.1 3 0 0 3 3 3 0 Helicase HerA, central domain ATPase_2 PF01637.18 KKK22765.1 - 0.026 14.4 0.1 3.2 7.6 0.0 2.6 3 0 0 3 3 2 0 ATPase domain predominantly from Archaea Phage_tail_2 PF06199.11 KKK22765.1 - 0.03 14.4 0.0 0.077 13.1 0.0 1.7 1 1 0 1 1 1 0 Phage tail tube protein AAA_25 PF13481.6 KKK22765.1 - 0.035 13.7 0.0 1.2 8.7 0.0 2.8 3 0 0 3 3 3 0 AAA domain Dynamin_N PF00350.23 KKK22765.1 - 0.035 14.1 4.4 7.6 6.6 0.0 4.0 4 1 0 4 4 4 0 Dynamin family NTPase_1 PF03266.15 KKK22765.1 - 0.04 13.8 0.1 3.9 7.4 0.1 2.6 2 0 0 2 2 2 0 NTPase DUF2813 PF11398.8 KKK22765.1 - 0.048 12.9 1.3 5.9 6.0 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2813) Ras PF00071.22 KKK22765.1 - 0.052 13.1 0.0 4.7 6.8 0.0 2.6 2 0 0 2 2 2 0 Ras family FeoB_N PF02421.18 KKK22765.1 - 0.077 12.5 0.1 4.8 6.7 0.0 2.9 3 0 0 3 3 3 0 Ferrous iron transport protein B MCM PF00493.23 KKK22765.1 - 0.09 11.9 0.1 2.9 6.9 0.0 2.2 2 0 0 2 2 2 0 MCM P-loop domain DAP3 PF10236.9 KKK22765.1 - 0.11 11.7 0.4 9.2 5.3 0.0 2.8 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 Cyclin_C_2 PF16899.5 KKK22766.1 - 5.6e-39 132.7 0.1 7.4e-36 122.7 0.0 2.4 2 0 0 2 2 2 2 Cyclin C-terminal domain Cyclin_N PF00134.23 KKK22766.1 - 8.3e-07 28.8 0.0 2.1e-06 27.5 0.0 1.7 1 0 0 1 1 1 1 Cyclin, N-terminal domain Ribosomal_60s PF00428.19 KKK22766.1 - 1.2 9.8 4.1 5.4 7.7 0.5 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein Sugar_tr PF00083.24 KKK22767.1 - 3.7e-79 266.7 24.6 4.5e-79 266.4 24.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKK22767.1 - 2.5e-18 66.1 49.0 1e-16 60.8 26.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily AAA_12 PF13087.6 KKK22768.1 - 6.1e-36 123.9 0.0 1.3e-35 122.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KKK22768.1 - 5.3e-28 98.5 0.4 5.3e-28 98.5 0.4 2.2 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KKK22768.1 - 1.7e-10 41.4 0.1 1.6e-09 38.3 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KKK22768.1 - 5.4e-07 29.5 0.0 0.0011 18.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain DUF2075 PF09848.9 KKK22768.1 - 0.0012 18.1 0.1 0.028 13.7 0.0 2.4 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) LXG PF04740.12 KKK22768.1 - 0.018 14.8 0.3 0.018 14.8 0.3 2.0 2 0 0 2 2 2 0 LXG domain of WXG superfamily ResIII PF04851.15 KKK22768.1 - 0.04 13.9 0.0 0.097 12.7 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit GvpK PF05121.12 KKK22768.1 - 0.99 9.5 4.0 0.95 9.5 1.5 2.3 2 0 0 2 2 2 0 Gas vesicle protein K Zn_clus PF00172.18 KKK22769.1 - 1.8e-06 28.0 10.8 1.8e-06 28.0 10.8 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KKK22769.1 - 0.0077 15.1 0.0 0.013 14.4 0.0 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Phage_holin_7_1 PF16081.5 KKK22769.1 - 0.05 13.8 0.1 0.099 12.8 0.1 1.4 1 0 0 1 1 1 0 Mycobacterial 2 TMS Phage Holin (M2 Hol) Family Methyltransf_24 PF13578.6 KKK22770.1 - 1.4e-12 48.6 0.0 2e-12 48.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.17 KKK22770.1 - 6.3e-12 45.1 0.0 8.4e-12 44.7 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Ldh_1_N PF00056.23 KKK22771.1 - 1.1e-24 87.1 0.4 3.7e-22 78.9 0.4 2.2 1 1 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 KKK22771.1 - 2.7e-15 56.7 0.0 4e-15 56.1 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain F420_oxidored PF03807.17 KKK22771.1 - 0.0064 17.0 0.2 0.023 15.3 0.2 2.0 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Glyco_hydro_4 PF02056.16 KKK22771.1 - 0.017 14.6 0.1 0.033 13.8 0.1 1.6 1 1 0 1 1 1 0 Family 4 glycosyl hydrolase ApbA PF02558.16 KKK22771.1 - 0.08 12.6 0.2 0.39 10.4 0.3 2.0 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Bot1p PF12298.8 KKK22783.1 - 1.1e-57 195.0 3.5 1.1e-57 195.0 3.5 2.0 2 0 0 2 2 2 1 Eukaryotic mitochondrial regulator protein Amidase PF01425.21 KKK22789.1 - 1.4e-99 334.1 0.0 1.9e-99 333.7 0.0 1.2 1 0 0 1 1 1 1 Amidase EAP30 PF04157.16 KKK22789.1 - 1.1e-41 142.6 0.1 1.7e-41 142.1 0.1 1.3 1 0 0 1 1 1 1 EAP30/Vps36 family Vps36-NZF-N PF16988.5 KKK22789.1 - 6.9e-24 83.0 2.3 6.9e-24 83.0 2.3 2.5 2 1 0 2 2 2 1 Vacuolar protein sorting 36 NZF-N zinc-finger domain Vps36_ESCRT-II PF11605.8 KKK22789.1 - 8.6e-13 48.3 0.0 1.8e-12 47.3 0.0 1.5 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 zf-Sec23_Sec24 PF04810.15 KKK22789.1 - 0.0011 19.0 5.1 0.0069 16.4 0.7 2.7 2 0 0 2 2 2 1 Sec23/Sec24 zinc finger zf-RanBP PF00641.18 KKK22789.1 - 0.0043 16.3 6.0 0.4 10.0 0.3 2.6 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others DZR PF12773.7 KKK22789.1 - 1.2 9.2 3.3 1.3 9.1 0.3 2.2 2 0 0 2 2 2 0 Double zinc ribbon Phosducin PF02114.16 KKK22794.1 - 1.8e-12 46.8 0.0 7.5e-10 38.2 0.0 2.1 2 0 0 2 2 2 2 Phosducin zf-MYND PF01753.18 KKK22795.1 - 6.5e-08 32.5 20.3 1.5e-07 31.3 20.3 1.7 1 0 0 1 1 1 1 MYND finger WD40 PF00400.32 KKK22796.1 - 1.6e-39 133.1 21.4 3.9e-06 27.5 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKK22796.1 - 5.4e-16 58.7 0.0 0.00044 20.5 0.1 5.2 1 1 5 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KKK22796.1 - 2.8e-05 24.1 0.0 0.11 12.3 0.0 2.8 1 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 KKK22796.1 - 0.0008 18.8 0.0 0.022 14.1 0.0 2.8 2 1 1 3 3 3 1 WD40-like domain Ge1_WD40 PF16529.5 KKK22796.1 - 0.046 12.7 0.2 21 3.9 0.0 3.6 3 1 1 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DSPc PF00782.20 KKK22818.1 - 4.6e-30 104.1 0.0 2.4e-22 79.2 0.0 2.2 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KKK22818.1 - 9e-05 22.2 0.0 0.0026 17.4 0.0 2.2 2 0 0 2 2 2 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 KKK22818.1 - 0.02 15.0 0.0 0.1 12.7 0.1 2.0 2 0 0 2 2 2 0 Inositol hexakisphosphate Peptidase_M60 PF13402.6 KKK22819.1 - 0.12 11.9 0.5 0.18 11.3 0.5 1.2 1 0 0 1 1 1 0 Peptidase M60, enhancin and enhancin-like Catalase-rel PF06628.12 KKK22819.1 - 0.15 12.3 0.0 0.43 10.8 0.0 1.7 2 0 0 2 2 2 0 Catalase-related immune-responsive ANAPC4_WD40 PF12894.7 KKK22820.1 - 0.00018 21.8 0.0 0.06 13.7 0.0 3.5 4 1 1 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KKK22820.1 - 0.00074 20.3 0.1 0.28 12.1 0.0 4.0 5 0 0 5 5 5 1 WD domain, G-beta repeat CNH PF00780.22 KKK22820.1 - 0.0008 19.1 0.1 0.21 11.2 0.1 2.4 2 0 0 2 2 2 2 CNH domain Coatomer_WDAD PF04053.14 KKK22820.1 - 0.0067 15.5 0.0 0.039 13.0 0.0 2.1 2 0 0 2 2 2 1 Coatomer WD associated region MMS1_N PF10433.9 KKK22820.1 - 0.066 11.8 0.2 2.4 6.7 0.0 2.7 3 0 0 3 3 3 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term Ge1_WD40 PF16529.5 KKK22820.1 - 0.18 10.8 0.0 0.63 8.9 0.0 1.9 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein RPN1_RPN2_N PF17781.1 KKK22821.1 - 2.5e-117 391.7 1.9 4e-117 391.0 1.9 1.3 1 0 0 1 1 1 1 RPN1/RPN2 N-terminal domain RIO1 PF01163.22 KKK22821.1 - 3.8e-40 137.5 0.7 3.4e-28 98.5 0.0 2.5 2 0 0 2 2 2 2 RIO1 family Rio2_N PF09202.11 KKK22821.1 - 2.3e-32 111.1 0.0 8.6e-32 109.2 0.0 2.1 1 0 0 1 1 1 1 Rio2, N-terminal RPN1_C PF18051.1 KKK22821.1 - 1.2e-26 92.4 0.0 2.9e-26 91.2 0.0 1.6 1 0 0 1 1 1 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal PC_rep PF01851.22 KKK22821.1 - 1.1e-15 57.1 15.7 7.7e-05 22.9 0.1 7.9 8 0 0 8 8 8 3 Proteasome/cyclosome repeat Kdo PF06293.14 KKK22821.1 - 2.3e-06 27.1 0.0 7.8e-05 22.1 0.0 2.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KKK22821.1 - 1.6e-05 25.0 0.0 0.063 13.2 0.0 2.7 1 1 1 2 2 2 2 Phosphotransferase enzyme family HEAT_2 PF13646.6 KKK22821.1 - 0.0034 17.8 0.5 5.4 7.5 0.0 3.9 3 1 0 3 3 3 1 HEAT repeats Cupin_8 PF13621.6 KKK22822.1 - 9.4e-38 130.4 0.0 2e-37 129.3 0.0 1.5 1 0 0 1 1 1 1 Cupin-like domain LCM PF04072.14 KKK22822.1 - 2.9e-17 63.2 0.0 5e-17 62.5 0.0 1.3 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Kelch_4 PF13418.6 KKK22822.1 - 2.3e-15 56.3 14.1 4.1e-05 23.5 0.0 5.9 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_5 PF13854.6 KKK22822.1 - 5.3e-09 35.9 0.0 7.5e-05 22.6 0.0 3.7 3 0 0 3 3 3 2 Kelch motif Cupin_4 PF08007.12 KKK22822.1 - 0.0002 21.0 0.0 0.00045 19.8 0.0 1.5 1 0 0 1 1 1 1 Cupin superfamily protein Kelch_3 PF13415.6 KKK22822.1 - 0.2 12.0 9.0 2 8.8 0.2 3.6 3 0 0 3 3 3 0 Galactose oxidase, central domain Kelch_6 PF13964.6 KKK22822.1 - 0.41 11.0 3.9 2.3 8.6 0.1 3.8 5 0 0 5 5 5 0 Kelch motif Mlh1_C PF16413.5 KKK22824.1 - 9.5e-102 340.0 0.0 6.8e-101 337.2 0.0 2.0 2 0 0 2 2 2 1 DNA mismatch repair protein Mlh1 C-terminus DNA_mis_repair PF01119.19 KKK22824.1 - 1e-31 109.1 0.2 1.8e-31 108.3 0.2 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 KKK22824.1 - 5.8e-13 48.9 0.0 2e-12 47.1 0.0 1.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 KKK22824.1 - 3.2e-08 34.1 0.0 3.9e-07 30.6 0.0 2.6 3 0 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TPR_14 PF13428.6 KKK22825.1 - 0.67 10.9 2.7 27 5.9 0.1 3.4 1 1 1 2 2 2 0 Tetratricopeptide repeat EF-hand_6 PF13405.6 KKK22826.1 - 1e-09 37.5 0.2 0.0018 18.1 0.0 3.1 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 KKK22826.1 - 3.2e-05 24.3 2.4 0.0064 16.9 0.8 2.8 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 KKK22826.1 - 0.00057 19.2 0.1 0.0032 16.9 0.0 2.2 2 0 0 2 2 2 1 EF hand Aldo_ket_red PF00248.21 KKK22853.1 - 7.4e-44 150.1 0.0 4.9e-42 144.1 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family UPF0061 PF02696.14 KKK22854.1 - 1.9e-125 419.3 0.0 2.4e-125 419.0 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family TOBE PF03459.17 KKK22854.1 - 0.12 12.7 0.0 0.29 11.4 0.0 1.5 1 0 0 1 1 1 0 TOBE domain RNase_HII PF01351.18 KKK22856.1 - 6.2e-48 163.3 0.0 7.9e-48 162.9 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease HII F-box PF00646.33 KKK22857.1 - 1.2e-08 34.6 1.4 2.5e-08 33.6 1.4 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KKK22857.1 - 2.2e-08 33.8 0.4 4.7e-08 32.8 0.4 1.5 1 0 0 1 1 1 1 F-box-like WD40 PF00400.32 KKK22857.1 - 0.024 15.5 1.2 9 7.4 0.5 3.9 3 0 0 3 3 3 0 WD domain, G-beta repeat zf-CCHC PF00098.23 KKK22858.1 - 3.7e-52 172.2 62.5 2.2e-09 37.0 2.0 7.3 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.6 KKK22858.1 - 2.3e-15 56.0 44.3 0.0053 16.5 0.7 7.1 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_3 PF13917.6 KKK22858.1 - 7.1e-06 25.9 46.8 0.013 15.5 0.5 6.6 3 2 4 7 7 7 6 Zinc knuckle zf-CCHC_5 PF14787.6 KKK22858.1 - 0.00056 19.6 44.7 0.24 11.2 1.2 7.1 6 1 1 7 7 7 7 GAG-polyprotein viral zinc-finger zf-CCHC_6 PF15288.6 KKK22858.1 - 0.0021 17.9 59.6 0.031 14.1 0.7 7.7 6 2 2 8 8 8 5 Zinc knuckle Pex16 PF08610.10 KKK22859.1 - 9.8e-140 465.3 0.0 1.1e-139 465.1 0.0 1.0 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) SAE2 PF08573.10 KKK22860.1 - 1.9e-34 119.1 0.0 1.9e-34 119.1 0.0 3.4 3 1 0 3 3 3 1 DNA repair protein endonuclease SAE2/CtIP C-terminus SH3BP5 PF05276.14 KKK22860.1 - 0.0021 17.9 7.4 0.0044 16.8 7.4 1.6 1 1 0 1 1 1 1 SH3 domain-binding protein 5 (SH3BP5) DUF4200 PF13863.6 KKK22860.1 - 0.0099 16.3 6.7 0.0099 16.3 6.7 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF4200) DUF1664 PF07889.12 KKK22860.1 - 1.7 8.7 3.7 1.6 8.8 1.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Bcr-Abl_Oligo PF09036.10 KKK22860.1 - 2 8.5 5.9 9 6.4 0.1 3.0 3 0 0 3 3 3 0 Bcr-Abl oncoprotein oligomerisation domain GldM_N PF12081.8 KKK22860.1 - 2.3 8.3 5.6 4.2 7.4 2.4 2.2 2 0 0 2 2 2 0 GldM N-terminal domain FUSC PF04632.12 KKK22860.1 - 2.3 6.6 3.7 4.4 5.7 3.7 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family AAA_13 PF13166.6 KKK22860.1 - 3.2 6.3 9.8 1.6 7.2 5.9 2.0 1 1 1 2 2 2 0 AAA domain KLRAQ PF10205.9 KKK22860.1 - 4.2 7.7 8.3 15 5.9 0.7 2.8 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein XhlA PF10779.9 KKK22860.1 - 5.1 7.4 5.2 1.6 9.0 1.1 2.3 2 0 0 2 2 2 0 Haemolysin XhlA A_deaminase PF00962.22 KKK22878.1 - 2.7e-122 408.2 0.0 3.7e-122 407.8 0.0 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase ELMO_CED12 PF04727.13 KKK22881.1 - 2.5e-51 174.3 0.1 3.8e-51 173.7 0.1 1.3 1 0 0 1 1 1 1 ELMO/CED-12 family PH_12 PF16457.5 KKK22881.1 - 6.1e-34 117.4 0.0 3.6e-33 114.9 0.0 2.4 3 1 0 3 3 3 1 Pleckstrin homology domain DUF3361 PF11841.8 KKK22881.1 - 2.1e-16 60.3 0.1 6.2e-16 58.7 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3361) Sec10 PF07393.11 KKK22883.1 - 3e-241 802.8 0.0 3.5e-241 802.6 0.0 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 MarR_2 PF12802.7 KKK22883.1 - 0.0025 17.7 0.2 0.42 10.5 0.0 2.9 2 0 0 2 2 2 1 MarR family Motilin_assoc PF04643.12 KKK22883.1 - 0.15 11.9 1.5 1.6 8.6 0.1 2.5 2 0 0 2 2 2 0 Motilin/ghrelin-associated peptide Tropomyosin PF00261.20 KKK22883.1 - 0.17 11.2 2.5 0.54 9.6 0.2 2.5 2 0 0 2 2 2 0 Tropomyosin GBP_C PF02841.14 KKK22883.1 - 0.75 9.1 4.1 0.81 9.0 0.0 2.7 3 0 0 3 3 3 0 Guanylate-binding protein, C-terminal domain Dynamin_M PF01031.20 KKK22884.1 - 4.8e-111 370.5 0.0 9.3e-111 369.6 0.0 1.5 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.23 KKK22884.1 - 2.3e-55 187.2 0.0 5.5e-55 186.0 0.0 1.7 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 KKK22884.1 - 1.9e-31 108.0 1.1 5.2e-31 106.7 1.1 1.8 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 KKK22884.1 - 0.00017 21.7 0.2 0.0035 17.4 0.2 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase MAGE_N PF12440.8 KKK22884.1 - 0.0021 18.7 1.7 0.0021 18.7 1.7 2.0 2 0 0 2 2 2 1 Melanoma associated antigen family N terminal FeoB_N PF02421.18 KKK22884.1 - 0.068 12.7 0.1 5.1 6.6 0.0 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B SH3_9 PF14604.6 KKK22885.1 - 1.1e-26 92.4 5.1 5.7e-14 51.7 0.4 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 KKK22885.1 - 2.7e-26 90.9 4.5 1.4e-14 53.5 0.5 2.5 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.17 KKK22885.1 - 9.3e-17 60.5 0.1 1e-06 28.3 0.0 3.1 3 0 0 3 3 3 2 Variant SH3 domain Cofilin_ADF PF00241.20 KKK22885.1 - 3.6e-15 55.8 0.0 8.1e-15 54.7 0.0 1.6 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Trypan_PARP PF05887.11 KKK22885.1 - 0.0019 18.2 3.3 0.0019 18.2 3.3 4.1 3 1 0 4 4 4 1 Procyclic acidic repetitive protein (PARP) Rad17 PF03215.15 KKK22886.1 - 1.7e-28 99.8 0.0 3.3e-28 98.9 0.0 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 KKK22886.1 - 0.0012 19.2 0.0 0.0031 17.9 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 KKK22886.1 - 0.017 15.5 0.0 0.041 14.3 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 KKK22886.1 - 0.04 13.0 0.0 0.071 12.2 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein ABC_tran PF00005.27 KKK22886.1 - 0.045 14.3 0.0 0.13 12.8 0.0 1.8 1 0 0 1 1 1 0 ABC transporter AAA_22 PF13401.6 KKK22886.1 - 0.057 13.7 0.0 0.15 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KKK22886.1 - 0.057 13.1 0.0 0.15 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KKK22886.1 - 0.057 13.8 0.0 0.45 10.9 0.0 2.3 2 0 0 2 2 2 0 RNA helicase RsgA_GTPase PF03193.16 KKK22886.1 - 0.11 12.4 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_5 PF07728.14 KKK22886.1 - 0.17 11.9 0.0 0.43 10.6 0.0 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) UAA PF08449.11 KKK22887.1 - 5.8e-84 281.9 17.4 3.5e-83 279.3 17.4 1.8 1 1 0 1 1 1 1 UAA transporter family Nuc_sug_transp PF04142.15 KKK22887.1 - 0.00013 21.3 0.7 0.00013 21.3 0.7 2.2 2 0 0 2 2 2 1 Nucleotide-sugar transporter LAGLIDADG_3 PF14528.6 KKK22887.1 - 0.17 12.2 0.0 0.48 10.8 0.0 1.7 1 0 0 1 1 1 0 LAGLIDADG-like domain TPT PF03151.16 KKK22887.1 - 2.1 7.6 17.6 1.3 8.3 2.6 3.4 2 1 0 2 2 2 0 Triose-phosphate Transporter family Sortilin-Vps10 PF15902.5 KKK22888.1 - 1.6e-289 960.0 1.7 4.8e-149 496.9 0.0 2.1 2 0 0 2 2 2 2 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 KKK22888.1 - 1.2e-84 282.8 24.0 1.9e-44 152.0 1.6 2.7 3 0 0 3 3 3 2 Sortilin, neurotensin receptor 3, C-terminal BNR PF02012.20 KKK22888.1 - 2.2e-08 32.9 39.2 0.94 9.7 0.0 12.3 13 0 0 13 13 13 4 BNR/Asp-box repeat BNR_2 PF13088.6 KKK22888.1 - 6.5e-07 28.9 4.2 5.1 6.3 0.0 6.8 5 2 0 7 7 7 3 BNR repeat-like domain PSII_BNR PF14870.6 KKK22888.1 - 1.3e-06 27.9 4.2 0.014 14.7 0.0 6.1 5 2 1 6 6 6 1 Photosynthesis system II assembly factor YCF48 BNR_6 PF15899.5 KKK22888.1 - 0.00013 21.7 4.0 2.1 8.6 0.0 5.6 5 0 0 5 5 5 1 BNR-Asp box repeat CHB_HEX_C PF03174.13 KKK22888.1 - 0.0086 16.0 0.5 5.9 6.9 0.1 4.0 4 0 0 4 4 4 1 Chitobiase/beta-hexosaminidase C-terminal domain Mo-co_dimer PF03404.16 KKK22888.1 - 0.38 10.8 4.4 8.3 6.4 0.0 5.1 8 0 0 8 8 8 0 Mo-co oxidoreductase dimerisation domain preSET_CXC PF18264.1 KKK22888.1 - 2.4 8.7 7.9 3.7 8.1 0.5 2.9 2 0 0 2 2 2 0 CXC domain Pkinase PF00069.25 KKK22921.1 - 8.8e-57 192.5 0.0 1.2e-56 192.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK22921.1 - 2.3e-41 141.8 0.0 3.7e-41 141.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KKK22921.1 - 0.00011 21.1 0.6 0.00023 20.1 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 KKK22921.1 - 0.00012 21.6 0.0 0.00017 21.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KKK22921.1 - 0.00096 19.1 0.2 0.0047 16.9 0.0 2.1 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 KKK22921.1 - 0.0085 15.5 0.3 0.026 13.9 0.1 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 KKK22921.1 - 0.029 14.0 0.0 0.064 12.9 0.0 1.5 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 KKK22921.1 - 0.15 11.0 0.1 0.38 9.6 0.0 1.6 2 0 0 2 2 2 0 Haspin like kinase domain RIO1 PF01163.22 KKK22921.1 - 0.19 11.3 0.2 1 9.0 0.2 2.1 1 1 0 1 1 1 0 RIO1 family Glyco_hydro_43 PF04616.14 KKK22923.1 - 4.6e-35 121.3 0.1 7.1e-35 120.7 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 DUF5313 PF17240.2 KKK22923.1 - 0.056 13.9 0.2 0.11 13.0 0.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5313) Tim17 PF02466.19 KKK22924.1 - 7.6e-25 87.4 5.6 1e-24 87.1 5.6 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Pkinase PF00069.25 KKK22925.1 - 1.3e-44 152.6 0.0 4.6e-42 144.2 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KKK22925.1 - 2.4e-25 89.3 0.0 4e-25 88.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PX PF00787.24 KKK22926.1 - 3.1e-19 69.0 0.0 7.6e-18 64.5 0.0 2.8 3 0 0 3 3 3 1 PX domain Vps5 PF09325.10 KKK22926.1 - 3.1e-08 33.5 8.1 0.00028 20.5 1.1 2.1 2 0 0 2 2 2 2 Vps5 C terminal like Peptidase_C10 PF01640.17 KKK22926.1 - 0.0044 17.4 0.1 0.01 16.1 0.1 1.6 1 0 0 1 1 1 1 Peptidase C10 family DUF2428 PF10350.9 KKK22927.1 - 1.6e-64 217.9 0.0 2.9e-64 217.0 0.0 1.5 1 0 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) HEAT PF02985.22 KKK22927.1 - 0.013 15.7 6.1 24 5.5 0.1 5.7 6 0 0 6 6 6 0 HEAT repeat ADH_zinc_N PF00107.26 KKK22940.1 - 6.1e-17 61.8 0.3 1.3e-16 60.8 0.3 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KKK22940.1 - 3.7e-06 28.0 0.1 8.2e-06 26.9 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KKK22940.1 - 1.5e-05 24.8 0.0 3.1e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.25 KKK22940.1 - 0.052 13.0 0.1 0.098 12.1 0.1 1.5 1 0 0 1 1 1 0 short chain dehydrogenase FERM_C PF09380.10 KKK22940.1 - 0.09 13.2 0.0 0.17 12.3 0.0 1.4 1 0 0 1 1 1 0 FERM C-terminal PH-like domain PI3K_P85_iSH2 PF16454.5 KKK22940.1 - 0.13 11.8 0.1 0.3 10.7 0.1 1.5 1 0 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain TPP_enzyme_N PF02776.18 KKK22942.1 - 1.7e-20 73.4 0.0 4e-20 72.1 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 KKK22942.1 - 1.9e-14 53.6 0.0 4.6e-14 52.3 0.0 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 KKK22942.1 - 1e-13 51.3 0.0 2.5e-13 50.1 0.0 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Glycos_transf_1 PF00534.20 KKK22942.1 - 7.8e-13 48.3 0.0 1.5e-12 47.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KKK22942.1 - 3.9e-12 46.7 0.0 1.1e-11 45.3 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 DUF3492 PF11997.8 KKK22942.1 - 0.0072 16.1 0.0 0.015 15.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3492) Spherulin4 PF12138.8 KKK22943.1 - 3.5e-69 233.1 2.3 4.1e-69 232.9 2.3 1.0 1 0 0 1 1 1 1 Spherulation-specific family 4 Synaptobrevin PF00957.21 KKK22943.1 - 0.028 14.2 0.3 1.2 9.0 0.6 2.2 2 0 0 2 2 2 0 Synaptobrevin AI-2E_transport PF01594.16 KKK22943.1 - 1.3 8.1 5.1 0.83 8.7 2.9 1.6 2 0 0 2 2 2 0 AI-2E family transporter Spherulin4 PF12138.8 KKK22944.1 - 4.2e-61 206.6 0.0 4.7e-61 206.5 0.0 1.0 1 0 0 1 1 1 1 Spherulation-specific family 4 Spore_III_AB PF09548.10 KKK22944.1 - 0.23 11.6 0.0 0.35 11.0 0.0 1.2 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) Epimerase PF01370.21 KKK22945.1 - 1.3e-36 126.2 0.0 3.8e-35 121.5 0.0 2.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KKK22945.1 - 1.3e-34 120.1 0.0 3.9e-33 115.3 0.0 2.3 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KKK22945.1 - 2.8e-08 33.1 0.0 6e-07 28.8 0.0 2.6 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KKK22945.1 - 5.5e-07 29.0 0.0 1.7e-06 27.4 0.0 1.7 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.15 KKK22945.1 - 3.6e-06 26.3 0.0 0.00013 21.2 0.0 2.9 3 1 0 3 3 3 1 Polysaccharide biosynthesis protein KR PF08659.10 KKK22945.1 - 0.0038 17.2 0.0 0.0096 15.9 0.0 1.6 1 1 0 1 1 1 1 KR domain adh_short PF00106.25 KKK22945.1 - 0.022 14.2 0.0 0.035 13.6 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase Sugar_tr PF00083.24 KKK22946.1 - 7.1e-55 186.7 2.6 8e-55 186.5 2.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKK22946.1 - 5e-08 32.3 30.9 3.4e-05 22.9 13.3 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Caps_synth_CapC PF14102.6 KKK22946.1 - 0.27 11.7 5.5 1.1 9.7 1.6 2.6 1 1 2 3 3 3 0 Capsule biosynthesis CapC NTP_transf_9 PF04248.12 KKK22947.1 - 2.1e-30 104.5 0.3 2.3e-30 104.3 0.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF427) MFS_1 PF07690.16 KKK22948.1 - 1.5e-32 112.9 23.5 1.5e-32 112.9 23.5 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF1282 PF06930.12 KKK22948.1 - 0.017 14.9 0.2 0.017 14.9 0.2 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF1282) Sugar_tr PF00083.24 KKK22950.1 - 1.7e-80 271.1 27.5 2e-80 270.9 27.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKK22950.1 - 4.8e-17 61.9 25.1 4.8e-17 61.9 25.1 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily 7TM_GPCR_Sra PF02117.16 KKK22950.1 - 0.014 14.2 1.2 0.031 13.1 0.2 2.0 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Sra DUF2852 PF11014.8 KKK22950.1 - 0.017 15.3 0.1 0.045 13.9 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2852) Phage_holin_2_4 PF16082.5 KKK22950.1 - 0.5 10.1 2.9 0.41 10.4 0.1 2.3 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like DUF3792 PF12670.7 KKK22950.1 - 0.56 10.4 21.1 2.3 8.4 6.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3792) FixS PF03597.15 KKK22950.1 - 0.74 9.6 0.0 0.74 9.6 0.0 3.5 4 0 0 4 4 4 0 Cytochrome oxidase maturation protein cbb3-type APH PF01636.23 KKK22967.1 - 2.9e-12 47.0 0.0 5.4e-12 46.2 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KKK22967.1 - 0.00013 21.6 0.0 0.00024 20.8 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 KKK22967.1 - 0.0043 16.7 0.1 0.034 13.8 0.0 2.0 2 0 0 2 2 2 1 RIO1 family ADH_N PF08240.12 KKK22968.1 - 4.6e-28 97.3 0.1 8.5e-28 96.4 0.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KKK22968.1 - 7.3e-22 77.7 0.8 1.2e-21 77.1 0.8 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KKK22968.1 - 0.00015 22.8 0.1 0.00025 22.1 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 KKK22968.1 - 0.0077 15.6 0.1 0.014 14.8 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 KKK22968.1 - 0.022 14.0 1.2 0.039 13.3 1.2 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain adh_short PF00106.25 KKK22968.1 - 0.11 11.9 0.5 0.26 10.7 0.5 1.6 1 0 0 1 1 1 0 short chain dehydrogenase SNF2_N PF00176.23 KKK22969.1 - 2.7e-64 217.1 1.6 2.7e-64 217.1 1.6 1.8 2 0 0 2 2 2 1 SNF2 family N-terminal domain DBINO PF13892.6 KKK22969.1 - 2e-48 164.1 20.7 2e-48 164.1 20.7 4.9 4 1 1 5 5 5 1 DNA-binding domain Helicase_C PF00271.31 KKK22969.1 - 2.3e-19 69.8 0.0 6.3e-19 68.4 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KKK22969.1 - 2.5e-06 27.6 0.0 2.5e-06 27.6 0.0 2.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KKK22969.1 - 0.00084 19.2 0.0 0.0028 17.4 0.0 2.0 1 0 0 1 1 1 1 DEAD/DEAH box helicase HDA2-3 PF11496.8 KKK22969.1 - 0.016 14.4 0.0 0.11 11.6 0.0 2.4 2 1 0 2 2 2 0 Class II histone deacetylase complex subunits 2 and 3 Aminotran_1_2 PF00155.21 KKK22970.1 - 8.8e-68 229.1 0.0 1.7e-48 165.6 0.0 2.2 1 1 1 2 2 2 2 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KKK22970.1 - 2.1e-05 23.2 0.0 3.7e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 KKK22970.1 - 7.9e-05 22.1 0.2 0.00015 21.2 0.2 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 KKK22970.1 - 0.00069 18.7 0.0 0.0012 17.9 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KKK22970.1 - 0.067 12.5 0.0 0.15 11.3 0.0 1.5 1 0 0 1 1 1 0 Beta-eliminating lyase Preseq_ALAS PF09029.10 KKK22970.1 - 0.38 11.3 2.9 2.1 8.9 2.9 2.2 1 1 0 1 1 1 0 5-aminolevulinate synthase presequence RNA_pol_I_A49 PF06870.12 KKK22971.1 - 6.8e-75 252.3 0.0 2e-74 250.8 0.0 1.6 1 1 0 1 1 1 1 A49-like RNA polymerase I associated factor NST1 PF13945.6 KKK22980.1 - 1.9e-72 243.4 0.7 1.9e-72 243.4 0.7 4.0 3 1 1 4 4 4 1 Salt tolerance down-regulator Ras PF00071.22 KKK22981.1 - 8.1e-36 123.1 0.0 9.3e-36 122.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KKK22981.1 - 3.7e-13 49.8 0.0 7.9e-13 48.7 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase ADH_zinc_N PF00107.26 KKK22981.1 - 0.056 13.4 0.0 9.5 6.2 0.0 2.2 2 0 0 2 2 2 0 Zinc-binding dehydrogenase Fungal_trans PF04082.18 KKK23012.1 - 5.4e-08 32.2 3.0 9.3e-08 31.4 2.5 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK23012.1 - 0.025 14.7 0.7 0.056 13.6 0.7 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Transket_pyr PF02779.24 KKK23016.1 - 2.4e-64 216.3 0.0 4.5e-64 215.4 0.0 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.20 KKK23016.1 - 3.3e-59 200.3 0.0 4.9e-59 199.7 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component OxoGdeHyase_C PF16870.5 KKK23016.1 - 1.1e-57 194.0 0.0 1.8e-57 193.3 0.0 1.3 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal 2-oxogl_dehyd_N PF16078.5 KKK23016.1 - 8.7e-20 70.0 0.4 8.7e-20 70.0 0.4 1.9 2 0 0 2 2 2 1 2-oxoglutarate dehydrogenase N-terminus Aldo_ket_red PF00248.21 KKK23017.1 - 1.7e-51 175.2 0.0 4.9e-51 173.7 0.0 1.6 1 1 0 1 1 1 1 Aldo/keto reductase family Hydrolase_6 PF13344.6 KKK23018.1 - 7.7e-24 83.7 0.0 1.5e-23 82.8 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KKK23018.1 - 9.8e-19 67.2 0.0 2.1e-18 66.2 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 KKK23018.1 - 0.0073 16.6 0.0 2 8.6 0.0 3.2 2 1 1 3 3 3 1 haloacid dehalogenase-like hydrolase Apt1 PF10351.9 KKK23018.1 - 0.16 10.8 0.0 0.34 9.7 0.0 1.4 2 0 0 2 2 2 0 Golgi-body localisation protein domain GATase PF00117.28 KKK23019.1 - 2.8e-38 131.6 0.0 4.8e-38 130.8 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GMP_synt_C PF00958.22 KKK23019.1 - 1.4e-36 124.4 0.0 2.9e-36 123.4 0.0 1.6 1 0 0 1 1 1 1 GMP synthase C terminal domain NAD_synthase PF02540.17 KKK23019.1 - 8.7e-10 38.1 0.0 2.6e-06 26.7 0.1 2.3 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.13 KKK23019.1 - 4.9e-05 23.2 0.1 0.00016 21.5 0.1 1.9 1 1 0 1 1 1 1 Peptidase C26 tRNA_Me_trans PF03054.16 KKK23019.1 - 0.00038 19.4 0.1 0.0012 17.7 0.1 1.7 2 0 0 2 2 2 1 tRNA methyl transferase ThiI PF02568.14 KKK23019.1 - 0.0032 17.1 0.0 0.0071 15.9 0.0 1.5 2 0 0 2 2 2 1 Thiamine biosynthesis protein (ThiI) QueC PF06508.13 KKK23019.1 - 0.0063 16.0 0.0 0.15 11.5 0.0 2.2 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC PAPS_reduct PF01507.19 KKK23019.1 - 0.0079 16.3 0.0 0.014 15.4 0.0 1.4 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family Arginosuc_synth PF00764.19 KKK23019.1 - 0.043 13.1 0.1 0.066 12.5 0.1 1.2 1 0 0 1 1 1 0 Arginosuccinate synthase LRR_4 PF12799.7 KKK23020.1 - 0.0011 19.3 6.6 0.17 12.3 0.1 4.6 4 0 0 4 4 4 1 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KKK23020.1 - 0.0048 16.8 0.0 0.01 15.7 0.0 1.6 1 0 0 1 1 1 1 F-box-like LRR_6 PF13516.6 KKK23020.1 - 0.021 14.8 3.7 36 4.8 0.2 4.6 4 0 0 4 4 4 0 Leucine Rich repeat F-box PF00646.33 KKK23020.1 - 0.031 14.2 1.5 0.24 11.3 1.0 2.7 2 1 0 2 2 2 0 F-box domain LURAP PF14854.6 KKK23020.1 - 0.09 12.7 0.4 0.21 11.5 0.4 1.6 1 0 0 1 1 1 0 Leucine rich adaptor protein LRR_8 PF13855.6 KKK23020.1 - 0.12 12.1 2.4 8.5 6.2 0.1 3.3 3 1 0 3 3 3 0 Leucine rich repeat LRR_1 PF00560.33 KKK23020.1 - 5.3 8.0 8.7 2.5e+02 2.9 0.0 5.7 5 1 0 5 5 5 0 Leucine Rich Repeat BSD PF03909.17 KKK23021.1 - 1.2e-28 98.9 10.8 6e-15 55.0 1.1 3.7 4 0 0 4 4 4 2 BSD domain PH_TFIIH PF08567.11 KKK23021.1 - 8.5e-25 86.9 0.0 2.2e-24 85.6 0.0 1.8 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain Rx_N PF18052.1 KKK23021.1 - 0.0059 16.9 0.5 0.025 14.8 0.2 2.2 2 0 0 2 2 2 1 Rx N-terminal domain PIN_8 PF18476.1 KKK23021.1 - 0.094 12.6 0.1 0.094 12.6 0.1 2.6 2 1 1 3 3 3 0 PIN like domain Pyr_redox_3 PF13738.6 KKK23021.1 - 0.14 11.4 0.1 2.5 7.2 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DctQ PF04290.12 KKK23022.1 - 0.37 10.7 8.1 0.033 14.1 2.6 1.9 2 0 0 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component ING PF12998.7 KKK23023.1 - 1.4e-11 44.8 0.0 2.9e-11 43.8 0.0 1.5 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 KKK23023.1 - 1.7e-06 27.8 7.2 2.8e-06 27.1 7.2 1.3 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 KKK23023.1 - 0.053 13.8 1.6 0.11 12.7 1.6 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain DUF4378 PF14309.6 KKK23023.1 - 0.13 12.6 0.1 0.41 11.0 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4378) PHD_2 PF13831.6 KKK23023.1 - 0.5 10.0 2.7 0.95 9.1 2.7 1.4 1 0 0 1 1 1 0 PHD-finger DDHD PF02862.17 KKK23024.1 - 1.9 8.6 5.9 5.7 7.0 0.9 2.2 2 0 0 2 2 2 0 DDHD domain Hus1 PF04005.12 KKK23031.1 - 7.3e-112 373.2 0.0 8.3e-112 373.0 0.0 1.0 1 0 0 1 1 1 1 Hus1-like protein DUF4552 PF15089.6 KKK23031.1 - 0.0051 15.9 0.2 0.0074 15.4 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4552) APS-reductase_C PF12139.8 KKK23031.1 - 0.07 13.4 0.0 0.17 12.1 0.0 1.7 1 0 0 1 1 1 0 Adenosine-5'-phosphosulfate reductase beta subunit GAS2 PF02187.17 KKK23032.1 - 6.7e-06 26.1 0.1 1.3e-05 25.2 0.1 1.4 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain SNRNP27 PF08648.12 KKK23033.1 - 1.1e-25 89.5 1.4 2.3e-25 88.4 1.4 1.6 1 0 0 1 1 1 1 U4/U6.U5 small nuclear ribonucleoproteins Apt1 PF10351.9 KKK23033.1 - 0.55 9.0 13.7 0.78 8.5 13.7 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain Sec16_C PF12931.7 KKK23034.1 - 2.6e-106 355.7 0.0 3.9e-106 355.1 0.0 1.3 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16_N PF12935.7 KKK23034.1 - 8.7e-70 235.6 22.3 8.7e-70 235.6 22.3 2.7 2 0 0 2 2 2 1 Vesicle coat trafficking protein Sec16 N-terminus Sec16 PF12932.7 KKK23034.1 - 1.6e-34 119.0 0.0 4.1e-34 117.7 0.0 1.8 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region MMtag PF10159.9 KKK23035.1 - 6.1e-34 116.2 3.7 8.7e-34 115.6 3.7 1.2 1 0 0 1 1 1 1 Multiple myeloma tumor-associated Glyco_hydro_63 PF03200.16 KKK23036.1 - 1.5e-169 564.9 0.3 1.3e-168 561.8 0.3 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 63 C-terminal domain Glyco_hydro_63N PF16923.5 KKK23036.1 - 1.2e-87 293.8 0.0 2e-86 289.8 0.0 2.2 2 0 0 2 2 2 1 Glycosyl hydrolase family 63 N-terminal domain DAO PF01266.24 KKK23036.1 - 3.6e-66 224.1 1.1 5.3e-66 223.6 1.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KKK23036.1 - 9e-06 25.8 0.2 2.7e-05 24.3 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KKK23036.1 - 0.0002 20.7 0.1 0.15 11.3 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KKK23036.1 - 0.0049 15.8 0.1 0.036 12.9 0.1 2.0 2 0 0 2 2 2 1 Tryptophan halogenase Pyr_redox PF00070.27 KKK23036.1 - 0.015 15.9 0.4 0.075 13.6 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trehalase PF01204.18 KKK23036.1 - 0.018 13.9 0.2 0.032 13.0 0.2 1.4 1 0 0 1 1 1 0 Trehalase FAD_binding_2 PF00890.24 KKK23036.1 - 0.022 13.9 1.0 0.24 10.4 1.0 2.3 1 1 0 1 1 1 0 FAD binding domain MCRA PF06100.11 KKK23036.1 - 0.09 11.5 0.1 0.14 10.9 0.1 1.2 1 0 0 1 1 1 0 MCRA family Amino_oxidase PF01593.24 KKK23036.1 - 0.11 11.7 0.1 2.1 7.6 0.1 2.3 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Thi4 PF01946.17 KKK23036.1 - 0.13 11.5 0.2 0.22 10.7 0.2 1.3 1 0 0 1 1 1 0 Thi4 family CRT10 PF08728.10 KKK23037.1 - 2.8e-23 82.0 0.0 2.8e-14 52.3 0.0 2.3 2 0 0 2 2 2 2 CRT10 SR-25 PF10500.9 KKK23037.1 - 4.3 6.9 11.7 7.9 6.0 11.7 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Pex14_N PF04695.13 KKK23037.1 - 6.7 7.3 15.5 1.2 9.7 8.2 2.8 2 1 1 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Arb2 PF09757.9 KKK23042.1 - 1.8e-105 351.8 0.2 2.3e-105 351.4 0.2 1.1 1 0 0 1 1 1 1 Arb2 domain Hist_deacetyl PF00850.19 KKK23042.1 - 5.2e-85 285.6 0.0 7.8e-85 285.0 0.0 1.3 1 0 0 1 1 1 1 Histone deacetylase domain Bys1 PF04681.12 KKK23043.1 - 3.1e-11 43.4 0.4 3.7e-11 43.2 0.4 1.0 1 0 0 1 1 1 1 Blastomyces yeast-phase-specific protein NUDIX_2 PF13869.6 KKK23044.1 - 4.8e-82 274.1 0.0 5.7e-82 273.9 0.0 1.0 1 0 0 1 1 1 1 Nucleotide hydrolase Peptidase_M16_M PF16187.5 KKK23045.1 - 2.1e-96 322.5 0.1 4.1e-96 321.5 0.1 1.5 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 Peptidase_M16_C PF05193.21 KKK23045.1 - 6.7e-34 117.5 0.2 2e-23 83.4 0.0 3.8 4 1 1 5 5 5 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 KKK23045.1 - 1.7e-32 112.5 3.8 3.5e-23 82.2 0.4 3.8 3 1 1 4 4 4 2 Insulinase (Peptidase family M16) ERCC4 PF02732.15 KKK23045.1 - 0.017 15.3 0.1 0.063 13.5 0.0 2.0 2 0 0 2 2 2 0 ERCC4 domain Fas_alpha_ACP PF18325.1 KKK23049.1 - 3.5e-56 190.0 0.0 6.3e-56 189.2 0.0 1.4 1 0 0 1 1 1 1 Fatty acid synthase subunit alpha Acyl carrier domain FAS_I_H PF18314.1 KKK23049.1 - 3.6e-37 128.0 0.2 6.5e-37 127.1 0.2 1.4 1 0 0 1 1 1 1 Fatty acid synthase type I helical domain ketoacyl-synt PF00109.26 KKK23049.1 - 7.9e-19 68.2 0.0 1.6e-18 67.2 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 KKK23049.1 - 1.1e-16 61.0 0.0 2.4e-16 59.8 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ACPS PF01648.20 KKK23049.1 - 3.5e-13 49.7 0.0 7.6e-13 48.6 0.0 1.6 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily adh_short_C2 PF13561.6 KKK23049.1 - 0.00057 19.5 0.0 0.00097 18.8 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1729 PF08354.10 KKK23050.1 - 5.1e-143 476.2 0.0 8.2e-143 475.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) Acyl_transf_1 PF00698.21 KKK23050.1 - 8.6e-56 189.7 0.0 7.4e-55 186.7 0.0 2.3 2 1 0 2 2 2 1 Acyl transferase domain MaoC_dehydratas PF01575.19 KKK23050.1 - 1.6e-22 79.3 0.0 3.4e-22 78.3 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain SAT PF16073.5 KKK23050.1 - 7.8e-19 68.4 0.1 1.5e-18 67.4 0.1 1.4 1 0 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis FAS_meander PF17951.1 KKK23050.1 - 1.6e-17 63.7 0.0 3e-17 62.8 0.0 1.4 1 0 0 1 1 1 1 Fatty acid synthase meander beta sheet domain MaoC_dehydrat_N PF13452.6 KKK23050.1 - 7.7e-07 29.3 0.0 1.8e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase FAS_N PF17828.1 KKK23050.1 - 0.017 15.1 0.0 0.039 14.0 0.0 1.6 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta FAD_binding_3 PF01494.19 KKK23051.1 - 2.6e-13 49.9 6.1 8.7e-12 44.9 6.1 2.7 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KKK23051.1 - 0.0015 18.7 0.3 0.0039 17.4 0.3 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KKK23051.1 - 0.003 17.2 0.6 0.0081 15.8 0.4 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase 3HCDH_N PF02737.18 KKK23051.1 - 0.044 13.7 0.2 0.073 12.9 0.2 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.27 KKK23051.1 - 0.049 14.2 1.0 0.21 12.2 0.2 2.5 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase F420_oxidored PF03807.17 KKK23051.1 - 0.15 12.7 0.4 0.38 11.4 0.4 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent SE PF08491.10 KKK23051.1 - 0.22 10.6 0.0 2.9 6.9 0.0 2.1 2 0 0 2 2 2 0 Squalene epoxidase Pyr_redox_2 PF07992.14 KKK23051.1 - 0.28 10.4 1.5 0.84 8.8 0.5 2.1 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase MFS_1 PF07690.16 KKK23052.1 - 1.7e-39 135.8 68.0 3.7e-35 121.5 45.3 3.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KKK23052.1 - 5e-23 81.4 25.2 6.8e-23 80.9 25.2 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KKK23052.1 - 4.6e-17 62.0 5.7 4.6e-17 62.0 5.7 2.4 2 0 0 2 2 2 1 Sugar (and other) transporter Pox_A14 PF05767.12 KKK23052.1 - 0.49 10.6 2.7 4.5 7.5 0.1 2.8 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 Transferase PF02458.15 KKK23053.1 - 5.4e-09 35.2 0.0 2.8e-06 26.3 0.0 2.1 2 0 0 2 2 2 2 Transferase family AraC_binding PF02311.19 KKK23053.1 - 0.034 14.0 0.0 0.062 13.2 0.0 1.4 1 0 0 1 1 1 0 AraC-like ligand binding domain Fungal_trans PF04082.18 KKK23054.1 - 2.8e-16 59.4 0.2 4.2e-16 58.8 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK23054.1 - 1.8e-09 37.5 10.1 3.7e-09 36.5 10.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ketoacyl-synt PF00109.26 KKK23055.1 - 6.3e-57 193.0 0.2 6.9e-46 156.9 0.1 2.6 1 1 1 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 KKK23055.1 - 4.5e-29 100.9 0.0 1.7e-28 99.0 0.0 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.21 KKK23055.1 - 3.5e-28 99.0 0.0 1e-27 97.5 0.0 1.7 1 0 0 1 1 1 1 Acyl transferase domain NAD_binding_4 PF07993.12 KKK23055.1 - 1.6e-25 89.8 0.0 2.7e-25 89.0 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein HTH_51 PF18558.1 KKK23055.1 - 7.6e-25 86.6 0.0 1.9e-24 85.3 0.0 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain PP-binding PF00550.25 KKK23055.1 - 7e-15 55.1 0.3 1.6e-14 54.0 0.3 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_12 PF08242.12 KKK23055.1 - 1.8e-13 51.0 0.0 7.9e-13 49.0 0.0 2.2 2 0 0 2 2 1 1 Methyltransferase domain SAT PF16073.5 KKK23055.1 - 5.6e-10 39.4 0.6 5.9e-06 26.2 0.0 3.4 3 0 0 3 3 3 2 Starter unit:ACP transacylase in aflatoxin biosynthesis Methyltransf_25 PF13649.6 KKK23055.1 - 2.9e-09 37.5 0.0 1e-08 35.8 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Epimerase PF01370.21 KKK23055.1 - 5.2e-09 35.9 0.0 1.2e-08 34.8 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Methyltransf_11 PF08241.12 KKK23055.1 - 2.4e-06 28.1 0.0 9.5e-06 26.2 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KKK23055.1 - 7.9e-05 22.5 0.0 0.00018 21.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KKK23055.1 - 8e-05 22.5 0.0 0.00021 21.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 KKK23055.1 - 0.0064 16.9 0.0 0.015 15.8 0.0 1.6 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Thiolase_N PF00108.23 KKK23055.1 - 0.0098 15.3 0.7 0.017 14.5 0.1 1.7 2 0 0 2 2 2 1 Thiolase, N-terminal domain Ubie_methyltran PF01209.18 KKK23055.1 - 0.021 14.2 0.0 0.04 13.2 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family ACP_syn_III PF08545.10 KKK23055.1 - 0.034 14.0 0.7 0.09 12.6 0.7 1.7 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Cellulase PF00150.18 KKK23056.1 - 2.6e-19 69.7 0.4 3.4e-19 69.3 0.4 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_C PF02836.17 KKK23056.1 - 0.0014 17.8 0.0 0.0028 16.8 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_42 PF02449.15 KKK23056.1 - 0.0015 18.0 0.1 0.015 14.7 0.1 2.0 2 0 0 2 2 2 1 Beta-galactosidase S-methyl_trans PF02574.16 KKK23057.1 - 1.4e-53 182.5 0.0 1.6e-53 182.2 0.0 1.0 1 0 0 1 1 1 1 Homocysteine S-methyltransferase SRR1 PF07985.12 KKK23058.1 - 2.7e-11 43.3 0.0 5.8e-11 42.3 0.0 1.6 1 0 0 1 1 1 1 SRR1 Peptidase_A4 PF01828.17 KKK23059.1 - 2.4e-68 229.7 12.6 3e-68 229.4 12.6 1.1 1 0 0 1 1 1 1 Peptidase A4 family Sugar_tr PF00083.24 KKK23060.1 - 2.1e-137 458.7 22.8 2.4e-137 458.5 22.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKK23060.1 - 8.9e-21 74.2 44.7 4.9e-18 65.2 24.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KKK23060.1 - 0.17 10.4 25.5 0.018 13.7 0.9 2.9 3 1 0 3 3 3 0 MFS/sugar transport protein Fungal_trans PF04082.18 KKK23069.1 - 2.7e-10 39.7 0.1 4.8e-10 38.9 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK23069.1 - 8.9e-07 28.9 10.8 2.4e-06 27.6 10.8 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Phage_rep_O PF04492.13 KKK23069.1 - 0.047 14.3 0.0 0.1 13.2 0.0 1.5 1 0 0 1 1 1 0 Bacteriophage replication protein O Glyco_hydro_43 PF04616.14 KKK23070.1 - 1.7e-28 99.8 0.3 2.2e-28 99.4 0.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Drc1-Sld2 PF11719.8 KKK23071.1 - 4.8e-139 464.8 22.3 7e-139 464.2 22.3 1.2 1 0 0 1 1 1 1 DNA replication and checkpoint protein Tli4_N PF18443.1 KKK23071.1 - 0.12 12.7 0.8 0.36 11.2 0.8 1.8 1 0 0 1 1 1 0 Tle cognate immunity protein 4 N-terminal domain Suc_Fer-like PF06999.12 KKK23072.1 - 4.5e-70 235.5 0.0 5.3e-70 235.3 0.0 1.0 1 0 0 1 1 1 1 Sucrase/ferredoxin-like HAD_SAK_1 PF10307.9 KKK23073.1 - 2e-79 266.1 0.0 2.8e-79 265.7 0.0 1.2 1 0 0 1 1 1 1 HAD domain family 1 in Swiss Army Knife RNA repair proteins API5 PF05918.11 KKK23073.1 - 4 6.1 4.6 6.4 5.5 4.6 1.3 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) zf-RING_2 PF13639.6 KKK23074.1 - 6.8e-10 39.1 4.0 1.1e-09 38.4 4.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 KKK23074.1 - 2.1e-08 33.9 1.6 3.3e-08 33.3 1.6 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KKK23074.1 - 1.7e-07 31.0 4.0 2.7e-07 30.3 4.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KKK23074.1 - 2.7e-07 30.7 1.7 6.7e-07 29.5 1.7 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KKK23074.1 - 3.3e-07 30.1 2.7 5.1e-07 29.4 2.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KKK23074.1 - 0.0021 17.8 3.5 0.0036 17.1 3.5 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 KKK23074.1 - 0.0087 16.1 2.7 0.019 15.0 2.7 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KKK23074.1 - 0.16 11.9 1.6 0.32 11.0 1.6 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KKK23074.1 - 0.24 11.6 4.5 0.44 10.7 4.5 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_11 PF17123.5 KKK23074.1 - 0.25 11.1 1.7 0.56 10.0 1.7 1.6 1 0 0 1 1 1 0 RING-like zinc finger zf-MIZ PF02891.20 KKK23074.1 - 0.53 10.1 2.3 0.96 9.2 2.3 1.4 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger Nnf1 PF03980.14 KKK23104.1 - 3.6e-29 101.4 2.4 3.6e-29 101.4 2.4 2.5 2 1 1 3 3 3 1 Nnf1 Spc42p PF11544.8 KKK23104.1 - 0.02 14.9 1.0 0.07 13.1 0.1 2.4 2 1 1 3 3 3 0 Spindle pole body component Spc42p TPR_17 PF13431.6 KKK23105.1 - 0.00055 20.1 0.5 1 9.9 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 KKK23105.1 - 0.022 14.5 2.8 0.25 11.1 0.0 3.8 4 0 0 4 4 4 0 TPR repeat TPR_12 PF13424.6 KKK23105.1 - 0.8 10.0 9.9 3.7 7.9 0.1 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat AAA PF00004.29 KKK23107.1 - 3.4e-48 163.4 0.0 5.5e-43 146.6 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KKK23107.1 - 5.1e-06 26.2 3.4 0.0072 16.1 0.0 2.9 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 KKK23107.1 - 0.00012 22.5 0.0 0.022 15.2 0.0 3.0 2 0 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 KKK23107.1 - 0.00013 21.7 0.0 0.00041 20.1 0.0 1.8 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Parvo_NS1 PF01057.17 KKK23107.1 - 0.00059 19.0 0.0 0.00098 18.3 0.0 1.2 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 RNA_helicase PF00910.22 KKK23107.1 - 0.0027 18.1 0.0 0.015 15.7 0.0 2.3 3 0 0 3 3 2 1 RNA helicase AAA_2 PF07724.14 KKK23107.1 - 0.0038 17.3 0.0 0.0093 16.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) TIP49 PF06068.13 KKK23107.1 - 0.0075 15.5 0.0 0.012 14.8 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_22 PF13401.6 KKK23107.1 - 0.0083 16.4 0.0 0.044 14.1 0.0 2.3 1 1 1 2 2 2 1 AAA domain IstB_IS21 PF01695.17 KKK23107.1 - 0.0097 15.7 0.0 0.019 14.7 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_25 PF13481.6 KKK23107.1 - 0.011 15.3 0.0 0.041 13.5 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KKK23107.1 - 0.023 14.2 0.0 0.041 13.4 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Mg_chelatase PF01078.21 KKK23107.1 - 0.028 13.8 0.1 0.056 12.8 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ATPase PF06745.13 KKK23107.1 - 0.041 13.2 0.0 0.084 12.2 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_18 PF13238.6 KKK23107.1 - 0.041 14.4 0.0 0.12 13.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 KKK23107.1 - 0.045 13.7 0.0 0.13 12.2 0.0 1.9 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) TsaE PF02367.17 KKK23107.1 - 0.073 13.1 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PhoH PF02562.16 KKK23107.1 - 0.078 12.4 0.0 0.21 11.0 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein AAA_28 PF13521.6 KKK23107.1 - 0.1 12.8 0.0 0.32 11.2 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_33 PF13671.6 KKK23107.1 - 0.11 12.6 0.0 0.45 10.7 0.0 2.1 2 0 0 2 2 1 0 AAA domain Choline_transpo PF04515.12 KKK23108.1 - 3.1e-81 273.1 26.2 3.1e-81 273.1 26.2 2.3 2 0 0 2 2 2 1 Plasma-membrane choline transporter RabGAP-TBC PF00566.18 KKK23108.1 - 2.3e-34 118.9 0.1 2.6e-30 105.7 0.1 2.7 2 0 0 2 2 2 2 Rab-GTPase-TBC domain Fructosamin_kin PF03881.14 KKK23108.1 - 0.0098 15.1 0.3 0.045 12.9 0.0 2.0 2 0 0 2 2 2 1 Fructosamine kinase Questin_oxidase PF14027.6 KKK23109.1 - 7.4e-93 311.8 4.4 8.7e-93 311.6 4.4 1.0 1 0 0 1 1 1 1 Questin oxidase-like AA_permease_2 PF13520.6 KKK23110.1 - 2e-45 155.4 59.0 2.4e-45 155.2 59.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KKK23110.1 - 5.8e-13 48.3 51.9 2.1e-12 46.4 51.9 2.2 1 1 0 1 1 1 1 Amino acid permease TauD PF02668.16 KKK23111.1 - 9.9e-08 32.1 0.1 1.5e-07 31.5 0.1 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family MFS_1 PF07690.16 KKK23112.1 - 6.9e-25 87.7 20.3 8.4e-25 87.4 20.3 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KKK23113.1 - 2e-07 30.3 1.2 2.4e-07 30.0 1.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter V-SNARE_C PF12352.8 KKK23113.1 - 0.015 15.6 0.0 0.022 15.1 0.0 1.2 1 0 0 1 1 1 0 Snare region anchored in the vesicle membrane C-terminus TauD PF02668.16 KKK23114.1 - 6.7e-24 85.1 0.0 8e-24 84.9 0.0 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family HECT_2 PF09814.9 KKK23115.1 - 1.7e-104 349.7 0.1 1.9e-104 349.5 0.1 1.0 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding SAVED PF18145.1 KKK23115.1 - 0.076 12.8 0.7 0.15 11.9 0.7 1.4 1 0 0 1 1 1 0 SMODS-associated and fused to various effectors sensor domain PFK PF00365.20 KKK23138.1 - 9.3e-193 638.8 0.5 4e-105 351.2 0.0 2.1 2 0 0 2 2 2 2 Phosphofructokinase DAGK_cat PF00781.24 KKK23138.1 - 0.009 15.6 0.0 0.14 11.8 0.1 2.6 2 0 0 2 2 2 1 Diacylglycerol kinase catalytic domain ISN1 PF06437.11 KKK23139.1 - 1.2e-199 663.4 0.0 1.3e-199 663.2 0.0 1.0 1 0 0 1 1 1 1 IMP-specific 5'-nucleotidase S36_mt PF10937.8 KKK23154.1 - 3e-38 131.9 0.2 3.5e-38 131.7 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S36, mitochondrial DUF647 PF04884.14 KKK23155.1 - 3e-107 357.7 4.0 4e-107 357.3 4.0 1.2 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis M20_dimer PF07687.14 KKK23157.1 - 1.9e-16 59.9 0.1 3.7e-16 59.0 0.1 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.28 KKK23157.1 - 1.8e-07 31.1 0.4 2.9e-06 27.1 0.0 2.2 2 1 0 2 2 2 1 Peptidase family M20/M25/M40 Med18 PF09637.10 KKK23158.1 - 4.1e-64 216.8 0.0 4.6e-64 216.6 0.0 1.0 1 0 0 1 1 1 1 Med18 protein RGS PF00615.19 KKK23159.1 - 6.4e-12 45.8 0.0 9.9e-12 45.2 0.0 1.2 1 0 0 1 1 1 1 Regulator of G protein signaling domain PNK3P PF08645.11 KKK23160.1 - 2.4e-55 186.6 0.1 4.3e-55 185.8 0.1 1.4 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.6 KKK23160.1 - 1.3e-29 103.2 0.0 4.4e-27 95.0 0.0 2.6 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.10 KKK23160.1 - 1e-06 28.5 0.0 0.0044 16.5 0.0 2.3 1 1 1 2 2 2 2 Chromatin associated protein KTI12 Zeta_toxin PF06414.12 KKK23160.1 - 0.037 13.3 0.0 3.2 7.0 0.0 2.4 1 1 1 2 2 2 0 Zeta toxin Questin_oxidase PF14027.6 KKK23172.1 - 5.4e-82 276.1 0.1 7.1e-82 275.7 0.1 1.1 1 0 0 1 1 1 1 Questin oxidase-like NAD_binding_10 PF13460.6 KKK23172.1 - 4e-15 56.2 0.0 8.7e-15 55.1 0.0 1.6 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KKK23172.1 - 0.001 18.7 0.1 0.0023 17.5 0.0 1.6 2 0 0 2 2 2 1 NmrA-like family 3Beta_HSD PF01073.19 KKK23172.1 - 0.007 15.4 0.6 0.013 14.5 0.1 1.7 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KKK23172.1 - 0.12 11.8 0.0 0.34 10.4 0.0 1.8 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 KKK23172.1 - 0.16 12.5 0.0 2.6 8.5 0.0 2.6 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain AMP-binding PF00501.28 KKK23173.1 - 9.2e-47 159.6 0.0 1.2e-46 159.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme GST_C PF00043.25 KKK23175.1 - 5.5e-09 36.1 0.0 1.1e-08 35.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KKK23175.1 - 2.7e-07 30.5 0.1 4.5e-07 29.8 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KKK23175.1 - 2.7e-07 30.7 0.0 4.5e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KKK23175.1 - 3.2e-07 30.6 0.0 6.1e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain PNP_UDP_1 PF01048.20 KKK23176.1 - 2.5e-07 30.2 1.0 9.6e-07 28.3 1.0 1.8 1 1 0 1 1 1 1 Phosphorylase superfamily TRF PF08558.10 KKK23177.1 - 1e-92 310.1 2.5 1.8e-92 309.3 2.5 1.4 1 0 0 1 1 1 1 Telomere repeat binding factor (TRF) TFIID_30kDa PF03540.13 KKK23177.1 - 3.8e-22 78.0 0.1 9.8e-22 76.7 0.1 1.8 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit Myb_DNA-binding PF00249.31 KKK23177.1 - 0.00086 19.5 0.0 0.0016 18.6 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain eIF-3_zeta PF05091.12 KKK23177.1 - 1 8.2 15.3 2 7.3 15.3 1.4 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) EOS1 PF12326.8 KKK23177.1 - 1.4 8.8 5.3 3.8 7.4 5.3 1.7 1 0 0 1 1 1 0 N-glycosylation protein FAM60A PF15396.6 KKK23177.1 - 3.9 7.4 7.0 16 5.4 7.0 2.1 1 0 0 1 1 1 0 Protein Family FAM60A DUF2981 PF11200.8 KKK23177.1 - 6.6 6.4 9.1 23 4.6 9.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) SBF PF01758.16 KKK23178.1 - 8.4e-52 175.7 7.5 8.4e-52 175.7 7.5 2.5 2 2 1 3 3 3 1 Sodium Bile acid symporter family IPK PF03770.16 KKK23179.1 - 2.7e-60 203.6 0.0 3.8e-60 203.1 0.0 1.2 1 0 0 1 1 1 1 Inositol polyphosphate kinase TPPII_N PF12583.8 KKK23179.1 - 1.8 9.1 6.8 5.5 7.6 6.6 1.7 2 0 0 2 2 2 0 Tripeptidyl peptidase II N terminal Arb1 PF09692.10 KKK23180.1 - 7.7e-130 433.7 0.0 9e-130 433.4 0.0 1.0 1 0 0 1 1 1 1 Argonaute siRNA chaperone (ARC) complex subunit Arb1 DUF600 PF04634.12 KKK23180.1 - 0.00074 19.6 0.0 0.0014 18.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF600 FAD_binding_3 PF01494.19 KKK23181.1 - 1.2e-09 37.9 0.1 3.5e-06 26.5 0.0 3.2 3 0 0 3 3 3 2 FAD binding domain DAO PF01266.24 KKK23181.1 - 0.00013 21.7 0.0 0.00022 21.0 0.0 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KKK23181.1 - 0.0005 20.1 0.0 0.032 14.2 0.0 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KKK23181.1 - 0.0027 17.9 0.8 0.0067 16.6 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KKK23181.1 - 0.0036 16.6 0.0 0.02 14.1 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMN_red PF03358.15 KKK23182.1 - 2.2e-22 79.5 0.0 3.3e-22 78.9 0.0 1.3 1 0 0 1 1 1 1 NADPH-dependent FMN reductase LMWPc PF01451.21 KKK23183.1 - 2.4e-21 76.6 0.0 3.3e-21 76.1 0.0 1.2 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase Ribosomal_S19 PF00203.21 KKK23184.1 - 6e-25 86.9 0.0 7.3e-25 86.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S19 ADH_zinc_N PF00107.26 KKK23185.1 - 4.2e-26 91.5 0.0 9e-26 90.4 0.0 1.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KKK23185.1 - 8.6e-23 81.9 0.0 1.6e-22 81.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KKK23185.1 - 5.3e-09 35.9 0.0 2.1e-08 34.0 0.0 1.9 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 KKK23185.1 - 0.00021 21.1 0.0 0.00054 19.8 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase Cpn10 PF00166.21 KKK23185.1 - 0.018 15.1 0.0 0.21 11.7 0.0 2.5 2 0 0 2 2 2 0 Chaperonin 10 Kd subunit OPT PF03169.15 KKK23186.1 - 6.2e-117 391.8 40.5 7.3e-117 391.5 40.5 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Beta-lactamase PF00144.24 KKK23187.1 - 4.1e-29 101.9 1.1 4e-28 98.6 1.1 2.0 1 1 0 1 1 1 1 Beta-lactamase IF-2B PF01008.17 KKK23188.1 - 7.8e-48 163.1 0.0 2.1e-47 161.7 0.0 1.6 1 1 0 1 1 1 1 Initiation factor 2 subunit family Adaptin_N PF01602.20 KKK23189.1 - 5.9e-105 351.8 0.0 9.5e-105 351.1 0.0 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KKK23189.1 - 3.5e-16 59.7 0.0 1.1e-12 48.3 0.0 3.5 2 2 2 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KKK23189.1 - 3.6e-09 36.9 2.4 0.0015 18.9 0.0 5.1 4 1 1 5 5 5 3 HEAT repeats HEAT PF02985.22 KKK23189.1 - 1.6e-07 31.0 0.2 0.048 13.9 0.0 5.0 6 0 0 6 6 6 2 HEAT repeat Arm PF00514.23 KKK23189.1 - 0.0036 17.3 2.8 0.97 9.6 0.1 4.9 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat Cohesin_HEAT PF12765.7 KKK23189.1 - 0.021 15.1 0.2 0.47 10.8 0.0 3.0 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion RICTOR_N PF14664.6 KKK23189.1 - 0.022 13.8 0.0 2.7 6.9 0.0 2.6 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR, N-term MOR2-PAG1_N PF14222.6 KKK23189.1 - 0.038 12.9 0.1 0.068 12.1 0.1 1.3 1 0 0 1 1 1 0 Cell morphogenesis N-terminal Cnd3 PF12719.7 KKK23189.1 - 0.37 10.0 4.3 0.41 9.8 0.1 2.9 3 1 0 4 4 4 0 Nuclear condensing complex subunits, C-term domain Rho_GDI PF02115.17 KKK23190.1 - 2.3e-61 207.0 0.0 2.7e-61 206.7 0.0 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor KilA-N PF04383.13 KKK23191.1 - 0.00039 20.2 0.0 0.0038 17.1 0.0 2.3 1 1 0 1 1 1 1 KilA-N domain Nuf2 PF03800.14 KKK23192.1 - 3.3e-43 147.2 0.0 8.9e-43 145.7 0.0 1.8 1 0 0 1 1 1 1 Nuf2 family DHR10 PF18595.1 KKK23192.1 - 4.1e-35 120.3 23.1 4.1e-35 120.3 23.1 3.5 3 0 0 3 3 3 2 Designed helical repeat protein 10 domain Apolipoprotein PF01442.18 KKK23192.1 - 0.0026 17.7 24.1 0.0026 17.7 24.1 2.5 1 1 1 2 2 2 1 Apolipoprotein A1/A4/E domain Bacillus_HBL PF05791.11 KKK23192.1 - 0.83 9.5 18.3 0.16 11.8 3.5 3.4 1 1 1 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) MobC PF05713.11 KKK23192.1 - 1.6 9.2 4.7 3.5 8.2 0.5 3.6 3 0 0 3 3 3 0 Bacterial mobilisation protein (MobC) Laminin_II PF06009.12 KKK23192.1 - 2.8 7.9 35.7 1.8 8.6 11.5 3.4 1 1 1 3 3 3 0 Laminin Domain II Spc7 PF08317.11 KKK23192.1 - 7.8 5.3 56.9 2.5 6.9 17.3 3.1 1 1 2 3 3 3 0 Spc7 kinetochore protein Metallophos PF00149.28 KKK23194.1 - 3.9e-36 125.5 0.2 5.5e-36 125.0 0.2 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KKK23194.1 - 0.014 15.8 0.3 0.044 14.2 0.3 1.9 1 1 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain Metallophos_2 PF12850.7 KKK23194.1 - 0.11 12.7 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain CLP1_N PF16573.5 KKK23195.1 - 1.3e-33 115.1 0.0 2.4e-33 114.2 0.0 1.4 1 0 0 1 1 1 1 N-terminal beta-sandwich domain of polyadenylation factor CLP1_P PF16575.5 KKK23195.1 - 4.7e-30 104.8 0.0 4.1e-29 101.7 0.0 2.4 1 1 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop Clp1 PF06807.14 KKK23195.1 - 8.8e-23 80.9 0.0 4.6e-22 78.6 0.0 2.1 1 1 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 ATP_bind_1 PF03029.17 KKK23195.1 - 6.9e-05 22.8 0.0 0.00029 20.7 0.0 1.8 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.23 KKK23195.1 - 0.0015 18.6 0.0 0.0077 16.3 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_35 PF14516.6 KKK23195.1 - 0.023 13.6 0.0 0.034 13.0 0.0 1.1 1 0 0 1 1 1 0 AAA-like domain SRPRB PF09439.10 KKK23195.1 - 0.15 11.5 0.0 0.29 10.6 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Polysacc_deac_1 PF01522.21 KKK23196.1 - 2e-20 72.9 0.0 4.1e-19 68.7 0.0 2.2 2 0 0 2 2 2 1 Polysaccharide deacetylase Ribonuc_2-5A PF06479.12 KKK23196.1 - 0.037 14.2 0.0 12 6.1 0.0 2.4 2 0 0 2 2 2 0 Ribonuclease 2-5A Polysacc_deac_2 PF04748.13 KKK23196.1 - 0.079 12.1 0.0 0.23 10.6 0.0 1.8 1 1 0 1 1 1 0 Divergent polysaccharide deacetylase Presenilin PF01080.17 KKK23196.1 - 0.66 8.7 2.4 0.9 8.2 2.4 1.2 1 0 0 1 1 1 0 Presenilin Menin PF05053.13 KKK23196.1 - 2.2 6.6 10.6 3 6.1 10.6 1.1 1 0 0 1 1 1 0 Menin LAP1C PF05609.12 KKK23196.1 - 3.5 6.6 7.4 4.6 6.2 7.4 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Ras PF00071.22 KKK23198.1 - 3.2e-51 173.2 0.6 2.3e-50 170.4 0.6 1.9 1 1 0 1 1 1 1 Ras family Roc PF08477.13 KKK23198.1 - 4.5e-18 65.6 0.1 4e-17 62.5 0.1 2.1 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKK23198.1 - 0.00083 18.8 0.1 0.0042 16.5 0.0 1.9 2 0 0 2 2 2 1 ADP-ribosylation factor family FeoB_N PF02421.18 KKK23198.1 - 0.025 14.1 0.2 0.58 9.7 0.0 2.5 2 1 1 3 3 3 0 Ferrous iron transport protein B Septin PF00735.18 KKK23198.1 - 0.12 11.7 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 Septin SRPRB PF09439.10 KKK23198.1 - 0.12 11.8 0.0 0.62 9.5 0.0 1.9 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_25 PF13481.6 KKK23198.1 - 0.12 11.9 0.2 0.32 10.6 0.1 1.8 2 1 0 2 2 2 0 AAA domain HAD_2 PF13419.6 KKK23199.1 - 1.9e-05 24.8 0.0 2.1e-05 24.7 0.0 1.3 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KKK23199.1 - 0.00011 22.6 0.0 0.00048 20.5 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KKK23199.1 - 0.00064 19.7 0.0 0.0011 19.0 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Ribosomal_S28e PF01200.18 KKK23214.1 - 2.8e-31 107.3 2.0 3.1e-31 107.2 2.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e TPR_MLP1_2 PF07926.12 KKK23223.1 - 5e-33 113.9 35.9 5e-33 113.9 35.9 17.6 9 5 7 17 17 17 5 TPR/MLP1/MLP2-like protein KASH_CCD PF14662.6 KKK23223.1 - 0.002 18.0 31.2 0.002 18.0 31.2 14.2 7 3 6 13 13 13 2 Coiled-coil region of CCDC155 or KASH CENP-F_leu_zip PF10473.9 KKK23223.1 - 0.0072 16.4 5.0 0.0072 16.4 5.0 15.9 7 3 10 17 17 17 6 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 APC_N_CC PF16689.5 KKK23223.1 - 0.063 13.3 0.0 0.063 13.3 0.0 11.1 13 0 0 13 13 13 0 Coiled-coil N-terminus of APC, dimerisation domain Wzy_C_2 PF11846.8 KKK23223.1 - 1.3 8.9 5.6 0.86 9.5 2.2 2.7 2 0 0 2 2 2 0 Virulence factor membrane-bound polymerase, C-terminal Surfac_D-trimer PF09006.11 KKK23223.1 - 9 6.3 8.7 28 4.7 0.0 5.1 5 0 0 5 5 5 0 Lung surfactant protein D coiled-coil trimerisation Ank_2 PF12796.7 KKK23224.1 - 8.5e-38 128.8 5.9 1.5e-14 54.4 0.1 4.1 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KKK23224.1 - 1.6e-27 95.5 10.0 1.8e-08 34.7 0.2 5.1 5 0 0 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KKK23224.1 - 1.2e-26 89.8 10.8 0.00055 20.2 0.1 8.4 8 0 0 8 8 8 5 Ankyrin repeat Ank PF00023.30 KKK23224.1 - 5.1e-25 86.8 25.1 1.2e-05 25.5 0.1 8.2 7 1 1 8 8 8 7 Ankyrin repeat Ank_5 PF13857.6 KKK23224.1 - 1.6e-23 82.5 19.4 1.5e-05 25.1 0.1 8.0 2 2 7 9 9 9 6 Ankyrin repeats (many copies) RVP PF00077.20 KKK23224.1 - 0.14 12.5 0.3 60 4.0 0.0 4.1 5 0 0 5 5 5 0 Retroviral aspartyl protease DHBP_synthase PF00926.19 KKK23225.1 - 6.2e-79 264.0 0.0 7.4e-79 263.7 0.0 1.1 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase TFA2_Winged_2 PF18121.1 KKK23226.1 - 3.7e-22 77.8 0.4 9.7e-22 76.4 0.4 1.8 1 0 0 1 1 1 1 TFA2 Winged helix domain 2 TFIIE_beta PF02186.15 KKK23226.1 - 1.5e-20 73.2 0.0 6.9e-20 71.1 0.0 2.1 2 0 0 2 2 2 1 TFIIE beta subunit core domain DAG_kinase_N PF14513.6 KKK23226.1 - 0.2 11.8 1.5 0.82 9.9 0.1 2.1 2 0 0 2 2 2 0 Diacylglycerol kinase N-terminus DUF4419 PF14388.6 KKK23227.1 - 2.4e-87 293.2 0.1 3.1e-87 292.8 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4419) Ribosomal_L22e PF01776.17 KKK23230.1 - 2.1e-13 50.6 0.0 2.4e-13 50.4 0.0 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family E1_dh PF00676.20 KKK23256.1 - 2.3e-114 381.4 0.1 2.8e-114 381.1 0.1 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 KKK23256.1 - 0.00046 19.5 0.1 0.00086 18.6 0.1 1.4 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase DUF829 PF05705.14 KKK23264.1 - 3e-55 187.7 0.0 3.5e-55 187.5 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) RETICULATA-like PF11891.8 KKK23264.1 - 0.0098 15.7 0.0 0.014 15.2 0.0 1.2 1 0 0 1 1 1 1 Protein RETICULATA-related Rad51 PF08423.11 KKK23265.1 - 1.3e-42 145.8 0.0 1.1e-39 136.3 0.0 2.1 2 0 0 2 2 2 2 Rad51 ATPase PF06745.13 KKK23265.1 - 6.8e-09 35.4 0.0 1.6e-08 34.2 0.0 1.6 1 1 0 1 1 1 1 KaiC AAA_25 PF13481.6 KKK23265.1 - 3.2e-08 33.4 0.0 6.5e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain RecA PF00154.21 KKK23265.1 - 0.0065 16.0 0.0 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 recA bacterial DNA recombination protein Pox_A32 PF04665.12 KKK23265.1 - 0.039 13.4 0.2 0.066 12.7 0.2 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein DHR10 PF18595.1 KKK23266.1 - 0.056 13.5 4.7 0.16 12.0 4.7 1.8 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain Velvet PF11754.8 KKK23267.1 - 3.1e-50 171.4 0.1 2e-31 109.8 0.0 3.9 2 2 1 3 3 3 2 Velvet factor Ank_5 PF13857.6 KKK23268.1 - 4.9e-11 42.6 0.5 2.1e-07 31.1 0.2 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) TIG PF01833.24 KKK23268.1 - 2.7e-10 40.2 0.4 1.2e-09 38.1 0.2 2.2 2 0 0 2 2 2 1 IPT/TIG domain Ank_4 PF13637.6 KKK23268.1 - 3.7e-07 30.6 0.4 7.1e-06 26.5 0.2 2.5 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 KKK23268.1 - 6.5e-07 29.5 7.5 0.0012 19.3 1.1 2.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 KKK23268.1 - 9.2e-07 29.4 0.0 1.7e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KKK23268.1 - 4.3e-05 23.6 0.3 0.059 14.0 0.2 2.6 2 0 0 2 2 2 2 Ankyrin repeat TMEM51 PF15345.6 KKK23268.1 - 0.028 14.3 0.4 0.028 14.3 0.4 2.7 3 0 0 3 3 3 0 Transmembrane protein 51 Glyco_hydro_61 PF03443.14 KKK23269.1 - 2.1e-68 230.3 0.4 2.1e-68 230.3 0.4 1.7 2 0 0 2 2 2 1 Glycosyl hydrolase family 61 DUF966 PF06136.13 KKK23269.1 - 0.11 12.2 10.5 0.14 11.8 10.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) SOG2 PF10428.9 KKK23269.1 - 0.21 10.8 20.9 0.25 10.5 20.9 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein GREB1 PF15782.5 KKK23269.1 - 9.3 3.2 12.0 12 2.9 12.0 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer FA_desaturase PF00487.24 KKK23270.1 - 6.8e-23 81.8 19.6 1.5e-22 80.7 19.6 1.6 1 1 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 KKK23270.1 - 3.6e-05 24.0 0.0 9.1e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) MARVEL PF01284.23 KKK23270.1 - 0.66 10.0 5.1 6.4 6.8 3.2 2.3 2 0 0 2 2 2 0 Membrane-associating domain TRAPPC10 PF12584.8 KKK23271.1 - 9.7e-41 139.1 0.0 1.8e-40 138.2 0.0 1.5 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 Glyco_hydro_43 PF04616.14 KKK23272.1 - 1.4e-52 178.8 6.4 7.1e-29 101.0 0.7 2.2 1 1 1 2 2 2 2 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 KKK23272.1 - 5.7e-12 45.8 0.0 9.1e-12 45.1 0.0 1.3 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain SUI1 PF01253.22 KKK23273.1 - 1.5e-21 76.7 0.1 2.9e-21 75.8 0.1 1.5 1 0 0 1 1 1 1 Translation initiation factor SUI1 Pkinase PF00069.25 KKK23273.1 - 4.8e-09 36.0 0.0 1.3e-08 34.6 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pre-PUA PF17832.1 KKK23273.1 - 5e-09 36.7 0.2 1.4e-07 32.1 0.1 2.9 2 1 0 2 2 2 1 Pre-PUA-like domain Pkinase_Tyr PF07714.17 KKK23273.1 - 8.5e-06 25.2 0.0 1.7e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KKK23273.1 - 0.0075 15.6 0.4 0.021 14.2 0.1 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KKK23273.1 - 0.013 15.4 0.8 0.013 15.4 0.8 2.3 3 0 0 3 3 3 0 Phosphotransferase enzyme family FTA2 PF13095.6 KKK23273.1 - 0.04 13.5 0.1 0.077 12.6 0.1 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 KKK23273.1 - 0.045 13.1 0.0 0.34 10.2 0.0 2.0 2 0 0 2 2 2 0 Kinase-like Chitin_synth_2 PF03142.15 KKK23274.1 - 7.4e-24 84.3 8.0 2.1e-22 79.4 1.1 2.7 2 1 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 KKK23274.1 - 2.7e-14 53.6 5.2 2.7e-14 53.6 5.2 2.6 2 2 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KKK23274.1 - 1.3e-10 41.5 0.1 5.2e-10 39.6 0.1 1.8 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KKK23274.1 - 0.074 12.9 0.1 7.8 6.3 0.1 2.4 2 0 0 2 2 2 0 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 KKK23274.1 - 0.14 11.7 0.7 5.1 6.5 0.7 2.4 1 1 0 1 1 1 0 Glycosyl transferase family 21 Benyvirus_14KDa PF07255.11 KKK23274.1 - 0.15 12.3 0.3 0.3 11.3 0.3 1.4 1 0 0 1 1 1 0 Benyvirus 14KDa protein Dabb PF07876.12 KKK23275.1 - 8.5e-12 45.5 0.0 9.6e-12 45.4 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain La PF05383.17 KKK23276.1 - 8e-22 77.1 0.1 1.3e-21 76.3 0.1 1.4 1 0 0 1 1 1 1 La domain RRM_1 PF00076.22 KKK23276.1 - 1.7e-07 30.9 0.1 7.6e-07 28.9 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FDF PF09532.10 KKK23277.1 - 1.8e-22 80.2 2.6 3.3e-22 79.3 1.9 1.7 2 0 0 2 2 2 1 FDF domain LSM14 PF12701.7 KKK23278.1 - 2.7e-28 97.9 0.0 3.8e-28 97.4 0.0 1.2 1 0 0 1 1 1 1 Scd6-like Sm domain SM-ATX PF14438.6 KKK23278.1 - 7.8e-06 25.9 0.0 1.3e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM PF01423.22 KKK23278.1 - 0.11 12.2 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 LSM domain WD40 PF00400.32 KKK23279.1 - 1.8e-22 79.2 4.5 4.4e-06 27.3 0.1 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKK23279.1 - 3e-07 30.6 0.1 0.14 12.5 0.0 4.1 2 2 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 KKK23279.1 - 8.1e-05 21.5 0.0 0.74 8.5 0.0 3.2 1 1 2 3 3 3 3 Nup133 N terminal like Nup160 PF11715.8 KKK23279.1 - 0.00029 19.6 0.0 0.15 10.7 0.0 2.8 3 0 0 3 3 3 2 Nucleoporin Nup120/160 YbaB_DNA_bd PF02575.16 KKK23279.1 - 0.052 13.8 0.0 14 6.0 0.0 2.4 2 0 0 2 2 2 0 YbaB/EbfC DNA-binding family SGL PF08450.12 KKK23279.1 - 0.12 11.9 1.5 5.9 6.4 0.0 3.1 1 1 2 3 3 3 0 SMP-30/Gluconolactonase/LRE-like region Thioredox_DsbH PF03190.15 KKK23280.1 - 1.1e-72 243.4 0.0 2.9e-72 241.9 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function, DUF255 Thioredoxin_7 PF13899.6 KKK23280.1 - 1.4e-05 25.2 0.0 2.5e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like Glyco_hydro_9 PF00759.19 KKK23280.1 - 0.005 16.3 0.0 0.0083 15.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 Glyco_hydro_88 PF07470.13 KKK23280.1 - 0.04 13.0 0.1 1.2 8.1 0.0 2.8 2 1 1 3 3 3 0 Glycosyl Hydrolase Family 88 CAP PF00188.26 KKK23281.1 - 4.2e-18 66.4 1.4 4.2e-18 66.4 1.4 2.2 2 0 0 2 2 2 1 Cysteine-rich secretory protein family Macoilin PF09726.9 KKK23281.1 - 7.2 5.0 14.4 8.6 4.8 14.4 1.1 1 0 0 1 1 1 0 Macoilin family Carn_acyltransf PF00755.20 KKK23282.1 - 1.9e-212 707.0 0.0 4.3e-212 705.9 0.0 1.5 1 1 0 1 1 1 1 Choline/Carnitine o-acyltransferase zf-BED PF02892.15 KKK23285.1 - 0.0032 17.5 2.7 0.024 14.6 0.1 2.6 2 0 0 2 2 2 1 BED zinc finger Phage_clamp_A PF16790.5 KKK23285.1 - 0.063 13.7 0.0 0.11 12.9 0.0 1.3 1 0 0 1 1 1 0 Bacteriophage clamp loader A subunit Nbl1_Borealin_N PF10444.9 KKK23286.1 - 1.9e-19 69.0 5.8 3.7e-19 68.1 5.8 1.5 1 0 0 1 1 1 1 Nbl1 / Borealin N terminal Sybindin PF04099.12 KKK23287.1 - 3.8e-34 117.7 0.1 6.9e-20 71.4 0.0 2.3 2 0 0 2 2 2 2 Sybindin-like family Sedlin_N PF04628.13 KKK23287.1 - 0.002 18.2 0.1 0.0039 17.3 0.1 1.3 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region YpzG PF14139.6 KKK23287.1 - 0.6 10.3 4.1 0.19 11.9 0.8 1.8 2 0 0 2 2 2 0 YpzG-like protein zf-C2H2_4 PF13894.6 KKK23287.1 - 1.1 10.2 11.3 1.2 10.2 1.3 3.8 3 0 0 3 3 3 0 C2H2-type zinc finger VWA_2 PF13519.6 KKK23288.1 - 6.6e-21 75.0 0.1 2.2e-20 73.3 0.0 1.8 2 0 0 2 2 2 1 von Willebrand factor type A domain Ssl1 PF04056.14 KKK23288.1 - 3.9e-05 23.5 0.1 5.8e-05 23.0 0.1 1.2 1 0 0 1 1 1 1 Ssl1-like VWA PF00092.28 KKK23288.1 - 0.00066 20.0 0.3 0.001 19.4 0.3 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain UIM PF02809.20 KKK23288.1 - 0.032 14.1 0.1 0.11 12.4 0.1 2.0 1 0 0 1 1 1 0 Ubiquitin interaction motif DUF1194 PF06707.11 KKK23288.1 - 0.13 11.4 0.0 0.21 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1194) Alpha-L-AF_C PF06964.12 KKK23289.1 - 1.7e-21 77.1 0.1 3.1e-21 76.2 0.1 1.5 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminal domain Glyco_hydro_79C PF16862.5 KKK23289.1 - 0.041 14.8 0.2 0.16 12.8 0.2 2.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 79 C-terminal beta domain MGDG_synth PF06925.11 KKK23289.1 - 0.13 12.4 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 Monogalactosyldiacylglycerol (MGDG) synthase ABC2_membrane PF01061.24 KKK23290.1 - 1.9e-89 298.7 64.0 1.5e-46 158.5 22.5 3.2 4 0 0 4 4 4 2 ABC-2 type transporter PDR_CDR PF06422.12 KKK23290.1 - 1.6e-37 127.2 6.7 6.5e-31 106.1 0.0 3.4 3 0 0 3 3 3 2 CDR ABC transporter ABC_tran PF00005.27 KKK23290.1 - 9.3e-36 123.4 0.0 1.8e-16 60.9 0.0 3.7 4 0 0 4 4 4 2 ABC transporter ABC_trans_N PF14510.6 KKK23290.1 - 6e-20 71.6 0.5 1.7e-19 70.2 0.1 2.0 2 0 0 2 2 2 1 ABC-transporter N-terminal ABC2_membrane_3 PF12698.7 KKK23290.1 - 3.3e-05 23.2 12.7 3.3e-05 23.2 12.7 3.0 2 1 0 2 2 2 1 ABC-2 family transporter protein RsgA_GTPase PF03193.16 KKK23290.1 - 0.00027 20.9 0.0 0.013 15.4 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 KKK23290.1 - 0.00035 21.0 0.0 0.19 12.1 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.6 KKK23290.1 - 0.00062 19.4 0.1 0.0018 17.9 0.0 1.7 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 KKK23290.1 - 0.0088 15.5 0.0 0.67 9.3 0.0 2.8 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KKK23290.1 - 0.013 15.2 0.1 0.88 9.4 0.1 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_33 PF13671.6 KKK23290.1 - 0.022 14.9 0.0 2.1 8.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KKK23290.1 - 0.023 15.3 0.0 0.22 12.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.6 KKK23290.1 - 0.023 14.5 0.1 4.5 7.0 0.1 2.6 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system NACHT PF05729.12 KKK23290.1 - 0.14 12.1 3.1 14 5.6 0.1 3.3 3 0 0 3 3 3 0 NACHT domain AAA_30 PF13604.6 KKK23290.1 - 0.18 11.5 0.2 7.5 6.2 0.1 2.3 2 0 0 2 2 2 0 AAA domain zf-Sec23_Sec24 PF04810.15 KKK23290.1 - 0.18 11.9 0.1 0.68 10.0 0.0 2.1 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger AAA_22 PF13401.6 KKK23290.1 - 0.29 11.4 0.7 12 6.2 0.1 2.6 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 KKK23290.1 - 0.29 10.7 1.1 1.3 8.6 0.1 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Acetyltransf_1 PF00583.25 KKK23292.1 - 0.0034 17.6 0.0 0.0079 16.4 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KKK23292.1 - 0.051 13.5 0.0 0.12 12.3 0.0 1.6 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KKK23292.1 - 0.12 12.8 0.0 13 6.3 0.0 2.2 1 1 0 2 2 2 0 Acetyltransferase (GNAT) domain Phage_holin_5_1 PF06946.11 KKK23297.1 - 1.3 9.5 10.1 0.16 12.4 0.4 2.8 3 0 0 3 3 3 0 Bacteriophage A118-like holin, Hol118 Bestrophin PF01062.21 KKK23298.1 - 6.7e-39 134.0 0.0 1.1e-38 133.3 0.0 1.2 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel T6SS_VasE PF05936.12 KKK23298.1 - 0.064 12.0 0.0 0.095 11.4 0.0 1.2 1 0 0 1 1 1 0 Bacterial Type VI secretion, VC_A0110, EvfL, ImpJ, VasE AadA_C PF18280.1 KKK23300.1 - 0.18 11.9 0.2 33 4.7 0.0 2.5 2 0 0 2 2 2 0 Aminoglycoside adenyltransferase C-terminal domain DUF167 PF02594.16 KKK23301.1 - 1.6e-13 50.5 0.5 1.9e-07 31.1 0.0 2.2 2 0 0 2 2 2 2 Uncharacterised ACR, YggU family COG1872 DUF3638 PF12340.8 KKK23305.1 - 1.6e-89 299.1 1.8 1.6e-89 299.1 1.8 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3638) MFS_1 PF07690.16 KKK23306.1 - 3.5e-33 115.0 26.3 3.5e-33 115.0 26.3 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 KKK23306.1 - 0.00032 20.1 0.7 0.00032 20.1 0.7 1.7 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB LapA_dom PF06305.11 KKK23306.1 - 0.58 10.0 2.1 1.1 9.1 0.0 2.6 2 1 0 2 2 2 0 Lipopolysaccharide assembly protein A domain CLTH PF10607.9 KKK23313.1 - 3.3e-33 114.6 0.0 5.1e-33 114.0 0.0 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain SPRY PF00622.28 KKK23313.1 - 3.2e-19 69.2 0.3 6.2e-19 68.3 0.3 1.5 1 0 0 1 1 1 1 SPRY domain LisH PF08513.11 KKK23313.1 - 0.00021 21.2 0.6 0.00052 19.9 0.1 2.0 2 0 0 2 2 2 1 LisH OpuAC PF04069.12 KKK23313.1 - 0.03 13.9 0.7 1.8 8.1 0.4 2.3 1 1 1 2 2 2 0 Substrate binding domain of ABC-type glycine betaine transport system E1_DerP2_DerF2 PF02221.15 KKK23323.1 - 1.9e-31 109.2 0.1 2.5e-31 108.9 0.1 1.1 1 0 0 1 1 1 1 ML domain Big_9 PF17963.1 KKK23323.1 - 9.3e-05 23.1 0.0 0.00016 22.4 0.0 1.4 1 0 0 1 1 1 1 Bacterial Ig domain Cadherin_4 PF17803.1 KKK23323.1 - 0.0018 18.9 0.1 0.003 18.2 0.1 1.4 1 0 0 1 1 1 1 Bacterial cadherin-like domain Alph_Pro_TM PF09608.10 KKK23323.1 - 0.11 12.3 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Putative transmembrane protein (Alph_Pro_TM) NPCBM_assoc PF10633.9 KKK23323.1 - 0.13 12.6 0.1 2.5 8.4 0.0 2.4 2 0 0 2 2 2 0 NPCBM-associated, NEW3 domain of alpha-galactosidase Med10 PF09748.9 KKK23336.1 - 1.1e-43 148.1 0.0 1.2e-43 147.9 0.0 1.0 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex DUF3877 PF12993.7 KKK23336.1 - 0.044 13.6 0.0 0.048 13.5 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function, E. rectale Gene description (DUF3877) Pkinase PF00069.25 KKK23337.1 - 5.8e-40 137.3 0.0 8.4e-40 136.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK23337.1 - 7.3e-28 97.5 0.0 1.1e-27 97.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KKK23337.1 - 0.045 13.1 0.0 0.077 12.3 0.0 1.3 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 KKK23337.1 - 0.076 12.9 0.1 7.1 6.5 0.0 2.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family Spt5_N PF11942.8 KKK23337.1 - 0.35 11.9 3.9 1.6 9.8 0.3 2.7 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Utp14 PF04615.13 KKK23338.1 - 0.39 9.2 62.5 0.53 8.8 62.5 1.1 1 0 0 1 1 1 0 Utp14 protein Amidase PF01425.21 KKK23339.1 - 5.3e-85 286.1 0.0 8.1e-85 285.5 0.0 1.3 1 0 0 1 1 1 1 Amidase AT_hook PF02178.19 KKK23340.1 - 0.087 12.7 21.5 0.87 9.7 5.8 3.1 2 0 0 2 2 2 0 AT hook motif XPG_I PF00867.18 KKK23341.1 - 5.4e-24 84.4 0.0 1.4e-23 83.0 0.0 1.8 1 0 0 1 1 1 1 XPG I-region GEN1_C PF18380.1 KKK23341.1 - 4.3e-23 82.2 0.0 4.3e-23 82.2 0.0 2.6 2 1 1 3 3 3 1 Holliday junction resolvase Gen1 C-terminal domain XPG_I_2 PF12813.7 KKK23341.1 - 0.11 11.9 0.0 0.25 10.8 0.0 1.5 1 0 0 1 1 1 0 XPG domain containing Mu-transpos_C PF09299.11 KKK23341.1 - 0.14 12.2 0.0 0.3 11.1 0.0 1.5 1 0 0 1 1 1 0 Mu transposase, C-terminal Gag_p12 PF01141.18 KKK23341.1 - 6.1 7.2 9.3 1 9.7 0.3 3.2 3 0 0 3 3 3 0 Gag polyprotein, inner coat protein p12 adh_short_C2 PF13561.6 KKK23342.1 - 3.5e-47 160.9 0.0 5.1e-47 160.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KKK23342.1 - 1.4e-39 135.5 0.0 2e-39 135.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KKK23342.1 - 7.5e-06 26.0 0.0 2.7e-05 24.2 0.0 2.0 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KKK23342.1 - 1.4e-05 24.7 0.0 1.8e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 KKK23342.1 - 0.062 12.7 0.0 0.079 12.3 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) p450 PF00067.22 KKK23343.1 - 6.1e-39 134.0 0.0 8.4e-39 133.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Aldose_epim PF01263.20 KKK23345.1 - 8.9e-50 169.7 0.0 1.2e-49 169.2 0.0 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase Fer2_4 PF13510.6 KKK23345.1 - 0.0069 16.4 0.0 0.91 9.6 0.0 2.4 2 0 0 2 2 2 2 2Fe-2S iron-sulfur cluster binding domain FXMR_C2 PF16098.5 KKK23345.1 - 0.08 13.4 0.0 0.13 12.7 0.0 1.3 1 0 0 1 1 1 0 Fragile X-related mental retardation protein C-terminal region 2 Cpn60_TCP1 PF00118.24 KKK23346.1 - 1.1e-165 552.0 0.2 1.2e-165 551.9 0.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family His_Phos_1 PF00300.22 KKK23346.1 - 0.11 12.2 0.0 9.5 5.9 0.0 2.3 2 0 0 2 2 2 0 Histidine phosphatase superfamily (branch 1) CFEM PF05730.11 KKK23347.1 - 0.00015 21.8 5.1 0.00015 21.8 5.1 3.3 3 0 0 3 3 3 1 CFEM domain Tme5_EGF_like PF09064.10 KKK23347.1 - 0.025 14.4 1.9 0.099 12.6 1.9 2.0 1 0 0 1 1 1 0 Thrombomodulin like fifth domain, EGF-like MFS_1 PF07690.16 KKK23348.1 - 8.3e-23 80.9 56.4 2.3e-21 76.1 56.4 2.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KKK23348.1 - 2.6e-10 39.8 13.5 2.6e-10 39.8 13.5 3.1 4 0 0 4 4 4 1 Sugar (and other) transporter OATP PF03137.20 KKK23348.1 - 0.36 9.1 8.1 0.019 13.3 2.0 1.9 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family CRF1 PF10380.9 KKK23349.1 - 0.0095 16.3 1.5 0.022 15.1 0.0 2.4 2 0 0 2 2 2 1 Transcription factor CRF1 DUF2752 PF10825.8 KKK23351.1 - 0.00035 20.6 1.2 0.00059 19.8 1.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2752) DUF2852 PF11014.8 KKK23351.1 - 0.0065 16.6 4.4 0.9 9.7 0.5 2.7 2 1 0 2 2 2 2 Protein of unknown function (DUF2852) MLANA PF14991.6 KKK23351.1 - 0.052 13.8 2.6 6.4 7.1 0.1 2.9 2 1 0 2 2 2 0 Protein melan-A Phage_holin_2_4 PF16082.5 KKK23351.1 - 1.8 8.3 4.3 3.3 7.5 1.4 2.8 1 1 1 2 2 2 0 Bacteriophage holin family, superfamily II-like Zn_clus PF00172.18 KKK23352.1 - 2.1e-06 27.7 9.9 2.1e-06 27.7 9.9 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KKK23352.1 - 0.0043 16.1 0.2 0.012 14.7 0.2 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain HSBP1 PF06825.12 KKK23352.1 - 0.29 11.0 2.8 0.29 11.0 1.2 1.8 2 0 0 2 2 2 0 Heat shock factor binding protein 1 ADH_zinc_N PF00107.26 KKK23353.1 - 3.5e-18 65.8 0.0 5.3e-18 65.2 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KKK23353.1 - 1.7e-10 42.0 0.0 3.1e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 KKK23353.1 - 5.1e-07 29.6 0.0 5.7e-06 26.2 0.0 2.3 1 1 0 1 1 1 1 N-terminal domain of oxidoreductase Actin PF00022.19 KKK23354.1 - 1.5e-20 73.2 0.0 4.3e-14 51.9 0.0 3.1 3 0 0 3 3 3 3 Actin DUF1168 PF06658.12 KKK23355.1 - 3.8e-39 133.6 11.5 5.4e-39 133.1 11.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) Lyase_catalyt PF09093.11 KKK23355.1 - 0.059 12.5 0.0 0.084 12.0 0.0 1.1 1 0 0 1 1 1 0 Lyase, catalytic PPL5 PF18168.1 KKK23355.1 - 0.3 10.4 3.2 0.38 10.0 3.2 1.1 1 0 0 1 1 1 0 Prim-pol family 5 RR_TM4-6 PF06459.12 KKK23355.1 - 1.1 9.1 5.5 1.5 8.6 5.5 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CDC45 PF02724.14 KKK23355.1 - 7.6 4.7 10.8 9.3 4.4 10.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Peptidase_S49_N PF08496.10 KKK23355.1 - 7.8 6.6 5.9 11 6.1 5.9 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal ADH_zinc_N PF00107.26 KKK23356.1 - 3.7e-10 39.9 0.3 4.5e-09 36.4 0.3 2.4 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KKK23356.1 - 6.5e-06 26.0 0.0 2.5e-05 24.1 0.0 2.1 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain UQ_con PF00179.26 KKK23357.1 - 9.5e-23 80.4 0.0 1.6e-22 79.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme SH3_15 PF18346.1 KKK23357.1 - 0.015 15.6 0.0 17 5.8 0.0 3.5 4 0 0 4 4 4 0 Mind bomb SH3 repeat domain FAM104 PF15434.6 KKK23357.1 - 0.65 10.6 2.5 7.7 7.1 0.2 2.4 2 0 0 2 2 2 0 Family 104 Cupin_2 PF07883.11 KKK23358.1 - 0.00097 18.8 0.3 0.071 12.8 0.1 2.2 2 0 0 2 2 2 2 Cupin domain MannoseP_isomer PF01050.18 KKK23358.1 - 0.078 12.9 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Mannose-6-phosphate isomerase FMO-like PF00743.19 KKK23359.1 - 5.2e-10 38.4 0.0 6e-09 34.9 0.0 2.3 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 KKK23359.1 - 2.7e-07 30.7 0.0 7.3e-07 29.3 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KKK23359.1 - 2.7e-06 26.9 0.0 2.4e-05 23.8 0.0 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KKK23359.1 - 0.00033 20.7 0.0 0.0014 18.6 0.0 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 KKK23359.1 - 0.018 14.3 0.0 4.7 6.3 0.0 2.6 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KKK23359.1 - 0.022 13.9 0.0 0.081 12.0 0.0 1.9 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) 2-Hacid_dh_C PF02826.19 KKK23359.1 - 0.17 11.3 0.0 0.31 10.4 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain zf-PARP PF00645.18 KKK23360.1 - 8.6e-24 84.2 0.1 2.5e-23 82.7 0.1 1.8 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region MCM PF00493.23 KKK23360.1 - 0.1 11.7 0.1 0.15 11.1 0.1 1.2 1 0 0 1 1 1 0 MCM P-loop domain NmrA PF05368.13 KKK23361.1 - 2.3e-22 79.7 0.0 2.9e-22 79.4 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KKK23361.1 - 2.5e-12 47.1 0.0 4.2e-12 46.3 0.0 1.5 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KKK23361.1 - 7.2e-09 35.5 0.8 5e-08 32.7 0.6 2.2 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KKK23361.1 - 5.5e-06 26.4 0.6 2.1e-05 24.5 0.4 1.8 2 0 0 2 2 2 1 KR domain Sacchrp_dh_NADP PF03435.18 KKK23361.1 - 7.5e-05 23.0 0.1 0.00016 21.9 0.1 1.5 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain LpxI_N PF17930.1 KKK23361.1 - 0.0014 18.5 0.1 0.0025 17.7 0.1 1.3 1 0 0 1 1 1 1 LpxI N-terminal domain GDP_Man_Dehyd PF16363.5 KKK23361.1 - 0.0032 16.9 0.6 0.0059 16.0 0.6 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KKK23361.1 - 0.037 13.0 0.0 0.053 12.5 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 KKK23361.1 - 0.039 13.4 0.3 0.065 12.7 0.3 1.4 1 0 0 1 1 1 0 short chain dehydrogenase NAD_binding_4 PF07993.12 KKK23361.1 - 0.05 12.8 0.0 0.07 12.3 0.0 1.2 1 0 0 1 1 1 0 Male sterility protein CbiJ PF02571.14 KKK23361.1 - 0.15 11.5 0.2 0.24 10.8 0.2 1.2 1 0 0 1 1 1 0 Precorrin-6x reductase CbiJ/CobK AA_permease_2 PF13520.6 KKK23362.1 - 3.9e-32 111.6 49.9 5e-32 111.3 49.9 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KKK23362.1 - 2.8e-09 36.1 36.3 3.9e-09 35.6 36.3 1.2 1 0 0 1 1 1 1 Amino acid permease Abhydrolase_3 PF07859.13 KKK23363.1 - 1e-49 169.3 0.0 1.3e-49 168.9 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KKK23363.1 - 4.2e-07 29.2 0.0 1.3e-06 27.6 0.0 1.6 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_6 PF12697.7 KKK23363.1 - 0.004 17.8 0.5 0.0071 17.0 0.5 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Say1_Mug180 PF10340.9 KKK23363.1 - 0.13 11.1 0.0 0.24 10.2 0.0 1.3 1 1 0 1 1 1 0 Steryl acetyl hydrolase Esterase_phd PF10503.9 KKK23363.1 - 0.14 11.7 0.2 7 6.1 0.0 2.2 2 0 0 2 2 2 0 Esterase PHB depolymerase COesterase PF00135.28 KKK23364.1 - 2e-54 185.3 0.0 2.6e-54 185.0 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KKK23364.1 - 1.9e-10 41.0 0.2 5.4e-10 39.5 0.2 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 KKK23364.1 - 0.024 14.3 0.0 0.17 11.5 0.0 2.0 1 1 0 1 1 1 0 Putative esterase SSF PF00474.17 KKK23367.1 - 6.1e-17 61.6 31.9 1.1e-16 60.7 31.9 1.5 1 0 0 1 1 1 1 Sodium:solute symporter family Dynein_light PF01221.18 KKK23368.1 - 7.2e-37 125.6 5.3 1.4e-36 124.6 5.3 1.4 1 1 0 1 1 1 1 Dynein light chain type 1 DUF4723 PF15851.5 KKK23368.1 - 0.0053 16.9 0.0 0.0076 16.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4723) SYCP2_SLD PF18584.1 KKK23368.1 - 0.024 14.9 0.3 0.035 14.3 0.3 1.3 1 0 0 1 1 1 0 Synaptonemal complex 2 Spt16M-like domain Phage_B PF02304.15 KKK23368.1 - 0.039 14.3 0.1 0.047 14.1 0.1 1.2 1 0 0 1 1 1 0 Scaffold protein B RhoGEF67_u1 PF16615.5 KKK23368.1 - 0.059 13.9 0.1 0.099 13.2 0.1 1.3 1 0 0 1 1 1 0 Unstructured region one on RhoGEF 6 and 7 RRM_1 PF00076.22 KKK23369.1 - 1.2e-74 246.0 1.0 1.5e-19 69.6 0.0 5.5 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KKK23369.1 - 4.6e-08 32.7 0.0 0.015 14.9 0.0 4.0 4 1 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KKK23369.1 - 7.2e-07 29.1 0.0 0.61 10.1 0.0 4.5 5 0 0 5 5 5 3 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 KKK23369.1 - 0.00016 21.7 0.1 5.7 7.1 0.0 3.9 3 0 0 3 3 3 2 RNA recognition motif RRM_occluded PF16842.5 KKK23369.1 - 0.00048 19.9 0.0 1.4 8.8 0.0 4.0 4 0 0 4 4 4 2 Occluded RNA-recognition motif Limkain-b1 PF11608.8 KKK23369.1 - 0.014 15.4 0.1 35 4.6 0.0 4.6 5 0 0 5 5 5 0 Limkain b1 TEA PF01285.18 KKK23370.1 - 3.1e-28 97.6 0.0 7.5e-28 96.4 0.0 1.7 1 0 0 1 1 1 1 TEA/ATTS domain Aldo_ket_red PF00248.21 KKK23371.1 - 4.7e-40 137.6 0.0 6e-40 137.3 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family DUF1330 PF07045.11 KKK23372.1 - 0.092 13.1 0.2 0.19 12.1 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1330) LRR_4 PF12799.7 KKK23374.1 - 3.3e-21 75.0 12.8 1.3e-09 38.1 0.9 3.1 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KKK23374.1 - 9.7e-10 38.1 15.8 5.6e-05 22.8 4.8 2.8 2 1 0 3 3 3 2 Leucine rich repeat LRR_9 PF14580.6 KKK23374.1 - 2.7e-07 30.3 1.7 0.0031 17.0 0.1 2.2 1 1 1 2 2 2 2 Leucine-rich repeat LRR_6 PF13516.6 KKK23374.1 - 2.6e-06 27.1 12.1 0.046 13.8 0.2 5.1 5 0 0 5 5 5 2 Leucine Rich repeat LRR_1 PF00560.33 KKK23374.1 - 7.2e-06 25.8 9.6 5 8.1 0.0 5.3 4 1 0 4 4 4 2 Leucine Rich Repeat DUF1473 PF07341.11 KKK23374.1 - 0.027 14.2 0.6 0.2 11.4 0.2 1.9 1 1 0 2 2 2 0 Protein of unknown function (DUF1473) E1-E2_ATPase PF00122.20 KKK23376.1 - 3.1e-52 176.7 9.3 6.3e-52 175.7 2.5 3.0 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 KKK23376.1 - 5.6e-47 159.8 6.6 5.6e-47 159.8 6.6 1.8 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KKK23376.1 - 2.1e-21 77.2 0.8 3e-20 73.4 0.8 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KKK23376.1 - 7.3e-19 67.7 0.0 1.4e-18 66.8 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KKK23376.1 - 2.6e-16 59.0 0.0 8.3e-16 57.4 0.0 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KKK23376.1 - 1.3e-07 31.7 1.8 7.2e-06 25.9 0.8 2.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KKK23376.1 - 8.5e-06 26.3 0.0 3.6e-05 24.2 0.0 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase eIF3_subunit PF08597.10 KKK23378.1 - 2.6e-69 233.8 33.5 2.9e-69 233.7 33.5 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit PNISR PF15996.5 KKK23378.1 - 0.0077 16.5 9.6 0.0077 16.5 9.6 2.2 2 0 0 2 2 2 1 Arginine/serine-rich protein PNISR DUF2967 PF11179.8 KKK23378.1 - 0.073 11.2 8.1 0.12 10.5 8.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) PRP4 PF08799.11 KKK23378.1 - 0.58 9.8 2.5 1.4 8.6 2.5 1.6 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like FAM60A PF15396.6 KKK23378.1 - 9.5 6.2 12.7 5.4 6.9 7.1 2.1 2 0 0 2 2 2 0 Protein Family FAM60A 14-3-3 PF00244.20 KKK23379.1 - 1.1e-107 358.6 2.3 1.3e-107 358.3 2.3 1.1 1 0 0 1 1 1 1 14-3-3 protein Orbi_VP5 PF00901.17 KKK23379.1 - 0.02 13.3 1.1 0.032 12.6 1.1 1.3 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 Sec39 PF08314.11 KKK23388.1 - 1.4e-262 873.5 0.0 1.6e-262 873.3 0.0 1.0 1 0 0 1 1 1 1 Secretory pathway protein Sec39 Ndufs5 PF10200.9 KKK23389.1 - 0.00083 19.6 0.1 0.0011 19.2 0.1 1.2 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa UPF0203 PF05254.12 KKK23389.1 - 0.0021 18.3 0.6 0.0032 17.7 0.6 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) DUF3128 PF11326.8 KKK23389.1 - 0.016 15.5 2.5 0.081 13.3 2.5 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3128) COX6B PF02297.17 KKK23389.1 - 0.021 15.0 0.2 0.036 14.3 0.2 1.4 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIb NYD-SP28_assoc PF14775.6 KKK23389.1 - 0.068 13.3 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 Sperm tail C-terminal domain UPF0449 PF15136.6 KKK23407.1 - 0.0077 16.7 0.7 0.0077 16.7 0.7 1.9 2 0 0 2 2 2 1 Uncharacterised protein family UPF0449 CCDC106 PF15794.5 KKK23407.1 - 0.023 14.4 0.3 0.023 14.4 0.3 2.9 3 1 1 4 4 4 0 Coiled-coil domain-containing protein 106 Phage_Mu_Gam PF07352.12 KKK23407.1 - 0.028 14.3 0.5 0.043 13.7 0.5 1.2 1 0 0 1 1 1 0 Bacteriophage Mu Gam like protein DUF4337 PF14235.6 KKK23407.1 - 5.4 7.1 5.8 8.5 6.5 5.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) bZIP_2 PF07716.15 KKK23407.1 - 7.3 6.8 15.4 11 6.2 14.2 1.8 1 1 1 2 2 2 0 Basic region leucine zipper His_Phos_2 PF00328.22 KKK23408.1 - 9.2e-76 255.7 0.0 1e-75 255.5 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Ribosomal_60s PF00428.19 KKK23409.1 - 0.11 13.1 0.3 0.11 13.1 0.3 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein CUE PF02845.16 KKK23410.1 - 3.1e-12 45.9 0.0 5.3e-12 45.2 0.0 1.4 1 0 0 1 1 1 1 CUE domain BTB_2 PF02214.22 KKK23412.1 - 3.2e-08 33.8 0.2 0.00069 19.9 0.0 2.5 2 0 0 2 2 2 2 BTB/POZ domain APC_basic PF05956.11 KKK23412.1 - 0.0083 15.6 2.3 0.012 15.1 2.3 1.2 1 0 0 1 1 1 1 APC basic domain GMC_oxred_N PF00732.19 KKK23413.1 - 7.4e-36 124.0 1.1 2.7e-35 122.2 0.3 2.1 2 1 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KKK23413.1 - 1.4e-31 110.0 0.1 9.2e-30 104.1 0.0 2.4 2 0 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KKK23413.1 - 1.7e-07 30.7 0.4 5.1e-06 25.8 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 KKK23413.1 - 9.3e-05 21.8 0.2 0.0002 20.7 0.1 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KKK23413.1 - 0.00021 21.4 0.0 0.0027 17.9 0.0 2.7 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KKK23413.1 - 0.00054 19.3 0.1 0.0024 17.1 0.0 1.9 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.19 KKK23413.1 - 0.0013 18.0 0.0 0.0022 17.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KKK23413.1 - 0.0035 16.1 0.1 0.009 14.8 0.1 1.7 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.7 KKK23413.1 - 0.012 14.9 0.6 0.02 14.3 0.6 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase DAO PF01266.24 KKK23413.1 - 0.016 14.8 4.7 0.86 9.1 4.7 2.5 1 1 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.22 KKK23413.1 - 0.031 13.4 0.1 0.072 12.2 0.0 1.6 2 0 0 2 2 2 0 Glucose inhibited division protein A IlvN PF07991.12 KKK23413.1 - 0.068 12.7 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Pyr_redox PF00070.27 KKK23413.1 - 0.15 12.7 0.0 0.36 11.4 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase F-box-like PF12937.7 KKK23414.1 - 0.0047 16.8 1.5 0.0047 16.8 1.5 1.7 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KKK23414.1 - 0.021 14.7 0.7 0.053 13.4 0.7 1.6 1 0 0 1 1 1 0 F-box domain AMP-binding PF00501.28 KKK23415.1 - 4.7e-104 348.3 0.0 6.2e-104 347.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KKK23415.1 - 1.9e-11 44.8 0.0 3.9e-11 43.8 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Methyltr_RsmB-F PF01189.17 KKK23416.1 - 7.7e-16 58.3 0.0 1e-06 28.5 0.0 3.3 2 1 0 2 2 2 2 16S rRNA methyltransferase RsmB/F Acetyltransf_7 PF13508.7 KKK23417.1 - 2.2e-09 37.6 0.0 4.4e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KKK23417.1 - 1.4e-07 31.5 0.0 0.015 15.2 0.0 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KKK23417.1 - 1e-05 25.7 0.2 8.6e-05 22.8 0.1 2.1 2 1 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_5 PF13444.6 KKK23417.1 - 2.8e-05 24.7 0.0 0.00025 21.7 0.0 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KKK23417.1 - 0.00075 19.6 0.0 0.0013 18.8 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 KKK23417.1 - 0.0036 17.4 0.1 0.017 15.2 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KKK23417.1 - 0.07 13.1 0.0 11 6.1 0.0 2.4 2 0 0 2 2 2 0 FR47-like protein WD40 PF00400.32 KKK23427.1 - 1.9e-25 88.6 23.8 2.7e-05 24.9 0.5 7.0 6 2 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKK23427.1 - 8.7e-12 45.2 7.7 0.00065 19.9 0.4 4.5 3 2 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain TFIIIC_delta PF12657.7 KKK23427.1 - 1.1e-05 25.4 10.1 0.017 15.1 0.1 3.1 1 1 2 3 3 3 3 Transcription factor IIIC subunit delta N-term Sugar_tr PF00083.24 KKK23428.1 - 8.3e-61 206.2 18.3 1.3e-29 103.4 5.7 4.1 2 1 2 4 4 4 4 Sugar (and other) transporter MFS_1 PF07690.16 KKK23428.1 - 9.4e-10 37.9 34.6 0.001 18.1 8.6 3.2 2 1 1 3 3 3 3 Major Facilitator Superfamily Pkinase PF00069.25 KKK23429.1 - 1.9e-17 63.5 0.0 6e-17 61.9 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK23429.1 - 8.2e-08 31.8 0.0 5.2e-07 29.2 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase DUF3433 PF11915.8 KKK23429.1 - 0.051 14.0 0.0 0.19 12.2 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3433) Peptidase_M49 PF03571.15 KKK23430.1 - 4.6e-243 807.6 0.0 6.1e-243 807.2 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M49 SNF5 PF04855.12 KKK23431.1 - 6.3e-88 294.6 0.0 7.9e-88 294.2 0.0 1.1 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 GATA PF00320.27 KKK23431.1 - 0.00011 21.7 0.9 0.00035 20.1 0.9 1.9 1 0 0 1 1 1 1 GATA zinc finger Rubredoxin_2 PF18073.1 KKK23431.1 - 2 8.2 5.3 1.8 8.4 1.7 2.2 2 0 0 2 2 2 0 Rubredoxin metal binding domain Peptidase_M91 PF14891.6 KKK23432.1 - 0.0045 17.3 2.8 0.0085 16.4 2.8 1.4 1 0 0 1 1 1 1 Effector protein Aminotran_4 PF01063.19 KKK23433.1 - 1.9e-35 122.8 0.0 2.6e-35 122.3 0.0 1.2 1 0 0 1 1 1 1 Amino-transferase class IV ABC_tran PF00005.27 KKK23435.1 - 3.8e-48 163.5 0.6 4.2e-23 82.4 0.0 3.2 3 0 0 3 3 3 2 ABC transporter ABC_tran_Xtn PF12848.7 KKK23435.1 - 9e-21 73.7 7.9 9e-21 73.7 7.9 3.8 5 0 0 5 5 3 1 ABC transporter AAA_21 PF13304.6 KKK23435.1 - 4.1e-15 56.4 2.2 0.0042 16.9 0.0 4.6 4 1 0 5 5 5 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KKK23435.1 - 9.5e-11 41.5 1.0 0.024 14.1 0.0 4.6 4 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KKK23435.1 - 2e-07 31.7 12.6 0.015 15.8 0.0 5.0 5 0 0 5 5 5 2 AAA domain MMR_HSR1 PF01926.23 KKK23435.1 - 2.4e-06 27.6 0.0 0.037 14.1 0.0 3.1 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_22 PF13401.6 KKK23435.1 - 3.3e-06 27.4 0.0 0.023 15.0 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 KKK23435.1 - 4.3e-06 27.3 0.3 0.3 11.6 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_30 PF13604.6 KKK23435.1 - 5.6e-06 26.2 0.3 0.0054 16.5 0.0 3.3 2 1 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 KKK23435.1 - 5.8e-06 26.3 0.6 0.028 14.3 0.0 2.9 2 1 1 3 3 3 2 RsgA GTPase AAA_29 PF13555.6 KKK23435.1 - 1.3e-05 24.9 0.1 0.15 11.8 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 KKK23435.1 - 1.9e-05 25.1 3.5 0.18 12.2 2.2 3.0 2 1 0 2 2 2 2 AAA ATPase domain AAA_33 PF13671.6 KKK23435.1 - 5e-05 23.5 0.3 0.43 10.7 0.0 3.2 2 1 0 2 2 2 2 AAA domain AAA_24 PF13479.6 KKK23435.1 - 0.00022 21.0 0.3 0.85 9.3 0.1 2.9 3 0 0 3 3 2 2 AAA domain AAA_28 PF13521.6 KKK23435.1 - 0.00038 20.7 4.0 0.13 12.5 0.0 3.1 3 0 0 3 3 2 2 AAA domain Dynamin_N PF00350.23 KKK23435.1 - 0.00047 20.2 1.9 0.83 9.7 0.0 4.0 4 0 0 4 4 4 1 Dynamin family AAA_15 PF13175.6 KKK23435.1 - 0.0017 18.1 14.0 0.23 11.1 0.0 4.6 4 1 0 5 5 5 2 AAA ATPase domain AAA PF00004.29 KKK23435.1 - 0.0024 18.3 0.1 2 8.8 0.1 2.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 KKK23435.1 - 0.0034 17.3 0.1 0.88 9.5 0.0 2.6 2 0 0 2 2 2 1 NACHT domain AAA_14 PF13173.6 KKK23435.1 - 0.0091 16.0 0.0 7 6.7 0.0 3.2 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KKK23435.1 - 0.011 16.1 0.0 6.5 7.2 0.0 2.7 2 0 0 2 2 2 0 RNA helicase MeaB PF03308.16 KKK23435.1 - 0.017 14.1 2.4 2.3 7.1 0.0 2.7 3 0 0 3 3 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Rad17 PF03215.15 KKK23435.1 - 0.018 15.0 0.2 1.3 8.9 0.0 3.0 2 1 1 3 3 3 0 Rad17 P-loop domain Zeta_toxin PF06414.12 KKK23435.1 - 0.019 14.2 1.6 5.5 6.2 0.1 3.2 3 0 0 3 3 3 0 Zeta toxin ATP-synt_ab PF00006.25 KKK23435.1 - 0.021 14.5 0.0 0.43 10.2 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Roc PF08477.13 KKK23435.1 - 0.034 14.4 0.1 7.5 6.8 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase NTPase_1 PF03266.15 KKK23435.1 - 0.047 13.6 0.0 4.2 7.3 0.0 2.7 2 0 0 2 2 2 0 NTPase NB-ARC PF00931.22 KKK23435.1 - 0.067 12.4 0.0 13 4.9 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain AAA_5 PF07728.14 KKK23435.1 - 0.068 13.2 0.3 10 6.1 0.0 2.8 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 KKK23435.1 - 0.069 12.7 0.0 7.5 6.0 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region TsaE PF02367.17 KKK23435.1 - 0.096 12.7 0.0 13 5.8 0.0 2.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE cobW PF02492.19 KKK23435.1 - 0.1 12.2 3.2 2.2 7.8 0.5 2.9 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_27 PF13514.6 KKK23435.1 - 0.1 12.2 5.8 4.3 6.9 0.0 3.7 5 0 0 5 5 2 0 AAA domain PduV-EutP PF10662.9 KKK23435.1 - 0.15 11.8 0.0 23 4.7 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation PRK PF00485.18 KKK23435.1 - 0.57 9.9 3.0 2.2 8.0 0.0 3.1 3 1 1 4 4 4 0 Phosphoribulokinase / Uridine kinase family DUF87 PF01935.17 KKK23435.1 - 0.78 9.8 8.1 11 6.1 0.0 4.1 5 0 0 5 5 4 0 Helicase HerA, central domain Ribosomal_L22 PF00237.19 KKK23445.1 - 3.3e-31 107.6 1.1 5.4e-31 106.9 0.1 1.9 2 0 0 2 2 2 1 Ribosomal protein L22p/L17e His_Phos_1 PF00300.22 KKK23446.1 - 2e-10 40.7 0.1 6.1e-10 39.1 0.1 1.8 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) NifU_N PF01592.16 KKK23447.1 - 2.2e-50 170.1 0.0 2.8e-50 169.8 0.0 1.1 1 0 0 1 1 1 1 NifU-like N terminal domain Spermine_synth PF01564.17 KKK23449.1 - 4.4e-07 29.5 0.0 7.2e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Methyltransf_30 PF05430.11 KKK23449.1 - 0.018 14.9 0.0 0.035 14.0 0.0 1.4 1 0 0 1 1 1 0 S-adenosyl-L-methionine-dependent methyltransferase DLIC PF05783.11 KKK23450.1 - 3.8e-37 128.2 2.2 3e-33 115.4 0.0 3.4 2 2 0 2 2 2 2 Dynein light intermediate chain (DLIC) Urb2 PF10441.9 KKK23450.1 - 0.11 12.4 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Urb2/Npa2 family DUF2052 PF09747.9 KKK23451.1 - 2.2e-22 80.2 17.0 4.6e-12 46.5 0.9 2.2 1 1 1 2 2 2 2 Coiled-coil domain containing protein (DUF2052) AMP-binding PF00501.28 KKK23452.1 - 1.9e-76 257.3 0.0 2.7e-76 256.9 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KKK23452.1 - 6.2e-16 59.1 0.0 1.4e-15 58.0 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain SET PF00856.28 KKK23452.1 - 1.3e-10 42.0 0.1 8.6e-09 36.0 0.1 3.0 2 1 0 2 2 2 1 SET domain DUF2913 PF11140.8 KKK23452.1 - 0.042 13.6 0.0 1.8 8.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2913) IKI3 PF04762.12 KKK23453.1 - 0.093 10.7 0.0 0.11 10.5 0.0 1.0 1 0 0 1 1 1 0 IKI3 family RRM_1 PF00076.22 KKK23454.1 - 4.3e-19 68.1 0.0 9.7e-19 67.0 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KKK23454.1 - 1.2e-05 25.4 0.0 2.8e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif RRM_3 PF08777.11 KKK23454.1 - 0.059 13.4 2.1 0.13 12.3 0.0 2.5 1 1 1 2 2 2 0 RNA binding motif RRM_1 PF00076.22 KKK23455.1 - 8.4e-38 128.0 0.1 3.5e-11 42.8 0.0 4.2 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KKK23455.1 - 6.5e-06 26.0 0.0 0.17 11.9 0.0 2.7 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 KKK23455.1 - 0.024 14.5 0.0 1.5 8.7 0.1 2.5 2 0 0 2 2 2 0 Occluded RNA-recognition motif RRM_3 PF08777.11 KKK23455.1 - 0.055 13.5 0.1 35 4.5 0.0 4.0 4 0 0 4 4 4 0 RNA binding motif Peptidase_S9 PF00326.21 KKK23456.1 - 2.4e-54 184.0 0.1 3.6e-54 183.5 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family PD40 PF07676.12 KKK23456.1 - 0.00022 21.1 0.3 0.23 11.5 0.1 3.0 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat Kri1 PF05178.12 KKK23457.1 - 0.03 14.9 0.5 0.04 14.5 0.5 1.2 1 0 0 1 1 1 0 KRI1-like family Abhydrolase_6 PF12697.7 KKK23459.1 - 3.8e-13 50.6 0.4 5.3e-13 50.1 0.4 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KKK23459.1 - 2.7e-06 26.8 0.0 4.1e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KKK23459.1 - 0.00015 21.6 0.0 0.00019 21.2 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Cauli_DNA-bind PF03310.13 KKK23459.1 - 0.11 12.6 0.3 2.1 8.4 0.0 2.3 2 0 0 2 2 2 0 Caulimovirus DNA-binding protein p450 PF00067.22 KKK23460.1 - 4.2e-65 220.3 0.0 4.9e-65 220.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Gp_dh_C PF02800.20 KKK23461.1 - 1e-20 73.9 0.0 1.2e-20 73.7 0.0 1.1 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Pectinesterase PF01095.19 KKK23462.1 - 5.4e-162 537.5 86.8 1.3e-44 152.2 6.7 7.6 7 1 0 7 7 7 5 Pectinesterase DUF1788 PF08747.11 KKK23462.1 - 0.074 13.1 0.0 0.25 11.3 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1788) FAD_binding_3 PF01494.19 KKK23463.1 - 5.7e-13 48.8 0.4 9.6e-13 48.1 0.4 1.3 1 1 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 KKK23463.1 - 3.3e-05 24.3 0.2 0.00025 21.5 0.2 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KKK23463.1 - 0.00022 21.0 0.4 0.0028 17.3 0.1 2.1 1 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KKK23463.1 - 0.00037 19.8 0.1 0.0053 16.0 0.0 2.0 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase CoA_transf_3 PF02515.17 KKK23463.1 - 0.0011 18.2 0.4 0.002 17.3 0.0 1.6 2 0 0 2 2 2 1 CoA-transferase family III NAD_binding_8 PF13450.6 KKK23463.1 - 0.0013 18.9 0.0 0.0029 17.8 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 KKK23463.1 - 0.011 15.1 0.3 0.02 14.3 0.3 1.6 1 1 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KKK23463.1 - 0.028 13.5 0.0 0.064 12.3 0.0 1.6 1 0 0 1 1 1 0 FAD binding domain AlaDh_PNT_C PF01262.21 KKK23463.1 - 0.03 13.6 0.3 0.047 13.0 0.3 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ApbA PF02558.16 KKK23463.1 - 0.035 13.7 0.1 0.061 13.0 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox_3 PF13738.6 KKK23463.1 - 0.049 12.9 0.0 0.16 11.2 0.1 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KKK23463.1 - 0.074 12.3 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 Thi4 family GIDA PF01134.22 KKK23463.1 - 0.081 12.0 0.2 0.13 11.3 0.2 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A FA_hydroxylase PF04116.13 KKK23464.1 - 2.4e-21 76.4 12.4 2.4e-21 76.4 12.4 2.3 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Fungal_trans PF04082.18 KKK23465.1 - 2.5e-15 56.2 0.4 3.2e-15 55.9 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Sulfatase PF00884.23 KKK23467.1 - 1.2e-21 77.4 0.4 1.8e-21 76.8 0.4 1.2 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 KKK23467.1 - 8.5e-07 28.9 0.0 1.3e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase HSDR_N_2 PF13588.6 KKK23469.1 - 0.0087 16.0 0.0 2.5 8.1 0.0 2.5 2 0 0 2 2 2 2 Type I restriction enzyme R protein N terminus (HSDR_N) Choline_kinase PF01633.20 KKK23469.1 - 0.031 13.9 0.0 1.3 8.5 0.0 2.4 2 0 0 2 2 2 0 Choline/ethanolamine kinase Sporozoite_P67 PF05642.11 KKK23469.1 - 0.075 11.1 0.2 0.1 10.6 0.2 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Glyco_hydro_35 PF01301.19 KKK23469.1 - 0.11 12.1 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolases family 35 MaoC_dehydratas PF01575.19 KKK23470.1 - 3e-26 91.4 0.0 5.9e-26 90.5 0.0 1.4 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 KKK23470.1 - 7.2e-06 26.2 0.0 0.00037 20.6 0.0 2.4 2 1 0 2 2 2 1 N-terminal half of MaoC dehydratase Polyketide_cyc2 PF10604.9 KKK23471.1 - 3.2e-06 27.5 0.0 3.7e-06 27.2 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Aldo_ket_red PF00248.21 KKK23528.1 - 1.8e-52 178.4 0.0 2e-52 178.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Thioredoxin PF00085.20 KKK23529.1 - 1.6e-27 95.5 0.0 1.9e-27 95.3 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KKK23529.1 - 2.2e-07 31.3 0.1 5.9e-07 29.9 0.1 1.6 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KKK23529.1 - 2.5e-07 30.9 0.0 4.8e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 KKK23529.1 - 1.4e-05 25.0 0.0 1.7e-05 24.7 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_9 PF14595.6 KKK23529.1 - 9.2e-05 22.2 0.0 9.9e-05 22.1 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Redoxin PF08534.10 KKK23529.1 - 0.00011 21.9 0.3 0.0016 18.2 0.1 2.0 1 1 1 2 2 2 1 Redoxin OST3_OST6 PF04756.13 KKK23529.1 - 0.00023 20.6 0.0 0.00026 20.4 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family TraF PF13728.6 KKK23529.1 - 0.0021 17.9 0.0 0.0025 17.7 0.0 1.1 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_7 PF13899.6 KKK23529.1 - 0.0061 16.7 0.1 0.014 15.6 0.1 1.6 1 1 0 1 1 1 1 Thioredoxin-like Phosducin PF02114.16 KKK23529.1 - 0.039 12.9 0.0 0.046 12.7 0.0 1.1 1 0 0 1 1 1 0 Phosducin DUF953 PF06110.11 KKK23529.1 - 0.16 11.6 0.1 0.78 9.4 0.1 1.9 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) Thioredoxin_5 PF13743.6 KKK23529.1 - 0.18 11.5 0.0 2.1 8.0 0.0 2.0 1 1 1 2 2 2 0 Thioredoxin Ank_2 PF12796.7 KKK23530.1 - 3.5e-54 181.3 0.0 2e-11 44.3 0.0 6.0 2 2 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KKK23530.1 - 4.3e-50 167.5 0.6 7.5e-09 36.0 0.0 8.2 3 1 6 9 9 9 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 KKK23530.1 - 3.1e-40 131.5 0.5 0.02 15.4 0.0 12.7 13 0 0 13 13 13 9 Ankyrin repeat Aa_trans PF01490.18 KKK23530.1 - 2.5e-39 135.1 31.6 3.5e-39 134.7 31.6 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Ank_5 PF13857.6 KKK23530.1 - 7.2e-37 125.0 0.5 3.2e-06 27.3 0.0 8.4 3 2 4 8 8 8 6 Ankyrin repeats (many copies) Ank PF00023.30 KKK23530.1 - 6e-30 102.4 0.1 0.24 11.9 0.0 12.0 12 0 0 12 12 12 8 Ankyrin repeat F-box-like PF12937.7 KKK23530.1 - 3.3e-06 26.9 0.1 1.2e-05 25.1 0.1 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KKK23530.1 - 0.00015 21.5 0.0 0.00033 20.5 0.0 1.6 1 0 0 1 1 1 1 F-box domain DUF2678 PF10856.8 KKK23530.1 - 0.037 14.0 2.6 0.19 11.6 0.1 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2678) adh_short_C2 PF13561.6 KKK23531.1 - 4.4e-46 157.3 0.2 4.9e-46 157.2 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KKK23531.1 - 2.1e-36 125.2 0.2 2.6e-36 124.9 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KKK23531.1 - 0.0002 21.4 0.1 0.0003 20.8 0.1 1.4 1 1 0 1 1 1 1 KR domain Fungal_trans PF04082.18 KKK23532.1 - 1.7e-08 33.9 0.4 2.6e-08 33.3 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK23532.1 - 7.9e-08 32.3 7.1 1.4e-07 31.5 7.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 KKK23533.1 - 1.2e-35 123.1 66.8 3.8e-25 88.6 33.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Pox_A9 PF04835.12 KKK23533.1 - 1.3 9.3 4.1 0.68 10.1 1.0 2.1 2 0 0 2 2 2 0 A9 protein conserved region MFS_1_like PF12832.7 KKK23533.1 - 8.1 5.2 32.0 2.3 7.0 7.4 3.3 3 1 0 3 3 3 0 MFS_1 like family Pyr_redox_2 PF07992.14 KKK23534.1 - 4.9e-28 98.2 0.0 1.8e-27 96.3 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KKK23534.1 - 1e-07 32.4 0.0 2.1e-05 25.0 0.0 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KKK23534.1 - 0.0062 15.8 0.0 1 8.6 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase SQHop_cyclase_N PF13249.6 KKK23535.1 - 8.1e-90 300.8 0.2 8.3e-83 277.8 0.0 3.4 3 1 0 3 3 3 3 Squalene-hopene cyclase N-terminal domain SQHop_cyclase_C PF13243.6 KKK23535.1 - 4.5e-85 285.6 2.2 5e-81 272.3 0.8 3.4 2 2 0 2 2 2 2 Squalene-hopene cyclase C-terminal domain Prenyltrans PF00432.21 KKK23535.1 - 2.4e-17 62.4 17.4 1.1e-05 25.0 0.1 6.2 6 0 0 6 6 6 4 Prenyltransferase and squalene oxidase repeat TED_complement PF07678.14 KKK23535.1 - 0.00018 20.7 0.3 1.8 7.5 0.0 3.9 4 1 1 5 5 5 2 A-macroglobulin TED domain Pec_lyase PF09492.10 KKK23535.1 - 0.069 12.5 0.0 5.1 6.3 0.0 2.9 2 1 0 2 2 2 0 Pectic acid lyase WD40 PF00400.32 KKK23536.1 - 1.8e-11 44.4 2.2 2.4e-11 44.0 0.5 2.2 2 0 0 2 2 2 1 WD domain, G-beta repeat NACHT PF05729.12 KKK23536.1 - 3.9e-10 39.9 0.1 8.8e-10 38.7 0.1 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KKK23536.1 - 8.5e-10 39.3 0.0 3e-09 37.5 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain NACHT_N PF17100.5 KKK23536.1 - 8.6e-07 29.0 3.8 2.2e-05 24.4 3.8 2.5 1 1 0 1 1 1 1 N-terminal domain of NWD NACHT-NTPase ATPase_2 PF01637.18 KKK23536.1 - 2.9e-06 27.4 0.1 6.7e-05 22.9 0.0 2.2 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_22 PF13401.6 KKK23536.1 - 0.00018 21.8 1.7 0.002 18.4 0.1 3.2 3 1 1 4 4 4 1 AAA domain AAA PF00004.29 KKK23536.1 - 0.00082 19.8 0.0 0.0024 18.3 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 KKK23536.1 - 0.0011 18.3 0.0 0.0026 17.0 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain Ge1_WD40 PF16529.5 KKK23536.1 - 0.0014 17.6 0.0 0.0029 16.6 0.0 1.4 1 0 0 1 1 1 1 WD40 region of Ge1, enhancer of mRNA-decapping protein APS_kinase PF01583.20 KKK23536.1 - 0.0023 17.9 0.1 0.0046 16.9 0.1 1.5 1 0 0 1 1 1 1 Adenylylsulphate kinase ANAPC4_WD40 PF12894.7 KKK23536.1 - 0.014 15.6 0.0 0.033 14.5 0.0 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain AAA_30 PF13604.6 KKK23536.1 - 0.036 13.8 0.0 0.093 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KKK23536.1 - 0.041 14.4 0.3 0.21 12.1 0.1 2.4 2 1 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KKK23536.1 - 0.071 12.4 0.0 0.16 11.3 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin RNA_helicase PF00910.22 KKK23536.1 - 0.087 13.2 0.0 0.22 11.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Thymidylate_kin PF02223.17 KKK23536.1 - 0.16 11.7 0.4 0.5 10.0 0.1 2.1 2 0 0 2 2 2 0 Thymidylate kinase CbiA PF01656.23 KKK23536.1 - 0.25 11.4 0.6 1 9.4 0.6 2.2 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain KAP_NTPase PF07693.14 KKK23536.1 - 0.73 9.0 6.4 0.64 9.2 2.6 2.6 2 2 0 3 3 3 0 KAP family P-loop domain Pyr_redox_2 PF07992.14 KKK23537.1 - 1.1e-07 31.4 0.0 8.6e-06 25.2 0.0 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KKK23537.1 - 4e-05 23.6 0.0 0.013 15.5 0.0 2.7 2 1 0 2 2 2 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KKK23537.1 - 0.0011 19.1 0.0 0.0034 17.6 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.19 KKK23537.1 - 0.0012 17.3 0.0 0.018 13.5 0.0 2.6 3 1 0 3 3 3 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KKK23537.1 - 0.0081 15.4 0.0 0.14 11.3 0.0 2.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KKK23537.1 - 0.073 12.2 0.0 0.19 10.9 0.0 1.7 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.14 KKK23537.1 - 0.15 10.7 0.0 3.9 6.1 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein Arylsulfotran_2 PF14269.6 KKK23538.1 - 1.8e-45 155.6 0.0 2.5e-45 155.1 0.0 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Transketolase_C PF02780.20 KKK23538.1 - 3.8e-30 104.3 0.1 8.1e-30 103.3 0.0 1.6 2 0 0 2 2 2 1 Transketolase, C-terminal domain Transket_pyr PF02779.24 KKK23538.1 - 4.6e-19 68.8 3.0 2.9e-14 53.2 1.5 3.4 1 1 1 2 2 2 2 Transketolase, pyrimidine binding domain Arylsulfotrans PF05935.11 KKK23538.1 - 1.3e-14 53.9 0.8 3e-14 52.8 0.8 1.4 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) Transketolase_N PF00456.21 KKK23539.1 - 2.8e-121 404.5 0.0 1.4e-120 402.3 0.0 1.8 1 1 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 KKK23539.1 - 2.5e-39 134.8 0.1 5.4e-39 133.7 0.1 1.6 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KKK23539.1 - 1.8e-07 31.1 0.0 4.2e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain TPP_enzyme_C PF02775.21 KKK23539.1 - 2.1e-05 24.4 1.0 0.00048 19.9 0.6 2.9 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.6 KKK23539.1 - 2.9e-05 23.4 0.0 0.00046 19.5 0.0 2.1 1 1 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.20 KKK23539.1 - 0.00011 21.2 0.0 0.00021 20.4 0.0 1.4 1 0 0 1 1 1 1 Dehydrogenase E1 component ADH_N PF08240.12 KKK23540.1 - 3e-28 97.9 1.2 3e-28 97.9 1.2 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KKK23540.1 - 2.9e-14 53.2 0.0 4.3e-14 52.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KKK23540.1 - 2.2e-08 33.8 0.7 6.5e-07 29.0 0.6 2.8 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus Pyr_redox_2 PF07992.14 KKK23540.1 - 5e-05 22.7 0.2 0.00094 18.5 0.1 2.3 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase ADH_zinc_N_2 PF13602.6 KKK23540.1 - 0.00098 20.2 0.0 0.0029 18.7 0.0 1.8 1 1 1 2 2 2 1 Zinc-binding dehydrogenase AdoHcyase_NAD PF00670.21 KKK23540.1 - 0.11 12.6 0.1 0.26 11.3 0.1 1.6 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain TrkA_N PF02254.18 KKK23540.1 - 0.11 12.7 0.0 0.23 11.7 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Pyr_redox_3 PF13738.6 KKK23540.1 - 0.19 11.0 0.4 0.88 8.8 0.1 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Phosphoesterase PF04185.14 KKK23541.1 - 3.7e-70 236.9 0.0 4.7e-70 236.5 0.0 1.1 1 0 0 1 1 1 1 Phosphoesterase family Spc7_N PF15402.6 KKK23549.1 - 0 1306.2 66.9 0 1305.6 66.9 1.2 1 0 0 1 1 1 1 N-terminus of kinetochore NMS complex subunit Spc7 Spc7 PF08317.11 KKK23549.1 - 2.8e-128 427.2 7.0 2.8e-128 427.2 7.0 1.6 2 0 0 2 2 2 1 Spc7 kinetochore protein Sec8_exocyst PF04048.14 KKK23549.1 - 0.0075 16.2 2.2 0.019 14.8 2.2 1.6 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain Gp_dh_C PF02800.20 KKK23549.1 - 0.072 12.7 0.3 0.25 10.9 0.0 2.0 2 0 0 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Ribosomal_S17_N PF16205.5 KKK23550.1 - 1.4e-33 115.0 0.5 2.4e-33 114.3 0.5 1.4 1 0 0 1 1 1 1 Ribosomal_S17 N-terminal Ribosomal_S17 PF00366.20 KKK23550.1 - 7.7e-28 96.4 0.8 7.7e-28 96.4 0.8 1.6 2 0 0 2 2 2 1 Ribosomal protein S17 ANTH PF07651.16 KKK23552.1 - 3.7e-61 206.6 0.7 4.6e-61 206.3 0.7 1.1 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.20 KKK23552.1 - 1e-05 25.5 0.1 4.9e-05 23.4 0.0 2.0 2 0 0 2 2 2 1 ENTH domain Fungal_trans_2 PF11951.8 KKK23553.1 - 0.036 12.9 0.5 2 7.2 0.1 2.2 2 0 0 2 2 2 0 Fungal specific transcription factor domain Gpr1_Fun34_YaaH PF01184.19 KKK23554.1 - 2.1e-70 236.6 16.8 2.5e-70 236.3 16.8 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family zf-C3HC4_3 PF13920.6 KKK23564.1 - 0.00047 20.0 12.2 0.00075 19.3 12.2 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 KKK23564.1 - 2.7 7.9 6.2 4.7 7.2 6.2 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein DUF2379 PF09543.10 KKK23568.1 - 0.019 15.2 1.0 0.16 12.2 0.5 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2379) GW PF13457.6 KKK23568.1 - 0.13 12.9 0.0 2.6 8.7 0.0 2.4 2 0 0 2 2 2 0 GW (Gly-Tryp) dipeptide domain Ran_BP1 PF00638.18 KKK23569.1 - 2.5e-50 169.8 2.0 2.5e-50 169.8 2.0 1.5 2 0 0 2 2 2 1 RanBP1 domain WH1 PF00568.23 KKK23569.1 - 2e-05 24.5 0.3 0.00015 21.6 0.3 2.1 1 1 0 1 1 1 1 WH1 domain VID27_PH PF17747.1 KKK23569.1 - 0.0022 18.2 0.0 0.0033 17.7 0.0 1.2 1 0 0 1 1 1 1 VID27 PH-like domain DUF4358 PF14270.6 KKK23569.1 - 0.052 13.8 3.8 2.2 8.6 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4358) CDC27 PF09507.10 KKK23569.1 - 0.15 11.4 19.4 0.21 11.0 19.4 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Phasin PF05597.11 KKK23569.1 - 1.5 8.9 7.7 1.7 8.6 0.3 2.9 3 0 0 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF966 PF06136.13 KKK23569.1 - 6.8 6.3 9.8 8.6 6.0 9.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) YEATS PF03366.16 KKK23570.1 - 1.3e-18 66.7 0.0 2.3e-18 65.9 0.0 1.4 1 0 0 1 1 1 1 YEATS family BET PF17035.5 KKK23570.1 - 1.7e-05 24.9 0.1 2.8e-05 24.2 0.1 1.3 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation Fungal_trans PF04082.18 KKK23571.1 - 6.1e-19 68.1 0.0 1.5e-18 66.8 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.6 KKK23571.1 - 5.9e-06 26.5 6.2 5.9e-06 26.5 6.2 3.2 3 0 0 3 3 3 1 Zinc-finger double domain Zn_clus PF00172.18 KKK23571.1 - 1.2e-05 25.3 9.6 1.2e-05 25.3 9.6 2.5 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2 PF00096.26 KKK23571.1 - 3.1e-05 24.2 18.4 0.012 16.1 4.8 3.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KKK23571.1 - 0.0019 18.9 25.2 0.022 15.6 3.5 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KKK23571.1 - 0.0065 16.7 5.7 0.97 9.8 1.3 2.7 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KKK23571.1 - 0.01 16.2 0.7 0.026 14.9 0.7 1.8 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2HE PF16278.5 KKK23571.1 - 9 6.8 7.3 1.4e+02 3.0 7.2 2.6 1 1 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger DNA_ligase_A_M PF01068.21 KKK23574.1 - 1.2e-45 155.7 0.0 3.5e-45 154.2 0.0 1.8 2 0 0 2 2 2 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 KKK23574.1 - 8.7e-45 153.1 0.0 3e-43 148.1 0.0 2.7 2 1 0 2 2 2 1 DNA ligase N terminus BRCT_2 PF16589.5 KKK23574.1 - 1.2e-19 70.4 0.0 6e-14 52.2 0.0 2.7 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain DNA_ligase_A_C PF04679.15 KKK23574.1 - 1.4e-17 64.1 0.0 7.5e-16 58.5 0.0 3.2 3 0 0 3 3 3 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 KKK23574.1 - 6.3e-16 59.1 0.0 1.5e-15 57.9 0.0 1.7 1 0 0 1 1 1 1 RNA ligase BRCT PF00533.26 KKK23574.1 - 2.1e-11 44.0 0.0 1.6e-06 28.4 0.0 2.7 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 KKK23574.1 - 2.1e-07 31.1 0.0 0.0013 19.0 0.0 2.5 2 0 0 2 2 2 2 DNA ligase 3 BRCT domain DNA_ligase_IV PF11411.8 KKK23574.1 - 2.2e-05 24.5 0.1 4.5e-05 23.5 0.1 1.5 1 0 0 1 1 1 1 DNA ligase IV DUF1258 PF06869.12 KKK23574.1 - 0.16 11.5 0.0 0.28 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1258) RTA1 PF04479.13 KKK23575.1 - 5.9e-51 173.0 16.4 7.5e-51 172.7 16.4 1.1 1 0 0 1 1 1 1 RTA1 like protein Cyclin_N PF00134.23 KKK23575.1 - 0.13 12.0 0.4 0.21 11.4 0.4 1.3 1 0 0 1 1 1 0 Cyclin, N-terminal domain SLAC1 PF03595.17 KKK23575.1 - 0.22 10.7 20.4 1.6 7.9 8.7 2.2 1 1 1 2 2 2 0 Voltage-dependent anion channel Fungal_trans PF04082.18 KKK23576.1 - 5.9e-43 146.8 0.0 9.3e-43 146.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Acetyltransf_1 PF00583.25 KKK23577.1 - 2.1e-10 40.8 0.0 3.2e-10 40.3 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KKK23577.1 - 5.3e-09 36.1 0.0 8.8e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KKK23577.1 - 9.2e-08 32.4 0.0 1.9e-07 31.4 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KKK23577.1 - 0.047 13.8 0.0 0.094 12.8 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KKK23577.1 - 0.12 12.6 0.0 0.33 11.1 0.0 1.8 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase Fungal_trans PF04082.18 KKK23578.1 - 1e-07 31.3 0.8 0.00013 21.1 0.1 3.2 2 1 0 2 2 2 2 Fungal specific transcription factor domain COA2 PF17051.5 KKK23579.1 - 0.014 15.4 0.0 0.021 14.9 0.0 1.3 1 0 0 1 1 1 0 Cytochrome C oxidase assembly factor 2 Metallophos PF00149.28 KKK23580.1 - 3.3e-32 112.7 0.0 1.6e-22 81.0 0.0 2.2 1 1 1 2 2 2 2 Calcineurin-like phosphoesterase EamA PF00892.20 KKK23581.1 - 7.4e-10 39.1 38.2 2.6e-08 34.1 4.1 3.1 3 0 0 3 3 3 2 EamA-like transporter family DUF3955 PF13127.6 KKK23581.1 - 6.1e-08 32.4 1.1 4.2e-07 29.7 1.1 2.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3955) PUNUT PF16913.5 KKK23581.1 - 0.00013 21.3 0.8 0.00013 21.3 0.8 2.3 3 0 0 3 3 3 1 Purine nucleobase transmembrane transport UAA PF08449.11 KKK23581.1 - 0.00028 20.2 9.4 0.00028 20.2 9.4 1.6 2 0 0 2 2 2 1 UAA transporter family SLC35F PF06027.12 KKK23581.1 - 0.0027 17.3 11.2 0.0027 17.3 11.2 2.3 2 1 0 2 2 2 1 Solute carrier family 35 7tm_7 PF08395.12 KKK23581.1 - 0.033 13.4 0.5 0.033 13.4 0.5 3.4 4 0 0 4 4 4 0 7tm Chemosensory receptor Ras PF00071.22 KKK23582.1 - 7.4e-57 191.5 0.0 8.7e-57 191.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KKK23582.1 - 3e-32 111.3 0.0 4.4e-32 110.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKK23582.1 - 4.2e-13 49.1 0.0 5e-13 48.9 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KKK23582.1 - 2.3e-07 30.9 0.0 3.7e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KKK23582.1 - 1e-05 25.2 0.0 0.00053 19.6 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KKK23582.1 - 1.2e-05 24.8 0.0 1.5e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 KKK23582.1 - 0.00017 21.5 0.1 0.0043 17.0 0.1 2.3 1 1 2 3 3 3 1 RsgA GTPase PduV-EutP PF10662.9 KKK23582.1 - 0.0014 18.3 0.1 0.087 12.6 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.17 KKK23582.1 - 0.0022 17.8 0.2 0.065 13.0 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA_22 PF13401.6 KKK23582.1 - 0.0047 17.2 0.0 0.013 15.7 0.0 1.8 2 1 0 2 2 2 1 AAA domain Septin PF00735.18 KKK23582.1 - 0.0053 16.1 0.1 0.053 12.8 0.0 2.1 2 0 0 2 2 2 1 Septin cobW PF02492.19 KKK23582.1 - 0.0078 15.8 0.0 0.032 13.8 0.0 1.8 1 1 2 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.6 KKK23582.1 - 0.0094 16.3 0.0 0.016 15.6 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.6 KKK23582.1 - 0.013 15.2 0.0 0.023 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 KKK23582.1 - 0.017 15.1 0.0 0.029 14.4 0.0 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) SRPRB PF09439.10 KKK23582.1 - 0.017 14.5 0.0 0.021 14.3 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_7 PF12775.7 KKK23582.1 - 0.027 14.0 0.0 0.065 12.8 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region NTPase_1 PF03266.15 KKK23582.1 - 0.044 13.7 0.0 0.068 13.1 0.0 1.3 1 0 0 1 1 1 0 NTPase ATPase_2 PF01637.18 KKK23582.1 - 0.084 12.8 0.8 0.13 12.1 0.1 1.6 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea TniB PF05621.11 KKK23582.1 - 0.12 11.8 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein NACHT PF05729.12 KKK23582.1 - 0.16 11.9 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 NACHT domain NB-ARC PF00931.22 KKK23582.1 - 0.16 11.1 0.0 0.3 10.3 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain G-alpha PF00503.20 KKK23582.1 - 0.17 11.0 0.4 0.67 9.1 0.2 1.9 2 1 1 3 3 3 0 G-protein alpha subunit AAA_18 PF13238.6 KKK23582.1 - 0.18 12.3 0.0 0.36 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain ATG16 PF08614.11 KKK23583.1 - 9.6e-47 159.8 17.1 1.8e-44 152.4 17.1 2.0 1 1 0 1 1 1 1 Autophagy protein 16 (ATG16) DUF4201 PF13870.6 KKK23583.1 - 0.0031 17.3 9.2 0.0061 16.3 9.2 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4201) IFT57 PF10498.9 KKK23583.1 - 0.0054 15.8 2.0 0.007 15.4 2.0 1.1 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 EMP24_GP25L PF01105.24 KKK23583.1 - 0.017 15.1 0.8 0.74 9.7 0.0 2.1 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD DUF3450 PF11932.8 KKK23583.1 - 0.018 14.4 5.4 0.031 13.6 5.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) Golgin_A5 PF09787.9 KKK23583.1 - 0.021 14.3 5.6 0.024 14.1 5.6 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 Tropomyosin PF00261.20 KKK23583.1 - 0.029 13.7 10.3 0.081 12.3 10.5 1.6 1 1 0 1 1 1 0 Tropomyosin Spc7 PF08317.11 KKK23583.1 - 0.04 12.8 6.9 0.067 12.1 6.2 1.5 1 1 1 2 2 2 0 Spc7 kinetochore protein UPF0242 PF06785.11 KKK23583.1 - 0.042 14.0 8.0 0.037 14.2 3.8 2.0 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF4407 PF14362.6 KKK23583.1 - 0.055 12.8 7.9 0.076 12.4 7.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Prefoldin_2 PF01920.20 KKK23583.1 - 0.06 13.3 4.1 3.4 7.7 0.1 2.3 1 1 1 2 2 2 0 Prefoldin subunit Nbl1_Borealin_N PF10444.9 KKK23583.1 - 0.069 12.8 0.3 0.069 12.8 0.3 2.3 2 0 0 2 2 2 0 Nbl1 / Borealin N terminal DUF874 PF05917.11 KKK23583.1 - 0.072 12.1 1.1 0.094 11.7 1.1 1.1 1 0 0 1 1 1 0 Helicobacter pylori protein of unknown function (DUF874) Lebercilin PF15619.6 KKK23583.1 - 0.095 12.4 8.9 0.13 11.9 8.9 1.2 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease DHR10 PF18595.1 KKK23583.1 - 0.11 12.6 13.3 0.089 12.9 5.6 2.5 1 1 2 3 3 3 0 Designed helical repeat protein 10 domain FlaC_arch PF05377.11 KKK23583.1 - 0.12 12.8 1.3 16 6.0 0.1 2.6 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) Nup54 PF13874.6 KKK23583.1 - 0.12 12.5 6.8 1.9 8.6 1.2 2.2 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 BST2 PF16716.5 KKK23583.1 - 0.18 12.4 3.2 6.7 7.4 0.1 2.6 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 YabA PF06156.13 KKK23583.1 - 0.2 12.3 4.7 3.3 8.4 1.3 2.3 1 1 1 2 2 2 0 Initiation control protein YabA GAS PF13851.6 KKK23583.1 - 0.33 10.3 8.3 0.23 10.8 5.5 1.8 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding FAM76 PF16046.5 KKK23583.1 - 0.59 9.4 2.7 0.64 9.3 2.7 1.1 1 0 0 1 1 1 0 FAM76 protein Sec2p PF06428.11 KKK23583.1 - 0.73 9.8 7.8 0.86 9.6 5.7 2.2 2 1 0 2 2 2 0 GDP/GTP exchange factor Sec2p ABC_tran_CTD PF16326.5 KKK23583.1 - 1 9.7 9.2 4.5 7.6 6.3 3.2 1 1 1 2 2 2 0 ABC transporter C-terminal domain FliJ PF02050.16 KKK23583.1 - 1.4 9.2 10.2 0.41 10.9 0.5 2.6 2 1 1 3 3 2 0 Flagellar FliJ protein Fez1 PF06818.15 KKK23583.1 - 1.8 9.0 9.6 1.2 9.6 3.6 2.1 1 1 1 2 2 2 0 Fez1 DUF4200 PF13863.6 KKK23583.1 - 1.8 9.0 9.3 1.1 9.7 4.7 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) SlyX PF04102.12 KKK23583.1 - 2.5 8.8 7.6 11 6.7 2.2 2.7 1 1 1 2 2 2 0 SlyX DUF4140 PF13600.6 KKK23583.1 - 2.9 8.4 9.6 6.1 7.4 1.1 2.6 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) GrpE PF01025.19 KKK23583.1 - 4.2 7.0 7.5 4.9 6.8 0.2 2.2 1 1 1 2 2 2 0 GrpE CCDC-167 PF15188.6 KKK23583.1 - 5.1 7.5 11.8 33 4.9 11.2 2.2 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 DOT1 PF08123.13 KKK23584.1 - 3.3e-77 258.7 0.0 4.4e-77 258.2 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 CMAS PF02353.20 KKK23584.1 - 0.18 11.0 0.0 0.35 10.1 0.0 1.4 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Spb1_C PF07780.12 KKK23585.1 - 9.6e-84 280.2 25.8 9.6e-84 280.2 25.8 2.6 3 0 0 3 3 3 1 Spb1 C-terminal domain FtsJ PF01728.19 KKK23585.1 - 1.2e-56 191.7 0.0 2.3e-56 190.7 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF3381 PF11861.8 KKK23585.1 - 3.2e-50 170.1 8.6 3.2e-50 170.1 8.6 4.8 5 0 0 5 5 5 1 Domain of unknown function (DUF3381) Methyltransf_23 PF13489.6 KKK23585.1 - 0.015 15.1 0.0 0.041 13.7 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltr_RsmB-F PF01189.17 KKK23585.1 - 0.031 13.9 0.0 0.066 12.8 0.0 1.5 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F E1_FCCH PF16190.5 KKK23585.1 - 0.095 12.9 0.0 0.27 11.5 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin-activating enzyme E1 FCCH domain Fungal_trans PF04082.18 KKK23587.1 - 7.2e-05 21.9 0.4 7.2e-05 21.9 0.4 2.1 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK23587.1 - 0.021 15.0 9.6 0.057 13.6 9.6 1.8 1 1 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain EF-hand_4 PF12763.7 KKK23588.1 - 1.8e-05 24.6 0.1 4e-05 23.5 0.1 1.5 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand Glyco_transf_15 PF01793.16 KKK23589.1 - 6.7e-95 318.1 11.4 3.3e-94 315.8 11.4 1.8 1 1 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase PH PF00169.29 KKK23590.1 - 1.5e-29 102.5 0.8 5.6e-14 52.5 0.1 2.3 2 0 0 2 2 2 2 PH domain PH_11 PF15413.6 KKK23590.1 - 1e-11 45.1 0.8 0.00063 20.1 0.3 3.7 2 2 0 2 2 2 2 Pleckstrin homology domain PH_9 PF15410.6 KKK23590.1 - 1.7e-11 44.5 0.8 3.4e-06 27.4 0.1 4.0 2 2 0 2 2 2 2 Pleckstrin homology domain PH_2 PF08458.10 KKK23590.1 - 0.0005 20.4 0.1 0.011 16.1 0.0 2.7 2 1 0 2 2 2 1 Plant pleckstrin homology-like region PH_8 PF15409.6 KKK23590.1 - 0.0013 19.0 0.1 0.09 13.1 0.0 2.3 2 0 0 2 2 2 1 Pleckstrin homology domain PH_13 PF16652.5 KKK23590.1 - 0.0036 17.1 0.2 0.13 12.1 0.1 2.2 2 0 0 2 2 2 1 Pleckstrin homology domain PH_6 PF15406.6 KKK23590.1 - 0.024 14.9 0.0 0.72 10.2 0.0 2.6 3 0 0 3 3 3 0 Pleckstrin homology domain Mcp5_PH PF12814.7 KKK23590.1 - 0.1 12.7 0.2 7.7 6.7 0.0 2.7 3 0 0 3 3 3 0 Meiotic cell cortex C-terminal pleckstrin homology ALG3 PF05208.13 KKK23591.1 - 6.9e-143 476.4 10.7 8.1e-143 476.2 10.7 1.0 1 0 0 1 1 1 1 ALG3 protein eIF-1a PF01176.19 KKK23592.1 - 1.5e-16 59.9 0.0 2e-16 59.5 0.0 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 GnsAB_toxin PF08178.11 KKK23592.1 - 0.0088 15.9 0.0 0.015 15.2 0.0 1.3 1 0 0 1 1 1 1 GnsA/GnsB toxin of bacterial toxin-antitoxin system Peptidase_M20 PF01546.28 KKK23598.1 - 2.2e-17 63.4 0.0 2.7e-17 63.2 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KKK23598.1 - 2.1e-05 24.4 0.0 3.2e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain MMR_HSR1 PF01926.23 KKK23599.1 - 1.5e-05 25.0 0.0 0.0015 18.6 0.0 2.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase ATPase-cat_bd PF12156.8 KKK23599.1 - 0.0016 19.2 0.2 0.0041 17.8 0.2 1.6 1 0 0 1 1 1 1 Putative metal-binding domain of cation transport ATPase RsgA_GTPase PF03193.16 KKK23599.1 - 0.0092 15.9 0.2 0.024 14.5 0.0 1.8 2 0 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 KKK23599.1 - 0.013 15.5 0.0 3.5 7.6 0.2 2.9 1 1 1 2 2 2 0 Dynamin family Mrpl_C PF18502.1 KKK23599.1 - 0.13 12.6 0.2 9.1 6.6 0.1 2.7 2 0 0 2 2 2 0 54S ribosomal protein L8 C-terminal domain tRNA-synt_1 PF00133.22 KKK23600.1 - 9.9e-37 126.5 0.0 2.2e-25 89.0 0.0 2.8 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 KKK23600.1 - 5.4e-17 61.6 0.0 3.7e-10 39.1 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 KKK23600.1 - 6.5e-15 55.4 0.2 1.6e-14 54.2 0.2 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 KKK23600.1 - 1.5e-07 31.1 0.0 3.6e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1b PF00579.25 KKK23600.1 - 0.24 10.7 1.4 1.9 7.7 0.0 2.5 2 1 1 3 3 3 0 tRNA synthetases class I (W and Y) S10_plectin PF03501.15 KKK23601.1 - 4.3e-42 142.1 0.1 5.6e-42 141.7 0.1 1.1 1 0 0 1 1 1 1 Plectin/S10 domain tRNA-synt_1c_C PF03950.18 KKK23601.1 - 0.047 13.6 0.0 0.057 13.3 0.0 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (E and Q), anti-codon binding domain Sde2_N_Ubi PF13019.6 KKK23602.1 - 6.8e-69 230.9 0.3 1.2e-68 230.1 0.3 1.4 1 0 0 1 1 1 1 Silencing defective 2 N-terminal ubiquitin domain Rotamase_2 PF13145.6 KKK23602.1 - 0.037 14.9 1.6 0.076 13.9 1.6 1.4 1 0 0 1 1 1 0 PPIC-type PPIASE domain CDC24 PF06395.11 KKK23603.1 - 2.7e-31 107.7 0.0 8e-31 106.2 0.0 1.8 2 0 0 2 2 2 1 CDC24 Calponin RhoGEF PF00621.20 KKK23603.1 - 3.2e-28 99.2 0.7 5.3e-28 98.5 0.7 1.3 1 0 0 1 1 1 1 RhoGEF domain DUF4404 PF14357.6 KKK23603.1 - 0.98 10.1 5.0 3.4 8.4 0.5 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) WD40 PF00400.32 KKK23604.1 - 1.5e-28 98.5 12.9 0.00014 22.5 0.0 7.8 8 0 0 8 8 8 5 WD domain, G-beta repeat F-box-like PF12937.7 KKK23604.1 - 5.6e-13 48.6 0.4 1.6e-12 47.1 0.4 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KKK23604.1 - 7.1e-08 32.1 0.3 1.6e-07 31.0 0.3 1.7 1 0 0 1 1 1 1 F-box domain ANAPC4_WD40 PF12894.7 KKK23604.1 - 3.7e-05 24.0 0.5 0.86 9.9 0.0 3.8 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KKK23604.1 - 0.00073 18.3 1.1 0.46 9.1 0.4 2.6 2 1 0 2 2 2 2 Nucleoporin Nup120/160 BBS2_Mid PF14783.6 KKK23604.1 - 0.039 14.0 0.1 54 3.9 0.0 4.9 5 2 1 6 6 6 0 Ciliary BBSome complex subunit 2, middle region Peptidase_M48 PF01435.18 KKK23604.1 - 0.049 13.4 0.1 0.099 12.4 0.1 1.4 1 0 0 1 1 1 0 Peptidase family M48 MID_MedPIWI PF18296.1 KKK23604.1 - 0.21 11.3 5.4 0.8 9.4 4.3 2.0 2 0 0 2 2 2 0 MID domain of medPIWI SPX PF03105.19 KKK23604.1 - 6.7 6.5 17.6 6.9 6.5 0.6 2.2 2 0 0 2 2 2 0 SPX domain MFS_2 PF13347.6 KKK23605.1 - 1.2e-08 34.0 5.5 1.2e-08 34.0 5.5 2.3 2 0 0 2 2 2 2 MFS/sugar transport protein Na_H_Exchanger PF00999.21 KKK23607.1 - 1.2e-68 231.7 39.7 1.5e-68 231.3 39.7 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF4396 PF14342.6 KKK23607.1 - 1.1 9.7 8.7 7.5 6.9 2.5 3.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4396) AA_permease_2 PF13520.6 KKK23608.1 - 7.8e-62 209.5 42.5 1.1e-61 209.0 42.5 1.1 1 0 0 1 1 1 1 Amino acid permease DUF4064 PF13273.6 KKK23609.1 - 0.016 15.5 0.5 0.019 15.2 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) His_biosynth PF00977.21 KKK23610.1 - 8.7e-33 113.7 0.0 1.2e-32 113.3 0.0 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein DUF4602 PF15375.6 KKK23611.1 - 1e-11 45.3 31.8 1.8e-10 41.2 31.8 2.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4602) Nop25 PF09805.9 KKK23611.1 - 0.0023 18.4 10.1 0.0023 18.4 10.1 3.0 2 1 0 2 2 2 1 Nucleolar protein 12 (25kDa) PI3K_1B_p101 PF10486.9 KKK23611.1 - 2.6 5.7 10.3 3.5 5.3 10.3 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit STE PF02200.16 KKK23612.1 - 1.5e-56 189.5 0.1 2.4e-56 188.9 0.1 1.3 1 0 0 1 1 1 1 STE like transcription factor zf-C2H2 PF00096.26 KKK23612.1 - 2.5e-11 43.4 9.8 1.1e-06 28.8 0.5 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KKK23612.1 - 6.2e-09 35.9 4.1 6.2e-09 35.9 4.1 3.2 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KKK23612.1 - 7.1e-08 32.6 7.8 0.00081 20.0 0.3 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KKK23612.1 - 0.00071 19.5 3.9 0.0012 18.8 0.1 2.4 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KKK23612.1 - 0.015 15.6 0.1 0.24 11.7 0.0 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zinc_ribbon_9 PF14369.6 KKK23612.1 - 0.091 13.0 0.2 0.23 11.8 0.2 1.7 1 0 0 1 1 1 0 zinc-ribbon zf-TRAF PF02176.18 KKK23612.1 - 0.17 12.6 2.6 0.29 11.8 2.6 1.4 1 0 0 1 1 1 0 TRAF-type zinc finger NOA36 PF06524.12 KKK23612.1 - 0.24 10.7 0.1 0.39 10.0 0.1 1.2 1 0 0 1 1 1 0 NOA36 protein zf-Di19 PF05605.12 KKK23612.1 - 0.44 10.9 3.3 1.2 9.5 3.3 1.7 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2HC_2 PF13913.6 KKK23612.1 - 1.3 9.0 5.5 1.5 8.8 0.3 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-H2C2_5 PF13909.6 KKK23612.1 - 5.9 6.7 9.6 28 4.6 3.0 3.2 3 0 0 3 3 3 0 C2H2-type zinc-finger domain TPR_21 PF09976.9 KKK23613.1 - 0.092 12.4 0.1 0.18 11.5 0.1 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat-like domain RFX_DNA_binding PF02257.15 KKK23614.1 - 9e-28 96.7 0.2 2.1e-27 95.5 0.2 1.7 1 0 0 1 1 1 1 RFX DNA-binding domain YL1 PF05764.13 KKK23615.1 - 0.00035 20.8 9.5 0.00035 20.8 9.5 2.2 2 0 0 2 2 2 1 YL1 nuclear protein CDC45 PF02724.14 KKK23615.1 - 0.00054 18.4 7.1 0.0011 17.4 7.1 1.4 1 0 0 1 1 1 1 CDC45-like protein SDA1 PF05285.12 KKK23615.1 - 0.083 12.3 8.8 0.15 11.4 8.8 1.4 1 0 0 1 1 1 0 SDA1 MFAP1 PF06991.11 KKK23615.1 - 0.15 11.9 9.7 0.07 13.0 3.8 2.3 2 0 0 2 2 2 0 Microfibril-associated/Pre-mRNA processing FAM176 PF14851.6 KKK23615.1 - 1.3 8.7 7.9 3.9 7.1 7.9 1.9 1 0 0 1 1 1 0 FAM176 family PPP4R2 PF09184.11 KKK23615.1 - 1.6 8.3 11.9 2.8 7.4 11.9 1.3 1 0 0 1 1 1 0 PPP4R2 NOA36 PF06524.12 KKK23615.1 - 2.5 7.3 23.3 4.5 6.5 23.3 1.3 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 KKK23615.1 - 2.8 5.9 21.5 4.3 5.3 21.5 1.2 1 0 0 1 1 1 0 DNA polymerase phi Tom22 PF04281.13 KKK23615.1 - 3.3 7.5 11.5 8.3 6.2 11.5 1.7 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 BUD22 PF09073.10 KKK23615.1 - 3.7 6.8 15.9 7.3 5.8 15.9 1.5 1 0 0 1 1 1 0 BUD22 DUF4407 PF14362.6 KKK23615.1 - 4.3 6.6 4.8 17 4.7 0.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Nop14 PF04147.12 KKK23615.1 - 4.9 5.2 18.7 0.097 10.9 12.0 1.5 2 0 0 2 2 2 0 Nop14-like family RXT2_N PF08595.11 KKK23615.1 - 6.6 6.7 12.0 17 5.4 12.0 1.7 1 0 0 1 1 1 0 RXT2-like, N-terminal RRN3 PF05327.11 KKK23615.1 - 6.7 5.1 13.2 10 4.5 13.2 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Vfa1 PF08432.10 KKK23615.1 - 7.7 6.8 8.0 0.25 11.7 1.7 1.7 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 GCIP PF13324.6 KKK23615.1 - 8.8 5.8 9.0 16 5.0 9.0 1.4 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting ThiF PF00899.21 KKK23616.1 - 2.3e-31 109.0 0.0 3e-31 108.6 0.0 1.1 1 0 0 1 1 1 1 ThiF family Ytp1 PF10355.9 KKK23617.1 - 1.5e-72 244.1 16.8 1.5e-72 244.1 16.8 2.3 2 1 0 2 2 2 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 KKK23617.1 - 6.2e-33 112.7 0.9 6.2e-33 112.7 0.9 3.0 3 0 0 3 3 3 1 Domain of unknown function (DUF2427) Zip PF02535.22 KKK23617.1 - 0.0001 21.6 1.9 0.15 11.3 0.0 2.8 2 0 0 2 2 2 2 ZIP Zinc transporter ExoD PF06055.12 KKK23617.1 - 0.0082 15.5 0.3 0.0082 15.5 0.3 2.9 4 0 0 4 4 4 1 Exopolysaccharide synthesis, ExoD DUF3180 PF11377.8 KKK23617.1 - 0.073 13.2 7.3 3.6 7.7 5.2 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF3180) Swi5 PF07061.11 KKK23618.1 - 2.1e-28 98.2 1.3 2.1e-28 98.2 1.3 1.7 1 1 1 2 2 2 1 Swi5 Cortex-I_coil PF09304.10 KKK23618.1 - 0.014 15.6 1.6 0.021 15.0 1.0 1.6 1 1 1 2 2 2 0 Cortexillin I, coiled coil STIL_N PF15253.6 KKK23618.1 - 0.061 12.3 3.9 0.075 12.0 3.9 1.1 1 0 0 1 1 1 0 SCL-interrupting locus protein N-terminus Atg14 PF10186.9 KKK23618.1 - 0.096 11.7 2.5 0.1 11.6 2.5 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 GCIP PF13324.6 KKK23618.1 - 0.12 12.0 3.1 0.16 11.6 3.1 1.1 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting ABC_tran PF00005.27 KKK23619.1 - 2.5e-12 47.5 0.0 4.3e-12 46.7 0.0 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KKK23619.1 - 0.00014 21.4 0.1 0.00018 21.0 0.1 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 KKK23619.1 - 0.014 15.7 1.7 0.25 11.6 1.5 2.4 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Radical_SAM_C PF16199.5 KKK23620.1 - 8.5e-33 112.2 0.0 1.9e-32 111.1 0.0 1.6 1 0 0 1 1 1 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 KKK23620.1 - 2.5e-20 73.5 0.1 1e-19 71.5 0.0 2.0 2 0 0 2 2 2 1 Radical SAM superfamily Acetyltransf_1 PF00583.25 KKK23620.1 - 1.9e-10 41.0 0.0 3.5e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KKK23620.1 - 9e-06 25.6 0.0 3.5e-05 23.8 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain CoA_binding PF02629.19 KKK23621.1 - 2.2e-26 92.4 4.0 3.1e-26 91.9 1.5 2.1 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 KKK23621.1 - 4.1e-23 81.9 0.2 6.8e-23 81.2 0.2 1.4 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 KKK23621.1 - 2.2e-07 30.8 0.1 4.1e-07 29.9 0.1 1.5 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 KKK23621.1 - 0.00038 20.9 0.1 0.00087 19.8 0.1 1.6 1 0 0 1 1 1 1 CoA binding domain Aldedh PF00171.22 KKK23623.1 - 1.3e-135 452.5 0.3 1.6e-135 452.2 0.3 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 KKK23623.1 - 0.062 12.3 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) Yos1 PF08571.10 KKK23624.1 - 5.8e-08 32.9 0.0 9.1e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 Yos1-like UCH PF00443.29 KKK23625.1 - 1.5e-57 195.0 0.1 3.1e-57 194.0 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KKK23625.1 - 2.3e-26 93.2 0.7 2.1e-19 70.3 0.0 2.4 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 KKK23625.1 - 0.0056 16.2 4.8 0.044 13.2 2.1 2.7 3 0 0 3 3 3 1 Ubiquitin-specific peptidase-like, SUMO isopeptidase Dynamitin PF04912.14 KKK23626.1 - 6.9e-76 256.1 20.0 1.3e-40 139.9 8.5 2.1 2 0 0 2 2 2 2 Dynamitin Laminin_II PF06009.12 KKK23626.1 - 0.022 14.8 0.1 0.022 14.8 0.1 3.9 4 2 1 5 5 4 0 Laminin Domain II CLZ PF16526.5 KKK23626.1 - 0.023 15.0 21.8 24 5.4 4.1 6.4 5 2 2 7 7 6 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels AKNA PF12443.8 KKK23626.1 - 0.028 15.1 0.4 0.028 15.1 0.4 2.8 3 0 0 3 3 1 0 AT-hook-containing transcription factor DUF4407 PF14362.6 KKK23626.1 - 0.055 12.8 21.9 0.3 10.4 9.