# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- UNC-93 PF05978.11 KKK11805.1 - 0.035 13.6 6.9 0.26 10.7 0.1 2.7 2 1 0 2 2 2 0 Ion channel regulatory protein UNC-93 Ribosomal_L7Ae PF01248.21 KKK11806.1 - 1.8e-22 78.6 0.0 2.3e-22 78.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 KKK11806.1 - 0.00031 20.6 0.0 0.00031 20.6 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 PELOTA_1 PF15608.1 KKK11806.1 - 0.021 14.5 0.0 0.027 14.2 0.0 1.2 1 0 0 1 1 1 0 PELOTA RNA binding domain Abhydrolase_4 PF08386.5 KKK11807.1 - 9.7e-20 70.3 0.0 6.1e-19 67.8 0.0 2.2 2 0 0 2 2 2 1 TAP-like protein Abhydrolase_1 PF00561.15 KKK11807.1 - 5e-12 45.8 0.0 1.4e-11 44.3 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KKK11807.1 - 2e-07 31.1 0.1 2.8e-06 27.3 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family FAD_binding_3 PF01494.14 KKK11808.1 - 1.5e-20 73.6 0.0 4e-20 72.1 0.0 1.8 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 KKK11808.1 - 0.11 12.5 0.2 0.4 10.7 0.2 2.0 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Glyco_hydro_10 PF00331.15 KKK11809.1 - 2.2e-82 276.6 0.3 2.4e-82 276.5 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 zf-H2C2_2 PF13465.1 KKK11810.1 - 4.4e-09 36.1 7.2 5.5e-08 32.7 1.4 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.21 KKK11810.1 - 2.6e-08 33.7 7.6 0.0002 21.5 1.4 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type Zn_clus PF00172.13 KKK11810.1 - 1.3e-06 28.1 9.2 1.3e-06 28.1 6.4 2.4 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_4 PF13894.1 KKK11810.1 - 0.0022 18.2 17.7 0.0045 17.2 1.3 3.6 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KKK11810.1 - 0.03 14.2 12.5 0.15 11.9 0.1 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger Vps39_2 PF10367.4 KKK11810.1 - 1.3 9.2 5.6 0.75 9.9 0.2 2.8 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 Cupin_2 PF07883.6 KKK11811.1 - 1.3e-09 37.4 0.0 1.8e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.7 KKK11811.1 - 0.011 15.0 0.0 0.018 14.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Ribosomal_S4 PF00163.14 KKK11811.1 - 0.071 13.4 0.0 0.11 12.8 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein S4/S9 N-terminal domain Cupin_1 PF00190.17 KKK11811.1 - 0.072 12.5 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 Cupin Aldedh PF00171.17 KKK11812.1 - 1.7e-128 428.8 0.0 2.5e-128 428.3 0.0 1.2 1 0 0 1 1 1 1 Aldehyde dehydrogenase family adh_short PF00106.20 KKK11812.1 - 6.1e-29 101.0 0.8 1.3e-28 99.9 0.6 1.6 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KKK11812.1 - 2.5e-15 56.9 0.0 4.6e-15 56.0 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KKK11812.1 - 1.3e-11 44.5 1.3 2.2e-11 43.7 0.5 1.6 2 0 0 2 2 2 1 KR domain LuxC PF05893.9 KKK11812.1 - 1.4e-06 27.2 0.0 3.3e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) Epimerase PF01370.16 KKK11812.1 - 7.2e-05 22.3 0.0 0.00017 21.1 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1487 PF07368.6 KKK11812.1 - 0.002 17.4 0.1 0.01 15.0 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1487) Eno-Rase_NADH_b PF12242.3 KKK11812.1 - 0.045 13.5 0.7 0.17 11.6 0.5 2.1 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase AATase PF07247.7 KKK11812.1 - 0.11 11.0 0.1 4 5.8 0.0 2.2 2 0 0 2 2 2 0 Alcohol acetyltransferase MFS_1 PF07690.11 KKK11813.1 - 3e-24 85.3 35.9 7.2e-24 84.1 24.8 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KKK11813.1 - 5.6e-08 31.8 15.8 5.6e-08 31.8 11.0 3.0 2 2 1 3 3 3 2 Sugar (and other) transporter DUF4064 PF13273.1 KKK11814.1 - 0.23 11.5 5.1 0.66 10.1 1.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) Ribosomal_L5_C PF00673.16 KKK11815.1 - 7.8e-22 76.8 0.0 1.1e-21 76.3 0.0 1.2 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 KKK11815.1 - 2.8e-21 75.0 0.1 7.3e-21 73.7 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L5 LSM PF01423.17 KKK11816.1 - 1.7e-18 65.8 0.1 2.1e-18 65.6 0.0 1.1 1 0 0 1 1 1 1 LSM domain MPC PF03650.8 KKK11817.1 - 2e-35 121.2 0.0 2.3e-35 121.1 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) Phage_Coat_B PF05356.6 KKK11817.1 - 0.061 13.0 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Phage Coat protein B Aa_trans PF01490.13 KKK11818.1 - 1.2e-82 277.6 30.6 1.6e-82 277.2 21.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease PF00324.16 KKK11819.1 - 1.1e-58 198.7 33.2 1.4e-58 198.3 23.0 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KKK11819.1 - 3.4e-19 68.6 40.2 4.7e-19 68.2 27.8 1.1 1 0 0 1 1 1 1 Amino acid permease Histidinol_dh PF00815.15 KKK11820.1 - 2.6e-102 342.5 0.6 3.1e-85 286.2 0.2 2.0 1 1 0 2 2 2 2 Histidinol dehydrogenase FAD_binding_3 PF01494.14 KKK11821.1 - 3.3e-24 85.6 0.0 5.2e-24 84.9 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 KKK11821.1 - 6.8e-08 32.4 0.2 1.8e-07 31.0 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KKK11821.1 - 9.4e-08 31.3 0.2 3.1e-06 26.3 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase ADC PF06314.6 KKK11821.1 - 2.4e-07 30.3 0.0 6.6e-07 28.9 0.0 1.8 1 1 0 1 1 1 1 Acetoacetate decarboxylase (ADC) FAD_binding_2 PF00890.19 KKK11821.1 - 7.7e-06 25.0 0.5 1.2e-05 24.3 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 KKK11821.1 - 1.4e-05 25.0 0.0 2.4e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KKK11821.1 - 0.00015 22.1 0.3 0.00085 19.6 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 KKK11821.1 - 0.00025 19.8 0.5 0.0092 14.6 0.1 2.6 3 0 0 3 3 3 1 Tryptophan halogenase GIDA PF01134.17 KKK11821.1 - 0.0015 17.4 0.1 0.0023 16.8 0.1 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 KKK11821.1 - 0.0016 18.5 0.1 0.0037 17.3 0.1 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KKK11821.1 - 0.002 17.2 0.0 0.0031 16.6 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Amino_oxidase PF01593.19 KKK11821.1 - 0.0036 16.4 0.1 1.6 7.7 0.0 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase HI0933_like PF03486.9 KKK11821.1 - 0.0038 15.7 0.1 0.007 14.8 0.1 1.4 1 0 0 1 1 1 1 HI0933-like protein AlaDh_PNT_C PF01262.16 KKK11821.1 - 0.005 16.4 0.1 0.01 15.4 0.1 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.12 KKK11821.1 - 0.012 14.6 0.1 0.022 13.8 0.1 1.3 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.1 KKK11821.1 - 0.02 14.6 0.6 0.072 12.8 0.4 2.0 1 1 0 1 1 1 0 FAD-NAD(P)-binding 3HCDH_N PF02737.13 KKK11821.1 - 0.21 11.2 0.1 0.33 10.5 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lycopene_cycl PF05834.7 KKK11821.1 - 0.33 9.8 0.9 9.6 5.0 0.0 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein NDK PF00334.14 KKK11846.1 - 1.1e-18 67.3 0.0 1.3e-18 67.1 0.0 1.1 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Tfb2 PF03849.9 KKK11874.1 - 4.2e-143 476.4 0.0 8.1e-143 475.4 0.0 1.4 2 0 0 2 2 2 1 Transcription factor Tfb2 Helicase_C_3 PF13625.1 KKK11874.1 - 1.2e-05 25.0 0.0 4e-05 23.3 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SinI PF08671.5 KKK11874.1 - 0.018 14.4 0.0 0.053 12.9 0.0 1.8 1 0 0 1 1 1 0 Anti-repressor SinI NicO PF03824.11 KKK11875.1 - 1.7 7.8 5.0 2.7 7.2 3.5 1.2 1 0 0 1 1 1 0 High-affinity nickel-transport protein Zip PF02535.17 KKK11875.1 - 1.8 7.4 3.8 3.1 6.7 2.6 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter PhzC-PhzF PF02567.11 KKK11876.1 - 1.2e-14 54.1 0.1 1.8e-09 37.2 0.0 2.2 2 0 0 2 2 2 2 Phenazine biosynthesis-like protein TIMELESS PF04821.9 KKK11877.1 - 4.4e-96 321.2 0.0 9.9e-96 320.0 0.0 1.6 1 0 0 1 1 1 1 Timeless protein TIMELESS_C PF05029.8 KKK11877.1 - 5.7e-87 292.9 35.1 2.4e-64 218.2 0.0 4.2 2 1 2 4 4 4 4 Timeless protein C terminal region 3HCDH_N PF02737.13 KKK11878.1 - 4.6e-52 176.2 1.2 6.5e-52 175.8 0.9 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 KKK11878.1 - 3.9e-34 116.9 0.0 9.4e-34 115.7 0.0 1.7 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 KKK11878.1 - 0.0002 21.2 0.2 0.00046 20.0 0.1 1.6 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.11 KKK11878.1 - 0.0011 18.3 0.3 0.0034 16.8 0.1 1.8 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.18 KKK11878.1 - 0.0016 18.1 0.2 0.0029 17.3 0.1 1.5 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DAO PF01266.19 KKK11878.1 - 0.0092 14.9 0.4 0.018 13.9 0.2 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KKK11878.1 - 0.051 13.6 0.3 0.11 12.6 0.2 1.5 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 KKK11878.1 - 0.079 12.9 0.6 0.24 11.4 0.1 2.0 2 1 0 2 2 2 0 TrkA-N domain 2-Hacid_dh_C PF02826.14 KKK11878.1 - 0.092 11.8 0.2 0.2 10.8 0.1 1.7 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.12 KKK11878.1 - 0.094 13.1 1.4 0.29 11.6 0.4 2.2 1 1 1 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Actin PF00022.14 KKK11879.1 - 7.1e-109 363.8 0.0 1.1e-108 363.2 0.0 1.3 1 1 0 1 1 1 1 Actin efThoc1 PF11957.3 KKK11881.1 - 7.3e-180 598.6 5.4 9.5e-180 598.2 3.8 1.1 1 0 0 1 1 1 1 THO complex subunit 1 transcription elongation factor Homeobox PF00046.24 KKK11882.1 - 1.3e-16 59.9 3.9 2.3e-16 59.1 2.7 1.4 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KKK11882.1 - 0.024 14.3 0.2 0.088 12.5 0.1 2.0 1 0 0 1 1 1 0 Homeobox KN domain 4HBT PF03061.17 KKK11884.1 - 4e-14 52.5 0.1 5.5e-14 52.0 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.1 KKK11884.1 - 0.023 14.4 0.0 0.026 14.2 0.0 1.1 1 0 0 1 1 1 0 Thioesterase-like superfamily DUF4442 PF14539.1 KKK11884.1 - 0.031 14.2 0.0 0.045 13.7 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4442) DUF3574 PF12098.3 KKK11884.1 - 0.054 13.0 0.0 0.092 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3574) PI-PLC-X PF00388.14 KKK11884.1 - 0.15 11.4 0.0 0.21 11.0 0.0 1.3 1 1 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, X domain AAA_12 PF13087.1 KKK11885.1 - 3.9e-27 94.9 0.0 6.9e-27 94.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KKK11885.1 - 9.4e-24 84.2 0.0 2.1e-23 83.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KKK11885.1 - 4.6e-10 39.1 0.1 5e-09 35.8 0.0 2.7 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 KKK11885.1 - 1.1e-05 25.0 0.0 0.0018 17.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain ResIII PF04851.10 KKK11885.1 - 1.9e-05 24.5 0.0 4.1e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.13 KKK11885.1 - 0.00026 20.6 0.1 0.093 12.2 0.0 3.4 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_25 PF13481.1 KKK11885.1 - 0.0018 17.7 0.0 0.0045 16.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KKK11885.1 - 0.0025 17.9 0.0 0.012 15.7 0.0 2.2 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 KKK11885.1 - 0.0032 17.6 0.0 0.011 15.9 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DnaB_C PF03796.10 KKK11885.1 - 0.0036 16.2 0.1 0.27 10.0 0.0 2.8 3 0 0 3 3 3 1 DnaB-like helicase C terminal domain DEAD PF00270.24 KKK11885.1 - 0.0059 16.1 0.1 0.042 13.3 0.0 2.4 3 0 0 3 3 3 1 DEAD/DEAH box helicase AAA_16 PF13191.1 KKK11885.1 - 0.0079 16.1 0.0 0.027 14.4 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain DUF2075 PF09848.4 KKK11885.1 - 0.012 14.5 0.6 0.021 13.8 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Zeta_toxin PF06414.7 KKK11885.1 - 0.026 13.6 0.0 0.06 12.4 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin UvrD-helicase PF00580.16 KKK11885.1 - 0.028 13.7 0.0 0.089 12.0 0.0 1.9 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain AAA_17 PF13207.1 KKK11885.1 - 0.032 15.0 0.0 0.68 10.7 0.0 3.0 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.17 KKK11885.1 - 0.056 12.2 0.0 0.12 11.2 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain UvrD_C_2 PF13538.1 KKK11885.1 - 0.071 13.2 0.0 0.21 11.7 0.0 1.8 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain AAA_5 PF07728.9 KKK11885.1 - 0.072 12.8 0.0 0.2 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Arch_ATPase PF01637.13 KKK11885.1 - 0.076 12.6 0.0 0.19 11.4 0.0 1.6 1 0 0 1 1 1 0 Archaeal ATPase Parvo_NS1 PF01057.12 KKK11885.1 - 0.17 10.7 0.0 0.29 9.9 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 RNA_helicase PF00910.17 KKK11885.1 - 0.21 11.7 0.0 0.66 10.1 0.0 1.8 1 0 0 1 1 1 0 RNA helicase ATP-synt_ab PF00006.20 KKK11885.1 - 0.24 10.8 0.0 0.5 9.8 0.0 1.6 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain PIF1 PF05970.9 KKK11885.1 - 0.25 10.2 0.0 8.7 5.1 0.0 2.2 2 0 0 2 2 2 0 PIF1-like helicase RRM_1 PF00076.17 KKK11886.1 - 9.3e-16 57.2 0.0 1.3e-15 56.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KKK11886.1 - 1.8e-11 43.8 0.0 2.6e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KKK11886.1 - 1.7e-08 34.1 0.0 2.6e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RINGv PF12906.2 KKK11887.1 - 1.7e-14 53.5 9.8 3e-14 52.7 6.8 1.4 1 0 0 1 1 1 1 RING-variant domain S1FA PF04689.8 KKK11887.1 - 0.44 10.4 0.5 1.8 8.4 0.3 2.0 1 0 0 1 1 1 0 DNA binding protein S1FA DEAD PF00270.24 KKK11888.1 - 4.7e-28 97.7 0.0 3.9e-26 91.5 0.0 2.7 2 1 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KKK11888.1 - 1e-12 47.7 0.1 3.2e-12 46.1 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KKK11888.1 - 0.0024 17.7 0.0 0.01 15.6 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 KKK11888.1 - 0.011 14.5 0.0 0.22 10.2 0.0 2.2 1 1 0 1 1 1 0 SNF2 family N-terminal domain Anillin PF08174.6 KKK11889.1 - 1.5e-33 115.7 0.3 4e-33 114.4 0.2 1.7 1 0 0 1 1 1 1 Cell division protein anillin PH PF00169.24 KKK11889.1 - 9.3e-10 38.6 0.0 2.9e-09 37.0 0.0 1.8 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 KKK11889.1 - 0.047 13.9 0.0 0.12 12.6 0.0 1.8 1 0 0 1 1 1 0 Pleckstrin homology domain TFIIS_C PF01096.13 KKK11890.1 - 1.3e-14 53.5 3.0 1.3e-14 53.5 2.1 2.9 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 KKK11890.1 - 1.4e-10 40.6 1.5 1.4e-10 40.6 1.0 3.1 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit Lar_restr_allev PF14354.1 KKK11890.1 - 0.0065 16.7 2.0 0.0065 16.7 1.4 2.3 2 1 0 2 2 2 1 Restriction alleviation protein Lar GFA PF04828.9 KKK11890.1 - 0.046 13.6 10.4 0.37 10.7 0.0 2.6 1 1 2 3 3 3 0 Glutathione-dependent formaldehyde-activating enzyme zf-AD PF07776.10 KKK11890.1 - 0.17 11.9 0.2 0.17 11.9 0.1 2.8 2 1 0 3 3 3 0 Zinc-finger associated domain (zf-AD) zf-ribbon_3 PF13248.1 KKK11890.1 - 0.17 11.1 0.1 0.17 11.1 0.1 3.3 4 0 0 4 4 4 0 zinc-ribbon domain Zn_Tnp_IS1595 PF12760.2 KKK11890.1 - 0.19 11.5 12.6 0.81 9.5 3.4 2.8 2 1 0 2 2 2 0 Transposase zinc-ribbon domain Rpr2 PF04032.11 KKK11890.1 - 0.77 9.6 8.3 3.3 7.6 1.8 2.7 2 1 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain DZR PF12773.2 KKK11890.1 - 0.89 9.4 14.8 2.5 7.9 1.7 2.9 2 2 0 2 2 2 0 Double zinc ribbon C1_4 PF07975.7 KKK11890.1 - 2.2 8.3 12.3 1.6 8.7 1.1 2.7 2 1 0 2 2 2 0 TFIIH C1-like domain Nudix_N_2 PF14803.1 KKK11890.1 - 3.2 7.5 13.8 9.4 6.0 0.0 3.6 3 1 0 3 3 3 0 Nudix N-terminal zf-RING_3 PF14369.1 KKK11890.1 - 4.4 7.3 10.4 7 6.7 0.2 3.4 3 1 0 3 3 3 0 zinc-finger zf-NADH-PPase PF09297.6 KKK11890.1 - 6.8 6.2 8.6 2.7 7.5 0.1 2.9 3 0 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain SET PF00856.23 KKK11891.1 - 8.7e-10 39.1 0.0 1.9e-08 34.7 0.0 2.8 2 0 0 2 2 2 1 SET domain Rotamase PF00639.16 KKK11893.1 - 4.1e-24 85.1 0.0 5.2e-24 84.8 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.1 KKK11893.1 - 4.7e-16 59.1 0.0 5.2e-16 58.9 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.1 KKK11893.1 - 6.3e-06 26.8 0.0 7.6e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain MAM PF00629.18 KKK11893.1 - 0.01 15.6 0.0 0.012 15.4 0.0 1.2 1 0 0 1 1 1 0 MAM domain Ribosomal_L14 PF00238.14 KKK11894.1 - 7.2e-47 158.1 2.7 8e-47 157.9 1.9 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e ACPS PF01648.15 KKK11895.1 - 1e-09 38.1 0.0 3.1e-09 36.6 0.0 1.7 2 0 0 2 2 2 1 4'-phosphopantetheinyl transferase superfamily SNO PF01174.14 KKK11896.1 - 4.9e-53 179.5 0.0 5.2e-42 143.6 0.0 2.0 1 1 1 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.9 KKK11896.1 - 2.8e-08 33.4 0.0 3.7e-06 26.6 0.0 2.2 2 0 0 2 2 2 2 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.23 KKK11896.1 - 0.00075 18.9 0.0 0.0015 18.0 0.0 1.5 1 1 0 1 1 1 1 Glutamine amidotransferase class-I DJ-1_PfpI PF01965.19 KKK11896.1 - 0.003 17.0 0.0 0.0052 16.2 0.0 1.4 1 0 0 1 1 1 1 DJ-1/PfpI family DUF4066 PF13278.1 KKK11896.1 - 0.014 14.6 0.0 0.024 13.9 0.0 1.4 1 0 0 1 1 1 0 Putative amidotransferase Acyltransferase PF01553.16 KKK11897.1 - 3.4e-33 113.8 0.0 5.4e-33 113.2 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase TPR_1 PF00515.23 KKK11898.1 - 6e-38 126.9 22.5 1.7e-07 30.5 0.1 9.9 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_11 PF13414.1 KKK11898.1 - 7.9e-37 124.7 26.2 3.7e-11 42.5 0.7 8.0 5 2 4 9 9 9 8 TPR repeat TPR_2 PF07719.12 KKK11898.1 - 2.9e-35 117.3 21.9 6.3e-05 22.5 0.0 10.4 10 0 0 10 10 10 7 Tetratricopeptide repeat Apc3 PF12895.2 KKK11898.1 - 4.3e-28 97.2 16.3 2.4e-21 75.6 0.2 5.1 2 1 4 6 6 6 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 KKK11898.1 - 8e-25 86.9 20.6 1.9e-08 34.7 0.1 8.2 7 2 1 8 8 8 5 Tetratricopeptide repeat TPR_19 PF14559.1 KKK11898.1 - 4.3e-23 81.4 14.9 5.1e-06 26.7 0.6 7.5 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_8 PF13181.1 KKK11898.1 - 1.3e-22 77.7 5.6 0.0061 16.2 0.0 9.5 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_12 PF13424.1 KKK11898.1 - 1.1e-19 70.1 20.1 9e-05 22.3 0.2 7.7 5 2 2 7 7 7 6 Tetratricopeptide repeat TPR_14 PF13428.1 KKK11898.1 - 5.4e-18 63.8 10.6 0.31 11.8 0.0 9.8 6 2 2 9 9 9 5 Tetratricopeptide repeat TPR_17 PF13431.1 KKK11898.1 - 1.9e-13 49.4 16.7 0.089 13.0 0.0 8.9 10 1 1 11 11 9 5 Tetratricopeptide repeat TPR_6 PF13174.1 KKK11898.1 - 2.3e-08 33.9 11.6 0.9 10.1 0.2 8.6 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_7 PF13176.1 KKK11898.1 - 3.1e-07 29.6 10.0 0.35 10.7 0.0 7.3 7 1 0 7 7 7 1 Tetratricopeptide repeat MIT PF04212.13 KKK11898.1 - 0.0026 17.5 2.8 0.093 12.6 0.2 3.8 3 0 0 3 3 3 1 MIT (microtubule interacting and transport) domain TPR_9 PF13371.1 KKK11898.1 - 0.0088 15.8 5.0 8.8 6.2 0.2 5.7 5 1 1 6 6 6 0 Tetratricopeptide repeat Med23 PF11573.3 KKK11898.1 - 0.055 10.8 0.1 0.12 9.6 0.0 1.5 2 0 0 2 2 2 0 Mediator complex subunit 23 ChAPs PF09295.5 KKK11898.1 - 0.1 11.3 0.6 9.7 4.8 0.0 2.8 3 0 0 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_21 PF09976.4 KKK11898.1 - 0.26 11.2 5.6 5.3 6.9 0.1 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF788 PF05620.6 KKK11899.1 - 1.8e-45 154.8 0.0 2e-45 154.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF788) HeLo PF14479.1 KKK11901.1 - 0.0048 16.6 0.1 0.055 13.2 0.1 2.1 1 1 0 1 1 1 1 Prion-inhibition and propagation Pkinase_Tyr PF07714.12 KKK11901.1 - 0.077 12.0 0.0 0.31 10.0 0.0 1.8 1 1 0 1 1 1 0 Protein tyrosine kinase Peptidase_S64 PF08192.6 KKK11901.1 - 0.11 10.8 0.0 0.17 10.1 0.0 1.2 1 0 0 1 1 1 0 Peptidase family S64 DUF523 PF04463.7 KKK11901.1 - 0.14 11.9 0.0 0.81 9.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF523) DUF3395 PF11875.3 KKK11904.1 - 7e-47 158.8 0.2 7e-47 158.8 0.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3395) Nucleoplasmin PF03066.10 KKK11904.1 - 0.01 15.3 7.6 0.32 10.5 0.8 2.3 2 0 0 2 2 2 0 Nucleoplasmin RNase_H2_suC PF08615.6 KKK11904.1 - 0.076 12.8 0.4 2.8 7.8 0.0 2.3 2 0 0 2 2 2 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) eIF-3c_N PF05470.7 KKK11904.1 - 2.1 6.3 5.2 5.8 4.8 1.1 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus CDC45 PF02724.9 KKK11904.1 - 4.7 5.1 7.8 0.77 7.7 0.9 2.1 2 0 0 2 2 2 0 CDC45-like protein Septin PF00735.13 KKK11905.1 - 6.1e-39 133.7 0.1 6.1e-39 133.7 0.1 1.7 2 0 0 2 2 2 1 Septin Tox-REase-2 PF15646.1 KKK11905.1 - 0.067 13.0 0.9 0.13 12.1 0.3 1.6 1 1 0 1 1 1 0 Restriction endonuclease fold toxin 2 Myc-LZ PF02344.10 KKK11905.1 - 0.32 10.6 6.4 0.42 10.2 0.3 2.6 2 0 0 2 2 2 0 Myc leucine zipper domain Sigma_reg_C PF13791.1 KKK11905.1 - 0.75 9.8 3.5 1 9.3 1.9 1.7 1 1 1 2 2 2 0 Sigma factor regulator C-terminal APG6 PF04111.7 KKK11905.1 - 2.2 7.2 9.1 2.8 6.9 6.3 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 WD40 PF00400.27 KKK11906.1 - 4.1e-33 112.0 11.1 5.7e-06 26.0 0.2 7.5 7 0 0 7 7 7 6 WD domain, G-beta repeat PQQ PF01011.16 KKK11906.1 - 0.0014 18.0 0.1 0.019 14.4 0.0 2.5 2 0 0 2 2 2 1 PQQ enzyme repeat VID27 PF08553.5 KKK11906.1 - 0.031 12.5 0.0 0.044 12.0 0.0 1.2 1 0 0 1 1 1 0 VID27 cytoplasmic protein Kelch_6 PF13964.1 KKK11906.1 - 0.047 13.8 0.2 0.65 10.2 0.0 3.0 4 0 0 4 4 4 0 Kelch motif UPF0180 PF03698.8 KKK11906.1 - 0.16 11.8 0.0 67 3.4 0.0 3.1 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0180) ACT_7 PF13840.1 KKK11907.1 - 5.5e-23 80.2 0.3 2.8e-15 55.6 0.0 3.5 3 0 0 3 3 3 3 ACT domain SKIP_SNW PF02731.10 KKK11908.1 - 2.4e-68 228.5 4.8 2.4e-68 228.5 3.4 2.5 2 0 0 2 2 2 1 SKIP/SNW domain FAM60A PF15396.1 KKK11908.1 - 5 6.8 10.4 12 5.5 7.2 1.7 1 0 0 1 1 1 0 Protein Family FAM60A Glucosamine_iso PF01182.15 KKK11925.1 - 9.2e-24 84.2 0.0 1.6e-23 83.5 0.0 1.4 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Glyco_hydro_3 PF00933.16 KKK11926.1 - 4.6e-57 193.2 0.0 6.9e-57 192.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KKK11926.1 - 7.1e-05 22.4 0.0 0.00014 21.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Acetyltransf_1 PF00583.19 KKK11926.1 - 0.00013 21.8 0.0 0.0005 20.0 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KKK11926.1 - 0.072 13.2 0.0 0.15 12.2 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.1 KKK11926.1 - 0.073 13.0 0.2 0.53 10.2 0.1 2.5 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain NDT80_PhoG PF05224.7 KKK11927.1 - 2.2e-37 128.8 0.1 6e-37 127.4 0.1 1.8 1 1 0 1 1 1 1 NDT80 / PhoG like DNA-binding family Metallophos PF00149.23 KKK11936.1 - 5.3e-44 150.0 0.2 6.8e-44 149.6 0.2 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase LRR_4 PF12799.2 KKK11937.1 - 9.1e-15 53.8 10.8 1.4e-05 24.6 0.3 5.7 4 1 2 6 6 6 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KKK11937.1 - 1.8e-13 50.0 15.8 1.8e-07 30.7 2.1 3.9 2 1 2 4 4 4 3 Leucine rich repeat LRR_1 PF00560.28 KKK11937.1 - 1.8e-07 30.2 9.2 0.53 10.5 0.3 6.6 5 1 1 6 6 6 3 Leucine Rich Repeat LRR_6 PF13516.1 KKK11937.1 - 0.073 13.1 8.0 6.4 7.1 0.1 5.2 3 1 2 5 5 5 0 Leucine Rich repeat LRR_7 PF13504.1 KKK11937.1 - 1.2 9.5 13.9 56 4.6 0.1 6.0 6 1 0 6 6 6 0 Leucine rich repeat Fungal_trans_2 PF11951.3 KKK11938.1 - 0.00029 19.5 1.1 0.00059 18.5 0.1 1.9 2 1 0 2 2 2 1 Fungal specific transcription factor domain RdRP PF05183.7 KKK11939.1 - 1.6e-162 542.2 0.0 2e-162 541.9 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase RRM_6 PF14259.1 KKK11939.1 - 0.00046 20.0 0.0 0.0026 17.6 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DNA_binding_2 PF13724.1 KKK11939.1 - 0.016 15.3 0.0 0.036 14.2 0.0 1.6 1 0 0 1 1 1 0 DNA-binding domain RRM_1 PF00076.17 KKK11939.1 - 0.016 14.8 0.0 0.042 13.4 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TPR_11 PF13414.1 KKK11940.1 - 7.6e-25 86.3 17.4 9.9e-06 25.1 0.0 7.9 8 1 0 8 8 8 5 TPR repeat TPR_19 PF14559.1 KKK11940.1 - 9.3e-19 67.5 18.9 7.1e-07 29.4 0.0 8.5 7 2 2 9 9 9 3 Tetratricopeptide repeat TPR_17 PF13431.1 KKK11940.1 - 3.5e-14 51.7 9.6 0.019 15.1 0.0 8.1 9 0 0 9 9 7 4 Tetratricopeptide repeat TPR_16 PF13432.1 KKK11940.1 - 5.3e-14 52.4 20.2 5.1e-06 27.0 0.0 7.7 6 2 3 9 9 9 3 Tetratricopeptide repeat TPR_12 PF13424.1 KKK11940.1 - 2.1e-13 49.9 14.5 0.0039 17.0 0.6 7.7 6 1 1 7 7 7 4 Tetratricopeptide repeat TPR_2 PF07719.12 KKK11940.1 - 4.8e-13 47.9 20.3 0.0063 16.3 0.0 9.2 10 0 0 10 10 8 4 Tetratricopeptide repeat TPR_8 PF13181.1 KKK11940.1 - 1.4e-12 46.4 8.2 2.5 8.1 0.0 8.8 8 0 0 8 8 8 3 Tetratricopeptide repeat Apc3 PF12895.2 KKK11940.1 - 2.1e-12 46.9 6.4 0.0087 16.1 0.0 6.3 6 1 0 6 6 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 KKK11940.1 - 4.7e-10 38.4 15.5 1.7 8.6 0.0 8.8 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_14 PF13428.1 KKK11940.1 - 9e-10 38.3 27.9 0.0026 18.2 1.1 10.3 8 3 3 11 11 9 2 Tetratricopeptide repeat TPR_1 PF00515.23 KKK11940.1 - 1.4e-09 37.1 17.9 0.019 14.5 0.0 9.0 9 0 0 9 9 9 3 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.1 KKK11940.1 - 0.00011 22.4 0.3 0.23 11.6 0.0 2.9 2 0 0 2 2 2 2 Alkyl sulfatase dimerisation TPR_6 PF13174.1 KKK11940.1 - 0.00021 21.5 6.5 15 6.3 0.1 6.5 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_9 PF13371.1 KKK11940.1 - 0.0027 17.5 3.0 0.059 13.2 0.4 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat FXR1P_C PF12235.3 KKK11940.1 - 0.0099 15.9 9.5 0.022 14.8 6.6 1.5 1 0 0 1 1 1 1 Fragile X-related 1 protein C terminal CDC45 PF02724.9 KKK11940.1 - 0.26 9.2 3.5 0.46 8.4 2.4 1.3 1 0 0 1 1 1 0 CDC45-like protein NARP1 PF12569.3 KKK11940.1 - 0.28 9.8 7.0 5 5.7 0.1 3.4 2 2 1 3 3 3 0 NMDA receptor-regulated protein 1 TPR_20 PF14561.1 KKK11940.1 - 0.86 9.7 12.9 38 4.4 0.1 5.6 4 1 1 6 6 5 0 Tetratricopeptide repeat SAM_2 PF07647.12 KKK11941.1 - 7.4e-10 38.5 0.1 1.4e-09 37.6 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 KKK11941.1 - 9.7e-06 25.6 0.6 1.8e-05 24.8 0.1 1.7 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) DHC_N1 PF08385.7 KKK11941.1 - 0.029 12.7 3.3 0.14 10.5 0.3 2.2 1 1 1 2 2 2 0 Dynein heavy chain, N-terminal region 1 Pyr_redox PF00070.22 KKK11942.1 - 3.3e-11 43.4 0.4 7.4e-09 35.8 0.0 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KKK11942.1 - 8.9e-10 38.9 0.0 3.5e-06 27.2 0.0 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KKK11942.1 - 3.2e-08 33.7 0.1 0.018 14.9 0.0 3.2 2 2 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KKK11942.1 - 2.7e-05 23.2 2.1 0.023 13.5 0.3 3.7 4 0 0 4 4 4 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KKK11942.1 - 3e-05 23.1 0.0 0.0028 16.6 0.0 2.4 1 1 1 2 2 2 2 Lycopene cyclase protein K_oxygenase PF13434.1 KKK11942.1 - 4.8e-05 22.4 0.0 7.9e-05 21.7 0.0 1.2 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 KKK11942.1 - 0.036 13.8 0.4 21 4.8 0.1 3.5 3 1 1 4 4 4 0 FAD-NAD(P)-binding GIDA PF01134.17 KKK11942.1 - 0.061 12.1 0.5 12 4.6 0.0 3.1 3 0 0 3 3 3 0 Glucose inhibited division protein A TrkA_N PF02254.13 KKK11942.1 - 0.097 12.6 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain Mqo PF06039.10 KKK11942.1 - 0.2 9.8 0.0 0.3 9.2 0.0 1.2 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) NAD_binding_8 PF13450.1 KKK11942.1 - 0.36 10.8 1.8 16 5.6 0.1 2.5 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Fungal_trans_2 PF11951.3 KKK11943.1 - 0.39 9.2 5.5 1.9 7.0 0.1 3.0 1 1 1 3 3 3 0 Fungal specific transcription factor domain DUF3336 PF11815.3 KKK11944.1 - 4.5e-50 168.9 5.0 6.8e-50 168.3 2.7 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3336) Patatin PF01734.17 KKK11944.1 - 1.9e-20 73.7 0.3 5.3e-19 68.9 0.0 2.8 2 1 0 2 2 2 1 Patatin-like phospholipase DUF2457 PF10446.4 KKK11945.1 - 4.6e-175 582.7 36.0 4.6e-175 582.7 25.0 2.6 2 1 0 2 2 2 1 Protein of unknown function (DUF2457) Arf PF00025.16 KKK11945.1 - 9.1e-63 210.6 0.0 1.4e-62 210.0 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 KKK11945.1 - 3.1e-09 36.0 0.6 7.7e-06 24.8 0.0 2.6 1 1 0 2 2 2 2 G-protein alpha subunit Miro PF08477.8 KKK11945.1 - 2.8e-07 31.0 0.0 4e-06 27.3 0.0 2.5 2 0 0 2 2 2 1 Miro-like protein SRPRB PF09439.5 KKK11945.1 - 3.6e-07 29.5 0.0 6.7e-07 28.6 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 KKK11945.1 - 2.4e-06 27.4 0.0 4.9e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.17 KKK11945.1 - 0.00056 19.3 0.0 0.001 18.4 0.0 1.4 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 KKK11945.1 - 0.0012 18.0 0.0 0.0019 17.4 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Fungal_trans_2 PF11951.3 KKK11952.1 - 4.2e-45 153.9 0.0 6.2e-45 153.4 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK11952.1 - 0.072 13.0 3.2 0.16 11.8 2.2 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 KKK11953.1 - 1.9e-25 89.3 39.6 1.9e-25 89.3 27.4 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KKK11953.1 - 9.3e-09 34.3 30.2 2.9e-08 32.7 21.0 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 KKK11953.1 - 0.033 12.3 10.6 0.0046 15.2 3.8 1.9 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) P5CR_dimer PF14748.1 KKK11953.1 - 0.061 13.3 0.1 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Pyrroline-5-carboxylate reductase dimerisation DUF2206 PF09971.4 KKK11953.1 - 0.57 8.9 8.4 0.12 11.1 3.2 1.8 1 1 0 1 1 1 0 Predicted membrane protein (DUF2206) Fer4 PF00037.22 KKK11958.1 - 5.5e-14 51.0 16.4 3.1e-08 32.8 2.8 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.2 KKK11958.1 - 9.1e-12 45.1 10.8 1.5e-11 44.5 7.5 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.1 KKK11958.1 - 1.6e-10 41.5 7.5 5.3e-05 23.8 0.4 2.3 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_10 PF13237.1 KKK11958.1 - 2.6e-10 39.9 23.3 3e-08 33.3 8.8 1.8 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.1 KKK11958.1 - 1.3e-09 38.2 11.3 2.6e-09 37.2 7.9 1.5 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_21 PF14697.1 KKK11958.1 - 5.6e-09 35.7 32.3 1.2e-05 25.0 8.7 2.1 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_17 PF13534.1 KKK11958.1 - 7.3e-09 35.8 2.1 0.0008 19.6 0.3 2.3 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_8 PF13183.1 KKK11958.1 - 4.2e-08 33.0 21.0 2.3e-05 24.3 8.4 2.1 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_2 PF12797.2 KKK11958.1 - 1.1e-07 31.2 14.3 0.00058 19.6 1.7 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.2 KKK11958.1 - 4.5e-07 29.6 12.6 0.00057 20.0 2.1 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_6 PF12837.2 KKK11958.1 - 6.2e-07 29.0 17.4 0.0012 18.6 3.6 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_18 PF13746.1 KKK11958.1 - 0.0001 22.6 10.4 0.022 15.1 0.7 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_15 PF13459.1 KKK11958.1 - 0.004 17.6 12.6 0.23 12.0 1.1 2.8 2 1 0 2 2 2 2 4Fe-4S single cluster domain Fer4_13 PF13370.1 KKK11958.1 - 0.0091 16.3 15.7 0.3 11.5 3.2 2.7 2 1 1 3 3 3 2 4Fe-4S single cluster domain Fer4_3 PF12798.2 KKK11958.1 - 0.018 15.5 17.5 0.04 14.4 2.8 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain c-SKI_SMAD_bind PF08782.5 KKK11958.1 - 0.11 12.6 5.7 0.76 9.9 0.1 2.2 1 1 1 2 2 2 0 c-SKI Smad4 binding domain PP-binding PF00550.20 KKK11959.1 - 3.2e-10 40.1 0.2 4.7e-10 39.5 0.2 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.1 KKK11959.1 - 1.4e-06 28.2 0.1 1.8e-06 27.8 0.1 1.1 1 0 0 1 1 1 1 Acyl-carrier SURF6 PF04935.7 KKK11960.1 - 5.5e-51 172.8 24.5 5.5e-51 172.8 17.0 4.7 2 1 0 2 2 2 1 Surfeit locus protein 6 RRP14 PF15459.1 KKK11960.1 - 3.9e-23 81.3 1.0 3.9e-23 81.3 0.7 8.5 7 2 1 8 8 8 1 60S ribosome biogenesis protein Rrp14 CAF-1_p150 PF11600.3 KKK11960.1 - 0.16 11.3 100.1 0.023 14.0 7.2 4.2 4 0 0 4 4 4 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal GTP_EFTU PF00009.22 KKK11961.1 - 1.2e-34 119.4 2.2 1.2e-34 119.4 1.5 2.3 2 1 0 2 2 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 KKK11961.1 - 2.5e-24 85.2 0.0 5.4e-24 84.1 0.0 1.6 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 KKK11961.1 - 1.3e-11 44.4 3.5 5.8e-07 29.5 0.0 3.0 3 0 0 3 3 3 2 Elongation factor Tu domain 2 IF2_N PF04760.10 KKK11961.1 - 2.9e-10 39.6 0.0 9e-10 38.0 0.0 1.9 2 0 0 2 2 1 1 Translation initiation factor IF-2, N-terminal region MMR_HSR1 PF01926.18 KKK11961.1 - 4.1e-07 29.9 0.0 1.1e-06 28.6 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KKK11961.1 - 0.00054 20.4 0.1 0.0013 19.1 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KKK11961.1 - 0.0033 16.6 0.0 0.006 15.8 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 KKK11961.1 - 0.007 15.6 0.0 0.007 15.6 0.0 2.1 3 0 0 3 3 3 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 KKK11961.1 - 0.0074 15.7 0.1 0.021 14.2 0.1 1.7 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation DZR PF12773.2 KKK11961.1 - 0.013 15.2 2.1 0.025 14.3 1.4 1.4 1 0 0 1 1 1 0 Double zinc ribbon FeoB_N PF02421.13 KKK11961.1 - 0.096 11.9 0.1 0.25 10.6 0.0 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B Dynamin_N PF00350.18 KKK11961.1 - 0.15 11.9 4.6 21 4.9 0.0 4.0 3 1 1 4 4 4 0 Dynamin family MIF4G PF02854.14 KKK11961.1 - 0.43 9.9 1.0 0.8 9.0 0.7 1.4 1 0 0 1 1 1 0 MIF4G domain EI24 PF07264.6 KKK11962.1 - 3.5e-07 29.8 16.4 6.7e-07 28.9 11.4 1.4 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) Ribosomal_S2 PF00318.15 KKK11963.1 - 1.5e-51 174.5 0.0 2.1e-51 174.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S2 Mito_carr PF00153.22 KKK11964.1 - 9.8e-59 195.0 0.2 7e-19 67.3 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Antimicrobial_2 PF08023.7 KKK11964.1 - 0.12 12.6 0.5 0.38 11.1 0.3 1.8 1 0 0 1 1 1 0 Frog antimicrobial peptide BCAS2 PF05700.6 KKK11965.1 - 9.3e-58 195.2 0.7 1e-57 195.1 0.5 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) TMF_TATA_bd PF12325.3 KKK11965.1 - 0.82 9.4 7.8 2.5 7.8 5.1 2.1 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding MFS_1 PF07690.11 KKK11966.1 - 5e-40 137.3 36.2 9e-39 133.1 22.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KKK11966.1 - 3.1e-12 45.8 12.7 3.1e-12 45.8 8.8 2.1 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 KKK11966.1 - 6e-08 31.3 5.5 9.5e-08 30.6 3.8 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Zn_clus PF00172.13 KKK11967.1 - 1.4e-08 34.5 10.3 2.8e-08 33.5 7.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KKK11967.1 - 0.07 11.9 0.0 0.13 11.0 0.0 1.5 1 0 0 1 1 1 0 Fungal specific transcription factor domain Ceramidase_alk PF04734.8 KKK11968.1 - 3.4e-278 924.1 0.0 3.9e-278 923.9 0.0 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase Snf7 PF03357.16 KKK11969.1 - 1.1e-34 119.2 24.1 1.1e-34 119.2 16.7 2.0 1 1 1 2 2 2 1 Snf7 MpPF1 PF07668.6 KKK11969.1 - 0.021 14.0 3.8 0.028 13.6 2.7 1.2 1 0 0 1 1 1 0 M penetrans paralogue family 1 TraF_2 PF13729.1 KKK11969.1 - 0.15 10.8 3.2 0.08 11.7 0.5 1.7 1 1 0 1 1 1 0 F plasmid transfer operon, TraF, protein DUF3138 PF11336.3 KKK11969.1 - 0.41 8.7 7.2 0.62 8.1 5.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3138) PglZ PF08665.7 KKK11969.1 - 1.3 8.6 8.1 0.39 10.3 2.4 2.0 1 1 1 2 2 2 0 PglZ domain CRC_subunit PF08624.5 KKK11970.1 - 8e-55 184.5 0.2 1.1e-54 184.0 0.1 1.2 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit Glyco_hydro_18 PF00704.23 KKK11971.1 - 1.4e-14 54.3 5.0 3.5e-14 53.0 3.5 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 DUF4611 PF15387.1 KKK11971.1 - 0.017 15.2 1.9 0.036 14.1 1.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) PBP_sp32 PF07222.7 KKK11971.1 - 0.028 13.6 0.9 0.033 13.3 0.6 1.2 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Sporozoite_P67 PF05642.6 KKK11971.1 - 0.048 11.5 0.6 0.059 11.2 0.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF1840 PF08895.6 KKK11971.1 - 0.054 13.5 1.3 5.2 7.1 1.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) PBP1_TM PF14812.1 KKK11971.1 - 1.6 9.0 6.7 2.9 8.2 4.6 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal NMT1 PF09084.6 KKK11972.1 - 4.1e-05 23.2 0.0 0.00025 20.7 0.0 2.0 1 1 1 2 2 2 1 NMT1/THI5 like Ribosomal_L1 PF00687.16 KKK11973.1 - 6.4e-32 110.6 0.0 1.2e-31 109.7 0.0 1.5 1 1 0 1 1 1 1 Ribosomal protein L1p/L10e family tRNA-synt_1c PF00749.16 KKK11974.1 - 5.5e-101 337.3 0.0 7.8e-101 336.8 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 KKK11974.1 - 4.8e-44 150.0 0.3 1.1e-43 148.8 0.2 1.7 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C_3 PF14497.1 KKK11974.1 - 1.1e-07 32.2 0.2 3.2e-07 30.7 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KKK11974.1 - 0.017 14.9 0.0 0.043 13.7 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KKK11974.1 - 0.082 12.9 0.0 0.23 11.4 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain tRNA-synt_1e PF01406.14 KKK11974.1 - 0.1 11.7 0.3 0.25 10.4 0.1 1.6 1 1 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain E1-E2_ATPase PF00122.15 KKK11975.1 - 3.7e-76 255.1 0.2 8.6e-75 250.6 0.1 2.3 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 KKK11975.1 - 9e-26 91.6 0.0 2e-25 90.4 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KKK11975.1 - 1.5e-13 51.3 0.0 2.8e-13 50.4 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KKK11975.1 - 2.7e-08 33.1 0.0 6e-08 32.0 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 KKK11975.1 - 0.0019 17.8 0.0 0.011 15.2 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Pyr_redox_2 PF07992.9 KKK11976.1 - 4.6e-15 56.0 0.0 6.4e-15 55.5 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KKK11976.1 - 0.014 14.2 0.8 2 7.2 0.1 2.2 1 1 1 2 2 2 0 Glucose inhibited division protein A K_oxygenase PF13434.1 KKK11976.1 - 0.015 14.2 0.0 0.63 8.8 0.0 2.2 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.9 KKK11976.1 - 0.016 13.7 0.0 0.029 12.8 0.0 1.4 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_8 PF13450.1 KKK11976.1 - 0.031 14.3 0.1 0.14 12.1 0.0 2.2 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KKK11976.1 - 0.036 12.9 0.0 0.21 10.4 0.0 2.0 2 0 0 2 2 2 0 FAD binding domain Thi4 PF01946.12 KKK11976.1 - 0.039 13.0 0.0 0.087 11.9 0.0 1.5 2 0 0 2 2 2 0 Thi4 family NAD_binding_9 PF13454.1 KKK11976.1 - 0.84 9.3 4.1 1.9 8.2 0.1 2.7 2 1 0 3 3 3 0 FAD-NAD(P)-binding FLILHELTA PF10306.4 KKK11977.1 - 2.3e-27 94.8 0.2 1e-26 92.7 0.0 1.9 2 0 0 2 2 2 1 Hypothetical protein FLILHELTA DUF1279 PF06916.8 KKK11977.1 - 0.0021 18.3 0.0 0.0028 17.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) NDK PF00334.14 KKK11978.1 - 2.7e-55 185.8 0.0 3.1e-55 185.6 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase NUFIP1 PF10453.4 KKK11978.1 - 0.068 12.6 0.1 0.12 11.9 0.1 1.3 1 0 0 1 1 1 0 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) Glyco_hydro_31 PF01055.21 KKK11979.1 - 2.1e-146 488.2 5.8 3.1e-146 487.6 4.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 KKK11979.1 - 1.1e-24 86.0 0.3 6.8e-24 83.5 0.0 2.4 2 0 0 2 2 2 1 Galactose mutarotase-like Lipoprotein_18 PF06804.6 KKK11979.1 - 0.031 13.0 0.1 0.065 11.9 0.0 1.6 2 0 0 2 2 2 0 NlpB/DapX lipoprotein PQ-loop PF04193.9 KKK11980.1 - 1.9e-23 81.7 7.0 4.6e-15 54.9 0.2 3.2 3 0 0 3 3 3 2 PQ loop repeat ER_lumen_recept PF00810.13 KKK11980.1 - 0.065 13.7 2.5 0.35 11.3 0.4 2.1 2 0 0 2 2 2 0 ER lumen protein retaining receptor MTHFR PF02219.12 KKK11981.1 - 2e-100 335.6 0.0 2.8e-100 335.1 0.0 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase Epimerase PF01370.16 KKK11994.1 - 1.1e-23 83.9 0.0 1.4e-23 83.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KKK11994.1 - 2.7e-20 72.2 0.0 3.4e-20 71.8 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 KKK11994.1 - 1.3e-18 67.6 0.0 3.2e-18 66.3 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 KKK11994.1 - 3.6e-11 42.4 0.0 4.5e-11 42.1 0.0 1.1 1 0 0 1 1 1 1 Male sterility protein NmrA PF05368.8 KKK11994.1 - 1.6e-07 30.8 0.0 5.6e-07 29.0 0.0 1.9 2 0 0 2 2 2 1 NmrA-like family Polysacc_synt_2 PF02719.10 KKK11994.1 - 0.00015 20.7 0.0 0.00023 20.1 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.20 KKK11994.1 - 0.0034 17.3 0.0 0.0088 15.9 0.0 1.7 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KKK11994.1 - 0.027 14.1 0.0 0.045 13.4 0.0 1.4 1 0 0 1 1 1 0 KR domain HlyIII PF03006.15 KKK11995.1 - 1.3e-57 194.7 21.6 1.5e-57 194.5 15.0 1.1 1 0 0 1 1 1 1 Haemolysin-III related SPC12 PF06645.8 KKK11995.1 - 0.16 11.8 0.9 0.51 10.1 0.6 1.8 1 0 0 1 1 1 0 Microsomal signal peptidase 12 kDa subunit (SPC12) Fe-ADH PF00465.14 KKK11996.1 - 1.4e-33 116.0 3.7 2.2e-33 115.4 2.6 1.2 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fungal_trans PF04082.13 KKK11996.1 - 3e-15 55.7 0.5 4.5e-15 55.2 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fe-ADH_2 PF13685.1 KKK11996.1 - 2.9e-11 43.1 0.6 1.8e-10 40.5 0.3 2.0 2 0 0 2 2 2 1 Iron-containing alcohol dehydrogenase Zn_clus PF00172.13 KKK11996.1 - 1.1e-06 28.4 9.2 2e-06 27.6 6.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2HC5 PF06221.8 KKK12022.1 - 1.4e-21 75.9 4.9 2.2e-21 75.3 3.4 1.3 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type Sgf11 PF08209.6 KKK12023.1 - 2.8e-10 39.3 1.7 4.6e-10 38.6 0.1 2.0 2 0 0 2 2 2 1 Sgf11 (transcriptional regulation protein) zf-C2HC_2 PF13913.1 KKK12023.1 - 0.017 14.7 0.6 0.032 13.9 0.4 1.5 1 0 0 1 1 1 0 zinc-finger of a C2HC-type Tmemb_55A PF09788.4 KKK12023.1 - 0.38 9.8 5.0 0.12 11.5 1.3 1.7 1 1 1 2 2 2 0 Transmembrane protein 55A MFS_1 PF07690.11 KKK12024.1 - 5.7e-46 156.8 53.6 5.7e-46 156.8 37.2 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KKK12024.1 - 3.6e-10 38.6 23.5 4.5e-10 38.3 16.3 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Pacifastin_I PF05375.8 KKK12024.1 - 0.19 11.2 0.1 0.36 10.3 0.0 1.4 1 0 0 1 1 1 0 Pacifastin inhibitor (LCMII) Mpv17_PMP22 PF04117.7 KKK12025.1 - 2.4e-11 43.1 0.1 5.9e-11 41.8 0.1 1.7 1 0 0 1 1 1 1 Mpv17 / PMP22 family DUF1690 PF07956.6 KKK12026.1 - 1.7e-28 99.4 5.5 1.2e-14 54.4 0.4 2.1 2 0 0 2 2 2 2 Protein of Unknown function (DUF1690) Apolipoprotein PF01442.13 KKK12026.1 - 0.011 15.2 5.2 0.64 9.4 0.8 2.4 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain cwf21 PF08312.7 KKK12026.1 - 0.021 14.6 4.1 0.76 9.6 1.2 2.4 2 0 0 2 2 2 0 cwf21 domain Plasmid_RAQPRD PF09686.5 KKK12026.1 - 0.03 14.3 0.0 0.077 13.0 0.0 1.7 1 0 0 1 1 1 0 Plasmid protein of unknown function (Plasmid_RAQPRD) IFT57 PF10498.4 KKK12026.1 - 0.12 11.1 1.8 1.2 7.8 0.2 2.0 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 Phasin PF05597.6 KKK12026.1 - 0.21 11.3 4.4 0.18 11.5 0.4 2.1 2 0 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Matrilin_ccoil PF10393.4 KKK12026.1 - 0.95 8.8 5.7 11 5.4 1.1 2.4 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin Acetyltransf_1 PF00583.19 KKK12027.1 - 2.7e-05 24.1 0.0 0.0051 16.8 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family NAD_binding_6 PF08030.7 KKK12028.1 - 1e-19 70.9 0.0 1.2e-18 67.4 0.0 2.2 1 1 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 KKK12028.1 - 8.3e-19 67.9 12.1 1.9e-18 66.7 8.4 1.7 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 KKK12028.1 - 8.7e-15 54.4 0.0 1.6e-14 53.6 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.16 KKK12028.1 - 0.0022 18.5 0.0 0.35 11.4 0.0 2.4 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Hexokinase_2 PF03727.11 KKK12029.1 - 1.6e-72 243.6 0.0 2.1e-72 243.2 0.0 1.1 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 KKK12029.1 - 1.8e-63 213.6 0.0 2.5e-63 213.1 0.0 1.2 1 0 0 1 1 1 1 Hexokinase POP1 PF06978.6 KKK12030.1 - 4.5e-67 225.3 12.8 4.5e-67 225.3 8.8 2.2 3 0 0 3 3 3 1 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.7 KKK12030.1 - 1.1e-32 111.6 1.2 1.1e-32 111.6 0.9 2.3 2 0 0 2 2 2 1 POPLD (NUC188) domain Redoxin PF08534.5 KKK12031.1 - 1.5e-35 121.8 0.0 1.7e-35 121.7 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 KKK12031.1 - 1.3e-15 57.1 0.0 1.8e-15 56.7 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family DUF1348 PF07080.6 KKK12032.1 - 1.5e-44 151.2 2.7 2.1e-44 150.8 1.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1348) DUF4440 PF14534.1 KKK12032.1 - 5.6e-06 26.5 0.1 7.9e-06 26.0 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_2 PF12680.2 KKK12032.1 - 1.3e-05 25.5 0.3 4.4e-05 23.8 0.2 1.8 1 1 0 1 1 1 1 SnoaL-like domain Pkinase PF00069.20 KKK12033.1 - 4.4e-69 232.5 0.0 6.8e-69 231.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK12033.1 - 3.2e-35 121.4 0.0 1.5e-33 115.9 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KKK12033.1 - 8.6e-06 25.6 0.1 0.0026 17.5 0.0 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 KKK12033.1 - 0.00015 20.9 0.0 0.00028 20.0 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 KKK12033.1 - 0.0094 15.5 0.0 0.026 14.1 0.0 1.7 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kinase-like PF14531.1 KKK12033.1 - 0.014 14.3 0.0 0.032 13.1 0.0 1.5 1 0 0 1 1 1 0 Kinase-like Zn_clus PF00172.13 KKK12034.1 - 5.7e-09 35.7 7.4 8.1e-09 35.2 5.2 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_S10 PF00450.17 KKK12036.1 - 4.8e-92 309.2 3.0 1.2e-91 308.0 2.1 1.6 1 1 0 1 1 1 1 Serine carboxypeptidase Sugar_tr PF00083.19 KKK12037.1 - 6.2e-39 133.8 26.0 7.8e-22 77.4 7.1 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 KKK12037.1 - 4.8e-26 91.3 23.7 1.3e-18 66.8 9.7 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily Glucosamine_iso PF01182.15 KKK12038.1 - 2.8e-23 82.7 0.0 3.8e-23 82.2 0.0 1.2 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Sugar-bind PF04198.8 KKK12038.1 - 0.013 14.3 0.2 0.02 13.8 0.1 1.3 1 0 0 1 1 1 0 Putative sugar-binding domain Zn_clus PF00172.13 KKK12039.1 - 5.1e-06 26.3 8.8 8.6e-06 25.5 6.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Hexokinase_2 PF03727.11 KKK12040.1 - 4.6e-56 189.7 0.0 5.7e-42 143.5 0.0 2.3 2 0 0 2 2 2 2 Hexokinase Hexokinase_1 PF00349.16 KKK12040.1 - 7.1e-55 185.5 0.0 1.2e-54 184.7 0.0 1.3 1 0 0 1 1 1 1 Hexokinase Bac_rhamnosid PF05592.6 KKK12042.1 - 2.2e-182 606.8 0.0 2.6e-182 606.5 0.0 1.1 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase Bac_rhamnosid_N PF08531.5 KKK12042.1 - 2.5e-55 186.6 0.0 4.7e-55 185.7 0.0 1.5 1 0 0 1 1 1 1 Alpha-L-rhamnosidase N-terminal domain NAGLU PF05089.7 KKK12043.1 - 1.3e-130 435.0 7.6 1.7e-130 434.6 5.3 1.1 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain NAGLU_C PF12972.2 KKK12043.1 - 9.8e-70 234.9 1.8 1.5e-69 234.3 1.2 1.2 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain NAGLU_N PF12971.2 KKK12043.1 - 4.4e-16 58.3 0.0 9.2e-16 57.2 0.0 1.6 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain AA_permease_2 PF13520.1 KKK12045.1 - 1.1e-53 182.3 56.3 1.3e-53 182.0 39.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KKK12045.1 - 2e-20 72.6 46.7 2.6e-20 72.2 32.4 1.0 1 0 0 1 1 1 1 Amino acid permease Abhydrolase_3 PF07859.8 KKK12046.1 - 3.8e-10 39.7 0.0 5.2e-10 39.2 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 KKK12046.1 - 4.3e-10 38.9 0.5 2e-09 36.7 0.3 1.8 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 KKK12046.1 - 2.6e-07 30.4 0.0 3.7e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KKK12046.1 - 1.1e-05 25.3 0.0 1.7e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2424 PF10340.4 KKK12046.1 - 3e-05 22.8 0.0 4.6e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Chlorophyllase PF07224.6 KKK12046.1 - 0.00025 19.9 0.0 0.00035 19.4 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase Chlorophyllase2 PF12740.2 KKK12046.1 - 0.003 16.4 0.0 0.0048 15.8 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Glyco_hydro_30 PF02055.11 KKK12047.1 - 4.3e-44 150.5 1.8 6e-44 150.0 1.2 1.1 1 0 0 1 1 1 1 O-Glycosyl hydrolase family 30 CSS-motif PF12792.2 KKK12047.1 - 0.03 13.6 0.2 0.067 12.5 0.1 1.6 2 0 0 2 2 2 0 CSS motif domain associated with EAL Fungal_trans PF04082.13 KKK12049.1 - 6.2e-14 51.5 0.0 1.4e-13 50.3 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK12049.1 - 0.0014 18.5 14.3 0.0014 18.5 9.9 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DIOX_N PF14226.1 KKK12050.1 - 2.3e-19 70.0 0.1 4.8e-19 68.9 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KKK12050.1 - 7.1e-15 55.1 0.0 1.1e-14 54.4 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MFS_1 PF07690.11 KKK12051.1 - 3.4e-28 98.3 39.9 4.3e-28 98.0 25.8 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF1228 PF06779.9 KKK12051.1 - 8.4e-06 25.7 0.6 8.4e-06 25.7 0.4 3.0 3 0 0 3 3 3 1 Protein of unknown function (DUF1228) Kua-UEV1_localn PF10520.4 KKK12051.1 - 0.14 11.7 0.5 2.3 7.8 0.0 2.6 2 1 0 2 2 2 0 Kua-ubiquitin conjugating enzyme hybrid localisation domain FMN_dh PF01070.13 KKK12052.1 - 4.7e-106 354.6 0.2 1.4e-105 353.0 0.1 1.6 1 1 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 KKK12052.1 - 4.3e-22 77.7 0.0 8.7e-22 76.7 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain IMPDH PF00478.20 KKK12052.1 - 1.6e-05 24.0 0.1 3e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 KKK12052.1 - 2.9e-05 23.1 0.1 4.8e-05 22.4 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.10 KKK12052.1 - 0.0019 17.4 0.1 0.0039 16.3 0.1 1.5 1 0 0 1 1 1 1 Nitronate monooxygenase DHO_dh PF01180.16 KKK12052.1 - 0.036 13.0 0.0 0.065 12.1 0.0 1.3 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase His_biosynth PF00977.16 KKK12052.1 - 0.05 12.8 0.0 0.079 12.2 0.0 1.2 1 0 0 1 1 1 0 Histidine biosynthesis protein Ribul_P_3_epim PF00834.14 KKK12052.1 - 0.18 10.9 0.0 0.27 10.3 0.0 1.2 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family GMC_oxred_N PF00732.14 KKK12053.1 - 2.4e-55 187.7 0.0 3.2e-55 187.3 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KKK12053.1 - 1e-35 123.1 0.0 1.5e-35 122.5 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 KKK12053.1 - 1.5e-05 24.0 1.2 0.041 12.7 0.6 2.2 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.7 KKK12053.1 - 0.00047 19.1 0.2 0.0015 17.5 0.1 1.7 2 0 0 2 2 2 1 Lycopene cyclase protein DAO PF01266.19 KKK12053.1 - 0.0014 17.5 0.0 0.004 16.1 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KKK12053.1 - 0.0019 18.2 0.3 0.024 14.6 0.2 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KKK12053.1 - 0.0055 15.8 0.6 0.019 14.0 0.0 2.0 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.9 KKK12053.1 - 0.024 14.5 0.0 0.063 13.1 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Catalase PF00199.14 KKK12054.1 - 1.6e-168 560.3 0.0 2e-168 560.0 0.0 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 KKK12054.1 - 4.7e-14 52.0 0.0 1.1e-13 50.7 0.0 1.7 1 0 0 1 1 1 1 Catalase-related immune-responsive Peptidase_S10 PF00450.17 KKK12055.1 - 7.7e-95 318.4 0.1 1e-94 318.0 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Phosphoesterase PF04185.9 KKK12056.1 - 3.2e-75 253.6 4.1 4.4e-75 253.2 2.8 1.1 1 0 0 1 1 1 1 Phosphoesterase family Cu-oxidase_3 PF07732.10 KKK12057.1 - 3.9e-40 136.2 1.8 1.4e-38 131.1 0.0 3.2 4 0 0 4 4 4 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 KKK12057.1 - 5.9e-32 110.0 3.8 5e-31 107.0 0.1 3.1 2 1 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.17 KKK12057.1 - 4.2e-14 52.7 0.0 2.6e-13 50.1 0.0 2.2 2 0 0 2 2 2 1 Multicopper oxidase PhyH PF05721.8 KKK12058.1 - 2.2e-09 37.6 0.0 3.8e-09 36.8 0.0 1.4 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.7 KKK12058.1 - 5.4e-09 35.0 0.0 0.03 12.8 0.0 3.1 3 0 0 3 3 3 3 Protein of unknown function (DUF1479) Rad21_Rec8_N PF04825.8 KKK12150.1 - 9.8e-30 102.7 0.0 1.7e-29 101.9 0.0 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein FAD_binding_4 PF01565.18 KKK12152.1 - 6.3e-06 25.7 0.5 3e-05 23.5 0.3 2.1 2 0 0 2 2 2 1 FAD binding domain Peptidase_M29 PF02073.10 KKK12152.1 - 0.047 12.4 0.0 0.074 11.8 0.0 1.2 1 0 0 1 1 1 0 Thermophilic metalloprotease (M29) ADH_N PF08240.7 KKK12174.1 - 3.5e-23 81.4 0.4 6e-23 80.6 0.2 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KKK12174.1 - 2.1e-20 72.5 0.0 3.5e-20 71.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glyco_hydro_76 PF03663.9 KKK12175.1 - 1.5e-134 449.0 21.5 1.9e-134 448.7 14.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Tub_2 PF04525.7 KKK12176.1 - 1.6e-07 30.9 0.0 7.2e-07 28.7 0.0 2.0 1 1 0 1 1 1 1 Tubby C 2 zf-PARP PF00645.13 KKK12178.1 - 0.0051 17.0 0.0 0.01 16.0 0.0 1.5 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region Oxidored_FMN PF00724.15 KKK12179.1 - 5.2e-96 321.5 0.0 6e-96 321.4 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family APH PF01636.18 KKK12180.1 - 0.00088 19.0 0.0 0.0022 17.7 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family TFIIIC_sub6 PF10419.4 KKK12190.1 - 1.3e-16 59.7 0.1 2.6e-16 58.7 0.0 1.6 1 0 0 1 1 1 1 TFIIIC subunit DUF946 PF06101.6 KKK12191.1 - 2.7e-12 45.5 2.0 2.7e-12 45.4 0.4 1.7 2 0 0 2 2 2 1 Plant protein of unknown function (DUF946) JmjC PF02373.17 KKK12192.1 - 3.9e-09 36.7 0.0 3.6e-08 33.6 0.0 2.3 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.1 KKK12192.1 - 6.7e-09 35.6 0.0 1.5e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 Cupin-like domain PHD PF00628.24 KKK12192.1 - 1.9e-08 33.8 4.4 1.9e-08 33.8 3.1 2.7 3 0 0 3 3 3 1 PHD-finger PHD_2 PF13831.1 KKK12192.1 - 0.0037 16.5 4.4 0.0053 16.0 1.7 2.4 2 0 0 2 2 2 1 PHD-finger Dickkopf_N PF04706.7 KKK12192.1 - 0.31 11.2 11.3 3.6 7.8 1.7 2.9 2 0 0 2 2 2 0 Dickkopf N-terminal cysteine-rich region Zn_clus PF00172.13 KKK12192.1 - 2.6 8.0 28.3 0.13 12.1 3.6 3.2 3 0 0 3 3 3 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3661 PF12400.3 KKK12193.1 - 3e-42 143.7 4.0 5.5e-42 142.9 2.8 1.5 1 0 0 1 1 1 1 Vaculolar membrane protein RRM_1 PF00076.17 KKK12193.1 - 3.1e-18 65.1 0.3 4.9e-18 64.5 0.2 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KKK12193.1 - 3.9e-13 49.1 0.1 6.8e-13 48.4 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KKK12193.1 - 6.1e-09 35.6 0.1 1.1e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Flavokinase PF01687.12 KKK12194.1 - 1.8e-33 115.0 0.0 6.7e-33 113.2 0.0 1.8 1 1 0 1 1 1 1 Riboflavin kinase Zn_clus PF00172.13 KKK12195.1 - 0.0067 16.3 9.2 0.014 15.2 6.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS PF00989.19 KKK12195.1 - 0.062 13.0 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 PAS fold Menin PF05053.8 KKK12195.1 - 0.45 8.6 7.4 0.73 7.9 5.1 1.2 1 0 0 1 1 1 0 Menin PsbQ PF05757.6 KKK12195.1 - 1.6 8.1 5.7 2.9 7.2 4.0 1.3 1 0 0 1 1 1 0 Oxygen evolving enhancer protein 3 (PsbQ) MFS_1 PF07690.11 KKK12196.1 - 1e-42 146.1 31.6 1.2e-42 145.8 21.9 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 KKK12196.1 - 1.3e-07 30.2 3.0 2.6e-07 29.2 2.1 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.8 KKK12196.1 - 9.9e-05 20.6 0.5 0.00015 20.0 0.3 1.1 1 0 0 1 1 1 1 Transmembrane secretion effector Rad21_Rec8_N PF04825.8 KKK12197.1 - 9.1e-39 131.8 0.0 1.7e-38 130.9 0.0 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 KKK12197.1 - 4.4e-07 28.9 0.2 9.6e-07 27.8 0.1 1.5 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein ScpA_ScpB PF02616.9 KKK12197.1 - 0.00026 20.6 0.2 0.0048 16.5 0.0 2.3 2 0 0 2 2 2 1 ScpA/B protein E1-E2_ATPase PF00122.15 KKK12198.1 - 3.6e-80 268.2 0.2 6.8e-80 267.3 0.1 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KKK12198.1 - 1.1e-43 148.8 2.6 2.7e-43 147.5 0.0 2.4 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KKK12198.1 - 5.4e-30 105.4 0.0 5.6e-29 102.0 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KKK12198.1 - 6e-20 70.4 0.1 1.2e-19 69.5 0.1 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 KKK12198.1 - 3e-15 56.9 0.0 6.9e-15 55.7 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KKK12198.1 - 2.3e-14 53.0 0.0 4.7e-14 52.1 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KKK12198.1 - 2.1e-06 27.5 1.1 6.1e-05 22.7 0.6 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Ammonium_transp PF00909.16 KKK12199.1 - 4e-118 394.3 31.5 4.6e-118 394.1 21.8 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family COG4 PF08318.7 KKK12200.1 - 9.7e-110 366.4 0.0 1.4e-109 365.8 0.0 1.3 1 0 0 1 1 1 1 COG4 transport protein FA_desaturase PF00487.19 KKK12200.1 - 0.015 14.7 5.1 0.024 14.0 3.6 1.2 1 0 0 1 1 1 0 Fatty acid desaturase Zip PF02535.17 KKK12200.1 - 0.095 11.6 0.9 0.16 10.9 0.6 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter SIR2 PF02146.12 KKK12201.1 - 1.7e-55 187.5 0.0 2.3e-55 187.0 0.0 1.2 1 0 0 1 1 1 1 Sir2 family Nab1 PF04902.7 KKK12201.1 - 0.12 11.8 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 Conserved region in Nab1 Hexokinase_2 PF03727.11 KKK12202.1 - 1.9e-85 285.9 0.0 2.5e-85 285.5 0.0 1.1 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 KKK12202.1 - 1.5e-73 246.5 0.0 1.9e-73 246.1 0.0 1.1 1 0 0 1 1 1 1 Hexokinase PhnJ PF06007.6 KKK12202.1 - 0.024 13.3 0.0 0.038 12.7 0.0 1.2 1 0 0 1 1 1 0 Phosphonate metabolism protein PhnJ WD40 PF00400.27 KKK12203.1 - 5.1e-10 38.8 0.2 0.0057 16.5 0.0 4.9 5 0 0 5 5 5 3 WD domain, G-beta repeat DUF2583 PF10762.4 KKK12203.1 - 0.19 11.8 0.8 0.39 10.8 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2583) NAP PF00956.13 KKK12212.1 - 1e-45 155.7 12.1 1e-45 155.7 8.4 1.9 1 1 1 2 2 2 1 Nucleosome assembly protein (NAP) Med8 PF10232.4 KKK12212.1 - 0.011 15.2 0.0 0.024 14.1 0.0 1.6 1 0 0 1 1 1 0 Mediator of RNA polymerase II transcription complex subunit 8 Methyltransf_32 PF13679.1 KKK12213.1 - 1.2e-21 76.8 0.6 3.2e-21 75.4 0.4 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KKK12213.1 - 0.012 16.1 0.0 0.027 15.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 KKK12213.1 - 0.11 12.1 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Fungal_trans PF04082.13 KKK12214.1 - 6.7e-12 44.8 0.1 5.7e-11 41.7 0.0 2.4 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK12214.1 - 4e-09 36.2 13.3 7.5e-09 35.3 9.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain COX5A PF02284.11 KKK12215.1 - 4.2e-39 132.8 0.2 5.8e-39 132.3 0.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va LOH1CR12 PF10158.4 KKK12215.1 - 0.095 12.4 0.1 11 5.7 0.0 2.1 1 1 1 2 2 2 0 Tumour suppressor protein Glyco_transf_15 PF01793.11 KKK12216.1 - 3.7e-135 450.1 6.8 4.4e-135 449.8 4.7 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase NmrA PF05368.8 KKK12217.1 - 1.1e-61 208.0 0.0 1.9e-61 207.3 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KKK12217.1 - 4.9e-06 26.6 0.0 9.6e-06 25.7 0.0 1.5 2 0 0 2 2 2 1 NADH(P)-binding Syntaxin-6_N PF09177.6 KKK12219.1 - 2.9e-24 85.3 0.2 1.8e-23 82.7 0.0 2.1 2 0 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.14 KKK12219.1 - 4.9e-14 51.7 2.4 4.9e-14 51.7 1.6 2.8 3 0 0 3 3 3 1 SNARE domain Reo_sigmaC PF04582.7 KKK12219.1 - 0.089 11.9 0.1 0.62 9.1 0.0 1.9 2 0 0 2 2 2 0 Reovirus sigma C capsid protein IncA PF04156.9 KKK12219.1 - 0.18 11.3 0.0 0.18 11.3 0.0 3.0 3 0 0 3 3 3 0 IncA protein TBPIP PF07106.8 KKK12219.1 - 0.34 10.4 2.3 1.6 8.2 0.1 2.3 2 1 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF972 PF06156.8 KKK12219.1 - 0.72 10.2 3.4 5.5 7.3 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF972) DUF1515 PF07439.6 KKK12219.1 - 4.9 7.0 6.3 41 4.0 0.1 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1515) GATase_5 PF13507.1 KKK12220.1 - 1.2e-98 329.1 0.0 1.9e-98 328.5 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.17 KKK12220.1 - 2e-42 144.7 0.4 1.5e-20 73.7 0.1 2.8 3 0 0 3 3 3 2 AIR synthase related protein, C-terminal domain AIRS PF00586.19 KKK12220.1 - 2.7e-26 91.6 0.4 2.1e-25 88.8 0.0 2.5 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain Spc97_Spc98 PF04130.8 KKK12221.1 - 3.8e-80 269.7 10.3 3.8e-80 269.7 7.2 1.5 2 0 0 2 2 2 1 Spc97 / Spc98 family GCP5-Mod21 PF14609.1 KKK12221.1 - 2.3e-07 29.3 0.1 8.2e-07 27.5 0.0 1.9 2 0 0 2 2 2 1 gamma-Tubulin ring complex non-core subunit mod21 Sigma70_ner PF04546.8 KKK12221.1 - 0.0026 17.4 3.6 0.0064 16.1 2.5 1.6 1 0 0 1 1 1 1 Sigma-70, non-essential region TFIIA PF03153.8 KKK12221.1 - 0.007 16.3 1.2 0.011 15.7 0.9 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit CENP-B_dimeris PF09026.5 KKK12221.1 - 0.019 15.1 7.4 0.049 13.8 5.1 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain TRAP_alpha PF03896.11 KKK12221.1 - 0.12 11.3 1.2 0.25 10.3 0.9 1.5 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit NOA36 PF06524.7 KKK12221.1 - 0.28 10.4 7.8 0.42 9.8 5.4 1.2 1 0 0 1 1 1 0 NOA36 protein BTV_NS2 PF04514.7 KKK12221.1 - 0.37 9.6 3.6 0.75 8.6 2.5 1.4 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Fungal_trans PF04082.13 KKK12222.1 - 2.5e-09 36.3 0.4 5e-09 35.4 0.3 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK12222.1 - 3e-06 27.0 11.8 5.3e-06 26.2 8.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Med3 PF11593.3 KKK12222.1 - 4.7 6.3 13.3 10 5.2 9.2 1.5 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal MFS_1 PF07690.11 KKK12223.1 - 4.6e-43 147.2 32.6 4.6e-43 147.2 22.6 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KKK12223.1 - 2.2e-10 39.7 11.3 2.2e-10 39.7 7.8 2.6 2 2 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 KKK12223.1 - 2.1e-09 36.1 2.1 4.1e-09 35.2 1.4 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) AA_permease_2 PF13520.1 KKK12224.1 - 1.3e-40 139.2 51.1 1.8e-40 138.8 35.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KKK12224.1 - 7.5e-19 67.4 39.4 1.3e-18 66.6 27.2 1.3 1 1 0 1 1 1 1 Amino acid permease PNTB PF02233.11 KKK12225.1 - 1.1e-171 571.6 22.3 1.1e-171 571.6 15.4 1.5 2 0 0 2 2 2 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.16 KKK12225.1 - 2.9e-50 170.0 0.5 6e-50 169.0 0.4 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.10 KKK12225.1 - 9.6e-46 155.1 0.0 2.2e-45 153.9 0.0 1.7 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain DUF3814 PF12769.2 KKK12225.1 - 3.6e-30 103.9 3.8 3.6e-30 103.9 2.6 5.3 5 2 2 7 7 6 1 Domain of unknown function (DUF3814) 2-Hacid_dh_C PF02826.14 KKK12225.1 - 1.6e-05 24.1 0.3 0.15 11.2 0.0 2.7 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N PF00107.21 KKK12225.1 - 0.0015 18.0 0.1 0.0051 16.3 0.1 2.0 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_31 PF13847.1 KKK12225.1 - 0.0071 15.9 0.0 0.058 12.9 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain TPP_enzyme_M PF00205.17 KKK12225.1 - 0.029 14.1 0.5 0.23 11.1 0.2 2.7 2 1 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain Pyr_redox_2 PF07992.9 KKK12225.1 - 0.042 13.7 0.5 0.11 12.4 0.1 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_18 PF12847.2 KKK12225.1 - 0.044 14.3 0.0 0.14 12.7 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain Shikimate_DH PF01488.15 KKK12225.1 - 1.2 9.1 10.0 4.1 7.4 0.0 4.5 5 1 0 5 5 5 0 Shikimate / quinate 5-dehydrogenase ELO PF01151.13 KKK12227.1 - 7.4e-63 212.1 20.9 8.6e-63 211.9 14.5 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family adh_short_C2 PF13561.1 KKK12228.1 - 2.7e-31 109.2 0.0 3.5e-31 108.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KKK12228.1 - 2.1e-30 105.8 0.0 2.8e-30 105.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KKK12228.1 - 7.3e-08 32.2 0.0 1.8e-07 30.9 0.0 1.6 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 KKK12228.1 - 0.0022 17.4 0.0 0.0077 15.6 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 KKK12228.1 - 0.0096 15.6 0.1 0.02 14.6 0.1 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DFP PF04127.10 KKK12228.1 - 0.072 12.6 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein 3Beta_HSD PF01073.14 KKK12228.1 - 0.087 11.5 0.1 0.13 10.8 0.1 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family AdoHcyase_NAD PF00670.16 KKK12228.1 - 0.092 12.5 0.1 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Fungal_trans_2 PF11951.3 KKK12229.1 - 2.5e-36 125.0 0.2 3.2e-36 124.7 0.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK12229.1 - 6.7e-09 35.5 8.2 1.2e-08 34.7 5.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ATP-synt_DE_N PF02823.11 KKK12231.1 - 2.4e-18 65.6 0.1 3.8e-18 65.0 0.1 1.4 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain Cytochrom_B561 PF03188.11 KKK12232.1 - 2.2e-05 24.2 7.6 0.00077 19.2 7.0 2.2 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 ABA_WDS PF02496.11 KKK12232.1 - 0.46 10.6 3.5 12 6.2 0.1 3.3 4 0 0 4 4 4 0 ABA/WDS induced protein DUF998 PF06197.8 KKK12232.1 - 1.8 7.8 19.7 0.087 12.1 5.2 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF998) Glyco_transf_90 PF05686.7 KKK12233.1 - 2e-12 46.5 0.7 3.2e-09 35.9 0.1 3.2 3 0 0 3 3 3 3 Glycosyl transferase family 90 Ribosomal_L29e PF01779.12 KKK12234.1 - 1.3e-09 37.7 0.4 1.3e-09 37.7 0.2 1.6 2 0 0 2 2 2 1 Ribosomal L29e protein family PQ-loop PF04193.9 KKK12235.1 - 2.5e-38 129.4 8.8 1.1e-19 69.6 1.1 2.5 2 0 0 2 2 2 2 PQ loop repeat ATG27 PF09451.5 KKK12235.1 - 0.042 13.0 0.6 0.061 12.5 0.4 1.2 1 0 0 1 1 1 0 Autophagy-related protein 27 NfeD PF01957.13 KKK12235.1 - 0.047 13.8 0.6 0.68 10.0 0.1 2.4 2 1 0 2 2 2 0 NfeD-like C-terminal, partner-binding DUF2374 PF09574.5 KKK12235.1 - 0.55 9.8 4.3 2.9 7.5 0.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (Duf2374) zf-C2H2_4 PF13894.1 KKK12236.1 - 4.3e-07 29.8 11.9 0.091 13.1 0.1 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.21 KKK12236.1 - 0.00039 20.6 7.4 0.01 16.1 0.0 3.4 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2 PF00096.21 KKK12237.1 - 7e-08 32.3 11.9 0.00063 19.9 2.4 3.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KKK12237.1 - 1.6e-05 24.8 11.0 0.0011 19.1 1.2 3.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KKK12237.1 - 1.7e-05 24.8 4.3 1.7e-05 24.8 3.0 4.2 4 0 0 4 4 4 1 Zinc-finger double domain BCNT PF07572.7 KKK12238.1 - 5.2e-28 96.7 0.3 5.2e-28 96.7 0.2 1.9 2 0 0 2 2 2 1 Bucentaur or craniofacial development Glyco_hydro_28 PF00295.12 KKK12240.1 - 2.1e-111 371.9 17.5 2.4e-111 371.7 12.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Ribonuclease_T2 PF00445.13 KKK12241.1 - 8e-46 156.0 2.2 1.2e-45 155.4 1.5 1.2 1 0 0 1 1 1 1 Ribonuclease T2 family DUF1792 PF08759.6 KKK12241.1 - 0.045 13.3 0.4 0.08 12.5 0.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF1792) bZIP_1 PF00170.16 KKK12242.1 - 1.8e-06 27.7 0.8 3.7e-06 26.7 0.6 1.5 1 0 0 1 1 1 1 bZIP transcription factor Chorion_2 PF03964.10 KKK12242.1 - 0.012 16.1 2.9 0.012 16.1 2.0 2.1 2 0 0 2 2 2 0 Chorion family 2 DUF3446 PF11928.3 KKK12242.1 - 0.37 11.0 10.5 0.13 12.4 4.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3446) FliD_N PF02465.13 KKK12242.1 - 0.6 10.5 10.5 1.6 9.1 0.2 2.4 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus DUF504 PF04457.7 KKK12243.1 - 3.6e-10 39.8 0.1 7.9e-10 38.7 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF504) MIF PF01187.13 KKK12243.1 - 4.6e-07 29.9 0.4 7.2e-07 29.2 0.3 1.3 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) Macro PF01661.16 KKK12244.1 - 3e-10 40.0 0.0 1.2e-09 38.0 0.0 1.9 1 1 0 1 1 1 1 Macro domain Claudin_2 PF13903.1 KKK12245.1 - 0.0008 19.1 9.1 0.42 10.2 2.3 3.6 1 1 3 4 4 4 3 PMP-22/EMP/MP20/Claudin tight junction DUF3611 PF12263.3 KKK12245.1 - 0.01 15.2 0.2 1.5 8.1 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3611) DUF202 PF02656.10 KKK12245.1 - 0.035 14.3 1.8 0.035 14.3 1.2 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF202) DUF4395 PF14340.1 KKK12245.1 - 0.036 14.1 6.8 0.017 15.1 1.9 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4395) MARVEL PF01284.18 KKK12245.1 - 0.53 10.1 5.2 1.8 8.3 3.6 1.9 1 1 0 1 1 1 0 Membrane-associating domain Amidohydro_4 PF13147.1 KKK12246.1 - 2.4e-10 40.8 0.0 3e-10 40.5 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_2 PF04909.9 KKK12246.1 - 1.7e-07 31.1 0.1 3.3e-07 30.1 0.1 1.6 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 KKK12246.1 - 0.00062 19.5 0.1 0.0031 17.1 0.1 1.9 1 1 0 1 1 1 1 Amidohydrolase family Mis12 PF05859.7 KKK12247.1 - 1e-44 151.8 0.0 2e-44 150.9 0.0 1.5 1 0 0 1 1 1 1 Mis12 protein Dus PF01207.12 KKK12248.1 - 1.8e-54 184.6 0.0 2.9e-54 183.9 0.0 1.3 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) DHO_dh PF01180.16 KKK12248.1 - 0.018 14.0 0.0 0.028 13.4 0.0 1.2 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase CENP-X PF09415.5 KKK12249.1 - 3.9e-28 97.0 0.0 7.1e-28 96.2 0.0 1.4 1 0 0 1 1 1 1 CENP-S associating Centromere protein X Dicty_REP PF05086.7 KKK12249.1 - 1.2 6.7 8.3 1.3 6.6 5.8 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein TFIIA PF03153.8 KKK12249.1 - 4 7.2 7.9 4.5 7.0 5.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Fungal_trans PF04082.13 KKK12250.1 - 1.3e-13 50.4 0.6 3.1e-13 49.2 0.4 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 KKK12250.1 - 2.7e-07 30.5 15.4 0.0013 18.9 1.5 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KKK12250.1 - 1.7e-06 28.0 8.8 1.7e-06 28.0 6.1 3.8 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 KKK12250.1 - 1.2e-05 25.2 12.1 0.02 15.1 0.7 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.2 KKK12250.1 - 0.00012 22.1 8.9 0.084 13.1 0.7 2.5 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KKK12250.1 - 0.0017 18.4 11.2 0.039 14.1 2.7 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 KKK12250.1 - 0.013 15.3 7.9 0.03 14.2 0.3 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2HC_2 PF13913.1 KKK12250.1 - 8 6.2 9.7 21 4.9 2.5 2.7 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Collagen PF01391.13 KKK12251.1 - 6.6 6.3 15.2 4.8 6.7 1.5 2.4 2 0 0 2 2 2 0 Collagen triple helix repeat (20 copies) Vps52 PF04129.7 KKK12252.1 - 1.5e-111 373.4 0.0 2e-111 373.0 0.0 1.1 1 0 0 1 1 1 1 Vps52 / Sac2 family DAO PF01266.19 KKK12252.1 - 2.2e-34 118.9 0.0 4e-34 118.0 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Sec8_exocyst PF04048.9 KKK12252.1 - 0.0094 15.5 0.1 0.026 14.1 0.1 1.7 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain CorA PF01544.13 KKK12252.1 - 0.62 9.0 3.0 0.9 8.5 0.1 2.1 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein eIF-5a PF01287.15 KKK12253.1 - 2.4e-21 75.4 1.1 2.4e-21 75.4 0.8 1.8 2 0 0 2 2 2 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold KOW PF00467.24 KKK12253.1 - 8.6e-05 22.1 1.5 0.0003 20.3 1.0 2.0 1 0 0 1 1 1 1 KOW motif EFP_N PF08207.7 KKK12253.1 - 0.072 12.9 0.2 0.2 11.5 0.0 1.9 2 0 0 2 2 2 0 Elongation factor P (EF-P) KOW-like domain DNA_repr_REX1B PF14966.1 KKK12255.1 - 0.027 14.8 0.1 0.071 13.4 0.0 1.7 2 1 0 2 2 2 0 DNA repair REX1-B Spc7 PF08317.6 KKK12255.1 - 0.032 12.8 0.0 0.045 12.3 0.0 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Fmp27_WPPW PF10359.4 KKK12255.1 - 0.11 10.8 0.0 0.14 10.5 0.0 1.0 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Pyr_redox_2 PF07992.9 KKK12256.1 - 7.8e-22 78.1 1.9 2.4e-10 40.6 0.0 3.1 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KKK12256.1 - 7.5e-20 71.1 2.1 4.2e-15 55.9 0.0 2.7 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase Rhodanese PF00581.15 KKK12256.1 - 4.9e-12 46.1 0.0 1.5e-11 44.6 0.0 1.8 2 0 0 2 2 1 1 Rhodanese-like domain FAD_binding_2 PF00890.19 KKK12256.1 - 1.5e-08 33.9 2.8 1.9e-05 23.6 0.0 2.6 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 KKK12256.1 - 5.3e-08 32.1 5.6 0.00032 19.7 0.0 3.3 3 0 0 3 3 3 2 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.16 KKK12256.1 - 1.9e-07 30.8 0.7 0.00038 20.0 0.0 2.5 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_8 PF13450.1 KKK12256.1 - 1.9e-07 30.9 5.2 0.0013 18.6 0.4 3.0 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 KKK12256.1 - 1.6e-05 24.0 6.6 0.23 10.3 0.1 3.4 2 1 1 3 3 3 3 Lycopene cyclase protein HI0933_like PF03486.9 KKK12256.1 - 1.9e-05 23.3 9.1 0.081 11.3 0.7 3.3 2 1 1 3 3 3 2 HI0933-like protein TrkA_N PF02254.13 KKK12256.1 - 3.6e-05 23.7 0.7 0.0039 17.1 0.0 2.4 2 0 0 2 2 2 1 TrkA-N domain Pyr_redox_dim PF02852.17 KKK12256.1 - 4.8e-05 23.3 0.0 0.00016 21.6 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain XdhC_C PF13478.1 KKK12256.1 - 0.00041 20.6 0.1 0.11 12.8 0.0 2.6 2 0 0 2 2 2 1 XdhC Rossmann domain GIDA PF01134.17 KKK12256.1 - 0.00043 19.2 1.9 0.022 13.6 0.3 2.3 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 KKK12256.1 - 0.0013 18.8 4.2 0.32 11.0 0.2 2.8 1 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 KKK12256.1 - 0.0019 18.3 0.1 1.2 9.4 0.0 2.5 2 0 0 2 2 2 1 Putative NAD(P)-binding 3HCDH_N PF02737.13 KKK12256.1 - 0.0029 17.2 0.9 0.0054 16.3 0.0 1.8 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_oxidored PF12831.2 KKK12256.1 - 0.0035 16.4 1.6 0.0035 16.4 1.1 2.6 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 KKK12256.1 - 0.013 14.5 4.6 0.098 11.6 0.2 2.3 2 0 0 2 2 2 0 FAD binding domain 2-Hacid_dh_C PF02826.14 KKK12256.1 - 0.013 14.6 1.0 0.024 13.8 0.0 1.8 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Thi4 PF01946.12 KKK12256.1 - 0.015 14.4 1.0 3.2 6.8 0.0 2.3 2 0 0 2 2 2 0 Thi4 family CPSase_L_chain PF00289.17 KKK12256.1 - 0.024 14.7 0.2 0.41 10.7 0.0 2.5 2 0 0 2 2 2 0 Carbamoyl-phosphate synthase L chain, N-terminal domain F420_oxidored PF03807.12 KKK12256.1 - 0.072 13.5 1.4 5 7.6 0.0 2.5 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.18 KKK12256.1 - 0.17 11.5 0.3 4.2 7.0 0.0 2.3 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Trp_halogenase PF04820.9 KKK12256.1 - 0.62 8.6 5.4 0.81 8.2 0.5 2.1 2 0 0 2 2 2 0 Tryptophan halogenase NAD_binding_9 PF13454.1 KKK12256.1 - 2.7 7.7 8.1 4.1 7.1 0.2 3.2 2 1 1 3 3 3 0 FAD-NAD(P)-binding tRNA-synt_2 PF00152.15 KKK12257.1 - 3.8e-69 233.0 0.0 5e-69 232.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) DUF2156 PF09924.4 KKK12257.1 - 2.4e-12 46.3 0.0 3.6e-12 45.7 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2156) tRNA-synt_2d PF01409.15 KKK12257.1 - 0.00067 18.9 0.3 0.049 12.8 0.0 2.8 3 0 0 3 3 3 1 tRNA synthetases class II core domain (F) tRNA_anti-codon PF01336.20 KKK12257.1 - 0.0023 17.7 0.0 0.0045 16.8 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2b PF00587.20 KKK12257.1 - 0.12 11.8 0.0 22 4.5 0.0 2.7 3 0 0 3 3 3 0 tRNA synthetase class II core domain (G, H, P, S and T) RRM_1 PF00076.17 KKK12258.1 - 3.8e-80 263.5 4.1 1e-20 73.1 0.1 5.3 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KKK12258.1 - 2.1e-53 178.1 0.6 8.5e-14 51.2 0.0 5.3 5 0 0 5 5 5 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KKK12258.1 - 3.6e-40 135.6 0.2 2.6e-09 36.7 0.0 5.5 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 KKK12258.1 - 4e-31 106.4 2.4 9.3e-31 105.3 0.8 2.3 3 0 0 3 3 3 1 Poly-adenylate binding protein, unique domain Nup35_RRM_2 PF14605.1 KKK12258.1 - 1.3e-05 24.8 0.1 1.3 8.8 0.0 4.4 4 0 0 4 4 4 1 Nup53/35/40-type RNA recognition motif CbiG_mid PF11761.3 KKK12258.1 - 0.00038 20.6 4.0 0.74 10.0 0.0 3.9 5 0 0 5 5 5 2 Cobalamin biosynthesis central region Limkain-b1 PF11608.3 KKK12258.1 - 0.018 14.8 5.5 13 5.6 0.0 3.7 3 0 0 3 3 3 0 Limkain b1 CSD PF00313.17 KKK12258.1 - 0.02 14.6 1.1 45 3.9 0.0 3.6 3 0 0 3 3 3 0 'Cold-shock' DNA-binding domain OB_RNB PF08206.6 KKK12258.1 - 0.041 13.3 1.5 7 6.2 0.0 3.5 3 0 0 3 3 3 0 Ribonuclease B OB domain Fungal_trans PF04082.13 KKK12259.1 - 2.1e-17 62.8 4.5 2.2e-15 56.2 3.1 2.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain APH PF01636.18 KKK12260.1 - 6.8e-06 25.9 1.4 0.0012 18.6 0.4 2.8 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 KKK12260.1 - 2.2e-05 23.6 0.1 4.6e-05 22.5 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 KKK12260.1 - 0.016 14.8 0.0 0.039 13.5 0.0 1.6 1 0 0 1 1 1 0 Choline/ethanolamine kinase U79_P34 PF03064.11 KKK12260.1 - 0.048 13.1 5.8 0.094 12.2 4.0 1.4 1 0 0 1 1 1 0 HSV U79 / HCMV P34 DUF3523 PF12037.3 KKK12260.1 - 0.078 11.9 11.2 0.14 11.0 7.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3523) HECT PF00632.20 KKK12261.1 - 1.1e-84 284.3 0.0 1.6e-84 283.7 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Trypan_PARP PF05887.6 KKK12262.1 - 0.069 12.9 6.4 0.093 12.5 4.4 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Mito_fiss_reg PF05308.6 KKK12262.1 - 1.9 7.7 6.4 2.8 7.2 4.4 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator CoA_trans PF01144.18 KKK12263.1 - 4.7e-97 323.3 1.5 3.6e-58 196.2 0.2 2.0 2 0 0 2 2 2 2 Coenzyme A transferase DUF531 PF04407.7 KKK12263.1 - 0.083 12.7 0.0 0.23 11.3 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF531) AhpC-TSA PF00578.16 KKK12265.1 - 4.2e-32 110.4 0.0 5.7e-32 110.0 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family 1-cysPrx_C PF10417.4 KKK12265.1 - 1.1e-13 50.5 0.1 1.8e-13 49.9 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Redoxin PF08534.5 KKK12265.1 - 4.9e-12 45.6 0.0 6.3e-12 45.2 0.0 1.2 1 0 0 1 1 1 1 Redoxin AMP-binding PF00501.23 KKK12266.1 - 1.4e-64 218.0 0.3 2.2e-64 217.4 0.2 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.15 KKK12266.1 - 1.5e-45 155.3 0.1 3.8e-45 154.0 0.1 1.6 1 1 0 1 1 1 1 Condensation domain NAD_binding_4 PF07993.7 KKK12266.1 - 2e-29 102.2 0.0 1.4e-27 96.2 0.0 2.7 1 1 0 1 1 1 1 Male sterility protein PP-binding PF00550.20 KKK12266.1 - 6.6e-25 87.1 0.3 2e-14 53.5 0.0 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site HxxPF_rpt PF13745.1 KKK12266.1 - 2e-11 44.0 0.1 7.2e-11 42.2 0.1 2.0 1 0 0 1 1 1 1 HxxPF-repeated domain NAD_binding_10 PF13460.1 KKK12266.1 - 0.00055 19.9 0.0 0.085 12.8 0.0 2.5 2 0 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 KKK12266.1 - 0.00072 19.0 0.0 0.0034 16.8 0.0 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KKK12266.1 - 0.046 12.4 0.0 0.086 11.5 0.0 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Hydantoinase_B PF02538.9 KKK12268.1 - 8.2e-191 634.7 0.0 1e-190 634.4 0.0 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.13 KKK12268.1 - 2.2e-92 309.2 0.1 3.5e-91 305.3 0.0 2.2 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 KKK12268.1 - 5.8e-54 182.2 0.0 2.1e-51 173.9 0.0 2.5 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region Methyltransf_11 PF08241.7 KKK12275.1 - 3e-08 34.0 0.0 6.2e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KKK12275.1 - 8e-07 29.4 0.0 1.8e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KKK12275.1 - 1e-06 28.5 0.0 1.9e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KKK12275.1 - 0.0011 18.5 0.0 0.0026 17.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Dynactin_p62 PF05502.8 KKK12276.1 - 1.1e-189 631.2 0.0 1.7e-189 630.6 0.0 1.3 1 0 0 1 1 1 1 Dynactin p62 family Sporozoite_P67 PF05642.6 KKK12276.1 - 0.11 10.3 5.6 0.21 9.3 3.9 1.4 1 0 0 1 1 1 0 Sporozoite P67 surface antigen FdhE PF04216.7 KKK12276.1 - 0.28 10.8 6.6 0.57 9.8 4.6 1.5 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation DUF2162 PF09930.4 KKK12276.1 - 0.3 10.1 0.4 0.53 9.3 0.2 1.3 1 0 0 1 1 1 0 Predicted transporter (DUF2162) DUF4611 PF15387.1 KKK12276.1 - 3.6 7.7 13.6 0.37 10.9 5.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) TRAP_alpha PF03896.11 KKK12276.1 - 6.5 5.6 6.2 12 4.8 4.3 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Ribosomal_S7e PF01251.13 KKK12277.1 - 2.5e-84 281.5 0.2 3e-84 281.2 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S7e P16-Arc PF04699.9 KKK12278.1 - 4.2e-59 198.9 0.0 5.1e-59 198.6 0.0 1.1 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) Cupin_2 PF07883.6 KKK12284.1 - 8.2e-07 28.4 0.0 1.4e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.7 KKK12284.1 - 0.033 13.5 0.0 0.083 12.2 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF861) Cupin_6 PF12852.2 KKK12284.1 - 0.13 11.8 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 Cupin RRF PF01765.14 KKK12295.1 - 0.031 13.7 2.7 0.05 13.0 1.9 1.2 1 0 0 1 1 1 0 Ribosome recycling factor Rubella_E2 PF05749.6 KKK12295.1 - 0.08 12.1 7.0 0.15 11.2 4.8 1.4 1 0 0 1 1 1 0 Rubella membrane glycoprotein E2 His_Phos_1 PF00300.17 KKK12296.1 - 2.4e-12 47.2 0.0 5.4e-12 46.0 0.0 1.6 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) DUF1248 PF06852.7 KKK12296.1 - 0.089 12.0 0.1 0.21 10.8 0.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1248) Ank_2 PF12796.2 KKK12297.1 - 7.8e-103 337.0 20.6 1.5e-22 79.7 0.2 8.5 3 2 6 9 9 9 8 Ankyrin repeats (3 copies) Ank PF00023.25 KKK12297.1 - 2.2e-84 273.3 11.9 9.6e-11 40.9 0.0 15.2 14 1 1 15 15 15 13 Ankyrin repeat Ank_4 PF13637.1 KKK12297.1 - 2.8e-78 257.0 9.9 2e-12 47.2 0.0 10.9 7 2 4 11 11 11 10 Ankyrin repeats (many copies) Ank_3 PF13606.1 KKK12297.1 - 5.7e-77 245.8 5.2 1.2e-06 28.2 0.0 16.4 17 0 0 17 17 17 13 Ankyrin repeat Ank_5 PF13857.1 KKK12297.1 - 7e-67 219.9 21.3 1.4e-08 34.6 0.0 14.5 4 2 11 15 15 15 14 Ankyrin repeats (many copies) CorA PF01544.13 KKK12297.1 - 0.0012 17.9 4.3 0.0013 17.8 1.3 2.0 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein FAM195 PF14799.1 KKK12297.1 - 0.1 12.4 0.0 0.3 10.9 0.0 1.7 1 0 0 1 1 1 0 FAM195 family Glyco_hydro_43 PF04616.9 KKK12298.1 - 1.2e-43 149.3 8.9 5.7e-37 127.3 0.7 2.0 2 0 0 2 2 2 2 Glycosyl hydrolases family 43 Pkinase PF00069.20 KKK12299.1 - 1.2e-75 254.0 0.0 1.4e-75 253.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK12299.1 - 7.7e-38 130.0 0.0 9.4e-38 129.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KKK12299.1 - 4.2e-07 29.2 0.0 5.4e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KKK12299.1 - 0.0065 15.5 0.1 0.011 14.7 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KKK12299.1 - 0.0075 16.0 0.0 0.019 14.7 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 KKK12299.1 - 0.073 11.8 0.0 0.16 10.7 0.0 1.5 1 0 0 1 1 1 0 Seadornavirus VP7 Fe-ADH PF00465.14 KKK12300.1 - 3.1e-99 332.0 0.1 3.8e-99 331.7 0.1 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 KKK12300.1 - 1.2e-16 60.7 0.0 2.6e-13 49.8 0.0 2.2 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Peripla_BP_6 PF13458.1 KKK12300.1 - 0.00017 21.0 0.0 0.00027 20.3 0.0 1.3 1 0 0 1 1 1 1 Periplasmic binding protein Toprim_3 PF13362.1 KKK12300.1 - 0.056 13.6 0.0 0.2 11.9 0.0 1.8 2 0 0 2 2 2 0 Toprim domain Arylsulfotran_2 PF14269.1 KKK12301.1 - 3e-110 368.0 5.4 3.6e-110 367.7 3.7 1.1 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.6 KKK12301.1 - 0.00014 20.5 4.7 0.00053 18.6 3.2 1.7 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) Bys1 PF04681.7 KKK12302.1 - 2.5e-08 33.7 0.0 2.8e-08 33.6 0.0 1.1 1 0 0 1 1 1 1 Blastomyces yeast-phase-specific protein BNR_2 PF13088.1 KKK12303.1 - 1.7e-05 24.2 0.0 0.016 14.5 0.0 2.2 1 1 1 2 2 2 2 BNR repeat-like domain BNR PF02012.15 KKK12303.1 - 0.00011 21.5 5.9 0.017 14.8 0.1 3.6 3 0 0 3 3 3 2 BNR/Asp-box repeat zf-C2H2_2 PF12756.2 KKK12304.1 - 5.1e-39 132.4 10.8 1.4e-31 108.5 1.9 3.4 3 0 0 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 KKK12304.1 - 4.2e-07 29.9 19.2 5.8e-07 29.4 3.8 4.4 4 1 0 4 4 4 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KKK12304.1 - 1.6e-05 24.8 4.5 1.6e-05 24.8 3.1 3.3 4 0 0 4 4 4 1 Zinc-finger of C2H2 type zf-LYAR PF08790.6 KKK12304.1 - 0.0038 16.8 0.5 0.0038 16.8 0.3 2.2 2 0 0 2 2 2 1 LYAR-type C2HC zinc finger DUF2024 PF09630.5 KKK12304.1 - 0.047 13.3 3.7 4.4 7.0 0.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF2024) zf-C2H2 PF00096.21 KKK12304.1 - 0.14 12.5 18.7 0.16 12.4 0.3 4.4 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 KKK12304.1 - 0.17 11.8 7.5 1.9 8.5 0.5 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger HECT PF00632.20 KKK12305.1 - 1.6e-75 254.2 0.0 2.4e-75 253.6 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) FAD_binding_3 PF01494.14 KKK12306.1 - 4.6e-22 78.5 0.0 6.8e-22 77.9 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 KKK12306.1 - 3.9e-07 29.3 10.6 0.0023 16.9 3.6 3.3 3 0 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KKK12306.1 - 3.8e-05 23.6 2.6 0.0003 20.7 1.8 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KKK12306.1 - 9.3e-05 21.5 0.0 0.00017 20.6 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 KKK12306.1 - 0.00014 20.8 4.1 0.00014 20.8 2.8 2.2 3 0 0 3 3 3 1 FAD binding domain NAD_binding_8 PF13450.1 KKK12306.1 - 0.00034 20.5 1.4 0.00034 20.5 1.0 1.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 KKK12306.1 - 0.0014 17.2 3.7 0.012 14.1 1.1 2.1 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.17 KKK12306.1 - 0.0054 15.6 3.2 0.015 14.1 2.2 1.6 1 1 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 KKK12306.1 - 0.0078 16.2 0.1 0.013 15.5 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KKK12306.1 - 0.029 13.4 0.2 0.029 13.4 0.2 1.6 2 0 0 2 2 2 0 Thi4 family AlaDh_PNT_C PF01262.16 KKK12306.1 - 0.052 13.1 0.6 0.094 12.2 0.4 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.2 KKK12306.1 - 0.058 12.4 4.4 0.33 9.9 3.0 2.0 1 1 0 1 1 1 0 FAD dependent oxidoreductase Trp_halogenase PF04820.9 KKK12306.1 - 0.075 11.6 3.2 5.2 5.5 0.0 2.6 3 0 0 3 3 3 0 Tryptophan halogenase Pyr_redox PF00070.22 KKK12306.1 - 0.27 11.6 4.7 1.9 8.9 1.5 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Peptidase_M20 PF01546.23 KKK12308.1 - 7.8e-23 80.9 0.0 1.7e-21 76.6 0.0 2.8 2 1 0 2 2 2 1 Peptidase family M20/M25/M40 WD40 PF00400.27 KKK12308.1 - 4.5e-11 42.1 3.2 0.09 12.7 0.1 5.7 4 1 0 4 4 4 3 WD domain, G-beta repeat M20_dimer PF07687.9 KKK12308.1 - 1e-05 25.2 0.0 2e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 KKK12308.1 - 0.0037 17.0 0.0 0.011 15.5 0.0 1.8 1 0 0 1 1 1 1 Peptidase family M28 PQQ_3 PF13570.1 KKK12308.1 - 0.034 14.4 0.6 12 6.3 0.0 4.1 3 0 0 3 3 3 0 PQQ-like domain SpdB PF05122.8 KKK12308.1 - 0.034 14.1 0.5 0.034 14.1 0.3 2.1 2 0 0 2 2 2 0 Mobile element transfer protein Shisa PF13908.1 KKK12308.1 - 3.3 7.8 7.5 0.81 9.8 2.2 2.0 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator DUF747 PF05346.6 KKK12309.1 - 6.6e-130 432.9 4.2 9e-130 432.5 2.9 1.1 1 0 0 1 1 1 1 Eukaryotic membrane protein family Cas_TM1802 PF09484.5 KKK12310.1 - 0.27 9.7 0.0 0.37 9.2 0.0 1.1 1 0 0 1 1 1 0 CRISPR-associated protein TM1802 (cas_TM1802) Pyr_redox_3 PF13738.1 KKK12311.1 - 1.2e-18 67.9 1.6 1e-09 38.7 0.0 3.0 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KKK12311.1 - 1.5e-11 43.2 2.6 4.4e-09 35.0 0.1 3.0 1 1 1 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 KKK12311.1 - 3e-08 33.5 0.0 7.7e-08 32.2 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KKK12311.1 - 9.4e-06 24.7 0.1 0.00038 19.4 0.0 2.4 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KKK12311.1 - 9.5e-06 25.6 0.0 0.065 13.1 0.0 3.6 1 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KKK12311.1 - 3.9e-05 22.7 0.1 0.045 12.6 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.12 KKK12311.1 - 0.001 18.2 0.1 0.0017 17.4 0.1 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.1 KKK12311.1 - 0.0035 17.1 0.0 0.014 15.2 0.0 2.0 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 KKK12311.1 - 0.0095 14.8 0.1 0.015 14.2 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 KKK12311.1 - 0.017 14.0 0.0 0.038 12.9 0.0 1.6 1 0 0 1 1 1 0 Lycopene cyclase protein CCDC155 PF14662.1 KKK12312.1 - 0.005 16.4 6.9 0.005 16.4 4.8 4.4 2 1 2 4 4 4 1 Coiled-coil region of CCDC155 ApoC-I PF04691.7 KKK12312.1 - 0.015 14.9 0.3 0.048 13.3 0.2 1.9 1 0 0 1 1 1 0 Apolipoprotein C-I (ApoC-1) IKKbetaNEMObind PF12179.3 KKK12312.1 - 0.91 9.4 6.0 14 5.5 0.1 3.6 3 0 0 3 3 3 0 I-kappa-kinase-beta NEMO binding domain DUF3496 PF12001.3 KKK12312.1 - 2.1 8.6 21.6 0.84 9.9 1.0 4.4 3 1 0 4 4 4 0 Domain of unknown function (DUF3496) Laminin_I PF06008.9 KKK12312.1 - 3.5 6.8 39.5 0.037 13.3 2.6 4.7 1 1 3 4 4 4 0 Laminin Domain I DUF4201 PF13870.1 KKK12312.1 - 9.3 5.6 36.9 0.078 12.4 0.4 4.7 2 1 0 4 4 4 0 Domain of unknown function (DUF4201) DUF21 PF01595.15 KKK12313.1 - 1.8e-31 108.8 0.3 3.3e-31 107.9 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF21 CBS PF00571.23 KKK12313.1 - 6.3e-08 32.2 0.4 0.014 15.1 0.0 3.1 2 0 0 2 2 2 2 CBS domain SPT6_acidic PF14632.1 KKK12313.1 - 0.17 12.0 4.4 1.4 9.1 0.5 2.8 3 0 0 3 3 3 0 Acidic N-terminal SPT6 Arginosuc_synth PF00764.14 KKK12314.1 - 3.5e-142 474.0 0.0 8.1e-142 472.8 0.0 1.5 1 1 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.8 KKK12314.1 - 4.2e-05 22.9 0.0 6.7e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC Asn_synthase PF00733.16 KKK12314.1 - 0.00015 21.3 0.0 0.00021 20.8 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase tRNA_Me_trans PF03054.11 KKK12314.1 - 0.014 13.9 0.0 0.021 13.3 0.0 1.3 1 0 0 1 1 1 0 tRNA methyl transferase p450 PF00067.17 KKK12315.1 - 7e-74 249.0 0.0 8.9e-74 248.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 SGL PF08450.7 KKK12315.1 - 8e-30 104.0 0.0 1.5e-29 103.1 0.0 1.3 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Arylesterase PF01731.15 KKK12315.1 - 0.00012 21.9 0.0 0.00036 20.4 0.0 1.8 1 0 0 1 1 1 1 Arylesterase NHL PF01436.16 KKK12315.1 - 0.0067 16.3 0.6 0.43 10.6 0.0 2.9 2 0 0 2 2 2 1 NHL repeat Str_synth PF03088.11 KKK12315.1 - 0.14 12.1 0.0 1 9.4 0.0 2.3 2 1 0 2 2 2 0 Strictosidine synthase GST_N_3 PF13417.1 KKK12316.1 - 2.4e-09 37.2 0.0 4.9e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KKK12316.1 - 1.2e-08 34.7 0.0 2.7e-08 33.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 KKK12316.1 - 2.4e-07 30.8 0.0 3e-05 24.1 0.0 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KKK12316.1 - 3e-06 27.1 0.0 5.2e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KKK12316.1 - 0.00079 19.2 0.1 0.0015 18.3 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Asparaginase_2 PF01112.13 KKK12317.1 - 2e-06 26.7 0.0 3.8e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Asparaginase Tim17 PF02466.14 KKK12318.1 - 4.5e-34 117.2 7.0 5.8e-34 116.8 4.9 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family UPF0126 PF03458.8 KKK12318.1 - 2.5 7.7 6.9 21 4.7 1.1 3.1 1 1 2 4 4 4 0 UPF0126 domain Zn_clus PF00172.13 KKK12319.1 - 5.2e-06 26.2 7.1 1.1e-05 25.1 4.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.7 KKK12319.1 - 0.73 10.0 6.8 9 6.5 0.8 2.5 2 0 0 2 2 2 0 Dickkopf N-terminal cysteine-rich region Peptidase_M3 PF01432.15 KKK12341.1 - 3.2e-110 369.3 0.0 4.2e-110 368.9 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M50B PF13398.1 KKK12341.1 - 0.094 12.0 0.2 0.2 11.0 0.1 1.4 1 0 0 1 1 1 0 Peptidase M50B-like Peptidase_M91 PF14891.1 KKK12341.1 - 0.17 11.9 0.0 0.31 11.1 0.0 1.4 1 0 0 1 1 1 0 Effector protein TPR_MLP1_2 PF07926.7 KKK12342.1 - 0.00032 20.4 6.4 0.00032 20.4 4.4 10.6 2 2 8 10 10 10 4 TPR/MLP1/MLP2-like protein Apolipoprotein PF01442.13 KKK12342.1 - 0.00036 20.1 31.4 0.00036 20.1 21.8 6.9 1 1 6 7 7 7 1 Apolipoprotein A1/A4/E domain Spc7 PF08317.6 KKK12342.1 - 0.0011 17.6 16.0 0.0011 17.6 11.1 8.2 1 1 7 8 8 8 3 Spc7 kinetochore protein Filament PF00038.16 KKK12342.1 - 0.0028 17.1 173.9 0.012 15.1 18.9 8.8 2 1 6 8 8 8 4 Intermediate filament protein Tropomyosin_1 PF12718.2 KKK12342.1 - 0.0035 17.1 19.2 0.0035 17.1 13.3 9.4 1 1 7 8 8 8 1 Tropomyosin like IncA PF04156.9 KKK12342.1 - 0.0051 16.4 14.0 0.0051 16.4 9.7 8.9 2 1 7 9 9 9 1 IncA protein Fib_alpha PF08702.5 KKK12342.1 - 0.0054 16.8 10.9 0.0054 16.8 7.5 9.8 1 1 7 10 10 10 3 Fibrinogen alpha/beta chain family GRASP55_65 PF04495.9 KKK12343.1 - 2.6e-40 137.6 0.0 1.2e-37 128.9 0.0 2.2 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain DUF2360 PF10152.4 KKK12343.1 - 7.4 6.8 8.0 20 5.4 5.6 1.7 1 1 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) ApoO PF09769.4 KKK12344.1 - 9.4e-52 174.9 0.2 6.9e-51 172.0 0.1 1.9 2 0 0 2 2 2 1 Apolipoprotein O 4HBT_3 PF13622.1 KKK12344.1 - 0.029 14.1 2.2 0.033 13.9 1.5 1.1 1 0 0 1 1 1 0 Thioesterase-like superfamily Mito_fiss_reg PF05308.6 KKK12344.1 - 2.7 7.2 10.6 4.1 6.7 7.4 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator DUF3591 PF12157.3 KKK12345.1 - 1.8e-196 652.9 0.0 2.3e-196 652.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) zf-CCHC_6 PF15288.1 KKK12345.1 - 0.0034 17.0 1.1 0.0078 15.8 0.8 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 KKK12345.1 - 0.015 15.2 0.9 0.025 14.5 0.6 1.4 1 0 0 1 1 1 0 Zinc knuckle Methyltransf_15 PF09445.5 KKK12346.1 - 5.1e-51 172.4 0.0 6.4e-51 172.1 0.0 1.1 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Met_10 PF02475.11 KKK12346.1 - 1.4e-12 47.5 0.0 1.9e-12 47.2 0.0 1.1 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_26 PF13659.1 KKK12346.1 - 1.7e-09 37.7 0.0 2.3e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 KKK12346.1 - 1e-06 28.4 0.0 1.3e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_18 PF12847.2 KKK12346.1 - 1.4e-06 28.8 0.0 1.9e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.10 KKK12346.1 - 2.2e-05 23.9 0.0 3.2e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_31 PF13847.1 KKK12346.1 - 0.00021 20.9 0.0 0.00024 20.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KKK12346.1 - 0.092 12.1 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain DNA_methylase PF00145.12 KKK12346.1 - 0.1 11.7 0.0 0.19 10.8 0.0 1.5 1 1 0 1 1 1 0 C-5 cytosine-specific DNA methylase PrmA PF06325.8 KKK12346.1 - 0.15 11.1 0.0 0.22 10.5 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Pkinase PF00069.20 KKK12347.1 - 7.1e-46 156.4 0.1 2.8e-23 82.3 0.0 3.3 3 0 0 3 3 3 3 Protein kinase domain FKBP_C PF00254.23 KKK12347.1 - 1.2e-30 105.4 0.0 2.4e-30 104.3 0.0 1.6 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Pkinase_Tyr PF07714.12 KKK12347.1 - 7.9e-19 67.7 0.0 1e-10 41.1 0.0 3.0 3 0 0 3 3 3 2 Protein tyrosine kinase APH PF01636.18 KKK12347.1 - 0.00019 21.2 0.5 0.00047 19.9 0.4 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family PTPA PF03095.10 KKK12348.1 - 3.1e-114 381.2 0.0 3.5e-114 380.9 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein DUF572 PF04502.8 KKK12349.1 - 5.2e-09 35.7 8.6 6.8e-09 35.3 6.0 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF572) SgrR_N PF12793.2 KKK12349.1 - 0.02 14.9 0.6 0.46 10.4 0.1 2.3 2 0 0 2 2 2 0 Sugar transport-related sRNA regulator N-term SR-25 PF10500.4 KKK12349.1 - 6.3 6.1 20.1 10 5.5 13.4 1.9 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein APH PF01636.18 KKK12372.1 - 2.9e-09 37.0 2.3 3.2e-08 33.6 0.3 2.8 2 1 0 2 2 2 1 Phosphotransferase enzyme family Lectin_leg-like PF03388.8 KKK12373.1 - 2.5e-12 46.4 0.0 2.9e-12 46.1 0.0 1.1 1 0 0 1 1 1 1 Legume-like lectin family ATG27 PF09451.5 KKK12373.1 - 0.036 13.3 0.0 0.036 13.2 0.0 1.1 1 0 0 1 1 1 0 Autophagy-related protein 27 PRCC PF10253.4 KKK12374.1 - 7.9e-43 147.2 6.7 7.9e-43 147.2 4.6 3.0 3 1 0 3 3 3 1 Mitotic checkpoint regulator, MAD2B-interacting Nucleic_acid_bd PF13820.1 KKK12374.1 - 0.047 13.2 0.3 0.18 11.3 0.0 2.0 2 0 0 2 2 2 0 Putative nucleic acid-binding region ARS2 PF04959.8 KKK12374.1 - 0.062 13.4 0.2 0.062 13.4 0.1 2.2 2 0 0 2 2 2 0 Arsenite-resistance protein 2 DUF1777 PF08648.7 KKK12375.1 - 0.092 12.4 31.9 0.59 9.8 11.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1777) Voltage_CLC PF00654.15 KKK12376.1 - 1.8e-69 234.4 23.5 2.5e-69 234.0 16.3 1.1 1 0 0 1 1 1 1 Voltage gated chloride channel CTK3 PF12243.3 KKK12376.1 - 1.5e-58 196.3 0.1 2.4e-58 195.7 0.1 1.3 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 CTK3_C PF12350.3 KKK12376.1 - 6.4e-20 70.9 5.0 1.5e-19 69.8 3.4 1.7 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 C-terminus CBS PF00571.23 KKK12376.1 - 0.022 14.5 0.0 0.16 11.7 0.0 2.2 2 0 0 2 2 2 0 CBS domain MAM33 PF02330.11 KKK12376.1 - 0.16 11.6 0.1 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial glycoprotein AAA_5 PF07728.9 KKK12377.1 - 7.1e-131 430.7 0.7 4.5e-22 78.2 0.0 10.0 8 1 1 9 9 9 9 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 KKK12377.1 - 5.2e-29 100.5 0.0 1e-10 41.3 0.0 7.6 8 0 0 8 8 7 3 ATPase family associated with various cellular activities (AAA) AAA PF00004.24 KKK12377.1 - 3.6e-26 91.9 0.0 3.8e-05 23.8 0.0 7.3 6 0 0 6 6 6 5 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 KKK12377.1 - 3.6e-24 85.2 0.0 0.00055 19.8 0.0 8.3 8 2 0 8 8 6 4 AAA domain AAA_14 PF13173.1 KKK12377.1 - 3e-20 72.4 0.0 0.00025 20.9 0.0 7.8 7 1 0 8 8 6 3 AAA domain AAA_16 PF13191.1 KKK12377.1 - 1e-19 71.2 17.0 0.00099 19.1 0.0 8.8 9 0 0 9 9 6 4 AAA ATPase domain AAA_22 PF13401.1 KKK12377.1 - 1.2e-19 70.7 1.4 0.033 14.3 0.0 8.6 8 1 0 8 8 8 4 AAA domain AAA_17 PF13207.1 KKK12377.1 - 2.4e-19 70.3 0.0 0.0024 18.6 0.0 7.4 6 0 0 6 6 6 2 AAA domain AAA_18 PF13238.1 KKK12377.1 - 3.2e-17 63.0 0.5 0.011 15.9 0.0 7.4 6 0 0 6 6 6 3 AAA domain ABC_tran PF00005.22 KKK12377.1 - 4.3e-15 56.2 2.1 0.04 14.2 0.0 7.0 7 0 0 7 7 7 3 ABC transporter Sigma54_activat PF00158.21 KKK12377.1 - 7.3e-15 54.8 0.0 0.0086 15.5 0.1 6.2 6 0 0 6 6 6 3 Sigma-54 interaction domain Zeta_toxin PF06414.7 KKK12377.1 - 9.4e-15 54.2 0.4 0.078 12.0 0.0 7.3 6 0 0 6 6 6 3 Zeta toxin Sigma54_activ_2 PF14532.1 KKK12377.1 - 8.7e-14 51.7 0.5 0.0025 17.8 0.1 6.6 7 0 0 7 7 6 2 Sigma-54 interaction domain UPF0079 PF02367.12 KKK12377.1 - 2e-12 46.8 4.3 0.027 14.0 0.0 6.4 6 0 0 6 6 6 3 Uncharacterised P-loop hydrolase UPF0079 Mg_chelatase PF01078.16 KKK12377.1 - 4.8e-12 45.4 2.6 3.1 6.9 0.1 9.2 9 1 1 10 10 10 0 Magnesium chelatase, subunit ChlI Arch_ATPase PF01637.13 KKK12377.1 - 1.6e-11 44.4 0.3 1.7 8.3 0.0 6.7 6 0 0 6 6 6 2 Archaeal ATPase NACHT PF05729.7 KKK12377.1 - 2.4e-11 43.5 5.4 0.12 12.0 0.1 5.3 4 0 0 4 4 4 3 NACHT domain RNA_helicase PF00910.17 KKK12377.1 - 2.9e-11 43.4 1.6 1.1 9.5 0.0 6.7 6 0 0 6 6 6 2 RNA helicase MobB PF03205.9 KKK12377.1 - 3e-11 43.1 1.8 0.35 10.5 0.0 6.5 6 0 0 6 6 6 2 Molybdopterin guanine dinucleotide synthesis protein B Miro PF08477.8 KKK12377.1 - 6.3e-11 42.8 3.7 0.32 11.5 0.1 6.8 6 0 0 6 6 6 1 Miro-like protein T2SE PF00437.15 KKK12377.1 - 7.1e-11 41.5 2.0 0.58 8.9 0.0 6.1 6 0 0 6 6 6 2 Type II/IV secretion system protein AAA_29 PF13555.1 KKK12377.1 - 2.4e-10 39.7 3.6 0.38 10.2 0.0 6.6 6 0 0 6 6 6 2 P-loop containing region of AAA domain AAA_19 PF13245.1 KKK12377.1 - 4.6e-10 39.1 6.4 0.048 13.4 0.1 6.4 6 0 0 6 6 6 2 Part of AAA domain PduV-EutP PF10662.4 KKK12377.1 - 5.7e-10 38.8 4.1 0.065 12.7 0.0 6.1 6 0 0 6 6 6 3 Ethanolamine utilisation - propanediol utilisation DUF258 PF03193.11 KKK12377.1 - 5.8e-10 38.5 2.6 0.19 10.8 0.1 6.2 6 0 0 6 6 6 2 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 KKK12377.1 - 6e-10 39.0 0.5 0.067 13.1 0.0 6.5 6 0 0 6 6 6 1 50S ribosome-binding GTPase AAA_28 PF13521.1 KKK12377.1 - 6.4e-10 39.2 4.9 0.032 14.1 0.1 6.5 6 0 0 6 6 6 2 AAA domain SRP54 PF00448.17 KKK12377.1 - 6.6e-10 38.7 5.9 0.036 13.4 0.0 5.9 6 0 0 6 6 5 2 SRP54-type protein, GTPase domain AAA_25 PF13481.1 KKK12377.1 - 1.8e-09 37.2 3.9 0.24 10.7 0.0 6.2 6 0 0 6 6 5 2 AAA domain DUF815 PF05673.8 KKK12377.1 - 2.5e-09 36.4 1.7 0.24 10.2 0.1 5.8 6 0 0 6 6 6 2 Protein of unknown function (DUF815) RuvB_N PF05496.7 KKK12377.1 - 4.8e-09 35.6 3.0 0.1 11.6 0.0 6.3 7 0 0 7 7 7 2 Holliday junction DNA helicase ruvB N-terminus Bac_DnaA PF00308.13 KKK12377.1 - 1e-06 28.5 0.0 0.41 10.2 0.0 4.0 4 0 0 4 4 3 2 Bacterial dnaA protein SRPRB PF09439.5 KKK12377.1 - 5.6e-06 25.6 2.0 3.8 6.7 0.0 5.7 6 0 0 6 6 5 0 Signal recognition particle receptor beta subunit IstB_IS21 PF01695.12 KKK12377.1 - 7.8e-06 25.4 0.3 2.6 7.4 0.0 5.2 5 0 0 5 5 5 0 IstB-like ATP binding protein NTPase_1 PF03266.10 KKK12377.1 - 1.3e-05 25.0 8.0 0.35 10.5 0.1 5.3 5 0 0 5 5 5 2 NTPase AAA_7 PF12775.2 KKK12377.1 - 2.1e-05 23.7 0.6 2 7.4 0.0 4.8 5 0 0 5 5 5 1 P-loop containing dynein motor region D3 Viral_helicase1 PF01443.13 KKK12377.1 - 2.3e-05 24.0 0.0 0.33 10.4 0.0 4.7 4 0 0 4 4 4 1 Viral (Superfamily 1) RNA helicase Rad17 PF03215.10 KKK12377.1 - 7.2e-05 21.6 1.6 1.8 7.1 0.0 4.8 5 0 0 5 5 5 1 Rad17 cell cycle checkpoint protein ATP_bind_1 PF03029.12 KKK12377.1 - 7.4e-05 22.3 3.0 2.4 7.6 0.0 5.5 5 0 0 5 5 5 1 Conserved hypothetical ATP binding protein cobW PF02492.14 KKK12377.1 - 0.00011 21.7 5.4 5.9 6.2 0.0 5.9 6 0 0 6 6 6 0 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.1 KKK12377.1 - 0.00011 21.8 0.2 23 4.4 0.0 5.5 6 0 0 6 6 5 0 AAA domain NB-ARC PF00931.17 KKK12377.1 - 0.00011 21.1 1.8 15 4.3 0.1 4.7 4 0 0 4 4 4 0 NB-ARC domain MCM PF00493.18 KKK12377.1 - 0.00017 20.5 0.3 5.9 5.5 0.0 4.5 5 0 0 5 5 4 0 MCM2/3/5 family CPT PF07931.7 KKK12377.1 - 0.00056 19.5 1.4 2.9 7.4 0.0 5.5 6 1 0 6 6 4 0 Chloramphenicol phosphotransferase-like protein TIP49 PF06068.8 KKK12377.1 - 0.00058 18.6 4.6 0.11 11.1 0.0 5.0 6 0 0 6 6 6 1 TIP49 C-terminus ATP-synt_ab PF00006.20 KKK12377.1 - 0.0027 17.2 0.0 24 4.3 0.0 4.1 4 0 0 4 4 4 0 ATP synthase alpha/beta family, nucleotide-binding domain FeoB_N PF02421.13 KKK12377.1 - 0.004 16.4 5.3 2.4 7.3 0.0 5.4 6 0 0 6 6 5 1 Ferrous iron transport protein B KaiC PF06745.8 KKK12377.1 - 0.004 16.2 0.3 30 3.6 0.0 4.8 5 0 0 5 5 5 0 KaiC AAA_15 PF13175.1 KKK12377.1 - 0.006 15.6 0.0 7.6 5.4 0.0 3.7 4 0 0 4 4 4 0 AAA ATPase domain ResIII PF04851.10 KKK12377.1 - 0.033 14.0 12.2 0.42 10.4 0.0 4.8 6 0 0 6 6 3 0 Type III restriction enzyme, res subunit CbiA PF01656.18 KKK12377.1 - 0.035 13.5 2.4 4 6.7 0.1 3.9 4 0 0 4 4 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_6 PF12774.2 KKK12377.1 - 0.042 13.3 0.0 18 4.7 0.0 3.8 3 0 0 3 3 3 0 Hydrolytic ATP binding site of dynein motor region D1 KTI12 PF08433.5 KKK12377.1 - 0.043 13.0 0.9 20 4.3 0.0 4.3 5 0 0 5 5 3 0 Chromatin associated protein KTI12 Septin PF00735.13 KKK12377.1 - 0.055 12.4 1.9 6.7 5.6 0.1 3.6 4 0 0 4 4 4 0 Septin ArgK PF03308.11 KKK12377.1 - 0.067 11.9 6.5 0.49 9.1 0.2 3.8 5 0 0 5 5 5 0 ArgK protein PRK PF00485.13 KKK12377.1 - 0.078 12.5 0.1 3.6 7.0 0.0 3.4 4 0 0 4 4 3 0 Phosphoribulokinase / Uridine kinase family PhoH PF02562.11 KKK12377.1 - 0.32 10.1 2.1 5.7 6.1 0.0 3.5 4 0 0 4 4 4 0 PhoH-like protein DUF155 PF02582.9 KKK12378.1 - 1.2e-52 178.3 0.2 2.2e-52 177.5 0.1 1.4 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 U3_snoRNA_assoc PF08297.6 KKK12378.1 - 2.5e-21 75.6 1.0 2.5e-21 75.6 0.7 3.6 3 0 0 3 3 3 1 U3 snoRNA associated adh_short PF00106.20 KKK12379.1 - 1.1e-22 80.7 0.3 1.5e-22 80.2 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KKK12379.1 - 1.8e-18 67.2 0.2 2.2e-18 66.9 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 KKK12379.1 - 3.8e-07 30.2 0.1 7.1e-07 29.4 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding KR PF08659.5 KKK12379.1 - 4.7e-06 26.3 0.3 8e-06 25.6 0.2 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 KKK12379.1 - 4.8e-05 22.9 0.0 7e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.5 KKK12379.1 - 0.013 14.6 0.0 6.1 5.8 0.0 2.6 2 1 0 2 2 2 0 Fungal family of unknown function (DUF1776) PAE PF03283.8 KKK12379.1 - 0.017 13.7 0.1 0.023 13.3 0.1 1.2 1 0 0 1 1 1 0 Pectinacetylesterase 3Beta_HSD PF01073.14 KKK12379.1 - 0.04 12.6 0.0 0.066 11.9 0.0 1.5 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 KKK12379.1 - 0.043 13.0 0.0 0.072 12.3 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family RmlD_sub_bind PF04321.12 KKK12379.1 - 0.051 12.4 0.0 0.082 11.7 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain ADH_zinc_N PF00107.21 KKK12379.1 - 0.083 12.4 0.1 0.28 10.7 0.0 2.0 1 1 0 1 1 1 0 Zinc-binding dehydrogenase Histone PF00125.19 KKK12394.1 - 1.9e-15 56.7 0.3 2.3e-15 56.4 0.2 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 KKK12394.1 - 4.9e-05 23.4 0.1 6.6e-05 23.0 0.1 1.3 1 1 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 KKK12394.1 - 7.1e-05 22.6 0.2 0.0001 22.1 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 KKK12394.1 - 0.00011 22.2 0.1 0.00019 21.4 0.1 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 KKK12394.1 - 0.0026 17.4 0.0 0.0031 17.1 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated CENP-T PF15511.1 KKK12394.1 - 0.011 14.9 0.0 0.012 14.9 0.0 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T TFIID_20kDa PF03847.8 KKK12394.1 - 0.049 13.9 0.0 0.1 12.9 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A Lipase_GDSL PF00657.17 KKK12395.1 - 4.5e-14 52.8 0.0 6e-14 52.4 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 KKK12395.1 - 4.2e-13 49.8 0.1 6.4e-13 49.2 0.1 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL_3 PF14606.1 KKK12395.1 - 0.03 14.0 0.1 3.3 7.4 0.0 2.3 2 0 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family MAT1 PF06391.8 KKK12395.1 - 0.073 12.6 0.0 0.11 12.0 0.0 1.1 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 CBM_21 PF03370.8 KKK12396.1 - 1.2e-35 121.9 3.2 2e-35 121.1 2.2 1.4 1 0 0 1 1 1 1 Putative phosphatase regulatory subunit CBM_25 PF03423.8 KKK12396.1 - 0.55 10.3 4.6 2.3 8.3 3.2 1.9 1 1 0 1 1 1 0 Carbohydrate binding domain (family 25) WD40 PF00400.27 KKK12397.1 - 3.2e-05 23.6 3.1 1.1 9.2 0.0 6.1 7 0 0 7 7 7 1 WD domain, G-beta repeat GshA PF08886.6 KKK12397.1 - 0.21 9.8 0.0 0.31 9.2 0.0 1.1 1 0 0 1 1 1 0 Glutamate-cysteine ligase Nucleoporin_FG PF13634.1 KKK12398.1 - 2.8e-09 37.2 105.5 3.8e-07 30.3 37.7 3.4 1 1 2 3 3 3 3 Nucleoporin FG repeat region DUF1664 PF07889.7 KKK12398.1 - 0.016 14.9 0.2 1.5 8.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Annexin PF00191.15 KKK12399.1 - 2.6e-59 196.9 3.2 4.7e-17 61.6 0.0 4.1 4 0 0 4 4 4 4 Annexin DUF1645 PF07816.6 KKK12399.1 - 0.11 12.9 0.0 0.19 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1645) SapB_1 PF05184.10 KKK12399.1 - 0.17 11.7 0.1 0.32 10.8 0.1 1.4 1 0 0 1 1 1 0 Saposin-like type B, region 1 Mito_carr PF00153.22 KKK12400.1 - 1.2e-35 121.0 9.2 1.2e-14 53.7 0.0 4.1 4 0 0 4 4 3 3 Mitochondrial carrier protein zf-C3HC4 PF00097.20 KKK12400.1 - 2.4e-07 30.2 5.4 2.4e-07 30.2 3.8 3.8 4 1 0 4 4 2 1 Zinc finger, C3HC4 type (RING finger) SH3_9 PF14604.1 KKK12400.1 - 8.4e-07 28.4 0.1 2.9e-06 26.7 0.1 1.9 2 0 0 2 2 2 1 Variant SH3 domain zf-C3HC4_2 PF13923.1 KKK12400.1 - 3e-06 27.1 5.9 3e-06 27.1 4.1 3.9 4 0 0 4 4 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 KKK12400.1 - 4.2e-06 26.4 0.5 4.2e-06 26.4 0.4 2.5 2 0 0 2 2 1 1 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.1 KKK12400.1 - 9.9e-05 22.1 7.1 9.9e-05 22.1 4.9 3.4 3 0 0 3 3 2 1 zinc finger of C3HC4-type, RING SH3_1 PF00018.23 KKK12400.1 - 0.0016 17.7 0.2 0.0035 16.7 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KKK12400.1 - 0.01 15.2 0.3 0.033 13.6 0.0 2.0 2 0 0 2 2 2 0 Variant SH3 domain Tmpp129 PF10272.4 KKK12400.1 - 0.057 12.1 1.9 0.12 11.0 1.3 1.4 1 0 0 1 1 1 0 Putative transmembrane protein precursor DUF883 PF05957.8 KKK12400.1 - 0.074 13.4 0.3 0.074 13.4 0.2 3.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Neisseria_TspB PF05616.8 KKK12400.1 - 6.4 5.0 8.6 11 4.2 5.9 1.3 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein Fip1 PF05182.8 KKK12402.1 - 9.8e-21 72.7 2.1 1.6e-20 72.0 1.4 1.4 1 0 0 1 1 1 1 Fip1 motif Cpn10 PF00166.16 KKK12402.1 - 6.1e-14 51.7 0.0 7.2e-07 29.0 0.0 2.4 1 1 1 2 2 2 2 Chaperonin 10 Kd subunit Ribosomal_60s PF00428.14 KKK12402.1 - 0.88 10.0 7.5 2.8 8.3 4.0 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein Rpr2 PF04032.11 KKK12403.1 - 2.9e-06 27.0 0.3 2.9e-06 27.0 0.2 1.7 2 0 0 2 2 2 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain CDC27 PF09507.5 KKK12403.1 - 0.34 10.0 5.3 0.48 9.6 3.6 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DBR1 PF05011.8 KKK12404.1 - 2.4e-50 170.1 0.9 4.5e-50 169.3 0.0 1.9 2 0 0 2 2 2 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.23 KKK12404.1 - 8.8e-12 44.8 0.2 1.9e-11 43.7 0.2 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase DUF2435 PF10363.4 KKK12405.1 - 1.5e-26 92.0 0.1 2.1e-25 88.4 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2435) DUF2411 PF10304.4 KKK12405.1 - 2.7e-11 42.6 0.0 7.3e-11 41.3 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF2411) zf-ZPR1 PF03367.8 KKK12406.1 - 2.9e-96 319.1 0.1 2.4e-48 163.3 0.0 2.2 2 0 0 2 2 2 2 ZPR1 zinc-finger domain zf-ribbon_3 PF13248.1 KKK12406.1 - 2.4 7.4 7.4 0.42 9.8 1.9 2.2 2 0 0 2 2 2 0 zinc-ribbon domain Cytochrome_C7 PF14522.1 KKK12406.1 - 5.6 6.6 7.4 3 7.5 1.1 2.6 2 1 1 3 3 3 0 Cytochrome c7 TIP120 PF08623.5 KKK12407.1 - 5.7e-62 208.2 0.2 2.9e-61 205.9 0.0 2.4 3 0 0 3 3 3 1 TATA-binding protein interacting (TIP20) HEAT PF02985.17 KKK12407.1 - 2.5e-09 36.4 14.2 0.024 14.7 0.0 8.6 9 0 0 9 9 9 3 HEAT repeat HEAT_2 PF13646.1 KKK12407.1 - 6.1e-09 36.0 13.0 0.26 11.5 0.0 7.2 5 2 3 8 8 8 5 HEAT repeats Arm PF00514.18 KKK12407.1 - 0.00012 21.7 1.6 2.8 7.8 0.0 5.4 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.15 KKK12407.1 - 0.00046 18.6 2.6 5.9 5.0 1.4 5.5 3 1 0 3 3 3 2 Adaptin N terminal region ParcG PF10274.4 KKK12407.1 - 0.045 13.6 0.8 32 4.3 0.0 3.6 2 1 1 3 3 3 0 Parkin co-regulated protein LRR_4 PF12799.2 KKK12408.1 - 9.5e-27 92.1 46.3 1e-06 28.2 1.3 8.9 6 2 1 8 8 8 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KKK12408.1 - 3e-24 84.5 34.1 7e-08 32.1 0.8 6.8 5 1 2 7 7 7 6 Leucine rich repeat LRR_1 PF00560.28 KKK12408.1 - 2.6e-07 29.7 40.9 0.51 10.5 0.1 12.5 11 3 0 11 11 11 4 Leucine Rich Repeat LRR_6 PF13516.1 KKK12408.1 - 4.5e-06 26.1 34.5 0.24 11.5 0.0 10.8 8 3 2 10 10 10 4 Leucine Rich repeat LRR_9 PF14580.1 KKK12408.1 - 0.098 12.2 12.5 0.56 9.7 0.1 3.9 1 1 3 4 4 4 0 Leucine-rich repeat LRR_7 PF13504.1 KKK12408.1 - 0.21 11.9 49.0 4.5 7.8 0.1 12.0 12 1 1 13 13 13 0 Leucine rich repeat WD40 PF00400.27 KKK12409.1 - 4.9e-22 76.9 7.0 1.8e-05 24.3 0.4 5.8 6 0 0 6 6 6 5 WD domain, G-beta repeat SGL PF08450.7 KKK12409.1 - 0.011 15.1 0.0 0.14 11.4 0.0 2.1 1 1 0 2 2 2 0 SMP-30/Gluconolaconase/LRE-like region ATP_bind_1 PF03029.12 KKK12410.1 - 1.1e-73 247.7 0.0 1.3e-73 247.4 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein ArgK PF03308.11 KKK12410.1 - 0.00094 18.0 0.0 0.002 16.9 0.0 1.4 1 0 0 1 1 1 1 ArgK protein AAA_17 PF13207.1 KKK12410.1 - 0.001 19.9 0.2 0.001 19.9 0.1 2.6 2 2 0 2 2 2 1 AAA domain AAA_10 PF12846.2 KKK12410.1 - 0.0016 17.9 0.3 0.021 14.2 0.0 2.1 2 0 0 2 2 2 1 AAA-like domain CbiA PF01656.18 KKK12410.1 - 0.0029 17.0 0.0 0.0063 15.9 0.0 1.6 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MMR_HSR1 PF01926.18 KKK12410.1 - 0.0041 17.0 0.0 0.012 15.6 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_33 PF13671.1 KKK12410.1 - 0.0095 15.8 0.0 0.02 14.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KKK12410.1 - 0.078 12.0 0.4 0.15 11.1 0.0 1.6 2 0 0 2 2 2 0 Zeta toxin MipZ PF09140.6 KKK12410.1 - 0.098 11.7 0.1 0.91 8.5 0.0 2.3 2 2 0 2 2 2 0 ATPase MipZ CDC45 PF02724.9 KKK12410.1 - 0.1 10.6 2.8 0.13 10.2 2.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Bd3614_N PF14442.1 KKK12410.1 - 0.12 12.3 3.9 0.18 11.7 2.7 1.3 1 0 0 1 1 1 0 Bd3614-like deaminase N-terminal AAA_29 PF13555.1 KKK12410.1 - 0.13 11.8 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA_helicase PF00910.17 KKK12410.1 - 0.14 12.3 0.0 0.29 11.3 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_19 PF13245.1 KKK12410.1 - 0.17 11.6 0.0 0.34 10.7 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain ThiF PF00899.16 KKK12411.1 - 1.3e-08 34.7 0.0 3.8e-08 33.2 0.0 1.8 2 0 0 2 2 2 1 ThiF family RuvA_C PF07499.8 KKK12411.1 - 0.092 12.9 0.4 0.47 10.6 0.0 2.4 3 0 0 3 3 3 0 RuvA, C-terminal domain Rib_5-P_isom_A PF06026.9 KKK12412.1 - 1.9e-38 131.4 0.0 3.1e-34 117.7 0.0 2.1 2 0 0 2 2 2 2 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.17 KKK12412.1 - 0.0018 17.9 0.1 1.1 8.9 0.0 2.2 1 1 0 2 2 2 2 DeoR C terminal sensor domain ATP-grasp_2 PF08442.5 KKK12413.1 - 1.6e-08 34.2 0.0 2.3e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain XAP5 PF04921.9 KKK12414.1 - 1.1e-61 208.4 0.4 1.8e-60 204.5 0.0 2.4 3 0 0 3 3 3 1 XAP5, circadian clock regulator FTCD_C PF04961.7 KKK12414.1 - 0.077 12.4 0.9 0.17 11.3 0.6 1.6 1 0 0 1 1 1 0 Formiminotransferase-cyclodeaminase Lge1 PF11488.3 KKK12414.1 - 0.17 12.0 4.1 0.24 11.5 1.6 2.2 2 0 0 2 2 2 0 Transcriptional regulatory protein LGE1 V_ATPase_I PF01496.14 KKK12414.1 - 0.18 9.6 2.5 0.31 8.8 1.7 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family IncA PF04156.9 KKK12414.1 - 0.31 10.6 1.7 0.85 9.1 1.2 1.7 1 0 0 1 1 1 0 IncA protein DUF948 PF06103.6 KKK12414.1 - 0.33 10.8 2.5 0.65 9.9 1.7 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Fib_alpha PF08702.5 KKK12414.1 - 0.41 10.7 6.7 0.83 9.7 4.6 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family RNase_P_Rpp14 PF01900.14 KKK12415.1 - 7e-38 128.8 0.0 9e-38 128.4 0.0 1.1 1 0 0 1 1 1 1 Rpp14/Pop5 family CoA_binding PF02629.14 KKK12416.1 - 3.8e-18 65.7 0.0 1.4e-17 64.0 0.0 2.0 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.14 KKK12416.1 - 3.1e-15 56.1 0.1 5.4e-15 55.3 0.1 1.4 1 0 0 1 1 1 1 CoA-ligase Citrate_synt PF00285.16 KKK12416.1 - 9.7e-15 54.1 0.1 3.2e-12 45.8 0.1 2.9 1 1 1 2 2 2 2 Citrate synthase Succ_CoA_lig PF13607.1 KKK12416.1 - 1.3e-06 28.0 0.0 8.2e-06 25.4 0.0 2.2 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain RRM_1 PF00076.17 KKK12462.1 - 1.2e-16 60.0 0.0 2.1e-16 59.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KKK12462.1 - 7.7e-14 51.4 0.0 1.3e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KKK12462.1 - 1e-05 25.3 0.0 1.6e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Mitofilin PF09731.4 KKK12462.1 - 3 6.3 12.7 4.1 5.9 8.8 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein NARP1 PF12569.3 KKK12462.1 - 9.4 4.8 8.2 13 4.3 5.7 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Sec2p PF06428.6 KKK12463.1 - 6.9e-08 32.2 12.1 6.9e-08 32.2 8.4 2.9 3 0 0 3 3 3 1 GDP/GTP exchange factor Sec2p bZIP_1 PF00170.16 KKK12463.1 - 0.38 10.7 14.6 0.25 11.3 0.4 3.2 2 1 1 3 3 3 0 bZIP transcription factor SPX PF03105.14 KKK12463.1 - 0.77 9.4 12.4 2.4 7.8 8.6 1.9 1 1 0 1 1 1 0 SPX domain DUF444 PF04285.7 KKK12463.1 - 1.1 7.8 12.6 0.12 10.9 4.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF444) Vac_Fusion PF02346.11 KKK12463.1 - 1.5 8.2 7.5 5.4 6.5 1.9 2.7 2 0 0 2 2 2 0 Chordopoxvirus fusion protein PAT1 PF09770.4 KKK12463.1 - 2 6.5 29.3 2.4 6.3 20.3 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 BAF1_ABF1 PF04684.8 KKK12463.1 - 2.5 6.8 10.6 3.2 6.4 7.4 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor MFS_1 PF07690.11 KKK12464.1 - 1.8e-44 151.8 42.9 8.7e-35 120.0 12.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.8 KKK12464.1 - 7e-08 31.0 16.9 3.1e-06 25.6 3.5 2.8 2 2 1 3 3 3 2 Transmembrane secretion effector NAD4L PF06235.6 KKK12464.1 - 0.011 15.4 0.3 0.011 15.4 0.2 2.6 2 0 0 2 2 2 0 NADH dehydrogenase subunit 4L (NAD4L) OATP PF03137.15 KKK12464.1 - 0.012 13.6 5.1 0.015 13.3 1.2 2.5 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family BT1 PF03092.11 KKK12464.1 - 0.24 10.0 14.5 0.017 13.8 0.4 3.1 1 1 2 3 3 3 0 BT1 family PseudoU_synth_2 PF00849.17 KKK12465.1 - 7.4e-26 90.9 0.0 1.2e-25 90.2 0.0 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase FAD_binding_4 PF01565.18 KKK12465.1 - 2.2e-20 72.5 2.7 4.2e-20 71.6 1.8 1.5 1 0 0 1 1 1 1 FAD binding domain S4 PF01479.20 KKK12465.1 - 0.0019 17.5 0.1 0.004 16.5 0.1 1.5 1 0 0 1 1 1 1 S4 domain GFA PF04828.9 KKK12465.1 - 0.096 12.6 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 Glutathione-dependent formaldehyde-activating enzyme Ribosomal_L32e PF01655.13 KKK12466.1 - 6.8e-49 164.5 0.8 1.4e-48 163.5 0.6 1.5 1 0 0 1 1 1 1 Ribosomal protein L32 GFO_IDH_MocA PF01408.17 KKK12466.1 - 2.6e-17 63.4 0.0 7e-17 62.0 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 KKK12466.1 - 0.0031 17.2 0.0 0.0077 16.0 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain 4HBT PF03061.17 KKK12468.1 - 7.9e-14 51.5 0.0 1.1e-13 51.1 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_2 PF13279.1 KKK12468.1 - 2.8e-05 24.5 0.0 3.8e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl-ACP_TE PF01643.12 KKK12468.1 - 0.00094 18.1 0.3 0.0014 17.6 0.2 1.2 1 0 0 1 1 1 1 Acyl-ACP thioesterase ILVD_EDD PF00920.16 KKK12469.1 - 7.9e-106 354.5 0.0 8.9e-106 354.3 0.0 1.0 1 0 0 1 1 1 1 Dehydratase family Peptidase_M29 PF02073.10 KKK12471.1 - 0.066 11.9 0.1 0.07 11.8 0.0 1.0 1 0 0 1 1 1 0 Thermophilic metalloprotease (M29) RuBisCO_small PF00101.15 KKK12471.1 - 0.14 12.0 0.0 0.16 11.8 0.0 1.1 1 0 0 1 1 1 0 Ribulose bisphosphate carboxylase, small chain CH PF00307.26 KKK12493.1 - 4.4e-11 42.7 0.0 7.3e-11 42.0 0.0 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain CDC24 PF06395.6 KKK12493.1 - 0.091 12.8 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 CDC24 Calponin ORMDL PF04061.9 KKK12494.1 - 5.4e-61 204.0 4.3 6.4e-61 203.8 3.0 1.0 1 0 0 1 1 1 1 ORMDL family Trep_Strep PF09605.5 KKK12494.1 - 0.26 10.9 2.4 0.28 10.8 1.0 1.6 1 1 1 2 2 2 0 Hypothetical bacterial integral membrane protein (Trep_Strep) ELL PF10390.4 KKK12495.1 - 0.013 14.7 1.3 0.028 13.6 0.9 1.5 1 0 0 1 1 1 0 RNA polymerase II elongation factor ELL Menin PF05053.8 KKK12495.1 - 0.15 10.2 3.1 0.2 9.7 2.1 1.1 1 0 0 1 1 1 0 Menin DUF819 PF05684.7 KKK12495.1 - 0.17 10.6 0.0 0.28 9.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF819) CDC45 PF02724.9 KKK12495.1 - 0.33 8.9 4.6 0.5 8.3 3.2 1.2 1 0 0 1 1 1 0 CDC45-like protein ArfGap PF01412.13 KKK12497.1 - 1.1e-40 138.0 0.3 1.7e-40 137.4 0.2 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf SelR PF01641.13 KKK12498.1 - 2.4e-51 172.6 0.1 3e-51 172.3 0.1 1.1 1 0 0 1 1 1 1 SelR domain Yippee-Mis18 PF03226.9 KKK12498.1 - 0.19 11.8 2.2 0.57 10.2 1.5 1.8 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DUF2296 PF10058.4 KKK12498.1 - 0.32 10.7 3.6 2.8 7.7 0.1 2.3 2 0 0 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) DNA_RNApol_7kD PF03604.8 KKK12498.1 - 4.8 6.7 7.2 2.6 7.5 0.1 2.6 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit Meiotic_rec114 PF03525.9 KKK12500.1 - 0.0003 19.4 0.1 0.0003 19.4 0.1 1.9 2 1 0 2 2 2 1 Meiotic recombination protein rec114 Zn_clus PF00172.13 KKK12501.1 - 4.6e-10 39.2 8.7 7.5e-10 38.5 6.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.13 KKK12510.1 - 1.1e-10 41.2 9.8 2e-10 40.4 6.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KKK12510.1 - 0.022 13.6 0.0 0.036 12.9 0.0 1.4 1 0 0 1 1 1 0 Fungal specific transcription factor domain FMN_dh PF01070.13 KKK12511.1 - 5.4e-104 347.8 0.6 2.8e-74 250.0 0.2 2.5 1 1 1 2 2 2 2 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 KKK12511.1 - 1.5e-24 85.5 0.0 3.1e-24 84.5 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 KKK12511.1 - 0.0002 20.4 0.0 0.00036 19.5 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 KKK12511.1 - 0.00084 18.3 0.1 0.002 17.0 0.1 1.6 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.10 KKK12511.1 - 0.013 14.6 0.0 0.022 13.9 0.0 1.3 1 0 0 1 1 1 0 Nitronate monooxygenase His_biosynth PF00977.16 KKK12511.1 - 0.032 13.5 0.3 0.75 9.0 0.0 2.2 1 1 1 2 2 2 0 Histidine biosynthesis protein RTX PF02382.10 KKK12511.1 - 0.048 11.9 0.0 0.068 11.4 0.0 1.1 1 0 0 1 1 1 0 RTX N-terminal domain Glyco_hydro_3 PF00933.16 KKK12513.1 - 1.4e-91 306.5 0.0 2.1e-91 306.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KKK12513.1 - 5.6e-49 166.7 0.0 1e-47 162.5 0.0 2.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain DUF572 PF04502.8 KKK12513.1 - 2e-24 86.3 0.0 3.1e-24 85.7 0.0 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF572) Fn3-like PF14310.1 KKK12513.1 - 3.2e-17 62.2 0.4 6.3e-17 61.2 0.3 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain DUF3574 PF12098.3 KKK12513.1 - 0.18 11.4 0.0 0.4 10.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3574) E1-E2_ATPase PF00122.15 KKK12549.1 - 1.1e-58 198.0 1.9 2.3e-58 196.9 1.3 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KKK12549.1 - 1.9e-44 151.3 9.9 1.9e-44 151.3 6.9 2.8 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KKK12549.1 - 3.4e-27 96.2 0.0 1.9e-26 93.8 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KKK12549.1 - 4.9e-20 71.2 0.0 9.9e-20 70.2 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 KKK12549.1 - 7.1e-15 55.6 0.0 1.6e-14 54.5 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KKK12549.1 - 1e-08 34.5 0.2 6.6e-08 31.9 0.0 2.4 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 KKK12549.1 - 0.00089 18.9 1.7 0.0019 17.7 0.4 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase FAD_binding_6 PF00970.19 KKK12561.1 - 4.8e-30 103.6 0.0 7e-30 103.0 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 KKK12561.1 - 2.6e-28 98.7 0.0 4.1e-28 98.1 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 KKK12561.1 - 1.2e-06 28.4 0.0 0.00017 21.5 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 KKK12561.1 - 0.00022 21.1 0.0 0.00038 20.4 0.0 1.4 1 0 0 1 1 1 1 Siderophore-interacting FAD-binding domain DUF4176 PF13780.1 KKK12561.1 - 0.028 14.1 0.0 0.056 13.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4176) SMC_N PF02463.14 KKK12562.1 - 1.3e-72 243.5 0.0 2.1e-72 242.9 0.0 1.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 KKK12562.1 - 3.8e-33 113.9 0.0 2.9e-32 111.1 0.0 2.7 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 KKK12562.1 - 9.6e-19 68.4 2.4 1.9e-09 37.8 0.0 3.7 4 0 0 4 4 4 2 AAA domain AAA_23 PF13476.1 KKK12562.1 - 1.1e-14 55.2 20.6 1.1e-14 55.2 14.3 6.9 2 2 1 3 3 1 1 AAA domain AAA_15 PF13175.1 KKK12562.1 - 8.1e-09 35.0 1.7 8.1e-09 35.0 1.2 3.7 2 2 0 3 3 3 1 AAA ATPase domain AAA_29 PF13555.1 KKK12562.1 - 0.00032 20.1 0.0 0.00076 18.9 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain APG6 PF04111.7 KKK12562.1 - 0.00037 19.6 8.9 0.00037 19.6 6.1 7.3 2 2 3 7 7 7 3 Autophagy protein Apg6 MCPsignal PF00015.16 KKK12562.1 - 0.0022 17.5 3.4 0.0022 17.5 2.3 6.4 6 1 0 6 6 6 1 Methyl-accepting chemotaxis protein (MCP) signalling domain Reo_sigmaC PF04582.7 KKK12562.1 - 0.0094 15.1 32.4 0.2 10.8 1.1 5.4 2 2 2 5 5 5 4 Reovirus sigma C capsid protein FliD_N PF02465.13 KKK12562.1 - 0.011 16.0 1.8 0.011 16.0 1.3 8.0 3 3 5 9 9 8 0 Flagellar hook-associated protein 2 N-terminus FtsK_SpoIIIE PF01580.13 KKK12562.1 - 0.26 10.7 0.0 0.26 10.7 0.0 4.1 4 1 0 4 4 4 0 FtsK/SpoIIIE family ABC_tran PF00005.22 KKK12562.1 - 0.42 10.8 0.0 0.42 10.8 0.0 6.1 3 2 0 3 3 1 0 ABC transporter DUF3605 PF12239.3 KKK12563.1 - 1.7e-54 183.9 0.0 2.1e-54 183.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) KH_1 PF00013.24 KKK12564.1 - 2.1e-27 94.5 1.9 2.1e-07 30.4 0.2 7.2 7 0 0 7 7 7 5 KH domain KH_3 PF13014.1 KKK12564.1 - 4.6e-22 77.2 1.8 0.00059 19.4 0.0 6.4 6 0 0 6 6 6 4 KH domain HATPase_c_5 PF14501.1 KKK12564.1 - 0.17 11.5 0.4 0.39 10.4 0.3 1.6 1 0 0 1 1 1 0 GHKL domain DUF281 PF03436.8 KKK12564.1 - 0.52 10.4 0.1 1.2 9.2 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF281) RIO1 PF01163.17 KKK12565.1 - 2.1e-74 248.9 0.1 2.1e-74 248.9 0.1 1.7 2 0 0 2 2 2 1 RIO1 family APH PF01636.18 KKK12565.1 - 0.0043 16.8 0.0 1.2 8.8 0.0 2.4 1 1 0 2 2 2 2 Phosphotransferase enzyme family APG17 PF04108.7 KKK12566.1 - 2.6e-148 494.2 0.0 3e-148 494.0 0.0 1.0 1 0 0 1 1 1 1 Autophagy protein Apg17 Snapin_Pallidin PF14712.1 KKK12566.1 - 0.073 13.3 1.6 26 5.2 0.0 3.7 4 1 1 5 5 5 0 Snapin/Pallidin HAD_2 PF13419.1 KKK12567.1 - 8.9e-33 113.9 0.1 1.1e-32 113.7 0.1 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KKK12567.1 - 4.8e-06 27.1 0.0 6.7e-06 26.6 0.0 1.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KKK12567.1 - 3.3e-05 23.5 0.0 5.8e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like DUF4437 PF14499.1 KKK12567.1 - 0.0069 15.3 0.0 0.014 14.3 0.0 1.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4437) 5_nucleotid PF05761.9 KKK12567.1 - 0.066 11.7 0.1 0.2 10.1 0.1 1.9 1 1 1 2 2 2 0 5' nucleotidase family Solute_trans_a PF03619.11 KKK12568.1 - 3.6e-98 328.2 1.1 4.8e-98 327.8 0.8 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha WD40 PF00400.27 KKK12571.1 - 8.6e-62 202.9 23.9 9.9e-11 41.1 0.0 8.2 7 1 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.2 KKK12571.1 - 6.7e-15 54.5 0.7 1.8e-14 53.1 0.5 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KKK12571.1 - 5.2e-12 45.1 1.3 2.8e-11 42.7 0.2 2.4 1 1 1 2 2 2 1 F-box domain Nup160 PF11715.3 KKK12571.1 - 2.8e-09 35.6 10.9 0.0029 15.7 0.1 5.7 1 1 3 5 5 5 4 Nucleoporin Nup120/160 PRANC PF09372.5 KKK12571.1 - 0.024 14.6 0.0 0.04 13.8 0.0 1.3 1 0 0 1 1 1 0 PRANC domain Nucleoporin_N PF08801.6 KKK12571.1 - 0.047 12.4 0.4 8.6 4.9 0.1 2.7 1 1 1 2 2 2 0 Nup133 N terminal like Peptidase_A22B PF04258.8 KKK12573.1 - 5e-55 187.0 0.0 3.7e-54 184.2 0.0 1.9 1 1 0 1 1 1 1 Signal peptide peptidase DUF1119 PF06550.6 KKK12573.1 - 2.8e-05 23.4 0.9 2.8e-05 23.4 0.6 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1119) Nucleoplasmin PF03066.10 KKK12573.1 - 0.0008 18.9 3.3 0.46 10.0 0.0 2.3 2 0 0 2 2 2 2 Nucleoplasmin FUSC_2 PF13515.1 KKK12573.1 - 0.059 13.2 0.2 0.059 13.2 0.2 2.6 2 0 0 2 2 2 0 Fusaric acid resistance protein-like FAM176 PF14851.1 KKK12573.1 - 1.3 8.7 0.0 1.3 8.7 0.0 3.6 2 1 2 4 4 4 0 FAM176 family SpoIIIAH PF12685.2 KKK12573.1 - 2.7 7.4 8.7 95 2.3 5.8 2.6 2 1 0 2 2 2 0 SpoIIIAH-like protein Pro-rich PF15240.1 KKK12573.1 - 5.1 7.1 16.4 0.2 11.7 6.8 1.9 2 0 0 2 2 2 0 Proline-rich RNase_PH PF01138.16 KKK12574.1 - 4.4e-17 62.6 1.9 3.5e-15 56.4 1.3 2.4 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 GDI PF00996.13 KKK12575.1 - 7.1e-41 139.9 0.0 9.5e-41 139.5 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor Pro_isomerase PF00160.16 KKK12576.1 - 5e-52 176.2 0.1 5.7e-52 176.0 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF604 PF04646.7 KKK12577.1 - 2e-07 30.4 0.0 3e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF604 Fringe PF02434.11 KKK12577.1 - 1.4e-05 24.4 0.0 3e-05 23.3 0.0 1.4 1 1 0 1 1 1 1 Fringe-like DUF3844 PF12955.2 KKK12628.1 - 4.2e-38 129.5 2.9 6.8e-38 128.9 2.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3844) Ceramidase_alk PF04734.8 KKK12628.1 - 0.094 10.5 2.5 0.13 10.0 1.7 1.1 1 0 0 1 1 1 0 Neutral/alkaline non-lysosomal ceramidase Pro_isomerase PF00160.16 KKK12629.1 - 2.7e-49 167.3 0.6 3.1e-49 167.1 0.4 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD tRNA-synt_2c PF01411.14 KKK12631.1 - 6.8e-216 717.8 0.1 1e-215 717.2 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 KKK12631.1 - 6.7e-17 61.0 0.4 1.6e-16 59.8 0.3 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.14 KKK12631.1 - 0.0016 18.1 0.2 0.0039 16.8 0.1 1.8 1 0 0 1 1 1 1 DHHA1 domain CPSF_A PF03178.10 KKK12632.1 - 1.6e-106 356.0 0.0 8.9e-106 353.5 0.0 2.2 3 0 0 3 3 3 1 CPSF A subunit region Thioredoxin_4 PF13462.1 KKK12633.1 - 1e-06 28.8 0.0 1.4e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin DSBA PF01323.15 KKK12633.1 - 0.078 12.5 1.6 2.5 7.5 0.2 2.3 1 1 0 2 2 2 0 DSBA-like thioredoxin domain TrkA_N PF02254.13 KKK12634.1 - 0.22 11.5 0.0 0.39 10.7 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain zf-RING_2 PF13639.1 KKK12635.1 - 1e-14 54.0 2.9 1.6e-14 53.3 2.0 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 KKK12635.1 - 1.3e-08 34.3 0.9 2.1e-08 33.6 0.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KKK12635.1 - 4.8e-08 32.9 2.5 1.1e-07 31.8 1.7 1.5 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 KKK12635.1 - 9.1e-08 32.0 2.1 1.5e-07 31.3 1.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KKK12635.1 - 4.3e-07 29.5 0.9 6.6e-07 28.9 0.6 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KKK12635.1 - 6.9e-06 25.6 0.4 1e-05 25.0 0.3 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KKK12635.1 - 0.00021 21.0 1.4 0.00066 19.4 1.0 1.8 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.1 KKK12635.1 - 0.0011 18.7 1.7 0.0032 17.3 1.2 1.8 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 KKK12635.1 - 0.0029 17.1 2.8 0.0048 16.4 1.9 1.3 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain PHD PF00628.24 KKK12635.1 - 0.0071 16.0 2.2 0.012 15.3 1.5 1.4 1 0 0 1 1 1 1 PHD-finger RINGv PF12906.2 KKK12635.1 - 0.026 14.5 2.3 0.049 13.6 1.6 1.5 1 0 0 1 1 1 0 RING-variant domain DUF605 PF04652.11 KKK12635.1 - 0.029 13.7 5.2 0.023 14.1 2.7 1.5 1 1 0 1 1 1 0 Vta1 like FANCL_C PF11793.3 KKK12635.1 - 0.2 11.6 3.0 0.6 10.1 2.1 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_UBOX PF13445.1 KKK12635.1 - 0.21 11.3 0.9 0.57 9.9 0.6 1.8 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING-like PF08746.6 KKK12635.1 - 0.22 11.5 2.5 0.36 10.8 1.7 1.4 1 0 0 1 1 1 0 RING-like domain Prok-RING_1 PF14446.1 KKK12635.1 - 0.72 9.6 5.1 5.3 6.8 3.5 2.0 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 Fungal_trans PF04082.13 KKK12636.1 - 2.2e-09 36.5 0.2 5.1e-09 35.3 0.1 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK12636.1 - 4.6e-07 29.6 8.1 8.9e-07 28.7 5.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pinin_SDK_N PF04697.8 KKK12637.1 - 0.0021 18.0 1.9 0.004 17.1 1.3 1.4 1 0 0 1 1 1 1 pinin/SDK conserved region Enkurin PF13864.1 KKK12637.1 - 4.4 7.5 8.3 31 4.8 0.6 3.0 2 1 1 3 3 3 0 Calmodulin-binding HSP70 PF00012.15 KKK12638.1 - 1.1e-230 766.6 8.2 1.1e-230 766.6 5.7 1.9 2 0 0 2 2 2 1 Hsp70 protein RRF PF01765.14 KKK12638.1 - 2e-38 131.4 2.6 7.7e-38 129.5 1.8 2.1 1 0 0 1 1 1 1 Ribosome recycling factor MreB_Mbl PF06723.8 KKK12638.1 - 2.9e-16 58.9 0.1 2.5e-15 55.8 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 KKK12638.1 - 0.00085 18.9 0.0 0.0022 17.6 0.0 1.7 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain MRC1 PF09444.5 KKK12638.1 - 2.7 8.3 10.3 0.1 12.9 1.3 2.4 2 0 0 2 2 2 0 MRC1-like domain CKS PF01111.14 KKK12639.1 - 8.8e-37 124.7 0.3 1.2e-36 124.3 0.2 1.2 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit APC_15aa PF05972.6 KKK12639.1 - 0.11 12.4 0.5 0.34 10.9 0.1 2.1 2 0 0 2 2 2 0 APC 15 residue motif GTP_EFTU PF00009.22 KKK12640.1 - 7.5e-43 146.1 0.0 1.1e-42 145.6 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 KKK12640.1 - 5.1e-27 93.8 0.0 1.5e-26 92.2 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 KKK12640.1 - 4.5e-19 68.0 0.0 1.1e-18 66.8 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 KKK12640.1 - 1.6e-10 40.9 0.0 4.1e-10 39.6 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.1 KKK12640.1 - 4.2e-07 29.7 0.0 1.1e-06 28.4 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.18 KKK12640.1 - 5.6e-05 23.0 0.1 0.00011 22.1 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KKK12640.1 - 0.0026 18.2 0.1 0.0073 16.7 0.1 1.8 1 1 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 KKK12640.1 - 0.049 12.8 0.1 0.35 10.0 0.1 2.3 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Ras PF00071.17 KKK12640.1 - 0.15 11.4 0.0 0.64 9.3 0.0 2.0 1 1 0 1 1 1 0 Ras family Tox-PL PF15644.1 KKK12640.1 - 0.23 12.2 0.0 0.9 10.3 0.0 1.9 2 0 0 2 2 2 0 Papain fold toxin 1 DUF59 PF01883.14 KKK12641.1 - 2.6e-06 27.3 0.1 5.8e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function DUF59 Pheromone PF08015.6 KKK12641.1 - 0.12 13.2 2.5 4.6 8.1 0.0 2.7 3 0 0 3 3 3 0 Fungal mating-type pheromone Atg14 PF10186.4 KKK12642.1 - 1.3e-77 260.7 0.3 1.7e-77 260.3 0.2 1.1 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 ATP_Ca_trans_C PF12424.3 KKK12643.1 - 0.067 13.5 0.3 1.3 9.4 0.0 2.4 1 1 1 2 2 2 0 Plasma membrane calcium transporter ATPase C terminal LMBR1 PF04791.11 KKK12644.1 - 9.5e-09 34.3 2.7 9.5e-09 34.3 1.9 2.3 1 1 1 2 2 2 2 LMBR1-like membrane protein DUF2040 PF09745.4 KKK12644.1 - 0.013 15.3 0.6 0.028 14.2 0.4 1.5 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 55 (DUF2040) Wzy_C PF04932.10 KKK12644.1 - 3.9 7.2 11.3 0.19 11.5 0.9 3.1 2 1 0 2 2 2 0 O-Antigen ligase Thiolase_N PF00108.18 KKK12645.1 - 1.2e-97 326.0 0.0 2.1e-97 325.2 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 KKK12645.1 - 7.3e-45 151.3 3.4 1.1e-44 150.7 1.8 1.7 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 KKK12645.1 - 2.2e-05 24.1 2.7 2.9e-05 23.6 1.1 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 KKK12645.1 - 0.032 13.8 2.1 0.75 9.5 0.0 2.9 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Zip PF02535.17 KKK12646.1 - 5.2e-32 111.1 0.3 6.6e-32 110.7 0.2 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter Ras PF00071.17 KKK12667.1 - 3.5e-52 176.0 0.0 4.1e-52 175.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KKK12667.1 - 5.3e-16 59.1 0.0 8.8e-16 58.4 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KKK12667.1 - 3.6e-06 26.3 0.0 4.9e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Arginase PF00491.16 KKK12668.1 - 2.3e-74 250.1 0.0 3e-74 249.8 0.0 1.1 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.2 KKK12668.1 - 0.0019 18.4 0.1 0.0034 17.5 0.0 1.3 1 0 0 1 1 1 1 UPF0489 domain DUF1349 PF07081.6 KKK12669.1 - 6.1e-26 90.8 0.0 7.7e-26 90.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1349) MFS_1 PF07690.11 KKK12670.1 - 4.1e-23 81.6 39.4 5.7e-13 48.3 13.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KKK12670.1 - 2.2e-06 26.1 21.2 3.7e-06 25.4 14.7 1.3 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) RRM_6 PF14259.1 KKK12671.1 - 0.0027 17.6 0.0 0.0069 16.3 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) CAP59_mtransfer PF11735.3 KKK12672.1 - 9.1e-74 247.7 0.0 1.6e-73 246.9 0.0 1.3 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 Aa_trans PF01490.13 KKK12674.1 - 8.1e-33 113.4 35.5 2e-30 105.5 14.2 2.0 1 1 1 2 2 2 2 Transmembrane amino acid transporter protein Glyco_hydro_18 PF00704.23 KKK12675.1 - 4.4e-39 134.8 0.0 5.6e-39 134.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Pectate_lyase_3 PF12708.2 KKK12676.1 - 1.1e-50 172.8 21.8 6.5e-40 137.6 6.2 4.9 5 0 0 5 5 5 2 Pectate lyase superfamily protein SLT PF01464.15 KKK12676.1 - 0.00034 20.1 0.4 0.00088 18.7 0.1 1.9 2 0 0 2 2 2 1 Transglycosylase SLT domain End_N_terminal PF12218.3 KKK12676.1 - 0.45 10.0 3.8 0.31 10.5 0.0 2.7 3 0 0 3 3 3 0 N terminal extension of bacteriophage endosialidase Sugar_tr PF00083.19 KKK12677.1 - 6.1e-97 325.0 21.9 7e-97 324.8 15.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KKK12677.1 - 8e-34 116.8 44.1 1.1e-28 99.9 17.1 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily ABC_membrane PF00664.18 KKK12677.1 - 0.49 9.7 13.6 1 8.6 2.0 3.8 4 0 0 4 4 4 0 ABC transporter transmembrane region Glyco_hydro_2_N PF02837.13 KKK12678.1 - 1.3e-20 73.6 0.0 2.7e-20 72.5 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.12 KKK12678.1 - 1.4e-09 37.2 0.0 3e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Fungal_trans PF04082.13 KKK12678.1 - 2.1e-09 36.6 0.9 3.6e-09 35.8 0.6 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK12678.1 - 2.5e-08 33.6 8.0 7.4e-08 32.1 5.5 1.9 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_2 PF00703.16 KKK12678.1 - 1e-05 25.9 0.1 6.3e-05 23.3 0.0 2.3 2 1 0 2 2 2 1 Glycosyl hydrolases family 2 MRF_C2 PF13888.1 KKK12678.1 - 0.015 15.0 0.5 0.25 11.1 0.0 2.4 2 0 0 2 2 2 0 Myelin gene regulatory factor C-terminal domain 2 Ctr PF04145.10 KKK12679.1 - 4.5e-41 140.2 3.9 6.6e-41 139.7 2.7 1.3 1 0 0 1 1 1 1 Ctr copper transporter family Aegerolysin PF06355.8 KKK12680.1 - 1.3e-42 144.7 0.0 1.6e-42 144.5 0.0 1.0 1 0 0 1 1 1 1 Aegerolysin Ferric_reduct PF01794.14 KKK12681.1 - 1e-17 64.3 14.0 1e-17 64.3 9.7 2.0 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 KKK12681.1 - 6.5e-16 58.6 0.0 5.2e-15 55.6 0.0 2.0 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 KKK12681.1 - 9.8e-12 44.6 0.0 1.8e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.16 KKK12681.1 - 0.001 19.6 0.0 0.0038 17.7 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Dickkopf_N PF04706.7 KKK12682.1 - 0.0043 17.1 6.0 0.0043 17.1 4.2 2.7 2 1 0 2 2 2 1 Dickkopf N-terminal cysteine-rich region Aldedh PF00171.17 KKK12683.1 - 3e-139 464.3 0.0 3.7e-139 464.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Glyco_hydro_2_C PF02836.12 KKK12684.1 - 6.4e-101 337.1 0.0 8.9e-101 336.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Bgal_small_N PF02929.12 KKK12684.1 - 2.5e-62 210.3 0.0 4.4e-62 209.5 0.0 1.4 1 0 0 1 1 1 1 Beta galactosidase small chain Glyco_hydro_2_N PF02837.13 KKK12684.1 - 3.5e-52 176.3 0.1 6.6e-52 175.4 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.16 KKK12684.1 - 1.6e-16 60.6 0.5 3.5e-16 59.6 0.4 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 MFS_1 PF07690.11 KKK12685.1 - 1.2e-28 99.8 24.8 1.7e-28 99.3 17.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Glyco_hydro_88 PF07470.8 KKK12686.1 - 7.8e-73 245.4 3.6 6.6e-60 202.9 0.1 2.1 1 1 1 2 2 2 2 Glycosyl Hydrolase Family 88 Amidohydro_1 PF01979.15 KKK12686.1 - 5e-56 190.7 0.1 2.8e-55 188.2 0.1 1.9 2 0 0 2 2 2 1 Amidohydrolase family Amidohydro_3 PF07969.6 KKK12686.1 - 2.2e-15 56.7 0.3 2.1e-11 43.6 0.0 3.2 3 0 0 3 3 3 3 Amidohydrolase family Amidohydro_4 PF13147.1 KKK12686.1 - 1.4e-14 54.8 1.0 4.8e-11 43.1 0.0 3.3 3 1 0 3 3 3 2 Amidohydrolase Amidohydro_5 PF13594.1 KKK12686.1 - 1.8e-09 37.2 0.0 7e-09 35.3 0.0 2.1 1 0 0 1 1 1 1 Amidohydrolase A_deaminase PF00962.17 KKK12686.1 - 0.016 14.1 0.0 0.054 12.3 0.0 1.8 1 1 0 1 1 1 0 Adenosine/AMP deaminase DUF367 PF04034.8 KKK12711.1 - 2.1e-29 101.7 0.2 3.2e-29 101.1 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF367) Daxx PF03344.10 KKK12711.1 - 1.5 7.2 17.9 2 6.8 12.4 1.2 1 0 0 1 1 1 0 Daxx Family ALAD PF00490.16 KKK12727.1 - 1.2e-119 399.0 0.0 1.4e-119 398.8 0.0 1.1 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase DUF793 PF05633.6 KKK12727.1 - 0.31 9.7 1.1 0.45 9.2 0.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF793) Mac PF12464.3 KKK12728.1 - 3e-13 49.5 0.0 7.8e-13 48.2 0.0 1.7 1 0 0 1 1 1 1 Maltose acetyltransferase Zn_clus PF00172.13 KKK12728.1 - 9.4e-10 38.2 8.4 1.8e-09 37.3 5.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Hexapep PF00132.19 KKK12728.1 - 1.6e-09 36.8 4.7 0.00011 21.4 0.1 3.7 3 1 1 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 KKK12728.1 - 2.6e-09 36.4 1.8 2.5e-06 26.9 0.0 3.8 4 0 0 4 4 4 2 Hexapeptide repeat of succinyl-transferase DAGK_cat PF00781.19 KKK12729.1 - 5.4e-10 38.8 0.0 1.2e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain zf-C2H2 PF00096.21 KKK12747.1 - 0.0012 19.0 10.7 0.26 11.7 0.8 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KKK12747.1 - 0.0079 16.4 2.6 0.66 10.3 0.1 2.8 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 KKK12747.1 - 0.013 15.7 11.2 2.2 8.8 0.0 4.2 4 0 0 4 4 4 0 C2H2-type zinc finger ATP-synt_C PF00137.16 KKK12752.1 - 0.036 13.9 6.1 0.041 13.7 4.2 1.1 1 0 0 1 1 1 0 ATP synthase subunit C MFS_1 PF07690.11 KKK12752.1 - 5.3 5.6 6.2 5.3 5.6 4.3 1.0 1 0 0 1 1 1 0 Major Facilitator Superfamily SKG6 PF08693.5 KKK12752.1 - 6.2 6.2 5.6 7 6.0 3.9 1.1 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DNA_pol_A_exo1 PF01612.15 KKK12793.1 - 2.5e-22 79.1 0.1 3.4e-22 78.7 0.0 1.1 1 0 0 1 1 1 1 3'-5' exonuclease LSM PF01423.17 KKK12794.1 - 1.5e-14 53.2 0.0 1.7e-14 53.1 0.0 1.1 1 0 0 1 1 1 1 LSM domain PX PF00787.19 KKK12798.1 - 2.3e-13 49.9 0.0 6.3e-13 48.5 0.0 1.7 2 0 0 2 2 2 1 PX domain SNARE PF05739.14 KKK12798.1 - 3.1e-07 29.9 7.5 3.1e-07 29.9 5.2 2.1 2 0 0 2 2 2 1 SNARE domain DGF-1_C PF11040.3 KKK12798.1 - 0.056 13.3 1.0 0.13 12.1 0.1 2.1 2 0 0 2 2 2 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus SIP1 PF04938.7 KKK12799.1 - 4.6e-05 22.8 0.2 0.0015 17.9 0.0 2.6 3 0 0 3 3 3 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) DUF3381 PF11861.3 KKK12799.1 - 4.6 6.7 14.7 0.13 11.8 5.6 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) Pkinase PF00069.20 KKK12800.1 - 1.3e-13 50.7 0.0 3.3e-13 49.3 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.18 KKK12800.1 - 0.0021 17.8 0.0 0.0034 17.1 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 KKK12800.1 - 0.0055 15.6 0.0 0.0084 15.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_Tyr PF07714.12 KKK12800.1 - 0.011 14.8 0.1 0.025 13.6 0.1 1.6 1 1 0 1 1 1 0 Protein tyrosine kinase Kdo PF06293.9 KKK12800.1 - 0.028 13.4 0.0 0.042 12.8 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KKK12800.1 - 0.18 11.1 0.0 0.3 10.4 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Ku PF02735.11 KKK12801.1 - 4.8e-28 97.9 0.0 8.1e-28 97.1 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.10 KKK12801.1 - 1.6e-20 73.5 0.0 2.7e-20 72.7 0.0 1.4 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_PK_bind PF08785.6 KKK12801.1 - 9.5e-18 64.2 0.0 5.2e-17 61.8 0.0 2.2 2 0 0 2 2 2 1 Ku C terminal domain like VWA_2 PF13519.1 KKK12801.1 - 0.0013 18.8 0.0 0.0028 17.7 0.0 1.6 1 1 0 1 1 1 1 von Willebrand factor type A domain tRNA-synt_2 PF00152.15 KKK12802.1 - 9.7e-73 244.8 0.4 1.4e-72 244.2 0.3 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) Hydrolase_6 PF13344.1 KKK12802.1 - 6.8e-24 83.6 0.0 1.9e-23 82.2 0.0 1.8 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KKK12802.1 - 3.4e-10 39.5 0.1 3.1e-09 36.4 0.0 2.6 3 0 0 3 3 3 1 HAD-hyrolase-like tRNA_anti-codon PF01336.20 KKK12802.1 - 2.2e-05 24.2 0.1 4.2e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain HAD_2 PF13419.1 KKK12802.1 - 2.3e-05 24.7 0.2 0.12 12.6 0.0 4.7 4 1 1 5 5 5 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KKK12802.1 - 0.00037 20.9 0.2 0.35 11.2 0.0 3.6 4 0 0 4 4 4 1 haloacid dehalogenase-like hydrolase DUF1570 PF07607.6 KKK12802.1 - 0.11 12.4 0.0 0.37 10.8 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1570) F-box-like PF12937.2 KKK12803.1 - 1.3e-07 31.1 0.1 3.1e-07 30.0 0.1 1.7 1 0 0 1 1 1 1 F-box-like POTRA_1 PF08478.5 KKK12803.1 - 0.01 15.8 0.0 0.022 14.8 0.0 1.6 1 0 0 1 1 1 0 POTRA domain, FtsQ-type F-box PF00646.28 KKK12803.1 - 0.036 13.7 0.0 0.036 13.7 0.0 3.4 4 0 0 4 4 4 0 F-box domain LRR_4 PF12799.2 KKK12803.1 - 0.33 10.6 0.1 0.33 10.6 0.1 3.9 4 1 0 4 4 4 0 Leucine Rich repeats (2 copies) Sugar_tr PF00083.19 KKK12804.1 - 4.9e-69 233.0 22.9 6.7e-69 232.5 15.9 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KKK12804.1 - 4.3e-12 45.4 39.7 4.3e-12 45.4 27.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily KH_1 PF00013.24 KKK12805.1 - 6.2e-40 134.6 7.0 2.3e-15 55.9 0.1 3.3 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 KKK12805.1 - 9.5e-30 101.7 10.8 2.3e-11 43.0 0.9 3.3 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 KKK12805.1 - 2e-10 40.0 6.9 0.0012 18.3 0.1 3.4 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 KKK12805.1 - 1.1e-07 31.3 6.9 0.041 13.5 0.1 3.3 3 0 0 3 3 3 3 KH domain KH_5 PF13184.1 KKK12805.1 - 0.00042 20.0 3.7 0.96 9.3 0.0 3.5 3 0 0 3 3 3 2 NusA-like KH domain dUTPase PF00692.14 KKK12805.1 - 0.0033 16.8 0.0 0.8 9.1 0.0 3.2 3 0 0 3 3 3 1 dUTPase Adaptin_N PF01602.15 KKK12806.1 - 6.3e-112 374.5 0.1 8.2e-112 374.1 0.1 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.5 KKK12806.1 - 1.5e-59 200.1 3.6 1.5e-59 200.1 2.5 2.0 2 0 0 2 2 2 1 Coatomer gamma subunit appendage platform subdomain HEAT_2 PF13646.1 KKK12806.1 - 2e-14 53.5 2.2 0.00011 22.3 0.0 6.4 2 2 3 5 5 5 4 HEAT repeats HEAT_PBS PF03130.11 KKK12806.1 - 0.0027 17.9 0.9 12 6.7 0.0 4.9 4 0 0 4 4 4 1 PBS lyase HEAT-like repeat Cnd1 PF12717.2 KKK12806.1 - 0.0045 16.8 6.6 0.045 13.6 0.3 3.7 3 1 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 DUF1548 PF07579.6 KKK12806.1 - 0.1 12.7 0.6 0.68 10.0 0.1 2.5 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1548) HEAT PF02985.17 KKK12806.1 - 0.11 12.5 8.9 30 5.0 0.1 5.7 6 0 0 6 6 6 0 HEAT repeat dCMP_cyt_deam_1 PF00383.17 KKK12810.1 - 1e-15 57.2 0.3 1.2e-15 56.9 0.2 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.6 KKK12810.1 - 1.3e-08 34.9 0.4 1.6e-08 34.5 0.3 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Peptidase_M42 PF05343.9 KKK12810.1 - 0.043 12.5 0.0 0.046 12.4 0.0 1.1 1 0 0 1 1 1 0 M42 glutamyl aminopeptidase LmjF365940-deam PF14421.1 KKK12810.1 - 0.084 12.2 2.0 0.21 10.9 0.0 2.0 1 1 1 2 2 2 0 A distinct subfamily of CDD/CDA-like deaminases Mito_carr PF00153.22 KKK12811.1 - 9e-68 224.0 0.1 1.7e-23 82.1 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Cgr1 PF03879.9 KKK12812.1 - 2.1e-40 137.2 27.6 2.4e-40 137.0 19.1 1.0 1 0 0 1 1 1 1 Cgr1 family PRP1_N PF06424.7 KKK12812.1 - 0.11 12.8 10.1 0.12 12.7 7.0 1.1 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal SprA-related PF12118.3 KKK12812.1 - 0.24 10.6 10.3 0.27 10.5 7.1 1.1 1 0 0 1 1 1 0 SprA-related family Vfa1 PF08432.5 KKK12812.1 - 0.87 9.5 13.9 1 9.3 9.6 1.0 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Asp-B-Hydro_N PF05279.6 KKK12812.1 - 1.4 8.7 10.8 1.5 8.5 7.5 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DRY_EERY PF09750.4 KKK12812.1 - 2 8.5 8.4 2.5 8.2 5.8 1.3 1 0 0 1 1 1 0 Alternative splicing regulator THOC7 PF05615.8 KKK12812.1 - 3.7 7.8 18.0 5.1 7.3 12.5 1.2 1 0 0 1 1 1 0 Tho complex subunit 7 Hom_end_hint PF05203.11 KKK12812.1 - 4.1 7.0 6.9 4.6 6.9 4.8 1.1 1 0 0 1 1 1 0 Hom_end-associated Hint GAGA_bind PF06217.7 KKK12812.1 - 9.4 6.0 11.8 10 5.9 8.1 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family TMPIT PF07851.8 KKK12812.1 - 9.7 5.1 7.8 11 4.9 5.4 1.0 1 0 0 1 1 1 0 TMPIT-like protein AAA_13 PF13166.1 KKK12813.1 - 0.00027 19.5 0.6 0.00035 19.2 0.4 1.1 1 0 0 1 1 1 1 AAA domain BicD PF09730.4 KKK12813.1 - 0.0031 15.9 0.5 0.0044 15.4 0.3 1.1 1 0 0 1 1 1 1 Microtubule-associated protein Bicaudal-D Spc7 PF08317.6 KKK12813.1 - 0.0066 15.1 0.8 0.009 14.7 0.6 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein GAS PF13851.1 KKK12813.1 - 0.012 14.7 4.2 0.021 14.0 2.9 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Phlebovirus_NSM PF07246.6 KKK12813.1 - 0.051 12.7 0.7 0.087 11.9 0.5 1.3 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M DUF1664 PF07889.7 KKK12813.1 - 0.087 12.6 0.6 0.56 10.0 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) GLTP PF08718.6 KKK12813.1 - 0.1 12.6 0.1 0.21 11.6 0.0 1.6 2 0 0 2 2 2 0 Glycolipid transfer protein (GLTP) HAUS6_N PF14661.1 KKK12813.1 - 0.11 11.8 1.5 0.16 11.3 1.0 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Syntaxin PF00804.20 KKK12813.1 - 0.11 12.7 5.0 0.054 13.6 0.8 2.3 1 1 1 2 2 2 0 Syntaxin IncA PF04156.9 KKK12813.1 - 0.14 11.7 8.6 0.036 13.6 3.3 1.9 2 0 0 2 2 2 0 IncA protein DUF4140 PF13600.1 KKK12813.1 - 0.14 12.5 2.6 0.32 11.4 1.8 1.6 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DUF607 PF04678.8 KKK12813.1 - 0.22 11.4 1.2 0.49 10.3 0.8 1.5 1 1 0 1 1 1 0 Protein of unknown function, DUF607 TBPIP PF07106.8 KKK12813.1 - 0.83 9.1 3.6 1.2 8.6 2.2 1.4 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Matrilin_ccoil PF10393.4 KKK12813.1 - 1.3 8.4 3.5 8.8 5.7 0.0 2.8 2 1 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin Methyltransf_2 PF00891.13 KKK12815.1 - 7.7e-34 116.9 0.0 3.5e-33 114.8 0.0 1.8 1 1 0 1 1 1 1 O-methyltransferase HTH_27 PF13463.1 KKK12815.1 - 0.0041 17.4 0.1 0.013 15.7 0.0 1.8 2 0 0 2 2 2 1 Winged helix DNA-binding domain Dimerisation PF08100.6 KKK12815.1 - 0.034 13.9 0.2 0.16 11.8 0.1 2.1 1 1 0 1 1 1 0 Dimerisation domain Methyltransf_23 PF13489.1 KKK12815.1 - 0.12 12.0 0.1 1.3 8.7 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain FA_hydroxylase PF04116.8 KKK12816.1 - 2.4e-17 63.3 10.1 2.4e-17 63.3 7.0 2.0 3 0 0 3 3 3 1 Fatty acid hydroxylase superfamily PIG-L PF02585.12 KKK12817.1 - 6.9e-17 62.1 0.2 2e-16 60.6 0.1 1.7 1 1 0 1 1 1 1 GlcNAc-PI de-N-acetylase Pyr_redox_3 PF13738.1 KKK12818.1 - 1e-26 94.3 0.0 1.5e-26 93.7 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KKK12818.1 - 3.6e-12 46.1 0.0 6e-10 39.0 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.14 KKK12818.1 - 2.1e-09 36.1 0.0 1.2e-08 33.6 0.0 1.9 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like DAO PF01266.19 KKK12818.1 - 2.2e-07 30.1 0.2 0.00017 20.5 0.0 3.0 3 1 1 4 4 4 2 FAD dependent oxidoreductase K_oxygenase PF13434.1 KKK12818.1 - 3.8e-06 26.0 0.0 0.00059 18.8 0.0 2.4 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.12 KKK12818.1 - 5.5e-06 25.6 0.0 0.00041 19.5 0.0 2.2 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.22 KKK12818.1 - 1.1e-05 25.7 0.0 0.052 13.9 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KKK12818.1 - 5.6e-05 23.1 0.0 0.096 12.5 0.0 2.9 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 KKK12818.1 - 0.0012 18.0 0.0 0.0019 17.3 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.7 KKK12818.1 - 0.0012 17.8 0.0 0.011 14.6 0.0 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 KKK12818.1 - 0.0053 15.6 0.0 0.032 13.0 0.0 2.2 3 0 0 3 3 3 1 FAD binding domain NAD_binding_9 PF13454.1 KKK12818.1 - 0.0057 16.4 0.1 0.64 9.7 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_7 PF13241.1 KKK12818.1 - 0.021 15.0 0.0 0.05 13.8 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding Shikimate_DH PF01488.15 KKK12818.1 - 0.042 13.9 0.0 1.7 8.7 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase ApbA PF02558.11 KKK12818.1 - 0.088 12.2 0.0 0.55 9.6 0.0 2.0 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA HI0933_like PF03486.9 KKK12818.1 - 0.096 11.1 0.0 0.4 9.0 0.0 1.8 2 0 0 2 2 2 0 HI0933-like protein GIDA PF01134.17 KKK12818.1 - 0.2 10.4 0.1 0.43 9.3 0.1 1.5 1 0 0 1 1 1 0 Glucose inhibited division protein A adh_short PF00106.20 KKK12820.1 - 5.5e-23 81.7 0.6 2.2e-22 79.7 0.4 1.9 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KKK12820.1 - 8.2e-07 28.8 1.6 2.5e-05 24.0 1.0 2.3 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KKK12820.1 - 0.00045 20.0 0.0 0.00058 19.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 KKK12820.1 - 0.036 14.0 0.0 0.11 12.4 0.0 1.9 1 1 0 1 1 1 0 NADH(P)-binding Abhydrolase_3 PF07859.8 KKK12821.1 - 9.3e-17 61.3 0.2 1.7e-16 60.4 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 KKK12821.1 - 2.1e-11 43.0 0.0 2.7e-11 42.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 KKK12821.1 - 0.016 14.9 0.1 0.031 14.0 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Fungal_trans PF04082.13 KKK12822.1 - 1.4e-20 73.2 1.5 2.2e-20 72.6 0.4 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK12822.1 - 3.5e-07 30.0 7.1 6.4e-07 29.1 4.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_28 PF00295.12 KKK12823.1 - 2.6e-43 148.2 8.6 1.1e-41 142.9 4.5 2.1 2 0 0 2 2 2 2 Glycosyl hydrolases family 28 YabP PF07873.6 KKK12823.1 - 0.21 11.2 0.9 1.4 8.5 0.0 2.7 3 0 0 3 3 3 0 YabP family Cytochrom_B561 PF03188.11 KKK12824.1 - 2.4e-05 24.1 7.3 2.4e-05 24.1 5.1 2.2 3 0 0 3 3 3 1 Eukaryotic cytochrome b561 DUF2427 PF10348.4 KKK12824.1 - 0.00016 21.1 1.2 0.00016 21.1 0.9 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF2427) DOMON PF03351.12 KKK12824.1 - 0.00025 20.9 0.0 0.00051 19.9 0.0 1.4 1 0 0 1 1 1 1 DOMON domain DUF2306 PF10067.4 KKK12824.1 - 0.037 14.1 5.3 0.076 13.1 0.4 2.6 2 1 0 2 2 2 0 Predicted membrane protein (DUF2306) Ferric_reduct PF01794.14 KKK12824.1 - 0.072 13.1 3.1 0.071 13.2 0.5 2.1 2 0 0 2 2 2 0 Ferric reductase like transmembrane component CopD PF05425.8 KKK12824.1 - 1.5 9.0 9.2 0.23 11.6 0.6 2.8 1 1 1 2 2 2 0 Copper resistance protein D DHquinase_I PF01487.10 KKK12825.1 - 3e-45 154.6 0.0 4.2e-45 154.1 0.0 1.2 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.17 KKK12825.1 - 5.7e-19 68.5 0.2 1.5e-18 67.1 0.0 1.8 2 0 0 2 2 2 1 Shikimate kinase Shikimate_DH PF01488.15 KKK12825.1 - 3.2e-13 49.9 0.1 1.6e-12 47.6 0.1 2.0 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Shikimate_dh_N PF08501.6 KKK12825.1 - 1.5e-12 47.3 0.0 5e-12 45.7 0.0 1.9 2 0 0 2 2 2 1 Shikimate dehydrogenase substrate binding domain F420_oxidored PF03807.12 KKK12825.1 - 0.024 15.0 0.1 0.066 13.6 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Vps23_core PF09454.5 KKK12825.1 - 0.031 13.8 0.1 0.066 12.8 0.1 1.6 1 0 0 1 1 1 0 Vps23 core domain ThiF PF00899.16 KKK12825.1 - 0.1 12.4 0.0 0.3 10.9 0.0 1.8 1 0 0 1 1 1 0 ThiF family ABC2_membrane PF01061.19 KKK12826.1 - 1.5e-73 246.4 55.8 1.5e-40 138.6 18.7 2.7 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 KKK12826.1 - 3e-31 108.5 0.0 4.2e-16 59.4 0.0 2.9 2 1 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 KKK12826.1 - 4.8e-26 90.4 0.1 4.8e-26 90.4 0.1 3.4 4 0 0 4 4 3 2 CDR ABC transporter ABC2_membrane_3 PF12698.2 KKK12826.1 - 3.7e-09 36.0 44.9 1.1e-05 24.6 9.1 2.6 3 0 0 3 3 3 2 ABC-2 family transporter protein AAA_25 PF13481.1 KKK12826.1 - 4.9e-07 29.3 0.0 0.076 12.4 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.1 KKK12826.1 - 0.0002 21.4 0.7 0.0041 17.1 0.1 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.1 KKK12826.1 - 0.00081 18.8 0.2 0.13 11.8 0.1 2.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 KKK12826.1 - 0.003 17.0 0.1 0.66 9.4 0.0 2.6 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_10 PF12846.2 KKK12826.1 - 0.0041 16.6 0.0 3.1 7.1 0.0 2.6 2 0 0 2 2 2 2 AAA-like domain DUF258 PF03193.11 KKK12826.1 - 0.0088 15.2 0.1 0.66 9.1 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 ABC_trans_N PF14510.1 KKK12826.1 - 0.11 12.6 0.0 0.3 11.1 0.0 1.8 1 0 0 1 1 1 0 ABC-transporter extracellular N-terminal AAA_21 PF13304.1 KKK12826.1 - 0.23 11.3 4.0 2.1 8.2 0.0 3.5 4 0 0 4 4 4 0 AAA domain AAA_22 PF13401.1 KKK12826.1 - 0.32 11.1 1.2 22 5.2 0.0 3.1 4 0 0 4 4 4 0 AAA domain DUF1752 PF08550.5 KKK12827.1 - 3.9e-10 39.1 3.0 7.1e-10 38.2 2.1 1.4 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) SUI1 PF01253.17 KKK12828.1 - 1.1e-20 73.2 2.1 2.1e-20 72.3 1.5 1.4 1 0 0 1 1 1 1 Translation initiation factor SUI1 Fungal_trans PF04082.13 KKK12829.1 - 5.8e-19 67.9 0.0 1.4e-18 66.7 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK12829.1 - 7.5e-08 32.1 13.8 1.4e-07 31.3 9.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PBP_sp32 PF07222.7 KKK12829.1 - 0.22 10.6 0.1 0.37 9.9 0.1 1.2 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Fringe PF02434.11 KKK12830.1 - 1.6e-09 37.3 0.2 1.8e-06 27.3 0.0 3.8 3 1 0 3 3 3 1 Fringe-like PAN_1 PF00024.21 KKK12830.1 - 0.0041 16.8 0.3 0.008 15.9 0.2 1.4 1 0 0 1 1 1 1 PAN domain PAN_4 PF14295.1 KKK12830.1 - 0.03 14.0 1.1 0.076 12.7 0.7 1.6 1 0 0 1 1 1 0 PAN domain Glyco_transf_8 PF01501.15 KKK12831.1 - 1.9e-05 24.1 0.4 0.00012 21.4 0.2 2.0 1 1 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.3 KKK12831.1 - 0.0055 16.1 0.0 0.0082 15.5 0.0 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative Chromate_transp PF02417.10 KKK12832.1 - 7.4e-52 175.3 30.9 5.4e-29 100.9 8.1 2.4 3 0 0 3 3 3 2 Chromate transporter MRFAP1 PF15155.1 KKK12832.1 - 0.19 12.0 0.2 0.31 11.3 0.1 1.3 1 0 0 1 1 1 0 MORF4 family-associated protein1 Spt5-NGN PF03439.8 KKK12833.1 - 0.0013 18.4 0.0 0.0021 17.7 0.0 1.4 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section DUF3425 PF11905.3 KKK12834.1 - 1.2e-20 73.8 0.2 2e-20 73.0 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 KKK12834.1 - 0.019 14.8 11.2 0.034 14.0 7.8 1.3 1 0 0 1 1 1 0 bZIP transcription factor Strep_his_triad PF04270.8 KKK12835.1 - 1 9.1 3.6 18 5.1 0.0 2.9 3 0 0 3 3 3 0 Streptococcal histidine triad protein PLA2_B PF01735.13 KKK12836.1 - 1.7e-183 610.2 1.2 2e-183 610.0 0.8 1.0 1 0 0 1 1 1 1 Lysophospholipase catalytic domain Methyltransf_23 PF13489.1 KKK12837.1 - 3.8e-22 78.7 0.0 5.7e-22 78.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KKK12837.1 - 6.4e-11 42.6 0.0 4.9e-10 39.7 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KKK12837.1 - 7.9e-11 42.3 0.0 1.6e-10 41.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KKK12837.1 - 1.4e-10 40.9 0.0 1.9e-09 37.2 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KKK12837.1 - 1.7e-09 38.2 0.0 5.1e-08 33.4 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KKK12837.1 - 0.00021 21.6 0.0 0.00088 19.6 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 KKK12837.1 - 0.001 18.4 0.0 0.002 17.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.13 KKK12837.1 - 0.0023 17.1 0.0 0.036 13.1 0.0 2.5 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.13 KKK12837.1 - 0.0048 16.1 0.0 0.0095 15.1 0.0 1.5 2 0 0 2 2 2 1 O-methyltransferase Methyltransf_26 PF13659.1 KKK12837.1 - 0.0048 16.9 0.0 0.015 15.3 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 KKK12837.1 - 0.0096 15.3 0.0 0.015 14.7 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase PrmA PF06325.8 KKK12837.1 - 0.0097 15.0 0.0 0.015 14.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.12 KKK12837.1 - 0.011 14.8 0.0 0.017 14.2 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase FtsJ PF01728.14 KKK12837.1 - 0.026 14.5 0.0 0.05 13.5 0.0 1.5 1 1 0 1 1 1 0 FtsJ-like methyltransferase Fungal_trans_2 PF11951.3 KKK12838.1 - 0.00037 19.2 2.9 0.0042 15.7 0.4 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain FAD_binding_4 PF01565.18 KKK12839.1 - 5e-14 51.9 0.0 8.2e-14 51.2 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NmrA PF05368.8 KKK12841.1 - 1.1e-35 123.0 0.0 1.3e-35 122.7 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KKK12841.1 - 6.7e-12 45.7 0.1 1e-11 45.1 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 KKK12841.1 - 1.2e-07 30.7 0.0 1.7e-07 30.2 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.13 KKK12841.1 - 0.00015 21.7 0.0 0.00024 21.0 0.0 1.3 1 0 0 1 1 1 1 TrkA-N domain Epimerase PF01370.16 KKK12841.1 - 0.00043 19.7 0.0 0.00061 19.