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) LPP PF04728.13 KKK23626.1 - 0.07 13.5 8.9 0.42 11.0 0.3 4.3 3 1 0 3 3 3 0 Lipoprotein leucine-zipper CorA PF01544.18 KKK23626.1 - 0.12 11.7 9.5 0.019 14.3 3.3 2.2 2 1 0 2 2 2 0 CorA-like Mg2+ transporter protein DUF1664 PF07889.12 KKK23626.1 - 0.14 12.2 8.4 3 7.9 0.2 3.9 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) PhaP_Bmeg PF09602.10 KKK23626.1 - 0.41 10.6 4.6 1.5 8.7 0.2 2.9 2 1 1 3 3 3 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) Tmemb_cc2 PF10267.9 KKK23626.1 - 0.67 9.0 18.9 5.5e+02 -0.6 18.9 2.5 1 1 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Phage_Mu_Gam PF07352.12 KKK23626.1 - 0.69 9.8 6.5 7.1 6.5 0.1 3.0 3 0 0 3 3 3 0 Bacteriophage Mu Gam like protein Prefoldin PF02996.17 KKK23626.1 - 0.79 9.6 12.5 5.4 6.9 0.0 4.7 3 2 2 5 5 5 0 Prefoldin subunit FapA PF03961.13 KKK23626.1 - 0.83 8.2 7.9 1.8 7.1 0.9 2.2 2 0 0 2 2 2 0 Flagellar Assembly Protein A Vps51 PF08700.11 KKK23626.1 - 1.5 9.0 5.1 12 6.1 0.0 3.6 4 0 0 4 4 3 0 Vps51/Vps67 DUF16 PF01519.16 KKK23626.1 - 1.8 9.1 6.1 8.9 6.9 0.4 3.3 2 1 1 3 3 3 0 Protein of unknown function DUF16 Prefoldin_2 PF01920.20 KKK23626.1 - 2.1 8.4 14.3 0.42 10.6 0.8 3.7 3 1 0 3 3 3 0 Prefoldin subunit Fib_alpha PF08702.10 KKK23626.1 - 2.3 8.4 9.8 13 6.0 1.5 3.6 2 2 2 4 4 4 0 Fibrinogen alpha/beta chain family DHR10 PF18595.1 KKK23626.1 - 2.4 8.2 23.3 0.036 14.1 2.6 3.9 2 1 1 3 3 3 0 Designed helical repeat protein 10 domain DMPK_coil PF08826.10 KKK23626.1 - 2.6 8.2 12.5 3.2 7.9 0.1 3.6 2 1 1 3 3 3 0 DMPK coiled coil domain like EMP24_GP25L PF01105.24 KKK23626.1 - 2.8 7.9 5.9 0.95 9.4 1.2 2.3 2 1 0 2 2 2 0 emp24/gp25L/p24 family/GOLD Fmp27_WPPW PF10359.9 KKK23626.1 - 4.2 6.1 15.9 2.7 6.8 4.2 2.9 3 0 0 3 3 3 0 RNA pol II promoter Fmp27 protein domain DivIC PF04977.15 KKK23626.1 - 7.4 6.4 15.8 0.63 9.9 0.2 3.6 4 0 0 4 4 3 0 Septum formation initiator 5_nucleotid PF05761.14 KKK23626.1 - 8.6 5.1 8.6 0.33 9.8 1.1 2.0 2 1 0 2 2 2 0 5' nucleotidase family Jnk-SapK_ap_N PF09744.9 KKK23626.1 - 8.6 6.6 23.7 0.064 13.5 1.5 3.2 2 1 1 3 3 3 0 JNK_SAPK-associated protein-1 GAS PF13851.6 KKK23626.1 - 9 5.6 14.9 3.6 6.9 0.5 3.1 2 2 0 3 3 3 0 Growth-arrest specific micro-tubule binding Glyco_transf_22 PF03901.17 KKK23627.1 - 6.7e-38 131.0 13.8 8e-38 130.7 13.8 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family LapA_dom PF06305.11 KKK23627.1 - 7.8 6.4 6.1 19 5.1 0.1 3.2 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain PX PF00787.24 KKK23628.1 - 2.7e-19 69.2 0.4 6e-19 68.1 0.4 1.5 1 0 0 1 1 1 1 PX domain Vps5 PF09325.10 KKK23628.1 - 3e-14 53.1 6.9 5.3e-07 29.4 0.4 2.1 2 0 0 2 2 2 2 Vps5 C terminal like BAR PF03114.18 KKK23628.1 - 0.00057 19.6 3.7 0.043 13.4 3.7 2.4 1 1 0 1 1 1 1 BAR domain Sec34 PF04136.15 KKK23628.1 - 0.017 15.0 1.2 0.023 14.6 0.1 1.8 2 0 0 2 2 2 0 Sec34-like family Laminin_II PF06009.12 KKK23628.1 - 0.32 11.0 3.0 0.4 10.7 0.2 2.3 2 1 1 3 3 3 0 Laminin Domain II Occludin_ELL PF07303.13 KKK23628.1 - 0.38 11.5 3.3 3.5 8.4 0.0 3.2 3 0 0 3 3 3 0 Occludin homology domain DUF1664 PF07889.12 KKK23628.1 - 1.3 9.1 5.8 6.9 6.7 0.3 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Troponin PF00992.20 KKK23628.1 - 2.1 8.6 8.1 1.2 9.4 0.3 2.6 3 0 0 3 3 3 0 Troponin Peptidase_S8 PF00082.22 KKK23629.1 - 4.7e-36 124.6 1.3 7.8e-36 123.9 1.3 1.3 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 KKK23629.1 - 1.6e-27 95.4 1.3 3.1e-27 94.4 1.3 1.5 1 0 0 1 1 1 1 Proprotein convertase P-domain S8_pro-domain PF16470.5 KKK23629.1 - 0.08 13.7 0.0 0.21 12.4 0.0 1.7 1 0 0 1 1 1 0 Peptidase S8 pro-domain FAD_binding_3 PF01494.19 KKK23630.1 - 1e-18 67.8 0.5 3.3e-16 59.5 0.5 2.9 1 1 0 1 1 1 1 FAD binding domain SE PF08491.10 KKK23630.1 - 1.6e-06 27.4 0.0 2.9e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Squalene epoxidase Lycopene_cycl PF05834.12 KKK23630.1 - 0.00046 19.3 0.1 0.0018 17.4 0.0 1.9 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_9 PF13454.6 KKK23630.1 - 0.0013 18.7 0.0 0.0031 17.5 0.0 1.6 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 KKK23630.1 - 0.0051 16.1 0.0 0.0074 15.6 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KKK23630.1 - 0.022 15.0 0.0 0.063 13.5 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 KKK23630.1 - 0.062 12.4 0.0 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.14 KKK23630.1 - 0.1 11.3 0.1 0.17 10.5 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein Thi4 PF01946.17 KKK23630.1 - 0.12 11.5 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 Thi4 family LSM PF01423.22 KKK23644.1 - 4.9e-14 51.8 1.3 1.3e-13 50.4 1.3 1.7 1 1 0 1 1 1 1 LSM domain ATP13 PF12921.7 KKK23645.1 - 3.1e-26 91.5 0.0 6.8e-26 90.4 0.0 1.6 1 0 0 1 1 1 1 Mitochondrial ATPase expression PPR_3 PF13812.6 KKK23645.1 - 0.00018 21.5 0.0 0.0017 18.4 0.0 2.3 2 0 0 2 2 2 1 Pentatricopeptide repeat domain PPR_2 PF13041.6 KKK23645.1 - 0.0059 16.8 0.0 0.68 10.2 0.0 2.8 2 0 0 2 2 2 1 PPR repeat family GTP_EFTU PF00009.27 KKK23646.1 - 3.4e-19 69.2 0.1 1.4e-18 67.2 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 KKK23646.1 - 4e-06 27.1 0.8 1.3e-05 25.5 0.8 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D3 PF03143.17 KKK23646.1 - 4.8e-05 23.6 0.0 0.00012 22.3 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain PduV-EutP PF10662.9 KKK23646.1 - 0.0082 15.9 1.0 0.47 10.2 0.1 3.1 2 1 1 3 3 3 1 Ethanolamine utilisation - propanediol utilisation RsgA_GTPase PF03193.16 KKK23646.1 - 0.024 14.6 0.3 3.4 7.6 0.0 2.8 2 0 0 2 2 2 0 RsgA GTPase MMR_HSR1 PF01926.23 KKK23646.1 - 0.032 14.3 0.5 0.086 12.9 0.1 2.1 2 1 0 2 2 2 0 50S ribosome-binding GTPase tRNA-synt_His PF13393.6 KKK23647.1 - 1.7e-43 149.1 0.0 1.1e-36 126.7 0.0 2.0 2 0 0 2 2 2 2 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 KKK23647.1 - 6.2e-12 45.5 0.0 1.3e-11 44.5 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain Glyoxalase_2 PF12681.7 KKK23647.1 - 0.024 14.6 0.0 0.046 13.6 0.0 1.5 1 0 0 1 1 1 0 Glyoxalase-like domain tRNA-synt_2 PF00152.20 KKK23647.1 - 0.035 13.2 0.0 0.2 10.7 0.0 2.1 1 1 0 1 1 1 0 tRNA synthetases class II (D, K and N) Transp_cyt_pur PF02133.15 KKK23654.1 - 5.5e-21 74.9 36.5 8.6e-21 74.2 36.5 1.2 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin COX5B PF01215.19 KKK23655.1 - 4.9e-54 181.5 0.0 6.5e-54 181.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb Myb_DNA-binding PF00249.31 KKK23656.1 - 2.2e-15 56.5 3.9 5.2e-09 36.2 0.7 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KKK23656.1 - 3.9e-09 36.6 1.2 9.5e-06 25.8 0.1 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 KKK23656.1 - 0.039 13.8 0.6 0.062 13.2 0.6 1.4 1 0 0 1 1 1 0 Myb DNA-binding like Ribosomal_L34e PF01199.18 KKK23657.1 - 3.7e-44 148.9 1.8 5e-44 148.5 1.8 1.2 1 0 0 1 1 1 1 Ribosomal protein L34e Vps36-NZF-N PF16988.5 KKK23657.1 - 0.028 13.8 0.0 0.053 12.9 0.0 1.6 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Myb_DNA-bind_6 PF13921.6 KKK23658.1 - 6.1e-13 48.8 0.0 5.1e-09 36.2 0.0 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KKK23658.1 - 4.3e-11 42.8 0.1 5.5e-05 23.3 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain HTH_32 PF13565.6 KKK23658.1 - 0.063 13.9 0.1 0.25 12.0 0.0 2.0 1 1 1 2 2 2 0 Homeodomain-like domain SANT_DAMP1_like PF16282.5 KKK23658.1 - 0.2 11.9 0.6 5.1 7.4 0.3 2.2 1 1 1 2 2 2 0 SANT/Myb-like domain of DAMP1 PROCN PF08083.11 KKK23659.1 - 8.9e-236 782.2 8.9 8.9e-236 782.2 8.9 2.0 2 0 0 2 2 2 1 PROCN (NUC071) domain PRP8_domainIV PF12134.8 KKK23659.1 - 1.2e-125 417.7 1.3 2.1e-125 416.9 1.3 1.4 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.9 KKK23659.1 - 6.7e-85 282.9 1.9 1.1e-57 194.5 0.3 3.1 2 0 0 2 2 2 2 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.11 KKK23659.1 - 7.9e-80 266.2 2.1 7.9e-80 266.2 2.1 1.9 2 0 0 2 2 2 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.9 KKK23659.1 - 1.3e-71 238.9 0.1 3.6e-71 237.5 0.1 1.8 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 RRM_4 PF10598.9 KKK23659.1 - 1.1e-47 160.3 0.3 3.1e-47 158.8 0.3 1.9 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 PROCT PF08084.11 KKK23659.1 - 7.4e-47 158.3 0.0 2e-46 156.9 0.0 1.8 1 0 0 1 1 1 1 PROCT (NUC072) domain Hom_end_hint PF05203.16 KKK23659.1 - 2.3e-11 44.1 0.1 8e-11 42.3 0.0 1.9 2 0 0 2 2 2 1 Hom_end-associated Hint Vint PF14623.6 KKK23659.1 - 0.034 14.0 0.0 0.38 10.5 0.0 2.5 3 0 0 3 3 3 0 Hint-domain FTR1 PF03239.14 KKK23676.1 - 1.7e-92 309.9 1.5 2e-92 309.7 1.5 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family Peptidase_U4 PF03419.13 KKK23676.1 - 0.009 15.3 0.4 0.009 15.3 0.4 2.2 2 1 0 2 2 2 1 Sporulation factor SpoIIGA DUF1467 PF07330.12 KKK23676.1 - 0.4 10.6 5.4 2.6 8.1 0.0 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF1467) PHO4 PF01384.20 KKK23676.1 - 2.4 7.1 8.0 19 4.2 0.7 2.3 1 1 1 2 2 2 0 Phosphate transporter family Cu-oxidase_2 PF07731.14 KKK23677.1 - 3.8e-43 146.5 8.2 1.7e-40 137.9 0.6 3.8 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 KKK23677.1 - 1.5e-40 137.9 10.6 4e-39 133.3 1.8 3.7 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 KKK23677.1 - 1.7e-36 125.7 6.3 1.3e-35 122.8 0.6 3.4 3 1 0 3 3 3 1 Multicopper oxidase DUF5060 PF16586.5 KKK23677.1 - 0.052 13.9 0.2 0.29 11.5 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5060) SUR7 PF06687.12 KKK23677.1 - 1.4 8.5 5.9 7.7 6.1 0.3 2.3 2 0 0 2 2 2 0 SUR7/PalI family Abhydrolase_3 PF07859.13 KKK23678.1 - 1.2e-66 224.6 0.1 1.6e-66 224.2 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KKK23678.1 - 3.6e-08 32.7 0.0 7.4e-08 31.7 0.0 1.4 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 KKK23678.1 - 2.9e-07 30.2 0.0 5.9e-07 29.2 0.0 1.4 1 1 0 1 1 1 1 Prolyl oligopeptidase family Say1_Mug180 PF10340.9 KKK23678.1 - 0.0054 15.6 0.0 0.016 14.0 0.0 1.9 2 0 0 2 2 2 1 Steryl acetyl hydrolase PhzC-PhzF PF02567.16 KKK23678.1 - 0.16 11.4 0.0 0.28 10.6 0.0 1.3 1 0 0 1 1 1 0 Phenazine biosynthesis-like protein PhoD PF09423.10 KKK23679.1 - 3.1e-37 128.4 0.0 1.4e-36 126.3 0.0 2.0 1 1 0 1 1 1 1 PhoD-like phosphatase Glyco_hydro_18 PF00704.28 KKK23679.1 - 1.1e-11 45.1 0.0 1.9e-11 44.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Fez1 PF06818.15 KKK23680.1 - 0.0019 18.7 16.6 0.0019 18.7 16.6 5.0 1 1 3 4 4 4 2 Fez1 KASH_CCD PF14662.6 KKK23680.1 - 5.7 6.7 75.5 0.57 10.0 25.8 3.5 2 1 1 3 3 3 0 Coiled-coil region of CCDC155 or KASH LSM PF01423.22 KKK23682.1 - 3.8e-12 45.7 0.1 5.8e-12 45.1 0.1 1.2 1 0 0 1 1 1 1 LSM domain Uds1 PF15456.6 KKK23682.1 - 0.073 13.2 0.1 0.082 13.1 0.1 1.1 1 0 0 1 1 1 0 Up-regulated During Septation Bac_export_2 PF01312.19 KKK23683.1 - 0.22 10.7 1.4 0.34 10.1 1.4 1.2 1 0 0 1 1 1 0 FlhB HrpN YscU SpaS Family UL42 PF17638.2 KKK23683.1 - 0.57 10.2 2.2 1 9.3 2.2 1.4 1 0 0 1 1 1 0 HCMV UL42 FtsL PF04999.13 KKK23683.1 - 6.4 6.8 6.3 2.9 8.0 2.6 2.0 1 1 1 2 2 2 0 Cell division protein FtsL Sugar_tr PF00083.24 KKK23684.1 - 5.6e-128 427.6 23.3 6.4e-128 427.4 23.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKK23684.1 - 4.1e-24 85.2 54.4 5.3e-21 74.9 28.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KKK23684.1 - 5.4e-07 28.8 0.0 3.1e-06 26.3 0.0 2.5 1 1 0 1 1 1 1 MFS_1 like family Ilm1 PF10311.9 KKK23684.1 - 0.13 11.9 0.7 0.23 11.1 0.7 1.4 1 0 0 1 1 1 0 Increased loss of mitochondrial DNA protein 1 MSP1b PF03429.13 KKK23684.1 - 0.18 9.9 0.4 0.26 9.3 0.4 1.1 1 0 0 1 1 1 0 Major surface protein 1B Cation_efflux PF01545.21 KKK23685.1 - 5.8e-54 182.9 0.2 9.3e-54 182.2 0.2 1.3 1 1 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 KKK23685.1 - 0.0056 16.8 0.5 0.011 15.8 0.5 1.4 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter MFS_1 PF07690.16 KKK23686.1 - 3.3e-33 115.1 41.8 3.3e-33 115.1 41.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KKK23686.1 - 2.3e-13 49.8 9.2 2.3e-13 49.8 9.2 2.3 2 1 0 2 2 2 1 Sugar (and other) transporter HATPase_c PF02518.26 KKK23687.1 - 9.1e-27 93.8 0.0 4.6e-26 91.5 0.0 2.1 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KKK23687.1 - 2.6e-24 85.5 1.4 5.3e-24 84.5 0.4 2.0 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 KKK23687.1 - 5.8e-15 55.1 0.0 1.8e-14 53.5 0.0 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 KKK23687.1 - 0.0015 18.8 0.7 0.2 12.0 0.0 2.8 2 0 0 2 2 2 1 HAMP domain IFT57 PF10498.9 KKK23687.1 - 0.13 11.2 1.9 0.24 10.4 1.9 1.3 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Abhydro_lipase PF04083.16 KKK23688.1 - 2e-22 78.5 0.0 4.6e-22 77.4 0.0 1.6 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 KKK23688.1 - 3.9e-06 26.7 0.2 8.6e-06 25.6 0.1 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KKK23688.1 - 0.00078 18.8 0.1 0.0021 17.4 0.0 1.7 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Metallophos PF00149.28 KKK23689.1 - 0.00049 20.7 2.9 0.0016 19.0 2.9 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Glyco_hydro_61 PF03443.14 KKK23691.1 - 2.2e-59 200.8 1.3 4.8e-59 199.8 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolase family 61 CBM_1 PF00734.18 KKK23691.1 - 1.3e-12 47.4 6.2 3e-12 46.3 6.2 1.7 1 0 0 1 1 1 1 Fungal cellulose binding domain Dfp1_Him1_M PF08630.10 KKK23692.1 - 2.8e-37 127.7 0.0 8.6e-37 126.2 0.0 1.9 1 0 0 1 1 1 1 Dfp1/Him1, central region zf-DBF PF07535.12 KKK23692.1 - 7.1e-21 74.0 0.2 1.3e-20 73.2 0.2 1.5 1 0 0 1 1 1 1 DBF zinc finger Pyridox_ox_2 PF12900.7 KKK23693.1 - 1.7e-38 131.8 0.0 2.3e-38 131.3 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Peptidase_M24 PF00557.24 KKK23694.1 - 2e-45 155.0 0.0 3.7e-45 154.2 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 KKK23694.1 - 2.7e-36 124.0 0.0 4.3e-36 123.4 0.0 1.3 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Creatinase_N PF01321.18 KKK23694.1 - 0.1 13.3 0.0 0.51 11.0 0.0 2.1 1 1 0 1 1 1 0 Creatinase/Prolidase N-terminal domain RuBisCO_large PF00016.20 KKK23694.1 - 0.16 11.2 0.0 0.24 10.5 0.0 1.2 1 0 0 1 1 1 0 Ribulose bisphosphate carboxylase large chain, catalytic domain 4HBT PF03061.22 KKK23695.1 - 7.3e-09 35.9 0.0 1.4e-08 35.0 0.0 1.5 1 0 0 1 1 1 1 Thioesterase superfamily SIR2 PF02146.17 KKK23696.1 - 6.6e-40 136.9 0.0 1.4e-39 135.8 0.0 1.5 1 1 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.22 KKK23696.1 - 0.011 15.5 0.0 0.13 12.0 0.0 2.2 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain Fungal_trans PF04082.18 KKK23703.1 - 4.8e-26 91.4 0.4 8.9e-26 90.5 0.4 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF2420 PF10336.9 KKK23705.1 - 7.8e-16 58.0 1.3 1.4e-15 57.3 1.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2420) Adap_comp_sub PF00928.21 KKK23706.1 - 1.3e-19 70.6 0.0 2.1e-19 70.0 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KKK23706.1 - 6.8e-06 26.1 0.1 1.2e-05 25.3 0.1 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.9 KKK23706.1 - 1.5e-05 24.6 0.0 3.7e-05 23.3 0.0 1.6 1 1 0 1 1 1 1 Muniscin C-terminal mu homology domain RPM2 PF08579.11 KKK23706.1 - 0.00094 19.6 0.4 0.0018 18.6 0.4 1.4 1 0 0 1 1 1 1 Mitochondrial ribonuclease P subunit (RPM2) TMF_DNA_bd PF12329.8 KKK23707.1 - 0.047 13.7 3.3 0.093 12.7 3.3 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Atg14 PF10186.9 KKK23707.1 - 2.3 7.2 5.1 0.62 9.1 1.8 1.6 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 OMPdecase PF00215.24 KKK23708.1 - 4.3e-10 39.6 0.0 3.1e-06 27.0 0.0 2.3 2 1 0 2 2 2 2 Orotidine 5'-phosphate decarboxylase / HUMPS family RRM_1 PF00076.22 KKK23709.1 - 1.1e-40 137.3 0.7 3e-19 68.6 0.1 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.6 KKK23709.1 - 1e-23 84.2 0.2 2.7e-23 82.8 0.2 1.8 1 0 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein Cyt-b5 PF00173.28 KKK23709.1 - 6.1e-18 64.7 0.1 6.1e-18 64.7 0.1 1.9 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.13 KKK23709.1 - 1.5e-12 48.0 19.3 1.8e-12 47.7 18.4 1.7 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily RRM_occluded PF16842.5 KKK23709.1 - 0.00029 20.6 0.0 0.37 10.7 0.0 3.0 3 0 0 3 3 3 2 Occluded RNA-recognition motif RRM_3 PF08777.11 KKK23709.1 - 0.025 14.6 0.0 0.11 12.6 0.0 2.0 1 0 0 1 1 1 0 RNA binding motif PHM7_cyt PF14703.6 KKK23709.1 - 0.056 13.7 0.1 5 7.3 0.1 2.9 1 1 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter Anth_synt_I_N PF04715.13 KKK23709.1 - 0.12 12.6 0.1 0.26 11.5 0.1 1.5 1 0 0 1 1 1 0 Anthranilate synthase component I, N terminal region RRM_7 PF16367.5 KKK23709.1 - 0.15 12.2 0.0 2.7 8.1 0.0 2.5 2 0 0 2 2 2 0 RNA recognition motif COX14 PF14880.6 KKK23709.1 - 0.17 11.8 1.1 0.36 10.7 0.2 2.0 2 0 0 2 2 2 0 Cytochrome oxidase c assembly Mg_trans_NIPA PF05653.14 KKK23710.1 - 2e-88 296.3 16.7 2.6e-85 286.1 12.7 2.0 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.20 KKK23710.1 - 8.7e-07 29.2 30.3 3.6e-06 27.2 1.9 3.2 3 0 0 3 3 3 3 EamA-like transporter family DUF2937 PF11157.8 KKK23710.1 - 0.099 12.3 0.6 0.27 10.9 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) CDC73_C PF05179.14 KKK23722.1 - 1.6e-55 187.1 0.0 2.6e-55 186.4 0.0 1.3 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family, C-terminal RGS PF00615.19 KKK23723.1 - 6.8e-20 71.5 0.0 7.9e-20 71.3 0.0 1.1 1 0 0 1 1 1 1 Regulator of G protein signaling domain STI1 PF17830.1 KKK23723.1 - 0.14 12.1 0.1 0.54 10.2 0.0 1.8 2 0 0 2 2 2 0 STI1 domain Glyco_hydro_61 PF03443.14 KKK23725.1 - 8.4e-64 215.3 0.0 1.1e-63 214.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 PHD PF00628.29 KKK23726.1 - 3.9e-05 23.5 9.7 7.6e-05 22.5 9.7 1.5 1 0 0 1 1 1 1 PHD-finger SET PF00856.28 KKK23726.1 - 5.8e-05 23.5 0.5 0.00039 20.8 0.5 2.5 1 1 0 1 1 1 1 SET domain RasGEF PF00617.19 KKK23733.1 - 0.00052 20.3 0.0 0.0017 18.6 0.0 1.9 2 1 0 2 2 2 1 RasGEF domain Adeno_E3_CR2 PF02439.15 KKK23740.1 - 0.32 10.8 1.0 0.59 9.9 1.0 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF1992 PF09350.10 KKK23741.1 - 2.4e-21 75.7 2.2 2.9e-21 75.4 0.3 2.2 2 1 1 3 3 3 1 Domain of unknown function (DUF1992) NPP1 PF05630.11 KKK23767.1 - 1.8e-61 207.7 0.0 2e-61 207.5 0.0 1.0 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) SurE PF01975.17 KKK23768.1 - 6e-33 114.3 1.0 7.8e-33 113.9 1.0 1.1 1 0 0 1 1 1 1 Survival protein SurE Glyco_hydro_61 PF03443.14 KKK23769.1 - 9.6e-69 231.4 0.3 9.6e-69 231.4 0.3 1.8 2 0 0 2 2 2 1 Glycosyl hydrolase family 61 CBM_1 PF00734.18 KKK23769.1 - 1.1e-11 44.5 4.8 2.9e-11 43.1 4.8 1.8 1 0 0 1 1 1 1 Fungal cellulose binding domain RPE65 PF03055.15 KKK23770.1 - 8.3e-103 345.0 0.0 1e-102 344.7 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein adh_short PF00106.25 KKK23797.1 - 1.5e-36 125.7 0.0 1.8e-36 125.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KKK23797.1 - 6.9e-23 81.4 0.0 8.6e-23 81.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KKK23797.1 - 1.5e-07 31.5 0.0 2e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KKK23797.1 - 0.00039 20.4 0.0 0.00053 19.9 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 KKK23797.1 - 0.00048 20.4 0.1 0.00076 19.7 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_2 PF03446.15 KKK23797.1 - 0.013 15.7 0.0 0.025 14.7 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.16 KKK23797.1 - 0.013 15.2 0.0 0.022 14.4 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA ADH_zinc_N PF00107.26 KKK23797.1 - 0.013 15.4 0.1 0.02 14.8 0.1 1.3 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Epimerase PF01370.21 KKK23797.1 - 0.024 14.1 0.2 0.064 12.7 0.2 1.8 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.17 KKK23797.1 - 0.031 14.8 0.0 0.075 13.6 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 KKK23797.1 - 0.032 14.3 0.0 0.058 13.5 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Syja_N PF02383.18 KKK23798.1 - 3.3e-91 305.9 0.0 4.3e-91 305.6 0.0 1.1 1 0 0 1 1 1 1 SacI homology domain cobW PF02492.19 KKK23801.1 - 8.5e-43 146.0 0.0 1.2e-42 145.5 0.0 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.14 KKK23801.1 - 0.0036 17.2 0.0 0.0036 17.2 0.0 2.0 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.6 KKK23801.1 - 0.0067 16.7 0.3 0.1 12.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain CobW_C PF07683.14 KKK23801.1 - 0.016 15.1 0.0 0.18 11.8 0.0 2.7 2 1 0 2 2 2 0 Cobalamin synthesis protein cobW C-terminal domain AAA_29 PF13555.6 KKK23801.1 - 0.028 14.2 0.1 0.47 10.2 0.0 2.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_16 PF13191.6 KKK23801.1 - 0.03 14.7 0.0 0.063 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.6 KKK23801.1 - 0.1 13.1 0.1 0.31 11.6 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KKK23801.1 - 0.14 12.2 0.0 0.3 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain SelP_N PF04592.14 KKK23801.1 - 0.14 11.6 11.1 0.25 10.7 11.1 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Orn_Arg_deC_N PF02784.16 KKK23802.1 - 9.3e-82 274.1 0.0 1.2e-81 273.8 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 KKK23802.1 - 3.1e-20 72.2 0.0 6.3e-20 71.2 0.0 1.6 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain AP_endonuc_2 PF01261.24 KKK23802.1 - 0.0063 16.0 0.0 0.024 14.1 0.0 1.8 2 0 0 2 2 2 1 Xylose isomerase-like TIM barrel Mitofilin PF09731.9 KKK23804.1 - 1.6e-163 545.9 24.3 1.8e-134 450.0 28.8 2.0 1 1 1 2 2 2 2 Mitochondrial inner membrane protein MobL PF18555.1 KKK23804.1 - 0.32 10.2 8.0 0.45 9.7 8.0 1.1 1 0 0 1 1 1 0 MobL relaxases Peptidase_C98 PF15499.6 KKK23804.1 - 2.2 7.7 5.4 5.3 6.4 0.1 2.2 1 1 1 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase Ras PF00071.22 KKK23805.1 - 2.4e-47 160.5 0.5 3.1e-47 160.2 0.5 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KKK23805.1 - 2e-25 89.3 0.4 5.4e-25 88.0 0.3 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKK23805.1 - 1.6e-10 40.7 0.1 1.9e-10 40.4 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KKK23805.1 - 6e-07 29.2 0.0 7.8e-07 28.8 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KKK23805.1 - 0.00016 21.2 0.0 0.00018 20.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 KKK23805.1 - 0.037 13.9 0.1 0.074 13.0 0.1 1.5 1 1 1 2 2 2 0 RsgA GTPase tRNA-synt_1g PF09334.11 KKK23806.1 - 1.2e-93 313.9 0.1 5.2e-92 308.6 0.1 2.3 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 KKK23806.1 - 1.3e-21 76.6 0.1 8.4e-10 37.5 0.0 3.4 2 2 2 4 4 4 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 KKK23806.1 - 1.5e-11 44.2 0.0 0.00016 21.2 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Anticodon_1 PF08264.13 KKK23806.1 - 0.0016 18.4 0.0 0.0032 17.5 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA HTH_AraC PF00165.23 KKK23806.1 - 0.0072 16.4 0.1 0.58 10.3 0.0 2.5 1 1 1 2 2 2 1 Bacterial regulatory helix-turn-helix proteins, AraC family NTF2 PF02136.20 KKK23807.1 - 5.8e-08 33.3 0.6 1.5e-07 32.0 0.6 1.6 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Mtr2 PF10429.9 KKK23807.1 - 0.00036 20.5 0.1 0.0013 18.7 0.1 1.7 2 0 0 2 2 2 1 Nuclear pore RNA shuttling protein Mtr2 PPTA PF01239.22 KKK23808.1 - 2.9e-32 109.4 22.2 3.7e-09 36.0 1.0 5.7 6 0 0 6 6 6 5 Protein prenyltransferase alpha subunit repeat TPR_14 PF13428.6 KKK23808.1 - 0.021 15.6 0.1 0.21 12.5 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF4269 PF14091.6 KKK23808.1 - 0.1 12.9 0.1 0.19 12.0 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4269) PALP PF00291.25 KKK23809.1 - 1.5e-49 169.0 0.7 3.5e-49 167.8 0.4 1.7 2 1 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme DUF3446 PF11928.8 KKK23809.1 - 0.034 14.4 9.7 0.04 14.2 2.3 2.7 2 0 0 2 2 2 0 Early growth response N-terminal domain Dehydrin PF00257.19 KKK23809.1 - 0.66 10.5 5.8 7.6 7.1 1.2 2.3 2 0 0 2 2 2 0 Dehydrin IMUP PF15761.5 KKK23809.1 - 1.5 9.6 11.7 0.36 11.5 1.8 2.5 2 0 0 2 2 2 0 Immortalisation up-regulated protein GHMP_kinases_N PF00288.26 KKK23810.1 - 7.3e-16 58.2 0.1 2.3e-15 56.5 0.1 1.9 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KKK23810.1 - 2.3e-07 31.1 0.0 6e-07 29.7 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.9 KKK23810.1 - 0.0035 16.9 0.1 0.0075 15.8 0.1 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature Fungal_trans_2 PF11951.8 KKK23811.1 - 4.8e-29 101.3 0.0 9.5e-18 64.2 0.0 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK23811.1 - 4.7e-09 36.2 7.9 8.2e-09 35.5 7.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Alpha-amylase PF00128.24 KKK23812.1 - 1.8e-22 80.4 0.0 3.3e-22 79.5 0.0 1.3 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_hydro_70 PF02324.16 KKK23812.1 - 1.6e-06 26.6 0.0 0.0048 15.2 0.0 3.0 3 0 0 3 3 3 3 Glycosyl hydrolase family 70 GPI-anchored PF10342.9 KKK23813.1 - 1.9e-21 76.6 1.6 1.9e-21 76.6 1.6 2.6 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family CCDC84 PF14968.6 KKK23813.1 - 0.19 11.3 5.2 0.24 11.0 5.2 1.1 1 0 0 1 1 1 0 Coiled coil protein 84 Mucin PF01456.17 KKK23813.1 - 0.4 10.7 34.4 0.13 12.3 31.3 1.7 2 0 0 2 2 2 0 Mucin-like glycoprotein Macoilin PF09726.9 KKK23813.1 - 0.58 8.7 12.0 0.62 8.5 12.0 1.1 1 0 0 1 1 1 0 Macoilin family SOG2 PF10428.9 KKK23813.1 - 1.3 8.2 19.1 1.3 8.1 19.1 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein GREB1 PF15782.5 KKK23813.1 - 5.8 3.9 8.8 6.3 3.8 8.8 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SWI-SNF_Ssr4 PF08549.10 KKK23813.1 - 8.9 4.8 8.7 11 4.6 8.7 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) Alpha-amylase PF00128.24 KKK23814.1 - 7.5e-18 65.2 0.2 3.7e-17 62.9 0.1 2.1 2 1 0 2 2 2 1 Alpha amylase, catalytic domain Glyco_transf_5 PF08323.11 KKK23814.1 - 1e-14 54.9 0.1 1.8e-14 54.0 0.1 1.3 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 KKK23814.1 - 5e-05 22.9 0.0 9.7e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KKK23814.1 - 0.018 15.0 0.0 0.046 13.7 0.0 1.6 1 0 0 1 1 1 0 Glycosyltransferase Family 4 Alpha-amylase PF00128.24 KKK23815.1 - 1.2e-47 163.1 1.9 1.6e-47 162.7 1.9 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.11 KKK23815.1 - 7e-30 103.2 0.0 1.7e-29 101.9 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) Glyco_hydro_61 PF03443.14 KKK23816.1 - 1.8e-68 230.6 0.2 2.2e-68 230.3 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 NARG2_C PF10505.9 KKK23816.1 - 0.17 11.4 0.0 0.21 11.1 0.0 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated gene protein 2 C-terminus Ribosomal_L38e PF01781.18 KKK23817.1 - 6.5e-32 109.4 2.2 7.9e-32 109.2 2.2 1.1 1 0 0 1 1 1 1 Ribosomal L38e protein family NMO PF03060.15 KKK23818.1 - 3.5e-54 184.4 0.5 5.1e-54 183.9 0.5 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 KKK23818.1 - 3e-09 36.3 1.5 3e-09 36.3 1.5 1.5 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 KKK23818.1 - 0.00029 20.0 3.1 0.00054 19.1 3.1 1.4 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 KKK23818.1 - 0.19 10.8 0.8 0.33 10.0 0.8 1.3 1 0 0 1 1 1 0 Conserved region in glutamate synthase DNA_pol_E_B PF04042.16 KKK23819.1 - 1.4e-46 158.5 0.0 2e-46 158.0 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DNA_pol_D_N PF18018.1 KKK23819.1 - 4.9e-40 136.6 0.0 7e-40 136.1 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain Acetyltransf_3 PF13302.7 KKK23820.1 - 1.1e-19 71.5 0.0 1.4e-19 71.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 KKK23820.1 - 0.00036 20.2 0.3 0.0047 16.6 0.2 2.5 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KKK23820.1 - 0.041 13.8 0.1 5.8 6.9 0.0 2.3 2 0 0 2 2 2 0 FR47-like protein Methyltransf_16 PF10294.9 KKK23821.1 - 1e-57 194.7 0.0 1.7e-57 193.9 0.0 1.4 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_31 PF13847.6 KKK23821.1 - 0.0013 18.5 0.0 0.0021 17.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKK23821.1 - 0.018 15.7 0.0 0.039 14.7 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 KKK23821.1 - 0.15 12.9 0.0 0.28 12.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain M16C_assoc PF08367.11 KKK23823.1 - 3.2e-71 239.4 0.0 4.5e-71 238.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.21 KKK23823.1 - 2.6e-18 66.7 0.0 2.1e-11 44.2 0.0 2.7 3 0 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 KKK23823.1 - 2.8e-10 40.3 0.0 1.9e-09 37.7 0.0 2.2 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Taxilin PF09728.9 KKK23824.1 - 4e-93 312.0 52.6 4e-93 312.0 52.6 1.6 2 0 0 2 2 2 1 Myosin-like coiled-coil protein GOLGA2L5 PF15070.6 KKK23824.1 - 0.77 8.3 45.3 0.26 9.9 34.3 2.1 1 1 1 2 2 2 0 Putative golgin subfamily A member 2-like protein 5 DUF3675 PF12428.8 KKK23824.1 - 1 9.9 2.4 13 6.4 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3675) DUF4201 PF13870.6 KKK23824.1 - 7.8 6.2 55.7 0.017 14.9 14.6 4.4 1 1 3 5 5 5 0 Domain of unknown function (DUF4201) AA_permease PF00324.21 KKK23825.1 - 2.4e-99 333.1 37.5 3e-99 332.8 37.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KKK23825.1 - 2.6e-23 82.5 39.6 3.6e-23 82.1 39.6 1.1 1 0 0 1 1 1 1 Amino acid permease MgtE PF01769.16 KKK23825.1 - 0.036 14.4 1.6 0.036 14.4 1.6 4.3 3 1 0 3 3 3 0 Divalent cation transporter ADH_zinc_N PF00107.26 KKK23826.1 - 9.8e-25 87.0 0.2 1.6e-24 86.3 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KKK23826.1 - 2.4e-16 61.0 0.0 5.3e-16 59.9 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KKK23826.1 - 2.6e-11 43.3 0.0 1e-10 41.5 0.0 2.0 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.18 KKK23826.1 - 0.0014 18.9 0.0 0.0024 18.1 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain ADH_N_2 PF16884.5 KKK23826.1 - 0.0048 16.8 0.0 0.0088 15.9 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase AlaDh_PNT_C PF01262.21 KKK23826.1 - 0.0063 15.8 0.0 0.012 14.9 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 KKK23826.1 - 0.052 12.9 0.0 0.078 12.3 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ELFV_dehydrog PF00208.21 KKK23826.1 - 0.064 13.0 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Raffinose_syn PF05691.12 KKK23827.1 - 3.7e-50 170.5 0.7 9.2e-48 162.6 0.4 2.4 2 1 0 2 2 2 1 Raffinose synthase or seed imbibition protein Sip1 HAD_2 PF13419.6 KKK23830.1 - 1.1e-12 48.4 0.0 1.8e-12 47.7 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KKK23830.1 - 5.1e-05 23.7 0.0 0.00014 22.2 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KKK23830.1 - 8.8e-05 22.5 0.0 0.00088 19.3 0.0 2.3 1 1 0 1 1 1 1 HAD-hyrolase-like EBP PF05241.12 KKK23831.1 - 1.5e-65 219.9 8.8 1.8e-65 219.7 8.8 1.0 1 0 0 1 1 1 1 Emopamil binding protein TPR_1 PF00515.28 KKK23833.1 - 0.00053 19.7 6.9 0.095 12.6 0.0 4.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 KKK23833.1 - 0.00065 19.9 0.3 0.0019 18.4 0.3 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.6 KKK23833.1 - 0.023 14.7 0.1 4.9 7.4 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 KKK23833.1 - 0.035 14.2 5.2 5.4 7.4 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.6 KKK23833.1 - 0.12 12.8 0.4 0.56 10.7 0.2 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 KKK23833.1 - 0.14 11.9 0.7 0.41 10.4 0.7 1.9 1 0 0 1 1 1 0 TPR repeat TPR_19 PF14559.6 KKK23833.1 - 0.19 12.3 0.4 0.19 12.3 0.4 2.5 2 1 0 2 2 2 0 Tetratricopeptide repeat T6SS_VasJ PF16989.5 KKK23833.1 - 2.3 7.6 8.1 1.6 8.2 0.1 2.9 2 1 1 3 3 3 0 Type VI secretion, EvfE, EvfF, ImpA, BimE, VC_A0119, VasJ TPR_6 PF13174.6 KKK23833.1 - 4.6 8.1 5.2 25 5.8 0.0 3.4 3 1 0 3 3 3 0 Tetratricopeptide repeat MFS_1 PF07690.16 KKK23834.1 - 5e-16 58.6 11.4 4.1e-10 39.1 0.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KKK23834.1 - 0.024 13.2 1.1 0.032 12.8 1.1 1.2 1 0 0 1 1 1 0 MFS/sugar transport protein DUF1700 PF08006.11 KKK23834.1 - 0.076 12.6 0.4 7 6.1 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1700) HKR_ArcB_TM PF18415.1 KKK23834.1 - 0.84 10.5 3.7 0.79 10.6 0.1 2.2 2 0 0 2 2 2 0 Histidine kinase receptor ArcB trans-membrane domain NAD_binding_1 PF00175.21 KKK23835.1 - 2e-15 57.4 0.0 3.2e-15 56.7 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KKK23835.1 - 3.2e-14 53.1 0.0 5.3e-14 52.4 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain PI31_Prot_N PF11566.8 KKK23836.1 - 2.9e-51 173.5 0.0 3.6e-51 173.2 0.0 1.1 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.11 KKK23836.1 - 2.1e-17 64.0 17.2 2.1e-17 64.0 17.2 3.2 3 1 0 3 3 3 1 PI31 proteasome regulator Metallophos PF00149.28 KKK23837.1 - 5.7e-38 131.5 0.4 9.7e-38 130.7 0.4 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KKK23837.1 - 0.023 15.1 0.1 0.048 14.1 0.1 1.5 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain CBM-like PF14683.6 KKK23838.1 - 8.1e-27 94.1 0.1 3e-26 92.3 0.0 2.1 3 0 0 3 3 3 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.6 KKK23838.1 - 1.9e-22 78.8 0.7 5.5e-22 77.3 0.7 1.9 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain II CarboxypepD_reg PF13620.6 KKK23838.1 - 0.0027 17.9 0.3 0.012 15.9 0.3 2.1 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain DUF2012 PF09430.10 KKK23838.1 - 0.05 13.7 0.1 0.33 11.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2012) CarbopepD_reg_2 PF13715.6 KKK23838.1 - 0.076 13.0 0.3 6.2 6.9 0.0 2.6 2 0 0 2 2 2 0 CarboxypepD_reg-like domain Acyl-CoA_dh_1 PF00441.24 KKK23839.1 - 2.2e-22 79.9 0.4 1.1e-21 77.6 0.4 2.0 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cyt-b5 PF00173.28 KKK23839.1 - 3.3e-20 72.0 0.0 7.1e-20 70.9 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_M PF02770.19 KKK23839.1 - 7.6e-19 67.7 0.2 1.3e-18 66.9 0.2 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 KKK23839.1 - 1.9e-06 28.5 0.3 7.3e-06 26.6 0.0 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Ferric_reduct PF01794.19 KKK23840.1 - 1.8e-24 86.2 13.9 1.8e-24 86.2 13.9 1.8 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KKK23840.1 - 1.4e-15 57.8 0.0 2.1e-15 57.2 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KKK23840.1 - 3.8e-09 36.6 0.0 0.0063 16.6 0.0 2.9 3 0 0 3 3 3 2 FAD-binding domain NAD_binding_1 PF00175.21 KKK23840.1 - 0.001 19.7 0.0 0.0071 17.0 0.0 2.1 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain TFCD_C PF12612.8 KKK23889.1 - 1.2e-28 100.2 0.1 4.5e-28 98.4 0.1 2.1 2 0 0 2 2 2 1 Tubulin folding cofactor D C terminal HEAT_2 PF13646.6 KKK23889.1 - 1.2e-05 25.6 4.7 0.07 13.5 0.1 5.1 5 0 0 5 5 5 2 HEAT repeats HEAT PF02985.22 KKK23889.1 - 1.5e-05 24.8 6.8 0.15 12.4 0.0 6.4 6 0 0 6 6 6 1 HEAT repeat IFRD PF05004.13 KKK23889.1 - 0.0026 16.9 0.3 0.0081 15.3 0.3 1.8 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) Arm PF00514.23 KKK23889.1 - 0.031 14.3 0.1 1.5 9.0 0.0 3.2 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat HEAT_PBS PF03130.16 KKK23889.1 - 0.061 14.0 0.3 63 4.7 0.1 4.4 3 0 0 3 3 3 0 PBS lyase HEAT-like repeat Vac14_Fab1_bd PF12755.7 KKK23889.1 - 0.062 13.9 0.0 0.58 10.8 0.0 2.7 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 KKK23889.1 - 0.26 11.8 5.6 5.2 7.7 0.0 4.9 5 0 0 5 5 5 0 HEAT-like repeat HR1 PF02185.16 KKK23892.1 - 3.8e-28 97.4 19.9 1.6e-15 57.0 4.5 2.7 3 0 0 3 3 3 2 Hr1 repeat C1_1 PF00130.22 KKK23892.1 - 4.7e-21 74.4 28.6 2.6e-12 46.4 9.2 2.2 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) C2 PF00168.30 KKK23892.1 - 2.3e-05 24.6 0.0 5.1e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 C2 domain DUF4726 PF15855.5 KKK23892.1 - 0.048 13.9 0.6 0.048 13.9 0.6 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4726) zf-RING_9 PF13901.6 KKK23892.1 - 0.66 9.9 21.5 0.54 10.2 7.2 2.3 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon Uds1 PF15456.6 KKK23892.1 - 1.4 9.0 6.3 0.7 10.1 0.9 2.5 2 0 0 2 2 2 0 Up-regulated During Septation SNARE PF05739.19 KKK23893.1 - 1.6e-12 47.2 0.5 4.1e-12 45.9 0.1 2.0 2 0 0 2 2 2 1 SNARE domain Syntaxin-5_N PF11416.8 KKK23893.1 - 2.8e-10 39.1 0.0 5.9e-10 38.1 0.0 1.6 1 0 0 1 1 1 1 Syntaxin-5 N-terminal, Sly1p-binding domain KxDL PF10241.9 KKK23893.1 - 4.4e-05 23.7 0.5 0.16 12.3 0.1 2.9 2 0 0 2 2 2 2 Uncharacterized conserved protein Syntaxin PF00804.25 KKK23893.1 - 0.00076 19.2 2.9 0.0088 15.7 0.1 2.6 2 1 0 2 2 2 1 Syntaxin DUF4988 PF16378.5 KKK23893.1 - 0.019 14.6 1.4 11 5.6 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function Snapin_Pallidin PF14712.6 KKK23893.1 - 0.042 14.3 0.1 10 6.6 0.0 2.8 2 0 0 2 2 2 0 Snapin/Pallidin NPV_P10 PF05531.12 KKK23893.1 - 0.31 11.5 4.8 22 5.6 0.2 3.3 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein MCPsignal PF00015.21 KKK23893.1 - 0.36 10.6 6.6 0.49 10.2 1.1 2.6 2 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain SlyX PF04102.12 KKK23893.1 - 0.45 11.2 4.0 1.3 9.7 0.2 2.9 2 1 0 2 2 2 0 SlyX Peptidase_M50B PF13398.6 KKK23894.1 - 1.2e-59 201.3 22.7 1.5e-59 201.0 22.7 1.1 1 0 0 1 1 1 1 Peptidase M50B-like Peptidase_M50 PF02163.22 KKK23894.1 - 0.0084 15.4 0.4 0.017 14.4 0.4 1.5 1 0 0 1 1 1 1 Peptidase family M50 YlaC PF10777.9 KKK23894.1 - 3.8 7.3 6.9 0.23 11.3 0.5 2.1 2 0 0 2 2 2 0 Inner membrane protein YlaC Patched PF02460.18 KKK23894.1 - 4.9 5.1 6.9 7.6 4.5 6.9 1.2 1 0 0 1 1 1 0 Patched family DUF1275 PF06912.11 KKK23895.1 - 9.5e-44 149.6 10.7 1.2e-43 149.3 10.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) SUR7 PF06687.12 KKK23896.1 - 2e-27 96.2 9.1 2.8e-27 95.8 9.1 1.1 1 0 0 1 1 1 1 SUR7/PalI family SCIMP PF15050.6 KKK23896.1 - 0.012 16.1 0.0 0.05 14.1 0.0 2.1 2 0 0 2 2 2 0 SCIMP protein DUF4381 PF14316.6 KKK23896.1 - 1.6 9.0 4.2 0.42 10.8 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) Aminotran_1_2 PF00155.21 KKK23898.1 - 5.5e-59 200.2 0.0 6.7e-59 199.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KKK23898.1 - 0.011 14.3 0.0 0.017 13.7 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Alliinase_C PF04864.13 KKK23898.1 - 0.058 12.2 0.0 0.084 11.7 0.0 1.1 1 0 0 1 1 1 0 Allinase Glyco_hydro_3 PF00933.21 KKK23899.1 - 1.6e-56 192.0 0.0 2.7e-56 191.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 KKK23899.1 - 1.9e-56 191.3 0.4 7.2e-55 186.1 0.0 2.5 3 0 0 3 3 3 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 KKK23899.1 - 1.2e-22 79.8 0.4 4.7e-22 77.9 0.2 2.1 2 0 0 2 2 2 1 Fibronectin type III-like domain PA14 PF07691.12 KKK23899.1 - 0.002 18.0 0.0 0.0042 16.9 0.0 1.6 1 0 0 1 1 1 1 PA14 domain CARDB PF07705.11 KKK23899.1 - 0.077 13.3 0.2 0.33 11.2 0.1 2.1 2 0 0 2 2 2 0 CARDB DHHC PF01529.20 KKK23900.1 - 0.29 11.3 3.9 1.5 8.9 0.5 2.7 2 1 1 3 3 3 0 DHHC palmitoyltransferase PH PF00169.29 KKK23948.1 - 0.11 13.0 0.0 0.69 10.5 0.0 2.3 2 1 0 2 2 2 0 PH domain Sec62 PF03839.16 KKK23949.1 - 6.3e-76 254.7 0.6 6.3e-76 254.7 0.6 1.8 2 0 0 2 2 2 1 Translocation protein Sec62 BTRD1 PF17660.1 KKK23949.1 - 0.01 15.7 0.4 2.1 8.2 0.1 2.5 1 1 1 2 2 2 0 Bacterial tandem repeat domain 1 TFIIA PF03153.13 KKK23949.1 - 2.9 7.8 22.7 4.8 7.1 22.7 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit p450 PF00067.22 KKK23950.1 - 1.8e-05 23.7 0.0 2.2e-05 23.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 LEH PF07858.12 KKK23950.1 - 0.039 14.1 0.0 0.06 13.4 0.0 1.3 1 0 0 1 1 1 0 Limonene-1,2-epoxide hydrolase catalytic domain RHSP PF07999.11 KKK23950.1 - 0.041 12.7 0.0 0.051 12.4 0.0 1.1 1 0 0 1 1 1 0 Retrotransposon hot spot protein DUF726 PF05277.12 KKK23951.1 - 3.4e-119 397.8 0.5 4.4e-119 397.4 0.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) CPP1-like PF11833.8 KKK23951.1 - 0.054 13.1 0.0 0.15 11.7 0.0 1.8 1 0 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like SNAP PF14938.6 KKK23952.1 - 1.9e-114 381.8 14.6 2.2e-114 381.7 14.6 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.6 KKK23952.1 - 1.1e-07 32.0 14.5 0.00096 19.4 0.3 4.1 3 2 0 3 3 3 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KKK23952.1 - 3.9e-05 23.2 5.4 0.00013 21.5 1.6 2.2 1 1 1 2 2 2 1 MalT-like TPR region TPR_7 PF13176.6 KKK23952.1 - 4.4e-05 23.2 7.9 4.1 7.7 0.2 4.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_6 PF13174.6 KKK23952.1 - 0.00016 22.1 13.9 1.4 9.7 0.1 6.2 6 1 0 6 6 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 KKK23952.1 - 0.0011 19.0 12.5 0.59 10.5 0.3 4.8 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 KKK23952.1 - 0.0032 17.4 22.4 3.7 7.9 2.0 6.7 4 2 4 8 8 8 3 Tetratricopeptide repeat TPR_1 PF00515.28 KKK23952.1 - 0.011 15.5 20.4 0.75 9.7 0.8 5.8 5 2 2 7 7 7 0 Tetratricopeptide repeat TPR_14 PF13428.6 KKK23952.1 - 0.016 15.9 15.1 14 6.8 0.7 5.9 2 1 4 6 6 6 0 Tetratricopeptide repeat NSF PF02071.20 KKK23952.1 - 0.33 11.9 20.5 1.3 10.1 0.8 7.0 8 0 0 8 8 7 0 Aromatic-di-Alanine (AdAR) repeat FRB_dom PF08771.11 KKK23952.1 - 0.76 10.2 4.7 0.28 11.6 0.5 2.4 3 1 0 3 3 3 0 FKBP12-rapamycin binding domain MIT PF04212.18 KKK23952.1 - 7.7 6.7 16.6 4 7.6 1.1 4.5 1 1 3 4 4 4 0 MIT (microtubule interacting and transport) domain Glu-tRNAGln PF02686.15 KKK23953.1 - 8.1e-13 48.5 0.1 7.4e-12 45.4 0.1 2.2 1 1 0 1 1 1 1 Glu-tRNAGln amidotransferase C subunit BING4CT PF08149.11 KKK23954.1 - 1.9e-37 126.9 0.0 3e-35 119.9 0.0 2.8 2 0 0 2 2 2 2 BING4CT (NUC141) domain ANAPC4_WD40 PF12894.7 KKK23954.1 - 2.9e-08 33.9 0.2 1.9 8.8 0.0 5.8 3 2 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KKK23954.1 - 0.0013 19.5 0.3 9.6 7.3 0.0 4.6 5 0 0 5 5 5 1 WD domain, G-beta repeat Coatomer_WDAD PF04053.14 KKK23954.1 - 0.0063 15.6 0.0 0.011 14.8 0.0 1.3 1 0 0 1 1 1 1 Coatomer WD associated region RIBIOP_C PF04950.12 KKK23955.1 - 2.4e-109 365.3 0.0 4.4e-109 364.4 0.0 1.4 1 0 0 1 1 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 KKK23955.1 - 1.6e-21 76.2 0.0 4e-21 74.9 0.0 1.7 1 0 0 1 1 1 1 AARP2CN (NUC121) domain MFS_1 PF07690.16 KKK23956.1 - 1.6e-24 86.5 26.3 2.7e-24 85.8 25.6 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF2046 PF09755.9 KKK23957.1 - 0.0024 17.2 1.0 0.0024 17.2 1.0 2.0 2 0 0 2 2 2 1 Uncharacterized conserved protein H4 (DUF2046) DUF3287 PF11690.8 KKK23957.1 - 0.0062 16.3 2.1 2.1 8.1 0.1 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF3287) Shugoshin_N PF07558.11 KKK23957.1 - 0.012 15.5 0.1 0.024 14.5 0.1 1.5 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region HOOK PF05622.12 KKK23957.1 - 0.016 13.4 5.5 0.043 12.0 0.3 2.0 2 0 0 2 2 2 0 HOOK protein PspA_IM30 PF04012.12 KKK23957.1 - 0.035 13.7 7.1 0.79 9.3 0.3 2.1 2 0 0 2 2 2 0 PspA/IM30 family SKA2 PF16740.5 KKK23957.1 - 0.074 12.8 7.5 0.73 9.6 6.1 2.1 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 DivIC PF04977.15 KKK23957.1 - 0.084 12.7 0.3 0.084 12.7 0.3 2.4 2 0 0 2 2 2 0 Septum formation initiator DUF16 PF01519.16 KKK23957.1 - 0.34 11.4 6.9 9.3 6.8 3.8 2.2 2 0 0 2 2 2 0 Protein of unknown function DUF16 FlaC_arch PF05377.11 KKK23957.1 - 0.8 10.2 3.0 2.2 8.8 0.0 2.3 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF2968 PF11180.8 KKK23957.1 - 3.9 7.1 17.8 0.19 11.3 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) Carn_acyltransf PF00755.20 KKK23958.1 - 1.1e-205 684.7 0.0 1.3e-205 684.5 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Rxt3 PF08642.10 KKK23959.1 - 4.7e-43 147.0 0.0 1.4e-42 145.5 0.0 1.9 1 0 0 1 1 1 1 Histone deacetylation protein Rxt3 LCCL PF03815.19 KKK23959.1 - 0.0018 18.3 0.0 0.007 16.5 0.0 1.9 1 0 0 1 1 1 1 LCCL domain LIM_bind PF01803.16 KKK23960.1 - 5e-70 235.8 0.7 5e-70 235.8 0.7 4.7 3 1 1 4 4 4 1 LIM-domain binding protein Pyr_redox_2 PF07992.14 KKK23961.1 - 3e-08 33.3 0.0 2.6e-07 30.2 0.0 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KKK23961.1 - 0.00042 20.5 0.0 0.0012 19.0 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 KKK23961.1 - 0.025 13.8 0.0 0.045 13.0 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.6 KKK23961.1 - 0.028 14.4 0.0 0.11 12.5 0.0 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding HI0933_like PF03486.14 KKK23961.1 - 0.072 11.8 0.0 0.12 11.0 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein Cerato-platanin PF07249.12 KKK23962.1 - 2.6e-51 172.7 0.3 3.1e-51 172.5 0.3 1.0 1 0 0 1 1 1 1 Cerato-platanin MF_alpha_N PF05436.11 KKK23962.1 - 0.0051 16.7 0.2 0.0084 16.0 0.2 1.4 1 0 0 1 1 1 1 Mating factor alpha precursor N-terminus Lectin_C PF00059.21 KKK23963.1 - 0.0025 18.5 0.7 0.0055 17.4 0.7 1.6 1 0 0 1 1 1 1 Lectin C-type domain Pkinase PF00069.25 KKK23964.1 - 4.8e-19 68.8 0.0 2.2e-18 66.6 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK23964.1 - 6.7e-07 28.9 0.0 2.1e-05 23.9 0.0 2.7 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KKK23964.1 - 0.00044 20.2 0.1 0.0012 18.8 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family RMF PF04957.12 KKK23964.1 - 0.068 13.4 0.1 0.14 12.4 0.1 1.5 1 0 0 1 1 1 0 Ribosome modulation factor RIO1 PF01163.22 KKK23964.1 - 0.15 11.7 0.1 0.5 9.9 0.0 1.7 2 0 0 2 2 2 0 RIO1 family Pterin_4a PF01329.19 KKK23965.1 - 0.00023 21.3 0.1 0.67 10.2 0.1 2.5 2 0 0 2 2 2 2 Pterin 4 alpha carbinolamine dehydratase Peptidase_C2 PF00648.21 KKK23966.1 - 2e-29 102.6 0.0 4.7e-29 101.4 0.0 1.6 1 1 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 KKK23966.1 - 4.6e-08 33.4 0.0 4.7e-05 23.7 0.0 3.7 3 1 0 3 3 3 1 Calpain large subunit, domain III MIT PF04212.18 KKK23966.1 - 0.00056 19.9 1.0 0.00095 19.2 1.0 1.3 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain Mito_carr PF00153.27 KKK23967.1 - 4.8e-55 183.5 1.5 1.1e-20 73.3 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein SNase PF00565.17 KKK23968.1 - 2.2e-18 66.7 0.7 2.5e-18 66.5 0.0 1.5 2 0 0 2 2 2 1 Staphylococcal nuclease homologue BSMAP PF12280.8 KKK23968.1 - 0.022 15.0 0.1 0.036 14.3 0.1 1.2 1 0 0 1 1 1 0 Brain specific membrane anchored protein ADK PF00406.22 KKK23969.1 - 8.7e-35 120.1 0.0 2.1e-34 118.8 0.0 1.5 1 1 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.14 KKK23969.1 - 3.6e-15 55.6 0.0 6e-15 54.9 0.0 1.4 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_17 PF13207.6 KKK23969.1 - 3.4e-13 50.2 0.0 1.3e-12 48.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KKK23969.1 - 1.7e-05 25.4 0.0 3.6e-05 24.3 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KKK23969.1 - 0.01 16.0 0.0 0.029 14.5 0.0 1.8 2 1 0 2 2 2 0 AAA domain MeaB PF03308.16 KKK23969.1 - 0.096 11.6 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_22 PF13401.6 KKK23969.1 - 0.15 12.4 0.0 0.25 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KKK23969.1 - 0.17 12.1 0.0 0.32 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain DNA_primase_lrg PF04104.14 KKK23970.1 - 1e-86 290.6 0.0 1.5e-86 290.1 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit Sec23_trunk PF04811.15 KKK23971.1 - 1.2e-80 270.6 0.0 1.9e-80 269.9 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 KKK23971.1 - 9.4e-30 103.2 0.1 2e-29 102.1 0.1 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 KKK23971.1 - 6.4e-25 87.0 0.1 1.9e-24 85.4 0.1 1.9 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Ribosomal_L11_N PF03946.14 KKK23971.1 - 6.4e-23 80.4 0.1 6.4e-23 80.4 0.1 1.9 2 0 0 2 2 2 1 Ribosomal protein L11, N-terminal domain zf-Sec23_Sec24 PF04810.15 KKK23971.1 - 8.5e-15 54.5 4.0 1.6e-14 53.6 4.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Ribosomal_L11 PF00298.19 KKK23971.1 - 4.7e-14 52.7 0.2 8.5e-14 51.8 0.2 1.5 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Gelsolin PF00626.22 KKK23971.1 - 5.8e-12 45.3 0.0 1.6e-11 43.9 0.0 1.8 2 0 0 2 2 2 1 Gelsolin repeat Vps36-NZF-N PF16988.5 KKK23971.1 - 0.0081 15.5 0.3 0.024 14.0 0.2 1.9 2 0 0 2 2 2 1 Vacuolar protein sorting 36 NZF-N zinc-finger domain Vta1 PF04652.16 KKK23972.1 - 7.2e-48 162.3 0.1 2e-47 160.8 0.1 1.7 1 1 0 1 1 1 1 Vta1 like Vta1_C PF18097.1 KKK23972.1 - 1.2e-15 56.9 0.2 2.4e-15 55.9 0.2 1.5 1 0 0 1 1 1 1 Vta1 C-terminal domain MSA_2 PF00985.17 KKK23972.1 - 0.043 14.2 1.7 0.043 14.2 1.7 2.3 2 1 2 4 4 4 0 Merozoite Surface Antigen 2 (MSA-2) family Dioxygenase_N PF04444.14 KKK23973.1 - 0.11 12.4 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Catechol dioxygenase N terminus Epimerase PF01370.21 KKK23974.1 - 5.8e-17 62.0 0.0 8.7e-17 61.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KKK23974.1 - 1.7e-08 33.8 0.0 2e-07 30.3 0.0 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KKK23974.1 - 7.8e-05 22.2 0.0 0.00057 19.4 0.0 2.0 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase Ldh_1_N PF00056.23 KKK23974.1 - 0.027 14.6 0.0 0.055 13.6 0.0 1.5 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain KR PF08659.10 KKK23974.1 - 0.074 13.0 0.0 0.27 11.1 0.0 1.9 2 1 0 2 2 2 0 KR domain BRO1 PF03097.18 KKK24004.1 - 2.6e-08 33.1 0.2 3.6e-08 32.6 0.2 1.3 1 0 0 1 1 1 1 BRO1-like domain ECH_1 PF00378.20 KKK24005.1 - 2.5e-21 76.2 0.0 3.1e-21 75.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KKK24005.1 - 0.0059 16.2 0.0 0.011 15.3 0.0 1.4 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Bromo_TP PF07524.13 KKK24007.1 - 2.9e-09 36.8 0.0 5.4e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated TFIID-31kDa PF02291.15 KKK24007.1 - 0.0097 16.0 0.0 0.015 15.3 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit TAFII55_N PF04658.13 KKK24008.1 - 5.3e-52 175.8 0.0 1.6e-51 174.2 0.0 1.8 2 0 0 2 2 2 1 TAFII55 protein conserved region YqjK PF13997.6 KKK24008.1 - 0.31 11.3 1.8 0.77 10.0 1.8 1.6 1 0 0 1 1 1 0 YqjK-like protein MnmE_helical PF12631.7 KKK24008.1 - 0.74 9.9 4.3 0.29 11.3 0.3 2.2 1 1 1 2 2 2 0 MnmE helical domain TPR_10 PF13374.6 KKK24026.1 - 1.4e-17 62.9 0.1 3.9e-06 26.6 0.0 3.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 KKK24026.1 - 7.4e-16 58.2 0.0 2e-12 47.2 0.0 2.8 2 1 1 3 3 2 2 Tetratricopeptide repeat PNP_UDP_1 PF01048.20 KKK24026.1 - 1.1e-12 47.8 0.3 6.4e-12 45.2 0.3 2.1 1 1 0 1 1 1 1 Phosphorylase superfamily NB-ARC PF00931.22 KKK24026.1 - 2.2e-12 46.7 0.0 3.6e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.6 KKK24026.1 - 1.1e-08 35.7 0.2 4.1e-07 30.5 0.2 2.5 1 1 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 KKK24026.1 - 3.2e-07 30.4 0.0 7.1e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 NACHT domain TPR_7 PF13176.6 KKK24026.1 - 2.1e-06 27.4 0.0 0.061 13.4 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat AAA_22 PF13401.6 KKK24026.1 - 0.00064 20.0 0.0 0.0017 18.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain TPR_2 PF07719.17 KKK24026.1 - 0.0052 16.8 0.1 3 8.2 0.0 3.6 4 0 0 4 4 3 1 Tetratricopeptide repeat ATPase_2 PF01637.18 KKK24026.1 - 0.006 16.5 0.0 0.012 15.5 0.0 1.5 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_14 PF13173.6 KKK24026.1 - 0.0079 16.2 0.0 0.023 14.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain TPR_1 PF00515.28 KKK24026.1 - 0.0093 15.8 0.0 1.6 8.7 0.0 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 KKK24026.1 - 0.025 14.8 0.1 59 4.3 0.0 4.1 4 0 0 4 4 3 0 Tetratricopeptide repeat ResIII PF04851.15 KKK24026.1 - 0.033 14.2 0.0 0.071 13.1 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit TPR_6 PF13174.6 KKK24026.1 - 0.037 14.7 0.0 2.7 8.8 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_MalT PF17874.1 KKK24026.1 - 0.05 13.0 0.0 0.2 11.0 0.0 2.0 2 0 0 2 2 2 0 MalT-like TPR region AAA PF00004.29 KKK24026.1 - 0.091 13.2 0.0 0.37 11.2 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) SRP54 PF00448.22 KKK24026.1 - 0.14 11.8 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain CHZ PF09649.10 KKK24027.1 - 2.9e-17 61.8 1.1 2.9e-17 61.8 1.1 2.5 2 0 0 2 2 2 1 Histone chaperone domain CHZ HSP70 PF00012.20 KKK24028.1 - 6.1e-262 870.1 8.2 7e-262 870.0 8.2 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KKK24028.1 - 1.5e-18 66.7 0.0 1.7e-17 63.2 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 KKK24028.1 - 0.001 18.8 0.0 0.0038 17.0 0.0 1.9 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 KKK24028.1 - 0.0064 16.9 6.1 4.7 7.7 0.2 3.7 3 2 0 3 3 3 2 Cell division protein FtsA Hydantoinase_A PF01968.18 KKK24028.1 - 0.026 13.8 0.1 0.06 12.6 0.1 1.6 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase BcrAD_BadFG PF01869.20 KKK24028.1 - 0.04 13.4 0.1 1.3 8.4 0.0 2.4 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family StbA PF06406.11 KKK24028.1 - 0.044 13.0 0.0 0.085 12.1 0.0 1.4 1 0 0 1 1 1 0 StbA protein Radial_spoke_3 PF06098.11 KKK24028.1 - 0.17 11.2 3.6 0.31 10.3 3.6 1.3 1 0 0 1 1 1 0 Radial spoke protein 3 Ribosomal_60s PF00428.19 KKK24028.1 - 9.9 6.8 8.6 16 6.2 4.5 3.2 3 0 0 3 3 3 0 60s Acidic ribosomal protein Mcl1_mid PF12341.8 KKK24029.1 - 1.5e-102 342.9 0.0 4.3e-102 341.4 0.0 1.8 2 0 0 2 2 2 1 Minichromosome loss protein, Mcl1, middle region WD40 PF00400.32 KKK24029.1 - 1.2e-18 67.1 0.4 1.2e-06 29.1 0.1 7.2 9 0 0 9 9 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKK24029.1 - 6.6e-17 61.6 0.0 3.1e-05 24.2 0.1 6.9 3 1 4 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 KKK24029.1 - 2.7e-07 30.0 0.0 6.5e-06 25.5 0.0 2.2 1 1 1 2 2 2 1 Coatomer WD associated region eIF2A PF08662.11 KKK24029.1 - 0.00013 21.9 0.1 0.012 15.5 0.0 3.0 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 KKK24029.1 - 0.0015 18.4 0.1 3.2 7.8 0.0 4.4 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KKK24029.1 - 0.0095 14.9 0.1 5.7 5.8 0.0 3.1 2 2 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein MMS1_N PF10433.9 KKK24029.1 - 0.01 14.5 0.0 0.1 11.2 0.0 2.4 3 0 0 3 3 3 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term Lactonase PF10282.9 KKK24029.1 - 0.021 14.1 0.0 0.5 9.6 0.0 2.3 1 1 1 2 2 2 0 Lactonase, 7-bladed beta-propeller DNA_pol_alpha_N PF12254.8 KKK24029.1 - 0.023 14.8 2.9 0.06 13.4 2.9 1.6 1 0 0 1 1 1 0 DNA polymerase alpha subunit p180 N terminal Frtz PF11768.8 KKK24029.1 - 0.047 12.0 0.0 0.59 8.4 0.0 2.1 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz IKI3 PF04762.12 KKK24029.1 - 0.05 11.6 0.6 0.16 9.9 0.0 2.1 2 1 0 2 2 2 0 IKI3 family TFIIIC_delta PF12657.7 KKK24029.1 - 0.089 12.7 0.1 2.2 8.1 0.1 2.6 2 1 0 2 2 2 0 Transcription factor IIIC subunit delta N-term Collagen_bind_2 PF12904.7 KKK24029.1 - 0.18 11.8 0.1 0.56 10.2 0.1 1.8 1 0 0 1 1 1 0 Putative collagen-binding domain of a collagenase ILVD_EDD PF00920.21 KKK24030.1 - 1.7e-164 548.3 0.3 1.9e-164 548.1 0.3 1.0 1 0 0 1 1 1 1 Dehydratase family MMU163 PF17119.5 KKK24031.1 - 1.5e-100 335.5 0.0 2.1e-100 335.0 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial protein up-regulated during meiosis MFS_1 PF07690.16 KKK24033.1 - 6.4e-39 133.9 32.4 5.1e-38 130.9 21.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KKK24033.1 - 5e-05 22.3 9.3 5e-05 22.3 9.3 2.2 1 1 1 2 2 2 1 Sugar (and other) transporter MFS_5 PF05631.14 KKK24033.1 - 0.001 18.1 1.8 0.0022 17.0 1.3 1.8 1 1 1 2 2 2 1 Sugar-tranasporters, 12 TM MFS_4 PF06779.14 KKK24033.1 - 0.0081 15.5 6.9 0.0081 15.5 6.9 2.5 2 1 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB DUF1129 PF06570.11 KKK24033.1 - 0.059 12.8 0.6 6 6.3 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) SF3A2 PF16835.5 KKK24037.1 - 2.3e-38 130.5 0.0 3.6e-38 129.8 0.0 1.3 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) zf-met PF12874.7 KKK24037.1 - 1.1e-05 25.7 0.5 2e-05 24.8 0.5 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type PRP4 PF08799.11 KKK24037.1 - 0.051 13.1 1.5 0.11 12.1 1.5 1.6 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like Pkinase PF00069.25 KKK24038.1 - 8.4e-56 189.2 0.0 1.3e-54 185.4 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK24038.1 - 3.9e-25 88.6 0.5 1.1e-19 70.7 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 KKK24038.1 - 5.9e-06 25.5 0.0 8.4e-06 25.0 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KKK24038.1 - 0.0002 21.4 0.2 0.024 14.5 0.2 2.5 1 1 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KKK24038.1 - 0.00041 19.8 0.0 0.00098 18.5 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KKK24038.1 - 0.00056 19.3 0.3 0.0015 17.9 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.11 KKK24038.1 - 0.0052 15.9 0.0 0.0086 15.2 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 FTA2 PF13095.6 KKK24038.1 - 0.022 14.4 0.2 4.5 6.8 0.1 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 KKK24038.1 - 0.068 11.9 0.0 0.13 11.0 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase TFIIA PF03153.13 KKK24038.1 - 0.093 12.7 9.2 0.14 12.1 9.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit NFACT-C PF11923.8 KKK24038.1 - 0.094 12.6 0.2 0.2 11.6 0.2 1.5 1 0 0 1 1 1 0 NFACT protein C-terminal domain PA28_alpha PF02251.18 KKK24038.1 - 0.16 12.1 0.1 1 9.5 0.0 2.3 2 0 0 2 2 2 0 Proteasome activator pa28 alpha subunit RIO1 PF01163.22 KKK24038.1 - 0.23 11.0 1.2 0.57 9.8 0.0 2.0 2 0 0 2 2 2 0 RIO1 family Tim54 PF11711.8 KKK24039.1 - 3.6e-137 457.1 1.5 9.5e-136 452.5 1.5 2.0 1 1 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 Fungal_trans PF04082.18 KKK24040.1 - 7.2e-16 58.0 5.8 1.1e-15 57.5 5.8 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK24040.1 - 3.4e-08 33.5 8.5 3.4e-08 33.5 8.5 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CAP_GLY PF01302.25 KKK24041.1 - 2.3e-19 69.1 0.4 5.4e-19 68.0 0.4 1.6 1 0 0 1 1 1 1 CAP-Gly domain LRR_4 PF12799.7 KKK24041.1 - 5.6e-09 36.1 10.7 0.0021 18.4 0.4 5.2 3 1 3 6 6 6 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KKK24041.1 - 3.5e-07 29.9 4.9 0.055 13.0 0.9 4.3 2 2 2 4 4 4 3 Leucine-rich repeat LRR_8 PF13855.6 KKK24041.1 - 3.4e-06 26.7 15.2 0.0045 16.7 1.2 4.5 2 2 1 4 4 4 3 Leucine rich repeat zf-U1 PF06220.12 KKK24041.1 - 9.6e-06 25.3 0.1 1.7e-05 24.5 0.1 1.4 1 0 0 1 1 1 1 U1 zinc finger LRR_6 PF13516.6 KKK24041.1 - 0.00022 21.0 6.4 0.38 10.9 0.2 5.8 6 0 0 6 6 6 1 Leucine Rich repeat LRR_1 PF00560.33 KKK24041.1 - 0.0012 19.1 6.4 22 6.1 0.3 5.6 5 0 0 5 5 5 0 Leucine Rich Repeat IF2_assoc PF08364.11 KKK24041.1 - 0.22 11.8 1.3 0.8 10.0 1.3 2.0 1 0 0 1 1 1 0 Bacterial translation initiation factor IF-2 associated region ABC_tran_Xtn PF12848.7 KKK24041.1 - 2.9 8.0 6.1 0.37 10.9 1.0 2.2 2 0 0 2 2 2 0 ABC transporter bZIP_2 PF07716.15 KKK24042.1 - 3.9e-06 26.9 9.8 1.1e-05 25.4 9.8 1.7 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 KKK24042.1 - 0.00035 20.6 10.2 0.0007 19.6 10.2 1.4 1 0 0 1 1 1 1 bZIP transcription factor Glyco_transf_9 PF01075.17 KKK24042.1 - 0.13 11.5 1.3 0.66 9.2 0.1 2.2 2 0 0 2 2 2 0 Glycosyltransferase family 9 (heptosyltransferase) LPD23 PF18838.1 KKK24042.1 - 0.14 11.9 0.8 0.34 10.7 0.8 1.6 1 0 0 1 1 1 0 Large polyvalent protein associated domain 23 TPR_14 PF13428.6 KKK24042.1 - 0.21 12.5 1.7 0.48 11.4 1.7 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat VPS9 PF02204.18 KKK24043.1 - 1e-29 102.8 0.0 1.7e-29 102.1 0.0 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF5601 PF18151.1 KKK24043.1 - 5e-16 58.8 0.2 1.4e-15 57.4 0.2 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF5601) CUE PF02845.16 KKK24043.1 - 1.8e-09 37.1 0.2 2.3e-08 33.6 0.0 2.3 2 0 0 2 2 2 1 CUE domain Fungal_trans PF04082.18 KKK24044.1 - 1.2e-18 67.1 0.2 1.8e-18 66.5 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK24044.1 - 1.1e-09 38.2 12.3 2.1e-09 37.4 12.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MMS22L_C PF14911.6 KKK24044.1 - 0.1 11.6 0.2 0.26 10.3 0.1 1.6 2 0 0 2 2 2 0 S-phase genomic integrity recombination mediator, C-terminal IFP_35_N PF07334.13 KKK24044.1 - 0.11 12.6 0.4 0.35 11.0 0.4 1.8 1 0 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Asn_synthase PF00733.21 KKK24045.1 - 5.9e-16 59.1 0.3 1e-05 25.4 0.0 3.1 2 1 1 3 3 3 3 Asparagine synthase GATase_7 PF13537.6 KKK24045.1 - 1.2e-06 28.4 0.0 1e-05 25.4 0.0 2.4 2 0 0 2 2 2 1 Glutamine amidotransferase domain DUF3700 PF12481.8 KKK24045.1 - 3.6e-06 26.6 0.0 6.9e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Aluminium induced protein GATase_6 PF13522.6 KKK24045.1 - 2.8e-05 24.3 0.0 0.00067 19.9 0.0 2.7 2 0 0 2 2 2 1 Glutamine amidotransferase domain VIT1 PF01988.19 KKK24047.1 - 3.5e-45 154.5 2.6 5.4e-45 153.9 2.6 1.3 1 0 0 1 1 1 1 VIT family F-box-like_2 PF13013.6 KKK24047.1 - 0.098 12.6 0.1 0.22 11.5 0.1 1.5 1 0 0 1 1 1 0 F-box-like domain DUF4202 PF13875.6 KKK24048.1 - 9.3e-52 175.6 0.0 1e-30 107.0 0.0 2.0 1 1 1 2 2 2 2 Domain of unknown function (DUF4202) Rox3 PF08633.10 KKK24049.1 - 5.8e-64 216.2 6.3 1.8e-63 214.5 1.5 2.2 2 0 0 2 2 2 2 Rox3 mediator complex subunit PBP1_TM PF14812.6 KKK24049.1 - 0.15 12.4 5.4 0.11 12.9 3.0 1.9 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Trp_DMAT PF11991.8 KKK24070.1 - 2.7e-75 254.0 0.0 3.6e-75 253.7 0.0 1.2 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase GTP_EFTU_D3 PF03143.17 KKK24076.1 - 2.9e-20 72.6 0.4 3.5e-20 72.4 0.0 1.3 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain Adaptin_N PF01602.20 KKK24083.1 - 6.9e-35 120.6 0.2 7.8e-35 120.4 0.2 1.0 1 0 0 1 1 1 1 Adaptin N terminal region DUF1160 PF06648.11 KKK24083.1 - 0.037 14.0 0.6 0.063 13.3 0.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1160) Peptidase_S48 PF03574.15 KKK24083.1 - 0.089 13.0 0.1 0.21 11.8 0.0 1.6 1 1 1 2 2 2 0 Peptidase family S48 Dak1 PF02733.17 KKK24084.1 - 2.6e-106 355.1 0.1 4.9e-106 354.1 0.1 1.5 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 KKK24084.1 - 1e-46 159.0 0.2 2.1e-46 158.0 0.2 1.6 1 0 0 1 1 1 1 DAK2 domain MFAP1 PF06991.11 KKK24085.1 - 1.3e-68 231.1 28.1 1.3e-68 231.1 28.1 3.3 2 1 0 3 3 3 1 Microfibril-associated/Pre-mRNA processing Rep_fac-A_3 PF08661.11 KKK24086.1 - 5.2e-24 84.6 0.0 5.7e-24 84.5 0.0 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 Ten1 PF12658.7 KKK24086.1 - 0.082 12.9 0.0 1.5 8.7 0.0 2.0 1 1 0 1 1 1 0 Telomere capping, CST complex subunit GATA PF00320.27 KKK24087.1 - 8.6e-06 25.3 4.5 0.00062 19.3 0.8 2.5 2 0 0 2 2 2 2 GATA zinc finger zf-RING_7 PF02591.15 KKK24087.1 - 0.072 13.3 0.8 0.17 12.1 0.8 1.6 1 0 0 1 1 1 0 C4-type zinc ribbon domain Mucin PF01456.17 KKK24094.1 - 0.032 14.2 20.4 0.048 13.7 20.4 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Opi1 PF08618.10 KKK24094.1 - 0.11 11.8 10.8 0.13 11.5 10.8 1.0 1 0 0 1 1 1 0 Transcription factor Opi1 SprA-related PF12118.8 KKK24094.1 - 0.88 8.7 18.8 1.1 8.3 18.8 1.1 1 0 0 1 1 1 0 SprA-related family Sporozoite_P67 PF05642.11 KKK24094.1 - 4.3 5.3 13.8 4.8 5.1 13.8 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Apt1 PF10351.9 KKK24094.1 - 9.4 5.0 7.1 11 4.8 7.1 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain PRK PF00485.18 KKK24095.1 - 0.00016 21.5 0.0 0.00023 21.0 0.0 1.3 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family NB-ARC PF00931.22 KKK24095.1 - 0.00089 18.5 0.0 0.0013 18.0 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain AAA_18 PF13238.6 KKK24095.1 - 0.017 15.7 0.1 0.16 12.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 KKK24095.1 - 0.036 14.4 0.0 0.065 13.6 0.0 1.8 1 1 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 KKK24095.1 - 0.048 13.8 0.2 4.2 7.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 KKK24095.1 - 0.07 12.2 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF2075 PF09848.9 KKK24095.1 - 0.07 12.4 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) RuvB_N PF05496.12 KKK24095.1 - 0.079 12.7 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Transpeptidase PF00905.22 KKK24095.1 - 0.096 11.9 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Penicillin binding protein transpeptidase domain DPBB_1 PF03330.18 KKK24096.1 - 9.6e-05 22.6 0.0 0.00031 21.0 0.0 2.0 1 0 0 1 1 1 1 Lytic transglycolase PAP1 PF08601.10 KKK24096.1 - 3.8 7.1 25.7 4.6 6.9 25.7 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 DUF572 PF04502.13 KKK24096.1 - 8 6.0 9.2 10 5.6 9.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Ribonuc_red_lgC PF02867.15 KKK24097.1 - 2.3e-186 620.4 0.0 3.5e-186 619.8 0.0 1.3 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 KKK24097.1 - 3.3e-24 84.7 0.0 7.9e-24 83.5 0.0 1.7 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 KKK24097.1 - 1.4e-16 60.8 0.1 3.2e-16 59.7 0.1 1.6 1 0 0 1 1 1 1 ATP cone domain ELFV_dehydrog PF00208.21 KKK24098.1 - 5.3e-84 281.8 1.9 6.6e-84 281.4 1.9 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 KKK24098.1 - 2.7e-50 169.6 0.0 4.9e-50 168.8 0.0 1.4 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain MFS_1 PF07690.16 KKK24099.1 - 8.3e-16 57.8 32.0 8.3e-16 57.8 32.0 4.1 3 1 1 4 4 4 3 Major Facilitator Superfamily Med5 PF08689.10 KKK24100.1 - 3.8e-199 664.1 0.0 4.7e-198 660.5 0.0 2.3 1 1 0 1 1 1 1 Mediator complex subunit Med5 zf-CCCH PF00642.24 KKK24100.1 - 0.18 11.8 0.1 0.37 10.8 0.1 1.4 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Mur_ligase_M PF08245.12 KKK24103.1 - 8.9e-06 25.8 0.1 1.7e-05 24.9 0.1 1.5 1 1 0 1 1 1 1 Mur ligase middle domain ABC1 PF03109.16 KKK24104.1 - 3.9e-33 114.1 0.0 6.7e-33 113.4 0.0 1.4 1 0 0 1 1 1 1 ABC1 family UCR_TM PF02921.14 KKK24104.1 - 0.16 12.5 0.0 0.47 11.0 0.0 1.7 1 0 0 1 1 1 0 Ubiquinol cytochrome reductase transmembrane region RIO1 PF01163.22 KKK24104.1 - 0.2 11.2 0.0 0.38 10.3 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Pkinase PF00069.25 KKK24105.1 - 9.1e-73 244.9 0.0 3.7e-72 242.9 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK24105.1 - 9.2e-51 172.6 0.0 2e-50 171.5 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KKK24105.1 - 0.00082 18.3 0.2 0.0034 16.2 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase Exo70 PF03081.15 KKK24105.1 - 0.038 13.0 1.2 0.37 9.8 0.2 2.2 2 0 0 2 2 2 0 Exo70 exocyst complex subunit Kinase-like PF14531.6 KKK24105.1 - 0.041 13.2 0.0 0.46 9.8 0.0 2.3 2 0 0 2 2 2 0 Kinase-like GerD PF17898.1 KKK24105.1 - 0.085 12.8 0.4 0.25 11.3 0.4 1.8 1 0 0 1 1 1 0 Spore germination GerD central core domain zf-CCCH_6 PF18585.1 KKK24105.1 - 0.3 11.0 1.2 17 5.4 0.0 3.8 4 0 0 4 4 4 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 2 Mito_carr PF00153.27 KKK24106.1 - 2.4e-60 200.5 2.9 3.6e-23 81.3 0.1 3.5 2 2 1 3 3 3 3 Mitochondrial carrier protein ERbeta_N PF12497.8 KKK24107.1 - 0.0021 17.8 1.1 0.0026 17.6 1.1 1.1 1 0 0 1 1 1 1 Estrogen receptor beta UCR_14kD PF02271.16 KKK24108.1 - 7.9e-45 150.9 0.1 9.1e-45 150.7 0.1 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit ArfGap PF01412.18 KKK24111.1 - 3.5e-34 117.4 2.2 6e-34 116.6 0.1 2.5 3 0 0 3 3 3 1 Putative GTPase activating protein for Arf BAR_3 PF16746.5 KKK24111.1 - 3.3e-21 76.1 14.4 6.8e-21 75.1 14.4 1.4 1 0 0 1 1 1 1 BAR domain of APPL family PH PF00169.29 KKK24111.1 - 3e-12 47.0 0.2 1.4e-11 44.8 0.2 2.3 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 KKK24111.1 - 0.0073 16.7 0.5 0.033 14.6 0.5 2.2 1 0 0 1 1 1 1 Pleckstrin homology domain YTH PF04146.15 KKK24112.1 - 1.7e-53 180.9 0.0 6e-53 179.2 0.0 1.9 2 0 0 2 2 2 1 YT521-B-like domain RRM_1 PF00076.22 KKK24112.1 - 2e-06 27.6 0.0 3.7e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_60s PF00428.19 KKK24112.1 - 0.17 12.5 5.8 3.8 8.2 5.8 2.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein SNF2_N PF00176.23 KKK24113.1 - 5.9e-51 173.2 0.3 1.5e-49 168.6 0.3 2.7 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KKK24113.1 - 1e-16 61.3 0.1 2e-15 57.1 0.0 3.0 4 0 0 4 4 4 1 Helicase conserved C-terminal domain ResIII PF04851.15 KKK24113.1 - 5.1e-06 26.6 0.0 1.4e-05 25.2 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.25 KKK24113.1 - 3.1e-05 23.7 10.5 3.1e-05 23.7 10.5 2.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) AAA_34 PF13872.6 KKK24113.1 - 0.0013 17.7 0.0 0.0034 16.3 0.0 1.6 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 C2 PF00168.30 KKK24114.1 - 6.6e-10 39.2 0.0 1.3e-09 38.3 0.0 1.5 1 0 0 1 1 1 1 C2 domain ATP-synt_B PF00430.18 KKK24116.1 - 5.1 7.2 7.2 8.8 6.4 7.2 1.3 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) LRR_4 PF12799.7 KKK24117.1 - 0.0017 18.7 8.1 15 6.2 0.1 6.5 5 1 3 8 8 8 1 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KKK24117.1 - 0.0037 17.2 6.2 7.7 6.9 0.0 6.1 8 0 0 8 8 8 2 Leucine Rich repeat FYVE PF01363.21 KKK24117.1 - 0.34 11.1 3.3 0.24 11.6 0.9 2.0 2 1 0 2 2 2 0 FYVE zinc finger ATP-synt_B PF00430.18 KKK24117.1 - 7.5 6.6 9.8 16 5.6 9.8 1.5 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) Glyco_transf_20 PF00982.21 KKK24118.1 - 2.3e-159 531.1 0.0 3e-159 530.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 KKK24118.1 - 4.1e-26 91.5 0.0 6.7e-26 90.9 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase Glycophorin_A PF01102.18 KKK24119.1 - 0.011 15.9 5.1 0.018 15.3 5.1 1.3 1 0 0 1 1 1 0 Glycophorin A RIFIN PF02009.16 KKK24119.1 - 0.094 12.6 2.3 0.11 12.4 2.3 1.1 1 0 0 1 1 1 0 Rifin Pox_A12 PF04651.13 KKK24119.1 - 0.14 12.2 6.6 0.21 11.6 6.6 1.2 1 0 0 1 1 1 0 Poxvirus A12 protein DUF2057 PF09829.9 KKK24119.1 - 0.16 12.1 5.2 0.21 11.7 5.2 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2057) Sporozoite_P67 PF05642.11 KKK24119.1 - 0.94 7.5 12.2 1.1 7.3 12.2 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen FSA_C PF10479.9 KKK24119.1 - 0.96 7.5 11.6 1 7.4 11.6 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus PBP3 PF18056.1 KKK24119.1 - 5.3 7.2 6.2 8.2 6.6 6.2 1.3 1 0 0 1 1 1 0 Penicillin Binding Protein 3 Domain Na_Ca_ex PF01699.24 KKK24120.1 - 1.3e-49 168.0 47.6 4e-27 95.0 16.9 2.6 3 0 0 3 3 3 2 Sodium/calcium exchanger protein BCAS2 PF05700.11 KKK24120.1 - 0.022 14.5 0.5 0.034 13.8 0.5 1.2 1 0 0 1 1 1 0 Breast carcinoma amplified sequence 2 (BCAS2) Herpes_gE PF02480.16 KKK24120.1 - 0.029 13.1 0.9 2.8 6.6 0.0 2.1 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E DUF4307 PF14155.6 KKK24120.1 - 1.7 8.5 3.3 4.2 7.2 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4307) Cnd2 PF05786.14 KKK24121.1 - 0 1052.0 0.5 0 1051.8 0.5 1.0 1 0 0 1 1 1 1 Condensin complex subunit 2 CNDH2_N PF06278.11 KKK24121.1 - 0.02 15.1 0.0 0.059 13.6 0.0 1.8 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal FNIP_N PF14636.6 KKK24121.1 - 0.91 10.5 4.8 12 6.9 0.6 2.7 2 0 0 2 2 2 0 Folliculin-interacting protein N-terminus RNA_pol_L_2 PF13656.6 KKK24122.1 - 1.2e-24 85.8 0.0 2e-24 85.1 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 KKK24122.1 - 1.2e-08 34.3 0.0 2.5e-08 33.2 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain EF-hand_4 PF12763.7 KKK24123.1 - 7.5e-27 93.3 0.0 1.1e-12 47.8 0.0 2.4 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand WH2 PF02205.20 KKK24123.1 - 1.2e-10 40.8 0.7 2.8e-10 39.7 0.7 1.7 1 0 0 1 1 1 1 WH2 motif DUF1720 PF08226.11 KKK24123.1 - 2.5e-05 24.6 41.0 2.5e-05 24.6 41.0 7.4 4 3 2 6 6 6 3 Domain of unknown function (DUF1720) EF-hand_7 PF13499.6 KKK24123.1 - 5.8e-05 23.5 1.5 0.034 14.6 0.0 3.6 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.32 KKK24123.1 - 0.014 14.9 0.0 5.5 6.8 0.0 2.5 2 0 0 2 2 2 0 EF hand E3_binding PF02817.17 KKK24123.1 - 0.095 13.1 0.8 0.47 10.9 0.1 2.6 3 0 0 3 3 3 0 e3 binding domain zf-H2C2_2 PF13465.6 KKK24124.1 - 0.00069 19.9 0.4 0.00069 19.9 0.4 2.1 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_6 PF13912.6 KKK24124.1 - 0.0014 18.5 0.0 0.0032 17.4 0.0 1.5 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2 PF00096.26 KKK24124.1 - 0.014 15.8 0.1 0.043 14.3 0.1 1.9 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2HC_2 PF13913.6 KKK24124.1 - 0.015 15.2 4.0 0.024 14.6 0.9 2.3 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2H2_4 PF13894.6 KKK24124.1 - 0.036 14.9 0.4 0.18 12.7 0.1 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger DUF3074 PF11274.8 KKK24125.1 - 4.4e-41 140.9 0.1 5.5e-41 140.6 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3074) MARVEL PF01284.23 KKK24126.1 - 0.00064 19.8 6.1 0.0091 16.0 3.8 2.3 2 0 0 2 2 2 1 Membrane-associating domain DUF2339 PF10101.9 KKK24126.1 - 0.00097 17.9 2.6 0.0013 17.5 2.6 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2339) DUF981 PF06168.11 KKK24126.1 - 0.016 15.1 2.4 0.026 14.5 2.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF981) DUF202 PF02656.15 KKK24126.1 - 0.03 14.8 0.9 0.03 14.8 0.9 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF202) DUF4381 PF14316.6 KKK24126.1 - 0.044 14.0 3.2 4 7.7 0.5 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) SPC25 PF06703.11 KKK24126.1 - 0.065 13.0 1.5 0.18 11.5 1.5 1.8 1 0 0 1 1 1 0 Microsomal signal peptidase 25 kDa subunit (SPC25) FixQ PF05545.11 KKK24126.1 - 0.1 12.6 9.6 0.65 10.0 0.0 3.2 2 1 1 3 3 3 0 Cbb3-type cytochrome oxidase component FixQ PEN-2 PF10251.9 KKK24126.1 - 0.1 13.0 8.9 0.051 14.0 4.0 2.6 3 0 0 3 3 3 0 Presenilin enhancer-2 subunit of gamma secretase Cation_efflux PF01545.21 KKK24126.1 - 0.11 12.2 0.1 0.11 12.2 0.1 1.9 2 0 0 2 2 2 0 Cation efflux family DUF1772 PF08592.11 KKK24126.1 - 0.14 12.5 4.0 0.12 12.6 1.8 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF1772) DUF4199 PF13858.6 KKK24126.1 - 1.1 9.7 7.7 0.14 12.6 0.7 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF4199) DUF3413 PF11893.8 KKK24126.1 - 5.1 6.2 11.4 2.5 7.2 7.6 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF3413) DUF2721 PF11026.8 KKK24126.1 - 5.5 6.9 7.9 5.4 6.9 0.8 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2721) DUF382 PF04037.13 KKK24130.1 - 5.5e-58 194.6 0.7 1.1e-57 193.6 0.7 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF382) PSP PF04046.16 KKK24130.1 - 1.2e-19 69.9 7.3 2.8e-19 68.7 7.3 1.7 1 0 0 1 1 1 1 PSP SPT16 PF08644.11 KKK24131.1 - 4.7e-57 192.4 0.1 1.2e-56 191.0 0.1 1.8 1 0 0 1 1 1 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.6 KKK24131.1 - 1.6e-53 180.8 0.0 1.1e-52 178.1 0.0 2.6 3 0 0 3 3 3 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.24 KKK24131.1 - 8.9e-26 90.9 0.0 1.5e-25 90.1 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.12 KKK24131.1 - 8e-14 51.8 0.2 3e-13 50.0 0.0 2.0 2 0 0 2 2 2 1 Histone chaperone Rttp106-like DUF3956 PF13104.6 KKK24131.1 - 0.19 12.0 0.1 0.37 11.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3956) Peptidase_M43 PF05572.13 KKK24132.1 - 6.9e-13 48.8 0.0 2e-12 47.2 0.0 1.8 2 0 0 2 2 2 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 KKK24132.1 - 0.0017 18.5 3.9 0.0061 16.7 3.9 2.0 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 KKK24132.1 - 0.0028 17.3 0.0 0.0057 16.3 0.0 1.6 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 KKK24132.1 - 0.006 17.1 0.2 0.012 16.1 0.2 1.6 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 KKK24132.1 - 0.092 12.6 2.7 0.26 11.1 2.7 2.0 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like CDC50 PF03381.15 KKK24133.1 - 5.8e-98 327.8 0.0 7.1e-98 327.6 0.0 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family DUF3185 PF11381.8 KKK24133.1 - 2.3 8.3 7.0 3.3 7.8 0.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3185) SWIRM PF04433.17 KKK24134.1 - 1.5e-11 44.5 0.0 2.9e-11 43.6 0.0 1.5 1 0 0 1 1 1 1 SWIRM domain Choline_transpo PF04515.12 KKK24135.1 - 8.7e-24 84.3 24.0 8.7e-24 84.3 24.0 2.4 2 0 0 2 2 2 1 Plasma-membrane choline transporter Ras PF00071.22 KKK24136.1 - 8.6e-48 162.0 0.0 7.9e-37 126.3 0.0 2.1 2 0 0 2 2 2 2 Ras family Roc PF08477.13 KKK24136.1 - 4.2e-28 98.0 0.0 1.1e-17 64.3 0.0 2.2 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKK24136.1 - 3.4e-11 42.9 0.0 2e-10 40.4 0.0 1.9 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KKK24136.1 - 1.2e-08 34.7 0.0 2.2e-07 30.6 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KKK24136.1 - 1.1e-05 24.9 0.0 2.8e-05 23.6 0.0 1.7 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KKK24136.1 - 0.00022 21.3 0.0 0.0025 17.9 0.0 2.4 2 1 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KKK24136.1 - 0.00099 19.1 0.0 0.35 10.8 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 KKK24136.1 - 0.084 13.1 0.3 0.52 10.6 0.3 2.2 1 1 0 1 1 1 0 AAA domain Flu_M1_C PF08289.11 KKK24136.1 - 0.14 12.4 0.0 0.22 11.7 0.0 1.3 1 0 0 1 1 1 0 Influenza Matrix protein (M1) C-terminal domain AAA_25 PF13481.6 KKK24136.1 - 0.14 11.7 0.0 18 4.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 KKK24136.1 - 0.17 12.3 0.2 1.6 9.1 0.1 2.0 2 0 0 2 2 2 0 AAA ATPase domain PMT PF02366.18 KKK24137.1 - 2.8e-87 292.4 16.4 2.8e-87 292.4 16.4 2.0 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 KKK24137.1 - 1.6e-62 210.6 18.2 1.6e-62 210.6 18.2 2.4 2 1 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 KKK24137.1 - 1.6e-37 129.2 0.4 2.5e-37 128.5 0.4 1.2 1 0 0 1 1 1 1 MIR domain Sugar_tr PF00083.24 KKK24138.1 - 9.7e-102 341.1 11.3 1.3e-101 340.8 11.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKK24138.1 - 1.4e-31 109.7 25.1 1.9e-31 109.3 17.6 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Mito_carr PF00153.27 KKK24138.1 - 9.3e-17 60.8 0.0 9.8e-11 41.4 0.0 2.8 2 0 0 2 2 2 2 Mitochondrial carrier protein MFS_2 PF13347.6 KKK24138.1 - 1.8e-06 26.8 18.4 3.7e-05 22.5 5.6 2.6 3 0 0 3 3 3 2 MFS/sugar transport protein MFS_1_like PF12832.7 KKK24138.1 - 0.003 16.5 4.3 0.52 9.1 1.3 2.3 1 1 0 2 2 2 2 MFS_1 like family Pro_isomerase PF00160.21 KKK24151.1 - 1.1e-29 103.7 0.0 4.8e-26 91.9 0.0 2.1 2 0 0 2 2 2 2 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Q_salvage PF10343.9 KKK24152.1 - 2.7e-137 457.0 0.0 3.6e-137 456.6 0.0 1.2 1 0 0 1 1 1 1 Potential Queuosine, Q, salvage protein family DUF1563 PF07599.11 KKK24152.1 - 0.23 11.6 0.8 0.42 10.7 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1563) ORC6 PF05460.13 KKK24153.1 - 1.1e-97 327.5 0.1 1.4e-97 327.1 0.1 1.0 1 0 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) Hamartin PF04388.12 KKK24153.1 - 0.42 9.2 8.0 0.59 8.7 8.0 1.2 1 0 0 1 1 1 0 Hamartin protein Zn_clus PF00172.18 KKK24154.1 - 0.00033 20.7 7.5 0.00056 20.0 7.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ZapB PF06005.12 KKK24154.1 - 0.0081 16.6 0.5 0.019 15.4 0.5 1.6 1 0 0 1 1 1 1 Cell division protein ZapB DivIC PF04977.15 KKK24154.1 - 0.013 15.2 0.4 0.027 14.2 0.4 1.4 1 0 0 1 1 1 0 Septum formation initiator TMCO5 PF14992.6 KKK24154.1 - 0.027 14.0 0.1 0.044 13.4 0.1 1.2 1 0 0 1 1 1 0 TMCO5 family MbeD_MobD PF04899.12 KKK24154.1 - 0.047 13.8 0.5 0.11 12.6 0.5 1.6 1 0 0 1 1 1 0 MbeD/MobD like HALZ PF02183.18 KKK24154.1 - 0.12 12.7 0.5 0.22 11.8 0.5 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper Cnn_1N PF07989.11 KKK24154.1 - 0.14 12.3 0.2 0.27 11.4 0.2 1.4 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 CENP-H PF05837.12 KKK24154.1 - 0.24 11.8 0.1 0.24 11.8 0.1 1.8 2 0 0 2 2 2 0 Centromere protein H (CENP-H) Macoilin PF09726.9 KKK24154.1 - 0.69 8.4 5.8 0.98 7.9 5.8 1.1 1 0 0 1 1 1 0 Macoilin family XRCC4 PF06632.12 KKK24154.1 - 0.76 8.6 13.9 1.2 7.9 0.4 2.2 2 0 0 2 2 2 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 Csm1_N PF18504.1 KKK24154.1 - 0.8 10.1 2.8 1.6 9.1 2.8 1.4 1 0 0 1 1 1 0 Csm1 N-terminal domain Spc24 PF08286.11 KKK24154.1 - 0.89 9.8 3.1 0.31 11.3 0.2 1.7 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 ADIP PF11559.8 KKK24154.1 - 2.4 8.2 6.4 0.18 11.9 0.8 1.8 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding FSA_C PF10479.9 KKK24154.1 - 4.4 5.3 7.6 7.8 4.5 7.6 1.3 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus DivIVA PF05103.13 KKK24154.1 - 6.1 6.9 5.8 0.77 9.8 0.1 2.1 2 0 0 2 2 2 0 DivIVA protein Slx4 PF09494.10 KKK24155.1 - 1.4e-24 85.8 0.0 2.7e-24 84.9 0.0 1.5 1 0 0 1 1 1 1 Slx4 endonuclease DUF1966 PF09260.11 KKK24156.1 - 1.5e-32 111.7 0.0 2.4e-32 111.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) Alpha-amylase PF00128.24 KKK24156.1 - 9.8e-05 22.1 0.0 0.00014 21.5 0.0 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain CGI-121 PF08617.10 KKK24157.1 - 7.3e-55 185.5 0.0 8.4e-55 185.3 0.0 1.0 1 0 0 1 1 1 1 Kinase binding protein CGI-121 AAA_assoc PF14363.6 KKK24157.1 - 0.025 14.9 0.2 0.11 12.8 0.1 2.2 1 1 1 2 2 2 0 Domain associated at C-terminal with AAA CAMP_factor PF07373.11 KKK24157.1 - 0.17 11.5 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 CAMP factor (Cfa) Bax1-I PF01027.20 KKK24158.1 - 6e-31 107.9 11.9 9.5e-31 107.2 11.9 1.3 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 VirB8 PF04335.13 KKK24158.1 - 0.25 11.1 0.8 15 5.3 0.1 2.3 2 0 0 2 2 2 0 VirB8 protein WD40 PF00400.32 KKK24159.1 - 3.8e-13 49.7 20.1 6.1e-06 26.9 0.5 6.7 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKK24159.1 - 4.6e-08 33.3 0.1 1.9 8.8 0.0 4.8 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KKK24159.1 - 0.001 19.0 0.0 0.013 15.4 0.0 2.5 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A zf-C2H2_aberr PF17017.5 KKK24159.1 - 0.013 15.7 0.2 0.038 14.1 0.0 1.8 2 0 0 2 2 2 0 Aberrant zinc-finger NFACT-R_1 PF05670.13 KKK24159.1 - 0.031 14.9 0.0 0.35 11.5 0.0 2.4 2 0 0 2 2 2 0 NFACT protein RNA binding domain zf-rbx1 PF12678.7 KKK24159.1 - 3.4 8.0 11.5 0.068 13.5 2.1 2.5 2 0 0 2 2 2 0 RING-H2 zinc finger domain Zn_ribbon_17 PF17120.5 KKK24159.1 - 4.1 7.1 10.9 9.7 5.9 10.1 2.0 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type FYVE_2 PF02318.16 KKK24159.1 - 7.4 6.8 5.4 7.7 6.8 2.4 2.2 2 0 0 2 2 2 0 FYVE-type zinc finger Kinesin PF00225.23 KKK24161.1 - 2.5e-116 388.3 0.0 3.8e-116 387.7 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain PMSR PF01625.21 KKK24161.1 - 3.5e-53 179.9 0.0 8.4e-53 178.6 0.0 1.7 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase Microtub_bd PF16796.5 KKK24161.1 - 6.5e-27 94.3 0.0 1.8e-26 92.9 0.0 1.8 1 0 0 1 1 1 1 Microtubule binding AAA_33 PF13671.6 KKK24161.1 - 0.0039 17.3 1.1 0.026 14.7 0.0 2.8 3 0 0 3 3 3 1 AAA domain cNMPbd_u2 PF16643.5 KKK24162.1 - 3.1e-36 125.2 6.6 6.7e-36 124.1 6.6 1.5 1 0 0 1 1 1 1 Unstructured region on cNMP-binding protein cNMP_binding PF00027.29 KKK24162.1 - 1.6e-34 117.8 0.0 4e-21 74.9 0.0 2.7 2 1 0 2 2 2 2 Cyclic nucleotide-binding domain LRR_6 PF13516.6 KKK24162.1 - 1.2e-10 40.6 2.5 0.64 10.2 0.0 8.3 9 0 0 9 9 9 3 Leucine Rich repeat LRR_4 PF12799.7 KKK24162.1 - 3.3e-07 30.5 4.6 0.27 11.7 0.0 7.1 7 1 0 8 8 8 1 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KKK24162.1 - 0.00018 21.3 0.2 0.00061 19.6 0.2 1.9 1 0 0 1 1 1 1 F-box-like LRR_1 PF00560.33 KKK24162.1 - 0.0011 19.2 8.8 68 4.6 0.0 8.1 7 1 1 8 8 8 0 Leucine Rich Repeat F-box PF00646.33 KKK24162.1 - 0.0013 18.5 0.2 0.0013 18.5 0.2 2.4 3 0 0 3 3 3 1 F-box domain Cupin_3 PF05899.12 KKK24162.1 - 0.012 15.3 0.5 1.1 9.0 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF861) SAM_Ste50p PF09235.10 KKK24162.1 - 0.11 12.8 1.5 5.7 7.3 0.3 3.5 3 1 0 3 3 3 0 Ste50p, sterile alpha motif Tim17 PF02466.19 KKK24163.1 - 0.0031 17.9 1.5 0.0049 17.2 1.4 1.5 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Dr_adhesin PF12393.8 KKK24163.1 - 0.22 11.9 2.1 0.53 10.7 2.1 1.7 1 0 0 1 1 1 0 Dr family adhesin UCR_Fe-S_N PF10399.9 KKK24163.1 - 0.26 10.7 2.2 0.41 10.0 0.1 2.2 2 0 0 2 2 2 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Alk_phosphatase PF00245.20 KKK24164.1 - 3.6e-106 355.6 0.0 4.5e-106 355.3 0.0 1.1 1 0 0 1 1 1 1 Alkaline phosphatase DUF498 PF04430.14 KKK24164.1 - 0.00018 21.6 0.0 0.00043 20.3 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) Metalloenzyme PF01676.18 KKK24164.1 - 0.00025 20.5 0.0 0.00046 19.6 0.0 1.4 1 0 0 1 1 1 1 Metalloenzyme superfamily ABC_membrane PF00664.23 KKK24165.1 - 1e-36 127.0 11.4 2.3e-36 125.9 11.4 1.6 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 KKK24165.1 - 1.5e-33 116.2 0.0 3.4e-33 115.0 0.0 1.7 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KKK24165.1 - 5.7e-07 29.2 0.6 2.8e-05 23.7 0.0 2.7 2 1 1 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KKK24165.1 - 0.0061 16.8 0.1 0.035 14.4 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KKK24165.1 - 0.015 15.7 3.0 0.34 11.3 3.0 2.6 1 1 0 1 1 1 0 AAA ATPase domain SbcCD_C PF13558.6 KKK24165.1 - 0.025 14.8 1.1 0.46 10.7 0.3 3.1 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 KKK24165.1 - 0.039 13.7 0.1 0.1 12.4 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KKK24165.1 - 0.067 13.1 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase Ca_bind_SSO6904 PF18249.1 KKK24166.1 - 0.095 13.1 0.3 19 5.7 0.1 2.6 3 0 0 3 3 3 0 Calcium binding protein SSO6904 Glyco_hydro_16 PF00722.21 KKK24167.1 - 1.6e-46 158.0 6.8 1.6e-46 158.0 6.8 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 WAP PF00095.21 KKK24167.1 - 0.019 15.3 3.3 0.037 14.4 3.3 1.4 1 0 0 1 1 1 0 WAP-type (Whey Acidic Protein) 'four-disulfide core' Chitin_bind_1 PF00187.19 KKK24167.1 - 0.48 10.9 14.0 1 9.9 14.0 1.5 1 0 0 1 1 1 0 Chitin recognition protein DUF1180 PF06679.12 KKK24167.1 - 0.73 10.2 4.3 1.2 9.5 4.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Sugar_tr PF00083.24 KKK24169.1 - 2.9e-127 425.3 29.4 3.3e-127 425.1 29.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKK24169.1 - 7.9e-24 84.2 56.0 4.3e-21 75.2 31.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Phage_holin_3_2 PF04550.12 KKK24169.1 - 0.4 11.2 5.7 0.64 10.6 4.5 2.0 2 0 0 2 2 2 0 Phage holin family 2 Aminotran_5 PF00266.19 KKK24179.1 - 6.1e-20 71.5 0.0 1e-19 70.7 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 KKK24179.1 - 2.8e-06 26.8 0.0 4.3e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II GYF PF02213.16 KKK24180.1 - 1.3e-18 66.3 0.3 2.8e-18 65.3 0.3 1.6 1 0 0 1 1 1 1 GYF domain SpoIIP PF07454.11 KKK24180.1 - 0.88 9.0 6.5 2.9 7.3 6.5 1.9 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) ALS2CR11 PF15729.5 KKK24180.1 - 1.9 7.6 6.0 3.2 6.8 6.0 1.3 1 0 0 1 1 1 0 Amyotrophic lateral sclerosis 2 candidate 11 Med21 PF11221.8 KKK24181.1 - 9.9e-57 191.2 2.7 1.9e-56 190.3 2.7 1.4 1 1 0 1 1 1 1 Subunit 21 of Mediator complex Med9 PF07544.13 KKK24181.1 - 0.014 15.5 3.2 0.051 13.7 0.2 2.4 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DUF4455 PF14643.6 KKK24181.1 - 0.064 11.9 0.3 0.089 11.4 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4455) Cortex-I_coil PF09304.10 KKK24181.1 - 0.23 11.7 4.3 1.2 9.4 4.3 1.9 1 1 0 1 1 1 0 Cortexillin I, coiled coil SlyX PF04102.12 KKK24181.1 - 1 10.0 4.5 46 4.7 0.0 2.9 2 1 0 2 2 2 0 SlyX SNF2_N PF00176.23 KKK24182.1 - 8.1e-58 195.8 0.1 1.2e-57 195.2 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KKK24182.1 - 3.9e-13 49.7 0.0 4.6e-11 43.0 0.0 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KKK24182.1 - 2.7e-05 24.0 0.0 5.8e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KKK24182.1 - 0.00058 19.9 0.0 0.0013 18.8 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-RING_5 PF14634.6 KKK24182.1 - 0.014 15.3 1.0 0.024 14.6 1.0 1.4 1 0 0 1 1 1 0 zinc-RING finger domain DZR PF12773.7 KKK24182.1 - 1 9.4 2.5 2.3 8.3 2.5 1.6 1 0 0 1 1 1 0 Double zinc ribbon PI3_PI4_kinase PF00454.27 KKK24183.1 - 7.6e-27 94.7 0.0 8.2e-24 84.8 0.0 2.3 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase zf-RING_2 PF13639.6 KKK24184.1 - 1.5e-13 50.8 8.9 1.5e-13 50.8 8.9 2.3 2 0 0 2 2 2 1 Ring finger domain zf-RING_11 PF17123.5 KKK24184.1 - 5e-13 48.5 2.7 1.1e-12 47.4 2.7 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KKK24184.1 - 1.1e-09 38.0 9.0 1.1e-09 38.0 9.0 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KKK24184.1 - 5e-09 35.9 10.3 9.2e-08 31.8 4.2 2.2 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KKK24184.1 - 3.1e-06 27.0 7.8 3.1e-06 27.0 7.8 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KKK24184.1 - 3.4e-06 27.0 3.6 3.4e-06 27.0 3.6 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 KKK24184.1 - 1.4e-05 24.9 5.6 1.4e-05 24.9 5.6 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-rbx1 PF12678.7 KKK24184.1 - 1.6e-05 25.1 12.6 1.6e-05 25.1 12.6 2.1 2 1 0 2 2 2 1 RING-H2 zinc finger domain zinc_ribbon_9 PF14369.6 KKK24184.1 - 0.0004 20.6 6.2 0.011 16.0 2.8 2.6 2 0 0 2 2 2 1 zinc-ribbon Prok-RING_4 PF14447.6 KKK24184.1 - 0.00042 20.1 6.3 0.00042 20.1 6.3 2.3 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 KKK24184.1 - 0.00099 19.1 3.3 0.00099 19.1 3.3 1.8 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger HypA PF01155.19 KKK24184.1 - 0.0082 16.2 6.0 0.017 15.1 0.3 2.2 2 0 0 2 2 2 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-UDP PF14569.6 KKK24184.1 - 0.02 15.0 3.3 0.62 10.2 0.5 2.6 2 0 0 2 2 2 0 Zinc-binding RING-finger DZR PF12773.7 KKK24184.1 - 0.034 14.2 7.0 1.3 9.1 0.4 2.4 2 0 0 2 2 2 0 Double zinc ribbon Rad50_zn_hook PF04423.14 KKK24184.1 - 0.23 11.3 1.2 13 5.7 0.0 2.4 2 0 0 2 2 2 0 Rad50 zinc hook motif zinc-ribbons_6 PF07191.12 KKK24184.1 - 0.48 10.4 7.4 3.3 7.8 0.1 2.8 2 1 0 2 2 2 0 zinc-ribbons zinc_ribbon_4 PF13717.6 KKK24184.1 - 0.93 9.5 6.7 35 4.4 0.0 4.0 4 0 0 4 4 4 0 zinc-ribbon domain TF_Zn_Ribbon PF08271.12 KKK24184.1 - 1.4 8.5 4.1 25 4.5 0.0 3.1 3 0 0 3 3 3 0 TFIIB zinc-binding zf-RING_4 PF14570.6 KKK24184.1 - 1.7 8.5 12.8 0.2 11.5 4.4 2.4 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.8 KKK24184.1 - 1.8 8.8 9.5 1.3 9.3 6.0 2.4 2 1 0 2 2 2 0 FANCL C-terminal domain TackOD1 PF18551.1 KKK24184.1 - 1.9 8.1 7.2 3.4 7.3 0.3 2.4 2 1 0 2 2 2 0 Thaumarchaeal output domain 1 Zn_ribbon_17 PF17120.5 KKK24184.1 - 2.7 7.7 15.2 0.066 12.8 7.7 2.0 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type PHD PF00628.29 KKK24184.1 - 4 7.4 14.4 0.99 9.3 7.2 2.4 2 0 0 2 2 2 0 PHD-finger Spc24 PF08286.11 KKK24185.1 - 3.7e-37 126.8 1.4 1.7e-35 121.4 0.0 2.2 2 0 0 2 2 2 1 Spc24 subunit of Ndc80 CLZ PF16526.5 KKK24185.1 - 0.0013 19.1 6.3 0.11 12.9 1.7 2.4 2 0 0 2 2 2 2 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF4795 PF16043.5 KKK24185.1 - 0.02 14.5 2.7 0.052 13.1 2.7 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) Prefoldin_2 PF01920.20 KKK24185.1 - 0.039 13.9 4.0 2.1 8.3 0.8 2.2 2 0 0 2 2 2 0 Prefoldin subunit Streptin-Immun PF11083.8 KKK24185.1 - 0.097 13.1 0.3 1.6 9.2 0.0 2.2 2 0 0 2 2 2 0 Lantibiotic streptin immunity protein SlyX PF04102.12 KKK24185.1 - 0.15 12.7 6.2 0.51 11.0 0.6 2.4 2 0 0 2 2 2 0 SlyX WXG100 PF06013.12 KKK24185.1 - 0.34 11.2 2.1 1.6 9.0 0.1 2.6 3 0 0 3 3 3 0 Proteins of 100 residues with WXG DMPK_coil PF08826.10 KKK24185.1 - 0.5 10.5 9.6 0.42 10.8 0.8 2.2 2 0 0 2 2 2 0 DMPK coiled coil domain like TPR_MLP1_2 PF07926.12 KKK24185.1 - 0.61 10.2 10.7 6.9 6.7 10.7 2.0 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein APG6_N PF17675.1 KKK24185.1 - 0.88 10.1 9.7 1.3 9.6 9.7 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region HR1 PF02185.16 KKK24185.1 - 1.7 8.8 9.6 2 8.6 0.7 2.3 2 0 0 2 2 2 0 Hr1 repeat Rx_N PF18052.1 KKK24185.1 - 2.5 8.4 7.6 10 6.5 2.2 2.2 1 1 0 2 2 2 0 Rx N-terminal domain FlaC_arch PF05377.11 KKK24185.1 - 2.5 8.6 5.6 14 6.1 0.4 2.7 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Fis1_TPR_C PF14853.6 KKK24186.1 - 1.2e-24 86.1 0.4 1.9e-24 85.5 0.4 1.3 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.6 KKK24186.1 - 3.4e-18 65.0 0.1 5.9e-18 64.2 0.1 1.4 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_2 PF07719.17 KKK24186.1 - 0.0068 16.4 1.1 0.0068 16.4 1.1 1.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 KKK24186.1 - 0.084 13.5 0.1 0.16 12.7 0.1 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat Sugar_tr PF00083.24 KKK24209.1 - 8.1e-94 315.0 21.4 9.8e-94 314.7 21.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKK24209.1 - 9e-15 54.4 40.1 5.8e-09 35.3 10.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Nop14 PF04147.12 KKK24210.1 - 7.5 4.6 20.0 0.49 8.5 6.8 2.0 2 0 0 2 2 2 0 Nop14-like family BUD22 PF09073.10 KKK24210.1 - 7.6 5.8 19.4 0.5 9.6 7.4 2.1 2 0 0 2 2 2 0 BUD22 PGM_PMM_I PF02878.16 KKK24211.1 - 1.5e-31 108.9 0.1 2.8e-31 108.1 0.1 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 KKK24211.1 - 8.8e-26 90.3 0.0 1.8e-25 89.3 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III RNase_T PF00929.24 KKK24211.1 - 4.2e-20 72.9 0.0 7.7e-20 72.1 0.0 1.4 1 0 0 1 1 1 1 Exonuclease PGM_PMM_II PF02879.16 KKK24211.1 - 1e-14 55.0 0.0 2.1e-14 54.0 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 KKK24211.1 - 5.4e-07 29.7 0.0 1.2e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain GFO_IDH_MocA PF01408.22 KKK24212.1 - 6.9e-07 30.1 0.0 1.4e-06 29.1 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Ilar_coat PF01787.16 KKK24212.1 - 0.098 12.4 0.1 0.19 11.5 0.1 1.5 1 0 0 1 1 1 0 Ilarvirus coat protein FSA_C PF10479.9 KKK24212.1 - 0.62 8.1 3.7 0.86 7.7 3.7 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus AICARFT_IMPCHas PF01808.18 KKK24217.1 - 3.5e-91 305.7 0.0 5.6e-91 305.1 0.0 1.3 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.22 KKK24217.1 - 4.7e-25 87.6 0.0 9e-25 86.7 0.0 1.5 1 0 0 1 1 1 1 MGS-like domain NUDIX PF00293.28 KKK24265.1 - 1.6e-09 37.9 0.0 3.2e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain CBFD_NFYB_HMF PF00808.23 KKK24265.1 - 0.00083 19.6 0.0 0.0017 18.6 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-W PF15510.6 KKK24265.1 - 0.00093 19.4 0.1 0.0021 18.2 0.1 1.6 1 0 0 1 1 1 1 CENP-W protein Frag1 PF10277.9 KKK24266.1 - 2.1e-11 43.8 0.0 3.6e-11 43.0 0.0 1.3 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family Trypan_PARP PF05887.11 KKK24266.1 - 2.3e-08 34.1 3.3 4e-08 33.3 3.3 1.4 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) SPESP1 PF15754.5 KKK24266.1 - 0.005 16.1 3.3 0.0069 15.6 3.3 1.1 1 0 0 1 1 1 1 Sperm equatorial segment protein 1 PBP_N PF17093.5 KKK24266.1 - 0.059 13.6 0.0 0.1 12.8 0.0 1.4 1 0 0 1 1 1 0 Penicillin-binding protein N-terminus DUF4366 PF14283.6 KKK24266.1 - 0.25 11.4 0.3 0.69 10.0 0.3 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) DSBA PF01323.20 KKK24267.1 - 4e-31 108.3 0.0 9.7e-15 54.8 0.0 2.0 2 0 0 2 2 2 2 DSBA-like thioredoxin domain OmpA_like PF16961.5 KKK24267.1 - 0.054 13.2 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Putative OmpA-OmpF-like porin family IPPT PF01715.17 KKK24267.1 - 0.09 12.6 0.0 0.26 11.1 0.0 1.7 1 1 0 1 1 1 0 IPP transferase Sod_Fe_C PF02777.18 KKK24268.1 - 2.1e-16 59.9 0.1 1.7e-13 50.6 0.1 2.3 1 1 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 KKK24268.1 - 0.048 14.1 0.1 0.088 13.3 0.1 1.4 1 0 0 1 1 1 0 Iron/manganese superoxide dismutases, alpha-hairpin domain DAD PF02109.16 KKK24269.1 - 0.054 13.8 0.0 0.1 13.0 0.0 1.4 1 0 0 1 1 1 0 DAD family Apt1 PF10351.9 KKK24269.1 - 0.55 9.0 6.1 0.7 8.7 6.1 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain FMN_dh PF01070.18 KKK24270.1 - 2.2e-106 355.8 0.0 2.9e-106 355.4 0.0 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 KKK24270.1 - 4.2e-20 71.7 0.0 9.7e-20 70.5 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 KKK24270.1 - 2.8e-06 26.7 0.0 4.4e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 KKK24270.1 - 5.3e-05 22.4 0.0 0.00018 20.7 0.0 1.8 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.21 KKK24270.1 - 0.019 14.4 0.0 0.047 13.2 0.0 1.5 1 0 0 1 1 1 0 Histidine biosynthesis protein NMO PF03060.15 KKK24270.1 - 0.12 11.7 0.2 0.2 11.0 0.2 1.3 1 0 0 1 1 1 0 Nitronate monooxygenase Fungal_trans PF04082.18 KKK24271.1 - 1.6e-21 76.6 0.1 4.9e-21 75.0 0.1 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Polyketide_cyc PF03364.20 KKK24271.1 - 7.2e-17 61.8 0.0 1.9e-16 60.5 0.0 1.7 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport VTC PF09359.10 KKK24272.1 - 9.2e-88 294.2 0.1 1.5e-87 293.5 0.1 1.4 1 0 0 1 1 1 1 VTC domain DUF202 PF02656.15 KKK24272.1 - 1.9e-12 47.5 4.4 1.9e-12 47.5 4.4 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF202) SPX PF03105.19 KKK24272.1 - 0.00022 21.3 19.5 0.0064 16.5 0.0 4.4 3 1 1 5 5 5 3 SPX domain DUF4944 PF16302.5 KKK24272.1 - 0.11 12.6 0.1 0.26 11.4 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4944) INCENP_ARK-bind PF03941.15 KKK24272.1 - 0.57 10.2 0.0 0.57 10.2 0.0 2.6 3 0 0 3 3 3 0 Inner centromere protein, ARK binding region 6PF2K PF01591.18 KKK24273.1 - 5.7e-68 228.6 0.0 4.8e-48 163.4 0.0 2.2 2 0 0 2 2 2 2 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 KKK24273.1 - 1.1e-31 110.1 0.1 1.3e-23 83.8 0.0 2.5 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 KKK24273.1 - 0.00016 21.8 0.0 0.055 13.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain KTI12 PF08433.10 KKK24273.1 - 0.06 12.8 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 DUF202 PF02656.15 KKK24274.1 - 2.9e-05 24.4 2.9 2.9e-05 24.4 2.9 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF202) DUF998 PF06197.13 KKK24274.1 - 0.021 14.4 4.8 0.78 9.3 1.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF998) Muted PF14942.6 KKK24275.1 - 0.86 9.9 7.6 1.9 8.9 7.6 1.6 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein SurA_N_3 PF13624.6 KKK24275.1 - 0.91 9.3 6.7 0.52 10.1 3.2 1.9 1 1 1 2 2 2 0 SurA N-terminal domain Ax_dynein_light PF10211.9 KKK24275.1 - 1.1 9.2 8.2 2 8.3 8.2 1.4 1 0 0 1 1 1 0 Axonemal dynein light chain PIG-S PF10510.9 KKK24276.1 - 5.7e-185 616.0 0.6 5.7e-185 616.0 0.6 2.0 2 0 0 2 2 2 1 Phosphatidylinositol-glycan biosynthesis class S protein FmiP_Thoc5 PF09766.9 KKK24276.1 - 3.2e-28 99.1 17.6 5.9e-28 98.2 17.6 1.4 1 0 0 1 1 1 1 Fms-interacting protein/Thoc5 Cdh1_DBD_1 PF18196.1 KKK24276.1 - 0.24 11.7 3.3 0.51 10.7 3.3 1.4 1 0 0 1 1 1 0 Chromodomain helicase DNA-binding domain 1 DUF4200 PF13863.6 KKK24276.1 - 0.73 10.2 15.6 1.1 9.6 0.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Mod_r PF07200.13 KKK24276.1 - 1.1 9.3 13.8 14 5.7 8.8 2.7 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein YabA PF06156.13 KKK24276.1 - 3.5 8.3 9.5 31 5.3 0.1 2.5 2 0 0 2 2 2 0 Initiation control protein YabA DUF349 PF03993.12 KKK24276.1 - 5.1 7.5 9.6 51 4.3 0.3 2.7 1 1 1 2 2 2 0 Domain of Unknown Function (DUF349) Phage_TTP_12 PF16461.5 KKK24277.1 - 0.093 12.4 0.0 0.1 12.3 0.0 1.1 1 0 0 1 1 1 0 Lambda phage tail tube protein, TTP Pkinase PF00069.25 KKK24278.1 - 3.4e-05 23.3 0.0 5.2e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KKK24278.1 - 0.0015 18.0 0.0 0.0021 17.5 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 KKK24278.1 - 0.011 15.4 0.0 0.03 14.0 0.0 1.6 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 DUF3016 PF11454.8 KKK24278.1 - 0.073 12.8 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3016) Phos_pyr_kin PF08543.12 KKK24279.1 - 9.8e-12 44.8 0.0 2.5e-11 43.5 0.0 1.7 1 1 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 KKK24279.1 - 3.8e-06 26.4 0.7 9.7e-06 25.1 0.0 2.0 2 0 0 2 2 2 1 pfkB family carbohydrate kinase Dynactin PF12455.8 KKK24281.1 - 0.035 13.3 0.1 0.052 12.8 0.1 1.2 1 0 0 1 1 1 0 Dynein associated protein Afi1 PF07792.12 KKK24282.1 - 1.3e-45 155.1 1.1 2.3e-45 154.3 1.1 1.4 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking SPA PF08616.10 KKK24282.1 - 2.2e-37 127.5 0.0 3.7e-37 126.8 0.0 1.4 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.9 KKK24282.1 - 2.1e-08 33.3 0.2 0.0098 14.6 0.0 3.6 3 1 1 4 4 4 3 Transport protein Avl9 DUF2347 PF09804.9 KKK24282.1 - 0.036 13.6 0.0 0.11 12.0 0.0 1.8 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) RabGAP-TBC PF00566.18 KKK24283.1 - 1.1e-28 100.4 0.0 4.7e-24 85.2 0.0 2.2 2 0 0 2 2 2 2 Rab-GTPase-TBC domain EF-hand_6 PF13405.6 KKK24283.1 - 5.6e-12 44.6 2.0 1.8e-05 24.3 0.3 2.9 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 KKK24283.1 - 5.3e-11 41.3 2.8 3.2e-05 23.2 0.7 2.8 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 KKK24283.1 - 1.4e-08 35.0 0.9 7.1e-08 32.8 0.6 2.2 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 KKK24283.1 - 2.9e-06 26.5 9.4 0.0088 15.5 1.3 3.1 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 KKK24283.1 - 1.4e-05 24.9 0.6 0.14 12.0 0.2 2.8 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.6 KKK24283.1 - 0.02 15.2 0.1 9.7 6.6 0.0 2.9 2 1 0 2 2 2 0 EF-hand domain DUF4398 PF14346.6 KKK24283.1 - 0.081 13.6 0.4 0.22 12.2 0.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4398) RRM_1 PF00076.22 KKK24284.1 - 3.2e-18 65.3 0.0 6.1e-14 51.6 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Glyco_hydro_18 PF00704.28 KKK24285.1 - 1.1e-69 235.6 2.1 1.6e-69 235.0 2.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 KKK24285.1 - 4.2e-14 52.7 41.9 3.1e-13 49.9 17.4 6.4 6 2 0 6 6 6 2 Chitin recognition protein Glyco_hydro_114 PF03537.13 KKK24285.1 - 0.0086 15.4 0.0 0.25 10.6 0.0 2.8 2 1 0 2 2 2 1 Glycoside-hydrolase family GH114 Ank_2 PF12796.7 KKK24286.1 - 8.5e-25 87.2 0.0 4.2e-09 36.9 0.0 4.3 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KKK24286.1 - 5.4e-15 55.6 5.8 3.5e-05 24.3 0.0 6.9 3 2 4 8 8 8 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KKK24286.1 - 5.4e-13 47.9 3.5 0.15 12.7 0.1 7.6 8 0 0 8 8 8 3 Ankyrin repeat Ank PF00023.30 KKK24286.1 - 9.2e-10 38.5 6.3 0.055 13.9 0.0 6.5 7 1 0 7 7 7 3 Ankyrin repeat Ank_5 PF13857.6 KKK24286.1 - 4.4e-08 33.3 0.3 0.15 12.4 0.0 5.7 4 1 2 6 6 6 2 Ankyrin repeats (many copies) APH PF01636.23 KKK24287.1 - 4.3e-35 121.8 0.0 4.3e-33 115.2 0.0 2.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 KKK24287.1 - 7.8e-05 22.1 0.0 0.00013 21.4 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase RIO1 PF01163.22 KKK24287.1 - 0.002 17.8 0.0 0.18 11.4 0.0 2.5 2 1 0 2 2 2 1 RIO1 family Choline_kinase PF01633.20 KKK24287.1 - 0.0021 17.7 0.0 0.0036 16.9 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Fructosamin_kin PF03881.14 KKK24287.1 - 0.0058 15.9 0.0 3.1 6.9 0.0 2.6 2 1 0 2 2 2 2 Fructosamine kinase DUF1679 PF07914.11 KKK24287.1 - 0.035 13.0 0.0 1.1 8.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) DPM2 PF07297.12 KKK24288.1 - 1.5e-32 111.7 1.7 1.7e-32 111.6 1.7 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PIG-P PF08510.12 KKK24288.1 - 0.0083 16.0 0.9 0.01 15.7 0.9 1.1 1 0 0 1 1 1 1 PIG-P Phage_holin_3_6 PF07332.11 KKK24288.1 - 0.034 14.2 2.4 0.04 14.0 2.4 1.1 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III LapA_dom PF06305.11 KKK24288.1 - 0.048 13.5 0.1 0.048 13.5 0.1 1.7 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain DUF4229 PF14012.6 KKK24288.1 - 0.052 13.6 1.3 0.12 12.5 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4229) MA3 PF02847.17 KKK24289.1 - 1.4e-28 99.1 0.0 3.4e-28 97.9 0.0 1.7 2 0 0 2 2 2 1 MA3 domain WD40 PF00400.32 KKK24290.1 - 1.4e-17 63.7 9.1 1.4e-05 25.8 0.2 6.8 6 0 0 6 6 6 4 WD domain, G-beta repeat SET PF00856.28 KKK24290.1 - 6.3e-05 23.4 0.0 0.0019 18.6 0.0 3.2 2 1 0 2 2 2 1 SET domain ANAPC4_WD40 PF12894.7 KKK24290.1 - 0.0028 17.9 0.0 0.13 12.5 0.0 2.8 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain TPR_9 PF13371.6 KKK24290.1 - 0.018 15.2 0.9 0.057 13.6 0.9 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat CAP_N PF01213.19 KKK24290.1 - 6 6.2 6.2 13 5.1 6.2 1.5 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Glucosamine_iso PF01182.20 KKK24292.1 - 2.5e-67 227.1 0.0 2.8e-67 226.9 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase zf_UBZ PF18439.1 KKK24293.1 - 0.012 15.2 0.7 3.1 7.5 0.1 2.2 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-FPG_IleRS PF06827.14 KKK24293.1 - 0.82 9.6 0.1 0.82 9.6 0.1 2.4 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS Myb_DNA-binding PF00249.31 KKK24294.1 - 4.4e-10 39.6 0.0 1.1e-05 25.5 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 KKK24294.1 - 0.0017 18.2 1.2 0.0023 17.8 0.0 1.8 2 0 0 2 2 2 1 Myb DNA-binding like Myb_DNA-bind_6 PF13921.6 KKK24294.1 - 0.063 13.5 0.2 0.66 10.3 0.2 2.3 2 0 0 2 2 2 0 Myb-like DNA-binding domain p450 PF00067.22 KKK24295.1 - 1.4e-61 208.7 0.0 1.6e-61 208.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Aa_trans PF01490.18 KKK24296.1 - 9.4e-54 182.7 37.1 1.1e-53 182.5 37.1 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Phage_holin_3_7 PF05449.11 KKK24296.1 - 3.9 7.5 6.9 0.25 11.4 0.4 2.5 2 1 0 2 2 2 0 Putative 3TM holin, Phage_holin_3 HMG-CoA_red PF00368.18 KKK24297.1 - 4.2e-133 443.9 7.2 5.5e-133 443.5 7.2 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase HPIH PF13323.6 KKK24297.1 - 4.8e-34 117.5 0.0 9e-34 116.6 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain with HPIH motif Sterol-sensing PF12349.8 KKK24297.1 - 1.8e-14 53.9 1.3 3.7e-12 46.3 0.5 2.8 2 1 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 KKK24297.1 - 0.88 7.6 2.4 0.5 8.4 0.3 1.6 2 0 0 2 2 2 0 Patched family DUF3138 PF11336.8 KKK24298.1 - 0.025 13.2 0.4 0.035 12.7 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) SKG6 PF08693.10 KKK24301.1 - 1.1e-07 31.2 5.6 1.1e-07 31.2 5.6 3.1 3 0 0 3 3 3 1 Transmembrane alpha-helix domain DcuC PF03606.15 KKK24301.1 - 0.0023 16.4 0.0 0.0036 15.8 0.0 1.2 1 0 0 1 1 1 1 C4-dicarboxylate anaerobic carrier Phage_holin_2_4 PF16082.5 KKK24301.1 - 0.025 14.3 0.9 0.025 14.3 0.9 2.4 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like RIFIN PF02009.16 KKK24301.1 - 0.032 14.1 0.0 0.032 14.1 0.0 2.2 1 1 1 2 2 2 0 Rifin Saf_2TM PF18303.1 KKK24301.1 - 0.068 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 SAVED-fused 2TM effector domain Utp14 PF04615.13 KKK24301.1 - 0.45 9.0 11.7 0.63 8.5 11.7 1.3 1 0 0 1 1 1 0 Utp14 protein Gemini_mov PF01708.16 KKK24301.1 - 0.69 9.7 0.0 0.69 9.7 0.0 2.4 2 1 0 2 2 2 0 Geminivirus putative movement protein Macoilin PF09726.9 KKK24301.1 - 0.81 8.2 18.6 1.6 7.2 18.6 1.5 1 0 0 1 1 1 0 Macoilin family Endomucin PF07010.12 KKK24301.1 - 5 7.0 66.2 0.58 10.1 62.0 1.5 2 0 0 2 2 2 0 Endomucin Ndc1_Nup PF09531.10 KKK24301.1 - 7 5.2 18.4 10 4.7 18.4 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup MFS_1 PF07690.16 KKK24302.1 - 4.8e-43 147.4 30.6 4.8e-43 147.4 30.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KKK24302.1 - 1.9e-13 50.1 6.2 1.9e-13 50.1 6.2 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter DNA_primase_S PF01896.19 KKK24305.1 - 3.2e-61 206.4 0.0 4.4e-61 206.0 0.0 1.2 1 0 0 1 1 1 1 DNA primase small subunit COesterase PF00135.28 KKK24306.1 - 1.4e-59 202.3 0.0 4.6e-59 200.6 0.0 1.8 1 1 0 2 2 2 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KKK24306.1 - 1.4e-11 44.7 0.1 5.2e-11 42.8 0.0 1.9 2 1 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KKK24306.1 - 0.046 13.2 0.0 0.086 12.3 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Fig1 PF12351.8 KKK24307.1 - 7e-60 202.2 6.5 7e-60 202.2 6.5 2.0 2 0 0 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 SUR7 PF06687.12 KKK24307.1 - 8.1e-08 32.1 9.1 1.2e-07 31.5 9.1 1.3 1 0 0 1 1 1 1 SUR7/PalI family SAM_adeno_trans PF01887.16 KKK24307.1 - 0.028 13.8 0.2 0.043 13.3 0.2 1.2 1 0 0 1 1 1 0 S-adenosyl-l-methionine hydroxide adenosyltransferase DUF898 PF05987.13 KKK24307.1 - 0.045 12.8 10.9 0.0073 15.4 6.4 1.7 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF898) ODV-E18 PF10717.9 KKK24307.1 - 0.061 13.2 1.0 0.061 13.2 1.0 3.1 3 1 1 4 4 4 0 Occlusion-derived virus envelope protein ODV-E18 DUF2207 PF09972.9 KKK24307.1 - 0.16 10.7 13.4 0.38 9.5 2.0 2.3 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) Amastin PF07344.11 KKK24307.1 - 3 7.7 9.0 0.53 10.1 4.6 1.9 2 0 0 2 2 2 0 Amastin surface glycoprotein XPG_I PF00867.18 KKK24308.1 - 6.8e-24 84.0 0.2 1.6e-23 82.9 0.2 1.7 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 KKK24308.1 - 2.3e-23 82.6 0.0 5.9e-23 81.3 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.7 KKK24308.1 - 1.5e-05 24.6 0.1 2.5e-05 23.9 0.1 1.4 1 0 0 1 1 1 1 XPG domain containing TPR_2 PF07719.17 KKK24308.1 - 0.14 12.3 0.0 0.41 10.9 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat HTH_13 PF11972.8 KKK24308.1 - 0.16 12.1 0.2 9.3 6.4 0.0 2.8 3 0 0 3 3 3 0 HTH DNA binding domain 5_3_exonuc PF01367.20 KKK24308.1 - 0.17 12.5 0.0 0.48 11.1 0.0 1.7 1 0 0 1 1 1 0 5'-3' exonuclease, C-terminal SAM fold MAM33 PF02330.16 KKK24309.1 - 2.9e-71 239.8 1.6 4.7e-71 239.1 1.6 1.4 1 0 0 1 1 1 1 Mitochondrial glycoprotein Tma16 PF11176.8 KKK24309.1 - 2.6e-46 157.1 0.0 6.2e-46 155.9 0.0 1.6 1 0 0 1 1 1 1 Translation machinery-associated protein 16 NPV_P10 PF05531.12 KKK24309.1 - 0.11 13.0 0.2 0.42 11.1 0.1 2.0 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Thionin PF00321.17 KKK24309.1 - 0.22 12.0 0.0 0.39 11.2 0.0 1.3 1 0 0 1 1 1 0 Plant thionin Cactin_mid PF10312.9 KKK24311.1 - 4.9e-63 212.5 3.3 7.9e-63 211.8 3.3 1.3 1 0 0 1 1 1 1 Conserved mid region of cactin CactinC_cactus PF09732.9 KKK24311.1 - 7.1e-59 197.2 6.0 3.5e-58 195.0 6.4 1.8 2 0 0 2 2 2 1 Cactus-binding C-terminus of cactin protein DUF1087 PF06465.13 KKK24311.1 - 0.018 15.1 0.4 0.065 13.3 0.2 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1087) XLF PF09302.11 KKK24312.1 - 9e-52 175.8 1.4 9e-52 175.8 1.4 1.9 2 0 0 2 2 2 1 XLF-Cernunnos, XRcc4-like factor, NHEJ component Forkhead PF00250.18 KKK24313.1 - 1.7e-21 76.3 0.0 3.3e-21 75.3 0.0 1.4 1 0 0 1 1 1 1 Forkhead domain SKN1 PF03935.15 KKK24335.1 - 5e-229 760.8 2.6 6.1e-229 760.5 2.6 1.1 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) zf-RING_2 PF13639.6 KKK24346.1 - 2e-11 44.0 4.8 3.6e-11 43.2 4.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KKK24346.1 - 9.4e-10 38.1 1.7 1.8e-09 37.2 1.7 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KKK24346.1 - 5.8e-08 32.5 5.4 1.1e-07 31.6 5.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KKK24346.1 - 7.6e-06 25.8 0.9 7.6e-06 25.8 0.9 2.0 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KKK24346.1 - 1.1e-05 25.2 3.6 1.8e-05 24.5 3.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KKK24346.1 - 2.3e-05 24.2 2.5 3.9e-05 23.5 2.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 KKK24346.1 - 0.00015 22.0 4.5 0.00073 19.8 4.5 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 KKK24346.1 - 0.00069 19.4 2.4 0.0011 18.8 2.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KKK24346.1 - 0.0012 18.6 4.3 0.0028 17.5 4.3 1.5 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 TMEM154 PF15102.6 KKK24346.1 - 0.012 15.5 0.5 0.042 13.7 0.0 2.0 2 0 0 2 2 2 0 TMEM154 protein family BPD_transp_1 PF00528.22 KKK24346.1 - 0.049 13.4 0.0 0.069 12.9 0.0 1.2 1 0 0 1 1 1 0 Binding-protein-dependent transport system inner membrane component DUF3377 PF11857.8 KKK24346.1 - 0.051 13.5 0.1 0.11 12.4 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) zf-C3H2C3 PF17122.5 KKK24346.1 - 0.06 13.4 1.3 0.15 12.2 1.3 1.6 1 0 0 1 1 1 0 Zinc-finger DUF4389 PF14333.6 KKK24346.1 - 0.061 13.2 0.5 0.12 12.3 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4389) zf-ANAPC11 PF12861.7 KKK24346.1 - 0.079 13.0 1.1 0.19 11.8 1.1 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger PHD PF00628.29 KKK24346.1 - 0.083 12.8 2.9 0.16 11.9 2.9 1.5 1 0 0 1 1 1 0 PHD-finger Zn_ribbon_17 PF17120.5 KKK24346.1 - 0.26 11.0 2.9 0.49 10.1 2.9 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Orf78 PF06024.12 KKK24346.1 - 0.32 11.3 0.9 0.67 10.3 0.0 1.8 2 0 0 2 2 2 0 Orf78 (ac78) zf-RING-like PF08746.11 KKK24346.1 - 0.41 11.0 2.3 0.88 9.9 2.2 1.6 1 1 0 1 1 1 0 RING-like domain zf-C3HC4_4 PF15227.6 KKK24346.1 - 0.53 10.5 4.7 1.4 9.1 4.7 1.8 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING FRG1 PF06229.12 KKK24347.1 - 6e-57 192.4 0.2 1.1e-56 191.6 0.2 1.4 1 1 0 1 1 1 1 FRG1-like domain FAM199X PF15814.5 KKK24347.1 - 0.4 9.7 6.8 0.067 12.2 3.1 1.5 2 0 0 2 2 2 0 Protein family FAM199X ADH_N PF08240.12 KKK24348.1 - 1.8e-35 121.1 2.5 1.5e-34 118.2 2.5 2.2 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KKK24348.1 - 5.6e-14 52.2 0.0 9.1e-14 51.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KKK24348.1 - 1.4e-11 44.3 0.0 2.1e-11 43.7 0.0 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 KKK24348.1 - 5e-06 27.6 0.0 8.6e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_7 PF13241.6 KKK24348.1 - 0.0033 17.8 0.0 0.0063 16.9 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding FAD_binding_3 PF01494.19 KKK24348.1 - 0.0082 15.4 0.5 0.013 14.7 0.5 1.2 1 0 0 1 1 1 1 FAD binding domain XdhC_C PF13478.6 KKK24348.1 - 0.071 13.6 0.0 0.11 13.0 0.0 1.3 1 0 0 1 1 1 0 XdhC Rossmann domain HECT PF00632.25 KKK24349.1 - 1.7e-74 251.0 0.0 2.1e-74 250.8 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) AJAP1_PANP_C PF15298.6 KKK24350.1 - 0.014 15.6 0.2 0.1 12.8 0.0 2.3 2 0 0 2 2 2 0 AJAP1/PANP C-terminus Ribosomal_L15e PF00827.17 KKK24351.1 - 1.4e-89 298.9 10.7 1.7e-89 298.6 10.7 1.0 1 0 0 1 1 1 1 Ribosomal L15 PSP1 PF04468.12 KKK24352.1 - 5.4e-28 97.1 2.6 9e-28 96.4 2.6 1.4 1 0 0 1 1 1 1 PSP1 C-terminal conserved region Nfu_N PF08712.11 KKK24353.1 - 2.8e-30 104.2 0.1 1e-29 102.4 0.0 2.0 3 0 0 3 3 3 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.17 KKK24353.1 - 9.6e-28 96.1 0.2 1.6e-27 95.4 0.2 1.4 1 0 0 1 1 1 1 NifU-like domain NPR2 PF06218.11 KKK24354.1 - 3.3e-138 461.1 0.1 2.7e-137 458.1 0.1 2.3 1 1 0 1 1 1 1 Nitrogen permease regulator 2 LRR19-TM PF15176.6 KKK24354.1 - 0.42 10.6 6.0 0.94 9.5 6.0 1.5 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain SelP_N PF04592.14 KKK24354.1 - 0.89 8.9 11.0 1.5 8.1 11.0 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Ada3 PF10198.9 KKK24355.1 - 7.1e-51 171.8 0.2 7.1e-51 171.8 0.2 2.1 2 1 0 2 2 2 1 Histone acetyltransferases subunit 3 tRNA-synt_2 PF00152.20 KKK24356.1 - 5.7e-67 226.0 0.0 6.7e-67 225.8 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.20 KKK24356.1 - 1.4e-07 31.2 0.1 0.00013 21.6 0.0 2.4 3 0 0 3 3 3 2 tRNA synthetases class II core domain (F) tRNA_anti-codon PF01336.25 KKK24356.1 - 0.0026 17.7 0.0 0.0049 16.8 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain zf-Tim10_DDP PF02953.15 KKK24357.1 - 2.9e-23 81.3 0.8 3.5e-23 81.0 0.8 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger ABC_membrane_2 PF06472.15 KKK24358.1 - 5.3e-86 288.4 0.0 9.1e-86 287.6 0.0 1.4 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 Clr2 PF10383.9 KKK24358.1 - 1.5e-30 106.9 0.0 2.8e-30 106.0 0.0 1.5 1 0 0 1 1 1 1 Transcription-silencing protein Clr2 Clr2_transil PF16761.5 KKK24358.1 - 3.7e-18 66.1 0.1 8.3e-18 65.0 0.1 1.6 1 0 0 1 1 1 1 Transcription-silencing protein, cryptic loci regulator Clr2 ABC_tran PF00005.27 KKK24358.1 - 2.8e-12 47.3 0.0 5.8e-12 46.3 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_23 PF13476.6 KKK24358.1 - 0.0066 17.0 1.2 1.5 9.2 0.0 2.6 3 0 0 3 3 3 1 AAA domain RuvB_N PF05496.12 KKK24358.1 - 0.038 13.7 0.0 0.11 12.2 0.0 1.8 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KKK24358.1 - 0.12 12.7 0.1 0.3 11.5 0.1 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 KKK24358.1 - 0.13 12.1 0.0 0.5 10.2 0.0 2.0 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA PF00004.29 KKK24358.1 - 0.13 12.6 0.5 0.31 11.4 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Rx_N PF18052.1 KKK24358.1 - 0.5 10.7 1.8 54 4.2 0.0 2.7 2 0 0 2 2 2 0 Rx N-terminal domain 2OG-FeII_Oxy PF03171.20 KKK24359.1 - 0.00027 21.4 0.0 0.00051 20.5 0.0 1.7 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily NAD_binding_1 PF00175.21 KKK24360.1 - 2.5e-34 118.2 0.0 4e-34 117.6 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KKK24360.1 - 9.2e-22 77.3 0.0 1.9e-21 76.3 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 KKK24360.1 - 3e-08 33.9 0.0 0.00047 20.3 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain B12D PF06522.11 KKK24360.1 - 0.069 12.9 0.0 8.9 6.2 0.0 2.4 2 0 0 2 2 2 0 NADH-ubiquinone reductase complex 1 MLRQ subunit Ribosomal_L18A PF01775.17 KKK24361.1 - 5.1e-55 184.7 0.2 6.4e-55 184.4 0.2 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A PCI PF01399.27 KKK24362.1 - 1.5e-09 38.3 0.0 3.3e-09 37.2 0.0 1.6 1 0 0 1 1 1 1 PCI domain DUF433 PF04255.14 KKK24362.1 - 0.024 14.5 0.0 0.057 13.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF433) ARID PF01388.21 KKK24362.1 - 0.15 12.7 0.0 0.74 10.5 0.0 2.1 2 0 0 2 2 2 0 ARID/BRIGHT DNA binding domain BTB PF00651.31 KKK24363.1 - 1.9e-05 24.8 0.1 0.00018 21.7 0.0 2.4 3 0 0 3 3 3 1 BTB/POZ domain Lactamase_B_2 PF12706.7 KKK24365.1 - 1.5e-07 31.1 0.0 3.3e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DRMBL PF07522.14 KKK24365.1 - 0.004 17.3 0.1 0.015 15.5 0.0 2.0 2 0 0 2 2 2 1 DNA repair metallo-beta-lactamase Lactamase_B PF00753.27 KKK24365.1 - 0.034 14.1 0.0 0.13 12.2 0.0 2.0 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily Amidohydro_1 PF01979.20 KKK24366.1 - 2.7e-75 253.8 1.9 4.1e-75 253.2 1.9 1.2 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.20 KKK24366.1 - 7e-57 191.0 0.7 1.4e-56 190.0 0.7 1.5 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Urease_beta PF00699.20 KKK24366.1 - 1.9e-41 140.0 0.2 5.2e-41 138.6 0.0 1.8 2 0 0 2 2 2 1 Urease beta subunit Urease_gamma PF00547.18 KKK24366.1 - 1.8e-38 130.8 0.4 7e-38 128.9 0.1 2.2 3 0 0 3 3 3 1 Urease, gamma subunit Amidohydro_3 PF07969.11 KKK24366.1 - 1.6e-09 37.7 0.2 1e-06 28.5 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_2 PF04909.14 KKK24366.1 - 0.12 12.2 0.0 0.98 9.1 0.0 2.2 2 0 0 2 2 2 0 Amidohydrolase HMG_box PF00505.19 KKK24367.1 - 1.3e-10 41.5 1.7 1.3e-10 41.5 1.7 2.6 3 0 0 3 3 3 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KKK24367.1 - 0.00024 21.6 0.5 0.00024 21.6 0.5 3.1 3 1 2 5 5 5 1 HMG-box domain CDC45 PF02724.14 KKK24367.1 - 1 7.6 20.5 1.6 6.9 20.5 1.3 1 0 0 1 1 1 0 CDC45-like protein GREB1 PF15782.5 KKK24367.1 - 2 5.4 5.1 2.9 4.9 5.1 1.3 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer GEN1_C PF18380.1 KKK24367.1 - 6.9 7.6 0.0 6.9 7.6 0.0 3.5 2 1 0 2 2 2 0 Holliday junction resolvase Gen1 C-terminal domain Plasmodium_Vir PF05795.11 KKK24367.1 - 7.7 5.8 11.5 13 5.1 11.5 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein CLTH PF10607.9 KKK24368.1 - 4.6e-34 117.4 0.2 2.8e-33 114.9 0.0 2.2 2 1 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.6 KKK24368.1 - 3.7e-07 30.1 1.7 8.4e-07 28.9 1.7 1.7 1 0 0 1 1 1 1 RING-type zinc-finger Rtf2 PF04641.12 KKK24368.1 - 0.00019 20.9 0.3 0.00019 20.9 0.3 2.3 3 0 0 3 3 3 1 Rtf2 RING-finger zf-RING_5 PF14634.6 KKK24368.1 - 0.0013 18.7 2.0 0.0025 17.8 2.0 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 KKK24368.1 - 0.0014 18.9 2.7 0.0027 18.0 2.7 1.5 1 0 0 1 1 1 1 Ring finger domain INTS5_N PF14837.6 KKK24368.1 - 0.014 15.0 0.4 1.3 8.6 0.0 3.0 2 1 1 3 3 3 0 Integrator complex subunit 5 N-terminus FAP206 PF12018.8 KKK24368.1 - 0.025 14.1 0.5 0.052 13.0 0.5 1.5 1 0 0 1 1 1 0 Domain of unknown function Prok-RING_4 PF14447.6 KKK24368.1 - 0.031 14.1 2.9 0.066 13.1 2.9 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 KKK24368.1 - 0.065 13.1 3.8 0.16 11.8 3.8 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KKK24368.1 - 0.1 12.5 2.4 0.19 11.6 2.4 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF4047 PF13256.6 KKK24368.1 - 0.13 12.5 0.2 0.26 11.5 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4047) zf-C3HC4 PF00097.25 KKK24368.1 - 0.17 11.8 4.0 0.34 10.8 4.0 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) V_ATPase_I PF01496.19 KKK24368.1 - 0.2 9.6 2.6 0.24 9.3 2.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family zf-C3HC4_4 PF15227.6 KKK24368.1 - 0.29 11.3 3.0 0.63 10.3 3.0 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING PIN_8 PF18476.1 KKK24368.1 - 4.6 7.0 7.1 0.86 9.4 1.6 2.1 1 1 0 2 2 2 0 PIN like domain FlaC_arch PF05377.11 KKK24369.1 - 0.085 13.3 1.2 0.3 11.5 0.1 2.3 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) PG_binding_1 PF01471.18 KKK24369.1 - 0.16 12.2 0.0 8.1 6.7 0.0 3.1 3 0 0 3 3 3 0 Putative peptidoglycan binding domain DUF2730 PF10805.8 KKK24369.1 - 0.16 12.1 0.2 0.43 10.7 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) HMMR_N PF15905.5 KKK24369.1 - 0.45 9.9 4.5 2.4 7.5 0.1 2.4 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal HrpB7 PF09486.10 KKK24369.1 - 1 9.7 4.8 0.18 12.2 0.2 1.9 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) zf-HIT PF04438.16 KKK24371.1 - 2e-09 37.2 7.4 3.3e-09 36.5 7.4 1.4 1 0 0 1 1 1 1 HIT zinc finger PolC_DP2 PF03833.13 KKK24371.1 - 0.35 8.7 1.1 0.32 8.8 1.1 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 zf-B_box PF00643.24 KKK24371.1 - 1.1 9.5 7.8 2.1 8.6 7.8 1.4 1 0 0 1 1 1 0 B-box zinc finger ERG2_Sigma1R PF04622.12 KKK24372.1 - 1.4e-71 240.2 0.1 1.2e-70 237.1 0.1 2.1 1 1 0 1 1 1 1 ERG2 and Sigma1 receptor like protein ATP_bind_3 PF01171.20 KKK24372.1 - 5.3e-18 65.4 0.0 1e-17 64.5 0.0 1.5 1 0 0 1 1 1 1 PP-loop family zn-ribbon_14 PF16503.5 KKK24372.1 - 1.1e-17 63.2 3.7 1.1e-17 63.2 3.7 3.0 4 0 0 4 4 4 1 Zinc-ribbon RecR PF02132.15 KKK24372.1 - 0.0071 15.9 1.1 0.0071 15.9 1.1 2.5 3 0 0 3 3 3 1 RecR protein RasGEF PF00617.19 KKK24373.1 - 1.2e-44 152.6 0.3 2.6e-44 151.5 0.1 1.7 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 KKK24373.1 - 6e-15 55.4 0.5 1.5e-14 54.1 0.5 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif Complex1_LYR_2 PF13233.6 KKK24373.1 - 3.4e-13 50.1 0.0 1.1e-12 48.5 0.0 1.9 1 0 0 1 1 1 1 Complex1_LYR-like Ras PF00071.22 KKK24373.1 - 0.005 16.5 0.0 0.01 15.4 0.0 1.5 1 0 0 1 1 1 1 Ras family Cadherin_pro PF08758.11 KKK24373.1 - 0.031 14.4 0.0 0.093 12.9 0.0 1.7 2 0 0 2 2 2 0 Cadherin prodomain like Cyclin_N PF00134.23 KKK24374.1 - 2.5e-12 46.7 0.0 4.7e-12 45.8 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 KKK24374.1 - 3.2e-07 30.8 0.1 1.1e-06 29.1 0.0 1.9 2 0 0 2 2 2 1 Cyclin Glyco_hydro_12 PF01670.16 KKK24375.1 - 7.3e-46 156.8 7.1 8.5e-46 156.6 7.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 Acetyltransf_8 PF13523.6 KKK24376.1 - 8.4e-45 152.0 0.0 1.3e-44 151.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain OCD_Mu_crystall PF02423.15 KKK24377.1 - 2.4e-10 39.9 0.0 3.4e-09 36.1 0.0 2.8 2 1 0 2 2 2 1 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.20 KKK24377.1 - 1.1e-07 32.0 0.0 6.3e-06 26.3 0.0 2.6 2 1 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase GFO_IDH_MocA PF01408.22 KKK24377.1 - 0.14 13.0 0.0 0.3 11.9 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold DASH_Dad2 PF08654.10 KKK24393.1 - 1.7e-34 118.2 2.1 2.4e-34 117.7 2.1 1.2 1 0 0 1 1 1 1 DASH complex subunit Dad2 NPV_P10 PF05531.12 KKK24393.1 - 0.00058 20.3 3.2 0.36 11.3 0.7 2.1 2 0 0 2 2 2 2 Nucleopolyhedrovirus P10 protein SLX9 PF15341.6 KKK24393.1 - 0.0028 18.1 3.2 0.0036 17.7 3.2 1.2 1 0 0 1 1 1 1 Ribosome biogenesis protein SLX9 Seryl_tRNA_N PF02403.22 KKK24393.1 - 0.009 16.2 0.8 0.009 16.2 0.8 1.8 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain DASH_Duo1 PF08651.10 KKK24393.1 - 0.019 14.7 0.5 0.035 13.9 0.5 1.4 1 0 0 1 1 1 0 DASH complex subunit Duo1 DUF1664 PF07889.12 KKK24393.1 - 0.029 14.4 0.1 0.038 14.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Fmp27_WPPW PF10359.9 KKK24393.1 - 0.086 11.7 4.4 0.096 11.5 4.4 1.0 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain ECM11 PF15463.6 KKK24393.1 - 0.11 13.1 2.5 6.5 7.3 0.1 2.3 2 0 0 2 2 2 0 Extracellular mutant protein 11 bZIP_1 PF00170.21 KKK24393.1 - 0.57 10.3 6.3 0.099 12.7 2.5 1.8 2 1 0 2 2 2 0 bZIP transcription factor ZapB PF06005.12 KKK24393.1 - 0.6 10.6 6.2 0.82 10.2 4.8 2.1 1 1 0 1 1 1 0 Cell division protein ZapB Shugoshin_N PF07558.11 KKK24394.1 - 5.1e-19 67.9 4.6 1.1e-18 66.8 4.6 1.6 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region Shugoshin_C PF07557.11 KKK24394.1 - 1.3e-11 44.1 3.2 5.4e-11 42.1 3.2 2.2 1 0 0 1 1 1 1 Shugoshin C terminus ISET-FN3_linker PF16625.5 KKK24394.1 - 4.5 7.9 7.7 1.7 9.3 0.2 3.4 3 0 0 3 3 3 0 Unstructured linking region I-set and fnIII on Brother of CDO bZIP_2 PF07716.15 KKK24394.1 - 7.7 6.7 9.2 0.12 12.5 0.5 2.6 2 0 0 2 2 2 0 Basic region leucine zipper p450 PF00067.22 KKK24395.1 - 1.6e-67 228.2 0.0 1.9e-67 228.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Ecl1 PF12855.7 KKK24396.1 - 2.4e-11 45.1 17.5 3.9e-11 44.4 17.5 1.3 1 1 0 1 1 1 1 ECL1/2/3 zinc binding proteins PPI_Ypi1 PF07491.11 KKK24397.1 - 2.3e-23 81.8 8.3 2.3e-23 81.8 8.3 2.5 2 1 0 2 2 2 1 Protein phosphatase inhibitor TFIIF_alpha PF05793.12 KKK24397.1 - 0.019 13.6 10.4 0.019 13.6 10.4 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Neur_chan_memb PF02932.16 KKK24397.1 - 0.77 9.8 3.4 0.79 9.7 3.4 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CDC45 PF02724.14 KKK24397.1 - 2.1 6.5 8.5 2.2 6.5 8.5 1.0 1 0 0 1 1 1 0 CDC45-like protein CRM1_C PF08767.11 KKK24398.1 - 3.4e-139 463.5 11.2 3.4e-139 463.5 11.2 2.8 2 1 0 2 2 2 1 CRM1 C terminal Xpo1 PF08389.12 KKK24398.1 - 2.4e-42 144.5 10.3 1.5e-41 141.9 6.4 3.5 2 1 1 3 3 3 1 Exportin 1-like protein CRM1_repeat_2 PF18784.1 KKK24398.1 - 4e-34 116.1 3.9 2.2e-33 113.7 3.9 2.4 2 0 0 2 2 2 1 CRM1 / Exportin repeat 2 CRM1_repeat_3 PF18787.1 KKK24398.1 - 4.7e-29 100.2 5.2 6.9e-29 99.7 0.7 3.1 3 0 0 3 3 3 1 CRM1 / Exportin repeat 3 CRM1_repeat PF18777.1 KKK24398.1 - 8.9e-20 69.9 1.1 2.1e-19 68.7 1.1 1.7 1 0 0 1 1 1 1 Chromosome region maintenance or exportin repeat IBN_N PF03810.19 KKK24398.1 - 2.8e-12 46.4 0.1 1.1e-11 44.4 0.1 2.2 1 0 0 1 1 1 1 Importin-beta N-terminal domain DUF3385 PF11865.8 KKK24398.1 - 0.0063 16.4 1.8 0.37 10.7 0.0 4.1 5 0 0 5 5 5 1 Domain of unknown function (DUF3385) Hemocyanin_M PF00372.19 KKK24398.1 - 0.033 13.4 0.0 0.084 12.0 0.0 1.6 1 0 0 1 1 1 0 Hemocyanin, copper containing domain DRE2_N PF16803.5 KKK24398.1 - 0.049 13.9 0.0 0.32 11.2 0.0 2.4 2 0 0 2 2 2 0 Fe-S cluster assembly protein DRE2 N-terminus HD_assoc PF13286.6 KKK24398.1 - 0.17 12.4 1.9 26 5.4 0.1 3.8 4 0 0 4 4 4 0 Phosphohydrolase-associated domain DAO PF01266.24 KKK24399.1 - 2.9e-50 171.8 0.0 4.5e-50 171.2 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO_C PF16901.5 KKK24399.1 - 1.1e-45 154.6 0.1 1.9e-45 153.8 0.1 1.4 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase Aa_trans PF01490.18 KKK24399.1 - 1.8e-28 99.4 21.3 2.4e-28 99.0 21.3 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein FAD_binding_2 PF00890.24 KKK24399.1 - 1.1e-09 37.9 0.1 2.2e-09 36.9 0.1 1.4 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KKK24399.1 - 0.00098 18.4 0.0 0.0029 16.9 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KKK24399.1 - 0.0017 17.8 0.5 0.0063 15.9 0.3 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KKK24399.1 - 0.0026 17.9 0.2 0.0076 16.5 0.2 1.8 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KKK24399.1 - 0.0035 16.6 0.1 0.0073 15.6 0.1 1.4 1 0 0 1 1 1 1 Thi4 family 3HCDH_N PF02737.18 KKK24399.1 - 0.0043 17.0 0.2 0.0076 16.2 0.2 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.22 KKK24399.1 - 0.0096 15.0 0.1 0.051 12.7 0.1 1.9 2 0 0 2 2 2 1 Glucose inhibited division protein A HI0933_like PF03486.14 KKK24399.1 - 0.011 14.5 0.4 0.016 13.9 0.4 1.2 1 0 0 1 1 1 0 HI0933-like protein Trp_Tyr_perm PF03222.13 KKK24399.1 - 0.017 14.2 16.4 0.024 13.7 16.4 1.2 1 0 0 1 1 1 0 Tryptophan/tyrosine permease family Pyr_redox_3 PF13738.6 KKK24399.1 - 0.022 14.0 0.0 0.076 12.3 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Sacchrp_dh_NADP PF03435.18 KKK24399.1 - 0.13 12.5 0.0 0.27 11.5 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain FAD_binding_3 PF01494.19 KKK24399.1 - 0.14 11.4 0.1 0.46 9.7 0.0 1.9 2 1 0 2 2 2 0 FAD binding domain Pyr_redox PF00070.27 KKK24399.1 - 0.16 12.5 0.2 0.49 11.0 0.2 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Sugar_tr PF00083.24 KKK24400.1 - 2.2e-90 303.7 26.5 2.7e-90 303.4 26.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKK24400.1 - 8.8e-17 61.1 15.3 8.8e-17 61.1 15.3 2.2 1 1 0 2 2 2 1 Major Facilitator Superfamily Zn_clus PF00172.18 KKK24401.1 - 7.8e-10 38.7 8.2 1.6e-09 37.8 8.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KKK24401.1 - 0.014 14.4 0.0 0.052 12.6 0.0 2.0 2 1 0 2 2 2 0 Fungal specific transcription factor domain Sulfatase PF00884.23 KKK24402.1 - 4.8e-69 233.1 0.0 6e-69 232.8 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 KKK24402.1 - 0.0012 18.5 0.0 0.35 10.4 0.0 2.2 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 KKK24402.1 - 0.0031 16.2 0.0 0.0042 15.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF229) DUF4976 PF16347.5 KKK24402.1 - 0.0042 17.3 0.0 0.011 16.0 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4976) Sulfatase_C PF14707.6 KKK24402.1 - 0.016 16.0 0.1 0.25 12.1 0.1 2.3 1 1 0 1 1 1 0 C-terminal region of aryl-sulfatase Ribosomal_S26e PF01283.19 KKK24406.1 - 8.8e-13 48.6 0.2 9.3e-13 48.6 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e Q_salvage PF10343.9 KKK24406.1 - 0.02 14.5 0.0 0.02 14.5 0.0 1.0 1 0 0 1 1 1 0 Potential Queuosine, Q, salvage protein family Thioredoxin PF00085.20 KKK24412.1 - 4.7e-61 203.2 3.7 6.6e-31 106.3 0.2 4.4 4 1 0 4 4 4 3 Thioredoxin Thioredoxin_6 PF13848.6 KKK24412.1 - 5.1e-47 160.2 0.8 1.5e-36 126.0 0.2 3.4 2 1 1 3 3 3 2 Thioredoxin-like domain Calsequestrin PF01216.17 KKK24412.1 - 5e-11 42.3 1.7 1.7e-10 40.5 1.7 1.8 1 1 0 1 1 1 1 Calsequestrin Thioredoxin_8 PF13905.6 KKK24412.1 - 7e-08 32.7 0.0 0.011 16.0 0.0 3.3 3 0 0 3 3 3 2 Thioredoxin-like Thioredoxin_7 PF13899.6 KKK24412.1 - 1.3e-06 28.5 0.0 0.051 13.8 0.0 2.8 2 0 0 2 2 2 2 Thioredoxin-like OST3_OST6 PF04756.13 KKK24412.1 - 1.4e-06 27.9 0.3 0.0047 16.3 0.0 3.3 2 1 1 3 3 3 2 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 KKK24412.1 - 2.1e-06 27.7 1.2 0.012 15.6 0.1 2.9 3 0 0 3 3 3 2 AhpC/TSA family Thioredoxin_2 PF13098.6 KKK24412.1 - 3.8e-06 27.3 1.4 0.11 12.9 0.1 3.4 3 1 0 3 3 3 2 Thioredoxin-like domain Redoxin PF08534.10 KKK24412.1 - 1.3e-05 25.0 2.2 0.79 9.4 0.0 3.4 3 0 0 3 3 3 2 Redoxin Glycos_trans_3N PF02885.17 KKK24412.1 - 0.04 13.8 0.0 0.13 12.1 0.0 1.9 1 0 0 1 1 1 0 Glycosyl transferase family, helical bundle domain UDG PF03167.19 KKK24413.1 - 1.3e-21 77.2 0.1 2.2e-21 76.4 0.1 1.3 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Med14 PF08638.11 KKK24414.1 - 1.2e-67 227.1 0.0 2e-67 226.3 0.0 1.4 1 0 0 1 1 1 1 Mediator complex subunit MED14 ATG22 PF11700.8 KKK24415.1 - 2.5e-212 705.7 15.7 2.8e-212 705.6 15.7 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.16 KKK24415.1 - 1.2e-11 44.2 39.7 4.3e-11 42.3 12.0 3.1 3 0 0 3 3 3 3 Major Facilitator Superfamily Mfp-3 PF04202.13 KKK24415.1 - 0.074 13.4 0.1 15 6.1 0.3 2.6 2 0 0 2 2 2 0 Foot protein 3 SHNi-TPR PF10516.9 KKK24416.1 - 1.2e-17 63.0 1.9 1.6e-16 59.5 0.2 2.8 2 0 0 2 2 2 1 SHNi-TPR TPR_12 PF13424.6 KKK24416.1 - 6.4e-06 26.4 8.1 0.013 15.7 1.9 3.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 KKK24416.1 - 0.0019 17.9 2.4 0.44 10.4 1.2 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat CCDC-167 PF15188.6 KKK24416.1 - 0.013 15.9 1.5 0.013 15.9 1.5 2.0 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 TPR_10 PF13374.6 KKK24416.1 - 0.02 14.8 3.9 5.8 6.9 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 KKK24416.1 - 0.034 13.8 7.1 11 5.7 0.0 4.3 5 0 0 5 5 5 0 TPR repeat TPR_8 PF13181.6 KKK24416.1 - 0.05 13.8 5.7 4.4 7.8 1.6 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat MIT PF04212.18 KKK24416.1 - 0.059 13.5 4.6 0.05 13.7 1.7 2.4 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain TetR_C_32 PF09209.11 KKK24416.1 - 0.11 12.4 0.0 0.96 9.4 0.0 2.2 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain TPR_2 PF07719.17 KKK24416.1 - 0.23 11.7 11.9 3 8.2 1.7 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.6 KKK24416.1 - 0.45 11.1 5.8 1.2 9.7 2.7 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 KKK24416.1 - 0.78 10.4 6.8 21 5.9 0.1 3.0 2 1 0 2 2 2 0 Tetratricopeptide repeat DNA_pol_E_B PF04042.16 KKK24417.1 - 1e-51 175.3 0.0 1.4e-51 174.9 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DWNN PF08783.11 KKK24418.1 - 6.4e-34 116.1 0.5 1.2e-33 115.2 0.1 1.7 2 0 0 2 2 2 1 DWNN domain zf-CCHC_2 PF13696.6 KKK24418.1 - 2.4e-08 33.6 5.0 6.6e-08 32.2 5.0 1.8 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 KKK24418.1 - 0.00087 19.3 2.4 0.0042 17.1 0.7 2.5 2 0 0 2 2 2 1 Zinc knuckle zf-C3HC4_2 PF13923.6 KKK24418.1 - 0.0034 17.2 8.6 0.0071 16.2 8.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) CpXC PF14353.6 KKK24418.1 - 0.051 13.6 0.1 0.12 12.4 0.1 1.6 1 0 0 1 1 1 0 CpXC protein zf-Nse PF11789.8 KKK24418.1 - 0.21 11.4 3.7 0.42 10.5 3.7 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_2 PF13639.6 KKK24418.1 - 0.35 11.2 6.3 0.77 10.1 6.3 1.6 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4 PF00097.25 KKK24418.1 - 2.3 8.2 8.7 5 7.1 8.7 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KKK24418.1 - 4.2 7.4 11.4 0.3 11.1 5.2 2.1 2 0 0 2 2 2 0 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KKK24418.1 - 8.2 6.7 9.6 22 5.3 9.6 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Yippee-Mis18 PF03226.14 KKK24419.1 - 1.1e-24 86.6 0.1 1.5e-24 86.2 0.1 1.2 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RIG-I_C-RD PF11648.8 KKK24419.1 - 0.012 15.9 0.5 0.32 11.2 0.0 2.1 2 0 0 2 2 2 0 C-terminal domain of RIG-I Transp_Tc5_C PF04236.15 KKK24419.1 - 0.025 14.9 0.4 4.6 7.7 0.2 2.4 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain zf-ribbon_3 PF13248.6 KKK24419.1 - 0.058 12.8 0.1 0.058 12.8 0.1 1.9 2 0 0 2 2 2 0 zinc-ribbon domain Lar_restr_allev PF14354.6 KKK24419.1 - 0.11 12.9 0.1 27 5.3 0.0 2.6 3 0 0 3 3 3 0 Restriction alleviation protein Lar dCMP_cyt_deam_1 PF00383.23 KKK24420.1 - 8.8e-28 96.1 1.5 1.4e-27 95.5 1.5 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KKK24420.1 - 1.7e-10 40.8 0.2 3.2e-10 39.9 0.2 1.4 1 0 0 1 1 1 1 MafB19-like deaminase AAA_18 PF13238.6 KKK24420.1 - 0.008 16.7 0.0 0.03 14.8 0.0 1.9 2 1 0 2 2 2 1 AAA domain CoaE PF01121.20 KKK24420.1 - 0.028 14.1 0.0 0.052 13.2 0.0 1.4 1 0 0 1 1 1 0 Dephospho-CoA kinase His_biosynth PF00977.21 KKK24421.1 - 1.1e-48 165.7 0.8 4.4e-48 163.7 0.8 2.0 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.28 KKK24421.1 - 1.7e-23 83.4 0.0 3.2e-23 82.5 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I SNO PF01174.19 KKK24421.1 - 9.6e-12 45.1 0.0 4.7e-09 36.4 0.0 2.2 2 0 0 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.14 KKK24421.1 - 1.2e-07 31.6 0.0 3e-07 30.2 0.0 1.7 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_C26 PF07722.13 KKK24421.1 - 0.0047 16.7 0.0 0.014 15.1 0.0 1.8 1 1 0 1 1 1 1 Peptidase C26 Dus PF01207.17 KKK24421.1 - 0.0089 15.1 0.0 0.021 14.0 0.0 1.5 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) ThiG PF05690.14 KKK24421.1 - 0.22 10.8 2.0 0.17 11.2 0.2 1.7 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG PEP-utilisers_N PF05524.13 KKK24422.1 - 0.016 15.4 0.1 0.069 13.3 0.0 2.0 1 1 1 2 2 2 0 PEP-utilising enzyme, N-terminal Fungal_trans PF04082.18 KKK24423.1 - 1.5e-08 34.0 0.0 4.5e-08 32.5 0.0 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain TRP PF06011.12 KKK24424.1 - 8.1e-142 472.9 10.6 1.1e-141 472.5 10.6 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 KKK24424.1 - 2.5e-39 134.8 0.2 4e-39 134.2 0.2 1.3 1 0 0 1 1 1 1 ML-like domain ETRAMP PF09716.10 KKK24424.1 - 2.3 8.3 0.0 2.3 8.3 0.0 3.2 4 1 0 4 4 4 0 Malarial early transcribed membrane protein (ETRAMP) DUF2663 PF10864.8 KKK24424.1 - 7.3 7.0 9.1 1.8 9.0 0.5 3.1 2 1 2 4 4 4 0 Protein of unknown function (DUF2663) Hep_59 PF07052.11 KKK24425.1 - 3.3e-18 66.4 4.8 1.6e-17 64.2 0.0 3.3 3 1 0 3 3 3 1 Hepatocellular carcinoma-associated antigen 59 Actin PF00022.19 KKK24426.1 - 1.6e-148 494.7 0.0 1.8e-148 494.5 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.13 KKK24426.1 - 0.0033 16.3 0.0 6.8 5.4 0.0 3.0 3 0 0 3 3 3 3 MreB/Mbl protein FtsA PF14450.6 KKK24426.1 - 0.044 14.2 0.0 0.11 13.0 0.0 1.8 2 1 0 2 2 2 0 Cell division protein FtsA DEAD PF00270.29 KKK24427.1 - 8.5e-51 172.2 0.0 2e-50 171.0 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KKK24427.1 - 1.4e-33 115.6 0.5 1.9e-30 105.5 0.1 2.4 2 1 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.15 KKK24427.1 - 1.2e-08 35.2 0.0 3.1e-08 33.8 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KKK24427.1 - 4.8e-06 26.0 0.1 8e-06 25.2 0.1 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase CMS1 PF14617.6 KKK24427.1 - 0.0064 15.9 0.1 0.0064 15.9 0.1 2.3 3 1 0 3 3 3 1 U3-containing 90S pre-ribosomal complex subunit UTP25 PF06862.12 KKK24427.1 - 0.14 10.9 0.2 8.3 5.0 0.0 2.3 2 1 0 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Rep_fac-A_C PF08646.10 KKK24428.1 - 2.7e-57 192.6 1.9 2.2e-55 186.4 0.8 2.3 2 0 0 2 2 2 2 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 KKK24428.1 - 4.1e-37 126.0 0.1 4e-36 122.9 0.2 2.2 2 0 0 2 2 2 1 Replication protein A OB domain Rep-A_N PF04057.12 KKK24428.1 - 8.4e-22 77.1 0.0 2.2e-21 75.7 0.0 1.8 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.25 KKK24428.1 - 3e-13 49.5 0.0 5.7e-09 35.8 0.0 3.7 3 0 0 3 3 3 2 OB-fold nucleic acid binding domain DUF223 PF02721.14 KKK24428.1 - 0.058 13.7 0.0 0.15 12.3 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function DUF223 CDC24_OB3 PF17244.2 KKK24428.1 - 0.061 13.0 1.3 0.23 11.1 0.2 2.3 3 0 0 3 3 3 0 Cell division control protein 24, OB domain 3 OST3_OST6 PF04756.13 KKK24429.1 - 4.1e-69 233.2 0.4 4.6e-69 233.0 0.4 1.0 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family HXXEE PF13787.6 KKK24429.1 - 0.023 15.5 0.9 0.023 15.5 0.9 2.0 1 1 1 2 2 2 0 Protein of unknown function with HXXEE motif Rft-1 PF04506.13 KKK24430.1 - 1.9e-39 135.8 2.9 2.5e-39 135.4 2.9 1.0 1 0 0 1 1 1 1 Rft protein CbiM PF01891.16 KKK24430.1 - 0.028 14.3 3.4 0.043 13.7 3.4 1.3 1 0 0 1 1 1 0 Cobalt uptake substrate-specific transmembrane region Polysacc_synt_C PF14667.6 KKK24430.1 - 0.03 14.4 7.9 0.046 13.8 7.9 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis C-terminal domain DUF1290 PF06947.12 KKK24430.1 - 0.065 13.3 0.5 0.13 12.4 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1290) DUF2070 PF09843.9 KKK24430.1 - 1.7 6.9 7.0 2.1 6.6 7.