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 KKK12841.1 - 0.0022 17.9 0.0 0.0046 16.9 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase Semialdhyde_dh PF01118.19 KKK12841.1 - 0.017 15.4 0.0 0.029 14.6 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain KR PF08659.5 KKK12841.1 - 0.086 12.5 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 KR domain DapB_N PF01113.15 KKK12841.1 - 0.12 12.2 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus TspO_MBR PF03073.10 KKK12843.1 - 1.6e-42 144.5 10.4 1.6e-42 144.5 7.2 2.6 3 0 0 3 3 3 1 TspO/MBR family MIP PF00230.15 KKK12843.1 - 1.6e-26 93.1 8.9 3.2e-26 92.2 6.2 1.5 1 0 0 1 1 1 1 Major intrinsic protein zf-FCS PF06467.9 KKK12845.1 - 0.072 12.7 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif DUF3435 PF11917.3 KKK12846.1 - 2.9e-26 92.1 6.7 1.5e-18 66.7 2.5 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3435) TT_ORF2 PF02957.10 KKK12846.1 - 0.11 13.2 1.4 0.18 12.5 0.3 1.9 1 1 0 1 1 1 0 TT viral ORF2 APH PF01636.18 KKK12847.1 - 2.7e-14 53.4 0.0 8.9e-14 51.7 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 KKK12847.1 - 8.9e-05 21.6 0.0 0.0011 18.0 0.0 2.3 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF169 PF02596.10 KKK12848.1 - 0.1 11.9 0.0 0.13 11.6 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised ArCR, COG2043 Isochorismatase PF00857.15 KKK12859.1 - 1.2e-36 126.3 0.0 1.1e-35 123.1 0.0 2.3 2 1 0 2 2 2 1 Isochorismatase family FAR1 PF03101.10 KKK12859.1 - 3.6e-06 27.4 0.0 7.4e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 FAR1 DNA-binding domain AFT PF08731.6 KKK12859.1 - 0.088 13.0 0.0 0.15 12.2 0.0 1.3 1 0 0 1 1 1 0 Transcription factor AFT NUDE_C PF04880.8 KKK12860.1 - 3.7e-48 164.0 2.3 3.7e-48 164.0 1.6 4.0 3 1 1 4 4 1 1 NUDE protein, C-terminal conserved region DUF904 PF06005.7 KKK12860.1 - 0.00014 22.0 6.9 0.00014 22.0 4.8 4.1 2 1 2 4 4 4 1 Protein of unknown function (DUF904) BAR_2 PF10455.4 KKK12860.1 - 0.0019 17.1 7.7 0.0035 16.3 5.3 1.4 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking WEMBL PF05701.6 KKK12860.1 - 0.002 16.6 26.1 0.0029 16.1 18.1 1.1 1 0 0 1 1 1 1 Weak chloroplast movement under blue light LPP PF04728.8 KKK12860.1 - 0.054 13.3 0.2 0.4 10.5 0.3 2.3 2 0 0 2 2 2 0 Lipoprotein leucine-zipper Cep57_MT_bd PF06657.8 KKK12860.1 - 0.061 13.2 20.9 0.39 10.6 2.1 3.8 1 1 3 4 4 4 0 Centrosome microtubule-binding domain of Cep57 Myosin_tail_1 PF01576.14 KKK12860.1 - 0.061 11.0 29.3 0.11 10.2 20.3 1.3 1 0 0 1 1 1 0 Myosin tail ApoO PF09769.4 KKK12860.1 - 0.16 11.6 2.9 0.65 9.6 2.0 2.0 1 0 0 1 1 1 0 Apolipoprotein O Chibby PF14645.1 KKK12860.1 - 0.3 10.9 10.8 0.65 9.8 0.3 2.6 1 1 1 2 2 2 0 Chibby family HlyD_2 PF12700.2 KKK12860.1 - 0.34 10.0 10.2 0.51 9.4 7.1 1.3 1 0 0 1 1 1 0 HlyD family secretion protein CENP-F_leu_zip PF10473.4 KKK12860.1 - 0.49 10.2 30.9 0.29 11.0 15.2 3.0 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1664 PF07889.7 KKK12860.1 - 0.51 10.1 10.9 0.063 13.0 3.2 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Tho2 PF11262.3 KKK12860.1 - 0.71 8.8 13.8 1.1 8.2 1.5 2.2 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 Tropomyosin_1 PF12718.2 KKK12860.1 - 0.71 9.7 32.9 1 9.2 15.1 3.4 2 1 1 3 3 3 0 Tropomyosin like DUF745 PF05335.8 KKK12860.1 - 0.79 9.2 11.8 1.6 8.2 8.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF745) DMPK_coil PF08826.5 KKK12860.1 - 1.3 9.0 27.0 0.32 10.9 1.5 4.4 3 1 1 4 4 4 0 DMPK coiled coil domain like V_ATPase_I PF01496.14 KKK12860.1 - 1.4 6.6 20.0 3.4 5.4 9.7 2.1 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family DUF3584 PF12128.3 KKK12860.1 - 1.5 6.0 24.8 2.3 5.4 17.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Filament PF00038.16 KKK12860.1 - 1.9 7.8 27.2 18 4.7 18.9 2.4 1 1 0 1 1 1 0 Intermediate filament protein MAD PF05557.8 KKK12860.1 - 2.1 6.3 33.3 0.075 11.1 12.6 2.5 2 1 1 3 3 3 0 Mitotic checkpoint protein DUF972 PF06156.8 KKK12860.1 - 4.8 7.5 21.8 0.32 11.3 2.0 3.1 2 1 2 4 4 3 0 Protein of unknown function (DUF972) HlyD PF00529.15 KKK12860.1 - 5.3 6.2 14.4 8.8 5.5 10.0 1.3 1 0 0 1 1 1 0 HlyD family secretion protein Peptidase_S46 PF10459.4 KKK12860.1 - 5.8 5.1 10.9 7.9 4.7 7.6 1.1 1 0 0 1 1 1 0 Peptidase S46 ADIP PF11559.3 KKK12860.1 - 5.9 6.7 32.3 1.3 8.9 1.8 3.8 2 1 3 5 5 4 0 Afadin- and alpha -actinin-Binding AAA_13 PF13166.1 KKK12860.1 - 7 4.9 20.4 10 4.4 14.1 1.2 1 0 0 1 1 1 0 AAA domain GAS PF13851.1 KKK12860.1 - 8.2 5.5 29.5 6.7 5.8 14.2 2.7 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Seryl_tRNA_N PF02403.17 KKK12860.1 - 8.8 6.3 25.3 0.36 10.8 7.3 3.2 2 1 2 4 4 3 0 Seryl-tRNA synthetase N-terminal domain IncA PF04156.9 KKK12860.1 - 8.9 5.8 34.7 3.2 7.3 10.4 2.5 2 1 1 3 3 2 0 IncA protein TPR_MLP1_2 PF07926.7 KKK12860.1 - 9.3 6.0 31.8 0.81 9.4 6.3 3.6 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein TBPIP PF07106.8 KKK12860.1 - 9.4 5.7 24.5 1.4 8.4 7.4 3.4 2 1 2 4 4 4 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Fib_alpha PF08702.5 KKK12860.1 - 9.6 6.3 13.8 1.4 9.0 4.9 2.5 2 1 1 3 3 2 0 Fibrinogen alpha/beta chain family ACC_central PF08326.7 KKK12861.1 - 3.1e-262 871.8 0.0 3.9e-262 871.5 0.0 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.17 KKK12861.1 - 1.3e-182 607.6 0.0 2.5e-182 606.6 0.0 1.5 2 0 0 2 2 2 1 Carboxyl transferase domain CPSase_L_D2 PF02786.12 KKK12861.1 - 1.7e-51 174.5 0.0 6.4e-51 172.6 0.0 1.9 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 KKK12861.1 - 5e-24 84.5 0.1 9.4e-24 83.6 0.1 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 KKK12861.1 - 1.2e-22 79.9 0.0 1.1e-19 70.3 0.0 3.6 4 0 0 4 4 4 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.17 KKK12861.1 - 4.6e-16 58.2 0.1 1.2e-15 56.8 0.0 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 KKK12861.1 - 3.7e-09 36.5 0.0 8.9e-09 35.3 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 KKK12861.1 - 3.5e-08 32.5 0.0 0.019 13.7 0.0 3.2 3 0 0 3 3 3 2 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 KKK12861.1 - 0.00034 20.0 0.0 0.00072 18.9 0.0 1.6 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.9 KKK12861.1 - 0.0062 16.4 0.0 0.023 14.5 0.0 2.0 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 KKK12861.1 - 0.12 11.8 0.0 2.1 7.8 0.0 2.3 2 0 0 2 2 2 0 RimK-like ATP-grasp domain Sec7 PF01369.15 KKK12862.1 - 2.3e-40 138.3 0.0 4e-40 137.5 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.1 KKK12862.1 - 2.4e-08 34.1 0.2 5.4e-08 33.0 0.1 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 KKK12862.1 - 0.0004 20.5 0.0 0.0011 19.1 0.0 1.8 1 0 0 1 1 1 1 PH domain Zip PF02535.17 KKK12863.1 - 4.5e-23 81.7 10.5 1.5e-22 80.0 7.3 1.8 1 1 0 1 1 1 1 ZIP Zinc transporter DUF2040 PF09745.4 KKK12864.1 - 1.7e-37 128.0 8.3 1.7e-37 128.0 5.8 3.3 2 1 0 2 2 2 1 Coiled-coil domain-containing protein 55 (DUF2040) Sedlin_N PF04628.8 KKK12865.1 - 2.1e-18 66.4 0.0 2.6e-18 66.1 0.0 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Glyco_hydro_16 PF00722.16 KKK12876.1 - 6.9e-12 45.0 0.3 4.2e-11 42.4 0.1 2.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 Adeno_shaft PF00608.12 KKK12876.1 - 0.012 15.2 0.2 0.027 14.0 0.1 1.6 1 0 0 1 1 1 0 Adenoviral fibre protein (repeat/shaft region) Vps8 PF12816.2 KKK12877.1 - 2.2e-70 235.9 0.0 4.6e-70 234.8 0.0 1.6 1 0 0 1 1 1 1 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.15 KKK12877.1 - 6.3e-06 25.8 0.0 0.22 11.1 0.0 3.1 3 0 0 3 3 3 2 Region in Clathrin and VPS zf-RING_2 PF13639.1 KKK12877.1 - 0.00017 21.3 1.1 0.00048 19.9 0.8 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 KKK12877.1 - 0.0092 15.9 0.7 0.026 14.5 0.5 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Pox_D3 PF04580.8 KKK12877.1 - 0.12 11.5 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 Chordopoxvirinae D3 protein zf-RING_5 PF14634.1 KKK12877.1 - 0.84 9.4 4.2 0.17 11.6 0.3 1.8 2 0 0 2 2 2 0 zinc-RING finger domain Glyco_transf_90 PF05686.7 KKK12878.1 - 4.3e-13 48.7 0.1 4.9e-07 28.7 0.1 3.2 2 1 0 2 2 2 2 Glycosyl transferase family 90 DEAD PF00270.24 KKK12879.1 - 1.8e-17 63.3 0.0 4.5e-17 62.0 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KKK12879.1 - 1e-10 41.2 0.1 2.7e-10 39.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KKK12879.1 - 6.7e-06 26.0 0.0 1.5e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HTH_45 PF14947.1 KKK12879.1 - 6.7e-05 22.6 0.1 0.00029 20.5 0.1 2.0 2 0 0 2 2 2 1 Winged helix-turn-helix AAA_22 PF13401.1 KKK12879.1 - 0.0021 18.1 0.2 0.024 14.8 0.1 2.8 3 1 0 3 3 3 1 AAA domain HHH_5 PF14520.1 KKK12879.1 - 0.0047 17.0 0.0 0.019 15.1 0.0 2.1 1 0 0 1 1 1 1 Helix-hairpin-helix domain DUF4332 PF14229.1 KKK12879.1 - 0.076 12.9 0.1 0.2 11.6 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4332) DUF336 PF03928.9 KKK12879.1 - 0.11 12.2 0.1 3.9 7.2 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF336) eIF-3c_N PF05470.7 KKK12884.1 - 1.3e-172 575.0 26.3 1.3e-172 575.0 18.2 3.1 1 1 1 2 2 2 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.22 KKK12884.1 - 1e-14 54.6 0.9 3.1e-13 49.9 0.1 3.2 2 1 0 2 2 2 1 PCI domain Pox_Ag35 PF03286.9 KKK12884.1 - 3 7.3 17.9 1.4 8.3 5.2 2.4 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Ribosomal_L30_N PF08079.7 KKK12885.1 - 2.1e-26 91.7 16.2 3.6e-26 90.9 11.2 1.4 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.15 KKK12885.1 - 4.4e-16 58.2 3.1 5.7e-16 57.8 1.1 1.9 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e PRK PF00485.13 KKK12886.1 - 0.0012 18.4 0.0 0.0021 17.6 0.0 1.4 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family adh_short PF00106.20 KKK12887.1 - 4.7e-61 205.5 6.1 9.7e-30 103.6 0.1 2.6 2 0 0 2 2 2 2 short chain dehydrogenase MaoC_dehydratas PF01575.14 KKK12887.1 - 5.7e-32 109.6 0.0 1.1e-31 108.7 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain KR PF08659.5 KKK12887.1 - 2.1e-27 95.9 1.1 2.6e-13 50.0 0.3 2.4 2 0 0 2 2 2 2 KR domain THF_DHG_CYH_C PF02882.14 KKK12887.1 - 4.3e-06 25.8 1.4 0.00016 20.7 0.2 2.6 3 0 0 3 3 3 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.16 KKK12887.1 - 0.001 18.5 0.7 1.4 8.3 0.1 2.7 3 0 0 3 3 3 2 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.13 KKK12887.1 - 2.6 7.6 6.8 1.5 8.4 0.6 2.8 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain EAP30 PF04157.11 KKK12888.1 - 2.2e-59 200.3 0.0 2.8e-59 199.9 0.0 1.1 1 0 0 1 1 1 1 EAP30/Vps36 family MarR_2 PF12802.2 KKK12888.1 - 0.0079 15.8 0.4 0.03 13.9 0.0 2.2 3 0 0 3 3 3 1 MarR family Pkinase PF00069.20 KKK12889.1 - 4.6e-51 173.4 0.0 1.2e-50 172.1 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK12889.1 - 1e-22 80.4 0.0 1.8e-22 79.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KKK12889.1 - 0.00038 20.2 0.1 0.00092 19.0 0.1 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 KKK12889.1 - 0.0021 17.4 1.0 0.012 14.9 0.7 2.0 1 1 0 1 1 1 1 RIO1 family DUF4430 PF14478.1 KKK12889.1 - 0.091 12.8 0.0 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4430) SNF2_N PF00176.18 KKK12890.1 - 5.9e-69 232.1 0.0 9.8e-69 231.4 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KKK12890.1 - 2.6e-14 52.8 0.0 7.2e-14 51.4 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KKK12890.1 - 0.025 14.0 0.0 0.3 10.5 0.0 2.4 1 1 0 1 1 1 0 DEAD/DEAH box helicase Atg14 PF10186.4 KKK12890.1 - 0.8 8.5 7.6 1.6 7.5 5.3 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Transketolase_N PF00456.16 KKK12893.1 - 2.3e-07 29.9 0.0 2.5e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Glyco_hydro_3 PF00933.16 KKK12894.1 - 1.5e-91 306.5 0.0 2e-91 306.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KKK12894.1 - 1e-51 175.6 0.2 5.4e-51 173.3 0.1 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KKK12894.1 - 1.9e-20 72.5 0.0 3.4e-20 71.7 0.0 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain Transket_pyr PF02779.19 KKK12895.1 - 2e-05 24.1 0.2 4.9e-05 22.9 0.1 1.8 1 1 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 KKK12895.1 - 4.8e-05 23.2 0.0 0.00011 22.0 0.0 1.7 1 0 0 1 1 1 1 Transketolase, C-terminal domain PITH PF06201.8 KKK12896.1 - 2.1e-42 144.4 0.0 2.9e-42 144.0 0.0 1.2 1 0 0 1 1 1 1 PITH domain Thioredoxin PF00085.15 KKK12896.1 - 3.3e-23 81.3 0.0 6.2e-23 80.4 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 KKK12896.1 - 7.7e-07 29.1 0.0 0.00012 22.1 0.0 2.6 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.1 KKK12896.1 - 7.4e-05 22.9 0.0 0.00023 21.3 0.0 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Redoxin PF08534.5 KKK12896.1 - 0.0014 18.1 1.6 0.18 11.3 0.0 2.6 2 1 1 3 3 3 2 Redoxin AhpC-TSA PF00578.16 KKK12896.1 - 0.0032 17.1 0.2 0.084 12.5 0.1 2.5 1 1 1 2 2 2 2 AhpC/TSA family Thioredoxin_9 PF14595.1 KKK12896.1 - 0.0056 16.2 0.0 0.0099 15.4 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin HyaE PF07449.6 KKK12896.1 - 0.014 15.2 0.0 0.033 14.0 0.0 1.6 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Thioredoxin_7 PF13899.1 KKK12896.1 - 0.019 14.9 0.0 0.042 13.8 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin-like Thioredoxin_3 PF13192.1 KKK12896.1 - 0.045 13.5 0.0 0.1 12.4 0.0 1.7 1 0 0 1 1 1 0 Thioredoxin domain DSBA PF01323.15 KKK12896.1 - 0.055 13.0 0.2 0.13 11.8 0.1 1.7 1 1 1 2 2 2 0 DSBA-like thioredoxin domain DUF836 PF05768.9 KKK12896.1 - 0.12 12.6 0.0 0.33 11.2 0.0 1.8 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) Zn_clus PF00172.13 KKK12929.1 - 7.5e-07 28.9 7.0 1.6e-06 27.9 4.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain KAAG1 PF15354.1 KKK12929.1 - 0.028 14.7 0.2 0.12 12.6 0.0 2.2 3 0 0 3 3 3 0 Kidney-associated antigen 1 PBP_like_2 PF12849.2 KKK12930.1 - 4.2e-08 33.0 2.3 4.2e-08 33.0 1.6 1.8 1 1 1 2 2 2 1 PBP superfamily domain AAL_decarboxy PF03306.8 KKK12930.1 - 0.022 13.8 0.0 1.4 7.9 0.0 2.3 2 0 0 2 2 2 0 Alpha-acetolactate decarboxylase LysR_substrate PF03466.15 KKK12930.1 - 0.052 12.6 0.0 0.088 11.8 0.0 1.3 1 0 0 1 1 1 0 LysR substrate binding domain PHY PF00360.15 KKK12932.1 - 6.7e-28 97.0 0.0 1.4e-27 96.0 0.0 1.4 1 0 0 1 1 1 1 Phytochrome region HATPase_c PF02518.21 KKK12932.1 - 9.9e-19 67.1 0.1 4.2e-18 65.0 0.0 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 KKK12932.1 - 5.9e-18 64.9 0.0 2.6e-17 62.8 0.0 2.2 2 0 0 2 2 2 1 Response regulator receiver domain GAF PF01590.21 KKK12932.1 - 1.6e-12 47.7 0.2 1.7e-11 44.4 0.0 2.7 3 0 0 3 3 3 1 GAF domain HisKA PF00512.20 KKK12932.1 - 6.2e-12 45.3 0.2 2.4e-11 43.4 0.2 2.1 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_2 PF08446.6 KKK12932.1 - 2.4e-05 24.7 0.0 0.00069 20.0 0.0 2.9 2 0 0 2 2 2 1 PAS fold HATPase_c_3 PF13589.1 KKK12932.1 - 0.11 12.1 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase p450 PF00067.17 KKK12933.1 - 4.3e-74 249.6 0.0 5.4e-74 249.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Sugar_tr PF00083.19 KKK12945.1 - 5.1e-41 140.7 18.2 2.4e-29 102.2 2.2 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 KKK12945.1 - 5.2e-25 87.9 23.1 5.2e-25 87.9 16.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily ATG22 PF11700.3 KKK12945.1 - 3e-07 29.3 17.9 0.00023 19.8 2.4 3.0 2 1 0 2 2 2 2 Vacuole effluxer Atg22 like MFS_2 PF13347.1 KKK12945.1 - 4.5e-06 25.3 1.6 4.5e-06 25.3 1.1 3.0 2 1 1 3 3 3 2 MFS/sugar transport protein DUF2516 PF10724.4 KKK12945.1 - 0.027 14.4 1.9 1.3 9.0 0.2 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2516) Pyr_redox_3 PF13738.1 KKK12946.1 - 3.6e-21 76.1 0.0 6.2e-20 72.1 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KKK12946.1 - 1.1e-15 56.8 0.0 7e-13 47.6 0.0 2.1 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 KKK12946.1 - 2.2e-10 40.0 0.1 3.2e-07 29.5 0.0 3.1 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 KKK12946.1 - 1.9e-09 37.7 0.0 1.1e-07 31.9 0.0 2.8 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KKK12946.1 - 5.2e-06 26.3 0.0 4.6e-05 23.3 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KKK12946.1 - 0.0043 17.4 0.0 0.57 10.6 0.0 2.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KKK12946.1 - 0.015 14.2 0.1 0.078 11.8 0.0 2.1 1 1 0 1 1 1 0 Lycopene cyclase protein NAD_binding_9 PF13454.1 KKK12946.1 - 0.017 14.8 0.1 15 5.2 0.0 3.1 3 0 0 3 3 3 0 FAD-NAD(P)-binding DAO PF01266.19 KKK12946.1 - 0.027 13.3 1.5 1.9 7.2 0.0 3.3 4 1 0 4 4 4 0 FAD dependent oxidoreductase 3HCDH_N PF02737.13 KKK12946.1 - 0.18 11.4 0.0 9 5.8 0.0 2.3 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Serglycin PF04360.7 KKK12947.1 - 0.0015 18.2 0.5 0.0029 17.3 0.4 1.5 1 0 0 1 1 1 1 Serglycin DUF1509 PF07420.6 KKK12947.1 - 0.007 15.6 8.5 0.009 15.3 5.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1509) DUF1777 PF08648.7 KKK12947.1 - 0.051 13.3 10.5 0.081 12.6 7.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1777) Corona_nucleoca PF00937.13 KKK12947.1 - 4.3 6.1 12.8 0.05 12.5 3.6 1.5 2 0 0 2 2 2 0 Coronavirus nucleocapsid protein DUF1772 PF08592.6 KKK12948.1 - 1.1e-23 83.5 6.0 1.2e-23 83.3 4.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) TMEM237 PF15383.1 KKK12948.1 - 0.034 13.2 0.0 0.044 12.9 0.0 1.1 1 0 0 1 1 1 0 Transmembrane protein 237 Glyco_transf_22 PF03901.12 KKK12949.1 - 9.2e-79 265.3 15.6 1.2e-78 265.0 10.8 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family CBM_14 PF01607.19 KKK12950.1 - 5.5e-10 39.0 6.0 1e-09 38.1 4.1 1.4 1 1 0 1 1 1 1 Chitin binding Peritrophin-A domain Aminotran_3 PF00202.16 KKK12951.1 - 5.4e-108 360.8 0.0 6.7e-108 360.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 KKK12951.1 - 0.0019 17.1 0.0 0.0036 16.3 0.0 1.4 2 0 0 2 2 2 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 KKK12951.1 - 0.0038 16.4 0.0 0.007 15.5 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Fungal_trans PF04082.13 KKK12952.1 - 2.8e-29 101.7 0.0 4.4e-29 101.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain FAA_hydrolase PF01557.13 KKK12953.1 - 3.1e-49 167.3 0.0 3.8e-49 167.1 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.6 KKK12953.1 - 3.6e-20 71.9 0.0 4.7e-19 68.3 0.0 2.5 3 0 0 3 3 3 1 Fumarylacetoacetase N-terminal Methyltransf_11 PF08241.7 KKK12955.1 - 5.6e-23 81.2 0.0 1.9e-22 79.5 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KKK12955.1 - 1.3e-17 63.8 0.0 2.2e-17 63.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KKK12955.1 - 1.5e-14 54.0 0.0 2.4e-14 53.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KKK12955.1 - 2.4e-13 50.3 0.0 5.7e-13 49.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KKK12955.1 - 3.3e-12 46.7 0.0 9.7e-12 45.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 KKK12955.1 - 5.1e-11 42.1 0.0 7.9e-11 41.5 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.15 KKK12955.1 - 3.4e-10 39.4 0.0 4.8e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_26 PF13659.1 KKK12955.1 - 4.8e-10 39.4 0.1 3.8e-09 36.5 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KKK12955.1 - 7.5e-10 39.3 0.0 1.5e-09 38.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 KKK12955.1 - 8.7e-05 21.9 0.0 0.00015 21.2 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW MTS PF05175.9 KKK12955.1 - 0.00011 21.6 0.0 0.0002 20.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.1 KKK12955.1 - 0.0024 17.5 0.0 0.0049 16.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain FmrO PF07091.6 KKK12955.1 - 0.0041 16.1 0.0 0.019 13.9 0.0 1.9 1 1 1 2 2 2 1 Ribosomal RNA methyltransferase (FmrO) RrnaAD PF00398.15 KKK12955.1 - 0.007 15.4 0.0 0.011 14.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase PCMT PF01135.14 KKK12955.1 - 0.0076 15.7 0.0 0.012 15.1 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_2 PF00891.13 KKK12955.1 - 0.0086 15.2 0.0 0.015 14.5 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase PrmA PF06325.8 KKK12955.1 - 0.0099 15.0 0.0 0.017 14.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_8 PF05148.10 KKK12955.1 - 0.019 14.6 0.0 0.32 10.5 0.0 2.2 1 1 0 1 1 1 0 Hypothetical methyltransferase TehB PF03848.9 KKK12955.1 - 0.023 13.8 0.0 0.039 13.1 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB Usp PF00582.21 KKK12964.1 - 2.9e-22 79.3 0.1 5e-22 78.5 0.0 1.4 1 0 0 1 1 1 1 Universal stress protein family MIF4G PF02854.14 KKK12965.1 - 9e-50 168.9 0.0 9e-50 168.9 0.0 1.8 2 0 0 2 2 2 1 MIF4G domain eIF_4G1 PF12152.3 KKK12965.1 - 1.8e-23 82.2 0.4 7.9e-23 80.1 0.3 2.2 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 Sec3_C PF09763.4 KKK12977.1 - 5.1e-219 728.9 0.3 6.8e-219 728.5 0.2 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.1 KKK12977.1 - 5.6e-30 103.0 0.1 1.2e-29 102.0 0.1 1.6 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Sec3_C_2 PF15278.1 KKK12977.1 - 0.026 14.6 0.3 0.088 12.9 0.2 1.9 1 0 0 1 1 1 0 Sec3 exocyst complex subunit Vps52 PF04129.7 KKK12977.1 - 0.029 12.9 0.3 0.057 11.9 0.2 1.4 1 0 0 1 1 1 0 Vps52 / Sac2 family SRP40_C PF05022.7 KKK12978.1 - 2e-23 82.6 0.5 5.6e-23 81.2 0.3 1.8 1 0 0 1 1 1 1 SRP40, C-terminal domain DUF2653 PF10850.3 KKK12978.1 - 0.19 12.0 0.0 0.3 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2653) F-box-like PF12937.2 KKK12979.1 - 0.00027 20.5 0.1 0.00072 19.2 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KKK12979.1 - 0.0006 19.3 0.1 0.0019 17.7 0.0 1.9 2 0 0 2 2 2 1 F-box domain p450 PF00067.17 KKK12980.1 - 4.2e-50 170.6 0.0 6.8e-50 169.9 0.0 1.2 1 1 0 1 1 1 1 Cytochrome P450 AA_permease_2 PF13520.1 KKK12982.1 - 4.5e-49 167.1 49.6 6.3e-49 166.6 34.4 1.1 1 0 0 1 1 1 1 Amino acid permease CRAL_TRIO PF00650.15 KKK12982.1 - 4.9e-48 162.6 0.1 8.6e-48 161.8 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain AA_permease PF00324.16 KKK12982.1 - 8.4e-24 83.7 47.9 3.8e-23 81.5 33.2 1.8 1 1 0 1 1 1 1 Amino acid permease CRAL_TRIO_2 PF13716.1 KKK12982.1 - 1.9e-12 47.2 0.0 3.5e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.10 KKK12982.1 - 1.1e-09 38.2 0.3 2.7e-09 37.0 0.2 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain DUF2357 PF09823.4 KKK12982.1 - 0.064 12.3 0.1 0.28 10.2 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF2357) Sua5_yciO_yrdC PF01300.13 KKK12983.1 - 2.7e-11 43.0 0.1 3.8e-09 36.0 0.1 2.1 1 1 0 1 1 1 1 Telomere recombination GDPD PF03009.12 KKK12984.1 - 4e-11 42.8 0.0 9.5e-11 41.6 0.0 1.7 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family TauD PF02668.11 KKK12986.1 - 4.8e-54 183.7 0.2 5.8e-54 183.4 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Fungal_trans PF04082.13 KKK12987.1 - 6.1e-21 74.4 1.8 9.6e-21 73.8 1.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 KKK12987.1 - 2.3e-11 43.3 9.4 4.2e-05 23.6 0.4 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KKK12987.1 - 1.2e-09 37.8 9.3 5.2e-05 23.2 2.5 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KKK12987.1 - 2.4e-08 33.8 15.0 1.4e-07 31.4 3.6 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_6 PF13912.1 KKK12987.1 - 0.0085 15.9 4.4 0.044 13.7 0.8 2.5 2 0 0 2 2 2 1 C2H2-type zinc finger zf-FPG_IleRS PF06827.9 KKK12987.1 - 0.11 12.1 2.2 0.82 9.3 1.5 2.3 1 1 0 1 1 1 0 Zinc finger found in FPG and IleRS zf-C2HC_2 PF13913.1 KKK12987.1 - 0.33 10.6 5.3 0.2 11.3 0.7 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2H2_jaz PF12171.3 KKK12987.1 - 0.42 10.8 1.7 2.8 8.2 0.3 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Zn_Tnp_IS1 PF03811.8 KKK12987.1 - 0.96 8.9 4.5 2.2 7.8 3.1 1.6 1 0 0 1 1 1 0 InsA N-terminal domain MFS_1 PF07690.11 KKK12988.1 - 5.7e-42 143.6 30.3 5.7e-42 143.6 21.0 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KKK12988.1 - 9.7e-08 30.6 7.6 1.3e-07 30.2 5.3 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 KKK12988.1 - 4.1e-05 22.3 22.1 0.00022 19.9 15.3 2.3 1 1 0 1 1 1 1 Sugar (and other) transporter MIP PF00230.15 KKK12989.1 - 6.8e-23 81.3 1.4 1e-22 80.7 1.0 1.2 1 0 0 1 1 1 1 Major intrinsic protein Glyco_hydro_28 PF00295.12 KKK12990.1 - 4.2e-111 371.0 18.7 4.9e-111 370.8 13.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 DUF2180 PF09947.4 KKK12990.1 - 0.056 13.2 0.3 0.11 12.2 0.2 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2180) Glyco_hydro_7 PF00840.15 KKK12991.1 - 1.7e-217 722.0 19.4 2.8e-217 721.2 13.4 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 CBM_1 PF00734.13 KKK12991.1 - 1.8e-13 49.8 11.2 1.8e-13 49.8 7.8 4.1 5 0 0 5 5 5 1 Fungal cellulose binding domain Cellulase PF00150.13 KKK12992.1 - 1.7e-55 188.2 0.2 2.8e-55 187.5 0.1 1.4 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.13 KKK12992.1 - 4.8e-14 51.7 10.4 4.8e-14 51.7 7.2 2.4 2 0 0 2 2 2 1 Fungal cellulose binding domain Ammonium_transp PF00909.16 KKK12994.1 - 1.6e-74 250.8 19.0 2.1e-74 250.3 13.2 1.1 1 0 0 1 1 1 1 Ammonium Transporter Family TarH PF02203.10 KKK12994.1 - 0.023 14.5 0.6 0.04 13.7 0.0 1.6 2 0 0 2 2 2 0 Tar ligand binding domain homologue Formyl_trans_N PF00551.14 KKK12995.1 - 4.1e-38 130.7 0.1 5.3e-38 130.3 0.0 1.1 1 0 0 1 1 1 1 Formyl transferase ACT PF01842.20 KKK12995.1 - 8.5e-09 34.7 0.0 2.1e-08 33.4 0.0 1.7 1 0 0 1 1 1 1 ACT domain ACT_6 PF13740.1 KKK12995.1 - 3.2e-07 29.9 0.0 1.2e-06 28.1 0.0 2.0 2 1 1 3 3 3 1 ACT domain DOCK-C2 PF14429.1 KKK12996.1 - 3.8e-33 114.6 0.0 7.2e-33 113.7 0.0 1.5 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins Ded_cyto PF06920.8 KKK12996.1 - 7.1e-15 54.7 0.1 1.8e-14 53.4 0.1 1.7 1 0 0 1 1 1 1 Dedicator of cytokinesis SH3_1 PF00018.23 KKK12996.1 - 5.9e-06 25.5 0.0 1.3e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KKK12996.1 - 0.0003 20.3 0.1 0.0023 17.4 0.0 2.2 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 KKK12996.1 - 0.19 11.2 0.0 0.42 10.1 0.0 1.6 1 0 0 1 1 1 0 Variant SH3 domain CD47 PF04549.9 KKK12996.1 - 0.79 9.7 0.1 1.5 8.7 0.1 1.4 1 0 0 1 1 1 0 CD47 transmembrane region Ribosomal_S8e PF01201.17 KKK12997.1 - 1.2e-45 154.8 2.8 1.6e-45 154.4 2.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S8e DUF2470 PF10615.4 KKK12997.1 - 2.6e-20 72.4 0.0 4.5e-20 71.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) MRP-L27 PF09809.4 KKK13000.1 - 2.2e-15 56.2 0.2 2.6e-15 56.0 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 PARP PF00644.15 KKK13001.1 - 3.1e-12 46.3 0.6 1e-11 44.6 0.1 1.9 1 1 1 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain UQ_con PF00179.21 KKK13001.1 - 1.2e-06 27.9 0.0 4e-06 26.3 0.0 1.9 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KKK13001.1 - 0.027 14.2 0.0 0.058 13.1 0.0 1.7 1 0 0 1 1 1 0 Prokaryotic E2 family B RWD PF05773.17 KKK13001.1 - 0.061 13.2 0.3 0.12 12.2 0.2 1.6 1 1 0 1 1 1 0 RWD domain Glyco_hydro_81 PF03639.8 KKK13002.1 - 3e-204 680.0 7.2 3.8e-204 679.6 5.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 Utp14 PF04615.8 KKK13003.1 - 2.3e-228 760.0 63.3 2.3e-228 760.0 43.9 2.0 1 1 1 2 2 2 1 Utp14 protein SPX PF03105.14 KKK13004.1 - 1.4e-51 175.9 0.1 1.4e-51 175.9 0.1 1.7 2 0 0 2 2 2 1 SPX domain Na_sulph_symp PF00939.14 KKK13004.1 - 1.6e-29 103.0 38.0 2.5e-29 102.5 26.3 1.2 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region Ribosomal_S7 PF00177.16 KKK13004.1 - 8.9e-29 99.9 0.0 2.1e-28 98.7 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e CitMHS PF03600.11 KKK13004.1 - 9.4e-16 57.3 41.4 7.2e-13 47.8 16.3 2.5 1 1 1 2 2 2 2 Citrate transporter Na_Ca_ex PF01699.19 KKK13005.1 - 1.2e-44 151.2 34.9 3.8e-23 81.6 8.7 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein ATP-synt_J PF04911.7 KKK13005.1 - 0.2 11.1 0.3 12 5.4 0.1 2.8 2 0 0 2 2 2 0 ATP synthase j chain DUF912 PF06024.7 KKK13005.1 - 0.4 10.7 1.8 1.6 8.8 0.3 2.5 1 1 1 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Scs3p PF10261.4 KKK13005.1 - 1.1 8.2 8.6 27 3.6 5.5 2.5 1 1 0 1 1 1 0 Inositol phospholipid synthesis and fat-storage-inducing TM DUF4131 PF13567.1 KKK13005.1 - 2.8 7.2 8.3 2.2 7.6 0.0 3.3 2 1 0 3 3 3 0 Domain of unknown function (DUF4131) DUF1129 PF06570.6 KKK13005.1 - 3 7.0 7.9 0.83 8.9 2.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1129) Pyr_redox_3 PF13738.1 KKK13006.1 - 9.7e-28 97.6 0.0 6.2e-27 94.9 0.0 2.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KKK13006.1 - 4.3e-13 48.3 0.0 1.6e-09 36.5 0.0 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 KKK13006.1 - 2e-10 40.1 0.0 2.6e-09 36.4 0.0 2.2 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 KKK13006.1 - 2e-07 31.0 0.0 1.6e-06 28.1 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KKK13006.1 - 8.1e-06 25.6 0.7 0.0054 16.5 0.1 3.1 2 1 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 KKK13006.1 - 0.00025 21.0 0.0 0.0009 19.2 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KKK13006.1 - 0.00071 18.7 0.2 0.0042 16.2 0.0 2.0 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.22 KKK13006.1 - 0.00091 19.5 0.3 0.68 10.3 0.0 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KKK13006.1 - 0.037 12.4 0.0 8.2 4.7 0.0 2.6 3 0 0 3 3 3 0 HI0933-like protein DAO PF01266.19 KKK13006.1 - 0.091 11.6 0.5 4.3 6.1 0.1 2.5 3 0 0 3 3 3 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 KKK13007.1 - 2.5e-27 95.8 0.1 9.2e-16 57.8 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 KKK13007.1 - 4.1e-07 29.2 4.1 0.0003 19.7 1.0 2.5 3 0 0 3 3 3 2 FAD dependent oxidoreductase Amino_oxidase PF01593.19 KKK13007.1 - 6.7e-07 28.7 1.0 0.011 14.8 0.0 2.6 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KKK13007.1 - 3.5e-06 26.9 1.1 3.3e-05 23.8 0.2 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KKK13007.1 - 1.7e-05 23.8 1.0 2.9e-05 23.0 0.7 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 KKK13007.1 - 9.4e-05 22.5 0.4 0.0013 18.8 0.3 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KKK13007.1 - 0.00038 20.8 1.7 0.0079 16.5 0.3 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KKK13007.1 - 0.00049 20.0 0.4 0.00095 19.0 0.2 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 KKK13007.1 - 0.00051 19.6 0.4 0.00086 18.9 0.3 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.7 KKK13007.1 - 0.00098 18.1 0.5 1.1 8.0 0.3 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein Thi4 PF01946.12 KKK13007.1 - 0.0031 16.6 0.2 0.0055 15.8 0.1 1.3 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 KKK13007.1 - 0.0072 14.8 0.3 0.013 14.0 0.2 1.4 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.17 KKK13007.1 - 0.01 14.7 1.4 0.015 14.1 1.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Trp_halogenase PF04820.9 KKK13007.1 - 0.067 11.8 2.3 0.32 9.5 0.2 2.2 2 0 0 2 2 2 0 Tryptophan halogenase NAD_binding_9 PF13454.1 KKK13007.1 - 0.14 11.9 1.4 8.3 6.1 0.0 3.1 3 0 0 3 3 3 0 FAD-NAD(P)-binding DUF3237 PF11578.3 KKK13008.1 - 1.8e-34 118.2 0.0 2.2e-34 117.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) Zn_clus PF00172.13 KKK13009.1 - 3.5e-10 39.6 9.7 3.5e-10 39.6 6.7 1.9 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3439 PF11921.3 KKK13009.1 - 0.083 12.6 11.1 0.18 11.5 7.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Opy2 PF09463.5 KKK13009.1 - 6.3 6.9 11.8 0.57 10.3 2.0 2.9 3 0 0 3 3 3 0 Opy2 protein adh_short PF00106.20 KKK13010.1 - 4.2e-20 72.3 3.9 7.9e-20 71.4 2.7 1.5 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KKK13010.1 - 1.2e-18 67.7 0.2 2.4e-18 66.8 0.2 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KKK13010.1 - 3.6e-07 30.0 1.8 8.3e-07 28.8 1.3 1.5 1 0 0 1 1 1 1 KR domain HHH_5 PF14520.1 KKK13010.1 - 0.035 14.2 0.0 0.079 13.1 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix domain Ldh_1_N PF00056.18 KKK13010.1 - 0.12 12.1 0.1 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain ketoacyl-synt PF00109.21 KKK13011.1 - 1.7e-70 237.4 0.0 4.3e-70 236.0 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 KKK13011.1 - 4.6e-57 193.7 0.0 6.5e-57 193.2 0.0 1.2 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 KKK13011.1 - 1.6e-33 115.0 0.9 4.4e-33 113.6 0.6 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.1 KKK13011.1 - 2.1e-06 27.1 0.2 3.9e-06 26.2 0.1 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Thiolase_N PF00108.18 KKK13011.1 - 4.7e-06 25.7 0.1 9.7e-06 24.7 0.1 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain ACP_syn_III PF08545.5 KKK13011.1 - 0.00042 19.9 0.4 0.001 18.6 0.3 1.6 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III DUF915 PF06028.6 KKK13011.1 - 0.34 9.9 0.0 0.58 9.1 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) DNA_ligase_A_M PF01068.16 KKK13012.1 - 3.2e-51 173.5 0.1 2.6e-48 164.1 0.0 2.3 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 KKK13012.1 - 1.4e-41 142.2 0.0 2.8e-41 141.2 0.0 1.5 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 KKK13012.1 - 6.5e-19 68.1 0.1 4.3e-18 65.5 0.0 2.5 3 0 0 3 3 3 1 ATP dependent DNA ligase C terminal region RINT1_TIP1 PF04437.8 KKK13013.1 - 3.4e-191 636.0 0.0 2.7e-190 633.1 0.0 2.0 2 0 0 2 2 2 1 RINT-1 / TIP-1 family TPR_16 PF13432.1 KKK13013.1 - 0.0044 17.6 4.3 0.018 15.6 3.0 2.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.1 KKK13013.1 - 0.0065 16.0 1.3 0.018 14.7 0.9 1.7 1 0 0 1 1 1 1 TPR repeat Hemerythrin PF01814.18 KKK13013.1 - 0.056 13.5 5.0 0.98 9.5 0.5 3.3 3 0 0 3 3 3 0 Hemerythrin HHE cation binding domain DivIVA PF05103.8 KKK13013.1 - 3.2 7.7 11.8 2.7 8.0 6.6 2.0 2 0 0 2 2 2 0 DivIVA protein TPR_14 PF13428.1 KKK13013.1 - 8.4 7.3 7.7 7.7 7.4 2.0 3.5 3 1 0 3 3 3 0 Tetratricopeptide repeat Metallopep PF12044.3 KKK13014.1 - 2e-174 580.0 0.0 3.3e-174 579.3 0.0 1.3 1 0 0 1 1 1 1 Putative peptidase family Jacalin PF01419.12 KKK13014.1 - 3.6e-05 23.6 0.0 0.0056 16.5 0.0 2.4 1 1 1 2 2 2 2 Jacalin-like lectin domain Reprolysin_5 PF13688.1 KKK13014.1 - 0.025 14.5 0.4 0.054 13.4 0.3 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12 Reprolysin_4 PF13583.1 KKK13014.1 - 0.047 13.2 0.2 0.093 12.2 0.1 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Whi5 PF08528.6 KKK13015.1 - 0.044 13.4 0.1 0.077 12.6 0.1 1.4 1 0 0 1 1 1 0 Whi5 like AAA PF00004.24 KKK13016.1 - 1.2e-18 67.6 0.0 2e-18 66.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KKK13016.1 - 0.0028 17.8 0.5 0.017 15.2 0.3 2.2 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KKK13016.1 - 0.027 14.7 0.1 0.088 13.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 KKK13016.1 - 0.031 14.2 0.0 0.11 12.5 0.0 2.0 1 0 0 1 1 1 0 AAA ATPase domain AAA_17 PF13207.1 KKK13016.1 - 0.048 14.4 0.2 0.37 11.6 0.0 2.6 3 0 0 3 3 3 0 AAA domain Zeta_toxin PF06414.7 KKK13016.1 - 0.093 11.8 0.1 0.19 10.7 0.1 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_5 PF07728.9 KKK13016.1 - 0.097 12.4 0.0 0.23 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) KaiC PF06745.8 KKK13016.1 - 0.31 10.1 1.1 0.72 8.9 0.2 1.9 1 1 1 2 2 2 0 KaiC NACHT PF05729.7 KKK13017.1 - 1.4e-08 34.5 0.0 4.4e-08 32.9 0.0 1.9 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KKK13017.1 - 3.1e-05 24.0 0.0 0.00021 21.3 0.0 2.3 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 KKK13017.1 - 0.0058 16.7 0.6 0.033 14.3 0.0 2.5 3 0 0 3 3 3 1 AAA domain adh_short PF00106.20 KKK13018.1 - 5.7e-15 55.6 0.1 8.8e-15 55.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KKK13018.1 - 0.00044 19.9 0.1 0.00056 19.6 0.0 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 KKK13018.1 - 0.0072 15.2 0.0 0.01 14.7 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein TraL PF07178.6 KKK13019.1 - 0.014 15.4 3.2 2.8 8.0 0.1 3.5 3 0 0 3 3 3 0 TraL protein GMC_oxred_N PF00732.14 KKK13020.1 - 1.4e-51 175.3 0.0 2e-51 174.9 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KKK13020.1 - 3.7e-34 118.0 0.0 6.3e-34 117.3 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 KKK13020.1 - 3e-05 23.1 0.2 0.0011 17.9 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KKK13020.1 - 6.4e-05 21.9 0.0 0.087 11.6 0.1 2.3 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 KKK13020.1 - 0.0023 17.8 0.1 0.0093 15.9 0.1 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 KKK13020.1 - 0.0047 15.9 0.1 0.0079 15.1 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 KKK13020.1 - 0.0078 16.1 0.1 0.031 14.1 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_4 PF01565.18 KKK13020.1 - 0.25 10.8 3.8 5.9 6.3 0.3 3.4 3 0 0 3 3 3 0 FAD binding domain THUMP PF02926.12 KKK13021.1 - 2e-12 47.2 0.8 3.4e-12 46.4 0.1 1.6 2 0 0 2 2 2 1 THUMP domain TPP_enzyme_N PF02776.13 KKK13022.1 - 4.7e-35 120.5 0.0 8.1e-35 119.8 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 KKK13022.1 - 9.5e-27 93.4 0.1 3.3e-26 91.6 0.0 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 KKK13022.1 - 4.5e-15 55.5 0.0 1.5e-14 53.8 0.0 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.15 KKK13022.1 - 0.003 16.3 0.1 0.0053 15.5 0.1 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component Inhibitor_I78 PF11720.3 KKK13022.1 - 0.14 11.9 0.1 3.8 7.3 0.0 3.0 3 0 0 3 3 3 0 Peptidase inhibitor I78 family Pkinase PF00069.20 KKK13023.1 - 9.2e-66 221.6 0.0 1.5e-65 220.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK13023.1 - 5.5e-44 150.1 0.0 8e-44 149.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KKK13023.1 - 3.4e-09 36.0 0.0 3.3e-07 29.5 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.9 KKK13023.1 - 0.021 13.8 0.0 0.037 13.0 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Sec34 PF04136.10 KKK13024.1 - 2.2e-26 92.4 1.5 4.6e-26 91.4 0.6 1.9 2 0 0 2 2 2 1 Sec34-like family NPV_P10 PF05531.7 KKK13024.1 - 0.076 13.2 0.1 4.4 7.6 0.0 2.9 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Exo70 PF03081.10 KKK13024.1 - 0.19 10.4 6.6 0.37 9.5 0.0 3.5 4 0 0 4 4 4 0 Exo70 exocyst complex subunit RCC1 PF00415.13 KKK13025.1 - 4.8e-22 77.9 9.9 4.3e-05 23.6 0.1 7.0 6 1 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 KKK13025.1 - 5.2e-14 51.4 11.2 4.8e-10 38.7 0.0 5.3 6 0 0 6 6 6 2 Regulator of chromosome condensation (RCC1) repeat PUF PF00806.14 KKK13026.1 - 1.9e-16 58.5 0.0 0.028 13.8 0.0 7.7 8 0 0 8 8 8 5 Pumilio-family RNA binding repeat TPR_18 PF13512.1 KKK13026.1 - 0.09 12.7 0.1 3.5 7.6 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Pyridoxal_deC PF00282.14 KKK13027.1 - 5.5e-78 262.0 0.0 6.1e-77 258.5 0.0 2.3 2 1 0 2 2 2 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 KKK13027.1 - 6e-07 28.5 0.0 9.8e-07 27.8 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 KKK13027.1 - 1.6e-05 24.1 0.0 2.2e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase DUF814 PF05670.8 KKK13027.1 - 0.055 13.3 0.0 16 5.4 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF814) SLA_LP_auto_ag PF05889.8 KKK13027.1 - 0.12 10.8 0.0 0.23 9.9 0.0 1.4 1 0 0 1 1 1 0 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) PTR2 PF00854.16 KKK13056.1 - 2.6e-28 98.8 0.6 5.2e-27 94.5 0.4 2.3 1 1 0 1 1 1 1 POT family Pectinesterase PF01095.14 KKK13057.1 - 5.4e-53 179.4 5.4 6.8e-53 179.1 3.8 1.0 1 0 0 1 1 1 1 Pectinesterase Uds1 PF15456.1 KKK13079.1 - 8.2e-45 151.8 5.7 8.2e-45 151.8 4.0 6.7 3 1 4 7 7 7 1 Up-regulated During Septation DUF1843 PF08898.5 KKK13079.1 - 0.015 15.2 1.3 0.015 15.2 0.9 7.4 7 1 2 9 9 9 0 Domain of unknown function (DUF1843) Tropomyosin_1 PF12718.2 KKK13079.1 - 0.84 9.4 90.8 0.028 14.2 3.4 7.3 4 1 3 7 7 7 0 Tropomyosin like Rnk_N PF14760.1 KKK13079.1 - 2.8 8.0 20.8 4.1 7.5 0.1 6.7 6 0 0 6 6 6 0 Rnk N-terminus FlxA PF14282.1 KKK13079.1 - 7.3 6.5 50.5 0.18 11.7 3.3 6.6 4 2 3 7 7 7 0 FlxA-like protein Metallophos PF00149.23 KKK13080.1 - 3.7e-08 33.0 1.6 1.5e-06 27.7 1.1 2.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KKK13080.1 - 0.00046 20.0 0.0 0.0011 18.7 0.0 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain MFS_1 PF07690.11 KKK13082.1 - 2.1e-22 79.3 45.5 3.1e-22 78.7 31.5 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KKK13082.1 - 0.00017 20.3 32.3 0.00069 18.2 22.3 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter ApbA_C PF08546.6 KKK13094.1 - 6e-29 100.5 0.0 1.2e-28 99.6 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 KKK13094.1 - 7.1e-26 90.4 0.1 9.8e-26 90.0 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA AlaDh_PNT_C PF01262.16 KKK13094.1 - 0.082 12.4 0.8 0.17 11.4 0.6 1.5 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ThiF PF00899.16 KKK13094.1 - 0.095 12.5 1.0 0.3 10.9 0.7 1.8 1 0 0 1 1 1 0 ThiF family Fapy_DNA_glyco PF01149.19 KKK13095.1 - 4.2e-26 91.5 0.0 7.9e-26 90.7 0.0 1.5 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain H2TH PF06831.9 KKK13095.1 - 5e-21 74.2 0.0 9e-21 73.4 0.0 1.4 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain YL1 PF05764.8 KKK13095.1 - 0.23 11.0 16.1 0.39 10.2 11.2 1.2 1 0 0 1 1 1 0 YL1 nuclear protein DUF2263 PF10021.4 KKK13096.1 - 8.3e-33 113.4 0.0 1.3e-32 112.8 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) Macro PF01661.16 KKK13096.1 - 0.077 12.9 0.0 0.26 11.2 0.0 1.9 2 0 0 2 2 2 0 Macro domain Ribonuc_L-PSP PF01042.16 KKK13097.1 - 2.2e-33 114.6 0.0 2.4e-33 114.4 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP FMN_dh PF01070.13 KKK13098.1 - 1.8e-124 415.2 1.6 2.1e-124 415.0 1.1 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.20 KKK13098.1 - 1.9e-10 40.1 1.7 8.5e-09 34.7 0.3 2.6 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 KKK13098.1 - 7.9e-08 31.6 1.9 3.4e-05 22.9 0.1 3.0 2 1 1 3 3 3 2 Conserved region in glutamate synthase ThiG PF05690.9 KKK13098.1 - 2.8e-06 26.5 3.2 0.0055 15.8 0.1 3.2 2 1 0 3 3 3 2 Thiazole biosynthesis protein ThiG NMO PF03060.10 KKK13098.1 - 3.9e-06 26.2 0.7 7.1e-06 25.3 0.5 1.4 1 0 0 1 1 1 1 Nitronate monooxygenase PcrB PF01884.12 KKK13098.1 - 3.6e-05 23.1 2.7 0.037 13.2 0.2 2.8 2 1 1 3 3 3 2 PcrB family His_biosynth PF00977.16 KKK13098.1 - 0.00012 21.3 0.7 0.0012 18.1 0.1 2.4 2 1 1 3 3 3 1 Histidine biosynthesis protein DHO_dh PF01180.16 KKK13098.1 - 0.00019 20.5 2.5 0.0029 16.6 0.1 2.2 1 1 1 2 2 2 1 Dihydroorotate dehydrogenase Dus PF01207.12 KKK13098.1 - 0.00029 19.7 0.2 0.037 12.8 0.1 2.2 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) Cid2 PF09774.4 KKK13099.1 - 5.2e-51 172.7 0.0 6.1e-51 172.4 0.0 1.1 1 0 0 1 1 1 1 Caffeine-induced death protein 2 Dymeclin PF09742.4 KKK13099.1 - 0.16 10.0 0.0 0.2 9.7 0.0 1.1 1 0 0 1 1 1 0 Dyggve-Melchior-Clausen syndrome protein CLU PF13236.1 KKK13103.1 - 8.1e-81 270.6 0.0 1.9e-80 269.4 0.0 1.7 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.2 KKK13103.1 - 5.8e-53 179.2 0.1 2.1e-52 177.4 0.0 2.1 2 0 0 2 2 2 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.1 KKK13103.1 - 1.1e-30 105.3 14.0 1.8e-10 40.6 0.0 4.0 1 1 3 4 4 4 4 Tetratricopeptide repeat CLU_N PF15044.1 KKK13103.1 - 1e-26 92.8 0.1 2.9e-26 91.4 0.1 1.8 1 0 0 1 1 1 1 Mitochondrial function, CLU-N-term TPR_10 PF13374.1 KKK13103.1 - 5e-16 58.0 0.0 0.00016 21.5 0.0 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 KKK13103.1 - 6.8e-05 22.4 1.3 0.36 10.8 0.1 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.1 KKK13103.1 - 9.8e-05 21.9 2.9 0.39 10.3 0.0 3.5 2 1 2 4 4 4 3 TPR repeat TPR_16 PF13432.1 KKK13103.1 - 0.00016 22.2 0.0 0.095 13.4 0.0 3.6 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 KKK13103.1 - 0.0036 17.3 2.2 1.2e+02 3.3 0.0 5.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.1 KKK13103.1 - 0.0061 16.2 2.8 0.66 9.8 0.2 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat EnY2 PF10163.4 KKK13103.1 - 0.0085 16.0 0.7 0.087 12.7 0.0 2.8 2 0 0 2 2 2 1 Transcription factor e(y)2 DUF2524 PF10732.4 KKK13103.1 - 0.035 14.2 0.2 0.035 14.2 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2524) NAD_binding_6 PF08030.7 KKK13104.1 - 2.8e-20 72.7 0.0 5.3e-18 65.3 0.0 2.2 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 KKK13104.1 - 3.4e-14 52.5 0.0 1.1e-13 50.9 0.0 1.9 1 1 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 KKK13104.1 - 1.4e-13 51.0 7.7 1.4e-13 51.0 5.3 2.4 2 1 0 2 2 2 1 Ferric reductase like transmembrane component DUF4405 PF14358.1 KKK13104.1 - 0.18 11.9 9.5 9.5 6.4 4.1 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4405) MSA-2c PF12238.3 KKK13105.1 - 0.27 10.8 0.1 0.27 10.8 0.0 2.2 2 0 0 2 2 2 0 Merozoite surface antigen 2c HCO3_cotransp PF00955.16 KKK13106.1 - 1.8e-69 234.7 12.0 9.9e-42 143.2 2.7 2.1 1 1 1 2 2 2 2 HCO3- transporter family GST_N_3 PF13417.1 KKK13107.1 - 1e-12 48.1 0.0 2.3e-12 46.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KKK13107.1 - 3.9e-11 42.7 0.0 9.5e-11 41.5 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain zf-CCHC PF00098.18 KKK13107.1 - 1.5e-10 40.4 12.8 2.6e-05 23.9 0.4 2.8 3 0 0 3 3 3 2 Zinc knuckle GST_C_2 PF13410.1 KKK13107.1 - 2.1e-10 40.3 0.1 4.5e-10 39.2 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 KKK13107.1 - 3.5e-10 39.8 0.0 7.6e-10 38.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KKK13107.1 - 1.1e-09 38.1 0.0 4.1e-09 36.3 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KKK13107.1 - 2.4e-07 31.1 0.1 8.3e-07 29.4 0.0 2.0 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain zf-CCHC_3 PF13917.1 KKK13107.1 - 1.7e-06 27.6 5.2 0.00099 18.7 1.9 2.5 1 1 1 2 2 2 2 Zinc knuckle KH_1 PF00013.24 KKK13107.1 - 0.00048 19.7 0.1 0.0011 18.5 0.1 1.6 1 0 0 1 1 1 1 KH domain zf-CCHC_4 PF14392.1 KKK13107.1 - 0.0021 17.6 6.0 0.41 10.3 0.5 2.5 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_6 PF15288.1 KKK13107.1 - 0.056 13.1 11.8 0.58 9.8 0.4 3.3 3 0 0 3 3 3 0 Zinc knuckle zf-CCHC_2 PF13696.1 KKK13107.1 - 0.086 12.3 0.1 0.086 12.3 0.1 3.3 2 1 1 3 3 2 0 Zinc knuckle DUF1793 PF08760.6 KKK13108.1 - 5.5e-74 247.6 0.3 1.8e-73 245.9 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1793) DEAD PF00270.24 KKK13109.1 - 1.4e-41 141.8 0.0 2.2e-41 141.1 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KKK13109.1 - 1e-25 89.3 0.0 2.4e-25 88.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KKK13109.1 - 0.0013 18.5 0.0 0.0029 17.4 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 KKK13109.1 - 0.013 14.2 0.0 0.023 13.5 0.0 1.4 1 0 0 1 1 1 0 SNF2 family N-terminal domain CTNNBL PF08216.6 KKK13109.1 - 0.1 12.1 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Catenin-beta-like, Arm-motif containing nuclear BSP_II PF05432.6 KKK13110.1 - 0.0097 15.2 9.3 0.0097 15.2 6.4 1.5 2 0 0 2 2 2 1 Bone sialoprotein II (BSP-II) SURF2 PF05477.6 KKK13110.1 - 0.03 13.4 14.1 0.059 12.4 9.8 1.5 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) CDC45 PF02724.9 KKK13110.1 - 1.8 6.5 12.9 3.1 5.7 8.9 1.3 1 0 0 1 1 1 0 CDC45-like protein Terpene_synth_C PF03936.11 KKK13111.1 - 3.4e-13 49.4 5.1 1.8e-12 47.0 3.5 1.9 1 1 0 1 1 1 1 Terpene synthase family, metal binding domain adh_short PF00106.20 KKK13113.1 - 3.8e-13 49.7 0.2 2.2e-12 47.2 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase Epimerase PF01370.16 KKK13113.1 - 0.0019 17.6 0.0 0.0039 16.6 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 KKK13113.1 - 0.0058 16.3 0.0 0.012 15.2 0.0 1.5 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KKK13113.1 - 0.009 15.8 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase ATP-synt_F PF01990.12 KKK13113.1 - 0.04 14.2 0.0 0.078 13.3 0.0 1.4 1 0 0 1 1 1 0 ATP synthase (F/14-kDa) subunit Zn_clus PF00172.13 KKK13114.1 - 8.2e-09 35.2 12.1 1.8e-08 34.1 8.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2205 PF10224.4 KKK13135.1 - 3.9e-31 106.4 3.3 3.9e-31 106.4 2.3 1.6 2 0 0 2 2 2 1 Predicted coiled-coil protein (DUF2205) Macoilin PF09726.4 KKK13135.1 - 0.0031 15.9 4.6 0.0033 15.7 3.2 1.0 1 0 0 1 1 1 1 Transmembrane protein Spectrin PF00435.16 KKK13135.1 - 0.0073 16.5 1.0 0.012 15.9 0.7 1.3 1 0 0 1 1 1 1 Spectrin repeat DUF4140 PF13600.1 KKK13135.1 - 0.024 15.1 1.1 0.044 14.2 0.7 1.6 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) IncA PF04156.9 KKK13135.1 - 0.025 14.1 2.5 0.024 14.2 1.8 1.2 1 0 0 1 1 1 0 IncA protein DUF972 PF06156.8 KKK13135.1 - 0.04 14.2 3.2 0.077 13.3 2.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DivIC PF04977.10 KKK13135.1 - 0.043 13.3 1.4 0.072 12.5 1.0 1.4 1 0 0 1 1 1 0 Septum formation initiator DASH_Dam1 PF08653.5 KKK13135.1 - 0.068 12.9 0.1 0.11 12.2 0.1 1.3 1 0 0 1 1 1 0 DASH complex subunit Dam1 OmpH PF03938.9 KKK13135.1 - 0.1 12.4 4.2 0.13 12.1 2.9 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) HALZ PF02183.13 KKK13135.1 - 0.15 11.8 4.5 1 9.1 0.1 2.3 1 1 1 2 2 2 0 Homeobox associated leucine zipper Spc7 PF08317.6 KKK13135.1 - 0.2 10.2 3.4 0.25 9.9 2.4 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein bZIP_1 PF00170.16 KKK13135.1 - 0.35 10.8 4.8 1.1 9.2 3.4 1.8 1 1 0 1 1 1 0 bZIP transcription factor LCD1 PF09798.4 KKK13135.1 - 1.6 6.6 8.5 0.13 10.1 3.0 1.3 2 0 0 2 2 2 0 DNA damage checkpoint protein HTH_AsnC-type PF13404.1 KKK13135.1 - 5.2 6.6 5.9 9.1 5.9 1.0 2.2 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain Alpha-amylase PF00128.19 KKK13136.1 - 1.1e-51 176.1 0.5 1.3e-51 175.8 0.4 1.0 1 0 0 1 1 1 1 Alpha amylase, catalytic domain RRM_1 PF00076.17 KKK13138.1 - 2.7e-16 58.9 0.0 3.8e-16 58.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KKK13138.1 - 4.2e-13 49.0 0.0 5.9e-13 48.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KKK13138.1 - 6.4e-11 41.9 0.0 8.8e-11 41.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Glyco_hydro_76 PF03663.9 KKK13139.1 - 1.4e-21 77.3 4.8 1.4e-21 77.3 3.3 2.5 2 1 0 2 2 2 1 Glycosyl hydrolase family 76 ubiquitin PF00240.18 KKK13177.1 - 1.1e-07 31.1 0.0 2.2e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family APC10 PF03256.11 KKK13178.1 - 8.2e-40 136.4 0.0 1.5e-30 106.2 0.0 2.1 2 0 0 2 2 2 2 Anaphase-promoting complex, subunit 10 (APC10) Nucleoplasmin PF03066.10 KKK13178.1 - 8.7 5.8 13.2 0.39 10.2 1.2 2.5 2 0 0 2 2 2 0 Nucleoplasmin PS_Dcarbxylase PF02666.10 KKK13179.1 - 7.2e-86 286.6 0.0 1.6e-85 285.4 0.0 1.5 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase PP2C PF00481.16 KKK13180.1 - 5.7e-33 114.3 0.0 7.7e-28 97.5 0.0 2.4 2 0 0 2 2 2 2 Protein phosphatase 2C CDP-OH_P_transf PF01066.16 KKK13180.1 - 1.5e-17 63.7 5.2 4e-17 62.3 3.6 1.7 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase PP2C_2 PF13672.1 KKK13180.1 - 1.6e-05 24.3 0.0 4.4e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 KKK13180.1 - 0.014 15.0 0.0 0.027 14.1 0.0 1.4 1 0 0 1 1 1 0 Stage II sporulation protein E (SpoIIE) Iso_dh PF00180.15 KKK13181.1 - 1.6e-128 428.5 0.0 1.9e-128 428.3 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase LSM PF01423.17 KKK13195.1 - 0.017 14.6 0.1 0.02 14.4 0.1 1.1 1 0 0 1 1 1 0 LSM domain SM-ATX PF14438.1 KKK13195.1 - 0.088 12.7 0.1 0.11 12.3 0.1 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain Homeobox PF00046.24 KKK13196.1 - 8.9e-20 70.0 4.5 2e-19 68.9 3.1 1.7 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KKK13196.1 - 0.0009 18.8 1.0 0.002 17.7 0.7 1.6 1 0 0 1 1 1 1 Homeobox KN domain PGP_phosphatase PF09419.5 KKK13197.1 - 7.1e-58 194.6 0.0 9.6e-58 194.2 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.1 KKK13197.1 - 2.4e-06 27.1 0.0 4.7e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 KKK13197.1 - 0.048 14.0 0.4 1.2 9.4 0.1 2.2 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 KKK13197.1 - 0.071 13.3 0.0 0.19 11.9 0.0 1.7 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Aldedh PF00171.17 KKK13199.1 - 5.7e-157 522.7 0.0 6.6e-157 522.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family GMC_oxred_N PF00732.14 KKK13200.1 - 1e-49 169.3 0.0 1.4e-49 168.8 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KKK13200.1 - 1.4e-40 138.9 0.0 2.1e-40 138.3 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 KKK13200.1 - 1.5e-06 27.3 0.0 0.035 12.9 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 KKK13200.1 - 2.5e-06 26.6 0.4 0.00053 18.9 0.1 2.5 2 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KKK13200.1 - 0.00031 20.7 0.1 0.00086 19.2 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 KKK13200.1 - 0.00059 18.8 0.0 0.00087 18.3 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_oxidored PF12831.2 KKK13200.1 - 0.003 16.7 0.2 0.038 13.0 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KKK13200.1 - 0.0066 16.3 0.0 0.015 15.1 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 KKK13200.1 - 0.023 13.3 0.0 0.033 12.8 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Nitroreductase PF00881.19 KKK13203.1 - 3.6e-14 52.9 0.0 4.4e-14 52.6 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family RTA1 PF04479.8 KKK13204.1 - 7.7e-36 123.6 4.4 9.7e-36 123.3 3.0 1.1 1 0 0 1 1 1 1 RTA1 like protein Zn_clus PF00172.13 KKK13205.1 - 2.4e-10 40.1 11.3 5.2e-10 39.0 7.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KKK13205.1 - 0.00019 20.1 0.0 0.00031 19.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF1422 PF07226.6 KKK13205.1 - 0.16 11.7 0.2 0.31 10.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1422) Pec_lyase_C PF00544.14 KKK13206.1 - 6.9e-20 71.3 6.4 1.5e-19 70.2 4.4 1.6 1 1 0 1 1 1 1 Pectate lyase Beta_helix PF13229.1 KKK13206.1 - 0.00018 21.2 13.6 0.0017 18.1 4.1 2.3 1 1 1 2 2 2 2 Right handed beta helix region Strep_67kDa_ant PF06100.6 KKK13207.1 - 1.4e-97 327.1 0.0 3.1e-96 322.7 0.0 2.0 1 1 0 1 1 1 1 Streptococcal 67 kDa myosin-cross-reactive antigen like family NAD_binding_8 PF13450.1 KKK13207.1 - 7.2e-05 22.7 0.1 0.00015 21.7 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KKK13207.1 - 0.047 12.5 0.0 0.84 8.4 0.0 2.5 3 0 0 3 3 3 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KKK13207.1 - 0.079 12.7 0.1 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding eIF-1a PF01176.14 KKK13207.1 - 0.17 11.3 0.0 0.36 10.2 0.0 1.5 1 0 0 1 1 1 0 Translation initiation factor 1A / IF-1 MFS_1 PF07690.11 KKK13208.1 - 8.2e-37 126.7 53.6 5e-36 124.1 37.0 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily YvrJ PF12841.2 KKK13208.1 - 0.11 11.8 0.3 0.37 10.1 0.0 2.0 2 0 0 2 2 2 0 YvrJ protein family DUF500 PF04366.7 KKK13209.1 - 6.3e-25 87.0 0.0 1.2e-24 86.1 0.0 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF500) Sox_C_TAD PF12067.3 KKK13209.1 - 0.17 12.0 3.7 0.3 11.2 2.6 1.3 1 0 0 1 1 1 0 Sox C-terminal transactivation domain DUF3431 PF11913.3 KKK13210.1 - 2.7e-75 252.6 0.0 3.3e-75 252.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) Fungal_trans_2 PF11951.3 KKK13211.1 - 2.9e-13 49.1 0.1 1.4e-12 46.9 0.1 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK13211.1 - 2.2e-06 27.4 12.9 2.2e-06 27.4 8.9 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SIMPL PF04402.9 KKK13212.1 - 7.8e-25 87.9 0.0 1e-24 87.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF541) Pkinase PF00069.20 KKK13213.1 - 4.1e-26 91.6 0.0 5.8e-26 91.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK13213.1 - 1.5e-06 27.4 0.2 3.6e-05 22.9 0.1 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Metallophos PF00149.23 KKK13214.1 - 1.1e-16 60.8 0.1 2.8e-16 59.5 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.1 KKK13214.1 - 5.7e-16 58.3 0.0 1.2e-15 57.3 0.0 1.6 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C PhoD PF09423.5 KKK13214.1 - 3.5e-05 22.5 0.1 6.4e-05 21.7 0.1 1.4 1 0 0 1 1 1 1 PhoD-like phosphatase fn3 PF00041.16 KKK13214.1 - 0.0043 17.1 2.0 0.0093 16.0 1.4 1.5 1 0 0 1 1 1 1 Fibronectin type III domain Metallophos_2 PF12850.2 KKK13214.1 - 0.0097 15.7 0.2 0.026 14.3 0.1 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Cupin_2 PF07883.6 KKK13214.1 - 0.068 12.6 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 Cupin domain PARP PF00644.15 KKK13215.1 - 2.4e-44 151.2 0.0 1.1e-43 149.0 0.0 1.9 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.9 KKK13215.1 - 3.2e-33 114.2 0.2 5.5e-33 113.4 0.1 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain BRCT PF00533.21 KKK13215.1 - 2.3e-08 34.0 0.0 5.6e-08 32.8 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain WGR PF05406.10 KKK13215.1 - 3.4e-08 33.3 1.1 6.9e-08 32.3 0.7 1.5 1 0 0 1 1 1 1 WGR domain PTCB-BRCT PF12738.2 KKK13215.1 - 7.4e-06 25.7 0.2 1.5e-05 24.7 0.1 1.6 1 0 0 1 1 1 1 twin BRCT domain Glyco_hydro_3 PF00933.16 KKK13216.1 - 1.6e-73 247.2 0.0 2.3e-73 246.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KKK13216.1 - 2.8e-47 161.1 0.0 4.2e-47 160.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KKK13216.1 - 5e-11 42.3 0.0 9.6e-11 41.4 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Zn_clus PF00172.13 KKK13217.1 - 1.8e-08 34.1 11.8 3.8e-08 33.0 8.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KKK13217.1 - 2e-05 23.5 1.2 3.7e-05 22.7 0.9 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pyridoxal_deC PF00282.14 KKK13218.1 - 1.5e-106 355.9 0.0 1.9e-106 355.6 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.16 KKK13218.1 - 0.0056 15.8 0.0 0.0086 15.2 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase AMP-binding PF00501.23 KKK13219.1 - 2.9e-31 108.3 0.0 5.1e-31 107.4 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 KKK13219.1 - 4.7e-28 97.7 0.0 7.4e-28 97.1 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 KKK13219.1 - 7.2e-14 51.7 0.0 1.3e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 KKK13219.1 - 0.0014 18.3 0.0 0.019 14.6 0.1 2.6 2 1 0 2 2 2 1 KR domain PP-binding PF00550.20 KKK13219.1 - 0.0014 18.8 0.0 0.0036 17.5 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site RmlD_sub_bind PF04321.12 KKK13219.1 - 0.0034 16.3 0.0 0.055 12.3 0.0 2.2 2 0 0 2 2 2 1 RmlD substrate binding domain adh_short PF00106.20 KKK13219.1 - 0.0042 17.0 0.1 0.009 15.9 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.8 KKK13219.1 - 0.034 13.4 0.0 0.055 12.7 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family DXP_reductoisom PF02670.11 KKK13219.1 - 0.17 12.4 0.0 0.37 11.3 0.0 1.6 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Semialdhyde_dh PF01118.19 KKK13219.1 - 0.19 12.0 0.0 0.35 11.1 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.10 KKK13219.1 - 0.3 9.9 0.0 0.53 9.1 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Methyltransf_2 PF00891.13 KKK13220.1 - 8e-06 25.2 0.1 2.3e-05 23.7 0.0 1.7 1 1 0 1 1 1 1 O-methyltransferase Dimerisation PF08100.6 KKK13220.1 - 0.00036 20.3 0.8 0.001 18.8 0.5 1.8 1 0 0 1 1 1 1 Dimerisation domain NAD4L PF06235.6 KKK13221.1 - 2.2 8.0 9.4 0.65 9.8 0.1 2.9 2 1 0 3 3 3 0 NADH dehydrogenase subunit 4L (NAD4L) FAD_binding_2 PF00890.19 KKK13222.1 - 5.6e-63 213.2 0.7 6.6e-63 212.9 0.5 1.0 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 KKK13222.1 - 5.4e-10 38.7 0.1 2.8e-09 36.3 0.1 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KKK13222.1 - 5.6e-08 32.9 0.0 1.5e-05 24.9 0.0 2.8 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KKK13222.1 - 9.9e-08 31.9 0.1 6.1e-07 29.3 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 KKK13222.1 - 6.9e-07 29.5 0.0 7.1e-06 26.2 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KKK13222.1 - 1.2e-06 27.3 1.2 0.0036 15.8 0.1 3.1 3 0 0 3 3 3 2 HI0933-like protein GIDA PF01134.17 KKK13222.1 - 6.8e-06 25.1 3.3 0.0012 17.8 0.2 2.9 3 0 0 3 3 3 2 Glucose inhibited division protein A Thi4 PF01946.12 KKK13222.1 - 0.0001 21.4 0.4 0.00096 18.3 0.1 2.2 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.14 KKK13222.1 - 0.00013 21.1 0.5 0.00025 20.1 0.1 1.6 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.2 KKK13222.1 - 0.00045 19.4 0.0 0.0014 17.7 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KKK13222.1 - 0.0087 16.4 0.4 0.036 14.4 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 KKK13222.1 - 0.013 15.1 0.0 0.023 14.3 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lycopene_cycl PF05834.7 KKK13222.1 - 0.016 14.1 0.4 0.044 12.6 0.2 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_7 PF13241.1 KKK13222.1 - 0.028 14.6 0.0 0.056 13.6 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding AlaDh_PNT_C PF01262.16 KKK13222.1 - 0.08 12.5 0.1 0.15 11.5 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain MFS_1 PF07690.11 KKK13223.1 - 3.5e-51 173.9 46.2 3.5e-51 173.9 32.0 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KKK13223.1 - 3.7e-21 74.9 22.6 5.5e-21 74.3 15.6 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 KKK13223.1 - 8.2e-16 57.6 6.6 8.2e-16 57.6 4.5 2.7 2 1 0 2 2 2 1 Sugar (and other) transporter DUF500 PF04366.7 KKK13223.1 - 0.049 13.0 0.0 0.093 12.1 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF500) DUF543 PF04418.7 KKK13223.1 - 3.1 7.8 8.4 14 5.7 0.1 4.6 3 1 1 4 4 4 0 Domain of unknown function (DUF543) Arrestin_C PF02752.17 KKK13224.1 - 5.2e-10 39.5 0.2 1.2e-09 38.3 0.0 1.6 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Fungal_trans PF04082.13 KKK13225.1 - 2.5e-13 49.4 0.0 4.7e-13 48.6 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK13225.1 - 0.11 12.3 6.7 0.23 11.3 4.7 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Ank_2 PF12796.2 KKK13226.1 - 1.4e-54 182.3 1.2 5e-16 58.8 0.0 4.0 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 KKK13226.1 - 2e-41 137.7 6.3 5.6e-09 35.3 0.0 7.3 7 0 0 7 7 7 7 Ankyrin repeat Ank_4 PF13637.1 KKK13226.1 - 1.7e-39 133.4 2.2 7.9e-13 48.5 0.0 4.8 4 1 1 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 KKK13226.1 - 6.4e-34 115.2 5.5 2.8e-08 33.7 0.0 6.0 2 2 4 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 KKK13226.1 - 1.5e-30 102.1 0.9 3.4e-07 29.8 0.0 7.3 7 0 0 7 7 7 4 Ankyrin repeat F-box-like PF12937.2 KKK13226.1 - 0.07 12.8 0.6 0.14 11.8 0.4 1.5 1 0 0 1 1 1 0 F-box-like FCD PF07729.7 KKK13226.1 - 0.13 12.5 2.4 3.1 8.1 0.1 2.4 2 1 0 2 2 2 0 FCD domain FA_hydroxylase PF04116.8 KKK13227.1 - 5.1e-13 49.4 16.2 5.1e-13 49.4 11.2 2.2 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily bZIP_1 PF00170.16 KKK13228.1 - 4.7e-06 26.4 0.6 8.4e-06 25.6 0.4 1.4 1 0 0 1 1 1 1 bZIP transcription factor Glutaredoxin2_C PF04399.8 KKK13228.1 - 0.11 12.0 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain ATG16 PF08614.6 KKK13228.1 - 0.15 11.9 0.8 0.24 11.2 0.6 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Epimerase PF01370.16 KKK13229.1 - 1.2e-15 57.6 0.7 8.4e-15 54.8 0.5 2.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KKK13229.1 - 2.7e-10 39.4 0.0 3.8e-10 38.9 0.0 1.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 KKK13229.1 - 2.9e-09 37.1 0.7 7.8e-09 35.7 0.4 1.8 2 0 0 2 2 2 1 NADH(P)-binding NAD_binding_4 PF07993.7 KKK13229.1 - 2.4e-08 33.2 0.0 5.1e-07 28.8 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.8 KKK13229.1 - 9.8e-05 21.7 0.0 0.00019 20.7 0.0 1.5 2 0 0 2 2 2 1 NmrA-like family Polysacc_synt_2 PF02719.10 KKK13229.1 - 0.0001 21.3 0.0 0.00016 20.7 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.20 KKK13229.1 - 0.002 18.0 1.0 0.0063 16.4 0.7 1.8 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KKK13229.1 - 0.13 11.8 0.6 0.55 9.8 0.4 2.0 1 1 0 1 1 1 0 KR domain MFS_1 PF07690.11 KKK13230.1 - 9.7e-33 113.3 47.9 1.5e-21 76.5 18.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KKK13230.1 - 4.7e-06 25.4 44.2 0.00019 20.1 12.0 3.1 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.2 KKK13230.1 - 4.9e-05 23.0 9.2 0.0019 17.9 3.7 3.6 3 0 0 3 3 3 1 MFS_1 like family ADH_zinc_N_2 PF13602.1 KKK13231.1 - 2.2e-15 57.6 0.1 4.8e-15 56.5 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 KKK13231.1 - 1.6e-12 47.1 0.2 2.7e-12 46.3 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KKK13231.1 - 2.8e-05 23.8 0.0 0.00015 21.4 0.0 2.0 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain NAD_binding_10 PF13460.1 KKK13231.1 - 0.001 19.1 0.3 0.0022 17.9 0.1 1.7 2 0 0 2 2 2 1 NADH(P)-binding RmlD_sub_bind PF04321.12 KKK13231.1 - 0.031 13.1 0.0 0.066 12.0 0.0 1.5 1 0 0 1 1 1 0 RmlD substrate binding domain AvrE PF11725.3 KKK13232.1 - 0.067 10.2 5.7 0.093 9.7 3.9 1.0 1 0 0 1 1 1 0 Pathogenicity factor KIAA1328 PF15369.1 KKK13232.1 - 7.5 6.2 6.8 11 5.7 4.7 1.1 1 0 0 1 1 1 0 Uncharacterised protein KIAA1328 Glyco_hydro_61 PF03443.9 KKK13233.1 - 3.9e-45 154.3 0.0 5.2e-45 153.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Fungal_trans PF04082.13 KKK13234.1 - 2.1e-12 46.4 0.0 3e-12 45.9 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_43 PF04616.9 KKK13235.1 - 2.2e-43 148.4 5.5 2.4e-43 148.2 3.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Glyco_hydro_2_N PF02837.13 KKK13236.1 - 7.4e-25 87.4 0.0 1.8e-24 86.1 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.12 KKK13236.1 - 9.8e-12 44.3 0.0 2.9e-11 42.8 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2 PF00703.16 KKK13236.1 - 1.5e-08 35.0 2.0 9.2e-07 29.2 0.0 2.4 2 0 0 2 2 2 2 Glycosyl hydrolases family 2 HLH PF00010.21 KKK13238.1 - 3.1e-06 26.7 1.1 6.8e-06 25.6 0.8 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain adh_short PF00106.20 KKK13239.1 - 1.3e-29 103.2 0.3 1.8e-29 102.8 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KKK13239.1 - 2e-20 73.5 0.0 2.8e-20 73.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KKK13239.1 - 5.1e-10 39.3 0.0 6.9e-10 38.8 0.0 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KKK13239.1 - 2e-06 27.9 0.0 3e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding DUF1776 PF08643.5 KKK13239.1 - 0.00016 20.8 0.0 0.00022 20.4 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.16 KKK13239.1 - 0.0015 18.0 0.1 0.0037 16.7 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 KKK13239.1 - 0.0067 15.7 0.2 0.079 12.1 0.1 2.0 2 0 0 2 2 2 1 NmrA-like family Eno-Rase_NADH_b PF12242.3 KKK13239.1 - 0.021 14.6 0.2 0.044 13.5 0.1 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase RmlD_sub_bind PF04321.12 KKK13239.1 - 0.14 11.0 0.0 0.21 10.4 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain DIOX_N PF14226.1 KKK13240.1 - 8.8e-23 81.0 0.1 1.4e-22 80.4 0.1 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KKK13240.1 - 1.6e-15 57.2 0.0 4.1e-15 55.8 0.0 1.8 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily OrgA_MxiK PF09482.5 KKK13240.1 - 0.13 11.9 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 Bacterial type III secretion apparatus protein (OrgA_MxiK) DUF3433 PF11915.3 KKK13241.1 - 4.4e-43 145.3 10.8 1.9e-23 82.4 2.3 3.8 4 0 0 4 4 4 2 Protein of unknown function (DUF3433) Wzy_C PF04932.10 KKK13241.1 - 0.018 14.8 0.0 14 5.4 0.0 3.5 3 1 0 3 3 3 0 O-Antigen ligase RNA_pol_A_bac PF01000.21 KKK13243.1 - 5.3e-32 110.2 0.0 8.4e-32 109.6 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 KKK13243.1 - 2.6e-13 48.8 0.0 3.4e-13 48.4 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain NUDIX PF00293.23 KKK13244.1 - 9.1e-16 57.7 0.1 1.1e-15 57.4 0.1 1.1 1 0 0 1 1 1 1 NUDIX domain Cytochrom_C PF00034.16 KKK13245.1 - 2.2e-10 41.2 0.0 4e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.1 KKK13245.1 - 1.4e-07 31.5 2.9 2.4e-06 27.6 2.0 2.1 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.1 KKK13245.1 - 5.6e-05 22.6 0.1 0.00013 21.4 0.0 1.7 2 0 0 2 2 2 1 Cytochrome c-550 domain Cytochrome-c551 PF10643.4 KKK13245.1 - 0.0096 15.2 0.1 0.014 14.7 0.0 1.2 1 0 0 1 1 1 1 Photosystem P840 reaction-centre cytochrome c-551 Haem_bd PF14376.1 KKK13245.1 - 0.037 13.7 0.1 0.072 12.7 0.1 1.5 2 0 0 2 2 2 0 Haem-binding domain Baculo_PEP_C PF04513.7 KKK13246.1 - 0.093 12.5 2.7 0.26 11.1 0.1 2.4 1 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus RNase_PH PF01138.16 KKK13247.1 - 1.2e-07 32.1 0.0 3.4e-07 30.6 0.0 1.8 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 KKK13247.1 - 0.042 13.7 0.0 1.7 8.6 0.0 2.4 2 0 0 2 2 2 0 3' exoribonuclease family, domain 2 Nop14 PF04147.7 KKK13248.1 - 0.5 8.2 3.4 0.73 7.6 2.4 1.1 1 0 0 1 1 1 0 Nop14-like family ATE_C PF04377.10 KKK13249.1 - 6.8e-47 158.7 3.3 1.2e-46 157.9 2.3 1.4 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.8 KKK13249.1 - 1.5e-15 56.7 1.0 1.5e-15 56.7 0.7 2.2 3 0 0 3 3 3 1 Arginine-tRNA-protein transferase, N terminus Acetyltransf_6 PF13480.1 KKK13249.1 - 8.3e-05 22.5 0.3 0.00016 21.6 0.2 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Kelch_2 PF07646.10 KKK13249.1 - 0.004 16.8 0.2 0.2 11.4 0.0 2.6 2 0 0 2 2 2 1 Kelch motif Calcipressin PF04847.7 KKK13250.1 - 1.3e-32 112.8 2.7 2.2e-32 112.1 1.9 1.5 1 1 0 1 1 1 1 Calcipressin tRNA-synt_2d PF01409.15 KKK13251.1 - 4.2e-48 163.6 0.3 1.4e-25 89.9 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.9 KKK13251.1 - 2.7e-27 94.7 0.0 6.9e-27 93.4 0.0 1.7 2 0 0 2 2 2 1 Ferredoxin-fold anticodon binding domain GrpE PF01025.14 KKK13252.1 - 2.7e-42 144.1 5.8 3.8e-42 143.6 4.0 1.2 1 0 0 1 1 1 1 GrpE Focal_AT PF03623.8 KKK13252.1 - 0.073 12.5 0.7 0.12 11.8 0.5 1.4 1 1 0 1 1 1 0 Focal adhesion targeting region Mito_carr PF00153.22 KKK13253.1 - 4.9e-61 202.4 0.4 6.9e-20 70.5 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Urm1 PF09138.6 KKK13276.1 - 3.6e-35 119.9 0.1 4.3e-35 119.7 0.0 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.15 KKK13276.1 - 0.0007 19.9 0.0 0.00093 19.5 0.0 1.3 1 0 0 1 1 1 1 ThiS family Porin_3 PF01459.17 KKK13277.1 - 1.2e-83 280.6 0.1 1.4e-83 280.3 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic porin Zds_C PF08632.5 KKK13277.1 - 0.0099 15.2 0.0 0.022 14.1 0.0 1.5 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term FH2 PF02181.18 KKK13278.1 - 3.5e-88 295.9 3.2 4.6e-88 295.6 2.3 1.1 1 0 0 1 1 1 1 Formin Homology 2 Domain DUF2497 PF10691.4 KKK13278.1 - 0.15 12.0 1.3 3.1 7.8 0.0 3.1 4 0 0 4 4 4 0 Protein of unknown function (DUF2497) TrmE_N PF10396.4 KKK13279.1 - 2e-35 121.1 0.1 5.4e-35 119.8 0.0 1.8 2 0 0 2 2 2 1 GTP-binding protein TrmE N-terminus GTPase_Cys_C PF12631.2 KKK13279.1 - 1.7e-21 76.3 0.2 4.9e-21 74.9 0.1 1.8 1 1 0 1 1 1 1 Catalytic cysteine-containing C-terminus of GTPase, MnmE MMR_HSR1 PF01926.18 KKK13279.1 - 3.1e-16 59.3 0.0 5.2e-16 58.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KKK13279.1 - 2.9e-05 23.5 0.0 0.0025 17.2 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 KKK13279.1 - 4.3e-05 22.8 0.0 0.00018 20.7 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 KKK13279.1 - 9.1e-05 22.3 0.0 0.00015 21.6 0.0 1.3 1 0 0 1 1 1 1 Dynamin family Miro PF08477.8 KKK13279.1 - 0.00038 20.9 0.0 0.0012 19.3 0.0 1.9 1 1 0 1 1 1 1 Miro-like protein Glyco_hydro_3_C PF01915.17 KKK13279.1 - 0.028 13.9 0.1 0.046 13.2 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 3 C-terminal domain PGA_cap PF09587.5 KKK13279.1 - 0.13 11.6 0.1 0.22 10.8 0.1 1.4 1 0 0 1 1 1 0 Bacterial capsule synthesis protein PGA_cap cobW PF02492.14 KKK13279.1 - 0.14 11.5 0.0 2.3 7.6 0.0 2.1 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.1 KKK13279.1 - 0.15 11.6 0.2 9.4 5.8 0.0 2.8 3 0 0 3 3 3 0 P-loop containing region of AAA domain AAA_24 PF13479.1 KKK13279.1 - 0.18 11.3 0.0 0.43 10.1 0.0 1.7 2 0 0 2 2 2 0 AAA domain Ank_2 PF12796.2 KKK13280.1 - 9e-88 288.7 11.1 1e-18 67.4 0.5 7.6 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.25 KKK13280.1 - 1.2e-80 261.5 24.0 8.8e-08 31.5 0.0 14.0 14 0 0 14 14 14 13 Ankyrin repeat Ank_4 PF13637.1 KKK13280.1 - 2.1e-58 193.7 16.7 5.3e-10 39.5 0.0 7.9 6 1 0 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 KKK13280.1 - 1.6e-53 173.2 14.3 0.00027 20.9 0.0 14.5 14 0 0 14 14 14 13 Ankyrin repeat Ank_5 PF13857.1 KKK13280.1 - 2.3e-48 161.1 23.4 9.9e-09 35.1 0.0 11.4 2 2 10 12 12 12 11 Ankyrin repeats (many copies) Aconitase PF00330.15 KKK13281.1 - 7.7e-69 232.3 0.3 3.6e-43 147.7 0.0 2.6 1 1 1 2 2 2 2 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 KKK13281.1 - 1.2e-24 86.8 0.0 2e-24 86.1 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain FAD_binding_6 PF00970.19 KKK13281.1 - 5.9e-07 29.5 0.0 1.4e-06 28.3 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 KKK13281.1 - 7.2e-06 26.5 0.0 0.055 14.0 0.0 2.6 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 KKK13281.1 - 0.0038 17.1 0.0 0.0081 16.0 0.0 1.6 1 0 0 1 1 1 1 Ferric reductase NAD binding domain WD40 PF00400.27 KKK13282.1 - 2.4e-53 176.1 9.0 1.5e-07 31.0 0.0 10.6 11 0 0 11 11 11 8 WD domain, G-beta repeat 6PF2K PF01591.13 KKK13282.1 - 9.5e-42 142.5 0.0 1.5e-41 141.9 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 KKK13282.1 - 5.3e-22 78.6 0.4 1e-21 77.6 0.3 1.5 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 KKK13282.1 - 0.00088 19.1 0.0 0.0023 17.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KKK13282.1 - 0.032 15.0 0.0 0.27 12.0 0.0 2.3 1 1 1 2 2 2 0 AAA domain ABC_tran PF00005.22 KKK13283.1 - 1.5e-16 60.9 0.1 1.2e-15 58.0 0.1 2.2 2 1 0 2 2 1 1 ABC transporter AAA_21 PF13304.1 KKK13283.1 - 5.4e-11 42.9 0.9 5.1e-05 23.3 0.3 2.2 1 1 1 2 2 2 2 AAA domain AAA_15 PF13175.1 KKK13283.1 - 0.0003 19.9 0.0 0.15 11.1 0.0 2.1 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 KKK13283.1 - 0.00072 19.0 0.1 0.0013 18.1 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.1 KKK13283.1 - 0.0012 19.2 0.3 0.0025 18.1 0.2 1.5 1 0 0 1 1 1 1 AAA domain PduV-EutP PF10662.4 KKK13283.1 - 0.0015 18.0 0.0 0.0022 17.5 0.0 1.2 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_25 PF13481.1 KKK13283.1 - 0.0039 16.6 0.1 0.007 15.7 0.1 1.4 1 0 0 1 1 1 1 AAA domain DUF3584 PF12128.3 KKK13283.1 - 0.0051 14.2 0.1 0.0066 13.8 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) AAA_17 PF13207.1 KKK13283.1 - 0.01 16.6 0.4 0.035 14.9 0.2 2.0 1 1 0 2 2 2 0 AAA domain SMC_N PF02463.14 KKK13283.1 - 0.01 15.0 0.0 1.6 7.8 0.0 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_28 PF13521.1 KKK13283.1 - 0.013 15.4 0.1 0.027 14.4 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 KKK13283.1 - 0.015 15.2 0.0 0.059 13.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.17 KKK13283.1 - 0.02 14.3 0.1 0.03 13.7 0.1 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_10 PF12846.2 KKK13283.1 - 0.029 13.8 0.1 0.045 13.1 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain AAA_13 PF13166.1 KKK13283.1 - 0.049 12.1 0.1 0.068 11.6 0.1 1.1 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 KKK13283.1 - 0.052 13.4 0.1 0.11 12.3 0.0 1.7 1 1 0 1 1 1 0 AAA domain DUF258 PF03193.11 KKK13283.1 - 0.06 12.5 0.0 0.087 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 KKK13283.1 - 0.061 13.3 0.9 0.24 11.3 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain AAA PF00004.24 KKK13283.1 - 0.062 13.5 0.1 0.19 11.9 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Arf PF00025.16 KKK13283.1 - 0.075 12.2 0.1 0.17 11.1 0.1 1.5 1 0 0 1 1 1 0 ADP-ribosylation factor family AAA_22 PF13401.1 KKK13283.1 - 0.12 12.5 0.4 0.38 10.8 0.3 2.0 1 1 0 1 1 1 0 AAA domain IPPT PF01715.12 KKK13284.1 - 3e-54 183.6 0.1 6.7e-54 182.5 0.1 1.6 1 1 0 1 1 1 1 IPP transferase zf-C2H2_jaz PF12171.3 KKK13284.1 - 1.2e-06 28.4 0.7 2.4e-06 27.5 0.5 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KKK13284.1 - 2.6e-06 27.4 0.6 4.8e-06 26.5 0.4 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type AAA_17 PF13207.1 KKK13284.1 - 2.4e-05 25.1 0.6 8.2e-05 23.4 0.1 2.5 2 1 0 2 2 1 1 AAA domain AAA_33 PF13671.1 KKK13284.1 - 7.7e-05 22.5 0.4 0.068 13.0 0.0 3.2 3 1 0 4 4 4 2 AAA domain IPT PF01745.11 KKK13284.1 - 0.0015 17.7 0.0 0.0037 16.4 0.0 1.6 1 0 0 1 1 1 1 Isopentenyl transferase AAA_25 PF13481.1 KKK13284.1 - 0.0016 17.9 0.0 0.016 14.6 0.0 2.4 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.1 KKK13284.1 - 0.0028 17.9 1.4 0.04 14.2 0.1 3.2 3 1 0 3 3 3 1 AAA domain AAA_16 PF13191.1 KKK13284.1 - 0.0099 15.8 0.0 0.054 13.4 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KKK13284.1 - 0.035 14.2 0.0 0.11 12.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain AKAP95 PF04988.7 KKK13284.1 - 0.048 13.4 0.6 0.12 12.0 0.2 1.8 2 0 0 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) DUF87 PF01935.12 KKK13284.1 - 0.05 13.4 0.3 0.75 9.5 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function DUF87 zf-C2H2_2 PF12756.2 KKK13284.1 - 0.051 13.6 0.7 0.1 12.7 0.5 1.4 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) AAA_28 PF13521.1 KKK13284.1 - 0.084 12.8 0.8 0.42 10.5 0.0 2.5 3 0 0 3 3 3 0 AAA domain zf-C2H2 PF00096.21 KKK13284.1 - 0.15 12.4 0.2 0.3 11.5 0.1 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KKK13284.1 - 0.16 12.3 0.2 0.34 11.3 0.2 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger ABC_tran PF00005.22 KKK13284.1 - 0.35 11.1 2.4 0.42 10.8 0.3 2.6 2 1 0 2 2 1 0 ABC transporter RAI1 PF08652.6 KKK13285.1 - 1e-30 105.2 0.1 1.9e-30 104.4 0.0 1.4 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease DUF410 PF04190.8 KKK13286.1 - 7.9e-43 146.8 0.0 1e-42 146.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF410) Rep_fac_C PF08542.6 KKK13288.1 - 2.8e-20 72.0 0.0 5.4e-20 71.1 0.0 1.5 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 KKK13288.1 - 6.9e-13 48.5 0.0 5.9e-11 42.2 0.0 2.2 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 KKK13288.1 - 1.9e-11 44.3 0.0 3e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 KKK13288.1 - 2.7e-07 30.5 0.0 1.1e-06 28.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.13 KKK13288.1 - 9.2e-06 25.3 0.0 1.5e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase Rad17 PF03215.10 KKK13288.1 - 1.9e-05 23.5 0.0 0.015 14.0 0.0 2.5 2 1 0 3 3 3 2 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 KKK13288.1 - 2.2e-05 24.5 0.0 0.018 15.1 0.0 2.5 1 1 1 2 2 2 2 AAA domain AAA_16 PF13191.1 KKK13288.1 - 2.4e-05 24.4 0.0 0.00048 20.1 0.0 2.2 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.7 KKK13288.1 - 2.6e-05 23.3 0.0 8.1e-05 21.7 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_3 PF07726.6 KKK13288.1 - 0.00027 20.5 0.0 0.00051 19.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta PF06144.8 KKK13288.1 - 0.00052 19.5 0.0 0.00081 18.9 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_10 PF12846.2 KKK13288.1 - 0.0012 18.3 0.0 0.11 11.9 0.0 2.2 1 1 1 2 2 2 1 AAA-like domain Mg_chelatase PF01078.16 KKK13288.1 - 0.0016 17.6 0.0 0.018 14.1 0.0 2.1 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 KKK13288.1 - 0.002 17.8 0.0 0.0044 16.7 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_11 PF13086.1 KKK13288.1 - 0.0042 16.6 0.0 0.0076 15.8 0.0 1.3 1 1 0 1 1 1 1 AAA domain NTPase_1 PF03266.10 KKK13288.1 - 0.0067 16.1 0.2 0.056 13.1 0.1 2.3 1 1 1 2 2 2 1 NTPase DEAD PF00270.24 KKK13288.1 - 0.0095 15.4 0.2 0.36 10.3 0.0 2.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase ArgK PF03308.11 KKK13288.1 - 0.017 13.9 0.0 0.033 12.9 0.0 1.5 1 0 0 1 1 1 0 ArgK protein AAA_25 PF13481.1 KKK13288.1 - 0.043 13.2 0.0 0.18 11.2 0.0 2.1 2 1 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 KKK13288.1 - 0.051 13.0 0.0 0.099 12.1 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_18 PF13238.1 KKK13288.1 - 0.057 13.7 0.0 0.09 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_31 PF13614.1 KKK13288.1 - 0.1 12.5 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.5 KKK13288.1 - 0.12 11.5 0.0 0.2 10.8 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Amidase PF01425.16 KKK13289.1 - 1.5e-95 320.6 0.0 1.8e-95 320.3 0.0 1.0 1 0 0 1 1 1 1 Amidase Fungal_trans PF04082.13 KKK13290.1 - 9.4e-08 31.2 1.2 1.5e-07 30.5 0.8 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain AA_permease_2 PF13520.1 KKK13291.1 - 5.1e-64 216.3 40.6 9.1e-64 215.5 28.1 1.4 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KKK13291.1 - 1.2e-28 99.6 23.8 1.2e-28 99.6 16.5 2.2 2 0 0 2 2 2 2 Amino acid permease Peptidase_M28 PF04389.12 KKK13306.1 - 5.4e-32 110.9 0.0 7.5e-32 110.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 PriCT_2 PF08707.6 KKK13306.1 - 0.17 11.7 1.0 0.48 10.3 0.7 1.8 1 1 0 1 1 1 0 Primase C terminal 2 (PriCT-2) Sulf_transp PF04143.9 KKK13307.1 - 6.4e-16 58.1 11.9 1.8e-11 43.8 2.4 4.7 5 0 0 5 5 5 2 Sulphur transport DUF4341 PF14241.1 KKK13307.1 - 2.2e-09 36.8 0.9 2.2e-09 36.8 0.6 4.3 6 0 0 6 6 6 1 Domain of unknown function (DUF4341) PC_rep PF01851.17 KKK13308.1 - 5.6e-40 133.3 18.3 1.4e-09 37.6 0.0 9.6 9 0 0 9 9 9 7 Proteasome/cyclosome repeat HEAT_2 PF13646.1 KKK13308.1 - 2.9e-18 65.9 0.8 1.4e-12 47.7 0.0 4.5 3 1 2 5 5 5 3 HEAT repeats HEAT_EZ PF13513.1 KKK13308.1 - 5.5e-09 36.2 4.2 4.1e-06 27.1 0.0 4.7 4 1 1 5 5 5 2 HEAT-like repeat HEAT PF02985.17 KKK13308.1 - 1.3e-07 31.0 0.0 3.3 8.0 0.0 5.6 5 0 0 5 5 5 3 HEAT repeat RICTOR_V PF14668.1 KKK13308.1 - 0.085 12.8 0.2 5.7 6.9 0.0 3.3 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR, domain 5 HEAT_PBS PF03130.11 KKK13308.1 - 0.14 12.6 4.3 0.88 10.2 0.0 4.0 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat F-box PF00646.28 KKK13309.1 - 0.021 14.4 0.7 0.1 12.3 0.5 2.2 1 1 0 1 1 1 0 F-box domain F-box-like PF12937.2 KKK13309.1 - 0.046 13.4 0.6 0.046 13.4 0.4 2.6 3 0 0 3 3 3 0 F-box-like p450 PF00067.17 KKK13310.1 - 0.00039 19.0 0.3 0.00081 18.0 0.2 1.5 1 0 0 1 1 1 1 Cytochrome P450 GAS PF13851.1 KKK13310.1 - 0.0066 15.6 15.0 0.12 11.6 6.7 2.5 2 0 0 2 2 2 2 Growth-arrest specific micro-tubule binding Seryl_tRNA_N PF02403.17 KKK13310.1 - 0.0088 16.0 12.8 0.059 13.3 3.2 3.1 1 1 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain Reo_sigmaC PF04582.7 KKK13310.1 - 0.0094 15.1 1.1 0.015 14.5 0.7 1.3 1 0 0 1 1 1 1 Reovirus sigma C capsid protein Paralemmin PF03285.10 KKK13310.1 - 0.027 13.9 3.0 0.048 13.1 2.1 1.4 1 0 0 1 1 1 0 Paralemmin Filament PF00038.16 KKK13310.1 - 0.11 11.9 25.8 0.023 14.1 5.4 3.4 3 1 1 4 4 4 0 Intermediate filament protein COG5 PF10392.4 KKK13310.1 - 0.11 12.4 8.1 0.019 14.9 2.7 2.0 2 0 0 2 2 1 0 Golgi transport complex subunit 5 V-SNARE PF05008.10 KKK13310.1 - 0.29 11.3 9.4 0.022 14.8 2.9 2.0 2 0 0 2 2 1 0 Vesicle transport v-SNARE protein N-terminus FlaC_arch PF05377.6 KKK13310.1 - 0.31 10.9 3.7 0.38 10.6 0.4 2.8 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) IFT57 PF10498.4 KKK13310.1 - 0.5 9.0 11.3 0.94 8.1 7.8 1.3 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 DUF4140 PF13600.1 KKK13310.1 - 0.75 10.2 9.7 9.3 6.7 0.2 3.0 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Med4 PF10018.4 KKK13310.1 - 0.93 8.8 12.2 6.2 6.1 7.9 2.5 1 1 1 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 Mnd1 PF03962.10 KKK13310.1 - 0.97 9.0 14.5 0.026 14.1 3.0 2.4 2 1 0 2 2 2 0 Mnd1 family Laminin_II PF06009.7 KKK13310.1 - 1.1 9.0 8.1 0.7 9.6 1.8 2.6 3 0 0 3 3 3 0 Laminin Domain II DivIC PF04977.10 KKK13310.1 - 1.1 8.7 5.9 5.6 6.5 0.9 2.9 2 1 0 2 2 2 0 Septum formation initiator Prominin PF05478.6 KKK13310.1 - 1.3 6.4 3.7 2.2 5.7 2.6 1.3 1 0 0 1 1 1 0 Prominin DUF3461 PF11944.3 KKK13310.1 - 1.6 8.6 7.0 0.46 10.3 2.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3461) Fib_alpha PF08702.5 KKK13310.1 - 1.8 8.6 9.3 1.7 8.7 3.9 2.7 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family HlyD PF00529.15 KKK13310.1 - 3.2 6.9 10.5 5 6.3 6.6 1.8 1 1 1 2 2 2 0 HlyD family secretion protein DUF1664 PF07889.7 KKK13310.1 - 3.8 7.3 5.7 1.4 8.7 1.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Allexi_40kDa PF05549.6 KKK13310.1 - 4.9 6.3 8.8 2.6 7.2 3.6 2.1 2 1 0 2 2 2 0 Allexivirus 40kDa protein BLOC1_2 PF10046.4 KKK13310.1 - 5.2 7.2 8.7 1.2 9.2 2.3 2.7 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 HlyD_2 PF12700.2 KKK13310.1 - 6.4 5.8 6.9 1.3 8.0 1.7 1.8 2 0 0 2 2 2 0 HlyD family secretion protein DUF3450 PF11932.3 KKK13310.1 - 7.7 5.6 13.3 9 5.4 4.2 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF3450) PAXNEB PF05625.6 KKK13321.1 - 1.5e-128 428.6 0.0 1.7e-128 428.5 0.0 1.0 1 0 0 1 1 1 1 PAXNEB protein tRNA_int_endo PF01974.12 KKK13322.1 - 1.3e-15 56.9 0.0 2.3e-15 56.1 0.0 1.4 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain DUF2812 PF11193.3 KKK13322.1 - 0.082 13.0 2.4 0.18 11.9 1.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2812) GRIM-19 PF06212.7 KKK13322.1 - 0.097 12.3 2.0 0.21 11.2 0.4 1.9 2 0 0 2 2 2 0 GRIM-19 protein DUF1943 PF09172.6 KKK13322.1 - 0.16 10.8 2.7 0.23 10.2 1.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) DUF4038 PF13204.1 KKK13322.1 - 0.2 10.9 0.7 0.29 10.4 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4038) DUF3340 PF11818.3 KKK13322.1 - 0.49 10.3 6.7 0.76 9.7 4.6 1.2 1 0 0 1 1 1 0 C-terminal domain of tail specific protease (DUF3340) DEAD PF00270.24 KKK13323.1 - 5.2e-40 136.6 0.0 8.2e-40 136.0 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 KKK13323.1 - 1.1e-20 72.8 0.0 2.3e-20 71.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 KKK13323.1 - 6.9e-20 70.6 0.0 1.5e-19 69.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KKK13323.1 - 0.001 18.9 0.3 0.0028 17.4 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Neur_chan_memb PF02932.11 KKK13323.1 - 0.56 10.0 2.1 1.3 8.8 0.7 2.0 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region WD40 PF00400.27 KKK13324.1 - 1.8e-19 68.7 6.6 0.00043 20.0 0.3 7.2 7 1 0 7 7 7 4 WD domain, G-beta repeat Fungal_trans_2 PF11951.3 KKK13325.1 - 2.2e-10 39.6 1.5 6.4e-07 28.3 0.0 2.4 2 0 0 2 2 2 2 Fungal specific transcription factor domain MFS_1 PF07690.11 KKK13326.1 - 2.2e-26 92.4 25.7 2.2e-26 92.4 17.8 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF3382 PF11862.3 KKK13326.1 - 0.78 9.6 6.8 0.26 11.2 0.7 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3382) GATase PF00117.23 KKK13327.1 - 1.2e-11 44.4 0.0 1.6e-11 44.0 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 KKK13327.1 - 0.018 14.4 0.6 0.38 10.1 0.4 2.7 1 1 0 1 1 1 0 Peptidase C26 DUF775 PF05603.7 KKK13328.1 - 4.8e-66 222.1 0.1 5.4e-66 221.9 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF775) NUDIX PF00293.23 KKK13329.1 - 2.5e-12 46.5 0.0 3.4e-12 46.1 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain RNA_pol_Rpb8 PF03870.10 KKK13330.1 - 1.2e-36 125.8 0.0 1.4e-36 125.7 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 LRR_9 PF14580.1 KKK13331.1 - 3.9e-54 182.8 1.5 5.2e-54 182.4 0.0 1.7 2 0 0 2 2 2 1 Leucine-rich repeat LRR_4 PF12799.2 KKK13331.1 - 8.3e-09 34.8 4.1 0.0034 16.9 0.8 3.8 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KKK13331.1 - 9.8e-08 31.6 7.9 2.5e-05 23.9 1.3 2.7 2 1 1 3 3 3 2 Leucine rich repeat HTH_38 PF13936.1 KKK13331.1 - 0.069 12.7 1.8 0.11 12.0 0.6 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain DUF4349 PF14257.1 KKK13331.1 - 0.24 10.5 1.8 0.39 9.8 1.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) Ribonuc_2-5A PF06479.7 KKK13332.1 - 1.3e-41 141.4 0.0 2.2e-41 140.7 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase PF00069.20 KKK13332.1 - 2.8e-33 115.1 0.0 7.6e-30 103.9 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KKK13332.1 - 1.3e-14 53.9 0.0 9.6e-13 47.7 0.0 2.6 1 1 0 2 2 2 1 Protein tyrosine kinase PQQ PF01011.16 KKK13332.1 - 0.00019 20.7 0.0 0.075 12.5 0.0 3.0 2 0 0 2 2 2 2 PQQ enzyme repeat PQQ_2 PF13360.1 KKK13332.1 - 0.016 14.7 0.1 0.31 10.4 0.1 2.2 1 1 2 3 3 3 0 PQQ-like domain Cofilin_ADF PF00241.15 KKK13333.1 - 4e-11 42.8 0.0 4.8e-11 42.6 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein DUF1344 PF07076.6 KKK13333.1 - 0.13 11.8 0.1 0.26 10.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1344) FYVE_2 PF02318.11 KKK13334.1 - 0.64 9.9 20.4 0.32 10.8 1.9 3.3 3 0 0 3 3 3 0 FYVE-type zinc finger SNF2_N PF00176.18 KKK13335.1 - 1.7e-62 210.9 0.2 2.7e-62 210.2 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KKK13335.1 - 1.3e-10 40.9 0.0 1.6e-08 34.3 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 KKK13335.1 - 1.5e-07 31.0 0.0 3.5e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 KKK13335.1 - 5.2e-07 29.6 0.0 1.6e-06 28.1 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.3 KKK13335.1 - 3.6e-05 22.7 0.0 7.2e-05 21.7 0.0 1.4 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 UPF0086 PF01868.11 KKK13336.1 - 1.8e-31 107.6 0.1 3.8e-31 106.5 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function UPF0086 Pantoate_ligase PF02569.10 KKK13337.1 - 1.8e-80 269.7 0.0 3.4e-80 268.7 0.0 1.5 1 1 0 1 1 1 1 Pantoate-beta-alanine ligase Pyridox_oxase_2 PF12766.2 KKK13338.1 - 8.9e-25 86.9 0.0 1.9e-24 85.8 0.0 1.6 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Glyco_transf_34 PF05637.7 KKK13339.1 - 6.3e-14 52.0 0.0 3e-09 36.7 0.0 2.2 1 1 1 2 2 2 2 galactosyl transferase GMA12/MNN10 family DUF273 PF03314.9 KKK13339.1 - 0.00067 19.0 0.0 0.0011 18.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF273 Nucleotid_trans PF03407.11 KKK13339.1 - 0.13 12.0 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 Nucleotide-diphospho-sugar transferase p450 PF00067.17 KKK13340.1 - 1.2e-79 268.0 0.0 1.3e-79 267.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 KKK13341.1 - 5.2e-29 101.0 33.5 7e-18 64.4 19.8 2.5 2 1 1 3 3 3 2 Major Facilitator Superfamily DUF2109 PF09882.4 KKK13341.1 - 1.5 8.7 6.6 0.45 10.4 1.1 2.7 2 0 0 2 2 2 0 Predicted membrane protein (DUF2109) Ammonium_transp PF00909.16 KKK13342.1 - 5.4e-107 357.7 23.2 6.9e-107 357.3 16.1 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family GDA1_CD39 PF01150.12 KKK13343.1 - 5.9e-110 367.7 0.0 8.3e-110 367.2 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Acyltransferase PF01553.16 KKK13344.1 - 1.4e-17 63.3 0.0 3.2e-17 62.2 0.0 1.6 1 0 0 1 1 1 1 Acyltransferase HxlR PF01638.12 KKK13344.1 - 0.0097 15.5 0.1 0.47 10.1 0.1 3.1 2 0 0 2 2 2 1 HxlR-like helix-turn-helix Sds3 PF08598.6 KKK13345.1 - 0.017 14.6 1.3 0.11 11.9 0.1 2.1 2 0 0 2 2 2 0 Sds3-like RRM_6 PF14259.1 KKK13406.1 - 1.3e-05 25.0 0.0 0.069 13.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Ribosomal_L23 PF00276.15 KKK13406.1 - 0.15 12.0 0.0 0.27 11.1 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L23 LON PF02190.11 KKK13407.1 - 2.8e-24 85.9 0.0 4e-24 85.4 0.0 1.2 1 0 0 1 1 1 1 ATP-dependent protease La (LON) domain zf-RING_2 PF13639.1 KKK13407.1 - 8e-12 44.7 14.3 1.6e-08 34.2 6.3 2.4 2 0 0 2 2 2 2 Ring finger domain zf-C3HC4_2 PF13923.1 KKK13407.1 - 1.5e-10 40.8 17.9 3e-07 30.3 6.3 2.4 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KKK13407.1 - 5.9e-10 38.7 15.4 8.8e-07 28.5 4.8 2.4 2 0 0 2 2 2 2 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KKK13407.1 - 8.3e-10 38.1 10.9 5.2e-08 32.4 3.4 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KKK13407.1 - 4.8e-08 32.5 13.3 3.1e-06 26.7 5.7 2.4 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KKK13407.1 - 8.3e-05 22.3 24.5 0.0001 22.0 4.9 2.9 3 1 0 3 3 2 2 zinc finger of C3HC4-type, RING zf-P11 PF03854.9 KKK13407.1 - 0.0017 17.8 5.8 0.0017 17.8 4.0 2.0 2 0 0 2 2 2 1 P-11 zinc finger zf-RING_4 PF14570.1 KKK13407.1 - 0.01 15.3 6.1 0.045 13.3 3.0 2.6 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.1 KKK13407.1 - 0.012 15.2 16.5 0.016 14.9 1.8 3.3 3 0 0 3 3 3 0 RING-type zinc-finger U-box PF04564.10 KKK13407.1 - 0.025 14.5 0.0 0.06 13.3 0.0 1.6 1 0 0 1 1 1 0 U-box domain Cut8_M PF14483.1 KKK13407.1 - 0.054 13.3 0.9 0.1 12.4 0.2 1.8 2 0 0 2 2 2 0 Cut8 dimerisation domain zf-rbx1 PF12678.2 KKK13407.1 - 0.059 13.4 2.4 0.14 12.2 1.7 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger Ribosomal_L13 PF00572.13 KKK13408.1 - 8.3e-40 135.8 0.0 1e-39 135.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L13 Ribosomal_S9 PF00380.14 KKK13409.1 - 4.3e-34 117.3 0.2 4.7e-34 117.2 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Nckap1 PF09735.4 KKK13409.1 - 0.13 9.6 0.0 0.15 9.5 0.0 1.0 1 0 0 1 1 1 0 Membrane-associated apoptosis protein Lipase_3 PF01764.20 KKK13410.1 - 6.6e-32 110.0 0.0 9.6e-32 109.5 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.8 KKK13410.1 - 0.00064 19.3 0.0 0.0011 18.6 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 KKK13410.1 - 0.00078 19.2 0.0 0.0011 18.7 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KKK13410.1 - 0.0027 17.6 1.0 0.0062 16.4 0.5 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 KKK13410.1 - 0.003 17.0 0.0 0.0052 16.2 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Cutinase PF01083.17 KKK13410.1 - 0.034 13.8 0.0 0.062 13.0 0.0 1.4 1 0 0 1 1 1 0 Cutinase DUF2974 PF11187.3 KKK13410.1 - 0.093 12.0 0.0 0.64 9.3 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) DUF676 PF05057.9 KKK13410.1 - 0.15 11.3 0.0 0.22 10.7 0.0 1.1 1 0 0 1 1 1 0 Putative serine esterase (DUF676) HEAT_2 PF13646.1 KKK13423.1 - 1.8e-06 28.1 2.4 0.028 14.6 0.0 4.3 5 0 0 5 5 5 2 HEAT repeats HEAT_EZ PF13513.1 KKK13423.1 - 0.02 15.3 1.1 0.02 15.3 0.8 3.5 4 0 0 4 4 4 0 HEAT-like repeat Glyco_hydro_35 PF01301.14 KKK13423.1 - 0.1 11.9 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 35 HEAT PF02985.17 KKK13423.1 - 0.24 11.5 7.4 2.5 8.3 0.1 5.0 5 0 0 5 5 5 0 HEAT repeat eIF-5_eIF-2B PF01873.12 KKK13424.1 - 6.6e-39 132.4 0.0 1.1e-38 131.7 0.0 1.4 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.13 KKK13424.1 - 1.6e-26 92.0 0.9 3.6e-26 90.9 0.6 1.6 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon NOA36 PF06524.7 KKK13424.1 - 0.033 13.4 6.7 0.063 12.5 4.6 1.4 1 0 0 1 1 1 0 NOA36 protein MCM PF00493.18 KKK13425.1 - 1.6e-140 467.6 0.0 2.3e-140 467.1 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family VTC PF09359.5 KKK13425.1 - 3.8e-99 331.2 0.0 6.8e-99 330.4 0.0 1.4 1 0 0 1 1 1 1 VTC domain MCM_N PF14551.1 KKK13425.1 - 1.3e-24 87.0 0.0 7.2e-24 84.6 0.0 2.5 1 0 0 1 1 1 1 MCM N-terminal domain SPX PF03105.14 KKK13425.1 - 2.5e-24 86.5 10.7 1.5e-22 80.6 4.3 3.6 2 1 0 2 2 2 1 SPX domain DUF202 PF02656.10 KKK13425.1 - 6e-10 39.2 4.6 6e-10 39.2 3.2 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Mg_chelatase PF01078.16 KKK13425.1 - 1.4e-05 24.3 0.0 0.00027 20.1 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 KKK13425.1 - 4e-05 23.3 0.0 0.00011 21.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 KKK13425.1 - 0.0028 17.2 0.0 0.0063 16.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF999 PF06198.6 KKK13425.1 - 1.1 8.9 4.5 17 5.2 0.3 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF999) DNA_ligase_A_N PF04675.9 KKK13426.1 - 2.7e-56 190.1 0.1 6.5e-56 188.9 0.0 1.7 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_M PF01068.16 KKK13426.1 - 2.1e-50 170.9 0.9 2e-48 164.4 0.6 2.3 1 1 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_C PF04679.10 KKK13426.1 - 4.7e-27 94.2 0.0 1.8e-26 92.3 0.0 2.1 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region Ank_2 PF12796.2 KKK13427.1 - 6.5e-07 29.6 0.1 0.0067 16.7 0.0 2.7 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KKK13427.1 - 0.041 14.3 0.0 17 6.1 0.0 2.5 2 0 0 2 2 2 0 Ankyrin repeats (many copies) DUF3534 PF12053.3 KKK13427.1 - 0.12 12.2 1.2 14 5.5 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3534) DUF221 PF02714.10 KKK13428.1 - 5.6e-105 350.7 30.2 9.4e-105 350.0 20.9 1.4 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 KKK13428.1 - 8.9e-46 155.3 0.3 8.9e-46 155.3 0.2 3.4 3 1 1 4 4 4 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 KKK13428.1 - 7.3e-14 51.4 0.0 1.7e-13 50.2 0.0 1.6 1 0 0 1 1 1 1 Phosphate metabolism protein DUF4463 PF14703.1 KKK13428.1 - 4.4e-13 49.5 5.1 1.2e-05 25.7 0.0 3.2 3 0 0 3 3 3 2 Domain of unknown function (DUF4463) GP41 PF00517.12 KKK13428.1 - 0.013 15.0 4.4 0.064 12.8 2.1 2.8 2 1 0 2 2 2 0 Retroviral envelope protein DUF676 PF05057.9 KKK13429.1 - 5e-06 25.9 0.0 4e-05 23.0 0.0 2.1 2 0 0 2 2 2 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 KKK13429.1 - 0.0026 17.3 0.0 0.011 15.3 0.0 1.9 2 0 0 2 2 2 1 PGAP1-like protein Abhydrolase_6 PF12697.2 KKK13429.1 - 0.01 15.7 0.0 0.024 14.5 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_8 PF06259.7 KKK13429.1 - 0.12 11.8 0.0 0.26 10.7 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase Cpn60_TCP1 PF00118.19 KKK13431.1 - 2.1e-118 396.0 6.2 2.4e-118 395.8 4.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF1547 PF07577.6 KKK13431.1 - 0.19 11.4 1.6 0.57 9.8 0.2 2.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1547) OB_NTP_bind PF07717.11 KKK13434.1 - 1.2e-18 66.9 0.0 2.6e-18 65.9 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 KKK13434.1 - 1.5e-17 63.4 0.1 3.8e-17 62.1 0.1 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 KKK13434.1 - 1e-11 44.5 0.0 4.2e-11 42.5 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_29 PF13555.1 KKK13434.1 - 0.0019 17.7 0.0 0.0059 16.1 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.1 KKK13434.1 - 0.0024 18.0 0.0 0.0058 16.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain FtsK_SpoIIIE PF01580.13 KKK13434.1 - 0.022 14.2 0.0 0.049 13.1 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family ABC_tran PF00005.22 KKK13434.1 - 0.028 14.7 0.0 0.099 12.9 0.0 1.9 1 0 0 1 1 1 0 ABC transporter KaiC PF06745.8 KKK13434.1 - 0.034 13.2 0.0 0.07 12.2 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_25 PF13481.1 KKK13434.1 - 0.11 11.9 0.0 0.26 10.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain F-box-like PF12937.2 KKK13435.1 - 3.1e-09 36.4 0.1 6.2e-09 35.4 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KKK13435.1 - 4.3e-06 26.2 0.1 1.1e-05 24.9 0.1 1.7 1 0 0 1 1 1 1 F-box domain MIT PF04212.13 KKK13435.1 - 0.019 14.8 0.4 0.041 13.7 0.3 1.5 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain TPR_11 PF13414.1 KKK13435.1 - 0.045 13.4 0.9 0.088 12.4 0.6 1.5 1 0 0 1 1 1 0 TPR repeat TPR_2 PF07719.12 KKK13435.1 - 0.094 12.6 0.8 1.1 9.3 0.7 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat Mito_carr PF00153.22 KKK13436.1 - 2.8e-63 209.6 1.6 5.1e-20 70.9 0.0 4.2 3 1 0 3 3 3 3 Mitochondrial carrier protein ATP-synt_Eps PF04627.8 KKK13437.1 - 2.9e-23 81.1 0.9 4.4e-23 80.5 0.6 1.3 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain Mak10 PF04112.8 KKK13438.1 - 2.5e-57 192.7 0.0 4.4e-57 191.9 0.0 1.4 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase Fungal_trans PF04082.13 KKK13438.1 - 6e-11 41.6 0.3 1.5e-10 40.3 0.2 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK13438.1 - 3e-09 36.6 9.3 3e-09 36.6 6.4 2.2 1 1 1 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_L7Ae PF01248.21 KKK13439.1 - 1.5e-25 88.5 0.0 1.7e-25 88.3 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Ribosomal_L16 PF00252.13 KKK13440.1 - 2.7e-32 111.3 0.2 3.4e-32 110.9 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Lyase_aromatic PF00221.14 KKK13441.1 - 2e-159 531.0 3.8 2.7e-159 530.5 2.6 1.0 1 0 0 1 1 1 1 Aromatic amino acid lyase SNF2_N PF00176.18 KKK13442.1 - 2.4e-23 82.3 0.3 8.1e-15 54.3 0.0 2.3 2 0 0 2 2 2 2 SNF2 family N-terminal domain DNA_methylase PF00145.12 KKK13442.1 - 1.6e-17 63.6 0.0 3.4e-17 62.5 0.0 1.6 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase Helicase_C PF00271.26 KKK13442.1 - 0.00013 21.7 0.3 0.00034 20.4 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-RING_5 PF14634.1 KKK13442.1 - 0.0042 16.7 6.8 0.0042 16.7 4.7 3.0 3 0 0 3 3 3 2 zinc-RING finger domain zf-piccolo PF05715.8 KKK13442.1 - 0.061 13.3 1.8 0.26 11.3 1.2 2.1 1 0 0 1 1 1 0 Piccolo Zn-finger zf-C3HC4_2 PF13923.1 KKK13442.1 - 0.76 9.8 17.7 0.14 12.2 3.1 2.7 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KKK13442.1 - 9.6 5.9 18.9 0.85 9.3 3.7 2.7 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Band_7 PF01145.20 KKK13443.1 - 1.4e-23 83.7 2.4 1.9e-23 83.3 1.7 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family CSTF2_hinge PF14327.1 KKK13444.1 - 1e-30 105.6 2.5 1e-30 105.6 1.8 2.3 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.17 KKK13444.1 - 1.9e-19 69.0 0.0 3e-19 68.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KKK13444.1 - 3.1e-16 59.0 0.0 5.8e-16 58.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.1 KKK13444.1 - 5.3e-16 57.6 13.9 5.3e-16 57.6 9.6 2.1 2 0 0 2 2 2 1 Transcription termination and cleavage factor C-terminal RRM_5 PF13893.1 KKK13444.1 - 2.1e-07 30.6 0.0 3.2e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Spo7_2_N PF15407.1 KKK13444.1 - 0.045 13.2 0.0 0.089 12.2 0.0 1.5 1 0 0 1 1 1 0 Sporulation protein family 7 RrnaAD PF00398.15 KKK13444.1 - 0.12 11.3 0.0 0.26 10.2 0.0 1.5 2 0 0 2 2 2 0 Ribosomal RNA adenine dimethylase DUF2523 PF10734.4 KKK13444.1 - 0.14 12.4 0.2 3.4 7.9 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2523) Sua5_yciO_yrdC PF01300.13 KKK13445.1 - 5.7e-55 185.3 0.0 1.4e-54 184.0 0.0 1.7 1 0 0 1 1 1 1 Telomere recombination DUF3441 PF11923.3 KKK13445.1 - 2.4e-39 133.4 0.1 2.4e-39 133.4 0.1 2.7 3 0 0 3 3 3 1 Domain of unknown function (DUF3441) SUA5 PF03481.8 KKK13445.1 - 1.7e-26 92.7 0.1 1.6e-25 89.5 0.0 2.7 2 0 0 2 2 2 1 Putative GTP-binding controlling metal-binding FbpA PF05833.6 KKK13445.1 - 5.2e-18 64.8 14.6 3.6e-13 48.8 0.1 3.9 3 1 1 4 4 4 2 Fibronectin-binding protein A N-terminus (FbpA) DUF814 PF05670.8 KKK13445.1 - 6.3e-16 58.0 0.0 1.5e-15 56.8 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF814) Clat_adaptor_s PF01217.15 KKK13445.1 - 4.3e-10 39.4 0.0 1.8e-08 34.2 0.1 2.8 3 0 0 3 3 3 1 Clathrin adaptor complex small chain 2Fe-2S_thioredx PF01257.14 KKK13447.1 - 5.6e-60 201.1 0.0 7.5e-60 200.7 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin A_deaminase PF00962.17 KKK13448.1 - 5.6e-75 252.3 0.0 6.3e-75 252.1 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase Amidohydro_4 PF13147.1 KKK13448.1 - 0.00026 21.1 0.1 0.00063 19.8 0.1 1.7 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_3 PF07969.6 KKK13448.1 - 0.039 13.1 0.1 0.078 12.1 0.0 1.5 1 1 0 1 1 1 0 Amidohydrolase family Cytomega_TRL10 PF06084.6 KKK13449.1 - 1.9 8.2 6.9 0.57 9.9 1.9 2.1 2 0 0 2 2 2 0 Cytomegalovirus TRL10 protein TrkH PF02386.11 KKK13450.1 - 2.6e-103 345.3 3.1 2.6e-103 345.3 2.1 1.9 2 0 0 2 2 2 1 Cation transport protein SelP_N PF04592.9 KKK13450.1 - 0.76 9.1 5.5 1.3 8.3 3.8 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Metallophos_C PF14008.1 KKK13451.1 - 9.6e-21 73.6 1.2 4.2e-20 71.5 0.2 2.4 2 0 0 2 2 2 1 Iron/zinc purple acid phosphatase-like protein C Metallophos PF00149.23 KKK13451.1 - 1.5e-12 47.3 0.1 2.9e-12 46.4 0.1 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase TPMT PF05724.6 KKK13452.1 - 6.3e-28 97.6 0.0 1.4e-27 96.6 0.0 1.6 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_23 PF13489.1 KKK13452.1 - 1.4e-07 31.4 0.0 1.9e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KKK13452.1 - 1.9e-07 31.6 0.0 3e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KKK13452.1 - 3.5e-05 23.8 0.0 6.4e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KKK13452.1 - 8.5e-05 22.1 0.0 0.071 12.7 0.0 2.1 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.7 KKK13452.1 - 0.00015 22.1 0.0 0.00042 20.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KKK13452.1 - 0.0009 19.5 0.0 0.0022 18.3 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain N2227 PF07942.7 KKK13452.1 - 0.025 13.5 0.0 0.036 13.0 0.0 1.1 1 0 0 1 1 1 0 N2227-like protein Methyltransf_12 PF08242.7 KKK13452.1 - 0.029 14.8 0.0 0.076 13.4 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain MetW PF07021.7 KKK13452.1 - 0.17 11.2 0.0 0.24 10.7 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW adh_short PF00106.20 KKK13453.1 - 3.1e-25 89.0 0.1 6.7e-25 87.9 0.0 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KKK13453.1 - 6e-24 85.1 0.0 8.6e-24 84.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KKK13453.1 - 5.2e-12 45.7 0.3 4e-11 42.9 0.2 2.3 1 1 0 1 1 1 1 KR domain 3Beta_HSD PF01073.14 KKK13453.1 - 0.0085 14.8 0.0 0.022 13.4 0.0 1.7 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 KKK13453.1 - 0.015 14.7 0.0 0.027 13.9 0.0 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_7 PF13241.1 KKK13453.1 - 0.079 13.2 0.0 0.25 11.6 0.0 1.9 2 1 0 2 2 2 0 Putative NAD(P)-binding Peptidase_M14 PF00246.19 KKK13455.1 - 8.8e-69 232.1 0.0 1.1e-68 231.8 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase AA_permease PF00324.16 KKK13456.1 - 1.8e-112 376.1 40.8 2.4e-111 372.4 28.3 1.9 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KKK13456.1 - 2.5e-30 105.4 39.8 1.9e-29 102.5 27.6 2.0 1 1 0 1 1 1 1 Amino acid permease NicO PF03824.11 KKK13458.1 - 1.1e-57 195.5 17.1 9.4e-56 189.1 3.5 2.6 3 0 0 3 3 3 2 High-affinity nickel-transport protein MIG-14_Wnt-bd PF06664.7 KKK13458.1 - 0.049 12.4 6.8 0.14 10.9 1.6 2.2 2 0 0 2 2 2 0 Wnt-binding factor required for Wnt secretion DNA_pol_lambd_f PF10391.4 KKK13459.1 - 2.3e-18 65.4 0.1 4.1e-18 64.6 0.1 1.5 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda DNA_pol_B_thumb PF14791.1 KKK13459.1 - 4.9e-17 61.3 0.0 1.4e-16 59.8 0.0 1.9 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_B_palm PF14792.1 KKK13459.1 - 6e-16 58.4 0.1 2.1e-15 56.7 0.1 1.9 1 1 0 1 1 1 1 DNA polymerase beta palm HHH_8 PF14716.1 KKK13459.1 - 7.6e-11 42.0 0.0 1.2e-09 38.1 0.1 2.3 2 0 0 2 2 2 1 Helix-hairpin-helix domain NTP_transf_2 PF01909.18 KKK13459.1 - 0.011 16.0 0.0 0.038 14.3 0.0 1.9 1 0 0 1 1 1 0 Nucleotidyltransferase domain IMS_HHH PF11798.3 KKK13459.1 - 0.12 12.4 0.0 0.37 10.9 0.0 1.8 1 0 0 1 1 1 0 IMS family HHH motif Ribosomal_L7Ae PF01248.21 KKK13460.1 - 3.3e-19 68.2 1.1 3e-18 65.1 0.8 2.3 1 1 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family 2-Hacid_dh_C PF02826.14 KKK13463.1 - 4e-41 140.1 0.0 5.4e-41 139.6 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KKK13463.1 - 4.5e-06 26.1 0.0 6.3e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain F420_oxidored PF03807.12 KKK13463.1 - 0.00035 20.9 0.3 0.0011 19.3 0.0 1.9 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent IlvN PF07991.7 KKK13463.1 - 0.0023 17.3 0.0 0.0039 16.5 0.0 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_2 PF03446.10 KKK13463.1 - 0.0031 17.3 0.1 0.0057 16.5 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.13 KKK13463.1 - 0.0038 16.8 0.0 0.0064 16.1 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 KKK13463.1 - 0.015 15.3 0.0 0.029 14.3 0.0 1.5 1 0 0 1 1 1 0 NADH(P)-binding XdhC_C PF13478.1 KKK13463.1 - 0.027 14.7 0.0 0.05 13.9 0.0 1.4 1 0 0 1 1 1 0 XdhC Rossmann domain AlaDh_PNT_C PF01262.16 KKK13463.1 - 0.13 11.7 0.7 1.2 8.7 0.1 2.5 2 1 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_Gly3P_dh_N PF01210.18 KKK13463.1 - 0.22 11.2 1.2 1.9 8.2 0.1 2.5 2 1 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus OPT PF03169.10 KKK13464.1 - 8.5e-180 599.2 17.2 9.8e-180 599.0 11.9 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF4212 PF13937.1 KKK13464.1 - 0.76 9.8 9.7 4.1 7.4 0.1 4.4 4 0 0 4 4 4 0 Domain of unknown function (DUF4212) SH3_9 PF14604.1 KKK13465.1 - 1.7e-10 40.3 0.0 2.7e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KKK13465.1 - 1.8e-07 30.4 0.0 3.1e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KKK13465.1 - 4e-07 29.4 0.0 9.1e-07 28.2 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Peptidase_M56 PF05569.6 KKK13465.1 - 0.037 13.0 0.3 0.059 12.3 0.1 1.4 1 1 0 1 1 1 0 BlaR1 peptidase M56 Macoilin PF09726.4 KKK13465.1 - 0.039 12.2 4.4 0.043 12.1 3.0 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF3619 PF12279.3 KKK13465.1 - 0.07 13.2 0.2 0.19 11.8 0.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3619) MtrF PF09472.5 KKK13465.1 - 0.075 12.2 2.4 0.15 11.3 1.7 1.5 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) DUF3042 PF11240.3 KKK13465.1 - 0.12 12.1 3.9 0.64 9.8 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3042) Rifin_STEVOR PF02009.11 KKK13465.1 - 0.77 9.3 9.4 2.5 7.6 6.6 1.7 1 1 0 1 1 1 0 Rifin/stevor family DUF4448 PF14610.1 KKK13465.1 - 0.91 8.9 7.3 0.072 12.5 1.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) SKG6 PF08693.5 KKK13465.1 - 1.2 8.4 5.1 0.28 10.5 0.1 2.4 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Pkinase PF00069.20 KKK13466.1 - 9.3e-44 149.5 0.0 1.4e-43 148.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK13466.1 - 4.7e-16 58.6 0.0 6.9e-16 58.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KKK13466.1 - 0.0005 19.8 0.2 0.36 10.5 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family KIX PF02172.11 KKK13466.1 - 0.00072 19.5 0.4 0.0014 18.6 0.2 1.4 1 0 0 1 1 1 1 KIX domain Kdo PF06293.9 KKK13466.1 - 0.016 14.3 0.0 0.17 10.9 0.0 2.1 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KKK13466.1 - 0.028 13.3 0.1 0.066 12.1 0.0 1.7 2 0 0 2 2 2 0 Kinase-like YrbL-PhoP_reg PF10707.4 KKK13466.1 - 0.062 12.6 0.0 0.14 11.4 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL WPP PF13943.1 KKK13466.1 - 0.15 12.3 3.0 0.43 10.8 1.1 2.3 2 0 0 2 2 2 0 WPP domain muHD PF10291.4 KKK13467.1 - 3.1e-88 295.2 0.3 4.5e-88 294.7 0.2 1.3 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain FCH PF00611.18 KKK13467.1 - 2.9e-11 43.3 0.5 1.3e-10 41.2 0.0 2.3 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain MAD PF05557.8 KKK13468.1 - 1.6e-53 181.9 77.6 1.7e-44 152.1 53.7 2.0 2 0 0 2 2 2 2 Mitotic checkpoint protein TATR PF03430.8 KKK13469.1 - 1.6 7.3 2.7 2.8 6.4 1.8 1.3 1 0 0 1 1 1 0 Trans-activating transcriptional regulator DUF3115 PF11312.3 KKK13470.1 - 2.2e-109 365.1 0.0 3.2e-109 364.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3115) Band_7 PF01145.20 KKK13471.1 - 1.1e-24 87.3 7.0 1.2e-24 87.2 3.8 1.7 1 1 1 2 2 2 1 SPFH domain / Band 7 family DUF2884 PF11101.3 KKK13471.1 - 0.029 13.7 0.7 0.052 12.9 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2884) MMR_HSR1_C PF08438.5 KKK13474.1 - 9.3e-32 109.5 0.0 1.9e-31 108.5 0.0 1.5 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.18 KKK13474.1 - 2.1e-13 50.2 0.0 4.6e-13 49.1 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 KKK13474.1 - 0.00058 19.7 1.2 0.32 10.8 0.4 2.9 3 0 0 3 3 3 1 Dynamin family FeoB_N PF02421.13 KKK13474.1 - 0.00068 18.9 0.1 0.0055 15.9 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 KKK13474.1 - 0.0098 15.3 0.1 4 6.8 0.0 2.7 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain ArgK PF03308.11 KKK13474.1 - 0.018 13.8 0.1 0.13 10.9 0.0 2.1 2 0 0 2 2 2 0 ArgK protein RHD3 PF05879.7 KKK13474.1 - 0.028 12.3 0.6 0.26 9.1 0.0 2.0 2 0 0 2 2 2 0 Root hair defective 3 GTP-binding protein (RHD3) ABC_tran PF00005.22 KKK13474.1 - 0.042 14.1 0.0 0.3 11.3 0.0 2.1 2 0 0 2 2 2 0 ABC transporter AAA_30 PF13604.1 KKK13474.1 - 0.045 13.3 0.0 0.45 10.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 KKK13474.1 - 0.051 13.8 0.1 2.8 8.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 KKK13474.1 - 0.081 12.7 0.1 4.6 7.1 0.1 2.3 2 0 0 2 2 2 0 AAA domain KTI12 PF08433.5 KKK13474.1 - 0.14 11.3 0.1 0.31 10.2 0.1 1.5 1 0 0 1 1 1 0 Chromatin associated protein KTI12 UcrQ PF02939.11 KKK13476.1 - 2.9e-29 100.6 0.1 3.5e-29 100.4 0.0 1.0 1 0 0 1 1 1 1 UcrQ family Spermine_synth PF01564.12 KKK13477.1 - 5.3e-97 323.5 0.0 6.8e-97 323.2 0.0 1.0 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_31 PF13847.1 KKK13477.1 - 5.9e-05 22.7 0.0 9.1e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KKK13477.1 - 0.0015 18.9 0.1 0.034 14.6 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KKK13477.1 - 0.0026 18.3 0.0 0.005 17.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.13 KKK13477.1 - 0.0065 15.6 0.2 0.023 13.9 0.1 1.9 1 1 1 2 2 2 1 O-methyltransferase MTS PF05175.9 KKK13477.1 - 0.088 12.1 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_24 PF13578.1 KKK13477.1 - 0.094 13.5 0.0 0.21 12.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Transketolase_N PF00456.16 KKK13478.1 - 4.3e-133 443.2 0.8 8.9e-67 225.2 0.1 2.2 1 1 1 2 2 2 2 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 KKK13478.1 - 4e-44 150.2 0.0 7.1e-44 149.4 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 KKK13478.1 - 4.8e-13 49.1 0.0 1.1e-12 47.9 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.1 KKK13478.1 - 0.003 16.5 0.1 0.37 9.6 0.1 2.5 2 1 1 3 3 3 2 1-deoxy-D-xylulose-5-phosphate synthase Fungal_trans PF04082.13 KKK13479.1 - 4.6e-38 130.5 0.1 8.8e-38 129.6 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK13479.1 - 1.6e-08 34.2 14.9 2.8e-08 33.5 10.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Striatin PF08232.7 KKK13479.1 - 0.032 14.5 0.9 2.9 8.1 0.0 2.6 2 0 0 2 2 2 0 Striatin family Cep57_MT_bd PF06657.8 KKK13479.1 - 0.056 13.3 1.3 14 5.7 0.1 2.7 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 DUF4635 PF15466.1 KKK13479.1 - 0.21 10.8 1.3 0.34 10.2 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4635) Tyrosinase PF00264.15 KKK13480.1 - 1.7e-49 168.9 0.1 2.6e-49 168.3 0.1 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase Abhydrolase_6 PF12697.2 KKK13481.1 - 1.1e-22 81.0 3.0 1.5e-22 80.6 2.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KKK13481.1 - 1e-09 38.3 0.0 1.6e-09 37.6 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KKK13481.1 - 6.3e-07 29.1 0.0 3.1e-05 23.6 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold ADP_ribosyl_GH PF03747.9 KKK13482.1 - 6e-57 193.6 0.3 6.8e-57 193.4 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase RabGAP-TBC PF00566.13 KKK13484.1 - 1.9e-47 161.5 0.7 1.4e-46 158.6 0.0 2.4 3 0 0 3 3 3 1 Rab-GTPase-TBC domain Spc24 PF08286.6 KKK13484.1 - 1.2 8.8 7.7 2.9 7.6 1.8 3.2 3 0 0 3 3 3 0 Spc24 subunit of Ndc80 DNA_topoisoIV PF00521.15 KKK13485.1 - 4.1e-134 447.6 0.1 8.3e-134 446.6 0.0 1.5 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseB PF00204.20 KKK13485.1 - 4.8e-34 117.0 0.4 1.3e-33 115.6 0.3 1.7 1 0 0 1 1 1 1 DNA gyrase B Toprim PF01751.17 KKK13485.1 - 1.7e-14 53.6 0.0 9.1e-14 51.2 0.0 2.4 1 0 0 1 1 1 1 Toprim domain HATPase_c PF02518.21 KKK13485.1 - 6.1e-11 42.0 0.0 1.6e-10 40.7 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Patatin PF01734.17 KKK13486.1 - 3.4e-15 56.5 0.0 7.6e-15 55.3 0.0 1.6 1 1 0 1 1 1 1 Patatin-like phospholipase Fungal_trans PF04082.13 KKK13487.1 - 8.2e-13 47.8 1.0 1.5e-12 46.9 0.7 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK13487.1 - 3e-09 36.6 9.1 5.6e-09 35.7 6.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cutinase PF01083.17 KKK13488.1 - 3.1e-50 170.3 7.7 3.6e-50 170.1 5.4 1.0 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.6 KKK13488.1 - 8.9e-05 22.0 1.4 0.0016 17.9 0.1 2.1 1 1 1 2 2 2 2 PE-PPE domain Abhydrolase_6 PF12697.2 KKK13488.1 - 0.049 13.4 0.1 0.056 13.3 0.1 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family PAN_1 PF00024.21 KKK13489.1 - 0.022 14.4 0.8 0.033 13.9 0.6 1.3 1 0 0 1 1 1 0 PAN domain Reticulon PF02453.12 KKK13491.1 - 1.2e-39 135.6 4.4 1.5e-39 135.2 3.0 1.1 1 0 0 1 1 1 1 Reticulon Cytochrome-c551 PF10643.4 KKK13491.1 - 0.12 11.6 0.6 0.26 10.5 0.3 1.4 1 1 0 1 1 1 0 Photosystem P840 reaction-centre cytochrome c-551 INCENP_ARK-bind PF03941.10 KKK13492.1 - 1.8e-18 66.1 0.3 1.8e-18 66.1 0.2 2.5 2 0 0 2 2 2 1 Inner centromere protein, ARK binding region FA_hydroxylase PF04116.8 KKK13495.1 - 2.7e-13 50.2 18.3 2.7e-13 50.2 12.7 2.3 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Colicin_V PF02674.11 KKK13495.1 - 1.3 8.8 7.0 0.42 10.4 0.3 2.6 3 0 0 3 3 3 0 Colicin V production protein Ribosomal_L37ae PF01780.14 KKK13503.1 - 6e-41 138.2 10.1 6.6e-41 138.0 7.0 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family A2L_zn_ribbon PF08792.5 KKK13503.1 - 0.0012 18.1 3.6 0.089 12.2 0.1 2.2 2 0 0 2 2 2 2 A2L zinc ribbon domain Zn_Tnp_IS1595 PF12760.2 KKK13503.1 - 0.0018 18.0 3.3 0.0025 17.5 2.3 1.3 1 0 0 1 1 1 1 Transposase zinc-ribbon domain Sgf11 PF08209.6 KKK13503.1 - 0.12 11.7 0.6 0.85 8.9 0.0 2.2 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) zf-BED PF02892.10 KKK13503.1 - 0.13 11.9 4.5 1.6 8.5 0.2 2.4 1 1 1 2 2 2 0 BED zinc finger Zn-ribbon_8 PF09723.5 KKK13503.1 - 0.18 11.7 1.8 0.96 9.4 0.1 2.2 2 0 0 2 2 2 0 Zinc ribbon domain NOB1_Zn_bind PF08772.6 KKK13503.1 - 0.2 11.5 3.4 1.9 8.3 2.6 2.1 1 1 1 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like CarbpepA_inh PF02977.10 KKK13503.1 - 0.39 10.3 4.5 0.38 10.3 0.3 2.1 1 1 1 2 2 2 0 Carboxypeptidase A inhibitor zf-C2H2 PF00096.21 KKK13503.1 - 0.72 10.3 3.4 7.3 7.1 0.2 2.4 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KKK13503.1 - 2 8.8 6.0 3.6 8.0 0.5 2.2 1 1 1 2 2 2 0 Zinc-finger double domain Pinin_SDK_memA PF04696.8 KKK13504.1 - 7.3e-29 100.0 21.6 1.4e-28 99.1 9.0 2.3 2 0 0 2 2 2 2 pinin/SDK/memA/ protein conserved region Abhydrolase_6 PF12697.2 KKK13505.1 - 3.3e-32 112.2 0.0 4.3e-32 111.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KKK13505.1 - 3.2e-18 66.1 0.1 1.4e-17 64.0 0.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KKK13505.1 - 3.9e-13 49.3 0.0 1.6e-11 44.1 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KKK13505.1 - 0.0018 18.1 0.0 0.0033 17.2 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Ndr PF03096.9 KKK13505.1 - 0.024 13.1 0.0 0.035 12.5 0.0 1.2 1 0 0 1 1 1 0 Ndr family Saccharop_dh PF03435.13 KKK13506.1 - 4.9e-19 68.5 0.0 6.8e-19 68.1 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Cofilin_ADF PF00241.15 KKK13507.1 - 6.9e-17 61.5 0.0 1.2e-08 34.9 0.0 2.1 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein MFS_1 PF07690.11 KKK13508.1 - 2.5e-39 135.0 37.5 2.5e-39 135.0 26.0 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily zf-RING_2 PF13639.1 KKK13509.1 - 6.3e-10 38.7 0.7 6.3e-10 38.7 0.5 3.3 3 0 0 3 3 3 1 Ring finger domain PHD PF00628.24 KKK13509.1 - 6.4e-10 38.5 13.2 1.7e-09 37.2 4.1 2.5 2 0 0 2 2 2 1 PHD-finger zf-C3HC4_2 PF13923.1 KKK13509.1 - 1.2e-06 28.4 0.8 1.2e-06 28.4 0.6 3.1 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KKK13509.1 - 1.7e-06 27.6 0.6 1.7e-06 27.6 0.4 3.2 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KKK13509.1 - 2.4e-06 27.1 0.3 2.4e-06 27.1 0.2 3.2 4 0 0 4 4 4 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KKK13509.1 - 3.1e-06 26.7 0.1 3.1e-06 26.7 0.1 2.8 4 0 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) PHD_2 PF13831.1 KKK13509.1 - 9.7e-06 24.8 1.8 2.1e-05 23.7 1.2 1.6 1 0 0 1 1 1 1 PHD-finger zf-rbx1 PF12678.2 KKK13509.1 - 3.8e-05 23.7 3.7 3.8e-05 23.7 2.6 2.7 2 1 0 2 2 2 1 RING-H2 zinc finger Prok-RING_4 PF14447.1 KKK13509.1 - 0.0012 18.3 0.5 0.0012 18.3 0.4 2.5 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-Apc11 PF12861.2 KKK13509.1 - 0.0035 17.1 0.0 0.0035 17.1 0.0 1.8 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 KKK13509.1 - 0.028 14.1 2.2 0.095 12.4 0.5 2.4 1 1 1 2 2 2 0 RING-type zinc-finger zf-RING_4 PF14570.1 KKK13509.1 - 0.07 12.7 0.1 0.07 12.7 0.1 2.4 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Rtf2 PF04641.7 KKK13509.1 - 0.096 11.8 0.0 0.096 11.8 0.0 1.8 2 0 0 2 2 2 0 Rtf2 RING-finger DUF2051 PF09738.4 KKK13509.1 - 0.26 10.5 1.8 0.48 9.6 1.2 1.3 1 0 0 1 1 1 0 Double stranded RNA binding protein (DUF2051) DZR PF12773.2 KKK13509.1 - 0.48 10.2 4.9 10 5.9 1.8 2.7 2 1 1 3 3 3 0 Double zinc ribbon zf-C2HC_2 PF13913.1 KKK13509.1 - 0.83 9.3 4.6 0.65 9.7 0.3 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type RINGv PF12906.2 KKK13509.1 - 8.8 6.4 10.7 0.54 10.3 1.1 2.5 2 0 0 2 2 2 0 RING-variant domain zf-RING-like PF08746.6 KKK13509.1 - 9.1 6.3 12.9 11 6.0 0.6 2.4 2 0 0 2 2 2 0 RING-like domain Prok-RING_1 PF14446.1 KKK13509.1 - 9.6 6.0 8.7 1.3 8.8 0.8 2.7 2 1 0 2 2 2 0 Prokaryotic RING finger family 1 Lectin_leg-like PF03388.8 KKK13510.1 - 8.2e-27 93.8 0.0 1.3e-26 93.1 0.0 1.2 1 0 0 1 1 1 1 Legume-like lectin family IncA PF04156.9 KKK13510.1 - 0.029 13.9 7.2 0.054 13.0 5.0 1.4 1 0 0 1 1 1 0 IncA protein EMP24_GP25L PF01105.19 KKK13510.1 - 0.061 13.0 2.3 0.13 11.9 1.6 1.6 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD FAM196 PF15265.1 KKK13510.1 - 0.065 12.4 5.4 0.083 12.1 3.7 1.1 1 0 0 1 1 1 0 FAM196 family FolB PF02152.13 KKK13510.1 - 0.09 12.9 0.2 5.3 7.2 0.0 2.3 1 1 1 2 2 2 0 Dihydroneopterin aldolase FUSC PF04632.7 KKK13510.1 - 0.19 10.1 2.0 0.25 9.7 1.4 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF4349 PF14257.1 KKK13510.1 - 0.7 9.0 7.8 12 5.0 5.3 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4349) Seryl_tRNA_N PF02403.17 KKK13510.1 - 2.1 8.3 6.8 4.1 7.4 4.7 1.5 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain PHD PF00628.24 KKK13511.1 - 8.2e-20 70.2 19.0 2.1e-12 46.5 4.8 2.6 2 1 0 2 2 2 2 PHD-finger zf-HC5HC2H PF13771.1 KKK13511.1 - 0.0021 18.1 4.7 0.69 10.0 0.2 2.4 2 0 0 2 2 2 2 PHD-like zinc-binding domain C1_1 PF00130.17 KKK13511.1 - 0.024 14.3 11.9 0.073 12.8 1.5 2.4 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-PHD-like PF15446.1 KKK13511.1 - 0.064 12.5 11.1 0.44 9.8 1.7 2.8 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain PHD_2 PF13831.1 KKK13511.1 - 0.29 10.4 19.2 0.1 11.9 1.2 3.6 4 0 0 4 4 4 0 PHD-finger Prok-RING_1 PF14446.1 KKK13511.1 - 0.76 9.5 12.8 0.13 12.0 2.5 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-HC5HC2H_2 PF13832.1 KKK13511.1 - 3.2 7.7 7.0 17 5.4 0.4 2.4 2 0 0 2 2 2 0 PHD-zinc-finger like domain Alg6_Alg8 PF03155.10 KKK13512.1 - 2.2e-139 465.3 32.0 2.7e-139 465.0 22.2 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family SNF5 PF04855.7 KKK13513.1 - 1.5e-80 270.1 0.5 2.4e-80 269.5 0.4 1.3 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 DUF4648 PF15505.1 KKK13513.1 - 0.12 12.5 4.8 0.037 14.2 0.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4648) HEAT_2 PF13646.1 KKK13514.1 - 2.1e-08 34.3 7.7 3.1e-05 24.1 1.0 6.0 5 2 2 7 7 7 2 HEAT repeats RIX1 PF08167.7 KKK13514.1 - 3.5e-05 23.5 0.3 0.45 10.1 0.0 4.9 6 0 0 6 6 6 2 rRNA processing/ribosome biogenesis HEAT PF02985.17 KKK13514.1 - 9.8e-05 22.1 13.4 0.028 14.5 0.0 6.5 7 0 0 7 7 7 2 HEAT repeat HEAT_EZ PF13513.1 KKK13514.1 - 0.00016 22.0 6.9 0.0096 16.3 0.1 4.5 4 0 0 4 4 4 1 HEAT-like repeat Nipped-B_C PF12830.2 KKK13514.1 - 0.024 14.2 0.1 1.5 8.4 0.0 3.5 3 0 0 3 3 3 0 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.2 KKK13514.1 - 0.035 14.0 1.3 4.4 7.3 0.0 4.0 4 0 0 4 4 4 0 HEAT repeat associated with sister chromatid cohesion Peptidase_M24 PF00557.19 KKK13515.1 - 5.1e-14 52.3 0.0 7.5e-14 51.8 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Exo_endo_phos PF03372.18 KKK13516.1 - 3.6e-06 27.1 0.5 1.6e-05 24.9 0.4 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family FAD_binding_3 PF01494.14 KKK13518.1 - 1.2e-17 64.0 0.1 1e-06 28.0 0.0 3.1 3 0 0 3 3 3 3 FAD binding domain NAD_binding_8 PF13450.1 KKK13518.1 - 0.00041 20.3 0.1 0.001 19.0 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KKK13518.1 - 0.00073 18.5 0.3 0.015 14.2 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Amino_oxidase PF01593.19 KKK13518.1 - 0.0041 16.2 0.0 0.42 9.6 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.19 KKK13518.1 - 0.0072 15.2 0.1 0.013 14.3 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 KKK13518.1 - 0.023 13.7 0.1 0.049 12.7 0.0 1.5 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.7 KKK13518.1 - 0.034 13.0 0.9 4.2 6.2 0.1 2.7 3 0 0 3 3 3 0 Lycopene cyclase protein Pyr_redox PF00070.22 KKK13518.1 - 0.05 13.9 0.6 0.28 11.5 0.1 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KKK13518.1 - 0.052 13.4 0.1 0.11 12.3 0.1 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase COX15-CtaA PF02628.10 KKK13520.1 - 1.4e-97 326.2 5.8 1.7e-97 325.9 4.0 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein zf-C3HC PF07967.8 KKK13521.1 - 4.1e-41 139.8 0.0 3.5e-38 130.4 0.0 2.2 2 0 0 2 2 2 2 C3HC zinc finger-like Rsm1 PF08600.5 KKK13521.1 - 5.5e-36 122.3 0.1 1.8e-32 111.0 0.0 2.5 2 0 0 2 2 2 2 Rsm1-like DM PF00751.13 KKK13521.1 - 0.13 11.8 0.2 3.9 7.0 0.1 2.3 2 0 0 2 2 2 0 DM DNA binding domain Pox_MCEL PF03291.11 KKK13522.1 - 3.6e-59 200.2 0.0 8.9e-55 185.8 0.0 3.7 1 1 0 1 1 1 1 mRNA capping enzyme Methyltransf_12 PF08242.7 KKK13522.1 - 5.1e-07 30.0 0.0 5.3e-06 26.8 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KKK13522.1 - 1.9e-06 28.2 0.0 0.042 14.3 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_18 PF12847.2 KKK13522.1 - 1.3e-05 25.7 0.0 2.9e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KKK13522.1 - 2.5e-05 24.0 0.0 5.2e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KKK13522.1 - 7.1e-05 22.4 0.0 0.028 14.0 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 KKK13522.1 - 0.018 13.9 0.0 0.03 13.3 0.0 1.2 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family Methyltransf_25 PF13649.1 KKK13522.1 - 0.035 14.4 0.0 0.14 12.4 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain Ribosomal_60s PF00428.14 KKK13522.1 - 0.12 12.7 5.2 0.053 13.9 0.8 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein p450 PF00067.17 KKK13523.1 - 3.7e-58 197.1 0.0 5.1e-58 196.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 polyprenyl_synt PF00348.12 KKK13523.1 - 4.3e-13 48.6 0.0 7.8e-13 47.8 0.0 1.3 1 0 0 1 1 1 1 Polyprenyl synthetase GST_N_3 PF13417.1 KKK13524.1 - 3.4e-09 36.7 0.0 7.5e-09 35.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KKK13524.1 - 1.1e-07 31.6 0.0 2.2e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KKK13524.1 - 0.00047 19.9 0.4 0.0018 18.1 0.3 2.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Peptidase_M43 PF05572.8 KKK13539.1 - 7.6e-12 45.0 0.2 1.9e-11 43.7 0.1 1.6 1 1 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_2 PF13574.1 KKK13539.1 - 0.005 16.9 0.0 0.0089 16.0 0.0 1.5 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.19 KKK13539.1 - 0.026 14.2 0.0 0.035 13.8 0.0 1.2 1 0 0 1 1 1 0 Matrixin Reprolysin_4 PF13583.1 KKK13539.1 - 0.1 12.1 0.1 0.42 10.1 0.1 1.9 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 KKK13539.1 - 0.13 12.8 0.9 0.62 10.6 0.2 2.3 2 1 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 KKK13539.1 - 0.16 11.8 0.3 0.58 10.0 0.2 1.9 1 1 0 1 1 1 0 Metallo-peptidase family M12 Abhydrolase_6 PF12697.2 KKK13540.1 - 3.6e-24 85.9 0.2 4.6e-24 85.5 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KKK13540.1 - 7.6e-12 45.2 0.2 9.4e-11 41.7 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KKK13540.1 - 2e-07 30.8 0.2 3.5e-07 30.0 0.1 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 KKK13540.1 - 0.00031 21.0 0.0 0.00045 20.5 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_8 PF06259.7 KKK13540.1 - 0.00043 19.8 0.1 0.0012 18.3 0.0 1.8 1 1 1 2 2 2 1 Alpha/beta hydrolase PGAP1 PF07819.8 KKK13540.1 - 0.007 15.9 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein IFT57 PF10498.4 KKK13540.1 - 0.044 12.5 0.1 0.059 12.1 0.1 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 DUF1993 PF09351.5 KKK13542.1 - 9.8e-51 171.8 0.0 1.1e-50 171.7 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) DAGAT PF03982.8 KKK13543.1 - 5.9e-52 176.2 0.1 9.1e-52 175.5 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol acyltransferase UDPGT PF00201.13 KKK13543.1 - 1e-09 37.5 0.0 1.6e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.11 KKK13543.1 - 0.013 15.1 0.0 0.023 14.3 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.1 KKK13543.1 - 0.03 13.5 0.0 0.052 12.7 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 p450 PF00067.17 KKK13544.1 - 2e-58 198.0 0.0 2.6e-58 197.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Zn_clus PF00172.13 KKK13545.1 - 1e-08 34.9 11.1 2.1e-08 33.9 7.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RVT_1 PF00078.22 KKK13545.1 - 4.8e-06 26.0 0.0 1.1e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Pox_A_type_inc PF04508.7 KKK13545.1 - 0.13 12.1 8.7 0.023 14.4 1.2 3.2 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat ELO PF01151.13 KKK13547.1 - 4.2e-60 203.1 19.7 5.3e-60 202.8 13.6 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family ABC_membrane PF00664.18 KKK13548.1 - 9.6e-82 274.4 34.0 2.5e-43 148.4 10.4 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KKK13548.1 - 9.5e-72 239.7 0.0 7.5e-36 123.4 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 KKK13548.1 - 4.6e-14 52.1 0.0 6e-05 22.3 0.0 3.9 4 1 0 4 4 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KKK13548.1 - 5.1e-13 49.6 1.4 0.015 15.2 0.0 4.3 3 1 1 4 4 4 4 AAA domain ABC_ATPase PF09818.4 KKK13548.1 - 2.5e-10 39.5 3.9 4.4e-05 22.2 0.2 2.9 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_16 PF13191.1 KKK13548.1 - 7.3e-09 35.8 0.3 0.0067 16.4 0.1 3.1 2 1 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 KKK13548.1 - 2.6e-08 33.2 0.3 0.0004 19.8 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 KKK13548.1 - 1.5e-07 32.2 0.0 0.029 15.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 KKK13548.1 - 5e-07 29.0 0.1 0.015 14.4 0.0 3.1 3 0 0 3 3 3 2 Protein of unknown function, DUF258 SbcCD_C PF13558.1 KKK13548.1 - 1e-05 25.3 3.8 0.085 12.7 0.2 4.2 3 2 0 3 3 3 2 Putative exonuclease SbcCD, C subunit AAA_25 PF13481.1 KKK13548.1 - 1.1e-05 24.9 4.3 0.18 11.2 0.0 4.7 6 0 0 6 6 6 2 AAA domain AAA_22 PF13401.1 KKK13548.1 - 1.2e-05 25.4 1.6 0.48 10.5 0.1 4.1 2 2 0 2 2 2 2 AAA domain AAA_18 PF13238.1 KKK13548.1 - 8.2e-05 22.9 0.0 0.29 11.4 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 KKK13548.1 - 0.00013 21.8 0.0 0.46 10.3 0.0 3.0 3 0 0 3 3 2 2 AAA domain SRP54 PF00448.17 KKK13548.1 - 0.00043 19.7 0.0 1.3 8.4 0.0 2.9 2 0 0 2 2 2 2 SRP54-type protein, GTPase domain AAA_28 PF13521.1 KKK13548.1 - 0.00071 19.5 0.1 0.16 11.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 KKK13548.1 - 0.0018 17.9 0.1 1.4 8.6 0.0 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_23 PF13476.1 KKK13548.1 - 0.0022 18.3 1.3 0.25 11.6 0.1 2.8 3 0 0 3 3 3 1 AAA domain AAA_5 PF07728.9 KKK13548.1 - 0.0059 16.3 0.1 8.2 6.1 0.0 3.9 3 1 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.1 KKK13548.1 - 0.0069 15.9 6.8 2 7.9 0.1 4.4 4 1 0 4 4 4 1 AAA domain AAA_10 PF12846.2 KKK13548.1 - 0.0077 15.7 4.2 2.1 7.6 0.2 4.3 5 0 0 5 5 4 1 AAA-like domain DUF87 PF01935.12 KKK13548.1 - 0.014 15.2 0.4 3.4 7.4 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF87 MMR_HSR1 PF01926.18 KKK13548.1 - 0.022 14.7 0.0 12 5.8 0.0 2.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase Mg_chelatase PF01078.16 KKK13548.1 - 0.051 12.7 0.0 2.4 7.2 0.0 2.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 KKK13548.1 - 0.057 13.5 0.1 10 6.3 0.0 2.9 2 0 0 2 2 2 0 RNA helicase PRK PF00485.13 KKK13548.1 - 0.073 12.6 0.0 2.5 7.6 0.0 2.5 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family APS_kinase PF01583.15 KKK13548.1 - 0.075 12.6 0.0 4.8 6.8 0.0 2.8 2 0 0 2 2 2 0 Adenylylsulphate kinase Katanin_con80 PF13925.1 KKK13548.1 - 0.081 12.6 0.0 22 4.7 0.0 3.3 3 0 0 3 3 3 0 con80 domain of Katanin AAA_15 PF13175.1 KKK13548.1 - 0.085 11.8 0.0 8.7 5.2 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain G-alpha PF00503.15 KKK13548.1 - 0.089 11.4 0.0 5.4 5.5 0.0 2.3 2 0 0 2 2 2 0 G-protein alpha subunit Rad17 PF03215.10 KKK13548.1 - 0.15 10.7 0.0 1.6 7.3 0.0 2.0 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein ATP-grasp_4 PF13535.1 KKK13549.1 - 2.4e-09 37.1 0.0 4.2e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.9 KKK13549.1 - 3.4e-09 36.7 0.0 1e-08 35.2 0.0 1.8 1 1 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 KKK13549.1 - 9.5e-09 34.4 0.0 7.2e-05 21.6 0.0 2.1 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Glyco_hydro_16 PF00722.16 KKK13551.1 - 1.1e-09 37.8 0.4 2.2e-09 36.8 0.1 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 NIP_1 PF08995.5 KKK13551.1 - 0.0089 16.1 0.3 0.017 15.2 0.2 1.5 1 0 0 1 1 1 1 Necrosis inducing protein-1 COesterase PF00135.23 KKK13552.1 - 2.5e-13 49.6 0.0 5.5e-13 48.4 0.0 1.5 1 1 0 1 1 1 1 Carboxylesterase family COesterase PF00135.23 KKK13553.1 - 2.1e-40 138.9 0.0 2.6e-40 138.6 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KKK13553.1 - 0.00035 20.2 0.1 0.0006 19.4 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Clr5 PF14420.1 KKK13554.1 - 1.3e-11 44.2 0.9 2.1e-11 43.5 0.6 1.3 1 0 0 1 1 1 1 Clr5 domain Glyco_hydro_7 PF00840.15 KKK13555.1 - 5.4e-129 430.3 21.5 5.4e-129 430.3 14.9 2.8 2 1 0 2 2 2 1 Glycosyl hydrolase family 7 Fer4_20 PF14691.1 KKK13555.1 - 2.3 7.8 5.8 7.6 6.2 0.5 2.3 2 0 0 2 2 2 0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Tyrosinase PF00264.15 KKK13556.1 - 4.1e-30 105.6 9.9 5.5e-30 105.1 6.8 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase DPPIV_N PF00930.16 KKK13557.1 - 2.4e-06 26.3 0.1 5.5e-06 25.1 0.0 1.6 2 0 0 2 2 2 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region DPPIV_N PF00930.16 KKK13558.1 - 9.1e-13 47.5 2.1 9.8e-09 34.2 0.6 2.1 2 0 0 2 2 2 2 Dipeptidyl peptidase IV (DPP IV) N-terminal region DUF3941 PF13081.1 KKK13558.1 - 0.097 12.6 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3941) MFS_1 PF07690.11 KKK13559.1 - 2.6e-30 105.3 28.7 2.6e-30 105.3 19.9 1.8 2 1 1 3 3 3 1 Major Facilitator Superfamily Beta-lactamase PF00144.19 KKK13560.1 - 4.6e-40 137.6 0.0 1.2e-39 136.2 0.0 1.6 1 1 0 1 1 1 1 Beta-lactamase Abhydrolase_3 PF07859.8 KKK13561.1 - 2.3e-24 86.1 0.0 3e-24 85.7 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 KKK13561.1 - 2.9e-18 65.6 0.0 4e-18 65.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 KKK13561.1 - 7.6e-06 25.7 0.1 1.3e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KKK13561.1 - 0.00047 19.4 0.0 0.77 8.9 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Pro-kuma_activ PF09286.6 KKK13562.1 - 7e-42 142.8 0.0 1.4e-41 141.8 0.0 1.5 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 KKK13562.1 - 2e-05 23.8 0.1 5.3e-05 22.5 0.1 1.6 2 0 0 2 2 2 1 Subtilase family DUF1798 PF08807.5 KKK13562.1 - 0.11 12.1 0.3 0.23 11.1 0.2 1.4 1 0 0 1 1 1 0 Bacterial domain of unknown function (DUF1798) Ribosomal_S20p PF01649.13 KKK13562.1 - 0.15 12.5 3.0 0.24 11.7 2.1 1.3 1 0 0 1 1 1 0 Ribosomal protein S20 dCMP_cyt_deam_1 PF00383.17 KKK13563.1 - 1.3e-10 40.8 0.0 2.2e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Glyco_hydro_28 PF00295.12 KKK13564.1 - 1.9e-109 365.6 18.9 2.1e-109 365.4 13.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.1 KKK13564.1 - 0.00011 21.9 24.7 0.097 12.4 8.3 3.2 1 1 1 3 3 3 3 Right handed beta helix region V-ATPase_H_N PF03224.9 KKK13589.1 - 8.1e-85 284.6 0.0 1.2e-84 284.1 0.0 1.2 1 0 0 1 1 1 1 V-ATPase subunit H V-ATPase_H_C PF11698.3 KKK13589.1 - 2.6e-40 137.0 0.0 8.6e-40 135.3 0.0 1.9 2 0 0 2 2 2 1 V-ATPase subunit H HCaRG PF07258.9 KKK13589.1 - 0.016 14.7 0.1 0.08 12.4 0.0 2.2 2 1 0 2 2 2 0 HCaRG protein SPO22 PF08631.5 KKK13589.1 - 0.061 12.3 0.0 0.2 10.7 0.0 1.7 2 0 0 2 2 2 0 Meiosis protein SPO22/ZIP4 like HEAT_EZ PF13513.1 KKK13589.1 - 0.4 11.2 2.4 8 7.0 0.0 3.8 3 2 1 4 4 4 0 HEAT-like repeat TMF_TATA_bd PF12325.3 KKK13590.1 - 2.9e-44 149.6 11.5 2.9e-44 149.6 7.9 6.0 3 2 2 5 5 5 1 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.3 KKK13590.1 - 2.4e-17 62.4 12.9 2.4e-17 62.4 9.0 9.1 6 3 2 9 9 9 2 TATA element modulatory factor 1 DNA binding Laminin_II PF06009.7 KKK13590.1 - 3.7 7.3 54.0 0.13 12.0 6.4 5.6 2 2 2 5 5 5 0 Laminin Domain II NPV_P10 PF05531.7 KKK13590.1 - 4.4 7.6 24.8 0.44 10.8 3.4 5.9 5 2 0 5 5 5 0 Nucleopolyhedrovirus P10 protein Filament PF00038.16 KKK13590.1 - 5.6 6.3 76.3 0.52 9.7 4.6 3.7 2 1 1 3 3 3 0 Intermediate filament protein Reo_sigmaC PF04582.7 KKK13590.1 - 6 5.9 23.3 0.051 12.7 0.9 4.2 2 1 1 4 4 4 0 Reovirus sigma C capsid protein AAA PF00004.24 KKK13591.1 - 9e-14 51.7 0.0 1.7e-13 50.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KKK13591.1 - 1.5e-10 41.3 0.0 4.6e-10 39.7 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KKK13591.1 - 8.8e-09 35.6 0.0 3.4e-08 33.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain BAH PF01426.13 KKK13591.1 - 7.2e-06 25.7 0.0 1.7e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 BAH domain AAA_17 PF13207.1 KKK13591.1 - 2.4e-05 25.1 0.0 0.00033 21.4 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.1 KKK13591.1 - 0.0012 18.5 2.3 0.0033 17.1 0.2 2.6 2 0 0 2 2 2 1 Part of AAA domain AAA_28 PF13521.1 KKK13591.1 - 0.0018 18.2 0.0 0.0042 17.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 KKK13591.1 - 0.0033 17.0 0.0 0.012 15.2 0.0 2.0 2 1 0 2 2 2 1 NACHT domain DUF2075 PF09848.4 KKK13591.1 - 0.0094 14.9 0.0 0.022 13.7 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_11 PF13086.1 KKK13591.1 - 0.017 14.6 0.0 0.033 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_32 PF13654.1 KKK13591.1 - 0.018 13.6 0.0 0.033 12.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 KKK13591.1 - 0.028 14.7 0.0 0.072 13.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 KKK13591.1 - 0.031 14.1 0.0 0.19 11.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain Zot PF05707.7 KKK13591.1 - 0.061 12.7 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) PIF1 PF05970.9 KKK13591.1 - 0.067 12.1 0.0 0.16 10.9 0.0 1.5 1 0 0 1 1 1 0 PIF1-like helicase Arch_ATPase PF01637.13 KKK13591.1 - 0.071 12.7 0.0 0.8 9.3 0.0 2.2 1 1 0 1 1 1 0 Archaeal ATPase KH_3 PF13014.1 KKK13592.1 - 0.17 11.5 0.0 2.5 7.8 0.0 2.5 2 0 0 2 2 2 0 KH domain Ank_2 PF12796.2 KKK13593.1 - 2.3e-36 124.0 4.1 1.2e-16 60.7 0.5 3.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KKK13593.1 - 6.6e-31 105.6 2.9 2.3e-09 37.2 0.1 4.6 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.25 KKK13593.1 - 2.2e-30 102.9 2.3 3.4e-06 26.5 0.0 6.2 6 0 0 6 6 6 5 Ankyrin repeat Ank_4 PF13637.1 KKK13593.1 - 1.3e-24 86.0 1.1 1.3e-07 31.9 0.1 5.3 2 1 4 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 KKK13593.1 - 1.4e-23 80.5 0.3 8.3e-05 22.4 0.0 6.3 7 0 0 7 7 7 5 Ankyrin repeat WD40 PF00400.27 KKK13594.1 - 6.2e-54 178.0 8.5 2e-09 36.9 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 KKK13594.1 - 0.0055 14.8 3.8 4 5.4 0.6 4.4 1 1 2 3 3 3 1 Nucleoporin Nup120/160 Prefoldin PF02996.12 KKK13595.1 - 1.1e-12 47.6 0.8 7e-12 45.0 0.6 2.0 1 1 0 1 1 1 1 Prefoldin subunit Glu-tRNAGln PF02686.10 KKK13595.1 - 0.0091 15.7 0.0 0.026 14.3 0.0 1.7 2 0 0 2 2 2 1 Glu-tRNAGln amidotransferase C subunit TMF_TATA_bd PF12325.3 KKK13595.1 - 0.053 13.2 0.4 2.4 7.9 0.0 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DASH_Hsk3 PF08227.6 KKK13595.1 - 0.079 13.1 3.0 0.16 12.1 0.1 2.2 2 0 0 2 2 2 0 DASH complex subunit Hsk3 like DUF883 PF05957.8 KKK13595.1 - 0.15 12.5 1.2 15 6.0 0.4 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Dabb PF07876.7 KKK13596.1 - 7e-24 84.0 0.0 7.9e-24 83.9 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Fungal_trans_2 PF11951.3 KKK13597.1 - 2.8e-58 197.3 1.5 4.2e-58 196.7 1.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Hormone_recep PF00104.25 KKK13597.1 - 0.031 13.3 0.4 0.061 12.4 0.3 1.5 1 0 0 1 1 1 0 Ligand-binding domain of nuclear hormone receptor ATP-synt_10 PF05176.9 KKK13607.1 - 9.3e-95 316.6 0.0 1.3e-94 316.2 0.0 1.2 1 0 0 1 1 1 1 ATP10 protein zf-BED PF02892.10 KKK13608.1 - 0.0048 16.6 0.4 0.0048 16.6 0.3 1.8 2 0 0 2 2 2 1 BED zinc finger Zn_clus PF00172.13 KKK13608.1 - 0.015 15.2 6.9 0.035 14.0 4.8 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DNA_pol_B_palm PF14792.1 KKK13609.1 - 3.8e-31 107.4 0.0 7.5e-31 106.4 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.1 KKK13609.1 - 9.4e-21 73.2 0.0 2.3e-20 72.0 0.0 1.7 2 0 0 2 2 2 1 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.4 KKK13609.1 - 1.5e-19 69.2 0.2 1.2e-18 66.4 0.1 2.4 2 0 0 2 2 2 1 Fingers domain of DNA polymerase lambda HHH_8 PF14716.1 KKK13609.1 - 3.6e-17 62.2 0.1 8.1e-17 61.1 0.1 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain BRCT PF00533.21 KKK13609.1 - 0.00064 19.8 0.0 0.0012 18.9 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain NTP_transf_2 PF01909.18 KKK13609.1 - 0.015 15.6 0.0 0.056 13.7 0.0 1.9 2 0 0 2 2 2 0 Nucleotidyltransferase domain CcdA PF07362.7 KKK13609.1 - 0.02 14.7 0.2 0.045 13.6 0.2 1.6 1 0 0 1 1 1 0 Post-segregation antitoxin CcdA HHH PF00633.18 KKK13609.1 - 0.15 11.8 0.7 0.47 10.2 0.1 2.1 2 0 0 2 2 2 0 Helix-hairpin-helix motif DENN PF02141.16 KKK13622.1 - 4.3e-56 189.5 0.1 7.3e-56 188.8 0.1 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain dDENN PF03455.14 KKK13622.1 - 9.7e-19 67.2 0.7 9.7e-19 67.2 0.5 1.9 2 0 0 2 2 2 1 dDENN domain uDENN PF03456.13 KKK13622.1 - 9.2e-18 63.9 0.0 2e-17 62.8 0.0 1.6 1 0 0 1 1 1 1 uDENN domain C1_3 PF07649.7 KKK13622.1 - 0.0018 18.2 3.8 0.0038 17.2 2.6 1.6 1 0 0 1 1 1 1 C1-like domain C1_1 PF00130.17 KKK13622.1 - 0.0035 17.0 10.6 0.0068 16.1 7.4 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.11 KKK13622.1 - 0.0066 16.5 5.8 0.016 15.3 4.0 1.6 1 0 0 1 1 1 1 C1 domain SPA PF08616.5 KKK13622.1 - 0.076 12.7 0.1 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Stabilization of polarity axis PHD PF00628.24 KKK13622.1 - 0.14 11.8 9.4 0.035 13.7 3.9 2.0 1 1 1 2 2 2 0 PHD-finger Prok-RING_1 PF14446.1 KKK13622.1 - 4.4 7.1 13.4 0.63 9.8 5.8 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 DHquinase_I PF01487.10 KKK13623.1 - 6.6e-43 146.9 0.0 1.3e-42 145.9 0.0 1.5 1 0 0 1 1 1 1 Type I 3-dehydroquinase Fungal_trans PF04082.13 KKK13623.1 - 7e-20 70.9 0.0 1.2e-19 70.1 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK13623.1 - 0.00014 21.6 17.5 0.00014 21.6 12.1 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3632 PF12311.3 KKK13623.1 - 0.0013 18.6 0.1 0.034 13.9 0.0 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF3632) Clusterin PF01093.12 KKK13623.1 - 0.73 8.5 0.8 1.2 7.9 0.5 1.2 1 0 0 1 1 1 0 Clusterin BRO1 PF03097.13 KKK13624.1 - 2.8e-109 365.3 2.6 4.4e-109 364.6 0.0 2.5 2 1 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 KKK13624.1 - 1.3e-81 273.7 14.1 2.4e-81 272.9 9.8 1.4 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV Mito_carr PF00153.22 KKK13625.1 - 6.9e-45 150.6 3.0 2.2e-16 59.3 0.0 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein Thiolase_C PF02803.13 KKK13626.1 - 2.7e-11 42.9 0.5 7.4e-11 41.5 0.3 1.8 1 1 0 1 1 1 1 Thiolase, C-terminal domain ACP_syn_III PF08545.5 KKK13626.1 - 2e-08 33.7 0.2 2.7e-06 26.9 0.1 2.7 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thiolase_N PF00108.18 KKK13626.1 - 6.4e-07 28.6 0.7 1.1e-05 24.6 0.0 2.7 3 0 0 3 3 3 1 Thiolase, N-terminal domain ketoacyl-synt PF00109.21 KKK13626.1 - 8.2e-05 22.2 0.1 0.00015 21.3 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain SpoVAD PF07451.6 KKK13626.1 - 0.023 13.1 0.1 0.051 12.0 0.1 1.5 1 0 0 1 1 1 0 Stage V sporulation protein AD (SpoVAD) SMN PF06003.7 KKK13627.1 - 3.2e-06 26.4 7.3 0.00037 19.6 1.8 2.4 1 1 1 2 2 2 2 Survival motor neuron protein (SMN) DUF2890 PF11081.3 KKK13627.1 - 0.088 12.8 2.2 0.093 12.7 1.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) CHD5 PF04420.9 KKK13628.1 - 1.4e-61 206.8 3.0 1.8e-61 206.5 2.1 1.1 1 0 0 1 1 1 1 CHD5-like protein mRNA_cap_C PF03919.10 KKK13628.1 - 0.1 12.8 0.7 0.17 12.2 0.5 1.3 1 0 0 1 1 1 0 mRNA capping enzyme, C-terminal domain DUF2929 PF11151.3 KKK13628.1 - 1.5 8.9 7.0 1.8 8.7 1.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2929) PPTA PF01239.17 KKK13629.1 - 0.037 13.3 3.4 0.52 9.7 0.3 2.6 2 0 0 2 2 2 0 Protein prenyltransferase alpha subunit repeat RRM_1 PF00076.17 KKK13630.1 - 7.5e-14 51.1 0.0 1.5e-13 50.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KKK13630.1 - 3.6e-10 39.6 0.0 6.7e-10 38.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KKK13630.1 - 3.3e-09 36.4 0.1 6.5e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SOG2 PF10428.4 KKK13630.1 - 4.1 5.9 16.7 0.46 9.0 0.2 2.1 2 0 0 2 2 2 0 RAM signalling pathway protein ADH_N PF08240.7 KKK13631.1 - 5e-21 74.5 0.5 8e-21 73.8 0.4 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KKK13631.1 - 5.7e-17 61.4 0.1 9.8e-17 60.7 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_7 PF13241.1 KKK13631.1 - 0.0004 20.6 0.0 0.00083 19.5 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding ADH_N_assoc PF13823.1 KKK13631.1 - 0.0054 16.3 0.2 0.012 15.2 0.2 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated FAD_binding_3 PF01494.14 KKK13631.1 - 0.0073 15.4 0.3 0.01 14.9 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 KKK13631.1 - 0.02 14.9 0.1 0.03 14.3 0.1 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KKK13631.1 - 0.034 13.0 0.3 0.052 12.4 0.2 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KKK13631.1 - 0.059 13.2 0.2 0.088 12.6 0.2 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF3431 PF11913.3 KKK13646.1 - 4.1e-90 301.1 0.3 6e-90 300.6 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) CoaE PF01121.15 KKK13646.1 - 1.7e-39 135.1 0.0 2.9e-39 134.3 0.0 1.3 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_17 PF13207.1 KKK13646.1 - 0.0037 18.0 0.2 0.019 15.7 0.1 2.2 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KKK13646.1 - 0.14 12.5 0.2 0.69 10.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain zf-CHCC PF10276.4 KKK13647.1 - 1.7e-15 56.5 1.4 2.6e-15 55.9 1.0 1.3 1 0 0 1 1 1 1 Zinc-finger domain COX5B PF01215.14 KKK13647.1 - 0.11 12.1 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase subunit Vb UPF0047 PF01894.12 KKK13648.1 - 3.3e-40 136.5 0.0 3.7e-40 136.4 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 DUF1556 PF07590.6 KKK13649.1 - 0.13 12.4 0.9 0.16 12.2 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1556) MPP6 PF10175.4 KKK13650.1 - 0.71 10.2 0.1 0.71 10.2 0.1 2.6 2 1 2 4 4 4 0 M-phase phosphoprotein 6 PBP1_TM PF14812.1 KKK13650.1 - 1.9 8.8 9.0 4.1 7.7 6.0 1.8 1 1 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal TFIIF_alpha PF05793.7 KKK13650.1 - 3.2 6.0 16.1 0.011 14.0 2.8 2.0 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) RNA_pol_Rpc4 PF05132.9 KKK13650.1 - 4.4 7.2 7.5 2.1 8.3 3.1 2.0 2 2 0 2 2 2 0 RNA polymerase III RPC4 HLH PF00010.21 KKK13657.1 - 7.3e-07 28.7 0.0 1.5e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Cation_ATPase_C PF00689.16 KKK13658.1 - 0.0002 20.9 0.0 0.00041 19.9 0.0 1.5 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus CENP-Q PF13094.1 KKK13659.1 - 7.6e-42 143.0 8.8 7.6e-42 143.0 6.1 1.5 2 0 0 2 2 2 1 CENP-Q, a CENPA-CAD centromere complex subunit DUF904 PF06005.7 KKK13659.1 - 0.016 15.4 6.4 0.016 15.4 4.5 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF904) DUF3333 PF11812.3 KKK13659.1 - 0.036 14.0 0.6 0.072 13.0 0.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3333) TBPIP PF07106.8 KKK13659.1 - 0.22 11.0 10.1 1.1 8.8 0.0 3.0 3 1 0 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Ribonuclease_3 PF00636.21 KKK13664.1 - 2.8e-42 143.7 0.0 4.8e-20 72.1 0.0 3.3 3 0 0 3 3 3 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 KKK13664.1 - 1.5e-23 83.1 0.0 1.2e-11 44.6 0.0 3.9 2 2 0 2 2 2 2 Ribonuclease-III-like Dicer_dimer PF03368.9 KKK13664.1 - 1.2e-22 79.4 0.0 3e-21 75.0 0.0 2.8 2 0 0 2 2 2 1 Dicer dimerisation domain Helicase_C PF00271.26 KKK13664.1 - 5e-14 51.9 0.0 1.2e-13 50.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KKK13664.1 - 3.3e-11 43.3 0.1 9.3e-11 41.8 0.1 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 KKK13664.1 - 3.3e-09 36.4 0.0 1.5e-08 34.3 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase dsrm PF00035.20 KKK13664.1 - 0.00026 21.4 0.0 0.84 10.2 0.0 2.8 2 0 0 2 2 2 2 Double-stranded RNA binding motif DUF2075 PF09848.4 KKK13664.1 - 0.015 14.2 0.0 0.029 13.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) TAP42 PF04177.7 KKK13665.1 - 3.2e-109 364.9 5.7 3.6e-109 364.8 3.9 1.0 1 0 0 1 1 1 1 TAP42-like family Svf1 PF08622.5 KKK13666.1 - 2.5e-108 361.9 0.0 2.8e-108 361.7 0.0 1.0 1 0 0 1 1 1 1 Svf1-like CrtC PF07143.6 KKK13666.1 - 0.0029 16.9 0.1 0.0033 16.7 0.1 1.2 1 0 0 1 1 1 1 Hydroxyneurosporene synthase (CrtC) DHC_N1 PF08385.7 KKK13667.1 - 4.6e-189 629.5 12.6 4.6e-189 629.5 8.7 5.1 7 0 0 7 7 6 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.8 KKK13667.1 - 5.2e-130 433.6 7.4 5.2e-130 433.6 5.1 4.8 5 0 0 5 5 4 1 Dynein heavy chain, N-terminal region 2 Dynein_heavy PF03028.10 KKK13667.1 - 2.7e-108 362.8 0.1 1.1e-107 360.9 0.0 2.0 2 0 0 2 2 2 1 Dynein heavy chain and region D6 of dynein motor AAA_6 PF12774.2 KKK13667.1 - 8.2e-80 267.6 0.0 3.2e-79 265.6 0.0 2.1 2 0 0 2 2 1 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_9 PF12781.2 KKK13667.1 - 1.5e-43 148.2 0.1 7.7e-43 145.9 0.0 2.3 2 0 0 2 2 2 1 ATP-binding dynein motor region D5 AAA_8 PF12780.2 KKK13667.1 - 1.9e-42 145.1 0.2 2.3e-41 141.5 0.1 2.5 1 1 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_5 PF07728.9 KKK13667.1 - 5.8e-32 110.3 0.0 6.8e-11 42.0 0.0 5.7 4 1 0 4 4 4 4 AAA domain (dynein-related subfamily) MT PF12777.2 KKK13667.1 - 9e-31 106.8 11.1 5.2e-28 97.7 7.7 2.4 1 1 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_7 PF12775.2 KKK13667.1 - 4e-19 68.7 0.1 2.6e-18 66.0 0.0 2.4 3 0 0 3 3 3 1 P-loop containing dynein motor region D3 AAA PF00004.24 KKK13667.1 - 1.9e-15 57.2 0.0 8.7e-05 22.7 0.0 5.4 5 0 0 5 5 4 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KKK13667.1 - 3e-15 56.5 0.1 0.0098 16.0 0.0 6.5 5 0 0 5 5 5 3 AAA domain AAA_18 PF13238.1 KKK13667.1 - 7.1e-11 42.5 0.2 0.029 14.6 0.0 5.7 5 0 0 5 5 5 2 AAA domain AAA_33 PF13671.1 KKK13667.1 - 2e-10 40.6 0.3 0.31 10.8 0.0 5.7 5 0 0 5 5 4 3 AAA domain AAA_17 PF13207.1 KKK13667.1 - 2.9e-10 41.0 0.0 0.04 14.7 0.0 6.1 5 0 0 5 5 5 2 AAA domain T2SE PF00437.15 KKK13667.1 - 7.3e-08 31.6 0.0 0.016 14.1 0.0 3.9 4 0 0 4 4 4 2 Type II/IV secretion system protein ABC_tran PF00005.22 KKK13667.1 - 1.8e-06 28.2 0.2 0.43 10.8 0.0 5.5 4 0 0 4 4 3 2 ABC transporter AAA_29 PF13555.1 KKK13667.1 - 5.2e-06 25.8 0.0 1.4 8.4 0.0 3.7 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_19 PF13245.1 KKK13667.1 - 2.6e-05 23.8 0.1 0.42 10.3 0.0 4.5 4 0 0 4 4 4 1 Part of AAA domain Mg_chelatase PF01078.16 KKK13667.1 - 8.2e-05 21.8 0.9 0.43 9.6 0.0 3.7 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 KKK13667.1 - 0.00023 20.3 2.2 0.46 9.5 0.0 4.3 4 0 0 4 4 3 2 Zeta toxin DUF258 PF03193.11 KKK13667.1 - 0.00091 18.4 0.0 4.2 6.5 0.0 3.7 3 0 0 3 3 3 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 KKK13667.1 - 0.0013 18.7 21.8 0.14 12.0 0.1 8.7 8 3 1 10 10 9 1 AAA ATPase domain FtsK_SpoIIIE PF01580.13 KKK13667.1 - 0.0013 18.2 0.4 16 4.8 0.0 4.4 4 0 0 4 4 3 0 FtsK/SpoIIIE family RNA_helicase PF00910.17 KKK13667.1 - 0.0036 17.4 0.2 16 5.7 0.0 5.0 5 0 0 5 5 5 0 RNA helicase 3-alpha PF03475.9 KKK13667.1 - 0.0047 16.6 0.2 0.023 14.4 0.1 2.3 1 0 0 1 1 1 1 3-alpha domain MobB PF03205.9 KKK13667.1 - 0.0083 15.8 0.3 11 5.6 0.0 3.5 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.1 KKK13667.1 - 0.012 15.0 0.6 0.75 9.1 0.0 3.6 4 0 0 4 4 3 0 AAA domain ERM PF00769.14 KKK13667.1 - 0.38 10.2 23.0 0.53 9.7 2.6 3.0 2 0 0 2 2 2 0 Ezrin/radixin/moesin family PduV-EutP PF10662.4 KKK13667.1 - 0.66 9.4 5.3 6.9 6.1 0.1 4.2 5 0 0 5 5 4 0 Ethanolamine utilisation - propanediol utilisation Porphobil_deam PF01379.15 KKK13668.1 - 1.2e-76 256.3 0.0 1.5e-76 256.0 0.0 1.1 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.10 KKK13668.1 - 1.6e-17 63.3 0.0 2.8e-17 62.5 0.0 1.4 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain Ribosomal_L23 PF00276.15 KKK13669.1 - 1.2e-14 53.9 0.0 2e-14 53.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L23 Lon_C PF05362.8 KKK13670.1 - 2.6e-46 157.5 0.4 6e-43 146.5 0.1 3.2 2 1 1 3 3 3 2 Lon protease (S16) C-terminal proteolytic domain LON PF02190.11 KKK13670.1 - 5.8e-28 97.9 0.3 1.2e-27 96.9 0.0 1.6 2 0 0 2 2 2 1 ATP-dependent protease La (LON) domain AAA PF00004.24 KKK13670.1 - 1.9e-23 83.0 0.0 1.1e-22 80.5 0.0 2.4 3 0 0 3 3 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KKK13670.1 - 5.8e-08 32.5 0.0 2e-07 30.8 0.0 2.0 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KKK13670.1 - 1.1e-06 28.7 0.7 6.3e-06 26.2 0.0 2.6 3 0 0 3 3 2 1 AAA ATPase domain AAA_17 PF13207.1 KKK13670.1 - 3.5e-05 24.6 0.0 0.00016 22.4 0.0 2.2 2 0 0 2 2 1 1 AAA domain AAA_19 PF13245.1 KKK13670.1 - 5.1e-05 22.9 0.1 0.00013 21.6 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_3 PF07726.6 KKK13670.1 - 5.1e-05 22.8 0.0 0.00017 21.2 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 KKK13670.1 - 0.00014 20.9 0.1 0.0017 17.4 0.0 2.2 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus TIP49 PF06068.8 KKK13670.1 - 0.00029 19.6 0.1 0.0026 16.5 0.0 2.1 2 0 0 2 2 2 1 TIP49 C-terminus AAA_2 PF07724.9 KKK13670.1 - 0.00057 19.8 0.0 0.002 18.0 0.0 2.0 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 KKK13670.1 - 0.0014 18.7 0.1 0.011 15.8 0.0 2.7 2 1 0 2 2 1 1 AAA domain AAA_33 PF13671.1 KKK13670.1 - 0.0019 18.0 0.0 0.0061 16.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KKK13670.1 - 0.002 17.2 0.0 0.0046 16.0 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin IstB_IS21 PF01695.12 KKK13670.1 - 0.0051 16.2 0.0 0.012 15.0 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.1 KKK13670.1 - 0.0092 15.8 0.0 0.023 14.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 KKK13670.1 - 0.017 14.5 0.0 0.047 13.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain UPF0079 PF02367.12 KKK13670.1 - 0.02 14.5 0.0 0.049 13.2 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_18 PF13238.1 KKK13670.1 - 0.024 14.9 0.0 0.071 13.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 KKK13670.1 - 0.029 13.5 0.1 0.093 11.8 0.0 1.8 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_30 PF13604.1 KKK13670.1 - 0.04 13.4 0.0 0.077 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 KKK13670.1 - 0.048 13.3 0.1 0.18 11.4 0.0 2.0 2 0 0 2 2 1 0 NACHT domain AAA_11 PF13086.1 KKK13670.1 - 0.051 13.1 0.1 0.15 11.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain PhoH PF02562.11 KKK13670.1 - 0.058 12.6 0.0 0.13 11.4 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein ChlI PF13541.1 KKK13670.1 - 0.071 12.6 0.1 0.66 9.5 0.0 2.4 2 1 0 2 2 2 0 Subunit ChlI of Mg-chelatase AAA_24 PF13479.1 KKK13670.1 - 0.072 12.6 0.1 0.16 11.5 0.1 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 KKK13670.1 - 0.077 13.1 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 RNA helicase NTPase_1 PF03266.10 KKK13670.1 - 0.12 12.0 0.1 0.57 9.8 0.0 2.2 2 0 0 2 2 2 0 NTPase AAA_PrkA PF08298.6 KKK13670.1 - 0.17 10.5 0.0 1.4 7.5 0.0 2.1 2 0 0 2 2 2 0 PrkA AAA domain AAA_23 PF13476.1 KKK13670.1 - 0.19 12.0 0.0 0.19 12.0 0.0 2.6 1 1 0 3 3 2 0 AAA domain Cytochrom_C552 PF02335.10 KKK13671.1 - 5.4 5.5 9.1 0.92 8.1 3.4 1.8 2 1 0 2 2 2 0 Cytochrome c552 SLD3 PF08639.5 KKK13674.1 - 2.2e-146 488.3 2.0 3.1e-146 487.9 1.4 1.2 1 0 0 1 1 1 1 DNA replication regulator SLD3 ATP_bind_1 PF03029.12 KKK13675.1 - 4.8e-76 255.4 0.1 6.4e-76 255.0 0.1 1.2 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_17 PF13207.1 KKK13675.1 - 0.00016 22.5 0.0 0.00044 21.0 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KKK13675.1 - 0.00035 20.4 0.0 0.00071 19.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain UPF0079 PF02367.12 KKK13675.1 - 0.00059 19.4 0.1 0.0029 17.2 0.0 2.0 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_19 PF13245.1 KKK13675.1 - 0.0007 19.3 0.0 0.0015 18.2 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 KKK13675.1 - 0.0011 19.1 0.0 0.0028 17.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 KKK13675.1 - 0.0021 17.7 0.0 0.005 16.5 0.0 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 KKK13675.1 - 0.0024 17.7 0.0 0.0044 16.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 KKK13675.1 - 0.003 17.6 0.0 0.0077 16.3 0.0 1.7 1 0 0 1 1 1 1 RNA helicase AAA_16 PF13191.1 KKK13675.1 - 0.0042 17.0 0.3 0.059 13.3 0.0 2.3 2 1 0 2 2 2 1 AAA ATPase domain cobW PF02492.14 KKK13675.1 - 0.0054 16.2 0.1 0.22 10.9 0.0 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain T2SE PF00437.15 KKK13675.1 - 0.0069 15.3 0.0 0.013 14.3 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA PF00004.24 KKK13675.1 - 0.0071 16.5 0.0 0.02 15.1 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 KKK13675.1 - 0.0072 15.7 0.0 0.013 14.9 0.0 1.9 1 1 0 1 1 1 1 AAA-like domain NACHT PF05729.7 KKK13675.1 - 0.008 15.8 0.0 0.018 14.6 0.0 1.6 1 0 0 1 1 1 1 NACHT domain ABC_tran PF00005.22 KKK13675.1 - 0.014 15.6 0.0 0.14 12.4 0.0 2.1 2 0 0 2 2 2 0 ABC transporter AAA_31 PF13614.1 KKK13675.1 - 0.026 14.4 0.1 0.28 11.1 0.0 2.6 2 1 0 2 2 2 0 AAA domain AAA_24 PF13479.1 KKK13675.1 - 0.032 13.8 0.0 0.058 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 KKK13675.1 - 0.035 13.5 0.0 0.86 9.0 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation KAP_NTPase PF07693.9 KKK13675.1 - 0.039 12.9 0.0 0.067 12.1 0.0 1.7 1 1 0 1 1 1 0 KAP family P-loop domain Septin PF00735.13 KKK13675.1 - 0.045 12.7 0.1 0.11 11.5 0.0 1.6 2 0 0 2 2 2 0 Septin Arch_ATPase PF01637.13 KKK13675.1 - 0.048 13.3 0.0 0.15 11.7 0.0 1.9 2 1 0 2 2 2 0 Archaeal ATPase SRP54 PF00448.17 KKK13675.1 - 0.049 13.0 0.0 0.11 11.9 0.0 1.6 2 0 0 2 2 1 0 SRP54-type protein, GTPase domain FtsK_SpoIIIE PF01580.13 KKK13675.1 - 0.055 12.9 0.1 0.28 10.6 0.0 1.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_30 PF13604.1 KKK13675.1 - 0.055 13.0 0.0 0.13 11.8 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 KKK13675.1 - 0.073 12.6 0.0 0.22 11.0 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain NTPase_1 PF03266.10 KKK13675.1 - 0.085 12.5 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 NTPase GTP_EFTU PF00009.22 KKK13675.1 - 0.087 12.2 0.1 11 5.4 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain KaiC PF06745.8 KKK13675.1 - 0.095 11.8 0.0 0.2 10.7 0.0 1.5 1 0 0 1 1 1 0 KaiC Gtr1_RagA PF04670.7 KKK13675.1 - 0.1 11.7 0.0 0.41 9.7 0.0 2.0 3 0 0 3 3 3 0 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KKK13675.1 - 0.12 12.3 0.0 0.28 11.1 0.0 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase S-AdoMet_synt_C PF02773.11 KKK13676.1 - 1.1e-76 255.1 0.3 2.3e-76 254.1 0.2 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_N PF00438.15 KKK13676.1 - 1e-42 144.3 0.1 2.1e-42 143.3 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain S-AdoMet_synt_M PF02772.11 KKK13676.1 - 2.4e-27 95.2 0.1 2.8e-16 59.5 0.0 2.4 1 1 1 2 2 2 2 S-adenosylmethionine synthetase, central domain RNase_H PF00075.19 KKK13677.1 - 5.2e-20 72.1 0.0 6.8e-20 71.7 0.0 1.1 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.1 KKK13677.1 - 0.0018 18.0 0.1 0.037 13.8 0.0 2.3 2 1 0 2 2 2 1 Reverse transcriptase-like Apq12 PF12716.2 KKK13678.1 - 2.9e-18 65.2 12.7 4.9e-18 64.5 8.8 1.4 1 0 0 1 1 1 1 Nuclear pore assembly and biogenesis vMSA PF00695.14 KKK13678.1 - 0.019 14.1 0.2 0.027 13.6 0.2 1.3 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus DUF412 PF04217.8 KKK13678.1 - 0.068 12.9 3.0 0.12 12.1 2.1 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF412 SPC22 PF04573.7 KKK13693.1 - 6.6e-37 126.4 0.0 1.1e-25 89.8 0.0 2.1 2 0 0 2 2 2 2 Signal peptidase subunit ASD2 PF08687.6 KKK13693.1 - 0.058 12.7 0.6 0.075 12.3 0.4 1.1 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 NST1 PF13945.1 KKK13693.1 - 0.35 10.9 6.3 0.56 10.2 4.4 1.3 1 0 0 1 1 1 0 Salt tolerance down-regulator SR-25 PF10500.4 KKK13693.1 - 0.89 8.9 14.7 1.8 7.9 10.2 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein AIG2 PF06094.7 KKK13694.1 - 5.1e-05 23.6 0.4 0.00016 22.0 0.3 1.8 1 1 0 1 1 1 1 AIG2-like family Peptidase_C48 PF02902.14 KKK13695.1 - 2.6e-31 108.9 0.0 1.6e-30 106.3 0.0 2.1 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain IF4E PF01652.13 KKK13696.1 - 3.6e-52 176.2 0.1 5.2e-52 175.7 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Zip PF02535.17 KKK13696.1 - 0.0066 15.4 0.5 0.0066 15.4 0.4 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter SelP_N PF04592.9 KKK13696.1 - 1.2 8.4 9.6 1.7 8.0 6.6 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Pkinase PF00069.20 KKK13697.1 - 1.6e-69 233.9 0.0 2.4e-69 233.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK13697.1 - 1.3e-34 119.4 0.0 2.1e-34 118.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KKK13697.1 - 0.00013 21.0 0.1 0.0017 17.4 0.0 2.1 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.9 KKK13697.1 - 0.0043 16.1 0.1 0.0086 15.1 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PLU-1 PF08429.6 KKK13698.1 - 1.5e-104 349.5 13.3 4.5e-103 344.6 9.3 2.1 2 0 0 2 2 2 1 PLU-1-like protein JmjC PF02373.17 KKK13698.1 - 7.8e-44 148.5 0.2 1.7e-43 147.4 0.1 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase ARID PF01388.16 KKK13698.1 - 5.3e-27 93.5 0.1 2.2e-26 91.5 0.1 2.1 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain zf-C5HC2 PF02928.11 KKK13698.1 - 6.1e-18 64.6 3.3 1.5e-17 63.3 2.3 1.7 1 0 0 1 1 1 1 C5HC2 zinc finger PHD PF00628.24 KKK13698.1 - 2.2e-17 62.4 32.0 7.8e-10 38.2 5.2 3.5 3 0 0 3 3 3 2 PHD-finger zf-PHD-like PF15446.1 KKK13698.1 - 0.011 15.0 8.8 0.086 12.1 0.7 2.7 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain DNApol3-delta_C PF09115.5 KKK13698.1 - 0.24 11.4 0.0 0.64 10.0 0.0 1.7 1 0 0 1 1 1 0 DNA polymerase III, delta subunit, C terminal Spore_III_AB PF09548.5 KKK13698.1 - 0.64 9.7 2.5 1.3 8.7 0.3 2.3 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) zf-RING_2 PF13639.1 KKK13698.1 - 0.94 9.3 23.8 3.4 7.5 5.2 2.7 2 0 0 2 2 2 0 Ring finger domain C1_1 PF00130.17 KKK13698.1 - 3.2 7.5 18.6 0.42 10.3 0.5 3.3 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) WD40 PF00400.27 KKK13699.1 - 4.5e-44 146.8 2.8 7.2e-09 35.1 0.1 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 KKK13699.1 - 9.8e-30 102.2 0.9 2e-29 101.3 0.6 1.5 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex Nup160 PF11715.3 KKK13699.1 - 0.0072 14.5 4.0 0.37 8.8 0.1 3.8 2 1 2 4 4 4 2 Nucleoporin Nup120/160 GTP_cyclohydroI PF01227.17 KKK13700.1 - 1.3e-73 246.1 0.2 1.6e-73 245.7 0.1 1.1 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.1 KKK13700.1 - 0.004 17.0 0.0 0.0075 16.1 0.0 1.4 1 0 0 1 1 1 1 QueF-like protein NUDIX-like PF09296.6 KKK13701.1 - 8.3e-21 74.1 0.1 1.7e-20 73.1 0.0 1.6 1 0 0 1 1 1 1 NADH pyrophosphatase-like rudimentary NUDIX domain NUDIX PF00293.23 KKK13701.1 - 4.5e-15 55.4 0.1 8.5e-15 54.5 0.1 1.4 1 0 0 1 1 1 1 NUDIX domain DUF3991 PF13154.1 KKK13701.1 - 0.039 14.1 0.0 0.27 11.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3991) V-SNARE_C PF12352.3 KKK13701.1 - 0.041 13.9 0.0 0.084 12.9 0.0 1.5 1 0 0 1 1 1 0 Snare region anchored in the vesicle membrane C-terminus CN_hydrolase PF00795.17 KKK13702.1 - 4e-30 104.5 0.0 6.7e-30 103.8 0.0 1.4 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.12 KKK13702.1 - 5.4e-21 74.6 0.0 3.2e-20 72.0 0.0 2.0 1 1 0 1 1 1 1 NAD synthase Asn_synthase PF00733.16 KKK13702.1 - 0.025 14.0 0.0 0.046 13.2 0.0 1.4 1 0 0 1 1 1 0 Asparagine synthase HDA2-3 PF11496.3 KKK13703.1 - 4.4e-54 183.3 0.0 8.3e-54 182.4 0.0 1.5 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 FMO-like PF00743.14 KKK13703.1 - 1.4e-37 129.1 0.0 2.1e-22 79.0 0.0 3.1 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 KKK13703.1 - 1.5e-18 67.6 0.0 1.5e-17 64.3 0.0 2.8 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KKK13703.1 - 2.6e-11 43.5 3.2 4.6e-09 36.2 0.1 4.5 3 2 1 4 4 4 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 KKK13703.1 - 6.6e-11 42.4 0.0 1.6e-09 37.9 0.0 2.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KKK13703.1 - 2.5e-09 36.5 2.3 5.6e-07 28.7 0.0 3.0 4 0 0 4 4 4 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 KKK13703.1 - 6e-06 26.1 0.0 1.7e-05 24.7 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KKK13703.1 - 0.00017 20.7 0.0 0.0013 17.8 0.0 2.1 2 0 0 2 2 2 1 Thi4 family GAS PF13851.1 KKK13703.1 - 0.0027 16.9 6.7 0.0027 16.9 4.6 2.7 1 1 1 2 2 2 1 Growth-arrest specific micro-tubule binding DAO PF01266.19 KKK13703.1 - 0.037 12.9 0.0 1.8 7.4 0.0 3.1 3 0 0 3 3 3 0 FAD dependent oxidoreductase Semialdhyde_dh PF01118.19 KKK13703.1 - 0.055 13.7 0.0 0.51 10.6 0.0 2.7 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain DUF2422 PF10337.4 KKK13703.1 - 2.5 6.7 6.3 4.4 5.9 4.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) Sec20 PF03908.8 KKK13703.1 - 3.3 7.4 7.2 12 5.7 2.0 3.0 1 1 1 2 2 2 0 Sec20 T2SF PF00482.18 KKK13703.1 - 7.3 6.5 8.6 1.2 9.0 1.5 2.9 3 0 0 3 3 3 0 Type II secretion system (T2SS), protein F V_ATPase_I PF01496.14 KKK13703.1 - 7.9 4.1 18.5 15 3.2 12.8 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family POT1 PF02765.12 KKK13704.1 - 6.8e-11 42.2 0.0 1.1e-10 41.6 0.0 1.3 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 Cu-oxidase_3 PF07732.10 KKK13705.1 - 1.1e-40 137.9 1.7 5e-40 135.9 1.0 2.3 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 KKK13705.1 - 4.4e-27 94.2 9.8 3.1e-22 78.5 0.3 3.7 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 KKK13705.1 - 1e-21 77.5 0.0 3.2e-19 69.3 0.0 2.8 2 1 0 2 2 2 2 Multicopper oxidase ketoacyl-synt PF00109.21 KKK13706.1 - 1.6e-78 263.6 0.0 6.2e-77 258.4 0.0 2.5 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 KKK13706.1 - 8.8e-55 186.2 2.0 1.7e-53 182.0 0.0 3.0 3 0 0 3 3 3 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 KKK13706.1 - 9.5e-34 115.8 1.6 2.5e-33 114.4 0.3 2.5 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Thioesterase PF00975.15 KKK13706.1 - 1.9e-27 96.9 0.0 3.8e-27 95.9 0.0 1.5 1 0 0 1 1 1 1 Thioesterase domain PP-binding PF00550.20 KKK13706.1 - 1.1e-25 89.6 5.0 3.6e-13 49.5 0.5 2.6 2 0 0 2 2 2 2 Phosphopantetheine attachment site Thiolase_N PF00108.18 KKK13706.1 - 1.7e-05 23.9 0.1 4.8e-05 22.4 0.0 1.7 1 1 0 1 1 1 1 Thiolase, N-terminal domain Spore_III_AF PF09581.5 KKK13706.1 - 0.43 10.4 0.0 0.77 9.5 0.0 1.3 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) Transglut_core PF01841.14 KKK13708.1 - 7e-11 42.3 0.0 1.5e-10 41.2 0.0 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily SH3_2 PF07653.12 KKK13708.1 - 4.9e-09 35.5 0.1 1.3e-08 34.2 0.1 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KKK13708.1 - 6.9e-07 28.5 1.0 2.9e-06 26.5 0.0 2.3 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 KKK13708.1 - 1.9e-06 27.3 0.3 1.1e-05 24.8 0.1 2.2 2 0 0 2 2 2 1 Variant SH3 domain Helicase_C_3 PF13625.1 KKK13709.1 - 1.8e-27 95.6 0.0 5.7e-27 94.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KKK13709.1 - 4.4e-14 52.7 0.0 9.2e-14 51.6 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 KKK13709.1 - 2.1e-12 46.7 0.0 4.9e-12 45.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 KKK13709.1 - 3.2e-12 45.8 0.1 5.3e-12 45.1 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.24 KKK13709.1 - 1.3e-06 28.0 0.0 2.9e-06 26.8 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_34 PF13872.1 KKK13709.1 - 0.0024 16.6 0.0 0.0039 16.0 0.0 1.3 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 BCDHK_Adom3 PF10436.4 KKK13711.1 - 4.8e-47 159.5 0.1 9.5e-47 158.5 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 KKK13711.1 - 2.3e-10 40.1 0.0 1.1e-09 38.0 0.0 2.0 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.1 KKK13711.1 - 0.0025 17.5 0.0 0.8 9.4 0.0 2.4 2 0 0 2 2 2 2 Histidine kinase-like ATPase domain HATPase_c_3 PF13589.1 KKK13711.1 - 0.012 15.2 0.0 0.02 14.5 0.0 1.3 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase USP7_ICP0_bdg PF12436.3 KKK13712.1 - 7.5e-90 300.5 0.0 5.9e-89 297.5 0.0 2.1 2 0 0 2 2 2 1 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.1 KKK13712.1 - 5.2e-69 231.9 0.4 1.6e-67 227.0 0.0 2.8 2 0 0 2 2 2 1 Ubiquitin-specific protease C-terminal UCH PF00443.24 KKK13712.1 - 7.7e-55 185.8 0.4 1.6e-54 184.8 0.1 1.7 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KKK13712.1 - 1.9e-32 112.8 0.0 3.6e-32 111.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.21 KKK13712.1 - 1.7e-09 37.9 0.2 9.6e-09 35.5 0.0 2.4 2 0 0 2 2 2 1 MATH domain Rad60-SLD PF11976.3 KKK13712.1 - 0.0083 15.8 0.8 8.2 6.1 0.1 4.3 3 1 0 3 3 3 1 Ubiquitin-2 like Rad60 SUMO-like YukD PF08817.5 KKK13712.1 - 0.031 14.8 0.0 4.6 7.8 0.0 2.9 2 0 0 2 2 2 0 WXG100 protein secretion system (Wss), protein YukD E3_binding PF02817.12 KKK13712.1 - 0.33 10.6 0.8 0.56 9.8 0.0 1.8 2 0 0 2 2 2 0 e3 binding domain EMP24_GP25L PF01105.19 KKK13713.1 - 1.1e-46 158.8 2.4 1.3e-46 158.6 1.7 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Hydrophobin PF01185.13 KKK13715.1 - 0.013 15.9 7.3 0.026 14.9 5.0 1.6 1 0 0 1 1 1 0 Fungal hydrophobin CTD_bind PF04818.8 KKK13716.1 - 0.00055 20.1 0.0 0.0019 18.4 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase II-binding domain. XRN_N PF03159.13 KKK13719.1 - 1.2e-102 342.2 0.1 1.2e-102 342.2 0.0 1.9 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus R3H PF01424.17 KKK13719.1 - 0.002 17.7 0.0 0.13 11.9 0.0 2.6 2 0 0 2 2 2 1 R3H domain p450 PF00067.17 KKK13720.1 - 8.9e-34 116.7 0.0 1.1e-33 116.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Erg28 PF03694.8 KKK13739.1 - 2.3e-39 133.8 0.1 2.7e-39 133.6 0.1 1.0 1 0 0 1 1 1 1 Erg28 like protein adh_short PF00106.20 KKK13740.1 - 6.8e-21 74.9 0.0 1.2e-20 74.1 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KKK13740.1 - 3.1e-13 50.0 0.0 4.3e-13 49.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KKK13740.1 - 0.00013 21.6 0.0 0.00025 20.7 0.0 1.4 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KKK13740.1 - 0.0057 16.6 0.2 0.01 15.8 0.1 1.4 1 1 0 1 1 1 1 NADH(P)-binding 3HCDH_N PF02737.13 KKK13740.1 - 0.027 14.1 0.0 0.042 13.5 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 KKK13740.1 - 0.14 12.0 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Acetyltransf_1 PF00583.19 KKK13741.1 - 7.1e-11 41.9 0.0 1.3e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KKK13741.1 - 4.7e-09 36.2 0.0 7.8e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KKK13741.1 - 0.00098 18.9 0.0 0.0041 16.9 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 KKK13741.1 - 0.0058 16.5 0.0 0.022 14.7 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 KKK13741.1 - 0.032 14.1 0.1 0.064 13.1 0.1 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_8 PF13523.1 KKK13741.1 - 0.039 13.8 0.0 0.083 12.7 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KKK13741.1 - 0.065 13.3 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF619 PF04768.8 KKK13742.1 - 1.7e-53 180.5 0.0 2.2e-52 176.8 0.0 2.3 3 0 0 3 3 3 1 Protein of unknown function (DUF619) Sugar_tr PF00083.19 KKK13743.1 - 5.8e-137 456.9 31.1 6.6e-137 456.7 21.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KKK13743.1 - 1.3e-21 76.7 60.6 2.4e-19 69.2 23.1 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2530 PF10745.4 KKK13743.1 - 0.0059 16.5 1.3 0.028 14.3 0.9 2.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2530) NOGCT PF08155.6 KKK13744.1 - 7.6e-29 99.1 4.5 1.5e-28 98.2 3.1 1.5 1 0 0 1 1 1 1 NOGCT (NUC087) domain NOG1 PF06858.9 KKK13744.1 - 2.1e-27 94.7 0.4 4.9e-27 93.5 0.3 1.7 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.18 KKK13744.1 - 4.6e-15 55.5 0.0 1.1e-14 54.4 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KKK13744.1 - 1.4e-07 30.8 0.0 3.4e-07 29.6 0.0 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 KKK13744.1 - 1.5e-05 25.4 0.0 0.00031 21.2 0.0 2.5 2 0 0 2 2 2 1 Miro-like protein CbiA PF01656.18 KKK13744.1 - 0.027 13.8 0.3 0.08 12.3 0.0 1.9 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain Dynamin_N PF00350.18 KKK13744.1 - 0.03 14.1 0.0 7.1 6.4 0.0 2.7 1 1 1 2 2 2 0 Dynamin family SbcD_C PF12320.3 KKK13744.1 - 0.042 13.8 0.1 0.042 13.8 0.1 2.4 2 1 0 2 2 2 0 Type 5 capsule protein repressor C-terminal domain BAR_2 PF10455.4 KKK13745.1 - 6.7e-62 209.0 0.9 9.9e-62 208.4 0.6 1.2 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.13 KKK13745.1 - 1.8e-18 66.9 5.6 2.7e-17 63.0 3.9 2.0 1 1 0 1 1 1 1 BAR domain ATP-synt_B PF00430.13 KKK13745.1 - 0.0035 17.1 2.1 0.013 15.2 1.4 1.9 1 0 0 1 1 1 1 ATP synthase B/B' CF(0) Arv1 PF04161.8 KKK13747.1 - 1.9e-40 138.9 0.0 1.4e-35 123.1 0.0 2.1 2 0 0 2 2 2 2 Arv1-like family ATP_synt_H PF05493.8 KKK13748.1 - 2.4e-05 24.2 0.1 2.6e-05 24.2 0.1 1.0 1 0 0 1 1 1 1 ATP synthase subunit H Ureide_permease PF07168.6 KKK13748.1 - 0.017 13.8 0.1 0.017 13.8 0.0 1.0 1 0 0 1 1 1 0 Ureide permease PsbX PF06596.6 KKK13748.1 - 0.038 13.6 2.4 0.044 13.4 1.6 1.1 1 0 0 1 1 1 0 Photosystem II reaction centre X protein (PsbX) FixQ PF05545.6 KKK13748.1 - 0.04 13.5 0.1 0.049 13.2 0.1 1.2 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ P12 PF12669.2 KKK13748.1 - 0.093 12.9 0.4 0.1 12.8 0.3 1.1 1 0 0 1 1 1 0 Virus attachment protein p12 family AMP-binding PF00501.23 KKK13749.1 - 2.3e-61 207.4 0.0 3.1e-61 207.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KKK13749.1 - 1e-05 26.3 0.0 2e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ATG22 PF11700.3 KKK13750.1 - 8e-136 453.2 29.1 9.1e-136 453.1 20.2 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.11 KKK13750.1 - 1.8e-12 46.6 25.0 7.8e-07 28.1 4.6 3.2 2 1 1 3 3 3 3 Major Facilitator Superfamily DUF2721 PF11026.3 KKK13750.1 - 0.25 10.9 0.0 0.25 10.9 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2721) Thiolase_N PF00108.18 KKK13751.1 - 7.3e-68 228.4 1.3 1.4e-67 227.4 0.9 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 KKK13751.1 - 1.6e-39 134.1 0.1 3.3e-39 133.1 0.0 1.5 1 0 0 1 1 1 1 Thiolase, C-terminal domain HNH_2 PF13391.1 KKK13751.1 - 5.9e-10 38.7 0.2 1.3e-09 37.7 0.1 1.6 1 0 0 1 1 1 1 HNH endonuclease ACP_syn_III PF08545.5 KKK13751.1 - 0.0011 18.6 0.6 0.04 13.5 0.1 2.4 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.21 KKK13751.1 - 0.019 14.4 1.6 0.062 12.7 0.9 2.0 3 0 0 3 3 3 0 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III_C PF08541.5 KKK13751.1 - 0.12 12.4 0.0 0.33 10.9 0.0 1.8 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Spc97_Spc98 PF04130.8 KKK13752.1 - 5.4e-135 450.7 1.4 7e-135 450.4 1.0 1.1 1 0 0 1 1 1 1 Spc97 / Spc98 family Proteasome PF00227.21 KKK13753.1 - 1.4e-56 190.7 0.0 1.8e-56 190.4 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 KKK13753.1 - 9.2e-14 50.4 0.2 2.3e-13 49.2 0.0 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature KH_1 PF00013.24 KKK13754.1 - 0.0021 17.6 0.0 0.0078 15.8 0.0 2.0 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 KKK13754.1 - 0.0085 15.7 0.0 0.025 14.2 0.0 1.8 1 0 0 1 1 1 1 KH domain Methyltransf_11 PF08241.7 KKK13755.1 - 1.1e-10 41.7 0.0 2e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KKK13755.1 - 3.2e-10 39.9 0.0 5.1e-10 39.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KKK13755.1 - 7.1e-07 29.6 0.0 2.1e-06 28.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KKK13755.1 - 1.1e-06 28.3 0.1 0.009 15.6 0.0 2.4 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_4 PF02390.12 KKK13755.1 - 1.8e-05 23.8 0.0 6e-05 22.1 0.0 1.9 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_18 PF12847.2 KKK13755.1 - 7.5e-05 23.2 0.0 0.0014 19.1 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 KKK13755.1 - 0.0064 16.4 0.0 0.021 14.8 0.0 1.8 2 0 0 2 2 2 1 FtsJ-like methyltransferase Ubie_methyltran PF01209.13 KKK13755.1 - 0.0066 15.5 0.0 0.078 12.0 0.0 2.1 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_8 PF05148.10 KKK13755.1 - 0.087 12.4 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Hypothetical methyltransferase Methyltransf_25 PF13649.1 KKK13755.1 - 0.1 12.9 0.0 0.57 10.5 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_8 PF05148.10 KKK13756.1 - 1.5e-53 181.7 0.0 2e-51 174.6 0.0 2.6 3 0 0 3 3 3 1 Hypothetical methyltransferase Methyltransf_11 PF08241.7 KKK13756.1 - 6.9e-08 32.8 0.2 4.1e-07 30.4 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 KKK13756.1 - 0.015 15.6 0.0 0.61 10.4 0.0 2.5 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.1 KKK13756.1 - 0.023 14.3 2.3 0.054 13.1 0.0 2.5 3 0 0 3 3 3 0 Methyltransferase domain Methyltransf_23 PF13489.1 KKK13756.1 - 0.083 12.6 0.0 0.34 10.6 0.0 2.0 3 0 0 3 3 3 0 Methyltransferase domain Fungal_trans_2 PF11951.3 KKK13757.1 - 3.4e-17 62.1 0.8 1.6e-13 49.9 0.1 3.1 3 0 0 3 3 3 2 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK13757.1 - 3.7e-07 29.9 11.5 3.7e-07 29.9 8.0 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KKK13757.1 - 0.0043 15.9 0.1 0.0082 15.0 0.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain GalP_UDP_transf PF01087.17 KKK13758.1 - 6.9e-68 228.3 0.1 4e-66 222.5 0.0 2.3 2 0 0 2 2 2 2 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.12 KKK13758.1 - 7.8e-55 184.9 0.5 1.6e-54 183.9 0.2 1.6 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, C-terminal domain UDPGT PF00201.13 KKK13759.1 - 4.3e-08 32.1 0.0 7.8e-08 31.3 0.0 1.4 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase F-box-like PF12937.2 KKK13759.1 - 1.8e-05 24.3 0.4 4e-05 23.2 0.3 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KKK13759.1 - 0.0043 16.6 0.5 0.0093 15.6 0.3 1.5 1 0 0 1 1 1 1 F-box domain Glyco_tran_28_C PF04101.11 KKK13759.1 - 0.077 12.6 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain PRK PF00485.13 KKK13759.1 - 0.17 11.3 0.0 0.3 10.5 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family NAD_binding_2 PF03446.10 KKK13760.1 - 1.4e-10 41.2 2.8 5.2e-05 23.1 0.1 3.2 1 1 1 2 2 2 2 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 KKK13760.1 - 7.9e-09 35.6 0.0 1.5e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.12 KKK13760.1 - 0.055 13.8 0.2 0.16 12.3 0.2 2.0 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent SAP PF02037.22 KKK13764.1 - 4.7e-12 45.1 0.8 8.8e-11 41.0 0.0 2.3 2 0 0 2 2 2 1 SAP domain CDC27 PF09507.5 KKK13764.1 - 1.1 8.4 16.3 1.2 8.2 11.3 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Methyltransf_11 PF08241.7 KKK13765.1 - 0.0088 16.5 0.0 0.021 15.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain GST_N_3 PF13417.1 KKK13780.1 - 1.4e-10 41.2 0.0 2.6e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KKK13780.1 - 3e-09 36.7 0.0 5.2e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 KKK13780.1 - 2e-07 30.8 0.0 6e-07 29.3 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 KKK13780.1 - 2.3e-07 30.8 0.0 5.1e-07 29.7 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KKK13780.1 - 3.3e-07 30.0 0.2 6.6e-07 29.1 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KKK13780.1 - 9.9e-06 25.9 0.1 1.5e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain MetRS-N PF09635.5 KKK13780.1 - 0.035 14.4 0.0 0.079 13.3 0.0 1.6 1 0 0 1 1 1 0 MetRS-N binding domain APH PF01636.18 KKK13781.1 - 8.2e-14 51.9 0.0 5.2e-13 49.2 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family DUF3680 PF12441.3 KKK13781.1 - 0.098 12.5 0.6 2.2 8.1 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3680) Acetyltransf_3 PF13302.1 KKK13782.1 - 8.1e-14 51.9 0.0 1e-13 51.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KKK13782.1 - 1e-11 44.6 0.1 1.7e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 KKK13782.1 - 7.3e-09 35.7 0.0 1.2e-08 35.0 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KKK13782.1 - 0.00012 22.1 0.0 0.00021 21.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KKK13782.1 - 0.00021 21.2 0.1 0.0005 19.9 0.0 1.9 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain AA_permease_2 PF13520.1 KKK13785.1 - 3.4e-37 127.9 47.3 4.2e-37 127.6 32.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KKK13785.1 - 1.7e-16 59.6 38.9 2.2e-16 59.3 27.0 1.1 1 0 0 1 1 1 1 Amino acid permease Abhydrolase_6 PF12697.2 KKK13786.1 - 1.6e-19 70.7 0.1 3.9e-18 66.1 0.0 2.3 2 1 0 2 2 2 1 Alpha/beta hydrolase family DSBA PF01323.15 KKK13786.1 - 4.7e-13 49.1 0.0 7.4e-13 48.4 0.0 1.3 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Abhydrolase_5 PF12695.2 KKK13786.1 - 1.3e-07 31.4 0.0 3.5e-07 30.0 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KKK13786.1 - 0.048 13.2 0.0 0.1 12.1 0.0 1.6 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_8 PF06259.7 KKK13786.1 - 0.11 11.9 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase Agglutinin PF07468.6 KKK13787.1 - 0.16 11.9 0.0 0.22 11.4 0.0 1.1 1 0 0 1 1 1 0 Agglutinin Peptidase_S15 PF02129.13 KKK13788.1 - 1.6e-38 132.7 0.3 1.2e-36 126.5 0.2 2.1 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.5 KKK13788.1 - 6.1e-13 49.1 0.0 1e-12 48.4 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Abhydrolase_6 PF12697.2 KKK13788.1 - 4e-05 23.6 0.1 7.9e-05 22.6 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KKK13788.1 - 0.0012 18.6 0.4 0.019 14.8 0.3 2.3 2 0 0 2 2 2 1 Putative lysophospholipase IN_DBD_C PF00552.16 KKK13788.1 - 0.011 15.1 0.2 0.033 13.6 0.1 1.8 1 0 0 1 1 1 0 Integrase DNA binding domain GST_N_3 PF13417.1 KKK13789.1 - 5.8e-18 64.8 0.1 1e-17 64.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KKK13789.1 - 9.3e-15 54.3 0.0 1.7e-14 53.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 KKK13789.1 - 1.1e-09 38.3 0.0 2.3e-09 37.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.19 KKK13789.1 - 0.00017 21.5 0.0 0.00027 20.8 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin p450 PF00067.17 KKK13791.1 - 3.5e-57 193.9 0.0 5.2e-57 193.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.13 KKK13792.1 - 1.9e-13 49.9 0.0 6.6e-13 48.1 0.0 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK13792.1 - 3.3e-07 30.0 15.5 7.5e-07 28.9 10.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldo_ket_red PF00248.16 KKK13793.1 - 2.4e-52 177.4 0.0 3e-52 177.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family GMC_oxred_N PF00732.14 KKK13794.1 - 3.3e-79 266.1 0.0 4.8e-79 265.5 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KKK13794.1 - 1.3e-36 126.0 0.0 3.1e-36 124.8 0.0 1.6 1 1 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 KKK13794.1 - 5.4e-07 28.8 0.2 0.012 14.4 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 KKK13794.1 - 4.4e-06 25.8 0.5 0.0058 15.5 0.3 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KKK13794.1 - 0.00061 18.8 0.1 0.00099 18.1 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein GIDA PF01134.17 KKK13794.1 - 0.0023 16.8 0.1 0.031 13.1 0.0 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.9 KKK13794.1 - 0.0084 16.0 0.0 0.018 14.9 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KKK13794.1 - 0.016 14.3 0.2 0.15 11.1 0.1 2.0 2 0 0 2 2 2 0 Thi4 family NAD_binding_8 PF13450.1 KKK13794.1 - 0.029 14.3 0.4 0.076 13.0 0.3 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 KKK13794.1 - 0.07 12.1 3.9 0.038 13.0 0.7 2.0 3 0 0 3 3 3 0 FAD dependent oxidoreductase HI0933_like PF03486.9 KKK13794.1 - 0.075 11.4 0.3 0.17 10.3 0.2 1.6 2 0 0 2 2 2 0 HI0933-like protein Trp_halogenase PF04820.9 KKK13794.1 - 0.12 10.9 0.1 0.19 10.2 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase DASH_Dam1 PF08653.5 KKK13801.1 - 1.4e-29 101.5 1.3 1.9e-29 101.1 0.9 1.2 1 0 0 1 1 1 1 DASH complex subunit Dam1 Ribosomal_60s PF00428.14 KKK13801.1 - 0.0041 17.4 0.1 0.0064 16.8 0.1 1.2 1 0 0 1 1 1 1 60s Acidic ribosomal protein UCH PF00443.24 KKK13802.1 - 7.3e-54 182.6 0.0 1e-53 182.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KKK13802.1 - 4.7e-23 82.0 0.0 7.2e-23 81.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 KKK13802.1 - 0.00018 21.5 0.3 0.00018 21.5 0.2 2.4 4 0 0 4 4 4 1 Zn-finger in ubiquitin-hydrolases and other protein Nitroreductase PF00881.19 KKK13803.1 - 8.2e-16 58.2 0.0 1e-15 57.9 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family Ribosomal_S14 PF00253.16 KKK13804.1 - 7.9e-06 25.1 0.4 8.2e-06 25.1 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e HIT PF01230.18 KKK13805.1 - 1.1e-22 80.4 0.2 1.4e-22 80.0 0.1 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 KKK13805.1 - 6.9e-14 52.0 0.0 1.1e-13 51.4 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 KKK13805.1 - 3.2e-05 23.5 0.0 4.4e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CRAL_TRIO PF00650.15 KKK13806.1 - 2.4e-43 147.3 0.1 4.5e-43 146.5 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 KKK13806.1 - 1.3e-15 57.1 0.2 4.7e-15 55.4 0.1 1.9 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 KKK13806.1 - 6.9e-09 35.7 0.0 1.2e-08 35.0 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Peptidase_M20 PF01546.23 KKK13807.1 - 0.07 12.6 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 Cullin PF00888.17 KKK13808.1 - 1.6e-118 396.8 0.0 1.9e-118 396.5 0.0 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 KKK13808.1 - 2.9e-25 87.8 1.5 7.5e-25 86.5 1.0 1.8 1 0 0 1 1 1 1 Cullin protein neddylation domain HbrB PF08539.6 KKK13808.1 - 0.00077 19.3 0.0 0.0017 18.1 0.0 1.6 1 0 0 1 1 1 1 HbrB-like TrmB PF01978.14 KKK13808.1 - 0.026 14.2 0.1 4.9 6.9 0.1 2.5 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB DUF605 PF04652.11 KKK13808.1 - 0.87 8.9 10.2 1.6 8.0 7.0 1.3 1 0 0 1 1 1 0 Vta1 like DUF3414 PF11894.3 KKK13809.1 - 0 1628.8 15.4 0 1628.5 10.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3414) UPF0052 PF01933.13 KKK13810.1 - 7.2e-53 179.8 0.0 9.2e-53 179.5 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 Head-tail_con PF12236.3 KKK13810.1 - 0.18 10.1 0.0 0.25 9.6 0.0 1.1 1 0 0 1 1 1 0 Bacteriophage head to tail connecting protein TAN PF11640.3 KKK13811.1 - 6.1e-52 175.4 2.5 2.7e-51 173.3 1.3 2.6 2 0 0 2 2 2 1 Telomere-length maintenance and DNA damage repair PI3_PI4_kinase PF00454.22 KKK13811.1 - 2.8e-45 154.6 0.0 5.4e-45 153.6 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 KKK13811.1 - 9.3e-13 47.3 0.7 5.8e-11 41.6 0.1 3.0 3 0 0 3 3 3 1 FATC domain DUF1353 PF07087.6 KKK13811.1 - 0.031 13.7 0.0 0.16 11.4 0.0 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1353) SQS_PSY PF00494.14 KKK13812.1 - 2e-44 151.8 1.3 3.4e-44 151.1 0.9 1.3 1 0 0 1 1 1 1 Squalene/phytoene synthase CorA PF01544.13 KKK13813.1 - 2.2e-27 95.8 9.9 8.5e-19 67.6 1.2 3.2 3 0 0 3 3 3 3 CorA-like Mg2+ transporter protein DUF1143 PF06608.6 KKK13813.1 - 0.082 12.9 0.2 0.15 12.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1143) zf-C3HC4_2 PF13923.1 KKK13814.1 - 0.14 12.1 0.7 0.24 11.4 0.5 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DNA_pol_A PF00476.15 KKK13815.1 - 2.9e-99 332.2 0.0 4.1e-99 331.7 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family A Mad3_BUB1_I PF08311.7 KKK13815.1 - 0.038 13.7 0.5 0.087 12.6 0.3 1.6 1 0 0 1 1 1 0 Mad3/BUB1 homology region 1 DNA_pol_A_exo1 PF01612.15 KKK13815.1 - 0.074 12.5 0.3 1.9 7.9 0.2 2.7 1 1 0 1 1 1 0 3'-5' exonuclease DltD_C PF04914.7 KKK13815.1 - 0.084 12.7 0.0 0.21 11.4 0.0 1.6 1 0 0 1 1 1 0 DltD C-terminal region SNF2_N PF00176.18 KKK13816.1 - 1.4e-68 230.8 0.0 1.9e-68 230.4 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.6 KKK13816.1 - 6e-21 74.3 0.0 1.2e-20 73.3 0.0 1.6 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.26 KKK13816.1 - 2.1e-14 53.1 0.0 7.5e-14 51.3 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.1 KKK13816.1 - 1.1e-07 31.8 8.7 1.9e-07 30.9 6.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KKK13816.1 - 5.8e-05 22.6 5.1 0.0001 21.8 3.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KKK13816.1 - 0.00027 20.6 7.5 0.00051 19.8 5.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 KKK13816.1 - 0.00037 20.0 8.1 0.00068 19.2 5.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KKK13816.1 - 0.0012 18.5 6.2 0.0022 17.6 4.3 1.5 1 0 0 1 1 1 1 zinc-RING finger domain UBA_4 PF14555.1 KKK13816.1 - 0.069 12.6 0.0 0.22 11.0 0.0 1.8 1 0 0 1 1 1 0 UBA-like domain zf-C3HC4_4 PF15227.1 KKK13816.1 - 0.11 12.3 7.8 0.21 11.4 5.4 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 KKK13816.1 - 0.13 12.0 5.5 0.32 10.7 3.8 1.7 1 0 0 1 1 1 0 RING-type zinc-finger Cut12 PF11500.3 KKK13817.1 - 4.8e-50 169.1 16.5 4.8e-50 169.1 11.5 4.1 3 1 2 5 5 5 1 Spindle pole body formation-associated protein Glutaredoxin2_C PF04399.8 KKK13817.1 - 2.2 7.8 14.8 0.17 11.4 1.4 3.3 3 0 0 3 3 3 0 Glutaredoxin 2, C terminal domain Pkinase PF00069.20 KKK13818.1 - 3.4e-30 105.0 0.0 1.8e-14 53.5 0.0 4.0 3 1 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 KKK13818.1 - 4.7e-21 75.0 0.0 4.9e-13 48.7 0.0 2.8 2 1 0 2 2 2 2 Protein tyrosine kinase RWD PF05773.17 KKK13818.1 - 1.4e-16 60.4 0.1 2.8e-16 59.3 0.1 1.6 1 0 0 1 1 1 1 RWD domain HSP70 PF00012.15 KKK13818.1 - 9.2 4.0 8.4 14 3.4 5.8 1.2 1 0 0 1 1 1 0 Hsp70 protein Aminotran_3 PF00202.16 KKK13819.1 - 1.4e-96 323.3 0.0 1.8e-96 322.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Spt4 PF06093.8 KKK13820.1 - 1.4e-32 111.3 0.1 1.7e-32 111.1 0.1 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger NmrA PF05368.8 KKK13821.1 - 2.7e-32 111.9 0.0 3.9e-32 111.3 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KKK13821.1 - 7.6e-07 29.3 0.5 1.2e-06 28.7 0.4 1.2 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 KKK13821.1 - 0.00068 18.4 0.0 0.0013 17.5 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.13 KKK13821.1 - 0.014 15.4 0.0 0.022 14.7 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain p450 PF00067.17 KKK13822.1 - 1.7e-24 86.1 0.0 3e-24 85.3 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 adh_short_C2 PF13561.1 KKK13823.1 - 2.8e-24 86.2 0.5 3.1e-24 86.0 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KKK13823.1 - 2.3e-11 43.9 0.1 3.1e-11 43.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KKK13823.1 - 8.3e-06 25.5 0.0 1.2e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KKK13823.1 - 1.6e-05 24.9 0.4 5.2e-05 23.3 0.2 1.8 1 1 1 2 2 2 1 NADH(P)-binding NAD_binding_7 PF13241.1 KKK13823.1 - 0.003 17.8 0.1 0.0087 16.2 0.0 1.8 2 0 0 2 2 2 1 Putative NAD(P)-binding THF_DHG_CYH_C PF02882.14 KKK13823.1 - 0.033 13.2 0.6 0.11 11.6 0.0 2.0 2 1 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.16 KKK13823.1 - 0.049 13.0 0.0 0.071 12.5 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 KKK13823.1 - 0.064 13.0 0.3 0.22 11.3 0.1 1.9 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Glyco_tran_WecB PF03808.8 KKK13823.1 - 0.099 12.0 0.0 0.32 10.3 0.0 1.8 2 0 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family FAD_binding_3 PF01494.14 KKK13824.1 - 6e-17 61.7 1.5 2.1e-15 56.6 1.0 2.5 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 KKK13824.1 - 1e-11 44.3 3.1 3.8e-06 26.0 0.0 2.3 1 1 1 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KKK13824.1 - 2.4e-06 26.6 0.4 4.5e-06 25.7 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 KKK13824.1 - 0.0015 18.4 1.0 0.0099 15.7 0.7 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KKK13824.1 - 0.0019 16.7 0.2 0.0078 14.7 0.2 1.8 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.1 KKK13824.1 - 0.0032 17.4 0.4 0.0088 16.0 0.3 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 KKK13824.1 - 0.0065 15.5 0.1 0.0081 15.2 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 KKK13824.1 - 0.0098 14.7 0.2 0.014 14.2 0.1 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A DUF4434 PF14488.1 KKK13824.1 - 0.049 13.3 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4434) BRCA-2_OB3 PF09104.5 KKK13824.1 - 0.15 11.8 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 BRCA2, oligonucleotide/oligosaccharide-binding, domain 3 Lycopene_cycl PF05834.7 KKK13824.1 - 0.29 10.0 1.0 5.3 5.8 0.1 2.6 3 0 0 3 3 3 0 Lycopene cyclase protein NmrA PF05368.8 KKK13825.1 - 4.2e-26 91.6 0.0 5.1e-24 84.8 0.0 2.1 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KKK13825.1 - 3.2e-12 46.8 0.1 4.7e-12 46.2 0.1 1.2 1 0 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 KKK13825.1 - 0.00016 20.7 0.0 0.00022 20.3 0.0 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase KR PF08659.5 KKK13825.1 - 0.0082 15.8 0.4 0.015 14.9 0.3 1.4 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 KKK13825.1 - 0.072 12.9 0.6 0.14 12.0 0.2 1.6 2 0 0 2 2 2 0 short chain dehydrogenase DapB_N PF01113.15 KKK13825.1 - 0.14 12.0 0.2 0.24 11.3 0.1 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.19 KKK13825.1 - 0.15 12.3 0.1 0.29 11.4 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain p450 PF00067.17 KKK13826.1 - 8.8e-42 143.1 0.0 1.2e-41 142.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 ERbeta_N PF12497.3 KKK13826.1 - 0.063 13.1 0.1 1.3 8.9 0.0 2.3 2 0 0 2 2 2 0 Estrogen receptor beta MBOAT_2 PF13813.1 KKK13827.1 - 6e-21 74.3 2.6 1.3e-20 73.1 1.8 1.6 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family NmrA PF05368.8 KKK13828.1 - 3.1e-34 118.2 0.0 4.3e-34 117.7 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KKK13828.1 - 2.8e-13 50.2 0.1 4e-13 49.7 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 KKK13828.1 - 5.6e-06 25.5 0.1 7e-06 25.2 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Semialdhyde_dh PF01118.19 KKK13828.1 - 0.00051 20.3 0.1 0.0019 18.5 0.0 1.9 2 1 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain F420_oxidored PF03807.12 KKK13828.1 - 0.00098 19.5 0.2 0.009 16.4 0.0 2.2 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent KR PF08659.5 KKK13828.1 - 0.011 15.3 0.5 0.023 14.3 0.3 1.6 1 1 0 1 1 1 0 KR domain adh_short PF00106.20 KKK13828.1 - 0.02 14.8 0.6 0.035 14.0 0.3 1.6 1 1 0 1 1 1 0 short chain dehydrogenase DapB_N PF01113.15 KKK13828.1 - 0.026 14.4 0.1 0.048 13.5 0.1 1.5 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus TrkA_N PF02254.13 KKK13828.1 - 0.041 13.8 0.0 0.092 12.7 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain 3Beta_HSD PF01073.14 KKK13828.1 - 0.097 11.3 0.1 0.2 10.3 0.0 1.5 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Trp_DMAT PF11991.3 KKK13829.1 - 8.5e-97 324.5 0.0 1.1e-96 324.2 0.0 1.1 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase DUF1769 PF08588.5 KKK13829.1 - 0.016 15.1 0.0 0.04 13.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1769) NmrA PF05368.8 KKK13830.1 - 2.3e-29 102.3 0.0 3.2e-29 101.8 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KKK13830.1 - 5.9e-14 52.4 0.0 8.3e-14 52.0 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 KKK13830.1 - 1.2e-05 24.1 0.0 2.6e-05 23.0 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family F420_oxidored PF03807.12 KKK13830.1 - 0.0044 17.4 0.2 0.024 15.0 0.0 2.3 3 0 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent Saccharop_dh PF03435.13 KKK13830.1 - 0.006 15.6 0.0 0.0092 14.9 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase TrkA_N PF02254.13 KKK13830.1 - 0.008 16.1 0.1 0.019 14.9 0.0 1.6 2 0 0 2 2 2 1 TrkA-N domain Epimerase PF01370.16 KKK13830.1 - 0.02 14.3 0.0 0.039 13.3 0.0 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family KR PF08659.5 KKK13830.1 - 0.079 12.6 0.1 0.2 11.3 0.0 1.6 1 0 0 1 1 1 0 KR domain Methyltransf_31 PF13847.1 KKK13831.1 - 8.9e-10 38.3 0.0 2.2e-09 37.1 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 KKK13831.1 - 9.5e-08 32.3 0.1 2.1e-07 31.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KKK13831.1 - 1.4e-06 28.6 0.1 7e-06 26.4 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KKK13831.1 - 8.2e-06 26.3 0.3 1.8e-05 25.2 0.1 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 KKK13831.1 - 1.3e-05 24.9 0.0 2.7e-05 23.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KKK13831.1 - 7.2e-05 23.2 0.1 0.00026 21.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 KKK13831.1 - 0.00043 20.2 0.2 0.00081 19.4 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain CheR PF01739.13 KKK13831.1 - 0.00052 19.3 0.0 0.00076 18.8 0.0 1.2 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain Methyltransf_4 PF02390.12 KKK13831.1 - 0.038 13.0 0.0 0.075 12.0 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Ubie_methyltran PF01209.13 KKK13831.1 - 0.048 12.7 0.0 0.076 12.1 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family p450 PF00067.17 KKK13832.1 - 1.8e-65 221.2 0.0 2.2e-65 220.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Trp_DMAT PF11991.3 KKK13833.1 - 3.3e-85 286.4 0.0 4.6e-85 285.9 0.0 1.2 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase PhyH PF05721.8 KKK13834.1 - 7.2e-23 81.7 0.0 1e-22 81.2 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.7 KKK13834.1 - 1.3e-06 27.2 0.0 4e-06 25.5 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1479) p450 PF00067.17 KKK13835.1 - 2.7e-42 144.8 0.0 6.7e-42 143.5 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 AMP-binding PF00501.23 KKK13836.1 - 1.3e-156 521.2 0.5 3.3e-79 266.2 0.0 2.6 3 0 0 3 3 3 2 AMP-binding enzyme NAD_binding_4 PF07993.7 KKK13836.1 - 5.3e-42 143.4 0.0 1e-41 142.5 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein Condensation PF00668.15 KKK13836.1 - 5.7e-37 127.1 0.0 8.9e-36 123.2 0.0 2.4 2 0 0 2 2 2 1 Condensation domain PP-binding PF00550.20 KKK13836.1 - 5.7e-16 58.5 0.4 1.1e-06 28.8 0.1 2.8 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding_C PF13193.1 KKK13836.1 - 6.5e-09 36.6 0.1 9.7e-05 23.2 0.1 3.0 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain Epimerase PF01370.16 KKK13836.1 - 1.7e-08 34.1 0.1 1.3e-07 31.3 0.0 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 KKK13836.1 - 0.011 14.7 0.0 4.7 6.0 0.0 2.5 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 KKK13836.1 - 0.021 14.8 0.3 0.54 10.2 0.1 2.6 2 0 0 2 2 2 0 NADH(P)-binding 3Beta_HSD PF01073.14 KKK13836.1 - 0.06 12.0 0.1 0.19 10.3 0.0 1.8 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family FAD_binding_4 PF01565.18 KKK13837.1 - 5.4e-18 64.8 4.4 1.8e-17 63.1 3.0 1.9 1 1 0 1 1 1 1 FAD binding domain BBE PF08031.7 KKK13837.1 - 1.1e-05 25.2 0.0 2.3e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like PhyH PF05721.8 KKK13838.1 - 5.6e-21 75.5 0.1 1e-20 74.6 0.1 1.4 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.7 KKK13838.1 - 0.00019 20.0 0.0 0.00067 18.2 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1479) DUF89 PF01937.14 KKK13839.1 - 5.8e-137 456.2 0.0 6.5e-137 456.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 Metallophos PF00149.23 KKK13840.1 - 6.5e-39 133.4 0.0 9.4e-39 132.8 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PPP5 PF08321.7 KKK13840.1 - 5.8e-31 106.3 0.3 1.3e-30 105.2 0.2 1.6 1 0 0 1 1 1 1 PPP5 TPR repeat region TPR_11 PF13414.1 KKK13840.1 - 2.4e-20 71.9 5.0 2.2e-16 59.2 0.6 2.6 1 1 2 3 3 3 3 TPR repeat TPR_1 PF00515.23 KKK13840.1 - 1.1e-10 40.5 4.6 0.00019 20.8 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 KKK13840.1 - 3.3e-09 35.9 6.6 0.0042 16.8 0.0 3.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 KKK13840.1 - 7.8e-08 32.7 2.7 0.0044 17.6 0.2 2.7 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 KKK13840.1 - 0.0011 19.2 0.6 0.36 11.1 0.0 2.9 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.1 KKK13840.1 - 0.0027 17.5 0.4 0.012 15.5 0.3 2.0 1 1 1 2 2 2 2 Tetratricopeptide repeat Apc3 PF12895.2 KKK13840.1 - 0.015 15.3 0.7 0.19 11.8 0.3 2.3 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 KKK13840.1 - 0.016 15.8 2.6 2.6 8.9 0.3 3.5 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 KKK13840.1 - 0.019 15.4 1.0 3 8.5 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat MIT PF04212.13 KKK13840.1 - 0.019 14.8 3.9 0.11 12.4 0.7 2.3 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain BTB PF00651.26 KKK13842.1 - 0.11 12.4 0.0 0.26 11.3 0.0 1.6 1 0 0 1 1 1 0 BTB/POZ domain Peptidase_M1 PF01433.15 KKK13843.1 - 2.5e-72 244.1 0.0 3.3e-72 243.7 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M1 Leuk-A4-hydro_C PF09127.6 KKK13843.1 - 6.5e-44 149.0 0.0 1.2e-43 148.1 0.0 1.5 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_MA_2 PF13485.1 KKK13843.1 - 9.6e-17 61.2 0.1 1.7e-16 60.4 0.1 1.4 1 0 0 1 1 1 1 Peptidase MA superfamily Peptidase_M61 PF05299.7 KKK13843.1 - 0.065 13.2 1.7 0.29 11.1 1.2 2.1 1 1 0 1 1 1 0 M61 glycyl aminopeptidase Big_4 PF07532.6 KKK13843.1 - 0.07 12.6 1.0 0.8 9.2 0.1 2.4 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 4) Ubiq_cyt_C_chap PF03981.7 KKK13844.1 - 6.5e-39 133.0 0.1 1.9e-38 131.4 0.0 1.7 2 0 0 2 2 2 1 Ubiquinol-cytochrome C chaperone NumbF PF06311.7 KKK13844.1 - 0.015 15.3 0.9 0.031 14.3 0.6 1.5 1 0 0 1 1 1 0 NUMB domain TIP41 PF04176.8 KKK13845.1 - 2.7e-61 205.9 2.9 6.8e-52 175.3 0.0 2.0 1 1 1 2 2 2 2 TIP41-like family MIT PF04212.13 KKK13846.1 - 2.9e-09 36.6 1.0 1.5e-08 34.4 0.4 2.4 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain Zn_clus PF00172.13 KKK13847.1 - 3.1e-08 33.3 6.8 3.1e-08 33.3 4.7 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KKK13847.1 - 0.00038 19.4 0.0 0.0013 17.6 0.0 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain CDC45 PF02724.9 KKK13847.1 - 0.22 9.4 2.9 0.35 8.8 2.0 1.2 1 0 0 1 1 1 0 CDC45-like protein PBP1_TM PF14812.1 KKK13847.1 - 0.86 9.9 11.4 2.2 8.6 7.9 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Sigma70_ner PF04546.8 KKK13847.1 - 3.2 7.3 10.2 5.4 6.5 7.0 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region CENP-B_dimeris PF09026.5 KKK13847.1 - 5 7.4 16.4 13 6.1 11.4 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Peptidase_M24 PF00557.19 KKK13849.1 - 8.1e-56 188.8 0.0 1.1e-55 188.4 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 KKK13849.1 - 1.3e-24 86.0 0.0 4.8e-24 84.2 0.0 1.9 2 0 0 2 2 2 1 Aminopeptidase P, N-terminal domain 4HBT PF03061.17 KKK13850.1 - 7.4e-13 48.4 0.1 1e-12 47.9 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.1 KKK13850.1 - 0.061 13.3 0.0 0.072 13.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4442) PC4 PF02229.11 KKK13851.1 - 1.7e-22 78.3 0.2 3.5e-22 77.3 0.0 1.6 2 0 0 2 2 2 1 Transcriptional Coactivator p15 (PC4) PXA PF02194.10 KKK13852.1 - 1.4e-37 129.0 0.1 3.8e-37 127.6 0.0 1.8 1 0 0 1 1 1 1 PXA domain Nexin_C PF08628.7 KKK13852.1 - 6.7e-24 84.1 0.1 3.2e-23 81.9 0.0 2.4 2 0 0 2 2 2 1 Sorting nexin C terminal PX PF00787.19 KKK13852.1 - 4.4e-09 36.1 0.1 6.6e-08 32.3 0.0 2.4 2 0 0 2 2 2 1 PX domain DUF3944 PF13099.1 KKK13852.1 - 0.24 10.9 1.1 0.43 10.1 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3944) DDHD PF02862.12 KKK13853.1 - 1.7e-63 214.4 1.7 1.7e-63 214.4 1.1 3.2 2 2 0 2 2 2 1 DDHD domain PGAP1 PF07819.8 KKK13853.1 - 0.1 12.1 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Usp PF00582.21 KKK13853.1 - 0.14 12.3 1.0 0.37 10.9 0.7 1.6 1 0 0 1 1 1 0 Universal stress protein family CH PF00307.26 KKK13854.1 - 1.4e-65 218.0 0.0 4e-20 71.8 0.0 4.1 4 0 0 4 4 4 4 Calponin homology (CH) domain EF-hand_7 PF13499.1 KKK13854.1 - 1.9e-08 34.2 1.2 1e-05 25.5 0.3 2.8 2 0 0 2 2 2 2 EF-hand domain pair CAMSAP_CH PF11971.3 KKK13854.1 - 4.5e-05 23.0 0.0 0.81 9.3 0.0 4.0 4 0 0 4 4 4 2 CAMSAP CH domain EF-hand_6 PF13405.1 KKK13854.1 - 0.00089 18.9 4.2 0.05 13.4 0.0 3.2 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.27 KKK13854.1 - 0.00096 18.2 1.8 0.86 9.0 0.0 3.4 3 0 0 3 3 3 2 EF hand EF-hand_5 PF13202.1 KKK13854.1 - 0.014 14.7 2.8 1.1 8.6 0.2 2.9 2 0 0 2 2 2 0 EF hand RRM_1 PF00076.17 KKK13855.1 - 1.2e-11 44.0 0.0 1.7e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KKK13855.1 - 7.5e-08 32.2 0.0 1.1e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KKK13855.1 - 3.8e-07 29.8 0.0 5.3e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KKK13855.1 - 0.0027 17.4 0.0 0.0041 16.8 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Mito_carr PF00153.22 KKK13856.1 - 6.4e-72 237.3 0.9 6.5e-23 80.2 0.0 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein Ribosomal_L18e PF00828.14 KKK13856.1 - 9.4e-25 87.4 0.1 1.8e-24 86.5 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 Aldedh PF00171.17 KKK13857.1 - 4.4e-15 54.9 7.2 7.9e-10 37.6 4.3 2.9 2 1 0 2 2 2 2 Aldehyde dehydrogenase family Erf4 PF10256.4 KKK13857.1 - 0.094 12.5 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Golgin subfamily A member 7/ERF4 family Tbf5 PF06331.7 KKK13857.1 - 0.23 11.2 1.2 1.1 9.0 0.0 2.5 2 1 1 3 3 3 0 Transcription factor TFIIH complex subunit Tfb5 PCI PF01399.22 KKK13858.1 - 0.002 18.3 0.0 0.014 15.6 0.0 2.4 3 0 0 3 3 3 1 PCI domain TPR_1 PF00515.23 KKK13858.1 - 0.032 13.8 0.2 0.069 12.7 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.12 KKK13858.1 - 0.036 13.9 0.1 0.094 12.6 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_8 PF13181.1 KKK13858.1 - 0.051 13.3 0.2 0.17 11.7 0.1 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat GPI-anchored PF10342.4 KKK13859.1 - 1.2e-13 51.3 0.0 2.4e-13 50.3 0.0 1.5 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family KRE9 PF05390.6 KKK13859.1 - 5.8e-10 39.4 3.6 5.8e-10 39.4 2.5 1.6 2 0 0 2 2 2 1 Yeast cell wall synthesis protein KRE9/KNH1 AA_kinase PF00696.23 KKK13860.1 - 1.9e-38 132.4 0.6 2.8e-38 131.8 0.4 1.3 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.15 KKK13860.1 - 1.2e-17 63.3 0.2 5e-16 58.1 0.0 2.4 2 0 0 2 2 2 1 PUA domain PALP PF00291.20 KKK13861.1 - 1e-60 205.5 0.1 1.2e-60 205.3 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.23 KKK13861.1 - 6.6e-09 35.4 0.1 2.7e-06 27.0 0.0 2.6 2 0 0 2 2 2 2 CBS domain ACP_syn_III_C PF08541.5 KKK13861.1 - 0.075 13.0 0.1 14 5.8 0.0 2.8 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal SRPRB PF09439.5 KKK13862.1 - 6.8e-26 90.5 0.2 4.2e-24 84.7 0.1 2.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.16 KKK13862.1 - 6e-08 32.1 0.0 0.0039 16.4 0.0 2.6 2 1 0 2 2 2 2 ADP-ribosylation factor family MMR_HSR1 PF01926.18 KKK13862.1 - 1.5e-06 28.1 0.0 2.3e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 KKK13862.1 - 7.1e-06 26.1 0.3 2.2e-05 24.4 0.1 1.9 2 0 0 2 2 2 1 AAA ATPase domain ABC_tran PF00005.22 KKK13862.1 - 9.7e-05 22.6 0.0 0.00016 21.9 0.0 1.4 1 0 0 1 1 1 1 ABC transporter GTP_EFTU PF00009.22 KKK13862.1 - 0.0011 18.4 0.0 0.024 14.0 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_29 PF13555.1 KKK13862.1 - 0.0013 18.2 0.1 0.0028 17.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain PduV-EutP PF10662.4 KKK13862.1 - 0.0014 18.1 0.1 0.0026 17.2 0.0 1.4 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation Sigma54_activat PF00158.21 KKK13862.1 - 0.0019 17.7 0.0 1.2 8.5 0.0 2.2 2 0 0 2 2 2 2 Sigma-54 interaction domain DUF258 PF03193.11 KKK13862.1 - 0.003 16.7 0.1 0.0068 15.6 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 KKK13862.1 - 0.01 15.9 0.1 0.02 15.0 0.1 1.6 1 1 0 1 1 1 0 AAA domain Miro PF08477.8 KKK13862.1 - 0.022 15.2 0.1 0.29 11.6 0.1 2.4 2 1 0 2 2 2 0 Miro-like protein AAA_24 PF13479.1 KKK13862.1 - 0.049 13.2 0.0 0.096 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 KKK13862.1 - 0.052 13.4 0.3 0.084 12.7 0.2 1.5 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.9 KKK13862.1 - 0.059 13.0 0.0 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_23 PF13476.1 KKK13862.1 - 0.068 13.4 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 KKK13862.1 - 0.069 13.9 0.1 0.17 12.7 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 KKK13862.1 - 0.084 13.1 0.3 0.16 12.2 0.2 1.7 1 1 0 1 1 1 0 AAA domain AAA_10 PF12846.2 KKK13862.1 - 0.092 12.1 0.3 0.15 11.4 0.2 1.3 1 0 0 1 1 1 0 AAA-like domain AAA_28 PF13521.1 KKK13862.1 - 0.11 12.3 0.2 0.18 11.7 0.2 1.3 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 KKK13862.1 - 0.12 11.5 0.0 0.26 10.4 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 KKK13862.1 - 0.16 11.4 0.0 0.29 10.5 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Septin PF00735.13 KKK13862.1 - 0.19 10.7 0.0 0.32 9.9 0.0 1.3 1 0 0 1 1 1 0 Septin AAA PF00004.24 KKK13862.1 - 0.24 11.6 1.0 0.79 9.9 0.7 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Na_Ca_ex PF01699.19 KKK13863.1 - 2.3e-22 79.1 24.0 1e-14 54.3 3.0 2.4 2 0 0 2 2 2 2 Sodium/calcium exchanger protein SlyX PF04102.7 KKK13863.1 - 0.051 13.9 13.9 0.19 12.1 1.8 3.6 3 0 0 3 3 3 0 SlyX N_methyl_2 PF13544.1 KKK13863.1 - 0.099 12.1 0.0 0.099 12.1 0.0 2.7 2 0 0 2 2 2 0 Type IV pilin N-term methylation site GFxxxE DUF3169 PF11368.3 KKK13863.1 - 0.24 10.5 5.3 0.04 13.1 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) PIG-P PF08510.7 KKK13863.1 - 0.88 9.2 4.3 4.2 7.0 0.0 3.1 2 0 0 2 2 2 0 PIG-P DUF4131 PF13567.1 KKK13863.1 - 1 8.7 6.3 8.4 5.7 0.0 3.3 2 1 0 3 3 3 0 Domain of unknown function (DUF4131) Peptidase_M76 PF09768.4 KKK13864.1 - 2.3e-73 245.3 3.1 2.7e-73 245.0 2.1 1.1 1 0 0 1 1 1 1 Peptidase M76 family SprT-like PF10263.4 KKK13864.1 - 0.35 10.5 7.0 0.089 12.4 1.6 2.2 1 1 1 2 2 2 0 SprT-like family Pkinase PF00069.20 KKK13865.1 - 3.8e-71 239.2 0.0 4.8e-71 238.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK13865.1 - 1.6e-44 151.9 0.0 2.1e-44 151.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KKK13865.1 - 1.8e-07 30.4 0.0 5.5e-07 28.8 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 KKK13865.1 - 3.8e-05 22.8 0.2 6.5e-05 22.0 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 KKK13865.1 - 0.019 14.2 0.1 0.041 13.2 0.1 1.6 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL APH PF01636.18 KKK13865.1 - 0.051 13.3 0.0 0.078 12.7 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF3237 PF11578.3 KKK13878.1 - 9.9e-23 80.1 0.0 1.1e-22 79.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) GSG-1 PF07803.6 KKK13878.1 - 0.016 14.8 0.1 0.088 12.4 0.0 1.9 1 1 1 2 2 2 0 GSG1-like protein Asn_synthase PF00733.16 KKK13879.1 - 2.4e-46 158.3 0.0 3.6e-46 157.7 0.0 1.3 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 KKK13879.1 - 4.6e-37 126.5 0.0 7.9e-37 125.7 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 KKK13879.1 - 2.5e-32 111.6 0.0 4.3e-32 110.8 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.3 KKK13879.1 - 0.00056 19.1 0.0 0.001 18.3 0.0 1.4 1 0 0 1 1 1 1 Aluminium induced protein GATase_2 PF00310.16 KKK13879.1 - 0.035 12.7 0.0 0.22 10.1 0.0 1.9 1 1 1 2 2 2 0 Glutamine amidotransferases class-II Ctr PF04145.10 KKK13880.1 - 1.8e-35 122.0 0.4 2.2e-35 121.8 0.3 1.0 1 0 0 1 1 1 1 Ctr copper transporter family DUF3707 PF12499.3 KKK13881.1 - 0.018 15.3 1.1 0.03 14.6 0.7 1.3 1 0 0 1 1 1 0 Pherophorin DUF515 PF04415.7 KKK13881.1 - 0.59 8.3 2.3 0.72 8.0 1.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Med3 PF11593.3 KKK13881.1 - 3.2 6.9 13.0 3.8 6.6 9.0 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal AATase PF07247.7 KKK13882.1 - 5.1e-28 97.8 0.0 6.6e-28 97.4 0.0 1.1 1 0 0 1 1 1 1 Alcohol acetyltransferase Condensation PF00668.15 KKK13882.1 - 6.3e-07 28.5 0.5 6.6e-06 25.1 0.0 2.1 2 0 0 2 2 2 1 Condensation domain FAD_binding_8 PF08022.7 KKK13883.1 - 7.5e-20 70.7 0.0 1.5e-19 69.7 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 KKK13883.1 - 3.9e-19 69.0 0.0 8.1e-19 68.0 0.0 1.5 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 KKK13883.1 - 2.7e-17 63.0 12.3 7e-17 61.6 8.5 1.7 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 KKK13883.1 - 0.001 19.1 0.0 0.0036 17.4 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain Abhydrolase_2 PF02230.11 KKK13884.1 - 4.9e-61 205.9 0.0 5.6e-61 205.7 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 KKK13884.1 - 4.5e-12 45.9 0.0 6.7e-12 45.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KKK13884.1 - 1.1e-08 35.3 0.0 0.0034 17.3 0.0 2.5 1 1 1 2 2 2 2 Alpha/beta hydrolase family FSH1 PF03959.8 KKK13884.1 - 6.5e-07 29.0 0.0 2.1e-06 27.3 0.0 1.8 1 1 0 1 1 1 1 Serine hydrolase (FSH1) LIP PF03583.9 KKK13884.1 - 0.00019 20.7 0.1 0.0027 16.9 0.0 2.1 2 0 0 2 2 2 1 Secretory lipase Abhydrolase_3 PF07859.8 KKK13884.1 - 0.00023 20.8 0.0 0.00038 20.0 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KKK13884.1 - 0.00027 20.2 0.0 0.02 14.1 0.0 2.3 2 0 0 2 2 2 1 Prolyl oligopeptidase family DLH PF01738.13 KKK13884.1 - 0.00045 19.5 0.0 0.00067 19.0 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family Lipase_3 PF01764.20 KKK13884.1 - 0.03 13.9 0.0 0.042 13.4 0.0 1.5 1 1 0 1 1 1 0 Lipase (class 3) Abhydro_lipase PF04083.11 KKK13884.1 - 0.088 12.1 0.0 0.36 10.2 0.0 1.9 2 0 0 2 2 2 0 Partial alpha/beta-hydrolase lipase region FSH1 PF03959.8 KKK13885.1 - 2e-36 125.4 0.0 2.4e-36 125.1 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.11 KKK13885.1 - 0.018 14.4 0.3 0.042 13.2 0.2 1.6 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 KKK13885.1 - 0.029 14.1 0.2 0.043 13.5 0.1 1.3 1 1 0 1 1 1 0 Alpha/beta hydrolase family ICL PF00463.16 KKK13886.1 - 5e-188 625.5 0.0 6.1e-188 625.2 0.0 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 KKK13886.1 - 2.8e-10 39.8 0.1 9.2e-10 38.1 0.0 1.8 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase Arg_repressor_C PF02863.13 KKK13886.1 - 0.048 13.1 0.0 0.093 12.2 0.0 1.4 1 0 0 1 1 1 0 Arginine repressor, C-terminal domain EutQ PF06249.7 KKK13887.1 - 5.5e-12 45.4 0.0 6.8e-12 45.1 0.0 1.1 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ Cupin_3 PF05899.7 KKK13887.1 - 4.5e-08 32.3 0.1 6.4e-08 31.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_2 PF07883.6 KKK13887.1 - 1.5e-05 24.4 0.0 2.1e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Cupin domain Cupin_6 PF12852.2 KKK13887.1 - 0.0047 16.5 0.0 0.0054 16.3 0.0 1.1 1 0 0 1 1 1 1 Cupin Pirin PF02678.11 KKK13887.1 - 0.052 13.4 0.0 0.11 12.4 0.0 1.4 1 1 0 1 1 1 0 Pirin SH3BGR PF04908.10 KKK13887.1 - 0.059 13.3 0.0 0.12 12.2 0.0 1.6 2 0 0 2 2 2 0 SH3-binding, glutamic acid-rich protein Fungal_trans_2 PF11951.3 KKK13888.1 - 1.4e-60 204.9 2.1 1.9e-60 204.4 1.5 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF1687 PF07955.6 KKK13889.1 - 1.2e-08 35.0 0.0 6.4e-08 32.6 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1687) Pkinase PF00069.20 KKK13890.1 - 5e-56 189.7 0.0 3.3e-55 187.0 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK13890.1 - 3.3e-27 95.2 0.1 1.8e-19 69.8 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.19 KKK13890.1 - 6.5e-07 29.7 0.1 6.5e-07 29.7 0.1 2.0 2 0 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.1 KKK13890.1 - 0.00055 18.9 0.1 0.0039 16.2 0.0 2.1 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 KKK13890.1 - 0.00089 19.0 0.0 0.13 11.9 0.0 2.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 KKK13890.1 - 0.08 12.0 0.4 0.2 10.6 0.0 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF605 PF04652.11 KKK13890.1 - 9.1 5.5 9.9 13 5.0 6.9 1.2 1 0 0 1 1 1 0 Vta1 like APH PF01636.18 KKK13893.1 - 6.3e-09 35.9 0.3 7.5e-06 25.8 0.1 2.3 2 0 0 2 2 2 2 Phosphotransferase enzyme family Choline_kinase PF01633.15 KKK13893.1 - 0.031 13.8 0.1 0.069 12.7 0.1 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase Peptidase_C13 PF01650.13 KKK13894.1 - 7.5e-06 25.4 0.0 1.2e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase C13 family Mito_carr PF00153.22 KKK13896.1 - 4.1e-28 96.9 1.9 2.7e-15 55.8 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Atg8 PF02991.11 KKK13897.1 - 2.1e-47 159.3 0.6 2.7e-47 158.9 0.4 1.1 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.8 KKK13897.1 - 4.2e-05 23.6 0.1 6e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Coprogen_oxidas PF01218.13 KKK13898.1 - 1.6e-110 368.3 0.0 2.1e-110 367.9 0.0 1.1 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase HOOK PF05622.7 KKK13899.1 - 9.9e-24 83.1 23.2 9.9e-24 83.1 16.1 2.6 2 0 0 2 2 2 2 HOOK protein DUF4164 PF13747.1 KKK13899.1 - 0.0099 15.9 1.9 0.0099 15.9 1.3 6.9 5 3 1 7 7 7 1 Domain of unknown function (DUF4164) CENP-F_leu_zip PF10473.4 KKK13899.1 - 0.02 14.7 71.2 0.12 12.2 3.8 6.5 4 1 2 6 6 6 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TPR_MLP1_2 PF07926.7 KKK13899.1 - 2.1 8.0 0.0 2.1 8.0 0.0 7.6 4 2 3 7 7 7 0 TPR/MLP1/MLP2-like protein KIP1 PF07765.7 KKK13899.1 - 4.5 7.1 8.6 2.7 7.8 0.1 4.7 4 1 2 6 6 6 0 KIP1-like protein Inhibitor_I9 PF05922.11 KKK13900.1 - 0.0026 18.3 0.0 0.0028 18.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase inhibitor I9 CFIA_Pcf11 PF11526.3 KKK13901.1 - 0.0025 17.8 0.1 0.0057 16.7 0.1 1.6 1 0 0 1 1 1 1 Subunit of cleavage factor IA Pcf11 CTD_bind PF04818.8 KKK13901.1 - 0.0054 16.9 0.0 0.016 15.4 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase II-binding domain. RRN7 PF11781.3 KKK13901.1 - 0.0077 15.7 2.6 0.025 14.0 0.3 2.2 2 0 0 2 2 2 1 RNA polymerase I-specific transcription initiation factor Rrn7 VHS PF00790.14 KKK13901.1 - 0.05 13.2 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 VHS domain zf-C2H2_4 PF13894.1 KKK13901.1 - 0.52 10.7 3.0 13 6.4 0.1 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-ISL3 PF14690.1 KKK13901.1 - 0.58 10.2 2.3 1.2 9.2 0.3 2.3 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zf-C2HC_2 PF13913.1 KKK13901.1 - 0.77 9.5 6.7 2.5 7.8 0.1 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type GFO_IDH_MocA PF01408.17 KKK13902.1 - 2.9e-18 66.5 0.1 4.5e-18 65.9 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 KKK13902.1 - 0.0053 16.5 0.0 0.011 15.4 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain MitMem_reg PF13012.1 KKK13903.1 - 7.1e-40 135.6 0.1 1.5e-39 134.6 0.0 1.6 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function JAB PF01398.16 KKK13903.1 - 4.2e-29 100.6 0.1 1.8e-28 98.5 0.0 1.9 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease ADK PF00406.17 KKK13904.1 - 1.9e-60 203.1 0.1 2.4e-60 202.8 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 KKK13904.1 - 5.4e-15 54.7 0.0 1.3e-14 53.4 0.0 1.7 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_33 PF13671.1 KKK13904.1 - 3.2e-05 23.8 0.0 5.4e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KKK13904.1 - 0.00013 22.7 0.0 0.00026 21.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KKK13904.1 - 0.0006 18.9 0.0 0.0011 18.1 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.1 KKK13904.1 - 0.0027 18.0 0.0 0.005 17.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain Methyltransf_11 PF08241.7 KKK13905.1 - 6.2e-16 58.6 0.0 1.5e-15 57.4 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 KKK13905.1 - 2.7e-08 33.7 0.0 4.8e-08 32.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KKK13905.1 - 6e-08 32.9 0.0 1.3e-07 31.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KKK13905.1 - 7e-06 26.4 0.0 2.7e-05 24.5 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KKK13905.1 - 1.3e-05 24.8 0.0 2.3e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KKK13905.1 - 0.00026 21.5 0.0 0.0009 19.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_9 PF08003.6 KKK13905.1 - 0.031 12.9 0.1 0.21 10.2 0.0 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1698) DnaB_bind PF10410.4 KKK13905.1 - 0.052 13.5 0.0 0.084 12.8 0.0 1.4 1 0 0 1 1 1 0 DnaB-helicase binding domain of primase MetW PF07021.7 KKK13905.1 - 0.096 12.0 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Dynamin_M PF01031.15 KKK13939.1 - 1.9e-105 351.8 1.0 2.6e-105 351.4 0.1 1.6 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.18 KKK13939.1 - 2.5e-56 190.0 0.1 5e-56 189.1 0.0 1.5 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 KKK13939.1 - 1.3e-28 98.7 4.5 1.3e-28 98.7 3.1 2.2 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 KKK13939.1 - 0.00015 21.7 0.2 0.0013 18.6 0.1 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF2226 PF09987.4 KKK13939.1 - 0.0022 17.1 0.7 0.29 10.2 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized protein conserved in archaea (DUF2226) Miro PF08477.8 KKK13939.1 - 0.01 16.3 0.0 0.064 13.7 0.0 2.2 2 0 0 2 2 2 0 Miro-like protein FeoB_N PF02421.13 KKK13939.1 - 0.092 12.0 0.4 17 4.6 0.0 2.7 3 0 0 3 3 3 0 Ferrous iron transport protein B CN_hydrolase PF00795.17 KKK13940.1 - 5.9e-31 107.2 0.1 7.9e-31 106.8 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Glyco_trans_2_3 PF13632.1 KKK13941.1 - 4.9e-35 120.9 6.5 4.9e-35 120.9 4.5 2.0 1 1 1 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 KKK13941.1 - 0.00012 21.9 0.0 0.00064 19.5 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Tir_receptor_C PF07489.6 KKK13941.1 - 0.075 12.7 0.2 0.13 11.9 0.1 1.3 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus Glycos_transf_2 PF00535.21 KKK13941.1 - 0.13 11.8 0.0 0.46 10.1 0.0 1.9 1 1 0 1 1 1 0 Glycosyl transferase family 2 TrkH PF02386.11 KKK13942.1 - 2.1e-119 398.2 18.6 3.1e-118 394.4 6.2 2.1 2 0 0 2 2 2 2 Cation transport protein WD40 PF00400.27 KKK13943.1 - 3.8e-33 112.1 9.2 4.6e-07 29.4 0.1 5.9 5 0 0 5 5 5 5 WD domain, G-beta repeat CLTH PF10607.4 KKK13943.1 - 0.012 15.3 0.0 0.02 14.5 0.0 1.3 1 0 0 1 1 1 0 CTLH/CRA C-terminal to LisH motif domain Cytochrom_D1 PF02239.11 KKK13943.1 - 0.077 11.2 0.1 0.98 7.6 0.0 2.2 2 0 0 2 2 2 0 Cytochrome D1 heme domain ATP-synt_ab PF00006.20 KKK13944.1 - 3.6e-115 382.8 0.0 6.2e-115 382.1 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 KKK13944.1 - 1.8e-16 60.6 0.4 3e-16 59.8 0.3 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 KKK13944.1 - 2.7e-15 56.3 1.8 5.8e-15 55.2 1.2 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain DUF1180 PF06679.7 KKK13944.1 - 0.022 14.6 0.7 0.038 13.8 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) NIF PF03031.13 KKK13953.1 - 6.2e-24 84.4 0.0 1.2e-23 83.5 0.0 1.5 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase MFS_1 PF07690.11 KKK13956.1 - 1.9e-21 76.1 41.0 1.9e-21 76.1 28.4 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Methyltransf_2 PF00891.13 KKK13957.1 - 6.5e-16 58.2 0.0 2.5e-15 56.3 0.0 1.8 1 1 1 2 2 2 1 O-methyltransferase Methyltransf_23 PF13489.1 KKK13957.1 - 3.9e-05 23.4 0.0 6.2e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Transp_cyt_pur PF02133.10 KKK13959.1 - 1.6e-29 102.7 31.8 1e-28 100.1 22.0 2.1 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Cation_efflux PF01545.16 KKK13959.1 - 0.00013 21.1 0.0 0.00031 19.9 0.0 1.8 1 1 1 2 2 2 1 Cation efflux family p450 PF00067.17 KKK13960.1 - 1.4e-62 211.7 0.0 1.8e-62 211.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 KKK13961.1 - 3.1e-13 49.1 22.9 3e-09 36.0 8.9 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily ABC_tran PF00005.22 KKK13962.1 - 1.8e-52 177.2 0.0 3.9e-30 104.9 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 KKK13962.1 - 3e-31 108.8 15.3 3.4e-17 62.7 4.8 2.6 2 1 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.14 KKK13962.1 - 1.1e-08 34.5 0.0 0.0011 18.3 0.1 3.7 2 2 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 KKK13962.1 - 9.3e-07 29.0 0.2 0.039 13.9 0.1 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.1 KKK13962.1 - 1.5e-06 28.4 0.3 0.26 11.2 0.0 4.4 3 1 1 4 4 4 1 AAA domain AAA_25 PF13481.1 KKK13962.1 - 6e-06 25.7 0.1 0.099 12.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 KKK13962.1 - 7.7e-06 25.1 0.1 0.021 14.0 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 KKK13962.1 - 1.1e-05 25.5 0.8 0.13 12.3 0.0 3.5 2 1 0 2 2 2 2 AAA domain AAA_23 PF13476.1 KKK13962.1 - 2.2e-05 24.9 0.1 0.014 15.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 KKK13962.1 - 3e-05 23.6 0.2 0.079 12.3 0.0 3.2 2 1 0 3 3 3 1 AAA-like domain Zeta_toxin PF06414.7 KKK13962.1 - 0.00043 19.4 0.3 0.23 10.5 0.0 2.3 2 0 0 2 2 2 2 Zeta toxin AAA_17 PF13207.1 KKK13962.1 - 0.00057 20.6 0.0 0.13 13.0 0.0 2.9 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 KKK13962.1 - 0.00064 19.6 0.3 0.28 11.1 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_29 PF13555.1 KKK13962.1 - 0.00084 18.8 0.3 1.4 8.5 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 KKK13962.1 - 0.0014 18.1 0.0 2.1 7.7 0.0 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family UPF0079 PF02367.12 KKK13962.1 - 0.0035 16.9 0.3 0.069 12.7 0.0 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 NACHT PF05729.7 KKK13962.1 - 0.0071 16.0 0.8 0.88 9.2 0.1 2.5 2 0 0 2 2 2 1 NACHT domain ATP-synt_ab PF00006.20 KKK13962.1 - 0.0077 15.7 0.0 1.2 8.5 0.0 2.3 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain IstB_IS21 PF01695.12 KKK13962.1 - 0.0092 15.4 0.1 0.22 10.8 0.0 2.7 2 0 0 2 2 2 1 IstB-like ATP binding protein T2SE PF00437.15 KKK13962.1 - 0.0094 14.8 0.0 2 7.2 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein Miro PF08477.8 KKK13962.1 - 0.013 15.9 0.2 6.7 7.2 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein AAA_18 PF13238.1 KKK13962.1 - 0.017 15.3 0.0 6.6 7.0 0.0 3.1 3 0 0 3 3 2 0 AAA domain cobW PF02492.14 KKK13962.1 - 0.02 14.3 0.9 0.4 10.1 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.1 KKK13962.1 - 0.02 14.4 0.0 6.1 6.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 KKK13962.1 - 0.021 15.0 0.2 8.6 6.5 0.0 3.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.4 KKK13962.1 - 0.022 13.7 0.2 0.28 10.1 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) RNA_helicase PF00910.17 KKK13962.1 - 0.031 14.4 0.0 9.1 6.5 0.0 2.9 3 0 0 3 3 2 0 RNA helicase KaiC PF06745.8 KKK13962.1 - 0.033 13.2 0.0 1.9 7.5 0.0 2.5 2 0 0 2 2 2 0 KaiC MobB PF03205.9 KKK13962.1 - 0.047 13.4 0.2 2.1 8.0 0.0 2.8 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B DUF87 PF01935.12 KKK13962.1 - 0.057 13.2 5.3 0.093 12.5 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function DUF87 SbcCD_C PF13558.1 KKK13962.1 - 0.068 13.0 0.0 18 5.2 0.0 3.2 3 0 0 3 3 3 0 Putative exonuclease SbcCD, C subunit APS_kinase PF01583.15 KKK13962.1 - 0.1 12.2 0.5 0.23 11.0 0.0 1.8 2 0 0 2 2 2 0 Adenylylsulphate kinase TrwB_AAD_bind PF10412.4 KKK13962.1 - 0.19 10.3 0.9 5.2 5.5 0.1 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Hemerythrin PF01814.18 KKK13963.1 - 8.5e-11 42.1 0.6 1.3e-10 41.5 0.4 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain ketoacyl-synt PF00109.21 KKK13964.1 - 1.7e-64 217.7 0.0 4e-64 216.5 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 KKK13964.1 - 1.4e-57 195.4 0.3 2.2e-57 194.8 0.2 1.3 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 KKK13964.1 - 8.8e-56 189.2 0.0 1.7e-55 188.2 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.5 KKK13964.1 - 1.2e-53 181.4 0.6 7.6e-53 178.8 0.2 2.3 2 0 0 2 2 2 1 KR domain adh_short PF00106.20 KKK13964.1 - 3.3e-39 134.4 1.2 2.2e-38 131.8 0.0 2.9 4 0 0 4 4 3 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 KKK13964.1 - 6.5e-31 106.6 0.1 1.7e-30 105.3 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 KKK13964.1 - 4.6e-19 68.2 0.3 3.3e-18 65.5 0.0 2.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.7 KKK13964.1 - 1.7e-17 63.6 0.0 6.5e-17 61.8 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KKK13964.1 - 3.7e-15 56.0 0.0 8.4e-15 54.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 KKK13964.1 - 3.3e-12 47.4 0.0 2.5e-11 44.5 0.0 2.6 2 0 0 2 2 1 1 Zinc-binding dehydrogenase Methyltransf_31 PF13847.1 KKK13964.1 - 7.1e-10 38.6 0.0 4.3e-09 36.1 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KKK13964.1 - 5.6e-09 36.5 0.0 3e-08 34.2 0.0 2.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KKK13964.1 - 6.4e-09 36.1 0.0 2e-08 34.6 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 KKK13964.1 - 5e-08 33.1 0.1 1.3e-07 31.7 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site ADH_N PF08240.7 KKK13964.1 - 1e-07 31.6 0.1 9.6e-07 28.5 0.0 2.4 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Ubie_methyltran PF01209.13 KKK13964.1 - 2.2e-05 23.7 0.0 4.9e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Thiolase_N PF00108.18 KKK13964.1 - 4.3e-05 22.6 0.2 8.9e-05 21.5 0.1 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_16 PF10294.4 KKK13964.1 - 0.0023 17.4 0.0 0.026 13.9 0.0 2.6 3 0 0 3 3 3 1 Putative methyltransferase NodS PF05401.6 KKK13964.1 - 0.0059 16.0 0.0 0.016 14.5 0.0 1.7 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_26 PF13659.1 KKK13964.1 - 0.019 14.9 0.0 0.055 13.5 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 KKK13964.1 - 0.078 12.3 0.0 0.19 11.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase small domain Glyco_hydro_45 PF02015.11 KKK13965.1 - 3.3e-10 40.3 15.7 1e-09 38.7 10.9 1.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 45 DPBB_1 PF03330.13 KKK13965.1 - 2.1e-08 34.0 1.9 2.6e-08 33.7 0.1 1.8 2 0 0 2 2 2 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Glyco_hydro_43 PF04616.9 KKK13966.1 - 9.5e-65 218.5 2.9 1.3e-64 218.0 2.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Trp_DMAT PF11991.3 KKK13967.1 - 5.3e-89 298.9 0.0 1.7e-45 155.8 0.0 2.1 1 1 1 2 2 2 2 Tryptophan dimethylallyltransferase TyeA PF09059.5 KKK13967.1 - 0.062 13.2 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 TyeA UXS1_N PF11803.3 KKK13967.1 - 0.13 12.0 0.0 0.36 10.6 0.0 1.7 2 0 0 2 2 2 0 UDP-glucuronate decarboxylase N-terminal CRAL_TRIO PF00650.15 KKK13968.1 - 6.8e-38 129.6 0.0 1.1e-37 128.9 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 KKK13968.1 - 2.6e-07 30.6 0.0 4.8e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.10 KKK13968.1 - 0.0031 17.6 0.1 0.018 15.1 0.0 2.3 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain FAD_binding_3 PF01494.14 KKK13969.1 - 1.3e-25 90.2 1.0 3.7e-16 59.1 0.1 2.3 2 1 0 2 2 2 2 FAD binding domain FAD_binding_2 PF00890.19 KKK13969.1 - 0.00011 21.1 0.4 0.00019 20.4 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.19 KKK13969.1 - 0.00028 19.9 0.3 0.0011 17.9 0.1 1.8 1 1 0 2 2 2 1 FAD dependent oxidoreductase TrkA_N PF02254.13 KKK13969.1 - 0.0017 18.3 0.1 0.0042 17.0 0.0 1.6 2 0 0 2 2 2 1 TrkA-N domain Lycopene_cycl PF05834.7 KKK13969.1 - 0.0019 17.1 1.0 0.0055 15.6 0.0 2.1 2 1 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 KKK13969.1 - 0.0053 16.8 0.6 0.031 14.3 0.0 2.3 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KKK13969.1 - 0.0054 17.1 0.0 0.13 12.6 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KKK13969.1 - 0.0074 16.2 0.1 0.028 14.4 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain PALP PF00291.20 KKK13969.1 - 0.02 14.1 0.0 0.034 13.3 0.0 1.4 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme Thi4 PF01946.12 KKK13969.1 - 0.025 13.6 0.0 0.045 12.8 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox_2 PF07992.9 KKK13969.1 - 0.05 13.4 0.0 0.091 12.6 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 KKK13969.1 - 0.062 12.9 0.0 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain IlvN PF07991.7 KKK13969.1 - 0.08 12.3 0.0 0.16 11.2 0.0 1.6 1 1 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain CPSase_L_chain PF00289.17 KKK13969.1 - 0.12 12.5 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, N-terminal domain MFS_1 PF07690.11 KKK13970.1 - 3.2e-29 101.7 71.5 3.4e-22 78.6 23.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1279 PF06916.8 KKK13970.1 - 0.018 15.3 1.0 0.018 15.3 0.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1279) Abhydrolase_3 PF07859.8 KKK13971.1 - 4.5e-46 157.0 0.0 5.7e-46 156.7 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 KKK13971.1 - 3.6e-10 39.1 1.6 1.1e-09 37.5 1.1 1.7 1 1 0 1 1 1 1 Carboxylesterase family DUF2424 PF10340.4 KKK13971.1 - 0.18 10.3 0.0 0.28 9.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) AMP-binding PF00501.23 KKK13972.1 - 3.6e-86 289.1 0.0 4.5e-86 288.8 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KKK13972.1 - 8.5e-14 52.2 0.0 2.3e-13 50.8 0.0 1.8 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Pyridoxal_deC PF00282.14 KKK13973.1 - 2.7e-68 230.1 0.0 1.1e-54 185.3 0.0 2.1 2 0 0 2 2 2 2 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.16 KKK13973.1 - 5.3e-08 32.3 0.0 8.2e-08 31.7 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 KKK13973.1 - 2.5e-07 29.7 0.0 4.6e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Condensation PF00668.15 KKK13974.1 - 6.5e-84 281.3 1.0 1.8e-33 115.6 0.0 3.9 3 0 0 3 3 3 3 Condensation domain AMP-binding PF00501.23 KKK13974.1 - 8.5e-83 278.0 0.0 1.2e-82 277.5 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.20 KKK13974.1 - 4.1e-22 78.2 0.5 3.5e-12 46.3 0.1 3.1 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding_C PF13193.1 KKK13974.1 - 0.00046 21.0 0.0 0.0012 19.7 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain E2 PF08199.6 KKK13974.1 - 0.37 10.4 0.2 0.84 9.2 0.1 1.6 1 0 0 1 1 1 0 Bacteriophage E2-like protein Zn_clus PF00172.13 KKK13975.1 - 6.2e-08 32.4 6.2 1.1e-07 31.5 4.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF268 PF03269.9 KKK13975.1 - 0.11 12.0 0.1 0.51 9.9 0.0 1.9 2 0 0 2 2 2 0 Caenorhabditis protein of unknown function, DUF268 Mito_fiss_reg PF05308.6 KKK13975.1 - 0.14 11.4 4.5 0.034 13.5 0.9 1.5 2 0 0 2 2 2 0 Mitochondrial fission regulator CAP_N PF01213.14 KKK13975.1 - 0.23 10.6 4.8 0.23 10.6 1.7 1.9 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal p450 PF00067.17 KKK13976.1 - 5.9e-77 259.1 0.0 6.5e-77 259.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_25 PF13649.1 KKK13977.1 - 1.5e-08 34.9 0.0 2.7e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KKK13977.1 - 0.0012 18.5 0.0 0.0017 18.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KKK13977.1 - 0.0019 17.8 0.0 0.0025 17.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KKK13977.1 - 0.014 15.8 0.0 0.024 15.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain FmrO PF07091.6 KKK13977.1 - 0.035 13.1 0.0 0.06 12.3 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) Pox_MCEL PF03291.11 KKK13977.1 - 0.056 12.3 0.0 0.17 10.7 0.0 1.7 1 1 0 1 1 1 0 mRNA capping enzyme Aldedh PF00171.17 KKK13979.1 - 2.7e-09 35.9 0.1 3.3e-05 22.4 0.0 2.4 2 1 0 2 2 2 2 Aldehyde dehydrogenase family MitoNEET_N PF10660.4 KKK13979.1 - 0.063 13.1 0.4 0.16 11.8 0.3 1.6 1 0 0 1 1 1 0 Iron-containing outer mitochondrial membrane protein N-terminus AA_permease PF00324.16 KKK13980.1 - 1.4e-51 175.3 43.9 2.4e-30 105.3 15.3 3.0 2 1 0 2 2 2 2 Amino acid permease AA_permease_2 PF13520.1 KKK13980.1 - 1.8e-22 79.4 43.2 4.5e-22 78.1 29.1 2.2 1 1 0 1 1 1 1 Amino acid permease Nnf1 PF03980.9 KKK13980.1 - 0.22 11.4 0.2 0.4 10.6 0.1 1.3 1 0 0 1 1 1 0 Nnf1 CP_ATPgrasp_2 PF14403.1 KKK13981.1 - 2.5e-08 32.9 0.0 0.00097 17.8 0.0 2.2 2 0 0 2 2 2 2 Circularly permuted ATP-grasp type 2 TauD PF02668.11 KKK13982.1 - 5.3e-20 72.1 1.5 5.6e-19 68.8 0.4 2.4 3 0 0 3 3 3 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.5 KKK13982.1 - 0.00068 18.6 0.0 0.0012 17.7 0.0 1.4 1 0 0 1 1 1 1 CsiD AMP-binding PF00501.23 KKK13982.1 - 0.042 12.2 0.0 0.066 11.6 0.0 1.2 1 0 0 1 1 1 0 AMP-binding enzyme AAT PF03417.11 KKK13984.1 - 3.3e-27 95.4 0.0 4.4e-27 95.0 0.0 1.1 1 0 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase NAAA-beta PF15508.1 KKK13984.1 - 0.0009 19.5 0.0 0.0017 18.6 0.0 1.4 1 0 0 1 1 1 1 beta subunit of N-acylethanolamine-hydrolyzing acid amidase Pkinase PF00069.20 KKK13985.1 - 2.3e-24 85.9 0.0 4.2e-24 85.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK13985.1 - 8.7e-15 54.4 0.0 1.8e-14 53.4 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase CorA PF01544.13 KKK13986.1 - 0.0041 16.1 4.8 0.0041 16.1 3.3 2.1 2 1 0 2 2 2 1 CorA-like Mg2+ transporter protein SLAC1 PF03595.12 KKK13986.1 - 0.022 13.4 0.8 0.033 12.8 0.6 1.1 1 0 0 1 1 1 0 Voltage-dependent anion channel ACOX PF01756.14 KKK13988.1 - 1.4e-36 125.5 0.0 3.8e-36 124.2 0.0 1.6 2 0 0 2 2 2 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.1 KKK13988.1 - 1.3e-26 93.3 0.2 2.5e-26 92.4 0.1 1.5 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.14 KKK13988.1 - 5e-12 45.1 0.6 1.7e-11 43.4 0.1 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.19 KKK13988.1 - 8.8e-06 25.8 0.6 0.0027 17.8 0.4 2.5 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain DIOX_N PF14226.1 KKK13989.1 - 1.7e-27 96.2 0.1 2.6e-27 95.6 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KKK13989.1 - 1.9e-22 79.4 0.0 3.7e-22 78.4 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily LigB PF02900.13 KKK13990.1 - 3.2e-23 82.0 0.2 3.8e-23 81.8 0.2 1.1 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase Nsp3_PL2pro PF12124.3 KKK13990.1 - 0.11 12.0 0.0 0.25 10.9 0.0 1.5 1 0 0 1 1 1 0 Coronavirus polyprotein cleavage domain Fungal_trans PF04082.13 KKK13991.1 - 2.5e-13 49.4 1.8 4.7e-13 48.6 1.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK13991.1 - 4.1e-06 26.6 12.6 7.5e-06 25.7 8.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2 PF00096.21 KKK13991.1 - 0.0035 17.5 1.5 0.0035 17.5 1.1 2.8 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KKK13991.1 - 0.0049 17.1 0.8 0.0049 17.1 0.6 2.6 2 0 0 2 2 2 1 C2H2-type zinc finger Methyltransf_23 PF13489.1 KKK13992.1 - 1.5e-22 80.0 0.0 2.1e-22 79.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KKK13992.1 - 9.7e-14 51.6 0.0 2.2e-13 50.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KKK13992.1 - 9.9e-12 44.6 0.0 7.2e-11 41.8 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KKK13992.1 - 6.7e-10 39.5 0.0 1.4e-08 35.3 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KKK13992.1 - 4.2e-09 36.7 0.0 3.3e-08 33.9 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KKK13992.1 - 2.8e-07 29.8 0.0 0.0028 16.8 0.0 2.1 2 0 0 2 2 2 2 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 KKK13992.1 - 3.7e-05 23.7 0.0 0.00022 21.2 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 KKK13992.1 - 7.8e-05 21.8 0.0 0.00014 21.0 0.0 1.4 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.9 KKK13992.1 - 0.00037 19.9 0.0 0.005 16.2 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_25 PF13649.1 KKK13992.1 - 0.00061 20.1 0.0 0.0038 17.5 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 KKK13992.1 - 0.0027 16.8 0.0 0.015 14.3 0.0 2.0 2 0 0 2 2 2 1 Putative methyltransferase FtsJ PF01728.14 KKK13992.1 - 0.011 15.7 0.0 0.04 13.8 0.0 1.8 1 1 1 2 2 2 0 FtsJ-like methyltransferase PrmA PF06325.8 KKK13992.1 - 0.019 14.0 0.0 0.031 13.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_2 PF00891.13 KKK13992.1 - 0.026 13.7 0.0 0.089 11.9 0.0 1.9 1 1 1 2 2 2 0 O-methyltransferase Methyltransf_16 PF10294.4 KKK13992.1 - 0.12 11.8 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Peptidase_S15 PF02129.13 KKK13993.1 - 1.2e-39 136.3 0.5 1.7e-39 135.9 0.4 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.5 KKK13993.1 - 1.4e-38 132.9 0.3 2.4e-38 132.2 0.2 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Abhydrolase_6 PF12697.2 KKK13993.1 - 1.3e-05 25.2 0.3 2.2e-05 24.4 0.2 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KKK13993.1 - 3.3e-05 23.6 0.0 8e-05 22.4 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KKK13993.1 - 0.0035 17.1 0.0 0.0091 15.8 0.0 1.7 1 0 0 1 1 1 1 Putative lysophospholipase Voltage_CLC PF00654.15 KKK13997.1 - 2.3e-92 309.7 20.5 2.3e-92 309.7 14.2 1.9 2 0 0 2 2 2 1 Voltage gated chloride channel Lipase_GDSL_2 PF13472.1 KKK13998.1 - 5.4e-24 85.2 0.0 6.6e-24 85.0 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 KKK13998.1 - 1.2e-18 67.7 0.0 1.5e-18 67.5 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase G-patch_2 PF12656.2 KKK13998.1 - 0.14 11.9 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 DExH-box splicing factor binding site Pectate_lyase PF03211.8 KKK13999.1 - 3e-77 258.8 2.0 3.6e-77 258.5 1.4 1.0 1 0 0 1 1 1 1 Pectate lyase Isochorismatase PF00857.15 KKK14000.1 - 2.5e-20 73.1 0.0 3.5e-20 72.6 0.0 1.2 1 0 0 1 1 1 1 Isochorismatase family RVP_2 PF08284.6 KKK14001.1 - 0.028 14.3 0.0 0.064 13.1 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease Glyco_hydro_16 PF00722.16 KKK14009.1 - 2.5e-32 111.6 1.9 3.5e-32 111.1 1.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 RTC PF01137.16 KKK14011.1 - 9.2e-37 126.0 0.0 1.2e-36 125.6 0.0 1.1 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase DUF2439 PF10382.4 KKK14012.1 - 7.7e-29 99.7 0.4 1.2e-28 99.1 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) SH3_9 PF14604.1 KKK14013.1 - 2.1e-15 56.0 0.2 5.1e-15 54.7 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain BAR PF03114.13 KKK14013.1 - 4.5e-13 49.2 1.0 6.9e-13 48.6 0.3 1.6 1 1 1 2 2 2 1 BAR domain SH3_1 PF00018.23 KKK14013.1 - 4.8e-13 48.2 0.1 8.8e-13 47.4 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KKK14013.1 - 7.3e-12 44.5 0.1 1.6e-11 43.4 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain DUF4363 PF14276.1 KKK14013.1 - 0.04 13.6 0.5 2.7 7.7 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4363) DUF4541 PF15074.1 KKK14013.1 - 0.28 11.7 3.5 0.6 10.6 2.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4541) zf-CCCH PF00642.19 KKK14014.1 - 4.6e-08 32.5 2.1 8.7e-08 31.6 1.4 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_3 PF13920.1 KKK14014.1 - 1.2e-07 31.2 4.3 2.1e-07 30.4 3.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KKK14014.1 - 1.9e-07 30.9 10.3 3.3e-07 30.2 7.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KKK14014.1 - 1.8e-06 27.5 8.7 2.9e-06 26.9 6.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KKK14014.1 - 6.9e-06 25.6 10.6 1.2e-05 24.8 7.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KKK14014.1 - 8e-06 25.5 7.1 1.4e-05 24.7 4.9 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.1 KKK14014.1 - 0.011 15.5 9.1 0.025 14.4 6.3 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Rep_Org_C PF06926.6 KKK14014.1 - 0.022 14.8 0.0 0.054 13.5 0.0 1.7 1 0 0 1 1 1 0 Putative replisome organiser protein C-terminus zf-Nse PF11789.3 KKK14014.1 - 0.056 12.9 2.4 0.1 12.0 1.6 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 KKK14014.1 - 0.12 12.1 5.4 0.28 10.9 3.7 1.6 1 0 0 1 1 1 0 RING-type zinc-finger Cript PF10235.4 KKK14014.1 - 1.2 9.5 6.2 0.58 10.5 2.3 2.0 2 0 0 2 2 2 0 Microtubule-associated protein CRIPT Mcp5_PH PF12814.2 KKK14015.1 - 3.6e-43 146.4 0.3 7.1e-43 145.4 0.2 1.5 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology WHIM2 PF15613.1 KKK14015.1 - 0.071 13.0 0.3 12 5.9 0.5 2.7 2 0 0 2 2 2 0 WSTF, HB1, Itc1p, MBD9 motif 2 DUF846 PF05832.7 KKK14015.1 - 1.2 8.8 0.1 2 8.1 0.1 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF846) DUF3431 PF11913.3 KKK14016.1 - 3e-89 298.3 0.5 4.1e-89 297.8 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) Asp PF00026.18 KKK14027.1 - 1.1e-47 162.8 2.2 1.4e-47 162.4 1.5 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 KKK14027.1 - 1.6e-05 25.2 0.3 1.5 9.3 0.0 3.7 3 0 0 3 3 3 3 Aspartyl protease TAXi_C PF14541.1 KKK14027.1 - 0.00074 19.0 0.1 0.0057 16.2 0.0 2.2 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal MHC_I_C PF06623.6 KKK14027.1 - 0.079 12.4 1.1 11 5.5 0.0 2.5 2 0 0 2 2 2 0 MHC_I C-terminus Glyco_hydro_43 PF04616.9 KKK14028.1 - 3.3e-22 78.9 0.8 1.4e-21 76.8 0.5 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 YIF1 PF03878.10 KKK14039.1 - 1.2e-76 257.0 3.0 1.5e-76 256.7 2.1 1.1 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.12 KKK14039.1 - 1e-05 25.0 6.2 1e-05 25.0 4.3 1.8 2 0 0 2 2 2 1 Yip1 domain SRP-alpha_N PF04086.8 KKK14040.1 - 2e-84 283.2 0.0 2.8e-84 282.8 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54 PF00448.17 KKK14040.1 - 3.1e-50 170.3 0.0 5.2e-50 169.6 0.0 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.14 KKK14040.1 - 8.5e-08 32.1 0.1 2.5e-07 30.6 0.1 1.8 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain ArgK PF03308.11 KKK14040.1 - 1.3e-05 24.0 0.0 2.5e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 ArgK protein CbiA PF01656.18 KKK14040.1 - 1.4e-05 24.5 0.1 2.9e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_30 PF13604.1 KKK14040.1 - 6.4e-05 22.6 0.0 0.00013 21.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_10 PF12846.2 KKK14040.1 - 0.0027 17.1 0.1 0.021 14.2 0.0 2.2 2 0 0 2 2 2 1 AAA-like domain MobB PF03205.9 KKK14040.1 - 0.0042 16.7 0.0 0.0097 15.6 0.0 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B Fer4_NifH PF00142.13 KKK14040.1 - 0.029 13.5 0.0 0.051 12.7 0.0 1.4 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_21 PF13304.1 KKK14040.1 - 0.068 13.1 0.7 0.3 11.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 KKK14040.1 - 0.07 13.1 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.1 KKK14040.1 - 0.13 12.3 0.0 0.81 9.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 KKK14040.1 - 0.15 12.0 0.3 0.9 9.4 0.0 2.4 3 0 0 3 3 3 0 AAA domain MFS_1 PF07690.11 KKK14041.1 - 1.7e-40 138.8 44.4 1.6e-34 119.1 11.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KKK14041.1 - 3.5e-11 42.3 15.0 7.4e-11 41.2 0.4 2.6 2 1 0 3 3 3 2 Sugar (and other) transporter MFS_2 PF13347.1 KKK14041.1 - 5e-10 38.3 0.0 1.3e-05 23.7 0.6 3.6 1 1 3 4 4 4 2 MFS/sugar transport protein MFS_1_like PF12832.2 KKK14041.1 - 0.002 17.8 3.1 0.013 15.2 0.0 3.3 3 0 0 3 3 3 1 MFS_1 like family TRI12 PF06609.8 KKK14041.1 - 0.003 15.8 1.0 0.0048 15.1 0.7 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Folate_carrier PF01770.13 KKK14041.1 - 0.043 12.3 0.8 0.06 11.8 0.0 1.6 2 0 0 2 2 2 0 Reduced folate carrier TPR_12 PF13424.1 KKK14042.1 - 5.7e-25 87.0 13.1 1e-10 41.4 2.2 5.6 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_10 PF13374.1 KKK14042.1 - 2.2e-11 43.3 7.4 0.0011 18.7 0.4 5.5 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.1 KKK14042.1 - 3.4e-07 30.7 10.6 0.0062 17.1 0.0 4.3 2 1 1 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 KKK14042.1 - 2.2e-06 27.0 8.1 0.056 13.2 0.1 5.5 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.12 KKK14042.1 - 0.0018 18.0 15.1 2.4 8.2 0.7 7.0 8 0 0 8 8 8 1 Tetratricopeptide repeat zf-C2H2_4 PF13894.1 KKK14042.1 - 0.003 17.7 0.1 0.003 17.7 0.0 3.6 4 0 0 4 4 2 1 C2H2-type zinc finger TPR_8 PF13181.1 KKK14042.1 - 0.015 15.0 4.8 0.17 11.7 0.4 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat zf-C2H2 PF00096.21 KKK14042.1 - 0.018 15.3 0.7 0.018 15.3 0.5 4.4 4 0 0 4 4 3 0 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 KKK14042.1 - 0.021 14.9 0.1 0.021 14.9 0.1 3.2 3 0 0 3 3 2 0 Zinc-finger double-stranded RNA-binding TPR_11 PF13414.1 KKK14042.1 - 0.025 14.2 9.4 3.2 7.4 0.2 4.6 2 2 1 5 5 5 0 TPR repeat zf-met PF12874.2 KKK14042.1 - 0.033 14.3 2.9 0.094 12.9 0.1 2.9 2 0 0 2 2 2 0 Zinc-finger of C2H2 type MIP-T3 PF10243.4 KKK14042.1 - 0.15 10.4 14.7 0.25 9.7 10.2 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 TPR_14 PF13428.1 KKK14042.1 - 0.36 11.5 14.2 9.9 7.1 0.0 6.1 4 2 3 7 7 6 0 Tetratricopeptide repeat TPR_1 PF00515.23 KKK14042.1 - 0.6 9.8 3.4 20 4.9 0.4 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat Menin PF05053.8 KKK14042.1 - 0.7 7.9 8.2 1.2 7.2 5.7 1.2 1 0 0 1 1 1 0 Menin zf-RING_3 PF14369.1 KKK14042.1 - 2.4 8.2 8.3 2.9 7.9 1.5 3.5 3 0 0 3 3 3 0 zinc-finger Mt_ATP-synt_D PF05873.7 KKK14044.1 - 7.8e-20 71.1 1.7 1e-19 70.7 1.2 1.0 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) Oxysterol_BP PF01237.13 KKK14044.1 - 0.003 16.0 1.7 0.0035 15.8 1.2 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein EzrA PF06160.7 KKK14044.1 - 0.033 12.3 4.4 0.04 12.1 2.4 1.5 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA BLOC1_2 PF10046.4 KKK14044.1 - 0.28 11.3 2.3 0.56 10.3 1.6 1.6 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 XhlA PF10779.4 KKK14044.1 - 0.44 10.4 2.8 0.88 9.5 1.9 1.6 1 1 0 1 1 1 0 Haemolysin XhlA DUF148 PF02520.12 KKK14044.1 - 0.82 9.4 6.6 0.2 11.4 2.3 1.6 2 1 0 2 2 2 0 Domain of unknown function DUF148 Spectrin PF00435.16 KKK14044.1 - 1.3 9.2 5.4 3 8.1 0.9 2.1 1 1 1 2 2 2 0 Spectrin repeat Tropomyosin_1 PF12718.2 KKK14044.1 - 6.7 6.5 8.8 15 5.4 2.3 2.4 1 1 0 2 2 2 0 Tropomyosin like Ribosomal_L14e PF01929.12 KKK14045.1 - 4.5e-25 87.7 0.3 7.2e-25 87.1 0.1 1.4 1 1 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.24 KKK14045.1 - 9.3e-08 31.5 1.0 1.8e-07 30.6 0.7 1.5 1 0 0 1 1 1 1 KOW motif NAC PF01849.13 KKK14046.1 - 4.7e-25 86.8 0.0 3.3e-23 80.9 0.0 2.2 2 0 0 2 2 2 1 NAC domain UBA PF00627.26 KKK14046.1 - 0.00078 19.2 0.1 0.0014 18.3 0.1 1.5 1 0 0 1 1 1 1 UBA/TS-N domain CDC45 PF02724.9 KKK14046.1 - 0.021 12.8 2.9 0.03 12.3 2.0 1.2 1 0 0 1 1 1 0 CDC45-like protein Zip PF02535.17 KKK14046.1 - 0.21 10.5 0.5 0.22 10.5 0.4 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter UreE_C PF05194.7 KKK14046.1 - 2 8.5 8.2 4.7 7.3 5.7 1.8 1 1 0 1 1 1 0 UreE urease accessory protein, C-terminal domain TRAP_alpha PF03896.11 KKK14046.1 - 3.7 6.4 5.9 6.4 5.6 4.1 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit SpoIIIAH PF12685.2 KKK14046.1 - 7.1 6.0 10.1 0.82 9.1 3.7 1.7 2 0 0 2 2 2 0 SpoIIIAH-like protein Thiolase_N PF00108.18 KKK14059.1 - 1.2e-78 263.7 0.1 2e-78 263.0 0.1 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 KKK14059.1 - 5.3e-44 148.5 1.9 1.2e-43 147.4 0.8 1.9 2 0 0 2 2 2 1 Thiolase, C-terminal domain Ribosomal_L50 PF10501.4 KKK14060.1 - 1.6e-24 86.0 0.2 2.6e-24 85.3 0.2 1.4 1 0 0 1 1 1 1 Ribosomal subunit 39S Rtf2 PF04641.7 KKK14061.1 - 8.3e-74 248.0 3.2 1.4e-73 247.3 2.2 1.3 1 0 0 1 1 1 1 Rtf2 RING-finger zf-RING_UBOX PF13445.1 KKK14061.1 - 1.1e-07 31.4 0.4 3e-07 30.0 0.3 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-Nse PF11789.3 KKK14061.1 - 1.4e-07 30.9 0.6 0.0063 16.0 0.1 2.4 2 0 0 2 2 2 2 Zinc-finger of the MIZ type in Nse subunit zf-RING_5 PF14634.1 KKK14061.1 - 0.00076 19.1 0.2 0.0019 17.8 0.1 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KKK14061.1 - 0.0039 16.8 0.1 0.0085 15.7 0.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KKK14061.1 - 0.023 14.5 0.1 0.085 12.6 0.1 1.9 1 1 1 2 2 2 0 Ring finger domain zf-C3HC4_2 PF13923.1 KKK14061.1 - 0.026 14.5 0.1 0.09 12.8 0.0 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Pol_alpha_B_N PF08418.5 KKK14061.1 - 0.24 10.8 8.8 0.43 10.0 6.1 1.4 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Macoilin PF09726.4 KKK14061.1 - 2.6 6.2 9.8 3.4 5.8 6.8 1.1 1 0 0 1 1 1 0 Transmembrane protein PRKCSH-like PF12999.2 KKK14062.1 - 3.8e-46 156.8 13.2 7.1e-28 97.3 1.0 3.2 3 0 0 3 3 3 2 Glucosidase II beta subunit-like Fib_alpha PF08702.5 KKK14062.1 - 0.00029 21.0 2.0 0.5 10.4 0.0 2.2 2 0 0 2 2 2 2 Fibrinogen alpha/beta chain family Prominin PF05478.6 KKK14062.1 - 0.23 8.9 0.3 0.29 8.6 0.2 1.1 1 0 0 1 1 1 0 Prominin CENP-F_leu_zip PF10473.4 KKK14062.1 - 0.33 10.7 15.9 0.57 10.0 10.6 1.7 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DivIC PF04977.10 KKK14062.1 - 0.57 9.7 12.6 2.1 7.9 0.6 2.4 2 1 0 2 2 2 0 Septum formation initiator GrpE PF01025.14 KKK14062.1 - 0.66 9.4 12.2 6.7 6.2 8.3 2.1 1 1 1 2 2 2 0 GrpE CASP_C PF08172.7 KKK14062.1 - 1.1 8.2 4.6 3.7 6.5 3.2 1.7 1 1 0 1 1 1 0 CASP C terminal IncA PF04156.9 KKK14062.1 - 1.5 8.3 10.6 3.3 7.2 7.3 1.5 1 1 0 1 1 1 0 IncA protein Ldl_recept_a PF00057.13 KKK14062.1 - 5 7.1 12.7 0.2 11.6 0.8 2.7 2 1 0 2 2 2 0 Low-density lipoprotein receptor domain class A DUF4200 PF13863.1 KKK14062.1 - 7 6.6 16.4 20 5.1 11.4 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) DAHP_synth_1 PF00793.15 KKK14063.1 - 3e-96 321.2 0.0 3.7e-96 320.9 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family adh_short PF00106.20 KKK14064.1 - 1.9e-09 37.6 0.1 1.6e-08 34.6 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KKK14064.1 - 8.5e-05 22.2 0.0 0.00014 21.5 0.0 1.4 1 0 0 1 1 1 1 KR domain DUF2458 PF10454.4 KKK14065.1 - 6e-50 169.0 0.0 7.6e-50 168.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2458) CAF-1_p150 PF11600.3 KKK14065.1 - 0.022 14.1 4.3 0.033 13.5 2.8 1.4 1 1 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Sec66 PF09802.4 KKK14065.1 - 0.041 13.2 0.4 0.072 12.4 0.3 1.3 1 0 0 1 1 1 0 Preprotein translocase subunit Sec66 COX14 PF14880.1 KKK14066.1 - 6.3e-20 70.5 0.6 6.3e-20 70.5 0.4 1.7 2 0 0 2 2 2 1 Cytochrome oxidase c assembly DUF605 PF04652.11 KKK14066.1 - 0.002 17.5 1.1 0.002 17.5 0.7 1.9 2 0 0 2 2 2 1 Vta1 like Fungal_trans_2 PF11951.3 KKK14074.1 - 9.7e-15 54.0 1.6 1.8e-14 53.1 1.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain WW PF00397.21 KKK14075.1 - 4.1e-09 36.1 0.6 9.2e-09 35.0 0.4 1.7 1 0 0 1 1 1 1 WW domain UNC45-central PF11701.3 KKK14105.1 - 9.6e-29 100.0 2.3 6.6e-24 84.3 0.1 3.6 3 1 1 4 4 4 2 Myosin-binding striated muscle assembly central Arm PF00514.18 KKK14105.1 - 1.6e-06 27.7 14.8 4.8 7.1 0.0 8.0 8 0 0 8 8 8 3 Armadillo/beta-catenin-like repeat TPR_15 PF13429.1 KKK14105.1 - 0.0013 17.8 0.9 0.0048 16.0 0.1 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat HEAT_2 PF13646.1 KKK14105.1 - 0.0021 18.2 10.5 0.0034 17.6 1.6 4.8 4 1 1 5 5 5 1 HEAT repeats TPR_11 PF13414.1 KKK14105.1 - 0.0095 15.5 0.3 0.021 14.4 0.2 1.6 1 0 0 1 1 1 1 TPR repeat TPR_14 PF13428.1 KKK14105.1 - 0.098 13.3 0.3 0.098 13.3 0.2 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat HEAT_EZ PF13513.1 KKK14105.1 - 0.19 12.2 15.3 19 5.8 0.4 5.9 5 0 0 5 5 5 0 HEAT-like repeat HEAT PF02985.17 KKK14105.1 - 4.6 7.5 5.8 8.3 6.7 0.1 4.2 4 0 0 4 4 4 0 HEAT repeat PRMT5 PF05185.11 KKK14106.1 - 1.8e-157 524.8 0.0 2.5e-157 524.3 0.0 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Tfb4 PF03850.9 KKK14107.1 - 3.2e-117 390.6 0.0 3.8e-117 390.4 0.0 1.0 1 0 0 1 1 1 1 Transcription factor Tfb4 CAP_N PF01213.14 KKK14107.1 - 0.38 9.9 3.2 0.68 9.1 2.2 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal GDPD PF03009.12 KKK14108.1 - 8.6e-68 228.5 0.0 9.8e-67 225.1 0.0 2.4 3 0 0 3 3 3 1 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.2 KKK14108.1 - 5.7e-29 100.3 0.3 1.4e-12 47.7 0.1 4.2 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) SPX PF03105.14 KKK14108.1 - 2.8e-28 99.5 5.1 1.2e-14 54.7 0.4 3.4 1 1 1 2 2 2 2 SPX domain Ank_4 PF13637.1 KKK14108.1 - 1.5e-27 95.4 2.5 8.9e-10 38.8 0.0 5.1 6 0 0 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.25 KKK14108.1 - 2.4e-23 80.7 5.8 0.00038 20.1 0.0 7.0 7 0 0 7 7 7 4 Ankyrin repeat Ank_5 PF13857.1 KKK14108.1 - 1.4e-19 69.6 1.6 2.1e-07 30.9 0.1 5.2 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 KKK14108.1 - 4.4e-15 54.2 2.8 0.028 14.6 0.0 6.5 7 0 0 7 7 7 3 Ankyrin repeat OB_NTP_bind PF07717.11 KKK14109.1 - 2.2e-27 95.1 0.1 5.7e-27 93.8 0.0 1.7 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 KKK14109.1 - 7.5e-25 86.9 0.0 2e-24 85.5 0.0 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 KKK14109.1 - 6.8e-11 41.8 0.0 1.7e-10 40.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KKK14109.1 - 3.8e-07 29.7 0.8 7.4e-07 28.8 0.3 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KKK14109.1 - 1e-05 25.6 0.1 3.7e-05 23.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.17 KKK14109.1 - 0.00025 20.5 0.3 0.00079 18.9 0.2 1.8 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain ResIII PF04851.10 KKK14109.1 - 0.0024 17.7 0.0 0.9 9.3 0.0 2.3 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.9 KKK14109.1 - 0.004 16.9 1.6 0.0043 16.8 0.2 1.7 2 0 0 2 2 2 1 Flavivirus DEAD domain T2SE PF00437.15 KKK14109.1 - 0.0056 15.6 0.0 0.011 14.6 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_30 PF13604.1 KKK14109.1 - 0.1 12.1 0.0 0.22 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 KKK14109.1 - 0.17 11.4 0.0 0.49 9.9 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Smr PF01713.16 KKK14110.1 - 7.3e-05 22.8 0.8 0.0005 20.2 0.0 2.4 2 1 1 3 3 3 1 Smr domain YscJ_FliF_C PF08345.6 KKK14110.1 - 0.016 15.1 6.6 0.026 14.5 4.6 1.3 1 0 0 1 1 1 0 Flagellar M-ring protein C-terminal FAM60A PF15396.1 KKK14110.1 - 0.034 13.8 1.2 0.035 13.8 0.8 1.1 1 0 0 1 1 1 0 Protein Family FAM60A FlaG PF03646.10 KKK14110.1 - 0.13 12.4 9.6 1.4 9.0 6.4 2.0 2 0 0 2 2 2 0 FlaG protein DUF2422 PF10337.4 KKK14110.1 - 0.13 11.0 0.1 0.15 10.8 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) DUF2201_N PF13203.1 KKK14110.1 - 0.14 11.2 5.1 0.15 11.2 3.6 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain Pex14_N PF04695.8 KKK14110.1 - 0.21 11.6 8.7 0.29 11.1 6.0 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Suf PF05843.9 KKK14110.1 - 0.25 11.0 5.5 0.27 10.9 3.8 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) PAT1 PF09770.4 KKK14110.1 - 0.66 8.1 18.3 0.69 8.0 12.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Med15 PF09606.5 KKK14110.1 - 1.5 6.9 28.0 1.5 6.8 19.4 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DivIC PF04977.10 KKK14110.1 - 2 7.9 7.9 3.6 7.1 5.5 1.4 1 0 0 1 1 1 0 Septum formation initiator SapB_1 PF05184.10 KKK14110.1 - 2.2 8.2 5.3 2.2 8.2 0.7 2.6 3 0 0 3 3 3 0 Saposin-like type B, region 1 DUF4175 PF13779.1 KKK14110.1 - 3.3 5.2 21.2 4 5.0 14.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) ATAD4 PF15321.1 KKK14110.1 - 4.6 8.3 6.1 2.7 9.0 2.6 1.8 2 0 0 2 2 2 0 ATPase family AAA domain containing 4 BAF1_ABF1 PF04684.8 KKK14110.1 - 6.1 5.5 20.9 7.2 5.3 14.5 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor CDC14 PF08045.6 KKK14111.1 - 4.5e-101 337.2 0.0 5.2e-101 337.1 0.0 1.0 1 0 0 1 1 1 1 Cell division control protein 14, SIN component polyprenyl_synt PF00348.12 KKK14112.1 - 2.2e-58 197.1 0.0 2.9e-58 196.7 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Tom37_C PF11801.3 KKK14113.1 - 7.9e-06 25.8 0.4 0.0007 19.5 0.3 2.1 1 1 1 2 2 2 2 Tom37 C-terminal domain GST_C_2 PF13410.1 KKK14113.1 - 0.00011 22.0 0.2 0.00024 20.9 0.2 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF717 PF05338.7 KKK14113.1 - 0.056 13.3 0.0 0.3 11.0 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF717) Sugar_tr PF00083.19 KKK14114.1 - 8.1e-105 350.9 29.2 9.3e-105 350.7 20.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KKK14114.1 - 1.3e-22 80.0 34.5 3.2e-16 59.0 8.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KKK14114.1 - 0.003 16.0 3.6 0.003 16.0 2.5 3.3 1 1 1 3 3 3 2 MFS/sugar transport protein YccV-like PF08755.6 KKK14115.1 - 1.1e-22 79.8 0.0 3.8e-22 78.1 0.0 1.9 2 1 0 2 2 2 1 Hemimethylated DNA-binding protein YccV like Transglut_core2 PF13369.1 KKK14115.1 - 1.7e-09 37.3 0.0 4.1e-09 36.1 0.0 1.6 2 0 0 2 2 2 1 Transglutaminase-like superfamily DnaJ PF00226.26 KKK14116.1 - 2.3e-25 88.1 1.7 6e-25 86.7 1.2 1.8 1 0 0 1 1 1 1 DnaJ domain zf-C2H2_jaz PF12171.3 KKK14116.1 - 5.9e-11 42.1 13.5 8.5e-10 38.4 3.5 3.0 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KKK14116.1 - 1.3e-10 41.0 9.6 2.3e-08 33.9 1.8 2.6 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 KKK14116.1 - 6.4e-06 26.2 9.2 0.00071 19.6 1.1 2.8 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.1 KKK14116.1 - 9.4e-05 22.4 8.5 0.048 14.0 0.8 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KKK14116.1 - 0.00027 21.1 12.5 0.044 14.1 0.6 3.1 3 0 0 3 3 2 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 KKK14116.1 - 0.0023 17.7 10.2 0.32 10.9 0.5 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger LIM PF00412.17 KKK14116.1 - 0.028 14.4 3.3 0.25 11.4 0.3 2.4 2 0 0 2 2 2 0 LIM domain zf-H2C2_2 PF13465.1 KKK14116.1 - 0.15 12.3 7.5 0.5 10.7 0.1 3.3 3 0 0 3 3 3 0 Zinc-finger double domain CpXC PF14353.1 KKK14116.1 - 0.35 10.8 6.8 4.8 7.1 0.0 3.2 3 0 0 3 3 3 0 CpXC protein C1_4 PF07975.7 KKK14116.1 - 0.39 10.7 3.5 8.6 6.4 0.1 2.5 2 0 0 2 2 2 0 TFIIH C1-like domain zf-LYAR PF08790.6 KKK14116.1 - 1.7 8.4 5.0 0.6 9.8 0.5 2.4 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zinc_ribbon_4 PF13717.1 KKK14116.1 - 2.3 7.9 5.7 0.54 9.9 0.3 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 KKK14116.1 - 3.3 7.3 5.6 0.9 9.1 0.3 2.2 2 0 0 2 2 2 0 zinc-ribbon domain R3H PF01424.17 KKK14117.1 - 2.5e-12 46.2 0.2 6.8e-12 44.9 0.0 1.9 2 0 0 2 2 2 1 R3H domain G-patch PF01585.18 KKK14117.1 - 3.1e-10 39.6 0.2 7.9e-10 38.3 0.1 1.8 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 KKK14117.1 - 2.1e-05 24.2 0.1 6.9e-05 22.6 0.1 1.9 1 0 0 1 1 1 1 DExH-box splicing factor binding site VCX_VCY PF15231.1 KKK14117.1 - 0.014 15.8 1.0 0.037 14.4 0.7 1.7 1 0 0 1 1 1 0 Variable charge X/Y family Phosphoesterase PF04185.9 KKK14119.1 - 2.6e-56 191.4 5.5 1.5e-55 188.9 3.8 2.0 1 1 0 1 1 1 1 Phosphoesterase family VIT1 PF01988.14 KKK14120.1 - 8.6e-45 152.8 5.1 3.7e-44 150.7 3.5 1.8 1 1 0 1 1 1 1 VIT family PDGLE PF13190.1 KKK14120.1 - 0.011 15.4 0.1 0.039 13.6 0.1 2.1 1 1 0 1 1 1 0 PDGLE domain Peptidase_M19 PF01244.16 KKK14121.1 - 3e-102 341.8 0.0 3.5e-102 341.6 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) MFS_1 PF07690.11 KKK14122.1 - 4.3e-46 157.2 50.6 2.2e-43 148.3 33.7 2.9 2 1 0 2 2 2 2 Major Facilitator Superfamily Zn_clus PF00172.13 KKK14123.1 - 2.6e-08 33.6 7.3 2.6e-08 33.6 5.0 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FF PF01846.14 KKK14126.1 - 1.9e-59 197.3 17.0 3.9e-15 55.5 0.3 7.2 6 1 0 6 6 6 6 FF domain WW PF00397.21 KKK14126.1 - 2.3e-18 65.7 9.0 1.1e-08 34.8 2.7 2.7 2 0 0 2 2 2 2 WW domain DUF3808 PF10300.4 KKK14127.1 - 1.3e-156 521.8 0.3 2.1e-156 521.1 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) DehI PF10778.4 KKK14127.1 - 0.017 14.6 0.0 0.052 13.0 0.0 1.8 1 1 0 1 1 1 0 Halocarboxylic acid dehydrogenase DehI PGK PF00162.14 KKK14128.1 - 6.1e-138 459.5 3.9 3.7e-136 453.6 2.7 2.0 1 1 0 1 1 1 1 Phosphoglycerate kinase SBP_bac_8 PF13416.1 KKK14128.1 - 0.015 15.0 1.3 0.029 14.0 0.5 1.7 2 0 0 2 2 2 0 Bacterial extracellular solute-binding protein Trs65 PF12735.2 KKK14129.1 - 1.1e-91 307.4 0.0 1.4e-91 307.0 0.0 1.2 1 0 0 1 1 1 1 TRAPP trafficking subunit Trs65 Mpv17_PMP22 PF04117.7 KKK14129.1 - 5.4e-22 77.2 0.1 1.3e-21 76.0 0.1 1.7 1 0 0 1 1 1 1 Mpv17 / PMP22 family Peptidase_M22 PF00814.20 KKK14173.1 - 2.5e-84 282.9 0.0 2.9e-84 282.7 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family BRE1 PF08647.6 KKK14174.1 - 5.5e-30 103.2 11.6 5.5e-30 103.2 8.0 6.9 5 3 2 7 7 6 1 BRE1 E3 ubiquitin ligase zf-C3HC4_2 PF13923.1 KKK14174.1 - 3.6e-09 36.4 10.0 6.2e-09 35.7 6.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KKK14174.1 - 1.2e-08 34.4 8.0 2.1e-08 33.7 5.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KKK14174.1 - 5.8e-08 32.2 10.2 1.1e-07 31.4 7.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KKK14174.1 - 6.8e-07 29.0 7.8 1.2e-06 28.2 5.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 KKK14174.1 - 6.9e-06 25.7 10.7 1.2e-05 24.9 7.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 KKK14174.1 - 2.9e-05 23.6 5.8 9.3e-05 22.0 4.0 2.0 1 0 0 1 1 1 1 RING-type zinc-finger TPR_MLP1_2 PF07926.7 KKK14174.1 - 0.0015 18.2 11.2 0.0015 18.2 7.8 6.3 2 2 3 6 6 6 2 TPR/MLP1/MLP2-like protein zf-rbx1 PF12678.2 KKK14174.1 - 0.0049 16.9 4.4 0.013 15.6 2.2 2.3 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4_4 PF15227.1 KKK14174.1 - 0.0073 16.1 6.6 0.014 15.2 4.6 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 KKK14174.1 - 0.014 14.9 7.2 0.071 12.7 5.3 1.9 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain DUF1272 PF06906.6 KKK14174.1 - 0.02 14.7 6.2 0.041 13.7 4.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) Prok-RING_4 PF14447.1 KKK14174.1 - 0.03 13.8 3.4 0.059 12.9 2.3 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_6 PF14835.1 KKK14174.1 - 0.25 11.1 3.6 0.49 10.2 2.5 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein PLAC9 PF15205.1 KKK14174.1 - 0.35 11.1 1.9 4.4 7.6 0.0 3.8 5 0 0 5 5 3 0 Placenta-specific protein 9 zf-Nse PF11789.3 KKK14174.1 - 0.46 10.0 5.8 1.1 8.7 4.0 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C2HC_2 PF13913.1 KKK14174.1 - 0.54 9.9 6.5 1 9.0 1.8 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type FYVE PF01363.16 KKK14174.1 - 0.98 9.3 11.7 12 5.8 8.1 2.5 1 1 1 2 2 2 0 FYVE zinc finger Reo_sigmaC PF04582.7 KKK14174.1 - 1.1 8.3 37.0 0.068 12.3 2.0 5.2 2 1 3 5 5 5 0 Reovirus sigma C capsid protein IncA PF04156.9 KKK14174.1 - 2.2 7.8 70.2 0.018 14.6 8.3 5.4 1 1 4 5 5 5 0 IncA protein zf-FCS PF06467.9 KKK14174.1 - 5.3 6.7 8.7 9.4 5.9 0.1 2.5 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif Myb_DNA-binding PF00249.26 KKK14175.1 - 2.5e-05 24.2 0.0 4.7e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF1183 PF06682.7 KKK14176.1 - 5.3e-62 210.2 0.0 7.8e-62 209.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1183) PRA1 PF03208.14 KKK14176.1 - 0.25 10.6 2.6 0.43 9.9 1.8 1.5 1 1 0 1 1 1 0 PRA1 family protein GIDA PF01134.17 KKK14177.1 - 8.7e-154 512.1 0.0 1.1e-153 511.8 0.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc_3 PF13932.1 KKK14177.1 - 6e-20 71.0 0.1 1.8e-19 69.5 0.1 1.8 1 0 0 1 1 1 1 GidA associated domain 3 Pyr_redox_2 PF07992.9 KKK14177.1 - 4.5e-07 29.9 0.5 9.3e-07 28.9 0.4 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KKK14177.1 - 3.6e-06 26.3 1.1 6.4e-06 25.5 0.8 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.19 KKK14177.1 - 3.1e-05 23.0 2.0 0.061 12.2 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.16 KKK14177.1 - 0.0011 18.5 0.2 0.0023 17.5 0.1 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.19 KKK14177.1 - 0.0016 17.3 1.6 0.0016 17.3 1.1 1.9 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 KKK14177.1 - 0.05 12.0 2.4 0.13 10.6 0.3 2.2 3 0 0 3 3 3 0 HI0933-like protein Gti1_Pac2 PF09729.4 KKK14178.1 - 2.6e-63 212.8 0.0 6.3e-63 211.6 0.0 1.6 2 0 0 2 2 2 1 Gti1/Pac2 family ABC1 PF03109.11 KKK14180.1 - 3.8e-34 117.2 0.0 1e-32 112.6 0.0 2.6 2 0 0 2 2 2 1 ABC1 family UreF PF01730.11 KKK14181.1 - 1.3e-14 54.5 0.1 2e-14 53.9 0.1 1.3 1 0 0 1 1 1 1 UreF EPL1 PF10513.4 KKK14182.1 - 2.7e-31 108.9 0.7 2.7e-31 108.9 0.5 3.3 2 1 1 3 3 3 1 Enhancer of polycomb-like EF-hand_1 PF00036.27 KKK14183.1 - 1.4e-25 86.5 19.0 1e-07 30.7 0.5 4.5 5 0 0 5 5 5 4 EF hand EF-hand_7 PF13499.1 KKK14183.1 - 1.1e-22 79.9 4.5 8e-12 45.1 0.7 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 KKK14183.1 - 9e-21 71.8 7.7 8.4e-06 25.2 0.0 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 KKK14183.1 - 4.3e-18 63.7 14.1 9.8e-06 24.6 0.2 4.5 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.1 KKK14183.1 - 2.7e-15 55.7 16.5 2.4e-05 23.8 0.6 4.4 2 2 2 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.4 KKK14183.1 - 3.5e-07 30.2 0.0 0.00088 19.2 0.0 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 KKK14183.1 - 0.00049 19.7 11.2 0.44 10.3 0.3 4.1 1 1 3 4 4 4 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 KKK14183.1 - 0.014 15.3 0.1 0.75 9.7 0.0 2.9 2 1 1 3 3 3 0 EF-hand domain Anthrax-tox_M PF09156.5 KKK14183.1 - 0.023 13.8 1.0 0.057 12.5 0.0 1.8 2 0 0 2 2 2 0 Anthrax toxin lethal factor, middle domain ATP-cone PF03477.11 KKK14183.1 - 0.1 13.0 0.3 0.24 11.8 0.2 1.5 1 0 0 1 1 1 0 ATP cone domain Ribosomal_S9 PF00380.14 KKK14185.1 - 3.3e-37 127.4 0.2 5.2e-37 126.7 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Mannosyl_trans3 PF11051.3 KKK14186.1 - 7.4e-79 264.8 0.0 1.9e-78 263.5 0.0 1.6 1 1 0 1 1 1 1 Mannosyltransferase putative SET PF00856.23 KKK14187.1 - 7.5e-17 62.1 0.0 3.9e-15 56.5 0.0 2.7 2 1 0 2 2 2 1 SET domain Rubis-subs-bind PF09273.6 KKK14187.1 - 1e-05 25.4 4.0 4.2e-05 23.4 2.8 2.0 1 1 0 1 1 1 1 Rubisco LSMT substrate-binding LEM PF03020.10 KKK14187.1 - 0.00061 19.1 0.1 0.0023 17.3 0.1 1.9 1 0 0 1 1 1 1 LEM domain EF1G PF00647.14 KKK14188.1 - 1.8e-43 146.6 0.1 3.3e-43 145.7 0.1 1.4 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.20 KKK14188.1 - 8.4e-13 48.1 0.0 1.9e-12 46.9 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KKK14188.1 - 7.9e-10 38.4 0.1 7.2e-09 35.4 0.0 2.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 KKK14188.1 - 7e-09 35.7 0.1 2.7e-08 33.8 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 KKK14188.1 - 6.4e-06 26.5 0.0 1.4e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 KKK14188.1 - 0.00083 19.5 0.0 0.0017 18.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KKK14188.1 - 0.077 13.0 0.0 0.29 11.1 0.0 2.0 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain DUF2404 PF10296.4 KKK14189.1 - 4.4e-05 23.5 0.0 7.3e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) ARD PF03079.9 KKK14190.1 - 1.9e-45 154.6 0.3 2.2e-45 154.3 0.2 1.0 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.6 KKK14190.1 - 4.1e-10 39.0 0.0 7.1e-10 38.2 0.0 1.4 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.14 KKK14190.1 - 4.9e-07 29.5 0.0 7.2e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.17 KKK14190.1 - 0.0019 17.6 0.0 0.0028 17.1 0.0 1.2 1 0 0 1 1 1 1 Cupin Gln-synt_N PF03951.14 KKK14205.1 - 6.3e-11 41.7 0.0 7.1e-11 41.5 0.0 1.0 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain WD40 PF00400.27 KKK14245.1 - 6e-22 76.6 16.3 3.7e-08 32.9 0.0 6.4 7 0 0 7 7 7 4 WD domain, G-beta repeat Sad1_UNC PF07738.8 KKK14261.1 - 2.7e-33 114.6 0.0 5e-33 113.7 0.0 1.4 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal DUF1451 PF07295.6 KKK14261.1 - 0.083 12.6 3.2 0.1 12.3 1.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1451) Pkinase PF00069.20 KKK14262.1 - 4.3e-58 196.5 0.0 6.9e-58 195.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK14262.1 - 2.4e-31 108.7 0.0 3.3e-31 108.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KKK14262.1 - 4.8e-10 38.8 0.0 2e-07 30.2 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.9 KKK14262.1 - 0.099 11.6 0.0 0.17 10.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family MMR_HSR1 PF01926.18 KKK14263.1 - 7e-17 61.4 0.1 2.6e-14 53.1 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 KKK14263.1 - 1.6e-07 30.7 0.1 4.8e-05 22.6 0.0 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B DUF258 PF03193.11 KKK14263.1 - 0.0004 19.6 0.0 0.00077 18.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 KKK14263.1 - 0.00051 19.9 4.7 0.099 12.4 0.2 3.5 3 1 0 3 3 3 2 Dynamin family AIG1 PF04548.11 KKK14263.1 - 0.0074 15.4 0.0 0.015 14.3 0.0 1.5 1 0 0 1 1 1 1 AIG1 family Miro PF08477.8 KKK14263.1 - 0.034 14.6 0.3 0.19 12.2 0.0 2.4 2 0 0 2 2 2 0 Miro-like protein Acyl-CoA_dh_1 PF00441.19 KKK14264.1 - 1.9e-27 96.1 1.3 3.2e-27 95.4 0.9 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 KKK14264.1 - 3.6e-16 58.3 0.0 8.1e-16 57.2 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Spo12 PF05032.7 KKK14264.1 - 5.7e-16 57.8 2.8 1.2e-15 56.7 1.9 1.6 1 0 0 1 1 1 1 Spo12 family Acyl-CoA_dh_2 PF08028.6 KKK14264.1 - 2.8e-13 50.2 2.7 4.7e-13 49.5 1.9 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 KKK14264.1 - 5.5e-12 46.2 0.0 1.2e-11 45.1 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Pol_alpha_B_N PF08418.5 KKK14264.1 - 0.058 12.9 2.5 0.097 12.1 1.7 1.3 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal FAM110_C PF14160.1 KKK14264.1 - 0.074 14.0 0.9 0.14 13.0 0.6 1.4 1 0 0 1 1 1 0 Centrosome-associated C terminus LTV PF04180.9 KKK14265.1 - 1.4e-73 248.8 7.0 4.5e-73 247.1 4.8 1.8 1 1 0 1 1 1 1 Low temperature viability protein DGF-1_C PF11040.3 KKK14265.1 - 1 9.2 6.5 0.39 10.6 0.7 3.1 3 1 0 3 3 3 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus YL1 PF05764.8 KKK14265.1 - 1.1 8.7 7.0 0.17 11.4 1.6 2.0 2 1 0 2 2 2 0 YL1 nuclear protein Pep3_Vps18 PF05131.9 KKK14266.1 - 6.5e-48 161.8 0.0 1.7e-47 160.5 0.0 1.8 1 0 0 1 1 1 1 Pep3/Vps18/deep orange family Clathrin PF00637.15 KKK14266.1 - 9.6e-11 41.4 3.8 7.2e-05 22.4 0.0 3.7 3 0 0 3 3 3 2 Region in Clathrin and VPS zf-RING_2 PF13639.1 KKK14266.1 - 0.0026 17.5 0.4 0.0066 16.2 0.3 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 KKK14266.1 - 0.0051 16.5 0.3 0.013 15.2 0.2 1.7 1 0 0 1 1 1 1 zinc-RING finger domain DUF2175 PF09943.4 KKK14266.1 - 0.018 15.0 0.5 1.3 9.0 0.0 2.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) DUF1664 PF07889.7 KKK14266.1 - 0.025 14.3 1.4 0.46 10.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Vps39_2 PF10367.4 KKK14266.1 - 0.03 14.5 0.0 0.07 13.3 0.0 1.7 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 DUF3849 PF12960.2 KKK14266.1 - 0.051 13.5 0.1 0.11 12.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3849) zf-C3HC4 PF00097.20 KKK14266.1 - 0.18 11.5 0.2 0.54 9.9 0.1 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) UCH_1 PF13423.1 KKK14267.1 - 4.3e-73 246.3 0.0 9.8e-73 245.1 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH PF00443.24 KKK14267.1 - 3.1e-14 52.7 0.0 5.9e-14 51.8 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase EnY2 PF10163.4 KKK14267.1 - 0.088 12.7 0.1 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 Transcription factor e(y)2 Ribosomal_L5_C PF00673.16 KKK14268.1 - 7.7e-27 92.8 0.0 1.8e-26 91.6 0.0 1.6 2 0 0 2 2 2 1 ribosomal L5P family C-terminus Septin PF00735.13 KKK14278.1 - 3.3e-10 39.4 0.0 5e-09 35.5 0.0 2.1 1 1 0 1 1 1 1 Septin AAA_33 PF13671.1 KKK14278.1 - 0.0054 16.6 0.0 0.018 14.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain ATP_bind_1 PF03029.12 KKK14278.1 - 0.0078 15.7 0.0 0.014 14.9 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_25 PF13481.1 KKK14278.1 - 0.016 14.6 0.0 0.063 12.6 0.0 1.9 1 1 0 1 1 1 0 AAA domain MobB PF03205.9 KKK14278.1 - 0.03 14.0 0.0 0.057 13.1 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.1 KKK14278.1 - 0.036 14.8 0.0 0.085 13.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 KKK14278.1 - 0.043 13.3 0.4 0.14 11.7 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA PF00004.24 KKK14278.1 - 0.06 13.5 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KKK14278.1 - 0.062 13.2 0.3 0.25 11.3 0.0 2.1 2 1 0 2 2 2 0 AAA ATPase domain Mg_chelatase PF01078.16 KKK14278.1 - 0.065 12.3 0.0 0.16 11.1 0.0 1.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI T2SE PF00437.15 KKK14278.1 - 0.07 12.0 0.0 0.16 10.8 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein Zeta_toxin PF06414.7 KKK14278.1 - 0.096 11.7 0.0 0.24 10.4 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_23 PF13476.1 KKK14278.1 - 0.14 12.4 0.1 0.31 11.3 0.1 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 KKK14278.1 - 0.15 12.3 0.0 0.55 10.5 0.0 1.9 2 0 0 2 2 2 0 ABC transporter MMR_HSR1 PF01926.18 KKK14278.1 - 0.19 11.7 0.0 0.9 9.5 0.0 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_24 PF13479.1 KKK14278.1 - 0.2 11.1 0.0 0.36 10.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain HSP90 PF00183.13 KKK14279.1 - 2.1e-254 844.8 36.4 2.4e-254 844.6 25.3 1.0 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.21 KKK14279.1 - 1e-10 41.2 0.0 1.9e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 KKK14279.1 - 1.5e-10 40.8 0.1 1.5e-10 40.8 0.1 2.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF1676 PF07898.8 KKK14279.1 - 0.064 13.5 0.4 0.064 13.5 0.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1676) LOH1CR12 PF10158.4 KKK14279.1 - 0.14 11.9 3.0 0.14 11.9 0.1 2.4 3 0 0 3 3 3 0 Tumour suppressor protein NTF2 PF02136.15 KKK14280.1 - 2.5e-26 92.3 0.5 4.5e-26 91.5 0.4 1.4 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.17 KKK14280.1 - 3.3e-09 36.2 0.1 5.8e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KKK14280.1 - 1.4e-06 28.0 0.0 2.8e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KKK14280.1 - 5.5e-06 26.2 0.0 9.5e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Imm16 PF15565.1 KKK14280.1 - 0.026 14.3 0.4 0.15 11.9 0.1 2.1 2 0 0 2 2 2 0 Immunity protein 16 RRM_3 PF08777.6 KKK14280.1 - 0.046 13.5 0.5 0.19 11.5 0.0 2.1 2 0 0 2 2 2 0 RNA binding motif Response_reg PF00072.19 KKK14292.1 - 5.4e-20 71.4 0.0 7.5e-13 48.4 0.0 2.3 2 0 0 2 2 2 2 Response regulator receiver domain SH3_1 PF00018.23 KKK14293.1 - 4.3e-10 38.8 0.1 8.6e-10 37.8 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KKK14293.1 - 8.1e-07 28.4 0.0 1.8e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 KKK14293.1 - 1.3e-05 24.7 0.0 2.3e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain DUF2069 PF09842.4 KKK14293.1 - 0.058 13.3 2.8 0.9 9.5 0.8 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2069) Herpes_LMP1 PF05297.6 KKK14293.1 - 0.15 11.0 8.5 0.088 11.7 1.1 2.3 2 1 0 2 2 2 0 Herpesvirus latent membrane protein 1 (LMP1) PQ-loop PF04193.9 KKK14294.1 - 5.3e-19 67.5 0.6 5.3e-19 67.5 0.4 3.3 3 1 0 3 3 3 1 PQ loop repeat Vpu PF00558.14 KKK14294.1 - 0.079 12.5 3.3 0.18 11.3 0.2 2.3 2 0 0 2 2 2 0 Vpu protein UL2 PF08196.6 KKK14294.1 - 0.32 10.7 1.7 18 5.1 1.2 2.7 1 1 0 1 1 1 0 UL2 protein CUB_2 PF02408.15 KKK14297.1 - 0.049 13.1 0.1 0.091 12.3 0.0 1.3 1 0 0 1 1 1 0 CUB-like domain DUF2235 PF09994.4 KKK14298.1 - 6.6e-68 229.0 0.0 9.5e-68 228.5 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Abhydrolase_5 PF12695.2 KKK14298.1 - 0.042 13.6 0.0 0.081 12.6 0.0 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family MMR_HSR1 PF01926.18 KKK14299.1 - 9.6e-07 28.7 0.1 5.9e-06 26.2 0.0 2.5 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_23 PF13476.1 KKK14299.1 - 1.9e-06 28.3 3.2 0.0039 17.5 0.0 2.8 3 0 0 3 3 3 2 AAA domain DUF258 PF03193.11 KKK14299.1 - 3.4e-06 26.3 0.0 9.1e-06 24.9 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 KKK14299.1 - 0.00035 19.7 0.0 0.54 9.3 0.0 2.7 2 0 0 2 2 2 2 AIG1 family AAA_29 PF13555.1 KKK14299.1 - 0.00063 19.2 0.0 0.0015 17.9 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.1 KKK14299.1 - 0.00085 19.3 0.0 0.01 15.8 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain FtsK_SpoIIIE PF01580.13 KKK14299.1 - 0.0017 17.8 0.0 0.0041 16.6 0.0 1.6 1 0 0 1 1 1 1 FtsK/SpoIIIE family T2SE PF00437.15 KKK14299.1 - 0.0031 16.4 0.0 0.0066 15.3 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein Dynamin_N PF00350.18 KKK14299.1 - 0.018 14.8 4.5 3.1 7.6 0.0 3.7 3 0 0 3 3 3 0 Dynamin family GTP_EFTU PF00009.22 KKK14299.1 - 0.02 14.3 0.0 0.071 12.5 0.0 2.0 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain ABC_tran PF00005.22 KKK14299.1 - 0.045 14.0 2.6 0.38 11.0 0.0 3.1 3 0 0 3 3 3 0 ABC transporter AAA_25 PF13481.1 KKK14299.1 - 0.061 12.7 0.0 4.1 6.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 KKK14299.1 - 0.083 12.3 1.2 0.13 11.7 0.1 1.8 2 0 0 2 2 2 0 AAA-like domain RNA_helicase PF00910.17 KKK14299.1 - 0.11 12.7 0.1 0.72 10.0 0.0 2.4 2 0 0 2 2 2 0 RNA helicase AAA_17 PF13207.1 KKK14299.1 - 0.12 13.2 1.1 1.6 9.5 0.0 3.4 5 0 0 5 5 3 0 AAA domain Snf7 PF03357.16 KKK14299.1 - 0.15 11.4 9.6 0.01 15.1 2.6 2.1 2 0 0 2 2 2 0 Snf7 DUF87 PF01935.12 KKK14299.1 - 0.15 11.8 0.0 0.15 11.8 0.0 3.7 4 1 0 4 4 3 0 Domain of unknown function DUF87 DUF948 PF06103.6 KKK14299.1 - 0.42 10.5 3.8 0.54 10.1 0.3 3.0 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) COG2 PF06148.6 KKK14299.1 - 4.5 7.1 13.6 6.3 6.6 0.2 4.4 4 0 0 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 Sugar_tr PF00083.19 KKK14300.1 - 2.8e-81 273.3 27.3 3.2e-81 273.1 18.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KKK14300.1 - 8.4e-39 133.2 53.1 3.5e-36 124.6 20.9 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KKK14300.1 - 1e-05 23.9 7.7 2.4e-05 22.7 3.1 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.2 KKK14300.1 - 0.041 13.6 1.8 0.088 12.6 0.0 2.5 3 0 0 3 3 3 0 MFS_1 like family MFS_3 PF05977.8 KKK14300.1 - 1.8 6.6 14.1 0.013 13.6 1.8 2.8 3 1 1 4 4 4 0 Transmembrane secretion effector Fungal_trans PF04082.13 KKK14301.1 - 3.8e-09 35.7 0.0 9.7e-09 34.4 0.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 KKK14301.1 - 4.1e-08 33.1 14.9 0.0012 19.1 1.4 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KKK14301.1 - 1.4e-06 28.2 18.4 1.7e-06 27.9 3.5 3.6 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 KKK14301.1 - 2.5e-06 27.3 11.9 0.012 15.9 2.7 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2HC_2 PF13913.1 KKK14301.1 - 0.0043 16.6 0.2 0.0043 16.6 0.2 2.2 2 0 0 2 2 2 1 zinc-finger of a C2HC-type FAD_binding_3 PF01494.14 KKK14302.1 - 6.4e-73 245.8 0.0 9.4e-73 245.2 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 KKK14302.1 - 0.00089 18.4 0.0 0.0021 17.1 0.0 1.5 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 KKK14302.1 - 0.002 18.0 0.0 0.016 15.0 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KKK14302.1 - 0.0025 17.7 0.0 0.0061 16.5 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KKK14302.1 - 0.004 16.0 0.0 0.16 10.7 0.0 2.3 1 1 1 2 2 2 1 FAD binding domain DAO PF01266.19 KKK14302.1 - 0.0058 15.5 0.0 0.016 14.1 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KKK14302.1 - 0.0067 16.8 0.0 0.022 15.1 0.0 2.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KKK14302.1 - 0.0083 14.6 0.0 0.014 13.8 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.1 KKK14302.1 - 0.021 14.8 0.0 0.057 13.4 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KKK14302.1 - 0.08 11.8 0.3 0.27 10.0 0.0 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein Dicty_REP PF05086.7 KKK14303.1 - 2.1 5.9 8.0 2.6 5.7 5.5 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF500 PF04366.7 KKK14304.1 - 3.1e-45 152.6 0.0 4.9e-45 152.0 0.0 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF500) Methyltransf_11 PF08241.7 KKK14305.1 - 5.9e-16 58.7 0.0 1.5e-15 57.4 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 KKK14305.1 - 1.1e-14 54.5 0.0 1.5e-14 54.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KKK14305.1 - 8.9e-12 44.8 0.0 1.1e-11 44.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KKK14305.1 - 2.2e-11 44.3 0.0 4.8e-11 43.2 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 KKK14305.1 - 8.1e-11 42.1 0.0 3.6e-10 40.1 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 KKK14305.1 - 7.1e-09 36.0 0.0 1.7e-08 34.8 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 KKK14305.1 - 8.5e-08 32.2 0.0 1.4e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 KKK14305.1 - 5e-06 25.7 0.0 6.1e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.9 KKK14305.1 - 0.00061 19.1 0.0 0.00097 18.5 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase small domain Pox_MCEL PF03291.11 KKK14305.1 - 0.0096 14.8 0.0 0.045 12.6 0.0 1.8 1 1 1 2 2 2 1 mRNA capping enzyme MetW PF07021.7 KKK14305.1 - 0.026 13.8 0.0 0.044 13.1 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_9 PF08003.6 KKK14305.1 - 0.14 10.8 0.0 0.25 10.0 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1698) FmrO PF07091.6 KKK14305.1 - 0.15 10.9 0.0 0.22 10.4 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) FAD_binding_4 PF01565.18 KKK14308.1 - 2.1e-24 85.5 0.1 3.3e-24 84.9 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KKK14308.1 - 0.00066 19.5 0.1 0.0014 18.5 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like Mid2 PF04478.7 KKK14309.1 - 0.00096 18.5 0.0 0.0027 17.1 0.0 1.8 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor YopJ PF03421.11 KKK14309.1 - 0.095 12.5 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 YopJ Serine/Threonine acetyltransferase Pro_isomerase PF00160.16 KKK14310.1 - 1.4e-48 164.9 0.3 1.6e-48 164.8 0.2 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD CBM_4_9 PF02018.12 KKK14312.1 - 1.3e-09 38.1 0.1 1.5e-09 37.9 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate binding domain Spherulin4 PF12138.3 KKK14312.1 - 0.064 12.6 0.0 0.071 12.5 0.0 1.2 1 0 0 1 1 1 0 Spherulation-specific family 4 TDH PF03347.8 KKK14312.1 - 0.068 12.7 0.1 0.092 12.2 0.0 1.2 1 0 0 1 1 1 0 Vibrio thermostable direct hemolysin Sugar_tr PF00083.19 KKK14313.1 - 5.5e-37 127.4 27.7 2.3e-25 89.1 8.5 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 KKK14313.1 - 2.7e-19 69.0 34.0 9.3e-19 67.3 23.6 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.2 KKK14313.1 - 0.012 15.3 3.3 0.13 12.0 0.0 3.8 4 1 0 4 4 4 0 MFS_1 like family PhyH PF05721.8 KKK14314.1 - 3.8e-28 98.9 0.0 4.8e-28 98.6 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_3 PF13640.1 KKK14314.1 - 0.00047 20.6 0.0 0.0011 19.4 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_5 PF13759.1 KKK14314.1 - 0.0022 18.2 0.0 0.005 17.0 0.0 1.6 1 0 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase Aegerolysin PF06355.8 KKK14316.1 - 1.1e-36 125.6 0.4 1.2e-36 125.4 0.3 1.0 1 0 0 1 1 1 1 Aegerolysin Fic PF02661.13 KKK14317.1 - 0.11 13.1 0.1 0.23 12.1 0.1 1.5 1 0 0 1 1 1 0 Fic/DOC family Peptidase_S10 PF00450.17 KKK14319.1 - 2.3e-104 349.8 8.2 2.8e-104 349.5 5.6 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase PHO4 PF01384.15 KKK14320.1 - 2.9e-114 381.0 11.1 3.4e-114 380.8 7.7 1.0 1 0 0 1 1 1 1 Phosphate transporter family PgaD PF13994.1 KKK14320.1 - 0.93 8.9 6.9 0.69 9.4 2.9 2.1 1 1 1 2 2 2 0 PgaD-like protein Aldo_ket_red PF00248.16 KKK14321.1 - 7.6e-50 169.3 0.0 1e-49 168.8 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Reoviridae_Vp9 PF08978.5 KKK14321.1 - 0.06 12.2 0.0 0.089 11.7 0.0 1.1 1 0 0 1 1 1 0 Reoviridae VP9 GMC_oxred_C PF05199.8 KKK14322.1 - 9.9e-10 38.8 0.0 3.5e-09 37.1 0.0 2.0 2 0 0 2 2 2 1 GMC oxidoreductase Abhydrolase_6 PF12697.2 KKK14322.1 - 5.9e-08 32.8 0.0 2.4e-06 27.6 0.0 2.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family GMC_oxred_N PF00732.14 KKK14322.1 - 2.9e-07 29.9 0.0 6.1e-07 28.8 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 KKK14322.1 - 0.00032 19.6 0.7 0.0005 19.0 0.5 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 KKK14322.1 - 0.0014 18.6 0.1 0.0046 16.9 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KKK14322.1 - 0.011 16.1 0.1 0.029 14.7 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KKK14322.1 - 0.037 13.9 0.0 0.069 13.0 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Glyco_transf_56 PF07429.6 KKK14322.1 - 0.071 12.0 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 4-alpha-L-fucosyltransferase glycosyl transferase group 56 FAD_oxidored PF12831.2 KKK14322.1 - 0.82 8.6 4.9 1.4 7.9 3.4 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase cobW PF02492.14 KKK14323.1 - 6.5e-48 162.5 4.9 2.5e-36 124.7 0.6 2.2 1 1 1 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.9 KKK14323.1 - 3.5e-21 74.7 0.3 1.5e-16 59.8 0.0 2.8 3 0 0 3 3 3 2 Cobalamin synthesis protein cobW C-terminal domain MobB PF03205.9 KKK14323.1 - 0.0054 16.4 0.1 0.019 14.6 0.1 2.0 1 1 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B Arch_ATPase PF01637.13 KKK14323.1 - 0.0054 16.4 0.0 0.0082 15.8 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase ArgK PF03308.11 KKK14323.1 - 0.007 15.1 0.5 0.22 10.2 0.0 2.6 2 1 0 2 2 2 1 ArgK protein AAA_33 PF13671.1 KKK14323.1 - 0.0081 16.0 0.2 0.057 13.2 0.1 2.3 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.1 KKK14323.1 - 0.0083 16.2 0.1 0.025 14.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 KKK14323.1 - 0.029 13.8 0.1 0.07 12.6 0.0 1.7 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase UPF0079 PF02367.12 KKK14323.1 - 0.047 13.3 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 T2SE PF00437.15 KKK14323.1 - 0.049 12.5 0.1 0.095 11.5 0.1 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_29 PF13555.1 KKK14323.1 - 0.052 13.0 0.0 0.12 11.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.1 KKK14323.1 - 0.069 13.0 0.0 0.18 11.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 KKK14323.1 - 0.074 13.0 0.2 0.19 11.7 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.1 KKK14323.1 - 0.079 13.2 3.3 0.13 12.5 0.0 2.8 3 0 0 3 3 3 0 AAA domain CbiA PF01656.18 KKK14323.1 - 0.088 12.1 0.9 0.24 10.8 0.6 1.8 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Zeta_toxin PF06414.7 KKK14323.1 - 0.1 11.6 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin HHH_5 PF14520.1 KKK14324.1 - 2.9e-06 27.3 0.0 0.00042 20.4 0.0 2.3 1 1 0 1 1 1 1 Helix-hairpin-helix domain UPF0181 PF03701.9 KKK14324.1 - 0.16 11.2 0.1 0.28 10.4 0.1 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0181) HD PF01966.17 KKK14325.1 - 1.2e-07 31.8 0.0 1.7e-07 31.3 0.0 1.4 1 1 0 1 1 1 1 HD domain HDOD PF08668.7 KKK14325.1 - 0.0025 17.1 0.0 0.0036 16.6 0.0 1.3 1 0 0 1 1 1 1 HDOD domain DUF706 PF05153.10 KKK14325.1 - 0.0041 16.4 0.0 0.0059 15.9 0.0 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF706) HD_4 PF13328.1 KKK14325.1 - 0.049 13.3 0.0 0.11 12.2 0.0 1.6 1 1 0 1 1 1 0 HD domain LRR_6 PF13516.1 KKK14345.1 - 0.04 13.9 0.1 6.1 7.2 0.1 3.8 3 0 0 3 3 3 0 Leucine Rich repeat Kelch_4 PF13418.1 KKK14346.1 - 1e-19 70.0 3.6 3.3e-11 42.7 0.0 5.3 5 1 0 5 5 5 3 Galactose oxidase, central domain Kelch_3 PF13415.1 KKK14346.1 - 3.9e-16 58.7 8.1 4.8e-08 32.9 0.0 5.6 5 1 1 6 6 6 3 Galactose oxidase, central domain Kelch_5 PF13854.1 KKK14346.1 - 4.7e-13 48.7 4.1 5.8e-05 22.9 0.0 4.7 4 1 0 4 4 4 3 Kelch motif Kelch_1 PF01344.20 KKK14346.1 - 8.3e-11 41.2 0.0 0.0089 15.5 0.0 3.7 3 0 0 3 3 3 3 Kelch motif Kelch_2 PF07646.10 KKK14346.1 - 2.2e-10 39.8 2.2 0.0016 18.1 0.0 4.6 3 1 0 3 3 3 3 Kelch motif Kelch_6 PF13964.1 KKK14346.1 - 1.4e-08 34.5 5.8 0.0026 17.8 0.2 5.2 3 1 1 4 4 4 2 Kelch motif AhpC-TSA PF00578.16 KKK14347.1 - 7.6e-35 119.2 0.0 1.3e-34 118.5 0.0 1.4 1 1 0 1 1 1 1 AhpC/TSA family 1-cysPrx_C PF10417.4 KKK14347.1 - 7.6e-17 60.6 0.3 1.2e-16 60.0 0.2 1.3 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Redoxin PF08534.5 KKK14347.1 - 2.5e-13 49.7 0.0 3.4e-13 49.3 0.0 1.2 1 0 0 1 1 1 1 Redoxin EVE PF01878.13 KKK14348.1 - 1.1e-48 164.9 0.0 1.2e-39 135.6 0.0 2.2 1 1 1 2 2 2 2 EVE domain AT_hook PF02178.14 KKK14348.1 - 3.8e-05 22.8 29.1 0.089 12.5 4.6 4.2 3 0 0 3 3 3 3 AT hook motif CTP_transf_2 PF01467.21 KKK14349.1 - 0.016 15.3 4.3 0.58 10.2 3.0 3.0 1 1 0 1 1 1 0 Cytidylyltransferase SGL PF08450.7 KKK14350.1 - 1.1e-80 270.5 0.0 1.4e-80 270.2 0.0 1.1 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Aldedh PF00171.17 KKK14351.1 - 6.6e-187 621.4 0.4 7.4e-187 621.2 0.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 KKK14351.1 - 0.047 12.9 0.0 0.13 11.4 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1487) Pkinase PF00069.20 KKK14358.1 - 7.3e-19 67.9 0.0 9.8e-19 67.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK14358.1 - 8.9e-16 57.7 0.0 1.2e-15 57.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KKK14358.1 - 0.00041 19.4 0.0 0.0012 17.9 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.9 KKK14358.1 - 0.0042 16.1 0.0 0.0062 15.6 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family MFS_1 PF07690.11 KKK14359.1 - 7.2e-06 24.9 2.7 8e-06 24.7 1.9 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KKK14359.1 - 1e-05 24.3 0.1 1.2e-05 24.0 0.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter Pkinase PF00069.20 KKK14360.1 - 9.9e-72 241.1 0.0 1.4e-71 240.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK14360.1 - 1.6e-37 129.0 0.0 4.9e-37 127.3 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KKK14360.1 - 0.003 16.5 1.0 0.69 8.8 0.0 2.7 3 0 0 3 3 3 2 Kinase-like Pox_ser-thr_kin PF05445.6 KKK14360.1 - 0.1 11.3 0.1 0.16 10.7 0.1 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Fungal_trans PF04082.13 KKK14362.1 - 1.4e-13 50.3 1.0 2.2e-13 49.6 0.7 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK14362.1 - 1.4e-06 28.0 10.4 3.1e-06 26.9 7.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1399 PF07173.7 KKK14363.1 - 1.6e-20 73.8 3.9 8.2e-17 61.7 0.1 2.8 3 0 0 3 3 3 2 Protein of unknown function (DUF1399) Pea-VEAacid PF08111.6 KKK14363.1 - 0.64 10.2 3.8 6.9 7.0 0.2 2.7 2 0 0 2 2 2 0 Pea-VEAacid family DUF605 PF04652.11 KKK14364.1 - 9.8 5.4 15.7 13 5.0 10.9 1.1 1 0 0 1 1 1 0 Vta1 like F-box-like PF12937.2 KKK14365.1 - 0.0037 16.9 1.0 0.0063 16.2 0.2 1.8 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KKK14365.1 - 0.011 15.3 0.4 0.026 14.2 0.3 1.7 1 0 0 1 1 1 0 F-box domain TFIIIC_delta PF12657.2 KKK14365.1 - 0.093 12.4 0.1 0.32 10.6 0.0 1.9 2 0 0 2 2 2 0 Transcription factor IIIC subunit delta N-term Fungal_trans PF04082.13 KKK14366.1 - 3.2e-19 68.8 0.1 9.8e-19 67.2 0.1 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK14366.1 - 1.3e-06 28.1 7.0 3e-06 27.0 4.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Alpha-L-AF_C PF06964.7 KKK14377.1 - 1.1e-49 168.5 0.0 1.7e-49 167.9 0.0 1.3 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminus Pectate_lyase PF03211.8 KKK14378.1 - 8.5e-61 205.0 3.1 1.1e-60 204.7 2.2 1.0 1 0 0 1 1 1 1 Pectate lyase MIP PF00230.15 KKK14379.1 - 1.1e-40 139.5 6.6 1.5e-40 139.0 4.6 1.1 1 0 0 1 1 1 1 Major intrinsic protein DUF1212 PF06738.7 KKK14379.1 - 2 7.8 4.3 12 5.3 2.9 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1212) PP-binding PF00550.20 KKK14380.1 - 1.1e-06 28.7 0.0 2.4e-06 27.7 0.0 1.6 2 0 0 2 2 2 1 Phosphopantetheine attachment site Condensation PF00668.15 KKK14380.1 - 0.0074 15.1 0.0 0.012 14.4 0.0 1.4 1 0 0 1 1 1 1 Condensation domain ketoacyl-synt PF00109.21 KKK14381.1 - 2e-65 220.8 0.1 1.1e-64 218.3 0.0 2.0 1 1 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 KKK14381.1 - 2.4e-51 173.9 0.1 5.4e-51 172.8 0.1 1.7 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 KKK14381.1 - 3.3e-37 127.9 0.5 1.1e-36 126.2 0.1 2.2 2 0 0 2 2 2 1 short chain dehydrogenase ADH_zinc_N PF00107.21 KKK14381.1 - 2.3e-18 65.9 0.0 8.8e-18 64.0 0.0 2.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KKK14381.1 - 9e-14 52.4 0.0 7.9e-13 49.4 0.0 2.4 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.7 KKK14381.1 - 9.1e-10 38.9 0.0 3.2e-09 37.1 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KKK14381.1 - 8.2e-09 35.3 0.0 1.6e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KKK14381.1 - 8.1e-07 29.4 0.0 2.5e-06 27.8 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KKK14381.1 - 9.1e-07 28.5 0.0 2.4e-06 27.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KKK14381.1 - 0.0013 17.9 0.0 0.0031 16.6 0.0 1.6 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 KKK14381.1 - 0.0028 18.2 0.0 0.014 15.9 0.0 2.2 2 0 0 2 2 1 1 Methyltransferase domain ADH_N PF08240.7 KKK14381.1 - 0.0058 16.3 2.9 0.0082 15.8 0.0 2.6 3 1 0 3 3 2 1 Alcohol dehydrogenase GroES-like domain Thiolase_N PF00108.18 KKK14381.1 - 0.022 13.7 0.0 0.042 12.8 0.0 1.4 1 0 0 1 1 1 0 Thiolase, N-terminal domain DNA_gyraseB_C PF00986.16 KKK14381.1 - 0.13 12.0 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 DNA gyrase B subunit, carboxyl terminus Methyltransf_16 PF10294.4 KKK14381.1 - 0.16 11.4 0.0 0.85 9.0 0.0 2.1 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_8 PF05148.10 KKK14381.1 - 0.33 10.5 0.0 0.75 9.3 0.0 1.5 1 0 0 1 1 1 0 Hypothetical methyltransferase Metallophos PF00149.23 KKK14382.1 - 1.7e-08 34.1 0.0 5.2e-08 32.5 0.0 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KKK14382.1 - 2.6e-05 24.1 0.1 0.0001 22.1 0.0 2.1 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain PBP_like_2 PF12849.2 KKK14383.1 - 1.1e-09 38.1 5.3 1.5e-09 37.7 3.7 1.1 1 0 0 1 1 1 1 PBP superfamily domain Transferase PF02458.10 KKK14384.1 - 3e-07 29.2 0.0 0.00018 20.0 0.0 2.2 2 1 0 2 2 2 2 Transferase family MFS_1 PF07690.11 KKK14386.1 - 9.9e-21 73.8 23.6 9.9e-21 73.8 16.4 2.4 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KKK14386.1 - 3.8e-05 22.4 27.8 0.0003 19.4 19.3 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter Peptidase_M56 PF05569.6 KKK14386.1 - 0.098 11.6 1.8 0.16 10.9 0.1 2.0 2 0 0 2 2 2 0 BlaR1 peptidase M56 E1-E2_ATPase PF00122.15 KKK14387.1 - 3e-50 170.4 5.2 3e-50 170.4 3.6 2.8 2 1 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KKK14387.1 - 2e-26 92.6 2.3 2e-26 92.6 1.6 2.7 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KKK14387.1 - 6e-23 82.3 0.0 2.3e-22 80.4 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KKK14387.1 - 3.8e-16 58.8 0.0 8.8e-16 57.6 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 KKK14387.1 - 1.9e-11 44.4 0.0 3.8e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KKK14387.1 - 1.2e-06 27.8 0.0 4.8e-06 25.9 0.0 2.1 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 KKK14387.1 - 1.9e-05 24.3 0.3 0.00059 19.4 0.1 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HsbA PF12296.3 KKK14388.1 - 1.3e-24 86.4 6.8 2e-24 85.8 4.7 1.3 1 0 0 1 1 1 1 Hydrophobic surface binding protein A Sec1 PF00995.18 KKK14389.1 - 4.1e-157 524.2 0.0 4.8e-157 523.9 0.0 1.0 1 0 0 1 1 1 1 Sec1 family RNA_lig_T4_1 PF09511.5 KKK14389.1 - 0.033 13.6 0.3 0.053 12.9 0.2 1.3 1 0 0 1 1 1 0 RNA ligase zf-CCCH PF00642.19 KKK14390.1 - 0.0046 16.6 0.7 0.0075 15.9 0.5 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) HORMA PF02301.13 KKK14391.1 - 7.7e-50 169.2 0.3 8.7e-50 169.0 0.2 1.0 1 0 0 1 1 1 1 HORMA domain SspB PF04386.8 KKK14391.1 - 0.53 9.8 5.3 0.82 9.2 0.0 2.6 2 1 1 3 3 3 0 Stringent starvation protein B RNA_pol_Rpb1_5 PF04998.12 KKK14392.1 - 1.9e-90 302.8 1.4 3.5e-90 302.0 1.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.7 KKK14392.1 - 9.1e-84 281.5 0.0 1.3e-83 281.0 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.15 KKK14392.1 - 1.1e-66 223.8 0.0 3.1e-66 222.4 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 GTP_EFTU PF00009.22 KKK14392.1 - 1.4e-39 135.5 0.0 3.9e-38 130.7 0.0 2.4 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain LepA_C PF06421.7 KKK14392.1 - 1.7e-36 124.3 1.2 4.9e-36 122.9 0.8 1.8 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus RNA_pol_Rpb1_3 PF04983.13 KKK14392.1 - 1.8e-33 115.4 0.0 6.8e-33 113.6 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 KKK14392.1 - 2.8e-27 94.5 0.1 7e-27 93.3 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 EFG_C PF00679.19 KKK14392.1 - 1.5e-19 69.6 0.0 1.7e-18 66.2 0.0 2.5 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 KKK14392.1 - 0.0001 22.3 0.2 0.00043 20.3 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_II PF14492.1 KKK14392.1 - 0.026 14.3 0.0 0.08 12.8 0.0 1.9 1 0 0 1 1 1 0 Elongation Factor G, domain II Aldo_ket_red PF00248.16 KKK14393.1 - 9.7e-40 136.1 0.1 3.3e-25 88.4 0.0 2.1 2 0 0 2 2 2 2 Aldo/keto reductase family BAR PF03114.13 KKK14394.1 - 6.8e-66 222.0 6.0 8.6e-66 221.7 4.1 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.23 KKK14394.1 - 2.9e-15 55.3 0.0 5.1e-15 54.5 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KKK14394.1 - 3e-14 52.3 0.0 5.1e-14 51.5 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KKK14394.1 - 1.9e-10 40.0 0.0 4.4e-10 38.8 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain GldM_N PF12081.3 KKK14394.1 - 0.066 12.7 4.2 0.96 8.9 0.8 2.3 2 0 0 2 2 2 0 GldM N-terminal domain Vps5 PF09325.5 KKK14394.1 - 0.091 11.9 5.6 1.9 7.6 0.1 2.2 2 0 0 2 2 2 0 Vps5 C terminal like Retinal PF15449.1 KKK14394.1 - 0.12 10.0 2.3 0.18 9.4 1.6 1.2 1 0 0 1 1 1 0 Retinal protein Tropomyosin PF00261.15 KKK14394.1 - 0.25 10.3 11.2 1.1 8.2 0.2 2.3 2 0 0 2 2 2 0 Tropomyosin APG6 PF04111.7 KKK14394.1 - 0.76 8.7 8.0 3.3 6.6 2.5 2.1 2 0 0 2 2 2 0 Autophagy protein Apg6 Aminotran_5 PF00266.14 KKK14395.1 - 1.6e-96 323.2 0.0 2e-96 322.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 KKK14395.1 - 5.2e-07 29.1 0.0 8.1e-07 28.4 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 KKK14395.1 - 0.00078 18.5 0.0 0.0015 17.6 0.0 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.14 KKK14395.1 - 0.00079 17.9 0.0 0.0011 17.4 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain IDO PF01231.13 KKK14396.1 - 5.4e-149 496.2 0.0 6.1e-149 496.0 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase Epimerase PF01370.16 KKK14397.1 - 4.6e-11 42.5 0.0 1.3e-09 37.8 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KKK14397.1 - 5.1e-07 29.8 0.0 8.7e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 KKK14397.1 - 4.8e-06 25.6 0.5 0.00091 18.2 0.1 2.9 1 1 1 2 2 2 1 Male sterility protein 3Beta_HSD PF01073.14 KKK14397.1 - 1.7e-05 23.6 0.0 0.00011 21.0 0.0 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 KKK14397.1 - 0.0029 16.5 0.0 0.0045 15.9 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.8 KKK14397.1 - 0.004 16.4 0.0 0.0064 15.7 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.19 KKK14397.1 - 0.013 15.8 0.0 0.024 14.9 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain AA_permease PF00324.16 KKK14398.1 - 4.5e-141 470.4 40.1 5e-141 470.2 27.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KKK14398.1 - 2.2e-37 128.6 40.8 2.8e-37 128.2 28.3 1.1 1 0 0 1 1 1 1 Amino acid permease CATSPERD PF15020.1 KKK14398.1 - 2.8 5.8 4.5 8.7 4.2 0.0 2.1 2 0 0 2 2 2 0 Cation channel sperm-associated protein subunit delta Fungal_trans_2 PF11951.3 KKK14399.1 - 1e-06 27.6 0.0 2e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK14399.1 - 1.4e-06 28.0 10.9 2.6e-06 27.2 7.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.17 KKK14400.1 - 1e-47 162.7 0.0 1.3e-47 162.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 AA_permease_2 PF13520.1 KKK14401.1 - 4.6e-64 216.5 34.5 5.6e-64 216.2 23.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KKK14401.1 - 6.5e-15 54.4 32.3 8.1e-15 54.1 22.4 1.0 1 0 0 1 1 1 1 Amino acid permease MAPEG PF01124.13 KKK14402.1 - 1.1e-14 54.0 1.7 1.6e-14 53.6 1.2 1.1 1 0 0 1 1 1 1 MAPEG family Flp_Fap PF04964.9 KKK14402.1 - 0.085 12.4 0.1 0.18 11.4 0.1 1.6 1 0 0 1 1 1 0 Flp/Fap pilin component STE2 PF02116.10 KKK14404.1 - 3.5e-99 331.4 13.4 4.1e-99 331.1 9.3 1.0 1 0 0 1 1 1 1 Fungal pheromone mating factor STE2 GPCR PufQ PF05398.6 KKK14404.1 - 0.13 12.3 1.0 7.7 6.6 0.1 2.5 1 1 1 2 2 2 0 PufQ cytochrome subunit APH PF01636.18 KKK14405.1 - 0.035 13.8 0.3 0.074 12.7 0.2 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family Beta_helix PF13229.1 KKK14406.1 - 7.6e-08 32.2 13.2 2.5e-06 27.3 4.7 2.7 2 1 1 3 3 3 2 Right handed beta helix region DUF1565 PF07602.6 KKK14406.1 - 0.0049 16.0 0.3 0.0096 15.0 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1565) Chondroitinas_B PF14592.1 KKK14406.1 - 0.014 14.2 0.0 0.023 13.5 0.0 1.2 1 0 0 1 1 1 0 Chondroitinase B DIOX_N PF14226.1 KKK14407.1 - 1.4e-33 115.8 0.0 1.8e-30 105.8 0.0 2.2 2 0 0 2 2 2 2 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KKK14407.1 - 7.6e-14 51.8 0.0 1.6e-13 50.7 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Cu_amine_oxid PF01179.15 KKK14408.1 - 6.5e-162 538.9 0.0 7.9e-162 538.6 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.11 KKK14408.1 - 5.5e-07 29.5 0.0 1.2e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.11 KKK14408.1 - 2.9e-05 24.0 0.1 6.4e-05 22.9 0.1 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain MFS_1 PF07690.11 KKK14409.1 - 1.3e-37 129.3 49.9 7e-37 126.9 34.6 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 KKK14409.1 - 0.00015 20.1 23.6 0.0003 19.1 16.4 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF2937 PF11157.3 KKK14409.1 - 0.0036 16.6 2.6 0.026 13.8 0.2 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2937) Glyco_hydro_43 PF04616.9 KKK14410.1 - 3.6e-36 124.7 4.7 4.6e-36 124.3 3.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 TNF PF00229.13 KKK14410.1 - 0.022 14.2 1.0 4.1 6.9 0.1 2.3 2 0 0 2 2 2 0 TNF(Tumour Necrosis Factor) family C1q PF00386.16 KKK14410.1 - 0.069 13.1 1.1 7.1 6.6 0.1 2.6 2 0 0 2 2 2 0 C1q domain Fungal_trans PF04082.13 KKK14411.1 - 1.2e-15 57.0 0.2 9e-15 54.2 0.0 2.2 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK14411.1 - 2.9e-08 33.4 10.2 5.3e-08 32.6 7.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SlyX PF04102.7 KKK14411.1 - 0.15 12.4 1.1 0.4 11.0 0.0 2.2 2 0 0 2 2 2 0 SlyX HSP20 PF00011.16 KKK14412.1 - 9.4e-19 67.1 0.9 2.8e-16 59.2 0.6 2.2 1 1 0 1 1 1 1 Hsp20/alpha crystallin family ECH PF00378.15 KKK14413.1 - 2.1e-35 122.0 0.7 2.2e-26 92.4 0.1 2.2 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase family Sigma70_ner PF04546.8 KKK14413.1 - 0.082 12.5 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region Tbf5 PF06331.7 KKK14414.1 - 4.1e-26 90.5 0.3 4.6e-26 90.3 0.2 1.0 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 DJ-1_PfpI PF01965.19 KKK14415.1 - 5.1e-16 58.4 0.0 9.1e-16 57.6 0.0 1.4 1 1 0 1 1 1 1 DJ-1/PfpI family DJ-1_PfpI_N PF13587.1 KKK14415.1 - 9.8e-05 21.8 0.0 0.00024 20.5 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of DJ-1_PfpI family IlvN PF07991.7 KKK14416.1 - 6.5e-46 155.7 0.0 9.3e-46 155.2 0.0 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain IlvC PF01450.14 KKK14416.1 - 5.8e-45 152.7 0.0 1.1e-44 151.8 0.0 1.5 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_2 PF03446.10 KKK14416.1 - 0.014 15.2 0.0 0.024 14.4 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 KKK14416.1 - 0.083 13.3 0.0 0.21 12.0 0.0 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Isochorismatase PF00857.15 KKK14417.1 - 3.4e-21 75.9 0.0 4.8e-20 72.1 0.0 2.7 1 1 1 2 2 2 1 Isochorismatase family 2OG-FeII_Oxy_2 PF13532.1 KKK14417.1 - 1.6e-20 73.7 0.0 2.8e-20 72.9 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily GST_C_3 PF14497.1 KKK14417.1 - 1.2e-06 28.8 0.0 3.1e-06 27.5 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KKK14417.1 - 1e-05 25.4 0.0 1.9e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KKK14417.1 - 6.2e-05 22.8 0.0 0.00016 21.4 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain TAF8_C PF10406.4 KKK14418.1 - 7e-22 77.2 1.3 1.5e-21 76.1 0.9 1.6 1 0 0 1 1 1 1 Transcription factor TFIID complex subunit 8 C-term Bromo_TP PF07524.8 KKK14418.1 - 9.7e-10 38.0 0.0 4.9e-09 35.7 0.0 1.9 2 0 0 2 2 2 1 Bromodomain associated Mitochondr_Som1 PF11093.3 KKK14419.1 - 6.7e-12 45.0 0.0 9.3e-12 44.5 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial export protein Som1 Rad51 PF08423.6 KKK14420.1 - 7.3e-05 21.7 0.0 0.0052 15.7 0.0 2.2 2 0 0 2 2 2 2 Rad51 DUF4276 PF14103.1 KKK14420.1 - 0.086 12.6 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4276) PALP PF00291.20 KKK14421.1 - 6.6e-78 262.0 0.4 8.1e-78 261.7 0.3 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Aminotran_1_2 PF00155.16 KKK14421.1 - 0.0087 15.0 0.0 0.17 10.7 0.0 2.2 2 0 0 2 2 2 1 Aminotransferase class I and II UEV PF05743.8 KKK14422.1 - 3.9e-39 133.0 0.1 6.1e-39 132.4 0.1 1.3 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.5 KKK14422.1 - 5.7e-23 80.3 0.0 1.2e-22 79.2 0.0 1.6 1 0 0 1 1 1 1 Vps23 core domain UQ_con PF00179.21 KKK14422.1 - 0.0022 17.3 0.1 0.0052 16.2 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme KLRAQ PF10205.4 KKK14422.1 - 0.075 13.0 0.4 0.15 12.1 0.3 1.4 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein TMF_TATA_bd PF12325.3 KKK14422.1 - 0.084 12.6 1.4 0.15 11.7 1.0 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Reo_sigmaC PF04582.7 KKK14422.1 - 0.21 10.7 5.6 0.32 10.1 3.9 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Chitin_synth_1 PF01644.12 KKK14423.1 - 1.6e-68 229.6 0.0 3.6e-68 228.4 0.0 1.6 2 0 0 2 2 2 1 Chitin synthase UQ_con PF00179.21 KKK14423.1 - 2e-36 124.4 0.0 3.6e-36 123.6 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Chitin_synth_1N PF08407.6 KKK14423.1 - 2.2e-27 94.5 0.1 4.1e-27 93.6 0.0 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 KKK14423.1 - 5.5e-25 87.7 0.0 2e-21 75.9 0.0 2.1 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 KKK14423.1 - 8.9e-13 48.3 0.1 8.9e-13 48.3 0.0 2.7 4 1 0 4 4 4 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 KKK14423.1 - 2.1e-09 37.5 0.0 6.6e-09 35.9 0.0 1.9 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Opy2 PF09463.5 KKK14425.1 - 2.1e-11 43.7 23.7 3.4e-11 43.0 16.4 1.4 1 0 0 1 1 1 1 Opy2 protein Syndecan PF01034.15 KKK14425.1 - 0.0016 18.0 0.0 0.003 17.1 0.0 1.3 1 0 0 1 1 1 1 Syndecan domain SKG6 PF08693.5 KKK14425.1 - 0.039 13.2 1.0 0.088 12.1 0.7 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF912 PF06024.7 KKK14425.1 - 0.13 12.3 0.0 0.93 9.5 0.0 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) YebO PF13974.1 KKK14425.1 - 0.14 11.9 0.1 0.37 10.5 0.0 1.8 1 0 0 1 1 1 0 YebO-like protein Mid2 PF04478.7 KKK14425.1 - 0.26 10.6 2.2 0.3 10.4 0.0 2.0 2 0 0 2 2 2 0 Mid2 like cell wall stress sensor Beta-APP PF03494.8 KKK14425.1 - 8.9 5.8 6.8 16 5.1 4.7 1.4 1 0 0 1 1 1 0 Beta-amyloid peptide (beta-APP) Velvet PF11754.3 KKK14426.1 - 0.069 12.7 0.0 0.082 12.5 0.0 1.1 1 0 0 1 1 1 0 Velvet factor FAD_binding_4 PF01565.18 KKK14497.1 - 6e-18 64.6 0.4 1.5e-17 63.3 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 KKK14497.1 - 4.6e-09 36.0 0.0 1e-08 34.9 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like ZZ PF00569.12 KKK14500.1 - 1.2e-20 72.7 49.6 6.7e-07 28.7 5.8 4.3 4 0 0 4 4 4 4 Zinc finger, ZZ type Drf_GBD PF06371.8 KKK14516.1 - 1.3e-16 60.5 1.9 3.6e-15 55.8 1.3 2.4 1 1 0 1 1 1 1 Diaphanous GTPase-binding Domain Nramp PF01566.13 KKK14518.1 - 1e-93 314.0 21.3 1e-93 314.0 14.8 1.3 2 0 0 2 2 2 1 Natural resistance-associated macrophage protein Snf7 PF03357.16 KKK14519.1 - 7.9e-44 149.0 15.3 9.6e-44 148.7 10.6 1.0 1 0 0 1 1 1 1 Snf7 DUF4201 PF13870.1 KKK14519.1 - 0.002 17.5 6.1 0.002 17.5 4.2 1.8 1 1 1 2 2 2 1 Domain of unknown function (DUF4201) Prefoldin_2 PF01920.15 KKK14519.1 - 0.006 16.3 7.5 0.072 12.8 0.0 3.5 2 1 1 3 3 3 1 Prefoldin subunit NPV_P10 PF05531.7 KKK14519.1 - 0.016 15.4 5.6 0.14 12.3 0.4 2.7 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Y_phosphatase3C PF13348.1 KKK14519.1 - 0.018 15.1 0.0 0.1 12.7 0.0 2.3 2 0 0 2 2 2 0 Tyrosine phosphatase family C-terminal region Sec34 PF04136.10 KKK14519.1 - 0.023 14.4 5.4 0.61 9.7 1.6 2.2 1 1 1 2 2 2 0 Sec34-like family Reo_sigmaC PF04582.7 KKK14519.1 - 0.036 13.2 3.6 0.096 11.8 0.5 2.0 1 1 1 2 2 2 0 Reovirus sigma C capsid protein HHH_2 PF12826.2 KKK14519.1 - 0.045 13.6 0.0 0.089 12.6 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix motif DUF1395 PF07160.7 KKK14519.1 - 0.075 12.5 5.2 0.19 11.2 1.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1395) Tropomyosin_1 PF12718.2 KKK14519.1 - 0.16 11.8 0.2 0.16 11.8 0.1 2.3 1 1 1 2 2 2 0 Tropomyosin like IncA PF04156.9 KKK14519.1 - 0.22 11.0 5.2 0.74 9.3 0.5 2.3 1 1 1 2 2 2 0 IncA protein Atg14 PF10186.4 KKK14519.1 - 0.25 10.2 6.9 0.35 9.7 4.8 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Mod_r PF07200.8 KKK14519.1 - 0.59 10.0 9.2 0.11 12.4 2.4 2.1 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein MitMem_reg PF13012.1 KKK14519.1 - 0.7 10.0 4.9 2.2 8.3 3.2 1.9 1 1 1 2 2 2 0 Maintenance of mitochondrial structure and function DUF4140 PF13600.1 KKK14519.1 - 1.1 9.7 4.1 3.1 8.2 0.0 3.1 2 1 2 4 4 4 0 N-terminal domain of unknown function (DUF4140) FlaC_arch PF05377.6 KKK14519.1 - 1.2 9.1 4.8 24 4.9 0.9 2.9 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) DUF4337 PF14235.1 KKK14519.1 - 1.2 9.0 6.9 0.26 11.1 1.9 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4337) DUF4094 PF13334.1 KKK14519.1 - 1.3 9.4 4.7 40 4.6 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) OmpH PF03938.9 KKK14519.1 - 1.4 8.8 12.8 1.1 9.1 6.1 2.0 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) DUF4355 PF14265.1 KKK14519.1 - 1.4 8.8 8.5 0.46 10.4 3.9 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4355) SYCE1 PF15233.1 KKK14519.1 - 1.6 8.6 7.3 8 6.3 5.0 1.9 1 1 0 1 1 1 0 Synaptonemal complex central element protein 1 DUF342 PF03961.8 KKK14519.1 - 2 6.7 8.7 1.4 7.2 1.6 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF342) FliD_N PF02465.13 KKK14519.1 - 6.7 7.1 9.6 14 6.0 3.7 2.7 1 1 2 3 3 3 0 Flagellar hook-associated protein 2 N-terminus V-ATPase_C PF03223.10 KKK14520.1 - 2.2e-85 286.7 0.0 2.7e-85 286.5 0.0 1.0 1 0 0 1 1 1 1 V-ATPase subunit C GHL13 PF14883.1 KKK14520.1 - 0.092 11.8 0.1 0.13 11.3 0.1 1.2 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase family 13 COXG PF06240.8 KKK14520.1 - 0.12 11.9 0.1 0.27 10.8 0.0 1.6 2 0 0 2 2 2 0 Carbon monoxide dehydrogenase subunit G (CoxG) APS_kinase PF01583.15 KKK14521.1 - 4.3e-70 234.4 0.0 5.2e-70 234.1 0.0 1.1 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.1 KKK14521.1 - 7.4e-07 29.1 0.0 1.3e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KKK14521.1 - 6.9e-05 23.6 0.0 0.00012 22.8 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KKK14521.1 - 8.1e-05 22.9 0.0 0.00015 22.1 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KKK14521.1 - 0.0011 18.9 0.1 0.0022 17.9 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain KTI12 PF08433.5 KKK14521.1 - 0.0013 17.9 0.0 0.0021 17.3 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_29 PF13555.1 KKK14521.1 - 0.069 12.6 0.1 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain Zeta_toxin PF06414.7 KKK14521.1 - 0.11 11.5 0.0 0.19 10.8 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin BRO1 PF03097.13 KKK14530.1 - 1.4e-123 412.4 0.1 1.4e-123 412.4 0.1 2.0 3 0 0 3 3 3 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 KKK14530.1 - 8.9e-77 257.9 20.0 5.1e-57 193.0 3.0 2.6 2 1 1 3 3 3 2 ALIX V-shaped domain binding to HIV CTDII PF01556.13 KKK14530.1 - 3.1e-27 94.2 0.7 1.5e-20 72.8 0.1 3.3 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ PF00226.26 KKK14530.1 - 2.4e-23 81.6 1.1 8.3e-23 79.9 0.7 2.0 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 KKK14530.1 - 6.5e-11 42.1 20.3 1.2e-10 41.2 14.1 1.5 1 0 0 1 1 1 1 DnaJ central domain Lon_C PF05362.8 KKK14531.1 - 7.2e-52 175.6 0.0 1.2e-51 174.9 0.0 1.4 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON PF02190.11 KKK14531.1 - 7.7e-37 126.9 0.0 1.8e-36 125.7 0.0 1.7 1 0 0 1 1 1 1 ATP-dependent protease La (LON) domain AAA PF00004.24 KKK14531.1 - 6.3e-22 78.1 0.0 1.5e-21 76.9 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KKK14531.1 - 2.4e-07 30.5 0.0 4.6e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 KKK14531.1 - 1.9e-06 27.9 0.0 5.6e-06 26.