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) GAS PF13851.6 KKK24431.1 - 0.01 15.2 11.4 0.01 15.2 11.4 3.0 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding DUF4600 PF15372.6 KKK24431.1 - 0.89 10.0 17.1 2.7 8.4 15.5 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4600) CAMSAP_CC1 PF17095.5 KKK24431.1 - 7.9 6.4 11.0 34 4.4 4.9 2.9 1 1 1 2 2 2 0 Spectrin-binding region of Ca2+-Calmodulin OST3_OST6 PF04756.13 KKK24432.1 - 1.2e-24 87.1 0.0 1.8e-24 86.6 0.0 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family ATG7_N PF16420.5 KKK24433.1 - 1.6e-82 277.6 0.0 6.2e-75 252.6 0.0 2.1 2 0 0 2 2 2 2 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus ThiF PF00899.21 KKK24433.1 - 6e-47 160.1 0.0 9.1e-47 159.5 0.0 1.1 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.20 KKK24433.1 - 0.0067 16.5 0.1 0.028 14.5 0.0 1.9 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase ApbA PF02558.16 KKK24433.1 - 0.1 12.2 0.0 0.28 10.8 0.0 1.7 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.19 KKK24433.1 - 0.12 11.7 0.0 0.59 9.5 0.0 1.9 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FtsJ PF01728.19 KKK24434.1 - 8.2e-56 188.9 0.0 9.8e-56 188.6 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_23 PF13489.6 KKK24434.1 - 0.045 13.6 0.0 0.082 12.7 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain UCH PF00443.29 KKK24435.1 - 9.8e-38 130.1 0.0 1.9e-37 129.2 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP_var PF17807.1 KKK24435.1 - 3.7e-26 90.7 2.2 3.3e-25 87.6 0.2 2.7 2 0 0 2 2 2 1 Variant UBP zinc finger zf-UBP PF02148.19 KKK24435.1 - 7e-24 83.9 17.7 2.5e-20 72.6 1.6 3.8 3 2 0 3 3 3 2 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 KKK24435.1 - 3e-18 66.5 0.1 2.9e-16 60.0 0.0 3.3 3 1 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase UBA PF00627.31 KKK24435.1 - 6.3e-17 61.1 1.6 2e-09 37.1 0.1 2.9 3 0 0 3 3 3 2 UBA/TS-N domain UBA_4 PF14555.6 KKK24435.1 - 0.011 15.6 0.0 0.021 14.6 0.0 1.5 1 0 0 1 1 1 0 UBA-like domain TerY_C PF15616.6 KKK24435.1 - 1 9.5 7.7 1.8 8.7 0.1 3.1 3 1 0 3 3 3 0 TerY-C metal binding domain FAD_binding_3 PF01494.19 KKK24442.1 - 3.6e-17 62.6 0.1 2.8e-12 46.5 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 KKK24442.1 - 6.6e-05 22.1 0.2 0.032 13.3 0.0 2.3 2 0 0 2 2 2 2 Lycopene cyclase protein SE PF08491.10 KKK24442.1 - 0.0033 16.5 0.0 0.041 12.9 0.0 2.0 2 0 0 2 2 2 1 Squalene epoxidase DAO PF01266.24 KKK24442.1 - 0.0059 16.2 0.1 1.5 8.3 0.0 2.4 1 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KKK24442.1 - 0.07 13.4 0.0 0.17 12.1 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain SUIM_assoc PF16619.5 KKK24442.1 - 0.077 13.1 2.8 0.14 12.3 2.8 1.3 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 HI0933_like PF03486.14 KKK24442.1 - 0.17 10.5 0.0 0.25 10.0 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein adh_short PF00106.25 KKK24443.1 - 1.5e-28 99.6 0.0 2.1e-28 99.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KKK24443.1 - 4.5e-23 82.0 0.0 8.1e-23 81.2 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KKK24443.1 - 4.7e-07 29.9 0.0 0.00043 20.2 0.0 2.2 2 0 0 2 2 2 2 KR domain Peptidase_S29 PF02907.15 KKK24443.1 - 0.13 12.0 0.3 0.21 11.3 0.3 1.3 1 0 0 1 1 1 0 Hepatitis C virus NS3 protease Zn_clus PF00172.18 KKK24444.1 - 2.4e-06 27.5 8.7 3.5e-06 27.0 8.7 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MGC-24 PF05283.11 KKK24444.1 - 0.26 11.7 2.7 0.13 12.7 0.4 1.6 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin ADH_zinc_N PF00107.26 KKK24445.1 - 8.4e-10 38.7 0.0 1.9e-09 37.6 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KKK24445.1 - 3e-05 25.1 0.0 6.5e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KKK24445.1 - 4.6e-05 23.3 0.6 0.00077 19.3 0.1 2.6 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain AMP-binding PF00501.28 KKK24446.1 - 1.3e-75 254.6 0.2 2.9e-75 253.5 0.1 1.6 2 0 0 2 2 2 1 AMP-binding enzyme ketoacyl-synt PF00109.26 KKK24446.1 - 7.1e-75 251.8 0.0 1.2e-74 251.1 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Condensation PF00668.20 KKK24446.1 - 9.6e-60 202.5 0.0 1.7e-59 201.7 0.0 1.3 1 0 0 1 1 1 1 Condensation domain KR PF08659.10 KKK24446.1 - 3.2e-50 170.5 0.1 1.5e-49 168.4 0.0 2.3 3 0 0 3 3 2 1 KR domain PS-DH PF14765.6 KKK24446.1 - 3.5e-44 151.2 0.0 5.6e-44 150.6 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 KKK24446.1 - 1.5e-43 149.6 0.2 2.9e-43 148.6 0.2 1.5 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KKK24446.1 - 3e-30 104.7 0.0 7.2e-30 103.4 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain NAD_binding_4 PF07993.12 KKK24446.1 - 1e-28 100.2 0.0 3.3e-28 98.6 0.0 1.8 2 0 0 2 2 2 1 Male sterility protein Methyltransf_12 PF08242.12 KKK24446.1 - 1.7e-21 76.8 0.3 5.2e-21 75.2 0.0 2.1 2 0 0 2 2 1 1 Methyltransferase domain PP-binding PF00550.25 KKK24446.1 - 2.5e-17 63.0 0.8 4.2e-07 30.2 0.3 3.4 3 0 0 3 3 3 2 Phosphopantetheine attachment site Methyltransf_25 PF13649.6 KKK24446.1 - 1.2e-13 51.6 0.0 5.2e-13 49.5 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 KKK24446.1 - 1.3e-13 51.3 0.0 4e-13 49.8 0.0 1.8 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_23 PF13489.6 KKK24446.1 - 8e-13 48.5 0.0 1.8e-12 47.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KKK24446.1 - 2e-12 47.6 0.0 8.5e-12 45.6 0.0 2.2 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KKK24446.1 - 2.1e-10 40.6 0.0 7.4e-10 38.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 KKK24446.1 - 7.1e-09 35.3 0.0 1.6e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Epimerase PF01370.21 KKK24446.1 - 3.8e-07 29.8 0.0 6.4e-06 25.8 0.0 2.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family adh_short PF00106.25 KKK24446.1 - 8.4e-07 28.6 0.0 1.5e-05 24.5 0.0 2.7 3 0 0 3 3 3 1 short chain dehydrogenase Thiolase_N PF00108.23 KKK24446.1 - 1.3e-06 27.9 0.2 4.2e-06 26.3 0.1 1.8 2 0 0 2 2 2 1 Thiolase, N-terminal domain NodS PF05401.11 KKK24446.1 - 3.8e-05 23.4 0.0 8.2e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 Nodulation protein S (NodS) RrnaAD PF00398.20 KKK24446.1 - 0.014 14.5 0.0 0.032 13.3 0.0 1.5 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_16 PF10294.9 KKK24446.1 - 0.015 15.0 0.0 0.045 13.5 0.0 1.7 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_33 PF10017.9 KKK24446.1 - 0.02 14.1 0.0 0.041 13.0 0.0 1.4 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent AMP-binding_C PF13193.6 KKK24446.1 - 0.022 15.7 0.0 0.068 14.2 0.0 2.0 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain Methyltransf_28 PF02636.17 KKK24446.1 - 0.053 13.2 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase RTA1 PF04479.13 KKK24447.1 - 2.5e-45 154.7 9.6 2.5e-45 154.7 9.6 2.0 2 1 0 2 2 2 1 RTA1 like protein PHO4 PF01384.20 KKK24447.1 - 0.0086 15.2 2.2 0.0094 15.0 0.0 1.9 2 0 0 2 2 2 1 Phosphate transporter family DUF3382 PF11862.8 KKK24447.1 - 5 7.5 8.1 0.33 11.2 1.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3382) BRI3BP PF14965.6 KKK24447.1 - 6.4 6.3 7.9 1 8.8 0.3 2.3 2 0 0 2 2 2 0 Negative regulator of p53/TP53 MFS_1 PF07690.16 KKK24448.1 - 2.6e-39 135.1 50.6 9.9e-39 133.2 46.6 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KKK24448.1 - 6.8e-12 44.6 18.5 9.2e-12 44.2 18.5 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF4514 PF14986.6 KKK24448.1 - 1.3 9.1 4.2 1.6 8.8 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4514) TPR_1 PF00515.28 KKK24464.1 - 1.3e-40 135.6 25.9 5.8e-07 29.1 0.1 11.5 10 1 1 11 11 11 9 Tetratricopeptide repeat TPR_2 PF07719.17 KKK24464.1 - 3.5e-38 126.7 26.4 7.3e-06 25.7 0.1 10.7 10 0 0 10 10 10 8 Tetratricopeptide repeat TPR_16 PF13432.6 KKK24464.1 - 4.6e-25 88.0 12.9 1.1e-06 29.1 0.2 6.8 6 1 1 7 7 7 6 Tetratricopeptide repeat TPR_8 PF13181.6 KKK24464.1 - 1.2e-23 81.3 18.5 0.00021 21.2 0.0 10.4 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_11 PF13414.6 KKK24464.1 - 2e-19 69.0 25.1 1.9e-06 27.4 0.0 8.4 6 1 2 8 8 8 6 TPR repeat TPR_12 PF13424.6 KKK24464.1 - 5.3e-18 65.1 26.2 0.0007 19.8 2.1 8.3 4 1 4 8 8 8 5 Tetratricopeptide repeat TPR_17 PF13431.6 KKK24464.1 - 2.6e-17 61.8 8.3 0.05 14.0 0.0 8.7 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_9 PF13371.6 KKK24464.1 - 1e-16 60.8 8.3 5.4e-07 29.7 0.2 5.7 3 1 3 6 6 6 4 Tetratricopeptide repeat TPR_19 PF14559.6 KKK24464.1 - 2.5e-13 50.3 22.3 5.8e-05 23.5 0.8 7.2 6 1 1 8 8 7 4 Tetratricopeptide repeat TPR_14 PF13428.6 KKK24464.1 - 2.4e-12 46.5 15.6 0.025 15.4 0.1 8.9 4 2 6 10 10 8 3 Tetratricopeptide repeat TPR_7 PF13176.6 KKK24464.1 - 2.5e-11 42.8 14.8 0.025 14.6 0.1 8.3 7 2 1 8 8 8 3 Tetratricopeptide repeat ANAPC3 PF12895.7 KKK24464.1 - 1.2e-07 31.9 13.5 0.038 14.2 0.0 5.3 3 1 3 6 6 6 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 KKK24464.1 - 3.2e-07 30.0 17.4 0.23 11.4 0.4 8.6 9 0 0 9 9 9 1 Tetratricopeptide repeat SHNi-TPR PF10516.9 KKK24464.1 - 5.8e-06 25.7 11.5 0.069 12.6 0.1 6.3 6 0 0 6 6 6 2 SHNi-TPR TPR_MalT PF17874.1 KKK24464.1 - 1e-05 25.1 6.7 2.6e-05 23.8 3.4 2.8 1 1 1 2 2 2 1 MalT-like TPR region MAS20 PF02064.15 KKK24464.1 - 0.00018 21.6 9.1 0.032 14.3 1.7 4.3 4 1 1 5 5 4 1 MAS20 protein import receptor Sel1 PF08238.12 KKK24464.1 - 0.0022 18.6 3.5 0.9 10.3 0.2 4.0 3 0 0 3 3 3 1 Sel1 repeat ARL6IP6 PF15062.6 KKK24464.1 - 0.0038 17.3 0.1 0.0095 16.0 0.1 1.6 1 0 0 1 1 1 1 Haemopoietic lineage transmembrane helix TPR_4 PF07721.14 KKK24464.1 - 0.013 16.1 0.1 34 5.5 0.0 4.9 5 0 0 5 5 4 0 Tetratricopeptide repeat GPCR_chapero_1 PF11904.8 KKK24464.1 - 0.1 12.0 1.9 0.17 11.3 1.9 1.3 1 0 0 1 1 1 0 GPCR-chaperone SPO22 PF08631.10 KKK24464.1 - 0.11 12.0 3.1 1.5 8.2 0.0 3.4 3 1 1 4 4 4 0 Meiosis protein SPO22/ZIP4 like TPR_6 PF13174.6 KKK24464.1 - 0.11 13.2 25.5 8.8 7.2 0.6 8.5 10 0 0 10 10 8 0 Tetratricopeptide repeat NARP1 PF12569.8 KKK24464.1 - 0.19 10.6 22.3 0.42 9.5 0.3 4.4 3 1 4 7 7 7 0 NMDA receptor-regulated protein 1 ANAPC5 PF12862.7 KKK24464.1 - 0.21 11.7 8.4 17 5.5 0.3 4.5 2 2 1 3 3 3 0 Anaphase-promoting complex subunit 5 Usp PF00582.26 KKK24464.1 - 0.4 11.2 8.6 3.2 8.3 1.7 3.5 4 0 0 4 4 3 0 Universal stress protein family MIT PF04212.18 KKK24464.1 - 6.7 6.9 17.4 37 4.5 0.9 6.4 7 0 0 7 7 6 0 MIT (microtubule interacting and transport) domain FHA PF00498.26 KKK24465.1 - 1.7e-13 50.7 0.2 4.9e-13 49.2 0.0 1.9 2 0 0 2 2 2 1 FHA domain Yop-YscD_cpl PF16697.5 KKK24465.1 - 0.061 13.6 0.0 0.14 12.5 0.0 1.5 1 0 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain Aminotran_4 PF01063.19 KKK24466.1 - 1.1e-37 130.1 0.0 1.3e-37 129.8 0.0 1.0 1 0 0 1 1 1 1 Amino-transferase class IV PRELI PF04707.14 KKK24467.1 - 1.7e-22 80.0 0.0 1.8e-20 73.3 0.0 2.2 2 0 0 2 2 2 2 PRELI-like family An_peroxidase PF03098.15 KKK24468.1 - 3.8e-37 128.1 0.0 1.7e-25 89.7 0.0 3.9 1 1 1 2 2 2 2 Animal haem peroxidase p450 PF00067.22 KKK24468.1 - 5.6e-06 25.4 0.0 0.00093 18.1 0.0 2.2 2 0 0 2 2 2 2 Cytochrome P450 HUN PF08729.10 KKK24484.1 - 4.1e-08 33.1 0.2 1.4e-07 31.4 0.2 1.9 1 0 0 1 1 1 1 HPC2 and ubinuclein domain Roughex PF06020.11 KKK24484.1 - 1.2 8.2 14.6 2.5 7.1 14.6 1.5 1 0 0 1 1 1 0 Drosophila roughex protein Apt1 PF10351.9 KKK24484.1 - 4.6 6.0 11.7 8.4 5.1 11.7 1.4 1 0 0 1 1 1 0 Golgi-body localisation protein domain Glyco_hydro_18 PF00704.28 KKK24485.1 - 3.3e-33 115.8 0.0 3.8e-33 115.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 KKK24485.1 - 1.5e-09 38.2 33.3 2.2e-09 37.6 8.2 3.0 2 1 0 2 2 2 2 Chitin recognition protein VirE1 PF12189.8 KKK24485.1 - 0.15 12.2 0.0 0.27 11.3 0.0 1.3 1 0 0 1 1 1 0 Single-strand DNA-binding protein GARS_C PF02843.16 KKK24486.1 - 0.16 12.2 0.0 0.43 10.9 0.0 1.7 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, C domain Glyco_transf_8 PF01501.20 KKK24487.1 - 2.3e-08 33.9 0.0 2.8e-08 33.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 8 Glyco_transf_24 PF18404.1 KKK24487.1 - 0.016 14.7 0.0 0.018 14.5 0.0 1.1 1 0 0 1 1 1 0 Glucosyltransferase 24 Mannosyl_trans3 PF11051.8 KKK24487.1 - 0.22 10.8 0.0 0.28 10.5 0.0 1.1 1 0 0 1 1 1 0 Mannosyltransferase putative RPAP1_C PF08620.10 KKK24488.1 - 2.5e-24 85.1 0.0 4.4e-24 84.4 0.0 1.4 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.10 KKK24488.1 - 2.3e-16 59.3 6.4 2.3e-16 59.3 6.4 1.7 2 0 0 2 2 2 1 RPAP1-like, N-terminal ASD2 PF08687.11 KKK24488.1 - 0.028 14.0 2.1 0.054 13.0 2.1 1.4 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 ANAPC1 PF12859.7 KKK24489.1 - 1.1e-32 113.3 1.0 4.2e-32 111.4 1.0 2.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 1 PC_rep PF01851.22 KKK24489.1 - 0.34 11.4 0.0 0.34 11.4 0.0 4.2 5 0 0 5 5 5 0 Proteasome/cyclosome repeat MIT PF04212.18 KKK24496.1 - 5.7e-05 23.1 0.3 0.0001 22.3 0.3 1.4 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain Baculo_LEF-11 PF06385.12 KKK24496.1 - 0.016 15.7 0.1 0.03 14.8 0.1 1.4 1 0 0 1 1 1 0 Baculovirus LEF-11 protein TPR_1 PF00515.28 KKK24496.1 - 0.14 12.1 0.1 0.26 11.2 0.1 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat Exo_endo_phos PF03372.23 KKK24497.1 - 3.4e-08 33.3 0.2 6.7e-08 32.3 0.2 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family AAA PF00004.29 KKK24498.1 - 2e-14 54.1 0.0 0.0003 21.2 0.0 3.4 3 0 0 3 3 3 3 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KKK24498.1 - 1.3e-07 32.0 2.6 0.091 13.0 0.0 4.9 3 3 1 4 4 4 2 AAA domain AAA_33 PF13671.6 KKK24498.1 - 5.8e-06 26.5 0.2 0.017 15.3 0.0 4.2 3 3 0 3 3 3 1 AAA domain AAA_18 PF13238.6 KKK24498.1 - 7.1e-06 26.6 0.0 0.92 10.1 0.0 3.6 3 0 0 3 3 3 2 AAA domain Torsin PF06309.11 KKK24498.1 - 9.4e-05 22.5 0.0 0.056 13.5 0.0 2.7 2 0 0 2 2 2 1 Torsin AAA_16 PF13191.6 KKK24498.1 - 0.0014 19.1 0.6 4.6 7.6 0.1 4.0 3 1 0 3 3 3 1 AAA ATPase domain RuvB_N PF05496.12 KKK24498.1 - 0.0016 18.2 0.0 7.7 6.2 0.0 3.5 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KKK24498.1 - 0.0021 18.1 0.2 1.5 8.8 0.0 3.2 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 KKK24498.1 - 0.0026 17.2 0.0 0.32 10.3 0.0 2.8 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_30 PF13604.6 KKK24498.1 - 0.0039 16.9 0.1 0.45 10.2 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.6 KKK24498.1 - 0.023 15.0 0.0 2.8 8.3 0.0 3.5 3 1 1 4 4 4 0 AAA domain AAA_28 PF13521.6 KKK24498.1 - 0.04 14.2 5.5 5.3 7.3 0.0 3.8 4 0 0 4 4 4 0 AAA domain NAD_binding_9 PF13454.6 KKK24498.1 - 0.046 13.7 0.0 0.1 12.6 0.0 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding AAA_24 PF13479.6 KKK24498.1 - 0.088 12.5 0.0 4.6 6.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KKK24498.1 - 0.19 12.2 0.1 8.3 6.9 0.0 3.5 5 1 0 5 5 5 0 RNA helicase AAA_lid_6 PF17866.1 KKK24498.1 - 3.5 7.9 6.2 1.2 9.3 1.1 2.9 3 0 0 3 3 3 0 AAA lid domain Ald_Xan_dh_C2 PF02738.18 KKK24499.1 - 2.7e-203 676.4 0.6 3.7e-203 675.9 0.6 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.21 KKK24499.1 - 1.3e-40 138.9 0.0 2.5e-40 138.0 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase CO_deh_flav_C PF03450.17 KKK24499.1 - 3.8e-32 110.5 0.1 2.5e-31 107.9 0.0 2.4 2 0 0 2 2 2 1 CO dehydrogenase flavoprotein C-terminal domain Ald_Xan_dh_C PF01315.22 KKK24499.1 - 2.6e-28 98.6 0.0 5.9e-28 97.4 0.0 1.7 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2_2 PF01799.20 KKK24499.1 - 3.4e-25 87.9 0.0 8.4e-25 86.6 0.0 1.8 1 0 0 1 1 1 1 [2Fe-2S] binding domain Fer2 PF00111.27 KKK24499.1 - 5.1e-08 32.8 0.0 3e-07 30.3 0.0 2.4 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain tRNA-synt_1c PF00749.21 KKK24501.1 - 5.8e-96 321.1 0.0 8.2e-96 320.6 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 KKK24501.1 - 2.4e-31 109.0 0.0 6.9e-31 107.5 0.0 1.8 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain Btz PF09405.10 KKK24502.1 - 1.5e-33 115.8 3.1 1.5e-33 115.8 3.1 2.1 3 0 0 3 3 3 1 CASC3/Barentsz eIF4AIII binding Ino80_Iec3 PF14612.6 KKK24503.1 - 1.4e-77 261.6 0.1 2.2e-77 260.9 0.1 1.3 1 0 0 1 1 1 1 IEC3 subunit of the Ino80 complex, chromatin re-modelling RRM_1 PF00076.22 KKK24504.1 - 2.3e-21 75.4 0.4 1e-12 47.7 0.1 3.0 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KKK24504.1 - 0.002 18.1 0.1 0.0061 16.5 0.1 1.8 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 KKK24504.1 - 0.0026 17.9 0.0 0.74 10.0 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif IFRD PF05004.13 KKK24505.1 - 1.3e-85 287.2 5.6 1.8e-85 286.7 5.6 1.1 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) Cnd3 PF12719.7 KKK24505.1 - 0.0002 20.7 0.1 0.00044 19.6 0.0 1.7 1 1 0 1 1 1 1 Nuclear condensing complex subunits, C-term domain HEAT_EZ PF13513.6 KKK24505.1 - 0.025 15.1 0.0 1 10.0 0.0 2.8 2 1 0 2 2 2 0 HEAT-like repeat PDDEXK_6 PF04720.12 KKK24505.1 - 0.87 9.5 7.4 0.35 10.8 0.9 2.3 2 0 0 2 2 2 0 PDDEXK-like family of unknown function DNA_pol_phi PF04931.13 KKK24505.1 - 4.1 5.4 10.4 2.2 6.3 4.7 2.3 2 1 0 2 2 2 0 DNA polymerase phi ECR1_N PF14382.6 KKK24506.1 - 1.3e-14 53.7 0.1 3e-14 52.5 0.1 1.7 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region KH_6 PF15985.5 KKK24506.1 - 6.1e-06 26.5 0.9 1.2e-05 25.6 0.9 1.5 1 0 0 1 1 1 1 KH domain EXOSC1 PF10447.9 KKK24506.1 - 0.082 13.5 0.4 1.6 9.3 0.1 2.6 2 0 0 2 2 2 0 Exosome component EXOSC1/CSL4 SH2_2 PF14633.6 KKK24507.1 - 1.6e-85 285.9 0.0 4.4e-85 284.5 0.0 1.8 1 0 0 1 1 1 1 SH2 domain HTH_44 PF14641.6 KKK24507.1 - 2.5e-35 121.4 7.8 3.8e-35 120.8 2.0 2.7 2 0 0 2 2 2 1 Helix-turn-helix DNA-binding domain of SPT6 YqgF PF14639.6 KKK24507.1 - 8.7e-31 106.7 0.1 3.9e-30 104.6 0.0 2.2 2 0 0 2 2 2 1 Holliday-junction resolvase-like of SPT6 HHH_7 PF14635.6 KKK24507.1 - 8.9e-31 106.3 0.0 1.7e-30 105.4 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif SPT6_acidic PF14632.6 KKK24507.1 - 2.8e-17 63.1 27.5 2.8e-17 63.1 27.5 4.9 4 2 1 5 5 5 1 Acidic N-terminal SPT6 HHH_9 PF17674.1 KKK24507.1 - 5.6e-08 33.6 2.3 2.4e-06 28.4 2.6 3.6 2 1 0 2 2 2 1 HHH domain SH2 PF00017.24 KKK24507.1 - 3.2e-05 23.9 0.0 8.4e-05 22.6 0.0 1.8 1 0 0 1 1 1 1 SH2 domain HHH_3 PF12836.7 KKK24507.1 - 0.0047 17.2 0.0 0.011 15.9 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif Tex_N PF09371.10 KKK24507.1 - 0.0073 16.0 7.5 0.076 12.7 0.0 3.9 4 0 0 4 4 4 1 Tex-like protein N-terminal domain Oxysterol_BP PF01237.18 KKK24508.1 - 2.2e-114 382.2 0.0 5.3e-114 380.9 0.0 1.6 1 0 0 1 1 1 1 Oxysterol-binding protein PH_8 PF15409.6 KKK24508.1 - 1.3e-37 128.0 0.5 2.3e-37 127.1 0.0 1.7 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.29 KKK24508.1 - 3.7e-08 33.8 0.0 1.1e-07 32.4 0.0 1.8 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 KKK24508.1 - 0.0092 16.4 0.7 5 7.6 0.1 2.6 1 1 0 2 2 2 2 Pleckstrin homology domain NAD_binding_10 PF13460.6 KKK24509.1 - 0.0027 17.6 0.0 0.0043 17.0 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 KKK24509.1 - 0.0077 15.4 0.0 0.011 14.9 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 KKK24509.1 - 0.049 13.1 0.0 0.065 12.7 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 KKK24509.1 - 0.068 13.6 0.0 0.11 13.0 0.0 1.3 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Mac PF12464.8 KKK24510.1 - 2.2e-14 53.4 0.2 5.7e-14 52.1 0.2 1.8 1 0 0 1 1 1 1 Maltose acetyltransferase Hexapep PF00132.24 KKK24510.1 - 3.7e-11 42.3 12.4 7.1e-11 41.4 4.4 3.3 3 0 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KKK24510.1 - 2.3e-09 36.8 4.6 2.3e-09 36.8 4.6 2.8 3 0 0 3 3 3 1 Hexapeptide repeat of succinyl-transferase Zn_clus PF00172.18 KKK24510.1 - 1.6e-07 31.3 7.5 1.6e-07 31.3 7.5 2.1 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_transf_54 PF04666.13 KKK24512.1 - 9.5e-12 44.4 0.0 4.3e-09 35.6 0.1 3.0 2 1 0 2 2 2 2 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region Abhydrolase_6 PF12697.7 KKK24513.1 - 2.6e-09 38.0 1.5 2.6e-09 38.0 1.5 2.0 1 1 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KKK24513.1 - 8.2e-07 28.5 0.0 9.1e-06 25.1 0.0 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KKK24513.1 - 0.00021 21.1 0.1 0.015 15.0 0.0 2.2 1 1 1 2 2 2 1 alpha/beta hydrolase fold Lipase_3 PF01764.25 KKK24513.1 - 0.0022 17.9 0.0 0.0036 17.2 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) DUF676 PF05057.14 KKK24513.1 - 0.0041 16.7 0.0 0.0062 16.1 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_2 PF02230.16 KKK24513.1 - 0.0091 15.8 0.0 4.6 7.0 0.0 2.1 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase DUF1749 PF08538.10 KKK24513.1 - 0.028 13.5 0.0 0.067 12.3 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1749) LIDHydrolase PF10230.9 KKK24513.1 - 0.12 11.9 0.0 0.31 10.6 0.0 1.7 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase Epimerase PF01370.21 KKK24514.1 - 0.0069 15.9 0.1 0.12 11.8 0.0 2.4 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 KKK24514.1 - 0.0083 15.3 0.0 0.15 11.2 0.0 2.2 2 0 0 2 2 2 1 Male sterility protein Semialdhyde_dh PF01118.24 KKK24514.1 - 0.024 15.1 0.0 0.041 14.3 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.15 KKK24514.1 - 0.034 13.3 0.1 0.16 11.0 0.0 1.9 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein DapB_N PF01113.20 KKK24514.1 - 0.12 12.6 0.0 0.25 11.5 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus p450 PF00067.22 KKK24515.1 - 5.5e-52 177.1 0.0 7.2e-52 176.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 GtrA PF04138.14 KKK24515.1 - 0.38 11.0 5.7 0.9 9.8 5.7 1.6 1 0 0 1 1 1 0 GtrA-like protein FSH1 PF03959.13 KKK24516.1 - 3.3e-24 85.8 0.0 3.8e-24 85.5 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 KKK24516.1 - 0.0055 16.5 0.1 0.011 15.5 0.1 1.5 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase MazG PF03819.17 KKK24516.1 - 0.058 13.6 0.3 0.65 10.2 0.0 2.2 2 0 0 2 2 2 0 MazG nucleotide pyrophosphohydrolase domain Pkinase PF00069.25 KKK24517.1 - 1.4e-64 218.0 0.0 1.8e-64 217.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK24517.1 - 2.2e-36 125.5 0.0 3e-36 125.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KKK24517.1 - 1.2e-05 24.3 0.0 1.8e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KKK24517.1 - 0.00059 19.2 0.0 0.001 18.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 KKK24517.1 - 0.014 14.5 0.0 0.02 13.9 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Haspin_kinase PF12330.8 KKK24517.1 - 0.014 14.3 0.0 0.025 13.6 0.0 1.5 1 1 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 KKK24517.1 - 0.036 14.0 0.0 0.075 12.9 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 KKK24517.1 - 0.073 12.7 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 RIO1 family LysM PF01476.20 KKK24518.1 - 1e-22 79.9 0.1 0.00022 21.2 0.0 5.3 5 0 0 5 5 5 5 LysM domain HAP2-GCS1 PF10699.9 KKK24518.1 - 0.0036 17.2 0.5 0.49 10.4 0.0 3.4 2 1 0 2 2 2 2 Male gamete fusion factor Svf1 PF08622.10 KKK24546.1 - 8e-07 29.2 0.8 1e-06 28.9 0.8 1.1 1 0 0 1 1 1 1 Svf1-like N-terminal lipocalin domain LisH_2 PF16045.5 KKK24546.1 - 0.083 11.9 0.2 0.14 11.2 0.2 1.4 1 0 0 1 1 1 0 LisH Ribosomal_L11 PF00298.19 KKK24547.1 - 2.6e-28 98.3 0.1 4.7e-28 97.5 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Ribosomal_L11_N PF03946.14 KKK24547.1 - 1e-26 92.5 0.3 1.6e-26 91.9 0.3 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain DUF3613 PF12266.8 KKK24547.1 - 0.14 12.0 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3613) Pkinase PF00069.25 KKK24548.1 - 9e-44 149.8 0.0 3.5e-42 144.6 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Mito_carr PF00153.27 KKK24548.1 - 9.5e-37 124.8 1.0 3e-15 55.9 0.1 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein Pkinase_Tyr PF07714.17 KKK24548.1 - 2.4e-19 69.6 0.0 4.1e-19 68.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KKK24548.1 - 0.025 14.5 0.0 0.068 13.1 0.0 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KKK24548.1 - 0.044 12.7 0.0 0.081 11.9 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain DUF3337 PF11816.8 KKK24549.1 - 1.1e-54 184.9 0.0 2.7e-54 183.6 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3337) ATP_bind_3 PF01171.20 KKK24549.1 - 1.9e-42 145.1 0.0 4.2e-42 143.9 0.0 1.6 1 1 0 1 1 1 1 PP-loop family WD40 PF00400.32 KKK24549.1 - 6.6e-17 61.6 17.0 6.1e-05 23.7 0.1 7.2 6 0 0 6 6 6 4 WD domain, G-beta repeat Nup160 PF11715.8 KKK24549.1 - 0.0045 15.7 0.3 0.08 11.6 0.1 2.7 3 0 0 3 3 3 1 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 KKK24549.1 - 0.0049 17.1 0.2 0.11 12.8 0.1 3.0 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain ATP-synt_C PF00137.21 KKK24581.1 - 3.1e-09 37.1 13.4 5e-09 36.4 13.4 1.4 1 0 0 1 1 1 1 ATP synthase subunit C DUF4139 PF13598.6 KKK24582.1 - 9.2e-32 110.4 0.0 2e-31 109.4 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4139) DUF4140 PF13600.6 KKK24582.1 - 3.7e-21 75.4 0.5 3.7e-21 75.4 0.5 3.8 3 1 0 3 3 3 1 N-terminal domain of unknown function (DUF4140) Nucleoporin_FG PF13634.6 KKK24582.1 - 0.038 14.8 15.8 0.25 12.2 15.6 2.2 1 1 0 1 1 1 0 Nucleoporin FG repeat region PRIMA1 PF16101.5 KKK24582.1 - 0.55 10.3 3.5 1.5 8.9 3.5 1.7 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 DUF4407 PF14362.6 KKK24582.1 - 0.77 9.0 12.1 1.8 7.8 12.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) zf-CSL PF05207.13 KKK24583.1 - 1.1e-19 69.8 1.3 1.9e-19 69.1 1.3 1.4 1 0 0 1 1 1 1 CSL zinc finger DnaJ PF00226.31 KKK24583.1 - 1.3e-12 47.6 0.8 1e-10 41.6 0.8 2.2 1 1 0 1 1 1 1 DnaJ domain peroxidase PF00141.23 KKK24584.1 - 3e-49 167.8 0.0 4.9e-49 167.1 0.0 1.3 1 0 0 1 1 1 1 Peroxidase ArfGap PF01412.18 KKK24585.1 - 1.3e-36 125.2 0.3 2.1e-36 124.5 0.3 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf UBA PF00627.31 KKK24585.1 - 0.049 13.5 0.0 0.11 12.4 0.0 1.7 1 0 0 1 1 1 0 UBA/TS-N domain BTB PF00651.31 KKK24586.1 - 2e-13 50.5 0.2 3.9e-12 46.4 0.0 2.1 2 0 0 2 2 2 1 BTB/POZ domain JmjC PF02373.22 KKK24596.1 - 4.4e-37 127.0 0.8 4.4e-37 127.0 0.8 2.7 4 0 0 4 4 4 1 JmjC domain, hydroxylase zf-HC5HC2H PF13771.6 KKK24596.1 - 3e-18 65.8 4.4 7e-18 64.7 4.4 1.7 1 0 0 1 1 1 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 KKK24596.1 - 9.7e-18 64.3 4.9 1.9e-17 63.4 4.9 1.4 1 0 0 1 1 1 1 PHD-zinc-finger like domain JmjN PF02375.17 KKK24596.1 - 4.1e-15 55.5 0.2 1.1e-14 54.1 0.2 1.8 1 0 0 1 1 1 1 jmjN domain EPL1 PF10513.9 KKK24596.1 - 0.53 10.7 12.0 0.53 10.7 7.7 2.5 2 0 0 2 2 2 0 Enhancer of polycomb-like Folliculin PF11704.8 KKK24596.1 - 3.1 7.6 8.0 0.53 10.1 3.3 2.0 2 0 0 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport ACBP PF00887.19 KKK24597.1 - 2.3e-21 75.8 0.0 4.3e-21 74.9 0.0 1.5 1 0 0 1 1 1 1 Acyl CoA binding protein TraP PF07296.11 KKK24597.1 - 0.17 11.0 2.0 0.32 10.2 2.0 1.3 1 0 0 1 1 1 0 TraP protein SDA1 PF05285.12 KKK24597.1 - 0.3 10.5 14.4 0.42 10.0 14.4 1.2 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 KKK24597.1 - 0.44 8.8 14.1 0.63 8.3 14.1 1.2 1 0 0 1 1 1 0 CDC45-like protein Lin-8 PF03353.15 KKK24597.1 - 1 8.9 10.7 0.88 9.1 7.7 2.0 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist Nop14 PF04147.12 KKK24597.1 - 2 6.6 16.9 3.6 5.7 16.9 1.4 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 KKK24597.1 - 8.3 5.6 14.8 13 4.9 14.8 1.3 1 0 0 1 1 1 0 BUD22 CHCH PF06747.13 KKK24598.1 - 6.7e-06 26.1 4.6 6.7e-06 26.1 4.6 2.5 3 0 0 3 3 3 2 CHCH domain CX9C PF16860.5 KKK24598.1 - 0.0032 17.5 9.5 0.0039 17.2 3.3 2.3 2 0 0 2 2 2 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, DNA_circ_N PF07157.12 KKK24598.1 - 0.18 12.2 0.0 0.26 11.7 0.0 1.3 1 0 0 1 1 1 0 DNA circularisation protein N-terminus Pet191_N PF10203.9 KKK24598.1 - 0.26 11.6 10.3 1.4 9.2 1.2 2.9 1 1 1 3 3 3 0 Cytochrome c oxidase assembly protein PET191 Cmc1 PF08583.10 KKK24598.1 - 0.63 10.1 14.9 1.4 9.0 4.0 2.3 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like COX6B PF02297.17 KKK24598.1 - 1.3 9.3 10.0 7.2 6.9 0.7 2.2 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb GTP_EFTU_D2 PF03144.25 KKK24609.1 - 3.1e-14 53.1 1.0 4.1e-14 52.7 1.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.6 KKK24609.1 - 0.0012 18.7 0.9 0.0017 18.2 0.9 1.2 1 0 0 1 1 1 1 Elongation factor Tu domain 4 GTP_EFTU_D3 PF03143.17 KKK24609.1 - 0.0023 18.2 0.0 0.012 15.9 0.0 2.0 2 1 0 2 2 2 1 Elongation factor Tu C-terminal domain gpW PF02831.15 KKK24609.1 - 0.13 12.1 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 gpW tRNA-synt_1g PF09334.11 KKK24619.1 - 3.4e-151 503.4 0.0 4.3e-151 503.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 KKK24619.1 - 1.6e-09 36.6 0.1 2.8e-06 25.9 0.0 3.2 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) OppC_N PF12911.7 KKK24619.1 - 0.031 14.3 0.4 0.075 13.0 0.4 1.6 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C Anticodon_1 PF08264.13 KKK24619.1 - 0.033 14.1 0.0 0.073 13.0 0.0 1.5 1 0 0 1 1 1 0 Anticodon-binding domain of tRNA DUF1682 PF07946.14 KKK24619.1 - 5.3 6.2 6.9 9.4 5.3 6.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) WD40 PF00400.32 KKK24620.1 - 1.9e-17 63.3 1.4 0.007 17.2 0.0 5.4 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKK24620.1 - 1.8e-06 28.2 0.0 0.0044 17.3 0.0 4.4 2 2 4 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KKK24620.1 - 0.0016 17.5 0.1 0.079 11.9 0.0 2.9 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KKK24620.1 - 0.033 13.5 0.0 0.059 12.7 0.0 1.4 1 0 0 1 1 1 0 WD40-like domain PXA PF02194.15 KKK24622.1 - 1.7e-49 168.3 0.4 8.4e-49 166.0 0.4 2.3 2 0 0 2 2 2 1 PXA domain Nexin_C PF08628.12 KKK24622.1 - 5.3e-25 88.2 0.0 1.8e-24 86.5 0.0 2.0 1 0 0 1 1 1 1 Sorting nexin C terminal PX PF00787.24 KKK24622.1 - 1.5e-21 76.5 0.5 3.6e-21 75.3 0.5 1.7 1 0 0 1 1 1 1 PX domain RGS PF00615.19 KKK24622.1 - 1.2e-11 44.9 0.1 2.8e-11 43.7 0.1 1.7 1 0 0 1 1 1 1 Regulator of G protein signaling domain RRP36 PF06102.12 KKK24622.1 - 0.0031 17.5 1.7 0.66 9.9 0.1 2.7 2 0 0 2 2 2 2 rRNA biogenesis protein RRP36 Mucin PF01456.17 KKK24622.1 - 3.3 7.7 20.7 8.1 6.4 20.7 1.6 1 0 0 1 1 1 0 Mucin-like glycoprotein PEMT PF04191.13 KKK24623.1 - 3.7e-33 114.1 2.6 9e-33 112.9 1.3 2.0 2 0 0 2 2 2 1 Phospholipid methyltransferase YrhK PF14145.6 KKK24623.1 - 0.022 14.6 0.6 0.11 12.4 0.1 2.3 2 0 0 2 2 2 0 YrhK-like protein Yae1_N PF09811.9 KKK24624.1 - 2e-09 37.0 3.4 3.1e-09 36.4 3.4 1.3 1 0 0 1 1 1 1 Essential protein Yae1, N terminal ICE2 PF08426.10 KKK24625.1 - 9.6e-155 515.7 13.4 1.1e-154 515.5 13.4 1.0 1 0 0 1 1 1 1 ICE2 ADH_zinc_N PF00107.26 KKK24628.1 - 2e-27 95.8 1.4 3.1e-27 95.1 1.4 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KKK24628.1 - 1.9e-10 41.9 0.1 3.3e-10 41.1 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KKK24628.1 - 4.8e-06 26.4 0.0 3.7e-05 23.6 0.0 2.4 3 0 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 KKK24628.1 - 0.011 15.0 0.7 0.02 14.2 0.7 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain adh_short PF00106.25 KKK24628.1 - 0.083 12.3 0.3 0.11 11.9 0.3 1.2 1 0 0 1 1 1 0 short chain dehydrogenase Clr5 PF14420.6 KKK24629.1 - 1.9e-12 47.2 0.9 3.4e-12 46.4 0.9 1.4 1 0 0 1 1 1 1 Clr5 domain SPX PF03105.19 KKK24629.1 - 0.0075 16.2 5.0 0.0095 15.9 5.0 1.2 1 0 0 1 1 1 1 SPX domain SNF2_N PF00176.23 KKK24630.1 - 1.7e-65 221.1 0.6 2.8e-65 220.3 0.6 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KKK24630.1 - 2.7e-19 69.5 0.0 8.5e-19 67.9 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KKK24630.1 - 5.7e-10 39.5 0.0 1.3e-09 38.3 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HSA PF07529.13 KKK24630.1 - 6.2e-09 36.1 9.8 6.2e-09 36.1 9.8 2.6 2 0 0 2 2 2 1 HSA DEAD PF00270.29 KKK24630.1 - 0.00012 21.9 0.0 0.0004 20.2 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase DEAD_2 PF06733.15 KKK24630.1 - 0.14 11.7 0.0 0.32 10.6 0.0 1.5 1 0 0 1 1 1 0 DEAD_2 DUF3417 PF11897.8 KKK24630.1 - 0.85 10.1 3.2 3 8.3 3.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3417) NDUF_B8 PF05821.11 KKK24631.1 - 4.7e-09 36.3 1.2 6.8e-09 35.8 1.2 1.3 1 1 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) Membr_traf_MHD PF10540.9 KKK24632.1 - 1.4e-21 77.2 1.4 2.5e-11 44.0 0.6 3.2 2 1 1 3 3 3 2 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.30 KKK24632.1 - 2.5e-15 56.6 0.0 5.5e-15 55.5 0.0 1.6 1 0 0 1 1 1 1 C2 domain DUF810 PF05664.11 KKK24632.1 - 4.1e-09 35.5 3.2 1.8e-07 30.1 0.9 2.7 3 0 0 3 3 3 2 Plant family of unknown function (DUF810) Zds_C PF08632.10 KKK24647.1 - 4.5e-28 96.8 1.2 8e-28 96.0 1.2 1.4 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term OPT PF03169.15 KKK24648.1 - 3.3e-147 491.8 51.9 3.8e-147 491.6 51.9 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Arrestin_C PF02752.22 KKK24649.1 - 5.4e-19 69.0 0.0 9.7e-19 68.2 0.0 1.4 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 KKK24649.1 - 1.9e-11 44.2 0.0 3.2e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 KKK24649.1 - 0.0017 18.1 0.0 0.0042 16.8 0.0 1.6 2 0 0 2 2 2 1 Arrestin_N terminal like EF_assoc_2 PF08356.12 KKK24650.1 - 6e-34 115.9 0.0 1.2e-33 115.0 0.0 1.5 1 0 0 1 1 1 1 EF hand associated EF_assoc_1 PF08355.12 KKK24650.1 - 4.9e-31 106.2 0.2 8.3e-31 105.4 0.2 1.4 1 0 0 1 1 1 1 EF hand associated Ras PF00071.22 KKK24650.1 - 1e-25 90.3 0.0 5.8e-14 52.0 0.0 2.2 2 0 0 2 2 2 2 Ras family Roc PF08477.13 KKK24650.1 - 5.3e-13 49.2 0.0 1.5e-07 31.7 0.0 2.4 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 KKK24650.1 - 8.3e-11 42.0 0.0 0.00023 21.2 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase EF-hand_1 PF00036.32 KKK24650.1 - 8.6e-06 24.9 1.2 0.026 14.0 0.1 2.6 2 0 0 2 2 2 2 EF hand AAA_16 PF13191.6 KKK24650.1 - 8e-05 23.1 0.1 0.34 11.3 0.0 2.9 3 0 0 3 3 3 2 AAA ATPase domain RsgA_GTPase PF03193.16 KKK24650.1 - 0.00014 21.8 0.4 2 8.3 0.0 3.5 3 0 0 3 3 3 1 RsgA GTPase EF-hand_7 PF13499.6 KKK24650.1 - 0.00016 22.0 0.0 0.035 14.5 0.0 2.6 2 0 0 2 2 2 1 EF-hand domain pair AAA_22 PF13401.6 KKK24650.1 - 0.00029 21.1 0.7 1.5 9.1 0.0 3.1 2 1 1 3 3 3 2 AAA domain EF-hand_8 PF13833.6 KKK24650.1 - 0.0003 20.6 0.3 0.19 11.6 0.0 2.7 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 KKK24650.1 - 0.00051 19.8 0.9 0.18 11.8 0.1 2.6 2 0 0 2 2 2 1 EF-hand domain AAA_28 PF13521.6 KKK24650.1 - 0.00068 19.9 0.1 0.45 10.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain Dynamin_N PF00350.23 KKK24650.1 - 0.0009 19.3 2.6 0.87 9.6 0.2 2.9 3 1 0 3 3 2 2 Dynamin family AAA_29 PF13555.6 KKK24650.1 - 0.002 17.8 0.3 1.4 8.7 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain RNA_helicase PF00910.22 KKK24650.1 - 0.0038 17.6 0.0 1.2 9.6 0.0 2.7 2 0 0 2 2 2 1 RNA helicase ABC_tran PF00005.27 KKK24650.1 - 0.0041 17.6 0.0 2.9 8.4 0.0 2.5 2 0 0 2 2 2 1 ABC transporter Viral_helicase1 PF01443.18 KKK24650.1 - 0.0048 16.7 0.3 0.11 12.2 0.0 2.7 2 1 0 2 2 2 1 Viral (Superfamily 1) RNA helicase NACHT PF05729.12 KKK24650.1 - 0.015 15.2 0.1 7.5 6.4 0.0 2.7 2 0 0 2 2 2 0 NACHT domain Ploopntkinase3 PF18751.1 KKK24650.1 - 0.018 15.0 0.0 1.7 8.5 0.0 2.3 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 AAA_7 PF12775.7 KKK24650.1 - 0.02 14.4 0.2 1.7 8.1 0.0 2.4 2 1 0 2 2 2 0 P-loop containing dynein motor region FtsK_SpoIIIE PF01580.18 KKK24650.1 - 0.021 14.2 0.4 1.4 8.2 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family GTP_EFTU PF00009.27 KKK24650.1 - 0.021 14.4 0.2 3 7.3 0.0 2.7 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain AAA_18 PF13238.6 KKK24650.1 - 0.023 15.2 0.4 1.7 9.2 0.3 2.7 2 1 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KKK24650.1 - 0.026 14.3 0.2 0.44 10.3 0.1 2.2 2 0 0 2 2 2 0 AAA domain Septin PF00735.18 KKK24650.1 - 0.027 13.8 0.2 0.79 8.9 0.0 2.4 3 0 0 3 3 2 0 Septin AAA_25 PF13481.6 KKK24650.1 - 0.038 13.6 0.1 10 5.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain EF-hand_5 PF13202.6 KKK24650.1 - 0.045 13.3 2.8 0.83 9.3 0.2 2.6 2 0 0 2 2 2 0 EF hand EF-hand_10 PF14788.6 KKK24650.1 - 0.05 13.5 0.5 1.2 9.0 0.1 2.7 2 0 0 2 2 2 0 EF hand DUF815 PF05673.13 KKK24650.1 - 0.063 12.4 0.2 2.5 7.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Pox_H7 PF04787.12 KKK24650.1 - 0.069 13.7 0.0 2.6 8.6 0.0 2.3 2 0 0 2 2 2 0 Late protein H7 DUF3201 PF11447.8 KKK24650.1 - 0.082 12.4 0.1 0.28 10.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3201) AAA PF00004.29 KKK24650.1 - 0.1 13.0 0.8 14 6.1 0.0 3.4 4 1 0 4 4 3 0 ATPase family associated with various cellular activities (AAA) ATP_bind_1 PF03029.17 KKK24650.1 - 0.11 12.2 2.4 14 5.4 0.0 3.5 4 0 0 4 4 4 0 Conserved hypothetical ATP binding protein AAA_33 PF13671.6 KKK24650.1 - 0.11 12.6 0.0 20 5.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 KKK24650.1 - 0.12 12.3 0.6 31 4.5 0.0 3.2 2 1 1 3 3 3 0 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.12 KKK24650.1 - 0.18 11.1 0.0 2.1 7.5 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin IIGP PF05049.13 KKK24650.1 - 0.18 10.8 0.8 1.6 7.7 0.1 2.2 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) cobW PF02492.19 KKK24650.1 - 0.25 10.9 3.7 2.4 7.7 0.3 3.7 4 1 0 4 4 4 0 CobW/HypB/UreG, nucleotide-binding domain MCM PF00493.23 KKK24650.1 - 0.25 10.4 0.0 3.8 6.5 0.0 2.3 2 0 0 2 2 2 0 MCM P-loop domain ANAPC4_WD40 PF12894.7 KKK24651.1 - 3.7e-10 40.0 0.0 0.0099 16.2 0.0 3.4 2 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KKK24651.1 - 7.5e-09 36.1 11.1 0.0012 19.6 0.2 5.7 5 1 0 5 5 5 3 WD domain, G-beta repeat IKI3 PF04762.12 KKK24651.1 - 0.00052 18.2 0.0 0.0022 16.1 0.0 1.7 1 1 1 2 2 2 1 IKI3 family eIF2A PF08662.11 KKK24651.1 - 0.0024 17.8 0.1 0.035 14.0 0.0 2.2 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 KKK24651.1 - 0.039 12.5 0.0 0.12 10.9 0.0 1.7 2 0 0 2 2 2 0 Cytochrome D1 heme domain DUF5005 PF16396.5 KKK24651.1 - 0.17 10.6 0.0 0.26 9.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5005) Ysc84 PF04366.12 KKK24652.1 - 7.9e-41 138.8 0.3 1.4e-40 138.0 0.3 1.4 1 0 0 1 1 1 1 Las17-binding protein actin regulator SH3_1 PF00018.28 KKK24652.1 - 2.1e-13 49.6 0.3 6.6e-13 48.0 0.2 1.9 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 KKK24652.1 - 3.6e-11 42.7 0.0 1.1e-10 41.2 0.1 1.8 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 KKK24652.1 - 6.8e-11 41.7 0.5 1.7e-10 40.4 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain DUF3104 PF11302.8 KKK24652.1 - 0.16 11.7 0.1 0.35 10.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3104) EMP24_GP25L PF01105.24 KKK24653.1 - 7.9e-42 143.2 0.0 9.6e-42 143.0 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD EzrA PF06160.12 KKK24653.1 - 0.031 12.4 0.4 0.04 12.1 0.4 1.0 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA APH PF01636.23 KKK24654.1 - 8.6e-23 81.5 0.0 1.2e-22 81.1 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KKK24654.1 - 3.1e-06 26.9 0.0 5.2e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 KKK24654.1 - 0.011 15.3 0.0 0.074 12.7 0.0 2.0 2 0 0 2 2 2 0 RIO1 family EcKinase PF02958.20 KKK24654.1 - 0.19 11.0 0.0 0.29 10.4 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase DUF3130 PF11328.8 KKK24655.1 - 0.047 13.9 0.0 0.2 11.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3130 RTA1 PF04479.13 KKK24668.1 - 3.7e-71 239.0 11.7 3.7e-71 239.0 11.7 1.3 2 0 0 2 2 2 1 RTA1 like protein Ninjurin PF04923.12 KKK24668.1 - 3.2 7.7 6.2 18 5.3 0.5 3.0 3 1 0 3 3 3 0 Ninjurin XFP_C PF09363.10 KKK24669.1 - 1.5e-09 37.6 0.3 1.6e-09 37.5 0.3 1.0 1 0 0 1 1 1 1 XFP C-terminal domain XFP_N PF09364.10 KKK24670.1 - 1.9e-143 477.7 0.0 8.4e-142 472.3 0.0 2.1 1 1 0 1 1 1 1 XFP N-terminal domain XFP PF03894.15 KKK24670.1 - 8.7e-76 253.5 0.0 1.2e-75 253.0 0.0 1.2 1 0 0 1 1 1 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase XFP_C PF09363.10 KKK24670.1 - 1.9e-29 102.6 0.0 4e-29 101.5 0.0 1.5 1 0 0 1 1 1 1 XFP C-terminal domain TPP_enzyme_C PF02775.21 KKK24670.1 - 0.0049 16.7 0.1 0.01 15.6 0.1 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain SH3_2 PF07653.17 KKK24670.1 - 0.13 11.9 0.1 0.36 10.5 0.1 1.7 1 0 0 1 1 1 0 Variant SH3 domain AAA_16 PF13191.6 KKK24671.1 - 6e-08 33.3 0.0 1.4e-07 32.0 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain ATPase_2 PF01637.18 KKK24671.1 - 0.0014 18.6 0.0 0.0024 17.8 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_25 PF13481.6 KKK24671.1 - 0.011 15.3 0.0 0.076 12.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KKK24671.1 - 0.041 13.4 0.0 0.076 12.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_5 PF07728.14 KKK24671.1 - 0.041 13.9 0.1 0.21 11.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Acetate_kinase PF00871.17 KKK24672.1 - 4.6e-87 292.3 0.0 5.5e-87 292.0 0.0 1.1 1 0 0 1 1 1 1 Acetokinase family AATase PF07247.12 KKK24681.1 - 1.7e-08 33.5 0.0 3e-08 32.7 0.0 1.4 1 1 0 1 1 1 1 Alcohol acetyltransferase WES_acyltransf PF03007.16 KKK24681.1 - 0.083 12.6 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Wax ester synthase-like Acyl-CoA acyltransferase domain Fungal_trans_2 PF11951.8 KKK24682.1 - 4.3e-06 25.8 0.0 6.2e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain MmgE_PrpD PF03972.14 KKK24683.1 - 4.4e-101 338.6 5.1 1.9e-50 171.7 2.5 2.8 1 1 1 2 2 2 2 MmgE/PrpD family DUF5570 PF17731.1 KKK24683.1 - 0.1 12.7 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5570) Citrate_synt PF00285.21 KKK24684.1 - 1.5e-91 307.2 0.0 1.8e-91 306.9 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain DIT1_PvcA PF05141.12 KKK24685.1 - 1.1e-93 313.7 0.0 1.7e-93 313.1 0.0 1.3 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein AMP-binding PF00501.28 KKK24685.1 - 3.9e-25 88.3 0.0 6.6e-25 87.6 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Transferase PF02458.15 KKK24685.1 - 2.9e-07 29.5 0.0 0.00086 18.1 0.0 2.8 3 0 0 3 3 3 2 Transferase family PP-binding PF00550.25 KKK24685.1 - 5.4e-07 29.9 0.0 1.1e-06 28.8 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Abhydrolase_3 PF07859.13 KKK24686.1 - 3.4e-44 151.2 0.0 5.5e-44 150.6 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KKK24686.1 - 5.7e-09 35.4 0.3 1.5e-08 34.0 0.3 1.5 1 1 0 1 1 1 1 Carboxylesterase family AATase PF07247.12 KKK24687.1 - 1.4e-11 43.7 0.0 1.8e-06 26.8 0.0 2.2 1 1 1 2 2 2 2 Alcohol acetyltransferase F-box-like PF12937.7 KKK24688.1 - 4.6e-08 32.8 3.3 1.4e-05 24.9 0.1 3.0 3 0 0 3 3 3 2 F-box-like F-box PF00646.33 KKK24688.1 - 3.5e-05 23.6 2.1 0.00019 21.2 0.3 2.6 2 0 0 2 2 2 1 F-box domain Metallophos PF00149.28 KKK24689.1 - 1.9e-19 71.0 0.3 3.8e-19 70.0 0.3 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.6 KKK24689.1 - 2.2e-14 54.1 0.2 6.2e-14 52.6 0.2 1.9 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C Pur_ac_phosph_N PF16656.5 KKK24689.1 - 1e-13 51.7 0.1 2.5e-13 50.4 0.1 1.7 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain fn3 PF00041.21 KKK24689.1 - 0.00049 20.4 0.1 0.0017 18.7 0.1 1.8 1 1 0 1 1 1 1 Fibronectin type III domain Ank_2 PF12796.7 KKK24690.1 - 1.4e-61 205.1 0.9 7.5e-18 64.9 0.0 5.2 1 1 2 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KKK24690.1 - 2.8e-54 180.8 0.0 1.6e-09 38.1 0.0 6.8 2 2 5 7 7 7 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 KKK24690.1 - 4.9e-48 160.6 0.0 2.1e-10 40.7 0.0 6.4 2 1 6 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 KKK24690.1 - 3.9e-47 152.8 0.0 0.0008 19.7 0.0 9.5 10 0 0 10 10 10 9 Ankyrin repeat Ank PF00023.30 KKK24690.1 - 2.5e-43 144.7 1.9 1.6e-05 25.1 0.0 9.2 10 0 0 10 10 10 7 Ankyrin repeat VWA_3_C PF18571.1 KKK24690.1 - 7.9e-07 28.9 16.4 0.0049 16.7 0.0 7.1 8 0 0 8 8 8 2 von Willebrand factor type A C-terminal domain F-box-like PF12937.7 KKK24690.1 - 2.6e-05 24.0 0.6 4.7e-05 23.2 0.6 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KKK24690.1 - 0.009 15.9 0.5 0.015 15.1 0.5 1.3 1 0 0 1 1 1 1 F-box domain Nse4-Nse3_bdg PF15412.6 KKK24690.1 - 0.23 11.6 2.7 33 4.7 0.0 4.4 6 0 0 6 6 6 0 Binding domain of Nse4/EID3 to Nse3-MAGE Glyoxalase_6 PF18029.1 KKK24691.1 - 0.00016 22.4 0.0 0.00024 21.9 0.0 1.3 1 1 0 1 1 1 1 Glyoxalase-like domain Hydrolase_4 PF12146.8 KKK24692.1 - 5.4e-38 130.6 0.0 1.1e-37 129.6 0.0 1.5 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KKK24692.1 - 8.5e-08 33.1 0.8 3.3e-07 31.1 0.3 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_C14 PF00656.22 KKK24692.1 - 0.0015 18.5 0.0 0.003 17.6 0.0 1.4 1 0 0 1 1 1 1 Caspase domain Abhydrolase_1 PF00561.20 KKK24692.1 - 0.011 15.4 0.5 0.78 9.3 0.5 2.3 1 1 0 1 1 1 0 alpha/beta hydrolase fold DUF1749 PF08538.10 KKK24692.1 - 0.015 14.4 0.0 0.024 13.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) Pirin PF02678.16 KKK24693.1 - 1.6e-23 82.7 0.6 4.3e-23 81.4 0.6 1.7 1 1 0 1 1 1 1 Pirin Cupin_2 PF07883.11 KKK24693.1 - 3.6e-06 26.6 1.3 0.00015 21.4 0.3 2.9 2 1 0 2 2 2 1 Cupin domain Pirin_C_2 PF17954.1 KKK24693.1 - 0.11 12.6 0.1 0.39 10.9 0.1 1.9 1 1 0 1 1 1 0 Quercetinase C-terminal cupin domain MFS_1 PF07690.16 KKK24694.1 - 2.3e-14 53.1 53.6 8.6e-13 47.9 51.9 2.6 1 1 0 1 1 1 1 Major Facilitator Superfamily MmgE_PrpD PF03972.14 KKK24695.1 - 1.8e-61 208.0 0.2 6.1e-60 203.0 0.2 2.0 1 1 0 1 1 1 1 MmgE/PrpD family Sua5_yciO_yrdC PF01300.18 KKK24696.1 - 5e-14 52.2 0.0 7.2e-14 51.7 0.0 1.2 1 0 0 1 1 1 1 Telomere recombination RPA43_OB PF17875.1 KKK24696.1 - 0.15 12.7 0.3 1.9 9.1 0.8 2.0 2 0 0 2 2 2 0 RPA43 OB domain in RNA Pol I Polysacc_deac_1 PF01522.21 KKK24714.1 - 1e-27 96.5 0.0 2.6e-27 95.2 0.0 1.7 1 1 0 1 1 1 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.19 KKK24714.1 - 1.5e-08 35.0 44.0 2.2e-05 24.8 15.4 2.9 2 1 0 2 2 2 2 Chitin recognition protein HEAT_2 PF13646.6 KKK24715.1 - 0.00036 20.9 0.0 0.0037 17.6 0.0 2.8 3 2 1 4 4 4 1 HEAT repeats RTP1_C1 PF10363.9 KKK24715.1 - 0.00052 20.2 0.0 0.0011 19.1 0.0 1.5 1 0 0 1 1 1 1 Required for nuclear transport of RNA pol II C-terminus 1 HEAT PF02985.22 KKK24715.1 - 0.001 19.1 1.4 2.2 8.8 0.0 4.2 4 0 0 4 4 4 1 HEAT repeat MMS19_C PF12460.8 KKK24715.1 - 0.0011 18.1 0.2 0.2 10.8 0.0 2.6 1 1 1 3 3 3 2 RNAPII transcription regulator C-terminal Adaptin_N PF01602.20 KKK24715.1 - 0.02 13.5 0.1 13 4.2 0.0 2.9 2 1 1 3 3 3 0 Adaptin N terminal region HEAT_EZ PF13513.6 KKK24715.1 - 0.041 14.4 4.7 11 6.7 0.0 5.0 5 1 1 6 6 6 0 HEAT-like repeat V-ATPase_H_C PF11698.8 KKK24715.1 - 0.046 13.8 0.0 1.9 8.6 0.0 2.4 2 0 0 2 2 2 0 V-ATPase subunit H Cnd1 PF12717.7 KKK24715.1 - 0.059 13.4 0.1 0.18 11.8 0.0 1.8 2 1 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 DRIM PF07539.12 KKK24715.1 - 0.06 11.6 1.9 2.2 6.5 1.0 2.4 1 1 1 2 2 2 0 Down-regulated in metastasis Vac14_Fab1_bd PF12755.7 KKK24715.1 - 0.11 13.2 0.0 0.31 11.7 0.0 1.8 1 0 0 1 1 1 0 Vacuolar 14 Fab1-binding region OPT PF03169.15 KKK24716.1 - 2.3e-171 571.5 55.6 2.6e-171 571.4 55.6 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DAO PF01266.24 KKK24718.1 - 1e-28 101.0 0.0 1.2e-28 100.7 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase ApbA PF02558.16 KKK24718.1 - 0.06 13.0 1.1 0.11 12.2 1.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DUF604 PF04646.12 KKK24718.1 - 0.15 11.4 0.4 0.24 10.8 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF604 Pyr_redox_2 PF07992.14 KKK24718.1 - 0.17 11.1 0.1 0.26 10.5 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Sugar_tr PF00083.24 KKK24719.1 - 1.5e-116 389.9 19.5 1.8e-116 389.7 19.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKK24719.1 - 9e-26 90.6 48.6 4.9e-25 88.2 22.3 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KKK24719.1 - 0.0058 15.1 1.1 0.0058 15.1 1.1 1.9 3 0 0 3 3 3 1 Fungal trichothecene efflux pump (TRI12) DUF2530 PF10745.9 KKK24719.1 - 0.13 12.5 1.7 0.84 9.9 1.7 2.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2530) Phage_holin_2_3 PF16080.5 KKK24719.1 - 0.16 11.7 0.1 0.16 11.7 0.1 2.9 3 0 0 3 3 3 0 Bacteriophage holin family HP1 Transglut_core PF01841.19 KKK24720.1 - 1.2e-11 45.0 0.0 2.1e-11 44.3 0.0 1.3 1 0 0 1 1 1 1 Transglutaminase-like superfamily Gln_amidase PF15644.6 KKK24720.1 - 0.019 16.0 0.0 0.051 14.6 0.0 1.8 1 0 0 1 1 1 0 Papain fold toxin 1, glutamine deamidase TRAM_LAG1_CLN8 PF03798.16 KKK24721.1 - 3.5e-39 134.6 19.7 3.5e-39 134.6 19.7 1.6 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.11 KKK24721.1 - 4.2e-22 77.6 1.4 6.5e-22 77.0 0.0 2.1 2 0 0 2 2 2 1 TRAM1-like protein Thioredoxin_4 PF13462.6 KKK24721.1 - 0.11 12.6 0.1 0.18 11.9 0.1 1.3 1 0 0 1 1 1 0 Thioredoxin DUF4470 PF14737.6 KKK24722.1 - 3.7e-27 94.4 0.1 7.8e-27 93.3 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) Apc13p PF05839.11 KKK24723.1 - 0.059 13.6 0.2 6 7.1 0.2 3.1 2 0 0 2 2 2 0 Apc13p protein DTHCT PF08070.11 KKK24723.1 - 0.16 12.7 0.1 0.16 12.7 0.1 3.8 4 0 0 4 4 4 0 DTHCT (NUC029) region Clathrin PF00637.20 KKK24724.1 - 9.9e-24 83.8 4.7 6.9e-21 74.6 2.9 2.6 2 0 0 2 2 2 2 Region in Clathrin and VPS VPS11_C PF12451.8 KKK24724.1 - 4e-19 68.6 0.9 9.5e-19 67.4 0.9 1.7 1 0 0 1 1 1 1 Vacuolar protein sorting protein 11 C terminal zf-C3H2C3 PF17122.5 KKK24724.1 - 2.9e-07 30.4 4.2 5.7e-07 29.5 4.2 1.5 1 0 0 1 1 1 1 Zinc-finger zf-C3HC4_2 PF13923.6 KKK24724.1 - 5e-06 26.3 3.6 1e-05 25.2 3.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) TPR_14 PF13428.6 KKK24724.1 - 0.00023 21.7 0.2 0.074 13.9 0.0 3.6 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 KKK24724.1 - 0.00053 19.6 0.1 0.0022 17.6 0.1 2.1 1 0 0 1 1 1 1 TPR repeat zf-RING_2 PF13639.6 KKK24724.1 - 0.0018 18.5 6.0 0.0037 17.6 6.0 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 KKK24724.1 - 0.0095 16.2 4.2 0.019 15.2 4.2 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain DUF4810 PF16068.5 KKK24724.1 - 0.012 16.2 0.7 3.9 8.1 0.0 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4810) zf-C3HC4 PF00097.25 KKK24724.1 - 0.016 15.1 2.6 0.033 14.1 2.6 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KKK24724.1 - 0.016 15.1 5.1 0.034 14.1 5.1 1.5 1 0 0 1 1 1 0 zinc-RING finger domain TPR_16 PF13432.6 KKK24724.1 - 0.041 14.5 0.7 0.13 12.9 0.1 2.2 3 0 0 3 3 1 0 Tetratricopeptide repeat CdiI_2 PF18593.1 KKK24724.1 - 0.14 12.8 0.9 26 5.6 0.0 3.6 3 0 0 3 3 3 0 CdiI immunity protein zf-RING-like PF08746.11 KKK24724.1 - 0.31 11.4 2.8 0.68 10.3 2.8 1.5 1 0 0 1 1 1 0 RING-like domain zf-ANAPC11 PF12861.7 KKK24724.1 - 0.38 10.8 1.4 0.82 9.8 1.4 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 KKK24724.1 - 0.62 10.1 3.4 1.6 8.8 3.4 1.6 1 0 0 1 1 1 0 RING-type zinc-finger Vps39_1 PF10366.9 KKK24724.1 - 0.79 10.0 3.7 3.2 8.1 1.6 2.9 2 1 1 3 3 3 0 Vacuolar sorting protein 39 domain 1 ANAPC3 PF12895.7 KKK24724.1 - 1.4 9.2 6.8 4.1 7.7 0.4 3.2 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 KKK24724.1 - 1.7 8.6 4.2 3.1 7.8 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat eIF3_N PF09440.10 KKK24724.1 - 4.4 7.7 6.4 1.1 9.7 1.9 2.4 2 1 1 3 3 2 0 eIF3 subunit 6 N terminal domain TPR_2 PF07719.17 KKK24724.1 - 8.2 6.8 10.2 0.22 11.8 0.3 3.3 4 0 0 4 4 2 0 Tetratricopeptide repeat PORR PF11955.8 KKK24735.1 - 0.12 11.3 0.1 0.17 10.8 0.1 1.2 1 0 0 1 1 1 0 Plant organelle RNA recognition domain AMPK1_CBM PF16561.5 KKK24740.1 - 3.9e-18 65.4 1.5 7.6e-18 64.5 1.5 1.4 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase CBM_48 PF02922.18 KKK24740.1 - 0.011 16.1 0.1 0.026 14.9 0.1 1.6 1 0 0 1 1 1 0 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) CBM53 PF16760.5 KKK24740.1 - 0.076 13.6 1.2 0.18 12.4 1.2 1.7 1 0 0 1 1 1 0 Starch/carbohydrate-binding module (family 53) Macoilin PF09726.9 KKK24740.1 - 0.48 8.9 6.9 0.88 8.0 6.9 1.3 1 0 0 1 1 1 0 Macoilin family cNMP_binding PF00027.29 KKK24741.1 - 1.3e-40 137.4 0.0 4.1e-21 74.8 0.0 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain 2OG-FeII_Oxy_3 PF13640.6 KKK24742.1 - 3.3e-11 43.9 0.0 6e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Forkhead PF00250.18 KKK24743.1 - 2.4e-17 63.0 0.0 4.6e-17 62.0 0.0 1.4 1 0 0 1 1 1 1 Forkhead domain FHA PF00498.26 KKK24743.1 - 1.6e-05 25.2 0.0 2.9e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 FHA domain Dicty_REP PF05086.12 KKK24743.1 - 2.8 5.8 6.6 4 5.3 6.6 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Glyco_transf_20 PF00982.21 KKK24746.1 - 1.6e-149 498.6 0.0 2.1e-149 498.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 KKK24746.1 - 1.2e-82 276.6 0.0 1.6e-82 276.1 0.0 1.2 1 0 0 1 1 1 1 Trehalose-phosphatase Hydrolase_3 PF08282.12 KKK24746.1 - 0.0019 18.0 0.0 0.36 10.5 0.0 2.2 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase MFS_1 PF07690.16 KKK24747.1 - 2.4e-22 79.4 52.5 1.1e-17 64.0 39.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily PSI_8 PF00796.18 KKK24747.1 - 0.074 12.9 0.6 0.41 10.5 0.6 2.3 1 0 0 1 1 1 0 Photosystem I reaction centre subunit VIII PP28 PF10252.9 KKK24748.1 - 1.2e-29 102.6 9.2 1.2e-29 102.6 9.2 3.0 2 2 1 3 3 3 1 Casein kinase substrate phosphoprotein PP28 DNA_pol_phi PF04931.13 KKK24748.1 - 7.6 4.5 11.7 12 3.8 11.7 1.3 1 0 0 1 1 1 0 DNA polymerase phi PLDc PF00614.22 KKK24750.1 - 4.2e-15 55.2 0.2 2.7e-07 30.5 0.1 2.7 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 KKK24750.1 - 1e-12 48.1 0.1 2.4e-06 27.5 0.0 3.1 3 1 0 3 3 3 2 PLD-like domain PX PF00787.24 KKK24750.1 - 1.9e-07 31.1 0.2 8.2e-07 29.0 0.0 2.3 2 0 0 2 2 2 1 PX domain Fungal_trans PF04082.18 KKK24753.1 - 7.5e-24 84.2 0.0 1.1e-23 83.7 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Trimer_CC PF08954.11 KKK24753.1 - 0.33 10.5 4.5 0.26 10.9 0.3 2.6 2 0 0 2 2 2 0 Trimerisation motif MR_MLE_C PF13378.6 KKK24754.1 - 4e-40 137.7 0.0 5.2e-40 137.3 0.0 1.1 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 KKK24754.1 - 1.4e-10 41.4 0.0 2.4e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain L51_S25_CI-B8 PF05047.16 KKK24780.1 - 1.6e-20 72.8 0.0 2.4e-20 72.2 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain DUF1382 PF07131.11 KKK24780.1 - 0.58 10.2 3.4 4.7 7.3 1.7 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1382) DUF1751 PF08551.10 KKK24781.1 - 2.7e-30 104.8 4.2 5.1e-30 104.0 2.8 2.1 2 0 0 2 2 2 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.22 KKK24781.1 - 4.1e-06 26.9 9.4 7.2e-06 26.1 9.4 1.4 1 0 0 1 1 1 1 Rhomboid family DUF4149 PF13664.6 KKK24781.1 - 2 8.8 9.2 0.34 11.2 1.3 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4149) ANAPC4_WD40 PF12894.7 KKK24782.1 - 3.9e-08 33.5 1.5 2.5 8.5 0.0 5.4 3 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KKK24782.1 - 4.3e-07 30.5 12.5 0.063 14.2 0.1 6.8 7 0 0 7 7 7 2 WD domain, G-beta repeat LisH PF08513.11 KKK24782.1 - 1.4e-06 28.1 0.0 2.9e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 LisH eIF2A PF08662.11 KKK24782.1 - 0.00073 19.5 0.0 0.0027 17.6 0.0 2.0 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A RhoGEF PF00621.20 KKK24785.1 - 1.3e-22 81.0 0.0 2.8e-22 79.8 0.0 1.6 1 0 0 1 1 1 1 RhoGEF domain DUF3507 PF12015.8 KKK24785.1 - 2.3e-08 34.0 0.0 3.7e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3507) FAM184 PF15665.5 KKK24785.1 - 0.015 15.1 2.2 0.037 13.8 2.2 1.6 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B Cep57_CLD_2 PF14197.6 KKK24785.1 - 0.082 13.0 1.3 0.37 10.9 1.3 2.1 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 RhoGAP PF00620.27 KKK24785.1 - 0.091 12.6 0.2 12 5.7 0.0 2.7 2 0 0 2 2 2 0 RhoGAP domain ZapB PF06005.12 KKK24785.1 - 0.47 10.9 3.2 0.45 11.0 0.4 2.4 2 0 0 2 2 2 0 Cell division protein ZapB Sec7 PF01369.20 KKK24786.1 - 9.4e-61 204.7 0.0 1.6e-60 204.0 0.0 1.4 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 KKK24786.1 - 3.7e-17 62.7 0.0 1.1e-16 61.1 0.0 1.9 1 0 0 1 1 1 1 Guanine nucleotide exchange factor in Golgi transport N-terminal PUF PF00806.19 KKK24850.1 - 9e-54 176.3 2.5 3.2e-08 32.8 0.0 7.5 7 0 0 7 7 7 7 Pumilio-family RNA binding repeat ORC5_C PF14630.6 KKK24851.1 - 2.3e-84 283.3 0.0 3.3e-84 282.8 0.0 1.2 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_16 PF13191.6 KKK24851.1 - 3.4e-14 53.6 0.0 8.3e-14 52.3 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain WD40 PF00400.32 KKK24871.1 - 6.8e-40 134.3 27.5 3.4e-09 37.2 0.1 12.7 13 0 0 13 13 12 6 WD domain, G-beta repeat Utp12 PF04003.12 KKK24871.1 - 1.1e-26 93.2 0.0 1.8e-26 92.6 0.0 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 KKK24871.1 - 2.7e-21 75.7 0.0 0.001 19.3 0.0 9.6 4 2 5 11 11 11 7 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KKK24871.1 - 4.6e-10 39.0 0.4 0.13 11.2 0.0 4.5 2 2 2 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KKK24871.1 - 1.4e-06 28.3 0.2 0.004 17.0 0.2 4.9 5 1 1 6 6 6 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KKK24871.1 - 1.5e-05 23.9 5.1 0.77 8.3 0.0 5.1 2 2 2 4 4 4 2 Nucleoporin Nup120/160 PD40 PF07676.12 KKK24871.1 - 0.0042 17.0 0.1 31 4.7 0.0 5.4 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat PQQ_3 PF13570.6 KKK24871.1 - 0.025 15.1 3.3 22 5.7 0.2 5.1 5 0 0 5 5 5 0 PQQ-like domain Nbas_N PF15492.6 KKK24871.1 - 0.035 13.4 0.1 12 5.1 0.0 3.3 3 1 0 3 3 3 0 Neuroblastoma-amplified sequence, N terminal WD40_like PF17005.5 KKK24871.1 - 0.049 13.0 0.1 0.95 8.7 0.0 2.9 3 0 0 3 3 3 0 WD40-like domain DUF1513 PF07433.11 KKK24871.1 - 0.072 12.2 0.6 1.3 8.0 0.0 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1513) PQQ PF01011.21 KKK24871.1 - 0.23 11.5 0.5 5.4 7.1 0.0 3.5 4 0 0 4 4 4 0 PQQ enzyme repeat Septin PF00735.18 KKK24872.1 - 2e-70 237.3 0.1 2.4e-70 237.0 0.1 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 KKK24872.1 - 1.1e-07 31.9 0.0 1.5e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KKK24872.1 - 8.2e-07 28.8 0.5 7.4e-06 25.6 0.2 2.0 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KKK24872.1 - 3.2e-06 27.2 0.1 2.6e-05 24.2 0.1 2.2 2 1 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 KKK24872.1 - 0.0003 21.1 0.1 0.00071 19.9 0.1 1.6 1 1 0 1 1 1 1 AAA domain Pox_A32 PF04665.12 KKK24872.1 - 0.0017 17.9 0.1 0.0026 17.3 0.1 1.2 1 0 0 1 1 1 1 Poxvirus A32 protein Roc PF08477.13 KKK24872.1 - 0.0031 17.7 0.1 0.0047 17.1 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase IIGP PF05049.13 KKK24872.1 - 0.0039 16.3 0.0 0.005 15.9 0.0 1.2 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) AIG1 PF04548.16 KKK24872.1 - 0.0051 16.2 0.0 0.0064 15.8 0.0 1.2 1 0 0 1 1 1 1 AIG1 family AAA_24 PF13479.6 KKK24872.1 - 0.0091 15.7 0.5 0.013 15.2 0.5 1.4 1 1 0 1 1 1 1 AAA domain Dynamin_N PF00350.23 KKK24872.1 - 0.01 15.9 0.6 1.7 8.7 0.1 2.2 1 1 1 2 2 2 0 Dynamin family AAA_16 PF13191.6 KKK24872.1 - 0.019 15.4 0.0 0.021 15.2 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain PduV-EutP PF10662.9 KKK24872.1 - 0.022 14.5 0.4 1.7 8.4 0.4 2.4 2 1 0 2 2 1 0 Ethanolamine utilisation - propanediol utilisation Ras PF00071.22 KKK24872.1 - 0.022 14.3 0.5 0.048 13.3 0.5 1.5 1 1 0 1 1 1 0 Ras family NACHT PF05729.12 KKK24872.1 - 0.025 14.5 0.0 0.04 13.8 0.0 1.3 1 0 0 1 1 1 0 NACHT domain KAP_NTPase PF07693.14 KKK24872.1 - 0.028 13.7 0.0 0.028 13.7 0.0 1.1 1 0 0 1 1 1 0 KAP family P-loop domain ABC_tran PF00005.27 KKK24872.1 - 0.036 14.6 0.0 0.049 14.2 0.0 1.3 1 0 0 1 1 1 0 ABC transporter ATP_bind_1 PF03029.17 KKK24872.1 - 0.045 13.5 0.2 5.5 6.7 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Sigma54_activat PF00158.26 KKK24872.1 - 0.058 13.1 0.0 0.087 12.5 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain T2SSE PF00437.20 KKK24872.1 - 0.062 12.3 0.1 0.1 11.7 0.1 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.18 KKK24872.1 - 0.087 12.2 0.1 0.14 11.5 0.1 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family RNA_helicase PF00910.22 KKK24872.1 - 0.091 13.2 0.0 0.18 12.2 0.0 1.6 1 0 0 1 1 1 0 RNA helicase FeoB_N PF02421.18 KKK24872.1 - 0.18 11.3 0.1 0.64 9.5 0.1 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B HMG_box PF00505.19 KKK24882.1 - 2.6e-21 75.8 0.9 4.7e-21 75.0 0.9 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KKK24882.1 - 1.2e-06 29.0 0.1 2.8e-06 27.8 0.1 1.6 1 0 0 1 1 1 1 HMG-box domain BEX PF04538.12 KKK24882.1 - 0.072 13.7 1.9 0.11 13.2 1.9 1.3 1 0 0 1 1 1 0 Brain expressed X-linked like family SAICAR_synt PF01259.18 KKK24883.1 - 1.5e-97 326.2 0.0 1.7e-97 325.9 0.0 1.0 1 0 0 1 1 1 1 SAICAR synthetase RhoGAP PF00620.27 KKK24884.1 - 5.9e-48 162.5 0.0 2.5e-47 160.5 0.0 2.0 2 0 0 2 2 2 1 RhoGAP domain FCH PF00611.23 KKK24884.1 - 6.4e-12 45.6 2.0 2.4e-11 43.7 0.1 2.6 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain V-ATPase_G_2 PF16999.5 KKK24884.1 - 0.49 10.8 10.6 1.2 9.6 3.5 2.5 2 0 0 2 2 2 0 Vacuolar (H+)-ATPase G subunit OmpH PF03938.14 KKK24884.1 - 2.9 8.2 8.7 9.2 6.6 7.7 2.3 2 1 0 2 2 2 0 Outer membrane protein (OmpH-like) Alanine_zipper PF11839.8 KKK24884.1 - 3.3 8.2 7.3 1.1 9.7 0.5 2.7 3 0 0 3 3 3 0 Alanine-zipper, major outer membrane lipoprotein DUF953 PF06110.11 KKK24885.1 - 5.5e-14 51.8 0.0 6.3e-14 51.6 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Thioredoxin_9 PF14595.6 KKK24885.1 - 0.00015 21.5 0.0 0.0002 21.2 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin HyaE PF07449.11 KKK24885.1 - 0.0027 17.6 0.0 0.0048 16.8 0.0 1.5 1 1 0 1 1 1 1 Hydrogenase-1 expression protein HyaE Peptidase_M49 PF03571.15 KKK24886.1 - 2.2e-166 554.5 0.0 2.5e-166 554.3 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M49 MFS_1 PF07690.16 KKK24888.1 - 5.7e-39 134.0 33.9 5.7e-39 134.0 33.9 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KKK24888.1 - 2.7e-15 55.9 15.8 4.8e-15 55.0 15.8 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KKK24888.1 - 2.3e-12 46.6 15.5 2.3e-12 46.6 15.5 2.6 2 1 1 3 3 3 1 Sugar (and other) transporter DSBA PF01323.20 KKK24889.1 - 1.1e-13 51.4 0.0 1.3e-13 51.2 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Glyco_hydro_18 PF00704.28 KKK24890.1 - 3.8e-74 250.2 0.0 5e-74 249.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 KKK24890.1 - 9.5e-09 35.6 16.6 2e-08 34.6 16.6 1.5 1 0 0 1 1 1 1 Chitin recognition protein ANTH PF07651.16 KKK24892.1 - 9.6e-72 241.3 0.0 9.6e-72 241.3 0.0 3.0 2 1 0 3 3 3 1 ANTH domain I_LWEQ PF01608.17 KKK24892.1 - 4.8e-56 189.3 9.9 4.8e-56 189.3 9.9 5.9 3 2 2 5 5 5 2 I/LWEQ domain COX6A PF02046.15 KKK24893.1 - 2e-46 157.1 0.3 2.5e-46 156.7 0.3 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa RRM_1 PF00076.22 KKK24895.1 - 0.00036 20.3 0.0 0.00067 19.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Fungal_trans PF04082.18 KKK24896.1 - 8.7e-18 64.3 0.0 1.6e-17 63.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK24896.1 - 2.8e-06 27.3 9.4 4.9e-06 26.6 9.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain V-SNARE PF05008.15 KKK24896.1 - 0.12 12.7 0.2 0.32 11.4 0.1 1.7 2 0 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus UPF0139 PF03669.13 KKK24897.1 - 5.2e-06 26.2 0.3 7.5e-06 25.7 0.3 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0139) Med12 PF09497.10 KKK24898.1 - 1.1e-27 96.0 0.8 1.1e-27 96.0 0.8 2.1 2 0 0 2 2 2 1 Transcription mediator complex subunit Med12 EOS1 PF12326.8 KKK24899.1 - 3.7e-12 46.5 9.2 3.7e-12 46.5 9.2 2.0 1 1 1 2 2 2 1 N-glycosylation protein SUI1 PF01253.22 KKK24900.1 - 2.5e-28 98.4 3.9 3.3e-28 98.0 3.9 1.2 1 0 0 1 1 1 1 Translation initiation factor SUI1 GlcNAc-1_reg PF18440.1 KKK24900.1 - 0.048 13.9 0.4 0.077 13.2 0.4 1.3 1 0 0 1 1 1 0 Putative GlcNAc-1 phosphotransferase regulatory domain MBA1 PF07961.11 KKK24901.1 - 0.02 14.0 0.0 0.036 13.1 0.0 1.4 1 1 0 1 1 1 0 MBA1-like protein Ras PF00071.22 KKK24902.1 - 3.2e-55 186.2 0.0 3.6e-55 186.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KKK24902.1 - 3e-21 75.9 0.0 4.3e-21 75.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKK24902.1 - 2.9e-07 30.1 0.0 3.7e-07 29.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Fungal_trans PF04082.18 KKK24903.1 - 0.00026 20.1 0.6 0.00038 19.6 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK24903.1 - 0.014 15.5 1.6 0.014 15.5 1.6 1.8 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1730 PF08331.10 KKK24904.1 - 0.61 10.0 2.3 0.9 9.5 0.3 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF1730) FAD_binding_3 PF01494.19 KKK24905.1 - 2.2e-84 283.7 0.2 2.8e-84 283.4 0.2 1.1 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KKK24905.1 - 3.3e-05 24.0 0.1 0.00029 21.0 0.1 2.6 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KKK24905.1 - 3.7e-05 23.5 4.9 0.00027 20.6 0.9 2.3 1 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KKK24905.1 - 0.00012 21.3 0.1 0.00021 20.5 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 KKK24905.1 - 0.0006 19.1 0.1 0.0011 18.2 0.1 1.4 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 KKK24905.1 - 0.00064 18.5 0.2 0.0012 17.6 0.2 1.4 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.6 KKK24905.1 - 0.0011 18.3 0.2 0.0021 17.4 0.2 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KKK24905.1 - 0.0012 18.2 0.2 0.0024 17.2 0.2 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KKK24905.1 - 0.0019 17.3 0.1 0.0046 16.1 0.1 1.6 1 0 0 1 1 1 1 Lycopene cyclase protein Trp_halogenase PF04820.14 KKK24905.1 - 0.003 16.5 0.0 0.0054 15.6 0.0 1.4 1 0 0 1 1 1 1 Tryptophan halogenase SE PF08491.10 KKK24905.1 - 0.018 14.1 0.0 0.052 12.6 0.0 1.8 1 1 0 1 1 1 0 Squalene epoxidase Clp_N PF02861.20 KKK24905.1 - 0.11 12.6 0.1 0.29 11.3 0.1 1.6 1 0 0 1 1 1 0 Clp amino terminal domain, pathogenicity island component NAD_binding_9 PF13454.6 KKK24905.1 - 0.13 12.2 1.0 0.4 10.7 0.1 2.3 3 0 0 3 3 2 0 FAD-NAD(P)-binding Pyr_redox PF00070.27 KKK24905.1 - 0.19 12.3 1.4 1.1 9.9 0.1 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase RRM_1 PF00076.22 KKK24906.1 - 4.2e-15 55.3 0.0 9.4e-15 54.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Asp-B-Hydro_N PF05279.11 KKK24906.1 - 2.4 8.2 56.1 2.7 8.0 51.1 2.1 2 0 0 2 2 2 0 Aspartyl beta-hydroxylase N-terminal region UBX PF00789.20 KKK24907.1 - 2e-09 37.5 0.0 4.1e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 UBX domain ABC2_membrane PF01061.24 KKK24908.1 - 4.5e-77 258.2 61.0 5.8e-40 137.0 20.2 3.5 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.27 KKK24908.1 - 9.1e-37 126.6 0.0 1.8e-17 64.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 KKK24908.1 - 2.4e-36 123.5 12.0 7.4e-34 115.5 0.4 4.0 3 0 0 3 3 3 2 CDR ABC transporter ABC_trans_N PF14510.6 KKK24908.1 - 2.8e-16 59.9 0.1 6.3e-16 58.8 0.1 1.7 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_16 PF13191.6 KKK24908.1 - 1.6e-06 28.7 0.6 0.0013 19.2 0.3 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.6 KKK24908.1 - 2e-06 27.5 0.1 3.9e-05 23.3 0.0 2.5 3 0 0 3 3 3 1 AAA domain RsgA_GTPase PF03193.16 KKK24908.1 - 5.3e-06 26.4 0.1 0.0027 17.6 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 KKK24908.1 - 0.00032 20.4 1.8 0.026 14.2 0.2 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_18 PF13238.6 KKK24908.1 - 0.0016 19.0 0.0 0.055 14.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KKK24908.1 - 0.0032 17.4 0.8 2.5 8.0 0.1 2.7 2 0 0 2 2 2 2 NACHT domain AAA_22 PF13401.6 KKK24908.1 - 0.0055 17.0 1.6 1.5 9.1 0.4 2.7 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KKK24908.1 - 0.0078 16.4 1.9 0.022 14.9 0.1 2.3 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KKK24908.1 - 0.0094 15.7 0.4 1.7 8.3 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 KKK24908.1 - 0.014 15.2 0.8 3.8 7.2 0.1 3.0 2 1 1 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 KKK24908.1 - 0.042 13.9 0.1 6.8 6.8 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_17 PF13207.6 KKK24908.1 - 0.054 13.9 0.4 6.1 7.3 0.0 2.6 2 1 0 2 2 2 0 AAA domain cobW PF02492.19 KKK24908.1 - 0.058 13.0 1.0 1.4 8.4 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain IstB_IS21 PF01695.17 KKK24908.1 - 0.12 12.1 0.1 1.4 8.6 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA PF00004.29 KKK24908.1 - 0.17 12.3 0.1 31 5.0 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) SMC_N PF02463.19 KKK24908.1 - 0.18 11.2 0.0 29 4.0 0.0 3.3 3 1 0 3 3 3 0 RecF/RecN/SMC N terminal domain PDR_assoc PF08370.11 KKK24908.1 - 0.59 9.9 4.8 0.18 11.5 0.4 2.5 2 0 0 2 2 2 0 Plant PDR ABC transporter associated Fungal_trans PF04082.18 KKK24909.1 - 3.9e-16 58.9 0.1 5.2e-16 58.5 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain CMS1 PF14617.6 KKK24910.1 - 1.2e-57 195.1 7.6 3.1e-57 193.8 7.6 1.8 1 1 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.29 KKK24910.1 - 7.2e-06 25.9 0.0 8.1e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase H-K_ATPase_N PF09040.11 KKK24910.1 - 0.38 11.2 7.3 9.5 6.8 3.2 3.1 3 0 0 3 3 3 0 Gastric H+/K+-ATPase, N terminal domain Dicty_REP PF05086.12 KKK24910.1 - 0.41 8.6 1.4 0.5 8.3 1.4 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein CENP-T_C PF15511.6 KKK24911.1 - 3.4e-45 152.6 0.1 5.1e-45 152.0 0.1 1.3 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 KKK24911.1 - 7.5e-09 35.9 0.1 1.3e-08 35.1 0.1 1.4 1 0 0 1 1 1 1 CENP-S protein Histone PF00125.24 KKK24911.1 - 0.00026 21.4 0.0 0.00055 20.3 0.0 1.6 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 DUF531 PF04407.12 KKK24911.1 - 0.043 13.9 0.0 0.067 13.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF531) CBFD_NFYB_HMF PF00808.23 KKK24911.1 - 0.11 12.8 0.0 0.18 12.1 0.0 1.4 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone SURF1 PF02104.15 KKK24912.1 - 9e-48 162.8 0.0 1.3e-47 162.3 0.0 1.2 1 0 0 1 1 1 1 SURF1 family DUF2076 PF09849.9 KKK24913.1 - 1.4e-09 38.4 12.7 1.7e-09 38.1 12.7 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.13 KKK24913.1 - 0.00013 22.0 2.8 0.00023 21.2 2.5 1.6 1 1 1 2 2 2 2 CHCH domain CX9C PF16860.5 KKK24913.1 - 0.021 14.8 0.7 0.033 14.2 0.7 1.3 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, GAGE PF05831.11 KKK24913.1 - 6.1 7.4 8.9 2.1 8.9 0.1 2.2 2 0 0 2 2 2 0 GAGE protein CIA30 PF08547.12 KKK24914.1 - 6.4e-40 136.8 0.0 1.4e-26 93.4 0.0 2.1 2 0 0 2 2 2 2 Complex I intermediate-associated protein 30 (CIA30) Sugar_tr PF00083.24 KKK24915.1 - 2e-99 333.5 15.8 2.3e-99 333.3 15.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKK24915.1 - 8.7e-19 67.6 31.5 4.1e-15 55.5 7.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Phage_holin_3_2 PF04550.12 KKK24915.1 - 0.0078 16.7 0.2 0.025 15.1 0.2 1.8 1 0 0 1 1 1 1 Phage holin family 2 ANAPC5 PF12862.7 KKK24916.1 - 1.8e-36 124.1 5.1 4.5e-36 122.8 2.2 2.5 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 5 TPR_12 PF13424.6 KKK24916.1 - 0.018 15.3 7.8 4.3 7.7 0.1 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF627 PF04781.12 KKK24916.1 - 0.047 13.7 0.1 0.36 10.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF627) TPR_2 PF07719.17 KKK24916.1 - 0.053 13.7 1.0 30 5.1 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 KKK24916.1 - 0.053 13.4 0.8 0.24 11.3 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Exo_endo_phos PF03372.23 KKK24917.1 - 2e-13 50.4 0.2 3.2e-13 49.7 0.2 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 KKK24917.1 - 0.0027 17.5 0.0 2.8 7.8 0.0 2.5 2 0 0 2 2 2 2 Endonuclease-reverse transcriptase zf-GRF PF06839.12 KKK24917.1 - 0.0078 16.3 1.2 0.019 15.1 1.2 1.7 1 0 0 1 1 1 1 GRF zinc finger Hamartin PF04388.12 KKK24917.1 - 2.5 6.7 9.8 3.3 6.3 9.8 1.1 1 0 0 1 1 1 0 Hamartin protein adh_short_C2 PF13561.6 KKK24918.1 - 2.4e-53 181.1 1.1 3e-53 180.8 1.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KKK24918.1 - 4.8e-44 150.2 6.0 8.1e-44 149.4 5.2 1.7 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 KKK24918.1 - 5.5e-09 36.2 3.5 1.7e-08 34.6 3.5 1.7 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KKK24918.1 - 0.0045 16.5 0.7 0.02 14.4 0.7 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF4314 PF14192.6 KKK24918.1 - 0.057 13.3 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4314) Zn_clus PF00172.18 KKK24919.1 - 1.3e-05 25.2 14.2 3.1e-05 24.0 14.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Trp_syntA PF00290.20 KKK24920.1 - 3.9e-93 311.0 0.0 6.7e-93 310.3 0.0 1.3 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.25 KKK24920.1 - 1.9e-44 152.3 0.6 3.3e-44 151.5 0.6 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Malic_M PF03949.15 KKK24925.1 - 1.6e-91 306.2 0.0 2e-91 305.8 0.0 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 KKK24925.1 - 9e-47 159.2 0.0 2.3e-36 125.3 0.0 2.3 1 1 1 2 2 2 2 Malic enzyme, N-terminal domain zf-C2H2 PF00096.26 KKK24954.1 - 0.019 15.4 1.7 0.62 10.6 0.1 3.2 2 0 0 2 2 2 0 Zinc finger, C2H2 type DUF3500 PF12006.8 KKK24955.1 - 2.3e-110 368.8 0.0 3.2e-110 368.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3500) adh_short PF00106.25 KKK24955.1 - 6.4e-27 94.3 0.1 5.4e-20 71.7 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KKK24955.1 - 9e-14 51.6 0.0 3.6e-12 46.3 0.0 2.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KKK24955.1 - 1.7e-07 31.4 0.0 3.4e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 KKK24956.1 - 5.2e-50 170.2 0.0 3.2e-48 164.3 0.0 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KKK24956.1 - 1.4e-38 132.3 0.4 1e-36 126.2 0.4 2.0 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KKK24956.1 - 3.1e-07 30.5 0.2 5e-06 26.6 0.2 2.1 1 1 0 1 1 1 1 KR domain UPF0160 PF03690.13 KKK24957.1 - 1.8e-125 418.8 0.0 2e-125 418.6 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) CTP_synth_N PF06418.14 KKK24958.1 - 4e-121 403.4 0.1 5.2e-121 403.0 0.1 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 KKK24958.1 - 2.9e-53 180.5 0.0 6.4e-53 179.4 0.0 1.6 2 0 0 2 2 2 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 KKK24958.1 - 9.5e-05 22.2 0.2 0.00062 19.6 0.2 2.3 2 1 0 2 2 2 1 Peptidase C26 CbiA PF01656.23 KKK24958.1 - 0.082 13.0 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain DUF3535 PF12054.8 KKK24959.1 - 6.3e-113 378.3 0.0 9.4e-112 374.4 0.0 2.9 3 1 0 3 3 3 1 Domain of unknown function (DUF3535) SNF2_N PF00176.23 KKK24959.1 - 2.8e-62 210.5 0.0 6.3e-62 209.3 0.0 1.5 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KKK24959.1 - 1.2e-19 70.7 0.0 2.9e-19 69.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HEAT PF02985.22 KKK24959.1 - 1.3e-15 56.1 15.9 0.13 12.6 0.0 11.2 14 0 0 14 14 12 5 HEAT repeat HEAT_2 PF13646.6 KKK24959.1 - 2.6e-07 30.9 9.3 0.00069 20.0 0.1 6.6 6 1 1 7 7 7 1 HEAT repeats Vac14_Fab1_bd PF12755.7 KKK24959.1 - 4.5e-07 30.4 0.1 0.037 14.6 0.0 4.0 3 1 0 4 4 4 2 Vacuolar 14 Fab1-binding region TAF6_C PF07571.13 KKK24959.1 - 2.8e-05 24.3 0.0 0.82 10.0 0.0 5.5 6 0 0 6 6 6 1 TAF6 C-terminal HEAT repeat domain Cnd1 PF12717.7 KKK24959.1 - 0.0001 22.4 0.2 0.33 11.0 0.0 5.0 5 0 0 5 5 5 1 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 KKK24959.1 - 0.057 13.0 0.1 12 5.3 0.0 3.6 2 1 1 3 3 3 0 CLASP N terminal HEAT_EZ PF13513.6 KKK24959.1 - 0.32 11.6 17.6 28 5.3 0.3 7.7 8 0 0 8 8 8 0 HEAT-like repeat U3_snoRNA_assoc PF08297.11 KKK24959.1 - 3.4 8.4 5.5 0.96 10.2 0.6 2.6 2 0 0 2 2 2 0 U3 snoRNA associated HEAT_PBS PF03130.16 KKK24959.1 - 9 7.3 7.3 75 4.4 0.0 5.3 5 0 0 5 5 4 0 PBS lyase HEAT-like repeat TPR_11 PF13414.6 KKK24960.1 - 0.002 17.8 5.0 0.0031 17.2 2.2 2.8 3 0 0 3 3 3 1 TPR repeat ChAPs PF09295.10 KKK24961.1 - 2.2e-154 514.3 0.0 2.8e-154 513.9 0.0 1.1 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_14 PF13428.6 KKK24961.1 - 0.00015 22.3 3.0 0.3 12.0 0.0 4.7 3 3 2 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 KKK24961.1 - 0.00022 21.1 1.2 0.33 11.2 0.1 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 KKK24961.1 - 0.00029 20.5 0.1 4.3 7.3 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 KKK24961.1 - 0.0025 18.3 0.3 0.22 12.0 0.0 3.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 KKK24961.1 - 0.0066 16.6 0.0 6.8 7.2 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_15 PF13429.6 KKK24961.1 - 0.0099 15.1 0.6 1.8 7.7 0.1 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.6 KKK24961.1 - 0.041 14.0 0.3 4.3 7.5 0.0 3.0 2 1 1 3 3 3 0 Tetratricopeptide repeat DUF4129 PF13559.6 KKK24961.1 - 0.11 12.8 0.2 5 7.5 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4129) UQ_con PF00179.26 KKK24962.1 - 3.1e-42 143.5 0.0 3.5e-42 143.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KKK24962.1 - 8.5e-07 28.7 0.0 1e-06 28.5 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 KKK24962.1 - 0.018 14.9 0.0 0.028 14.3 0.0 1.3 1 0 0 1 1 1 0 UEV domain RWD PF05773.22 KKK24962.1 - 0.048 13.9 0.1 0.076 13.3 0.1 1.5 1 1 0 1 1 1 0 RWD domain Prok-E2_A PF14457.6 KKK24962.1 - 0.11 12.1 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family A Peptidase_S24 PF00717.23 KKK24963.1 - 2.7e-07 30.4 0.0 4.4e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like Zn_clus PF00172.18 KKK24964.1 - 1.6e-06 28.1 10.2 2.6e-06 27.4 10.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KKK24964.1 - 1.1e-05 24.7 0.3 2.9e-05 23.2 0.3 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain DUF3072 PF11272.8 KKK24964.1 - 0.053 13.4 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3072) ERCC4 PF02732.15 KKK24965.1 - 1.1e-27 97.2 0.0 1.7e-27 96.6 0.0 1.3 1 0 0 1 1 1 1 ERCC4 domain Epimerase PF01370.21 KKK24965.1 - 1.6e-14 53.9 0.0 2.8e-14 53.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KKK24965.1 - 2e-06 27.4 0.0 4.3e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KKK24965.1 - 4e-06 26.1 0.0 1.2e-05 24.4 0.0 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KKK24965.1 - 0.00047 19.4 0.0 0.26 10.4 0.0 2.4 2 0 0 2 2 2 2 Male sterility protein Ldh_1_N PF00056.23 KKK24965.1 - 0.01 15.9 0.0 0.018 15.1 0.0 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain NAD_binding_10 PF13460.6 KKK24965.1 - 0.055 13.4 0.1 0.1 12.5 0.1 1.4 1 0 0 1 1 1 0 NAD(P)H-binding Polysacc_synt_2 PF02719.15 KKK24965.1 - 0.13 11.3 0.0 0.47 9.5 0.0 1.8 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein E1-E2_ATPase PF00122.20 KKK24968.1 - 5.8e-50 169.3 0.0 4.6e-49 166.4 0.0 2.2 2 0 0 2 2 2 1 E1-E2 ATPase HMA PF00403.26 KKK24968.1 - 8.6e-47 157.4 2.2 4.5e-11 43.0 0.0 4.4 4 0 0 4 4 4 4 Heavy-metal-associated domain Hydrolase PF00702.26 KKK24968.1 - 1.4e-33 117.0 0.0 2.2e-33 116.3 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KKK24968.1 - 1.1e-05 25.3 0.0 0.0069 16.2 0.0 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 KKK24968.1 - 0.00012 22.6 0.0 0.0011 19.4 0.0 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase PRIMA1 PF16101.5 KKK24968.1 - 9.2 6.3 6.3 14 5.7 0.9 2.7 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 Sugar_tr PF00083.24 KKK24969.1 - 1e-77 262.0 18.9 1.4e-77 261.4 18.9 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter TFIIB PF00382.19 KKK24969.1 - 2.1e-32 111.0 0.8 2.6e-17 62.6 0.1 2.6 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.13 KKK24969.1 - 1.2e-26 93.0 1.7 3.8e-26 91.4 0.0 2.7 2 0 0 2 2 2 1 Brf1-like TBP-binding domain MFS_1 PF07690.16 KKK24969.1 - 5.5e-19 68.3 17.2 5.5e-19 68.3 17.2 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily TF_Zn_Ribbon PF08271.12 KKK24969.1 - 0.00054 19.4 3.7 0.00059 19.3 2.0 2.0 2 0 0 2 2 2 1 TFIIB zinc-binding Cyclin_N PF00134.23 KKK24969.1 - 0.0021 17.8 0.1 2.1 8.1 0.0 2.3 2 0 0 2 2 2 2 Cyclin, N-terminal domain IBR PF01485.21 KKK24969.1 - 0.16 12.3 1.3 0.35 11.1 1.3 1.5 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain GtrA PF04138.14 KKK24969.1 - 1.1 9.5 6.9 1.3 9.3 0.0 3.4 3 1 0 3 3 3 0 GtrA-like protein TPT PF03151.16 KKK24970.1 - 2.5e-24 86.1 27.8 3.3e-24 85.7 27.8 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 KKK24970.1 - 0.84 8.8 28.5 1.7 7.8 28.5 1.4 1 1 0 1 1 1 0 UAA transporter family DUF4131 PF13567.6 KKK24970.1 - 1.7 8.3 6.9 1.2e+02 2.3 0.0 4.1 3 1 0 3 3 3 0 Domain of unknown function (DUF4131) CbtB PF09489.10 KKK24970.1 - 4.9 7.3 7.7 2 8.6 0.1 3.0 3 0 0 3 3 3 0 Probable cobalt transporter subunit (CbtB) RTA1 PF04479.13 KKK24971.1 - 4.6e-39 134.2 5.0 5.9e-39 133.8 5.0 1.1 1 0 0 1 1 1 1 RTA1 like protein DUF3995 PF13160.6 KKK24971.1 - 0.87 10.0 6.0 0.18 12.2 0.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3995) Kinesin PF00225.23 KKK24972.1 - 8.8e-58 195.8 0.0 1.4e-57 195.2 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KKK24972.1 - 1.4e-11 44.6 0.0 8.4e-10 38.8 0.0 2.4 2 0 0 2 2 2 1 Microtubule binding KLRAQ PF10205.9 KKK24972.1 - 0.0055 16.9 0.9 0.0055 16.9 0.9 2.5 1 1 1 2 2 2 1 Predicted coiled-coil domain-containing protein Mto2_bdg PF12808.7 KKK24972.1 - 0.13 12.6 7.2 6.3 7.2 3.2 3.4 2 1 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region SIKE PF05769.11 KKK24972.1 - 0.27 11.2 10.6 0.79 9.6 10.6 1.7 1 1 0 1 1 1 0 SIKE family Pox_A_type_inc PF04508.12 KKK24972.1 - 0.44 10.5 7.6 0.076 12.9 2.2 2.7 2 1 1 3 3 3 0 Viral A-type inclusion protein repeat DivIC PF04977.15 KKK24972.1 - 2 8.3 6.6 22 4.9 0.2 2.8 2 0 0 2 2 2 0 Septum formation initiator KIAA1430 PF13879.6 KKK24972.1 - 2.6 8.9 6.8 5.6 7.8 2.0 2.7 2 1 0 2 2 2 0 KIAA1430 homologue YabA PF06156.13 KKK24972.1 - 3.2 8.4 9.6 15 6.3 0.4 2.6 1 1 1 2 2 2 0 Initiation control protein YabA Cep57_CLD_2 PF14197.6 KKK24972.1 - 4 7.6 9.8 18 5.5 0.5 2.7 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 Asp_protease PF09668.10 KKK24973.1 - 1.4e-61 205.7 0.1 2.2e-61 205.1 0.1 1.3 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 KKK24973.1 - 2.3e-22 79.4 0.0 6.8e-22 77.8 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease ubiquitin PF00240.23 KKK24973.1 - 1.8e-10 40.4 0.0 3.1e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Asp_protease_2 PF13650.6 KKK24973.1 - 2e-10 41.1 0.0 5.4e-10 39.8 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease UBA PF00627.31 KKK24973.1 - 2.2e-05 24.2 0.0 5.8e-05 22.9 0.0 1.8 1 0 0 1 1 1 1 UBA/TS-N domain Rad60-SLD PF11976.8 KKK24973.1 - 0.00055 19.7 0.0 0.0011 18.7 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like RVP_2 PF08284.11 KKK24973.1 - 0.0023 17.7 0.0 0.005 16.6 0.0 1.5 1 1 0 1 1 1 1 Retroviral aspartyl protease RVP PF00077.20 KKK24973.1 - 0.0051 17.1 0.0 0.016 15.5 0.0 1.9 1 0 0 1 1 1 1 Retroviral aspartyl protease Ubiquitin_4 PF18036.1 KKK24973.1 - 0.012 15.6 0.1 0.7 10.0 0.0 3.1 2 1 1 3 3 3 0 Ubiquitin-like domain UBA_4 PF14555.6 KKK24973.1 - 0.013 15.3 0.0 0.032 14.1 0.0 1.6 1 0 0 1 1 1 0 UBA-like domain NAD_binding_7 PF13241.6 KKK24973.1 - 0.042 14.3 0.1 0.83 10.1 0.0 2.3 2 0 0 2 2 2 0 Putative NAD(P)-binding UN_NPL4 PF11543.8 KKK24973.1 - 0.14 12.7 0.0 0.26 11.8 0.0 1.4 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Cys_Met_Meta_PP PF01053.20 KKK24974.1 - 8.2e-11 41.0 0.1 1e-10 40.7 0.1 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DUF2781 PF10914.8 KKK24975.1 - 2.4e-40 138.3 8.0 2.7e-40 138.1 8.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) Glyco_transf_90 PF05686.12 KKK24987.1 - 7.8e-18 64.6 0.2 9.9e-18 64.2 0.2 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 90 p450 PF00067.22 KKK24988.1 - 1.7e-49 168.9 0.0 3.9e-49 167.7 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 Phytochelatin_C PF09328.10 KKK24988.1 - 0.076 12.3 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1984) PMP1_2 PF08114.11 KKK25003.1 - 0.0069 16.1 0.3 0.013 15.2 0.3 1.5 1 0 0 1 1 1 1 ATPase proteolipid family DUF4381 PF14316.6 KKK25003.1 - 0.15 12.3 0.0 0.24 11.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) zf-LITAF-like PF10601.9 KKK25004.1 - 9e-21 73.9 7.5 1.1e-20 73.6 7.5 1.1 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain Zn-ribbon_8 PF09723.10 KKK25004.1 - 0.0063 16.6 0.5 0.07 13.3 0.2 2.2 2 0 0 2 2 2 1 Zinc ribbon domain TF_Zn_Ribbon PF08271.12 KKK25004.1 - 0.039 13.5 1.0 6.8 6.3 0.1 2.3 2 0 0 2 2 2 0 TFIIB zinc-binding Zn_ribbon_SprT PF17283.2 KKK25004.1 - 0.64 10.0 5.3 0.28 11.1 0.9 2.1 2 0 0 2 2 2 0 SprT-like zinc ribbon domain NAD_binding_11 PF14833.6 KKK25005.1 - 2.8e-39 134.1 2.6 1.8e-27 96.0 0.0 2.6 3 0 0 3 3 3 2 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase NAD_binding_2 PF03446.15 KKK25005.1 - 4.9e-38 130.8 0.2 8.9e-38 129.9 0.2 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 KKK25005.1 - 0.0013 18.7 0.1 0.0036 17.2 0.0 1.7 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.17 KKK25005.1 - 0.0034 17.9 0.0 0.015 15.8 0.0 2.2 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Atg14 PF10186.9 KKK25007.1 - 0.0013 17.9 1.3 0.0022 17.2 1.3 1.3 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 F-box_4 PF15966.5 KKK25007.1 - 0.0058 16.5 0.0 0.012 15.5 0.0 1.5 1 0 0 1 1 1 1 F-box F-box-like PF12937.7 KKK25007.1 - 0.0064 16.4 0.0 0.014 15.3 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KKK25007.1 - 0.058 13.3 0.1 0.13 12.1 0.1 1.6 1 0 0 1 1 1 0 F-box domain Oxidored-like PF09791.9 KKK25007.1 - 6.4 6.5 7.5 0.26 11.0 0.8 2.1 2 0 0 2 2 2 0 Oxidoreductase-like protein, N-terminal F_bP_aldolase PF01116.20 KKK25008.1 - 6.3e-58 196.5 0.6 4e-46 157.7 0.1 2.0 2 0 0 2 2 2 2 Fructose-bisphosphate aldolase class-II Methyltransf_24 PF13578.6 KKK25008.1 - 0.033 15.2 0.1 0.058 14.4 0.1 1.4 1 0 0 1 1 1 0 Methyltransferase domain DUF2007 PF09413.10 KKK25008.1 - 0.049 13.8 0.2 0.15 12.3 0.2 1.8 1 0 0 1 1 1 0 Putative prokaryotic signal transducing protein PTE PF02126.18 KKK25008.1 - 0.13 11.7 0.2 0.2 11.1 0.2 1.2 1 0 0 1 1 1 0 Phosphotriesterase family Fer2_3 PF13085.6 KKK25009.1 - 9.4e-32 109.3 0.0 1.5e-31 108.6 0.0 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.6 KKK25009.1 - 1e-08 35.6 5.8 1e-08 35.6 5.8 2.3 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 KKK25009.1 - 3.5e-07 30.2 3.0 3.5e-07 30.2 3.0 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 KKK25009.1 - 1.4e-06 28.7 13.0 1.8e-06 28.3 8.9 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer2 PF00111.27 KKK25009.1 - 0.0085 16.0 0.3 0.0085 16.0 0.3 2.2 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_7 PF12838.7 KKK25009.1 - 0.0099 16.5 5.9 0.0099 16.5 5.9 2.4 2 2 0 2 2 2 1 4Fe-4S dicluster domain Fer4_18 PF13746.6 KKK25009.1 - 0.13 12.5 5.4 0.4 10.9 0.1 2.9 3 1 0 3 3 3 0 4Fe-4S dicluster domain Fer4_9 PF13187.6 KKK25009.1 - 3.6 7.8 12.8 19 5.5 10.0 2.9 2 1 2 4 4 4 0 4Fe-4S dicluster domain Pec_lyase_C PF00544.19 KKK25010.1 - 1.5e-07 31.2 5.3 7.4e-07 29.0 5.3 2.1 1 1 0 1 1 1 1 Pectate lyase RRM_2 PF04059.12 KKK25067.1 - 2.8e-40 136.4 1.0 5.8e-40 135.4 0.6 1.8 2 0 0 2 2 2 1 RNA recognition motif 2 RRM_1 PF00076.22 KKK25067.1 - 1.1e-10 41.2 0.0 0.019 14.8 0.0 3.8 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TRAPP PF04051.16 KKK25068.1 - 5.3e-48 162.5 0.0 6.2e-48 162.2 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component PINIT PF14324.6 KKK25069.1 - 1.2e-40 139.2 0.1 2.6e-40 138.1 0.1 1.6 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.20 KKK25069.1 - 2.9e-22 78.1 6.7 5.4e-22 77.3 6.7 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger SAP PF02037.27 KKK25069.1 - 1.4e-07 31.1 2.9 2.2e-07 30.4 0.2 2.6 2 0 0 2 2 2 1 SAP domain zf-Nse PF11789.8 KKK25069.1 - 4.3e-07 29.6 2.1 1e-06 28.5 2.1 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-Sec23_Sec24 PF04810.15 KKK25069.1 - 0.15 12.1 0.8 0.38 10.9 0.6 1.8 1 1 0 1 1 1 0 Sec23/Sec24 zinc finger Prok-RING_4 PF14447.6 KKK25069.1 - 0.33 10.9 3.0 0.72 9.8 3.0 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 DUF2423 PF10338.9 KKK25070.1 - 4e-21 75.0 2.0 4e-21 75.0 2.0 2.1 3 0 0 3 3 3 1 Protein of unknown function (DUF2423) GAGE PF05831.11 KKK25070.1 - 0.19 12.3 5.0 0.072 13.6 2.8 1.6 1 1 1 2 2 2 0 GAGE protein Phosphodiest PF01663.22 KKK25071.1 - 7e-13 48.9 2.6 7.7e-09 35.6 0.4 2.2 1 1 1 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 KKK25071.1 - 8.9e-05 22.0 0.0 0.00031 20.2 0.0 1.8 2 0 0 2 2 2 1 Sulfatase Metalloenzyme PF01676.18 KKK25071.1 - 0.005 16.2 0.1 0.0084 15.5 0.1 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily DUF2207 PF09972.9 KKK25071.1 - 0.1 11.4 0.9 0.2 10.4 0.0 1.9 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) DUF229 PF02995.17 KKK25071.1 - 0.15 10.6 0.0 0.23 10.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Ldh_1_N PF00056.23 KKK25073.1 - 5.5e-46 156.2 0.0 9.8e-46 155.3 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 KKK25073.1 - 2.7e-43 147.8 0.0 3.7e-43 147.4 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.19 KKK25073.1 - 0.00029 19.9 0.0 0.00045 19.3 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KKK25073.1 - 0.0068 16.3 0.0 0.014 15.3 0.0 1.6 1 0 0 1 1 1 1 NAD(P)H-binding Glyco_hydro_4 PF02056.16 KKK25073.1 - 0.0074 15.9 0.0 0.13 11.9 0.0 2.2 1 1 1 2 2 2 1 Family 4 glycosyl hydrolase Semialdhyde_dh PF01118.24 KKK25073.1 - 0.024 15.1 0.0 0.048 14.1 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain CBFD_NFYB_HMF PF00808.23 KKK25074.1 - 9.5e-19 67.5 0.5 1.6e-18 66.7 0.5 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KKK25074.1 - 9.5e-16 58.4 0.1 1.5e-15 57.7 0.1 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.10 KKK25074.1 - 0.072 13.4 0.0 0.12 12.7 0.0 1.4 1 0 0 1 1 1 0 CENP-S associating Centromere protein X Sec15 PF04091.12 KKK25075.1 - 4.5e-107 358.1 0.4 4.5e-107 358.1 0.4 2.0 2 0 0 2 2 2 1 Exocyst complex subunit Sec15-like COG2 PF06148.11 KKK25075.1 - 0.0012 18.9 6.5 0.0012 18.9 6.5 2.9 3 1 0 3 3 3 1 COG (conserved oligomeric Golgi) complex component, COG2 Sec8_exocyst PF04048.14 KKK25075.1 - 0.0013 18.6 4.8 0.0013 18.6 4.8 2.3 2 0 0 2 2 2 1 Sec8 exocyst complex component specific domain Sec5 PF15469.6 KKK25075.1 - 0.0051 16.6 6.6 0.017 14.9 2.8 2.8 2 0 0 2 2 2 1 Exocyst complex component Sec5 COG5 PF10392.9 KKK25075.1 - 0.0077 16.4 7.1 0.016 15.4 5.1 2.5 2 0 0 2 2 2 1 Golgi transport complex subunit 5 Vps51 PF08700.11 KKK25075.1 - 0.077 13.1 3.7 0.14 12.3 1.1 2.7 2 0 0 2 2 2 0 Vps51/Vps67 Vps54_N PF10475.9 KKK25075.1 - 0.089 12.1 11.2 0.059 12.7 7.9 2.0 2 0 0 2 2 2 0 Vacuolar-sorting protein 54, of GARP complex FUSC PF04632.12 KKK25075.1 - 2.7 6.4 6.6 4 5.8 6.6 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF3510 PF12022.8 KKK25075.1 - 4.2 7.8 8.3 4.6 7.6 0.0 3.9 3 2 1 5 5 5 0 Domain of unknown function (DUF3510) PNP_UDP_1 PF01048.20 KKK25076.1 - 1e-49 168.9 0.1 1.4e-49 168.5 0.1 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily Fcf2 PF08698.11 KKK25077.1 - 6.8e-37 125.8 0.5 1.5e-36 124.7 0.1 1.7 1 1 1 2 2 2 2 Fcf2 pre-rRNA processing NAD_binding_8 PF13450.6 KKK25080.1 - 7.8e-14 51.7 0.0 1.9e-13 50.4 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 KKK25080.1 - 3.5e-05 23.3 0.1 0.0001 21.8 0.0 1.7 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase DAO PF01266.24 KKK25080.1 - 0.00011 21.9 0.1 0.063 12.8 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KKK25080.1 - 0.00014 21.2 0.1 0.49 9.6 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KKK25080.1 - 0.028 13.5 0.0 0.042 12.9 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.6 KKK25080.1 - 0.069 13.1 0.2 2 8.4 0.0 2.6 2 0 0 2 2 2 0 FAD-NAD(P)-binding HATPase_c_3 PF13589.6 KKK25081.1 - 3.3e-21 75.6 0.0 5.3e-21 74.9 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MutL_C PF08676.11 KKK25081.1 - 6e-09 35.8 0.0 3.2e-08 33.5 0.0 2.0 2 0 0 2 2 2 1 MutL C terminal dimerisation domain HATPase_c PF02518.26 KKK25081.1 - 0.0039 17.7 0.0 0.0098 16.4 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Lipoprotein_21 PF14041.6 KKK25081.1 - 0.11 12.7 0.0 0.3 11.2 0.0 1.7 1 0 0 1 1 1 0 LppP/LprE lipoprotein RasGEF PF00617.19 KKK25083.1 - 1.6e-50 171.8 0.3 3.5e-50 170.7 0.3 1.6 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 KKK25083.1 - 3e-15 56.4 0.0 9.1e-15 54.8 0.0 1.8 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_9 PF14604.6 KKK25083.1 - 1.3e-06 28.2 0.1 4.2e-06 26.5 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 KKK25083.1 - 1.2e-05 24.9 0.0 3.2e-05 23.4 0.0 1.8 1 0 0 1 1 1 1 SH3 domain CwfJ_C_1 PF04677.15 KKK25085.1 - 2.6e-30 104.8 0.0 4.7e-29 100.7 0.0 2.2 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.14 KKK25085.1 - 6.8e-27 94.2 0.0 6.8e-27 94.2 0.0 2.4 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 2 DUF3010 PF11215.8 KKK25085.1 - 0.25 11.6 1.5 11 6.3 0.3 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3010) ATP_bind_1 PF03029.17 KKK25086.1 - 1.3e-70 237.9 0.0 2.2e-70 237.2 0.0 1.3 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.27 KKK25086.1 - 7e-05 22.4 0.0 0.0016 18.0 0.0 2.9 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain MeaB PF03308.16 KKK25086.1 - 0.0011 18.0 0.0 0.026 13.5 0.0 2.3 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Methyltransf_32 PF13679.6 KKK25086.1 - 0.014 15.4 0.4 0.035 14.1 0.4 1.7 1 1 0 1 1 1 0 Methyltransferase domain CobT PF06213.12 KKK25086.1 - 0.015 14.7 10.9 0.022 14.2 10.9 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT FeoB_N PF02421.18 KKK25086.1 - 0.038 13.5 0.0 0.13 11.8 0.0 1.9 2 0 0 2 2 2 0 Ferrous iron transport protein B IlvC PF01450.19 KKK25086.1 - 0.063 13.6 1.9 3.2 8.0 0.0 2.2 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain PRK PF00485.18 KKK25086.1 - 0.063 13.0 0.0 0.18 11.5 0.0 1.7 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family NACHT PF05729.12 KKK25086.1 - 0.11 12.4 0.0 0.66 9.9 0.0 2.0 2 0 0 2 2 2 0 NACHT domain cobW PF02492.19 KKK25086.1 - 0.17 11.5 0.0 21 4.6 0.0 2.4 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Zn_clus PF00172.18 KKK25087.1 - 1.5e-08 34.6 8.6 2.3e-08 34.0 8.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain 2-Hacid_dh_C PF02826.19 KKK25088.1 - 4.8e-57 192.2 0.0 6.7e-57 191.7 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KKK25088.1 - 6.5e-14 51.7 0.0 8e-14 51.4 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KKK25088.1 - 4.6e-05 23.6 0.1 7.5e-05 22.9 0.1 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 KKK25088.1 - 0.023 14.3 0.0 0.041 13.5 0.0 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain F420_oxidored PF03807.17 KKK25088.1 - 0.083 13.5 0.1 0.21 12.2 0.0 1.7 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Peptidase_S8 PF00082.22 KKK25089.1 - 2e-31 109.3 16.1 5.9e-31 107.8 16.1 1.6 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 KKK25089.1 - 4.7e-19 68.9 0.3 8.5e-19 68.0 0.3 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 TauE PF01925.19 KKK25090.1 - 0.27 10.8 7.2 0.023 14.3 2.3 1.6 2 0 0 2 2 2 0 Sulfite exporter TauE/SafE TSA PF03249.13 KKK25091.1 - 1.3 7.7 5.6 6.7 5.4 0.7 2.2 2 0 0 2 2 2 0 Type specific antigen GST_N_3 PF13417.6 KKK25092.1 - 3.4e-20 72.2 0.0 6.8e-20 71.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KKK25092.1 - 1.2e-17 63.9 0.0 2.7e-17 62.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KKK25092.1 - 2.2e-08 34.3 0.0 4.1e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KKK25092.1 - 4.9e-07 29.7 0.3 1.1e-06 28.5 0.3 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 KKK25092.1 - 7.2e-06 26.5 0.0 1.4e-05 25.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KKK25092.1 - 0.012 15.8 0.0 0.027 14.7 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 KKK25092.1 - 0.052 13.8 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 Glutaredoxin Cas_Cas02710 PF09670.10 KKK25092.1 - 0.073 11.9 0.0 0.11 11.2 0.0 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Cas02710) MFS_1 PF07690.16 KKK25093.1 - 3.3e-17 62.5 36.5 3e-16 59.3 30.0 2.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KKK25093.1 - 7.1e-11 41.6 7.7 7.1e-11 41.6 7.7 1.9 2 0 0 2 2 2 1 Sugar (and other) transporter SUZ PF12752.7 KKK25095.1 - 3.8e-05 24.4 5.7 3.8e-05 24.4 5.7 3.4 2 1 1 3 3 3 1 SUZ domain DEAD PF00270.29 KKK25105.1 - 2.1e-37 128.6 0.0 3.8e-37 127.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KKK25105.1 - 2.2e-25 89.2 0.0 8e-24 84.1 0.1 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KKK25105.1 - 1.8e-07 31.3 0.0 3.7e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 KKK25105.1 - 0.013 14.9 0.1 0.056 12.8 0.0 1.9 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit Wbp11 PF09429.10 KKK25106.1 - 4.8e-20 71.7 13.4 4.8e-20 71.7 13.4 2.6 3 1 0 3 3 3 1 WW domain binding protein 11 DUF3038 PF11237.8 KKK25106.1 - 0.0085 16.1 1.8 0.014 15.4 1.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3038) FUSC PF04632.12 KKK25106.1 - 1.3 7.5 2.3 2.4 6.6 2.3 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family T3SSipB PF16535.5 KKK25107.1 - 0.015 15.8 0.3 0.03 14.8 0.3 1.5 1 0 0 1 1 1 0 Type III cell invasion protein SipB DUF1664 PF07889.12 KKK25107.1 - 0.034 14.2 1.9 0.2 11.7 1.9 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.10 KKK25107.1 - 0.038 14.2 2.9 0.1 12.8 2.9 1.6 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Pox_A_type_inc PF04508.12 KKK25107.1 - 0.041 13.7 3.5 0.47 10.4 0.1 3.2 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat Fzo_mitofusin PF04799.13 KKK25107.1 - 0.043 13.4 0.7 0.086 12.4 0.7 1.5 1 1 0 1 1 1 0 fzo-like conserved region Baculo_PEP_C PF04513.12 KKK25107.1 - 0.045 13.8 2.5 1.5 8.8 1.3 2.1 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.12 KKK25107.1 - 0.067 13.7 2.2 3 8.4 2.2 2.5 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein HSCB_C PF07743.13 KKK25107.1 - 0.11 13.0 2.9 1.1 9.8 0.5 2.3 1 1 1 2 2 2 0 HSCB C-terminal oligomerisation domain DUF1640 PF07798.11 KKK25107.1 - 0.12 12.4 3.4 0.47 10.5 3.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1640) Nbl1_Borealin_N PF10444.9 KKK25107.1 - 0.16 11.6 5.1 0.28 10.8 1.1 2.5 2 0 0 2 2 2 0 Nbl1 / Borealin N terminal NAP PF00956.18 KKK25107.1 - 0.18 10.9 0.2 0.22 10.7 0.2 1.1 1 0 0 1 1 1 0 Nucleosome assembly protein (NAP) Utp12 PF04003.12 KKK25107.1 - 0.77 10.1 3.3 0.76 10.1 1.8 1.9 2 1 0 2 2 2 0 Dip2/Utp12 Family Rpr2 PF04032.16 KKK25108.1 - 1.2e-25 89.6 0.5 1.2e-25 89.6 0.5 1.8 2 0 0 2 2 2 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain DZR PF12773.7 KKK25108.1 - 0.18 11.9 3.0 0.68 10.0 3.0 2.1 1 1 0 1 1 1 0 Double zinc ribbon DUF2897 PF11446.8 KKK25108.1 - 0.94 9.4 3.8 1.7 8.6 3.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) Pkinase PF00069.25 KKK25109.1 - 5.5e-54 183.3 5.5 4.5e-34 118.0 0.0 2.9 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 KKK25109.1 - 2.6e-36 125.3 0.0 4.9e-25 88.3 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 KKK25109.1 - 0.0052 15.6 4.4 0.11 11.2 0.0 2.3 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 KKK25109.1 - 0.01 15.2 1.1 0.02 14.3 0.0 1.9 2 0 0 2 2 2 0 Kinase-like APH PF01636.23 KKK25109.1 - 0.043 13.7 1.9 0.24 11.3 0.0 2.6 2 1 1 3 3 3 0 Phosphotransferase enzyme family DUF99 PF01949.16 KKK25109.1 - 0.17 11.3 1.0 0.32 10.4 1.0 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF99 DUF677 PF05055.12 KKK25109.1 - 0.18 10.6 8.5 0.28 10.0 8.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF677) DUF3896 PF13035.6 KKK25109.1 - 0.2 11.8 6.6 0.57 10.4 0.6 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3896) Colicin PF01024.19 KKK25109.1 - 0.45 10.4 1.7 0.79 9.6 1.7 1.3 1 0 0 1 1 1 0 Colicin pore forming domain ALMT PF11744.8 KKK25109.1 - 7.8 5.2 6.2 12 4.6 6.2 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter V_ATPase_I PF01496.19 KKK25109.1 - 8.6 4.1 6.1 12 3.6 6.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family BTB PF00651.31 KKK25110.1 - 2.8e-25 88.7 0.0 3.1e-14 53.1 0.1 2.6 2 0 0 2 2 2 2 BTB/POZ domain Glyco_hydro_35 PF01301.19 KKK25120.1 - 5.2e-74 249.7 6.5 7.8e-74 249.1 6.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.6 KKK25120.1 - 1.4e-58 196.4 0.6 3.7e-32 111.3 0.0 2.6 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain BetaGal_dom2 PF10435.9 KKK25120.1 - 3.7e-54 183.3 3.2 3.7e-54 183.3 3.2 1.9 2 0 0 2 2 2 1 Beta-galactosidase, domain 2 Y_phosphatase3 PF13350.6 KKK25120.1 - 9.1e-28 97.8 0.1 2.7e-27 96.3 0.0 1.8 2 0 0 2 2 2 1 Tyrosine phosphatase family BetaGal_dom3 PF13363.6 KKK25120.1 - 3.7e-24 84.1 0.2 1.6e-23 82.1 0.1 2.1 2 0 0 2 2 2 1 Beta-galactosidase, domain 3 Cellulase PF00150.18 KKK25120.1 - 9.1e-05 22.0 1.4 0.16 11.4 0.0 2.6 2 1 1 3 3 3 2 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_42 PF02449.15 KKK25120.1 - 9.5e-05 21.9 0.1 0.0011 18.4 0.2 2.2 1 1 1 2 2 2 1 Beta-galactosidase Y_phosphatase2 PF03162.13 KKK25120.1 - 0.0066 16.0 0.0 0.023 14.3 0.0 1.8 2 0 0 2 2 2 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 KKK25120.1 - 0.012 15.2 0.0 0.023 14.3 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase DSPc PF00782.20 KKK25120.1 - 0.096 12.5 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Eisosome1 PF12757.7 KKK25121.1 - 1.7e-29 102.6 9.8 1.7e-29 102.6 9.8 3.3 5 0 0 5 5 5 1 Eisosome protein 1 Pkinase PF00069.25 KKK25123.1 - 1.2e-66 224.8 0.0 1.8e-66 224.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK25123.1 - 1e-41 143.0 0.0 1.5e-41 142.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KKK25123.1 - 8.6e-09 35.1 0.0 3.2e-08 33.2 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 KKK25123.1 - 1.6e-06 27.4 0.3 1.6e-06 27.4 0.3 1.8 2 0 0 2 2 2 1 Haspin like kinase domain TMIE PF16038.5 KKK25123.1 - 0.057 13.3 0.1 0.057 13.3 0.1 2.0 2 0 0 2 2 2 0 TMIE protein Kdo PF06293.14 KKK25123.1 - 0.087 12.2 0.1 0.26 10.6 0.1 1.7 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ferlin_C PF16165.5 KKK25123.1 - 0.21 11.5 0.5 0.41 10.6 0.5 1.4 1 0 0 1 1 1 0 Ferlin C-terminus APH PF01636.23 KKK25123.1 - 0.44 10.4 4.4 1.2 9.0 0.1 2.8 2 1 1 3 3 3 0 Phosphotransferase enzyme family PRKG1_interact PF15898.5 KKK25123.1 - 0.82 10.6 10.4 0.056 14.4 4.4 2.2 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain Rtt106 PF08512.12 KKK25124.1 - 4.6e-31 107.1 0.1 1.2e-30 105.7 0.1 1.8 2 0 0 2 2 1 1 Histone chaperone Rttp106-like Pkinase PF00069.25 KKK25124.1 - 1.1e-26 93.8 0.0 1.7e-26 93.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK25124.1 - 9.7e-14 51.3 0.0 1.4e-13 50.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KKK25124.1 - 2.1e-07 30.1 0.2 3.7e-07 29.3 0.2 1.4 1 1 0 1 1 1 1 Fungal protein kinase Mpp10 PF04006.12 KKK25124.1 - 0.04 12.4 15.4 0.057 11.9 15.4 1.1 1 0 0 1 1 1 0 Mpp10 protein ZapC PF07126.12 KKK25124.1 - 0.059 13.0 1.2 2.5 7.7 0.3 2.3 2 0 0 2 2 2 0 Cell-division protein ZapC PH_18 PF18469.1 KKK25124.1 - 0.12 12.4 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain CDC45 PF02724.14 KKK25124.1 - 0.45 8.7 11.0 0.63 8.3 11.0 1.1 1 0 0 1 1 1 0 CDC45-like protein COPI_C PF06957.11 KKK25124.1 - 0.46 9.2 2.8 0.78 8.4 2.8 1.4 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus Nop14 PF04147.12 KKK25124.1 - 0.49 8.6 22.3 0.76 7.9 22.3 1.2 1 0 0 1 1 1 0 Nop14-like family Vfa1 PF08432.10 KKK25124.1 - 0.49 10.7 8.4 1.1 9.5 8.4 1.6 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 SDA1 PF05285.12 KKK25124.1 - 3.6 6.9 23.0 6.3 6.1 23.0 1.3 1 0 0 1 1 1 0 SDA1 Paf1 PF03985.13 KKK25124.1 - 5.9 5.8 12.9 9.1 5.2 12.9 1.2 1 0 0 1 1 1 0 Paf1 Prenyltrans PF00432.21 KKK25125.1 - 9e-33 111.7 9.9 2.1e-10 40.1 0.1 6.5 6 1 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_C PF13243.6 KKK25125.1 - 0.02 14.0 0.0 0.61 9.1 0.0 2.9 2 1 0 2 2 2 0 Squalene-hopene cyclase C-terminal domain DnaJ PF00226.31 KKK25126.1 - 2.3e-09 37.3 0.8 2.2e-08 34.1 0.2 2.2 2 0 0 2 2 2 1 DnaJ domain Frag1 PF10277.9 KKK25127.1 - 2e-45 155.0 16.5 2.3e-45 154.8 16.5 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family DUF645 PF04875.12 KKK25127.1 - 0.043 13.8 1.4 4.8 7.3 0.2 2.8 1 1 1 2 2 2 0 Protein of unknown function, DUF645 PRA1 PF03208.19 KKK25128.1 - 4.3e-38 130.1 0.8 5.1e-38 129.9 0.8 1.0 1 0 0 1 1 1 1 PRA1 family protein TraS PF10624.9 KKK25128.1 - 0.11 12.4 2.0 0.68 9.8 0.3 2.1 2 0 0 2 2 2 0 Plasmid conjugative transfer entry exclusion protein TraS DUF2207 PF09972.9 KKK25128.1 - 0.23 10.2 1.6 0.29 9.9 1.6 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) CFEM PF05730.11 KKK25130.1 - 4e-14 52.5 15.3 4e-14 52.5 15.3 2.3 2 1 0 2 2 2 1 CFEM domain Tmemb_cc2 PF10267.9 KKK25130.1 - 0.14 11.3 5.0 0.15 11.2 5.0 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein SOG2 PF10428.9 KKK25130.1 - 0.98 8.5 13.8 1.2 8.3 13.8 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Macoilin PF09726.9 KKK25130.1 - 1.6 7.2 8.6 1.8 7.0 8.6 1.1 1 0 0 1 1 1 0 Macoilin family Mog1 PF04603.12 KKK25130.1 - 1.8 8.9 5.1 3.4 8.0 5.1 1.5 1 1 0 1 1 1 0 Ran-interacting Mog1 protein GREB1 PF15782.5 KKK25130.1 - 2.2 5.3 6.1 2.3 5.3 6.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF515 PF04415.12 KKK25130.1 - 3 6.2 15.8 3.4 5.9 15.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF515) TIL PF01826.17 KKK25130.1 - 5.1 7.4 13.3 1.4 9.2 9.5 2.0 2 0 0 2 2 2 0 Trypsin Inhibitor like cysteine rich domain Ilm1 PF10311.9 KKK25131.1 - 1.2e-63 213.6 1.3 1.4e-63 213.4 1.3 1.0 1 0 0 1 1 1 1 Increased loss of mitochondrial DNA protein 1 MFS_1 PF07690.16 KKK25132.1 - 2.3e-34 118.9 18.4 2.3e-34 118.9 18.4 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KKK25132.1 - 2.4e-10 39.9 6.2 2.4e-10 39.9 6.2 3.0 2 1 1 3 3 3 1 Sugar (and other) transporter Phage_holin_3_1 PF05106.12 KKK25132.1 - 1.1 9.7 7.5 1.8 9.1 0.3 3.1 3 0 0 3 3 3 0 Phage holin family (Lysis protein S) NAD_kinase PF01513.21 KKK25169.1 - 2.2e-68 230.6 0.0 3.1e-68 230.1 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase DUF2848 PF11010.8 KKK25169.1 - 0.035 13.7 0.0 0.055 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2848) DUF1583 PF07622.11 KKK25169.1 - 0.063 12.0 0.0 0.093 11.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1583) TRAPP PF04051.16 KKK25170.1 - 5e-40 136.6 0.0 6.6e-40 136.2 0.0 1.2 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component GTP_EFTU PF00009.27 KKK25179.1 - 0.0013 18.4 0.0 0.0013 18.3 0.0 1.0 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain NAD_binding_2 PF03446.15 KKK25188.1 - 4.2e-34 118.0 0.1 6.4e-34 117.4 0.1 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 KKK25188.1 - 3.9e-30 104.6 0.0 7e-30 103.8 0.0 1.5 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 KKK25188.1 - 5e-06 27.0 0.0 1.2e-05 25.8 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent OCD_Mu_crystall PF02423.15 KKK25188.1 - 0.00063 18.8 0.0 0.0012 17.8 0.0 1.4 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family UDPG_MGDP_dh PF00984.19 KKK25188.1 - 0.026 14.7 0.2 0.14 12.4 0.1 2.2 2 1 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, central domain TGS PF02824.21 KKK25188.1 - 0.091 12.8 0.1 0.41 10.7 0.0 2.1 2 0 0 2 2 2 0 TGS domain MOR2-PAG1_N PF14222.6 KKK25189.1 - 5.1e-212 705.7 0.0 8e-212 705.1 0.0 1.3 1 0 0 1 1 1 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.6 KKK25189.1 - 3.6e-90 302.2 0.0 1.1e-89 300.7 0.0 1.9 2 0 0 2 2 2 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.6 KKK25189.1 - 9.1e-36 123.0 12.3 1.1e-13 49.9 0.0 4.0 2 1 1 3 3 3 3 Cell morphogenesis central region MARVEL PF01284.23 KKK25190.1 - 0.011 15.8 18.1 0.034 14.2 18.5 1.6 1 1 0 1 1 1 0 Membrane-associating domain Saf_2TM PF18303.1 KKK25190.1 - 0.055 13.1 0.2 0.11 12.1 0.1 1.6 1 1 0 1 1 1 0 SAVED-fused 2TM effector domain DUF2207 PF09972.9 KKK25190.1 - 0.93 8.2 7.2 2.2 7.0 0.0 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Glyco_hydro_61 PF03443.14 KKK25191.1 - 0.0048 16.9 0.0 0.011 15.6 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 61 SPX PF03105.19 KKK25191.1 - 0.17 11.8 3.8 0.17 11.7 3.8 1.1 1 0 0 1 1 1 0 SPX domain SOG2 PF10428.9 KKK25191.1 - 3.9 6.6 14.8 4.9 6.2 14.8 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Sporozoite_P67 PF05642.11 KKK25191.1 - 7.7 4.5 15.4 9.4 4.2 15.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen UvdE PF03851.14 KKK25192.1 - 7.9e-111 369.7 0.0 1e-110 369.4 0.0 1.1 1 0 0 1 1 1 1 UV-endonuclease UvdE BCMA-Tall_bind PF09257.10 KKK25192.1 - 0.057 13.5 1.1 0.15 12.1 1.1 1.7 1 0 0 1 1 1 0 BCMA, TALL-1 binding DUF2183 PF09949.9 KKK25193.1 - 1.2e-31 108.9 0.0 3e-31 107.7 0.0 1.7 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) CarboxypepD_reg PF13620.6 KKK25193.1 - 0.025 14.8 0.0 0.084 13.2 0.0 1.9 2 0 0 2 2 2 0 Carboxypeptidase regulatory-like domain FAD_binding_1 PF00667.20 KKK25194.1 - 3.2e-64 216.5 0.0 4.8e-64 216.0 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 KKK25194.1 - 1.5e-34 119.2 2.3 2.9e-34 118.3 2.3 1.5 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 KKK25194.1 - 4.3e-20 72.4 0.0 3.2e-19 69.6 0.0 2.2 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 KKK25194.1 - 0.11 12.7 0.0 0.33 11.2 0.0 1.8 1 0 0 1 1 1 0 Flavodoxin domain MMS1_N PF10433.9 KKK25195.1 - 1e-132 443.3 0.0 1.3e-132 442.9 0.0 1.1 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 KKK25195.1 - 8.5e-77 258.6 0.0 8.6e-74 248.7 0.0 3.7 4 0 0 4 4 4 2 CPSF A subunit region PGA2 PF07543.12 KKK25196.1 - 1.9e-49 167.2 4.0 2.3e-49 166.9 4.0 1.1 1 0 0 1 1 1 1 Protein trafficking PGA2 EST1 PF10374.9 KKK25196.1 - 0.019 15.6 1.2 0.066 13.8 1.1 1.9 1 1 1 2 2 2 0 Telomerase activating protein Est1 SelK_SelG PF10961.8 KKK25196.1 - 0.32 11.6 1.5 5.7 7.6 0.9 2.4 1 1 1 2 2 2 0 Selenoprotein SelK_SelG Topoisom_I_N PF02919.15 KKK25196.1 - 0.75 9.3 5.6 0.28 10.7 0.7 2.0 2 0 0 2 2 2 0 Eukaryotic DNA topoisomerase I, DNA binding fragment AP3D1 PF06375.11 KKK25196.1 - 2.5 8.3 11.1 0.22 11.7 1.2 2.1 1 1 1 2 2 2 0 AP-3 complex subunit delta-1 MAS20 PF02064.15 KKK25196.1 - 8.7 6.4 8.2 5.8 7.0 1.8 2.3 2 0 0 2 2 2 0 MAS20 protein import receptor CENP-S PF15630.6 KKK25197.1 - 3.2e-34 117.2 0.0 3.9e-34 116.9 0.0 1.1 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 KKK25197.1 - 4.9e-09 36.3 0.0 5.5e-09 36.1 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Bromo_TP PF07524.13 KKK25197.1 - 0.023 14.7 0.0 0.032 14.2 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated HAUS2 PF15003.6 KKK25197.1 - 0.026 14.3 0.1 0.028 14.1 0.1 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 2 CPSase_L_D2 PF02786.17 KKK25198.1 - 4.8e-114 379.1 0.2 5.2e-84 281.0 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.22 KKK25198.1 - 7.7e-48 161.6 0.0 1.9e-47 160.3 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain OTCace_N PF02729.21 KKK25198.1 - 6.3e-46 156.1 0.0 1.3e-45 155.1 0.0 1.6 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain GATase PF00117.28 KKK25198.1 - 1.7e-45 155.2 0.0 1.2e-44 152.4 0.0 2.2 2 0 0 2 2 2 1 Glutamine amidotransferase class-I CPSase_L_D3 PF02787.19 KKK25198.1 - 5.2e-38 130.1 0.0 1.2e-37 128.9 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain OTCace PF00185.24 KKK25198.1 - 2.2e-32 112.3 0.0 4.8e-32 111.2 0.0 1.6 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain MGS PF02142.22 KKK25198.1 - 2.9e-21 75.4 0.0 1.6e-20 73.1 0.0 2.4 2 0 0 2 2 2 1 MGS-like domain Dala_Dala_lig_C PF07478.13 KKK25198.1 - 1.8e-18 66.8 0.5 3.2e-08 33.3 0.1 2.4 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 KKK25198.1 - 3.8e-16 59.1 0.1 1.1e-07 31.6 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.6 KKK25198.1 - 4.1e-10 39.5 0.1 0.00012 21.9 0.0 2.9 3 0 0 3 3 3 2 ATP-grasp in the biosynthetic pathway with Ter operon Peptidase_C26 PF07722.13 KKK25198.1 - 7e-06 26.0 0.2 0.00055 19.7 0.2 2.7 1 1 0 1 1 1 1 Peptidase C26 ATP-grasp_3 PF02655.14 KKK25198.1 - 2.5e-05 24.4 0.7 0.2 11.7 0.1 2.9 3 0 0 3 3 3 2 ATP-grasp domain DJ-1_PfpI PF01965.24 KKK25198.1 - 7e-05 22.7 0.7 0.28 11.0 0.0 4.8 5 0 0 5 5 5 1 DJ-1/PfpI family GARS_A PF01071.19 KKK25198.1 - 0.001 18.9 0.3 0.41 10.4 0.0 2.8 3 0 0 3 3 3 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Peptidase_C25_C PF03785.14 KKK25198.1 - 0.039 13.8 0.6 0.75 9.7 0.2 3.1 2 0 0 2 2 2 0 Peptidase family C25, C terminal ig-like domain TrkA_N PF02254.18 KKK25198.1 - 0.17 12.2 0.1 1.5 9.1 0.0 2.6 2 0 0 2 2 2 0 TrkA-N domain Synaptobrevin PF00957.21 KKK25199.1 - 1.5e-31 108.0 0.0 2.1e-31 107.6 0.0 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 KKK25199.1 - 5.4e-28 96.9 0.1 8.4e-28 96.2 0.1 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain zf-C2H2_aberr PF17017.5 KKK25200.1 - 0.031 14.4 0.6 0.048 13.8 0.6 1.2 1 0 0 1 1 1 0 Aberrant zinc-finger FOXP-CC PF16159.5 KKK25200.1 - 0.45 11.2 3.9 4 8.1 0.4 2.7 1 1 1 2 2 2 0 FOXP coiled-coil domain Pkinase PF00069.25 KKK25201.1 - 9.6e-24 84.2 0.0 1.5e-23 83.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain HEAT PF02985.22 KKK25201.1 - 4.5e-10 38.9 11.6 0.027 14.7 0.1 6.8 7 0 0 7 7 7 3 HEAT repeat WD40 PF00400.32 KKK25201.1 - 5.4e-08 33.4 14.2 6.4e-06 26.8 0.1 5.2 5 0 0 5 5 5 2 WD domain, G-beta repeat HEAT_2 PF13646.6 KKK25201.1 - 3.7e-06 27.2 1.2 1.5 9.3 0.0 4.7 4 1 1 5 5 5 2 HEAT repeats Pkinase_Tyr PF07714.17 KKK25201.1 - 7.8e-05 22.1 0.0 0.00013 21.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT_EZ PF13513.6 KKK25201.1 - 0.00012 22.5 0.7 0.13 12.9 0.1 4.5 4 0 0 4 4 4 1 HEAT-like repeat Tti2 PF10521.9 KKK25201.1 - 0.00069 19.2 0.0 0.0014 18.2 0.0 1.4 1 0 0 1 1 1 1 Tti2 family Cnd1 PF12717.7 KKK25201.1 - 0.015 15.4 0.4 0.31 11.1 0.0 2.9 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 M11L PF11099.8 KKK25201.1 - 0.021 15.1 0.1 1.5 9.1 0.0 2.4 2 0 0 2 2 2 0 Apoptosis regulator M11L like RTP1_C1 PF10363.9 KKK25201.1 - 0.051 13.8 0.2 5.9 7.1 0.0 2.5 2 0 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 Ge1_WD40 PF16529.5 KKK25201.1 - 0.084 11.8 0.1 0.95 8.4 0.0 2.3 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Adaptin_N PF01602.20 KKK25201.1 - 0.12 10.9 1.6 2.2 6.7 0.2 2.2 2 0 0 2 2 2 0 Adaptin N terminal region adh_short_C2 PF13561.6 KKK25204.1 - 2e-53 181.3 2.1 2.4e-53 181.1 2.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KKK25204.1 - 8.2e-46 155.9 0.6 1e-45 155.6 0.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KKK25204.1 - 5.7e-11 42.7 0.2 1.3e-10 41.5 0.2 1.6 1 1 0 1 1 1 1 KR domain DUF3087 PF11286.8 KKK25204.1 - 0.02 14.4 0.0 2.4 7.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3087) DENN PF02141.21 KKK25205.1 - 3.2e-40 138.1 0.1 5.2e-40 137.4 0.1 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 KKK25205.1 - 0.00012 22.7 0.3 0.00076 20.2 0.1 2.5 2 0 0 2 2 2 1 uDENN domain Cnn_1N PF07989.11 KKK25205.1 - 2 8.6 16.4 0.11 12.7 3.3 3.1 3 1 0 3 3 3 0 Centrosomin N-terminal motif 1 DUF3450 PF11932.8 KKK25205.1 - 6.6 6.0 17.8 0.39 10.0 4.2 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) FlaC_arch PF05377.11 KKK25205.1 - 9.8 6.7 8.7 34 4.9 0.5 3.6 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Zn_clus PF00172.18 KKK25206.1 - 1.1e-09 38.3 4.0 1.9e-09 37.5 4.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KKK25206.1 - 9.6e-09 34.6 0.0 1.8e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain RabGAP-TBC PF00566.18 KKK25208.1 - 8.4e-42 143.3 0.0 7.7e-40 136.8 0.0 2.9 3 0 0 3 3 3 1 Rab-GTPase-TBC domain CNDH2_C PF16858.5 KKK25208.1 - 0.23 11.3 1.7 0.35 10.7 0.3 1.9 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term RNA_pol_3_Rpc31 PF11705.8 KKK25208.1 - 0.31 11.3 8.5 0.27 11.5 5.5 2.2 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 CENP-B_dimeris PF09026.10 KKK25208.1 - 0.74 10.2 17.0 2.2 8.7 17.0 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain LRS4 PF10422.9 KKK25208.1 - 0.76 9.3 9.7 0.58 9.7 1.6 2.9 2 0 0 2 2 2 0 Monopolin complex subunit LRS4 NOA36 PF06524.12 KKK25208.1 - 0.81 9.0 12.0 2 7.7 12.0 1.6 1 0 0 1 1 1 0 NOA36 protein RXT2_N PF08595.11 KKK25208.1 - 0.98 9.4 5.7 3.6 7.6 5.7 2.0 1 0 0 1 1 1 0 RXT2-like, N-terminal GEN1_C PF18380.1 KKK25208.1 - 1.5 9.8 4.3 1e+02 3.9 0.0 3.0 2 0 0 2 2 2 0 Holliday junction resolvase Gen1 C-terminal domain PBP1_TM PF14812.6 KKK25208.1 - 1.6 9.1 13.6 1.6 9.2 10.3 2.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DNA_pol_phi PF04931.13 KKK25208.1 - 3 5.8 11.3 4.7 5.2 11.3 1.2 1 0 0 1 1 1 0 DNA polymerase phi AMP-binding PF00501.28 KKK25209.1 - 4.4e-211 700.9 0.0 8.4e-74 248.7 0.0 3.3 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.20 KKK25209.1 - 5.7e-147 490.1 0.0 1.4e-38 132.8 0.0 5.7 5 1 1 6 6 6 5 Condensation domain PP-binding PF00550.25 KKK25209.1 - 3.7e-46 155.3 4.4 6.2e-12 45.7 0.0 5.8 5 0 0 5 5 5 5 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KKK25209.1 - 1.4e-13 51.6 0.8 5.9e-07 30.4 0.3 4.1 3 0 0 3 3 3 3 AMP-binding enzyme C-terminal domain Transferase PF02458.15 KKK25209.1 - 0.00035 19.3 0.0 0.85 8.2 0.0 3.9 4 0 0 4 4 4 2 Transferase family NUDIX PF00293.28 KKK25212.1 - 2.7e-25 88.9 0.0 4.2e-25 88.3 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain zf-C2H2_4 PF13894.6 KKK25213.1 - 3.7e-10 39.7 11.1 0.00049 20.7 0.2 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.26 KKK25213.1 - 4.5e-10 39.4 14.1 0.00071 19.9 0.1 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-met PF12874.7 KKK25213.1 - 2e-05 24.8 0.3 0.17 12.3 0.3 2.8 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 KKK25213.1 - 0.0038 17.6 10.8 0.2 12.1 0.3 3.3 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_6 PF13912.6 KKK25213.1 - 0.034 14.1 10.6 0.31 11.1 0.3 4.1 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2_2 PF12756.7 KKK25213.1 - 0.11 12.9 3.8 0.44 10.9 0.7 2.6 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 KKK25213.1 - 0.16 12.3 2.6 0.49 10.7 0.0 2.6 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-BED PF02892.15 KKK25213.1 - 1.1 9.3 6.7 12 6.1 0.0 3.1 2 1 1 3 3 3 0 BED zinc finger zf-C2H2_11 PF16622.5 KKK25213.1 - 2.9 7.7 7.7 24 4.8 0.3 3.3 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-C2H2_3rep PF18868.1 KKK25213.1 - 3.9 8.2 6.5 12 6.6 0.8 2.7 1 1 2 3 3 3 0 Zinc finger C2H2-type, 3 repeats zf_UBZ PF18439.1 KKK25213.1 - 9.8 5.9 6.2 36 4.0 0.2 3.2 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger MatE PF01554.18 KKK25214.1 - 2.1e-59 199.8 23.9 1.1e-35 122.7 7.5 2.5 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 KKK25214.1 - 0.0019 18.2 8.8 0.0019 18.2 8.8 3.9 3 1 0 4 4 4 2 Polysaccharide biosynthesis C-terminal domain DUF202 PF02656.15 KKK25215.1 - 5.7e-18 65.1 4.5 5.8e-18 65.1 0.4 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Tetraspanin PF00335.20 KKK25215.1 - 0.031 14.0 1.6 0.11 12.2 1.3 1.7 2 0 0 2 2 2 0 Tetraspanin family DUF716 PF04819.12 KKK25215.1 - 0.064 12.9 1.4 0.086 12.5 1.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF716) GWT1 PF06423.12 KKK25215.1 - 0.098 12.8 0.4 0.15 12.2 0.4 1.3 1 1 0 1 1 1 0 GWT1 DUF2976 PF11190.8 KKK25215.1 - 0.12 12.2 2.4 0.16 11.8 0.9 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2976) Yip1 PF04893.17 KKK25215.1 - 0.27 10.9 5.8 0.22 11.2 3.6 1.8 1 1 1 2 2 2 0 Yip1 domain DEAD PF00270.29 KKK25216.1 - 1.5e-48 164.8 0.3 1.1e-47 162.1 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KKK25216.1 - 4.8e-24 84.8 0.2 1.5e-22 80.0 0.2 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DBP10CT PF08147.12 KKK25216.1 - 7.1e-21 74.2 0.7 7.1e-21 74.2 0.7 2.5 2 0 0 2 2 2 1 DBP10CT (NUC160) domain RPA_C PF08784.11 KKK25217.1 - 2.4e-16 60.3 0.0 8.1e-16 58.6 0.0 1.9 2 0 0 2 2 2 1 Replication protein A C terminal tRNA_anti-codon PF01336.25 KKK25217.1 - 0.022 14.8 0.1 0.069 13.1 0.0 1.8 2 1 0 2 2 2 0 OB-fold nucleic acid binding domain HTH_24 PF13412.6 KKK25217.1 - 0.03 13.9 0.0 0.061 12.9 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding DEAD PF00270.29 KKK25218.1 - 1.9e-47 161.3 0.1 5.7e-47 159.7 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KKK25218.1 - 3e-24 85.5 0.0 1.8e-23 83.0 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 KKK25218.1 - 4.3e-20 71.7 0.0 1.4e-19 70.1 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 KKK25218.1 - 6.1e-06 26.3 0.0 6.1e-06 26.3 0.0 3.0 3 1 1 4 4 4 1 Type III restriction enzyme, res subunit Ant_C PF05586.11 KKK25218.1 - 6.9 7.4 8.5 3.4 8.3 0.0 3.5 3 0 0 3 3 3 0 Anthrax receptor C-terminus region DUF4538 PF15061.6 KKK25219.1 - 2.1 8.1 6.7 1.3 8.8 3.8 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4538) RRM_1 PF00076.22 KKK25220.1 - 2.2e-22 78.7 0.1 1.2e-10 41.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PAPS_reduct PF01507.19 KKK25221.1 - 2.8e-26 92.6 0.0 3e-24 86.0 0.0 2.8 2 1 0 2 2 2 1 Phosphoadenosine phosphosulfate reductase family DnaJ PF00226.31 KKK25221.1 - 2.1e-13 50.2 1.9 3.6e-13 49.4 0.5 2.3 2 0 0 2 2 2 1 DnaJ domain CDC45 PF02724.14 KKK25221.1 - 1.4 7.1 8.1 1.9 6.7 8.1 1.1 1 0 0 1 1 1 0 CDC45-like protein TPR_1 PF00515.28 KKK25224.1 - 4.8e-06 26.2 0.0 0.00035 20.3 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 KKK25224.1 - 7.7e-06 25.5 0.0 0.003 17.2 0.0 3.0 3 0 0 3 3 3 1 TPR repeat TPR_19 PF14559.6 KKK25224.1 - 1.5e-05 25.4 0.0 5.7e-05 23.5 0.0 2.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 KKK25224.1 - 1.6e-05 25.3 2.3 0.0052 17.5 0.1 4.0 3 2 1 4 4 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KKK25224.1 - 4.5e-05 23.2 0.2 0.0022 18.0 0.0 3.7 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_17 PF13431.6 KKK25224.1 - 6.2e-05 23.1 0.1 0.00048 20.3 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 KKK25224.1 - 0.00046 20.2 0.0 0.014 15.6 0.0 3.2 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 KKK25224.1 - 0.0024 18.0 0.9 0.007 16.5 0.2 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 KKK25224.1 - 0.013 16.1 0.0 0.047 14.3 0.0 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_7 PF13176.6 KKK25224.1 - 0.015 15.3 0.0 1.3 9.2 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_20 PF14561.6 KKK25224.1 - 0.02 15.2 0.0 0.057 13.8 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_12 PF13424.6 KKK25224.1 - 0.027 14.7 0.1 0.17 12.2 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TniQ PF06527.11 KKK25224.1 - 0.049 14.3 0.1 0.2 12.4 0.1 2.1 1 1 0 1 1 1 0 TniQ HrpJ PF07201.11 KKK25224.1 - 0.082 13.2 0.1 0.38 11.0 0.0 2.1 3 0 0 3 3 3 0 HrpJ-like domain Sigma70_r4 PF04545.16 KKK25224.1 - 0.34 10.5 4.3 7.4 6.2 2.4 2.5 2 0 0 2 2 2 0 Sigma-70, region 4 Adaptin_N PF01602.20 KKK25225.1 - 3.5e-50 171.0 0.0 8.8e-50 169.7 0.0 1.6 1 1 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.6 KKK25225.1 - 6.5e-05 23.2 2.5 0.29 11.5 0.1 3.5 3 0 0 3 3 3 2 HEAT repeats Cnd1 PF12717.7 KKK25225.1 - 8.4e-05 22.7 0.2 0.019 15.0 0.0 2.4 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KKK25225.1 - 0.014 15.6 1.4 9.3 6.8 0.1 3.9 3 0 0 3 3 3 0 HEAT repeat HEAT_EZ PF13513.6 KKK25225.1 - 0.026 15.0 3.6 32 5.2 0.0 4.9 6 0 0 6 6 6 0 HEAT-like repeat Cnd3 PF12719.7 KKK25225.1 - 0.04 13.1 0.1 1.2 8.3 0.0 2.5 2 0 0 2 2 2 0 Nuclear condensing complex subunits, C-term domain RAMP4 PF06624.12 KKK25226.1 - 3.4e-17 62.2 7.0 1e-16 60.7 7.0 1.6 1 1 0 1 1 1 1 Ribosome associated membrane protein RAMP4 APH PF01636.23 KKK25227.1 - 1.8e-12 47.7 0.0 4.3e-12 46.5 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KKK25227.1 - 0.00058 19.5 0.0 0.00079 19.1 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF1289 PF06945.13 KKK25227.1 - 0.21 11.4 0.3 0.72 9.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1289) Utp21 PF04192.12 KKK25228.1 - 2.1e-68 230.3 0.0 3.3e-68 229.7 0.0 1.2 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.32 KKK25228.1 - 6e-18 64.9 33.4 6.9e-05 23.5 0.4 10.9 11 0 0 11 11 11 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKK25228.1 - 4.2e-17 62.2 0.1 0.019 15.3 0.0 7.1 2 2 5 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain PALB2_WD40 PF16756.5 KKK25228.1 - 0.0012 17.8 0.2 0.025 13.5 0.0 2.5 3 0 0 3 3 3 1 Partner and localizer of BRCA2 WD40 domain Cytochrom_D1 PF02239.16 KKK25228.1 - 0.18 10.3 0.2 0.56 8.7 0.0 1.9 2 0 0 2 2 2 0 Cytochrome D1 heme domain XPG_I_2 PF12813.7 KKK25229.1 - 8.7e-77 258.0 0.0 1.2e-76 257.5 0.0 1.2 1 0 0 1 1 1 1 XPG domain containing Abhydrolase_6 PF12697.7 KKK25231.1 - 6.4e-09 36.7 2.4 9.5e-09 36.2 2.4 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KKK25231.1 - 2.7e-05 23.5 0.0 0.00012 21.4 0.0 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KKK25231.1 - 0.00012 21.8 0.0 0.00019 21.2 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 KKK25231.1 - 0.00014 21.8 0.0 0.00023 21.1 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KKK25231.1 - 0.054 13.0 0.0 3.1 7.2 0.0 2.3 2 0 0 2 2 2 0 Prolyl oligopeptidase family TFB6 PF17110.5 KKK25232.1 - 1.7 8.4 4.2 0.62 9.8 0.1 2.2 2 0 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH TLD PF07534.16 KKK25233.1 - 0.0011 19.2 0.0 0.0018 18.5 0.0 1.3 1 0 0 1 1 1 1 TLD DUF2368 PF10166.9 KKK25233.1 - 0.012 15.2 0.0 0.022 14.4 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2368) NMT_C PF02799.15 KKK25234.1 - 1.9e-87 292.2 0.0 3.3e-87 291.4 0.0 1.4 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.19 KKK25234.1 - 2.1e-74 248.7 0.6 2e-73 245.5 0.1 2.1 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_9 PF13527.7 KKK25234.1 - 6.4e-06 26.3 0.1 0.00016 21.8 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KKK25234.1 - 0.014 15.6 0.0 0.026 14.7 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family NTP_transf_9 PF04248.12 KKK25234.1 - 0.06 13.2 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF427) Mur_ligase_M PF08245.12 KKK25235.1 - 2.5e-06 27.6 1.2 0.0023 18.0 0.1 3.3 2 1 1 3 3 3 2 Mur ligase middle domain TANGO2 PF05742.12 KKK25236.1 - 1.1e-57 196.0 0.0 1.3e-57 195.7 0.0 1.0 1 0 0 1 1 1 1 Transport and Golgi organisation 2 Fungal_trans_2 PF11951.8 KKK25237.1 - 2.1e-07 30.1 0.0 5.2e-07 28.8 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK25237.1 - 2.5e-05 24.3 12.5 2.5e-05 24.3 12.5 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Lipase_2 PF01674.18 KKK25238.1 - 5.7e-08 32.5 0.1 1.5e-07 31.2 0.1 1.8 1 1 0 1 1 1 1 Lipase (class 2) Abhydrolase_1 PF00561.20 KKK25238.1 - 5.2e-06 26.3 0.3 2.1e-05 24.3 0.3 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KKK25238.1 - 1e-05 26.2 1.0 2.2e-05 25.2 1.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Palm_thioest PF02089.15 KKK25238.1 - 0.0047 16.8 0.0 0.014 15.3 0.0 1.7 1 1 0 1 1 1 1 Palmitoyl protein thioesterase DUF1749 PF08538.10 KKK25238.1 - 0.0075 15.4 0.0 0.011 14.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_2 PF02230.16 KKK25238.1 - 0.014 15.2 0.0 0.14 11.9 0.0 2.0 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase DUF900 PF05990.12 KKK25238.1 - 0.023 14.2 0.0 0.086 12.3 0.0 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) Hydrolase_4 PF12146.8 KKK25238.1 - 0.059 12.6 0.1 0.085 12.1 0.1 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 PGAP1 PF07819.13 KKK25238.1 - 0.064 13.0 1.0 0.18 11.5 0.0 2.0 2 1 0 3 3 3 0 PGAP1-like protein DUF676 PF05057.14 KKK25238.1 - 0.079 12.4 0.0 0.17 11.4 0.0 1.4 1 1 0 1 1 1 0 Putative serine esterase (DUF676) MFS_1 PF07690.16 KKK25239.1 - 7.1e-17 61.4 44.1 7.9e-10 38.2 9.5 3.3 3 1 1 4 4 4 2 Major Facilitator Superfamily Aldolase_II PF00596.21 KKK25240.1 - 7.9e-50 169.4 0.1 9.8e-50 169.1 0.1 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain GFA PF04828.14 KKK25241.1 - 5.4e-22 77.9 1.0 7.3e-22 77.5 1.0 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme LysM PF01476.20 KKK25242.1 - 4.4e-26 90.7 3.2 1.1e-09 38.1 0.0 4.4 4 0 0 4 4 4 4 LysM domain S-methyl_trans PF02574.16 KKK25243.1 - 5.7e-29 101.8 0.0 5.1e-16 59.3 0.0 2.0 1 1 1 2 2 2 2 Homocysteine S-methyltransferase UPF0113_N PF17833.1 KKK25245.1 - 1.9e-25 89.3 0.0 2.5e-25 88.8 0.0 1.2 1 0 0 1 1 1 1 UPF0113 Pre-PUA domain UPF0113 PF03657.13 KKK25245.1 - 2e-21 76.1 0.0 2.8e-21 75.5 0.0 1.2 1 0 0 1 1 1 1 UPF0113 PUA domain PUA PF01472.20 KKK25245.1 - 0.17 11.8 0.0 0.3 11.1 0.0 1.3 1 0 0 1 1 1 0 PUA domain Synaptobrevin PF00957.21 KKK25246.1 - 6.5e-14 51.5 0.1 9.8e-14 50.9 0.1 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 KKK25246.1 - 2.4e-09 37.1 0.0 4.2e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 Regulated-SNARE-like domain Syntaxin-6_N PF09177.11 KKK25246.1 - 0.12 12.9 0.1 0.22 12.1 0.1 1.3 1 0 0 1 1 1 0 Syntaxin 6, N-terminal MFS_1 PF07690.16 KKK25247.1 - 2.4e-33 115.5 27.4 2.4e-33 115.5 27.4 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF2070 PF09843.9 KKK25247.1 - 4.9 5.3 24.1 0.014 13.7 5.9 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2070) Glyco_hydro_18 PF00704.28 KKK25249.1 - 4.1e-68 230.4 2.7 4.1e-68 230.4 2.7 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 KKK25249.1 - 3e-09 37.2 11.1 3e-09 37.2 11.1 5.4 6 1 0 6 6 6 1 Chitin recognition protein Glyco_hydro_85 PF03644.13 KKK25249.1 - 0.018 14.5 0.0 0.03 13.7 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 85 zf-H2C2_2 PF13465.6 KKK25253.1 - 3.5e-14 52.5 34.3 9.7e-09 35.3 0.9 6.5 6 0 0 6 6 6 3 Zinc-finger double domain zf-C2H2 PF00096.26 KKK25253.1 - 1.9e-10 40.6 7.4 6.7e-07 29.4 1.8 6.4 6 0 0 6 6 6 4 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 KKK25253.1 - 8.8e-10 38.3 10.8 0.0011 19.0 0.5 4.2 3 0 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.7 KKK25253.1 - 2.4e-08 34.1 9.9 0.0019 18.5 0.2 4.4 3 0 0 3 3 3 3 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KKK25253.1 - 5.1e-07 29.8 2.9 0.024 14.9 0.1 4.5 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 KKK25253.1 - 1.4e-06 28.6 7.3 0.00021 21.9 1.2 7.8 8 0 0 8 8 8 4 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KKK25253.1 - 0.036 13.8 16.3 0.16 11.8 0.2 4.5 4 1 0 4 4 4 0 zinc-finger C2H2-type Paramyxo_NS_C PF02725.14 KKK25254.1 - 0.59 10.2 3.6 0.74 9.9 3.6 1.3 1 0 0 1 1 1 0 Non-structural protein C DUF4661 PF15576.6 KKK25254.1 - 0.78 9.6 9.4 0.98 9.3 9.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) Peptidase_S15 PF02129.18 KKK25254.1 - 1.1 8.8 9.3 1.3 8.6 9.0 1.3 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) WLM PF08325.10 KKK25254.1 - 1.2 9.1 8.1 2.5 8.1 8.0 1.7 1 1 0 1 1 1 0 WLM domain DEAD PF00270.29 KKK25255.1 - 1.9e-50 171.0 0.0 1e-49 168.7 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KKK25255.1 - 4.5e-27 94.6 0.0 1.9e-26 92.6 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KKK25255.1 - 0.0039 17.2 0.0 0.017 15.1 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HMG_box PF00505.19 KKK25256.1 - 2.1e-10 40.9 2.1 2.1e-10 40.9 2.1 3.3 3 1 0 3 3 3 2 HMG (high mobility group) box HMG_box_2 PF09011.10 KKK25256.1 - 2.2e-09 37.8 13.6 3.4e-07 30.7 0.6 3.0 3 0 0 3 3 3 2 HMG-box domain Ndc1_Nup PF09531.10 KKK25256.1 - 1.6 7.4 7.5 1.9 7.1 7.5 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup ALMT PF11744.8 KKK25256.1 - 8.9 5.0 7.2 12 4.6 7.2 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Sugar_tr PF00083.24 KKK25257.1 - 3.7e-102 342.5 18.4 4.3e-102 342.3 18.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKK25257.1 - 1.8e-28 99.5 28.4 2.9e-19 69.2 11.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily VEGFR-2_TMD PF17988.1 KKK25257.1 - 0.54 9.7 2.3 1.8 8.0 2.3 2.0 1 0 0 1 1 1 0 VEGFR-2 Transmembrane domain Alpha-L-AF_C PF06964.12 KKK25258.1 - 2.5e-30 105.8 0.1 3.6e-30 105.3 0.1 1.2 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminal domain Glyco_hydro_44 PF12891.7 KKK25258.1 - 0.061 13.3 1.0 0.2 11.6 1.0 1.8 1 1 0 1 1 1 0 Glycoside hydrolase family 44 CK_II_beta PF01214.18 KKK25259.1 - 3.6e-75 251.8 0.1 4.9e-75 251.3 0.1 1.2 1 0 0 1 1 1 1 Casein kinase II regulatory subunit CxC5 PF18718.1 KKK25259.1 - 0.064 13.3 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 CxC5 like cysteine cluster associated with KDZ transposases Uso1_p115_C PF04871.13 KKK25259.1 - 0.9 9.9 5.6 1.7 9.0 5.6 1.4 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region Abhydrolase_6 PF12697.7 KKK25260.1 - 3.1e-06 27.9 3.0 3.2e-05 24.6 0.1 2.1 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 KKK25260.1 - 0.041 13.7 0.2 0.19 11.6 0.0 2.1 2 1 1 3 3 3 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KKK25260.1 - 0.047 12.9 0.0 0.2 10.9 0.0 1.9 2 0 0 2 2 2 0 Serine aminopeptidase, S33 JAB PF01398.21 KKK25261.1 - 2.3e-08 34.0 1.3 6.9e-07 29.3 0.5 2.6 2 1 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Inhibitor_I78 PF11720.8 KKK25262.1 - 1.6e-09 37.6 0.0 2.6e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase inhibitor I78 family potato_inhibit PF00280.18 KKK25262.1 - 0.00021 21.9 0.0 0.00029 21.4 0.0 1.3 1 0 0 1 1 1 1 Potato inhibitor I family Nefa_Nip30_N PF10187.9 KKK25263.1 - 3.4e-32 110.9 13.3 3.4e-32 110.9 13.3 2.4 2 1 0 2 2 2 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 ALS2CR11 PF15729.5 KKK25263.1 - 0.31 10.1 10.1 0.4 9.8 10.1 1.1 1 0 0 1 1 1 0 Amyotrophic lateral sclerosis 2 candidate 11 Aldo_ket_red PF00248.21 KKK25264.1 - 1.3e-40 139.4 0.0 8.3e-39 133.5 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Glyco_hydro_6 PF01341.17 KKK25265.1 - 7.7e-105 351.0 0.2 1.1e-104 350.5 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 DUF737 PF05300.11 KKK25266.1 - 0.0053 17.2 12.8 0.0053 17.2 12.8 8.5 4 1 0 4 4 4 1 Protein of unknown function (DUF737) SGTA_dimer PF16546.5 KKK25267.1 - 2.7e-26 91.1 0.4 4.8e-26 90.3 0.4 1.4 1 0 0 1 1 1 1 Homodimerisation domain of SGTA TPR_1 PF00515.28 KKK25267.1 - 9.2e-13 47.4 6.8 0.00076 19.2 0.2 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KKK25267.1 - 5.2e-12 44.9 9.1 0.0042 17.1 0.8 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 KKK25267.1 - 3e-08 33.2 8.2 0.0018 18.3 0.1 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 KKK25267.1 - 3.8e-08 32.9 7.0 1.6e-06 27.7 2.9 2.9 2 1 1 3 3 3 2 TPR repeat TPR_7 PF13176.6 KKK25267.1 - 1.1e-05 25.1 0.7 1.8 8.8 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 KKK25267.1 - 4.1e-05 24.0 4.4 0.001 19.5 3.0 2.5 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 KKK25267.1 - 7e-05 22.9 1.6 0.022 15.1 0.5 3.2 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 KKK25267.1 - 0.00038 21.1 12.0 0.0039 17.8 7.8 2.9 2 1 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 KKK25267.1 - 0.00039 20.5 4.2 0.013 15.6 0.7 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 KKK25267.1 - 0.00043 20.5 7.8 0.015 15.5 3.8 2.9 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 KKK25267.1 - 0.0025 18.5 7.0 0.12 13.2 0.3 3.7 1 1 2 3 3 3 1 Tetratricopeptide repeat STI1 PF17830.1 KKK25267.1 - 0.0032 17.4 10.8 0.027 14.4 6.3 2.7 2 0 0 2 2 2 1 STI1 domain XPC-binding PF09280.11 KKK25267.1 - 0.0051 16.5 5.2 0.019 14.7 5.2 1.9 1 1 0 1 1 1 1 XPC-binding domain GerD PF17898.1 KKK25267.1 - 0.025 14.5 0.5 0.69 9.9 0.2 2.8 3 0 0 3 3 3 0 Spore germination GerD central core domain TPR_10 PF13374.6 KKK25267.1 - 3 7.8 9.2 8.7 6.4 0.2 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 KKK25267.1 - 3.6 8.4 7.7 4.9 8.0 0.2 3.8 4 0 0 4 4 3 0 Tetratricopeptide repeat Mito_carr PF00153.27 KKK25268.1 - 1.3e-63 211.0 1.4 6.1e-22 77.4 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein GFA PF04828.14 KKK25269.1 - 7.3e-07 29.5 2.2 1.2e-06 28.7 2.2 1.4 1 1 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme PHD_Oberon PF07227.11 KKK25269.1 - 0.032 14.1 3.3 0.15 12.0 0.3 2.2 2 0 0 2 2 2 0 PHD - plant homeodomain finger protein Mod_r PF07200.13 KKK25270.1 - 8e-24 84.4 5.9 9.6e-24 84.2 5.9 1.1 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein Fib_alpha PF08702.10 KKK25270.1 - 0.032 14.4 0.4 0.069 13.3 0.4 1.5 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family GIT_CC PF16559.5 KKK25270.1 - 0.085 12.7 0.9 0.17 11.8 0.9 1.4 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor PSK_trans_fac PF07704.11 KKK25270.1 - 0.14 12.9 5.4 0.098 13.4 3.3 1.7 2 0 0 2 2 2 0 Rv0623-like transcription factor Na_H_Exchanger PF00999.21 KKK25271.1 - 3.2e-60 203.9 45.6 4.5e-60 203.4 45.6 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Usp PF00582.26 KKK25271.1 - 0.0047 17.5 0.0 0.1 13.1 0.0 2.5 2 0 0 2 2 2 1 Universal stress protein family CHCH PF06747.13 KKK25272.1 - 0.00017 21.6 0.9 0.00026 21.1 0.9 1.3 1 0 0 1 1 1 1 CHCH domain COX17 PF05051.13 KKK25272.1 - 0.0077 16.6 2.4 0.44 10.9 0.3 2.2 1 1 1 2 2 2 2 Cytochrome C oxidase copper chaperone (COX17) Pet191_N PF10203.9 KKK25272.1 - 0.016 15.5 2.7 0.1 12.9 2.7 2.0 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 NDUF_B7 PF05676.13 KKK25272.1 - 0.081 12.7 0.4 0.11 12.2 0.4 1.2 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) ANKH PF07260.11 KKK25272.1 - 0.2 10.8 0.0 0.24 10.5 0.0 1.1 1 0 0 1 1 1 0 Progressive ankylosis protein (ANKH) Got1 PF04178.12 KKK25273.1 - 9.3e-33 113.0 18.3 1.8e-32 112.1 18.3 1.4 1 1 0 1 1 1 1 Got1/Sft2-like family HLH PF00010.26 KKK25274.1 - 3.3e-12 46.2 0.0 1.3e-11 44.2 0.0 2.0 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF4554 PF15091.6 KKK25274.1 - 0.22 10.4 0.6 0.32 9.8 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) Ank_5 PF13857.6 KKK25275.1 - 4.4e-11 42.8 0.1 5.5e-08 32.9 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 KKK25275.1 - 5.2e-10 39.7 0.1 4.2e-06 27.2 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KKK25275.1 - 8.3e-08 32.7 0.2 1.4e-07 32.0 0.2 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KKK25275.1 - 2.5e-07 30.5 1.0 2.5e-05 24.3 0.1 3.2 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.30 KKK25275.1 - 0.0021 18.4 0.5 0.011 16.2 0.1 2.4 3 0 0 3 3 3 1 Ankyrin repeat YejG PF13989.6 KKK25275.1 - 0.024 15.1 0.0 0.042 14.3 0.0 1.4 1 0 0 1 1 1 0 YejG-like protein tRNA_lig_CPD PF08302.11 KKK25276.1 - 8.2e-87 290.8 0.0 1.2e-86 290.3 0.0 1.2 1 0 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain RNA_lig_T4_1 PF09511.10 KKK25276.1 - 2.5e-84 282.6 0.0 5.2e-84 281.5 0.0 1.6 1 0 0 1 1 1 1 RNA ligase tRNA_lig_kinase PF08303.11 KKK25276.1 - 2.3e-52 177.5 0.0 3.9e-52 176.7 0.0 1.4 1 0 0 1 1 1 1 tRNA ligase kinase domain AAA_18 PF13238.6 KKK25276.1 - 0.084 13.4 0.3 1.6 9.2 0.1 3.0 2 1 1 3 3 3 0 AAA domain NPR3 PF03666.13 KKK25277.1 - 1.9e-156 521.5 3.3 1.5e-154 515.2 0.0 2.1 2 0 0 2 2 2 2 Nitrogen Permease regulator of amino acid transport activity 3 La PF05383.17 KKK25278.1 - 2.3e-20 72.4 0.5 4.1e-20 71.6 0.5 1.4 1 0 0 1 1 1 1 La domain TatD_DNase PF01026.21 KKK25279.1 - 1.9e-47 161.8 0.0 2.3e-47 161.5 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase Ank_5 PF13857.6 KKK25280.1 - 1e-16 60.7 0.1 2.3e-11 43.7 0.0 5.1 5 1 0 5 5 5 2 Ankyrin repeats (many copies) VPS9 PF02204.18 KKK25280.1 - 7.4e-16 58.2 0.0 1.6e-15 57.2 0.0 1.5 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Ank_2 PF12796.7 KKK25280.1 - 6.4e-14 52.3 0.0 4.6e-05 23.9 0.0 3.9 1 1 3 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KKK25280.1 - 4.5e-08 33.5 0.0 0.0093 16.5 0.0 5.4 5 1 1 6 6 6 2 Ankyrin repeats (many copies) PX PF00787.24 KKK25280.1 - 5.1e-08 32.9 0.6 5.1e-08 32.9 0.6 2.0 2 0 0 2 2 2 1 PX domain Ank_3 PF13606.6 KKK25280.1 - 2.1e-05 24.5 0.1 6.2 7.7 0.0 5.8 5 0 0 5 5 5 1 Ankyrin repeat Ank PF00023.30 KKK25280.1 - 0.002 18.5 0.0 7 7.3 0.0 4.2 5 0 0 5 5 5 1 Ankyrin repeat Ribosomal_S11 PF00411.19 KKK25280.1 - 0.0058 17.0 0.0 0.025 15.0 0.0 2.1 2 0 0 2 2 2 1 Ribosomal protein S11 RasGEF PF00617.19 KKK25280.1 - 0.036 14.3 0.1 0.09 13.0 0.1 1.7 1 0 0 1 1 1 0 RasGEF domain Tim44 PF04280.15 KKK25281.1 - 1.3e-37 129.2 0.1 6.1e-37 127.0 0.0 1.9 2 0 0 2 2 2 1 Tim44-like domain DUF3347 PF11827.8 KKK25281.1 - 0.24 11.5 3.5 0.17 12.0 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3347) RIC1 PF07064.13 KKK25282.1 - 1.5e-83 280.1 0.0 2.2e-83 279.5 0.0 1.2 1 0 0 1 1 1 1 RIC1 YchF-GTPase_C PF06071.13 KKK25283.1 - 8.1e-33 112.5 0.4 2.7e-32 110.8 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF933) Pre-PUA PF17832.1 KKK25283.1 - 1.1e-18 67.6 0.3 2.8e-18 66.4 0.3 1.6 1 0 0 1 1 1 1 Pre-PUA-like domain MMR_HSR1 PF01926.23 KKK25283.1 - 1.1e-16 60.9 0.0 3.6e-16 59.3 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase PUA PF01472.20 KKK25283.1 - 2.6e-14 52.9 0.1 7.9e-14 51.4 0.1 1.9 1 0 0 1 1 1 1 PUA domain FeoB_N PF02421.18 KKK25283.1 - 0.00038 20.0 0.0 0.00074 19.1 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B TGS PF02824.21 KKK25283.1 - 0.0029 17.6 0.1 0.016 15.2 0.1 2.2 2 0 0 2 2 2 1 TGS domain AAA_14 PF13173.6 KKK25283.1 - 0.097 12.7 0.0 0.33 11.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain Hira PF07569.11 KKK25284.1 - 1.3e-84 283.4 0.0 2.6e-84 282.4 0.0 1.5 1 0 0 1 1 1 1 TUP1-like enhancer of split WD40 PF00400.32 KKK25284.1 - 2.7e-25 88.1 18.6 4.2e-05 24.2 0.0 9.3 9 1 0 9 9 9 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKK25284.1 - 3.6e-11 43.2 0.0 0.063 13.6 0.0 5.2 3 1 3 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain HIRA_B PF09453.10 KKK25284.1 - 1.5e-10 40.7 0.1 3.4e-10 39.5 0.1 1.7 1 0 0 1 1 1 1 HIRA B motif PD40 PF07676.12 KKK25284.1 - 1.1e-05 25.2 2.0 0.44 10.5 0.0 5.3 5 0 0 5 5 5 2 WD40-like Beta Propeller Repeat IKI3 PF04762.12 KKK25284.1 - 0.11 10.4 0.1 0.36 8.8 0.0 1.7 2 0 0 2 2 2 0 IKI3 family Band_7 PF01145.25 KKK25285.1 - 5.9e-31 107.8 0.7 1.4e-30 106.6 0.7 1.6 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_C PF16200.5 KKK25285.1 - 1.8e-23 82.3 1.3 1.8e-23 82.3 1.3 2.0 2 0 0 2 2 2 1 C-terminal region of band_7 Pox_A11 PF05061.13 KKK25285.1 - 0.085 12.1 0.2 0.12 11.6 0.2 1.2 1 0 0 1 1 1 0 Poxvirus A11 Protein Band_7_1 PF13421.6 KKK25285.1 - 0.096 12.4 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 SPFH domain-Band 7 family GSH-S_N PF02951.14 KKK25285.1 - 0.11 12.6 0.1 0.53 10.4 0.1 2.1 2 1 0 2 2 2 0 Prokaryotic glutathione synthetase, N-terminal domain HSP70 PF00012.20 KKK25354.1 - 2e-258 858.5 12.8 2.3e-258 858.3 12.8 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KKK25354.1 - 3.2e-17 62.3 2.0 4e-16 58.8 0.7 2.1 2 0 0 2 2 2 1 MreB/Mbl protein DUF1464 PF07318.12 KKK25354.1 - 0.0031 16.7 1.1 0.41 9.8 0.1 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1464) DDR PF08841.10 KKK25354.1 - 0.0045 16.0 0.4 0.013 14.5 0.2 1.8 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain Hydantoinase_A PF01968.18 KKK25354.1 - 0.13 11.5 4.6 0.31 10.3 0.1 2.8 3 0 0 3 3 3 0 Hydantoinase/oxoprolinase FIVAR PF07554.13 KKK25354.1 - 0.35 11.6 7.2 16 6.3 2.2 3.9 3 1 0 3 3 3 0 FIVAR domain FtsA PF14450.6 KKK25354.1 - 3.3 8.2 7.4 17 5.9 0.2 3.5 3 2 0 3 3 3 0 Cell division protein FtsA Haem_degrading PF03928.14 KKK25355.1 - 6.8e-34 116.5 0.1 9e-34 116.1 0.1 1.2 1 0 0 1 1 1 1 Haem-degrading GTP_EFTU PF00009.27 KKK25356.1 - 5.3e-50 169.7 0.1 8.4e-50 169.0 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain HBS1_N PF08938.10 KKK25356.1 - 2.4e-16 59.8 3.5 5.3e-16 58.7 3.5 1.5 1 0 0 1 1 1 1 HBS1 N-terminus MMR_HSR1 PF01926.23 KKK25356.1 - 2.7e-08 33.9 0.2 1.4e-06 28.3 0.0 2.9 2 1 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU_D3 PF03143.17 KKK25356.1 - 4.6e-08 33.3 0.0 1.8e-07 31.4 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 KKK25356.1 - 2.4e-06 27.9 0.0 6.6e-06 26.4 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Gtr1_RagA PF04670.12 KKK25356.1 - 0.00025 20.5 0.1 0.00061 19.2 0.1 1.6 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 KKK25356.1 - 0.00045 19.7 0.1 0.13 11.7 0.0 2.5 1 1 1 2 2 2 2 Signal recognition particle receptor beta subunit Arf PF00025.21 KKK25356.1 - 0.0086 15.5 0.2 2.6 7.5 0.0 2.4 1 1 1 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 KKK25356.1 - 0.011 15.9 0.1 2.7 8.2 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase FeoB_N PF02421.18 KKK25356.1 - 0.041 13.4 0.7 1.4 8.4 0.4 2.9 2 1 0 2 2 2 0 Ferrous iron transport protein B Septin PF00735.18 KKK25356.1 - 0.062 12.6 0.0 0.12 11.6 0.0 1.5 1 0 0 1 1 1 0 Septin Acyltransf_C PF16076.5 KKK25356.1 - 0.13 12.4 0.0 0.32 11.1 0.0 1.7 1 0 0 1 1 1 0 Acyltransferase C-terminus Na_Ca_ex PF01699.24 KKK25371.1 - 1.2e-41 142.2 40.0 3.6e-22 79.0 18.9 2.1 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Neurokinin_B PF03823.14 KKK25371.1 - 0.11 12.5 0.1 0.64 10.1 0.1 2.4 1 0 0 1 1 1 0 Neurokinin B Trypan_PARP PF05887.11 KKK25371.1 - 0.29 11.1 4.0 2.7 8.0 1.9 2.5 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Fungal_trans PF04082.18 KKK25372.1 - 2.6e-18 66.0 0.0 6.7e-18 64.7 0.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK25372.1 - 5.8e-05 23.1 7.6 0.00011 22.2 7.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain gag-asp_proteas PF13975.6 KKK25373.1 - 0.0029 18.1 0.0 0.0053 17.3 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.20 KKK25373.1 - 0.027 14.8 0.0 0.049 14.0 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease Asp_protease_2 PF13650.6 KKK25373.1 - 0.16 12.6 0.0 0.32 11.7 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease PIG-X PF08320.12 KKK25380.1 - 6.9e-74 248.3 0.0 9.6e-74 247.8 0.0 1.2 1 0 0 1 1 1 1 PIG-X / PBN1 Dsl1_N PF11988.8 KKK25380.1 - 0.3 10.0 0.0 0.43 9.5 0.0 1.1 1 0 0 1 1 1 0 Retrograde transport protein Dsl1 N terminal Zn_clus PF00172.18 KKK25381.1 - 1.7e-08 34.5 9.6 2.8e-08 33.7 9.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KKK25381.1 - 3.9e-07 29.4 0.0 1.1e-06 27.9 0.0 1.7 1 1 1 2 2 2 1 Fungal specific transcription factor domain IMUP PF15761.5 KKK25381.1 - 2.8 8.7 7.6 5.4 7.8 7.6 1.4 1 0 0 1 1 1 0 Immortalisation up-regulated protein DnaJ_C PF01556.18 KKK25382.1 - 6.5e-36 123.6 0.4 7.8e-36 123.4 0.4 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain HGTP_anticodon2 PF12745.7 KKK25383.1 - 5.2e-85 285.1 0.4 7.3e-85 284.6 0.4 1.2 1 0 0 1 1 1 1 Anticodon binding domain of tRNAs Pkinase PF00069.25 KKK25383.1 - 1.4e-31 109.8 0.0 2.5e-31 109.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK25383.1 - 5.5e-17 61.9 0.0 9.8e-17 61.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase tRNA-synt_His PF13393.6 KKK25383.1 - 5.7e-11 42.2 0.0 9.3e-11 41.5 0.0 1.3 1 0 0 1 1 1 1 Histidyl-tRNA synthetase APH PF01636.23 KKK25383.1 - 0.00063 19.7 0.2 0.0017 18.4 0.2 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family HGTP_anticodon PF03129.20 KKK25383.1 - 0.024 14.8 0.0 0.055 13.6 0.0 1.6 1 0 0 1 1 1 0 Anticodon binding domain HIF-1a_CTAD PF08778.10 KKK25383.1 - 0.17 11.5 0.1 0.59 9.8 0.1 1.9 1 0 0 1 1 1 0 HIF-1 alpha C terminal transactivation domain MMR_HSR1_Xtn PF16897.5 KKK25385.1 - 4e-35 120.0 1.1 1.3e-34 118.4 0.4 2.0 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 KKK25385.1 - 5.6e-21 74.4 0.1 9.8e-21 73.6 0.1 1.4 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.23 KKK25385.1 - 1.7e-20 73.2 0.1 5.6e-20 71.5 0.0 1.9 1 1 1 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KKK25385.1 - 1.1e-11 44.6 0.0 1.7e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 KKK25385.1 - 0.00013 22.1 0.2 0.086 12.9 0.0 2.5 1 1 1 2 2 2 2 Dynamin family AIG1 PF04548.16 KKK25385.1 - 0.027 13.8 0.0 0.044 13.1 0.0 1.3 1 0 0 1 1 1 0 AIG1 family Roc PF08477.13 KKK25385.1 - 0.035 14.3 0.2 2 8.7 0.0 2.4 2 1 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Rhabdo_ncap PF00945.18 KKK25385.1 - 0.047 12.6 0.1 0.064 12.1 0.1 1.1 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein MCM PF00493.23 KKK25385.1 - 0.047 12.8 0.1 0.12 11.5 0.0 1.6 2 0 0 2 2 2 0 MCM P-loop domain MeaB PF03308.16 KKK25385.1 - 0.055 12.4 0.1 0.11 11.5 0.1 1.5 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Torus PF16131.5 KKK25386.1 - 9.7e-46 155.0 0.4 2.6e-45 153.6 0.0 2.0 2 0 0 2 2 2 1 Torus domain RRM_1 PF00076.22 KKK25386.1 - 8.4e-09 35.1 0.0 1.9e-08 34.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf_CCCH_4 PF18345.1 KKK25386.1 - 0.00023 21.1 1.1 0.00041 20.3 1.1 1.4 1 0 0 1 1 1 1 Zinc finger domain Nup35_RRM_2 PF14605.6 KKK25386.1 - 0.006 16.6 0.0 0.011 15.7 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif zf-CCCH PF00642.24 KKK25386.1 - 0.076 13.0 1.6 0.13 12.2 1.6 1.4 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Alpha_Helical PF18489.1 KKK25386.1 - 0.1 12.8 0.0 0.18 12.0 0.0 1.3 1 0 0 1 1 1 0 Alpha helical domain P-II PF00543.22 KKK25386.1 - 0.15 12.7 0.0 0.32 11.6 0.0 1.5 1 0 0 1 1 1 0 Nitrogen regulatory protein P-II GATase PF00117.28 KKK25388.1 - 1.2e-46 158.9 0.0 1.7e-46 158.4 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_sm_chain PF00988.22 KKK25388.1 - 4.8e-46 155.7 0.0 9.8e-46 154.7 0.0 1.5 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase small chain, CPSase domain Peptidase_C26 PF07722.13 KKK25388.1 - 2.1e-05 24.4 0.1 0.00047 20.0 0.1 2.4 1 1 0 1 1 1 1 Peptidase C26 DJ-1_PfpI PF01965.24 KKK25388.1 - 0.023 14.5 0.0 0.04 13.7 0.0 1.4 1 0 0 1 1 1 0 DJ-1/PfpI family S4 PF01479.25 KKK25410.1 - 1.1e-12 47.5 0.1 2.1e-12 46.6 0.1 1.4 1 0 0 1 1 1 1 S4 domain Ribosomal_S4 PF00163.19 KKK25410.1 - 1.1e-09 39.0 0.9 1.6e-09 38.5 0.9 1.4 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain PilP PF04351.13 KKK25410.1 - 0.085 12.8 0.1 0.18 11.7 0.0 1.5 1 1 0 1 1 1 0 Pilus assembly protein, PilP DUF4449 PF14613.6 KKK25411.1 - 9.6e-05 22.5 0.1 9.6e-05 22.5 0.1 3.4 3 1 1 4 4 4 1 Protein of unknown function (DUF4449) Tricorn_C1 PF14684.6 KKK25411.1 - 0.00056 19.9 0.1 0.0025 17.9 0.1 2.1 2 0 0 2 2 2 1 Tricorn protease C1 domain AbiH PF14253.6 KKK25411.1 - 0.19 11.6 0.5 0.33 10.8 0.5 1.4 1 0 0 1 1 1 0 Bacteriophage abortive infection AbiH Gp-FAR-1 PF05823.12 KKK25411.1 - 1.2 9.4 4.5 4.4 7.6 0.3 2.7 1 1 1 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Com_YlbF PF06133.11 KKK25411.1 - 2.5 8.8 7.2 10 6.8 1.0 3.2 1 1 2 3 3 3 0 Control of competence regulator ComK, YlbF/YmcA DnaJ PF00226.31 KKK25412.1 - 1.3e-26 92.5 2.1 2.1e-26 91.8 2.1 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_C PF01556.18 KKK25412.1 - 2.7e-25 89.2 0.0 4.1e-25 88.6 0.0 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.19 KKK25412.1 - 8.3e-15 54.9 14.0 1.3e-14 54.3 14.0 1.3 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 KKK25412.1 - 2e-06 27.7 6.3 0.0005 20.0 0.7 2.4 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 KKK25412.1 - 0.08 13.0 6.5 1.3 9.1 0.2 2.3 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA GRP PF07172.11 KKK25412.1 - 4.5 8.0 8.8 18 6.1 8.8 2.0 1 1 0 1 1 1 0 Glycine rich protein family zf-CSL PF05207.13 KKK25412.1 - 5.1 6.9 6.0 7 6.5 0.6 2.4 2 0 0 2 2 2 0 CSL zinc finger Lar_restr_allev PF14354.6 KKK25412.1 - 5.2 7.5 10.4 3.6 8.0 1.8 3.3 1 1 2 3 3 3 0 Restriction alleviation protein Lar Glyco_hydro_3_C PF01915.22 KKK25434.1 - 4.2e-49 167.3 0.0 7.7e-49 166.4 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KKK25434.1 - 1.3e-37 129.9 0.0 2.5e-37 129.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KKK25434.1 - 3.1e-12 46.4 0.1 6.2e-12 45.5 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain bZIP_1 PF00170.21 KKK25435.1 - 0.006 16.7 10.7 0.034 14.2 10.7 1.9 1 1 1 2 2 2 1 bZIP transcription factor RskA PF10099.9 KKK25450.1 - 0.043 14.1 5.6 0.38 11.0 0.1 2.7 2 1 0 2 2 2 0 Anti-sigma-K factor rskA HSBP1 PF06825.12 KKK25450.1 - 0.061 13.2 0.2 0.19 11.6 0.0 1.9 2 0 0 2 2 2 0 Heat shock factor binding protein 1 Exo_endo_phos PF03372.23 KKK25451.1 - 4.1e-09 36.3 0.0 7.3e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DCP1 PF06058.13 KKK25452.1 - 4.6e-27 94.3 0.0 7.5e-27 93.6 0.0 1.3 1 0 0 1 1 1 1 Dcp1-like decapping family MAGI_u1 PF16663.5 KKK25452.1 - 0.6 10.2 2.5 3.7 7.7 0.2 2.5 2 0 0 2 2 2 0 Unstructured region on MAGI LIDHydrolase PF10230.9 KKK25453.1 - 1.7e-78 263.8 0.0 5.8e-78 262.1 0.0 1.8 1 1 0 1 1 1 1 Lipid-droplet associated hydrolase Abhydrolase_6 PF12697.7 KKK25453.1 - 2.9e-06 28.1 0.4 0.0015 19.2 0.1 2.2 2 0 0 2 2 2 2 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KKK25453.1 - 0.00031 20.1 0.1 0.00083 18.7 0.1 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DUF1057 PF06342.12 KKK25453.1 - 0.023 13.7 0.0 0.42 9.6 0.0 2.2 1 1 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) DUF900 PF05990.12 KKK25453.1 - 0.028 13.9 0.0 0.056 13.0 0.0 1.5 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) Thioesterase PF00975.20 KKK25453.1 - 0.051 13.7 0.0 0.21 11.7 0.0 2.0 2 0 0 2 2 2 0 Thioesterase domain PGAP1 PF07819.13 KKK25453.1 - 0.17 11.5 0.1 0.55 9.9 0.0 1.8 2 0 0 2 2 2 0 PGAP1-like protein SMK-1 PF04802.15 KKK25454.1 - 1.9e-78 262.7 1.2 3.2e-78 262.0 1.2 1.4 1 0 0 1 1 1 1 Component of IIS longevity pathway SMK-1 CALM_bind PF16025.5 KKK25455.1 - 0.078 13.5 6.3 0.18 12.3 6.3 1.6 1 0 0 1 1 1 0 Calcium-dependent calmodulin binding POT1PC PF16686.5 KKK25466.1 - 3.4e-44 150.4 0.1 5.8e-44 149.7 0.1 1.4 1 0 0 1 1 1 1 ssDNA-binding domain of telomere protection protein POT1 PF02765.17 KKK25466.1 - 0.14 12.0 0.0 0.32 10.8 0.0 1.6 1 0 0 1 1 1 0 Telomeric single stranded DNA binding POT1/CDC13 SWIRM-assoc_2 PF16496.5 KKK25466.1 - 1.7 7.4 7.8 2.5 6.9 7.8 1.2 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal Pneumo_att_G PF05539.11 KKK25466.1 - 2.5 7.6 4.8 3.7 7.0 4.8 1.1 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G Arm PF00514.23 KKK25467.1 - 2.4e-95 310.0 11.9 4.1e-14 52.0 0.0 8.2 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat IBB PF01749.20 KKK25467.1 - 3.6e-27 94.6 3.4 9.4e-27 93.3 3.4 1.7 1 0 0 1 1 1 1 Importin beta binding domain Arm_3 PF16186.5 KKK25467.1 - 8e-24 83.0 3.2 1.8e-23 81.8 3.2 1.6 1 0 0 1 1 1 1 Atypical Arm repeat HEAT_EZ PF13513.6 KKK25467.1 - 7.2e-21 74.3 4.9 1.5e-09 38.2 0.1 6.1 4 1 2 6 6 6 4 HEAT-like repeat HEAT_2 PF13646.6 KKK25467.1 - 1.1e-19 70.6 0.1 4e-09 36.7 0.0 5.0 1 1 4 5 5 5 4 HEAT repeats HEAT PF02985.22 KKK25467.1 - 4.2e-19 67.0 0.3 3.5e-06 26.8 0.0 6.9 7 0 0 7 7 7 4 HEAT repeat Arm_2 PF04826.13 KKK25467.1 - 6.8e-09 35.6 0.0 0.0028 17.2 0.0 4.0 2 1 2 4 4 4 2 Armadillo-like Adaptin_N PF01602.20 KKK25467.1 - 3.2e-06 26.0 0.0 0.00058 18.5 0.0 2.2 1 1 1 2 2 2 2 Adaptin N terminal region V-ATPase_H_C PF11698.8 KKK25467.1 - 1.2e-05 25.4 0.0 0.8 9.8 0.0 4.4 3 2 2 5 5 5 2 V-ATPase subunit H Cnd1 PF12717.7 KKK25467.1 - 0.0019 18.2 0.0 3.9 7.5 0.0 3.1 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_PBS PF03130.16 KKK25467.1 - 0.0092 16.6 4.7 0.77 10.6 0.0 4.6 5 0 0 5 5 5 1 PBS lyase HEAT-like repeat RICTOR_V PF14668.6 KKK25467.1 - 0.013 15.7 3.0 0.98 9.7 0.0 4.6 4 2 2 6 6 6 0 Rapamycin-insensitive companion of mTOR, domain 5 Gcn1_N PF12074.8 KKK25467.1 - 0.038 13.3 0.0 5.7 6.1 0.0 2.7 2 1 1 3 3 3 0 Generalcontrol nonderepressible 1 (Gcn1) N-terminal NopRA1 PF16201.5 KKK25467.1 - 0.09 12.3 0.0 49 3.4 0.0 3.5 1 1 3 4 4 4 0 Nucleolar pre-ribosomal-associated protein 1 Nha1_C PF08619.10 KKK25467.1 - 0.15 11.3 3.5 0.22 10.7 3.5 1.2 1 0 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus zf-CCCH_2 PF14608.6 KKK25468.1 - 0.0053 17.2 0.6 0.0053 17.2 0.6 2.9 3 0 0 3 3 3 1 RNA-binding, Nab2-type zinc finger Haemadin PF09065.10 KKK25468.1 - 0.034 13.9 4.7 4.4 7.2 0.1 3.0 2 1 0 2 2 2 0 Haemadin zf-CCHH PF10283.9 KKK25468.1 - 0.78 9.8 10.4 3.5 7.7 0.4 3.4 3 0 0 3 3 3 0 PBZ domain TRAP_alpha PF03896.16 KKK25469.1 - 2.1e-13 50.1 1.5 3.5e-13 49.4 1.5 1.4 1 1 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit DUF1616 PF07760.11 KKK25469.1 - 0.02 14.3 0.0 0.028 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1616) PepSY_TM PF03929.16 KKK25469.1 - 0.049 13.3 0.3 0.15 11.7 0.0 1.8 2 1 1 3 3 3 0 PepSY-associated TM region zf-C2HE PF16278.5 KKK25470.1 - 3.5e-18 65.8 0.4 9.2e-18 64.5 0.4 1.8 1 0 0 1 1 1 1 C2HE / C2H2 / C2HC zinc-binding finger DcpS_C PF11969.8 KKK25470.1 - 1.1e-15 58.0 5.9 3.3e-14 53.3 5.9 2.2 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 KKK25470.1 - 1.2e-15 58.0 0.0 2.8e-15 56.8 0.0 1.6 1 1 0 1 1 1 1 HIT domain HA2 PF04408.23 KKK25471.1 - 1e-16 61.1 1.2 2.6e-16 59.8 0.0 2.3 3 0 0 3 3 3 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KKK25471.1 - 7.9e-16 58.2 0.0 1.6e-15 57.2 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KKK25471.1 - 1.6e-12 47.7 0.0 5.7e-12 46.0 0.0 2.0 2 0 0 2 2 1 1 Helicase conserved C-terminal domain RWD PF05773.22 KKK25471.1 - 2.8e-12 46.9 0.2 7.8e-12 45.5 0.0 1.9 2 0 0 2 2 1 1 RWD domain DEAD PF00270.29 KKK25471.1 - 1.8e-09 37.7 0.1 3.3e-09 36.8 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase T2SSE PF00437.20 KKK25471.1 - 0.0021 17.2 0.0 0.0042 16.2 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_29 PF13555.6 KKK25471.1 - 0.015 15.1 0.0 0.036 13.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATPase PF06745.13 KKK25471.1 - 0.019 14.3 0.1 0.039 13.3 0.1 1.4 1 0 0 1 1 1 0 KaiC AAA_22 PF13401.6 KKK25471.1 - 0.023 14.9 3.4 0.55 10.5 3.4 2.4 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 KKK25471.1 - 0.034 13.6 0.0 0.064 12.7 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein DND1_DSRM PF14709.7 KKK25471.1 - 0.11 12.8 0.2 0.42 10.9 0.0 2.1 2 0 0 2 2 2 0 double strand RNA binding domain from DEAD END PROTEIN 1 AAA_30 PF13604.6 KKK25471.1 - 0.94 9.2 3.2 0.54 10.0 0.3 2.0 2 1 0 2 2 2 0 AAA domain AAA_23 PF13476.6 KKK25471.1 - 3.1 8.2 4.5 0.44 11.0 0.1 1.8 2 0 0 2 2 1 0 AAA domain Cyclin_N PF00134.23 KKK25472.1 - 3.8e-45 152.7 0.2 8.2e-45 151.6 0.2 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KKK25472.1 - 2.1e-31 108.5 0.3 6.5e-31 106.9 0.1 2.0 2 0 0 2 2 2 1 Cyclin, C-terminal domain Zn_clus PF00172.18 KKK25473.1 - 0.0017 18.4 12.2 0.0034 17.5 12.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CHZ PF09649.10 KKK25473.1 - 0.16 11.5 0.1 0.39 10.2 0.1 1.7 1 0 0 1 1 1 0 Histone chaperone domain CHZ GTP_EFTU PF00009.27 KKK25479.1 - 3e-40 137.8 0.2 3.4e-40 137.7 0.2 1.0 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KKK25479.1 - 5.4e-05 23.2 0.1 0.0018 18.4 0.1 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 KKK25479.1 - 0.034 13.3 0.1 0.15 11.2 0.0 1.8 1 1 1 2 2 2 0 G-protein alpha subunit FtsK_SpoIIIE PF01580.18 KKK25479.1 - 0.036 13.4 0.1 0.3 10.4 0.1 1.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family AIG1 PF04548.16 KKK25479.1 - 0.04 13.2 0.6 0.47 9.7 0.6 2.0 1 1 0 1 1 1 0 AIG1 family SRPRB PF09439.10 KKK25479.1 - 0.046 13.2 0.1 0.52 9.7 0.1 2.1 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Dynamin_N PF00350.23 KKK25479.1 - 0.078 13.0 0.1 4.1 7.4 0.1 2.1 2 0 0 2 2 2 0 Dynamin family Septin PF00735.18 KKK25479.1 - 0.084 12.1 0.1 0.26 10.5 0.1 1.7 1 1 0 1 1 1 0 Septin PduV-EutP PF10662.9 KKK25479.1 - 0.1 12.4 0.1 11 5.7 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Polyoma_lg_T_C PF06431.11 KKK25479.1 - 0.18 10.6 0.0 0.24 10.3 0.0 1.2 1 0 0 1 1 1 0 Polyomavirus large T antigen C-terminus Ank_3 PF13606.6 KKK25480.1 - 8.2e-08 31.9 0.0 0.033 14.7 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 KKK25480.1 - 1.2e-07 32.3 0.0 6.7e-07 29.8 0.0 2.1 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KKK25480.1 - 1.1e-06 28.7 0.1 0.0057 16.9 0.0 3.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KKK25480.1 - 1.9e-05 24.9 0.0 0.02 15.3 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 KKK25480.1 - 0.001 19.6 0.0 0.0028 18.2 0.0 1.8 1 1 0 1 1 1 1 Ankyrin repeats (many copies) TFIIS_C PF01096.18 KKK25481.1 - 1.1e-13 50.7 2.5 3.3e-13 49.2 0.2 2.1 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 KKK25481.1 - 0.0078 16.1 0.6 0.015 15.2 0.2 1.7 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit MAGE PF01454.19 KKK25482.1 - 3.2e-34 118.5 1.0 6.4e-34 117.5 0.0 1.8 2 0 0 2 2 2 1 MAGE family F-actin_cap_A PF01267.17 KKK25484.1 - 1.8e-92 309.6 0.0 2.3e-92 309.2 0.0 1.1 1 0 0 1 1 1 1 F-actin capping protein alpha subunit PEX11 PF05648.14 KKK25484.1 - 2.4e-31 108.9 0.0 9e-31 107.1 0.0 2.0 1 1 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) DUF3987 PF13148.6 KKK25484.1 - 0.047 12.7 0.0 0.083 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) CCP_MauG PF03150.14 KKK25484.1 - 0.056 14.1 0.0 0.13 12.9 0.0 1.6 1 0 0 1 1 1 0 Di-haem cytochrome c peroxidase DUF512 PF04459.12 KKK25484.1 - 0.063 12.5 0.0 6.6 6.0 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF512) Zn_clus PF00172.18 KKK25485.1 - 3.8e-07 30.1 10.8 8.9e-07 28.9 10.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KKK25485.1 - 7e-05 22.0 0.1 0.00012 21.2 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain HEAT_EZ PF13513.6 KKK25486.1 - 2.7e-21 75.7 5.6 3.9e-07 30.4 0.0 9.2 9 0 0 9 9 8 3 HEAT-like repeat HEAT_2 PF13646.6 KKK25486.1 - 6.8e-19 68.1 5.1 0.00099 19.5 0.0 7.6 5 2 2 7 7 7 5 HEAT repeats HEAT PF02985.22 KKK25486.1 - 3.1e-18 64.3 1.2 0.00052 20.0 0.1 8.7 9 0 0 9 9 7 2 HEAT repeat Cnd1 PF12717.7 KKK25486.1 - 1.9e-14 54.0 0.1 8.5e-06 25.9 0.0 4.3 4 0 0 4 4 4 3 non-SMC mitotic condensation complex subunit 1 IFRD PF05004.13 KKK25486.1 - 2.5e-10 40.0 0.0 0.00034 19.8 0.0 4.0 3 1 1 4 4 4 3 Interferon-related developmental regulator (IFRD) MMS19_C PF12460.8 KKK25486.1 - 2.6e-09 36.7 1.2 0.0002 20.6 0.0 3.2 3 0 0 3 3 3 2 RNAPII transcription regulator C-terminal IBN_N PF03810.19 KKK25486.1 - 4.3e-09 36.1 0.3 2e-07 30.8 0.0 3.1 3 0 0 3 3 2 1 Importin-beta N-terminal domain Vac14_Fab1_bd PF12755.7 KKK25486.1 - 4.9e-09 36.7 0.0 0.55 10.9 0.0 5.9 5 1 1 6 6 5 2 Vacuolar 14 Fab1-binding region Arm PF00514.23 KKK25486.1 - 1.1e-06 28.4 0.0 3.4 7.8 0.0 5.4 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat CLASP_N PF12348.8 KKK25486.1 - 2.1e-06 27.5 0.0 0.069 12.7 0.0 3.9 4 0 0 4 4 4 2 CLASP N terminal RIX1 PF08167.12 KKK25486.1 - 1.1e-05 25.2 0.0 0.024 14.4 0.0 2.7 2 0 0 2 2 2 2 rRNA processing/ribosome biogenesis UME PF08064.13 KKK25486.1 - 0.00012 22.0 0.0 1.3 9.0 0.0 5.0 3 2 2 5 5 5 1 UME (NUC010) domain RTP1_C1 PF10363.9 KKK25486.1 - 0.00013 22.1 1.8 4.7 7.4 0.0 5.0 4 1 0 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 Adaptin_N PF01602.20 KKK25486.1 - 0.00014 20.6 0.2 0.25 9.8 0.0 3.2 3 0 0 3 3 3 2 Adaptin N terminal region DRIM PF07539.12 KKK25486.1 - 0.00044 18.7 1.4 1.2 7.3 0.1 3.7 3 1 0 3 3 3 2 Down-regulated in metastasis ParcG PF10274.9 KKK25486.1 - 0.00086 19.5 0.5 0.051 13.7 0.1 3.2 3 1 1 4 4 4 1 Parkin co-regulated protein Sec7_N PF12783.7 KKK25486.1 - 0.0013 18.6 0.0 0.0098 15.8 0.0 2.5 2 1 0 2 2 1 1 Guanine nucleotide exchange factor in Golgi transport N-terminal V-ATPase_H_C PF11698.8 KKK25486.1 - 0.005 16.9 0.1 2.3 8.4 0.0 4.2 4 0 0 4 4 4 1 V-ATPase subunit H DUF577 PF04510.12 KKK25486.1 - 0.0055 16.6 0.0 0.051 13.5 0.0 2.6 3 0 0 3 3 3 1 Family of unknown function (DUF577) UNC45-central PF11701.8 KKK25486.1 - 0.013 15.5 0.2 0.26 11.3 0.2 3.2 3 1 1 4 4 3 0 Myosin-binding striated muscle assembly central NopRA1 PF16201.5 KKK25486.1 - 0.017 14.8 0.4 7.9 6.0 0.0 3.6 3 1 1 4 4 4 0 Nucleolar pre-ribosomal-associated protein 1 V-ATPase_H_N PF03224.14 KKK25486.1 - 0.022 14.1 0.7 4.6 6.4 0.0 3.7 3 1 0 3 3 3 0 V-ATPase subunit H Cohesin_HEAT PF12765.7 KKK25486.1 - 0.056 13.8 0.0 6.6 7.1 0.0 3.0 3 0 0 3 3 2 0 HEAT repeat associated with sister chromatid cohesion DUF4042 PF13251.6 KKK25486.1 - 0.12 12.1 0.1 2.1 8.0 0.0 3.1 3 1 0 3 3 3 0 Domain of unknown function (DUF4042) Tti2 PF10521.9 KKK25486.1 - 0.15 11.6 0.1 3.4 7.1 0.0 3.1 3 1 1 4 4 3 0 Tti2 family Pkinase PF00069.25 KKK25487.1 - 1.2e-24 87.1 0.0 4.5e-24 85.2 0.0 1.7 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK25487.1 - 1.2e-05 24.7 0.0 3.4e-05 23.2 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Ras PF00071.22 KKK25488.1 - 3.9e-31 107.8 0.2 5e-31 107.5 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KKK25488.1 - 1.4e-23 83.4 0.1 2.2e-23 82.7 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKK25488.1 - 1.2e-06 28.1 0.1 1.7e-06 27.6 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KKK25488.1 - 0.00022 20.6 0.2 0.0003 20.2 0.2 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DLIC PF05783.11 KKK25488.1 - 0.014 14.2 0.1 1.9 7.3 0.0 2.1 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) 2-Hacid_dh PF00389.30 KKK25489.1 - 1.4e-06 28.0 0.0 1.5e-06 27.9 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain DUF3431 PF11913.8 KKK25490.1 - 5.8e-69 232.2 0.0 6.8e-69 231.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) Recep_L_domain PF01030.24 KKK25491.1 - 0.00015 21.8 0.0 0.00034 20.7 0.0 1.6 1 1 0 1 1 1 1 Receptor L domain Ecm33 PF12454.8 KKK25491.1 - 0.013 15.7 0.1 0.045 13.9 0.1 2.0 1 0 0 1 1 1 0 GPI-anchored cell wall organization protein Myc_target_1 PF15179.6 KKK25491.1 - 0.03 14.2 0.0 0.053 13.4 0.0 1.4 1 0 0 1 1 1 0 Myc target protein 1 VSP PF03302.13 KKK25491.1 - 0.051 12.4 0.3 0.077 11.8 0.3 1.2 1 0 0 1 1 1 0 Giardia variant-specific surface protein DUF4690 PF15756.5 KKK25491.1 - 0.065 13.8 0.6 0.38 11.4 0.1 2.4 2 0 0 2 2 2 0 Small Novel Rich in Cartilage Amnionless PF14828.6 KKK25491.1 - 0.074 11.9 0.0 0.1 11.4 0.0 1.1 1 0 0 1 1 1 0 Amnionless DUF3147 PF11345.8 KKK25491.1 - 0.087 13.2 0.1 0.15 12.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3147) Stevor PF17410.2 KKK25491.1 - 0.23 10.9 0.1 0.35 10.4 0.1 1.2 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame FA_desaturase PF00487.24 KKK25492.1 - 2.2e-28 99.8 26.0 4.1e-28 98.9 26.0 1.4 1 1 0 1 1 1 1 Fatty acid desaturase WD40 PF00400.32 KKK25493.1 - 3.4e-16 59.3 8.3 5.3e-07 30.2 0.1 4.5 4 0 0 4 4 4 2 WD domain, G-beta repeat CAF1C_H4-bd PF12265.8 KKK25493.1 - 1.9e-15 56.9 0.0 1.8e-14 53.7 0.0 2.5 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex ANAPC4_WD40 PF12894.7 KKK25493.1 - 8.6e-09 35.6 1.5 0.00032 21.0 0.2 3.1 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain UL41A PF17591.2 KKK25493.1 - 0.19 11.8 0.0 0.53 10.4 0.0 1.7 1 0 0 1 1 1 0 Herpesvirus UL41A Fungal_trans PF04082.18 KKK25494.1 - 9.2e-21 74.1 0.0 1.4e-20 73.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK25494.1 - 3.7e-10 39.7 9.1 5.6e-10 39.2 9.1 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RTA1 PF04479.13 KKK25495.1 - 9.6e-59 198.5 10.4 9.6e-59 198.5 10.4 1.8 1 1 1 2 2 2 1 RTA1 like protein DUF3671 PF12420.8 KKK25495.1 - 0.15 12.2 7.7 1.1 9.4 0.4 3.6 2 2 0 2 2 2 0 Protein of unknown function DUF1980 PF09323.10 KKK25495.1 - 1.5 8.7 6.8 3.9 7.3 0.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) ADH_zinc_N PF00107.26 KKK25496.1 - 3.7e-21 75.4 0.1 6.4e-21 74.7 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KKK25496.1 - 2.9e-19 70.5 0.0 4.4e-19 69.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KKK25496.1 - 4e-10 39.6 0.0 3.2e-09 36.6 0.0 2.1 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Aldo_ket_red PF00248.21 KKK25497.1 - 7.4e-38 130.4 0.0 1.1e-36 126.6 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Epimerase PF01370.21 KKK25499.1 - 4.1e-16 59.2 0.0 6.6e-16 58.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KKK25499.1 - 2.7e-10 40.2 0.1 5.6e-10 39.2 0.0 1.6 2 0 0 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.6 KKK25499.1 - 2.1e-08 34.3 0.2 3.2e-08 33.7 0.2 1.4 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 KKK25499.1 - 2.3e-08 33.8 0.0 5.1e-05 22.8 0.0 2.4 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KKK25499.1 - 4.2e-08 32.5 0.0 4.3e-07 29.2 0.0 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 KKK25499.1 - 7.2e-05 22.0 0.1 9.2e-05 21.7 0.1 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 KKK25499.1 - 0.00059 19.1 0.6 0.47 9.6 0.4 2.2 1 1 1 2 2 2 2 Male sterility protein Sacchrp_dh_NADP PF03435.18 KKK25499.1 - 0.0028 17.9 0.0 0.0046 17.2 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain adh_short PF00106.25 KKK25499.1 - 0.041 13.3 0.0 0.078 12.4 0.0 1.5 1 0 0 1 1 1 0 short chain dehydrogenase ADH_N PF08240.12 KKK25500.1 - 8.9e-28 96.3 1.2 1.5e-27 95.6 0.3 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KKK25500.1 - 6.2e-20 71.5 0.0 2.5e-19 69.5 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KKK25500.1 - 7.1e-06 27.1 0.0 1.6e-05 26.0 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KKK25500.1 - 9.3e-05 22.0 0.0 0.0002 20.9 0.0 1.6 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 KKK25500.1 - 0.003 16.9 0.0 0.0051 16.1 0.0 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ADH_N_assoc PF13823.6 KKK25500.1 - 0.08 12.9 0.1 0.13 12.2 0.1 1.4 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-associated Tannase PF07519.11 KKK25501.1 - 2.5e-83 280.5 0.0 3e-83 280.3 0.0 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Peptidase_S9 PF00326.21 KKK25501.1 - 0.0037 16.8 0.1 1.1 8.7 0.2 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 KKK25501.1 - 0.025 14.2 0.0 0.063 12.9 0.0 1.6 1 0 0 1 1 1 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KKK25501.1 - 0.12 11.6 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 SET PF00856.28 KKK25502.1 - 0.084 13.3 0.0 0.1 13.0 0.0 1.2 1 0 0 1 1 1 0 SET domain LAT PF15234.6 KKK25502.1 - 0.24 11.1 1.1 0.35 10.6 1.1 1.2 1 0 0 1 1 1 0 Linker for activation of T-cells p450 PF00067.22 KKK25503.1 - 1.9e-66 224.7 0.0 2.4e-66 224.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Med7 PF05983.11 KKK25504.1 - 3.1e-62 210.1 1.9 3.8e-62 209.8 1.9 1.1 1 0 0 1 1 1 1 MED7 protein MerR-DNA-bind PF09278.11 KKK25504.1 - 0.074 13.6 0.9 0.16 12.5 0.9 1.6 1 0 0 1 1 1 0 MerR, DNA binding APG6_N PF17675.1 KKK25504.1 - 0.098 13.2 2.2 0.19 12.3 2.2 1.5 1 0 0 1 1 1 0 Apg6 coiled-coil region PAP2 PF01569.21 KKK25505.1 - 4.1e-28 97.8 0.8 4.1e-28 97.8 0.8 2.1 2 0 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 KKK25505.1 - 0.0041 16.8 8.0 0.025 14.3 8.0 2.1 1 1 0 1 1 1 1 PAP2 superfamily SLATT_fungal PF18142.1 KKK25505.1 - 0.12 12.3 0.4 1 9.3 0.4 2.1 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain Colicin_V PF02674.16 KKK25505.1 - 0.2 11.6 7.0 14 5.7 3.4 3.4 3 1 0 3 3 3 0 Colicin V production protein T5orf172 PF10544.9 KKK25506.1 - 3.3e-11 43.6 0.1 2.6e-10 40.8 0.1 2.3 1 1 0 1 1 1 1 T5orf172 domain MUG113 PF13455.6 KKK25506.1 - 0.15 12.8 2.1 19 6.0 0.0 3.1 3 1 1 4 4 4 0 Meiotically up-regulated gene 113 NPC1_N PF16414.5 KKK25507.1 - 1.6e-85 286.6 4.9 2.2e-85 286.1 4.9 1.2 1 0 0 1 1 1 1 Niemann-Pick C1 N terminus Patched PF02460.18 KKK25507.1 - 7.1e-77 259.2 16.1 3.5e-76 257.0 16.1 1.7 1 1 0 1 1 1 1 Patched family Sterol-sensing PF12349.8 KKK25507.1 - 2.6e-52 176.7 7.4 2.6e-52 176.7 7.4 3.1 3 1 0 3 3 3 1 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.15 KKK25507.1 - 1.5e-06 27.4 9.8 1.5e-06 27.4 9.8 3.5 3 1 0 3 3 3 2 MMPL family REV1_C PF16727.5 KKK25507.1 - 0.019 15.4 0.0 0.047 14.1 0.0 1.7 1 0 0 1 1 1 0 DNA repair protein REV1 C-terminal domain Folate_rec PF03024.14 KKK25507.1 - 0.02 14.8 3.0 0.039 13.8 3.0 1.4 1 0 0 1 1 1 0 Folate receptor family Pkinase PF00069.25 KKK25508.1 - 2.4e-65 220.5 0.0 3.4e-65 220.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK25508.1 - 3.8e-29 101.8 0.0 6e-29 101.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KKK25508.1 - 0.014 14.4 0.0 0.027 13.4 0.0 1.5 1 1 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 KKK25508.1 - 0.042 13.2 0.1 0.082 12.3 0.1 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KKK25508.1 - 0.051 13.5 0.2 0.17 11.8 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family NeA_P2 PF12312.8 KKK25509.1 - 1.9 7.9 11.8 1.9 7.9 4.9 2.4 2 0 0 2 2 2 0 Nepovirus subgroup A polyprotein COQ9 PF08511.11 KKK25510.1 - 7e-28 96.2 0.1 1.3e-27 95.4 0.1 1.4 1 0 0 1 1 1 1 COQ9 RRM_1 PF00076.22 KKK25511.1 - 1.5e-45 152.8 0.0 4e-17 61.8 0.0 3.8 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KKK25511.1 - 3.5e-05 23.4 0.0 0.0066 16.1 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 KKK25511.1 - 0.00018 21.5 0.5 2.4 8.3 0.0 4.4 3 2 0 3 3 3 1 Limkain b1 PknH_C PF14032.6 KKK25511.1 - 0.012 15.5 3.6 12 5.6 0.2 3.2 3 0 0 3 3 3 0 PknH-like extracellular domain ATP-grasp_2 PF08442.10 KKK25511.1 - 0.015 14.9 0.0 0.12 12.0 0.0 2.2 2 0 0 2 2 2 0 ATP-grasp domain RRM_Rrp7 PF17799.1 KKK25511.1 - 0.015 15.1 0.0 7.9 6.3 0.0 2.9 3 0 0 3 3 3 0 Rrp7 RRM-like N-terminal domain RRM_3 PF08777.11 KKK25511.1 - 0.05 13.7 0.0 6.9 6.8 0.0 3.0 3 0 0 3 3 3 0 RNA binding motif RRM_occluded PF16842.5 KKK25511.1 - 0.055 13.3 0.0 15 5.5 0.0 3.1 2 1 0 2 2 2 0 Occluded RNA-recognition motif Phage_TAC_13 PF16459.5 KKK25511.1 - 0.074 13.5 0.1 89 3.6 0.0 3.2 3 0 0 3 3 3 0 Phage tail assembly chaperone, TAC PH PF00169.29 KKK25512.1 - 8.8e-07 29.4 1.2 1.1e-06 29.0 0.2 1.7 2 0 0 2 2 2 1 PH domain DUF3921 PF13060.6 KKK25512.1 - 0.047 13.7 0.2 0.12 12.4 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3921) ApoO PF09769.9 KKK25512.1 - 0.49 10.3 2.2 16 5.5 0.1 3.4 4 0 0 4 4 4 0 Apolipoprotein O Tim17 PF02466.19 KKK25513.1 - 4.2e-07 30.3 8.9 8.3e-07 29.4 8.1 1.9 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family RPT PF13446.6 KKK25514.1 - 1.5e-49 165.7 1.8 9.2e-20 70.3 0.0 4.6 4 0 0 4 4 4 4 A repeated domain in UCH-protein UCH PF00443.29 KKK25514.1 - 8e-43 146.8 0.0 1.5e-42 145.9 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KKK25514.1 - 0.0021 17.7 0.2 0.014 15.0 0.0 2.2 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase E7 PF00527.18 KKK25514.1 - 0.054 13.7 0.0 0.31 11.2 0.0 2.3 1 0 0 1 1 1 0 E7 protein, Early protein CoA_trans PF01144.23 KKK25515.1 - 7.4e-103 342.6 4.6 3.5e-61 206.4 0.8 2.0 2 0 0 2 2 2 2 Coenzyme A transferase DUF531 PF04407.12 KKK25515.1 - 0.088 12.9 0.0 0.41 10.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF531) DUF2370 PF10176.9 KKK25517.1 - 2.4e-92 308.7 0.0 3.9e-92 308.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2370) DUF2561 PF10812.8 KKK25517.1 - 0.059 13.4 0.5 0.18 11.8 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2561) WD40 PF00400.32 KKK25518.1 - 1.3e-05 25.9 0.3 0.96 10.4 0.0 3.8 3 0 0 3 3 3 2 WD domain, G-beta repeat Terpene_synth_C PF03936.16 KKK25557.1 - 0.0085 15.5 0.2 0.012 15.0 0.2 1.3 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain p450 PF00067.22 KKK25558.1 - 1.8e-52 178.7 0.0 2.6e-52 178.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Ribosomal_S18 PF01084.20 KKK25596.1 - 2e-15 56.7 0.1 3.8e-15 55.8 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S18 SAGA-Tad1 PF12767.7 KKK25597.1 - 2.7e-59 200.8 0.0 4.6e-59 200.0 0.0 1.4 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit WD40 PF00400.32 KKK25597.1 - 1.6e-22 79.4 30.3 0.0009 20.0 0.1 11.0 10 1 1 11 11 11 5 WD domain, G-beta repeat FUSC_2 PF13515.6 KKK25597.1 - 2.4e-19 69.7 17.3 6.5e-13 48.9 1.7 3.6 2 2 1 3 3 3 2 Fusaric acid resistance protein-like ANAPC4_WD40 PF12894.7 KKK25597.1 - 3.1e-14 53.0 8.2 2e-05 24.8 0.0 6.5 3 3 3 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain ALMT PF11744.8 KKK25597.1 - 8.4e-05 21.6 9.4 0.023 13.5 0.0 3.9 4 0 0 4 4 4 3 Aluminium activated malate transporter FUSC PF04632.12 KKK25597.1 - 0.0096 14.5 13.7 0.045 12.3 0.1 4.0 4 0 0 4 4 4 2 Fusaric acid resistance protein family Nup160 PF11715.8 KKK25597.1 - 0.014 14.1 0.0 0.026 13.2 0.0 1.4 1 0 0 1 1 1 0 Nucleoporin Nup120/160 FUSC-like PF12805.7 KKK25597.1 - 0.057 12.5 3.0 0.061 12.4 0.6 2.1 2 0 0 2 2 2 0 FUSC-like inner membrane protein yccS PD40 PF07676.12 KKK25597.1 - 0.077 13.0 0.2 1.5 8.9 0.0 3.2 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat ArAE_2_N PF10337.9 KKK25597.1 - 0.37 9.8 5.7 0.37 9.8 0.1 2.3 2 0 0 2 2 2 0 Putative ER transporter, 6TM, N-terminal IRF PF00605.17 KKK25597.1 - 0.4 11.0 1.4 21 5.5 0.2 2.6 2 0 0 2 2 2 0 Interferon regulatory factor transcription factor PRP1_N PF06424.12 KKK25598.1 - 3.5e-52 176.7 7.2 8.7e-52 175.5 7.2 1.7 1 0 0 1 1 1 1 PRP1 splicing factor, N-terminal TPR_19 PF14559.6 KKK25598.1 - 1.6e-25 89.4 13.8 5.5e-07 30.0 0.5 9.4 7 2 2 9 9 9 5 Tetratricopeptide repeat TPR_14 PF13428.6 KKK25598.1 - 9.1e-24 82.1 42.2 1.2e-05 25.7 0.2 13.7 7 5 8 15 15 14 8 Tetratricopeptide repeat TPR_11 PF13414.6 KKK25598.1 - 7.1e-09 35.2 7.8 0.4 10.4 0.0 7.8 6 2 2 8 8 8 2 TPR repeat TPR_16 PF13432.6 KKK25598.1 - 8.2e-09 36.0 30.5 0.0056 17.3 0.0 7.9 7 2 1 8 8 7 3 Tetratricopeptide repeat TPR_2 PF07719.17 KKK25598.1 - 1.2e-08 34.4 18.0 1 9.6 0.0 9.3 11 0 0 11 11 9 3 Tetratricopeptide repeat TPR_8 PF13181.6 KKK25598.1 - 2.3e-07 30.5 0.3 2.7 8.4 0.0 6.1 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.28 KKK25598.1 - 1.5e-06 27.8 1.7 0.34 10.8 0.0 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 KKK25598.1 - 1e-05 25.6 10.1 11 6.7 0.1 8.2 9 0 0 9 9 7 0 Tetratricopeptide repeat TPR_12 PF13424.6 KKK25598.1 - 0.003 17.8 2.3 3.4 8.0 0.0 5.9 5 1 1 6 6 6 1 Tetratricopeptide repeat DUF3808 PF10300.9 KKK25598.1 - 0.071 11.8 0.2 11 4.7 0.0 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF3808) ZNRF_3_ecto PF18212.1 KKK25598.1 - 0.074 13.1 0.3 25 4.9 0.0 4.4 6 1 0 6 6 6 0 ZNRF-3 Ectodomain TPR_21 PF09976.9 KKK25598.1 - 0.075 12.7 17.7 0.5 10.0 2.2 4.5 3 1 1 4 4 4 0 Tetratricopeptide repeat-like domain TPR_7 PF13176.6 KKK25598.1 - 0.098 12.7 0.5 40 4.5 0.0 4.6 5 0 0 5 5 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KKK25598.1 - 0.11 12.7 0.7 25 5.2 0.0 3.9 3 1 2 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 NARP1 PF12569.8 KKK25598.1 - 0.2 10.5 8.7 1.3 7.8 0.0 4.6 4 1 2 6 6 6 0 NMDA receptor-regulated protein 1 Ribosomal_60s PF00428.19 KKK25598.1 - 3.8 8.2 6.9 1.8 9.2 2.3 2.9 3 0 0 3 3 2 0 60s Acidic ribosomal protein RabGAP-TBC PF00566.18 KKK25599.1 - 2.2e-51 174.6 0.0 5.7e-51 173.2 0.0 1.7 1 1 0 1 1 1 1 Rab-GTPase-TBC domain RRM_1 PF00076.22 KKK25600.1 - 6.1e-35 118.9 0.1 2.2e-16 59.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KKK25600.1 - 2.2e-11 43.7 0.2 7.2e-05 22.8 0.0 2.8 2 1 0 2 2 2 2 RNA recognition motif RRM_3 PF08777.11 KKK25600.1 - 0.0061 16.6 0.0 1.8 8.7 0.0 2.6 2 0 0 2 2 2 2 RNA binding motif ELFV_dehydrog PF00208.21 KKK25601.1 - 2.7e-69 233.6 0.0 4.1e-69 233.0 0.0 1.3 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.12 KKK25601.1 - 1e-17 63.1 0.0 2.7e-13 48.5 0.0 2.2 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.18 KKK25601.1 - 0.0026 17.7 0.0 0.024 14.5 0.0 2.2 2 0 0 2 2 2 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain Ish1 PF10281.9 KKK25601.1 - 0.088 13.1 0.0 0.24 11.7 0.0 1.8 1 0 0 1 1 1 0 Putative stress-responsive nuclear envelope protein PPR_2 PF13041.6 KKK25602.1 - 1.2e-05 25.4 0.2 0.32 11.2 0.0 4.5 5 0 0 5 5 5 2 PPR repeat family TPR_14 PF13428.6 KKK25602.1 - 0.00033 21.2 0.1 41 5.4 0.0 5.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 KKK25602.1 - 0.0029 18.1 1.4 1.2 9.7 0.4 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat PPR PF01535.20 KKK25602.1 - 0.018 15.3 7.3 1.5 9.2 0.1 5.7 7 0 0 7 7 7 0 PPR repeat UQ_con PF00179.26 KKK25614.1 - 9.2e-28 96.6 0.1 4.1e-15 55.6 0.0 3.1 2 1 0 2 2 2 2 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KKK25614.1 - 9.6e-05 22.1 0.1 0.36 10.5 0.0 3.0 3 1 0 3 3 3 2 Prokaryotic E2 family B RhoGAP PF00620.27 KKK25615.1 - 4.2e-37 127.3 0.5 8.6e-37 126.3 0.5 1.5 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.22 KKK25615.1 - 7e-29 99.8 35.1 1.8e-11 44.0 5.3 4.7 5 0 0 5 5 5 4 LIM domain zf_C2H2_13 PF18508.1 KKK25615.1 - 0.17 11.5 1.8 0.29 10.8 0.1 2.3 2 0 0 2 2 2 0 Zinc finger domain Desulfoferrod_N PF06397.12 KKK25615.1 - 0.17 11.5 2.8 0.14 11.8 0.4 2.2 2 0 0 2 2 2 0 Desulfoferrodoxin, N-terminal domain 3Beta_HSD PF01073.19 KKK25616.1 - 1.8e-41 142.0 0.7 1.3e-24 86.7 0.0 2.9 2 1 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KKK25616.1 - 1e-15 57.8 0.1 1.2e-09 38.1 0.0 2.8 2 1 0 2 2 2 2 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KKK25616.1 - 4e-08 33.0 0.0 0.00036 20.0 0.0 3.7 4 0 0 4 4 4 2 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 KKK25616.1 - 2.7e-07 30.0 0.0 0.00018 20.7 0.0 2.5 2 1 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.17 KKK25616.1 - 4.7e-05 22.6 0.0 0.013 14.6 0.0 2.8 2 1 0 2 2 2 2 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 KKK25616.1 - 0.011 14.9 0.0 0.14 11.2 0.0 2.0 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Pkinase PF00069.25 KKK25617.1 - 1.8e-58 198.0 0.0 1.7e-38 132.5 0.1 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KKK25617.1 - 3.4e-26 92.1 0.0 2.9e-20 72.7 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.24 KKK25617.1 - 3.5e-12 46.5 0.0 8.5e-12 45.2 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain Kinase-like PF14531.6 KKK25617.1 - 3.2e-08 33.2 0.5 1.9e-05 24.2 0.0 2.7 3 0 0 3 3 3 2 Kinase-like APH PF01636.23 KKK25617.1 - 4.5e-05 23.5 0.0 0.0033 17.4 0.2 2.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KKK25617.1 - 0.0035 16.7 0.0 0.0067 15.8 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KKK25617.1 - 0.0087 15.0 0.1 0.017 14.1 0.1 1.4 1 0 0 1 1 1 1 Haspin like kinase domain PAS PF00989.25 KKK25617.1 - 0.0099 15.9 0.0 0.027 14.4 0.0 1.8 1 0 0 1 1 1 1 PAS fold FTA2 PF13095.6 KKK25617.1 - 0.022 14.4 0.0 7.4 6.1 0.0 2.5 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 PAS_4 PF08448.10 KKK25617.1 - 0.065 13.5 0.0 0.21 11.8 0.0 1.9 1 0 0 1 1 1 0 PAS fold Seadorna_VP7 PF07387.11 KKK25617.1 - 0.065 12.3 0.1 0.18 10.8 0.1 1.7 2 0 0 2 2 2 0 Seadornavirus VP7 PAS_9 PF13426.7 KKK25617.1 - 0.1 12.9 0.0 0.29 11.4 0.0 1.7 1 0 0 1 1 1 0 PAS domain Pkinase_C PF00433.24 KKK25617.1 - 3.7 8.3 6.5 7.4 7.4 2.8 3.3 2 1 0 2 2 2 0 Protein kinase C terminal domain Malic_M PF03949.15 KKK25625.1 - 1.1e-89 300.1 0.0 1.6e-89 299.6 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 KKK25625.1 - 3.6e-64 215.9 0.2 8.4e-64 214.7 0.0 1.7 2 0 0 2 2 2 1 Malic enzyme, N-terminal domain Esterase PF00756.20 KKK25626.1 - 6.4e-10 39.1 0.0 2.5e-09 37.2 0.0 1.7 1 1 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.8 KKK25626.1 - 0.00016 21.1 0.0 0.0002 20.7 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KKK25626.1 - 0.00053 20.7 0.1 0.00066 20.4 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KKK25626.1 - 0.002 17.6 0.0 0.0033 16.9 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family MFS_1 PF07690.16 KKK25629.1 - 7.3e-16 58.0 44.4 3e-09 36.3 29.5 2.4 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KKK25629.1 - 0.00016 20.7 1.8 0.00016 20.7 1.8 2.6 3 0 0 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.13 KKK25629.1 - 0.014 13.8 16.2 0.024 13.1 0.2 3.9 2 1 1 3 3 3 0 Fungal trichothecene efflux pump (TRI12) UPF0154 PF03672.13 KKK25629.1 - 0.15 12.1 0.0 0.68 10.0 0.0 2.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0154) MFS_1 PF07690.16 KKK25630.1 - 2e-10 40.1 44.0 3e-05 23.1 33.9 3.8 2 1 1 3 3 3 2 Major Facilitator Superfamily OATP PF03137.20 KKK25630.1 - 0.044 12.1 12.5 0.69 8.1 1.0 2.9 1 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Cytomega_TRL10 PF06084.11 KKK25630.1 - 0.27 11.2 3.7 0.55 10.2 0.8 2.4 2 0 0 2 2 2 0 Cytomegalovirus TRL10 protein Pox_A14 PF05767.12 KKK25630.1 - 9.2 6.5 6.6 1.2 9.4 0.4 2.7 4 0 0 4 4 4 0 Poxvirus virion envelope protein A14 SnoaL_2 PF12680.7 KKK25631.1 - 1.8e-11 44.6 1.1 2.2e-11 44.3 1.1 1.1 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_4 PF13577.6 KKK25631.1 - 7.3e-09 35.8 0.3 9e-09 35.5 0.3 1.2 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_3 PF13474.6 KKK25631.1 - 5.1e-06 26.7 0.2 6.5e-06 26.4 0.2 1.1 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 KKK25631.1 - 6.1e-05 23.4 0.5 9.2e-05 22.8 0.5 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4440) LEH PF07858.12 KKK25631.1 - 0.00022 21.3 0.2 0.00026 21.1 0.2 1.1 1 0 0 1 1 1 1 Limonene-1,2-epoxide hydrolase catalytic domain NTF2 PF02136.20 KKK25631.1 - 0.0034 17.9 0.1 0.0044 17.6 0.1 1.2 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain HYR PF02494.16 KKK25631.1 - 0.07 13.5 1.1 2.8 8.3 0.1 2.4 2 1 0 2 2 2 0 HYR domain ZipA_C PF04354.13 KKK25631.1 - 0.12 12.2 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 ZipA, C-terminal FtsZ-binding domain BAMBI PF06211.12 KKK25631.1 - 0.19 12.0 0.0 0.39 11.0 0.0 1.5 1 1 1 2 2 2 0 BMP and activin membrane-bound inhibitor (BAMBI) N-terminal domain E1-E2_ATPase PF00122.20 KKK25632.1 - 1.6e-39 135.3 1.3 6.6e-39 133.3 0.9 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 KKK25632.1 - 8.2e-37 126.7 3.0 8.2e-37 126.7 3.0 2.7 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KKK25632.1 - 8.1e-23 81.8 0.1 1.8e-10 41.5 0.0 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KKK25632.1 - 4.9e-17 61.8 0.0 9e-17 60.9 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KKK25632.1 - 8.6e-10 38.2 0.0 2.2e-09 36.9 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus DUF2157 PF09925.9 KKK25632.1 - 1.4e-05 24.9 6.4 0.00075 19.3 0.0 3.4 4 0 0 4 4 4 2 Predicted membrane protein (DUF2157) Hydrolase_3 PF08282.12 KKK25632.1 - 4.1e-05 23.4 0.2 7.9e-05 22.5 0.2 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Sigma_reg_N PF13800.6 KKK25632.1 - 0.079 13.2 1.1 0.38 11.1 1.1 2.1 1 0 0 1 1 1 0 Sigma factor regulator N-terminal TMEM43 PF07787.12 KKK25632.1 - 0.19 11.1 1.4 3.5 6.9 0.3 2.4 2 0 0 2 2 2 0 Transmembrane protein 43 DUF3262 PF11660.8 KKK25632.1 - 0.45 10.9 6.5 9.5 6.7 0.1 3.1 3 0 0 3 3 2 0 Protein of unknown function (DUF3262) DUF1218 PF06749.12 KKK25632.1 - 5.4 7.6 7.5 0.66 10.5 0.2 3.0 3 0 0 3 3 2 0 Protein of unknown function (DUF1218) MFS_1 PF07690.16 KKK25633.1 - 2.8e-40 138.3 33.6 4.5e-40 137.7 33.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KKK25633.1 - 3.2e-14 52.6 5.6 3.2e-14 52.6 5.6 1.5 2 0 0 2 2 2 1 Sugar (and other) transporter Zn_clus PF00172.18 KKK25633.1 - 3.8e-06 26.9 10.6 8.2e-06 25.9 10.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_3 PF05977.13 KKK25633.1 - 0.025 13.0 0.6 0.041 12.3 0.6 1.2 1 0 0 1 1 1 0 Transmembrane secretion effector MARVEL PF01284.23 KKK25646.1 - 4.3e-19 69.0 12.8 5.2e-19 68.7 12.8 1.1 1 0 0 1 1 1 1 Membrane-associating domain CTP_transf_1 PF01148.20 KKK25646.1 - 0.2 11.4 6.1 0.23 11.2 6.1 1.1 1 0 0 1 1 1 0 Cytidylyltransferase family Actin PF00022.19 KKK25647.1 - 9.1e-52 176.0 0.0 5.8e-28 97.6 0.0 2.5 2 1 0 2 2 2 2 Actin Tubulin_2 PF13809.6 KKK25647.1 - 0.2 10.8 2.2 0.42 9.7 2.2 1.5 1 0 0 1 1 1 0 Tubulin like DASH_Dad4 PF08650.10 KKK25648.1 - 6.1e-31 106.2 8.2 7.5e-31 105.9 8.2 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad4 CD34_antigen PF06365.12 KKK25648.1 - 0.011 15.3 1.0 0.013 15.1 1.0 1.1 1 0 0 1 1 1 0 CD34/Podocalyxin family GM_CSF PF01109.17 KKK25648.1 - 0.071 13.3 0.4 0.092 12.9 0.4 1.2 1 0 0 1 1 1 0 Granulocyte-macrophage colony-stimulating factor HOK_GEF PF01848.16 KKK25648.1 - 0.099 12.1 0.1 0.15 11.5 0.1 1.3 1 0 0 1 1 1 0 Hok/gef family YL1_C PF08265.11 KKK25649.1 - 4.4e-16 58.3 0.4 7.2e-16 57.6 0.4 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain Got1 PF04178.12 KKK25650.1 - 3.5e-14 53.2 13.8 4.4e-14 52.9 13.8 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family SdpI PF13630.6 KKK25650.1 - 0.76 10.0 8.0 2.9 8.1 1.6 2.4 2 0 0 2 2 2 0 SdpI/YhfL protein family DUF373 PF04123.13 KKK25650.1 - 0.85 9.0 5.5 0.33 10.3 3.0 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF373) Profilin PF00235.19 KKK25651.1 - 1.7e-38 131.7 0.2 1.9e-38 131.6 0.2 1.0 1 0 0 1 1 1 1 Profilin Sec63 PF02889.16 KKK25653.1 - 1.9e-133 443.4 0.0 1.2e-81 273.7 0.1 2.3 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 KKK25653.1 - 1.1e-50 171.8 1.2 1.7e-25 89.8 0.8 3.2 4 0 0 4 4 4 2 DEAD/DEAH box helicase ResIII PF04851.15 KKK25653.1 - 1.1e-22 80.9 0.0 3.5e-11 43.4 0.0 2.5 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KKK25653.1 - 2.7e-17 63.1 0.0 9.2e-07 29.2 0.0 4.3 4 2 0 4 4 4 2 Helicase conserved C-terminal domain AAA_22 PF13401.6 KKK25653.1 - 1e-07 32.3 0.3 0.0018 18.6 0.0 3.6 2 1 0 2 2 2 2 AAA domain AAA_30 PF13604.6 KKK25653.1 - 2.8e-07 30.5 0.3 0.007 16.1 0.5 2.4 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 KKK25653.1 - 1.4e-05 25.4 0.6 0.0037 17.6 0.7 2.7 2 0 0 2 2 2 1 AAA domain Helicase_PWI PF18149.1 KKK25653.1 - 0.013 15.7 0.0 0.035 14.3 0.0 1.7 1 0 0 1 1 1 0 N-terminal helicase PWI domain TniB PF05621.11 KKK25653.1 - 0.028 13.9 0.5 16 4.9 0.0 3.4 4 0 0 4 4 4 0 Bacterial TniB protein IstB_IS21 PF01695.17 KKK25653.1 - 0.095 12.4 0.4 8.4 6.1 0.0 3.4 4 0 0 4 4 4 0 IstB-like ATP binding protein DUF3431 PF11913.8 KKK25654.1 - 4.2e-85 284.9 1.0 5.1e-85 284.6 1.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) Ras PF00071.22 KKK25655.1 - 1.6e-39 135.1 0.0 1.7e-38 131.8 0.0 2.0 1 1 0 1 1 1 1 Ras family Roc PF08477.13 KKK25655.1 - 5.5e-30 104.1 0.0 7.8e-30 103.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKK25655.1 - 3.5e-11 42.9 0.0 5.7e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KKK25655.1 - 0.00023 21.2 0.0 0.00034 20.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KKK25655.1 - 0.0011 19.4 0.0 0.0016 18.8 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain SRPRB PF09439.10 KKK25655.1 - 0.0096 15.4 0.0 0.015 14.8 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 KKK25655.1 - 0.012 15.8 0.0 0.037 14.3 0.0 1.7 2 1 0 2 2 2 0 AAA domain Gtr1_RagA PF04670.12 KKK25655.1 - 0.019 14.3 0.0 0.025 13.9 0.0 1.1 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 KKK25655.1 - 0.05 13.4 0.0 0.29 10.9 0.0 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_7 PF12775.7 KKK25655.1 - 0.051 13.1 0.1 0.079 12.5 0.1 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_14 PF13173.6 KKK25655.1 - 0.07 13.2 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KKK25655.1 - 0.072 13.0 0.0 0.15 12.0 0.0 1.5 2 0 0 2 2 2 0 RsgA GTPase ATP_bind_1 PF03029.17 KKK25655.1 - 0.084 12.6 0.2 12 5.5 0.1 2.6 2 1 1 3 3 3 0 Conserved hypothetical ATP binding protein AAA_24 PF13479.6 KKK25655.1 - 0.1 12.3 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KKK25655.1 - 0.13 12.5 0.3 0.21 11.8 0.0 1.5 2 0 0 2 2 1 0 AAA domain AAA_5 PF07728.14 KKK25655.1 - 0.19 11.8 0.0 0.3 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NACHT PF05729.12 KKK25655.1 - 0.2 11.6 0.1 0.3 11.0 0.1 1.3 1 0 0 1 1 1 0 NACHT domain Metallophos PF00149.28 KKK25656.1 - 9.8e-10 39.3 0.0 2.1e-09 38.2 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KKK25656.1 - 6.5e-07 29.7 0.0 1.6e-05 25.2 0.0 2.3 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain Sugar_tr PF00083.24 KKK25657.1 - 2.9e-107 359.4 22.5 3.3e-107 359.1 22.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKK25657.1 - 5.9e-26 91.2 34.8 3.7e-18 65.6 8.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KKK25657.1 - 0.00013 20.7 3.3 0.00013 20.7 3.3 3.3 2 2 1 3 3 3 2 MFS/sugar transport protein MFS_3 PF05977.13 KKK25657.1 - 0.0089 14.5 0.1 0.0089 14.5 0.1 1.9 2 0 0 2 2 2 1 Transmembrane secretion effector YebO PF13974.6 KKK25657.1 - 6.4 6.9 5.9 28 4.9 1.0 2.6 2 0 0 2 2 2 0 YebO-like protein DUF3792 PF12670.7 KKK25657.1 - 10 6.4 20.7 14 5.9 6.8 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF3792) adh_short PF00106.25 KKK25658.1 - 4.3e-12 45.9 0.0 1.4e-06 27.9 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KKK25658.1 - 2.7e-07 30.4 0.0 0.00027 20.6 0.0 2.0 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase ADH_N PF08240.12 KKK25659.1 - 7.7e-22 77.2 2.0 7.7e-22 77.2 2.0 1.6 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KKK25659.1 - 0.00049 20.1 0.1 0.99 9.4 0.0 2.8 3 0 0 3 3 3 2 Zinc-binding dehydrogenase ADH_N_assoc PF13823.6 KKK25659.1 - 0.037 14.0 0.0 0.07 13.1 0.0 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-associated Abhydrolase_1 PF00561.20 KKK25660.1 - 4e-11 43.1 0.0 2.1e-08 34.1 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KKK25660.1 - 9.1e-07 29.7 0.0 1.1e-06 29.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KKK25660.1 - 9.9e-07 28.3 0.0 1.1e-05 24.8 0.0 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 KKK25660.1 - 6.5e-05 21.8 0.0 0.00015 20.5 0.0 1.6 1 1 0 1 1 1 1 Ndr family Ribonuclease_3 PF00636.26 KKK25661.1 - 0.00049 20.7 0.0 0.0033 18.0 0.0 2.0 1 1 0 1 1 1 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 KKK25661.1 - 0.0091 16.2 0.0 0.013 15.7 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease-III-like 2OG-FeII_Oxy PF03171.20 KKK25664.1 - 3.2e-17 62.9 0.0 7.8e-17 61.6 0.0 1.4 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 KKK25664.1 - 1.9e-12 48.0 0.0 6.1e-12 46.3 0.0 1.9 1 1 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal AflR PF08493.10 KKK25665.1 - 1.1e-15 57.9 12.1 1.6e-15 57.3 12.1 1.2 1 0 0 1 1 1 1 Aflatoxin regulatory protein Zn_clus PF00172.18 KKK25665.1 - 3.9e-09 36.5 11.1 6.5e-09 35.8 11.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Spem1 PF15670.5 KKK25665.1 - 0.044 13.4 2.1 0.061 12.9 2.1 1.2 1 0 0 1 1 1 0 Spermatid maturation protein 1 2OG-FeII_Oxy_2 PF13532.6 KKK25666.1 - 8.8e-36 123.9 0.1 1.2e-35 123.4 0.1 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily zf-GRF PF06839.12 KKK25666.1 - 1.6e-06 28.1 5.7 2.8e-06 27.3 5.7 1.4 1 0 0 1 1 1 1 GRF zinc finger DUF3425 PF11905.8 KKK25667.1 - 1.6e-22 79.8 0.9 2.8e-22 79.0 0.9 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) SlyX PF04102.12 KKK25667.1 - 0.0026 18.3 1.1 0.0063 17.1 1.1 1.7 1 0 0 1 1 1 1 SlyX NPV_P10 PF05531.12 KKK25667.1 - 0.0037 17.7 1.1 0.0072 16.8 1.1 1.4 1 0 0 1 1 1 1 Nucleopolyhedrovirus P10 protein CALCOCO1 PF07888.11 KKK25667.1 - 0.013 14.4 7.9 0.017 14.0 7.9 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Exonuc_VII_L PF02601.15 KKK25667.1 - 0.021 14.4 5.1 0.032 13.8 5.1 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit BLOC1_2 PF10046.9 KKK25667.1 - 0.066 13.5 2.3 0.11 12.8 2.3 1.3 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Fmp27_WPPW PF10359.9 KKK25667.1 - 0.099 11.5 5.0 0.15 10.9 5.0 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DUF1465 PF07323.12 KKK25667.1 - 0.1 12.4 5.1 0.16 11.8 5.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1465) Macoilin PF09726.9 KKK25667.1 - 0.12 10.9 6.1 0.17 10.4 6.1 1.1 1 0 0 1 1 1 0 Macoilin family Jnk-SapK_ap_N PF09744.9 KKK25667.1 - 0.13 12.5 7.6 0.2 11.9 7.6 1.2 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Fib_alpha PF08702.10 KKK25667.1 - 0.14 12.4 4.7 0.27 11.4 4.7 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family LCD1 PF09798.9 KKK25667.1 - 0.14 10.7 3.1 0.2 10.1 3.1 1.2 1 0 0 1 1 1 0 DNA damage checkpoint protein DUF3573 PF12097.8 KKK25667.1 - 0.27 10.0 0.3 0.35 9.6 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) End3 PF12761.7 KKK25667.1 - 0.34 11.0 7.7 0.49 10.5 7.7 1.2 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 V_ATPase_I PF01496.19 KKK25667.1 - 0.43 8.4 1.8 0.55 8.1 1.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family MbeD_MobD PF04899.12 KKK25667.1 - 0.48 10.6 5.7 0.61 10.2 3.8 2.1 2 0 0 2 2 2 0 MbeD/MobD like FlaC_arch PF05377.11 KKK25667.1 - 0.54 10.7 2.2 1.1 9.7 2.2 1.4 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) Holin_BhlA PF10960.8 KKK25667.1 - 0.55 10.2 3.1 1.4 9.0 3.1 1.6 1 0 0 1 1 1 0 BhlA holin family DUF1664 PF07889.12 KKK25667.1 - 0.6 10.2 3.2 1 9.4 3.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Prominin PF05478.11 KKK25667.1 - 1.1 7.2 3.6 1.5 6.7 3.6 1.1 1 0 0 1 1 1 0 Prominin DUF4407 PF14362.6 KKK25667.1 - 1.5 8.1 4.6 2.2 7.5 4.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF641 PF04859.12 KKK25667.1 - 1.7 9.0 7.6 2.7 8.3 7.6 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) Phlebovirus_NSM PF07246.11 KKK25667.1 - 2 7.7 5.7 2.9 7.2 5.7 1.1 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M Fringe PF02434.16 KKK25668.1 - 5.3e-10 39.2 0.1 8.1e-09 35.3 0.1 2.2 1 1 0 1 1 1 1 Fringe-like PAN_1 PF00024.26 KKK25668.1 - 0.0045 16.9 0.1 0.0082 16.1 0.1 1.4 1 0 0 1 1 1 1 PAN domain PAN_2 PF08276.11 KKK25668.1 - 0.0045 17.1 0.1 0.0087 16.2 0.1 1.5 1 0 0 1 1 1 1 PAN-like domain PAN_4 PF14295.6 KKK25668.1 - 0.038 13.9 0.6 0.12 12.3 0.6 1.8 1 0 0 1 1 1 0 PAN domain Glyco_transf_34 PF05637.12 KKK25668.1 - 0.64 9.7 2.8 1.1 8.9 2.8 1.3 1 0 0 1 1 1 0 galactosyl transferase GMA12/MNN10 family M20_dimer PF07687.14 KKK25669.1 - 3.9e-09 36.4 0.1 1.1e-08 35.0 0.0 1.7 2 0 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M20 PF01546.28 KKK25669.1 - 1.7e-08 34.5 0.2 3e-08 33.6 0.2 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 PhyH PF05721.13 KKK25670.1 - 1.1e-11 45.5 0.0 1.7e-11 44.8 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.12 KKK25670.1 - 9.4e-09 34.5 0.1 0.017 13.9 0.0 3.0 3 0 0 3 3 3 3 Protein of unknown function (DUF1479) DPRP PF04244.13 KKK25670.1 - 0.085 12.7 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 Deoxyribodipyrimidine photo-lyase-related protein MFS_1 PF07690.16 KKK25671.1 - 7e-29 100.9 37.0 7e-29 100.9 37.0 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily bZIP_1 PF00170.21 KKK25672.1 - 5.3e-10 39.2 15.9 8.9e-10 38.5 15.9 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KKK25672.1 - 2e-06 27.7 12.2 4e-06 26.8 12.2 1.5 1 0 0 1 1 1 1 Basic region leucine zipper FPP PF05911.11 KKK25672.1 - 0.0012 17.2 4.7 0.0013 17.0 4.7 1.1 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil bZIP_Maf PF03131.17 KKK25672.1 - 0.016 15.7 10.6 0.031 14.8 10.6 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor DivIC PF04977.15 KKK25672.1 - 0.14 12.0 4.2 0.3 10.9 4.2 1.5 1 0 0 1 1 1 0 Septum formation initiator SR-25 PF10500.9 KKK25672.1 - 0.28 10.7 10.7 0.41 10.2 10.7 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein LCD1 PF09798.9 KKK25672.1 - 0.38 9.2 4.1 0.49 8.9 4.1 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein FapA PF03961.13 KKK25672.1 - 0.56 8.7 3.1 0.74 8.3 3.1 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Occludin_ELL PF07303.13 KKK25672.1 - 1.2 9.8 7.7 2.3 9.0 7.7 1.3 1 0 0 1 1 1 0 Occludin homology domain Hemerythrin PF01814.23 KKK25673.1 - 0.00036 21.2 0.0 0.87 10.2 0.0 2.3 1 1 1 2 2 2 2 Hemerythrin HHE cation binding domain DUF3328 PF11807.8 KKK25674.1 - 6.7e-58 196.1 0.2 7.9e-58 195.8 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF4188 PF13826.6 KKK25675.1 - 7.8e-32 110.1 0.3 1e-31 109.7 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4188) Dabb PF07876.12 KKK25675.1 - 0.0027 18.3 0.0 0.0043 17.6 0.0 1.2 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain ANF_receptor PF01094.28 KKK25675.1 - 0.037 13.1 0.0 0.053 12.6 0.0 1.2 1 0 0 1 1 1 0 Receptor family ligand binding region HSP70 PF00012.20 KKK25676.1 - 6.2e-77 259.2 0.0 2.4e-76 257.2 0.0 1.7 1 1 0 1 1 1 1 Hsp70 protein Arginase PF00491.21 KKK25678.1 - 9.7e-09 35.1 0.0 1.1e-08 34.9 0.0 1.1 1 0 0 1 1 1 1 Arginase family MFS_1 PF07690.16 KKK25679.1 - 5.7e-29 101.1 19.6 5.7e-29 101.1 19.6 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Peptidase_A8 PF01252.18 KKK25679.1 - 1.5 9.0 8.3 1.3 9.2 1.8 3.1 3 1 0 3 3 3 0 Signal peptidase (SPase) II PAP_assoc PF03828.19 KKK25683.1 - 7e-17 61.4 0.1 1.6e-16 60.3 0.1 1.6 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 KKK25683.1 - 3.6e-06 27.2 0.0 7.7e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 KKK25683.1 - 0.11 12.5 0.0 0.24 11.5 0.0 1.4 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase Ras PF00071.22 KKK25700.1 - 1.4e-53 180.8 0.0 1.6e-53 180.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KKK25700.1 - 3.5e-22 78.9 0.0 4.8e-22 78.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKK25700.1 - 1.2e-06 28.1 0.0 1.7e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KKK25700.1 - 0.0048 16.3 0.0 0.0067 15.9 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 KKK25700.1 - 0.035 13.5 0.0 0.042 13.2 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region NB-ARC PF00931.22 KKK25700.1 - 0.036 13.3 0.1 0.37 9.9 0.0 2.0 1 1 1 2 2 2 0 NB-ARC domain Selenoprotein_S PF06936.11 KKK25703.1 - 2.8 7.7 8.8 0.041 13.7 0.8 2.0 2 1 0 2 2 2 0 Selenoprotein S (SelS) Myosin_head PF00063.21 KKK25704.1 - 3.1e-272 904.8 0.2 7.7e-272 903.5 0.2 1.7 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_N PF02736.19 KKK25704.1 - 4.5e-10 39.2 0.0 1.3e-09 37.7 0.0 1.9 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain Myosin_tail_1 PF01576.19 KKK25704.1 - 1e-09 36.9 201.0 1e-09 36.9 201.0 5.3 1 1 1 2 2 2 1 Myosin tail GAS PF13851.6 KKK25704.1 - 0.00051 19.5 29.3 0.00051 19.5 29.3 14.5 2 2 13 17 17 17 2 Growth-arrest specific micro-tubule binding Muted PF14942.6 KKK25704.1 - 0.0013 19.1 12.0 0.0013 19.1 12.0 14.5 3 2 12 16 16 16 1 Organelle biogenesis, Muted-like protein AAA_22 PF13401.6 KKK25704.1 - 0.11 12.8 0.0 0.11 12.8 0.0 4.5 4 0 0 4 4 4 0 AAA domain zf-C3H1 PF10650.9 KKK25705.1 - 2.5e-12 46.3 3.4 4.5e-12 45.5 3.4 1.5 1 0 0 1 1 1 1 Putative zinc-finger domain APG6_N PF17675.1 KKK25705.1 - 0.0059 17.1 5.2 0.0059 17.1 5.2 3.3 3 0 0 3 3 3 1 Apg6 coiled-coil region Ribosomal_S19e PF01090.19 KKK25705.1 - 0.35 10.6 2.4 0.89 9.3 2.4 1.6 1 0 0 1 1 1 0 Ribosomal protein S19e SPT16 PF08644.11 KKK25705.1 - 4.3 7.5 6.0 1 9.5 0.6 2.4 2 0 0 2 2 2 0 FACT complex subunit (SPT16/CDC68) DHHC PF01529.20 KKK25706.1 - 2.4e-07 30.9 3.3 3.4e-07 30.4 3.3 1.2 1 0 0 1 1 1 1 DHHC palmitoyltransferase MpPF26 PF07666.11 KKK25706.1 - 0.45 10.6 2.9 0.69 10.0 2.9 1.2 1 0 0 1 1 1 0 M penetrans paralogue family 26 Sugar_tr PF00083.24 KKK25723.1 - 2.5e-78 264.0 14.6 3.1e-78 263.7 14.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKK25723.1 - 5.4e-17 61.7 25.0 5.4e-17 61.7 25.0 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily SK_channel PF03530.14 KKK25723.1 - 0.14 12.2 0.0 0.51 10.3 0.0 1.9 2 0 0 2 2 2 0 Calcium-activated SK potassium channel DUF2456 PF10445.9 KKK25723.1 - 0.8 9.8 3.5 3.1 7.9 0.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2456) Zn_clus PF00172.18 KKK25724.1 - 1.5e-08 34.6 13.3 3e-08 33.7 13.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KKK25724.1 - 3.4e-08 32.8 0.4 2.4e-07 30.1 0.0 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain ABC2_membrane PF01061.24 KKK25725.1 - 4.5e-82 274.5 50.5 2.5e-46 157.7 19.4 2.6 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 KKK25725.1 - 2.5e-40 138.2 0.0 4.8e-19 69.2 0.0 2.8 3 0 0 3 3 2 2 ABC transporter PDR_CDR PF06422.12 KKK25725.1 - 1.8e-21 75.9 0.1 1.8e-21 75.9 0.1 4.2 5 0 0 5 5 5 2 CDR ABC transporter ABC2_membrane_3 PF12698.7 KKK25725.1 - 8.6e-11 41.5 29.2 7.8e-09 35.1 11.9 2.7 3 1 0 3 3 3 2 ABC-2 family transporter protein AAA_16 PF13191.6 KKK25725.1 - 5.8e-06 26.8 0.0 0.0021 18.4 0.1 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 KKK25725.1 - 0.00014 22.4 0.0 0.0065 17.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 KKK25725.1 - 0.00038 20.4 0.0 0.11 12.3 0.0 2.9 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 KKK25725.1 - 0.0012 19.1 0.0 0.039 14.2 0.0 3.1 3 1 0 3 3 3 1 AAA domain RsgA_GTPase PF03193.16 KKK25725.1 - 0.0014 18.5 0.0 0.0089 15.9 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 KKK25725.1 - 0.0051 16.5 0.0 0.12 12.2 0.0 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain SMC_N PF02463.19 KKK25725.1 - 0.0066 15.9 0.0 4.2 6.7 0.0 3.0 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_28 PF13521.6 KKK25725.1 - 0.021 15.0 0.1 0.079 13.2 0.1 2.0 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 KKK25725.1 - 0.022 14.8 0.0 6.6 6.9 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_33 PF13671.6 KKK25725.1 - 0.022 14.9 0.0 0.23 11.6 0.0 2.6 3 0 0 3 3 3 0 AAA domain DnaB_C PF03796.15 KKK25725.1 - 0.062 12.6 0.0 5.2 6.3 0.0 2.2 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain NACHT PF05729.12 KKK25725.1 - 0.092 12.7 0.3 2.9 7.8 0.1 2.9 3 0 0 3 3 3 0 NACHT domain AAA_30 PF13604.6 KKK25725.1 - 0.15 11.7 0.0 2.1 8.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF4646 PF15496.6 KKK25726.1 - 2.2e-09 38.0 0.0 2.2e-08 34.8 0.0 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF4646) DUF2062 PF09835.9 KKK25726.1 - 0.13 12.1 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) Response_reg PF00072.24 KKK25727.1 - 2.2e-21 76.1 0.3 5.4e-21 74.9 0.1 1.8 2 0 0 2 2 2 1 Response regulator receiver domain HATPase_c PF02518.26 KKK25727.1 - 4.1e-19 69.2 0.1 9.3e-19 68.0 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 KKK25727.1 - 4.9e-12 45.7 0.3 1.3e-11 44.3 0.3 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Phosphodiest PF01663.22 KKK25729.1 - 2.9e-15 56.7 0.1 5.2e-15 55.9 0.1 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 KKK25729.1 - 3.3e-05 23.4 0.1 6.4e-05 22.4 0.1 1.4 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.23 KKK25729.1 - 0.00022 20.7 0.1 0.00038 19.9 0.1 1.4 1 0 0 1 1 1 1 Sulfatase PglZ PF08665.12 KKK25729.1 - 0.071 13.2 0.4 14 5.7 0.1 2.3 2 0 0 2 2 2 0 PglZ domain Gly-zipper_YMGG PF13441.6 KKK25729.1 - 0.58 9.9 4.6 1.3 8.8 4.6 1.5 1 0 0 1 1 1 0 YMGG-like Gly-zipper DUF4083 PF13314.6 KKK25730.1 - 0.018 15.0 0.7 0.029 14.3 0.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) DUF5326 PF17260.2 KKK25730.1 - 0.041 14.0 0.4 0.071 13.3 0.4 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5326) DUF3377 PF11857.8 KKK25730.1 - 0.11 12.4 0.4 0.44 10.5 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) DUF3384 PF11864.8 KKK25731.1 - 1.3e-99 334.3 2.3 1.3e-99 334.3 2.3 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3384) Rap_GAP PF02145.15 KKK25731.1 - 8e-51 172.2 0.0 1.4e-50 171.4 0.0 1.4 1 0 0 1 1 1 1 Rap/ran-GAP Tuberin PF03542.16 KKK25731.1 - 1.9e-37 129.2 0.0 2.1e-32 112.6 0.0 3.2 3 0 0 3 3 3 2 Tuberin RTP1_C1 PF10363.9 KKK25731.1 - 0.006 16.7 0.0 0.57 10.4 0.0 3.3 3 0 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 SPT_ssu-like PF11779.8 KKK25732.1 - 8.8e-26 89.3 2.7 1.7e-25 88.4 2.7 1.5 1 0 0 1 1 1 1 Small subunit of serine palmitoyltransferase-like RF-1 PF00472.20 KKK25733.1 - 3.6e-24 84.9 4.4 4.9e-24 84.5 4.4 1.2 1 0 0 1 1 1 1 RF-1 domain ECH_1 PF00378.20 KKK25734.1 - 1.7e-26 93.1 0.0 2.3e-26 92.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KKK25734.1 - 3.5e-20 72.8 0.0 4e-20 72.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Pet100 PF09803.9 KKK25735.1 - 1.1e-18 67.5 0.1 1.4e-18 67.2 0.1 1.1 1 0 0 1 1 1 1 Pet100 Vps51 PF08700.11 KKK25736.1 - 1.7e-15 56.9 0.0 2.1e-14 53.3 0.0 2.8 2 0 0 2 2 2 1 Vps51/Vps67 Vps53_N PF04100.12 KKK25736.1 - 0.0011 18.1 0.0 0.0039 16.2 0.1 1.9 2 0 0 2 2 2 1 Vps53-like, N-terminal Apolipoprotein PF01442.18 KKK25736.1 - 0.023 14.6 8.5 2.3 8.1 0.1 3.8 3 1 0 3 3 3 0 Apolipoprotein A1/A4/E domain GlutR_dimer PF00745.20 KKK25736.1 - 0.26 11.8 1.6 13 6.3 0.1 3.8 4 0 0 4 4 4 0 Glutamyl-tRNAGlu reductase, dimerisation domain DUF883 PF05957.13 KKK25736.1 - 1.2 9.8 4.6 7.7 7.2 0.1 3.3 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) D123 PF07065.14 KKK25737.1 - 6.5e-113 376.9 0.1 9.4e-113 376.4 0.1 1.2 1 0 0 1 1 1 1 D123 CENP-I PF07778.11 KKK25738.1 - 5.7e-40 137.5 0.1 2.7e-39 135.3 0.1 1.8 1 1 0 1 1 1 1 Mis6 TBPIP PF07106.13 KKK25738.1 - 0.11 12.5 0.0 0.39 10.7 0.0 2.0 1 0 0 1 1 1 0 TBPIP/Hop2 winged helix domain FANCF PF11107.8 KKK25738.1 - 0.12 11.6 0.0 1.2 8.2 0.0 2.1 2 0 0 2 2 2 0 Fanconi anemia group F protein (FANCF) CLPTM1 PF05602.12 KKK25739.1 - 4e-161 536.8 0.0 4.8e-161 536.6 0.0 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) adh_short PF00106.25 KKK25740.1 - 7.1e-18 64.8 0.0 4.1e-17 62.3 0.0 2.1 2 1 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KKK25740.1 - 5.4e-11 42.5 0.0 9e-11 41.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KKK25740.1 - 0.086 12.7 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 KR domain DUF1640 PF07798.11 KKK25741.1 - 1.9e-36 125.8 4.3 2.5e-36 125.3 4.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) HIP1_clath_bdg PF16515.5 KKK25741.1 - 0.097 13.3 4.5 0.13 12.8 2.6 2.1 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 PUF PF00806.19 KKK25742.1 - 3.7e-66 215.2 14.4 1e-09 37.5 0.0 8.5 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat CPL PF08144.11 KKK25742.1 - 0.00047 20.5 2.3 6.7 7.1 0.0 4.8 2 1 2 4 4 4 2 CPL (NUC119) domain sCache_2 PF17200.4 KKK25742.1 - 0.0017 18.2 1.2 20 5.0 0.0 4.8 4 1 1 5 5 5 1 Single Cache domain 2 Dscam_C PF12355.8 KKK25742.1 - 0.028 15.4 9.3 0.028 15.4 9.3 2.3 2 0 0 2 2 2 0 Down syndrome cell adhesion molecule C terminal DUF234 PF03008.14 KKK25742.1 - 1.1 9.7 2.8 1.9 9.0 0.3 2.5 3 0 0 3 3 3 0 Archaea bacterial proteins of unknown function Tyr-DNA_phospho PF06087.12 KKK25743.1 - 9.5e-86 288.3 0.0 1.8e-66 224.8 0.0 2.1 1 1 1 2 2 2 2 Tyrosyl-DNA phosphodiesterase UIM PF02809.20 KKK25743.1 - 3.1e-06 26.7 8.5 0.00085 19.1 1.3 2.6 2 0 0 2 2 2 2 Ubiquitin interaction motif RAP80_UIM PF18282.1 KKK25743.1 - 0.019 14.8 1.8 4.3 7.2 0.1 2.8 3 0 0 3 3 3 0 RAP80 N-terminal ubiquitin interaction motif HA2 PF04408.23 KKK25744.1 - 6.9e-27 93.9 0.0 6.9e-27 93.9 0.0 3.1 3 0 0 3 3 3 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KKK25744.1 - 2.8e-12 47.0 0.0 1.5e-11 44.6 0.0 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.29 KKK25744.1 - 1e-08 35.2 0.0 3e-08 33.6 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.16 KKK25744.1 - 1.6e-07 31.5 0.0 4.1e-07 30.3 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_22 PF13401.6 KKK25744.1 - 8.2e-05 22.9 0.9 0.00092 19.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 KKK25744.1 - 0.00019 21.5 1.0 0.5 10.4 0.0 3.1 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit T2SSE PF00437.20 KKK25744.1 - 0.007 15.5 0.0 0.016 14.3 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.6 KKK25744.1 - 0.033 14.5 0.0 0.073 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 KKK25744.1 - 0.075 12.4 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family SWI2_SNF2 PF18766.1 KKK25744.1 - 0.2 11.3 2.9 8.2 6.0 0.5 3.0 2 1 0 2 2 2 0 SWI2/SNF2 ATPase CDP-OH_P_transf PF01066.21 KKK25745.1 - 1.4e-14 54.6 1.7 1.4e-14 54.6 1.7 2.0 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase NR_Repeat PF14046.6 KKK25745.1 - 0.34 11.1 3.3 5.2 7.3 0.1 2.5 2 0 0 2 2 2 0 Nuclear receptor repeat Transcrip_reg PF01709.20 KKK25746.1 - 3.9e-69 232.7 1.8 4.7e-69 232.4 1.8 1.1 1 0 0 1 1 1 1 Transcriptional regulator HEAT_2 PF13646.6 KKK25747.1 - 2.2e-09 37.6 1.4 0.018 15.4 0.0 6.0 5 1 1 6 6 6 4 HEAT repeats HEAT PF02985.22 KKK25747.1 - 7.8e-05 22.6 13.6 0.075 13.3 0.0 8.8 11 0 0 11 11 11 2 HEAT repeat Cnd1 PF12717.7 KKK25747.1 - 0.0034 17.4 0.4 16 5.5 0.0 4.9 4 1 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 KKK25747.1 - 0.0056 16.3 2.2 3.3 7.2 0.0 4.7 4 0 0 4 4 4 1 CLASP N terminal HEAT_EZ PF13513.6 KKK25747.1 - 0.033 14.7 9.8 10 6.8 0.0 6.9 7 0 0 7 7 7 0 HEAT-like repeat Vac14_Fab1_bd PF12755.7 KKK25747.1 - 0.044 14.4 0.0 20 5.9 0.0 4.3 4 0 0 4 4 4 0 Vacuolar 14 Fab1-binding region RTP1_C1 PF10363.9 KKK25747.1 - 0.11 12.7 1.5 75 3.6 0.0 5.3 7 0 0 7 7 7 0 Required for nuclear transport of RNA pol II C-terminus 1 PAC3 PF10178.9 KKK25748.1 - 3.9e-06 26.9 0.0 5.9e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Proteasome assembly chaperone 3 cwf21 PF08312.12 KKK25749.1 - 4.6e-20 71.5 10.0 4.6e-20 71.5 10.0 2.7 1 1 1 2 2 2 1 cwf21 domain Tho2 PF11262.8 KKK25749.1 - 1.8 7.7 3.9 2.6 7.2 3.9 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 ABC2_membrane PF01061.24 KKK25750.1 - 4.6e-81 271.2 60.8 3.8e-42 144.1 30.6 2.8 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 KKK25750.1 - 3.7e-38 131.1 0.8 6.7e-20 72.0 0.0 3.1 3 0 0 3 3 2 2 ABC transporter PDR_CDR PF06422.12 KKK25750.1 - 2.3e-28 97.9 11.2 6.8e-27 93.2 0.0 3.4 3 0 0 3 3 2 2 CDR ABC transporter ABC_trans_N PF14510.6 KKK25750.1 - 1.3e-14 54.5 0.2 4.1e-14 53.0 0.2 1.9 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_16 PF13191.6 KKK25750.1 - 7.3e-06 26.5 0.1 0.0028 18.1 0.1 2.5 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 KKK25750.1 - 1.3e-05 25.2 0.0 0.0014 18.6 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_18 PF13238.6 KKK25750.1 - 2.4e-05 24.9 0.0 0.00075 20.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 KKK25750.1 - 3.5e-05 23.9 0.0 0.11 12.6 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_21 PF13304.6 KKK25750.1 - 4.5e-05 23.4 0.0 0.047 13.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 KKK25750.1 - 0.00014 21.1 39.6 0.00063 19.0 12.0 2.7 3 0 0 3 3 2 2 ABC-2 family transporter protein AAA_33 PF13671.6 KKK25750.1 - 0.00016 21.8 1.2 0.013 15.7 0.0 3.0 3 0 0 3 3 2 1 AAA domain AAA_24 PF13479.6 KKK25750.1 - 0.00048 19.9 0.0 0.12 12.1 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_28 PF13521.6 KKK25750.1 - 0.00048 20.4 0.0 0.0029 17.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KKK25750.1 - 0.00057 20.2 0.0 0.042 14.1 0.0 3.1 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KKK25750.1 - 0.00076 19.1 0.0 0.61 9.6 0.2 2.8 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KKK25750.1 - 0.0012 18.6 3.6 0.57 10.0 0.3 3.1 3 0 0 3 3 3 2 P-loop containing region of AAA domain cobW PF02492.19 KKK25750.1 - 0.0018 17.9 0.1 0.039 13.5 0.1 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 KKK25750.1 - 0.0029 17.6 0.3 0.25 11.2 0.2 2.6 2 0 0 2 2 2 1 NACHT domain SMC_N PF02463.19 KKK25750.1 - 0.0039 16.7 0.5 0.076 12.4 0.0 2.9 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain DUF5391 PF17369.2 KKK25750.1 - 0.026 14.6 0.8 0.73 9.9 0.1 2.8 2 0 0 2 2 2 0 Family of unknown function (DUF5391) AAA_30 PF13604.6 KKK25750.1 - 0.059 13.1 1.2 4.4 7.0 0.6 2.4 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 KKK25750.1 - 0.09 13.2 0.0 26 5.3 0.1 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Septin PF00735.18 KKK25750.1 - 0.092 12.0 0.1 0.49 9.6 0.1 2.0 2 0 0 2 2 2 0 Septin TsaE PF02367.17 KKK25750.1 - 0.095 12.7 0.3 0.94 9.5 0.2 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Dynamin_N PF00350.23 KKK25750.1 - 0.098 12.7 0.1 3.2 7.8 0.0 3.1 3 0 0 3 3 3 0 Dynamin family NB-ARC PF00931.22 KKK25750.1 - 0.1 11.8 0.3 3.4 6.8 0.1 2.5 2 0 0 2 2 2 0 NB-ARC domain FtsK_SpoIIIE PF01580.18 KKK25750.1 - 0.14 11.5 0.1 6.8 6.0 0.1 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family Zeta_toxin PF06414.12 KKK25750.1 - 0.27 10.5 1.1 1.7 7.9 0.5 2.2 2 0 0 2 2 2 0 Zeta toxin AAA_17 PF13207.6 KKK25750.1 - 1.9 8.9 6.0 6.3 7.2 0.1 3.5 4 0 0 4 4 3 0 AAA domain CAS_CSE1 PF03378.15 KKK25752.1 - 2.3e-201 669.1 0.9 4.3e-201 668.2 0.0 2.0 3 0 0 3 3 3 1 CAS/CSE protein, C-terminus Cse1 PF08506.10 KKK25752.1 - 1.4e-159 530.9 1.6 1.9e-159 530.4 1.6 1.2 1 0 0 1 1 1 1 Cse1 IBN_N PF03810.19 KKK25752.1 - 3.3e-16 59.0 0.3 1e-15 57.4 0.3 2.0 1 0 0 1 1 1 1 Importin-beta N-terminal domain Xpo1 PF08389.12 KKK25752.1 - 0.0036 17.4 2.8 0.035 14.2 0.1 3.9 5 0 0 5 5 5 1 Exportin 1-like protein UCH_1 PF13423.6 KKK25758.1 - 1.9e-94 316.8 0.2 2.6e-94 316.4 0.2 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.24 KKK25758.1 - 3.7e-16 60.1 0.0 1.4e-15 58.3 0.0 2.0 2 0 0 2 2 2 1 Exonuclease UCH PF00443.29 KKK25758.1 - 8e-06 25.5 0.0 5.2e-05 22.9 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase VHS PF00790.19 KKK25759.1 - 1.7e-31 108.9 0.6 6.8e-24 84.3 0.1 2.4 2 0 0 2 2 2 2 VHS domain SH3_1 PF00018.28 KKK25759.1 - 4.9e-16 58.1 0.0 1.1e-15 56.9 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KKK25759.1 - 6.4e-15 54.7 0.1 1.2e-14 53.9 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KKK25759.1 - 1.1e-13 50.6 0.0 2.1e-13 49.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain GAT PF03127.14 KKK25759.1 - 1.6e-10 41.1 1.6 3.9e-10 39.9 1.6 1.7 1 0 0 1 1 1 1 GAT domain UIM PF02809.20 KKK25759.1 - 0.066 13.2 3.5 0.19 11.7 3.5 1.8 1 0 0 1 1 1 0 Ubiquitin interaction motif Antimicrobial11 PF08106.11 KKK25759.1 - 0.44 10.7 7.5 1.1 9.4 0.1 3.0 2 0 0 2 2 2 0 Formaecin family MMS1_N PF10433.9 KKK25760.1 - 8.7e-157 522.7 0.0 1.2e-156 522.2 0.0 1.2 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 KKK25760.1 - 1e-100 337.2 0.0 4.9e-100 335.0 0.0 2.1 2 0 0 2 2 2 1 CPSF A subunit region ANAPC4_WD40 PF12894.7 KKK25760.1 - 0.033 14.5 0.0 0.45 10.8 0.0 2.9 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain ubiquitin PF00240.23 KKK25761.1 - 9.5e-21 73.3 0.0 1.4e-20 72.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.31 KKK25761.1 - 1.2e-08 34.7 0.3 3e-08 33.4 0.3 1.7 1 0 0 1 1 1 1 UBA/TS-N domain Rad60-SLD PF11976.8 KKK25761.1 - 2.5e-07 30.4 0.0 4.3e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 KKK25761.1 - 4.9e-05 23.8 0.0 0.00012 22.6 0.0 1.5 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.6 KKK25761.1 - 6.7e-05 23.0 0.0 0.00012 22.2 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like YukD PF08817.10 KKK25761.1 - 0.00028 21.5 0.0 0.00067 20.3 0.0 1.7 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukD Ubiquitin_2 PF14560.6 KKK25761.1 - 0.23 12.0 0.0 0.51 10.8 0.0 1.6 1 1 0 1 1 1 0 Ubiquitin-like domain GerD PF17898.1 KKK25761.1 - 0.5 10.3 6.6 0.25 11.3 4.0 1.8 2 1 0 2 2 2 0 Spore germination GerD central core domain STI1 PF17830.1 KKK25761.1 - 2.7 8.0 22.1 1.9 8.5 2.5 3.5 2 1 1 3 3 3 0 STI1 domain UDG PF03167.19 KKK25762.1 - 3.7e-21 75.7 0.0 5.3e-21 75.2 0.0 1.2 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Sporozoite_P67 PF05642.11 KKK25762.1 - 0.014 13.6 1.7 0.017 13.2 1.7 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen XRCC4 PF06632.12 KKK25762.1 - 0.56 9.0 2.2 0.74 8.6 2.2 1.1 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 RhoGEF PF00621.20 KKK25764.1 - 2.3e-20 73.6 0.5 4.3e-20 72.7 0.5 1.5 1 0 0 1 1 1 1 RhoGEF domain SBDS PF01172.18 KKK25765.1 - 2e-23 82.2 0.0 2.3e-23 82.0 0.0 1.0 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein NB-ARC PF00931.22 KKK25765.1 - 0.1 11.8 0.0 0.11 11.7 0.0 1.1 1 0 0 1 1 1 0 NB-ARC domain Phage_TAC_5 PF08890.11 KKK25765.1 - 0.12 12.4 0.0 0.59 10.1 0.0 1.8 2 0 0 2 2 2 0 Phage XkdN-like tail assembly chaperone protein, TAC AAA_7 PF12775.7 KKK25765.1 - 0.22 11.0 0.2 0.44 10.0 0.1 1.5 2 0 0 2 2 2 0 P-loop containing dynein motor region BP28CT PF08146.12 KKK25766.1 - 2.4e-41 141.2 0.3 9.1e-41 139.3 0.3 2.1 1 0 0 1 1 1 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.8 KKK25766.1 - 4.1e-31 107.7 4.7 3e-28 98.5 1.0 4.6 3 0 0 3 3 3 2 U3 small nucleolar RNA-associated protein 10 HEAT_2 PF13646.6 KKK25766.1 - 7.9e-07 29.4 7.9 0.42 11.0 0.2 6.1 5 2 1 6 6 6 4 HEAT repeats HEAT PF02985.22 KKK25766.1 - 5.9e-06 26.1 2.3 0.075 13.3 0.0 5.8 5 0 0 5 5 5 1 HEAT repeat Arm PF00514.23 KKK25766.1 - 0.1 12.7 5.9 11 6.2 0.1 4.7 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 KKK25766.1 - 0.34 11.5 16.4 0.97 10.0 0.5 7.0 9 0 0 9 9 9 0 HEAT-like repeat Bul1_N PF04425.12 KKK25767.1 - 3e-12 46.0 4.4 3.7e-07 29.3 1.5 2.3 1 1 0 2 2 2 2 Bul1 N terminus Arrestin_N PF00339.29 KKK25767.1 - 4.5e-06 26.8 0.0 1.3e-05 25.3 0.0 1.7 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Bul1_C PF04426.12 KKK25767.1 - 0.013 14.9 0.1 0.027 13.9 0.0 1.5 2 0 0 2 2 2 0 Bul1 C terminus Arrestin_C PF02752.22 KKK25767.1 - 0.1 13.1 0.2 3 8.3 0.0 2.5 2 0 0 2 2 2 0 Arrestin (or S-antigen), C-terminal domain NAD_binding_6 PF08030.12 KKK25768.1 - 6.8e-22 78.3 0.0 1e-21 77.7 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KKK25768.1 - 1.4e-21 76.6 0.0 3e-21 75.6 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 KKK25768.1 - 8.3e-19 67.9 13.4 1.7e-18 66.9 13.4 1.6 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.24 KKK25768.1 - 0.069 13.5 0.0 0.15 12.5 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain NRDE-2 PF08424.10 KKK25769.1 - 1.8e-70 237.7 6.6 7e-55 186.4 0.5 3.3 2 1 1 3 3 3 2 NRDE-2, necessary for RNA interference TPR_14 PF13428.6 KKK25769.1 - 0.011 16.5 3.8 26 6.0 0.0 5.3 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_16 PF13432.6 KKK25769.1 - 0.071 13.8 0.2 1.4 9.6 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Ran_BP1 PF00638.18 KKK25770.1 - 7.8e-14 52.0 0.0 1.5e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 RanBP1 domain NUP50 PF08911.11 KKK25770.1 - 0.00068 20.3 2.0 0.00068 20.3 2.0 7.8 8 1 1 9 9 9 1 NUP50 (Nucleoporin 50 kDa) Nucleoporin_FG PF13634.6 KKK25770.1 - 0.0096 16.7 25.8 0.0096 16.7 25.8 12.8 5 3 5 11 11 11 4 Nucleoporin FG repeat region U79_P34 PF03064.16 KKK25770.1 - 0.2 11.0 5.9 0.38 10.1 5.9 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 SNF2_N PF00176.23 KKK25771.1 - 1.1e-65 221.7 0.5 2e-65 220.8 0.5 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KKK25771.1 - 3.3e-16 59.6 0.0 2.7e-15 56.7 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KKK25771.1 - 6.5e-10 39.3 0.3 3.6e-08 33.6 0.0 2.7 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit zf-C3HC4_2 PF13923.6 KKK25771.1 - 8.1e-09 35.2 2.2 8.1e-09 35.2 2.2 2.8 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KKK25771.1 - 1.3e-08 34.5 6.2 5.9e-08 32.5 2.3 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KKK25771.1 - 5e-07 29.6 3.6 5e-07 29.6 3.6 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 KKK25771.1 - 3.8e-06 27.1 6.8 4.1e-06 27.0 4.6 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 KKK25771.1 - 8.6e-06 25.5 8.3 1.3e-05 25.0 3.9 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KKK25771.1 - 1.7e-05 24.7 3.0 1.7e-05 24.7 3.0 2.6 3 0 0 3 3 2 1 zinc-RING finger domain DEAD PF00270.29 KKK25771.1 - 2.1e-05 24.3 0.1 0.0002 21.2 0.0 2.4 2 1 0 2 2 2 1 DEAD/DEAH box helicase Prok-RING_4 PF14447.6 KKK25771.1 - 0.0013 18.6 9.3 0.18 11.7 5.9 3.3 2 1 1 3 3 3 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 KKK25771.1 - 0.0015 18.3 4.9 0.0015 18.3 4.9 2.1 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 KKK25771.1 - 0.0015 18.6 6.0 0.0015 18.6 6.0 2.0 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-RING_14 PF17978.1 KKK25771.1 - 0.01 16.2 0.7 0.033 14.6 0.7 1.9 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_11 PF17123.5 KKK25771.1 - 0.026 14.3 1.2 0.066 13.0 1.2 1.7 1 0 0 1 1 1 0 RING-like zinc finger AAA_34 PF13872.6 KKK25771.1 - 0.033 13.1 0.0 0.061 12.2 0.0 1.3 1 0 0 1 1 1 0 P-loop containing NTP hydrolase pore-1 DZR PF12773.7 KKK25771.1 - 0.31 11.1 5.3 1.3 9.1 3.2 2.4 2 0 0 2 2 2 0 Double zinc ribbon YL1 PF05764.13 KKK25771.1 - 0.78 9.8 24.6 0.064 13.4 14.1 2.3 2 0 0 2 2 2 0 YL1 nuclear protein Baculo_IE-1 PF05290.11 KKK25771.1 - 1.5 8.8 4.5 0.86 9.6 0.4 2.4 2 0 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) TLP-20 PF06088.11 KKK25771.1 - 3.3 7.6 6.1 8.5 6.2 6.1 1.7 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) SCP2 PF02036.17 KKK25772.1 - 2.4e-24 85.7 0.4 3.1e-24 85.4 0.4 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 KKK25772.1 - 1.1e-08 35.4 0.1 1.3e-08 35.1 0.1 1.1 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal SCP2_2 PF13530.6 KKK25772.1 - 0.027 14.9 0.0 0.034 14.5 0.0 1.3 1 0 0 1 1 1 0 Sterol carrier protein domain Nas2_N PF18265.1 KKK25773.1 - 1.1e-26 92.6 0.1 1.7e-26 91.9 0.1 1.3 1 0 0 1 1 1 1 Nas2 N_terminal domain PDZ_6 PF17820.1 KKK25773.1 - 8.9e-11 41.5 0.1 1.4e-10 40.8 0.1 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KKK25773.1 - 5.3e-08 33.1 0.0 1.3e-07 31.9 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 KKK25773.1 - 1.3e-05 25.4 0.0 2.3e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 PDZ domain GRASP55_65 PF04495.14 KKK25773.1 - 7.4e-05 23.1 0.0 0.00011 22.5 0.0 1.4 1 0 0 1 1 1 1 GRASP55/65 PDZ-like domain HMA PF00403.26 KKK25773.1 - 0.02 15.3 0.0 0.058 13.9 0.0 1.7 1 0 0 1 1 1 0 Heavy-metal-associated domain Ras PF00071.22 KKK25774.1 - 1.8e-41 141.4 0.0 2.4e-41 141.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KKK25774.1 - 4.6e-22 78.5 0.0 1.3e-21 77.0 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKK25774.1 - 5.5e-06 26.0 0.1 7.7e-06 25.5 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Ribosomal_S13 PF00416.22 KKK25775.1 - 4.9e-37 127.2 0.9 5.6e-37 127.0 0.9 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 Peptidase_S10 PF00450.22 KKK25776.1 - 1.4e-127 426.6 0.1 1.7e-127 426.3 0.1 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Carbpep_Y_N PF05388.11 KKK25776.1 - 2.8e-10 40.8 0.0 6e-10 39.7 0.0 1.6 1 0 0 1 1 1 1 Carboxypeptidase Y pro-peptide SBDS_C PF09377.10 KKK25777.1 - 2.3e-43 146.9 0.0 3.6e-43 146.3 0.0 1.3 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.18 KKK25777.1 - 9.5e-30 102.5 0.0 1.8e-29 101.7 0.0 1.5 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein Spore_YtfJ PF09579.10 KKK25777.1 - 0.7 10.1 2.9 2.1 8.6 2.9 1.8 1 0 0 1 1 1 0 Sporulation protein YtfJ (Spore_YtfJ) PALP PF00291.25 KKK25778.1 - 4e-39 134.8 3.6 6.9e-38 130.7 3.6 2.0 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Pyridoxal_deC PF00282.19 KKK25780.1 - 9.4e-80 268.1 0.0 1.2e-79 267.8 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain DUF3915 PF13054.6 KKK25781.1 - 0.67 9.9 2.5 1.3 9.0 2.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) Sulfatase PF00884.23 KKK25783.1 - 3.3e-58 197.5 0.3 4.7e-58 197.0 0.3 1.2 1 0 0 1 1 1 1 Sulfatase Choline_sulf_C PF12411.8 KKK25783.1 - 3.7e-21 74.7 0.2 8.5e-21 73.5 0.2 1.7 1 0 0 1 1 1 1 Choline sulfatase enzyme C terminal Phosphodiest PF01663.22 KKK25783.1 - 1.1e-10 41.6 0.0 7.7e-09 35.6 0.0 2.4 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 KKK25783.1 - 0.0098 14.5 0.0 0.013 14.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Sulfatase_C PF14707.6 KKK25783.1 - 0.013 16.2 0.0 0.033 14.9 0.0 1.7 1 0 0 1 1 1 0 C-terminal region of aryl-sulfatase DUF1501 PF07394.12 KKK25783.1 - 0.04 13.0 0.0 0.068 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) AIM5 PF17050.5 KKK25783.1 - 1.2 10.0 3.4 6.5 7.6 3.4 2.3 1 1 0 1 1 1 0 Altered inheritance of mitochondria 5 EMP70 PF02990.16 KKK25784.1 - 3.9e-195 649.4 0.0 5.1e-195 649.1 0.0 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 FANCI_S2 PF14676.6 KKK25814.1 - 0.12 12.7 0.0 0.13 12.6 0.0 1.1 1 0 0 1 1 1 0 FANCI solenoid 2 Ecl1 PF12855.7 KKK25815.1 - 1.2e-37 130.7 28.9 4e-25 90.0 15.5 2.7 3 0 0 3 3 3 2 ECL1/2/3 zinc binding proteins zf-FLZ PF04570.14 KKK25815.1 - 0.061 12.8 0.2 0.12 11.8 0.2 1.5 1 0 0 1 1 1 0 zinc-finger of the FCS-type, C2-C2 RRM_1 PF00076.22 KKK25816.1 - 3.1e-37 126.2 0.0 5.6e-12 45.3 0.0 4.6 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KKK25816.1 - 2.9e-13 49.5 0.0 0.0032 17.3 0.0 4.3 4 0 0 4 4 4 3 Occluded RNA-recognition motif RRM PF10378.9 KKK25816.1 - 4e-08 32.8 3.4 2.7e-07 30.2 3.4 2.6 1 0 0 1 1 1 1 Putative RRM domain DUF4523 PF15023.6 KKK25816.1 - 2.8e-05 24.0 0.0 0.47 10.3 0.0 3.0 3 0 0 3 3 3 2 Protein of unknown function (DUF4523) RRM_7 PF16367.5 KKK25816.1 - 0.00048 20.2 0.0 0.23 11.6 0.0 3.3 3 0 0 3 3 3 1 RNA recognition motif RRM_3 PF08777.11 KKK25816.1 - 0.0013 18.7 0.1 0.72 9.9 0.1 2.9 3 0 0 3 3 3 2 RNA binding motif tRNA-synt_2 PF00152.20 KKK25817.1 - 4.9e-89 298.5 0.0 7.3e-89 297.9 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KKK25817.1 - 1e-05 25.4 0.0 1.8e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Apolipoprotein PF01442.18 KKK25818.1 - 0.00029 20.8 1.6 0.00061 19.7 1.6 1.5 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain ATP-synt_B PF00430.18 KKK25818.1 - 0.011 15.8 0.9 0.021 14.9 0.9 1.4 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) REF PF05755.12 KKK25818.1 - 0.053 13.3 0.2 0.08 12.7 0.2 1.2 1 0 0 1 1 1 0 Rubber elongation factor protein (REF) DUF445 PF04286.12 KKK25818.1 - 0.23 11.2 1.8 0.36 10.6 1.4 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF445) Rhabdo_M1 PF03342.13 KKK25818.1 - 0.25 10.7 2.3 0.42 9.9 2.3 1.3 1 0 0 1 1 1 0 Rhabdovirus M1 matrix protein (M1 polymerase-associated protein) DUF883 PF05957.13 KKK25818.1 - 0.29 11.8 2.0 0.59 10.8 1.7 1.7 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) LsmAD PF06741.13 KKK25818.1 - 0.29 11.7 3.4 0.74 10.4 3.4 1.7 1 0 0 1 1 1 0 LsmAD domain Cdh1_DBD_1 PF18196.1 KKK25818.1 - 0.36 11.2 3.4 0.66 10.3 3.1 1.6 1 1 0 1 1 1 0 Chromodomain helicase DNA-binding domain 1 Iwr1 PF08574.10 KKK25819.1 - 1.6e-20 73.8 7.4 1.6e-20 73.8 7.4 2.8 3 0 0 3 3 3 1 Transcription factor Iwr1 SHE3 PF17078.5 KKK25828.1 - 1.5e-11 44.5 26.7 2.9e-11 43.5 26.7 1.5 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 ATG16 PF08614.11 KKK25828.1 - 0.00038 20.7 36.4 0.021 15.1 16.8 3.1 1 1 1 2 2 2 1 Autophagy protein 16 (ATG16) Spc7 PF08317.11 KKK25828.1 - 0.0044 15.9 34.5 0.0076 15.2 15.7 2.1 1 1 1 2 2 2 2 Spc7 kinetochore protein Filament PF00038.21 KKK25828.1 - 0.032 13.8 35.3 2.7 7.5 35.3 2.2 1 1 0 1 1 1 0 Intermediate filament protein ZapB PF06005.12 KKK25828.1 - 0.046 14.2 2.2 0.046 14.2 2.2 4.3 2 1 1 3 3 2 0 Cell division protein ZapB SlyX PF04102.12 KKK25828.1 - 0.048 14.3 19.7 2.3 8.9 0.4 5.4 1 1 3 5 5 5 0 SlyX TPR_MLP1_2 PF07926.12 KKK25828.1 - 0.069 13.2 31.9 0.052 13.6 15.2 2.7 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Jnk-SapK_ap_N PF09744.9 KKK25828.1 - 0.071 13.3 39.4 0.03 14.5 4.7 3.5 1 1 2 3 3 3 0 JNK_SAPK-associated protein-1 DUF812 PF05667.11 KKK25828.1 - 0.075 11.9 30.4 5.9 5.6 21.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF812) APG6_N PF17675.1 KKK25828.1 - 0.1 13.1 40.5 0.16 12.5 17.4 3.0 1 1 2 3 3 3 0 Apg6 coiled-coil region ADIP PF11559.8 KKK25828.1 - 0.1 12.7 34.4 0.081 13.0 14.2 2.9 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding EzrA PF06160.12 KKK25828.1 - 0.16 10.1 28.5 0.22 9.7 10.2 2.1 1 1 0 2 2 2 0 Septation ring formation regulator, EzrA Tex_N PF09371.10 KKK25828.1 - 0.23 11.1 17.3 0.065 12.9 5.3 2.4 2 0 0 2 2 2 0 Tex-like protein N-terminal domain FAM76 PF16046.5 KKK25828.1 - 0.29 10.5 26.3 0.64 9.3 11.8 2.4 1 1 1 2 2 2 0 FAM76 protein DUF4988 PF16378.5 KKK25828.1 - 0.7 9.5 4.8 0.38 10.4 0.3 2.3 2 1 0 2 2 2 0 Domain of unknown function DUF4407 PF14362.6 KKK25828.1 - 0.74 9.1 21.8 3.7 6.8 19.9 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Bacillus_HBL PF05791.11 KKK25828.1 - 1.1 9.1 11.8 0.91 9.3 1.0 3.2 2 1 2 4 4 4 0 Bacillus haemolytic enterotoxin (HBL) FH2 PF02181.23 KKK25828.1 - 1.6 7.8 21.6 1.4 7.9 6.1 2.5 1 1 1 2 2 2 0 Formin Homology 2 Domain BLOC1_2 PF10046.9 KKK25828.1 - 1.6 9.1 18.0 0.67 10.3 1.5 3.7 1 1 3 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Atg14 PF10186.9 KKK25828.1 - 1.9 7.5 29.6 1.1 8.3 13.2 2.1 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF3584 PF12128.8 KKK25828.1 - 2 5.9 33.2 1.4 6.3 14.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) ALMT PF11744.8 KKK25828.1 - 2.6 6.8 12.8 3.2 6.5 12.8 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter Cep57_MT_bd PF06657.13 KKK25828.1 - 3.3 8.2 27.4 0.089 13.3 4.2 5.0 2 1 1 5 5 5 0 Centrosome microtubule-binding domain of Cep57 TMF_TATA_bd PF12325.8 KKK25828.1 - 3.9 7.7 30.8 0.59 10.4 8.6 4.4 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding TMPIT PF07851.13 KKK25828.1 - 4.7 6.4 27.2 2.3 7.4 7.7 2.7 1 1 2 3 3 3 0 TMPIT-like protein Fib_alpha PF08702.10 KKK25828.1 - 7.2 6.8 22.7 1.9 8.7 5.6 3.3 1 1 2 4 4 4 0 Fibrinogen alpha/beta chain family Csm1_N PF18504.1 KKK25828.1 - 7.8 6.9 24.0 0.54 10.6 6.4 4.7 2 2 3 5 5 5 0 Csm1 N-terminal domain Exonuc_VII_L PF02601.15 KKK25828.1 - 8.5 5.8 28.8 16 5.0 17.3 2.1 1 1 1 2 2 2 0 Exonuclease VII, large subunit DUF5344 PF17279.2 KKK25828.1 - 8.8 7.0 12.4 1.7 9.3 2.2 3.4 1 1 1 3 3 3 0 Family of unknown function (DUF5344) PCI PF01399.27 KKK25830.1 - 2.2e-11 44.2 0.0 4.7e-11 43.1 0.0 1.6 1 0 0 1 1 1 1 PCI domain RPN7 PF10602.9 KKK25830.1 - 4.1e-09 36.4 0.6 7.5e-09 35.5 0.6 1.4 1 0 0 1 1 1 1 26S proteasome subunit RPN7 TPR_19 PF14559.6 KKK25830.1 - 0.0018 18.7 1.2 0.052 14.1 0.2 3.0 1 1 1 2 2 2 2 Tetratricopeptide repeat Herpes_UL14 PF03580.14 KKK25830.1 - 0.0079 16.5 4.4 0.29 11.4 0.7 2.6 1 1 1 2 2 2 2 Herpesvirus UL14-like protein DUF5578 PF17741.1 KKK25830.1 - 0.038 13.4 1.0 0.069 12.6 0.5 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5578) FAD_binding_2 PF00890.24 KKK25831.1 - 1.5e-84 284.5 1.3 1.9e-84 284.2 1.3 1.1 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.28 KKK25831.1 - 5.4e-21 74.5 0.0 2.1e-19 69.4 0.0 2.8 3 0 0 3 3 3 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.24 KKK25831.1 - 5.3e-14 52.6 0.4 9.9e-14 51.7 0.4 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 KKK25831.1 - 1.6e-09 37.7 1.1 7.1e-09 35.5 1.1 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KKK25831.1 - 6.4e-08 32.7 2.6 3.1e-07 30.5 0.5 3.1 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KKK25831.1 - 4.1e-07 29.5 0.9 1.1e-05 24.9 0.8 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KKK25831.1 - 4.5e-06 25.6 5.4 0.0047 15.7 0.3 3.2 3 0 0 3 3 3 2 HI0933-like protein Pyr_redox_3 PF13738.6 KKK25831.1 - 4.7e-06 26.1 0.1 0.022 14.0 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KKK25831.1 - 5.3e-05 22.6 0.1 9.2e-05 21.8 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 KKK25831.1 - 0.00076 18.8 1.3 0.044 13.0 0.6 2.3 2 0 0 2 2 2 1 Thi4 family GIDA PF01134.22 KKK25831.1 - 0.0012 18.0 2.9 0.27 10.3 0.9 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A Amino_oxidase PF01593.24 KKK25831.1 - 0.0017 17.7 0.7 0.92 8.7 0.0 2.9 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 KKK25831.1 - 0.0081 16.7 1.7 6.1 7.5 0.0 2.8 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KKK25831.1 - 0.016 15.2 2.5 0.21 11.6 2.5 2.5 1 1 0 1 1 1 0 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.21 KKK25831.1 - 0.091 12.0 0.4 0.18 11.1 0.4 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FlgD_ig PF13860.6 KKK25831.1 - 0.12 12.3 0.9 0.28 11.1 0.0 2.0 2 0 0 2 2 2 0 FlgD Ig-like domain zf-CCCH PF00642.24 KKK25832.1 - 5.9e-13 48.4 30.1 6.7e-06 25.9 1.3 5.3 5 0 0 5 5 5 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KKK25832.1 - 2.1e-08 33.9 28.1 0.047 13.8 0.9 6.0 5 1 0 5 5 5 4 Zinc finger domain zf-CCCH_3 PF15663.5 KKK25832.1 - 0.00034 20.8 17.6 0.0054 16.9 1.4 3.5 2 2 1 3 3 3 2 Zinc-finger containing family zf-C3H1 PF10650.9 KKK25832.1 - 0.00053 19.7 5.1 0.12 12.2 0.0 4.3 4 0 0 4 4 4 1 Putative zinc-finger domain zf-CCCH_4 PF18044.1 KKK25832.1 - 0.0011 18.6 23.3 0.0016 18.2 0.0 5.4 5 1 0 5 5 5 2 CCCH-type zinc finger Torus PF16131.5 KKK25832.1 - 0.012 16.3 26.2 0.34 11.6 0.5 4.8 2 1 3 5 5 5 0 Torus domain zf-CCCH_2 PF14608.6 KKK25832.1 - 0.027 15.0 1.8 0.027 15.0 1.8 4.5 5 0 0 5 5 5 0 RNA-binding, Nab2-type zinc finger TFIIF_beta PF02270.15 KKK25833.1 - 2e-29 101.5 0.8 3.7e-29 100.7 0.8 1.4 1 0 0 1 1 1 1 TFIIF, beta subunit HTH domain TFIIF_beta_N PF17683.1 KKK25833.1 - 2.7e-28 99.3 0.4 5.7e-28 98.3 0.4 1.6 1 0 0 1 1 1 1 TFIIF, beta subunit N-terminus Tau95 PF09734.9 KKK25833.1 - 0.015 16.1 2.3 0.035 14.9 2.3 1.7 1 1 0 1 1 1 0 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain Sel1 PF08238.12 KKK25834.1 - 7.6e-15 55.0 0.2 8.7e-06 26.2 0.0 3.9 4 0 0 4 4 4 3 Sel1 repeat bZIP_1 PF00170.21 KKK25835.1 - 2.3e-07 30.8 20.4 9.3e-07 28.9 14.9 2.5 2 0 0 2 2 2 1 bZIP transcription factor bZIP_Maf PF03131.17 KKK25835.1 - 2.5e-07 31.1 10.5 2.5e-07 31.1 10.5 2.4 2 0 0 2 2 2 1 bZIP Maf transcription factor bZIP_2 PF07716.15 KKK25835.1 - 6.8e-07 29.3 18.9 3.8e-06 26.9 11.5 2.6 2 0 0 2 2 2 2 Basic region leucine zipper Capsule_synth PF05159.14 KKK25835.1 - 0.018 14.5 0.9 0.039 13.4 0.0 1.9 2 0 0 2 2 2 0 Capsule polysaccharide biosynthesis protein Tho2 PF11262.8 KKK25835.1 - 3.6 6.7 14.4 1.5 8.0 11.8 1.5 1 1 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 DUF745 PF05335.13 KKK25835.1 - 4.5 6.9 10.8 15 5.2 10.8 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF745) CBF PF03914.17 KKK25836.1 - 1.1e-37 129.6 0.2 2.3e-37 128.6 0.2 1.6 1 0 0 1 1 1 1 CBF/Mak21 family Titin_Ig-rpts PF06582.12 KKK25836.1 - 0.062 13.2 0.6 0.14 12.1 0.6 1.5 1 0 0 1 1 1 0 Titin repeat Mt_ATP-synt_B PF05405.14 KKK25837.1 - 3.3e-53 179.7 8.3 4.4e-53 179.3 8.3 1.2 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) DUF1539 PF07560.11 KKK25837.1 - 0.08 13.0 0.6 0.24 11.5 0.4 1.8 1 1 1 2 2 2 0 Domain of Unknown Function (DUF1539) V_ATPase_I PF01496.19 KKK25837.1 - 0.29 9.0 5.3 0.38 8.6 5.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Hrs_helical PF12210.8 KKK25837.1 - 2.8 8.5 8.3 2.7 8.6 2.3 2.6 1 1 1 2 2 2 0 Hepatocyte growth factor-regulated tyrosine kinase substrate GPI-anchored PF10342.9 KKK25838.1 - 5.4e-14 52.7 1.3 1.2e-13 51.6 1.3 1.5 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Big_5 PF13205.6 KKK25838.1 - 0.049 14.3 0.6 0.095 13.4 0.1 1.8 2 0 0 2 2 2 0 Bacterial Ig-like domain DUF2120 PF09893.9 KKK25839.1 - 0.029 14.5 0.1 0.041 14.0 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2120) APG6 PF04111.12 KKK25840.1 - 8.7e-74 247.3 0.0 1.3e-73 246.8 0.0 1.3 1 0 0 1 1 1 1 Apg6 BARA domain APG6_N PF17675.1 KKK25840.1 - 1.2e-38 132.6 8.8 1.9e-38 132.0 8.8 1.3 1 0 0 1 1 1 1 Apg6 coiled-coil region tRNA-synt_2c PF01411.19 KKK25840.1 - 0.017 13.6 0.4 0.024 13.1 0.4 1.1 1 0 0 1 1 1 0 tRNA synthetases class II (A) PTPlike_phytase PF14566.6 KKK25840.1 - 0.15 12.2 0.6 0.35 11.0 0.6 1.6 1 0 0 1 1 1 0 Inositol hexakisphosphate MbeD_MobD PF04899.12 KKK25840.1 - 2.7 8.2 5.6 29 4.9 0.7 2.8 3 0 0 3 3 3 0 MbeD/MobD like Amidase PF01425.21 KKK25841.1 - 3.5e-97 326.2 0.0 1.2e-96 324.5 0.0 1.7 1 1 0 1 1 1 1 Amidase DUF4032 PF13224.6 KKK25841.1 - 0.14 12.0 0.0 0.28 11.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4032) DUF1815 PF08844.10 KKK25841.1 - 0.15 12.0 0.0 0.36 10.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1815) Arylsulfotran_2 PF14269.6 KKK25842.1 - 3.5e-43 148.1 0.1 5.2e-43 147.5 0.1 1.3 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 KKK25842.1 - 1.5e-14 53.7 0.0 8.3e-13 48.0 0.0 2.1 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) NlpE PF04170.12 KKK25842.1 - 0.083 13.9 0.3 30 5.7 0.0 2.9 2 1 1 3 3 3 0 NlpE N-terminal domain TPP_enzyme_N PF02776.18 KKK25843.1 - 9.3e-47 158.8 0.1 2.5e-45 154.2 0.0 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 KKK25843.1 - 5.4e-38 129.8 0.2 1.2e-37 128.7 0.1 1.7 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 KKK25843.1 - 5.3e-17 62.0 0.1 1.2e-16 60.8 0.1 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain B12-binding PF02310.19 KKK25843.1 - 0.011 15.7 0.3 0.029 14.4 0.3 1.6 1 0 0 1 1 1 0 B12 binding domain CO_dh PF02552.16 KKK25843.1 - 0.19 11.5 0.0 0.33 10.7 0.0 1.3 1 0 0 1 1 1 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit Piwi PF02171.17 KKK25844.1 - 2.8e-70 237.0 0.0 4.4e-70 236.3 0.0 1.3 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 KKK25844.1 - 4.3e-19 69.5 0.0 9e-19 68.5 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL2 PF16488.5 KKK25844.1 - 2.7e-10 40.4 0.0 2.3e-09 37.5 0.0 2.4 2 0 0 2 2 2 1 Argonaute linker 2 domain ArgoL1 PF08699.10 KKK25844.1 - 4.8e-10 39.0 0.0 2.8e-09 36.5 0.0 2.2 2 0 0 2 2 2 1 Argonaute linker 1 domain PAZ PF02170.22 KKK25844.1 - 1e-06 28.6 0.0 2.1e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 PAZ domain ArgoMid PF16487.5 KKK25844.1 - 0.0025 18.0 0.0 0.0055 16.9 0.0 1.6 1 0 0 1 1 1 1 Mid domain of argonaute Scm3 PF10384.9 KKK25845.1 - 3.2e-22 78.0 0.3 7.5e-22 76.8 0.3 1.7 1 0 0 1 1 1 1 Centromere protein Scm3 Myb_DNA-binding PF00249.31 KKK25845.1 - 7.5e-07 29.2 0.1 0.029 14.6 0.1 3.2 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KKK25845.1 - 5.9e-05 23.2 1.7 0.35 11.2 0.2 3.4 3 0 0 3 3 3 2 Myb-like DNA-binding domain DUF4674 PF15719.5 KKK25845.1 - 0.39 10.7 0.1 0.39 10.7 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4674) PALP PF00291.25 KKK25846.1 - 7.6e-58 196.2 0.3 9e-58 196.0 0.3 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Methyltransf_28 PF02636.17 KKK25847.1 - 1.2e-40 139.8 0.0 1.7e-40 139.3 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase PRMT5 PF05185.16 KKK25847.1 - 0.16 11.8 0.0 0.28 11.0 0.0 1.4 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase TPR_1 PF00515.28 KKK25848.1 - 1e-23 82.1 2.7 2.8e-08 33.2 0.1 5.8 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 KKK25848.1 - 3.1e-23 80.0 2.5 1.8e-07 30.7 0.1 5.9 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_11 PF13414.6 KKK25848.1 - 8.1e-20 70.2 2.6 5.3e-09 35.6 0.1 4.9 4 1 1 5 5 5 3 TPR repeat TPR_16 PF13432.6 KKK25848.1 - 1.4e-18 67.3 2.7 1.2e-05 25.8 0.0 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 KKK25848.1 - 1.6e-16 59.6 1.1 8.2e-05 23.1 0.0 5.7 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.6 KKK25848.1 - 1.3e-14 53.4 1.8 0.0078 16.5 0.1 5.0 5 0 0 5 5 4 4 Tetratricopeptide repeat TPR_19 PF14559.6 KKK25848.1 - 1.1e-13 51.4 2.8 0.00048 20.6 0.0 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 KKK25848.1 - 6e-13 47.9 0.8 2.8e-06 27.1 0.0 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 KKK25848.1 - 8.9e-12 44.2 1.5 0.0069 16.3 0.0 6.4 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_12 PF13424.6 KKK25848.1 - 1.2e-11 44.7 2.1 7.8e-07 29.3 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_20 PF14561.6 KKK25848.1 - 5.3e-11 42.7 0.2 0.008 16.5 0.0 4.7 2 2 2 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 KKK25848.1 - 2.1e-08 34.2 1.0 0.0024 18.0 0.1 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 KKK25848.1 - 1.7e-06 28.3 1.6 1.2 10.0 0.0 6.0 6 0 0 6 6 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KKK25848.1 - 6.2e-06 26.4 1.4 0.0008 19.6 0.1 2.7 2 1 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 KKK25848.1 - 0.0004 19.7 0.6 0.49 9.6 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_3 PF07720.12 KKK25848.1 - 0.00093 19.1 0.1 0.16 12.0 0.0 3.1 3 0 0 3 3 2 1 Tetratricopeptide repeat MIT PF04212.18 KKK25848.1 - 0.0021 18.1 0.5 4.9 7.3 0.1 4.0 4 0 0 4 4 4 1 MIT (microtubule interacting and transport) domain TPR_10 PF13374.6 KKK25848.1 - 0.0096 15.8 6.2 0.064 13.2 0.9 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat NatB_MDM20 PF09797.9 KKK25848.1 - 0.017 14.1 0.0 0.046 12.6 0.0 1.7 2 0 0 2 2 2 0 N-acetyltransferase B complex (NatB) non catalytic subunit DUF1641 PF07849.11 KKK25848.1 - 0.078 12.9 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1641) TOM20_plant PF06552.12 KKK25848.1 - 0.086 12.6 0.1 2.6 7.7 0.0 3.0 3 1 0 3 3 3 0 Plant specific mitochondrial import receptor subunit TOM20 Spt20 PF12090.8 KKK25848.1 - 0.26 10.9 2.1 0.48 10.0 2.1 1.4 1 0 0 1 1 1 0 Spt20 family DUF4192 PF13830.6 KKK25848.1 - 1.2 9.1 7.9 14 5.6 7.9 2.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4192) RRM_1 PF00076.22 KKK25849.1 - 7.6e-32 109.0 0.0 1.7e-18 66.2 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Fungal_trans PF04082.18 KKK25849.1 - 1.7e-13 50.3 0.2 6.4e-13 48.3 0.0 1.9 1 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK25849.1 - 3.5e-06 27.0 11.7 5.9e-06 26.3 11.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HSBP1 PF06825.12 KKK25849.1 - 0.036 13.9 0.3 0.097 12.5 0.3 1.7 1 0 0 1 1 1 0 Heat shock factor binding protein 1 DUF962 PF06127.11 KKK25851.1 - 1.7e-24 85.7 0.1 3.5e-24 84.7 0.1 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF962) Osw5 PF17062.5 KKK25851.1 - 0.065 13.3 0.5 0.15 12.1 0.5 1.7 1 0 0 1 1 1 0 Outer spore wall 5 SHS2_Rpb7-N PF03876.17 KKK25852.1 - 6e-15 55.4 0.0 1.2e-14 54.4 0.0 1.5 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 KKK25852.1 - 3e-10 40.3 0.0 4.6e-10 39.7 0.0 1.2 1 0 0 1 1 1 1 S1 RNA binding domain THF_DHG_CYH PF00763.23 KKK25853.1 - 3.4e-24 85.3 0.0 5.1e-24 84.8 0.0 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.19 KKK25853.1 - 1.6e-12 47.1 0.0 1.9e-09 37.1 0.0 2.5 2 1 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain ATP-synt_ab PF00006.25 KKK25854.1 - 1.3e-72 244.0 0.0 2e-72 243.3 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 KKK25854.1 - 5.9e-48 162.4 0.6 1.1e-47 161.5 0.6 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 KKK25854.1 - 9.6e-15 54.9 3.2 2.4e-14 53.6 3.2 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain EMC3_TMCO1 PF01956.16 KKK25855.1 - 6.7e-51 172.4 0.8 8.7e-51 172.0 0.8 1.1 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like SPC25 PF06703.11 KKK25856.1 - 6.9e-52 175.5 0.1 8.4e-52 175.2 0.1 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) MMS19_C PF12460.8 KKK25857.1 - 3.2e-127 425.2 17.4 8.3e-126 420.5 12.2 3.3 3 1 0 3 3 3 2 RNAPII transcription regulator C-terminal MMS19_N PF14500.6 KKK25857.1 - 4.8e-94 314.8 2.7 4.8e-93 311.5 0.1 3.1 3 0 0 3 3 3 1 Dos2-interacting transcription regulator of RNA-Pol-II HEAT_2 PF13646.6 KKK25857.1 - 1.5e-05 25.3 4.7 4 7.9 0.1 6.2 6 0 0 6 6 6 2 HEAT repeats HEAT_EZ PF13513.6 KKK25857.1 - 0.00037 20.9 8.1 1.3 9.6 0.5 5.8 6 0 0 6 6 6 1 HEAT-like repeat HEAT PF02985.22 KKK25857.1 - 0.0071 16.5 6.8 6.2 7.4 0.1 6.2 7 0 0 7 7 7 1 HEAT repeat RTP1_C1 PF10363.9 KKK25857.1 - 0.081 13.1 7.4 0.26 11.5 0.0 4.3 5 0 0 5 5 5 0 Required for nuclear transport of RNA pol II C-terminus 1 Arm PF00514.23 KKK25857.1 - 0.66 10.1 2.9 31 4.8 0.0 3.6 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat FANCI_S2 PF14676.6 KKK25857.1 - 1.8 8.9 4.4 9.7 6.5 0.2 3.9 3 1 0 4 4 4 0 FANCI solenoid 2 Fasciclin PF02469.22 KKK25858.1 - 1.2e-06 28.7 0.0 1.9e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Fasciclin domain WD40 PF00400.32 KKK25860.1 - 5.5e-13 49.2 3.4 0.076 13.9 0.3 6.7 7 0 0 7 7 7 4 WD domain, G-beta repeat Sin3a_C PF16879.5 KKK25861.1 - 2.3e-80 270.4 6.1 2.3e-80 270.4 6.1 2.6 3 0 0 3 3 3 1 C-terminal domain of Sin3a protein PAH PF02671.21 KKK25861.1 - 9.2e-44 147.3 7.4 1.3e-17 63.7 0.0 4.1 4 0 0 4 4 4 3 Paired amphipathic helix repeat Sin3_corepress PF08295.12 KKK25861.1 - 2.7e-39 133.2 1.1 5.1e-39 132.3 0.1 2.0 2 0 0 2 2 2 1 Sin3 family co-repressor ESM4 PF15952.5 KKK25861.1 - 0.098 13.1 3.6 0.37 11.2 3.6 2.0 1 0 0 1 1 1 0 Enhancer of split M4 family AcetylCoA_hydro PF02550.15 KKK25862.1 - 2.8e-52 177.6 0.0 4.1e-52 177.1 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain AcetylCoA_hyd_C PF13336.6 KKK25862.1 - 9.6e-40 136.0 0.0 1.9e-39 135.1 0.0 1.5 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain Gpi16 PF04113.14 KKK25876.1 - 9.1e-241 800.2 0.0 1.1e-240 799.9 0.0 1.0 1 0 0 1 1 1 1 Gpi16 subunit, GPI transamidase component SPOC PF07744.13 KKK25877.1 - 3.4e-24 85.5 0.0 5.7e-24 84.8 0.0 1.4 1 0 0 1 1 1 1 SPOC domain TFIIS_M PF07500.14 KKK25877.1 - 8.2e-22 77.8 0.0 1.7e-21 76.8 0.0 1.5 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain PHD PF00628.29 KKK25877.1 - 6e-11 42.1 12.4 1.2e-10 41.1 12.4 1.5 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 KKK25877.1 - 0.12 12.0 4.3 0.23 11.1 4.3 1.5 1 0 0 1 1 1 0 PHD-finger MecA PF05389.12 KKK25877.1 - 0.66 9.6 2.3 10 5.6 2.3 2.6 1 1 0 1 1 1 0 Negative regulator of genetic competence (MecA) PHD_3 PF13922.6 KKK25877.1 - 0.79 10.2 6.6 0.13 12.7 0.4 2.9 2 0 0 2 2 2 0 PHD domain of transcriptional enhancer, Asx IL17R_fnIII_D2 PF16578.5 KKK25878.1 - 0.076 13.6 0.0 0.55 10.8 0.0 2.1 2 0 0 2 2 2 0 Interleukin 17 receptor D FtsJ PF01728.19 KKK25879.1 - 1.3e-52 178.5 0.0 6.9e-52 176.1 0.0 1.9 1 1 0 1 1 1 1 FtsJ-like methyltransferase 4HBT PF03061.22 KKK25880.1 - 8.5e-09 35.6 0.1 1.5e-08 34.9 0.1 1.4 1 0 0 1 1 1 1 Thioesterase superfamily SUIM_assoc PF16619.5 KKK25880.1 - 0.071 13.2 0.4 0.071 13.2 0.4 2.5 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 DEAD PF00270.29 KKK25881.1 - 5e-41 140.4 0.0 1e-40 139.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KKK25881.1 - 1.6e-27 96.1 0.0 8.9e-27 93.6 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KKK25881.1 - 0.017 15.2 0.5 0.064 13.3 0.0 2.1 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Presenilin PF01080.17 KKK25881.1 - 5.7 5.6 5.1 10 4.8 5.1 1.3 1 0 0 1 1 1 0 Presenilin LUC7 PF03194.15 KKK25882.1 - 7.5e-74 248.6 1.5 8.7e-74 248.4 1.5 1.0 1 0 0 1 1 1 1 LUC7 N_terminus MCPsignal PF00015.21 KKK25882.1 - 0.018 14.8 0.0 0.027 14.3 0.0 1.3 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain TelA PF05816.11 KKK25882.1 - 0.052 12.6 1.6 0.079 12.0 0.5 1.7 2 0 0 2 2 2 0 Toxic anion resistance protein (TelA) HMG_box_5 PF14887.6 KKK25882.1 - 0.089 12.8 0.1 1.2 9.1 0.0 2.3 1 1 1 2 2 2 0 HMG (high mobility group) box 5 PIN_8 PF18476.1 KKK25882.1 - 0.11 12.4 0.1 1.1 9.1 0.0 2.0 2 0 0 2 2 2 0 PIN like domain zinc-ribbons_6 PF07191.12 KKK25882.1 - 0.13 12.3 0.4 0.33 10.9 0.2 1.7 2 0 0 2 2 2 0 zinc-ribbons Snf7 PF03357.21 KKK25882.1 - 0.28 10.8 4.8 0.22 11.1 2.4 2.0 2 1 0 2 2 2 0 Snf7 Occludin_ELL PF07303.13 KKK25882.1 - 0.88 10.3 4.0 1.5 9.6 0.1 2.7 2 1 0 2 2 2 0 Occludin homology domain TFIIA PF03153.13 KKK25883.1 - 0.024 14.6 18.7 0.031 14.3 18.7 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF932 PF06067.11 KKK25883.1 - 0.24 11.2 8.1 0.055 13.2 0.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF932) Ribosomal_L29 PF00831.23 KKK25883.1 - 3.6 7.6 10.3 0.16 12.0 0.7 3.2 3 0 0 3 3 3 0 Ribosomal L29 protein FF PF01846.19 KKK25884.1 - 4.9e-13 49.0 6.6 3.5e-10 39.9 0.1 3.6 3 0 0 3 3 3 3 FF domain WW PF00397.26 KKK25884.1 - 7.9e-10 38.7 3.1 7.9e-10 38.7 3.1 3.0 3 0 0 3 3 3 2 WW domain DUF4200 PF13863.6 KKK25884.1 - 0.87 10.0 26.4 0.82 10.1 8.5 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4200) Proteasome PF00227.26 KKK25885.1 - 1.4e-61 207.4 0.2 1.7e-61 207.1 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KKK25885.1 - 3.5e-13 49.0 0.1 8.9e-13 47.7 0.1 1.8 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DUF5624 PF18538.1 KKK25885.1 - 0.015 15.4 0.5 0.046 13.8 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5624) SHE3 PF17078.5 KKK25886.1 - 0.0014 18.4 1.7 0.0018 18.0 1.7 1.1 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 Takusan PF04822.13 KKK25886.1 - 0.13 12.2 1.9 0.24 11.3 0.9 1.9 2 0 0 2 2 2 0 Takusan MYO10_CC PF16735.5 KKK25886.1 - 0.56 10.3 10.2 0.26 11.4 4.4 2.3 1 1 2 3 3 3 0 Unconventional myosin-X coiled coil domain NAD_binding_10 PF13460.6 KKK25887.1 - 2.3e-08 34.2 0.3 3.5e-08 33.6 0.3 1.4 1 1 0 1 1 1 1 NAD(P)H-binding HIM1 PF08732.10 KKK25887.1 - 1.5e-06 27.8 0.0 2.4e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 HIM1 NmrA PF05368.13 KKK25887.1 - 1.6e-05 24.6 0.8 9.3e-05 22.1 0.0 2.0 2 0 0 2 2 2 1 NmrA-like family Epimerase PF01370.21 KKK25887.1 - 2.6e-05 23.8 0.0 5.9e-05 22.6 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 KKK25887.1 - 7.4e-05 23.2 0.1 0.0031 17.9 0.0 2.2 1 1 1 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.12 KKK25887.1 - 0.0014 17.9 0.1 0.74 8.9 0.0 2.1 1 1 1 2 2 2 2 Male sterility protein DapB_N PF01113.20 KKK25887.1 - 0.075 13.2 0.0 0.47 10.6 0.0 2.1 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Tht1 PF04163.12 KKK25888.1 - 0.0092 14.8 10.9 0.0065 15.3 8.2 1.9 2 1 0 2 2 2 1 Tht1-like nuclear fusion protein Laps PF10169.9 KKK25888.1 - 0.044 14.3 0.7 0.097 13.3 0.7 1.6 1 0 0 1 1 1 0 Learning-associated protein GspH PF12019.8 KKK25888.1 - 0.17 12.3 1.7 0.23 11.9 0.1 2.1 2 0 0 2 2 2 0 Type II transport protein GspH Med2 PF11214.8 KKK25888.1 - 0.43 10.8 8.5 2.1 8.5 1.5 3.5 1 1 2 3 3 3 0 Mediator complex subunit 2 MukF_M PF17192.4 KKK25888.1 - 0.49 10.1 8.8 1.2 8.9 1.0 2.5 2 0 0 2 2 2 0 MukF middle domain Ribosomal_L6 PF00347.23 KKK25889.1 - 7.5e-24 84.2 0.1 7.4e-12 45.8 0.0 2.6 2 1 0 2 2 2 2 Ribosomal protein L6 Inositol_P PF00459.25 KKK25890.1 - 3.5e-52 177.6 0.5 9.1e-52 176.2 0.5 1.6 1 1 0 1 1 1 1 Inositol monophosphatase family FAD_binding_1 PF00667.20 KKK25891.1 - 8.6e-63 211.9 0.0 1.5e-62 211.0 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain POR PF01558.18 KKK25891.1 - 1.8e-10 41.2 0.1 5e-10 39.7 0.1 1.7 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase NAD_binding_1 PF00175.21 KKK25891.1 - 2.4e-09 37.8 0.0 6.1e-09 36.5 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain PFOR_II PF17147.4 KKK25891.1 - 7e-07 29.5 0.1 2.2e-06 27.9 0.1 1.8 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II Transketolase_C PF02780.20 KKK25891.1 - 0.00042 20.2 0.1 0.0016 18.3 0.1 2.0 1 0 0 1 1 1 1 Transketolase, C-terminal domain Proteasome PF00227.26 KKK25895.1 - 3.1e-43 147.5 0.3 1.8e-33 115.6 0.1 2.0 2 0 0 2 2 2 2 Proteasome subunit WD40 PF00400.32 KKK25896.1 - 4e-55 182.5 20.4 8.2e-12 45.5 0.2 7.7 8 0 0 8 8 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKK25896.1 - 1e-22 80.2 0.0 3.8e-05 23.9 0.0 6.2 3 1 4 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KKK25896.1 - 4.2e-09 35.8 0.7 0.33 9.9 0.0 4.9 1 1 4 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KKK25896.1 - 5.1e-09 36.3 0.0 0.0042 17.0 0.0 2.6 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KKK25896.1 - 2.8e-07 29.6 2.2 0.27 9.8 0.1 4.8 2 2 2 4 4 4 4 Nucleoporin Nup120/160 WD40_like PF17005.5 KKK25896.1 - 1.1e-05 25.0 0.0 0.028 13.7 0.0 3.4 3 1 1 4 4 4 2 WD40-like domain PD40 PF07676.12 KKK25896.1 - 0.0001 22.1 0.0 4.4 7.4 0.0 4.5 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat VID27 PF08553.10 KKK25896.1 - 0.011 14.8 0.2 2.1 7.3 0.0 3.3 2 1 2 4 4 4 0 VID27 C-terminal WD40-like domain Frtz PF11768.8 KKK25896.1 - 0.032 12.5 0.0 0.074 11.4 0.0 1.5 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz CHAP PF05257.16 KKK25896.1 - 0.053 14.1 4.6 0.15 12.7 0.3 3.2 3 0 0 3 3 3 0 CHAP domain PALB2_WD40 PF16756.5 KKK25896.1 - 0.14 11.0 0.9 0.72 8.7 0.1 2.4 1 1 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain IKI3 PF04762.12 KKK25896.1 - 0.31 9.0 0.0 0.51 8.3 0.0 1.3 1 0 0 1 1 1 0 IKI3 family Exo_endo_phos PF03372.23 KKK25897.1 - 1.4e-19 70.6 0.0 2.8e-19 69.6 0.0 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Luciferase_cat PF10285.9 KKK25897.1 - 0.17 11.3 0.2 0.33 10.3 0.0 1.5 2 0 0 2 2 2 0 Luciferase catalytic domain S_4TM PF18159.1 KKK25897.1 - 0.22 10.8 0.1 0.39 10.0 0.1 1.3 1 0 0 1 1 1 0 SMODS-associating 4TM effector domain RED_N PF07808.13 KKK25898.1 - 1.4e-07 31.4 3.8 1.8e-07 31.0 1.9 2.2 2 1 0 2 2 2 1 RED-like protein N-terminal region FNIP_N PF14636.6 KKK25898.1 - 0.024 15.6 8.4 0.024 15.6 8.4 2.8 2 1 0 2 2 2 0 Folliculin-interacting protein N-terminus GvpG PF05120.12 KKK25898.1 - 0.087 12.8 1.3 0.24 11.4 0.4 2.1 2 0 0 2 2 2 0 Gas vesicle protein G Glyco_hydro_cc PF11790.8 KKK25899.1 - 2.8e-64 216.9 1.6 3.2e-64 216.7 1.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core MFS_1 PF07690.16 KKK25900.1 - 3.3e-34 118.4 25.8 3.3e-34 118.4 25.8 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.7 KKK25900.1 - 1.1 8.0 12.3 0.02 13.8 3.9 2.1 3 0 0 3 3 3 0 MFS_1 like family SWI-SNF_Ssr4 PF08549.10 KKK25901.1 - 1.5e-223 744.6 1.5 2.3e-223 743.9 1.5 1.2 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1750) Laminin_I PF06008.14 KKK25901.1 - 0.2 11.4 3.9 0.31 10.7 3.9 1.2 1 0 0 1 1 1 0 Laminin Domain I Thi4 PF01946.17 KKK25902.1 - 8.3e-111 368.9 0.0 1e-110 368.6 0.0 1.1 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 KKK25902.1 - 1.2e-07 31.7 0.3 2.1e-07 30.8 0.3 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KKK25902.1 - 3.6e-06 27.1 0.2 2.1e-05 24.7 0.2 2.4 2 1 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KKK25902.1 - 7.3e-05 22.0 0.4 0.00013 21.1 0.4 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_9 PF13454.6 KKK25902.1 - 0.00081 19.4 0.9 0.002 18.2 0.1 2.0 2 1 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 KKK25902.1 - 0.0013 18.0 0.0 0.0022 17.3 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KKK25902.1 - 0.0094 15.1 0.5 0.033 13.3 0.5 1.9 2 0 0 2 2 2 1 FAD binding domain FAD_binding_3 PF01494.19 KKK25902.1 - 0.041 13.1 0.0 0.059 12.6 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.6 KKK25902.1 - 0.053 12.8 0.0 0.088 12.0 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KKK25902.1 - 0.11 11.9 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Trp_halogenase PF04820.14 KKK25902.1 - 0.12 11.2 0.2 0.17 10.7 0.2 1.1 1 0 0 1 1 1 0 Tryptophan halogenase HI0933_like PF03486.14 KKK25902.1 - 0.21 10.2 0.4 0.32 9.6 0.4 1.2 1 0 0 1 1 1 0 HI0933-like protein Mqo PF06039.15 KKK25902.1 - 0.23 10.0 0.0 0.73 8.3 0.0 1.7 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) Ppx-GppA PF02541.16 KKK25903.1 - 3.5e-43 148.1 0.0 5.1e-43 147.5 0.0 1.2 1 0 0 1 1 1 1 Ppx/GppA phosphatase family GDA1_CD39 PF01150.17 KKK25903.1 - 0.0067 15.1 0.1 0.015 14.0 0.0 1.5 2 0 0 2 2 2 1 GDA1/CD39 (nucleoside phosphatase) family Pil1 PF13805.6 KKK25904.1 - 1.1e-85 287.4 7.4 1.9e-85 286.6 7.4 1.4 1 0 0 1 1 1 1 Eisosome component PIL1 APG6_N PF17675.1 KKK25904.1 - 1 9.9 10.8 0.087 13.4 3.5 2.5 2 0 0 2 2 2 0 Apg6 coiled-coil region RCR PF12273.8 KKK25905.1 - 1.2e-22 80.8 11.4 1.6e-22 80.4 11.4 1.2 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red LysE PF01810.18 KKK25905.1 - 0.003 17.0 0.3 0.004 16.6 0.3 1.1 1 0 0 1 1 1 1 LysE type translocator SARAF PF06682.12 KKK25905.1 - 0.0046 16.7 0.9 0.0057 16.4 0.9 1.3 1 1 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis CYYR1 PF10873.8 KKK25905.1 - 0.0093 16.4 2.6 0.0093 16.4 2.6 1.8 1 1 1 2 2 2 1 Cysteine and tyrosine-rich protein 1 Acyl_transf_3 PF01757.22 KKK25905.1 - 0.06 12.4 1.0 0.077 12.0 1.0 1.1 1 0 0 1 1 1 0 Acyltransferase family DUF2207 PF09972.9 KKK25905.1 - 0.11 11.3 0.1 0.13 11.0 0.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF1180 PF06679.12 KKK25905.1 - 1.2 9.5 0.0 1.2 9.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) DUF4381 PF14316.6 KKK25905.1 - 5.3 7.3 7.4 14 5.9 5.6 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4381) Arf PF00025.21 KKK25906.1 - 5.4e-42 143.2 0.0 6e-42 143.0 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 KKK25906.1 - 1.5e-18 66.9 0.0 1.7e-18 66.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KKK25906.1 - 4.1e-15 56.0 0.0 6.6e-15 55.4 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 KKK25906.1 - 2.5e-08 34.0 0.0 3.8e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KKK25906.1 - 1.1e-06 28.2 0.0 1.3e-06 27.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 KKK25906.1 - 4e-06 26.4 0.0 4.7e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 KKK25906.1 - 0.00032 20.0 0.1 0.00076 18.7 0.0 1.9 2 1 0 2 2 2 1 G-protein alpha subunit Dynamin_N PF00350.23 KKK25906.1 - 0.006 16.6 0.1 0.047 13.8 0.1 2.0 1 1 1 2 2 2 1 Dynamin family MMR_HSR1_Xtn PF16897.5 KKK25906.1 - 0.0064 16.5 0.0 0.01 15.8 0.0 1.3 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain FeoB_N PF02421.18 KKK25906.1 - 0.009 15.6 0.2 0.07 12.6 0.0 2.2 2 1 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KKK25906.1 - 0.066 13.1 0.1 9 6.2 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase Pkinase PF00069.25 KKK25907.1 - 5e-13 49.0 0.0 6.4e-13 48.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK25907.1 - 0.0099 15.2 0.1 0.023 14.0 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase RNA_pol_Rpb2_6 PF00562.28 KKK25908.1 - 1.2e-117 393.3 0.0 1.6e-117 392.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 KKK25908.1 - 4.3e-35 121.1 0.0 1.3e-34 119.5 0.0 1.7 1 1 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.16 KKK25908.1 - 1e-27 96.1 0.0 3.1e-27 94.5 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_2 PF04561.14 KKK25908.1 - 3.1e-26 92.2 0.0 5.2e-26 91.4 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpa2_4 PF06883.12 KKK25908.1 - 9.9e-26 89.5 0.0 2.2e-25 88.4 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_7 PF04560.20 KKK25908.1 - 1.4e-15 57.4 0.0 1.4e-14 54.3 0.0 2.3 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 7 zf-CCCH_2 PF14608.6 KKK25909.1 - 6e-12 45.6 60.4 0.00012 22.4 14.0 5.5 5 0 0 5 5 5 5 RNA-binding, Nab2-type zinc finger ABC2_membrane PF01061.24 KKK25910.1 - 4.6e-34 117.7 30.8 3.7e-20 72.3 4.6 4.1 4 0 0 4 4 4 3 ABC-2 type transporter PDR_CDR PF06422.12 KKK25910.1 - 4e-28 97.2 0.1 8.7e-26 89.7 0.0 2.8 2 0 0 2 2 2 1 CDR ABC transporter ABC_tran PF00005.27 KKK25910.1 - 5e-19 69.2 0.0 8.5e-19 68.4 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_25 PF13481.6 KKK25910.1 - 0.0014 18.3 0.1 0.0025 17.4 0.1 1.3 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 KKK25910.1 - 0.0014 18.6 0.0 0.0052 16.7 0.0 1.8 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 KKK25910.1 - 0.0029 18.0 0.1 0.0053 17.2 0.1 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 KKK25910.1 - 0.05 13.4 0.1 0.05 13.4 0.1 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_21 PF13304.6 KKK25910.1 - 0.07 12.9 0.1 3.1 7.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 KKK25910.1 - 0.16 12.3 0.2 0.45 10.8 0.2 1.9 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KKK25910.1 - 0.39 10.9 1.2 0.78 10.0 1.2 1.4 1 0 0 1 1 1 0 AAA domain Mago-bind PF09282.10 KKK25911.1 - 9.9e-14 50.9 6.4 1.9e-13 50.0 6.4 1.5 1 0 0 1 1 1 1 Mago binding Amino_oxidase PF01593.24 KKK25912.1 - 1.3e-27 97.2 0.0 1.7e-27 96.8 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KKK25912.1 - 3.2e-15 56.1 0.1 1.3e-14 54.1 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KKK25912.1 - 1.3e-11 44.8 0.1 5.7e-07 29.4 0.0 2.5 2 1 0 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.17 KKK25912.1 - 0.00053 19.3 0.0 0.001 18.4 0.0 1.4 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 KKK25912.1 - 0.00078 18.6 0.0 0.0043 16.2 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 KKK25912.1 - 0.0012 18.1 0.0 0.0087 15.3 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KKK25912.1 - 0.0041 16.5 0.0 0.011 15.1 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KKK25912.1 - 0.0065 16.5 0.1 0.063 13.3 0.0 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 KKK25912.1 - 0.011 16.3 0.0 0.93 10.1 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KKK25912.1 - 0.055 12.2 0.0 0.16 10.7 0.0 1.7 2 0 0 2 2 2 0 HI0933-like protein GMC_oxred_N PF00732.19 KKK25912.1 - 0.1 12.0 0.0 0.23 10.8 0.0 1.6 1 0 0 1 1 1 0 GMC oxidoreductase GGDEF_2 PF17853.1 KKK25912.1 - 0.13 12.5 0.2 0.44 10.8 0.1 2.0 2 0 0 2 2 1 0 GGDEF-like domain MCRA PF06100.11 KKK25912.1 - 0.22 10.3 0.0 0.35 9.6 0.0 1.3 1 0 0 1 1 1 0 MCRA family zf-UBR PF02207.20 KKK25913.1 - 8.9e-19 67.4 15.3 2.4e-18 66.0 15.3 1.8 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.17 KKK25913.1 - 0.0049 16.6 0.0 0.013 15.3 0.0 1.7 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS zf-RING_5 PF14634.6 KKK25913.1 - 0.0058 16.6 0.7 0.0058 16.6 0.7 4.0 3 1 1 4 4 4 1 zinc-RING finger domain zf-RING_2 PF13639.6 KKK25913.1 - 0.0097 16.2 0.6 0.0097 16.2 0.6 4.4 4 1 1 5 5 5 1 Ring finger domain BUD22 PF09073.10 KKK25913.1 - 7.9 5.7 12.0 14 4.9 12.0 1.3 1 0 0 1 1 1 0 BUD22 UCR_UQCRX_QCR9 PF05365.12 KKK25914.1 - 1.4e-25 89.0 1.4 1.7e-25 88.7 1.4 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like DUF3533 PF12051.8 KKK25925.1 - 2.6e-95 319.5 7.1 3.8e-95 319.0 7.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) Inhibitor_I36 PF03995.13 KKK25925.1 - 0.097 12.6 0.2 3.5 7.6 0.1 2.3 2 0 0 2 2 2 0 Peptidase inhibitor family I36 DUF1054 PF06335.12 KKK25925.1 - 0.12 12.3 0.0 0.19 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1054) Cu-oxidase_3 PF07732.15 KKK25926.1 - 3.3e-47 159.4 3.3 2.8e-46 156.4 0.2 3.4 3 1 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 KKK25926.1 - 1.4e-39 135.0 6.4 2.5e-36 124.5 1.0 3.7 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 KKK25926.1 - 7.2e-38 130.2 0.4 3e-37 128.2 0.2 2.2 2 0 0 2 2 2 1 Multicopper oxidase Phosphoesterase PF04185.14 KKK25927.1 - 2.5e-35 122.4 7.4 4.5e-34 118.2 7.2 2.2 1 1 0 1 1 1 1 Phosphoesterase family DNA_ligase_C PF17879.1 KKK25927.1 - 0.03 14.4 0.1 0.062 13.4 0.1 1.5 1 0 0 1 1 1 0 DNA ligase C-terminal domain HIF-1a_CTAD PF08778.10 KKK25927.1 - 0.074 12.7 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 HIF-1 alpha C terminal transactivation domain DUF1635 PF07795.11 KKK25928.1 - 0.071 13.0 0.1 0.1 12.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) A_deaminase PF00962.22 KKK25929.1 - 1.5e-20 73.8 0.0 3.5e-20 72.6 0.0 1.4 1 1 0 1 1 1 1 Adenosine/AMP deaminase Acetyltransf_13 PF13880.6 KKK25934.1 - 3.8e-30 103.7 0.0 8.4e-30 102.6 0.0 1.6 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.6 KKK25934.1 - 1.6e-15 56.6 0.6 2.9e-15 55.8 0.6 1.4 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO TolA_bind_tri PF16331.5 KKK25935.1 - 0.17 11.9 0.0 0.33 11.1 0.0 1.4 1 0 0 1 1 1 0 TolA binding protein trimerisation Haspin_kinase PF12330.8 KKK25935.1 - 2.6 6.9 3.8 3.7 6.4 3.8 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Fungal_lectin_2 PF18647.1 KKK25936.1 - 7.7e-27 93.7 0.1 9e-26 90.3 0.0 2.3 2 0 0 2 2 2 1 Alpha-galactosyl-binding fungal lectin Lipase_GDSL_2 PF13472.6 KKK25936.1 - 2.7e-14 54.0 0.2 4.1e-12 46.9 0.0 2.4 2 0 0 2 2 2 2 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KKK25936.1 - 1.8e-07 31.3 0.0 2.2e-06 27.8 0.0 2.2 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Glyco_hydro_18 PF00704.28 KKK25937.1 - 3.3e-17 63.2 0.0 3.9e-17 63.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Zn_clus PF00172.18 KKK25938.1 - 3.8e-09 36.5 8.1 6e-09 35.9 8.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KKK25938.1 - 9.8e-08 31.3 0.5 2.4e-07 30.1 0.5 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain UQ_con PF00179.26 KKK25939.1 - 6.4e-47 158.7 0.0 1.1e-46 157.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Acyl-CoA_dh_N PF02771.16 KKK25939.1 - 6.1e-24 84.9 0.1 1.1e-23 84.1 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 KKK25939.1 - 1.4e-22 80.5 0.1 2.2e-22 79.9 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KKK25939.1 - 6.6e-17 61.5 0.0 1.2e-16 60.6 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KKK25939.1 - 1.7e-07 31.6 0.3 3.1e-07 30.7 0.3 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Prok-E2_B PF14461.6 KKK25939.1 - 0.014 15.1 0.0 0.056 13.1 0.0 1.9 2 0 0 2 2 2 0 Prokaryotic E2 family B RWD PF05773.22 KKK25939.1 - 0.18 12.1 0.0 0.32 11.3 0.0 1.4 1 0 0 1 1 1 0 RWD domain Glyoxalase PF00903.25 KKK25940.1 - 0.0059 16.8 0.0 0.04 14.1 0.0 2.3 3 0 0 3 3 3 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Gly-zipper_Omp PF13488.6 KKK25940.1 - 0.017 15.1 0.7 0.017 15.1 0.7 1.9 2 0 0 2 2 2 0 Glycine zipper Rick_17kDa_Anti PF05433.15 KKK25940.1 - 0.86 9.5 9.4 0.061 13.2 3.7 2.1 2 0 0 2 2 2 0 Glycine zipper 2TM domain EMG1 PF03587.14 KKK25941.1 - 1.6e-80 269.4 0.0 1.9e-80 269.2 0.0 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase Peptidase_C107 PF17222.3 KKK25941.1 - 0.14 11.1 0.0 0.21 10.5 0.0 1.2 1 0 0 1 1 1 0 Viral cysteine endopeptidase C107 PIP5K PF01504.18 KKK25942.1 - 7.8e-100 333.6 0.0 1.4e-99 332.7 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase CENP-R PF06729.12 KKK25942.1 - 0.044 13.7 0.0 0.13 12.2 0.0 1.8 1 0 0 1 1 1 0 Kinetochore component, CENP-R zf-CCHC_6 PF15288.6 KKK25942.1 - 0.3 11.0 2.6 0.64 9.9 2.6 1.5 1 0 0 1 1 1 0 Zinc knuckle XPG_I PF00867.18 KKK25943.1 - 3.1e-32 110.8 1.4 1.1e-31 109.1 0.0 2.3 2 0 0 2 2 2 1 XPG I-region XPG_N PF00752.17 KKK25943.1 - 1e-31 109.4 0.5 5.5e-31 107.0 0.0 2.3 2 0 0 2 2 2 1 XPG N-terminal domain 5_3_exonuc PF01367.20 KKK25943.1 - 6.2e-05 23.5 0.4 0.00039 21.0 0.0 2.4 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold Linker_histone PF00538.19 KKK25944.1 - 1.7e-25 89.2 0.1 1.7e-25 89.2 0.1 2.0 2 1 0 2 2 2 1 linker histone H1 and H5 family MIP PF00230.20 KKK25945.1 - 2.4e-33 115.7 3.6 3.4e-33 115.2 3.6 1.2 1 0 0 1 1 1 1 Major intrinsic protein Fungal_trans_2 PF11951.8 KKK25945.1 - 3.1e-19 69.0 4.4 5.8e-19 68.2 4.4 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK25945.1 - 7.9e-08 32.3 8.9 1.5e-07 31.4 8.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gly-zipper_Omp PF13488.6 KKK25945.1 - 5.6 7.0 5.2 5.5 7.1 1.0 2.7 2 1 0 2 2 2 0 Glycine zipper CFEM PF05730.11 KKK25946.1 - 0.022 14.8 11.7 0.16 12.1 11.7 2.3 1 1 0 1 1 1 0 CFEM domain Voldacs PF03517.13 KKK25948.1 - 0.052 13.7 0.6 0.16 12.1 0.6 1.8 1 0 0 1 1 1 0 Regulator of volume decrease after cellular swelling Myc_N PF01056.18 KKK25948.1 - 0.15 11.9 2.0 0.3 11.0 2.0 1.4 1 0 0 1 1 1 0 Myc amino-terminal region ABC2_membrane PF01061.24 KKK25949.1 - 6.6e-78 260.9 46.6 8.6e-44 149.5 14.2 2.5 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 KKK25949.1 - 2.4e-38 131.8 0.0 1.6e-18 67.5 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 KKK25949.1 - 1.3e-27 95.5 4.3 8.5e-25 86.5 0.0 3.4 3 0 0 3 3 3 2 CDR ABC transporter AAA_16 PF13191.6 KKK25949.1 - 3.7e-07 30.7 0.1 0.00033 21.1 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain ABC2_membrane_3 PF12698.7 KKK25949.1 - 5.7e-07 29.0 21.5 0.00052 19.2 8.8 2.5 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_25 PF13481.6 KKK25949.1 - 4.7e-05 23.0 0.1 0.0028 17.2 0.1 2.3 2 0 0 2 2 2 1 AAA domain ABC_trans_N PF14510.6 KKK25949.1 - 5.5e-05 23.7 0.0 0.00014 22.4 0.0 1.7 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_22 PF13401.6 KKK25949.1 - 0.00039 20.7 0.4 1.1 9.6 0.1 2.9 2 1 0 2 2 2 2 AAA domain AAA_18 PF13238.6 KKK25949.1 - 0.00039 21.0 0.0 2.3 8.7 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.6 KKK25949.1 - 0.00082 19.1 0.3 0.087 12.6 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KKK25949.1 - 0.002 18.1 0.1 0.012 15.5 0.0 2.0 2 0 0 2 2 2 1 RsgA GTPase AAA_33 PF13671.6 KKK25949.1 - 0.0024 18.0 0.1 1.2 9.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 KKK25949.1 - 0.0064 16.8 1.4 1.3 9.2 0.6 2.4 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 KKK25949.1 - 0.014 15.0 1.8 1.9 8.0 0.5 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_21 PF13304.6 KKK25949.1 - 0.032 14.0 0.0 3.2 7.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system NACHT PF05729.12 KKK25949.1 - 0.039 13.9 0.7 3 7.7 0.1 2.3 2 0 0 2 2 2 0 NACHT domain AAA_30 PF13604.6 KKK25949.1 - 0.084 12.6 0.8 7.3 6.3 0.2 2.3 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 KKK25949.1 - 0.12 12.8 0.1 20 5.6 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.6 KKK25949.1 - 0.18 12.2 0.3 7.7 6.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 KKK25949.1 - 0.22 11.3 0.6 9 6.0 0.2 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF805 PF05656.14 KKK25949.1 - 1.1 9.7 8.7 12 6.4 0.8 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF805) Rhodanese PF00581.20 KKK25950.1 - 3.7e-16 59.6 0.0 1.7e-08 34.9 0.0 2.1 2 0 0 2 2 2 2 Rhodanese-like domain DUF202 PF02656.15 KKK25951.1 - 1e-16 61.1 0.0 2.3e-16 60.0 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF202) DUF2243 PF10002.9 KKK25951.1 - 0.13 12.3 0.1 0.42 10.7 0.0 1.7 2 0 0 2 2 2 0 Predicted membrane protein (DUF2243) Lactamase_B PF00753.27 KKK25952.1 - 2.1e-16 60.5 1.6 2.8e-16 60.1 1.6 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily SLAC1 PF03595.17 KKK25953.1 - 5.4e-96 321.7 54.6 6.1e-96 321.5 54.6 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel DUF2156 PF09924.9 KKK25955.1 - 5.6e-30 104.4 0.0 8.1e-30 103.9 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2156) Lipase_GDSL_2 PF13472.6 KKK25956.1 - 1.5e-12 48.3 0.1 2.4e-12 47.6 0.1 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KKK25956.1 - 1.1e-10 41.9 0.0 1.6e-10 41.3 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.6 KKK25956.1 - 0.012 15.8 0.1 1.3 9.1 0.0 2.2 1 1 1 2 2 2 0 GDSL-like Lipase/Acylhydrolase family JSRP PF15312.6 KKK25956.1 - 0.053 13.4 0.4 0.13 12.2 0.4 1.6 1 0 0 1 1 1 0 Junctional sarcoplasmic reticulum protein CBM_1 PF00734.18 KKK25957.1 - 3.7e-14 52.4 9.1 3.7e-14 52.4 9.1 2.7 2 1 0 2 2 2 1 Fungal cellulose binding domain DPBB_1 PF03330.18 KKK25957.1 - 9.4e-07 29.0 0.4 9.4e-07 29.0 0.4 2.1 2 0 0 2 2 2 1 Lytic transglycolase Mucin PF01456.17 KKK25957.1 - 0.8 9.7 46.7 1.6 8.8 46.7 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Aa_trans PF01490.18 KKK25958.1 - 5.1e-21 74.9 34.7 6.4e-21 74.5 34.7 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF4401 PF14351.6 KKK25958.1 - 3.6 6.8 36.1 0.29 10.4 17.1 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4401) DUF3759 PF12585.8 KKK25959.1 - 3.1e-40 136.1 6.7 3.7e-40 135.8 6.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) Glyco_tranf_2_3 PF13641.6 KKK25960.1 - 1.6e-17 64.1 0.0 3.2e-17 63.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 KKK25960.1 - 8.6e-15 55.2 6.5 8.6e-15 55.2 6.5 2.7 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 KKK25960.1 - 8.9e-15 54.9 0.0 1.3e-14 54.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 KKK25960.1 - 2.3e-07 30.5 0.0 3.9e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 FKBP_C PF00254.28 KKK25961.1 - 6.6e-34 116.1 0.0 7.8e-34 115.9 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase APH PF01636.23 KKK25962.1 - 1.4e-06 28.4 0.0 4.6e-05 23.4 0.0 2.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KKK25962.1 - 0.087 12.4 1.7 0.15 11.7 0.1 1.9 2 0 0 2 2 2 0 Choline/ethanolamine kinase Zn_clus PF00172.18 KKK25963.1 - 5.6e-11 42.4 8.1 1.1e-10 41.5 8.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KKK25963.1 - 1.9e-09 37.0 0.6 5e-09 35.6 0.4 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Herpes_UL95 PF03038.14 KKK25963.1 - 0.085 12.0 0.2 0.2 10.8 0.2 1.6 1 1 0 1 1 1 0 UL95 family GTP_EFTU PF00009.27 KKK25981.1 - 1.3e-05 24.9 0.0 1.5e-05 24.7 0.0 1.0 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gly_transf_sug PF04488.15 KKK25983.1 - 6.3e-11 42.8 0.0 1.5e-10 41.5 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif MIP PF00230.20 KKK26021.1 - 2e-54 184.7 5.0 2.5e-54 184.4 5.0 1.1 1 0 0 1 1 1 1 Major intrinsic protein ABC2_membrane PF01061.24 KKK26022.1 - 7.1e-29 100.7 7.8 1e-28 100.2 7.8 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 KKK26022.1 - 3.3e-18 66.5 0.0 6.8e-18 65.5 0.0 1.6 1 0 0 1 1 1 1 ABC transporter ABC_trans_N PF14510.6 KKK26022.1 - 0.00015 22.3 0.0 0.00038 21.0 0.0 1.8 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_18 PF13238.6 KKK26022.1 - 0.026 15.1 0.0 0.069 13.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 KKK26022.1 - 0.14 12.6 0.0 0.28 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KKK26022.1 - 0.14 12.4 0.0 0.39 11.