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 KKK14531.1 - 7.2e-06 26.1 0.1 0.00012 22.2 0.1 2.5 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KKK14531.1 - 8.1e-06 26.6 0.0 3.5e-05 24.6 0.0 2.1 1 0 0 1 1 1 1 AAA domain ChlI PF13541.1 KKK14531.1 - 2.7e-05 23.6 0.0 0.0001 21.8 0.0 2.0 1 1 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_PrkA PF08298.6 KKK14531.1 - 2.9e-05 22.9 0.2 6.6e-05 21.7 0.0 1.6 2 0 0 2 2 2 1 PrkA AAA domain AAA_16 PF13191.1 KKK14531.1 - 5e-05 23.3 0.0 0.00022 21.2 0.0 2.1 1 1 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.7 KKK14531.1 - 0.00031 19.8 0.0 0.0014 17.7 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_18 PF13238.1 KKK14531.1 - 0.00076 19.7 1.9 0.0026 18.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 KKK14531.1 - 0.0015 18.4 0.0 0.0036 17.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain ATP-synt_ab PF00006.20 KKK14531.1 - 0.0084 15.6 0.0 0.044 13.2 0.0 2.1 3 0 0 3 3 2 1 ATP synthase alpha/beta family, nucleotide-binding domain IstB_IS21 PF01695.12 KKK14531.1 - 0.017 14.5 0.0 0.039 13.3 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein TIP49 PF06068.8 KKK14531.1 - 0.018 13.7 0.2 0.21 10.2 0.0 2.2 2 0 0 2 2 2 0 TIP49 C-terminus NTPase_1 PF03266.10 KKK14531.1 - 0.024 14.3 0.2 0.26 11.0 0.0 2.5 1 1 1 2 2 2 0 NTPase RNA_helicase PF00910.17 KKK14531.1 - 0.03 14.4 0.0 0.11 12.6 0.0 2.0 1 0 0 1 1 1 0 RNA helicase DUF258 PF03193.11 KKK14531.1 - 0.038 13.1 0.0 0.086 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_25 PF13481.1 KKK14531.1 - 0.052 12.9 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 KKK14531.1 - 0.057 13.1 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B UPF0079 PF02367.12 KKK14531.1 - 0.071 12.7 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_33 PF13671.1 KKK14531.1 - 0.12 12.2 0.0 0.31 10.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 KKK14531.1 - 0.12 12.6 1.6 0.27 11.5 0.0 2.3 2 0 0 2 2 2 0 ABC transporter NACHT PF05729.7 KKK14531.1 - 0.14 11.8 0.0 0.59 9.7 0.0 2.0 2 0 0 2 2 2 0 NACHT domain Pkinase PF00069.20 KKK14532.1 - 1.9e-10 40.3 0.0 3.7e-09 36.1 0.0 2.5 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK14532.1 - 1e-09 37.8 0.0 7.5e-09 35.0 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase cobW PF02492.14 KKK14533.1 - 5.3e-19 68.3 0.0 7.9e-19 67.7 0.0 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.9 KKK14533.1 - 6.3e-06 25.8 0.0 1.1e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain SAP30_Sin3_bdg PF13867.1 KKK14534.1 - 1e-13 50.8 0.2 5.5e-13 48.5 0.0 2.1 2 0 0 2 2 2 1 Sin3 binding region of histone deacetylase complex subunit SAP30 Pyr_redox_2 PF07992.9 KKK14538.1 - 1.7e-29 103.1 0.2 2.1e-29 102.8 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KKK14538.1 - 5.5e-14 52.3 0.5 1.2e-13 51.2 0.3 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KKK14538.1 - 0.00018 20.5 0.0 0.00024 20.1 0.0 1.3 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) 3HCDH_N PF02737.13 KKK14538.1 - 0.00018 21.2 0.5 0.00033 20.3 0.3 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.1 KKK14538.1 - 0.00034 20.7 0.0 0.00055 20.0 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pkinase PF00069.20 KKK14539.1 - 1.1e-50 172.2 0.0 3.3e-49 167.3 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK14539.1 - 3.6e-31 108.1 0.0 2e-30 105.7 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Seadorna_VP7 PF07387.6 KKK14539.1 - 0.0036 16.1 0.1 0.0068 15.2 0.1 1.4 1 0 0 1 1 1 1 Seadornavirus VP7 Kinase-like PF14531.1 KKK14539.1 - 0.0049 15.8 0.0 0.0076 15.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pox_ser-thr_kin PF05445.6 KKK14539.1 - 0.089 11.5 0.1 0.13 11.0 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Peptidase_C12 PF01088.16 KKK14540.1 - 1.3e-47 161.7 0.0 3.2e-47 160.4 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Kei1 PF08552.6 KKK14540.1 - 0.033 13.8 0.1 0.049 13.2 0.1 1.2 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Zn_clus PF00172.13 KKK14541.1 - 5.7e-08 32.5 13.2 5.7e-08 32.5 9.1 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KKK14541.1 - 2.1e-06 26.5 1.8 3.2e-06 26.0 1.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Mem_trans PF03547.13 KKK14542.1 - 1.5e-56 191.3 0.1 1.9e-56 191.0 0.1 1.1 1 0 0 1 1 1 1 Membrane transport protein NODP PF07684.7 KKK14542.1 - 0.053 13.1 0.1 0.12 11.9 0.1 1.6 1 0 0 1 1 1 0 NOTCH protein Choline_kinase PF01633.15 KKK14543.1 - 2.7e-59 200.2 0.0 5.8e-59 199.1 0.0 1.6 2 0 0 2 2 2 1 Choline/ethanolamine kinase Choline_kin_N PF04428.9 KKK14543.1 - 3.1e-15 55.3 0.0 7.2e-15 54.1 0.0 1.6 1 0 0 1 1 1 1 Choline kinase N terminus APH PF01636.18 KKK14543.1 - 5.8e-08 32.7 0.6 1.6e-07 31.3 0.4 1.8 1 0 0 1 1 1 1 Phosphotransferase enzyme family ATP11 PF06644.6 KKK14573.1 - 4.9e-89 298.3 0.0 5.7e-89 298.1 0.0 1.0 1 0 0 1 1 1 1 ATP11 protein zf-C4H2 PF10146.4 KKK14573.1 - 0.26 11.2 5.3 0.18 11.7 2.5 1.6 1 1 1 2 2 2 0 Zinc finger-containing protein CAP_N PF01213.14 KKK14573.1 - 1.1 8.4 9.1 1.9 7.6 6.3 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg PF05308.6 KKK14573.1 - 4.4 6.5 13.6 5.8 6.2 8.3 1.9 1 1 1 2 2 2 0 Mitochondrial fission regulator Evr1_Alr PF04777.8 KKK14574.1 - 9.7e-27 92.7 0.0 2.8e-26 91.2 0.0 1.9 1 0 0 1 1 1 1 Erv1 / Alr family zf-LYAR PF08790.6 KKK14574.1 - 4.4e-13 48.6 3.2 4.4e-13 48.6 2.2 1.9 2 0 0 2 2 2 1 LYAR-type C2HC zinc finger zf-RING_2 PF13639.1 KKK14575.1 - 2e-05 24.3 1.2 3.4e-05 23.5 0.9 1.3 1 0 0 1 1 1 1 Ring finger domain Prok-RING_1 PF14446.1 KKK14575.1 - 0.0017 18.0 0.9 0.0029 17.3 0.6 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 C1_1 PF00130.17 KKK14575.1 - 0.0022 17.6 1.0 0.0037 16.9 0.7 1.3 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) FYVE PF01363.16 KKK14575.1 - 0.013 15.4 0.2 0.024 14.5 0.1 1.4 1 0 0 1 1 1 0 FYVE zinc finger zf-rbx1 PF12678.2 KKK14575.1 - 0.076 13.1 2.2 0.15 12.2 1.5 1.4 1 0 0 1 1 1 0 RING-H2 zinc finger PHD PF00628.24 KKK14575.1 - 0.12 12.1 1.2 0.23 11.1 0.8 1.5 1 0 0 1 1 1 0 PHD-finger R3H PF01424.17 KKK14576.1 - 6.4e-10 38.5 0.1 1.4e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 R3H domain Trypan_PARP PF05887.6 KKK14576.1 - 0.13 12.0 13.6 0.31 10.8 9.5 1.6 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Zip PF02535.17 KKK14576.1 - 0.18 10.7 7.2 0.28 10.1 5.0 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter SelP_N PF04592.9 KKK14576.1 - 0.2 11.0 16.3 0.34 10.2 11.3 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region SAPS PF04499.10 KKK14576.1 - 0.39 9.2 3.6 0.58 8.7 2.5 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein MFS_1 PF07690.11 KKK14577.1 - 1.5e-17 63.4 56.4 1.2e-16 60.4 35.6 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF2976 PF11190.3 KKK14577.1 - 0.00027 20.4 4.7 0.0018 17.7 0.3 3.7 3 0 0 3 3 3 1 Protein of unknown function (DUF2976) Na_Pi_cotrans PF02690.10 KKK14577.1 - 0.78 9.4 14.5 0.84 9.3 1.1 3.9 3 1 1 4 4 4 0 Na+/Pi-cotransporter Fungal_trans_2 PF11951.3 KKK14578.1 - 3.4e-07 29.2 0.1 5.2e-07 28.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain SF-assemblin PF06705.6 KKK14578.1 - 0.043 12.9 0.0 0.065 12.3 0.0 1.1 1 0 0 1 1 1 0 SF-assemblin/beta giardin AATase PF07247.7 KKK14579.1 - 5.2e-05 21.9 0.0 0.00025 19.7 0.0 1.8 1 1 0 1 1 1 1 Alcohol acetyltransferase Condensation PF00668.15 KKK14579.1 - 0.025 13.4 0.0 0.049 12.4 0.0 1.5 1 0 0 1 1 1 0 Condensation domain DUF1688 PF07958.6 KKK14583.1 - 4.7e-166 552.4 0.0 5.3e-166 552.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) UPRTase PF14681.1 KKK14584.1 - 5.7e-66 221.6 0.0 7e-66 221.3 0.0 1.1 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 KKK14584.1 - 6.8e-05 22.5 0.0 9.2e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain MreB_Mbl PF06723.8 KKK14585.1 - 0.054 12.0 0.0 0.11 11.0 0.0 1.4 2 0 0 2 2 2 0 MreB/Mbl protein HSP70 PF00012.15 KKK14585.1 - 0.07 11.0 0.0 0.12 10.1 0.0 1.4 1 1 0 1 1 1 0 Hsp70 protein Fungal_trans PF04082.13 KKK14586.1 - 8.3e-09 34.6 0.0 2.1e-07 30.1 0.0 2.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK14586.1 - 4.9e-07 29.5 8.4 9.7e-07 28.5 5.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 KKK14587.1 - 1.4e-29 102.9 39.1 1.4e-29 102.9 27.1 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily SWIRM PF04433.12 KKK14591.1 - 4.6e-17 61.9 0.0 1.5e-16 60.2 0.0 1.9 2 0 0 2 2 2 1 SWIRM domain ZZ PF00569.12 KKK14591.1 - 7.1e-12 44.6 6.0 1.1e-11 44.0 4.2 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-binding PF00249.26 KKK14591.1 - 3.1e-08 33.5 0.0 7.5e-08 32.3 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Pkinase PF00069.20 KKK14592.1 - 2.1e-71 240.1 0.0 2.7e-71 239.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK14592.1 - 1e-32 113.2 0.0 1.4e-32 112.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 KKK14592.1 - 2.5e-08 34.2 1.1 2.5e-08 34.2 0.8 2.3 2 0 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.1 KKK14592.1 - 0.00076 18.5 0.0 0.0014 17.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like ECH PF00378.15 KKK14593.1 - 7.1e-49 166.1 0.1 9.2e-49 165.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family DUF1838 PF08894.6 KKK14593.1 - 0.023 13.9 0.0 0.058 12.6 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1838) Mannitol_dh_C PF08125.8 KKK14595.1 - 1.7e-48 164.9 0.0 2.4e-48 164.4 0.0 1.2 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.18 KKK14595.1 - 1.1e-12 48.2 1.2 4.4e-12 46.1 0.0 2.3 3 0 0 3 3 3 1 Mannitol dehydrogenase Rossmann domain Mit_ribos_Mrp51 PF11709.3 KKK14596.1 - 3.7e-98 328.6 0.2 5.5e-98 328.0 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit Epimerase PF01370.16 KKK14596.1 - 1.4e-16 60.6 0.0 2.2e-16 60.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KKK14596.1 - 6.4e-11 41.4 0.0 9.7e-11 40.8 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 KKK14596.1 - 1.1e-07 31.0 0.0 2.5e-07 29.8 0.0 1.6 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 KKK14596.1 - 1.5e-07 31.5 0.0 3.3e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 KKK14596.1 - 2.7e-05 24.1 0.0 7.6e-05 22.6 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KKK14596.1 - 0.014 15.0 0.0 0.027 14.1 0.0 1.4 1 0 0 1 1 1 0 KR domain UPF0184 PF03670.8 KKK14596.1 - 0.034 14.3 0.6 0.081 13.1 0.4 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0184) Ribosomal_S17e PF00833.13 KKK14597.1 - 2e-58 195.4 1.1 2.3e-58 195.2 0.8 1.0 1 0 0 1 1 1 1 Ribosomal S17 Cryptochrome_C PF12546.3 KKK14597.1 - 0.041 14.5 0.1 0.057 14.1 0.1 1.3 1 0 0 1 1 1 0 Blue/Ultraviolet sensing protein C terminal RPAP2_Rtr1 PF04181.8 KKK14598.1 - 9.3e-19 67.3 0.0 1.6e-18 66.5 0.0 1.4 1 0 0 1 1 1 1 Rtr1/RPAP2 family A2M_N_2 PF07703.9 KKK14598.1 - 0.12 12.2 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Alpha-2-macroglobulin family N-terminal region GATA PF00320.22 KKK14609.1 - 4.9e-16 57.7 4.5 9.6e-16 56.8 3.1 1.5 1 0 0 1 1 1 1 GATA zinc finger PAS PF00989.19 KKK14609.1 - 3.7e-05 23.4 0.0 0.00037 20.2 0.0 2.4 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.1 KKK14609.1 - 5.7e-05 23.4 0.0 0.0002 21.6 0.0 1.9 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.5 KKK14609.1 - 0.0034 17.3 0.0 0.015 15.2 0.0 2.1 2 0 0 2 2 2 1 PAS fold Zn-ribbon_8 PF09723.5 KKK14609.1 - 0.1 12.5 0.3 0.25 11.3 0.2 1.6 1 0 0 1 1 1 0 Zinc ribbon domain GRAB PF10375.4 KKK14611.1 - 6.7e-09 35.0 0.2 1.4e-08 34.0 0.1 1.5 1 0 0 1 1 1 1 GRIP-related Arf-binding domain Tup_N PF08581.5 KKK14611.1 - 0.0012 18.9 2.4 0.0012 18.9 1.7 4.6 3 2 1 4 4 4 2 Tup N-terminal Filament PF00038.16 KKK14611.1 - 0.0013 18.2 44.5 0.12 11.8 15.1 3.2 1 1 2 3 3 3 2 Intermediate filament protein TMF_TATA_bd PF12325.3 KKK14611.1 - 0.0071 16.0 5.8 0.0071 16.0 4.0 4.2 1 1 4 5 5 5 1 TATA element modulatory factor 1 TATA binding GAS PF13851.1 KKK14611.1 - 0.0092 15.1 7.9 0.0092 15.1 5.5 3.8 1 1 2 3 3 2 1 Growth-arrest specific micro-tubule binding Reo_sigmaC PF04582.7 KKK14611.1 - 0.053 12.7 10.5 0.24 10.5 2.0 2.6 2 1 0 2 2 2 0 Reovirus sigma C capsid protein HALZ PF02183.13 KKK14611.1 - 0.087 12.5 0.3 0.087 12.5 0.2 4.8 4 1 0 4 4 4 0 Homeobox associated leucine zipper DUF3584 PF12128.3 KKK14611.1 - 0.13 9.5 45.0 0.44 7.8 31.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) Spc7 PF08317.6 KKK14611.1 - 0.3 9.7 40.1 0.23 10.1 11.1 2.9 1 1 0 2 2 2 0 Spc7 kinetochore protein NPV_P10 PF05531.7 KKK14611.1 - 0.61 10.3 14.1 1.2 9.3 0.1 4.5 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein ApoO PF09769.4 KKK14611.1 - 1 9.0 12.7 1.4 8.6 1.1 3.6 1 1 2 3 3 3 0 Apolipoprotein O Phage_GP20 PF06810.6 KKK14611.1 - 1.9 7.9 46.1 0.016 14.6 3.4 4.7 2 1 3 5 5 5 0 Phage minor structural protein GP20 DUF4250 PF14056.1 KKK14611.1 - 3.6 7.3 6.4 0.56 9.9 0.3 2.8 3 1 0 3 3 2 0 Domain of unknown function (DUF4250) DUF1664 PF07889.7 KKK14611.1 - 5.1 6.9 23.9 4 7.2 0.3 4.0 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) RPW8 PF05659.6 KKK14611.1 - 8.8 5.8 13.1 0.48 9.9 0.4 3.1 2 1 1 3 3 3 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 IncA PF04156.9 KKK14611.1 - 9.5 5.7 51.9 19 4.7 3.4 3.9 1 1 2 3 3 2 0 IncA protein ATP-synt_ab PF00006.20 KKK14618.1 - 5.5e-62 209.0 0.0 7.8e-62 208.5 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 KKK14618.1 - 6.3e-16 58.8 0.0 1.2e-15 57.9 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 KKK14618.1 - 8.2e-09 35.5 0.2 2.2e-08 34.1 0.1 1.8 1 1 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 KKK14618.1 - 0.09 12.6 0.1 0.18 11.7 0.1 1.5 1 0 0 1 1 1 0 HAS barrel domain Usp PF00582.21 KKK14619.1 - 7.2e-17 61.8 3.9 1.4e-15 57.6 0.7 3.0 2 1 0 2 2 2 1 Universal stress protein family Rotamase_3 PF13616.1 KKK14637.1 - 1.4e-16 60.7 0.0 2.2e-16 60.1 0.0 1.4 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.16 KKK14637.1 - 1.9e-15 57.3 0.0 2.9e-15 56.7 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.1 KKK14637.1 - 7.2e-05 23.4 0.0 9.8e-05 22.9 0.0 1.2 1 1 0 1 1 1 1 PPIC-type PPIASE domain UAA PF08449.6 KKK14638.1 - 1.1e-72 244.5 11.2 2.4e-72 243.4 7.7 1.5 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 KKK14638.1 - 9e-07 28.9 9.1 9e-07 28.9 6.3 3.1 3 0 0 3 3 3 1 EamA-like transporter family Nuc_sug_transp PF04142.10 KKK14638.1 - 1.3e-06 27.6 3.0 0.011 14.7 0.0 2.4 2 0 0 2 2 2 2 Nucleotide-sugar transporter TPT PF03151.11 KKK14638.1 - 0.0093 15.6 9.5 0.0093 15.6 6.6 2.7 2 2 0 2 2 2 1 Triose-phosphate Transporter family EmrE PF13536.1 KKK14638.1 - 0.062 13.5 25.1 0.045 13.9 5.4 3.1 3 2 0 3 3 3 0 Multidrug resistance efflux transporter Sen15 PF09631.5 KKK14639.1 - 1.1e-17 64.0 0.0 6.8e-16 58.3 0.0 2.1 1 1 0 1 1 1 1 Sen15 protein tRNA_int_end_N2 PF12928.2 KKK14639.1 - 0.12 11.8 0.0 0.36 10.3 0.0 1.7 2 0 0 2 2 2 0 tRNA-splicing endonuclease subunit sen54 N-term PH PF00169.24 KKK14640.1 - 4.9e-08 33.1 0.0 1.8e-07 31.3 0.0 2.1 1 0 0 1 1 1 1 PH domain GRAM PF02893.15 KKK14640.1 - 0.00021 20.7 0.0 0.00051 19.5 0.0 1.6 1 0 0 1 1 1 1 GRAM domain PH_11 PF15413.1 KKK14640.1 - 0.0099 16.1 3.8 5.6 7.2 0.0 3.6 2 1 0 2 2 2 2 Pleckstrin homology domain JmjN PF02375.12 KKK14640.1 - 0.068 12.7 0.0 0.19 11.3 0.0 1.8 1 0 0 1 1 1 0 jmjN domain Kri1_C PF12936.2 KKK14641.1 - 4.9e-31 106.5 0.6 4.9e-31 106.5 0.4 3.6 2 1 1 3 3 3 1 KRI1-like family C-terminal Kri1 PF05178.7 KKK14641.1 - 1.3e-27 95.9 16.7 1.3e-27 95.9 11.6 4.3 4 1 1 5 5 5 1 KRI1-like family CRISPR_Cse2 PF09485.5 KKK14641.1 - 0.072 13.1 4.3 0.058 13.4 1.4 2.0 2 0 0 2 2 2 0 CRISPR-associated protein Cse2 (CRISPR_cse2) Mito_carr PF00153.22 KKK14642.1 - 3.8e-67 222.0 5.8 1.2e-23 82.5 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Aldo_ket_red PF00248.16 KKK14693.1 - 5.7e-44 150.0 0.0 1.2e-39 135.8 0.0 2.1 1 1 1 2 2 2 2 Aldo/keto reductase family zf-H2C2_2 PF13465.1 KKK14694.1 - 5.5e-07 29.5 8.9 1.2e-06 28.5 0.3 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 KKK14694.1 - 2.4e-05 24.3 9.4 0.00031 20.8 0.2 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KKK14694.1 - 3.1e-05 24.0 0.3 3.1e-05 24.0 0.2 3.8 3 1 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 KKK14694.1 - 0.018 14.9 0.3 4.9 7.1 0.0 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KKK14694.1 - 0.084 13.0 4.7 1.2 9.3 0.3 3.7 4 1 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KKK14694.1 - 0.17 12.1 1.2 8.5 6.7 0.0 3.2 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 KKK14695.1 - 6.2e-08 32.4 10.4 1.1e-05 25.3 1.9 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KKK14695.1 - 1.6e-07 31.2 9.5 5.8e-06 26.3 1.7 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KKK14695.1 - 6.2e-06 26.2 2.3 6.2e-06 26.2 1.6 3.8 4 0 0 4 4 4 1 Zinc-finger double domain zf-met PF12874.2 KKK14695.1 - 0.00014 21.9 8.7 0.00057 19.9 0.3 2.6 2 0 0 2 2 2 1 Zinc-finger of C2H2 type DUF2225 PF09986.4 KKK14695.1 - 0.00099 18.6 0.1 0.0016 17.9 0.1 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2225) zf-C2H2_jaz PF12171.3 KKK14695.1 - 0.0051 16.9 0.9 0.0051 16.9 0.6 2.0 2 0 0 2 2 1 1 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.7 KKK14695.1 - 0.0061 16.6 6.4 0.012 15.7 4.5 1.5 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding DUF1178 PF06676.6 KKK14695.1 - 0.04 14.1 1.3 0.053 13.7 0.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1178) GnHR_trans PF12369.3 KKK14695.1 - 0.059 13.8 0.4 0.17 12.3 0.3 1.7 1 0 0 1 1 1 0 Gonadotropin hormone receptor transmembrane region PRP21_like_P PF12230.3 KKK14695.1 - 0.071 12.6 0.7 0.095 12.1 0.5 1.2 1 0 0 1 1 1 0 Pre-mRNA splicing factor PRP21 like protein zf-C2H2_2 PF12756.2 KKK14695.1 - 0.085 12.9 1.9 0.14 12.3 1.3 1.3 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-BED PF02892.10 KKK14695.1 - 0.29 10.9 6.4 0.61 9.8 4.4 1.5 1 0 0 1 1 1 0 BED zinc finger zf-C2H2_6 PF13912.1 KKK14695.1 - 0.48 10.3 4.0 2.1 8.3 0.8 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger DUF533 PF04391.7 KKK14696.1 - 0.069 12.5 3.3 0.57 9.5 0.1 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF533) Prp31_C PF09785.4 KKK14698.1 - 4.1e-46 156.4 0.7 8.7e-46 155.3 0.5 1.6 1 0 0 1 1 1 1 Prp31 C terminal domain Nop PF01798.13 KKK14698.1 - 4.5e-37 126.6 0.0 7.4e-37 125.9 0.0 1.3 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 KKK14698.1 - 8.5e-13 47.9 0.1 1.7e-12 46.9 0.1 1.5 1 0 0 1 1 1 1 NOSIC (NUC001) domain TPR_14 PF13428.1 KKK14699.1 - 7.5e-23 78.9 12.8 0.002 18.5 0.0 11.5 6 2 6 12 12 12 4 Tetratricopeptide repeat HAT PF02184.11 KKK14699.1 - 4.8e-21 74.1 76.4 1.4e-13 50.2 4.2 12.7 13 0 0 13 13 13 6 HAT (Half-A-TPR) repeat TPR_16 PF13432.1 KKK14699.1 - 4e-17 62.3 10.3 0.0094 16.6 0.0 8.5 9 1 2 11 11 10 5 Tetratricopeptide repeat Suf PF05843.9 KKK14699.1 - 6.4e-15 55.6 19.8 3.3e-05 23.7 0.3 5.8 2 1 2 6 6 6 4 Suppressor of forked protein (Suf) TPR_19 PF14559.1 KKK14699.1 - 1e-13 51.4 0.1 0.00058 20.1 0.0 7.3 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_17 PF13431.1 KKK14699.1 - 7.2e-07 28.9 0.4 0.8 10.0 0.0 5.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.1 KKK14699.1 - 2.1e-06 27.3 1.6 0.85 9.3 0.0 6.2 6 1 1 7 7 7 2 TPR repeat TPR_2 PF07719.12 KKK14699.1 - 1.3e-05 24.7 14.8 0.12 12.3 0.0 7.9 10 0 0 10 10 9 1 Tetratricopeptide repeat TPR_12 PF13424.1 KKK14699.1 - 2e-05 24.4 13.8 0.055 13.4 0.0 7.5 9 0 0 9 9 8 1 Tetratricopeptide repeat U3_assoc_6 PF08640.6 KKK14699.1 - 0.0003 20.4 27.9 0.12 12.2 1.4 6.7 5 1 1 6 6 6 2 U3 small nucleolar RNA-associated protein 6 TPR_6 PF13174.1 KKK14699.1 - 0.023 15.1 15.4 3 8.5 0.0 7.1 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_7 PF13176.1 KKK14699.1 - 0.026 14.2 13.4 20 5.3 0.0 6.9 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_1 PF00515.23 KKK14699.1 - 0.081 12.5 1.7 5.3 6.8 0.0 4.3 5 0 0 5 5 4 0 Tetratricopeptide repeat NRDE-2 PF08424.5 KKK14699.1 - 0.14 10.9 0.1 0.14 10.9 0.1 6.6 3 3 1 5 5 5 0 NRDE-2, necessary for RNA interference Kelch_3 PF13415.1 KKK14700.1 - 2.5e-05 24.2 10.1 0.003 17.6 0.2 5.1 4 2 1 5 5 5 2 Galactose oxidase, central domain TMEM154 PF15102.1 KKK14700.1 - 0.00018 21.2 0.0 0.00054 19.6 0.0 1.8 1 0 0 1 1 1 1 TMEM154 protein family Kelch_5 PF13854.1 KKK14700.1 - 0.00024 20.9 2.3 1.3 9.0 0.1 3.8 3 0 0 3 3 3 2 Kelch motif Gly-zipper_Omp PF13488.1 KKK14700.1 - 0.035 13.7 0.4 0.035 13.7 0.3 2.0 2 0 0 2 2 2 0 Glycine zipper Rifin_STEVOR PF02009.11 KKK14700.1 - 0.044 13.4 0.0 0.074 12.6 0.0 1.3 1 0 0 1 1 1 0 Rifin/stevor family DUF2407_C PF13373.1 KKK14700.1 - 0.13 12.1 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 DUF2407 C-terminal domain SKG6 PF08693.5 KKK14700.1 - 0.21 10.9 0.7 0.5 9.7 0.5 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Podoplanin PF05808.6 KKK14700.1 - 0.97 8.9 11.1 0.48 9.9 5.7 1.8 1 1 1 2 2 2 0 Podoplanin Rick_17kDa_Anti PF05433.10 KKK14700.1 - 5.7 6.6 9.7 0.36 10.5 2.6 2.1 2 0 0 2 2 2 0 Glycine zipper 2TM domain adh_short PF00106.20 KKK14701.1 - 1.9e-20 73.4 3.0 7.2e-20 71.5 0.0 2.5 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 KKK14701.1 - 4.8e-17 62.5 0.0 1.1e-16 61.2 0.0 1.6 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KKK14701.1 - 4.6e-08 32.9 0.6 1.4e-07 31.3 0.0 2.0 2 0 0 2 2 2 1 KR domain DUF3843 PF12954.2 KKK14701.1 - 0.0075 15.3 0.0 0.01 14.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3843) ATP-cone PF03477.11 KKK14701.1 - 0.32 11.4 2.1 3.4 8.1 0.2 2.5 2 0 0 2 2 2 0 ATP cone domain Mito_fiss_reg PF05308.6 KKK14701.1 - 0.56 9.5 6.0 0.91 8.8 4.2 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator AdoHcyase PF05221.12 KKK14702.1 - 8.9e-137 454.3 0.0 1e-136 454.1 0.0 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.16 KKK14702.1 - 5.5e-84 279.9 1.3 8.6e-84 279.3 0.9 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.14 KKK14702.1 - 5.9e-06 25.5 0.1 1.3e-05 24.4 0.1 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.7 KKK14702.1 - 0.00045 19.6 0.2 0.00082 18.7 0.1 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain TrkA_N PF02254.13 KKK14702.1 - 0.001 19.0 0.1 0.0022 18.0 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain ELFV_dehydrog PF00208.16 KKK14702.1 - 0.0074 15.8 0.1 0.016 14.7 0.1 1.6 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase TMEM107 PF14995.1 KKK14702.1 - 0.048 13.7 0.0 0.083 13.0 0.0 1.3 1 0 0 1 1 1 0 Transmembrane protein DUF1349 PF07081.6 KKK14710.1 - 2.9e-18 65.8 0.0 1.2e-16 60.6 0.0 2.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1349) Peptidase_M24 PF00557.19 KKK14759.1 - 1.3e-30 106.4 0.0 7.3e-29 100.8 0.0 2.1 1 1 0 1 1 1 1 Metallopeptidase family M24 Med3 PF11593.3 KKK14759.1 - 0.022 14.0 0.1 0.03 13.5 0.0 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Glyco_transf_54 PF04666.8 KKK14760.1 - 4.7e-11 41.9 0.5 0.00011 21.1 0.0 2.9 3 0 0 3 3 3 2 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region Glucos_trans_II PF14264.1 KKK14760.1 - 0.0061 15.5 0.6 0.0061 15.5 0.4 1.6 2 0 0 2 2 2 1 Glucosyl transferase GtrII DUF4131 PF13567.1 KKK14760.1 - 4.6 6.6 6.3 4.7 6.5 1.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Pam17 PF08566.5 KKK14761.1 - 8.3e-71 237.2 0.0 8.3e-71 237.2 0.0 1.9 3 0 0 3 3 3 1 Mitochondrial import protein Pam17 Far-17a_AIG1 PF04750.9 KKK14761.1 - 5.6e-70 234.6 9.0 5.6e-70 234.6 6.3 1.9 2 0 0 2 2 2 1 FAR-17a/AIG1-like protein Med3 PF11593.3 KKK14761.1 - 5.6 6.0 12.3 8.6 5.4 8.5 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Fungal_trans_2 PF11951.3 KKK14762.1 - 1.8e-07 30.1 5.1 2.1e-07 29.8 0.2 2.3 2 1 1 3 3 3 2 Fungal specific transcription factor domain DUF3602 PF12223.3 KKK14763.1 - 3.4e-17 62.6 2.8 3.4e-17 62.6 1.9 3.3 1 1 2 3 3 3 2 Protein of unknown function (DUF3602) SUN PF03856.8 KKK14766.1 - 2.4e-81 272.7 13.8 5e-81 271.6 9.6 1.5 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) TT_ORF1 PF02956.9 KKK14766.1 - 0.93 7.8 11.5 1.4 7.2 8.0 1.2 1 0 0 1 1 1 0 TT viral orf 1 Dicty_REP PF05086.7 KKK14766.1 - 2.6 5.7 22.7 3.7 5.1 15.7 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein PAP1 PF08601.5 KKK14766.1 - 10 5.7 32.1 16 5.0 22.2 1.3 1 0 0 1 1 1 0 Transcription factor PAP1 Ist1 PF03398.9 KKK14767.1 - 5.3e-50 169.0 0.3 3.3e-24 85.1 1.0 2.1 2 0 0 2 2 2 2 Regulator of Vps4 activity in the MVB pathway TraI PF07057.6 KKK14767.1 - 0.036 14.0 0.3 0.73 9.8 0.1 2.2 2 0 0 2 2 2 0 DNA helicase TraI SAPS PF04499.10 KKK14767.1 - 0.13 10.9 0.0 0.16 10.5 0.0 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF1227 PF06777.6 KKK14768.1 - 1.1e-62 210.0 0.6 2.6e-62 208.8 0.4 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1227) DEAD_2 PF06733.10 KKK14768.1 - 3.4e-52 176.3 0.2 6.4e-52 175.4 0.2 1.5 1 0 0 1 1 1 1 DEAD_2 Helicase_C_2 PF13307.1 KKK14768.1 - 7e-45 152.9 0.0 1.7e-44 151.7 0.0 1.7 1 0 0 1 1 1 1 Helicase C-terminal domain SNF2_N PF00176.18 KKK14768.1 - 0.00043 19.1 0.0 0.0018 17.1 0.0 2.0 1 1 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.24 KKK14768.1 - 0.0015 18.0 0.0 0.17 11.3 0.0 2.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_11 PF13086.1 KKK14768.1 - 0.0016 18.0 0.0 0.004 16.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain ResIII PF04851.10 KKK14768.1 - 0.0046 16.8 0.0 0.019 14.8 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 KKK14768.1 - 0.028 14.5 0.9 1.5 8.9 0.0 2.9 3 0 0 3 3 3 0 AAA domain DUF2075 PF09848.4 KKK14768.1 - 0.077 11.9 0.0 4.2 6.2 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Stomoxyn PF11585.3 KKK14768.1 - 0.21 11.4 0.2 0.77 9.6 0.1 1.9 2 0 0 2 2 2 0 Insect antimicrobial peptide, stomoxyn RNA_pol_Rpb1_5 PF04998.12 KKK14769.1 - 4.5e-85 285.2 0.3 1e-84 284.0 0.2 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 KKK14769.1 - 1.1e-62 210.9 0.0 2.8e-62 209.5 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 KKK14769.1 - 7.7e-34 116.7 0.0 1.2e-32 112.8 0.0 2.9 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.7 KKK14769.1 - 2.5e-23 82.9 5.2 1.8e-16 60.3 0.0 2.9 2 1 1 3 3 3 2 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.12 KKK14769.1 - 6.7e-16 57.9 0.0 3.4e-15 55.7 0.0 2.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Gar1 PF04410.9 KKK14770.1 - 5.3e-47 159.1 0.1 5.3e-47 159.1 0.1 2.6 3 0 0 3 3 3 1 Gar1/Naf1 RNA binding region API5 PF05918.6 KKK14770.1 - 4.4 5.6 6.7 8.3 4.7 4.6 1.4 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) FA_desaturase PF00487.19 KKK14771.1 - 2.7e-11 43.3 26.3 2.7e-11 43.3 18.2 1.7 1 1 1 2 2 2 1 Fatty acid desaturase ABC_membrane PF00664.18 KKK14771.1 - 0.035 13.5 0.1 0.035 13.5 0.1 1.7 2 0 0 2 2 2 0 ABC transporter transmembrane region MFS_1 PF07690.11 KKK14772.1 - 9.1e-15 54.2 37.0 9.1e-15 54.2 25.6 2.3 1 1 1 2 2 2 1 Major Facilitator Superfamily LCM PF04072.9 KKK14773.1 - 1.3e-22 80.2 0.0 2.9e-22 79.1 0.0 1.6 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase C1_1 PF00130.17 KKK14773.1 - 0.035 13.8 1.1 0.074 12.7 0.7 1.5 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PRP3 PF08572.5 KKK14774.1 - 1.3e-72 243.7 5.6 2.5e-72 242.9 3.9 1.5 1 0 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.7 KKK14774.1 - 2.9e-40 136.9 0.1 6.5e-40 135.7 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) RNA_pol_Rpb5_C PF01191.14 KKK14782.1 - 5.6e-35 118.7 0.1 1.1e-34 117.8 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.9 KKK14782.1 - 9.7e-34 115.6 0.1 1.5e-33 115.0 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.7 KKK14782.1 - 0.039 13.7 0.0 0.093 12.5 0.0 1.6 2 0 0 2 2 2 0 Restriction endonuclease CENP-F_leu_zip PF10473.4 KKK14783.1 - 0.0044 16.8 43.2 0.3 10.9 4.5 4.3 2 1 2 4 4 4 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Reo_sigmaC PF04582.7 KKK14783.1 - 0.76 8.8 10.3 0.84 8.7 0.6 2.7 2 1 1 3 3 3 0 Reovirus sigma C capsid protein Baculo_p24 PF05073.7 KKK14783.1 - 1.4 8.4 18.3 0.077 12.5 2.1 2.9 3 0 0 3 3 3 0 Baculovirus P24 capsid protein APG6 PF04111.7 KKK14783.1 - 2.7 6.9 54.1 0.078 12.0 11.7 3.7 2 1 1 3 3 3 0 Autophagy protein Apg6 Ribosomal_S26e PF01283.14 KKK14811.1 - 1.7e-51 173.2 6.8 1.9e-51 173.0 4.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e Fer4_7 PF12838.2 KKK14811.1 - 0.024 14.9 1.0 0.59 10.5 0.4 2.2 2 0 0 2 2 2 0 4Fe-4S dicluster domain Zn_ribbon_2 PF12674.2 KKK14811.1 - 0.064 13.6 0.2 9.7 6.6 0.0 2.2 1 1 1 2 2 2 0 Putative zinc ribbon domain DUF1918 PF08940.6 KKK14811.1 - 0.13 11.5 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1918) CBS PF00571.23 KKK14812.1 - 2.8e-40 135.8 8.6 5.2e-10 38.9 0.0 4.7 5 0 0 5 5 5 4 CBS domain PB1 PF00564.19 KKK14812.1 - 6e-07 29.0 0.2 1.8e-06 27.5 0.0 2.0 2 1 0 2 2 2 1 PB1 domain HEAT_EZ PF13513.1 KKK14813.1 - 7.9e-20 70.7 19.7 1.3e-08 35.0 0.1 10.4 8 3 3 11 11 11 3 HEAT-like repeat HEAT PF02985.17 KKK14813.1 - 9.5e-20 68.8 11.2 0.00053 19.8 0.0 12.1 12 0 0 12 12 12 4 HEAT repeat HEAT_2 PF13646.1 KKK14813.1 - 7.8e-19 67.7 13.3 9.1e-07 29.0 0.2 8.7 6 2 2 8 8 8 3 HEAT repeats Vac14_Fab1_bd PF12755.2 KKK14813.1 - 8.2e-10 38.9 0.4 0.0086 16.4 0.0 6.5 3 2 3 6 6 6 2 Vacuolar 14 Fab1-binding region MMS19_C PF12460.3 KKK14813.1 - 1.5e-06 27.2 0.6 0.00028 19.7 0.1 4.1 3 1 1 4 4 4 1 RNAPII transcription regulator C-terminal CLASP_N PF12348.3 KKK14813.1 - 2.9e-05 23.5 0.1 0.064 12.6 0.1 5.7 7 1 1 8 8 8 1 CLASP N terminal Cnd1 PF12717.2 KKK14813.1 - 3.8e-05 23.6 0.3 0.82 9.4 0.0 4.8 4 1 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 RIX1 PF08167.7 KKK14813.1 - 4.4e-05 23.2 0.0 0.019 14.6 0.0 4.2 4 1 0 5 5 4 1 rRNA processing/ribosome biogenesis Proteasom_PSMB PF10508.4 KKK14813.1 - 0.00049 18.4 1.0 0.0017 16.7 0.1 2.3 2 0 0 2 2 2 1 Proteasome non-ATPase 26S subunit DUF3385 PF11865.3 KKK14813.1 - 0.00051 19.9 1.4 4.6 7.1 0.1 5.1 3 1 1 4 4 4 1 Domain of unknown function (DUF3385) Arm PF00514.18 KKK14813.1 - 0.00053 19.7 8.0 0.065 13.0 0.0 5.4 6 0 0 6 6 5 1 Armadillo/beta-catenin-like repeat IBN_N PF03810.14 KKK14813.1 - 0.0014 18.5 0.2 0.038 13.9 0.0 3.3 2 0 0 2 2 2 1 Importin-beta N-terminal domain TFCD_C PF12612.3 KKK14813.1 - 0.0043 16.5 0.2 2.6 7.4 0.0 3.6 2 1 0 2 2 2 1 Tubulin folding cofactor D C terminal Ipi1_N PF12333.3 KKK14813.1 - 0.0076 16.2 0.4 6.3 6.8 0.0 4.6 4 1 1 5 5 5 1 Rix1 complex component involved in 60S ribosome maturation Adaptin_N PF01602.15 KKK14813.1 - 0.038 12.3 6.4 0.015 13.6 0.4 3.0 3 2 0 3 3 3 0 Adaptin N terminal region V-ATPase_H_N PF03224.9 KKK14813.1 - 0.12 11.5 3.6 0.18 10.9 0.1 2.7 3 0 0 3 3 3 0 V-ATPase subunit H DUF2408 PF10303.4 KKK14814.1 - 1.2e-53 180.8 1.1 1.5e-31 109.2 0.3 4.9 2 2 3 5 5 5 4 Protein of unknown function (DUF2408) Baculo_PEP_C PF04513.7 KKK14814.1 - 0.04 13.7 1.5 0.1 12.3 0.4 2.2 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Snapin_Pallidin PF14712.1 KKK14814.1 - 0.18 12.1 4.3 0.46 10.8 0.3 3.2 4 0 0 4 4 4 0 Snapin/Pallidin Prefoldin_2 PF01920.15 KKK14814.1 - 0.37 10.5 3.2 15 5.4 0.0 3.1 3 1 1 4 4 4 0 Prefoldin subunit Ribosomal_60s PF00428.14 KKK14815.1 - 3.8e-25 88.1 10.9 5.1e-25 87.6 7.5 1.2 1 0 0 1 1 1 1 60s Acidic ribosomal protein Jun PF03957.8 KKK14815.1 - 0.0051 16.5 1.5 0.0062 16.2 1.0 1.0 1 0 0 1 1 1 1 Jun-like transcription factor Shadoo PF14999.1 KKK14815.1 - 0.51 10.1 7.6 0.83 9.5 5.3 1.2 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective LRR_6 PF13516.1 KKK14816.1 - 0.0001 21.9 0.3 0.59 10.3 0.0 4.1 4 0 0 4 4 4 2 Leucine Rich repeat LRR_4 PF12799.2 KKK14816.1 - 0.0029 17.1 2.4 0.4 10.3 0.3 3.7 2 1 1 3 3 3 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KKK14816.1 - 0.0077 16.1 1.5 2.5 8.4 0.0 4.4 4 0 0 4 4 4 1 Leucine Rich Repeat LRR_8 PF13855.1 KKK14816.1 - 0.025 14.3 2.4 3.3 7.5 1.1 3.7 2 1 2 4 4 4 0 Leucine rich repeat LRR_7 PF13504.1 KKK14816.1 - 0.091 13.0 1.4 7.5 7.2 0.0 4.4 5 0 0 5 5 5 0 Leucine rich repeat Gon7 PF08738.5 KKK14817.1 - 0.0032 17.4 2.3 0.26 11.2 0.3 2.4 2 0 0 2 2 2 2 Gon7 family Neur_chan_memb PF02932.11 KKK14817.1 - 0.087 12.6 1.0 0.11 12.3 0.7 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region zf-CCHC PF00098.18 KKK14817.1 - 0.51 10.3 3.4 0.24 11.3 0.9 1.6 1 1 0 1 1 1 0 Zinc knuckle DUF4600 PF15372.1 KKK14817.1 - 3.3 7.9 7.4 3 8.0 0.2 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4600) Cpn60_TCP1 PF00118.19 KKK14818.1 - 6.5e-141 470.2 3.8 7.5e-141 470.0 2.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Rep_fac_C PF08542.6 KKK14818.1 - 0.005 16.7 0.1 0.095 12.6 0.0 2.6 2 0 0 2 2 2 1 Replication factor C C-terminal domain Peptidase_C14 PF00656.17 KKK14819.1 - 9.1e-73 244.9 0.0 1.1e-72 244.7 0.0 1.0 1 0 0 1 1 1 1 Caspase domain Raptor_N PF14538.1 KKK14819.1 - 0.04 13.7 0.2 0.26 11.1 0.0 2.5 3 0 0 3 3 3 0 Raptor N-terminal CASPase like domain CNH PF00780.17 KKK14820.1 - 1.1e-82 277.6 0.0 5.9e-82 275.1 0.0 1.9 2 0 0 2 2 2 1 CNH domain PH_5 PF15405.1 KKK14820.1 - 5.7e-41 139.6 0.0 2e-40 137.8 0.0 2.0 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.15 KKK14820.1 - 1.2e-37 129.4 0.0 2.3e-37 128.6 0.0 1.5 1 0 0 1 1 1 1 RhoGEF domain DEP PF00610.16 KKK14820.1 - 7.6e-14 51.2 0.0 1.8e-13 50.0 0.0 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) ATP-synt_C PF00137.16 KKK14821.1 - 1.6e-25 88.7 30.8 3.7e-14 52.3 6.4 2.0 2 0 0 2 2 2 2 ATP synthase subunit C Pkinase PF00069.20 KKK14822.1 - 2.3e-05 23.7 0.0 3e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Arylesterase PF01731.15 KKK14842.1 - 9e-05 22.3 0.0 0.0014 18.5 0.0 2.7 3 0 0 3 3 3 1 Arylesterase DUF2457 PF10446.4 KKK14842.1 - 9.1 4.8 7.2 13 4.3 5.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) LETM1 PF07766.8 KKK14843.1 - 0.11 11.5 0.0 0.24 10.3 0.0 1.5 2 0 0 2 2 2 0 LETM1-like protein Bap31 PF05529.7 KKK14844.1 - 0.0047 16.4 0.2 0.91 8.9 0.0 2.2 2 0 0 2 2 2 2 B-cell receptor-associated protein 31-like Sel1 PF08238.7 KKK14845.1 - 6.5e-36 121.9 30.5 2.7e-06 27.8 0.3 7.7 7 0 0 7 7 7 7 Sel1 repeat Pkinase PF00069.20 KKK14847.1 - 2e-70 236.9 0.1 1.5e-69 234.0 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK14847.1 - 7.4e-45 153.0 0.0 1.1e-44 152.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KKK14847.1 - 2.5e-08 33.2 0.0 5.2e-08 32.2 0.0 1.5 2 0 0 2 2 2 1 Kinase-like POLO_box PF00659.13 KKK14847.1 - 3.1e-08 33.4 0.2 0.0018 18.2 0.0 2.7 2 0 0 2 2 2 2 POLO box duplicated region Kdo PF06293.9 KKK14847.1 - 0.1 11.6 0.0 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Chitin_synth_2 PF03142.10 KKK14848.1 - 1.1e-286 951.3 0.0 1.7e-286 950.7 0.0 1.2 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.1 KKK14848.1 - 4.5e-15 55.8 3.0 2.3e-14 53.5 2.1 2.3 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 KKK14848.1 - 6e-13 49.1 0.0 1.6e-10 41.1 0.0 2.7 2 1 0 2 2 2 2 Glycosyltransferase like family 2 Cyt-b5 PF00173.23 KKK14848.1 - 5.3e-10 38.9 0.2 4.9e-07 29.4 0.0 2.5 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glycos_transf_2 PF00535.21 KKK14848.1 - 1.9e-05 24.3 0.0 0.0026 17.4 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 KKK14848.1 - 9.7e-05 21.7 0.0 0.0009 18.5 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferase family 21 Myosin_head PF00063.16 KKK14849.1 - 3.7e-234 778.8 2.2 5.6e-234 778.2 1.5 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.8 KKK14849.1 - 2e-50 170.8 0.0 4.1e-50 169.8 0.0 1.6 1 0 0 1 1 1 1 Myosin tail OPA3 PF07047.7 KKK14849.1 - 1.5e-32 112.1 1.6 4.1e-32 110.7 1.1 1.7 1 0 0 1 1 1 1 Optic atrophy 3 protein (OPA3) SH3_1 PF00018.23 KKK14849.1 - 1.6e-12 46.5 0.1 2.9e-12 45.7 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KKK14849.1 - 1.2e-08 34.3 0.0 2.9e-08 33.0 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 KKK14849.1 - 1.1e-07 31.2 0.0 2.4e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain IQ PF00612.22 KKK14849.1 - 0.002 17.5 6.8 0.46 10.2 0.4 2.7 2 0 0 2 2 2 2 IQ calmodulin-binding motif AAA_22 PF13401.1 KKK14849.1 - 0.0043 17.2 0.0 0.015 15.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KKK14849.1 - 0.024 13.7 0.1 0.08 12.0 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin AAA_17 PF13207.1 KKK14849.1 - 0.029 15.1 0.0 0.089 13.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain Hpr_kinase_C PF07475.7 KKK14849.1 - 0.043 13.1 1.2 2.1 7.6 0.0 2.7 3 0 0 3 3 3 0 HPr Serine kinase C-terminal domain AAA_18 PF13238.1 KKK14849.1 - 0.059 13.6 0.0 0.16 12.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 KKK14849.1 - 0.094 12.3 0.0 0.43 10.2 0.0 2.0 2 0 0 2 2 2 0 NACHT domain Med11 PF10280.4 KKK14849.1 - 0.25 11.4 2.5 0.23 11.5 0.3 2.0 2 0 0 2 2 1 0 Mediator complex protein 2H-phosphodiest PF08975.5 KKK14864.1 - 0.073 12.8 0.1 0.22 11.2 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1868) Laminin_II PF06009.7 KKK14865.1 - 0.007 16.1 0.5 0.0085 15.8 0.3 1.2 1 0 0 1 1 1 1 Laminin Domain II CAF-1_p150 PF11600.3 KKK14865.1 - 0.01 15.2 10.6 0.012 14.9 7.4 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal MutS_IV PF05190.13 KKK14865.1 - 0.043 13.9 1.0 0.069 13.3 0.7 1.3 1 0 0 1 1 1 0 MutS family domain IV ATP-synt_B PF00430.13 KKK14865.1 - 0.19 11.5 7.9 0.29 10.9 5.5 1.2 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) Phage_1_1 PF08200.6 KKK14865.1 - 0.3 11.3 2.6 0.24 11.6 0.5 1.9 2 0 0 2 2 2 0 Bacteriophage 1.1 Protein FAD_binding_4 PF01565.18 KKK14866.1 - 2.1e-32 111.4 7.7 4.5e-32 110.4 5.1 1.8 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 KKK14866.1 - 1.1e-06 28.4 0.1 2.5e-06 27.2 0.1 1.6 1 0 0 1 1 1 1 Berberine and berberine like ADP_ribosyl_GH PF03747.9 KKK14867.1 - 9e-55 186.4 0.0 1.3e-54 185.9 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase MFS_1 PF07690.11 KKK14867.1 - 5.7e-31 107.5 56.4 1.6e-29 102.7 13.3 2.7 2 1 1 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.8 KKK14867.1 - 1.1e-16 60.2 13.6 2.1e-16 59.2 9.4 1.5 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF1206 PF06724.6 KKK14867.1 - 0.012 15.2 0.2 0.012 15.2 0.2 3.5 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1206) Ank_2 PF12796.2 KKK14868.1 - 5.1e-32 110.0 0.4 5.4e-15 55.5 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 KKK14868.1 - 7.2e-28 94.9 0.3 2.5e-07 30.1 0.0 4.7 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.1 KKK14868.1 - 1.3e-25 89.2 1.1 2.1e-10 40.7 0.0 3.6 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 KKK14868.1 - 5.8e-19 67.6 0.5 2.2e-09 37.2 0.0 3.4 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KKK14868.1 - 1.1e-18 65.4 0.3 0.00077 19.4 0.0 4.8 5 0 0 5 5 5 4 Ankyrin repeat bZIP_1 PF00170.16 KKK14868.1 - 3.9e-06 26.7 2.8 6.1e-06 26.0 2.0 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KKK14868.1 - 5e-05 23.0 0.7 7.7e-05 22.4 0.5 1.2 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 KKK14868.1 - 0.087 13.1 3.9 0.15 12.3 2.7 1.3 1 0 0 1 1 1 0 bZIP Maf transcription factor adh_short PF00106.20 KKK14869.1 - 5.4e-18 65.4 0.0 7.3e-18 65.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KKK14869.1 - 1.3e-08 34.6 0.0 1.8e-08 34.2 0.0 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KKK14869.1 - 2.6e-06 27.4 0.0 3.7e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KKK14869.1 - 0.02 14.3 0.1 0.051 12.9 0.1 1.8 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family FrhB_FdhB_C PF04432.8 KKK14870.1 - 0.047 13.1 0.0 0.077 12.3 0.0 1.3 1 0 0 1 1 1 0 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus YiaAB PF05360.9 KKK14870.1 - 0.083 12.4 0.0 0.23 11.0 0.0 1.7 1 0 0 1 1 1 0 yiaA/B two helix domain Fungal_trans PF04082.13 KKK14870.1 - 0.14 10.9 4.7 0.036 12.9 0.6 1.9 2 0 0 2 2 2 0 Fungal specific transcription factor domain Pyr_redox PF00070.22 KKK14871.1 - 2.3e-14 53.5 0.5 2.9e-08 34.0 0.1 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KKK14871.1 - 5.1e-14 52.6 2.2 7.6e-13 48.7 1.5 3.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KKK14871.1 - 3.6e-09 36.9 2.4 0.076 13.0 0.0 4.0 3 1 0 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KKK14871.1 - 2.6e-08 33.1 5.7 0.059 12.2 0.1 3.6 2 1 2 4 4 4 3 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KKK14871.1 - 2.5e-05 24.1 1.3 0.32 10.7 0.0 4.0 4 0 0 4 4 4 2 FAD-NAD(P)-binding TrkA_N PF02254.13 KKK14871.1 - 4.9e-05 23.3 0.9 0.2 11.6 0.0 3.3 4 0 0 4 4 4 2 TrkA-N domain K_oxygenase PF13434.1 KKK14871.1 - 0.00033 19.6 0.1 0.6 8.9 0.0 2.5 2 1 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.7 KKK14871.1 - 0.00043 19.3 1.0 0.16 10.8 0.0 2.9 4 0 0 4 4 4 2 Lycopene cyclase protein NAD_binding_7 PF13241.1 KKK14871.1 - 0.012 15.8 0.1 3.1 8.1 0.0 2.9 3 0 0 3 3 3 0 Putative NAD(P)-binding NAD_binding_8 PF13450.1 KKK14871.1 - 0.021 14.8 0.0 0.39 10.7 0.0 2.3 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KKK14871.1 - 0.09 11.8 2.5 5.8 5.9 0.1 2.6 3 0 0 3 3 3 0 Thi4 family DUF4353 PF14262.1 KKK14871.1 - 0.24 10.5 8.6 0.077 12.1 2.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4353) NmrA PF05368.8 KKK14872.1 - 3.6e-14 52.5 0.0 8.6e-14 51.3 0.0 1.6 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KKK14872.1 - 4e-06 26.9 0.0 5.2e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 KKK14872.1 - 0.0093 14.7 0.0 0.015 14.0 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 KKK14872.1 - 0.072 13.0 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 short chain dehydrogenase DUF829 PF05705.9 KKK14873.1 - 1.1e-57 195.5 0.0 1.2e-57 195.3 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) PapG_N PF03627.8 KKK14874.1 - 0.1 11.9 0.0 0.13 11.6 0.0 1.1 1 0 0 1 1 1 0 PapG carbohydrate binding domain VWA_2 PF13519.1 KKK14875.1 - 3.4e-05 24.0 0.0 9.9e-05 22.5 0.0 1.8 2 0 0 2 2 2 1 von Willebrand factor type A domain IBR PF01485.16 KKK14875.1 - 0.00022 21.0 9.5 0.00022 21.0 6.6 5.0 5 2 1 6 6 6 1 IBR domain VWA PF00092.23 KKK14875.1 - 0.00097 18.8 0.0 0.0018 18.0 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain Pec_lyase_C PF00544.14 KKK14876.1 - 2.4e-16 59.8 1.5 4.8e-16 58.8 1.1 1.5 1 0 0 1 1 1 1 Pectate lyase FAD_binding_4 PF01565.18 KKK14878.1 - 1.2e-31 108.9 6.9 2.1e-31 108.2 4.8 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KKK14878.1 - 6.1e-09 35.6 0.0 1.5e-08 34.3 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like GST_C PF00043.20 KKK14879.1 - 2.1e-11 43.6 0.0 3.3e-11 43.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KKK14879.1 - 8.3e-11 41.6 0.9 9.9e-11 41.3 0.2 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 KKK14879.1 - 5.7e-10 39.2 0.0 9.8e-10 38.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 KKK14879.1 - 2.5e-07 30.8 0.0 4.6e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 KKK14879.1 - 1e-06 29.1 0.2 1.6e-06 28.5 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 KKK14879.1 - 2e-06 27.6 0.0 4.5e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain SKG6 PF08693.5 KKK14880.1 - 0.0013 17.9 1.3 0.0027 16.9 0.9 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF1049 PF06305.6 KKK14880.1 - 0.0025 17.2 0.2 0.0059 16.0 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1049) Romo1 PF10247.4 KKK14880.1 - 0.029 14.5 0.2 0.062 13.5 0.1 1.5 1 0 0 1 1 1 0 Reactive mitochondrial oxygen species modulator 1 Lipase_GDSL PF00657.17 KKK14881.1 - 1.9e-20 73.7 0.0 2.4e-20 73.3 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 KKK14881.1 - 5.2e-19 69.0 0.0 6.6e-19 68.7 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family AP_endonuc_2 PF01261.19 KKK14881.1 - 0.089 12.0 0.0 1.1 8.5 0.0 2.0 1 1 1 2 2 2 0 Xylose isomerase-like TIM barrel 4HBT_3 PF13622.1 KKK14882.1 - 3e-55 187.7 0.7 3.4e-55 187.5 0.5 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.17 KKK14882.1 - 0.069 13.2 0.1 0.27 11.3 0.0 2.0 2 0 0 2 2 2 0 Thioesterase superfamily G-alpha PF00503.15 KKK14884.1 - 1.4e-134 448.6 1.0 1.7e-134 448.3 0.7 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 KKK14884.1 - 1.9e-15 56.5 1.6 2e-10 40.1 0.1 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family zf-CHC2 PF01807.15 KKK14884.1 - 8.1e-05 22.0 0.0 0.00037 19.9 0.0 2.0 2 0 0 2 2 2 1 CHC2 zinc finger Miro PF08477.8 KKK14884.1 - 0.0014 19.0 0.6 2.8 8.4 0.1 2.8 2 2 0 2 2 2 2 Miro-like protein Gtr1_RagA PF04670.7 KKK14884.1 - 0.0069 15.5 3.1 0.22 10.6 0.1 2.5 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region AAA_29 PF13555.1 KKK14884.1 - 0.0093 15.4 0.0 0.022 14.2 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain GTP_EFTU PF00009.22 KKK14884.1 - 0.021 14.2 0.0 1.1 8.6 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_23 PF13476.1 KKK14884.1 - 0.026 14.8 0.0 0.063 13.6 0.0 1.7 1 1 0 1 1 1 0 AAA domain MCM PF00493.18 KKK14884.1 - 0.082 11.6 0.0 0.14 10.9 0.0 1.4 1 0 0 1 1 1 0 MCM2/3/5 family MMR_HSR1 PF01926.18 KKK14884.1 - 0.094 12.6 0.0 15 5.6 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.13 KKK14884.1 - 0.12 11.8 0.0 0.26 10.7 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family DUF1771 PF08590.5 KKK14885.1 - 1.5e-25 88.9 8.2 1.5e-25 88.9 5.7 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) Smr PF01713.16 KKK14885.1 - 1.3e-05 25.2 0.4 3.1e-05 24.0 0.1 1.7 2 0 0 2 2 2 1 Smr domain Pilt PF15453.1 KKK14885.1 - 0.092 12.4 0.7 0.11 12.1 0.5 1.0 1 0 0 1 1 1 0 Protein incorporated later into Tight Junctions Connexin43 PF03508.8 KKK14885.1 - 0.24 10.6 0.4 0.24 10.6 0.3 2.0 3 0 0 3 3 3 0 Gap junction alpha-1 protein (Cx43) Glyco_transf_92 PF01697.22 KKK14885.1 - 0.25 10.6 1.1 0.88 8.8 0.1 1.9 2 0 0 2 2 2 0 Glycosyltransferase family 92 CBF PF03914.12 KKK14887.1 - 1.1e-46 158.2 2.0 6.1e-46 155.8 0.0 2.9 2 0 0 2 2 2 1 CBF/Mak21 family tRNA-synt_2b PF00587.20 KKK14888.1 - 2.3e-33 115.1 0.0 3.4e-33 114.6 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 KKK14888.1 - 1.2e-13 50.7 0.1 3.5e-13 49.2 0.0 1.8 2 0 0 2 2 2 1 Anticodon binding domain ADK_lid PF05191.9 KKK14888.1 - 0.045 13.4 0.1 0.094 12.3 0.1 1.5 1 0 0 1 1 1 0 Adenylate kinase, active site lid Bcl-2 PF00452.14 KKK14888.1 - 0.069 13.2 0.0 0.16 12.0 0.0 1.6 1 0 0 1 1 1 0 Apoptosis regulator proteins, Bcl-2 family GCV_T PF01571.16 KKK14889.1 - 2.8e-58 196.7 0.0 4.6e-58 196.0 0.0 1.4 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 KKK14889.1 - 9.3e-19 67.2 0.2 2e-18 66.1 0.1 1.6 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain POP1 PF06978.6 KKK14889.1 - 0.004 16.8 0.0 0.0061 16.2 0.0 1.2 1 0 0 1 1 1 1 Ribonucleases P/MRP protein subunit POP1 Aa_trans PF01490.13 KKK14890.1 - 3.4e-29 101.5 34.0 4.3e-29 101.2 23.6 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein ILVD_EDD PF00920.16 KKK14918.1 - 0.026 12.9 0.0 0.032 12.6 0.0 1.1 1 0 0 1 1 1 0 Dehydratase family DUF4610 PF15384.1 KKK14918.1 - 0.11 12.0 0.0 0.15 11.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4610) tRNA-synt_1c PF00749.16 KKK14919.1 - 4.1e-95 318.0 0.0 5.3e-95 317.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain CTDII PF01556.13 KKK14920.1 - 1.5e-22 79.2 0.2 1.6e-19 69.5 0.0 2.6 2 0 0 2 2 2 2 DnaJ C terminal domain DnaJ PF00226.26 KKK14920.1 - 3.3e-22 77.9 1.7 6e-22 77.1 1.2 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 KKK14920.1 - 1.2e-13 50.8 16.3 2.1e-13 50.0 11.3 1.4 1 0 0 1 1 1 1 DnaJ central domain zf-CHY PF05495.7 KKK14920.1 - 0.67 10.1 5.5 3 8.0 0.3 2.4 2 0 0 2 2 2 0 CHY zinc finger HypA PF01155.14 KKK14920.1 - 0.95 9.1 11.1 1.5 8.5 1.5 2.4 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family GCC2_GCC3 PF07699.8 KKK14920.1 - 5.6 6.6 14.1 9.4 5.9 1.5 2.6 2 0 0 2 2 2 0 GCC2 and GCC3 JAB PF01398.16 KKK14921.1 - 2.1e-27 95.1 0.0 3.8e-27 94.2 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 KKK14921.1 - 8.8e-07 28.4 0.0 1.8e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain MAP65_ASE1 PF03999.7 KKK14922.1 - 7.5e-70 236.2 12.6 7.5e-70 236.2 8.7 2.0 1 1 1 2 2 2 2 Microtubule associated protein (MAP65/ASE1 family) Baculo_PEP_C PF04513.7 KKK14922.1 - 0.071 12.9 2.9 0.7 9.7 1.4 3.0 5 0 0 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus LXG PF04740.7 KKK14922.1 - 1.2 8.8 9.5 0.5 10.1 3.1 2.8 4 0 0 4 4 4 0 LXG domain of WXG superfamily Fungal_trans PF04082.13 KKK14923.1 - 4.1e-19 68.4 5.1 6.5e-19 67.8 3.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.1 KKK14923.1 - 3.4e-07 30.2 15.2 0.0001 22.4 4.0 3.1 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 KKK14923.1 - 3.4e-05 23.8 13.3 0.004 17.3 3.6 3.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KKK14923.1 - 0.004 17.4 19.6 0.035 14.4 4.0 3.4 3 0 0 3 3 3 2 Zinc finger, C2H2 type RasGEF PF00617.14 KKK14924.1 - 1.3e-63 214.1 0.1 2.3e-63 213.3 0.0 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 KKK14924.1 - 1.2e-27 95.9 0.1 3.3e-27 94.6 0.1 1.8 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_1 PF00018.23 KKK14924.1 - 2.3e-16 58.9 0.1 4.6e-16 57.9 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KKK14924.1 - 3.8e-14 51.9 0.1 1.4e-13 50.1 0.1 2.0 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 KKK14924.1 - 3.6e-11 42.3 0.1 8.2e-11 41.2 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain WW PF00397.21 KKK14924.1 - 0.0018 18.1 0.0 0.0039 17.0 0.0 1.6 1 0 0 1 1 1 1 WW domain UPRTase PF14681.1 KKK14925.1 - 3.6e-71 238.6 0.0 4.1e-71 238.4 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 KKK14925.1 - 2.3e-06 27.3 0.0 5.3e-06 26.1 0.0 1.6 1 1 0 1 1 1 1 Phosphoribosyl transferase domain CRCB PF02537.10 KKK14926.1 - 1.9e-30 105.1 20.5 1.8e-18 66.5 5.7 3.6 3 1 1 4 4 4 3 CrcB-like protein RNA_pol_Rpc4 PF05132.9 KKK14929.1 - 2.4e-33 114.9 0.0 2.4e-33 114.9 0.0 4.2 2 2 2 4 4 4 1 RNA polymerase III RPC4 PBP1_TM PF14812.1 KKK14929.1 - 0.029 14.6 12.2 0.029 14.6 8.4 4.1 2 1 2 4 4 4 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF1524 PF07510.6 KKK14934.1 - 1.7e-15 57.0 0.0 2.1e-15 56.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1524) HNH_4 PF13395.1 KKK14934.1 - 0.017 14.7 0.2 0.044 13.4 0.2 1.7 1 1 0 1 1 1 0 HNH endonuclease MFS_1 PF07690.11 KKK14935.1 - 8.3e-41 139.8 45.6 8.3e-41 139.8 31.6 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KKK14935.1 - 0.00021 19.9 41.8 0.0034 16.0 29.0 2.6 1 1 0 1 1 1 1 Sugar (and other) transporter Sugar_tr PF00083.19 KKK14936.1 - 1.9e-111 372.8 24.6 2.2e-111 372.6 17.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KKK14936.1 - 3.3e-23 81.9 29.5 1.6e-22 79.6 17.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Abhydrolase_2 PF02230.11 KKK14937.1 - 1.9e-27 96.1 0.0 7.2e-19 68.0 0.0 2.1 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 KKK14937.1 - 2.7e-06 27.4 1.4 1e-05 25.5 1.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KKK14937.1 - 0.00011 22.0 0.0 0.00017 21.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family LIP PF03583.9 KKK14937.1 - 0.082 12.0 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 Secretory lipase Peptidase_S9 PF00326.16 KKK14937.1 - 0.13 11.4 0.0 1.7 7.8 0.0 2.4 3 0 0 3 3 3 0 Prolyl oligopeptidase family AA_permease PF00324.16 KKK14938.1 - 1.2e-114 383.3 47.0 1.3e-114 383.1 32.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KKK14938.1 - 1.6e-41 142.2 49.3 2.3e-41 141.7 34.2 1.3 1 0 0 1 1 1 1 Amino acid permease IMP_cyclohyd PF07826.6 KKK14939.1 - 0.17 11.2 0.1 1.2 8.4 0.0 2.0 1 1 1 2 2 2 0 IMP cyclohydrolase-like protein Redoxin PF08534.5 KKK14940.1 - 4.4e-38 130.1 0.0 4.9e-38 129.9 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 KKK14940.1 - 4.5e-13 48.9 0.0 5.8e-13 48.6 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family GPI2 PF06432.6 KKK14941.1 - 3.2e-126 420.4 1.3 3.8e-126 420.1 0.9 1.1 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase Glyco_hydro_18 PF00704.23 KKK14942.1 - 2.2e-50 172.0 0.9 1.5e-49 169.3 0.6 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.14 KKK14942.1 - 2.7e-06 27.2 21.5 5.7e-06 26.2 14.9 1.5 1 0 0 1 1 1 1 Chitin recognition protein Glyco_hydro_66 PF13199.1 KKK14942.1 - 0.027 12.9 0.0 0.043 12.2 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 66 Fumble PF03630.9 KKK14943.1 - 7e-139 462.4 4.2 8.4e-138 458.8 2.9 2.2 1 1 0 1 1 1 1 Fumble DUF2796 PF10986.3 KKK14943.1 - 0.0061 16.5 22.4 0.0097 15.8 15.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2796) Zip PF02535.17 KKK14943.1 - 0.025 13.5 4.7 0.035 13.1 3.3 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter CDC45 PF02724.9 KKK14943.1 - 0.068 11.1 3.9 0.1 10.6 2.7 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF2457 PF10446.4 KKK14943.1 - 0.12 11.0 14.2 0.18 10.5 9.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Gpi16 PF04113.9 KKK14943.1 - 0.18 9.8 0.0 0.26 9.2 0.0 1.1 1 0 0 1 1 1 0 Gpi16 subunit, GPI transamidase component SelP_N PF04592.9 KKK14943.1 - 0.32 10.3 15.0 0.53 9.6 10.4 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region HNH_2 PF13391.1 KKK14944.1 - 0.001 18.7 0.0 0.0034 17.1 0.0 1.8 2 0 0 2 2 2 1 HNH endonuclease Polysacc_deac_1 PF01522.16 KKK14945.1 - 5.8e-20 71.1 0.0 9.7e-20 70.4 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.4 KKK14945.1 - 0.021 14.2 0.0 0.034 13.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) SIR2 PF02146.12 KKK14945.1 - 0.099 12.3 0.1 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Sir2 family CoA_binding_2 PF13380.1 KKK14945.1 - 0.17 12.0 0.0 0.31 11.2 0.0 1.4 1 0 0 1 1 1 0 CoA binding domain DEAD PF00270.24 KKK14946.1 - 9e-44 148.9 0.0 4.5e-43 146.6 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KKK14946.1 - 3.3e-11 42.8 0.0 8.4e-11 41.5 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 KKK14946.1 - 8.1e-05 21.5 0.0 0.00011 21.0 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C_2 PF13307.1 KKK14946.1 - 0.073 13.0 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Helicase C-terminal domain ResIII PF04851.10 KKK14946.1 - 0.083 12.7 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit CMS1 PF14617.1 KKK14946.1 - 0.13 11.3 0.0 0.25 10.3 0.0 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Glyco_transf_29 PF00777.13 KKK14947.1 - 0.046 12.8 0.0 0.08 12.0 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 29 (sialyltransferase) Fringe PF02434.11 KKK14948.1 - 2.8e-09 36.5 0.1 6e-08 32.2 0.0 2.4 2 1 0 2 2 2 1 Fringe-like PAN_3 PF08277.7 KKK14948.1 - 0.098 12.2 0.3 0.19 11.3 0.2 1.4 1 0 0 1 1 1 0 PAN-like domain PAN_2 PF08276.6 KKK14948.1 - 0.13 12.1 1.0 0.26 11.1 0.7 1.4 1 0 0 1 1 1 0 PAN-like domain DFP PF04127.10 KKK14949.1 - 2.2e-15 56.7 0.0 2.2e-07 30.6 0.0 2.4 2 1 0 2 2 2 2 DNA / pantothenate metabolism flavoprotein FA_desaturase PF00487.19 KKK14950.1 - 8.3e-37 127.0 29.8 1.2e-36 126.4 20.7 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 KKK14950.1 - 5.9e-12 45.2 0.0 1.1e-11 44.3 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain SCO1-SenC PF02630.9 KKK14951.1 - 1.4e-58 197.3 0.0 1.9e-58 196.8 0.0 1.2 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.16 KKK14951.1 - 2e-05 24.2 0.1 4.3e-05 23.1 0.0 1.5 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.1 KKK14951.1 - 0.0012 18.9 0.0 0.002 18.1 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like MoaE PF02391.12 KKK14952.1 - 7.5e-30 103.1 0.1 9.6e-30 102.7 0.0 1.1 1 0 0 1 1 1 1 MoaE protein KH_dom-like PF14714.1 KKK14953.1 - 0.05 13.5 0.2 0.32 10.9 0.1 2.0 1 1 1 2 2 2 0 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal Fungal_trans PF04082.13 KKK14954.1 - 1.2e-20 73.4 0.0 2.4e-20 72.5 0.0 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Iso_dh PF00180.15 KKK14955.1 - 7.4e-88 294.8 0.0 8.3e-88 294.6 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase IU_nuc_hydro PF01156.14 KKK14955.1 - 0.056 12.6 0.1 0.099 11.8 0.1 1.4 1 0 0 1 1 1 0 Inosine-uridine preferring nucleoside hydrolase DUF1400 PF07176.6 KKK14955.1 - 0.071 13.0 0.0 0.59 10.0 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF1400) PdxA PF04166.7 KKK14955.1 - 0.093 11.9 0.1 0.18 11.0 0.0 1.5 2 0 0 2 2 2 0 Pyridoxal phosphate biosynthetic protein PdxA LrgA PF03788.9 KKK14956.1 - 0.071 12.8 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 LrgA family Acatn PF13000.2 KKK14958.1 - 4e-149 497.6 21.4 2.2e-76 257.5 5.3 3.1 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 Yae1_N PF09811.4 KKK14959.1 - 2.7e-12 45.9 0.2 5.8e-12 44.9 0.1 1.6 1 0 0 1 1 1 1 Essential protein Yae1, N terminal Abhydrolase_3 PF07859.8 KKK14961.1 - 9.9e-42 142.8 0.0 1.2e-41 142.6 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KKK14961.1 - 7.4e-09 35.1 0.0 2.6e-08 33.3 0.0 1.7 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 KKK14961.1 - 8.3e-07 29.1 0.1 3.3e-06 27.1 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 KKK14961.1 - 6.3e-06 25.6 0.0 0.05 12.8 0.0 2.3 2 0 0 2 2 2 2 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 KKK14961.1 - 6.6e-06 25.9 0.0 9.5e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 KKK14961.1 - 0.0014 18.0 0.0 0.0046 16.4 0.0 1.8 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) AXE1 PF05448.7 KKK14961.1 - 0.0032 15.9 0.0 1.4 7.3 0.0 2.1 2 0 0 2 2 2 2 Acetyl xylan esterase (AXE1) BAAT_C PF08840.6 KKK14961.1 - 0.015 15.0 0.0 0.025 14.2 0.0 1.4 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal COesterase PF00135.23 KKK14961.1 - 0.029 13.1 0.0 0.06 12.0 0.0 1.4 1 1 0 1 1 1 0 Carboxylesterase family Abhydrolase_2 PF02230.11 KKK14961.1 - 0.029 13.8 0.0 0.063 12.7 0.0 1.5 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase CENP-O PF09496.5 KKK14963.1 - 4.6e-27 94.0 0.0 9.4e-27 93.0 0.0 1.5 1 0 0 1 1 1 1 Cenp-O kinetochore centromere component Sfi1_C PF10638.4 KKK14963.1 - 0.089 13.2 0.2 0.21 12.0 0.1 1.6 1 0 0 1 1 1 0 Spindle body associated protein C-terminus APG6 PF04111.7 KKK14965.1 - 0.39 9.7 10.5 0.76 8.7 7.3 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 V_ATPase_I PF01496.14 KKK14965.1 - 2.2 6.0 2.7 2.9 5.6 1.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family AMP-binding PF00501.23 KKK14977.1 - 2.6e-77 259.9 0.0 3.1e-77 259.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KKK14977.1 - 7.5e-13 49.2 0.1 2.9e-12 47.3 0.0 2.2 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain HTH_DeoR PF08220.7 KKK14977.1 - 0.074 12.6 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain Patatin PF01734.17 KKK14979.1 - 1.6e-27 96.7 0.1 3.5e-27 95.6 0.1 1.5 1 0 0 1 1 1 1 Patatin-like phospholipase SHMT PF00464.14 KKK14980.1 - 4.9e-197 654.1 0.0 5.8e-197 653.8 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.16 KKK14980.1 - 0.0067 15.6 0.0 0.013 14.6 0.0 1.4 1 1 0 1 1 1 1 Beta-eliminating lyase p450 PF00067.17 KKK15010.1 - 2.7e-55 187.7 0.0 3.6e-55 187.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 EpuA PF11772.3 KKK15010.1 - 0.045 13.2 0.1 5.6 6.4 0.0 2.6 2 0 0 2 2 2 0 DNA-directed RNA polymerase subunit beta MARVEL PF01284.18 KKK15026.1 - 2.5e-09 37.0 7.5 3.6e-09 36.5 5.2 1.2 1 0 0 1 1 1 1 Membrane-associating domain SecG PF03840.9 KKK15026.1 - 0.011 15.4 0.2 0.94 9.2 0.0 3.2 3 0 0 3 3 3 0 Preprotein translocase SecG subunit Choline_transpo PF04515.7 KKK15026.1 - 0.066 11.9 5.1 0.13 10.9 3.6 1.5 1 1 0 1 1 1 0 Plasma-membrane choline transporter DUF4013 PF13197.1 KKK15026.1 - 0.3 10.4 8.6 0.22 10.8 0.1 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF4013) CAF1 PF04857.15 KKK15027.1 - 5.5e-63 212.7 0.0 7.4e-63 212.3 0.0 1.2 1 0 0 1 1 1 1 CAF1 family ribonuclease NDUF_B12 PF08122.7 KKK15028.1 - 8.5e-19 67.0 2.0 1.1e-18 66.6 1.4 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family TPR_11 PF13414.1 KKK15029.1 - 5e-10 38.8 6.3 1e-07 31.4 1.2 3.1 3 1 0 3 3 3 2 TPR repeat TPR_2 PF07719.12 KKK15029.1 - 1.8e-05 24.2 2.9 1.5 8.8 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 KKK15029.1 - 0.00044 19.7 3.4 3.3 7.4 0.1 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 KKK15029.1 - 0.00045 20.1 4.0 0.096 12.6 0.2 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.1 KKK15029.1 - 0.0024 17.7 2.3 0.037 13.8 0.2 3.1 1 1 1 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 KKK15029.1 - 0.0031 17.1 2.7 0.93 9.4 0.0 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat Apc3 PF12895.2 KKK15029.1 - 0.048 13.8 0.0 0.12 12.5 0.0 1.8 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 KKK15029.1 - 0.087 13.5 8.2 3.8 8.4 0.1 3.8 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 KKK15029.1 - 0.11 13.2 0.2 0.11 13.2 0.1 3.3 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.1 KKK15029.1 - 0.8 9.7 0.0 0.8 9.7 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 KKK15029.1 - 1.7 9.2 4.4 8.9 7.0 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Cu_amine_oxid PF01179.15 KKK15030.1 - 9.4e-167 554.9 0.0 1.3e-166 554.4 0.0 1.2 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.11 KKK15030.1 - 2.3e-22 78.9 0.7 3e-21 75.3 0.1 2.3 1 1 1 2 2 2 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.11 KKK15030.1 - 1.1e-13 51.0 0.0 2e-13 50.1 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Sugar_tr PF00083.19 KKK15031.1 - 7.5e-44 150.0 24.8 2.3e-43 148.4 17.2 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KKK15031.1 - 3.2e-19 68.8 33.1 3.2e-19 68.8 22.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Acetyltransf_10 PF13673.1 KKK15031.1 - 0.00023 21.2 0.3 0.00068 19.7 0.2 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KKK15031.1 - 0.0011 18.9 0.4 0.003 17.5 0.3 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KKK15031.1 - 0.11 12.6 0.0 0.31 11.2 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DAO PF01266.19 KKK15032.1 - 1.2e-23 83.6 1.5 5e-23 81.5 1.0 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KKK15032.1 - 5.8e-06 26.6 0.0 0.00016 22.0 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KKK15032.1 - 2.3e-05 24.3 0.1 5.2e-05 23.1 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.1 KKK15032.1 - 0.00021 21.4 0.0 0.00041 20.5 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding Pyr_redox_2 PF07992.9 KKK15032.1 - 0.00064 19.6 0.0 0.0073 16.2 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KKK15032.1 - 0.0011 17.9 0.1 0.0025 16.7 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain 3HCDH_N PF02737.13 KKK15032.1 - 0.0044 16.6 0.0 0.0073 15.9 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.11 KKK15032.1 - 0.0055 16.1 0.1 0.01 15.2 0.1 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA FAD_binding_3 PF01494.14 KKK15032.1 - 0.0078 15.3 0.0 0.013 14.6 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_10 PF13460.1 KKK15032.1 - 0.024 14.6 0.0 0.87 9.5 0.0 2.2 2 0 0 2 2 2 0 NADH(P)-binding UDPG_MGDP_dh_N PF03721.9 KKK15032.1 - 0.033 13.5 0.0 0.047 13.0 0.0 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain AlaDh_PNT_C PF01262.16 KKK15032.1 - 0.048 13.2 0.0 0.083 12.4 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.1 KKK15032.1 - 0.049 13.6 0.1 0.16 11.9 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KKK15032.1 - 0.086 11.6 0.1 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A NAD_Gly3P_dh_N PF01210.18 KKK15032.1 - 0.17 11.6 0.2 2.7 7.7 0.1 2.2 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Shikimate_DH PF01488.15 KKK15032.1 - 0.18 11.9 0.0 0.37 10.8 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.14 KKK15033.1 - 3.3e-10 39.5 0.0 0.00011 21.4 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain Trp_halogenase PF04820.9 KKK15033.1 - 2e-06 26.7 0.0 0.0034 16.0 0.0 2.8 3 0 0 3 3 3 2 Tryptophan halogenase DAO PF01266.19 KKK15033.1 - 7.9e-05 21.7 0.1 0.00031 19.7 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KKK15033.1 - 0.0001 22.2 0.0 0.00033 20.6 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 KKK15033.1 - 0.0027 17.4 0.1 0.0084 15.9 0.0 1.8 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 KKK15033.1 - 0.031 14.1 0.0 0.049 13.5 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KKK15033.1 - 0.046 12.7 0.0 0.076 12.0 0.0 1.3 1 0 0 1 1 1 0 Thi4 family FAD_binding_2 PF00890.19 KKK15033.1 - 0.048 12.4 0.0 0.082 11.7 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain Pec_lyase_C PF00544.14 KKK15034.1 - 6.8e-48 162.7 7.4 9.8e-48 162.2 5.1 1.2 1 0 0 1 1 1 1 Pectate lyase Beta_helix PF13229.1 KKK15034.1 - 1e-06 28.6 8.2 3e-06 27.0 5.6 1.8 1 1 0 1 1 1 1 Right handed beta helix region Glyco_hydro_18 PF00704.23 KKK15035.1 - 3e-13 49.9 0.0 5e-13 49.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Tub_2 PF04525.7 KKK15036.1 - 2.6e-07 30.2 0.0 1.8e-06 27.5 0.0 2.0 1 1 0 1 1 1 1 Tubby C 2 Lipase_GDSL PF00657.17 KKK15037.1 - 1e-17 64.7 0.3 1.3e-17 64.4 0.2 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase AMP-binding PF00501.23 KKK15038.1 - 1.3e-72 244.4 0.0 1.7e-72 244.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KKK15038.1 - 5.4e-13 49.6 0.2 1.8e-12 48.0 0.1 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain WD40 PF00400.27 KKK15039.1 - 4.5e-34 115.0 0.9 3.9e-08 32.8 0.0 7.8 8 0 0 8 8 8 6 WD domain, G-beta repeat Apc4_WD40 PF12894.2 KKK15039.1 - 0.0059 16.0 0.0 5.4 6.6 0.0 3.1 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.3 KKK15039.1 - 0.0084 14.2 0.0 0.12 10.4 0.0 2.2 2 0 0 2 2 2 2 Nucleoporin Nup120/160 Reo_sigmaC PF04582.7 KKK15053.1 - 0.43 9.7 6.6 4.7 6.2 4.6 2.2 1 1 0 1 1 1 0 Reovirus sigma C capsid protein DUF4446 PF14584.1 KKK15053.1 - 4.9 6.9 7.9 1 9.1 2.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) RibD_C PF01872.12 KKK15054.1 - 3e-34 118.3 0.0 3.6e-34 118.1 0.0 1.1 1 0 0 1 1 1 1 RibD C-terminal domain adh_short PF00106.20 KKK15055.1 - 3.2e-25 88.9 2.8 1.8e-24 86.5 1.3 2.2 1 1 1 2 2 2 1 short chain dehydrogenase KR PF08659.5 KKK15055.1 - 2.4e-09 37.1 3.4 3.5e-07 30.0 2.2 2.9 1 1 1 2 2 2 1 KR domain adh_short_C2 PF13561.1 KKK15055.1 - 2.8e-08 33.8 0.0 4.5e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 KKK15055.1 - 8.9e-05 22.5 0.3 0.00063 19.8 0.1 2.3 1 1 0 2 2 2 1 NADH(P)-binding B12-binding PF02310.14 KKK15055.1 - 0.037 13.9 0.1 1.5 8.7 0.0 2.4 2 0 0 2 2 2 0 B12 binding domain UPF0146 PF03686.8 KKK15055.1 - 0.037 13.8 0.0 0.066 13.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0146) PhnI PF05861.7 KKK15055.1 - 0.085 11.3 0.0 0.12 10.8 0.0 1.2 1 0 0 1 1 1 0 Bacterial phosphonate metabolism protein (PhnI) Zn_clus PF00172.13 KKK15058.1 - 6.6e-11 41.9 11.8 1.7e-10 40.6 8.2 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KKK15058.1 - 0.042 12.7 0.3 6.3 5.5 0.0 2.4 1 1 1 2 2 2 0 Fungal specific transcription factor domain RRN7 PF11781.3 KKK15058.1 - 0.069 12.6 3.9 0.18 11.3 2.7 1.6 1 0 0 1 1 1 0 RNA polymerase I-specific transcription initiation factor Rrn7 WD40 PF00400.27 KKK15069.1 - 7.6e-33 111.2 17.1 9.7e-13 47.4 0.5 6.9 7 1 1 8 8 8 5 WD domain, G-beta repeat eIF2A PF08662.6 KKK15069.1 - 1.4e-06 28.1 0.0 0.0077 15.9 0.0 2.7 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Lactonase PF10282.4 KKK15069.1 - 0.00012 21.3 0.0 0.0032 16.6 0.0 2.5 1 1 2 3 3 3 2 Lactonase, 7-bladed beta-propeller PQQ_2 PF13360.1 KKK15069.1 - 0.0015 18.0 1.2 0.0085 15.5 0.4 2.3 1 1 2 3 3 3 1 PQQ-like domain Nup160 PF11715.3 KKK15069.1 - 0.002 16.3 0.0 0.011 13.9 0.0 2.0 2 0 0 2 2 2 1 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 KKK15069.1 - 0.002 16.5 0.0 0.0056 15.0 0.0 1.6 1 1 0 1 1 1 1 Cytochrome D1 heme domain Nbas_N PF15492.1 KKK15069.1 - 0.0035 16.4 0.4 1 8.4 0.0 3.6 2 2 2 4 4 4 1 Neuroblastoma-amplified sequence, N terminal Coatomer_WDAD PF04053.9 KKK15069.1 - 0.15 10.8 0.0 0.2 10.4 0.0 1.2 1 0 0 1 1 1 0 Coatomer WD associated region Complex1_LYR PF05347.10 KKK15070.1 - 9.3e-06 25.3 2.3 2.4e-05 24.0 1.6 1.8 1 1 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KKK15070.1 - 0.012 15.8 1.3 0.021 15.0 0.9 1.6 1 1 0 1 1 1 0 Complex1_LYR-like Septin PF00735.13 KKK15071.1 - 1.3e-112 375.4 0.2 1.5e-112 375.2 0.1 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 KKK15071.1 - 1.7e-06 27.9 0.0 3.2e-06 27.0 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.11 KKK15071.1 - 8.6e-06 25.0 0.0 1.6e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 AIG1 family DUF258 PF03193.11 KKK15071.1 - 8.3e-05 21.8 0.0 0.00015 20.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 KKK15071.1 - 0.00021 20.8 0.2 0.018 14.5 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 KKK15071.1 - 0.00091 19.0 0.4 1.2 8.8 0.0 2.5 1 1 1 2 2 2 2 Dynamin family AAA_10 PF12846.2 KKK15071.1 - 0.0016 17.9 0.2 0.0016 17.9 0.1 1.4 1 1 0 1 1 1 1 AAA-like domain ABC_tran PF00005.22 KKK15071.1 - 0.015 15.5 0.3 0.02 15.1 0.2 1.6 1 1 0 1 1 1 0 ABC transporter FtsK_SpoIIIE PF01580.13 KKK15071.1 - 0.018 14.5 0.0 0.033 13.6 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family NB-ARC PF00931.17 KKK15071.1 - 0.02 13.7 0.0 0.035 12.9 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Gtr1_RagA PF04670.7 KKK15071.1 - 0.024 13.8 0.1 0.13 11.4 0.0 2.0 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region AAA_22 PF13401.1 KKK15071.1 - 0.024 14.7 0.0 0.06 13.4 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 KKK15071.1 - 0.028 14.3 0.0 0.063 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.1 KKK15071.1 - 0.051 13.8 0.0 0.09 13.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 KKK15071.1 - 0.063 13.7 0.0 0.18 12.3 0.0 1.8 2 0 0 2 2 2 0 Miro-like protein T2SE PF00437.15 KKK15071.1 - 0.084 11.7 0.0 0.17 10.7 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_7 PF12775.2 KKK15071.1 - 0.099 11.7 0.0 1.2 8.1 0.0 2.1 2 0 0 2 2 2 0 P-loop containing dynein motor region D3 AAA_29 PF13555.1 KKK15071.1 - 0.16 11.5 0.0 0.31 10.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Ribosomal_L32p PF01783.18 KKK15072.1 - 5.4e-14 52.1 7.4 7.4e-14 51.6 5.1 1.2 1 0 0 1 1 1 1 Ribosomal L32p protein family DZR PF12773.2 KKK15072.1 - 0.0043 16.8 0.8 0.0072 16.1 0.6 1.3 1 0 0 1 1 1 1 Double zinc ribbon Zn-ribbon_8 PF09723.5 KKK15072.1 - 0.18 11.7 2.8 7.1 6.6 0.1 2.2 1 1 1 2 2 2 0 Zinc ribbon domain zf-ribbon_3 PF13248.1 KKK15072.1 - 2.2 7.6 6.4 10 5.4 4.5 1.9 1 1 0 1 1 1 0 zinc-ribbon domain DUF2293 PF10056.4 KKK15073.1 - 3.1e-28 97.5 0.1 5.9e-28 96.6 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2293) DEAD PF00270.24 KKK15085.1 - 1.1e-44 151.8 0.0 1.6e-42 144.9 0.0 2.2 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 KKK15085.1 - 2.4e-22 78.5 0.0 5.6e-11 42.1 0.0 2.6 1 1 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.10 KKK15085.1 - 0.00065 19.5 0.0 0.0018 18.1 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2443 PF10398.4 KKK15085.1 - 0.021 14.6 0.2 0.053 13.3 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2443) POTRA_2 PF08479.6 KKK15085.1 - 0.073 12.7 0.0 0.17 11.5 0.0 1.6 1 0 0 1 1 1 0 POTRA domain, ShlB-type Helicase_C_2 PF13307.1 KKK15085.1 - 0.098 12.6 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Helicase C-terminal domain Desmo_N PF06771.6 KKK15085.1 - 0.11 12.3 0.2 7 6.6 0.1 2.6 2 0 0 2 2 2 0 Viral Desmoplakin N-terminus DNA_pol_B PF00136.16 KKK15086.1 - 1.5e-114 383.4 2.5 2.4e-114 382.6 1.7 1.3 1 0 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.5 KKK15086.1 - 2.9e-67 225.6 1.1 5e-67 224.9 0.8 1.4 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.14 KKK15086.1 - 4e-37 127.7 0.0 8.2e-37 126.7 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.3 KKK15086.1 - 1.6e-24 85.5 8.4 1.6e-24 85.5 5.8 2.6 2 0 0 2 2 2 1 DNA polymerase alpha subunit p180 N terminal LRR_4 PF12799.2 KKK15086.1 - 0.0088 15.6 3.3 3.6 7.3 0.2 4.6 2 1 1 3 3 3 1 Leucine Rich repeats (2 copies) Phos_pyr_kin PF08543.7 KKK15087.1 - 1.1e-83 280.2 0.3 1.5e-83 279.7 0.2 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.11 KKK15087.1 - 1.2e-53 181.9 0.1 1.7e-53 181.5 0.0 1.2 1 0 0 1 1 1 1 TENA/THI-4/PQQC family PfkB PF00294.19 KKK15087.1 - 9e-07 28.3 0.2 1.4e-06 27.6 0.1 1.3 1 0 0 1 1 1 1 pfkB family carbohydrate kinase HK PF02110.10 KKK15087.1 - 0.00019 20.6 0.8 0.0066 15.6 0.0 2.2 2 0 0 2 2 2 1 Hydroxyethylthiazole kinase family Carb_kinase PF01256.12 KKK15087.1 - 0.0011 18.2 2.3 0.0018 17.6 0.4 2.0 1 1 1 2 2 2 1 Carbohydrate kinase HsbA PF12296.3 KKK15088.1 - 4.3e-14 52.4 8.5 4.3e-12 45.9 1.0 2.8 2 1 1 3 3 3 2 Hydrophobic surface binding protein A CitG PF01874.11 KKK15088.1 - 0.012 14.7 0.5 0.014 14.5 0.4 1.2 1 0 0 1 1 1 0 ATP:dephospho-CoA triphosphoribosyl transferase Rad9 PF04139.8 KKK15089.1 - 1.1e-59 201.6 2.6 1.3e-59 201.3 1.8 1.1 1 0 0 1 1 1 1 Rad9 Rad1 PF02144.11 KKK15089.1 - 6.3e-06 25.1 2.7 9.6e-05 21.2 1.5 2.4 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 DUF2683 PF10884.3 KKK15089.1 - 0.017 15.0 0.0 1.7 8.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2683) RCC1 PF00415.13 KKK15090.1 - 1.7e-28 98.5 25.7 6.8e-08 32.5 0.1 7.8 5 3 0 5 5 5 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 KKK15090.1 - 8.7e-25 85.7 16.8 5.2e-08 32.2 0.1 5.5 5 0 0 5 5 5 5 Regulator of chromosome condensation (RCC1) repeat Sugar_tr PF00083.19 KKK15091.1 - 2.2e-20 72.6 21.5 1.1e-18 67.1 14.9 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter Prenyltrans PF00432.16 KKK15114.1 - 1.2e-42 143.0 35.1 1.7e-11 43.4 1.8 6.2 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 KKK15114.1 - 3.3e-26 91.9 0.0 1.9e-16 60.4 0.0 4.2 2 1 2 4 4 4 3 Prenyltransferase-like Prenyltrans_1 PF13243.1 KKK15114.1 - 0.0016 18.4 0.0 0.2 11.6 0.0 3.6 2 1 1 3 3 3 1 Prenyltransferase-like dsrm PF00035.20 KKK15115.1 - 0.00011 22.6 0.0 0.00021 21.8 0.0 1.4 1 0 0 1 1 1 1 Double-stranded RNA binding motif DND1_DSRM PF14709.1 KKK15115.1 - 0.0091 16.2 0.1 0.018 15.2 0.1 1.4 1 1 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 DUF607 PF04678.8 KKK15116.1 - 9.3e-45 152.7 0.0 9.3e-45 152.7 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function, DUF607 Hpt PF01627.18 KKK15117.1 - 2.9e-11 43.2 0.0 5.8e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 Hpt domain PTPLA PF04387.9 KKK15118.1 - 6.8e-54 181.7 1.8 1.1e-53 181.0 1.2 1.3 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA Adaptin_binding PF10199.4 KKK15119.1 - 7.1e-13 49.0 6.1 7.1e-13 49.0 4.2 2.7 2 2 0 2 2 2 1 Alpha and gamma adaptin binding protein p34 zf-C2H2 PF00096.21 KKK15124.1 - 1.3e-07 31.5 14.9 0.0014 18.8 1.3 3.2 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KKK15124.1 - 5.3e-07 29.6 25.8 1.1e-05 25.4 2.3 4.6 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 KKK15124.1 - 0.014 15.7 1.6 0.014 15.7 1.1 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KKK15124.1 - 2.8 8.1 5.2 0.41 10.8 0.2 2.2 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.1 KKK15125.1 - 0.097 13.0 0.9 0.097 13.0 0.6 2.5 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2_4 PF13894.1 KKK15125.1 - 0.13 12.7 0.8 0.13 12.7 0.6 4.3 4 0 0 4 4 4 0 C2H2-type zinc finger LSM PF01423.17 KKK15126.1 - 6.1e-13 48.1 0.1 9.3e-13 47.5 0.1 1.3 1 0 0 1 1 1 1 LSM domain NUC173 PF08161.7 KKK15127.1 - 1.3e-79 266.2 0.1 9.3e-79 263.3 0.0 2.4 3 0 0 3 3 3 1 NUC173 domain Stork_head PF10264.4 KKK15127.1 - 0.021 14.9 0.0 0.09 12.9 0.0 2.1 1 0 0 1 1 1 0 Winged helix Storkhead-box1 domain HEAT_2 PF13646.1 KKK15127.1 - 0.026 14.8 2.6 3.6 7.9 0.0 4.6 4 1 0 4 4 4 0 HEAT repeats HEAT PF02985.17 KKK15127.1 - 0.032 14.2 1.0 4.3 7.6 0.0 3.9 4 0 0 4 4 4 0 HEAT repeat Pkinase PF00069.20 KKK15131.1 - 3.5e-22 78.8 0.0 8.4e-22 77.5 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK15131.1 - 1.5e-08 34.0 0.0 9.5e-05 21.5 0.0 2.9 2 1 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.9 KKK15131.1 - 0.00043 19.4 0.0 0.00074 18.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KKK15131.1 - 0.0014 18.3 0.0 0.0026 17.5 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 KKK15131.1 - 0.0018 17.2 0.0 0.44 9.4 0.0 2.9 3 0 0 3 3 3 1 Kinase-like WaaY PF06176.6 KKK15131.1 - 0.042 13.0 0.0 0.063 12.4 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) DUF4537 PF15057.1 KKK15140.1 - 0.015 15.1 0.0 0.024 14.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4537) DUF1325 PF07039.6 KKK15140.1 - 0.057 13.0 0.2 0.23 11.0 0.0 2.0 2 0 0 2 2 2 0 SGF29 tudor-like domain Fis1_TPR_C PF14853.1 KKK15140.1 - 0.062 13.1 0.2 0.11 12.4 0.2 1.4 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat TUDOR PF00567.19 KKK15140.1 - 0.11 12.3 0.0 0.27 11.0 0.0 1.6 2 0 0 2 2 2 0 Tudor domain TP2 PF01254.13 KKK15140.1 - 5.7 7.2 12.5 0.17 12.2 4.2 1.7 2 0 0 2 2 2 0 Nuclear transition protein 2 PAP1 PF08601.5 KKK15141.1 - 1.8e-91 307.4 11.6 1.8e-91 307.4 8.1 2.4 2 1 0 2 2 2 1 Transcription factor PAP1 bZIP_1 PF00170.16 KKK15141.1 - 2.8e-09 36.8 7.5 5.9e-09 35.7 5.2 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KKK15141.1 - 0.027 14.2 12.9 0.17 11.7 8.9 2.2 1 1 0 1 1 1 0 Basic region leucine zipper Adeno_PIX PF03955.9 KKK15141.1 - 0.089 13.3 0.4 0.28 11.7 0.2 1.8 1 0 0 1 1 1 0 Adenovirus hexon-associated protein (IX) bZIP_Maf PF03131.12 KKK15141.1 - 0.19 12.0 11.4 0.15 12.3 6.0 2.2 2 0 0 2 2 2 0 bZIP Maf transcription factor IncA PF04156.9 KKK15141.1 - 0.49 9.9 2.8 1.3 8.5 1.6 1.9 2 0 0 2 2 2 0 IncA protein Zwint PF15556.1 KKK15141.1 - 0.6 9.3 8.0 2.1 7.5 5.3 2.0 1 1 1 2 2 2 0 ZW10 interactor XhlA PF10779.4 KKK15141.1 - 0.86 9.5 3.1 0.89 9.5 0.9 1.9 2 0 0 2 2 2 0 Haemolysin XhlA DUF2433 PF10360.4 KKK15142.1 - 2e-50 170.5 0.0 4e-50 169.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2433) DUF1793 PF08760.6 KKK15142.1 - 7.1e-50 169.2 0.0 1.3e-49 168.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) GBA2_N PF12215.3 KKK15142.1 - 0.00021 20.5 0.3 0.00068 18.8 0.2 1.9 2 1 0 2 2 2 1 beta-Glucocerebrosidase 2 N terminal Metallophos_2 PF12850.2 KKK15142.1 - 0.0094 15.7 0.0 0.022 14.5 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 KKK15142.1 - 0.011 15.0 0.0 0.023 14.0 0.0 1.5 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase DUF2360 PF10152.4 KKK15142.1 - 0.02 15.1 0.3 0.43 10.8 0.2 2.5 1 1 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) zf-RING_2 PF13639.1 KKK15184.1 - 2.9e-15 55.7 5.6 5e-15 55.0 3.9 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 KKK15184.1 - 5.9e-08 32.6 2.5 1.1e-07 31.8 1.7 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 KKK15184.1 - 1.2e-07 31.3 3.6 1.8e-07 30.6 2.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KKK15184.1 - 6.4e-07 29.2 5.3 1.1e-06 28.5 3.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KKK15184.1 - 3.5e-06 26.6 2.7 5.9e-06 25.9 1.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KKK15184.1 - 7.9e-06 25.4 2.2 1.3e-05 24.7 1.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KKK15184.1 - 0.0014 18.4 2.8 0.0029 17.3 1.9 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 KKK15184.1 - 0.0019 17.7 3.5 0.0034 16.9 2.5 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING-like PF08746.6 KKK15184.1 - 0.078 12.9 2.9 0.13 12.2 2.0 1.4 1 0 0 1 1 1 0 RING-like domain zf-C3HC4_4 PF15227.1 KKK15184.1 - 0.51 10.2 5.9 0.98 9.3 4.1 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.3 KKK15184.1 - 1.1 9.2 5.1 7.6 6.5 3.5 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain PHD PF00628.24 KKK15184.1 - 3.5 7.4 5.0 15 5.3 3.5 2.0 1 1 1 2 2 2 0 PHD-finger AMP-binding PF00501.23 KKK15185.1 - 8.2e-50 169.3 0.0 1.1e-49 168.9 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme ECH PF00378.15 KKK15185.1 - 3.6e-43 147.4 0.1 6e-43 146.7 0.0 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family HMGL-like PF00682.14 KKK15185.1 - 3.4e-40 138.1 0.0 5.3e-40 137.5 0.0 1.3 1 0 0 1 1 1 1 HMGL-like AMP-binding_C PF13193.1 KKK15185.1 - 6.6e-06 26.9 0.0 3.5e-05 24.6 0.0 2.2 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Fungal_trans PF04082.13 KKK15186.1 - 1e-25 90.1 2.2 1.8e-25 89.3 1.5 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK15186.1 - 2.2e-08 33.8 12.1 4.6e-08 32.8 8.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain LysM PF01476.15 KKK15187.1 - 3.4e-05 23.6 1.3 6.1e-05 22.8 0.0 2.1 3 0 0 3 3 3 1 LysM domain bZIP_1 PF00170.16 KKK15188.1 - 0.0007 19.5 1.2 0.0014 18.5 0.8 1.5 1 0 0 1 1 1 1 bZIP transcription factor DivIC PF04977.10 KKK15188.1 - 0.15 11.5 1.2 0.26 10.8 0.8 1.3 1 0 0 1 1 1 0 Septum formation initiator Epimerase PF01370.16 KKK15189.1 - 6e-16 58.5 0.0 1.8e-15 57.0 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KKK15189.1 - 4.6e-12 46.3 0.0 2.6e-11 43.8 0.0 1.9 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 KKK15189.1 - 4.9e-12 45.1 0.0 2e-11 43.1 0.0 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 KKK15189.1 - 5.1e-07 28.8 0.0 8.3e-06 24.9 0.0 2.2 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.20 KKK15189.1 - 1.7e-05 24.8 0.0 7.2e-05 22.7 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 KKK15189.1 - 5.9e-05 22.1 0.0 0.00012 21.0 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.8 KKK15189.1 - 0.0011 18.2 0.0 0.0078 15.4 0.0 2.0 2 0 0 2 2 2 1 NmrA-like family KR PF08659.5 KKK15189.1 - 0.026 14.1 0.1 0.32 10.6 0.0 2.2 1 1 0 1 1 1 0 KR domain Tautomerase_3 PF14832.1 KKK15190.1 - 2.8e-50 169.8 0.1 3.1e-50 169.7 0.0 1.0 1 0 0 1 1 1 1 Putative oxalocrotonate tautomerase enzyme AA_permease_2 PF13520.1 KKK15191.1 - 1.6e-55 188.3 42.0 2e-55 188.0 29.1 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KKK15191.1 - 5.4e-20 71.1 29.3 5.4e-20 71.1 20.3 2.1 2 0 0 2 2 2 1 Amino acid permease Glyco_hydro_76 PF03663.9 KKK15192.1 - 1.4e-124 416.2 24.6 8.3e-123 410.4 17.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 76 Peptidase_S10 PF00450.17 KKK15193.1 - 1.1e-92 311.4 0.1 1.4e-92 311.0 0.1 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase YXWGXW PF12779.2 KKK15193.1 - 0.21 11.5 0.7 0.46 10.4 0.5 1.6 1 0 0 1 1 1 0 YXWGXW repeat (2 copies) Glyco_hydro_92 PF07971.7 KKK15194.1 - 5.2e-174 579.5 0.0 6.9e-174 579.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Acyl-CoA_dh_1 PF00441.19 KKK15195.1 - 3.6e-29 101.7 2.7 5.4e-29 101.2 1.8 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 KKK15195.1 - 1.4e-19 70.7 0.1 6.8e-19 68.5 0.0 2.2 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 KKK15195.1 - 7.2e-19 67.0 1.2 1.2e-18 66.3 0.8 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 KKK15195.1 - 0.00033 20.9 1.3 0.00047 20.4 0.9 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain ATP-sulfurylase PF01747.12 KKK15195.1 - 0.12 11.7 0.1 0.56 9.4 0.0 2.0 2 0 0 2 2 2 0 ATP-sulfurylase HATPase_c PF02518.21 KKK15196.1 - 1.1e-24 86.2 0.0 8.9e-24 83.3 0.0 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_9 PF13426.1 KKK15196.1 - 5.3e-23 81.3 0.0 3.3e-15 56.3 0.0 2.4 2 0 0 2 2 2 2 PAS domain Response_reg PF00072.19 KKK15196.1 - 5.3e-23 81.1 0.0 1.2e-22 79.9 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 KKK15196.1 - 1.3e-18 66.7 0.1 2.9e-18 65.6 0.1 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS PF00989.19 KKK15196.1 - 1.3e-14 53.8 0.0 4.1e-09 36.2 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_4 PF08448.5 KKK15196.1 - 8.1e-10 38.7 0.0 9.8e-05 22.3 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_7 PF12860.2 KKK15196.1 - 0.096 12.7 0.0 0.25 11.3 0.0 1.7 1 1 0 1 1 1 0 PAS fold Alpha-amylase PF00128.19 KKK15197.1 - 7.7e-71 239.0 1.4 1e-70 238.6 1.0 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain CBM_20 PF00686.14 KKK15197.1 - 4.3e-34 115.9 0.1 1.1e-33 114.6 0.1 1.8 1 0 0 1 1 1 1 Starch binding domain DUF1966 PF09260.6 KKK15197.1 - 2.6e-33 113.9 0.2 5.7e-33 112.8 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) DUF3439 PF11921.3 KKK15197.1 - 9.6 5.9 17.4 29 4.4 12.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Cu-oxidase_3 PF07732.10 KKK15198.1 - 2.8e-41 139.9 3.5 2.8e-41 139.9 2.5 3.9 3 2 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.17 KKK15198.1 - 1.6e-39 135.3 0.8 1.8e-36 125.4 0.1 3.0 2 1 1 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 KKK15198.1 - 1.7e-39 134.4 15.8 3.7e-38 130.1 2.6 3.1 3 1 0 3 3 3 2 Multicopper oxidase Carboxyl_trans PF01039.17 KKK15199.1 - 6.8e-105 351.2 0.0 8.6e-105 350.9 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.12 KKK15200.1 - 2.2e-70 236.2 0.0 3.8e-70 235.4 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.14 KKK15200.1 - 8.2e-31 106.1 0.0 2.5e-30 104.6 0.0 1.9 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain CPSase_L_chain PF00289.17 KKK15200.1 - 2e-29 101.8 0.5 5.8e-18 64.9 0.0 2.9 3 0 0 3 3 3 2 Carbamoyl-phosphate synthase L chain, N-terminal domain ATP-grasp_4 PF13535.1 KKK15200.1 - 8.3e-16 58.2 0.0 1.5e-15 57.4 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl PF00364.17 KKK15200.1 - 2.1e-12 46.5 2.3 4.2e-12 45.5 1.6 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme ATPgrasp_Ter PF15632.1 KKK15200.1 - 8e-11 41.2 0.0 2.1e-10 39.8 0.0 1.5 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 KKK15200.1 - 2.8e-09 36.6 0.0 5.6e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 KKK15200.1 - 3.7e-09 36.1 0.0 8.1e-09 35.0 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 KKK15200.1 - 5.5e-05 22.7 0.0 0.00018 21.0 0.0 1.8 2 0 0 2 2 2 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.9 KKK15200.1 - 6.2e-05 22.9 0.0 0.0001 22.1 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.1 KKK15200.1 - 0.033 13.8 0.0 0.11 12.1 0.0 1.9 1 0 0 1 1 1 0 Biotin-lipoyl like GCV_H PF01597.14 KKK15200.1 - 0.081 12.6 0.1 0.25 11.0 0.1 1.8 1 0 0 1 1 1 0 Glycine cleavage H-protein ATPgrasp_YheCD PF14398.1 KKK15200.1 - 0.13 11.0 0.0 1.9 7.1 0.0 2.2 2 0 0 2 2 2 0 YheC/D like ATP-grasp DUF3182 PF11379.3 KKK15200.1 - 0.17 10.5 0.0 0.33 9.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3182) adh_short PF00106.20 KKK15201.1 - 1.3e-05 25.1 0.1 4.2e-05 23.5 0.0 1.8 1 1 1 2 2 2 1 short chain dehydrogenase Zn_clus PF00172.13 KKK15202.1 - 3.1e-08 33.3 12.1 5.1e-08 32.6 8.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KKK15202.1 - 0.0013 17.3 0.1 0.28 9.7 0.0 2.6 2 1 0 2 2 2 2 Fungal specific transcription factor domain PHD PF00628.24 KKK15203.1 - 1.3e-08 34.4 9.0 2.5e-08 33.4 6.2 1.5 1 0 0 1 1 1 1 PHD-finger DivIC PF04977.10 KKK15203.1 - 0.05 13.0 0.3 0.075 12.5 0.2 1.2 1 0 0 1 1 1 0 Septum formation initiator zf-HC5HC2H PF13771.1 KKK15203.1 - 0.21 11.7 3.9 0.42 10.8 2.7 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain Prok-RING_1 PF14446.1 KKK15203.1 - 3.3 7.5 10.7 1.6 8.5 4.2 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 PHD_2 PF13831.1 KKK15203.1 - 3.3 7.0 8.0 0.29 10.4 1.6 2.1 2 0 0 2 2 2 0 PHD-finger SnoaL PF07366.7 KKK15204.1 - 9e-05 22.0 0.0 0.00015 21.3 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.2 KKK15204.1 - 0.00087 19.6 0.0 0.0019 18.6 0.0 1.5 1 0 0 1 1 1 1 SnoaL-like domain Med4 PF10018.4 KKK15205.1 - 3.1e-51 173.4 0.3 6.1e-51 172.5 0.0 1.5 2 0 0 2 2 2 1 Vitamin-D-receptor interacting Mediator subunit 4 Dynamin_N PF00350.18 KKK15206.1 - 2.1e-33 115.5 0.0 3.4e-33 114.8 0.0 1.3 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 KKK15206.1 - 4e-15 55.3 0.3 4.8e-14 51.8 0.0 2.3 1 1 2 3 3 3 1 Dynamin central region MMR_HSR1 PF01926.18 KKK15206.1 - 8.1e-05 22.5 0.0 0.0004 20.3 0.0 2.2 2 1 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 KKK15206.1 - 0.0014 19.1 0.0 0.0049 17.3 0.0 2.0 2 0 0 2 2 2 1 Miro-like protein AAA_23 PF13476.1 KKK15206.1 - 0.013 15.8 0.1 0.18 12.1 0.0 2.2 2 1 0 2 2 2 0 AAA domain AAA_21 PF13304.1 KKK15206.1 - 0.023 14.6 0.0 0.044 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 KKK15206.1 - 0.075 12.5 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain MS_channel PF00924.13 KKK15222.1 - 6.5e-21 74.6 1.2 1.1e-20 73.8 0.8 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.27 KKK15222.1 - 5.5e-05 22.1 0.4 0.00013 21.0 0.3 1.7 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 KKK15222.1 - 0.00042 19.9 0.1 0.0023 17.6 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.1 KKK15222.1 - 0.0013 18.7 0.2 0.0037 17.3 0.2 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.1 KKK15222.1 - 0.13 11.6 0.1 0.42 10.0 0.0 1.8 1 0 0 1 1 1 0 EF hand Mgm101p PF06420.7 KKK15223.1 - 1.1e-89 298.1 0.0 1.4e-89 297.8 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 Zn_clus PF00172.13 KKK15224.1 - 5.3e-08 32.6 11.8 1e-07 31.7 8.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain F-box-like PF12937.2 KKK15261.1 - 0.052 13.2 1.0 0.45 10.2 0.9 2.5 2 1 0 2 2 2 0 F-box-like DIM1 PF02966.11 KKK15262.1 - 1.7e-69 231.5 0.3 1.9e-69 231.3 0.2 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Translin PF01997.11 KKK15263.1 - 3.9e-52 176.7 0.0 4.5e-52 176.5 0.0 1.0 1 0 0 1 1 1 1 Translin family GMP_synt_C PF00958.17 KKK15263.1 - 0.05 13.3 0.0 0.2 11.3 0.0 2.0 2 0 0 2 2 2 0 GMP synthase C terminal domain DUF2336 PF10098.4 KKK15263.1 - 0.056 12.6 1.0 0.084 12.1 0.4 1.4 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2336) GSHPx PF00255.14 KKK15264.1 - 1.5e-38 130.5 0.0 1.9e-38 130.1 0.0 1.2 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.16 KKK15264.1 - 0.003 17.2 0.0 0.0059 16.2 0.0 1.6 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 KKK15264.1 - 0.029 13.8 0.1 0.039 13.4 0.1 1.5 1 1 0 1 1 1 0 Redoxin Pcc1 PF09341.5 KKK15265.1 - 3e-27 94.4 0.0 3.6e-27 94.1 0.0 1.1 1 0 0 1 1 1 1 Transcription factor Pcc1 Glycoprotein_B PF00606.13 KKK15266.1 - 0.035 12.1 1.4 0.043 11.8 1.0 1.1 1 0 0 1 1 1 0 Herpesvirus Glycoprotein B DUF4257 PF14074.1 KKK15266.1 - 0.69 9.6 5.1 3.9 7.1 3.5 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF4257) Phage_holin_1 PF04531.8 KKK15266.1 - 1.7 8.7 4.6 1 9.4 0.5 2.4 1 1 2 3 3 3 0 Bacteriophage holin Synuclein PF01387.12 KKK15266.1 - 5.8 6.8 10.8 18 5.2 7.5 1.8 1 1 1 2 2 2 0 Synuclein DSPn PF14671.1 KKK15267.1 - 7.6e-46 155.6 0.0 1.6e-42 144.8 0.0 3.2 3 0 0 3 3 3 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.15 KKK15267.1 - 6.2e-16 58.1 0.0 2.8e-15 56.0 0.0 2.0 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KKK15267.1 - 2.6e-06 26.9 0.0 4.5e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.8 KKK15267.1 - 0.023 14.0 0.0 0.043 13.1 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family LptE PF04390.7 KKK15267.1 - 0.09 12.5 0.1 0.16 11.6 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide-assembly Fungal_trans_2 PF11951.3 KKK15268.1 - 1.4e-08 33.7 0.5 2.4e-08 32.9 0.4 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK15268.1 - 1.6e-07 31.0 8.7 2.9e-07 30.2 6.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KKK15270.1 - 2.8e-31 108.3 0.0 4.8e-31 107.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK15270.1 - 2.4e-11 43.3 12.6 4.1e-11 42.6 8.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gal4_dimer PF03902.8 KKK15270.1 - 0.21 11.5 0.3 0.91 9.4 0.1 2.1 2 0 0 2 2 2 0 Gal4-like dimerisation domain Beta_elim_lyase PF01212.16 KKK15271.1 - 8.8e-40 136.6 0.0 1.1e-39 136.2 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Fungal_trans PF04082.13 KKK15271.1 - 9.4e-07 27.9 0.2 1.5e-06 27.3 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Aminotran_1_2 PF00155.16 KKK15271.1 - 0.00049 19.1 0.0 0.00076 18.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 KKK15271.1 - 0.00067 18.4 0.0 0.001 17.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Zn_clus PF00172.13 KKK15271.1 - 0.012 15.4 3.9 0.026 14.4 2.7 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Met_gamma_lyase PF06838.6 KKK15271.1 - 0.14 10.4 0.0 0.2 9.9 0.0 1.1 1 0 0 1 1 1 0 Methionine gamma-lyase PHD PF00628.24 KKK15272.1 - 1e-11 44.3 7.7 2.3e-11 43.1 5.3 1.7 1 0 0 1 1 1 1 PHD-finger APH PF01636.18 KKK15272.1 - 0.051 13.3 0.0 0.28 10.8 0.0 2.1 1 1 0 1 1 1 0 Phosphotransferase enzyme family Fungal_trans_2 PF11951.3 KKK15273.1 - 8.3e-05 21.3 0.0 0.00043 18.9 0.0 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain DUF2753 PF10952.3 KKK15273.1 - 0.16 11.9 0.2 0.55 10.2 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2753) Amino_oxidase PF01593.19 KKK15274.1 - 1.5e-43 149.5 0.4 1.3e-27 96.9 0.1 2.5 2 1 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KKK15274.1 - 7.6e-14 51.4 0.6 1.6e-13 50.4 0.4 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 KKK15274.1 - 2.4e-07 31.0 0.3 1.3e-05 25.3 0.2 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KKK15274.1 - 7.9e-07 28.9 0.4 0.0041 16.9 0.2 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox PF00070.22 KKK15274.1 - 1e-06 29.0 0.1 1.9e-06 28.1 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KKK15274.1 - 2.6e-05 22.8 1.2 2.9e-05 22.7 0.2 1.5 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.9 KKK15274.1 - 3.6e-05 23.7 1.0 0.00034 20.5 0.3 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KKK15274.1 - 9.8e-05 21.4 0.4 0.0002 20.3 0.1 1.6 1 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KKK15274.1 - 0.00031 19.7 1.0 0.00045 19.1 0.7 1.2 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 KKK15274.1 - 0.00043 19.4 0.1 0.00078 18.5 0.1 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.14 KKK15274.1 - 0.0016 17.5 0.1 0.0024 16.9 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.17 KKK15274.1 - 0.0037 16.1 0.5 0.0058 15.5 0.3 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.16 KKK15274.1 - 0.012 15.1 0.2 0.023 14.2 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.13 KKK15274.1 - 0.022 14.4 1.3 0.031 13.9 0.2 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_oxidored PF12831.2 KKK15274.1 - 0.046 12.7 0.8 0.072 12.1 0.6 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_10 PF13460.1 KKK15274.1 - 0.047 13.7 0.4 0.079 12.9 0.3 1.3 1 0 0 1 1 1 0 NADH(P)-binding UDPG_MGDP_dh_N PF03721.9 KKK15274.1 - 0.074 12.4 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_7 PF13241.1 KKK15274.1 - 0.13 12.4 0.1 0.27 11.5 0.1 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding FMO-like PF00743.14 KKK15274.1 - 0.17 10.0 0.0 0.29 9.2 0.0 1.3 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like PhyH PF05721.8 KKK15275.1 - 1.3e-18 67.8 0.0 2e-18 67.2 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF2235 PF09994.4 KKK15276.1 - 3.9e-114 380.7 0.4 5.1e-114 380.3 0.3 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Sugar_tr PF00083.19 KKK15278.1 - 3.1e-97 325.9 26.8 3.5e-97 325.8 18.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KKK15278.1 - 2.5e-32 111.9 46.8 6e-28 97.5 16.6 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KKK15278.1 - 0.00046 18.5 1.0 0.00081 17.7 0.7 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF3180 PF11377.3 KKK15278.1 - 0.034 13.9 3.9 0.3 10.9 0.7 2.9 1 1 0 2 2 2 0 Protein of unknown function (DUF3180) SKG6 PF08693.5 KKK15279.1 - 0.0052 16.0 0.2 0.009 15.2 0.1 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Adeno_E3_CR2 PF02439.10 KKK15279.1 - 0.015 14.8 0.1 0.021 14.3 0.0 1.2 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 EphA2_TM PF14575.1 KKK15279.1 - 0.11 12.8 0.0 0.13 12.6 0.0 1.2 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Homeobox PF00046.24 KKK15280.1 - 7.4e-15 54.3 3.2 1.6e-14 53.2 2.2 1.6 1 0 0 1 1 1 1 Homeobox domain Cation_efflux PF01545.16 KKK15281.1 - 5.7e-37 127.3 10.9 7.5e-37 126.9 7.5 1.1 1 0 0 1 1 1 1 Cation efflux family An_peroxidase PF03098.10 KKK15282.1 - 4.3e-94 315.7 0.0 7e-92 308.5 0.0 2.2 1 1 0 1 1 1 1 Animal haem peroxidase Pkinase PF00069.20 KKK15317.1 - 2e-62 210.6 0.0 2.6e-62 210.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK15317.1 - 1e-30 106.7 0.0 1.5e-30 106.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KKK15317.1 - 0.084 11.8 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 Kinase-like APH PF01636.18 KKK15317.1 - 0.097 12.3 0.0 0.68 9.6 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family zf-UBR PF02207.15 KKK15318.1 - 2e-16 59.4 4.6 2e-16 59.4 3.2 3.3 3 0 0 3 3 3 1 Putative zinc finger in N-recognin (UBR box) BUD22 PF09073.5 KKK15318.1 - 0.017 14.2 9.8 0.026 13.5 6.8 1.2 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.7 KKK15318.1 - 0.085 10.7 10.3 0.12 10.2 7.2 1.1 1 0 0 1 1 1 0 Nop14-like family Pal1 PF08316.6 KKK15320.1 - 2.2e-47 161.0 0.6 6.3e-47 159.5 0.4 1.8 1 0 0 1 1 1 1 Pal1 cell morphology protein MCM PF00493.18 KKK15321.1 - 3.2e-138 460.0 0.0 4.6e-138 459.5 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM2_N PF12619.3 KKK15321.1 - 1.1e-31 109.9 43.9 1.1e-31 109.9 30.4 2.5 3 0 0 3 3 3 1 Mini-chromosome maintenance protein 2 MCM_N PF14551.1 KKK15321.1 - 1e-17 64.7 0.0 2.3e-17 63.6 0.0 1.6 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 KKK15321.1 - 3.9e-09 35.9 0.1 9.4e-07 28.1 0.0 2.5 1 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 KKK15321.1 - 4.2e-06 26.5 0.0 9.7e-06 25.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 KKK15321.1 - 0.0011 18.5 0.0 0.0056 16.2 0.0 2.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 KKK15321.1 - 0.0019 17.6 0.2 0.013 14.9 0.1 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain Zn_ribbon_2 PF12674.2 KKK15321.1 - 0.079 13.3 0.6 0.38 11.1 0.6 2.0 2 0 0 2 2 2 0 Putative zinc ribbon domain zf-TFIIB PF13453.1 KKK15321.1 - 0.29 10.3 1.3 0.62 9.3 0.9 1.6 1 0 0 1 1 1 0 Transcription factor zinc-finger Med31 PF05669.7 KKK15322.1 - 4.4e-30 103.4 0.0 5.4e-30 103.1 0.0 1.1 1 0 0 1 1 1 1 SOH1 Tcf25 PF04910.9 KKK15322.1 - 0.028 13.3 0.0 0.033 13.1 0.0 1.1 1 0 0 1 1 1 0 Transcriptional repressor TCF25 Alk_phosphatase PF00245.15 KKK15323.1 - 1.8e-60 204.8 0.0 4.1e-60 203.6 0.0 1.6 1 1 0 1 1 1 1 Alkaline phosphatase Sulfatase PF00884.18 KKK15323.1 - 1.1e-06 28.0 0.7 4.6e-06 26.0 0.5 2.1 2 1 0 2 2 2 1 Sulfatase Phosphodiest PF01663.17 KKK15323.1 - 7.9e-06 25.4 0.2 1.5e-05 24.5 0.2 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase FTA4 PF13093.1 KKK15323.1 - 0.00078 18.9 0.0 0.0011 18.4 0.0 1.1 1 0 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 DUF229 PF02995.12 KKK15323.1 - 0.0022 16.4 0.1 0.0039 15.6 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF229) HHH_3 PF12836.2 KKK15323.1 - 0.05 13.5 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix motif Metalloenzyme PF01676.13 KKK15323.1 - 0.061 12.7 0.5 0.12 11.6 0.3 1.4 1 0 0 1 1 1 0 Metalloenzyme superfamily Peptidase_C16 PF01831.12 KKK15323.1 - 0.14 11.6 0.0 0.26 10.7 0.0 1.4 1 0 0 1 1 1 0 Peptidase C16 family Palm_thioest PF02089.10 KKK15325.1 - 8.9e-62 208.5 0.0 1.1e-61 208.2 0.0 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_6 PF12697.2 KKK15325.1 - 0.0017 18.2 0.0 0.0043 16.9 0.0 1.7 1 1 1 2 2 2 1 Alpha/beta hydrolase family DUF915 PF06028.6 KKK15325.1 - 0.0048 16.0 0.0 0.0088 15.1 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_1 PF00561.15 KKK15325.1 - 0.031 13.8 0.0 0.047 13.2 0.0 1.4 1 1 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 KKK15325.1 - 0.071 12.5 0.1 7.9 5.8 0.0 2.2 1 1 1 2 2 2 0 Phospholipase/Carboxylesterase RNA_pol_Rpb4 PF03874.11 KKK15345.1 - 2.8e-27 95.0 2.3 3.4e-27 94.7 1.6 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 Met_10 PF02475.11 KKK15346.1 - 4.9e-65 218.8 0.0 7.2e-65 218.3 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Sugar_tr PF00083.19 KKK15347.1 - 1.8e-75 254.2 23.5 3.7e-66 223.5 7.3 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 KKK15347.1 - 1.7e-22 79.6 19.9 5e-22 78.0 13.8 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Fungal_trans PF04082.13 KKK15348.1 - 4.1e-20 71.7 0.0 7.7e-20 70.8 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK15348.1 - 0.00076 19.3 5.9 0.0014 18.4 4.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-GRF PF06839.7 KKK15349.1 - 1.2e-06 28.3 5.1 2.4e-06 27.3 3.6 1.5 1 0 0 1 1 1 1 GRF zinc finger DPPIV_N PF00930.16 KKK15350.1 - 1.9e-114 381.9 0.0 2.5e-114 381.5 0.0 1.1 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 KKK15350.1 - 3.1e-55 186.7 3.1 4.4e-55 186.1 2.1 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KKK15350.1 - 2.8e-09 36.8 0.0 5.6e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KKK15350.1 - 2.8e-06 27.3 0.1 2.7e-05 24.1 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 KKK15350.1 - 0.00014 21.4 0.2 0.00035 20.0 0.1 1.6 1 1 0 1 1 1 1 Putative esterase Peptidase_S15 PF02129.13 KKK15350.1 - 0.00014 21.3 3.7 0.00095 18.6 0.9 2.2 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) PAF-AH_p_II PF03403.8 KKK15350.1 - 0.00073 17.9 0.0 0.26 9.5 0.0 2.2 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II DLH PF01738.13 KKK15350.1 - 0.02 14.1 0.1 0.075 12.3 0.1 1.8 1 1 0 1 1 1 0 Dienelactone hydrolase family Abhydrolase_2 PF02230.11 KKK15350.1 - 0.039 13.4 0.1 1.7 8.0 0.1 2.1 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase DUF3818 PF12825.2 KKK15351.1 - 2.1e-139 463.9 2.2 3e-139 463.4 1.5 1.2 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.2 KKK15351.1 - 6.3e-43 145.6 0.4 1.2e-42 144.7 0.3 1.4 1 0 0 1 1 1 1 PX-associated PX PF00787.19 KKK15351.1 - 3.2e-14 52.6 0.7 1.2e-13 50.8 0.1 2.3 2 1 0 2 2 2 1 PX domain DUF2373 PF10180.4 KKK15351.1 - 0.1 12.1 0.6 0.27 10.7 0.4 1.6 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2373) Glyco_hydro_114 PF03537.8 KKK15352.1 - 1.1e-28 98.7 0.1 1.9e-28 98.0 0.1 1.4 1 0 0 1 1 1 1 Glycoside-hydrolase family GH114 Glycos_transf_1 PF00534.15 KKK15353.1 - 1.4e-12 47.3 0.0 3.6e-12 46.0 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 KKK15353.1 - 8.8e-05 22.6 0.0 0.00031 20.8 0.0 2.0 1 0 0 1 1 1 1 Glycosyl transferases group 1 DUF3492 PF11997.3 KKK15353.1 - 0.00011 21.8 0.0 0.0011 18.5 0.0 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF3492) GST_N_3 PF13417.1 KKK15356.1 - 1e-08 35.2 0.1 2.6e-08 33.9 0.1 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KKK15356.1 - 7.7e-06 25.7 0.0 1.3e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 KKK15356.1 - 0.00064 19.6 0.0 0.0015 18.4 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KKK15356.1 - 0.0021 17.9 0.0 0.0035 17.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KKK15356.1 - 0.15 12.5 0.0 0.22 11.9 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain PI-PLC-X PF00388.14 KKK15357.1 - 3.3e-58 195.2 0.0 5.3e-58 194.5 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 KKK15357.1 - 3e-36 123.9 0.0 5.2e-36 123.2 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain Epimerase PF01370.16 KKK15358.1 - 1.6e-34 119.3 0.0 3.7e-34 118.1 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Epimerase_Csub PF13950.1 KKK15358.1 - 2.8e-12 46.4 0.0 5.6e-12 45.4 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit Polysacc_synt_2 PF02719.10 KKK15358.1 - 2.4e-08 33.2 0.0 7.9e-07 28.2 0.0 2.4 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.7 KKK15358.1 - 3e-06 26.3 0.0 1.2e-05 24.3 0.0 1.9 1 1 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.14 KKK15358.1 - 1.6e-05 23.7 0.0 0.00017 20.4 0.0 2.4 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.5 KKK15358.1 - 8e-05 22.3 0.0 0.00015 21.5 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 KKK15358.1 - 0.00026 20.9 0.0 0.00049 20.0 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.12 KKK15358.1 - 0.00036 19.5 0.0 0.011 14.6 0.0 2.8 2 1 0 2 2 2 1 RmlD substrate binding domain PQQ PF01011.16 KKK15358.1 - 0.068 12.7 0.0 0.16 11.5 0.0 1.6 1 0 0 1 1 1 0 PQQ enzyme repeat Ribosomal_L37 PF08561.5 KKK15359.1 - 4.6e-30 103.0 6.4 5.4e-29 99.5 4.4 2.1 1 1 0 1 1 1 1 Mitochondrial ribosomal protein L37 LELP1 PF15042.1 KKK15359.1 - 6.8 6.9 10.2 32 4.7 6.1 2.2 2 0 0 2 2 2 0 Late cornified envelope-like proline-rich protein 1 Spherulin4 PF12138.3 KKK15360.1 - 7.7e-73 245.0 0.1 9.2e-73 244.7 0.1 1.1 1 0 0 1 1 1 1 Spherulation-specific family 4 OapA_N PF08525.6 KKK15360.1 - 0.82 9.5 7.5 1.4 8.7 5.2 1.4 1 0 0 1 1 1 0 Opacity-associated protein A N-terminal motif Fungal_trans_2 PF11951.3 KKK15361.1 - 6.3e-15 54.6 8.3 2.2e-14 52.9 5.8 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans PF04082.13 KKK15361.1 - 0.023 13.5 0.3 0.023 13.5 0.2 1.7 2 0 0 2 2 2 0 Fungal specific transcription factor domain BNR PF02012.15 KKK15376.1 - 0.043 13.6 0.1 0.38 10.7 0.1 2.8 1 0 0 1 1 1 0 BNR/Asp-box repeat AAA PF00004.24 KKK15377.1 - 3.3e-41 140.5 0.0 1.2e-37 128.9 0.0 2.9 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 KKK15377.1 - 2.8e-05 24.0 0.0 0.0049 16.7 0.0 3.1 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 KKK15377.1 - 5.4e-05 22.3 0.0 0.00017 20.7 0.0 1.8 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 KKK15377.1 - 6.4e-05 23.0 4.8 0.0049 16.8 0.0 4.3 3 1 2 5 5 5 1 AAA ATPase domain AAA_22 PF13401.1 KKK15377.1 - 0.0001 22.4 0.7 0.0029 17.7 0.1 2.9 2 1 0 2 2 1 1 AAA domain TIP49 PF06068.8 KKK15377.1 - 0.00027 19.7 0.0 0.00062 18.5 0.0 1.5 1 0 0 1 1 1 1 TIP49 C-terminus AAA_17 PF13207.1 KKK15377.1 - 0.00064 20.5 0.0 0.0032 18.2 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KKK15377.1 - 0.00085 19.0 0.0 0.0024 17.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 KKK15377.1 - 0.0011 18.7 0.4 0.0038 16.9 0.2 2.0 1 0 0 1 1 1 1 Part of AAA domain AAA_28 PF13521.1 KKK15377.1 - 0.0024 17.8 0.2 0.013 15.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 KKK15377.1 - 0.0046 16.3 0.0 0.0086 15.5 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.1 KKK15377.1 - 0.0049 16.7 0.0 0.027 14.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 KKK15377.1 - 0.016 14.3 0.0 0.037 13.1 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_2 PF07724.9 KKK15377.1 - 0.019 14.8 0.0 0.39 10.5 0.0 2.9 3 1 0 3 3 3 0 AAA domain (Cdc48 subfamily) RNA_helicase PF00910.17 KKK15377.1 - 0.024 14.8 0.0 0.067 13.3 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.1 KKK15377.1 - 0.048 13.9 0.0 0.17 12.1 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 KKK15377.1 - 0.055 13.0 0.2 0.15 11.6 0.2 1.7 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 KKK15377.1 - 0.068 12.5 0.7 6.8 6.0 0.0 3.0 2 1 1 3 3 3 0 AAA-like domain IPT PF01745.11 KKK15377.1 - 0.081 12.0 0.1 0.45 9.6 0.0 2.0 2 0 0 2 2 2 0 Isopentenyl transferase DUF4050 PF13259.1 KKK15378.1 - 4.7e-45 152.4 0.1 7.3e-45 151.8 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4050) Mus7 PF09462.5 KKK15379.1 - 4.7e-223 742.4 0.0 7.5e-223 741.8 0.0 1.3 1 0 0 1 1 1 1 Mus7/MMS22 family PAPA-1 PF04795.7 KKK15380.1 - 5.2e-30 103.9 5.5 5.2e-30 103.9 3.8 2.5 3 0 0 3 3 3 1 PAPA-1-like conserved region Pex14_N PF04695.8 KKK15381.1 - 5.1e-30 104.2 0.0 5.1e-30 104.2 0.0 2.6 2 1 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Ebola_NP PF05505.7 KKK15381.1 - 2.7 5.9 6.0 4.4 5.2 4.2 1.3 1 0 0 1 1 1 0 Ebola nucleoprotein Aldolase_II PF00596.16 KKK15382.1 - 3.3e-06 26.8 0.0 4.5e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain DER1 PF04511.10 KKK15408.1 - 2.7e-51 173.8 3.8 3.1e-51 173.7 2.6 1.0 1 0 0 1 1 1 1 Der1-like family Histone PF00125.19 KKK15409.1 - 2e-27 95.1 0.2 2.9e-27 94.6 0.2 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 KKK15409.1 - 0.0012 18.9 0.1 0.0017 18.4 0.1 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 KKK15409.1 - 0.048 13.7 0.4 0.1 12.7 0.3 1.4 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 KKK15409.1 - 0.09 12.0 0.2 0.1 11.8 0.1 1.3 1 1 0 1 1 1 0 Centromere kinetochore component CENP-T LamB_YcsF PF03746.11 KKK15429.1 - 4.6e-10 39.0 0.0 5.1e-10 38.8 0.0 1.0 1 0 0 1 1 1 1 LamB/YcsF family AHS2 PF02626.10 KKK15430.1 - 1.7e-74 250.5 0.0 2.3e-74 250.1 0.0 1.2 1 0 0 1 1 1 1 Allophanate hydrolase subunit 2 CPSase_L_D2 PF02786.12 KKK15430.1 - 5.6e-54 182.6 0.0 9.8e-54 181.8 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 KKK15430.1 - 4.1e-38 129.8 0.0 9e-38 128.7 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 KKK15430.1 - 4.4e-34 116.6 0.0 7.2e-34 115.9 0.0 1.4 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain ATP-grasp_4 PF13535.1 KKK15430.1 - 7.5e-15 55.1 0.0 1.2e-14 54.4 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 KKK15430.1 - 2.5e-12 46.1 0.0 3.6e-11 42.3 0.0 2.0 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Biotin_lipoyl PF00364.17 KKK15430.1 - 7.5e-11 41.5 0.3 1.1e-09 37.7 0.2 2.6 2 0 0 2 2 2 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.8 KKK15430.1 - 6e-06 25.7 0.0 1.1e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.1 KKK15430.1 - 0.013 15.1 1.8 2.9 7.6 0.1 3.7 4 0 0 4 4 4 0 Biotin-lipoyl like RimK PF08443.6 KKK15430.1 - 0.018 14.5 0.0 0.048 13.1 0.0 1.7 1 1 0 1 1 1 0 RimK-like ATP-grasp domain ATP-grasp_5 PF13549.1 KKK15430.1 - 0.028 13.6 0.0 0.055 12.6 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain ATP-grasp PF02222.17 KKK15430.1 - 0.028 13.7 0.0 0.045 13.1 0.0 1.3 1 0 0 1 1 1 0 ATP-grasp domain UQ_con PF00179.21 KKK15431.1 - 1.1e-10 41.0 0.1 2e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 KKK15431.1 - 0.0095 15.8 0.0 0.015 15.1 0.0 1.5 1 0 0 1 1 1 1 RWD domain Glycos_transf_4 PF00953.16 KKK15431.1 - 0.14 11.9 0.1 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 4 Homeobox_KN PF05920.6 KKK15432.1 - 5.8e-16 57.9 0.8 1.5e-15 56.5 0.6 1.8 1 0 0 1 1 1 1 Homeobox KN domain zf-C2H2_4 PF13894.1 KKK15432.1 - 4.5e-05 23.4 16.3 0.0046 17.1 1.1 4.9 3 1 0 3 3 3 2 C2H2-type zinc finger Homeobox PF00046.24 KKK15432.1 - 0.00028 20.4 0.5 0.00065 19.2 0.4 1.7 1 0 0 1 1 1 1 Homeobox domain HTH_Tnp_Tc5 PF03221.11 KKK15432.1 - 0.0012 18.5 0.0 0.0028 17.4 0.0 1.6 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HA PF03457.9 KKK15432.1 - 0.013 15.5 0.1 0.033 14.2 0.0 1.7 1 0 0 1 1 1 0 Helicase associated domain zf-C2H2 PF00096.21 KKK15432.1 - 0.039 14.3 19.7 0.43 11.0 0.9 4.8 4 0 0 4 4 4 0 Zinc finger, C2H2 type DUF605 PF04652.11 KKK15432.1 - 0.29 10.4 4.9 0.52 9.6 3.4 1.3 1 0 0 1 1 1 0 Vta1 like Cupin_8 PF13621.1 KKK15433.1 - 1.5e-34 119.6 0.1 2.6e-34 118.8 0.1 1.3 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 KKK15433.1 - 1.7e-07 30.8 0.0 0.0015 17.8 0.0 2.3 2 0 0 2 2 2 2 Cupin superfamily protein JmjC PF02373.17 KKK15433.1 - 0.00081 19.6 0.0 0.0017 18.5 0.0 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_2 PF07883.6 KKK15433.1 - 0.08 12.4 0.0 0.21 11.1 0.0 1.6 1 0 0 1 1 1 0 Cupin domain GTP1_OBG PF01018.17 KKK15434.1 - 1.4e-40 138.5 4.0 2.8e-30 105.0 2.3 2.3 2 0 0 2 2 2 2 GTP1/OBG MMR_HSR1 PF01926.18 KKK15434.1 - 2.3e-21 75.8 0.0 4.1e-21 75.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KKK15434.1 - 1.2e-08 34.3 0.1 2.9e-08 33.1 0.1 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B ArgK PF03308.11 KKK15434.1 - 4e-05 22.5 0.0 0.17 10.6 0.0 2.2 2 0 0 2 2 2 2 ArgK protein GTP_EFTU PF00009.22 KKK15434.1 - 0.0026 17.2 0.0 2 7.8 0.0 2.2 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain ABC_tran PF00005.22 KKK15434.1 - 0.017 15.4 1.7 0.044 14.0 0.0 2.1 2 0 0 2 2 2 0 ABC transporter Miro PF08477.8 KKK15434.1 - 0.018 15.4 0.0 0.085 13.3 0.0 2.1 2 1 0 2 2 2 0 Miro-like protein Dynamin_N PF00350.18 KKK15434.1 - 0.026 14.3 0.0 0.77 9.5 0.0 2.3 1 1 1 2 2 2 0 Dynamin family 2OG-FeII_Oxy_2 PF13532.1 KKK15435.1 - 4.7e-34 117.9 0.0 6.7e-34 117.4 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily zf-GRF PF06839.7 KKK15435.1 - 0.00044 20.1 5.5 0.00079 19.3 3.8 1.4 1 0 0 1 1 1 1 GRF zinc finger DUF1444 PF07285.6 KKK15435.1 - 0.11 11.7 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1444) EGF_MSP1_1 PF12946.2 KKK15435.1 - 0.13 12.0 0.0 8.5 6.2 0.3 2.6 2 0 0 2 2 2 0 MSP1 EGF domain 1 IMS PF00817.15 KKK15436.1 - 9.2e-34 116.3 0.0 3.5e-32 111.2 0.0 2.2 1 1 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 KKK15436.1 - 2.8e-13 49.9 0.0 4.9e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 KKK15436.1 - 0.023 14.7 0.0 0.048 13.7 0.0 1.6 1 0 0 1 1 1 0 IMS family HHH motif DUF765 PF05570.6 KKK15436.1 - 0.066 13.1 1.5 0.11 12.4 0.1 2.0 2 0 0 2 2 2 0 Circovirus protein of unknown function (DUF765) WSC PF01822.14 KKK15438.1 - 1.6e-06 27.8 14.3 1.6e-06 27.8 9.9 3.5 2 1 0 2 2 2 1 WSC domain Podoplanin PF05808.6 KKK15438.1 - 2.3e-06 27.2 7.0 3.8e-06 26.5 4.8 1.4 1 0 0 1 1 1 1 Podoplanin IncA PF04156.9 KKK15438.1 - 0.051 13.1 0.1 0.095 12.2 0.1 1.4 1 0 0 1 1 1 0 IncA protein TrbL PF04610.9 KKK15438.1 - 0.23 11.1 4.9 0.13 11.9 1.7 1.9 2 0 0 2 2 2 0 TrbL/VirB6 plasmid conjugal transfer protein Trp_oprn_chp PF09534.5 KKK15438.1 - 0.28 10.7 4.8 0.16 11.5 1.6 1.9 2 1 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF1206 PF06724.6 KKK15438.1 - 5.1 6.9 9.3 1.3 8.8 3.4 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1206) TMEM154 PF15102.1 KKK15438.1 - 5.1 6.7 8.3 20 4.8 5.8 2.0 1 1 0 1 1 1 0 TMEM154 protein family DUF3445 PF11927.3 KKK15439.1 - 7.4e-78 261.3 0.0 1.1e-77 260.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Pkinase PF00069.20 KKK15440.1 - 0.00082 18.5 0.0 0.001 18.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK15440.1 - 0.051 12.6 0.0 0.061 12.3 0.0 1.1 1 0 0 1 1 1 0 Protein tyrosine kinase WD40 PF00400.27 KKK15441.1 - 2.8e-20 71.3 3.4 0.038 13.8 0.0 7.5 7 0 0 7 7 7 6 WD domain, G-beta repeat Nop14 PF04147.7 KKK15441.1 - 0.75 7.6 9.7 1.1 7.1 6.7 1.1 1 0 0 1 1 1 0 Nop14-like family Glypican PF01153.14 KKK15441.1 - 2.3 6.7 3.1 3.3 6.1 2.1 1.1 1 0 0 1 1 1 0 Glypican Fungal_trans PF04082.13 KKK15442.1 - 1.1e-15 57.2 0.3 1.1e-15 57.2 0.2 2.2 3 0 0 3 3 3 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 KKK15442.1 - 1.6e-06 28.0 9.4 0.00033 20.8 2.4 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KKK15442.1 - 2.7e-06 27.3 2.5 2.7e-06 27.3 1.7 2.7 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 KKK15442.1 - 5.2e-06 26.4 8.6 0.0013 18.9 2.5 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KKK15442.1 - 0.059 13.5 1.7 0.076 13.1 0.4 1.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding AAA_12 PF13087.1 KKK15443.1 - 2.3e-36 125.0 0.0 3.6e-36 124.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KKK15443.1 - 7.8e-23 81.2 0.0 4.1e-22 78.9 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KKK15443.1 - 2.9e-07 30.1 0.0 6.7e-07 28.9 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 KKK15443.1 - 2.5e-06 27.2 0.1 0.00015 21.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.13 KKK15443.1 - 3.9e-05 23.2 0.0 0.018 14.5 0.0 3.3 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase DEAD PF00270.24 KKK15443.1 - 0.0014 18.1 0.0 0.0032 16.9 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase PhoH PF02562.11 KKK15443.1 - 0.0038 16.4 0.0 0.0094 15.1 0.0 1.6 1 0 0 1 1 1 1 PhoH-like protein DUF2075 PF09848.4 KKK15443.1 - 0.023 13.6 0.1 0.13 11.2 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_25 PF13481.1 KKK15443.1 - 0.056 12.8 0.0 0.42 9.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain ParA PF10609.4 KKK15443.1 - 0.061 13.2 0.0 0.22 11.4 0.0 2.0 1 0 0 1 1 1 0 ParA/MinD ATPase like IstB_IS21 PF01695.12 KKK15443.1 - 0.067 12.5 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein ResIII PF04851.10 KKK15443.1 - 0.076 12.8 0.0 0.31 10.8 0.0 2.0 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Helicase_RecD PF05127.9 KKK15443.1 - 0.1 12.1 0.0 3.8 7.1 0.0 2.4 2 0 0 2 2 2 0 Helicase UvrD-helicase PF00580.16 KKK15443.1 - 0.11 11.7 0.1 0.31 10.2 0.0 1.8 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain HA2 PF04408.18 KKK15444.1 - 5.1e-29 100.2 0.2 2.2e-28 98.2 0.1 2.2 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 KKK15444.1 - 3.6e-26 91.2 0.0 1.4e-25 89.3 0.0 2.0 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 KKK15444.1 - 3.7e-12 45.9 0.0 8.1e-12 44.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain S1 PF00575.18 KKK15444.1 - 3.6e-10 39.7 1.0 7.2e-10 38.8 0.7 1.5 1 0 0 1 1 1 1 S1 RNA binding domain DEAD PF00270.24 KKK15444.1 - 2.1e-05 24.1 0.0 4.5e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KKK15444.1 - 0.00011 22.3 0.0 0.00033 20.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 KKK15444.1 - 0.00023 20.1 0.0 0.00065 18.6 0.0 1.7 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.1 KKK15444.1 - 0.015 15.0 0.2 0.042 13.6 0.1 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_14 PF13173.1 KKK15444.1 - 0.11 12.4 0.1 1.3 8.9 0.1 2.6 1 1 0 1 1 1 0 AAA domain PRP38 PF03371.10 KKK15446.1 - 7.8e-67 224.2 0.0 9.7e-67 223.9 0.0 1.1 1 0 0 1 1 1 1 PRP38 family Transp_cyt_pur PF02133.10 KKK15455.1 - 9.8e-28 96.8 31.2 1.3e-27 96.4 21.6 1.2 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF3938 PF13074.1 KKK15455.1 - 0.68 9.8 6.4 1.2 9.0 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3938) Dak1 PF02733.12 KKK15456.1 - 1.3e-103 346.0 0.0 1.7e-103 345.6 0.0 1.1 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.12 KKK15456.1 - 5.8e-39 133.5 0.9 9.2e-39 132.8 0.6 1.3 1 0 0 1 1 1 1 DAK2 domain SKG6 PF08693.5 KKK15457.1 - 6.4e-06 25.3 0.5 6.4e-06 25.3 0.3 1.8 2 0 0 2 2 2 1 Transmembrane alpha-helix domain SSP160 PF06933.6 KKK15457.1 - 0.14 10.1 22.3 0.18 9.7 15.5 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Glyco_transf_34 PF05637.7 KKK15458.1 - 1.3e-17 64.1 0.0 3.1e-10 39.9 0.0 2.2 1 1 1 2 2 2 2 galactosyl transferase GMA12/MNN10 family DUF273 PF03314.9 KKK15458.1 - 0.0011 18.2 0.0 0.0017 17.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF273 Pkinase PF00069.20 KKK15459.1 - 3.9e-22 78.6 0.0 1e-21 77.2 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK15459.1 - 1.2e-20 73.6 0.0 3.2e-20 72.2 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 KKK15459.1 - 0.0032 16.8 0.0 0.046 13.0 0.0 2.0 2 0 0 2 2 2 1 RIO1 family PLD_C PF12357.3 KKK15459.1 - 0.0046 16.4 0.0 0.06 12.8 0.0 2.1 2 0 0 2 2 2 1 Phospholipase D C terminal Kdo PF06293.9 KKK15459.1 - 0.061 12.3 0.2 0.1 11.6 0.2 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KKK15459.1 - 0.68 9.6 3.4 0.37 10.4 0.4 1.9 2 1 1 3 3 3 0 Phosphotransferase enzyme family PBP PF01161.15 KKK15460.1 - 2.1e-15 56.8 0.0 2.5e-15 56.6 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein NPP1 PF05630.6 KKK15461.1 - 9.3e-58 195.3 0.0 1.1e-57 195.0 0.0 1.0 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) HLH PF00010.21 KKK15469.1 - 1.4e-11 43.9 1.3 4e-11 42.4 0.9 1.8 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF1319 PF07028.6 KKK15469.1 - 0.0072 16.5 0.2 0.0097 16.0 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1319) Med11 PF10280.4 KKK15469.1 - 0.16 11.9 1.3 0.24 11.4 0.5 1.5 1 1 0 1 1 1 0 Mediator complex protein SR-25 PF10500.4 KKK15469.1 - 0.23 10.9 13.4 0.31 10.4 9.3 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Corona_nucleoca PF00937.13 KKK15469.1 - 1.2 7.9 9.6 1.5 7.7 6.7 1.1 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein MFMR PF07777.6 KKK15469.1 - 1.3 8.9 9.0 1.9 8.4 6.2 1.2 1 0 0 1 1 1 0 G-box binding protein MFMR PAP1 PF08601.5 KKK15469.1 - 2.3 7.8 8.2 2.7 7.5 5.7 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 IMS PF00817.15 KKK15488.1 - 3.4e-41 140.4 2.0 5.5e-41 139.8 0.4 2.1 2 0 0 2 2 2 1 impB/mucB/samB family IMS_C PF11799.3 KKK15488.1 - 9.3e-16 57.9 2.3 2.8e-15 56.3 0.1 2.7 3 0 0 3 3 3 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 KKK15488.1 - 1.7e-05 24.5 0.0 4.7e-05 23.1 0.0 1.8 1 0 0 1 1 1 1 IMS family HHH motif VPS28 PF03997.7 KKK15488.1 - 0.054 13.0 0.2 0.13 11.8 0.2 1.6 1 0 0 1 1 1 0 VPS28 protein FHA PF00498.21 KKK15490.1 - 4.3e-08 33.1 0.2 1.1e-07 31.8 0.1 1.7 1 0 0 1 1 1 1 FHA domain BRCT PF00533.21 KKK15490.1 - 0.00064 19.8 0.0 0.16 12.1 0.0 2.8 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain Exonuc_VII_L PF02601.10 KKK15490.1 - 1.7 7.7 14.5 5.7 6.0 10.0 1.9 1 1 0 1 1 1 0 Exonuclease VII, large subunit F-box-like PF12937.2 KKK15491.1 - 0.0043 16.7 0.0 0.015 15.0 0.0 2.0 1 1 0 1 1 1 1 F-box-like Sugar_tr PF00083.19 KKK15494.1 - 5.5e-96 321.8 26.2 6.8e-96 321.5 18.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KKK15494.1 - 1.2e-26 93.2 30.6 1.2e-26 93.2 21.2 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KKK15494.1 - 4.2e-06 25.2 6.4 4.2e-06 25.2 4.4 1.8 2 1 1 3 3 3 1 Fungal trichothecene efflux pump (TRI12) DUF2970 PF11174.3 KKK15494.1 - 4.2 7.0 9.8 18 5.0 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2970) Myb_DNA-bind_6 PF13921.1 KKK15495.1 - 6.6e-17 61.3 2.7 1.2e-11 44.4 0.3 2.8 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 KKK15495.1 - 2.3e-12 46.7 7.3 4.5e-09 36.2 0.4 3.0 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 KKK15495.1 - 0.0022 18.0 1.9 0.016 15.3 1.3 2.7 1 1 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.4 KKK15495.1 - 0.011 15.9 2.6 2.2 8.5 0.1 3.0 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like UDP-g_GGTase PF06427.6 KKK15496.1 - 1.2e-68 230.5 0.0 2.1e-68 229.7 0.0 1.3 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Glyco_transf_8 PF01501.15 KKK15496.1 - 0.00032 20.0 0.0 0.00058 19.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 8 TauD PF02668.11 KKK15497.1 - 2.2e-20 73.4 0.0 7.8e-20 71.6 0.0 1.8 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Hydrolase_like PF13242.1 KKK15497.1 - 4.1e-10 39.2 0.1 1.5e-09 37.4 0.1 1.9 2 0 0 2 2 2 1 HAD-hyrolase-like HAD_2 PF13419.1 KKK15497.1 - 3.1e-09 37.2 0.0 5.5e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase HAD PF12710.2 KKK15497.1 - 2.4e-06 27.8 0.0 4.3e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KKK15497.1 - 3.2e-05 24.4 0.0 0.011 16.1 0.0 2.2 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase CsiD PF08943.5 KKK15497.1 - 0.00084 18.3 0.0 0.0016 17.3 0.0 1.4 1 1 0 1 1 1 1 CsiD PerC PF06069.6 KKK15498.1 - 0.13 12.2 0.0 0.28 11.2 0.0 1.5 2 0 0 2 2 2 0 PerC transcriptional activator HSP70 PF00012.15 KKK15499.1 - 6.5e-87 291.8 0.8 8.5e-87 291.4 0.6 1.1 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KKK15499.1 - 6.7e-11 41.3 0.2 9.8e-11 40.8 0.1 1.3 1 0 0 1 1 1 1 MreB/Mbl protein FAD_binding_4 PF01565.18 KKK15518.1 - 0.022 14.2 0.1 0.04 13.3 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain eIF2A PF08662.6 KKK15519.1 - 8.8e-70 234.3 0.0 3.9e-39 134.3 0.0 3.2 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A WD40 PF00400.27 KKK15519.1 - 0.0019 18.0 1.9 6.9 6.7 0.1 4.8 4 1 0 4 4 4 2 WD domain, G-beta repeat CDV3 PF15359.1 KKK15519.1 - 0.0057 16.7 0.7 0.0057 16.7 0.5 3.6 3 1 1 4 4 4 1 Carnitine deficiency-associated protein 3 FAT PF02259.18 KKK15524.1 - 4.6e-130 433.7 0.5 4.6e-130 433.7 0.4 1.8 2 0 0 2 2 2 1 FAT domain DUF3385 PF11865.3 KKK15524.1 - 8e-61 204.6 0.8 1.4e-58 197.3 0.2 3.9 4 0 0 4 4 4 1 Domain of unknown function (DUF3385) PI3_PI4_kinase PF00454.22 KKK15524.1 - 3.2e-57 193.6 0.3 5.6e-57 192.9 0.2 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Rapamycin_bind PF08771.6 KKK15524.1 - 2.7e-41 139.6 4.5 8.2e-41 138.1 0.1 4.0 4 0 0 4 4 4 1 Rapamycin binding domain HEAT_2 PF13646.1 KKK15524.1 - 4.9e-17 62.0 11.3 0.00029 21.0 0.0 9.0 8 2 1 9 9 8 3 HEAT repeats FATC PF02260.15 KKK15524.1 - 2.2e-14 52.5 0.8 5.1e-14 51.4 0.6 1.7 1 0 0 1 1 1 1 FATC domain HEAT_EZ PF13513.1 KKK15524.1 - 3.5e-14 52.8 7.4 0.0052 17.2 0.0 10.6 7 3 3 11 11 11 3 HEAT-like repeat HEAT PF02985.17 KKK15524.1 - 2.6e-10 39.4 22.3 0.31 11.2 0.0 11.7 13 0 0 13 13 12 3 HEAT repeat Adaptin_N PF01602.15 KKK15524.1 - 9.9e-08 30.7 10.2 0.00046 18.6 2.6 4.7 2 2 0 2 2 2 2 Adaptin N terminal region CLASP_N PF12348.3 KKK15524.1 - 0.00019 20.8 1.2 0.96 8.7 0.0 4.7 4 0 0 4 4 4 1 CLASP N terminal MMS19_C PF12460.3 KKK15524.1 - 0.0052 15.5 0.1 0.0052 15.5 0.0 4.2 5 0 0 5 5 5 1 RNAPII transcription regulator C-terminal SH3_1 PF00018.23 KKK15525.1 - 5.6e-10 38.4 0.1 1.5e-09 37.1 0.1 1.8 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KKK15525.1 - 1.4e-09 37.2 0.0 2.7e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 KKK15525.1 - 6.3e-09 35.2 0.1 1.5e-08 34.1 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain Nop14 PF04147.7 KKK15525.1 - 1.5 6.6 23.8 3 5.6 16.5 1.4 1 0 0 1 1 1 0 Nop14-like family Chorismate_synt PF01264.16 KKK15526.1 - 5.7e-129 429.5 0.0 6.8e-129 429.2 0.0 1.0 1 0 0 1 1 1 1 Chorismate synthase BPL_LplA_LipB PF03099.14 KKK15528.1 - 1.8e-16 60.2 0.0 3.1e-16 59.5 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Formyl_trans_N PF00551.14 KKK15530.1 - 3.5e-21 75.5 0.1 2.4e-20 72.8 0.0 2.2 3 0 0 3 3 3 1 Formyl transferase Formyl_trans_C PF02911.13 KKK15530.1 - 0.0011 19.0 0.1 0.0034 17.4 0.1 1.9 1 1 0 1 1 1 1 Formyl transferase, C-terminal domain DUF1712 PF08217.6 KKK15531.1 - 4.3e-17 61.5 0.0 2.3e-15 55.8 0.0 2.1 2 0 0 2 2 2 2 Fungal domain of unknown function (DUF1712) Alg14 PF08660.6 KKK15532.1 - 3.1e-57 193.2 0.0 5e-57 192.5 0.0 1.3 1 1 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like DUF624 PF04854.9 KKK15532.1 - 0.017 14.9 0.2 0.11 12.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF624 adh_short PF00106.20 KKK15533.1 - 8.8e-26 90.7 0.9 1.1e-25 90.4 0.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KKK15533.1 - 9.7e-22 77.8 0.3 1.1e-21 77.6 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KKK15533.1 - 4.2e-11 42.8 0.6 6.1e-11 42.3 0.4 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KKK15533.1 - 0.0044 16.4 0.3 5.3 6.3 0.0 3.1 3 1 0 3 3 3 2 NAD dependent epimerase/dehydratase family Imm12 PF15589.1 KKK15533.1 - 0.053 13.2 0.1 0.49 10.1 0.0 2.2 2 0 0 2 2 2 0 Immunity protein 12 F5_F8_type_C PF00754.20 KKK15533.1 - 0.13 12.1 0.1 0.27 11.0 0.0 1.6 1 0 0 1 1 1 0 F5/8 type C domain Sugar_tr PF00083.19 KKK15534.1 - 0.00014 20.6 0.4 0.00015 20.4 0.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter Ima1_N PF09779.4 KKK15535.1 - 4.5e-45 153.3 1.9 4.5e-45 153.3 1.3 1.7 2 0 0 2 2 2 1 Ima1 N-terminal domain RNHCP PF12647.2 KKK15535.1 - 0.076 12.8 0.7 0.23 11.3 0.5 1.8 1 0 0 1 1 1 0 RNHCP domain DUF2264 PF10022.4 KKK15536.1 - 2.6e-134 447.4 0.0 3.2e-134 447.1 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2264) Sugar_tr PF00083.19 KKK15537.1 - 5.8e-104 348.1 20.3 6.6e-104 347.9 14.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KKK15537.1 - 2.2e-21 76.0 27.4 3e-21 75.5 19.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Fungal_trans_2 PF11951.3 KKK15539.1 - 1.3e-51 175.4 0.0 2.1e-51 174.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK15539.1 - 2e-05 24.4 3.8 4.8e-05 23.1 2.6 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF678 PF05077.7 KKK15539.1 - 0.15 12.0 2.1 0.35 10.8 1.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF678) Mannosyl_trans3 PF11051.3 KKK15540.1 - 3.2e-77 259.5 0.0 8.8e-77 258.0 0.0 1.6 1 1 0 1 1 1 1 Mannosyltransferase putative Kinesin PF00225.18 KKK15542.1 - 3.2e-90 302.2 0.0 3.2e-90 302.2 0.0 2.4 3 0 0 3 3 3 1 Kinesin motor domain CM_2 PF01817.16 KKK15543.1 - 1.6e-10 40.9 0.1 5.7e-06 26.3 0.0 3.2 2 1 0 2 2 2 2 Chorismate mutase type II BCIP PF13862.1 KKK15544.1 - 2.7e-75 252.1 0.0 3.7e-75 251.7 0.0 1.2 1 0 0 1 1 1 1 p21-C-terminal region-binding protein Sad1_UNC PF07738.8 KKK15545.1 - 1.5e-12 47.4 0.0 1.3e-06 28.2 0.0 2.7 3 0 0 3 3 3 2 Sad1 / UNC-like C-terminal WD40 PF00400.27 KKK15546.1 - 6.7e-38 127.2 9.9 8.1e-10 38.1 0.3 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 KKK15546.1 - 8.2e-08 30.8 10.8 0.0046 15.1 0.8 4.8 1 1 2 4 4 4 2 Nucleoporin Nup120/160 APG6 PF04111.7 KKK15546.1 - 0.0074 15.3 1.0 0.012 14.6 0.7 1.2 1 0 0 1 1 1 1 Autophagy protein Apg6 PQQ_2 PF13360.1 KKK15546.1 - 0.042 13.3 0.6 1 8.7 0.0 2.5 1 1 1 2 2 2 0 PQQ-like domain AAA_23 PF13476.1 KKK15546.1 - 0.43 10.8 1.7 0.7 10.1 1.2 1.2 1 0 0 1 1 1 0 AAA domain IncA PF04156.9 KKK15546.1 - 0.48 10.0 5.0 0.85 9.1 3.5 1.4 1 0 0 1 1 1 0 IncA protein Spc24 PF08286.6 KKK15546.1 - 0.65 9.6 4.1 0.25 11.0 0.8 1.9 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 HSP70 PF00012.15 KKK15548.1 - 0.0039 15.1 0.0 0.018 12.9 0.0 1.8 1 1 0 1 1 1 1 Hsp70 protein DDR PF08841.5 KKK15548.1 - 0.069 11.9 0.0 2.1 7.0 0.0 2.2 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain FKBP_C PF00254.23 KKK15550.1 - 2.5e-32 110.7 0.0 2.9e-32 110.5 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase IBR PF01485.16 KKK15553.1 - 3.7e-08 33.1 7.1 9.6e-07 28.5 1.6 4.5 5 0 0 5 5 5 3 IBR domain Lactonase PF10282.4 KKK15554.1 - 5e-20 71.8 0.1 6.1e-20 71.5 0.1 1.1 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller SGL PF08450.7 KKK15554.1 - 0.1 11.9 0.0 0.25 10.6 0.0 1.7 2 0 0 2 2 2 0 SMP-30/Gluconolaconase/LRE-like region Cation_efflux PF01545.16 KKK15556.1 - 2.2e-26 92.5 4.6 2.9e-26 92.2 3.2 1.1 1 0 0 1 1 1 1 Cation efflux family ATG16 PF08614.6 KKK15556.1 - 0.36 10.6 3.3 0.49 10.1 1.9 1.4 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF3237 PF11578.3 KKK15557.1 - 2e-51 173.2 0.0 2.2e-51 173.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) EMP24_GP25L PF01105.19 KKK15558.1 - 6.8e-48 162.8 0.6 8.1e-48 162.5 0.4 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD 14-3-3 PF00244.15 KKK15559.1 - 4.4e-11 42.3 0.4 8.7e-11 41.3 0.1 1.5 2 0 0 2 2 2 1 14-3-3 protein Metallophos PF00149.23 KKK15560.1 - 1.8e-09 37.2 0.6 5.7e-09 35.6 0.4 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase PAM2 PF07145.10 KKK15561.1 - 0.00031 20.0 9.1 0.077 12.5 0.0 4.7 5 0 0 5 5 5 3 Ataxin-2 C-terminal region Myb_DNA-bind_6 PF13921.1 KKK15562.1 - 8.1e-05 22.6 1.2 0.0075 16.3 0.2 2.7 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 KKK15562.1 - 0.00093 19.2 4.4 0.17 11.9 0.6 3.0 2 1 0 2 2 2 2 Myb-like DNA-binding domain Nucleoplasmin PF03066.10 KKK15562.1 - 0.0099 15.4 8.4 0.015 14.8 5.8 1.3 1 0 0 1 1 1 1 Nucleoplasmin RXT2_N PF08595.6 KKK15562.1 - 0.018 14.8 2.6 0.028 14.2 1.8 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal PBP1_TM PF14812.1 KKK15562.1 - 0.16 12.2 5.9 0.3 11.3 4.1 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Myc_N PF01056.13 KKK15562.1 - 0.18 10.9 4.8 0.24 10.5 3.3 1.2 1 0 0 1 1 1 0 Myc amino-terminal region CENP-B_dimeris PF09026.5 KKK15562.1 - 0.21 11.8 9.1 0.39 10.9 6.3 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Myb_DNA-bind_5 PF13873.1 KKK15562.1 - 0.23 11.3 2.9 3 7.8 0.0 2.6 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain NOA36 PF06524.7 KKK15562.1 - 0.27 10.4 4.7 0.36 10.0 3.3 1.1 1 0 0 1 1 1 0 NOA36 protein Glyco_hydro_17 PF00332.13 KKK15563.1 - 3.2e-25 88.8 0.6 2e-24 86.1 0.4 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 PGK PF00162.14 KKK15563.1 - 0.023 13.2 0.1 0.067 11.7 0.0 1.6 1 1 1 2 2 2 0 Phosphoglycerate kinase Lactamase_B PF00753.22 KKK15573.1 - 4.1e-09 36.3 0.9 5.2e-08 32.7 0.6 2.1 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KKK15573.1 - 0.00041 19.9 0.1 0.00063 19.3 0.1 1.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain ABC1 PF03109.11 KKK15574.1 - 1.2e-21 76.8 0.1 9.8e-21 73.9 0.0 2.3 2 0 0 2 2 2 1 ABC1 family APH PF01636.18 KKK15574.1 - 0.032 13.9 0.0 0.15 11.7 0.0 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family PBP PF01161.15 KKK15600.1 - 2.9e-11 43.4 0.0 4.2e-11 42.8 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein CBS PF00571.23 KKK15601.1 - 1.2e-22 79.4 4.2 1e-11 44.4 0.1 4.0 4 0 0 4 4 4 3 CBS domain Kinesin PF00225.18 KKK15604.1 - 3.4e-113 377.7 0.0 3.4e-113 377.7 0.0 1.9 3 0 0 3 3 3 1 Kinesin motor domain Bacillus_HBL PF05791.6 KKK15604.1 - 0.029 13.7 0.4 0.029 13.7 0.3 2.2 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) DUF1275 PF06912.6 KKK15605.1 - 5.4e-47 159.6 10.4 6.7e-47 159.3 7.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) Herpes_US9 PF06072.6 KKK15605.1 - 0.4 10.5 3.0 4.9 7.0 0.1 3.1 3 0 0 3 3 3 0 Alphaherpesvirus tegument protein US9 Apc13p PF05839.6 KKK15606.1 - 5.1e-18 64.8 0.0 1.3e-17 63.5 0.0 1.7 2 0 0 2 2 2 1 Apc13p protein CRAL_TRIO PF00650.15 KKK15607.1 - 3.7e-37 127.2 0.0 6.6e-37 126.4 0.0 1.4 2 0 0 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 KKK15607.1 - 5.5e-12 45.6 0.0 1.3e-11 44.4 0.0 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 KKK15607.1 - 0.00023 21.0 0.0 0.00035 20.5 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain IF-2B PF01008.12 KKK15608.1 - 4.9e-75 252.1 0.0 6.1e-75 251.8 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family Pol_alpha_B_N PF08418.5 KKK15609.1 - 1.6e-48 165.5 0.0 1.4e-24 86.9 0.0 2.2 1 1 1 2 2 2 2 DNA polymerase alpha subunit B N-terminal DNA_pol_E_B PF04042.11 KKK15609.1 - 9.4e-38 129.5 0.0 1.4e-37 129.0 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Ribosomal_L4 PF00573.17 KKK15610.1 - 2.7e-44 150.8 0.0 3.3e-44 150.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family BDV_P24 PF06595.6 KKK15610.1 - 0.014 15.2 0.0 0.024 14.4 0.0 1.4 1 0 0 1 1 1 0 Borna disease virus P24 protein ECH_C PF13766.1 KKK15611.1 - 4.5e-40 136.4 0.2 1e-39 135.3 0.1 1.6 1 0 0 1 1 1 1 2-enoyl-CoA Hydratase C-terminal region ECH PF00378.15 KKK15611.1 - 2e-24 86.0 0.0 5.1e-24 84.7 0.0 1.7 1 1 1 2 2 2 1 Enoyl-CoA hydratase/isomerase family FPN1 PF06963.7 KKK15612.1 - 1.4e-158 527.8 19.0 5.4e-158 525.9 13.0 1.8 2 0 0 2 2 2 1 Ferroportin1 (FPN1) Fungal_trans_2 PF11951.3 KKK15612.1 - 8.1e-12 44.4 0.0 1.6e-11 43.4 0.0 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Sulfatase PF00884.18 KKK15613.1 - 1.6e-70 237.7 0.0 2e-70 237.4 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Sulfatase_C PF14707.1 KKK15613.1 - 0.0045 17.2 0.2 0.13 12.5 0.1 2.5 1 1 0 1 1 1 1 C-terminal region of aryl-sulfatase bZIP_1 PF00170.16 KKK15614.1 - 3.1e-08 33.4 7.9 5.4e-08 32.6 5.5 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KKK15614.1 - 0.0033 17.2 8.3 0.0057 16.4 5.8 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 KKK15614.1 - 1.7 8.9 11.9 0.045 14.0 3.4 1.9 2 0 0 2 2 2 0 bZIP Maf transcription factor CAF-1_p150 PF11600.3 KKK15617.1 - 0.094 12.0 12.6 0.16 11.3 8.8 1.4 1 1 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DBINO PF13892.1 KKK15617.1 - 0.15 12.0 9.0 0.21 11.5 6.3 1.2 1 0 0 1 1 1 0 DNA-binding domain Rad60-SLD PF11976.3 KKK15618.1 - 4.8e-22 77.4 0.2 5.8e-22 77.1 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 KKK15618.1 - 4.7e-09 35.5 0.1 5.9e-09 35.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family SRP9-21 PF05486.7 KKK15618.1 - 0.16 11.6 0.3 0.26 11.0 0.2 1.4 1 1 0 1 1 1 0 Signal recognition particle 9 kDa protein (SRP9) APH PF01636.18 KKK15619.1 - 0.018 14.8 0.1 0.027 14.1 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family APH PF01636.18 KKK15620.1 - 0.056 13.1 0.3 0.06 13.0 0.2 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Nup84_Nup100 PF04121.8 KKK15621.1 - 1e-58 198.6 2.7 3.7e-52 176.9 0.0 2.8 3 1 0 3 3 3 2 Nuclear pore protein 84 / 107 CDP-OH_P_transf PF01066.16 KKK15622.1 - 2.3e-12 47.0 2.1 2.3e-12 47.0 1.5 1.7 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase PqiA PF04403.8 KKK15622.1 - 0.078 12.5 0.2 0.16 11.5 0.2 1.4 1 0 0 1 1 1 0 Paraquat-inducible protein A WSC PF01822.14 KKK15623.1 - 3e-15 55.9 8.4 3e-15 55.9 5.8 2.3 2 0 0 2 2 2 1 WSC domain SKG6 PF08693.5 KKK15623.1 - 1.6e-10 40.1 0.3 1.6e-10 40.1 0.2 1.9 2 0 0 2 2 2 1 Transmembrane alpha-helix domain Alpha_GJ PF03229.8 KKK15623.1 - 0.00095 19.5 3.8 0.0016 18.7 2.6 1.4 1 0 0 1 1 1 1 Alphavirus glycoprotein J TrbL PF04610.9 KKK15623.1 - 0.16 11.6 1.8 0.25 11.0 1.3 1.2 1 0 0 1 1 1 0 TrbL/VirB6 plasmid conjugal transfer protein Pex14_N PF04695.8 KKK15623.1 - 0.29 11.1 3.8 0.67 10.0 2.7 1.6 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF515 PF04415.7 KKK15623.1 - 5.8 5.0 14.3 8 4.5 9.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Abhydrolase_6 PF12697.2 KKK15624.1 - 1.6e-22 80.5 0.0 2.3e-22 80.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KKK15624.1 - 2.5e-07 30.5 0.0 6.4e-07 29.1 0.0 1.7 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KKK15624.1 - 4.5e-07 29.7 0.0 1.1e-06 28.4 0.0 1.7 1 1 1 2 2 2 1 Alpha/beta hydrolase family Thioesterase PF00975.15 KKK15624.1 - 0.00081 19.6 0.1 0.00094 19.4 0.1 1.3 1 1 0 1 1 1 1 Thioesterase domain Abhydrolase_8 PF06259.7 KKK15624.1 - 0.081 12.4 0.1 0.76 9.2 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase DUF604 PF04646.7 KKK15625.1 - 2.7e-12 46.4 0.2 6.1e-12 45.2 0.1 1.6 2 0 0 2 2 2 1 Protein of unknown function, DUF604 tRNA-synt_2b PF00587.20 KKK15626.1 - 5.1e-44 149.8 0.0 9.3e-44 149.0 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 KKK15626.1 - 2.3e-17 62.6 0.2 4.8e-17 61.6 0.2 1.6 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.9 KKK15626.1 - 1.2e-13 50.6 0.0 2.5e-13 49.6 0.0 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.16 KKK15626.1 - 8.1e-05 22.3 0.0 0.00016 21.4 0.0 1.5 1 0 0 1 1 1 1 TGS domain Gar1 PF04410.9 KKK15627.1 - 1.4e-43 147.9 0.2 2.4e-43 147.2 0.0 1.4 1 1 0 1 1 1 1 Gar1/Naf1 RNA binding region Acyl-CoA_dh_1 PF00441.19 KKK15631.1 - 1.5e-41 141.9 0.4 2.3e-41 141.4 0.3 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 KKK15631.1 - 7.6e-21 73.3 0.2 1.4e-20 72.5 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Cyt-b5 PF00173.23 KKK15631.1 - 2.3e-18 65.7 0.4 4.1e-18 64.9 0.3 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_N PF02771.11 KKK15631.1 - 3.4e-18 66.2 0.0 7.6e-18 65.1 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 KKK15631.1 - 2e-08 34.5 0.0 3.4e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl_transf_3 PF01757.17 KKK15632.1 - 1.7e-32 112.6 36.7 2.9e-32 111.8 25.5 1.4 1 1 0 1 1 1 1 Acyltransferase family CTD PF12815.2 KKK15633.1 - 4.1e-26 91.8 56.9 7e-24 84.6 25.1 3.7 2 1 1 3 3 3 3 Spt5 C-terminal nonapeptide repeat binding Spt4 Spt5-NGN PF03439.8 KKK15633.1 - 1.2e-25 89.0 0.0 2e-25 88.3 0.0 1.4 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section Spt5_N PF11942.3 KKK15633.1 - 1e-18 67.6 11.7 1e-18 67.6 8.1 4.5 2 1 0 2 2 2 1 Spt5 transcription elongation factor, acidic N-terminal KOW PF00467.24 KKK15633.1 - 4.6e-13 48.3 9.2 0.00044 19.8 0.4 4.8 5 0 0 5 5 5 3 KOW motif mRNA_triPase PF02940.10 KKK15634.1 - 2.7e-59 200.5 0.0 5.7e-59 199.4 0.0 1.6 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain Peptidase_C12 PF01088.16 KKK15638.1 - 2.6e-62 209.7 0.0 3.9e-62 209.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 I-set PF07679.11 KKK15639.1 - 0.0098 15.7 0.2 1.3 8.9 0.0 4.0 5 0 0 5 5 5 1 Immunoglobulin I-set domain OTU PF02338.14 KKK15640.1 - 1.6e-13 51.3 0.0 2.8e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 KKK15640.1 - 0.041 13.2 0.0 0.087 12.1 0.0 1.4 1 1 0 1 1 1 0 Peptidase C65 Otubain Pkinase PF00069.20 KKK15641.1 - 6.7e-42 143.4 0.0 2.3e-36 125.2 0.0 3.1 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KKK15641.1 - 1.2e-09 37.6 0.0 0.00032 19.8 0.0 3.1 2 1 1 3 3 3 2 Protein tyrosine kinase APH PF01636.18 KKK15641.1 - 0.011 15.4 0.4 1 9.0 0.0 2.6 2 1 1 3 3 3 0 Phosphotransferase enzyme family Cnd1_N PF12922.2 KKK15642.1 - 4.4e-59 198.9 0.0 1.1e-58 197.6 0.0 1.8 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1, N-term Cnd1 PF12717.2 KKK15642.1 - 4.6e-55 186.2 3.3 6.3e-50 169.4 0.0 3.3 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 KKK15642.1 - 2.9e-13 49.8 5.3 2.1e-06 27.9 0.0 5.2 4 2 1 5 5 5 2 HEAT repeats HEAT PF02985.17 KKK15642.1 - 1.6e-08 33.8 8.3 0.2 11.8 0.0 6.1 6 0 0 6 6 6 3 HEAT repeat Adaptin_N PF01602.15 KKK15642.1 - 7e-07 27.9 7.5 0.017 13.4 0.2 4.1 3 2 0 3 3 3 3 Adaptin N terminal region HEAT_EZ PF13513.1 KKK15642.1 - 4.2e-06 27.0 7.5 0.19 12.2 0.0 6.3 6 0 0 6 6 6 2 HEAT-like repeat DUF2435 PF10363.4 KKK15642.1 - 0.0021 17.8 0.0 1.3 8.9 0.0 3.5 2 1 1 3 3 3 1 Protein of unknown function (DUF2435) Cnd3 PF12719.2 KKK15642.1 - 0.036 13.0 5.5 0.066 12.1 0.8 3.4 3 1 0 3 3 3 0 Nuclear condensing complex subunits, C-term domain Cohesin_HEAT PF12765.2 KKK15642.1 - 0.054 13.4 3.9 13 5.8 0.0 4.3 4 0 0 4 4 4 0 HEAT repeat associated with sister chromatid cohesion mono-CXXC PF15626.1 KKK15642.1 - 1.6 8.7 3.9 34 4.4 0.9 2.7 2 0 0 2 2 2 0 single CXXC unit Oxysterol_BP PF01237.13 KKK15643.1 - 3.1e-54 183.8 0.0 8.7e-54 182.3 0.0 1.7 1 1 0 1 1 1 1 Oxysterol-binding protein DUF2413 PF10310.4 KKK15643.1 - 0.041 12.7 0.0 0.057 12.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Abhydrolase_6 PF12697.2 KKK15644.1 - 1.2e-09 38.4 0.3 1.7e-09 37.9 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KKK15644.1 - 1.3e-05 24.9 0.0 2.7e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 KKK15644.1 - 0.18 11.2 0.0 0.28 10.5 0.0 1.2 1 0 0 1 1 1 0 Putative esterase Ion_trans_2 PF07885.11 KKK15645.1 - 1.1e-24 85.8 23.0 8.4e-15 54.2 6.3 3.5 3 1 0 3 3 3 2 Ion channel Toxin_49 PF15529.1 KKK15645.1 - 0.031 14.2 1.2 3.9 7.4 0.1 2.4 1 1 1 2 2 2 0 Putative toxin 49 DUF3180 PF11377.3 KKK15645.1 - 2 8.2 8.4 0.82 9.5 0.2 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF3180) Ion_trans PF00520.26 KKK15645.1 - 5.8 6.1 23.5 1.3 8.2 6.5 3.5 2 2 1 3 3 3 0 Ion transport protein Bromodomain PF00439.20 KKK15647.1 - 1.6e-36 124.0 4.5 1.7e-19 69.5 0.1 2.6 2 0 0 2 2 2 2 Bromodomain BAH PF01426.13 KKK15647.1 - 1.5e-17 63.4 1.3 3e-17 62.4 0.9 1.5 1 0 0 1 1 1 1 BAH domain DUF1353 PF07087.6 KKK15647.1 - 0.085 12.3 0.0 0.41 10.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1353) Nucleoplasmin PF03066.10 KKK15647.1 - 0.31 10.5 9.6 0.8 9.2 6.7 1.7 1 0 0 1 1 1 0 Nucleoplasmin CENP-B_dimeris PF09026.5 KKK15647.1 - 3.6 7.8 13.5 14 5.9 9.4 2.0 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Histone PF00125.19 KKK15648.1 - 2.9e-22 78.5 0.3 4.1e-22 78.0 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KKK15648.1 - 0.00039 20.4 0.0 0.00039 20.4 0.0 1.9 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 KKK15648.1 - 0.00041 20.5 0.0 0.00068 19.8 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A RP-C PF03428.8 KKK15648.1 - 0.017 14.5 0.1 0.024 14.0 0.0 1.2 1 0 0 1 1 1 0 Replication protein C N-terminal domain Peptidase_C54 PF03416.14 KKK15649.1 - 4.1e-94 314.8 0.0 5e-94 314.5 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C54 Complex1_LYR PF05347.10 KKK15650.1 - 1.7e-09 37.2 0.3 2.7e-09 36.6 0.2 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KKK15650.1 - 5.6e-07 29.6 0.2 8e-07 29.1 0.1 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Histone PF00125.19 KKK15651.1 - 8.2e-26 89.9 0.0 1e-25 89.6 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KKK15651.1 - 1.2e-05 25.2 0.0 1.6e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone PCMT PF01135.14 KKK15652.1 - 5.7e-55 186.0 0.0 1.7e-54 184.5 0.0 1.6 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.2 KKK15652.1 - 1.5e-10 41.6 0.0 2.1e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KKK15652.1 - 4e-09 36.2 0.0 5.2e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KKK15652.1 - 6.1e-06 26.5 0.0 9.5e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KKK15652.1 - 6.2e-06 26.0 0.0 8.8e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 KKK15652.1 - 2.8e-05 23.8 0.0 4.1e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KKK15652.1 - 3.9e-05 23.6 0.0 5.8e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KKK15652.1 - 0.002 18.5 0.0 0.0032 17.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KKK15652.1 - 0.005 17.3 0.0 0.01 16.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 KKK15652.1 - 0.0055 16.0 0.0 0.0079 15.5 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW MTS PF05175.9 KKK15652.1 - 0.016 14.5 0.0 0.028 13.7 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase small domain PrmA PF06325.8 KKK15652.1 - 0.032 13.3 0.0 0.044 12.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.13 KKK15652.1 - 0.042 12.9 0.0 0.06 12.4 0.0 1.1 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family GCD14 PF08704.5 KKK15652.1 - 0.069 12.6 0.0 0.094 12.2 0.0 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit RrnaAD PF00398.15 KKK15652.1 - 0.076 12.0 0.0 0.098 11.6 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_3 PF01596.12 KKK15652.1 - 0.12 11.4 0.0 0.15 11.0 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase 2-oxoacid_dh PF00198.18 KKK15653.1 - 3.3e-80 268.6 0.0 5.4e-80 267.9 0.0 1.3 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 KKK15653.1 - 1.5e-19 69.3 2.0 2.7e-19 68.5 1.4 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme HlyD_2 PF12700.2 KKK15653.1 - 2e-05 23.9 2.4 0.00044 19.4 0.3 2.5 1 1 1 2 2 2 1 HlyD family secretion protein Biotin_lipoyl_2 PF13533.1 KKK15653.1 - 0.0039 16.8 0.4 0.13 11.9 0.1 2.4 1 1 1 2 2 2 1 Biotin-lipoyl like RnfC_N PF13375.1 KKK15653.1 - 0.0046 16.6 0.2 0.031 13.9 0.1 2.3 1 1 0 1 1 1 1 RnfC Barrel sandwich hybrid domain GCV_H PF01597.14 KKK15653.1 - 0.016 14.9 0.4 0.032 13.8 0.3 1.5 1 0 0 1 1 1 0 Glycine cleavage H-protein HlyD_3 PF13437.1 KKK15653.1 - 0.023 15.0 0.2 0.91 9.9 0.1 2.3 1 1 1 2 2 2 0 HlyD family secretion protein DUF2360 PF10152.4 KKK15653.1 - 0.68 10.2 8.4 1.3 9.3 5.8 1.4 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) FAP PF07174.6 KKK15653.1 - 3.2 6.9 16.6 5.1 6.3 11.5 1.2 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) Helicase_C_2 PF13307.1 KKK15654.1 - 1.5e-51 174.6 0.0 4.1e-51 173.2 0.0 1.7 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.10 KKK15654.1 - 4.5e-47 159.6 0.0 7.8e-47 158.9 0.0 1.4 1 0 0 1 1 1 1 DEAD_2 Ribosomal_L18e PF00828.14 KKK15654.1 - 1.7e-32 112.5 0.0 4.9e-32 111.0 0.0 1.9 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 DEAD PF00270.24 KKK15654.1 - 0.0031 17.0 0.0 0.7 9.3 0.0 2.4 2 0 0 2 2 2 2 DEAD/DEAH box helicase Dor1 PF04124.7 KKK15654.1 - 0.0091 14.5 0.7 0.016 13.6 0.5 1.3 1 0 0 1 1 1 1 Dor1-like family Sel1 PF08238.7 KKK15655.1 - 6.8e-08 32.9 6.3 0.024 15.2 0.1 3.6 3 0 0 3 3 3 3 Sel1 repeat TPR_1 PF00515.23 KKK15655.1 - 3.8e-05 23.0 0.0 0.00025 20.5 0.0 2.4 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.1 KKK15655.1 - 6.8e-05 22.4 1.7 7.8e-05 22.2 0.1 1.9 2 0 0 2 2 2 1 TPR repeat TPR_16 PF13432.1 KKK15655.1 - 0.0039 17.8 0.2 0.14 12.8 0.0 2.8 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 KKK15655.1 - 0.0048 17.4 0.2 0.048 14.3 0.0 2.8 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 KKK15655.1 - 0.0063 16.3 0.0 0.0063 16.3 0.0 2.8 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 KKK15655.1 - 0.053 13.4 0.5 0.33 10.9 0.0 2.4 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 KKK15655.1 - 0.059 13.8 0.9 0.61 10.6 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 KKK15655.1 - 0.065 13.0 0.0 0.49 10.3 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Cys_Met_Meta_PP PF01053.15 KKK15656.1 - 3.5e-33 114.4 0.0 4.6e-33 114.0 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Nrap PF03813.9 KKK15657.1 - 0 1205.4 0.0 0 1205.1 0.0 1.0 1 0 0 1 1 1 1 Nrap protein MRP-L20 PF12824.2 KKK15658.1 - 1.8e-64 216.6 8.3 2e-64 216.4 5.8 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Peptidase_M20 PF01546.23 KKK15659.1 - 4.1e-30 104.7 0.0 6.8e-30 103.9 0.0 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 KKK15659.1 - 1.7e-13 50.2 0.0 3.1e-13 49.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain SMC_N PF02463.14 KKK15660.1 - 4.9e-21 74.9 20.8 8.8e-13 47.9 0.1 3.0 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 KKK15660.1 - 8.3e-20 71.9 2.6 8.3e-20 71.9 1.8 4.7 2 2 1 4 4 4 1 AAA domain AAA_21 PF13304.1 KKK15660.1 - 1.2e-09 38.5 1.4 1.7e-05 24.9 0.2 2.5 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 KKK15660.1 - 0.00011 21.6 0.0 0.00024 20.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.22 KKK15660.1 - 0.1 12.8 0.1 0.1 12.8 0.1 6.1 3 2 0 3 3 3 0 ABC transporter AAA_13 PF13166.1 KKK15660.1 - 2.1 6.7 72.3 0.18 10.2 3.3 5.3 3 2 1 5 5 5 0 AAA domain Reo_sigmaC PF04582.7 KKK15660.1 - 2.7 7.0 13.6 1.7 7.7 0.8 3.7 3 1 1 4 4 4 0 Reovirus sigma C capsid protein AAA_15 PF13175.1 KKK15660.1 - 4.8 6.1 22.3 0.023 13.7 7.3 3.0 2 2 0 2 2 2 0 AAA ATPase domain TPR_MLP1_2 PF07926.7 KKK15660.1 - 9.3 6.0 83.5 0.66 9.7 2.2 6.5 4 1 1 6 6 6 0 TPR/MLP1/MLP2-like protein Mito_carr PF00153.22 KKK15662.1 - 2.1e-54 181.1 4.5 4.1e-21 74.4 0.1 4.0 4 0 0 4 4 4 4 Mitochondrial carrier protein DEAD PF00270.24 KKK15663.1 - 1.7e-40 138.3 0.0 2.3e-40 137.8 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KKK15663.1 - 8.3e-24 83.2 0.1 1.6e-23 82.3 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KKK15663.1 - 0.082 12.7 0.0 0.82 9.4 0.0 2.1 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit DnaJ PF00226.26 KKK15664.1 - 1.7e-25 88.5 2.2 1.7e-25 88.5 1.5 2.7 3 0 0 3 3 3 1 DnaJ domain TPR_11 PF13414.1 KKK15664.1 - 4.4e-17 61.4 1.8 3.7e-08 32.8 0.0 5.9 5 2 3 8 8 8 5 TPR repeat TPR_1 PF00515.23 KKK15664.1 - 1.9e-14 52.5 0.1 2.2e-06 27.0 0.0 6.5 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_2 PF07719.12 KKK15664.1 - 1.7e-13 49.3 2.1 0.0005 19.7 0.0 7.1 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_14 PF13428.1 KKK15664.1 - 4.6e-12 45.4 6.5 0.039 14.5 0.5 6.7 3 3 4 7 7 7 3 Tetratricopeptide repeat TPR_9 PF13371.1 KKK15664.1 - 1.9e-11 43.6 3.6 3.2e-05 23.7 0.4 4.6 2 1 2 4 4 4 4 Tetratricopeptide repeat TPR_16 PF13432.1 KKK15664.1 - 8.6e-11 42.2 12.1 0.00028 21.4 1.2 5.2 5 2 2 7 7 7 4 Tetratricopeptide repeat TPR_19 PF14559.1 KKK15664.1 - 3.5e-10 40.0 2.0 9.4e-05 22.6 0.0 3.9 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.1 KKK15664.1 - 8.7e-06 25.1 0.0 0.086 12.6 0.0 5.8 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_12 PF13424.1 KKK15664.1 - 4.9e-05 23.1 6.3 0.043 13.7 0.2 4.5 4 2 1 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.1 KKK15664.1 - 8.1e-05 22.5 3.6 0.55 10.5 0.0 4.9 5 0 0 5 5 4 1 Tetratricopeptide repeat Apc3 PF12895.2 KKK15664.1 - 0.00073 19.6 7.3 0.071 13.2 0.1 4.7 5 1 1 6 6 6 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 KKK15664.1 - 0.0018 18.5 10.6 5 7.7 0.0 7.2 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_7 PF13176.1 KKK15664.1 - 0.0067 16.1 0.6 6.2 6.8 0.0 4.5 3 1 1 4 4 4 1 Tetratricopeptide repeat RF-1 PF00472.15 KKK15665.1 - 2e-34 117.8 1.4 2e-34 117.8 1.0 1.6 2 0 0 2 2 2 1 RF-1 domain PCRF PF03462.13 KKK15665.1 - 5.9e-29 100.1 0.0 1.1e-27 96.0 0.0 2.4 2 0 0 2 2 2 1 PCRF domain DUF3322 PF11795.3 KKK15665.1 - 0.019 14.5 1.7 0.49 10.0 0.2 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria N-term (DUF3322) Aldo_ket_red PF00248.16 KKK15682.1 - 6.8e-35 120.2 0.0 1.6e-23 82.9 0.0 2.1 1 1 1 2 2 2 2 Aldo/keto reductase family MFS_1 PF07690.11 KKK15684.1 - 4.9e-31 107.7 29.3 6.4e-31 107.3 20.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KKK15684.1 - 3.4e-07 29.2 8.3 3.4e-07 29.2 5.8 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_2 PF13347.1 KKK15684.1 - 1.4e-05 23.7 10.2 1.4e-05 23.7 7.1 2.2 2 0 0 2 2 2 1 MFS/sugar transport protein LacY_symp PF01306.14 KKK15684.1 - 0.018 13.6 0.9 0.018 13.6 0.6 1.8 2 0 0 2 2 2 0 LacY proton/sugar symporter OATP PF03137.15 KKK15684.1 - 0.037 12.1 4.5 0.097 10.7 3.1 1.8 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DUF1705 PF08019.7 KKK15684.1 - 0.079 12.4 1.6 0.38 10.2 0.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1705) Acetyltransf_10 PF13673.1 KKK15685.1 - 0.054 13.6 0.1 0.12 12.5 0.1 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain AMP-binding PF00501.23 KKK15686.1 - 1.1e-75 254.6 0.0 2e-75 253.7 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 KKK15686.1 - 7.4e-40 136.4 0.0 1.6e-39 135.3 0.0 1.6 1 0 0 1 1 1 1 Male sterility protein Condensation PF00668.15 KKK15686.1 - 1.2e-35 122.8 1.1 1.9e-35 122.1 0.0 1.9 3 0 0 3 3 3 1 Condensation domain Epimerase PF01370.16 KKK15686.1 - 4.5e-11 42.6 0.0 9.8e-11 41.5 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 KKK15686.1 - 5e-09 36.2 0.0 2.8e-08 33.9 0.0 2.3 2 0 0 2 2 2 1 Phosphopantetheine attachment site AMP-binding_C PF13193.1 KKK15686.1 - 2.1e-05 25.3 0.9 2.1e-05 25.3 0.6 3.7 4 0 0 4 4 4 1 AMP-binding enzyme C-terminal domain 3Beta_HSD PF01073.14 KKK15686.1 - 0.00018 20.3 0.0 0.00034 19.4 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 KKK15686.1 - 0.00054 20.2 0.0 0.0013 19.0 0.0 1.7 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.12 KKK15686.1 - 0.03 13.2 0.0 0.18 10.6 0.0 2.3 1 1 0 1 1 1 0 RmlD substrate binding domain 2OG-FeII_Oxy PF03171.15 KKK15687.1 - 1.4e-12 47.7 0.0 2.4e-12 46.9 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 KKK15687.1 - 1.9e-06 28.4 0.0 3e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal DUF2746 PF10874.3 KKK15687.1 - 0.062 13.4 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2746) Methyltransf_23 PF13489.1 KKK15696.1 - 6.7e-16 58.4 0.0 8.3e-16 58.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KKK15696.1 - 6.2e-13 49.0 0.0 1.2e-12 48.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KKK15696.1 - 5.8e-12 46.1 0.0 9.1e-12 45.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KKK15696.1 - 6.4e-12 45.3 0.0 9.1e-12 44.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KKK15696.1 - 1.2e-10 41.5 0.0 2.5e-10 40.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KKK15696.1 - 2.4e-10 40.7 0.0 3.8e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KKK15696.1 - 2e-05 23.8 0.1 4.6e-05 22.6 0.0 1.6 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 KKK15696.1 - 0.00084 19.3 0.0 0.0016 18.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain tRNA_U5-meth_tr PF05958.6 KKK15696.1 - 0.0017 17.1 0.0 0.0024 16.6 0.0 1.2 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase MTS PF05175.9 KKK15696.1 - 0.0024 17.2 0.0 0.0043 16.4 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase small domain CheR PF01739.13 KKK15696.1 - 0.088 12.0 0.1 1.9 7.7 0.0 2.2 1 1 0 2 2 2 0 CheR methyltransferase, SAM binding domain NAD_binding_10 PF13460.1 KKK15697.1 - 1.1e-18 67.9 0.0 1.6e-18 67.4 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 KKK15697.1 - 2.4e-16 59.7 0.0 3e-16 59.3 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 KKK15697.1 - 2e-15 56.8 0.0 5.2e-15 55.5 0.0 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KKK15697.1 - 6.9e-13 47.9 0.1 1.3e-12 47.0 0.1 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 KKK15697.1 - 1.2e-07 30.9 0.0 2.1e-06 26.8 0.0 2.3 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 KKK15697.1 - 5.3e-06 25.5 0.5 8.5e-05 21.5 0.3 2.3 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.20 KKK15697.1 - 9.8e-05 22.3 0.0 0.0015 18.5 0.0 2.2 1 1 0 1 1 1 1 short chain dehydrogenase Saccharop_dh PF03435.13 KKK15697.1 - 0.0056 15.7 0.0 0.0085 15.1 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase KR PF08659.5 KKK15697.1 - 0.0065 16.1 0.0 3.1 7.4 0.0 2.3 2 0 0 2 2 2 2 KR domain Polysacc_synt_2 PF02719.10 KKK15697.1 - 0.011 14.6 0.0 0.017 14.0 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DDE_Tnp_1_3 PF13612.1 KKK15697.1 - 0.021 14.5 0.0 0.082 12.6 0.0 1.9 2 0 0 2 2 2 0 Transposase DDE domain WW PF00397.21 KKK15698.1 - 0.00015 21.5 3.3 0.00015 21.5 2.3 1.9 2 0 0 2 2 2 1 WW domain CoA_transf_3 PF02515.12 KKK15699.1 - 3.2e-51 173.3 0.0 4e-51 172.9 0.0 1.1 1 0 0 1 1 1 1 CoA-transferase family III Mito_carr PF00153.22 KKK15708.1 - 5e-68 224.8 3.7 2.2e-22 78.5 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF4137 PF13593.1 KKK15709.1 - 1.9e-82 276.8 20.8 3.9e-65 220.0 5.8 2.0 2 0 0 2 2 2 2 SBF-like CPA transporter family (DUF4137) SBF PF01758.11 KKK15709.1 - 9.3e-08 31.6 6.9 9.3e-08 31.6 4.8 2.1 2 0 0 2 2 2 1 Sodium Bile acid symporter family ADH_N PF08240.7 KKK15757.1 - 2.1e-11 43.5 0.0 3.9e-11 42.6 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KKK15757.1 - 3.3e-07 29.9 0.0 5.9e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Aminotran_5 PF00266.14 KKK15758.1 - 2.9e-29 101.9 0.0 8.8e-19 67.4 0.0 2.0 1 1 1 2 2 2 2 Aminotransferase class-V Lipase_3 PF01764.20 KKK15760.1 - 6.8e-19 67.8 0.0 1.3e-18 66.9 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 KKK15760.1 - 0.021 14.5 0.0 0.036 13.8 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family PGAP1 PF07819.8 KKK15760.1 - 0.038 13.5 0.0 0.085 12.4 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein DUF676 PF05057.9 KKK15760.1 - 0.095 11.9 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Pkinase PF00069.20 KKK15761.1 - 1.1e-69 234.5 0.0 1.4e-69 234.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK15761.1 - 1.7e-34 119.0 0.0 2.5e-34 118.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KKK15761.1 - 0.0015 17.5 0.0 0.0023 16.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KKK15761.1 - 0.015 14.3 0.0 0.029 13.4 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 KKK15761.1 - 0.023 14.0 0.0 0.051 12.9 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL NmrA PF05368.8 KKK15762.1 - 2.2e-17 63.0 0.0 3e-17 62.6 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KKK15762.1 - 1.1e-12 48.3 0.0 6.9e-12 45.7 0.0 2.2 2 1 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 KKK15762.1 - 3.6e-08 33.1 0.1 9.3e-08 31.7 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family KR PF08659.5 KKK15762.1 - 2.2e-05 24.2 0.1 3e-05 23.7 0.1 1.2 1 0 0 1 1 1 1 KR domain Saccharop_dh PF03435.13 KKK15762.1 - 3.1e-05 23.1 0.1 4.2e-05 22.6 0.1 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_4 PF07993.7 KKK15762.1 - 0.00017 20.6 0.0 0.00025 20.0 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein adh_short PF00106.20 KKK15762.1 - 0.00089 19.2 0.1 0.0015 18.5 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase 3Beta_HSD PF01073.14 KKK15762.1 - 0.0032 16.2 0.1 0.0053 15.4 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Shikimate_DH PF01488.15 KKK15762.1 - 0.0064 16.5 0.0 0.011 15.7 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase RmlD_sub_bind PF04321.12 KKK15762.1 - 0.0076 15.1 0.2 0.014 14.2 0.1 1.5 2 0 0 2 2 2 1 RmlD substrate binding domain TrkA_N PF02254.13 KKK15762.1 - 0.025 14.6 0.1 0.11 12.4 0.0 2.0 2 0 0 2 2 2 0 TrkA-N domain Polysacc_synt_2 PF02719.10 KKK15762.1 - 0.037 12.9 0.3 0.074 11.9 0.2 1.4 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein Semialdhyde_dh PF01118.19 KKK15762.1 - 0.037 14.3 0.1 0.09 13.0 0.0 1.6 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain B12-binding PF02310.14 KKK15762.1 - 0.085 12.7 0.1 0.28 11.0 0.1 1.8 2 0 0 2 2 2 0 B12 binding domain ApbA PF02558.11 KKK15762.1 - 0.09 12.2 0.0 0.17 11.3 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DapB_N PF01113.15 KKK15762.1 - 0.16 11.8 0.6 0.33 10.8 0.3 1.6 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Zn_clus PF00172.13 KKK15763.1 - 0.0052 16.6 5.6 0.035 14.0 3.9 2.2 1 1 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DnaJ_CXXCXGXG PF00684.14 KKK15763.1 - 0.14 12.2 2.3 0.22 11.5 1.6 1.4 1 0 0 1 1 1 0 DnaJ central domain PRK PF00485.13 KKK15764.1 - 2.3e-08 33.8 0.0 3e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_17 PF13207.1 KKK15764.1 - 1.2e-07 32.5 0.1 2.7e-07 31.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KKK15764.1 - 9.9e-07 29.1 0.1 3.8e-06 27.2 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KKK15764.1 - 2.8e-05 24.0 1.0 0.012 15.5 0.1 2.7 2 1 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 KKK15764.1 - 5.1e-05 22.4 0.6 0.00015 20.9 0.1 1.9 2 0 0 2 2 2 1 Zeta toxin Thymidylate_kin PF02223.12 KKK15764.1 - 0.0014 18.0 0.2 1.3 8.3 0.0 2.2 2 0 0 2 2 2 2 Thymidylate kinase SRP54 PF00448.17 KKK15764.1 - 0.0014 18.1 0.0 0.0021 17.5 0.0 1.2 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_19 PF13245.1 KKK15764.1 - 0.0026 17.4 0.1 0.0057 16.3 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA PF00004.24 KKK15764.1 - 0.0029 17.7 0.1 0.0071 16.5 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KKK15764.1 - 0.0059 16.7 0.0 0.014 15.4 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KKK15764.1 - 0.0071 16.3 0.8 0.019 14.9 0.6 1.9 1 1 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.17 KKK15764.1 - 0.0089 14.9 0.0 0.014 14.3 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain AAA_30 PF13604.1 KKK15764.1 - 0.017 14.7 0.6 0.036 13.6 0.1 1.7 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.15 KKK15764.1 - 0.021 14.5 0.0 0.12 12.0 0.0 2.0 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_11 PF13086.1 KKK15764.1 - 0.025 14.1 0.0 0.071 12.6 0.0 1.6 1 1 0 1 1 1 0 AAA domain ArgK PF03308.11 KKK15764.1 - 0.025 13.3 0.1 0.036 12.8 0.0 1.2 1 0 0 1 1 1 0 ArgK protein 6PF2K PF01591.13 KKK15764.1 - 0.051 12.6 0.0 0.09 11.8 0.0 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase IF-2B PF01008.12 KKK15765.1 - 5.1e-08 32.2 0.1 0.0016 17.5 0.0 2.3 2 0 0 2 2 2 2 Initiation factor 2 subunit family NUDIX PF00293.23 KKK15765.1 - 9.2e-06 25.3 0.1 1.8e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain Fungal_trans PF04082.13 KKK15766.1 - 6.9e-19 67.7 0.1 2e-18 66.2 0.0 1.7 1 1 1 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK15766.1 - 5.1e-08 32.6 6.7 8.4e-08 31.9 4.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Methyltransf_23 PF13489.1 KKK15767.1 - 1.7e-19 70.1 0.0 2.3e-19 69.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KKK15767.1 - 1.4e-16 60.7 0.0 2.3e-16 60.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KKK15767.1 - 6.9e-13 48.9 0.0 1.9e-12 47.4 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KKK15767.1 - 1e-12 48.6 0.0 1.5e-12 48.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KKK15767.1 - 2.1e-11 43.6 0.0 8.3e-05 22.2 0.0 2.1 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.1 KKK15767.1 - 5.9e-06 26.5 0.0 9.8e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KKK15767.1 - 1.6e-05 24.9 0.5 4.2e-05 23.5 0.1 1.9 2 1 0 2 2 1 1 Methyltransferase domain DREV PF05219.7 KKK15767.1 - 0.00076 18.4 0.0 0.00096 18.0 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase NodS PF05401.6 KKK15767.1 - 0.0017 17.8 0.0 0.041 13.2 0.0 2.2 2 0 0 2 2 2 1 Nodulation protein S (NodS) Ubie_methyltran PF01209.13 KKK15767.1 - 0.0023 17.1 0.0 0.21 10.6 0.0 2.2 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family RrnaAD PF00398.15 KKK15767.1 - 0.0023 17.0 0.0 0.0034 16.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase MTS PF05175.9 KKK15767.1 - 0.0056 16.0 0.0 0.0096 15.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_16 PF10294.4 KKK15767.1 - 0.014 14.8 0.0 0.047 13.1 0.0 1.8 2 0 0 2 2 2 0 Putative methyltransferase PCMT PF01135.14 KKK15767.1 - 0.095 12.2 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.8 KKK15767.1 - 0.14 11.2 0.0 0.19 10.7 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_2 PF00891.13 KKK15769.1 - 3.4e-16 59.1 0.0 4.1e-16 58.9 0.0 1.0 1 0 0 1 1 1 1 O-methyltransferase Peptidase_M41 PF01434.13 KKK15771.1 - 1.5e-73 246.7 0.0 1.8e-73 246.5 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M41 DUF1295 PF06966.7 KKK15772.1 - 2.2e-42 144.9 6.2 2.8e-42 144.6 4.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Topoisom_bac PF01131.15 KKK15773.1 - 2.9e-88 296.4 0.0 4.6e-88 295.7 0.0 1.3 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.17 KKK15773.1 - 2.8e-19 68.9 0.0 5.7e-19 67.9 0.0 1.5 1 0 0 1 1 1 1 Toprim domain DUF4149 PF13664.1 KKK15774.1 - 6.6e-20 71.0 4.5 2.4e-19 69.2 1.4 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) Ras PF00071.17 KKK15790.1 - 1.4e-59 200.0 0.2 1.7e-59 199.8 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KKK15790.1 - 7.2e-19 68.4 0.0 1e-18 67.9 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KKK15790.1 - 1.3e-08 34.3 0.0 1.4e-08 34.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KKK15790.1 - 1.2e-07 31.4 0.1 5.6e-07 29.1 0.1 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 KKK15790.1 - 0.0017 17.6 0.0 0.0027 16.9 0.0 1.4 1 1 0 1 1 1 1 Ferrous iron transport protein B MMR_HSR1 PF01926.18 KKK15790.1 - 0.0021 17.9 0.0 0.0026 17.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF2075 PF09848.4 KKK15790.1 - 0.028 13.3 0.1 0.64 8.9 0.1 2.0 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Gtr1_RagA PF04670.7 KKK15790.1 - 0.033 13.3 0.1 0.039 13.0 0.1 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region IstB_IS21 PF01695.12 KKK15790.1 - 0.053 12.9 0.6 0.72 9.2 0.1 2.2 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF258 PF03193.11 KKK15790.1 - 0.064 12.4 0.1 0.21 10.7 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function, DUF258 DUF2277 PF10041.4 KKK15790.1 - 0.11 12.4 0.0 0.48 10.4 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2277) ATP_bind_1 PF03029.12 KKK15790.1 - 0.15 11.5 1.7 1.9 7.9 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein CbiA PF01656.18 KKK15790.1 - 0.15 11.4 0.1 1.3 8.3 0.0 2.0 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain Glyco_hydro_16 PF00722.16 KKK15791.1 - 1.3e-41 141.8 5.9 1.3e-41 141.8 4.1 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 Mif2_N PF15624.1 KKK15807.1 - 4.1e-34 118.1 7.4 4.1e-34 118.1 5.1 4.8 2 1 2 4 4 4 1 Kinetochore CENP-C fungal homologue, Mif2, N-terminal CENP-C_C PF11699.3 KKK15807.1 - 1.3e-24 85.9 1.3 2.1e-22 78.8 0.9 2.5 1 1 0 1 1 1 1 Mif2/CENP-C like CAP_GLY PF01302.20 KKK15808.1 - 1.9e-28 97.9 0.0 2.9e-28 97.3 0.0 1.3 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.1 KKK15808.1 - 7.2e-17 61.4 0.0 1.3e-16 60.5 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin-like domain ubiquitin PF00240.18 KKK15808.1 - 7.4e-05 22.0 0.0 0.00017 20.9 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin family Aldedh PF00171.17 KKK15810.1 - 1.7e-33 115.6 0.0 1.9e-33 115.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF849 PF05853.7 KKK15810.1 - 0.076 11.8 0.0 0.086 11.7 0.0 1.1 1 0 0 1 1 1 0 Prokaryotic protein of unknown function (DUF849) Amino_oxidase PF01593.19 KKK15811.1 - 3.7e-53 181.2 0.1 8e-35 120.7 0.0 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Ribonuc_L-PSP PF01042.16 KKK15811.1 - 1.1e-17 63.8 0.1 2.7e-17 62.6 0.1 1.6 1 0 0 1 1 1 1 Endoribonuclease L-PSP NAD_binding_8 PF13450.1 KKK15811.1 - 2.7e-13 49.7 0.2 6.4e-13 48.5 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KKK15811.1 - 5e-09 35.5 0.7 7.9e-09 34.8 0.5 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 KKK15811.1 - 4.2e-08 32.5 1.3 1.2e-07 31.0 0.5 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 KKK15811.1 - 6.8e-07 28.6 0.3 1.2e-06 27.7 0.2 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.14 KKK15811.1 - 2.1e-06 27.0 0.3 6e-06 25.5 0.2 1.6 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.2 KKK15811.1 - 4.8e-06 25.9 0.8 7.2e-06 25.3 0.5 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KKK15811.1 - 8.9e-06 25.7 0.1 7.2e-05 22.7 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KKK15811.1 - 1.3e-05 25.3 0.6 2.3e-05 24.5 0.2 1.6 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KKK15811.1 - 1.6e-05 24.0 0.5 2.8e-05 23.1 0.3 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.9 KKK15811.1 - 0.00038 19.0 0.3 0.00069 18.2 0.2 1.4 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.17 KKK15811.1 - 0.0016 17.3 0.3 0.0025 16.7 0.2 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.22 KKK15811.1 - 0.0064 16.8 0.3 0.015 15.7 0.2 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 KKK15811.1 - 0.13 11.8 0.4 0.25 10.9 0.1 1.5 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Sugar_tr PF00083.19 KKK15816.1 - 5.2e-95 318.6 28.5 6e-95 318.4 19.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KKK15816.1 - 1.7e-27 96.0 57.4 9.3e-25 87.0 20.1 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KKK15816.1 - 0.0002 19.9 1.8 0.0002 19.9 1.2 3.4 3 1 1 4 4 4 2 MFS/sugar transport protein Gp_dh_N PF00044.19 KKK15817.1 - 6.3e-49 165.8 0.1 9.9e-49 165.1 0.0 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Gp_dh_C PF02800.15 KKK15817.1 - 2.2e-30 105.1 0.2 3.6e-30 104.4 0.2 1.4 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 2-Hacid_dh_C PF02826.14 KKK15817.1 - 0.0018 17.4 0.0 0.0032 16.6 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DapB_N PF01113.15 KKK15817.1 - 0.0023 17.8 0.0 0.0039 17.0 0.0 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus COesterase PF00135.23 KKK15819.1 - 3.8e-71 240.4 0.0 5.4e-71 239.9 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KKK15819.1 - 4.7e-07 29.5 0.1 2.2e-06 27.3 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold WD40 PF00400.27 KKK15821.1 - 8.8e-25 85.6 23.7 4.8e-08 32.5 0.0 6.9 7 0 0 7 7 7 6 WD domain, G-beta repeat eIF2A PF08662.6 KKK15821.1 - 0.00014 21.6 0.0 0.0016 18.1 0.0 2.0 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A DUF1014 PF06244.7 KKK15822.1 - 1.3e-24 86.6 6.0 2.8e-24 85.6 4.2 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1014) DUF1510 PF07423.6 KKK15822.1 - 9.3 5.5 14.6 16 4.7 10.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Pkinase PF00069.20 KKK15823.1 - 9e-64 215.1 0.0 1.5e-63 214.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK15823.1 - 1e-35 123.0 0.0 1e-30 106.6 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KKK15823.1 - 1.9e-05 23.7 0.0 0.012 14.5 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 KKK15823.1 - 0.00046 19.9 0.1 0.0016 18.2 0.1 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 KKK15823.1 - 0.00053 19.3 0.0 0.0011 18.3 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 KKK15823.1 - 0.018 14.1 0.2 0.053 12.5 0.0 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 KKK15823.1 - 0.037 13.3 0.0 0.071 12.4 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL DUF2404 PF10296.4 KKK15824.1 - 0.00011 22.2 0.0 0.00093 19.2 0.0 2.1 2 0 0 2 2 2 1 Putative integral membrane protein conserved region (DUF2404) GWT1 PF06423.7 KKK15825.1 - 3.2e-38 130.8 3.3 8.8e-38 129.4 2.3 1.8 1 0 0 1 1 1 1 GWT1 bZIP_1 PF00170.16 KKK15826.1 - 0.00056 19.8 10.2 0.0021 17.9 7.1 1.9 1 1 0 1 1 1 1 bZIP transcription factor UDG PF03167.14 KKK15826.1 - 0.081 12.3 0.3 0.081 12.3 0.2 1.7 2 0 0 2 2 2 0 Uracil DNA glycosylase superfamily bZIP_2 PF07716.10 KKK15826.1 - 0.081 12.7 13.4 0.26 11.1 5.1 2.3 1 1 1 2 2 2 0 Basic region leucine zipper Zip PF02535.17 KKK15826.1 - 0.89 8.4 4.4 1.2 8.0 3.0 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Acyl-CoA_dh_1 PF00441.19 KKK15827.1 - 1.3e-39 135.6 8.1 2.2e-39 134.9 5.6 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 KKK15827.1 - 6e-27 94.4 1.4 1.5e-26 93.2 0.0 2.3 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 KKK15827.1 - 2.3e-18 65.4 0.5 1.1e-17 63.3 0.0 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 KKK15827.1 - 1.6e-15 57.5 4.9 3e-15 56.6 3.4 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Metallophos PF00149.23 KKK15827.1 - 0.00035 20.0 1.4 0.0025 17.2 1.0 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KKK15827.1 - 0.0085 15.9 0.1 0.032 14.0 0.1 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain HpaB_N PF11794.3 KKK15827.1 - 0.05 12.9 0.1 0.16 11.3 0.1 1.8 1 1 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal Senescence PF06911.7 KKK15828.1 - 9e-47 159.0 2.3 1.3e-46 158.5 1.6 1.2 1 0 0 1 1 1 1 Senescence-associated protein Atx10homo_assoc PF09759.4 KKK15832.1 - 2.3e-33 113.9 0.3 9.4e-33 112.0 0.0 2.1 2 0 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain TFIIA PF03153.8 KKK15832.1 - 0.7 9.7 7.3 1.2 8.9 5.0 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zf-RING_2 PF13639.1 KKK15833.1 - 1e-08 34.8 2.8 2e-08 33.8 2.0 1.5 1 0 0 1 1 1 1 Ring finger domain Pyridox_oxidase PF01243.15 KKK15833.1 - 1e-07 31.8 0.0 4.1e-05 23.4 0.0 3.1 2 1 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase zf-rbx1 PF12678.2 KKK15833.1 - 2.1e-05 24.5 0.3 4.7e-05 23.4 0.2 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger FAD_binding_6 PF00970.19 KKK15833.1 - 0.00028 20.9 0.0 0.0017 18.4 0.0 2.1 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain zf-Apc11 PF12861.2 KKK15833.1 - 0.0016 18.2 0.4 0.003 17.3 0.3 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.1 KKK15833.1 - 0.02 14.9 1.9 0.046 13.7 1.3 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Kdo PF06293.9 KKK15834.1 - 4.6e-05 22.5 0.0 0.00011 21.3 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KKK15834.1 - 0.00075 19.2 5.7 0.0017 18.1 0.0 3.1 2 1 1 3 3 3 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KKK15834.1 - 0.003 17.1 0.3 0.0085 15.6 0.0 1.8 2 0 0 2 2 2 1 Choline/ethanolamine kinase Pkinase PF00069.20 KKK15834.1 - 0.0084 15.2 0.0 0.021 14.0 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain tRNA-synt_2 PF00152.15 KKK15835.1 - 3.1e-90 302.3 0.2 4.9e-90 301.6 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 KKK15835.1 - 3e-13 49.4 0.1 6.6e-13 48.3 0.1 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 KKK15835.1 - 1.2e-05 24.6 0.0 0.014 14.5 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) Dynamin_N PF00350.18 KKK15836.1 - 2.3e-24 86.1 0.0 5.4e-24 84.9 0.0 1.7 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 KKK15836.1 - 2.3e-21 75.8 0.0 2.3e-16 59.4 0.0 2.3 2 0 0 2 2 2 2 Dynamin central region GED PF02212.13 KKK15836.1 - 0.00013 21.7 0.2 0.00043 20.1 0.1 1.9 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 KKK15836.1 - 0.00048 20.0 0.0 0.014 15.3 0.0 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KKK15836.1 - 0.0041 17.6 0.0 0.013 15.9 0.0 1.9 1 0 0 1 1 1 1 Miro-like protein IIGP PF05049.8 KKK15836.1 - 0.036 12.8 0.0 4 6.1 0.0 2.3 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) CM_1 PF07736.6 KKK15836.1 - 0.037 14.1 0.0 0.88 9.6 0.0 2.5 2 0 0 2 2 2 0 Chorismate mutase type I Cpn60_TCP1 PF00118.19 KKK15837.1 - 1.2e-147 492.5 2.2 1.3e-147 492.3 1.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Chromo PF00385.19 KKK15838.1 - 7.6e-10 38.3 0.9 5.6e-09 35.5 0.1 2.4 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.14 KKK15838.1 - 7.9e-10 38.4 0.0 4.1e-08 32.9 0.0 2.2 2 0 0 2 2 2 1 Chromo shadow domain ORC6 PF05460.8 KKK15838.1 - 0.00072 18.7 2.5 0.00093 18.3 1.7 1.2 1 0 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) Tox-REase-7 PF15649.1 KKK15838.1 - 0.077 13.1 0.4 0.077 13.1 0.3 2.0 2 0 0 2 2 2 0 Restriction endonuclease fold toxin 7 Pap_E4 PF02711.9 KKK15838.1 - 0.51 11.1 4.1 1 10.2 2.8 1.4 1 0 0 1 1 1 0 E4 protein Rap1_C PF11626.3 KKK15839.1 - 2.4e-25 88.2 0.0 5.3e-25 87.1 0.0 1.6 1 0 0 1 1 1 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_2 PF08914.6 KKK15839.1 - 9.1e-21 73.4 0.9 2.4e-20 72.1 0.6 1.7 1 0 0 1 1 1 1 Rap1 Myb domain Rap1-DNA-bind PF09197.5 KKK15839.1 - 3.6e-07 30.6 0.1 1.5e-06 28.6 0.0 2.1 2 1 0 2 2 2 1 Rap1, DNA-binding NTP_transferase PF00483.18 KKK15841.1 - 1.6e-29 102.9 0.0 2.2e-29 102.4 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.19 KKK15841.1 - 6.9e-08 31.6 9.5 6.1e-07 28.6 0.2 4.0 2 1 1 3 3 3 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 KKK15841.1 - 1.1e-07 32.0 0.0 1.9e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.14 KKK15841.1 - 0.0028 17.2 0.0 0.005 16.3 0.0 1.4 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Glycos_transf_2 PF00535.21 KKK15841.1 - 0.028 14.0 0.0 0.051 13.2 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 DUF2968 PF11180.3 KKK15841.1 - 0.055 12.8 0.1 0.088 12.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) CENP-L PF13092.1 KKK15854.1 - 1.5e-48 164.6 0.0 2.4e-48 163.9 0.0 1.3 1 0 0 1 1 1 1 Kinetochore complex Sim4 subunit Fta1 F-box-like PF12937.2 KKK15855.1 - 0.00018 21.1 0.1 0.00018 21.1 0.1 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KKK15855.1 - 0.00018 21.0 0.0 0.0005 19.6 0.0 1.8 1 0 0 1 1 1 1 F-box domain PRANC PF09372.5 KKK15855.1 - 0.013 15.4 0.0 0.2 11.6 0.0 2.5 2 0 0 2 2 2 0 PRANC domain FYVE PF01363.16 KKK15856.1 - 4.8e-22 77.6 23.4 7.9e-16 57.7 4.3 3.0 3 0 0 3 3 3 2 FYVE zinc finger zf-Di19 PF05605.7 KKK15856.1 - 0.0088 16.1 12.0 0.067 13.3 0.0 2.8 3 0 0 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding zf-AN1 PF01428.11 KKK15856.1 - 0.016 15.0 6.7 0.016 15.0 4.7 3.7 3 1 1 4 4 4 0 AN1-like Zinc finger Rbsn PF11464.3 KKK15856.1 - 0.02 14.4 0.4 0.075 12.6 0.1 2.1 2 0 0 2 2 2 0 Rabenosyn Rab binding domain zf-C2H2_4 PF13894.1 KKK15856.1 - 0.66 10.4 16.0 3.3 8.2 0.0 4.0 3 0 0 3 3 3 0 C2H2-type zinc finger IBR PF01485.16 KKK15856.1 - 4.2 7.3 19.5 0.18 11.7 2.3 3.2 4 0 0 4 4 4 0 IBR domain PKD_channel PF08016.7 KKK15857.1 - 1e-05 24.1 22.5 0.0001 20.9 15.0 2.3 1 1 0 1 1 1 1 Polycystin cation channel MADF_DNA_bdg PF10545.4 KKK15857.1 - 0.17 12.0 0.7 0.58 10.3 0.5 1.9 1 1 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Hydrolase PF00702.21 KKK15858.1 - 2.9e-22 80.1 0.0 1.3e-21 78.0 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KKK15858.1 - 2.5e-21 76.7 0.0 4.5e-21 75.8 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 KKK15858.1 - 2.9e-20 72.3 0.7 1e-19 70.4 0.0 2.2 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase_like2 PF13246.1 KKK15858.1 - 5.5e-05 23.0 0.0 0.00097 19.0 0.0 2.5 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KKK15858.1 - 0.0027 17.3 0.1 0.012 15.2 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 KKK15858.1 - 0.062 12.5 0.3 0.3 10.3 0.0 2.2 3 0 0 3 3 3 0 Sucrose-6F-phosphate phosphohydrolase GLTP PF08718.6 KKK15859.1 - 2.5e-45 154.1 0.0 3.4e-45 153.7 0.0 1.2 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) BMC PF00936.14 KKK15859.1 - 0.018 14.6 0.0 0.033 13.8 0.0 1.4 1 0 0 1 1 1 0 BMC domain PH_4 PF15404.1 KKK15860.1 - 1.1e-56 191.3 1.7 2e-55 187.2 0.1 3.2 3 0 0 3 3 3 1 Pleckstrin homology domain Spo7_2_N PF15407.1 KKK15860.1 - 5.6e-21 73.7 0.5 1.5e-20 72.4 0.4 1.8 1 0 0 1 1 1 1 Sporulation protein family 7 PH PF00169.24 KKK15860.1 - 8.7e-10 38.7 4.4 9.4e-06 25.7 0.0 3.9 4 0 0 4 4 4 2 PH domain PH_6 PF15406.1 KKK15860.1 - 0.0024 17.9 0.1 4.3 7.4 0.0 2.9 2 0 0 2 2 2 2 Pleckstrin homology domain DUF1992 PF09350.5 KKK15860.1 - 0.0069 16.1 1.7 0.1 12.4 0.1 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF1992) Macro PF01661.16 KKK15861.1 - 1.7e-39 134.3 0.1 2.5e-39 133.8 0.1 1.3 1 0 0 1 1 1 1 Macro domain Peptidase_S24 PF00717.18 KKK15862.1 - 1.8e-05 24.2 0.0 7.9e-05 22.2 0.0 2.0 1 1 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.4 KKK15862.1 - 0.00079 18.9 0.0 0.18 11.3 0.0 2.3 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 GATA PF00320.22 KKK15863.1 - 9.5e-15 53.6 5.2 1.7e-14 52.8 3.6 1.4 1 0 0 1 1 1 1 GATA zinc finger zf-RING_3 PF14369.1 KKK15863.1 - 0.25 11.3 1.9 0.52 10.3 1.3 1.5 1 0 0 1 1 1 0 zinc-finger adh_short PF00106.20 KKK15864.1 - 1.6e-05 24.8 0.0 2.8e-05 24.0 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase Band_7 PF01145.20 KKK15865.1 - 9.5e-28 97.3 2.8 1.8e-27 96.4 2.0 1.4 1 0 0 1 1 1 1 SPFH domain / Band 7 family EIF_2_alpha PF07541.7 KKK15866.1 - 1.9e-39 133.9 0.0 4.9e-39 132.5 0.0 1.7 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.18 KKK15866.1 - 2.1e-12 46.9 0.5 4.4e-12 45.9 0.4 1.6 1 0 0 1 1 1 1 S1 RNA binding domain Sulfate_transp PF00916.15 KKK15867.1 - 1.5e-50 171.7 5.1 1.8e-50 171.5 2.6 1.8 1 1 1 2 2 2 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 KKK15867.1 - 2.2e-27 94.5 4.5 2.2e-27 94.5 3.1 2.4 2 0 0 2 2 2 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 KKK15867.1 - 6.9e-16 57.7 0.0 1.2e-15 56.9 0.0 1.4 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.1 KKK15867.1 - 5.4e-05 23.1 0.0 0.00022 21.1 0.0 2.1 2 1 0 2 2 2 1 STAS domain Gram_pos_anchor PF00746.16 KKK15867.1 - 0.57 10.0 5.4 0.49 10.2 0.7 3.1 2 0 0 2 2 2 0 Gram positive anchor GTP_EFTU PF00009.22 KKK15869.1 - 6.2e-33 113.8 0.0 2.7e-32 111.7 0.0 2.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 KKK15869.1 - 2.3e-18 66.0 0.1 6.7e-18 64.5 0.1 1.8 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 KKK15869.1 - 7.6e-12 45.1 3.9 9.7e-10 38.4 0.0 3.5 3 0 0 3 3 3 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KKK15869.1 - 6.1e-06 26.1 0.0 2.7e-05 24.0 0.0 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.12 KKK15869.1 - 0.0063 16.0 0.0 0.015 14.8 0.0 1.8 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein GTP_EFTU_D4 PF14578.1 KKK15869.1 - 0.0064 16.1 0.1 0.023 14.3 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu domain 4 Miro PF08477.8 KKK15869.1 - 0.0086 16.5 0.5 0.068 13.6 0.0 2.8 2 0 0 2 2 2 1 Miro-like protein Rhodanese PF00581.15 KKK15870.1 - 3.1e-11 43.5 0.0 5.6e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain Peripla_BP_6 PF13458.1 KKK15870.1 - 0.027 13.8 0.0 0.041 13.2 0.0 1.2 1 0 0 1 1 1 0 Periplasmic binding protein Yip1 PF04893.12 KKK15871.1 - 2.1e-14 53.4 15.9 2.9e-14 52.9 11.0 1.3 1 0 0 1 1 1 1 Yip1 domain Mem_trans PF03547.13 KKK15871.1 - 0.033 12.4 0.3 0.09 11.0 0.2 1.8 1 1 0 1 1 1 0 Membrane transport protein RabGAP-TBC PF00566.13 KKK15872.1 - 4.1e-25 88.5 0.2 5.8e-25 88.0 0.1 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain CaKB PF03185.10 KKK15872.1 - 0.033 13.5 0.1 0.067 12.5 0.1 1.4 1 0 0 1 1 1 0 Calcium-activated potassium channel, beta subunit MMS1_N PF10433.4 KKK15873.1 - 6.8e-148 492.9 0.0 1.5e-146 488.5 0.0 2.2 2 0 0 2 2 2 2 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.10 KKK15873.1 - 6.9e-10 38.5 0.0 4.4e-09 35.8 0.0 2.0 2 0 0 2 2 2 1 CPSF A subunit region PQQ_3 PF13570.1 KKK15873.1 - 0.18 12.1 0.1 7.6 6.9 0.0 3.5 3 0 0 3 3 3 0 PQQ-like domain p450 PF00067.17 KKK15874.1 - 1.3e-56 192.0 0.0 1.8e-56 191.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 NIF PF03031.13 KKK15886.1 - 1.2e-40 138.7 0.1 1.7e-40 138.2 0.1 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD_2 PF13419.1 KKK15886.1 - 0.067 13.4 0.3 0.23 11.6 0.0 2.0 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase JAB PF01398.16 KKK15887.1 - 3.3e-35 120.2 0.0 6.9e-35 119.2 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 KKK15887.1 - 1.4e-26 92.8 3.3 2.4e-26 92.0 2.3 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.1 KKK15887.1 - 5.1e-09 35.6 0.0 8.9e-09 34.8 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UCR_14kD PF02271.11 KKK15887.1 - 0.02 14.6 0.5 0.044 13.5 0.2 1.7 1 1 1 2 2 2 0 Ubiquinol-cytochrome C reductase complex 14kD subunit Ribosomal_L14 PF00238.14 KKK15889.1 - 5.8e-34 116.4 0.0 6.5e-34 116.3 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Hist_deacetyl PF00850.14 KKK15890.1 - 1.7e-78 264.0 0.0 2.9e-78 263.3 0.0 1.4 1 0 0 1 1 1 1 Histone deacetylase domain adh_short_C2 PF13561.1 KKK15897.1 - 1.4e-27 97.0 0.0 1.8e-27 96.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KKK15897.1 - 4.2e-23 82.0 0.3 7.1e-23 81.3 0.2 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KKK15897.1 - 9.5e-13 48.1 0.1 1.6e-12 47.4 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KKK15897.1 - 0.0021 17.5 0.2 0.0052 16.2 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1752 PF08550.5 KKK15898.1 - 0.0094 15.5 0.1 0.023 14.2 0.1 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) CPSase_L_D2 PF02786.12 KKK15900.1 - 1e-74 250.4 0.0 1.5e-74 249.8 0.0 1.2 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.14 KKK15900.1 - 6.1e-36 122.6 0.0 1.4e-35 121.4 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain CPSase_L_chain PF00289.17 KKK15900.1 - 2.9e-33 114.2 0.0 6.3e-33 113.1 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_lipoyl PF00364.17 KKK15900.1 - 1.2e-18 66.4 1.4 1.1e-17 63.4 0.6 2.7 2 0 0 2 2 2 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 KKK15900.1 - 6.2e-18 65.1 0.0 1.4e-17 64.0 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 KKK15900.1 - 1.3e-11 43.8 0.0 2.5e-11 42.9 0.0 1.4 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 KKK15900.1 - 6.7e-11 41.9 0.0 1.4e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 KKK15900.1 - 3.9e-08 32.8 0.0 7.1e-08 31.9 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.1 KKK15900.1 - 2.2e-06 27.2 0.0 0.0078 15.8 0.0 2.8 1 1 1 2 2 2 2 Biotin-lipoyl like ATP-grasp_3 PF02655.9 KKK15900.1 - 2.4e-05 24.2 0.0 5.3e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.14 KKK15900.1 - 0.0011 18.5 0.1 0.002 17.7 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain RimK PF08443.6 KKK15900.1 - 0.0028 17.1 0.0 0.013 14.9 0.0 2.0 2 0 0 2 2 2 1 RimK-like ATP-grasp domain HlyD_3 PF13437.1 KKK15900.1 - 0.0063 16.8 0.0 2.9 8.2 0.0 2.8 2 0 0 2 2 2 1 HlyD family secretion protein ATPgrasp_ST PF14397.1 KKK15900.1 - 0.022 13.8 0.0 0.053 12.5 0.0 1.6 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp GCV_H PF01597.14 KKK15900.1 - 0.045 13.4 0.1 0.11 12.1 0.1 1.6 1 0 0 1 1 1 0 Glycine cleavage H-protein HlyD PF00529.15 KKK15900.1 - 0.12 11.6 0.4 11 5.1 0.0 2.5 1 1 1 2 2 2 0 HlyD family secretion protein Carboxyl_trans PF01039.17 KKK15901.1 - 3.5e-133 444.5 0.1 2.5e-131 438.4 0.0 2.1 1 1 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.6 KKK15901.1 - 0.037 13.2 0.1 0.68 9.0 0.0 2.2 2 0 0 2 2 2 0 Malonate decarboxylase gamma subunit (MdcE) Acyl-CoA_dh_1 PF00441.19 KKK15902.1 - 4.4e-40 137.2 1.0 9.7e-40 136.1 0.7 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 KKK15902.1 - 3.8e-32 111.2 0.2 7.5e-32 110.2 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 KKK15902.1 - 3.9e-21 74.3 0.4 8.4e-21 73.2 0.3 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 KKK15902.1 - 8.5e-14 51.9 0.2 1.7e-13 50.9 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.3 KKK15902.1 - 0.0073 15.7 0.3 0.047 13.0 0.2 2.1 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal DUF3988 PF13149.1 KKK15902.1 - 0.056 12.9 0.0 0.083 12.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3988) DDOST_48kD PF03345.9 KKK15903.1 - 4.6e-172 572.3 0.0 5.2e-172 572.1 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta Abhydro_lipase PF04083.11 KKK15905.1 - 1.5e-22 78.6 0.1 5.2e-22 76.9 0.0 1.9 2 0 0 2 2 2 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.15 KKK15905.1 - 7.3e-20 71.5 0.0 1.1e-19 70.8 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KKK15905.1 - 4.9e-07 29.8 0.0 7.9e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KKK15905.1 - 5.2e-05 23.0 0.0 0.00042 20.0 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 KKK15905.1 - 0.023 14.1 0.0 2.2 7.6 0.0 2.1 2 0 0 2 2 2 0 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.11 KKK15905.1 - 0.13 11.7 0.0 6.9 6.0 0.0 2.3 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Pet191_N PF10203.4 KKK15906.1 - 5.9e-17 61.4 0.5 7.5e-17 61.1 0.4 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 Methyltransf_2 PF00891.13 KKK15907.1 - 1.1e-28 100.0 0.0 1.8e-28 99.3 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase ketoacyl-synt PF00109.21 KKK15908.1 - 3.5e-71 239.6 0.0 6.9e-71 238.6 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 KKK15908.1 - 6e-38 130.9 0.2 1.6e-37 129.5 0.1 1.7 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 KKK15908.1 - 4.3e-35 120.1 3.4 9e-35 119.0 0.8 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.20 KKK15908.1 - 4.1e-08 33.3 0.4 1.1e-07 32.0 0.3 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 KKK15908.1 - 0.008 15.1 0.1 0.014 14.3 0.1 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Sulfotransfer_3 PF13469.1 KKK15910.1 - 0.058 14.3 0.0 0.12 13.2 0.0 1.4 1 1 0 1 1 1 0 Sulfotransferase family p450 PF00067.17 KKK15911.1 - 1.4e-22 79.8 0.1 2e-22 79.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 DUF3991 PF13154.1 KKK15911.1 - 0.01 15.9 0.1 0.043 14.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3991) Glyco_hydro_75 PF07335.6 KKK15912.1 - 2.6e-42 144.3 0.0 3.9e-42 143.7 0.0 1.3 1 0 0 1 1 1 1 Fungal chitosanase of glycosyl hydrolase group 75 Ras PF00071.17 KKK15913.1 - 1.3e-51 174.1 0.0 1.6e-51 173.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KKK15913.1 - 8.6e-21 74.6 0.0 1.3e-20 74.0 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KKK15913.1 - 6.7e-10 38.4 0.0 8.2e-10 38.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KKK15913.1 - 2.4e-06 27.1 0.0 2.1e-05 24.0 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KKK15913.1 - 7.5e-06 25.8 0.0 1.3e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 KKK15913.1 - 0.0033 17.5 0.6 0.036 14.2 0.2 2.4 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KKK15913.1 - 0.035 14.0 1.6 0.7 9.8 1.1 2.3 1 1 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.1 KKK15913.1 - 0.13 11.6 0.1 0.39 10.0 0.1 1.9 1 1 0 1 1 1 0 AAA domain Acetyltransf_1 PF00583.19 KKK15914.1 - 2e-11 43.7 0.2 3.2e-11 43.0 0.1 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 KKK15914.1 - 3.4e-08 33.1 0.0 5e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 KKK15914.1 - 2.1e-07 31.0 0.0 2.5e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KKK15914.1 - 2.9e-06 27.3 0.1 4.1e-06 26.8 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KKK15914.1 - 0.00024 21.0 0.1 0.00031 20.6 0.1 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.1 KKK15914.1 - 0.00067 19.6 0.0 0.00089 19.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF3749 PF12568.3 KKK15914.1 - 0.00073 19.1 0.1 0.0008 18.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 KKK15914.1 - 0.0019 18.0 0.0 0.003 17.4 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase He_PIG PF05345.7 KKK15915.1 - 1e-14 54.2 10.0 0.00015 21.7 0.0 4.9 4 0 0 4 4 4 4 Putative Ig domain CUE PF02845.11 KKK15916.1 - 1.5e-10 40.2 0.0 2.5e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 CUE domain MOZART1 PF12554.3 KKK15917.1 - 1.3e-19 69.3 2.3 1.5e-15 56.4 0.2 2.2 2 0 0 2 2 2 2 Mitotic-spindle organizing gamma-tubulin ring associated SRP54_N PF02881.14 KKK15917.1 - 0.034 14.2 0.2 0.093 12.8 0.0 1.7 2 0 0 2 2 2 0 SRP54-type protein, helical bundle domain PITH PF06201.8 KKK15918.1 - 4e-46 156.5 0.0 4.9e-46 156.2 0.0 1.1 1 0 0 1 1 1 1 PITH domain NicO PF03824.11 KKK15918.1 - 1.6 8.0 3.6 2.1 7.5 2.5 1.1 1 0 0 1 1 1 0 High-affinity nickel-transport protein OB_NTP_bind PF07717.11 KKK15919.1 - 1.7e-22 79.3 0.0 3.4e-22 78.4 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 KKK15919.1 - 2.2e-21 75.7 0.0 4.2e-21 74.8 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 KKK15919.1 - 5.2e-12 45.4 0.0 1.2e-11 44.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 KKK15919.1 - 1.7e-05 24.9 0.0 3.9e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain DEAD PF00270.24 KKK15919.1 - 2.2e-05 24.0 0.0 4.5e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase T2SE PF00437.15 KKK15919.1 - 0.0074 15.2 0.1 0.03 13.2 0.0 2.0 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_30 PF13604.1 KKK15919.1 - 0.0075 15.8 0.0 0.013 15.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KKK15919.1 - 0.0094 15.8 0.1 3.2 7.6 0.0 2.6 1 1 1 2 2 2 1 AAA domain AAA_19 PF13245.1 KKK15919.1 - 0.023 14.4 0.0 0.062 13.0 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain cobW PF02492.14 KKK15919.1 - 0.029 13.8 0.0 0.086 12.2 0.0 1.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.1 KKK15919.1 - 0.097 12.9 0.0 0.26 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 KKK15919.1 - 0.58 9.2 2.9 0.57 9.2 0.1 2.2 2 1 1 3 3 3 0 Zeta toxin Snf7 PF03357.16 KKK15920.1 - 7.4e-36 123.0 3.3 1.1e-35 122.4 2.3 1.3 1 0 0 1 1 1 1 Snf7 MR_MLE_N PF02746.11 KKK15920.1 - 0.034 14.1 0.1 0.26 11.2 0.0 2.2 2 0 0 2 2 2 0 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain AAA PF00004.24 KKK15921.1 - 1.6e-89 296.9 0.0 2.7e-44 150.5 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KKK15921.1 - 2e-14 53.8 0.1 0.0034 17.5 0.0 5.8 2 2 2 4 4 4 2 AAA domain AAA_16 PF13191.1 KKK15921.1 - 5.8e-14 52.4 2.1 5e-06 26.6 0.0 4.5 3 2 2 5 5 5 2 AAA ATPase domain RuvB_N PF05496.7 KKK15921.1 - 1.2e-13 50.6 0.0 1.3e-06 27.6 0.0 2.3 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 KKK15921.1 - 3.9e-11 43.8 0.0 3.5e-06 27.8 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA_5 PF07728.9 KKK15921.1 - 5.2e-11 42.4 0.3 0.0011 18.7 0.1 3.8 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 KKK15921.1 - 6e-11 42.5 0.0 9.8e-05 22.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 KKK15921.1 - 1.5e-10 41.1 0.0 6.1e-05 22.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.1 KKK15921.1 - 1.8e-10 40.7 0.0 0.00032 20.5 0.0 3.0 3 0 0 3 3 3 2 AAA domain Zeta_toxin PF06414.7 KKK15921.1 - 2.4e-09 36.5 0.0 0.0019 17.3 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin TIP49 PF06068.8 KKK15921.1 - 6.7e-09 34.9 0.0 7.6e-05 21.5 0.0 2.3 2 0 0 2 2 2 2 TIP49 C-terminus AAA_19 PF13245.1 KKK15921.1 - 2.2e-08 33.7 0.1 0.0096 15.6 0.0 3.5 3 0 0 3 3 3 2 Part of AAA domain RNA_helicase PF00910.17 KKK15921.1 - 9.1e-08 32.2 0.0 0.0076 16.4 0.0 2.7 2 1 0 2 2 2 2 RNA helicase IstB_IS21 PF01695.12 KKK15921.1 - 1.3e-07 31.2 0.2 0.013 14.8 0.0 2.7 2 1 0 2 2 2 2 IstB-like ATP binding protein AAA_28 PF13521.1 KKK15921.1 - 1.4e-07 31.5 0.0 0.0057 16.6 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_25 PF13481.1 KKK15921.1 - 3.7e-07 29.7 3.6 0.47 9.8 0.0 4.5 2 2 1 4 4 4 3 AAA domain Mg_chelatase PF01078.16 KKK15921.1 - 3.9e-07 29.4 0.6 0.018 14.2 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI NACHT PF05729.7 KKK15921.1 - 6e-07 29.2 0.2 0.12 12.0 0.0 4.2 3 1 1 4 4 4 2 NACHT domain AAA_3 PF07726.6 KKK15921.1 - 7.4e-07 28.8 0.0 0.0025 17.4 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 KKK15921.1 - 1.9e-06 28.1 0.0 0.027 14.7 0.0 2.8 2 1 0 2 2 2 2 AAA domain KaiC PF06745.8 KKK15921.1 - 2.4e-05 23.5 0.1 0.49 9.4 0.0 3.3 2 1 1 3 3 3 2 KaiC Cytidylate_kin2 PF13189.1 KKK15921.1 - 2.6e-05 24.1 0.0 0.0034 17.3 0.0 2.4 2 0 0 2 2 2 1 Cytidylate kinase-like family Sigma54_activ_2 PF14532.1 KKK15921.1 - 2.8e-05 24.1 0.0 0.4 10.7 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain ABC_tran PF00005.22 KKK15921.1 - 2.9e-05 24.3 0.0 0.24 11.6 0.0 2.8 3 0 0 3 3 2 2 ABC transporter PhoH PF02562.11 KKK15921.1 - 4e-05 22.9 0.0 0.11 11.6 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein SKI PF01202.17 KKK15921.1 - 5.6e-05 23.0 0.0 0.19 11.5 0.0 2.7 2 0 0 2 2 2 2 Shikimate kinase Sigma54_activat PF00158.21 KKK15921.1 - 0.0001 21.8 0.0 0.29 10.5 0.0 3.0 3 0 0 3 3 3 2 Sigma-54 interaction domain Arch_ATPase PF01637.13 KKK15921.1 - 0.00013 21.7 0.0 2 8.0 0.0 3.6 2 2 1 3 3 3 2 Archaeal ATPase NB-ARC PF00931.17 KKK15921.1 - 0.00034 19.5 0.0 0.28 10.0 0.0 2.4 2 0 0 2 2 2 2 NB-ARC domain AFG1_ATPase PF03969.11 KKK15921.1 - 0.00042 19.2 0.0 0.12 11.1 0.0 2.8 2 1 0 2 2 2 1 AFG1-like ATPase Rad17 PF03215.10 KKK15921.1 - 0.00042 19.1 0.0 0.15 10.6 0.0 2.2 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein Parvo_NS1 PF01057.12 KKK15921.1 - 0.0011 17.9 0.0 1.3 7.8 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 ResIII PF04851.10 KKK15921.1 - 0.0012 18.6 0.0 2.6 7.8 0.0 2.6 2 1 0 2 2 2 2 Type III restriction enzyme, res subunit AAA_11 PF13086.1 KKK15921.1 - 0.0016 18.0 0.1 1.2 8.6 0.0 2.7 3 0 0 3 3 3 1 AAA domain Viral_helicase1 PF01443.13 KKK15921.1 - 0.0023 17.5 0.0 1.2 8.6 0.0 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase UPF0079 PF02367.12 KKK15921.1 - 0.0028 17.2 0.0 1.3 8.7 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 DUF815 PF05673.8 KKK15921.1 - 0.0033 16.3 0.0 0.066 12.1 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) ATP-synt_ab PF00006.20 KKK15921.1 - 0.0065 15.9 0.0 1.7 8.1 0.0 2.7 3 0 0 3 3 2 1 ATP synthase alpha/beta family, nucleotide-binding domain NTPase_1 PF03266.10 KKK15921.1 - 0.007 16.0 0.1 2.1 8.0 0.0 3.1 2 1 1 3 3 3 1 NTPase IPT PF01745.11 KKK15921.1 - 0.012 14.8 0.0 1.2 8.3 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase AAA_24 PF13479.1 KKK15921.1 - 0.013 15.0 0.1 1.5 8.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain CPT PF07931.7 KKK15921.1 - 0.033 13.8 0.0 0.81 9.2 0.0 2.4 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein DUF2075 PF09848.4 KKK15921.1 - 0.035 13.0 0.0 3.6 6.4 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.1 KKK15921.1 - 0.07 12.7 0.0 16 5.0 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_23 PF13476.1 KKK15921.1 - 0.077 13.3 0.2 3 8.1 0.0 2.7 3 0 0 3 3 2 0 AAA domain Ribosomal_L27 PF01016.14 KKK15946.1 - 5.3e-29 99.8 0.0 9.2e-29 99.0 0.0 1.4 1 0 0 1 1 1 1 Ribosomal L27 protein Rad9_Rad53_bind PF08605.5 KKK15947.1 - 5.1e-32 110.4 0.0 7.8e-32 109.8 0.0 1.3 1 0 0 1 1 1 1 Fungal Rad9-like Rad53-binding BRCT PF00533.21 KKK15947.1 - 4.7e-05 23.4 0.0 0.00078 19.5 0.0 2.9 2 1 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain tRNA_int_endo PF01974.12 KKK15948.1 - 8.7e-22 76.7 0.1 2.4e-21 75.3 0.1 1.8 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.9 KKK15948.1 - 3.5e-07 29.6 0.0 0.0042 16.6 0.0 2.4 2 0 0 2 2 2 2 tRNA intron endonuclease, N-terminal domain Nop10p PF04135.7 KKK15949.1 - 2.9e-23 81.3 0.3 3.5e-23 81.0 0.2 1.1 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family NOB1_Zn_bind PF08772.6 KKK15950.1 - 3.1e-33 113.4 4.3 5.6e-33 112.6 3.0 1.4 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like DZR PF12773.2 KKK15950.1 - 0.044 13.6 0.8 0.1 12.4 0.6 1.5 1 0 0 1 1 1 0 Double zinc ribbon zf-NADH-PPase PF09297.6 KKK15950.1 - 0.5 9.9 4.5 0.14 11.6 0.3 2.1 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain AF1Q PF15017.1 KKK15950.1 - 0.58 10.1 13.8 3.3 7.6 9.3 2.3 1 1 0 1 1 1 0 Drug resistance and apoptosis regulator RR_TM4-6 PF06459.7 KKK15950.1 - 5.2 6.8 9.8 7.9 6.2 6.8 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PrgI PF12666.2 KKK15951.1 - 5.3 7.2 8.5 13 6.0 1.5 2.6 2 0 0 2 2 2 0 PrgI family protein Peptidase_M18 PF02127.10 KKK15952.1 - 3.4e-132 440.9 0.0 3.9e-132 440.8 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) UQ_con PF00179.21 KKK15953.1 - 4.4e-51 171.9 0.0 5e-51 171.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 KKK15953.1 - 0.11 12.3 0.2 0.19 11.6 0.1 1.8 1 1 0 1 1 1 0 RWD domain Scramblase PF03803.10 KKK15954.1 - 2.6e-54 183.6 1.1 3.5e-29 101.4 0.1 3.0 2 1 0 2 2 2 2 Scramblase Ribosomal_S18 PF01084.15 KKK15954.1 - 0.098 12.5 0.1 0.22 11.4 0.1 1.5 1 0 0 1 1 1 0 Ribosomal protein S18 SGS PF05002.10 KKK15955.1 - 1.8e-27 94.9 1.7 1.8e-27 94.9 1.1 1.8 2 0 0 2 2 2 1 SGS domain CS PF04969.11 KKK15955.1 - 2.9e-12 46.9 0.0 4.7e-12 46.2 0.0 1.4 1 0 0 1 1 1 1 CS domain TPR_11 PF13414.1 KKK15955.1 - 2e-06 27.3 0.3 4.3e-05 23.0 0.0 2.2 1 1 1 2 2 2 1 TPR repeat TPR_2 PF07719.12 KKK15955.1 - 0.0013 18.4 0.3 1.5 8.9 0.1 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 KKK15955.1 - 0.0015 18.0 0.0 1.6 8.4 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 KKK15955.1 - 0.0047 17.5 3.6 0.32 11.7 0.1 2.3 1 1 1 2 2 2 1 Tetratricopeptide repeat Dicty_REP PF05086.7 KKK15955.1 - 0.21 9.2 4.8 0.27 8.9 3.3 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Prenyltrans PF00432.16 KKK15956.1 - 2.6e-33 113.2 7.4 3.2e-11 42.6 0.2 5.1 5 0 0 5 5 5 3 Prenyltransferase and squalene oxidase repeat Prenyltrans_1 PF13243.1 KKK15956.1 - 8.6e-28 96.5 0.1 5.6e-17 61.7 0.2 5.4 3 2 1 5 5 5 4 Prenyltransferase-like Prenyltrans_2 PF13249.1 KKK15956.1 - 2.2e-27 95.7 0.7 3.7e-16 59.5 0.2 5.0 4 1 1 5 5 5 3 Prenyltransferase-like Pec_lyase PF09492.5 KKK15956.1 - 1.5e-08 34.2 5.1 0.51 9.4 0.0 5.9 3 2 2 6 6 6 3 Pectic acid lyase TSGP1 PF07771.6 KKK15956.1 - 0.03 14.1 0.0 0.063 13.1 0.0 1.4 1 0 0 1 1 1 0 Tick salivary peptide group 1 DUF3469 PF11952.3 KKK15956.1 - 0.032 13.8 0.1 0.077 12.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3469) Mago-bind PF09282.5 KKK15956.1 - 0.13 11.8 0.0 0.26 10.8 0.0 1.5 1 0 0 1 1 1 0 Mago binding TP6A_N PF04406.9 KKK15957.1 - 2e-17 62.6 0.0 3.7e-17 61.7 0.0 1.4 1 0 0 1 1 1 1 Type IIB DNA topoisomerase Pkinase PF00069.20 KKK15958.1 - 5.9e-76 255.0 0.0 7.2e-76 254.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK15958.1 - 2.3e-37 128.4 0.0 3.4e-37 127.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KKK15958.1 - 0.00037 19.5 0.5 0.00087 18.3 0.0 1.9 2 1 0 2 2 2 1 Kinase-like CAP_N PF01213.14 KKK15958.1 - 0.0038 16.5 1.3 0.0063 15.8 0.9 1.3 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal Kdo PF06293.9 KKK15958.1 - 0.0046 16.0 1.8 0.0057 15.7 0.1 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KKK15958.1 - 0.13 12.0 1.4 0.2 11.3 0.1 2.1 2 1 0 2 2 2 0 Phosphotransferase enzyme family Mito_fiss_reg PF05308.6 KKK15958.1 - 5.9 6.1 9.3 0.2 10.9 2.1 1.7 2 0 0 2 2 2 0 Mitochondrial fission regulator SIR2 PF02146.12 KKK15959.1 - 7.8e-31 107.1 0.0 1.1e-30 106.6 0.0 1.2 1 0 0 1 1 1 1 Sir2 family DUF3716 PF12511.3 KKK15960.1 - 3.8e-16 58.4 6.1 5.8e-16 57.8 4.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) Prothymosin PF03247.9 KKK15960.1 - 0.00073 19.6 40.6 0.0011 19.0 13.8 2.2 2 0 0 2 2 2 1 Prothymosin/parathymosin family CobT PF06213.7 KKK15960.1 - 0.001 18.2 0.8 0.001 18.2 0.5 2.2 2 0 0 2 2 2 1 Cobalamin biosynthesis protein CobT HCMV_UL139 PF12507.3 KKK15960.1 - 0.0014 18.7 0.3 0.58 10.3 0.0 2.7 1 1 1 2 2 2 1 Human Cytomegalovirus UL139 protein DUF2052 PF09747.4 KKK15960.1 - 0.0036 17.2 5.1 0.0036 17.2 3.5 2.1 2 0 0 2 2 2 1 Coiled-coil domain containing protein (DUF2052) CENP-B_dimeris PF09026.5 KKK15960.1 - 0.0037 17.4 7.3 0.0037 17.4 5.1 2.3 2 0 0 2 2 2 1 Centromere protein B dimerisation domain Trypan_glycop_C PF10659.4 KKK15960.1 - 0.004 17.4 1.9 0.004 17.4 1.3 2.2 2 0 0 2 2 2 1 Trypanosome variant surface glycoprotein C-terminal domain Nucleoplasmin PF03066.10 KKK15960.1 - 0.049 13.1 31.3 0.23 10.9 2.4 2.2 2 0 0 2 2 2 0 Nucleoplasmin RNase_H2_suC PF08615.6 KKK15960.1 - 0.058 13.2 2.8 1.1 9.0 0.0 2.2 2 0 0 2 2 2 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Gcd10p PF04189.8 KKK15960.1 - 0.091 11.8 3.3 0.71 8.9 0.5 2.1 2 0 0 2 2 2 0 Gcd10p family Tim54 PF11711.3 KKK15960.1 - 0.091 11.3 7.8 0.022 13.3 0.6 2.0 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 Nop14 PF04147.7 KKK15960.1 - 0.1 10.5 17.8 0.018 13.0 4.9 2.0 2 0 0 2 2 2 0 Nop14-like family FYDLN_acid PF09538.5 KKK15960.1 - 0.16 12.5 13.6 0.4 11.2 4.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) PBP1_TM PF14812.1 KKK15960.1 - 0.23 11.7 14.8 0.12 12.7 3.2 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal eIF-3c_N PF05470.7 KKK15960.1 - 0.35 8.8 8.8 0.5 8.3 6.1 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Spore_coat_CotO PF14153.1 KKK15960.1 - 0.37 10.2 16.6 0.047 13.1 3.2 2.1 2 0 0 2 2 2 0 Spore coat protein CotO RNA_pol_Rpc4 PF05132.9 KKK15960.1 - 0.42 10.5 9.7 1.1 9.2 1.9 2.2 2 0 0 2 2 2 0 RNA polymerase III RPC4 Hex_IIIa PF02455.11 KKK15960.1 - 0.57 8.8 2.5 0.76 8.3 1.7 1.1 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) BSP_II PF05432.6 KKK15960.1 - 0.69 9.1 33.2 0.057 12.7 10.6 2.2 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) PRP21_like_P PF12230.3 KKK15960.1 - 0.71 9.3 16.5 0.096 12.1 3.9 2.1 2 0 0 2 2 2 0 Pre-mRNA splicing factor PRP21 like protein Vfa1 PF08432.5 KKK15960.1 - 0.88 9.5 13.8 0.34 10.9 2.1 2.1 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 DUF4366 PF14283.1 KKK15960.1 - 1.5 8.1 14.4 0.04 13.3 1.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) CDV3 PF15359.1 KKK15960.1 - 2 8.5 19.2 0.09 12.8 1.9 2.9 3 0 0 3 3 3 0 Carnitine deficiency-associated protein 3 FAM176 PF14851.1 KKK15960.1 - 2.1 7.9 17.0 0.084 12.5 3.5 2.2 2 0 0 2 2 2 0 FAM176 family TraV PF09676.5 KKK15960.1 - 2.2 9.0 6.5 0.55 10.9 0.8 2.2 2 0 0 2 2 2 0 Type IV conjugative transfer system lipoprotein (TraV) OAD_gamma PF04277.8 KKK15960.1 - 2.9 8.3 8.8 1.7 9.0 1.0 2.3 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain PI3K_1B_p101 PF10486.4 KKK15960.1 - 3.5 5.0 10.2 4.5 4.7 6.7 1.4 1 1 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Daxx PF03344.10 KKK15960.1 - 4.1 5.7 29.1 0.27 9.6 10.1 2.1 2 0 0 2 2 2 0 Daxx Family TLP-20 PF06088.6 KKK15960.1 - 7.3 6.2 9.6 0.78 9.3 1.4 2.1 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) YqfQ PF14181.1 KKK15960.1 - 8.2 6.4 16.9 5.7 6.9 4.9 2.5 2 0 0 2 2 2 0 YqfQ-like protein DUF1510 PF07423.6 KKK15960.1 - 9.7 5.4 22.4 5.5 6.3 7.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) PQ-loop PF04193.9 KKK15961.1 - 7.9e-40 134.2 17.6 7.9e-21 73.3 0.9 3.1 3 0 0 3 3 3 2 PQ loop repeat TspO_MBR PF03073.10 KKK15961.1 - 0.045 13.2 1.9 1.9 7.9 0.0 2.9 2 1 1 3 3 3 0 TspO/MBR family Dicty_CAR PF05462.6 KKK15962.1 - 2.4e-14 52.9 17.2 5.1e-13 48.5 8.3 2.1 2 0 0 2 2 2 2 Slime mold cyclic AMP receptor 7tm_2 PF00002.19 KKK15962.1 - 6.7e-12 45.0 8.7 1.1e-11 44.3 6.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Git3 PF11710.3 KKK15962.1 - 5.4e-07 29.3 13.5 5.4e-07 29.3 9.4 1.5 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 7TM_GPCR_Srsx PF10320.4 KKK15962.1 - 0.0009 18.4 3.5 0.0009 18.4 2.4 1.8 3 0 0 3 3 3 1 Serpentine type 7TM GPCR chemoreceptor Srsx SRP54 PF00448.17 KKK15963.1 - 8.5e-75 250.5 3.5 1.5e-74 249.7 2.4 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.14 KKK15963.1 - 4.3e-24 84.7 0.5 4.3e-24 84.7 0.3 4.3 5 1 0 5 5 4 1 Signal peptide binding domain SRP54_N PF02881.14 KKK15963.1 - 6.3e-17 61.4 0.4 1.4e-16 60.3 0.3 1.6 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain cobW PF02492.14 KKK15963.1 - 5.1e-09 35.8 0.2 1.1e-08 34.7 0.2 1.6 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 KKK15963.1 - 1.4e-06 28.2 0.2 4.5e-06 26.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KKK15963.1 - 3e-05 24.8 0.0 6.6e-05 23.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 KKK15963.1 - 5.4e-05 22.9 0.1 0.00014 21.5 0.0 1.8 2 0 0 2 2 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_31 PF13614.1 KKK15963.1 - 0.00011 22.2 0.0 0.17 11.8 0.0 2.7 3 0 0 3 3 3 2 AAA domain CbiA PF01656.18 KKK15963.1 - 0.00021 20.7 0.3 0.00067 19.1 0.2 1.8 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain APS_kinase PF01583.15 KKK15963.1 - 0.00094 18.8 0.0 0.0019 17.8 0.0 1.5 1 0 0 1 1 1 1 Adenylylsulphate kinase Zeta_toxin PF06414.7 KKK15963.1 - 0.001 18.1 0.1 0.0021 17.2 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin ArgK PF03308.11 KKK15963.1 - 0.0016 17.2 0.0 0.0016 17.2 0.0 2.4 3 1 1 4 4 4 1 ArgK protein SRPRB PF09439.5 KKK15963.1 - 0.0017 17.5 1.2 1.2 8.3 0.7 3.1 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.1 KKK15963.1 - 0.0019 18.2 0.1 0.0072 16.3 0.0 2.1 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KKK15963.1 - 0.0055 16.8 0.0 0.018 15.1 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KKK15963.1 - 0.0081 16.4 0.0 0.018 15.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain 6PF2K PF01591.13 KKK15963.1 - 0.0091 15.0 0.0 0.015 14.3 0.0 1.3 1 0 0 1 1 1 1 6-phosphofructo-2-kinase ATP_bind_1 PF03029.12 KKK15963.1 - 0.012 15.1 0.4 0.034 13.6 0.0 1.9 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_28 PF13521.1 KKK15963.1 - 0.017 15.1 0.1 0.035 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.12 KKK15963.1 - 0.017 14.5 0.1 0.055 12.8 0.0 1.9 1 0 0 1 1 1 0 Thymidylate kinase AAA_10 PF12846.2 KKK15963.1 - 0.048 13.0 0.0 0.081 12.3 0.0 1.5 1 1 0 1 1 1 0 AAA-like domain PduV-EutP PF10662.4 KKK15963.1 - 0.1 12.1 1.0 0.43 10.0 0.1 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Arf PF00025.16 KKK15963.1 - 0.11 11.6 0.0 0.29 10.3 0.0 1.6 1 0 0 1 1 1 0 ADP-ribosylation factor family Rrp15p PF07890.7 KKK15964.1 - 9.4e-36 122.7 8.0 9.4e-36 122.7 5.5 2.3 2 1 0 2 2 2 1 Rrp15p Atrophin-1 PF03154.10 KKK15964.1 - 0.38 8.8 14.5 0.51 8.4 10.0 1.3 1 0 0 1 1 1 0 Atrophin-1 family CDC45 PF02724.9 KKK15964.1 - 2.4 6.0 14.9 3.8 5.4 10.3 1.4 1 0 0 1 1 1 0 CDC45-like protein TEX19 PF15553.1 KKK15964.1 - 4.3 7.1 5.7 10 5.9 4.0 1.7 1 0 0 1 1 1 0 Testis-expressed protein 19 Fer2 PF00111.22 KKK15965.1 - 6.6e-13 48.2 0.8 9.4e-13 47.7 0.6 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Mito_carr PF00153.22 KKK15966.1 - 9.8e-10 38.0 2.7 0.49 10.1 0.0 5.1 4 1 0 4 4 4 3 Mitochondrial carrier protein Sporozoite_P67 PF05642.6 KKK15966.1 - 0.32 8.8 3.5 0.58 7.9 2.4 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen PBP1_TM PF14812.1 KKK15966.1 - 0.61 10.4 5.0 1.1 9.5 3.5 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Hap4_Hap_bind PF10297.4 KKK15967.1 - 1.7e-08 33.9 6.0 1.7e-08 33.9 4.2 2.1 2 0 0 2 2 2 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 bZIP_1 PF00170.16 KKK15967.1 - 1.1e-07 31.7 10.6 2.9e-06 27.1 7.4 2.7 1 1 1 2 2 2 1 bZIP transcription factor DUF2408 PF10303.4 KKK15967.1 - 0.0019 18.2 0.2 0.0034 17.5 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2408) FlaC_arch PF05377.6 KKK15967.1 - 0.072 12.9 1.2 0.15 11.9 0.8 1.5 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) dsrm PF00035.20 KKK15967.1 - 0.12 13.0 0.0 0.26 11.8 0.0 1.6 1 0 0 1 1 1 0 Double-stranded RNA binding motif Phage_int_SAM_5 PF13102.1 KKK15967.1 - 0.15 12.0 0.3 0.26 11.2 0.2 1.3 1 0 0 1 1 1 0 Phage integrase SAM-like domain Mnd1 PF03962.10 KKK15967.1 - 0.16 11.5 3.3 0.28 10.8 2.3 1.3 1 0 0 1 1 1 0 Mnd1 family bZIP_2 PF07716.10 KKK15967.1 - 0.61 9.9 17.6 0.078 12.8 6.6 2.9 2 1 1 3 3 3 0 Basic region leucine zipper Glyco_hydro_71 PF03659.9 KKK15968.1 - 7.4e-157 521.7 0.4 9.9e-157 521.3 0.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 Pkinase PF00069.20 KKK15998.1 - 3.6e-17 62.3 0.0 9.1e-17 61.0 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK15998.1 - 0.00048 19.2 0.0 0.00073 18.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase GCS PF03074.11 KKK15999.1 - 3.2e-154 513.4 0.0 9.6e-154 511.8 0.0 1.7 1 1 0 1 1 1 1 Glutamate-cysteine ligase NDUF_B7 PF05676.8 KKK16000.1 - 7.3e-33 111.8 5.4 8.6e-33 111.5 3.7 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.5 KKK16000.1 - 0.0063 16.2 2.7 0.0086 15.8 1.9 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Ank_2 PF12796.2 KKK16001.1 - 5.4e-13 49.0 0.1 2.1e-08 34.3 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KKK16001.1 - 2.7e-12 45.8 1.2 8.6e-09 34.7 0.1 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 KKK16001.1 - 5e-12 45.9 0.2 4.1e-06 27.1 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 KKK16001.1 - 5.4e-12 45.5 0.3 6.1e-07 29.4 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KKK16001.1 - 3.8e-10 38.9 0.5 0.00013 21.8 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat KilA-N PF04383.8 KKK16001.1 - 0.00015 21.3 0.0 0.00049 19.6 0.0 1.9 1 0 0 1 1 1 1 KilA-N domain HALZ PF02183.13 KKK16001.1 - 0.12 12.1 3.5 0.94 9.2 0.0 2.6 2 0 0 2 2 2 0 Homeobox associated leucine zipper DUF1212 PF06738.7 KKK16003.1 - 1.2e-55 187.9 19.7 2e-53 180.7 0.1 2.8 4 0 0 4 4 4 2 Protein of unknown function (DUF1212) DUF3815 PF12821.2 KKK16003.1 - 9.1e-30 103.2 13.5 9.1e-30 103.2 9.4 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3815) CaMKII_AD PF08332.5 KKK16004.1 - 0.0078 16.1 0.0 0.014 15.2 0.0 1.4 1 1 0 1 1 1 1 Calcium/calmodulin dependent protein kinase II Association DUF4440 PF14534.1 KKK16004.1 - 0.066 13.4 0.0 0.082 13.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) 2OG-FeII_Oxy_3 PF13640.1 KKK16005.1 - 8.4e-07 29.4 0.1 1.6e-06 28.5 0.1 1.5 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 KKK16005.1 - 0.00093 18.7 0.1 0.0018 17.8 0.1 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily adh_short_C2 PF13561.1 KKK16006.1 - 9.7e-26 91.0 0.0 1.7e-15 57.4 0.0 2.0 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KKK16006.1 - 9.5e-24 84.1 1.1 5.1e-21 75.2 0.2 2.1 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 KKK16006.1 - 7.1e-13 48.6 0.1 1.1e-12 47.9 0.1 1.2 1 0 0 1 1 1 1 KR domain Alk_phosphatase PF00245.15 KKK16006.1 - 0.043 12.5 0.0 0.058 12.0 0.0 1.2 1 0 0 1 1 1 0 Alkaline phosphatase PLA2_B PF01735.13 KKK16007.1 - 1e-178 594.5 12.9 1e-161 538.4 0.4 2.1 1 1 1 2 2 2 2 Lysophospholipase catalytic domain Xpo1 PF08389.7 KKK16018.1 - 2.3e-09 37.2 7.4 1.5e-08 34.7 1.0 4.5 4 2 1 5 5 5 1 Exportin 1-like protein HEAT_2 PF13646.1 KKK16018.1 - 0.0002 21.5 0.4 0.0074 16.5 0.0 3.6 4 0 0 4 4 4 1 HEAT repeats Arabinose_trans PF04602.7 KKK16018.1 - 0.064 11.4 0.0 0.099 10.8 0.0 1.2 1 0 0 1 1 1 0 Mycobacterial cell wall arabinan synthesis protein GRIM-19 PF06212.7 KKK16019.1 - 4.9e-21 74.7 0.1 1e-20 73.7 0.1 1.5 1 1 0 1 1 1 1 GRIM-19 protein tRNA_m1G_MT PF01746.16 KKK16020.1 - 2.6e-31 108.6 0.0 9.1e-31 106.8 0.0 1.9 1 1 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase VID27 PF08553.5 KKK16021.1 - 0 1170.7 0.6 0 1170.6 0.4 1.0 1 0 0 1 1 1 1 VID27 cytoplasmic protein Nop14 PF04147.7 KKK16021.1 - 2.6 5.8 16.9 4.7 5.0 11.7 1.3 1 0 0 1 1 1 0 Nop14-like family HATPase_c PF02518.21 KKK16029.1 - 1.4e-11 44.0 0.1 2.7e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DNA_mis_repair PF01119.14 KKK16029.1 - 1.5e-11 43.7 0.0 3.4e-11 42.6 0.0 1.6 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 KKK16029.1 - 3.6e-09 36.4 0.0 9.1e-09 35.0 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase zf-DHHC PF01529.15 KKK16030.1 - 1.2e-33 115.9 2.0 2.5e-33 114.9 1.4 1.5 1 0 0 1 1 1 1 DHHC palmitoyltransferase Transglut_core3 PF13471.1 KKK16030.1 - 0.094 12.5 3.5 0.21 11.4 2.4 1.5 1 0 0 1 1 1 0 Transglutaminase-like superfamily Methyltransf_11 PF08241.7 KKK16031.1 - 4.4e-15 55.9 0.0 7.9e-15 55.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KKK16031.1 - 7.2e-14 51.8 0.0 1.1e-13 51.2 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KKK16031.1 - 7.2e-13 48.8 0.0 1.1e-12 48.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KKK16031.1 - 1.7e-12 47.9 0.0 2.5e-12 47.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KKK16031.1 - 2.6e-11 43.3 0.0 3.4e-11 42.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KKK16031.1 - 1.9e-08 34.5 0.0 4.4e-08 33.3 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 KKK16031.1 - 2.8e-08 33.3 0.0 4.1e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 KKK16031.1 - 8.7e-08 32.2 0.0 1.7e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 KKK16031.1 - 4.8e-06 25.7 0.0 7.3e-06 25.1 0.0 1.4 1 1 0 1 1 1 1 Ribosomal RNA adenine dimethylase NodS PF05401.6 KKK16031.1 - 6.8e-06 25.6 0.0 1.3e-05 24.7 0.0 1.4 2 0 0 2 2 2 1 Nodulation protein S (NodS) Methyltransf_9 PF08003.6 KKK16031.1 - 2.1e-05 23.3 0.0 3.4e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) PCMT PF01135.14 KKK16031.1 - 5.8e-05 22.7 0.0 0.00014 21.4 0.0 1.8 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.13 KKK16031.1 - 5.9e-05 22.2 0.0 8.7e-05 21.7 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family DREV PF05219.7 KKK16031.1 - 0.00026 19.9 0.0 0.00036 19.5 0.0 1.3 1 0 0 1 1 1 1 DREV methyltransferase PrmA PF06325.8 KKK16031.1 - 0.0013 17.9 0.0 0.0018 17.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.15 KKK16031.1 - 0.0041 16.2 0.0 0.0053 15.8 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase FtsJ PF01728.14 KKK16031.1 - 0.0074 16.2 0.0 0.017 15.1 0.0 1.6 1 1 0 1 1 1 1 FtsJ-like methyltransferase TPMT PF05724.6 KKK16031.1 - 0.0086 15.5 0.0 0.13 11.6 0.0 2.2 2 0 0 2 2 2 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_32 PF13679.1 KKK16031.1 - 0.085 12.5 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain tRNA_U5-meth_tr PF05958.6 KKK16031.1 - 0.18 10.4 0.0 0.25 9.9 0.0 1.1 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase DUF202 PF02656.10 KKK16032.1 - 2.3e-18 66.1 0.4 4.2e-18 65.3 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF202) DUF3112 PF11309.3 KKK16033.1 - 1.3e-40 138.8 15.9 1.2e-37 129.1 4.5 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3112) DUF4407 PF14362.1 KKK16033.1 - 0.0051 15.8 1.7 0.0054 15.7 0.5 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4407) EthD PF07110.6 KKK16034.1 - 0.008 17.0 0.1 0.042 14.7 0.1 1.9 1 1 0 1 1 1 1 EthD domain PBP PF01161.15 KKK16035.1 - 7.2e-18 64.8 0.1 8.9e-18 64.5 0.1 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein 2-Hacid_dh_C PF02826.14 KKK16036.1 - 9.8e-33 112.7 0.2 3.1e-26 91.6 0.0 2.2 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain MBOAT_2 PF13813.1 KKK16037.1 - 1.2e-19 70.2 5.4 2.6e-19 69.0 3.8 1.7 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family WD40 PF00400.27 KKK16039.1 - 6.7e-09 35.3 0.7 6.8e-07 28.9 0.0 4.2 4 0 0 4 4 4 1 WD domain, G-beta repeat DUF1090 PF06476.7 KKK16040.1 - 0.042 13.5 0.0 0.07 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1090) FSH1 PF03959.8 KKK16041.1 - 1.7e-27 96.2 0.0 2.2e-27 95.8 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 KKK16041.1 - 3e-08 33.8 1.1 1.3e-06 28.4 0.8 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KKK16041.1 - 6.3e-06 26.0 0.0 1.1e-05 25.1 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 KKK16041.1 - 0.005 16.3 0.1 0.29 10.5 0.0 2.4 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.8 KKK16041.1 - 0.067 12.7 0.2 0.76 9.3 0.0 2.1 2 0 0 2 2 2 0 alpha/beta hydrolase fold Prok_Ub PF14454.1 KKK16041.1 - 0.12 12.0 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic Ubiquitin ketoacyl-synt PF00109.21 KKK16042.1 - 1.9e-53 181.5 0.5 1.4e-52 178.7 0.1 2.6 3 1 0 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 KKK16042.1 - 5.9e-36 122.9 0.6 1.2e-35 121.9 0.4 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.16 KKK16042.1 - 1.6e-28 100.0 0.3 4.4e-27 95.2 0.0 2.6 3 0 0 3 3 3 1 Acyl transferase domain PS-DH PF14765.1 KKK16042.1 - 1.9e-22 79.7 0.0 3.3e-22 78.9 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Methyltransf_23 PF13489.1 KKK16042.1 - 7.2e-16 58.3 0.1 1.1e-14 54.4 0.0 2.7 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_12 PF08242.7 KKK16042.1 - 4.1e-14 52.8 0.0 9.7e-14 51.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 KKK16042.1 - 2.9e-12 46.6 1.2 7.4e-12 45.3 0.9 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_11 PF08241.7 KKK16042.1 - 5.2e-08 33.2 0.1 3.2e-07 30.7 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KKK16042.1 - 2.2e-07 30.5 0.0 6.3e-07 29.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KKK16042.1 - 1.5e-05 25.5 0.0 5.3e-05 23.7 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.18 KKK16042.1 - 2.5e-05 23.3 0.3 6.1e-05 22.1 0.0 1.7 2 0 0 2 2 2 1 Thiolase, N-terminal domain Methyltransf_25 PF13649.1 KKK16042.1 - 3.6e-05 24.0 0.0 9.4e-05 22.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KKK16042.1 - 0.0017 18.3 0.0 0.0079 16.2 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_28 PF02636.12 KKK16042.1 - 0.0054 16.1 0.0 0.0093 15.3 0.0 1.3 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Ubie_methyltran PF01209.13 KKK16042.1 - 0.0061 15.7 0.0 0.018 14.1 0.0 1.7 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family ACP_syn_III PF08545.5 KKK16042.1 - 0.57 9.8 4.2 0.41 10.3 0.2 2.5 2 1 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ER_lumen_recept PF00810.13 KKK16059.1 - 1.7e-58 197.2 8.8 2.6e-58 196.6 6.1 1.3 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.9 KKK16059.1 - 0.00055 19.4 10.3 0.42 10.2 0.2 4.0 3 1 1 4 4 4 3 PQ loop repeat XRCC4 PF06632.7 KKK16062.1 - 3.3e-08 32.7 9.1 8.6e-08 31.4 6.3 1.8 1 1 0 1 1 1 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 DUF3585 PF12130.3 KKK16062.1 - 0.0098 15.7 2.2 0.021 14.7 1.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3585) CCDC-167 PF15188.1 KKK16062.1 - 0.1 12.5 0.3 0.1 12.5 0.2 2.7 2 1 0 2 2 2 0 Coiled-coil domain-containing protein 167 Ribonuclease_3 PF00636.21 KKK16063.1 - 7.2e-16 58.6 0.0 6.1e-15 55.6 0.0 2.3 2 0 0 2 2 2 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 KKK16063.1 - 4.3e-12 46.1 0.0 7.4e-12 45.3 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease-III-like dsrm PF00035.20 KKK16063.1 - 4.1e-05 24.0 0.1 0.0001 22.8 0.1 1.7 1 0 0 1 1 1 1 Double-stranded RNA binding motif Cys_Met_Meta_PP PF01053.15 KKK16065.1 - 6e-149 495.5 0.0 6.8e-149 495.3 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 KKK16065.1 - 2.8e-13 49.6 1.8 2.8e-13 49.6 1.2 1.5 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.16 KKK16065.1 - 1e-08 34.5 0.2 1.7e-08 33.8 0.1 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 KKK16065.1 - 1.4e-07 30.6 0.7 4.4e-07 28.9 0.5 1.7 1 1 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 KKK16065.1 - 8.9e-07 28.3 0.0 1.6e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Met_gamma_lyase PF06838.6 KKK16065.1 - 0.00019 19.8 0.0 0.00024 19.5 0.0 1.1 1 0 0 1 1 1 1 Methionine gamma-lyase GDC-P PF02347.11 KKK16065.1 - 0.024 13.3 0.0 0.035 12.8 0.0 1.1 1 0 0 1 1 1 0 Glycine cleavage system P-protein SLA_LP_auto_ag PF05889.8 KKK16065.1 - 0.086 11.2 0.0 0.12 10.7 0.0 1.2 1 0 0 1 1 1 0 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) RRM_1 PF00076.17 KKK16066.1 - 1e-05 25.0 0.0 1.9e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KKK16066.1 - 3.4e-05 23.5 0.0 6e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CTD_bind PF04818.8 KKK16066.1 - 0.00031 20.9 0.0 0.0013 18.9 0.0 1.9 1 1 0 1 1 1 1 RNA polymerase II-binding domain. RRM_6 PF14259.1 KKK16066.1 - 0.001 19.0 0.0 0.002 18.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) PAP1 PF08601.5 KKK16066.1 - 7.4 6.1 10.8 12 5.4 7.5 1.3 1 0 0 1 1 1 0 Transcription factor PAP1 AA_permease PF00324.16 KKK16067.1 - 5.9e-132 440.3 51.6 7.1e-132 440.1 35.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KKK16067.1 - 9.3e-35 119.9 58.1 1.2e-34 119.6 40.3 1.1 1 0 0 1 1 1 1 Amino acid permease MARVEL PF01284.18 KKK16068.1 - 9.1e-23 80.6 15.1 1.1e-22 80.4 10.4 1.1 1 0 0 1 1 1 1 Membrane-associating domain DUF1385 PF07136.6 KKK16068.1 - 0.08 12.0 0.5 0.11 11.5 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1385) DUF2304 PF10066.4 KKK16068.1 - 2.5 7.9 8.4 0.68 9.8 3.1 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2304) Peptidase_M16 PF00675.15 KKK16069.1 - 7.3e-22 77.7 0.0 1.6e-21 76.6 0.0 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 KKK16069.1 - 5.1e-17 62.1 0.0 9.9e-17 61.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase M16 inactive domain RNA_pol_Rpc82 PF05645.8 KKK16070.1 - 8.1e-26 91.0 0.0 2.1e-23 83.2 0.0 2.3 2 0 0 2 2 2 2 RNA polymerase III subunit RPC82 HTH_9 PF08221.6 KKK16070.1 - 1.2e-15 57.0 1.3 5.2e-09 35.8 0.0 3.6 4 0 0 4 4 4 3 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.12 KKK16070.1 - 3.7e-07 29.5 0.3 0.00034 20.0 0.1 2.6 2 0 0 2 2 2 2 TFIIE alpha subunit PBP1_TM PF14812.1 KKK16070.1 - 0.026 14.8 2.6 0.11 12.7 1.8 2.1 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Citrate_synt PF00285.16 KKK16071.1 - 1.5e-101 339.6 0.0 1.8e-101 339.4 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase Mito_carr PF00153.22 KKK16072.1 - 1.3e-27 95.3 6.1 2.4e-12 46.4 0.0 3.3 3 1 0 3 3 3 3 Mitochondrial carrier protein DUF2012 PF09430.5 KKK16073.1 - 1.6e-21 76.4 0.0 3.4e-21 75.3 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF2012) AMP-binding PF00501.23 KKK16074.1 - 7e-79 265.1 0.0 1e-78 264.6 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme WW PF00397.21 KKK16075.1 - 6.7e-10 38.6 1.0 1.7e-09 37.3 0.7 1.7 1 0 0 1 1 1 1 WW domain WD40 PF00400.27 KKK16076.1 - 7e-15 54.2 8.3 4.4e-06 26.3 0.0 6.5 7 0 0 7 7 7 4 WD domain, G-beta repeat Raptor_N PF14538.1 KKK16076.1 - 0.094 12.5 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Raptor N-terminal CASPase like domain Mito_carr PF00153.22 KKK16077.1 - 5.2e-49 163.9 1.4 5.5e-18 64.4 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein UcrQ PF02939.11 KKK16077.1 - 0.0025 17.5 0.2 0.0099 15.6 0.1 2.0 2 0 0 2 2 2 1 UcrQ family AphA_like PF14557.1 KKK16077.1 - 0.018 14.6 0.0 0.045 13.3 0.0 1.6 2 0 0 2 2 2 0 Putative AphA-like transcriptional regulator Ras PF00071.17 KKK16078.1 - 3e-23 81.9 0.3 3.6e-23 81.7 0.2 1.1 1 0 0 1 1 1 1 Ras family Peptidase_M1 PF01433.15 KKK16079.1 - 1.2e-131 439.4 0.6 2.6e-131 438.3 0.1 1.7 2 0 0 2 2 2 1 Peptidase family M1 ERAP1_C PF11838.3 KKK16079.1 - 4e-73 246.4 6.7 6.2e-73 245.8 4.7 1.3 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 KKK16079.1 - 4.7e-22 78.3 1.8 9.4e-22 77.4 1.2 1.5 1 0 0 1 1 1 1 Peptidase MA superfamily Ssl1 PF04056.9 KKK16080.1 - 7.6e-77 257.2 0.0 1.1e-76 256.7 0.0 1.2 1 0 0 1 1 1 1 Ssl1-like VWA_2 PF13519.1 KKK16080.1 - 9.3e-12 45.3 0.0 1.5e-11 44.7 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 KKK16080.1 - 0.00062 19.5 0.0 0.0011 18.7 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain PsiE PF06146.7 KKK16080.1 - 0.0046 17.1 0.0 0.0087 16.2 0.0 1.5 1 0 0 1 1 1 1 Phosphate-starvation-inducible E Tfb4 PF03850.9 KKK16080.1 - 0.08 12.1 2.1 0.12 11.6 1.5 1.2 1 0 0 1 1 1 0 Transcription factor Tfb4 PUF PF00806.14 KKK16081.1 - 4.1e-36 120.4 3.6 2.2e-06 26.8 0.0 9.2 9 0 0 9 9 9 8 Pumilio-family RNA binding repeat Abhydrolase_5 PF12695.2 KKK16082.1 - 1.3e-09 37.9 0.5 2.2e-09 37.2 0.3 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KKK16082.1 - 4.8e-09 36.4 3.3 3.4e-08 33.6 2.3 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KKK16082.1 - 9.7e-07 28.2 0.0 1.9e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.15 KKK16082.1 - 3.4e-05 23.4 0.8 0.00014 21.3 0.5 1.9 1 1 0 1 1 1 1 Putative esterase Abhydrolase_2 PF02230.11 KKK16082.1 - 3.8e-05 23.2 0.7 0.0048 16.3 0.0 3.0 2 1 1 3 3 3 1 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.15 KKK16082.1 - 0.002 17.7 0.1 0.0079 15.7 0.0 1.9 1 1 1 2 2 2 1 alpha/beta hydrolase fold Chlorophyllase PF07224.6 KKK16082.1 - 0.0041 15.9 0.1 0.0068 15.2 0.1 1.2 1 0 0 1 1 1 1 Chlorophyllase Esterase_phd PF10503.4 KKK16082.1 - 0.022 14.0 0.8 0.044 13.0 0.5 1.5 1 1 0 1 1 1 0 Esterase PHB depolymerase TPT PF03151.11 KKK16083.1 - 7.1e-37 126.4 4.9 7.1e-37 126.4 3.4 2.0 2 0 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 KKK16083.1 - 3.3e-08 32.8 13.8 2.7e-07 29.8 9.6 2.0 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 KKK16083.1 - 0.0005 20.1 34.7 0.013 15.5 6.6 3.1 3 1 0 3 3 3 2 EamA-like transporter family Molybdopterin PF00384.17 KKK16084.1 - 7e-69 232.6 0.0 6e-35 120.8 0.0 2.2 1 1 1 2 2 2 2 Molybdopterin oxidoreductase NADH-G_4Fe-4S_3 PF10588.4 KKK16084.1 - 3.5e-19 67.7 0.1 1.4e-18 65.8 0.1 2.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Fer2_4 PF13510.1 KKK16084.1 - 1.6e-15 56.6 0.1 5.4e-15 54.9 0.1 2.0 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain DUF1982 PF09326.6 KKK16084.1 - 2.7e-10 40.2 2.5 8.2e-09 35.4 0.0 2.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1982) Fer2 PF00111.22 KKK16084.1 - 0.00016 21.3 0.3 0.00016 21.3 0.2 2.2 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain TPP_enzyme_M PF00205.17 KKK16084.1 - 0.0078 15.9 0.3 0.11 12.3 0.0 2.6 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, central domain Fer4_6 PF12837.2 KKK16084.1 - 0.29 11.0 2.4 0.47 10.4 0.6 2.2 2 0 0 2 2 2 0 4Fe-4S binding domain HLH PF00010.21 KKK16085.1 - 3.6e-16 58.6 0.3 7.3e-16 57.6 0.2 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain CTP_transf_1 PF01148.15 KKK16090.1 - 3.2e-14 53.2 8.6 2.2e-12 47.1 4.0 2.0 1 1 1 2 2 2 2 Cytidylyltransferase family DUF3984 PF13136.1 KKK16090.1 - 8.5 5.4 12.5 12 5.0 7.6 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3984) DEAD PF00270.24 KKK16091.1 - 3.1e-36 124.4 0.0 1.3e-35 122.4 0.0 2.0 1 1 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 KKK16091.1 - 1.9e-20 72.1 0.0 3.8e-20 71.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 KKK16091.1 - 1.5e-18 66.4 0.0 3.2e-18 65.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KKK16091.1 - 0.0043 16.9 0.2 0.021 14.6 0.0 2.2 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 KKK16091.1 - 0.027 14.6 0.0 1.1 9.4 0.0 3.1 3 0 0 3 3 3 0 AAA domain UvrD-helicase PF00580.16 KKK16091.1 - 0.079 12.2 3.0 3 7.0 0.0 2.2 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain DUF1289 PF06945.8 KKK16091.1 - 2.4 7.7 5.7 0.53 9.7 1.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1289) His_Phos_1 PF00300.17 KKK16125.1 - 1.3e-11 44.8 0.7 2e-11 44.2 0.0 1.6 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) DUF4528 PF15031.1 KKK16125.1 - 0.029 14.0 0.1 0.073 12.8 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4528) Homeobox PF00046.24 KKK16126.1 - 9.1e-17 60.4 3.0 2.1e-16 59.2 1.7 1.9 2 0 0 2 2 2 1 Homeobox domain Homeobox_KN PF05920.6 KKK16126.1 - 2.1e-06 27.3 5.7 2.2e-06 27.2 0.2 2.6 2 0 0 2 2 2 1 Homeobox KN domain CDC45 PF02724.9 KKK16126.1 - 2.4 6.0 12.4 3.5 5.5 8.6 1.1 1 0 0 1 1 1 0 CDC45-like protein eIF-3c_N PF05470.7 KKK16126.1 - 9.9 4.1 11.7 15 3.5 8.1 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus CRC_subunit PF08624.5 KKK16128.1 - 3.6e-54 182.4 0.0 5.2e-54 181.9 0.0 1.2 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit Flavin_Reduct PF01613.13 KKK16145.1 - 1.8e-26 92.8 0.5 4.2e-20 72.1 0.5 2.4 2 0 0 2 2 2 2 Flavin reductase like domain SR-25 PF10500.4 KKK16145.1 - 0.66 9.4 3.8 0.29 10.5 0.7 1.8 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Vps5 PF09325.5 KKK16146.1 - 1.2e-89 299.6 3.1 2e-89 298.9 2.2 1.3 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.19 KKK16146.1 - 5.1e-25 87.4 0.0 1.1e-24 86.3 0.0 1.6 1 0 0 1 1 1 1 PX domain His_Phos_2 PF00328.17 KKK16146.1 - 0.017 14.4 0.6 0.028 13.7 0.4 1.3 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) Calreticulin PF00262.13 KKK16148.1 - 5.1e-161 535.3 15.4 5.1e-161 535.3 10.7 1.4 2 0 0 2 2 2 1 Calreticulin family IL13 PF03487.8 KKK16148.1 - 0.88 9.3 2.9 1.5 8.5 0.7 2.1 2 0 0 2 2 2 0 Interleukin-13 Aldolase_II PF00596.16 KKK16149.1 - 9.9e-42 142.6 0.0 1.2e-41 142.3 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Cyclin PF08613.6 KKK16152.1 - 4e-15 56.5 0.0 5.5e-15 56.0 0.0 1.2 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 KKK16152.1 - 0.00082 18.9 0.0 0.0015 18.1 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Nodulin_late PF07127.6 KKK16154.1 - 0.016 15.3 1.7 0.016 15.3 1.2 4.8 5 0 0 5 5 5 0 Late nodulin protein WAP PF00095.16 KKK16154.1 - 0.71 9.8 36.2 4.8 7.2 0.6 4.4 3 1 1 4 4 4 0 WAP-type (Whey Acidic Protein) 'four-disulfide core' Alpha-amylase PF00128.19 KKK16155.1 - 1e-94 317.5 1.5 1.7e-94 316.7 1.1 1.3 1 0 0 1 1 1 1 Alpha amylase, catalytic domain hDGE_amylase PF14701.1 KKK16155.1 - 0.0021 17.0 0.0 0.0034 16.3 0.0 1.2 1 0 0 1 1 1 1 glucanotransferase domain of human glycogen debranching enzyme TPT PF03151.11 KKK16157.1 - 1.7e-07 31.0 14.2 1.9e-07 30.8 8.2 2.2 1 1 1 2 2 2 1 Triose-phosphate Transporter family Glyco_transf_25 PF01755.12 KKK16157.1 - 0.013 15.1 0.0 1.3 8.6 0.0 2.4 2 0 0 2 2 2 0 Glycosyltransferase family 25 (LPS biosynthesis protein) EamA PF00892.15 KKK16157.1 - 0.016 15.2 1.9 0.016 15.2 1.3 3.1 3 0 0 3 3 3 0 EamA-like transporter family Aldedh PF00171.17 KKK16158.1 - 4.7e-153 509.8 0.0 5.6e-153 509.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 KKK16158.1 - 0.038 12.7 0.1 0.062 12.0 0.1 1.2 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) DUF1266 PF06889.6 KKK16158.1 - 0.08 12.7 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1266) Pkinase PF00069.20 KKK16180.1 - 1.7e-43 148.6 0.0 2.7e-43 147.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK16180.1 - 1.1e-16 60.7 0.0 1.5e-15 56.9 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 KKK16180.1 - 0.046 12.5 0.0 0.071 11.8 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Stc1 PF12898.2 KKK16181.1 - 4e-22 78.0 4.3 6.7e-22 77.3 3.0 1.3 1 0 0 1 1 1 1 Stc1 domain RE_LlaMI PF09562.5 KKK16181.1 - 0.0042 16.2 0.1 0.0059 15.8 0.1 1.2 1 0 0 1 1 1 1 LlaMI restriction endonuclease FAM60A PF15396.1 KKK16181.1 - 0.042 13.5 1.2 0.2 11.3 1.3 1.7 2 0 0 2 2 2 0 Protein Family FAM60A zf-RING_5 PF14634.1 KKK16181.1 - 0.42 10.3 4.2 0.35 10.6 0.7 2.1 2 0 0 2 2 2 0 zinc-RING finger domain Amidase PF01425.16 KKK16182.1 - 9.8e-63 212.5 0.0 2.4e-53 181.5 0.0 2.2 1 1 1 2 2 2 2 Amidase Fungal_trans_2 PF11951.3 KKK16182.1 - 0.0031 16.1 0.0 0.0054 15.3 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Stn1 PF10451.4 KKK16183.1 - 7.8e-08 31.4 0.0 4.6e-05 22.3 0.0 2.1 2 0 0 2 2 2 2 Telomere regulation protein Stn1 DnaJ PF00226.26 KKK16185.1 - 5.8e-24 83.6 2.4 5.8e-24 83.6 1.7 2.0 2 0 0 2 2 2 1 DnaJ domain DltD_M PF04918.7 KKK16185.1 - 3.8 7.6 10.6 1 9.5 4.8 1.8 2 0 0 2 2 2 0 DltD central region STT3 PF02516.9 KKK16216.1 - 1.4e-131 439.7 37.9 1.4e-126 423.2 25.0 2.1 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit PCI_Csn8 PF10075.4 KKK16217.1 - 2.8e-29 101.7 0.0 3.1e-29 101.5 0.0 1.0 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 KKK16217.1 - 0.0039 16.7 0.1 0.0048 16.4 0.0 1.1 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PMT PF02366.13 KKK16218.1 - 2.9e-82 275.6 19.2 5.3e-82 274.8 13.3 1.4 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 KKK16218.1 - 1.9e-19 69.9 0.6 3.2e-19 69.2 0.4 1.3 1 0 0 1 1 1 1 MIR domain Lin-8 PF03353.10 KKK16219.1 - 0.89 8.7 7.4 0.083 12.1 0.8 1.9 1 1 1 2 2 2 0 Ras-mediated vulval-induction antagonist PRKCSH PF07915.8 KKK16220.1 - 3.2e-21 75.9 0.2 9.5e-21 74.4 0.2 1.9 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.1 KKK16220.1 - 0.012 15.1 0.2 0.17 11.3 0.2 2.2 1 1 0 1 1 1 0 Glucosidase II beta subunit-like protein Pirin PF02678.11 KKK16221.1 - 1.3e-30 105.4 0.1 3e-30 104.2 0.1 1.6 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.8 KKK16221.1 - 1.7e-23 82.6 0.0 7.5e-23 80.5 0.0 1.9 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.6 KKK16221.1 - 4.4e-05 22.9 2.1 0.0001 21.7 0.8 2.1 2 0 0 2 2 2 1 Cupin domain APH PF01636.18 KKK16222.1 - 3e-13 50.0 0.0 1.3e-12 48.0 0.0 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.6 KKK16222.1 - 0.0045 15.6 0.0 0.15 10.7 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1679) Coiled-coil_56 PF09813.4 KKK16223.1 - 5e-05 23.2 0.0 5.7e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 56 MFS_1 PF07690.11 KKK16224.1 - 8.5e-35 120.0 34.6 1.1e-34 119.7 24.0 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KKK16224.1 - 2.4e-08 33.0 22.5 2.4e-07 29.6 15.6 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter DUF3453 PF11935.3 KKK16225.1 - 6.6e-75 251.5 0.0 1.2e-74 250.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3453) RNA_pol_Rbc25 PF08292.7 KKK16226.1 - 5e-35 120.3 0.0 7.2e-35 119.8 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.12 KKK16226.1 - 5.5e-15 55.2 0.0 9.7e-15 54.4 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 Cys_Met_Meta_PP PF01053.15 KKK16227.1 - 1e-141 471.7 0.1 1.1e-141 471.5 0.1 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 KKK16227.1 - 2.5e-08 33.2 0.2 4.8e-08 32.3 0.2 1.4 1 1 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 KKK16227.1 - 9.6e-08 31.4 0.4 1.6e-07 30.7 0.3 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.14 KKK16227.1 - 1.1e-07 30.9 0.5 2e-07 30.0 0.3 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 KKK16227.1 - 5.5e-05 22.4 0.1 0.00013 21.2 0.1 1.7 1 1 0 1 1 1 1 Beta-eliminating lyase RRM_1 PF00076.17 KKK16228.1 - 1.8e-09 37.0 0.0 4.5e-06 26.2 0.0 3.0 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KKK16228.1 - 1.1e-08 34.7 0.0 0.0026 17.5 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KKK16228.1 - 8.6e-07 28.8 0.0 0.00044 20.1 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) dNK PF01712.14 KKK16228.1 - 0.026 14.4 6.8 0.063 13.1 4.7 1.6 1 0 0 1 1 1 0 Deoxynucleoside kinase Ycf1 PF05758.7 KKK16228.1 - 1.2 6.7 8.1 1.8 6.2 5.6 1.3 1 0 0 1 1 1 0 Ycf1 Sds3 PF08598.6 KKK16229.1 - 1.9e-24 86.3 2.1 1.9e-24 86.3 1.5 2.6 2 2 0 2 2 2 1 Sds3-like VIT_2 PF13757.1 KKK16229.1 - 0.022 14.2 0.0 0.043 13.2 0.0 1.4 1 0 0 1 1 1 0 Vault protein inter-alpha-trypsin domain DUF1487 PF07368.6 KKK16229.1 - 0.024 13.8 0.4 1.5 7.9 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1487) ATP-synt_E PF05680.7 KKK16230.1 - 6.7e-21 74.0 0.4 7e-21 73.9 0.3 1.1 1 0 0 1 1 1 1 ATP synthase E chain UCR_14kD PF02271.11 KKK16230.1 - 0.063 13.0 0.0 0.065 13.0 0.0 1.1 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase complex 14kD subunit WD40 PF00400.27 KKK16231.1 - 3.1e-18 64.8 4.4 3e-05 23.7 0.0 5.9 6 1 0 6 6 6 4 WD domain, G-beta repeat GPI-anchored PF10342.4 KKK16232.1 - 3e-20 72.5 4.3 3e-20 72.5 3.0 2.7 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family TFIIA PF03153.8 KKK16232.1 - 0.33 10.7 3.1 0.34 10.7 2.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAP1 PF08601.5 KKK16232.1 - 1.4 8.4 11.7 1.7 8.2 8.1 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 Macoilin PF09726.4 KKK16232.1 - 4.8 5.3 13.0 5.4 5.1 9.0 1.0 1 0 0 1 1 1 0 Transmembrane protein NUFIP1 PF10453.4 KKK16233.1 - 3.6e-19 68.0 2.2 3.6e-19 68.0 1.5 3.0 2 0 0 2 2 2 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) zf-CCCH PF00642.19 KKK16233.1 - 1.7e-07 30.7 2.4 3.1e-07 29.9 1.6 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Pyr_redox_3 PF13738.1 KKK16235.1 - 4.4e-30 105.2 0.0 7.1e-30 104.5 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KKK16235.1 - 2.3e-08 34.1 0.0 2.3e-07 30.9 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KKK16235.1 - 1.1e-05 25.3 0.3 0.0016 18.2 0.3 2.9 2 1 0 2 2 2 1 FAD-NAD(P)-binding K_oxygenase PF13434.1 KKK16235.1 - 2.6e-05 23.3 0.0 0.00045 19.2 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) PAP2_3 PF14378.1 KKK16236.1 - 1.1e-21 77.2 10.1 1.4e-10 41.0 0.1 3.8 3 1 0 3 3 3 3 PAP2 superfamily PAP2 PF01569.16 KKK16236.1 - 0.014 15.0 5.6 0.072 12.7 3.9 2.2 1 1 0 1 1 1 0 PAP2 superfamily Fungal_trans PF04082.13 KKK16237.1 - 5.8e-17 61.4 0.0 9.6e-17 60.7 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK16237.1 - 3.3e-06 26.8 13.5 7e-06 25.8 9.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Methyltransf_16 PF10294.4 KKK16239.1 - 4e-06 26.3 0.0 0.00036 20.0 0.0 2.2 2 0 0 2 2 2 2 Putative methyltransferase Methyltransf_31 PF13847.1 KKK16239.1 - 0.067 12.7 0.0 4.4 6.8 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_25 PF13649.1 KKK16239.1 - 0.13 12.6 0.0 4.3 7.7 0.0 2.4 1 1 0 1 1 1 0 Methyltransferase domain SHD1 PF03983.7 KKK16240.1 - 3.9e-36 122.5 0.1 7.1e-36 121.6 0.0 1.4 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_1 PF00018.23 KKK16240.1 - 2.4e-34 116.4 6.2 9.2e-12 44.1 0.1 4.3 4 0 0 4 4 4 3 SH3 domain SH3_9 PF14604.1 KKK16240.1 - 2.6e-30 103.7 7.9 1.3e-12 47.1 0.1 4.2 4 0 0 4 4 4 3 Variant SH3 domain SH3_2 PF07653.12 KKK16240.1 - 6e-22 76.8 0.2 8.8e-09 34.7 0.0 4.4 4 0 0 4 4 4 4 Variant SH3 domain DUF1720 PF08226.6 KKK16240.1 - 0.00045 20.2 21.8 0.00045 20.2 15.1 5.9 1 1 3 5 5 5 2 Domain of unknown function (DUF1720) SH3_3 PF08239.6 KKK16240.1 - 0.0011 19.0 5.6 0.26 11.5 0.6 2.8 3 0 0 3 3 3 2 Bacterial SH3 domain Ank_2 PF12796.2 KKK16242.1 - 2.8e-59 197.4 18.9 3.7e-13 49.6 0.1 6.1 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 KKK16242.1 - 5.4e-54 177.4 4.0 1.1e-06 28.1 0.0 9.9 10 0 0 10 10 10 9 Ankyrin repeat Ank_4 PF13637.1 KKK16242.1 - 1.3e-42 143.4 15.4 4.2e-09 36.6 0.0 10.2 5 2 6 11 11 11 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 KKK16242.1 - 5.9e-40 131.3 3.4 3.4e-05 23.6 0.0 10.7 11 0 0 11 11 11 7 Ankyrin repeat Ank_5 PF13857.1 KKK16242.1 - 3.4e-33 112.9 13.5 4.7e-07 29.8 0.0 8.4 5 3 3 8 8 8 7 Ankyrin repeats (many copies) Ank PF00023.25 KKK16243.1 - 2.9e-10 39.4 0.1 1.6e-07 30.7 0.0 3.3 2 1 0 2 2 2 1 Ankyrin repeat NACHT PF05729.7 KKK16243.1 - 6.3e-10 38.9 0.0 2.7e-09 36.9 0.0 2.1 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.1 KKK16243.1 - 4e-09 36.7 0.0 1e-08 35.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain Ank_2 PF12796.2 KKK16243.1 - 8.3e-09 35.6 0.0 2e-08 34.4 0.0 1.7 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 KKK16243.1 - 1.7e-07 30.7 0.0 1.6e-06 27.7 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeat AAA_16 PF13191.1 KKK16243.1 - 9.2e-07 29.0 0.0 2.9e-06 27.4 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain Ank_4 PF13637.1 KKK16243.1 - 3.3e-06 27.4 0.0 3.5e-05 24.1 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 KKK16243.1 - 2.3e-05 24.4 0.0 0.0001 22.4 0.0 2.2 1 1 0 1 1 1 1 Ankyrin repeats (many copies) NB-ARC PF00931.17 KKK16243.1 - 0.00045 19.1 0.3 0.0017 17.2 0.2 1.8 1 1 0 1 1 1 1 NB-ARC domain AAA_33 PF13671.1 KKK16243.1 - 0.0055 16.5 0.0 0.015 15.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 KKK16243.1 - 0.033 14.3 0.0 0.11 12.7 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Torsin PF06309.6 KKK16243.1 - 0.064 13.1 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 Torsin DUF87 PF01935.12 KKK16243.1 - 0.13 12.0 1.0 2.2 8.0 0.1 2.3 1 1 1 2 2 2 0 Domain of unknown function DUF87 SAM_2 PF07647.12 KKK16246.1 - 3.5e-11 42.7 0.1 6.6e-11 41.9 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 KKK16246.1 - 5.2e-09 36.1 0.2 1.3e-08 34.8 0.1 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH PF00169.24 KKK16246.1 - 4.3e-05 23.6 0.0 0.00012 22.2 0.0 1.8 1 0 0 1 1 1 1 PH domain Ste50p-SAM PF09235.5 KKK16246.1 - 0.00014 21.8 0.0 0.00029 20.7 0.0 1.5 1 0 0 1 1 1 1 Ste50p, sterile alpha motif SAM_PNT PF02198.11 KKK16246.1 - 0.0033 17.1 0.1 0.0086 15.8 0.0 1.7 2 0 0 2 2 2 1 Sterile alpha motif (SAM)/Pointed domain PH_11 PF15413.1 KKK16246.1 - 0.035 14.3 0.0 0.077 13.2 0.0 1.6 1 0 0 1 1 1 0 Pleckstrin homology domain Fungal_trans_2 PF11951.3 KKK16247.1 - 6.7e-84 281.6 0.2 7.9e-84 281.4 0.2 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain ASFV_J13L PF05568.6 KKK16247.1 - 1.8 8.0 15.3 3.2 7.2 10.6 1.3 1 0 0 1 1 1 0 African swine fever virus J13L protein PH_10 PF15411.1 KKK16248.1 - 7e-25 87.4 0.1 1.2e-24 86.6 0.1 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain VWA_3 PF13768.1 KKK16248.1 - 1.7e-11 44.0 0.0 8.2e-11 41.8 0.0 2.1 2 1 0 2 2 2 1 von Willebrand factor type A domain zf-RING_2 PF13639.1 KKK16248.1 - 3.9e-08 33.0 5.1 7.3e-08 32.1 3.6 1.5 1 0 0 1 1 1 1 Ring finger domain VWA PF00092.23 KKK16248.1 - 2.8e-07 30.4 0.0 5.2e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain zf-RING_5 PF14634.1 KKK16248.1 - 0.00015 21.4 3.9 0.00026 20.6 2.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KKK16248.1 - 0.00079 19.4 4.0 0.0014 18.5 2.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KKK16248.1 - 0.0061 16.6 1.1 0.012 15.7 0.8 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 KKK16248.1 - 0.0062 16.1 4.2 0.011 15.3 2.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.6 KKK16248.1 - 0.053 13.5 4.5 0.098 12.6 3.1 1.4 1 0 0 1 1 1 0 RING-like domain zf-UDP PF14569.1 KKK16248.1 - 0.24 11.1 1.2 0.49 10.1 0.8 1.4 1 0 0 1 1 1 0 Zinc-binding RING-finger Ribosomal_S17e PF00833.13 KKK16265.1 - 1.2e-36 125.1 0.1 1.2e-36 125.0 0.1 1.0 1 0 0 1 1 1 1 Ribosomal S17 Cryptochrome_C PF12546.3 KKK16265.1 - 0.11 13.1 0.0 0.13 12.9 0.0 1.2 1 0 0 1 1 1 0 Blue/Ultraviolet sensing protein C terminal GMC_oxred_N PF00732.14 KKK16266.1 - 1.5e-61 208.1 0.0 2e-61 207.7 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KKK16266.1 - 3.8e-38 131.0 0.1 6.8e-38 130.1 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 KKK16266.1 - 4e-07 29.2 0.0 0.0087 14.9 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 KKK16266.1 - 0.00021 20.2 1.7 0.0012 17.8 1.2 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KKK16266.1 - 0.0065 15.4 0.0 0.01 14.7 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 KKK16266.1 - 0.011 15.6 0.1 0.042 13.8 0.1 2.0 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KKK16266.1 - 0.042 14.2 0.4 13 6.2 0.1 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase MFS_1 PF07690.11 KKK16267.1 - 2.9e-42 144.6 44.6 2.9e-42 144.6 30.9 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KKK16267.1 - 1.1e-09 37.4 14.5 1.1e-09 37.4 10.0 2.3 2 1 0 2 2 2 1 Sugar (and other) transporter Abhydrolase_3 PF07859.8 KKK16268.1 - 3.2e-24 85.6 0.1 4.6e-24 85.1 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 KKK16268.1 - 1.3e-17 63.4 0.0 1.9e-17 63.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 KKK16268.1 - 1.7e-05 24.6 0.0 2.4e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KKK16268.1 - 0.021 14.0 0.0 0.08 12.1 0.0 1.8 2 0 0 2 2 2 0 Prolyl oligopeptidase family zf-CCCH PF00642.19 KKK16269.1 - 6.2e-06 25.7 13.7 0.00036 20.1 0.7 3.6 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Dor1 PF04124.7 KKK16269.1 - 0.1 11.0 0.3 0.16 10.3 0.2 1.1 1 0 0 1 1 1 0 Dor1-like family Rubrerythrin PF02915.12 KKK16269.1 - 0.47 10.7 2.9 5.4 7.3 2.0 2.1 1 1 0 1 1 1 0 Rubrerythrin ketoacyl-synt PF00109.21 KKK16270.1 - 2.9e-68 230.1 0.0 6e-68 229.0 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 KKK16270.1 - 4.2e-62 209.0 0.4 9.5e-62 207.8 0.3 1.7 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.16 KKK16270.1 - 3.7e-57 194.0 0.4 7e-56 189.8 0.0 2.7 2 1 0 2 2 2 1 Acyl transferase domain PS-DH PF14765.1 KKK16270.1 - 7.1e-56 189.5 0.0 1.2e-55 188.8 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 KKK16270.1 - 7.6e-47 159.3 0.2 2.2e-46 157.8 0.1 1.9 1 0 0 1 1 1 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 KKK16270.1 - 9.9e-40 135.1 0.0 2.6e-39 133.7 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 KKK16270.1 - 8.2e-07 28.6 0.0 2.2e-06 27.2 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_31 PF13847.1 KKK16270.1 - 1.5e-06 27.9 0.0 4.8e-06 26.2 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 KKK16270.1 - 2.4e-06 27.3 0.0 6.5e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KKK16270.1 - 0.0001 22.7 0.0 0.00032 21.1 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.18 KKK16270.1 - 0.00066 18.7 0.3 0.0012 17.8 0.2 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain PP-binding PF00550.20 KKK16270.1 - 0.0015 18.7 0.1 0.009 16.2 0.0 2.4 2 0 0 2 2 2 1 Phosphopantetheine attachment site ADH_N PF08240.7 KKK16270.1 - 0.0021 17.8 0.0 0.0066 16.2 0.0 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Ubie_methyltran PF01209.13 KKK16270.1 - 0.0062 15.6 0.0 0.012 14.7 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.7 KKK16270.1 - 0.017 15.5 0.0 0.059 13.8 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain YflT PF11181.3 KKK16270.1 - 0.18 11.9 0.0 1 9.5 0.0 2.3 2 0 0 2 2 2 0 Heat induced stress protein YflT DUF1212 PF06738.7 KKK16271.1 - 3.4e-56 189.7 16.4 1.5e-50 171.3 0.1 2.9 3 0 0 3 3 3 2 Protein of unknown function (DUF1212) DUF3815 PF12821.2 KKK16271.1 - 5.4e-28 97.5 10.4 5.4e-28 97.5 7.2 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF3815) ABC2_membrane PF01061.19 KKK16272.1 - 9.7e-91 302.5 45.0 6.2e-49 166.0 12.6 2.6 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.22 KKK16272.1 - 6.9e-39 133.2 0.0 2e-18 67.0 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 KKK16272.1 - 1.1e-29 102.0 5.2 4.5e-28 96.9 0.0 3.1 3 0 0 3 3 2 1 CDR ABC transporter ABC2_membrane_3 PF12698.2 KKK16272.1 - 1.3e-06 27.7 38.3 0.0004 19.5 12.3 2.4 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_25 PF13481.1 KKK16272.1 - 2.2e-06 27.2 0.1 0.0049 16.2 0.1 2.5 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 KKK16272.1 - 4.5e-06 26.8 0.0 0.074 13.2 0.0 3.2 2 1 0 2 2 2 2 AAA domain AAA_17 PF13207.1 KKK16272.1 - 6.3e-05 23.7 0.0 0.6 10.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain ABC_trans_N PF14510.1 KKK16272.1 - 0.00011 22.2 0.1 0.00027 20.9 0.1 1.6 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_16 PF13191.1 KKK16272.1 - 0.00026 21.0 0.3 0.1 12.5 0.1 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.1 KKK16272.1 - 0.00046 20.0 0.0 1.1 9.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.1 KKK16272.1 - 0.00083 19.3 0.9 0.38 10.6 0.3 2.5 2 0 0 2 2 2 1 AAA domain PduV-EutP PF10662.4 KKK16272.1 - 0.00088 18.7 0.8 1.3 8.5 0.0 2.4 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation cobW PF02492.14 KKK16272.1 - 0.0012 18.3 1.4 0.4 10.1 0.3 2.4 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.1 KKK16272.1 - 0.0015 18.0 0.5 0.077 12.5 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF258 PF03193.11 KKK16272.1 - 0.0019 17.4 0.0 0.018 14.2 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_18 PF13238.1 KKK16272.1 - 0.0022 18.3 0.0 1.4 9.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KKK16272.1 - 0.0047 16.6 0.1 2.1 8.1 0.0 2.6 2 0 0 2 2 2 1 Part of AAA domain NACHT PF05729.7 KKK16272.1 - 0.0049 16.5 0.8 3.1 7.4 0.1 2.4 2 0 0 2 2 2 2 NACHT domain AAA_10 PF12846.2 KKK16272.1 - 0.018 14.4 0.3 0.72 9.2 0.0 2.4 2 0 0 2 2 2 0 AAA-like domain AAA_21 PF13304.1 KKK16272.1 - 0.03 14.3 0.0 2.1 8.2 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA PF00004.24 KKK16272.1 - 0.044 13.9 0.0 8.8 6.5 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 KKK16272.1 - 0.046 13.4 0.0 5.3 6.6 0.0 2.4 2 0 0 2 2 2 0 Archaeal ATPase UPF0079 PF02367.12 KKK16272.1 - 0.063 12.9 0.5 5.7 6.5 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 MobB PF03205.9 KKK16272.1 - 0.12 12.0 0.1 21 4.8 0.1 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Miro PF08477.8 KKK16272.1 - 0.13 12.7 0.0 4.1 7.9 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein SbcCD_C PF13558.1 KKK16272.1 - 0.13 12.1 0.0 1.7 8.5 0.0 2.5 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit CorA PF01544.13 KKK16273.1 - 6.1e-08 32.0 2.5 1.1e-07 31.2 1.7 1.5 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein TF_AP-2 PF03299.9 KKK16273.1 - 0.032 13.7 0.1 0.049 13.1 0.1 1.2 1 0 0 1 1 1 0 Transcription factor AP-2 Xan_ur_permease PF00860.15 KKK16276.1 - 2.1e-23 82.4 30.7 1.1e-14 53.8 9.8 2.9 3 0 0 3 3 3 2 Permease family Zn_clus PF00172.13 KKK16277.1 - 1.3e-07 31.4 9.1 2.6e-07 30.4 6.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KKK16277.1 - 0.00045 19.1 0.0 0.0011 17.8 0.0 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pox_F11 PF04943.7 KKK16300.1 - 0.3 9.9 0.1 0.48 9.2 0.1 1.2 1 0 0 1 1 1 0 Poxvirus F11 protein Fungal_trans PF04082.13 KKK16301.1 - 2e-18 66.2 0.1 4.6e-18 65.0 0.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK16301.1 - 3e-07 30.2 12.1 5.3e-07 29.4 8.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FCH PF00611.18 KKK16302.1 - 7.8e-21 74.0 0.0 6.4e-20 71.1 0.0 2.5 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.23 KKK16302.1 - 2.2e-12 46.1 0.0 4.9e-12 45.0 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KKK16302.1 - 8.3e-11 41.3 0.0 2.3e-10 39.8 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 KKK16302.1 - 2.6e-10 39.6 0.0 9e-10 37.9 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain Not1 PF04054.10 KKK16303.1 - 3.6e-140 467.1 0.1 8e-140 465.9 0.0 1.6 1 0 0 1 1 1 1 CCR4-Not complex component, Not1 DUF3819 PF12842.2 KKK16303.1 - 2.3e-51 173.3 2.7 4.5e-51 172.4 0.6 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3819) Leuk-A4-hydro_C PF09127.6 KKK16303.1 - 0.051 13.1 0.1 0.22 11.0 0.1 2.2 2 0 0 2 2 2 0 Leukotriene A4 hydrolase, C-terminal Seipin PF06775.9 KKK16304.1 - 2.3e-66 223.1 2.4 3.2e-66 222.6 1.6 1.2 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) Trypan_PARP PF05887.6 KKK16304.1 - 0.36 10.6 4.0 0.56 10.0 2.8 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) TTL PF03133.10 KKK16305.1 - 3e-56 190.5 0.0 4.6e-56 189.9 0.0 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family SurE PF01975.12 KKK16305.1 - 3.3e-42 144.0 0.0 4.9e-42 143.4 0.0 1.3 1 0 0 1 1 1 1 Survival protein SurE ATPgrasp_YheCD PF14398.1 KKK16305.1 - 5.4e-05 22.1 0.0 0.0012 17.6 0.0 2.2 2 0 0 2 2 2 1 YheC/D like ATP-grasp ATP-grasp_4 PF13535.1 KKK16305.1 - 0.0011 18.7 0.1 0.059 13.0 0.0 2.3 2 0 0 2 2 2 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 KKK16305.1 - 0.068 12.5 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus Glyco_transf_28 PF03033.15 KKK16305.1 - 0.12 12.0 0.0 0.32 10.7 0.0 1.6 1 1 0 1 1 1 0 Glycosyltransferase family 28 N-terminal domain ATP-grasp_3 PF02655.9 KKK16305.1 - 0.14 12.0 0.0 11 5.8 0.0 2.3 2 0 0 2 2 2 0 ATP-grasp domain Methyltransf_23 PF13489.1 KKK16307.1 - 1.3e-28 99.7 0.0 1.8e-28 99.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KKK16307.1 - 1.7e-06 28.3 0.0 5.8e-06 26.7 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KKK16307.1 - 3.3e-05 24.2 0.0 0.0042 17.5 0.0 3.1 1 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 KKK16307.1 - 6e-05 23.3 0.0 0.00012 22.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KKK16307.1 - 0.00017 22.1 0.0 0.00052 20.5 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KKK16307.1 - 0.0032 17.4 0.1 0.0064 16.5 0.1 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KKK16307.1 - 0.0032 17.0 0.0 0.02 14.4 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Pex14_N PF04695.8 KKK16308.1 - 3.7e-43 146.8 0.0 3.7e-43 146.8 0.0 4.1 2 1 1 3 3 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region TFIIA PF03153.8 KKK16308.1 - 0.00024 21.1 12.1 0.00024 21.1 8.4 2.5 2 1 1 3 3 3 1 Transcription factor IIA, alpha/beta subunit IncA PF04156.9 KKK16308.1 - 0.082 12.4 0.0 0.082 12.4 0.0 2.9 3 0 0 3 3 3 0 IncA protein TRADD_N PF09034.5 KKK16308.1 - 0.086 12.8 1.1 0.17 11.9 0.7 1.4 1 0 0 1 1 1 0 TRADD, N-terminal domain Nucleoplasmin PF03066.10 KKK16308.1 - 0.13 11.8 10.6 0.33 10.4 7.3 1.6 1 0 0 1 1 1 0 Nucleoplasmin Baculo_PEP_C PF04513.7 KKK16308.1 - 0.15 11.8 2.6 0.52 10.1 1.9 1.8 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF244 PF03112.9 KKK16308.1 - 0.63 9.5 2.8 0.48 9.9 0.3 1.9 2 0 0 2 2 2 0 Uncharacterized protein family (ORF7) DUF Ndc80_HEC PF03801.8 KKK16309.1 - 4e-63 211.6 0.4 1.1e-62 210.2 0.0 1.9 2 0 0 2 2 2 1 HEC/Ndc80p family Filament PF00038.16 KKK16309.1 - 0.00056 19.4 45.5 0.00099 18.6 14.1 2.6 2 0 0 2 2 2 2 Intermediate filament protein HSBP1 PF06825.7 KKK16309.1 - 0.004 16.6 2.3 0.32 10.5 0.2 3.8 3 1 0 3 3 3 1 Heat shock factor binding protein 1 CENP-F_leu_zip PF10473.4 KKK16309.1 - 0.012 15.4 14.7 0.012 15.4 10.2 4.1 2 2 2 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF869 PF05911.6 KKK16309.1 - 0.16 10.1 37.3 0.047 11.9 10.9 2.2 2 0 0 2 2 2 0 Plant protein of unknown function (DUF869) NPV_P10 PF05531.7 KKK16309.1 - 2.1 8.6 14.7 3.4 7.9 0.3 4.4 2 2 2 4 4 4 0 Nucleopolyhedrovirus P10 protein HSP70 PF00012.15 KKK16309.1 - 3.4 5.4 31.6 0.14 10.0 10.3 2.6 2 1 1 3 3 3 0 Hsp70 protein Tropomyosin_1 PF12718.2 KKK16309.1 - 4 7.2 61.3 0.067 13.0 13.3 4.8 2 2 3 5 5 5 0 Tropomyosin like Reo_sigmaC PF04582.7 KKK16309.1 - 4.1 6.5 8.1 0.31 10.1 0.9 2.2 2 1 0 2 2 2 0 Reovirus sigma C capsid protein APG6 PF04111.7 KKK16309.1 - 6.2 5.7 48.7 0.073 12.0 10.6 3.3 2 1 1 3 3 3 0 Autophagy protein Apg6 zf-primase PF09329.6 KKK16311.1 - 2.2e-19 68.7 0.7 3.9e-19 67.9 0.5 1.4 1 0 0 1 1 1 1 Primase zinc finger RNase_H2-Ydr279 PF09468.5 KKK16312.1 - 6.5e-102 340.8 1.7 8.4e-102 340.4 1.2 1.1 1 0 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) SnAPC_2_like PF11035.3 KKK16312.1 - 0.032 13.7 6.5 0.062 12.7 4.5 1.5 1 0 0 1 1 1 0 Small nuclear RNA activating complex subunit 2-like GalKase_gal_bdg PF10509.4 KKK16313.1 - 1.4e-19 69.1 0.1 2.4e-19 68.3 0.0 1.4 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.21 KKK16313.1 - 2.8e-15 56.1 0.7 9.5e-15 54.4 0.5 1.9 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 KKK16313.1 - 4.3e-12 46.0 0.0 9.3e-12 44.9 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal HTH_37 PF13744.1 KKK16313.1 - 0.05 13.4 0.1 0.24 11.2 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_3 PF01381.17 KKK16313.1 - 0.12 12.2 0.2 0.63 9.9 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix TPP_enzyme_N PF02776.13 KKK16314.1 - 1.1e-57 194.2 0.1 3e-56 189.6 0.0 2.6 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 KKK16314.1 - 7.3e-50 168.5 0.1 1.1e-47 161.3 0.0 3.1 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 KKK16314.1 - 3.2e-35 120.8 0.1 7.6e-35 119.6 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain POR_N PF01855.14 KKK16314.1 - 0.024 14.1 0.0 0.047 13.1 0.0 1.5 1 0 0 1 1 1 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg MRP-L28 PF09812.4 KKK16315.1 - 2.2e-07 30.8 0.1 3.6e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 RINGv PF12906.2 KKK16315.1 - 4e-05 23.5 6.9 6.9e-05 22.8 4.8 1.4 1 0 0 1 1 1 1 RING-variant domain FANCL_C PF11793.3 KKK16315.1 - 0.00016 21.5 3.3 0.00031 20.6 2.3 1.4 1 0 0 1 1 1 1 FANCL C-terminal domain zf-RING_2 PF13639.1 KKK16315.1 - 0.0039 16.9 5.3 0.0063 16.3 3.7 1.3 1 0 0 1 1 1 1 Ring finger domain Med3 PF11593.3 KKK16316.1 - 6.9 5.8 11.3 7.8 5.6 7.8 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DASH_Duo1 PF08651.5 KKK16317.1 - 3.1e-28 97.1 3.7 3.1e-28 97.1 2.6 1.7 2 0 0 2 2 2 1 DASH complex subunit Duo1 Tic20 PF09685.5 KKK16317.1 - 2.1e-07 30.9 1.8 3.3e-07 30.2 1.2 1.3 1 0 0 1 1 1 1 Tic20-like protein ARS2 PF04959.8 KKK16317.1 - 0.042 14.0 1.2 0.07 13.3 0.4 1.6 1 1 0 1 1 1 0 Arsenite-resistance protein 2 DUF4557 PF15101.1 KKK16317.1 - 0.28 10.9 5.0 0.61 9.8 3.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Dor1 PF04124.7 KKK16318.1 - 4.7e-52 176.5 3.5 4.2e-41 140.5 2.9 2.3 2 0 0 2 2 2 2 Dor1-like family Vps51 PF08700.6 KKK16318.1 - 0.00022 21.0 2.4 0.00026 20.7 0.3 2.2 2 0 0 2 2 2 1 Vps51/Vps67 COG2 PF06148.6 KKK16318.1 - 0.07 13.0 1.0 0.21 11.4 0.7 1.8 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF4328 PF14219.1 KKK16318.1 - 0.082 12.1 0.1 0.2 10.9 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4328) EAF PF09816.4 KKK16319.1 - 1.1e-24 86.4 0.5 2.5e-24 85.3 0.3 1.6 1 0 0 1 1 1 1 RNA polymerase II transcription elongation factor Cyclin_N PF00134.18 KKK16319.1 - 5.3e-16 58.3 0.1 1.6e-15 56.8 0.1 1.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 KKK16319.1 - 8.9e-08 32.0 2.1 5.1e-06 26.4 0.0 3.0 3 1 0 3 3 3 1 Cyclin, C-terminal domain TFIIB PF00382.14 KKK16319.1 - 0.0038 16.9 3.5 0.34 10.7 0.0 2.5 2 0 0 2 2 2 2 Transcription factor TFIIB repeat His_Phos_1 PF00300.17 KKK16320.1 - 5e-32 111.1 0.0 1.1e-31 110.0 0.0 1.6 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.17 KKK16320.1 - 0.00019 20.8 0.0 0.00036 19.9 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) TBP PF00352.16 KKK16321.1 - 4.5e-70 231.0 0.1 4.3e-35 118.9 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.3 KKK16321.1 - 0.00012 22.0 0.0 0.44 10.6 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) Pollen_allerg_2 PF01620.11 KKK16321.1 - 0.0064 16.8 0.1 0.0093 16.3 0.1 1.3 1 0 0 1 1 1 1 Ribonuclease (pollen allergen) DAO PF01266.19 KKK16322.1 - 1.7e-50 171.9 0.1 2e-50 171.6 0.1 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 KKK16322.1 - 5.7e-07 28.7 0.0 3e-06 26.3 0.0 1.9 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.9 KKK16322.1 - 1.3e-06 28.4 0.0 0.00013 21.9 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KKK16322.1 - 1.5e-06 28.0 0.2 0.028 14.1 0.1 2.6 2 0 0 2 2 2 2 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 KKK16322.1 - 3.3e-06 26.2 0.0 0.00069 18.6 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein FAD_binding_2 PF00890.19 KKK16322.1 - 1.2e-05 24.3 0.0 0.016 14.1 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain Trp_halogenase PF04820.9 KKK16322.1 - 3.7e-05 22.5 0.0 0.085 11.4 0.0 2.2 2 0 0 2 2 2 2 Tryptophan halogenase NAD_binding_8 PF13450.1 KKK16322.1 - 8e-05 22.5 0.0 0.0002 21.2 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KKK16322.1 - 0.00035 20.9 0.1 0.0025 18.1 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 KKK16322.1 - 0.0061 15.6 0.0 1.3 7.9 0.0 2.4 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.1 KKK16322.1 - 0.013 15.5 0.1 0.98 9.4 0.0 2.6 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KKK16322.1 - 0.021 13.3 0.1 4.1 5.7 0.1 2.2 2 0 0 2 2 2 0 HI0933-like protein GMC_oxred_N PF00732.14 KKK16322.1 - 0.024 13.7 0.0 0.17 10.9 0.0 2.0 2 0 0 2 2 2 0 GMC oxidoreductase FAD_binding_3 PF01494.14 KKK16322.1 - 0.027 13.5 0.1 0.34 9.8 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain Thi4 PF01946.12 KKK16322.1 - 0.1 11.6 0.0 0.29 10.2 0.0 1.6 2 0 0 2 2 2 0 Thi4 family TrkA_N PF02254.13 KKK16322.1 - 0.12 12.3 0.0 0.3 11.0 0.0 1.7 2 0 0 2 2 1 0 TrkA-N domain DUF3439 PF11921.3 KKK16322.1 - 1.8 8.2 8.5 3.5 7.4 5.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) FolB PF02152.13 KKK16323.1 - 1.7e-23 82.9 0.0 7.6e-20 71.1 0.0 2.4 2 0 0 2 2 2 2 Dihydroneopterin aldolase ETF_QO PF05187.8 KKK16324.1 - 4.4e-45 152.1 0.0 7.5e-45 151.4 0.0 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase RRM_1 PF00076.17 KKK16324.1 - 8.3e-18 63.8 0.0 9.7e-08 31.5 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KKK16324.1 - 1e-12 47.7 0.0 4.4e-06 26.4 0.0 2.7 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KKK16324.1 - 7.2e-11 41.9 0.0 0.00016 21.6 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DAO PF01266.19 KKK16324.1 - 8e-09 34.8 0.1 0.00056 18.9 0.1 2.5 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KKK16324.1 - 1.5e-07 30.5 0.3 0.0031 16.4 0.5 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 KKK16324.1 - 2.2e-07 30.7 0.0 8.9e-07 28.8 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 KKK16324.1 - 6e-05 22.2 0.0 0.00012 21.3 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KKK16324.1 - 0.00014 21.8 0.0 0.00023 21.0 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KKK16324.1 - 0.00032 19.8 0.0 0.015 14.4 0.0 2.1 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.9 KKK16324.1 - 0.00032 19.3 0.4 0.00053 18.5 0.3 1.3 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_3 PF01494.14 KKK16324.1 - 0.00076 18.6 0.0 0.0016 17.5 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 KKK16324.1 - 0.0011 19.0 0.0 0.0023 18.0 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KKK16324.1 - 0.003 17.3 0.0 0.0072 16.1 0.0 1.7 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox PF00070.22 KKK16324.1 - 0.0073 16.6 0.1 8.5 6.8 0.0 2.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KKK16324.1 - 0.033 13.1 0.3 0.049 12.5 0.2 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Trp_halogenase PF04820.9 KKK16324.1 - 0.068 11.7 0.0 0.22 10.1 0.1 1.7 2 0 0 2 2 2 0 Tryptophan halogenase GIDA PF01134.17 KKK16324.1 - 0.19 10.5 0.4 0.29 9.9 0.3 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Hexokinase_2 PF03727.11 KKK16332.1 - 3.1e-36 124.7 0.0 4.9e-28 97.9 0.0 2.2 1 1 1 2 2 2 2 Hexokinase Hexokinase_1 PF00349.16 KKK16332.1 - 5.6e-36 123.8 0.0 8.2e-36 123.2 0.0 1.2 1 0 0 1 1 1 1 Hexokinase DUF840 PF05801.6 KKK16332.1 - 0.14 12.3 0.0 6.8 6.8 0.0 2.7 3 0 0 3 3 3 0 Lagovirus protein of unknown function (DUF840) Arylsulfotran_2 PF14269.1 KKK16333.1 - 1.9e-48 165.1 0.2 2.8e-48 164.6 0.2 1.1 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.6 KKK16333.1 - 7.1e-13 47.8 0.5 1.6e-11 43.4 0.4 2.3 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) GATase_2 PF00310.16 KKK16346.1 - 4.4e-21 75.0 0.0 2.3e-15 56.1 0.0 2.3 1 1 1 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 KKK16346.1 - 1.3e-15 57.4 0.0 2.5e-15 56.5 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 KKK16346.1 - 7.3e-14 51.5 0.0 3.2e-13 49.4 0.0 2.1 2 0 0 2 2 2 1 Glutamine amidotransferase domain Pribosyltran PF00156.22 KKK16346.1 - 6.3e-12 45.3 0.0 1.7e-11 43.8 0.0 1.7 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.1 KKK16346.1 - 2.6e-06 26.3 0.0 4.3e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II PRTase_2 PF15609.1 KKK16346.1 - 0.071 12.4 0.0 0.19 11.0 0.0 1.6 1 1 0 1 1 1 0 Phosphoribosyl transferase Cation_ATPase_N PF00690.21 KKK16347.1 - 7.7e-20 70.1 0.1 1.3e-19 69.4 0.0 1.4 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus E1-E2_ATPase PF00122.15 KKK16347.1 - 4.4e-17 61.9 0.1 4.4e-17 61.9 0.1 1.8 2 0 0 2 2 2 1 E1-E2 ATPase DctM PF06808.7 KKK16347.1 - 9.2e-05 21.1 0.3 0.00011 20.9 0.2 1.1 1 0 0 1 1 1 1 DctM-like transporters Glyco_hydro_28 PF00295.12 KKK16348.1 - 3.6e-51 174.0 7.5 4.7e-51 173.6 5.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 MmgE_PrpD PF03972.9 KKK16349.1 - 2.7e-150 500.4 0.0 3.1e-150 500.2 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family Ubiquitin_2 PF14560.1 KKK16349.1 - 0.03 14.5 0.3 0.072 13.3 0.2 1.6 1 0 0 1 1 1 0 Ubiquitin-like domain DUF4319 PF14203.1 KKK16349.1 - 0.12 11.9 0.1 0.3 10.6 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4319) DNA_methylase PF00145.12 KKK16350.1 - 2.7e-44 151.6 0.0 1.3e-31 109.9 0.0 2.2 1 1 1 2 2 2 2 C-5 cytosine-specific DNA methylase Med9 PF07544.8 KKK16372.1 - 5.2e-25 86.9 0.0 7.9e-25 86.4 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 DivIC PF04977.10 KKK16372.1 - 0.11 11.9 0.1 0.32 10.5 0.0 1.7 1 1 1 2 2 2 0 Septum formation initiator Med21 PF11221.3 KKK16372.1 - 0.65 9.9 4.7 1.1 9.2 3.3 1.7 1 1 0 1 1 1 0 Subunit 21 of Mediator complex Metalloenzyme PF01676.13 KKK16373.1 - 1.2e-71 241.0 0.1 1.4e-71 240.8 0.0 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily iPGM_N PF06415.8 KKK16373.1 - 2.5e-70 236.3 0.0 3.3e-70 235.9 0.0 1.2 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Phosphodiest PF01663.17 KKK16373.1 - 2.4e-06 27.1 0.0 5.4e-06 25.9 0.0 1.6 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 KKK16373.1 - 0.0019 17.4 0.0 0.013 14.6 0.0 2.3 2 1 1 3 3 3 1 Sulfatase AP_endonuc_2 PF01261.19 KKK16373.1 - 0.022 14.0 0.0 0.048 12.9 0.0 1.6 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel Alk_phosphatase PF00245.15 KKK16373.1 - 0.023 13.3 0.1 0.16 10.6 0.0 1.9 2 0 0 2 2 2 0 Alkaline phosphatase Glyco_hydro_92 PF07971.7 KKK16374.1 - 5.3e-21 74.8 0.0 6.1e-21 74.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Prenylcys_lyase PF07156.9 KKK16375.1 - 5.7e-39 134.0 0.0 2.8e-28 98.8 0.0 2.4 1 1 0 2 2 2 2 Prenylcysteine lyase NAD_binding_8 PF13450.1 KKK16375.1 - 2.6e-12 46.5 0.0 6.3e-12 45.3 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 KKK16375.1 - 8.2e-08 31.7 0.0 5.8e-07 28.9 0.0 2.0 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.1 KKK16375.1 - 4.2e-06 26.6 0.1 7.7e-05 22.5 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.19 KKK16375.1 - 1.8e-05 23.8 0.4 7.1e-05 21.8 0.3 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KKK16375.1 - 0.0023 18.2 0.1 2.8 8.4 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KKK16375.1 - 0.0028 17.7 0.0 0.041 13.9 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KKK16375.1 - 0.003 17.4 0.3 0.18 11.6 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KKK16375.1 - 0.0046 15.4 0.3 0.93 7.8 0.2 2.1 2 0 0 2 2 2 2 HI0933-like protein Thi4 PF01946.12 KKK16375.1 - 0.044 12.8 0.1 0.078 12.0 0.1 1.3 1 0 0 1 1 1 0 Thi4 family K_oxygenase PF13434.1 KKK16375.1 - 0.052 12.4 0.0 7.5 5.3 0.0 2.1 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) FAD_oxidored PF12831.2 KKK16375.1 - 0.11 11.5 0.1 1.6 7.6 0.0 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KKK16375.1 - 0.16 10.8 0.6 0.77 8.5 0.3 1.9 2 0 0 2 2 2 0 FAD binding domain SHMT PF00464.14 KKK16376.1 - 1.4e-207 688.8 0.0 1.6e-207 688.6 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.16 KKK16376.1 - 9.4e-06 24.8 0.0 2.7e-05 23.2 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 KKK16376.1 - 0.00013 20.7 0.0 0.0002 20.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 KKK16376.1 - 0.018 14.1 0.0 0.032 13.3 0.0 1.4 1 1 0 1 1 1 0 Beta-eliminating lyase PCI_Csn8 PF10075.4 KKK16377.1 - 1.8e-42 144.5 0.1 2.3e-42 144.1 0.0 1.1 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 KKK16377.1 - 7.8e-17 61.4 0.3 1.6e-14 53.9 0.0 2.1 1 1 1 2 2 2 2 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PDCD2_C PF04194.8 KKK16378.1 - 6.2e-53 178.7 0.0 1.3e-52 177.7 0.0 1.5 1 0 0 1 1 1 1 Programmed cell death protein 2, C-terminal putative domain Pkinase PF00069.20 KKK16379.1 - 1.6e-69 234.0 0.0 1.9e-69 233.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK16379.1 - 4.9e-30 104.4 0.0 6.2e-30 104.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KKK16379.1 - 7.7e-07 28.3 0.0 1.4e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KKK16379.1 - 0.00023 20.9 0.1 0.00039 20.2 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 KKK16379.1 - 0.00024 20.2 0.0 0.00043 19.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 KKK16379.1 - 0.0095 15.2 0.0 0.028 13.7 0.0 1.8 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL AMMECR1 PF01871.12 KKK16380.1 - 4.7e-40 136.5 0.0 8.9e-40 135.6 0.0 1.4 1 0 0 1 1 1 1 AMMECR1 DUF3767 PF12597.3 KKK16381.1 - 2.3e-39 133.7 0.8 3.4e-39 133.1 0.3 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3767) PP1c_bdg PF10488.4 KKK16381.1 - 0.059 12.5 0.8 0.1 11.7 0.6 1.4 1 0 0 1 1 1 0 Phosphatase-1 catalytic subunit binding region DUF1744 PF08490.7 KKK16382.1 - 2.1e-153 510.6 0.0 2.9e-153 510.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.14 KKK16382.1 - 1.8e-71 240.6 0.6 1.4e-70 237.7 0.3 2.3 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.16 KKK16382.1 - 2.2e-23 82.7 0.1 5.3e-23 81.5 0.1 1.5 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo2 PF10108.4 KKK16382.1 - 1.7e-09 37.5 0.0 4.2e-09 36.2 0.0 1.6 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.1 KKK16382.1 - 2.2e-05 24.3 0.1 8.8e-05 22.3 0.0 2.1 2 0 0 2 2 2 1 RNase_H superfamily AAA PF00004.24 KKK16383.1 - 7.1e-42 142.7 0.0 1.4e-41 141.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 KKK16383.1 - 7.6e-29 99.3 0.0 4.2e-28 97.0 0.0 2.3 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain MIT PF04212.13 KKK16383.1 - 1.3e-23 82.6 1.8 1.3e-23 82.6 1.2 2.3 3 0 0 3 3 2 1 MIT (microtubule interacting and transport) domain AAA_17 PF13207.1 KKK16383.1 - 2.5e-06 28.3 0.4 1.1e-05 26.2 0.0 2.6 2 2 0 2 2 1 1 AAA domain RuvB_N PF05496.7 KKK16383.1 - 7.1e-06 25.2 0.0 1.4e-05 24.3 0.0 1.5 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 KKK16383.1 - 7.4e-06 25.4 0.0 1.6e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_22 PF13401.1 KKK16383.1 - 1e-05 25.6 0.1 0.00083 19.5 0.1 2.6 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KKK16383.1 - 1.4e-05 24.8 0.0 9e-05 22.2 0.0 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) DUF815 PF05673.8 KKK16383.1 - 3.9e-05 22.7 0.0 0.00062 18.7 0.0 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF815) RNA_helicase PF00910.17 KKK16383.1 - 3.9e-05 23.7 0.0 0.0085 16.2 0.0 2.8 2 0 0 2 2 2 1 RNA helicase AAA_25 PF13481.1 KKK16383.1 - 5.2e-05 22.7 0.1 0.12 11.7 0.1 3.2 2 1 1 3 3 3 2 AAA domain AAA_16 PF13191.1 KKK16383.1 - 7.2e-05 22.8 0.0 0.00092 19.2 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain TIP49 PF06068.8 KKK16383.1 - 8.2e-05 21.4 0.0 0.00013 20.8 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.1 KKK16383.1 - 0.00023 21.0 0.0 0.00059 19.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KKK16383.1 - 0.00032 20.6 0.0 0.00065 19.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.9 KKK16383.1 - 0.00095 19.1 0.0 0.0071 16.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_18 PF13238.1 KKK16383.1 - 0.0023 18.2 0.1 0.011 16.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain Bac_DnaA PF00308.13 KKK16383.1 - 0.0053 16.4 0.0 0.03 13.9 0.0 2.0 1 1 0 1 1 1 1 Bacterial dnaA protein USP8_dimer PF08969.6 KKK16383.1 - 0.0068 16.3 2.4 0.016 15.1 1.6 1.7 1 0 0 1 1 1 1 USP8 dimerisation domain AAA_19 PF13245.1 KKK16383.1 - 0.0077 15.9 0.0 0.023 14.4 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain Arch_ATPase PF01637.13 KKK16383.1 - 0.0085 15.8 0.1 0.25 10.9 0.0 2.6 2 1 1 3 3 3 1 Archaeal ATPase Zeta_toxin PF06414.7 KKK16383.1 - 0.014 14.4 0.1 0.099 11.7 0.0 2.2 1 1 1 2 2 2 0 Zeta toxin Mg_chelatase PF01078.16 KKK16383.1 - 0.019 14.1 0.0 0.074 12.2 0.0 2.0 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI NACHT PF05729.7 KKK16383.1 - 0.025 14.2 0.0 0.59 9.7 0.0 2.2 1 1 1 2 2 2 0 NACHT domain AAA_24 PF13479.1 KKK16383.1 - 0.032 13.8 0.1 0.098 12.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain CPT PF07931.7 KKK16383.1 - 0.051 13.1 0.0 0.24 11.0 0.0 1.9 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein Guanylate_kin PF00625.16 KKK16383.1 - 0.057 12.8 0.0 0.18 11.2 0.0 1.9 1 0 0 1 1 1 0 Guanylate kinase ResIII PF04851.10 KKK16383.1 - 0.093 12.5 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Parvo_NS1 PF01057.12 KKK16383.1 - 0.097 11.5 0.0 0.21 10.4 0.0 1.5 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_28 PF13521.1 KKK16383.1 - 0.12 12.3 0.0 0.24 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain Prefoldin_2 PF01920.15 KKK16384.1 - 7.1e-19 67.5 13.0 7.7e-19 67.4 6.9 1.9 2 0 0 2 2 2 1 Prefoldin subunit Atg14 PF10186.4 KKK16384.1 - 0.03 13.2 5.5 0.039 12.8 3.8 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Prefoldin_3 PF13758.1 KKK16384.1 - 0.056 13.2 4.5 0.14 11.9 3.1 1.9 1 1 0 1 1 1 0 Prefoldin subunit IncA PF04156.9 KKK16384.1 - 0.084 12.4 15.8 0.51 9.8 7.8 2.1 1 1 1 2 2 2 0 IncA protein ERp29 PF07749.7 KKK16384.1 - 0.19 12.3 2.8 0.43 11.2 1.9 1.6 1 1 0 1 1 1 0 Endoplasmic reticulum protein ERp29, C-terminal domain DivIC PF04977.10 KKK16384.1 - 0.24 10.9 15.1 0.12 11.8 0.8 3.1 3 0 0 3 3 3 0 Septum formation initiator DUF1319 PF07028.6 KKK16384.1 - 1 9.5 7.5 1.3 9.2 3.0 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF1319) COG2 PF06148.6 KKK16384.1 - 1.9 8.3 6.8 1.4 8.7 0.9 2.2 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Prefoldin PF02996.12 KKK16384.1 - 2.3 7.8 11.8 0.11 12.0 2.1 2.7 2 1 1 3 3 3 0 Prefoldin subunit Spc7 PF08317.6 KKK16384.1 - 2.6 6.6 11.1 2.4 6.7 6.7 1.6 1 1 1 2 2 2 0 Spc7 kinetochore protein Sugarporin_N PF11471.3 KKK16384.1 - 2.8 7.6 9.7 0.53 9.9 0.1 3.0 3 0 0 3 3 3 0 Maltoporin periplasmic N-terminal extension Tropomyosin_1 PF12718.2 KKK16384.1 - 3.5 7.4 11.6 1.7 8.5 2.0 2.7 3 0 0 3 3 3 0 Tropomyosin like DUF3571 PF12095.3 KKK16384.1 - 3.9 7.7 5.6 3.3 8.0 0.2 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF3571) Spc24 PF08286.6 KKK16384.1 - 9.5 5.9 13.3 1.2 8.8 1.6 2.6 1 1 2 3 3 3 0 Spc24 subunit of Ndc80 SGT1 PF07093.6 KKK16385.1 - 6.8e-138 460.6 23.2 3e-125 418.9 2.6 3.0 1 1 1 2 2 2 2 SGT1 protein eIF-1a PF01176.14 KKK16385.1 - 0.029 13.7 0.1 0.81 9.1 0.1 2.7 3 0 0 3 3 3 0 Translation initiation factor 1A / IF-1 Siva PF05458.7 KKK16385.1 - 0.16 11.5 0.0 0.28 10.7 0.0 1.3 1 0 0 1 1 1 0 Cd27 binding protein (Siva) Microtub_assoc PF07989.6 KKK16386.1 - 4.2e-27 93.7 5.6 4.2e-27 93.7 3.9 10.6 9 4 6 15 15 15 1 Microtubule associated PACT_coil_coil PF10495.4 KKK16386.1 - 6.3e-27 93.3 1.0 2e-26 91.7 0.7 2.0 1 0 0 1 1 1 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein Bacillus_HBL PF05791.6 KKK16386.1 - 0.00012 21.5 10.1 0.00012 21.5 7.0 7.3 3 2 2 6 6 6 1 Bacillus haemolytic enterotoxin (HBL) TMF_DNA_bd PF12329.3 KKK16386.1 - 0.00059 19.5 13.3 0.00059 19.5 9.2 14.3 8 4 4 14 14 14 3 TATA element modulatory factor 1 DNA binding Tropomyosin_1 PF12718.2 KKK16386.1 - 0.0041 16.9 14.5 0.0041 16.9 10.1 11.5 2 2 11 13 13 13 1 Tropomyosin like Nop PF01798.13 KKK16387.1 - 3.5e-60 201.6 0.1 3.5e-60 201.6 0.0 1.9 2 0 0 2 2 2 1 Putative snoRNA binding domain NOSIC PF08060.8 KKK16387.1 - 3.9e-25 87.3 0.4 8.5e-25 86.3 0.3 1.6 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 KKK16387.1 - 8.2e-22 77.1 0.1 8.2e-22 77.1 0.0 2.6 2 0 0 2 2 2 1 NOP5NT (NUC127) domain Abi_2 PF07751.6 KKK16387.1 - 6.7 6.8 8.1 46 4.1 4.7 2.3 2 0 0 2 2 2 0 Abi-like protein G0-G1_switch_2 PF15103.1 KKK16387.1 - 8.9 6.6 8.0 70 3.7 0.0 2.6 2 0 0 2 2 2 0 G0/G1 switch protein 2 DUF2457 PF10446.4 KKK16388.1 - 0.0013 17.5 5.3 0.0015 17.3 3.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) Cpn60_TCP1 PF00118.19 KKK16389.1 - 1.2e-150 502.3 0.1 1.4e-150 502.1 0.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family MOZ_SAS PF01853.13 KKK16390.1 - 1.3e-55 187.6 0.0 1.7e-53 180.7 0.0 2.1 1 1 0 1 1 1 1 MOZ/SAS family RRM_1 PF00076.17 KKK16391.1 - 7e-12 44.8 0.0 1.2e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KKK16391.1 - 3.7e-09 36.4 0.0 6.7e-09 35.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) tRNA-synt_2 PF00152.15 KKK16392.1 - 5.4e-57 193.0 0.0 8.5e-57 192.4 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 KKK16392.1 - 4.7e-06 26.3 0.0 8e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA_anti-like PF12869.2 KKK16392.1 - 0.03 13.7 0.0 0.049 13.1 0.0 1.2 1 0 0 1 1 1 0 tRNA_anti-like FAM53 PF15242.1 KKK16392.1 - 0.15 11.5 2.1 0.15 11.5 0.3 1.8 2 0 0 2 2 2 0 Family of FAM53 ILVD_EDD PF00920.16 KKK16394.1 - 2.1e-201 669.9 0.8 2.4e-201 669.6 0.6 1.0 1 0 0 1 1 1 1 Dehydratase family FTCD_C PF04961.7 KKK16394.1 - 0.089 12.1 0.4 0.17 11.2 0.2 1.4 1 0 0 1 1 1 0 Formiminotransferase-cyclodeaminase Abhydrolase_6 PF12697.2 KKK16395.1 - 9.6e-23 81.2 0.0 1.6e-22 80.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KKK16395.1 - 1.4e-20 73.8 0.0 8.4e-13 48.4 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KKK16395.1 - 2.1e-07 30.7 0.0 1.3e-06 28.2 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.9 KKK16395.1 - 0.00081 17.9 0.0 0.0011 17.4 0.0 1.1 1 0 0 1 1 1 1 Ndr family Abhydrolase_4 PF08386.5 KKK16395.1 - 0.0091 15.8 0.0 0.021 14.6 0.0 1.6 1 0 0 1 1 1 1 TAP-like protein DUF3246 PF11596.3 KKK16395.1 - 0.023 14.0 4.6 0.035 13.3 3.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) DUF4611 PF15387.1 KKK16395.1 - 0.026 14.6 4.5 0.03 14.4 2.4 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) SR-25 PF10500.4 KKK16395.1 - 0.1 12.0 8.9 0.17 11.3 6.2 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Sigma70_ner PF04546.8 KKK16395.1 - 0.29 10.7 2.2 0.44 10.1 1.5 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF4207 PF13904.1 KKK16395.1 - 6.2 6.1 9.0 9.4 5.5 6.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4207) DUF1900 PF08954.6 KKK16396.1 - 3.4e-48 162.6 0.0 1.9e-47 160.1 0.0 2.1 2 1 0 3 3 3 1 Domain of unknown function (DUF1900) DUF1899 PF08953.6 KKK16396.1 - 4.5e-35 119.0 0.0 8.4e-35 118.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40 PF00400.27 KKK16396.1 - 1.5e-24 84.8 0.7 2.8e-07 30.1 0.0 4.0 3 0 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.3 KKK16396.1 - 0.00093 17.4 0.2 0.2 9.7 0.1 2.2 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Kinesin PF00225.18 KKK16397.1 - 4.5e-105 351.0 0.3 4.5e-105 351.0 0.2 2.1 2 1 0 2 2 2 1 Kinesin motor domain WEMBL PF05701.6 KKK16397.1 - 0.091 11.2 44.7 0.12 10.8 26.5 2.8 2 1 1 3 3 3 0 Weak chloroplast movement under blue light T2SF PF00482.18 KKK16397.1 - 5.8 6.8 7.2 1.5 8.7 0.1 3.0 2 1 0 2 2 2 0 Type II secretion system (T2SS), protein F MFS_1 PF07690.11 KKK16399.1 - 2.9e-17 62.4 54.7 1.1e-15 57.2 19.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily RAI16-like PF10257.4 KKK16400.1 - 3.7e-87 292.5 0.0 5.4e-87 292.0 0.0 1.2 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein CBFD_NFYB_HMF PF00808.18 KKK16401.1 - 9.1e-16 57.6 2.3 1.5e-15 56.9 1.6 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 KKK16401.1 - 2.2e-07 30.9 0.6 3.3e-07 30.3 0.4 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 DUF1115 PF06544.7 KKK16404.1 - 2.3e-19 69.3 0.0 3.8e-19 68.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) Pribosyltran_N PF13793.1 KKK16405.1 - 5.1e-44 148.7 0.0 6e-41 138.8 0.0 2.4 2 0 0 2 2 2 2 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 KKK16405.1 - 1.4e-35 122.6 0.1 1.1e-30 106.7 0.0 2.3 2 0 0 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 KKK16405.1 - 9.3e-06 25.3 0.0 0.00024 20.8 0.1 2.6 2 0 0 2 2 2 1 Phosphoribosyl transferase domain COPI_C PF06957.6 KKK16405.1 - 0.19 10.2 0.1 0.48 8.9 0.0 1.6 2 0 0 2 2 2 0 Coatomer (COPI) alpha subunit C-terminus Ldh_1_N PF00056.18 KKK16407.1 - 7.5e-44 148.9 0.0 6e-43 146.0 0.0 2.0 2 0 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 KKK16407.1 - 1.8e-42 145.0 0.0 2.9e-42 144.3 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.14 KKK16407.1 - 0.0011 17.6 0.0 0.0016 17.1 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 KKK16407.1 - 0.023 14.9 0.3 0.49 10.7 0.0 2.7 2 1 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.14 KKK16407.1 - 0.057 12.4 0.1 0.54 9.3 0.0 2.5 2 1 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain AAA PF00004.24 KKK16408.1 - 1.2e-17 64.2 0.0 2.3e-17 63.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KKK16408.1 - 2.1e-05 24.6 0.1 0.00053 20.1 0.0 2.9 1 1 2 3 3 3 1 AAA domain AAA_17 PF13207.1 KKK16408.1 - 4.8e-05 24.1 1.4 0.0025 18.6 0.0 3.4 2 1 1 3 3 3 1 AAA domain AAA_16 PF13191.1 KKK16408.1 - 0.00026 21.0 0.0 0.0011 19.0 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_19 PF13245.1 KKK16408.1 - 0.003 17.2 0.0 0.011 15.4 0.0 2.0 1 0 0 1 1 1 1 Part of AAA domain AAA_5 PF07728.9 KKK16408.1 - 0.0062 16.2 0.0 0.012 15.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 KKK16408.1 - 0.019 14.4 0.0 0.037 13.4 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_14 PF13173.1 KKK16408.1 - 0.027 14.3 0.0 0.06 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 KKK16408.1 - 0.047 13.5 0.0 0.13 12.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.1 KKK16408.1 - 0.064 12.8 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain Zot PF05707.7 KKK16408.1 - 0.098 12.1 0.1 0.95 8.8 0.1 2.1 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) Rad17 PF03215.10 KKK16408.1 - 0.11 11.1 0.0 0.18 10.4 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_30 PF13604.1 KKK16408.1 - 0.13 11.8 0.0 0.26 10.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF566 PF04484.7 KKK16408.1 - 2.9 7.3 5.0 6.5 6.1 3.4 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF566) V-SNARE_C PF12352.3 KKK16409.1 - 5.5e-16 58.3 0.6 1.3e-15 57.2 0.3 1.8 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 KKK16409.1 - 0.0002 20.9 0.0 0.0015 18.2 0.0 2.3 2 0 0 2 2 2 1 Sec20 GRA6 PF05084.8 KKK16409.1 - 0.0035 16.8 1.3 0.0086 15.6 0.9 1.6 1 0 0 1 1 1 1 Granule antigen protein (GRA6) BAR_2 PF10455.4 KKK16409.1 - 0.0093 14.9 0.0 0.0093 14.9 0.0 1.6 2 0 0 2 2 2 1 Bin/amphiphysin/Rvs domain for vesicular trafficking She9_MDM33 PF05546.6 KKK16409.1 - 0.021 14.3 0.2 0.021 14.3 0.1 1.9 2 0 0 2 2 2 0 She9 / Mdm33 family Sigma70_r4 PF04545.11 KKK16409.1 - 0.035 13.4 0.3 0.079 12.2 0.2 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 TPR_MLP1_2 PF07926.7 KKK16409.1 - 0.85 9.3 9.2 0.26 11.0 1.1 2.7 3 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein CPSF100_C PF13299.1 KKK16409.1 - 0.89 9.7 5.7 0.27 11.4 0.6 2.1 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal PP28 PF10252.4 KKK16409.1 - 2.6 8.1 11.2 0.06 13.3 1.1 2.6 2 1 0 2 2 2 0 Casein kinase substrate phosphoprotein PP28 2-oxoacid_dh PF00198.18 KKK16410.1 - 2.4e-78 262.5 0.1 3.2e-78 262.1 0.0 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 KKK16410.1 - 5.8e-17 61.1 2.3 1.4e-16 59.8 0.3 2.4 2 0 0 2 2 2 1 Biotin-requiring enzyme E3_binding PF02817.12 KKK16410.1 - 2e-13 49.7 0.7 4.8e-13 48.5 0.5 1.7 1 0 0 1 1 1 1 e3 binding domain Sec7 PF01369.15 KKK16411.1 - 2.5e-64 216.4 0.8 7.4e-64 214.9 0.5 1.9 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 KKK16411.1 - 1.5e-55 187.1 9.0 1.5e-55 187.1 6.3 3.3 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 KKK16411.1 - 1e-32 111.4 3.0 6e-31 105.8 0.1 3.9 3 0 0 3 3 3 2 Domain of unknown function (DUF1981) NAD_binding_7 PF13241.1 KKK16412.1 - 1.2e-32 112.1 0.0 1.9e-32 111.6 0.0 1.3 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.1 KKK16412.1 - 7.7e-30 102.0 0.0 1.2e-29 101.3 0.0 1.3 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.1 KKK16412.1 - 1.9e-15 55.5 0.1 3.2e-15 54.7 0.1 1.4 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central TrkA_N PF02254.13 KKK16412.1 - 0.019 14.9 0.1 0.042 13.8 0.1 1.6 1 1 0 1 1 1 0 TrkA-N domain Shikimate_DH PF01488.15 KKK16412.1 - 0.06 13.4 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase APH PF01636.18 KKK16417.1 - 2.8e-12 46.9 0.2 3.1e-11 43.4 0.2 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 KKK16417.1 - 0.15 11.1 0.0 0.24 10.4 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase PA14_2 PF10528.4 KKK16418.1 - 2.5e-06 27.4 0.4 8.4e-06 25.7 0.3 2.0 1 0 0 1 1 1 1 GLEYA domain Nse4-Nse3_bdg PF15412.1 KKK16420.1 - 0.003 17.3 0.0 0.0064 16.3 0.0 1.5 1 0 0 1 1 1 1 Binding domain of Nse4/EID3 to Nse3-MAGE Borrelia_REV PF03978.8 KKK16420.1 - 0.042 13.5 0.9 0.046 13.4 0.6 1.2 1 0 0 1 1 1 0 Borrelia burgdorferi REV protein Sugar_tr PF00083.19 KKK16421.1 - 2.4e-123 412.0 19.3 2.8e-123 411.8 13.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KKK16421.1 - 1.9e-21 76.1 24.1 1.9e-21 76.1 16.7 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily TPR_14 PF13428.1 KKK16421.1 - 0.092 13.4 0.1 0.22 12.2 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat UNC-93 PF05978.11 KKK16423.1 - 7e-11 41.8 6.6 7e-11 41.8 4.6 3.4 4 0 0 4 4 4 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.11 KKK16423.1 - 1e-10 40.9 36.0 1e-10 40.9 25.0 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Amidohydro_1 PF01979.15 KKK16424.1 - 1.4e-13 51.2 0.0 2.8e-13 50.2 0.0 1.5 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 KKK16424.1 - 7.1e-11 42.6 4.1 7.3e-10 39.3 2.9 2.1 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 KKK16424.1 - 1.2e-05 25.0 0.0 6.2e-05 22.7 0.0 2.2 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_3 PF07969.6 KKK16424.1 - 6.2e-05 22.3 0.1 0.00015 21.1 0.0 1.7 1 0 0 1 1 1 1 Amidohydrolase family MFS_1 PF07690.11 KKK16425.1 - 1.1e-30 106.5 32.5 6.9e-28 97.3 13.7 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KKK16425.1 - 2.7e-12 45.9 3.6 2.7e-12 45.9 2.5 1.8 2 0 0 2 2 2 1 Sugar (and other) transporter Kinetocho_Slk19 PF12709.2 KKK16426.1 - 1.4e-24 85.9 29.3 1.9e-23 82.3 5.8 4.3 4 0 0 4 4 4 2 Central kinetochore-associated Fib_alpha PF08702.5 KKK16426.1 - 2.4 8.2 14.2 39 4.3 0.0 3.3 2 2 1 3 3 3 0 Fibrinogen alpha/beta chain family ERM PF00769.14 KKK16426.1 - 5.8 6.3 50.3 1.6 8.1 17.4 3.1 2 1 0 3 3 3 0 Ezrin/radixin/moesin family Fungal_trans PF04082.13 KKK16428.1 - 1.1e-36 126.1 2.0 1.6e-36 125.5 1.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK16428.1 - 0.0015 18.4 18.5 0.003 17.4 12.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_jaz PF12171.3 KKK16429.1 - 0.00093 19.2 3.1 0.19 11.9 0.3 3.3 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 KKK16429.1 - 0.0013 18.8 39.9 0.077 13.3 1.0 7.0 6 0 0 6 6 6 4 C2H2-type zinc finger DUF3446 PF11928.3 KKK16430.1 - 0.043 13.9 5.0 0.054 13.6 3.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3446) DbpA PF03880.10 KKK16431.1 - 0.0055 16.3 0.0 0.011 15.3 0.0 1.6 1 0 0 1 1 1 1 DbpA RNA binding domain Peptidase_S10 PF00450.17 KKK16433.1 - 2.9e-110 369.3 0.4 3.4e-110 369.0 0.3 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Sec66 PF09802.4 KKK16434.1 - 3.5e-83 277.6 1.0 4.2e-83 277.4 0.7 1.1 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 Sec2p PF06428.6 KKK16434.1 - 0.0056 16.4 2.7 0.0056 16.4 1.9 1.8 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p NIT PF08376.5 KKK16434.1 - 0.039 13.4 4.0 0.059 12.8 2.8 1.3 1 0 0 1 1 1 0 Nitrate and nitrite sensing Lamp PF01299.12 KKK16434.1 - 0.18 10.9 1.2 0.23 10.5 0.8 1.3 1 0 0 1 1 1 0 Lysosome-associated membrane glycoprotein (Lamp) AAA PF00004.24 KKK16435.1 - 8.1e-48 161.9 0.0 1.9e-42 144.5 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 KKK16435.1 - 3.8e-07 29.6 0.0 4.5e-06 26.1 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_16 PF13191.1 KKK16435.1 - 3.4e-06 27.1 0.0 3.6e-05 23.8 0.0 2.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_2 PF07724.9 KKK16435.1 - 4.9e-06 26.5 0.0 1.1e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 KKK16435.1 - 2.2e-05 24.6 0.1 0.00092 19.3 0.0 3.3 2 1 0 2 2 1 1 AAA domain Sigma54_activ_2 PF14532.1 KKK16435.1 - 5.7e-05 23.1 0.0 0.067 13.2 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_5 PF07728.9 KKK16435.1 - 0.00018 21.2 0.1 0.00087 19.0 0.0 2.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Bromodomain PF00439.20 KKK16435.1 - 0.00054 19.8 0.0 0.0018 18.1 0.0 1.8 1 0 0 1 1 1 1 Bromodomain AAA_14 PF13173.1 KKK16435.1 - 0.0016 18.3 0.0 0.005 16.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KKK16435.1 - 0.0024 18.6 1.3 0.011 16.5 0.0 2.8 3 0 0 3 3 1 1 AAA domain AAA_25 PF13481.1 KKK16435.1 - 0.0029 17.0 0.0 0.0099 15.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 KKK16435.1 - 0.0036 17.4 0.0 0.0089 16.1 0.0 1.7 1 0 0 1 1 1 1 RNA helicase AAA_19 PF13245.1 KKK16435.1 - 0.005 16.5 0.0 0.023 14.4 0.0 2.1 1 0 0 1 1 1 1 Part of AAA domain AAA_33 PF13671.1 KKK16435.1 - 0.0071 16.2 0.0 0.019 14.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 KKK16435.1 - 0.012 14.3 0.0 0.02 13.6 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus AAA_18 PF13238.1 KKK16435.1 - 0.013 15.7 0.0 0.057 13.7 0.0 2.2 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 KKK16435.1 - 0.024 14.2 0.0 0.054 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.7 KKK16435.1 - 0.032 13.2 0.0 0.064 12.2 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_28 PF13521.1 KKK16435.1 - 0.032 14.2 0.0 0.071 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 KKK16435.1 - 0.037 13.1 0.0 0.095 11.8 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ABC_tran PF00005.22 KKK16435.1 - 0.043 14.1 0.0 0.17 12.1 0.0 2.0 2 0 0 2 2 1 0 ABC transporter Sigma54_activat PF00158.21 KKK16435.1 - 0.048 13.1 0.0 1.2 8.5 0.0 2.7 2 1 0 2 2 2 0 Sigma-54 interaction domain NACHT PF05729.7 KKK16435.1 - 0.056 13.1 0.0 0.18 11.4 0.0 1.9 1 1 0 1 1 1 0 NACHT domain DUF2075 PF09848.4 KKK16435.1 - 0.075 11.9 0.0 0.14 11.0 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) MobB PF03205.9 KKK16435.1 - 0.085 12.5 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Parvo_NS1 PF01057.12 KKK16435.1 - 0.091 11.6 0.0 0.19 10.5 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_3 PF07726.6 KKK16435.1 - 0.1 12.1 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.11 KKK16435.1 - 0.1 11.7 0.0 0.25 10.5 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein Torsin PF06309.6 KKK16435.1 - 0.17 11.7 0.0 0.51 10.2 0.0 1.7 1 0 0 1 1 1 0 Torsin PIF1 PF05970.9 KKK16435.1 - 0.52 9.2 0.0 0.85 8.4 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase DUF4187 PF13821.1 KKK16436.1 - 3e-19 68.3 3.1 3e-19 68.3 2.2 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4187) G-patch PF01585.18 KKK16436.1 - 1.5e-08 34.2 0.3 2.3e-06 27.2 0.1 2.5 2 0 0 2 2 2 2 G-patch domain COesterase PF00135.23 KKK16437.1 - 2.2e-90 303.8 0.5 1.6e-83 281.2 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 KKK16437.1 - 2.2e-07 30.6 0.3 1.2e-06 28.3 0.2 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KKK16437.1 - 6.8e-07 28.7 0.1 1e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KKK16437.1 - 0.00051 19.8 0.1 0.00051 19.8 0.1 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Nop14 PF04147.7 KKK16438.1 - 2.2e-286 952.2 30.2 2.5e-286 952.0 20.9 1.0 1 0 0 1 1 1 1 Nop14-like family HEAT_2 PF13646.1 KKK16439.1 - 0.036 14.3 0.2 0.08 13.2 0.1 1.6 1 0 0 1 1 1 0 HEAT repeats HEAT PF02985.17 KKK16439.1 - 0.039 14.0 0.1 0.65 10.2 0.0 2.7 2 0 0 2 2 2 0 HEAT repeat CDC45 PF02724.9 KKK16439.1 - 0.074 11.0 0.3 0.096 10.7 0.2 1.2 1 0 0 1 1 1 0 CDC45-like protein Peptidase_S49_N PF08496.5 KKK16440.1 - 2.6 7.8 7.6 6.5 6.5 3.2 2.2 2 0 0 2 2 2 0 Peptidase family S49 N-terminal IncA PF04156.9 KKK16441.1 - 0.013 15.0 4.5 0.017 14.6 3.1 1.2 1 0 0 1 1 1 0 IncA protein ORC3_N PF07034.6 KKK16442.1 - 4.7e-32 111.2 0.0 1.7e-30 106.1 0.0 2.3 1 1 0 1 1 1 1 Origin recognition complex (ORC) subunit 3 N-terminus PPR_2 PF13041.1 KKK16443.1 - 1e-07 31.7 0.2 0.097 12.6 0.0 4.9 5 1 1 6 6 6 2 PPR repeat family PPR_3 PF13812.1 KKK16443.1 - 9.5e-05 22.3 0.0 17 6.0 0.0 6.2 7 0 0 7 7 7 2 Pentatricopeptide repeat domain PPR PF01535.15 KKK16443.1 - 0.024 14.5 2.0 7.5 6.7 0.0 4.6 5 0 0 5 5 5 0 PPR repeat DUF869 PF05911.6 KKK16444.1 - 0.92 7.6 57.3 0.023 12.9 5.4 2.1 1 1 1 2 2 2 0 Plant protein of unknown function (DUF869) Filament PF00038.16 KKK16444.1 - 1 8.7 64.8 1.2 8.4 42.3 2.6 1 1 1 2 2 2 0 Intermediate filament protein zf-C2H2 PF00096.21 KKK16445.1 - 2.7e-05 24.2 22.7 0.15 12.5 0.2 4.6 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KKK16445.1 - 0.84 10.1 23.9 3.6 8.1 0.3 4.7 4 0 0 4 4 4 0 C2H2-type zinc finger DUF2890 PF11081.3 KKK16445.1 - 2 8.4 10.7 0.04 13.9 1.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2890) FBPase PF00316.15 KKK16455.1 - 1e-119 399.1 0.0 1.2e-119 398.9 0.0 1.0 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase Aha1_N PF09229.6 KKK16456.1 - 5.7e-40 136.3 0.4 9.7e-40 135.5 0.3 1.4 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.6 KKK16456.1 - 6.4e-18 65.0 0.8 1.2e-17 64.2 0.2 1.7 2 0 0 2 2 2 1 Activator of Hsp90 ATPase homolog 1-like protein Pox_A12 PF04651.8 KKK16456.1 - 0.012 15.7 0.8 0.02 15.0 0.5 1.3 1 0 0 1 1 1 0 Poxvirus A12 protein DUF2454 PF10521.4 KKK16456.1 - 0.069 12.1 0.1 0.1 11.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2454) Saccharop_dh PF03435.13 KKK16457.1 - 7.6e-128 426.7 0.0 1.9e-127 425.4 0.0 1.6 2 0 0 2 2 2 1 Saccharopine dehydrogenase Prenyltransf PF01255.14 KKK16457.1 - 1.9e-79 265.9 0.0 3.9e-79 264.8 0.0 1.5 1 1 0 1 1 1 1 Putative undecaprenyl diphosphate synthase Shikimate_DH PF01488.15 KKK16457.1 - 1.3e-09 38.3 0.3 2.7e-09 37.2 0.2 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.1 KKK16457.1 - 4.5e-07 30.0 0.4 4.6e-06 26.7 0.1 2.2 2 0 0 2 2 2 1 NADH(P)-binding NmrA PF05368.8 KKK16457.1 - 0.0014 17.8 0.3 0.0023 17.2 0.2 1.3 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.14 KKK16457.1 - 0.0049 15.6 0.1 0.011 14.5 0.0 1.5 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_7 PF13241.1 KKK16457.1 - 0.045 13.9 0.1 0.16 12.2 0.2 1.9 2 0 0 2 2 2 0 Putative NAD(P)-binding Acyltransferase PF01553.16 KKK16458.1 - 1.5e-10 40.5 0.0 0.00019 20.8 0.0 2.3 2 0 0 2 2 2 2 Acyltransferase WWbp PF10349.4 KKK16459.1 - 6.4e-14 52.8 0.4 1.7e-13 51.4 0.1 1.8 2 0 0 2 2 2 1 WW-domain ligand protein Vps36_ESCRT-II PF11605.3 KKK16459.1 - 2e-05 24.2 0.0 5.6e-05 22.8 0.0 1.7 2 0 0 2 2 2 1 Vacuolar protein sorting protein 36 Vps36 GRAM PF02893.15 KKK16459.1 - 0.13 11.8 0.0 0.28 10.7 0.0 1.6 1 1 0 1 1 1 0 GRAM domain UCR_hinge PF02320.11 KKK16460.1 - 1.7e-25 88.7 7.7 1.7e-25 88.7 5.3 1.9 2 1 0 2 2 1 1 Ubiquinol-cytochrome C reductase hinge protein Trypan_PARP PF05887.6 KKK16460.1 - 0.15 11.8 27.5 0.23 11.2 19.1 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Vfa1 PF08432.5 KKK16460.1 - 0.2 11.6 16.5 0.24 11.3 11.4 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DHHW PF14286.1 KKK16460.1 - 0.22 10.7 8.8 0.29 10.4 6.1 1.3 1 0 0 1 1 1 0 DHHW protein CDC45 PF02724.9 KKK16460.1 - 0.29 9.1 14.6 0.3 9.0 10.1 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4211 PF13926.1 KKK16460.1 - 0.42 10.0 8.9 1.4 8.3 6.1 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4211) Raftlin PF15250.1 KKK16460.1 - 0.66 8.4 8.9 0.7 8.3 6.1 1.2 1 0 0 1 1 1 0 Raftlin Zip PF02535.17 KKK16460.1 - 0.77 8.6 7.2 0.89 8.4 5.0 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter RR_TM4-6 PF06459.7 KKK16460.1 - 0.8 9.5 20.0 0.89 9.3 13.9 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF1510 PF07423.6 KKK16460.1 - 1 8.6 26.0 1.3 8.3 18.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) AUX_IAA PF02309.11 KKK16460.1 - 1.2 8.8 7.0 1.5 8.5 4.9 1.2 1 0 0 1 1 1 0 AUX/IAA family Tim54 PF11711.3 KKK16460.1 - 1.5 7.3 17.4 1.8 7.0 12.1 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Daxx PF03344.10 KKK16460.1 - 1.6 7.1 30.9 1.8 6.9 21.4 1.0 1 0 0 1 1 1 0 Daxx Family DUF2058 PF09831.4 KKK16460.1 - 1.6 8.6 8.1 2 8.2 5.6 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) DDHD PF02862.12 KKK16460.1 - 1.6 8.4 11.2 2 8.1 7.7 1.2 1 0 0 1 1 1 0 DDHD domain DUF4045 PF13254.1 KKK16460.1 - 1.6 7.8 16.4 2 7.6 11.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) SAPS PF04499.10 KKK16460.1 - 1.9 6.9 12.3 2.2 6.8 8.5 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein RRN3 PF05327.6 KKK16460.1 - 2 6.4 10.4 2.3 6.2 7.2 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF913 PF06025.7 KKK16460.1 - 3.4 6.3 8.3 4 6.0 5.7 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) HSP90 PF00183.13 KKK16460.1 - 3.4 5.9 21.5 4.3 5.6 14.9 1.2 1 0 0 1 1 1 0 Hsp90 protein DUF4551 PF15087.1 KKK16460.1 - 3.5 5.8 9.8 3.9 5.7 6.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Herpes_TAF50 PF03326.8 KKK16460.1 - 4 6.2 13.7 4.9 5.9 9.5 1.1 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) Hid1 PF12722.2 KKK16460.1 - 4.3 4.8 9.8 4.5 4.8 6.8 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CT47 PF15623.1 KKK16460.1 - 4.7 6.8 34.9 5.6 6.6 24.2 1.2 1 0 0 1 1 1 0 Cancer/testis gene family 47 Nop14 PF04147.7 KKK16460.1 - 5.4 4.8 26.1 5.9 4.6 18.1 1.0 1 0 0 1 1 1 0 Nop14-like family PLRV_ORF5 PF01690.12 KKK16460.1 - 5.4 6.0 16.2 6.3 5.8 11.2 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein MRVI1 PF05781.7 KKK16460.1 - 5.7 5.2 21.0 7.6 4.7 14.5 1.2 1 0 0 1 1 1 0 MRVI1 protein Neur_chan_memb PF02932.11 KKK16460.1 - 7 6.4 6.7 8.3 6.2 4.6 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF3827 PF12877.2 KKK16460.1 - 7.7 4.4 9.8 8.9 4.2 6.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Ycf1 PF05758.7 KKK16460.1 - 9 3.8 17.5 10 3.6 12.1 1.0 1 0 0 1 1 1 0 Ycf1 MFS_1 PF07690.11 KKK16461.1 - 2.9e-12 45.9 22.2 1.8e-11 43.4 13.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Gti1_Pac2 PF09729.4 KKK16464.1 - 1.1e-51 175.0 0.7 7e-51 172.4 0.5 1.9 1 1 0 1 1 1 1 Gti1/Pac2 family PRP21_like_P PF12230.3 KKK16477.1 - 1.2e-64 217.9 13.3 1.9e-64 217.2 9.2 1.3 1 0 0 1 1 1 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.15 KKK16477.1 - 3.8e-36 122.5 6.0 2.9e-19 68.4 0.1 2.7 3 0 0 3 3 3 2 Surp module PMT PF02366.13 KKK16479.1 - 4.8e-77 258.6 17.0 1.1e-76 257.4 11.8 1.6 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 KKK16479.1 - 4.1e-53 179.7 0.0 6.4e-53 179.1 0.0 1.3 1 0 0 1 1 1 1 MIR domain DUF4231 PF14015.1 KKK16479.1 - 1.1 9.2 5.6 0.59 10.1 1.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) SET PF00856.23 KKK16480.1 - 3.2e-18 66.5 0.5 3.2e-18 66.5 0.3 4.2 3 2 0 3 3 3 1 SET domain zf-DHHC PF01529.15 KKK16481.1 - 4.5e-36 123.8 1.4 1.3e-35 122.3 1.0 1.8 1 1 0 1 1 1 1 DHHC palmitoyltransferase Kei1 PF08552.6 KKK16482.1 - 0.053 13.1 1.6 0.082 12.5 1.1 1.2 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Complex1_LYR_1 PF13232.1 KKK16483.1 - 6.3e-16 58.3 5.4 6.3e-16 58.3 3.7 2.0 2 0 0 2 2 2 1 Complex1_LYR-like Complex1_LYR PF05347.10 KKK16483.1 - 1.3e-14 53.7 4.7 1.3e-14 53.7 3.3 2.2 2 0 0 2 2 2 1 Complex 1 protein (LYR family) TPR_12 PF13424.1 KKK16484.1 - 0.061 13.2 0.1 1.8 8.5 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat hEGF PF12661.2 KKK16485.1 - 0.0037 17.2 1.8 0.0083 16.1 1.3 1.6 1 0 0 1 1 1 1 Human growth factor-like EGF DUF997 PF06196.7 KKK16485.1 - 0.095 12.2 0.1 0.17 11.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF997) DUF2207 PF09972.4 KKK16485.1 - 0.22 10.0 0.0 0.38 9.2 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF2749 PF10907.3 KKK16485.1 - 0.5 10.2 1.9 2 8.3 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2749) WD40 PF00400.27 KKK16486.1 - 1.9e-09 37.0 12.0 1.2e-06 28.1 0.2 4.8 6 0 0 6 6 6 2 WD domain, G-beta repeat Gryzun-like PF12742.2 KKK16486.1 - 0.026 14.3 0.0 0.054 13.3 0.0 1.4 1 0 0 1 1 1 0 Gryzun, putative Golgi trafficking Nucleoporin_N PF08801.6 KKK16486.1 - 0.039 12.7 1.3 0.58 8.8 0.1 2.6 1 1 1 2 2 2 0 Nup133 N terminal like MscS_porin PF12795.2 KKK16486.1 - 0.07 12.4 14.4 0.11 11.8 10.0 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain GAS PF13851.1 KKK16486.1 - 0.17 11.0 7.6 0.25 10.5 5.2 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF3373 PF11853.3 KKK16486.1 - 0.3 9.5 2.4 0.5 8.8 1.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) Spc7 PF08317.6 KKK16486.1 - 0.62 8.6 6.6 0.9 8.1 4.6 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF904 PF06005.7 KKK16486.1 - 0.71 10.1 8.0 4.9 7.5 5.6 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF904) DUF724 PF05266.9 KKK16486.1 - 1 8.9 6.7 0.13 11.8 1.3 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF724) IncA PF04156.9 KKK16486.1 - 1.8 8.1 11.3 2.7 7.5 7.8 1.2 1 0 0 1 1 1 0 IncA protein ADIP PF11559.3 KKK16486.1 - 7.8 6.3 12.9 5.8 6.7 6.6 1.9 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding NIPSNAP PF07978.8 KKK16488.1 - 8e-38 128.5 5.4 8.6e-28 96.3 0.1 2.6 3 0 0 3 3 3 2 NIPSNAP FSH1 PF03959.8 KKK16489.1 - 1e-72 244.0 0.0 1.8e-72 243.2 0.0 1.4 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 KKK16489.1 - 1.2e-10 41.6 3.0 1.8e-10 41.0 2.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KKK16489.1 - 4.1e-06 26.6 3.5 2.2e-05 24.2 2.4 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 KKK16489.1 - 0.00052 19.5 0.5 0.64 9.4 0.5 2.8 3 0 0 3 3 3 2 Phospholipase/Carboxylesterase SR-25 PF10500.4 KKK16489.1 - 7.7 5.9 10.8 12 5.2 7.5 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Ribosomal_S27e PF01667.12 KKK16490.1 - 1.4e-27 94.9 6.8 2.6e-27 94.1 4.7 1.5 1 0 0 1 1 1 1 Ribosomal protein S27 CDP-OH_P_transf PF01066.16 KKK16490.1 - 1.6e-16 60.4 4.9 1.6e-16 60.4 3.4 2.7 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase IBR PF01485.16 KKK16490.1 - 0.13 12.1 1.2 0.24 11.2 0.8 1.4 1 0 0 1 1 1 0 IBR domain TP_methylase PF00590.15 KKK16491.1 - 2.3e-46 158.1 0.1 3.4e-46 157.5 0.0 1.3 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_7 PF13241.1 KKK16491.1 - 2.4e-15 56.6 0.0 4.6e-15 55.7 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.1 KKK16491.1 - 1.9e-11 43.0 0.0 7.2e-08 31.6 0.0 2.4 2 0 0 2 2 2 2 Sirohaem biosynthesis protein C-terminal CW_binding_2 PF04122.7 KKK16491.1 - 0.1 12.8 0.0 0.28 11.3 0.0 1.7 1 0 0 1 1 1 0 Putative cell wall binding repeat 2 DeoC PF01791.4 KKK16492.1 - 6.7e-39 133.5 3.7 7.9e-39 133.3 2.6 1.1 1 0 0 1 1 1 1 DeoC/LacD family aldolase DHO_dh PF01180.16 KKK16492.1 - 0.018 14.0 3.0 0.031 13.2 1.8 1.6 1 1 0 1 1 1 0 Dihydroorotate dehydrogenase His_biosynth PF00977.16 KKK16492.1 - 0.033 13.4 0.2 0.07 12.3 0.2 1.5 1 0 0 1 1 1 0 Histidine biosynthesis protein DUF3375 PF11855.3 KKK16492.1 - 0.047 12.4 0.4 0.058 12.1 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3375) FMN_dh PF01070.13 KKK16492.1 - 0.047 12.5 3.5 0.1 11.4 2.4 1.7 1 1 0 1 1 1 0 FMN-dependent dehydrogenase BPL_LplA_LipB PF03099.14 KKK16494.1 - 6.4e-08 32.6 0.0 1.3e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Ras PF00071.17 KKK16495.1 - 7.3e-43 145.7 0.3 3.4e-42 143.5 0.2 1.8 1 1 0 1 1 1 1 Ras family Miro PF08477.8 KKK16495.1 - 1.3e-11 44.9 0.0 2.2e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KKK16495.1 - 4.1e-05 22.8 0.2 0.00028 20.1 0.1 1.9 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KKK16495.1 - 0.0036 16.4 0.0 0.0049 16.0 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Pyridox_oxidase PF01243.15 KKK16496.1 - 1.3e-10 41.1 0.0 4.7e-10 39.3 0.0 1.9 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase PAPS_reduct PF01507.14 KKK16497.1 - 7.8e-44 149.5 0.1 1.8e-43 148.3 0.0 1.6 2 0 0 2 2 2 1 Phosphoadenosine phosphosulfate reductase family Ribosomal_S4e PF00900.15 KKK16498.1 - 7e-33 112.1 0.2 1.3e-32 111.2 0.2 1.5 1 0 0 1 1 1 1 Ribosomal family S4e RS4NT PF08071.7 KKK16498.1 - 5.6e-18 64.4 4.7 1.2e-17 63.4 3.3 1.6 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.20 KKK16498.1 - 4.6e-06 25.9 0.0 8.4e-06 25.1 0.0 1.5 1 0 0 1 1 1 1 S4 domain KOW PF00467.24 KKK16498.1 - 0.00034 20.2 3.7 0.00034 20.2 2.5 3.0 3 0 0 3 3 3 1 KOW motif PCI PF01399.22 KKK16499.1 - 6e-20 71.5 0.0 1.5e-19 70.2 0.0 1.7 1 0 0 1 1 1 1 PCI domain Asp_Glu_race_2 PF14669.1 KKK16499.1 - 0.061 12.6 0.2 0.17 11.1 0.1 1.8 2 0 0 2 2 2 0 Putative aspartate racemase PCI PF01399.22 KKK16500.1 - 1.2e-20 73.7 0.7 2.7e-20 72.6 0.1 1.9 2 0 0 2 2 2 1 PCI domain PCI_Csn8 PF10075.4 KKK16500.1 - 8.4e-07 28.8 0.1 1.7e-06 27.8 0.1 1.5 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 TPR_7 PF13176.1 KKK16500.1 - 0.0015 18.1 0.8 0.55 10.1 0.0 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 KKK16500.1 - 0.0015 18.2 2.3 0.17 11.8 0.0 4.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_10 PF13374.1 KKK16500.1 - 0.0036 17.1 0.3 0.98 9.4 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 KKK16500.1 - 0.0042 16.6 0.9 0.38 10.4 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat Ipi1_N PF12333.3 KKK16500.1 - 0.012 15.6 0.1 0.23 11.4 0.0 2.5 2 1 0 2 2 2 0 Rix1 complex component involved in 60S ribosome maturation TPR_12 PF13424.1 KKK16500.1 - 0.016 15.1 1.9 0.35 10.8 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 KKK16500.1 - 0.038 13.7 2.5 0.67 9.8 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.1 KKK16500.1 - 0.51 10.0 3.0 1.5 8.5 0.1 3.2 3 2 1 4 4 4 0 TPR repeat ATP-sulfurylase PF01747.12 KKK16501.1 - 2.8e-86 288.2 0.1 4.1e-86 287.7 0.0 1.2 1 0 0 1 1 1 1 ATP-sulfurylase APS_kinase PF01583.15 KKK16501.1 - 1.2e-60 203.6 0.0 1.9e-60 203.0 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase PUA_2 PF14306.1 KKK16501.1 - 5.7e-51 172.0 0.0 1e-50 171.2 0.0 1.4 1 0 0 1 1 1 1 PUA-like domain KTI12 PF08433.5 KKK16501.1 - 0.014 14.6 0.0 0.021 14.0 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_33 PF13671.1 KKK16501.1 - 0.017 15.0 0.4 0.032 14.1 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 KKK16501.1 - 0.11 12.8 0.0 0.56 10.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain Radical_SAM PF04055.16 KKK16502.1 - 1.9e-14 54.2 0.0 2.8e-14 53.6 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily HAD PF12710.2 KKK16503.1 - 1.6e-14 54.5 0.0 2.2e-14 54.0 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KKK16503.1 - 8.2e-11 42.7 0.2 4.8e-09 36.9 0.0 2.2 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KKK16503.1 - 1.2e-08 34.9 0.0 1.1e-06 28.4 0.0 2.8 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 KKK16503.1 - 6.9e-07 29.6 0.0 1.3e-05 25.4 0.0 2.4 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.7 KKK16503.1 - 4.3e-05 22.8 0.0 0.00017 20.8 0.0 1.8 1 1 0 1 1 1 1 Putative Phosphatase DUF705 PF05152.7 KKK16503.1 - 0.0023 16.9 0.2 0.0034 16.3 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF705) S6PP PF05116.8 KKK16503.1 - 0.035 13.4 0.1 0.46 9.7 0.0 2.1 2 0 0 2 2 2 0 Sucrose-6F-phosphate phosphohydrolase Semialdhyde_dhC PF02774.13 KKK16504.1 - 2.8e-32 112.0 0.0 3.8e-32 111.6 0.0 1.2 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.19 KKK16504.1 - 2.8e-30 105.1 0.0 5.8e-30 104.0 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.17 KKK16504.1 - 0.022 15.2 0.0 0.061 13.8 0.0 1.7 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold DapB_N PF01113.15 KKK16504.1 - 0.047 13.6 0.0 0.079 12.8 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus DXP_reductoisom PF02670.11 KKK16504.1 - 0.094 13.2 0.0 0.25 11.8 0.0 1.8 2 0 0 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase FAD-oxidase_C PF02913.14 KKK16505.1 - 9.4e-61 205.2 0.0 1.3e-60 204.8 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 KKK16505.1 - 3.5e-35 120.4 0.0 6.4e-35 119.6 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain SLA_LP_auto_ag PF05889.8 KKK16505.1 - 0.13 10.7 0.1 0.27 9.6 0.1 1.4 2 0 0 2 2 2 0 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) Macoilin PF09726.4 KKK16505.1 - 0.3 9.3 2.3 0.42 8.8 1.6 1.1 1 0 0 1 1 1 0 Transmembrane protein Alkyl_sulf_C PF14864.1 KKK16506.1 - 0.016 15.2 0.5 0.04 13.9 0.1 1.9 2 0 0 2 2 2 0 Alkyl sulfatase C-terminal ERM PF00769.14 KKK16506.1 - 0.37 10.2 56.9 0.14 11.7 12.7 2.5 2 1 1 3 3 3 0 Ezrin/radixin/moesin family Reo_sigmaC PF04582.7 KKK16506.1 - 0.38 9.8 15.9 0.34 10.0 0.5 3.3 1 1 2 3 3 3 0 Reovirus sigma C capsid protein Filament PF00038.16 KKK16506.1 - 3 7.2 49.9 3.7e+02 0.3 34.6 2.4 1 1 0 1 1 1 0 Intermediate filament protein GAS PF13851.1 KKK16506.1 - 6.6 5.8 50.9 11 5.0 17.1 3.5 1 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding Spc7 PF08317.6 KKK16506.1 - 8.5 4.9 48.6 1.1 7.8 11.1 3.2 1 1 2 3 3 3 0 Spc7 kinetochore protein RdRP PF05183.7 KKK16507.1 - 8.4e-151 503.5 0.0 2.5e-128 429.3 0.0 2.3 1 1 1 2 2 2 2 RNA dependent RNA polymerase RRM_1 PF00076.17 KKK16507.1 - 0.0091 15.6 0.0 0.026 14.1 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DNA_pol_B PF00136.16 KKK16508.1 - 3.4e-96 322.8 0.0 4.7e-96 322.3 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 KKK16508.1 - 6e-20 71.3 0.3 1.8e-10 40.1 0.0 2.5 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 KKK16508.1 - 1e-17 63.8 7.5 2.8e-17 62.4 5.2 1.8 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta Slu7 PF11708.3 KKK16509.1 - 8e-81 271.2 16.6 8e-81 271.2 11.5 1.6 2 0 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor Ribosomal_L37e PF01907.14 KKK16509.1 - 2.4e-12 46.4 2.3 2.4e-12 46.4 1.6 2.8 3 0 0 3 3 3 1 Ribosomal protein L37e zf-CCHC_4 PF14392.1 KKK16509.1 - 0.043 13.4 0.8 0.043 13.4 0.6 2.2 2 0 0 2 2 2 0 Zinc knuckle zf-ribbon_3 PF13248.1 KKK16509.1 - 0.2 10.9 3.2 3.1 7.1 0.2 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zf-HYPF PF07503.7 KKK16509.1 - 0.84 9.1 4.3 1 8.8 0.4 2.4 2 0 0 2 2 2 0 HypF finger Prothymosin PF03247.9 KKK16509.1 - 8.6 6.5 17.2 5.3 7.2 4.3 3.2 3 0 0 3 3 3 0 Prothymosin/parathymosin family DUF2348 PF09807.4 KKK16510.1 - 5.3e-05 22.4 0.0 0.00067 18.8 0.0 2.3 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2348) Fungal_trans PF04082.13 KKK16511.1 - 1.9e-30 105.5 0.1 2.9e-30 105.0 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK16511.1 - 7.4e-10 38.5 14.0 1.2e-09 37.8 9.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gal4_dimer PF03902.8 KKK16511.1 - 4.2e-05 23.3 0.1 0.0001 22.1 0.1 1.7 1 0 0 1 1 1 1 Gal4-like dimerisation domain Peptidase_C65 PF10275.4 KKK16512.1 - 2.5e-63 213.7 0.0 3e-63 213.4 0.0 1.1 1 0 0 1 1 1 1 Peptidase C65 Otubain Zn_clus PF00172.13 KKK16519.1 - 4.8e-09 35.9 9.6 9.3e-09 35.0 6.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KKK16519.1 - 6.6e-06 25.1 0.2 2e-05 23.6 0.1 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Vezatin PF12632.2 KKK16519.1 - 0.046 12.7 0.1 0.093 11.7 0.1 1.4 1 0 0 1 1 1 0 Mysoin-binding motif of peroxisomes Sugar_tr PF00083.19 KKK16520.1 - 8.6e-29 100.4 24.7 1.5e-28 99.6 17.1 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KKK16520.1 - 7e-14 51.3 31.7 7e-14 51.3 22.