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain Peptidase_M28 PF04389.17 KKK26023.1 - 2.5e-40 138.3 0.0 4.9e-40 137.3 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 KKK26023.1 - 1.1e-11 44.6 0.1 2.2e-11 43.6 0.1 1.5 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 KKK26023.1 - 0.00045 20.0 0.0 0.0011 18.7 0.0 1.7 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 FGGY_C PF02782.16 KKK26024.1 - 6.5e-75 251.2 0.2 1.3e-74 250.3 0.2 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 KKK26024.1 - 8.2e-70 235.1 0.0 1.1e-69 234.7 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain COesterase PF00135.28 KKK26045.1 - 7.6e-44 150.4 0.0 2.5e-43 148.7 0.0 1.7 1 1 0 1 1 1 1 Carboxylesterase family Clathrin PF00637.20 KKK26047.1 - 1e-198 651.2 34.1 7.9e-32 110.1 2.3 7.7 7 0 0 7 7 7 7 Region in Clathrin and VPS Clathrin_propel PF01394.20 KKK26047.1 - 2.6e-38 128.5 1.0 1.5e-08 34.5 0.0 6.7 6 0 0 6 6 6 6 Clathrin propeller repeat Clathrin_H_link PF13838.6 KKK26047.1 - 7.8e-32 109.0 4.0 8e-32 109.0 0.3 3.1 3 0 0 3 3 3 1 Clathrin-H-link TPR_14 PF13428.6 KKK26047.1 - 1.7e-05 25.2 1.6 0.39 11.7 0.1 6.5 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.6 KKK26047.1 - 0.0002 21.3 1.4 0.38 11.1 0.0 5.3 4 0 0 4 4 4 1 Tetratricopeptide repeat Coatomer_WDAD PF04053.14 KKK26047.1 - 0.0075 15.4 4.8 0.17 10.9 0.3 3.5 4 0 0 4 4 4 1 Coatomer WD associated region TPR_7 PF13176.6 KKK26047.1 - 0.057 13.5 4.8 1e+02 3.2 0.0 6.0 6 0 0 6 6 6 0 Tetratricopeptide repeat Utp13 PF08625.11 KKK26047.1 - 0.11 12.5 1.9 5.7 6.8 0.1 4.1 4 0 0 4 4 4 0 Utp13 specific WD40 associated domain TPR_1 PF00515.28 KKK26047.1 - 0.65 9.9 3.4 6.6 6.7 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat Vps39_1 PF10366.9 KKK26047.1 - 1.8 8.9 11.2 7.5 6.9 0.0 5.8 5 1 1 6 6 6 0 Vacuolar sorting protein 39 domain 1 CPSase_L_D2 PF02786.17 KKK26048.1 - 1.9e-81 272.6 0.1 3.1e-81 271.9 0.1 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.18 KKK26048.1 - 2.7e-69 232.9 0.0 4.3e-69 232.2 0.0 1.4 1 0 0 1 1 1 1 Conserved carboxylase domain Biotin_carb_N PF00289.22 KKK26048.1 - 5.5e-39 133.1 0.0 1.1e-38 132.1 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 KKK26048.1 - 1.2e-30 105.8 0.0 3.7e-30 104.2 0.0 1.9 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.19 KKK26048.1 - 1.1e-26 94.0 0.0 2.3e-26 93.0 0.0 1.5 1 0 0 1 1 1 1 HMGL-like Biotin_lipoyl PF00364.22 KKK26048.1 - 1.4e-18 66.5 2.8 1.4e-18 66.5 2.8 2.2 2 0 0 2 2 2 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 KKK26048.1 - 4.9e-10 39.3 0.0 9.6e-10 38.3 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.6 KKK26048.1 - 6.7e-10 38.6 2.9 1.5e-05 24.7 0.2 3.1 2 1 1 3 3 3 2 Biotin-lipoyl like ATP-grasp PF02222.22 KKK26048.1 - 8.7e-08 31.9 0.0 1.8e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 KKK26048.1 - 6.1e-05 23.1 0.0 0.00016 21.8 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain HlyD_3 PF13437.6 KKK26048.1 - 0.00014 22.5 0.5 0.44 11.3 0.1 3.5 3 0 0 3 3 3 1 HlyD family secretion protein RimK PF08443.11 KKK26048.1 - 0.00045 19.9 0.0 0.002 17.8 0.0 2.0 1 1 0 1 1 1 1 RimK-like ATP-grasp domain HlyD_D23 PF16576.5 KKK26048.1 - 0.00054 19.2 0.2 0.036 13.3 0.1 2.3 1 1 1 2 2 2 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion ATP-grasp_4 PF13535.6 KKK26048.1 - 0.01 15.4 0.0 0.025 14.2 0.0 1.7 1 0 0 1 1 1 0 ATP-grasp domain DUF2118 PF09891.9 KKK26048.1 - 0.037 14.0 0.2 0.1 12.6 0.2 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2118) GCV_H PF01597.19 KKK26048.1 - 0.12 12.3 1.1 0.4 10.6 0.5 2.1 1 1 1 2 2 2 0 Glycine cleavage H-protein NQRA PF05896.11 KKK26048.1 - 0.12 11.7 0.2 0.22 10.9 0.2 1.3 1 0 0 1 1 1 0 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) RnfC_N PF13375.6 KKK26048.1 - 0.27 11.2 2.3 1.8 8.6 2.0 2.3 1 1 0 1 1 1 0 RnfC Barrel sandwich hybrid domain Hydrolase PF00702.26 KKK26050.1 - 8.4e-15 55.6 0.0 1.3e-11 45.2 0.0 2.1 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KKK26050.1 - 1.6e-14 54.4 0.0 2.8e-14 53.6 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KKK26050.1 - 5.4e-06 26.4 0.1 1.5e-05 24.9 0.1 1.7 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 KKK26050.1 - 0.00025 21.5 0.0 0.001 19.5 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.10 KKK26050.1 - 0.0081 15.8 0.0 0.27 10.8 0.0 2.5 2 1 0 2 2 2 1 Mitochondrial PGP phosphatase Hydrolase_6 PF13344.6 KKK26050.1 - 0.039 14.1 0.0 0.13 12.4 0.0 1.8 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase DUF1771 PF08590.10 KKK26052.1 - 2.2e-08 34.4 8.8 3.9e-08 33.5 8.8 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) CUE PF02845.16 KKK26052.1 - 1.9e-07 30.6 0.0 4.7e-05 23.0 0.0 3.3 3 0 0 3 3 3 1 CUE domain Smr PF01713.21 KKK26052.1 - 0.0012 19.2 0.1 0.0034 17.7 0.1 1.8 2 0 0 2 2 2 1 Smr domain DMA PF03474.14 KKK26052.1 - 0.032 13.8 0.0 0.086 12.5 0.0 1.7 1 0 0 1 1 1 0 DMRTA motif GPI-anchored PF10342.9 KKK26053.1 - 1.7e-17 63.9 2.3 1.7e-17 63.9 2.3 1.8 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family LT-IIB PF06453.11 KKK26053.1 - 0.065 13.1 0.1 0.1 12.5 0.1 1.3 1 0 0 1 1 1 0 Type II heat-labile enterotoxin , B subunit (LT-IIB) DUF212 PF02681.14 KKK26053.1 - 0.089 12.9 2.7 0.081 13.1 1.3 1.7 2 0 0 2 2 2 0 Divergent PAP2 family RE_ApaLI PF09499.10 KKK26053.1 - 0.15 11.8 0.0 0.2 11.3 0.0 1.2 1 0 0 1 1 1 0 ApaLI-like restriction endonuclease RL11D PF11088.8 KKK26053.1 - 0.33 11.3 2.7 0.54 10.6 0.2 2.0 2 0 0 2 2 2 0 Glycoprotein encoding membrane proteins RL5A and RL6 RebB PF11747.8 KKK26053.1 - 0.35 11.0 8.3 5.2 7.2 3.3 2.6 1 1 1 2 2 2 0 Killing trait TRP PF06011.12 KKK26054.1 - 5.5e-171 569.0 27.5 6.9e-171 568.7 27.5 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 KKK26054.1 - 2.7e-41 141.2 0.8 4.6e-41 140.5 0.8 1.4 1 0 0 1 1 1 1 ML-like domain Rab5ip PF07019.12 KKK26054.1 - 0.051 14.2 10.4 0.057 14.0 1.1 3.4 3 0 0 3 3 3 0 Rab5-interacting protein (Rab5ip) Shisa PF13908.6 KKK26054.1 - 0.11 12.8 0.6 12 6.1 0.0 3.2 3 0 0 3 3 3 0 Wnt and FGF inhibitory regulator Ac76 PF05814.11 KKK26054.1 - 0.95 9.5 11.7 1.8 8.6 0.2 3.7 3 1 1 4 4 4 0 Orf76 (Ac76) DUF4834 PF16118.5 KKK26054.1 - 2.9 8.9 6.8 15 6.6 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) DUF3742 PF12553.8 KKK26054.1 - 6.1 7.0 14.4 0.91 9.7 0.4 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF3742) DEAD PF00270.29 KKK26055.1 - 8.8e-47 159.1 0.0 1.6e-46 158.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KKK26055.1 - 2.3e-23 82.7 0.0 1.4e-22 80.1 0.0 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 KKK26055.1 - 1.7e-18 66.6 0.1 3.2e-18 65.7 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) eIF-3c_N PF05470.12 KKK26055.1 - 0.00097 17.6 2.3 0.0012 17.3 2.3 1.1 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus ERCC3_RAD25_C PF16203.5 KKK26055.1 - 0.0025 17.0 0.0 0.0025 17.0 0.0 2.4 2 0 0 2 2 1 1 ERCC3/RAD25/XPB C-terminal helicase Pox_Ag35 PF03286.14 KKK26055.1 - 0.11 12.2 17.1 0.22 11.3 17.1 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein TRAP_alpha PF03896.16 KKK26055.1 - 0.19 10.9 11.2 0.33 10.1 11.2 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit SDA1 PF05285.12 KKK26055.1 - 0.21 11.0 24.8 0.36 10.2 24.8 1.3 1 0 0 1 1 1 0 SDA1 DDHD PF02862.17 KKK26055.1 - 0.24 11.5 2.5 0.45 10.6 2.5 1.5 1 0 0 1 1 1 0 DDHD domain VIT1 PF01988.19 KKK26055.1 - 0.27 11.1 0.7 0.53 10.1 0.5 1.6 1 1 0 1 1 1 0 VIT family Myc_N PF01056.18 KKK26055.1 - 0.29 11.0 15.7 0.51 10.2 15.7 1.3 1 0 0 1 1 1 0 Myc amino-terminal region FAM60A PF15396.6 KKK26055.1 - 0.39 10.7 8.3 0.75 9.8 8.3 1.5 1 0 0 1 1 1 0 Protein Family FAM60A RNA_pol_3_Rpc31 PF11705.8 KKK26055.1 - 0.42 10.8 26.9 0.82 9.9 26.9 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Spore_coat_CotO PF14153.6 KKK26055.1 - 0.62 10.0 22.9 1.1 9.1 22.9 1.3 1 0 0 1 1 1 0 Spore coat protein CotO Zip PF02535.22 KKK26055.1 - 0.64 9.2 5.9 1 8.5 5.9 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Nop14 PF04147.12 KKK26055.1 - 0.66 8.1 25.4 0.88 7.7 25.4 1.1 1 0 0 1 1 1 0 Nop14-like family RXT2_N PF08595.11 KKK26055.1 - 0.71 9.9 14.9 1.6 8.8 14.9 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal NPR3 PF03666.13 KKK26055.1 - 0.86 8.3 11.9 1.3 7.8 11.9 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 SAGA-Tad1 PF12767.7 KKK26055.1 - 0.91 9.2 8.0 2 8.1 8.0 1.5 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Radial_spoke PF04712.12 KKK26055.1 - 1.3 7.9 16.4 2.4 7.0 16.4 1.4 1 0 0 1 1 1 0 Radial spokehead-like protein Paf1 PF03985.13 KKK26055.1 - 1.6 7.7 20.5 2.4 7.1 20.5 1.2 1 0 0 1 1 1 0 Paf1 Vfa1 PF08432.10 KKK26055.1 - 1.6 9.0 20.3 3.4 8.0 20.3 1.5 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 NOA36 PF06524.12 KKK26055.1 - 1.7 7.9 24.6 18 4.5 23.5 2.1 2 0 0 2 2 2 0 NOA36 protein Rrn6 PF10214.9 KKK26055.1 - 2 6.8 6.8 3.1 6.2 6.8 1.2 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Tim54 PF11711.8 KKK26055.1 - 2.1 7.0 11.5 3.3 6.4 11.5 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF4746 PF15928.5 KKK26055.1 - 2.5 7.4 24.0 4.7 6.5 24.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DNA_pol_phi PF04931.13 KKK26055.1 - 4 5.4 24.9 5.9 4.9 24.9 1.2 1 0 0 1 1 1 0 DNA polymerase phi Presenilin PF01080.17 KKK26055.1 - 4.5 5.9 12.2 6.9 5.3 12.2 1.2 1 0 0 1 1 1 0 Presenilin TFIIF_alpha PF05793.12 KKK26055.1 - 7.9 4.9 30.8 12 4.3 30.8 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF4820 PF16091.5 KKK26057.1 - 0.015 14.7 0.1 0.024 14.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) HCO3_cotransp PF00955.21 KKK26057.1 - 0.17 10.7 0.1 0.27 10.0 0.1 1.2 1 0 0 1 1 1 0 HCO3- transporter family DUF5034 PF16437.5 KKK26059.1 - 0.033 14.2 0.0 0.064 13.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5034) Sars6 PF12133.8 KKK26059.1 - 0.15 12.0 0.1 0.36 10.8 0.1 1.6 1 0 0 1 1 1 0 Open reading frame 6 from SARS coronavirus NDUFA12 PF05071.16 KKK26060.1 - 2.4e-13 50.7 4.0 5.7e-13 49.5 4.0 1.8 1 1 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 Microvir_J PF04726.13 KKK26061.1 - 0.47 10.5 3.9 0.93 9.5 3.9 1.5 1 0 0 1 1 1 0 Microvirus J protein Pyridoxal_deC PF00282.19 KKK26074.1 - 8.9e-73 245.2 0.0 1.1e-72 244.8 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain OKR_DC_1 PF01276.20 KKK26074.1 - 0.091 11.5 0.0 0.13 11.0 0.0 1.3 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain Phasin PF05597.11 KKK26075.1 - 0.15 12.0 0.5 0.38 10.7 0.5 1.7 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) NPV_P10 PF05531.12 KKK26075.1 - 0.17 12.4 0.2 0.43 11.1 0.2 1.7 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein MFS_1 PF07690.16 KKK26076.1 - 2.6e-31 108.9 37.9 4.1e-18 65.4 5.0 3.0 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KKK26076.1 - 6e-05 22.1 10.5 6e-05 22.1 10.5 3.1 2 1 0 2 2 2 1 Sugar (and other) transporter GCIP PF13324.6 KKK26077.1 - 0.07 12.7 0.1 0.1 12.2 0.1 1.2 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting DUF4551 PF15087.6 KKK26077.1 - 4.3 6.1 7.2 4.6 6.0 7.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Trypan_PARP PF05887.11 KKK26077.1 - 8.5 6.4 10.6 0.42 10.6 5.1 1.6 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Glyco_hydro_71 PF03659.14 KKK26078.1 - 1.1e-137 458.9 6.1 1.6e-137 458.4 6.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 Glyco_transf_28 PF03033.20 KKK26079.1 - 5.2e-18 65.4 0.1 3e-12 46.7 0.0 2.4 2 0 0 2 2 2 2 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 KKK26079.1 - 1.3e-05 24.2 0.0 2.3e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase ATG_C PF09333.11 KKK26079.1 - 3.1e-05 24.2 0.0 9.7e-05 22.6 0.0 1.8 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain Glyco_tran_28_C PF04101.16 KKK26079.1 - 0.016 15.2 0.0 0.03 14.3 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain AF-4 PF05110.13 KKK26079.1 - 8.5 4.3 9.2 12 3.8 9.2 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Annexin PF00191.20 KKK26080.1 - 2.9e-50 168.2 0.5 4.6e-19 68.3 0.0 3.4 3 0 0 3 3 3 3 Annexin B56 PF01603.20 KKK26082.1 - 2.1e-191 636.3 7.2 2.5e-191 636.1 7.2 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Sec7_N PF12783.7 KKK26082.1 - 0.00034 20.5 2.3 0.31 10.9 0.0 2.6 2 0 0 2 2 2 2 Guanine nucleotide exchange factor in Golgi transport N-terminal Asparaginase_2 PF01112.18 KKK26088.1 - 1e-49 169.2 0.9 1.5e-31 109.6 0.0 2.1 2 0 0 2 2 2 2 Asparaginase Actin PF00022.19 KKK26089.1 - 1.2e-87 294.2 0.0 4e-85 285.9 0.0 2.0 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 KKK26089.1 - 0.051 12.4 0.0 1.1 8.0 0.0 2.2 2 0 0 2 2 2 0 MreB/Mbl protein Cation_ATPase_C PF00689.21 KKK26114.1 - 5.8e-25 88.1 11.6 5.8e-25 88.1 11.6 2.2 2 1 0 2 2 2 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 KKK26114.1 - 4.2e-23 81.8 5.3 7.3e-14 51.7 0.0 2.7 2 0 0 2 2 2 2 E1-E2 ATPase Hydrolase PF00702.26 KKK26114.1 - 2.6e-18 67.1 0.2 4.9e-17 62.9 0.2 2.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KKK26114.1 - 2.2e-15 56.5 0.0 5.7e-15 55.2 0.0 1.7 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KKK26114.1 - 0.00039 20.2 0.1 0.016 15.0 0.2 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Na_Pi_cotrans PF02690.15 KKK26114.1 - 0.14 12.2 1.7 0.61 10.2 1.7 2.1 2 0 0 2 2 2 0 Na+/Pi-cotransporter BATS PF06968.13 KKK26115.1 - 1.5e-22 79.5 0.2 7.4e-22 77.3 0.0 2.2 2 1 0 2 2 2 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.21 KKK26115.1 - 7.2e-16 59.0 0.0 2.8e-14 53.8 0.0 2.7 3 0 0 3 3 3 1 Radical SAM superfamily P33MONOX PF15302.6 KKK26115.1 - 0.078 12.7 0.0 0.19 11.4 0.0 1.6 1 0 0 1 1 1 0 P33 mono-oxygenase Aminotran_3 PF00202.21 KKK26116.1 - 6.2e-37 127.2 0.0 1.6e-19 69.8 0.0 3.1 2 1 0 2 2 2 2 Aminotransferase class-III AAA_26 PF13500.6 KKK26116.1 - 1.1e-21 77.5 0.0 2.1e-21 76.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain Aminotran_1_2 PF00155.21 KKK26117.1 - 5.7e-38 131.0 0.0 6.7e-38 130.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KKK26117.1 - 0.013 14.1 0.0 0.017 13.7 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Aminotran_3 PF00202.21 KKK26117.1 - 0.027 13.1 0.0 0.036 12.7 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-III Glyco_hydro_3_C PF01915.22 KKK26118.1 - 2.7e-37 128.7 0.0 5.4e-37 127.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KKK26118.1 - 4.5e-35 121.5 0.0 6.9e-35 120.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Citrate_synt PF00285.21 KKK26119.1 - 4.8e-95 318.7 0.0 5.8e-95 318.4 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain ABC_tran PF00005.27 KKK26120.1 - 5.5e-47 159.7 0.0 1.6e-25 90.2 0.0 3.8 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KKK26120.1 - 5.5e-14 52.7 2.2 6.7e-05 22.8 0.0 4.3 3 1 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KKK26120.1 - 5.1e-11 42.4 0.3 0.0068 15.9 0.0 4.3 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain Chromo PF00385.24 KKK26120.1 - 1.6e-07 31.1 0.0 3.1e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain MMR_HSR1 PF01926.23 KKK26120.1 - 8.5e-07 29.1 0.0 0.019 15.0 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_23 PF13476.6 KKK26120.1 - 1e-06 29.4 0.0 0.054 14.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 KKK26120.1 - 4.9e-06 26.5 0.0 0.047 13.6 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 KKK26120.1 - 2.8e-05 23.8 3.4 0.11 12.3 0.5 2.9 3 0 0 3 3 3 2 P-loop containing region of AAA domain DUF87 PF01935.17 KKK26120.1 - 0.00026 21.2 1.3 0.27 11.3 0.1 3.9 4 1 0 4 4 3 1 Helicase HerA, central domain AAA_15 PF13175.6 KKK26120.1 - 0.00035 20.4 0.2 0.53 9.9 0.3 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA_13 PF13166.6 KKK26120.1 - 0.00039 19.2 0.0 0.013 14.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 KKK26120.1 - 0.00042 20.6 0.0 0.15 12.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KKK26120.1 - 0.00054 20.2 0.0 0.38 11.0 0.0 3.0 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.6 KKK26120.1 - 0.0014 18.8 0.0 2.5 8.4 0.0 3.3 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit RNA_helicase PF00910.22 KKK26120.1 - 0.0022 18.4 0.0 1.3 9.5 0.0 2.7 2 0 0 2 2 2 1 RNA helicase Dynamin_N PF00350.23 KKK26120.1 - 0.0027 17.8 0.2 0.21 11.6 0.0 3.0 2 1 0 2 2 2 1 Dynamin family AAA_24 PF13479.6 KKK26120.1 - 0.0039 16.9 0.2 0.45 10.2 0.2 2.5 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KKK26120.1 - 0.008 16.3 0.1 3 8.0 0.0 3.0 3 0 0 3 3 2 1 AAA domain NACHT PF05729.12 KKK26120.1 - 0.0096 15.8 2.9 0.46 10.4 0.0 2.9 3 0 0 3 3 2 1 NACHT domain MeaB PF03308.16 KKK26120.1 - 0.016 14.2 0.1 4.7 6.1 0.1 2.4 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 KKK26120.1 - 0.039 13.7 0.3 11 5.7 0.1 2.7 2 0 0 2 2 2 0 AAA domain MukB PF04310.12 KKK26120.1 - 0.062 13.1 0.0 9.5 6.0 0.0 2.4 2 0 0 2 2 2 0 MukB N-terminal PduV-EutP PF10662.9 KKK26120.1 - 0.069 12.9 0.1 4.6 7.0 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Roc PF08477.13 KKK26120.1 - 0.079 13.2 0.0 23 5.2 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase NB-ARC PF00931.22 KKK26120.1 - 0.094 11.9 1.0 0.68 9.1 0.0 2.7 3 0 0 3 3 3 0 NB-ARC domain Septin PF00735.18 KKK26120.1 - 0.095 12.0 0.0 14 4.9 0.0 2.3 2 0 0 2 2 2 0 Septin DUF815 PF05673.13 KKK26120.1 - 0.1 11.7 0.1 7.6 5.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA PF00004.29 KKK26120.1 - 0.11 12.9 0.0 5.3 7.5 0.0 3.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 KKK26120.1 - 0.13 12.3 0.6 22 5.0 0.0 2.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ALF PF03752.13 KKK26120.1 - 0.14 12.2 2.7 1.4 9.0 0.6 3.0 2 0 0 2 2 2 0 Short repeats of unknown function AAA_18 PF13238.6 KKK26120.1 - 0.14 12.7 0.0 25 5.4 0.0 2.9 3 0 0 3 3 2 0 AAA domain AAA_27 PF13514.6 KKK26120.1 - 0.17 11.5 1.6 9.8 5.7 0.0 2.7 3 0 0 3 3 2 0 AAA domain HEAT PF02985.22 KKK26120.1 - 0.2 12.0 1.9 52 4.5 0.0 4.5 4 0 0 4 4 4 0 HEAT repeat zf-RING_2 PF13639.6 KKK26121.1 - 1.1e-06 28.8 3.6 0.00014 22.1 1.3 2.5 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 KKK26121.1 - 2e-06 28.0 1.5 9.5e-06 25.8 0.4 2.4 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KKK26121.1 - 4.9e-05 23.3 1.9 0.00021 21.3 0.6 2.2 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger DNA_pol_phi PF04931.13 KKK26121.1 - 0.0021 16.3 17.4 0.0028 15.9 17.4 1.1 1 0 0 1 1 1 1 DNA polymerase phi PHD PF00628.29 KKK26121.1 - 0.012 15.5 1.1 0.029 14.3 1.1 1.7 1 0 0 1 1 1 0 PHD-finger FANCL_C PF11793.8 KKK26121.1 - 0.044 14.0 4.8 0.3 11.3 2.1 2.5 2 1 0 2 2 2 0 FANCL C-terminal domain PHD_2 PF13831.6 KKK26121.1 - 0.11 12.1 2.1 0.23 11.1 2.1 1.6 1 0 0 1 1 1 0 PHD-finger zf-C3HC4_4 PF15227.6 KKK26121.1 - 0.22 11.7 8.2 0.092 12.9 2.4 2.3 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING RINGv PF12906.7 KKK26121.1 - 0.24 11.5 5.8 0.086 13.0 2.8 1.8 2 0 0 2 2 1 0 RING-variant domain Cwf_Cwc_15 PF04889.12 KKK26121.1 - 0.49 10.1 21.1 0.12 12.1 17.8 1.6 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein zf-C3HC4 PF00097.25 KKK26121.1 - 0.76 9.7 9.9 0.13 12.2 1.5 2.5 3 0 0 3 3 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 KKK26121.1 - 0.92 9.3 6.1 0.41 10.5 1.7 2.5 3 0 0 3 3 2 0 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.6 KKK26121.1 - 0.98 9.5 4.7 9.7 6.3 0.3 2.7 2 0 0 2 2 2 0 RING-type zinc-finger Nucleo_P87 PF07267.11 KKK26121.1 - 1.1 8.1 9.0 0.89 8.3 7.9 1.3 1 1 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 zf-RING-like PF08746.11 KKK26121.1 - 1.3 9.4 5.2 0.24 11.7 1.4 1.8 2 0 0 2 2 1 0 RING-like domain FYDLN_acid PF09538.10 KKK26121.1 - 1.4 9.6 21.3 0.26 12.0 14.6 2.7 3 0 0 3 3 2 0 Protein of unknown function (FYDLN_acid) TRAP_alpha PF03896.16 KKK26121.1 - 2.4 7.3 5.8 3.6 6.7 5.8 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit zf-C3HC4_2 PF13923.6 KKK26121.1 - 3.3 7.6 8.8 1.4 8.8 1.5 2.7 3 0 0 3 3 2 0 Zinc finger, C3HC4 type (RING finger) PTPRCAP PF15713.5 KKK26121.1 - 4.1 7.7 12.7 7.9 6.8 12.7 1.4 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Prok-RING_4 PF14447.6 KKK26121.1 - 5.9 6.8 7.5 3 7.8 1.2 2.7 3 0 0 3 3 3 0 Prokaryotic RING finger family 4 NOA36 PF06524.12 KKK26121.1 - 6.8 5.9 27.1 0.72 9.1 22.9 1.4 2 0 0 2 2 2 0 NOA36 protein TFB6 PF17110.5 KKK26121.1 - 7.5 6.3 8.2 14 5.4 8.2 1.4 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH zf-RING_5 PF14634.6 KKK26121.1 - 8.7 6.4 8.5 0.42 10.6 0.5 2.4 3 0 0 3 3 2 0 zinc-RING finger domain ANAPC15 PF15243.6 KKK26121.1 - 9.3 6.7 19.3 22 5.5 19.3 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 Amidoligase_2 PF12224.8 KKK26137.1 - 5.8e-07 29.4 0.0 6.7e-07 29.2 0.0 1.1 1 0 0 1 1 1 1 Putative amidoligase enzyme Pkinase PF00069.25 KKK26138.1 - 9.3e-35 120.3 0.0 2.8e-17 62.9 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KKK26138.1 - 3.6e-16 59.2 0.0 3e-14 52.9 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase DUF3128 PF11326.8 KKK26139.1 - 2.1e-27 95.3 3.0 3.6e-27 94.5 3.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) Ndc1_Nup PF09531.10 KKK26139.1 - 0.85 8.2 3.1 0.85 8.2 3.1 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup RNA12 PF10443.9 KKK26140.1 - 1.3e-172 574.5 0.0 6e-171 569.1 0.0 2.2 1 1 0 1 1 1 1 RNA12 protein p450 PF00067.22 KKK26140.1 - 4.3e-20 71.9 0.0 1.7e-19 69.9 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 ATPase_2 PF01637.18 KKK26140.1 - 1.2e-05 25.4 0.0 2.5e-05 24.3 0.0 1.6 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea RRM_1 PF00076.22 KKK26140.1 - 5.5e-05 22.9 0.0 0.00024 20.8 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAA_16 PF13191.6 KKK26140.1 - 0.006 17.0 0.0 0.02 15.3 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain DUF2487 PF10673.9 KKK26140.1 - 0.029 14.4 0.0 0.076 13.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2487) Peptidase_C14 PF00656.22 KKK26141.1 - 1.4e-05 25.2 0.0 1.7e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Caspase domain Raptor_N PF14538.6 KKK26141.1 - 0.0038 17.2 0.1 0.024 14.6 0.1 2.4 2 1 0 2 2 2 1 Raptor N-terminal CASPase like domain GGACT PF06094.12 KKK26142.1 - 2.4e-11 44.3 0.0 2.8e-11 44.1 0.0 1.1 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like Apc15p PF05841.11 KKK26143.1 - 1.2e-15 58.4 0.6 2.7e-15 57.2 0.0 1.8 2 0 0 2 2 2 1 Apc15p protein GXGXG PF01493.19 KKK26144.1 - 2.1e-86 288.4 2.6 3.3e-86 287.8 2.6 1.3 1 0 0 1 1 1 1 GXGXG motif Pyr_redox_2 PF07992.14 KKK26144.1 - 7.2e-27 94.4 0.2 6.2e-26 91.3 0.2 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_20 PF14691.6 KKK26144.1 - 1.2e-21 76.6 0.1 2e-21 75.9 0.1 1.4 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox_3 PF13738.6 KKK26144.1 - 9.4e-10 38.2 0.6 0.0047 16.2 0.0 3.7 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KKK26144.1 - 3.5e-09 36.7 0.0 1.3e-08 34.9 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KKK26144.1 - 5.9e-09 36.4 0.2 2.8e-05 24.6 0.1 3.2 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KKK26144.1 - 1.9e-08 34.3 2.0 0.0011 18.7 0.7 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Amino_oxidase PF01593.24 KKK26144.1 - 1.6e-07 31.0 0.2 3.1e-07 30.1 0.2 1.4 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 KKK26144.1 - 6e-06 25.6 0.3 0.00016 20.9 0.1 2.5 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.7 KKK26144.1 - 1.4e-05 24.7 0.1 1.4e-05 24.7 0.1 1.6 2 0 0 2 2 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KKK26144.1 - 4.2e-05 22.4 0.2 4.2e-05 22.4 0.2 1.9 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_7 PF13241.6 KKK26144.1 - 0.00013 22.3 0.1 0.91 10.0 0.0 2.6 2 0 0 2 2 2 2 Putative NAD(P)-binding AlaDh_PNT_C PF01262.21 KKK26144.1 - 0.00033 20.0 0.2 0.16 11.2 0.1 2.3 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 KKK26144.1 - 0.00038 19.8 0.0 0.0011 18.4 0.0 1.7 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 KKK26144.1 - 0.011 14.8 0.2 0.19 10.7 0.2 2.3 2 0 0 2 2 2 0 Lycopene cyclase protein GIDA PF01134.22 KKK26144.1 - 0.012 14.7 2.1 0.028 13.5 0.1 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A FMO-like PF00743.19 KKK26144.1 - 0.012 14.1 0.0 0.78 8.1 0.0 2.2 2 0 0 2 2 2 0 Flavin-binding monooxygenase-like Thi4 PF01946.17 KKK26144.1 - 0.014 14.6 0.1 0.014 14.6 0.1 1.6 2 0 0 2 2 1 0 Thi4 family F420_oxidored PF03807.17 KKK26144.1 - 0.025 15.2 0.1 0.72 10.5 0.1 2.7 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 KKK26144.1 - 0.031 13.6 0.1 0.16 11.3 0.0 2.0 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.16 KKK26144.1 - 0.032 13.9 0.1 0.39 10.3 0.1 2.3 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA YjeF_N PF03853.15 KKK26144.1 - 0.071 13.0 0.0 0.98 9.3 0.0 2.3 2 0 0 2 2 2 0 YjeF-related protein N-terminus Shikimate_DH PF01488.20 KKK26144.1 - 0.081 13.0 0.0 18 5.4 0.0 3.0 3 1 1 4 4 3 0 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.6 KKK26144.1 - 0.087 12.8 0.7 0.32 11.0 0.1 2.3 3 1 1 4 4 2 0 FAD-NAD(P)-binding AdoHcyase_NAD PF00670.21 KKK26144.1 - 0.13 12.3 2.6 12 5.9 0.1 2.9 3 0 0 3 3 3 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 KKK26144.1 - 0.16 11.9 0.0 0.33 10.9 0.0 1.6 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus IlvN PF07991.12 KKK26144.1 - 0.27 10.8 1.6 0.32 10.6 0.1 1.8 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain 3HCDH_N PF02737.18 KKK26144.1 - 5 7.0 4.7 0.62 9.9 0.2 1.8 2 0 0 2 2 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GATase_2 PF00310.21 KKK26145.1 - 4.3e-182 605.5 0.0 5.5e-182 605.2 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_synthase PF01645.17 KKK26145.1 - 4.6e-146 486.7 0.0 6.8e-146 486.1 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase Glu_syn_central PF04898.14 KKK26145.1 - 9.7e-114 379.6 0.0 1.5e-112 375.6 0.0 2.1 2 0 0 2 2 2 1 Glutamate synthase central domain FMN_dh PF01070.18 KKK26145.1 - 0.0037 16.3 1.2 0.0074 15.4 1.2 1.4 1 0 0 1 1 1 1 FMN-dependent dehydrogenase LMBR1 PF04791.16 KKK26150.1 - 1.8e-133 446.1 4.3 2.5e-133 445.7 4.3 1.2 1 0 0 1 1 1 1 LMBR1-like membrane protein BAG PF02179.16 KKK26150.1 - 4.3e-13 49.5 0.0 7.8e-13 48.7 0.0 1.5 1 0 0 1 1 1 1 BAG domain ubiquitin PF00240.23 KKK26150.1 - 0.00035 20.3 0.0 0.00065 19.4 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family FUSC PF04632.12 KKK26150.1 - 0.0048 15.5 0.8 0.0048 15.5 0.8 2.3 2 0 0 2 2 2 2 Fusaric acid resistance protein family DUF2142 PF09913.9 KKK26150.1 - 0.46 9.3 12.1 1.7 7.4 12.1 2.0 1 1 0 1 1 1 0 Predicted membrane protein (DUF2142) Chalcone_2 PF16035.5 KKK26151.1 - 4.6e-79 264.9 0.0 6.1e-79 264.5 0.0 1.2 1 0 0 1 1 1 1 Chalcone isomerase like Chalcone_3 PF16036.5 KKK26151.1 - 0.00052 20.2 0.0 0.0036 17.4 0.0 2.1 2 0 0 2 2 2 1 Chalcone isomerase-like Glutaredoxin PF00462.24 KKK26152.1 - 2.1e-21 75.9 0.0 3e-21 75.4 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_2 PF13098.6 KKK26152.1 - 0.00087 19.7 0.0 0.0014 19.1 0.0 1.3 1 1 0 1 1 1 1 Thioredoxin-like domain DUF836 PF05768.14 KKK26152.1 - 0.0011 19.4 0.0 0.0013 19.1 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin PF00085.20 KKK26152.1 - 0.014 15.4 0.0 0.015 15.3 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin TraF PF13728.6 KKK26152.1 - 0.041 13.7 0.0 0.044 13.6 0.0 1.2 1 0 0 1 1 1 0 F plasmid transfer operon protein SRP14 PF02290.15 KKK26152.1 - 0.06 13.7 0.0 0.32 11.4 0.0 1.9 2 0 0 2 2 2 0 Signal recognition particle 14kD protein GST_N_3 PF13417.6 KKK26152.1 - 0.078 13.4 0.0 0.12 12.7 0.0 1.4 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain DSBA PF01323.20 KKK26152.1 - 0.08 12.7 0.3 0.34 10.6 0.2 1.8 1 1 1 2 2 2 0 DSBA-like thioredoxin domain Med15_fungi PF05397.12 KKK26153.1 - 4.7e-33 113.8 0.1 4.7e-33 113.8 0.1 6.9 6 1 0 6 6 6 1 Mediator complex subunit 15 KIX_2 PF16987.5 KKK26153.1 - 1.9e-10 40.6 0.7 1.9e-10 40.6 0.7 4.3 4 1 0 4 4 4 1 KIX domain SID-1_RNA_chan PF13965.6 KKK26153.1 - 9.8 4.5 5.7 20 3.4 5.7 1.4 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 EamA PF00892.20 KKK26154.1 - 4.4e-10 39.9 24.9 4.8e-05 23.5 5.5 2.6 2 0 0 2 2 2 2 EamA-like transporter family Nuc_sug_transp PF04142.15 KKK26154.1 - 1e-09 38.0 1.0 1.8e-09 37.2 1.0 1.4 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.11 KKK26154.1 - 3.3e-05 23.3 8.1 8.3e-05 21.9 8.3 1.5 2 0 0 2 2 2 1 UAA transporter family TPT PF03151.16 KKK26154.1 - 9.4e-05 21.9 3.2 0.00044 19.7 0.1 2.4 2 1 0 2 2 2 1 Triose-phosphate Transporter family Proton_antipo_C PF01010.19 KKK26154.1 - 0.0063 16.2 0.1 0.011 15.3 0.1 1.3 1 0 0 1 1 1 1 NADH-dehyrogenase subunit F, TMs, (complex I) C-terminus DUF3290 PF11694.8 KKK26154.1 - 0.35 10.8 2.1 0.41 10.6 0.0 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3290) PALP PF00291.25 KKK26157.1 - 2.6e-53 181.4 0.3 3e-53 181.2 0.3 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme ADH_zinc_N PF00107.26 KKK26157.1 - 0.017 15.1 0.1 0.13 12.3 0.0 2.5 2 0 0 2 2 2 0 Zinc-binding dehydrogenase GTP_EFTU_D3 PF03143.17 KKK26158.1 - 1.3e-41 141.4 0.0 3e-41 140.3 0.0 1.6 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 KKK26158.1 - 1.1e-13 51.3 1.3 1.1e-13 51.3 1.3 1.6 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.6 KKK26158.1 - 0.0095 15.8 0.8 0.024 14.5 0.8 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 4 Semialdhyde_dhC PF02774.18 KKK26158.1 - 0.033 14.2 0.4 0.26 11.4 0.1 2.3 1 1 1 2 2 2 0 Semialdehyde dehydrogenase, dimerisation domain TIP49 PF06068.13 KKK26159.1 - 4.6e-167 555.6 0.0 5.5e-167 555.4 0.0 1.0 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 KKK26159.1 - 1e-20 73.6 0.0 4e-20 71.7 0.0 2.0 2 0 0 2 2 2 1 TIP49 AAA-lid domain AAA PF00004.29 KKK26159.1 - 3.9e-11 43.5 0.2 4.2e-07 30.4 0.1 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KKK26159.1 - 1.5e-10 41.1 0.1 5.7e-07 29.4 0.0 2.3 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KKK26159.1 - 1.8e-05 25.0 0.1 0.088 13.1 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KKK26159.1 - 0.00015 22.2 0.1 0.0023 18.4 0.1 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.6 KKK26159.1 - 0.00016 22.0 0.8 0.065 13.6 0.3 2.3 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 KKK26159.1 - 0.0008 19.4 0.2 0.19 11.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 KKK26159.1 - 0.00087 19.6 0.1 0.002 18.4 0.1 1.6 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 KKK26159.1 - 0.0013 18.4 0.1 1.1 8.9 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain Zeta_toxin PF06414.12 KKK26159.1 - 0.0063 15.8 0.3 0.016 14.5 0.3 1.6 1 0 0 1 1 1 1 Zeta toxin AAA_25 PF13481.6 KKK26159.1 - 0.0088 15.6 0.1 0.02 14.5 0.1 1.5 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 KKK26159.1 - 0.012 15.0 0.1 0.57 9.5 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI DnaB_C PF03796.15 KKK26159.1 - 0.05 12.9 0.0 0.11 11.8 0.0 1.5 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain AAA_14 PF13173.6 KKK26159.1 - 0.051 13.6 0.0 0.78 9.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 KKK26159.1 - 0.06 13.1 0.1 0.12 12.1 0.1 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_18 PF13238.6 KKK26159.1 - 0.069 13.7 0.1 0.3 11.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 KKK26159.1 - 0.072 12.3 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ATPase PF06745.13 KKK26159.1 - 0.095 12.0 2.0 0.16 11.3 0.1 2.2 3 0 0 3 3 3 0 KaiC AAA_30 PF13604.6 KKK26159.1 - 0.1 12.3 0.2 1.5 8.5 0.1 2.3 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KKK26159.1 - 0.12 11.9 0.2 0.44 10.0 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region Amino_oxidase PF01593.24 KKK26160.1 - 2.5e-13 50.2 0.0 3.9e-13 49.5 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KKK26160.1 - 3.5e-10 40.0 0.0 6.6e-10 39.1 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KKK26160.1 - 0.00052 20.0 0.0 0.37 10.8 0.0 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding DAO PF01266.24 KKK26160.1 - 0.0016 18.1 0.1 0.0047 16.6 0.1 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KKK26160.1 - 0.0018 17.5 0.0 0.033 13.4 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KKK26160.1 - 0.0076 16.8 0.1 0.14 12.8 0.1 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KKK26160.1 - 0.16 10.7 0.0 12 4.5 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein FAD_oxidored PF12831.7 KKK26160.1 - 0.25 10.6 0.0 0.36 10.1 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase An_peroxidase PF03098.15 KKK26161.1 - 1.8e-37 129.1 0.0 4.3e-28 98.2 0.0 3.2 1 1 1 2 2 2 2 Animal haem peroxidase p450 PF00067.22 KKK26161.1 - 1.3e-09 37.3 0.0 1.2e-08 34.2 0.0 2.0 2 0 0 2 2 2 1 Cytochrome P450 Steroid_dh PF02544.16 KKK26162.1 - 3.2e-31 108.3 0.2 4.4e-31 107.9 0.2 1.2 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 KKK26162.1 - 5.8e-05 22.7 0.3 8.6e-05 22.2 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.13 KKK26162.1 - 0.014 15.8 1.3 0.02 15.3 0.2 1.8 2 0 0 2 2 2 0 Phospholipid methyltransferase Glyco_transf_34 PF05637.12 KKK26163.1 - 2.8e-62 210.6 0.0 3.5e-62 210.2 0.0 1.1 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Ribosomal_L28 PF00830.19 KKK26164.1 - 3.1e-18 65.7 1.1 6.7e-18 64.6 1.1 1.6 1 0 0 1 1 1 1 Ribosomal L28 family Bromodomain PF00439.25 KKK26165.1 - 2.3e-36 123.7 1.7 5.6e-18 64.8 0.2 2.5 2 0 0 2 2 2 2 Bromodomain BET PF17035.5 KKK26165.1 - 6.6e-21 74.3 2.1 1.8e-19 69.7 0.9 2.6 2 0 0 2 2 2 1 Bromodomain extra-terminal - transcription regulation CDC45 PF02724.14 KKK26165.1 - 0.2 9.9 12.8 0.34 9.2 12.8 1.3 1 0 0 1 1 1 0 CDC45-like protein DUF3573 PF12097.8 KKK26165.1 - 2 7.2 3.1 3.1 6.5 3.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) HAUS4 PF14735.6 KKK26166.1 - 0.006 16.3 1.9 0.021 14.6 1.9 1.9 1 1 0 1 1 1 1 HAUS augmin-like complex subunit 4 Ku_C PF03730.14 KKK26166.1 - 0.049 14.3 1.4 2.4 8.9 0.4 3.7 3 1 1 4 4 4 0 Ku70/Ku80 C-terminal arm DinB_2 PF12867.7 KKK26166.1 - 1.2 9.7 9.1 5.9 7.4 0.7 2.8 2 1 1 3 3 3 0 DinB superfamily ANAPC4_WD40 PF12894.7 KKK26167.1 - 4.6e-07 30.0 0.0 0.23 11.8 0.0 3.6 3 0 0 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KKK26167.1 - 4.9e-07 30.3 4.4 0.00072 20.3 0.0 5.6 6 0 0 6 6 6 1 WD domain, G-beta repeat Utp12 PF04003.12 KKK26168.1 - 1.9e-21 76.4 0.0 3.9e-21 75.4 0.0 1.6 1 0 0 1 1 1 1 Dip2/Utp12 Family AKAP7_NLS PF10469.9 KKK26169.1 - 2e-13 50.7 0.0 7.1e-13 48.9 0.0 1.9 1 1 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain Sec6 PF06046.13 KKK26170.1 - 2.2e-168 561.2 3.3 3.3e-168 560.6 3.3 1.3 1 0 0 1 1 1 1 Exocyst complex component Sec6 Vps53_N PF04100.12 KKK26170.1 - 0.001 18.1 12.6 0.0022 17.0 3.2 2.3 2 0 0 2 2 2 2 Vps53-like, N-terminal HEAT_2 PF13646.6 KKK26170.1 - 0.038 14.4 0.7 0.33 11.4 0.1 2.9 3 0 0 3 3 3 0 HEAT repeats DUF4972 PF16342.5 KKK26170.1 - 0.057 13.1 1.1 0.59 9.8 0.2 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4972) Dynactin_p22 PF07426.11 KKK26170.1 - 0.2 11.5 4.8 1.5 8.6 3.9 2.7 2 1 0 2 2 2 0 Dynactin subunit p22 BORCS8 PF10167.9 KKK26170.1 - 0.37 10.8 1.5 1.5 8.8 0.3 2.3 2 0 0 2 2 2 0 BLOC-1-related complex sub-unit 8 NPV_P10 PF05531.12 KKK26170.1 - 0.53 10.8 3.5 12 6.4 1.2 3.0 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Spc7 PF08317.11 KKK26170.1 - 0.94 8.3 7.7 2.2 7.1 7.7 1.6 1 0 0 1 1 1 0 Spc7 kinetochore protein zf-CSL PF05207.13 KKK26171.1 - 5.2e-23 80.5 0.2 6.2e-23 80.3 0.2 1.1 1 0 0 1 1 1 1 CSL zinc finger Prok-RING_1 PF14446.6 KKK26171.1 - 0.28 11.1 3.0 0.56 10.2 3.0 1.5 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 Frataxin_Cyay PF01491.16 KKK26172.1 - 1.1e-36 125.2 0.0 1.6e-36 124.7 0.0 1.2 1 0 0 1 1 1 1 Frataxin-like domain GKAP PF03359.13 KKK26172.1 - 0.0028 17.3 0.1 0.0045 16.6 0.1 1.3 1 0 0 1 1 1 1 Guanylate-kinase-associated protein (GKAP) protein Pyridoxal_deC PF00282.19 KKK26173.1 - 6e-13 48.3 0.0 5.1e-07 28.7 0.0 2.2 1 1 0 2 2 2 2 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 KKK26173.1 - 0.033 13.1 0.0 0.15 11.0 0.0 1.8 2 0 0 2 2 2 0 Aminotransferase class-V Aminotran_1_2 PF00155.21 KKK26173.1 - 0.14 11.3 0.0 0.23 10.6 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II HMGL-like PF00682.19 KKK26174.1 - 1.8e-79 267.0 0.2 2.5e-79 266.6 0.2 1.2 1 0 0 1 1 1 1 HMGL-like PPTA PF01239.22 KKK26175.1 - 8.7e-39 130.2 14.5 4.1e-08 32.7 0.1 5.4 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat DUF5072 PF16807.5 KKK26175.1 - 0.051 13.6 0.1 0.48 10.5 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5072) RabGAP-TBC PF00566.18 KKK26176.1 - 4.5e-54 183.4 0.1 2.2e-53 181.1 0.1 2.1 1 1 0 1 1 1 1 Rab-GTPase-TBC domain Fibin PF15819.5 KKK26176.1 - 1.2 8.9 7.3 2.4 7.9 0.1 2.4 2 0 0 2 2 2 0 Fin bud initiation factor homologue Med9 PF07544.13 KKK26176.1 - 3.7 7.7 8.8 0.64 10.2 0.4 3.3 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Asp-B-Hydro_N PF05279.11 KKK26176.1 - 7.5 6.5 17.8 1.5 8.9 10.4 2.2 2 0 0 2 2 2 0 Aspartyl beta-hydroxylase N-terminal region DUF1664 PF07889.12 KKK26176.1 - 7.6 6.6 11.6 3.6 7.6 8.6 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Fez1 PF06818.15 KKK26176.1 - 8.7 6.7 22.4 0.62 10.5 14.7 2.3 2 0 0 2 2 2 0 Fez1 DUF1741 PF08427.10 KKK26177.1 - 1e-91 306.7 0.3 2.3e-91 305.6 0.1 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF1741) Fe-S_biosyn PF01521.20 KKK26178.1 - 1.2e-19 70.5 0.0 1.6e-19 70.1 0.0 1.2 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis DUF2407_C PF13373.6 KKK26179.1 - 9.7e-43 145.7 0.1 1.7e-42 144.9 0.1 1.4 1 0 0 1 1 1 1 DUF2407 C-terminal domain DUF2407 PF10302.9 KKK26179.1 - 3.7e-36 123.9 0.1 1.7e-35 121.7 0.0 1.9 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.23 KKK26179.1 - 0.00051 19.8 0.0 0.00083 19.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family V-SNARE PF05008.15 KKK26180.1 - 1.2e-21 76.9 6.7 1.2e-21 76.9 6.7 1.9 2 0 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.8 KKK26180.1 - 2.2e-18 66.3 3.7 2.2e-18 66.3 3.7 2.8 3 1 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus Prominin PF05478.11 KKK26180.1 - 0.0086 14.1 3.2 0.011 13.7 3.2 1.0 1 0 0 1 1 1 1 Prominin Thump_like PF18096.1 KKK26180.1 - 0.031 14.2 0.0 0.061 13.3 0.0 1.4 1 0 0 1 1 1 0 THUMP domain-like Vps23_core PF09454.10 KKK26180.1 - 0.068 13.1 0.2 0.61 10.1 0.0 2.2 2 0 0 2 2 2 0 Vps23 core domain TBCA PF02970.16 KKK26180.1 - 0.13 12.7 10.7 9.1 6.7 1.8 3.1 2 1 1 3 3 3 0 Tubulin binding cofactor A H-kinase_dim PF02895.14 KKK26180.1 - 1.6 9.2 5.9 10 6.6 1.4 2.4 2 0 0 2 2 2 0 Signal transducing histidine kinase, homodimeric domain Exonuc_VII_L PF02601.15 KKK26180.1 - 6.1 6.3 13.7 18 4.8 13.7 1.7 1 1 0 1 1 1 0 Exonuclease VII, large subunit DUF349 PF03993.12 KKK26180.1 - 6.6 7.1 7.0 2.4 8.5 0.5 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF349) zf-C4H2 PF10146.9 KKK26180.1 - 9.5 6.5 8.9 55 4.0 8.9 2.0 1 1 0 1 1 1 0 Zinc finger-containing protein Dabb PF07876.12 KKK26181.1 - 3.3e-12 46.9 0.0 3.6e-12 46.7 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Ctf8 PF09696.10 KKK26182.1 - 9.5e-28 97.3 0.0 1.1e-27 97.1 0.0 1.1 1 0 0 1 1 1 1 Ctf8 Cnl2_NKP2 PF09447.10 KKK26183.1 - 4.8e-27 93.9 1.2 9.1e-27 93.0 1.2 1.5 1 0 0 1 1 1 1 Cnl2/NKP2 family protein APG6_N PF17675.1 KKK26183.1 - 0.012 16.2 0.2 0.031 14.8 0.1 1.7 1 1 0 1 1 1 0 Apg6 coiled-coil region MRG PF05712.13 KKK26184.1 - 4e-58 196.0 0.4 6.3e-58 195.4 0.4 1.3 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.8 KKK26184.1 - 4.7e-10 39.2 4.1 8.4e-10 38.4 3.2 2.0 2 0 0 2 2 2 1 RNA binding activity-knot of a chromodomain Chromo PF00385.24 KKK26184.1 - 0.0026 17.6 1.1 0.0088 15.9 1.1 1.9 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain PWWP PF00855.17 KKK26184.1 - 0.028 14.8 1.1 0.042 14.2 0.1 1.8 2 0 0 2 2 2 0 PWWP domain Aminotran_1_2 PF00155.21 KKK26185.1 - 2.3e-91 306.7 0.0 2.6e-91 306.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II APH PF01636.23 KKK26186.1 - 0.00035 20.6 0.0 0.00042 20.3 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF155 PF02582.14 KKK26187.1 - 1.1e-53 182.0 0.0 1.7e-53 181.4 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Occludin_ELL PF07303.13 KKK26188.1 - 0.33 11.7 4.7 0.45 11.3 1.2 2.5 2 0 0 2 2 2 0 Occludin homology domain Yuri_gagarin PF15934.5 KKK26188.1 - 1 9.2 5.0 0.18 11.6 0.6 1.9 2 0 0 2 2 2 0 Yuri gagarin DUF4448 PF14610.6 KKK26190.1 - 6.4e-39 133.7 0.0 9.9e-39 133.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) stn_TNFRSF12A PF12191.8 KKK26190.1 - 0.064 13.5 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain LapA_dom PF06305.11 KKK26190.1 - 0.15 11.9 0.8 0.25 11.2 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain SART-1 PF03343.13 KKK26191.1 - 5.2e-194 646.4 63.4 6e-194 646.2 63.4 1.0 1 0 0 1 1 1 1 SART-1 family PTH2 PF01981.16 KKK26192.1 - 3.3e-42 143.5 0.5 5.1e-42 142.9 0.5 1.3 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 tRNA_synt_1c_R2 PF04557.15 KKK26192.1 - 0.038 14.9 1.3 0.52 11.3 0.8 2.2 2 0 0 2 2 2 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 AIPR PF10592.9 KKK26192.1 - 0.11 12.1 0.1 0.14 11.7 0.1 1.1 1 0 0 1 1 1 0 AIPR protein HA1 PF18239.1 KKK26192.1 - 0.16 11.8 0.0 0.33 10.8 0.0 1.5 1 0 0 1 1 1 0 Hemagglutinin I RRM_1 PF00076.22 KKK26193.1 - 1.9e-45 152.5 0.0 7e-17 61.0 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KKK26193.1 - 6.2e-06 26.1 0.1 0.0014 18.5 0.0 3.0 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 KKK26193.1 - 0.00011 22.1 0.0 0.0011 18.9 0.0 2.3 3 0 0 3 3 3 1 RNA binding motif RRM_occluded PF16842.5 KKK26193.1 - 0.00016 21.4 0.0 0.053 13.4 0.0 2.7 3 0 0 3 3 3 1 Occluded RNA-recognition motif RRM_7 PF16367.5 KKK26193.1 - 0.00038 20.5 0.1 0.048 13.8 0.0 3.0 3 1 0 3 3 3 1 RNA recognition motif RRM_5 PF13893.6 KKK26193.1 - 0.01 15.4 0.0 0.065 12.8 0.0 2.2 3 0 0 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 KKK26193.1 - 0.074 13.3 0.1 14 5.9 0.0 3.6 3 1 1 4 4 4 0 Cytosolic domain of 10TM putative phosphate transporter TPR_1 PF00515.28 KKK26194.1 - 2.8e-27 93.4 4.3 0.00044 20.0 0.3 9.9 10 0 0 10 10 10 6 Tetratricopeptide repeat ANAPC3 PF12895.7 KKK26194.1 - 1.1e-26 92.8 15.5 1.1e-22 80.0 0.9 6.0 6 0 0 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 KKK26194.1 - 9.1e-26 87.9 15.9 0.0085 16.1 0.2 10.6 11 0 0 11 11 10 7 Tetratricopeptide repeat TPR_19 PF14559.6 KKK26194.1 - 3.8e-21 75.4 12.4 0.00032 21.1 0.1 7.4 6 2 2 8 8 7 4 Tetratricopeptide repeat TPR_12 PF13424.6 KKK26194.1 - 3.8e-17 62.3 27.0 2.2e-08 34.3 0.2 9.9 7 3 2 9 9 9 3 Tetratricopeptide repeat TPR_8 PF13181.6 KKK26194.1 - 1.5e-14 52.9 4.9 0.53 10.6 0.1 8.8 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_16 PF13432.6 KKK26194.1 - 3.5e-12 46.8 27.4 0.54 10.9 1.0 8.4 7 2 2 9 9 9 7 Tetratricopeptide repeat TPR_14 PF13428.6 KKK26194.1 - 2.7e-11 43.3 23.2 2.4 9.2 0.3 10.2 7 3 4 11 11 10 2 Tetratricopeptide repeat TPR_11 PF13414.6 KKK26194.1 - 2.4e-10 39.9 0.5 0.37 10.5 0.1 8.1 8 1 1 9 9 9 2 TPR repeat TPR_10 PF13374.6 KKK26194.1 - 4e-09 36.0 17.5 0.00033 20.4 0.0 7.6 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_6 PF13174.6 KKK26194.1 - 2.7e-07 30.8 8.9 1.4 9.7 0.2 7.8 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_7 PF13176.6 KKK26194.1 - 2.9e-07 30.1 19.0 0.79 9.9 0.0 8.8 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_17 PF13431.6 KKK26194.1 - 1.9e-05 24.7 7.4 5 7.7 0.0 7.8 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_4 PF07721.14 KKK26194.1 - 0.00016 22.0 24.9 0.022 15.4 0.2 8.5 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_21 PF09976.9 KKK26194.1 - 0.0089 15.8 1.7 11 5.7 0.1 4.7 5 1 0 5 5 5 0 Tetratricopeptide repeat-like domain SRP_TPR_like PF17004.5 KKK26194.1 - 0.11 12.6 0.1 1.7 8.7 0.0 2.8 2 0 0 2 2 2 0 Putative TPR-like repeat TPR_MalT PF17874.1 KKK26194.1 - 1.3 8.4 15.1 0.015 14.7 2.4 3.6 4 2 0 4 4 4 0 MalT-like TPR region FAT PF02259.23 KKK26195.1 - 1e-72 245.3 10.9 2.3e-72 244.1 10.9 1.6 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.27 KKK26195.1 - 1.3e-35 123.5 0.7 3.3e-35 122.1 0.1 2.1 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 KKK26195.1 - 1.7e-05 24.5 0.1 5e-05 23.0 0.1 1.9 1 0 0 1 1 1 1 FATC domain TPR_2 PF07719.17 KKK26195.1 - 1.7 9.0 3.5 19 5.7 0.2 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF572 PF04502.13 KKK26196.1 - 1.7e-70 238.3 18.6 2e-70 238.1 18.6 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) DUF4542 PF15075.6 KKK26196.1 - 0.024 15.0 0.5 0.12 12.7 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4542) Zn_ribbon_SprT PF17283.2 KKK26196.1 - 0.2 11.6 2.1 0.39 10.7 2.1 1.5 1 0 0 1 1 1 0 SprT-like zinc ribbon domain zf-ACC PF17848.1 KKK26196.1 - 0.32 11.1 3.0 0.9 9.7 0.5 2.4 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain YjbH PF06082.11 KKK26196.1 - 3.2 6.4 6.7 3.8 6.2 6.7 1.1 1 0 0 1 1 1 0 Exopolysaccharide biosynthesis protein YbjH Gln-synt_C PF00120.24 KKK26197.1 - 3.3e-15 56.0 0.0 5.7e-12 45.3 0.0 2.1 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 KKK26197.1 - 4.6e-13 48.7 0.0 8.5e-13 47.8 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain MFS_1 PF07690.16 KKK26198.1 - 6.8e-33 114.0 26.4 1.3e-30 106.6 23.4 2.7 1 1 0 2 2 2 2 Major Facilitator Superfamily SUIM_assoc PF16619.5 KKK26198.1 - 0.0025 17.8 1.0 0.0045 17.0 1.0 1.3 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 Imm57 PF15596.6 KKK26198.1 - 0.011 16.1 0.0 0.021 15.1 0.0 1.4 1 0 0 1 1 1 0 Immunity protein 57 UNC-93 PF05978.16 KKK26198.1 - 0.02 14.6 2.7 0.04 13.6 2.7 1.5 1 0 0 1 1 1 0 Ion channel regulatory protein UNC-93 Spt20 PF12090.8 KKK26198.1 - 1.4 8.5 5.0 2.1 7.9 5.0 1.2 1 0 0 1 1 1 0 Spt20 family DUF846 PF05832.12 KKK26199.1 - 3.2e-48 163.3 10.4 4.1e-48 163.0 10.4 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) TMEM220 PF15071.6 KKK26199.1 - 0.1 13.4 1.7 0.11 13.3 0.4 1.7 2 0 0 2 2 2 0 Transmembrane family 220, helix AstE_AspA PF04952.14 KKK26199.1 - 0.21 10.6 0.0 0.29 10.2 0.0 1.1 1 0 0 1 1 1 0 Succinylglutamate desuccinylase / Aspartoacylase family zf-CCHC PF00098.23 KKK26200.1 - 4.1e-44 146.8 86.0 7.4e-07 29.0 4.4 10.3 10 0 0 10 10 10 10 Zinc knuckle zf-CCHC_3 PF13917.6 KKK26200.1 - 2.8e-11 43.2 59.1 0.04 13.9 1.5 9.5 3 3 6 9 9 9 9 Zinc knuckle zf-CCHC_4 PF14392.6 KKK26200.1 - 1.2e-08 34.5 58.3 0.0067 16.1 0.7 10.1 10 0 0 10 10 10 8 Zinc knuckle zf-CCHC_2 PF13696.6 KKK26200.1 - 4e-05 23.3 78.7 0.00088 19.0 0.9 10.1 10 0 0 10 10 10 6 Zinc knuckle zf-CCHC_6 PF15288.6 KKK26200.1 - 0.056 13.3 0.1 0.056 13.3 0.1 9.1 8 2 1 9 9 9 0 Zinc knuckle HpcH_HpaI PF03328.14 KKK26201.1 - 7e-39 133.2 0.0 4.8e-38 130.5 0.0 1.9 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.6 KKK26201.1 - 3.5e-12 46.1 0.0 4.6e-06 26.0 0.0 2.1 2 0 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold Amino_oxidase PF01593.24 KKK26202.1 - 1.7e-74 251.8 0.1 6.3e-64 216.9 0.0 2.9 2 1 0 2 2 2 2 Flavin containing amine oxidoreductase SWIRM PF04433.17 KKK26202.1 - 4.5e-16 59.0 0.1 9.7e-16 57.9 0.1 1.5 1 0 0 1 1 1 1 SWIRM domain NAD_binding_8 PF13450.6 KKK26202.1 - 8.7e-07 29.1 0.1 1.9e-06 28.0 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HMG_box PF00505.19 KKK26202.1 - 0.00094 19.5 0.7 0.00094 19.5 0.7 3.0 1 1 1 2 2 2 1 HMG (high mobility group) box DAO PF01266.24 KKK26202.1 - 0.003 17.2 0.4 0.0068 16.0 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Orthopox_A5L PF06193.11 KKK26202.1 - 0.012 15.1 1.0 0.025 14.0 1.0 1.5 1 0 0 1 1 1 0 Orthopoxvirus A5L protein-like HMG_box_2 PF09011.10 KKK26202.1 - 0.013 16.1 0.7 0.013 16.1 0.7 2.0 1 1 1 2 2 2 0 HMG-box domain Pyr_redox_2 PF07992.14 KKK26202.1 - 0.027 13.7 0.3 0.37 10.0 0.1 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase SNARE_assoc PF09335.11 KKK26203.1 - 7.4e-12 45.8 3.3 7.4e-12 45.8 3.3 2.7 2 1 1 3 3 3 1 SNARE associated Golgi protein TMEMspv1-c74-12 PF11044.8 KKK26203.1 - 0.0047 16.9 0.2 0.013 15.5 0.2 1.7 1 0 0 1 1 1 1 Plectrovirus spv1-c74 ORF 12 transmembrane protein Patched PF02460.18 KKK26203.1 - 2 6.4 4.8 0.16 10.0 0.2 1.4 2 0 0 2 2 2 0 Patched family PhoD PF09423.10 KKK26204.1 - 0.0068 15.5 0.1 0.79 8.7 0.0 2.3 2 0 0 2 2 2 2 PhoD-like phosphatase Pyr_redox_2 PF07992.14 KKK26205.1 - 2.4e-48 164.9 0.1 2.8e-48 164.6 0.1 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KKK26205.1 - 1.9e-17 63.5 0.0 1.2e-15 57.6 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KKK26205.1 - 2.1e-15 57.0 0.1 1.9e-12 47.6 0.0 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KKK26205.1 - 0.00011 21.5 0.1 0.00041 19.7 0.0 1.8 2 0 0 2 2 2 1 Thi4 family NAD_binding_7 PF13241.6 KKK26205.1 - 0.00064 20.1 0.0 0.1 13.0 0.0 2.6 2 1 0 2 2 2 1 Putative NAD(P)-binding NAD_binding_8 PF13450.6 KKK26205.1 - 0.00084 19.5 0.8 0.064 13.5 0.1 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 KKK26205.1 - 0.0042 16.3 0.0 0.61 9.2 0.0 3.0 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) GIDA PF01134.22 KKK26205.1 - 0.011 14.9 3.1 1.8 7.5 0.0 3.5 4 1 1 5 5 5 0 Glucose inhibited division protein A FAD_binding_3 PF01494.19 KKK26205.1 - 0.025 13.8 0.7 3.2 6.9 0.0 2.4 2 1 0 2 2 2 0 FAD binding domain DAO PF01266.24 KKK26205.1 - 0.039 13.5 4.7 4.7 6.7 0.0 3.6 2 2 1 4 4 4 0 FAD dependent oxidoreductase FAD_oxidored PF12831.7 KKK26205.1 - 0.042 13.2 0.5 0.33 10.3 0.1 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase Shikimate_DH PF01488.20 KKK26205.1 - 0.093 12.8 0.0 11 6.0 0.0 3.0 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.24 KKK26205.1 - 0.32 10.0 3.9 0.36 9.8 0.4 2.6 3 1 2 5 5 5 0 FAD binding domain Pkinase PF00069.25 KKK26206.1 - 0.006 16.0 0.0 0.0078 15.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Sugar_tr PF00083.24 KKK26207.1 - 5.6e-106 355.1 26.5 6.7e-106 354.9 26.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKK26207.1 - 3.6e-16 59.0 31.5 7.9e-11 41.5 5.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily US6 PF17616.2 KKK26207.1 - 0.094 12.7 0.2 0.19 11.6 0.2 1.5 1 0 0 1 1 1 0 Viral unique short region 6 DUF1771 PF08590.10 KKK26208.1 - 5e-15 55.6 11.2 5e-15 55.6 11.2 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) Smr PF01713.21 KKK26208.1 - 6.4e-09 36.1 0.1 2.5e-08 34.2 0.1 2.1 1 0 0 1 1 1 1 Smr domain zf_CCCH_4 PF18345.1 KKK26208.1 - 9.2e-08 31.9 9.4 2.1e-05 24.4 1.2 2.9 2 1 0 2 2 2 2 Zinc finger domain zf-CCCH PF00642.24 KKK26208.1 - 2.8e-06 27.1 3.0 0.0045 16.9 0.1 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 KKK26208.1 - 7.7e-05 23.0 4.8 0.074 13.5 0.5 2.4 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 KKK26208.1 - 0.00017 21.8 2.3 0.25 11.6 0.0 2.4 1 1 1 2 2 2 2 Zinc-finger containing family zf-CCCH_4 PF18044.1 KKK26208.1 - 0.00021 21.0 12.2 0.004 16.9 1.4 3.1 2 1 0 2 2 2 2 CCCH-type zinc finger Torus PF16131.5 KKK26208.1 - 0.12 13.1 2.8 3.3 8.4 0.4 2.5 1 1 1 2 2 2 0 Torus domain MoCF_biosynth PF00994.24 KKK26209.1 - 3.3e-24 85.2 0.0 8.4e-23 80.6 0.0 2.3 1 1 0 1 1 1 1 Probable molybdopterin binding domain CinA_KH PF18146.1 KKK26209.1 - 0.022 14.9 0.0 0.064 13.4 0.0 1.7 2 0 0 2 2 2 0 Damage-inducible protein CinA KH domain Med26 PF08711.11 KKK26210.1 - 0.00017 21.6 0.2 0.00034 20.6 0.2 1.6 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Fungal_trans_2 PF11951.8 KKK26211.1 - 0.061 12.1 0.0 0.1 11.4 0.0 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain Mito_carr PF00153.27 KKK26212.1 - 5e-46 154.6 2.6 4.2e-15 55.4 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Sugar_tr PF00083.24 KKK26214.1 - 1.4e-30 106.6 4.8 1.7e-30 106.3 4.8 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKK26214.1 - 3.3e-10 39.4 21.0 1.2e-09 37.6 18.9 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KKK26214.1 - 0.071 12.0 9.0 0.09 11.6 9.0 1.3 1 1 0 1 1 1 0 MFS_1 like family AMP-binding PF00501.28 KKK26215.1 - 6.3e-66 222.7 0.0 9.9e-66 222.1 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 KKK26215.1 - 1.7e-23 83.1 0.0 1.8e-22 79.7 0.0 2.4 3 0 0 3 3 3 1 Condensation domain PP-binding PF00550.25 KKK26215.1 - 1.7e-10 41.1 0.0 5.2e-10 39.5 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KKK26215.1 - 0.0027 18.7 0.0 0.011 16.7 0.0 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ATP-grasp_2 PF08442.10 KKK26216.1 - 1.5e-54 184.6 0.0 2.1e-54 184.2 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.19 KKK26216.1 - 1.9e-10 40.8 0.2 3e-10 40.1 0.2 1.3 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 KKK26216.1 - 3.1e-10 39.9 0.0 1.4e-09 37.7 0.0 1.9 1 1 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 KKK26216.1 - 0.0085 15.9 0.0 0.023 14.5 0.0 1.8 1 1 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp PF02222.22 KKK26216.1 - 0.019 14.6 0.0 0.057 13.0 0.0 1.7 1 1 0 1 1 1 0 ATP-grasp domain CPSase_L_D2 PF02786.17 KKK26216.1 - 0.045 13.2 0.0 0.1 12.1 0.0 1.6 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain TauD PF02668.16 KKK26217.1 - 2.1e-10 40.9 0.3 0.00013 21.9 0.1 2.2 2 0 0 2 2 2 2 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 KKK26217.1 - 0.091 11.9 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 CsiD VEGFR-2_TMD PF17988.1 KKK26218.1 - 0.21 11.1 1.2 0.38 10.2 1.2 1.3 1 0 0 1 1 1 0 VEGFR-2 Transmembrane domain Piwi PF02171.17 KKK26219.1 - 4.6e-73 246.1 0.0 8.9e-73 245.1 0.0 1.5 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 KKK26219.1 - 9.7e-19 68.4 0.0 1.8e-18 67.5 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL1 PF08699.10 KKK26219.1 - 3.5e-14 52.2 0.2 8.2e-14 51.0 0.2 1.7 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoL2 PF16488.5 KKK26219.1 - 3.6e-11 43.2 0.0 1.2e-10 41.6 0.0 2.0 1 0 0 1 1 1 1 Argonaute linker 2 domain PAZ PF02170.22 KKK26219.1 - 2.1e-09 37.3 0.0 6.5e-09 35.7 0.0 1.8 1 1 0 1 1 1 1 PAZ domain ArgoMid PF16487.5 KKK26219.1 - 0.0012 19.1 0.0 0.0036 17.5 0.0 1.8 1 0 0 1 1 1 1 Mid domain of argonaute DUF4381 PF14316.6 KKK26220.1 - 0.068 13.4 0.4 0.13 12.5 0.2 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) NAM-associated PF14303.6 KKK26220.1 - 1.3 9.8 6.6 11 6.7 0.0 2.2 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain Ctr PF04145.15 KKK26220.1 - 1.9 9.1 0.0 1.9 9.1 0.0 2.3 2 1 1 3 3 3 0 Ctr copper transporter family APH PF01636.23 KKK26222.1 - 0.095 12.6 0.3 4.1 7.2 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family MFS_1 PF07690.16 KKK26223.1 - 3.6e-28 98.5 21.1 2.3e-27 95.9 19.0 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF3040 PF11239.8 KKK26223.1 - 4.3 7.7 10.9 2.7 8.3 0.1 3.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3040) Glyco_transf_90 PF05686.12 KKK26224.1 - 2.8e-17 62.7 3.0 1.9e-13 50.1 2.4 2.9 2 1 0 2 2 2 2 Glycosyl transferase family 90 Ferric_reduct PF01794.19 KKK26224.1 - 1.2e-10 41.5 0.8 1.2e-10 41.5 0.8 2.2 2 0 0 2 2 2 1 Ferric reductase like transmembrane component tRNA_synthFbeta PF17759.1 KKK26225.1 - 8.8e-50 169.1 0.0 1.2e-49 168.6 0.0 1.2 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain PhetRS_B1 PF18262.1 KKK26225.1 - 2.5e-34 117.3 0.2 7.1e-33 112.7 0.1 2.4 2 0 0 2 2 2 1 Phe-tRNA synthetase beta subunit B1 domain B3_4 PF03483.17 KKK26225.1 - 1.4e-24 86.8 0.1 2.8e-24 85.7 0.1 1.6 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.15 KKK26225.1 - 1.4e-17 63.8 0.0 4.2e-15 55.8 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetase B5 domain HEAT PF02985.22 KKK26226.1 - 7.8e-39 128.4 11.5 0.015 15.5 0.1 13.1 13 0 0 13 13 13 10 HEAT repeat HEAT_2 PF13646.6 KKK26226.1 - 1.3e-37 128.1 1.6 9.6e-11 41.9 0.0 8.2 2 2 7 9 9 9 8 HEAT repeats HEAT_EZ PF13513.6 KKK26226.1 - 5.1e-14 52.4 6.2 0.015 15.8 0.0 9.4 7 3 4 11 11 11 4 HEAT-like repeat Vac14_Fab1_bd PF12755.7 KKK26226.1 - 5.6e-12 46.1 1.0 0.0032 18.0 0.0 7.3 5 2 3 8 8 8 1 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 KKK26226.1 - 4.8e-09 36.4 8.5 0.017 15.1 0.2 5.6 4 1 0 6 6 6 2 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 KKK26226.1 - 1.1e-06 27.5 5.4 1.8e-05 23.5 0.7 3.8 3 1 1 4 4 4 2 Adaptin N terminal region RTP1_C1 PF10363.9 KKK26226.1 - 1.7e-05 25.0 4.6 0.65 10.2 0.1 4.7 4 1 1 5 5 5 2 Required for nuclear transport of RNA pol II C-terminus 1 CLASP_N PF12348.8 KKK26226.1 - 0.0018 17.9 0.7 0.14 11.7 0.1 3.6 3 2 1 4 4 4 1 CLASP N terminal Proteasom_PSMB PF10508.9 KKK26226.1 - 0.0077 14.8 2.2 0.47 8.9 0.1 2.4 2 1 0 2 2 2 2 Proteasome non-ATPase 26S subunit TetR_C_16 PF17920.1 KKK26226.1 - 0.0077 16.5 0.8 14 6.0 0.0 4.0 3 1 1 4 4 4 1 Tetracyclin repressor-like, C-terminal domain NT-C2 PF10358.9 KKK26227.1 - 3.4e-36 124.1 0.0 6.3e-36 123.3 0.0 1.5 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins SLS PF14611.6 KKK26227.1 - 7.8e-36 124.0 0.1 2.5e-35 122.3 0.0 1.9 2 0 0 2 2 2 1 Mitochondrial inner-membrane-bound regulator TetR_C_15 PF17918.1 KKK26227.1 - 0.0021 18.8 0.1 0.024 15.4 0.0 2.4 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain APG6_N PF17675.1 KKK26228.1 - 0.0047 17.5 2.7 0.0056 17.2 2.7 1.1 1 0 0 1 1 1 1 Apg6 coiled-coil region UPF0242 PF06785.11 KKK26228.1 - 0.014 15.5 1.9 0.016 15.3 1.9 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Jnk-SapK_ap_N PF09744.9 KKK26228.1 - 0.033 14.4 6.5 0.042 14.1 6.5 1.1 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Exonuc_VII_L PF02601.15 KKK26228.1 - 0.038 13.6 0.6 0.04 13.5 0.6 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit YaiA PF16362.5 KKK26228.1 - 0.06 13.5 0.7 0.06 13.5 0.7 1.9 2 0 0 2 2 2 0 YaiA protein She9_MDM33 PF05546.11 KKK26228.1 - 0.1 12.4 4.0 0.14 12.0 4.0 1.1 1 0 0 1 1 1 0 She9 / Mdm33 family DinB PF05163.12 KKK26228.1 - 0.11 12.5 0.9 0.14 12.1 0.9 1.1 1 0 0 1 1 1 0 DinB family YojJ PF10372.9 KKK26228.1 - 0.4 10.8 2.6 0.82 9.8 1.5 1.9 1 1 1 2 2 2 0 Bacterial membrane-spanning protein N-terminus TMPIT PF07851.13 KKK26228.1 - 1.1 8.5 3.5 1.4 8.1 3.5 1.0 1 0 0 1 1 1 0 TMPIT-like protein Stathmin PF00836.19 KKK26228.1 - 1.8 8.5 13.4 0.15 12.0 8.6 1.6 2 0 0 2 2 2 0 Stathmin family PAH PF02671.21 KKK26229.1 - 6.2e-10 39.1 0.8 5.5 7.2 0.3 10.4 7 2 2 9 9 9 2 Paired amphipathic helix repeat DUF2357 PF09823.9 KKK26229.1 - 0.00099 18.4 0.0 12 5.0 0.0 5.1 4 2 4 8 8 8 1 Domain of unknown function (DUF2357) NUC130_3NT PF08158.12 KKK26229.1 - 0.0029 17.9 16.6 23 5.4 0.1 9.7 11 1 1 12 12 12 0 NUC130/3NT domain EcoEI_R_C PF08463.10 KKK26229.1 - 0.01 16.0 0.1 12 6.0 0.3 4.8 3 1 4 7 7 7 1 EcoEI R protein C-terminal PIN_9 PF18477.1 KKK26229.1 - 0.036 14.4 6.4 63 3.9 0.0 7.0 6 3 3 10 10 10 0 PIN like domain RP853 PF17542.2 KKK26229.1 - 0.094 11.8 0.8 3 6.9 0.2 3.0 2 1 1 3 3 3 0 Uncharacterized RP853 SOG2 PF10428.9 KKK26229.1 - 0.17 11.1 9.1 0.31 10.2 9.1 1.4 1 0 0 1 1 1 0 RAM signalling pathway protein DUF1732 PF08340.11 KKK26229.1 - 0.19 11.7 0.1 3.7 7.6 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF1732) Myotub-related PF06602.14 KKK26230.1 - 3.3e-151 503.2 0.0 6.2e-151 502.3 0.0 1.4 1 1 0 1 1 1 1 Myotubularin-like phosphatase domain Ribosomal_S3_C PF00189.20 KKK26230.1 - 1.3e-23 83.3 0.1 4.2e-23 81.7 0.2 1.9 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 KKK26230.1 - 4.6e-11 42.4 0.1 9e-11 41.4 0.1 1.5 1 0 0 1 1 1 1 KH domain Myb_DNA-binding PF00249.31 KKK26231.1 - 1.9e-14 53.6 2.5 2.6e-11 43.5 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KKK26231.1 - 3e-06 27.4 3.7 0.0026 18.0 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain AGOG PF09171.10 KKK26231.1 - 0.14 11.5 0.1 0.19 11.0 0.1 1.1 1 0 0 1 1 1 0 N-glycosylase/DNA lyase FAD_binding_2 PF00890.24 KKK26232.1 - 1.2e-124 416.6 3.4 1.8e-124 416.1 3.4 1.3 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 KKK26232.1 - 1.4e-44 151.1 1.6 2.1e-44 150.6 1.6 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.14 KKK26232.1 - 7.3e-06 25.4 0.2 0.0011 18.3 0.1 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KKK26232.1 - 2.6e-05 23.5 1.3 0.044 12.9 2.7 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A Thi4 PF01946.17 KKK26232.1 - 7.2e-05 22.1 0.2 0.045 13.0 0.1 2.3 2 0 0 2 2 2 2 Thi4 family FAD_binding_3 PF01494.19 KKK26232.1 - 0.0028 17.0 0.8 0.0075 15.6 0.2 2.0 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 KKK26232.1 - 0.0055 16.3 0.8 0.016 14.9 0.8 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KKK26232.1 - 0.19 10.4 1.0 0.73 8.5 0.5 2.2 3 0 0 3 3 3 0 HI0933-like protein PARP PF00644.20 KKK26234.1 - 2.3e-61 206.8 1.2 2.7e-61 206.6 0.0 1.7 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.14 KKK26234.1 - 5.3e-42 143.1 0.0 8.9e-42 142.4 0.0 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.15 KKK26234.1 - 4e-24 84.5 0.9 8.7e-24 83.4 0.9 1.6 1 0 0 1 1 1 1 WGR domain BRCT PF00533.26 KKK26234.1 - 9.2e-10 38.8 0.1 2.4e-09 37.4 0.1 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 KKK26234.1 - 4.4e-08 32.9 0.2 1e-07 31.8 0.2 1.6 1 0 0 1 1 1 1 twin BRCT domain BRCT_2 PF16589.5 KKK26234.1 - 0.0004 20.7 0.3 0.00091 19.6 0.3 1.6 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain Ribosomal_60s PF00428.19 KKK26234.1 - 0.066 13.8 4.0 0.17 12.5 4.0 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein FAM176 PF14851.6 KKK26234.1 - 0.77 9.4 3.3 5.8 6.6 2.6 2.2 2 0 0 2 2 2 0 FAM176 family p450 PF00067.22 KKK26235.1 - 4.8e-13 48.7 0.0 6e-13 48.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 zf-C2H2 PF00096.26 KKK26236.1 - 0.00025 21.3 3.8 0.00025 21.3 3.8 3.4 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 KKK26236.1 - 0.0063 16.2 2.7 0.0063 16.2 2.7 2.7 2 0 0 2 2 2 1 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.6 KKK26236.1 - 0.014 16.2 3.1 0.014 16.2 3.1 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger C1_4 PF07975.12 KKK26236.1 - 0.17 12.1 0.2 0.17 12.1 0.2 2.2 3 0 0 3 3 3 0 TFIIH C1-like domain MSA-2c PF12238.8 KKK26236.1 - 0.18 11.8 2.5 0.36 10.8 2.5 1.5 1 0 0 1 1 1 0 Merozoite surface antigen 2c zf-H2C2_2 PF13465.6 KKK26236.1 - 0.92 10.1 19.2 0.63 10.6 4.7 3.7 3 0 0 3 3 3 0 Zinc-finger double domain Cpn60_TCP1 PF00118.24 KKK26237.1 - 1.7e-149 498.6 13.4 1.9e-149 498.4 13.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family AAA PF00004.29 KKK26238.1 - 3e-40 137.7 0.0 5.3e-40 136.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KKK26238.1 - 8.7e-06 25.4 0.1 2e-05 24.3 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 KKK26238.1 - 0.00012 22.1 0.1 0.00062 19.8 0.0 2.2 3 1 0 3 3 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KKK26238.1 - 0.00015 22.1 0.0 0.0055 17.0 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 KKK26238.1 - 0.00049 20.5 0.1 0.011 16.1 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_2 PF07724.14 KKK26238.1 - 0.00052 20.2 0.0 0.0016 18.6 0.0 1.7 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 KKK26238.1 - 0.0014 17.8 0.0 0.0026 17.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 KKK26238.1 - 0.0093 15.7 0.0 0.018 14.8 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 KKK26238.1 - 0.019 15.2 0.1 0.063 13.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KKK26238.1 - 0.03 13.8 0.0 0.095 12.2 0.0 1.8 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 KKK26238.1 - 0.046 13.9 0.0 0.095 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KKK26238.1 - 0.063 13.7 0.0 0.15 12.4 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_3 PF07726.11 KKK26238.1 - 0.088 12.7 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 KKK26238.1 - 0.094 12.4 0.0 0.28 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KKK26238.1 - 0.11 12.3 0.1 0.59 9.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 KKK26238.1 - 0.11 12.5 0.0 0.25 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KKK26238.1 - 0.14 12.7 0.0 0.5 10.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain BCS1_N PF08740.11 KKK26239.1 - 1.9e-48 164.9 0.6 2.6e-48 164.5 0.6 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 KKK26239.1 - 2e-18 67.1 0.0 3.5e-18 66.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KKK26239.1 - 8.6e-05 23.0 0.0 0.00026 21.4 0.0 1.8 2 0 0 2 2 1 1 AAA ATPase domain DUF815 PF05673.13 KKK26239.1 - 0.00045 19.5 0.0 0.00072 18.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_21 PF13304.6 KKK26239.1 - 0.0024 17.7 0.0 0.0044 16.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_7 PF12775.7 KKK26239.1 - 0.0029 17.1 0.0 0.0066 16.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_5 PF07728.14 KKK26239.1 - 0.0093 16.0 0.0 0.028 14.4 0.0 1.9 1 1 1 2 2 2 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 KKK26239.1 - 0.012 16.1 0.0 0.023 15.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KKK26239.1 - 0.013 15.3 0.0 0.063 13.0 0.0 2.0 1 1 1 2 2 2 0 AAA domain RNA_helicase PF00910.22 KKK26239.1 - 0.015 15.7 0.0 0.041 14.3 0.0 1.8 2 0 0 2 2 1 0 RNA helicase AAA_25 PF13481.6 KKK26239.1 - 0.019 14.6 0.0 0.091 12.3 0.0 2.0 1 1 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KKK26239.1 - 0.019 15.5 0.0 0.044 14.3 0.0 1.6 1 0 0 1 1 1 0 ABC transporter PPV_E1_C PF00519.17 KKK26239.1 - 0.02 13.8 0.0 0.029 13.2 0.0 1.2 1 0 0 1 1 1 0 Papillomavirus helicase AAA_22 PF13401.6 KKK26239.1 - 0.035 14.4 0.0 0.11 12.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KKK26239.1 - 0.037 14.2 0.0 0.11 12.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 KKK26239.1 - 0.041 13.6 0.0 0.1 12.3 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATPase PF06745.13 KKK26239.1 - 0.052 12.9 0.0 0.11 11.8 0.0 1.5 1 0 0 1 1 1 0 KaiC RsgA_GTPase PF03193.16 KKK26239.1 - 0.066 13.1 0.0 0.39 10.6 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase MMR_HSR1 PF01926.23 KKK26239.1 - 0.093 12.8 0.0 0.22 11.6 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase RuvB_N PF05496.12 KKK26239.1 - 0.11 12.2 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Rad17 PF03215.15 KKK26239.1 - 0.13 12.2 0.0 0.31 10.9 0.0 1.6 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_11 PF13086.6 KKK26239.1 - 0.18 11.6 0.0 0.31 10.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain Lactamase_B_2 PF12706.7 KKK26240.1 - 1e-32 113.3 0.0 8.2e-32 110.4 0.0 2.0 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KKK26240.1 - 2.9e-12 46.8 0.0 2.2e-11 43.9 0.0 2.3 2 1 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KKK26240.1 - 5.2e-06 26.6 0.3 0.0025 17.8 0.1 2.6 2 1 0 2 2 2 2 Metallo-beta-lactamase superfamily DUF2841 PF11001.8 KKK26241.1 - 2.8e-49 166.3 0.1 4.3e-49 165.7 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) TGT PF01702.18 KKK26242.1 - 3.3e-70 237.0 0.0 4.1e-70 236.7 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase JmjN PF02375.17 KKK26243.1 - 4.8e-18 64.8 2.0 7.5e-18 64.2 2.0 1.3 1 0 0 1 1 1 1 jmjN domain GIY-YIG PF01541.24 KKK26244.1 - 2.1e-12 47.1 0.0 3.6e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 GIY-YIG catalytic domain FANCL_C PF11793.8 KKK26244.1 - 0.00022 21.4 5.4 0.00037 20.6 5.4 1.3 1 0 0 1 1 1 1 FANCL C-terminal domain Prok-RING_1 PF14446.6 KKK26244.1 - 0.27 11.2 8.8 0.057 13.4 4.3 2.0 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 TP1 PF02079.16 KKK26244.1 - 5.3 7.0 10.1 2.2 8.2 1.5 2.4 2 0 0 2 2 2 0 Nuclear transition protein 1 Thymidylate_kin PF02223.17 KKK26245.1 - 1.9e-46 158.1 0.0 2.2e-46 157.9 0.0 1.0 1 0 0 1 1 1 1 Thymidylate kinase KTI12 PF08433.10 KKK26245.1 - 0.0032 17.0 0.0 0.0076 15.7 0.0 1.5 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_28 PF13521.6 KKK26245.1 - 0.0086 16.3 0.0 0.011 15.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain CPT PF07931.12 KKK26245.1 - 0.014 15.3 0.0 0.026 14.4 0.0 1.4 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_18 PF13238.6 KKK26245.1 - 0.15 12.6 0.0 0.5 10.9 0.0 1.9 1 1 1 2 2 2 0 AAA domain Sugar_tr PF00083.24 KKK26246.1 - 1.2e-28 100.1 9.7 1.4e-28 100.0 9.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKK26246.1 - 1.7e-08 33.8 8.7 2.1e-08 33.5 8.7 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily ABC2_membrane PF01061.24 KKK26246.1 - 0.0009 18.7 7.9 0.0009 18.7 7.9 1.5 2 0 0 2 2 2 1 ABC-2 type transporter Peptidase_U4 PF03419.13 KKK26246.1 - 0.1 11.8 4.0 0.14 11.4 4.0 1.2 1 0 0 1 1 1 0 Sporulation factor SpoIIGA Peptidase_A8 PF01252.18 KKK26246.1 - 0.11 12.8 3.0 0.12 12.6 2.4 1.4 1 1 0 1 1 1 0 Signal peptidase (SPase) II DUF3792 PF12670.7 KKK26246.1 - 2.4 8.4 9.4 4.1 7.6 4.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3792) Exo5 PF09810.9 KKK26247.1 - 4.6e-141 470.6 0.0 5.8e-141 470.3 0.0 1.1 1 0 0 1 1 1 1 Exonuclease V - a 5' deoxyribonuclease PDDEXK_1 PF12705.7 KKK26247.1 - 0.00043 20.3 0.0 0.78 9.6 0.0 3.1 2 1 0 2 2 2 2 PD-(D/E)XK nuclease superfamily DUF3799 PF12684.7 KKK26247.1 - 0.084 12.6 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 PDDEXK-like domain of unknown function (DUF3799) DUF3445 PF11927.8 KKK26248.1 - 2.5e-55 187.5 0.0 3.1e-55 187.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Glyco_transf_22 PF03901.17 KKK26249.1 - 2.3e-83 280.8 16.1 2.6e-83 280.6 16.1 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Aldo_ket_red PF00248.21 KKK26250.1 - 2.8e-51 174.5 0.0 3.3e-50 171.0 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family PIG-U PF06728.13 KKK26251.1 - 4.6e-121 404.5 30.3 5.8e-121 404.1 30.3 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U 8TM_micro PF17028.5 KKK26251.1 - 0.61 9.7 12.7 1.1 8.9 12.7 1.4 1 0 0 1 1 1 0 8TM Microsporidial transmembrane domain Pescadillo_N PF06732.11 KKK26252.1 - 9.6e-125 415.6 0.0 9.6e-125 415.6 0.0 1.7 2 0 0 2 2 2 1 Pescadillo N-terminus BRCT_2 PF16589.5 KKK26252.1 - 0.00031 21.1 0.0 0.003 17.9 0.0 2.4 1 1 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 KKK26252.1 - 0.02 15.2 0.0 0.58 10.6 0.0 3.1 2 1 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain DUF2457 PF10446.9 KKK26252.1 - 7.3 5.6 36.3 16 4.5 36.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Aldedh PF00171.22 KKK26253.1 - 3e-166 553.5 0.7 3.4e-166 553.3 0.7 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 KKK26253.1 - 0.15 11.5 0.0 0.7 9.3 0.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1487) Ribosomal_L36 PF00444.18 KKK26254.1 - 0.00049 20.2 1.0 0.00082 19.5 1.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L36 PALP PF00291.25 KKK26255.1 - 5.3e-76 255.8 1.8 6.8e-76 255.5 1.8 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.18 KKK26255.1 - 9.7e-46 153.5 0.0 1.3e-22 79.4 0.0 2.4 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase Complex1_LYR PF05347.15 KKK26256.1 - 9e-13 48.1 0.4 1.6e-12 47.3 0.4 1.5 1 1 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KKK26256.1 - 3e-08 34.3 0.4 4.3e-08 33.8 0.4 1.3 1 0 0 1 1 1 1 Complex1_LYR-like GTP_EFTU PF00009.27 KKK26257.1 - 1e-58 198.1 0.3 1.8e-58 197.3 0.3 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 KKK26257.1 - 9.1e-34 115.8 0.0 2e-33 114.7 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.6 KKK26257.1 - 1e-32 112.1 0.0 2.3e-32 110.9 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 KKK26257.1 - 5.5e-23 80.8 0.0 1.2e-22 79.7 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KKK26257.1 - 2.3e-11 43.9 0.1 5.7e-11 42.7 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 KKK26257.1 - 7.1e-06 25.9 0.0 1.7e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain MMR_HSR1 PF01926.23 KKK26257.1 - 0.17 12.0 0.0 0.37 10.9 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase Acetyltransf_1 PF00583.25 KKK26258.1 - 2.4e-10 40.6 0.0 3.7e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KKK26258.1 - 8.2e-06 26.2 0.1 1.3e-05 25.5 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KKK26258.1 - 1e-05 25.5 0.0 1.7e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KKK26258.1 - 0.0059 16.5 0.0 0.011 15.7 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein HIG_1_N PF04588.13 KKK26259.1 - 2.9e-27 94.6 0.3 4e-27 94.2 0.3 1.2 1 0 0 1 1 1 1 Hypoxia induced protein conserved region DUF2514 PF10721.9 KKK26259.1 - 0.03 14.4 4.3 0.043 13.8 4.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) Abhydrolase_1 PF00561.20 KKK26260.1 - 6e-48 163.7 0.0 1.2e-46 159.5 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 KKK26260.1 - 9.5e-05 22.2 0.0 0.00023 20.9 0.0 1.6 1 0 0 1 1 1 1 Putative esterase CMD PF02627.20 KKK26261.1 - 5.9e-08 32.7 0.3 2.3e-05 24.4 0.2 2.5 1 1 1 2 2 2 2 Carboxymuconolactone decarboxylase family CPSase_L_D3 PF02787.19 KKK26261.1 - 0.0096 16.3 0.1 0.013 15.8 0.1 1.2 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain GBP_C PF02841.14 KKK26261.1 - 0.066 12.6 0.2 0.1 12.0 0.2 1.2 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain Mtc PF03820.17 KKK26262.1 - 1.2e-118 395.8 0.1 1.5e-118 395.4 0.1 1.1 1 0 0 1 1 1 1 Tricarboxylate carrier WD40 PF00400.32 KKK26262.1 - 1.9e-16 60.1 17.8 0.00017 22.3 0.1 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKK26262.1 - 3.8e-07 30.3 0.3 0.033 14.5 0.0 4.6 5 1 1 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Cu-oxidase_3 PF07732.15 KKK26263.1 - 2.4e-12 46.9 0.0 9.4e-08 32.1 0.0 2.3 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 KKK26263.1 - 2.7e-10 40.1 0.0 0.00061 19.5 0.0 3.1 2 1 0 2 2 2 2 Multicopper oxidase Cupredoxin_1 PF13473.6 KKK26263.1 - 0.019 15.1 0.0 3.5 7.8 0.0 2.5 2 0 0 2 2 2 0 Cupredoxin-like domain SLC35F PF06027.12 KKK26264.1 - 5.7e-99 331.4 20.5 6.7e-99 331.2 20.5 1.0 1 0 0 1 1 1 1 Solute carrier family 35 CRT-like PF08627.10 KKK26264.1 - 5e-10 38.8 1.6 8.4e-10 38.1 1.6 1.3 1 0 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like EamA PF00892.20 KKK26264.1 - 2.5e-06 27.7 31.7 0.0022 18.2 10.0 2.1 2 0 0 2 2 2 2 EamA-like transporter family NFACT-R_1 PF05670.13 KKK26265.1 - 4.3e-26 91.7 0.2 1.2e-22 80.7 0.0 2.4 2 0 0 2 2 2 2 NFACT protein RNA binding domain Presenilin PF01080.17 KKK26265.1 - 8.8 5.0 5.2 11 4.7 5.2 1.2 1 0 0 1 1 1 0 Presenilin MFS_1 PF07690.16 KKK26266.1 - 7.3e-18 64.6 34.6 1.7e-15 56.9 29.9 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.13 KKK26266.1 - 5.1e-17 62.2 1.8 5.1e-17 62.2 1.8 1.7 2 0 0 2 2 2 1 Nodulin-like Serinc PF03348.15 KKK26268.1 - 1.3e-161 538.4 10.9 1.5e-161 538.2 10.9 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) DUF21 PF01595.20 KKK26268.1 - 0.0072 16.1 0.3 0.0072 16.1 0.3 3.8 3 1 1 4 4 4 1 Cyclin M transmembrane N-terminal domain Chitin_synth_2 PF03142.15 KKK26269.1 - 1.8e-228 759.5 0.0 3.3e-228 758.6 0.0 1.3 2 0 0 2 2 2 1 Chitin synthase DEK_C PF08766.11 KKK26269.1 - 1.1e-16 60.5 0.4 5.7e-16 58.2 0.7 2.0 2 0 0 2 2 2 1 DEK C terminal domain Glyco_trans_2_3 PF13632.6 KKK26269.1 - 1.6e-13 51.0 1.6 1.6e-13 51.0 1.6 1.8 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Cyt-b5 PF00173.28 KKK26269.1 - 3.1e-13 49.7 0.1 5.7e-07 29.6 0.0 3.1 2 1 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_tranf_2_3 PF13641.6 KKK26269.1 - 1e-11 45.2 0.0 1.2e-10 41.7 0.0 2.3 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Myosin_head PF00063.21 KKK26269.1 - 2.7e-10 39.2 0.0 3.6e-09 35.4 0.0 2.0 1 1 1 2 2 2 1 Myosin head (motor domain) Glyco_transf_21 PF13506.6 KKK26269.1 - 0.0013 18.2 0.0 0.0043 16.5 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 KKK26269.1 - 0.0064 16.3 0.0 0.36 10.6 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferase family 2 MutL_C PF08676.11 KKK26270.1 - 7.9e-23 80.9 0.0 1.8e-22 79.7 0.0 1.6 1 0 0 1 1 1 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.19 KKK26270.1 - 1.3e-18 66.8 0.0 9.3e-18 64.0 0.0 2.4 3 0 0 3 3 3 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 KKK26270.1 - 1.7e-09 37.6 0.0 4.2e-09 36.4 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Zn_clus PF00172.18 KKK26270.1 - 1.6e-06 28.1 7.5 3.1e-06 27.2 7.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HATPase_c PF02518.26 KKK26270.1 - 9.4e-06 26.1 0.2 3.1e-05 24.4 0.0 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GCN5L1 PF06320.13 KKK26271.1 - 2.2e-18 66.4 1.0 3.1e-18 66.0 1.0 1.1 1 0 0 1 1 1 1 GCN5-like protein 1 (GCN5L1) Cylicin_N PF15241.6 KKK26271.1 - 0.14 12.3 4.9 0.22 11.7 4.9 1.2 1 0 0 1 1 1 0 Cylicin N-terminus HSP90 PF00183.18 KKK26271.1 - 0.16 10.8 0.2 0.24 10.3 0.2 1.2 1 0 0 1 1 1 0 Hsp90 protein BTV_NS2 PF04514.12 KKK26271.1 - 0.26 10.1 4.0 0.33 9.7 4.0 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 HWE_HK PF07536.14 KKK26271.1 - 1.2 9.9 5.3 3.3 8.5 1.2 2.3 1 1 0 2 2 2 0 HWE histidine kinase FlgT_N PF16548.5 KKK26271.1 - 2.8 8.6 6.5 0.88 10.2 2.3 2.1 1 1 1 2 2 2 0 Flagellar assembly protein T, N-terminal domain Med11 PF10280.9 KKK26271.1 - 7.6 7.0 10.1 15 6.1 10.1 1.7 1 1 0 1 1 1 0 Mediator complex protein Ndc1_Nup PF09531.10 KKK26271.1 - 9.7 4.7 7.3 10 4.7 7.3 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup ArsA_ATPase PF02374.15 KKK26272.1 - 1.9e-114 381.9 0.0 2.2e-114 381.7 0.0 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_31 PF13614.6 KKK26272.1 - 2e-13 50.6 0.2 2.7e-12 47.0 0.0 2.4 2 1 0 2 2 2 1 AAA domain CbiA PF01656.23 KKK26272.1 - 6.8e-13 48.8 0.0 1.6e-12 47.6 0.0 1.8 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ParA PF10609.9 KKK26272.1 - 5.3e-06 26.1 1.0 0.00019 20.9 0.1 2.4 2 0 0 2 2 2 1 NUBPL iron-transfer P-loop NTPase Fer4_NifH PF00142.18 KKK26272.1 - 5.7e-06 26.0 0.1 1.3e-05 24.8 0.0 1.6 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.22 KKK26272.1 - 4.2e-05 23.3 0.2 0.0016 18.1 0.0 2.5 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain CBP_BcsQ PF06564.12 KKK26272.1 - 0.00011 21.7 0.1 0.00042 19.9 0.0 1.9 2 0 0 2 2 2 1 Cellulose biosynthesis protein BcsQ PhoH PF02562.16 KKK26272.1 - 0.027 13.9 0.0 0.078 12.4 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein A1_Propeptide PF07966.12 KKK26272.1 - 0.03 14.2 0.1 0.12 12.2 0.1 2.2 1 0 0 1 1 1 0 A1 Propeptide AAA_25 PF13481.6 KKK26272.1 - 0.044 13.4 0.0 0.18 11.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 KKK26272.1 - 0.089 13.2 0.0 0.14 12.5 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain NB-ARC PF00931.22 KKK26272.1 - 0.11 11.6 0.0 0.22 10.7 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain RecG_N PF17190.4 KKK26272.1 - 0.3 11.9 2.5 0.48 11.2 0.3 2.3 3 0 0 3 3 3 0 RecG N-terminal helical domain eIF3_N PF09440.10 KKK26274.1 - 7.4e-51 172.1 0.9 1.9e-50 170.7 0.9 1.8 1 0 0 1 1 1 1 eIF3 subunit 6 N terminal domain PCI PF01399.27 KKK26274.1 - 2.2e-14 53.8 0.1 7.2e-14 52.2 0.0 1.9 2 0 0 2 2 2 1 PCI domain RPN7 PF10602.9 KKK26274.1 - 0.047 13.4 0.0 0.089 12.5 0.0 1.5 1 0 0 1 1 1 0 26S proteasome subunit RPN7 Img2 PF05046.14 KKK26275.1 - 5.7e-27 93.8 0.0 1.1e-26 93.0 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) ARID PF01388.21 KKK26276.1 - 5.1e-20 71.9 0.0 1.4e-19 70.5 0.0 1.8 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain BAF250_C PF12031.8 KKK26276.1 - 0.0096 15.2 0.0 0.022 14.1 0.0 1.5 1 0 0 1 1 1 1 SWI/SNF-like complex subunit BAF250/Osa AAA PF00004.29 KKK26277.1 - 2e-46 157.7 0.5 6.6e-46 156.0 0.0 2.1 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 KKK26277.1 - 1.2e-10 41.2 0.1 7.6e-10 38.6 0.0 2.2 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_2 PF07724.14 KKK26277.1 - 9.5e-09 35.6 0.0 2e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 KKK26277.1 - 1e-08 35.2 0.5 3.5e-08 33.6 0.1 2.1 2 2 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KKK26277.1 - 1e-07 32.5 0.4 2.6e-05 24.6 0.0 2.8 2 1 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 KKK26277.1 - 2.7e-05 24.4 1.2 0.0051 17.1 0.1 2.7 1 1 1 2 2 2 1 AAA domain DUF815 PF05673.13 KKK26277.1 - 6.8e-05 22.1 0.0 0.00014 21.2 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_14 PF13173.6 KKK26277.1 - 0.00015 21.8 0.0 0.00057 19.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_lid_3 PF17862.1 KKK26277.1 - 0.0002 21.1 0.0 0.00045 20.0 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain TsaE PF02367.17 KKK26277.1 - 0.00027 20.9 0.0 0.02 14.9 0.0 2.3 1 1 1 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE RuvB_N PF05496.12 KKK26277.1 - 0.0003 20.6 0.0 0.00087 19.1 0.0 1.8 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_7 PF12775.7 KKK26277.1 - 0.00049 19.6 0.0 0.0068 15.9 0.1 2.5 2 1 0 2 2 2 1 P-loop containing dynein motor region AAA_18 PF13238.6 KKK26277.1 - 0.0012 19.3 0.0 0.0037 17.8 0.0 1.8 2 0 0 2 2 1 1 AAA domain NTPase_1 PF03266.15 KKK26277.1 - 0.0013 18.7 0.0 0.0049 16.8 0.0 1.9 2 0 0 2 2 2 1 NTPase RNA_helicase PF00910.22 KKK26277.1 - 0.0014 19.0 0.0 0.0031 17.9 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_33 PF13671.6 KKK26277.1 - 0.002 18.3 0.0 0.0043 17.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 KKK26277.1 - 0.0048 16.8 0.3 0.11 12.4 0.0 2.8 3 0 0 3 3 3 1 NACHT domain AAA_3 PF07726.11 KKK26277.1 - 0.0049 16.7 0.0 0.014 15.2 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.13 KKK26277.1 - 0.0056 15.9 0.0 0.011 15.0 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_28 PF13521.6 KKK26277.1 - 0.0077 16.5 0.0 0.018 15.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 KKK26277.1 - 0.0078 15.6 0.0 0.018 14.4 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 KKK26277.1 - 0.0085 15.8 0.1 0.23 11.1 0.0 2.5 2 1 0 2 2 2 1 Sigma-54 interaction domain TniB PF05621.11 KKK26277.1 - 0.011 15.2 0.0 0.54 9.6 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein AAA_30 PF13604.6 KKK26277.1 - 0.012 15.4 0.8 0.03 14.0 0.1 2.1 2 1 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KKK26277.1 - 0.012 15.4 0.0 0.024 14.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KKK26277.1 - 0.018 14.8 0.1 0.051 13.3 0.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_11 PF13086.6 KKK26277.1 - 0.042 13.6 0.1 0.13 12.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 KKK26277.1 - 0.061 13.2 1.6 0.38 10.6 0.1 2.6 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea Bac_DnaA PF00308.18 KKK26277.1 - 0.065 13.1 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Bacterial dnaA protein AAA_23 PF13476.6 KKK26277.1 - 0.091 13.3 0.2 2.7 8.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KKK26277.1 - 0.093 12.0 0.1 0.24 10.7 0.0 1.7 2 0 0 2 2 1 0 Zeta toxin ATPase PF06745.13 KKK26277.1 - 0.11 11.8 0.4 0.56 9.5 0.0 2.2 3 0 0 3 3 2 0 KaiC AAA_25 PF13481.6 KKK26277.1 - 0.13 11.8 1.7 0.22 11.1 0.1 2.1 2 1 1 3 3 3 0 AAA domain AAA_29 PF13555.6 KKK26277.1 - 0.13 12.0 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_19 PF13245.6 KKK26277.1 - 0.13 12.5 0.1 0.4 11.0 0.1 1.8 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KKK26277.1 - 0.14 12.6 0.1 0.56 10.7 0.0 2.1 2 0 0 2 2 2 0 ABC transporter Viral_Hsp90 PF03225.14 KKK26277.1 - 0.15 10.5 0.0 0.24 9.8 0.0 1.2 1 0 0 1 1 1 0 Viral heat shock protein Hsp90 homologue Parvo_NS1 PF01057.17 KKK26277.1 - 0.2 10.7 0.0 0.37 9.8 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Asp PF00026.23 KKK26278.1 - 9.9e-109 363.6 0.0 1.5e-108 363.0 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KKK26278.1 - 2.8e-16 60.3 1.6 8.3e-14 52.2 1.6 2.6 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KKK26278.1 - 2.9e-05 24.6 0.1 0.38 11.4 0.0 3.3 2 2 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.6 KKK26278.1 - 0.00033 20.5 0.0 0.0025 17.6 0.0 2.1 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.6 KKK26278.1 - 0.0025 18.3 0.0 5.5 7.6 0.0 3.2 3 1 0 3 3 3 2 gag-polyprotein putative aspartyl protease NIF PF03031.18 KKK26279.1 - 6e-26 91.1 0.1 1.9e-25 89.5 0.0 1.8 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase BRCT PF00533.26 KKK26279.1 - 1.8e-07 31.4 0.0 4.5e-07 30.2 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 KKK26279.1 - 0.00018 21.9 0.1 0.0017 18.7 0.0 2.4 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain PTCB-BRCT PF12738.7 KKK26279.1 - 0.0019 18.1 0.2 0.0044 16.9 0.2 1.6 1 0 0 1 1 1 1 twin BRCT domain BRCT_3 PF18428.1 KKK26279.1 - 0.0034 17.4 0.0 0.011 15.8 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain RTT107_BRCT_5 PF16770.5 KKK26279.1 - 0.0041 17.0 0.0 0.011 15.6 0.0 1.7 1 0 0 1 1 1 1 Regulator of Ty1 transposition protein 107 BRCT domain Aft1_HRA PF11786.8 KKK26280.1 - 7.4e-26 90.3 7.9 7.4e-26 90.3 7.9 2.8 3 0 0 3 3 3 1 Aft1 HRA domain Aft1_HRR PF11787.8 KKK26280.1 - 4.4e-23 82.2 2.3 4.4e-23 82.2 2.3 3.3 3 1 0 3 3 3 1 Aft1 HRR domain Aft1_OSA PF11785.8 KKK26280.1 - 1.1e-20 73.8 10.3 2.5e-20 72.7 7.6 2.8 2 0 0 2 2 2 1 Aft1 osmotic stress response (OSM) domain bZIP_1 PF00170.21 KKK26280.1 - 8.1e-13 48.3 4.7 1.6e-12 47.4 4.7 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KKK26280.1 - 1.8e-05 24.7 5.0 4.2e-05 23.6 5.0 1.6 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 KKK26280.1 - 0.0096 16.4 2.3 0.0096 16.4 2.3 1.9 1 1 1 2 2 2 1 bZIP Maf transcription factor Transthyretin PF00576.21 KKK26281.1 - 2.2e-33 115.2 0.0 2.9e-33 114.8 0.0 1.2 1 0 0 1 1 1 1 HIUase/Transthyretin family MG4 PF17789.1 KKK26281.1 - 0.16 12.1 0.0 0.33 11.1 0.0 1.5 1 0 0 1 1 1 0 Macroglobulin domain MG4 Exo70 PF03081.15 KKK26283.1 - 0.032 13.3 4.3 0.13 11.3 0.4 2.1 2 0 0 2 2 2 0 Exo70 exocyst complex subunit Syntaxin_2 PF14523.6 KKK26283.1 - 0.2 12.0 1.4 0.68 10.3 0.2 2.3 2 0 0 2 2 2 0 Syntaxin-like protein AATF-Che1 PF13339.6 KKK26283.1 - 0.76 10.5 10.9 0.21 12.3 2.4 3.0 2 1 0 2 2 2 0 Apoptosis antagonizing transcription factor GatB_N PF02934.15 KKK26285.1 - 3.5e-96 321.8 0.0 5.4e-96 321.2 0.0 1.3 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.18 KKK26285.1 - 3.2e-26 92.0 0.0 6.7e-26 90.9 0.0 1.5 1 0 0 1 1 1 1 GatB domain NB-ARC PF00931.22 KKK26286.1 - 7.5e-13 48.3 0.0 1.2e-12 47.6 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.6 KKK26286.1 - 0.00021 21.6 0.0 0.00046 20.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KKK26286.1 - 0.0019 18.6 0.0 0.0047 17.3 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain ATPase PF06745.13 KKK26286.1 - 0.0039 16.6 0.1 0.013 14.9 0.0 1.7 2 0 0 2 2 2 1 KaiC AAA_33 PF13671.6 KKK26286.1 - 0.004 17.3 0.0 0.011 15.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 KKK26286.1 - 0.033 13.5 0.0 0.11 11.7 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin RuvB_N PF05496.12 KKK26286.1 - 0.033 13.9 0.0 0.063 13.0 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain DUF397 PF04149.12 KKK26286.1 - 0.035 14.2 0.2 0.11 12.6 0.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF397) NACHT PF05729.12 KKK26286.1 - 0.043 13.7 0.0 0.091 12.7 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_18 PF13238.6 KKK26286.1 - 0.17 12.4 0.0 0.39 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain Abhydrolase_6 PF12697.7 KKK26287.1 - 5.5e-06 27.1 0.0 8.6e-06 26.5 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.14 KKK26287.1 - 2.6e-05 23.9 0.1 6.3e-05 22.6 0.0 1.5 1 1 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 KKK26287.1 - 0.00019 21.3 0.0 0.00029 20.6 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Cutinase PF01083.22 KKK26287.1 - 0.099 12.6 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Cutinase Abhydrolase_8 PF06259.12 KKK26287.1 - 0.13 11.9 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase ECH_1 PF00378.20 KKK26288.1 - 6.8e-39 133.7 0.0 1.4e-38 132.6 0.0 1.5 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KKK26288.1 - 1e-27 97.5 0.0 1.2e-27 97.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Arginase PF00491.21 KKK26289.1 - 9.4e-73 245.1 0.1 1.1e-72 244.9 0.1 1.0 1 0 0 1 1 1 1 Arginase family MARVEL PF01284.23 KKK26290.1 - 0.0038 17.3 19.0 0.0058 16.7 19.0 1.3 1 0 0 1 1 1 1 Membrane-associating domain Lyase_1 PF00206.20 KKK26291.1 - 4.4e-89 299.0 0.0 6e-89 298.5 0.0 1.2 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.6 KKK26291.1 - 6.5e-23 81.3 0.1 2.9e-22 79.2 0.0 2.1 2 0 0 2 2 2 1 Argininosuccinate lyase C-terminal Put_DNA-bind_N PF06971.13 KKK26293.1 - 0.053 13.5 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 Putative DNA-binding protein N-terminus CRM1_C PF08767.11 KKK26294.1 - 2.2e-11 43.5 0.1 2.4e-11 43.4 0.1 1.0 1 0 0 1 1 1 1 CRM1 C terminal GTP_EFTU_D3 PF03143.17 KKK26294.1 - 6.8e-07 29.6 0.1 8.3e-07 29.3 0.1 1.1 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain Med17 PF10156.9 KKK26295.1 - 1.2e-99 334.2 0.0 1.7e-99 333.6 0.0 1.1 1 0 0 1 1 1 1 Subunit 17 of Mediator complex DAO PF01266.24 KKK26296.1 - 9.2e-46 157.0 0.3 1.1e-45 156.8 0.3 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Amino_oxidase PF01593.24 KKK26296.1 - 0.00037 19.9 1.3 1.2 8.4 0.0 3.7 3 1 1 4 4 4 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KKK26296.1 - 0.00099 19.3 0.9 0.0026 17.9 0.9 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KKK26296.1 - 0.002 17.4 0.0 0.11 11.7 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KKK26296.1 - 0.0027 17.7 0.1 0.22 11.5 0.1 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 KKK26296.1 - 0.0058 15.9 0.0 0.0087 15.3 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KKK26296.1 - 0.042 12.9 0.6 0.065 12.3 0.6 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.27 KKK26296.1 - 0.073 13.6 0.0 0.27 11.8 0.1 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KKK26296.1 - 0.19 10.9 0.1 0.33 10.2 0.1 1.3 1 0 0 1 1 1 0 Thi4 family CorA PF01544.18 KKK26297.1 - 6e-45 153.8 0.0 8e-45 153.4 0.0 1.1 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein MFS_1 PF07690.16 KKK26298.1 - 1e-36 126.6 25.9 1e-36 126.6 25.9 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 KKK26298.1 - 6.5e-07 29.0 7.1 6.5e-07 29.0 7.1 2.8 1 1 1 2 2 2 1 Uncharacterised MFS-type transporter YbfB adh_short PF00106.25 KKK26299.1 - 8.3e-27 93.9 0.3 1.2e-26 93.4 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KKK26299.1 - 1e-23 84.1 0.0 1.3e-23 83.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KKK26299.1 - 2.5e-05 24.3 0.1 5.4e-05 23.2 0.1 1.6 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KKK26299.1 - 0.0026 17.7 0.1 0.0055 16.6 0.1 1.6 1 1 0 1 1 1 1 NAD(P)H-binding DUF4831 PF16115.5 KKK26299.1 - 0.029 13.4 0.0 0.25 10.4 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4831) DUF5401 PF17380.2 KKK26299.1 - 0.17 9.9 0.0 0.22 9.5 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) DUF1776 PF08643.10 KKK26299.1 - 0.2 11.0 0.0 0.31 10.4 0.0 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Glyco_hydro_76 PF03663.14 KKK26301.1 - 6.9e-158 525.9 23.3 1e-157 525.4 23.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 ADH_N PF08240.12 KKK26301.1 - 1.6e-25 89.1 0.3 1.8e-24 85.7 0.1 2.5 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KKK26301.1 - 3.6e-21 75.5 1.5 7.6e-21 74.4 1.5 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KKK26301.1 - 4.6e-06 27.7 0.1 9.9e-06 26.6 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Ig_GlcNase PF18368.1 KKK26302.1 - 6.8e-30 103.3 1.1 1.7e-29 102.1 0.2 2.1 2 0 0 2 2 2 1 Exo-beta-D-glucosaminidase Ig-fold domain Glyco_hydro_2 PF00703.21 KKK26302.1 - 2.7e-12 47.3 0.6 6.3e-12 46.2 0.0 2.0 3 0 0 3 3 3 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.18 KKK26302.1 - 0.0036 17.2 0.0 0.0073 16.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.17 KKK26302.1 - 0.012 14.7 0.0 0.019 14.1 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain Ig_mannosidase PF17753.1 KKK26302.1 - 0.052 13.3 0.0 0.14 11.9 0.0 1.7 1 0 0 1 1 1 0 Ig-fold domain Mannosidase_ig PF17786.1 KKK26302.1 - 0.18 12.5 0.7 1.7 9.3 0.0 2.4 1 1 1 2 2 2 0 Mannosidase Ig/CBM-like domain F-box-like PF12937.7 KKK26303.1 - 0.00087 19.1 1.3 0.013 15.4 0.2 2.6 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KKK26303.1 - 0.0016 18.3 0.2 0.0052 16.6 0.2 1.9 1 0 0 1 1 1 1 F-box domain p450 PF00067.22 KKK26304.1 - 5.2e-76 256.2 0.0 7.6e-76 255.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.18 KKK26304.1 - 1.4e-05 24.3 0.2 2.4e-05 23.5 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain PAP2_3 PF14378.6 KKK26306.1 - 2.1e-23 83.0 14.5 1.1e-16 61.1 1.2 2.5 2 0 0 2 2 2 2 PAP2 superfamily ABC2_membrane_2 PF12679.7 KKK26306.1 - 0.14 11.4 3.9 0.26 10.5 3.9 1.5 1 0 0 1 1 1 0 ABC-2 family transporter protein PAP2 PF01569.21 KKK26306.1 - 5.4 6.8 10.3 6.8 6.5 8.2 2.2 2 1 0 2 2 2 0 PAP2 superfamily Sugar_tr PF00083.24 KKK26307.1 - 1.1e-28 100.4 26.1 2.6e-18 66.1 6.1 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KKK26307.1 - 2.3e-19 69.5 59.7 3.4e-17 62.4 36.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily ATG22 PF11700.8 KKK26307.1 - 0.0096 14.6 12.0 0.35 9.4 0.2 3.4 3 0 0 3 3 3 3 Vacuole effluxer Atg22 like Zn_clus PF00172.18 KKK26308.1 - 2.1e-08 34.1 14.0 3.9e-08 33.3 14.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Methyltransf_25 PF13649.6 KKK26309.1 - 2.5e-16 60.2 0.0 5.2e-16 59.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KKK26309.1 - 1.3e-15 57.8 0.0 3.4e-15 56.5 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KKK26309.1 - 6.7e-13 49.2 0.0 1.1e-12 48.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KKK26309.1 - 1.5e-10 41.0 0.0 2.5e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KKK26309.1 - 1.6e-07 31.3 0.0 2.7e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KKK26309.1 - 0.006 15.9 0.0 0.0089 15.3 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.14 KKK26309.1 - 0.12 12.0 0.0 0.4 10.2 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_9 PF08003.11 KKK26309.1 - 0.22 10.4 0.0 0.31 9.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) GFA PF04828.14 KKK26310.1 - 7.6e-21 74.3 5.2 9.9e-21 73.9 5.2 1.1 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme DUF2688 PF10892.8 KKK26310.1 - 0.12 11.9 5.7 1.6 8.3 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2688) NAD_binding_1 PF00175.21 KKK26311.1 - 1.1e-13 51.8 0.0 2.1e-13 50.9 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Globin PF00042.22 KKK26311.1 - 8e-10 39.3 0.2 2.9e-09 37.5 0.1 2.0 2 0 0 2 2 2 1 Globin NAD_binding_6 PF08030.12 KKK26311.1 - 1.5e-07 31.7 0.0 1.9e-06 28.0 0.0 2.2 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_6 PF00970.24 KKK26311.1 - 1.3e-06 28.7 0.0 2.3e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Protoglobin PF11563.8 KKK26311.1 - 8.2e-05 22.6 0.1 0.00016 21.6 0.1 1.4 1 0 0 1 1 1 1 Protoglobin CIA30 PF08547.12 KKK26312.1 - 3.9e-40 137.5 0.0 4.4e-40 137.3 0.0 1.0 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) Sugar_tr PF00083.24 KKK26313.1 - 1.4e-22 80.2 26.2 1.5e-20 73.5 26.2 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKK26313.1 - 3.9e-06 26.0 37.8 6.2e-05 22.1 11.5 3.1 1 1 2 3 3 2 2 Major Facilitator Superfamily DUF2333 PF10095.9 KKK26313.1 - 0.11 11.5 0.0 0.19 10.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2333) MFS_1 PF07690.16 KKK26314.1 - 4.1e-31 108.2 18.4 4.1e-31 108.2 18.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily YpmT PF17431.2 KKK26314.1 - 0.8 9.8 2.8 1.1 9.4 0.0 2.7 2 1 1 3 3 3 0 Uncharacterized YmpT-like Amino_oxidase PF01593.24 KKK26315.1 - 6.3e-52 177.4 0.0 1.4e-51 176.2 0.0 1.5 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KKK26315.1 - 1.3e-15 57.3 0.2 2.5e-15 56.5 0.2 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KKK26315.1 - 1e-07 31.5 0.0 1.9e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KKK26315.1 - 2.9e-06 27.7 0.2 7.3e-06 26.5 0.2 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KKK26315.1 - 3e-06 26.2 0.4 4.3e-06 25.7 0.4 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_3 PF01494.19 KKK26315.1 - 1.3e-05 24.7 0.9 2.5e-05 23.7 0.9 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.24 KKK26315.1 - 1.6e-05 24.1 1.6 2.7e-05 23.5 1.6 1.3 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.21 KKK26315.1 - 2.6e-05 23.6 0.1 4.2e-05 22.9 0.1 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.7 KKK26315.1 - 0.00015 21.3 0.4 0.00022 20.7 0.4 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.24 KKK26315.1 - 0.00035 20.3 3.9 0.00056 19.6 2.9 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 KKK26315.1 - 0.00049 19.3 0.5 0.00074 18.7 0.5 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Thi4 PF01946.17 KKK26315.1 - 0.00085 18.6 0.1 0.0022 17.3 0.1 1.6 2 0 0 2 2 2 1 Thi4 family Glu_dehyd_C PF16912.5 KKK26315.1 - 0.0019 17.8 0.0 0.0036 16.8 0.0 1.4 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus YjeF_N PF03853.15 KKK26315.1 - 0.0051 16.7 0.0 0.0084 16.0 0.0 1.3 1 0 0 1 1 1 1 YjeF-related protein N-terminus Lycopene_cycl PF05834.12 KKK26315.1 - 0.012 14.6 0.3 0.018 14.1 0.3 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_3 PF13738.6 KKK26315.1 - 0.042 13.1 0.1 0.069 12.4 0.1 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KKK26315.1 - 0.057 12.3 0.4 0.095 11.5 0.4 1.3 1 0 0 1 1 1 0 Tryptophan halogenase Abhydrolase_6 PF12697.7 KKK26315.1 - 0.063 13.9 0.2 0.38 11.3 0.1 2.0 2 0 0 2 2 2 0 Alpha/beta hydrolase family 3HCDH_N PF02737.18 KKK26315.1 - 0.079 12.8 0.2 0.13 12.1 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF1188 PF06690.11 KKK26315.1 - 0.11 12.0 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1188) Shikimate_DH PF01488.20 KKK26315.1 - 0.14 12.2 0.3 0.35 10.9 0.1 1.8 2 0 0 2 2 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 KKK26315.1 - 0.34 11.4 2.1 0.37 11.3 0.8 1.9 2 1 0 2 2 1 0 Putative NAD(P)-binding FA_hydroxylase PF04116.13 KKK26316.1 - 1.9e-22 80.1 8.5 1.9e-22 80.1 8.5 2.1 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily MscL PF01741.18 KKK26317.1 - 7.1e-13 48.9 0.0 7.8e-13 48.8 0.0 1.1 1 0 0 1 1 1 1 Large-conductance mechanosensitive channel, MscL Cutinase PF01083.22 KKK26319.1 - 7.9e-40 136.7 0.1 1.2e-39 136.1 0.1 1.2 1 0 0 1 1 1 1 Cutinase Abhydrolase_2 PF02230.16 KKK26319.1 - 0.0022 17.9 0.0 0.0038 17.0 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 KKK26319.1 - 0.0045 16.3 0.0 0.0074 15.6 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PE-PPE PF08237.11 KKK26319.1 - 0.0047 16.5 0.0 0.0075 15.8 0.0 1.3 1 0 0 1 1 1 1 PE-PPE domain DUF3430 PF11912.8 KKK26320.1 - 0.052 13.6 0.0 0.062 13.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3430) Sugar_tr PF00083.24 KKK26321.1 - 6.1e-133 444.0 20.8 7e-133 443.8 20.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKK26321.1 - 7.3e-22 77.8 36.2 1.1e-11 44.3 11.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF962 PF06127.11 KKK26321.1 - 0.22 11.6 0.0 0.22 11.6 0.0 2.3 3 1 0 3 3 3 0 Protein of unknown function (DUF962) Glyco_hydro_3_C PF01915.22 KKK26322.1 - 1.4e-51 175.3 0.0 2.3e-51 174.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KKK26322.1 - 1.6e-45 155.9 0.0 2.6e-45 155.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KKK26322.1 - 9.6e-27 92.9 0.1 2.3e-26 91.7 0.1 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain Amidase PF01425.21 KKK26323.1 - 3.4e-89 299.9 0.0 1.4e-88 297.8 0.0 1.8 1 1 0 1 1 1 1 Amidase ThuA PF06283.11 KKK26324.1 - 0.12 12.6 0.0 0.15 12.2 0.0 1.3 1 0 0 1 1 1 0 Trehalose utilisation DUF853 PF05872.12 KKK26324.1 - 0.17 10.5 0.0 0.23 10.0 0.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) Aldedh PF00171.22 KKK26325.1 - 3.4e-07 29.1 0.0 4e-07 28.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family SAC3_GANP PF03399.16 KKK26326.1 - 3.5e-26 92.3 0.8 3.4e-14 52.9 0.1 2.1 1 1 1 2 2 2 2 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 KKK26326.1 - 0.00037 20.5 0.0 0.00088 19.3 0.0 1.6 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family TPR_MalT PF17874.1 KKK26326.1 - 0.013 14.9 0.2 0.023 14.1 0.2 1.3 1 0 0 1 1 1 0 MalT-like TPR region Chitin_synth_1 PF01644.17 KKK26327.1 - 2.2e-78 261.8 0.1 3.3e-78 261.3 0.1 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 KKK26327.1 - 1.7e-28 98.4 0.2 3.6e-28 97.3 0.2 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 KKK26327.1 - 4.7e-21 75.0 0.3 8e-19 67.6 0.0 2.5 2 0 0 2 2 2 1 Chitin synthase Glyco_trans_2_3 PF13632.6 KKK26327.1 - 9.7e-07 28.9 0.2 9.7e-07 28.9 0.2 1.9 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KKK26327.1 - 0.026 14.4 0.0 0.12 12.2 0.0 2.1 2 1 1 3 3 3 0 Glycosyltransferase like family 2 YesK PF14150.6 KKK26327.1 - 7.1 6.9 8.6 0.86 9.8 3.7 2.1 2 0 0 2 2 2 0 YesK-like protein Metallophos PF00149.28 KKK26329.1 - 4.5e-35 122.0 0.0 5e-34 118.6 0.0 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Glyco_hydro_65N PF03636.15 KKK26329.1 - 0.099 12.3 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain Sugar_tr PF00083.24 KKK26330.1 - 1.2e-60 205.7 13.0 1.5e-60 205.3 13.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKK26330.1 - 5.3e-19 68.4 47.2 4.6e-16 58.7 22.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KKK26330.1 - 0.00054 18.6 7.6 0.00054 18.6 7.6 3.1 2 1 1 3 3 3 1 MFS/sugar transport protein C_GCAxxG_C_C PF09719.10 KKK26330.1 - 0.13 12.5 0.1 4.8 7.5 0.1 2.7 2 0 0 2 2 2 0 Putative redox-active protein (C_GCAxxG_C_C) SUIM_assoc PF16619.5 KKK26330.1 - 0.29 11.2 4.4 0.52 10.4 4.4 1.4 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Aldedh PF00171.22 KKK26331.1 - 2.9e-187 622.8 0.3 3.2e-187 622.6 0.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Mre11_DNA_bind PF04152.14 KKK26332.1 - 5.9e-56 189.4 0.8 5.9e-56 189.4 0.8 2.3 3 0 0 3 3 3 1 Mre11 DNA-binding presumed domain Metallophos PF00149.28 KKK26332.1 - 2.6e-13 50.9 2.1 6.7e-13 49.6 1.7 1.8 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KKK26332.1 - 0.00069 19.8 0.0 0.0063 16.7 0.0 2.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain FmdE PF02663.14 KKK26332.1 - 0.19 11.8 1.7 0.28 11.2 0.2 2.2 2 0 0 2 2 2 0 FmdE, Molybdenum formylmethanofuran dehydrogenase operon Smg4_UPF3 PF03467.15 KKK26333.1 - 2.4e-37 128.6 0.0 2.4e-37 128.6 0.0 2.8 3 0 0 3 3 3 1 Smg-4/UPF3 family RRM_1 PF00076.22 KKK26333.1 - 4.5e-09 36.0 0.2 4.6e-07 29.6 0.0 3.1 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KKK26333.1 - 0.038 14.0 0.1 0.12 12.4 0.0 1.8 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Pep1_7 PF17232.2 KKK26333.1 - 0.094 13.2 0.2 0.094 13.2 0.2 2.8 3 0 0 3 3 3 0 Elicitor peptide 1-7 NUDIX PF00293.28 KKK26334.1 - 1.4e-13 51.0 1.5 2.7e-12 46.8 1.5 2.1 1 1 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 KKK26334.1 - 0.13 12.3 0.1 1.2 9.2 0.1 2.3 1 1 0 1 1 1 0 NUDIX domain Wyosine_form PF08608.12 KKK26335.1 - 1.2e-24 86.5 0.0 2.6e-24 85.3 0.0 1.7 1 0 0 1 1 1 1 Wyosine base formation Radical_SAM PF04055.21 KKK26335.1 - 9.5e-21 74.9 0.1 3.2e-20 73.2 0.1 1.9 1 1 0 1 1 1 1 Radical SAM superfamily Flavodoxin_1 PF00258.25 KKK26335.1 - 1.8e-09 38.0 1.0 7.3e-07 29.5 1.0 2.6 1 1 0 1 1 1 1 Flavodoxin Glyco_hydro_72 PF03198.14 KKK26336.1 - 3.7e-127 423.9 0.4 4.8e-127 423.6 0.4 1.1 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.18 KKK26336.1 - 5.5e-05 22.7 0.2 0.0096 15.4 0.0 2.3 2 0 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Phage_Gp17 PF17549.2 KKK26336.1 - 0.12 12.4 0.0 0.27 11.3 0.0 1.5 1 0 0 1 1 1 0 Gene Product 17 RAP1 PF07218.11 KKK26336.1 - 3.4 5.8 10.1 4.1 5.6 6.8 2.1 2 0 0 2 2 2 0 Rhoptry-associated protein 1 (RAP-1) F-box-like PF12937.7 KKK26337.1 - 4.3e-10 39.3 0.2 8.9e-10 38.3 0.2 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KKK26337.1 - 1.7e-09 37.3 0.8 4.5e-09 36.0 0.3 2.0 2 0 0 2 2 2 1 F-box domain F-box_4 PF15966.5 KKK26337.1 - 0.0088 15.9 0.0 0.019 14.9 0.0 1.5 1 0 0 1 1 1 1 F-box DUF2014 PF09427.10 KKK26337.1 - 0.13 11.6 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2014) UIM PF02809.20 KKK26337.1 - 6.6 6.9 5.3 24 5.2 0.1 3.3 3 0 0 3 3 3 0 Ubiquitin interaction motif AMP-binding PF00501.28 KKK26338.1 - 1e-74 251.7 0.0 1.2e-74 251.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KKK26338.1 - 4e-14 53.3 3.2 4.4e-14 53.2 1.3 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ABC_tran PF00005.27 KKK26339.1 - 1.8e-24 86.8 0.0 1.4e-12 48.3 0.0 3.1 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KKK26339.1 - 1.5e-11 44.7 1.8 0.0017 18.2 0.1 3.3 3 0 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 KKK26339.1 - 2.5e-05 24.4 0.0 0.14 12.4 0.0 2.7 2 0 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 KKK26339.1 - 0.013 15.2 0.0 0.031 14.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 KKK26339.1 - 0.028 14.9 0.4 0.056 13.9 0.4 1.5 1 0 0 1 1 1 0 AAA domain Ploopntkinase1 PF18748.1 KKK26339.1 - 0.028 13.9 0.0 0.089 12.3 0.0 1.7 2 0 0 2 2 2 0 P-loop Nucleotide Kinase1 NB-ARC PF00931.22 KKK26339.1 - 0.031 13.5 0.0 2.7 7.1 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain AAA_28 PF13521.6 KKK26339.1 - 0.058 13.6 0.1 0.2 11.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 KKK26339.1 - 0.11 12.8 0.1 1 9.7 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain NACHT PF05729.12 KKK26339.1 - 0.16 11.9 0.0 0.4 10.6 0.0 1.7 1 0 0 1 1 1 0 NACHT domain DUF3584 PF12128.8 KKK26339.1 - 0.17 9.4 0.2 0.24 8.9 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) SR-25 PF10500.9 KKK26339.1 - 0.37 10.4 17.2 0.75 9.4 17.2 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Exo84_C PF16528.5 KKK26340.1 - 1.4e-69 234.0 0.2 1.4e-69 234.0 0.2 1.9 2 0 0 2 2 2 1 Exocyst component 84 C-terminal Vps51 PF08700.11 KKK26340.1 - 4.1e-18 65.3 2.0 1.1e-17 63.8 2.0 1.8 1 0 0 1 1 1 1 Vps51/Vps67 Tub PF01167.18 KKK26340.1 - 0.23 11.2 1.4 0.27 11.0 0.3 1.5 2 0 0 2 2 2 0 Tub family HIP1_clath_bdg PF16515.5 KKK26340.1 - 3.2 8.4 8.4 0.39 11.4 2.5 2.4 3 0 0 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 MAS20 PF02064.15 KKK26341.1 - 2.2e-41 141.0 1.0 2.1e-27 95.8 0.3 2.0 2 0 0 2 2 2 2 MAS20 protein import receptor betaPIX_CC PF16523.5 KKK26341.1 - 0.0058 16.4 0.8 0.0093 15.8 0.8 1.3 1 0 0 1 1 1 1 betaPIX coiled coil PhoU PF01895.19 KKK26341.1 - 0.14 12.6 0.2 0.29 11.6 0.2 1.5 1 0 0 1 1 1 0 PhoU domain Abhydrolase_3 PF07859.13 KKK26342.1 - 8.9e-39 133.5 0.0 1.1e-38 133.2 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KKK26342.1 - 9.9e-06 25.2 0.0 0.0021 17.6 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family COesterase PF00135.28 KKK26342.1 - 0.00022 20.3 0.0 0.00083 18.3 0.0 1.7 1 1 0 1 1 1 1 Carboxylesterase family DLH PF01738.18 KKK26342.1 - 0.0077 15.8 0.0 0.22 11.0 0.0 2.1 2 0 0 2 2 2 1 Dienelactone hydrolase family Peptidase_S15 PF02129.18 KKK26342.1 - 0.016 14.8 0.0 1.3 8.6 0.0 2.4 3 0 0 3 3 3 0 X-Pro dipeptidyl-peptidase (S15 family) AXE1 PF05448.12 KKK26342.1 - 0.021 13.5 0.1 1.3 7.6 0.0 2.4 3 0 0 3 3 3 0 Acetyl xylan esterase (AXE1) Fungal_trans PF04082.18 KKK26343.1 - 4.6e-08 32.4 0.2 7.6e-08 31.7 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK26343.1 - 3.3e-06 27.1 8.8 5.9e-06 26.3 8.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain LSM PF01423.22 KKK26344.1 - 2.9e-16 58.9 0.1 4.3e-16 58.3 0.1 1.3 1 0 0 1 1 1 1 LSM domain WH2 PF02205.20 KKK26345.1 - 2.8e-10 39.7 1.1 7.4e-10 38.3 1.1 1.8 1 0 0 1 1 1 1 WH2 motif DUF5529 PF17669.1 KKK26346.1 - 0.025 14.6 0.9 0.056 13.5 0.3 1.7 1 1 1 2 2 2 0 Family of unknown function (DUF5529) Use1 PF09753.9 KKK26346.1 - 0.12 12.1 0.5 0.18 11.5 0.5 1.2 1 0 0 1 1 1 0 Membrane fusion protein Use1 DUF4336 PF14234.6 KKK26346.1 - 0.14 11.3 0.0 0.2 10.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4336) IU_nuc_hydro PF01156.19 KKK26347.1 - 2.2e-57 194.9 0.0 3.1e-57 194.5 0.0 1.1 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase SURF4 PF02077.15 KKK26349.1 - 4e-94 315.2 8.5 4.5e-94 315.0 8.5 1.0 1 0 0 1 1 1 1 SURF4 family UPF0139 PF03669.13 KKK26349.1 - 0.28 11.1 1.4 1.3 9.0 1.1 2.2 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0139) Ribosomal_L1 PF00687.21 KKK26351.1 - 1.3e-47 162.2 0.3 1.5e-47 162.0 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family SNF PF00209.18 KKK26351.1 - 0.026 13.2 0.1 0.036 12.8 0.1 1.1 1 0 0 1 1 1 0 Sodium:neurotransmitter symporter family FMO-like PF00743.19 KKK26352.1 - 9.8e-13 47.4 0.0 3.2e-12 45.7 0.0 1.8 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KKK26352.1 - 6e-12 45.4 0.0 1.6e-07 30.9 0.0 3.0 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KKK26352.1 - 2.3e-08 34.2 0.3 0.00016 21.7 0.0 3.4 3 0 0 3 3 3 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KKK26352.1 - 1.6e-06 28.2 0.1 8.9e-05 22.6 0.0 2.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KKK26352.1 - 3.4e-06 26.6 0.1 0.036 13.3 0.1 3.8 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KKK26352.1 - 1.3e-05 24.5 0.0 0.0064 15.7 0.0 3.3 3 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 KKK26352.1 - 0.0011 19.5 0.1 1.4 9.5 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KKK26352.1 - 0.083 12.1 0.5 0.16 11.2 0.0 1.6 2 0 0 2 2 2 0 Thi4 family AlaDh_PNT_C PF01262.21 KKK26352.1 - 0.19 11.0 0.0 3.3 6.9 0.0 2.2 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 KKK26352.1 - 0.19 10.9 0.9 0.39 9.9 0.1 1.8 2 0 0 2 2 2 0 FAD binding domain DUF3446 PF11928.8 KKK26352.1 - 0.79 10.1 16.5 0.06 13.7 8.2 2.6 2 0 0 2 2 2 0 Early growth response N-terminal domain SR-25 PF10500.9 KKK26352.1 - 4.3 6.9 15.4 0.16 11.5 9.5 1.6 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Arf PF00025.21 KKK26354.1 - 9.4e-80 266.2 0.1 1.1e-79 265.9 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KKK26354.1 - 5.5e-15 55.3 0.0 6.8e-15 55.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 KKK26354.1 - 3.2e-14 53.2 0.0 4.3e-14 52.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 KKK26354.1 - 2.3e-13 50.0 1.3 2e-09 37.1 0.3 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 KKK26354.1 - 5.2e-13 48.9 0.0 5.8e-13 48.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 KKK26354.1 - 2.5e-10 40.1 0.0 3.2e-10 39.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KKK26354.1 - 4.3e-06 26.8 0.0 6.4e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 KKK26354.1 - 0.011 15.1 0.4 0.022 14.1 0.4 1.7 1 1 0 1 1 1 0 6-phosphofructo-2-kinase Fungal_trans PF04082.18 KKK26355.1 - 2e-18 66.4 1.3 3.3e-18 65.7 1.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain CorA PF01544.18 KKK26356.1 - 0.0002 20.8 2.6 0.012 15.0 0.7 2.4 2 1 0 2 2 2 2 CorA-like Mg2+ transporter protein SieB PF14163.6 KKK26356.1 - 0.29 10.6 2.2 0.8 9.2 2.2 1.7 1 0 0 1 1 1 0 Super-infection exclusion protein B Septin PF00735.18 KKK26357.1 - 5.9e-104 347.3 0.0 1e-103 346.5 0.0 1.4 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 KKK26357.1 - 3.2e-05 24.0 0.0 7.9e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KKK26357.1 - 0.0021 17.6 0.1 0.16 11.5 0.0 2.3 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 KKK26357.1 - 0.0043 17.1 3.8 1 9.4 0.0 3.0 2 1 1 3 3 3 2 Dynamin family RsgA_GTPase PF03193.16 KKK26357.1 - 0.0069 16.3 3.3 0.012 15.6 0.2 2.6 3 1 0 3 3 3 1 RsgA GTPase AIG1 PF04548.16 KKK26357.1 - 0.11 11.8 0.1 0.27 10.5 0.1 1.7 1 1 0 1 1 1 0 AIG1 family zf-C2H2 PF00096.26 KKK26358.1 - 3.7e-07 30.2 10.9 0.00031 21.0 1.7 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KKK26358.1 - 0.00063 20.4 8.8 0.044 14.6 1.0 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger FOXP-CC PF16159.5 KKK26358.1 - 0.52 11.0 4.5 2.2 9.0 0.4 2.3 1 1 1 2 2 2 0 FOXP coiled-coil domain CHORD PF04968.12 KKK26358.1 - 0.92 10.3 5.0 12 6.7 0.6 2.5 1 1 1 2 2 2 0 CHORD zf-CGNR PF11706.8 KKK26358.1 - 1.2 9.1 4.9 0.7 9.8 0.9 2.3 2 0 0 2 2 2 0 CGNR zinc finger G_glu_transpept PF01019.21 KKK26359.1 - 1.7e-142 475.8 0.0 1.9e-142 475.6 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Glyco_tranf_2_3 PF13641.6 KKK26361.1 - 6.6e-32 111.2 0.1 9.1e-32 110.8 0.1 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KKK26361.1 - 2.6e-08 33.9 0.0 4.4e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 KKK26361.1 - 3.1e-08 33.3 0.0 2.3e-07 30.4 0.0 2.2 1 1 0 1 1 1 1 Glycosyl transferase family 21 Oxysterol_BP PF01237.18 KKK26362.1 - 2.3e-133 444.7 0.0 3.3e-132 440.9 0.0 2.2 2 0 0 2 2 2 1 Oxysterol-binding protein ATP12 PF07542.11 KKK26362.1 - 1.8e-47 160.7 1.4 4.1e-47 159.5 1.4 1.7 1 0 0 1 1 1 1 ATP12 chaperone protein Ank_5 PF13857.6 KKK26362.1 - 1.6e-12 47.4 0.1 4.2e-09 36.5 0.1 3.3 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KKK26362.1 - 6.2e-12 45.9 0.0 6.5e-08 33.1 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) PH PF00169.29 KKK26362.1 - 9.7e-11 42.1 0.6 2.2e-10 41.0 0.6 1.6 1 0 0 1 1 1 1 PH domain Ank PF00023.30 KKK26362.1 - 6.8e-09 35.8 0.0 0.0018 18.6 0.0 3.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 KKK26362.1 - 2.2e-08 33.7 0.0 0.0057 17.1 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 KKK26362.1 - 5.5e-08 33.2 0.0 0.00021 21.8 0.0 3.3 2 1 1 3 3 3 2 Ankyrin repeats (many copies) PH_8 PF15409.6 KKK26362.1 - 7.4e-07 29.4 0.9 2.1e-06 27.9 0.9 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 KKK26362.1 - 1.2e-05 25.7 4.3 4.2e-05 23.9 1.4 2.9 2 0 0 2 2 2 1 Pleckstrin homology domain XRN_M PF17846.1 KKK26362.1 - 0.045 12.7 1.5 0.09 11.7 1.5 1.5 1 0 0 1 1 1 0 Xrn1 helical domain LLC1 PF14945.6 KKK26362.1 - 0.15 12.6 6.8 0.25 11.9 0.6 3.0 2 0 0 2 2 2 0 Normal lung function maintenance, Low in Lung Cancer 1 protein MeaB PF03308.16 KKK26362.1 - 3.5 6.5 5.7 2.6 7.0 0.9 2.7 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB zf-Mss51 PF13824.6 KKK26363.1 - 4.2e-28 97.2 6.3 8e-28 96.3 6.3 1.5 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 zf-MYND PF01753.18 KKK26363.1 - 0.023 14.8 2.4 0.033 14.3 0.4 2.1 2 0 0 2 2 2 0 MYND finger zf-HIT PF04438.16 KKK26363.1 - 0.31 10.9 2.7 2 8.4 0.3 2.4 2 0 0 2 2 2 0 HIT zinc finger PhoLip_ATPase_C PF16212.5 KKK26364.1 - 7.3e-70 235.6 22.1 7.3e-70 235.6 22.1 2.2 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KKK26364.1 - 2.2e-24 84.9 1.9 2.9e-22 78.1 0.1 2.9 3 0 0 3 3 3 2 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 KKK26364.1 - 5.6e-14 52.9 1.4 2.7e-05 24.6 0.3 3.4 2 1 1 3 3 3 3 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 KKK26364.1 - 5.3e-11 42.4 0.0 5.3e-11 42.4 0.0 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase PF13246.6 KKK26364.1 - 3.3e-10 39.9 0.0 2.6e-09 37.1 0.0 2.4 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KKK26364.1 - 0.0007 19.4 0.3 0.0049 16.7 0.1 2.2 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF4404 PF14357.6 KKK26364.1 - 0.15 12.7 0.1 3.2 8.5 0.2 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) DUF1453 PF07301.11 KKK26364.1 - 2.7 8.0 6.5 2.4 8.2 2.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1453) MIS13 PF08202.11 KKK26365.1 - 1.3e-45 156.0 7.2 3.7e-44 151.2 7.2 2.3 1 1 0 1 1 1 1 Mis12-Mtw1 protein family TSC22 PF01166.18 KKK26365.1 - 0.024 14.9 0.3 0.072 13.4 0.3 1.7 1 0 0 1 1 1 0 TSC-22/dip/bun family DUF3216 PF11505.8 KKK26365.1 - 0.03 14.5 0.8 7.7 6.8 0.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3216) L_lactis_ph-MCP PF06673.11 KKK26365.1 - 0.036 13.0 0.2 0.065 12.2 0.2 1.3 1 0 0 1 1 1 0 Lactococcus lactis bacteriophage major capsid protein DivIC PF04977.15 KKK26365.1 - 0.33 10.7 3.3 0.86 9.4 3.3 1.7 1 0 0 1 1 1 0 Septum formation initiator AT_hook PF02178.19 KKK26365.1 - 0.61 10.2 11.9 6.2 7.0 0.6 3.6 2 0 0 2 2 2 0 AT hook motif HAUS6_N PF14661.6 KKK26365.1 - 1.7 8.2 7.6 12 5.4 0.1 2.8 2 1 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus PS_Dcarbxylase PF02666.15 KKK26366.1 - 3.4e-55 186.7 0.0 5e-55 186.2 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.30 KKK26366.1 - 6e-28 97.2 0.0 6.7e-17 61.7 0.0 2.5 2 0 0 2 2 2 2 C2 domain EF-hand_1 PF00036.32 KKK26366.1 - 0.017 14.7 0.1 0.055 13.0 0.1 2.0 1 0 0 1 1 1 0 EF hand DUF4681 PF15732.5 KKK26366.1 - 0.027 14.7 0.1 0.063 13.5 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4681) EF-hand_5 PF13202.6 KKK26366.1 - 0.064 12.8 0.0 0.17 11.4 0.0 1.8 1 0 0 1 1 1 0 EF hand EF-hand_6 PF13405.6 KKK26366.1 - 0.075 13.0 0.1 0.34 10.9 0.1 2.2 1 0 0 1 1 1 0 EF-hand domain EF-hand_7 PF13499.6 KKK26366.1 - 0.25 11.8 2.2 0.39 11.2 0.6 2.2 2 0 0 2 2 2 0 EF-hand domain pair Sugar_tr PF00083.24 KKK26367.1 - 4.3e-84 283.0 10.4 5e-84 282.8 10.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKK26367.1 - 2.1e-33 115.7 25.2 2.8e-33 115.3 25.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 KKK26367.1 - 2.1e-08 33.9 3.0 6.2e-08 32.3 3.0 1.7 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB TRI12 PF06609.13 KKK26367.1 - 0.0017 16.9 1.5 0.0017 16.9 1.5 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 KKK26367.1 - 0.027 12.8 4.1 0.024 12.9 1.5 2.2 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family ERO1 PF04137.15 KKK26368.1 - 8.8e-135 449.5 0.0 1.2e-134 449.0 0.0 1.2 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) P-II PF00543.22 KKK26368.1 - 0.2 12.3 0.0 0.36 11.4 0.0 1.3 1 0 0 1 1 1 0 Nitrogen regulatory protein P-II Defb50 PF17546.2 KKK26368.1 - 0.27 11.2 1.7 11 6.1 0.0 2.7 2 0 0 2 2 2 0 Beta defensin 50 Peroxin-13_N PF04088.13 KKK26369.1 - 1.4e-52 177.8 0.4 2.1e-52 177.2 0.4 1.3 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_2 PF07653.17 KKK26369.1 - 1.6e-09 37.3 0.0 3e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KKK26369.1 - 1.9e-08 33.8 0.0 3.2e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KKK26369.1 - 3.3e-06 26.9 0.1 5.5e-06 26.2 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain hSH3 PF14603.6 KKK26369.1 - 0.18 12.3 0.0 0.31 11.5 0.0 1.3 1 0 0 1 1 1 0 Helically-extended SH3 domain Pex2_Pex12 PF04757.14 KKK26369.1 - 0.19 11.3 0.0 0.3 10.7 0.0 1.3 1 0 0 1 1 1 0 Pex2 / Pex12 amino terminal region Podoplanin PF05808.11 KKK26370.1 - 0.00079 19.6 1.4 0.0011 19.1 1.4 1.3 1 0 0 1 1 1 1 Podoplanin SKG6 PF08693.10 KKK26370.1 - 0.0014 18.0 1.0 0.003 16.9 1.0 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain VSP PF03302.13 KKK26370.1 - 0.011 14.6 2.1 0.011 14.6 2.1 1.7 2 0 0 2 2 2 0 Giardia variant-specific surface protein Clr5 PF14420.6 KKK26371.1 - 7.5e-18 64.5 2.3 1.2e-17 63.8 2.3 1.4 1 0 0 1 1 1 1 Clr5 domain bZIP_2 PF07716.15 KKK26372.1 - 1e-12 47.9 11.9 1e-12 47.9 11.9 1.8 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.21 KKK26372.1 - 0.0021 18.1 8.6 0.0054 16.8 8.6 1.7 1 0 0 1 1 1 1 bZIP transcription factor EccE PF11203.8 KKK26372.1 - 0.044 14.1 0.9 0.08 13.3 0.9 1.5 1 0 0 1 1 1 0 Putative type VII ESX secretion system translocon, EccE TSC22 PF01166.18 KKK26372.1 - 0.95 9.8 4.0 0.58 10.5 1.3 2.1 2 0 0 2 2 2 0 TSC-22/dip/bun family Ndc1_Nup PF09531.10 KKK26372.1 - 1.4 7.5 7.4 2.1 7.0 7.4 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF2834 PF11196.8 KKK26373.1 - 0.0093 16.3 2.7 1.1 9.6 0.5 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF2834) DUF4834 PF16118.5 KKK26373.1 - 0.2 12.6 0.1 36 5.4 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) DUF974 PF06159.13 KKK26374.1 - 3.2e-79 266.2 0.0 3.8e-79 266.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF974) CENP-N PF05238.13 KKK26375.1 - 3.2e-154 514.2 0.0 3.6e-154 514.1 0.0 1.0 1 0 0 1 1 1 1 Kinetochore protein CHL4 like zf-RING_2 PF13639.6 KKK26376.1 - 7.5e-06 26.2 6.7 7.5e-06 26.2 6.7 1.9 2 0 0 2 2 2 1 Ring finger domain Prok-RING_1 PF14446.6 KKK26376.1 - 0.0003 20.6 1.6 0.0003 20.6 1.6 2.1 1 1 1 2 2 2 1 Prokaryotic RING finger family 1 zf-ANAPC11 PF12861.7 KKK26376.1 - 0.019 15.0 3.0 0.019 15.0 3.0 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Pox_A12 PF04651.13 KKK26376.1 - 0.075 13.1 0.0 0.12 12.5 0.0 1.2 1 0 0 1 1 1 0 Poxvirus A12 protein Zf_RING PF16744.5 KKK26376.1 - 0.13 12.4 2.8 0.24 11.5 1.9 1.9 2 0 0 2 2 2 0 KIAA1045 RING finger C1_1 PF00130.22 KKK26376.1 - 0.3 11.0 8.4 0.27 11.2 3.4 2.6 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) FANCL_C PF11793.8 KKK26376.1 - 0.31 11.2 10.4 0.2 11.8 7.4 2.1 2 1 0 2 2 2 0 FANCL C-terminal domain zf-RING_5 PF14634.6 KKK26376.1 - 0.99 9.4 11.5 0.11 12.5 6.4 2.0 2 0 0 2 2 2 0 zinc-RING finger domain zf-RING_4 PF14570.6 KKK26376.1 - 1 9.2 7.0 2.2 8.1 7.0 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.6 KKK26376.1 - 1.3 9.1 4.8 3.6 7.7 4.8 1.8 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KKK26376.1 - 1.4 8.9 5.2 2.9 7.8 5.2 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.7 KKK26376.1 - 1.6 8.9 9.3 4.1 7.6 9.3 1.7 1 0 0 1 1 1 0 RING-variant domain zf-RING_11 PF17123.5 KKK26376.1 - 4.5 7.1 8.9 0.62 9.9 3.3 2.2 2 0 0 2 2 2 0 RING-like zinc finger MARVEL PF01284.23 KKK26377.1 - 7.4e-31 107.1 11.8 8.4e-31 106.9 11.8 1.0 1 0 0 1 1 1 1 Membrane-associating domain TPT PF03151.16 KKK26378.1 - 2.8e-23 82.7 23.5 3.2e-23 82.5 23.5 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 KKK26378.1 - 5.9e-07 29.0 21.6 8e-07 28.5 21.6 1.2 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 KKK26378.1 - 0.0011 19.1 12.5 0.0011 19.1 12.5 2.3 2 0 0 2 2 2 1 EamA-like transporter family Gly_transf_sug PF04488.15 KKK26379.1 - 6.9e-14 52.3 0.1 1.1e-13 51.6 0.1 1.3 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.7 KKK26379.1 - 1.3 8.2 3.8 17 4.5 0.9 2.1 2 0 0 2 2 2 0 TcdA/TcdB catalytic glycosyltransferase domain MFS_1 PF07690.16 KKK26380.1 - 7.9e-23 80.9 40.0 2.9e-12 46.2 22.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KKK26380.1 - 5.7e-14 51.8 16.8 3e-12 46.2 2.2 2.7 1 1 0 2 2 2 2 Sugar (and other) transporter Fungal_trans PF04082.18 KKK26381.1 - 1.3e-29 103.0 1.5 7.7e-16 57.9 0.1 2.4 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK26381.1 - 7.8e-16 57.9 27.5 2.7e-09 37.0 11.1 2.5 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Streptin-Immun PF11083.8 KKK26381.1 - 1.4 9.4 2.9 25 5.3 0.3 2.5 2 0 0 2 2 2 0 Lantibiotic streptin immunity protein Glyco_trans_4_4 PF13579.6 KKK26381.1 - 3.8 7.9 7.2 1.6 9.2 2.0 2.5 2 0 0 2 2 2 0 Glycosyl transferase 4-like domain Glyco_hydro_28 PF00295.17 KKK26382.1 - 2.1e-28 99.4 4.1 2.1e-28 99.4 4.1 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 28 Pectate_lyase_3 PF12708.7 KKK26382.1 - 3.8e-10 40.0 4.3 3.8e-10 40.0 4.3 3.3 2 1 1 3 3 3 1 Pectate lyase superfamily protein UDPGP PF01704.18 KKK26383.1 - 1.6e-192 639.7 0.1 1.9e-192 639.5 0.1 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase PilO PF04350.13 KKK26383.1 - 0.016 15.4 0.2 0.073 13.2 0.0 2.1 3 0 0 3 3 3 0 Pilus assembly protein, PilO C2 PF00168.30 KKK26384.1 - 1.2e-67 224.7 0.0 8.7e-18 64.5 0.0 5.6 5 0 0 5 5 5 5 C2 domain SMP_LBD PF17047.5 KKK26384.1 - 0.00026 20.5 0.0 0.00044 19.8 0.0 1.4 1 0 0 1 1 1 1 Synaptotagmin-like mitochondrial-lipid-binding domain FKBP_C PF00254.28 KKK26384.1 - 0.026 14.8 0.0 0.15 12.4 0.0 2.3 2 0 0 2 2 2 0 FKBP-type peptidyl-prolyl cis-trans isomerase DUF92 PF01940.16 KKK26386.1 - 3.5e-83 278.6 11.0 4.2e-83 278.4 11.0 1.1 1 0 0 1 1 1 1 Integral membrane protein DUF92 Peptidase_A8 PF01252.18 KKK26386.1 - 0.057 13.6 2.0 0.28 11.4 0.2 2.3 1 1 0 2 2 2 0 Signal peptidase (SPase) II Amidohydro_1 PF01979.20 KKK26387.1 - 1.6e-12 47.4 0.0 1.9e-12 47.2 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KKK26387.1 - 0.0014 18.1 0.1 0.0087 15.6 0.0 2.0 2 0 0 2 2 2 1 Amidohydrolase family Methyltransf_33 PF10017.9 KKK26388.1 - 4.9e-83 278.8 0.0 6.7e-83 278.4 0.0 1.1 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent FGE-sulfatase PF03781.16 KKK26388.1 - 5.9e-22 78.5 1.8 5e-20 72.2 1.8 2.3 1 1 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.7 KKK26388.1 - 2.1e-07 31.5 0.0 2.6e-06 28.0 0.0 2.4 2 0 0 2 2 2 1 DinB superfamily Aldo_ket_red PF00248.21 KKK26389.1 - 3.9e-63 213.4 0.0 4.8e-63 213.1 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family SpoIIIAH PF12685.7 KKK26392.1 - 0.028 14.2 7.1 0.047 13.5 7.1 1.3 1 0 0 1 1 1 0 SpoIIIAH-like protein Apt1 PF10351.9 KKK26392.1 - 0.045 12.6 6.8 0.05 12.5 6.8 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain CPSF100_C PF13299.6 KKK26392.1 - 0.18 12.0 2.6 0.28 11.4 2.6 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Macoilin PF09726.9 KKK26392.1 - 0.74 8.3 9.2 0.82 8.1 9.2 1.1 1 0 0 1 1 1 0 Macoilin family RNA_pol_Rpc4 PF05132.14 KKK26392.1 - 1.1 9.7 5.0 1.8 9.0 5.0 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 Plasmodium_Vir PF05795.11 KKK26392.1 - 3.1 7.1 6.2 4.2 6.7 6.2 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein RAP1 PF07218.11 KKK26392.1 - 3.8 5.7 14.9 4.9 5.3 14.9 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) NPR3 PF03666.13 KKK26392.1 - 4.1 6.1 8.3 21 3.7 7.7 1.9 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF1180 PF06679.12 KKK26392.1 - 4.7 7.6 9.9 7.6 6.9 9.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1180) Period_C PF12114.8 KKK26392.1 - 9.4 5.8 19.3 18 4.8 19.3 1.4 1 0 0 1 1 1 0 Period protein 2/3C-terminal region Complex1_LYR PF05347.15 KKK26393.1 - 6e-07 29.4 0.4 1.1e-06 28.6 0.4 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KKK26393.1 - 0.034 14.9 0.1 0.039 14.7 0.1 1.3 1 0 0 1 1 1 0 Complex1_LYR-like RAC_head PF16717.5 KKK26394.1 - 4.6e-25 88.5 2.3 4.6e-25 88.5 2.3 3.0 2 1 1 3 3 3 1 Ribosome-associated complex head domain DnaJ PF00226.31 KKK26394.1 - 1.7e-17 63.2 0.4 1.7e-17 63.2 0.4 2.3 2 0 0 2 2 2 1 DnaJ domain Rnk_N PF14760.6 KKK26394.1 - 0.29 11.7 4.1 9.7 6.8 0.0 3.2 3 0 0 3 3 3 0 Rnk N-terminus V_ATPase_I PF01496.19 KKK26394.1 - 0.55 8.1 4.6 0.88 7.4 4.6 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Hid1 PF12722.7 KKK26394.1 - 1.4 7.0 5.7 2 6.4 5.7 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Meleagrin PF08189.11 KKK26395.1 - 0.041 13.6 1.4 0.041 13.6 1.4 2.4 2 0 0 2 2 2 0 Meleagrin/Cygnin family AA_permease_2 PF13520.6 KKK26396.1 - 1.2e-49 169.3 46.2 3e-49 168.0 46.2 1.5 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KKK26396.1 - 2.2e-19 69.4 32.9 4.2e-19 68.5 32.9 1.3 1 0 0 1 1 1 1 Amino acid permease adh_short_C2 PF13561.6 KKK26397.1 - 7.4e-57 192.6 0.4 8.4e-57 192.4 0.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KKK26397.1 - 4.1e-42 143.9 0.2 5.1e-42 143.6 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KKK26397.1 - 4.6e-09 36.4 1.1 6.6e-09 35.9 1.1 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 KKK26397.1 - 0.0093 15.9 0.2 0.019 14.9 0.2 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ChuX_HutX PF06228.13 KKK26397.1 - 0.017 14.9 0.2 0.85 9.4 0.0 2.4 1 1 1 2 2 2 0 Haem utilisation ChuX/HutX Epimerase PF01370.21 KKK26397.1 - 0.024 14.1 0.1 0.039 13.4 0.1 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 KKK26397.1 - 0.061 12.6 0.1 0.18 11.1 0.1 1.8 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Aldedh PF00171.22 KKK26398.1 - 6.8e-127 423.8 0.0 7.7e-127 423.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 KKK26398.1 - 0.062 12.3 0.3 0.47 9.4 0.0 2.0 2 0 0 2 2 2 0 Acyl-CoA reductase (LuxC) Sterol_MT_C PF08498.10 KKK26399.1 - 1.3e-30 105.5 0.2 2.2e-30 104.7 0.2 1.4 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.12 KKK26399.1 - 1.2e-21 77.2 0.0 2.1e-21 76.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKK26399.1 - 1.2e-19 70.8 0.0 2.4e-19 69.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KKK26399.1 - 2.3e-18 66.5 0.0 3.4e-18 65.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KKK26399.1 - 8.7e-13 48.2 0.0 1.3e-12 47.7 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 KKK26399.1 - 4.4e-12 45.8 0.0 7.4e-12 45.1 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 KKK26399.1 - 1e-10 41.7 0.0 1.7e-10 41.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KKK26399.1 - 4.9e-10 40.0 0.0 1e-09 39.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KKK26399.1 - 2.4e-05 24.2 0.0 4e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.13 KKK26399.1 - 0.00022 20.7 0.0 0.00043 19.8 0.0 1.4 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_29 PF03141.16 KKK26399.1 - 0.00031 19.4 0.0 0.00042 19.0 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase RrnaAD PF00398.20 KKK26399.1 - 0.0018 17.4 0.0 0.0027 16.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_15 PF09445.10 KKK26399.1 - 0.0024 17.4 0.0 0.0037 16.9 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase MTS PF05175.14 KKK26399.1 - 0.0036 16.9 0.0 0.0071 15.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain MetW PF07021.12 KKK26399.1 - 0.0049 16.5 0.0 0.0081 15.8 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_2 PF00891.18 KKK26399.1 - 0.0073 15.6 0.0 0.013 14.8 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase domain Sfi1 PF08457.10 KKK26399.1 - 0.018 13.6 0.7 0.018 13.6 0.7 1.3 2 0 0 2 2 2 0 Sfi1 spindle body protein Methyltransf_24 PF13578.6 KKK26399.1 - 0.033 15.2 0.1 0.13 13.3 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain TehB PF03848.14 KKK26399.1 - 0.035 13.5 0.0 0.06 12.7 0.0 1.4 1 0 0 1 1 1 0 Tellurite resistance protein TehB UPF0020 PF01170.18 KKK26399.1 - 0.041 13.6 0.1 0.09 12.4 0.0 1.6 2 0 0 2 2 2 0 Putative RNA methylase family UPF0020 Methyltransf_32 PF13679.6 KKK26399.1 - 0.11 12.5 0.1 0.35 10.9 0.0 1.8 1 1 1 2 2 2 0 Methyltransferase domain TSC21 PF15217.6 KKK26399.1 - 0.14 12.1 0.1 0.22 11.5 0.1 1.3 1 0 0 1 1 1 0 TSC21 family FtsJ PF01728.19 KKK26399.1 - 0.15 12.2 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase Fungal_trans_2 PF11951.8 KKK26400.1 - 7.3e-35 120.5 1.4 1.3e-34 119.7 1.4 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK26400.1 - 1e-06 28.8 11.5 1.8e-06 27.9 11.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_S28 PF05577.12 KKK26401.1 - 1.7e-55 188.6 0.1 4.4e-55 187.2 0.1 1.5 1 1 0 1 1 1 1 Serine carboxypeptidase S28 Gln-synt_C PF00120.24 KKK26402.1 - 5.4e-81 272.3 0.0 1.1e-80 271.3 0.0 1.5 2 0 0 2 2 2 1 Glutamine synthetase, catalytic domain Gln-synt_N_2 PF16952.5 KKK26402.1 - 0.029 14.2 0.0 0.064 13.1 0.0 1.6 1 1 0 1 1 1 0 Glutamine synthetase N-terminal domain MFS_1 PF07690.16 KKK26403.1 - 4.4e-34 117.9 33.9 4.4e-34 117.9 33.9 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Med27 PF11571.8 KKK26404.1 - 2.2e-23 82.4 0.2 4.7e-23 81.3 0.2 1.6 1 0 0 1 1 1 1 Mediator complex subunit 27 DUF812 PF05667.11 KKK26404.1 - 0.0064 15.4 0.2 0.0064 15.4 0.2 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF812) RRM_1 PF00076.22 KKK26406.1 - 2.1e-09 37.0 0.0 3.6e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KKK26406.1 - 0.0058 16.6 0.0 0.01 15.9 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 KKK26406.1 - 0.011 15.7 0.0 0.025 14.6 0.0 1.5 1 0 0 1 1 1 0 RNA binding motif Phosphoesterase PF04185.14 KKK26407.1 - 2.4e-32 112.5 4.1 7.9e-32 110.8 4.1 1.7 1 1 0 1 1 1 1 Phosphoesterase family DUF3533 PF12051.8 KKK26408.1 - 2.8e-130 434.6 8.4 2.8e-130 434.6 8.4 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3533) Sugar_tr PF00083.24 KKK26408.1 - 1.5e-43 149.3 17.6 1.5e-43 149.3 17.6 1.9 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.16 KKK26408.1 - 1.3e-16 60.5 31.4 1.3e-16 60.5 31.4 4.3 3 2 1 4 4 4 2 Major Facilitator Superfamily Bac_rhamnosid6H PF17389.2 KKK26410.1 - 4.9e-124 414.0 0.2 6.1e-124 413.7 0.2 1.1 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid_N PF08531.10 KKK26410.1 - 2.3e-63 213.1 0.0 4.6e-63 212.1 0.0 1.5 1 0 0 1 1 1 1 Alpha-L-rhamnosidase N-terminal domain Bac_rhamnosid PF05592.11 KKK26410.1 - 1.9e-32 111.2 0.0 3.8e-32 110.3 0.0 1.4 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase concanavalin-like domain Bac_rhamnosid_C PF17390.2 KKK26410.1 - 2.6e-15 55.9 0.1 9.9e-15 54.1 0.1 2.0 1 1 0 1 1 1 1 Bacterial alpha-L-rhamnosidase C-terminal domain GDC-P PF02347.16 KKK26411.1 - 5.8e-176 585.5 0.1 2e-163 544.2 0.0 2.5 2 1 0 2 2 2 2 Glycine cleavage system P-protein Amidohydro_1 PF01979.20 KKK26411.1 - 2.4e-64 217.9 0.0 4.4e-64 217.0 0.0 1.5 1 0 0 1 1 1 1 Amidohydrolase family Beta_elim_lyase PF01212.21 KKK26411.1 - 1.5e-05 24.4 0.2 3.6e-05 23.2 0.2 1.5 1 0 0 1 1 1 1 Beta-eliminating lyase Amidohydro_3 PF07969.11 KKK26411.1 - 4.4e-05 23.1 1.4 0.0036 16.8 0.0 2.9 3 0 0 3 3 3 2 Amidohydrolase family DegT_DnrJ_EryC1 PF01041.17 KKK26411.1 - 0.021 14.1 0.9 0.076 12.3 0.0 2.0 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family SPOR PF05036.13 KKK26411.1 - 0.043 14.2 0.0 0.16 12.4 0.0 2.0 1 0 0 1 1 1 0 Sporulation related domain CWC25 PF12542.8 KKK26412.1 - 1.7e-22 80.2 0.0 1.7e-22 80.2 0.0 3.8 3 1 0 3 3 3 1 Pre-mRNA splicing factor Cir_N PF10197.9 KKK26412.1 - 2.9e-14 53.0 9.8 2.9e-14 53.0 9.8 4.5 3 1 1 4 4 4 2 N-terminal domain of CBF1 interacting co-repressor CIR Adaptin_N PF01602.20 KKK26413.1 - 4.6e-116 388.4 10.4 5.9e-116 388.1 10.4 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KKK26413.1 - 8.6e-58 194.9 9.6 7.2e-57 191.9 0.4 3.5 3 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KKK26413.1 - 3.9e-13 49.6 5.2 0.0002 21.7 0.0 5.4 4 2 0 4 4 4 3 HEAT repeats HEAT PF02985.22 KKK26413.1 - 6.8e-09 35.2 3.5 0.034 14.4 0.0 5.9 7 0 0 7 7 7 3 HEAT repeat Atx10homo_assoc PF09759.9 KKK26413.1 - 0.00022 21.2 0.1 8.7 6.4 0.0 4.0 3 1 0 3 3 3 2 Spinocerebellar ataxia type 10 protein domain Arm PF00514.23 KKK26413.1 - 0.0026 17.7 4.0 0.88 9.7 0.0 4.5 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 KKK26413.1 - 0.0053 17.2 5.9 13 6.4 0.0 6.3 6 1 1 7 7 7 1 HEAT-like repeat TIP120 PF08623.10 KKK26413.1 - 0.022 14.6 1.6 2.6 7.8 0.1 3.0 3 0 0 3 3 3 0 TATA-binding protein interacting (TIP20) CLASP_N PF12348.8 KKK26413.1 - 0.035 13.7 2.5 1 8.9 0.0 3.1 4 0 0 4 4 4 0 CLASP N terminal DUF1077 PF06417.12 KKK26414.1 - 3.2e-49 165.8 3.8 4e-49 165.5 3.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) Fungal_trans PF04082.18 KKK26415.1 - 0.0026 16.8 0.3 0.0046 16.0 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Paf67 PF10255.9 KKK26416.1 - 2e-159 531.0 0.0 2.3e-159 530.7 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_2 PF07719.17 KKK26416.1 - 0.087 13.0 0.0 0.6 10.4 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat AAR2 PF05282.11 KKK26417.1 - 4.5e-99 332.2 0.0 5.6e-99 331.9 0.0 1.1 1 0 0 1 1 1 1 AAR2 protein VHP PF02209.19 KKK26417.1 - 0.12 12.5 0.2 6.2 7.0 0.0 2.4 2 0 0 2 2 2 0 Villin headpiece domain Kelch_6 PF13964.6 KKK26417.1 - 0.13 12.6 0.0 0.29 11.5 0.0 1.6 1 0 0 1 1 1 0 Kelch motif Aminotran_4 PF01063.19 KKK26418.1 - 3.8e-28 98.9 0.0 6.8e-28 98.1 0.0 1.4 1 0 0 1 1 1 1 Amino-transferase class IV Ribosomal_S11 PF00411.19 KKK26419.1 - 1.3e-16 61.0 1.8 1.5e-16 60.8 1.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S11 Fe-S_biosyn PF01521.20 KKK26420.1 - 3.2e-11 43.4 0.0 8.9e-11 42.0 0.0 1.7 1 1 0 1 1 1 1 Iron-sulphur cluster biosynthesis Aminotran_5 PF00266.19 KKK26421.1 - 1.6e-07 30.6 0.0 7.2e-07 28.5 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 KKK26421.1 - 0.012 15.0 0.0 0.018 14.3 0.0 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 KKK26421.1 - 0.035 12.6 0.0 0.13 10.7 0.0 1.7 1 1 1 2 2 2 0 Cys/Met metabolism PLP-dependent enzyme Pox_Ag35 PF03286.14 KKK26421.1 - 0.045 13.5 0.3 0.072 12.9 0.3 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein LPMO_10 PF03067.15 KKK26422.1 - 0.0011 19.7 0.0 0.0026 18.5 0.0 1.6 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Glyco_hydro_61 PF03443.14 KKK26422.1 - 0.0012 18.9 0.0 0.0025 17.8 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 NUDE_C PF04880.13 KKK26422.1 - 4.6 7.7 7.9 7.3 7.0 7.9 1.4 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region UPF0029 PF01205.19 KKK26423.1 - 1.5e-32 112.0 0.0 3e-32 111.1 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.22 KKK26423.1 - 1.6e-10 41.3 0.0 2.4e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 RWD domain Casein_kappa PF00997.18 KKK26423.1 - 6.2 6.9 11.6 12 5.9 11.6 1.4 1 0 0 1 1 1 0 Kappa casein DnaJ PF00226.31 KKK26424.1 - 3.9e-16 58.9 0.1 6e-16 58.3 0.1 1.3 1 0 0 1 1 1 1 DnaJ domain Asparaginase PF00710.20 KKK26425.1 - 3.9e-59 199.4 0.0 5.6e-59 198.9 0.0 1.2 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 KKK26425.1 - 2e-26 92.4 0.1 3.8e-26 91.5 0.1 1.5 1 0 0 1 1 1 1 Glutaminase/Asparaginase C-terminal domain Ank_2 PF12796.7 KKK26425.1 - 1e-11 45.2 0.1 4.8e-11 43.1 0.1 2.1 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KKK26425.1 - 7.5e-09 35.1 1.7 0.0082 16.6 0.0 4.3 5 0 0 5 5 5 2 Ankyrin repeat Ank_4 PF13637.6 KKK26425.1 - 2.7e-08 34.2 1.6 0.00026 21.5 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KKK26425.1 - 1.5e-07 31.5 1.1 0.0066 16.9 0.1 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 KKK26425.1 - 6.2e-07 29.6 0.6 3.7e-06 27.1 0.3 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) MTTB PF06253.11 KKK26425.1 - 0.063 11.2 0.1 0.099 10.6 0.1 1.2 1 0 0 1 1 1 0 Trimethylamine methyltransferase (MTTB) Fungal_trans PF04082.18 KKK26426.1 - 1.8e-13 50.1 0.9 2.9e-13 49.5 0.9 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK26426.1 - 3.3e-07 30.3 11.5 7.6e-07 29.2 11.