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily PhyH PF05721.8 KKK16521.1 - 1.9e-29 103.2 0.1 1.9e-29 103.2 0.1 1.4 2 0 0 2 2 2 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.1 KKK16521.1 - 9.6e-05 22.6 0.0 0.00021 21.5 0.0 1.6 1 0 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase Crystall PF00030.14 KKK16521.1 - 0.024 14.5 0.1 0.21 11.4 0.0 2.1 2 0 0 2 2 2 0 Beta/Gamma crystallin Phosphodiest PF01663.17 KKK16522.1 - 2.1e-28 99.7 0.0 4.1e-28 98.7 0.0 1.5 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase HD PF01966.17 KKK16522.1 - 5.7e-07 29.5 0.1 1.4e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 HD domain HDOD PF08668.7 KKK16522.1 - 0.0058 15.9 0.1 0.011 15.0 0.0 1.4 1 0 0 1 1 1 1 HDOD domain DUF706 PF05153.10 KKK16522.1 - 0.038 13.3 0.0 0.06 12.6 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF706) CFEM PF05730.6 KKK16523.1 - 7.9e-16 57.6 14.4 1.5e-15 56.7 9.9 1.5 1 0 0 1 1 1 1 CFEM domain GMC_oxred_N PF00732.14 KKK16524.1 - 4.1e-32 111.5 0.0 1.2e-28 100.1 0.0 2.4 2 1 0 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.8 KKK16524.1 - 3.3e-29 102.0 0.0 6.4e-29 101.1 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_3 PF13738.1 KKK16524.1 - 6.9e-05 22.9 0.1 0.26 11.3 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KKK16524.1 - 0.00024 21.0 0.1 0.00065 19.6 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KKK16524.1 - 0.00047 20.0 0.0 0.0013 18.6 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KKK16524.1 - 0.0011 17.9 0.0 0.0028 16.6 0.0 1.6 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 KKK16524.1 - 0.0034 16.2 1.0 0.01 14.7 0.6 1.7 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.19 KKK16524.1 - 0.012 14.5 1.2 0.18 10.6 0.6 2.4 2 0 0 2 2 2 0 FAD dependent oxidoreductase GIDA PF01134.17 KKK16524.1 - 0.014 14.2 0.2 0.43 9.3 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A ApbA PF02558.11 KKK16524.1 - 0.025 14.0 0.2 0.052 12.9 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA HHH PF00633.18 KKK16524.1 - 0.038 13.6 1.4 4.8 7.0 0.0 3.1 4 0 0 4 4 4 0 Helix-hairpin-helix motif 3HCDH_N PF02737.13 KKK16524.1 - 0.077 12.6 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.9 KKK16524.1 - 0.086 11.2 0.2 0.16 10.4 0.1 1.4 1 0 0 1 1 1 0 HI0933-like protein GidB PF02527.10 KKK16524.1 - 0.13 11.3 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G GDI PF00996.13 KKK16524.1 - 0.18 10.0 0.0 0.3 9.3 0.0 1.2 1 0 0 1 1 1 0 GDP dissociation inhibitor Peroxidase_2 PF01328.12 KKK16525.1 - 7.2e-16 57.7 1.7 4.1e-15 55.2 1.2 1.9 1 1 0 1 1 1 1 Peroxidase, family 2 Glyco_hydro_3 PF00933.16 KKK16525.1 - 0.15 10.9 0.0 0.56 9.1 0.0 1.7 1 1 1 2 2 2 0 Glycosyl hydrolase family 3 N terminal domain Trehalase PF01204.13 KKK16526.1 - 2.9e-73 247.2 0.0 2e-42 145.5 0.3 2.2 2 0 0 2 2 2 2 Trehalase Trehalase_Ca-bi PF07492.6 KKK16526.1 - 2.3e-10 39.5 0.2 3.9e-10 38.8 0.1 1.4 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain DUF1399 PF07173.7 KKK16527.1 - 6.7e-22 78.2 1.1 4.7e-18 65.7 0.1 2.8 2 0 0 2 2 2 2 Protein of unknown function (DUF1399) Bac_rhamnosid PF05592.6 KKK16528.1 - 0.073 11.2 0.1 0.11 10.7 0.0 1.2 1 0 0 1 1 1 0 Bacterial alpha-L-rhamnosidase SKG6 PF08693.5 KKK16529.1 - 0.0017 17.6 0.1 0.0047 16.2 0.1 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Gly-zipper_Omp PF13488.1 KKK16529.1 - 0.035 13.7 4.5 0.061 12.9 3.1 1.3 1 0 0 1 1 1 0 Glycine zipper MFS_1 PF07690.11 KKK16530.1 - 4.7e-30 104.4 34.0 4.7e-30 104.4 23.6 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KKK16530.1 - 1.1e-11 44.0 7.0 1.1e-11 44.0 4.8 2.8 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.11 KKK16531.1 - 2e-50 171.4 39.3 2.9e-50 170.9 27.3 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KKK16531.1 - 4.7e-12 45.2 18.3 4.7e-12 45.2 12.7 2.7 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_3 PF05977.8 KKK16531.1 - 0.00062 18.0 1.7 0.00062 18.0 1.2 1.7 2 0 0 2 2 2 1 Transmembrane secretion effector DUF2583 PF10762.4 KKK16531.1 - 5.1 7.2 7.6 0.42 10.7 1.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2583) FAD_binding_4 PF01565.18 KKK16532.1 - 4.3e-31 107.2 0.1 6.4e-31 106.6 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KKK16532.1 - 0.00093 19.0 0.2 0.0023 17.8 0.1 1.6 1 0 0 1 1 1 1 Berberine and berberine like Abhydrolase_6 PF12697.2 KKK16536.1 - 8.7e-22 78.1 0.8 6.3e-21 75.3 0.3 2.3 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KKK16536.1 - 2.1e-12 47.0 0.0 5.3e-12 45.7 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KKK16536.1 - 3e-12 46.6 0.0 4.9e-11 42.6 0.0 2.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.13 KKK16536.1 - 2.7e-07 30.1 0.0 0.086 12.1 0.0 3.2 3 0 0 3 3 3 3 Dienelactone hydrolase family Hydrolase_4 PF12146.3 KKK16536.1 - 1.3e-05 24.9 0.0 4.6e-05 23.1 0.0 1.9 2 0 0 2 2 2 1 Putative lysophospholipase FSH1 PF03959.8 KKK16536.1 - 0.0021 17.5 0.0 0.94 8.8 0.0 2.8 3 0 0 3 3 3 2 Serine hydrolase (FSH1) DUF2048 PF09752.4 KKK16536.1 - 0.0047 15.8 0.4 0.028 13.3 0.5 1.9 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2048) BAAT_C PF08840.6 KKK16536.1 - 0.022 14.4 0.3 0.25 11.0 0.0 2.2 2 1 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_3 PF07859.8 KKK16536.1 - 0.05 13.1 0.0 0.53 9.8 0.0 2.1 1 1 1 2 2 2 0 alpha/beta hydrolase fold Lipase_3 PF01764.20 KKK16536.1 - 0.1 12.2 0.1 0.35 10.4 0.0 1.8 2 0 0 2 2 2 0 Lipase (class 3) Cas_Csy4 PF09618.5 KKK16537.1 - 0.082 12.7 0.1 0.098 12.4 0.1 1.0 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csy4) WD40 PF00400.27 KKK16538.1 - 0.00036 20.3 1.3 0.21 11.5 0.0 4.2 4 1 0 4 4 4 1 WD domain, G-beta repeat Nucleoplasmin PF03066.10 KKK16538.1 - 0.036 13.5 2.9 0.072 12.6 2.0 1.5 1 0 0 1 1 1 0 Nucleoplasmin TFIIF_alpha PF05793.7 KKK16538.1 - 1 7.6 13.2 1.8 6.8 9.1 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) TLP-20 PF06088.6 KKK16538.1 - 1.4 8.6 4.6 0.29 10.7 0.9 1.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Nop14 PF04147.7 KKK16538.1 - 1.8 6.3 8.9 2.6 5.8 6.2 1.2 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 KKK16538.1 - 8.4 4.2 10.8 13 3.6 7.5 1.2 1 0 0 1 1 1 0 CDC45-like protein Glyco_hydro_7 PF00840.15 KKK16539.1 - 3.7e-210 697.7 20.3 4.3e-210 697.5 14.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 APG5 PF04106.7 KKK16540.1 - 8.4e-34 116.7 0.0 1.1e-33 116.3 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Apg5 ABC_tran PF00005.22 KKK16560.1 - 6.3e-26 91.3 0.1 1e-25 90.6 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.19 KKK16560.1 - 4.9e-25 87.9 27.0 7.1e-25 87.4 18.7 1.2 1 0 0 1 1 1 1 ABC-2 type transporter AAA_21 PF13304.1 KKK16560.1 - 4.5e-07 30.1 0.5 0.004 17.1 0.0 2.6 2 1 0 3 3 2 2 AAA domain AAA_16 PF13191.1 KKK16560.1 - 3.8e-05 23.7 0.1 7e-05 22.8 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.11 KKK16560.1 - 6.5e-05 22.1 0.0 0.00014 21.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_17 PF13207.1 KKK16560.1 - 8e-05 23.4 0.0 0.00019 22.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 KKK16560.1 - 9.6e-05 21.8 0.0 0.00038 19.9 0.0 1.8 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.14 KKK16560.1 - 0.00041 19.6 0.0 0.00081 18.6 0.0 1.4 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA PF00004.24 KKK16560.1 - 0.00044 20.4 0.1 0.0018 18.4 0.1 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 KKK16560.1 - 0.00045 20.0 0.0 0.0008 19.1 0.0 1.4 1 0 0 1 1 1 1 Archaeal ATPase AAA_15 PF13175.1 KKK16560.1 - 0.00082 18.5 0.0 0.056 12.4 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KKK16560.1 - 0.002 18.2 0.1 0.0066 16.5 0.1 1.9 1 1 0 1 1 1 1 AAA domain NACHT PF05729.7 KKK16560.1 - 0.0025 17.4 0.0 0.0051 16.4 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_19 PF13245.1 KKK16560.1 - 0.003 17.2 0.1 0.0063 16.2 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_14 PF13173.1 KKK16560.1 - 0.0036 17.2 0.0 0.0087 15.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 KKK16560.1 - 0.0041 17.0 0.2 0.0082 16.1 0.2 1.5 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 KKK16560.1 - 0.0043 16.4 0.0 0.011 15.1 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.1 KKK16560.1 - 0.0058 16.9 0.1 0.013 15.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.10 KKK16560.1 - 0.0066 15.1 0.0 0.01 14.5 0.0 1.2 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein RNA_helicase PF00910.17 KKK16560.1 - 0.009 16.1 0.0 0.026 14.6 0.0 1.8 1 0 0 1 1 1 1 RNA helicase AAA_33 PF13671.1 KKK16560.1 - 0.0094 15.8 0.0 0.017 14.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.10 KKK16560.1 - 0.018 14.7 0.1 0.081 12.6 0.0 2.0 2 0 0 2 2 2 0 NTPase MobB PF03205.9 KKK16560.1 - 0.021 14.5 0.0 0.036 13.7 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 KKK16560.1 - 0.024 14.5 0.1 0.058 13.3 0.1 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase PduV-EutP PF10662.4 KKK16560.1 - 0.029 13.8 0.0 0.077 12.4 0.0 1.7 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_13 PF13166.1 KKK16560.1 - 0.031 12.7 0.7 0.2 10.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 KKK16560.1 - 0.032 13.6 0.1 0.052 12.9 0.1 1.3 1 0 0 1 1 1 0 AAA-like domain T2SE PF00437.15 KKK16560.1 - 0.038 12.8 0.1 0.066 12.1 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein RuvB_N PF05496.7 KKK16560.1 - 0.041 12.9 0.0 0.071 12.1 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_29 PF13555.1 KKK16560.1 - 0.041 13.4 0.0 0.095 12.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain UPF0079 PF02367.12 KKK16560.1 - 0.045 13.3 0.1 0.093 12.3 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 ATP-synt_ab PF00006.20 KKK16560.1 - 0.067 12.6 0.1 0.13 11.7 0.1 1.4 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain NB-ARC PF00931.17 KKK16560.1 - 0.083 11.7 0.0 0.16 10.8 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain AAA_30 PF13604.1 KKK16560.1 - 0.093 12.2 0.1 0.18 11.3 0.1 1.4 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.1 KKK16560.1 - 0.095 12.6 0.0 0.36 10.7 0.0 2.1 2 1 0 2 2 1 0 Putative exonuclease SbcCD, C subunit ArgK PF03308.11 KKK16560.1 - 0.1 11.3 0.1 0.18 10.5 0.1 1.3 1 0 0 1 1 1 0 ArgK protein AAA_35 PF14516.1 KKK16560.1 - 0.12 11.0 0.0 0.19 10.3 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain cobW PF02492.14 KKK16560.1 - 0.15 11.5 0.1 0.27 10.6 0.1 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_5 PF07728.9 KKK16560.1 - 0.15 11.7 0.1 0.36 10.5 0.1 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) tRNA-synt_1d PF00750.14 KKK16561.1 - 5.5e-85 285.2 1.5 7.9e-85 284.7 1.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.10 KKK16561.1 - 3.9e-28 97.8 0.0 9.3e-28 96.5 0.0 1.7 1 0 0 1 1 1 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.11 KKK16561.1 - 6.1e-05 23.4 0.0 0.00023 21.6 0.0 2.1 2 0 0 2 2 2 1 Arginyl tRNA synthetase N terminal domain Acyl_transf_1 PF00698.16 KKK16568.1 - 2.5e-18 66.4 0.0 5.6e-12 45.6 0.0 2.1 2 0 0 2 2 2 2 Acyl transferase domain Nucleoporin_C PF03177.9 KKK16569.1 - 7.4e-132 440.8 8.7 9.7e-132 440.4 6.0 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 KKK16569.1 - 1.5e-75 254.5 0.0 2.4e-75 253.8 0.0 1.4 1 0 0 1 1 1 1 Nup133 N terminal like BsuPI PF12690.2 KKK16569.1 - 0.0065 16.1 0.0 1.9 8.2 0.0 3.4 3 0 0 3 3 3 1 Intracellular proteinase inhibitor IF-2B PF01008.12 KKK16570.1 - 3.1e-74 249.4 0.3 3.6e-74 249.2 0.2 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family Zip PF02535.17 KKK16571.1 - 0.05 12.6 0.2 0.063 12.2 0.1 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DUF2207 PF09972.4 KKK16571.1 - 0.069 11.7 0.1 0.076 11.5 0.0 1.3 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) JmjC PF02373.17 KKK16572.1 - 1.2e-08 35.1 0.3 1.8e-07 31.4 0.2 2.5 1 1 0 1 1 1 1 JmjC domain, hydroxylase zf-4CXXC_R1 PF10497.4 KKK16572.1 - 1.7e-08 34.5 9.4 1.7e-08 34.5 6.5 2.5 2 1 0 2 2 2 1 Zinc-finger domain of monoamine-oxidase A repressor R1 Cupin_2 PF07883.6 KKK16572.1 - 0.0082 15.6 0.0 0.027 13.9 0.0 1.8 2 0 0 2 2 2 1 Cupin domain UbiA PF01040.13 KKK16573.1 - 6.8e-34 117.2 19.0 9.1e-34 116.8 13.1 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Flavoprotein PF02441.14 KKK16574.1 - 3.1e-40 136.8 0.2 4.2e-40 136.4 0.1 1.2 1 0 0 1 1 1 1 Flavoprotein Ank_2 PF12796.2 KKK16575.1 - 1.5e-34 118.1 4.5 3.3e-16 59.3 0.0 5.0 2 1 3 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KKK16575.1 - 7.9e-25 86.7 10.6 5.6e-09 36.2 0.0 6.2 2 1 4 7 7 7 5 Ankyrin repeats (many copies) SPX PF03105.14 KKK16575.1 - 7.4e-24 84.9 6.5 8e-17 61.9 1.4 2.4 1 1 1 2 2 2 2 SPX domain Ank PF00023.25 KKK16575.1 - 1.3e-22 78.4 15.0 0.00011 21.7 0.0 7.5 8 0 0 8 8 8 5 Ankyrin repeat Ank_5 PF13857.1 KKK16575.1 - 5.7e-19 67.7 8.2 0.00021 21.4 0.0 6.5 1 1 5 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 KKK16575.1 - 4.9e-17 60.3 13.7 0.00098 19.1 0.0 8.4 10 0 0 10 10 10 4 Ankyrin repeat GDPD PF03009.12 KKK16575.1 - 6.4e-12 45.5 0.0 1.5e-11 44.3 0.0 1.6 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family DUF1279 PF06916.8 KKK16576.1 - 2.5e-27 95.0 0.0 4.4e-27 94.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) DUF4011 PF13195.1 KKK16576.1 - 0.07 13.1 0.2 0.097 12.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4011) Ribosomal_L3 PF00297.17 KKK16577.1 - 3.8e-37 128.1 3.6 9e-36 123.6 2.5 2.1 1 1 0 1 1 1 1 Ribosomal protein L3 Coa1 PF08695.5 KKK16578.1 - 7.9e-31 105.9 0.1 9.8e-31 105.6 0.1 1.1 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 DUF4307 PF14155.1 KKK16578.1 - 0.074 12.8 0.0 0.1 12.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4307) Oxidored_q6 PF01058.17 KKK16579.1 - 3.6e-22 78.3 0.0 5.7e-22 77.7 0.0 1.3 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Mpp10 PF04006.7 KKK16580.1 - 2.6e-93 313.4 36.7 3.4e-93 313.0 25.4 1.1 1 0 0 1 1 1 1 Mpp10 protein Methyltransf_16 PF10294.4 KKK16581.1 - 6.9e-49 165.6 0.0 9.7e-49 165.1 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 KKK16581.1 - 0.097 13.2 0.0 0.2 12.2 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 KKK16581.1 - 0.13 11.6 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain DUF1761 PF08570.5 KKK16582.1 - 5.6e-24 84.5 3.5 6.3e-24 84.3 2.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1761) PhaG_MnhG_YufB PF03334.9 KKK16582.1 - 0.7 9.9 4.4 7.2 6.7 3.0 2.7 1 1 0 1 1 1 0 Na+/H+ antiporter subunit AhpC-TSA PF00578.16 KKK16584.1 - 1.1e-23 83.2 0.0 3.8e-23 81.4 0.0 1.7 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 KKK16584.1 - 1.8e-12 46.9 0.0 2.8e-12 46.4 0.0 1.3 1 1 0 1 1 1 1 Redoxin PRELI PF04707.9 KKK16585.1 - 6.8e-45 152.4 0.3 7.9e-45 152.2 0.2 1.0 1 0 0 1 1 1 1 PRELI-like family Mycobact_memb PF05423.8 KKK16585.1 - 0.052 13.2 0.1 0.08 12.6 0.0 1.3 1 0 0 1 1 1 0 Mycobacterium membrane protein CTP_transf_2 PF01467.21 KKK16587.1 - 3.2e-19 69.5 0.0 1.8e-16 60.5 0.0 2.4 2 0 0 2 2 2 2 Cytidylyltransferase Glutaredoxin PF00462.19 KKK16588.1 - 4e-15 55.5 0.0 6.9e-15 54.7 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin Cwf_Cwc_15 PF04889.7 KKK16595.1 - 5.8e-82 275.0 11.1 8.8e-82 274.4 7.7 1.2 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein Med22 PF06179.7 KKK16595.1 - 2.6e-22 78.8 2.6 2.6e-22 78.8 1.8 2.1 2 1 1 3 3 3 1 Surfeit locus protein 5 subunit 22 of Mediator complex DUF2890 PF11081.3 KKK16595.1 - 0.49 10.4 13.8 0.027 14.5 5.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2890) Glyco_hydro_4C PF11975.3 KKK16595.1 - 6 6.5 6.9 24 4.6 0.0 2.2 2 0 0 2 2 2 0 Family 4 glycosyl hydrolase C-terminal domain RNase_PH PF01138.16 KKK16596.1 - 1.4e-16 60.9 0.0 2.2e-16 60.3 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 KKK16596.1 - 0.00017 21.4 0.0 0.00039 20.3 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 DHFR_1 PF00186.14 KKK16597.1 - 4.1e-19 68.7 0.0 6.6e-07 29.0 0.0 3.2 2 1 1 3 3 3 3 Dihydrofolate reductase Mito_fiss_reg PF05308.6 KKK16597.1 - 0.15 11.3 1.7 0.2 10.9 1.2 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator E1-E2_ATPase PF00122.15 KKK16598.1 - 8.6e-18 64.2 0.1 1.6e-17 63.2 0.0 1.4 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 KKK16598.1 - 8.9e-18 65.1 0.1 2.4e-17 63.7 0.0 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KKK16598.1 - 8e-12 46.0 2.8 1.8e-10 41.5 2.0 2.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KKK16598.1 - 1.4e-11 44.1 0.0 3.6e-11 42.8 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KKK16598.1 - 0.0041 16.7 0.0 0.015 14.8 0.0 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 KKK16598.1 - 0.013 15.7 0.2 0.05 13.8 0.0 2.0 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase DUF2838 PF10998.3 KKK16604.1 - 5.3e-44 148.6 10.9 5.3e-44 148.6 7.6 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF2838) Tropomyosin_1 PF12718.2 KKK16604.1 - 0.01 15.6 1.1 0.018 14.8 0.8 1.3 1 0 0 1 1 1 0 Tropomyosin like Atg14 PF10186.4 KKK16604.1 - 0.021 13.7 2.5 0.035 13.0 1.8 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Tropomyosin PF00261.15 KKK16604.1 - 0.081 12.0 2.6 0.14 11.2 1.8 1.3 1 0 0 1 1 1 0 Tropomyosin Val_tRNA-synt_C PF10458.4 KKK16604.1 - 0.58 10.2 6.9 9.2 6.4 0.0 2.4 2 0 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm LETM1 PF07766.8 KKK16605.1 - 6.8e-105 349.9 0.1 6.8e-105 349.9 0.1 1.4 2 0 0 2 2 2 1 LETM1-like protein SAP PF02037.22 KKK16605.1 - 9.1e-06 25.0 0.0 0.0033 16.8 0.0 3.3 3 0 0 3 3 3 2 SAP domain FAA_hydrolase PF01557.13 KKK16607.1 - 6e-50 169.7 0.0 7.3e-50 169.4 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family PWI PF01480.12 KKK16608.1 - 2.2e-27 94.9 0.0 3.7e-27 94.2 0.0 1.4 1 0 0 1 1 1 1 PWI domain Cupin_8 PF13621.1 KKK16609.1 - 3.3e-16 59.5 0.1 1.4e-14 54.1 0.1 2.2 1 1 0 1 1 1 1 Cupin-like domain JmjC PF02373.17 KKK16609.1 - 5.2e-10 39.5 0.3 1e-08 35.3 0.2 2.3 1 1 0 1 1 1 1 JmjC domain, hydroxylase F-box-like PF12937.2 KKK16609.1 - 3.7e-07 29.7 0.1 7.3e-07 28.8 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KKK16609.1 - 1.9e-05 24.1 0.0 4.4e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 F-box domain DEAD PF00270.24 KKK16610.1 - 6e-44 149.5 1.4 8.3e-44 149.0 0.5 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KKK16610.1 - 8.1e-28 96.1 0.4 2.9e-27 94.3 0.1 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KKK16610.1 - 0.0024 17.7 0.0 0.0073 16.1 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 KKK16610.1 - 0.0042 17.2 0.2 0.016 15.3 0.2 1.9 1 1 0 1 1 1 1 AAA domain CMS1 PF14617.1 KKK16610.1 - 0.0044 16.1 0.0 0.01 14.9 0.0 1.5 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit AAA_30 PF13604.1 KKK16610.1 - 0.01 15.4 0.0 0.031 13.8 0.0 1.8 2 1 0 2 2 2 0 AAA domain AAA_19 PF13245.1 KKK16610.1 - 0.017 14.8 0.1 0.061 13.0 0.1 1.9 1 1 0 1 1 1 0 Part of AAA domain CobA_CobO_BtuR PF02572.10 KKK16610.1 - 0.082 12.5 0.1 0.16 11.5 0.1 1.4 1 0 0 1 1 1 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP Fanconi_A PF03511.9 KKK16610.1 - 0.095 12.4 0.1 0.22 11.3 0.1 1.5 1 0 0 1 1 1 0 Fanconi anaemia group A protein NuA4 PF09340.5 KKK16611.1 - 1.1e-28 98.7 0.6 1.1e-28 98.7 0.4 1.8 2 0 0 2 2 2 1 Histone acetyltransferase subunit NuA4 4HBT_3 PF13622.1 KKK16611.1 - 0.034 13.8 0.4 0.051 13.3 0.3 1.2 1 0 0 1 1 1 0 Thioesterase-like superfamily Serglycin PF04360.7 KKK16611.1 - 2.1 8.0 16.0 0.28 10.9 0.1 2.6 3 0 0 3 3 3 0 Serglycin Tmemb_cc2 PF10267.4 KKK16611.1 - 3.5 6.0 13.1 1.1 7.7 0.3 1.9 1 1 1 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein Ctr PF04145.10 KKK16612.1 - 2.9e-37 127.9 1.4 3.4e-37 127.6 1.0 1.1 1 0 0 1 1 1 1 Ctr copper transporter family DUF454 PF04304.8 KKK16612.1 - 0.044 13.8 0.5 0.044 13.8 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF454) Wzy_C PF04932.10 KKK16612.1 - 0.36 10.6 4.0 12 5.7 0.0 2.1 1 1 1 2 2 2 0 O-Antigen ligase Glyco_hydro_38 PF01074.17 KKK16614.1 - 5.8e-92 307.8 1.0 5.8e-92 307.8 0.7 2.0 3 0 0 3 3 3 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.8 KKK16614.1 - 4.3e-72 243.3 0.0 1.2e-71 241.8 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.6 KKK16614.1 - 8.7e-26 89.9 0.0 1.7e-25 88.9 0.0 1.5 1 0 0 1 1 1 1 Alpha mannosidase, middle domain Glyco_hydro_18 PF00704.23 KKK16615.1 - 3.4e-40 138.5 0.4 5.7e-40 137.8 0.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 LysM PF01476.15 KKK16615.1 - 3.8e-10 39.4 0.0 1e-05 25.3 0.0 2.8 2 0 0 2 2 2 2 LysM domain Chitin_bind_1 PF00187.14 KKK16615.1 - 0.0021 18.0 3.6 0.0021 18.0 2.5 2.8 2 0 0 2 2 2 1 Chitin recognition protein Amidohydro_1 PF01979.15 KKK16616.1 - 6.4e-09 35.9 0.0 9.8e-09 35.3 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 KKK16616.1 - 8.8e-07 28.4 0.0 9.9e-07 28.3 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 KKK16616.1 - 7e-05 22.9 0.0 0.0001 22.4 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase Bcr-Abl_Oligo PF09036.5 KKK16616.1 - 0.098 12.6 0.1 0.19 11.6 0.1 1.4 1 0 0 1 1 1 0 Bcr-Abl oncoprotein oligomerisation domain ATG22 PF11700.3 KKK16617.1 - 4.2e-164 546.5 8.9 5.3e-131 437.3 3.2 2.0 1 1 1 2 2 2 2 Vacuole effluxer Atg22 like MFS_1 PF07690.11 KKK16617.1 - 2.1e-05 23.4 20.9 2.1e-05 23.4 14.5 3.3 2 1 1 3 3 3 2 Major Facilitator Superfamily BT1 PF03092.11 KKK16617.1 - 0.00034 19.4 4.5 0.00058 18.6 3.1 1.4 1 0 0 1 1 1 1 BT1 family PBP PF01161.15 KKK16618.1 - 1.3e-19 70.4 0.0 1.7e-19 70.1 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein GFA PF04828.9 KKK16619.1 - 6.9e-22 77.2 0.0 9.9e-22 76.7 0.0 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme zf-ribbon_3 PF13248.1 KKK16619.1 - 0.052 12.7 0.3 0.53 9.5 0.0 2.6 3 0 0 3 3 3 0 zinc-ribbon domain Nudix_N_2 PF14803.1 KKK16619.1 - 0.13 11.9 0.1 0.13 11.9 0.0 2.8 3 0 0 3 3 3 0 Nudix N-terminal zinc_ribbon_2 PF13240.1 KKK16619.1 - 0.26 10.8 0.1 0.26 10.8 0.0 2.2 3 0 0 3 3 3 0 zinc-ribbon domain DZR PF12773.2 KKK16619.1 - 0.31 10.8 2.8 0.43 10.4 0.7 2.2 2 1 0 2 2 2 0 Double zinc ribbon Lar_restr_allev PF14354.1 KKK16619.1 - 2.6 8.4 5.3 3.5 7.9 1.1 2.5 2 1 0 2 2 2 0 Restriction alleviation protein Lar Zn_clus PF00172.13 KKK16620.1 - 8.3e-09 35.2 7.3 3.6e-08 33.1 5.1 2.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KKK16620.1 - 1e-05 24.5 0.2 1.9e-05 23.7 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain OPT PF03169.10 KKK16621.1 - 2e-187 624.4 53.9 2.3e-187 624.2 37.4 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF754 PF05449.6 KKK16621.1 - 0.051 13.6 1.6 0.26 11.3 0.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF754) TcdA_TcdB_pore PF12920.2 KKK16621.1 - 0.2 9.5 0.0 0.28 9.0 0.0 1.1 1 0 0 1 1 1 0 TcdA/TcdB pore forming domain NADH_B2 PF14813.1 KKK16621.1 - 0.38 10.4 9.7 5.9 6.6 0.1 3.9 3 0 0 3 3 3 0 NADH dehydrogenase 1 beta subcomplex subunit 2 p450 PF00067.17 KKK16622.1 - 1.8e-105 353.1 0.0 2.1e-105 352.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 PBP PF01161.15 KKK16624.1 - 4.9e-10 39.4 0.1 8.8e-10 38.6 0.1 1.4 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Zn_clus PF00172.13 KKK16624.1 - 2.2e-08 33.8 11.0 7.7e-08 32.1 7.7 2.0 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 KKK16625.1 - 4.5e-45 153.8 22.1 4.5e-45 153.8 15.3 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KKK16625.1 - 4.6e-14 51.8 1.8 4.6e-14 51.8 1.3 2.3 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 KKK16625.1 - 1.3e-05 23.6 3.2 1.3e-05 23.6 2.2 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF791 PF05631.9 KKK16625.1 - 0.021 13.5 4.2 0.018 13.7 0.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF791) MFS_1_like PF12832.2 KKK16625.1 - 0.03 14.0 0.5 0.03 14.0 0.3 4.1 4 1 2 6 6 6 0 MFS_1 like family DUF3464 PF11947.3 KKK16625.1 - 0.16 11.4 0.0 0.58 9.6 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3464) DUF3353 PF11833.3 KKK16625.1 - 0.18 11.2 4.7 0.69 9.3 2.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3353) MFS_3 PF05977.8 KKK16625.1 - 5 5.1 13.9 0.12 10.4 4.8 1.8 2 0 0 2 2 2 0 Transmembrane secretion effector Citrate_synt PF00285.16 KKK16626.1 - 1.6e-81 273.7 0.0 1.9e-81 273.5 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase Fungal_trans PF04082.13 KKK16627.1 - 1.2e-36 125.9 0.0 1.9e-36 125.2 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK16627.1 - 1e-09 38.1 8.9 1.7e-09 37.4 6.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RNA_pol PF00940.14 KKK16628.1 - 1.5e-169 563.8 0.0 1.9e-169 563.4 0.0 1.2 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.1 KKK16628.1 - 2.2e-77 260.4 0.3 3.5e-77 259.7 0.2 1.3 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal Ras PF00071.17 KKK16629.1 - 2.7e-59 199.1 0.2 3.5e-59 198.7 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KKK16629.1 - 8e-21 74.7 0.0 1.2e-20 74.1 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KKK16629.1 - 1.5e-17 63.3 0.1 1.8e-17 63.1 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KKK16629.1 - 2.5e-07 30.3 0.0 1.1e-06 28.1 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 KKK16629.1 - 2.6e-06 26.7 0.0 3.8e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 KKK16629.1 - 4e-06 26.1 0.1 5e-06 25.8 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KKK16629.1 - 1.1e-05 25.3 0.0 2.4e-05 24.2 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 KKK16629.1 - 0.02 14.6 0.1 2.9 7.6 0.0 2.6 2 1 1 3 3 3 0 Dynamin family AAA_14 PF13173.1 KKK16629.1 - 0.043 13.7 0.2 0.085 12.7 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 KKK16629.1 - 0.12 12.2 0.0 3.1 7.7 0.0 2.1 1 1 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.1 KKK16629.1 - 0.13 12.4 0.0 1.1 9.3 0.0 2.3 1 1 0 1 1 1 0 AAA domain ATP-synt_C PF00137.16 KKK16630.1 - 2.1e-26 91.5 23.8 5.6e-16 58.1 4.9 2.3 2 0 0 2 2 2 2 ATP synthase subunit C Lysis_S PF04971.7 KKK16630.1 - 0.088 12.5 2.3 0.18 11.5 0.0 2.5 3 0 0 3 3 3 0 Lysis protein S Oxidored_q2 PF00420.19 KKK16630.1 - 1 8.9 8.1 0.83 9.2 2.7 2.7 1 1 1 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L NIR_SIR PF01077.17 KKK16631.1 - 3.8e-48 162.8 0.0 3.6e-42 143.3 0.0 2.4 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.12 KKK16631.1 - 5.8e-30 102.7 0.0 3.7e-14 52.0 0.0 2.7 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.20 KKK16631.1 - 1.9e-25 89.5 0.0 4.3e-25 88.3 0.0 1.7 1 0 0 1 1 1 1 Flavodoxin Sin_N PF04801.8 KKK16631.1 - 2.2e-21 76.2 0.0 3.1e-20 72.4 0.0 2.1 1 1 0 1 1 1 1 Sin-like protein conserved region POR_N PF01855.14 KKK16631.1 - 2.2e-08 33.8 0.5 1.1e-07 31.6 0.0 2.1 2 0 0 2 2 2 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg Kei1 PF08552.6 KKK16632.1 - 1.9e-59 200.5 0.5 2.3e-59 200.2 0.3 1.1 1 0 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 DDHD PF02862.12 KKK16633.1 - 1.5e-46 159.0 1.1 1.9e-27 96.5 0.0 3.1 2 2 1 3 3 3 2 DDHD domain Abhydrolase_5 PF12695.2 KKK16633.1 - 0.024 14.4 0.0 0.067 12.9 0.0 1.7 1 0 0 1 1 1 0 Alpha/beta hydrolase family LSM PF01423.17 KKK16637.1 - 6.1e-14 51.3 1.0 9.3e-14 50.7 0.7 1.3 1 0 0 1 1 1 1 LSM domain DRMBL PF07522.9 KKK16638.1 - 1.8e-34 118.0 0.0 4e-34 116.9 0.0 1.6 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.2 KKK16638.1 - 6.3e-12 45.4 0.0 1.4e-11 44.3 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Rad50_zn_hook PF04423.9 KKK16638.1 - 0.026 13.9 0.0 0.061 12.7 0.0 1.6 1 0 0 1 1 1 0 Rad50 zinc hook motif SH3BGR PF04908.10 KKK16639.1 - 0.0022 17.9 0.0 0.0091 15.9 0.0 2.1 2 0 0 2 2 2 1 SH3-binding, glutamic acid-rich protein Pneumo_att_G PF05539.6 KKK16639.1 - 7.1 5.9 8.7 8.4 5.6 6.0 1.2 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G Ribul_P_3_epim PF00834.14 KKK16640.1 - 9.7e-64 214.1 0.0 1.2e-62 210.5 0.0 2.0 1 1 0 1 1 1 1 Ribulose-phosphate 3 epimerase family QRPTase_C PF01729.14 KKK16640.1 - 0.004 16.6 0.0 0.74 9.3 0.0 2.2 2 0 0 2 2 2 2 Quinolinate phosphoribosyl transferase, C-terminal domain ThiG PF05690.9 KKK16640.1 - 0.024 13.6 0.1 0.037 13.1 0.1 1.2 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG OMPdecase PF00215.19 KKK16640.1 - 0.034 13.5 0.1 0.048 13.0 0.0 1.5 1 1 0 1 1 1 0 Orotidine 5'-phosphate decarboxylase / HUMPS family Amidohydro_2 PF04909.9 KKK16640.1 - 0.074 12.6 0.6 0.53 9.7 0.2 2.3 1 1 1 2 2 2 0 Amidohydrolase Methyltransf_11 PF08241.7 KKK16641.1 - 6.3e-07 29.8 0.0 1.5e-06 28.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KKK16641.1 - 0.0033 17.1 0.0 0.01 15.5 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain adh_short_C2 PF13561.1 KKK16643.1 - 3.1e-32 112.2 0.0 3.5e-32 112.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KKK16643.1 - 2.8e-27 95.6 0.3 3.5e-27 95.3 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KKK16643.1 - 6.3e-14 52.0 0.1 8.5e-14 51.6 0.0 1.1 1 0 0 1 1 1 1 KR domain Death PF00531.17 KKK16643.1 - 0.15 11.8 0.0 0.34 10.7 0.0 1.6 1 0 0 1 1 1 0 Death domain PAS_9 PF13426.1 KKK16645.1 - 7.6e-20 71.2 0.0 7.3e-17 61.6 0.0 3.1 3 0 0 3 3 3 2 PAS domain PAS_4 PF08448.5 KKK16645.1 - 0.00015 21.8 1.9 0.25 11.3 0.0 3.4 3 0 0 3 3 3 2 PAS fold PAS PF00989.19 KKK16645.1 - 0.00066 19.4 9.5 0.001 18.8 0.0 3.7 4 0 0 4 4 4 1 PAS fold Hid1 PF12722.2 KKK16645.1 - 0.063 10.9 8.1 0.089 10.4 5.6 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Spore_coat_CotO PF14153.1 KKK16645.1 - 0.29 10.5 16.8 0.49 9.8 11.7 1.3 1 0 0 1 1 1 0 Spore coat protein CotO DUF4259 PF14078.1 KKK16645.1 - 0.56 10.6 7.4 1.3 9.5 5.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4259) PAT1 PF09770.4 KKK16645.1 - 0.8 7.8 21.5 1.1 7.4 14.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 LMBR1 PF04791.11 KKK16645.1 - 1.4 7.3 3.4 1.9 6.9 2.4 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Ycf1 PF05758.7 KKK16645.1 - 1.6 6.3 6.6 2.4 5.7 4.6 1.3 1 0 0 1 1 1 0 Ycf1 MFS_1 PF07690.11 KKK16646.1 - 5.2e-22 78.0 39.4 1.9e-19 69.5 19.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KKK16646.1 - 1.3e-05 23.6 2.4 2.1e-05 22.9 1.7 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) TPR_11 PF13414.1 KKK16647.1 - 2.2e-15 56.0 1.0 3.9e-06 26.4 0.0 4.2 4 0 0 4 4 4 3 TPR repeat TPR_2 PF07719.12 KKK16647.1 - 9.6e-14 50.1 2.1 0.0013 18.4 0.0 5.7 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_1 PF00515.23 KKK16647.1 - 2.8e-11 42.5 2.5 0.00035 20.0 0.0 5.3 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.1 KKK16647.1 - 1e-08 35.5 12.4 0.041 14.5 0.3 6.3 6 1 1 7 7 7 4 Tetratricopeptide repeat TPR_14 PF13428.1 KKK16647.1 - 2.4e-06 27.6 11.0 3.7 8.4 0.0 7.6 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_12 PF13424.1 KKK16647.1 - 3.6e-06 26.8 8.5 0.22 11.4 0.3 5.4 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.1 KKK16647.1 - 4.1e-06 27.0 5.0 1.9 8.8 0.3 5.6 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.1 KKK16647.1 - 0.0029 17.2 0.0 8.6 6.3 0.0 4.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_4 PF07721.9 KKK16647.1 - 0.01 16.1 9.2 0.73 10.4 0.2 5.6 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_9 PF13371.1 KKK16647.1 - 0.077 12.8 8.0 3.8 7.4 0.0 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat LSM PF01423.17 KKK16648.1 - 7.7e-19 67.0 0.0 9.1e-19 66.7 0.0 1.1 1 0 0 1 1 1 1 LSM domain Tannase PF07519.6 KKK16650.1 - 4.9e-101 338.7 0.0 6.3e-101 338.4 0.0 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_5 PF12695.2 KKK16650.1 - 0.0011 18.6 0.0 0.024 14.4 0.0 2.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KKK16650.1 - 0.0011 18.5 0.0 0.0021 17.6 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KKK16650.1 - 0.0014 18.5 0.0 0.0053 16.6 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KKK16650.1 - 0.0093 15.2 0.1 1.9 7.6 0.1 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family DUF866 PF05907.8 KKK16651.1 - 6.3e-43 146.0 1.5 1.8e-42 144.5 1.1 1.6 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) FAD_binding_3 PF01494.14 KKK16652.1 - 1e-70 238.5 0.0 1.3e-70 238.2 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 KKK16652.1 - 2.2e-39 134.7 0.1 4e-39 133.9 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain DAO PF01266.19 KKK16652.1 - 0.0029 16.5 0.0 0.032 13.1 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KKK16652.1 - 0.0089 16.4 0.0 0.04 14.3 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KKK16652.1 - 0.022 13.6 0.1 0.12 11.2 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox_2 PF07992.9 KKK16652.1 - 0.08 12.8 0.0 0.27 11.0 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GDI PF00996.13 KKK16652.1 - 0.11 10.7 0.0 0.16 10.2 0.0 1.2 1 0 0 1 1 1 0 GDP dissociation inhibitor Thi4 PF01946.12 KKK16652.1 - 0.16 10.9 0.0 0.3 10.1 0.0 1.3 1 0 0 1 1 1 0 Thi4 family RIX1 PF08167.7 KKK16653.1 - 1.3e-57 194.0 0.7 4.5e-57 192.3 0.5 2.0 1 0 0 1 1 1 1 rRNA processing/ribosome biogenesis TPR_2 PF07719.12 KKK16654.1 - 3.7e-10 38.9 9.4 0.023 14.5 0.0 6.7 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_11 PF13414.1 KKK16654.1 - 7.9e-08 31.8 10.3 0.00024 20.6 0.0 5.1 4 1 1 5 5 5 3 TPR repeat TPR_14 PF13428.1 KKK16654.1 - 2.3e-07 30.8 20.1 3.4 8.5 0.0 8.8 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_1 PF00515.23 KKK16654.1 - 3.2e-07 29.6 7.4 0.0063 16.0 0.0 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.1 KKK16654.1 - 2.2e-06 27.0 3.5 7 6.6 0.0 5.9 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 KKK16654.1 - 0.00011 22.0 14.5 0.67 9.9 0.0 5.2 4 1 0 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.1 KKK16654.1 - 0.00013 22.5 18.1 1 10.0 0.0 6.2 5 1 0 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.1 KKK16654.1 - 0.00049 19.6 7.4 1.3 8.9 0.0 6.1 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.1 KKK16654.1 - 0.0011 19.2 6.1 2.7 8.3 0.0 5.5 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.1 KKK16654.1 - 0.0018 18.3 0.3 15 6.0 0.0 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.1 KKK16654.1 - 0.0028 17.5 3.1 7.6 6.6 0.0 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat NDUFA12 PF05071.11 KKK16655.1 - 3.2e-27 95.0 0.8 4.2e-27 94.6 0.6 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 PLDc_2 PF13091.1 KKK16656.1 - 7.2e-14 51.6 0.0 1.6e-07 31.1 0.0 2.2 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.17 KKK16656.1 - 3.6e-07 29.7 1.1 0.025 14.3 0.3 3.3 2 1 0 2 2 2 2 Phospholipase D Active site motif DnaG_DnaB_bind PF08278.6 KKK16656.1 - 0.1 12.7 0.0 0.28 11.4 0.0 1.6 2 0 0 2 2 2 0 DNA primase DnaG DnaB-binding SNF2_N PF00176.18 KKK16657.1 - 6.2e-42 143.4 0.0 3.5e-40 137.6 0.0 2.3 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KKK16657.1 - 1.1e-13 50.8 0.0 2.6e-13 49.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KKK16657.1 - 0.00015 21.6 0.1 0.0024 17.7 0.0 2.8 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.3 KKK16657.1 - 0.0064 15.3 0.1 0.034 12.9 0.0 2.2 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 SAM_1 PF00536.25 KKK16657.1 - 0.015 15.4 0.1 0.044 13.9 0.1 1.8 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) SNF2_N PF00176.18 KKK16658.1 - 6.5e-71 238.5 0.0 9.2e-71 238.0 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.6 KKK16658.1 - 3.5e-15 55.8 0.0 7.1e-15 54.8 0.0 1.6 1 0 0 1 1 1 1 HIRAN domain zf-RING_2 PF13639.1 KKK16658.1 - 8.9e-11 41.4 7.7 2.4e-10 40.0 5.4 1.8 1 0 0 1 1 1 1 Ring finger domain Helicase_C PF00271.26 KKK16658.1 - 2.8e-09 36.6 0.1 1.1e-08 34.7 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.1 KKK16658.1 - 4.6e-09 36.1 10.2 8.7e-09 35.2 5.4 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KKK16658.1 - 4.1e-08 32.7 8.2 2e-07 30.5 4.3 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KKK16658.1 - 4.4e-08 32.6 8.3 4.4e-08 32.6 5.7 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KKK16658.1 - 1.8e-07 30.9 8.8 2.2e-07 30.6 5.0 2.0 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-Nse PF11789.3 KKK16658.1 - 3.6e-07 29.6 7.1 4.6e-07 29.2 4.1 1.8 2 0 0 2 2 1 1 Zinc-finger of the MIZ type in Nse subunit zf-rbx1 PF12678.2 KKK16658.1 - 1.7e-06 28.0 3.1 6e-06 26.2 2.1 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 KKK16658.1 - 7.7e-06 25.5 6.0 1.9e-05 24.2 4.2 1.7 1 0 0 1 1 1 1 zinc-RING finger domain U-box PF04564.10 KKK16658.1 - 8e-06 25.7 0.1 4.7e-05 23.2 0.0 2.2 2 0 0 2 2 2 1 U-box domain zf-Apc11 PF12861.2 KKK16658.1 - 0.00011 21.9 0.5 0.00025 20.8 0.4 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 KKK16658.1 - 0.001 18.7 4.9 0.001 18.7 3.4 2.4 3 0 0 3 3 2 1 RING-type zinc-finger Pterin_bind PF00809.17 KKK16658.1 - 0.11 11.9 0.1 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 Pterin binding enzyme zf-RING_4 PF14570.1 KKK16658.1 - 0.52 9.9 5.6 1.9 8.1 4.0 1.9 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain DUF1644 PF07800.7 KKK16658.1 - 1.2 8.9 6.5 7 6.4 0.0 2.5 2 1 1 3 3 2 0 Protein of unknown function (DUF1644) MFS_1 PF07690.11 KKK16659.1 - 2.3e-43 148.2 43.8 2.3e-43 148.2 30.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KKK16659.1 - 3.8e-06 25.7 28.5 9.8e-05 21.0 19.7 2.5 1 1 0 1 1 1 1 Sugar (and other) transporter MBOAT_2 PF13813.1 KKK16660.1 - 2.5e-21 75.5 4.5 7.2e-21 74.0 3.1 1.8 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family GSH_synth_ATP PF03917.12 KKK16661.1 - 2.6e-88 296.1 0.0 3.4e-86 289.1 0.0 2.0 1 1 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.10 KKK16661.1 - 1.7e-30 105.2 0.0 3.1e-30 104.3 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic glutathione synthase DUF3733 PF12534.3 KKK16681.1 - 0.53 9.6 4.3 0.18 11.1 0.6 2.0 2 0 0 2 2 2 0 Leucine-rich repeat containing protein 8 WD40 PF00400.27 KKK16687.1 - 2.4e-62 204.7 26.7 5.6e-11 41.8 0.2 8.1 7 2 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 KKK16687.1 - 0.00067 17.9 4.6 0.01 14.0 0.2 3.7 2 2 1 5 5 5 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 KKK16687.1 - 0.063 12.0 1.2 0.65 8.6 0.2 2.6 2 1 1 3 3 3 0 Nup133 N terminal like Cytochrom_D1 PF02239.11 KKK16687.1 - 0.11 10.8 0.3 1.5 7.0 0.0 2.3 2 1 0 2 2 2 0 Cytochrome D1 heme domain B-block_TFIIIC PF04182.7 KKK16688.1 - 7.2e-22 77.0 0.2 7e-21 73.8 0.0 2.5 3 0 0 3 3 3 1 B-block binding subunit of TFIIIC MarR_2 PF12802.2 KKK16688.1 - 0.0042 16.7 2.5 0.031 13.9 0.0 3.1 3 0 0 3 3 3 1 MarR family DUF1180 PF06679.7 KKK16689.1 - 0.24 11.2 3.5 0.27 11.1 2.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Methyltransf_PK PF05891.7 KKK16690.1 - 1e-68 230.9 0.0 1.2e-68 230.7 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_23 PF13489.1 KKK16690.1 - 6.2e-08 32.5 0.0 8.2e-08 32.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KKK16690.1 - 3.7e-06 27.4 0.0 5.4e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KKK16690.1 - 0.00015 22.1 0.0 0.00023 21.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KKK16690.1 - 0.0017 18.8 0.0 0.0027 18.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KKK16690.1 - 0.058 13.7 0.0 0.091 13.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Sulfate_tra_GLY PF13792.1 KKK16691.1 - 0.084 12.5 0.2 0.084 12.5 0.2 1.8 2 0 0 2 2 2 0 Sulfate transporter N-terminal domain with GLY motif ABC2_membrane_2 PF12679.2 KKK16691.1 - 3.2 6.5 10.5 1 8.1 0.8 2.3 2 1 0 2 2 2 0 ABC-2 family transporter protein SET PF00856.23 KKK16692.1 - 6.6e-23 81.7 0.0 1.2e-22 80.9 0.0 1.4 1 0 0 1 1 1 1 SET domain adh_short PF00106.20 KKK16693.1 - 9.5e-19 67.9 0.1 1.8e-18 66.9 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KKK16693.1 - 2.3e-08 34.1 0.0 3.4e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KKK16693.1 - 4.1e-08 33.0 0.0 6e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KKK16693.1 - 0.0006 19.8 0.1 0.002 18.1 0.0 1.9 2 0 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 KKK16693.1 - 0.0085 15.5 0.0 0.015 14.7 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 KKK16693.1 - 0.015 15.4 0.0 0.03 14.4 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Polysacc_synt_2 PF02719.10 KKK16693.1 - 0.047 12.5 0.0 0.068 12.0 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Pro-kuma_activ PF09286.6 KKK16697.1 - 2.5e-41 141.0 1.0 4.4e-41 140.2 0.3 1.7 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 KKK16697.1 - 4.9e-07 29.1 0.0 8.1e-07 28.4 0.0 1.3 1 0 0 1 1 1 1 Subtilase family Lyase_8_N PF08124.6 KKK16697.1 - 0.0051 15.7 0.0 0.0076 15.1 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide lyase family 8, N terminal alpha-helical domain Phytase-like PF13449.1 KKK16698.1 - 1.9e-28 99.7 0.0 6.8e-28 97.8 0.0 1.8 1 1 0 1 1 1 1 Esterase-like activity of phytase Trypan_PARP PF05887.6 KKK16698.1 - 9.6 6.0 21.9 0.22 11.3 7.0 2.6 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) TBCC PF07986.7 KKK16699.1 - 2.3e-33 114.1 1.5 3e-33 113.7 0.6 1.6 2 0 0 2 2 2 1 Tubulin binding cofactor C Coatomer_WDAD PF04053.9 KKK16700.1 - 6.4e-152 506.3 0.0 2e-151 504.8 0.0 1.7 2 0 0 2 2 2 1 Coatomer WD associated region COPI_C PF06957.6 KKK16700.1 - 1e-92 310.8 0.0 1.7e-92 310.2 0.0 1.2 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.27 KKK16700.1 - 6.3e-51 168.5 11.1 2.9e-09 36.4 0.1 7.2 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 KKK16700.1 - 0.015 13.4 6.8 1.7 6.6 0.5 3.8 2 1 1 3 3 3 0 Nucleoporin Nup120/160 Clathrin PF00637.15 KKK16700.1 - 0.017 14.7 0.3 0.3 10.6 0.0 2.8 3 0 0 3 3 3 0 Region in Clathrin and VPS LysR_substrate PF03466.15 KKK16700.1 - 0.082 11.9 0.0 0.18 10.9 0.0 1.5 1 0 0 1 1 1 0 LysR substrate binding domain DUF3504 PF12012.3 KKK16702.1 - 4.4 7.0 10.8 32 4.2 7.5 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF3504) Evr1_Alr PF04777.8 KKK16703.1 - 1.8e-25 88.6 0.9 1.8e-25 88.6 0.6 1.5 2 0 0 2 2 2 1 Erv1 / Alr family SAC3_GANP PF03399.11 KKK16704.1 - 9.8e-26 90.5 0.0 1.2e-25 90.2 0.0 1.1 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 KKK16704.1 - 6.6e-21 74.5 0.0 1.2e-20 73.7 0.0 1.4 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 DUF4170 PF13773.1 KKK16705.1 - 0.18 11.6 0.0 0.46 10.4 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4170) Adaptin_N PF01602.15 KKK16706.1 - 2.8e-148 494.5 5.9 3.5e-148 494.1 4.1 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 KKK16706.1 - 2.9e-30 105.4 0.9 1.1e-26 93.7 0.1 3.1 2 1 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 KKK16706.1 - 1.1e-20 73.6 1.6 5.9e-06 26.4 0.0 6.2 2 1 4 6 6 6 4 HEAT repeats HEAT PF02985.17 KKK16706.1 - 4.6e-12 44.9 3.8 0.016 15.2 0.0 7.2 7 0 0 7 7 7 3 HEAT repeat HEAT_EZ PF13513.1 KKK16706.1 - 1.8e-05 25.0 0.2 2 9.0 0.0 6.4 6 1 1 7 7 7 1 HEAT-like repeat CLASP_N PF12348.3 KKK16706.1 - 0.00012 21.5 0.6 2 7.7 0.0 4.3 3 1 2 5 5 5 2 CLASP N terminal Arm PF00514.18 KKK16706.1 - 0.0014 18.3 0.9 8.3 6.4 0.0 5.3 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat UNC45-central PF11701.3 KKK16706.1 - 0.042 13.4 0.3 0.15 11.7 0.1 2.1 2 1 0 2 2 2 0 Myosin-binding striated muscle assembly central Atx10homo_assoc PF09759.4 KKK16706.1 - 0.072 12.8 0.0 1.7 8.3 0.0 2.9 2 1 0 2 2 2 0 Spinocerebellar ataxia type 10 protein domain ADH_N PF08240.7 KKK16707.1 - 5.4e-20 71.1 4.9 9.3e-20 70.4 3.4 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KKK16707.1 - 2.7e-16 59.3 0.0 4.5e-16 58.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KKK16707.1 - 8.1e-07 29.9 0.0 1.5e-06 29.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 KKK16707.1 - 0.0035 16.5 0.0 0.0054 15.8 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Thr_synth_N PF14821.1 KKK16708.1 - 1.6e-30 104.9 0.0 1e-29 102.3 0.0 2.3 2 0 0 2 2 2 1 Threonine synthase N terminus PALP PF00291.20 KKK16708.1 - 6.8e-16 58.3 0.0 2.2e-15 56.6 0.0 1.7 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Hexapep PF00132.19 KKK16709.1 - 3.5e-10 38.9 10.4 0.00021 20.6 2.2 4.5 3 1 2 5 5 5 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 KKK16709.1 - 2.4e-06 26.9 4.9 3.7e-05 23.1 0.3 3.2 2 1 1 3 3 3 2 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.7 KKK16709.1 - 0.012 14.2 0.0 0.014 13.9 0.0 1.1 1 0 0 1 1 1 0 L-fucokinase RXT2_N PF08595.6 KKK16720.1 - 2.4e-42 144.2 0.1 2.4e-42 144.2 0.1 2.1 2 0 0 2 2 2 1 RXT2-like, N-terminal Sigma70_ner PF04546.8 KKK16720.1 - 0.38 10.3 9.3 2.6 7.5 0.2 2.6 2 0 0 2 2 2 0 Sigma-70, non-essential region Rhomboid PF01694.17 KKK16721.1 - 9.4e-24 84.1 7.2 1.9e-23 83.1 5.0 1.5 1 0 0 1 1 1 1 Rhomboid family Golgin_A5 PF09787.4 KKK16722.1 - 0.00067 18.2 0.9 0.00068 18.2 0.6 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 5 DUF3439 PF11921.3 KKK16722.1 - 0.0011 18.6 3.5 0.0018 17.9 2.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3439) IncA PF04156.9 KKK16722.1 - 0.0033 17.0 2.2 0.004 16.7 1.5 1.1 1 0 0 1 1 1 1 IncA protein Atg14 PF10186.4 KKK16722.1 - 0.0055 15.6 0.8 0.0066 15.4 0.6 1.1 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 Syntaxin PF00804.20 KKK16722.1 - 0.036 14.2 1.5 0.05 13.7 1.0 1.3 1 0 0 1 1 1 0 Syntaxin Dicty_REP PF05086.7 KKK16722.1 - 0.045 11.5 5.1 0.074 10.7 3.5 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Tropomyosin PF00261.15 KKK16722.1 - 0.047 12.7 3.5 0.065 12.3 2.4 1.2 1 0 0 1 1 1 0 Tropomyosin MCR_alpha PF02249.12 KKK16722.1 - 0.053 13.5 0.5 0.069 13.1 0.3 1.2 1 0 0 1 1 1 0 Methyl-coenzyme M reductase alpha subunit, C-terminal domain Flu_PA PF00603.12 KKK16722.1 - 0.066 11.2 1.1 0.073 11.0 0.7 1.0 1 0 0 1 1 1 0 Influenza RNA-dependent RNA polymerase subunit PA DUF1779 PF08680.5 KKK16722.1 - 0.19 11.5 4.2 0.28 11.0 2.9 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1779) Striatin PF08232.7 KKK16722.1 - 0.21 11.8 4.0 0.54 10.5 2.3 1.8 1 1 1 2 2 2 0 Striatin family DivIC PF04977.10 KKK16722.1 - 0.39 10.2 1.9 16 5.0 0.3 2.2 1 1 1 2 2 2 0 Septum formation initiator ATG16 PF08614.6 KKK16722.1 - 0.45 10.2 6.2 0.1 12.4 1.8 1.7 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) SSP160 PF06933.6 KKK16722.1 - 0.76 7.6 9.8 0.99 7.3 6.8 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Tropomyosin_1 PF12718.2 KKK16722.1 - 0.83 9.4 7.9 0.72 9.7 4.8 1.5 1 1 0 1 1 1 0 Tropomyosin like Mob1_phocein PF03637.12 KKK16723.1 - 1.1e-30 106.6 3.4 1.5e-14 54.0 0.0 2.2 2 0 0 2 2 2 2 Mob1/phocein family Leo1 PF04004.8 KKK16724.1 - 1.8e-32 112.4 0.0 2.9e-32 111.7 0.0 1.4 1 0 0 1 1 1 1 Leo1-like protein DUF2890 PF11081.3 KKK16724.1 - 0.41 10.6 8.7 2.7 8.0 5.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2890) Zn_clus PF00172.13 KKK16725.1 - 6.5e-09 35.5 8.5 1.9e-08 34.0 5.9 1.9 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BOP1NT PF08145.7 KKK16726.1 - 1.2e-106 356.2 7.3 1.7e-106 355.7 5.1 1.2 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.27 KKK16726.1 - 7e-08 32.0 0.1 0.00038 20.2 0.0 4.1 5 0 0 5 5 5 2 WD domain, G-beta repeat PhoD PF09423.5 KKK16728.1 - 1.3e-13 50.3 0.0 8.9e-09 34.4 0.1 2.2 2 0 0 2 2 2 2 PhoD-like phosphatase Gryzun PF07919.7 KKK16729.1 - 9.4e-145 483.0 2.5 1.4e-144 482.5 0.3 1.9 2 0 0 2 2 2 1 Gryzun, putative trafficking through Golgi Foie-gras_1 PF11817.3 KKK16729.1 - 6.8e-87 291.0 4.1 2.1e-77 259.9 2.9 3.5 3 1 0 3 3 3 2 Foie gras liver health family 1 TPR_19 PF14559.1 KKK16729.1 - 0.095 13.0 0.1 23 5.4 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Gryzun-like PF12742.2 KKK16729.1 - 0.16 11.7 0.0 0.35 10.7 0.0 1.5 1 0 0 1 1 1 0 Gryzun, putative Golgi trafficking Glutaredoxin PF00462.19 KKK16730.1 - 1.9e-14 53.3 0.2 1.3e-13 50.7 0.0 2.2 2 0 0 2 2 2 1 Glutaredoxin GST_N_3 PF13417.1 KKK16730.1 - 0.12 12.5 0.4 0.32 11.2 0.0 1.9 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain Abhydrolase_6 PF12697.2 KKK16731.1 - 7.1e-19 68.5 0.3 3.1e-18 66.4 0.2 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KKK16731.1 - 1.2e-09 38.0 0.1 0.00043 20.0 0.0 2.6 3 0 0 3 3 3 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KKK16731.1 - 4e-07 29.8 0.0 7.7e-07 28.8 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF3336 PF11815.3 KKK16732.1 - 7.6e-39 132.5 0.1 1.4e-38 131.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 KKK16732.1 - 6.2e-17 62.2 2.8 1.3e-16 61.1 0.5 2.1 2 0 0 2 2 2 1 Patatin-like phospholipase Ribosomal_L6 PF00347.18 KKK16733.1 - 9.6e-24 83.6 3.5 3.3e-11 43.5 0.8 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 BPS PF08947.5 KKK16749.1 - 0.038 13.6 0.1 0.17 11.5 0.0 2.1 2 0 0 2 2 2 0 BPS (Between PH and SH2) SnoaL_2 PF12680.2 KKK16750.1 - 3.6e-05 24.0 0.0 4.4e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain MFS_1 PF07690.11 KKK16751.1 - 5.7e-27 94.3 30.5 5.7e-27 94.3 21.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily CAP_GLY PF01302.20 KKK16752.1 - 3.3e-16 58.7 0.9 6.9e-16 57.7 0.6 1.5 1 0 0 1 1 1 1 CAP-Gly domain TMF_DNA_bd PF12329.3 KKK16752.1 - 0.00013 21.7 25.6 0.22 11.3 3.0 5.1 5 0 0 5 5 5 2 TATA element modulatory factor 1 DNA binding AAA_13 PF13166.1 KKK16752.1 - 0.0012 17.4 10.8 0.0033 15.9 4.0 2.1 1 1 1 2 2 2 1 AAA domain Reo_sigmaC PF04582.7 KKK16752.1 - 0.0073 15.5 3.5 4.4 6.3 0.2 3.1 2 1 1 3 3 3 1 Reovirus sigma C capsid protein Gp58 PF07902.6 KKK16752.1 - 0.014 13.6 0.7 0.023 12.9 0.5 1.4 1 0 0 1 1 1 0 gp58-like protein Seryl_tRNA_N PF02403.17 KKK16752.1 - 0.014 15.3 9.3 0.83 9.6 1.7 3.6 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain NPV_P10 PF05531.7 KKK16752.1 - 0.02 15.1 9.8 1.1 9.5 0.2 3.5 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein IncA PF04156.9 KKK16752.1 - 0.033 13.7 36.5 0.22 11.1 9.4 3.3 2 1 1 3 3 3 0 IncA protein YajC PF02699.10 KKK16752.1 - 0.33 10.6 0.9 0.75 9.5 0.1 2.0 2 0 0 2 2 2 0 Preprotein translocase subunit Occludin_ELL PF07303.8 KKK16752.1 - 0.33 11.7 10.3 2 9.2 1.8 3.4 3 0 0 3 3 3 0 Occludin homology domain BLOC1_2 PF10046.4 KKK16752.1 - 0.83 9.8 11.5 0.22 11.6 1.0 3.5 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 EzrA PF06160.7 KKK16752.1 - 0.91 7.6 21.1 0.0099 14.1 5.7 2.7 2 1 1 3 3 3 0 Septation ring formation regulator, EzrA Spc7 PF08317.6 KKK16752.1 - 0.96 8.0 19.9 1.9 7.0 2.9 3.1 2 1 1 3 3 3 0 Spc7 kinetochore protein PilJ PF13675.1 KKK16752.1 - 1.3 9.3 22.0 0.04 14.2 2.3 4.4 2 1 2 4 4 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF812 PF05667.6 KKK16752.1 - 2 6.8 13.9 2.8 6.3 7.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF812) SlyX PF04102.7 KKK16752.1 - 5 7.5 21.0 0.35 11.2 3.4 4.0 3 0 0 3 3 3 0 SlyX DUF745 PF05335.8 KKK16752.1 - 5.3 6.5 9.6 0.19 11.2 1.2 2.3 3 0 0 3 3 2 0 Protein of unknown function (DUF745) V_ATPase_I PF01496.14 KKK16752.1 - 5.6 4.6 15.9 2.8 5.6 0.0 3.0 2 1 1 3 3 3 0 V-type ATPase 116kDa subunit family DUF16 PF01519.11 KKK16752.1 - 5.7 7.2 10.1 21 5.4 0.1 3.8 4 0 0 4 4 4 0 Protein of unknown function DUF16 Mod_r PF07200.8 KKK16752.1 - 6 6.7 21.3 2.1 8.2 4.3 3.2 2 1 1 3 3 3 0 Modifier of rudimentary (Mod(r)) protein Pkinase PF00069.20 KKK16753.1 - 5.9e-36 123.9 0.0 3.1e-22 78.9 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KKK16753.1 - 1.6e-13 50.3 0.0 2.2e-12 46.6 0.0 2.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KKK16753.1 - 0.0015 17.5 0.0 1.2 7.9 0.0 2.3 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 KKK16753.1 - 0.009 15.7 0.0 0.028 14.1 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family SLAC1 PF03595.12 KKK16755.1 - 2.2e-67 227.0 30.9 5.5e-41 140.3 14.0 2.0 1 1 1 2 2 2 2 Voltage-dependent anion channel RTC_insert PF05189.8 KKK16756.1 - 5.5e-31 106.6 0.0 1e-30 105.7 0.0 1.5 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain RTC PF01137.16 KKK16756.1 - 2.5e-29 101.6 0.0 3.6e-29 101.1 0.0 1.1 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase 3-HAO PF06052.7 KKK16757.1 - 4.1e-44 149.6 0.0 5.4e-44 149.2 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.6 KKK16757.1 - 0.00049 19.5 0.0 0.0008 18.8 0.0 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.17 KKK16757.1 - 0.0041 16.5 0.0 0.0075 15.7 0.0 1.4 1 0 0 1 1 1 1 Cupin DZR PF12773.2 KKK16757.1 - 0.031 14.1 2.9 0.044 13.6 1.0 2.0 2 1 0 2 2 2 0 Double zinc ribbon Plant_tran PF04827.9 KKK16757.1 - 0.032 13.5 0.1 0.042 13.2 0.0 1.3 1 0 0 1 1 1 0 Plant transposon protein zf-ribbon_3 PF13248.1 KKK16757.1 - 0.23 10.7 7.5 1.8 7.8 0.1 2.6 3 0 0 3 3 3 0 zinc-ribbon domain Nudix_N_2 PF14803.1 KKK16757.1 - 0.36 10.5 4.6 9.3 6.0 0.2 2.5 1 1 3 4 4 4 0 Nudix N-terminal ADK_lid PF05191.9 KKK16757.1 - 0.84 9.3 5.9 9 6.0 0.1 3.0 3 0 0 3 3 3 0 Adenylate kinase, active site lid TF_Zn_Ribbon PF08271.7 KKK16757.1 - 1 8.7 5.1 3.9 6.8 0.1 3.1 1 1 2 3 3 3 0 TFIIB zinc-binding RRN7 PF11781.3 KKK16757.1 - 2.8 7.5 6.5 15 5.2 0.1 2.9 2 1 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 SpoIIE PF07228.7 KKK16758.1 - 1.6e-11 44.2 0.2 3.8e-10 39.8 0.1 2.1 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 KKK16758.1 - 1.2e-09 37.9 0.1 2.1e-09 37.1 0.1 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.16 KKK16758.1 - 1e-07 31.6 0.0 0.0054 16.1 0.0 2.3 2 0 0 2 2 2 2 Protein phosphatase 2C WD40 PF00400.27 KKK16759.1 - 6.7e-49 162.1 20.0 5.1e-09 35.6 0.1 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat PRP4 PF08799.6 KKK16759.1 - 1.9e-15 55.8 4.8 3.2e-15 55.0 3.3 1.4 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like PRTP PF01366.13 KKK16759.1 - 0.16 9.9 0.6 0.23 9.4 0.4 1.1 1 0 0 1 1 1 0 Herpesvirus processing and transport protein HSCB_C PF07743.8 KKK16760.1 - 2.3e-20 72.8 0.0 1.6e-19 70.1 0.0 2.0 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.26 KKK16760.1 - 3.4e-09 36.2 0.0 6.4e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain Glyco_hydro_43 PF04616.9 KKK16761.1 - 2.3e-29 102.3 4.1 5.4e-29 101.1 2.9 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 P_proprotein PF01483.15 KKK16761.1 - 0.0095 15.7 0.1 0.22 11.3 0.0 2.3 2 0 0 2 2 2 1 Proprotein convertase P-domain Zn_clus PF00172.13 KKK16788.1 - 0.00099 18.9 6.0 0.0015 18.3 4.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AT_hook PF02178.14 KKK16788.1 - 0.088 12.5 6.8 0.28 10.9 4.7 1.9 1 0 0 1 1 1 0 AT hook motif DUF1746 PF08508.5 KKK16812.1 - 1.1e-42 144.6 1.3 1.6e-42 144.0 0.9 1.3 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1746) Peptidase_M18 PF02127.10 KKK16813.1 - 8.3e-159 528.6 0.0 9.5e-159 528.5 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) SMC_N PF02463.14 KKK16815.1 - 4.5e-60 202.6 0.0 7.5e-59 198.6 0.0 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 KKK16815.1 - 9.2e-32 109.5 0.0 4e-31 107.4 0.0 2.2 2 0 0 2 2 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 KKK16815.1 - 2.6e-12 47.2 1.2 5.4e-08 33.1 0.1 3.6 5 0 0 5 5 5 2 AAA domain AAA_29 PF13555.1 KKK16815.1 - 1.4e-08 34.1 0.0 2.8e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain IncA PF04156.9 KKK16815.1 - 0.00048 19.7 14.9 0.00048 19.7 10.4 7.0 3 2 5 8 8 7 1 IncA protein SbcCD_C PF13558.1 KKK16815.1 - 0.0013 18.5 0.1 0.013 15.3 0.0 2.9 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit MAD PF05557.8 KKK16815.1 - 0.0013 16.8 30.6 0.0013 16.8 21.2 4.1 3 1 1 4 4 4 2 Mitotic checkpoint protein AAA_23 PF13476.1 KKK16815.1 - 0.0031 17.8 106.6 0.057 13.7 0.4 6.5 2 2 1 4 4 3 1 AAA domain AAA_22 PF13401.1 KKK16815.1 - 0.09 12.9 4.6 6.7 6.8 0.0 4.9 4 1 1 5 5 5 0 AAA domain DUF3407 PF11887.3 KKK16815.1 - 0.19 11.0 2.8 0.99 8.6 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3407) Reo_sigmaC PF04582.7 KKK16815.1 - 0.83 8.7 19.5 2.3 7.3 0.2 4.6 4 1 2 6 6 6 0 Reovirus sigma C capsid protein WD40 PF00400.27 KKK16816.1 - 7.5e-36 120.7 7.0 1.6e-07 30.9 0.1 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 KKK16816.1 - 5.8e-08 32.6 0.1 0.0089 15.7 0.0 3.1 2 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A ATPgrasp_ST PF14397.1 KKK16816.1 - 0.058 12.4 0.0 0.085 11.9 0.0 1.1 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp E3_binding PF02817.12 KKK16817.1 - 1.4e-06 27.7 0.2 2.6e-05 23.7 0.0 2.6 2 0 0 2 2 2 1 e3 binding domain MRP_L53 PF10780.4 KKK16819.1 - 1.8e-19 69.4 0.1 2.5e-19 68.9 0.0 1.2 1 0 0 1 1 1 1 39S ribosomal protein L53/MRP-L53 Pyrophosphatase PF00719.14 KKK16820.1 - 3.7e-52 175.8 0.2 5.1e-52 175.4 0.1 1.2 1 0 0 1 1 1 1 Inorganic pyrophosphatase Dus PF01207.12 KKK16821.1 - 1.2e-43 149.1 0.1 2.9e-43 147.8 0.1 1.6 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) COX5A PF02284.11 KKK16821.1 - 0.018 14.9 0.0 0.039 13.9 0.0 1.5 1 0 0 1 1 1 0 Cytochrome c oxidase subunit Va PrmA PF06325.8 KKK16821.1 - 0.14 11.2 0.0 0.31 10.1 0.0 1.5 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) Glyco_transf_8 PF01501.15 KKK16822.1 - 2.6e-12 46.6 0.0 2.9e-12 46.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl transferase family 8 MHYT PF03707.11 KKK16861.1 - 2.1e-10 40.5 20.2 4.7e-06 26.6 1.4 4.5 4 0 0 4 4 4 3 Bacterial signalling protein N terminal repeat OTU PF02338.14 KKK16862.1 - 4.2e-12 46.7 0.1 1.6e-11 44.8 0.1 1.9 1 1 0 1 1 1 1 OTU-like cysteine protease CUE PF02845.11 KKK16862.1 - 0.0092 15.4 0.0 0.029 13.8 0.0 1.8 1 0 0 1 1 1 1 CUE domain Amidohydro_1 PF01979.15 KKK16863.1 - 6.9e-38 131.1 0.0 9e-38 130.7 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 KKK16863.1 - 8.2e-12 45.0 0.1 1.4e-07 31.1 0.0 2.2 1 1 0 2 2 2 2 Amidohydrolase family Amidohydro_4 PF13147.1 KKK16863.1 - 1.2e-07 32.0 0.2 0.0016 18.5 0.1 2.3 2 0 0 2 2 2 2 Amidohydrolase Amidohydro_5 PF13594.1 KKK16863.1 - 4e-06 26.5 0.0 1.1e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 Amidohydrolase A_deaminase PF00962.17 KKK16863.1 - 0.00043 19.3 0.0 0.0029 16.5 0.0 2.0 1 1 1 2 2 2 1 Adenosine/AMP deaminase COPI_assoc PF08507.5 KKK16864.1 - 3.6e-46 156.2 8.0 4e-46 156.1 5.6 1.0 1 0 0 1 1 1 1 COPI associated protein Cg6151-P PF10233.4 KKK16864.1 - 1.7 8.6 11.4 2.4 8.1 6.1 2.0 1 1 1 2 2 2 0 Uncharacterized conserved protein CG6151-P ExoD PF06055.7 KKK16864.1 - 1.9 7.5 6.2 10 5.1 3.0 2.0 2 0 0 2 2 2 0 Exopolysaccharide synthesis, ExoD Rhomboid PF01694.17 KKK16864.1 - 4.2 7.3 15.4 4.9 7.1 10.7 1.1 1 0 0 1 1 1 0 Rhomboid family DUF3784 PF12650.2 KKK16864.1 - 6.5 6.7 13.1 0.6 10.0 3.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3784) DAO PF01266.19 KKK16865.1 - 6.4e-28 97.6 0.0 7.9e-28 97.3 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KKK16865.1 - 0.0004 20.3 0.0 0.0012 18.8 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KKK16865.1 - 0.011 14.8 1.8 0.014 14.4 0.0 2.1 2 0 0 2 2 2 0 Thi4 family adh_short PF00106.20 KKK16866.1 - 2e-34 118.9 0.0 2.8e-34 118.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KKK16866.1 - 1.6e-15 57.5 0.0 2.2e-15 57.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KKK16866.1 - 1.6e-13 50.7 0.0 2.6e-13 50.0 0.0 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 KKK16866.1 - 0.0012 17.8 0.1 0.0024 16.8 0.0 1.6 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 KKK16866.1 - 0.0035 16.8 0.0 0.0068 15.8 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.5 KKK16866.1 - 0.01 15.0 0.0 0.017 14.3 0.0 1.3 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Eno-Rase_NADH_b PF12242.3 KKK16866.1 - 0.027 14.2 0.1 0.065 13.0 0.0 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_10 PF13460.1 KKK16866.1 - 0.16 12.0 0.6 0.44 10.5 0.2 2.0 2 1 0 2 2 2 0 NADH(P)-binding GATA PF00320.22 KKK16867.1 - 2e-30 103.8 17.5 5e-16 57.7 4.0 2.5 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.7 KKK16867.1 - 1.3e-05 24.3 3.1 0.0067 15.7 0.0 2.4 2 0 0 2 2 2 2 TFIIB zinc-binding zf-ribbon_3 PF13248.1 KKK16867.1 - 0.0075 15.4 8.4 0.35 10.1 0.5 2.8 2 1 0 2 2 2 2 zinc-ribbon domain Auto_anti-p27 PF06677.7 KKK16867.1 - 0.018 14.7 4.4 0.21 11.3 0.2 2.4 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) eIF-5_eIF-2B PF01873.12 KKK16867.1 - 0.053 13.1 3.2 2.7 7.6 0.1 2.3 2 0 0 2 2 2 0 Domain found in IF2B/IF5 Zn-ribbon_8 PF09723.5 KKK16867.1 - 0.063 13.2 2.7 1.3 9.0 0.2 2.6 2 0 0 2 2 2 0 Zinc ribbon domain DZR PF12773.2 KKK16867.1 - 0.46 10.3 14.8 6.4e+02 0.2 10.1 3.2 1 1 0 1 1 1 0 Double zinc ribbon ArfGap PF01412.13 KKK16867.1 - 0.56 10.0 4.4 0.83 9.4 0.1 2.3 2 0 0 2 2 2 0 Putative GTPase activating protein for Arf Ribonuc_L-PSP PF01042.16 KKK16869.1 - 2.7e-33 114.3 0.0 3.1e-33 114.1 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP Fe-ADH PF00465.14 KKK16869.1 - 0.005 15.5 0.1 0.006 15.2 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Rab3-GTPase_cat PF13890.1 KKK16869.1 - 0.082 12.2 0.0 0.12 11.7 0.0 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein catalytic subunit Cation_efflux PF01545.16 KKK16870.1 - 5.1e-76 255.4 6.6 6.3e-76 255.1 4.6 1.0 1 0 0 1 1 1 1 Cation efflux family BPD_transp_2 PF02653.11 KKK16870.1 - 0.019 13.9 0.4 0.019 13.9 0.3 2.0 2 1 0 2 2 2 0 Branched-chain amino acid transport system / permease component SH3_1 PF00018.23 KKK16871.1 - 3.6e-25 87.0 0.0 3.3e-11 42.3 0.0 2.8 3 0 0 3 3 3 2 SH3 domain SH3_9 PF14604.1 KKK16871.1 - 3.4e-15 55.3 0.1 3.1e-07 29.8 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain PX PF00787.19 KKK16871.1 - 2.5e-13 49.7 0.0 6.7e-13 48.4 0.0 1.7 2 0 0 2 2 2 1 PX domain SH3_2 PF07653.12 KKK16871.1 - 6.6e-10 38.3 0.0 8.6e-06 25.1 0.0 2.9 3 0 0 3 3 3 2 Variant SH3 domain PB1 PF00564.19 KKK16871.1 - 2.7e-09 36.5 0.6 5.4e-09 35.6 0.4 1.5 1 0 0 1 1 1 1 PB1 domain AFG1_ATPase PF03969.11 KKK16872.1 - 1e-93 314.0 0.0 1.9e-88 296.7 0.0 2.1 2 0 0 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.1 KKK16872.1 - 0.00021 21.3 0.0 0.22 11.4 0.0 2.8 2 1 1 3 3 3 2 AAA ATPase domain AAA_14 PF13173.1 KKK16872.1 - 0.0026 17.6 0.0 0.0059 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 KKK16872.1 - 0.0069 16.5 0.0 0.019 15.1 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KKK16872.1 - 0.017 14.8 0.0 0.036 13.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Bac_DnaA PF00308.13 KKK16872.1 - 0.029 14.0 0.1 2.3 7.8 0.1 2.5 2 1 0 2 2 2 0 Bacterial dnaA protein RNA_helicase PF00910.17 KKK16872.1 - 0.034 14.3 0.0 0.14 12.3 0.0 2.2 1 0 0 1 1 1 0 RNA helicase AAA_22 PF13401.1 KKK16872.1 - 0.057 13.5 0.0 0.15 12.1 0.0 1.8 1 1 0 1 1 1 0 AAA domain MTP18 PF10558.4 KKK16873.1 - 5.1e-69 230.9 0.1 6.6e-69 230.5 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) Uricase PF01014.13 KKK16894.1 - 2e-87 290.3 2.7 5e-49 165.9 0.4 2.0 2 0 0 2 2 2 2 Uricase Mob_Pre PF01076.14 KKK16894.1 - 0.04 13.5 0.0 0.069 12.7 0.0 1.3 1 0 0 1 1 1 0 Plasmid recombination enzyme dCMP_cyt_deam_1 PF00383.17 KKK16895.1 - 1.5e-11 43.8 0.0 7.2e-11 41.6 0.0 2.0 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region APOBEC_N PF08210.6 KKK16895.1 - 0.0023 17.5 0.0 0.0031 17.1 0.0 1.4 1 1 0 1 1 1 1 APOBEC-like N-terminal domain Bd3614-deam PF14439.1 KKK16895.1 - 0.058 13.2 0.1 0.26 11.1 0.0 2.1 1 1 1 2 2 2 0 Bd3614-like deaminase zf-H2C2_2 PF13465.1 KKK16896.1 - 2.6e-07 30.5 12.0 9.9e-06 25.5 1.1 2.9 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 KKK16896.1 - 2.7e-06 27.2 13.9 0.00019 21.5 4.3 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-Di19 PF05605.7 KKK16896.1 - 0.00041 20.4 3.9 0.00071 19.6 2.7 1.3 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.21 KKK16896.1 - 0.0038 17.4 16.8 0.018 15.3 4.6 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 KKK16896.1 - 0.0043 17.1 4.7 0.058 13.5 0.7 2.4 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding Zn_Tnp_IS1595 PF12760.2 KKK16896.1 - 0.17 11.6 1.4 0.29 10.9 1.0 1.3 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zf-met PF12874.2 KKK16896.1 - 0.61 10.3 5.3 1.8 8.8 0.6 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-BED PF02892.10 KKK16896.1 - 0.9 9.3 9.2 0.34 10.6 1.3 2.3 2 0 0 2 2 2 0 BED zinc finger zf-C2HC_2 PF13913.1 KKK16896.1 - 6.3 6.5 8.4 8.9 6.1 0.7 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type YndJ PF14158.1 KKK16901.1 - 0.1 11.6 1.0 0.14 11.1 0.7 1.1 1 0 0 1 1 1 0 YndJ-like protein CENP-B_dimeris PF09026.5 KKK16902.1 - 0.04 14.1 1.6 0.48 10.7 0.0 2.6 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Zn_clus PF00172.13 KKK16903.1 - 1.9e-08 34.0 6.1 1.9e-08 34.0 4.2 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Hydrophobin PF01185.13 KKK16904.1 - 1.8e-13 50.7 7.8 2.4e-13 50.3 5.4 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Acetyltransf_7 PF13508.1 KKK16905.1 - 4.9e-08 33.0 0.0 5.1e-07 29.7 0.0 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KKK16905.1 - 5.8e-07 29.4 0.0 8.3e-07 28.9 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 KKK16905.1 - 1.1e-06 28.7 0.0 0.00017 21.7 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KKK16905.1 - 8.8e-05 22.3 0.0 0.0086 15.9 0.0 2.4 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KKK16905.1 - 0.00024 20.8 0.0 0.00046 19.8 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.1 KKK16905.1 - 0.00099 18.9 0.0 0.0022 17.8 0.0 1.6 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase DUF3749 PF12568.3 KKK16905.1 - 0.0015 18.0 0.0 0.0052 16.3 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Zip PF02535.17 KKK16906.1 - 7.8e-36 123.6 10.1 7.8e-36 123.6 7.0 1.7 2 0 0 2 2 2 1 ZIP Zinc transporter Herpes_US9 PF06072.6 KKK16907.1 - 0.21 11.4 1.2 0.34 10.7 0.8 1.4 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 p450 PF00067.17 KKK16908.1 - 8.2e-59 199.3 0.0 1.2e-58 198.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_10 PF00331.15 KKK16909.1 - 1.3e-98 329.9 1.4 4.7e-96 321.5 0.9 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 10 DUF4339 PF14237.1 KKK16909.1 - 0.01 15.4 0.1 0.021 14.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4339) SPC25 PF06703.6 KKK16909.1 - 0.093 12.3 0.0 0.2 11.2 0.0 1.6 1 1 1 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) NmrA PF05368.8 KKK16910.1 - 9.4e-37 126.4 0.0 1.1e-36 126.2 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KKK16910.1 - 2.9e-19 69.7 0.0 4.3e-19 69.2 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 KKK16910.1 - 0.0017 17.1 0.1 0.0048 15.6 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 KKK16910.1 - 0.0018 17.7 0.0 0.0076 15.7 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.13 KKK16910.1 - 0.034 14.1 0.0 0.067 13.1 0.0 1.5 1 1 0 1 1 1 0 TrkA-N domain NAD_binding_4 PF07993.7 KKK16910.1 - 0.16 10.8 0.0 2.2 7.1 0.0 2.3 1 1 0 2 2 2 0 Male sterility protein SHR3_chaperone PF08229.6 KKK16911.1 - 8e-76 253.3 0.0 9.2e-76 253.1 0.0 1.0 1 0 0 1 1 1 1 ER membrane protein SH3 Tad PF13400.1 KKK16911.1 - 0.23 11.5 0.3 0.23 11.5 0.2 3.4 4 0 0 4 4 4 0 Putative Flp pilus-assembly TadE/G-like PARG_cat PF05028.9 KKK16912.1 - 5e-28 98.3 0.0 1.4e-27 96.8 0.0 1.6 1 1 0 1 1 1 1 Poly (ADP-ribose) glycohydrolase (PARG) Response_reg PF00072.19 KKK16913.1 - 1.8e-21 76.2 0.1 2.5e-21 75.7 0.1 1.2 1 0 0 1 1 1 1 Response regulator receiver domain Arrestin_N PF00339.24 KKK16914.1 - 1.4e-13 50.8 0.0 9.1e-12 45.0 0.0 2.7 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 KKK16914.1 - 1.2e-08 35.1 0.0 6.9e-05 22.9 0.0 2.6 2 1 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Sugar_tr PF00083.19 KKK16915.1 - 6.8e-87 291.9 24.7 8.2e-87 291.6 17.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KKK16915.1 - 2.6e-27 95.4 20.6 5.9e-27 94.3 12.7 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KKK16915.1 - 0.00011 20.7 29.4 0.0013 17.2 4.6 2.9 2 2 0 2 2 2 2 MFS/sugar transport protein AA_permease_2 PF13520.1 KKK16917.1 - 2.2e-63 214.2 46.1 2.5e-63 214.1 31.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KKK16917.1 - 4.1e-29 101.2 39.4 4.8e-29 101.0 27.3 1.0 1 0 0 1 1 1 1 Amino acid permease His_Phos_2 PF00328.17 KKK16918.1 - 1.9e-36 126.1 0.0 2.1e-36 125.9 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) DDE_Tnp_IS1595 PF12762.2 KKK16919.1 - 0.042 13.6 0.0 0.067 13.0 0.0 1.3 1 0 0 1 1 1 0 ISXO2-like transposase domain bZIP_1 PF00170.16 KKK16920.1 - 4e-08 33.0 9.3 6.3e-08 32.4 6.5 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KKK16920.1 - 7.4e-05 22.4 13.1 0.00012 21.8 8.7 1.5 1 1 1 2 2 2 2 Basic region leucine zipper Macoilin PF09726.4 KKK16920.1 - 0.00069 18.0 0.0 0.00069 18.0 0.0 1.1 1 0 0 1 1 1 1 Transmembrane protein bZIP_Maf PF03131.12 KKK16920.1 - 0.0014 18.8 6.5 0.0022 18.2 4.5 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor FTA4 PF13093.1 KKK16920.1 - 0.006 16.0 0.1 0.0075 15.7 0.1 1.1 1 0 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 CASP_C PF08172.7 KKK16920.1 - 0.0079 15.2 3.0 0.013 14.5 2.1 1.2 1 0 0 1 1 1 1 CASP C terminal DUF2353 PF09789.4 KKK16920.1 - 0.018 14.2 3.0 0.022 14.0 2.1 1.1 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) GAS PF13851.1 KKK16920.1 - 0.027 13.6 2.3 0.039 13.1 1.6 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding TEX13 PF15186.1 KKK16920.1 - 0.031 13.8 2.5 0.048 13.2 1.7 1.2 1 0 0 1 1 1 0 Testis-expressed sequence 13 protein family DivIC PF04977.10 KKK16920.1 - 0.032 13.7 2.0 0.049 13.1 1.4 1.2 1 0 0 1 1 1 0 Septum formation initiator Striatin PF08232.7 KKK16920.1 - 0.064 13.5 1.6 0.064 13.5 1.1 2.0 1 1 1 2 2 2 0 Striatin family DUF2730 PF10805.3 KKK16920.1 - 0.11 12.2 2.2 0.15 11.7 1.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) HALZ PF02183.13 KKK16920.1 - 0.12 12.1 1.6 0.24 11.1 1.1 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper Abhydrolase_3 PF07859.8 KKK16921.1 - 6.6e-45 153.2 3.4 1.1e-43 149.3 2.4 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 KKK16921.1 - 2.7e-09 36.3 1.4 6.8e-09 34.9 1.0 1.6 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 KKK16921.1 - 0.00018 21.2 0.0 0.00025 20.8 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase_phd PF10503.4 KKK16921.1 - 0.023 13.9 0.7 0.12 11.6 0.2 1.9 2 0 0 2 2 2 0 Esterase PHB depolymerase Abhydrolase_2 PF02230.11 KKK16921.1 - 0.037 13.4 0.0 0.076 12.4 0.0 1.5 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Esterase PF00756.15 KKK16921.1 - 0.085 12.2 0.0 0.22 10.9 0.0 1.6 1 1 0 1 1 1 0 Putative esterase Peptidase_S9 PF00326.16 KKK16921.1 - 0.12 11.6 0.0 1.4 8.0 0.0 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family DUF2974 PF11187.3 KKK16921.1 - 0.18 11.1 0.0 0.27 10.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) PHO4 PF01384.15 KKK16934.1 - 9.9e-101 336.6 19.4 1.2e-100 336.3 13.4 1.1 1 0 0 1 1 1 1 Phosphate transporter family MFS_1 PF07690.11 KKK16935.1 - 1.3e-21 76.7 60.1 4.4e-20 71.6 19.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily F-box PF00646.28 KKK16936.1 - 0.0045 16.5 0.6 14 5.4 0.0 3.7 3 0 0 3 3 3 2 F-box domain LRR_4 PF12799.2 KKK16936.1 - 0.021 14.4 0.1 0.58 9.8 0.1 3.2 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) Cytokin_check_N PF10407.4 KKK16936.1 - 0.031 13.8 0.2 0.1 12.2 0.0 1.9 2 0 0 2 2 2 0 Cdc14 phosphatase binding protein N-terminus Glyco_transf_11 PF01531.11 KKK16936.1 - 0.16 10.9 0.0 0.27 10.1 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 11 F-box-like PF12937.2 KKK16936.1 - 8.4 6.2 17.1 85 2.9 0.0 3.4 3 1 0 3 3 3 0 F-box-like ATPase_gene1 PF09527.5 KKK16937.1 - 0.11 12.3 0.2 0.11 12.3 0.1 1.9 2 0 0 2 2 2 0 Putative F0F1-ATPase subunit (ATPase_gene1) DUF1212 PF06738.7 KKK16938.1 - 1.5e-53 181.1 5.3 1.6e-48 164.7 0.1 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF1212) DUF3815 PF12821.2 KKK16938.1 - 4.1e-27 94.6 7.6 4.1e-27 94.6 5.2 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3815) Fungal_trans_2 PF11951.3 KKK16940.1 - 3.7e-10 38.9 0.0 6.9e-10 38.0 0.0 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain TFIIS_C PF01096.13 KKK16941.1 - 2.3 7.9 5.2 0.25 10.9 0.3 1.9 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) Cellulase PF00150.13 KKK16942.1 - 1e-16 61.0 0.3 2.3e-16 59.8 0.2 1.5 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Abhydrolase_6 PF12697.2 KKK16944.1 - 3e-11 43.6 0.1 5.7e-11 42.7 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KKK16944.1 - 1.4e-10 41.0 0.0 3.3e-10 39.9 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF1100 PF06500.6 KKK16944.1 - 4.6e-10 38.6 0.0 6.4e-10 38.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Peptidase_S9 PF00326.16 KKK16944.1 - 1.8e-06 27.3 0.0 4.1e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family BAAT_C PF08840.6 KKK16944.1 - 0.00014 21.6 0.0 0.00066 19.4 0.0 1.9 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S15 PF02129.13 KKK16944.1 - 0.00047 19.6 0.0 0.00082 18.8 0.0 1.4 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) DUF1771 PF08590.5 KKK16944.1 - 0.013 15.5 1.4 0.026 14.5 0.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1771) Esterase PF00756.15 KKK16944.1 - 0.027 13.8 0.1 0.11 11.9 0.0 2.0 1 1 0 1 1 1 0 Putative esterase Abhydrolase_1 PF00561.15 KKK16944.1 - 0.029 13.9 0.3 0.44 10.0 0.0 2.8 2 2 1 3 3 3 0 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 KKK16944.1 - 0.068 12.7 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold DLH PF01738.13 KKK16944.1 - 0.076 12.2 0.0 0.57 9.4 0.0 2.1 1 1 0 1 1 1 0 Dienelactone hydrolase family Esterase_phd PF10503.4 KKK16944.1 - 0.087 12.0 0.1 0.15 11.2 0.1 1.3 1 0 0 1 1 1 0 Esterase PHB depolymerase AA_permease PF00324.16 KKK16945.1 - 1.1e-110 370.2 39.3 1.3e-110 369.9 27.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KKK16945.1 - 2.1e-35 122.1 45.6 2.5e-35 121.8 31.6 1.0 1 0 0 1 1 1 1 Amino acid permease CBM-like PF14683.1 KKK16946.1 - 5.5e-40 136.7 0.0 1.2e-39 135.6 0.0 1.6 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.1 KKK16946.1 - 1.1e-24 86.3 0.7 1.1e-24 86.3 0.5 2.5 3 0 0 3 3 3 1 Polysaccharide lyase family 4, domain II CarboxypepD_reg PF13620.1 KKK16946.1 - 9.3e-10 38.4 3.0 2e-08 34.1 0.5 2.9 3 0 0 3 3 3 1 Carboxypeptidase regulatory-like domain DUF4198 PF10670.4 KKK16946.1 - 0.0041 17.1 0.1 0.025 14.5 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4198) DUF2012 PF09430.5 KKK16946.1 - 0.14 11.9 0.0 0.32 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2012) Cu-oxidase_3 PF07732.10 KKK16947.1 - 3.4e-39 133.2 4.6 7.9e-39 132.0 0.4 3.1 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.17 KKK16947.1 - 5e-33 114.2 0.1 3.8e-32 111.3 0.0 2.1 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 KKK16947.1 - 6.4e-16 58.1 9.0 9.4e-15 54.3 0.1 3.0 2 1 0 2 2 2 2 Multicopper oxidase PAZ PF02170.17 KKK16947.1 - 0.15 11.3 0.0 0.41 9.9 0.0 1.6 2 0 0 2 2 2 0 PAZ domain Glyco_hydro_75 PF07335.6 KKK16948.1 - 4e-48 163.2 0.2 5.1e-48 162.9 0.1 1.1 1 0 0 1 1 1 1 Fungal chitosanase of glycosyl hydrolase group 75 UDPG_MGDP_dh_N PF03721.9 KKK16949.1 - 8.6e-36 123.0 0.0 3.6e-24 85.1 0.0 2.2 1 1 1 2 2 2 2 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh_C PF03720.10 KKK16949.1 - 8.3e-13 48.4 0.0 6.2e-12 45.6 0.0 2.2 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh PF00984.14 KKK16949.1 - 2.2e-09 37.4 0.0 2.5e-08 34.0 0.0 2.5 2 1 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain Ldh_1_N PF00056.18 KKK16949.1 - 0.1 12.4 0.1 17 5.2 0.0 3.2 3 0 0 3 3 3 0 lactate/malate dehydrogenase, NAD binding domain Las1 PF04031.8 KKK16971.1 - 3.8e-46 156.5 0.0 6.3e-46 155.8 0.0 1.3 1 0 0 1 1 1 1 Las1-like Lactamase_B PF00753.22 KKK16971.1 - 4.3e-23 81.9 1.7 2.6e-22 79.4 0.7 2.6 2 1 0 2 2 2 1 Metallo-beta-lactamase superfamily BcrAD_BadFG PF01869.15 KKK16971.1 - 0.024 13.9 0.0 0.042 13.1 0.0 1.3 1 0 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family Peptidase_S26 PF10502.4 KKK16972.1 - 4.2e-05 23.0 0.0 0.0027 17.2 0.0 2.3 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 S-antigen PF05756.6 KKK16973.1 - 0.014 15.3 0.2 0.02 14.8 0.1 1.2 1 0 0 1 1 1 0 S-antigen protein SURF2 PF05477.6 KKK16973.1 - 0.15 11.1 3.3 0.24 10.5 2.3 1.2 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) Glyco_transf_41 PF13844.1 KKK16990.1 - 4.5e-100 334.8 0.0 7.9e-51 172.4 0.0 3.1 1 1 1 2 2 2 2 Glycosyl transferase family 41 TPR_11 PF13414.1 KKK16990.1 - 5.7e-19 67.5 18.6 2.6e-07 30.1 0.2 5.0 5 0 0 5 5 5 3 TPR repeat TPR_1 PF00515.23 KKK16990.1 - 3.1e-18 64.5 10.5 4.9e-05 22.7 0.0 7.0 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_2 PF07719.12 KKK16990.1 - 6.2e-14 50.7 17.8 0.0056 16.4 0.0 6.7 7 0 0 7 7 6 5 Tetratricopeptide repeat TPR_12 PF13424.1 KKK16990.1 - 4.5e-13 48.9 11.5 3.9e-07 29.8 0.6 4.1 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 KKK16990.1 - 4.8e-10 39.1 14.2 0.0071 16.8 0.0 6.1 3 2 2 5 5 5 4 Tetratricopeptide repeat TPR_17 PF13431.1 KKK16990.1 - 5.5e-10 38.6 4.5 0.23 11.7 0.1 5.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 KKK16990.1 - 3.6e-09 37.0 21.1 0.0024 18.4 1.1 5.5 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.1 KKK16990.1 - 1.8e-08 33.5 6.7 0.073 12.8 0.0 6.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.1 KKK16990.1 - 1.8e-06 28.1 8.7 0.0064 16.8 0.1 3.7 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 KKK16990.1 - 2.7e-06 26.7 8.3 0.16 11.8 0.1 5.5 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_10 PF13374.1 KKK16990.1 - 0.00024 20.9 20.9 0.049 13.5 0.1 6.2 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_5 PF12688.2 KKK16990.1 - 0.0044 17.0 1.7 0.048 13.6 0.1 2.9 3 0 0 3 3 3 1 Tetratrico peptide repeat TPR_15 PF13429.1 KKK16990.1 - 0.0058 15.7 0.3 0.41 9.6 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 KKK16990.1 - 0.0077 16.6 6.0 17 6.1 0.0 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_9 PF13371.1 KKK16990.1 - 0.081 12.7 9.0 0.087 12.6 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF2225 PF09986.4 KKK16990.1 - 0.28 10.5 0.0 0.94 8.8 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) BTAD PF03704.12 KKK16990.1 - 0.74 10.1 12.4 2.1 8.6 0.0 4.2 5 0 0 5 5 5 0 Bacterial transcriptional activator domain DUF3638 PF12340.3 KKK16991.1 - 2.5e-97 324.3 0.0 4.4e-97 323.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.3 KKK16991.1 - 2.3e-15 55.4 0.0 6.9e-15 53.8 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3645) DUF2414 PF10309.4 KKK16992.1 - 3.9e-24 84.0 0.0 6.1e-24 83.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2414) DUF3439 PF11921.3 KKK16992.1 - 0.041 13.6 0.5 0.1 12.3 0.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Myb_DNA-binding PF00249.26 KKK16993.1 - 1e-23 83.0 1.3 2.4e-13 49.9 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KKK16993.1 - 4.3e-20 71.5 5.1 4.2e-15 55.5 0.0 2.7 2 1 1 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 KKK16993.1 - 0.023 14.8 1.3 0.052 13.6 0.1 2.2 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain HTH_38 PF13936.1 KKK16993.1 - 0.027 14.0 0.0 0.058 12.9 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain DUF2774 PF11242.3 KKK16993.1 - 0.027 14.4 0.0 0.062 13.2 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2774) HTH_23 PF13384.1 KKK16993.1 - 0.15 11.7 0.1 0.44 10.2 0.0 1.7 2 0 0 2 2 2 0 Homeodomain-like domain FAD_binding_4 PF01565.18 KKK17006.1 - 1.3e-13 50.5 0.1 2.1e-13 49.9 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain T2SE PF00437.15 KKK17007.1 - 0.0017 17.3 0.0 0.0055 15.6 0.0 1.7 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_14 PF13173.1 KKK17007.1 - 0.0019 18.0 0.0 0.004 17.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KKK17007.1 - 0.0035 18.1 0.1 0.015 16.0 0.0 2.1 2 1 0 3 3 3 1 AAA domain AAA_16 PF13191.1 KKK17007.1 - 0.051 13.5 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_10 PF12846.2 KKK17007.1 - 0.12 11.8 0.0 0.55 9.6 0.0 1.9 1 1 0 1 1 1 0 AAA-like domain AAA_18 PF13238.1 KKK17007.1 - 0.15 12.4 0.0 0.65 10.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain Scs3p PF10261.4 KKK17009.1 - 8.8e-62 208.2 6.7 1.1e-61 207.9 4.6 1.1 1 0 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM DUF1614 PF07758.6 KKK17009.1 - 0.063 12.9 0.6 0.48 10.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1614) 2OG-FeII_Oxy_2 PF13532.1 KKK17010.1 - 1.2e-29 103.5 0.0 1.8e-29 102.9 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Peptidase_M35 PF02102.10 KKK17011.1 - 1.4e-58 198.3 8.2 2e-58 197.7 5.7 1.2 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.1 KKK17011.1 - 7.2e-07 29.8 1.6 1.2e-06 29.0 1.1 1.4 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase PhageMin_Tail PF10145.4 KKK17011.1 - 0.00098 18.8 0.8 0.0023 17.6 0.4 1.7 2 0 0 2 2 2 1 Phage-related minor tail protein Zn_clus PF00172.13 KKK17012.1 - 2.7e-07 30.3 10.8 6.3e-07 29.1 7.5 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DIOX_N PF14226.1 KKK17013.1 - 8.6e-28 97.2 0.0 1.4e-27 96.5 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KKK17013.1 - 1.2e-17 63.9 0.0 2.2e-17 63.1 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily FAD_binding_3 PF01494.14 KKK17014.1 - 2.7e-22 79.3 0.0 4.9e-22 78.4 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 KKK17014.1 - 5e-05 23.2 0.0 0.00012 22.0 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KKK17014.1 - 8.3e-05 21.6 0.0 1.3 7.8 0.0 3.1 2 1 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 KKK17014.1 - 0.0013 19.1 0.0 0.23 11.9 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KKK17014.1 - 0.0016 18.5 0.0 0.0052 16.8 0.0 2.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KKK17014.1 - 0.017 13.9 0.0 0.06 12.1 0.0 1.8 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_2 PF07992.9 KKK17014.1 - 0.1 12.4 0.0 0.25 11.1 0.0 1.8 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ADH_zinc_N PF00107.21 KKK17015.1 - 2.5e-11 43.2 0.0 7.2e-11 41.7 0.0 1.9 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KKK17015.1 - 1.9e-05 24.3 0.1 3.7e-05 23.4 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ketoacyl-synt PF00109.21 KKK17016.1 - 1.2e-75 254.3 0.0 2.6e-75 253.1 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 KKK17016.1 - 1.5e-51 174.6 0.6 7.7e-51 172.3 0.0 2.5 2 0 0 2 2 2 1 KR domain PS-DH PF14765.1 KKK17016.1 - 4.2e-47 160.7 0.1 9.4e-47 159.5 0.0 1.7 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.16 KKK17016.1 - 4.3e-46 157.7 0.2 7.7e-46 156.8 0.1 1.3 1 0 0 1 1 1 1 Acyl transferase domain adh_short PF00106.20 KKK17016.1 - 2.5e-43 147.8 5.3 7.4e-43 146.3 0.0 3.4 3 0 0 3 3 3 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 KKK17016.1 - 6.4e-27 93.7 0.0 1.7e-26 92.3 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 KKK17016.1 - 1e-18 67.5 0.0 3.9e-18 65.7 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KKK17016.1 - 1.7e-13 50.6 0.0 3.6e-13 49.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KKK17016.1 - 5.1e-11 42.3 0.0 1.2e-10 41.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KKK17016.1 - 1.1e-10 41.8 0.0 2.7e-10 40.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KKK17016.1 - 1.3e-10 41.8 0.0 6.8e-09 36.2 0.0 3.3 3 0 0 3 3 2 1 Methyltransferase domain Thiolase_N PF00108.18 KKK17016.1 - 1.4e-05 24.2 0.0 2.7e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Ubie_methyltran PF01209.13 KKK17016.1 - 0.00017 20.8 0.0 0.00032 19.8 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family DUF938 PF06080.7 KKK17016.1 - 0.013 15.0 0.0 0.029 13.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_16 PF10294.4 KKK17016.1 - 0.014 14.8 0.0 0.029 13.8 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase DREV PF05219.7 KKK17016.1 - 0.055 12.3 0.0 0.1 11.4 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_PK PF05891.7 KKK17016.1 - 0.35 10.1 0.0 0.95 8.7 0.0 1.6 2 0 0 2 2 2 0 AdoMet dependent proline di-methyltransferase DLH PF01738.13 KKK17017.1 - 4.4e-16 58.8 0.0 1.1e-15 57.5 0.0 1.6 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 KKK17017.1 - 4.6e-06 26.4 0.0 6.1e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family AD PF09793.4 KKK17019.1 - 4.9e-27 93.5 0.0 7.7e-27 92.9 0.0 1.3 1 0 0 1 1 1 1 Anticodon-binding domain 6PGD PF00393.14 KKK17020.1 - 2.4e-134 447.1 0.0 3e-134 446.7 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 KKK17020.1 - 3.2e-52 176.6 0.0 5e-52 176.0 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 KKK17020.1 - 0.0049 16.9 0.0 0.014 15.4 0.0 1.7 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase PGK PF00162.14 KKK17020.1 - 0.21 10.1 0.0 0.32 9.4 0.0 1.2 1 0 0 1 1 1 0 Phosphoglycerate kinase RRM_1 PF00076.17 KKK17021.1 - 2.3e-17 62.3 0.0 3.7e-17 61.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KKK17021.1 - 1.5e-11 44.0 0.0 2.8e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KKK17021.1 - 0.0044 16.8 0.0 0.0073 16.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ABC2_membrane PF01061.19 KKK17022.1 - 1.6e-88 295.3 60.9 1e-48 165.3 17.4 3.4 4 0 0 4 4 4 2 ABC-2 type transporter PDR_CDR PF06422.7 KKK17022.1 - 6.3e-37 125.3 0.5 6.6e-29 99.6 0.0 2.9 2 0 0 2 2 2 2 CDR ABC transporter ABC_tran PF00005.22 KKK17022.1 - 5.6e-35 120.6 0.0 7.6e-17 61.8 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.2 KKK17022.1 - 4.6e-12 45.6 44.1 7.4e-07 28.5 15.2 2.4 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.1 KKK17022.1 - 4.2e-08 33.5 0.1 0.0065 16.4 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 KKK17022.1 - 5.9e-08 32.3 0.0 0.00079 18.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 KKK17022.1 - 3e-07 31.2 0.0 9.1e-05 23.2 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KKK17022.1 - 4.1e-07 30.1 1.0 1.2e-05 25.3 0.1 2.6 2 0 0 2 2 2 1 AAA ATPase domain ABC_trans_N PF14510.1 KKK17022.1 - 1.6e-06 28.0 0.0 5e-06 26.5 0.0 1.9 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_29 PF13555.1 KKK17022.1 - 2.6e-06 26.8 0.1 0.0032 16.9 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 KKK17022.1 - 4.6e-06 26.8 0.0 0.0061 16.6 0.0 3.5 2 1 0 2 2 2 1 AAA domain DUF258 PF03193.11 KKK17022.1 - 8.5e-06 25.0 0.1 2.8e-05 23.3 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function, DUF258 cobW PF02492.14 KKK17022.1 - 9.4e-06 25.1 0.0 0.00025 20.5 0.0 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 KKK17022.1 - 1.5e-05 24.9 0.0 0.0026 17.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 KKK17022.1 - 0.0003 20.3 0.1 0.97 8.8 0.0 2.5 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_18 PF13238.1 KKK17022.1 - 0.00034 20.9 0.0 0.012 15.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 KKK17022.1 - 0.001 19.0 0.2 0.16 11.9 0.1 2.8 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_28 PF13521.1 KKK17022.1 - 0.0012 18.7 0.6 0.0039 17.1 0.1 2.1 2 0 0 2 2 1 1 AAA domain AAA_23 PF13476.1 KKK17022.1 - 0.0017 18.7 0.9 0.021 15.1 0.0 2.5 2 1 0 2 2 2 1 AAA domain NACHT PF05729.7 KKK17022.1 - 0.0019 17.8 0.5 0.056 13.1 0.1 2.6 2 0 0 2 2 2 1 NACHT domain AAA_19 PF13245.1 KKK17022.1 - 0.0022 17.6 0.8 0.17 11.6 0.2 2.6 2 0 0 2 2 2 1 Part of AAA domain AAA_10 PF12846.2 KKK17022.1 - 0.0037 16.7 1.5 0.86 8.9 0.1 2.8 2 1 0 2 2 2 1 AAA-like domain UPF0079 PF02367.12 KKK17022.1 - 0.004 16.7 1.1 0.054 13.1 0.3 2.3 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 SMC_N PF02463.14 KKK17022.1 - 0.0054 15.9 0.1 4.6 6.4 0.0 3.0 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA PF00004.24 KKK17022.1 - 0.015 15.5 0.0 0.56 10.4 0.0 2.9 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 KKK17022.1 - 0.015 14.8 0.5 0.088 12.3 0.1 2.1 2 0 0 2 2 2 0 AAA domain ABC_ATPase PF09818.4 KKK17022.1 - 0.052 12.1 0.7 0.15 10.5 0.3 1.9 2 0 0 2 2 2 0 Predicted ATPase of the ABC class Zeta_toxin PF06414.7 KKK17022.1 - 0.081 12.0 0.2 0.29 10.2 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin T2SE PF00437.15 KKK17022.1 - 0.086 11.7 0.4 1.7 7.4 0.1 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein RNA_helicase PF00910.17 KKK17022.1 - 0.13 12.4 0.1 3.4 7.9 0.0 2.6 2 0 0 2 2 2 0 RNA helicase Dynamin_N PF00350.18 KKK17022.1 - 0.13 12.0 0.2 1.3 8.8 0.1 2.6 3 0 0 3 3 3 0 Dynamin family Miro PF08477.8 KKK17022.1 - 0.15 12.5 0.0 2.5 8.5 0.0 2.5 2 0 0 2 2 2 0 Miro-like protein AAA_15 PF13175.1 KKK17022.1 - 0.24 10.3 0.0 0.6 9.0 0.0 1.6 2 0 0 2 2 1 0 AAA ATPase domain PduV-EutP PF10662.4 KKK17022.1 - 0.3 10.5 0.1 1.7 8.1 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation 2OG-FeII_Oxy_2 PF13532.1 KKK17023.1 - 1.7e-27 96.4 0.0 2.5e-27 95.9 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 KKK17023.1 - 0.041 14.3 0.0 0.097 13.1 0.0 1.6 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Ribophorin_II PF05817.9 KKK17032.1 - 3.9e-21 74.9 0.0 4.7e-21 74.6 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II DPM2 PF07297.7 KKK17032.1 - 0.18 12.0 1.6 0.41 10.9 1.1 1.6 1 0 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) Acyl_transf_3 PF01757.17 KKK17044.1 - 1.4e-24 86.5 23.8 2.4e-24 85.8 16.4 1.4 1 1 0 1 1 1 1 Acyltransferase family TAFII28 PF04719.9 KKK17045.1 - 2.4e-19 68.9 0.0 4.3e-19 68.0 0.0 1.4 1 0 0 1 1 1 1 hTAFII28-like protein conserved region SAM_decarbox PF01536.11 KKK17046.1 - 3.2e-85 285.7 0.0 9.6e-84 280.8 0.0 2.4 1 1 0 1 1 1 1 Adenosylmethionine decarboxylase DUF1546 PF07571.8 KKK17046.1 - 1.2e-34 118.2 0.0 2.4e-34 117.2 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1546) TAF PF02969.12 KKK17046.1 - 7.1e-24 83.5 0.1 2.5e-23 81.8 0.1 2.0 2 0 0 2 2 2 1 TATA box binding protein associated factor (TAF) Histone PF00125.19 KKK17046.1 - 0.00036 20.5 0.2 0.0012 18.9 0.1 1.9 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KKK17046.1 - 0.014 15.4 0.1 0.037 14.0 0.0 1.7 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CRAL_TRIO PF00650.15 KKK17047.1 - 8.8e-16 57.7 0.2 2.8e-15 56.1 0.1 1.7 1 1 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 KKK17047.1 - 0.0032 17.5 0.0 0.007 16.4 0.0 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Aldedh PF00171.17 KKK17048.1 - 1.2e-151 505.2 0.2 1.8e-151 504.6 0.1 1.2 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Gln-synt_C PF00120.19 KKK17048.1 - 1.7e-43 148.6 0.0 3.4e-43 147.6 0.0 1.5 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Amidohydro_2 PF04909.9 KKK17048.1 - 3.1e-33 115.5 0.0 6.5e-33 114.4 0.0 1.5 1 0 0 1 1 1 1 Amidohydrolase DMRL_synthase PF00885.14 KKK17048.1 - 0.069 12.8 0.0 0.7 9.5 0.0 2.4 2 1 1 3 3 3 0 6,7-dimethyl-8-ribityllumazine synthase Ribosomal_60s PF00428.14 KKK17109.1 - 7.5e-06 26.2 0.0 8.7e-06 26.0 0.0 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Fungal_trans PF04082.13 KKK17110.1 - 2.4e-18 65.9 1.4 3.6e-18 65.3 1.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK17110.1 - 6e-09 35.6 10.8 1.2e-08 34.6 7.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Metallophos_2 PF12850.2 KKK17111.1 - 0.062 13.1 0.0 0.067 13.0 0.0 1.3 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain FAD_binding_3 PF01494.14 KKK17112.1 - 1.1e-15 57.5 0.5 1.8e-09 37.1 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 KKK17112.1 - 3.1e-09 36.7 0.8 7.6e-09 35.4 0.5 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KKK17112.1 - 3.1e-07 29.6 2.9 3.1e-07 29.6 2.0 1.9 1 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 KKK17112.1 - 5.6e-06 25.7 0.0 7.9e-06 25.1 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KKK17112.1 - 1.1e-05 25.4 0.2 2.1e-05 24.5 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KKK17112.1 - 4.6e-05 22.4 0.0 6.4e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.19 KKK17112.1 - 0.00012 21.2 0.1 0.0013 17.8 0.1 2.0 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox PF00070.22 KKK17112.1 - 0.00048 20.4 1.3 0.0014 18.9 0.9 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KKK17112.1 - 0.0036 16.2 0.8 0.0057 15.5 0.5 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 KKK17112.1 - 0.0057 16.7 0.0 0.024 14.6 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KKK17112.1 - 0.0098 14.8 0.0 0.015 14.2 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Rossmann-like PF10727.4 KKK17112.1 - 0.014 15.1 0.1 0.026 14.2 0.1 1.4 1 0 0 1 1 1 0 Rossmann-like domain HI0933_like PF03486.9 KKK17112.1 - 0.019 13.4 1.2 0.03 12.8 0.9 1.3 1 0 0 1 1 1 0 HI0933-like protein NAD_Gly3P_dh_N PF01210.18 KKK17112.1 - 0.032 13.9 0.4 0.056 13.1 0.3 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Trp_halogenase PF04820.9 KKK17112.1 - 0.033 12.8 1.0 0.25 9.9 0.6 2.0 2 0 0 2 2 2 0 Tryptophan halogenase AlaDh_PNT_C PF01262.16 KKK17112.1 - 0.047 13.2 0.0 0.088 12.3 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.13 KKK17112.1 - 0.19 11.3 0.6 0.4 10.3 0.4 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_9 PF13454.1 KKK17112.1 - 0.25 11.1 0.9 0.78 9.4 0.5 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding Kelch_5 PF13854.1 KKK17113.1 - 8e-19 67.1 3.9 1.2e-16 60.2 1.0 3.6 4 0 0 4 4 4 1 Kelch motif Kelch_3 PF13415.1 KKK17113.1 - 5.5e-06 26.4 4.5 0.051 13.7 0.0 5.6 5 0 0 5 5 5 1 Galactose oxidase, central domain Kelch_1 PF01344.20 KKK17113.1 - 5.9e-06 25.7 0.7 0.018 14.5 0.1 3.4 3 0 0 3 3 3 2 Kelch motif Kelch_6 PF13964.1 KKK17113.1 - 8.2e-06 25.7 6.4 0.02 15.0 0.3 4.8 5 0 0 5 5 5 2 Kelch motif Kelch_4 PF13418.1 KKK17113.1 - 5.6e-05 22.8 8.2 0.059 13.1 0.1 5.8 5 2 1 6 6 6 1 Galactose oxidase, central domain MLANA PF14991.1 KKK17113.1 - 0.037 14.0 0.0 0.092 12.7 0.0 1.6 1 0 0 1 1 1 0 Protein melan-A COPIIcoated_ERV PF07970.7 KKK17116.1 - 3.3e-32 111.9 0.1 8.3e-31 107.3 0.1 2.2 1 1 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 KKK17116.1 - 5.1e-24 84.0 0.0 9.1e-24 83.2 0.0 1.4 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Pkinase PF00069.20 KKK17117.1 - 1.4e-58 198.0 0.0 2.1e-58 197.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK17117.1 - 2.7e-20 72.5 0.0 4.6e-20 71.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Phage_GP20 PF06810.6 KKK17117.1 - 0.077 12.4 0.0 0.99 8.8 0.0 2.2 2 0 0 2 2 2 0 Phage minor structural protein GP20 APH PF01636.18 KKK17117.1 - 0.093 12.4 0.0 0.56 9.8 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family CCDC92 PF14916.1 KKK17118.1 - 0.11 12.1 0.0 0.11 12.1 0.0 4.6 4 1 1 5 5 5 0 Coiled-coil domain of unknown function Baculo_PEP_C PF04513.7 KKK17118.1 - 2.2 8.1 10.3 8.9 6.1 2.0 2.6 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Dak2 PF02734.12 KKK17118.1 - 6.5 6.3 10.1 0.84 9.2 2.8 2.4 2 0 0 2 2 2 0 DAK2 domain TPR_MLP1_2 PF07926.7 KKK17118.1 - 6.8 6.4 53.8 0.11 12.2 6.1 4.4 4 0 0 4 4 4 0 TPR/MLP1/MLP2-like protein Maf1 PF09174.5 KKK17120.1 - 9.5e-66 221.0 0.1 1.6e-65 220.3 0.0 1.4 1 0 0 1 1 1 1 Maf1 regulator Clat_adaptor_s PF01217.15 KKK17120.1 - 4.2e-32 110.8 1.1 6.3e-32 110.2 0.7 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain ABC_tran PF00005.22 KKK17121.1 - 2.9e-46 157.1 0.0 5.2e-28 98.0 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 KKK17121.1 - 7.9e-34 117.3 18.6 1.4e-17 64.0 5.3 3.5 3 0 0 3 3 3 3 ABC transporter transmembrane region SMC_N PF02463.14 KKK17121.1 - 4.5e-12 45.6 4.1 0.00016 20.9 0.1 4.2 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KKK17121.1 - 1.9e-10 41.2 0.0 0.0072 16.3 0.0 4.4 3 1 0 3 3 3 2 AAA domain AAA_25 PF13481.1 KKK17121.1 - 1.5e-07 31.0 0.1 0.0056 16.1 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_23 PF13476.1 KKK17121.1 - 6.2e-07 29.9 2.9 0.00023 21.5 0.2 2.5 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 KKK17121.1 - 3.2e-06 27.3 3.4 0.015 15.4 0.0 3.4 3 1 0 3 3 2 2 AAA domain AAA_16 PF13191.1 KKK17121.1 - 1.1e-05 25.5 9.8 0.0036 17.3 0.4 4.1 3 2 0 3 3 3 2 AAA ATPase domain AAA_29 PF13555.1 KKK17121.1 - 2.1e-05 23.9 4.9 0.0006 19.2 0.2 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 KKK17121.1 - 6.2e-05 22.9 0.0 0.057 13.3 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase T2SE PF00437.15 KKK17121.1 - 8.7e-05 21.5 1.6 0.13 11.1 0.0 2.5 2 0 0 2 2 2 2 Type II/IV secretion system protein DUF258 PF03193.11 KKK17121.1 - 0.00021 20.5 0.2 0.62 9.2 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 NACHT PF05729.7 KKK17121.1 - 0.00043 19.9 0.1 0.7 9.5 0.0 2.8 2 0 0 2 2 2 2 NACHT domain Miro PF08477.8 KKK17121.1 - 0.00044 20.7 0.0 0.044 14.2 0.0 2.5 2 0 0 2 2 2 1 Miro-like protein AAA PF00004.24 KKK17121.1 - 0.00097 19.3 0.0 0.98 9.6 0.0 3.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 KKK17121.1 - 0.005 16.4 2.5 3 7.3 0.0 3.2 3 0 0 3 3 3 1 AAA domain SbcCD_C PF13558.1 KKK17121.1 - 0.0082 16.0 0.0 7.7 6.5 0.0 2.8 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit cobW PF02492.14 KKK17121.1 - 0.009 15.4 2.1 0.7 9.3 0.2 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.1 KKK17121.1 - 0.015 15.6 0.0 5.8 7.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 KKK17121.1 - 0.018 14.7 0.3 0.13 11.8 0.0 2.3 2 0 0 2 2 2 0 Archaeal ATPase AAA_11 PF13086.1 KKK17121.1 - 0.028 13.9 0.0 0.83 9.1 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_17 PF13207.1 KKK17121.1 - 0.033 15.0 0.0 3.9 8.3 0.0 2.9 2 0 0 2 2 2 0 AAA domain AAA_13 PF13166.1 KKK17121.1 - 0.051 12.0 1.6 10 4.4 0.0 3.4 4 0 0 4 4 4 0 AAA domain DUF2075 PF09848.4 KKK17121.1 - 0.057 12.3 0.1 2.2 7.1 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) RNA_helicase PF00910.17 KKK17121.1 - 0.062 13.4 0.0 15 5.8 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_10 PF12846.2 KKK17121.1 - 0.088 12.2 2.4 1.4 8.2 0.1 3.1 3 0 0 3 3 3 0 AAA-like domain MobB PF03205.9 KKK17121.1 - 0.09 12.4 0.8 1.6 8.4 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Mg_chelatase PF01078.16 KKK17121.1 - 0.097 11.8 0.0 1.6 7.8 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Zot PF05707.7 KKK17121.1 - 0.11 11.9 0.1 1.4 8.3 0.0 2.6 3 0 0 3 3 2 0 Zonular occludens toxin (Zot) AAA_24 PF13479.1 KKK17121.1 - 0.13 11.8 2.2 2.4 7.6 0.3 2.5 2 0 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.4 KKK17121.1 - 0.23 10.0 2.3 7.5 5.0 0.1 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain FtsK_SpoIIIE PF01580.13 KKK17121.1 - 0.26 10.7 1.7 4.3 6.7 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family KaiC PF06745.8 KKK17121.1 - 0.29 10.1 0.8 4.7 6.2 0.0 2.5 2 0 0 2 2 2 0 KaiC DUF87 PF01935.12 KKK17121.1 - 0.3 10.8 5.4 0.047 13.5 0.4 2.0 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_15 PF13175.1 KKK17121.1 - 0.37 9.7 0.1 0.96 8.4 0.0 1.7 2 0 0 2 2 1 0 AAA ATPase domain AAA_19 PF13245.1 KKK17121.1 - 0.41 10.4 5.5 3.3 7.5 0.1 3.2 3 0 0 3 3 3 0 Part of AAA domain AAA_5 PF07728.9 KKK17121.1 - 0.44 10.2 1.5 9.4 5.9 0.1 2.7 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) PduV-EutP PF10662.4 KKK17121.1 - 0.58 9.6 2.9 5.1 6.5 0.2 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ABC_ATPase PF09818.4 KKK17121.1 - 0.66 8.4 2.7 0.56 8.7 0.1 2.0 2 0 0 2 2 2 0 Predicted ATPase of the ABC class Pex24p PF06398.6 KKK17122.1 - 2.7e-62 210.6 0.0 3.2e-62 210.4 0.0 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin DUF4568 PF15132.1 KKK17122.1 - 0.038 13.1 0.4 0.065 12.4 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4568) Pkinase PF00069.20 KKK17126.1 - 1.6e-69 233.9 0.1 3e-69 233.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK17126.1 - 2.6e-52 177.4 0.1 4.5e-52 176.6 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 KKK17126.1 - 4.3e-23 81.5 0.1 1.1e-21 76.9 0.0 2.8 2 0 0 2 2 2 1 P21-Rho-binding domain PH_11 PF15413.1 KKK17126.1 - 2.6e-20 72.7 0.1 5e-20 71.8 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 KKK17126.1 - 1.6e-09 37.8 0.0 3.3e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.1 KKK17126.1 - 4.5e-07 29.1 0.0 9.1e-07 28.1 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KKK17126.1 - 0.012 15.3 0.2 0.012 15.3 0.1 2.4 2 1 0 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 KKK17126.1 - 0.018 13.8 0.1 0.034 12.9 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 NAD_kinase PF01513.16 KKK17127.1 - 1.8e-45 154.9 0.0 5.8e-45 153.2 0.0 1.7 1 1 0 1 1 1 1 ATP-NAD kinase TPR_2 PF07719.12 KKK17128.1 - 7.3e-28 94.2 25.0 0.00063 19.4 0.0 11.8 11 0 0 11 11 11 8 Tetratricopeptide repeat TPR_11 PF13414.1 KKK17128.1 - 2.9e-27 94.1 27.6 2.6e-06 27.0 0.1 10.2 9 1 2 11 11 11 7 TPR repeat TPR_1 PF00515.23 KKK17128.1 - 3.1e-25 86.6 17.6 0.0001 21.7 0.0 10.5 10 0 0 10 10 10 6 Tetratricopeptide repeat Acyltransferase PF01553.16 KKK17128.1 - 4.1e-25 87.7 0.0 8.2e-25 86.7 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase TPR_8 PF13181.1 KKK17128.1 - 1.5e-21 74.5 21.3 0.00021 20.8 0.0 11.5 11 0 0 11 11 11 5 Tetratricopeptide repeat TPR_14 PF13428.1 KKK17128.1 - 6.8e-19 66.6 28.8 0.0084 16.6 0.1 11.7 11 1 1 12 12 11 5 Tetratricopeptide repeat TPR_19 PF14559.1 KKK17128.1 - 4.5e-18 65.3 18.6 0.0012 19.1 0.0 8.0 6 1 1 7 7 7 5 Tetratricopeptide repeat TPR_12 PF13424.1 KKK17128.1 - 2.9e-16 59.1 30.6 3.1e-05 23.8 1.1 9.8 8 2 2 10 10 10 5 Tetratricopeptide repeat TPR_16 PF13432.1 KKK17128.1 - 1.9e-11 44.3 34.6 0.0021 18.6 0.0 10.8 10 2 2 12 12 11 4 Tetratricopeptide repeat TPR_17 PF13431.1 KKK17128.1 - 2.7e-09 36.4 7.9 0.64 10.3 0.0 8.9 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_6 PF13174.1 KKK17128.1 - 8.9e-08 32.1 27.5 0.49 10.9 0.1 11.5 12 0 0 12 12 12 3 Tetratricopeptide repeat Apc3 PF12895.2 KKK17128.1 - 1.7e-06 28.0 10.9 0.047 13.8 0.1 7.1 7 0 0 7 7 7 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 KKK17128.1 - 5.1e-05 22.7 30.9 0.00054 19.5 0.3 9.7 11 0 0 11 11 10 2 Tetratricopeptide repeat TPR_10 PF13374.1 KKK17128.1 - 0.047 13.6 14.5 0.96 9.4 0.1 6.2 5 0 0 5 5 5 0 Tetratricopeptide repeat Pkinase PF00069.20 KKK17129.1 - 1.6e-75 253.6 0.0 2.4e-75 253.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK17129.1 - 3.4e-39 134.4 0.1 1e-38 132.9 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.14 KKK17129.1 - 3.6e-17 61.5 0.3 6.1e-17 60.7 0.2 1.4 1 0 0 1 1 1 1 Kinase associated domain 1 Kinase-like PF14531.1 KKK17129.1 - 5.2e-05 22.3 0.0 0.00013 21.0 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 KKK17129.1 - 6.9e-05 22.0 0.0 0.00014 21.0 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 KKK17129.1 - 0.001 18.4 0.0 0.0022 17.3 0.0 1.5 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL APH PF01636.18 KKK17129.1 - 0.0089 15.7 0.0 0.042 13.5 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family ubiquitin PF00240.18 KKK17130.1 - 3.3e-06 26.3 0.0 5.4e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.4 KKK17130.1 - 0.088 13.0 0.1 0.49 10.6 0.0 2.0 1 1 1 2 2 2 0 DUF2407 ubiquitin-like domain DUF1604 PF07713.8 KKK17131.1 - 4.6e-41 138.4 2.1 3.1e-40 135.8 1.0 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1604) G-patch PF01585.18 KKK17131.1 - 7.2e-08 32.0 1.4 2.1e-07 30.6 1.0 1.8 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 KKK17131.1 - 0.029 14.2 1.4 0.1 12.4 0.4 2.4 1 1 1 2 2 2 0 DExH-box splicing factor binding site Pkinase PF00069.20 KKK17132.1 - 9.8e-66 221.5 0.0 1.8e-65 220.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK17132.1 - 2.6e-35 121.7 0.0 1.3e-33 116.2 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KKK17132.1 - 1.4e-07 30.7 0.1 6e-06 25.4 0.1 2.3 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 KKK17132.1 - 0.0037 17.0 0.0 0.009 15.7 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 KKK17132.1 - 0.017 13.9 0.0 0.032 13.0 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Ammonium_transp PF00909.16 KKK17133.1 - 8e-120 399.9 30.4 9.2e-120 399.7 21.1 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Transgly_assoc PF04226.8 KKK17133.1 - 0.13 12.4 0.2 0.13 12.4 0.2 5.6 6 0 0 6 6 6 0 Transglycosylase associated protein Tubulin PF00091.20 KKK17134.1 - 1.5e-69 234.1 0.0 2.5e-69 233.4 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 KKK17134.1 - 2.7e-50 169.6 0.1 4.6e-50 168.8 0.1 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 KKK17134.1 - 1.6e-05 24.9 0.0 3.8e-05 23.7 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 KKK17134.1 - 0.0048 16.3 0.0 0.0086 15.5 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain RRM_1 PF00076.17 KKK17135.1 - 7.8e-12 44.6 0.1 6.7e-05 22.4 0.0 3.1 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KKK17135.1 - 8.8e-09 35.2 0.1 0.0014 18.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KKK17135.1 - 5.6e-08 32.5 0.0 0.00011 21.9 0.0 2.7 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4651 PF15513.1 KKK17135.1 - 0.059 12.8 0.1 6.1 6.3 0.0 3.0 3 1 0 3 3 3 0 Domain of unknown function (DUF4651) DAGK_cat PF00781.19 KKK17136.1 - 8e-25 86.7 0.0 1.3e-24 86.0 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Adaptin_N PF01602.15 KKK17137.1 - 4e-95 319.1 9.1 6.3e-95 318.4 6.3 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.1 KKK17137.1 - 3.7e-62 207.7 0.0 1.1e-61 206.2 0.0 1.8 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.7 KKK17137.1 - 1.4e-61 206.2 0.9 3.2e-61 205.1 0.6 1.6 1 0 0 1 1 1 1 Coatomer beta C-terminal region HEAT_2 PF13646.1 KKK17137.1 - 1.9e-11 44.1 8.5 3.1e-07 30.5 0.0 4.6 2 1 1 4 4 4 2 HEAT repeats Cnd1 PF12717.2 KKK17137.1 - 1.9e-06 27.8 3.1 0.023 14.5 0.0 3.5 2 1 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.1 KKK17137.1 - 0.00054 20.3 0.9 0.11 12.9 0.0 4.3 2 1 1 3 3 3 2 HEAT-like repeat HEAT PF02985.17 KKK17137.1 - 0.0014 18.5 1.4 0.44 10.7 0.0 4.0 4 0 0 4 4 4 1 HEAT repeat AP4E_app_platf PF14807.1 KKK17137.1 - 0.024 14.8 0.1 0.11 12.7 0.0 2.2 1 0 0 1 1 1 0 Adaptin AP4 complex epsilon appendage platform Mago_nashi PF02792.9 KKK17138.1 - 4.7e-76 253.3 0.3 5.9e-76 252.9 0.2 1.1 1 0 0 1 1 1 1 Mago nashi protein Vac_ImportDeg PF09783.4 KKK17139.1 - 3.1e-71 238.5 1.1 4e-71 238.1 0.8 1.1 1 0 0 1 1 1 1 Vacuolar import and degradation protein ABC2_membrane PF01061.19 KKK17140.1 - 2.8e-94 314.1 53.7 5.7e-48 162.8 14.5 2.5 2 0 0 2 2 2 2 ABC-2 type transporter PDR_CDR PF06422.7 KKK17140.1 - 5.9e-39 131.8 4.7 1.7e-32 111.1 0.0 3.6 3 0 0 3 3 3 2 CDR ABC transporter ABC_tran PF00005.22 KKK17140.1 - 4.7e-36 124.1 0.1 1e-17 64.7 0.0 3.0 3 0 0 3 3 3 2 ABC transporter ABC_trans_N PF14510.1 KKK17140.1 - 4.3e-20 71.5 0.1 1.3e-19 70.0 0.0 1.9 2 0 0 2 2 1 1 ABC-transporter extracellular N-terminal ABC2_membrane_3 PF12698.2 KKK17140.1 - 4.8e-10 39.0 45.3 7.3e-06 25.2 13.1 2.6 2 1 1 3 3 3 2 ABC-2 family transporter protein AAA_25 PF13481.1 KKK17140.1 - 7.4e-09 35.2 0.0 0.00011 21.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 KKK17140.1 - 5.5e-05 23.9 0.0 0.075 13.8 0.0 2.9 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 KKK17140.1 - 6e-05 22.2 0.0 0.0041 16.3 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_33 PF13671.1 KKK17140.1 - 7.3e-05 22.6 0.8 0.14 11.9 0.0 3.0 3 0 0 3 3 2 2 AAA domain cobW PF02492.14 KKK17140.1 - 0.00019 20.9 1.3 0.0023 17.4 0.1 2.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.1 KKK17140.1 - 0.00034 20.6 0.1 0.028 14.4 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.1 KKK17140.1 - 0.00046 20.5 0.0 0.026 14.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 KKK17140.1 - 0.0033 17.5 0.6 0.59 10.2 0.1 2.9 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.1 KKK17140.1 - 0.0043 16.5 3.2 0.043 13.3 0.2 3.0 3 0 0 3 3 3 1 P-loop containing region of AAA domain NACHT PF05729.7 KKK17140.1 - 0.0086 15.7 2.2 2.7 7.6 0.1 2.8 3 0 0 3 3 3 2 NACHT domain RNA_helicase PF00910.17 KKK17140.1 - 0.014 15.5 0.2 3.6 7.8 0.0 2.7 2 0 0 2 2 2 0 RNA helicase SMC_N PF02463.14 KKK17140.1 - 0.016 14.4 0.1 1.1 8.4 0.0 3.2 3 1 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KKK17140.1 - 0.029 14.3 0.0 0.51 10.2 0.0 2.9 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 KKK17140.1 - 0.034 13.8 0.2 2.6 7.8 0.1 2.6 2 0 0 2 2 2 0 Part of AAA domain UPF0079 PF02367.12 KKK17140.1 - 0.053 13.1 0.8 0.59 9.7 0.1 2.2 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Miro PF08477.8 KKK17140.1 - 0.11 12.9 0.2 15 6.1 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein AAA PF00004.24 KKK17140.1 - 0.13 12.4 0.1 12 6.1 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.18 KKK17140.1 - 0.14 12.1 0.0 19 5.2 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_30 PF13604.1 KKK17140.1 - 0.16 11.5 0.1 1.3 8.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 KKK17140.1 - 0.36 11.1 0.3 3.8 7.7 0.1 2.3 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 KKK17140.1 - 3 7.2 4.1 13 5.1 0.1 2.7 3 0 0 3 3 3 0 AAA-like domain PDR_assoc PF08370.6 KKK17140.1 - 6.7 6.2 9.1 0.35 10.4 0.1 3.3 4 0 0 4 4 3 0 Plant PDR ABC transporter associated Nop52 PF05997.7 KKK17141.1 - 8.3e-46 156.1 0.1 6.6e-37 127.0 0.1 2.1 2 0 0 2 2 2 2 Nucleolar protein,Nop52 RNA_pol_Rpc82 PF05645.8 KKK17141.1 - 0.012 15.1 0.1 0.022 14.3 0.1 1.3 1 0 0 1 1 1 0 RNA polymerase III subunit RPC82 DUF2956 PF11169.3 KKK17141.1 - 0.05 13.5 4.4 0.12 12.3 3.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2956) NARP1 PF12569.3 KKK17141.1 - 0.053 12.2 3.2 0.079 11.6 2.2 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF3527 PF12043.3 KKK17141.1 - 0.058 12.9 1.3 0.3 10.5 0.9 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3527) FancD2 PF14631.1 KKK17141.1 - 0.099 9.7 0.2 0.13 9.3 0.1 1.1 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease HTH_IclR PF09339.5 KKK17141.1 - 0.1 12.2 2.0 0.18 11.3 0.1 2.4 3 1 0 3 3 3 0 IclR helix-turn-helix domain NOT2_3_5 PF04153.13 KKK17141.1 - 0.2 11.5 0.0 0.2 11.5 0.0 2.0 2 0 0 2 2 2 0 NOT2 / NOT3 / NOT5 family FLO_LFY PF01698.11 KKK17141.1 - 2.2 7.0 7.2 3.9 6.2 5.0 1.3 1 0 0 1 1 1 0 Floricaula / Leafy protein Transp_cyt_pur PF02133.10 KKK17142.1 - 3.9e-14 52.0 36.5 7.9e-14 51.0 25.3 1.5 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin AAA PF00004.24 KKK17143.1 - 1.3e-37 128.9 0.0 1.9e-37 128.3 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KKK17143.1 - 8.3e-06 25.9 0.2 0.00011 22.3 0.1 2.5 1 1 0 1 1 1 1 AAA domain Vps4_C PF09336.5 KKK17143.1 - 2.2e-05 24.2 0.0 0.0002 21.1 0.0 2.6 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_2 PF07724.9 KKK17143.1 - 3.9e-05 23.6 0.0 6.5e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 KKK17143.1 - 6e-05 22.1 0.0 0.0001 21.4 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 KKK17143.1 - 0.00083 19.0 0.0 0.0022 17.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 KKK17143.1 - 0.0018 17.7 0.0 0.003 16.9 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.1 KKK17143.1 - 0.0018 18.1 0.0 0.0039 17.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 KKK17143.1 - 0.0024 16.6 0.0 0.0036 16.0 0.0 1.2 1 0 0 1 1 1 1 TIP49 C-terminus Mg_chelatase PF01078.16 KKK17143.1 - 0.0038 16.4 0.1 0.0078 15.3 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 KKK17143.1 - 0.0045 16.3 0.2 0.12 11.7 0.1 2.5 1 1 1 2 2 2 1 AAA domain AAA_19 PF13245.1 KKK17143.1 - 0.008 15.9 0.0 0.027 14.2 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 KKK17143.1 - 0.0082 16.1 0.2 0.0082 16.1 0.1 3.0 4 1 0 4 4 3 1 AAA ATPase domain DUF815 PF05673.8 KKK17143.1 - 0.011 14.6 0.0 0.018 13.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_24 PF13479.1 KKK17143.1 - 0.014 14.9 0.0 0.025 14.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 KKK17143.1 - 0.031 14.2 0.4 0.12 12.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 KKK17143.1 - 0.032 15.0 0.6 0.097 13.4 0.0 2.2 2 1 0 2 2 1 0 AAA domain Sigma54_activat PF00158.21 KKK17143.1 - 0.032 13.6 0.0 0.35 10.3 0.0 2.5 2 1 0 2 2 2 0 Sigma-54 interaction domain AAA_14 PF13173.1 KKK17143.1 - 0.074 12.9 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 KKK17143.1 - 0.082 12.5 0.0 0.24 11.0 0.0 1.8 1 1 0 1 1 1 0 NACHT domain Arch_ATPase PF01637.13 KKK17143.1 - 0.088 12.4 0.0 1.3 8.7 0.0 2.3 1 1 0 1 1 1 0 Archaeal ATPase Guanylate_kin PF00625.16 KKK17143.1 - 0.1 12.0 0.0 0.2 11.0 0.0 1.5 1 0 0 1 1 1 0 Guanylate kinase PhoH PF02562.11 KKK17143.1 - 0.15 11.2 0.1 0.29 10.3 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein ENTH PF01417.15 KKK17144.1 - 9.1e-44 148.3 0.0 1.6e-43 147.5 0.0 1.4 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.11 KKK17144.1 - 0.0085 14.8 0.0 0.014 14.1 0.0 1.3 1 0 0 1 1 1 1 ANTH domain DUF4264 PF14084.1 KKK17144.1 - 0.038 13.3 0.0 0.066 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4264) UIM PF02809.15 KKK17144.1 - 0.055 13.0 5.2 0.074 12.6 0.9 2.6 2 0 0 2 2 2 0 Ubiquitin interaction motif Mito_carr PF00153.22 KKK17145.1 - 3.5e-69 228.5 6.3 1.5e-24 85.5 0.1 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein O-antigen_lig PF13425.1 KKK17145.1 - 0.046 13.7 0.1 0.22 11.4 0.0 1.9 2 0 0 2 2 2 0 O-antigen ligase like membrane protein RmlD_sub_bind PF04321.12 KKK17154.1 - 1.5e-54 184.8 0.0 2e-54 184.4 0.0 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.16 KKK17154.1 - 4.2e-21 75.4 0.0 6.6e-21 74.8 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 KKK17154.1 - 6.1e-12 44.9 0.2 3.9e-10 39.0 0.0 2.1 2 0 0 2 2 2 1 Male sterility protein Polysacc_synt_2 PF02719.10 KKK17154.1 - 2.8e-09 36.2 0.2 2.6e-07 29.8 0.0 2.7 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 KKK17154.1 - 2.9e-09 36.0 0.0 1.6e-08 33.6 0.0 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 KKK17154.1 - 3.3e-05 23.9 0.0 5.3e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 KKK17154.1 - 0.00017 21.5 0.3 0.042 13.7 0.1 2.7 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KKK17154.1 - 0.0044 16.6 0.2 2.4 7.7 0.0 2.9 3 0 0 3 3 3 2 KR domain RA PF00788.18 KKK17155.1 - 0.096 13.1 0.0 2 8.9 0.0 2.4 2 0 0 2 2 2 0 Ras association (RalGDS/AF-6) domain PH PF00169.24 KKK17155.1 - 0.14 12.4 1.3 0.3 11.3 0.9 1.5 1 0 0 1 1 1 0 PH domain Gti1_Pac2 PF09729.4 KKK17155.1 - 0.19 11.5 0.0 0.19 11.5 0.0 2.8 3 1 0 3 3 3 0 Gti1/Pac2 family Pkinase PF00069.20 KKK17156.1 - 6.7e-22 77.8 0.0 8.6e-22 77.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK17156.1 - 1.1e-05 24.6 0.0 2.3e-05 23.6 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase FAD-oxidase_C PF02913.14 KKK17157.1 - 1.4e-58 198.1 0.0 1.9e-58 197.7 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 KKK17157.1 - 2.5e-37 127.4 0.5 4.3e-37 126.6 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain Tmemb_14 PF03647.8 KKK17160.1 - 4.7e-23 81.4 9.6 6e-23 81.0 6.6 1.1 1 0 0 1 1 1 1 Transmembrane proteins 14C MFS_1 PF07690.11 KKK17161.1 - 1.8e-30 105.8 36.0 1.1e-29 103.3 10.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KKK17161.1 - 5.7e-08 31.7 6.9 5.7e-08 31.7 4.8 3.3 2 2 1 3 3 3 1 Sugar (and other) transporter SurE PF01975.12 KKK17162.1 - 2.1e-43 147.9 0.0 2.8e-43 147.5 0.0 1.2 1 0 0 1 1 1 1 Survival protein SurE Glyco_transf_28 PF03033.15 KKK17162.1 - 0.058 13.1 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Glycosyltransferase family 28 N-terminal domain Zn_clus PF00172.13 KKK17163.1 - 0.0015 18.4 10.2 0.003 17.4 7.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_60s PF00428.14 KKK17164.1 - 0.014 15.7 4.0 0.014 15.7 2.8 2.9 3 0 0 3 3 3 0 60s Acidic ribosomal protein PPR_3 PF13812.1 KKK17165.1 - 2.4e-20 71.0 12.4 0.013 15.7 0.0 11.6 13 0 0 13 13 13 5 Pentatricopeptide repeat domain PPR_2 PF13041.1 KKK17165.1 - 4e-19 68.3 4.7 6.7e-08 32.3 0.2 7.3 8 1 1 9 9 9 4 PPR repeat family PPR PF01535.15 KKK17165.1 - 1.5e-13 49.7 4.9 0.0092 15.8 0.2 8.9 9 0 0 9 9 9 3 PPR repeat TPR_14 PF13428.1 KKK17165.1 - 9.2e-06 25.8 7.0 8.6 7.3 0.0 8.0 8 1 1 9 9 9 2 Tetratricopeptide repeat PPR_1 PF12854.2 KKK17165.1 - 2.6e-05 23.6 0.2 3.2 7.3 0.0 4.9 4 0 0 4 4 4 1 PPR repeat MCM PF00493.18 KKK17166.1 - 5.6e-128 426.3 0.2 8.5e-128 425.8 0.1 1.3 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 KKK17166.1 - 8.6e-18 64.9 0.0 2.2e-17 63.6 0.0 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 KKK17166.1 - 3.9e-06 26.1 0.0 4.2e-05 22.7 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 KKK17166.1 - 0.0069 15.9 0.0 0.015 14.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Spo7 PF03907.8 KKK17167.1 - 1.1e-64 217.8 0.0 1.8e-64 217.2 0.0 1.3 1 0 0 1 1 1 1 Spo7-like protein Abhydrolase_6 PF12697.2 KKK17168.1 - 3.3e-27 95.8 0.5 7e-27 94.7 0.3 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KKK17168.1 - 8.9e-16 58.1 0.0 1.1e-14 54.5 0.0 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KKK17168.1 - 3.8e-12 46.1 0.0 6.1e-11 42.2 0.0 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF915 PF06028.6 KKK17168.1 - 2.6e-06 26.6 0.0 4.5e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Esterase PF00756.15 KKK17168.1 - 6.9e-06 25.6 0.0 1.6e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Putative esterase PGAP1 PF07819.8 KKK17168.1 - 0.0025 17.4 0.0 0.05 13.1 0.0 2.2 2 0 0 2 2 2 1 PGAP1-like protein Abhydrolase_3 PF07859.8 KKK17168.1 - 0.0071 15.9 0.1 0.018 14.6 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Chlorophyllase2 PF12740.2 KKK17168.1 - 0.0087 14.9 0.0 0.013 14.3 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_2 PF02230.11 KKK17168.1 - 0.013 14.9 0.0 2.2 7.6 0.0 2.4 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Thioesterase PF00975.15 KKK17168.1 - 0.018 15.2 0.2 0.08 13.1 0.1 2.0 1 1 0 1 1 1 0 Thioesterase domain DUF2305 PF10230.4 KKK17168.1 - 0.045 13.1 0.0 0.072 12.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Lipase_3 PF01764.20 KKK17168.1 - 0.049 13.2 0.0 0.15 11.6 0.0 1.7 2 0 0 2 2 2 0 Lipase (class 3) Hydrolase_4 PF12146.3 KKK17168.1 - 0.068 13.0 0.0 0.24 11.2 0.0 1.9 2 0 0 2 2 2 0 Putative lysophospholipase TatD_DNase PF01026.16 KKK17170.1 - 4.7e-33 114.4 0.0 1e-32 113.3 0.0 1.5 1 1 0 1 1 1 1 TatD related DNase Fungal_trans PF04082.13 KKK17171.1 - 7.2e-21 74.2 0.1 3.3e-20 72.0 0.0 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK17171.1 - 5.3e-10 39.0 10.2 8.4e-10 38.4 7.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NRDE-2 PF08424.5 KKK17171.1 - 3.1 6.6 9.7 0.14 11.0 2.3 2.0 2 1 0 2 2 2 0 NRDE-2, necessary for RNA interference CBFD_NFYB_HMF PF00808.18 KKK17172.1 - 2.9e-29 100.8 0.9 4.1e-29 100.4 0.6 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 KKK17172.1 - 1.1e-06 28.6 0.1 1.8e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.11 KKK17172.1 - 0.00075 19.2 0.0 0.0011 18.7 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Bromo_TP PF07524.8 KKK17172.1 - 0.0014 18.3 0.0 0.0025 17.4 0.0 1.4 1 0 0 1 1 1 1 Bromodomain associated TFIID_20kDa PF03847.8 KKK17172.1 - 0.049 13.9 0.0 0.091 13.0 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A Gly-zipper_OmpA PF13436.1 KKK17172.1 - 7.4 6.2 16.7 0.1 12.2 4.6 2.5 3 0 0 3 3 3 0 Glycine-zipper containing OmpA-like membrane domain RTC4 PF14474.1 KKK17173.1 - 9.5e-38 128.9 0.0 1.9e-37 127.9 0.0 1.5 1 0 0 1 1 1 1 RTC4-like domain zf-MIZ PF02891.15 KKK17173.1 - 0.15 11.6 1.1 0.26 10.8 0.7 1.4 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger DUF726 PF05277.7 KKK17174.1 - 4.5e-129 430.2 1.6 6.1e-129 429.8 1.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Lipase_3 PF01764.20 KKK17174.1 - 0.13 11.8 0.0 0.35 10.4 0.0 1.7 1 0 0 1 1 1 0 Lipase (class 3) Menin PF05053.8 KKK17174.1 - 2.6 6.1 6.2 5.5 5.0 4.3 1.4 1 0 0 1 1 1 0 Menin Ribosomal_60s PF00428.14 KKK17174.1 - 3.8 7.9 9.8 1.4 9.3 0.1 3.8 3 0 0 3 3 3 0 60s Acidic ribosomal protein zf-C2H2_4 PF13894.1 KKK17175.1 - 0.00097 19.3 1.2 0.06 13.7 0.0 2.5 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2 PF00096.21 KKK17175.1 - 0.0013 18.9 3.0 0.04 14.2 0.1 2.5 2 0 0 2 2 2 1 Zinc finger, C2H2 type HDV_ag PF01517.13 KKK17175.1 - 0.0019 17.9 0.1 0.004 16.8 0.1 1.5 1 0 0 1 1 1 1 Hepatitis delta virus delta antigen zf-Di19 PF05605.7 KKK17175.1 - 0.11 12.6 1.2 4.6 7.4 0.8 2.3 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding PyrI_C PF02748.10 KKK17175.1 - 5.9 6.4 5.1 10 5.6 0.5 2.4 1 1 1 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Fungal_trans PF04082.13 KKK17177.1 - 6.3e-22 77.6 0.1 1.3e-21 76.6 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK17177.1 - 1.5e-10 40.8 11.1 3e-10 39.8 7.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DAD PF02109.11 KKK17178.1 - 3e-20 72.3 0.4 1.3e-10 41.3 0.0 2.1 2 0 0 2 2 2 2 DAD family Cut8_N PF14482.1 KKK17178.1 - 0.0028 17.6 0.2 0.0035 17.3 0.1 1.3 1 0 0 1 1 1 1 Cut8 proteasome-binding domain Fungal_trans PF04082.13 KKK17179.1 - 4.6e-07 28.9 0.1 7.7e-07 28.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK17179.1 - 0.00057 19.7 11.7 0.00099 18.9 8.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain LicD PF04991.8 KKK17180.1 - 6.7e-17 62.2 0.9 1e-15 58.4 0.6 2.1 1 1 0 1 1 1 1 LicD family HA2 PF04408.18 KKK17181.1 - 1.5e-23 82.6 0.0 5.4e-23 80.9 0.0 2.0 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 KKK17181.1 - 2.9e-22 78.6 0.0 1.5e-20 73.1 0.0 2.5 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 KKK17181.1 - 1.9e-14 53.2 0.0 5.5e-14 51.7 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KKK17181.1 - 2.7e-07 30.2 0.0 1.7e-06 27.6 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KKK17181.1 - 6.4e-05 23.0 0.1 0.00017 21.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 KKK17181.1 - 0.00049 19.0 0.0 0.0022 16.9 0.0 2.1 2 0 0 2 2 2 1 Type II/IV secretion system protein ResIII PF04851.10 KKK17181.1 - 0.00054 19.8 0.3 0.38 10.5 0.0 2.8 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit SRP54 PF00448.17 KKK17181.1 - 0.0024 17.3 0.2 0.0069 15.8 0.1 1.8 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain DUF2075 PF09848.4 KKK17181.1 - 0.0025 16.8 0.0 0.0043 16.0 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) KaiC PF06745.8 KKK17181.1 - 0.005 15.9 0.0 0.0098 15.0 0.0 1.4 1 0 0 1 1 1 1 KaiC AAA_14 PF13173.1 KKK17181.1 - 0.0064 16.4 0.2 0.045 13.6 0.1 2.2 1 1 0 1 1 1 1 AAA domain Flavi_DEAD PF07652.9 KKK17181.1 - 0.012 15.3 0.0 0.023 14.4 0.0 1.4 1 0 0 1 1 1 0 Flavivirus DEAD domain Arch_ATPase PF01637.13 KKK17181.1 - 0.031 13.9 0.0 0.073 12.7 0.0 1.6 1 0 0 1 1 1 0 Archaeal ATPase AAA_23 PF13476.1 KKK17181.1 - 0.069 13.4 0.1 0.27 11.5 0.0 2.1 2 0 0 2 2 1 0 AAA domain ABC_tran PF00005.22 KKK17181.1 - 0.084 13.1 0.1 0.3 11.3 0.0 2.0 2 0 0 2 2 1 0 ABC transporter NB-ARC PF00931.17 KKK17181.1 - 0.11 11.2 0.1 0.19 10.5 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain NACHT PF05729.7 KKK17181.1 - 0.13 11.8 1.1 0.8 9.3 0.8 2.2 1 1 0 1 1 1 0 NACHT domain Prefoldin_2 PF01920.15 KKK17182.1 - 4.1e-26 90.8 6.6 4.9e-26 90.5 4.6 1.1 1 0 0 1 1 1 1 Prefoldin subunit Tho2 PF11262.3 KKK17182.1 - 0.0023 17.0 1.7 0.013 14.6 1.1 1.9 1 1 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 KaiC PF06745.8 KKK17182.1 - 0.0046 16.0 0.2 0.26 10.3 0.0 2.0 1 1 1 2 2 2 1 KaiC GAS PF13851.1 KKK17182.1 - 0.0088 15.2 7.9 0.013 14.7 5.5 1.2 1 1 0 1 1 1 1 Growth-arrest specific micro-tubule binding STAT_alpha PF01017.15 KKK17182.1 - 0.024 14.3 6.0 0.032 13.9 4.1 1.1 1 0 0 1 1 1 0 STAT protein, all-alpha domain IncA PF04156.9 KKK17182.1 - 0.035 13.7 8.5 0.057 13.0 5.9 1.3 1 1 0 1 1 1 0 IncA protein Prefoldin PF02996.12 KKK17182.1 - 0.035 13.7 7.2 0.37 10.4 0.1 2.2 1 1 0 2 2 2 0 Prefoldin subunit DUF641 PF04859.7 KKK17182.1 - 0.051 13.3 3.5 0.17 11.6 0.2 2.0 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) DASH_Dad3 PF08656.5 KKK17182.1 - 0.083 12.5 4.7 0.11 12.2 0.7 2.2 2 0 0 2 2 2 0 DASH complex subunit Dad3 p25-alpha PF05517.7 KKK17182.1 - 0.088 13.0 1.0 0.69 10.1 0.1 2.0 2 0 0 2 2 2 0 p25-alpha DUF2659 PF10858.3 KKK17182.1 - 0.13 11.6 2.3 2.7 7.3 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2659) DUF4200 PF13863.1 KKK17182.1 - 0.17 11.8 7.6 0.11 12.4 1.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) CENP-F_leu_zip PF10473.4 KKK17182.1 - 0.64 9.8 6.8 0.31 10.8 0.9 2.0 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TPR_MLP1_2 PF07926.7 KKK17182.1 - 0.7 9.6 8.5 1.7 8.3 0.2 2.1 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Cytochrom_B562 PF07361.6 KKK17182.1 - 0.74 10.2 5.4 0.51 10.7 1.5 1.9 2 0 0 2 2 2 0 Cytochrome b562 AAA_13 PF13166.1 KKK17182.1 - 0.88 7.9 5.2 1 7.7 3.6 1.0 1 0 0 1 1 1 0 AAA domain Spc24 PF08286.6 KKK17182.1 - 2.6 7.7 7.5 2 8.1 0.9 2.1 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 DUF342 PF03961.8 KKK17182.1 - 3.4 5.9 6.0 7 4.9 4.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF342) TMF_DNA_bd PF12329.3 KKK17182.1 - 6.9 6.5 11.1 0.34 10.7 1.7 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding TFR_dimer PF04253.10 KKK17183.1 - 8.2e-19 67.4 0.0 1.4e-18 66.6 0.0 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.12 KKK17183.1 - 9.2e-15 54.8 0.0 1.6e-14 54.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 KKK17183.1 - 2.8e-08 33.3 0.0 8.3e-08 31.8 0.0 1.8 1 0 0 1 1 1 1 PA domain CMD PF02627.15 KKK17183.1 - 1e-05 25.2 0.0 3.1e-05 23.7 0.0 1.8 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family Nicastrin PF05450.10 KKK17183.1 - 0.0059 15.8 0.0 0.01 15.0 0.0 1.3 1 0 0 1 1 1 1 Nicastrin DUF1356 PF07092.7 KKK17183.1 - 0.2 10.8 0.4 0.33 10.0 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1356) DUF2413 PF10310.4 KKK17184.1 - 2.7e-152 507.6 0.1 3e-152 507.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2413) Flu_M1_C PF08289.6 KKK17184.1 - 0.012 15.5 3.1 0.2 11.7 0.9 2.5 2 0 0 2 2 2 0 Influenza Matrix protein (M1) C-terminal domain RRM_1 PF00076.17 KKK17185.1 - 0.00025 20.6 0.1 0.00045 19.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KKK17185.1 - 0.14 12.1 0.0 0.24 11.4 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Alpha_GJ PF03229.8 KKK17185.1 - 0.32 11.3 5.6 0.35 11.2 3.9 1.0 1 0 0 1 1 1 0 Alphavirus glycoprotein J DUF2985 PF11204.3 KKK17186.1 - 7e-29 99.4 3.9 7e-29 99.4 2.7 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2985) Peptidase_S49_N PF08496.5 KKK17186.1 - 0.1 12.3 0.7 0.21 11.3 0.5 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal GRAM PF02893.15 KKK17187.1 - 2.2e-17 62.3 0.0 5.4e-17 61.0 0.0 1.7 1 0 0 1 1 1 1 GRAM domain Rab_eff_C PF04698.7 KKK17234.1 - 0.016 13.3 0.2 0.018 13.2 0.1 1.0 1 0 0 1 1 1 0 Rab effector MyRIP/melanophilin C-terminus Osmo_CC PF08946.5 KKK17234.1 - 0.031 14.3 5.0 3.1 7.9 0.1 2.5 1 1 1 2 2 2 0 Osmosensory transporter coiled coil Cortex-I_coil PF09304.5 KKK17234.1 - 0.039 13.9 2.3 0.049 13.6 1.6 1.1 1 0 0 1 1 1 0 Cortexillin I, coiled coil SMC_N PF02463.14 KKK17235.1 - 2.2e-23 82.6 0.0 5.1e-23 81.4 0.0 1.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 KKK17235.1 - 2.7e-14 53.9 8.0 2.7e-14 53.9 5.6 5.0 2 2 2 4 4 2 1 AAA domain AAA_21 PF13304.1 KKK17235.1 - 9.9e-06 25.7 3.3 0.0011 18.9 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.1 KKK17235.1 - 0.0021 17.5 0.0 0.0044 16.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.1 KKK17235.1 - 0.016 14.5 0.6 0.083 12.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 KKK17235.1 - 0.063 13.5 0.0 0.063 13.5 0.0 4.4 3 1 0 3 3 2 0 ABC transporter AAA_19 PF13245.1 KKK17235.1 - 0.17 11.6 0.0 0.51 10.1 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain AAA_13 PF13166.1 KKK17235.1 - 0.26 9.6 72.4 0.55 8.6 0.0 4.9 3 2 1 4 4 4 0 AAA domain Reo_sigmaC PF04582.7 KKK17235.1 - 0.26 10.4 12.6 4.2 6.4 0.2 4.2 4 1 0 4 4 4 0 Reovirus sigma C capsid protein AAA PF00004.24 KKK17235.1 - 0.75 9.9 6.6 0.88 9.7 0.0 3.6 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KKK17235.1 - 1.8 9.3 5.9 1.5 9.6 0.0 3.5 2 1 0 2 2 2 0 AAA domain FMN_dh PF01070.13 KKK17236.1 - 6.7e-126 419.9 0.0 7.7e-126 419.7 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase NMO PF03060.10 KKK17236.1 - 3.4e-06 26.4 0.6 6.5e-06 25.5 0.4 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase ThiG PF05690.9 KKK17236.1 - 6.6e-05 22.1 0.1 0.0069 15.4 0.1 2.4 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG Glu_synthase PF01645.12 KKK17236.1 - 0.00083 18.3 0.1 0.0018 17.2 0.1 1.5 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 KKK17236.1 - 0.0023 16.9 0.2 0.0058 15.5 0.1 1.6 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.16 KKK17236.1 - 0.027 13.7 0.2 0.55 9.4 0.0 2.7 2 1 0 3 3 3 0 Histidine biosynthesis protein Lipase_3 PF01764.20 KKK17237.1 - 1.6e-15 56.9 0.0 2.2e-14 53.2 0.0 2.4 1 1 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.2 KKK17237.1 - 0.0043 16.9 0.1 0.0094 15.8 0.1 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KKK17237.1 - 0.0089 15.7 0.0 0.018 14.7 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family MFS_1 PF07690.11 KKK17239.1 - 1e-34 119.8 27.6 7.1e-34 117.0 19.7 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily NADH-u_ox-rdase PF10785.4 KKK17239.1 - 2.2 8.5 6.3 1.6 8.9 0.1 3.4 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit NAC PF01849.13 KKK17240.1 - 5.2e-22 77.1 0.3 8.6e-22 76.4 0.2 1.4 1 0 0 1 1 1 1 NAC domain zf-C2H2 PF00096.21 KKK17241.1 - 3.9e-07 30.0 15.5 0.0027 17.9 3.1 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KKK17241.1 - 1.9e-05 24.7 11.9 2e-05 24.6 0.6 3.4 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 KKK17241.1 - 0.019 15.2 13.4 0.083 13.2 1.6 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger zf-met PF12874.2 KKK17241.1 - 0.17 12.1 4.1 0.36 11.1 1.4 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Zn-ribbon_8 PF09723.5 KKK17241.1 - 0.19 11.7 1.9 3.3 7.7 0.2 2.4 2 0 0 2 2 2 0 Zinc ribbon domain zf-BED PF02892.10 KKK17241.1 - 0.35 10.6 11.6 0.76 9.5 2.2 2.5 1 1 1 2 2 2 0 BED zinc finger PALP PF00291.20 KKK17242.1 - 2.3e-11 43.4 0.5 3.1e-08 33.2 0.0 2.0 1 1 1 2 2 2 2 Pyridoxal-phosphate dependent enzyme Fungal_trans PF04082.13 KKK17245.1 - 2.5e-08 33.0 0.1 4.1e-08 32.4 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain p450 PF00067.17 KKK17246.1 - 0.0039 15.7 0.0 0.0057 15.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_3 PF01494.14 KKK17247.1 - 3.8e-29 101.8 0.0 3.3e-28 98.7 0.0 1.9 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 KKK17247.1 - 1.2e-05 25.2 0.0 2.4e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain SE PF08491.5 KKK17247.1 - 6.1e-05 21.9 0.0 0.0034 16.2 0.0 2.1 2 0 0 2 2 2 1 Squalene epoxidase DAO PF01266.19 KKK17247.1 - 0.0001 21.3 0.0 0.013 14.4 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KKK17247.1 - 0.00021 20.3 0.4 0.057 12.3 0.0 2.9 3 0 0 3 3 3 1 Lycopene cyclase protein Trp_halogenase PF04820.9 KKK17247.1 - 0.00025 19.8 0.1 0.64 8.5 0.0 2.9 3 0 0 3 3 3 2 Tryptophan halogenase HI0933_like PF03486.9 KKK17247.1 - 0.00031 19.3 0.0 0.016 13.7 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.9 KKK17247.1 - 0.00038 20.3 0.1 0.00088 19.1 0.1 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KKK17247.1 - 0.0014 17.5 0.0 0.003 16.4 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 KKK17247.1 - 0.011 15.7 0.0 0.092 12.7 0.0 2.4 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KKK17247.1 - 0.02 15.2 0.0 2.3 8.6 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KKK17247.1 - 0.02 14.6 0.1 0.047 13.4 0.1 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding Amino_oxidase PF01593.19 KKK17247.1 - 0.039 13.0 0.0 5 6.0 0.0 2.2 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase GST_C_2 PF13410.1 KKK17249.1 - 1.5e-08 34.4 1.5 3.4e-08 33.2 0.8 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 KKK17249.1 - 1.6e-07 31.3 0.0 3.3e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KKK17249.1 - 8.5e-07 28.8 0.0 1.9e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KKK17249.1 - 0.0037 17.2 0.0 0.0071 16.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KKK17249.1 - 0.0069 16.8 0.0 0.011 16.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_4 PF14834.1 KKK17249.1 - 0.14 12.0 0.1 0.33 10.9 0.1 1.6 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain OmdA PF13376.1 KKK17249.1 - 0.92 9.2 3.3 0.27 10.9 0.2 1.7 2 0 0 2 2 2 0 Bacteriocin-protection, YdeI or OmpD-Associated Cation_efflux PF01545.16 KKK17250.1 - 8.2e-72 241.6 4.6 9.8e-72 241.4 3.2 1.1 1 0 0 1 1 1 1 Cation efflux family BPD_transp_2 PF02653.11 KKK17250.1 - 0.00031 19.8 0.0 0.00031 19.8 0.0 1.8 2 1 0 2 2 2 1 Branched-chain amino acid transport system / permease component APH PF01636.18 KKK17251.1 - 0.00096 18.9 0.7 0.00096 18.9 0.5 3.0 2 2 0 2 2 2 1 Phosphotransferase enzyme family HSDR_N_2 PF13588.1 KKK17251.1 - 0.004 16.9 0.0 0.36 10.6 0.0 2.5 2 0 0 2 2 2 1 Type I restriction enzyme R protein N terminus (HSDR_N) Spore_coat_CotO PF14153.1 KKK17251.1 - 0.01 15.3 14.0 0.013 14.9 5.5 2.3 2 0 0 2 2 2 1 Spore coat protein CotO SPX PF03105.14 KKK17251.1 - 0.66 9.7 14.4 2.4 7.8 3.4 2.3 2 0 0 2 2 2 0 SPX domain OmpH PF03938.9 KKK17251.1 - 9.2 6.1 18.7 11 5.9 10.4 2.4 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Glyco_hydro_76 PF03663.9 KKK17252.1 - 5.1e-136 453.9 22.9 7e-136 453.4 15.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 TPR_12 PF13424.1 KKK17253.1 - 1.5e-09 37.6 29.0 0.00014 21.7 0.1 9.5 10 0 0 10 10 10 3 Tetratricopeptide repeat AAA_22 PF13401.1 KKK17253.1 - 9.2e-07 29.0 0.2 0.0014 18.7 0.0 3.5 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 KKK17253.1 - 3.3e-06 27.2 5.1 8.8e-06 25.8 0.0 4.3 4 2 1 5 5 5 1 AAA ATPase domain NACHT PF05729.7 KKK17253.1 - 1.3e-05 24.8 0.0 5.5e-05 22.8 0.0 2.1 1 0 0 1 1 1 1 NACHT domain TPR_14 PF13428.1 KKK17253.1 - 0.023 15.3 18.7 16 6.4 0.0 8.1 9 0 0 9 9 9 0 Tetratricopeptide repeat Abhydrolase_3 PF07859.8 KKK17254.1 - 3.2e-54 183.7 0.0 3.9e-54 183.4 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KKK17254.1 - 1.3e-06 28.2 0.0 1.8e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2424 PF10340.4 KKK17254.1 - 5.9e-06 25.1 0.0 7.7e-06 24.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) COesterase PF00135.23 KKK17254.1 - 4.6e-05 22.3 0.1 0.0015 17.2 0.0 2.1 2 0 0 2 2 2 1 Carboxylesterase family Chlorophyllase2 PF12740.2 KKK17254.1 - 8.5e-05 21.5 0.0 0.00013 20.9 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme DUF2305 PF10230.4 KKK17254.1 - 0.00078 18.9 0.0 0.0012 18.3 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Esterase PF00756.15 KKK17254.1 - 0.0059 16.0 0.0 0.033 13.6 0.0 1.9 1 1 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.16 KKK17254.1 - 0.028 13.6 0.0 0.043 13.0 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family Glyco_transf_28 PF03033.15 KKK17255.1 - 5.2e-17 61.9 0.1 2.8e-15 56.3 0.0 2.4 2 0 0 2 2 2 2 Glycosyltransferase family 28 N-terminal domain Pyr_redox PF00070.22 KKK17256.1 - 4.5e-16 59.0 0.0 5.3e-12 45.9 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KKK17256.1 - 5.3e-12 46.0 0.1 0.0018 18.2 0.0 3.9 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KKK17256.1 - 5.6e-11 41.9 0.0 0.0017 17.3 0.0 3.2 3 0 0 3 3 3 3 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KKK17256.1 - 4.1e-08 33.5 0.0 0.0029 17.6 0.0 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KKK17256.1 - 1.4e-07 30.7 0.1 6.9e-07 28.4 0.0 2.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_7 PF13241.1 KKK17256.1 - 1.1e-05 25.5 0.0 0.0025 18.0 0.0 2.3 2 0 0 2 2 2 1 Putative NAD(P)-binding TrkA_N PF02254.13 KKK17256.1 - 0.00011 22.1 0.0 0.084 12.8 0.0 3.1 4 0 0 4 4 4 1 TrkA-N domain Trp_halogenase PF04820.9 KKK17256.1 - 0.00027 19.7 0.0 0.24 9.9 0.0 2.2 2 0 0 2 2 2 2 Tryptophan halogenase NAD_binding_8 PF13450.1 KKK17256.1 - 0.00031 20.6 0.1 0.96 9.5 0.0 2.7 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 KKK17256.1 - 0.0036 17.0 0.0 17 5.1 0.0 4.0 4 0 0 4 4 4 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 KKK17256.1 - 0.0058 15.5 0.0 0.09 11.6 0.0 2.3 2 1 0 2 2 2 1 Lycopene cyclase protein THF_DHG_CYH_C PF02882.14 KKK17256.1 - 0.013 14.5 0.5 0.27 10.3 0.0 2.6 3 0 0 3 3 3 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF4147 PF13660.1 KKK17256.1 - 0.044 12.9 0.2 0.12 11.4 0.0 1.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4147) UDPG_MGDP_dh_N PF03721.9 KKK17256.1 - 0.052 12.9 0.0 2.8 7.2 0.0 2.3 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain SIS PF01380.17 KKK17256.1 - 0.12 11.9 0.1 3 7.4 0.0 2.3 2 0 0 2 2 2 0 SIS domain Aminotran_4 PF01063.14 KKK17257.1 - 8.3e-22 77.7 0.0 1.3e-21 77.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class IV FAD_binding_7 PF03441.9 KKK17258.1 - 6.4e-102 340.4 0.6 1.1e-101 339.7 0.4 1.4 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 KKK17258.1 - 2.6e-41 141.1 0.3 4.8e-41 140.2 0.2 1.4 1 0 0 1 1 1 1 DNA photolyase Fungal_trans PF04082.13 KKK17259.1 - 2.7e-21 75.6 0.0 1.3e-20 73.4 0.0 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK17259.1 - 1.9e-09 37.2 11.8 3.6e-09 36.3 8.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mucin PF01456.12 KKK17259.1 - 0.0055 16.4 25.8 0.014 15.1 17.9 1.6 1 0 0 1 1 1 1 Mucin-like glycoprotein Zn_clus PF00172.13 KKK17260.1 - 1.7e-05 24.6 13.3 1.7e-05 24.6 9.2 2.3 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1840 PF08895.6 KKK17260.1 - 0.09 12.7 0.6 0.21 11.6 0.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1840) BUD22 PF09073.5 KKK17260.1 - 0.6 9.1 8.5 0.82 8.6 5.9 1.1 1 0 0 1 1 1 0 BUD22 DUF2890 PF11081.3 KKK17260.1 - 0.82 9.6 6.6 1.4 8.9 4.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Glyco_hydro_16 PF00722.16 KKK17261.1 - 0.0045 16.2 0.5 0.035 13.3 0.1 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 Peptidase_C48 PF02902.14 KKK17262.1 - 1.7e-25 89.9 0.0 3.2e-25 89.0 0.0 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain AAA_13 PF13166.1 KKK17263.1 - 3e-05 22.7 0.6 0.00014 20.4 0.1 1.9 1 1 1 2 2 2 1 AAA domain WEMBL PF05701.6 KKK17263.1 - 0.001 17.6 1.3 0.0016 17.0 0.9 1.2 1 0 0 1 1 1 1 Weak chloroplast movement under blue light Reo_sigmaC PF04582.7 KKK17263.1 - 0.0013 18.0 9.1 0.006 15.7 6.3 2.0 1 1 0 1 1 1 1 Reovirus sigma C capsid protein Spc7 PF08317.6 KKK17263.1 - 0.0017 17.1 2.4 0.0026 16.4 1.6 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein CENP-F_leu_zip PF10473.4 KKK17263.1 - 0.0017 18.2 6.0 0.05 13.4 0.4 2.9 2 1 1 3 3 3 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 LPP PF04728.8 KKK17263.1 - 0.0022 17.7 7.3 0.0041 16.8 0.7 3.1 1 1 1 3 3 3 2 Lipoprotein leucine-zipper Cast PF10174.4 KKK17263.1 - 0.0023 16.0 3.2 0.0023 16.0 2.2 1.4 2 0 0 2 2 2 1 RIM-binding protein of the cytomatrix active zone ATG16 PF08614.6 KKK17263.1 - 0.0025 17.6 4.0 0.011 15.6 2.8 2.0 1 1 0 1 1 1 1 Autophagy protein 16 (ATG16) DUF1664 PF07889.7 KKK17263.1 - 0.0034 17.1 1.8 0.44 10.3 1.4 3.3 2 1 1 3 3 3 1 Protein of unknown function (DUF1664) Atg14 PF10186.4 KKK17263.1 - 0.0068 15.3 1.2 0.0068 15.3 0.8 2.0 1 1 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 DUF4618 PF15397.1 KKK17263.1 - 0.0071 15.7 2.1 0.81 8.9 0.1 2.9 1 1 0 2 2 2 1 Domain of unknown function (DUF4618) HALZ PF02183.13 KKK17263.1 - 0.0079 15.8 0.2 3.2 7.5 0.0 3.1 3 1 0 3 3 2 1 Homeobox associated leucine zipper AIP3 PF03915.8 KKK17263.1 - 0.0084 15.0 3.7 0.016 14.1 2.6 1.5 1 0 0 1 1 1 1 Actin interacting protein 3 TBPIP PF07106.8 KKK17263.1 - 0.03 13.8 0.3 0.062 12.8 0.2 1.6 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Transcrip_act PF04949.8 KKK17263.1 - 0.036 13.7 0.4 0.14 11.8 0.1 2.1 1 1 0 1 1 1 0 Transcriptional activator TSC22 PF01166.13 KKK17263.1 - 0.039 13.9 0.9 2.1 8.3 0.0 2.8 2 1 1 3 3 2 0 TSC-22/dip/bun family Myosin_tail_1 PF01576.14 KKK17263.1 - 0.052 11.2 3.5 0.016 12.9 0.6 1.4 2 0 0 2 2 2 0 Myosin tail NPV_P10 PF05531.7 KKK17263.1 - 0.053 13.7 5.2 0.16 12.2 0.6 3.1 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Seryl_tRNA_N PF02403.17 KKK17263.1 - 0.064 13.2 0.2 0.15 12.1 0.1 1.6 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain ADIP PF11559.3 KKK17263.1 - 0.069 13.0 3.2 0.29 11.0 0.4 2.3 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding COG7 PF10191.4 KKK17263.1 - 0.069 11.0 2.0 0.64 7.8 0.3 2.0 1 1 1 2 2 2 0 Golgi complex component 7 (COG7) MscS_porin PF12795.2 KKK17263.1 - 0.087 12.1 0.4 0.32 10.2 0.2 1.8 1 1 0 1 1 1 0 Mechanosensitive ion channel porin domain DUF972 PF06156.8 KKK17263.1 - 0.11 12.8 1.2 1.8 8.9 0.0 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF972) IncA PF04156.9 KKK17263.1 - 0.24 10.9 7.7 0.87 9.1 5.2 2.0 1 1 1 2 2 2 0 IncA protein COG5 PF10392.4 KKK17263.1 - 0.27 11.1 9.0 0.21 11.5 0.7 3.4 1 1 3 4 4 4 0 Golgi transport complex subunit 5 DUF1640 PF07798.6 KKK17263.1 - 0.29 11.1 3.5 6.5 6.7 0.1 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1640) Baculo_PEP_C PF04513.7 KKK17263.1 - 0.34 10.7 6.1 0.06 13.1 1.3 1.8 2 1 0 2 2 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Sec8_exocyst PF04048.9 KKK17263.1 - 0.54 9.8 5.1 0.24 11.0 0.7 2.3 2 1 1 3 3 2 0 Sec8 exocyst complex component specific domain Lge1 PF11488.3 KKK17263.1 - 2.4 8.4 6.0 6.8 6.9 1.8 3.1 2 1 0 2 2 1 0 Transcriptional regulatory protein LGE1 PAP2 PF01569.16 KKK17264.1 - 6.1e-17 61.5 3.0 6.1e-17 61.5 2.1 2.1 2 1 0 2 2 2 1 PAP2 superfamily DUF4512 PF14975.1 KKK17264.1 - 0.11 13.3 0.1 0.22 12.3 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4512) Ras PF00071.17 KKK17265.1 - 1.5e-48 164.2 0.0 1.9e-48 163.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KKK17265.1 - 6.8e-12 45.9 0.0 1e-11 45.3 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KKK17265.1 - 5.1e-05 22.5 0.0 0.00017 20.9 0.0 1.8 1 1 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 KKK17265.1 - 0.032 13.4 0.0 0.051 12.7 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 KKK17265.1 - 0.034 13.2 0.0 0.048 12.7 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region adh_short PF00106.20 KKK17266.1 - 2.6e-15 56.7 0.2 4.5e-15 55.9 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KKK17266.1 - 8.5e-08 32.0 0.1 1.2e-07 31.5 0.1 1.3 1 0 0 1 1 1 1 KR domain NmrA PF05368.8 KKK17266.1 - 0.023 13.9 0.3 0.04 13.1 0.0 1.4 2 0 0 2 2 2 0 NmrA-like family Permease PF02405.11 KKK17266.1 - 0.072 12.5 0.1 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Permease zf-HIT PF04438.11 KKK17267.1 - 3.5e-10 39.3 9.9 5.6e-10 38.6 6.8 1.3 1 0 0 1 1 1 1 HIT zinc finger BAF1_ABF1 PF04684.8 KKK17267.1 - 1.7 7.4 12.3 2.6 6.7 8.6 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DEP PF00610.16 KKK17268.1 - 1.3e-24 85.6 0.0 7.7e-18 64.0 0.0 3.3 2 1 0 2 2 2 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) RGS PF00615.14 KKK17268.1 - 4.7e-10 39.5 0.1 1.3e-09 38.2 0.1 1.7 1 0 0 1 1 1 1 Regulator of G protein signaling domain MFS_1 PF07690.11 KKK17273.1 - 1.1e-44 152.6 47.3 6.5e-44 150.0 32.8 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KKK17273.1 - 2.5e-09 36.2 27.8 1.4e-08 33.7 10.1 2.5 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_2 PF13347.1 KKK17273.1 - 5.3e-09 34.9 30.2 0.00021 19.8 4.4 3.1 1 1 1 2 2 2 2 MFS/sugar transport protein Thiolase_N PF00108.18 KKK17274.1 - 2.5e-84 282.3 0.1 3.9e-84 281.7 0.0 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 KKK17274.1 - 1.1e-37 128.2 1.0 1.1e-37 128.2 0.7 2.5 2 1 2 4 4 4 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 KKK17274.1 - 2.9e-05 23.7 3.1 4.3e-05 23.1 1.5 1.9 2 1 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Chal_sti_synt_N PF00195.14 KKK17274.1 - 0.099 11.8 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 Chalcone and stilbene synthases, N-terminal domain Peptidase_C2 PF00648.16 KKK17275.1 - 2.9e-44 151.2 7.0 1.3e-24 86.7 1.0 3.2 3 1 0 3 3 3 2 Calpain family cysteine protease Pkinase PF00069.20 KKK17276.1 - 3e-71 239.6 0.0 3.6e-71 239.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK17276.1 - 8.7e-31 106.9 0.0 1.1e-30 106.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KKK17276.1 - 0.0027 16.7 0.0 0.0044 16.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KKK17276.1 - 0.0031 17.2 0.7 0.006 16.3 0.1 1.7 2 1 0 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 KKK17276.1 - 0.014 14.2 0.0 0.022 13.6 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 YrbL-PhoP_reg PF10707.4 KKK17276.1 - 0.082 12.2 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Abhydrolase_6 PF12697.2 KKK17277.1 - 3.2e-28 99.1 0.6 3.2e-28 99.1 0.4 1.9 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KKK17277.1 - 1.8e-15 57.1 0.0 7.7e-13 48.5 0.0 3.0 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KKK17277.1 - 1.8e-10 40.7 0.0 4.7e-10 39.3 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.9 KKK17277.1 - 0.0001 20.9 0.0 0.00021 19.8 0.0 1.5 1 1 0 1 1 1 1 Ndr family EthD PF07110.6 KKK17277.1 - 0.036 14.9 0.1 5.6 7.9 0.0 2.7 2 0 0 2 2 2 0 EthD domain Aldedh PF00171.17 KKK17315.1 - 1.2e-104 350.2 0.9 6.7e-101 337.8 0.1 2.1 1 1 1 2 2 2 2 Aldehyde dehydrogenase family HnRNPA1 PF11627.3 KKK17315.1 - 0.2 11.8 0.7 0.42 10.8 0.5 1.5 1 0 0 1 1 1 0 Nuclear factor hnRNPA1 Hexapep PF00132.19 KKK17334.1 - 5.9e-10 38.1 17.3 0.0086 15.5 2.5 4.5 2 2 2 4 4 4 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 KKK17334.1 - 0.00038 19.9 7.0 0.0022 17.5 0.4 3.1 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase GNAT_acetyltr_2 PF13718.1 KKK17335.1 - 1e-78 263.2 0.0 1.6e-78 262.5 0.0 1.3 1 0 0 1 1 1 1 GNAT acetyltransferase 2 Helicase_RecD PF05127.9 KKK17335.1 - 1.7e-66 223.2 0.0 4.5e-66 221.8 0.0 1.7 2 0 0 2 2 2 1 Helicase DUF1726 PF08351.6 KKK17335.1 - 3.8e-40 135.4 0.0 9.7e-40 134.1 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) tRNA_bind_2 PF13725.1 KKK17335.1 - 9e-37 125.2 0.5 2.8e-36 123.6 0.3 1.9 1 0 0 1 1 1 1 Possible tRNA binding domain AAA_19 PF13245.1 KKK17335.1 - 0.051 13.3 0.3 0.46 10.2 0.0 2.5 2 0 0 2 2 2 0 Part of AAA domain Acetyltransf_1 PF00583.19 KKK17335.1 - 0.08 12.9 0.0 0.39 10.7 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KKK17335.1 - 0.11 12.6 0.0 0.34 11.1 0.0 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Topoisom_I_N PF02919.10 KKK17336.1 - 2.3e-95 317.9 1.5 2.3e-95 317.9 1.1 3.5 4 0 0 4 4 4 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.15 KKK17336.1 - 1.1e-82 276.7 8.6 1.1e-82 276.7 6.0 2.1 3 0 0 3 3 3 1 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.1 KKK17336.1 - 4.1e-33 112.8 0.5 1.2e-32 111.3 0.3 1.9 1 0 0 1 1 1 1 C-terminal topoisomerase domain RolB_RolC PF02027.12 KKK17336.1 - 0.1 11.7 0.0 0.28 10.3 0.0 1.7 1 0 0 1 1 1 0 RolB/RolC glucosidase family ATP-synt PF00231.14 KKK17337.1 - 2.3e-66 224.1 7.4 2.7e-66 223.9 5.1 1.0 1 0 0 1 1 1 1 ATP synthase Glyco_trans_1_4 PF13692.1 KKK17337.1 - 0.049 13.7 0.0 0.076 13.1 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferases group 1 DnaJ PF00226.26 KKK17338.1 - 5.1e-19 67.7 0.2 1.2e-18 66.6 0.2 1.7 1 0 0 1 1 1 1 DnaJ domain DUF3723 PF12520.3 KKK17338.1 - 0.0015 17.0 1.8 0.0022 16.5 1.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3723) Thioredoxin PF00085.15 KKK17339.1 - 3.6e-31 106.9 0.0 3.1e-25 87.8 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.1 KKK17339.1 - 1.3e-08 34.9 0.6 3.2e-06 27.3 0.4 2.9 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_6 PF13848.1 KKK17339.1 - 5.4e-07 29.5 0.0 1e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 KKK17339.1 - 8.7e-06 25.7 0.0 0.0015 18.6 0.0 3.6 3 2 0 3 3 3 1 Thioredoxin-like Thioredoxin_3 PF13192.1 KKK17339.1 - 0.0034 17.1 0.0 0.56 10.0 0.1 2.5 2 0 0 2 2 2 1 Thioredoxin domain AhpC-TSA PF00578.16 KKK17339.1 - 0.0086 15.7 0.1 0.027 14.1 0.0 1.8 2 0 0 2 2 2 1 AhpC/TSA family Thioredoxin_7 PF13899.1 KKK17339.1 - 0.026 14.5 0.0 0.079 12.9 0.0 1.8 2 0 0 2 2 2 0 Thioredoxin-like EutB PF06751.6 KKK17339.1 - 0.15 10.3 0.0 0.23 9.7 0.0 1.1 1 0 0 1 1 1 0 Ethanolamine ammonia lyase large subunit (EutB) F-box PF00646.28 KKK17340.1 - 1.2e-07 31.1 0.1 4.6e-07 29.3 0.0 2.0 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KKK17340.1 - 3.9e-07 29.6 1.7 5e-07 29.3 0.2 2.0 2 0 0 2 2 2 1 F-box-like Sugar_tr PF00083.19 KKK17341.1 - 1.2e-108 363.6 16.8 2.5e-108 362.5 11.6 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KKK17341.1 - 5.9e-25 87.7 28.1 3.4e-18 65.5 6.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily WD40 PF00400.27 KKK17356.1 - 6.8e-68 222.3 21.3 2.5e-11 42.9 0.4 7.5 7 1 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 KKK17356.1 - 9.6e-06 24.0 3.7 0.00083 17.6 0.4 3.4 3 1 0 3 3 3 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 KKK17356.1 - 0.00095 18.0 0.4 6.7 5.3 0.0 3.2 2 1 1 3 3 3 3 Nup133 N terminal like Hira PF07569.6 KKK17356.1 - 0.038 13.2 0.2 6.7 5.8 0.1 2.4 2 0 0 2 2 2 0 TUP1-like enhancer of split SlyX PF04102.7 KKK17356.1 - 0.11 12.8 0.0 0.22 11.9 0.0 1.4 1 0 0 1 1 1 0 SlyX Cytochrom_D1 PF02239.11 KKK17356.1 - 0.12 10.6 0.0 0.49 8.6 0.0 1.8 2 0 0 2 2 2 0 Cytochrome D1 heme domain Peptidase_M19 PF01244.16 KKK17357.1 - 2.5e-103 345.3 0.0 3.2e-103 345.0 0.0 1.1 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) NOC3p PF07540.6 KKK17367.1 - 2.4e-35 120.6 0.3 2.4e-35 120.6 0.2 2.2 2 0 0 2 2 2 1 Nucleolar complex-associated protein CBF PF03914.12 KKK17367.1 - 4.7e-33 113.9 0.0 4.7e-33 113.9 0.0 2.4 3 0 0 3 3 3 1 CBF/Mak21 family DUF2570 PF10828.3 KKK17367.1 - 0.44 10.1 2.5 1.1 8.8 1.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) PLA2_B PF01735.13 KKK17368.1 - 1.7e-26 92.4 0.0 3e-26 91.6 0.0 1.4 1 0 0 1 1 1 1 Lysophospholipase catalytic domain RE_NgoPII PF09521.5 KKK17368.1 - 0.23 10.1 0.0 0.38 9.5 0.0 1.2 1 0 0 1 1 1 0 NgoPII restriction endonuclease DSPc PF00782.15 KKK17369.1 - 5.6e-10 38.9 0.0 1e-09 38.0 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KKK17369.1 - 0.0047 16.2 0.0 0.0079 15.5 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 KKK17369.1 - 0.089 13.0 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family Cellulose_synt PF03552.9 KKK17369.1 - 0.22 9.7 0.0 0.31 9.2 0.0 1.1 1 0 0 1 1 1 0 Cellulose synthase PPR_3 PF13812.1 KKK17370.1 - 1.2e-14 53.2 0.8 0.09 13.0 0.1 8.2 8 0 0 8 8 8 3 Pentatricopeptide repeat domain PPR_2 PF13041.1 KKK17370.1 - 3.2e-14 52.6 0.1 0.0013 18.6 0.0 6.6 4 3 3 7 7 7 3 PPR repeat family PPR PF01535.15 KKK17370.1 - 1.7e-09 36.9 2.6 0.035 14.0 0.1 5.5 6 0 0 6 6 6 3 PPR repeat PPR_1 PF12854.2 KKK17370.1 - 0.017 14.6 0.0 0.41 10.1 0.0 2.9 3 0 0 3 3 3 0 PPR repeat LSM PF01423.17 KKK17371.1 - 7.9e-12 44.5 0.0 8.2e-12 44.4 0.0 1.1 1 0 0 1 1 1 1 LSM domain Exo70 PF03081.10 KKK17372.1 - 5.3e-78 262.3 0.0 8.2e-78 261.7 0.0 1.3 1 0 0 1 1 1 1 Exo70 exocyst complex subunit Lyase_1 PF00206.15 KKK17373.1 - 5.2e-21 75.1 0.0 9.9e-21 74.2 0.0 1.4 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.4 KKK17373.1 - 5.6e-17 61.5 0.0 1.6e-16 60.0 0.0 1.8 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus Hat1_N PF10394.4 KKK17376.1 - 1.4e-49 168.2 0.0 2.4e-49 167.4 0.0 1.4 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus 3HCDH_N PF02737.13 KKK17377.1 - 4.9e-23 81.6 0.8 2.9e-21 75.9 0.0 2.3 1 1 1 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 KKK17377.1 - 5.4e-10 39.5 0.0 2.3e-09 37.5 0.0 1.9 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain Zip PF02535.17 KKK17378.1 - 1.3e-38 132.7 10.6 8.6e-29 100.5 2.8 3.0 2 1 0 2 2 2 2 ZIP Zinc transporter ABC2_membrane_5 PF13346.1 KKK17378.1 - 1.6 7.9 8.5 0.08 12.2 1.0 2.3 3 0 0 3 3 3 0 ABC-2 family transporter protein WD40 PF00400.27 KKK17379.1 - 1.6e-51 170.4 17.1 2.6e-09 36.6 0.3 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat F-box-like PF12937.2 KKK17379.1 - 1.2e-10 40.9 0.4 2.2e-10 40.0 0.3 1.4 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.3 KKK17379.1 - 2.6e-10 39.0 6.1 6.6e-05 21.2 0.1 4.7 1 1 4 5 5 5 4 Nucleoporin Nup120/160 F-box PF00646.28 KKK17379.1 - 0.00042 19.8 0.3 0.00092 18.8 0.2 1.6 1 0 0 1 1 1 1 F-box domain PQQ_3 PF13570.1 KKK17379.1 - 1.6 9.1 10.2 63 4.0 0.0 5.1 4 2 2 6 6 6 0 PQQ-like domain BCDHK_Adom3 PF10436.4 KKK17380.1 - 1.7e-70 235.8 0.0 2.3e-70 235.3 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 KKK17380.1 - 1.1e-13 50.9 0.0 2.4e-13 49.7 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 KKK17380.1 - 0.038 13.6 0.0 0.075 12.6 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Crust_neurohorm PF01147.12 KKK17380.1 - 0.17 11.2 0.1 0.36 10.1 0.0 1.4 1 0 0 1 1 1 0 Crustacean CHH/MIH/GIH neurohormone family Glycophorin_A PF01102.13 KKK17413.1 - 0.17 11.6 1.1 0.26 11.0 0.7 1.7 1 1 0 1 1 1 0 Glycophorin A PX PF00787.19 KKK17414.1 - 2.8e-19 68.9 0.0 4.1e-19 68.4 0.0 1.2 1 0 0 1 1 1 1 PX domain RPN7 PF10602.4 KKK17415.1 - 1e-56 191.1 0.1 1.9e-56 190.2 0.1 1.5 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 KKK17415.1 - 1.3e-10 41.5 0.9 3.4e-10 40.1 0.1 2.1 3 0 0 3 3 3 1 PCI domain NTR2 PF15458.1 KKK17416.1 - 6.4e-80 268.0 25.0 9.2e-80 267.5 17.4 1.2 1 0 0 1 1 1 1 Nineteen complex-related protein 2 LSM PF01423.17 KKK17417.1 - 7.4e-20 70.2 0.3 8.4e-20 70.1 0.2 1.0 1 0 0 1 1 1 1 LSM domain ATP_transf PF09830.4 KKK17418.1 - 5.3e-23 80.5 0.0 1e-22 79.6 0.0 1.5 1 0 0 1 1 1 1 ATP adenylyltransferase GalP_UDP_transf PF01087.17 KKK17418.1 - 0.033 14.2 0.0 0.08 12.9 0.0 1.6 2 0 0 2 2 2 0 Galactose-1-phosphate uridyl transferase, N-terminal domain Peptidase_M1 PF01433.15 KKK17420.1 - 2.2e-08 33.6 0.0 0.017 14.2 0.0 3.2 3 0 0 3 3 3 3 Peptidase family M1 CDP-OH_P_transf PF01066.16 KKK17421.1 - 4.2e-18 65.5 1.0 4.2e-18 65.5 0.7 2.4 3 0 0 3 3 3 1 CDP-alcohol phosphatidyltransferase Sdh_cyt PF01127.17 KKK17422.1 - 5.1e-25 87.6 3.0 5.1e-25 87.6 2.0 1.7 2 0 0 2 2 2 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Transaldolase PF00923.14 KKK17423.1 - 7.5e-50 169.6 0.0 9e-50 169.4 0.0 1.0 1 0 0 1 1 1 1 Transaldolase Adap_comp_sub PF00928.16 KKK17424.1 - 3.7e-90 301.5 0.0 4.7e-90 301.2 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 KKK17424.1 - 6.7e-09 35.6 0.3 1.1e-08 34.8 0.2 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Ribonucleas_3_3 PF14622.1 KKK17425.1 - 3e-29 101.5 0.0 5.9e-29 100.6 0.0 1.5 1 1 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.21 KKK17425.1 - 1.3e-06 28.7 0.0 2.9e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 Ribonuclease III domain FGGY_C PF02782.11 KKK17426.1 - 1.3e-33 116.2 0.0 2.3e-33 115.4 0.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 KKK17426.1 - 8.1e-22 77.7 0.0 2.1e-13 50.1 0.0 2.4 2 1 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain Xpo1 PF08389.7 KKK17427.1 - 3.7e-44 150.2 0.1 3.6e-43 147.0 0.0 2.8 2 0 0 2 2 2 1 Exportin 1-like protein HEAT PF02985.17 KKK17427.1 - 7.4e-05 22.5 0.1 0.6 10.3 0.0 4.8 4 0 0 4 4 4 1 HEAT repeat TctA PF01970.11 KKK17427.1 - 0.024 13.0 0.0 0.042 12.2 0.0 1.3 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctA family Tom22 PF04281.8 KKK17427.1 - 0.036 13.6 0.6 8.3 5.9 0.0 2.5 2 0 0 2 2 2 0 Mitochondrial import receptor subunit Tom22 Cation_efflux PF01545.16 KKK17428.1 - 6.3e-64 215.7 0.5 7.7e-64 215.5 0.4 1.1 1 0 0 1 1 1 1 Cation efflux family TrkH PF02386.11 KKK17428.1 - 0.046 12.2 0.2 0.1 11.1 0.1 1.5 1 1 1 2 2 2 0 Cation transport protein DUF808 PF05661.7 KKK17428.1 - 0.17 10.6 3.8 2.7 6.7 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF808) PAP2_3 PF14378.1 KKK17430.1 - 7.2e-49 165.9 10.2 9.9e-49 165.4 7.1 1.2 1 0 0 1 1 1 1 PAP2 superfamily PAP2 PF01569.16 KKK17430.1 - 8.8e-05 22.1 10.5 9.3e-05 22.1 5.5 2.2 1 1 1 2 2 2 1 PAP2 superfamily PAP2_C PF14360.1 KKK17430.1 - 0.15 12.3 7.5 0.047 13.9 1.4 2.5 2 0 0 2 2 2 0 PAP2 superfamily C-terminal Mito_carr PF00153.22 KKK17431.1 - 9.3e-40 134.2 0.1 4.4e-25 87.2 0.0 2.6 2 1 1 3 3 3 2 Mitochondrial carrier protein EF-hand_6 PF13405.1 KKK17431.1 - 2e-19 67.6 2.3 7.8e-07 28.4 0.1 5.5 5 0 0 5 5 5 2 EF-hand domain EF-hand_7 PF13499.1 KKK17431.1 - 1.3e-18 66.8 4.3 1e-08 35.1 0.5 3.6 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.27 KKK17431.1 - 2.2e-18 64.0 2.8 3.5e-07 29.0 0.0 5.4 6 0 0 6 6 6 4 EF hand EF-hand_8 PF13833.1 KKK17431.1 - 9.1e-16 57.2 5.8 0.00091 18.7 0.1 5.4 4 2 2 6 6 6 5 EF-hand domain pair EF-hand_5 PF13202.1 KKK17431.1 - 1.1e-13 49.7 0.8 1.9e-05 23.7 0.1 4.7 5 0 0 5 5 5 3 EF hand EF-hand_9 PF14658.1 KKK17431.1 - 0.0009 19.1 0.1 2.4 8.1 0.0 3.4 3 0 0 3 3 3 2 EF-hand domain 6PGD PF00393.14 KKK17438.1 - 6.5e-60 202.7 0.0 1.1e-59 202.0 0.0 1.3 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain PNP_UDP_1 PF01048.15 KKK17438.1 - 5.4e-37 126.9 0.1 8.5e-37 126.3 0.1 1.3 1 0 0 1 1 1 1 Phosphorylase superfamily NAD_binding_2 PF03446.10 KKK17438.1 - 3.7e-28 98.4 0.1 7.7e-28 97.3 0.0 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.13 KKK17438.1 - 2.3e-05 24.1 1.6 3.4e-05 23.5 0.2 1.8 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 KKK17438.1 - 0.0017 18.0 0.2 0.0037 16.9 0.1 1.5 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 2-Hacid_dh_C PF02826.14 KKK17438.1 - 0.0025 16.9 0.0 0.0048 16.0 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.12 KKK17438.1 - 0.0026 18.1 0.3 0.01 16.2 0.0 2.1 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent UDPG_MGDP_dh_N PF03721.9 KKK17438.1 - 0.0027 17.1 0.1 0.0056 16.0 0.1 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox PF00070.22 KKK17438.1 - 0.0054 17.1 0.1 0.015 15.6 0.1 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 KKK17438.1 - 0.025 14.0 0.2 0.045 13.1 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DUF2235 PF09994.4 KKK17439.1 - 3.6e-93 311.9 0.0 5e-93 311.4 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Abhydrolase_5 PF12695.2 KKK17441.1 - 1.2e-07 31.5 0.0 2.1e-07 30.7 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KKK17441.1 - 9.5e-07 28.9 0.2 5.3e-06 26.4 0.1 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF4599 PF15371.1 KKK17441.1 - 0.088 12.8 0.0 0.23 11.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4599) DUF3336 PF11815.3 KKK17442.1 - 5.7e-46 155.6 1.0 9.1e-46 154.9 0.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 KKK17442.1 - 5.2e-22 78.7 0.0 9.4e-22 77.9 0.0 1.4 1 0 0 1 1 1 1 Patatin-like phospholipase SKG6 PF08693.5 KKK17443.1 - 0.00068 18.8 0.6 0.0013 18.0 0.4 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Syndecan PF01034.15 KKK17443.1 - 0.0014 18.2 0.2 0.0029 17.1 0.1 1.5 1 0 0 1 1 1 1 Syndecan domain Mid2 PF04478.7 KKK17443.1 - 0.0037 16.6 0.0 0.0075 15.6 0.0 1.5 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor DEPP PF15343.1 KKK17443.1 - 0.0037 16.9 3.5 0.015 14.8 1.6 2.1 2 0 0 2 2 2 1 Decidual protein induced by progesterone family EphA2_TM PF14575.1 KKK17443.1 - 0.049 14.0 0.6 0.17 12.2 0.1 2.1 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain CD99L2 PF12301.3 KKK17443.1 - 0.054 13.1 0.1 0.2 11.3 0.0 1.9 2 0 0 2 2 2 0 CD99 antigen like protein 2 Protocadherin PF08374.6 KKK17443.1 - 0.056 13.0 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 Protocadherin CD34_antigen PF06365.7 KKK17443.1 - 0.056 13.0 0.0 0.096 12.3 0.0 1.3 1 0 0 1 1 1 0 CD34/Podocalyxin family EssA PF10661.4 KKK17443.1 - 0.069 12.8 0.3 0.13 11.9 0.1 1.5 2 0 0 2 2 2 0 WXG100 protein secretion system (Wss), protein EssA DUF2633 PF11119.3 KKK17443.1 - 0.13 11.9 1.0 0.28 10.9 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2633) ETRAMP PF09716.5 KKK17443.1 - 0.14 12.1 0.0 0.35 10.8 0.0 1.6 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) RCR PF12273.3 KKK17445.1 - 0.0022 18.5 2.8 0.0065 17.0 2.0 1.7 1 1 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red EphA2_TM PF14575.1 KKK17445.1 - 0.15 12.4 0.0 0.34 11.3 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF912 PF06024.7 KKK17445.1 - 0.17 11.9 0.0 0.29 11.2 0.0 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) FAM163 PF15069.1 KKK17445.1 - 0.21 12.1 3.5 1.2 9.7 0.1 3.2 4 0 0 4 4 4 0 FAM163 family AA_permease PF00324.16 KKK17446.1 - 9.5e-127 423.2 46.6 1.2e-126 422.9 32.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KKK17446.1 - 1.1e-30 106.5 51.9 1.4e-30 106.2 36.0 1.1 1 0 0 1 1 1 1 Amino acid permease Aldedh PF00171.17 KKK17447.1 - 3.7e-109 365.1 0.1 4.5e-109 364.8 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF4322 PF14210.1 KKK17447.1 - 0.18 11.2 0.1 1.5 8.3 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4322) HECT PF00632.20 KKK17448.1 - 8.3e-84 281.4 0.0 1.4e-83 280.6 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) HEAT PF02985.17 KKK17448.1 - 0.00029 20.6 1.1 0.074 13.1 0.0 4.4 4 0 0 4 4 4 1 HEAT repeat Arm PF00514.18 KKK17448.1 - 0.0022 17.7 2.2 2.4 8.1 0.0 5.5 5 1 1 6 6 6 1 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.15 KKK17448.1 - 0.18 10.0 4.2 0.19 9.9 0.1 2.6 3 0 0 3 3 3 0 Adaptin N terminal region Pkinase PF00069.20 KKK17449.1 - 2.4e-08 33.4 0.1 3.7e-07 29.5 0.1 2.1 1 1 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 KKK17449.1 - 0.047 12.6 0.0 0.061 12.2 0.0 1.2 1 0 0 1 1 1 0 Kinase-like MutS_V PF00488.16 KKK17450.1 - 1.2e-80 270.2 0.0 2e-80 269.6 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 KKK17450.1 - 2.7e-53 180.8 0.1 5.1e-53 179.9 0.0 1.5 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 KKK17450.1 - 4.3e-33 113.7 0.0 1.5e-32 111.9 0.0 1.9 2 0 0 2 2 2 1 MutS domain I MutS_II PF05188.12 KKK17450.1 - 1.7e-14 54.0 0.0 6.8e-14 52.0 0.0 2.1 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.13 KKK17450.1 - 1.8e-12 47.2 0.2 4e-12 46.1 0.1 1.6 1 0 0 1 1 1 1 MutS family domain IV AAA_29 PF13555.1 KKK17450.1 - 0.044 13.3 0.0 0.096 12.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_21 PF13304.1 KKK17450.1 - 0.15 12.0 0.2 0.5 10.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain tRNA-synt_1b PF00579.20 KKK17451.1 - 3.7e-67 226.5 0.1 2.6e-58 197.4 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (W and Y) tRNA-synt_2 PF00152.15 KKK17452.1 - 1.1e-106 356.3 0.0 3.1e-106 354.9 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.20 KKK17452.1 - 0.00036 20.1 0.4 0.0021 17.6 0.1 2.3 2 1 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA_anti-codon PF01336.20 KKK17452.1 - 0.0026 17.5 0.0 0.0057 16.4 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain UbiA PF01040.13 KKK17453.1 - 4.3e-31 108.0 19.9 6.3e-31 107.5 13.8 1.3 1 0 0 1 1 1 1 UbiA prenyltransferase family ORC6 PF05460.8 KKK17454.1 - 0.47 9.4 5.5 0.62 9.1 3.8 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) PQ-loop PF04193.9 KKK17455.1 - 2e-19 68.8 4.6 4.6e-10 38.9 0.9 2.7 2 0 0 2 2 2 2 PQ loop repeat Med8 PF10232.4 KKK17456.1 - 9.8e-31 107.0 8.0 1.5e-20 73.7 1.7 2.1 1 1 1 2 2 2 2 Mediator of RNA polymerase II transcription complex subunit 8 CENP-B_dimeris PF09026.5 KKK17456.1 - 0.00011 22.3 6.7 0.00022 21.4 4.7 1.5 1 0 0 1 1 1 1 Centromere protein B dimerisation domain Myc_N PF01056.13 KKK17456.1 - 0.00018 20.7 3.0 0.00018 20.7 2.1 1.8 2 0 0 2 2 2 1 Myc amino-terminal region Daxx PF03344.10 KKK17456.1 - 0.0042 15.6 6.7 0.0054 15.2 4.6 1.4 1 0 0 1 1 1 1 Daxx Family BSP_II PF05432.6 KKK17456.1 - 0.0051 16.1 9.5 0.0088 15.3 6.6 1.4 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) Nop14 PF04147.7 KKK17456.1 - 0.0092 13.9 8.7 0.0098 13.8 6.1 1.1 1 0 0 1 1 1 1 Nop14-like family Nucleoplasmin PF03066.10 KKK17456.1 - 0.036 13.5 10.4 0.062 12.8 7.2 1.4 1 0 0 1 1 1 0 Nucleoplasmin DNA_gyraseB PF00204.20 KKK17456.1 - 0.072 12.3 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 DNA gyrase B VID27 PF08553.5 KKK17456.1 - 0.94 7.6 5.3 1.2 7.2 3.7 1.2 1 0 0 1 1 1 0 VID27 cytoplasmic protein NOA36 PF06524.7 KKK17456.1 - 1 8.5 6.5 1.6 7.8 4.5 1.3 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.8 KKK17456.1 - 2.3 5.8 16.3 3.9 5.1 11.3 1.3 1 0 0 1 1 1 0 DNA polymerase phi DUF2457 PF10446.4 KKK17456.1 - 4.9 5.7 13.1 0.21 10.2 5.3 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) Ubie_methyltran PF01209.13 KKK17457.1 - 3e-79 265.4 0.0 6.2e-79 264.3 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.7 KKK17457.1 - 8.5e-15 55.0 0.0 6.7e-14 52.1 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KKK17457.1 - 3.7e-14 52.5 0.0 2.1e-13 50.1 0.0 2.1 3 0 0 3 3 3 1 Methyltransferase domain SIS PF01380.17 KKK17457.1 - 4.7e-13 48.8 0.1 3e-12 46.2 0.0 2.3 2 1 0 2 2 2 1 SIS domain Methyltransf_23 PF13489.1 KKK17457.1 - 1.2e-09 38.1 0.0 3.3e-09 36.6 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 KKK17457.1 - 6.2e-09 36.2 0.0 1.7e-08 34.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 KKK17457.1 - 8e-08 32.5 0.0 2.8e-07 30.8 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain SIS_2 PF13580.1 KKK17457.1 - 9.1e-08 31.9 0.1 1.9e-05 24.3 0.1 2.3 1 1 1 2 2 2 2 SIS domain Methyltransf_18 PF12847.2 KKK17457.1 - 3.6e-07 30.7 0.0 1.3e-06 28.9 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 KKK17457.1 - 4.2e-05 23.5 0.0 0.00019 21.4 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_8 PF05148.10 KKK17457.1 - 0.26 10.8 0.0 0.56 9.8 0.0 1.5 1 0 0 1 1 1 0 Hypothetical methyltransferase CTP_transf_2 PF01467.21 KKK17458.1 - 5.4e-29 101.2 0.0 6.8e-29 100.9 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase Peptidase_C13 PF01650.13 KKK17458.1 - 0.14 11.4 0.0 0.22 10.7 0.0 1.2 1 0 0 1 1 1 0 Peptidase C13 family Fungal_trans PF04082.13 KKK17459.1 - 2.3e-26 92.2 0.0 4.1e-26 91.4 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK17459.1 - 3.5e-06 26.8 9.4 7e-06 25.8 6.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BUD22 PF09073.5 KKK17460.1 - 3.1e-110 369.2 24.5 3.5e-110 369.0 17.0 1.0 1 0 0 1 1 1 1 BUD22 Pro_dh PF01619.13 KKK17461.1 - 4.6e-33 114.5 0.3 5.8e-33 114.2 0.2 1.1 1 0 0 1 1 1 1 Proline dehydrogenase OCD_Mu_crystall PF02423.10 KKK17462.1 - 7.5e-13 47.9 0.0 2.4e-12 46.2 0.0 1.7 1 1 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.15 KKK17462.1 - 0.0017 18.4 0.0 0.0057 16.7 0.0 1.8 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Glyco_tran_WecB PF03808.8 KKK17462.1 - 0.087 12.2 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family Proteasome_A_N PF10584.4 KKK17462.1 - 0.098 12.0 0.0 0.19 11.0 0.0 1.5 1 0 0 1 1 1 0 Proteasome subunit A N-terminal signature E1_dh PF00676.15 KKK17463.1 - 3.4e-86 288.6 0.0 4.1e-86 288.3 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.16 KKK17463.1 - 0.00012 21.6 0.0 0.0017 17.9 0.0 2.2 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain XFP_N PF09364.5 KKK17463.1 - 0.0067 15.0 0.0 0.014 14.0 0.0 1.4 1 0 0 1 1 1 1 XFP N-terminal domain DXP_synthase_N PF13292.1 KKK17463.1 - 0.086 11.7 0.0 0.81 8.5 0.0 2.2 2 0 0 2 2 2 0 1-deoxy-D-xylulose-5-phosphate synthase Elongin_A PF06881.6 KKK17463.1 - 0.11 12.9 3.7 0.55 10.6 3.2 1.6 2 0 0 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A Glyco_hydro_2 PF00703.16 KKK17464.1 - 3.5e-05 24.2 0.0 9.3e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Glyco_hydro_2_C PF02836.12 KKK17464.1 - 0.018 13.9 0.0 0.033 13.1 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain DUF4299 PF14132.1 KKK17464.1 - 0.078 12.1 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4299) Complex1_30kDa PF00329.14 KKK17465.1 - 5.2e-36 123.0 0.0 7.5e-36 122.4 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit zf-RING_4 PF14570.1 KKK17466.1 - 6.5e-19 67.2 13.4 1.1e-18 66.4 9.3 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain RRM_1 PF00076.17 KKK17466.1 - 4.4e-05 23.0 0.0 0.00011 21.8 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_3 PF13920.1 KKK17466.1 - 8.6e-05 22.1 6.9 0.00015 21.3 4.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Baculo_IE-1 PF05290.6 KKK17466.1 - 0.00097 18.8 5.1 0.0018 18.0 3.5 1.4 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) RRM_5 PF13893.1 KKK17466.1 - 0.0019 17.9 0.0 0.0041 16.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_bind PF08675.6 KKK17466.1 - 0.086 12.8 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 RNA binding domain zf-C3HC4 PF00097.20 KKK17466.1 - 0.21 11.2 12.7 0.39 10.4 8.8 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KKK17466.1 - 1.4 9.0 11.9 2.4 8.2 8.2 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) NAD_binding_8 PF13450.1 KKK17467.1 - 3.8e-09 36.4 0.0 8.5e-09 35.3 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 KKK17467.1 - 0.00012 21.3 0.0 0.00047 19.3 0.0 1.8 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.1 KKK17467.1 - 0.00053 20.1 0.1 0.0013 18.8 0.1 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KKK17467.1 - 0.017 14.9 0.0 0.08 12.8 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KKK17467.1 - 0.021 13.8 0.0 0.029 13.4 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase DAO PF01266.19 KKK17467.1 - 0.022 13.6 0.0 0.032 13.1 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 KKK17467.1 - 0.03 13.3 0.0 0.049 12.6 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.1 KKK17467.1 - 0.066 12.9 0.1 0.95 9.2 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding Thi4 PF01946.12 KKK17467.1 - 0.1 11.6 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.9 KKK17467.1 - 0.13 10.6 0.0 0.18 10.2 0.0 1.1 1 0 0 1 1 1 0 HI0933-like protein Aldedh PF00171.17 KKK17468.1 - 8.7e-169 561.7 3.1 3.2e-158 526.8 0.5 2.0 1 1 1 2 2 2 2 Aldehyde dehydrogenase family HATPase_c PF02518.21 KKK17469.1 - 4e-30 103.7 0.0 1.7e-29 101.8 0.0 2.2 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 KKK17469.1 - 1.3e-22 79.8 0.9 4.1e-21 75.0 0.0 2.8 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.20 KKK17469.1 - 2.7e-20 72.1 0.0 9.3e-20 70.4 0.0 2.1 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain AAA_16 PF13191.1 KKK17469.1 - 1.7e-12 47.7 0.5 2.4e-11 43.9 0.0 3.1 3 0 0 3 3 3 1 AAA ATPase domain GAF_2 PF13185.1 KKK17469.1 - 6.8e-12 46.0 0.2 2.4e-11 44.3 0.0 2.1 2 0 0 2 2 2 1 GAF domain Pkinase PF00069.20 KKK17469.1 - 7.1e-08 31.9 0.0 5.6e-07 28.9 0.0 2.3 2 0 0 2 2 2 1 Protein kinase domain GAF_3 PF13492.1 KKK17469.1 - 1.8e-07 31.3 0.2 2.1e-06 27.8 0.0 2.9 3 0 0 3 3 3 1 GAF domain GAF PF01590.21 KKK17469.1 - 1.9e-07 31.2 0.0 3.3e-06 27.3 0.0 2.7 2 0 0 2 2 2 1 GAF domain TPR_12 PF13424.1 KKK17469.1 - 3e-06 27.0 3.7 0.062 13.2 0.0 4.9 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.1 KKK17469.1 - 7.1e-05 22.3 0.0 0.071 12.9 0.0 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat AAA_22 PF13401.1 KKK17469.1 - 0.0011 19.1 0.1 2 8.5 0.0 3.6 3 0 0 3 3 2 1 AAA domain NB-ARC PF00931.17 KKK17469.1 - 0.0013 17.6 0.0 1.3 7.7 0.0 2.7 3 0 0 3 3 3 2 NB-ARC domain TPR_11 PF13414.1 KKK17469.1 - 0.0024 17.4 2.1 2.1 8.0 0.0 5.2 5 1 1 6 6 6 1 TPR repeat TPR_2 PF07719.12 KKK17469.1 - 0.016 15.0 0.0 52 4.1 0.0 4.4 3 0 0 3 3 3 0 Tetratricopeptide repeat HATPase_c_3 PF13589.1 KKK17469.1 - 0.018 14.7 0.0 0.037 13.6 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TPR_1 PF00515.23 KKK17469.1 - 0.04 13.5 0.0 21 4.9 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat NACHT PF05729.7 KKK17469.1 - 0.068 12.8 0.0 0.79 9.3 0.0 2.4 2 0 0 2 2 2 0 NACHT domain DUF258 PF03193.11 KKK17469.1 - 0.14 11.3 0.0 0.39 9.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function, DUF258 TPR_14 PF13428.1 KKK17469.1 - 0.21 12.3 7.3 7.2 7.5 0.0 5.6 4 1 1 5 5 5 0 Tetratricopeptide repeat Sugar_tr PF00083.19 KKK17470.1 - 4.1e-59 200.3 30.7 5e-59 200.0 21.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KKK17470.1 - 3.5e-19 68.7 34.8 5.1e-19 68.1 24.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Glyco_hydro_1 PF00232.13 KKK17471.1 - 2.6e-145 484.0 0.8 3.6e-145 483.6 0.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Glyco_hyd_65N_2 PF14498.1 KKK17471.1 - 3.3e-58 197.1 0.0 4.6e-58 196.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Glyco_hydro_65N PF03636.10 KKK17471.1 - 0.022 14.0 0.0 0.036 13.3 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain Allantoicase PF03561.10 KKK17472.1 - 5.6e-86 285.6 0.0 1.7e-45 154.1 0.0 2.1 2 0 0 2 2 2 2 Allantoicase repeat Cytochrome_CBB3 PF13442.1 KKK17473.1 - 0.038 14.1 0.0 0.051 13.7 0.0 1.3 1 0 0 1 1 1 0 Cytochrome C oxidase, cbb3-type, subunit III DNA_pol_A PF00476.15 KKK17473.1 - 0.039 12.5 0.0 0.043 12.4 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase family A Fungal_trans_2 PF11951.3 KKK17474.1 - 2.7e-21 75.6 0.1 2.2e-16 59.4 0.1 2.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK17474.1 - 3.3e-06 26.8 6.7 6.2e-06 26.0 4.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RRF_GI PF12614.3 KKK17474.1 - 0.13 12.1 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 Ribosome recycling factor Pkinase PF00069.20 KKK17475.1 - 1.4e-64 217.7 0.0 2.1e-64 217.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK17475.1 - 1.8e-31 109.1 0.0 4.2e-31 107.9 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KKK17475.1 - 0.00031 19.8 0.0 0.00065 18.7 0.0 1.6 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KKK17475.1 - 0.0022 17.0 0.0 0.0038 16.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KKK17475.1 - 0.043 13.5 0.1 0.17 11.5 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.17 KKK17475.1 - 0.049 12.9 0.0 0.087 12.1 0.0 1.4 1 0 0 1 1 1 0 RIO1 family tRNA-synt_2b PF00587.20 KKK17476.1 - 2.6e-21 75.9 0.0 3.6e-21 75.5 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 KKK17476.1 - 1.6e-12 47.3 5.0 2.7e-12 46.6 3.5 1.3 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain GOLGA2L5 PF15070.1 KKK17476.1 - 0.0068 14.9 4.9 0.0096 14.4 3.4 1.1 1 0 0 1 1 1 1 Putative golgin subfamily A member 2-like protein 5 CENP-F_leu_zip PF10473.4 KKK17476.1 - 0.013 15.3 6.3 0.024 14.4 4.0 1.7 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Atg14 PF10186.4 KKK17476.1 - 0.017 14.0 3.8 0.029 13.3 2.6 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF4140 PF13600.1 KKK17476.1 - 0.018 15.4 0.5 0.018 15.4 0.4 2.4 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) ING PF12998.2 KKK17476.1 - 0.024 14.9 6.4 0.044 14.0 4.4 1.3 1 0 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding HAUS-augmin3 PF14932.1 KKK17476.1 - 0.026 13.6 4.3 0.039 13.1 3.0 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 Spc7 PF08317.6 KKK17476.1 - 0.055 12.1 5.6 0.083 11.5 3.9 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein ATG16 PF08614.6 KKK17476.1 - 0.067 13.0 6.6 0.12 12.1 4.6 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) IncA PF04156.9 KKK17476.1 - 0.078 12.5 8.0 0.13 11.8 5.5 1.2 1 0 0 1 1 1 0 IncA protein FUSC PF04632.7 KKK17476.1 - 0.084 11.2 1.5 0.12 10.8 1.0 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family TMCO5 PF14992.1 KKK17476.1 - 0.11 11.6 2.0 0.16 11.0 1.4 1.1 1 0 0 1 1 1 0 TMCO5 family DUF2968 PF11180.3 KKK17476.1 - 0.21 10.9 9.3 0.4 10.0 6.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) APG6 PF04111.7 KKK17476.1 - 0.31 10.0 4.8 0.5 9.3 3.3 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF342 PF03961.8 KKK17476.1 - 0.48 8.7 4.2 0.74 8.1 2.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) TMF_DNA_bd PF12329.3 KKK17476.1 - 0.57 10.0 11.1 1.2 9.0 6.0 2.2 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Mnd1 PF03962.10 KKK17476.1 - 1.1 8.8 6.0 2 8.0 4.1 1.3 1 0 0 1 1 1 0 Mnd1 family DUF904 PF06005.7 KKK17476.1 - 2.5 8.4 7.7 6.1 7.2 5.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF904) DivIC PF04977.10 KKK17476.1 - 4.9 6.7 9.6 12 5.4 2.3 2.5 1 1 1 2 2 2 0 Septum formation initiator BTB PF00651.26 KKK17477.1 - 0.19 11.7 0.0 0.61 10.0 0.0 1.8 2 0 0 2 2 2 0 BTB/POZ domain DUF4267 PF14087.1 KKK17481.1 - 2.7e-32 110.6 3.8 5.3e-32 109.7 2.7 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) adh_short PF00106.20 KKK17481.1 - 8e-11 42.1 0.7 1.6e-10 41.1 0.1 1.7 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 KKK17481.1 - 0.00027 20.7 0.0 0.00039 20.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KKK17481.1 - 0.0037 16.7 0.0 0.0072 15.7 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Peroxidase_2 PF01328.12 KKK17482.1 - 6.2e-43 146.6 0.0 8.2e-43 146.2 0.0 1.0 1 0 0 1 1 1 1 Peroxidase, family 2 p450 PF00067.17 KKK17483.1 - 2.6e-56 191.0 0.0 3.6e-56 190.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 KKK17484.1 - 2e-53 181.5 0.0 2.9e-53 181.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 ketoacyl-synt PF00109.21 KKK17485.1 - 2.3e-78 263.1 0.0 4.8e-78 262.1 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 KKK17485.1 - 4.3e-44 151.1 0.0 1.1e-41 143.2 0.0 2.7 2 1 0 2 2 2 1 Acyl transferase domain Thioesterase PF00975.15 KKK17485.1 - 2.7e-36 125.9 0.0 9.1e-36 124.2 0.0 1.9 2 0 0 2 2 2 1 Thioesterase domain Ketoacyl-synt_C PF02801.17 KKK17485.1 - 2.2e-33 114.6 0.1 5.3e-33 113.3 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.20 KKK17485.1 - 1.4e-19 70.0 11.0 2.8e-11 43.4 0.5 2.9 3 0 0 3 3 2 2 Phosphopantetheine attachment site PS-DH PF14765.1 KKK17485.1 - 5.6e-15 55.2 0.0 1e-14 54.3 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase Abhydrolase_6 PF12697.2 KKK17485.1 - 1.9e-07 31.2 0.0 0.0023 17.8 0.0 3.2 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KKK17485.1 - 3.1e-06 26.9 0.0 0.016 14.9 0.0 2.9 3 0 0 3 3 3 2 Alpha/beta hydrolase family Thiolase_N PF00108.18 KKK17485.1 - 0.0016 17.4 0.0 0.0034 16.4 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Lipase_3 PF01764.20 KKK17485.1 - 0.16 11.6 0.0 21 4.6 0.0 2.5 2 0 0 2 2 2 0 Lipase (class 3) BSP_II PF05432.6 KKK17485.1 - 0.54 9.4 4.2 1 8.5 2.9 1.3 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) MFS_1 PF07690.11 KKK17486.1 - 7.3e-13 47.9 14.4 9.5e-13 47.5 10.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF4267 PF14087.1 KKK17486.1 - 0.029 13.9 0.1 0.029 13.9 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4267) CVNH PF08881.5 KKK17488.1 - 3.5e-31 107.5 0.9 4.9e-31 107.0 0.6 1.2 1 0 0 1 1 1 1 CVNH domain Rick_17kDa_Anti PF05433.10 KKK17488.1 - 7.5e-06 25.5 13.9 1.2e-05 24.9 9.6 1.3 1 0 0 1 1 1 1 Glycine zipper 2TM domain Gly-zipper_OmpA PF13436.1 KKK17488.1 - 0.00066 19.3 0.0 0.001 18.6 0.0 1.4 1 0 0 1 1 1 1 Glycine-zipper containing OmpA-like membrane domain TraT PF05818.7 KKK17488.1 - 0.00097 18.6 0.0 0.0015 18.0 0.0 1.2 1 0 0 1 1 1 1 Enterobacterial TraT complement resistance protein DUF2076 PF09849.4 KKK17488.1 - 0.0024 17.9 0.4 0.0034 17.4 0.3 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) Gly-zipper_Omp PF13488.1 KKK17488.1 - 0.0024 17.4 9.5 0.004 16.7 6.6 1.3 1 0 0 1 1 1 1 Glycine zipper DUF533 PF04391.7 KKK17488.1 - 0.005 16.2 0.1 0.0074 15.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF533) Gly-zipper_YMGG PF13441.1 KKK17488.1 - 0.1 12.1 13.4 0.17 11.4 9.3 1.3 1 0 0 1 1 1 0 YMGG-like Gly-zipper FAP PF07174.6 KKK17488.1 - 0.19 11.0 7.4 0.27 10.5 5.1 1.2 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) Transgly_assoc PF04226.8 KKK17488.1 - 0.83 9.7 10.4 1.3 9.1 7.2 1.3 1 0 0 1 1 1 0 Transglycosylase associated protein DUF2370 PF10176.4 KKK17488.1 - 1.9 7.7 4.5 1.5 8.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2370) Pyr_redox_3 PF13738.1 KKK17489.1 - 7.2e-22 78.4 0.0 1.4e-21 77.4 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KKK17489.1 - 8e-16 57.3 0.0 3.8e-14 51.8 0.0 2.4 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 KKK17489.1 - 7.2e-09 35.5 0.2 3.4e-08 33.3 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 KKK17489.1 - 2e-06 27.0 0.0 8.5e-05 21.6 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 KKK17489.1 - 0.039 13.7 0.6 0.83 9.4 0.0 3.1 3 1 0 3 3 3 0 FAD-NAD(P)-binding mRNA_cap_C PF03919.10 KKK17489.1 - 0.046 14.0 0.1 0.11 12.8 0.1 1.6 1 0 0 1 1 1 0 mRNA capping enzyme, C-terminal domain Thi4 PF01946.12 KKK17489.1 - 0.1 11.6 0.0 0.28 10.2 0.0 1.6 2 0 0 2 2 2 0 Thi4 family DAO PF01266.19 KKK17489.1 - 0.12 11.2 0.0 0.39 9.5 0.0 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase DUF877 PF05943.7 KKK17489.1 - 0.14 10.6 0.1 0.21 10.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF877) Aldo_ket_red PF00248.16 KKK17490.1 - 3.5e-63 213.0 0.0 4.4e-63 212.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family adh_short PF00106.20 KKK17491.1 - 8.8e-36 123.3 1.2 1.2e-35 122.8 0.8 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KKK17491.1 - 1.5e-27 96.9 0.0 1.8e-27 96.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KKK17491.1 - 1.1e-18 67.5 0.7 1.7e-18 66.9 0.5 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KKK17491.1 - 2.4e-05 23.8 0.2 3.2e-05 23.4 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 KKK17491.1 - 0.0014 18.3 0.4 0.0027 17.4 0.3 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Methyltransf_18 PF12847.2 KKK17491.1 - 0.0017 18.9 0.1 0.0032 18.0 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain THF_DHG_CYH_C PF02882.14 KKK17491.1 - 0.015 14.3 0.2 0.063 12.3 0.0 1.9 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3Beta_HSD PF01073.14 KKK17491.1 - 0.056 12.1 0.2 0.081 11.6 0.2 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family 2-Hacid_dh_C PF02826.14 KKK17491.1 - 0.075 12.1 0.2 0.14 11.2 0.2 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF374 PF04028.8 KKK17491.1 - 0.081 12.1 0.0 0.37 10.0 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF374) Shikimate_DH PF01488.15 KKK17491.1 - 0.12 12.4 1.5 0.25 11.4 1.1 1.6 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase EthD PF07110.6 KKK17492.1 - 2.1e-16 60.6 0.2 3.5e-16 59.9 0.1 1.4 1 0 0 1 1 1 1 EthD domain GST_C PF00043.20 KKK17492.1 - 4.3e-13 49.0 0.0 7.4e-13 48.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 KKK17492.1 - 4e-10 39.7 0.0 1.3e-09 38.0 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 KKK17492.1 - 8.2e-09 35.5 0.0 3.7e-08 33.4 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KKK17492.1 - 1.6e-06 27.9 0.1 1.1e-05 25.3 0.0 2.4 2 1 1 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 KKK17492.1 - 1.7e-06 28.3 0.0 3.8e-06 27.2 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KKK17492.1 - 4.9e-06 26.3 0.0 1.2e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Pkinase PF00069.20 KKK17508.1 - 3.2e-71 239.5 0.0 4.4e-71 239.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK17508.1 - 1.2e-30 106.5 0.0 1.7e-30 105.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 KKK17508.1 - 1.4e-14 54.3 2.1 1.4e-14 54.3 1.5 2.8 2 0 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.1 KKK17508.1 - 3.7e-09 35.9 0.0 6.9e-09 35.0 0.0 1.4 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 KKK17508.1 - 0.0059 16.3 0.0 0.01 15.5 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 KKK17508.1 - 0.054 12.8 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Choline_kinase PF01633.15 KKK17508.1 - 0.07 12.7 0.1 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.9 KKK17508.1 - 0.12 11.3 0.1 0.21 10.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family F-box-like PF12937.2 KKK17509.1 - 0.009 15.7 0.1 0.024 14.3 0.1 1.8 1 0 0 1 1 1 1 F-box-like DUF4027 PF13219.1 KKK17509.1 - 0.033 13.6 0.0 0.063 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4027) AAA PF00004.24 KKK17510.1 - 1.2e-40 138.7 0.0 2.4e-40 137.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 KKK17510.1 - 3.4e-05 23.0 0.1 0.00011 21.2 0.0 1.9 3 0 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 KKK17510.1 - 0.00012 21.7 1.4 0.00031 20.4 0.0 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KKK17510.1 - 0.00036 20.5 0.3 0.017 15.1 0.0 2.8 2 1 1 3 3 3 1 AAA ATPase domain AAA_2 PF07724.9 KKK17510.1 - 0.00072 19.5 1.7 0.0097 15.8 0.0 3.4 3 1 0 3 3 3 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 KKK17510.1 - 0.0028 16.6 0.0 0.0074 15.2 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_22 PF13401.1 KKK17510.1 - 0.0033 17.5 1.7 0.031 14.4 0.1 2.7 2 1 0 2 2 1 1 AAA domain PhoH PF02562.11 KKK17510.1 - 0.0053 16.0 0.2 0.052 12.7 0.1 2.2 2 0 0 2 2 2 1 PhoH-like protein Mg_chelatase PF01078.16 KKK17510.1 - 0.01 15.0 0.1 0.032 13.3 0.0 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 KKK17510.1 - 0.011 15.6 0.0 0.032 14.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 KKK17510.1 - 0.012 15.3 0.3 0.031 14.0 0.2 1.6 1 0 0 1 1 1 0 Part of AAA domain Zeta_toxin PF06414.7 KKK17510.1 - 0.022 13.8 1.0 0.1 11.6 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin IstB_IS21 PF01695.12 KKK17510.1 - 0.023 14.0 0.1 0.049 13.0 0.1 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_14 PF13173.1 KKK17510.1 - 0.026 14.4 0.0 0.25 11.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 KKK17510.1 - 0.042 13.2 0.9 0.5 9.7 0.1 2.4 1 1 1 2 2 2 0 AAA domain AAA_24 PF13479.1 KKK17510.1 - 0.048 13.2 0.1 0.14 11.7 0.1 1.8 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 KKK17510.1 - 0.048 14.4 0.1 0.048 14.4 0.1 2.9 2 2 0 2 2 2 0 AAA domain AAA_11 PF13086.1 KKK17510.1 - 0.46 10.0 4.5 0.84 9.1 0.0 2.5 2 1 0 2 2 2 0 AAA domain DUF496 PF04363.7 KKK17510.1 - 0.96 9.3 9.5 0.47 10.3 0.6 3.2 2 1 1 3 3 2 0 Protein of unknown function (DUF496) PGM_PMM_II PF02879.11 KKK17511.1 - 3.3e-16 59.4 0.2 1.4e-15 57.4 0.1 2.2 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_I PF02878.11 KKK17511.1 - 3.8e-15 55.5 0.2 1.7e-06 27.5 0.0 2.9 1 1 1 2 2 2 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.15 KKK17511.1 - 1.4e-10 41.0 0.9 4.5e-10 39.3 0.2 2.1 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.11 KKK17511.1 - 0.03 14.3 0.1 0.11 12.5 0.1 2.0 1 1 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III DEAD PF00270.24 KKK17512.1 - 2.1e-44 150.9 0.0 4.3e-44 149.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KKK17512.1 - 1.6e-25 88.7 0.0 3.8e-25 87.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KKK17512.1 - 0.0042 16.9 0.0 0.009 15.8 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Methyltransf_31 PF13847.1 KKK17513.1 - 6.1e-15 55.1 0.0 1e-14 54.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 KKK17513.1 - 2.7e-11 43.1 0.0 4.1e-11 42.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 KKK17513.1 - 4.3e-11 43.3 0.0 1.2e-10 41.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 KKK17513.1 - 1.1e-10 41.5 0.0 3.1e-10 40.1 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 KKK17513.1 - 2.6e-09 37.4 0.0 7.2e-09 36.0 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain PRMT5 PF05185.11 KKK17513.1 - 1.3e-08 34.2 0.0 1.6e-08 33.8 0.0 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_25 PF13649.1 KKK17513.1 - 7e-07 29.5 0.0 2.7e-06 27.6 0.0 2.0 2 0 0 2 2 1 1 Methyltransferase domain MTS PF05175.9 KKK17513.1 - 9.4e-07 28.3 0.1 3e-06 26.6 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_23 PF13489.1 KKK17513.1 - 1.3e-06 28.1 0.0 4.1e-06 26.6 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 KKK17513.1 - 1.9e-06 28.2 0.0 3.9e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 KKK17513.1 - 1.4e-05 24.0 0.0 2e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) CMAS PF02353.15 KKK17513.1 - 2.9e-05 23.2 0.0 4.2e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase FtsJ PF01728.14 KKK17513.1 - 0.00027 20.9 0.0 0.00093 19.2 0.0 1.7 2 0 0 2 2 2 1 FtsJ-like methyltransferase Ubie_methyltran PF01209.13 KKK17513.1 - 0.00034 19.8 0.0 0.00053 19.1 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.1 KKK17513.1 - 0.0015 18.2 0.0 0.0027 17.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 KKK17513.1 - 0.0038 16.7 0.0 0.0057 16.1 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_4 PF02390.12 KKK17513.1 - 0.0058 15.7 0.0 0.01 14.9 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase PCMT PF01135.14 KKK17513.1 - 0.019 14.5 0.1 0.031 13.7 0.1 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) UPF0020 PF01170.13 KKK17513.1 - 0.05 13.1 0.0 0.087 12.3 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Met_10 PF02475.11 KKK17513.1 - 0.061 12.9 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_24 PF13578.1 KKK17513.1 - 0.062 14.1 0.0 0.18 12.6 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain TehB PF03848.9 KKK17513.1 - 0.066 12.3 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 Tellurite resistance protein TehB Rsm22 PF09243.5 KKK17513.1 - 0.083 11.9 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial small ribosomal subunit Rsm22 DOT1 PF08123.8 KKK17513.1 - 0.086 12.1 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 PCI PF01399.22 KKK17514.1 - 1.8e-21 76.4 0.0 1.2e-20 73.7 0.1 2.3 2 1 0 2 2 2 1 PCI domain DDRGK PF09756.4 KKK17514.1 - 7.2e-05 22.2 0.1 7.2e-05 22.2 0.1 1.7 2 0 0 2 2 2 1 DDRGK domain HTH_Crp_2 PF13545.1 KKK17514.1 - 0.019 14.7 0.1 1.3 8.9 0.1 3.0 2 1 1 3 3 3 0 Crp-like helix-turn-helix domain Prefoldin_2 PF01920.15 KKK17514.1 - 0.044 13.5 2.5 0.082 12.6 0.4 2.5 2 0 0 2 2 2 0 Prefoldin subunit TPR_8 PF13181.1 KKK17514.1 - 0.28 11.0 10.7 9.8 6.2 0.0 5.2 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.1 KKK17514.1 - 2.3 9.0 13.7 12 6.8 0.2 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_12 PF13424.1 KKK17514.1 - 4 7.4 20.2 0.9 9.5 2.3 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat SWIB PF02201.13 KKK17515.1 - 9e-16 57.3 0.0 1.5e-15 56.5 0.0 1.4 1 0 0 1 1 1 1 SWIB/MDM2 domain MAGE PF01454.14 KKK17516.1 - 1.8e-15 56.8 0.1 2.4e-15 56.3 0.1 1.2 1 0 0 1 1 1 1 MAGE family Ribosomal_L27e PF01777.13 KKK17517.1 - 5.1e-39 132.2 2.6 6.7e-39 131.9 1.8 1.1 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.24 KKK17517.1 - 0.00015 21.3 1.2 0.00026 20.5 0.2 2.0 2 0 0 2 2 2 1 KOW motif TRAM_LAG1_CLN8 PF03798.11 KKK17519.1 - 2.2e-50 170.9 19.0 2.2e-50 170.9 13.2 1.9 2 0 0 2 2 2 1 TLC domain Brix PF04427.13 KKK17520.1 - 1.2e-58 197.9 0.3 1.8e-58 197.3 0.2 1.3 1 0 0 1 1 1 1 Brix domain Spore_coat_CotO PF14153.1 KKK17520.1 - 6.3 6.2 21.6 6.7 6.1 0.3 2.2 2 0 0 2 2 2 0 Spore coat protein CotO Per1 PF04080.8 KKK17521.1 - 4.4e-108 360.7 15.7 5.5e-108 360.4 10.8 1.1 1 0 0 1 1 1 1 Per1-like Sof1 PF04158.9 KKK17522.1 - 2.5e-30 104.3 14.3 4.1e-30 103.6 9.9 1.4 1 0 0 1 1 1 1 Sof1-like domain WD40 PF00400.27 KKK17522.1 - 1.1e-27 94.8 0.1 4.5e-09 35.8 0.0 5.2 5 0 0 5 5 5 3 WD domain, G-beta repeat Nup160 PF11715.3 KKK17522.1 - 0.002 16.3 0.4 0.032 12.3 0.1 2.2 2 0 0 2 2 2 2 Nucleoporin Nup120/160 adh_short PF00106.20 KKK17523.1 - 2.4e-28 99.1 0.3 3.5e-28 98.6 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KKK17523.1 - 1.5e-14 54.3 0.0 2.1e-14 53.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KKK17523.1 - 7.1e-09 35.5 0.2 1.4e-08 34.6 0.2 1.4 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 KKK17523.1 - 0.00097 18.3 0.1 0.002 17.3 0.0 1.4 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) DUF690 PF05108.8 KKK17523.1 - 0.012 14.0 0.1 0.018 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF690) CoA_transf_3 PF02515.12 KKK17524.1 - 1.3e-57 194.0 0.0 2.2e-57 193.4 0.0 1.4 1 0 0 1 1 1 1 CoA-transferase family III PHD PF00628.24 KKK17524.1 - 4.4e-09 35.8 9.8 9.2e-09 34.8 6.8 1.6 1 0 0 1 1 1 1 PHD-finger C1_1 PF00130.17 KKK17524.1 - 0.0017 18.0 3.3 0.0037 16.9 2.3 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) FYVE_2 PF02318.11 KKK17524.1 - 0.005 16.7 2.7 0.0085 15.9 1.9 1.3 1 0 0 1 1 1 1 FYVE-type zinc finger Herpes_UL52 PF03121.10 KKK17524.1 - 0.078 12.7 2.8 0.15 11.7 1.9 1.4 1 0 0 1 1 1 0 Herpesviridae UL52/UL70 DNA primase Prok-RING_1 PF14446.1 KKK17524.1 - 0.19 11.4 4.7 0.4 10.4 3.2 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 PHD_2 PF13831.1 KKK17524.1 - 2.1 7.7 11.2 0.21 10.9 4.1 2.2 2 1 0 2 2 2 0 PHD-finger DTHCT PF08070.6 KKK17524.1 - 4.7 7.9 15.3 0.9 10.2 1.6 2.7 2 0 0 2 2 2 0 DTHCT (NUC029) region Lum_binding PF00677.12 KKK17525.1 - 6.7e-35 118.8 0.6 5.9e-20 70.9 0.1 2.2 2 0 0 2 2 2 2 Lumazine binding domain TauD PF02668.11 KKK17526.1 - 5e-41 141.0 1.0 6.8e-41 140.6 0.7 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family 2OG-FeII_Oxy_3 PF13640.1 KKK17526.1 - 0.00056 20.3 0.1 0.037 14.5 0.0 2.5 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DUF971 PF06155.7 KKK17526.1 - 0.024 15.0 0.0 0.042 14.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF971) Mito_carr PF00153.22 KKK17527.1 - 2.5e-65 216.2 1.6 4.8e-23 80.6 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein MS_channel PF00924.13 KKK17528.1 - 1e-22 80.5 1.9 1e-22 80.5 1.3 1.8 2 0 0 2 2 2 1 Mechanosensitive ion channel EF-hand_1 PF00036.27 KKK17528.1 - 0.00023 20.2 0.5 0.00057 19.0 0.3 1.7 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 KKK17528.1 - 0.00096 18.8 0.0 0.0025 17.5 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.1 KKK17528.1 - 0.0012 18.0 0.0 0.003 16.8 0.0 1.7 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 KKK17528.1 - 0.0014 18.7 0.2 0.0035 17.4 0.1 1.6 1 0 0 1 1 1 1 EF-hand domain pair TauD PF02668.11 KKK17529.1 - 8.6e-58 196.0 0.1 1.2e-57 195.5 0.1 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.5 KKK17529.1 - 0.0014 17.6 0.0 0.0026 16.7 0.0 1.5 1 1 0 1 1 1 1 CsiD DUF971 PF06155.7 KKK17529.1 - 0.022 15.1 0.1 0.071 13.5 0.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF971) 2OG-FeII_Oxy_3 PF13640.1 KKK17529.1 - 0.032 14.7 0.0 0.1 13.1 0.0 1.8 1 1 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily Ponericin PF07442.6 KKK17529.1 - 7.4 6.4 5.7 3.3 7.6 0.9 2.2 2 0 0 2 2 2 0 Ponericin Tubulin PF00091.20 KKK17530.1 - 9.5e-67 224.9 0.0 1.3e-66 224.5 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 KKK17530.1 - 9.6e-45 151.6 0.0 1.5e-44 151.0 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 KKK17530.1 - 0.00044 19.7 0.0 0.00081 18.8 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain adh_short PF00106.20 KKK17555.1 - 9.2e-27 93.9 0.0 1.2e-26 93.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KKK17555.1 - 2.9e-26 92.7 0.0 3.6e-26 92.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KKK17555.1 - 1.5e-08 34.5 0.0 2.2e-08 33.9 0.0 1.3 1 1 0 1 1 1 1 KR domain Trehalase PF01204.13 KKK17556.1 - 1.5e-194 647.3 0.1 1.8e-194 647.1 0.0 1.0 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.6 KKK17556.1 - 5.2e-18 64.0 0.0 8.3e-18 63.3 0.0 1.3 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain ICL PF00463.16 KKK17557.1 - 4.1e-291 965.7 4.0 4.6e-291 965.5 2.8 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 KKK17557.1 - 2.9e-12 46.3 0.1 1.2e-11 44.2 0.0 2.0 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase Aldedh PF00171.17 KKK17558.1 - 4.3e-71 239.6 0.0 5.8e-71 239.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family OTU PF02338.14 KKK17560.1 - 7.8e-18 65.2 0.5 2.1e-16 60.5 0.3 2.4 1 1 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 KKK17560.1 - 1e-07 31.5 0.0 1.6e-05 24.3 0.0 2.3 2 0 0 2 2 2 2 Peptidase C65 Otubain Gluconate_2-dh3 PF13618.1 KKK17560.1 - 5.7 7.1 7.2 0.59 10.2 0.2 2.4 2 1 1 3 3 3 0 Gluconate 2-dehydrogenase subunit 3 Malate_synthase PF01274.17 KKK17561.1 - 1.5e-36 125.4 0.0 1.7e-36 125.3 0.0 1.0 1 0 0 1 1 1 1 Malate synthase Phe_tRNA-synt_N PF02912.13 KKK17561.1 - 0.14 11.8 0.1 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 Aminoacyl tRNA synthetase class II, N-terminal domain Gln-synt_C PF00120.19 KKK17562.1 - 4.2e-62 209.6 0.0 5.3e-62 209.3 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Herpes_alk_exo PF01771.12 KKK17562.1 - 0.23 9.8 0.0 0.36 9.2 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus alkaline exonuclease Amino_oxidase PF01593.19 KKK17564.1 - 1.9e-69 234.8 1.1 2.3e-69 234.6 0.8 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KKK17564.1 - 5.7e-08 32.6 0.1 1.5e-07 31.3 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 KKK17564.1 - 9.1e-05 22.6 1.2 0.026 14.6 0.5 3.1 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KKK17564.1 - 0.0013 18.5 0.4 1.4 8.7 0.0 3.0 3 0 0 3 3 3 2 FAD-NAD(P)-binding Thi4 PF01946.12 KKK17564.1 - 0.012 14.7 0.0 0.021 13.9 0.0 1.3 1 0 0 1 1 1 0 Thi4 family DAO PF01266.19 KKK17564.1 - 0.018 13.9 5.2 0.71 8.7 0.2 3.0 3 1 0 3 3 3 0 FAD dependent oxidoreductase Pyr_redox PF00070.22 KKK17564.1 - 0.018 15.4 0.1 0.92 9.9 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KKK17564.1 - 0.019 14.0 2.5 0.038 13.0 0.2 2.5 4 0 0 4 4 4 0 FAD binding domain Pyr_redox_2 PF07992.9 KKK17564.1 - 0.038 13.8 0.0 0.075 12.8 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KKK17564.1 - 0.13 11.0 0.0 0.28 9.9 0.0 1.5 2 0 0 2 2 2 0 Glucose inhibited division protein A Shikimate_DH PF01488.15 KKK17564.1 - 0.16 12.0 0.1 0.34 11.0 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase MBOAT_2 PF13813.1 KKK17565.1 - 5.9e-20 71.1 4.9 5.9e-20 71.1 3.4 2.0 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family APT PF03440.9 KKK17565.1 - 0.2 11.3 0.9 0.71 9.6 0.1 2.1 2 0 0 2 2 2 0 Aerolysin/Pertussis toxin (APT) domain CVNH PF08881.5 KKK17566.1 - 3.2e-15 56.2 0.0 3.6e-15 56.0 0.0 1.0 1 0 0 1 1 1 1 CVNH domain TB2_DP1_HVA22 PF03134.14 KKK17568.1 - 2.5e-28 97.6 7.3 3.9e-28 97.0 5.1 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family CHCH PF06747.8 KKK17569.1 - 5.3e-07 29.3 7.4 7.4e-07 28.9 5.1 1.2 1 0 0 1 1 1 1 CHCH domain COX17 PF05051.8 KKK17569.1 - 0.013 15.4 2.0 0.018 15.0 1.4 1.2 1 0 0 1 1 1 0 Cytochrome C oxidase copper chaperone (COX17) Cmc1 PF08583.5 KKK17569.1 - 0.016 14.9 5.6 0.032 14.0 3.9 1.5 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like Toxin_25 PF08095.6 KKK17569.1 - 0.017 14.8 0.6 0.017 14.8 0.4 2.1 2 1 0 2 2 2 0 Hefutoxin family Pet191_N PF10203.4 KKK17569.1 - 0.26 11.3 3.4 0.37 10.8 2.3 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 Ndufs5 PF10200.4 KKK17569.1 - 0.43 10.6 3.4 1.6 8.7 2.3 1.7 1 1 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa BPL_N PF09825.4 KKK17570.1 - 4.2e-142 473.2 0.0 5.3e-142 472.9 0.0 1.1 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.14 KKK17570.1 - 6.5e-21 74.6 0.0 1.4e-20 73.6 0.0 1.6 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_C PF02237.12 KKK17570.1 - 0.00077 19.1 0.0 0.0022 17.6 0.0 1.8 2 0 0 2 2 2 1 Biotin protein ligase C terminal domain p450 PF00067.17 KKK17571.1 - 5.6e-33 114.1 0.0 8.1e-33 113.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 NRDE PF05742.7 KKK17572.1 - 4e-45 154.2 0.0 3.5e-40 138.0 0.0 2.0 2 0 0 2 2 2 2 NRDE protein KOW PF00467.24 KKK17574.1 - 6.2e-06 25.7 1.1 1.3e-05 24.6 0.7 1.5 1 0 0 1 1 1 1 KOW motif DUF1223 PF06764.6 KKK17574.1 - 0.12 12.1 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1223) EXS PF03124.9 KKK17575.1 - 1.7e-97 326.5 9.7 1.9e-97 326.3 6.7 1.0 1 0 0 1 1 1 1 EXS family Mucin PF01456.12 KKK17576.1 - 3.8e-06 26.7 27.5 3.8e-06 26.7 19.1 1.7 2 0 0 2 2 2 1 Mucin-like glycoprotein Dicty_REP PF05086.7 KKK17576.1 - 0.019 12.7 5.0 0.023 12.4 3.5 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein SpoIIIAH PF12685.2 KKK17576.1 - 0.16 11.4 8.2 0.33 10.4 5.7 1.4 1 0 0 1 1 1 0 SpoIIIAH-like protein TrbC PF04956.8 KKK17576.1 - 2.7 8.0 8.6 0.18 11.8 1.0 2.4 2 1 1 3 3 3 0 TrbC/VIRB2 family DUF4366 PF14283.1 KKK17576.1 - 5 6.4 6.9 7.6 5.8 3.5 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4366) AAA_14 PF13173.1 KKK17577.1 - 0.00051 19.9 0.0 0.00097 19.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KKK17577.1 - 0.0072 17.1 0.0 0.015 16.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 KKK17577.1 - 0.094 11.9 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Sigma54_activ_2 PF14532.1 KKK17577.1 - 0.11 12.5 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_19 PF13245.1 KKK17577.1 - 0.14 11.9 0.0 0.31 10.8 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain KaiC PF06745.8 KKK17577.1 - 0.17 10.9 0.0 0.26 10.3 0.0 1.2 1 0 0 1 1 1 0 KaiC AAA_16 PF13191.1 KKK17577.1 - 0.18 11.7 0.0 0.45 10.4 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain AAA_30 PF13604.1 KKK17577.1 - 0.24 10.9 0.0 0.51 9.8 0.0 1.5 1 1 0 1 1 1 0 AAA domain Pex2_Pex12 PF04757.9 KKK17578.1 - 3e-43 147.8 9.4 3.7e-43 147.5 6.5 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-RING_2 PF13639.1 KKK17578.1 - 3.2e-11 42.8 9.8 5.2e-11 42.1 6.8 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 KKK17578.1 - 5.6e-11 41.9 6.1 8.1e-11 41.4 4.3 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KKK17578.1 - 6.1e-11 42.1 9.2 1e-10 41.4 6.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KKK17578.1 - 1.4e-10 40.5 7.2 2.3e-10 39.9 5.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KKK17578.1 - 2.4e-08 33.5 7.2 4e-08 32.8 5.0 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 KKK17578.1 - 6.6e-06 25.9 8.2 1.2e-05 25.0 5.7 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 KKK17578.1 - 7.2e-06 25.6 2.2 9.8e-06 25.1 0.6 1.9 1 1 1 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.2 KKK17578.1 - 0.00027 20.9 8.0 0.00066 19.7 5.6 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_6 PF14835.1 KKK17578.1 - 0.0019 17.9 3.2 0.0034 17.1 2.2 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-Apc11 PF12861.2 KKK17578.1 - 0.054 13.3 3.7 0.11 12.2 2.6 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 KKK17578.1 - 0.054 13.0 7.4 0.1 12.2 5.1 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-Nse PF11789.3 KKK17578.1 - 0.067 12.7 3.9 0.14 11.6 2.7 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit FYVE PF01363.16 KKK17578.1 - 1.1 9.1 7.1 4.2 7.3 5.0 1.9 1 1 0 1 1 1 0 FYVE zinc finger IBR PF01485.16 KKK17578.1 - 1.4 8.8 8.2 6.2 6.7 5.7 1.9 1 1 0 1 1 1 0 IBR domain PRKCSH_1 PF13015.1 KKK17579.1 - 7.2e-33 113.2 0.6 1.1e-32 112.6 0.1 1.5 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.8 KKK17579.1 - 1.2e-10 42.0 0.1 2.7e-10 40.8 0.1 1.6 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein DUF4140 PF13600.1 KKK17579.1 - 0.071 13.5 0.1 0.12 12.7 0.1 1.4 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Cu_amine_oxid PF01179.15 KKK17580.1 - 2.7e-172 573.1 1.1 3.2e-172 572.9 0.8 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.11 KKK17580.1 - 5e-07 29.7 0.0 1.1e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Cu_amine_oxidN3 PF02728.11 KKK17580.1 - 0.00018 21.4 0.0 0.0004 20.3 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain CMAS PF02353.15 KKK17581.1 - 1.1e-62 211.6 0.1 1.4e-62 211.2 0.1 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 KKK17581.1 - 4.1e-11 42.8 0.0 9.1e-11 41.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KKK17581.1 - 8.3e-07 29.4 0.0 1.5e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KKK17581.1 - 0.00018 21.5 0.0 0.00049 20.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KKK17581.1 - 0.00095 19.6 0.0 0.0019 18.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KKK17581.1 - 0.0011 19.5 0.0 0.003 18.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KKK17581.1 - 0.0018 17.6 0.0 0.0029 17.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 KKK17581.1 - 0.006 16.9 0.0 0.015 15.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KKK17581.1 - 0.0081 15.7 0.0 0.013 15.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.8 KKK17581.1 - 0.0091 15.3 0.0 0.017 14.4 0.0 1.4 1 0 0 1 1 1 1 Histone methylation protein DOT1 N6_N4_Mtase PF01555.13 KKK17581.1 - 0.054 12.9 0.0 6.8 6.1 0.0 2.4 2 0 0 2 2 2 0 DNA methylase PCMT PF01135.14 KKK17581.1 - 0.14 11.6 0.0 0.22 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Tropomyosin_1 PF12718.2 KKK17583.1 - 1.2e-42 145.1 26.4 5e-30 104.2 11.3 2.0 2 0 0 2 2 2 2 Tropomyosin like Tropomyosin PF00261.15 KKK17583.1 - 1.8e-08 33.7 25.9 0.0017 17.4 0.7 3.0 2 1 1 3 3 3 3 Tropomyosin Mod_r PF07200.8 KKK17583.1 - 5e-06 26.4 16.2 0.0041 17.0 8.2 2.1 2 0 0 2 2 2 2 Modifier of rudimentary (Mod(r)) protein IncA PF04156.9 KKK17583.1 - 5.5e-05 22.8 19.1 0.018 14.6 10.1 2.1 2 0 0 2 2 2 2 IncA protein KLRAQ PF10205.4 KKK17583.1 - 0.00048 20.1 11.3 0.00048 20.1 7.8 2.3 2 1 1 3 3 3 1 Predicted coiled-coil domain-containing protein DUF972 PF06156.8 KKK17583.1 - 0.0028 17.9 13.4 0.012 15.9 5.6 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF972) Ax_dynein_light PF10211.4 KKK17583.1 - 0.0039 17.0 16.5 0.12 12.1 0.0 2.3 2 0 0 2 2 2 1 Axonemal dynein light chain APG6 PF04111.7 KKK17583.1 - 0.0054 15.8 19.6 0.24 10.3 0.3 2.0 2 0 0 2 2 2 2 Autophagy protein Apg6 Syntaxin-6_N PF09177.6 KKK17583.1 - 0.015 15.7 14.1 0.21 11.9 0.2 2.2 2 0 0 2 2 2 0 Syntaxin 6, N-terminal TMF_DNA_bd PF12329.3 KKK17583.1 - 0.018 14.7 29.4 0.029 14.1 9.6 3.3 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding bZIP_1 PF00170.16 KKK17583.1 - 0.021 14.7 24.4 0.12 12.3 0.8 4.1 2 1 2 4 4 4 0 bZIP transcription factor KAR9 PF08580.5 KKK17583.1 - 0.026 12.8 0.3 0.026 12.8 0.2 2.0 2 0 0 2 2 2 0 Yeast cortical protein KAR9 DUF4482 PF14818.1 KKK17583.1 - 0.05 14.2 1.0 0.05 14.2 0.7 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4482) Striatin PF08232.7 KKK17583.1 - 0.054 13.8 18.9 0.41 10.9 7.2 2.2 2 0 0 2 2 2 0 Striatin family MAD PF05557.8 KKK17583.1 - 0.056 11.5 15.4 0.059 11.4 6.0 2.0 2 0 0 2 2 2 0 Mitotic checkpoint protein ADIP PF11559.3 KKK17583.1 - 0.057 13.3 20.4 1.1 9.1 10.7 2.6 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding GAS PF13851.1 KKK17583.1 - 0.064 12.4 19.7 0.11 11.6 7.6 2.1 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding TMF_TATA_bd PF12325.3 KKK17583.1 - 0.094 12.4 24.4 0.17 11.6 10.5 2.4 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF3450 PF11932.3 KKK17583.1 - 0.095 11.9 12.8 2.5 7.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Myosin_tail_1 PF01576.14 KKK17583.1 - 0.14 9.8 22.1 0.13 9.9 0.9 2.1 2 0 0 2 2 2 0 Myosin tail MbeD_MobD PF04899.7 KKK17583.1 - 0.14 12.0 7.3 0.35 10.7 0.3 2.8 2 1 1 3 3 2 0 MbeD/MobD like DUF2730 PF10805.3 KKK17583.1 - 0.22 11.2 10.2 1.7 8.4 2.2 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2730) AAA_13 PF13166.1 KKK17583.1 - 0.22 9.9 14.2 1.2 7.4 0.3 2.2 2 0 0 2 2 2 0 AAA domain BLOC1_2 PF10046.4 KKK17583.1 - 0.24 11.5 13.9 1.1 9.4 0.2 2.9 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Vps16_C PF04840.7 KKK17583.1 - 0.26 10.1 8.1 0.039 12.8 2.6 1.7 2 0 0 2 2 2 0 Vps16, C-terminal region Uds1 PF15456.1 KKK17583.1 - 0.3 11.0 16.9 1.9 8.4 6.9 2.2 2 0 0 2 2 2 0 Up-regulated During Septation Phage_GP20 PF06810.6 KKK17583.1 - 0.34 10.3 18.3 0.33 10.3 7.7 2.3 2 0 0 2 2 2 0 Phage minor structural protein GP20 DUF641 PF04859.7 KKK17583.1 - 0.36 10.5 15.2 0.05 13.3 3.0 2.8 2 1 1 3 3 3 0 Plant protein of unknown function (DUF641) Laminin_II PF06009.7 KKK17583.1 - 0.41 10.3 11.3 3 7.5 0.2 2.1 2 0 0 2 2 2 0 Laminin Domain II DUF342 PF03961.8 KKK17583.1 - 0.45 8.8 11.5 2.1 6.6 4.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF342) CCDC155 PF14662.1 KKK17583.1 - 0.45 10.0 20.2 1.8 8.1 0.3 2.3 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 WXG100 PF06013.7 KKK17583.1 - 0.48 10.4 9.8 2.6 8.0 0.1 3.2 2 1 1 3 3 3 0 Proteins of 100 residues with WXG Fmp27_WPPW PF10359.4 KKK17583.1 - 0.51 8.6 14.4 0.41 9.0 5.2 2.0 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain DUF3584 PF12128.3 KKK17583.1 - 0.56 7.4 16.0 0.13 9.5 5.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) DUF4618 PF15397.1 KKK17583.1 - 0.59 9.4 15.6 0.25 10.6 0.7 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4618) DUF2188 PF09954.4 KKK17583.1 - 0.63 10.0 2.7 1.6 8.6 0.3 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2188) ERM PF00769.14 KKK17583.1 - 0.69 9.3 25.8 0.74 9.2 1.3 3.0 2 1 1 3 3 3 0 Ezrin/radixin/moesin family YbaB_DNA_bd PF02575.11 KKK17583.1 - 0.73 9.7 12.9 11 6.0 0.1 3.3 2 1 0 2 2 2 0 YbaB/EbfC DNA-binding family DUF4200 PF13863.1 KKK17583.1 - 0.77 9.7 24.4 0.3 11.0 0.4 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4200) DivIC PF04977.10 KKK17583.1 - 0.8 9.2 23.9 0.12 11.8 3.3 3.8 2 1 2 4 4 4 0 Septum formation initiator CENP-F_leu_zip PF10473.4 KKK17583.1 - 0.81 9.5 23.6 0.56 10.0 0.3 2.4 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TBPIP PF07106.8 KKK17583.1 - 0.83 9.1 20.4 1.9 8.0 0.5 2.7 2 1 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) EzrA PF06160.7 KKK17583.1 - 0.86 7.7 17.1 0.54 8.3 0.6 2.0 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA DUF724 PF05266.9 KKK17583.1 - 0.94 9.0 18.5 1 8.9 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF724) ATG16 PF08614.6 KKK17583.1 - 1 9.1 21.7 6.5 6.5 0.5 2.7 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) FlaC_arch PF05377.6 KKK17583.1 - 1 9.2 12.0 3.5 7.5 0.3 3.6 2 1 2 4 4 4 0 Flagella accessory protein C (FlaC) Spc7 PF08317.6 KKK17583.1 - 1.2 7.6 17.9 1.9 7.0 0.4 2.3 2 1 0 2 2 2 0 Spc7 kinetochore protein Nup54 PF13874.1 KKK17583.1 - 1.4 8.6 17.2 11 5.7 0.3 2.6 2 1 0 2 2 2 0 Nucleoporin complex subunit 54 DUF2458 PF10454.4 KKK17583.1 - 1.5 8.6 11.2 1.8 8.4 3.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2458) bZIP_2 PF07716.10 KKK17583.1 - 1.5 8.6 25.0 0.8 9.5 0.5 4.6 3 2 2 5 5 4 0 Basic region leucine zipper SlyX PF04102.7 KKK17583.1 - 1.7 9.0 18.2 4 7.8 3.0 3.5 2 1 1 3 3 3 0 SlyX Sipho_Gp157 PF05565.6 KKK17583.1 - 1.9 8.0 12.6 1.9 8.0 3.2 2.5 2 1 1 3 3 3 0 Siphovirus Gp157 Nsp1_C PF05064.8 KKK17583.1 - 2.1 8.0 15.7 0.38 10.4 4.9 2.5 2 1 0 2 2 2 0 Nsp1-like C-terminal region BRE1 PF08647.6 KKK17583.1 - 2.2 8.3 21.5 2.7 8.0 0.8 2.1 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase TACC PF05010.9 KKK17583.1 - 2.3 7.9 16.5 0.56 9.9 0.5 2.3 2 0 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC) HAP1_N PF04849.8 KKK17583.1 - 2.4 6.9 22.3 5.6 5.8 0.5 2.7 2 1 0 2 2 2 0 HAP1 N-terminal conserved region Mnd1 PF03962.10 KKK17583.1 - 2.5 7.7 18.7 5.5 6.6 0.6 2.3 2 0 0 2 2 2 0 Mnd1 family HAUS-augmin3 PF14932.1 KKK17583.1 - 2.9 6.9 18.9 1.3 8.1 0.3 2.0 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 SPX PF03105.14 KKK17583.1 - 3.3 7.4 10.4 16 5.1 6.7 1.9 1 1 0 1 1 1 0 SPX domain Relaxase PF03432.9 KKK17583.1 - 3.4 6.9 9.0 2.1 7.7 0.1 2.1 2 0 0 2 2 2 0 Relaxase/Mobilisation nuclease domain Prefoldin PF02996.12 KKK17583.1 - 3.6 7.2 16.6 1.6 8.3 0.2 3.6 2 1 1 3 3 3 0 Prefoldin subunit Herpes_UL6 PF01763.11 KKK17583.1 - 3.7 5.6 9.8 0.96 7.5 2.9 2.0 2 0 0 2 2 2 0 Herpesvirus UL6 like DivIVA PF05103.8 KKK17583.1 - 4.3 7.4 20.0 8.7 6.4 0.3 3.2 2 1 0 2 2 2 0 DivIVA protein DUF4140 PF13600.1 KKK17583.1 - 4.6 7.7 18.9 4.8 7.6 0.1 3.2 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) Fib_alpha PF08702.5 KKK17583.1 - 4.8 7.2 10.5 9 6.4 2.6 2.7 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Seryl_tRNA_N PF02403.17 KKK17583.1 - 4.9 7.2 18.9 4.5 7.3 0.1 2.8 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain FlxA PF14282.1 KKK17583.1 - 5 7.1 16.6 18 5.3 0.0 2.5 2 1 0 2 2 2 0 FlxA-like protein DUF4201 PF13870.1 KKK17583.1 - 5.9 6.2 19.8 2.2 7.6 0.6 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4201) XhlA PF10779.4 KKK17583.1 - 7.1 6.6 18.3 14 5.6 2.0 3.3 3 0 0 3 3 3 0 Haemolysin XhlA CDC37_N PF03234.9 KKK17583.1 - 7.5 6.8 15.6 4.1e+02 1.1 10.8 2.5 1 1 0 1 1 1 0 Cdc37 N terminal kinase binding PAP_assoc PF03828.14 KKK17584.1 - 7.2e-16 57.8 0.3 1.5e-15 56.8 0.2 1.6 1 0 0 1 1 1 1 Cid1 family poly A polymerase GFA PF04828.9 KKK17584.1 - 1.7e-13 50.3 4.9 1.8e-10 40.6 0.4 2.6 2 0 0 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme NTP_transf_2 PF01909.18 KKK17584.1 - 1.6e-08 34.7 0.0 3.8e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain Pam16 PF03656.8 KKK17585.1 - 3.1e-35 120.7 0.5 3.9e-35 120.4 0.3 1.0 1 0 0 1 1 1 1 Pam16 Pex24p PF06398.6 KKK17586.1 - 9.7e-99 330.5 1.0 1.4e-98 330.0 0.7 1.2 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Fungal_trans_2 PF11951.3 KKK17587.1 - 3.4e-48 164.1 0.4 6.3e-48 163.2 0.1 1.5 1 1 1 2 2 2 1 Fungal specific transcription factor domain PHA-1 PF06542.6 KKK17587.1 - 0.18 10.5 0.3 0.34 9.5 0.2 1.4 1 0 0 1 1 1 0 Regulator protein PHA-1 Nop25 PF09805.4 KKK17588.1 - 1.1e-34 119.4 21.3 1.1e-34 119.4 14.7 3.1 2 1 1 3 3 3 1 Nucleolar protein 12 (25kDa) DUF4522 PF15022.1 KKK17588.1 - 0.0085 15.7 2.6 0.0085 15.7 1.8 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF4522) CAF-1_p150 PF11600.3 KKK17588.1 - 9.7 5.5 58.0 2.6 7.3 17.2 2.1 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal ATP-synt_S1 PF05827.7 KKK17589.1 - 1.8e-67 227.6 0.4 2.1e-67 227.3 0.3 1.0 1 0 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) Nuc_recep-AF1 PF11825.3 KKK17589.1 - 0.078 12.8 0.1 0.15 12.0 0.1 1.5 1 0 0 1 1 1 0 Nuclear/hormone receptor activator site AF-1 MFS_1 PF07690.11 KKK17591.1 - 3.9e-31 108.0 44.9 3.9e-31 108.0 31.1 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KKK17591.1 - 5.7e-10 38.3 42.3 8.3e-09 34.5 9.8 2.7 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_2 PF13347.1 KKK17591.1 - 2.6e-07 29.3 9.5 2.6e-07 29.3 6.6 2.6 1 1 2 3 3 3 1 MFS/sugar transport protein MFS_1 PF07690.11 KKK17592.1 - 7e-22 77.6 9.8 1e-21 77.0 6.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KKK17592.1 - 1e-17 63.8 3.3 1.4e-17 63.4 2.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter Innate_immun PF12782.2 KKK17592.1 - 1.2 8.3 6.7 1.9 7.6 4.7 1.2 1 0 0 1 1 1 0 Invertebrate innate immunity transcript family Abhydrolase_5 PF12695.2 KKK17598.1 - 1.1e-23 83.6 0.0 1.6e-23 83.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KKK17598.1 - 1e-19 71.3 0.0 1.4e-18 67.5 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 KKK17598.1 - 5.8e-08 31.5 0.2 0.011 14.2 0.1 3.0 2 1 1 3 3 3 2 Acetyl xylan esterase (AXE1) Abhydrolase_1 PF00561.15 KKK17598.1 - 4.3e-07 29.7 0.0 5.5e-05 22.8 0.0 2.3 2 1 0 3 3 3 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KKK17598.1 - 7e-06 25.4 0.0 0.00011 21.5 0.0 2.3 2 1 0 2 2 2 1 Prolyl oligopeptidase family FSH1 PF03959.8 KKK17598.1 - 4.2e-05 23.0 0.0 0.00014 21.3 0.0 1.8 2 0 0 2 2 2 1 Serine hydrolase (FSH1) Abhydrolase_3 PF07859.8 KKK17598.1 - 4.4e-05 23.1 0.0 6.8e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 KKK17598.1 - 0.0001 21.8 0.0 0.16 11.4 0.0 2.4 1 1 1 2 2 2 2 Phospholipase/Carboxylesterase BAAT_C PF08840.6 KKK17598.1 - 0.00013 21.7 0.0 0.011 15.4 0.0 2.3 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.13 KKK17598.1 - 0.00063 19.0 0.0 0.094 11.9 0.0 2.4 3 0 0 3 3 3 1 Dienelactone hydrolase family PGAP1 PF07819.8 KKK17598.1 - 0.0045 16.5 0.0 0.027 14.0 0.0 2.0 1 1 0 1 1 1 1 PGAP1-like protein Hydrolase_4 PF12146.3 KKK17598.1 - 0.0066 16.2 0.1 0.013 15.3 0.1 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Esterase PF00756.15 KKK17598.1 - 0.0077 15.6 0.0 0.015 14.6 0.0 1.4 1 0 0 1 1 1 1 Putative esterase DUF818 PF05677.7 KKK17598.1 - 0.02 13.6 0.0 0.03 13.0 0.0 1.1 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) DUF2305 PF10230.4 KKK17598.1 - 0.02 14.2 0.0 0.15 11.4 0.0 1.9 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2305) Lipase_3 PF01764.20 KKK17598.1 - 0.031 13.8 0.0 0.05 13.2 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) DUF2974 PF11187.3 KKK17598.1 - 0.19 11.0 0.0 0.31 10.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Proteasome PF00227.21 KKK17599.1 - 7.3e-49 165.6 0.3 8.4e-49 165.4 0.2 1.0 1 0 0 1 1 1 1 Proteasome subunit Cyclin PF08613.6 KKK17600.1 - 8.3e-38 130.1 6.3 2.5e-22 79.9 0.0 3.2 3 0 0 3 3 3 2 Cyclin RabGAP-TBC PF00566.13 KKK17602.1 - 3.6e-26 91.9 0.0 5.4e-26 91.4 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Synaphin PF05835.7 KKK17602.1 - 0.09 12.9 3.3 0.23 11.6 2.3 1.6 1 0 0 1 1 1 0 Synaphin protein Telomerase_RBD PF12009.3 KKK17603.1 - 2.4e-43 147.2 0.1 4.8e-43 146.3 0.1 1.5 1 0 0 1 1 1 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.22 KKK17603.1 - 3.2e-13 49.5 0.0 1.4e-12 47.4 0.0 1.9 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RhoGAP PF00620.22 KKK17604.1 - 5.3e-30 104.0 0.0 9e-30 103.2 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain Myc_N PF01056.13 KKK17605.1 - 0.0034 16.5 0.1 0.0063 15.7 0.0 1.4 1 0 0 1 1 1 1 Myc amino-terminal region MutS_V PF00488.16 KKK17606.1 - 2.5e-88 295.4 0.0 4.6e-88 294.5 0.0 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 KKK17606.1 - 8e-35 120.4 0.6 1.7e-34 119.3 0.4 1.6 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 KKK17606.1 - 1.3e-28 99.3 0.0 3.5e-28 97.8 0.0 1.8 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.12 KKK17606.1 - 5.3e-10 39.4 0.0 1.7e-09 37.8 0.0 2.0 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.13 KKK17606.1 - 7.5e-07 29.2 0.1 2.1e-06 27.8 0.0 1.8 1 0 0 1 1 1 1 MutS family domain IV Mito_fiss_reg PF05308.6 KKK17607.1 - 0.01 15.2 4.5 0.022 14.1 3.1 1.5 1 0 0 1 1 1 0 Mitochondrial fission regulator DUF1470 PF07336.6 KKK17607.1 - 0.37 11.1 4.6 0.17 12.2 0.6 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1470) CAP_N PF01213.14 KKK17607.1 - 1.3 8.2 11.2 0.63 9.2 5.5 1.9 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal DAP3 PF10236.4 KKK17609.1 - 8.4e-109 363.2 0.0 1e-108 362.9 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 T2SE PF00437.15 KKK17609.1 - 0.00094 18.1 0.0 0.0016 17.4 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_14 PF13173.1 KKK17609.1 - 0.024 14.5 0.0 0.042 13.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 KKK17609.1 - 0.028 14.3 0.0 0.058 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain RRS1 PF04939.7 KKK17610.1 - 9.9e-60 200.7 1.8 1.2e-59 200.5 1.3 1.0 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) Sel1 PF08238.7 KKK17611.1 - 4.3e-11 43.0 7.8 1.4e-07 31.9 0.0 4.1 4 0 0 4 4 4 2 Sel1 repeat TBPIP PF07106.8 KKK17612.1 - 4.9e-15 55.4 1.7 6.4e-15 55.1 1.2 1.1 1 0 0 1 1 1 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DivIC PF04977.10 KKK17612.1 - 0.002 17.5 5.2 0.0042 16.5 0.6 2.4 2 0 0 2 2 2 1 Septum formation initiator Vps51 PF08700.6 KKK17612.1 - 0.0021 17.8 0.5 0.71 9.7 0.1 2.3 2 0 0 2 2 2 1 Vps51/Vps67 EzrA PF06160.7 KKK17612.1 - 0.0026 16.0 0.9 0.0031 15.7 0.6 1.2 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA Laminin_I PF06008.9 KKK17612.1 - 0.0099 15.2 3.8 0.013 14.8 2.6 1.2 1 0 0 1 1 1 1 Laminin Domain I DUF4140 PF13600.1 KKK17612.1 - 0.011 16.1 7.1 0.027 14.8 1.2 2.4 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Seryl_tRNA_N PF02403.17 KKK17612.1 - 0.017 15.1 3.5 0.027 14.4 2.5 1.5 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain ERM PF00769.14 KKK17612.1 - 0.018 14.5 3.5 0.024 14.2 2.4 1.3 1 0 0 1 1 1 0 Ezrin/radixin/moesin family TraF_2 PF13729.1 KKK17612.1 - 0.037 12.8 0.1 0.044 12.5 0.1 1.1 1 0 0 1 1 1 0 F plasmid transfer operon, TraF, protein Mnd1 PF03962.10 KKK17612.1 - 0.079 12.6 4.6 0.12 12.0 3.2 1.2 1 0 0 1 1 1 0 Mnd1 family PhoU PF01895.14 KKK17612.1 - 0.085 13.3 0.2 0.16 12.4 0.1 1.5 1 0 0 1 1 1 0 PhoU domain DUF2730 PF10805.3 KKK17612.1 - 0.18 11.5 1.5 0.41 10.4 0.9 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) IncA PF04156.9 KKK17612.1 - 0.24 10.9 12.1 0.34 10.4 8.4 1.3 1 1 0 1 1 1 0 IncA protein DUF4337 PF14235.1 KKK17612.1 - 1.2 8.9 5.5 7 6.4 2.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) CheY-binding PF09078.6 KKK17612.1 - 1.4 8.9 4.2 15 5.6 0.4 2.4 2 0 0 2 2 2 0 CheY binding FlxA PF14282.1 KKK17612.1 - 1.5 8.8 7.1 6.7 6.7 4.9 2.0 1 1 0 1 1 1 0 FlxA-like protein DivIVA PF05103.8 KKK17612.1 - 2.3 8.2 9.2 5.2 7.1 1.6 2.3 1 1 0 2 2 2 0 DivIVA protein Lge1 PF11488.3 KKK17612.1 - 3.6 7.8 7.7 5.9 7.1 0.8 2.3 1 1 1 2 2 2 0 Transcriptional regulatory protein LGE1 APG6 PF04111.7 KKK17612.1 - 5.5 5.9 8.5 15 4.4 5.9 1.7 1 1 0 1 1 1 0 Autophagy protein Apg6 Prenyltrans PF00432.16 KKK17613.1 - 1.2e-52 175.1 10.6 1.1e-11 44.0 0.0 6.2 6 0 0 6 6 6 6 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 KKK17613.1 - 1.5e-28 99.4 0.0 9.2e-12 45.3 0.0 3.9 1 1 3 4 4 4 4 Prenyltransferase-like Prenyltrans_1 PF13243.1 KKK17613.1 - 1.9e-08 34.2 0.0 0.00099 19.0 0.0 3.4 2 2 1 3 3 3 2 Prenyltransferase-like RhoGEF PF00621.15 KKK17614.1 - 2e-36 125.5 0.0 4.1e-36 124.5 0.0 1.6 1 0 0 1 1 1 1 RhoGEF domain BAR PF03114.13 KKK17614.1 - 1.2e-15 57.6 1.8 2.7e-15 56.5 1.2 1.5 1 0 0 1 1 1 1 BAR domain Peptidase_C48 PF02902.14 KKK17614.1 - 2.7e-05 23.9 0.1 0.00034 20.2 0.0 2.3 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Abhydrolase_6 PF12697.2 KKK17615.1 - 3.4e-05 23.8 0.1 3.4e-05 23.8 0.0 3.0 3 1 0 3 3 3 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KKK17615.1 - 0.0081 15.7 0.0 0.018 14.6 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF676 PF05057.9 KKK17615.1 - 0.064 12.5 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) LCAT PF02450.10 KKK17615.1 - 0.14 11.1 0.0 0.22 10.4 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase GLE1 PF07817.8 KKK17628.1 - 5.4e-09 35.3 4.0 1.9e-05 23.7 0.1 4.1 2 2 1 3 3 3 3 GLE1-like protein MMgT PF10270.4 KKK17629.1 - 9.6e-36 122.4 0.0 1.1e-35 122.2 0.0 1.0 1 0 0 1 1 1 1 Membrane magnesium transporter EF1_GNE PF00736.14 KKK17630.1 - 1.3e-30 104.9 4.1 2.1e-30 104.2 2.8 1.3 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.4 KKK17630.1 - 3.7e-12 46.1 4.5 3.7e-12 46.1 3.2 2.6 3 0 0 3 3 3 1 Eukaryotic elongation factor 1 beta central acidic region GST_C PF00043.20 KKK17630.1 - 0.00053 19.9 0.2 0.0016 18.3 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KKK17630.1 - 0.00071 20.0 0.0 0.0017 18.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KKK17630.1 - 0.0025 17.6 0.3 0.18 11.7 0.2 2.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain YL1 PF05764.8 KKK17630.1 - 0.12 11.9 6.1 0.027 14.0 0.8 1.9 2 0 0 2 2 2 0 YL1 nuclear protein DNA_pol3_a_NII PF11490.3 KKK17630.1 - 2.9 7.5 9.0 0.25 10.9 0.8 2.3 2 1 0 2 2 2 0 DNA polymerase III polC-type N-terminus II AAA_2 PF07724.9 KKK17631.1 - 3.1e-46 157.4 0.0 4.3e-44 150.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.4 KKK17631.1 - 3.5e-26 90.9 0.2 1.2e-25 89.2 0.1 2.0 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.24 KKK17631.1 - 1.6e-19 70.3 0.0 1.7e-10 41.2 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KKK17631.1 - 2.2e-13 50.1 1.1 1.6e-08 34.3 0.0 3.3 4 1 0 4 4 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KKK17631.1 - 4e-11 43.2 10.8 0.0001 22.3 0.0 5.5 4 2 1 6 6 6 2 AAA ATPase domain AAA_22 PF13401.1 KKK17631.1 - 5.8e-10 39.4 0.7 0.0033 17.5 0.0 3.4 2 1 1 4 4 3 2 AAA domain Sigma54_activat PF00158.21 KKK17631.1 - 2.1e-08 33.8 0.3 7.9e-05 22.1 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_14 PF13173.1 KKK17631.1 - 2e-06 27.7 0.0 0.065 13.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain Arch_ATPase PF01637.13 KKK17631.1 - 2.4e-06 27.4 5.0 0.049 13.3 0.0 4.6 3 2 0 3 3 3 1 Archaeal ATPase NACHT PF05729.7 KKK17631.1 - 8.6e-06 25.4 0.1 0.077 12.6 0.0 2.6 2 0 0 2 2 2 2 NACHT domain AAA_18 PF13238.1 KKK17631.1 - 1.8e-05 25.0 3.1 0.089 13.1 0.0 3.3 3 0 0 3 3 3 2 AAA domain MobB PF03205.9 KKK17631.1 - 4.5e-05 23.1 0.0 0.022 14.4 0.0 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.1 KKK17631.1 - 6.3e-05 23.7 7.5 0.039 14.7 0.1 4.0 3 2 0 3 3 3 2 AAA domain AAA_28 PF13521.1 KKK17631.1 - 6.5e-05 22.9 3.7 0.056 13.3 0.0 4.3 4 1 0 4 4 4 1 AAA domain TrwB_AAD_bind PF10412.4 KKK17631.1 - 0.00015 20.5 0.1 0.063 11.8 0.0 2.6 3 0 0 3 3 3 1 Type IV secretion-system coupling protein DNA-binding domain AAA_19 PF13245.1 KKK17631.1 - 0.00019 21.1 0.0 0.011 15.5 0.0 2.6 2 0 0 2 2 2 1 Part of AAA domain IstB_IS21 PF01695.12 KKK17631.1 - 0.00026 20.4 0.0 0.78 9.1 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein SRP54 PF00448.17 KKK17631.1 - 0.00027 20.4 0.0 0.044 13.2 0.0 2.5 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain RNA_helicase PF00910.17 KKK17631.1 - 0.00079 19.5 0.0 0.61 10.2 0.0 2.8 2 1 0 2 2 2 1 RNA helicase ABC_tran PF00005.22 KKK17631.1 - 0.0026 18.0 1.1 1.7 8.9 0.0 3.3 3 0 0 3 3 3 1 ABC transporter Mg_chelatase PF01078.16 KKK17631.1 - 0.0027 16.9 0.1 2 7.5 0.0 3.1 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI ResIII PF04851.10 KKK17631.1 - 0.0054 16.5 4.1 2 8.1 0.0 3.5 3 1 0 3 3 3 2 Type III restriction enzyme, res subunit DUF853 PF05872.7 KKK17631.1 - 0.0067 14.8 0.2 0.056 11.7 0.0 2.3 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF853) AAA_33 PF13671.1 KKK17631.1 - 0.0075 16.1 0.0 3.9 7.3 0.0 2.8 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.12 KKK17631.1 - 0.008 15.7 0.1 0.16 11.4 0.0 2.3 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_25 PF13481.1 KKK17631.1 - 0.0081 15.5 0.9 1.9 7.8 0.1 3.2 2 2 1 3 3 3 1 AAA domain AAA_10 PF12846.2 KKK17631.1 - 0.0098 15.3 0.1 0.16 11.3 0.0 2.8 2 2 0 2 2 2 1 AAA-like domain DUF815 PF05673.8 KKK17631.1 - 0.01 14.8 0.1 0.38 9.6 0.1 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF815) PduV-EutP PF10662.4 KKK17631.1 - 0.01 15.3 0.0 0.64 9.5 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_30 PF13604.1 KKK17631.1 - 0.01 15.4 6.0 0.17 11.4 0.0 4.2 4 1 0 5 5 4 0 AAA domain AAA_24 PF13479.1 KKK17631.1 - 0.013 15.0 0.0 0.7 9.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF3333 PF11812.3 KKK17631.1 - 0.015 15.3 1.8 0.021 14.8 0.0 2.2 2 0 0 2 2 1 0 Domain of unknown function (DUF3333) DUF258 PF03193.11 KKK17631.1 - 0.02 14.1 0.0 4 6.5 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Zeta_toxin PF06414.7 KKK17631.1 - 0.023 13.8 3.0 0.19 10.8 0.0 2.9 3 0 0 3 3 2 0 Zeta toxin UPF0079 PF02367.12 KKK17631.1 - 0.024 14.2 0.0 6.9 6.3 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_23 PF13476.1 KKK17631.1 - 0.043 14.1 8.2 1.4 9.1 2.9 3.8 4 0 0 4 4 4 0 AAA domain Miro PF08477.8 KKK17631.1 - 0.076 13.5 1.5 1.9 8.9 0.0 2.8 3 0 0 3 3 2 0 Miro-like protein UvrD-helicase PF00580.16 KKK17631.1 - 0.097 11.9 5.2 0.26 10.5 0.1 2.2 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain IncA PF04156.9 KKK17631.1 - 0.23 11.0 13.6 0.44 10.1 9.0 1.8 2 0 0 2 2 1 0 IncA protein GrpE PF01025.14 KKK17631.1 - 0.23 11.0 9.4 0.59 9.6 6.5 1.7 1 0 0 1 1 1 0 GrpE Prefoldin_2 PF01920.15 KKK17631.1 - 0.5 10.1 13.4 1.6 8.5 2.5 3.0 1 1 1 2 2 2 0 Prefoldin subunit V_ATPase_I PF01496.14 KKK17631.1 - 0.6 7.8 6.1 0.85 7.4 4.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Atg14 PF10186.4 KKK17631.1 - 1.2 7.9 9.5 2.4 7.0 6.6 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF2968 PF11180.3 KKK17631.1 - 1.4 8.2 10.0 3.4 7.0 6.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) DivIC PF04977.10 KKK17631.1 - 1.5 8.3 14.2 2.1 7.8 6.9 2.6 1 1 1 2 2 2 0 Septum formation initiator APG6 PF04111.7 KKK17631.1 - 2.8 6.9 10.0 4.7 6.1 6.9 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 MutS_V PF00488.16 KKK17632.1 - 4.5e-27 94.9 0.1 1.2e-26 93.5 0.1 1.7 2 0 0 2 2 2 1 MutS domain V MutS_III PF05192.13 KKK17632.1 - 2.8e-20 72.9 0.1 9.8e-20 71.2 0.0 2.0 2 0 0 2 2 2 1 MutS domain III MutS_IV PF05190.13 KKK17632.1 - 0.0035 17.4 0.0 0.01 15.9 0.0 1.8 1 0 0 1 1 1 1 MutS family domain IV Sas10 PF09368.5 KKK17633.1 - 7e-30 103.0 7.4 7e-30 103.0 5.1 3.2 3 0 0 3 3 3 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.10 KKK17633.1 - 2e-13 50.3 1.2 7.6e-13 48.4 0.0 2.7 3 0 0 3 3 3 1 Sas10/Utp3/C1D family adh_short PF00106.20 KKK17634.1 - 3e-19 69.5 0.0 4.1e-19 69.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KKK17634.1 - 2.4e-08 33.8 0.0 3.3e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KKK17634.1 - 2.2e-07 30.8 0.0 4.1e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KKK17634.1 - 0.00092 18.7 0.0 0.0017 17.8 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KKK17634.1 - 0.0021 18.1 0.1 0.0049 16.8 0.1 1.7 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_7 PF13241.1 KKK17634.1 - 0.0044 17.2 0.4 0.0096 16.1 0.2 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding THF_DHG_CYH_C PF02882.14 KKK17634.1 - 0.0047 16.0 0.2 0.0085 15.1 0.1 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Shikimate_DH PF01488.15 KKK17634.1 - 0.0047 17.0 0.1 0.011 15.8 0.1 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Polysacc_synt_2 PF02719.10 KKK17634.1 - 0.045 12.6 0.0 0.072 11.9 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein 3HCDH_N PF02737.13 KKK17634.1 - 0.064 12.8 0.3 0.12 11.9 0.2 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FA_hydroxylase PF04116.8 KKK17635.1 - 1.8e-13 50.9 11.0 1.8e-13 50.9 7.7 2.4 3 1 0 3 3 3 1 Fatty acid hydroxylase superfamily Spt5_N PF11942.3 KKK17635.1 - 3.2 8.4 8.7 5.8 7.6 6.0 1.3 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal DUF904 PF06005.7 KKK17635.1 - 6.2 7.1 6.2 2.5 8.4 0.6 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF904) Ribosomal_L6e PF01159.14 KKK17636.1 - 4.4e-37 126.6 0.3 7.9e-37 125.8 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L6e DUF1070 PF06376.7 KKK17636.1 - 0.14 12.0 0.6 0.32 10.9 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1070) Proteasom_Rpn13 PF04683.8 KKK17637.1 - 1.3e-27 95.6 0.0 2e-27 95.1 0.0 1.3 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor Ion_trans PF00520.26 KKK17638.1 - 4.6e-99 329.6 86.4 6.7e-35 120.1 4.3 5.5 6 0 0 6 6 6 4 Ion transport protein EF-hand_1 PF00036.27 KKK17638.1 - 0.0016 17.6 0.0 0.0045 16.2 0.0 1.9 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 KKK17638.1 - 0.011 15.4 0.0 0.055 13.3 0.0 2.2 2 0 0 2 2 2 0 EF-hand domain EF-hand_7 PF13499.1 KKK17638.1 - 0.058 13.5 0.0 0.19 11.9 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain pair UQ_con PF00179.21 KKK17639.1 - 2.7e-35 120.8 0.0 4.3e-35 120.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KKK17639.1 - 0.0023 17.6 0.0 0.0046 16.7 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic E2 family B RNB PF00773.14 KKK17640.1 - 5.7e-81 272.3 0.1 5.3e-80 269.1 0.0 2.2 2 0 0 2 2 2 1 RNB domain Pkinase PF00069.20 KKK17643.1 - 0.0052 15.9 0.0 0.0075 15.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase PF00069.20 KKK17644.1 - 1.1e-71 241.0 0.0 1.5e-71 240.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK17644.1 - 1.9e-48 164.8 0.0 2.7e-48 164.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KKK17644.1 - 2.6e-05 23.3 0.0 8.3e-05 21.6 0.0 1.7 2 0 0 2 2 2 1 Kinase-like F-box-like PF12937.2 KKK17645.1 - 1.6e-08 34.1 0.1 4.5e-08 32.7 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KKK17645.1 - 0.12 12.0 0.6 3.3 7.4 0.1 2.7 2 0 0 2 2 2 0 F-box domain DUF4048 PF13257.1 KKK17646.1 - 3.4e-83 279.1 16.5 3.4e-83 279.1 11.5 3.1 4 0 0 4 4 4 1 Domain of unknown function (DUF4048) End3 PF12761.2 KKK17646.1 - 0.024 14.2 3.0 0.046 13.3 2.1 1.4 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 IncA PF04156.9 KKK17646.1 - 0.031 13.8 0.2 0.053 13.1 0.1 1.4 1 0 0 1 1 1 0 IncA protein GrpE PF01025.14 KKK17646.1 - 0.052 13.0 0.4 0.092 12.2 0.3 1.3 1 0 0 1 1 1 0 GrpE DIOX_N PF14226.1 KKK17647.1 - 3.5e-15 56.5 0.0 6.6e-15 55.6 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KKK17647.1 - 5.9e-15 55.3 0.2 1.4e-14 54.1 0.0 1.7 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily AMP-binding PF00501.23 KKK17648.1 - 2.2e-62 210.7 0.0 2.9e-62 210.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.20 KKK17648.1 - 6.5e-08 32.7 0.0 1.3e-07 31.7 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.1 KKK17648.1 - 8.9e-05 23.3 0.0 0.00024 22.0 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF3283 PF11686.3 KKK17648.1 - 0.11 12.2 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3283) PS_Dcarbxylase PF02666.10 KKK17649.1 - 6.1e-35 120.3 0.0 8.4e-35 119.8 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase PSDC PF12588.3 KKK17649.1 - 4.3e-31 107.4 0.0 7.7e-31 106.5 0.0 1.4 1 0 0 1 1 1 1 Phophatidylserine decarboxylase RnfC_N PF13375.1 KKK17649.1 - 0.0013 18.4 0.0 0.98 9.1 0.0 2.9 3 0 0 3 3 3 2 RnfC Barrel sandwich hybrid domain Cnd3 PF12719.2 KKK17650.1 - 2.8e-94 315.4 0.7 3e-93 312.0 0.1 2.6 2 1 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.1 KKK17650.1 - 9.9e-11 41.7 2.2 7.8e-07 29.2 0.1 4.4 2 1 2 4 4 4 3 HEAT repeats HEAT_EZ PF13513.1 KKK17650.1 - 1.3e-07 31.8 2.7 0.0033 17.8 0.1 4.7 4 0 0 4 4 4 2 HEAT-like repeat HEAT PF02985.17 KKK17650.1 - 9.4e-05 22.1 4.9 0.035 14.1 0.0 5.9 6 0 0 6 6 6 1 HEAT repeat Adaptin_N PF01602.15 KKK17650.1 - 0.0026 16.1 0.4 0.19 9.9 0.1 2.5 2 0 0 2 2 2 2 Adaptin N terminal region PyrBI_leader PF08052.6 KKK17650.1 - 0.11 12.2 0.2 0.25 11.1 0.2 1.5 1 0 0 1 1 1 0 PyrBI operon leader peptide Cohesin_HEAT PF12765.2 KKK17650.1 - 0.13 12.2 1.5 0.89 9.5 0.1 3.0 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion PALP PF00291.20 KKK17651.1 - 2.8e-60 204.1 0.1 3.4e-60 203.8 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Oxidored_molyb PF00174.14 KKK17652.1 - 8.4e-47 158.7 0.0 1.1e-46 158.2 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.11 KKK17652.1 - 3.4e-20 72.0 0.9 7.6e-20 70.8 0.6 1.6 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain zf-CHY PF05495.7 KKK17653.1 - 2.6e-14 53.1 20.7 3.3e-14 52.8 14.3 1.1 1 0 0 1 1 1 1 CHY zinc finger zf-RING_3 PF14369.1 KKK17653.1 - 0.025 14.5 1.0 0.025 14.5 0.7 2.6 1 1 1 2 2 2 0 zinc-finger Zn-ribbon_8 PF09723.5 KKK17653.1 - 0.13 12.1 12.8 1.3 9.0 5.4 2.5 2 0 0 2 2 2 0 Zinc ribbon domain Tmemb_55A PF09788.4 KKK17653.1 - 0.17 10.9 8.7 0.2 10.7 6.1 1.1 1 0 0 1 1 1 0 Transmembrane protein 55A Zn_Tnp_IS1595 PF12760.2 KKK17653.1 - 0.21 11.4 12.3 2.1 8.1 5.7 2.6 2 1 0 2 2 2 0 Transposase zinc-ribbon domain C1_4 PF07975.7 KKK17653.1 - 0.21 11.6 14.8 1.3 9.1 4.5 2.5 1 1 2 3 3 3 0 TFIIH C1-like domain Cytochrome_C7 PF14522.1 KKK17653.1 - 1.3 8.6 14.8 1.9 8.1 10.2 1.3 1 0 0 1 1 1 0 Cytochrome c7 zf-TFIIB PF13453.1 KKK17653.1 - 1.7 7.9 8.8 7.6 5.8 0.0 2.5 2 0 0 2 2 2 0 Transcription factor zinc-finger DUF3797 PF12677.2 KKK17653.1 - 2.5 7.7 0.0 2.5 7.7 0.0 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF3797) HypA PF01155.14 KKK17653.1 - 5.7 6.6 12.0 0.23 11.1 2.7 2.1 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family Ribosomal_L37ae PF01780.14 KKK17653.1 - 8.7 6.2 7.0 7.2 6.5 3.0 1.9 1 1 1 2 2 2 0 Ribosomal L37ae protein family Proteasome PF00227.21 KKK17654.1 - 7.8e-56 188.3 0.0 1.1e-55 187.9 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 KKK17654.1 - 6.4e-14 50.9 0.1 6.4e-14 50.9 0.0 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Terminase_5 PF06056.7 KKK17654.1 - 0.073 12.6 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) zf-RanBP PF00641.13 KKK17655.1 - 9.1e-21 72.6 9.1 6e-11 41.2 1.1 2.4 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others RRM_1 PF00076.17 KKK17655.1 - 2.2e-08 33.6 0.0 5.6e-08 32.3 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KKK17655.1 - 1.4e-06 28.1 0.0 7.5e-06 25.8 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RNase_T PF00929.19 KKK17655.1 - 1.5e-06 28.6 0.0 2.5e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Exonuclease DZR PF12773.2 KKK17655.1 - 0.49 10.2 8.3 0.77 9.6 0.8 2.5 2 0 0 2 2 2 0 Double zinc ribbon MFS_1 PF07690.11 KKK17656.1 - 3.1e-54 184.0 27.8 1.8e-48 165.1 14.1 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Pkinase PF00069.20 KKK17656.1 - 1.5e-16 60.3 0.0 2.5e-16 59.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK17656.1 - 2e-06 27.0 0.1 1.7e-05 24.0 0.1 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase MFS_3 PF05977.8 KKK17656.1 - 0.00082 17.6 2.9 0.00082 17.6 2.0 2.3 2 0 0 2 2 2 2 Transmembrane secretion effector Mem_trans PF03547.13 KKK17656.1 - 0.17 10.1 2.2 0.25 9.6 0.0 2.1 2 1 0 2 2 2 0 Membrane transport protein Tim17 PF02466.14 KKK17657.1 - 6.1e-53 178.2 6.9 6.1e-53 178.2 4.8 1.9 2 0 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family Exo_endo_phos PF03372.18 KKK17658.1 - 1.8e-22 80.5 1.0 2.2e-22 80.2 0.0 1.7 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family PQQ_2 PF13360.1 KKK17658.1 - 0.016 14.6 0.0 0.055 12.9 0.0 1.8 1 1 0 1 1 1 0 PQQ-like domain WD40 PF00400.27 KKK17658.1 - 4.9 7.2 9.5 2.4 8.1 1.8 3.3 3 0 0 3 3 3 0 WD domain, G-beta repeat BTB PF00651.26 KKK17659.1 - 7.6e-07 29.0 1.7 1.6e-06 28.0 0.4 1.9 2 0 0 2 2 2 1 BTB/POZ domain Mito_carr PF00153.22 KKK17674.1 - 4.3e-05 23.1 0.1 5.8e-05 22.7 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial carrier protein FYVE PF01363.16 KKK17675.1 - 1.5e-15 56.8 7.4 2.2e-15 56.2 5.1 1.2 1 0 0 1 1 1 1 FYVE zinc finger IBR PF01485.16 KKK17675.1 - 0.014 15.2 1.2 0.033 14.0 0.8 1.5 1 0 0 1 1 1 0 IBR domain zf-AN1 PF01428.11 KKK17675.1 - 0.028 14.2 9.4 0.057 13.3 6.5 1.5 1 0 0 1 1 1 0 AN1-like Zinc finger UPF0547 PF10571.4 KKK17675.1 - 8.7 6.1 8.2 25 4.6 5.7 1.8 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 Ribosomal_S27 PF01599.14 KKK17704.1 - 1.8e-15 56.5 0.1 2.9e-15 55.8 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S27a Pkinase PF00069.20 KKK17711.1 - 5.3e-47 160.1 0.0 8e-47 159.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK17711.1 - 2.6e-17 62.7 0.0 3.9e-17 62.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KKK17711.1 - 0.0004 19.4 0.0 0.00066 18.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 KKK17711.1 - 0.0012 18.2 0.2 0.0022 17.3 0.1 1.4 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 KKK17711.1 - 0.026 13.6 0.0 0.045 12.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PsaA_PsaB PF00223.14 KKK17711.1 - 0.062 11.3 0.0 0.094 10.7 0.0 1.1 1 0 0 1 1 1 0 Photosystem I psaA/psaB protein APH PF01636.18 KKK17711.1 - 0.096 12.3 0.1 0.33 10.6 0.1 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family Ribosomal_S8e PF01201.17 KKK17712.1 - 1.3e-35 122.4 5.1 4.5e-35 120.6 3.5 1.8 1 1 0 1 1 1 1 Ribosomal protein S8e DUF2390 PF09523.5 KKK17712.1 - 1.8 8.7 7.9 3.6 7.7 5.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2390) Fungal_trans PF04082.13 KKK17713.1 - 2.8e-22 78.8 0.1 5.2e-22 77.9 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain RIB43A PF05914.7 KKK17714.1 - 0.00078 18.1 0.3 0.0011 17.6 0.2 1.1 1 0 0 1 1 1 1 RIB43A Ribosomal_L21p PF00829.16 KKK17714.1 - 0.047 13.8 0.0 0.17 12.0 0.0 1.9 1 1 1 2 2 2 0 Ribosomal prokaryotic L21 protein DUF605 PF04652.11 KKK17714.1 - 0.12 11.7 9.3 0.16 11.3 6.5 1.1 1 0 0 1 1 1 0 Vta1 like Mucin PF01456.12 KKK17714.1 - 1.3 8.7 9.6 2.1 8.0 6.7 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein ORC6 PF05460.8 KKK17714.1 - 1.8 7.5 9.7 2.7 7.0 6.7 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) DUF822 PF05687.8 KKK17714.1 - 6.3 7.1 9.1 3.5 7.9 0.2 2.2 2 0 0 2 2 2 0 Plant protein of unknown function (DUF822) DUF1338 PF07063.8 KKK17715.1 - 4.1e-94 315.0 0.2 5.2e-94 314.6 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1338) Slx4 PF09494.5 KKK17715.1 - 0.064 13.0 0.0 0.45 10.3 0.0 2.5 2 0 0 2 2 2 0 Slx4 endonuclease OB_NTP_bind PF07717.11 KKK17719.1 - 1.9e-29 101.7 0.0 5.3e-29 100.3 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 KKK17719.1 - 6.6e-26 90.3 0.1 4.5e-25 87.6 0.0 2.6 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 KKK17719.1 - 1.8e-12 46.9 0.0 5.1e-12 45.4 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KKK17719.1 - 2.8e-07 30.1 0.1 7e-07 28.8 0.1 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KKK17719.1 - 5.1e-05 23.4 0.0 0.00016 21.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 KKK17719.1 - 6.6e-05 21.9 0.0 0.00014 20.8 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein SRP54 PF00448.17 KKK17719.1 - 0.0085 15.5 0.1 0.02 14.3 0.0 1.7 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_19 PF13245.1 KKK17719.1 - 0.012 15.3 0.1 0.088 12.5 0.1 2.5 2 0 0 2 2 2 0 Part of AAA domain Sigma54_activ_2 PF14532.1 KKK17719.1 - 0.097 12.7 0.0 0.31 11.0 0.0 1.9 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_29 PF13555.1 KKK17719.1 - 0.11 11.9 0.0 0.3 10.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 KKK17719.1 - 0.21 11.8 2.2 0.85 9.9 0.1 2.7 1 1 1 2 2 2 0 ABC transporter Mannitol_dh PF01232.18 KKK17719.1 - 0.22 11.4 1.2 0.73 9.7 0.1 2.3 2 0 0 2 2 2 0 Mannitol dehydrogenase Rossmann domain AAA_23 PF13476.1 KKK17719.1 - 0.24 11.7 0.0 0.24 11.7 0.0 3.6 1 1 2 3 3 1 0 AAA domain Cyt-b5 PF00173.23 KKK17720.1 - 5e-19 67.8 0.0 5.5e-19 67.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain VHS PF00790.14 KKK17721.1 - 9e-24 83.7 0.0 1.8e-23 82.7 0.0 1.5 1 0 0 1 1 1 1 VHS domain GAT PF03127.9 KKK17721.1 - 1.8e-11 43.8 1.4 3.5e-11 42.9 1.0 1.4 1 0 0 1 1 1 1 GAT domain ubiquitin PF00240.18 KKK17721.1 - 0.0071 15.7 0.0 0.02 14.2 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin family ENTH PF01417.15 KKK17721.1 - 0.013 15.4 0.0 0.033 14.0 0.0 1.6 1 0 0 1 1 1 0 ENTH domain Pantoate_transf PF02548.10 KKK17722.1 - 7.4e-107 356.3 0.9 8.7e-107 356.0 0.6 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.1 KKK17722.1 - 1.2e-09 37.7 0.7 2.9e-09 36.5 0.5 1.7 1 1 0 1 1 1 1 Phosphoenolpyruvate phosphomutase APG12 PF04110.8 KKK17723.1 - 1.2e-30 105.5 0.0 2.2e-30 104.6 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.11 KKK17723.1 - 0.046 13.6 0.0 0.06 13.3 0.0 1.2 1 0 0 1 1 1 0 Autophagy protein Atg8 ubiquitin like UQ_con PF00179.21 KKK17724.1 - 2e-35 121.2 0.1 2.4e-35 121.0 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme LAMTOR PF15454.1 KKK17725.1 - 1e-24 86.5 0.4 1.7e-24 85.8 0.3 1.4 1 0 0 1 1 1 1 Late endosomal/lysosomal adaptor and MAPK and MTOR activator SOG2 PF10428.4 KKK17725.1 - 0.12 11.0 0.3 0.13 10.8 0.2 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein DUF2011 PF09428.5 KKK17726.1 - 6.5e-45 152.2 3.4 1.1e-44 151.4 2.3 1.4 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2011) MFS_1 PF07690.11 KKK17727.1 - 2.5e-44 151.4 44.5 3.7e-44 150.8 30.1 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KKK17727.1 - 6.4e-16 57.9 34.4 1.2e-15 57.1 8.5 3.8 3 1 0 3 3 3 2 Sugar (and other) transporter DUF3624 PF12292.3 KKK17727.1 - 3.3 8.1 8.2 0.26 11.6 0.9 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3624) Flavoprotein PF02441.14 KKK17728.1 - 1.3e-11 44.3 0.0 2.4e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 Flavoprotein Ribonuc_red_sm PF00268.16 KKK17729.1 - 6.1e-121 402.7 1.3 7.3e-121 402.4 0.9 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain SRP9-21 PF05486.7 KKK17730.1 - 4.6e-32 109.5 0.2 7e-32 109.0 0.1 1.3 1 0 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) Pol_alpha_B_N PF08418.5 KKK17730.1 - 0.53 9.7 6.0 0.73 9.3 4.2 1.3 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal WD40 PF00400.27 KKK17731.1 - 1.3e-14 53.4 12.0 1.3e-08 34.4 0.6 6.0 7 0 0 7 7 7 3 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 KKK17731.1 - 0.0012 17.2 0.0 1.7 6.8 0.0 3.2 2 1 1 3 3 3 2 Cytochrome D1 heme domain MRG PF05712.8 KKK17731.1 - 0.048 12.5 0.3 0.095 11.5 0.2 1.4 1 1 0 1 1 1 0 MRG DUF4613 PF15390.1 KKK17731.1 - 0.067 11.3 0.5 0.11 10.6 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4613) DUF3312 PF11768.3 KKK17731.1 - 0.093 10.9 0.0 0.14 10.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3312) DUF1513 PF07433.6 KKK17731.1 - 0.094 11.5 0.4 0.6 8.9 0.0 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1513) Mito_carr PF00153.22 KKK17732.1 - 2e-58 194.0 4.1 1.2e-20 73.0 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein TruB_N PF01509.13 KKK17734.1 - 8.8e-47 159.0 0.0 3.6e-46 156.9 0.0 2.0 2 0 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) vMSA PF00695.14 KKK17734.1 - 0.89 8.6 5.3 1.4 8.0 3.7 1.2 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus WD40 PF00400.27 KKK17735.1 - 1.4e-31 107.1 8.9 1.9e-07 30.6 0.0 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat BBS2_Mid PF14783.1 KKK17735.1 - 0.0034 17.1 0.0 6 6.6 0.0 3.8 4 2 1 5 5 5 2 Ciliary BBSome complex subunit 2, middle region RicinB_lectin_2 PF14200.1 KKK17735.1 - 0.11 12.9 0.1 22 5.4 0.0 3.3 2 1 1 3 3 3 0 Ricin-type beta-trefoil lectin domain-like OHCU_decarbox PF09349.5 KKK17736.1 - 3.9e-49 166.9 0.0 4.4e-49 166.8 0.0 1.0 1 0 0 1 1 1 1 OHCU decarboxylase Ebp2 PF05890.7 KKK17738.1 - 8.8e-97 323.6 11.8 8.8e-97 323.6 8.2 2.1 1 1 1 2 2 2 1 Eukaryotic rRNA processing protein EBP2 Response_reg PF00072.19 KKK17739.1 - 0.013 15.4 0.0 0.023 14.6 0.0 1.3 1 0 0 1 1 1 0 Response regulator receiver domain PqiA PF04403.8 KKK17739.1 - 0.34 10.4 9.7 0.67 9.5 6.7 1.4 1 0 0 1 1 1 0 Paraquat-inducible protein A AMP-binding PF00501.23 KKK17740.1 - 1.3e-69 234.5 0.0 1.9e-69 234.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KKK17740.1 - 1.3e-14 54.8 0.2 7.7e-14 52.3 0.0 2.2 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain MeMO_Hyd_G PF02964.11 KKK17741.1 - 0.0034 17.3 0.0 0.0058 16.5 0.0 1.3 1 0 0 1 1 1 1 Methane monooxygenase, hydrolase gamma chain adh_short PF00106.20 KKK17742.1 - 0.00019 21.4 0.1 0.00019 21.4 0.1 1.7 2 1 0 2 2 2 1 short chain dehydrogenase LDB19 PF13002.2 KKK17743.1 - 2.9e-59 199.7 0.0 4.6e-59 199.1 0.0 1.3 1 0 0 1 1 1 1 Arrestin_N terminal like Arrestin_N PF00339.24 KKK17743.1 - 2.1e-08 34.0 0.0 7.4e-08 32.3 0.0 1.9 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain DUF4606 PF15379.1 KKK17743.1 - 0.094 12.7 0.0 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4606) SASRP1 PF15160.1 KKK17743.1 - 1.5 7.9 8.7 0.2 10.8 2.6 1.8 2 0 0 2 2 2 0 Spermatogenesis-associated serine-rich protein 1 DIOX_N PF14226.1 KKK17744.1 - 8.8e-26 90.7 0.0 1.4e-25 90.1 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KKK17744.1 - 7.3e-17 61.4 0.0 3.4e-16 59.3 0.0 2.0 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Amidohydro_2 PF04909.9 KKK17745.1 - 8.7e-36 123.8 2.8 2.2e-35 122.5 2.0 1.6 1 1 0 1 1 1 1 Amidohydrolase TatD_DNase PF01026.16 KKK17745.1 - 0.0082 15.3 0.0 0.016 14.4 0.0 1.4 1 0 0 1 1 1 1 TatD related DNase DIOX_N PF14226.1 KKK17746.1 - 3e-19 69.6 0.0 4.6e-19 69.0 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KKK17746.1 - 3.3e-12 46.5 0.1 3e-11 43.4 0.0 2.2 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MKT1_C PF12246.3 KKK17747.1 - 7e-75 251.1 0.0 1.1e-74 250.5 0.0 1.3 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication Thioredoxin PF00085.15 KKK17747.1 - 4.1e-61 203.1 0.5 9e-31 105.6 0.0 3.3 3 0 0 3 3 3 2 Thioredoxin MKT1_N PF12247.3 KKK17747.1 - 2.1e-32 111.2 0.1 5.5e-32 109.9 0.0 1.8 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication ERp29 PF07749.7 KKK17747.1 - 8.6e-21 74.3 2.1 1.2e-20 73.9 0.5 2.1 2 0 0 2 2 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_2 PF13098.1 KKK17747.1 - 3.8e-18 65.7 0.4 1.3e-07 31.7 0.0 3.6 4 0 0 4 4 3 2 Thioredoxin-like domain XPG_I PF00867.13 KKK17747.1 - 1.4e-15 57.1 0.1 5.1e-15 55.2 0.0 2.1 2 0 0 2 2 2 1 XPG I-region Thioredoxin_7 PF13899.1 KKK17747.1 - 4.8e-13 48.9 0.0 1.3e-06 28.2 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_8 PF13905.1 KKK17747.1 - 2e-12 47.0 0.3 0.00011 22.2 0.0 3.8 3 1 1 4 4 4 2 Thioredoxin-like AhpC-TSA PF00578.16 KKK17747.1 - 5.8e-07 29.2 0.1 0.05 13.2 0.0 2.7 2 0 0 2 2 2 2 AhpC/TSA family Redoxin PF08534.5 KKK17747.1 - 5.3e-06 26.0 0.1 0.026 14.0 0.0 2.9 2 0 0 2 2 2 2 Redoxin XPG_N PF00752.12 KKK17747.1 - 2e-05 24.7 0.0 5.8e-05 23.2 0.0 1.8 1 0 0 1 1 1 1 XPG N-terminal domain Thioredoxin_9 PF14595.1 KKK17747.1 - 0.0066 16.0 0.0 2.5 7.6 0.0 2.5 2 0 0 2 2 2 1 Thioredoxin HyaE PF07449.6 KKK17747.1 - 0.061 13.2 0.0 1.7 8.5 0.0 2.5 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE Thioredoxin_4 PF13462.1 KKK17747.1 - 0.26 11.2 5.6 8.4 6.3 0.0 4.0 3 2 2 5 5 5 0 Thioredoxin HSBP1 PF06825.7 KKK17748.1 - 1.6e-18 66.0 0.1 2.1e-18 65.6 0.1 1.1 1 0 0 1 1 1 1 Heat shock factor binding protein 1 Matrilin_ccoil PF10393.4 KKK17748.1 - 3.4e-05 23.1 0.9 0.1 11.9 0.1 2.1 1 1 1 2 2 2 2 Trimeric coiled-coil oligomerisation domain of matrilin DUF2937 PF11157.3 KKK17748.1 - 0.0024 17.2 0.1 0.0027 17.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2937) DUF1932 PF09130.6 KKK17748.1 - 0.0025 17.5 0.1 0.0088 15.7 0.0 1.8 1 1 1 2 2 2 1 Domain of unknown function (DUF1932) NPV_P10 PF05531.7 KKK17748.1 - 0.01 16.0 0.1 0.013 15.7 0.1 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Baculo_PEP_C PF04513.7 KKK17748.1 - 0.011 15.6 0.1 0.012 15.4 0.1 1.1 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Apolipoprotein PF01442.13 KKK17748.1 - 0.025 14.0 0.0 0.028 13.9 0.0 1.1 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain SPX PF03105.14 KKK17748.1 - 0.054 13.2 0.0 0.059 13.1 0.0 1.0 1 0 0 1 1 1 0 SPX domain DUF1664 PF07889.7 KKK17748.1 - 0.06 13.1 0.0 0.069 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) PilJ PF13675.1 KKK17748.1 - 0.06 13.6 0.2 0.069 13.4 0.1 1.1 1 0 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term Corona_S2 PF01601.11 KKK17748.1 - 0.065 11.3 0.1 0.078 11.0 0.1 1.0 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein Tup_N PF08581.5 KKK17748.1 - 0.08 13.1 0.1 0.13 12.4 0.1 1.4 1 0 0 1 1 1 0 Tup N-terminal KfrA_N PF11740.3 KKK17748.1 - 0.16 12.3 0.1 0.16 12.3 0.1 1.4 2 0 0 2 2 1 0 Plasmid replication region DNA-binding N-term UPF0184 PF03670.8 KKK17748.1 - 0.19 11.9 0.8 0.4 10.9 0.5 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0184) DUF1308 PF07000.6 KKK17749.1 - 7.5e-103 343.9 0.0 1.2e-102 343.2 0.0 1.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1308) Lung_7-TM_R PF06814.8 KKK17750.1 - 2.8e-71 239.9 15.3 3.3e-71 239.6 10.6 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor DUF4112 PF13430.1 KKK17751.1 - 1.1e-33 115.2 0.4 1.4e-33 114.9 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) DCP2 PF05026.8 KKK17752.1 - 4e-36 122.7 1.1 6.7e-36 122.0 0.8 1.4 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.23 KKK17752.1 - 7.3e-16 58.0 0.0 1.5e-15 57.0 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain SNAP-25 PF00835.14 KKK17753.1 - 0.11 13.3 0.3 0.19 12.4 0.2 1.4 1 0 0 1 1 1 0 SNAP-25 family DUF2392 PF10288.4 KKK17754.1 - 5.2e-27 94.2 0.0 9.4e-27 93.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2392) FYVE PF01363.16 KKK17754.1 - 0.25 11.2 6.6 0.15 11.9 0.7 2.3 2 0 0 2 2 2 0 FYVE zinc finger DnaJ PF00226.26 KKK17755.1 - 1.2e-19 69.7 0.6 3.7e-19 68.2 0.4 1.9 1 0 0 1 1 1 1 DnaJ domain RRM_1 PF00076.17 KKK17755.1 - 0.036 13.7 0.1 0.14 11.8 0.0 2.0 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KKK17755.1 - 0.17 11.7 0.0 0.41 10.5 0.0 1.7 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Homez PF11569.3 KKK17756.1 - 0.0074 15.3 0.2 0.017 14.1 0.1 1.5 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez Mei4 PF13971.1 KKK17756.1 - 0.042 12.8 6.5 0.76 8.6 4.5 2.5 1 1 0 1 1 1 0 Meiosis-specific protein Mei4 R3H-assoc PF13902.1 KKK17756.1 - 0.063 13.2 1.3 1.3 8.9 0.3 2.4 2 0 0 2 2 2 0 R3H-associated N-terminal domain Striatin PF08232.7 KKK17756.1 - 0.42 10.9 6.4 0.68 10.2 1.5 2.8 3 0 0 3 3 3 0 Striatin family GCV_T PF01571.16 KKK17757.1 - 2.8e-15 56.2 0.0 5.9e-15 55.2 0.0 1.5 1 1 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 KKK17757.1 - 0.00098 19.1 0.0 0.0022 17.9 0.0 1.7 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain V_ATPase_I PF01496.14 KKK17790.1 - 2.9e-297 987.7 0.2 3.2e-297 987.5 0.1 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family DUF1515 PF07439.6 KKK17790.1 - 0.0055 16.5 0.1 0.015 15.1 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1515) DUF3552 PF12072.3 KKK17790.1 - 0.03 13.5 1.5 5.7 6.0 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) Serine_rich PF08824.5 KKK17790.1 - 0.04 13.6 1.0 0.19 11.4 0.1 2.1 2 0 0 2 2 2 0 Serine rich protein interaction domain Filament PF00038.16 KKK17790.1 - 0.07 12.5 7.6 2.8 7.3 0.1 2.4 2 1 0 2 2 2 0 Intermediate filament protein YlqD PF11068.3 KKK17790.1 - 0.17 11.9 1.3 2.9 7.9 0.2 2.5 2 0 0 2 2 2 0 YlqD protein CheZ PF04344.8 KKK17790.1 - 0.21 11.2 0.1 0.21 11.2 0.1 2.4 3 0 0 3 3 3 0 Chemotaxis phosphatase, CheZ Prefoldin_2 PF01920.15 KKK17790.1 - 0.37 10.5 2.9 1.2 8.8 0.2 2.7 3 0 0 3 3 3 0 Prefoldin subunit FliD_C PF07195.7 KKK17790.1 - 0.41 9.8 3.8 0.83 8.8 0.3 2.2 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus DUF869 PF05911.6 KKK17790.1 - 0.45 8.6 4.7 2.7 6.1 3.2 1.8 1 1 0 1 1 1 0 Plant protein of unknown function (DUF869) IncA PF04156.9 KKK17790.1 - 1.3 8.5 5.0 0.94 9.0 1.3 2.1 2 0 0 2 2 2 0 IncA protein DivIC PF04977.10 KKK17790.1 - 3.8 7.0 7.0 0.41 10.1 0.3 2.8 3 0 0 3 3 3 0 Septum formation initiator BioY PF02632.9 KKK17790.1 - 7.1 6.2 13.2 0.23 11.1 0.3 2.8 3 0 0 3 3 3 0 BioY family ECH PF00378.15 KKK17791.1 - 4.8e-45 153.5 0.0 5.4e-45 153.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family ECH_C PF13766.1 KKK17791.1 - 0.023 14.8 0.0 0.049 13.7 0.0 1.6 1 1 0 1 1 1 0 2-enoyl-CoA Hydratase C-terminal region AMP-binding PF00501.23 KKK17792.1 - 7.5e-83 278.2 0.0 3.2e-77 259.6 0.0 2.3 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.15 KKK17792.1 - 4.2e-74 249.1 4.1 1e-36 126.3 0.0 3.6 4 0 0 4 4 4 2 Condensation domain PP-binding PF00550.20 KKK17792.1 - 2e-28 98.4 0.1 1.3e-12 47.8 0.0 3.3 3 0 0 3 3 3 2 Phosphopantetheine attachment site AMP-binding_C PF13193.1 KKK17792.1 - 4.5e-08 33.9 0.3 0.0045 17.9 0.1 3.5 3 0 0 3 3 3 2 AMP-binding enzyme C-terminal domain DUF553 PF04473.7 KKK17792.1 - 0.16 11.2 0.0 0.34 10.1 0.0 1.4 1 0 0 1 1 1 0 Transglutaminase-like domain AATase PF07247.7 KKK17792.1 - 0.17 10.4 2.9 4.1 5.8 0.0 2.6 3 0 0 3 3 3 0 Alcohol acetyltransferase Pro_CA PF00484.14 KKK17793.1 - 1e-29 103.4 0.0 6.4e-14 52.2 0.0 2.2 2 0 0 2 2 2 2 Carbonic anhydrase AMP-binding PF00501.23 KKK17794.1 - 1.2e-71 241.3 0.0 2.6e-71 240.1 0.0 1.6 2 0 0 2 2 2 1 AMP-binding enzyme NAD_binding_4 PF07993.7 KKK17794.1 - 2.8e-57 193.5 0.0 2.7e-55 187.0 0.0 2.3 1 1 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 KKK17794.1 - 5.9e-16 58.6 0.0 1.2e-15 57.6 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 KKK17794.1 - 2.4e-11 43.7 0.0 5.2e-11 42.6 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.1 KKK17794.1 - 3.5e-08 34.2 0.0 1.5e-07 32.2 0.0 2.2 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain 3Beta_HSD PF01073.14 KKK17794.1 - 2.6e-07 29.6 0.1 5.5e-07 28.5 0.0 1.6 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 KKK17794.1 - 0.00034 19.6 0.1 0.038 12.8 0.0 2.5 2 0 0 2 2 2 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 KKK17794.1 - 0.0013 18.7 0.0 0.0035 17.3 0.0 1.8 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 KKK17794.1 - 0.0031 17.4 0.3 0.01 15.7 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase Condensation PF00668.15 KKK17794.1 - 0.0038 16.1 0.0 0.0068 15.2 0.0 1.3 1 0 0 1 1 1 1 Condensation domain Polysacc_synt_2 PF02719.10 KKK17794.1 - 0.16 10.8 0.0 0.3 9.9 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Mannosyl_trans2 PF04188.8 KKK17795.1 - 4.9e-57 193.7 21.4 9.5e-57 192.8 14.8 1.3 1 0 0 1 1 1 1 Mannosyltransferase (PIG-V)) DUF3437 PF11919.3 KKK17795.1 - 7.6e-32 108.8 0.0 2.7e-31 107.1 0.0 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3437) CLASP_N PF12348.3 KKK17795.1 - 2.8e-06 26.8 0.1 0.031 13.6 0.0 3.2 4 0 0 4 4 4 2 CLASP N terminal HEAT PF02985.17 KKK17795.1 - 0.0046 16.9 0.4 1.6 8.9 0.0 4.6 4 0 0 4 4 4 1 HEAT repeat Adaptin_N PF01602.15 KKK17795.1 - 0.23 9.7 0.0 0.61 8.3 0.0 1.6 1 0 0 1 1 1 0 Adaptin N terminal region Oxidored-like PF09791.4 KKK17797.1 - 3.7e-25 87.1 3.4 7.5e-25 86.1 2.3 1.5 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal Ribosomal_L13e PF01294.13 KKK17799.1 - 7.3e-47 159.1 2.2 4e-46 156.7 1.5 2.3 1 1 0 1 1 1 1 Ribosomal protein L13e IncA PF04156.9 KKK17799.1 - 1.3 8.6 7.0 2.8 7.4 4.8 1.5 1 0 0 1 1 1 0 IncA protein GCIP PF13324.1 KKK17800.1 - 1.6e-11 43.9 1.2 2.2e-11 43.5 0.9 1.1 1 0 0 1 1 1 1 Grap2 and cyclin-D-interacting CDC45 PF02724.9 KKK17800.1 - 0.0021 16.2 2.1 0.0023 16.0 1.5 1.1 1 0 0 1 1 1 1 CDC45-like protein Sigma70_ner PF04546.8 KKK17800.1 - 0.0059 16.2 6.2 0.0092 15.6 4.3 1.4 1 0 0 1 1 1 1 Sigma-70, non-essential region Nop14 PF04147.7 KKK17800.1 - 0.0073 14.2 9.3 0.0086 14.0 6.5 1.1 1 0 0 1 1 1 1 Nop14-like family Pox_RNA_Pol_19 PF05320.7 KKK17800.1 - 0.052 13.2 3.4 0.089 12.5 2.4 1.4 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit Vfa1 PF08432.5 KKK17800.1 - 0.077 13.0 5.0 0.12 12.3 3.5 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 TRAP_alpha PF03896.11 KKK17800.1 - 0.31 9.9 5.9 0.41 9.5 4.1 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit CobT PF06213.7 KKK17800.1 - 0.46 9.5 12.7 0.72 8.9 8.8 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT RRN3 PF05327.6 KKK17800.1 - 0.47 8.4 4.5 0.54 8.3 3.1 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 FAM176 PF14851.1 KKK17800.1 - 0.5 10.0 3.8 0.93 9.1 2.6 1.4 1 0 0 1 1 1 0 FAM176 family SDA1 PF05285.7 KKK17800.1 - 0.55 9.4 14.3 0.67 9.1 9.9 1.1 1 0 0 1 1 1 0 SDA1 PI3K_1B_p101 PF10486.4 KKK17800.1 - 1.1 6.7 3.1 1.2 6.6 2.2 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Sporozoite_P67 PF05642.6 KKK17800.1 - 1.3 6.7 5.8 2 6.1 4.0 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Myc_N PF01056.13 KKK17800.1 - 1.9 7.6 7.2 2.7 7.0 5.0 1.3 1 0 0 1 1 1 0 Myc amino-terminal region DUF2890 PF11081.3 KKK17800.1 - 2.1 8.3 13.3 3.7 7.5 9.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) NOA36 PF06524.7 KKK17800.1 - 2.6 7.2 12.6 3.8 6.6 8.7 1.2 1 0 0 1 1 1 0 NOA36 protein Bac_surface_Ag PF01103.18 KKK17802.1 - 2.6e-36 125.7 0.1 4.1e-36 125.0 0.1 1.2 1 0 0 1 1 1 1 Surface antigen Yip1 PF04893.12 KKK17802.1 - 5e-05 22.8 18.5 0.00078 18.9 6.3 2.4 2 0 0 2 2 2 2 Yip1 domain Sporozoite_P67 PF05642.6 KKK17802.1 - 5.9 4.6 7.2 10 3.8 5.0 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen AAA PF00004.24 KKK17803.1 - 1.2e-43 148.4 0.0 2.1e-43 147.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KKK17803.1 - 2e-08 34.0 0.0 4.6e-08 32.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 KKK17803.1 - 1.1e-07 31.9 0.0 2.1e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 KKK17803.1 - 2.3e-06 27.7 0.1 1.3e-05 25.2 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KKK17803.1 - 3.9e-06 27.0 0.1 0.00023 21.2 0.1 2.5 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KKK17803.1 - 9.9e-05 23.1 0.0 0.00023 21.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 KKK17803.1 - 0.00013 21.1 0.0 0.00024 20.2 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 KKK17803.1 - 0.00013 21.6 0.1 0.00028 20.5 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 KKK17803.1 - 0.00039 19.8 0.0 0.00073 19.0 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.8 KKK17803.1 - 0.0011 17.7 0.0 0.0021 16.8 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.1 KKK17803.1 - 0.0016 18.3 0.0 0.0032 17.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KKK17803.1 - 0.0021 17.9 0.0 0.0035 17.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KKK17803.1 - 0.0026 16.8 0.0 0.0047 16.0 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_28 PF13521.1 KKK17803.1 - 0.0038 17.1 0.0 0.0066 16.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.6 KKK17803.1 - 0.0039 16.7 0.0 0.011 15.3 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.16 KKK17803.1 - 0.0041 16.3 0.1 0.015 14.4 0.0 1.9 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI KaiC PF06745.8 KKK17803.1 - 0.0054 15.8 0.0 0.017 14.2 0.0 1.8 2 0 0 2 2 2 1 KaiC AAA_18 PF13238.1 KKK17803.1 - 0.0061 16.8 0.0 0.028 14.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 KKK17803.1 - 0.019 14.3 0.1 0.066 12.6 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.1 KKK17803.1 - 0.02 14.5 0.0 0.037 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 KKK17803.1 - 0.02 14.1 0.0 0.076 12.2 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein Sigma54_activat PF00158.21 KKK17803.1 - 0.02 14.3 0.1 0.096 12.1 0.0 2.1 2 1 0 2 2 2 0 Sigma-54 interaction domain DUF815 PF05673.8 KKK17803.1 - 0.02 13.8 0.0 0.037 12.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) DUF2072 PF09845.4 KKK17803.1 - 0.028 14.3 0.3 0.075 12.9 0.1 1.8 2 0 0 2 2 1 0 Zn-ribbon containing protein (DUF2072) RNA_helicase PF00910.17 KKK17803.1 - 0.033 14.3 0.0 0.066 13.4 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Sigma54_activ_2 PF14532.1 KKK17803.1 - 0.047 13.7 0.0 0.15 12.1 0.0 2.0 1 1 0 1 1 1 0 Sigma-54 interaction domain Parvo_NS1 PF01057.12 KKK17803.1 - 0.05 12.4 0.0 0.083 11.7 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NACHT PF05729.7 KKK17803.1 - 0.068 12.8 0.0 0.53 9.9 0.0 2.1 1 1 0 2 2 2 0 NACHT domain NB-ARC PF00931.17 KKK17803.1 - 0.079 11.8 0.0 0.15 10.8 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Histone PF00125.19 KKK17803.1 - 0.097 12.8 0.0 0.29 11.2 0.0 1.8 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 FGGY_C PF02782.11 KKK17804.1 - 3.4e-50 170.4 0.1 6.1e-50 169.5 0.1 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 KKK17804.1 - 7.4e-25 87.6 0.1 9.3e-24 84.0 0.1 2.2 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.15 KKK17804.1 - 0.01 15.1 0.0 0.039 13.2 0.0 1.9 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family Na_Ca_ex PF01699.19 KKK17805.1 - 4.1e-30 104.2 23.9 7.7e-18 64.4 6.8 4.5 6 0 0 6 6 6 2 Sodium/calcium exchanger protein DUF307 PF03733.8 KKK17805.1 - 1.1e-14 54.5 12.3 1.1e-14 54.5 8.5 3.9 3 0 0 3 3 3 1 Domain of unknown function (DUF307) TFIIA PF03153.8 KKK17805.1 - 0.42 10.4 15.0 0.82 9.5 10.4 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Tom22 PF04281.8 KKK17805.1 - 0.68 9.4 3.5 1.9 8.0 2.4 1.7 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 Nop14 PF04147.7 KKK17805.1 - 9.2 4.0 15.6 14 3.4 10.8 1.1 1 0 0 1 1 1 0 Nop14-like family UFD1 PF03152.9 KKK17806.1 - 3.7e-24 84.8 0.0 5.3e-19 68.0 0.0 3.3 2 1 0 2 2 2 2 Ubiquitin fusion degradation protein UFD1 zinc_ribbon_5 PF13719.1 KKK17806.1 - 0.15 11.6 4.2 13 5.4 0.0 3.7 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 KKK17806.1 - 0.17 11.5 4.3 9.5 6.0 0.0 3.7 3 0 0 3 3 3 0 zinc-ribbon domain K_channel_TID PF07941.6 KKK17806.1 - 0.73 10.1 8.9 30 4.9 4.2 3.0 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain CAF-1_p150 PF11600.3 KKK17806.1 - 1.7 8.0 8.7 5.7 6.2 0.4 2.4 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal BNIP3 PF06553.7 KKK17806.1 - 6.2 6.1 10.5 4.1 6.7 0.4 2.5 2 0 0 2 2 2 0 BNIP3 ABC1 PF03109.11 KKK17808.1 - 8.1e-24 83.8 0.0 9.3e-14 51.4 0.0 2.8 3 0 0 3 3 3 2 ABC1 family RIO1 PF01163.17 KKK17808.1 - 0.034 13.4 0.0 0.61 9.4 0.0 2.2 2 0 0 2 2 2 0 RIO1 family APH PF01636.18 KKK17808.1 - 0.06 13.0 0.0 0.15 11.7 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family Cyto_heme_lyase PF01265.12 KKK17809.1 - 3e-82 276.0 0.0 3.5e-82 275.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase ATP-grasp_2 PF08442.5 KKK17811.1 - 1.5e-77 259.5 0.3 1.5e-77 259.5 0.2 1.6 2 0 0 2 2 2 1 ATP-grasp domain Ligase_CoA PF00549.14 KKK17811.1 - 3.4e-25 88.4 0.3 3.4e-25 88.4 0.2 1.8 2 0 0 2 2 2 1 CoA-ligase ATP-grasp_5 PF13549.1 KKK17811.1 - 1.8e-08 33.8 0.3 4.6e-08 32.5 0.2 1.7 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.14 KKK17811.1 - 0.00011 21.8 1.6 0.005 16.4 0.1 2.7 2 1 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Peripla_BP_2 PF01497.13 KKK17811.1 - 0.0045 16.1 0.2 0.0098 15.0 0.2 1.5 1 0 0 1 1 1 1 Periplasmic binding protein Succ_CoA_lig PF13607.1 KKK17811.1 - 0.0097 15.5 0.3 7.5 6.1 0.0 3.2 2 1 1 3 3 3 2 Succinyl-CoA ligase like flavodoxin domain ATP-grasp_4 PF13535.1 KKK17811.1 - 0.11 12.2 0.0 0.24 11.1 0.0 1.7 1 0 0 1 1 1 0 ATP-grasp domain adh_short PF00106.20 KKK17812.1 - 7.4e-16 58.5 0.2 7.2e-09 35.7 0.0 2.3 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.1 KKK17812.1 - 1.7e-12 47.6 0.0 4.2e-12 46.3 0.0 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 KKK17812.1 - 0.00056 19.1 0.0 0.0015 17.7 0.0 1.6 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) NmrA PF05368.8 KKK17812.1 - 0.0075 15.5 0.1 0.036 13.3 0.0 2.0 3 0 0 3 3 3 1 NmrA-like family KR PF08659.5 KKK17812.1 - 0.013 15.2 0.2 0.15 11.7 0.0 2.2 2 0 0 2 2 2 0 KR domain NAD_binding_10 PF13460.1 KKK17812.1 - 0.027 14.4 0.0 0.044 13.7 0.0 1.4 1 0 0 1 1 1 0 NADH(P)-binding ADH_zinc_N PF00107.21 KKK17812.1 - 0.032 13.7 0.1 0.54 9.8 0.0 2.1 2 0 0 2 2 2 0 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 KKK17812.1 - 0.048 12.8 0.0 0.087 11.9 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UQ_con PF00179.21 KKK17813.1 - 6.2e-26 90.4 0.1 8.7e-26 90.0 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme SLAC1 PF03595.12 KKK17814.1 - 2.3e-75 253.2 49.5 2.6e-75 253.0 34.3 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel COX14 PF14880.1 KKK17814.1 - 0.13 11.9 0.2 0.13 11.9 0.1 2.4 2 0 0 2 2 2 0 Cytochrome oxidase c assembly Pribosyltran PF00156.22 KKK17815.1 - 1.9e-08 34.0 0.1 6.4e-08 32.3 0.0 1.8 1 1 0 1 1 1 1 Phosphoribosyl transferase domain DPM3 PF08285.6 KKK17816.1 - 8.7e-30 102.4 0.7 2.7e-28 97.6 0.0 2.0 2 0 0 2 2 2 2 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) HSF_DNA-bind PF00447.12 KKK17817.1 - 7.6e-36 122.4 0.6 1.2e-35 121.7 0.4 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding DUF3245 PF11595.3 KKK17818.1 - 4.8e-53 179.4 7.3 4.8e-53 179.4 5.0 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF3245) Vac7 PF12751.2 KKK17818.1 - 0.0072 15.2 2.4 0.0081 15.0 1.6 1.3 1 0 0 1 1 1 1 Vacuolar segregation subunit 7 Myc_N PF01056.13 KKK17818.1 - 0.32 10.1 2.3 0.42 9.7 0.6 1.9 2 0 0 2 2 2 0 Myc amino-terminal region LRR_4 PF12799.2 KKK17819.1 - 4.1e-35 118.8 40.2 4e-11 42.2 1.2 9.7 7 2 2 9 9 9 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KKK17819.1 - 2.6e-25 87.9 34.0 2.1e-07 30.5 0.5 7.9 6 2 3 9 9 9 8 Leucine rich repeat LRR_1 PF00560.28 KKK17819.1 - 2.6e-17 60.1 40.0 0.063 13.3 0.2 14.1 14 2 0 14 14 14 6 Leucine Rich Repeat LRR_7 PF13504.1 KKK17819.1 - 3.5e-15 53.4 36.2 0.31 11.3 0.1 14.0 15 0 0 15 15 15 5 Leucine rich repeat LRR_6 PF13516.1 KKK17819.1 - 2.3e-10 39.4 27.2 1.1 9.4 0.0 11.4 13 0 0 13 13 13 5 Leucine Rich repeat LRR_9 PF14580.1 KKK17819.1 - 0.27 10.7 8.5 2.3 7.7 0.9 3.3 2 2 2 4 4 4 0 Leucine-rich repeat Pkinase PF00069.20 KKK17850.1 - 1.4e-41 142.3 0.0 2.4e-41 141.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK17850.1 - 4.4e-24 84.9 0.0 7e-24 84.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 KKK17850.1 - 0.69 8.6 0.0 1 8.1 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase K_oxygenase PF13434.1 KKK17851.1 - 2.1e-107 358.9 0.0 2.7e-107 358.6 0.0 1.1 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.1 KKK17851.1 - 1.8e-11 44.4 0.0 7.2e-09 36.0 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KKK17851.1 - 6.7e-08 32.4 0.1 6.4e-06 26.0 0.0 3.0 2 1 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 KKK17851.1 - 0.00019 21.4 0.0 0.022 14.6 0.0 2.5 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DUF4147 PF13660.1 KKK17851.1 - 0.045 12.8 0.0 6.1 5.8 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4147) BNR_2 PF13088.1 KKK17858.1 - 9e-09 35.0 0.2 1.6e-05 24.3 0.1 3.5 1 1 2 3 3 3 2 BNR repeat-like domain BNR PF02012.15 KKK17858.1 - 5.2e-06 25.4 15.2 0.17 11.8 0.2 5.1 5 0 0 5 5 5 4 BNR/Asp-box repeat Extensin_1 PF02095.10 KKK17859.1 - 0.98 9.5 5.6 0.23 11.5 1.3 2.0 2 0 0 2 2 2 0 Extensin-like protein repeat Peptidase_S64 PF08192.6 KKK17863.1 - 0.88 7.8 18.5 1.1 7.4 12.8 1.1 1 0 0 1 1 1 0 Peptidase family S64 Mitofilin PF09731.4 KKK17863.1 - 3.4 6.2 9.8 4.4 5.8 6.8 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein HAD_2 PF13419.1 KKK17864.1 - 3.4e-11 43.6 0.0 0.00042 20.5 0.0 2.9 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KKK17864.1 - 0.0017 18.0 0.0 0.0032 17.1 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like NAD_binding_8 PF13450.1 KKK17865.1 - 7.6e-08 32.2 0.7 1.2e-07 31.6 0.5 1.3 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 KKK17865.1 - 4.1e-06 26.1 0.2 4.5e-06 25.9 0.1 1.0 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 KKK17865.1 - 0.00018 20.5 1.6 0.0022 16.9 0.4 2.0 1 1 1 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KKK17865.1 - 0.0018 17.2 0.6 0.0018 17.2 0.4 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 KKK17865.1 - 0.002 18.0 0.6 0.002 18.0 0.4 1.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KKK17865.1 - 0.0044 16.1 0.2 0.0044 16.1 0.1 1.2 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.22 KKK17865.1 - 0.0048 17.2 0.2 0.0052 17.1 0.1 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.9 KKK17865.1 - 0.0059 16.0 0.2 0.0072 15.7 0.2 1.2 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Trp_halogenase PF04820.9 KKK17865.1 - 0.0081 14.8 0.4 0.0087 14.7 0.3 1.0 1 0 0 1 1 1 1 Tryptophan halogenase ThiF PF00899.16 KKK17865.1 - 0.017 14.9 0.1 0.026 14.3 0.0 1.3 1 0 0 1 1 1 0 ThiF family NAD_Gly3P_dh_N PF01210.18 KKK17865.1 - 0.033 13.9 1.3 0.038 13.7 0.9 1.4 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Pyr_redox_3 PF13738.1 KKK17865.1 - 0.13 12.3 0.3 0.14 12.2 0.2 1.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase F420_oxidored PF03807.12 KKK17865.1 - 0.24 11.8 2.0 0.33 11.4 0.2 1.8 1 1 1 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent CK_II_beta PF01214.13 KKK17869.1 - 2.2e-78 261.9 0.0 4.9e-78 260.8 0.0 1.5 1 1 0 1 1 1 1 Casein kinase II regulatory subunit Spt5_N PF11942.3 KKK17869.1 - 0.0017 18.9 7.3 0.0017 18.9 5.0 2.0 2 0 0 2 2 2 1 Spt5 transcription elongation factor, acidic N-terminal Nucleoplasmin PF03066.10 KKK17869.1 - 0.16 11.5 7.2 0.26 10.8 5.0 1.3 1 0 0 1 1 1 0 Nucleoplasmin Rubella_E2 PF05749.6 KKK17869.1 - 0.17 11.1 1.9 0.28 10.4 1.3 1.2 1 0 0 1 1 1 0 Rubella membrane glycoprotein E2 DUF3439 PF11921.3 KKK17869.1 - 1.1 8.9 6.1 1.9 8.2 4.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) CENP-B_dimeris PF09026.5 KKK17869.1 - 6.6 7.0 11.7 17 5.7 7.8 1.9 2 0 0 2 2 2 0 Centromere protein B dimerisation domain TRAM_LAG1_CLN8 PF03798.11 KKK17870.1 - 2.8e-42 144.5 23.4 2.8e-42 144.5 16.2 1.8 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.6 KKK17870.1 - 4.9e-19 67.5 0.1 9.7e-19 66.6 0.0 1.5 1 0 0 1 1 1 1 TRAM1-like protein Fungal_trans_2 PF11951.3 KKK17871.1 - 1.5e-13 50.1 0.7 2.6e-13 49.3 0.1 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Apc15p PF05841.6 KKK17871.1 - 4.6 8.0 6.6 1.3 9.7 1.8 2.1 2 0 0 2 2 2 0 Apc15p protein Rad10 PF03834.9 KKK17872.1 - 6.4e-30 102.6 0.0 1.1e-29 101.8 0.0 1.4 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH PF00633.18 KKK17872.1 - 0.00039 19.9 0.0 0.00083 18.9 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_5 PF14520.1 KKK17872.1 - 0.00043 20.3 0.0 0.00074 19.6 0.0 1.3 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH_2 PF12826.2 KKK17872.1 - 0.05 13.4 0.0 0.096 12.5 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix motif RRM_1 PF00076.17 KKK17873.1 - 8.8e-66 217.4 0.1 2e-18 65.7 0.1 5.6 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KKK17873.1 - 1.9e-46 155.9 0.0 8.3e-14 51.3 0.0 5.4 5 0 0 5 5 5 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KKK17873.1 - 1.3e-24 85.8 0.0 2.6e-08 33.5 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2857 PF11198.3 KKK17873.1 - 0.023 14.2 1.2 0.049 13.1 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2857) Nup35_RRM_2 PF14605.1 KKK17873.1 - 0.11 12.2 0.0 6.6 6.5 0.0 2.6 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif AA_permease PF00324.16 KKK17874.1 - 1.5e-103 346.7 38.7 1.8e-97 326.6 18.2 2.0 2 0 0 2 2 2 2 Amino acid permease AA_permease_2 PF13520.1 KKK17874.1 - 4.7e-19 68.2 26.5 4.7e-19 68.2 18.4 1.6 2 0 0 2 2 2 1 Amino acid permease DUF1772 PF08592.6 KKK17874.1 - 0.0096 15.6 0.8 0.0096 15.6 0.5 3.7 4 1 1 5 5 5 1 Domain of unknown function (DUF1772) Cupin_8 PF13621.1 KKK17875.1 - 3.6e-26 92.2 0.0 5.8e-26 91.5 0.0 1.3 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 KKK17875.1 - 0.0061 15.8 0.0 0.012 14.8 0.0 1.4 1 0 0 1 1 1 1 Cupin superfamily protein Cupin_2 PF07883.6 KKK17875.1 - 0.0094 15.4 0.0 0.034 13.6 0.0 1.8 2 0 0 2 2 2 1 Cupin domain Fungal_trans PF04082.13 KKK17876.1 - 1.6e-21 76.3 0.0 2.8e-21 75.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK17876.1 - 1.4e-06 28.0 14.2 2.3e-06 27.3 9.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HalX PF08663.5 KKK17876.1 - 0.13 12.2 0.1 0.27 11.2 0.1 1.4 1 0 0 1 1 1 0 HalX domain Cyt-b5 PF00173.23 KKK17877.1 - 4.2e-10 39.2 0.0 5e-10 39.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF766 PF05571.7 KKK17878.1 - 0.096 11.9 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF766) Cation_ATPase_C PF00689.16 KKK17879.1 - 6 6.3 11.3 35 3.8 7.7 1.9 1 1 1 2 2 2 0 Cation transporting ATPase, C-terminus FAD_binding_1 PF00667.15 KKK17882.1 - 6.6e-43 146.7 0.0 9.2e-43 146.2 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 KKK17882.1 - 3e-10 40.6 0.0 7.7e-10 39.3 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Glyco_hydro_31 PF01055.21 KKK17883.1 - 2.7e-154 514.2 1.4 4.3e-154 513.5 1.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Rotavirus_VP7 PF05868.6 KKK17883.1 - 0.0015 17.7 0.2 0.0027 16.9 0.1 1.3 1 0 0 1 1 1 1 Rotavirus major outer capsid protein VP7 HNH_2 PF13391.1 KKK17884.1 - 8.2e-06 25.5 0.1 2.6e-05 23.8 0.1 1.9 1 0 0 1 1 1 1 HNH endonuclease Fringe PF02434.11 KKK17885.1 - 2.7e-09 36.6 0.0 1e-08 34.7 0.0 1.8 1 1 0 1 1 1 1 Fringe-like DUF604 PF04646.7 KKK17885.1 - 9e-07 28.3 0.0 1.6e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF604 Fungal_trans PF04082.13 KKK17886.1 - 1.1e-21 76.9 0.0 2e-21 76.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK17886.1 - 5e-09 35.9 11.6 1.2e-08 34.6 8.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SRP72 PF08492.7 KKK17887.1 - 1.4e-18 66.9 1.8 1.4e-18 66.9 1.2 2.3 2 1 0 2 2 2 1 SRP72 RNA-binding domain TPR_14 PF13428.1 KKK17888.1 - 4e-09 36.3 6.1 0.075 13.7 0.1 6.7 5 2 3 8 8 8 2 Tetratricopeptide repeat TPR_19 PF14559.1 KKK17888.1 - 9.7e-06 25.8 10.5 0.15 12.4 0.1 5.4 3 3 3 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.1 KKK17888.1 - 3.5e-05 23.6 5.3 0.072 13.0 0.0 4.9 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.12 KKK17888.1 - 8.5e-05 22.1 3.4 12 6.0 0.0 5.9 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_4 PF07721.9 KKK17888.1 - 0.00029 20.9 0.0 8.6 7.1 0.0 4.9 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 KKK17888.1 - 0.0015 18.0 0.5 15 5.3 0.0 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat Apc3 PF12895.2 KKK17888.1 - 0.0017 18.4 7.3 5.7 7.1 0.1 4.3 2 1 2 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_20 PF14561.1 KKK17888.1 - 0.011 15.7 1.3 0.11 12.5 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat SPO22 PF08631.5 KKK17888.1 - 0.012 14.6 1.0 0.048 12.7 0.1 2.2 2 0 0 2 2 2 0 Meiosis protein SPO22/ZIP4 like TPR_16 PF13432.1 KKK17888.1 - 0.014 16.0 2.4 15 6.4 0.0 4.6 4 1 1 5 5 5 0 Tetratricopeptide repeat BTAD PF03704.12 KKK17888.1 - 0.026 14.8 0.4 0.026 14.8 0.3 3.7 3 1 1 4 4 4 0 Bacterial transcriptional activator domain PPR PF01535.15 KKK17888.1 - 0.033 14.1 2.1 33 4.7 0.0 4.8 6 0 0 6 6 6 0 PPR repeat TPR_6 PF13174.1 KKK17888.1 - 0.035 14.5 0.9 1.4e+02 3.2 0.0 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat YfdX PF10938.3 KKK17888.1 - 0.07 12.7 1.5 0.98 9.0 0.1 3.1 3 1 0 3 3 3 0 YfdX protein vWA-TerF-like PF10138.4 KKK17889.1 - 0.00016 21.6 0.0 0.00022 21.1 0.0 1.2 1 0 0 1 1 1 1 vWA found in TerF C terminus GFO_IDH_MocA PF01408.17 KKK17890.1 - 2.1e-11 44.3 0.0 5.5e-11 43.0 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Ribosomal_L3 PF00297.17 KKK17938.1 - 1.5e-118 394.9 9.2 2.1e-118 394.4 6.4 1.2 1 0 0 1 1 1 1 Ribosomal protein L3 TPR_1 PF00515.23 KKK17938.1 - 9.5e-51 167.4 21.9 6.3e-08 31.8 0.0 10.8 11 1 0 11 11 11 9 Tetratricopeptide repeat TPR_2 PF07719.12 KKK17938.1 - 6.7e-44 144.2 16.7 2e-05 24.1 0.0 10.7 11 0 0 11 11 10 9 Tetratricopeptide repeat TPR_11 PF13414.1 KKK17938.1 - 2.2e-42 142.5 19.2 2.7e-10 39.7 0.3 6.4 3 2 1 6 6 6 6 TPR repeat TPR_8 PF13181.1 KKK17938.1 - 2e-37 124.1 16.5 4e-05 23.0 0.6 10.4 8 1 2 10 10 10 9 Tetratricopeptide repeat TPR_12 PF13424.1 KKK17938.1 - 1.3e-28 98.6 20.2 6.7e-07 29.1 0.2 7.3 3 2 5 8 8 8 7 Tetratricopeptide repeat TPR_16 PF13432.1 KKK17938.1 - 1.2e-26 92.6 16.3 2.5e-06 28.0 0.0 6.8 4 2 3 8 8 7 6 Tetratricopeptide repeat TPR_17 PF13431.1 KKK17938.1 - 9.2e-25 84.7 12.9 0.0019 18.2 0.1 9.9 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_14 PF13428.1 KKK17938.1 - 1.1e-23 81.5 17.0 0.00012 22.4 0.0 9.9 4 2 7 11 11 11 8 Tetratricopeptide repeat TPR_7 PF13176.1 KKK17938.1 - 9.5e-22 75.0 9.8 0.0048 16.5 0.0 9.7 9 1 0 9 9 9 5 Tetratricopeptide repeat TPR_19 PF14559.1 KKK17938.1 - 7.7e-21 74.2 10.7 0.00012 22.3 0.0 6.9 5 2 0 6 6 6 4 Tetratricopeptide repeat TPR_6 PF13174.1 KKK17938.1 - 1.9e-18 65.5 15.9 0.0062 16.9 0.0 10.2 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_9 PF13371.1 KKK17938.1 - 3.8e-14 52.2 8.1 0.00065 19.4 0.0 6.5 2 1 4 7 7 7 5 Tetratricopeptide repeat Apc3 PF12895.2 KKK17938.1 - 8.3e-13 48.2 8.5 5.7e-08 32.7 2.1 4.0 3 1 1 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.1 KKK17938.1 - 9.1e-06 24.9 15.8 0.0078 15.3 2.5 5.1 2 1 3 5 5 5 3 Tetratricopeptide repeat TPR_21 PF09976.4 KKK17938.1 - 0.0008 19.3 7.3 0.38 10.6 2.2 4.3 2 2 2 4 4 4 2 Tetratricopeptide repeat TPR_20 PF14561.1 KKK17938.1 - 0.0072 16.4 0.1 0.99 9.5 0.0 3.6 2 1 1 3 3 3 1 Tetratricopeptide repeat BTAD PF03704.12 KKK17938.1 - 0.064 13.5 5.9 3.2 8.0 0.1 3.6 3 0 0 3 3 3 0 Bacterial transcriptional activator domain TPR_10 PF13374.1 KKK17938.1 - 0.14 12.1 10.4 28 4.8 0.1 6.0 5 0 0 5 5 5 0 Tetratricopeptide repeat MIT PF04212.13 KKK17938.1 - 0.58 10.0 16.5 3.2 7.6 1.1 5.5 5 1 0 5 5 5 0 MIT (microtubule interacting and transport) domain NuiA PF07924.6 KKK17940.1 - 0.28 11.0 1.6 4.8 7.0 1.1 2.2 1 1 0 1 1 1 0 Nuclease A inhibitor-like protein Nol1_Nop2_Fmu PF01189.12 KKK17958.1 - 9.8e-83 277.7 0.0 3.1e-82 276.1 0.0 1.8 1 1 0 1 1 1 1 NOL1/NOP2/sun family FtsJ PF01728.14 KKK17958.1 - 5.5e-05 23.2 0.0 0.0001 22.3 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_31 PF13847.1 KKK17958.1 - 0.011 15.2 0.0 0.023 14.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain DDE_Tnp_1_6 PF13751.1 KKK17958.1 - 0.39 10.7 5.1 1.1 9.2 3.6 1.7 1 0 0 1 1 1 0 Transposase DDE domain G0-G1_switch_2 PF15103.1 KKK17958.1 - 1.2 9.3 0.0 1.2 9.3 0.0 4.0 3 1 1 4 4 4 0 G0/G1 switch protein 2 vMSA PF00695.14 KKK17958.1 - 9 5.3 9.4 15 4.6 6.5 1.2 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus MORN PF02493.15 KKK17959.1 - 1.6e-13 49.4 25.0 3.3e-05 23.3 0.3 4.6 4 0 0 4 4 4 4 MORN repeat zf-C3HC4_3 PF13920.1 KKK17959.1 - 6.8e-12 44.8 9.7 1.2e-11 44.1 6.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) UCH PF00443.24 KKK17959.1 - 7.8e-10 38.3 0.0 2.2e-09 36.8 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase USP7_ICP0_bdg PF12436.3 KKK17959.1 - 0.0009 18.5 0.0 0.0009 18.5 0.0 1.8 2 0 0 2 2 2 1 ICP0-binding domain of Ubiquitin-specific protease 7 zf-C3HC4_2 PF13923.1 KKK17959.1 - 0.015 15.3 11.7 0.032 14.2 8.1 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Borrelia_P83 PF05262.6 KKK17959.1 - 0.02 13.1 1.8 0.032 12.5 1.2 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF605 PF04652.11 KKK17959.1 - 0.094 12.0 40.8 0.21 10.9 9.8 2.4 2 0 0 2 2 2 0 Vta1 like DS PF01916.12 KKK17960.1 - 2e-140 467.1 0.0 2.2e-140 466.9 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase CmcH_NodU PF02543.10 KKK17960.1 - 0.064 12.3 0.1 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 Carbamoyltransferase Lentiviral_Tat PF02998.9 KKK17968.1 - 0.013 15.2 0.2 0.081 12.7 0.1 2.2 2 0 0 2 2 2 0 Lentiviral Tat protein MutS_V PF00488.16 KKK17969.1 - 1.4e-94 315.8 0.0 2.2e-94 315.2 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 KKK17969.1 - 3.5e-40 137.9 1.9 7e-40 137.0 1.3 1.5 1 0 0 1 1 1 1 MutS domain III MutS_II PF05188.12 KKK17969.1 - 3.3e-20 72.5 0.4 2.9e-19 69.4 0.0 2.7 3 0 0 3 3 3 1 MutS domain II MutS_IV PF05190.13 KKK17969.1 - 3.8e-16 59.0 0.9 3.8e-16 59.0 0.6 2.0 2 0 0 2 2 2 1 MutS family domain IV MutS_I PF01624.15 KKK17969.1 - 4e-14 52.6 0.0 2.3e-13 50.1 0.0 2.2 2 0 0 2 2 2 1 MutS domain I Gpi1 PF05024.10 KKK17970.1 - 8e-62 208.2 8.7 8e-62 208.2 6.1 2.0 2 0 0 2 2 2 1 N-acetylglucosaminyl transferase component (Gpi1) Proteasome PF00227.21 KKK17975.1 - 1.6e-56 190.6 0.0 4.4e-32 110.9 0.0 2.2 1 1 1 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.4 KKK17975.1 - 1.8e-11 43.1 0.3 4.1e-11 41.9 0.0 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Amidohydro_2 PF04909.9 KKK17976.1 - 5.4e-44 150.7 0.2 6.5e-44 150.5 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase RINGv PF12906.2 KKK17977.1 - 1.5e-09 37.7 3.8 3.4e-09 36.6 0.6 2.3 2 0 0 2 2 2 1 RING-variant domain zf-RING_2 PF13639.1 KKK17977.1 - 0.011 15.5 3.8 0.028 14.2 0.8 2.2 2 0 0 2 2 2 0 Ring finger domain DUF1206 PF06724.6 KKK17977.1 - 0.062 13.0 0.5 0.062 13.0 0.3 2.0 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1206) PgaD PF13994.1 KKK17977.1 - 1.7 8.1 6.8 0.32 10.4 0.8 2.0 2 0 0 2 2 2 0 PgaD-like protein RRM_6 PF14259.1 KKK17978.1 - 9.9e-20 70.3 0.0 8.5e-12 44.8 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KKK17978.1 - 1.7e-19 69.1 0.2 2.7e-13 49.3 0.0 3.3 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KKK17978.1 - 3.2e-10 39.7 0.0 0.00083 19.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 KKK17978.1 - 0.0057 16.3 0.0 1.7 8.4 0.0 3.3 3 0 0 3 3 3 1 Limkain b1 Laminin_G_2 PF02210.19 KKK17978.1 - 0.13 12.3 0.0 1.4 9.0 0.0 2.2 2 0 0 2 2 2 0 Laminin G domain TC1 PF15063.1 KKK17978.1 - 0.21 11.1 1.5 9.9 5.7 0.0 2.9 2 1 0 2 2 2 0 Thyroid cancer protein 1 Sugar_tr PF00083.19 KKK17979.1 - 1.8e-81 274.0 30.2 2.3e-81 273.7 21.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KKK17979.1 - 6.3e-11 41.5 45.1 9.6e-10 37.6 11.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3824 PF12868.2 KKK17993.1 - 1.2e-35 123.4 33.3 1.2e-35 123.4 23.1 7.2 5 1 3 8 8 8 3 Domain of unknwon function (DUF3824) Vac7 PF12751.2 KKK17994.1 - 5.6e-215 713.4 1.7 5.6e-215 713.4 1.2 1.8 2 0 0 2 2 2 1 Vacuolar segregation subunit 7 Pkinase PF00069.20 KKK18005.1 - 4.3e-24 85.0 0.0 1.2e-23 83.5 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK18005.1 - 4.6e-08 32.4 0.0 0.0074 15.3 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 KKK18005.1 - 0.014 15.1 0.2 0.048 13.3 0.1 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family Ras PF00071.17 KKK18006.1 - 6.2e-57 191.5 0.0 7.4e-57 191.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KKK18006.1 - 1.5e-20 73.8 0.0 2.2e-20 73.3 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KKK18006.1 - 1e-14 54.1 0.0 1.7e-14 53.4 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KKK18006.1 - 2.4e-06 26.8 0.0 3e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 KKK18006.1 - 1.2e-05 24.8 0.0 2.9e-05 23.6 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KKK18006.1 - 0.00017 21.5 0.0 0.00027 20.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 KKK18006.1 - 0.0097 15.9 0.0 0.014 15.3 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KKK18006.1 - 0.091 12.9 0.0 0.25 11.4 0.0 1.7 1 1 0 1 1 1 0 AAA domain CorA PF01544.13 KKK18009.1 - 8.3e-11 41.4 0.2 1.6e-10 40.5 0.1 1.5 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Metallophos PF00149.23 KKK18010.1 - 1.8e-13 50.3 0.1 3.2e-13 49.5 0.1 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KKK18010.1 - 2e-07 30.9 0.2 3.2e-07 30.2 0.1 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.1 KKK18010.1 - 0.15 11.2 0.0 0.25 10.4 0.0 1.3 1 0 0 1 1 1 0 Metallophosphoesterase, calcineurin superfamily LCCL PF03815.14 KKK18011.1 - 5.3e-22 77.6 0.0 8.9e-22 76.8 0.0 1.3 1 0 0 1 1 1 1 LCCL domain Gly_transf_sug PF04488.10 KKK18012.1 - 5.5e-12 45.9 0.0 1.5e-11 44.6 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif CUB PF00431.15 KKK18012.1 - 0.098 12.7 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 CUB domain ThiF PF00899.16 KKK18013.1 - 2.6e-35 121.1 0.0 4.3e-35 120.4 0.0 1.4 1 0 0 1 1 1 1 ThiF family TrkA_N PF02254.13 KKK18013.1 - 0.033 14.1 0.3 0.075 13.0 0.0 1.7 2 0 0 2 2 2 0 TrkA-N domain Glyco_hydro_17 PF00332.13 KKK18013.1 - 0.047 12.7 0.0 0.074 12.0 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 17 ApbA PF02558.11 KKK18013.1 - 0.11 11.8 0.1 0.2 11.0 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DUF4336 PF14234.1 KKK18014.1 - 1.7e-16 60.2 0.0 1.9e-12 46.9 0.0 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4336) Nse4_C PF08743.5 KKK18015.1 - 1.1e-35 121.5 0.0 2.5e-35 120.3 0.0 1.7 1 0 0 1 1 1 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.1 KKK18015.1 - 2.8e-19 68.6 0.0 9.1e-19 67.0 0.0 1.9 1 0 0 1 1 1 1 Binding domain of Nse4/EID3 to Nse3-MAGE Cupin_8 PF13621.1 KKK18015.1 - 0.013 14.9 0.3 0.023 14.2 0.2 1.3 1 0 0 1 1 1 0 Cupin-like domain Peptidase_S64 PF08192.6 KKK18015.1 - 1 7.6 5.2 0.29 9.4 1.6 1.5 2 0 0 2 2 2 0 Peptidase family S64 MARVEL PF01284.18 KKK18016.1 - 3.6e-21 75.4 14.6 4.6e-21 75.1 10.2 1.1 1 0 0 1 1 1 1 Membrane-associating domain DUF2976 PF11190.3 KKK18016.1 - 5.8 6.5 6.8 0.89 9.1 1.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2976) GMC_oxred_N PF00732.14 KKK18017.1 - 8.8e-30 103.8 0.0 1.6e-29 102.9 0.0 1.5 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KKK18017.1 - 4e-16 59.5 0.5 6.7e-16 58.8 0.3 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 KKK18017.1 - 2e-10 40.1 2.7 2.1e-05 23.6 0.0 2.5 2 1 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KKK18017.1 - 1.5e-06 27.3 0.1 0.016 14.0 0.0 2.4 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 KKK18017.1 - 3.7e-06 26.8 0.4 2.2e-05 24.3 0.0 2.6 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KKK18017.1 - 7.6e-06 25.9 0.0 0.015 15.2 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KKK18017.1 - 9.1e-06 24.3 0.1 4.9e-05 21.9 0.0 1.9 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.1 KKK18017.1 - 2.4e-05 24.4 0.0 0.27 11.2 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KKK18017.1 - 0.0006 20.1 0.4 0.17 12.3 0.0 3.4 4 0 0 4 4 3 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KKK18017.1 - 0.0023 17.0 0.1 0.0051 15.9 0.0 1.6 2 0 0 2 2 2 1 Thi4 family FAD_oxidored PF12831.2 KKK18017.1 - 0.0023 17.0 0.0 0.028 13.5 0.0 2.4 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 KKK18017.1 - 0.0061 15.6 0.1 0.011 14.8 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 KKK18017.1 - 0.01 14.8 0.0 0.016 14.1 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_binding_9 PF13454.1 KKK18017.1 - 0.026 14.2 0.1 0.085 12.6 0.0 2.0 2 0 0 2 2 2 0 FAD-NAD(P)-binding Trp_halogenase PF04820.9 KKK18017.1 - 0.071 11.7 0.1 0.1 11.1 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase MMR_HSR1 PF01926.18 KKK18018.1 - 1.2e-14 54.2 0.0 1.6e-13 50.5 0.0 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase DUF258 PF03193.11 KKK18018.1 - 5.1e-06 25.7 0.1 9.2e-06 24.9 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function, DUF258 FeoB_N PF02421.13 KKK18018.1 - 2e-05 23.9 0.1 3.3e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B MobB PF03205.9 KKK18018.1 - 0.00086 19.0 0.1 0.0017 18.0 0.1 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AIG1 PF04548.11 KKK18018.1 - 0.00093 18.3 0.0 0.0015 17.6 0.0 1.3 1 0 0 1 1 1 1 AIG1 family Septin PF00735.13 KKK18018.1 - 0.0011 18.0 0.0 0.0019 17.2 0.0 1.2 1 0 0 1 1 1 1 Septin PduV-EutP PF10662.4 KKK18018.1 - 0.0019 17.7 0.6 0.38 10.2 0.0 3.4 3 1 0 3 3 3 1 Ethanolamine utilisation - propanediol utilisation AAA_18 PF13238.1 KKK18018.1 - 0.0059 16.9 0.0 0.015 15.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain GTP_EFTU PF00009.22 KKK18018.1 - 0.0088 15.4 0.0 0.12 11.7 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Miro PF08477.8 KKK18018.1 - 0.01 16.3 0.1 0.099 13.1 0.0 2.2 2 0 0 2 2 2 0 Miro-like protein Dynamin_N PF00350.18 KKK18018.1 - 0.011 15.5 0.1 0.19 11.5 0.0 2.5 1 1 1 2 2 2 0 Dynamin family AAA_17 PF13207.1 KKK18018.1 - 0.015 16.1 0.1 0.048 14.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 KKK18018.1 - 0.017 15.0 0.0 0.061 13.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain ArgK PF03308.11 KKK18018.1 - 0.023 13.4 0.0 0.039 12.7 0.0 1.4 1 0 0 1 1 1 0 ArgK protein Arf PF00025.16 KKK18018.1 - 0.05 12.8 0.0 0.54 9.4 0.0 2.1 2 0 0 2 2 2 0 ADP-ribosylation factor family DUF2570 PF10828.3 KKK18018.1 - 0.1 12.2 0.4 0.35 10.4 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2570) PI3Ka PF00613.15 KKK18019.1 - 6.5e-60 201.4 0.1 1.1e-59 200.7 0.1 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.22 KKK18019.1 - 4.7e-42 144.0 0.0 1.8e-40 138.9 0.0 2.6 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.19 KKK18019.1 - 2.3e-27 95.4 0.0 3.9e-27 94.7 0.0 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 Histidinol_dh PF00815.15 KKK18021.1 - 1e-175 584.3 6.2 1.6e-175 583.6 4.3 1.3 1 0 0 1 1 1 1 Histidinol dehydrogenase PRA-CH PF01502.13 KKK18021.1 - 3.1e-24 84.4 0.0 7.7e-24 83.1 0.0 1.7 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.12 KKK18021.1 - 4.2e-12 46.1 0.3 1.6e-11 44.2 0.2 2.1 1 0 0 1 1 1 1 Phosphoribosyl-ATP pyrophosphohydrolase MazG PF03819.12 KKK18021.1 - 0.0056 16.6 0.2 0.014 15.3 0.2 1.7 1 0 0 1 1 1 1 MazG nucleotide pyrophosphohydrolase domain Utp11 PF03998.8 KKK18022.1 - 1.2e-54 185.7 30.0 1.6e-54 185.3 20.8 1.2 1 0 0 1 1 1 1 Utp11 protein DUF3523 PF12037.3 KKK18022.1 - 0.00013 21.0 9.0 0.00013 21.0 6.2 2.5 2 1 0 2 2 2 1 Domain of unknown function (DUF3523) Sigma70_ner PF04546.8 KKK18022.1 - 0.051 13.1 31.8 0.72 9.4 5.7 2.4 1 1 1 2 2 2 0 Sigma-70, non-essential region Glyco_hydro_47 PF01532.15 KKK18024.1 - 4e-137 457.5 0.0 4.5e-137 457.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 TipAS PF07739.8 KKK18024.1 - 0.095 13.0 0.1 0.22 11.8 0.0 1.6 1 0 0 1 1 1 0 TipAS antibiotic-recognition domain Fungal_trans PF04082.13 KKK18025.1 - 6e-15 54.8 0.7 2.2e-14 52.9 0.0 2.1 2 1 0 2 2 2 1 Fungal specific transcription factor domain Ferric_reduct PF01794.14 KKK18026.1 - 1.2e-20 73.8 9.6 1.2e-20 73.8 6.7 1.9 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 KKK18026.1 - 1.1e-14 54.1 0.1 6.3e-09 35.6 0.0 2.5 2 0 0 2 2 2 2 FAD-binding domain NAD_binding_6 PF08030.7 KKK18026.1 - 1.2e-11 44.7 0.1 1.6e-09 37.8 0.0 2.7 2 1 1 3 3 3 2 Ferric reductase NAD binding domain NAD_binding_1 PF00175.16 KKK18026.1 - 0.036 14.6 0.0 0.14 12.7 0.0 2.1 2 1 0 2 2 2 0 Oxidoreductase NAD-binding domain ABC2_membrane PF01061.19 KKK18027.1 - 8.5e-94 312.5 59.3 9.7e-49 165.3 14.7 3.1 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.22 KKK18027.1 - 1.2e-37 129.2 0.0 4e-18 66.0 0.0 2.6 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 KKK18027.1 - 6.9e-37 125.2 5.8 1.3e-33 114.7 0.0 3.3 3 0 0 3 3 3 2 CDR ABC transporter ABC_trans_N PF14510.1 KKK18027.1 - 1.4e-23 82.7 0.0 1.8e-22 79.1 0.1 2.4 2 0 0 2 2 2 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 KKK18027.1 - 5e-07 29.3 0.1 0.00031 20.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 KKK18027.1 - 2.1e-06 27.0 0.0 0.00017 20.7 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 KKK18027.1 - 0.00037 20.5 1.1 0.0046 16.9 0.1 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.1 KKK18027.1 - 0.00086 19.2 1.5 0.053 13.4 0.0 2.8 3 0 0 3 3 2 1 AAA domain AAA_29 PF13555.1 KKK18027.1 - 0.00091 18.7 1.8 0.02 14.3 0.2 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.1 KKK18027.1 - 0.0022 18.1 0.1 1 9.5 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KKK18027.1 - 0.0029 18.4 0.0 0.61 10.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain cobW PF02492.14 KKK18027.1 - 0.0039 16.6 1.7 0.017 14.5 0.0 2.4 3 0 0 3 3 2 1 CobW/HypB/UreG, nucleotide-binding domain SMC_N PF02463.14 KKK18027.1 - 0.0064 15.7 0.0 0.42 9.8 0.0 3.1 3 1 0 4 4 4 1 RecF/RecN/SMC N terminal domain AAA_18 PF13238.1 KKK18027.1 - 0.0075 16.5 0.0 0.7 10.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.1 KKK18027.1 - 0.017 15.1 0.1 2.4 8.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain Miro PF08477.8 KKK18027.1 - 0.022 15.2 0.0 5.5 7.5 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein RNA_helicase PF00910.17 KKK18027.1 - 0.038 14.1 0.0 12 6.0 0.0 2.7 2 0 0 2 2 2 0 RNA helicase FtsK_SpoIIIE PF01580.13 KKK18027.1 - 0.064 12.7 0.3 0.58 9.6 0.1 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family UPF0079 PF02367.12 KKK18027.1 - 0.071 12.7 0.8 10 5.7 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 ABC2_membrane_3 PF12698.2 KKK18027.1 - 0.094 11.7 50.6 0.026 13.5 12.9 3.0 2 1 0 2 2 2 0 ABC-2 family transporter protein AAA_28 PF13521.1 KKK18027.1 - 0.11 12.4 0.1 0.83 9.5 0.1 2.4 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 KKK18027.1 - 0.12 11.7 3.0 21 4.4 0.0 3.5 2 1 1 3 3 3 0 AAA-like domain NACHT PF05729.7 KKK18027.1 - 0.18 11.4 5.5 3.2 7.3 0.2 3.6 4 0 0 4 4 4 0 NACHT domain bZIP_1 PF00170.16 KKK18028.1 - 3.9e-05 23.5 11.9 5.2e-05 23.1 8.3 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KKK18028.1 - 7e-05 22.5 12.5 0.00012 21.8 8.7 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 KKK18028.1 - 0.0016 18.6 9.3 0.0023 18.2 6.4 1.2 1 0 0 1 1 1 1 bZIP Maf transcription factor NinG PF05766.7 KKK18028.1 - 0.072 12.8 1.6 0.092 12.4 1.1 1.2 1 0 0 1 1 1 0 Bacteriophage Lambda NinG protein DivIC PF04977.10 KKK18028.1 - 0.39 10.2 5.1 0.14 11.6 1.3 1.9 1 1 1 2 2 2 0 Septum formation initiator Pkinase PF00069.20 KKK18029.1 - 1.7e-06 27.4 0.0 2.5e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain UBX PF00789.15 KKK18030.1 - 1.5e-09 37.7 0.0 3e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.1 KKK18030.1 - 2.6e-09 36.4 0.0 6.4e-09 35.2 0.0 1.7 1 0 0 1 1 1 1 UBA-like domain DUF4337 PF14235.1 KKK18030.1 - 4.5 7.0 9.1 9.3 6.0 6.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) LSM PF01423.17 KKK18031.1 - 5.5e-20 70.6 0.2 7.3e-20 70.2 0.2 1.2 1 0 0 1 1 1 1 LSM domain FoP_duplication PF13865.1 KKK18031.1 - 0.5 10.8 8.9 1.1 9.7 6.2 1.6 1 1 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Dioxygenase_C PF00775.16 KKK18033.1 - 1e-42 145.4 0.1 1.3e-39 135.3 0.0 2.2 2 0 0 2 2 2 2 Dioxygenase Dioxygenase_N PF04444.9 KKK18033.1 - 1.3e-18 66.7 0.0 2.4e-18 65.8 0.0 1.5 1 0 0 1 1 1 1 Catechol dioxygenase N terminus Med15 PF09606.5 KKK18034.1 - 0.00044 18.6 52.0 0.0007 17.9 36.0 1.4 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal Zn_clus PF00172.13 KKK18034.1 - 0.039 13.8 9.7 0.091 12.6 6.8 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain SPX PF03105.14 KKK18034.1 - 0.22 11.2 22.2 0.029 14.1 8.3 2.5 2 0 0 2 2 2 0 SPX domain zf-DHHC PF01529.15 KKK18034.1 - 3.9 6.8 7.2 0.14 11.5 0.7 1.9 2 0 0 2 2 2 0 DHHC palmitoyltransferase Kei1 PF08552.6 KKK18034.1 - 8.2 6.0 5.7 17 4.9 3.9 1.6 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 CYSTM PF12734.2 KKK18035.1 - 6.4e-10 38.9 12.5 6.4e-10 38.9 8.7 5.3 1 1 1 2 2 2 1 Cysteine-rich TM module stress tolerance Peptidase_M16 PF00675.15 KKK18036.1 - 2.8e-57 192.6 0.1 1.4e-56 190.4 0.2 2.1 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 KKK18036.1 - 7e-42 143.1 0.0 5.6e-40 136.9 0.0 2.3 2 0 0 2 2 2 1 Peptidase M16 inactive domain Epimerase PF01370.16 KKK18036.1 - 8.7e-22 77.7 0.0 1.6e-21 76.8 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KKK18036.1 - 2.8e-10 39.3 0.0 4.2e-10 38.7 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 KKK18036.1 - 9.7e-08 32.2 0.0 5.4e-07 29.7 0.0 2.1 2 0 0 2 2 2 1 NADH(P)-binding adh_short PF00106.20 KKK18036.1 - 1.2e-06 28.5 0.6 4.7e-06 26.6 0.1 2.2 3 0 0 3 3 3 1 short chain dehydrogenase RmlD_sub_bind PF04321.12 KKK18036.1 - 0.00011 21.2 0.0 0.00021 20.2 0.0 1.5 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 KKK18036.1 - 0.0006 18.8 0.0 0.014 14.3 0.0 2.3 1 1 0 1 1 1 1 Male sterility protein Semialdhyde_dh PF01118.19 KKK18036.1 - 0.018 15.3 0.0 0.099 12.9 0.0 2.3 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Ldh_1_N PF00056.18 KKK18036.1 - 0.025 14.3 0.1 0.11 12.3 0.0 2.1 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain Saccharop_dh PF03435.13 KKK18036.1 - 0.029 13.3 0.0 0.047 12.6 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase KR PF08659.5 KKK18036.1 - 0.037 13.6 0.0 0.12 12.0 0.0 1.8 2 0 0 2 2 2 0 KR domain PLAC8 PF04749.12 KKK18037.1 - 5e-25 88.1 9.0 5.8e-25 87.9 6.2 1.0 1 0 0 1 1 1 1 PLAC8 family Nol1_Nop2_Fmu PF01189.12 KKK18038.1 - 4.7e-29 101.6 0.0 2.8e-16 59.7 0.0 4.2 2 1 2 4 4 4 4 NOL1/NOP2/sun family Methyltransf_26 PF13659.1 KKK18038.1 - 0.0086 16.0 0.0 0.017 15.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain DUF1509 PF07420.6 KKK18039.1 - 1.1 8.5 17.6 0.6 9.3 10.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1509) PRP38_assoc PF12871.2 KKK18039.1 - 2 9.0 19.1 4 8.0 13.2 1.5 1 1 0 1 1 1 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Corona_nucleoca PF00937.13 KKK18039.1 - 3.5 6.4 8.4 5 5.9 5.8 1.1 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Vps39_2 PF10367.4 KKK18040.1 - 0.0013 18.8 0.0 0.0046 17.1 0.0 1.9 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.4 KKK18040.1 - 0.0091 16.0 0.3 0.11 12.5 0.1 2.6 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 CASP_C PF08172.7 KKK18041.1 - 1.6e-90 302.4 4.4 1.6e-90 302.4 3.0 3.7 3 1 1 4 4 4 1 CASP C terminal MotB_plug PF13677.1 KKK18041.1 - 0.04 13.2 0.5 0.12 11.7 0.4 1.8 1 0 0 1 1 1 0 Membrane MotB of proton-channel complex MotA/MotB UPF0184 PF03670.8 KKK18041.1 - 0.37 10.9 11.9 0.99 9.6 0.3 4.2 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0184) DUF3584 PF12128.3 KKK18041.1 - 2.5 5.3 46.8 0.013 12.8 16.9 3.8 3 1 1 4 4 4 0 Protein of unknown function (DUF3584) Tropomyosin_1 PF12718.2 KKK18041.1 - 9.9 6.0 65.4 3.2 7.5 5.8 5.3 3 1 2 5 5 5 0 Tropomyosin like DUF3455 PF11937.3 KKK18042.1 - 1.4e-49 168.4 0.1 1.7e-49 168.1 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) DUF2990 PF11693.3 KKK18042.1 - 1.8e-26 91.7 2.3 4.3e-26 90.5 1.6 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2990) Fibrillarin PF01269.12 KKK18043.1 - 9.9e-107 355.0 0.0 1.2e-106 354.8 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.5 KKK18043.1 - 2.9e-06 26.9 0.1 5.4e-06 26.0 0.0 1.3 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.14 KKK18043.1 - 0.045 13.2 0.1 0.059 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.1 KKK18043.1 - 0.13 11.8 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain 2-Hacid_dh_C PF02826.14 KKK18044.1 - 3.7e-55 185.8 0.0 5.7e-55 185.2 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Ribosomal_L22 PF00237.14 KKK18044.1 - 7.1e-35 119.1 0.0 1.5e-34 118.0 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e 2-Hacid_dh PF00389.25 KKK18044.1 - 1.5e-18 66.5 0.0 2.7e-18 65.6 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 KKK18044.1 - 0.00096 19.0 0.3 0.0051 16.6 0.1 2.1 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase ADH_N PF08240.7 KKK18045.1 - 2.6e-28 97.9 0.1 4e-28 97.3 0.1 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Chitin_bind_3 PF03067.10 KKK18046.1 - 7.6e-12 45.8 1.6 7.6e-12 45.8 1.1 3.0 2 1 0 2 2 2 1 Chitin binding domain DUF966 PF06136.8 KKK18046.1 - 6.3 6.1 14.1 8.5 5.6 9.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) GAT PF03127.9 KKK18047.1 - 2.3e-14 53.2 1.5 4.8e-14 52.1 0.1 2.2 3 0 0 3 3 3 1 GAT domain Sirohm_synth_M PF14824.1 KKK18047.1 - 0.097 11.6 0.1 0.24 10.4 0.1 1.7 1 0 0 1 1 1 0 Sirohaem biosynthesis protein central Aminotran_1_2 PF00155.16 KKK18048.1 - 4.3e-17 62.1 0.0 5.1e-17 61.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II CAP18_C PF12153.3 KKK18048.1 - 0.11 12.2 0.5 0.24 11.0 0.3 1.5 1 0 0 1 1 1 0 LPS binding domain of CAP18 (C terminal) Pectate_lyase_3 PF12708.2 KKK18049.1 - 6e-88 294.7 15.3 1.3e-70 238.0 8.5 2.5 2 0 0 2 2 2 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 KKK18049.1 - 4.8e-06 25.9 1.6 0.041 13.3 0.2 3.0 3 0 0 3 3 3 2 N terminal extension of bacteriophage endosialidase NosD PF05048.8 KKK18049.1 - 0.00014 21.1 2.7 0.00037 19.7 1.9 1.7 1 0 0 1 1 1 1 Periplasmic copper-binding protein (NosD) Ank_2 PF12796.2 KKK18050.1 - 2.3e-50 168.8 6.4 1.2e-16 60.7 0.4 4.5 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 KKK18050.1 - 3.2e-48 159.2 15.2 1.9e-09 36.8 0.2 9.7 9 1 0 9 9 9 7 Ankyrin repeat Ank_4 PF13637.1 KKK18050.1 - 4e-39 132.3 9.4 1.4e-11 44.5 0.3 7.1 5 2 2 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 KKK18050.1 - 7.9e-34 112.3 8.3 0.00015 21.6 0.1 9.3 9 0 0 9 9 9 7 Ankyrin repeat Ank_5 PF13857.1 KKK18050.1 - 3.1e-33 113.0 16.8 4.2e-08 33.1 0.2 7.6 5 2 2 7 7 7 6 Ankyrin repeats (many copies) CorA PF01544.13 KKK18050.1 - 4.6e-10 39.0 1.6 1.4e-09 37.3 0.9 1.8 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein PRP1_N PF06424.7 KKK18050.1 - 0.024 14.9 0.8 0.058 13.7 0.6 1.6 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal GLE1 PF07817.8 KKK18050.1 - 0.033 13.1 0.6 0.058 12.3 0.4 1.3 1 0 0 1 1 1 0 GLE1-like protein adh_short PF00106.20 KKK18052.1 - 8.4e-30 103.8 0.4 1e-29 103.5 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KKK18052.1 - 6.4e-18 65.4 0.2 7.9e-18 65.1 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KKK18052.1 - 1.5e-13 50.8 0.2 2.2e-13 50.2 0.2 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KKK18052.1 - 4.6e-07 29.5 0.2 6.4e-07 29.0 0.1 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family ACT_7 PF13840.1 KKK18052.1 - 0.0058 16.1 0.4 0.14 11.6 0.0 2.5 2 0 0 2 2 2 1 ACT domain Polysacc_synt_2 PF02719.10 KKK18052.1 - 0.007 15.2 0.0 0.0094 14.8 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 KKK18052.1 - 0.013 15.4 2.0 0.14 12.1 1.4 2.5 1 1 0 1 1 1 0 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 KKK18052.1 - 0.025 14.3 0.2 0.065 13.0 0.1 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase RmlD_sub_bind PF04321.12 KKK18052.1 - 0.086 11.7 0.2 0.17 10.7 0.1 1.5 1 1 0 1 1 1 0 RmlD substrate binding domain Trp_syntA PF00290.15 KKK18052.1 - 0.099 11.1 0.0 0.16 10.4 0.0 1.3 1 0 0 1 1 1 0 Tryptophan synthase alpha chain Fungal_trans PF04082.13 KKK18053.1 - 2.8e-14 52.6 0.0 1.3e-13 50.4 0.0 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK18053.1 - 1.6e-06 27.9 7.0 2.9e-06 27.0 4.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mito_carr PF00153.22 KKK18081.1 - 4.9e-27 93.4 0.1 6.2e-26 89.9 0.0 2.0 2 0 0 2 2 2 1 Mitochondrial carrier protein Peptidase_C50 PF03568.12 KKK18082.1 - 2.8e-131 437.7 0.0 5.6e-131 436.7 0.0 1.5 1 0 0 1 1 1 1 Peptidase family C50 CHAT PF12770.2 KKK18082.1 - 0.00013 21.1 4.2 0.00038 19.6 0.0 3.3 5 0 0 5 5 5 1 CHAT domain TPR_12 PF13424.1 KKK18082.1 - 0.0012 18.7 18.6 0.034 14.0 0.1 6.3 5 2 1 7 7 7 2 Tetratricopeptide repeat TPR_11 PF13414.1 KKK18082.1 - 0.1 12.2 4.1 15 5.3 0.0 4.6 3 1 1 4 4 4 0 TPR repeat DUF1980 PF09323.5 KKK18082.1 - 0.15 11.8 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) TPR_1 PF00515.23 KKK18082.1 - 0.39 10.4 2.5 17 5.2 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.12 KKK18082.1 - 0.64 10.0 15.3 2.1 8.4 0.0 5.6 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_10 PF13374.1 KKK18082.1 - 5.7 7.0 7.4 3.6 7.6 0.1 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat DNA_alkylation PF08713.6 KKK18083.1 - 0.0032 17.0 0.7 0.0046 16.4 0.5 1.1 1 0 0 1 1 1 1 DNA alkylation repair enzyme BRF1 PF07741.8 KKK18083.1 - 0.11 12.7 7.9 0.25 11.5 5.5 1.7 1 0 0 1 1 1 0 Brf1-like TBP-binding domain DUF572 PF04502.8 KKK18083.1 - 2.9 7.0 9.9 4.7 6.3 6.8 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) Peptidase_M22 PF00814.20 KKK18084.1 - 2.6e-45 155.0 0.0 1.1e-43 149.7 0.0 2.5 1 1 0 1 1 1 1 Glycoprotease family FGGY_C PF02782.11 KKK18084.1 - 0.015 14.9 0.0 0.03 13.9 0.0 1.4 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain YycC PF14174.1 KKK18084.1 - 0.064 12.9 0.0 0.15 11.7 0.0 1.6 1 0 0 1 1 1 0 YycC-like protein Esterase PF00756.15 KKK18085.1 - 6.6e-55 186.2 0.0 7.9e-55 185.9 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.2 KKK18085.1 - 3.1e-06 27.0 0.0 4.1e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase_phd PF10503.4 KKK18085.1 - 8.3e-06 25.2 0.0 0.00027 20.2 0.0 2.0 2 0 0 2 2 2 1 Esterase PHB depolymerase Abhydrolase_6 PF12697.2 KKK18085.1 - 5.4e-05 23.1 0.0 6.9e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KKK18085.1 - 0.00032 19.9 0.1 0.00064 18.9 0.0 1.5 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 KKK18085.1 - 0.0045 16.5 0.0 0.28 10.6 0.0 2.2 1 1 1 2 2 2 1 alpha/beta hydrolase fold Lipase_3 PF01764.20 KKK18085.1 - 0.0063 16.1 0.0 0.01 15.4 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) AXE1 PF05448.7 KKK18085.1 - 0.011 14.2 0.0 0.016 13.7 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Chlorophyllase2 PF12740.2 KKK18085.1 - 0.012 14.5 0.0 0.024 13.5 0.0 1.5 1 1 0 1 1 1 0 Chlorophyllase enzyme PGAP1 PF07819.8 KKK18085.1 - 0.097 12.2 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein HMG_CoA_synt_C PF08540.5 KKK18086.1 - 1.3e-15 57.6 0.0 1.4e-15 57.5 0.0 1.0 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal EPL1 PF10513.4 KKK18088.1 - 2.3e-33 115.7 0.0 2.3e-33 115.7 0.0 2.2 2 1 0 2 2 2 1 Enhancer of polycomb-like zf-HC5HC2H_2 PF13832.1 KKK18088.1 - 3.9e-33 113.7 5.6 3.9e-33 113.7 3.9 2.3 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 KKK18088.1 - 1e-27 96.1 2.0 1e-27 96.1 1.4 2.9 3 0 0 3 3 3 1 PHD-like zinc-binding domain PHD_2 PF13831.1 KKK18088.1 - 2e-14 52.6 8.5 7.3e-14 50.7 1.7 2.6 2 0 0 2 2 2 1 PHD-finger PHD PF00628.24 KKK18088.1 - 8.5e-10 38.1 19.3 5.9e-08 32.2 6.7 2.6 2 0 0 2 2 2 2 PHD-finger zf-RING-like PF08746.6 KKK18088.1 - 0.013 15.4 2.5 0.013 15.4 1.7 2.6 2 0 0 2 2 2 0 RING-like domain C1_1 PF00130.17 KKK18088.1 - 0.74 9.5 18.5 0.029 14.1 0.9 2.8 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-PHD-like PF15446.1 KKK18088.1 - 2.1 7.6 10.3 0.043 13.0 2.0 1.9 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain Prok-RING_1 PF14446.1 KKK18088.1 - 2.9 7.6 14.8 1.8 8.3 4.2 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 RRM_1 PF00076.17 KKK18089.1 - 2.5e-21 75.0 0.0 3.3e-21 74.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KKK18089.1 - 2.8e-17 62.4 0.0 3.7e-17 62.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KKK18089.1 - 1.7e-12 46.9 0.0 2.3e-12 46.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AA_permease PF00324.16 KKK18098.1 - 1.8e-138 461.9 38.2 2e-138 461.7 26.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KKK18098.1 - 5.7e-30 104.1 40.7 7.7e-30 103.7 28.2 1.0 1 0 0 1 1 1 1 Amino acid permease RhoGAP PF00620.22 KKK18099.1 - 8.7e-16 57.8 0.1 1.9e-15 56.7 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.18 KKK18099.1 - 1e-11 44.8 0.0 5.2e-11 42.5 0.0 2.2 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain DEP PF00610.16 KKK18099.1 - 8.7e-11 41.4 0.0 1.7e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) AAA PF00004.24 KKK18100.1 - 5.3e-13 49.3 0.0 1.5e-12 47.8 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KKK18100.1 - 8.4e-13 48.7 2.2 1.9e-12 47.5 0.2 2.5 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KKK18100.1 - 2.7e-12 46.9 0.1 8e-12 45.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain Cdc6_C PF09079.6 KKK18100.1 - 1.9e-05 24.3 0.0 6.5e-05 22.5 0.0 1.9 1 0 0 1 1 1 1 CDC6, C terminal DUF2075 PF09848.4 KKK18100.1 - 0.0023 16.9 0.0 0.0042 16.1 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Arch_ATPase PF01637.13 KKK18100.1 - 0.0045 16.7 0.0 0.011 15.5 0.0 1.6 1 0 0 1 1 1 1 Archaeal ATPase AAA_11 PF13086.1 KKK18100.1 - 0.0092 15.5 0.0 0.038 13.5 0.0 2.2 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.8 KKK18100.1 - 0.011 14.6 0.0 0.023 13.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) NACHT PF05729.7 KKK18100.1 - 0.018 14.7 0.0 0.042 13.4 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_14 PF13173.1 KKK18100.1 - 0.02 14.7 0.0 0.073 12.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 KKK18100.1 - 0.021 14.5 0.0 0.04 13.6 0.0 1.5 1 0 0 1 1 1 0 NTPase PIF1 PF05970.9 KKK18100.1 - 0.022 13.7 0.0 0.036 13.0 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase AAA_19 PF13245.1 KKK18100.1 - 0.033 13.9 0.1 0.095 12.4 0.1 1.7 1 0 0 1 1 1 0 Part of AAA domain TIP49 PF06068.8 KKK18100.1 - 0.037 12.7 0.0 0.065 11.9 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus ABC_tran PF00005.22 KKK18100.1 - 0.041 14.1 0.0 0.15 12.3 0.0 2.0 2 0 0 2 2 1 0 ABC transporter AAA_5 PF07728.9 KKK18100.1 - 0.052 13.2 0.0 0.15 11.8 0.0 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.1 KKK18100.1 - 0.1 12.5 0.0 0.26 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 KKK18100.1 - 0.13 12.5 0.0 0.31 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain Pkinase PF00069.20 KKK18101.1 - 6e-30 104.2 0.0 6.7e-30 104.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK18101.1 - 5.2e-21 74.8 0.0 5.8e-21 74.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase ABC1 PF03109.11 KKK18101.1 - 0.069 13.1 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 ABC1 family UBA_4 PF14555.1 KKK18102.1 - 1.7e-14 53.0 0.1 3.6e-14 52.0 0.1 1.5 1 0 0 1 1 1 1 UBA-like domain Thioredoxin_7 PF13899.1 KKK18102.1 - 3.1e-14 52.7 0.0 5.9e-14 51.8 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like UBX PF00789.15 KKK18102.1 - 4.3e-06 26.6 0.0 2.6e-05 24.1 0.0 2.3 3 0 0 3 3 3 1 UBX domain Thioredoxin_2 PF13098.1 KKK18102.1 - 0.0017 18.5 0.0 0.0045 17.1 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredox_DsbH PF03190.10 KKK18102.1 - 0.017 14.8 0.0 0.029 14.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF255 Methyltransf_23 PF13489.1 KKK18122.1 - 3e-15 56.3 0.0 5.2e-15 55.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KKK18122.1 - 4.5e-06 27.2 0.0 1.4e-05 25.6 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KKK18122.1 - 2.1e-05 24.9 0.0 5.5e-05 23.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KKK18122.1 - 4.4e-05 23.8 0.0 0.00018 21.9 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KKK18122.1 - 0.00012 21.6 0.0 0.00029 20.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 KKK18122.1 - 0.00019 21.4 0.0 0.00046 20.2 0.0 1.6 2 0 0 2 2 2 1 FtsJ-like methyltransferase MTS PF05175.9 KKK18122.1 - 0.00023 20.5 0.0 0.00043 19.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.12 KKK18122.1 - 0.0012 17.9 0.0 0.0022 17.0 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_26 PF13659.1 KKK18122.1 - 0.0068 16.4 0.1 0.014 15.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KKK18122.1 - 0.018 15.3 0.0 0.12 12.7 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain PrmA PF06325.8 KKK18122.1 - 0.063 12.3 0.0 0.1 11.6 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.13 KKK18122.1 - 0.096 11.7 0.0 0.54 9.3 0.0 2.1 2 1 0 2 2 2 0 ubiE/COQ5 methyltransferase family CMAS PF02353.15 KKK18122.1 - 0.11 11.5 0.0 0.21 10.6 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_2 PF00891.13 KKK18122.1 - 0.15 11.2 0.1 1 8.5 0.0 2.0 2 0 0 2 2 2 0 O-methyltransferase Ig_2 PF13895.1 KKK18126.1 - 0.075 13.1 0.1 0.13 12.3 0.1 1.4 1 0 0 1 1 1 0 Immunoglobulin domain Glyoxalase PF00903.20 KKK18127.1 - 4.4e-32 110.7 0.0 1e-15 57.8 0.0 2.7 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 KKK18127.1 - 2.6e-28 98.7 0.0 3.1e-14 53.5 0.0 2.9 2 0 0 2 2 2 2 Glyoxalase-like domain Fungal_trans PF04082.13 KKK18127.1 - 1e-18 67.1 0.0 2.5e-18 65.9 0.0 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Glyoxalase_4 PF13669.1 KKK18127.1 - 6.3e-12 45.4 0.0 0.00013 21.9 0.0 3.8 2 2 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.1 KKK18127.1 - 0.00056 19.8 0.0 0.75 9.6 0.0 3.1 3 0 0 3 3 3 2 Glyoxalase-like domain SnoaL_4 PF13577.1 KKK18130.1 - 0.047 13.6 0.1 0.066 13.1 0.1 1.3 1 1 0 1 1 1 0 SnoaL-like domain DUF3435 PF11917.3 KKK18131.1 - 6.6e-12 44.8 0.0 8.6e-12 44.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) WD40 PF00400.27 KKK18158.1 - 1e-49 164.6 32.1 1.7e-09 37.1 2.4 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 KKK18158.1 - 0.00044 20.0 0.4 0.11 12.2 0.1 2.6 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A MBOAT PF03062.14 KKK18159.1 - 4.6e-26 91.7 12.4 8e-26 90.9 8.6 1.4 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.1 KKK18159.1 - 0.34 11.0 5.9 0.23 11.5 2.4 2.1 2 0 0 2 2 2 0 Membrane bound O-acyl transferase family Tmemb_170 PF10190.4 KKK18161.1 - 4.4e-05 23.4 5.3 5.6e-05 23.1 3.7 1.1 1 0 0 1 1 1 1 Putative transmembrane protein 170 ABC2_membrane_4 PF12730.2 KKK18161.1 - 0.93 8.6 9.1 4.1 6.4 6.3 1.8 1 1 0 1 1 1 0 ABC-2 family transporter protein TFIIE_alpha PF02002.12 KKK18162.1 - 2.1e-18 65.7 0.0 5.9e-18 64.3 0.0 1.8 1 0 0 1 1 1 1 TFIIE alpha subunit Zn-ribbon_8 PF09723.5 KKK18162.1 - 0.041 13.8 0.1 0.1 12.5 0.1 1.7 1 0 0 1 1 1 0 Zinc ribbon domain TF_Zn_Ribbon PF08271.7 KKK18162.1 - 0.053 12.8 2.3 1.2 8.4 1.6 2.5 1 1 1 2 2 2 0 TFIIB zinc-binding HTH_Crp_2 PF13545.1 KKK18162.1 - 0.13 12.1 0.1 0.35 10.7 0.1 1.7 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain DUF3517 PF12030.3 KKK18163.1 - 8.5e-174 576.8 0.1 2.1e-173 575.5 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3517) UCH PF00443.24 KKK18163.1 - 2e-47 161.5 0.5 3.3e-47 160.8 0.4 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KKK18163.1 - 7.8e-17 61.6 1.5 1.4e-16 60.7 0.1 2.0 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase PseudoU_synth_1 PF01416.15 KKK18164.1 - 5.1e-17 62.2 0.0 1.5e-08 34.9 0.0 2.6 2 0 0 2 2 2 2 tRNA pseudouridine synthase MCPVI PF02993.9 KKK18164.1 - 2.3 8.3 4.5 0.79 9.8 0.9 1.8 2 0 0 2 2 2 0 Minor capsid protein VI Mac PF12464.3 KKK18165.1 - 2.2e-15 56.4 0.1 3.3e-15 55.8 0.0 1.3 1 0 0 1 1 1 1 Maltose acetyltransferase Hexapep PF00132.19 KKK18165.1 - 5.5e-15 54.0 7.0 4.6e-11 41.7 2.9 3.2 2 1 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 KKK18165.1 - 1.3e-11 43.8 8.1 6.2e-10 38.4 2.3 3.2 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase ICMT PF04140.9 KKK18166.1 - 9.4e-29 99.4 0.5 2.1e-28 98.3 0.3 1.6 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 KKK18166.1 - 9.2e-15 54.6 1.7 2.3e-14 53.4 1.2 1.7 1 0 0 1 1 1 1 Phospholipid methyltransferase DUF1295 PF06966.7 KKK18166.1 - 0.00033 20.0 0.6 0.00047 19.5 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) NnrU PF07298.6 KKK18166.1 - 0.0035 16.7 6.5 0.0052 16.1 4.5 1.3 1 0 0 1 1 1 1 NnrU protein OMPdecase PF00215.19 KKK18167.1 - 3.6e-77 258.7 0.0 5e-77 258.3 0.0 1.2 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family MAPEG PF01124.13 KKK18167.1 - 1.8e-23 82.5 0.2 3.1e-23 81.7 0.1 1.3 1 0 0 1 1 1 1 MAPEG family DUF2809 PF10990.3 KKK18170.1 - 3.5 8.1 8.8 0.69 10.3 0.3 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF2809) UTP15_C PF09384.5 KKK18171.1 - 8.8e-52 174.7 0.5 1.6e-51 173.8 0.4 1.4 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.27 KKK18171.1 - 1.4e-28 97.6 5.3 1.2e-07 31.3 0.1 4.8 5 0 0 5 5 5 4 WD domain, G-beta repeat PQQ_2 PF13360.1 KKK18171.1 - 0.0011 18.4 0.2 0.01 15.3 0.0 2.2 1 1 1 2 2 2 1 PQQ-like domain PhyH PF05721.8 KKK18172.1 - 3.3e-44 151.4 0.0 8.7e-42 143.5 0.0 2.1 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Nuc_recep-AF1 PF11825.3 KKK18172.1 - 0.029 14.2 1.8 0.053 13.4 1.3 1.3 1 0 0 1 1 1 0 Nuclear/hormone receptor activator site AF-1 C2 PF00168.25 KKK18173.1 - 1e-10 41.3 0.1 1.9e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 C2 domain DUF3439 PF11921.3 KKK18173.1 - 1.7 8.3 7.1 4 7.1 4.