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_L4 PF00573.22 KKK26427.1 - 2.2e-38 131.9 0.5 3e-38 131.5 0.5 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 KKK26427.1 - 5.5e-31 106.4 1.0 1.3e-30 105.3 1.0 1.7 1 0 0 1 1 1 1 60S ribosomal protein L4 C-terminal domain Tetraspanin PF00335.20 KKK26428.1 - 0.082 12.6 3.9 2.5 7.7 0.2 2.7 3 0 0 3 3 3 0 Tetraspanin family Aminotran_1_2 PF00155.21 KKK26429.1 - 1.1e-09 37.9 0.0 2.7e-09 36.7 0.0 1.7 1 1 0 1 1 1 1 Aminotransferase class I and II FokI_N PF02981.15 KKK26429.1 - 0.032 14.4 0.0 0.068 13.3 0.0 1.5 1 0 0 1 1 1 0 Restriction endonuclease FokI, recognition domain HepII_C PF18675.1 KKK26429.1 - 0.15 12.1 0.0 0.8 9.8 0.0 2.2 1 1 0 1 1 1 0 Heparinase II C-terminal domain LCCL PF03815.19 KKK26430.1 - 9.5e-24 83.3 0.1 1.5e-23 82.7 0.1 1.3 1 0 0 1 1 1 1 LCCL domain Longin_2 PF18639.1 KKK26430.1 - 0.16 11.8 0.0 0.25 11.2 0.0 1.2 1 0 0 1 1 1 0 Yeast longin domain Phosphoesterase PF04185.14 KKK26431.1 - 5.9e-66 223.1 2.4 9.2e-66 222.4 2.4 1.3 1 1 0 1 1 1 1 Phosphoesterase family DUF1996 PF09362.10 KKK26432.1 - 3.8e-80 269.3 0.1 3.8e-80 269.3 0.1 2.4 2 1 0 2 2 2 1 Domain of unknown function (DUF1996) SOG2 PF10428.9 KKK26432.1 - 0.23 10.6 20.4 0.32 10.1 20.4 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Apt1 PF10351.9 KKK26432.1 - 0.34 9.7 3.1 0.41 9.5 3.1 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain CPSF100_C PF13299.6 KKK26432.1 - 0.62 10.2 3.9 1 9.5 3.9 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal RIFIN PF02009.16 KKK26432.1 - 7.5 6.4 10.9 11 5.8 10.9 1.2 1 0 0 1 1 1 0 Rifin 2OG-FeII_Oxy_2 PF13532.6 KKK26433.1 - 0.00017 21.8 0.0 0.00021 21.5 0.0 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily CENP-B_dimeris PF09026.10 KKK26433.1 - 2.2 8.7 9.3 3.7 8.0 9.3 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain TAP42 PF04177.12 KKK26433.1 - 4.2 6.4 7.6 6 5.9 7.6 1.2 1 0 0 1 1 1 0 TAP42-like family NOA36 PF06524.12 KKK26433.1 - 6.3 6.0 6.8 8.1 5.7 6.8 1.1 1 0 0 1 1 1 0 NOA36 protein Steroid_dh PF02544.16 KKK26434.1 - 4.2e-13 49.5 0.5 1.1e-12 48.2 0.3 1.8 1 1 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase Vac_ImportDeg PF09783.9 KKK26435.1 - 1.8e-41 141.6 0.2 5.3e-41 140.1 0.2 1.7 2 0 0 2 2 2 1 Vacuolar import and degradation protein Ribosomal_L7Ae PF01248.26 KKK26436.1 - 2.2e-24 85.0 0.6 5e-24 83.9 0.6 1.6 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Ank_2 PF12796.7 KKK26436.1 - 1.7e-20 73.4 0.2 4.6e-12 46.4 0.1 2.9 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KKK26436.1 - 1.7e-16 60.4 0.0 0.00043 20.8 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KKK26436.1 - 4.4e-16 58.7 0.3 5.5e-07 29.8 0.1 4.4 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 KKK26436.1 - 1.1e-13 50.9 0.1 0.0012 19.2 0.0 4.7 4 0 0 4 4 4 4 Ankyrin repeat Ank_3 PF13606.6 KKK26436.1 - 3.4e-10 39.3 0.1 0.056 14.0 0.0 4.5 5 0 0 5 5 5 3 Ankyrin repeat IU_nuc_hydro PF01156.19 KKK26437.1 - 5e-82 275.9 0.0 5.9e-82 275.7 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase HTH_Tnp_Tc5 PF03221.16 KKK26438.1 - 4.5e-18 65.0 0.0 8.3e-18 64.2 0.0 1.4 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain CDO_I PF05995.12 KKK26439.1 - 8.8e-38 129.3 0.5 1.8e-30 105.5 0.0 2.1 1 1 1 2 2 2 2 Cysteine dioxygenase type I PCO_ADO PF07847.12 KKK26439.1 - 0.00075 19.0 0.0 0.0011 18.5 0.0 1.3 1 0 0 1 1 1 1 PCO_ADO MMR_HSR1_Xtn PF16897.5 KKK26440.1 - 6.4e-40 135.4 0.7 2.4e-39 133.6 0.2 2.1 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 KKK26440.1 - 4.4e-21 75.1 0.1 1.1e-20 73.8 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase TGS PF02824.21 KKK26440.1 - 5.9e-19 67.9 0.0 1.5e-18 66.6 0.0 1.7 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.18 KKK26440.1 - 6.1e-10 38.8 0.1 3.3e-09 36.5 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 KKK26440.1 - 0.00046 19.8 0.1 4.4 6.8 0.0 3.9 2 2 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 KKK26440.1 - 0.00097 19.2 0.3 0.22 11.5 0.0 2.4 1 1 1 2 2 2 2 Dynamin family MeaB PF03308.16 KKK26440.1 - 0.0085 15.1 0.1 0.018 14.0 0.1 1.5 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Arf PF00025.21 KKK26440.1 - 0.034 13.6 0.2 2.3 7.6 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family RsgA_GTPase PF03193.16 KKK26440.1 - 0.048 13.6 1.0 2.5 8.0 0.1 3.0 2 1 1 3 3 3 0 RsgA GTPase Abhydrolase_6 PF12697.7 KKK26441.1 - 4.8e-16 60.0 0.0 8.7e-15 55.9 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KKK26441.1 - 1.8e-15 57.3 0.0 1.7e-14 54.1 0.1 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KKK26441.1 - 6.5e-07 28.9 0.0 1.9e-06 27.4 0.0 1.8 3 0 0 3 3 3 1 Serine aminopeptidase, S33 EHN PF06441.12 KKK26441.1 - 0.023 15.0 0.2 0.055 13.8 0.2 1.6 1 0 0 1 1 1 0 Epoxide hydrolase N terminus LIDHydrolase PF10230.9 KKK26441.1 - 0.028 14.0 0.0 0.054 13.0 0.0 1.4 1 1 0 1 1 1 0 Lipid-droplet associated hydrolase Abhydrolase_2 PF02230.16 KKK26441.1 - 0.052 13.3 0.0 11 5.7 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase MR_MLE_C PF13378.6 KKK26442.1 - 1.2e-56 191.7 0.0 1.7e-56 191.3 0.0 1.1 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 KKK26442.1 - 1.8e-14 54.0 0.0 1.4e-13 51.1 0.0 2.2 1 1 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain PXA PF02194.15 KKK26443.1 - 1e-47 162.5 0.6 3.3e-47 160.8 0.1 2.0 2 0 0 2 2 2 1 PXA domain Glyco_transf_8 PF01501.20 KKK26444.1 - 2.4e-22 79.7 0.1 2e-21 76.7 0.1 2.1 1 1 0 1 1 1 1 Glycosyl transferase family 8 Adenylsucc_synt PF00709.21 KKK26444.1 - 0.16 10.8 0.1 0.23 10.3 0.1 1.1 1 0 0 1 1 1 0 Adenylosuccinate synthetase LacAB_rpiB PF02502.18 KKK26445.1 - 5.4e-40 136.6 0.0 9e-40 135.9 0.0 1.4 1 0 0 1 1 1 1 Ribose/Galactose Isomerase U-box PF04564.15 KKK26445.1 - 1e-20 73.7 0.0 2.5e-20 72.4 0.0 1.7 1 0 0 1 1 1 1 U-box domain TPR_2 PF07719.17 KKK26445.1 - 5.6e-07 29.2 6.4 0.00067 19.6 0.1 5.0 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 KKK26445.1 - 0.00016 21.3 0.2 0.00016 21.3 0.2 4.7 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_11 PF13414.6 KKK26445.1 - 0.00022 20.9 3.0 0.001 18.7 0.0 3.3 3 0 0 3 3 3 1 TPR repeat TPR_14 PF13428.6 KKK26445.1 - 0.00055 20.5 6.4 2.3 9.3 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 KKK26445.1 - 0.00059 20.3 7.0 0.27 11.8 0.5 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KKK26445.1 - 0.001 19.3 0.2 0.019 15.2 0.2 2.4 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 CHIP_TPR_N PF18391.1 KKK26445.1 - 0.0054 17.5 2.3 0.011 16.5 2.3 1.5 1 0 0 1 1 1 1 CHIP N-terminal tetratricopeptide repeat domain TPR_17 PF13431.6 KKK26445.1 - 0.0064 16.8 1.6 3.2 8.3 0.1 3.5 3 1 1 4 4 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 KKK26445.1 - 0.012 15.8 5.7 0.32 11.3 0.5 3.1 3 1 0 3 3 3 0 Tetratricopeptide repeat GvpG PF05120.12 KKK26445.1 - 0.035 14.1 0.4 0.08 13.0 0.4 1.5 1 0 0 1 1 1 0 Gas vesicle protein G Gly_rich_SFCGS PF14272.6 KKK26445.1 - 0.044 13.8 0.0 0.083 12.9 0.0 1.4 1 0 0 1 1 1 0 Glycine-rich SFCGS GlnD_UR_UTase PF08335.11 KKK26445.1 - 0.046 13.8 3.0 0.082 13.0 3.0 1.3 1 0 0 1 1 1 0 GlnD PII-uridylyltransferase TPR_7 PF13176.6 KKK26445.1 - 0.088 12.9 0.6 5.2 7.3 0.0 3.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 KKK26445.1 - 0.88 10.3 12.3 5.1 7.8 3.1 3.7 3 1 1 4 4 4 0 Tetratricopeptide repeat ACBP PF00887.19 KKK26446.1 - 1.3e-16 60.6 1.1 2e-16 60.0 1.1 1.3 1 0 0 1 1 1 1 Acyl CoA binding protein Methyltransf_25 PF13649.6 KKK26447.1 - 2.3e-07 31.4 0.0 3.2e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KKK26447.1 - 5.4e-05 22.6 0.0 6.7e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 KKK26447.1 - 0.00038 20.3 0.0 0.00053 19.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KKK26447.1 - 0.0016 19.0 0.0 0.0023 18.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KKK26447.1 - 0.01 16.6 0.0 0.014 16.1 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain RseA_C PF03873.13 KKK26448.1 - 0.19 12.0 0.1 0.32 11.3 0.1 1.3 1 0 0 1 1 1 0 Anti sigma-E protein RseA, C-terminal domain NOT2_3_5 PF04153.18 KKK26449.1 - 8.6e-27 93.8 0.1 3.1e-26 92.0 0.0 1.9 2 0 0 2 2 2 1 NOT2 / NOT3 / NOT5 family MRP-L47 PF06984.13 KKK26450.1 - 1.3e-19 70.1 0.2 1.8e-19 69.6 0.2 1.2 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Clc-like PF07062.12 KKK26450.1 - 0.45 9.9 2.8 0.76 9.2 2.8 1.3 1 0 0 1 1 1 0 Clc-like Tyr-DNA_phospho PF06087.12 KKK26451.1 - 6.5e-164 545.8 0.0 8.1e-164 545.5 0.0 1.1 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase DIE2_ALG10 PF04922.12 KKK26451.1 - 1.7e-124 416.1 5.8 2.3e-124 415.7 5.8 1.2 1 0 0 1 1 1 1 DIE2/ALG10 family PLDc_2 PF13091.6 KKK26451.1 - 0.15 12.0 0.0 4.8 7.1 0.0 2.3 2 0 0 2 2 2 0 PLD-like domain Sld5 PF05916.11 KKK26452.1 - 1.5e-36 125.2 0.0 3.2e-36 124.1 0.0 1.6 1 1 0 1 1 1 1 GINS complex protein CUE PF02845.16 KKK26453.1 - 8.4e-12 44.6 0.0 1.3e-11 44.0 0.0 1.3 1 0 0 1 1 1 1 CUE domain G2BR PF18442.1 KKK26453.1 - 0.055 13.1 12.8 0.095 12.4 12.8 1.4 1 0 0 1 1 1 0 E3 gp78 Ube2g2-binding region (G2BR) SMC_N PF02463.19 KKK26454.1 - 1.5e-70 237.0 0.2 6.2e-70 235.1 0.2 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KKK26454.1 - 4.7e-22 78.5 3.7 8.9e-22 77.6 0.2 2.9 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.6 KKK26454.1 - 5.1e-13 50.0 5.6 5.1e-13 50.0 5.6 6.4 2 2 3 5 5 5 1 AAA domain AAA_21 PF13304.6 KKK26454.1 - 2.6e-11 43.9 5.3 0.00021 21.2 0.1 4.2 3 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system HIP1_clath_bdg PF16515.5 KKK26454.1 - 5.4e-05 23.7 8.5 5.4e-05 23.7 8.5 9.7 3 2 7 10 10 10 1 Clathrin-binding domain of Huntingtin-interacting protein 1 AAA_29 PF13555.6 KKK26454.1 - 0.00012 21.7 0.1 0.00032 20.4 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain ApbA_C PF08546.11 KKK26454.1 - 0.53 10.5 5.0 2.6 8.2 0.4 3.1 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA C terminal zf-RING_2 PF13639.6 KKK26455.1 - 2.2e-12 47.1 5.2 3.4e-12 46.5 5.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 KKK26455.1 - 5.5e-09 36.2 3.0 1.1e-08 35.2 3.0 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 KKK26455.1 - 5.3e-08 32.6 4.4 8.8e-08 31.9 4.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KKK26455.1 - 5.9e-08 32.5 4.4 9e-08 31.9 4.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KKK26455.1 - 2.6e-07 30.2 1.5 4.8e-07 29.4 1.5 1.4 1 0 0 1 1 1 1 RING-like zinc finger Zn_ribbon_17 PF17120.5 KKK26455.1 - 2e-05 24.1 1.5 3.2e-05 23.5 1.5 1.2 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 KKK26455.1 - 9.1e-05 22.3 3.0 0.00014 21.8 3.0 1.3 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KKK26455.1 - 0.00018 21.3 2.2 0.00032 20.5 2.2 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 KKK26455.1 - 0.00053 20.0 2.1 0.0012 18.9 2.1 1.6 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 KKK26455.1 - 0.00069 19.6 4.2 0.0013 18.7 4.2 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KKK26455.1 - 0.0015 18.3 3.1 0.0024 17.7 3.1 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.7 KKK26455.1 - 0.0027 17.8 5.5 0.0041 17.2 5.5 1.3 1 0 0 1 1 1 1 RING-variant domain zf-C3H2C3 PF17122.5 KKK26455.1 - 0.0045 17.0 1.7 0.0089 16.0 1.7 1.4 1 0 0 1 1 1 1 Zinc-finger zf-Nse PF11789.8 KKK26455.1 - 0.023 14.5 2.0 0.049 13.5 1.4 1.8 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_5 PF17121.5 KKK26455.1 - 0.11 12.4 1.3 0.2 11.6 1.3 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 KKK26455.1 - 0.27 11.1 3.7 0.43 10.4 3.7 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.8 KKK26455.1 - 0.32 11.2 3.3 0.6 10.3 3.3 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain zf-RING-like PF08746.11 KKK26455.1 - 0.43 10.9 2.6 0.75 10.1 2.6 1.3 1 0 0 1 1 1 0 RING-like domain PHD PF00628.29 KKK26455.1 - 0.58 10.1 3.9 0.96 9.4 3.9 1.4 1 0 0 1 1 1 0 PHD-finger ECM11 PF15463.6 KKK26456.1 - 9.5e-37 126.5 2.0 9.5e-37 126.5 2.0 3.0 3 0 0 3 3 3 1 Extracellular mutant protein 11 RNA_pol_I_TF PF04090.12 KKK26456.1 - 7.2e-12 45.2 0.0 1e-10 41.4 0.0 2.2 1 1 0 1 1 1 1 RNA polymerase I specific initiation factor Rieske PF00355.26 KKK26457.1 - 1.1e-08 34.9 0.0 2.1e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 KKK26457.1 - 0.00013 21.8 0.0 0.00026 20.9 0.0 1.4 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Pkinase PF00069.25 KKK26458.1 - 2.2e-11 43.6 0.0 3.9e-09 36.3 0.0 2.7 2 1 0 2 2 2 1 Protein kinase domain Kinase-like PF14531.6 KKK26458.1 - 0.00032 20.1 0.2 0.22 10.8 0.1 2.7 3 0 0 3 3 3 2 Kinase-like Pkinase_Tyr PF07714.17 KKK26458.1 - 0.0012 18.2 0.1 0.088 12.1 0.2 2.8 2 1 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 KKK26458.1 - 0.0089 16.0 0.0 0.016 15.2 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KKK26458.1 - 0.2 11.0 0.0 0.36 10.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family VPS9 PF02204.18 KKK26459.1 - 3.7e-26 91.4 0.0 9e-26 90.1 0.0 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF5601 PF18151.1 KKK26459.1 - 0.17 12.2 0.1 0.7 10.3 0.1 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF5601) Lipase_3 PF01764.25 KKK26460.1 - 2.9e-06 27.2 0.0 7.4e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.13 KKK26460.1 - 0.055 13.2 0.0 0.086 12.5 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Hydrolase_4 PF12146.8 KKK26460.1 - 0.1 11.8 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Catalase PF00199.19 KKK26461.1 - 2.7e-193 642.3 0.4 3.4e-193 642.0 0.4 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 KKK26461.1 - 5.4e-11 42.5 0.0 1.6e-10 41.0 0.0 1.9 1 0 0 1 1 1 1 Catalase-related immune-responsive Fungal_trans_2 PF11951.8 KKK26461.1 - 1.7e-05 23.9 0.4 2.7e-05 23.2 0.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Sugar_tr PF00083.24 KKK26462.1 - 2e-87 294.0 21.2 2.4e-87 293.7 21.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKK26462.1 - 8.3e-15 54.6 35.7 1.1e-10 41.0 27.8 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KKK26462.1 - 0.00089 18.2 3.9 0.00089 18.2 3.9 2.3 2 0 0 2 2 2 2 MFS_1 like family LtrA PF06772.11 KKK26463.1 - 2.5e-37 129.0 22.6 3.1e-37 128.6 22.6 1.1 1 0 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) MFS_MOT1 PF16983.5 KKK26463.1 - 7.8 7.0 8.3 1.4 9.4 3.6 2.3 2 1 0 2 2 2 0 Molybdate transporter of MFS superfamily adh_short_C2 PF13561.6 KKK26464.1 - 1e-38 133.2 0.5 8.4e-37 127.0 0.5 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KKK26464.1 - 4.2e-27 94.9 0.6 1.7e-25 89.7 0.6 2.0 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KKK26464.1 - 0.0011 18.9 0.2 0.014 15.3 0.1 2.1 1 1 1 2 2 2 1 KR domain ORC4_C PF14629.6 KKK26465.1 - 1.8e-51 174.6 0.0 2.7e-51 174.0 0.0 1.3 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.6 KKK26465.1 - 1.7e-13 51.3 0.1 5.9e-13 49.5 0.1 2.0 1 0 0 1 1 1 1 AAA ATPase domain DUF815 PF05673.13 KKK26465.1 - 2.5e-06 26.8 0.1 4.8e-06 25.9 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 KKK26465.1 - 1.2e-05 25.7 0.0 3.2e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 KKK26465.1 - 4e-05 24.0 0.0 0.00014 22.3 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) KAP_NTPase PF07693.14 KKK26465.1 - 0.0003 20.2 0.0 0.00061 19.1 0.0 1.4 2 0 0 2 2 2 1 KAP family P-loop domain NACHT PF05729.12 KKK26465.1 - 0.0017 18.3 1.7 0.0081 16.1 0.6 2.7 2 1 0 2 2 2 1 NACHT domain AAA_29 PF13555.6 KKK26465.1 - 0.0076 16.0 0.1 0.02 14.6 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain ATPase_2 PF01637.18 KKK26465.1 - 0.015 15.2 0.0 0.043 13.7 0.0 1.7 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_19 PF13245.6 KKK26465.1 - 0.021 15.2 0.1 0.045 14.1 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KKK26465.1 - 0.042 13.3 0.1 0.089 12.3 0.1 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region ThiS-like PF14453.6 KKK26465.1 - 0.064 13.3 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 ThiS-like ubiquitin ABC_tran PF00005.27 KKK26465.1 - 0.11 13.0 0.0 0.54 10.8 0.0 2.1 2 0 0 2 2 2 0 ABC transporter NB-ARC PF00931.22 KKK26465.1 - 0.18 11.0 0.1 0.32 10.1 0.1 1.3 1 0 0 1 1 1 0 NB-ARC domain PIF1 PF05970.14 KKK26465.1 - 0.2 10.8 0.1 0.34 10.0 0.1 1.3 1 0 0 1 1 1 0 PIF1-like helicase ORC6 PF05460.13 KKK26465.1 - 1.5 8.0 10.8 3.1 7.0 10.8 1.5 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Zn_clus PF00172.18 KKK26466.1 - 1.8e-11 44.0 10.9 3.3e-11 43.1 10.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KKK26466.1 - 3.9e-10 39.1 0.2 6.2e-10 38.4 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Rer1 PF03248.13 KKK26467.1 - 3.6e-80 267.7 6.1 4.1e-80 267.5 6.1 1.0 1 0 0 1 1 1 1 Rer1 family ECH_1 PF00378.20 KKK26468.1 - 2.6e-78 262.8 0.1 3.1e-78 262.6 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KKK26468.1 - 3.2e-36 125.5 0.4 3.8e-33 115.4 0.1 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase TIM PF00121.18 KKK26469.1 - 7.7e-39 133.5 0.0 9.5e-39 133.2 0.0 1.1 1 0 0 1 1 1 1 Triosephosphate isomerase DHO_dh PF01180.21 KKK26470.1 - 4.1e-63 213.4 0.1 1.4e-53 182.0 0.0 2.1 2 0 0 2 2 2 2 Dihydroorotate dehydrogenase NMO PF03060.15 KKK26470.1 - 0.017 14.5 0.1 0.027 13.8 0.1 1.2 1 0 0 1 1 1 0 Nitronate monooxygenase PcrB PF01884.17 KKK26470.1 - 0.031 13.7 0.5 5.9 6.3 0.1 2.3 2 0 0 2 2 2 0 PcrB family FMN_dh PF01070.18 KKK26470.1 - 0.082 11.9 0.3 2 7.4 0.5 2.6 2 1 0 2 2 2 0 FMN-dependent dehydrogenase PLA2_B PF01735.18 KKK26471.1 - 5.4e-194 645.2 1.3 6.5e-194 644.9 1.3 1.1 1 0 0 1 1 1 1 Lysophospholipase catalytic domain Paf1 PF03985.13 KKK26473.1 - 1.1e-55 189.4 0.0 1.1e-55 189.4 0.0 1.7 2 0 0 2 2 2 1 Paf1 Actin PF00022.19 KKK26473.1 - 1.2e-28 99.9 0.0 1.6e-17 63.2 0.0 2.4 2 0 0 2 2 2 2 Actin MreB_Mbl PF06723.13 KKK26473.1 - 0.00014 20.8 0.1 0.16 10.8 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein Actin_micro PF17003.5 KKK26473.1 - 0.0002 20.7 0.2 0.006 15.8 0.1 2.6 3 0 0 3 3 3 1 Putative actin-like family FtsA PF14450.6 KKK26473.1 - 0.013 15.9 0.0 0.038 14.4 0.0 1.9 2 0 0 2 2 2 0 Cell division protein FtsA TAT_ubiq PF07706.12 KKK26473.1 - 0.18 12.0 0.3 36 4.7 0.0 3.3 3 0 0 3 3 3 0 Aminotransferase ubiquitination site DUF2114 PF09887.9 KKK26473.1 - 0.19 10.2 0.1 0.26 9.7 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2114) Arf PF00025.21 KKK26474.1 - 9.9e-74 246.5 0.0 1.2e-73 246.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KKK26474.1 - 5.9e-14 52.3 0.0 7.9e-14 51.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 KKK26474.1 - 2.4e-12 46.6 0.0 4.2e-12 45.9 0.0 1.2 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 KKK26474.1 - 3e-10 39.8 0.2 4.5e-06 26.1 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 KKK26474.1 - 5.1e-10 39.2 0.0 6e-10 39.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 KKK26474.1 - 1.2e-08 34.6 0.0 1.6e-08 34.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KKK26474.1 - 2.7e-06 27.4 0.0 4.7e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KKK26474.1 - 0.00064 19.3 0.0 0.051 13.1 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 KKK26474.1 - 0.02 14.4 0.4 0.065 12.8 0.4 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_18 PF13238.6 KKK26474.1 - 0.087 13.4 0.1 0.18 12.3 0.0 1.5 1 1 0 1 1 1 0 AAA domain ADH_zinc_N PF00107.26 KKK26475.1 - 2.4e-25 89.0 0.2 3.8e-25 88.4 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KKK26475.1 - 9.9e-10 39.6 0.0 1.5e-09 39.0 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KKK26475.1 - 1.8e-08 34.2 0.4 3.5e-08 33.3 0.4 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.25 KKK26475.1 - 0.057 12.9 0.6 0.16 11.4 0.4 1.9 1 1 0 1 1 1 0 short chain dehydrogenase DUF3419 PF11899.8 KKK26476.1 - 7.5e-159 529.0 0.0 9.7e-159 528.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_23 PF13489.6 KKK26476.1 - 6.6e-13 48.8 0.0 2e-11 44.0 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KKK26476.1 - 1.1e-08 35.6 0.0 4.5e-08 33.7 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKK26476.1 - 5.5e-08 33.4 0.0 8.1e-07 29.7 0.0 2.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KKK26476.1 - 3.2e-06 27.0 0.0 1.6e-05 24.7 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KKK26476.1 - 4.3e-06 27.3 0.0 0.00014 22.5 0.0 3.1 2 1 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 KKK26476.1 - 9.7e-06 25.1 0.0 4.2e-05 23.0 0.0 1.9 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family PCMT PF01135.19 KKK26476.1 - 0.00019 21.3 0.0 0.00036 20.3 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_2 PF00891.18 KKK26476.1 - 0.029 13.7 0.0 0.062 12.6 0.0 1.5 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_32 PF13679.6 KKK26476.1 - 0.08 12.9 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DEAD PF00270.29 KKK26477.1 - 9.7e-27 93.8 0.0 1.8e-26 93.0 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF1998 PF09369.10 KKK26477.1 - 5.5e-18 65.5 0.8 2.1e-17 63.6 0.8 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF1998) Helicase_C PF00271.31 KKK26477.1 - 3e-12 46.9 0.1 1.4e-11 44.7 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KKK26477.1 - 4.8e-05 23.4 0.0 9.8e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Formyl_trans_N PF00551.19 KKK26478.1 - 8.3e-37 126.7 0.0 9.7e-37 126.4 0.0 1.1 1 0 0 1 1 1 1 Formyl transferase Fungal_trans_2 PF11951.8 KKK26479.1 - 3.4e-13 49.2 0.7 4.8e-13 48.7 0.7 1.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK26479.1 - 1.3e-07 31.6 8.6 2.2e-07 30.8 8.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3987 PF13148.6 KKK26480.1 - 9.6 5.1 8.5 17 4.3 8.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Yip1 PF04893.17 KKK26481.1 - 3.4e-14 52.9 13.3 5.5e-14 52.3 13.3 1.4 1 0 0 1 1 1 1 Yip1 domain DUF1282 PF06930.12 KKK26481.1 - 0.07 12.9 5.5 0.11 12.3 5.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1282) 4HBT PF03061.22 KKK26482.1 - 3.8e-11 43.2 0.2 5.3e-11 42.7 0.2 1.2 1 0 0 1 1 1 1 Thioesterase superfamily GDI PF00996.18 KKK26483.1 - 2.3e-196 652.5 0.0 2.5e-196 652.4 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor Pyr_redox PF00070.27 KKK26483.1 - 0.0057 17.2 0.2 0.3 11.7 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KKK26483.1 - 0.031 14.5 0.0 0.075 13.3 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Ran_BP1 PF00638.18 KKK26484.1 - 2.9e-19 69.5 0.1 5.3e-19 68.7 0.1 1.3 1 0 0 1 1 1 1 RanBP1 domain PPR_2 PF13041.6 KKK26485.1 - 3.1e-25 88.1 1.6 9.2e-18 64.2 0.7 3.2 3 0 0 3 3 3 2 PPR repeat family PPR_3 PF13812.6 KKK26485.1 - 3.5e-11 43.0 0.1 5.5e-06 26.4 0.1 3.1 3 0 0 3 3 3 2 Pentatricopeptide repeat domain PPR PF01535.20 KKK26485.1 - 9.7e-07 28.6 4.5 0.087 13.1 0.2 4.3 5 0 0 5 5 5 3 PPR repeat PPR_long PF17177.4 KKK26485.1 - 8.2e-06 25.3 0.0 1.8e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 KKK26485.1 - 5.8e-05 22.7 0.1 0.1 12.3 0.0 3.7 3 0 0 3 3 3 2 PPR repeat zf-C2H2 PF00096.26 KKK26486.1 - 5.9e-06 26.5 11.9 0.0029 18.0 1.8 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KKK26486.1 - 0.00027 21.2 3.8 0.00027 21.2 3.8 3.2 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KKK26486.1 - 0.0004 21.0 11.3 0.071 14.0 2.9 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger TylF PF05711.11 KKK26486.1 - 0.26 10.6 0.0 0.39 9.9 0.0 1.2 1 0 0 1 1 1 0 Macrocin-O-methyltransferase (TylF) zf-H2C2_5 PF13909.6 KKK26486.1 - 1.1 9.1 5.6 2.4 8.0 0.4 2.8 2 0 0 2 2 2 0 C2H2-type zinc-finger domain PNP_phzG_C PF10590.9 KKK26487.1 - 3e-19 68.8 3.9 3e-19 68.8 3.9 2.7 3 0 0 3 3 3 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Putative_PNPOx PF01243.20 KKK26487.1 - 1e-10 41.6 0.0 0.00062 19.9 0.0 2.7 3 0 0 3 3 3 2 Pyridoxamine 5'-phosphate oxidase EamA PF00892.20 KKK26488.1 - 2.8e-06 27.5 11.7 5.4e-05 23.4 11.7 2.0 1 1 0 1 1 1 1 EamA-like transporter family TMEM234 PF10639.9 KKK26488.1 - 0.0025 17.8 0.6 0.0029 17.6 0.6 1.2 1 0 0 1 1 1 1 Putative transmembrane family 234 Rieske PF00355.26 KKK26489.1 - 2.4e-11 43.4 0.0 4.6e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain UCR_TM PF02921.14 KKK26489.1 - 5.5e-11 42.8 0.6 1.4e-10 41.5 0.6 1.7 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region She9_MDM33 PF05546.11 KKK26490.1 - 4.5e-88 294.3 8.7 6.5e-88 293.7 8.7 1.2 1 0 0 1 1 1 1 She9 / Mdm33 family SARAF PF06682.12 KKK26490.1 - 0.0015 18.3 0.7 0.0033 17.1 0.7 1.6 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis Pex14_N PF04695.13 KKK26490.1 - 0.031 14.9 9.0 0.071 13.8 1.7 2.9 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2175 PF09943.9 KKK26490.1 - 0.14 12.4 0.3 0.41 11.0 0.3 1.8 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2175) PsbH PF00737.20 KKK26490.1 - 2 8.2 6.3 0.11 12.3 0.8 1.7 2 0 0 2 2 2 0 Photosystem II 10 kDa phosphoprotein Voltage_CLC PF00654.20 KKK26491.1 - 1.8e-90 303.7 31.2 1.8e-90 303.7 31.2 1.8 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 KKK26491.1 - 2.1e-12 47.3 0.0 2.4e-05 24.7 0.0 2.8 2 0 0 2 2 2 2 CBS domain ATPase_gene1 PF09527.10 KKK26491.1 - 1.1 9.5 10.4 5.3 7.3 2.4 3.2 2 0 0 2 2 2 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter CBFD_NFYB_HMF PF00808.23 KKK26492.1 - 3.8e-14 52.7 0.1 3.8e-14 52.7 0.1 2.0 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KKK26492.1 - 9.3e-05 22.8 0.1 9.3e-05 22.8 0.1 2.1 2 1 0 2 2 2 1 Core histone H2A/H2B/H3/H4 Pol_alpha_B_N PF08418.10 KKK26492.1 - 0.015 15.3 0.7 0.018 15.0 0.7 1.1 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal SH3_9 PF14604.6 KKK26493.1 - 7.9e-05 22.4 0.1 0.00018 21.3 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KKK26493.1 - 0.0023 17.5 0.0 0.0052 16.4 0.0 1.6 1 0 0 1 1 1 1 SH3 domain EphA2_TM PF14575.6 KKK26493.1 - 0.041 14.8 0.0 0.081 13.8 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Adeno_E3_CR2 PF02439.15 KKK26493.1 - 0.18 11.6 0.4 0.39 10.5 0.4 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Cofilin_ADF PF00241.20 KKK26494.1 - 1.6e-32 111.9 0.0 1.8e-32 111.7 0.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein SpoVR PF04293.13 KKK26494.1 - 0.11 11.2 0.0 0.14 10.8 0.0 1.1 1 0 0 1 1 1 0 SpoVR like protein Pmp3 PF01679.17 KKK26495.1 - 4.8e-19 68.3 9.4 6.1e-19 68.0 9.4 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator Peptidase_C14 PF00656.22 KKK26496.1 - 0.00035 20.6 0.0 0.00052 20.1 0.0 1.3 1 0 0 1 1 1 1 Caspase domain Raptor_N PF14538.6 KKK26496.1 - 0.016 15.2 0.0 0.046 13.7 0.0 1.8 2 0 0 2 2 2 0 Raptor N-terminal CASPase like domain ABC_membrane PF00664.23 KKK26497.1 - 4.9e-108 360.9 34.4 4.2e-54 184.1 13.9 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KKK26497.1 - 1.8e-52 177.5 1.1 1.2e-32 113.3 0.0 2.8 3 0 0 3 3 2 2 ABC transporter SMC_N PF02463.19 KKK26497.1 - 8.9e-09 35.1 0.9 5.5e-06 26.0 0.6 3.5 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 KKK26497.1 - 3.4e-07 30.3 0.0 0.032 14.1 0.0 3.4 3 0 0 3 3 3 2 RsgA GTPase AAA_29 PF13555.6 KKK26497.1 - 4.1e-07 29.7 0.5 0.0055 16.4 0.2 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 KKK26497.1 - 3.4e-06 27.6 2.2 0.079 13.3 0.7 3.3 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 KKK26497.1 - 9.5e-06 25.9 0.9 0.079 13.2 0.0 3.3 2 1 0 2 2 2 2 AAA domain AAA PF00004.29 KKK26497.1 - 8.8e-05 22.9 0.1 1.9 8.9 0.0 3.7 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 KKK26497.1 - 0.0003 20.4 0.0 0.27 10.8 0.1 2.5 2 0 0 2 2 2 2 AAA domain Rad17 PF03215.15 KKK26497.1 - 0.00038 20.4 0.1 0.064 13.2 0.0 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_30 PF13604.6 KKK26497.1 - 0.00078 19.2 2.9 0.87 9.3 0.0 3.3 4 0 0 4 4 4 2 AAA domain AAA_5 PF07728.14 KKK26497.1 - 0.0019 18.2 0.0 3.1 7.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 KKK26497.1 - 0.0019 17.9 0.0 0.66 9.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 KKK26497.1 - 0.0021 17.6 0.0 1.3 8.5 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_33 PF13671.6 KKK26497.1 - 0.0024 18.1 0.3 1.8 8.7 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_21 PF13304.6 KKK26497.1 - 0.0035 17.2 0.1 4.1 7.1 0.0 2.9 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_18 PF13238.6 KKK26497.1 - 0.006 17.1 0.0 5.3 7.6 0.0 2.8 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 KKK26497.1 - 0.0082 16.5 0.1 2.2 8.7 0.0 3.2 3 0 0 3 3 2 1 RNA helicase Zeta_toxin PF06414.12 KKK26497.1 - 0.01 15.2 0.2 4.3 6.6 0.0 2.6 3 0 0 3 3 3 1 Zeta toxin AAA_15 PF13175.6 KKK26497.1 - 0.01 15.6 0.0 4.3 6.9 0.0 2.6 2 0 0 2 2 2 0 AAA ATPase domain SRP54 PF00448.22 KKK26497.1 - 0.013 15.1 0.3 0.95 9.1 0.0 2.7 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain DUF87 PF01935.17 KKK26497.1 - 0.023 14.8 0.1 5.1 7.1 0.1 2.6 2 0 0 2 2 2 0 Helicase HerA, central domain PRK PF00485.18 KKK26497.1 - 0.024 14.4 0.0 1.2 8.8 0.0 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Cytidylate_kin PF02224.18 KKK26497.1 - 0.048 13.4 0.0 4.1 7.1 0.0 2.7 2 0 0 2 2 2 0 Cytidylate kinase AAA_23 PF13476.6 KKK26497.1 - 0.049 14.1 4.2 2.5 8.5 0.0 3.4 3 0 0 3 3 2 0 AAA domain ABC_ATPase PF09818.9 KKK26497.1 - 0.051 12.4 1.1 0.077 11.8 0.1 1.7 2 0 0 2 2 2 0 Predicted ATPase of the ABC class G-alpha PF00503.20 KKK26497.1 - 0.053 12.7 0.0 3.3 6.8 0.0 2.4 2 0 0 2 2 2 0 G-protein alpha subunit APS_kinase PF01583.20 KKK26497.1 - 0.073 13.0 0.1 2.7 7.9 0.0 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_17 PF13207.6 KKK26497.1 - 0.11 12.9 1.0 12 6.3 0.0 3.3 3 1 1 4 4 3 0 AAA domain AAA_28 PF13521.6 KKK26497.1 - 0.12 12.6 1.0 4.2 7.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 KKK26497.1 - 1.6 8.8 3.8 13 5.9 0.0 3.3 3 0 0 3 3 3 0 50S ribosome-binding GTPase CDC45 PF02724.14 KKK26497.1 - 9.7 4.3 9.8 0.13 10.6 1.2 1.8 2 0 0 2 2 2 0 CDC45-like protein PPR_2 PF13041.6 KKK26498.1 - 5e-44 148.3 9.8 8.2e-10 38.7 0.0 13.9 12 3 4 16 16 16 8 PPR repeat family PPR_3 PF13812.6 KKK26498.1 - 6.5e-29 99.8 5.5 0.0025 17.8 0.0 11.8 7 4 4 12 12 12 7 Pentatricopeptide repeat domain PPR PF01535.20 KKK26498.1 - 4e-23 80.0 19.0 0.0011 19.0 0.0 13.4 16 1 0 16 16 16 6 PPR repeat PPR_1 PF12854.7 KKK26498.1 - 3.4e-20 71.4 0.1 1.7e-05 24.4 0.1 9.2 11 0 0 11 11 11 3 PPR repeat PPR_long PF17177.4 KKK26498.1 - 3.9e-20 72.1 16.1 9.6e-10 38.2 0.3 6.5 5 1 2 7 7 7 5 Pentacotripeptide-repeat region of PRORP RPM2 PF08579.11 KKK26498.1 - 1.4e-09 38.4 0.0 0.00026 21.4 0.0 5.5 6 0 0 6 6 6 1 Mitochondrial ribonuclease P subunit (RPM2) RPN7 PF10602.9 KKK26498.1 - 0.0034 17.1 0.4 21 4.8 0.0 3.9 3 0 0 3 3 3 0 26S proteasome subunit RPN7 ECSIT PF06239.11 KKK26498.1 - 0.0041 16.3 0.9 0.08 12.0 0.0 3.1 4 0 0 4 4 4 1 Evolutionarily conserved signalling intermediate in Toll pathway MOZART2 PF12926.7 KKK26498.1 - 0.013 15.1 0.1 0.038 13.6 0.1 1.8 1 0 0 1 1 1 0 Mitotic-spindle organizing gamma-tubulin ring associated GBP_C PF02841.14 KKK26498.1 - 2.8 7.2 6.7 13 5.1 0.0 3.3 3 0 0 3 3 3 0 Guanylate-binding protein, C-terminal domain GHMP_kinases_N PF00288.26 KKK26499.1 - 7.1e-15 55.0 3.8 1.3e-14 54.2 2.4 2.1 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KKK26499.1 - 3e-11 43.5 0.0 6.9e-11 42.4 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal PepSY_TM PF03929.16 KKK26499.1 - 0.025 14.3 0.0 0.038 13.7 0.0 1.2 1 0 0 1 1 1 0 PepSY-associated TM region DUF1206 PF06724.11 KKK26500.1 - 0.025 14.6 0.9 0.057 13.5 0.9 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1206) DUF2749 PF10907.8 KKK26500.1 - 0.19 11.9 3.7 0.18 12.0 0.7 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2749) UBA PF00627.31 KKK26501.1 - 4.6e-25 87.1 2.1 7.1e-13 48.2 0.3 2.5 2 0 0 2 2 2 2 UBA/TS-N domain XPC-binding PF09280.11 KKK26501.1 - 6.9e-24 83.3 15.5 1.2e-23 82.6 15.5 1.4 1 0 0 1 1 1 1 XPC-binding domain ubiquitin PF00240.23 KKK26501.1 - 1.8e-20 72.4 0.3 3.4e-20 71.6 0.3 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 KKK26501.1 - 4.5e-07 29.6 0.5 7.2e-07 28.9 0.5 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.6 KKK26501.1 - 0.00056 20.0 0.0 0.0011 19.0 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA_3 PF09288.10 KKK26501.1 - 0.001 18.8 0.0 0.86 9.5 0.0 2.4 2 0 0 2 2 2 2 Fungal ubiquitin-associated domain Ubiquitin_5 PF18037.1 KKK26501.1 - 0.0039 17.5 0.2 0.007 16.7 0.2 1.4 1 0 0 1 1 1 1 Ubiquitin-like domain CUE PF02845.16 KKK26501.1 - 0.0098 15.6 0.0 1.3 8.8 0.0 2.6 2 0 0 2 2 2 1 CUE domain DUF2407 PF10302.9 KKK26501.1 - 0.055 14.0 0.0 0.11 13.1 0.0 1.5 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Rap1_C PF11626.8 KKK26501.1 - 0.14 12.3 0.0 1.1 9.4 0.0 2.2 2 0 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Glyco_transf_22 PF03901.17 KKK26502.1 - 1.1e-61 209.4 23.9 1.4e-61 209.0 23.9 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family OppC_N PF12911.7 KKK26502.1 - 0.2 11.6 5.6 3 7.9 0.4 2.9 1 1 1 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C Skp1 PF01466.19 KKK26503.1 - 2.6e-28 97.9 0.5 4.7e-28 97.0 0.5 1.5 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 KKK26503.1 - 2.5e-25 88.4 0.1 6.6e-25 87.1 0.0 1.7 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain Zn_clus PF00172.18 KKK26504.1 - 5.6e-08 32.8 8.6 1.2e-07 31.7 8.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KKK26504.1 - 0.00017 20.7 0.0 0.00027 20.1 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain NAD_binding_10 PF13460.6 KKK26505.1 - 4.1e-10 39.8 0.2 1.2e-09 38.3 0.1 1.9 2 1 1 3 3 3 1 NAD(P)H-binding NmrA PF05368.13 KKK26505.1 - 1.2e-09 38.1 0.1 2.5e-06 27.2 0.1 2.7 1 1 1 3 3 3 2 NmrA-like family Epimerase PF01370.21 KKK26505.1 - 3.7e-06 26.6 0.0 5.6e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DapB_N PF01113.20 KKK26505.1 - 0.00069 19.7 0.0 0.0017 18.5 0.0 1.7 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus KR PF08659.10 KKK26505.1 - 0.0022 17.9 0.0 0.0037 17.2 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short PF00106.25 KKK26505.1 - 0.013 14.9 0.1 0.022 14.2 0.1 1.4 1 0 0 1 1 1 0 short chain dehydrogenase Semialdhyde_dh PF01118.24 KKK26505.1 - 0.024 15.1 0.0 0.044 14.2 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.17 KKK26505.1 - 0.026 13.7 0.0 0.039 13.1 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain F420_oxidored PF03807.17 KKK26505.1 - 0.091 13.3 0.5 0.23 12.1 0.5 1.7 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 KKK26505.1 - 0.11 12.6 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 KKK26505.1 - 0.11 12.3 0.3 0.23 11.3 0.3 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Ldh_1_N PF00056.23 KKK26505.1 - 0.14 12.2 0.6 0.3 11.2 0.6 1.6 1 1 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain ArAE_2_N PF10337.9 KKK26506.1 - 1.3e-69 235.4 9.6 1.3e-69 235.4 9.6 4.8 3 1 0 3 3 3 1 Putative ER transporter, 6TM, N-terminal MFS_1 PF07690.16 KKK26506.1 - 2.2e-19 69.6 48.9 2.2e-19 69.6 48.9 4.9 3 3 0 3 3 3 1 Major Facilitator Superfamily FUSC_2 PF13515.6 KKK26506.1 - 2.6e-19 69.6 10.8 2.6e-19 69.6 10.8 5.9 4 3 1 7 7 7 1 Fusaric acid resistance protein-like ArAE_2 PF10334.9 KKK26506.1 - 7.1e-14 52.2 0.0 4.3e-13 49.6 0.0 2.1 2 0 0 2 2 2 1 Aromatic acid exporter family member 2 TRI12 PF06609.13 KKK26506.1 - 1.4e-11 43.5 12.0 2.5e-11 42.7 12.0 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KKK26506.1 - 2.7e-08 33.1 10.9 2.7e-08 33.1 10.9 3.1 4 0 0 4 4 4 1 Sugar (and other) transporter ArAE_1 PF06081.11 KKK26506.1 - 0.0038 17.4 7.0 0.0038 17.4 7.0 5.0 5 1 1 6 6 6 1 Aromatic acid exporter family member 1 DPBB_1 PF03330.18 KKK26507.1 - 1.4e-07 31.7 0.0 2.3e-07 31.0 0.0 1.4 1 1 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 KKK26507.1 - 0.077 12.8 0.1 0.12 12.2 0.1 1.3 1 0 0 1 1 1 0 Barwin family Myco_arth_vir_N PF09610.10 KKK26507.1 - 0.12 12.5 1.0 0.29 11.3 1.0 1.7 1 1 0 1 1 1 0 Mycoplasma virulence signal region (Myco_arth_vir_N) Glyco_hydro_92 PF07971.12 KKK26508.1 - 2.4e-58 198.2 1.5 3.4e-58 197.7 1.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 KKK26508.1 - 1e-40 140.1 1.0 1.5e-40 139.6 1.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain Alpha-amylase_C PF02806.18 KKK26509.1 - 1.6e-26 92.6 0.0 4.9e-26 91.0 0.0 1.8 2 0 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain CBM_48 PF02922.18 KKK26509.1 - 1.3e-18 67.1 0.0 4e-18 65.5 0.0 1.9 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase PF00128.24 KKK26509.1 - 2.9e-16 60.0 0.0 9.9e-12 45.1 0.1 2.3 1 1 1 2 2 2 2 Alpha amylase, catalytic domain Amidase PF01425.21 KKK26510.1 - 7.9e-72 242.6 0.1 2.1e-70 237.9 0.0 2.4 2 1 0 2 2 2 1 Amidase ThiF PF00899.21 KKK26510.1 - 1.8e-56 191.3 0.0 3.4e-56 190.3 0.0 1.4 1 0 0 1 1 1 1 ThiF family Rhodanese PF00581.20 KKK26510.1 - 8e-10 39.2 0.0 2.1e-09 37.9 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain DAO PF01266.24 KKK26510.1 - 0.031 13.8 0.0 0.06 12.9 0.0 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase Shikimate_DH PF01488.20 KKK26510.1 - 0.055 13.5 0.0 0.17 11.9 0.0 1.9 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 KKK26510.1 - 0.065 13.7 0.0 0.29 11.6 0.0 2.0 2 0 0 2 2 2 0 Putative NAD(P)-binding ApbA PF02558.16 KKK26510.1 - 0.072 12.7 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA FAD_binding_3 PF01494.19 KKK26510.1 - 0.092 12.0 1.0 0.18 11.0 1.0 1.4 1 0 0 1 1 1 0 FAD binding domain ATP-synt_ab PF00006.25 KKK26511.1 - 1.3e-61 208.0 0.0 2.1e-61 207.3 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 KKK26511.1 - 5e-23 81.4 1.3 1.6e-22 79.8 0.8 2.1 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain ATPase PF06745.13 KKK26511.1 - 0.0035 16.7 0.2 0.0061 15.9 0.2 1.4 1 0 0 1 1 1 1 KaiC RsgA_GTPase PF03193.16 KKK26511.1 - 0.016 15.1 0.1 0.039 13.8 0.1 1.6 1 0 0 1 1 1 0 RsgA GTPase T3SS_ATPase_C PF18269.1 KKK26511.1 - 0.016 15.0 0.7 0.068 13.0 0.7 1.9 1 1 0 1 1 1 0 T3SS EscN ATPase C-terminal domain AAA PF00004.29 KKK26511.1 - 0.019 15.4 0.1 0.64 10.4 0.0 2.7 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 KKK26511.1 - 0.019 14.1 0.4 0.11 11.7 0.1 2.0 2 0 0 2 2 2 0 NB-ARC domain ATPase_2 PF01637.18 KKK26511.1 - 0.032 14.1 0.0 0.12 12.3 0.0 1.8 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_19 PF13245.6 KKK26511.1 - 0.044 14.1 0.9 0.48 10.7 0.2 2.3 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KKK26511.1 - 0.052 13.5 0.2 0.13 12.1 0.0 1.7 2 0 0 2 2 2 0 NACHT domain RNA_helicase PF00910.22 KKK26511.1 - 0.1 13.0 0.0 0.21 12.0 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_16 PF13191.6 KKK26511.1 - 0.14 12.6 0.1 0.54 10.6 0.1 2.1 1 1 0 1 1 1 0 AAA ATPase domain COX4 PF02936.14 KKK26512.1 - 1.9e-46 157.5 0.5 2.5e-46 157.1 0.5 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV DUF1104 PF06518.11 KKK26512.1 - 0.11 12.9 0.6 0.2 12.0 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1104) DUF3007 PF11460.8 KKK26512.1 - 0.19 12.0 0.8 13 6.1 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3007) DUF3106 PF11304.8 KKK26512.1 - 0.24 11.9 7.1 0.076 13.5 4.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3106) TPR_12 PF13424.6 KKK26513.1 - 7.8e-21 74.2 7.1 7.2e-09 35.8 0.2 5.6 3 2 3 6 6 6 5 Tetratricopeptide repeat TPR_10 PF13374.6 KKK26513.1 - 1.1e-11 44.2 7.3 0.044 13.7 0.1 6.3 6 0 0 6 6 6 5 Tetratricopeptide repeat DUF676 PF05057.14 KKK26513.1 - 3.8e-05 23.3 0.0 0.00016 21.2 0.0 1.9 1 1 1 2 2 2 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 KKK26513.1 - 0.00054 19.8 0.0 0.001 18.8 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein TPR_2 PF07719.17 KKK26513.1 - 0.0087 16.1 1.4 2.9 8.2 0.2 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat Abhydrolase_6 PF12697.7 KKK26513.1 - 0.01 16.4 0.1 0.023 15.3 0.0 1.8 1 1 0 1 1 1 0 Alpha/beta hydrolase family TPR_8 PF13181.6 KKK26513.1 - 0.025 14.8 1.7 3.2 8.2 0.2 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat Hydrolase_4 PF12146.8 KKK26513.1 - 0.034 13.4 0.0 0.083 12.1 0.0 1.6 2 0 0 2 2 2 0 Serine aminopeptidase, S33 TPR_1 PF00515.28 KKK26513.1 - 0.093 12.6 1.3 2.4 8.1 0.2 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 KKK26513.1 - 0.097 13.3 0.6 0.4 11.4 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Cutinase PF01083.22 KKK26513.1 - 0.1 12.6 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Cutinase tRNA-synt_2 PF00152.20 KKK26514.1 - 3.7e-66 223.4 0.0 6.3e-66 222.6 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) DUF2156 PF09924.9 KKK26514.1 - 3e-16 59.3 0.0 4.6e-16 58.7 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2156) tRNA_anti-codon PF01336.25 KKK26514.1 - 0.0002 21.3 0.0 0.00049 20.0 0.0 1.7 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 KKK26514.1 - 0.0077 15.7 0.5 2.5 7.5 0.1 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) MCM_N PF14551.6 KKK26514.1 - 0.05 14.2 0.0 0.12 12.9 0.0 1.6 1 0 0 1 1 1 0 MCM N-terminal domain Acetyltransf_6 PF13480.7 KKK26514.1 - 0.11 12.7 1.8 0.23 11.6 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Dsh_C PF12316.8 KKK26514.1 - 0.55 10.6 5.6 1 9.7 5.6 1.4 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal Tubulin PF00091.25 KKK26515.1 - 3e-67 226.7 0.0 4.6e-67 226.1 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KKK26515.1 - 3.7e-50 169.3 0.1 8.9e-50 168.1 0.1 1.7 2 0 0 2 2 2 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 KKK26515.1 - 0.0023 17.6 0.0 0.0053 16.5 0.0 1.6 1 0 0 1 1 1 1 Tubulin domain E1-E2_ATPase PF00122.20 KKK26517.1 - 2.1e-45 154.5 5.9 2.1e-45 154.5 5.9 3.0 4 0 0 4 4 4 1 E1-E2 ATPase Hydrolase PF00702.26 KKK26517.1 - 4.3e-16 59.8 0.2 1.8e-15 57.8 0.2 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KKK26517.1 - 1.8e-10 40.3 0.0 4.2e-10 39.2 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KKK26517.1 - 0.0028 17.4 0.7 0.0049 16.6 0.1 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase O-antigen_lig PF13425.6 KKK26517.1 - 0.11 11.2 5.6 0.32 9.8 5.6 1.7 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Cation_ATPase PF13246.6 KKK26517.1 - 0.2 11.8 0.0 0.42 10.7 0.0 1.5 1 0 0 1 1 1 0 Cation transport ATPase (P-type) EF-hand_4 PF12763.7 KKK26518.1 - 8.2e-37 125.3 0.0 2e-14 53.4 0.0 3.6 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 KKK26518.1 - 7.3e-09 34.6 0.0 0.002 17.5 0.0 5.2 6 0 0 6 6 6 2 EF hand EF-hand_7 PF13499.6 KKK26518.1 - 1.6e-08 34.8 0.0 0.00053 20.4 0.1 4.3 2 1 1 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.6 KKK26518.1 - 2e-07 30.4 0.1 0.49 10.5 0.0 5.8 6 0 0 6 6 6 1 EF-hand domain UBA PF00627.31 KKK26518.1 - 2.7e-07 30.3 0.0 5.7e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain DUF3450 PF11932.8 KKK26518.1 - 0.0011 18.4 9.3 0.0011 18.4 9.3 2.4 1 1 1 2 2 2 1 Protein of unknown function (DUF3450) GAS PF13851.6 KKK26518.1 - 0.0027 17.1 22.9 0.0097 15.3 9.3 2.3 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding EF-hand_8 PF13833.6 KKK26518.1 - 0.0036 17.1 0.0 0.31 10.9 0.0 3.6 3 1 1 4 4 4 1 EF-hand domain pair Spc7 PF08317.11 KKK26518.1 - 0.01 14.7 27.9 0.11 11.3 12.2 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF812 PF05667.11 KKK26518.1 - 0.02 13.8 12.5 0.033 13.1 12.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF812) FUSC PF04632.12 KKK26518.1 - 0.12 10.9 8.9 0.19 10.2 8.9 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Macoilin PF09726.9 KKK26518.1 - 0.4 9.2 15.0 0.056 12.0 8.5 2.2 2 0 0 2 2 2 0 Macoilin family DUF3584 PF12128.8 KKK26518.1 - 0.54 7.7 20.7 0.77 7.2 20.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Tup_N PF08581.10 KKK26518.1 - 0.77 10.1 11.6 0.37 11.1 5.6 2.5 1 1 1 2 2 2 0 Tup N-terminal Sulfatase_C PF14707.6 KKK26518.1 - 1.8 9.3 7.4 15 6.3 0.5 2.7 1 1 0 2 2 2 0 C-terminal region of aryl-sulfatase TPR_MLP1_2 PF07926.12 KKK26518.1 - 2.1 8.4 29.7 5.3 7.1 16.1 2.5 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein TMF_TATA_bd PF12325.8 KKK26518.1 - 2.7 8.3 23.3 0.4 10.9 6.7 3.2 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding ATG16 PF08614.11 KKK26518.1 - 3.1 8.0 31.0 7.1 6.8 15.1 2.7 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Golgin_A5 PF09787.9 KKK26518.1 - 3.1 7.2 27.0 5.6 6.3 7.2 2.1 1 1 1 2 2 2 0 Golgin subfamily A member 5 Kelch_2 PF07646.15 KKK26519.1 - 0.07 13.1 0.0 0.23 11.5 0.0 1.8 1 0 0 1 1 1 0 Kelch motif tRNA_U5-meth_tr PF05958.11 KKK26520.1 - 1.5e-11 43.9 0.0 1.3e-09 37.6 0.0 2.2 1 1 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_25 PF13649.6 KKK26520.1 - 0.0083 16.8 0.0 0.02 15.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KKK26520.1 - 0.05 13.4 0.0 0.27 11.0 0.0 2.1 3 0 0 3 3 3 0 Methyltransferase domain Ribosomal_S5_C PF03719.15 KKK26521.1 - 6.7e-26 89.5 0.1 5.8e-25 86.5 0.0 2.1 2 0 0 2 2 2 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.20 KKK26521.1 - 4e-18 65.2 0.3 1.5e-17 63.3 0.0 2.2 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain DASH_Dad3 PF08656.10 KKK26522.1 - 4.3e-26 90.8 4.6 7.9e-26 89.9 4.6 1.5 1 1 0 1 1 1 1 DASH complex subunit Dad3 Pkinase PF00069.25 KKK26523.1 - 3.9e-74 249.4 0.0 5.3e-74 248.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK26523.1 - 3.2e-30 105.3 0.0 9.6e-22 77.5 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KKK26523.1 - 8.5e-07 28.6 0.1 0.46 9.8 0.0 3.2 3 0 0 3 3 3 3 Kinase-like Pkinase_fungal PF17667.1 KKK26523.1 - 0.024 13.5 0.0 0.047 12.5 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 KKK26523.1 - 0.029 13.7 0.0 0.053 12.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KKK26523.1 - 0.085 12.8 0.0 3.3 7.5 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Lactonase PF10282.9 KKK26524.1 - 2.9e-80 270.1 0.0 4.1e-80 269.6 0.0 1.1 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller He_PIG PF05345.12 KKK26524.1 - 0.078 13.2 5.8 0.33 11.2 0.7 3.0 2 1 0 2 2 2 0 Putative Ig domain Pkr1 PF08636.10 KKK26525.1 - 5.4e-31 106.6 4.5 1.4e-30 105.2 4.5 1.8 1 0 0 1 1 1 1 ER protein Pkr1 Cullin PF00888.22 KKK26525.1 - 5.2e-24 84.8 0.2 4.3e-23 81.8 0.1 2.1 2 1 0 2 2 2 1 Cullin family ANAPC2 PF08672.11 KKK26525.1 - 3.9e-23 81.7 0.0 9.8e-23 80.4 0.0 1.8 1 0 0 1 1 1 1 Anaphase promoting complex (APC) subunit 2 DZR PF12773.7 KKK26526.1 - 0.059 13.4 0.2 0.57 10.2 0.1 2.4 2 0 0 2 2 2 0 Double zinc ribbon GFA PF04828.14 KKK26526.1 - 0.12 12.7 0.5 0.3 11.5 0.2 1.7 2 0 0 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme AAA_12 PF13087.6 KKK26527.1 - 2.9e-41 141.3 0.0 5.2e-41 140.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KKK26527.1 - 3.8e-27 95.7 0.1 4e-26 92.4 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KKK26527.1 - 3.1e-10 40.5 0.1 1.1e-08 35.5 0.0 3.0 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KKK26527.1 - 2.8e-08 33.7 0.3 0.0012 18.6 0.1 2.7 2 0 0 2 2 2 2 AAA domain DUF2075 PF09848.9 KKK26527.1 - 1.8e-05 24.1 0.2 0.14 11.4 0.0 2.4 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) ResIII PF04851.15 KKK26527.1 - 0.0004 20.4 0.0 0.00097 19.2 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.18 KKK26527.1 - 0.00064 19.5 0.3 0.69 9.6 0.0 3.1 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.6 KKK26527.1 - 0.0047 16.7 0.0 0.014 15.2 0.0 1.9 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Torus PF16131.5 KKK26527.1 - 0.13 13.0 0.8 0.96 10.2 0.2 2.4 2 0 0 2 2 2 0 Torus domain zf-CCCH PF00642.24 KKK26527.1 - 0.88 9.6 5.5 0.13 12.2 1.2 1.9 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C2H2 PF00096.26 KKK26529.1 - 8.9e-05 22.7 2.7 0.15 12.6 0.4 3.7 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KKK26529.1 - 0.00054 20.6 1.1 2.6 9.1 0.0 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KKK26529.1 - 0.084 13.3 0.0 0.24 11.9 0.0 1.8 1 0 0 1 1 1 0 Zinc-finger double domain NR_Repeat PF14046.6 KKK26529.1 - 1.7 8.8 6.8 1.1 9.4 0.4 3.2 2 1 0 2 2 2 0 Nuclear receptor repeat F-box-like PF12937.7 KKK26530.1 - 0.00015 21.6 0.1 0.00065 19.6 0.1 2.1 1 0 0 1 1 1 1 F-box-like GTP_EFTU PF00009.27 KKK26531.1 - 6.1e-09 35.7 0.0 1.4e-08 34.5 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.17 KKK26531.1 - 0.0029 17.4 0.1 0.04 13.7 0.0 2.2 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein RsgA_GTPase PF03193.16 KKK26531.1 - 0.016 15.1 1.2 2.2 8.1 0.0 2.8 2 1 0 2 2 2 0 RsgA GTPase ABC_tran PF00005.27 KKK26531.1 - 0.048 14.2 0.2 0.099 13.2 0.2 1.5 1 0 0 1 1 1 0 ABC transporter zf-C2H2_jaz PF12171.8 KKK26532.1 - 8.2e-09 35.5 0.1 1.4e-08 34.8 0.1 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KKK26532.1 - 5e-06 26.7 0.1 8.6e-06 26.0 0.1 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 KKK26532.1 - 0.00075 19.8 0.4 0.0014 19.0 0.4 1.5 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_2 PF12756.7 KKK26532.1 - 0.048 14.0 0.3 0.28 11.5 0.0 2.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 KKK26532.1 - 0.063 14.1 1.0 0.087 13.7 0.1 1.8 2 0 0 2 2 2 0 C2H2-type zinc finger FOXP-CC PF16159.5 KKK26532.1 - 0.18 12.4 1.0 0.44 11.2 0.5 1.9 1 1 1 2 2 2 0 FOXP coiled-coil domain DUF1168 PF06658.12 KKK26532.1 - 1.9 8.3 21.8 5.8 6.7 15.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1168) DUF3340 PF11818.8 KKK26532.1 - 4 7.6 17.4 5.2 7.2 10.1 2.2 2 0 0 2 2 2 0 C-terminal domain of tail specific protease (DUF3340) TFIID-18kDa PF02269.16 KKK26533.1 - 6e-32 109.5 0.5 8.9e-31 105.8 0.3 2.3 2 0 0 2 2 2 1 Transcription initiation factor IID, 18kD subunit TAFII28 PF04719.14 KKK26533.1 - 0.022 14.8 0.0 0.049 13.7 0.0 1.7 1 0 0 1 1 1 0 hTAFII28-like protein conserved region F-box PF00646.33 KKK26534.1 - 3.6e-05 23.5 1.2 0.0001 22.1 0.0 2.1 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KKK26534.1 - 5.5e-05 23.0 0.0 0.00011 22.0 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box-like_2 PF13013.6 KKK26534.1 - 0.091 12.7 0.3 0.14 12.2 0.3 1.4 1 1 0 1 1 1 0 F-box-like domain TP_methylase PF00590.20 KKK26536.1 - 1e-24 87.7 0.1 1.8e-24 86.9 0.1 1.4 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Sulfotransfer_4 PF17784.1 KKK26537.1 - 4.8e-74 248.8 0.0 5.9e-74 248.5 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KKK26537.1 - 2.2e-05 24.9 0.1 0.0022 18.4 0.1 2.4 1 1 1 2 2 2 2 Sulfotransferase family Clat_adaptor_s PF01217.20 KKK26538.1 - 7.1e-51 171.9 3.0 4.4e-50 169.3 3.0 1.8 1 1 0 1 1 1 1 Clathrin adaptor complex small chain Arylsulfotran_2 PF14269.6 KKK26539.1 - 4.5e-56 190.4 7.7 7.5e-56 189.7 7.7 1.3 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 KKK26539.1 - 3e-21 75.8 8.3 9.2e-20 70.9 8.2 2.4 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) TMEM252 PF15664.5 KKK26539.1 - 0.047 13.4 0.4 0.3 10.8 0.1 2.1 2 0 0 2 2 2 0 Transmembrane protein 252 family Tam41_Mmp37 PF09139.11 KKK26540.1 - 1.8e-128 428.6 0.0 2.1e-128 428.3 0.0 1.1 1 0 0 1 1 1 1 Phosphatidate cytidylyltransferase, mitochondrial BIR PF00653.21 KKK26541.1 - 1.4e-45 153.8 6.9 1.4e-23 83.3 0.1 2.5 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain BACK PF07707.15 KKK26542.1 - 0.031 14.4 0.0 4.1 7.6 0.0 2.1 1 1 1 2 2 2 0 BTB And C-terminal Kelch SAP PF02037.27 KKK26543.1 - 1.6e-10 40.5 0.2 3.4e-10 39.4 0.2 1.6 1 0 0 1 1 1 1 SAP domain RSB_motif PF16294.5 KKK26543.1 - 1.1e-07 32.0 0.1 1.1e-07 32.0 0.1 4.0 3 2 1 4 4 4 1 RNSP1-SAP18 binding (RSB) motif Pkinase PF00069.25 KKK26544.1 - 9.9e-30 103.8 0.0 1.3e-28 100.1 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK26544.1 - 4.5e-12 45.8 0.0 9.8e-06 25.0 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Ysc84 PF04366.12 KKK26545.1 - 1e-47 161.1 0.0 1.9e-47 160.2 0.0 1.5 1 0 0 1 1 1 1 Las17-binding protein actin regulator Flavodoxin_1 PF00258.25 KKK26546.1 - 2.8e-34 118.4 0.0 7.1e-34 117.1 0.0 1.7 2 0 0 2 2 2 1 Flavodoxin FAD_binding_1 PF00667.20 KKK26546.1 - 2.6e-29 102.4 0.0 4.4e-29 101.6 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 KKK26546.1 - 6.1e-14 52.6 0.0 1.8e-13 51.1 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 KKK26546.1 - 0.0024 18.1 0.4 0.026 14.8 0.1 2.7 2 1 1 3 3 3 2 Flavodoxin domain Flavodoxin_3 PF12641.7 KKK26546.1 - 0.0029 17.3 0.0 0.0077 15.9 0.0 1.6 2 0 0 2 2 2 1 Flavodoxin domain ETF PF01012.21 KKK26547.1 - 1.8e-43 148.5 0.4 2.2e-43 148.3 0.4 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain Ribosomal_L20 PF00453.18 KKK26547.1 - 0.029 14.4 0.0 0.049 13.7 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L20 MitMem_reg PF13012.6 KKK26548.1 - 3.5e-12 46.7 5.3 2.3e-11 44.1 3.7 2.5 2 1 0 2 2 2 1 Maintenance of mitochondrial structure and function JAB PF01398.21 KKK26548.1 - 1.6e-09 37.7 0.0 3.7e-09 36.6 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Gly_kinase PF02595.15 KKK26548.1 - 0.036 13.1 0.6 0.69 8.9 0.1 2.1 2 0 0 2 2 2 0 Glycerate kinase family RNA_pol_3_Rpc31 PF11705.8 KKK26549.1 - 8.5e-61 206.1 8.8 1.3e-60 205.5 8.8 1.3 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 SDA1 PF05285.12 KKK26549.1 - 1.3 8.4 9.1 2 7.7 9.1 1.2 1 0 0 1 1 1 0 SDA1 Solute_trans_a PF03619.16 KKK26551.1 - 1.2e-86 290.6 23.9 1.4e-86 290.4 23.9 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Brr6_like_C_C PF10104.9 KKK26551.1 - 0.26 11.0 4.9 2.2 8.1 0.6 2.7 2 1 0 2 2 2 0 Di-sulfide bridge nucleocytoplasmic transport domain DnaJ PF00226.31 KKK26552.1 - 5.8e-29 100.0 5.2 6.5e-29 99.8 5.2 1.0 1 0 0 1 1 1 1 DnaJ domain T3SchapCesA PF11439.8 KKK26552.1 - 0.071 13.2 0.2 0.14 12.4 0.1 1.5 1 1 1 2 2 2 0 Type III secretion system filament chaperone CesA Epimerase PF01370.21 KKK26553.1 - 3e-11 43.3 0.1 6.4e-05 22.5 0.2 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KKK26553.1 - 8.2e-09 35.4 0.1 1.2e-08 34.8 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KKK26553.1 - 1.3e-08 35.0 0.1 1.8e-08 34.5 0.1 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 KKK26553.1 - 2.6e-06 27.9 0.1 4.2e-06 27.2 0.1 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 KKK26553.1 - 0.00081 18.5 0.0 0.0036 16.3 0.0 1.8 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 KKK26553.1 - 0.004 16.3 0.1 0.0056 15.9 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Sacchrp_dh_NADP PF03435.18 KKK26553.1 - 0.0043 17.3 0.0 0.011 15.9 0.1 1.7 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_4 PF07993.12 KKK26553.1 - 0.0045 16.2 0.0 0.023 13.9 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein Shikimate_DH PF01488.20 KKK26553.1 - 0.031 14.3 0.0 0.095 12.8 0.0 1.9 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase Toprim PF01751.22 KKK26553.1 - 0.17 12.1 0.1 0.75 10.0 0.1 2.0 1 1 1 2 2 2 0 Toprim domain Vps5 PF09325.10 KKK26554.1 - 2.2e-13 50.3 1.3 3.3e-13 49.7 1.3 1.1 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.24 KKK26554.1 - 0.00017 21.6 0.1 0.048 13.6 0.0 2.5 1 1 1 2 2 2 2 PX domain GTP_EFTU PF00009.27 KKK26555.1 - 2.7e-56 190.2 0.0 4.5e-56 189.5 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 KKK26555.1 - 1.7e-15 56.8 0.0 9e-08 32.0 0.0 2.5 2 0 0 2 2 2 2 Elongation factor G C-terminus EFG_II PF14492.6 KKK26555.1 - 5.7e-12 45.6 0.0 1.4e-11 44.3 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 KKK26555.1 - 7.6e-06 26.2 0.0 1.5e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_IV PF03764.18 KKK26555.1 - 0.079 12.7 0.0 0.22 11.3 0.0 1.7 1 0 0 1 1 1 0 Elongation factor G, domain IV ArfGap PF01412.18 KKK26556.1 - 2.7e-29 101.6 0.0 4.5e-29 100.9 0.0 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Abhydrolase_1 PF00561.20 KKK26557.1 - 2.5e-45 155.2 0.0 6.6e-45 153.8 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KKK26557.1 - 3.8e-05 24.4 0.1 0.00035 21.3 0.1 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KKK26557.1 - 0.087 12.1 0.0 1.1 8.5 0.0 2.1 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Say1_Mug180 PF10340.9 KKK26557.1 - 0.12 11.2 0.0 0.19 10.5 0.0 1.2 1 0 0 1 1 1 0 Steryl acetyl hydrolase Glyco_hydro_3_C PF01915.22 KKK26559.1 - 9.6e-61 205.3 0.0 2.2e-60 204.1 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KKK26559.1 - 1.6e-48 165.7 0.0 2.6e-48 165.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KKK26559.1 - 2.1e-22 79.0 0.4 1.2e-21 76.6 0.4 2.2 2 0 0 2 2 2 1 Fibronectin type III-like domain PA14 PF07691.12 KKK26559.1 - 3.8e-15 56.0 0.0 7.2e-15 55.1 0.0 1.4 1 0 0 1 1 1 1 PA14 domain DUF11 PF01345.18 KKK26559.1 - 0.0051 17.1 1.1 0.042 14.1 1.1 2.3 2 0 0 2 2 2 1 Domain of unknown function DUF11 CARDB PF07705.11 KKK26559.1 - 0.025 14.8 0.1 0.063 13.5 0.1 1.6 1 0 0 1 1 1 0 CARDB THOC2_N PF16134.5 KKK26560.1 - 7.5e-252 837.5 3.8 4.6e-250 831.6 0.0 2.8 3 0 0 3 3 3 1 THO complex subunit 2 N-terminus Tho2 PF11262.8 KKK26560.1 - 2.5e-105 352.0 0.0 4.5e-105 351.1 0.0 1.5 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.8 KKK26560.1 - 1.8e-30 104.8 0.1 5.3e-30 103.3 0.0 1.9 2 0 0 2 2 2 1 Transcription- and export-related complex subunit RRM_1 PF00076.22 KKK26561.1 - 1.9e-22 78.9 0.0 9.2e-11 41.4 0.1 3.2 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KKK26561.1 - 0.00029 20.4 0.0 1.2 8.8 0.0 3.1 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 KKK26561.1 - 0.0097 16.2 0.2 4.5 7.5 0.0 3.0 2 1 0 3 3 3 1 Cytosolic domain of 10TM putative phosphate transporter RRM_7 PF16367.5 KKK26561.1 - 0.013 15.6 0.0 0.03 14.4 0.0 1.7 1 1 0 1 1 1 0 RNA recognition motif DbpA PF03880.15 KKK26561.1 - 0.13 12.3 0.1 6 6.9 0.0 2.3 2 0 0 2 2 2 0 DbpA RNA binding domain FXMRP1_C_core PF12235.8 KKK26561.1 - 0.41 11.3 12.2 0.16 12.6 9.4 1.8 2 0 0 2 2 2 0 Fragile X-related 1 protein core C terminal Peptidase_S10 PF00450.22 KKK26562.1 - 1.7e-83 281.4 2.1 2.5e-83 280.8 2.1 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase DUF3439 PF11921.8 KKK26562.1 - 1.2 9.1 9.0 0.38 10.7 5.8 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) HMGL-like PF00682.19 KKK26563.1 - 9.7e-47 159.7 0.0 1.2e-46 159.4 0.0 1.1 1 0 0 1 1 1 1 HMGL-like PE PF00934.20 KKK26563.1 - 0.1 12.9 2.3 0.21 11.9 0.2 2.3 2 0 0 2 2 2 0 PE family OSCP PF00213.18 KKK26564.1 - 2.9e-46 157.7 3.0 3.6e-46 157.4 3.0 1.1 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit Glyco_hydro_63 PF03200.16 KKK26565.1 - 2.1e-07 30.1 6.6 4e-05 22.6 0.2 4.0 4 1 0 4 4 4 2 Glycosyl hydrolase family 63 C-terminal domain Rgp1 PF08737.10 KKK26566.1 - 1.6e-137 459.1 0.0 2.5e-137 458.5 0.0 1.3 1 0 0 1 1 1 1 Rgp1 Arrestin_N PF00339.29 KKK26566.1 - 1.4e-05 25.2 0.0 3.4e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 KKK26566.1 - 0.0089 16.5 0.0 0.18 12.3 0.0 2.9 3 0 0 3 3 3 1 Arrestin (or S-antigen), C-terminal domain Spo0M PF07070.11 KKK26566.1 - 0.14 11.7 0.0 0.28 10.7 0.0 1.5 1 0 0 1 1 1 0 SpoOM protein Diphthamide_syn PF01866.17 KKK26567.1 - 2.2e-116 388.6 0.0 2.7e-116 388.3 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein SlyX PF04102.12 KKK26568.1 - 0.031 14.9 1.7 0.065 13.9 1.7 1.5 1 0 0 1 1 1 0 SlyX Bromodomain PF00439.25 KKK26569.1 - 2.1e-08 34.1 0.1 2.9e-05 24.0 0.0 3.1 3 0 0 3 3 3 2 Bromodomain WD40 PF00400.32 KKK26570.1 - 6.5e-17 61.6 7.3 0.017 16.0 0.1 8.3 9 0 0 9 9 9 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKK26570.1 - 0.0046 17.2 0.3 14 6.1 0.0 5.0 4 1 1 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Neugrin PF06413.11 KKK26571.1 - 3.3e-14 53.5 0.3 3.3e-14 53.5 0.3 1.7 2 0 0 2 2 2 1 Neugrin MRP-L20 PF12824.7 KKK26571.1 - 1.6e-05 25.1 4.6 4.3e-05 23.7 4.6 1.7 1 1 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 SPO22 PF08631.10 KKK26572.1 - 2.2e-22 79.8 6.0 3.9e-11 43.0 1.0 3.4 2 1 1 3 3 3 2 Meiosis protein SPO22/ZIP4 like TPR_8 PF13181.6 KKK26572.1 - 0.057 13.6 0.4 2.5 8.5 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat Abhydrolase_3 PF07859.13 KKK26574.1 - 2.5e-35 122.3 0.1 2.3e-24 86.4 0.0 2.6 3 0 0 3 3 3 2 alpha/beta hydrolase fold CLN3 PF02487.17 KKK26575.1 - 6.1e-162 539.2 4.4 7e-162 539.0 4.4 1.0 1 0 0 1 1 1 1 CLN3 protein MFS_1 PF07690.16 KKK26575.1 - 0.0022 17.0 21.3 0.0064 15.5 18.3 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF3671 PF12420.8 KKK26575.1 - 3.3 7.8 4.4 2.2 8.4 0.2 2.6 3 0 0 3 3 3 0 Protein of unknown function Stealth_CR2 PF11380.8 KKK26576.1 - 2.8e-35 120.7 2.1 3.8e-35 120.3 0.2 2.1 2 0 0 2 2 2 1 Stealth protein CR2, conserved region 2 Stealth_CR1 PF17101.5 KKK26576.1 - 1.9e-10 40.3 0.1 3.6e-10 39.4 0.1 1.4 1 0 0 1 1 1 1 Stealth protein CR1, conserved region 1 Stealth_CR3 PF17102.5 KKK26576.1 - 2.5e-08 33.7 0.1 5.2e-08 32.7 0.1 1.6 1 0 0 1 1 1 1 Stealth protein CR3, conserved region 3 Stealth_CR4 PF17103.5 KKK26576.1 - 0.00094 19.0 0.3 0.0031 17.3 0.3 1.9 1 0 0 1 1 1 1 Stealth protein CR4, conserved region 4 Mob1_phocein PF03637.17 KKK26577.1 - 1.3e-73 246.6 0.0 1.6e-73 246.2 0.0 1.1 1 0 0 1 1 1 1 Mob1/phocein family Abhydrolase_1 PF00561.20 KKK26578.1 - 3.7e-28 98.9 0.0 8.4e-28 97.7 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KKK26578.1 - 1.6e-14 55.0 0.0 2.1e-14 54.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KKK26578.1 - 2.2e-06 27.1 0.0 3.5e-05 23.2 0.0 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 KKK26578.1 - 0.011 14.7 0.0 0.014 14.3 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Chlorophyllase PF07224.11 KKK26578.1 - 0.047 12.7 0.0 0.068 12.2 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase AMP-binding PF00501.28 KKK26579.1 - 3e-74 250.1 0.0 4.3e-74 249.6 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 KKK26579.1 - 2.3e-60 203.9 0.0 3.6e-60 203.3 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein adh_short PF00106.25 KKK26579.1 - 1.1e-50 171.8 1.1 2.9e-50 170.5 0.9 1.8 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KKK26579.1 - 1.5e-36 126.1 0.4 1.5e-36 126.1 0.4 1.6 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KKK26579.1 - 4.8e-16 59.2 0.7 7.7e-12 45.5 0.7 2.4 2 0 0 2 2 2 2 KR domain Epimerase PF01370.21 KKK26579.1 - 3e-13 49.8 0.0 6.5e-08 32.3 0.0 2.6 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 KKK26579.1 - 3.5e-13 49.7 0.0 9.7e-13 48.3 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.19 KKK26579.1 - 2.5e-07 30.0 0.0 0.0013 17.8 0.0 3.2 3 0 0 3 3 3 2 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 KKK26579.1 - 1.5e-05 24.3 0.1 0.013 14.6 0.0 3.0 2 1 0 2 2 2 2 RmlD substrate binding domain NAD_binding_10 PF13460.6 KKK26579.1 - 0.00034 20.5 0.0 0.0029 17.5 0.1 2.5 3 0 0 3 3 3 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 KKK26579.1 - 0.00096 18.6 0.0 0.66 9.3 0.0 2.2 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase DUF4948 PF16306.5 KKK26579.1 - 0.052 13.3 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4948) AMP-binding_C PF13193.6 KKK26579.1 - 0.094 13.7 1.0 0.29 12.1 0.1 2.5 3 0 0 3 3 1 0 AMP-binding enzyme C-terminal domain ApbA PF02558.16 KKK26579.1 - 0.1 12.2 0.1 0.21 11.2 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA THF_DHG_CYH_C PF02882.19 KKK26579.1 - 0.15 11.4 0.0 0.39 10.0 0.0 1.7 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Aminotran_5 PF00266.19 KKK26580.1 - 6.5e-21 74.7 0.0 5.9e-14 51.8 0.0 3.1 1 1 1 2 2 2 2 Aminotransferase class-V Abhydrolase_6 PF12697.7 KKK26581.1 - 6.1e-12 46.6 0.0 7.9e-12 46.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KKK26581.1 - 0.0012 18.1 0.0 0.018 14.4 0.0 2.3 2 1 0 2 2 2 1 Serine aminopeptidase, S33 Lipase_2 PF01674.18 KKK26581.1 - 0.046 13.2 0.0 0.065 12.7 0.0 1.2 1 0 0 1 1 1 0 Lipase (class 2) Abhydrolase_1 PF00561.20 KKK26581.1 - 0.15 11.7 0.0 0.89 9.1 0.0 2.0 2 1 0 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_5 PF12695.7 KKK26581.1 - 0.15 11.8 0.2 0.31 10.8 0.2 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family Zip PF02535.22 KKK26582.1 - 2.9e-53 181.3 5.7 1.4e-52 179.0 5.7 1.8 1 1 0 1 1 1 1 ZIP Zinc transporter DNA_pol_phi PF04931.13 KKK26584.1 - 2e-259 862.9 19.3 2.4e-259 862.6 19.3 1.1 1 0 0 1 1 1 1 DNA polymerase phi SDA1 PF05285.12 KKK26584.1 - 0.51 9.7 21.9 1.1 8.6 21.9 1.5 1 0 0 1 1 1 0 SDA1 SLD5_C PF16922.5 KKK26585.1 - 4.7e-13 49.1 1.8 7.7e-13 48.4 1.8 1.4 1 0 0 1 1 1 1 DNA replication complex GINS protein SLD5 C-terminus Sld5 PF05916.11 KKK26585.1 - 9.1e-11 42.2 1.2 1.5e-10 41.5 1.2 1.3 1 0 0 1 1 1 1 GINS complex protein FlaF PF07309.11 KKK26585.1 - 0.024 14.7 1.7 0.043 13.8 1.7 1.3 1 0 0 1 1 1 0 Flagellar protein FlaF ILVD_EDD PF00920.21 KKK26585.1 - 0.032 12.8 0.5 0.17 10.4 0.1 1.9 2 0 0 2 2 2 0 Dehydratase family SR-25 PF10500.9 KKK26585.1 - 7.4 6.1 7.1 21 4.6 5.8 2.0 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Rhodanese PF00581.20 KKK26586.1 - 3.2e-12 46.9 0.0 6.9e-12 45.8 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain WD40 PF00400.32 KKK26587.1 - 7.2e-17 61.5 21.5 2.8e-05 24.8 0.9 10.8 10 0 0 10 10 10 6 WD domain, G-beta repeat Nucleoporin_N PF08801.11 KKK26587.1 - 0.094 11.4 0.6 1.6 7.4 0.0 3.1 3 2 1 4 4 4 0 Nup133 N terminal like PIP5K PF01504.18 KKK26588.1 - 8.9e-35 120.2 0.1 8.9e-27 94.0 0.3 2.6 1 1 1 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.24 KKK26588.1 - 4.2e-28 98.2 0.0 6.7e-28 97.6 0.0 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.21 KKK26588.1 - 1.5e-14 53.9 3.7 1.5e-14 53.9 3.7 1.9 2 0 0 2 2 2 1 FYVE zinc finger XPC-binding PF09280.11 KKK26588.1 - 0.078 12.7 0.7 0.2 11.4 0.7 1.7 1 0 0 1 1 1 0 XPC-binding domain C1_1 PF00130.22 KKK26588.1 - 1.1 9.3 10.5 0.023 14.6 3.3 2.0 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF3391 PF11871.8 KKK26588.1 - 1.3 9.6 7.2 0.2 12.2 0.2 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF3391) PK PF00224.21 KKK26589.1 - 5.8e-176 584.5 2.4 7.2e-176 584.2 2.4 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 KKK26589.1 - 1e-38 132.2 0.0 2.9e-38 130.7 0.0 1.8 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 KKK26589.1 - 0.00011 21.4 0.6 0.00027 20.2 0.3 1.7 1 1 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.25 KKK26589.1 - 0.052 12.5 0.0 0.47 9.4 0.0 2.1 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain Cellulase PF00150.18 KKK26590.1 - 3.2e-55 187.5 0.6 4.1e-55 187.2 0.6 1.0 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) SUR7 PF06687.12 KKK26591.1 - 1.6e-54 184.7 7.1 2e-54 184.5 7.1 1.1 1 0 0 1 1 1 1 SUR7/PalI family DUF348 PF03990.14 KKK26591.1 - 0.00078 19.1 1.9 0.0015 18.3 1.9 1.4 1 0 0 1 1 1 1 G5-linked-Ubiquitin-like domain DUF373 PF04123.13 KKK26591.1 - 0.0046 16.4 2.4 0.0077 15.7 2.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF373) Clc-like PF07062.12 KKK26591.1 - 0.011 15.2 3.2 0.018 14.5 3.2 1.3 1 0 0 1 1 1 0 Clc-like RICTOR_M PF14666.6 KKK26591.1 - 0.12 12.2 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, middle domain DUF5134 PF17197.4 KKK26591.1 - 0.26 11.2 7.3 0.45 10.4 7.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5134) DUF1748 PF08520.10 KKK26592.1 - 1.6e-36 124.0 0.1 1.8e-36 123.8 0.1 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) HNH_2 PF13391.6 KKK26593.1 - 1.8e-07 31.2 0.1 1.3e-06 28.4 0.1 2.1 1 1 0 1 1 1 1 HNH endonuclease LPD16 PF18830.1 KKK26593.1 - 0.17 11.9 0.0 0.27 11.2 0.0 1.4 1 0 0 1 1 1 0 Large polyvalent protein-associated domain 16 Lipase_GDSL PF00657.22 KKK26594.1 - 5e-09 36.4 0.1 6.3e-09 36.1 0.1 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase PhrC_PhrF PF11131.8 KKK26594.1 - 0.035 13.7 1.3 0.071 12.7 1.3 1.5 1 0 0 1 1 1 0 Rap-phr extracellular signalling TPP1 PF10341.9 KKK26595.1 - 0.0088 16.0 0.0 0.023 14.7 0.0 1.8 1 0 0 1 1 1 1 Shelterin complex subunit, TPP1/ACD Pil1 PF13805.6 KKK26596.1 - 5.4e-123 409.7 0.1 7e-123 409.3 0.1 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 FAM92 PF06730.11 KKK26596.1 - 0.39 10.1 3.8 0.22 10.9 1.8 1.6 2 0 0 2 2 2 0 FAM92 protein bZIP_2 PF07716.15 KKK26597.1 - 1.9e-13 50.3 13.6 4e-13 49.2 13.6 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 KKK26597.1 - 0.0012 18.8 12.3 0.0024 17.9 12.3 1.5 1 0 0 1 1 1 1 bZIP transcription factor FPP PF05911.11 KKK26597.1 - 0.037 12.2 4.7 0.051 11.8 4.7 1.1 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil DUF4094 PF13334.6 KKK26597.1 - 0.044 14.2 0.4 0.089 13.2 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) TSC22 PF01166.18 KKK26597.1 - 0.092 13.1 0.8 0.24 11.8 0.8 1.7 1 0 0 1 1 1 0 TSC-22/dip/bun family DUF3552 PF12072.8 KKK26597.1 - 0.17 11.3 9.9 0.24 10.8 9.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Fungal_trans PF04082.18 KKK26598.1 - 5.9e-21 74.7 2.3 6.8e-21 74.5 0.1 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK26598.1 - 9.7e-05 22.4 9.5 0.00016 21.7 9.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain XPG_N PF00752.17 KKK26599.1 - 2.2e-36 124.4 0.1 6.8e-36 122.8 0.0 1.9 2 0 0 2 2 2 1 XPG N-terminal domain XPG_I PF00867.18 KKK26599.1 - 1.9e-25 89.0 0.0 6.2e-25 87.4 0.0 2.0 1 0 0 1 1 1 1 XPG I-region UIM PF02809.20 KKK26599.1 - 2e-05 24.2 2.3 2e-05 24.2 2.3 3.9 3 0 0 3 3 3 2 Ubiquitin interaction motif 5_3_exonuc PF01367.20 KKK26599.1 - 0.00073 20.1 0.0 0.0027 18.3 0.0 2.0 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold Transposase_20 PF02371.16 KKK26599.1 - 0.059 13.7 0.0 0.15 12.4 0.0 1.6 1 0 0 1 1 1 0 Transposase IS116/IS110/IS902 family AA_permease_2 PF13520.6 KKK26600.1 - 2.2e-45 155.2 51.0 2.9e-45 154.9 51.0 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KKK26600.1 - 2.5e-23 82.4 46.7 3.1e-23 82.1 46.7 1.0 1 0 0 1 1 1 1 Amino acid permease Nucleos_tra2_N PF01773.20 KKK26600.1 - 0.44 11.2 6.9 0.89 10.2 0.6 3.9 3 0 0 3 3 3 0 Na+ dependent nucleoside transporter N-terminus Glyoxalase PF00903.25 KKK26601.1 - 7.5e-05 22.9 0.0 0.00025 21.2 0.0 1.7 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily ADH_N PF08240.12 KKK26602.1 - 4.8e-24 84.3 0.1 9e-24 83.5 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KKK26602.1 - 5.1e-15 55.6 0.0 1.1e-14 54.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 KKK26602.1 - 2.8e-05 23.6 0.1 6e-05 22.5 0.1 1.5 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 KKK26602.1 - 3e-05 23.4 0.1 5e-05 22.7 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 KKK26602.1 - 0.0057 16.6 0.1 0.011 15.6 0.0 1.5 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 KKK26602.1 - 0.022 15.0 0.0 0.04 14.1 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Fungal_trans PF04082.18 KKK26603.1 - 9.4e-23 80.6 0.1 1.7e-22 79.7 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK26603.1 - 7.9e-09 35.5 11.8 1.3e-08 34.8 11.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cep57_CLD_2 PF14197.6 KKK26603.1 - 0.13 12.4 1.0 0.24 11.5 1.0 1.4 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 Lzipper-MIP1 PF14389.6 KKK26603.1 - 0.13 12.6 1.0 0.44 10.9 0.3 2.2 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 Pox_A_type_inc PF04508.12 KKK26603.1 - 5.3 7.1 7.8 14 5.7 7.8 1.7 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat Ank_2 PF12796.7 KKK26605.1 - 2.3e-61 204.3 6.3 2.6e-11 43.9 0.3 7.0 2 2 4 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KKK26605.1 - 1.1e-46 156.6 8.7 4.3e-13 49.5 0.1 9.6 5 2 4 9 9 9 8 Ankyrin repeats (many copies) Ank PF00023.30 KKK26605.1 - 7.4e-38 127.4 28.6 2.7e-05 24.4 0.4 13.2 13 0 0 13 13 12 9 Ankyrin repeat Ank_5 PF13857.6 KKK26605.1 - 4.4e-37 125.7 11.0 1.6e-08 34.7 0.0 10.0 3 2 9 12 12 12 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 KKK26605.1 - 3.8e-34 112.8 10.5 0.00025 21.2 0.3 13.0 13 0 0 13 13 13 6 Ankyrin repeat AAA_16 PF13191.6 KKK26605.1 - 7.7e-06 26.4 0.0 3.1e-05 24.4 0.0 2.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KKK26605.1 - 1.6e-05 25.2 0.0 7.8e-05 23.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KKK26605.1 - 5.8e-05 23.1 0.2 0.00022 21.2 0.2 2.0 1 1 0 1 1 1 1 NACHT domain NB-ARC PF00931.22 KKK26605.1 - 0.001 18.3 0.0 0.0034 16.6 0.0 1.8 2 0 0 2 2 2 1 NB-ARC domain AAA PF00004.29 KKK26605.1 - 0.0084 16.5 0.0 0.03 14.8 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rab3-GTPase_cat PF13890.6 KKK26605.1 - 0.053 13.2 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 Rab3 GTPase-activating protein catalytic subunit C1_2 PF03107.16 KKK26605.1 - 0.24 11.7 6.5 0.53 10.7 6.5 1.5 1 0 0 1 1 1 0 C1 domain CAP_N PF01213.19 KKK26605.1 - 0.35 10.3 3.0 0.78 9.2 3.0 1.5 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal ZZ PF00569.17 KKK26605.1 - 0.46 10.3 9.5 0.89 9.4 9.5 1.4 1 0 0 1 1 1 0 Zinc finger, ZZ type MCRA PF06100.11 KKK26606.1 - 2.7e-164 547.7 0.0 3.1e-164 547.5 0.0 1.0 1 0 0 1 1 1 1 MCRA family NAD_binding_8 PF13450.6 KKK26606.1 - 6.2e-05 23.2 0.1 0.00015 21.9 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KKK26606.1 - 0.12 12.3 0.2 0.3 11.0 0.1 1.7 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 KKK26606.1 - 0.13 11.5 0.0 9.2 5.4 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KKK26606.1 - 0.16 11.6 0.1 1.2 8.6 0.1 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase Rota_NS35 PF02509.14 KKK26606.1 - 0.2 10.6 0.0 0.29 10.1 0.0 1.1 1 0 0 1 1 1 0 Rotavirus non-structural protein 35 MFS_1 PF07690.16 KKK26607.1 - 1.2e-39 136.2 43.2 2.7e-37 128.5 30.0 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KKK26607.1 - 2.4e-11 43.2 12.7 2.9e-11 42.9 12.7 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter Trp_oprn_chp PF09534.10 KKK26607.1 - 0.028 14.2 0.3 0.028 14.2 0.3 1.8 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) NEMP PF10225.9 KKK26607.1 - 2.8 7.5 11.7 0.17 11.5 6.2 1.7 2 0 0 2 2 2 0 NEMP family MFS_1 PF07690.16 KKK26608.1 - 2.4e-18 66.2 51.1 2.8e-18 66.0 50.4 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily FMO-like PF00743.19 KKK26609.1 - 7.9e-17 60.9 0.2 3.7e-15 55.3 0.0 2.6 2 2 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KKK26609.1 - 7.1e-13 48.4 0.0 2.6e-10 40.0 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KKK26609.1 - 3.8e-12 46.1 0.0 2.5e-11 43.4 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KKK26609.1 - 1.5e-10 40.7 0.0 1.4e-09 37.5 0.0 2.4 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KKK26609.1 - 9.7e-09 35.3 0.0 7.1e-07 29.4 0.0 3.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KKK26609.1 - 0.00091 19.7 0.3 2.9 8.5 0.2 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KKK26609.1 - 0.0012 18.0 1.5 0.0035 16.5 0.0 2.4 3 1 0 3 3 3 1 Lycopene cyclase protein DAO PF01266.24 KKK26609.1 - 0.0024 17.5 0.5 0.051 13.1 0.0 2.6 3 1 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KKK26609.1 - 0.0027 16.9 0.0 0.0048 16.0 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 KKK26609.1 - 0.0054 16.0 0.5 0.017 14.4 0.1 1.9 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.14 KKK26609.1 - 0.011 14.4 0.2 0.042 12.5 0.0 1.9 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_9 PF13454.6 KKK26609.1 - 0.053 13.5 1.2 5.5 7.0 0.0 3.5 3 1 0 3 3 3 0 FAD-NAD(P)-binding DUF4034 PF13226.6 KKK26611.1 - 0.0084 15.5 0.0 0.0093 15.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4034) APH PF01636.23 KKK26612.1 - 2.6e-11 43.9 0.0 5.8e-10 39.5 0.0 2.6 2 1 0 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.20 KKK26612.1 - 0.0017 17.7 0.0 0.0028 17.0 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase Isy1 PF06246.12 KKK26613.1 - 1.3e-78 264.1 0.2 1.5e-78 264.0 0.2 1.0 1 0 0 1 1 1 1 Isy1-like splicing family YolD PF08863.10 KKK26613.1 - 0.0097 15.9 0.0 0.019 15.0 0.0 1.5 1 0 0 1 1 1 1 YolD-like protein SH3_1 PF00018.28 KKK26614.1 - 1.6e-11 43.6 0.0 3.4e-11 42.6 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KKK26614.1 - 2.6e-09 36.8 0.1 5.2e-09 35.8 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KKK26614.1 - 2e-06 27.4 0.0 3.8e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain HMG-CoA_red PF00368.18 KKK26615.1 - 1.6e-137 458.5 8.1 2e-137 458.1 8.1 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase HPIH PF13323.6 KKK26615.1 - 9.8e-55 184.7 0.4 1.6e-54 184.0 0.4 1.3 1 0 0 1 1 1 1 N-terminal domain with HPIH motif Sterol-sensing PF12349.8 KKK26615.1 - 2.2e-13 50.3 3.5 6.1e-13 48.9 2.5 2.3 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 KKK26615.1 - 8.4e-08 30.8 4.5 1.5e-07 30.0 4.5 1.3 1 0 0 1 1 1 1 Patched family DUF952 PF06108.12 KKK26616.1 - 1.2e-20 73.3 0.0 1.6e-20 72.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF952) IMPDH PF00478.25 KKK26617.1 - 1.3e-126 422.3 4.0 1.5e-126 422.1 4.0 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 KKK26617.1 - 1.1e-18 67.4 0.0 7e-10 39.2 0.0 2.5 2 0 0 2 2 2 2 CBS domain NMO PF03060.15 KKK26617.1 - 2.5e-05 23.9 4.0 0.065 12.6 4.3 2.7 2 1 1 3 3 3 2 Nitronate monooxygenase FMN_dh PF01070.18 KKK26617.1 - 5.4e-05 22.4 0.5 0.00015 21.0 0.5 1.8 1 0 0 1 1 1 1 FMN-dependent dehydrogenase His_biosynth PF00977.21 KKK26617.1 - 0.00062 19.3 2.7 0.0068 15.9 2.7 2.1 1 1 0 1 1 1 1 Histidine biosynthesis protein YpsA PF06908.11 KKK26617.1 - 0.0048 16.9 0.0 0.0092 16.0 0.0 1.4 1 0 0 1 1 1 1 YspA SLOG family PK PF00224.21 KKK26617.1 - 0.042 12.7 0.0 0.11 11.3 0.0 1.6 1 1 1 2 2 2 0 Pyruvate kinase, barrel domain RasGAP PF00616.19 KKK26618.1 - 2e-53 181.2 0.0 7.3e-53 179.4 0.0 2.0 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 KKK26618.1 - 1.3e-49 167.9 4.8 1.3e-49 167.9 4.8 3.2 3 1 0 3 3 3 1 RasGAP C-terminus CH PF00307.31 KKK26618.1 - 7.5e-11 42.2 0.0 5e-10 39.5 0.0 2.3 2 0 0 2 2 2 1 Calponin homology (CH) domain IQ PF00612.27 KKK26618.1 - 9.7e-08 31.2 50.3 0.21 11.5 0.0 14.6 16 0 0 16 16 16 4 IQ calmodulin-binding motif Trypan_PARP PF05887.11 KKK26618.1 - 0.012 15.5 0.1 0.012 15.5 0.1 1.7 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) ENTH PF01417.20 KKK26620.1 - 3e-45 153.3 0.1 4.2e-45 152.8 0.1 1.2 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 KKK26620.1 - 2.9e-05 23.2 0.0 4.3e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 ANTH domain VHS PF00790.19 KKK26620.1 - 0.053 13.4 0.1 0.092 12.6 0.1 1.4 1 0 0 1 1 1 0 VHS domain DUF5102 PF17104.5 KKK26620.1 - 0.1 12.6 4.6 2.8 7.9 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5102) NUDIX PF00293.28 KKK26621.1 - 3.5e-07 30.3 0.0 1.2e-06 28.6 0.0 1.9 1 1 0 1 1 1 1 NUDIX domain TRH PF05438.12 KKK26621.1 - 0.078 12.7 0.1 0.14 11.9 0.1 1.3 1 0 0 1 1 1 0 Thyrotropin-releasing hormone (TRH) Ribosomal_S21e PF01249.18 KKK26622.1 - 5.8e-42 141.7 0.1 6.5e-42 141.5 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e tRNA-synt_2d PF01409.20 KKK26623.1 - 3.1e-88 295.4 0.0 4.2e-88 295.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) PheRS_DBD3 PF18553.1 KKK26623.1 - 8.9e-15 54.7 0.7 1.6e-14 53.9 0.1 1.8 2 0 0 2 2 2 1 PheRS DNA binding domain 3 tRNA_synthFbeta PF17759.1 KKK26623.1 - 1.1e-06 28.2 0.0 0.011 15.2 0.0 2.3 2 0 0 2 2 2 2 Phenylalanyl tRNA synthetase beta chain CLM domain tRNA-synt_2 PF00152.20 KKK26623.1 - 2.9e-05 23.3 0.4 0.0023 17.1 0.0 3.3 4 0 0 4 4 4 1 tRNA synthetases class II (D, K and N) PheRS_DBD2 PF18554.1 KKK26623.1 - 0.0011 18.9 2.2 0.0032 17.4 2.2 1.9 1 0 0 1 1 1 1 PheRS DNA binding domain 2 tRNA-synt_2b PF00587.25 KKK26623.1 - 0.16 11.9 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 tRNA synthetase class II core domain (G, H, P, S and T) HAMP PF00672.25 KKK26624.1 - 2.3e-44 149.5 14.5 4.3e-09 36.6 0.0 7.3 6 1 0 6 6 6 5 HAMP domain HATPase_c PF02518.26 KKK26624.1 - 3.4e-32 111.3 0.1 1.5e-31 109.2 0.1 2.2 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KKK26624.1 - 4.2e-27 94.5 0.6 2e-26 92.3 0.6 2.3 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 KKK26624.1 - 8.4e-17 61.0 3.5 3.1e-16 59.2 0.2 3.8 4 0 0 4 4 3 1 His Kinase A (phospho-acceptor) domain Syntaxin_2 PF14523.6 KKK26624.1 - 1e-05 25.9 21.8 1.2 9.6 0.1 7.2 3 2 2 6 6 6 2 Syntaxin-like protein DUF4279 PF14106.6 KKK26624.1 - 7.7e-05 22.9 0.0 7.8 6.7 0.0 5.3 5 1 0 5 5 5 1 Domain of unknown function (DUF4279) DUF1843 PF08898.10 KKK26624.1 - 0.00055 20.4 6.3 16 6.1 0.1 6.0 5 1 0 5 5 5 0 Domain of unknown function (DUF1843) DUF948 PF06103.11 KKK26624.1 - 0.007 16.6 58.5 1 9.6 0.3 10.2 4 2 3 7 7 7 4 Bacterial protein of unknown function (DUF948) SpoIIID PF12116.8 KKK26624.1 - 0.032 14.3 4.8 23 5.1 0.0 5.3 5 0 0 5 5 5 0 Stage III sporulation protein D Fib_alpha PF08702.10 KKK26624.1 - 0.04 14.1 37.4 1.2 9.4 0.6 7.4 6 1 1 7 7 7 0 Fibrinogen alpha/beta chain family NOD PF06816.13 KKK26624.1 - 0.049 13.3 0.0 6.4 6.5 0.0 2.7 2 0 0 2 2 2 0 NOTCH protein Cbl_N PF02262.16 KKK26624.1 - 0.074 13.1 0.5 5.2 7.1 0.3 3.1 3 0 0 3 3 3 0 CBL proto-oncogene N-terminal domain 1 IcmF_C PF06744.12 KKK26624.1 - 0.076 12.6 0.1 0.28 10.8 0.1 2.0 1 0 0 1 1 1 0 Type VI secretion protein IcmF C-terminal CMD PF02627.20 KKK26624.1 - 0.15 12.1 1.2 17 5.6 0.0 4.0 5 0 0 5 5 4 0 Carboxymuconolactone decarboxylase family DUF3829 PF12889.7 KKK26624.1 - 0.19 11.2 19.0 0.35 10.3 0.8 5.3 3 3 3 6 6 6 0 Protein of unknown function (DUF3829) BORCS6 PF10157.9 KKK26624.1 - 0.59 10.3 15.1 6 7.1 0.1 5.7 3 2 1 5 5 5 0 BLOC-1-related complex sub-unit 6 Gp-FAR-1 PF05823.12 KKK26624.1 - 0.77 10.1 12.1 14 6.0 0.2 5.1 2 1 2 6 6 5 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) DUF4795 PF16043.5 KKK26624.1 - 0.9 9.1 30.7 1.7 8.2 7.2 4.9 1 1 1 3 3 3 0 Domain of unknown function (DUF4795) WXG100 PF06013.12 KKK26624.1 - 1.5 9.1 32.5 2 8.7 0.3 8.4 7 3 2 9 9 9 0 Proteins of 100 residues with WXG Mer2 PF09074.10 KKK26624.1 - 3.5 7.4 39.2 3.3 7.5 3.6 6.1 3 1 2 5 5 5 0 Mer2 GLE1 PF07817.13 KKK26624.1 - 9.1 5.4 14.4 9.3 5.4 1.0 4.7 3 1 2 5 5 5 0 GLE1-like protein Sugar_tr PF00083.24 KKK26625.1 - 5.2e-23 81.6 9.3 6.5e-23 81.3 9.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKK26625.1 - 6.4e-15 54.9 12.9 8.1e-15 54.6 12.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.6 KKK26625.1 - 5.1e-05 22.0 4.9 5.6e-05 21.9 4.9 1.2 1 0 0 1 1 1 1 MFS/sugar transport protein TRI12 PF06609.13 KKK26625.1 - 0.00011 20.8 1.9 0.00014 20.5 1.9 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 KKK26625.1 - 0.00062 18.2 6.6 0.074 11.3 0.6 2.0 1 1 1 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family PTR2 PF00854.21 KKK26625.1 - 0.0042 16.0 5.0 0.14 11.0 1.4 2.1 1 1 1 2 2 2 2 POT family O-antigen_lig PF13425.6 KKK26625.1 - 0.15 10.9 4.0 0.19 10.5 4.0 1.2 1 0 0 1 1 1 0 O-antigen ligase like membrane protein YtpI PF14007.6 KKK26625.1 - 4.6 7.4 7.5 4.2 7.6 6.0 1.7 1 1 1 2 2 2 0 YtpI-like protein DUF2371 PF10177.9 KKK26625.1 - 7.3 6.8 5.5 16 5.6 5.5 1.5 1 1 0 1 1 1 0 Uncharacterised conserved protein (DUF2371) Pyr_redox_2 PF07992.14 KKK26626.1 - 5.4e-11 42.3 0.0 6.7e-09 35.4 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KKK26626.1 - 0.0027 17.4 0.3 0.0069 16.0 0.2 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KKK26626.1 - 0.0084 16.1 0.0 0.057 13.4 0.0 2.1 2 0 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KKK26626.1 - 0.13 12.5 0.1 0.35 11.1 0.1 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KKK26626.1 - 0.14 11.2 1.2 0.18 10.8 0.3 1.7 2 1 0 2 2 2 0 Lycopene cyclase protein Lactamase_B PF00753.27 KKK26627.1 - 2.5e-19 70.1 0.8 3.7e-19 69.5 0.8 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KKK26627.1 - 0.005 16.4 0.1 0.008 15.7 0.1 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain NAD_binding_1 PF00175.21 KKK26628.1 - 6.7e-13 49.2 0.0 1.8e-12 47.8 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Globin PF00042.22 KKK26628.1 - 2.1e-08 34.7 0.1 7.1e-08 33.0 0.0 2.0 3 0 0 3 3 3 1 Globin FAD_binding_6 PF00970.24 KKK26628.1 - 5.9e-06 26.6 0.0 9.5e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Protoglobin PF11563.8 KKK26628.1 - 0.002 18.0 0.1 0.0061 16.5 0.1 1.7 1 1 0 1 1 1 1 Protoglobin NAD_binding_6 PF08030.12 KKK26628.1 - 0.054 13.6 0.0 0.36 10.9 0.0 2.2 2 1 1 3 3 3 0 Ferric reductase NAD binding domain MIP PF00230.20 KKK26629.1 - 2.7e-38 131.9 13.4 2.6e-24 86.2 7.1 2.1 2 0 0 2 2 2 2 Major intrinsic protein Bact_transglu_N PF08379.10 KKK26629.1 - 0.48 11.4 1.4 1.1 10.2 0.3 2.0 2 0 0 2 2 2 0 Bacterial transglutaminase-like N-terminal region AA_permease_2 PF13520.6 KKK26630.1 - 1.1e-61 209.0 52.9 2.1e-61 208.0 32.9 2.1 2 0 0 2 2 2 2 Amino acid permease RIFIN PF02009.16 KKK26631.1 - 0.28 11.0 1.5 0.33 10.8 1.5 1.2 1 0 0 1 1 1 0 Rifin MID_MedPIWI PF18296.1 KKK26631.1 - 0.51 10.1 3.6 0.65 9.7 3.6 1.1 1 0 0 1 1 1 0 MID domain of medPIWI Tmemb_cc2 PF10267.9 KKK26631.1 - 1.1 8.3 5.9 1.4 8.0 5.9 1.0 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Anoctamin PF04547.12 KKK26632.1 - 6.5e-97 325.2 5.8 7.8e-97 324.9 5.8 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel ArabFuran-catal PF09206.11 KKK26633.1 - 2.3e-150 500.2 13.0 2.3e-150 500.2 13.0 1.4 2 0 0 2 2 2 1 Alpha-L-arabinofuranosidase B, catalytic AbfB PF05270.13 KKK26633.1 - 9.6e-59 197.4 1.7 1.4e-58 196.9 1.7 1.2 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase B (ABFB) domain GPI-anchored PF10342.9 KKK26635.1 - 1.5e-19 70.6 2.6 1.5e-19 70.6 2.6 2.2 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF1593 PF07632.11 KKK26636.1 - 3.2e-74 249.6 0.0 5.1e-74 249.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1593) Pro-kuma_activ PF09286.11 KKK26637.1 - 4.1e-30 104.9 0.3 8.4e-29 100.7 0.0 2.7 3 0 0 3 3 3 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 KKK26637.1 - 0.0059 15.9 0.0 0.015 14.6 0.0 1.6 1 1 0 1 1 1 1 Subtilase family FAD_binding_4 PF01565.23 KKK26638.1 - 1.6e-19 70.0 1.8 3e-19 69.1 1.8 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KKK26638.1 - 1.9e-06 27.9 0.0 4.9e-06 26.5 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like Maf PF02545.14 KKK26638.1 - 0.018 14.9 0.0 0.031 14.1 0.0 1.3 1 0 0 1 1 1 0 Maf-like protein TyeA PF09059.10 KKK26638.1 - 0.067 13.3 0.0 0.18 11.9 0.0 1.7 2 0 0 2 2 2 0 TyeA FAD_binding_4 PF01565.23 KKK26639.1 - 4.7e-19 68.5 0.1 9.8e-19 67.5 0.1 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KKK26639.1 - 5.5e-09 36.0 0.3 1.4e-08 34.7 0.3 1.7 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.10 KKK26639.1 - 0.11 11.9 0.1 0.17 11.3 0.1 1.2 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding Ecm33 PF12454.8 KKK26639.1 - 1.6 9.0 5.6 7.6 6.8 3.5 2.6 2 0 0 2 2 2 0 GPI-anchored cell wall organization protein DUF4131 PF13567.6 KKK26641.1 - 3 7.5 8.9 0.71 9.5 1.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) PH PF00169.29 KKK26642.1 - 7e-10 39.4 0.0 6.6e-09 36.2 0.0 2.4 1 1 0 1 1 1 1 PH domain SH3_1 PF00018.28 KKK26642.1 - 7.6e-10 38.3 0.0 1.4e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KKK26642.1 - 1.3e-09 37.8 0.1 2.8e-09 36.7 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SAM_2 PF07647.17 KKK26642.1 - 5.5e-09 36.0 0.1 9.5e-09 35.3 0.1 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_2 PF07653.17 KKK26642.1 - 2.4e-05 23.9 0.1 4.8e-05 23.0 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain PH_11 PF15413.6 KKK26642.1 - 0.0089 16.4 0.0 0.022 15.2 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 KKK26642.1 - 0.05 13.9 0.0 0.14 12.5 0.0 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain zf-MIZ PF02891.20 KKK26643.1 - 9.4e-12 44.5 0.2 1.7e-11 43.7 0.2 1.4 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 KKK26643.1 - 0.00093 19.0 0.1 0.002 17.9 0.1 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit DUF5102 PF17104.5 KKK26644.1 - 9.8e-109 363.8 2.0 1.4e-108 363.3 2.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF5102) FEZ PF07763.13 KKK26644.1 - 0.0062 16.3 0.0 0.37 10.5 0.0 2.2 2 0 0 2 2 2 2 FEZ-like protein Nsp1_C PF05064.13 KKK26645.1 - 9.4e-43 144.7 1.2 9.4e-43 144.7 1.2 1.7 2 0 0 2 2 2 1 Nsp1-like C-terminal region Nucleoporin_FG PF13634.6 KKK26645.1 - 6.5e-08 33.3 154.9 2.7e-06 28.1 24.8 7.3 1 1 5 6 6 5 4 Nucleoporin FG repeat region ParB PF08775.10 KKK26645.1 - 0.0043 17.5 0.7 0.011 16.2 0.7 1.6 1 0 0 1 1 1 1 ParB family SGT1 PF07093.11 KKK26645.1 - 0.034 12.6 3.0 0.044 12.2 3.0 1.1 1 0 0 1 1 1 0 SGT1 protein EzrA PF06160.12 KKK26645.1 - 0.19 9.8 8.1 0.23 9.6 0.6 2.0 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA DUF1664 PF07889.12 KKK26645.1 - 0.2 11.7 7.1 0.95 9.5 0.9 2.7 1 1 0 3 3 3 0 Protein of unknown function (DUF1664) Snapin_Pallidin PF14712.6 KKK26645.1 - 0.27 11.7 6.3 3.4 8.2 0.1 2.6 3 0 0 3 3 2 0 Snapin/Pallidin DUF4200 PF13863.6 KKK26645.1 - 0.28 11.6 11.8 0.5 10.8 5.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) OmpH PF03938.14 KKK26645.1 - 0.44 10.9 10.4 1 9.7 0.2 2.3 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) TACC_C PF05010.14 KKK26645.1 - 0.72 9.6 9.5 0.22 11.3 2.9 2.1 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal DUF724 PF05266.14 KKK26645.1 - 0.88 9.4 6.8 1.7 8.4 1.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF724) DUF16 PF01519.16 KKK26645.1 - 0.99 9.9 7.1 0.82 10.2 0.3 2.7 1 1 2 3 3 3 0 Protein of unknown function DUF16 Laminin_II PF06009.12 KKK26645.1 - 1.5 8.8 8.7 4.2 7.4 0.7 2.6 1 1 2 3 3 3 0 Laminin Domain II GAS PF13851.6 KKK26645.1 - 1.7 8.0 10.4 2.1 7.6 0.4 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding FapA PF03961.13 KKK26645.1 - 2 6.9 6.6 4.1 5.9 0.6 2.1 1 1 1 2 2 2 0 Flagellar Assembly Protein A AAA_13 PF13166.6 KKK26645.1 - 2.3 6.8 7.7 0.74 8.4 2.8 1.7 1 1 1 2 2 2 0 AAA domain WXG100 PF06013.12 KKK26645.1 - 2.9 8.2 5.9 1.1 9.5 0.4 2.9 2 1 0 3 3 3 0 Proteins of 100 residues with WXG BLOC1_2 PF10046.9 KKK26645.1 - 3.1 8.2 7.6 7 7.0 0.6 2.6 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 MscS_porin PF12795.7 KKK26645.1 - 3.4 7.1 13.2 3.3 7.2 1.6 2.3 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain HIP1_clath_bdg PF16515.5 KKK26645.1 - 4.3 8.0 13.8 3.6 8.3 0.9 2.9 1 1 1 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 FlaC_arch PF05377.11 KKK26645.1 - 4.5 7.7 8.8 1.6 9.2 0.3 3.0 4 0 0 4 4 3 0 Flagella accessory protein C (FlaC) IFT57 PF10498.9 KKK26645.1 - 4.6 6.1 12.6 0.58 9.1 4.0 2.0 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 ERM PF00769.19 KKK26645.1 - 4.6 7.0 11.5 7.3 6.3 11.5 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Spc7 PF08317.11 KKK26645.1 - 6 5.7 14.4 2.7 6.8 5.4 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein IATP PF04568.12 KKK26646.1 - 1.4e-27 96.0 1.1 1.6e-27 95.8 1.1 1.0 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP PKHD_C PF18331.1 KKK26646.1 - 0.11 12.6 0.2 0.18 11.9 0.2 1.4 1 0 0 1 1 1 0 PKHD-type hydroxylase C-terminal domain 14-3-3 PF00244.20 KKK26647.1 - 1.5e-105 351.6 4.6 1.7e-105 351.4 4.6 1.0 1 0 0 1 1 1 1 14-3-3 protein Orbi_VP5 PF00901.17 KKK26647.1 - 0.11 10.8 3.0 0.17 10.3 3.0 1.2 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 BUD22 PF09073.10 KKK26648.1 - 0.0013 18.2 9.4 0.0018 17.7 9.4 1.1 1 0 0 1 1 1 1 BUD22 Tub_N PF16322.5 KKK26648.1 - 0.028 14.8 7.6 0.048 14.1 7.6 1.3 1 0 0 1 1 1 0 Tubby N-terminal Kin17_mid PF10357.9 KKK26648.1 - 0.084 12.8 2.3 6.6 6.7 0.2 2.3 2 0 0 2 2 2 0 Domain of Kin17 curved DNA-binding protein Sigma70_ner PF04546.13 KKK26648.1 - 0.47 10.3 9.4 1.1 9.1 1.2 2.2 2 0 0 2 2 2 0 Sigma-70, non-essential region RXT2_N PF08595.11 KKK26648.1 - 0.51 10.3 6.0 3.2 7.7 0.7 2.2 2 0 0 2 2 2 0 RXT2-like, N-terminal TFIIF_alpha PF05793.12 KKK26648.1 - 0.68 8.4 13.4 0.51 8.9 3.1 2.1 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) FAM176 PF14851.6 KKK26648.1 - 1.7 8.3 10.8 2.9 7.6 1.5 2.3 2 0 0 2 2 2 0 FAM176 family DUF1738 PF08401.11 KKK26648.1 - 8.7 6.5 7.7 33 4.6 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1738) PIEZO PF15917.5 KKK26648.1 - 8.9 5.7 8.4 0.76 9.2 0.9 2.1 2 0 0 2 2 2 0 Piezo Ank_4 PF13637.6 KKK26650.1 - 3.7e-12 46.5 1.5 1.8e-08 34.7 0.1 4.3 3 1 1 4 4 4 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KKK26650.1 - 3.5e-06 27.5 0.2 0.013 16.1 0.1 3.4 2 1 3 5 5 5 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KKK26650.1 - 0.00057 20.1 2.0 0.2 12.3 0.1 4.2 4 1 0 4 4 4 1 Ankyrin repeat Ank_5 PF13857.6 KKK26650.1 - 0.0039 17.5 1.4 0.16 12.3 0.1 3.2 3 0 0 3 3 3 1 Ankyrin repeats (many copies) KilA-N PF04383.13 KKK26650.1 - 0.006 16.4 0.3 0.045 13.6 0.3 2.3 1 1 0 1 1 1 1 KilA-N domain Baculo_PEP_C PF04513.12 KKK26650.1 - 0.013 15.5 1.1 0.022 14.8 0.3 1.7 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus TFR_dimer PF04253.15 KKK26650.1 - 0.2 11.7 1.0 0.59 10.3 1.0 1.7 1 0 0 1 1 1 0 Transferrin receptor-like dimerisation domain IMD PF08397.11 KKK26650.1 - 0.42 10.0 2.8 0.8 9.0 2.8 1.4 1 0 0 1 1 1 0 IRSp53/MIM homology domain Ank PF00023.30 KKK26650.1 - 1.1 9.8 2.7 35 5.1 0.1 3.7 3 0 0 3 3 3 0 Ankyrin repeat HAUS-augmin3 PF14932.6 KKK26650.1 - 5.2 6.6 8.9 3.6 7.1 3.7 2.2 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 SnAPC_2_like PF11035.8 KKK26651.1 - 0.019 15.2 0.2 0.14 12.3 0.0 2.2 2 0 0 2 2 2 0 Small nuclear RNA activating complex subunit 2, SNAP190 Myb ResIII PF04851.15 KKK26652.1 - 3.8e-25 88.9 0.0 1.1e-22 80.9 0.0 3.2 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KKK26652.1 - 4.6e-15 55.9 0.0 4.2e-14 52.8 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KKK26652.1 - 1.3e-11 44.6 0.0 5.4e-11 42.6 0.0 2.1 2 1 0 2 2 2 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 KKK26652.1 - 1e-06 28.6 0.0 3.7e-06 26.8 0.0 1.9 2 0 0 2 2 2 1 SWI2/SNF2 ATPase DUF2075 PF09848.9 KKK26652.1 - 0.0075 15.6 0.0 0.015 14.5 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Sugar_tr PF00083.24 KKK26653.1 - 7.4e-38 130.6 23.1 1.4e-36 126.3 23.1 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKK26653.1 - 8.5e-29 100.6 53.3 2.4e-27 95.8 34.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily PGAP1 PF07819.13 KKK26654.1 - 4.6e-90 301.4 0.0 7.7e-90 300.6 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 KKK26654.1 - 5.7e-06 27.1 0.1 1.4e-05 25.8 0.1 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Palm_thioest PF02089.15 KKK26654.1 - 0.00024 21.0 0.0 0.0004 20.3 0.0 1.4 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_1 PF00561.20 KKK26654.1 - 0.00096 18.9 0.0 0.0026 17.5 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF676 PF05057.14 KKK26654.1 - 0.0027 17.2 0.0 0.0052 16.3 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Esterase PF00756.20 KKK26654.1 - 0.0063 16.2 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.8 KKK26654.1 - 0.014 14.7 0.0 0.029 13.6 0.0 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 LCAT PF02450.15 KKK26654.1 - 0.08 12.1 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Lipase_3 PF01764.25 KKK26654.1 - 0.13 12.2 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) FAD_binding_3 PF01494.19 KKK26655.1 - 1e-20 74.3 0.0 1.4e-20 73.8 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KKK26655.1 - 1.2e-08 35.0 3.2 0.0012 18.5 1.0 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 KKK26655.1 - 7.7e-07 29.6 0.5 3.3e-05 24.4 0.0 2.7 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KKK26655.1 - 1.4e-06 27.7 0.8 1.4e-06 27.7 0.8 1.5 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 KKK26655.1 - 1.5e-06 27.7 2.4 7.5 5.7 0.3 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KKK26655.1 - 3.4e-06 27.2 0.4 9.8e-06 25.7 0.4 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KKK26655.1 - 6.6e-06 25.1 0.9 0.00027 19.8 0.1 2.1 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.22 KKK26655.1 - 0.0001 21.5 0.1 0.00031 20.0 0.1 1.7 1 1 0 2 2 2 1 Glucose inhibited division protein A Trp_halogenase PF04820.14 KKK26655.1 - 0.00017 20.6 1.5 0.0062 15.4 0.0 2.2 2 0 0 2 2 2 1 Tryptophan halogenase Lycopene_cycl PF05834.12 KKK26655.1 - 0.00048 19.3 1.3 0.057 12.4 0.3 2.1 2 0 0 2 2 2 2 Lycopene cyclase protein FAD_oxidored PF12831.7 KKK26655.1 - 0.0013 18.2 1.0 0.0016 17.9 0.2 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KKK26655.1 - 0.0021 17.3 0.4 0.0038 16.5 0.4 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KKK26655.1 - 0.0081 15.4 0.1 0.017 14.4 0.1 1.4 1 0 0 1 1 1 1 Thi4 family 3HCDH_N PF02737.18 KKK26655.1 - 0.1 12.5 0.2 0.17 11.7 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 KKK26655.1 - 0.11 11.8 0.1 0.23 10.7 0.1 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Dehydrin PF00257.19 KKK26656.1 - 0.00016 22.2 4.6 0.00016 22.2 4.6 1.8 2 0 0 2 2 2 1 Dehydrin Rick_17kDa_Anti PF05433.15 KKK26656.1 - 0.0017 18.2 20.6 0.0031 17.3 20.6 1.4 1 0 0 1 1 1 1 Glycine zipper 2TM domain DUF2076 PF09849.9 KKK26656.1 - 0.013 15.5 16.2 0.013 15.5 16.2 2.9 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) DUF533 PF04391.12 KKK26656.1 - 0.1 12.2 3.9 0.17 11.4 3.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF533) DUF755 PF05501.11 KKK26656.1 - 0.8 10.0 19.6 1.3 9.3 19.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF755) RuBisCO_large PF00016.20 KKK26656.1 - 0.82 8.8 6.5 1.1 8.4 6.5 1.1 1 0 0 1 1 1 0 Ribulose bisphosphate carboxylase large chain, catalytic domain NMD3 PF04981.13 KKK26657.1 - 1e-77 260.9 3.2 1.3e-77 260.5 3.2 1.2 1 0 0 1 1 1 1 NMD3 family DZR PF12773.7 KKK26657.1 - 0.38 10.8 7.9 69 3.6 7.9 2.8 1 1 0 1 1 1 0 Double zinc ribbon DUF35_N PF12172.8 KKK26657.1 - 0.77 9.7 11.5 1.6 8.6 0.1 3.4 4 0 0 4 4 4 0 Rubredoxin-like zinc ribbon domain (DUF35_N) FYVE PF01363.21 KKK26657.1 - 5.1 7.3 6.6 11 6.2 3.4 2.6 2 1 0 2 2 2 0 FYVE zinc finger Oxidored_q4 PF00507.19 KKK26658.1 - 0.15 12.3 4.1 0.46 10.7 0.1 2.8 3 0 0 3 3 3 0 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 Fungal_trans_2 PF11951.8 KKK26659.1 - 1.5e-06 27.3 0.1 2.2e-06 26.7 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK26659.1 - 0.0013 18.8 0.8 0.0013 18.8 0.8 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ABC_tran PF00005.27 KKK26660.1 - 4.9e-47 159.9 0.3 3.5e-24 85.9 0.0 4.3 3 2 0 3 3 2 2 ABC transporter 4HB PF17947.1 KKK26660.1 - 1.5e-30 105.1 2.4 2.7e-30 104.2 0.8 2.4 2 0 0 2 2 1 1 Four helical bundle domain AAA_21 PF13304.6 KKK26660.1 - 1.5e-16 61.1 0.3 0.0024 17.8 0.0 5.1 6 0 0 6 6 5 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KKK26660.1 - 1.4e-15 57.3 0.0 9.3e-06 25.2 0.0 3.6 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KKK26660.1 - 1.9e-09 38.3 2.8 0.00054 20.5 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_29 PF13555.6 KKK26660.1 - 7e-08 32.1 0.1 0.01 15.6 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_28 PF13521.6 KKK26660.1 - 1.3e-07 32.0 0.0 0.017 15.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 KKK26660.1 - 1.4e-06 28.3 0.0 0.0013 18.6 0.0 2.6 2 0 0 2 2 2 1 RsgA GTPase PduV-EutP PF10662.9 KKK26660.1 - 1.5e-06 28.0 0.0 0.068 12.9 0.0 2.9 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.6 KKK26660.1 - 2.4e-06 28.0 0.0 0.083 13.3 0.0 3.7 2 1 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.23 KKK26660.1 - 3.7e-06 27.0 0.1 0.0056 16.7 0.0 3.4 4 0 0 4 4 2 1 50S ribosome-binding GTPase AAA_22 PF13401.6 KKK26660.1 - 5.4e-06 26.7 0.2 0.091 13.0 0.0 3.6 4 0 0 4 4 2 2 AAA domain AAA PF00004.29 KKK26660.1 - 1.1e-05 25.9 0.0 0.18 12.2 0.1 4.2 4 1 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 KKK26660.1 - 1.8e-05 25.3 0.1 0.39 11.3 0.0 3.1 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 KKK26660.1 - 0.00013 22.3 0.0 0.7 10.3 0.0 2.6 2 0 0 2 2 2 2 RNA helicase AAA_27 PF13514.6 KKK26660.1 - 0.00019 21.1 0.0 0.15 11.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KKK26660.1 - 0.00031 20.7 0.0 0.22 11.4 0.0 2.7 2 0 0 2 2 2 1 NACHT domain Dynamin_N PF00350.23 KKK26660.1 - 0.00032 20.8 0.0 0.002 18.2 0.0 2.4 2 0 0 2 2 2 1 Dynamin family AAA_15 PF13175.6 KKK26660.1 - 0.00032 20.5 2.3 0.77 9.4 0.1 3.5 3 2 0 3 3 2 2 AAA ATPase domain AAA_14 PF13173.6 KKK26660.1 - 0.00052 20.1 0.0 0.67 10.0 0.0 2.8 3 0 0 3 3 2 1 AAA domain AAA_24 PF13479.6 KKK26660.1 - 0.00052 19.8 0.0 1.6 8.4 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_33 PF13671.6 KKK26660.1 - 0.0007 19.8 0.0 0.82 9.8 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_13 PF13166.6 KKK26660.1 - 0.00091 18.0 0.0 0.23 10.0 0.0 3.0 3 0 0 3 3 3 1 AAA domain DUF87 PF01935.17 KKK26660.1 - 0.0011 19.1 2.6 0.15 12.1 0.0 3.3 4 0 0 4 4 2 1 Helicase HerA, central domain AAA_30 PF13604.6 KKK26660.1 - 0.0012 18.5 0.0 1.1 8.9 0.0 3.0 3 0 0 3 3 3 1 AAA domain HEAT_2 PF13646.6 KKK26660.1 - 0.0013 19.1 0.1 1.6 9.2 0.0 3.0 1 1 1 2 2 2 1 HEAT repeats G-alpha PF00503.20 KKK26660.1 - 0.0015 17.8 0.1 1.7 7.7 0.0 2.5 2 0 0 2 2 2 2 G-protein alpha subunit HEAT PF02985.22 KKK26660.1 - 0.002 18.2 1.8 8.4 7.0 0.0 5.3 5 0 0 5 5 4 0 HEAT repeat cobW PF02492.19 KKK26660.1 - 0.0023 17.5 0.1 1.5 8.3 0.0 3.2 4 0 0 4 4 3 1 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 KKK26660.1 - 0.0026 16.8 0.1 1.2 8.0 0.0 2.5 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB ATP_bind_1 PF03029.17 KKK26660.1 - 0.0051 16.6 0.1 3.7 7.3 0.0 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein ATPase_2 PF01637.18 KKK26660.1 - 0.0062 16.5 0.0 0.95 9.3 0.0 2.9 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea Roc PF08477.13 KKK26660.1 - 0.0068 16.6 0.0 5 7.4 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase NB-ARC PF00931.22 KKK26660.1 - 0.0081 15.4 0.1 0.22 10.7 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain MMS19_C PF12460.8 KKK26660.1 - 0.013 14.6 0.2 2.7 7.0 0.0 3.0 3 0 0 3 3 3 0 RNAPII transcription regulator C-terminal SbcCD_C PF13558.6 KKK26660.1 - 0.013 15.7 0.0 2.6 8.4 0.0 2.9 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_5 PF07728.14 KKK26660.1 - 0.013 15.5 0.0 13 5.7 0.0 3.5 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 KKK26660.1 - 0.02 14.3 0.1 3.6 6.9 0.0 3.2 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 KKK26660.1 - 0.02 14.4 0.1 3.6 7.1 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region T2SSE PF00437.20 KKK26660.1 - 0.021 13.9 0.1 7 5.6 0.0 3.1 3 0 0 3 3 3 0 Type II/IV secretion system protein CLP1_P PF16575.5 KKK26660.1 - 0.021 14.6 0.2 2.8 7.7 0.0 3.3 3 0 0 3 3 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop TsaE PF02367.17 KKK26660.1 - 0.023 14.7 0.0 5.5 7.0 0.0 2.7 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATP-synt_ab PF00006.25 KKK26660.1 - 0.034 13.8 0.0 2.8 7.5 0.0 2.6 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain IstB_IS21 PF01695.17 KKK26660.1 - 0.044 13.5 0.0 12 5.6 0.0 2.7 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_25 PF13481.6 KKK26660.1 - 0.046 13.3 0.0 3.9 7.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 KKK26660.1 - 0.057 13.3 0.0 1.2 9.0 0.0 2.3 2 0 0 2 2 2 0 Rad17 P-loop domain Septin PF00735.18 KKK26660.1 - 0.064 12.5 0.1 3.9 6.7 0.0 2.6 3 0 0 3 3 2 0 Septin Arf PF00025.21 KKK26660.1 - 0.1 12.0 0.0 14 5.1 0.0 2.6 2 0 0 2 2 2 0 ADP-ribosylation factor family NTPase_1 PF03266.15 KKK26660.1 - 0.11 12.4 0.2 17 5.3 0.1 2.7 2 0 0 2 2 2 0 NTPase AAA_19 PF13245.6 KKK26660.1 - 0.11 12.8 0.0 42 4.5 0.0 3.1 3 0 0 3 3 3 0 AAA domain dNK PF01712.19 KKK26660.1 - 0.14 12.0 0.0 2.6 7.8 0.0 2.3 2 0 0 2 2 2 0 Deoxynucleoside kinase RuvB_N PF05496.12 KKK26660.1 - 0.15 11.8 0.3 19 4.9 0.0 2.9 3 0 0 3 3 2 0 Holliday junction DNA helicase RuvB P-loop domain Med19 PF10278.9 KKK26660.1 - 1 9.3 7.5 1.2e+02 2.6 5.3 3.6 4 0 0 4 4 3 0 Mediator of RNA pol II transcription subunit 19 HEAT_EZ PF13513.6 KKK26660.1 - 5.8 7.5 7.0 68 4.1 0.0 4.7 3 2 2 5 5 4 0 HEAT-like repeat TPR_11 PF13414.6 KKK26661.1 - 1.3e-08 34.3 0.5 0.057 13.1 0.0 3.6 2 1 1 3 3 3 3 TPR repeat TPR_2 PF07719.17 KKK26661.1 - 3.4e-05 23.6 15.5 0.0037 17.3 0.0 6.4 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.28 KKK26661.1 - 9.8e-05 22.0 10.9 0.03 14.2 0.0 5.6 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.6 KKK26661.1 - 0.00065 19.9 0.1 0.24 11.8 0.1 3.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 KKK26661.1 - 0.01 16.0 1.3 10 6.6 0.0 4.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Plug_translocon PF10559.9 KKK26661.1 - 0.012 15.4 0.1 0.028 14.3 0.1 1.6 1 0 0 1 1 1 0 Plug domain of Sec61p TPR_7 PF13176.6 KKK26661.1 - 0.013 15.5 4.9 0.58 10.3 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 KKK26661.1 - 0.25 12.0 0.1 0.25 12.0 0.1 4.0 4 1 2 6 6 6 0 Tetratricopeptide repeat TPR_12 PF13424.6 KKK26661.1 - 0.53 10.6 9.0 1.3 9.4 0.7 4.4 3 2 1 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 KKK26661.1 - 1.3 9.6 16.4 0.26 11.8 1.6 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat Methyltransf_10 PF05971.12 KKK26662.1 - 2.1e-68 230.9 0.0 2.8e-68 230.5 0.0 1.1 1 0 0 1 1 1 1 RNA methyltransferase MTS PF05175.14 KKK26662.1 - 0.00042 19.9 0.0 0.00077 19.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain PLDc_2 PF13091.6 KKK26663.1 - 2e-14 53.6 0.0 4.2e-06 26.7 0.0 3.5 3 0 0 3 3 3 3 PLD-like domain PLDc PF00614.22 KKK26663.1 - 3.8e-14 52.2 2.8 3.9e-07 30.0 0.1 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif SWIRM PF04433.17 KKK26664.1 - 2.6e-32 111.0 0.1 5.7e-32 109.9 0.1 1.6 1 0 0 1 1 1 1 SWIRM domain SWIRM-assoc_1 PF16495.5 KKK26664.1 - 3.2e-31 107.1 11.6 8.5e-31 105.8 11.6 1.8 1 0 0 1 1 1 1 SWIRM-associated region 1 Myb_DNA-binding PF00249.31 KKK26664.1 - 2.7e-08 33.8 0.0 7.1e-08 32.5 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KKK26664.1 - 8.8e-07 29.1 0.0 2.3e-06 27.7 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Pkinase_fungal PF17667.1 KKK26664.1 - 0.13 11.0 2.0 0.23 10.2 2.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase ZZ PF00569.17 KKK26664.1 - 0.68 9.8 4.8 4.2 7.3 4.8 2.1 1 1 0 1 1 1 0 Zinc finger, ZZ type DUF4192 PF13830.6 KKK26664.1 - 1.1 9.2 9.7 2.4 8.1 9.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) CHCH PF06747.13 KKK26665.1 - 4.6e-08 33.0 4.8 8.2e-08 32.2 4.8 1.4 1 0 0 1 1 1 1 CHCH domain GCK PF07802.11 KKK26665.1 - 0.00092 19.6 1.2 0.0017 18.7 1.2 1.5 1 0 0 1 1 1 1 GCK domain DRY_EERY PF09750.9 KKK26666.1 - 0.069 13.4 0.3 0.13 12.5 0.3 1.4 1 0 0 1 1 1 0 Alternative splicing regulator MIF4G PF02854.19 KKK26667.1 - 6.1e-58 195.9 0.1 5.2e-33 114.5 0.0 3.8 4 0 0 4 4 4 2 MIF4G domain Upf2 PF04050.14 KKK26667.1 - 8.4e-42 143.1 10.2 8.4e-42 143.1 10.2 2.2 3 0 0 3 3 3 1 Up-frameshift suppressor 2 CENP-T_C PF15511.6 KKK26668.1 - 8e-09 35.6 0.1 9.7e-09 35.3 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 KKK26668.1 - 2.4e-05 24.7 0.1 2.8e-05 24.5 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.17 KKK26668.1 - 7.2e-05 22.9 0.1 0.0001 22.4 0.1 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 KKK26668.1 - 0.0002 21.6 0.1 0.00035 20.8 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 KKK26668.1 - 0.0004 20.7 0.1 0.00056 20.2 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 KKK26668.1 - 0.0085 16.2 0.0 0.01 15.9 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 KKK26668.1 - 0.031 14.3 0.0 0.037 14.0 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated UPF0137 PF03677.13 KKK26668.1 - 0.052 13.3 0.2 0.064 13.0 0.2 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) HIGH_NTase1_ass PF16581.5 KKK26668.1 - 0.11 12.5 0.0 0.12 12.3 0.0 1.1 1 0 0 1 1 1 0 Cytidyltransferase-related C-terminal region XRN_M PF17846.1 KKK26669.1 - 1.1e-149 499.2 2.8 1.2e-149 499.1 0.1 2.2 2 1 0 2 2 2 1 Xrn1 helical domain XRN_N PF03159.18 KKK26669.1 - 2.4e-101 338.2 0.4 2.4e-99 331.7 0.0 2.2 2 0 0 2 2 2 2 XRN 5'-3' exonuclease N-terminus zf-CCHC PF00098.23 KKK26669.1 - 0.085 13.0 2.3 0.15 12.2 2.3 1.4 1 0 0 1 1 1 0 Zinc knuckle EPSP_synthase PF00275.20 KKK26670.1 - 3.7e-127 424.5 0.0 5.5e-127 423.9 0.0 1.2 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.20 KKK26670.1 - 9.3e-99 329.8 0.1 2e-98 328.7 0.0 1.6 2 0 0 2 2 2 1 3-dehydroquinate synthase DHquinase_I PF01487.15 KKK26670.1 - 1.6e-58 198.6 0.0 3.7e-58 197.5 0.0 1.6 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.22 KKK26670.1 - 1.2e-38 132.7 0.1 6.5e-38 130.3 0.0 2.1 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.11 KKK26670.1 - 1.9e-24 85.7 0.0 5e-24 84.4 0.0 1.8 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain SDH_C PF18317.1 KKK26670.1 - 4.8e-08 32.6 0.3 1.8e-07 30.8 0.1 2.1 2 0 0 2 2 2 1 Shikimate 5'-dehydrogenase C-terminal domain Fe-ADH_2 PF13685.6 KKK26670.1 - 5.3e-07 29.6 0.0 1.3e-06 28.3 0.0 1.7 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Shikimate_DH PF01488.20 KKK26670.1 - 0.00067 19.7 0.0 0.0016 18.5 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Fe-ADH PF00465.19 KKK26670.1 - 0.0094 14.8 0.4 0.027 13.3 0.4 1.7 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase AAA_18 PF13238.6 KKK26670.1 - 0.013 16.0 0.0 0.036 14.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KKK26670.1 - 0.11 12.2 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain zf-C2H2 PF00096.26 KKK26671.1 - 2.7e-06 27.5 27.2 0.00015 22.0 1.4 4.9 5 0 0 5 5 5 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KKK26671.1 - 0.0047 17.6 22.4 0.028 15.2 1.1 5.2 5 0 0 5 5 5 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KKK26671.1 - 0.21 12.1 8.4 18 6.0 1.1 4.0 3 0 0 3 3 3 0 Zinc-finger double domain zf-BED PF02892.15 KKK26671.1 - 0.3 11.1 2.0 0.84 9.7 2.0 1.8 1 0 0 1 1 1 0 BED zinc finger zf-Di19 PF05605.12 KKK26671.1 - 0.42 10.9 5.8 0.9 9.9 1.5 2.5 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_11 PF16622.5 KKK26671.1 - 8 6.3 7.0 1.7 8.5 0.5 3.0 3 0 0 3 3 3 0 zinc-finger C2H2-type Sfi1 PF08457.10 KKK26672.1 - 7.4e-216 718.1 85.0 7.4e-216 718.1 85.0 2.1 1 1 1 2 2 2 2 Sfi1 spindle body protein NDUF_B7 PF05676.13 KKK26673.1 - 0.0011 18.7 1.4 0.51 10.1 0.4 2.1 1 1 1 2 2 2 2 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) CX9C PF16860.5 KKK26673.1 - 0.0018 18.3 0.8 0.0025 17.8 0.8 1.3 1 0 0 1 1 1 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Cmc1 PF08583.10 KKK26673.1 - 0.02 14.9 2.0 0.02 14.9 2.0 1.7 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.13 KKK26673.1 - 0.024 14.8 2.1 0.059 13.5 2.1 1.7 1 1 0 1 1 1 0 CHCH domain tRNA-synt_1 PF00133.22 KKK26674.1 - 2e-225 749.6 0.0 3.2e-225 749.0 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KKK26674.1 - 1.3e-26 93.4 0.0 3.7e-26 91.9 0.0 1.8 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 KKK26674.1 - 3.3e-14 52.5 0.1 5.4e-06 25.4 0.0 4.3 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 KKK26674.1 - 0.092 12.1 0.0 0.2 10.9 0.0 1.5 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain Uso1_p115_head PF04869.14 KKK26675.1 - 6.6e-109 363.8 0.0 1.3e-108 362.8 0.0 1.6 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, head region Uso1_p115_C PF04871.13 KKK26675.1 - 1.3e-17 64.4 34.2 1.3e-17 64.4 34.2 4.6 1 1 3 4 4 4 2 Uso1 / p115 like vesicle tethering protein, C terminal region Filament PF00038.21 KKK26675.1 - 0.00016 21.3 52.6 0.0011 18.6 16.1 2.8 1 1 1 2 2 2 2 Intermediate filament protein Lebercilin PF15619.6 KKK26675.1 - 0.0075 15.9 25.9 0.0075 15.9 25.9 3.5 1 1 2 3 3 3 1 Ciliary protein causing Leber congenital amaurosis disease Arm PF00514.23 KKK26675.1 - 0.087 12.9 1.0 24 5.1 0.0 4.1 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat DUF3584 PF12128.8 KKK26675.1 - 0.11 10.1 59.0 0.23 8.9 23.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) Nuc_N PF14448.6 KKK26675.1 - 0.12 12.3 1.1 0.34 10.8 0.2 2.3 2 0 0 2 2 2 0 Nuclease N terminal Cast PF10174.9 KKK26675.1 - 0.66 8.1 58.3 3.6 5.7 58.3 1.9 1 1 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone Golgin_A5 PF09787.9 KKK26675.1 - 1.3 8.4 56.6 0.091 12.2 8.3 3.5 1 1 2 3 3 3 0 Golgin subfamily A member 5 Rab5-bind PF09311.11 KKK26675.1 - 4.2 6.7 50.6 0.22 10.9 23.5 3.2 1 1 1 3 3 3 0 Rabaptin-like protein Baculo_PEP_C PF04513.12 KKK26675.1 - 5.5 7.0 17.2 5.9 6.9 4.1 4.5 2 1 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Histone PF00125.24 KKK26676.1 - 1e-51 174.7 2.5 1.1e-51 174.6 2.5 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 KKK26676.1 - 6e-06 26.6 0.0 9e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 KKK26676.1 - 4.9e-05 23.4 0.5 7.4e-05 22.8 0.1 1.5 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 KKK26676.1 - 6.5e-05 23.5 1.2 7.7e-05 23.3 1.2 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CBFD_NFYB_HMF PF00808.23 KKK26676.1 - 0.0032 17.7 0.3 0.0065 16.7 0.0 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 KKK26676.1 - 0.026 14.6 0.2 0.042 13.9 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit MFS_1 PF07690.16 KKK26677.1 - 1.2e-39 136.2 56.1 1.2e-39 136.2 56.1 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily Rav1p_C PF12234.8 KKK26678.1 - 9.8e-282 936.1 0.0 1.2e-281 935.8 0.0 1.1 1 0 0 1 1 1 1 RAVE protein 1 C terminal WD40 PF00400.32 KKK26678.1 - 4.7e-05 24.1 0.9 0.038 14.9 0.0 4.6 4 0 0 4 4 4 1 WD domain, G-beta repeat HAT_KAT11 PF08214.11 KKK26680.1 - 3.5e-109 365.3 0.0 6.7e-109 364.4 0.0 1.4 2 0 0 2 2 2 1 Histone acetylation protein Glyco_transf_21 PF13506.6 KKK26681.1 - 3.5e-14 52.7 0.0 1.6e-06 27.7 0.0 3.8 1 1 1 2 2 2 2 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.6 KKK26681.1 - 8.6e-07 29.1 0.0 2e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KKK26681.1 - 0.0017 18.2 0.0 0.022 14.6 0.0 2.4 2 1 0 2 2 2 1 Glycosyl transferase family 2 Ank_4 PF13637.6 KKK26682.1 - 1.4e-12 47.9 1.1 1.7e-06 28.4 0.3 2.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KKK26682.1 - 2.8e-12 47.0 0.3 1.5e-11 44.7 0.4 2.0 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 KKK26682.1 - 5.2e-10 39.3 0.8 2.3e-06 27.8 0.1 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 KKK26682.1 - 1.9e-09 37.0 0.2 5.8e-06 26.3 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 KKK26682.1 - 4e-08 33.4 0.5 2.4e-06 27.7 0.2 2.8 2 1 1 3 3 3 1 Ankyrin repeats (many copies) WW PF00397.26 KKK26683.1 - 5.2e-09 36.0 3.1 2.1e-08 34.1 3.1 2.1 1 0 0 1 1 1 1 WW domain Hydrophobin PF01185.18 KKK26684.1 - 2.4e-08 34.5 6.7 3.3e-08 34.1 6.7 1.2 1 0 0 1 1 1 1 Fungal hydrophobin NMO PF03060.15 KKK26685.1 - 1.3e-56 192.4 0.9 1.4e-55 189.0 0.9 1.9 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 KKK26685.1 - 2.3e-14 53.1 0.0 5.7e-07 28.8 0.0 2.1 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 KKK26685.1 - 0.0013 17.8 0.4 0.0026 16.9 0.4 1.5 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 KKK26685.1 - 0.049 12.8 0.6 0.13 11.3 0.6 1.8 1 1 0 1 1 1 0 Conserved region in glutamate synthase tRNA-synt_1e PF01406.19 KKK26686.1 - 1.6e-115 385.7 0.0 2.6e-115 385.0 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 KKK26686.1 - 4.1e-06 25.8 0.6 0.035 12.9 0.2 3.0 3 0 0 3 3 3 2 tRNA synthetases class I (M) 40S_SA_C PF16122.5 KKK26686.1 - 2.9 9.3 8.2 15 7.0 8.2 2.3 1 0 0 1 1 1 0 40S ribosomal protein SA C-terminus GCD14 PF08704.10 KKK26687.1 - 1.5e-59 201.6 0.9 1e-33 117.1 0.2 3.1 2 1 0 2 2 2 2 tRNA methyltransferase complex GCD14 subunit UBA PF00627.31 KKK26688.1 - 0.017 15.0 0.0 0.061 13.2 0.0 2.0 1 0 0 1 1 1 0 UBA/TS-N domain DnaJ PF00226.31 KKK26688.1 - 0.045 13.9 2.1 0.12 12.6 0.0 2.3 2 0 0 2 2 2 0 DnaJ domain TPR_12 PF13424.6 KKK26688.1 - 0.053 13.8 0.2 0.15 12.4 0.2 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TetR_C_1 PF02909.17 KKK26688.1 - 0.086 12.7 0.0 0.3 10.9 0.0 1.9 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain TPR_2 PF07719.17 KKK26688.1 - 0.12 12.5 5.4 0.04 14.0 1.2 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 KKK26688.1 - 4.3 8.1 9.3 0.29 11.8 1.5 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Cadherin_C_2 PF16492.5 KKK26689.1 - 0.075 13.8 0.2 0.28 11.9 0.2 2.0 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal adh_short_C2 PF13561.6 KKK26690.1 - 4.6e-55 186.7 0.3 1.1e-54 185.5 0.3 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KKK26690.1 - 2.3e-33 115.3 0.7 2.1e-32 112.2 0.7 2.0 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KKK26690.1 - 1.6e-07 31.4 0.2 4.7e-06 26.6 0.0 2.1 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 KKK26690.1 - 0.0029 17.1 0.4 0.013 15.0 0.0 1.9 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.19 KKK26690.1 - 0.019 14.3 0.0 0.033 13.5 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.16 KKK26690.1 - 0.091 12.4 0.1 0.13 11.9 0.1 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA eIF-6 PF01912.18 KKK26691.1 - 4.9e-46 156.6 0.1 5.4e-46 156.5 0.1 1.0 1 0 0 1 1 1 1 eIF-6 family DUF5349 PF17298.2 KKK26692.1 - 0.7 9.6 14.3 1.4 8.6 14.3 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5349) Voldacs PF03517.13 KKK26694.1 - 4.2e-25 88.5 1.8 7.4e-25 87.7 0.1 2.2 3 0 0 3 3 3 1 Regulator of volume decrease after cellular swelling Pyocin_S PF06958.12 KKK26694.1 - 0.74 10.4 5.5 1.7 9.2 5.5 1.6 1 0 0 1 1 1 0 S-type Pyocin Abhydrolase_2 PF02230.16 KKK26695.1 - 3.3e-08 33.6 0.0 6e-08 32.8 0.0 1.5 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 KKK26695.1 - 5.8e-06 27.1 2.9 7.8e-06 26.6 2.9 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KKK26695.1 - 0.038 13.3 0.0 0.71 9.1 0.0 2.4 3 0 0 3 3 3 0 Serine aminopeptidase, S33 Metallophos PF00149.28 KKK26696.1 - 5.2e-36 125.1 0.1 1e-35 124.1 0.1 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase MFS_1 PF07690.16 KKK26697.1 - 8e-25 87.5 18.7 1.8e-24 86.4 18.7 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Ion_trans_2 PF07885.16 KKK26698.1 - 3.9e-25 87.6 30.2 5.9e-15 55.0 7.9 3.5 3 1 0 3 3 3 2 Ion channel Ion_trans PF00520.31 KKK26698.1 - 0.00072 18.9 0.3 0.00072 18.9 0.3 3.6 2 1 0 3 3 3 2 Ion transport protein DUF1345 PF07077.11 KKK26698.1 - 0.033 13.9 2.5 2.9 7.5 0.0 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1345) Ribosomal_L19 PF01245.20 KKK26700.1 - 1e-15 57.6 0.4 1.9e-15 56.8 0.4 1.4 1 0 0 1 1 1 1 Ribosomal protein L19 MGTL PF17059.5 KKK26700.1 - 0.29 11.0 2.2 1.7 8.5 2.2 2.4 1 0 0 1 1 1 0 MgtA leader peptide RdRP PF05183.12 KKK26701.1 - 1e-133 447.1 0.0 1.4e-133 446.6 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase Opi1 PF08618.10 KKK26702.1 - 2.7e-44 152.1 20.5 1.8e-32 113.1 0.2 3.9 2 1 1 4 4 4 3 Transcription factor Opi1 NmrA PF05368.13 KKK26703.1 - 4e-29 101.8 0.0 4.9e-29 101.5 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KKK26703.1 - 5e-16 59.1 0.0 9.2e-16 58.3 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 KKK26703.1 - 9.7e-07 29.1 0.0 1.9e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 KKK26703.1 - 1.9e-05 25.1 0.0 5e-05 23.7 0.0 1.7 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 KKK26703.1 - 0.00062 19.8 0.2 0.0018 18.4 0.0 1.8 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.21 KKK26703.1 - 0.057 12.9 0.0 0.39 10.1 0.0 2.3 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family DapB_N PF01113.20 KKK26703.1 - 0.1 12.8 0.0 0.2 11.8 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus AA_permease PF00324.21 KKK26704.1 - 4.9e-78 262.8 30.2 6.2e-78 262.5 30.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KKK26704.1 - 1.1e-22 80.5 31.3 1.4e-22 80.1 31.3 1.1 1 0 0 1 1 1 1 Amino acid permease Hid1 PF12722.7 KKK26705.1 - 0 1106.9 0.0 0 1106.7 0.0 1.0 1 0 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.9 KKK26705.1 - 8.6e-107 358.1 0.0 1.1e-106 357.8 0.0 1.0 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein NPCC PF08058.11 KKK26705.1 - 2.4e-21 76.1 0.0 6.5e-21 74.7 0.0 1.8 1 0 0 1 1 1 1 Nuclear pore complex component DASH_Spc19 PF08287.11 KKK26705.1 - 0.0095 15.8 0.1 0.022 14.7 0.1 1.6 1 0 0 1 1 1 1 Spc19 BC10 PF06726.12 KKK26705.1 - 0.077 13.2 0.2 0.35 11.1 0.1 2.2 2 0 0 2 2 2 0 Bladder cancer-related protein BC10 AMP-binding PF00501.28 KKK26706.1 - 2.2e-06 26.5 0.1 9.2e-06 24.5 0.1 1.8 1 1 0 1 1 1 1 AMP-binding enzyme Ribosomal_S3Ae PF01015.18 KKK26707.1 - 3.5e-88 294.5 3.3 4.8e-88 294.0 3.3 1.2 1 0 0 1 1 1 1 Ribosomal S3Ae family SUI1 PF01253.22 KKK26707.1 - 0.0092 16.5 0.1 0.1 13.1 0.0 2.3 2 0 0 2 2 2 1 Translation initiation factor SUI1 Abhydro_lipase PF04083.16 KKK26707.1 - 0.14 11.7 0.0 0.29 10.7 0.0 1.5 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region NEMO PF11577.8 KKK26707.1 - 0.15 12.1 0.5 0.83 9.7 0.0 2.2 2 0 0 2 2 2 0 NF-kappa-B essential modulator NEMO UPRTase PF14681.6 KKK26708.1 - 1.5e-67 227.1 0.0 1.7e-67 226.9 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 KKK26708.1 - 0.0024 17.4 0.0 0.0034 16.9 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Flu_C_NS1 PF03506.13 KKK26708.1 - 0.21 11.6 0.3 0.35 10.8 0.3 1.3 1 0 0 1 1 1 0 Influenza C non-structural protein (NS1) DKCLD PF08068.12 KKK26709.1 - 3.5e-33 113.4 0.1 6.7e-32 109.3 0.1 2.5 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_C_2 PF16198.5 KKK26709.1 - 2.2e-23 82.2 0.7 3.8e-23 81.4 0.7 1.4 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain TruB_N PF01509.18 KKK26709.1 - 5.8e-23 81.9 0.2 1.9e-20 73.8 0.2 3.2 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) DER1 PF04511.15 KKK26709.1 - 2.4e-22 79.8 7.1 6.9e-19 68.5 7.1 2.2 1 1 0 1 1 1 1 Der1-like family PUA PF01472.20 KKK26709.1 - 4.6e-21 74.6 1.2 8.6e-21 73.7 1.2 1.5 1 0 0 1 1 1 1 PUA domain UPF0113 PF03657.13 KKK26709.1 - 0.0035 17.6 0.0 0.0083 16.4 0.0 1.6 1 0 0 1 1 1 1 UPF0113 PUA domain Rhomboid PF01694.22 KKK26709.1 - 0.076 13.0 4.7 0.49 10.4 4.7 2.0 1 1 0 1 1 1 0 Rhomboid family AP3D1 PF06375.11 KKK26709.1 - 0.28 11.4 20.7 0.44 10.8 20.7 1.3 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 Med19 PF10278.9 KKK26709.1 - 1 9.3 16.1 1.9 8.4 16.1 1.4 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 CLTH PF10607.9 KKK26710.1 - 1.7e-36 125.4 0.0 3.4e-36 124.3 0.0 1.5 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 KKK26710.1 - 0.14 12.2 0.0 0.39 10.7 0.0 1.9 1 0 0 1 1 1 0 LisH Snapin_Pallidin PF14712.6 KKK26710.1 - 0.21 12.0 4.7 0.82 10.1 1.5 2.6 2 0 0 2 2 2 0 Snapin/Pallidin DUF2431 PF10354.9 KKK26711.1 - 6.8e-64 215.2 0.0 3.5e-63 212.9 0.0 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF2431) TRAP_alpha PF03896.16 KKK26711.1 - 0.065 12.4 6.1 0.58 9.3 0.3 2.3 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit NOA36 PF06524.12 KKK26711.1 - 0.089 12.1 19.7 0.52 9.6 6.6 2.5 2 0 0 2 2 2 0 NOA36 protein Pex14_N PF04695.13 KKK26711.1 - 0.52 11.0 5.2 0.95 10.1 1.3 2.4 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region FAM176 PF14851.6 KKK26711.1 - 0.93 9.1 15.7 1.4 8.5 4.8 3.0 3 0 0 3 3 3 0 FAM176 family TLP-20 PF06088.11 KKK26711.1 - 1.1 9.1 14.0 0.86 9.5 0.3 3.0 3 0 0 3 3 3 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) dsrm PF00035.26 KKK26711.1 - 2.1 9.1 0.0 2.1 9.1 0.0 3.9 3 2 0 3 3 2 0 Double-stranded RNA binding motif GOLD_2 PF13897.6 KKK26711.1 - 3.4 8.2 15.4 2.6 8.5 1.8 3.3 3 0 0 3 3 3 0 Golgi-dynamics membrane-trafficking TFIIA PF03153.13 KKK26711.1 - 4.1 7.3 28.4 10 6.0 28.4 1.6 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RXT2_N PF08595.11 KKK26711.1 - 4.7 7.2 14.0 1.4 8.9 1.7 2.8 3 0 0 3 3 3 0 RXT2-like, N-terminal CPSF100_C PF13299.6 KKK26711.1 - 6 7.0 11.4 3.9 7.6 0.9 3.2 3 0 0 3 3 3 0 Cleavage and polyadenylation factor 2 C-terminal Pes-10 PF07149.11 KKK26711.1 - 6.5 5.7 9.3 2 7.4 0.4 2.1 2 0 0 2 2 2 0 Pes-10 DUF4746 PF15928.5 KKK26711.1 - 6.8 6.0 15.2 0.032 13.7 2.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4746) Sigma70_ner PF04546.13 KKK26711.1 - 7.4 6.4 17.7 1.3 8.8 1.9 2.9 3 0 0 3 3 3 0 Sigma-70, non-essential region EamA PF00892.20 KKK26712.1 - 1.3e-05 25.4 6.4 1.3e-05 25.4 6.4 2.3 2 0 0 2 2 2 1 EamA-like transporter family UPF0370 PF13980.6 KKK26712.1 - 0.16 12.0 0.0 0.6 10.2 0.0 2.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0370) PHO4 PF01384.20 KKK26712.1 - 1.4 7.9 14.6 0.32 10.0 6.4 2.3 1 1 0 2 2 2 0 Phosphate transporter family Thioredoxin PF00085.20 KKK26713.1 - 0.00014 21.8 0.0 0.00022 21.2 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin PGA2 PF07543.12 KKK26713.1 - 1.8 8.6 4.3 3.2 7.7 4.3 1.4 1 0 0 1 1 1 0 Protein trafficking PGA2 SMI1_KNR4 PF09346.10 KKK26714.1 - 1.4e-34 119.4 0.0 3.2e-34 118.2 0.0 1.7 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) SUKH_6 PF14568.6 KKK26714.1 - 0.072 13.5 0.0 1.1 9.7 0.0 2.3 1 1 0 1 1 1 0 SMI1-KNR4 cell-wall PNRC PF15365.6 KKK26715.1 - 2.5e-09 36.7 7.7 2.5e-09 36.7 7.7 2.4 2 0 0 2 2 2 1 Proline-rich nuclear receptor coactivator motif Med13_C PF06333.12 KKK26715.1 - 7.2 5.8 11.4 8.8 5.5 11.4 1.3 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain zf-rbx1 PF12678.7 KKK26716.1 - 3.6e-25 88.0 12.8 5.1e-25 87.5 12.8 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KKK26716.1 - 1.8e-17 63.1 10.5 2.4e-17 62.8 10.5 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 KKK26716.1 - 2.9e-06 27.5 15.0 0.00011 22.5 15.0 2.2 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KKK26716.1 - 9.6e-05 22.2 3.7 9.6e-05 22.2 3.7 2.4 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KKK26716.1 - 0.0014 18.5 11.9 0.026 14.4 11.9 2.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 KKK26716.1 - 0.17 12.1 9.1 0.8 9.9 9.2 1.9 1 1 1 2 2 2 0 FANCL C-terminal domain zf-C3HC4_3 PF13920.6 KKK26716.1 - 0.34 10.8 10.8 0.96 9.4 4.7 2.5 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KKK26716.1 - 0.43 10.6 7.8 1.6 8.8 7.8 2.0 1 1 0 1 1 1 0 RING-type zinc-finger Zn_ribbon_17 PF17120.5 KKK26716.1 - 0.59 9.8 14.7 0.11 12.2 4.6 2.3 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.5 KKK26716.1 - 1.1 9.0 17.3 1.1e+02 2.7 17.3 2.5 1 1 0 1 1 1 0 RING-like zinc finger GHMP_kinases_N PF00288.26 KKK26717.1 - 4.4e-10 39.6 0.0 1e-09 38.5 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KKK26717.1 - 0.00021 21.6 0.0 0.00044 20.6 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal CorA PF01544.18 KKK26718.1 - 1.1e-40 139.7 0.0 1.8e-40 139.1 0.0 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein 2-Hacid_dh_C PF02826.19 KKK26719.1 - 3.6e-52 176.3 0.0 5.5e-52 175.7 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KKK26719.1 - 1.8e-38 131.3 0.0 2.4e-38 130.8 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KKK26719.1 - 1.5e-05 25.2 0.1 4.5e-05 23.7 0.1 1.8 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase ACT PF01842.25 KKK26719.1 - 0.0002 21.0 0.1 0.00062 19.5 0.0 1.9 2 0 0 2 2 2 1 ACT domain AdoHcyase_NAD PF00670.21 KKK26719.1 - 0.001 19.1 0.0 0.003 17.6 0.0 1.7 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain IlvN PF07991.12 KKK26719.1 - 0.0083 15.7 0.1 0.29 10.7 0.0 2.3 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain XdhC_C PF13478.6 KKK26719.1 - 0.034 14.7 0.0 0.094 13.2 0.0 1.8 2 0 0 2 2 2 0 XdhC Rossmann domain 3HCDH_N PF02737.18 KKK26719.1 - 0.046 13.6 0.5 1.6 8.6 0.4 2.8 2 1 1 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain tRNA-synt_2b PF00587.25 KKK26720.1 - 1.9e-38 132.2 0.0 3.5e-38 131.4 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 KKK26720.1 - 8.1e-17 61.4 5.1 8.1e-17 61.4 5.1 1.9 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain Atg14 PF10186.9 KKK26720.1 - 3.2 6.8 6.3 1.9 7.5 4.6 1.4 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 NADH_B2 PF14813.6 KKK26721.1 - 0.0096 15.7 0.1 0.011 15.5 0.1 1.1 1 0 0 1 1 1 1 NADH dehydrogenase 1 beta subcomplex subunit 2 Pkinase PF00069.25 KKK26722.1 - 3.6e-62 210.1 0.0 4.3e-62 209.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK26722.1 - 4.8e-24 85.0 0.0 6.4e-24 84.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase P5-ATPase PF12409.8 KKK26723.1 - 2.8e-39 134.0 0.6 7.3e-39 132.7 0.4 1.9 2 0 0 2 2 2 1 P5-type ATPase cation transporter E1-E2_ATPase PF00122.20 KKK26723.1 - 7.4e-32 110.3 0.3 3.1e-31 108.3 0.0 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 KKK26723.1 - 1e-09 39.0 0.2 0.00022 21.6 0.0 3.2 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.21 KKK26723.1 - 1e-07 31.9 5.5 1e-07 31.9 5.5 2.3 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Cation_ATPase_N PF00690.26 KKK26723.1 - 0.0025 17.5 0.2 0.0097 15.6 0.0 2.0 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus AAA_18 PF13238.6 KKK26724.1 - 7.3e-24 84.8 0.3 1.2e-23 84.1 0.0 1.4 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 KKK26724.1 - 2.1e-07 31.4 0.0 5.4e-07 30.1 0.0 1.7 1 1 1 2 2 2 1 AAA domain AAA PF00004.29 KKK26724.1 - 0.00017 22.0 0.0 0.00029 21.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 KKK26724.1 - 0.0011 19.1 0.0 0.0039 17.4 0.0 1.8 1 1 0 2 2 2 1 AAA domain ADK PF00406.22 KKK26724.1 - 0.0026 17.9 0.0 0.0055 16.8 0.0 1.6 2 0 0 2 2 2 1 Adenylate kinase AAA_28 PF13521.6 KKK26724.1 - 0.0037 17.5 0.0 0.0048 17.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KKK26724.1 - 0.0038 17.5 0.1 0.0058 16.9 0.1 1.5 1 1 0 1 1 1 1 AAA domain Hydin_ADK PF17213.3 KKK26724.1 - 0.0053 17.1 0.0 0.0073 16.6 0.0 1.2 1 0 0 1 1 1 1 Hydin Adenylate kinase-like domain AAA_14 PF13173.6 KKK26724.1 - 0.013 15.6 0.0 0.023 14.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KKK26724.1 - 0.019 15.4 0.1 0.024 15.0 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain NTPase_1 PF03266.15 KKK26724.1 - 0.03 14.3 0.0 0.056 13.3 0.0 1.5 1 0 0 1 1 1 0 NTPase Cytidylate_kin2 PF13189.6 KKK26724.1 - 0.031 14.4 0.0 0.039 14.1 0.0 1.4 1 1 0 1 1 1 0 Cytidylate kinase-like family Viral_helicase1 PF01443.18 KKK26724.1 - 0.037 13.8 0.0 0.051 13.3 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase KTI12 PF08433.10 KKK26724.1 - 0.047 13.1 0.0 0.067 12.6 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Death PF00531.22 KKK26724.1 - 0.059 13.5 0.1 0.25 11.5 0.1 1.9 2 0 0 2 2 2 0 Death domain RNA_helicase PF00910.22 KKK26724.1 - 0.073 13.5 0.0 0.13 12.7 0.0 1.4 1 0 0 1 1 1 0 RNA helicase DUF2075 PF09848.9 KKK26724.1 - 0.086 12.1 0.0 0.13 11.4 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Ham1p_like PF01725.16 KKK26725.1 - 2.5e-60 203.6 0.0 2.7e-60 203.5 0.0 1.0 1 0 0 1 1 1 1 Ham1 family Ras PF00071.22 KKK26726.1 - 1.4e-38 132.0 0.6 1.8e-37 128.4 0.6 1.9 1 1 0 1 1 1 1 Ras family Roc PF08477.13 KKK26726.1 - 2.8e-14 53.4 0.1 7.9e-14 51.9 0.1 1.7 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKK26726.1 - 3.3e-05 23.4 0.0 0.0018 17.8 0.0 2.0 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KKK26726.1 - 9.1e-05 22.5 0.0 0.00012 22.2 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 KKK26726.1 - 0.0021 17.5 0.0 0.0071 15.8 0.0 1.7 1 1 1 2 2 2 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 KKK26726.1 - 0.0049 16.4 0.3 0.24 10.9 0.1 2.6 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_28 PF13521.6 KKK26726.1 - 0.012 15.8 0.0 0.02 15.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KKK26726.1 - 0.016 15.2 0.0 0.02 14.9 0.0 1.5 1 1 0 1 1 1 0 AAA domain FeoB_N PF02421.18 KKK26726.1 - 0.07 12.7 0.0 1.2 8.6 0.0 2.0 2 0 0 2 2 2 0 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KKK26726.1 - 0.15 12.0 0.0 11 5.9 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase NAGLU_N PF12971.7 KKK26726.1 - 0.16 11.8 0.1 0.41 10.4 0.1 1.7 1 0 0 1 1 1 0 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain TniB PF05621.11 KKK26726.1 - 0.18 11.2 0.0 0.35 10.2 0.0 1.5 2 0 0 2 2 2 0 Bacterial TniB protein WAPL PF07814.13 KKK26727.1 - 2.5e-70 237.1 0.0 4e-70 236.5 0.0 1.3 1 0 0 1 1 1 1 Wings apart-like protein regulation of heterochromatin Wap1 PF16997.5 KKK26727.1 - 0.096 11.8 0.0 1.5 7.9 0.1 2.4 2 0 0 2 2 2 0 Wap1 domain Myosin_head PF00063.21 KKK26728.1 - 2.1e-264 878.9 2.8 3e-264 878.4 2.8 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) NAP PF00956.18 KKK26728.1 - 3.8e-96 321.4 9.2 3.8e-96 321.4 9.2 2.6 2 0 0 2 2 1 1 Nucleosome assembly protein (NAP) DIL PF01843.19 KKK26728.1 - 4.3e-26 91.2 2.6 4.3e-26 91.2 2.6 2.6 2 1 1 3 3 3 1 DIL domain IQ PF00612.27 KKK26728.1 - 1.7e-12 45.9 33.9 4.4e-05 22.9 0.2 6.8 6 0 0 6 6 6 4 IQ calmodulin-binding motif CENP-B_dimeris PF09026.10 KKK26728.1 - 2.9e-06 27.6 21.6 0.00015 22.1 7.8 3.0 2 0 0 2 2 2 2 Centromere protein B dimerisation domain KASH_CCD PF14662.6 KKK26728.1 - 0.00046 20.1 11.7 0.00046 20.1 11.7 2.9 1 1 0 2 2 2 1 Coiled-coil region of CCDC155 or KASH AAA_22 PF13401.6 KKK26728.1 - 0.0013 19.0 2.7 0.0091 16.3 0.0 3.0 2 0 0 2 2 2 1 AAA domain GAS PF13851.6 KKK26728.1 - 0.024 14.0 41.1 0.0059 16.0 16.4 3.5 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding AAA_16 PF13191.6 KKK26728.1 - 0.043 14.2 0.0 0.043 14.2 0.0 2.8 3 0 0 3 3 2 0 AAA ATPase domain DUF3450 PF11932.8 KKK26728.1 - 0.05 12.9 32.0 0.042 13.2 15.4 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) RNA_helicase PF00910.22 KKK26728.1 - 0.15 12.4 0.0 0.99 9.8 0.0 2.4 2 0 0 2 2 2 0 RNA helicase ATG16 PF08614.11 KKK26728.1 - 0.19 11.9 37.5 4.1 7.6 21.3 3.2 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Spc7 PF08317.11 KKK26728.1 - 0.25 10.2 30.4 1.4 7.7 30.4 2.2 1 1 0 1 1 1 0 Spc7 kinetochore protein Imm68 PF15583.6 KKK26728.1 - 0.36 11.0 3.9 1.1 9.4 3.9 1.9 1 0 0 1 1 1 0 Immunity protein 68 Myosin_N PF02736.19 KKK26728.1 - 0.65 9.9 3.5 0.38 10.6 0.7 2.2 2 0 0 2 2 2 0 Myosin N-terminal SH3-like domain Atg14 PF10186.9 KKK26728.1 - 0.77 8.8 32.2 0.27 10.3 12.2 2.8 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 FlaC_arch PF05377.11 KKK26728.1 - 2.3 8.7 12.6 0.58 10.6 0.7 4.2 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) Flagellin_N PF00669.20 KKK26728.1 - 2.8 8.1 9.7 2.9 8.0 7.8 1.9 1 1 0 1 1 1 0 Bacterial flagellin N-terminal helical region FUSC PF04632.12 KKK26728.1 - 7.3 5.0 9.6 13 4.2 9.6 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family Es2 PF09751.9 KKK26730.1 - 2.1e-138 462.7 4.8 2.8e-138 462.3 4.8 1.1 1 0 0 1 1 1 1 Nuclear protein Es2 Mid1 PF12929.7 KKK26731.1 - 3.1e-107 359.4 21.0 6.4e-63 213.4 13.2 2.9 1 1 1 2 2 2 2 Stretch-activated Ca2+-permeable channel component Fz PF01392.22 KKK26731.1 - 0.03 15.0 6.2 0.099 13.3 4.5 2.6 2 1 0 2 2 2 0 Fz domain AA_kinase PF00696.28 KKK26732.1 - 1.5e-42 145.8 0.3 2.3e-42 145.2 0.3 1.3 1 0 0 1 1 1 1 Amino acid kinase family ACT_7 PF13840.6 KKK26732.1 - 8.2e-12 44.7 0.8 1.3e-09 37.7 0.1 2.7 2 0 0 2 2 2 2 ACT domain ACT PF01842.25 KKK26732.1 - 3.6e-11 42.6 0.3 2.2e-08 33.7 0.1 3.0 2 1 0 2 2 2 2 ACT domain Peptidase_C78 PF07910.13 KKK26733.1 - 1.2e-70 237.3 0.0 1.5e-70 237.0 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C78 Hist_deacetyl PF00850.19 KKK26733.1 - 0.0025 17.4 0.0 0.0036 16.8 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain SseB_C PF14581.6 KKK26733.1 - 0.06 13.4 0.0 0.18 11.9 0.0 1.8 1 0 0 1 1 1 0 SseB protein C-terminal domain Ribosomal_L23eN PF03939.13 KKK26734.1 - 2.9e-27 94.6 8.9 6.1e-27 93.6 8.9 1.6 1 0 0 1 1 1 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.20 KKK26734.1 - 1.8e-15 57.0 1.4 3.2e-15 56.2 1.4 1.5 1 0 0 1 1 1 1 Ribosomal protein L23 zf-Tim10_DDP PF02953.15 KKK26735.1 - 1.5e-22 79.0 2.4 2e-22 78.6 2.4 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger G10 PF01125.17 KKK26736.1 - 2.8e-43 147.2 0.5 3.4e-43 146.9 0.5 1.0 1 0 0 1 1 1 1 G10 protein Forkhead PF00250.18 KKK26737.1 - 8.2e-36 122.1 0.1 1.5e-35 121.3 0.1 1.4 1 0 0 1 1 1 1 Forkhead domain PDT PF00800.18 KKK26738.1 - 1.2e-63 214.3 0.1 2e-63 213.5 0.1 1.4 1 0 0 1 1 1 1 Prephenate dehydratase ACT PF01842.25 KKK26738.1 - 0.015 15.1 0.0 0.035 13.9 0.0 1.7 1 0 0 1 1 1 0 ACT domain eRF1_2 PF03464.15 KKK26739.1 - 2.1e-47 160.7 0.1 3.4e-47 160.1 0.1 1.3 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 KKK26739.1 - 1.8e-39 134.7 0.5 3.7e-39 133.7 0.5 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.15 KKK26739.1 - 4.3e-21 75.2 0.0 7.2e-21 74.5 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 baeRF_family10 PF18854.1 KKK26739.1 - 4.6e-10 39.9 0.0 8.4e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 acVLRF1 PF18859.1 KKK26739.1 - 2.7e-07 30.9 0.0 4.4e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor Ribosomal_L7Ae PF01248.26 KKK26739.1 - 0.11 12.2 0.0 0.27 11.0 0.0 1.6 1 0 0 1 1 1 0 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DUF3440 PF11922.8 KKK26739.1 - 0.12 12.0 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3440) Rad50_zn_hook PF04423.14 KKK26739.1 - 0.15 11.9 0.1 21 5.0 0.0 3.1 2 0 0 2 2 2 0 Rad50 zinc hook motif Aa_trans PF01490.18 KKK26740.1 - 2.2e-70 237.5 18.8 2.6e-70 237.2 18.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 KKK26740.1 - 3e-05 23.3 4.3 3e-05 23.3 4.3 2.1 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family MerC PF03203.14 KKK26740.1 - 0.0039 17.6 0.8 0.0039 17.6 0.8 3.3 2 1 0 2 2 2 1 MerC mercury resistance protein Bmt2 PF11968.8 KKK26741.1 - 1.5e-57 195.0 0.0 2e-57 194.6 0.0 1.1 1 0 0 1 1 1 1 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 Methyltransf_23 PF13489.6 KKK26741.1 - 0.00023 21.0 0.0 0.00031 20.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain TPR_17 PF13431.6 KKK26742.1 - 0.012 16.0 0.0 0.46 11.0 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 KKK26742.1 - 0.069 12.8 0.1 0.87 9.3 0.0 2.7 3 0 0 3 3 3 0 TPR repeat Glyoxalase PF00903.25 KKK26743.1 - 9.9e-21 74.3 0.3 1.7e-15 57.3 0.0 2.4 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 KKK26743.1 - 4.2e-13 49.5 0.1 1.1e-05 25.7 0.0 2.6 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 KKK26743.1 - 2.9e-05 24.3 0.1 0.53 10.4 0.1 3.3 3 1 0 3 3 3 2 Glyoxalase-like domain Glyoxalase_5 PF14696.6 KKK26743.1 - 0.00012 22.3 0.0 0.0039 17.4 0.0 2.3 1 1 0 1 1 1 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal DUF4844 PF16133.5 KKK26743.1 - 0.067 13.7 0.1 0.3 11.6 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4844) FAA_hydrolase PF01557.18 KKK26744.1 - 9e-52 175.9 0.0 1.2e-51 175.5 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.11 KKK26744.1 - 6.8e-31 106.6 0.0 1.2e-30 105.8 0.0 1.4 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal HgmA PF04209.13 KKK26745.1 - 6e-211 700.6 0.1 6.8e-211 700.4 0.1 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase p450 PF00067.22 KKK26746.1 - 4.7e-72 243.2 0.0 5.3e-72 243.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Gcn1_N PF12074.8 KKK26746.1 - 0.19 11.0 0.0 0.53 9.5 0.0 1.7 1 1 0 1 1 1 0 Generalcontrol nonderepressible 1 (Gcn1) N-terminal zinc_ribbon_15 PF17032.5 KKK26748.1 - 0.00084 20.0 0.1 0.13 13.1 0.0 2.3 2 0 0 2 2 2 1 zinc-ribbon family zf-DNA_Pol PF08996.10 KKK26748.1 - 0.031 14.0 3.0 3.4 7.4 0.3 2.2 2 0 0 2 2 2 0 DNA Polymerase alpha zinc finger hnRNP_Q_AcD PF18360.1 KKK26748.1 - 0.14 12.1 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 Heterogeneous nuclear ribonucleoprotein Q acidic domain DZR PF12773.7 KKK26748.1 - 0.15 12.1 7.7 2.1 8.4 1.0 2.6 2 1 0 2 2 2 0 Double zinc ribbon CENP-B_dimeris PF09026.10 KKK26748.1 - 0.16 12.4 0.2 0.31 11.5 0.2 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain C1_1 PF00130.22 KKK26748.1 - 0.38 10.7 3.8 4.2 7.3 0.3 2.8 2 1 1 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) IKI3 PF04762.12 KKK26749.1 - 0 1031.3 0.0 0 1031.1 0.0 1.0 1 0 0 1 1 1 1 IKI3 family COX7C PF02935.16 KKK26749.1 - 2.6e-17 62.8 6.0 5.9e-17 61.7 6.0 1.6 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc BTAD PF03704.17 KKK26749.1 - 0.041 14.3 1.2 0.079 13.4 1.2 1.4 1 0 0 1 1 1 0 Bacterial transcriptional activator domain Gmad1 PF10647.9 KKK26749.1 - 0.053 13.3 0.0 16 5.2 0.0 2.7 2 0 0 2 2 2 0 Lipoprotein LpqB beta-propeller domain Coatomer_WDAD PF04053.14 KKK26749.1 - 0.12 11.4 0.0 5.9 5.8 0.0 2.4 2 0 0 2 2 2 0 Coatomer WD associated region rRNA_proc-arch PF13234.6 KKK26750.1 - 5.1e-90 302.1 1.0 1.1e-89 301.0 0.0 2.1 3 0 0 3 3 3 1 rRNA-processing arch domain DSHCT PF08148.12 KKK26750.1 - 8.5e-55 184.9 4.5 3.6e-54 182.8 3.3 2.3 2 0 0 2 2 2 1 DSHCT (NUC185) domain DEAD PF00270.29 KKK26750.1 - 4.9e-18 65.5 0.2 2.5e-17 63.2 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KKK26750.1 - 3.7e-06 27.3 0.0 1.2e-05 25.6 0.0 1.9 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KKK26750.1 - 7.7e-05 22.8 0.0 0.0002 21.4 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit T2SSE PF00437.20 KKK26750.1 - 0.014 14.5 0.0 0.063 12.3 0.0 2.0 2 0 0 2 2 2 0 Type II/IV secretion system protein Prp19 PF08606.11 KKK26750.1 - 0.026 14.5 0.4 1.4 8.9 0.2 2.8 2 0 0 2 2 2 0 Prp19/Pso4-like ATPase_2 PF01637.18 KKK26750.1 - 0.073 13.0 0.1 0.26 11.2 0.0 2.0 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_22 PF13401.6 KKK26750.1 - 0.095 13.0 0.0 0.41 10.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUF5388 PF17363.2 KKK26750.1 - 0.28 11.4 1.2 1.1 9.5 0.1 2.5 3 0 0 3 3 3 0 Family of unknown function (DUF5388) Cut8 PF08559.10 KKK26751.1 - 1.6e-79 267.0 0.0 1.9e-79 266.7 0.0 1.0 1 0 0 1 1 1 1 Cut8, nuclear proteasome tether protein bVLRF1 PF18826.1 KKK26752.1 - 5.4e-66 221.1 0.3 1.2e-65 219.9 0.3 1.7 1 0 0 1 1 1 1 bacteroidetes VLRF1 release factor Ank_5 PF13857.6 KKK26752.1 - 0.00016 21.9 0.0 0.00038 20.7 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Neogenin_C PF06583.12 KKK26752.1 - 0.00044 20.2 0.8 0.00044 20.2 0.8 2.2 2 0 0 2 2 2 1 Neogenin C-terminus Pkinase PF00069.25 KKK26752.1 - 0.00081 18.8 0.4 0.0023 17.3 0.1 1.9 1 1 1 2 2 2 1 Protein kinase domain Ank PF00023.30 KKK26752.1 - 0.0038 17.6 0.4 0.012 16.0 0.4 1.8 1 0 0 1 1 1 1 Ankyrin repeat zf-C2H2_2 PF12756.7 KKK26752.1 - 0.024 15.0 1.2 0.042 14.2 0.3 1.8 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 KKK26752.1 - 0.15 12.4 1.4 0.32 11.3 1.4 1.6 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding ABC_membrane PF00664.23 KKK26753.1 - 3.8e-79 266.2 30.8 6.2e-45 154.0 12.3 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KKK26753.1 - 1.1e-51 175.0 0.0 2.8e-30 105.6 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KKK26753.1 - 2.4e-09 37.0 3.8 0.0042 16.5 0.2 4.2 2 2 0 4 4 4 3 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 KKK26753.1 - 7.6e-06 26.0 0.4 0.21 11.7 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KKK26753.1 - 4.1e-05 23.6 0.0 0.015 15.2 0.0 2.6 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 KKK26753.1 - 7.7e-05 23.1 0.3 0.014 15.8 0.2 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 KKK26753.1 - 0.00024 20.8 0.2 0.6 9.9 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 KKK26753.1 - 0.00059 19.7 1.5 0.34 10.7 0.0 3.5 2 1 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system Dynamin_N PF00350.23 KKK26753.1 - 0.00098 19.2 0.3 0.19 11.8 0.0 2.8 2 0 0 2 2 2 1 Dynamin family AAA_30 PF13604.6 KKK26753.1 - 0.0019 18.0 1.1 0.22 11.2 0.0 3.1 2 1 0 2 2 2 1 AAA domain AAA_23 PF13476.6 KKK26753.1 - 0.005 17.4 1.3 0.33 11.4 0.0 2.8 3 0 0 3 3 2 1 AAA domain 60KD_IMP PF02096.20 KKK26753.1 - 0.011 15.7 6.1 0.041 13.8 6.1 2.0 1 0 0 1 1 1 0 60Kd inner membrane protein AAA_15 PF13175.6 KKK26753.1 - 0.018 14.7 0.3 0.52 10.0 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain DUF87 PF01935.17 KKK26753.1 - 0.053 13.6 0.4 1.4 8.9 0.0 2.6 2 0 0 2 2 2 0 Helicase HerA, central domain Roc PF08477.13 KKK26753.1 - 0.077 13.2 0.4 39 4.5 0.0 3.5 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase IstB_IS21 PF01695.17 KKK26753.1 - 0.73 9.5 2.5 6.5 6.4 0.0 3.2 4 0 0 4 4 4 0 IstB-like ATP binding protein AAA_22 PF13401.6 KKK26753.1 - 3.1 8.1 5.3 36 4.6 0.1 3.6 4 0 0 4 4 3 0 AAA domain NACHT PF05729.12 KKK26753.1 - 6.6 6.6 5.4 2.7 7.9 0.1 2.7 3 0 0 3 3 3 0 NACHT domain Glyco_hydro_15 PF00723.21 KKK26755.1 - 9.1e-102 341.1 3.7 6.1e-97 325.2 0.3 2.6 3 0 0 3 3 3 2 Glycosyl hydrolases family 15 CBM_20 PF00686.19 KKK26755.1 - 5.8e-33 112.7 0.1 1.6e-32 111.2 0.1 1.8 1 0 0 1 1 1 1 Starch binding domain CTP_transf_1 PF01148.20 KKK26756.1 - 4.8e-74 249.5 18.1 5.7e-74 249.2 18.1 1.0 1 0 0 1 1 1 1 Cytidylyltransferase family Cyclin_N PF00134.23 KKK26757.1 - 2.2e-09 37.1 0.1 1.9e-07 30.9 0.0 2.4 1 1 1 2 2 2 2 Cyclin, N-terminal domain RPA43_OB PF17875.1 KKK26757.1 - 0.31 11.7 1.3 0.58 10.8 1.3 1.4 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I S4 PF01479.25 KKK26758.1 - 4.3e-15 55.2 0.0 8.1e-15 54.3 0.0 1.5 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.6 KKK26758.1 - 0.065 13.1 0.0 0.21 11.4 0.0 1.8 2 0 0 2 2 2 0 S4 domain RNA_pol_Rpc4 PF05132.14 KKK26758.1 - 0.31 11.5 11.8 0.18 12.2 0.6 2.3 2 0 0 2 2 2 0 RNA polymerase III RPC4 DUF722 PF05263.11 KKK26758.1 - 0.82 9.9 4.0 1.2 9.3 1.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF722) CPSF100_C PF13299.6 KKK26758.1 - 2.1 8.5 12.2 0.16 12.1 1.4 2.3 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal DUF3636 PF12331.8 KKK26759.1 - 1.3e-55 187.3 0.0 2.4e-55 186.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3636) LCD1 PF09798.9 KKK26759.1 - 3.1e-05 22.7 2.7 0.14 10.7 0.1 3.1 2 1 1 3 3 3 3 DNA damage checkpoint protein Nup54_57_C PF18570.1 KKK26759.1 - 0.0025 17.4 0.0 0.0063 16.1 0.0 1.6 1 0 0 1 1 1 1 NUP57/Nup54 C-terminal domain TFIIA PF03153.13 KKK26760.1 - 1.9 8.4 31.3 0.16 12.0 19.9 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit SelP_N PF04592.14 KKK26760.1 - 2.5 7.4 33.4 0.089 12.2 25.5 2.1 2 0 0 2 2 2 0 Selenoprotein P, N terminal region WD40 PF00400.32 KKK26761.1 - 2.4e-28 97.8 6.6 1.3e-06 29.0 0.0 6.9 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKK26761.1 - 1.9e-13 50.5 0.0 0.00038 20.7 0.0 4.8 3 2 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KKK26761.1 - 0.00054 19.9 0.1 0.31 10.9 0.0 2.9 2 1 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Cornichon PF03311.14 KKK26762.1 - 4.3e-50 169.1 13.0 4.9e-50 168.9 13.0 1.0 1 0 0 1 1 1 1 Cornichon protein 3Beta_HSD PF01073.19 KKK26763.1 - 2.7e-53 180.8 0.0 3.4e-53 180.5 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KKK26763.1 - 4.3e-37 127.9 0.0 5.4e-37 127.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KKK26763.1 - 8.8e-20 71.4 0.0 1.8e-19 70.3 0.0 1.5 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 KKK26763.1 - 5.8e-17 61.7 0.0 7.8e-17 61.3 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 KKK26763.1 - 9.3e-12 44.6 0.0 2e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.15 KKK26763.1 - 3.3e-09 36.3 0.0 4.1e-08 32.7 0.1 2.4 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 KKK26763.1 - 3e-08 33.7 0.0 4.3e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding adh_short_C2 PF13561.6 KKK26763.1 - 0.00047 19.8 0.0 0.001 18.7 0.0 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KKK26763.1 - 0.00051 19.5 0.0 0.00097 18.6 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KKK26763.1 - 0.00073 19.5 0.2 0.0087 16.0 0.2 2.1 1 1 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 KKK26763.1 - 0.0014 18.9 0.0 0.0033 17.7 0.0 1.6 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NmrA PF05368.13 KKK26763.1 - 0.026 14.1 0.0 0.041 13.4 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family AAA_lid_8 PF17868.1 KKK26764.1 - 0.22 11.5 2.0 15 5.6 0.1 2.6 2 0 0 2 2 2 0 AAA lid domain FAD_binding_3 PF01494.19 KKK26765.1 - 2.9e-16 59.7 0.0 7.3e-16 58.3 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KKK26765.1 - 0.00015 21.1 0.0 0.00026 20.4 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KKK26765.1 - 0.001 19.5 0.0 0.003 18.1 0.0 1.8 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KKK26765.1 - 0.0012 18.5 0.2 0.0027 17.4 0.2 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KKK26765.1 - 0.0023 18.1 0.0 0.0051 17.0 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KKK26765.1 - 0.0048 15.6 0.1 0.0075 15.0 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein AlaDh_PNT_C PF01262.21 KKK26765.1 - 0.014 14.7 0.0 0.021 14.1 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.7 KKK26765.1 - 0.037 13.4 3.1 0.13 11.6 0.6 2.3 3 0 0 3 3 3 0 FAD dependent oxidoreductase SE PF08491.10 KKK26765.1 - 0.039 13.0 0.0 0.053 12.6 0.0 1.2 1 0 0 1 1 1 0 Squalene epoxidase GIDA PF01134.22 KKK26765.1 - 0.068 12.2 0.1 0.12 11.5 0.1 1.5 1 1 0 1 1 1 0 Glucose inhibited division protein A FAD_binding_2 PF00890.24 KKK26765.1 - 0.09 11.8 0.2 0.24 10.4 0.1 1.7 2 0 0 2 2 2 0 FAD binding domain F-box-like PF12937.7 KKK26766.1 - 0.0018 18.1 1.0 0.0041 17.0 1.0 1.6 1 0 0 1 1 1 1 F-box-like Fungal_trans PF04082.18 KKK26767.1 - 1.6e-05 24.1 0.0 3.1e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_25 PF01183.20 KKK26768.1 - 2.3e-34 119.1 0.0 3e-34 118.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 25 Peptidase_M24 PF00557.24 KKK26769.1 - 1.3e-47 162.2 0.0 1.8e-47 161.7 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 MFS_1 PF07690.16 KKK26769.1 - 1.4e-43 149.2 44.5 2.8e-43 148.2 44.5 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily zf-C6H2 PF15801.5 KKK26769.1 - 4.2e-20 71.8 6.2 8.9e-20 70.7 6.2 1.6 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding Sugar_tr PF00083.24 KKK26769.1 - 9.1e-14 51.2 9.3 9.1e-14 51.2 9.3 2.8 3 0 0 3 3 3 2 Sugar (and other) transporter zf-MYND PF01753.18 KKK26769.1 - 0.0008 19.4 4.7 0.0008 19.4 4.7 1.9 2 0 0 2 2 2 1 MYND finger EF-hand_1 PF00036.32 KKK26770.1 - 9.3e-14 49.9 2.5 2.4e-06 26.7 0.2 3.4 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 KKK26770.1 - 6.8e-13 48.9 8.1 1.3e-08 35.2 1.1 2.8 2 1 2 4 4 4 3 EF-hand domain pair ZZ PF00569.17 KKK26770.1 - 4.7e-12 45.5 4.2 8.1e-12 44.8 4.2 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type EF-hand_6 PF13405.6 KKK26770.1 - 2e-10 39.7 2.2 0.00018 21.1 0.1 3.0 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 KKK26770.1 - 1.3e-06 28.2 2.8 0.029 14.2 0.3 3.2 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 KKK26770.1 - 5.9e-06 25.5 4.1 0.0039 16.6 0.2 3.1 3 0 0 3 3 3 2 EF hand C1_2 PF03107.16 KKK26770.1 - 0.0073 16.6 4.0 0.013 15.8 4.0 1.4 1 0 0 1 1 1 1 C1 domain dCMP_cyt_deam_1 PF00383.23 KKK26771.1 - 2.8e-05 23.9 0.0 0.033 14.0 0.1 2.3 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region Cyclin PF08613.11 KKK26772.1 - 2.8e-32 112.3 2.0 1.1e-31 110.3 2.0 2.0 1 1 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 KKK26772.1 - 0.00014 21.6 0.0 0.00023 20.9 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain BC10 PF06726.12 KKK26773.1 - 1.2e-15 57.5 9.9 2.4e-15 56.5 9.9 1.5 1 0 0 1 1 1 1 Bladder cancer-related protein BC10 Ge1_WD40 PF16529.5 KKK26774.1 - 0.0083 15.1 0.0 0.028 13.4 0.0 1.7 1 1 0 1 1 1 1 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF4193 PF13834.6 KKK26774.1 - 0.067 13.7 1.6 0.21 12.1 0.8 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4193) DUF2884 PF11101.8 KKK26774.1 - 0.27 10.7 12.1 0.053 13.0 3.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2884) GlutR_dimer PF00745.20 KKK26774.1 - 5.3 7.6 5.8 1.4 9.4 0.9 2.5 2 0 0 2 2 2 0 Glutamyl-tRNAGlu reductase, dimerisation domain CorA PF01544.18 KKK26775.1 - 1.3e-10 41.1 0.9 1.3e-09 37.8 0.0 2.1 1 1 1 2 2 2 1 CorA-like Mg2+ transporter protein CK2S PF15011.6 KKK26775.1 - 0.23 11.3 1.4 22 4.9 0.0 2.6 2 1 0 2 2 2 0 Casein Kinase 2 substrate Chs7 PF12271.8 KKK26776.1 - 1.1e-110 369.5 5.2 1.3e-110 369.4 5.2 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone DUF4149 PF13664.6 KKK26776.1 - 0.063 13.6 1.0 0.063 13.6 1.0 3.0 3 1 0 3 3 3 0 Domain of unknown function (DUF4149) Gemini_mov PF01708.16 KKK26776.1 - 4.4 7.1 9.1 7.6 6.4 0.1 3.3 3 0 0 3 3 3 0 Geminivirus putative movement protein DLH PF01738.18 KKK26777.1 - 4.4e-29 101.6 0.0 5e-29 101.4 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family BAAT_C PF08840.11 KKK26777.1 - 0.00015 21.7 0.0 0.2 11.6 0.0 2.1 1 1 1 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S15 PF02129.18 KKK26777.1 - 0.0064 16.1 0.0 0.0081 15.8 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) LIDHydrolase PF10230.9 KKK26777.1 - 0.01 15.4 0.0 0.014 15.0 0.0 1.1 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Peptidase_S9 PF00326.21 KKK26777.1 - 0.031 13.8 0.0 0.18 11.3 0.0 1.9 1 1 1 2 2 2 0 Prolyl oligopeptidase family FSH1 PF03959.13 KKK26777.1 - 0.08 12.6 0.0 0.16 11.6 0.0 1.6 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Arm PF00514.23 KKK26779.1 - 4.1e-17 61.6 0.6 0.001 19.1 0.0 8.2 8 0 0 8 8 8 4 Armadillo/beta-catenin-like repeat HEAT PF02985.22 KKK26779.1 - 2.8e-05 24.0 6.7 6.3 7.3 0.0 7.1 7 0 0 7 7 7 2 HEAT repeat HEAT_2 PF13646.6 KKK26779.1 - 0.004 17.5 0.3 3.5 8.1 0.0 4.4 4 1 0 4 4 4 1 HEAT repeats DUF1494 PF07379.11 KKK26779.1 - 0.17 11.8 0.1 0.42 10.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1494) HEAT_EZ PF13513.6 KKK26779.1 - 2.9 8.5 4.6 30 5.2 0.0 4.5 6 0 0 6 6 6 0 HEAT-like repeat Aldo_ket_red PF00248.21 KKK26780.1 - 4.2e-61 206.7 0.0 4.7e-61 206.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family ERG4_ERG24 PF01222.17 KKK26781.1 - 3.6e-139 464.3 20.2 4.5e-139 463.9 20.2 1.1 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family zf-C3HC4 PF00097.25 KKK26781.1 - 3.2e-07 30.1 7.2 6.7e-07 29.1 7.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KKK26781.1 - 1.5e-06 28.0 5.0 3.6e-06 26.7 5.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KKK26781.1 - 2.2e-06 27.4 4.8 2.4e-05 24.1 1.8 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KKK26781.1 - 4.7e-06 26.5 6.3 4.8e-06 26.5 3.3 2.4 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 KKK26781.1 - 6.6e-06 26.4 7.9 4.5e-05 23.7 8.0 2.3 1 1 1 2 2 2 1 Ring finger domain zf-C3HC4_4 PF15227.6 KKK26781.1 - 2.3e-05 24.4 5.5 0.00011 22.2 5.9 2.0 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 KKK26781.1 - 2.9e-05 23.9 4.3 8e-05 22.5 4.3 1.8 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KKK26781.1 - 0.097 12.6 8.4 0.53 10.2 8.2 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-Nse PF11789.8 KKK26781.1 - 0.37 10.7 3.7 0.76 9.7 3.7 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-rbx1 PF12678.7 KKK26781.1 - 0.89 9.9 4.3 2.9 8.2 4.3 1.9 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_10 PF16685.5 KKK26781.1 - 1.4 9.1 3.6 3.1 8.0 3.6 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 UCH PF00443.29 KKK26782.1 - 3.8e-46 157.7 0.0 5.7e-46 157.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KKK26782.1 - 1.1e-09 38.3 0.0 3.5e-05 23.5 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase APH PF01636.23 KKK26783.1 - 1.6e-08 34.7 0.2 4.7e-08 33.3 0.2 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family AMP-binding PF00501.28 KKK26784.1 - 2.9e-63 213.9 0.0 9.7e-63 212.2 0.0 1.7 2 0 0 2 2 2 1 AMP-binding enzyme AMP-binding_C PF13193.6 KKK26784.1 - 2.5e-06 28.3 0.0 5.2e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Autoind_bind PF03472.15 KKK26784.1 - 0.071 12.6 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 Autoinducer binding domain Aminotran_1_2 PF00155.21 KKK26785.1 - 4e-42 144.7 0.0 4.9e-42 144.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KKK26785.1 - 6.3e-09 35.3 0.0 1.1e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 KKK26785.1 - 7.2e-07 28.1 0.0 1e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 KKK26785.1 - 0.00072 18.9 0.0 0.0011 18.3 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Alliinase_C PF04864.13 KKK26785.1 - 0.13 11.1 0.0 0.24 10.3 0.0 1.3 1 1 0 1 1 1 0 Allinase ABC2_membrane PF01061.24 KKK26786.1 - 2.5e-38 131.6 20.6 4.7e-38 130.7 20.6 1.5 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 KKK26786.1 - 4.9e-25 88.6 0.0 9e-25 87.8 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KKK26786.1 - 3.6e-05 23.7 0.0 0.3 10.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 KKK26786.1 - 0.00022 20.4 16.3 0.00022 20.4 16.3 2.2 1 1 0 2 2 2 1 ABC-2 family transporter protein AAA_16 PF13191.6 KKK26786.1 - 0.0085 16.5 0.0 0.018 15.4 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 KKK26786.1 - 0.0094 15.7 0.1 0.021 14.6 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KKK26786.1 - 0.011 15.7 0.0 0.019 14.8 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_18 PF13238.6 KKK26786.1 - 0.022 15.3 0.0 0.054 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KKK26786.1 - 0.022 15.0 0.0 0.055 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 KKK26786.1 - 0.05 14.1 0.0 0.14 12.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KKK26786.1 - 0.073 13.0 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_33 PF13671.6 KKK26786.1 - 0.084 13.0 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.19 KKK26786.1 - 0.096 12.1 0.0 2.1 7.7 0.0 2.2 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain ATPase_2 PF01637.18 KKK26786.1 - 0.1 12.5 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_14 PF13173.6 KKK26786.1 - 0.12 12.4 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KKK26786.1 - 0.17 11.4 1.0 0.32 10.5 0.1 1.9 2 0 0 2 2 2 0 AAA domain Spem1 PF15670.5 KKK26786.1 - 0.41 10.2 4.2 0.69 9.4 4.2 1.2 1 0 0 1 1 1 0 Spermatid maturation protein 1 Laminin_EGF PF00053.24 KKK26786.1 - 1.2 9.4 28.7 0.6 10.3 7.9 3.7 2 1 1 3 3 3 0 Laminin EGF domain Na_H_Exchanger PF00999.21 KKK26787.1 - 5.5e-47 160.4 19.3 7e-47 160.0 19.3 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family RNase_H PF00075.24 KKK26788.1 - 1.4e-37 129.1 0.0 2.2e-37 128.4 0.0 1.2 1 0 0 1 1 1 1 RNase H Cauli_VI PF01693.16 KKK26788.1 - 2.8e-37 126.7 15.2 4.2e-19 68.6 1.8 2.4 2 0 0 2 2 2 2 Caulimovirus viroplasmin RVT_3 PF13456.6 KKK26788.1 - 0.014 15.2 0.0 0.026 14.3 0.0 1.6 1 0 0 1 1 1 0 Reverse transcriptase-like Ank_5 PF13857.6 KKK26789.1 - 0.0019 18.5 0.1 3.5 8.1 0.0 2.7 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 KKK26789.1 - 0.011 16.3 0.1 11 6.8 0.0 3.1 3 0 0 3 3 3 0 Ankyrin repeats (many copies) Ank_2 PF12796.7 KKK26789.1 - 0.048 14.3 0.0 0.34 11.5 0.0 2.0 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) Fox-1_C PF12414.8 KKK26789.1 - 0.11 12.9 0.0 0.21 12.0 0.0 1.4 1 0 0 1 1 1 0 Calcitonin gene-related peptide regulator C terminal Ank_3 PF13606.6 KKK26789.1 - 0.2 12.3 1.1 71 4.5 0.0 3.5 4 0 0 4 4 4 0 Ankyrin repeat APH PF01636.23 KKK26790.1 - 2.8e-06 27.5 0.0 3.8e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KKK26790.1 - 3.8e-05 23.4 0.0 7.2e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.20 KKK26790.1 - 0.0024 17.2 0.0 0.006 15.9 0.0 1.6 2 0 0 2 2 2 1 Ecdysteroid kinase DUF1679 PF07914.11 KKK26790.1 - 0.013 14.4 0.0 0.019 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Ribosomal_S8 PF00410.19 KKK26791.1 - 6.3e-14 52.0 0.0 9e-13 48.3 0.0 2.2 1 1 0 1 1 1 1 Ribosomal protein S8 DUF1769 PF08588.10 KKK26793.1 - 2.6e-26 91.6 0.2 4.8e-26 90.7 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) AAA_13 PF13166.6 KKK26794.1 - 0.0014 17.4 0.2 0.0014 17.4 0.2 3.2 2 1 1 3 3 3 1 AAA domain Myosin_tail_1 PF01576.19 KKK26794.1 - 0.0035 15.3 41.6 0.026 12.4 2.1 3.4 3 0 0 3 3 3 3 Myosin tail Sec3_C_2 PF15278.6 KKK26794.1 - 0.0086 16.4 0.3 0.046 14.1 0.1 2.3 2 0 0 2 2 2 1 Sec3 exocyst complex subunit Fib_alpha PF08702.10 KKK26794.1 - 0.13 12.4 17.5 0.14 12.4 5.4 4.4 3 1 1 4 4 4 0 Fibrinogen alpha/beta chain family ADIP PF11559.8 KKK26794.1 - 6 6.9 39.2 0.19 11.8 0.2 4.5 2 1 2 5 5 5 0 Afadin- and alpha -actinin-Binding Iso_dh PF00180.20 KKK26796.1 - 3.3e-96 322.5 0.0 9.4e-96 321.0 0.0 1.6 1 1 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF1447 PF07288.11 KKK26796.1 - 0.12 12.4 0.1 0.33 11.0 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1447) DUF3506 PF12014.8 KKK26797.1 - 5e-53 178.8 0.0 8.5e-53 178.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3506) F-box-like PF12937.7 KKK26797.1 - 4.1e-11 42.6 0.7 8.9e-11 41.5 0.7 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KKK26797.1 - 6.7e-08 32.2 0.1 7.7e-07 28.8 0.1 2.3 2 0 0 2 2 2 1 F-box domain Pyrid_ox_like PF16242.5 KKK26797.1 - 0.092 12.3 0.0 0.54 9.8 0.0 2.2 3 0 0 3 3 3 0 Pyridoxamine 5'-phosphate oxidase like F-box_4 PF15966.5 KKK26797.1 - 0.72 9.8 2.3 0.44 10.5 0.1 1.7 2 0 0 2 2 2 0 F-box VRR_NUC PF08774.11 KKK26798.1 - 5e-24 84.5 0.0 2.5e-23 82.2 0.0 2.2 1 0 0 1 1 1 1 VRR-NUC domain Ribosomal_S13_N PF08069.12 KKK26799.1 - 4.7e-29 100.2 0.1 7.7e-29 99.5 0.1 1.4 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 KKK26799.1 - 4.9e-15 55.5 0.3 7.1e-15 55.0 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein S15 PAX PF00292.18 KKK26799.1 - 0.021 14.7 0.1 0.051 13.5 0.0 1.7 2 0 0 2 2 2 0 'Paired box' domain YflT PF11181.8 KKK26799.1 - 0.11 13.0 0.0 0.16 12.5 0.0 1.3 1 0 0 1 1 1 0 Heat induced stress protein YflT Dpy-30 PF05186.13 KKK26800.1 - 7.5e-13 48.0 0.0 9.3e-13 47.6 0.0 1.1 1 0 0 1 1 1 1 Dpy-30 motif PP1_bind PF15276.6 KKK26800.1 - 0.026 14.8 0.5 0.06 13.7 0.2 2.0 1 1 1 2 2 2 0 Protein phosphatase 1 binding Mito_carr PF00153.27 KKK26801.1 - 3.2e-60 200.1 4.8 1.2e-18 66.8 0.0 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein TPK_catalytic PF04263.16 KKK26803.1 - 5.9e-34 116.7 0.0 4.8e-31 107.3 0.0 2.2 1 1 1 2 2 2 2 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.14 KKK26803.1 - 3.3e-19 68.4 0.0 5.6e-19 67.6 0.0 1.4 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain YL1 PF05764.13 KKK26804.1 - 0.0011 19.2 2.7 0.0012 19.0 2.7 1.1 1 0 0 1 1 1 1 YL1 nuclear protein AAA PF00004.29 KKK26805.1 - 2.6e-11 44.1 0.0 6.4e-11 42.8 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KKK26805.1 - 1.3e-07 32.0 0.0 3e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.15 KKK26805.1 - 8.3e-06 25.8 0.0 3.8e-05 23.7 0.0 2.0 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_33 PF13671.6 KKK26805.1 - 5.3e-05 23.4 0.0 0.00013 22.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KKK26805.1 - 7.2e-05 22.8 0.0 0.00016 21.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KKK26805.1 - 9.2e-05 22.2 0.0 0.00016 21.4 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain RsgA_GTPase PF03193.16 KKK26805.1 - 0.0084 16.0 0.0 0.016 15.1 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 KKK26805.1 - 0.013 15.9 0.0 0.06 13.7 0.0 2.1 1 1 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.6 KKK26805.1 - 0.036 13.7 0.0 0.79 9.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KKK26805.1 - 0.045 14.3 0.0 0.11 13.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KKK26805.1 - 0.086 12.9 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KKK26805.1 - 0.11 12.3 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.21 KKK26805.1 - 0.12 11.8 0.1 1.1 8.6 0.0 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 KKK26805.1 - 0.16 11.7 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 KKK26805.1 - 0.19 10.9 0.0 0.43 9.7 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain Ribosomal_L1 PF00687.21 KKK26806.1 - 1.3e-61 208.0 7.5 1.9e-61 207.4 5.0 2.1 2 0 0 2 2 2 1 Ribosomal protein L1p/L10e family ETF PF01012.21 KKK26806.1 - 9e-43 146.3 5.5 2.3e-42 144.9 5.5 1.7 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ETF_alpha PF00766.19 KKK26806.1 - 4.9e-32 109.8 0.6 1.5e-31 108.3 0.2 2.1 2 0 0 2 2 2 1 Electron transfer flavoprotein FAD-binding domain SUN PF03856.13 KKK26807.1 - 1.7e-92 309.3 12.6 3.5e-92 308.3 12.6 1.5 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) FSA_C PF10479.9 KKK26807.1 - 0.06 11.5 20.9 0.089 10.9 20.9 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus PRCC PF10253.9 KKK26807.1 - 0.19 12.5 3.8 0.27 12.0 3.8 1.3 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting RIFIN PF02009.16 KKK26807.1 - 3 7.7 5.7 4 7.2 5.7 1.2 1 0 0 1 1 1 0 Rifin UPF0121 PF03661.13 KKK26808.1 - 5.6e-23 81.6 7.6 3.2e-19 69.3 1.2 2.0 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0121) Septin PF00735.18 KKK26809.1 - 1.7e-121 404.8 0.1 1.7e-121 404.8 0.1 1.6 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 KKK26809.1 - 2.4e-08 34.0 0.7 4.2e-08 33.3 0.0 1.7 2 0 0 2 2 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KKK26809.1 - 1.9e-05 24.3 1.7 0.0016 18.0 0.0 2.9 2 2 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KKK26809.1 - 0.00011 22.1 3.0 0.002 18.1 0.9 3.1 2 1 0 2 2 2 1 RsgA GTPase ABC_tran PF00005.27 KKK26809.1 - 0.00013 22.5 2.7 0.02 15.4 0.0 3.0 2 1 0 3 3 3 1 ABC transporter AIG1 PF04548.16 KKK26809.1 - 0.00093 18.6 1.7 0.0023 17.3 0.0 2.2 2 0 0 2 2 2 1 AIG1 family AAA_16 PF13191.6 KKK26809.1 - 0.0016 18.8 0.2 0.0051 17.2 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain Roc PF08477.13 KKK26809.1 - 0.0022 18.2 0.0 0.0048 17.1 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_22 PF13401.6 KKK26809.1 - 0.0038 17.5 0.6 0.017 15.4 0.0 2.4 2 2 1 3 3 3 1 AAA domain Ras PF00071.22 KKK26809.1 - 0.0043 16.7 0.1 0.032 13.8 0.0 2.4 2 0 0 2 2 2 1 Ras family AAA_29 PF13555.6 KKK26809.1 - 0.014 15.1 0.0 0.026 14.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Dynamin_N PF00350.23 KKK26809.1 - 0.039 14.0 6.7 0.85 9.6 0.0 3.8 4 1 0 4 4 3 0 Dynamin family AAA_24 PF13479.6 KKK26809.1 - 0.043 13.5 0.0 0.1 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KKK26809.1 - 0.054 13.9 0.8 0.77 10.2 0.0 2.5 2 0 0 2 2 2 0 RNA helicase FtsK_SpoIIIE PF01580.18 KKK26809.1 - 0.058 12.7 0.0 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family Sigma54_activat PF00158.26 KKK26809.1 - 0.093 12.4 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_7 PF12775.7 KKK26809.1 - 0.098 12.2 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Exonuc_VII_L PF02601.15 KKK26809.1 - 0.14 11.7 5.0 0.24 11.0 5.0 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit ATP_bind_1 PF03029.17 KKK26809.1 - 0.22 11.3 5.3 1.6 8.5 0.0 3.1 3 1 0 3 3 3 0 Conserved hypothetical ATP binding protein TSNAXIP1_N PF15739.5 KKK26809.1 - 2.4 8.6 14.2 2.8 8.3 0.0 2.8 2 1 1 3 3 2 0 Translin-associated factor X-interacting N-terminus DUF3987 PF13148.6 KKK26809.1 - 7.3 5.5 9.4 1.9 7.4 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) RRM_1 PF00076.22 KKK26810.1 - 2.4e-27 94.5 0.0 5.6e-11 42.1 0.0 3.7 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KKK26810.1 - 0.0038 17.0 0.0 2.4 8.1 0.0 3.2 3 0 0 3 3 3 2 Occluded RNA-recognition motif 7tm_2 PF00002.24 KKK26811.1 - 2.8e-06 26.8 22.0 8.5e-06 25.2 16.5 2.0 1 1 0 2 2 2 2 7 transmembrane receptor (Secretin family) Dicty_CAR PF05462.11 KKK26811.1 - 0.018 14.2 19.7 0.062 12.4 10.4 2.7 2 1 0 2 2 2 0 Slime mold cyclic AMP receptor DUF212 PF02681.14 KKK26811.1 - 3.6 7.7 5.7 1.7 8.8 2.2 2.0 2 0 0 2 2 2 0 Divergent PAP2 family FMO-like PF00743.19 KKK26812.1 - 1.7e-13 49.9 0.0 1.4e-12 46.8 0.0 2.4 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KKK26812.1 - 2.6e-11 43.3 0.0 5.5e-06 25.8 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KKK26812.1 - 2.4e-09 36.9 0.0 2.5e-05 23.7 0.0 3.1 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KKK26812.1 - 4e-09 36.1 0.1 2.8e-05 23.4 0.0 3.2 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KKK26812.1 - 4.7e-09 36.4 0.0 1.1e-08 35.2 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KKK26812.1 - 6.9e-06 25.9 0.0 0.12 12.0 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KKK26812.1 - 0.00022 21.2 0.0 1 9.3 0.0 2.7 2 0 0 2 2 2 2 FAD-NAD(P)-binding Thi4 PF01946.17 KKK26812.1 - 0.0036 16.6 0.1 0.049 12.9 0.0 2.2 2 0 0 2 2 2 1 Thi4 family GIDA PF01134.22 KKK26812.1 - 0.017 14.2 0.0 0.42 9.6 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_binding_2 PF00890.24 KKK26812.1 - 0.063 12.4 0.0 2.5 7.1 0.0 2.5 2 0 0 2 2 2 0 FAD binding domain DUF2914 PF11141.8 KKK26812.1 - 0.083 12.7 0.0 0.2 11.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2914) HI0933_like PF03486.14 KKK26812.1 - 0.18 10.4 0.0 13 4.3 0.0 2.2 2 0 0 2 2 2 0 HI0933-like protein OGG_N PF07934.12 KKK26813.1 - 4e-37 127.0 0.0 8.3e-37 126.0 0.0 1.5 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.25 KKK26813.1 - 2.4e-17 63.3 0.0 4.7e-17 62.4 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 KKK26813.1 - 0.03 14.2 0.0 0.066 13.1 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif Rax2 PF12768.7 KKK26814.1 - 3.8e-73 245.5 0.8 2.4e-70 236.3 0.0 3.7 3 0 0 3 3 3 1 Cortical protein marker for cell polarity Reg_prop PF07494.11 KKK26814.1 - 0.13 12.5 0.2 8.4 7.0 0.0 4.1 3 0 0 3 3 3 0 Two component regulator propeller PRIMA1 PF16101.5 KKK26814.1 - 0.2 11.7 0.0 0.43 10.6 0.0 1.5 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 DUF5122 PF17164.4 KKK26814.1 - 0.8 10.0 17.7 4.8 7.6 0.1 6.4 6 0 0 6 6 6 0 Domain of unknown function (DUF5122) beta-propeller Fungal_trans_2 PF11951.8 KKK26815.1 - 2e-11 43.4 0.0 7.9e-11 41.4 0.0 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK26815.1 - 2.6e-07 30.6 12.6 4.5e-07 29.9 12.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CheD PF03975.13 KKK26815.1 - 0.099 12.7 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 CheD chemotactic sensory transduction POB3_N PF17292.2 KKK26816.1 - 2.1e-31 108.2 0.1 6.3e-30 103.4 0.0 2.9 3 0 0 3 3 3 1 POB3-like N-terminal PH domain SSrecog PF03531.14 KKK26816.1 - 3.1e-30 103.9 0.3 3.5e-29 100.5 0.0 2.9 4 0 0 4 4 4 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.12 KKK26816.1 - 4.3e-27 94.3 0.0 6.1e-26 90.7 0.0 2.5 3 0 0 3 3 3 1 Histone chaperone Rttp106-like PH_TFIIH PF08567.11 KKK26816.1 - 0.0084 16.4 0.0 0.96 9.8 0.0 3.3 4 0 0 4 4 4 1 TFIIH p62 subunit, N-terminal domain CDC45 PF02724.14 KKK26816.1 - 7.3 4.7 12.4 11 4.1 12.4 1.3 1 0 0 1 1 1 0 CDC45-like protein Asp PF00026.23 KKK26817.1 - 9.7e-29 100.8 0.3 1.3e-28 100.4 0.3 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KKK26817.1 - 0.00026 21.3 4.4 0.0017 18.6 2.5 2.7 1 1 1 2 2 2 1 Xylanase inhibitor N-terminal Glyco_hydro_16 PF00722.21 KKK26818.1 - 4.9e-42 143.4 4.0 8.2e-42 142.7 4.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 DAHP_synth_2 PF01474.16 KKK26819.1 - 9.8e-145 482.4 0.0 1.1e-144 482.2 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family Ribosomal_L15e PF00827.17 KKK26820.1 - 7.7e-07 29.0 0.3 7.8e-07 29.0 0.3 1.0 1 0 0 1 1 1 1 Ribosomal L15 PfkB PF00294.24 KKK26821.1 - 1.5e-18 67.1 0.0 1.9e-18 66.8 0.0 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase HSDR_N_2 PF13588.6 KKK26821.1 - 0.039 14.0 0.0 0.056 13.4 0.0 1.3 1 0 0 1 1 1 0 Type I restriction enzyme R protein N terminus (HSDR_N) Tau95 PF09734.9 KKK26822.1 - 1.4e-44 152.3 0.3 2.5e-44 151.5 0.3 1.5 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain Tau95_N PF17682.1 KKK26822.1 - 2.8e-37 127.7 0.0 4.7e-37 127.0 0.0 1.4 1 0 0 1 1 1 1 Tau95 Triple barrel domain Cwf_Cwc_15 PF04889.12 KKK26822.1 - 0.37 10.5 7.3 0.54 10.0 7.3 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein adh_short PF00106.25 KKK26824.1 - 1.8e-31 109.1 0.0 1.1e-23 83.8 0.0 2.0 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KKK26824.1 - 9.2e-17 61.4 0.0 5.5e-13 49.0 0.0 2.0 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KKK26824.1 - 7.9e-09 35.7 0.0 1.2e-08 35.1 0.0 1.1 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KKK26824.1 - 0.14 11.3 0.0 0.21 10.7 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein GMC_oxred_N PF00732.19 KKK26825.1 - 5.6e-60 203.2 0.0 6.9e-60 202.9 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KKK26825.1 - 2.1e-29 102.9 0.0 3.8e-29 102.0 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KKK26825.1 - 6.3e-06 25.5 0.5 0.042 12.9 0.3 2.1 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 KKK26825.1 - 0.0021 17.2 0.3 0.0036 16.4 0.3 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 KKK26825.1 - 0.0046 17.2 0.2 0.016 15.4 0.2 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KKK26825.1 - 0.0062 16.2 1.9 0.047 13.3 0.8 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 KKK26825.1 - 0.014 14.7 0.1 0.024 13.9 0.1 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.6 KKK26825.1 - 0.046 13.0 0.2 1 8.6 0.3 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KKK26825.1 - 0.16 11.2 0.0 0.52 9.5 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_DMAT PF11991.8 KKK26826.1 - 0.00034 20.1 0.1 0.00046 19.7 0.1 1.1 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase RPA43_OB PF17875.1 KKK26827.1 - 5.3e-41 140.1 7.2 1.5e-40 138.6 0.0 3.0 2 1 0 2 2 2 1 RPA43 OB domain in RNA Pol I SHS2_Rpb7-N PF03876.17 KKK26827.1 - 1.7e-07 31.5 0.0 3.3e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 Dicty_REP PF05086.12 KKK26827.1 - 0.0031 15.6 1.5 0.0031 15.6 1.5 2.0 2 0 0 2 2 2 1 Dictyostelium (Slime Mold) REP protein Mucin PF01456.17 KKK26827.1 - 0.0097 15.9 7.0 0.0097 15.9 7.0 2.5 2 0 0 2 2 2 1 Mucin-like glycoprotein Tim54 PF11711.8 KKK26827.1 - 0.04 12.7 5.7 0.17 10.6 1.3 2.1 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 Ctr PF04145.15 KKK26827.1 - 0.087 13.4 1.1 21 5.7 0.0 2.3 2 0 0 2 2 2 0 Ctr copper transporter family DUF3439 PF11921.8 KKK26827.1 - 1.2 9.1 13.8 0.41 10.6 7.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) AJAP1_PANP_C PF15298.6 KKK26827.1 - 2.5 8.3 12.2 0.11 12.7 5.4 2.0 2 0 0 2 2 2 0 AJAP1/PANP C-terminus CPSF100_C PF13299.6 KKK26827.1 - 3.4 7.8 12.9 20 5.3 0.1 2.6 3 0 0 3 3 3 0 Cleavage and polyadenylation factor 2 C-terminal Zip PF02535.22 KKK26827.1 - 5.1 6.2 6.5 0.4 9.9 1.2 1.7 2 0 0 2 2 2 0 ZIP Zinc transporter HNF-1_N PF04814.13 KKK26827.1 - 5.8 7.5 14.9 0.3 11.7 1.5 2.2 2 0 0 2 2 2 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus DUF4834 PF16118.5 KKK26827.1 - 5.8 7.9 8.8 5.8 7.9 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) NPR3 PF03666.13 KKK26827.1 - 6.8 5.4 15.2 1.2 7.9 7.6 2.0 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF4050 PF13259.6 KKK26827.1 - 7 6.9 13.0 12 6.2 6.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4050) NST1 PF13945.6 KKK26827.1 - 8.9 6.4 16.5 15 5.6 10.2 2.2 2 0 0 2 2 2 0 Salt tolerance down-regulator Pyr_redox_2 PF07992.14 KKK26828.1 - 1.7e-41 142.3 0.0 2.7e-41 141.7 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.26 KKK26828.1 - 1.4e-15 57.0 0.1 3e-15 55.9 0.1 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pyr_redox PF00070.27 KKK26828.1 - 4.5e-09 36.7 0.0 2.1e-07 31.4 0.0 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Rieske_2 PF13806.6 KKK26828.1 - 2.9e-05 23.9 0.0 9.3e-05 22.3 0.0 1.9 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Reductase_C PF14759.6 KKK26828.1 - 4.9e-05 23.8 0.0 0.00024 21.6 0.0 2.2 2 0 0 2 2 2 1 Reductase C-terminal NAD_binding_9 PF13454.6 KKK26828.1 - 0.029 14.3 1.3 13 5.7 0.0 3.2 3 0 0 3 3 3 0 FAD-NAD(P)-binding DUF1188 PF06690.11 KKK26828.1 - 0.032 13.8 0.1 0.076 12.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1188) DUF834 PF05754.14 KKK26828.1 - 1.1 9.3 3.5 6.5 6.9 0.1 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF834) F-box-like PF12937.7 KKK26829.1 - 0.0056 16.6 0.2 0.015 15.2 0.2 1.7 1 0 0 1 1 1 1 F-box-like Arrestin_N PF00339.29 KKK26830.1 - 3e-14 53.3 0.2 2.6e-12 47.0 0.1 3.0 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Rgp1 PF08737.10 KKK26830.1 - 0.076 12.2 0.0 0.13 11.4 0.0 1.4 1 0 0 1 1 1 0 Rgp1 Bul1_C PF04426.12 KKK26830.1 - 0.082 12.3 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 Bul1 C terminus Zn_clus PF00172.18 KKK26832.1 - 0.00032 20.8 2.8 0.00032 20.8 2.8 2.4 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KKK26832.1 - 0.00093 18.1 0.0 0.0014 17.5 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain PDEase_I PF00233.19 KKK26832.1 - 0.14 11.9 0.1 1.6 8.4 0.0 2.1 2 0 0 2 2 2 0 3'5'-cyclic nucleotide phosphodiesterase UCH_1 PF13423.6 KKK26832.1 - 0.35 10.4 1.1 0.6 9.6 1.1 1.3 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase Nucleopor_Nup85 PF07575.13 KKK26833.1 - 2e-19 69.6 0.0 2.5e-12 46.2 0.0 2.3 2 0 0 2 2 2 2 Nup85 Nucleoporin Myc_N PF01056.18 KKK26833.1 - 0.13 12.1 0.9 0.28 11.0 0.9 1.5 1 0 0 1 1 1 0 Myc amino-terminal region Cytomega_UL84 PF06284.11 KKK26833.1 - 0.15 10.5 1.9 0.26 9.7 1.9 1.3 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein BSP_II PF05432.11 KKK26833.1 - 2.5 7.7 10.4 0.13 11.9 4.9 1.6 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) LRR_4 PF12799.7 KKK26834.1 - 7e-12 45.4 2.5 0.45 11.0 0.0 7.2 5 2 3 8 8 8 2 Leucine Rich repeats (2 copies) TPR_2 PF07719.17 KKK26834.1 - 2.6e-07 30.2 4.3 0.053 13.6 0.3 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KKK26834.1 - 4.2e-06 26.3 3.0 0.78 9.7 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat F-box PF00646.33 KKK26834.1 - 8.6e-06 25.5 0.2 2.8e-05 23.8 0.2 1.9 1 0 0 1 1 1 1 F-box domain TPR_16 PF13432.6 KKK26834.1 - 5.9e-05 23.6 1.8 0.008 16.8 0.1 2.6 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 KKK26834.1 - 0.00087 19.8 2.5 0.011 16.2 0.8 2.3 1 1 1 2 2 2 1 Tetratricopeptide repeat BTAD PF03704.17 KKK26834.1 - 0.0011 19.4 1.5 0.011 16.1 1.5 2.1 1 1 0 1 1 1 1 Bacterial transcriptional activator domain LRR_8 PF13855.6 KKK26834.1 - 0.0015 18.2 5.1 11 5.9 0.1 5.7 4 3 1 5 5 5 0 Leucine rich repeat F-box-like PF12937.7 KKK26834.1 - 0.0034 17.2 0.1 0.0067 16.3 0.1 1.5 1 0 0 1 1 1 1 F-box-like TPR_12 PF13424.6 KKK26834.1 - 0.0038 17.5 4.2 0.38 11.1 0.3 3.1 1 1 0 2 2 2 1 Tetratricopeptide repeat PRANC PF09372.10 KKK26834.1 - 0.008 16.5 0.0 0.017 15.5 0.0 1.5 1 0 0 1 1 1 1 PRANC domain NARP1 PF12569.8 KKK26834.1 - 0.0083 15.1 1.6 0.011 14.6 1.6 1.1 1 0 0 1 1 1 1 NMDA receptor-regulated protein 1 DUF1207 PF06727.11 KKK26834.1 - 0.0093 14.9 0.1 0.017 14.1 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1207) LRR_1 PF00560.33 KKK26834.1 - 0.018 15.5 1.8 2.5e+02 2.9 0.0 6.3 8 0 0 8 8 4 0 Leucine Rich Repeat TPR_11 PF13414.6 KKK26834.1 - 0.033 13.9 1.8 0.47 10.2 0.1 2.8 1 1 2 3 3 3 0 TPR repeat TPR_14 PF13428.6 KKK26834.1 - 0.053 14.4 2.5 9.7 7.3 0.2 3.2 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 KKK26834.1 - 0.089 12.7 0.1 7.1 6.7 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF742 PF05331.11 KKK26834.1 - 0.13 12.1 0.0 0.28 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF742) TPR_9 PF13371.6 KKK26834.1 - 0.14 12.3 2.1 16 5.8 0.3 2.8 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 KKK26834.1 - 0.24 11.5 1.3 35 4.7 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat ADIP PF11559.8 KKK26835.1 - 9.6e-46 155.6 7.6 9.6e-46 155.6 7.6 2.9 3 0 0 3 3 3 1 Afadin- and alpha -actinin-Binding Golgin_A5 PF09787.9 KKK26835.1 - 0.0029 17.1 9.2 0.0029 17.1 9.2 2.3 3 1 1 4 4 4 1 Golgin subfamily A member 5 APG6_N PF17675.1 KKK26835.1 - 0.0058 17.2 5.0 0.0058 17.2 5.0 4.0 3 2 0 3 3 2 1 Apg6 coiled-coil region DUF641 PF04859.12 KKK26835.1 - 0.077 13.3 12.2 0.38 11.1 2.5 3.6 2 1 1 3 3 3 0 Plant protein of unknown function (DUF641) FlaC_arch PF05377.11 KKK26835.1 - 0.083 13.3 4.5 0.34 11.3 0.5 3.2 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) RepA_C PF04796.12 KKK26835.1 - 0.092 12.8 0.5 0.57 10.2 0.3 2.2 2 0 0 2 2 2 0 Plasmid encoded RepA protein KASH_CCD PF14662.6 KKK26835.1 - 0.096 12.5 14.8 0.033 14.0 9.5 2.4 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH DUF724 PF05266.14 KKK26835.1 - 0.33 10.8 11.8 0.029 14.2 5.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF724) DUF2304 PF10066.9 KKK26835.1 - 0.37 11.0 0.8 0.64 10.3 0.8 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2304) AKNA PF12443.8 KKK26835.1 - 0.42 11.3 11.1 0.15 12.7 3.4 3.9 3 2 1 4 4 4 0 AT-hook-containing transcription factor TMPIT PF07851.13 KKK26835.1 - 2.1 7.5 4.6 4.2 6.5 4.6 1.5 1 0 0 1 1 1 0 TMPIT-like protein V_ATPase_I PF01496.19 KKK26835.1 - 2.3 6.0 4.9 5.9 4.7 4.9 1.6 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF1664 PF07889.12 KKK26835.1 - 5.1 7.1 6.0 13 5.8 4.2 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Spc7 PF08317.11 KKK26835.1 - 6.3 5.6 17.0 0.077 11.9 7.6 2.4 3 0 0 3 3 3 0 Spc7 kinetochore protein DUF3886 PF13025.6 KKK26835.1 - 7.6 6.8 13.0 0.55 10.5 4.4 3.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3886) VPS38 PF17649.1 KKK26835.1 - 7.7 5.3 7.5 6 5.6 3.3 2.0 1 1 1 2 2 2 0 Vacuolar protein sorting 38 DUF3090 PF11290.8 KKK26835.1 - 8.4 6.2 8.1 1.4 8.7 0.5 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3090) DUF948 PF06103.11 KKK26835.1 - 9 6.6 10.0 2.9 8.2 0.7 3.7 2 2 1 4 4 4 0 Bacterial protein of unknown function (DUF948) V-ATPase_G PF03179.15 KKK26836.1 - 3.5e-33 114.3 16.7 4.2e-33 114.0 16.7 1.1 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit ATP-synt_B PF00430.18 KKK26836.1 - 0.01 15.9 21.0 0.015 15.4 11.4 2.1 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) S_layer_C PF05124.12 KKK26836.1 - 0.017 15.1 3.5 0.019 15.0 3.5 1.1 1 0 0 1 1 1 0 S-layer like family, C-terminal region AAA_15 PF13175.6 KKK26836.1 - 0.028 14.2 7.6 0.029 14.1 7.6 1.0 1 0 0 1 1 1 0 AAA ATPase domain ECM11 PF15463.6 KKK26836.1 - 0.097 13.3 10.3 0.23 12.0 10.3 1.5 1 1 0 1 1 1 0 Extracellular mutant protein 11 DUF5401 PF17380.2 KKK26836.1 - 0.2 9.7 11.9 0.22 9.6 11.9 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5401) DUF2203 PF09969.9 KKK26836.1 - 0.2 12.4 5.4 0.24 12.1 5.4 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) V-ATPase_G_2 PF16999.5 KKK26836.1 - 0.25 11.8 16.5 0.43 11.0 16.5 1.4 1 1 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit DUF3552 PF12072.8 KKK26836.1 - 0.57 9.6 20.5 0.04 13.3 12.4 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) Endonuc_Holl PF10107.9 KKK26836.1 - 0.72 9.7 10.0 1.3 8.8 10.0 1.5 1 1 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase ATP11 PF06644.11 KKK26836.1 - 4.4 7.0 11.7 5 6.8 11.7 1.0 1 0 0 1 1 1 0 ATP11 protein DUF883 PF05957.13 KKK26836.1 - 4.6 7.9 9.4 22 5.7 9.4 2.1 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) PET117 PF15786.5 KKK26837.1 - 6.3e-23 80.8 1.7 7.3e-23 80.6 1.7 1.0 1 0 0 1 1 1 1 PET assembly of cytochrome c oxidase, mitochondrial EMC3_TMCO1 PF01956.16 KKK26837.1 - 0.03 14.0 0.3 0.034 13.9 0.3 1.1 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like DUF5639 PF18690.1 KKK26837.1 - 0.042 14.0 0.3 0.069 13.3 0.3 1.4 1 1 0 1 1 1 0 Family of unknown function (DUF5639) DUF3824 PF12868.7 KKK26837.1 - 0.058 14.1 0.1 0.07 13.8 0.1 1.1 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) IDO PF01231.18 KKK26838.1 - 2.7e-32 112.1 0.0 3.7e-32 111.7 0.0 1.2 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase DnaJ PF00226.31 KKK26839.1 - 2.6e-09 37.1 0.0 5.9e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain INO80_Ies4 PF08193.11 KKK26840.1 - 8.4e-70 235.5 25.6 2.6e-67 227.3 25.6 2.0 1 1 0 1 1 1 1 INO80 complex subunit Ies4 Pol_alpha_B_N PF08418.10 KKK26840.1 - 9.4 6.1 9.3 2.1 8.3 5.2 1.8 2 0 0 2 2 2 0 DNA polymerase alpha subunit B N-terminal DUF3439 PF11921.8 KKK26841.1 - 1.3 9.0 5.0 2.3 8.2 5.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) 4HBT PF03061.22 KKK26842.1 - 1.9e-13 50.6 0.0 3.4e-13 49.7 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily Glyco_hydro_92 PF07971.12 KKK26843.1 - 9.5e-148 492.9 0.0 1.1e-147 492.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 KKK26843.1 - 1.6e-59 201.7 0.5 2.3e-59 201.2 0.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain Gln-synt_N PF03951.19 KKK26843.1 - 0.086 12.6 0.1 0.2 11.4 0.1 1.5 1 0 0 1 1 1 0 Glutamine synthetase, beta-Grasp domain DUF3431 PF11913.8 KKK26844.1 - 9.3e-92 306.7 0.0 1.2e-91 306.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) RNase_P_p30 PF01876.16 KKK26845.1 - 6.3e-64 215.4 0.0 8.2e-64 215.0 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit p30 tRNA-synt_1 PF00133.22 KKK26847.1 - 8e-224 744.3 0.0 9.7e-223 740.8 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KKK26847.1 - 1.1e-32 113.1 0.9 1.1e-32 113.1 0.9 2.0 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 KKK26847.1 - 1.7e-12 46.8 0.2 1.1e-05 24.4 0.0 4.6 5 1 0 5 5 5 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 KKK26847.1 - 7.2e-08 32.2 0.0 0.00011 21.8 0.0 2.6 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 KKK26847.1 - 0.025 13.9 0.0 0.2 11.0 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain Tox-SHH PF15652.6 KKK26847.1 - 0.12 13.3 1.7 0.54 11.2 0.7 2.6 2 0 0 2 2 2 0 HNH/Endo VII superfamily toxin with a SHH signature PepSY PF03413.19 KKK26847.1 - 3.2 8.4 7.8 2.2 8.9 0.0 3.4 3 0 0 3 3 3 0 Peptidase propeptide and YPEB domain Pkinase PF00069.25 KKK26848.1 - 2.2e-67 227.2 0.0 2.6e-67 227.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK26848.1 - 2.4e-19 69.6 0.0 3.4e-19 69.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KKK26848.1 - 4.2e-08 33.4 0.3 8.1e-05 22.7 0.1 2.6 2 1 1 3 3 3 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KKK26848.1 - 0.003 16.4 0.0 0.0052 15.6 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KKK26848.1 - 0.01 15.2 0.0 0.018 14.4 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.14 KKK26848.1 - 0.015 14.7 0.0 0.022 14.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 KKK26848.1 - 0.047 13.3 0.1 0.047 13.3 0.1 2.0 3 0 0 3 3 3 0 Choline/ethanolamine kinase MFS_1 PF07690.16 KKK26849.1 - 4.9e-20 71.7 27.8 2.6e-10 39.8 1.5 3.1 3 0 0 3 3 3 3 Major Facilitator Superfamily MFS_2 PF13347.6 KKK26849.1 - 1.9e-06 26.7 13.6 4.3e-06 25.6 2.8 2.7 3 0 0 3 3 3 2 MFS/sugar transport protein MFS_1_like PF12832.7 KKK26849.1 - 0.00032 19.7 7.2 0.0085 15.0 0.1 2.9 3 0 0 3 3 3 2 MFS_1 like family zf-rbx1 PF12678.7 KKK26850.1 - 5.4e-09 36.2 5.0 1.8e-08 34.6 5.0 2.0 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 KKK26850.1 - 1e-07 32.2 9.1 5.5e-07 29.8 9.1 2.1 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KKK26850.1 - 9.5e-07 28.6 3.2 1.9e-06 27.6 3.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KKK26850.1 - 3.2e-06 27.1 2.7 6.7e-06 26.0 2.7 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KKK26850.1 - 2.8e-05 23.9 5.6 0.00016 21.5 2.2 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 KKK26850.1 - 4.1e-05 23.1 0.6 9.3e-05 22.0 0.6 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3HC4_2 PF13923.6 KKK26850.1 - 7.5e-05 22.5 3.5 7.5e-05 22.5 3.5 2.0 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KKK26850.1 - 9.5e-05 22.3 3.1 0.00037 20.4 3.4 1.8 1 1 1 2 2 2 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 KKK26850.1 - 0.0093 16.0 4.3 0.046 13.8 4.3 2.0 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 KKK26850.1 - 0.02 14.7 5.4 0.052 13.4 5.4 1.7 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KKK26850.1 - 0.028 14.5 1.1 0.069 13.3 1.1 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING-like PF08746.11 KKK26850.1 - 0.22 11.9 1.9 0.45 10.9 1.9 1.5 1 0 0 1 1 1 0 RING-like domain CopD PF05425.13 KKK26850.1 - 0.61 10.5 6.0 1.4 9.4 6.0 1.7 1 0 0 1 1 1 0 Copper resistance protein D zf-RING_11 PF17123.5 KKK26850.1 - 2.2 8.1 8.1 0.37 10.6 0.2 2.7 3 0 0 3 3 3 0 RING-like zinc finger zf-RING_4 PF14570.6 KKK26850.1 - 3.1 7.7 4.7 1.4 8.7 1.8 1.8 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Ureidogly_lyase PF04115.12 KKK26851.1 - 3.2e-62 209.6 0.1 5.4e-31 107.8 0.0 2.1 2 0 0 2 2 2 2 Ureidoglycolate lyase Myc_N PF01056.18 KKK26851.1 - 0.0028 17.6 0.1 0.0033 17.4 0.1 1.1 1 0 0 1 1 1 1 Myc amino-terminal region RNA_pol_3_Rpc31 PF11705.8 KKK26851.1 - 0.018 15.3 0.4 0.041 14.1 0.4 1.6 1 1 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 MutS_V PF00488.21 KKK26852.1 - 2.2e-72 243.1 0.0 4.9e-72 241.9 0.0 1.6 2 0 0 2 2 2 1 MutS domain V MutS_III PF05192.18 KKK26852.1 - 2.9e-46 158.1 0.9 1.2e-45 156.1 0.9 2.0 1 1 0 1 1 1 1 MutS domain III MutS_I PF01624.20 KKK26852.1 - 5.7e-21 74.9 0.1 1.9e-20 73.2 0.0 2.0 2 0 0 2 2 2 1 MutS domain I AAA_23 PF13476.6 KKK26852.1 - 0.0089 16.6 0.4 0.53 10.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KKK26852.1 - 0.017 15.5 0.4 1.3 9.4 0.2 2.9 2 1 0 2 2 2 0 AAA ATPase domain AAA_27 PF13514.6 KKK26852.1 - 0.022 14.3 0.0 0.069 12.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KKK26852.1 - 0.058 13.2 0.0 0.16 11.7 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Sec63 PF02889.16 KKK26853.1 - 2.8e-163 541.2 0.0 1.6e-91 306.0 0.0 2.2 2 0 0 2 2 2 2 Sec63 Brl domain Peptidase_S9 PF00326.21 KKK26853.1 - 3.1e-49 167.3 0.0 9.5e-49 165.7 0.0 1.8 2 0 0 2 2 2 1 Prolyl oligopeptidase family DEAD PF00270.29 KKK26853.1 - 2.4e-48 164.2 0.1 2.6e-27 95.7 0.0 3.2 3 0 0 3 3 3 2 DEAD/DEAH box helicase Helicase_PWI PF18149.1 KKK26853.1 - 5e-30 103.9 0.1 1.3e-29 102.6 0.1 1.8 1 0 0 1 1 1 1 N-terminal helicase PWI domain ResIII PF04851.15 KKK26853.1 - 3.2e-25 89.1 0.0 2.8e-13 50.2 0.0 2.5 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KKK26853.1 - 4.7e-10 39.8 0.0 3.6e-07 30.5 0.0 3.6 2 1 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 KKK26853.1 - 1.2e-05 25.6 1.9 0.24 11.7 0.2 4.1 3 1 0 3 3 3 2 AAA domain Abhydrolase_1 PF00561.20 KKK26853.1 - 0.0022 17.7 0.1 0.0043 16.7 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold AXE1 PF05448.12 KKK26853.1 - 0.0032 16.2 0.0 0.089 11.5 0.0 2.4 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) AAA_19 PF13245.6 KKK26853.1 - 0.0046 17.3 0.0 3.2 8.1 0.0 2.8 2 0 0 2 2 2 1 AAA domain PhoH PF02562.16 KKK26853.1 - 0.0058 16.1 0.0 0.3 10.5 0.0 2.5 2 0 0 2 2 2 1 PhoH-like protein T2SSE PF00437.20 KKK26853.1 - 0.0065 15.6 0.0 1.3 8.1 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein Phage_TAC_5 PF08890.11 KKK26853.1 - 0.071 13.1 1.4 0.18 11.8 1.4 1.7 1 0 0 1 1 1 0 Phage XkdN-like tail assembly chaperone protein, TAC AAA_7 PF12775.7 KKK26853.1 - 0.17 11.4 0.0 8 5.9 0.0 2.6 2 0 0 2 2 2 0 P-loop containing dynein motor region AMP-binding PF00501.28 KKK26855.1 - 5.8e-38 130.6 0.0 4.6e-37 127.6 0.0 2.1 1 1 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 KKK26855.1 - 2.4e-06 27.4 2.0 6e-06 26.1 2.0 1.8 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus FeoA PF04023.14 KKK26855.1 - 0.088 13.1 0.0 0.23 11.8 0.0 1.6 1 0 0 1 1 1 0 FeoA domain HTH_AsnC-type PF13404.6 KKK26856.1 - 0.044 13.6 0.1 0.091 12.6 0.1 1.5 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain MFS_1 PF07690.16 KKK26857.1 - 2.3e-39 135.3 43.8 2.3e-39 135.3 43.8 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KKK26857.1 - 8.9e-19 67.3 11.2 2.2e-18 66.0 11.2 1.6 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KKK26857.1 - 9.5e-13 47.8 14.0 3.7e-11 42.5 6.7 2.7 2 1 0 2 2 2 2 Sugar (and other) transporter ADH_N PF08240.12 KKK26858.1 - 6.7e-26 90.3 4.5 1e-25 89.7 4.5 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KKK26858.1 - 6.7e-15 55.2 0.0 1.2e-14 54.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KKK26858.1 - 0.0015 18.1 0.2 0.0028 17.2 0.1 1.4 2 0 0 2 2 2 1 Glucose dehydrogenase C-terminus NAD_binding_10 PF13460.6 KKK26858.1 - 0.0021 18.0 0.0 0.0032 17.4 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding 2-Hacid_dh_C PF02826.19 KKK26858.1 - 0.016 14.5 0.0 0.026 13.9 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ELFV_dehydrog PF00208.21 KKK26858.1 - 0.019 14.7 0.1 0.031 14.0 0.1 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ADH_zinc_N_2 PF13602.6 KKK26858.1 - 0.02 16.0 0.0 0.054 14.6 0.0 1.8 1 1 0 1 1 1 0 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KKK26858.1 - 0.1 11.9 0.1 0.25 10.6 0.1 1.5 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Brix PF04427.18 KKK26859.1 - 4.6e-36 124.7 0.0 6.1e-36 124.3 0.0 1.2 1 0 0 1 1 1 1 Brix domain Tim17 PF02466.19 KKK26860.1 - 1.9e-14 53.9 0.4 3.7e-14 53.0 0.4 1.4 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Mrx7 PF10906.8 KKK26861.1 - 2.2e-13 50.3 0.0 2.9e-13 49.8 0.0 1.2 1 0 0 1 1 1 1 MIOREX complex component 7 Y_phosphatase PF00102.27 KKK26862.1 - 3.6e-51 174.0 0.0 1.1e-50 172.4 0.0 1.7 1 1 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 KKK26862.1 - 0.0042 17.2 0.0 0.012 15.7 0.0 1.8 2 0 0 2 2 2 1 Inositol hexakisphosphate DSPc PF00782.20 KKK26862.1 - 0.0087 15.9 0.1 0.027 14.3 0.1 1.8 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 KKK26862.1 - 0.036 14.0 0.0 0.078 12.9 0.0 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family Mid2 PF04478.12 KKK26864.1 - 2.6e-06 27.3 0.8 2.6e-06 27.3 0.8 3.3 1 1 2 3 3 3 1 Mid2 like cell wall stress sensor Presenilin PF01080.17 KKK26864.1 - 0.0023 16.8 3.7 0.003 16.4 3.7 1.3 1 0 0 1 1 1 1 Presenilin PRCC PF10253.9 KKK26864.1 - 0.0034 18.2 10.4 0.0053 17.6 10.4 1.4 1 0 0 1 1 1 1 Mitotic checkpoint regulator, MAD2B-interacting SOG2 PF10428.9 KKK26864.1 - 0.0098 15.1 27.1 0.011 14.9 27.1 1.3 1 0 0 1 1 1 1 RAM signalling pathway protein Macoilin PF09726.9 KKK26864.1 - 0.093 11.3 12.7 0.11 11.1 12.7 1.2 1 0 0 1 1 1 0 Macoilin family Utp14 PF04615.13 KKK26864.1 - 0.23 10.0 7.5 0.25 9.9 7.5 1.1 1 0 0 1 1 1 0 Utp14 protein Plasmodium_Vir PF05795.11 KKK26864.1 - 0.47 9.8 10.6 0.62 9.4 10.6 1.4 1 0 0 1 1 1 0 Plasmodium vivax Vir protein SLC12 PF03522.15 KKK26864.1 - 7.7 5.4 8.8 9.9 5.1 8.8 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Piwi PF02171.17 KKK26865.1 - 6.4e-71 239.1 0.0 9.2e-71 238.5 0.0 1.2 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 KKK26865.1 - 3.4e-18 66.6 0.0 8.1e-18 65.4 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL1 PF08699.10 KKK26865.1 - 9.1e-18 63.7 0.5 3e-17 62.0 0.1 2.1 2 0 0 2 2 2 1 Argonaute linker 1 domain ArgoL2 PF16488.5 KKK26865.1 - 6.4e-13 48.8 0.0 1.7e-12 47.5 0.0 1.8 1 0 0 1 1 1 1 Argonaute linker 2 domain PAZ PF02170.22 KKK26865.1 - 1.6e-12 47.4 0.0 3e-12 46.5 0.0 1.3 1 0 0 1 1 1 1 PAZ domain ArgoMid PF16487.5 KKK26865.1 - 1e-09 38.5 0.0 2.6e-09 37.2 0.0 1.7 1 0 0 1 1 1 1 Mid domain of argonaute Suf PF05843.14 KKK26866.1 - 1.3e-97 327.4 0.2 1.3e-97 327.4 0.2 4.3 4 1 0 4 4 4 2 Suppressor of forked protein (Suf) TPR_14 PF13428.6 KKK26866.1 - 2.1e-05 24.9 0.0 0.013 16.3 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat HAT PF02184.16 KKK26866.1 - 0.0063 16.4 0.1 0.0063 16.4 0.1 2.4 2 0 0 2 2 2 1 HAT (Half-A-TPR) repeat DUF5583 PF17821.1 KKK26866.1 - 0.043 13.8 0.4 0.043 13.8 0.4 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5583) Bromodomain PF00439.25 KKK26867.1 - 1.1e-17 63.9 0.2 1.1e-17 63.9 0.2 2.4 3 0 0 3 3 3 1 Bromodomain Bromo_TP PF07524.13 KKK26867.1 - 5.4e-09 35.9 0.0 2.4e-08 33.9 0.0 2.1 2 0 0 2 2 2 1 Bromodomain associated PBP1_TM PF14812.6 KKK26867.1 - 0.0094 16.3 5.7 0.0094 16.3 5.7 2.5 2 0 0 2 2 2 1 Transmembrane domain of transglycosylase PBP1 at N-terminal HisKA_3 PF07730.13 KKK26867.1 - 0.018 15.5 0.8 0.24 11.9 0.0 3.0 2 0 0 2 2 2 0 Histidine kinase Talin_middle PF09141.10 KKK26867.1 - 0.046 13.7 0.5 0.34 10.9 0.3 2.4 2 0 0 2 2 2 0 Talin, middle domain CENP-B_dimeris PF09026.10 KKK26867.1 - 0.54 10.7 7.1 2.5 8.6 7.1 2.1 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF4407 PF14362.6 KKK26867.1 - 5.9 6.2 8.2 11 5.3 8.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) bZIP_1 PF00170.21 KKK26868.1 - 1.8e-05 24.7 8.1 1.8e-05 24.7 8.1 1.7 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 KKK26868.1 - 0.00071 19.6 8.8 0.0018 18.3 8.8 1.7 1 0 0 1 1 1 1 Basic region leucine zipper Pex19 PF04614.12 KKK26869.1 - 4.8e-74 249.2 8.9 5.4e-74 249.0 8.9 1.0 1 0 0 1 1 1 1 Pex19 protein family T2SSF PF00482.23 KKK26869.1 - 0.17 11.8 1.7 4.3 7.3 0.1 3.1 3 1 0 3 3 3 0 Type II secretion system (T2SS), protein F GET2 PF08690.10 KKK26869.1 - 0.55 9.8 11.9 0.073 12.7 4.5 2.3 1 1 1 2 2 2 0 GET complex subunit GET2 DNA_pol_phi PF04931.13 KKK26869.1 - 0.58 8.2 3.7 0.73 7.9 3.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi VanZ PF04892.12 KKK26870.1 - 4.5e-07 30.6 0.7 9.2e-07 29.6 0.7 1.5 1 1 0 1 1 1 1 VanZ like family Virul_fac_BrkB PF03631.15 KKK26870.1 - 0.11 12.1 0.3 0.15 11.7 0.3 1.2 1 0 0 1 1 1 0 Virulence factor BrkB Stm1_N PF09598.10 KKK26871.1 - 1.8e-16 60.7 4.2 1.8e-16 60.7 4.2 4.6 3 1 0 3 3 3 1 Stm1 APH PF01636.23 KKK26872.1 - 0.00076 19.5 0.1 0.0011 18.9 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family PS-DH PF14765.6 KKK26873.1 - 1.2e-51 175.8 0.8 2e-51 175.0 0.8 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.10 KKK26873.1 - 2.9e-51 173.9 0.5 2e-50 171.2 0.1 2.4 2 0 0 2 2 2 1 KR domain adh_short PF00106.25 KKK26873.1 - 3.6e-12 46.2 0.2 2.3e-11 43.5 0.0 2.3 3 0 0 3 3 3 1 short chain dehydrogenase PP-binding PF00550.25 KKK26873.1 - 1.7e-05 25.1 0.1 4.3e-05 23.8 0.1 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site ASF1_hist_chap PF04729.13 KKK26874.1 - 1.2e-73 246.1 0.0 1.7e-73 245.6 0.0 1.2 1 0 0 1 1 1 1 ASF1 like histone chaperone Nop14 PF04147.12 KKK26874.1 - 0.0017 16.7 15.1 0.0022 16.3 15.1 1.0 1 0 0 1 1 1 1 Nop14-like family BUD22 PF09073.10 KKK26874.1 - 1 8.6 9.9 1.2 8.3 9.9 1.1 1 0 0 1 1 1 0 BUD22 GCP5-Mod21 PF14609.6 KKK26874.1 - 1.8 6.8 6.2 2.3 6.4 6.2 1.1 1 0 0 1 1 1 0 gamma-Tubulin ring complex non-core subunit mod21 Lgl_C PF08596.10 KKK26875.1 - 6.6e-136 453.1 0.0 1.5e-135 452.0 0.0 1.6 2 0 0 2 2 2 1 Lethal giant larvae(Lgl) like, C-terminal ANAPC4_WD40 PF12894.7 KKK26875.1 - 9.8e-07 29.0 0.0 9.5 6.6 0.0 6.0 5 2 1 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KKK26875.1 - 9.5e-06 26.3 4.6 0.23 12.4 0.1 5.7 6 0 0 6 6 6 2 WD domain, G-beta repeat adh_short PF00106.25 KKK26876.1 - 2.9e-42 144.4 0.1 3.9e-42 143.9 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KKK26876.1 - 4e-27 95.3 0.5 7.4e-27 94.4 0.5 1.4 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KKK26876.1 - 2e-06 27.8 0.2 3.2e-06 27.2 0.2 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 KKK26876.1 - 0.00057 19.3 0.0 0.00072 19.0 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 KKK26876.1 - 0.008 15.7 0.4 0.014 14.8 0.4 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KKK26876.1 - 0.035 13.2 0.1 0.059 12.5 0.1 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain MFS_1 PF07690.16 KKK26877.1 - 1.8e-41 142.2 58.8 4.7e-40 137.6 57.8 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily Trp_oprn_chp PF09534.10 KKK26877.1 - 1.7 8.4 8.0 0.41 10.4 0.3 2.5 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) FMN_red PF03358.15 KKK26878.1 - 9.8e-30 103.3 0.0 1.3e-29 103.0 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 KKK26878.1 - 2.8e-07 30.4 0.0 4e-07 30.0 0.0 1.3 1 1 0 1 1 1 1 Flavodoxin-like fold Fungal_trans PF04082.18 KKK26879.1 - 3.4e-09 36.1 0.0 6.1e-09 35.3 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain K_trans PF02705.16 KKK26880.1 - 1.8e-179 597.7 18.7 2.1e-179 597.5 18.7 1.0 1 0 0 1 1 1 1 K+ potassium transporter DUF4064 PF13273.6 KKK26880.1 - 0.24 11.7 14.4 0.019 15.2 5.9 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF4064) PaaX PF07848.12 KKK26881.1 - 0.088 13.0 0.1 1.8 8.9 0.0 2.2 1 1 1 2 2 2 0 PaaX-like protein GntR PF00392.21 KKK26881.1 - 0.097 12.3 0.3 0.61 9.8 0.0 2.0 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family TauD PF02668.16 KKK26882.1 - 5.6e-28 98.5 0.1 8.9e-28 97.8 0.1 1.3 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family LssY_C PF14067.6 KKK26882.1 - 0.15 11.6 0.0 0.95 9.0 0.0 2.1 2 0 0 2 2 2 0 LssY C-terminus DUF3439 PF11921.8 KKK26882.1 - 4.4 7.3 8.7 7.2 6.6 8.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) zf-C2H2_jaz PF12171.8 KKK26883.1 - 0.00076 19.7 3.1 0.0012 19.1 3.1 1.3 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 KKK26883.1 - 0.0016 18.8 1.8 0.003 17.9 1.8 1.5 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-met PF12874.7 KKK26883.1 - 0.004 17.5 0.7 0.0067 16.8 0.7 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-LYAR PF08790.11 KKK26883.1 - 0.032 14.1 0.3 0.064 13.2 0.3 1.5 1 0 0 1 1 1 0 LYAR-type C2HC zinc finger zf-C2H2_2 PF12756.7 KKK26883.1 - 0.045 14.1 0.4 0.07 13.5 0.4 1.2 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 KKK26883.1 - 0.073 14.0 0.8 0.16 12.9 0.8 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger Herpes_capsid PF06112.11 KKK26883.1 - 8.6 6.4 9.9 19 5.3 9.9 1.6 1 1 0 1 1 1 0 Gammaherpesvirus capsid protein DUF1691 PF07950.11 KKK26884.1 - 2.5e-39 134.3 7.2 2.3e-32 111.9 5.5 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1691) Sdh_cyt PF01127.22 KKK26884.1 - 0.0028 17.7 3.1 0.25 11.4 0.9 2.5 2 0 0 2 2 2 2 Succinate dehydrogenase/Fumarate reductase transmembrane subunit MOSP_N PF02707.16 KKK26884.1 - 0.14 11.9 1.1 0.28 10.9 1.1 1.5 1 1 0 1 1 1 0 Major Outer Sheath Protein N-terminal region Amidase PF01425.21 KKK26885.1 - 4.5e-116 388.5 0.1 5.4e-116 388.2 0.1 1.0 1 0 0 1 1 1 1 Amidase ADH_zinc_N PF00107.26 KKK26886.1 - 8.8e-15 54.8 0.0 1.6e-14 54.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KKK26886.1 - 0.054 13.4 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain DUF4265 PF14085.6 KKK26886.1 - 0.073 13.0 0.0 4.9 7.2 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4265) Metallophos PF00149.28 KKK26887.1 - 3.5e-11 44.0 3.7 6.1e-11 43.2 3.7 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase 5_nucleotid_C PF02872.18 KKK26887.1 - 0.02 15.1 0.0 0.038 14.2 0.0 1.5 1 0 0 1 1 1 0 5'-nucleotidase, C-terminal domain Transket_pyr PF02779.24 KKK26888.1 - 1.7e-45 154.9 0.0 2.4e-45 154.4 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KKK26888.1 - 3e-35 120.8 0.0 1.3e-34 118.8 0.0 2.0 2 0 0 2 2 2 1 Transketolase, C-terminal domain DUF4157 PF13699.6 KKK26889.1 - 0.022 15.0 3.4 0.04 14.1 1.9 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4157) Snf7 PF03357.21 KKK26889.1 - 0.03 13.9 7.6 0.038 13.6 7.6 1.1 1 0 0 1 1 1 0 Snf7 ThiS PF02597.20 KKK26889.1 - 0.14 12.9 1.1 0.26 12.0 0.2 1.9 2 0 0 2 2 2 0 ThiS family DUF1045 PF06299.12 KKK26889.1 - 2 8.4 7.4 16 5.4 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1045) bZIP_2 PF07716.15 KKK26890.1 - 2e-11 43.8 16.6 2e-11 43.8 16.6 2.5 1 1 1 2 2 2 2 Basic region leucine zipper bZIP_1 PF00170.21 KKK26890.1 - 2.1e-06 27.7 18.6 4.2e-06 26.8 18.6 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 KKK26890.1 - 0.00047 20.6 14.9 0.00099 19.6 14.9 1.5 1 0 0 1 1 1 1 bZIP Maf transcription factor APG6_N PF17675.1 KKK26890.1 - 0.038 14.5 13.8 0.078 13.5 13.8 1.5 1 0 0 1 1 1 0 Apg6 coiled-coil region Spc24 PF08286.11 KKK26890.1 - 0.052 13.8 0.6 0.11 12.7 0.6 1.5 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 Bystin PF05291.11 KKK26891.1 - 2.3e-131 437.4 0.0 3e-131 437.0 0.0 1.1 1 0 0 1 1 1 1 Bystin SPRY PF00622.28 KKK26892.1 - 0.041 14.0 0.0 6.9 6.8 0.0 2.6 2 0 0 2 2 2 0 SPRY domain MFS_1 PF07690.16 KKK26893.1 - 1.8e-32 112.7 28.3 1.8e-32 112.7 28.3 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Ceramidase PF05875.12 KKK26893.1 - 6.3 6.1 10.2 1.1 8.6 3.4 2.5 2 1 1 3 3 3 0 Ceramidase HAD PF12710.7 KKK26894.1 - 1.2e-23 84.5 0.0 1.6e-23 84.1 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 KKK26894.1 - 6.8e-06 25.7 0.0 0.047 13.1 0.0 2.1 2 0 0 2 2 2 2 Putative Phosphatase Hydrolase PF00702.26 KKK26894.1 - 0.044 14.1 0.4 0.19 12.0 0.1 2.3 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase UMPH-1 PF05822.12 KKK26894.1 - 0.18 11.3 0.0 0.67 9.4 0.0 1.9 2 0 0 2 2 2 0 Pyrimidine 5'-nucleotidase (UMPH-1) MFS_1 PF07690.16 KKK26895.1 - 5.3e-25 88.1 26.4 4e-13 49.0 12.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KKK26895.1 - 0.00013 21.0 8.6 0.0027 16.7 0.4 2.1 1 1 0 2 2 2 2 MFS_1 like family Sugar_tr PF00083.24 KKK26895.1 - 0.011 14.6 13.4 0.087 11.7 13.4 2.0 1 1 0 1 1 1 0 Sugar (and other) transporter AA_permease_2 PF13520.6 KKK26897.1 - 8.1e-69 232.5 40.0 1.1e-68 232.0 40.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KKK26897.1 - 4.2e-23 81.7 33.5 5.7e-23 81.3 33.5 1.1 1 0 0 1 1 1 1 Amino acid permease p450 PF00067.22 KKK26898.1 - 1.8e-66 224.8 0.0 2.4e-66 224.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Sigma70_ECF PF07638.11 KKK26899.1 - 0.031 14.2 3.3 0.067 13.1 3.3 1.5 1 0 0 1 1 1 0 ECF sigma factor D-ser_dehydrat PF14031.6 KKK26900.1 - 6.8e-21 74.7 0.0 1.8e-20 73.4 0.0 1.8 1 0 0 1 1 1 1 Putative serine dehydratase domain Ala_racemase_N PF01168.20 KKK26900.1 - 6.1e-12 45.6 0.1 1.1e-11 44.8 0.1 1.4 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Fungal_trans PF04082.18 KKK26901.1 - 0.047 12.7 2.8 0.38 9.7 2.8 2.4 1 1 0 1 1 1 0 Fungal specific transcription factor domain CoA_trans PF01144.23 KKK26902.1 - 1.3e-93 312.3 2.9 1.2e-59 201.3 0.2 2.1 2 0 0 2 2 2 2 Coenzyme A transferase Mal_decarbox_Al PF16957.5 KKK26902.1 - 0.0055 15.1 0.2 0.01 14.2 0.2 1.4 1 0 0 1 1 1 1 Malonate decarboxylase, alpha subunit, transporter AcetylCoA_hyd_C PF13336.6 KKK26902.1 - 0.013 15.4 0.8 0.025 14.5 0.0 1.8 2 0 0 2 2 2 0 Acetyl-CoA hydrolase/transferase C-terminal domain FAS_I_H PF18314.1 KKK26903.1 - 5.6e-78 261.2 0.0 5.6e-78 261.2 0.0 2.0 2 0 0 2 2 2 1 Fatty acid synthase type I helical domain Fas_alpha_ACP PF18325.1 KKK26903.1 - 6.5e-76 254.2 0.0 1.2e-75 253.3 0.0 1.5 1 0 0 1 1 1 1 Fatty acid synthase subunit alpha Acyl carrier domain ketoacyl-synt PF00109.26 KKK26903.1 - 8.3e-22 78.0 0.5 1.8e-21 76.9 0.0 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACPS PF01648.20 KKK26903.1 - 3e-18 66.0 0.0 6.4e-18 64.9 0.0 1.6 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Ketoacyl-synt_C PF02801.22 KKK26903.1 - 2.4e-12 46.9 0.0 6.3e-12 45.6 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.25 KKK26903.1 - 5.3e-06 26.0 0.0 4.5e-05 23.0 0.0 2.3 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 KKK26903.1 - 0.00051 20.0 0.0 0.002 18.1 0.0 2.0 1 0 0 1 1 1 1 KR domain RbsD_FucU PF05025.13 KKK26903.1 - 0.053 13.9 0.0 0.23 11.9 0.0 2.1 2 0 0 2 2 2 0 RbsD / FucU transport protein family DUF5102 PF17104.5 KKK26903.1 - 0.059 13.4 0.8 0.34 10.9 0.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5102) DUF1031 PF06275.11 KKK26903.1 - 0.18 12.1 0.1 13 6.1 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1031) 4PPT_N PF17837.1 KKK26903.1 - 0.26 11.4 2.7 2.4 8.3 2.7 2.4 1 1 0 1 1 1 0 4'-phosphopantetheinyl transferase N-terminal domain TRM PF02005.16 KKK26904.1 - 7.6e-113 377.5 0.0 1.9e-98 330.1 0.0 2.1 2 0 0 2 2 2 2 N2,N2-dimethylguanosine tRNA methyltransferase Met_10 PF02475.16 KKK26904.1 - 0.00044 20.1 0.0 0.00079 19.2 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein zf-CCHC_3 PF13917.6 KKK26904.1 - 3.2 7.8 4.8 8.7 6.4 0.3 2.4 2 0 0 2 2 2 0 Zinc knuckle Trypan_PARP PF05887.11 KKK26904.1 - 8.6 6.3 9.6 3.6 7.6 3.4 2.5 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) HMGL-like PF00682.19 KKK26906.1 - 3.9e-79 265.9 0.0 5.7e-79 265.4 0.0 1.2 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.10 KKK26906.1 - 1.8e-21 76.4 0.0 3.8e-21 75.4 0.0 1.6 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain DEAD PF00270.29 KKK26907.1 - 1.5e-46 158.4 0.8 2.2e-46 157.8 0.1 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KKK26907.1 - 4.1e-31 107.6 0.2 3.9e-29 101.2 0.1 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain UTP25 PF06862.12 KKK26907.1 - 0.00082 18.3 1.4 0.0073 15.1 0.1 3.0 2 1 1 3 3 3 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Ribosomal_S7 PF00177.21 KKK26908.1 - 2.3e-35 121.5 1.8 3.2e-35 120.9 1.8 1.2 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e AMP-binding PF00501.28 KKK26909.1 - 3e-67 227.1 0.0 1.2e-37 129.5 0.0 3.9 2 2 0 2 2 2 2 AMP-binding enzyme DUF4032 PF13224.6 KKK26909.1 - 0.055 13.3 0.2 7.9 6.3 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4032) RNR_inhib PF08591.10 KKK26910.1 - 9.8e-24 84.7 0.3 2.4e-23 83.5 0.0 1.8 2 0 0 2 2 2 1 Ribonucleotide reductase inhibitor SDA1 PF05285.12 KKK26911.1 - 4.5e-96 322.3 40.6 4.5e-96 322.3 40.6 2.9 2 1 0 2 2 2 1 SDA1 NUC130_3NT PF08158.12 KKK26911.1 - 3.7e-22 78.4 0.1 9.1e-22 77.1 0.1 1.7 1 0 0 1 1 1 1 NUC130/3NT domain Tho2 PF11262.8 KKK26911.1 - 2.2 7.4 0.0 2.2 7.4 0.0 2.8 3 0 0 3 3 3 0 Transcription factor/nuclear export subunit protein 2 DUF4072 PF13284.6 KKK26911.1 - 7.1 7.2 6.9 8.5 6.9 0.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4072) Amidase PF01425.21 KKK26912.1 - 2e-77 261.1 0.0 2.8e-68 230.9 0.4 2.1 1 1 1 2 2 2 2 Amidase T3SS_LEE_assoc PF13327.6 KKK26912.1 - 0.018 15.1 0.1 0.039 14.0 0.1 1.5 1 0 0 1 1 1 0 Type III secretion system subunit PDEase_II PF02112.15 KKK26913.1 - 2.3e-53 181.5 0.0 9.4e-45 153.2 0.0 2.8 2 1 0 2 2 2 2 cAMP phosphodiesterases class-II Lactamase_B PF00753.27 KKK26913.1 - 0.0069 16.4 0.3 0.014 15.4 0.3 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KKK26913.1 - 0.08 12.5 0.1 0.15 11.5 0.1 1.4 1 0 0 1 1 1 0 Beta-lactamase superfamily domain ALO PF04030.14 KKK26914.1 - 6.8e-91 304.7 0.3 8.9e-91 304.3 0.3 1.1 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.23 KKK26914.1 - 4.8e-34 117.1 0.5 7e-34 116.5 0.5 1.3 1 0 0 1 1 1 1 FAD binding domain DUF4045 PF13254.6 KKK26915.1 - 6.5e-135 451.0 34.3 6.5e-135 451.0 34.3 5.1 3 2 0 4 4 4 1 Domain of unknown function (DUF4045) Gelsolin PF00626.22 KKK26915.1 - 6.8e-11 41.9 0.0 2.9e-05 23.9 0.0 3.7 3 0 0 3 3 3 3 Gelsolin repeat Arf PF00025.21 KKK26916.1 - 1.1e-57 194.3 2.4 2.8e-56 189.7 0.2 2.0 2 0 0 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 KKK26916.1 - 2.9e-09 37.2 0.0 4.4e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KKK26916.1 - 3.8e-09 36.3 0.0 4.7e-09 36.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 KKK26916.1 - 1.3e-07 31.2 0.0 1.7e-07 30.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 KKK26916.1 - 3.4e-07 29.8 2.4 4.9e-06 26.0 0.8 2.6 1 1 1 2 2 2 1 G-protein alpha subunit MMR_HSR1 PF01926.23 KKK26916.1 - 7.1e-06 26.1 0.0 1.1e-05 25.5 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 KKK26916.1 - 4.4e-05 23.0 0.0 6e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 KKK26916.1 - 5.2e-05 22.9 0.0 0.00044 19.8 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain HCV_NS1 PF01560.17 KKK26916.1 - 0.042 12.5 0.0 0.048 12.3 0.0 1.1 1 0 0 1 1 1 0 Hepatitis C virus non-structural protein E2/NS1 cobW PF02492.19 KKK26916.1 - 0.06 12.9 0.0 1.3 8.6 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Acetyltransf_1 PF00583.25 KKK26917.1 - 5.4e-05 23.4 0.0 0.00012 22.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KKK26917.1 - 0.0013 19.1 0.0 0.0029 18.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KKK26917.1 - 0.06 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain SPRY PF00622.28 KKK26918.1 - 3.7e-19 69.0 0.1 1.3e-18 67.3 0.0 1.9 2 0 0 2 2 2 1 SPRY domain Peptidase_M24 PF00557.24 KKK26919.1 - 1.5e-61 207.7 0.1 2e-61 207.4 0.1 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 KKK26919.1 - 5.4e-24 84.3 0.0 1.1e-23 83.3 0.0 1.5 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain DnaJ PF00226.31 KKK26920.1 - 6e-17 61.5 0.7 1.6e-16 60.1 0.7 1.8 1 0 0 1 1 1 1 DnaJ domain Sec63 PF02889.16 KKK26920.1 - 7.6e-13 48.2 0.0 4e-08 32.7 0.0 2.2 2 0 0 2 2 2 2 Sec63 Brl domain Zn_clus PF00172.18 KKK26921.1 - 2.3e-08 34.0 14.3 4.8e-08 33.0 14.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3402 PF11882.8 KKK26922.1 - 2.1e-195 650.2 0.0 2.9e-195 649.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3402) N1221 PF07923.13 KKK26922.1 - 2.9e-90 302.4 0.0 4.6e-90 301.7 0.0 1.3 1 0 0 1 1 1 1 N1221-like protein PAP2 PF01569.21 KKK26923.1 - 1.2e-13 50.9 4.2 1.2e-13 50.9 4.2 2.3 1 1 1 2 2 2 1 PAP2 superfamily DUF212 PF02681.14 KKK26923.1 - 0.00024 21.2 0.1 0.06 13.5 0.0 2.4 2 1 0 2 2 2 2 Divergent PAP2 family Dpy-30 PF05186.13 KKK26923.1 - 0.72 9.6 2.9 2.3 8.0 0.4 2.4 2 0 0 2 2 2 0 Dpy-30 motif Elong_Iki1 PF10483.9 KKK26924.1 - 6.4e-101 337.8 0.0 7.4e-101 337.6 0.0 1.0 1 0 0 1 1 1 1 Elongator subunit Iki1 PhoLip_ATPase_C PF16212.5 KKK26925.1 - 3.3e-47 161.3 11.2 3.3e-47 161.3 11.2 2.4 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KKK26925.1 - 2.3e-16 59.2 0.8 5.1e-16 58.1 0.8 1.5 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 KKK26925.1 - 5.5e-14 53.0 2.4 3e-11 44.0 1.1 2.9 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KKK26925.1 - 2e-07 31.0 0.0 5.8e-06 26.3 0.0 2.8 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 KKK26925.1 - 3e-07 30.1 0.3 0.002 17.7 0.0 2.7 2 0 0 2 2 2 2 E1-E2 ATPase Hydrolase_3 PF08282.12 KKK26925.1 - 0.0059 16.4 0.0 0.013 15.2 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Mso1_Sec1_bdg PF14475.6 KKK26926.1 - 9.9e-14 50.7 0.1 1.7e-13 49.9 0.1 1.4 1 0 0 1 1 1 1 Sec1-binding region of Mso1 Ribosomal_L28e PF01778.17 KKK26927.1 - 5.8e-38 130.2 0.2 9.8e-38 129.4 0.2 1.4 1 0 0 1 1 1 1 Ribosomal L28e protein family Mak16 PF04874.14 KKK26927.1 - 2.2e-30 105.2 11.5 2.2e-30 105.2 11.5 2.4 2 0 0 2 2 2 1 Mak16 protein C-terminal region BUD22 PF09073.10 KKK26927.1 - 1.1e-06 28.3 13.6 1.4e-06 27.9 13.6 1.1 1 0 0 1 1 1 1 BUD22 TFIIF_alpha PF05793.12 KKK26927.1 - 0.00075 18.2 22.7 0.00091 17.9 22.7 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Ribosomal_L24e PF01246.20 KKK26927.1 - 0.064 13.5 0.1 0.18 12.1 0.1 1.7 1 0 0 1 1 1 0 Ribosomal protein L24e CxC6 PF18721.1 KKK26927.1 - 0.11 12.8 0.2 0.4 11.0 0.1 1.8 2 0 0 2 2 2 0 CxC6 like cysteine cluster associated with KDZ transposases Nop14 PF04147.12 KKK26927.1 - 0.69 8.1 24.6 0.85 7.7 24.6 1.2 1 0 0 1 1 1 0 Nop14-like family SURF2 PF05477.11 KKK26927.1 - 9.9 5.8 10.1 17 5.0 10.1 1.4 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) ASXH PF13919.6 KKK26928.1 - 1.2e-17 64.3 6.8 1.3e-11 44.7 0.2 2.3 1 1 1 2 2 2 2 Asx homology domain AT_hook PF02178.19 KKK26928.1 - 10 6.4 13.2 1.1 9.4 6.5 2.7 2 0 0 2 2 2 0 AT hook motif Longin PF13774.6 KKK26929.1 - 1.1e-26 92.6 0.5 1.7e-26 92.1 0.5 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.21 KKK26929.1 - 1.5e-13 50.3 0.0 3.1e-13 49.3 0.0 1.6 1 0 0 1 1 1 1 Synaptobrevin SLM4 PF16818.5 KKK26929.1 - 0.019 14.9 0.6 0.51 10.3 0.1 2.2 1 1 1 2 2 2 0 Protein SLM4 RWD PF05773.22 KKK26930.1 - 5.5e-20 71.8 0.0 9.2e-20 71.1 0.0 1.4 1 0 0 1 1 1 1 RWD domain IBR PF01485.21 KKK26930.1 - 1.1e-19 70.3 38.1 1.8e-15 56.9 3.9 4.0 3 1 1 4 4 4 3 IBR domain, a half RING-finger domain zf-RING_2 PF13639.6 KKK26930.1 - 0.0049 17.2 9.6 0.0049 17.2 9.6 4.0 3 1 1 4 4 4 2 Ring finger domain PAC4 PF16093.5 KKK26931.1 - 4e-26 91.0 0.6 5.7e-26 90.5 0.6 1.2 1 0 0 1 1 1 1 Proteasome assembly chaperone 4 Fungal_trans PF04082.18 KKK26932.1 - 1.7e-21 76.5 0.1 3.3e-21 75.5 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK26932.1 - 1.2e-05 25.3 14.2 3.2e-05 24.0 14.2 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain N2227 PF07942.12 KKK26933.1 - 1e-90 303.6 0.0 1.3e-90 303.3 0.0 1.1 1 0 0 1 1 1 1 N2227-like protein Methyltransf_23 PF13489.6 KKK26933.1 - 0.047 13.5 0.0 0.087 12.7 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 KKK26933.1 - 0.051 14.3 0.0 0.24 12.2 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 KKK26933.1 - 0.069 13.8 0.0 0.21 12.2 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Sulfotransfer_3 PF13469.6 KKK26934.1 - 0.00086 19.7 0.2 0.22 11.9 0.0 3.3 2 1 0 2 2 2 1 Sulfotransferase family AAA_2 PF07724.14 KKK26935.1 - 7.7e-46 156.3 0.0 1.9e-44 151.8 0.0 2.8 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 KKK26935.1 - 4.7e-31 106.8 3.8 4.7e-31 106.8 3.8 3.4 3 0 0 3 3 3 1 AAA lid domain AAA PF00004.29 KKK26935.1 - 3.2e-27 95.6 0.0 3.8e-15 56.5 0.0 3.1 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 KKK26935.1 - 8.4e-25 86.6 0.4 3e-24 84.9 0.4 2.1 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 KKK26935.1 - 3.5e-15 56.2 0.0 2.2e-09 37.4 0.0 3.1 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KKK26935.1 - 2.1e-13 50.7 0.0 2.8e-05 24.4 0.0 4.4 2 1 1 3 3 3 2 AAA domain AAA_16 PF13191.6 KKK26935.1 - 2e-12 47.8 12.8 1.4e-06 28.8 0.1 5.8 4 2 1 6 6 5 2 AAA ATPase domain Sigma54_activat PF00158.26 KKK26935.1 - 1.3e-08 34.7 0.0 2.5e-05 24.1 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain Clp_N PF02861.20 KKK26935.1 - 6.2e-07 29.4 3.0 0.00043 20.4 0.1 4.4 4 0 0 4 4 3 1 Clp amino terminal domain, pathogenicity island component IstB_IS21 PF01695.17 KKK26935.1 - 1.6e-06 28.0 0.0 0.084 12.6 0.0 3.1 3 0 0 3 3 2 2 IstB-like ATP binding protein AAA_18 PF13238.6 KKK26935.1 - 1.7e-06 28.6 0.2 0.078 13.5 0.0 3.9 3 0 0 3 3 2 2 AAA domain AAA_14 PF13173.6 KKK26935.1 - 1.7e-06 28.1 0.0 0.12 12.5 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA_7 PF12775.7 KKK26935.1 - 4e-06 26.5 0.0 0.016 14.8 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region Mg_chelatase PF01078.21 KKK26935.1 - 5.6e-06 25.9 0.5 0.19 11.1 0.1 4.2 3 1 0 3 3 3 1 Magnesium chelatase, subunit ChlI TniB PF05621.11 KKK26935.1 - 2.1e-05 24.0 0.2 0.29 10.5 0.0 4.8 4 2 0 4 4 3 1 Bacterial TniB protein AAA_33 PF13671.6 KKK26935.1 - 2.2e-05 24.7 0.3 0.28 11.3 0.0 3.5 3 0 0 3 3 3 2 AAA domain RNA_helicase PF00910.22 KKK26935.1 - 5.5e-05 23.5 0.0 0.5 10.8 0.0 2.7 2 0 0 2 2 2 2 RNA helicase AAA_30 PF13604.6 KKK26935.1 - 0.0001 22.1 0.0 0.95 9.1 0.0 3.4 3 1 0 3 3 2 2 AAA domain RuvB_N PF05496.12 KKK26935.1 - 0.00016 21.5 1.0 1.9 8.2 0.5 4.4 3 1 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_24 PF13479.6 KKK26935.1 - 0.00022 21.0 0.0 0.25 11.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 KKK26935.1 - 0.00028 20.9 0.0 0.3 11.1 0.0 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE RsgA_GTPase PF03193.16 KKK26935.1 - 0.00029 20.8 0.2 0.4 10.6 0.0 3.1 3 0 0 3 3 3 1 RsgA GTPase AAA_28 PF13521.6 KKK26935.1 - 0.00041 20.6 4.5 0.64 10.2 0.0 3.9 3 1 1 4 4 3 2 AAA domain ABC_tran PF00005.27 KKK26935.1 - 0.0005 20.6 3.8 0.67 10.5 0.0 3.8 4 0 0 4 4 3 1 ABC transporter ATPase_2 PF01637.18 KKK26935.1 - 0.00052 20.0 10.2 0.11 12.3 0.3 4.8 5 1 0 5 5 3 1 ATPase domain predominantly from Archaea AAA_3 PF07726.11 KKK26935.1 - 0.00065 19.6 0.0 1.9 8.3 0.0 3.3 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 KKK26935.1 - 0.0016 18.8 0.0 0.49 10.7 0.0 3.3 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 KKK26935.1 - 0.0018 17.4 0.0 0.015 14.3 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_29 PF13555.6 KKK26935.1 - 0.002 17.8 0.0 1.9 8.3 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain Roc PF08477.13 KKK26935.1 - 0.0021 18.3 0.0 0.93 9.7 0.0 2.8 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase NACHT PF05729.12 KKK26935.1 - 0.0079 16.1 0.0 0.45 10.4 0.0 2.5 2 0 0 2 2 2 1 NACHT domain Zeta_toxin PF06414.12 KKK26935.1 - 0.0082 15.4 0.2 0.89 8.8 0.0 2.9 3 0 0 3 3 2 1 Zeta toxin AAA_25 PF13481.6 KKK26935.1 - 0.0095 15.5 0.2 2 8.0 0.0 3.1 2 1 0 2 2 2 1 AAA domain NTPase_1 PF03266.15 KKK26935.1 - 0.011 15.7 0.0 0.31 10.9 0.0 2.9 3 0 0 3 3 2 0 NTPase ResIII PF04851.15 KKK26935.1 - 0.018 15.0 0.0 3.7 7.5 0.0 3.6 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit Torsin PF06309.11 KKK26935.1 - 0.028 14.5 0.0 0.097 12.8 0.0 1.8 2 0 0 2 2 1 0 Torsin SRP54 PF00448.22 KKK26935.1 - 0.034 13.8 0.0 8.3 6.0 0.0 2.8 3 0 0 3 3 2 0 SRP54-type protein, GTPase domain AAA_15 PF13175.6 KKK26935.1 - 0.037 13.8 0.6 34 4.0 0.0 3.4 3 0 0 3 3 3 0 AAA ATPase domain Rad17 PF03215.15 KKK26935.1 - 0.059 13.3 0.0 12 5.7 0.0 2.9 2 1 0 3 3 2 0 Rad17 P-loop domain ATP_bind_1 PF03029.17 KKK26935.1 - 0.11 12.3 0.1 21 4.8 0.0 3.1 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein AAA_23 PF13476.6 KKK26935.1 - 0.22 12.0 0.0 0.22 12.0 0.0 4.6 4 2 0 5 5 2 0 AAA domain MPS2 PF17060.5 KKK26935.1 - 0.59 9.3 9.9 0.015 14.6 2.7 1.9 2 0 0 2 2 2 0 Monopolar spindle protein 2 DHR10 PF18595.1 KKK26935.1 - 0.73 9.9 19.4 1.6 8.8 13.8 3.1 2 1 0 2 2 1 0 Designed helical repeat protein 10 domain SbcD_C PF12320.8 KKK26935.1 - 3.1 8.1 9.7 21 5.5 0.3 3.6 3 0 0 3 3 2 0 Type 5 capsule protein repressor C-terminal domain V_ATPase_I PF01496.19 KKK26935.1 - 3.5 5.4 9.5 0.26 9.2 4.9 1.4 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Macoilin PF09726.9 KKK26935.1 - 9.6 4.6 10.8 19 3.6 10.8 1.4 1 0 0 1 1 1 0 Macoilin family Prefoldin_2 PF01920.20 KKK26936.1 - 2.3e-23 82.2 4.1 2.8e-23 81.9 4.1 1.1 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin PF02996.17 KKK26936.1 - 0.0087 16.0 4.7 0.015 15.2 0.3 2.2 1 1 1 2 2 2 1 Prefoldin subunit GPS2_interact PF15784.5 KKK26936.1 - 0.072 13.5 0.1 0.072 13.5 0.1 2.3 2 1 0 2 2 2 0 G-protein pathway suppressor 2-interacting domain Oxidored_nitro PF00148.19 KKK26936.1 - 0.098 11.4 0.0 0.14 10.8 0.0 1.3 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase DUF1664 PF07889.12 KKK26936.1 - 0.22 11.6 1.0 1.6 8.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) PEP-utilisers_N PF05524.13 KKK26936.1 - 0.24 11.6 0.1 0.24 11.6 0.1 2.2 1 1 1 2 2 2 0 PEP-utilising enzyme, N-terminal DivIC PF04977.15 KKK26936.1 - 0.96 9.3 11.0 6.3 6.7 4.6 2.3 2 0 0 2 2 2 0 Septum formation initiator Spc7 PF08317.11 KKK26936.1 - 4.3 6.1 13.6 5.8 5.7 0.2 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein zf-CpG_bind_C PF12269.8 KKK26936.1 - 8.3 6.1 7.3 7.7 6.2 4.3 1.9 1 1 1 2 2 2 0 CpG binding protein zinc finger C terminal domain ATG27 PF09451.10 KKK26937.1 - 2.7e-89 299.5 0.0 3.2e-89 299.3 0.0 1.0 1 0 0 1 1 1 1 Autophagy-related protein 27 CIMR PF00878.18 KKK26937.1 - 5.7e-07 29.7 0.0 3.5e-05 23.9 0.0 2.5 3 0 0 3 3 3 1 Cation-independent mannose-6-phosphate receptor repeat Tubulin_3 PF14881.6 KKK26938.1 - 8.3e-85 283.0 0.0 1.2e-84 282.5 0.0 1.3 1 0 0 1 1 1 1 Tubulin domain Misat_Tub_SegII PF10644.9 KKK26938.1 - 3.7e-41 140.2 0.0 1.7e-40 138.0 0.0 2.2 3 0 0 3 3 3 1 Misato Segment II tubulin-like domain Tubulin PF00091.25 KKK26938.1 - 0.0041 17.3 0.0 3.2 7.9 0.0 2.6 2 1 0 2 2 2 2 Tubulin/FtsZ family, GTPase domain GP3_package PF16677.5 KKK26939.1 - 0.073 13.2 0.8 0.19 11.9 0.1 2.0 2 0 0 2 2 2 0 DNA-packaging protein gp3 Thg1C PF14413.6 KKK26939.1 - 1.6 8.9 5.4 5 7.3 0.9 2.6 2 0 0 2 2 2 0 Thg1 C terminal domain Med30 PF11315.8 KKK26939.1 - 5.5 7.2 9.1 1.8 8.8 1.5 2.6 2 0 0 2 2 2 0 Mediator complex subunit 30 HSP70 PF00012.20 KKK26940.1 - 4.2e-60 203.6 3.0 4.8e-58 196.8 0.0 3.1 3 0 0 3 3 3 2 Hsp70 protein DUF2201_N PF13203.6 KKK26940.1 - 0.23 11.0 5.2 0.48 10.0 5.2 1.5 1 0 0 1 1 1 0 Putative metallopeptidase domain Mnd1 PF03962.15 KKK26940.1 - 0.47 10.8 1.9 4.3 7.7 0.3 3.0 3 0 0 3 3 3 0 Mnd1 HTH domain SlyX PF04102.12 KKK26940.1 - 4.9 7.9 7.7 0.89 10.2 0.5 3.4 2 1 1 3 3 3 0 SlyX SNF2_N PF00176.23 KKK26942.1 - 1.4e-57 195.0 0.0 2.2e-57 194.4 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KKK26942.1 - 5.1e-15 55.8 0.0 1.6e-14 54.1 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KKK26942.1 - 9.9e-09 35.4 0.0 2.3e-08 34.2 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF5473 PF17567.2 KKK26942.1 - 0.04 14.2 6.0 3 8.2 1.1 2.8 2 0 0 2 2 2 0 Family of unknown function (DUF5473) Ribosomal_60s PF00428.19 KKK26942.1 - 0.36 11.5 4.3 1.2 9.8 4.3 1.9 1 0 0 1 1 1 0 60s Acidic ribosomal protein WRNPLPNID PF15017.6 KKK26942.1 - 8.6 7.3 10.0 3.3 8.7 3.7 3.0 2 0 0 2 2 2 0 Putative WW-binding domain and destruction box DUF2347 PF09804.9 KKK26943.1 - 1e-105 353.4 0.0 2.1e-105 352.4 0.0 1.5 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2347) DUF4484 PF14831.6 KKK26943.1 - 5.3e-63 212.9 0.0 8.5e-63 212.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4484) Avl9 PF09794.9 KKK26943.1 - 0.0035 16.1 0.0 2 7.0 0.0 2.4 2 1 0 2 2 2 2 Transport protein Avl9 Afi1 PF07792.12 KKK26943.1 - 1.2 9.6 4.2 14 6.1 0.0 3.2 4 0 0 4 4 4 0 Docking domain of Afi1 for Arf3 in vesicle trafficking HNF-1_N PF04814.13 KKK26943.1 - 1.4 9.5 4.3 0.22 12.1 0.5 1.5 2 0 0 2 2 2 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus EBP PF05241.12 KKK26944.1 - 1.1e-47 161.8 6.8 1.2e-47 161.6 6.8 1.0 1 0 0 1 1 1 1 Emopamil binding protein YMF19 PF02326.15 KKK26944.1 - 0.28 12.0 3.3 3.6 8.4 0.2 2.2 2 0 0 2 2 2 0 Plant ATP synthase F0 AA_permease_2 PF13520.6 KKK26945.1 - 6.8e-41 140.5 49.5 8.4e-41 140.2 49.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KKK26945.1 - 2.1e-22 79.4 38.3 2.9e-22 78.9 38.3 1.0 1 0 0 1 1 1 1 Amino acid permease Phospholamban PF04272.14 KKK26945.1 - 1.6 8.2 0.0 1.6 8.2 0.0 4.1 4 0 0 4 4 4 0 Phospholamban EMC3_TMCO1 PF01956.16 KKK26946.1 - 1.4 8.6 6.6 8.2 6.1 0.8 2.6 2 1 1 3 3 3 0 Integral membrane protein EMC3/TMCO1-like DASH_Dad1 PF08649.10 KKK26947.1 - 7.1e-26 90.2 4.6 1.2e-25 89.4 4.6 1.4 1 0 0 1 1 1 1 DASH complex subunit Dad1 DASH_Dad4 PF08650.10 KKK26947.1 - 0.01 15.8 0.2 0.016 15.2 0.2 1.2 1 0 0 1 1 1 0 DASH complex subunit Dad4 ERG4_ERG24 PF01222.17 KKK26948.1 - 4.2e-134 447.5 18.1 4.9e-134 447.3 18.1 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Fungal_trans PF04082.18 KKK26949.1 - 8.2e-15 54.5 0.3 2.6e-14 52.9 0.3 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK26949.1 - 1.1e-08 35.1 6.8 2e-08 34.2 6.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3712 PF12505.8 KKK26950.1 - 8.6e-32 110.0 0.1 3.2e-31 108.2 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3712) vATP-synt_AC39 PF01992.16 KKK26950.1 - 0.2 11.1 1.2 1.1 8.6 0.8 2.5 2 1 0 2 2 2 0 ATP synthase (C/AC39) subunit DUF5510 PF17629.2 KKK26951.1 - 0.0098 15.8 7.0 0.0098 15.8 7.0 2.9 3 0 0 3 3 3 2 Family of unknown function (DUF5510) UPRTase PF14681.6 KKK26951.1 - 0.12 11.8 0.0 0.24 10.8 0.0 1.5 2 0 0 2 2 2 0 Uracil phosphoribosyltransferase MFS_1 PF07690.16 KKK26953.1 - 7.2e-45 153.4 43.9 9.7e-45 153.0 43.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KKK26953.1 - 1.1e-09 37.7 19.3 3.7e-09 35.9 19.4 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter AMP-binding PF00501.28 KKK26953.1 - 1.1e-09 37.4 0.1 2.2e-09 36.5 0.1 1.4 1 0 0 1 1 1 1 AMP-binding enzyme MFS_4 PF06779.14 KKK26953.1 - 1.2e-06 28.1 8.8 1.2e-06 28.1 8.8 2.3 3 0 0 3 3 3 1 Uncharacterised MFS-type transporter YbfB TRI12 PF06609.13 KKK26953.1 - 6.7e-06 24.8 4.1 1.1e-05 24.2 4.1 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) AMP-binding_C PF13193.6 KKK26953.1 - 0.00079 20.3 0.6 0.076 14.0 0.1 2.6 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain OATP PF03137.20 KKK26953.1 - 1.3 7.2 15.5 0.095 11.0 6.0 3.1 2 1 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family RTA1 PF04479.13 KKK26954.1 - 1.5e-67 227.2 7.5 2e-67 226.8 7.5 1.2 1 0 0 1 1 1 1 RTA1 like protein Zn_clus PF00172.18 KKK26955.1 - 3.1e-08 33.6 10.6 7.7e-08 32.3 10.6 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2 PF00096.26 KKK26955.1 - 0.0097 16.3 1.5 0.041 14.4 1.5 2.2 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KKK26955.1 - 0.13 13.2 1.7 0.74 10.8 1.7 2.4 1 0 0 1 1 1 0 C2H2-type zinc finger Opy2 PF09463.10 KKK26955.1 - 4.8 7.6 8.4 16 5.9 8.3 2.0 1 1 0 1 1 1 0 Opy2 protein Tri3 PF07428.11 KKK26956.1 - 9.4e-07 28.1 0.0 0.0049 15.8 0.0 2.1 2 0 0 2 2 2 2 15-O-acetyltransferase Tri3 Condensation PF00668.20 KKK26956.1 - 0.00048 18.9 0.0 0.2 10.3 0.0 2.1 2 0 0 2 2 2 2 Condensation domain ParG PF09274.10 KKK26956.1 - 0.18 11.9 0.0 0.46 10.6 0.0 1.6 1 0 0 1 1 1 0 ParG Ank_2 PF12796.7 KKK26957.1 - 3.5e-37 126.8 5.7 8.1e-14 52.0 0.0 8.2 6 2 1 7 7 7 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KKK26957.1 - 1.1e-28 99.3 13.6 1.3e-06 28.8 0.0 10.0 7 3 5 12 12 12 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 KKK26957.1 - 3.5e-28 97.3 7.0 0.0012 19.1 0.1 9.2 9 0 0 9 9 9 5 Ankyrin repeats (many copies) Ank PF00023.30 KKK26957.1 - 3.4e-22 77.8 14.9 0.00091 19.6 0.0 10.1 10 0 0 10 10 10 5 Ankyrin repeat Ank_3 PF13606.6 KKK26957.1 - 1.5e-21 74.1 8.1 0.0054 17.1 0.0 10.6 12 0 0 12 12 12 3 Ankyrin repeat Mpv17_PMP22 PF04117.12 KKK26958.1 - 5.3e-16 58.6 0.2 5.3e-16 58.6 0.2 2.2 2 0 0 2 2 2 1 Mpv17 / PMP22 family MFS_1 PF07690.16 KKK26959.1 - 1.6e-37 129.2 48.0 1.6e-37 129.2 48.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KKK26959.1 - 2.1e-09 36.7 11.9 2.1e-09 36.7 11.9 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter Ribosomal_L29 PF00831.23 KKK26960.1 - 6.6e-20 70.8 0.4 6.6e-20 70.8 0.4 1.9 2 0 0 2 2 2 1 Ribosomal L29 protein Med16 PF11635.8 KKK26961.1 - 8.5e-213 708.4 0.0 1.3e-109 367.2 0.0 2.0 1 1 1 2 2 2 2 Mediator complex subunit 16 ANAPC4_WD40 PF12894.7 KKK26961.1 - 8.1e-06 26.1 0.1 0.1 12.9 0.0 3.4 3 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain HAD_2 PF13419.6 KKK26962.1 - 3.3e-10 40.3 0.0 5e-07 30.0 0.0 2.1 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KKK26962.1 - 2.3e-06 28.0 0.0 0.0042 17.4 0.0 2.2 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KKK26962.1 - 0.00028 20.9 0.0 0.00048 20.1 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like SIR2 PF02146.17 KKK26963.1 - 8.2e-25 87.7 0.4 6.7e-24 84.8 0.0 2.5 2 1 0 2 2 2 1 Sir2 family ACP_PD PF04336.12 KKK26963.1 - 0.036 14.5 0.0 0.069 13.6 0.0 1.4 1 0 0 1 1 1 0 Acyl carrier protein phosphodiesterase Zn-ribbon_8 PF09723.10 KKK26963.1 - 0.78 9.9 4.5 0.69 10.1 1.8 2.3 3 0 0 3 3 3 0 Zinc ribbon domain Ter PF05472.11 KKK26964.1 - 0.017 14.1 0.0 0.024 13.7 0.0 1.2 1 0 0 1 1 1 0 DNA replication terminus site-binding protein (Ter protein) Osmo_CC PF08946.10 KKK26964.1 - 0.49 10.7 2.0 0.54 10.6 0.1 2.1 3 0 0 3 3 3 0 Osmosensory transporter coiled coil GN3L_Grn1 PF08701.11 KKK26965.1 - 2.5e-22 78.8 17.4 2.5e-22 78.8 17.4 2.5 4 0 0 4 4 4 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.23 KKK26965.1 - 6.4e-18 64.9 0.1 6.4e-14 52.0 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KKK26965.1 - 1e-06 28.7 0.0 2.3e-05 24.4 0.0 2.2 1 1 0 1 1 1 1 RsgA GTPase FeoB_N PF02421.18 KKK26965.1 - 1.2e-05 24.9 0.1 9.3e-05 22.0 0.1 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 KKK26965.1 - 3.9e-05 23.8 4.2 0.34 10.9 0.1 4.0 3 2 2 5 5 5 2 Dynamin family GTP_EFTU PF00009.27 KKK26965.1 - 0.00021 20.9 2.5 0.32 10.5 0.0 3.0 3 0 0 3 3 2 2 Elongation factor Tu GTP binding domain AAA_18 PF13238.6 KKK26965.1 - 0.0017 18.9 4.0 0.079 13.5 0.0 2.9 3 0 0 3 3 3 1 AAA domain AIG1 PF04548.16 KKK26965.1 - 0.008 15.5 0.5 0.61 9.4 0.0 2.9 3 0 0 3 3 3 1 AIG1 family MeaB PF03308.16 KKK26965.1 - 0.028 13.4 0.1 0.028 13.4 0.1 2.0 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB cobW PF02492.19 KKK26965.1 - 0.041 13.5 0.0 0.61 9.7 0.0 2.5 2 1 1 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain Roc PF08477.13 KKK26965.1 - 0.074 13.3 0.0 11 6.3 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase BUD22 PF09073.10 KKK26965.1 - 2.1 7.6 25.1 3.6 6.8 25.1 1.3 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 KKK26965.1 - 9.3 4.3 34.3 14 3.7 34.3 1.2 1 0 0 1 1 1 0 Nop14-like family CBFD_NFYB_HMF PF00808.23 KKK26966.1 - 0.00032 20.9 0.0 0.00058 20.1 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KKK26966.1 - 0.24 11.7 2.8 0.92 9.9 0.0 2.5 2 0 0 2 2 2 0 Core histone H2A/H2B/H3/H4 Drc1-Sld2 PF11719.8 KKK26966.1 - 1.9 8.0 19.7 2.2 7.7 19.7 1.3 1 0 0 1 1 1 0 DNA replication and checkpoint protein TFIIA PF03153.13 KKK26966.1 - 4.8 7.1 25.0 8.2 6.3 25.0 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit adh_short PF00106.25 KKK26967.1 - 2.9e-16 59.5 0.0 3.2e-16 59.4 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KKK26967.1 - 2.3e-11 43.7 0.0 2.6e-11 43.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KKK26967.1 - 2.2e-06 27.7 0.0 2.4e-06 27.6 0.0 1.0 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KKK26967.1 - 0.012 15.1 0.0 0.012 15.1 0.0 1.1 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KKK26967.1 - 0.028 13.6 0.0 0.029 13.5 0.0 1.0 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein TIR PF01582.20 KKK26967.1 - 0.18 11.6 0.0 0.21 11.4 0.0 1.3 1 1 0 1 1 1 0 TIR domain Methyltransf_2 PF00891.18 KKK26968.1 - 2.1e-20 72.9 0.0 3.1e-20 72.4 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_31 PF13847.6 KKK26968.1 - 0.00068 19.4 0.0 0.0013 18.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain HTH_AsnC-type PF13404.6 KKK26968.1 - 0.00087 19.1 0.0 0.0018 18.0 0.0 1.5 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain MTS PF05175.14 KKK26968.1 - 0.0058 16.2 0.0 0.013 15.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 KKK26968.1 - 0.012 16.4 0.0 0.031 15.0 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain HTH_28 PF13518.6 KKK26968.1 - 0.015 15.4 0.1 0.051 13.7 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain TetR_C_27 PF17935.1 KKK26968.1 - 0.073 13.1 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain HTH_24 PF13412.6 KKK26968.1 - 0.086 12.4 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Methyltransf_12 PF08242.12 KKK26968.1 - 0.17 12.6 0.0 0.35 11.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Pkinase PF00069.25 KKK26969.1 - 7.2e-40 137.0 0.1 8.3e-23 81.1 0.3 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KKK26969.1 - 4.9e-14 52.2 0.5 6e-10 38.8 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 KKK26969.1 - 0.065 12.0 2.1 0.053 12.3 0.2 1.7 1 1 1 2 2 2 0 Fungal protein kinase RIO1 PF01163.22 KKK26969.1 - 0.069 12.7 0.0 0.22 11.1 0.0 1.9 1 0 0 1 1 1 0 RIO1 family DNA_binding_1 PF01035.20 KKK26970.1 - 2e-24 85.5 0.0 2.5e-24 85.2 0.0 1.1 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain DUF4224 PF13986.6 KKK26970.1 - 0.039 13.8 0.0 0.53 10.2 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4224) Lipid_DES PF08557.10 KKK26971.1 - 0.046 13.2 0.0 2.2 7.8 0.0 2.7 2 0 0 2 2 2 0 Sphingolipid Delta4-desaturase (DES) MIF4G PF02854.19 KKK26972.1 - 8.2e-24 84.4 0.2 2.2e-23 83.0 0.2 1.8 1 0 0 1 1 1 1 MIF4G domain MA3 PF02847.17 KKK26972.1 - 1e-18 67.4 0.0 3.3e-18 65.7 0.0 1.9 2 0 0 2 2 2 1 MA3 domain Not3 PF04065.15 KKK26973.1 - 1.6e-88 296.1 18.4 2.3e-88 295.5 18.4 1.2 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.18 KKK26973.1 - 1.5e-45 154.5 12.3 3.2e-45 153.4 12.3 1.6 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family GbpC PF08363.10 KKK26973.1 - 0.028 13.9 0.2 0.18 11.3 0.0 2.1 1 1 1 2 2 2 0 Glucan-binding protein C DUF2373 PF10180.9 KKK26973.1 - 0.095 12.6 5.8 0.036 13.9 2.7 1.9 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2373) Cep57_MT_bd PF06657.13 KKK26973.1 - 0.11 13.0 5.2 1.2 9.6 0.2 2.7 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 DUF1192 PF06698.11 KKK26973.1 - 0.11 12.5 2.2 0.26 11.4 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) Snapin_Pallidin PF14712.6 KKK26973.1 - 0.28 11.6 5.2 0.86 10.1 1.0 2.6 2 0 0 2 2 2 0 Snapin/Pallidin GIT_CC PF16559.5 KKK26973.1 - 0.33 10.8 2.2 3.5 7.6 0.4 2.5 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor RPW8 PF05659.11 KKK26973.1 - 1.4 8.6 9.3 0.18 11.5 4.2 2.1 2 0 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Swi5 PF07061.11 KKK26973.1 - 2.8 8.1 8.5 5.8 7.1 1.7 3.2 2 1 1 3 3 3 0 Swi5 Syntaxin_2 PF14523.6 KKK26973.1 - 5.9 7.3 12.3 0.045 14.1 1.9 2.7 3 0 0 3 3 3 0 Syntaxin-like protein DUF1690 PF07956.11 KKK26973.1 - 6.5 7.2 12.8 5.8 7.3 6.3 2.4 1 1 1 2 2 2 0 Protein of Unknown function (DUF1690) Tyr_Deacylase PF02580.16 KKK26974.1 - 9.3e-45 152.7 0.0 1.5e-44 152.0 0.0 1.2 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase Pro_isomerase PF00160.21 KKK26975.1 - 4.3e-50 170.1 0.4 8.3e-50 169.1 0.4 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_2 PF07719.17 KKK26975.1 - 4e-07 29.6 4.6 3.8e-05 23.5 0.1 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 KKK26975.1 - 1.9e-06 27.4 4.6 1.2e-05 24.9 0.1 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 KKK26975.1 - 0.0001 22.5 3.3 0.00019 21.7 1.9 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 KKK26975.1 - 0.00036 20.5 3.3 0.015 15.5 0.1 3.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_9 PF13371.6 KKK26975.1 - 0.004 17.3 1.0 0.064 13.4 0.7 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 KKK26975.1 - 0.05 14.5 2.0 0.12 13.3 0.9 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 KKK26975.1 - 0.061 13.0 4.2 3.3 7.5 0.3 3.3 2 1 1 3 3 3 0 TPR repeat Ribonuclease PF00545.20 KKK26975.1 - 0.064 14.0 0.0 0.14 13.0 0.0 1.5 1 0 0 1 1 1 0 ribonuclease TPR_16 PF13432.6 KKK26975.1 - 0.083 13.6 3.4 1 10.1 2.9 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 KKK26975.1 - 0.2 12.4 0.9 2 9.2 0.2 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 KKK26975.1 - 0.27 11.8 2.8 0.65 10.6 2.8 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat Gly_transf_sug PF04488.15 KKK26976.1 - 6.3e-21 74.8 0.1 1.1e-20 74.0 0.1 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 KKK26976.1 - 0.016 14.6 0.1 0.026 13.9 0.1 1.3 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein Coatomer_E PF04733.14 KKK26978.1 - 3.2e-16 59.6 0.0 3.5e-16 59.5 0.0 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_12 PF13424.6 KKK26978.1 - 1.5e-05 25.2 0.4 0.001 19.3 0.2 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 KKK26978.1 - 0.0012 19.4 0.1 0.26 12.0 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KKK26978.1 - 0.011 16.0 0.0 0.46 10.8 0.0 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 KKK26978.1 - 0.027 14.8 0.1 0.19 12.2 0.0 2.3 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_20 PF14561.6 KKK26978.1 - 0.056 13.8 1.6 0.13 12.6 0.5 2.0 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 KKK26978.1 - 0.089 13.3 2.5 0.31 11.6 1.0 2.3 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_4 PF07721.14 KKK26978.1 - 0.14 12.9 0.1 0.14 12.9 0.1 3.3 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 KKK26978.1 - 0.72 10.8 5.3 9.6 7.3 0.4 3.1 1 1 2 3 3 3 0 Tetratricopeptide repeat PI-PLC-X PF00388.19 KKK26979.1 - 2.5e-60 202.3 0.0 4.4e-60 201.5 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 KKK26979.1 - 7.5e-44 148.7 0.4 7.4e-42 142.3 0.1 2.5 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, Y domain GDPD PF03009.17 KKK26979.1 - 0.0063 16.3 0.0 0.023 14.4 0.0 1.8 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family EF-hand_1 PF00036.32 KKK26979.1 - 0.012 15.1 0.6 0.062 12.9 0.1 2.4 2 0 0 2 2 2 0 EF hand EF-hand_like PF09279.11 KKK26979.1 - 0.013 15.9 0.1 0.03 14.8 0.1 1.6 1 0 0 1 1 1 0 Phosphoinositide-specific phospholipase C, efhand-like Colicin_Pyocin PF01320.18 KKK26979.1 - 0.17 12.0 0.1 0.48 10.6 0.1 1.8 1 0 0 1 1 1 0 Colicin immunity protein / pyocin immunity protein EF-hand_7 PF13499.6 KKK26979.1 - 0.31 11.5 2.4 1.2 9.6 2.4 2.1 1 1 0 1 1 1 0 EF-hand domain pair SAP25 PF15476.6 KKK26980.1 - 0.031 14.0 0.0 0.051 13.2 0.0 1.3 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP25 SPAR_C PF11881.8 KKK26980.1 - 0.051 13.5 0.1 0.079 12.9 0.1 1.2 1 0 0 1 1 1 0 C-terminal domain of SPAR protein Y_phosphatase2 PF03162.13 KKK26981.1 - 6.8e-49 165.6 0.0 8.6e-49 165.3 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 KKK26981.1 - 8.7e-10 39.0 0.0 1.3e-09 38.4 0.0 1.4 1 1 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 KKK26981.1 - 0.00039 20.2 0.0 0.00051 19.9 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KKK26981.1 - 0.0051 16.4 0.0 0.0069 16.0 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 KKK26981.1 - 0.0057 16.8 0.0 0.0091 16.1 0.0 1.2 1 0 0 1 1 1 1 Inositol hexakisphosphate CDKN3 PF05706.12 KKK26981.1 - 0.082 12.6 0.1 0.13 11.9 0.1 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Peptidase_M24 PF00557.24 KKK26982.1 - 1.6e-44 152.1 0.1 2.1e-44 151.7 0.1 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 PGA2 PF07543.12 KKK26982.1 - 0.58 10.1 7.9 1.3 9.0 7.9 1.5 1 0 0 1 1 1 0 Protein trafficking PGA2 CCDC106 PF15794.5 KKK26982.1 - 2.4 7.8 5.6 4 7.1 5.6 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 GEN1_C PF18380.1 KKK26982.1 - 2.7 8.9 6.1 6.9 7.6 6.1 1.6 1 0 0 1 1 1 0 Holliday junction resolvase Gen1 C-terminal domain FA_desaturase PF00487.24 KKK26983.1 - 6.4e-25 88.4 15.4 8.5e-25 88.0 15.4 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.10 KKK26983.1 - 3.7e-18 64.7 0.2 6.1e-18 64.0 0.2 1.4 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) Rad52_Rad22 PF04098.15 KKK26984.1 - 2.4e-58 196.4 0.0 3.5e-58 195.9 0.0 1.2 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein Aa_trans PF01490.18 KKK26985.1 - 1e-74 251.7 32.4 1.2e-74 251.4 32.4 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Motile_Sperm PF00635.26 KKK26986.1 - 2.6e-23 81.9 0.6 5.8e-23 80.8 0.5 1.6 1 1 1 2 2 2 1 MSP (Major sperm protein) domain ASH PF15780.5 KKK26986.1 - 0.023 14.9 0.4 0.69 10.2 0.0 2.5 3 0 0 3 3 3 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin UBA PF00627.31 KKK26987.1 - 3.3e-06 26.9 0.0 6.6e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain UBX PF00789.20 KKK26987.1 - 0.0011 19.1 0.3 0.0067 16.6 0.0 2.4 3 0 0 3 3 3 1 UBX domain CDC27 PF09507.10 KKK26987.1 - 0.013 15.0 22.9 0.014 14.8 22.9 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 zf-C2H2_2 PF12756.7 KKK26987.1 - 0.037 14.4 0.3 0.083 13.2 0.3 1.6 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) Utp11 PF03998.13 KKK26987.1 - 0.091 12.7 22.2 0.12 12.2 22.2 1.1 1 0 0 1 1 1 0 Utp11 protein GATA PF00320.27 KKK26987.1 - 0.16 11.6 0.0 0.28 10.8 0.0 1.4 1 0 0 1 1 1 0 GATA zinc finger zf-C2HE PF16278.5 KKK26987.1 - 0.28 11.6 0.1 0.28 11.6 0.1 2.9 2 1 0 2 2 1 0 C2HE / C2H2 / C2HC zinc-binding finger CpXC PF14353.6 KKK26987.1 - 1.7 8.7 8.2 6.6 6.8 8.2 2.0 1 1 0 1 1 1 0 CpXC protein DUF4551 PF15087.6 KKK26987.1 - 2.2 7.0 10.6 2.7 6.7 10.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Rtf2 PF04641.12 KKK26987.1 - 3 7.1 20.3 5.1 6.4 20.3 1.4 1 0 0 1 1 1 0 Rtf2 RING-finger V_ATPase_I PF01496.19 KKK26987.1 - 3 5.6 6.8 3 5.6 6.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CENP-N PF05238.13 KKK26987.1 - 4.3 6.5 12.8 6 6.1 12.8 1.2 1 0 0 1 1 1 0 Kinetochore protein CHL4 like ArfGap PF01412.18 KKK26987.1 - 4.8 7.3 8.9 0.22 11.6 2.1 2.1 2 1 1 3 3 3 0 Putative GTPase activating protein for Arf SOBP PF15279.6 KKK26987.1 - 5.3 7.6 8.5 6.7 7.2 8.5 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein LMBR1 PF04791.16 KKK26987.1 - 6.1 5.6 5.1 6.3 5.6 5.1 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein GREB1 PF15782.5 KKK26987.1 - 7 3.6 10.2 7.9 3.5 10.2 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer FapA PF03961.13 KKK26987.1 - 7.5 5.0 15.5 11 4.5 15.5 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A ALMT PF11744.8 KKK26987.1 - 9.1 5.0 10.3 12 4.6 10.3 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter SAP PF02037.27 KKK26989.1 - 1.9e-08 33.9 0.4 4.1e-08 32.8 0.0 1.8 2 0 0 2 2 2 1 SAP domain Ribosomal_S7e PF01251.18 KKK26989.1 - 0.069 12.9 0.0 0.15 11.8 0.0 1.5 2 0 0 2 2 2 0 Ribosomal protein S7e FMN_dh PF01070.18 KKK26990.1 - 3.5e-114 381.5 0.0 4.1e-114 381.2 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 KKK26990.1 - 1.6e-18 66.6 0.0 3.4e-18 65.5 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 KKK26990.1 - 4.6e-05 22.7 0.0 8.1e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase ThiG PF05690.14 KKK26990.1 - 0.0017 17.7 0.0 0.22 10.8 0.0 2.2 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG IMPDH PF00478.25 KKK26990.1 - 0.011 14.8 0.0 0.019 14.0 0.0 1.4 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 KKK26990.1 - 0.089 12.2 0.1 0.26 10.6 0.0 1.7 1 1 1 2 2 2 0 Nitronate monooxygenase TatD_DNase PF01026.21 KKK26991.1 - 2.3e-51 174.7 0.0 2.7e-51 174.4 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase Vfa1 PF08432.10 KKK26992.1 - 3.2e-60 203.5 18.7 3.6e-60 203.4 18.7 1.0 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 SAGA-Tad1 PF12767.7 KKK26992.1 - 0.0026 17.5 6.8 0.0027 17.5 6.8 1.1 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit SprA-related PF12118.8 KKK26992.1 - 0.024 13.8 9.3 0.029 13.5 9.3 1.1 1 0 0 1 1 1 0 SprA-related family NPR3 PF03666.13 KKK26992.1 - 0.1 11.3 11.7 0.12 11.1 11.7 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 RR_TM4-6 PF06459.12 KKK26992.1 - 0.11 12.4 14.7 0.15 11.9 14.7 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 AAA_15 PF13175.6 KKK26992.1 - 0.11 12.2 13.4 0.12 12.1 13.4 1.0 1 0 0 1 1 1 0 AAA ATPase domain SAPS PF04499.15 KKK26992.1 - 0.21 10.3 8.6 0.23 10.2 8.6 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein PPL5 PF18168.1 KKK26992.1 - 0.26 10.6 7.4 0.31 10.3 7.4 1.1 1 0 0 1 1 1 0 Prim-pol family 5 DUF913 PF06025.12 KKK26992.1 - 0.3 10.0 5.0 0.38 9.7 5.0 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF4407 PF14362.6 KKK26992.1 - 0.6 9.4 10.5 0.73 9.1 10.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) MMU163 PF17119.5 KKK26992.1 - 0.74 8.9 6.0 1 8.5 6.0 1.1 1 0 0 1 1 1 0 Mitochondrial protein up-regulated during meiosis GCD14 PF08704.10 KKK26992.1 - 0.8 9.3 5.4 1.1 8.9 5.4 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit HCMV_UL139 PF12507.8 KKK26992.1 - 0.86 10.0 10.7 1.9 8.9 10.5 1.7 1 1 0 1 1 1 0 Human Cytomegalovirus UL139 protein XRN_M PF17846.1 KKK26992.1 - 1 8.2 10.3 1.2 8.0 10.3 1.1 1 0 0 1 1 1 0 Xrn1 helical domain SLC12 PF03522.15 KKK26992.1 - 1.2 8.1 11.0 1.4 7.9 11.0 1.1 1 0 0 1 1 1 0 Solute carrier family 12 ATP11 PF06644.11 KKK26992.1 - 1.9 8.2 15.4 2.4 7.9 15.4 1.2 1 0 0 1 1 1 0 ATP11 protein DASH_Spc19 PF08287.11 KKK26992.1 - 2.1 8.2 22.3 4.2 7.3 22.3 1.5 1 1 0 1 1 1 0 Spc19 Hid1 PF12722.7 KKK26992.1 - 3.5 5.7 9.8 3.8 5.5 9.8 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein NARP1 PF12569.8 KKK26992.1 - 4.2 6.2 18.2 5 5.9 18.2 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Neur_chan_memb PF02932.16 KKK26992.1 - 4.3 7.3 6.0 4.8 7.2 6.0 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region MAP17 PF15807.5 KKK26992.1 - 4.4 7.6 11.0 8.1 6.7 11.0 1.6 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Presenilin PF01080.17 KKK26992.1 - 4.4 6.0 13.3 5.4 5.7 13.3 1.1 1 0 0 1 1 1 0 Presenilin FAM60A PF15396.6 KKK26992.1 - 6.1 6.8 16.5 6.1 6.8 12.8 2.0 2 0 0 2 2 2 0 Protein Family FAM60A TP53IP5 PF15331.6 KKK26992.1 - 7.7 6.6 12.6 10 6.2 12.6 1.2 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 CDC45 PF02724.14 KKK26992.1 - 9.1 4.4 20.5 11 4.2 20.5 1.0 1 0 0 1 1 1 0 CDC45-like protein 4HBT PF03061.22 KKK26993.1 - 0.041 14.2 0.1 4.5 7.7 0.1 2.5 2 0 0 2 2 2 0 Thioesterase superfamily Asp PF00026.23 KKK26994.1 - 5.8e-71 239.5 6.4 5.8e-71 239.5 6.4 1.8 2 0 0 2 2 2 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KKK26994.1 - 6.3e-15 55.8 10.3 1e-09 38.9 0.5 3.1 3 1 1 4 4 4 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KKK26994.1 - 2.3e-06 28.1 0.1 0.095 13.4 0.0 2.9 2 0 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 KKK26994.1 - 0.0066 17.0 0.0 7.6 7.2 0.0 2.9 2 1 0 2 2 2 2 gag-polyprotein putative aspartyl protease TAXi_C PF14541.6 KKK26994.1 - 0.016 15.0 0.0 0.14 11.9 0.0 2.2 2 0 0 2 2 2 0 Xylanase inhibitor C-terminal Pkinase PF00069.25 KKK26995.1 - 5.1e-24 85.1 0.0 1.4e-23 83.6 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK26995.1 - 3.5e-09 36.3 0.0 4.4e-08 32.7 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase DSPc PF00782.20 KKK26996.1 - 1.2e-24 86.6 0.0 1.6e-24 86.2 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 KKK26996.1 - 0.0014 18.9 0.0 0.0029 17.9 0.0 1.5 1 0 0 1 1 1 1 Rit1 DUSP-like domain Y_phosphatase PF00102.27 KKK26996.1 - 0.0029 17.2 0.0 0.0047 16.5 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase IBR PF01485.21 KKK26996.1 - 0.16 12.3 3.6 1.4 9.2 0.6 2.5 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain PTPlike_phytase PF14566.6 KKK26996.1 - 0.18 11.9 0.0 0.3 11.2 0.0 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate Peptidase_M24 PF00557.24 KKK26997.1 - 1.3e-19 70.8 0.0 1.5e-19 70.5 0.0 1.0 1 0 0 1 1 1 1 Metallopeptidase family M24 Methyltransf_31 PF13847.6 KKK26998.1 - 3.8e-12 46.3 0.0 3.7e-11 43.1 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KKK26998.1 - 2.4e-07 30.7 0.0 5e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKK26998.1 - 1.6e-06 28.7 0.2 1.6e-05 25.5 0.0 2.8 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.12 KKK26998.1 - 8.7e-05 23.1 0.1 0.001 19.6 0.1 3.0 1 1 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 KKK26998.1 - 0.0047 16.5 0.1 0.0091 15.6 0.1 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Cep3 PF16846.5 KKK26998.1 - 0.014 13.9 0.2 0.021 13.3 0.2 1.2 1 0 0 1 1 1 0 Centromere DNA-binding protein complex CBF3 subunit B Methyltransf_12 PF08242.12 KKK26998.1 - 0.026 15.3 0.0 0.14 12.9 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain MTS PF05175.14 KKK26998.1 - 0.2 11.2 0.0 0.39 10.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Herpes_UL32 PF06070.11 KKK26998.1 - 0.51 8.0 7.6 3.6 5.2 0.0 2.1 2 0 0 2 2 2 0 Herpesvirus large structural phosphoprotein UL32 Cytomega_TRL10 PF06084.11 KKK26998.1 - 3.5 7.6 9.6 7.1 6.6 0.2 2.5 2 0 0 2 2 2 0 Cytomegalovirus TRL10 protein DSPc PF00782.20 KKK26999.1 - 4.1e-23 81.7 0.0 8.6e-22 77.4 0.0 2.1 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Ribosomal_L5e PF17144.4 KKK27000.1 - 1.5e-10 41.3 6.9 1.8e-10 41.0 6.9 1.1 1 0 0 1 1 1 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Cript PF10235.9 KKK27001.1 - 2.4e-26 92.1 8.9 2.4e-26 92.1 8.9 1.8 1 1 1 2 2 2 1 Microtubule-associated protein CRIPT DZR PF12773.7 KKK27001.1 - 0.0075 16.3 14.8 0.014 15.4 8.5 2.6 1 1 1 2 2 2 2 Double zinc ribbon CEBP_ZZ PF16366.5 KKK27001.1 - 0.018 15.2 4.7 0.018 15.2 4.7 1.8 2 0 0 2 2 2 0 Cytoplasmic polyadenylation element-binding protein ZZ domain zinc_ribbon_15 PF17032.5 KKK27001.1 - 0.019 15.7 11.2 0.076 13.8 7.7 2.7 2 1 0 2 2 2 0 zinc-ribbon family DUF2321 PF10083.9 KKK27001.1 - 0.066 12.8 2.2 0.1 12.3 2.2 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2321) zinc_ribbon_2 PF13240.6 KKK27001.1 - 0.14 12.0 12.3 3.2 7.6 3.1 3.4 3 0 0 3 3 3 0 zinc-ribbon domain Prok-RING_4 PF14447.6 KKK27001.1 - 0.34 10.8 10.1 0.34 10.8 1.7 3.1 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 zf-HYPF PF07503.12 KKK27001.1 - 0.49 10.2 10.2 1.1 9.1 5.5 2.3 2 0 0 2 2 2 0 HypF finger DUF2039 PF10217.9 KKK27001.1 - 1.2 9.5 17.1 0.54 10.6 11.2 2.3 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) zf-C3HC4_3 PF13920.6 KKK27001.1 - 3.7 7.5 14.9 62 3.6 10.2 3.0 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-ribbon_3 PF13248.6 KKK27001.1 - 6 6.4 9.2 3 7.4 0.2 3.2 3 0 0 3 3 3 0 zinc-ribbon domain DUF1272 PF06906.11 KKK27001.1 - 7 6.8 13.9 16 5.7 9.1 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1272) MRP-L46 PF11788.8 KKK27002.1 - 9.4e-39 132.8 1.6 1.6e-38 132.1 1.6 1.4 1 0 0 1 1 1 1 39S mitochondrial ribosomal protein L46 NUDIX PF00293.28 KKK27002.1 - 0.032 14.3 0.0 0.068 13.2 0.0 1.5 1 0 0 1 1 1 0 NUDIX domain CAF1 PF04857.20 KKK27003.1 - 1.7e-74 250.9 0.0 2e-74 250.6 0.0 1.1 1 0 0 1 1 1 1 CAF1 family ribonuclease Acetyltransf_1 PF00583.25 KKK27005.1 - 3.3e-18 66.0 0.0 4.6e-18 65.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KKK27005.1 - 1.1e-11 45.0 0.0 1.6e-11 44.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KKK27005.1 - 1.4e-11 44.2 0.1 2.3e-11 43.5 0.1 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 KKK27005.1 - 1.5e-11 44.3 0.0 2.2e-11 43.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KKK27005.1 - 1.2e-07 32.5 0.0 1.6e-07 32.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 KKK27005.1 - 2.8e-06 27.1 0.0 4.1e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KKK27005.1 - 3.8e-06 27.0 0.0 7e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KKK27005.1 - 0.00035 20.7 0.0 0.00067 19.7 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase GNAT_acetyltran PF12746.7 KKK27005.1 - 0.019 14.5 0.0 0.036 13.6 0.0 1.4 1 0 0 1 1 1 0 GNAT acetyltransferase PanZ PF12568.8 KKK27005.1 - 0.073 12.8 0.1 0.1 12.3 0.1 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_13 PF13880.6 KKK27005.1 - 0.11 12.5 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase Acetyltransf_15 PF17013.5 KKK27005.1 - 0.13 11.7 0.0 0.26 10.7 0.0 1.6 1 1 0 1 1 1 0 Putative acetyl-transferase SpoIIIAH PF12685.7 KKK27006.1 - 0.16 11.7 0.2 0.32 10.8 0.2 1.4 1 0 0 1 1 1 0 SpoIIIAH-like protein Glyco_transf_90 PF05686.12 KKK27007.1 - 4.2e-29 101.7 0.5 5.4e-29 101.3 0.5 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 90 Scaffolding_pro PF11418.8 KKK27007.1 - 0.047 14.2 0.0 0.096 13.3 0.0 1.4 1 0 0 1 1 1 0 Phi29 scaffolding protein LCAT PF02450.15 KKK27008.1 - 7e-104 348.1 0.0 8.4e-104 347.8 0.0 1.1 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase HutD PF05962.11 KKK27008.1 - 0.0057 16.6 0.0 0.0099 15.9 0.0 1.3 1 0 0 1 1 1 1 HutD RasGAP PF00616.19 KKK27009.1 - 7.8e-60 202.1 0.5 1.7e-59 201.0 0.0 1.9 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 KKK27009.1 - 3.8e-31 108.0 5.5 3.8e-31 108.0 5.5 2.8 3 0 0 3 3 3 1 RasGAP C-terminus CRAL_TRIO PF00650.20 KKK27010.1 - 5.5e-38 130.2 0.0 1.1e-37 129.3 0.0 1.4 2 0 0 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KKK27010.1 - 9.2e-08 32.2 0.2 2.3e-07 30.9 0.2 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 KKK27010.1 - 0.0016 18.6 0.0 0.0028 17.8 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain TMF_DNA_bd PF12329.8 KKK27010.1 - 0.051 13.6 0.0 7.6 6.6 0.0 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Mis14 PF08641.12 KKK27011.1 - 3e-31 108.5 8.1 3e-31 108.5 8.1 2.5 3 1 1 4 4 2 1 Kinetochore protein Mis14 like Med17 PF10156.9 KKK27011.1 - 0.00069 18.4 3.5 0.00082 18.2 3.5 1.1 1 0 0 1 1 1 1 Subunit 17 of Mediator complex Myc_N PF01056.18 KKK27011.1 - 0.0038 17.2 5.7 0.0051 16.8 5.7 1.2 1 0 0 1 1 1 1 Myc amino-terminal region DUF4611 PF15387.6 KKK27011.1 - 0.013 15.7 22.7 0.021 15.0 11.9 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4611) CDC45 PF02724.14 KKK27011.1 - 0.036 12.4 19.2 0.046 12.0 19.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Mpp10 PF04006.12 KKK27011.1 - 0.037 12.5 18.3 0.05 12.0 18.3 1.1 1 0 0 1 1 1 0 Mpp10 protein BSP_II PF05432.11 KKK27011.1 - 0.042 13.5 13.8 0.055 13.2 13.8 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) PBP_sp32 PF07222.12 KKK27011.1 - 0.29 10.5 5.2 0.51 9.7 4.8 1.6 2 0 0 2 2 2 0 Proacrosin binding protein sp32 DUF913 PF06025.12 KKK27011.1 - 0.32 9.9 7.3 0.5 9.3 7.3 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Nop14 PF04147.12 KKK27011.1 - 0.38 8.9 18.8 0.49 8.6 18.8 1.2 1 0 0 1 1 1 0 Nop14-like family RR_TM4-6 PF06459.12 KKK27011.1 - 0.62 9.8 12.2 0.86 9.4 12.2 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 TFIIF_alpha PF05793.12 KKK27011.1 - 1.4 7.4 22.7 2 6.9 22.7 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Paf1 PF03985.13 KKK27011.1 - 1.6 7.6 17.0 2.3 7.1 17.0 1.2 1 0 0 1 1 1 0 Paf1 DUF1682 PF07946.14 KKK27011.1 - 1.8 7.7 7.2 3.1 6.9 7.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) DNA_pol_phi PF04931.13 KKK27011.1 - 1.8 6.5 19.7 2.2 6.3 19.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi RRN3 PF05327.11 KKK27011.1 - 2.8 6.4 11.9 3.5 6.1 11.9 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 SAPS PF04499.15 KKK27011.1 - 3.1 6.5 7.0 3.4 6.3 7.0 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Sporozoite_P67 PF05642.11 KKK27011.1 - 3.5 5.6 7.3 4.7 5.2 7.3 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Dicty_REP PF05086.12 KKK27011.1 - 4.4 5.2 6.2 6.4 4.6 6.2 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein ALMT PF11744.8 KKK27011.1 - 4.7 5.9 5.2 6 5.6 5.2 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Hid1 PF12722.7 KKK27011.1 - 4.7 5.2 8.1 5.9 4.9 8.1 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein COPI_C PF06957.11 KKK27011.1 - 8.7 5.0 10.3 12 4.6 10.3 1.2 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus Pes-10 PF07149.11 KKK27011.1 - 9.8 5.1 13.5 13 4.7 13.5 1.2 1 0 0 1 1 1 0 Pes-10 Pex24p PF06398.11 KKK27012.1 - 1.2e-05 24.5 1.4 1.8e-05 23.9 1.4 1.2 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Ribonuc_L-PSP PF01042.21 KKK27013.1 - 4.5e-16 59.0 0.0 5.8e-07 29.6 0.0 3.3 3 0 0 3 3 3 3 Endoribonuclease L-PSP Diphthami_syn_2 PF01902.17 KKK27013.1 - 2e-14 53.6 0.0 6.8e-05 22.5 0.0 4.1 3 1 1 4 4 4 3 Diphthamide synthase Myc_N PF01056.18 KKK27013.1 - 0.018 14.9 1.1 0.033 14.1 1.1 1.3 1 0 0 1 1 1 0 Myc amino-terminal region DUF4611 PF15387.6 KKK27013.1 - 0.19 11.9 2.7 0.55 10.5 2.7 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) zf-C2H2 PF00096.26 KKK27014.1 - 1.9e-12 46.9 11.8 2.1e-06 27.9 0.4 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KKK27014.1 - 6.3e-08 32.8 10.1 0.0021 18.7 0.3 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KKK27014.1 - 1.1e-07 31.9 10.4 7.5e-07 29.3 4.1 3.4 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KKK27014.1 - 3e-05 24.2 3.9 0.011 16.0 0.5 2.4 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KKK27014.1 - 3.3e-05 24.1 4.1 0.0074 16.6 0.3 2.7 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KKK27014.1 - 0.0001 22.2 8.7 0.0054 16.7 0.5 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf_C2H2_ZHX PF18387.1 KKK27014.1 - 0.00032 20.3 3.5 0.14 11.9 0.2 2.8 1 1 1 2 2 2 2 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_3rep PF18868.1 KKK27014.1 - 0.15 12.8 2.8 3.3 8.4 0.4 2.8 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-BED PF02892.15 KKK27014.1 - 0.21 11.7 6.0 0.078 13.0 2.0 2.1 1 1 1 2 2 2 0 BED zinc finger zf-UBP PF02148.19 KKK27014.1 - 0.4 11.0 1.8 5.8 7.3 2.3 2.2 1 1 1 2 2 2 0 Zn-finger in ubiquitin-hydrolases and other protein zf-C2H2_11 PF16622.5 KKK27014.1 - 0.6 9.9 7.8 9.9 6.0 0.0 2.6 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2H2_2 PF12756.7 KKK27014.1 - 0.67 10.3 3.5 11 6.4 0.4 2.4 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-LYAR PF08790.11 KKK27014.1 - 0.74 9.8 4.7 17 5.4 0.1 3.0 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger zf-C2HE PF16278.5 KKK27014.1 - 0.84 10.1 6.9 94 3.6 6.9 2.6 1 1 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger MOSC PF03473.17 KKK27015.1 - 1.8e-32 112.1 0.0 3e-32 111.4 0.0 1.4 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 KKK27015.1 - 1.7e-30 105.4 0.0 2.9e-30 104.6 0.0 1.4 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain Aminotran_5 PF00266.19 KKK27015.1 - 3.8e-21 75.5 0.0 6.6e-21 74.7 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class-V ERAP1_C PF11838.8 KKK27016.1 - 7.9e-90 301.6 0.2 1.9e-88 297.1 0.2 2.4 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_M1 PF01433.20 KKK27016.1 - 2.5e-80 269.1 0.6 4.1e-80 268.4 0.6 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 KKK27016.1 - 4.1e-56 190.1 2.1 6.8e-56 189.4 2.1 1.4 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain DUF2808 PF10989.8 KKK27016.1 - 0.0024 17.9 0.1 0.0047 16.9 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2808) DUF3543 PF12063.8 KKK27017.1 - 1.1e-94 316.5 0.0 1.7e-94 315.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) Pkinase PF00069.25 KKK27017.1 - 1.7e-60 204.7 0.0 3.1e-60 203.8 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK27017.1 - 1.1e-41 142.8 0.0 1.9e-41 142.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase TAF8_C PF10406.9 KKK27017.1 - 0.015 15.9 0.2 0.056 14.0 0.2 2.1 1 0 0 1 1 1 0 Transcription factor TFIID complex subunit 8 C-term Cep57_MT_bd PF06657.13 KKK27020.1 - 2.9e-28 98.1 0.3 2.9e-28 98.1 0.3 4.0 3 0 0 3 3 3 1 Centrosome microtubule-binding domain of Cep57 MFS_1 PF07690.16 KKK27020.1 - 1.8e-26 92.9 19.1 2.9e-26 92.2 19.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Cep57_CLD_2 PF14197.6 KKK27020.1 - 6.8e-21 74.1 9.5 6.8e-21 74.1 9.5 4.3 4 0 0 4 4 4 1 Centrosome localisation domain of PPC89 Sugar_tr PF00083.24 KKK27020.1 - 5.7e-05 22.2 2.9 0.00014 20.8 2.9 1.6 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_3 PF05977.13 KKK27020.1 - 0.0051 15.3 0.9 0.01 14.3 0.9 1.4 1 0 0 1 1 1 1 Transmembrane secretion effector CHASE9 PF17153.4 KKK27020.1 - 0.38 10.9 2.5 2.5 8.3 0.5 2.4 2 0 0 2 2 2 0 Periplasmic sensor domain, extracellular CAF1A PF12253.8 KKK27020.1 - 1.2 9.4 9.5 0.95 9.7 1.9 3.2 2 0 0 2 2 2 0 Chromatin assembly factor 1 subunit A HALZ PF02183.18 KKK27020.1 - 7.8 6.8 9.3 2 8.7 1.3 2.9 2 0 0 2 2 2 0 Homeobox associated leucine zipper DAHP_synth_2 PF01474.16 KKK27022.1 - 3.3e-46 157.7 0.1 3.6e-46 157.6 0.1 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family DEAD PF00270.29 KKK27023.1 - 2.8e-47 160.7 0.0 1e-46 158.9 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KKK27023.1 - 1e-29 103.1 0.0 2.2e-28 98.8 0.1 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KKK27023.1 - 0.0012 18.9 0.0 0.0025 17.8 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2986 PF11661.8 KKK27023.1 - 0.0046 17.5 2.6 0.016 15.7 2.6 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2986) DUF3334 PF11813.8 KKK27023.1 - 0.13 12.0 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3334) DUF2244 PF10003.9 KKK27024.1 - 0.12 12.1 8.4 0.46 10.2 0.1 2.4 2 1 0 2 2 2 0 Integral membrane protein (DUF2244) DUF4282 PF14110.6 KKK27024.1 - 0.32 11.7 12.6 1.1 10.0 6.8 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4282) DUF2070 PF09843.9 KKK27024.1 - 0.46 8.7 9.3 0.3 9.3 7.4 1.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2070) PAP2 PF01569.21 KKK27025.1 - 1.9e-19 69.8 2.0 1.3e-18 67.0 2.0 2.2 1 1 0 1 1 1 1 PAP2 superfamily EI24 PF07264.11 KKK27025.1 - 0.00015 22.0 0.0 0.00036 20.8 0.0 1.5 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) But2 PF09792.9 KKK27026.1 - 4.7e-59 198.8 2.0 4.7e-59 198.8 2.0 3.8 3 2 1 4 4 4 1 Ubiquitin 3 binding protein But2 C-terminal domain Toxin_10 PF05431.11 KKK27026.1 - 0.037 13.5 0.3 0.037 13.5 0.3 2.0 2 1 0 2 2 2 0 Insecticidal Crystal Toxin, P42 Apt1 PF10351.9 KKK27026.1 - 1.6 7.5 14.0 2.6 6.8 14.0 1.5 1 0 0 1 1 1 0 Golgi-body localisation protein domain Anti-TRAP PF15777.5 KKK27026.1 - 2 8.4 5.2 4.4 7.4 0.0 3.9 5 0 0 5 5 5 0 Tryptophan RNA-binding attenuator protein inhibitory protein TFIIA PF03153.13 KKK27026.1 - 2.4 8.0 21.8 3.3 7.6 21.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Plasmodium_Vir PF05795.11 KKK27026.1 - 2.7 7.3 8.9 3.6 6.9 8.9 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Prefoldin_3 PF13758.6 KKK27027.1 - 6.2e-22 77.5 0.1 1.7e-21 76.1 0.1 1.7 1 0 0 1 1 1 1 Prefoldin subunit DUF3835 PF12927.7 KKK27027.1 - 0.035 15.0 3.6 0.21 12.5 0.1 3.6 3 1 0 3 3 3 0 Domain of unknown function (DUF3835) MAT1 PF06391.13 KKK27028.1 - 2.8e-41 141.6 12.4 3.6e-41 141.3 12.4 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4_5 PF17121.5 KKK27028.1 - 9.6e-33 111.8 9.0 1.5e-32 111.2 9.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KKK27028.1 - 0.00032 20.5 4.6 0.001 18.9 4.8 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KKK27028.1 - 0.00035 20.4 3.8 0.00072 19.4 3.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KKK27028.1 - 0.0052 17.1 6.9 0.0088 16.4 6.9 1.4 1 0 0 1 1 1 1 Ring finger domain Zn_ribbon_17 PF17120.5 KKK27028.1 - 0.0096 15.5 2.4 0.021 14.4 2.4 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_4 PF14570.6 KKK27028.1 - 0.011 15.5 4.9 0.21 11.4 1.9 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain DUF5338 PF17273.2 KKK27028.1 - 0.023 14.8 1.0 4.3 7.5 0.4 2.8 2 0 0 2 2 2 0 Family of unknown function (DUF5338) zf-RING_5 PF14634.6 KKK27028.1 - 0.036 14.0 8.4 0.46 10.5 9.2 2.2 1 1 1 2 2 2 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 KKK27028.1 - 0.21 11.6 6.0 0.43 10.6 6.0 1.5 1 0 0 1 1 1 0 RING-type zinc-finger Prok-RING_4 PF14447.6 KKK27028.1 - 1.5 8.8 9.2 30 4.6 9.9 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 DUF3797 PF12677.7 KKK27028.1 - 1.6 8.7 7.2 0.11 12.4 2.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3797) NGP1NT PF08153.12 KKK27030.1 - 2.1e-49 167.0 0.1 3.4e-49 166.3 0.1 1.3 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.23 KKK27030.1 - 2.3e-16 59.9 0.0 2.3e-13 50.2 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 KKK27030.1 - 0.00016 21.2 0.0 0.00049 19.6 0.0 1.8 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KKK27030.1 - 0.0015 18.5 0.0 0.0033 17.4 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase Dynamin_N PF00350.23 KKK27030.1 - 0.0015 18.6 0.1 0.27 11.3 0.0 3.2 2 1 1 3 3 3 1 Dynamin family Arf PF00025.21 KKK27030.1 - 0.0035 16.8 0.0 0.16 11.5 0.0 2.3 2 0 0 2 2 2 1 ADP-ribosylation factor family Mitoc_mL59 PF18126.1 KKK27031.1 - 4.8e-46 156.3 12.8 1.8e-45 154.4 12.8 1.8 1 1 0 1 1 1 1 Mitochondrial ribosomal protein mL59 Suf PF05843.14 KKK27032.1 - 3.7e-06 27.2 5.8 4.8e-05 23.5 0.2 3.3 3 1 1 4 4 4 1 Suppressor of forked protein (Suf) TPR_14 PF13428.6 KKK27032.1 - 0.0011 19.7 10.3 5.7 8.0 0.3 7.7 7 1 3 10 10 10 1 Tetratricopeptide repeat Aldose_epim PF01263.20 KKK27033.1 - 2.2e-40 138.8 0.0 2.6e-40 138.6 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase Glyco_hydro_65C PF03633.15 KKK27033.1 - 0.057 13.3 0.2 0.13 12.2 0.2 1.6 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, C-terminal domain Pkinase PF00069.25 KKK27034.1 - 2.8e-40 138.4 0.0 8.1e-40 136.8 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK27034.1 - 7.7e-28 97.5 0.0 1.1e-27 97.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KKK27034.1 - 0.002 17.5 0.0 0.0043 16.4 0.0 1.5 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KKK27034.1 - 0.0056 16.6 2.6 0.25 11.3 0.1 3.0 2 1 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KKK27034.1 - 0.0058 16.0 0.0 0.027 13.8 0.0 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Ric8 PF10165.9 KKK27035.1 - 7.2e-114 381.3 0.0 8.8e-114 381.1 0.0 1.1 1 0 0 1 1 1 1 Guanine nucleotide exchange factor synembryn Rif1_N PF12231.8 KKK27036.1 - 6.1e-141 469.8 0.0 9.6e-141 469.1 0.0 1.3 1 0 0 1 1 1 1 Rap1-interacting factor 1 N terminal DLH PF01738.18 KKK27037.1 - 1.3e-15 57.5 0.0 1e-13 51.3 0.0 2.1 2 0 0 2 2 2 2 Dienelactone hydrolase family ABC_membrane PF00664.23 KKK27038.1 - 2.6e-81 273.3 26.4 1.1e-45 156.4 7.8 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KKK27038.1 - 1.7e-56 190.5 0.0 1.4e-28 100.1 0.0 2.8 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KKK27038.1 - 2.1e-18 66.6 1.8 1.6e-07 31.0 0.0 4.3 3 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain Polysacc_synt_4 PF04669.13 KKK27038.1 - 1.1e-15 57.7 1.0 1.1e-14 54.5 1.0 2.5 1 1 0 1 1 1 1 Polysaccharide biosynthesis AAA_21 PF13304.6 KKK27038.1 - 3.8e-09 36.8 0.4 0.075 12.8 0.2 4.3 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KKK27038.1 - 1.3e-07 31.2 3.2 0.0093 15.7 0.5 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 KKK27038.1 - 5.3e-07 30.0 2.2 0.036 14.3 0.0 4.8 6 0 0 6 6 4 2 AAA domain AAA_16 PF13191.6 KKK27038.1 - 9e-06 26.2 0.2 0.03 14.7 0.1 3.1 2 1 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.6 KKK27038.1 - 2.9e-05 23.7 0.0 0.94 9.0 0.0 3.6 3 0 0 3 3 3 2 AAA domain RsgA_GTPase PF03193.16 KKK27038.1 - 8.8e-05 22.5 0.2 0.49 10.3 0.0 2.9 3 0 0 3 3 2 2 RsgA GTPase MMR_HSR1 PF01926.23 KKK27038.1 - 0.00012 22.2 0.1 0.76 9.9 0.0 2.8 2 1 0 2 2 2 2 50S ribosome-binding GTPase AAA_23 PF13476.6 KKK27038.1 - 0.00044 20.8 0.4 0.74 10.3 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.6 KKK27038.1 - 0.00049 19.9 2.2 1.3 8.7 0.0 3.2 3 0 0 3 3 3 2 AAA ATPase domain AAA_18 PF13238.6 KKK27038.1 - 0.00083 19.9 0.0 1.8 9.1 0.0 3.4 3 0 0 3 3 3 1 AAA domain ABC_ATPase PF09818.9 KKK27038.1 - 0.0012 17.8 2.2 0.74 8.5 0.0 3.7 4 0 0 4 4 4 1 Predicted ATPase of the ABC class AAA_33 PF13671.6 KKK27038.1 - 0.0042 17.3 0.0 3.3 7.9 0.0 3.0 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.17 KKK27038.1 - 0.0049 17.0 4.2 0.12 12.5 0.1 3.1 3 0 0 3 3 3 1 Helicase HerA, central domain AAA_5 PF07728.14 KKK27038.1 - 0.02 14.9 0.1 7.3 6.6 0.0 2.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) DUF3987 PF13148.6 KKK27038.1 - 0.022 13.8 0.1 2.3 7.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) SbcCD_C PF13558.6 KKK27038.1 - 0.04 14.1 0.0 8.4 6.7 0.0 3.0 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit APS_kinase PF01583.20 KKK27038.1 - 0.043 13.7 0.3 13 5.7 0.0 2.7 2 0 0 2 2 2 0 Adenylylsulphate kinase ATPase PF06745.13 KKK27038.1 - 0.056 12.8 9.1 5.2 6.3 0.5 3.8 4 0 0 4 4 4 0 KaiC NB-ARC PF00931.22 KKK27038.1 - 0.058 12.6 0.4 1.2 8.3 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain NACHT PF05729.12 KKK27038.1 - 0.061 13.2 0.4 15 5.4 0.6 2.8 2 0 0 2 2 2 0 NACHT domain AAA_24 PF13479.6 KKK27038.1 - 0.061 13.0 1.2 12 5.5 0.0 2.8 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 KKK27038.1 - 0.085 12.6 0.0 10 5.8 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_30 PF13604.6 KKK27038.1 - 0.086 12.5 0.1 8.8 6.0 0.0 3.0 3 0 0 3 3 3 0 AAA domain FtsK_SpoIIIE PF01580.18 KKK27038.1 - 0.093 12.1 0.2 5.6 6.2 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family RNA_helicase PF00910.22 KKK27038.1 - 0.16 12.4 0.0 32 5.0 0.0 2.6 2 0 0 2 2 2 0 RNA helicase zf-RING_2 PF13639.6 KKK27039.1 - 4.4e-14 52.5 4.3 7.6e-14 51.8 4.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KKK27039.1 - 1.6e-10 40.7 4.3 2.9e-10 39.8 4.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KKK27039.1 - 2.5e-10 39.9 2.0 5.7e-10 38.8 2.0 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 KKK27039.1 - 3.6e-09 36.4 2.8 6.4e-09 35.5 2.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KKK27039.1 - 1.7e-08 34.3 1.7 8.2e-08 32.2 1.4 2.3 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 KKK27039.1 - 2.8e-08 33.6 3.2 5.4e-08 32.7 3.2 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KKK27039.1 - 6.1e-06 26.0 1.9 1.1e-05 25.2 1.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KKK27039.1 - 6.6e-06 26.3 8.0 6.6e-06 26.3 8.0 2.5 2 1 0 2 2 1 1 RING-H2 zinc finger domain Zn_ribbon_17 PF17120.5 KKK27039.1 - 2.5e-05 23.8 2.8 4.3e-05 23.1 2.8 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 KKK27039.1 - 4.8e-05 23.1 4.1 0.0001 22.1 4.1 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KKK27039.1 - 6.1e-05 23.1 3.9 6.1e-05 23.1 3.9 1.9 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING ANAPC_CDC26 PF10471.9 KKK27039.1 - 0.00017 22.3 8.1 0.00039 21.2 8.1 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex APC subunit CDC26 Rtf2 PF04641.12 KKK27039.1 - 0.00062 19.2 0.6 0.091 12.1 0.0 2.1 2 0 0 2 2 2 1 Rtf2 RING-finger SARAF PF06682.12 KKK27039.1 - 0.00085 19.1 1.7 0.0011 18.7 1.7 1.1 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis TFIIA PF03153.13 KKK27039.1 - 0.0016 18.5 8.5 0.0018 18.3 8.5 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit FANCL_C PF11793.8 KKK27039.1 - 0.002 18.2 3.6 0.0078 16.4 3.6 2.0 1 1 0 1 1 1 1 FANCL C-terminal domain RINGv PF12906.7 KKK27039.1 - 0.0021 18.1 1.3 0.0058 16.7 1.3 1.8 1 1 0 1 1 1 1 RING-variant domain DUF2722 PF10846.8 KKK27039.1 - 0.0032 16.5 10.2 0.0042 16.1 10.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Zf_RING PF16744.5 KKK27039.1 - 0.0059 16.7 1.6 0.0059 16.7 1.6 2.0 2 1 0 2 2 1 1 KIAA1045 RING finger WASH-7_C PF14746.6 KKK27039.1 - 0.0059 16.3 0.3 0.0081 15.9 0.3 1.1 1 0 0 1 1 1 1 WASH complex subunit 7, C-terminal zf-RING_4 PF14570.6 KKK27039.1 - 0.006 16.3 4.0 0.011 15.5 4.0 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain PHD PF00628.29 KKK27039.1 - 0.0062 16.4 2.7 0.016 15.1 2.7 1.7 1 0 0 1 1 1 1 PHD-finger Chordopox_A13L PF05961.11 KKK27039.1 - 0.01 16.1 2.2 0.57 10.5 1.4 2.3 2 0 0 2 2 2 0 Chordopoxvirus A13L protein Spt20 PF12090.8 KKK27039.1 - 0.014 15.0 16.4 0.02 14.5 16.4 1.2 1 0 0 1 1 1 0 Spt20 family YfhO PF09586.10 KKK27039.1 - 0.014 13.6 0.1 0.018 13.3 0.1 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO RskA PF10099.9 KKK27039.1 - 0.019 15.3 0.1 0.028 14.7 0.1 1.3 1 0 0 1 1 1 0 Anti-sigma-K factor rskA zf-RING-like PF08746.11 KKK27039.1 - 0.023 15.0 2.2 0.065 13.6 2.2 1.8 1 1 0 1 1 1 0 RING-like domain zf-ANAPC11 PF12861.7 KKK27039.1 - 0.026 14.6 4.4 0.026 14.6 4.4 2.5 2 1 0 2 2 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Activator_LAG-3 PF11498.8 KKK27039.1 - 0.11 11.5 18.8 0.16 10.9 18.8 1.3 1 0 0 1 1 1 0 Transcriptional activator LAG-3 UPF0560 PF10577.9 KKK27039.1 - 0.12 10.9 5.0 0.13 10.7 5.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 FAM176 PF14851.6 KKK27039.1 - 0.14 11.8 0.0 3.3 7.4 0.1 2.1 2 0 0 2 2 2 0 FAM176 family OATP PF03137.20 KKK27039.1 - 0.19 10.0 0.0 0.21 9.8 0.0 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Prok-RING_1 PF14446.6 KKK27039.1 - 0.22 11.5 3.4 0.46 10.4 0.6 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 MFS_Mycoplasma PF07672.13 KKK27039.1 - 0.28 10.4 2.9 0.16 11.3 0.6 1.6 1 1 1 2 2 2 0 Mycoplasma MFS transporter Thioredoxin_4 PF13462.6 KKK27039.1 - 0.29 11.3 8.2 0.062 13.5 2.9 2.0 2 0 0 2 2 2 0 Thioredoxin Neur_chan_memb PF02932.16 KKK27039.1 - 0.35 10.9 2.3 0.72 9.9 2.3 1.4 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region zf-C3H2C3 PF17122.5 KKK27039.1 - 0.61 10.2 4.4 1.8 8.6 4.4 1.9 1 1 0 1 1 1 0 Zinc-finger Headcase PF16002.5 KKK27039.1 - 0.65 9.4 3.6 4.2 6.8 0.1 2.5 2 1 0 2 2 2 0 Headcase protein DUF5421 PF17458.2 KKK27039.1 - 1.7 7.9 8.8 2.4 7.5 8.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5421) DUF4834 PF16118.5 KKK27039.1 - 5.6 8.0 11.1 14 6.7 11.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) Roughex PF06020.11 KKK27039.1 - 5.7 5.9 7.5 7.1 5.6 7.5 1.1 1 0 0 1 1 1 0 Drosophila roughex protein AA_permease PF00324.21 KKK27040.1 - 8.8e-139 463.2 36.1 1e-138 463.0 36.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KKK27040.1 - 1.9e-36 125.8 39.8 2.4e-36 125.5 39.8 1.1 1 0 0 1 1 1 1 Amino acid permease Pkinase PF00069.25 KKK27041.1 - 1.3e-25 90.3 0.0 8.3e-25 87.6 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK27041.1 - 3.8e-09 36.2 0.0 5.9e-08 32.3 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase DUF3435 PF11917.8 KKK27041.1 - 0.00065 18.8 0.0 0.00085 18.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) Pkinase_fungal PF17667.1 KKK27041.1 - 0.11 11.3 0.0 2.2 7.0 0.0 2.2 2 0 0 2 2 2 0 Fungal protein kinase Sulfotransfer_4 PF17784.1 KKK27042.1 - 7.3e-40 137.1 0.0 7.1e-22 78.3 0.0 2.0 1 1 1 2 2 2 2 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KKK27042.1 - 0.094 13.1 0.4 6.2 7.1 0.0 2.2 1 1 1 2 2 2 0 Sulfotransferase family Rrf2 PF02082.20 KKK27043.1 - 0.019 15.3 0.0 0.058 13.7 0.0 1.8 1 0 0 1 1 1 0 Transcriptional regulator MarR PF01047.22 KKK27043.1 - 0.15 12.0 0.0 1.2 9.1 0.0 2.5 3 0 0 3 3 3 0 MarR family LacI PF00356.21 KKK27043.1 - 0.16 11.8 0.5 0.5 10.2 0.0 2.1 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family FAD_binding_3 PF01494.19 KKK27044.1 - 2.8e-09 36.7 0.0 1.7e-08 34.2 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KKK27044.1 - 1.6e-06 28.0 0.0 0.039 13.5 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KKK27044.1 - 0.0076 15.5 0.0 0.31 10.2 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KKK27044.1 - 0.015 14.4 0.0 0.022 13.8 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 KKK27044.1 - 0.2 10.3 0.0 1.2 7.8 0.1 1.9 2 0 0 2 2 2 0 HI0933-like protein Scytalone_dh PF02982.14 KKK27045.1 - 3.3e-62 209.0 0.6 1.7e-48 164.5 0.2 2.0 2 0 0 2 2 2 2 Scytalone dehydratase SnoaL_4 PF13577.6 KKK27045.1 - 5.4e-05 23.3 0.0 7.8e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain adh_short_C2 PF13561.6 KKK27046.1 - 5.2e-56 189.8 1.6 7e-56 189.4 1.6 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KKK27046.1 - 5.1e-48 163.1 1.7 6.3e-48 162.8 1.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KKK27046.1 - 1.9e-10 41.0 0.6 2.6e-10 40.5 0.6 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 KKK27046.1 - 0.0087 15.5 0.0 0.011 15.1 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) 2-Hacid_dh_C PF02826.19 KKK27046.1 - 0.03 13.7 0.2 0.22 10.9 0.1 2.0 1 1 1 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ORC2 PF04084.14 KKK27046.1 - 0.11 11.4 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 2 ketoacyl-synt PF00109.26 KKK27047.1 - 1.3e-68 231.3 0.0 2.2e-68 230.6 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain SAT PF16073.5 KKK27047.1 - 1.9e-46 158.8 0.0 9.1e-46 156.5 0.0 2.1 2 0 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Acyl_transf_1 PF00698.21 KKK27047.1 - 1.5e-43 149.5 0.0 1e-42 146.8 0.0 2.1 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KKK27047.1 - 7.1e-34 116.4 0.8 2.3e-33 114.7 0.8 2.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain EthD PF07110.11 KKK27047.1 - 8.2e-21 75.0 0.2 3.5e-20 72.9 0.2 2.2 1 0 0 1 1 1 1 EthD domain PP-binding PF00550.25 KKK27047.1 - 2.4e-10 40.6 0.7 7.1e-10 39.1 0.7 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site KAsynt_C_assoc PF16197.5 KKK27047.1 - 1.9e-07 31.5 0.1 7.9e-07 29.5 0.0 2.0 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension MmlI PF09448.10 KKK27047.1 - 0.16 12.4 0.1 0.82 10.1 0.1 2.2 2 0 0 2 2 2 0 Methylmuconolactone methyl-isomerase Thiolase_N PF00108.23 KKK27047.1 - 0.23 10.8 0.8 0.49 9.7 0.8 1.5 1 0 0 1 1 1 0 Thiolase, N-terminal domain DUF1772 PF08592.11 KKK27048.1 - 2.5e-31 108.8 9.5 2.9e-31 108.6 9.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) ApoO PF09769.9 KKK27048.1 - 0.054 13.4 0.3 0.054 13.4 0.3 1.9 3 0 0 3 3 3 0 Apolipoprotein O AflR PF08493.10 KKK27049.1 - 1.1e-35 123.6 0.8 2.2e-35 122.5 0.8 1.4 1 0 0 1 1 1 1 Aflatoxin regulatory protein Zn_clus PF00172.18 KKK27049.1 - 4.2e-07 30.0 8.9 7.3e-07 29.2 8.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Lactamase_B PF00753.27 KKK27050.1 - 2e-16 60.6 7.7 1.2e-14 54.8 7.7 2.2 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KKK27050.1 - 7.2e-05 22.4 1.3 0.00018 21.1 1.3 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain BLACT_WH PF17778.1 KKK27050.1 - 0.00015 21.7 0.4 0.0025 17.8 0.0 2.9 3 0 0 3 3 3 1 Beta-lactamase associated winged helix domain His_Phos_2 PF00328.22 KKK27051.1 - 7.5e-12 45.3 0.0 3.1e-10 40.0 0.0 2.1 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Amnionless PF14828.6 KKK27051.1 - 0.13 11.1 0.0 0.18 10.6 0.0 1.1 1 0 0 1 1 1 0 Amnionless AMP-binding PF00501.28 KKK27054.1 - 7.1e-88 295.0 0.0 1.1e-87 294.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KKK27054.1 - 5.9e-06 27.2 0.2 2.3e-05 25.3 0.1 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain PBP_like PF12727.7 KKK27054.1 - 0.18 10.9 0.0 0.36 9.9 0.0 1.4 1 0 0 1 1 1 0 PBP superfamily domain PQ-loop PF04193.14 KKK27056.1 - 5.2e-40 135.0 6.6 3.7e-21 74.6 0.2 2.5 2 0 0 2 2 2 2 PQ loop repeat ER_lumen_recept PF00810.18 KKK27056.1 - 0.044 14.6 0.0 0.8 10.5 0.0 2.3 2 0 0 2 2 2 0 ER lumen protein retaining receptor FTR1 PF03239.14 KKK27056.1 - 1.7 7.7 5.5 2.2 7.4 2.8 2.1 2 0 0 2 2 2 0 Iron permease FTR1 family Tcf25 PF04910.14 KKK27057.1 - 8.4e-76 255.3 0.0 1.1e-75 254.9 0.0 1.1 1 0 0 1 1 1 1 Transcriptional repressor TCF25 TPR_12 PF13424.6 KKK27057.1 - 0.0032 17.7 1.0 0.15 12.4 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 KKK27057.1 - 0.023 14.8 1.1 0.065 13.4 0.2 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 KKK27057.1 - 0.034 14.9 0.4 0.71 10.9 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF3246 PF11596.8 KKK27057.1 - 0.41 10.1 4.0 0.58 9.6 4.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) Glyco_hydro_53 PF07745.13 KKK27058.1 - 4.8e-98 328.3 0.0 5.4e-98 328.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 53 Carb_kinase PF01256.17 KKK27059.1 - 3.9e-54 183.7 0.4 4.3e-53 180.3 0.4 2.0 1 1 0 1 1 1 1 Carbohydrate kinase DUF4148 PF13663.6 KKK27059.1 - 0.19 11.9 0.7 0.82 9.9 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4148) SPT2 PF08243.11 KKK27060.1 - 2.7e-06 27.9 21.2 7.9e-06 26.4 21.2 1.8 1 1 0 1 1 1 1 SPT2 chromatin protein Kelch_4 PF13418.6 KKK27061.1 - 1.7e-05 24.8 1.1 0.16 12.0 0.1 4.1 3 1 0 3 3 3 3 Galactose oxidase, central domain Kelch_5 PF13854.6 KKK27061.1 - 0.018 15.0 0.1 0.13 12.3 0.0 2.4 2 0 0 2 2 2 0 Kelch motif MIOX PF05153.15 KKK27062.1 - 1.9e-114 381.4 0.9 3e-114 380.8 0.9 1.3 1 1 0 1 1 1 1 Myo-inositol oxygenase HD PF01966.22 KKK27062.1 - 0.027 14.7 0.0 1.7 8.9 0.0 2.5 2 0 0 2 2 2 0 HD domain Speriolin_C PF15059.6 KKK27062.1 - 0.12 12.5 0.4 0.2 11.8 0.4 1.3 1 0 0 1 1 1 0 Speriolin C-terminus CP12 PF02672.15 KKK27062.1 - 0.15 12.8 1.6 0.21 12.4 0.3 1.9 2 0 0 2 2 2 0 CP12 domain Fungal_trans PF04082.18 KKK27063.1 - 1.2e-28 99.9 0.5 2e-28 99.1 0.3 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK27063.1 - 6e-09 35.9 11.4 1.4e-08 34.7 11.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CLZ PF16526.5 KKK27063.1 - 0.021 15.2 1.5 0.037 14.4 1.5 1.3 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels HALZ PF02183.18 KKK27063.1 - 0.043 14.0 4.4 0.08 13.2 4.4 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper TolA_bind_tri PF16331.5 KKK27063.1 - 0.12 12.4 8.7 0.22 11.6 8.7 1.3 1 0 0 1 1 1 0 TolA binding protein trimerisation DHR10 PF18595.1 KKK27063.1 - 0.43 10.7 3.4 0.71 9.9 3.4 1.3 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain EGF_CA PF07645.15 KKK27064.1 - 0.0004 20.5 7.6 0.0004 20.5 7.6 2.0 2 0 0 2 2 2 1 Calcium-binding EGF domain EGF_3 PF12947.7 KKK27064.1 - 0.0034 17.5 5.4 0.0034 17.5 5.4 2.3 2 1 0 2 2 2 1 EGF domain FXa_inhibition PF14670.6 KKK27064.1 - 0.49 10.7 13.9 0.27 11.6 9.2 2.8 2 1 1 3 3 3 0 Coagulation Factor Xa inhibitory site cEGF PF12662.7 KKK27064.1 - 5.4 7.0 12.1 0.17 11.8 4.7 2.4 2 1 0 2 2 2 0 Complement Clr-like EGF-like AAA PF00004.29 KKK27065.1 - 6.8e-54 181.9 0.0 4e-43 147.0 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.11 KKK27065.1 - 1.8e-29 101.9 0.8 3.9e-29 100.9 0.8 1.6 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_lid_3 PF17862.1 KKK27065.1 - 4.2e-15 55.3 0.4 6e-09 35.6 0.1 2.6 2 0 0 2 2 2 2 AAA+ lid domain AAA_2 PF07724.14 KKK27065.1 - 2.6e-06 27.7 0.0 0.076 13.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) NACHT PF05729.12 KKK27065.1 - 3.2e-06 27.1 4.7 0.0012 18.8 0.0 3.9 4 0 0 4 4 4 2 NACHT domain RuvB_N PF05496.12 KKK27065.1 - 6.2e-05 22.8 0.0 0.0094 15.7 0.0 2.8 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KKK27065.1 - 7.4e-05 23.2 14.9 0.026 14.9 0.2 5.1 4 2 2 6 6 5 2 AAA ATPase domain TsaE PF02367.17 KKK27065.1 - 0.00013 21.9 0.9 0.65 10.0 0.1 3.1 3 0 0 3 3 3 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE IstB_IS21 PF01695.17 KKK27065.1 - 0.00014 21.6 0.6 0.14 11.9 0.0 2.7 3 0 0 3 3 3 2 IstB-like ATP binding protein RNA_helicase PF00910.22 KKK27065.1 - 0.00022 21.6 0.3 9.2 6.7 0.0 4.1 4 0 0 4 4 4 0 RNA helicase AAA_18 PF13238.6 KKK27065.1 - 0.00025 21.6 0.1 0.82 10.2 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_14 PF13173.6 KKK27065.1 - 0.00042 20.4 0.0 2.1 8.4 0.0 3.1 2 1 0 2 2 2 2 AAA domain AAA_22 PF13401.6 KKK27065.1 - 0.00051 20.3 5.7 0.59 10.4 0.1 4.4 3 2 0 3 3 3 2 AAA domain AAA_5 PF07728.14 KKK27065.1 - 0.00056 19.9 0.1 0.97 9.4 0.0 3.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 KKK27065.1 - 0.00073 19.7 0.0 0.13 12.4 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 KKK27065.1 - 0.0038 16.8 0.0 0.23 10.9 0.0 2.6 2 0 0 2 2 2 1 P-loop containing dynein motor region TIP49 PF06068.13 KKK27065.1 - 0.0039 16.5 0.0 1.2 8.2 0.0 2.3 2 0 0 2 2 2 1 TIP49 P-loop domain PEX-2N PF09263.10 KKK27065.1 - 0.0041 17.4 0.0 3.1 8.2 0.0 2.6 2 0 0 2 2 2 1 Peroxisome biogenesis factor 1, N-terminal ATPase_2 PF01637.18 KKK27065.1 - 0.0069 16.3 1.6 5.5 6.8 0.0 4.0 4 1 0 4 4 3 0 ATPase domain predominantly from Archaea Zeta_toxin PF06414.12 KKK27065.1 - 0.012 14.9 1.7 2.2 7.5 0.0 2.7 3 0 0 3 3 3 0 Zeta toxin Mg_chelatase PF01078.21 KKK27065.1 - 0.016 14.6 1.8 0.19 11.1 0.1 3.1 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI DUF2075 PF09848.9 KKK27065.1 - 0.02 14.2 0.5 1.8 7.7 0.0 2.7 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) Cytidylate_kin2 PF13189.6 KKK27065.1 - 0.023 14.9 0.0 4.9 7.2 0.0 3.2 3 0 0 3 3 3 0 Cytidylate kinase-like family AAA_19 PF13245.6 KKK27065.1 - 0.023 15.0 0.9 0.72 10.2 0.0 3.1 3 0 0 3 3 3 0 AAA domain Sigma54_activat PF00158.26 KKK27065.1 - 0.031 14.0 0.1 4.3 7.0 0.0 3.2 4 0 0 4 4 3 0 Sigma-54 interaction domain AAA_28 PF13521.6 KKK27065.1 - 0.033 14.4 0.0 13 6.0 0.0 2.8 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 KKK27065.1 - 0.034 13.5 2.5 1.4 8.3 0.1 3.0 3 0 0 3 3 3 0 KaiC Viral_helicase1 PF01443.18 KKK27065.1 - 0.038 13.7 0.0 0.41 10.4 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase SKI PF01202.22 KKK27065.1 - 0.085 13.0 0.0 21 5.2 0.0 2.6 2 0 0 2 2 2 0 Shikimate kinase NTPase_1 PF03266.15 KKK27065.1 - 0.13 12.1 0.1 2.1 8.3 0.0 2.3 2 0 0 2 2 2 0 NTPase Sigma54_activ_2 PF14532.6 KKK27065.1 - 0.14 12.3 0.0 5 7.3 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain T2SSE PF00437.20 KKK27065.1 - 0.21 10.6 2.5 0.66 9.0 0.1 2.7 3 0 0 3 3 3 0 Type II/IV secretion system protein ABC_tran PF00005.27 KKK27065.1 - 0.25 11.9 3.7 24 5.4 0.0 3.9 4 0 0 4 4 4 0 ABC transporter AAA_25 PF13481.6 KKK27065.1 - 0.57 9.7 4.2 2.8 7.5 0.1 3.6 2 2 1 4 4 4 0 AAA domain AAA_29 PF13555.6 KKK27065.1 - 0.67 9.7 3.1 13 5.6 1.0 3.2 3 0 0 3 3 3 0 P-loop containing region of AAA domain MCM PF00493.23 KKK27066.1 - 5.1e-104 346.3 0.0 8.9e-104 345.5 0.0 1.4 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KKK27066.1 - 2.8e-33 114.4 0.5 5e-33 113.6 0.5 1.3 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KKK27066.1 - 1.9e-21 76.3 0.4 5.2e-21 74.9 0.4 1.8 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KKK27066.1 - 8.3e-20 71.3 1.6 2.1e-19 70.0 1.6 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 KKK27066.1 - 5.7e-07 29.1 0.0 5.4e-05 22.7 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KKK27066.1 - 3.2e-06 27.2 0.0 9e-06 25.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 KKK27066.1 - 0.01 15.7 0.0 0.053 13.4 0.0 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_lid_2 PF17863.1 KKK27066.1 - 0.035 13.9 0.0 0.1 12.5 0.0 1.7 1 0 0 1 1 1 0 AAA lid domain PGI PF00342.19 KKK27067.1 - 3.2e-240 797.8 0.7 3.7e-240 797.6 0.7 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase DSHCT PF08148.12 KKK27068.1 - 8.5e-52 175.1 0.5 2.5e-51 173.6 0.5 1.9 1 0 0 1 1 1 1 DSHCT (NUC185) domain Ski2_N PF17911.1 KKK27068.1 - 2.6e-40 137.4 0.0 5.9e-40 136.2 0.0 1.6 1 0 0 1 1 1 1 Ski2 N-terminal region rRNA_proc-arch PF13234.6 KKK27068.1 - 1.9e-25 90.3 0.2 5e-25 89.0 0.0 1.8 2 0 0 2 2 2 1 rRNA-processing arch domain DEAD PF00270.29 KKK27068.1 - 3.5e-18 66.0 0.0 7.5e-18 64.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KKK27068.1 - 1.1e-06 28.9 0.0 3.6e-06 27.3 0.0 1.9 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KKK27068.1 - 9.4e-06 25.7 0.0 2.3e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Pkinase PF00069.25 KKK27069.1 - 1.5e-60 204.8 0.0 2e-60 204.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK27069.1 - 5.1e-27 94.8 0.0 7.6e-27 94.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KKK27069.1 - 0.0073 15.7 0.1 0.013 14.9 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KKK27069.1 - 0.023 13.6 0.0 0.034 13.1 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Kinase-like PF14531.6 KKK27069.1 - 0.12 11.6 0.0 1.2 8.4 0.0 2.0 1 1 0 2 2 2 0 Kinase-like APH PF01636.23 KKK27069.1 - 0.15 11.9 0.0 0.15 11.9 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family Radial_spoke_3 PF06098.11 KKK27069.1 - 1.8 7.8 7.5 3.5 6.8 7.5 1.4 1 0 0 1 1 1 0 Radial spoke protein 3 Ribosomal_S21 PF01165.20 KKK27070.1 - 1.8e-10 40.3 1.3 2.8e-10 39.7 1.3 1.3 1 0 0 1 1 1 1 Ribosomal protein S21 TPR_1 PF00515.28 KKK27071.1 - 7.9e-13 47.6 3.8 8.7e-06 25.3 0.0 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 KKK27071.1 - 5.2e-11 41.8 4.7 0.00066 19.6 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 KKK27071.1 - 7.3e-08 32.6 0.0 6.3e-05 23.2 0.0 3.4 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 KKK27071.1 - 4.5e-07 29.6 0.5 0.0006 19.8 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 KKK27071.1 - 6.4e-05 22.6 0.6 0.0011 18.6 0.1 3.0 2 1 1 3 3 3 1 TPR repeat TPR_9 PF13371.6 KKK27071.1 - 0.00047 20.3 0.0 0.84 9.8 0.0 2.9 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 KKK27071.1 - 0.00079 19.3 0.0 0.015 15.3 0.0 2.8 1 1 1 2 2 2 1 Tetratricopeptide repeat Serglycin PF04360.12 KKK27071.1 - 0.0028 17.6 2.5 0.0059 16.6 2.5 1.5 1 0 0 1 1 1 1 Serglycin TPR_6 PF13174.6 KKK27071.1 - 0.004 17.7 0.8 38 5.2 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 KKK27071.1 - 0.0045 17.6 1.2 0.07 13.8 0.2 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat PB1 PF00564.24 KKK27071.1 - 0.013 15.4 0.0 0.027 14.4 0.0 1.5 1 0 0 1 1 1 0 PB1 domain Aminotran_1_2 PF00155.21 KKK27072.1 - 9e-73 245.5 0.0 1.1e-72 245.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II HMA PF00403.26 KKK27073.1 - 1.6e-13 50.9 0.0 3.2e-13 49.9 0.0 1.5 1 0 0 1 1 1 1 Heavy-metal-associated domain Sod_Cu PF00080.20 KKK27073.1 - 1.9e-08 34.6 0.0 3.2e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) RRM_1 PF00076.22 KKK27074.1 - 1.1e-05 25.1 0.0 1.9e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Rhodanese PF00581.20 KKK27076.1 - 2.3e-10 41.0 0.0 2.9e-10 40.6 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain Cpn60_TCP1 PF00118.24 KKK27076.1 - 0.046 12.3 0.0 0.052 12.2 0.0 1.0 1 0 0 1 1 1 0 TCP-1/cpn60 chaperonin family Peptidase_C50 PF03568.17 KKK27076.1 - 0.11 11.6 0.0 0.12 11.5 0.0 1.1 1 0 0 1 1 1 0 Peptidase family C50 Methyltransf_28 PF02636.17 KKK27077.1 - 3.3e-84 282.6 0.0 4.7e-84 282.1 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase IBN_N PF03810.19 KKK27079.1 - 4.6e-18 64.9 2.1 1.1e-14 54.1 0.0 4.3 4 0 0 4 4 4 1 Importin-beta N-terminal domain Cse1 PF08506.10 KKK27079.1 - 2.3e-07 30.0 0.0 5.7e-07 28.7 0.0 1.7 1 0 0 1 1 1 1 Cse1 RTP1_C1 PF10363.9 KKK27079.1 - 0.00089 19.4 0.3 0.23 11.6 0.1 3.0 2 0 0 2 2 2 1 Required for nuclear transport of RNA pol II C-terminus 1 Xpo1 PF08389.12 KKK27079.1 - 0.0074 16.4 1.8 0.15 12.1 0.0 3.5 3 1 0 3 3 3 1 Exportin 1-like protein DCB PF16213.5 KKK27079.1 - 0.16 11.6 0.2 0.46 10.1 0.2 1.8 1 0 0 1 1 1 0 Dimerisation and cyclophilin-binding domain of Mon2 HEAT_EZ PF13513.6 KKK27079.1 - 1.3 9.6 7.8 24 5.6 0.6 5.4 6 2 1 7 7 7 0 HEAT-like repeat RRM_1 PF00076.22 KKK27080.1 - 9e-07 28.6 0.0 2.4e-06 27.3 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KKK27080.1 - 2.2e-06 27.6 0.0 4e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif FAM153 PF15722.5 KKK27080.1 - 0.04 14.3 0.5 0.093 13.1 0.5 1.6 1 0 0 1 1 1 0 FAM153 family YhdX PF17444.2 KKK27080.1 - 0.44 10.4 2.9 4.7 7.1 1.7 2.4 2 0 0 2 2 2 0 Uncharacterized YhdX-like SlyX PF04102.12 KKK27081.1 - 0.0031 18.1 1.8 0.83 10.3 0.3 2.6 2 0 0 2 2 2 2 SlyX NEMO PF11577.8 KKK27081.1 - 0.15 12.1 0.3 0.4 10.7 0.1 1.8 2 0 0 2 2 2 0 NF-kappa-B essential modulator NEMO DivIC PF04977.15 KKK27081.1 - 0.78 9.6 2.5 0.58 10.0 0.4 1.8 2 0 0 2 2 2 0 Septum formation initiator DUF2415 PF10313.9 KKK27082.1 - 2.5e-15 56.1 0.1 7.9e-15 54.5 0.0 2.0 2 0 0 2 2 2 1 Uncharacterised protein domain (DUF2415) NAM-associated PF14303.6 KKK27082.1 - 5.2 7.8 5.4 4.5 8.0 3.8 1.7 1 1 0 1 1 1 0 No apical meristem-associated C-terminal domain CPSase_L_D2 PF02786.17 KKK27083.1 - 3.2e-107 356.8 0.0 1.7e-83 279.3 0.0 2.2 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.19 KKK27083.1 - 8.6e-41 139.1 0.1 2.4e-40 137.7 0.0 1.8 2 0 0 2 2 2 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain Dala_Dala_lig_C PF07478.13 KKK27083.1 - 9e-18 64.5 0.1 5.3e-08 32.7 0.0 2.4 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 KKK27083.1 - 4.5e-17 62.2 0.0 4.3e-07 29.7 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.6 KKK27083.1 - 8.9e-12 44.9 0.0 8.8e-05 22.3 0.0 3.1 2 1 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_5 PF13549.6 KKK27083.1 - 1.3e-05 24.8 0.1 0.029 13.8 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain GARS_A PF01071.19 KKK27083.1 - 0.0012 18.7 0.0 0.21 11.3 0.0 2.6 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain SET PF00856.28 KKK27084.1 - 1.9e-13 51.2 0.0 2.6e-12 47.5 0.0 2.4 2 1 0 2 2 2 1 SET domain zf-MYND PF01753.18 KKK27084.1 - 2.9e-08 33.7 8.6 7.8e-08 32.3 8.7 1.7 1 1 0 1 1 1 1 MYND finger Ribosomal_S19 PF00203.21 KKK27085.1 - 3.6e-35 119.7 0.3 5e-35 119.2 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 Ribosomal_60s PF00428.19 KKK27086.1 - 3.2e-27 95.0 14.2 3.6e-27 94.8 14.2 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein HSP70 PF00012.20 KKK27088.1 - 2.5e-267 887.9 18.5 2.9e-267 887.8 18.5 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KKK27088.1 - 6.8e-16 58.0 8.2 2.2e-14 53.0 2.0 3.0 3 0 0 3 3 3 2 MreB/Mbl protein FGGY_C PF02782.16 KKK27088.1 - 0.0005 19.8 0.0 0.0012 18.6 0.0 1.8 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain MukF_M PF17192.4 KKK27088.1 - 0.073 12.8 1.3 0.17 11.6 1.3 1.6 1 0 0 1 1 1 0 MukF middle domain Big_3_4 PF13754.6 KKK27088.1 - 0.079 12.7 0.0 2.6 7.8 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function Tom22 PF04281.13 KKK27088.1 - 0.14 12.0 6.3 0.36 10.6 6.3 1.7 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 SMBP PF16785.5 KKK27088.1 - 1.1 9.6 5.0 0.88 9.8 2.6 2.2 2 0 0 2 2 2 0 Small metal-binding protein YpzG PF14139.6 KKK27090.1 - 0.066 13.4 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 YpzG-like protein PP2C PF00481.21 KKK27091.1 - 7.8e-46 156.8 0.0 1.4e-45 155.9 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 KKK27091.1 - 5.7e-06 26.1 0.1 1.2e-05 25.0 0.1 1.5 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 KKK27091.1 - 9e-05 22.5 0.1 0.31 10.9 0.0 2.8 3 0 0 3 3 3 2 Stage II sporulation protein E (SpoIIE) Methyltransf_16 PF10294.9 KKK27092.1 - 8.2e-07 28.9 0.0 0.017 14.9 0.0 3.0 3 0 0 3 3 3 2 Lysine methyltransferase Macoilin PF09726.9 KKK27092.1 - 0.16 10.5 0.0 0.21 10.1 0.0 1.1 1 0 0 1 1 1 0 Macoilin family NDT80_PhoG PF05224.12 KKK27093.1 - 9.3e-26 91.2 0.1 1.3e-25 90.7 0.1 1.2 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family eIF3g PF12353.8 KKK27094.1 - 9.2e-45 152.1 2.8 1.4e-44 151.5 2.8 1.3 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.22 KKK27094.1 - 4e-17 61.8 0.0 6.8e-17 61.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH_7 PF18586.1 KKK27094.1 - 0.021 15.1 0.2 0.058 13.7 0.2 1.7 1 0 0 1 1 1 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 1 ribosomal_L24 PF17136.4 KKK27094.1 - 0.088 13.2 0.9 0.088 13.2 0.9 2.1 2 0 0 2 2 2 0 Ribosomal proteins 50S L24/mitochondrial 39S L24 Transp_cyt_pur PF02133.15 KKK27095.1 - 3e-49 168.0 39.9 3.4e-49 167.8 39.9 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Beta-lactamase PF00144.24 KKK27097.1 - 2.3e-44 152.0 0.0 5.1e-44 150.9 0.0 1.4 1 1 0 1 1 1 1 Beta-lactamase Beta-lactamase2 PF13354.6 KKK27097.1 - 0.1 12.2 0.2 0.29 10.7 0.0 1.8 2 1 0 2 2 2 0 Beta-lactamase enzyme family NMO PF03060.15 KKK27098.1 - 4.2e-47 161.1 4.8 6.7e-47 160.5 3.4 1.9 1 1 1 2 2 2 1 Nitronate monooxygenase IMPDH PF00478.25 KKK27098.1 - 1.8e-10 40.3 1.1 7.8e-10 38.3 1.1 1.9 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 KKK27098.1 - 1.1e-05 24.6 1.7 1.7e-05 24.0 1.7 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 KKK27098.1 - 0.01 15.0 1.1 0.022 13.9 1.1 1.5 1 0 0 1 1 1 0 Conserved region in glutamate synthase DHO_dh PF01180.21 KKK27098.1 - 0.071 12.3 0.2 0.13 11.5 0.2 1.3 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase Methyltransf_23 PF13489.6 KKK27099.1 - 6.8e-13 48.8 0.0 9e-13 48.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKK27099.1 - 3.2e-09 37.4 0.0 5.4e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KKK27099.1 - 1.3e-08 35.4 0.0 2e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KKK27099.1 - 5.7e-08 32.7 0.0 6.9e-08 32.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KKK27099.1 - 2.9e-06 26.8 0.0 3.7e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 KKK27099.1 - 7.8e-06 26.6 0.0 1.2e-05 25.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 KKK27099.1 - 8.5e-06 24.9 0.0 1.2e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) DUF938 PF06080.12 KKK27099.1 - 0.0041 16.9 0.0 0.052 13.3 0.0 2.6 1 1 0 1 1 1 1 Protein of unknown function (DUF938) Methyltransf_24 PF13578.6 KKK27099.1 - 0.011 16.7 0.0 0.024 15.7 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain ArfGap PF01412.18 KKK27100.1 - 5.1e-33 113.6 0.7 8.3e-33 112.9 0.7 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Pterin_bind PF00809.22 KKK27101.1 - 1.4e-77 260.7 0.0 1.8e-77 260.3 0.0 1.1 1 0 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.20 KKK27101.1 - 8.6e-36 122.9 0.0 2.1e-35 121.6 0.0 1.6 2 0 0 2 2 2 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) ThiP_synth PF10120.9 KKK27101.1 - 0.077 12.6 0.1 0.15 11.7 0.1 1.4 1 0 0 1 1 1 0 Thiamine-phosphate synthase MR_MLE_C PF13378.6 KKK27102.1 - 9.6e-58 195.3 0.0 1.3e-57 194.9 0.0 1.2 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 KKK27102.1 - 4.4e-07 30.1 0.0 9e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain TIM21 PF08294.11 KKK27103.1 - 5.7e-42 143.0 0.0 7.2e-42 142.7 0.0 1.1 1 0 0 1 1 1 1 TIM21 Coa1 PF08695.10 KKK27103.1 - 8.8e-05 22.2 0.0 0.00018 21.2 0.0 1.5 1 1 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 Asp4 PF16996.5 KKK27103.1 - 0.14 11.9 0.1 0.27 11.1 0.1 1.4 1 0 0 1 1 1 0 Accessory secretory protein Sec Asp4 PWI PF01480.17 KKK27104.1 - 1.6e-16 60.4 1.0 3.6e-16 59.2 1.0 1.6 1 0 0 1 1 1 1 PWI domain DinB_2 PF12867.7 KKK27104.1 - 6.8 7.2 13.5 1.7e+03 -0.5 12.6 3.6 2 1 0 2 2 2 0 DinB superfamily 60KD_IMP PF02096.20 KKK27105.1 - 4e-08 33.3 1.3 5.4e-06 26.4 0.1 2.1 2 0 0 2 2 2 2 60Kd inner membrane protein DUF1187 PF06688.11 KKK27106.1 - 0.12 12.7 0.1 0.25 11.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1187) zf-C2H2 PF00096.26 KKK27107.1 - 9.6e-13 47.8 13.7 4e-06 27.0 4.4 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KKK27107.1 - 4.2e-12 45.9 9.0 2e-07 31.2 0.2 3.6 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 KKK27107.1 - 5.6e-08 33.0 12.4 0.0018 19.0 3.1 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KKK27107.1 - 2.5e-07 30.5 7.5 0.00077 19.4 1.0 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.7 KKK27107.1 - 0.00014 22.1 1.6 0.036 14.4 0.5 3.2 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KKK27107.1 - 0.0018 18.5 8.6 0.17 12.2 0.3 3.6 4 0 0 4 4 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 KKK27107.1 - 0.037 13.8 5.9 1.7 8.5 1.3 3.3 3 0 0 3 3 3 0 zinc-finger C2H2-type Zn_ribbon_recom PF13408.6 KKK27107.1 - 0.13 12.8 0.9 0.28 11.7 0.9 1.5 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain zf-Di19 PF05605.12 KKK27107.1 - 0.19 12.1 2.1 0.39 11.0 2.1 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2HE PF16278.5 KKK27107.1 - 0.28 11.6 3.1 27 5.3 3.1 2.6 1 1 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger zf-CCHC_2 PF13696.6 KKK27107.1 - 0.53 10.2 2.1 6.3 6.7 0.3 2.5 2 0 0 2 2 2 0 Zinc knuckle LIM PF00412.22 KKK27107.1 - 1.1 9.5 4.3 28 5.0 0.4 2.4 1 1 1 2 2 2 0 LIM domain FYVE PF01363.21 KKK27107.1 - 5.2 7.3 6.1 10 6.3 6.1 1.5 1 1 0 1 1 1 0 FYVE zinc finger ALG11_N PF15924.5 KKK27108.1 - 2e-78 263.2 0.2 3.6e-78 262.4 0.2 1.4 1 0 0 1 1 1 1 ALG11 mannosyltransferase N-terminus Glycos_transf_1 PF00534.20 KKK27108.1 - 5.2e-13 48.9 0.0 8.7e-13 48.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KKK27108.1 - 1e-07 32.5 0.0 2.6e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KKK27108.1 - 4.1e-05 23.6 0.4 0.00011 22.3 0.1 2.0 2 1 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 KKK27108.1 - 0.0039 17.7 0.1 0.0095 16.4 0.1 1.8 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain MRI PF15325.6 KKK27108.1 - 0.019 16.0 1.4 0.052 14.6 1.4 1.6 1 0 0 1 1 1 0 Modulator of retrovirus infection Pkinase PF00069.25 KKK27109.1 - 1.6e-52 178.5 0.0 4.9e-34 117.9 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KKK27109.1 - 1.3e-25 90.1 0.0 3.8e-24 85.4 0.0 3.0 2 1 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 KKK27109.1 - 7.3e-05 22.8 1.9 0.00038 20.4 0.1 2.5 3 0 0 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KKK27109.1 - 0.00059 19.2 0.0 0.0025 17.2 0.0 1.9 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KKK27109.1 - 0.0012 17.7 0.6 0.0043 15.9 0.0 2.1 2 0 0 2 2 2 1 Fungal protein kinase PsbQ PF05757.11 KKK27110.1 - 0.04 13.7 1.9 0.17 11.6 1.9 2.1 1 0 0 1 1 1 0 Oxygen evolving enhancer protein 3 (PsbQ) Halogen_Hydrol PF10112.9 KKK27110.1 - 0.14 12.2 0.0 0.28 11.2 0.0 1.4 1 0 0 1 1 1 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein AMP-binding PF00501.28 KKK27111.1 - 4.1e-96 322.2 0.0 4.8e-96 321.9 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KKK27111.1 - 5.7e-11 43.2 0.1 1.4e-10 42.0 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DLH PF01738.18 KKK27112.1 - 1.5e-06 28.0 0.0 2.6e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family PMP1_2 PF08114.11 KKK27114.1 - 0.27 11.0 4.2 1.1 9.0 0.4 2.9 2 0 0 2 2 2 0 ATPase proteolipid family Pyr_redox_3 PF13738.6 KKK27115.1 - 3.3e-12 46.3 0.0 6.1e-12 45.4 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KKK27115.1 - 2.4e-11 43.4 0.0 1.5e-09 37.4 0.0 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 KKK27115.1 - 9.3e-10 38.2 0.0 2.8e-09 36.6 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KKK27115.1 - 2.2e-08 33.0 0.0 3.5e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 KKK27115.1 - 0.0019 18.4 0.0 0.0048 17.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KKK27115.1 - 0.0082 15.4 0.1 0.016 14.4 0.1 1.5 1 0 0 1 1 1 1 Thi4 family zf-C2H2 PF00096.26 KKK27117.1 - 5.7e-09 36.0 10.9 6.1e-06 26.4 0.6 3.0 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KKK27117.1 - 4.1e-08 33.3 10.7 8.1e-06 26.0 2.7 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KKK27117.1 - 4.4e-06 27.1 8.9 0.00049 20.7 0.6 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KKK27117.1 - 5.8e-05 22.7 7.4 0.0093 15.7 0.2 2.8 2 0 0 2 2 2 2 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 KKK27117.1 - 0.0013 19.0 4.1 0.018 15.3 0.1 2.3 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KKK27117.1 - 0.0079 16.2 5.8 0.92 9.6 0.3 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2HE PF16278.5 KKK27117.1 - 0.058 13.8 8.8 1.6 9.3 1.0 2.3 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger DUF3295 PF11702.8 KKK27118.1 - 8.7e-190 632.3 30.0 1e-189 632.1 30.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3295) DUF1752 PF08550.10 KKK27118.1 - 5.2e-12 45.4 2.6 1.3e-11 44.1 2.6 1.8 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) TFIIA PF03153.13 KKK27118.1 - 3.8 7.4 14.3 0.082 12.9 5.8 2.0 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF1479 PF07350.12 KKK27119.1 - 1.1e-170 567.9 0.0 1.3e-170 567.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) EMC1_C PF07774.13 KKK27120.1 - 2.5e-77 259.3 0.0 9.5e-77 257.5 0.0 2.0 2 0 0 2 2 2 1 ER membrane protein complex subunit 1, C-terminal PQQ_2 PF13360.6 KKK27120.1 - 9.7e-25 87.5 11.3 2.2e-22 79.8 1.8 3.2 2 1 0 2 2 2 2 PQQ-like domain PQQ PF01011.21 KKK27120.1 - 2.2e-09 36.8 4.5 0.075 13.0 0.2 5.8 6 0 0 6 6 6 2 PQQ enzyme repeat PQQ_3 PF13570.6 KKK27120.1 - 0.0017 18.8 1.1 0.24 11.9 0.0 4.4 3 1 0 3 3 3 1 PQQ-like domain EXS PF03124.14 KKK27121.1 - 7.3e-101 337.8 33.2 9.6e-101 337.4 33.2 1.1 1 0 0 1 1 1 1 EXS family SPX PF03105.19 KKK27121.1 - 2e-75 255.1 12.3 2e-75 255.1 12.3 1.8 2 0 0 2 2 2 1 SPX domain BLI1 PF17324.2 KKK27121.1 - 0.094 13.4 0.5 0.21 12.2 0.5 1.5 1 0 0 1 1 1 0 BLOC-1 interactor 1 Rad60-SLD_2 PF13881.6 KKK27122.1 - 4.6e-12 46.0 0.0 7.9e-12 45.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 KKK27122.1 - 0.0012 19.4 0.0 0.0024 18.4 0.0 1.5 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.23 KKK27122.1 - 0.034 13.9 0.0 0.061 13.1 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin family UMP1 PF05348.11 KKK27123.1 - 7.1e-38 129.5 0.0 9.3e-38 129.1 0.0 1.1 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 Ribosom_S12_S23 PF00164.25 KKK27124.1 - 8.2e-30 102.8 0.4 1.2e-29 102.2 0.4 1.2 1 0 0 1 1 1 1 Ribosomal protein S12/S23 adh_short PF00106.25 KKK27125.1 - 6.5e-37 126.9 0.0 9.7e-37 126.3 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KKK27125.1 - 5.5e-31 107.9 0.0 8.1e-31 107.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KKK27125.1 - 7.7e-05 22.7 0.0 0.0025 17.7 0.0 2.1 2 0 0 2 2 2 1 KR domain DUF1776 PF08643.10 KKK27125.1 - 0.024 14.0 0.0 0.045 13.1 0.0 1.4 2 0 0 2 2 2 0 Fungal family of unknown function (DUF1776) Aa_trans PF01490.18 KKK27126.1 - 6.5e-96 321.5 14.7 6.5e-96 321.5 14.7 1.3 2 0 0 2 2 2 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 KKK27126.1 - 4.8e-05 22.6 17.7 4.8e-05 22.6 17.7 1.7 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family Bax1-I PF01027.20 KKK27127.1 - 1.3e-51 175.4 31.0 1.5e-51 175.2 31.0 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Ycf4 PF02392.16 KKK27127.1 - 0.26 10.9 3.2 0.64 9.6 3.2 1.6 1 0 0 1 1 1 0 Ycf4 DUF5504 PF17608.2 KKK27127.1 - 0.37 10.9 16.2 0.025 14.7 6.6 2.2 1 1 1 2 2 2 0 Family of unknown function (DUF5504) SNF2_N PF00176.23 KKK27128.1 - 4.3e-50 170.4 0.0 6.9e-50 169.7 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KKK27128.1 - 2e-09 37.8 0.0 5.6e-09 36.3 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_3 PF13920.6 KKK27128.1 - 9.6e-07 28.6 5.4 1.9e-06 27.7 5.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KKK27128.1 - 0.0013 18.5 5.5 0.0028 17.5 5.5 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KKK27128.1 - 0.0018 18.2 8.1 0.0043 17.0 8.1 1.6 1 0 0 1 1 1 1 zinc-RING finger domain DEAD PF00270.29 KKK27128.1 - 0.03 14.1 0.0 0.074 12.8 0.0 1.6 1 0 0 1 1 1 0 DEAD/DEAH box helicase ERCC3_RAD25_C PF16203.5 KKK27128.1 - 0.035 13.3 0.0 0.068 12.4 0.0 1.4 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase zf-RING_2 PF13639.6 KKK27128.1 - 0.047 14.0 7.0 0.11 12.8 7.0 1.7 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_2 PF13923.6 KKK27128.1 - 0.057 13.3 3.2 0.16 11.8 3.2 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KKK27128.1 - 0.06 13.2 10.0 0.14 12.0 10.0 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) VPS53_C PF16854.5 KKK27128.1 - 0.069 13.0 2.2 0.37 10.6 0.2 2.5 2 0 0 2 2 2 0 Vacuolar protein sorting-associated protein 53 C-terminus zf-RING_UBOX PF13445.6 KKK27128.1 - 0.34 11.0 6.9 0.98 9.5 6.9 1.7 1 0 0 1 1 1 0 RING-type zinc-finger Sod_Cu PF00080.20 KKK27129.1 - 3.8e-47 160.0 3.3 4.4e-47 159.8 3.3 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Chlorovi_GP_rpt PF06598.11 KKK27129.1 - 0.36 10.9 2.9 1.2 9.2 0.3 2.4 2 0 0 2 2 2 0 Chlorovirus glycoprotein repeat SNase PF00565.17 KKK27130.1 - 2.6e-75 249.8 0.0 2e-24 86.2 0.0 5.7 5 0 0 5 5 5 5 Staphylococcal nuclease homologue CRAL_TRIO PF00650.20 KKK27130.1 - 2.4e-24 85.8 0.0 4.2e-24 85.1 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain TUDOR PF00567.24 KKK27130.1 - 1e-23 83.7 0.0 2.4e-23 82.4 0.0 1.7 1 0 0 1 1 1 1 Tudor domain CRAL_TRIO_N PF03765.15 KKK27130.1 - 1.1e-08 35.1 0.0 3.6e-08 33.5 0.0 1.9 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain SMN PF06003.12 KKK27130.1 - 0.0016 17.8 0.0 0.0032 16.8 0.0 1.5 1 0 0 1 1 1 1 Survival motor neuron protein (SMN) Agenet PF05641.12 KKK27130.1 - 0.019 15.4 0.7 0.08 13.4 0.1 2.5 2 0 0 2 2 2 0 Agenet domain SPATA48 PF15073.6 KKK27130.1 - 0.1 12.9 0.2 0.31 11.3 0.2 1.8 1 0 0 1 1 1 0 Spermatogenesis-associated protein 48 Beach PF02138.18 KKK27131.1 - 3.4e-121 403.9 0.3 2.8e-120 400.8 0.0 2.2 2 0 0 2 2 2 1 Beige/BEACH domain PH_BEACH PF14844.6 KKK27131.1 - 1.1e-12 47.9 0.0 3.2e-12 46.4 0.0 1.8 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH Laminin_G_3 PF13385.6 KKK27131.1 - 5.3e-07 29.9 0.0 1.1e-06 28.8 0.0 1.4 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily WD40 PF00400.32 KKK27131.1 - 5.5e-07 30.2 0.3 0.091 13.7 0.0 3.5 3 0 0 3 3 3 2 WD domain, G-beta repeat DUF4800 PF16057.5 KKK27131.1 - 0.081 12.2 3.5 0.16 11.2 3.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4800) TAL_FSA PF00923.19 KKK27132.1 - 6.2e-95 317.8 0.2 7.1e-95 317.6 0.2 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase UQ_con PF00179.26 KKK27133.1 - 5.3e-39 133.1 0.0 6.6e-39 132.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KKK27133.1 - 0.034 14.4 0.3 0.068 13.5 0.3 1.7 1 1 0 1 1 1 0 RWD domain UFC1 PF08694.11 KKK27133.1 - 0.088 12.4 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 YL1 PF05764.13 KKK27133.1 - 4.6 7.3 7.1 5.5 7.0 7.1 1.2 1 0 0 1 1 1 0 YL1 nuclear protein Peptidase_S8 PF00082.22 KKK27134.1 - 2.7e-38 131.9 7.5 5.1e-38 131.0 7.5 1.4 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 KKK27134.1 - 4e-19 69.1 0.4 1.6e-18 67.2 0.2 2.0 2 0 0 2 2 2 1 Peptidase inhibitor I9 Ferritin_2 PF13668.6 KKK27135.1 - 2.6e-09 37.4 0.0 3.9e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 Ferritin-like domain ABC_tran PF00005.27 KKK27136.1 - 1.1e-53 181.5 0.0 3.9e-31 108.4 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KKK27136.1 - 5e-50 170.7 22.8 4.6e-33 115.1 6.1 2.9 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.19 KKK27136.1 - 9.1e-08 31.8 0.0 0.0022 17.5 0.0 3.8 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KKK27136.1 - 7.4e-06 26.0 0.1 0.1 12.4 0.0 3.5 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KKK27136.1 - 6.7e-05 22.9 2.6 0.11 12.4 0.1 3.5 3 1 0 3 3 3 2 RsgA GTPase MMR_HSR1 PF01926.23 KKK27136.1 - 9.3e-05 22.5 0.1 0.048 13.8 0.0 2.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_23 PF13476.6 KKK27136.1 - 9.4e-05 23.0 7.4 0.0018 18.8 0.1 3.1 3 0 0 3 3 2 2 AAA domain AAA_16 PF13191.6 KKK27136.1 - 0.00097 19.6 1.0 1.7 9.0 0.2 3.5 3 1 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 KKK27136.1 - 0.001 19.4 1.8 1.6 9.0 0.1 3.4 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KKK27136.1 - 0.0028 17.3 0.1 0.36 10.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KKK27136.1 - 0.0031 17.2 0.4 3.1 7.6 0.1 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF87 PF01935.17 KKK27136.1 - 0.0037 17.4 2.0 0.042 13.9 0.8 2.9 2 1 0 2 2 2 1 Helicase HerA, central domain AAA PF00004.29 KKK27136.1 - 0.0062 17.0 1.1 0.7 10.3 0.1 3.3 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 KKK27136.1 - 0.0062 16.3 0.4 1.4 8.7 0.0 3.0 3 0 0 3 3 3 1 IstB-like ATP binding protein Zeta_toxin PF06414.12 KKK27136.1 - 0.01 15.1 0.5 1.3 8.3 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin T2SSE PF00437.20 KKK27136.1 - 0.014 14.5 0.0 0.15 11.1 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_7 PF12775.7 KKK27136.1 - 0.042 13.4 0.1 8.3 5.9 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_18 PF13238.6 KKK27136.1 - 0.081 13.5 0.4 18 5.9 0.0 3.1 3 0 0 3 3 2 0 AAA domain RNA_helicase PF00910.22 KKK27136.1 - 0.12 12.7 0.1 23 5.4 0.0 2.8 2 0 0 2 2 2 0 RNA helicase Adeno_IVa2 PF02456.15 KKK27136.1 - 0.16 10.7 0.2 0.47 9.2 0.0 1.7 2 0 0 2 2 2 0 Adenovirus IVa2 protein AAA_15 PF13175.6 KKK27136.1 - 0.17 11.5 2.0 0.66 9.6 0.0 2.7 3 0 0 3 3 2 0 AAA ATPase domain TrwB_AAD_bind PF10412.9 KKK27136.1 - 0.27 10.1 2.4 1.3 7.8 0.2 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain cobW PF02492.19 KKK27136.1 - 0.42 10.2 1.7 5.2 6.6 0.2 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 KKK27136.1 - 0.62 10.0 2.6 3.8 7.4 0.3 2.4 2 0 0 2 2 2 0 NACHT domain PAT1 PF09770.9 KKK27137.1 - 0 1185.1 0.5 0 1184.9 0.5 1.1 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Erf4 PF10256.9 KKK27137.1 - 0.13 12.4 0.0 1.5 8.9 0.0 2.4 2 0 0 2 2 2 0 Golgin subfamily A member 7/ERF4 family Glyco_transf_15 PF01793.16 KKK27138.1 - 9.1e-125 416.2 8.4 1.1e-124 415.9 8.4 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase SUV3_C PF12513.8 KKK27139.1 - 2e-16 59.6 0.1 4.2e-16 58.6 0.1 1.6 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.31 KKK27139.1 - 5.7e-11 42.7 0.0 1.9e-10 41.0 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Suv3_C_1 PF18147.1 KKK27139.1 - 7.6e-06 25.7 0.1 7.6e-06 25.7 0.1 1.9 2 0 0 2 2 2 1 Suv3 C-terminal domain 1 DUF4771 PF15995.5 KKK27139.1 - 0.012 15.8 0.5 0.029 14.6 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4771) TK PF00265.18 KKK27139.1 - 0.13 12.1 0.0 0.54 10.1 0.0 2.0 3 0 0 3 3 3 0 Thymidine kinase DUF3338 PF11819.8 KKK27139.1 - 1 9.3 5.6 0.25 11.3 1.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3338) Sec1 PF00995.23 KKK27140.1 - 2.1e-112 377.3 0.0 2.8e-112 376.9 0.0 1.1 1 0 0 1 1 1 1 Sec1 family Glycos_transf_2 PF00535.26 KKK27140.1 - 0.13 12.1 0.5 2.7 7.8 0.0 2.4 2 0 0 2 2 2 0 Glycosyl transferase family 2 DEC-1_N PF04625.13 KKK27140.1 - 7.3 5.5 11.1 5.7 5.8 9.1 1.7 2 0 0 2 2 2 0 DEC-1 protein, N-terminal region G-patch PF01585.23 KKK27141.1 - 1.8e-05 24.6 0.1 3.6e-05 23.5 0.1 1.5 1 0 0 1 1 1 1 G-patch domain zf-U1 PF06220.12 KKK27141.1 - 0.26 11.1 1.9 14 5.5 0.1 2.4 2 0 0 2 2 2 0 U1 zinc finger adh_short PF00106.25 KKK27142.1 - 1.9e-14 53.6 0.0 6.1e-14 51.9 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 KKK27142.1 - 5.1e-06 26.5 0.0 8.9e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 KKK27142.1 - 1.7e-05 24.5 0.0 3e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.15 KKK27142.1 - 0.043 12.9 0.1 0.062 12.4 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Epimerase PF01370.21 KKK27142.1 - 0.13 11.7 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KKK27143.1 - 9.2e-50 169.9 0.0 2.7e-49 168.4 0.0 1.7 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KKK27143.1 - 3.3e-48 164.2 0.0 5.1e-48 163.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KKK27143.1 - 8.4e-16 57.8 0.0 1.4e-15 57.1 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 KKK27143.1 - 3.7e-12 46.0 0.0 5.4e-11 42.2 0.0 2.2 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 KKK27143.1 - 9.7e-12 44.6 0.0 1.4e-11 44.0 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.25 KKK27143.1 - 1.3e-11 44.3 0.0 3.8e-11 42.8 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 KKK27143.1 - 6.9e-07 29.4 0.0 1.4e-06 28.3 0.0 1.5 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 KKK27143.1 - 1.7e-05 24.5 0.1 3e-05 23.7 0.1 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 KKK27143.1 - 0.00012 22.1 0.0 0.00018 21.4 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 KKK27143.1 - 0.00025 20.3 0.2 0.056 12.6 0.0 2.3 1 1 1 2 2 2 2 Male sterility protein NmrA PF05368.13 KKK27143.1 - 0.0077 15.8 0.0 0.037 13.6 0.0 1.9 2 0 0 2 2 2 1 NmrA-like family Cys_Met_Meta_PP PF01053.20 KKK27143.1 - 0.11 11.0 0.1 0.54 8.7 0.0 1.9 2 0 0 2 2 2 0 Cys/Met metabolism PLP-dependent enzyme 3HCDH_N PF02737.18 KKK27143.1 - 0.15 11.9 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Sugar_tr PF00083.24 KKK27144.1 - 5.9e-75 252.8 19.0 2.4e-74 250.9 19.0 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKK27144.1 - 4.3e-22 78.5 11.0 1.8e-20 73.2 9.7 2.2 2 1 0 2 2 2 2 Major Facilitator Superfamily Ribosomal_L44 PF00935.19 KKK27145.1 - 8.3e-36 122.3 12.4 1.6e-35 121.4 12.4 1.5 1 0 0 1 1 1 1 Ribosomal protein L44 TBCA PF02970.16 KKK27146.1 - 4.8e-23 81.3 7.8 5.9e-23 81.0 7.8 1.2 1 0 0 1 1 1 1 Tubulin binding cofactor A T3SSipB PF16535.5 KKK27146.1 - 0.0028 18.1 1.6 0.0028 18.1 1.6 2.0 1 1 1 2 2 2 1 Type III cell invasion protein SipB THOC7 PF05615.13 KKK27147.1 - 3.2e-45 153.6 2.6 3.2e-45 153.6 2.6 2.1 1 1 1 2 2 2 1 Tho complex subunit 7 Mod_r PF07200.13 KKK27147.1 - 0.0056 16.8 11.3 0.0097 16.0 11.3 1.4 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein FapA PF03961.13 KKK27147.1 - 0.27 9.8 2.7 0.39 9.3 2.7 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A DivIC PF04977.15 KKK27147.1 - 5 7.0 9.4 0.94 9.3 3.5 2.7 1 1 1 2 2 2 0 Septum formation initiator FUSC PF04632.12 KKK27147.1 - 7.1 5.0 8.4 9.4 4.6 8.4 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Elongin_A PF06881.11 KKK27148.1 - 1.8e-28 99.2 0.9 2.6e-28 98.6 0.1 1.7 2 0 0 2 2 2 1 RNA polymerase II transcription factor SIII (Elongin) subunit A Band_7 PF01145.25 KKK27149.1 - 2.5e-14 53.7 0.1 2.5e-14 53.7 0.1 2.3 2 0 0 2 2 2 1 SPFH domain / Band 7 family Atg14 PF10186.9 KKK27149.1 - 0.69 8.9 9.9 1.1 8.3 9.9 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DBD_Tnp_Mut PF03108.15 KKK27150.1 - 7.1e-10 38.7 0.4 1.3e-09 37.9 0.4 1.4 1 0 0 1 1 1 1 MuDR family transposase Fungal_trans PF04082.18 KKK27151.1 - 2.8e-07 29.8 0.0 6.1e-07 28.7 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK27151.1 - 0.0029 17.7 2.5 0.0056 16.8 2.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sel1 PF08238.12 KKK27152.1 - 9.9e-38 127.7 43.1 1e-08 35.5 0.1 8.1 8 0 0 8 8 8 7 Sel1 repeat TPR_20 PF14561.6 KKK27152.1 - 0.041 14.2 0.7 1.5 9.2 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 KKK27152.1 - 3 8.7 11.5 19 6.2 1.2 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat AAA_12 PF13087.6 KKK27153.1 - 3.1e-39 134.7 0.0 5.1e-39 134.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KKK27153.1 - 4e-06 26.8 0.0 0.021 14.6 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 KKK27153.1 - 6.7e-05 23.2 0.0 0.0038 17.6 0.0 3.0 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KKK27153.1 - 0.031 14.0 0.0 1 9.0 0.0 2.5 2 1 0 2 2 2 0 AAA domain ATPase PF06745.13 KKK27153.1 - 0.057 12.8 0.0 0.097 12.0 0.0 1.3 1 0 0 1 1 1 0 KaiC Viral_helicase1 PF01443.18 KKK27153.1 - 0.098 12.4 0.3 40 3.8 0.0 3.7 4 1 1 5 5 5 0 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.9 KKK27153.1 - 0.23 10.7 0.0 0.43 9.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) FAD_binding_3 PF01494.19 KKK27154.1 - 4.1e-73 246.6 0.3 4e-72 243.4 0.3 2.0 1 1 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 KKK27154.1 - 2.8e-29 102.3 0.0 5.3e-29 101.4 0.0 1.5 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain SE PF08491.10 KKK27154.1 - 0.0048 16.0 0.0 0.018 14.1 0.0 1.8 2 0 0 2 2 2 1 Squalene epoxidase Pyr_redox_2 PF07992.14 KKK27154.1 - 0.048 12.9 0.1 0.11 11.7 0.1 1.7 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lactamase_B PF00753.27 KKK27154.1 - 0.051 13.6 0.1 0.35 10.8 0.1 2.2 1 1 0 1 1 1 0 Metallo-beta-lactamase superfamily Lycopene_cycl PF05834.12 KKK27154.1 - 0.11 11.5 0.1 0.21 10.6 0.1 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_binding_8 PF13450.6 KKK27154.1 - 0.11 12.7 0.1 0.38 11.0 0.1 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KKK27154.1 - 0.13 10.9 0.0 0.21 10.3 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_8 PF13450.6 KKK27155.1 - 3.3e-12 46.4 0.0 6.8e-12 45.4 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.19 KKK27155.1 - 5.4e-12 44.9 3.3 1.8e-11 43.2 0.9 2.5 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KKK27155.1 - 3.3e-10 39.7 0.0 4.4e-08 32.7 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KKK27155.1 - 5.1e-06 25.9 0.7 0.001 18.3 0.0 3.2 3 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 KKK27155.1 - 3.1e-05 23.7 0.6 0.0045 16.6 0.2 2.4 2 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KKK27155.1 - 0.00043 19.6 0.0 0.01 15.1 0.0 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KKK27155.1 - 0.0019 17.5 0.0 0.14 11.4 0.0 2.4 2 0 0 2 2 2 1 Thi4 family NAD_binding_9 PF13454.6 KKK27155.1 - 0.0047 16.9 1.7 0.022 14.7 0.0 2.9 3 1 0 3 3 3 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 KKK27155.1 - 0.23 10.5 0.0 0.36 9.8 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain DUF1033 PF06279.11 KKK27155.1 - 4.8 7.4 6.3 0.67 10.1 0.9 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1033) MPC PF03650.13 KKK27156.1 - 8.6e-50 167.5 0.2 1.1e-49 167.1 0.2 1.1 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers DUF1512 PF07431.12 KKK27156.1 - 0.088 11.8 0.1 0.11 11.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1512) MFS_1 PF07690.16 KKK27157.1 - 1e-42 146.3 23.5 1e-42 146.3 23.5 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KKK27157.1 - 1.3e-11 44.0 1.6 1.3e-11 44.0 1.6 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter OATP PF03137.20 KKK27157.1 - 0.27 9.5 3.2 1.9 6.7 0.3 2.2 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Fungal_trans PF04082.18 KKK27158.1 - 1.2e-09 37.6 1.8 2.1e-09 36.8 1.8 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2_4 PF13894.6 KKK27158.1 - 0.0075 17.0 3.7 0.056 14.3 3.7 2.6 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2 PF00096.26 KKK27158.1 - 0.026 15.0 4.4 0.1 13.1 4.4 2.1 1 0 0 1 1 1 0 Zinc finger, C2H2 type Glyco_hydro_28 PF00295.17 KKK27159.1 - 2.2e-49 168.3 7.7 3.8e-49 167.5 7.6 1.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 28 LigB PF02900.18 KKK27160.1 - 1.2e-33 116.4 0.0 1.4e-33 116.2 0.0 1.0 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase L51_S25_CI-B8 PF05047.16 KKK27161.1 - 9.2e-10 38.3 0.0 1.2e-09 38.0 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain CBP4 PF07960.11 KKK27162.1 - 1.7e-30 105.5 5.4 3.7e-30 104.4 5.4 1.4 1 1 0 1 1 1 1 CBP4 Ank_2 PF12796.7 KKK27163.1 - 8.4e-153 497.4 0.6 3.4e-18 66.0 0.0 12.2 2 2 11 13 13 13 13 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KKK27163.1 - 8.8e-109 354.6 0.1 4.6e-12 46.2 0.0 16.2 4 3 12 18 18 18 18 Ankyrin repeats (many copies) Ank PF00023.30 KKK27163.1 - 1.4e-98 319.4 1.1 0.00028 21.2 0.0 22.9 23 0 0 23 23 23 22 Ankyrin repeat Ank_3 PF13606.6 KKK27163.1 - 8.1e-98 308.5 0.1 0.00012 22.2 0.0 23.1 23 0 0 23 23 23 22 Ankyrin repeat Ank_5 PF13857.6 KKK27163.1 - 3e-93 304.6 13.8 3.8e-10 39.8 0.0 17.5 4 2 11 18 18 18 18 Ankyrin repeats (many copies) VWA_3_C PF18571.1 KKK27163.1 - 0.035 14.0 0.7 1.3e+02 2.6 0.0 6.2 7 0 0 7 7 7 0 von Willebrand factor type A C-terminal domain DUF3718 PF12514.8 KKK27163.1 - 0.15 12.3 0.2 3.2 8.0 0.0 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF3718) Synaptobrevin PF00957.21 KKK27164.1 - 2.1e-31 107.5 0.7 2.4e-31 107.3 0.7 1.0 1 0 0 1 1 1 1 Synaptobrevin Prominin PF05478.11 KKK27164.1 - 0.0098 13.9 0.1 0.012 13.6 0.1 1.1 1 0 0 1 1 1 1 Prominin AKNA PF12443.8 KKK27164.1 - 0.14 12.8 0.1 0.62 10.7 0.0 1.8 1 1 1 2 2 2 0 AT-hook-containing transcription factor NAT PF04768.13 KKK27165.1 - 5.5e-56 188.9 0.1 1.2e-55 187.8 0.0 1.6 2 0 0 2 2 2 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase Semialdhyde_dh PF01118.24 KKK27165.1 - 6.6e-31 107.3 0.0 1.8e-30 105.9 0.0 1.8 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain AA_kinase PF00696.28 KKK27165.1 - 6.5e-29 101.2 0.0 1.4e-28 100.1 0.0 1.5 1 0 0 1 1 1 1 Amino acid kinase family DapB_N PF01113.20 KKK27165.1 - 0.074 13.2 0.0 0.25 11.5 0.0 2.0 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus PDH PF02153.17 KKK27166.1 - 5.3e-15 55.1 0.0 7.5e-15 54.6 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydrogenase F420_oxidored PF03807.17 KKK27166.1 - 1.5e-06 28.7 0.0 3.1e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 KKK27166.1 - 1e-05 25.8 0.0 1.7e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.19 KKK27166.1 - 0.0026 17.1 0.0 0.0047 16.3 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.16 KKK27166.1 - 0.0044 16.7 0.0 0.009 15.7 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 KKK27166.1 - 0.032 14.1 0.0 0.06 13.2 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.18 KKK27166.1 - 0.035 14.4 0.0 0.14 12.4 0.0 2.0 2 0 0 2 2 2 0 TrkA-N domain DUF2185 PF09951.9 KKK27166.1 - 0.051 13.4 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2185) PocR PF10114.9 KKK27166.1 - 0.11 12.3 0.0 14 5.5 0.0 2.5 3 0 0 3 3 3 0 Sensory domain found in PocR IlvN PF07991.12 KKK27166.1 - 0.16 11.5 0.0 0.27 10.8 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Ribosomal_S11 PF00411.19 KKK27167.1 - 5.3e-27 94.4 0.2 5.9e-27 94.3 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 RICTOR_N PF14664.6 KKK27168.1 - 1.9e-129 431.9 1.0 4.7e-129 430.6 0.4 2.0 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, N-term RasGEF_N_2 PF14663.6 KKK27168.1 - 3e-39 133.8 0.1 6.7e-36 123.0 0.0 3.4 3 0 0 3 3 3 2 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_M PF14666.6 KKK27168.1 - 4.7e-39 132.4 1.4 2.3e-34 117.3 0.1 5.1 5 0 0 5 5 5 1 Rapamycin-insensitive companion of mTOR, middle domain RICTOR_V PF14668.6 KKK27168.1 - 1e-25 89.8 4.9 2.2e-25 88.7 0.1 3.9 6 0 0 6 6 6 1 Rapamycin-insensitive companion of mTOR, domain 5 HR1 PF02185.16 KKK27168.1 - 2.3e-16 59.7 7.3 5.7e-16 58.4 7.3 1.7 1 0 0 1 1 1 1 Hr1 repeat Uds1 PF15456.6 KKK27168.1 - 0.074 13.2 5.7 0.18 12.0 5.7 1.6 1 0 0 1 1 1 0 Up-regulated During Septation Arm PF00514.23 KKK27168.1 - 0.25 11.5 3.5 14 5.9 0.1 3.3 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat CDH-cyt PF16010.5 KKK27169.1 - 7.1e-20 71.4 0.0 1.3e-19 70.6 0.0 1.3 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase Cytochrom_B561 PF03188.16 KKK27169.1 - 1.1e-06 28.9 4.6 2.2e-06 27.8 4.6 1.5 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DUF1616 PF07760.11 KKK27169.1 - 0.11 11.9 1.2 0.22 10.9 1.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1616) Phage_holin_3_6 PF07332.11 KKK27169.1 - 1.9 8.5 6.3 23 5.1 4.3 2.6 2 1 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III EST1_DNA_bind PF10373.9 KKK27170.1 - 2.2e-70 237.4 0.1 4.9e-70 236.2 0.1 1.5 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain EST1 PF10374.9 KKK27170.1 - 4.1e-24 85.8 0.2 1.2e-23 84.2 0.1 1.9 2 0 0 2 2 2 1 Telomerase activating protein Est1 ATG101 PF07855.12 KKK27171.1 - 6.5e-54 182.1 0.0 7.5e-54 181.9 0.0 1.0 1 0 0 1 1 1 1 Autophagy-related protein 101 PfkB PF00294.24 KKK27172.1 - 3.4e-70 236.7 0.1 3.9e-70 236.5 0.1 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 KKK27172.1 - 0.014 14.7 0.0 0.029 13.8 0.0 1.4 1 0 0 1 1 1 0 Phosphomethylpyrimidine kinase Peroxin-3 PF04882.12 KKK27173.1 - 7.8e-163 542.8 0.3 9.2e-163 542.6 0.3 1.0 1 0 0 1 1 1 1 Peroxin-3 MFS_1 PF07690.16 KKK27174.1 - 3.1e-35 121.7 29.5 5e-35 121.1 29.5 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Wzy_C PF04932.15 KKK27174.1 - 1.7 8.2 8.2 0.36 10.5 2.2 2.5 2 0 0 2 2 2 0 O-Antigen ligase TB2_DP1_HVA22 PF03134.19 KKK27175.1 - 1.4e-27 95.4 7.8 2.4e-27 94.6 7.8 1.4 1 0 0 1 1 1 1 TB2/DP1, HVA22 family DUF1614 PF07758.11 KKK27175.1 - 0.032 14.2 0.3 0.039 14.0 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1614) Fungal_trans PF04082.18 KKK27176.1 - 9.1e-15 54.4 1.1 9.1e-15 54.4 1.1 2.0 2 1 0 2 2 2 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 KKK27176.1 - 2.6e-11 43.3 11.1 1.4e-05 25.3 2.5 3.1 3 0 0 3 3 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KKK27176.1 - 6e-09 36.0 7.9 0.00063 20.4 2.0 3.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KKK27176.1 - 5.6e-08 32.9 2.4 5.6e-08 32.9 2.4 3.7 4 0 0 4 4 3 1 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KKK27176.1 - 5.5e-06 26.5 1.2 0.06 13.7 0.5 2.7 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.6 KKK27176.1 - 0.00033 20.5 2.4 0.27 11.2 0.3 3.0 2 0 0 2 2 2 2 zinc-finger of a C2HC-type zf-C2H2_6 PF13912.6 KKK27176.1 - 0.0029 17.6 7.0 0.51 10.4 2.2 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 KKK27176.1 - 0.0079 16.6 3.2 1.5 9.3 0.7 2.8 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2HE PF16278.5 KKK27176.1 - 0.025 15.0 1.8 0.025 15.0 1.8 2.3 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-BED PF02892.15 KKK27176.1 - 1.2 9.2 4.9 5.5 7.1 1.8 2.7 1 1 1 2 2 2 0 BED zinc finger gag_pre-integrs PF13976.6 KKK27176.1 - 2.6 8.0 5.3 2.3 8.2 0.9 2.5 1 1 1 2 2 2 0 GAG-pre-integrase domain zf-H2C2_5 PF13909.6 KKK27176.1 - 8.9 6.2 6.9 1.6 8.6 2.2 2.3 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 KKK27177.1 - 0.00074 19.8 2.1 0.037 14.5 0.3 2.9 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KKK27177.1 - 0.64 11.0 0.2 0.64 11.0 0.2 2.9 3 0 0 3 3 3 0 C2H2-type zinc finger Pkinase PF00069.25 KKK27178.1 - 8.7e-69 231.8 0.0 8e-68 228.6 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK27178.1 - 3e-49 167.6 0.0 1.8e-47 161.8 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Ras_bdg_2 PF14847.6 KKK27178.1 - 5.7e-28 97.2 0.0 1e-27 96.4 0.0 1.4 1 0 0 1 1 1 1 Ras-binding domain of Byr2 SAM_1 PF00536.30 KKK27178.1 - 3.2e-14 53.1 0.1 8.3e-14 51.8 0.1 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KKK27178.1 - 2e-11 43.8 0.1 5.4e-11 42.4 0.1 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Kinase-like PF14531.6 KKK27178.1 - 2.4e-08 33.7 0.0 4e-05 23.1 0.0 2.4 2 0 0 2 2 2 2 Kinase-like RA PF00788.23 KKK27178.1 - 8.6e-07 29.5 0.0 1.5e-06 28.7 0.0 1.4 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Pkinase_fungal PF17667.1 KKK27178.1 - 0.0011 17.9 0.0 0.0019 17.1 0.0 1.5 1 1 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KKK27178.1 - 0.046 13.1 0.0 0.094 12.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SAM_4 PF18017.1 KKK27178.1 - 0.055 13.5 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) MSA-2c PF12238.8 KKK27178.1 - 0.58 10.1 0.0 0.58 10.1 0.0 2.3 3 0 0 3 3 3 0 Merozoite surface antigen 2c SNF2_N PF00176.23 KKK27179.1 - 2.2e-73 247.0 0.7 2.2e-73 247.0 0.7 2.2 2 0 0 2 2 2 1 SNF2 family N-terminal domain Bromodomain PF00439.25 KKK27179.1 - 1.6e-25 89.0 1.2 7.4e-25 86.8 0.4 2.6 2 1 0 2 2 2 1 Bromodomain Helicase_C PF00271.31 KKK27179.1 - 4e-20 72.2 1.6 2.8e-18 66.3 0.0 3.6 3 1 1 4 4 4 1 Helicase conserved C-terminal domain HSA PF07529.13 KKK27179.1 - 3.8e-19 68.8 17.4 3.8e-19 68.8 17.4 3.2 3 0 0 3 3 3 1 HSA SnAC PF14619.6 KKK27179.1 - 4.9e-16 59.1 2.5 4.9e-16 59.1 2.5 3.4 3 0 0 3 3 3 1 Snf2-ATP coupling, chromatin remodelling complex QLQ PF08880.11 KKK27179.1 - 4.4e-14 51.9 3.9 1.1e-13 50.7 3.9 1.8 1 0 0 1 1 1 1 QLQ ResIII PF04851.15 KKK27179.1 - 3.8e-09 36.8 0.0 3.8e-09 36.8 0.0 2.4 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit BAR PF03114.18 KKK27180.1 - 2.4e-49 168.2 8.2 3.1e-49 167.8 8.2 1.1 1 0 0 1 1 1 1 BAR domain BAR_2 PF10455.9 KKK27180.1 - 1.8e-07 30.6 3.6 2.3e-07 30.3 3.6 1.2 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking Apo-CIII PF05778.12 KKK27180.1 - 0.011 15.3 0.1 0.031 13.9 0.1 1.7 1 0 0 1 1 1 0 Apolipoprotein CIII (Apo-CIII) Ribosomal_S10 PF00338.22 KKK27180.1 - 0.042 14.1 0.4 0.11 12.8 0.4 1.7 1 0 0 1 1 1 0 Ribosomal protein S10p/S20e APG6_N PF17675.1 KKK27180.1 - 3.9 8.0 13.1 12 6.4 13.1 1.9 1 1 0 1 1 1 0 Apg6 coiled-coil region Ada_Zn_binding PF02805.16 KKK27181.1 - 1.1e-30 105.4 5.1 1.9e-30 104.6 5.1 1.4 1 0 0 1 1 1 1 Metal binding domain of Ada HTH_AraC PF00165.23 KKK27181.1 - 1.9e-07 31.0 0.0 5.1e-07 29.6 0.0 1.7 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_18 PF12833.7 KKK27181.1 - 0.00062 20.0 0.0 0.0013 18.9 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain Ribosomal_L2_C PF03947.18 KKK27182.1 - 9.6e-32 109.8 6.7 9.8e-30 103.3 6.7 2.4 1 1 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 KKK27182.1 - 9.8e-15 54.3 0.1 2.5e-14 53.0 0.1 1.7 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain WHIM1 PF15612.6 KKK27183.1 - 1e-06 28.1 0.0 2.4e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 YL1 PF05764.13 KKK27183.1 - 8.7 6.4 14.4 1 9.4 3.9 2.6 2 0 0 2 2 2 0 YL1 nuclear protein DUF1770 PF08589.10 KKK27184.1 - 3.3e-21 76.1 1.7 9.1e-21 74.7 0.7 2.1 2 1 0 2 2 2 1 Fungal protein of unknown function (DUF1770) Aminotran_1_2 PF00155.21 KKK27185.1 - 1.9e-05 24.1 0.0 2.5e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II RAP1 PF07218.11 KKK27185.1 - 0.034 12.4 6.3 0.034 12.5 6.3 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Ecl1 PF12855.7 KKK27186.1 - 1.2 10.3 7.2 2.5 9.2 7.2 1.5 1 0 0 1 1 1 0 ECL1/2/3 zinc binding proteins ERG4_ERG24 PF01222.17 KKK27187.1 - 2.9e-154 514.0 5.8 3.4e-154 513.8 5.8 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 KKK27187.1 - 5.5e-07 29.3 0.2 1.4e-06 28.0 0.2 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) A_deamin PF02137.18 KKK27188.1 - 3.6e-24 85.8 0.0 8.8e-21 74.7 0.0 2.9 2 1 0 2 2 2 2 Adenosine-deaminase (editase) domain SF3b10 PF07189.11 KKK27189.1 - 2.1e-35 120.7 0.0 2.3e-35 120.5 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) DUF3074 PF11274.8 KKK27190.1 - 9.4e-54 182.2 0.3 9.4e-54 182.2 0.3 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3074) DUF5320 PF17253.2 KKK27190.1 - 5.8 8.1 7.6 43 5.3 2.4 3.0 2 1 0 2 2 2 0 Family of unknown function (DUF5320) Fungal_trans PF04082.18 KKK27192.1 - 2.7e-26 92.2 0.0 4.7e-26 91.4 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK27192.1 - 4.6e-09 36.3 12.1 7.3e-09 35.6 12.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Man-6-P_recep PF02157.15 KKK27193.1 - 9.1e-18 64.3 0.0 1.3e-17 63.8 0.0 1.1 1 0 0 1 1 1 1 Mannose-6-phosphate receptor ATG27 PF09451.10 KKK27193.1 - 5.6e-13 49.4 0.0 1.9e-12 47.6 0.0 1.7 1 1 0 1 1 1 1 Autophagy-related protein 27 CIMR PF00878.18 KKK27193.1 - 6.6e-08 32.7 1.2 0.00016 21.7 0.1 2.4 2 1 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat Vps51 PF08700.11 KKK27194.1 - 2.6e-26 91.5 0.0 5.7e-26 90.4 0.0 1.6 1 0 0 1 1 1 1 Vps51/Vps67 COG5 PF10392.9 KKK27194.1 - 0.0013 18.9 0.0 0.0025 18.0 0.0 1.4 1 0 0 1 1 1 1 Golgi transport complex subunit 5 THUMP PF02926.17 KKK27194.1 - 0.05 13.7 0.3 0.078 13.1 0.3 1.4 1 0 0 1 1 1 0 THUMP domain Dor1 PF04124.12 KKK27194.1 - 0.057 12.1 0.0 0.068 11.8 0.0 1.2 1 0 0 1 1 1 0 Dor1-like family HeLo PF14479.6 KKK27194.1 - 0.071 12.9 0.3 0.11 12.3 0.3 1.6 1 1 0 1 1 1 0 Prion-inhibition and propagation FlgN PF05130.12 KKK27194.1 - 0.82 10.2 4.1 22 5.5 0.6 2.6 1 1 1 2 2 2 0 FlgN protein Glyco_hydro_5_C PF18564.1 KKK27195.1 - 5.6e-20 71.7 0.0 1.3e-19 70.5 0.0 1.7 1 0 0 1 1 1 1 Glycoside hydrolase family 5 C-terminal domain Cellulase PF00150.18 KKK27195.1 - 7.5e-10 38.7 1.2 2.8e-08 33.6 0.8 2.7 2 1 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) RMI1_N PF08585.12 KKK27196.1 - 7.8e-61 205.6 0.0 8.9e-61 205.4 0.0 1.0 1 0 0 1 1 1 1 RecQ mediated genome instability protein TPR_16 PF13432.6 KKK27197.1 - 5.8e-24 84.5 31.6 8.6e-05 23.1 0.0 11.5 10 2 1 12 12 12 5 Tetratricopeptide repeat TPR_17 PF13431.6 KKK27197.1 - 5.4e-22 76.5 7.0 0.75 10.3 0.0 13.3 14 0 0 14 14 14 5 Tetratricopeptide repeat TPR_2 PF07719.17 KKK27197.1 - 1.1e-19 68.9 48.0 0.059 13.5 0.2 15.6 19 0 0 19 19 16 6 Tetratricopeptide repeat TPR_1 PF00515.28 KKK27197.1 - 1.8e-17 62.3 31.5 0.017 14.9 0.0 14.6 16 2 1 17 17 16 5 Tetratricopeptide repeat TPR_8 PF13181.6 KKK27197.1 - 6.6e-17 60.3 23.7 0.4 11.0 0.1 12.9 14 0 0 14 14 12 4 Tetratricopeptide repeat TPR_14 PF13428.6 KKK27197.1 - 1e-16 60.2 35.7 0.03 15.1 0.0 15.7 15 5 5 20 20 15 3 Tetratricopeptide repeat TPR_19 PF14559.6 KKK27197.1 - 5.1e-15 55.7 14.8 0.024 15.2 0.0 10.7 10 2 2 12 12 10 3 Tetratricopeptide repeat TPR_12 PF13424.6 KKK27197.1 - 4.9e-13 49.2 34.1 8.9e-07 29.1 0.8 10.8 8 4 1 12 12 11 3 Tetratricopeptide repeat TPR_11 PF13414.6 KKK27197.1 - 2.9e-12 46.1 19.8 0.0078 15.9 0.0 10.5 11 0 0 11 11 11 4 TPR repeat TPR_7 PF13176.6 KKK27197.1 - 1.3e-08 34.2 16.0 0.00096 19.0 0.0 9.9 12 1 0 12 12 11 2 Tetratricopeptide repeat TPR_6 PF13174.6 KKK27197.1 - 7.4e-08 32.6 17.2 0.18 12.5 0.1 10.2 11 0 0 11 11 10 2 Tetratricopeptide repeat TPR_10 PF13374.6 KKK27197.1 - 2.4e-06 27.2 12.8 0.026 14.4 0.1 8.6 10 0 0 10 10 9 1 Tetratricopeptide repeat TPR_22 PF18833.1 KKK27197.1 - 0.0011 19.0 0.0 0.0036 17.4 0.0 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat Coatomer_E PF04733.14 KKK27197.1 - 0.0016 17.9 0.1 0.022 14.2 0.0 2.6 2 0 0 2 2 2 1 Coatomer epsilon subunit DUF2225 PF09986.9 KKK27197.1 - 0.0047 16.7 1.0 0.42 10.3 0.2 3.4 3 0 0 3 3 3 1 Uncharacterized protein conserved in bacteria (DUF2225) TPR_9 PF13371.6 KKK27197.1 - 0.0093 16.1 7.8 1.7 8.9 0.0 6.0 5 1 1 6 6 5 1 Tetratricopeptide repeat Tcf25 PF04910.14 KKK27197.1 - 0.028 13.5 0.1 0.72 8.9 0.0 2.6 2 0 0 2 2 2 0 Transcriptional repressor TCF25 FAT PF02259.23 KKK27197.1 - 0.031 13.5 10.2 1.5 7.9 1.8 4.6 5 0 0 5 5 5 0 FAT domain TPR_4 PF07721.14 KKK27197.1 - 0.052 14.2 9.5 30 5.7 0.0 6.5 6 0 0 6 6 6 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KKK27197.1 - 0.066 13.4 13.8 4.9 7.5 0.0 6.3 6 1 1 7 7 5 0 Anaphase-promoting complex, cyclosome, subunit 3 zf-CCHC PF00098.23 KKK27198.1 - 9.6e-46 151.9 57.6 2.2e-07 30.7 0.9 7.1 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.6 KKK27198.1 - 1e-09 38.0 38.6 0.038 13.7 0.4 7.1 7 0 0 7 7 7 6 Zinc knuckle zf-CCHC_3 PF13917.6 KKK27198.1 - 5.1e-08 32.7 41.6 0.0041 17.0 0.3 7.0 4 2 2 6 6 6 4 Zinc knuckle zf-CCHC_5 PF14787.6 KKK27198.1 - 0.00022 20.8 41.4 0.019 14.6 0.9 7.0 4 2 3 7 7 7 5 GAG-polyprotein viral zinc-finger TFB6 PF17110.5 KKK27199.1 - 2.9e-58 196.4 0.3 4.4e-58 195.8 0.0 1.4 2 0 0 2 2 2 1 Subunit 11 of the general transcription factor TFIIH RRM_Rrp7 PF17799.1 KKK27200.1 - 4.2e-32 111.2 0.0 7.4e-32 110.4 0.0 1.5 1 0 0 1 1 1 1 Rrp7 RRM-like N-terminal domain RRP7 PF12923.7 KKK27200.1 - 5.9e-27 94.2 10.8 5.9e-27 94.2 10.8 2.4 3 0 0 3 3 3 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain Dak1_2 PF13684.6 KKK27200.1 - 0.19 10.8 3.8 1.1 8.3 0.1 2.3 1 1 0 2 2 2 0 Dihydroxyacetone kinase family Rad51 PF08423.11 KKK27201.1 - 1.2e-112 375.4 0.0 1.5e-112 375.0 0.0 1.1 1 0 0 1 1 1 1 Rad51 RecA PF00154.21 KKK27201.1 - 6.2e-12 45.5 0.0 8.4e-12 45.1 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein HHH_5 PF14520.6 KKK27201.1 - 4e-09 36.9 1.1 1.2e-08 35.5 0.4 2.1 2 0 0 2 2 2 1 Helix-hairpin-helix domain ATPase PF06745.13 KKK27201.1 - 4.6e-07 29.4 0.0 1.1e-06 28.1 0.0 1.7 1 1 0 1 1 1 1 KaiC AAA_25 PF13481.6 KKK27201.1 - 0.00012 21.8 0.0 0.00016 21.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 KKK27201.1 - 0.089 12.1 0.0 0.87 8.9 0.0 2.1 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain PAXNEB PF05625.11 KKK27201.1 - 0.2 10.8 0.0 1.2 8.2 0.0 1.9 2 0 0 2 2 2 0 PAXNEB protein DivIVA PF05103.13 KKK27202.1 - 0.0029 17.7 23.0 0.0036 17.4 9.8 3.6 2 1 2 4 4 4 2 DivIVA protein Fib_alpha PF08702.10 KKK27202.1 - 0.51 10.5 10.7 1.4 9.1 0.9 3.0 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Phage_GP20 PF06810.11 KKK27202.1 - 0.67 9.7 9.1 0.48 10.2 1.6 3.0 2 1 1 3 3 3 0 Phage minor structural protein GP20 Methyltransf_16 PF10294.9 KKK27203.1 - 5.9e-16 58.7 0.1 3.2e-09 36.8 0.0 2.1 2 0 0 2 2 2 2 Lysine methyltransferase Methyltransf_25 PF13649.6 KKK27203.1 - 0.00021 21.9 0.1 0.00044 20.9 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KKK27203.1 - 0.00042 19.8 0.0 0.00068 19.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.6 KKK27203.1 - 0.00043 20.2 0.0 0.00074 19.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 KKK27203.1 - 0.0011 18.8 0.0 0.0018 18.1 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein PCMT PF01135.19 KKK27203.1 - 0.0049 16.7 0.0 0.0078 16.0 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Trypan_PARP PF05887.11 KKK27203.1 - 0.0089 16.0 0.5 0.017 15.1 0.5 1.4 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) MTS PF05175.14 KKK27203.1 - 0.009 15.6 0.0 0.015 14.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 KKK27203.1 - 0.03 14.1 0.1 0.081 12.7 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain DUF938 PF06080.12 KKK27203.1 - 0.035 13.8 0.0 0.061 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_12 PF08242.12 KKK27203.1 - 0.05 14.4 0.3 1.3 9.8 0.0 2.7 3 0 0 3 3 3 0 Methyltransferase domain Pro_isomerase PF00160.21 KKK27204.1 - 7.7e-33 114.0 0.0 1.2e-32 113.3 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.22 KKK27204.1 - 6.3e-16 58.0 0.0 1.4e-15 56.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) UDPGP PF01704.18 KKK27205.1 - 2.8e-56 191.0 0.0 3.6e-56 190.6 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.7 KKK27205.1 - 0.0068 16.8 0.0 0.018 15.4 0.0 1.7 2 0 0 2 2 2 1 MobA-like NTP transferase domain DegV PF02645.16 KKK27205.1 - 0.19 11.0 0.2 0.31 10.4 0.2 1.2 1 0 0 1 1 1 0 Uncharacterised protein, DegV family COG1307 Ribosomal_S24e PF01282.19 KKK27206.1 - 7.5e-36 121.9 0.2 1.2e-35 121.2 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein S24e RRXRR PF14239.6 KKK27206.1 - 0.022 14.6 2.7 0.03 14.2 2.5 1.4 1 1 0 1 1 1 0 RRXRR protein Ribosomal_S3Ae PF01015.18 KKK27208.1 - 1.9e-06 27.6 0.2 4.6e-06 26.4 0.1 1.6 2 0 0 2 2 2 1 Ribosomal S3Ae family NAD_binding_6 PF08030.12 KKK27209.1 - 4.8e-07 30.0 0.0 0.00026 21.2 0.0 2.2 1 1 0 2 2 2 2 Ferric reductase NAD binding domain NAD_binding_1 PF00175.21 KKK27209.1 - 2.5e-05 24.8 0.0 0.11 13.2 0.0 2.5 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain Pantoate_ligase PF02569.15 KKK27209.1 - 0.16 11.2 0.0 0.25 10.5 0.0 1.2 1 0 0 1 1 1 0 Pantoate-beta-alanine ligase DUF5305 PF17231.2 KKK27210.1 - 0.0099 15.3 0.5 0.019 14.4 0.1 1.6 2 0 0 2 2 2 1 Family of unknown function (DUF5305) Tetraspanin PF00335.20 KKK27210.1 - 0.087 12.5 0.1 0.56 9.9 0.1 2.0 2 0 0 2 2 2 0 Tetraspanin family Shisa PF13908.6 KKK27210.1 - 0.1 12.9 1.3 0.17 12.2 0.2 2.0 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator Baculo_11_kDa PF06143.11 KKK27210.1 - 0.12 12.0 2.7 5.6 6.6 0.4 3.0 3 0 0 3 3 3 0 Baculovirus 11 kDa family SUR7 PF06687.12 KKK27210.1 - 0.19 11.4 6.9 3.7 7.1 0.1 2.2 1 1 0 2 2 2 0 SUR7/PalI family AA_permease PF00324.21 KKK27211.1 - 2.5e-82 277.0 42.5 1.5e-57 195.3 22.9 2.0 1 1 1 2 2 2 2 Amino acid permease AA_permease_2 PF13520.6 KKK27211.1 - 4.6e-20 71.8 46.5 5.1e-17 61.8 25.7 2.1 1 1 1 2 2 2 2 Amino acid permease Epimerase PF01370.21 KKK27212.1 - 3.3e-08 33.3 0.0 0.0067 15.9 0.0 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KKK27212.1 - 7.3e-06 26.0 0.1 1.3e-05 25.2 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 KKK27212.1 - 5.1e-05 22.6 0.0 8.2e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Semialdhyde_dh PF01118.24 KKK27212.1 - 0.0002 21.8 0.0 0.00047 20.6 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NmrA PF05368.13 KKK27212.1 - 0.0003 20.4 0.1 0.0005 19.7 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family DXP_reductoisom PF02670.16 KKK27212.1 - 0.015 16.0 0.0 0.03 15.1 0.0 1.6 1 1 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Polysacc_synt_2 PF02719.15 KKK27212.1 - 0.14 11.2 0.0 0.23 10.6 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Fungal_trans_2 PF11951.8 KKK27213.1 - 1.9e-07 30.3 0.0 4.6e-07 29.0 0.0 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain AA_permease_2 PF13520.6 KKK27214.1 - 2.1e-53 181.7 46.8 2.7e-53 181.4 46.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KKK27214.1 - 5.2e-29 101.2 40.3 7e-29 100.7 40.3 1.1 1 0 0 1 1 1 1 Amino acid permease Ribosomal_S19e PF01090.19 KKK27215.1 - 7.6e-59 197.3 0.2 8.6e-59 197.2 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e Pex2_Pex12 PF04757.14 KKK27216.1 - 3.1e-37 128.3 1.2 4.5e-37 127.8 1.2 1.2 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_4 PF15227.6 KKK27216.1 - 0.0015 18.6 4.8 0.0033 17.6 4.8 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 KKK27216.1 - 0.026 14.6 1.4 0.073 13.1 1.4 1.8 1 1 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KKK27216.1 - 0.1 12.4 1.6 0.88 9.5 0.4 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) bZIP_1 PF00170.21 KKK27217.1 - 3.9e-08 33.3 11.8 6.6e-08 32.5 9.6 2.1 1 1 1 2 2 2 2 bZIP transcription factor bZIP_2 PF07716.15 KKK27217.1 - 6e-05 23.0 12.4 0.0028 17.7 6.9 2.3 1 1 1 2 2 2 2 Basic region leucine zipper KASH_CCD PF14662.6 KKK27217.1 - 0.00035 20.5 3.0 0.00035 20.5 3.0 1.4 1 1 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH Phlebovirus_NSM PF07246.11 KKK27217.1 - 0.0006 19.3 2.3 0.0008 18.9 2.3 1.1 1 0 0 1 1 1 1 Phlebovirus nonstructural protein NS-M DUF812 PF05667.11 KKK27217.1 - 0.00087 18.3 2.2 0.001 18.1 2.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF812) YabA PF06156.13 KKK27217.1 - 0.0015 19.1 1.5 0.0015 19.1 1.5 1.8 1 1 1 2 2 2 1 Initiation control protein YabA PTRF_SDPR PF15237.6 KKK27217.1 - 0.0019 17.9 4.4 0.0026 17.4 4.4 1.2 1 0 0 1 1 1 1 PTRF/SDPR family Latrophilin PF02354.16 KKK27217.1 - 0.0052 15.9 1.7 0.0064 15.6 1.7 1.1 1 0 0 1 1 1 1 Latrophilin Cytoplasmic C-terminal region ZapB PF06005.12 KKK27217.1 - 0.017 15.6 6.6 0.017 15.6 6.6 2.0 2 1 1 3 3 3 0 Cell division protein ZapB OmpH PF03938.14 KKK27217.1 - 0.073 13.4 4.9 0.1 13.0 4.9 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Jnk-SapK_ap_N PF09744.9 KKK27217.1 - 0.081 13.1 9.7 0.14 12.4 9.7 1.4 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 PXA PF02194.15 KKK27217.1 - 0.11 12.5 1.4 0.14 12.1 1.4 1.1 1 0 0 1 1 1 0 PXA domain DUF4407 PF14362.6 KKK27217.1 - 0.16 11.3 1.5 0.18 11.1 1.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DivIC PF04977.15 KKK27217.1 - 0.22 11.3 0.1 0.22 11.3 0.1 2.3 1 1 1 2 2 2 0 Septum formation initiator Cnn_1N PF07989.11 KKK27217.1 - 0.27 11.4 7.1 2.9 8.1 7.1 2.3 1 1 0 1 1 1 0 Centrosomin N-terminal motif 1 LidA_Long_CC PF18641.1 KKK27217.1 - 0.32 11.0 8.4 2.2 8.3 4.9 2.1 2 0 0 2 2 2 0 LidA long coiled-coil domain IBN_N PF03810.19 KKK27219.1 - 2.7e-13 49.6 1.1 7.3e-13 48.2 0.1 2.4 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.12 KKK27219.1 - 0.0011 19.1 1.2 0.012 15.7 0.1 3.4 4 0 0 4 4 4 1 Exportin 1-like protein Phosphoesterase PF04185.14 KKK27220.1 - 1.1e-30 107.1 3.6 6.5e-30 104.5 3.6 1.9 1 1 0 1 1 1 1 Phosphoesterase family HIF-1a_CTAD PF08778.10 KKK27220.1 - 0.07 12.8 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 HIF-1 alpha C terminal transactivation domain ILVD_EDD PF00920.21 KKK27223.1 - 3.7e-210 698.9 0.8 4.4e-210 698.7 0.8 1.0 1 0 0 1 1 1 1 Dehydratase family Ldh_2 PF02615.14 KKK27224.1 - 1e-124 416.1 0.0 1.1e-124 415.9 0.0 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase Latrotoxin_C PF15658.6 KKK27224.1 - 0.023 14.5 0.0 0.036 13.8 0.0 1.4 1 0 0 1 1 1 0 Latrotoxin C-terminal domain Abhydrolase_1 PF00561.20 KKK27225.1 - 3.1e-15 56.5 0.1 6.1e-14 52.3 0.1 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KKK27225.1 - 5e-15 56.7 3.2 9.7e-15 55.8 2.4 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KKK27225.1 - 9.7e-11 41.4 0.0 5e-10 39.1 0.0 2.1 2 1 0 2 2 2 1 Serine aminopeptidase, S33 DSPc PF00782.20 KKK27225.1 - 8.4e-10 38.6 0.0 2.1e-09 37.3 0.0 1.6 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KKK27225.1 - 0.00054 19.6 0.0 0.0016 18.0 0.0 1.7 2 0 0 2 2 2 1 Protein-tyrosine phosphatase Ser_hydrolase PF06821.13 KKK27225.1 - 0.00097 19.0 0.0 0.0035 17.2 0.0 1.8 2 0 0 2 2 2 1 Serine hydrolase PTPlike_phytase PF14566.6 KKK27225.1 - 0.0014 18.7 0.0 0.0025 17.9 0.0 1.3 1 0 0 1 1 1 1 Inositol hexakisphosphate Thioesterase PF00975.20 KKK27225.1 - 0.002 18.3 0.1 0.0037 17.4 0.1 1.4 1 0 0 1 1 1 1 Thioesterase domain FSH1 PF03959.13 KKK27225.1 - 0.025 14.2 0.0 0.37 10.4 0.0 2.2 1 1 0 1 1 1 0 Serine hydrolase (FSH1) PGAP1 PF07819.13 KKK27225.1 - 0.12 12.1 0.0 4.2 7.0 0.0 2.3 2 0 0 2 2 2 0 PGAP1-like protein GPI-anchored PF10342.9 KKK27226.1 - 3.4e-23 82.2 0.1 3.4e-23 82.2 0.1 3.2 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family BAF1_ABF1 PF04684.13 KKK27226.1 - 2.2 7.2 8.1 2.6 7.0 8.1 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor RIFIN PF02009.16 KKK27226.1 - 7.9 6.3 11.3 11 5.8 11.3 1.3 1 0 0 1 1 1 0 Rifin Aldedh PF00171.22 KKK27227.1 - 8e-132 440.0 1.2 9.8e-132 439.7 1.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Protoglobin PF11563.8 KKK27228.1 - 2.1e-43 148.0 1.5 2e-36 125.3 0.4 2.1 1 1 1 2 2 2 2 Protoglobin Cellulase PF00150.18 KKK27229.1 - 3e-18 66.3 0.7 4e-18 65.8 0.0 1.5 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_42 PF02449.15 KKK27229.1 - 0.075 12.4 0.0 0.32 10.3 0.0 1.8 2 0 0 2 2 2 0 Beta-galactosidase Glyco_hydro_35 PF01301.19 KKK27229.1 - 0.16 11.6 0.0 0.33 10.5 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolases family 35 PH_6 PF15406.6 KKK27230.1 - 1.2e-37 128.6 1.2 1.2e-37 128.6 1.2 3.0 2 1 1 3 3 3 1 Pleckstrin homology domain PH PF00169.29 KKK27230.1 - 2.3e-08 34.5 0.0 6.1e-08 33.1 0.0 1.8 1 1 0 1 1 1 1 PH domain PH_13 PF16652.5 KKK27230.1 - 0.052 13.4 0.1 0.088 12.6 0.1 1.4 1 0 0 1 1 1 0 Pleckstrin homology domain Sulfate_transp PF00916.20 KKK27231.1 - 2.1e-28 99.2 4.0 3.5e-28 98.5 4.0 1.3 1 0 0 1 1 1 1 Sulfate permease family cNMP_binding PF00027.29 KKK27231.1 - 5.7e-16 58.4 0.0 9.8e-16 57.6 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.21 KKK27231.1 - 1.7e-09 37.3 0.1 3.3e-09 36.4 0.1 1.4 1 0 0 1 1 1 1 STAS domain Sulfate_transp PF00916.20 KKK27232.1 - 2.6e-26 92.3 17.2 3.4e-26 91.9 17.2 1.1 1 0 0 1 1 1 1 Sulfate permease family MFS_MOT1 PF16983.5 KKK27232.1 - 1.5 9.3 9.4 5.6 7.4 1.1 2.6 2 0 0 2 2 2 0 Molybdate transporter of MFS superfamily Sld5 PF05916.11 KKK27233.1 - 1.9e-13 50.8 0.0 2.9e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 GINS complex protein HMG_box PF00505.19 KKK27234.1 - 2.5e-11 43.8 1.6 2.5e-11 43.8 1.6 1.7 2 0 0 2 2 2 1 HMG (high mobility group) box MATalpha_HMGbox PF04769.12 KKK27234.1 - 0.0034 16.7 0.1 0.0056 16.0 0.1 1.2 1 0 0 1 1 1 1 Mating-type protein MAT alpha 1 HMG-box HMG_box_2 PF09011.10 KKK27234.1 - 0.0051 17.4 0.9 0.014 16.0 0.9 1.7 1 0 0 1 1 1 1 HMG-box domain T5orf172 PF10544.9 KKK27234.1 - 0.1 13.2 0.4 0.24 11.9 0.4 1.6 1 0 0 1 1 1 0 T5orf172 domain HSP70 PF00012.20 KKK27235.1 - 1.7e-10 39.7 0.3 3.3e-09 35.5 0.1 2.0 2 0 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 KKK27235.1 - 0.11 11.3 0.0 0.38 9.5 0.0 1.7 2 0 0 2 2 2 0 MreB/Mbl protein TFIIA PF03153.13 KKK27235.1 - 5.7 6.8 9.0 8.7 6.2 9.0 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF3445 PF11927.8 KKK27236.1 - 9.6e-74 247.8 0.1 1.2e-73 247.5 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) INTS5_N PF14837.6 KKK27236.1 - 0.0097 15.5 0.0 0.018 14.7 0.0 1.3 1 0 0 1 1 1 1 Integrator complex subunit 5 N-terminus SBD_N PF07005.11 KKK27237.1 - 9.6e-42 143.2 0.2 5.9e-32 111.2 0.1 2.3 2 0 0 2 2 2 2 Sugar-binding N-terminal domain NBD_C PF17042.5 KKK27237.1 - 1.9e-28 100.1 3.4 2.3e-27 96.6 2.7 2.5 2 1 0 2 2 2 1 Nucleotide-binding C-terminal domain CDC45 PF02724.14 KKK27238.1 - 3.5e-248 825.1 1.7 6.8e-247 820.9 1.7 3.0 1 1 0 1 1 1 1 CDC45-like protein Cwf_Cwc_15 PF04889.12 KKK27238.1 - 0.00094 19.0 5.7 0.00094 19.0 5.7 2.5 2 0 0 2 2 2 2 Cwf15/Cwc15 cell cycle control protein BUD22 PF09073.10 KKK27238.1 - 0.0074 15.7 34.9 0.12 11.7 15.6 2.2 2 0 0 2 2 2 2 BUD22 RNA_pol_3_Rpc31 PF11705.8 KKK27238.1 - 0.066 13.5 26.5 0.44 10.8 12.7 3.6 3 0 0 3 3 3 0 DNA-directed RNA polymerase III subunit Rpc31 Nop14 PF04147.12 KKK27238.1 - 0.46 8.6 28.0 0.51 8.5 10.8 2.1 2 0 0 2 2 2 0 Nop14-like family RR_TM4-6 PF06459.12 KKK27238.1 - 1.4 8.6 21.1 0.026 14.3 7.2 2.2 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 FAM60A PF15396.6 KKK27238.1 - 2.8 7.9 15.9 0.054 13.5 4.1 2.2 2 0 0 2 2 2 0 Protein Family FAM60A BORG_CEP PF14957.6 KKK27238.1 - 9.9 7.3 14.1 0.52 11.5 1.4 2.5 2 0 0 2 2 2 0 Cdc42 effector Peptidase_C13 PF01650.18 KKK27239.1 - 8.8e-41 140.1 0.1 1.2e-40 139.6 0.1 1.1 1 0 0 1 1 1 1 Peptidase C13 family Mito_carr PF00153.27 KKK27240.1 - 5.4e-43 144.8 8.6 8e-16 57.7 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Flavin_Reduct PF01613.18 KKK27241.1 - 2.6e-17 63.3 0.0 3.7e-17 62.8 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain Abhydrolase_1 PF00561.20 KKK27242.1 - 5e-12 46.0 0.0 3e-11 43.4 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KKK27242.1 - 0.0027 17.0 0.0 0.017 14.4 0.0 1.9 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KKK27242.1 - 0.015 15.9 0.0 0.024 15.2 0.0 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family PAP_central PF04928.17 KKK27243.1 - 5.7e-109 362.9 0.0 7.3e-109 362.5 0.0 1.1 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 KKK27243.1 - 6.9e-60 201.6 0.0 1.1e-59 200.9 0.0 1.3 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 KKK27243.1 - 3e-12 46.7 0.0 6e-12 45.7 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain 4HBT_3 PF13622.6 KKK27245.1 - 1.1e-75 255.1 0.1 1.4e-75 254.8 0.1 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 KKK27245.1 - 6.2e-24 84.3 0.0 3.5e-12 46.3 0.0 4.1 3 1 0 3 3 3 3 Acyl-CoA thioesterase Succ_CoA_lig PF13607.6 KKK27245.1 - 0.063 13.1 0.0 0.28 11.0 0.0 2.0 2 0 0 2 2 2 0 Succinyl-CoA ligase like flavodoxin domain Sec61_beta PF03911.16 KKK27246.1 - 7.4e-18 64.3 1.0 1e-17 63.8 1.0 1.2 1 0 0 1 1 1 1 Sec61beta family SCIMP PF15050.6 KKK27247.1 - 0.046 14.2 4.3 1.1 9.8 0.0 3.2 3 0 0 3 3 3 0 SCIMP protein UPF0242 PF06785.11 KKK27247.1 - 0.19 11.8 0.1 0.19 11.8 0.1 2.1 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus Oxidored_q3 PF00499.20 KKK27247.1 - 7.6 6.3 20.5 0.32 10.7 8.3 3.1 1 1 1 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 CH PF00307.31 KKK27248.1 - 5.3e-05 23.4 0.0 0.00031 20.9 0.0 2.4 2 0 0 2 2 2 1 Calponin homology (CH) domain Vezatin PF12632.7 KKK27249.1 - 9.3e-68 228.6 0.4 2.9e-67 227.0 0.0 2.1 3 0 0 3 3 3 1 Mysoin-binding motif of peroxisomes PCNA_N PF00705.18 KKK27249.1 - 6.7e-54 181.0 2.5 1.3e-53 180.0 2.5 1.5 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.15 KKK27249.1 - 3.4e-51 172.7 0.0 6.7e-51 171.8 0.0 1.5 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, C-terminal domain Rad1 PF02144.16 KKK27249.1 - 9.2e-05 21.6 0.1 0.0015 17.6 0.0 2.1 1 1 1 2 2 2 1 Repair protein Rad1/Rec1/Rad17 Rad9 PF04139.13 KKK27249.1 - 0.00018 21.1 0.0 0.00027 20.5 0.0 1.2 1 0 0 1 1 1 1 Rad9 Hus1 PF04005.12 KKK27249.1 - 0.013 14.6 0.2 0.04 13.0 0.1 1.7 2 0 0 2 2 2 0 Hus1-like protein PLDc_N PF13396.6 KKK27249.1 - 0.13 12.2 0.2 0.32 11.0 0.2 1.6 1 0 0 1 1 1 0 Phospholipase_D-nuclease N-terminal EB1 PF03271.17 KKK27250.1 - 5.4e-18 65.0 1.9 1e-17 64.1 1.9 1.5 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.31 KKK27250.1 - 1.8e-06 28.1 1.0 9e-06 25.8 0.7 1.9 2 0 0 2 2 2 1 Calponin homology (CH) domain Herpes_UL6 PF01763.16 KKK27250.1 - 0.013 14.0 0.0 0.023 13.2 0.0 1.4 2 0 0 2 2 2 0 Herpesvirus UL6 like DUF2013 PF09431.10 KKK27251.1 - 3.4e-52 176.3 1.2 3.4e-52 176.3 1.2 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2013) APG9 PF04109.16 KKK27252.1 - 6.6e-204 678.4 16.9 2.9e-192 640.0 11.9 2.0 1 1 1 2 2 2 2 Autophagy protein Apg9 Glyco_hydro_47 PF01532.20 KKK27253.1 - 1.3e-196 654.0 0.1 1.6e-196 653.7 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 SprT-like PF10263.9 KKK27254.1 - 2.9e-40 136.7 0.1 5.7e-40 135.7 0.1 1.5 1 0 0 1 1 1 1 SprT-like family Zn_ribbon_SprT PF17283.2 KKK27254.1 - 6.9e-11 41.9 4.0 1.4e-10 40.8 4.0 1.6 1 0 0 1 1 1 1 SprT-like zinc ribbon domain TMEM119 PF15724.5 KKK27254.1 - 0.047 13.8 0.3 0.047 13.8 0.3 2.9 3 0 0 3 3 3 0 TMEM119 family Zn-ribbon_8 PF09723.10 KKK27254.1 - 0.082 13.0 0.5 0.19 11.9 0.5 1.6 1 0 0 1 1 1 0 Zinc ribbon domain ADK_lid PF05191.14 KKK27254.1 - 0.19 11.7 1.0 0.53 10.3 1.0 1.8 1 0 0 1 1 1 0 Adenylate kinase, active site lid DUF4379 PF14311.6 KKK27254.1 - 0.29 11.5 3.2 0.99 9.8 3.2 1.9 1 0 0 1 1 1 0 Probable Zinc-ribbon domain Mut7-C PF01927.16 KKK27254.1 - 0.66 10.1 2.2 22 5.1 0.4 2.5 1 1 1 2 2 2 0 Mut7-C RNAse domain Aminotran_1_2 PF00155.21 KKK27255.1 - 4.5e-39 134.6 0.0 5.6e-39 134.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Glyco_hydro_17 PF00332.18 KKK27256.1 - 1.4e-07 31.4 0.5 5.4e-07 29.5 0.1 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 17 Peripla_BP_4 PF13407.6 KKK27256.1 - 0.049 13.2 0.4 3 7.3 0.1 2.5 1 1 2 3 3 3 0 Periplasmic binding protein domain Glyco_hydro_72 PF03198.14 KKK27257.1 - 1.1e-108 363.2 10.0 1.7e-105 352.8 10.0 2.1 1 1 0 1 1 1 1 Glucanosyltransferase X8 PF07983.13 KKK27257.1 - 2.4e-22 79.4 5.7 9.8e-22 77.4 5.7 2.1 1 0 0 1 1 1 1 X8 domain Glucan_synthase PF02364.15 KKK27258.1 - 0 1393.0 0.0 0 1392.6 0.0 1.1 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 KKK27258.1 - 1.9e-22 80.0 0.1 6e-22 78.4 0.1 1.9 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 HSF_DNA-bind PF00447.17 KKK27259.1 - 9.3e-32 109.5 1.8 2.1e-31 108.4 1.8 1.6 1 0 0 1 1 1 1 HSF-type DNA-binding Response_reg PF00072.24 KKK27259.1 - 2.2e-17 63.2 0.0 5.3e-17 62.0 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain DivIC PF04977.15 KKK27259.1 - 0.32 10.8 1.8 0.72 9.7 1.8 1.5 1 0 0 1 1 1 0 Septum formation initiator SlyX PF04102.12 KKK27259.1 - 0.33 11.6 8.8 0.15 12.7 5.0 2.5 2 0 0 2 2 2 0 SlyX Redoxin PF08534.10 KKK27260.1 - 3.3e-25 88.5 0.0 4.3e-25 88.1 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 KKK27260.1 - 1.3e-06 28.3 0.0 1.8e-06 27.9 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family NIF3 PF01784.18 KKK27261.1 - 4.7e-60 203.2 0.0 5.8e-60 203.0 0.0 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) BolA PF01722.18 KKK27262.1 - 6.6e-19 68.0 0.1 2.5e-18 66.1 0.0 1.9 2 1 0 2 2 2 1 BolA-like protein W2 PF02020.18 KKK27263.1 - 4.9e-18 65.0 8.3 4.9e-18 65.0 8.3 2.8 2 1 1 3 3 3 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.24 KKK27263.1 - 1.6e-10 40.3 13.7 4.8e-05 22.9 1.3 4.0 1 1 3 4 4 4 4 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.23 KKK27263.1 - 7.6e-06 25.7 0.0 1.5e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep_2 PF14602.6 KKK27263.1 - 0.00011 21.9 13.3 0.067 13.0 0.7 4.1 1 1 3 4 4 4 3 Hexapeptide repeat of succinyl-transferase NTP_transf_3 PF12804.7 KKK27263.1 - 0.0035 17.7 0.0 0.0079 16.6 0.0 1.7 1 0 0 1 1 1 1 MobA-like NTP transferase domain DUF4954 PF16314.5 KKK27263.1 - 0.012 13.8 1.3 0.023 12.9 0.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4954) RVT_connect PF06815.13 KKK27263.1 - 0.083 13.2 0.0 0.28 11.5 0.0 1.9 1 0 0 1 1 1 0 Reverse transcriptase connection domain Keratin_assoc PF09775.9 KKK27263.1 - 0.091 12.4 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Keratinocyte-associated protein 2 Peptidase_U57 PF05582.12 KKK27263.1 - 0.092 12.0 0.7 0.18 11.0 0.7 1.4 1 0 0 1 1 1 0 YabG peptidase U57 Lipoprotein_10 PF03202.13 KKK27263.1 - 0.47 10.9 3.0 0.98 9.9 0.8 2.3 2 0 0 2 2 2 0 Putative mycoplasma lipoprotein, C-terminal region MARVEL PF01284.23 KKK27265.1 - 0.00027 21.0 6.2 0.00037 20.5 5.7 1.4 1 1 0 1 1 1 1 Membrane-associating domain PTS_EIIC PF02378.18 KKK27265.1 - 0.0047 16.0 0.2 0.0078 15.3 0.2 1.2 1 0 0 1 1 1 1 Phosphotransferase system, EIIC RasGAP PF00616.19 KKK27266.1 - 9.3e-33 113.7 0.0 5.6e-23 81.7 0.0 2.5 1 1 1 2 2 2 2 GTPase-activator protein for Ras-like GTPase C2 PF00168.30 KKK27266.1 - 8.4e-08 32.4 0.3 5.8e-07 29.8 0.1 2.5 2 1 0 2 2 2 1 C2 domain Mog1 PF04603.12 KKK27267.1 - 9.9e-30 103.7 0.0 1.2e-28 100.2 0.0 2.1 1 1 0 1 1 1 1 Ran-interacting Mog1 protein HSP9_HSP12 PF04119.12 KKK27268.1 - 6.2e-29 100.2 10.9 2.7e-28 98.1 9.9 2.0 2 0 0 2 2 2 1 Heat shock protein 9/12 YtxH PF12732.7 KKK27268.1 - 0.12 12.9 1.9 0.24 12.0 1.1 1.9 1 1 0 1 1 1 0 YtxH-like protein NYN PF01936.18 KKK27269.1 - 3.3e-05 24.4 0.0 0.00019 21.9 0.0 2.2 2 1 0 2 2 2 1 NYN domain COG6 PF06419.11 KKK27270.1 - 4.6e-210 699.0 0.3 5.3e-210 698.8 0.3 1.0 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 Tnp_DNA_bind PF14706.6 KKK27270.1 - 0.16 11.9 0.1 0.68 9.8 0.1 2.1 1 0 0 1 1 1 0 Transposase DNA-binding Laminin_II PF06009.12 KKK27271.1 - 0.014 15.4 5.7 0.77 9.8 1.6 2.5 2 0 0 2 2 2 0 Laminin Domain II DUF2730 PF10805.8 KKK27271.1 - 0.07 13.2 5.1 0.2 11.8 0.1 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF2730) XhlA PF10779.9 KKK27271.1 - 0.96 9.7 6.4 18 5.6 0.1 3.4 2 1 1 3 3 3 0 Haemolysin XhlA Occludin_ELL PF07303.13 KKK27271.1 - 1.6 9.5 6.5 6 7.7 0.4 3.1 2 2 2 4 4 4 0 Occludin homology domain Proteasome PF00227.26 KKK27273.1 - 1.8e-47 161.3 0.0 2.2e-47 161.0 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.8 KKK27273.1 - 7.4e-14 50.9 2.7 7.4e-14 50.9 2.7 1.8 2 0 0 2 2 2 1 Proteasome beta subunits C terminal NUP214 PF16755.5 KKK27274.1 - 0.0032 16.8 0.1 0.013 14.8 0.1 1.8 1 1 0 1 1 1 1 Nucleoporin or Nuclear pore complex subunit NUP214=Nup159 ANAPC4_WD40 PF12894.7 KKK27274.1 - 0.0047 17.2 0.0 0.024 14.9 0.0 2.2 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Syntaxin-6_N PF09177.11 KKK27274.1 - 0.012 16.2 0.7 0.038 14.5 0.7 1.9 1 0 0 1 1 1 0 Syntaxin 6, N-terminal Nop14 PF04147.12 KKK27274.1 - 0.51 8.5 14.3 1 7.5 14.3 1.4 1 0 0 1 1 1 0 Nop14-like family Baculo_PEP_C PF04513.12 KKK27274.1 - 0.52 10.3 1.8 1.3 9.0 1.7 1.7 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus CDC45 PF02724.14 KKK27274.1 - 0.74 8.0 6.2 1.1 7.5 6.2 1.2 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 KKK27274.1 - 2.5 7.4 12.6 4.7 6.6 12.6 1.3 1 0 0 1 1 1 0 SDA1 Pox_Ag35 PF03286.14 KKK27274.1 - 8.2 6.2 13.1 28 4.4 13.1 1.9 1 0 0 1 1 1 0 Pox virus Ag35 surface protein KH_1 PF00013.29 KKK27276.1 - 9.8e-45 150.2 4.6 1.2e-17 63.4 0.3 3.2 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 KKK27276.1 - 1.5e-11 43.9 3.3 0.01 15.6 0.2 3.2 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 KKK27276.1 - 1e-05 25.3 1.1 0.71 9.8 0.0 3.3 3 0 0 3 3 3 2 KH domain MOEP19 PF16005.5 KKK27276.1 - 0.00025 21.0 0.0 0.01 15.8 0.0 2.5 3 0 0 3 3 3 1 KH-like RNA-binding domain KH_5 PF13184.6 KKK27276.1 - 0.0014 18.7 9.4 0.19 11.9 0.2 3.3 3 0 0 3 3 3 3 NusA-like KH domain CENP-K PF11802.8 KKK27277.1 - 2.3e-05 24.1 8.2 0.035 13.7 4.6 2.9 2 1 1 3 3 3 2 Centromere-associated protein K Rop-like PF05082.13 KKK27277.1 - 0.43 10.4 4.0 1.3 8.9 0.2 3.0 3 0 0 3 3 3 0 Rop-like DUF4201 PF13870.6 KKK27277.1 - 0.86 9.3 18.4 0.39 10.4 1.4 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4201) Prominin PF05478.11 KKK27277.1 - 3.1 5.7 5.0 4.3 5.2 3.6 1.8 1 1 1 2 2 2 0 Prominin DUF2407 PF10302.9 KKK27277.1 - 4.2 8.0 0.0 4.2 8.0 0.0 3.1 4 0 0 4 4 4 0 DUF2407 ubiquitin-like domain Fib_alpha PF08702.10 KKK27277.1 - 6.1 7.0 15.7 1.2 9.3 1.9 2.5 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family CP12 PF02672.15 KKK27277.1 - 7.4 7.4 6.9 2.4 9.0 0.1 3.1 3 1 1 4 4 4 0 CP12 domain TBCC_N PF16752.5 KKK27277.1 - 8.8 6.8 15.4 1.5 9.3 0.8 3.0 3 0 0 3 3 3 0 Tubulin-specific chaperone C N-terminal domain Helicase_C PF00271.31 KKK27278.1 - 1.2e-20 73.9 0.0 2.1e-17 63.4 0.0 2.8 3 0 0 3 3 3 2 Helicase conserved C-terminal domain DEAD PF00270.29 KKK27278.1 - 4.3e-20 72.2 0.0 1e-19 71.0 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase RecQ_Zn_bind PF16124.5 KKK27278.1 - 5.1e-17 62.4 10.1 5.1e-17 62.4 10.1 2.3 2 0 0 2 2 2 1 RecQ zinc-binding HRDC PF00570.23 KKK27278.1 - 2.4e-08 33.8 0.0 6.8e-08 32.4 0.0 1.8 1 0 0 1 1 1 1 HRDC domain RQC PF09382.10 KKK27278.1 - 3.4e-08 33.3 0.0 3.5e-07 30.0 0.0 2.4 1 1 0 1 1 1 1 RQC domain ResIII PF04851.15 KKK27278.1 - 1.7e-05 24.9 0.0 0.00012 22.2 0.0 2.4 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 KKK27278.1 - 0.00032 19.5 0.0 0.00044 19.1 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF4110 PF13422.6 KKK27279.1 - 4.2e-33 113.3 2.0 4.2e-33 113.3 2.0 2.7 3 0 0 3 3 3 1 Domain of unknown function (DUF4110) Kelch_3 PF13415.6 KKK27279.1 - 2.7e-28 97.7 11.7 2.2e-08 34.2 0.1 6.9 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_4 PF13418.6 KKK27279.1 - 1.8e-26 91.9 14.2 3.2e-07 30.2 0.0 6.3 6 1 0 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.6 KKK27279.1 - 1.4e-15 56.8 4.0 8.1e-05 22.5 0.0 6.3 6 0 0 6 6 6 4 Kelch motif Kelch_6 PF13964.6 KKK27279.1 - 6e-14 51.8 6.7 0.003 17.8 0.2 5.4 6 0 0 6 6 6 3 Kelch motif Kelch_2 PF07646.15 KKK27279.1 - 1.6e-11 43.7 11.0 0.0061 16.5 0.0 5.9 6 1 0 6 6 6 3 Kelch motif Kelch_1 PF01344.25 KKK27279.1 - 2.4e-09 36.6 4.3 0.14 11.8 0.1 5.2 5 1 0 5 5 5 3 Kelch motif S-antigen PF05756.11 KKK27279.1 - 0.58 10.6 3.8 2.9 8.3 3.8 2.2 1 0 0 1 1 1 0 S-antigen protein Pyridoxal_deC PF00282.19 KKK27280.1 - 2.2e-27 95.8 0.0 4.3e-27 94.8 0.0 1.3 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.21 KKK27280.1 - 0.0006 19.2 0.0 0.00082 18.7 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Hanta_nucleocap PF00846.18 KKK27280.1 - 0.0082 14.6 0.0 0.015 13.8 0.0 1.3 1 0 0 1 1 1 1 Hantavirus nucleocapsid protein SepSecS PF05889.13 KKK27280.1 - 0.011 14.5 0.0 0.017 13.8 0.0 1.2 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS BRK PF07533.16 KKK27280.1 - 0.017 14.7 0.0 0.071 12.7 0.1 2.0 2 0 0 2 2 2 0 BRK domain Abhydrolase_1 PF00561.20 KKK27281.1 - 2.8e-14 53.4 0.0 1.3e-13 51.2 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KKK27281.1 - 4e-07 29.6 0.0 6.6e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KKK27281.1 - 0.00044 20.9 0.0 0.00073 20.2 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.20 KKK27281.1 - 0.078 12.6 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Peptidase_S9 PF00326.21 KKK27281.1 - 0.092 12.2 0.1 0.98 8.8 0.0 2.5 2 1 0 2 2 2 0 Prolyl oligopeptidase family Mon1 PF03164.14 KKK27282.1 - 3.2e-154 513.9 0.0 3.7e-154 513.7 0.0 1.0 1 0 0 1 1 1 1 Trafficking protein Mon1 zf-HIT PF04438.16 KKK27283.1 - 2.2e-09 37.0 12.2 3.6e-09 36.3 12.2 1.4 1 0 0 1 1 1 1 HIT zinc finger Phage_NinH PF06322.11 KKK27283.1 - 0.034 14.0 0.2 0.081 12.8 0.2 1.5 1 0 0 1 1 1 0 Phage NinH protein RR_TM4-6 PF06459.12 KKK27283.1 - 0.44 10.3 6.5 0.56 10.0 6.5 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Ribosomal_60s PF00428.19 KKK27283.1 - 0.6 10.7 15.5 4.2 8.0 9.3 2.4 1 1 1 2 2 2 0 60s Acidic ribosomal protein DUF3464 PF11947.8 KKK27283.1 - 0.66 9.7 2.9 1.4 8.7 2.9 1.5 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 DUF3602 PF12223.8 KKK27283.1 - 2.8 8.6 6.2 1.8 9.2 3.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3602) PBP1_TM PF14812.6 KKK27283.1 - 9.4 6.7 8.8 3.6 8.0 5.2 2.0 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Dopey_N PF04118.14 KKK27284.1 - 6e-92 308.0 0.0 2.7e-89 299.3 0.0 3.3 2 1 0 2 2 2 1 Dopey, N-terminal DUF3052 PF11253.8 KKK27284.1 - 0.059 13.3 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3052) MazG PF03819.17 KKK27284.1 - 0.16 12.1 0.0 0.44 10.7 0.0 1.7 1 0 0 1 1 1 0 MazG nucleotide pyrophosphohydrolase domain CAP_N PF01213.19 KKK27284.1 - 5.4 6.4 5.8 12 5.2 5.8 1.5 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Acetyltransf_3 PF13302.7 KKK27285.1 - 0.00076 20.2 0.0 0.0011 19.6 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KKK27285.1 - 0.0064 16.7 0.0 0.0088 16.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 KKK27285.1 - 0.064 13.4 0.0 0.09 12.9 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 KKK27285.1 - 0.18 11.8 0.0 0.34 10.9 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein KAR9 PF08580.10 KKK27286.1 - 1.3e-242 807.3 7.8 1.3e-242 807.3 7.8 1.8 2 0 0 2 2 2 1 Yeast cortical protein KAR9 Tropomyosin PF00261.20 KKK27286.1 - 0.77 9.1 4.7 0.23 10.8 0.9 1.9 2 0 0 2 2 2 0 Tropomyosin Prefoldin PF02996.17 KKK27286.1 - 1.8 8.5 4.4 35 4.3 0.2 3.9 3 1 1 4 4 4 0 Prefoldin subunit MTS PF05175.14 KKK27287.1 - 8.1e-05 22.2 0.3 0.23 11.0 0.0 2.2 1 1 1 2 2 2 2 Methyltransferase small domain Methyltransf_12 PF08242.12 KKK27287.1 - 0.0014 19.3 6.4 0.0035 18.0 4.6 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KKK27287.1 - 0.064 13.1 0.0 0.33 10.8 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_25 PF13649.6 KKK27287.1 - 0.11 13.2 0.0 0.42 11.3 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Fungal_trans PF04082.18 KKK27287.1 - 0.14 11.1 0.4 4.6 6.2 0.0 2.3 3 0 0 3 3 3 0 Fungal specific transcription factor domain Corazonin PF17308.2 KKK27287.1 - 0.17 12.2 5.1 0.28 11.6 5.1 1.3 1 0 0 1 1 1 0 Pro-corazonin Menin PF05053.13 KKK27287.1 - 0.27 9.6 2.0 0.33 9.2 2.0 1.1 1 0 0 1 1 1 0 Menin Complex1_LYR_2 PF13233.6 KKK27288.1 - 1e-18 67.9 0.0 1.3e-18 67.6 0.0 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 KKK27288.1 - 1.2e-09 38.0 0.0 2e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Acylphosphatase PF00708.18 KKK27289.1 - 5.7e-19 68.3 0.1 8.1e-19 67.8 0.1 1.2 1 0 0 1 1 1 1 Acylphosphatase MBOAT PF03062.19 KKK27290.1 - 8.3e-40 137.2 16.4 3.2e-31 108.9 5.1 2.4 2 0 0 2 2 2 2 MBOAT, membrane-bound O-acyltransferase family PufQ PF05398.11 KKK27290.1 - 0.053 13.7 4.0 0.6 10.3 0.1 2.7 2 1 0 2 2 2 0 PufQ cytochrome subunit AOX PF01786.17 KKK27292.1 - 2.5e-99 331.2 0.1 3.2e-99 330.9 0.1 1.1 1 0 0 1 1 1 1 Alternative oxidase TyrRSs_C PF16714.5 KKK27294.1 - 0.2 11.5 0.0 0.39 10.5 0.0 1.4 1 0 0 1 1 1 0 Tyrosyl-tRNA synthetase C-terminal domain Methyltransf_23 PF13489.6 KKK27296.1 - 3.1e-21 75.9 0.0 4.4e-21 75.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKK27296.1 - 3.6e-10 40.4 0.0 1e-09 39.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KKK27296.1 - 3.6e-07 30.8 0.0 1.2e-06 29.2 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KKK27296.1 - 6.3e-07 29.3 0.0 3.4e-06 26.9 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KKK27296.1 - 4.9e-06 27.1 0.0 9.3e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 KKK27296.1 - 0.027 14.2 0.0 0.04 13.7 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_4 PF02390.17 KKK27296.1 - 0.061 12.8 0.0 0.13 11.7 0.0 1.6 1 0 0 1 1 1 0 Putative methyltransferase Ubie_methyltran PF01209.18 KKK27296.1 - 0.08 12.3 0.0 0.25 10.6 0.0 1.9 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family MTS PF05175.14 KKK27296.1 - 0.16 11.5 0.0 0.28 10.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain PrmA PF06325.13 KKK27296.1 - 0.17 11.2 0.0 0.27 10.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Thiamine_BP PF01910.17 KKK27297.1 - 3.5e-27 94.2 0.1 4e-27 94.0 0.1 1.0 1 0 0 1 1 1 1 Thiamine-binding protein LSM PF01423.22 KKK27298.1 - 0.00064 19.4 0.0 0.00085 19.0 0.0 1.2 1 0 0 1 1 1 1 LSM domain SelK_SelG PF10961.8 KKK27298.1 - 0.041 14.5 9.0 0.058 14.0 9.0 1.2 1 0 0 1 1 1 0 Selenoprotein SelK_SelG DUF5549 PF17703.1 KKK27298.1 - 0.092 12.4 1.5 0.11 12.2 1.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5549) DUF1688 PF07958.11 KKK27299.1 - 8.7e-180 597.9 0.0 9.9e-180 597.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) DDT PF02791.17 KKK27299.1 - 0.15 12.4 0.1 0.46 10.8 0.0 1.8 2 0 0 2 2 2 0 DDT domain Gtr1_RagA PF04670.12 KKK27300.1 - 1.1e-93 312.9 0.3 1.3e-93 312.6 0.3 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Roc PF08477.13 KKK27300.1 - 8.2e-09 35.7 0.0 1.5e-08 34.8 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKK27300.1 - 5.3e-08 32.5 0.0 7.7e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 KKK27300.1 - 7.7e-08 32.1 0.0 1.2e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 KKK27300.1 - 2.8e-07 30.6 0.0 7.2e-07 29.3 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase G-alpha PF00503.20 KKK27300.1 - 0.0014 17.9 2.2 0.52 9.4 0.0 2.4 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1_Xtn PF16897.5 KKK27300.1 - 0.0061 16.6 0.1 0.013 15.5 0.1 1.5 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain AAA_29 PF13555.6 KKK27300.1 - 0.0076 16.0 0.4 0.045 13.5 0.2 2.2 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF815 PF05673.13 KKK27300.1 - 0.0096 15.1 0.1 0.021 14.0 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) ABC_tran PF00005.27 KKK27300.1 - 0.016 15.7 0.0 0.037 14.6 0.0 1.5 1 0 0 1 1 1 0 ABC transporter RsgA_GTPase PF03193.16 KKK27300.1 - 0.074 13.0 0.2 0.44 10.4 0.0 2.3 3 0 0 3 3 3 0 RsgA GTPase AAA_7 PF12775.7 KKK27300.1 - 0.088 12.3 0.1 0.24 10.9 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region AIG1 PF04548.16 KKK27300.1 - 0.14 11.5 0.2 0.48 9.7 0.0 2.0 2 0 0 2 2 2 0 AIG1 family RabGAP-TBC PF00566.18 KKK27301.1 - 5.2e-19 68.7 0.0 1e-18 67.8 0.0 1.5 1 1 0 1 1 1 1 Rab-GTPase-TBC domain PH_RBD PF12068.8 KKK27301.1 - 1e-08 34.8 0.0 0.00059 19.3 0.0 3.5 2 1 0 2 2 2 2 Rab-binding domain (RBD) Rieske PF00355.26 KKK27302.1 - 3.9e-15 55.6 0.0 7.2e-15 54.7 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Ring_hydroxyl_A PF00848.19 KKK27303.1 - 2e-21 76.9 2.6 1.2e-10 41.8 0.1 2.2 1 1 1 2 2 2 2 Ring hydroxylating alpha subunit (catalytic domain) Tctex-1 PF03645.13 KKK27304.1 - 2.2e-35 121.0 0.0 2.5e-35 120.8 0.0 1.1 1 0 0 1 1 1 1 Tctex-1 family DUF202 PF02656.15 KKK27305.1 - 2.4e-13 50.3 5.1 2.4e-13 50.3 5.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF5337 PF17272.2 KKK27305.1 - 1.1 9.1 11.1 0.075 12.9 5.5 2.1 2 1 0 2 2 2 0 Family of unknown function (DUF5337) DUF4131 PF13567.6 KKK27305.1 - 2.9 7.5 5.9 3.5 7.2 4.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) CCDC53 PF10152.9 KKK27306.1 - 0.53 10.7 2.7 0.4 11.1 0.3 2.0 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex WD40 PF00400.32 KKK27307.1 - 4.8e-36 122.2 17.5 1.6e-10 41.4 0.2 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKK27307.1 - 8.4e-12 45.2 0.9 0.016 15.5 0.0 4.3 2 1 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KKK27307.1 - 9.7e-07 27.8 1.2 0.069 11.8 0.1 3.5 4 0 0 4 4 4 3 Nucleoporin Nup120/160 PALB2_WD40 PF16756.5 KKK27307.1 - 1.5e-05 24.1 1.9 5.1e-05 22.3 0.1 2.6 3 0 0 3 3 3 1 Partner and localizer of BRCA2 WD40 domain Ge1_WD40 PF16529.5 KKK27307.1 - 0.00035 19.7 0.0 0.58 9.0 0.0 3.7 3 1 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Frtz PF11768.8 KKK27307.1 - 0.029 12.7 0.0 0.11 10.8 0.0 1.7 1 1 1 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz Hira PF07569.11 KKK27307.1 - 0.03 14.0 1.6 0.49 10.1 0.1 3.2 2 1 2 4 4 4 0 TUP1-like enhancer of split DUF1513 PF07433.11 KKK27307.1 - 0.12 11.4 0.9 1.9 7.5 0.0 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1513) SUR7 PF06687.12 KKK27310.1 - 2.1e-47 161.5 13.8 2.5e-47 161.2 13.8 1.1 1 0 0 1 1 1 1 SUR7/PalI family Arteri_Gl PF00951.18 KKK27310.1 - 0.023 14.5 0.9 0.023 14.5 0.9 2.3 3 0 0 3 3 3 0 Arterivirus GL envelope glycoprotein SpoIIM PF01944.17 KKK27310.1 - 0.096 12.7 11.5 0.024 14.7 7.7 1.8 2 0 0 2 2 2 0 Stage II sporulation protein M Meckelin PF09773.9 KKK27310.1 - 8.5 4.3 6.9 2.1 6.3 3.5 1.6 2 0 0 2 2 2 0 Meckelin (Transmembrane protein 67) Atg14 PF10186.9 KKK27312.1 - 6e-17 61.7 14.9 1.7e-15 56.9 0.1 2.3 2 0 0 2 2 2 2 Vacuolar sorting 38 and autophagy-related subunit 14 VPS38 PF17649.1 KKK27312.1 - 6.6e-09 35.1 2.0 0.016 14.1 0.1 3.1 3 0 0 3 3 3 3 Vacuolar protein sorting 38 APG6 PF04111.12 KKK27312.1 - 0.027 14.4 0.0 0.057 13.4 0.0 1.5 1 0 0 1 1 1 0 Apg6 BARA domain IPK PF03770.16 KKK27313.1 - 1e-60 205.0 0.0 1.7e-60 204.3 0.0 1.4 1 0 0 1 1 1 1 Inositol polyphosphate kinase Pam17 PF08566.10 KKK27313.1 - 0.068 13.0 0.1 0.14 12.0 0.1 1.4 1 0 0 1 1 1 0 Mitochondrial import protein Pam17 Peptidase_C13 PF01650.18 KKK27314.1 - 0.0036 16.9 0.0 0.0065 16.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase C13 family APOBEC_N PF08210.11 KKK27314.1 - 0.18 11.7 0.0 0.38 10.6 0.0 1.5 1 0 0 1 1 1 0 APOBEC-like N-terminal domain PLAC8 PF04749.17 KKK27315.1 - 9.5e-20 71.4 16.6 1.3e-19 71.0 16.6 1.2 1 0 0 1 1 1 1 PLAC8 family ERCC4 PF02732.15 KKK27316.1 - 2.2e-35 122.2 0.0 8.7e-35 120.2 0.0 2.1 2 0 0 2 2 2 1 ERCC4 domain Glycos_transf_1 PF00534.20 KKK27316.1 - 1.8e-31 109.0 0.4 8.4e-30 103.5 0.4 2.3 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KKK27316.1 - 6.9e-15 55.5 0.0 1.7e-06 28.1 0.0 2.8 2 0 0 2 2 2 2 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 KKK27316.1 - 1e-12 48.6 0.0 2.5e-12 47.4 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 KKK27316.1 - 4.4e-06 27.2 0.4 0.086 13.3 0.3 2.9 3 0 0 3 3 3 2 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 KKK27316.1 - 0.0085 16.5 0.0 0.028 14.8 0.0 1.9 1 0 0 1 1 1 1 Glycosyl transferases group 1 MAS20 PF02064.15 KKK27316.1 - 7.7 6.6 10.1 13 5.9 0.1 2.7 2 0 0 2 2 2 0 MAS20 protein import receptor Zn_clus PF00172.18 KKK27317.1 - 4.8e-08 33.0 8.7 4.8e-08 33.0 8.7 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MIT PF04212.18 KKK27317.1 - 0.015 15.3 0.0 0.048 13.7 0.0 1.9 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain zf-RING_14 PF17978.1 KKK27317.1 - 0.27 11.7 2.8 0.63 10.5 2.8 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Mhr1 PF12829.7 KKK27318.1 - 7e-30 103.0 0.5 1.2e-29 102.2 0.5 1.4 1 0 0 1 1 1 1 Transcriptional regulation of mitochondrial recombination DUF5480 PF17576.2 KKK27318.1 - 0.14 12.2 0.0 0.27 11.3 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5480) PTCB-BRCT PF12738.7 KKK27319.1 - 6.7e-43 144.5 2.5 4.7e-23 80.9 0.4 5.0 5 0 0 5 5 5 3 twin BRCT domain BRCT PF00533.26 KKK27319.1 - 3.6e-29 100.9 4.5 1.1e-14 54.6 0.5 4.5 4 1 0 4 4 4 3 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 KKK27319.1 - 3.8e-13 49.7 0.2 5.1e-05 23.6 0.0 4.7 5 0 0 5 5 5 4 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 KKK27319.1 - 8.4e-09 35.6 3.6 7.4e-05 23.0 0.2 3.6 4 0 0 4 4 4 2 DNA ligase 3 BRCT domain RTT107_BRCT_5 PF16770.5 KKK27319.1 - 0.012 15.5 0.1 2.4 8.1 0.1 3.5 4 0 0 4 4 4 0 Regulator of Ty1 transposition protein 107 BRCT domain BRCT_3 PF18428.1 KKK27319.1 - 0.016 15.3 1.0 2.8 8.1 0.1 3.8 3 1 1 4 4 4 0 BRCA1 C Terminus (BRCT) domain Snf7 PF03357.21 KKK27320.1 - 1.7e-34 118.9 15.6 6.7e-34 117.0 15.9 1.6 2 0 0 2 2 2 1 Snf7 Remorin_C PF03763.13 KKK27320.1 - 0.68 9.8 6.4 1.5 8.7 6.2 1.7 1 1 0 1 1 1 0 Remorin, C-terminal region YlqD PF11068.8 KKK27320.1 - 2 8.8 17.0 2.9 8.3 6.6 2.1 1 1 1 2 2 2 0 YlqD protein Dynamin_N PF00350.23 KKK27321.1 - 4.8e-17 62.5 0.0 1e-16 61.4 0.0 1.6 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 KKK27321.1 - 1.8e-10 40.9 0.0 1.4e-09 38.1 0.0 2.5 2 1 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KKK27321.1 - 4.2e-06 26.4 0.3 0.00016 21.3 0.5 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain DUF2205 PF10224.9 KKK27321.1 - 0.016 15.2 0.1 0.052 13.5 0.1 1.9 1 0 0 1 1 1 0 Short coiled-coil protein AAA_18 PF13238.6 KKK27321.1 - 0.02 15.4 0.0 0.15 12.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 KKK27321.1 - 0.069 13.2 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE IIGP PF05049.13 KKK27321.1 - 0.079 12.0 0.0 0.16 11.0 0.0 1.4 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) Pro_isomerase PF00160.21 KKK27322.1 - 4e-42 144.2 0.0 7e-42 143.4 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD YjeF_N PF03853.15 KKK27322.1 - 3.9e-39 134.3 0.1 6.5e-39 133.5 0.1 1.4 1 0 0 1 1 1 1 YjeF-related protein N-terminus FDF PF09532.10 KKK27322.1 - 1.2e-07 32.6 0.6 1.2e-07 32.6 0.6 2.3 2 0 0 2 2 2 1 FDF domain U-box PF04564.15 KKK27322.1 - 0.0055 16.9 1.5 0.021 15.0 0.0 2.7 4 0 0 4 4 4 1 U-box domain Rtf2 PF04641.12 KKK27322.1 - 0.011 15.1 0.0 0.07 12.5 0.0 2.1 1 1 0 1 1 1 0 Rtf2 RING-finger zf-NOSIP PF15906.5 KKK27322.1 - 0.015 15.4 0.0 0.034 14.3 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein PP2C PF00481.21 KKK27323.1 - 5.9e-62 209.6 0.1 3.4e-50 171.1 0.2 3.1 2 1 0 2 2 2 2 Protein phosphatase 2C PIF1 PF05970.14 KKK27324.1 - 4.7e-64 216.8 0.0 2.1e-49 168.6 0.0 2.1 1 1 1 2 2 2 2 PIF1-like helicase AAA_30 PF13604.6 KKK27324.1 - 8e-24 84.4 0.0 1.5e-23 83.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KKK27324.1 - 3e-12 47.1 0.0 6e-12 46.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KKK27324.1 - 1.1e-06 29.0 0.0 4.9e-06 26.9 0.0 2.1 2 0 0 2 2 1 1 AAA domain AAA_7 PF12775.7 KKK27324.1 - 1.9e-05 24.3 0.0 3.6e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region UvrD_C_2 PF13538.6 KKK27324.1 - 0.00013 21.7 0.1 0.00075 19.3 0.1 2.3 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_16 PF13191.6 KKK27324.1 - 0.00014 22.3 0.0 0.00039 20.8 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain Herpes_Helicase PF02689.14 KKK27324.1 - 0.00033 18.7 0.1 0.0015 16.6 0.0 1.9 2 0 0 2 2 2 1 Helicase T2SSE PF00437.20 KKK27324.1 - 0.0015 17.7 0.0 0.0029 16.7 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein DUF2075 PF09848.9 KKK27324.1 - 0.002 17.4 0.2 0.037 13.3 0.0 2.5 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) RNA_helicase PF00910.22 KKK27324.1 - 0.0054 17.1 0.0 0.017 15.5 0.0 1.9 1 0 0 1 1 1 1 RNA helicase NB-ARC PF00931.22 KKK27324.1 - 0.0056 15.9 0.0 0.0094 15.2 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA PF00004.29 KKK27324.1 - 0.0073 16.7 0.0 0.017 15.6 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) UvrD-helicase PF00580.21 KKK27324.1 - 0.012 15.1 0.6 0.019 14.5 0.0 1.6 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain ATPase_2 PF01637.18 KKK27324.1 - 0.012 15.5 0.2 0.04 13.8 0.2 1.9 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_11 PF13086.6 KKK27324.1 - 0.013 15.3 2.8 0.016 15.0 0.0 2.5 3 0 0 3 3 3 0 AAA domain RsgA_GTPase PF03193.16 KKK27324.1 - 0.019 14.9 0.1 0.037 13.9 0.1 1.4 1 0 0 1 1 1 0 RsgA GTPase SH3_13 PF18335.1 KKK27324.1 - 0.02 14.7 0.0 0.059 13.2 0.0 1.7 1 0 0 1 1 1 0 ATP-dependent RecD-like DNA helicase SH3 domain Viral_helicase1 PF01443.18 KKK27324.1 - 0.024 14.4 0.1 12 5.5 0.1 2.9 2 1 0 2 2 2 0 Viral (Superfamily 1) RNA helicase PhoH PF02562.16 KKK27324.1 - 0.027 13.9 0.0 0.074 12.5 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein ResIII PF04851.15 KKK27324.1 - 0.027 14.5 0.0 0.066 13.2 0.0 1.8 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit NACHT PF05729.12 KKK27324.1 - 0.027 14.4 0.0 0.073 13.0 0.0 1.7 2 0 0 2 2 1 0 NACHT domain TrwB_AAD_bind PF10412.9 KKK27324.1 - 0.031 13.2 0.0 0.057 12.3 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain DUF5605 PF18310.1 KKK27324.1 - 0.055 13.4 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5605) AAA_14 PF13173.6 KKK27324.1 - 0.058 13.4 0.0 0.28 11.2 0.0 2.2 1 1 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 KKK27324.1 - 0.078 12.7 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain MMR_HSR1 PF01926.23 KKK27324.1 - 0.12 12.5 0.0 0.25 11.4 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_5 PF07728.14 KKK27324.1 - 0.13 12.2 0.3 1.6 8.7 0.3 2.4 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA PF00004.29 KKK27325.1 - 5.6e-10 39.8 0.2 4.5e-06 27.1 0.0 2.5 1 1 1 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KKK27325.1 - 2.9e-07 31.0 0.0 4.6e-07 30.4 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 KKK27325.1 - 0.0018 18.3 0.1 0.011 15.7 0.0 2.2 2 1 1 3 3 3 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 KKK27325.1 - 0.002 17.4 0.0 0.0028 16.9 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain NACHT PF05729.12 KKK27325.1 - 0.0042 17.0 0.0 0.01 15.8 0.0 1.7 2 0 0 2 2 2 1 NACHT domain AAA_11 PF13086.6 KKK27325.1 - 0.0046 16.8 0.0 0.0093 15.8 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KKK27325.1 - 0.0052 17.1 0.1 0.021 15.1 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KKK27325.1 - 0.0076 16.5 0.0 0.012 15.9 0.0 1.5 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 KKK27325.1 - 0.008 15.9 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 KKK27325.1 - 0.026 14.9 0.0 0.057 13.8 0.0 1.6 1 0 0 1 1 1 0 RNA helicase TsaE PF02367.17 KKK27325.1 - 0.029 14.3 0.0 0.16 12.0 0.0 1.9 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 KKK27325.1 - 0.03 13.9 0.0 0.05 13.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region NTPase_1 PF03266.15 KKK27325.1 - 0.1 12.5 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 NTPase AAA_30 PF13604.6 KKK27325.1 - 0.1 12.3 0.0 0.22 11.3 0.0 1.6 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 KKK27325.1 - 0.1 11.7 0.0 0.12 11.6 0.0 1.4 1 1 0 1 1 1 0 NB-ARC domain T2SSE PF00437.20 KKK27325.1 - 0.11 11.5 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_33 PF13671.6 KKK27325.1 - 0.12 12.5 0.0 0.29 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KKK27325.1 - 0.12 12.9 0.0 0.5 10.9 0.0 2.0 1 1 0 1 1 1 0 AAA domain FHA PF00498.26 KKK27326.1 - 2.6e-13 50.1 0.0 4.6e-13 49.3 0.0 1.5 1 0 0 1 1 1 1 FHA domain zf-RING_11 PF17123.5 KKK27326.1 - 4.4e-10 39.1 3.6 9.5e-10 38.1 3.6 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 KKK27326.1 - 3e-06 27.5 8.5 3e-06 27.5 8.5 2.0 2 0 0 2 2 2 1 Ring finger domain Yop-YscD_cpl PF16697.5 KKK27326.1 - 0.0002 21.6 0.0 0.00041 20.6 0.0 1.4 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain zf-RING_5 PF14634.6 KKK27326.1 - 0.001 19.0 6.3 0.0024 17.8 6.3 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING-like PF08746.11 KKK27326.1 - 0.017 15.4 5.4 0.049 14.0 5.4 1.8 1 0 0 1 1 1 0 RING-like domain zf-ANAPC11 PF12861.7 KKK27326.1 - 0.053 13.6 2.8 0.12 12.4 2.8 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 KKK27326.1 - 0.09 12.7 7.6 0.23 11.3 7.6 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PHD PF00628.29 KKK27326.1 - 0.17 11.8 5.8 0.38 10.7 5.8 1.6 1 0 0 1 1 1 0 PHD-finger zf-H2C2_2 PF13465.6 KKK27326.1 - 0.27 11.7 2.1 0.83 10.2 0.7 2.7 2 0 0 2 2 2 0 Zinc-finger double domain zf-rbx1 PF12678.7 KKK27326.1 - 0.39 11.0 8.7 1.3 9.3 8.7 1.9 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 KKK27326.1 - 4.3 7.6 7.3 9.2 6.5 6.6 2.0 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Arm PF00514.23 KKK27327.1 - 4.8e-74 242.4 30.7 6.8e-13 48.2 0.2 11.4 11 1 0 11 11 11 9 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 KKK27327.1 - 1.4e-18 66.9 16.4 8e-06 26.2 0.5 8.2 7 1 2 9 9 8 5 HEAT-like repeat HEAT_2 PF13646.6 KKK27327.1 - 2.6e-17 63.0 8.9 0.0023 18.3 0.1 6.9 4 2 1 6 6 6 5 HEAT repeats HEAT PF02985.22 KKK27327.1 - 2.2e-15 55.4 14.4 0.34 11.3 0.0 9.2 10 0 0 10 10 9 4 HEAT repeat Arm_2 PF04826.13 KKK27327.1 - 2e-12 47.1 5.5 3.2e-07 30.1 2.1 2.4 1 1 1 2 2 2 2 Armadillo-like Adaptin_N PF01602.20 KKK27327.1 - 8.4e-11 41.1 8.0 5.8e-07 28.4 0.7 2.7 1 1 1 2 2 2 2 Adaptin N terminal region KAP PF05804.12 KKK27327.1 - 9.8e-11 40.5 0.5 2.1e-10 39.4 0.3 1.5 1 1 0 1 1 1 1 Kinesin-associated protein (KAP) V-ATPase_H_N PF03224.14 KKK27327.1 - 6.6e-09 35.5 2.7 8.9e-05 21.9 1.5 2.8 2 1 1 3 3 3 2 V-ATPase subunit H Cnd1 PF12717.7 KKK27327.1 - 5.2e-05 23.4 7.2 0.024 14.7 0.4 4.9 2 1 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 DUF3361 PF11841.8 KKK27327.1 - 5.6e-05 23.1 6.7 1.4 8.9 0.0 4.1 2 1 2 5 5 5 3 Domain of unknown function (DUF3361) V-ATPase_H_C PF11698.8 KKK27327.1 - 0.00039 20.5 2.8 9.2 6.4 0.2 4.9 2 1 6 8 8 8 0 V-ATPase subunit H DUF5578 PF17741.1 KKK27327.1 - 0.00083 18.9 6.3 2.9 7.3 0.0 5.0 2 1 3 6 6 6 1 Family of unknown function (DUF5578) Atx10homo_assoc PF09759.9 KKK27327.1 - 0.0035 17.3 4.0 1.3 9.0 0.0 4.7 4 2 2 6 6 6 1 Spinocerebellar ataxia type 10 protein domain IFRD PF05004.13 KKK27327.1 - 0.0054 15.9 8.3 0.84 8.7 0.4 4.4 3 2 1 4 4 4 2 Interferon-related developmental regulator (IFRD) UNC45-central PF11701.8 KKK27327.1 - 0.019 14.9 2.0 1.8 8.5 0.2 3.2 2 1 0 3 3 3 0 Myosin-binding striated muscle assembly central Vac14_Fab1_bd PF12755.7 KKK27327.1 - 0.02 15.5 0.2 1.9 9.1 0.1 3.4 1 1 2 3 3 3 0 Vacuolar 14 Fab1-binding region HEAT_PBS PF03130.16 KKK27327.1 - 0.034 14.8 9.3 14 6.7 0.5 6.6 6 0 0 6 6 6 0 PBS lyase HEAT-like repeat RTP1_C1 PF10363.9 KKK27327.1 - 0.048 13.8 2.6 75 3.6 0.0 4.5 3 1 1 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 ANAPC15 PF15243.6 KKK27327.1 - 0.078 13.4 0.2 0.16 12.3 0.2 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 DAP_B PF07930.12 KKK27327.1 - 0.17 11.9 0.0 0.3 11.0 0.0 1.3 1 0 0 1 1 1 0 D-aminopeptidase, domain B Alb1 PF09135.11 KKK27328.1 - 3.8e-31 108.1 15.4 5.4e-31 107.6 15.4 1.2 1 0 0 1 1 1 1 Alb1 DUF4201 PF13870.6 KKK27328.1 - 0.012 15.3 1.5 0.015 15.0 1.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) F-protein PF00469.20 KKK27328.1 - 0.44 10.1 2.9 0.56 9.8 2.9 1.1 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef Vps16_N PF04841.13 KKK27329.1 - 8.9e-97 324.4 0.0 1.2e-96 324.0 0.0 1.1 1 0 0 1 1 1 1 Vps16, N-terminal region Vps16_C PF04840.12 KKK27329.1 - 4.2e-87 292.2 0.0 1.1e-86 290.9 0.0 1.7 2 0 0 2 2 2 1 Vps16, C-terminal region AAA_26 PF13500.6 KKK27329.1 - 0.0048 16.7 0.0 0.01 15.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain ANAPC4_WD40 PF12894.7 KKK27329.1 - 0.013 15.7 0.0 7.6 6.9 0.0 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain TruB_C PF09142.11 KKK27329.1 - 0.073 12.9 0.0 1.9 8.3 0.0 2.4 2 0 0 2 2 2 0 tRNA Pseudouridine synthase II, C terminal AAA_lid_2 PF17863.1 KKK27330.1 - 2.6e-09 36.8 0.4 2.6e-09 36.8 0.4 1.9 2 0 0 2 2 2 1 AAA lid domain Bestrophin PF01062.21 KKK27331.1 - 4.3e-55 187.2 0.0 5.5e-55 186.8 0.0 1.1 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel PUL PF08324.11 KKK27332.1 - 1e-58 198.8 0.1 1.4e-58 198.3 0.1 1.2 1 0 0 1 1 1 1 PUL domain Peptidase_C97 PF05903.14 KKK27332.1 - 3.5e-41 140.5 0.0 5.8e-41 139.8 0.0 1.4 1 0 0 1 1 1 1 PPPDE putative peptidase domain Thioredoxin PF00085.20 KKK27332.1 - 2e-15 56.6 0.0 3.7e-15 55.8 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin TraF PF13728.6 KKK27332.1 - 8.7e-05 22.4 0.0 0.00016 21.6 0.0 1.3 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_2 PF13098.6 KKK27332.1 - 0.0024 18.3 0.3 0.015 15.7 0.3 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_3 PF13192.6 KKK27332.1 - 0.006 16.6 0.0 0.013 15.5 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin domain AhpC-TSA PF00578.21 KKK27332.1 - 0.0077 16.1 0.0 0.014 15.3 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family OST3_OST6 PF04756.13 KKK27332.1 - 0.027 13.8 0.0 0.044 13.1 0.0 1.3 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family Redoxin PF08534.10 KKK27332.1 - 0.035 13.8 0.1 0.092 12.5 0.1 1.6 1 0 0 1 1 1 0 Redoxin DUF2847 PF11009.8 KKK27332.1 - 0.062 13.2 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2847) CxC5 PF18718.1 KKK27332.1 - 0.078 13.1 0.1 3.6 7.7 0.0 2.6 3 0 0 3 3 2 0 CxC5 like cysteine cluster associated with KDZ transposases SAP130_C PF16014.5 KKK27332.1 - 0.23 10.5 3.1 0.36 9.9 3.1 1.2 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP130 C-terminus EF-hand_9 PF14658.6 KKK27333.1 - 0.00027 21.2 0.0 0.16 12.3 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 KKK27333.1 - 0.087 13.3 0.0 1.8 9.1 0.0 2.7 2 2 0 2 2 2 0 EF-hand domain pair UCH PF00443.29 KKK27334.1 - 1.5e-33 116.4 0.6 3.2e-22 79.3 0.0 2.3 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KKK27334.1 - 2.2e-07 30.8 0.1 2.6e-06 27.3 0.1 2.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-RING_5 PF14634.6 KKK27335.1 - 0.00098 19.0 4.6 0.0016 18.4 4.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 KKK27335.1 - 0.0095 16.3 2.8 0.018 15.4 2.8 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KKK27335.1 - 0.01 15.7 0.4 0.01 15.7 0.4 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KKK27335.1 - 0.015 15.3 1.8 0.027 14.5 1.8 1.5 1 0 0 1 1 1 0 RING-type zinc-finger FYVE PF01363.21 KKK27335.1 - 0.045 13.9 3.0 0.076 13.2 3.0 1.4 1 0 0 1 1 1 0 FYVE zinc finger IBR PF01485.21 KKK27335.1 - 0.15 12.3 6.4 0.9 9.8 1.3 2.2 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain zinc_ribbon_5 PF13719.6 KKK27335.1 - 0.21 11.4 2.7 0.68 9.7 2.7 1.9 1 1 0 1 1 1 0 zinc-ribbon domain zf-UBP PF02148.19 KKK27335.1 - 0.52 10.7 3.3 0.82 10.1 3.3 1.3 1 0 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein zf-C3HC4_3 PF13920.6 KKK27335.1 - 0.69 9.8 7.7 2.5 8.0 7.7 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KKK27335.1 - 0.96 9.4 4.5 3.7 7.5 4.8 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) GTP_EFTU PF00009.27 KKK27336.1 - 5.9e-59 198.9 0.0 9.3e-59 198.2 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 KKK27336.1 - 5.2e-15 55.2 0.0 1.2e-14 54.0 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KKK27336.1 - 3.2e-08 33.8 0.0 1e-07 32.2 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 KKK27336.1 - 2.8e-07 30.5 0.0 6.4e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.18 KKK27336.1 - 0.012 15.4 0.0 0.053 13.3 0.0 2.1 2 0 0 2 2 2 0 Elongation factor G, domain IV MMR_HSR1 PF01926.23 KKK27336.1 - 0.076 13.1 0.0 0.22 11.6 0.0 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase RhoGAP-FF1 PF16512.5 KKK27336.1 - 0.35 11.6 1.8 2.3 8.9 0.0 2.8 3 0 0 3 3 3 0 p190-A and -B Rho GAPs FF domain EXOSC1 PF10447.9 KKK27337.1 - 1.3e-29 102.9 1.2 2e-29 102.4 1.2 1.3 1 0 0 1 1 1 1 Exosome component EXOSC1/CSL4 ECR1_N PF14382.6 KKK27337.1 - 1.3e-10 40.8 0.4 2.2e-10 40.1 0.4 1.4 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region DUF4604 PF15377.6 KKK27338.1 - 1e-23 84.7 16.2 1.1e-23 84.5 16.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) F-box-like PF12937.7 KKK27339.1 - 0.00013 21.8 0.3 0.00031 20.6 0.3 1.7 1 0 0 1 1 1 1 F-box-like Asp PF00026.23 KKK27340.1 - 6.8e-70 236.0 5.8 9.5e-70 235.5 5.8 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KKK27340.1 - 1.7e-09 38.2 1.5 5.4e-05 23.5 0.1 3.3 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KKK27340.1 - 1.2e-06 29.1 0.6 0.09 13.4 0.0 3.1 2 1 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 KKK27340.1 - 0.0038 17.8 0.7 2.6 8.7 0.0 3.1 2 1 0 2 2 2 2 gag-polyprotein putative aspartyl protease TAXi_C PF14541.6 KKK27340.1 - 0.0095 15.7 0.0 0.023 14.5 0.0 1.8 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal Triabin PF03973.13 KKK27340.1 - 0.039 13.8 0.1 0.11 12.4 0.1 1.7 1 1 1 2 2 2 0 Triabin PPC PF04151.15 KKK27340.1 - 1.7 9.8 10.6 4.7 8.4 2.6 3.0 2 1 0 2 2 2 0 Bacterial pre-peptidase C-terminal domain Zn_clus PF00172.18 KKK27341.1 - 5.7e-07 29.5 14.8 8.8e-07 29.0 14.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 KKK27342.1 - 5.8e-19 68.2 10.9 5.8e-19 68.2 10.9 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily Nodulin-like PF06813.13 KKK27342.1 - 3.6e-09 36.5 1.5 8.4e-09 35.3 1.5 1.6 1 0 0 1 1 1 1 Nodulin-like DUF3784 PF12650.7 KKK27342.1 - 4.4 7.6 0.0 4.4 7.6 0.0 5.3 5 1 1 6 6 6 0 Domain of unknown function (DUF3784) Spt20 PF12090.8 KKK27342.1 - 8 6.0 9.6 15 5.1 9.6 1.4 1 0 0 1 1 1 0 Spt20 family L51_S25_CI-B8 PF05047.16 KKK27343.1 - 5.2e-15 55.1 0.1 8.7e-15 54.4 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain RL10P_insert PF17777.1 KKK27344.1 - 1.2e-21 76.4 0.0 2e-21 75.7 0.0 1.4 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 KKK27344.1 - 5.6e-19 68.1 0.0 1.1e-18 67.2 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L10 U1snRNP70_N PF12220.8 KKK27345.1 - 1.6e-25 89.5 4.1 1.6e-25 89.5 4.1 1.7 2 0 0 2 2 2 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.22 KKK27345.1 - 6.5e-12 45.1 0.0 1.2e-11 44.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KKK27345.1 - 9.6e-05 22.4 0.0 0.00017 21.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif TIM PF00121.18 KKK27346.1 - 2.3e-90 302.2 0.5 2.6e-90 302.1 0.5 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase DeoRC PF00455.22 KKK27346.1 - 0.0019 18.1 0.6 0.76 9.7 0.3 3.0 1 1 2 3 3 3 2 DeoR C terminal sensor domain CutC PF03932.14 KKK27346.1 - 0.043 13.3 0.1 0.071 12.6 0.1 1.4 1 0 0 1 1 1 0 CutC family START PF01852.19 KKK27346.1 - 0.075 12.4 0.1 0.11 12.0 0.1 1.2 1 0 0 1 1 1 0 START domain MDM10 PF12519.8 KKK27347.1 - 1.9e-146 488.6 9.6 3.3e-124 415.3 8.7 2.0 1 1 1 2 2 2 2 Mitochondrial distribution and morphology protein 10 Porin_3 PF01459.22 KKK27347.1 - 0.026 14.0 0.1 1.9 7.9 0.0 3.0 3 0 0 3 3 3 0 Eukaryotic porin Acatn PF13000.7 KKK27347.1 - 0.18 10.3 0.6 0.25 9.8 0.6 1.1 1 0 0 1 1 1 0 Acetyl-coenzyme A transporter 1 Prp19 PF08606.11 KKK27348.1 - 1.5e-33 114.5 2.8 2.6e-33 113.8 2.8 1.4 1 0 0 1 1 1 1 Prp19/Pso4-like ANAPC4_WD40 PF12894.7 KKK27348.1 - 2.2e-17 63.1 0.3 3.9e-08 33.5 0.0 4.5 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KKK27348.1 - 2e-13 50.6 0.5 8.3e-05 23.3 0.0 5.4 5 0 0 5 5 5 3 WD domain, G-beta repeat Coatomer_WDAD PF04053.14 KKK27348.1 - 5.4e-09 35.6 0.2 9.8e-06 24.9 0.0 2.1 1 1 1 2 2 2 2 Coatomer WD associated region eIF2A PF08662.11 KKK27348.1 - 5e-06 26.5 0.1 0.0066 16.4 0.0 3.0 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A U-box PF04564.15 KKK27348.1 - 0.00038 20.6 0.0 0.0007 19.7 0.0 1.4 1 0 0 1 1 1 1 U-box domain WD40_like PF17005.5 KKK27348.1 - 0.00038 19.9 0.0 0.0023 17.3 0.0 2.1 1 1 1 2 2 2 2 WD40-like domain PQQ_2 PF13360.6 KKK27348.1 - 0.00047 19.8 4.2 0.0036 16.9 0.8 2.6 1 1 1 2 2 2 2 PQQ-like domain V_ATPase_I_N PF18670.1 KKK27348.1 - 0.0036 17.7 0.2 0.0093 16.3 0.2 1.6 1 0 0 1 1 1 1 V-type ATPase subunit I, N-terminal domain HPS3_N PF14761.6 KKK27348.1 - 0.029 13.9 0.0 12 5.3 0.0 2.7 1 1 2 3 3 3 0 Hermansky-Pudlak syndrome 3 PQQ PF01011.21 KKK27348.1 - 0.034 14.1 0.1 0.14 12.2 0.0 2.2 2 0 0 2 2 1 0 PQQ enzyme repeat Hira PF07569.11 KKK27348.1 - 0.037 13.8 0.0 3.7 7.2 0.0 3.0 1 1 1 3 3 3 0 TUP1-like enhancer of split Frtz PF11768.8 KKK27348.1 - 0.068 11.5 0.0 0.31 9.3 0.0 2.0 1 1 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz Ge1_WD40 PF16529.5 KKK27348.1 - 0.1 11.5 0.0 0.28 10.1 0.0 1.8 1 1 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein VWA_2 PF13519.6 KKK27348.1 - 0.12 13.0 0.1 0.26 11.9 0.1 1.5 1 0 0 1 1 1 0 von Willebrand factor type A domain PalH PF08733.10 KKK27349.1 - 2e-111 372.2 0.0 2.4e-111 371.9 0.0 1.1 1 0 0 1 1 1 1 PalH/RIM21 HsbA PF12296.8 KKK27350.1 - 2.6e-22 79.5 16.5 2.6e-22 79.5 16.5 3.7 2 1 1 3 3 3 1 Hydrophobic surface binding protein A FPP PF05911.11 KKK27350.1 - 4.5 5.3 6.7 5.5 5.0 6.7 1.2 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil PALP PF00291.25 KKK27351.1 - 4.8e-31 108.3 0.0 1.9e-18 66.9 0.0 2.0 1 1 1 2 2 2 2 Pyridoxal-phosphate dependent enzyme GRDP-like PF07173.12 KKK27352.1 - 1.1e-18 68.2 0.1 1e-13 52.2 0.0 2.5 2 0 0 2 2 2 2 Glycine-rich domain-containing protein-like Glyco_hydro_16 PF00722.21 KKK27353.1 - 4.5e-41 140.3 4.5 4.5e-41 140.3 4.5 1.5 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 ERG2_Sigma1R PF04622.12 KKK27353.1 - 0.094 12.0 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 ERG2 and Sigma1 receptor like protein DJ-1_PfpI PF01965.24 KKK27354.1 - 2.7e-07 30.5 0.0 6e-07 29.4 0.0 1.8 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 KKK27354.1 - 0.0025 17.5 0.0 0.008 15.9 0.0 1.8 1 1 0 1 1 1 1 ThiJ/PfpI family-like p450 PF00067.22 KKK27356.1 - 5.3e-55 187.0 0.1 7.5e-55 186.5 0.1 1.1 1 0 0 1 1 1 1 Cytochrome P450 CBM_1 PF00734.18 KKK27357.1 - 2.2e-10 40.3 15.0 2.2e-10 40.3 15.0 2.3 2 0 0 2 2 2 1 Fungal cellulose binding domain BNR PF02012.20 KKK27357.1 - 3.7e-07 29.2 44.0 0.23 11.6 0.1 9.8 9 0 0 9 9 9 6 BNR/Asp-box repeat BNR_6 PF15899.5 KKK27357.1 - 0.0042 17.0 15.5 7 7.0 0.1 7.3 8 0 0 8 8 8 3 BNR-Asp box repeat BNR_2 PF13088.6 KKK27357.1 - 0.041 13.2 0.3 0.041 13.2 0.3 5.6 4 2 2 6 6 6 0 BNR repeat-like domain TEX19 PF15553.6 KKK27357.1 - 0.11 12.5 0.1 0.25 11.3 0.1 1.5 1 0 0 1 1 1 0 Testis-expressed protein 19 DUF2452 PF10504.9 KKK27357.1 - 0.18 11.3 0.0 0.32 10.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2452) Sugar_tr PF00083.24 KKK27358.1 - 4.7e-129 431.2 26.7 5.4e-129 431.0 26.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKK27358.1 - 7.9e-24 84.2 72.1 6.2e-22 78.0 39.4 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Phosphoesterase PF04185.14 KKK27359.1 - 2.3e-79 267.2 1.3 2.3e-79 267.2 1.3 1.4 2 0 0 2 2 2 1 Phosphoesterase family Fascin PF06268.13 KKK27359.1 - 2.2e-05 24.6 1.8 8.4e-05 22.8 0.2 2.3 1 1 1 2 2 2 1 Fascin domain PG_isomerase_N PF18353.1 KKK27359.1 - 0.028 14.8 0.0 0.078 13.4 0.0 1.7 1 0 0 1 1 1 0 Phosphoglucose isomerase N-terminal domain Cytochrom_D1 PF02239.16 KKK27359.1 - 0.12 10.9 0.0 0.18 10.3 0.0 1.2 1 0 0 1 1 1 0 Cytochrome D1 heme domain Git3 PF11710.8 KKK27360.1 - 6.8e-25 88.0 8.7 6.8e-25 88.0 8.7 1.7 2 1 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 GPR_Gpa2_C PF11970.8 KKK27360.1 - 1.5e-08 34.6 2.2 1.8e-08 34.4 0.1 2.2 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 C-term 7tm_1 PF00001.21 KKK27360.1 - 0.0041 16.5 3.0 0.0041 16.5 3.0 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF3215 PF11503.8 KKK27360.1 - 0.013 15.4 0.1 0.026 14.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3215) Nterm_IS4 PF13006.7 KKK27360.1 - 0.1 12.8 0.1 0.3 11.3 0.1 1.7 1 0 0 1 1 1 0 Insertion element 4 transposase N-terminal Con-6 PF10346.9 KKK27361.1 - 3.3e-32 110.2 12.8 1e-13 51.0 0.2 3.7 4 0 0 4 4 4 3 Conidiation protein 6 DUF3619 PF12279.8 KKK27361.1 - 0.063 13.6 1.4 0.063 13.6 1.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3619) IncFII_repA PF02387.15 KKK27361.1 - 0.48 9.6 3.4 3.8 6.7 0.3 2.6 2 1 1 3 3 3 0 IncFII RepA protein family DUF1771 PF08590.10 KKK27361.1 - 1.2 9.6 8.5 11 6.5 0.1 3.6 3 1 0 3 3 3 0 Domain of unknown function (DUF1771) Asp PF00026.23 KKK27362.1 - 5.8e-74 249.3 12.6 6.9e-74 249.1 12.6 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KKK27362.1 - 2e-08 34.7 2.9 1.8e-06 28.3 1.9 2.8 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KKK27362.1 - 4.5e-06 27.2 1.8 0.0059 17.2 0.3 3.1 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.6 KKK27362.1 - 0.088 12.6 0.0 0.23 11.2 0.0 1.7 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal Het-C PF07217.11 KKK27363.1 - 3.1e-245 815.0 0.0 3.9e-245 814.7 0.0 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C Selenoprotein_S PF06936.11 KKK27364.1 - 0.32 10.8 10.2 0.71 9.6 10.2 1.6 1 0 0 1 1 1 0 Selenoprotein S (SelS) DUF4629 PF15442.6 KKK27364.1 - 9.7 6.4 15.0 13 6.0 13.6 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4629) Clr5 PF14420.6 KKK27365.1 - 6.4e-20 71.1 1.2 3e-19 69.0 1.2 2.3 1 0 0 1 1 1 1 Clr5 domain YozE_SAM_like PF06855.12 KKK27365.1 - 0.29 11.3 1.4 24 5.2 0.2 2.6 2 0 0 2 2 2 0 YozE SAM-like fold RNA_pol_N PF01194.17 KKK27366.1 - 7.1e-30 103.1 1.5 1.7e-29 101.9 1.5 1.7 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit XK-related PF09815.9 KKK27366.1 - 0.0082 15.2 0.0 0.014 14.4 0.0 1.3 1 0 0 1 1 1 1 XK-related protein Fer4_13 PF13370.6 KKK27366.1 - 0.18 12.3 2.3 6 7.5 0.0 3.8 2 2 2 4 4 4 0 4Fe-4S single cluster domain of Ferredoxin I WD40 PF00400.32 KKK27367.1 - 6.7e-05 23.6 12.5 0.019 15.8 0.1 7.5 8 1 0 8 8 8 1 WD domain, G-beta repeat FAD_binding_3 PF01494.19 KKK27368.1 - 4.1e-23 82.2 0.0 5.6e-22 78.4 0.0 2.1 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KKK27368.1 - 1.6e-06 27.6 0.1 0.0095 15.2 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KKK27368.1 - 4.8e-05 23.8 1.6 0.00037 21.0 0.1 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KKK27368.1 - 0.00012 22.2 0.1 0.0003 21.0 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KKK27368.1 - 0.00071 19.3 0.3 0.012 15.2 0.1 2.1 1 1 0 2 2 2 1 FAD dependent oxidoreductase SE PF08491.10 KKK27368.1 - 0.00084 18.5 0.0 0.003 16.6 0.0 1.8 2 0 0 2 2 2 1 Squalene epoxidase Amino_oxidase PF01593.24 KKK27368.1 - 0.0058 16.0 0.0 0.057 12.7 0.0 2.0 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.6 KKK27368.1 - 0.041 13.1 0.1 1.2 8.3 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KKK27368.1 - 0.13 11.0 0.3 4.5 6.0 0.1 2.2 2 0 0 2 2 2 0 Tryptophan halogenase CN_hydrolase PF00795.22 KKK27369.1 - 1.7e-35 122.6 0.0 2.8e-35 121.9 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase AAA_16 PF13191.6 KKK27370.1 - 7.3e-09 36.2 1.9 3.1e-08 34.2 0.2 2.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KKK27370.1 - 1.3e-08 35.3 0.8 1.7e-07 31.6 0.1 3.2 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KKK27370.1 - 2.9e-07 30.6 0.7 1.4e-06 28.3 0.1 2.7 2 1 0 2 2 2 1 NACHT domain TPR_12 PF13424.6 KKK27370.1 - 1.5e-06 28.3 17.9 0.49 10.7 0.2 8.5 10 0 0 10 10 8 3 Tetratricopeptide repeat TPR_10 PF13374.6 KKK27370.1 - 1.8e-05 24.4 5.4 0.049 13.5 0.0 6.0 7 0 0 7 7 5 1 Tetratricopeptide repeat AAA_7 PF12775.7 KKK27370.1 - 0.00021 20.9 0.0 0.00085 18.9 0.0 2.0 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_30 PF13604.6 KKK27370.1 - 0.0003 20.6 0.0 0.0011 18.7 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 KKK27370.1 - 0.0017 18.7 0.1 0.02 15.3 0.0 3.0 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) TPR_7 PF13176.6 KKK27370.1 - 0.0046 16.9 0.2 3.9 7.7 0.0 4.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 KKK27370.1 - 0.016 15.3 8.6 26 5.3 0.2 7.1 8 0 0 8 8 7 0 Tetratricopeptide repeat ATPase_2 PF01637.18 KKK27370.1 - 0.037 14.0 0.4 0.42 10.5 0.0 2.9 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea ABC_tran PF00005.27 KKK27370.1 - 0.045 14.3 0.5 1.8 9.1 0.0 3.5 2 0 0 2 2 2 0 ABC transporter ResIII PF04851.15 KKK27370.1 - 0.048 13.7 2.7 0.088 12.8 0.0 2.9 4 0 0 4 4 2 0 Type III restriction enzyme, res subunit IstB_IS21 PF01695.17 KKK27370.1 - 0.052 13.3 0.9 0.29 10.8 0.0 2.8 3 0 0 3 3 2 0 IstB-like ATP binding protein Mg_chelatase PF01078.21 KKK27370.1 - 0.06 12.7 0.0 0.16 11.3 0.0 1.7 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 KKK27370.1 - 0.11 12.2 1.9 0.16 11.7 0.0 2.2 3 0 0 3 3 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_11 PF13086.6 KKK27370.1 - 0.13 12.0 0.0 0.13 12.0 0.0 3.6 3 0 0 3 3 3 0 AAA domain AAA_5 PF07728.14 KKK27370.1 - 0.17 11.9 1.0 1.8 8.5 0.0 3.0 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) FadR_C PF07840.12 KKK27370.1 - 4.9 7.0 10.9 1.7 8.5 0.1 4.7 5 0 0 5 5 4 0 FadR C-terminal domain AAA_19 PF13245.6 KKK27370.1 - 5.1 7.4 10.7 0.5 10.7 0.0 3.4 3 0 0 3 3 3 0 AAA domain FAD_binding_4 PF01565.23 KKK27371.1 - 1.2e-30 106.1 5.3 2.1e-30 105.3 5.3 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KKK27371.1 - 6.9e-09 35.7 0.4 1.5e-08 34.6 0.4 1.5 1 0 0 1 1 1 1 Berberine and berberine like Aminotran_3 PF00202.21 KKK27372.1 - 3.8e-36 124.6 0.9 1.3e-31 109.6 0.9 3.0 1 1 0 1 1 1 1 Aminotransferase class-III MFS_1 PF07690.16 KKK27373.1 - 7.6e-09 34.9 15.1 9.5e-09 34.6 15.1 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF455 PF04305.14 KKK27374.1 - 8e-99 330.2 0.0 1e-98 329.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF455) Rieske PF00355.26 KKK27374.1 - 4.5e-06 26.5 0.0 1e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 KKK27374.1 - 0.0021 18.0 0.0 0.0083 16.0 0.0 2.1 2 1 0 2 2 2 1 Rieske-like [2Fe-2S] domain GST_N_3 PF13417.6 KKK27375.1 - 1.2e-05 25.6 0.0 2.8e-05 24.4 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KKK27375.1 - 0.00086 19.6 0.0 0.0031 17.8 0.0 1.9 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KKK27375.1 - 0.072 13.1 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Peptidase_A4 PF01828.17 KKK27376.1 - 3.8e-83 278.1 15.0 4.6e-83 277.8 15.0 1.1 1 0 0 1 1 1 1 Peptidase A4 family Tetraspanin PF00335.20 KKK27378.1 - 0.00032 20.5 1.7 0.00074 19.3 1.8 1.5 1 1 1 2 2 2 1 Tetraspanin family P5CR_dimer PF14748.6 KKK27379.1 - 7.1e-35 119.4 1.1 7.1e-35 119.4 1.1 1.8 2 0 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 KKK27379.1 - 1.2e-10 41.8 6.7 5.5e-05 23.7 0.2 2.7 1 1 1 2 2 2 2 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.23 KKK27379.1 - 0.0066 16.4 0.5 0.016 15.2 0.1 1.8 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.16 KKK27379.1 - 0.037 13.7 0.5 0.068 12.8 0.2 1.6 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA LANC_like PF05147.13 KKK27379.1 - 0.13 10.8 0.0 0.17 10.4 0.0 1.1 1 0 0 1 1 1 0 Lanthionine synthetase C-like protein peroxidase PF00141.23 KKK27380.1 - 1.9e-87 292.8 0.0 2.5e-45 154.9 0.0 2.1 2 0 0 2 2 2 2 Peroxidase Gemini_AL1_M PF08283.11 KKK27380.1 - 0.19 11.8 0.9 15 5.8 0.0 3.3 2 1 1 3 3 3 0 Geminivirus rep protein central domain MFS_1 PF07690.16 KKK27381.1 - 2.3e-48 164.9 16.2 2.3e-48 164.9 16.2 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KKK27381.1 - 9.3e-12 44.5 6.0 9.3e-12 44.5 6.0 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_3 PF05977.13 KKK27381.1 - 0.0062 15.0 2.8 0.011 14.1 2.8 1.4 1 0 0 1 1 1 1 Transmembrane secretion effector OATP PF03137.20 KKK27381.1 - 1 7.6 12.2 0.23 9.7 3.1 2.6 3 0 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family PH PF00169.29 KKK27384.1 - 0.15 12.6 0.0 1.8 9.1 0.0 2.3 2 1 1 3 3 3 0 PH domain Glyco_hydro_31 PF01055.26 KKK27386.1 - 5.6e-90 302.6 6.9 9.5e-90 301.9 6.9 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 GMC_oxred_N PF00732.19 KKK27387.1 - 3.2e-57 194.2 0.0 4.1e-57 193.8 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KKK27387.1 - 9e-38 130.0 0.0 1.5e-37 129.4 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.24 KKK27387.1 - 3e-06 27.1 0.6 0.0002 21.0 0.4 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KKK27387.1 - 9e-06 25.0 0.9 9.1e-05 21.7 0.3 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 KKK27387.1 - 4.9e-05 22.7 0.1 0.00012 21.4 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KKK27387.1 - 8.5e-05 22.7 0.5 0.00026 21.2 0.5 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KKK27387.1 - 0.00015 21.0 0.1 0.00024 20.3 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 KKK27387.1 - 0.00061 19.1 0.7 0.12 11.6 0.3 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KKK27387.1 - 0.00066 18.5 0.2 0.0011 17.8 0.2 1.3 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.17 KKK27387.1 - 0.0024 17.1 0.1 0.014 14.6 0.1 1.9 2 0 0 2 2 2 1 Thi4 family GIDA PF01134.22 KKK27387.1 - 0.011 14.8 0.6 0.099 11.7 0.2 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A Trp_halogenase PF04820.14 KKK27387.1 - 0.025 13.4 0.6 0.061 12.2 0.3 1.7 2 0 0 2 2 2 0 Tryptophan halogenase FAD_oxidored PF12831.7 KKK27387.1 - 0.042 13.2 0.5 0.078 12.3 0.5 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase TrkA_N PF02254.18 KKK27387.1 - 0.083 13.2 0.1 0.16 12.2 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain Catalase_C PF18011.1 KKK27387.1 - 0.15 11.7 0.0 0.93 9.1 0.0 2.0 2 0 0 2 2 2 0 C-terminal domain found in long catalases Pyr_redox PF00070.27 KKK27387.1 - 0.29 11.7 0.2 0.29 11.7 0.2 2.3 3 0 0 3 3 2 0 Pyridine nucleotide-disulphide oxidoreductase MYT1 PF08474.11 KKK27388.1 - 0.035 14.0 0.4 0.061 13.2 0.4 1.3 1 0 0 1 1 1 0 Myelin transcription factor 1 Sulfatase PF00884.23 KKK27389.1 - 2.9e-22 79.5 0.5 5.1e-22 78.7 0.5 1.3 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 KKK27389.1 - 0.00012 21.8 0.0 0.00021 21.0 0.0 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 KKK27389.1 - 0.0045 15.7 0.0 0.006 15.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Metalloenzyme PF01676.18 KKK27389.1 - 0.057 12.8 0.0 0.096 12.0 0.0 1.2 1 0 0 1 1 1 0 Metalloenzyme superfamily CDH-cyt PF16010.5 KKK27390.1 - 3.5e-66 222.4 3.3 6e-66 221.6 3.3 1.4 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase GMC_oxred_N PF00732.19 KKK27390.1 - 3.3e-28 98.9 0.0 1.6e-27 96.7 0.0 2.0 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KKK27390.1 - 4.3e-26 92.1 0.1 9.7e-26 91.0 0.1 1.6 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KKK27390.1 - 1.1e-11 44.5 0.0 4.5e-05 22.7 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KKK27390.1 - 2.4e-06 27.7 0.0 7.2e-06 26.1 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KKK27390.1 - 4.9e-06 26.0 0.0 2.7e-05 23.6 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KKK27390.1 - 0.00011 22.7 0.0 0.24 12.0 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KKK27390.1 - 0.00045 19.1 0.0 0.00089 18.1 0.0 1.4 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.7 KKK27390.1 - 0.00066 19.1 0.2 0.15 11.3 0.0 2.5 3 0 0 3 3 3 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KKK27390.1 - 0.001 18.4 0.1 0.0018 17.6 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 KKK27390.1 - 0.0029 16.7 0.1 0.0046 16.1 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 KKK27390.1 - 0.0045 16.3 0.1 0.05 12.9 0.3 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KKK27390.1 - 0.0049 16.1 0.2 0.012 14.9 0.1 1.6 2 0 0 2 2 2 1 Thi4 family TrkA_N PF02254.18 KKK27390.1 - 0.15 12.3 0.0 0.28 11.4 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain SET PF00856.28 KKK27391.1 - 0.0026 18.2 0.0 0.0064 16.9 0.0 1.6 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.18 KKK27391.1 - 0.67 10.1 8.5 1.2 9.3 8.5 1.5 1 0 0 1 1 1 0 MYND finger Methyltransf_25 PF13649.6 KKK27392.1 - 1.9e-16 60.5 0.0 3.3e-16 59.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KKK27392.1 - 3.8e-14 52.7 0.0 5.1e-14 52.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KKK27392.1 - 6.2e-12 46.0 0.0 1e-11 45.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KKK27392.1 - 2.2e-11 43.9 0.0 2.9e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KKK27392.1 - 5e-09 36.8 0.0 7.7e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KKK27392.1 - 8.4e-06 25.4 0.0 1.2e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain TehB PF03848.14 KKK27392.1 - 3.8e-05 23.2 0.0 5.8e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB FtsJ PF01728.19 KKK27392.1 - 0.00013 22.2 0.0 0.00016 21.8 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_2 PF00891.18 KKK27392.1 - 0.00016 21.0 0.0 0.00022 20.6 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain NodS PF05401.11 KKK27392.1 - 0.00087 19.0 0.0 0.0015 18.2 0.0 1.4 1 1 0 1 1 1 1 Nodulation protein S (NodS) CheR PF01739.18 KKK27392.1 - 0.00091 18.8 0.0 0.12 11.8 0.0 2.1 1 1 1 2 2 2 1 CheR methyltransferase, SAM binding domain Methyltransf_32 PF13679.6 KKK27392.1 - 0.0013 18.7 0.0 0.0022 18.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KKK27392.1 - 0.011 15.4 0.0 0.02 14.6 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.20 KKK27392.1 - 0.024 13.9 0.0 0.029 13.7 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_5 PF01795.19 KKK27392.1 - 0.099 12.1 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 MraW methylase family Methyltransf_4 PF02390.17 KKK27392.1 - 0.12 11.8 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Aspergillus_rambellii-ASM98664v1/GCA_000986645.1_ASM98664v1_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Aspergillus_rambellii-ASM98664v1/GCA_000986645.1_ASM98664v1_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Aspergillus_rambellii-ASM98664v1/GCA_000986645.1_ASM98664v1_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Aspergillus_rambellii-ASM98664v1/GCA_000986645.1_ASM98664v1_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Sun Mar 24 14:11:24 2019 # [ok]