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Ank_2 PF12796.2 KKK18174.1 - 5.6e-49 164.4 4.8 1.6e-19 70.0 0.0 4.3 2 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KKK18174.1 - 2.7e-28 97.8 2.1 2.9e-11 43.5 0.1 6.4 5 2 2 7 7 7 4 Ankyrin repeats (many copies) Ank PF00023.25 KKK18174.1 - 6.8e-25 85.5 5.1 1.4e-08 34.0 0.1 7.1 8 0 0 8 8 8 5 Ankyrin repeat Ank_3 PF13606.1 KKK18174.1 - 3.1e-23 79.5 2.5 3.5e-06 26.7 0.0 8.2 8 0 0 8 8 8 4 Ankyrin repeat Ank_5 PF13857.1 KKK18174.1 - 6e-20 70.8 4.2 3e-10 39.9 0.2 5.2 4 1 1 5 5 5 4 Ankyrin repeats (many copies) RRM_6 PF14259.1 KKK18175.1 - 1e-05 25.3 0.0 1.8e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KKK18175.1 - 2e-05 24.1 0.0 3.6e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KKK18175.1 - 0.00017 21.3 0.0 0.00037 20.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Lsm_interact PF05391.6 KKK18175.1 - 0.00085 18.6 0.9 0.00085 18.6 0.6 1.8 2 0 0 2 2 2 1 Lsm interaction motif DUF1616 PF07760.6 KKK18176.1 - 0.038 13.1 0.2 0.038 13.1 0.1 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1616) UPF0546 PF10639.4 KKK18177.1 - 7e-30 103.1 1.1 1.1e-29 102.4 0.8 1.3 1 0 0 1 1 1 1 Uncharacterised protein family UPF0546 EmrE PF13536.1 KKK18177.1 - 0.15 12.2 3.5 0.26 11.4 2.4 1.5 1 1 0 1 1 1 0 Multidrug resistance efflux transporter Mito_fiss_reg PF05308.6 KKK18177.1 - 0.73 9.1 7.2 0.93 8.8 5.0 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator EamA PF00892.15 KKK18177.1 - 0.95 9.5 8.0 0.21 11.6 3.5 1.5 2 0 0 2 2 2 0 EamA-like transporter family CAP_N PF01213.14 KKK18177.1 - 5 6.3 6.2 6.2 6.0 4.3 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Chitin_synth_1 PF01644.12 KKK18178.1 - 8.9e-82 272.7 0.1 1.8e-81 271.7 0.0 1.6 2 0 0 2 2 2 1 Chitin synthase Chitin_synth_1N PF08407.6 KKK18178.1 - 7.2e-31 105.7 0.0 1.4e-30 104.7 0.0 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 KKK18178.1 - 2.2e-21 75.8 2.4 2.1e-17 62.7 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 KKK18178.1 - 1.4e-08 34.7 4.4 1.4e-08 34.7 3.0 2.5 3 1 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 KKK18178.1 - 7.8e-08 32.3 0.0 4.7e-07 29.8 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Pkinase PF00069.20 KKK18179.1 - 2.6e-31 108.7 0.0 1.9e-16 60.0 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KKK18179.1 - 5.1e-07 29.0 0.0 0.0063 15.6 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 KKK18179.1 - 0.091 12.4 0.1 0.32 10.6 0.1 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family LMWPc PF01451.16 KKK18180.1 - 1.7e-30 106.1 0.0 2.2e-30 105.8 0.0 1.1 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase COQ7 PF03232.8 KKK18181.1 - 1.4e-62 210.1 0.3 1.7e-62 209.8 0.2 1.1 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Rubrerythrin PF02915.12 KKK18181.1 - 8.9e-06 26.0 0.2 2.9e-05 24.3 0.1 1.8 1 1 0 1 1 1 1 Rubrerythrin DUF1817 PF08847.6 KKK18181.1 - 0.03 13.8 0.0 1.2 8.6 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF1817) SPT2 PF08243.6 KKK18181.1 - 0.98 9.7 4.5 1.6 9.0 3.1 1.3 1 0 0 1 1 1 0 SPT2 chromatin protein Plus-3 PF03126.13 KKK18182.1 - 2.9e-32 110.9 0.0 1.7e-31 108.4 0.0 2.2 2 0 0 2 2 2 1 Plus-3 domain MRC1 PF09444.5 KKK18183.1 - 1.7e-43 148.3 17.1 1.7e-43 148.3 11.8 6.7 5 3 1 6 6 6 1 MRC1-like domain KR PF08659.5 KKK18183.1 - 1.6 8.3 5.4 0.82 9.2 1.0 2.3 2 0 0 2 2 2 0 KR domain CorA PF01544.13 KKK18192.1 - 1e-38 133.0 0.2 2e-38 132.1 0.1 1.4 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Fungal_trans PF04082.13 KKK18221.1 - 1.2e-18 66.9 0.1 2.3e-18 66.0 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain FAD_binding_3 PF01494.14 KKK18222.1 - 5.4e-17 61.8 0.2 1.7e-07 30.6 0.0 3.2 3 0 0 3 3 3 3 FAD binding domain NAD_binding_8 PF13450.1 KKK18222.1 - 0.0013 18.6 0.0 0.0032 17.4 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain SE PF08491.5 KKK18222.1 - 0.0014 17.5 0.0 0.029 13.1 0.0 2.1 2 0 0 2 2 2 1 Squalene epoxidase Pyr_redox_3 PF13738.1 KKK18222.1 - 0.0073 16.3 0.0 0.01 15.9 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KKK18222.1 - 0.016 14.9 0.0 0.029 14.1 0.0 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding Myb_DNA-bind_6 PF13921.1 KKK18223.1 - 1.8e-27 95.2 11.2 1.3e-14 54.0 1.8 3.3 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 KKK18223.1 - 6.2e-26 90.1 14.7 1.8e-11 43.9 0.8 3.7 4 0 0 4 4 4 3 Myb-like DNA-binding domain Myb_DNA-bind_5 PF13873.1 KKK18223.1 - 0.35 10.7 8.4 35 4.3 0.0 4.4 3 2 1 4 4 4 0 Myb/SANT-like DNA-binding domain NDUFA12 PF05071.11 KKK18223.1 - 0.56 10.6 4.3 0.53 10.7 1.7 1.9 2 0 0 2 2 2 0 NADH ubiquinone oxidoreductase subunit NDUFA12 HsbA PF12296.3 KKK18224.1 - 2.6e-27 95.1 8.8 2.6e-27 95.1 6.1 2.4 2 0 0 2 2 2 1 Hydrophobic surface binding protein A Fungal_trans PF04082.13 KKK18225.1 - 2.1e-21 76.0 0.5 3e-21 75.4 0.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Cutinase PF01083.17 KKK18226.1 - 3.8e-52 176.6 2.5 4.4e-52 176.4 1.7 1.0 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.6 KKK18226.1 - 0.00045 19.7 0.1 0.00065 19.1 0.0 1.2 1 0 0 1 1 1 1 PE-PPE domain VirJ PF06057.6 KKK18226.1 - 0.00066 19.5 0.0 0.00095 18.9 0.0 1.2 1 0 0 1 1 1 1 Bacterial virulence protein (VirJ) LVIVD PF08309.6 KKK18227.1 - 1e-12 46.8 1.7 0.11 11.4 0.0 5.4 5 0 0 5 5 5 5 LVIVD repeat Brr6_like_C_C PF10104.4 KKK18228.1 - 5.4e-43 145.7 0.1 7.1e-43 145.3 0.1 1.1 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain Corona_RPol_N PF06478.8 KKK18228.1 - 0.03 13.0 0.0 0.043 12.5 0.0 1.1 1 0 0 1 1 1 0 Coronavirus RPol N-terminus Lipase_GDSL_2 PF13472.1 KKK18229.1 - 1.3e-09 38.4 0.6 3.2e-09 37.1 0.2 1.8 2 1 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 KKK18229.1 - 1.3e-05 25.1 0.1 2.5e-05 24.2 0.1 1.5 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.1 KKK18229.1 - 0.00072 19.3 0.0 0.0013 18.4 0.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Ank_2 PF12796.2 KKK18230.1 - 1.5e-42 143.8 0.1 8.3e-21 74.1 0.0 4.0 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 KKK18230.1 - 2.7e-39 131.0 1.1 1.3e-07 31.0 0.0 7.4 7 0 0 7 7 7 7 Ankyrin repeat Ank_5 PF13857.1 KKK18230.1 - 2.4e-34 116.5 6.8 5.9e-10 39.0 0.1 6.1 2 1 5 7 7 7 6 Ankyrin repeats (many copies) Ank_4 PF13637.1 KKK18230.1 - 4.1e-27 94.0 2.9 8.7e-06 26.1 0.0 6.2 2 2 5 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 KKK18230.1 - 4.9e-26 88.1 0.4 0.00044 20.2 0.0 7.4 7 0 0 7 7 7 6 Ankyrin repeat F-box-like PF12937.2 KKK18230.1 - 0.033 13.9 0.1 0.068 12.9 0.1 1.6 1 0 0 1 1 1 0 F-box-like DUF1811 PF08838.5 KKK18231.1 - 0.019 14.9 0.3 0.029 14.3 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1811) DUF2076 PF09849.4 KKK18233.1 - 9.6e-06 25.8 1.0 9.6e-06 25.8 0.7 2.6 2 1 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2076) DUF1183 PF06682.7 KKK18233.1 - 0.02 14.5 1.1 0.02 14.5 0.8 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1183) ETRAMP PF09716.5 KKK18233.1 - 0.095 12.6 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) DUF4366 PF14283.1 KKK18233.1 - 0.13 11.7 0.9 0.18 11.1 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Zip PF02535.17 KKK18233.1 - 2.8 6.8 7.0 0.16 10.9 0.8 1.7 2 0 0 2 2 2 0 ZIP Zinc transporter Terpene_synth_C PF03936.11 KKK18234.1 - 0.0017 17.6 0.8 0.018 14.2 0.1 2.5 2 1 0 2 2 2 1 Terpene synthase family, metal binding domain Methyltransf_31 PF13847.1 KKK18235.1 - 1.6e-26 92.7 0.0 2e-26 92.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KKK18235.1 - 4.4e-24 84.8 0.0 6.5e-24 84.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KKK18235.1 - 4.7e-16 58.6 0.0 6.6e-16 58.1 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 KKK18235.1 - 2.4e-15 56.8 0.0 3.5e-15 56.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KKK18235.1 - 3.1e-15 56.7 0.0 5.3e-15 55.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KKK18235.1 - 4.4e-15 55.8 0.0 7.1e-15 55.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KKK18235.1 - 3.8e-14 52.7 0.0 4.7e-14 52.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KKK18235.1 - 3.8e-10 39.8 0.1 6.8e-10 39.0 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 KKK18235.1 - 4e-09 36.1 0.0 5.8e-09 35.5 0.0 1.1 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW PCMT PF01135.14 KKK18235.1 - 1.7e-08 34.2 0.0 2.4e-08 33.7 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.9 KKK18235.1 - 9e-07 28.4 0.0 1.3e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain DREV PF05219.7 KKK18235.1 - 9.2e-06 24.7 0.0 1.3e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 DREV methyltransferase NodS PF05401.6 KKK18235.1 - 0.00016 21.1 0.0 0.00023 20.6 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_9 PF08003.6 KKK18235.1 - 0.00022 20.0 0.0 0.00031 19.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_4 PF02390.12 KKK18235.1 - 0.00028 19.9 0.0 0.00038 19.5 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_29 PF03141.11 KKK18235.1 - 0.0012 17.2 0.0 0.0016 16.8 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase RrnaAD PF00398.15 KKK18235.1 - 0.0016 17.4 0.0 0.0022 17.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase CMAS PF02353.15 KKK18235.1 - 0.03 13.4 0.0 0.038 13.0 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Flavoprotein PF02441.14 KKK18236.1 - 1.3e-30 105.7 0.2 1.8e-30 105.2 0.1 1.1 1 0 0 1 1 1 1 Flavoprotein Na_Ca_ex PF01699.19 KKK18237.1 - 8.5e-33 112.9 34.0 5e-20 71.5 8.7 2.6 2 1 0 2 2 2 2 Sodium/calcium exchanger protein UbiD PF01977.11 KKK18238.1 - 7.6e-130 433.0 0.0 9e-130 432.7 0.0 1.0 1 0 0 1 1 1 1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase DUF3756 PF12581.3 KKK18238.1 - 0.13 11.9 0.1 18 5.0 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3756) EthD PF07110.6 KKK18278.1 - 9.6e-23 80.9 1.2 1.1e-22 80.7 0.8 1.0 1 0 0 1 1 1 1 EthD domain Chlor_dismutase PF06778.7 KKK18278.1 - 0.04 13.6 0.0 0.055 13.1 0.0 1.2 1 0 0 1 1 1 0 Chlorite dismutase CBS PF00571.23 KKK18281.1 - 9.6e-05 22.1 0.0 0.48 10.2 0.0 3.1 2 1 0 2 2 2 2 CBS domain Apc4 PF12896.2 KKK18281.1 - 0.15 11.3 0.0 0.24 10.7 0.0 1.2 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 4 VMA21 PF09446.5 KKK18282.1 - 7.4e-16 57.8 12.1 9.8e-16 57.4 8.4 1.2 1 0 0 1 1 1 1 VMA21-like domain MS_channel PF00924.13 KKK18282.1 - 0.01 15.2 2.6 0.014 14.7 1.8 1.1 1 0 0 1 1 1 1 Mechanosensitive ion channel UPF0104 PF03706.8 KKK18282.1 - 0.012 14.9 0.0 0.014 14.6 0.0 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0104) NfeD PF01957.13 KKK18282.1 - 0.07 13.2 0.6 0.087 12.9 0.4 1.1 1 0 0 1 1 1 0 NfeD-like C-terminal, partner-binding DUF4407 PF14362.1 KKK18282.1 - 0.071 12.0 0.2 0.087 11.7 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Vpu PF00558.14 KKK18282.1 - 0.12 11.9 0.9 0.18 11.3 0.0 1.6 2 0 0 2 2 2 0 Vpu protein ABC2_membrane_2 PF12679.2 KKK18282.1 - 6.9 5.4 8.3 8.5 5.1 5.7 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein Sugar_tr PF00083.19 KKK18283.1 - 2.6e-93 313.0 30.6 3e-93 312.8 21.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KKK18283.1 - 7.7e-28 97.2 45.6 2.3e-24 85.7 14.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KKK18283.1 - 0.00048 18.4 1.6 0.00048 18.4 1.1 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) YrhC PF14143.1 KKK18283.1 - 0.067 13.1 0.1 0.067 13.1 0.1 2.8 4 0 0 4 4 4 0 YrhC-like protein SNF2_N PF00176.18 KKK18284.1 - 3e-62 210.1 0.3 4.7e-62 209.4 0.2 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KKK18284.1 - 3.1e-14 52.5 0.0 9e-14 51.1 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KKK18284.1 - 4.9e-07 29.7 0.0 1e-06 28.7 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 KKK18284.1 - 5.3e-07 29.2 0.0 1e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase HHH_3 PF12836.2 KKK18284.1 - 0.012 15.5 0.0 0.031 14.2 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif CLP_protease PF00574.18 KKK18285.1 - 3.9e-75 251.5 0.0 4.9e-75 251.1 0.0 1.1 1 0 0 1 1 1 1 Clp protease Peptidase_S49 PF01343.13 KKK18285.1 - 0.073 12.8 0.0 0.16 11.7 0.0 1.5 1 1 0 1 1 1 0 Peptidase family S49 Hydrolase_like PF13242.1 KKK18287.1 - 3.7e-12 45.7 0.0 2.2e-11 43.2 0.0 2.0 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.21 KKK18287.1 - 1.7e-05 25.3 0.0 3.2e-05 24.4 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 KKK18287.1 - 0.002 17.9 0.2 0.017 14.9 0.0 2.3 1 1 1 2 2 2 1 Haloacid dehalogenase-like hydrolase Sec20 PF03908.8 KKK18288.1 - 1.2e-16 60.2 1.0 1.2e-16 60.2 0.7 2.3 3 0 0 3 3 2 1 Sec20 AAA PF00004.24 KKK18288.1 - 2.1e-14 53.8 0.0 8.2e-14 51.9 0.0 2.1 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 KKK18288.1 - 1.1e-13 51.2 0.1 7.8e-13 48.3 0.0 2.5 2 1 0 2 2 2 1 DNA polymerase III, delta subunit Rad17 PF03215.10 KKK18288.1 - 3.9e-10 39.0 0.1 4.5e-08 32.2 0.0 2.3 1 1 0 2 2 2 1 Rad17 cell cycle checkpoint protein Rep_fac_C PF08542.6 KKK18288.1 - 9.5e-10 38.3 0.0 2.6e-09 36.9 0.0 1.8 1 0 0 1 1 1 1 Replication factor C C-terminal domain RuvB_N PF05496.7 KKK18288.1 - 2.6e-06 26.6 0.0 6.8e-06 25.2 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 KKK18288.1 - 4.8e-05 23.4 0.1 0.00085 19.4 0.0 2.9 2 1 0 2 2 1 1 AAA domain AAA_11 PF13086.1 KKK18288.1 - 6.7e-05 22.5 4.5 0.001 18.7 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KKK18288.1 - 0.00016 21.3 0.0 0.0005 19.7 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_14 PF13173.1 KKK18288.1 - 0.00017 21.4 0.0 0.00047 20.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 KKK18288.1 - 0.00081 18.5 0.0 0.024 13.8 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.1 KKK18288.1 - 0.00092 19.2 6.1 0.0052 16.7 0.0 3.9 3 1 1 4 4 4 1 AAA ATPase domain AAA_24 PF13479.1 KKK18288.1 - 0.0025 17.4 0.2 0.0097 15.5 0.2 2.0 1 0 0 1 1 1 1 AAA domain PhoH PF02562.11 KKK18288.1 - 0.0067 15.6 0.6 13 4.9 0.0 3.6 3 1 0 3 3 3 0 PhoH-like protein FtsK_SpoIIIE PF01580.13 KKK18288.1 - 0.0091 15.4 0.6 0.03 13.7 0.0 2.2 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_25 PF13481.1 KKK18288.1 - 0.02 14.2 0.1 0.1 12.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 KKK18288.1 - 0.031 14.5 8.1 0.037 14.3 0.0 2.9 2 1 0 2 2 1 0 AAA domain AAA_5 PF07728.9 KKK18288.1 - 0.04 13.6 0.1 0.41 10.3 0.1 2.5 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 KKK18288.1 - 0.046 14.5 0.3 0.41 11.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain DNA_pol3_delta PF06144.8 KKK18288.1 - 0.076 12.5 0.0 0.23 10.9 0.0 1.8 1 0 0 1 1 1 0 DNA polymerase III, delta subunit MutS_II PF05188.12 KKK18288.1 - 0.61 10.1 4.3 1.2 9.2 2.5 1.9 1 1 0 1 1 1 0 MutS domain II Mito_carr PF00153.22 KKK18289.1 - 1.3e-48 162.6 6.9 1.8e-17 62.8 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF3602 PF12223.3 KKK18290.1 - 2.3e-11 43.8 8.3 2.9e-10 40.3 0.3 3.0 1 1 2 3 3 3 2 Protein of unknown function (DUF3602) Ribosomal_L35Ae PF01247.13 KKK18291.1 - 1.6e-41 139.9 0.4 1.9e-41 139.7 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.13 KKK18291.1 - 0.0037 17.1 0.1 1.4 8.9 0.0 2.1 2 0 0 2 2 2 2 RimM N-terminal domain DUF2080 PF09853.4 KKK18291.1 - 0.17 11.6 1.1 1.2 8.9 0.1 2.2 1 1 1 2 2 2 0 Putative transposon-encoded protein (DUF2080) G6PD_C PF02781.11 KKK18292.1 - 2.6e-136 453.2 0.0 3.6e-136 452.7 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.17 KKK18292.1 - 8.7e-64 215.1 0.0 1.5e-63 214.3 0.0 1.4 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain DUF2406 PF10295.4 KKK18293.1 - 6.2e-22 77.8 2.8 6.7e-21 74.5 0.0 3.0 2 0 0 2 2 2 1 Uncharacterised protein (DUF2406) DivIC PF04977.10 KKK18293.1 - 4.3 6.8 7.2 0.66 9.4 2.2 1.6 2 0 0 2 2 2 0 Septum formation initiator 4HBT_2 PF13279.1 KKK18294.1 - 5.7e-05 23.5 0.0 0.00011 22.6 0.0 1.5 1 0 0 1 1 1 1 Thioesterase-like superfamily MFS_2 PF13347.1 KKK18295.1 - 4e-15 55.1 11.1 4e-15 55.1 7.7 1.7 1 1 0 1 1 1 1 MFS/sugar transport protein DUF1228 PF06779.9 KKK18295.1 - 0.031 14.3 4.4 1.2 9.1 0.4 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1228) DUF2569 PF10754.4 KKK18295.1 - 0.089 13.0 0.2 0.089 13.0 0.1 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF2569) MFS_1_like PF12832.2 KKK18295.1 - 0.1 12.4 0.0 0.1 12.4 0.0 3.8 3 1 0 3 3 3 0 MFS_1 like family DUF1708 PF08101.6 KKK18296.1 - 2.3e-154 514.2 0.0 3.3e-154 513.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1708) RhoGAP PF00620.22 KKK18296.1 - 0.016 14.8 0.0 0.061 12.9 0.0 1.9 2 0 0 2 2 2 0 RhoGAP domain NmrA PF05368.8 KKK18309.1 - 4.7e-58 196.2 0.2 5.7e-58 195.9 0.2 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KKK18309.1 - 2.2e-13 50.6 0.1 3e-13 50.1 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 KKK18309.1 - 3.4e-05 22.6 0.4 5.7e-05 21.9 0.3 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.13 KKK18309.1 - 0.012 15.5 0.1 0.022 14.7 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain Arb2 PF09757.4 KKK18310.1 - 2.5e-34 118.2 0.0 3.3e-34 117.8 0.0 1.1 1 0 0 1 1 1 1 Arb2 domain Phage_T4_Gp30_7 PF06919.6 KKK18310.1 - 0.074 13.0 0.1 14 5.6 0.0 2.2 2 0 0 2 2 2 0 Phage Gp30.7 protein Ribosomal_S14 PF00253.16 KKK18311.1 - 3.5e-18 64.7 0.2 3.8e-17 61.4 0.0 2.0 2 0 0 2 2 2 1 Ribosomal protein S14p/S29e DASH_Spc19 PF08287.6 KKK18312.1 - 9.8e-56 187.6 5.3 1.3e-55 187.2 3.6 1.1 1 0 0 1 1 1 1 Spc19 IFP_35_N PF07334.8 KKK18312.1 - 1.1 9.2 4.1 5.7 6.9 1.9 2.3 2 0 0 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus COG5 PF10392.4 KKK18312.1 - 2 8.3 6.7 7.1 6.6 0.3 2.9 2 1 1 3 3 3 0 Golgi transport complex subunit 5 Rogdi_lz PF10259.4 KKK18313.1 - 3.2e-75 252.7 0.0 4.8e-75 252.1 0.0 1.2 1 0 0 1 1 1 1 Rogdi leucine zipper containing protein Rsm22 PF09243.5 KKK18313.1 - 2.4e-29 102.2 0.0 1.2e-28 99.9 0.0 2.0 1 1 0 1 1 1 1 Mitochondrial small ribosomal subunit Rsm22 SUR7 PF06687.7 KKK18314.1 - 7.1e-41 140.0 12.7 8.2e-41 139.8 8.8 1.0 1 0 0 1 1 1 1 SUR7/PalI family Claudin_2 PF13903.1 KKK18314.1 - 0.0027 17.4 9.2 0.0027 17.4 6.4 2.1 1 1 1 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction Clc-like PF07062.7 KKK18314.1 - 0.0076 15.5 3.0 0.012 14.8 2.1 1.4 1 0 0 1 1 1 1 Clc-like GerA PF03323.8 KKK18314.1 - 1 7.4 3.2 1.7 6.6 2.2 1.3 1 0 0 1 1 1 0 Bacillus/Clostridium GerA spore germination protein Fig1 PF12351.3 KKK18314.1 - 1.1 9.0 14.3 0.26 11.1 7.4 1.9 1 1 1 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 DUF4064 PF13273.1 KKK18314.1 - 1.8 8.6 12.0 12 6.0 6.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF4064) Vma12 PF11712.3 KKK18315.1 - 3.5e-41 140.2 0.0 6.1e-41 139.4 0.0 1.4 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase PGA2 PF07543.7 KKK18315.1 - 0.47 10.2 10.4 0.86 9.3 7.2 1.3 1 0 0 1 1 1 0 Protein trafficking PGA2 PsbN PF02468.10 KKK18315.1 - 1.3 8.6 3.7 0.58 9.8 0.2 2.0 2 0 0 2 2 2 0 Photosystem II reaction centre N protein (psbN) Amidohydro_1 PF01979.15 KKK18316.1 - 9.3e-22 78.1 0.0 2.2e-20 73.5 0.0 2.4 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 KKK18316.1 - 3.6e-19 69.8 0.3 3.6e-18 66.5 0.2 2.3 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 KKK18316.1 - 5.9e-09 35.6 0.1 1.7e-08 34.1 0.1 1.7 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 KKK18316.1 - 7.6e-08 31.9 0.0 0.00018 20.8 0.0 2.5 2 1 0 2 2 2 2 Amidohydrolase family Glyco_hydro_26 PF02156.10 KKK18316.1 - 0.16 11.4 0.0 0.3 10.5 0.0 1.4 2 0 0 2 2 2 0 Glycosyl hydrolase family 26 Pyr_redox_2 PF07992.9 KKK18317.1 - 2.4e-41 141.8 12.6 4.8e-39 134.3 8.7 4.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 KKK18317.1 - 2.8e-40 136.7 0.2 9.2e-40 135.1 0.1 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 KKK18317.1 - 8.2e-23 80.6 10.6 4.3e-21 75.1 0.6 3.3 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KKK18317.1 - 1.3e-10 41.1 5.0 6.3e-06 26.1 0.4 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 KKK18317.1 - 2.7e-10 40.6 0.9 6.2e-06 26.4 0.1 2.4 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KKK18317.1 - 3e-10 39.5 15.7 0.00011 21.2 0.1 4.2 3 1 1 4 4 4 3 FAD dependent oxidoreductase FAD_oxidored PF12831.2 KKK18317.1 - 4.1e-10 39.3 9.8 6e-10 38.7 0.2 2.9 2 1 1 3 3 3 1 FAD dependent oxidoreductase GIDA PF01134.17 KKK18317.1 - 3.3e-09 36.0 14.0 7.7e-08 31.5 3.0 3.2 2 2 1 3 3 3 2 Glucose inhibited division protein A FAD_binding_2 PF00890.19 KKK18317.1 - 1.8e-07 30.3 2.0 1.8e-07 30.3 1.4 2.6 2 1 0 2 2 2 1 FAD binding domain K_oxygenase PF13434.1 KKK18317.1 - 3.3e-06 26.2 1.0 0.057 12.3 0.0 2.8 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.9 KKK18317.1 - 4.1e-06 25.5 14.4 0.0003 19.4 1.1 4.1 4 0 0 4 4 4 2 HI0933-like protein AlaDh_PNT_C PF01262.16 KKK18317.1 - 5e-06 26.1 3.1 0.0018 17.8 0.1 3.1 3 0 0 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.12 KKK18317.1 - 2.2e-05 23.6 8.6 0.00017 20.7 0.7 2.5 1 1 0 2 2 2 2 Thi4 family THF_DHG_CYH_C PF02882.14 KKK18317.1 - 0.0024 16.9 1.1 0.25 10.3 0.0 3.9 3 2 1 4 4 4 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3HCDH_N PF02737.13 KKK18317.1 - 0.0079 15.8 5.7 0.011 15.3 0.9 2.7 3 0 0 3 3 3 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_3 PF01494.14 KKK18317.1 - 0.0082 15.2 12.1 0.2 10.7 0.5 3.3 2 1 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.7 KKK18317.1 - 0.013 14.4 3.0 0.15 10.9 0.0 2.6 3 1 0 3 3 3 0 Lycopene cyclase protein DUF711 PF05167.7 KKK18317.1 - 0.027 13.1 0.2 0.057 12.1 0.0 1.6 2 0 0 2 2 2 0 Uncharacterised ACR (DUF711) FMO-like PF00743.14 KKK18317.1 - 0.096 10.8 2.8 2.7 6.0 0.5 2.8 3 0 0 3 3 3 0 Flavin-binding monooxygenase-like Trp_halogenase PF04820.9 KKK18317.1 - 0.11 11.1 5.6 0.27 9.8 0.4 2.3 2 0 0 2 2 2 0 Tryptophan halogenase Amino_oxidase PF01593.19 KKK18317.1 - 0.18 10.8 0.7 0.36 9.8 0.0 1.8 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase NAD_binding_7 PF13241.1 KKK18317.1 - 0.24 11.6 0.1 0.24 11.6 0.1 2.9 3 1 0 3 3 2 0 Putative NAD(P)-binding UDPG_MGDP_dh_N PF03721.9 KKK18317.1 - 0.87 8.9 5.3 1.6 8.0 0.3 2.7 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_10 PF13460.1 KKK18317.1 - 0.97 9.4 4.3 1 9.3 0.0 2.6 2 1 1 3 3 2 0 NADH(P)-binding PGM_PMM_I PF02878.11 KKK18318.1 - 5.8e-32 110.0 0.0 1.1e-31 109.1 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 KKK18318.1 - 2.5e-22 79.1 0.0 9.1e-22 77.3 0.0 1.9 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.11 KKK18318.1 - 3e-14 53.0 0.0 6.3e-14 51.9 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.15 KKK18318.1 - 4.2e-07 29.8 0.0 2.1e-06 27.6 0.0 2.1 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain HTH_20 PF12840.2 KKK18318.1 - 0.092 12.5 0.0 0.25 11.1 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain SecE PF00584.15 KKK18319.1 - 1.1e-10 40.9 0.0 1.2e-10 40.7 0.0 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex Sugar_tr PF00083.19 KKK18320.1 - 2.1e-83 280.4 23.5 2.4e-83 280.2 16.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KKK18320.1 - 2.8e-21 75.6 47.5 9.2e-17 60.7 13.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily zf-C2H2 PF00096.21 KKK18321.1 - 3.1e-10 39.7 6.8 1.3e-07 31.5 0.2 3.2 2 1 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KKK18321.1 - 1.4e-09 37.5 5.9 8.6e-06 25.7 0.1 3.0 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KKK18321.1 - 0.027 14.5 0.1 0.069 13.3 0.0 1.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.1 KKK18321.1 - 0.032 14.5 0.7 0.032 14.5 0.5 3.4 3 0 0 3 3 3 0 Zinc-finger double domain zf-met PF12874.2 KKK18321.1 - 0.088 13.0 2.5 0.14 12.4 0.0 2.4 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 KKK18321.1 - 0.74 9.8 6.4 1.4 8.8 0.0 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger DNA_binding_1 PF01035.15 KKK18322.1 - 1.2e-25 89.1 0.0 2.6e-25 87.9 0.0 1.6 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain FA_desaturase PF00487.19 KKK18324.1 - 8.6e-38 130.2 30.2 1.3e-37 129.6 20.9 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 KKK18324.1 - 5.8e-10 38.8 0.0 1.3e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Ribosomal_S10 PF00338.17 KKK18325.1 - 5.8e-27 93.3 0.3 6.9e-27 93.1 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e CUE PF02845.11 KKK18326.1 - 1.9e-06 27.2 0.0 5.1e-06 25.8 0.0 1.8 1 0 0 1 1 1 1 CUE domain SMC_N PF02463.14 KKK18327.1 - 1.3e-80 269.7 0.0 2.3e-80 268.9 0.0 1.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 KKK18327.1 - 3e-27 94.9 0.1 9.7e-27 93.3 0.0 2.0 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 KKK18327.1 - 1.1e-13 51.7 6.8 5.5e-07 29.8 0.2 3.3 3 1 0 3 3 3 2 AAA domain AAA_23 PF13476.1 KKK18327.1 - 6.2e-12 46.2 0.2 6.2e-12 46.2 0.2 7.1 2 2 1 3 3 3 1 AAA domain AAA_29 PF13555.1 KKK18327.1 - 3.6e-05 23.2 0.0 0.00011 21.6 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain Reo_sigmaC PF04582.7 KKK18327.1 - 0.00077 18.7 20.1 0.15 11.2 0.3 4.2 2 1 2 4 4 4 4 Reovirus sigma C capsid protein Spc7 PF08317.6 KKK18327.1 - 0.0016 17.1 10.1 0.0016 17.1 7.0 6.3 2 2 2 5 5 5 3 Spc7 kinetochore protein ATG16 PF08614.6 KKK18327.1 - 0.0053 16.6 2.1 0.0053 16.6 1.5 7.7 3 2 6 9 9 9 1 Autophagy protein 16 (ATG16) AAA_13 PF13166.1 KKK18327.1 - 2.1 6.6 100.6 0.011 14.2 13.6 6.2 3 2 3 6 6 6 0 AAA domain ELYS PF13934.1 KKK18328.1 - 1.2e-76 257.4 0.5 1.5e-76 257.0 0.4 1.1 1 0 0 1 1 1 1 Nuclear pore complex assembly DUF1657 PF07870.6 KKK18328.1 - 0.081 12.6 0.2 0.18 11.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1657) MobB PF03205.9 KKK18329.1 - 0.00085 19.0 0.0 0.0023 17.6 0.0 1.8 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B Clp1 PF06807.9 KKK18329.1 - 0.0027 17.5 0.0 0.16 11.7 0.0 2.5 2 0 0 2 2 2 1 Pre-mRNA cleavage complex II protein Clp1 AAA_33 PF13671.1 KKK18329.1 - 0.0031 17.3 0.0 0.02 14.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KKK18329.1 - 0.017 15.9 0.0 0.054 14.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 KKK18329.1 - 0.022 15.0 0.0 0.33 11.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 KKK18329.1 - 0.028 13.8 0.0 0.07 12.5 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_22 PF13401.1 KKK18329.1 - 0.072 13.2 0.0 0.26 11.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 KKK18329.1 - 0.11 12.7 0.0 0.59 10.3 0.0 2.2 3 0 0 3 3 3 0 RNA helicase Folliculin PF11704.3 KKK18330.1 - 9e-44 149.0 0.0 1.2e-43 148.5 0.0 1.1 1 0 0 1 1 1 1 Vesicle coat protein involved in Golgi to plasma membrane transport Prefoldin PF02996.12 KKK18331.1 - 3.3e-29 100.9 0.2 5.3e-29 100.3 0.2 1.4 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.15 KKK18331.1 - 0.00076 19.2 0.3 0.003 17.2 0.2 2.1 1 1 0 1 1 1 1 Prefoldin subunit Syntaxin-6_N PF09177.6 KKK18331.1 - 0.083 13.3 0.7 7.5 7.0 0.1 2.3 2 0 0 2 2 2 0 Syntaxin 6, N-terminal RNA_polI_A34 PF08208.6 KKK18332.1 - 5.5e-46 156.7 8.2 5.5e-46 156.7 5.7 2.6 2 0 0 2 2 2 1 DNA-directed RNA polymerase I subunit RPA34.5 GRAM PF02893.15 KKK18332.1 - 8.1e-29 98.9 0.9 1.3e-17 63.0 0.0 3.6 3 0 0 3 3 3 3 GRAM domain Glyco_transf_28 PF03033.15 KKK18332.1 - 4.6e-23 81.5 0.0 8.5e-23 80.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain PH PF00169.24 KKK18332.1 - 2.7e-15 56.4 0.1 1.7e-13 50.6 0.1 2.9 2 0 0 2 2 2 1 PH domain PH_11 PF15413.1 KKK18332.1 - 8.4e-07 29.2 0.1 3.3e-06 27.3 0.1 2.1 1 0 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.1 KKK18332.1 - 4.1e-05 23.4 0.0 8.6e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 PH domain PH_8 PF15409.1 KKK18332.1 - 8.8e-05 22.5 0.1 0.00026 20.9 0.1 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain UDPGT PF00201.13 KKK18332.1 - 0.0094 14.5 0.0 0.02 13.4 0.0 1.5 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase zf-C2H2_4 PF13894.1 KKK18352.1 - 1e-05 25.5 9.1 0.044 14.1 0.4 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.21 KKK18352.1 - 0.00066 19.8 12.6 0.048 14.0 1.1 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 KKK18352.1 - 0.0012 18.9 2.2 0.042 14.0 0.1 2.6 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.1 KKK18352.1 - 0.0078 16.4 0.4 0.0078 16.4 0.2 3.0 3 0 0 3 3 3 2 Zinc-finger double domain SprT-like PF10263.4 KKK18352.1 - 0.021 14.5 0.3 0.036 13.7 0.2 1.3 1 0 0 1 1 1 0 SprT-like family Dus PF01207.12 KKK18353.1 - 1.5e-43 148.8 0.0 4.6e-31 107.8 0.0 2.7 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) zf-CCCH PF00642.19 KKK18353.1 - 0.013 15.1 2.4 2.3 7.9 0.3 2.7 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Bap31 PF05529.7 KKK18354.1 - 2.8e-62 209.6 3.0 5e-62 208.7 2.1 1.4 1 1 0 1 1 1 1 B-cell receptor-associated protein 31-like HALZ PF02183.13 KKK18354.1 - 0.0032 17.1 0.2 0.0099 15.5 0.0 1.8 2 0 0 2 2 2 1 Homeobox associated leucine zipper DivIC PF04977.10 KKK18354.1 - 0.025 14.0 3.4 0.94 9.0 0.0 3.2 4 0 0 4 4 4 0 Septum formation initiator DUF1385 PF07136.6 KKK18354.1 - 4.6 6.2 6.7 5.9 5.8 3.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1385) RNase_T PF00929.19 KKK18364.1 - 1.7e-07 31.6 0.0 1.6e-06 28.5 0.0 2.1 1 1 0 1 1 1 1 Exonuclease Ribosomal_L22e PF01776.12 KKK18365.1 - 1.6e-50 169.8 0.5 1.9e-50 169.5 0.3 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family Meth_synt_2 PF01717.13 KKK18366.1 - 1e-19 70.7 0.0 8.9e-19 67.6 0.0 2.0 1 1 0 1 1 1 1 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 KKK18366.1 - 0.00011 21.5 0.0 0.015 14.5 0.0 2.9 3 0 0 3 3 3 2 Cobalamin-independent synthase, N-terminal domain Arf PF00025.16 KKK18367.1 - 2.3e-71 238.6 0.2 2.6e-71 238.4 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 KKK18367.1 - 3.7e-13 49.1 0.0 4.1e-13 49.0 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 KKK18367.1 - 9.4e-13 47.6 1.6 1.9e-09 36.7 0.4 2.2 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.5 KKK18367.1 - 2.7e-10 39.7 0.0 3.3e-10 39.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 KKK18367.1 - 1.1e-09 37.7 0.0 1.2e-09 37.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 KKK18367.1 - 1.6e-06 28.5 0.0 2.4e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 KKK18367.1 - 0.00015 21.6 0.1 0.00023 21.1 0.1 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KKK18367.1 - 0.0013 18.1 0.1 0.0026 17.2 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain 6PF2K PF01591.13 KKK18367.1 - 0.014 14.4 0.2 0.031 13.3 0.1 1.5 2 0 0 2 2 2 0 6-phosphofructo-2-kinase FeoB_N PF02421.13 KKK18367.1 - 0.022 14.0 0.8 0.034 13.4 0.5 1.7 1 1 0 1 1 1 0 Ferrous iron transport protein B DUF2722 PF10846.3 KKK18369.1 - 2.2e-06 26.9 0.1 2.2e-06 26.9 0.0 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF2722) Adeno_PX PF05829.7 KKK18369.1 - 0.03 13.7 0.7 4.3 6.9 0.0 2.6 2 0 0 2 2 2 0 Adenovirus late L2 mu core protein (Protein X) RabGAP-TBC PF00566.13 KKK18370.1 - 0.15 11.5 0.0 0.15 11.5 0.0 1.7 2 0 0 2 2 2 0 Rab-GTPase-TBC domain RabGAP-TBC PF00566.13 KKK18371.1 - 8.4e-08 31.9 0.0 1.1e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Methyltransf_31 PF13847.1 KKK18372.1 - 6.2e-11 42.1 0.0 1.2e-10 41.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 KKK18372.1 - 1.2e-08 34.4 0.1 2.5e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 KKK18372.1 - 6.8e-08 33.0 0.0 1.6e-07 31.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KKK18372.1 - 7.4e-08 32.7 0.0 1.6e-07 31.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KKK18372.1 - 3.6e-06 27.0 0.0 7.4e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KKK18372.1 - 1.2e-05 24.7 0.1 2.2e-05 23.9 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.1 KKK18372.1 - 7.7e-05 22.4 0.0 0.00014 21.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KKK18372.1 - 0.00021 21.6 0.0 0.00049 20.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 KKK18372.1 - 0.0015 17.3 0.0 0.0032 16.2 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_12 PF08242.7 KKK18372.1 - 0.0089 16.4 0.0 0.026 14.9 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 KKK18372.1 - 0.017 15.1 0.0 0.03 14.3 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase CMAS PF02353.15 KKK18372.1 - 0.022 13.8 0.0 0.04 12.9 0.0 1.4 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase PCMT PF01135.14 KKK18372.1 - 0.022 14.3 0.0 0.037 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) TehB PF03848.9 KKK18372.1 - 0.022 13.9 0.0 0.04 13.0 0.0 1.4 1 0 0 1 1 1 0 Tellurite resistance protein TehB MM_CoA_mutase PF01642.17 KKK18372.1 - 0.025 12.7 0.0 0.035 12.2 0.0 1.1 1 0 0 1 1 1 0 Methylmalonyl-CoA mutase PRMT5 PF05185.11 KKK18372.1 - 0.033 13.1 0.0 0.11 11.3 0.0 1.7 1 1 0 1 1 1 0 PRMT5 arginine-N-methyltransferase Met_10 PF02475.11 KKK18372.1 - 0.041 13.4 0.2 0.078 12.5 0.1 1.4 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_24 PF13578.1 KKK18372.1 - 0.1 13.4 0.0 0.26 12.1 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Mo25 PF08569.6 KKK18373.1 - 1.1e-132 442.1 0.1 1.2e-132 442.0 0.1 1.0 1 0 0 1 1 1 1 Mo25-like DLIC PF05783.6 KKK18373.1 - 0.11 11.1 0.0 0.17 10.5 0.0 1.2 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) AAA PF00004.24 KKK18374.1 - 2.7e-55 186.1 0.1 4.5e-38 130.4 0.0 2.8 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 KKK18374.1 - 6.8e-13 48.3 0.0 2.2e-12 46.7 0.0 1.9 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain CDC48_2 PF02933.12 KKK18374.1 - 4.8e-10 38.9 0.2 8.4e-09 34.9 0.0 2.6 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 AAA_22 PF13401.1 KKK18374.1 - 7.7e-10 39.0 0.2 0.00061 19.9 0.1 4.3 2 2 0 2 2 2 2 AAA domain AAA_17 PF13207.1 KKK18374.1 - 1.3e-07 32.4 0.4 0.0039 17.9 0.1 3.6 3 1 0 3 3 3 2 AAA domain AAA_2 PF07724.9 KKK18374.1 - 1.6e-07 31.4 0.2 3.3e-05 23.8 0.0 2.9 3 0 0 3 3 2 1 AAA domain (Cdc48 subfamily) AAA_14 PF13173.1 KKK18374.1 - 1.9e-07 31.0 0.1 0.03 14.2 0.0 2.7 3 0 0 3 3 2 2 AAA domain AAA_16 PF13191.1 KKK18374.1 - 3.3e-07 30.4 0.0 0.0037 17.2 0.0 2.8 2 1 0 2 2 2 2 AAA ATPase domain AAA_18 PF13238.1 KKK18374.1 - 3.9e-07 30.4 0.1 0.0063 16.8 0.0 4.0 4 0 0 4 4 4 1 AAA domain Mg_chelatase PF01078.16 KKK18374.1 - 1e-06 28.1 0.1 0.0047 16.1 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 KKK18374.1 - 1.2e-06 28.3 0.0 0.0012 18.5 0.0 3.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 KKK18374.1 - 2e-06 27.0 0.0 0.037 13.0 0.0 2.8 3 0 0 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 KKK18374.1 - 2e-06 27.4 1.7 0.024 14.3 0.0 3.7 4 0 0 4 4 4 2 Part of AAA domain AAA_33 PF13671.1 KKK18374.1 - 2.1e-06 27.6 0.0 0.048 13.5 0.0 2.9 2 1 0 2 2 2 2 AAA domain TIP49 PF06068.8 KKK18374.1 - 5.3e-06 25.4 0.0 0.022 13.4 0.0 2.6 2 0 0 2 2 2 2 TIP49 C-terminus Arch_ATPase PF01637.13 KKK18374.1 - 1.2e-05 25.2 1.2 7.4 6.1 0.0 4.2 3 1 1 4 4 4 0 Archaeal ATPase AAA_25 PF13481.1 KKK18374.1 - 2.9e-05 23.5 1.1 0.29 10.5 0.0 3.7 2 2 2 4 4 4 2 AAA domain RNA_helicase PF00910.17 KKK18374.1 - 3.5e-05 23.9 0.0 0.089 12.9 0.0 2.8 2 0 0 2 2 2 2 RNA helicase AAA_24 PF13479.1 KKK18374.1 - 5.5e-05 22.8 0.8 0.12 11.9 0.1 3.0 3 0 0 3 3 3 2 AAA domain Zeta_toxin PF06414.7 KKK18374.1 - 8.3e-05 21.7 0.0 0.3 10.1 0.0 2.9 2 0 0 2 2 2 2 Zeta toxin IstB_IS21 PF01695.12 KKK18374.1 - 0.00015 21.2 0.1 0.047 13.1 0.0 2.8 3 0 0 3 3 3 1 IstB-like ATP binding protein KaiC PF06745.8 KKK18374.1 - 0.00027 20.1 1.1 0.03 13.4 0.1 3.0 2 1 0 3 3 3 1 KaiC AAA_28 PF13521.1 KKK18374.1 - 0.0018 18.2 0.0 0.82 9.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.22 KKK18374.1 - 0.0028 17.9 0.2 0.013 15.7 0.1 2.1 2 0 0 2 2 1 1 ABC transporter Parvo_NS1 PF01057.12 KKK18374.1 - 0.0035 16.2 0.1 0.4 9.5 0.0 2.3 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 KTI12 PF08433.5 KKK18374.1 - 0.0066 15.6 0.0 1.2 8.3 0.0 2.3 2 0 0 2 2 2 1 Chromatin associated protein KTI12 AAA_11 PF13086.1 KKK18374.1 - 0.0097 15.4 0.0 1.6 8.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.21 KKK18374.1 - 0.011 15.2 0.1 0.57 9.6 0.0 2.8 3 0 0 3 3 2 0 Sigma-54 interaction domain PhoH PF02562.11 KKK18374.1 - 0.012 14.8 0.7 1.5 7.9 0.0 2.7 3 0 0 3 3 2 0 PhoH-like protein Sigma54_activ_2 PF14532.1 KKK18374.1 - 0.012 15.6 0.0 10 6.1 0.0 3.0 3 1 0 3 3 2 0 Sigma-54 interaction domain ATP-synt_ab PF00006.20 KKK18374.1 - 0.014 14.8 0.0 0.068 12.6 0.0 2.2 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain NACHT PF05729.7 KKK18374.1 - 0.018 14.7 0.0 4.8 6.8 0.0 3.1 3 1 0 3 3 2 0 NACHT domain AAA_3 PF07726.6 KKK18374.1 - 0.026 14.1 0.0 0.32 10.6 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) IPT PF01745.11 KKK18374.1 - 0.026 13.6 0.0 0.56 9.3 0.0 2.7 2 1 1 3 3 3 0 Isopentenyl transferase UPF0079 PF02367.12 KKK18374.1 - 0.046 13.3 0.1 1.3 8.6 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 NB-ARC PF00931.17 KKK18374.1 - 0.06 12.2 0.3 1.6 7.5 0.1 2.6 3 0 0 3 3 2 0 NB-ARC domain Cir_N PF10197.4 KKK18375.1 - 0.00092 19.1 7.1 0.00092 19.1 4.9 3.7 4 0 0 4 4 4 1 N-terminal domain of CBF1 interacting co-repressor CIR DIL PF01843.14 KKK18376.1 - 4.8e-19 68.1 0.5 1.2e-11 44.3 0.1 2.6 2 0 0 2 2 2 2 DIL domain Ank_2 PF12796.2 KKK18376.1 - 5.2e-19 68.3 0.0 1.5e-18 66.8 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 KKK18376.1 - 9.9e-15 53.5 0.0 1.5e-05 24.5 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 KKK18376.1 - 3.3e-13 49.3 0.0 1.6e-07 31.3 0.0 3.6 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 KKK18376.1 - 5e-12 45.9 0.1 0.00016 22.0 0.0 4.1 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KKK18376.1 - 1.1e-07 31.3 0.5 0.0047 17.0 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat RasGEF PF00617.14 KKK18377.1 - 5.5e-42 143.6 0.0 9.5e-42 142.8 0.0 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 KKK18377.1 - 1.5e-12 47.5 0.1 3.5e-12 46.3 0.1 1.6 1 0 0 1 1 1 1 RasGEF N-terminal motif KxDL PF10241.4 KKK18378.1 - 4.3e-34 116.2 0.7 5.4e-34 115.9 0.5 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein Response_reg PF00072.19 KKK18379.1 - 5.2e-22 77.9 0.1 1.2e-21 76.7 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.21 KKK18379.1 - 9.9e-21 73.5 0.0 2.3e-20 72.3 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 KKK18379.1 - 5.3e-18 64.7 0.1 1.6e-17 63.2 0.0 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.1 KKK18379.1 - 2.3e-11 43.9 0.0 8.5e-08 32.5 0.0 3.5 3 0 0 3 3 3 2 PAS domain PAS_3 PF08447.6 KKK18379.1 - 8.2e-10 38.6 4.2 0.0022 18.0 0.1 4.1 4 0 0 4 4 4 3 PAS fold PAS_4 PF08448.5 KKK18379.1 - 3.1e-06 27.1 0.1 1.3e-05 25.1 0.0 2.1 2 0 0 2 2 2 1 PAS fold PAS PF00989.19 KKK18379.1 - 0.0068 16.1 0.0 0.61 9.8 0.0 2.8 2 0 0 2 2 2 1 PAS fold MotA_ExbB PF01618.11 KKK18379.1 - 0.29 10.7 0.0 0.83 9.2 0.0 1.7 1 0 0 1 1 1 0 MotA/TolQ/ExbB proton channel family G-alpha PF00503.15 KKK18380.1 - 3.1e-114 381.6 0.1 3.8e-114 381.3 0.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 KKK18380.1 - 4.4e-14 52.1 0.5 1.9e-09 36.9 0.0 2.8 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KKK18380.1 - 3.2e-07 29.7 0.1 0.0023 17.1 0.1 2.2 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Miro PF08477.8 KKK18380.1 - 0.0076 16.7 0.0 0.48 10.9 0.0 2.7 2 1 0 2 2 2 1 Miro-like protein MMR_HSR1 PF01926.18 KKK18380.1 - 0.021 14.7 0.0 5.5 6.9 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_29 PF13555.1 KKK18380.1 - 0.037 13.5 0.0 0.079 12.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain GTP_EFTU PF00009.22 KKK18380.1 - 0.065 12.6 0.0 4.5 6.6 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Peptidase_M13_N PF05649.8 KKK18381.1 - 2.6e-90 303.2 0.0 3.2e-90 302.9 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.16 KKK18381.1 - 1.1e-43 148.8 0.0 9.5e-32 109.8 0.0 2.3 1 1 1 2 2 2 2 Peptidase family M13 ATP-synt_C PF00137.16 KKK18382.1 - 4.5e-32 109.7 29.8 7.9e-18 64.1 8.7 2.0 2 0 0 2 2 2 2 ATP synthase subunit C Flavi_NS4A PF01350.12 KKK18382.1 - 0.14 11.7 3.9 0.055 13.0 0.7 1.7 2 0 0 2 2 2 0 Flavivirus non-structural protein NS4A DUF1713 PF08213.6 KKK18383.1 - 1.1e-12 47.3 20.7 2.1e-12 46.4 14.4 1.5 1 0 0 1 1 1 1 Mitochondrial domain of unknown function (DUF1713) Pet20 PF08692.5 KKK18383.1 - 0.0011 18.8 0.0 0.0038 17.1 0.0 1.9 2 0 0 2 2 2 1 Mitochondrial protein Pet20 Pmp3 PF01679.12 KKK18384.1 - 4.6e-26 90.2 6.0 5e-26 90.1 4.2 1.0 1 0 0 1 1 1 1 Proteolipid membrane potential modulator DctM PF06808.7 KKK18384.1 - 0.055 12.0 0.1 0.06 11.9 0.1 1.0 1 0 0 1 1 1 0 DctM-like transporters Hydrolase_6 PF13344.1 KKK18386.1 - 7.8e-22 77.0 0.0 1.6e-21 76.1 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KKK18386.1 - 3.2e-11 42.7 0.0 1e-09 37.9 0.0 3.0 4 0 0 4 4 4 1 HAD-hyrolase-like HAD_2 PF13419.1 KKK18386.1 - 0.053 13.7 0.0 12 6.1 0.0 2.5 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KKK18386.1 - 0.1 12.9 0.0 0.86 9.9 0.0 2.2 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase CFEM PF05730.6 KKK18387.1 - 0.026 14.3 4.1 0.049 13.4 2.8 1.4 1 0 0 1 1 1 0 CFEM domain Asp PF00026.18 KKK18388.1 - 3.1e-08 33.2 1.5 4.9e-08 32.5 1.1 1.3 1 0 0 1 1 1 1 Eukaryotic aspartyl protease SKG6 PF08693.5 KKK18388.1 - 0.023 13.9 2.0 0.073 12.3 1.4 1.8 1 0 0 1 1 1 0 Transmembrane alpha-helix domain VSP PF03302.8 KKK18388.1 - 0.031 12.8 0.4 0.031 12.8 0.3 1.9 2 0 0 2 2 2 0 Giardia variant-specific surface protein DUF2029 PF09594.5 KKK18388.1 - 0.05 13.0 0.1 0.098 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2029) Vpu PF00558.14 KKK18388.1 - 0.11 12.1 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Vpu protein Herpes_gE PF02480.11 KKK18388.1 - 0.2 9.8 0.0 0.35 9.0 0.0 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF676 PF05057.9 KKK18389.1 - 6.2e-48 162.9 0.0 9.1e-48 162.4 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.2 KKK18389.1 - 4.3e-07 30.0 0.1 8.5e-07 29.0 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KKK18389.1 - 1.4e-05 24.9 0.0 2.4e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 KKK18389.1 - 2.2e-05 24.1 0.0 3.6e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Lipase_3 PF01764.20 KKK18389.1 - 0.0051 16.4 0.0 0.01 15.4 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_1 PF00561.15 KKK18389.1 - 0.024 14.1 0.0 0.058 12.9 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold LCAT PF02450.10 KKK18389.1 - 0.063 12.2 0.0 0.1 11.5 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DUF915 PF06028.6 KKK18389.1 - 0.099 11.7 0.0 4.1 6.4 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) FA_hydroxylase PF04116.8 KKK18395.1 - 1.4e-15 57.7 18.2 1.4e-15 57.7 12.6 2.1 3 0 0 3 3 3 1 Fatty acid hydroxylase superfamily Ras PF00071.17 KKK18396.1 - 2e-65 219.1 0.1 2.3e-65 218.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KKK18396.1 - 7.6e-19 68.3 0.0 1e-18 67.9 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KKK18396.1 - 7.1e-14 51.4 0.1 9.2e-14 51.0 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KKK18396.1 - 7.7e-07 28.7 0.0 1.3e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 KKK18396.1 - 2.1e-06 27.0 0.0 2.5e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KKK18396.1 - 0.0046 16.8 0.0 0.0074 16.2 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KKK18396.1 - 0.015 14.5 0.0 0.073 12.3 0.0 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA PF00004.24 KKK18396.1 - 0.025 14.7 0.0 5.8 7.1 0.0 2.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) SRPRB PF09439.5 KKK18396.1 - 0.026 13.7 0.0 0.031 13.4 0.0 1.1 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 KKK18396.1 - 0.11 12.6 0.0 0.26 11.4 0.0 1.9 1 1 1 2 2 2 0 AAA domain AAA_29 PF13555.1 KKK18396.1 - 0.13 11.8 0.7 0.29 10.6 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain NCA2 PF08637.5 KKK18397.1 - 1.7e-73 247.0 0.0 3.4e-73 246.0 0.0 1.5 2 0 0 2 2 2 1 ATP synthase regulation protein NCA2 RRM_1 PF00076.17 KKK18398.1 - 1.9e-15 56.2 0.0 3.2e-15 55.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KKK18398.1 - 7.6e-10 38.6 0.0 1.2e-09 38.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KKK18398.1 - 2.9e-08 33.4 0.0 4.8e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KKK18398.1 - 0.0019 18.0 0.0 0.0032 17.2 0.0 1.3 1 0 0 1 1 1 1 RNA binding motif DUF1777 PF08648.7 KKK18398.1 - 2.5 7.8 24.4 3.2 7.4 16.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) AAA PF00004.24 KKK18399.1 - 3.3e-62 208.5 0.0 8.2e-42 142.5 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KKK18399.1 - 4.4e-10 39.8 1.0 0.0024 17.9 0.0 3.8 2 2 0 2 2 2 2 AAA ATPase domain AAA_5 PF07728.9 KKK18399.1 - 8e-07 28.8 1.2 0.0028 17.3 0.1 3.3 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KKK18399.1 - 2.4e-06 27.7 5.1 0.53 10.4 0.1 5.0 4 2 0 5 5 4 2 AAA domain AAA_28 PF13521.1 KKK18399.1 - 7.2e-06 26.0 0.0 0.043 13.7 0.0 2.8 2 0 0 2 2 2 2 AAA domain Arch_ATPase PF01637.13 KKK18399.1 - 4.9e-05 23.1 0.1 0.12 12.0 0.0 3.3 2 1 1 4 4 4 2 Archaeal ATPase AAA_14 PF13173.1 KKK18399.1 - 5.8e-05 23.0 0.0 0.13 12.1 0.0 3.1 3 0 0 3 3 3 2 AAA domain RNA_helicase PF00910.17 KKK18399.1 - 0.00011 22.3 0.0 0.42 10.8 0.0 2.8 2 1 0 2 2 2 2 RNA helicase TIP49 PF06068.8 KKK18399.1 - 0.00013 20.8 0.1 0.0073 15.0 0.0 2.4 2 0 0 2 2 2 1 TIP49 C-terminus Rad17 PF03215.10 KKK18399.1 - 0.00025 19.8 0.0 0.00073 18.3 0.0 1.7 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_25 PF13481.1 KKK18399.1 - 0.00035 20.0 5.5 1.4 8.2 0.0 4.2 2 2 0 3 3 3 1 AAA domain RuvB_N PF05496.7 KKK18399.1 - 0.00047 19.2 0.0 0.018 14.1 0.0 3.0 2 1 1 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 KKK18399.1 - 0.00048 20.9 0.5 0.57 11.0 0.0 3.0 2 2 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KKK18399.1 - 0.0006 19.5 0.3 0.79 9.5 0.0 3.9 4 0 0 4 4 4 1 Part of AAA domain AAA_2 PF07724.9 KKK18399.1 - 0.00065 19.6 0.0 0.0025 17.7 0.0 2.1 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_24 PF13479.1 KKK18399.1 - 0.0015 18.1 1.1 0.069 12.7 0.1 2.5 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 KKK18399.1 - 0.0021 17.5 0.0 1.3 8.4 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein DUF815 PF05673.8 KKK18399.1 - 0.0021 17.0 0.0 1.5 7.6 0.0 2.6 3 0 0 3 3 3 2 Protein of unknown function (DUF815) NACHT PF05729.7 KKK18399.1 - 0.027 14.1 0.6 6.5 6.3 0.1 3.8 2 2 1 3 3 3 0 NACHT domain Sigma54_activ_2 PF14532.1 KKK18399.1 - 0.059 13.4 0.0 1.3 9.0 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_29 PF13555.1 KKK18399.1 - 0.077 12.5 0.1 0.34 10.4 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain Mg_chelatase PF01078.16 KKK18399.1 - 0.094 11.8 0.5 2.4 7.2 0.0 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI DUF258 PF03193.11 KKK18399.1 - 0.13 11.4 0.0 0.61 9.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Swi3 PF07962.7 KKK18400.1 - 7.7e-32 108.7 0.6 1.4e-31 107.9 0.2 1.6 2 0 0 2 2 2 1 Replication Fork Protection Component Swi3 Pox_Ag35 PF03286.9 KKK18400.1 - 2.1 7.8 7.2 0.7 9.3 3.0 1.8 2 0 0 2 2 2 0 Pox virus Ag35 surface protein NADH_u_ox_C PF12853.2 KKK18401.1 - 1.5e-33 114.3 0.1 2.2e-33 113.8 0.1 1.2 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit NADH-u_ox-rdase PF10785.4 KKK18401.1 - 2.3e-32 111.0 0.3 6.7e-32 109.5 0.2 1.8 1 1 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit dCMP_cyt_deam_1 PF00383.17 KKK18402.1 - 4.6e-25 87.2 0.0 5.9e-25 86.8 0.0 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 KKK18402.1 - 0.1 12.4 0.9 0.43 10.4 0.6 1.9 1 1 0 1 1 1 0 Bd3614-like deaminase PI3_PI4_kinase PF00454.22 KKK18403.1 - 3.2e-54 183.8 0.2 8.3e-54 182.5 0.1 1.7 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.18 KKK18403.1 - 3.9e-50 170.8 3.1 9.3e-50 169.5 2.2 1.7 1 0 0 1 1 1 1 FAT domain UME PF08064.8 KKK18403.1 - 2.7e-33 114.1 0.2 1.6e-32 111.6 0.1 2.5 1 0 0 1 1 1 1 UME (NUC010) domain FATC PF02260.15 KKK18403.1 - 4.3e-14 51.6 0.0 1.5e-13 49.9 0.0 2.0 1 0 0 1 1 1 1 FATC domain TPR_11 PF13414.1 KKK18403.1 - 6.1e-05 22.5 1.2 0.62 9.7 0.0 3.7 3 0 0 3 3 3 1 TPR repeat TPR_17 PF13431.1 KKK18403.1 - 0.012 15.8 1.4 4.6 7.7 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 KKK18403.1 - 0.013 16.0 3.4 8.1 7.3 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.1 KKK18403.1 - 0.026 14.3 0.7 20 5.3 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 KKK18403.1 - 0.088 13.5 0.3 2.9 8.6 0.1 3.0 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.1 KKK18403.1 - 0.11 12.8 0.4 25 5.2 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Metallophos_2 PF12850.2 KKK18413.1 - 1e-14 54.6 0.0 1.3e-14 54.3 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Aminotran_5 PF00266.14 KKK18414.1 - 7.2e-28 97.3 0.0 9.3e-28 97.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V B12-binding PF02310.14 KKK18414.1 - 0.00028 20.7 0.2 0.00075 19.3 0.0 1.8 2 0 0 2 2 2 1 B12 binding domain DDE_Tnp_1_4 PF13701.1 KKK18414.1 - 0.19 9.8 0.0 0.29 9.2 0.0 1.2 1 0 0 1 1 1 0 Transposase DDE domain group 1 Ribosomal_L17 PF01196.14 KKK18416.1 - 5e-34 116.7 0.0 7.9e-34 116.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L17 SUZ PF12752.2 KKK18417.1 - 8.6e-20 71.0 2.9 8.6e-20 71.0 2.0 2.4 2 0 0 2 2 2 1 SUZ domain R3H PF01424.17 KKK18417.1 - 1.3e-07 31.2 0.1 2.9e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 R3H domain zf-CCHC_3 PF13917.1 KKK18418.1 - 0.014 15.0 2.2 0.016 14.9 0.2 2.1 2 0 0 2 2 2 0 Zinc knuckle NIF PF03031.13 KKK18419.1 - 7.6e-54 181.6 0.0 1.4e-53 180.8 0.0 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Macoilin PF09726.4 KKK18419.1 - 0.12 10.6 3.4 0.18 10.0 2.3 1.3 1 0 0 1 1 1 0 Transmembrane protein IF-2B PF01008.12 KKK18420.1 - 9.2e-62 208.5 0.3 1.2e-59 201.6 0.2 2.3 1 1 0 1 1 1 1 Initiation factor 2 subunit family Ribosom_S12_S23 PF00164.20 KKK18421.1 - 1.2e-40 137.6 0.4 1.5e-40 137.4 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 PPR_2 PF13041.1 KKK18423.1 - 6.7e-11 41.9 4.2 0.00065 19.6 0.1 4.4 4 1 1 5 5 5 3 PPR repeat family PPR_3 PF13812.1 KKK18423.1 - 2.8e-09 36.5 5.2 0.32 11.3 0.1 7.2 9 0 0 9 9 9 3 Pentatricopeptide repeat domain PPR PF01535.15 KKK18423.1 - 0.0024 17.7 0.2 0.84 9.7 0.0 4.0 4 0 0 4 4 4 1 PPR repeat ATP13 PF12921.2 KKK18423.1 - 0.065 12.5 0.3 0.21 10.9 0.1 1.9 2 0 0 2 2 2 0 Mitochondrial ATPase expression cwf18 PF08315.7 KKK18424.1 - 2.8e-44 150.7 6.2 2.8e-44 150.7 4.3 1.4 2 0 0 2 2 2 1 cwf18 pre-mRNA splicing factor PP2C PF00481.16 KKK18425.1 - 6.2e-76 255.1 0.0 8.8e-76 254.6 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 KKK18425.1 - 0.0011 18.4 0.0 0.0023 17.3 0.0 1.6 1 0 0 1 1 1 1 Protein phosphatase 2C CTP_transf_2 PF01467.21 KKK18426.1 - 6.4e-22 78.2 0.0 1e-21 77.6 0.0 1.3 1 0 0 1 1 1 1 Cytidylyltransferase EamA PF00892.15 KKK18427.1 - 7.8e-16 58.2 20.4 1.2e-09 38.3 0.8 3.3 3 0 0 3 3 3 3 EamA-like transporter family EmrE PF13536.1 KKK18427.1 - 0.00037 20.6 3.3 0.00037 20.6 2.3 4.1 3 1 1 4 4 4 2 Multidrug resistance efflux transporter DUF1469 PF07332.6 KKK18427.1 - 1.2 8.8 0.0 1.2 8.8 0.0 3.1 4 0 0 4 4 4 0 Protein of unknown function (DUF1469) SR-25 PF10500.4 KKK18427.1 - 4.7 6.6 10.6 8.3 5.8 7.3 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF1253 PF06862.7 KKK18428.1 - 6.1e-137 456.6 0.0 1.8e-90 303.5 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF1253) Nop14 PF04147.7 KKK18428.1 - 0.44 8.4 19.6 0.71 7.7 13.6 1.3 1 0 0 1 1 1 0 Nop14-like family JAB PF01398.16 KKK18429.1 - 1.3e-16 60.2 0.0 2.3e-16 59.5 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 KKK18429.1 - 4e-16 59.1 0.0 7.4e-16 58.2 0.0 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function UPF0172 PF03665.8 KKK18429.1 - 0.072 12.5 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0172) TFIID-18kDa PF02269.11 KKK18430.1 - 5.5e-23 80.5 0.0 1.3e-22 79.4 0.0 1.6 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Histone PF00125.19 KKK18430.1 - 0.0078 16.3 0.0 0.017 15.1 0.0 1.6 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 KKK18430.1 - 0.033 14.3 0.0 0.065 13.4 0.0 1.4 1 0 0 1 1 1 0 Kinetochore component CENP-S TAF PF02969.12 KKK18430.1 - 0.035 14.0 0.0 0.071 13.0 0.0 1.5 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) Bromo_TP PF07524.8 KKK18430.1 - 0.15 11.7 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated CD99L2 PF12301.3 KKK18430.1 - 4.4 6.9 16.0 2.4 7.8 3.4 2.2 2 0 0 2 2 2 0 CD99 antigen like protein 2 HECT PF00632.20 KKK18431.1 - 1e-92 310.7 0.0 1.5e-92 310.1 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.21 KKK18431.1 - 7.5e-33 112.0 20.3 7.2e-11 41.7 3.0 3.9 3 0 0 3 3 3 3 WW domain RRM_1 PF00076.17 KKK18431.1 - 1.3e-15 56.7 0.0 3.6e-15 55.3 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) C2 PF00168.25 KKK18431.1 - 4.1e-15 55.3 0.0 1e-14 54.1 0.0 1.7 1 0 0 1 1 1 1 C2 domain RRM_6 PF14259.1 KKK18431.1 - 2.2e-13 49.9 0.0 5.7e-13 48.6 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KKK18431.1 - 7.5e-05 22.5 0.0 0.00017 21.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) IncA PF04156.9 KKK18431.1 - 0.35 10.4 3.1 0.66 9.5 2.2 1.4 1 0 0 1 1 1 0 IncA protein APG6 PF04111.7 KKK18431.1 - 0.48 9.4 3.0 0.76 8.7 2.1 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 Aminotran_1_2 PF00155.16 KKK18433.1 - 1.6e-72 244.4 0.0 1.8e-72 244.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II RRM_6 PF14259.1 KKK18434.1 - 0.019 14.9 0.0 0.043 13.7 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) TYW3 PF02676.9 KKK18435.1 - 4.8e-76 254.4 0.0 6.1e-76 254.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase TYW3 DUF2461 PF09365.5 KKK18436.1 - 1.4e-77 259.8 0.0 2e-77 259.3 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein (DUF2461) Lyase_1 PF00206.15 KKK18437.1 - 3.7e-115 384.3 0.0 4.9e-115 384.0 0.0 1.2 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.4 KKK18437.1 - 3.9e-22 78.0 0.0 1.1e-21 76.6 0.0 1.8 1 0 0 1 1 1 1 Fumarase C C-terminus Abhydrolase_3 PF07859.8 KKK18438.1 - 3e-10 40.0 0.2 5.9e-05 22.7 0.0 2.0 1 1 1 2 2 2 2 alpha/beta hydrolase fold Pectate_lyase_3 PF12708.2 KKK18438.1 - 0.12 12.4 0.0 0.13 12.3 0.0 1.1 1 0 0 1 1 1 0 Pectate lyase superfamily protein ARPC4 PF05856.7 KKK18439.1 - 7e-76 253.3 4.1 7.8e-76 253.2 2.8 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) UCH PF00443.24 KKK18440.1 - 1.7e-54 184.7 0.1 2.2e-54 184.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KKK18440.1 - 1.5e-14 54.1 2.7 1.4e-13 50.9 1.9 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.18 KKK18440.1 - 2.8e-11 42.6 0.1 1.2e-10 40.6 0.0 2.1 2 0 0 2 2 2 1 Ubiquitin family 4HBT PF03061.17 KKK18441.1 - 0.0024 17.9 0.0 0.0038 17.3 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily TRI12 PF06609.8 KKK18442.1 - 1.1e-37 129.5 25.0 1.4e-37 129.2 17.3 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 KKK18442.1 - 3.8e-16 58.7 56.6 3.8e-16 58.7 39.2 3.0 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KKK18442.1 - 5.5e-08 31.8 15.4 5.5e-08 31.8 10.7 3.2 2 1 1 3 3 3 2 Sugar (and other) transporter Cation_ATPase_C PF00689.16 KKK18442.1 - 0.00019 21.0 6.2 0.00019 21.0 4.3 2.6 2 1 0 2 2 2 1 Cation transporting ATPase, C-terminus WD40 PF00400.27 KKK18443.1 - 2.6e-12 46.1 17.1 0.00011 21.8 0.0 5.8 6 0 0 6 6 6 3 WD domain, G-beta repeat RWD PF05773.17 KKK18443.1 - 0.00025 20.8 0.0 0.00066 19.5 0.0 1.6 1 0 0 1 1 1 1 RWD domain zf-C3HC4_2 PF13923.1 KKK18443.1 - 3.9 7.5 18.2 0.4 10.7 9.3 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Ribosomal_L24e PF01246.15 KKK18444.1 - 2.2e-31 107.4 0.4 2.2e-31 107.4 0.3 2.1 2 0 0 2 2 2 1 Ribosomal protein L24e Ribosomal_S30 PF04758.9 KKK18445.1 - 7.4e-28 96.0 5.9 8.5e-28 95.8 4.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 Acetyltransf_7 PF13508.1 KKK18446.1 - 1e-11 44.7 0.2 2.2e-11 43.7 0.2 1.5 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KKK18446.1 - 1e-09 38.3 0.1 1.6e-09 37.6 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 KKK18446.1 - 0.0041 17.2 0.0 0.0053 16.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 KKK18446.1 - 0.006 16.7 0.0 0.0073 16.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KKK18446.1 - 0.08 12.8 0.0 0.1 12.4 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Zn_clus PF00172.13 KKK18447.1 - 0.0027 17.5 7.7 0.0058 16.5 5.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BRAP2 PF07576.7 KKK18448.1 - 9.4e-26 89.5 0.0 1.9e-25 88.5 0.0 1.4 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.14 KKK18448.1 - 4.2e-20 71.6 2.9 1.3e-19 70.0 2.0 1.9 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.1 KKK18448.1 - 3.6e-09 36.2 9.9 3.6e-09 36.2 6.9 2.5 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 KKK18448.1 - 0.00019 21.1 7.7 0.00019 21.1 5.4 2.5 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KKK18448.1 - 0.00099 18.7 8.8 0.00099 18.7 6.1 2.0 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KKK18448.1 - 0.001 19.0 9.7 0.001 19.0 6.7 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KKK18448.1 - 0.0015 18.1 6.1 0.0015 18.1 4.3 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KKK18448.1 - 0.0016 18.1 4.7 0.0059 16.2 1.8 2.6 1 1 1 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.2 KKK18448.1 - 0.002 18.2 5.5 0.002 18.2 3.8 2.4 2 0 0 2 2 2 1 RING-H2 zinc finger zf-RING_6 PF14835.1 KKK18448.1 - 0.013 15.2 3.5 0.013 15.2 2.4 2.2 2 0 0 2 2 1 0 zf-RING of BARD1-type protein TPR_MLP1_2 PF07926.7 KKK18448.1 - 0.031 13.9 10.6 0.056 13.1 7.3 1.3 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Shugoshin_N PF07558.6 KKK18448.1 - 0.32 10.7 2.0 0.72 9.6 1.4 1.6 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region CCDC155 PF14662.1 KKK18448.1 - 0.41 10.2 9.0 0.69 9.4 6.2 1.3 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 DUF2937 PF11157.3 KKK18448.1 - 0.87 8.8 3.8 0.96 8.7 0.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2937) DUF904 PF06005.7 KKK18448.1 - 1.1 9.5 4.7 0.49 10.7 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF904) Baculo_RING PF05883.6 KKK18448.1 - 1.2 9.0 3.7 0.86 9.4 1.3 1.7 2 0 0 2 2 1 0 Baculovirus U-box/Ring-like domain APG6 PF04111.7 KKK18448.1 - 1.2 8.0 10.2 1.9 7.4 7.1 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF4200 PF13863.1 KKK18448.1 - 1.3 8.9 13.8 0.58 10.1 3.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) zf-Apc11 PF12861.2 KKK18448.1 - 1.6 8.6 12.8 0.027 14.3 3.6 1.9 2 0 0 2 2 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Exonuc_VII_L PF02601.10 KKK18448.1 - 2.5 7.2 6.8 2.1 7.4 3.7 1.5 2 0 0 2 2 2 0 Exonuclease VII, large subunit V_ATPase_I PF01496.14 KKK18448.1 - 3.2 5.4 4.5 4.4 5.0 3.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Prok-RING_4 PF14447.1 KKK18448.1 - 4.1 7.0 8.7 27 4.4 4.2 2.5 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 Uso1_p115_C PF04871.8 KKK18448.1 - 8.7 6.2 10.8 0.68 9.8 1.7 2.2 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Methyltransf_23 PF13489.1 KKK18449.1 - 5e-18 65.3 0.0 8.5e-18 64.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KKK18449.1 - 2.3e-11 44.0 0.0 1e-10 41.9 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KKK18449.1 - 4.1e-10 40.0 0.0 9.4e-10 38.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KKK18449.1 - 5.8e-09 36.5 0.0 9.1e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KKK18449.1 - 6.9e-09 35.4 0.0 8.2e-08 31.9 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KKK18449.1 - 0.00011 22.1 0.0 0.00023 21.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KKK18449.1 - 0.00045 20.5 0.0 0.00083 19.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.1 KKK18449.1 - 0.08 13.7 0.0 0.17 12.7 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Prp18 PF02840.10 KKK18449.1 - 0.095 12.5 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Prp18 domain NodS PF05401.6 KKK18449.1 - 0.13 11.6 0.0 12 5.1 0.0 2.3 2 0 0 2 2 2 0 Nodulation protein S (NodS) TRI12 PF06609.8 KKK18450.1 - 1.2e-28 99.6 27.6 1.6e-28 99.2 19.2 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 KKK18450.1 - 1.4e-21 76.5 46.2 5.1e-21 74.7 29.8 2.4 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KKK18450.1 - 9.1e-08 31.1 7.4 9.1e-08 31.1 5.1 3.6 3 1 1 4 4 4 1 Sugar (and other) transporter Abhydrolase_3 PF07859.8 KKK18451.1 - 7.3e-27 94.3 0.0 1e-26 93.8 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 KKK18451.1 - 5.1e-15 54.9 0.0 1.8e-14 53.1 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 KKK18451.1 - 6.3e-07 29.2 0.0 9e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KKK18451.1 - 0.00063 19.0 0.0 0.0012 18.1 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family COesterase PF00135.23 KKK18451.1 - 0.0029 16.3 0.0 0.0045 15.7 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family UPF0565 PF10561.4 KKK18451.1 - 0.042 12.7 0.0 0.055 12.3 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 Zn_clus PF00172.13 KKK18461.1 - 9e-11 41.5 8.5 1.8e-10 40.5 5.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KKK18461.1 - 6.7e-09 35.0 0.0 1.3e-08 34.0 0.0 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Fungal_trans_2 PF11951.3 KKK18461.1 - 0.022 13.3 0.0 1.1 7.7 0.0 2.5 2 0 0 2 2 2 0 Fungal specific transcription factor domain Glyco_hydro_98C PF08307.6 KKK18461.1 - 0.33 10.2 0.0 0.51 9.5 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 98 C-terminal domain DUF3455 PF11937.3 KKK18462.1 - 1.1e-43 149.3 0.1 1.3e-43 149.0 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) DUF1455 PF07306.6 KKK18465.1 - 0.019 15.0 0.0 0.039 14.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1455) Chlorosome_CsmC PF11098.3 KKK18465.1 - 0.16 11.6 2.2 0.38 10.4 1.5 1.6 1 0 0 1 1 1 0 Chlorosome envelope protein C Myb_DNA-bind_6 PF13921.1 KKK18475.1 - 3.5e-16 59.0 0.1 4.5e-07 29.8 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 KKK18475.1 - 2e-11 43.7 0.4 3.6e-05 23.7 0.0 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Phosphoprotein PF00922.12 KKK18475.1 - 0.4 9.8 4.3 0.91 8.6 3.0 1.6 1 0 0 1 1 1 0 Vesiculovirus phosphoprotein Zn_clus PF00172.13 KKK18476.1 - 8.7e-06 25.5 8.2 1.6e-05 24.6 5.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PX PF00787.19 KKK18477.1 - 9.7e-27 93.0 0.2 1.2e-26 92.7 0.1 1.1 1 0 0 1 1 1 1 PX domain FAM91_N PF14647.1 KKK18477.1 - 0.1 11.6 0.0 0.12 11.3 0.0 1.1 1 0 0 1 1 1 0 FAM91 N-terminus RRM_6 PF14259.1 KKK18478.1 - 3.3e-06 26.9 0.0 5.9e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KKK18478.1 - 0.0011 18.5 0.0 0.0021 17.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1793 PF08760.6 KKK18479.1 - 3.3e-66 222.3 0.5 8.4e-66 221.0 0.3 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1793) Annexin PF00191.15 KKK18480.1 - 1.6e-15 56.7 4.2 1e-05 25.3 0.1 4.4 4 0 0 4 4 4 4 Annexin PAT1 PF09770.4 KKK18480.1 - 0.024 12.9 16.3 0.035 12.3 11.3 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Pkinase PF00069.20 KKK18481.1 - 9.2e-24 83.9 0.0 2.8e-23 82.3 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK18481.1 - 1.8e-09 37.0 0.0 0.00062 18.9 0.0 3.3 4 0 0 4 4 4 2 Protein tyrosine kinase APH PF01636.18 KKK18481.1 - 0.035 13.8 0.1 0.56 9.8 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family MIP-T3 PF10243.4 KKK18482.1 - 0.034 12.6 38.7 0.044 12.2 26.8 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF605 PF04652.11 KKK18482.1 - 0.096 12.0 18.3 0.13 11.5 12.7 1.1 1 0 0 1 1 1 0 Vta1 like Macoilin PF09726.4 KKK18482.1 - 0.94 7.6 14.1 0.99 7.6 9.8 1.1 1 0 0 1 1 1 0 Transmembrane protein Septin PF00735.13 KKK18483.1 - 4.1e-33 114.6 0.0 3.3e-13 49.2 0.0 3.1 3 0 0 3 3 3 3 Septin FtsK_SpoIIIE PF01580.13 KKK18483.1 - 0.00097 18.6 0.0 0.0017 17.8 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family Dynamin_N PF00350.18 KKK18483.1 - 0.0073 16.1 1.2 0.022 14.6 0.0 2.4 3 1 0 3 3 3 1 Dynamin family Miro PF08477.8 KKK18483.1 - 0.012 16.1 0.0 0.033 14.6 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein MMR_HSR1 PF01926.18 KKK18483.1 - 0.018 14.9 0.0 0.039 13.9 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_16 PF13191.1 KKK18483.1 - 0.066 13.1 0.0 0.27 11.1 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain DOPA_dioxygen PF08883.6 KKK18484.1 - 3.9e-30 103.9 0.0 6.3e-30 103.3 0.0 1.3 1 0 0 1 1 1 1 Dopa 4,5-dioxygenase family DUF946 PF06101.6 KKK18484.1 - 4.7e-11 41.3 0.9 4.7e-11 41.3 0.6 1.6 2 0 0 2 2 2 1 Plant protein of unknown function (DUF946) NPP1 PF05630.6 KKK18484.1 - 0.021 14.5 1.3 0.036 13.8 0.9 1.3 1 0 0 1 1 1 0 Necrosis inducing protein (NPP1) Ribosomal_L21e PF01157.13 KKK18485.1 - 8.7e-39 131.3 5.6 8.7e-39 131.3 3.9 1.7 2 0 0 2 2 2 1 Ribosomal protein L21e 3H PF02829.9 KKK18485.1 - 0.029 14.3 1.3 0.029 14.3 0.2 1.5 2 0 0 2 2 2 0 3H domain Surface_Ag_2 PF01617.12 KKK18485.1 - 0.063 12.4 0.3 0.076 12.2 0.2 1.2 1 0 0 1 1 1 0 Surface antigen Endonuc_Holl PF10107.4 KKK18485.1 - 0.066 12.9 0.1 0.093 12.4 0.1 1.2 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase WD40 PF00400.27 KKK18486.1 - 3.3e-25 86.9 13.4 1.9e-07 30.6 0.2 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 KKK18486.1 - 3.5e-05 22.2 0.2 0.16 10.2 0.0 3.8 3 1 1 4 4 4 3 Cytochrome D1 heme domain PQQ_3 PF13570.1 KKK18486.1 - 0.0001 22.4 1.6 0.63 10.3 0.0 3.5 3 0 0 3 3 3 2 PQQ-like domain BBS2_Mid PF14783.1 KKK18486.1 - 0.091 12.5 0.0 22 4.8 0.0 3.5 4 0 0 4 4 4 0 Ciliary BBSome complex subunit 2, middle region DUF3584 PF12128.3 KKK18487.1 - 8.6e-05 20.1 9.4 0.00013 19.5 6.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) BLOC1_2 PF10046.4 KKK18487.1 - 0.0029 17.7 2.2 0.0029 17.7 1.5 3.0 3 1 0 3 3 3 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Baculo_PEP_C PF04513.7 KKK18487.1 - 0.006 16.4 7.5 0.0098 15.7 0.7 2.7 3 0 0 3 3 3 1 Baculovirus polyhedron envelope protein, PEP, C terminus Prefoldin PF02996.12 KKK18487.1 - 0.021 14.4 15.2 0.024 14.3 1.7 4.2 2 1 2 4 4 4 0 Prefoldin subunit Bap31 PF05529.7 KKK18487.1 - 0.089 12.2 9.0 0.19 11.1 0.0 3.1 3 1 0 3 3 3 0 B-cell receptor-associated protein 31-like CRIC_ras_sig PF10534.4 KKK18487.1 - 0.1 12.6 2.2 0.12 12.4 0.7 1.8 2 0 0 2 2 1 0 Connector enhancer of kinase suppressor of ras FlaC_arch PF05377.6 KKK18487.1 - 0.14 12.0 5.8 4.8 7.1 0.6 3.4 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) NPV_P10 PF05531.7 KKK18487.1 - 0.17 12.1 4.2 9.1 6.6 0.3 3.5 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein IncA PF04156.9 KKK18487.1 - 0.24 10.9 23.1 0.76 9.3 4.0 3.2 2 1 1 3 3 3 0 IncA protein Prefoldin_2 PF01920.15 KKK18487.1 - 0.27 11.0 21.0 0.16 11.7 2.6 4.1 2 1 1 3 3 3 0 Prefoldin subunit Reo_sigmaC PF04582.7 KKK18487.1 - 0.29 10.2 4.2 0.67 9.0 1.5 2.0 1 1 1 2 2 2 0 Reovirus sigma C capsid protein ALMT PF11744.3 KKK18487.1 - 0.29 9.7 1.8 0.42 9.2 1.3 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter DASH_Dam1 PF08653.5 KKK18487.1 - 0.54 10.0 1.8 2 8.2 0.1 2.6 3 1 0 3 3 3 0 DASH complex subunit Dam1 CENP-F_leu_zip PF10473.4 KKK18487.1 - 0.95 9.3 19.4 4.9 7.0 2.9 3.4 3 1 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4407 PF14362.1 KKK18487.1 - 1.1 8.1 11.3 2.1 7.1 7.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Fib_alpha PF08702.5 KKK18487.1 - 2.7 8.1 8.4 2 8.5 2.1 2.8 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family DUF3552 PF12072.3 KKK18487.1 - 3 7.0 19.5 5.3 6.1 4.5 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) DUF972 PF06156.8 KKK18487.1 - 3 8.2 14.6 4.6 7.6 0.7 3.5 3 1 0 3 3 3 0 Protein of unknown function (DUF972) NAM-associated PF14303.1 KKK18487.1 - 4.8 7.4 9.0 1.1 9.5 0.1 2.5 2 1 0 2 2 2 0 No apical meristem-associated C-terminal domain COG2 PF06148.6 KKK18487.1 - 5.1 6.9 15.5 0.45 10.3 2.0 2.8 2 1 0 3 3 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Tropomyosin_1 PF12718.2 KKK18487.1 - 5.8 6.7 22.4 2.8 7.7 12.9 2.2 2 0 0 2 2 2 0 Tropomyosin like ISG65-75 PF11727.3 KKK18487.1 - 7.6 5.5 8.9 1.5 7.8 1.6 2.1 2 0 0 2 2 2 0 Invariant surface glycoprotein Fez1 PF06818.10 KKK18487.1 - 9 6.2 24.1 1.7 8.5 9.8 2.6 2 1 1 3 3 3 0 Fez1 AAA_13 PF13166.1 KKK18487.1 - 9.6 4.5 12.6 1.7 7.0 2.5 1.7 1 1 2 3 3 3 0 AAA domain Ribosomal_S4 PF00163.14 KKK18488.1 - 1.5e-30 105.3 1.0 3e-30 104.4 0.7 1.5 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 KKK18488.1 - 5.6e-13 48.0 1.0 5.6e-13 48.0 0.7 2.2 3 0 0 3 3 3 1 S4 domain Cu_bind_like PF02298.12 KKK18489.1 - 0.074 12.8 1.3 0.12 12.1 0.0 2.0 3 0 0 3 3 3 0 Plastocyanin-like domain Podoplanin PF05808.6 KKK18489.1 - 0.083 12.4 1.7 0.088 12.3 0.0 1.9 2 0 0 2 2 2 0 Podoplanin Syndecan PF01034.15 KKK18489.1 - 0.14 11.8 0.7 0.25 11.0 0.5 1.4 1 0 0 1 1 1 0 Syndecan domain VSP PF03302.8 KKK18489.1 - 0.15 10.6 1.8 0.26 9.8 1.3 1.3 1 0 0 1 1 1 0 Giardia variant-specific surface protein SSP160 PF06933.6 KKK18489.1 - 0.78 7.6 13.9 1.4 6.8 3.3 2.3 2 0 0 2 2 2 0 Special lobe-specific silk protein SSP160 MtrF PF09472.5 KKK18489.1 - 2.1 7.6 6.6 3.5 6.9 4.5 1.3 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) Dynamin_N PF00350.18 KKK18490.1 - 5.2e-12 45.9 0.0 2.7e-11 43.5 0.0 2.3 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.18 KKK18490.1 - 4.3e-06 26.6 0.0 0.00093 19.1 0.0 3.0 3 0 0 3 3 3 1 50S ribosome-binding GTPase DUF258 PF03193.11 KKK18490.1 - 1e-05 24.7 0.1 0.00012 21.3 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 KKK18490.1 - 2.5e-05 24.3 0.0 2.5e-05 24.3 0.0 3.6 3 1 1 4 4 4 1 AAA ATPase domain ABC_tran PF00005.22 KKK18490.1 - 0.00027 21.2 0.2 0.004 17.4 0.0 2.7 2 0 0 2 2 2 1 ABC transporter AAA_29 PF13555.1 KKK18490.1 - 0.0074 15.7 0.0 0.023 14.2 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain Gly-rich_Ago1 PF12764.2 KKK18490.1 - 0.0087 16.6 0.9 0.043 14.4 0.6 2.3 1 0 0 1 1 1 1 Glycine-rich region of argonaut Miro PF08477.8 KKK18490.1 - 0.013 15.9 0.0 0.035 14.5 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein TraB PF01963.12 KKK18490.1 - 0.014 14.8 0.5 0.033 13.6 0.3 1.5 1 0 0 1 1 1 0 TraB family AAA_22 PF13401.1 KKK18490.1 - 0.019 15.1 1.6 0.17 11.9 0.0 3.2 3 0 0 3 3 3 0 AAA domain Guanylate_kin PF00625.16 KKK18490.1 - 0.028 13.8 0.0 0.5 9.7 0.0 2.6 2 0 0 2 2 2 0 Guanylate kinase GTP_EFTU PF00009.22 KKK18490.1 - 0.061 12.7 0.0 0.29 10.5 0.0 2.1 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Baculo_PEP_C PF04513.7 KKK18490.1 - 1.3 8.8 7.3 2.2 8.1 0.1 3.8 4 0 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus UPF0016 PF01169.14 KKK18491.1 - 3.1e-41 139.3 25.3 3.6e-21 75.0 5.9 2.2 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 Myb_DNA-binding PF00249.26 KKK18492.1 - 1.3e-07 31.5 0.2 2.9e-07 30.4 0.2 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KKK18492.1 - 0.00013 22.0 0.1 0.00048 20.1 0.1 2.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain Vpu PF00558.14 KKK18492.1 - 2 8.0 4.6 3.6 7.2 0.6 2.7 2 0 0 2 2 2 0 Vpu protein MFS_1 PF07690.11 KKK18493.1 - 1.3e-40 139.1 14.5 1.3e-40 139.1 10.0 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KKK18493.1 - 2.2e-14 52.9 6.4 2.2e-14 52.9 4.5 2.9 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.11 KKK18494.1 - 0.0001 21.1 36.4 0.00024 19.9 21.1 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily UvrD_C PF13361.1 KKK18495.1 - 2.6e-76 257.3 0.0 1.4e-74 251.6 0.0 2.1 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.16 KKK18495.1 - 2.9e-35 122.0 0.5 5.8e-35 121.1 0.3 1.5 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.1 KKK18495.1 - 4.2e-14 52.5 0.0 1e-13 51.2 0.0 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_12 PF13087.1 KKK18495.1 - 8.5e-05 22.0 0.0 0.0041 16.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain Cyt-b5 PF00173.23 KKK18496.1 - 1.5e-14 53.4 0.0 2.5e-14 52.8 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Zip PF02535.17 KKK18497.1 - 4.9e-58 196.6 5.1 5.6e-58 196.4 3.6 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter MRI PF15325.1 KKK18498.1 - 0.53 11.2 3.2 0.91 10.5 2.0 1.6 1 1 0 1 1 1 0 Modulator of retrovirus infection Tom37_C PF11801.3 KKK18499.1 - 8.1e-43 146.1 0.1 1.7e-42 145.1 0.0 1.6 2 0 0 2 2 2 1 Tom37 C-terminal domain Tom37 PF10568.4 KKK18499.1 - 5.7e-27 93.7 1.0 5e-26 90.7 0.0 2.9 4 0 0 4 4 4 1 Outer mitochondrial membrane transport complex protein GST_C_2 PF13410.1 KKK18499.1 - 7.4e-06 25.7 0.1 3.8e-05 23.4 0.0 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain APH PF01636.18 KKK18500.1 - 0.0015 18.3 0.1 0.002 17.9 0.1 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Asp PF00026.18 KKK18514.1 - 1.2e-73 248.1 5.5 1.6e-73 247.7 3.8 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease tRNA-synt_1b PF00579.20 KKK18514.1 - 1.7e-68 230.9 0.0 2.5e-68 230.3 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) TAXi_N PF14543.1 KKK18514.1 - 1.4e-11 44.6 2.1 3e-11 43.5 0.7 2.2 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 KKK18514.1 - 2.7e-06 27.7 0.4 0.012 16.1 0.1 3.6 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.1 KKK18514.1 - 7.6e-05 22.3 0.0 0.00015 21.3 0.0 1.6 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal Ribosomal_S10 PF00338.17 KKK18515.1 - 1.9e-25 88.4 0.0 2.9e-25 87.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e Erv26 PF04148.8 KKK18516.1 - 1.9e-77 259.4 0.0 2e-77 259.3 0.0 1.0 1 0 0 1 1 1 1 Transmembrane adaptor Erv26 DUF3329 PF11808.3 KKK18516.1 - 5.3 7.1 8.4 1.7 8.7 0.4 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF3329) APP_N PF02177.11 KKK18517.1 - 0.012 15.5 0.2 2.7 7.9 0.0 2.1 1 1 1 2 2 2 0 Amyloid A4 N-terminal heparin-binding YjbE PF11106.3 KKK18517.1 - 0.11 12.5 0.3 0.19 11.7 0.2 1.5 1 0 0 1 1 1 0 Exopolysaccharide production protein YjbE Toxin_29 PF08116.6 KKK18517.1 - 1.3 8.8 4.1 18 5.2 0.2 2.3 2 0 0 2 2 2 0 PhTx neurotoxin family WBS_methylT PF12589.3 KKK18519.1 - 3.1e-17 62.8 1.6 5.1e-17 62.1 1.1 1.4 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.7 KKK18519.1 - 5.3e-12 46.0 0.0 9.1e-12 45.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KKK18519.1 - 1.6e-09 38.0 0.0 5.1e-09 36.4 0.0 1.9 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KKK18519.1 - 6.3e-07 29.0 0.0 9.8e-07 28.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KKK18519.1 - 1e-05 26.0 0.0 2.2e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KKK18519.1 - 1.4e-05 25.4 0.0 4.1e-05 23.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KKK18519.1 - 4.5e-05 23.2 0.0 6.4e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KKK18519.1 - 5.9e-05 23.0 0.0 0.00012 22.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 KKK18519.1 - 0.0011 18.5 0.0 0.0018 17.8 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.13 KKK18519.1 - 0.0039 16.3 0.1 0.043 12.9 0.0 2.2 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family CMAS PF02353.15 KKK18519.1 - 0.014 14.4 0.0 0.21 10.6 0.0 2.0 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase Methyltransf_4 PF02390.12 KKK18519.1 - 0.11 11.4 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase Iso_dh PF00180.15 KKK18520.1 - 2.7e-83 279.8 0.0 3.4e-83 279.4 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Proteasome PF00227.21 KKK18521.1 - 6e-47 159.4 0.1 7.1e-32 110.2 0.0 2.3 2 0 0 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.4 KKK18521.1 - 4.8e-12 44.9 0.3 1e-11 43.9 0.0 1.7 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Cyclin PF08613.6 KKK18553.1 - 1e-14 55.1 0.0 4.1e-14 53.2 0.0 2.0 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.18 KKK18553.1 - 0.0029 17.1 0.1 0.0067 16.0 0.0 1.7 1 1 0 1 1 1 1 Cyclin, N-terminal domain Pyrid_oxidase_2 PF13883.1 KKK18554.1 - 7.9e-37 126.6 0.0 1.1e-36 126.1 0.0 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase AreA_N PF07573.6 KKK18555.1 - 1.1e-23 83.5 2.3 1.1e-23 83.5 1.6 3.7 3 0 0 3 3 3 1 Nitrogen regulatory protein AreA N terminus GATA PF00320.22 KKK18555.1 - 3.6e-16 58.2 1.9 7.3e-16 57.2 1.3 1.6 1 0 0 1 1 1 1 GATA zinc finger DUF1752 PF08550.5 KKK18555.1 - 7.9e-14 50.9 3.9 1.5e-13 50.0 2.7 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Ipi1_N PF12333.3 KKK18556.1 - 5.3e-27 93.7 0.9 1.3e-26 92.5 0.0 2.1 2 0 0 2 2 2 1 Rix1 complex component involved in 60S ribosome maturation HEAT_2 PF13646.1 KKK18556.1 - 0.056 13.7 1.1 0.12 12.6 0.3 1.9 1 1 0 1 1 1 0 HEAT repeats HEAT PF02985.17 KKK18556.1 - 0.29 11.3 1.5 14 6.1 0.1 3.1 3 0 0 3 3 3 0 HEAT repeat PAN_4 PF14295.1 KKK18557.1 - 1.3e-07 31.2 36.5 0.0025 17.4 4.6 5.2 5 0 0 5 5 5 4 PAN domain PAN_3 PF08277.7 KKK18557.1 - 0.00015 21.3 33.8 0.0057 16.2 1.6 5.3 5 0 0 5 5 5 3 PAN-like domain VWA_2 PF13519.1 KKK18558.1 - 2.2e-07 31.1 0.9 5.1e-07 29.9 0.6 1.6 1 1 0 1 1 1 1 von Willebrand factor type A domain vWA-TerF-like PF10138.4 KKK18558.1 - 0.0046 16.8 0.0 0.0093 15.8 0.0 1.4 1 0 0 1 1 1 1 vWA found in TerF C terminus PmbA_TldD PF01523.11 KKK18558.1 - 3.1 6.9 5.8 0.44 9.7 0.4 2.0 1 1 1 2 2 2 0 Putative modulator of DNA gyrase Transp_cyt_pur PF02133.10 KKK18559.1 - 8.7e-91 304.6 43.2 1e-90 304.4 29.9 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Pkinase PF00069.20 KKK18560.1 - 6.2e-17 61.6 0.0 1.1e-12 47.6 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KKK18560.1 - 0.00081 18.5 0.0 0.0017 17.5 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase DUF3437 PF11919.3 KKK18560.1 - 0.053 13.2 0.0 0.14 11.8 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3437) PIG-L PF02585.12 KKK18564.1 - 1.9e-25 89.8 0.0 2.6e-25 89.3 0.0 1.2 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase Vir_act_alpha_C PF10400.4 KKK18572.1 - 0.11 12.9 0.1 1.3 9.4 0.1 2.1 2 0 0 2 2 2 0 Virulence activator alpha C-term zf-C2H2 PF00096.21 KKK18573.1 - 4.9e-07 29.7 9.7 0.00028 21.0 0.3 3.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type Fungal_trans PF04082.13 KKK18573.1 - 1.7e-05 23.8 0.0 3.6e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2_jaz PF12171.3 KKK18573.1 - 0.00028 20.9 2.5 0.56 10.4 0.0 3.1 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.1 KKK18573.1 - 0.00033 20.7 5.4 0.00033 20.7 3.7 3.4 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 KKK18573.1 - 0.023 15.0 16.0 0.079 13.3 0.5 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger zf-met PF12874.2 KKK18573.1 - 0.039 14.1 1.0 1.7 8.9 0.1 3.0 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 KKK18573.1 - 0.32 10.9 7.8 0.34 10.8 0.1 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger Myb_DNA-bind_3 PF12776.2 KKK18574.1 - 0.14 12.7 0.5 0.3 11.7 0.2 1.7 1 1 0 1 1 1 0 Myb/SANT-like DNA-binding domain 4HBT_3 PF13622.1 KKK18575.1 - 5.9e-39 134.3 0.1 7.1e-39 134.0 0.1 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily DUF4597 PF15366.1 KKK18576.1 - 1.4 8.5 4.7 13 5.4 0.2 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4597) YscJ_FliF PF01514.12 KKK18577.1 - 0.07 12.2 0.1 0.14 11.2 0.0 1.4 2 0 0 2 2 2 0 Secretory protein of YscJ/FliF family MFS_1 PF07690.11 KKK18579.1 - 1.6e-40 138.9 14.9 2.6e-40 138.2 10.3 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KKK18579.1 - 8.3e-14 50.9 21.8 2.8e-11 42.6 3.8 2.4 2 0 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.8 KKK18579.1 - 3.1e-08 32.3 4.2 6.8e-07 27.8 0.8 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) DUF2275 PF10039.4 KKK18579.1 - 0.1 12.5 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2275) FtsK_SpoIIIE PF01580.13 KKK18580.1 - 0.0017 17.8 0.0 0.0019 17.6 0.0 1.1 1 0 0 1 1 1 1 FtsK/SpoIIIE family B12-binding PF02310.14 KKK18580.1 - 0.003 17.4 0.1 0.0044 16.8 0.0 1.2 1 0 0 1 1 1 1 B12 binding domain Methyltransf_6 PF03737.10 KKK18586.1 - 2e-22 79.6 0.1 2.8e-22 79.2 0.0 1.2 1 0 0 1 1 1 1 Demethylmenaquinone methyltransferase Acetyltransf_2 PF00797.12 KKK18587.1 - 1.7e-38 132.5 0.0 2.5e-38 132.0 0.0 1.2 1 0 0 1 1 1 1 N-acetyltransferase Thiolase_N PF00108.18 KKK18588.1 - 3.5e-76 255.6 4.1 3.5e-76 255.6 2.9 1.5 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 KKK18588.1 - 7.1e-44 148.1 0.3 1.8e-43 146.9 0.2 1.7 1 0 0 1 1 1 1 Thiolase, C-terminal domain Trigger_N PF05697.8 KKK18588.1 - 0.085 12.6 0.1 0.39 10.5 0.1 2.0 2 0 0 2 2 2 0 Bacterial trigger factor protein (TF) MOZ_SAS PF01853.13 KKK18589.1 - 1.7e-79 265.4 0.0 2.4e-79 264.9 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family PHD PF00628.24 KKK18589.1 - 0.00025 20.6 8.6 0.00025 20.6 5.9 2.1 2 0 0 2 2 2 1 PHD-finger zf-MIZ PF02891.15 KKK18589.1 - 0.056 12.9 2.1 0.13 11.7 1.4 1.6 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger BTB_2 PF02214.17 KKK18590.1 - 2.6e-08 33.9 0.0 5.1e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 KKK18590.1 - 3.5e-05 23.7 0.0 5.6e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain DUF4588 PF15251.1 KKK18591.1 - 5.3 6.9 19.5 87 2.9 13.5 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4588) SNF2_N PF00176.18 KKK18592.1 - 9.9e-83 277.3 0.5 1.7e-82 276.6 0.3 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.5 KKK18592.1 - 1.1e-45 154.1 2.8 1.7e-45 153.5 0.7 2.3 2 0 0 2 2 2 1 SLIDE HAND PF09110.6 KKK18592.1 - 6.4e-36 123.1 0.8 6.4e-36 123.1 0.5 3.5 3 0 0 3 3 3 1 HAND Helicase_C PF00271.26 KKK18592.1 - 2.1e-14 53.1 0.0 1.1e-13 50.8 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KKK18592.1 - 1.2e-08 35.0 0.0 5.7e-08 32.8 0.0 2.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 KKK18592.1 - 8.4e-06 25.3 0.0 2.1e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase DEAD_2 PF06733.10 KKK18592.1 - 0.023 14.0 0.1 0.049 13.0 0.1 1.4 1 0 0 1 1 1 0 DEAD_2 AAA_14 PF13173.1 KKK18592.1 - 0.026 14.4 1.0 0.074 12.9 0.1 2.3 2 0 0 2 2 2 0 AAA domain Adap_comp_sub PF00928.16 KKK18593.1 - 1.2e-52 178.5 0.0 2.4e-43 148.1 0.0 2.3 2 1 0 2 2 2 2 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 KKK18593.1 - 9.9e-05 22.0 0.4 0.0002 21.1 0.3 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain NST1 PF13945.1 KKK18593.1 - 0.1 12.6 4.1 0.16 12.0 2.9 1.3 1 0 0 1 1 1 0 Salt tolerance down-regulator TFIIF_alpha PF05793.7 KKK18593.1 - 0.16 10.3 10.3 0.23 9.8 7.1 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) FTCD_C PF04961.7 KKK18593.1 - 0.28 10.5 1.1 0.49 9.7 0.7 1.3 1 0 0 1 1 1 0 Formiminotransferase-cyclodeaminase Pol_alpha_B_N PF08418.5 KKK18593.1 - 0.64 9.5 10.4 1 8.8 7.2 1.3 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal DUF605 PF04652.11 KKK18593.1 - 0.83 8.9 21.3 1.3 8.3 14.7 1.2 1 0 0 1 1 1 0 Vta1 like DUF4536 PF15055.1 KKK18594.1 - 0.0002 21.3 0.1 0.00029 20.8 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4536) PetG PF02529.10 KKK18595.1 - 0.11 12.0 2.1 0.17 11.4 1.4 1.2 1 0 0 1 1 1 0 Cytochrome B6-F complex subunit 5 AAA_23 PF13476.1 KKK18607.1 - 9.9e-27 94.5 1.1 9.9e-27 94.5 0.8 8.1 1 1 1 3 3 3 1 AAA domain SbcCD_C PF13558.1 KKK18607.1 - 1.9e-11 43.6 0.0 6e-11 42.1 0.0 1.9 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit SMC_N PF02463.14 KKK18607.1 - 1.2e-05 24.6 0.0 1.2e-05 24.6 0.0 3.6 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain KNOX2 PF03791.8 KKK18607.1 - 0.0002 20.5 0.2 0.017 14.3 0.0 3.7 3 0 0 3 3 3 1 KNOX2 domain AAA_13 PF13166.1 KKK18607.1 - 0.0025 16.3 133.4 0.023 13.2 15.7 7.2 2 1 4 6 6 6 3 AAA domain AAA_21 PF13304.1 KKK18607.1 - 0.0084 16.1 0.0 0.0084 16.1 0.0 4.5 4 2 1 5 5 5 1 AAA domain MobB PF03205.9 KKK18607.1 - 0.042 13.5 0.2 0.042 13.5 0.1 3.0 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_29 PF13555.1 KKK18607.1 - 0.12 11.9 0.0 0.26 10.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Reo_sigmaC PF04582.7 KKK18607.1 - 0.58 9.2 34.5 1.2 8.2 0.9 6.9 4 3 3 7 7 7 0 Reovirus sigma C capsid protein Rad1 PF02144.11 KKK18608.1 - 4.7e-95 317.4 0.2 5.4e-95 317.2 0.2 1.0 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Chs3p PF12271.3 KKK18608.1 - 0.15 10.9 0.1 0.72 8.7 0.0 1.9 2 0 0 2 2 2 0 Chitin synthase III catalytic subunit DUF485 PF04341.7 KKK18609.1 - 0.17 11.6 2.8 0.19 11.4 2.0 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF485 UPF0197 PF05251.7 KKK18609.1 - 0.19 12.0 9.0 0.96 9.8 6.3 2.0 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0197) Claudin_2 PF13903.1 KKK18609.1 - 1.1 8.9 4.8 1.2 8.7 3.3 1.1 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Bromodomain PF00439.20 KKK18610.1 - 3.1e-25 87.8 0.8 5.8e-25 87.0 0.5 1.4 1 0 0 1 1 1 1 Bromodomain Acetyltransf_1 PF00583.19 KKK18610.1 - 8.2e-10 38.5 0.2 3.7e-09 36.4 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KKK18610.1 - 1.4e-09 37.9 0.4 3.6e-09 36.6 0.1 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 KKK18610.1 - 0.075 12.9 0.1 0.17 11.8 0.1 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 KKK18610.1 - 0.16 11.7 0.0 0.31 10.8 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein PPP4R2 PF09184.6 KKK18611.1 - 1.5e-12 47.6 0.3 2.1e-11 43.8 0.2 2.4 1 1 0 1 1 1 1 PPP4R2 E1-E2_ATPase PF00122.15 KKK18612.1 - 3.4e-51 173.4 0.3 3.4e-51 173.4 0.2 2.1 2 0 0 2 2 2 1 E1-E2 ATPase HMA PF00403.21 KKK18612.1 - 5.8e-46 154.4 0.3 1.9e-11 43.9 0.0 4.4 4 0 0 4 4 4 4 Heavy-metal-associated domain Hydrolase PF00702.21 KKK18612.1 - 1.4e-44 153.0 0.3 2.9e-44 152.0 0.2 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KKK18612.1 - 8.7e-14 52.1 0.0 2.5e-13 50.6 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KKK18612.1 - 0.00054 19.6 1.1 0.0011 18.6 0.1 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase B12-binding PF02310.14 KKK18612.1 - 0.001 18.9 0.0 1.3 8.9 0.0 3.9 4 1 0 4 4 4 1 B12 binding domain GFA PF04828.9 KKK18612.1 - 0.038 13.9 0.2 11 6.0 0.0 3.2 3 0 0 3 3 3 0 Glutathione-dependent formaldehyde-activating enzyme PCI PF01399.22 KKK18613.1 - 4.1e-05 23.8 0.0 6.7e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 PCI domain RGS PF00615.14 KKK18614.1 - 2e-11 44.0 0.0 2.1e-08 34.2 0.0 2.3 2 0 0 2 2 2 2 Regulator of G protein signaling domain NARP1 PF12569.3 KKK18615.1 - 1.9e-213 709.9 26.4 1.2e-211 704.0 11.6 2.5 3 0 0 3 3 3 2 NMDA receptor-regulated protein 1 TPR_11 PF13414.1 KKK18615.1 - 5.5e-21 73.9 30.9 5.4e-06 25.9 1.4 8.7 7 2 1 8 8 8 5 TPR repeat TPR_14 PF13428.1 KKK18615.1 - 1.5e-19 68.7 20.6 0.0038 17.7 0.2 11.5 8 3 4 12 12 10 5 Tetratricopeptide repeat TPR_19 PF14559.1 KKK18615.1 - 1.7e-18 66.6 33.3 0.0017 18.6 0.3 8.5 7 3 2 9 9 9 6 Tetratricopeptide repeat TPR_16 PF13432.1 KKK18615.1 - 7.3e-18 64.7 29.0 0.0018 18.8 1.6 9.7 8 1 2 10 10 10 4 Tetratricopeptide repeat TPR_2 PF07719.12 KKK18615.1 - 4.6e-14 51.1 46.2 0.0002 21.0 0.4 11.7 14 0 0 14 14 11 5 Tetratricopeptide repeat TPR_12 PF13424.1 KKK18615.1 - 7.5e-12 45.0 34.0 0.0055 16.6 0.3 8.6 6 3 2 8 8 8 5 Tetratricopeptide repeat TPR_17 PF13431.1 KKK18615.1 - 1.2e-09 37.6 15.9 0.092 12.9 0.0 8.4 9 0 0 9 9 7 2 Tetratricopeptide repeat Apc3 PF12895.2 KKK18615.1 - 1.4e-06 28.3 20.0 0.00016 21.7 1.6 6.0 5 1 1 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 KKK18615.1 - 5.3e-06 26.2 14.8 0.006 16.4 1.9 5.9 5 2 1 6 6 6 1 Tetratricopeptide repeat TPR_1 PF00515.23 KKK18615.1 - 3.9e-05 23.0 37.9 4.4e-05 22.9 0.3 9.7 12 0 0 12 12 11 2 Tetratricopeptide repeat TPR_8 PF13181.1 KKK18615.1 - 0.00011 21.7 23.4 0.016 14.9 0.1 8.4 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_7 PF13176.1 KKK18615.1 - 0.00057 19.4 6.9 2.5 8.1 0.1 6.5 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_3 PF07720.7 KKK18615.1 - 0.0041 16.8 2.5 0.33 10.7 0.1 3.9 3 0 0 3 3 2 1 Tetratricopeptide repeat Rapsyn_N PF10579.4 KKK18615.1 - 0.0087 15.8 4.8 0.73 9.6 0.1 4.4 3 1 1 4 4 4 1 Rapsyn N-terminal myristoylation and linker region BTAD PF03704.12 KKK18615.1 - 0.013 15.8 0.2 0.013 15.8 0.1 4.2 5 0 0 5 5 4 0 Bacterial transcriptional activator domain TPR_4 PF07721.9 KKK18615.1 - 0.041 14.3 3.9 0.4 11.2 0.1 4.3 5 0 0 5 5 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 KKK18615.1 - 0.047 14.1 25.4 1.2 9.7 0.2 9.0 10 0 0 10 10 10 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 KKK18615.1 - 1 9.2 13.7 7.3 6.5 0.1 5.6 7 1 0 7 7 6 0 Fis1 C-terminal tetratricopeptide repeat DUF4449 PF14613.1 KKK18616.1 - 7.4e-64 214.6 0.2 7.4e-64 214.6 0.2 2.9 2 1 1 3 3 3 1 Protein of unknown function (DUF4449) Sec34 PF04136.10 KKK18616.1 - 0.046 13.4 0.0 3.7 7.2 0.0 2.8 2 0 0 2 2 2 0 Sec34-like family Corona_S2 PF01601.11 KKK18616.1 - 0.081 11.0 0.1 0.13 10.3 0.1 1.2 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein AIRC PF00731.15 KKK18617.1 - 7.1e-59 197.3 2.5 1.4e-58 196.3 1.7 1.5 1 0 0 1 1 1 1 AIR carboxylase ATP-grasp PF02222.17 KKK18617.1 - 1.7e-53 180.4 0.0 6.6e-53 178.5 0.0 1.9 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp_4 PF13535.1 KKK18617.1 - 4.3e-11 42.8 0.0 1.4e-10 41.2 0.0 1.8 1 1 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.12 KKK18617.1 - 1.6e-06 27.5 0.0 3.9e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATPgrasp_Ter PF15632.1 KKK18617.1 - 0.00026 19.8 0.0 0.17 10.6 0.0 2.8 3 0 0 3 3 3 2 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 KKK18617.1 - 0.00039 19.8 0.0 0.0084 15.5 0.0 2.4 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus 2-Hacid_dh_C PF02826.14 KKK18617.1 - 0.0027 16.9 0.0 0.0052 15.9 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 KKK18617.1 - 0.0075 16.1 0.0 0.021 14.6 0.0 1.8 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase XdhC_C PF13478.1 KKK18617.1 - 0.015 15.6 0.0 0.037 14.3 0.0 1.7 1 0 0 1 1 1 0 XdhC Rossmann domain CoA_binding_2 PF13380.1 KKK18617.1 - 0.033 14.3 0.7 18 5.5 0.0 3.6 2 1 1 3 3 3 0 CoA binding domain ATP-grasp_3 PF02655.9 KKK18617.1 - 0.034 14.0 0.0 0.092 12.6 0.0 1.9 1 1 0 1 1 1 0 ATP-grasp domain 3HCDH_N PF02737.13 KKK18617.1 - 0.041 13.5 0.1 0.12 12.0 0.1 1.9 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PrpR_N PF06506.6 KKK18617.1 - 0.083 12.2 1.8 0.14 11.5 0.1 2.1 2 0 0 2 2 2 0 Propionate catabolism activator Asp-B-Hydro_N PF05279.6 KKK18622.1 - 1.1 9.0 5.8 2.5 7.8 4.0 1.5 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Thioredoxin PF00085.15 KKK18623.1 - 2.2e-18 65.8 0.5 4.8e-18 64.7 0.4 1.6 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 KKK18623.1 - 1.5e-05 25.0 0.0 1.8e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.5 KKK18623.1 - 0.00083 18.9 0.0 0.0009 18.8 0.0 1.2 1 0 0 1 1 1 1 Redoxin Thioredoxin_2 PF13098.1 KKK18623.1 - 0.0051 16.9 0.2 0.012 15.8 0.2 1.6 1 1 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.16 KKK18623.1 - 0.0064 16.1 0.0 0.0073 15.9 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_9 PF14595.1 KKK18623.1 - 0.0086 15.6 0.0 0.01 15.3 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.1 KKK18623.1 - 0.085 12.8 0.0 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like Kelch_4 PF13418.1 KKK18624.1 - 1.6e-23 82.1 2.1 4.9e-09 35.8 0.0 5.1 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_5 PF13854.1 KKK18624.1 - 2.5e-23 81.5 0.3 8.7e-06 25.5 0.1 5.4 5 0 0 5 5 5 4 Kelch motif Kelch_3 PF13415.1 KKK18624.1 - 9.4e-22 76.6 2.3 5.2e-09 36.0 0.0 5.1 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_6 PF13964.1 KKK18624.1 - 9.4e-21 73.0 2.6 5.8e-06 26.2 0.0 5.0 4 1 1 5 5 5 4 Kelch motif Kelch_1 PF01344.20 KKK18624.1 - 1.9e-17 62.5 0.5 0.0015 17.9 0.0 4.4 4 0 0 4 4 4 4 Kelch motif Kelch_2 PF07646.10 KKK18624.1 - 4.1e-17 61.1 0.2 4.3e-05 23.0 0.0 4.4 4 0 0 4 4 4 3 Kelch motif BTB PF00651.26 KKK18624.1 - 4.5e-09 36.2 0.0 9e-09 35.3 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.10 KKK18624.1 - 0.089 12.6 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 BTB And C-terminal Kelch WD40 PF00400.27 KKK18625.1 - 9.5e-25 85.5 16.6 1.4e-07 31.1 0.0 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat eIF2A PF08662.6 KKK18625.1 - 3.6e-05 23.5 0.3 0.0026 17.4 0.1 2.5 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Amidase PF01425.16 KKK18626.1 - 3.9e-06 25.9 0.0 0.025 13.4 0.0 2.4 3 0 0 3 3 3 2 Amidase Glyco_hydro_1 PF00232.13 KKK18627.1 - 7e-154 512.3 0.0 9.3e-154 511.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Sel1 PF08238.7 KKK18628.1 - 6.9e-41 137.7 39.9 2.1e-05 24.9 0.2 12.5 12 0 0 12 12 12 9 Sel1 repeat TPR_16 PF13432.1 KKK18628.1 - 0.0068 17.0 14.3 0.67 10.7 0.3 5.9 5 2 1 6 6 6 1 Tetratricopeptide repeat TPR_14 PF13428.1 KKK18628.1 - 0.0089 16.5 0.1 4.2 8.2 0.1 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 KKK18628.1 - 0.46 10.3 9.9 26 4.8 0.0 5.9 6 2 1 7 7 7 0 Tetratricopeptide repeat TPR_1 PF00515.23 KKK18628.1 - 8.8 6.1 0.0 8.8 6.1 0.0 6.8 8 0 0 8 8 8 0 Tetratricopeptide repeat Mut7-C PF01927.11 KKK18629.1 - 0.091 12.7 0.4 0.77 9.7 0.0 2.1 2 0 0 2 2 2 0 Mut7-C RNAse domain DUF1192 PF06698.6 KKK18629.1 - 0.12 12.1 5.2 1.4 8.8 0.3 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF1192) WD40 PF00400.27 KKK18630.1 - 2.3e-13 49.4 7.1 1e-06 28.3 0.1 4.8 5 0 0 5 5 5 3 WD domain, G-beta repeat eIF2A PF08662.6 KKK18630.1 - 0.00049 19.8 0.0 0.6 9.7 0.0 2.7 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 KKK18630.1 - 0.0027 16.0 0.0 0.0071 14.6 0.0 1.6 1 1 0 2 2 2 1 Cytochrome D1 heme domain RNA_pol_Rpb1_1 PF04997.7 KKK18631.1 - 2.7e-121 404.9 0.0 4.3e-121 404.2 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.12 KKK18631.1 - 1.2e-104 349.4 0.1 2.1e-104 348.6 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 KKK18631.1 - 1.6e-71 239.5 0.0 3.9e-71 238.3 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.9 KKK18631.1 - 2.2e-63 213.3 1.1 4.2e-63 212.4 0.7 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.13 KKK18631.1 - 3.1e-46 156.9 0.0 8.5e-46 155.5 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.7 KKK18631.1 - 2.3e-42 143.9 7.5 2.3e-42 143.9 5.2 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.12 KKK18631.1 - 3.3e-37 126.5 0.1 7.9e-37 125.3 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.8 KKK18631.1 - 3.3e-11 42.3 204.0 0.069 13.2 8.9 14.3 9 3 5 15 15 15 12 RNA polymerase Rpb1 C-terminal repeat GST_C_3 PF14497.1 KKK18632.1 - 1.8e-10 41.2 0.0 2.8e-10 40.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 KKK18632.1 - 1.7e-05 24.9 0.1 0.00017 21.7 0.0 2.2 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KKK18632.1 - 3.4e-05 23.6 0.0 6.6e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Pro_isomerase PF00160.16 KKK18632.1 - 0.023 14.9 0.0 0.035 14.3 0.0 1.3 1 1 0 1 1 1 0 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TFIIA PF03153.8 KKK18633.1 - 2.7e-102 343.5 0.2 3e-102 343.3 0.1 1.0 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit SCA7 PF08313.7 KKK18645.1 - 4.6e-34 115.8 0.8 1.5e-33 114.1 0.6 1.9 1 0 0 1 1 1 1 SCA7, zinc-binding domain DUF3505 PF12013.3 KKK18645.1 - 0.15 12.3 0.3 0.15 12.3 0.2 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF3505) BTV_NS2 PF04514.7 KKK18645.1 - 0.6 8.9 11.0 1.3 7.7 7.6 1.5 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 MIP-T3 PF10243.4 KKK18645.1 - 2.6 6.4 30.4 0.11 10.9 17.3 1.4 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 U79_P34 PF03064.11 KKK18645.1 - 6 6.3 18.3 16 4.9 12.7 1.8 1 0 0 1 1 1 0 HSV U79 / HCMV P34 ketoacyl-synt PF00109.21 KKK18646.1 - 1.8e-59 201.3 5.8 2e-59 201.1 1.0 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 KKK18646.1 - 1.2e-32 112.2 2.0 8e-32 109.5 1.2 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.18 KKK18646.1 - 8.7e-05 21.6 0.2 0.00018 20.5 0.0 1.5 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 KKK18646.1 - 0.0038 16.6 2.3 0.073 12.4 0.3 3.1 3 0 0 3 3 3 1 Thiolase, C-terminal domain Ribophorin_I PF04597.9 KKK18647.1 - 5.9e-158 525.9 0.1 6.7e-158 525.7 0.1 1.0 1 0 0 1 1 1 1 Ribophorin I mRNA_cap_enzyme PF01331.14 KKK18648.1 - 1e-50 172.1 0.3 1.3e-50 171.7 0.2 1.1 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.10 KKK18648.1 - 1.3e-21 76.9 0.0 2.7e-21 75.8 0.0 1.6 1 1 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.16 KKK18648.1 - 1.4e-08 34.3 0.3 2.7e-07 30.1 0.2 2.3 1 1 0 1 1 1 1 ATP dependent DNA ligase domain DLH PF01738.13 KKK18649.1 - 8.2e-05 21.9 0.0 0.0002 20.7 0.0 1.6 2 0 0 2 2 2 1 Dienelactone hydrolase family SnoaL PF07366.7 KKK18649.1 - 0.001 18.6 0.0 0.0014 18.2 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.2 KKK18649.1 - 0.0085 16.4 0.0 0.025 14.9 0.0 1.8 1 1 1 2 2 2 1 SnoaL-like domain Indigoidine_A PF04227.7 KKK18650.1 - 7.8e-110 366.6 0.4 3.1e-108 361.4 0.3 2.2 1 1 0 1 1 1 1 Indigoidine synthase A like protein PfkB PF00294.19 KKK18650.1 - 3.2e-19 69.1 1.9 1.3e-10 40.9 0.2 2.9 2 1 0 2 2 2 2 pfkB family carbohydrate kinase LSM PF01423.17 KKK18656.1 - 1.9e-18 65.7 0.0 2.1e-18 65.6 0.0 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 KKK18656.1 - 0.0018 18.1 0.1 0.002 17.9 0.1 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain UnbV_ASPIC PF07593.7 KKK18656.1 - 0.041 13.5 0.0 0.056 13.1 0.0 1.2 1 0 0 1 1 1 0 ASPIC and UnbV His_Phos_2 PF00328.17 KKK18657.1 - 6.3e-119 397.3 0.7 8.8e-119 396.8 0.2 1.5 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 2) RimK PF08443.6 KKK18657.1 - 7.2e-06 25.6 0.0 1.5e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 RimK-like ATP-grasp domain Mito_fiss_reg PF05308.6 KKK18657.1 - 0.0076 15.6 5.7 0.02 14.2 3.9 1.9 1 0 0 1 1 1 1 Mitochondrial fission regulator N-SET PF11764.3 KKK18658.1 - 1.7e-49 167.9 0.9 1.7e-49 167.9 0.6 2.8 3 1 0 3 3 3 1 COMPASS (Complex proteins associated with Set1p) component N SET_assoc PF11767.3 KKK18658.1 - 6e-26 89.5 0.6 1.2e-25 88.6 0.4 1.5 1 0 0 1 1 1 1 Histone lysine methyltransferase SET associated SET PF00856.23 KKK18658.1 - 1.6e-22 80.5 0.1 1.6e-22 80.5 0.1 3.3 3 2 0 3 3 3 1 SET domain RRM_1 PF00076.17 KKK18658.1 - 5.7e-05 22.6 0.0 0.00016 21.2 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Rad60-SLD PF11976.3 KKK18659.1 - 4.4e-21 74.3 0.0 6.8e-18 64.1 0.1 2.3 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 KKK18659.1 - 0.0017 17.6 0.0 0.17 11.2 0.0 2.5 2 1 0 2 2 2 2 Ubiquitin family DMRL_synthase PF00885.14 KKK18660.1 - 6.8e-45 152.2 0.0 1.4e-44 151.2 0.0 1.5 1 1 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase SIS PF01380.17 KKK18661.1 - 6.5e-56 187.5 0.0 3.2e-30 104.4 0.0 2.3 2 0 0 2 2 2 2 SIS domain GATase_2 PF00310.16 KKK18661.1 - 8e-27 93.8 0.0 3.2e-19 68.8 0.0 2.3 1 1 1 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 KKK18661.1 - 9.5e-20 70.9 0.0 1.9e-19 69.9 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 KKK18661.1 - 5.9e-12 45.4 0.0 1.2e-11 44.3 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.1 KKK18661.1 - 2.1e-08 33.2 0.0 4.1e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SIS_2 PF13580.1 KKK18661.1 - 0.069 12.8 0.0 0.26 10.9 0.0 2.1 2 0 0 2 2 2 0 SIS domain Sec2p PF06428.6 KKK18662.1 - 1.3e-27 95.6 12.2 1.3e-27 95.6 8.4 2.4 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p DUF3584 PF12128.3 KKK18662.1 - 0.0007 17.0 16.7 0.001 16.5 11.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Reo_sigmaC PF04582.7 KKK18662.1 - 0.0012 18.1 4.8 0.028 13.6 3.7 2.2 1 1 1 2 2 2 1 Reovirus sigma C capsid protein DUF1759 PF03564.10 KKK18662.1 - 0.39 10.5 6.1 0.13 12.0 0.9 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF1759) Atg14 PF10186.4 KKK18662.1 - 0.72 8.7 19.5 0.66 8.8 7.6 2.4 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 3-PAP PF12578.3 KKK18662.1 - 3.2 7.6 8.3 0.29 10.9 0.6 2.9 3 1 1 4 4 4 0 Myotubularin-associated protein IncA PF04156.9 KKK18662.1 - 4.3 6.8 21.3 0.93 9.0 3.2 2.4 1 1 1 2 2 2 0 IncA protein Filament PF00038.16 KKK18662.1 - 5 6.4 24.5 2 7.8 14.4 2.2 2 1 0 2 2 2 0 Intermediate filament protein dsDNA_bind PF01984.15 KKK18663.1 - 1.3e-36 124.8 15.0 1.5e-36 124.6 10.4 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain DUF4615 PF15393.1 KKK18663.1 - 0.0024 18.0 1.1 0.0037 17.4 0.7 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4615) Protamine_P2 PF00841.14 KKK18663.1 - 1.6 9.3 4.5 0.32 11.5 0.3 2.0 1 1 1 2 2 2 0 Sperm histone P2 Rap1_C PF11626.3 KKK18663.1 - 5 7.0 6.1 5.9 6.8 0.5 2.6 2 1 1 3 3 3 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Coq4 PF05019.8 KKK18664.1 - 8.5e-100 332.2 0.0 1e-99 331.9 0.0 1.0 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 SET PF00856.23 KKK18665.1 - 4.8e-20 72.4 0.0 7.8e-20 71.8 0.0 1.3 1 0 0 1 1 1 1 SET domain ApbA_C PF08546.6 KKK18666.1 - 4.7e-35 120.3 0.1 7.8e-35 119.6 0.1 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 KKK18666.1 - 1.9e-22 79.3 0.0 5.6e-21 74.5 0.0 2.1 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Sas10_Utp3 PF04000.10 KKK18667.1 - 2e-19 69.5 0.7 2e-19 69.5 0.5 1.8 2 0 0 2 2 2 1 Sas10/Utp3/C1D family Hid1 PF12722.2 KKK18667.1 - 1.3 6.6 13.5 1.4 6.4 9.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein GAGA_bind PF06217.7 KKK18667.1 - 5.8 6.7 15.1 7.3 6.4 10.5 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family DUF2201_N PF13203.1 KKK18667.1 - 6.1 5.9 16.1 7.6 5.6 11.2 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain adh_short PF00106.20 KKK18679.1 - 4.5e-21 75.4 0.6 5.6e-21 75.1 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KKK18679.1 - 4.5e-18 65.8 0.0 6e-18 65.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KKK18679.1 - 5.5e-14 52.2 0.1 7.3e-14 51.8 0.1 1.2 1 0 0 1 1 1 1 KR domain ADH_zinc_N PF00107.21 KKK18679.1 - 0.056 12.9 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Fungal_trans_2 PF11951.3 KKK18687.1 - 6.4e-09 34.8 0.6 8.3e-09 34.5 0.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Velvet PF11754.3 KKK18688.1 - 7.5e-55 185.6 0.0 4.4e-46 157.0 0.0 2.0 2 0 0 2 2 2 2 Velvet factor WD40 PF00400.27 KKK18690.1 - 1.4e-81 265.6 23.3 1.4e-13 50.1 0.1 8.6 8 1 0 8 8 8 8 WD domain, G-beta repeat eIF2A PF08662.6 KKK18690.1 - 2.3e-10 40.5 0.3 0.0031 17.2 0.0 3.7 2 2 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 KKK18690.1 - 1.2e-08 33.5 7.2 0.13 10.3 0.1 5.5 3 2 3 6 6 6 4 Nucleoporin Nup120/160 NLE PF08154.7 KKK18690.1 - 7.3e-06 25.9 0.0 1.5e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 NLE (NUC135) domain FAD_binding_9 PF08021.6 KKK18690.1 - 0.008 16.1 0.0 0.23 11.4 0.0 2.6 2 0 0 2 2 2 1 Siderophore-interacting FAD-binding domain MutS_V PF00488.16 KKK18691.1 - 3.3e-75 252.5 0.4 6e-75 251.6 0.3 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 KKK18691.1 - 2.9e-35 121.9 3.2 2.9e-35 121.9 2.2 2.1 2 0 0 2 2 2 1 MutS domain III MutS_IV PF05190.13 KKK18691.1 - 6.4e-14 51.9 0.4 1.7e-13 50.5 0.1 2.0 2 0 0 2 2 2 1 MutS family domain IV MutS_II PF05188.12 KKK18691.1 - 8.5e-11 42.0 0.3 2.4e-10 40.5 0.2 1.8 1 0 0 1 1 1 1 MutS domain II zf-C3HC4_3 PF13920.1 KKK18692.1 - 1.9e-05 24.2 9.5 1.9e-05 24.2 6.6 3.1 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) SWIB PF02201.13 KKK18693.1 - 5.9e-23 80.3 0.2 2.2e-22 78.4 0.0 1.9 2 0 0 2 2 2 1 SWIB/MDM2 domain DEK_C PF08766.6 KKK18693.1 - 7e-16 57.7 0.1 1.6e-15 56.5 0.1 1.7 1 0 0 1 1 1 1 DEK C terminal domain Herpes_LMP2 PF07415.6 KKK18693.1 - 2 6.9 4.4 2.6 6.5 3.0 1.1 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein eIF2A PF08662.6 KKK18694.1 - 7.7e-40 136.6 2.8 3.1e-38 131.4 0.6 3.6 3 1 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A RRM_5 PF13893.1 KKK18694.1 - 2.3e-07 30.5 0.0 5.7e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KKK18694.1 - 3.3e-07 29.8 0.0 9e-07 28.4 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KKK18694.1 - 2.2e-06 27.5 0.0 1.2e-05 25.2 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 KKK18694.1 - 0.0027 17.5 0.0 0.079 12.8 0.0 3.0 2 0 0 2 2 2 1 WD domain, G-beta repeat CAP PF00188.21 KKK18695.1 - 6.4e-20 71.8 5.4 9.7e-20 71.3 3.7 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family TMEM171 PF15471.1 KKK18695.1 - 0.13 10.9 1.0 0.19 10.4 0.7 1.2 1 0 0 1 1 1 0 Transmembrane protein family 171 Sec10 PF07393.6 KKK18696.1 - 1.5e-181 605.1 3.5 1.8e-181 604.9 2.4 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 F-box-like PF12937.2 KKK18696.1 - 6.2e-05 22.6 0.1 0.00016 21.3 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KKK18696.1 - 0.00098 18.7 0.1 0.0022 17.6 0.1 1.6 1 0 0 1 1 1 1 F-box domain RINT1_TIP1 PF04437.8 KKK18696.1 - 0.0037 15.8 0.6 0.0066 15.0 0.1 1.6 2 0 0 2 2 2 1 RINT-1 / TIP-1 family Cytochrom_C1 PF02167.10 KKK18697.1 - 1.9e-80 269.6 0.0 2.4e-80 269.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.1 KKK18697.1 - 0.021 14.9 0.0 0.049 13.7 0.0 1.6 1 0 0 1 1 1 0 Cytochrome C oxidase, cbb3-type, subunit III AIG2_2 PF13772.1 KKK18698.1 - 9.7e-05 22.4 0.6 0.00053 20.0 0.1 2.4 2 1 0 2 2 2 1 AIG2-like family DAHP_synth_1 PF00793.15 KKK18699.1 - 4.8e-83 277.9 0.1 2.3e-82 275.7 0.1 1.8 1 1 0 1 1 1 1 DAHP synthetase I family EBP PF05241.7 KKK18700.1 - 3.2e-46 156.7 4.4 4.1e-46 156.4 3.1 1.0 1 0 0 1 1 1 1 Emopamil binding protein DUF3611 PF12263.3 KKK18700.1 - 0.029 13.7 0.2 0.059 12.7 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3611) DUF95 PF01944.12 KKK18700.1 - 0.056 13.0 0.1 0.1 12.2 0.1 1.4 1 0 0 1 1 1 0 Integral membrane protein DUF95 F-box-like PF12937.2 KKK18701.1 - 3.5e-10 39.4 1.0 3e-07 30.0 0.1 2.7 2 0 0 2 2 2 2 F-box-like F-box PF00646.28 KKK18701.1 - 1.5e-07 30.8 0.4 0.017 14.7 0.0 2.7 2 0 0 2 2 2 2 F-box domain DUF221 PF02714.10 KKK18702.1 - 7.1e-99 330.7 18.9 1.1e-98 330.0 13.1 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF221 DUF4463 PF14703.1 KKK18702.1 - 1.1e-24 86.7 0.5 2.1e-24 85.8 0.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) RSN1_TM PF13967.1 KKK18702.1 - 2.4e-17 62.9 0.4 2.4e-17 62.9 0.3 3.0 3 1 0 3 3 3 1 Late exocytosis, associated with Golgi transport RRM_6 PF14259.1 KKK18702.1 - 0.00017 21.4 0.0 0.13 12.2 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-DHHC PF01529.15 KKK18702.1 - 2.3 7.5 6.7 0.2 11.0 0.1 2.6 3 1 0 3 3 3 0 DHHC palmitoyltransferase hDGE_amylase PF14701.1 KKK18703.1 - 1.3e-177 590.9 0.1 1.7e-177 590.5 0.1 1.1 1 0 0 1 1 1 1 glucanotransferase domain of human glycogen debranching enzyme GDE_C PF06202.9 KKK18703.1 - 1.1e-110 369.9 0.1 2.5e-110 368.6 0.0 1.6 2 0 0 2 2 2 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.1 KKK18703.1 - 5.4e-88 294.5 0.0 8.2e-88 293.9 0.0 1.3 1 0 0 1 1 1 1 central domain of human glycogen debranching enzyme hGDE_N PF14699.1 KKK18703.1 - 1.4e-27 95.3 0.0 3.2e-27 94.1 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme Alpha-amylase PF00128.19 KKK18703.1 - 0.00021 20.7 0.1 0.05 12.9 0.0 2.4 2 0 0 2 2 2 2 Alpha amylase, catalytic domain NAD_Gly3P_dh_N PF01210.18 KKK18704.1 - 1.3e-47 161.4 0.0 2.2e-47 160.7 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.9 KKK18704.1 - 2.3e-43 147.4 0.2 3.4e-43 146.9 0.1 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus F420_oxidored PF03807.12 KKK18704.1 - 0.047 14.1 0.0 12 6.4 0.0 2.4 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent SLX9 PF15341.1 KKK18705.1 - 1.3e-35 122.4 9.5 1.7e-35 122.0 6.6 1.2 1 0 0 1 1 1 1 Ribosome biogenesis protein SLX9 Neugrin PF06413.6 KKK18705.1 - 0.015 15.1 5.3 0.26 11.0 1.2 2.1 1 1 1 2 2 2 0 Neugrin HrpJ PF07201.6 KKK18705.1 - 0.064 13.2 2.7 0.13 12.2 1.9 1.5 1 1 0 1 1 1 0 HrpJ-like domain DUF2413 PF10310.4 KKK18705.1 - 0.13 11.0 5.6 0.15 10.8 3.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Calpain_inhib PF00748.14 KKK18705.1 - 0.37 11.1 5.9 0.22 11.8 2.2 1.8 1 1 1 2 2 2 0 Calpain inhibitor F-box-like PF12937.2 KKK18706.1 - 0.0024 17.5 0.8 0.0058 16.3 0.5 1.7 1 0 0 1 1 1 1 F-box-like LRR_1 PF00560.28 KKK18706.1 - 1.9 8.8 7.3 0.74 10.0 1.2 3.3 3 0 0 3 3 3 0 Leucine Rich Repeat LRR_7 PF13504.1 KKK18706.1 - 9.4 6.9 8.7 2.4 8.7 0.6 4.2 5 0 0 5 5 5 0 Leucine rich repeat CVNH PF08881.5 KKK18707.1 - 3.8e-22 78.4 0.1 4.2e-22 78.3 0.0 1.0 1 0 0 1 1 1 1 CVNH domain ETX_MTX2 PF03318.8 KKK18707.1 - 0.035 13.6 0.1 0.047 13.2 0.1 1.1 1 0 0 1 1 1 0 Clostridium epsilon toxin ETX/Bacillus mosquitocidal toxin MTX2 Mito_carr PF00153.22 KKK18708.1 - 1.4e-64 213.8 0.1 2.1e-21 75.3 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF1049 PF06305.6 KKK18708.1 - 0.015 14.7 0.0 27 4.3 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1049) CRF PF00473.12 KKK18708.1 - 0.052 13.6 0.1 0.75 9.9 0.0 2.5 2 0 0 2 2 2 0 Corticotropin-releasing factor family Ras PF00071.17 KKK18709.1 - 1.1e-63 213.4 0.2 1.3e-63 213.1 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KKK18709.1 - 1.8e-21 76.8 0.1 2.6e-21 76.2 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KKK18709.1 - 2.5e-13 49.6 0.1 3.3e-13 49.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 KKK18709.1 - 5.1e-08 32.8 0.1 8e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 KKK18709.1 - 5.9e-05 22.3 0.1 0.00011 21.4 0.1 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 KKK18709.1 - 6.4e-05 22.4 0.1 0.00023 20.6 0.1 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 KKK18709.1 - 0.00012 22.1 0.0 0.00037 20.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_15 PF13175.1 KKK18709.1 - 0.00087 18.4 0.1 0.0012 18.0 0.1 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.1 KKK18709.1 - 0.0012 18.7 0.1 0.0032 17.3 0.1 1.7 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 KKK18709.1 - 0.0027 16.9 0.1 0.0056 15.8 0.1 1.6 1 1 0 1 1 1 1 Protein of unknown function, DUF258 SRPRB PF09439.5 KKK18709.1 - 0.015 14.5 0.0 0.023 13.9 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit ABC_tran PF00005.22 KKK18709.1 - 0.018 15.3 0.2 0.023 14.9 0.1 1.5 1 1 0 1 1 1 0 ABC transporter AAA_16 PF13191.1 KKK18709.1 - 0.018 15.0 0.3 0.04 13.9 0.2 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.1 KKK18709.1 - 0.025 14.1 0.1 0.049 13.2 0.0 1.4 1 1 0 1 1 1 0 AAA domain DUF4468 PF14730.1 KKK18709.1 - 0.056 13.1 0.1 0.18 11.5 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4468) with TBP-like fold SpoIIID PF12116.3 KKK18709.1 - 0.072 13.0 0.1 1 9.3 0.0 2.2 2 0 0 2 2 2 0 Stage III sporulation protein D FeoB_N PF02421.13 KKK18709.1 - 0.081 12.2 0.1 0.22 10.7 0.0 1.7 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_29 PF13555.1 KKK18709.1 - 0.11 12.0 0.0 0.24 10.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.9 KKK18709.1 - 0.11 12.2 0.0 0.25 11.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Chromo PF00385.19 KKK18710.1 - 1.1e-08 34.6 0.5 3.3e-08 33.0 0.3 1.9 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DSRB PF10781.4 KKK18710.1 - 0.066 12.7 0.0 0.21 11.0 0.0 1.8 1 0 0 1 1 1 0 Dextransucrase DSRB AAA_2 PF07724.9 KKK18711.1 - 1.9e-39 135.3 0.0 2e-38 132.0 0.0 2.6 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 KKK18711.1 - 6.7e-15 55.4 0.0 1.4e-14 54.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 KKK18711.1 - 2.6e-08 33.6 0.0 7e-08 32.2 0.0 1.7 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.9 KKK18711.1 - 2.4e-06 27.3 0.0 5.3e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 KKK18711.1 - 7.2e-05 22.3 0.0 0.022 14.2 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_22 PF13401.1 KKK18711.1 - 0.00011 22.3 0.3 0.003 17.6 0.2 2.4 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KKK18711.1 - 0.00017 21.6 2.2 0.00045 20.2 0.1 2.4 1 1 1 2 2 2 1 AAA ATPase domain Mg_chelatase PF01078.16 KKK18711.1 - 0.0002 20.6 0.2 0.011 14.9 0.0 3.0 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 KKK18711.1 - 0.0008 18.8 0.0 0.0016 17.9 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_17 PF13207.1 KKK18711.1 - 0.0016 19.2 0.2 0.0037 18.0 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_24 PF13479.1 KKK18711.1 - 0.0036 16.9 0.0 0.0073 15.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 KKK18711.1 - 0.0038 16.2 0.6 0.074 12.0 0.0 2.7 3 0 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 KKK18711.1 - 0.02 14.7 0.0 0.045 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 KKK18711.1 - 0.022 14.1 0.0 0.044 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 KKK18711.1 - 0.033 13.8 0.0 1.3 8.6 0.0 2.4 2 0 0 2 2 2 0 NACHT domain RNA_helicase PF00910.17 KKK18711.1 - 0.05 13.7 0.0 0.1 12.7 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_3 PF07726.6 KKK18711.1 - 0.063 12.8 0.0 0.17 11.5 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activ_2 PF14532.1 KKK18711.1 - 0.074 13.1 0.0 0.42 10.6 0.0 2.2 2 1 0 2 2 2 0 Sigma-54 interaction domain AAA_33 PF13671.1 KKK18711.1 - 0.1 12.4 0.4 0.76 9.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 KKK18711.1 - 0.13 12.5 0.4 0.45 10.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 KKK18711.1 - 0.13 11.3 0.0 0.25 10.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 DUF2744 PF10910.3 KKK18712.1 - 0.086 12.6 0.1 0.15 11.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2744) PfkB PF00294.19 KKK18713.1 - 2.3e-18 66.3 0.0 3.9e-18 65.6 0.0 1.3 1 1 0 1 1 1 1 pfkB family carbohydrate kinase Brix PF04427.13 KKK18714.1 - 3.4e-30 105.1 0.0 4.4e-30 104.7 0.0 1.1 1 0 0 1 1 1 1 Brix domain PBP1_TM PF14812.1 KKK18714.1 - 0.07 13.4 3.4 0.21 11.9 2.4 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal F-box-like PF12937.2 KKK18715.1 - 0.00014 21.4 0.1 0.00014 21.4 0.1 1.8 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KKK18715.1 - 0.00096 18.7 0.5 0.0027 17.2 0.3 1.8 1 0 0 1 1 1 1 F-box domain DUF1838 PF08894.6 KKK18715.1 - 0.057 12.6 0.0 0.086 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1838) Abp2 PF09441.5 KKK18716.1 - 3.8e-88 293.9 0.1 5.6e-88 293.4 0.1 1.2 1 0 0 1 1 1 1 ARS binding protein 2 Surfac_D-trimer PF09006.6 KKK18716.1 - 0.22 11.2 2.0 0.45 10.2 1.4 1.5 1 0 0 1 1 1 0 Lung surfactant protein D coiled-coil trimerisation Cpn60_TCP1 PF00118.19 KKK18731.1 - 2.6e-133 445.2 10.5 3e-133 444.9 7.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Toxin_51 PF15531.1 KKK18731.1 - 0.092 12.5 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Putative toxin 51 PAD_M PF08527.5 KKK18731.1 - 0.095 12.0 0.2 0.87 8.9 0.0 2.2 2 0 0 2 2 2 0 Protein-arginine deiminase (PAD) middle domain GARS_C PF02843.11 KKK18731.1 - 0.12 12.6 0.6 0.96 9.6 0.1 2.7 2 0 0 2 2 2 0 Phosphoribosylglycinamide synthetase, C domain CO_deh_flav_C PF03450.12 KKK18731.1 - 0.18 11.7 1.8 1.4 8.9 0.1 2.7 2 0 0 2 2 2 0 CO dehydrogenase flavoprotein C-terminal domain Pro_isomerase PF00160.16 KKK18732.1 - 2.1e-51 174.1 0.1 4.1e-51 173.2 0.1 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.27 KKK18732.1 - 2.5e-16 58.8 0.6 1.8e-05 24.4 0.0 5.3 5 0 0 5 5 5 4 WD domain, G-beta repeat Isochorismatase PF00857.15 KKK18733.1 - 4e-23 82.2 0.1 4.7e-23 81.9 0.1 1.1 1 0 0 1 1 1 1 Isochorismatase family Ank_2 PF12796.2 KKK18734.1 - 6.8e-47 157.7 0.0 7.9e-11 42.1 0.0 5.0 2 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 KKK18734.1 - 5.5e-34 114.2 12.0 0.0013 18.4 0.0 10.0 9 1 0 9 9 9 9 Ankyrin repeat Ank_4 PF13637.1 KKK18734.1 - 4.9e-27 93.7 6.8 6.2e-06 26.5 0.0 7.2 5 3 3 8 8 8 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 KKK18734.1 - 4.4e-24 83.9 9.5 2.4e-07 30.7 0.0 7.3 5 2 3 8 8 8 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 KKK18734.1 - 2.2e-22 76.8 4.5 0.0058 16.7 0.0 9.5 9 1 0 9 9 9 5 Ankyrin repeat Glyco_hydro_76 PF03663.9 KKK18735.1 - 3.9e-148 493.7 20.8 5.1e-148 493.3 14.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 AAA_13 PF13166.1 KKK18736.1 - 0.0028 16.2 2.6 0.0044 15.5 1.8 1.2 1 0 0 1 1 1 1 AAA domain 4HB_MCP_1 PF12729.2 KKK18736.1 - 0.027 13.8 7.6 0.042 13.1 5.3 1.3 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction LUC7 PF03194.10 KKK18736.1 - 0.032 13.7 4.4 0.073 12.5 3.1 1.5 1 0 0 1 1 1 0 LUC7 N_terminus IncA PF04156.9 KKK18736.1 - 9.1 5.8 13.0 0.076 12.6 3.2 1.7 2 0 0 2 2 2 0 IncA protein SNF2_N PF00176.18 KKK18759.1 - 5.7e-52 176.3 0.5 2.1e-51 174.5 0.0 2.0 2 0 0 2 2 2 1 SNF2 family N-terminal domain zf-C3HC4 PF00097.20 KKK18759.1 - 3.1e-08 33.1 8.6 7.5e-08 31.9 5.9 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KKK18759.1 - 4.8e-08 32.7 10.2 1.5e-07 31.0 7.1 2.0 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 KKK18759.1 - 2.5e-07 30.2 8.0 6.4e-07 28.9 5.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KKK18759.1 - 8.2e-06 25.7 10.8 2.2e-05 24.3 7.5 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KKK18759.1 - 0.0001 22.3 4.2 0.00035 20.6 2.9 2.0 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 KKK18759.1 - 0.00012 21.7 8.6 0.00029 20.4 5.9 1.7 1 0 0 1 1 1 1 zinc-RING finger domain Helicase_C PF00271.26 KKK18759.1 - 0.00042 20.1 0.0 0.00091 19.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Prok-RING_4 PF14447.1 KKK18759.1 - 0.0088 15.5 4.1 0.02 14.4 2.9 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.1 KKK18759.1 - 0.022 14.4 4.9 0.12 12.1 3.4 2.1 1 1 1 2 2 2 0 RING-type zinc-finger YopE PF03545.8 KKK18759.1 - 0.026 14.4 0.5 1.5 8.8 0.0 2.8 2 0 0 2 2 2 0 Yersinia virulence determinant (YopE) zf-C3HC4_4 PF15227.1 KKK18759.1 - 0.041 13.7 7.2 0.1 12.4 5.0 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING DrsE PF02635.10 KKK18759.1 - 0.14 12.1 0.0 0.39 10.7 0.0 1.7 1 0 0 1 1 1 0 DsrE/DsrF-like family Baculo_IE-1 PF05290.6 KKK18759.1 - 0.14 11.8 2.7 0.19 11.4 0.3 2.3 2 0 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) zf-P11 PF03854.9 KKK18759.1 - 0.75 9.3 8.1 2 7.9 5.6 1.7 1 0 0 1 1 1 0 P-11 zinc finger DZR PF12773.2 KKK18759.1 - 3.6 7.4 6.8 4.8 7.0 2.4 2.4 2 0 0 2 2 2 0 Double zinc ribbon Ecm29 PF13001.2 KKK18760.1 - 4.4e-159 530.1 0.0 1e-158 528.9 0.0 1.7 1 0 0 1 1 1 1 Proteasome stabiliser HEAT PF02985.17 KKK18760.1 - 0.0043 17.0 2.4 51 4.3 0.0 7.1 9 0 0 9 9 9 0 HEAT repeat Pec_lyase PF09492.5 KKK18760.1 - 0.3 10.2 0.1 3 6.9 0.0 2.4 3 0 0 3 3 3 0 Pectic acid lyase PMM PF03332.8 KKK18761.1 - 2.5e-101 337.8 0.2 3.2e-101 337.4 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase DnaJ PF00226.26 KKK18761.1 - 1.8e-17 62.7 0.1 4.2e-17 61.6 0.1 1.6 1 0 0 1 1 1 1 DnaJ domain S6PP PF05116.8 KKK18761.1 - 0.0048 16.2 0.0 1.3 8.3 0.0 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase_3 PF08282.7 KKK18761.1 - 0.0098 15.4 0.0 0.039 13.5 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase TMPIT PF07851.8 KKK18761.1 - 0.013 14.6 0.1 0.019 14.0 0.1 1.2 1 0 0 1 1 1 0 TMPIT-like protein DUF456 PF04306.8 KKK18761.1 - 0.037 14.0 0.6 0.058 13.4 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF456) Gly-zipper_OmpA PF13436.1 KKK18761.1 - 0.059 13.0 2.4 0.13 11.9 1.6 1.4 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain Bacteriocin_IIc PF10439.4 KKK18761.1 - 1 9.4 6.0 2.6 8.2 4.1 1.6 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide PNGaseA PF12222.3 KKK18762.1 - 2.9e-185 616.1 3.5 3.9e-185 615.7 2.4 1.2 1 0 0 1 1 1 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A DUF1640 PF07798.6 KKK18762.1 - 8.3e-64 214.8 6.7 1.3e-63 214.2 4.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) Metal_resist PF13801.1 KKK18762.1 - 0.36 10.8 2.6 0.8 9.6 1.8 1.6 1 0 0 1 1 1 0 Heavy-metal resistance P34-Arc PF04045.9 KKK18764.1 - 1.7e-102 341.8 0.1 2e-102 341.5 0.1 1.0 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc WD40 PF00400.27 KKK18765.1 - 1.1e-56 186.7 28.4 1.9e-08 33.8 0.2 12.1 14 0 0 14 14 14 9 WD domain, G-beta repeat Utp12 PF04003.7 KKK18765.1 - 4.3e-22 78.0 0.5 7.7e-22 77.2 0.4 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family Nup160 PF11715.3 KKK18765.1 - 4.9e-06 24.9 1.2 0.056 11.5 0.0 5.3 5 2 0 5 5 5 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 KKK18765.1 - 2.3e-05 23.3 1.8 0.33 9.6 0.1 4.0 2 1 1 3 3 3 2 Nup133 N terminal like DUF3312 PF11768.3 KKK18765.1 - 0.021 13.0 0.0 0.095 10.9 0.0 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3312) F-box PF00646.28 KKK18767.1 - 6.6e-05 22.4 0.0 0.00018 21.0 0.0 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KKK18767.1 - 0.0002 21.0 0.1 0.00049 19.7 0.0 1.7 1 0 0 1 1 1 1 F-box-like Sel1 PF08238.7 KKK18768.1 - 7e-15 55.1 12.2 7.3e-05 23.2 3.8 4.4 4 0 0 4 4 4 3 Sel1 repeat TPR_11 PF13414.1 KKK18768.1 - 0.19 11.4 4.8 16 5.2 2.4 2.7 2 1 0 2 2 2 0 TPR repeat WLM PF08325.5 KKK18769.1 - 5.8e-61 205.6 0.0 8.3e-61 205.1 0.0 1.2 1 0 0 1 1 1 1 WLM domain zf-RanBP PF00641.13 KKK18769.1 - 7.3e-05 21.7 21.3 0.00038 19.4 3.5 3.4 3 0 0 3 3 3 3 Zn-finger in Ran binding protein and others DUF45 PF01863.12 KKK18769.1 - 0.00079 19.2 2.2 0.0016 18.2 1.5 1.5 1 0 0 1 1 1 1 Protein of unknown function DUF45 SprT-like PF10263.4 KKK18769.1 - 0.00094 18.8 0.3 0.013 15.1 0.0 2.4 2 0 0 2 2 2 1 SprT-like family DZR PF12773.2 KKK18769.1 - 0.031 14.1 12.0 0.66 9.8 8.6 2.3 1 1 2 3 3 3 0 Double zinc ribbon DUF1776 PF08643.5 KKK18770.1 - 2e-105 352.2 0.0 2.4e-105 351.9 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) adh_short PF00106.20 KKK18770.1 - 0.025 14.4 0.0 0.056 13.3 0.0 1.5 2 0 0 2 2 2 0 short chain dehydrogenase Glyco_hydro_18 PF00704.23 KKK18771.1 - 2.5e-69 234.3 0.0 3e-69 234.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DUF3142 PF11340.3 KKK18771.1 - 0.011 15.4 0.0 0.014 15.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3142) DUF3712 PF12505.3 KKK18772.1 - 1.7e-33 115.3 0.7 5.1e-33 113.7 0.5 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3712) Cu-oxidase_3 PF07732.10 KKK18772.1 - 0.014 15.1 0.1 0.033 13.9 0.1 1.7 1 0 0 1 1 1 0 Multicopper oxidase Fcf1 PF04900.7 KKK18773.1 - 1.8e-11 43.9 1.1 0.00017 21.6 0.1 3.1 3 1 0 3 3 3 2 Fcf1 SpoIIE PF07228.7 KKK18774.1 - 0.0017 18.0 0.1 0.005 16.5 0.1 1.7 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.16 KKK18774.1 - 0.0041 16.5 0.0 0.0065 15.8 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C RRN3 PF05327.6 KKK18775.1 - 6.9e-191 635.1 0.0 1.8e-190 633.8 0.0 1.6 1 1 1 2 2 2 1 RNA polymerase I specific transcription initiation factor RRN3 WD40 PF00400.27 KKK18777.1 - 4.7e-27 92.8 4.9 5.5e-07 29.2 0.1 5.4 6 0 0 6 6 6 4 WD domain, G-beta repeat Nup160 PF11715.3 KKK18777.1 - 4.1e-05 21.9 0.9 0.011 13.8 0.1 2.7 2 1 0 2 2 2 2 Nucleoporin Nup120/160 Nop14 PF04147.7 KKK18777.1 - 0.99 7.2 24.9 1.8 6.3 17.3 1.3 1 0 0 1 1 1 0 Nop14-like family Astro_capsid PF03115.9 KKK18777.1 - 4.4 5.4 8.3 6.7 4.8 5.8 1.2 1 0 0 1 1 1 0 Astrovirus capsid protein precursor Cmc1 PF08583.5 KKK18778.1 - 1.5e-16 59.8 5.1 1.8e-16 59.6 3.5 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like RNA_Me_trans PF04252.8 KKK18780.1 - 1.5e-49 168.1 0.0 1.7e-49 167.9 0.0 1.0 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase bPH_5 PF10882.3 KKK18780.1 - 0.11 12.2 0.0 14 5.5 0.1 2.2 2 0 0 2 2 2 0 Bacterial PH domain Spindle_Spc25 PF08234.7 KKK18781.1 - 2.6e-22 78.5 0.4 1.1e-21 76.5 0.0 2.1 2 0 0 2 2 2 1 Chromosome segregation protein Spc25 SF-assemblin PF06705.6 KKK18781.1 - 0.017 14.2 8.3 0.024 13.8 5.8 1.1 1 0 0 1 1 1 0 SF-assemblin/beta giardin AHS1 PF02682.11 KKK18781.1 - 0.064 12.7 1.3 0.12 11.8 0.9 1.4 1 0 0 1 1 1 0 Allophanate hydrolase subunit 1 Polysacc_deac_1 PF01522.16 KKK18781.1 - 0.11 12.0 0.3 0.18 11.4 0.2 1.4 1 0 0 1 1 1 0 Polysaccharide deacetylase Mnd1 PF03962.10 KKK18781.1 - 2.6 7.6 12.3 1.5 8.4 1.4 2.1 1 1 1 2 2 2 0 Mnd1 family Rrn6 PF10214.4 KKK18782.1 - 2.5e-207 690.5 0.4 2.9e-207 690.3 0.3 1.0 1 0 0 1 1 1 1 RNA polymerase I-specific transcription-initiation factor WD40 PF00400.27 KKK18784.1 - 8.5e-47 155.4 11.5 1.6e-09 37.2 0.0 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat Apc4_WD40 PF12894.2 KKK18784.1 - 0.00076 18.9 0.0 9.9 5.7 0.0 4.1 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.9 KKK18784.1 - 0.069 11.9 0.1 0.27 10.0 0.1 1.7 2 0 0 2 2 2 0 Coatomer WD associated region Mito_fiss_reg PF05308.6 KKK18784.1 - 1.6 8.0 4.0 2.6 7.3 2.8 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator Tcp11 PF05794.8 KKK18785.1 - 4.5e-41 140.9 0.0 5.3e-40 137.4 0.0 2.5 1 1 0 1 1 1 1 T-complex protein 11 PIN_4 PF13638.1 KKK18785.1 - 5.1 7.1 7.9 45 4.1 0.0 3.0 2 1 0 2 2 2 0 PIN domain zinc_ribbon_6 PF14599.1 KKK18786.1 - 3.3e-25 87.6 0.4 3.3e-25 87.6 0.2 3.5 3 0 0 3 3 3 1 Zinc-ribbon zf-CHY PF05495.7 KKK18786.1 - 1.2e-15 57.4 21.0 1.2e-15 57.4 14.5 4.4 3 1 1 4 4 4 1 CHY zinc finger zf-RING_2 PF13639.1 KKK18786.1 - 2.3e-09 36.9 9.1 2.3e-09 36.9 6.3 3.9 3 1 0 3 3 3 1 Ring finger domain zf-C3HC4_3 PF13920.1 KKK18786.1 - 4.7e-08 32.5 6.9 4.7e-08 32.5 4.8 5.9 3 2 2 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KKK18786.1 - 2.1e-07 30.8 6.4 2.1e-07 30.8 4.4 5.5 4 2 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KKK18786.1 - 7.7e-06 25.5 6.9 7.7e-06 25.5 4.8 6.0 4 1 1 5 5 5 1 zinc-RING finger domain Nop14 PF04147.7 KKK18786.1 - 7.4 4.3 17.8 10 3.8 12.3 1.1 1 0 0 1 1 1 0 Nop14-like family Endosulfine PF04667.12 KKK18787.1 - 3.8e-22 78.0 0.0 5.6e-22 77.5 0.0 1.3 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region Peptidase_S10 PF00450.17 KKK18788.1 - 2.6e-115 385.8 0.0 3.2e-115 385.6 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 KKK18788.1 - 0.00023 21.0 0.0 0.00058 19.8 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Myc_target_1 PF15179.1 KKK18788.1 - 0.018 14.6 0.2 0.032 13.8 0.1 1.3 1 0 0 1 1 1 0 Myc target protein 1 Act-Frag_cataly PF09192.5 KKK18788.1 - 0.14 11.0 0.0 0.23 10.3 0.0 1.2 1 0 0 1 1 1 0 Actin-fragmin kinase, catalytic SKG6 PF08693.5 KKK18788.1 - 9.3 5.6 7.2 17 4.8 5.0 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Zn_clus PF00172.13 KKK18794.1 - 2.9e-06 27.0 12.6 5e-06 26.3 8.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ASFV_360 PF01671.11 KKK18794.1 - 0.035 13.4 0.0 0.056 12.8 0.0 1.2 1 0 0 1 1 1 0 African swine fever virus multigene family 360 protein Chitin_synth_2 PF03142.10 KKK18817.1 - 1.5e-257 855.2 2.2 2e-257 854.7 1.6 1.2 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.16 KKK18817.1 - 2.8e-195 650.3 0.0 3.8e-195 649.9 0.0 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) DEK_C PF08766.6 KKK18817.1 - 2.3e-19 68.8 0.9 3.8e-18 64.9 0.5 2.6 2 0 0 2 2 2 1 DEK C terminal domain Cyt-b5 PF00173.23 KKK18817.1 - 4.5e-17 61.6 0.0 1.3e-12 47.3 0.0 2.8 1 1 1 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_tranf_2_3 PF13641.1 KKK18817.1 - 2.9e-14 53.4 0.1 1.1e-11 44.9 0.0 2.5 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 KKK18817.1 - 3.3e-12 46.5 4.9 3.3e-12 46.5 3.4 2.6 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.1 KKK18817.1 - 0.00061 19.1 0.0 0.0025 17.1 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 KKK18817.1 - 0.0011 18.7 0.0 0.013 15.2 0.0 2.5 2 0 0 2 2 2 1 Glycosyl transferase family 2 AAA_16 PF13191.1 KKK18817.1 - 0.034 14.1 0.1 0.086 12.8 0.1 1.6 1 0 0 1 1 1 0 AAA ATPase domain DUF258 PF03193.11 KKK18817.1 - 0.045 12.9 0.0 0.11 11.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_22 PF13401.1 KKK18817.1 - 0.077 13.1 0.0 0.24 11.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain Dynactin PF12455.3 KKK18818.1 - 4e-96 321.1 7.8 4e-96 321.1 5.4 3.4 3 1 1 4 4 4 1 Dynein associated protein CAP_GLY PF01302.20 KKK18818.1 - 8.8e-23 79.8 0.1 1.5e-22 79.0 0.1 1.4 1 0 0 1 1 1 1 CAP-Gly domain UCH PF00443.24 KKK18819.1 - 1.2e-68 231.1 0.0 8.5e-68 228.3 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.7 KKK18819.1 - 1.4e-15 57.4 0.0 5.4e-15 55.6 0.0 2.1 1 0 0 1 1 1 1 DUSP domain UCH_1 PF13423.1 KKK18819.1 - 4e-13 49.4 0.0 1.8e-06 27.6 0.0 2.5 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase USP7_C2 PF14533.1 KKK18819.1 - 0.0021 17.5 0.1 0.005 16.2 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin-specific protease C-terminal zf-C2H2_4 PF13894.1 KKK18843.1 - 0.022 15.0 1.8 0.067 13.5 1.2 1.9 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2 PF00096.21 KKK18843.1 - 0.28 11.6 3.0 0.65 10.4 2.1 1.7 1 0 0 1 1 1 0 Zinc finger, C2H2 type DUF1387 PF07139.6 KKK18854.1 - 0.24 10.9 3.3 0.26 10.8 2.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) GAGA_bind PF06217.7 KKK18854.1 - 0.72 9.7 4.4 0.74 9.7 3.0 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family AlaDh_PNT_N PF05222.10 KKK18855.1 - 3.4e-30 104.8 0.0 5.4e-30 104.1 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.16 KKK18855.1 - 3e-19 69.2 0.0 4.4e-19 68.6 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.14 KKK18855.1 - 0.075 12.1 0.0 0.15 11.2 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain RCC1 PF00415.13 KKK18856.1 - 2.3e-38 130.1 10.6 7.4e-09 35.6 0.2 7.7 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 KKK18856.1 - 9.4e-29 98.3 34.3 1.8e-09 36.9 0.5 7.7 8 0 0 8 8 8 5 Regulator of chromosome condensation (RCC1) repeat CBM_X PF06204.6 KKK18856.1 - 0.0023 17.3 4.5 16 5.0 0.0 5.4 6 0 0 6 6 6 1 Putative carbohydrate binding domain Porin_3 PF01459.17 KKK18856.1 - 0.065 12.5 7.4 0.23 10.7 0.4 2.3 1 1 1 2 2 2 0 Eukaryotic porin DUF481 PF04338.7 KKK18856.1 - 5.7 6.5 8.4 13 5.4 0.8 2.1 1 1 1 2 2 2 0 Protein of unknown function, DUF481 UCH PF00443.24 KKK18857.1 - 5.5e-41 140.4 0.0 4.4e-35 121.1 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KKK18857.1 - 8e-13 48.4 0.4 5.3e-12 45.7 0.2 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Oxysterol_BP PF01237.13 KKK18858.1 - 2.9e-87 292.4 0.1 4.4e-87 291.8 0.1 1.2 1 0 0 1 1 1 1 Oxysterol-binding protein F_bP_aldolase PF01116.15 KKK18859.1 - 2.4e-97 325.4 0.0 2.8e-97 325.3 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II RSN1_TM PF13967.1 KKK18860.1 - 5.3e-41 139.8 2.2 6.6e-41 139.4 1.5 1.1 1 0 0 1 1 1 1 Late exocytosis, associated with Golgi transport DUF3445 PF11927.3 KKK18862.1 - 6.9e-06 25.6 0.0 8.5e-06 25.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) DUF221 PF02714.10 KKK18863.1 - 2.4e-98 328.9 21.2 3e-98 328.6 14.7 1.1 1 0 0 1 1 1 1 Domain of unknown function DUF221 DUF4463 PF14703.1 KKK18863.1 - 3.1e-18 66.0 0.3 9e-18 64.5 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4463) Dockerin_1 PF00404.13 KKK18863.1 - 0.088 12.5 0.2 0.088 12.5 0.1 2.5 2 0 0 2 2 2 0 Dockerin type I repeat LRR19-TM PF15176.1 KKK18863.1 - 2 8.1 4.0 1.1 8.9 0.3 2.5 3 0 0 3 3 3 0 Leucine-rich repeat family 19 TM domain DUF4078 PF13300.1 KKK18864.1 - 4e-29 100.5 16.1 4e-29 100.5 11.2 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4078) Homoserine_dh PF00742.14 KKK18865.1 - 1e-51 175.1 0.0 1.3e-51 174.8 0.0 1.1 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.11 KKK18865.1 - 1.7e-12 47.7 0.0 3.6e-12 46.7 0.0 1.6 1 1 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain F420_oxidored PF03807.12 KKK18865.1 - 0.099 13.0 0.0 0.2 12.0 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DnaJ PF00226.26 KKK18866.1 - 0.021 14.5 0.3 0.054 13.2 0.1 1.7 2 0 0 2 2 2 0 DnaJ domain HMG_box PF00505.14 KKK18868.1 - 4.5e-26 90.9 1.1 6.3e-26 90.4 0.8 1.2 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KKK18868.1 - 3.7e-20 72.0 1.6 5.5e-20 71.5 1.1 1.2 1 0 0 1 1 1 1 HMG-box domain HMG_box_5 PF14887.1 KKK18868.1 - 0.002 17.8 0.9 0.004 16.9 0.6 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box 5 DUF1014 PF06244.7 KKK18868.1 - 0.011 15.9 0.2 0.035 14.3 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1014) CENP-H PF05837.7 KKK18869.1 - 5.9e-35 119.6 13.2 7e-35 119.4 3.4 2.1 2 0 0 2 2 2 2 Centromere protein H (CENP-H) DUF2599 PF10783.4 KKK18869.1 - 0.048 14.2 0.3 0.11 13.1 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2599) DUF4332 PF14229.1 KKK18869.1 - 0.11 12.4 4.8 0.1 12.5 1.5 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4332) DivIC PF04977.10 KKK18869.1 - 0.57 9.6 15.6 1.3 8.5 0.5 3.2 3 0 0 3 3 3 0 Septum formation initiator TBPIP PF07106.8 KKK18869.1 - 1.2 8.6 9.3 0.069 12.6 0.8 2.0 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) NusB PF01029.13 KKK18869.1 - 4.8 7.1 8.8 0.52 10.2 2.0 2.0 2 1 0 2 2 2 0 NusB family ATG11 PF10377.4 KKK18870.1 - 1.4e-40 138.1 0.0 1.4e-40 138.1 0.0 3.1 3 0 0 3 3 3 1 Autophagy-related protein 11 APG17 PF04108.7 KKK18870.1 - 2.9e-07 29.6 0.2 2.9e-07 29.6 0.1 4.7 3 1 1 4 4 4 1 Autophagy protein Apg17 CENP-Q PF13094.1 KKK18870.1 - 0.0092 16.0 8.9 0.0092 16.0 6.2 6.2 2 1 4 6 6 6 1 CENP-Q, a CENPA-CAD centromere complex subunit WEMBL PF05701.6 KKK18870.1 - 0.61 8.4 67.3 0.12 10.8 19.8 2.8 3 0 0 3 3 3 0 Weak chloroplast movement under blue light Pox_A_type_inc PF04508.7 KKK18870.1 - 3.1 7.8 24.9 0.22 11.3 0.1 6.9 6 0 0 6 6 6 0 Viral A-type inclusion protein repeat Abhydrolase_3 PF07859.8 KKK18873.1 - 4e-40 137.6 0.0 6.3e-39 133.7 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 KKK18873.1 - 1.3e-06 27.2 0.0 1.1e-05 24.2 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 KKK18873.1 - 0.0033 17.1 0.0 0.0052 16.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Pterin_4a PF01329.14 KKK18873.1 - 0.031 14.0 0.2 0.72 9.6 0.1 2.2 2 0 0 2 2 2 0 Pterin 4 alpha carbinolamine dehydratase FHA PF00498.21 KKK18874.1 - 1.1e-11 44.6 0.0 2.2e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 FHA domain Glycos_transf_1 PF00534.15 KKK18881.1 - 2.2e-15 56.4 0.0 8.5e-15 54.5 0.0 1.9 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 KKK18881.1 - 4.7e-09 36.5 0.0 2.4e-08 34.2 0.0 2.2 3 0 0 3 3 3 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 KKK18881.1 - 4e-05 23.8 0.0 8.3e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 DUF3646 PF12362.3 KKK18881.1 - 0.013 15.3 0.0 0.04 13.8 0.0 1.7 2 0 0 2 2 2 0 DNA polymerase III gamma and tau subunits C terminal Rpn3_C PF08375.6 KKK18926.1 - 1.3e-24 86.3 0.4 5.4e-24 84.3 0.2 2.1 1 0 0 1 1 1 1 Proteasome regulatory subunit C-terminal PCI PF01399.22 KKK18926.1 - 2.1e-19 69.7 0.9 1.2e-18 67.3 0.0 2.5 3 0 0 3 3 3 1 PCI domain PCI_Csn8 PF10075.4 KKK18926.1 - 0.0019 17.9 1.0 0.02 14.6 0.2 2.5 2 1 0 2 2 2 1 COP9 signalosome, subunit CSN8 polyprenyl_synt PF00348.12 KKK18927.1 - 4.2e-50 170.0 0.0 4.2e-48 163.4 0.0 2.2 2 0 0 2 2 2 2 Polyprenyl synthetase DUF2404 PF10296.4 KKK18927.1 - 5.6e-30 103.3 0.0 1.2e-29 102.2 0.0 1.6 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) UPF0449 PF15136.1 KKK18927.1 - 0.076 13.2 0.1 20 5.4 0.0 3.0 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 HEPPP_synt_1 PF07307.6 KKK18927.1 - 0.16 11.3 0.0 0.35 10.3 0.0 1.5 1 0 0 1 1 1 0 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 TFIID_20kDa PF03847.8 KKK18928.1 - 1.4e-21 76.5 0.0 2.9e-21 75.5 0.0 1.6 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Histone PF00125.19 KKK18928.1 - 0.016 15.2 0.0 0.047 13.8 0.0 1.8 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 DASH_Spc34 PF08657.5 KKK18929.1 - 5.9e-68 229.3 9.8 1.4e-66 224.7 6.8 2.0 1 1 0 1 1 1 1 DASH complex subunit Spc34 REV PF00424.13 KKK18929.1 - 0.0011 18.7 0.1 0.016 15.0 0.2 2.2 2 0 0 2 2 2 1 REV protein (anti-repression trans-activator protein) DUF3866 PF12982.2 KKK18929.1 - 0.0067 15.4 0.0 0.012 14.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3866) IncA PF04156.9 KKK18929.1 - 0.032 13.8 3.8 0.054 13.0 2.6 1.6 1 1 0 1 1 1 0 IncA protein CENP-F_leu_zip PF10473.4 KKK18929.1 - 0.036 13.9 2.7 0.37 10.6 0.2 2.5 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ISG65-75 PF11727.3 KKK18929.1 - 0.24 10.4 2.5 0.17 10.9 0.4 1.6 1 1 0 1 1 1 0 Invariant surface glycoprotein DUF465 PF04325.8 KKK18929.1 - 0.24 11.1 2.1 0.37 10.5 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF465) TMF_DNA_bd PF12329.3 KKK18929.1 - 0.36 10.6 6.4 4.9 7.0 0.1 2.7 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding Sipho_Gp157 PF05565.6 KKK18929.1 - 2.1 7.9 5.3 0.98 8.9 1.3 2.1 2 1 0 2 2 2 0 Siphovirus Gp157 Thg1C PF14413.1 KKK18930.1 - 1.4e-54 182.9 1.1 2e-54 182.4 0.8 1.2 1 0 0 1 1 1 1 Thg1 C terminal domain Thg1 PF04446.7 KKK18930.1 - 6.8e-47 158.4 0.0 1e-46 157.9 0.0 1.3 1 0 0 1 1 1 1 tRNAHis guanylyltransferase DUF1319 PF07028.6 KKK18930.1 - 0.05 13.8 0.1 0.086 13.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1319) DDE_Tnp_1 PF01609.16 KKK18931.1 - 8.1 5.9 15.1 0.18 11.3 1.2 2.2 2 0 0 2 2 2 0 Transposase DDE domain Cmc1 PF08583.5 KKK18932.1 - 5.7e-15 54.8 7.2 1.6e-14 53.3 5.0 1.8 1 1 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like NDUF_B7 PF05676.8 KKK18932.1 - 0.048 13.0 0.8 0.048 13.0 0.5 1.6 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) DUF3287 PF11690.3 KKK18932.1 - 0.58 10.2 4.1 1 9.4 2.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3287) WD40 PF00400.27 KKK18933.1 - 5.3e-15 54.6 0.3 0.0011 18.7 0.0 4.7 5 0 0 5 5 5 3 WD domain, G-beta repeat Nup160 PF11715.3 KKK18933.1 - 0.0046 15.1 0.1 0.11 10.6 0.0 2.6 2 1 1 3 3 3 1 Nucleoporin Nup120/160 TFIID-31kDa PF02291.10 KKK18934.1 - 5.8e-30 103.7 0.0 7.7e-24 83.9 0.0 2.9 1 1 1 2 2 2 2 Transcription initiation factor IID, 31kD subunit CPSF100_C PF13299.1 KKK18934.1 - 1.7 8.7 5.5 2.4 8.2 0.0 2.6 3 0 0 3 3 3 0 Cleavage and polyadenylation factor 2 C-terminal Dicty_REP PF05086.7 KKK18934.1 - 3.6 5.2 7.8 7.6 4.1 5.4 1.5 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein SSP160 PF06933.6 KKK18934.1 - 6.1 4.7 25.3 8.4 4.2 17.5 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 LNS2 PF08235.8 KKK18935.1 - 8.5e-71 236.6 0.0 1.5e-70 235.8 0.0 1.4 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.9 KKK18935.1 - 5.4e-41 138.7 0.0 2.6e-40 136.4 0.0 2.0 2 0 0 2 2 2 1 lipin, N-terminal conserved region Acid_phosphat_B PF03767.9 KKK18935.1 - 0.0023 17.3 0.0 0.22 10.8 0.0 2.8 3 0 0 3 3 3 1 HAD superfamily, subfamily IIIB (Acid phosphatase) AF1Q PF15017.1 KKK18935.1 - 0.45 10.4 8.0 1.1 9.2 5.5 1.6 1 0 0 1 1 1 0 Drug resistance and apoptosis regulator fn3 PF00041.16 KKK18936.1 - 3.4e-06 27.1 0.0 9e-06 25.7 0.0 1.8 1 0 0 1 1 1 1 Fibronectin type III domain APH PF01636.18 KKK18937.1 - 4.7e-09 36.3 0.0 1.1e-08 35.1 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.6 KKK18937.1 - 0.0098 14.5 0.0 0.018 13.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) zf-H2C2_2 PF13465.1 KKK18952.1 - 4.3e-11 42.5 14.3 6.2e-06 26.2 0.2 3.5 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 KKK18952.1 - 2.5e-09 36.9 13.9 1.9e-05 24.7 3.1 2.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KKK18952.1 - 2.9e-07 30.3 8.3 0.0002 21.4 1.6 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.2 KKK18952.1 - 6.1e-06 26.2 1.5 1.9e-05 24.6 1.0 1.9 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KKK18952.1 - 5.8e-05 23.1 5.7 0.00012 22.1 1.4 2.5 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 KKK18952.1 - 0.00036 20.3 7.5 0.0039 17.0 1.1 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_2 PF12756.2 KKK18952.1 - 0.061 13.4 1.1 0.061 13.4 0.7 1.5 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2HC_2 PF13913.1 KKK18952.1 - 0.58 9.8 3.8 5.8 6.7 0.2 2.3 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-BED PF02892.10 KKK18952.1 - 0.68 9.7 5.1 0.26 11.0 0.5 2.2 2 0 0 2 2 2 0 BED zinc finger zf-H2C2_5 PF13909.1 KKK18952.1 - 4.9 7.5 8.7 6.4 7.2 1.2 3.2 2 1 1 3 3 3 0 C2H2-type zinc-finger domain Acyl_transf_1 PF00698.16 KKK18959.1 - 3.2e-82 276.3 0.0 4.7e-81 272.5 0.0 2.4 2 0 0 2 2 2 1 Acyl transferase domain MaoC_dehydratas PF01575.14 KKK18959.1 - 1e-39 134.7 0.0 2.8e-39 133.3 0.0 1.8 1 0 0 1 1 1 1 MaoC like domain DUF1729 PF08354.5 KKK18959.1 - 2.1e-30 104.2 0.1 5.8e-30 102.8 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) MaoC_dehydrat_N PF13452.1 KKK18959.1 - 1.9e-20 72.9 0.1 9.2e-20 70.7 0.0 2.2 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase NMO PF03060.10 KKK18959.1 - 0.031 13.4 0.5 0.41 9.7 0.2 2.3 2 0 0 2 2 2 0 Nitronate monooxygenase PAS_9 PF13426.1 KKK18966.1 - 4.1e-30 104.2 0.0 1.3e-17 64.1 0.0 3.4 3 0 0 3 3 3 3 PAS domain PAS_3 PF08447.6 KKK18966.1 - 7.9e-19 67.5 0.0 8.7e-10 38.5 0.0 3.6 3 0 0 3 3 3 3 PAS fold PAS PF00989.19 KKK18966.1 - 4.3e-14 52.2 0.0 0.00011 21.9 0.0 3.6 3 0 0 3 3 3 3 PAS fold GATA PF00320.22 KKK18966.1 - 7.2e-14 50.8 5.4 7.2e-14 50.8 3.8 1.9 2 0 0 2 2 2 1 GATA zinc finger PAS_11 PF14598.1 KKK18966.1 - 2.4e-12 46.8 0.1 1.6e-06 28.0 0.0 3.3 3 0 0 3 3 3 2 PAS domain PAS_4 PF08448.5 KKK18966.1 - 1.5e-10 41.1 0.0 0.046 13.7 0.0 3.6 3 0 0 3 3 3 3 PAS fold PAS_8 PF13188.1 KKK18966.1 - 0.006 16.3 0.0 0.057 13.3 0.0 2.4 2 0 0 2 2 2 1 PAS domain PAS_2 PF08446.6 KKK18966.1 - 0.16 12.4 0.0 2.3 8.7 0.0 2.4 2 0 0 2 2 2 0 PAS fold Kinetocho_Slk19 PF12709.2 KKK18966.1 - 0.24 11.5 1.4 0.45 10.6 1.0 1.3 1 0 0 1 1 1 0 Central kinetochore-associated Histone PF00125.19 KKK18978.1 - 4.2e-22 78.0 0.0 5.5e-22 77.6 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KKK18978.1 - 4.8e-05 23.3 0.0 6.9e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone R3H PF01424.17 KKK18979.1 - 2.4e-11 43.1 0.0 5.4e-11 42.0 0.0 1.7 1 0 0 1 1 1 1 R3H domain SUZ-C PF12901.2 KKK18979.1 - 5.9e-07 28.9 5.0 2.4e-06 27.0 3.5 2.2 1 0 0 1 1 1 1 SUZ-C motif RRM_6 PF14259.1 KKK18979.1 - 9.3e-07 28.7 0.0 1.6e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KKK18979.1 - 5.3e-06 25.9 0.1 9.9e-06 25.1 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KKK18979.1 - 0.0063 16.3 0.0 0.013 15.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Gp_dh_C PF02800.15 KKK18980.1 - 4.1e-76 253.7 0.1 6.3e-76 253.1 0.0 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 KKK18980.1 - 4e-59 198.9 0.1 7.1e-59 198.1 0.0 1.4 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 KKK18980.1 - 0.036 13.2 0.1 0.23 10.5 0.0 2.0 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N PF00107.21 KKK18980.1 - 0.078 12.5 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Pho88 PF10032.4 KKK18981.1 - 1.4e-78 262.5 0.1 1.7e-78 262.2 0.0 1.1 1 0 0 1 1 1 1 Phosphate transport (Pho88) Abhydrolase_3 PF07859.8 KKK18983.1 - 6.4e-21 74.9 0.0 8.2e-21 74.5 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 KKK18983.1 - 2.4e-19 69.2 0.0 7.7e-19 67.5 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_6 PF12697.2 KKK18983.1 - 1.2e-06 28.5 0.0 3.4e-06 27.1 0.0 1.7 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KKK18983.1 - 6.3e-06 26.0 0.0 8.9e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2974 PF11187.3 KKK18983.1 - 0.0034 16.7 0.0 0.0054 16.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Peptidase_S9 PF00326.16 KKK18983.1 - 0.017 14.3 0.0 0.69 9.0 0.0 2.4 2 0 0 2 2 2 0 Prolyl oligopeptidase family DUF2305 PF10230.4 KKK18983.1 - 0.11 11.8 0.0 0.22 10.9 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) DctM PF06808.7 KKK18984.1 - 0.041 12.4 0.4 0.06 11.8 0.3 1.2 1 0 0 1 1 1 0 DctM-like transporters TroA PF01297.12 KKK18985.1 - 0.085 12.0 11.5 0.006 15.8 1.6 3.1 3 0 0 3 3 3 0 Periplasmic solute binding protein family Cellulase PF00150.13 KKK18986.1 - 8.2e-07 28.4 1.5 1.4e-06 27.7 0.0 1.9 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) TMEM154 PF15102.1 KKK18986.1 - 0.0007 19.3 0.3 0.002 17.8 0.0 1.8 2 0 0 2 2 2 1 TMEM154 protein family DUF3357 PF11837.3 KKK18986.1 - 0.0013 18.5 0.3 0.011 15.5 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3357) DUF1191 PF06697.7 KKK18986.1 - 0.0043 15.9 0.0 0.0077 15.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1191) EphA2_TM PF14575.1 KKK18986.1 - 0.024 15.0 1.4 0.05 14.0 0.0 2.2 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF1510 PF07423.6 KKK18986.1 - 0.046 13.0 0.1 0.046 13.0 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1510) Wzy_C PF04932.10 KKK18986.1 - 0.05 13.3 0.0 0.09 12.5 0.0 1.3 1 0 0 1 1 1 0 O-Antigen ligase Tetraspannin PF00335.15 KKK18986.1 - 0.057 12.6 0.7 0.095 11.9 0.0 1.6 2 0 0 2 2 2 0 Tetraspanin family CcmH PF03918.9 KKK18986.1 - 0.13 11.2 0.0 0.74 8.7 0.0 2.2 2 0 0 2 2 2 0 Cytochrome C biogenesis protein Ribonuc_L-PSP PF01042.16 KKK18987.1 - 2.5e-22 78.9 0.0 3.1e-22 78.5 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP Mid2 PF04478.7 KKK18988.1 - 0.00095 18.6 1.1 0.0018 17.6 0.8 1.4 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor Dicty_REP PF05086.7 KKK18988.1 - 0.0012 16.7 0.2 0.0015 16.4 0.1 1.1 1 0 0 1 1 1 1 Dictyostelium (Slime Mold) REP protein Alpha_GJ PF03229.8 KKK18988.1 - 0.0089 16.3 2.6 0.0089 16.3 1.8 1.8 2 0 0 2 2 2 1 Alphavirus glycoprotein J Tox-GHH PF15636.1 KKK18988.1 - 0.011 15.3 0.1 0.027 14.1 0.1 1.6 1 0 0 1 1 1 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin Mucin PF01456.12 KKK18988.1 - 0.022 14.5 23.1 0.044 13.5 14.0 2.1 2 0 0 2 2 2 0 Mucin-like glycoprotein TMEM154 PF15102.1 KKK18988.1 - 0.03 14.0 1.4 0.053 13.2 1.0 1.5 1 0 0 1 1 1 0 TMEM154 protein family SSP160 PF06933.6 KKK18988.1 - 0.044 11.7 16.3 0.078 10.9 11.3 1.4 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Gly_transf_sug PF04488.10 KKK18989.1 - 3.1e-10 40.3 0.0 5.5e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.7 KKK18989.1 - 0.00072 18.7 0.0 0.0011 18.1 0.0 1.2 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein DUF3246 PF11596.3 KKK18989.1 - 0.0029 16.9 6.0 0.0049 16.1 4.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3246) TcdA_TcdB PF12919.2 KKK18989.1 - 0.093 11.2 0.0 1.3 7.4 0.0 2.3 3 0 0 3 3 3 0 TcdA/TcdB catalytic glycosyltransferase domain SNF2_N PF00176.18 KKK18990.1 - 1.4e-73 247.3 0.0 2.3e-73 246.6 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KKK18990.1 - 2.8e-11 43.1 0.0 7.9e-11 41.6 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Pkinase PF00069.20 KKK18991.1 - 1.1e-57 195.1 0.0 1.5e-57 194.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK18991.1 - 1.9e-30 105.7 0.0 2.6e-30 105.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KKK18991.1 - 1.7e-05 23.9 0.0 2.8e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KKK18991.1 - 0.01 14.8 0.0 0.019 14.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KKK18991.1 - 0.011 15.5 0.2 0.011 15.5 0.1 2.3 2 1 1 3 3 3 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 KKK18991.1 - 0.11 11.3 0.1 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 DUF605 PF04652.11 KKK18991.1 - 6.1 6.1 11.7 8.2 5.7 8.1 1.1 1 0 0 1 1 1 0 Vta1 like bZIP_1 PF00170.16 KKK18992.1 - 0.0015 18.4 11.4 0.003 17.4 6.7 2.1 1 1 1 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 KKK18992.1 - 0.17 11.6 9.3 0.092 12.5 4.3 2.0 2 0 0 2 2 2 0 Basic region leucine zipper eIF-3_zeta PF05091.7 KKK18993.1 - 4.4e-197 655.7 0.0 5.1e-197 655.5 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Pkinase PF00069.20 KKK18994.1 - 2.6e-27 95.6 0.0 3.5e-27 95.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK18994.1 - 1.9e-22 79.5 0.0 2.7e-22 79.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KKK18994.1 - 0.00019 20.5 0.0 0.00033 19.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KKK18994.1 - 0.00041 19.4 0.0 0.0011 18.0 0.0 1.6 1 1 0 1 1 1 1 Kinase-like RIO1 PF01163.17 KKK18994.1 - 0.031 13.6 0.0 0.048 13.0 0.0 1.2 1 0 0 1 1 1 0 RIO1 family WaaY PF06176.6 KKK18994.1 - 0.047 12.9 0.0 0.069 12.3 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) APH PF01636.18 KKK18994.1 - 0.05 13.3 0.0 0.082 12.6 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family PIP49_C PF12260.3 KKK18994.1 - 0.057 12.8 0.0 0.18 11.2 0.0 1.8 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 Choline_kinase PF01633.15 KKK18994.1 - 0.064 12.8 0.2 0.13 11.8 0.2 1.5 1 1 0 1 1 1 0 Choline/ethanolamine kinase Ribosomal_L33 PF00471.15 KKK18997.1 - 0.0003 20.9 0.0 0.0004 20.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L33 ADH_zinc_N_2 PF13602.1 KKK18998.1 - 2.8e-24 86.4 0.0 5e-24 85.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 KKK18998.1 - 2.5e-17 62.6 0.0 4.4e-17 61.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KKK18998.1 - 3.3e-05 23.5 0.2 0.00083 19.0 0.0 2.3 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Sugar_tr PF00083.19 KKK18999.1 - 5e-30 104.4 24.3 2.4e-18 65.9 5.6 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 KKK18999.1 - 4.2e-18 65.1 38.8 1e-10 40.9 7.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily ParA PF10609.4 KKK19000.1 - 1.7e-31 107.9 0.0 3.7e-31 106.8 0.0 1.6 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 KKK19000.1 - 2.5e-17 62.9 0.0 3.7e-17 62.3 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 KKK19000.1 - 2.9e-09 37.0 0.0 7.7e-09 35.6 0.0 1.7 2 0 0 2 2 2 1 AAA domain MipZ PF09140.6 KKK19000.1 - 2.4e-05 23.5 0.0 3.7e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.10 KKK19000.1 - 0.0013 17.8 0.2 0.0054 15.8 0.3 1.8 2 0 0 2 2 2 1 Anion-transporting ATPase AAA_25 PF13481.1 KKK19000.1 - 0.009 15.4 0.0 0.027 13.8 0.0 1.8 2 0 0 2 2 2 1 AAA domain Fer4_NifH PF00142.13 KKK19000.1 - 0.06 12.5 0.0 0.9 8.6 0.0 2.0 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family DUF1610 PF07754.6 KKK19000.1 - 9.7 6.4 7.2 6.3 7.0 0.6 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF1610) Abhydrolase_3 PF07859.8 KKK19001.1 - 2.9e-31 108.6 0.0 1.3e-24 87.0 0.1 3.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold DUF2424 PF10340.4 KKK19001.1 - 6.1e-16 58.0 0.0 9.3e-16 57.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) COesterase PF00135.23 KKK19001.1 - 0.013 14.2 0.1 0.29 9.7 0.0 2.1 2 0 0 2 2 2 0 Carboxylesterase family AATF-Che1 PF13339.1 KKK19003.1 - 1.5e-31 109.2 3.1 1.5e-31 109.2 2.1 3.4 2 1 0 3 3 3 1 Apoptosis antagonizing transcription factor TRAUB PF08164.7 KKK19003.1 - 2e-31 107.9 0.1 2e-31 107.9 0.1 2.1 2 0 0 2 2 2 1 Apoptosis-antagonizing transcription factor, C-terminal BCS1_N PF08740.6 KKK19004.1 - 5.5e-56 189.1 0.1 5.5e-56 189.1 0.0 1.8 2 0 0 2 2 2 1 BCS1 N terminal AAA PF00004.24 KKK19004.1 - 1.7e-15 57.4 0.0 3.8e-07 30.3 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KKK19004.1 - 0.0022 18.7 0.1 0.012 16.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.8 KKK19004.1 - 0.01 14.7 0.0 0.021 13.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_25 PF13481.1 KKK19004.1 - 0.021 14.2 0.0 0.046 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 KKK19004.1 - 0.022 14.5 0.0 0.055 13.2 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_18 PF13238.1 KKK19004.1 - 0.036 14.3 0.0 0.17 12.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain KaiC PF06745.8 KKK19004.1 - 0.038 13.1 0.0 0.065 12.3 0.0 1.3 1 0 0 1 1 1 0 KaiC AAA_16 PF13191.1 KKK19004.1 - 0.049 13.6 0.0 0.12 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.9 KKK19004.1 - 0.064 12.9 0.0 0.19 11.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_11 PF13086.1 KKK19004.1 - 0.46 10.0 5.4 6 6.3 3.7 2.2 1 1 0 1 1 1 0 AAA domain Phosphodiest PF01663.17 KKK19005.1 - 1.1e-83 281.5 0.1 1.6e-83 281.0 0.1 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 KKK19005.1 - 0.0018 17.5 0.1 1.3 8.1 0.0 2.2 1 1 1 2 2 2 2 Sulfatase PglZ PF08665.7 KKK19005.1 - 0.0085 15.7 0.1 0.67 9.5 0.0 2.8 3 0 0 3 3 3 1 PglZ domain DUF229 PF02995.12 KKK19005.1 - 0.16 10.3 0.0 0.24 9.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF229) CBFB_NFYA PF02045.10 KKK19008.1 - 1.2e-30 105.8 4.1 2.3e-30 104.8 2.9 1.5 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B Hus1 PF04005.7 KKK19008.1 - 0.085 11.7 0.4 0.17 10.8 0.1 1.5 1 1 0 1 1 1 0 Hus1-like protein Kinesin PF00225.18 KKK19009.1 - 4.8e-112 373.9 0.0 7.3e-112 373.3 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain DUF3694 PF12473.3 KKK19009.1 - 4.3e-43 146.3 0.1 1e-42 145.1 0.1 1.7 1 0 0 1 1 1 1 Kinesin protein PH PF00169.24 KKK19009.1 - 1.1e-08 35.2 0.0 3.4e-08 33.6 0.0 1.9 2 0 0 2 2 2 1 PH domain KIF1B PF12423.3 KKK19009.1 - 6.9e-08 32.3 0.3 2e-07 30.9 0.2 1.9 1 0 0 1 1 1 1 Kinesin protein 1B FHA PF00498.21 KKK19009.1 - 3.3e-05 23.8 0.8 0.00074 19.5 0.0 3.5 4 0 0 4 4 4 1 FHA domain Glyco_transf_90 PF05686.7 KKK19010.1 - 1.9e-28 99.2 0.0 3e-28 98.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 90 Glyco_trans_1_2 PF13524.1 KKK19010.1 - 8.5e-05 22.7 0.0 0.00015 21.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_hydro_43 PF04616.9 KKK19011.1 - 1.3e-33 116.2 0.0 1.7e-33 115.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Glyco_hydro_32N PF00251.15 KKK19011.1 - 0.074 12.3 0.1 0.19 11.0 0.0 1.7 2 1 0 2 2 2 0 Glycosyl hydrolases family 32 N-terminal domain Trypan_PARP PF05887.6 KKK19012.1 - 3.9 7.2 24.8 0.035 13.9 1.8 2.5 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) DUF3546 PF12066.3 KKK19013.1 - 1.3e-25 89.5 0.5 1.3e-25 89.5 0.4 2.4 4 0 0 4 4 4 1 Domain of unknown function (DUF3546) DUF4187 PF13821.1 KKK19013.1 - 9.4e-24 82.7 0.2 2.1e-23 81.6 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) ARS2 PF04959.8 KKK19013.1 - 1.3e-11 45.1 1.2 2.4e-11 44.2 0.2 1.9 1 1 0 1 1 1 1 Arsenite-resistance protein 2 ER_lumen_recept PF00810.13 KKK19029.1 - 1.8e-39 135.6 4.5 3.1e-39 134.8 3.1 1.4 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.9 KKK19029.1 - 0.0067 15.9 0.0 0.0067 15.9 0.0 3.5 4 0 0 4 4 4 2 PQ loop repeat HlyIII PF03006.15 KKK19029.1 - 0.13 11.7 5.8 0.17 11.2 4.0 1.2 1 0 0 1 1 1 0 Haemolysin-III related Myb_DNA-bind_3 PF12776.2 KKK19030.1 - 0.015 15.8 5.0 0.66 10.6 0.1 2.3 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 KKK19030.1 - 0.19 11.8 7.3 2 8.5 3.6 2.3 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain eRF1_1 PF03463.10 KKK19031.1 - 2.5e-47 159.7 0.0 4e-47 159.1 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_2 PF03464.10 KKK19031.1 - 2.4e-13 50.5 0.0 3.3e-09 37.1 0.0 2.3 1 1 1 2 2 2 2 eRF1 domain 2 eRF1_3 PF03465.10 KKK19031.1 - 3.5e-11 43.3 0.0 7e-11 42.3 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 3 RIO1 PF01163.17 KKK19032.1 - 0.048 13.0 0.3 0.064 12.5 0.2 1.2 1 0 0 1 1 1 0 RIO1 family DUF4551 PF15087.1 KKK19032.1 - 1 7.6 6.0 1.3 7.3 4.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) LRR_6 PF13516.1 KKK19033.1 - 5e-11 41.4 5.0 0.21 11.7 0.0 7.8 10 0 0 10 10 10 3 Leucine Rich repeat F-box-like PF12937.2 KKK19033.1 - 1.3e-10 40.7 0.0 4.8e-10 39.0 0.0 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KKK19033.1 - 1.9e-09 36.9 0.5 1e-08 34.5 0.1 2.6 3 0 0 3 3 3 1 F-box domain LRR_8 PF13855.1 KKK19033.1 - 1.2e-05 24.9 4.0 0.34 10.6 0.0 4.3 4 1 1 5 5 5 2 Leucine rich repeat LRR_4 PF12799.2 KKK19033.1 - 0.00052 19.5 4.8 0.0082 15.7 0.0 4.5 4 2 0 4 4 4 1 Leucine Rich repeats (2 copies) Sugar_tr PF00083.19 KKK19033.1 - 0.025 13.1 0.1 0.037 12.5 0.0 1.1 1 0 0 1 1 1 0 Sugar (and other) transporter LRR_1 PF00560.28 KKK19033.1 - 0.085 12.9 12.7 34 5.0 0.0 7.3 7 1 0 7 7 7 0 Leucine Rich Repeat Yippee-Mis18 PF03226.9 KKK19034.1 - 2.9e-24 84.9 2.3 3.3e-24 84.7 1.6 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly HNH_5 PF14279.1 KKK19034.1 - 0.0015 18.5 0.7 0.098 12.6 0.0 2.2 1 1 1 2 2 2 1 HNH endonuclease DUF2039 PF10217.4 KKK19034.1 - 0.012 15.5 3.2 0.016 15.2 0.3 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) Evr1_Alr PF04777.8 KKK19034.1 - 0.029 14.2 1.5 1.1 9.1 0.1 2.1 1 1 1 2 2 2 0 Erv1 / Alr family RIG-I_C-RD PF11648.3 KKK19034.1 - 0.041 13.7 1.6 0.094 12.5 1.1 1.6 1 1 0 1 1 1 0 C-terminal domain of RIG-I DZR PF12773.2 KKK19034.1 - 0.16 11.8 1.7 0.23 11.2 0.3 1.9 2 1 0 2 2 2 0 Double zinc ribbon Endonuclease_7 PF02945.10 KKK19034.1 - 0.47 10.2 4.2 0.2 11.3 0.7 2.2 1 1 1 2 2 2 0 Recombination endonuclease VII Pkinase PF00069.20 KKK19035.1 - 2e-59 200.8 0.0 2.9e-59 200.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK19035.1 - 1.3e-20 73.5 0.0 2.1e-20 72.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KKK19035.1 - 1.8e-06 27.1 0.0 3.4e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KKK19035.1 - 4.4e-05 23.3 0.1 0.0012 18.6 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 KKK19035.1 - 8e-05 21.7 0.0 0.00014 20.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KKK19035.1 - 0.001 18.4 0.0 0.0025 17.1 0.0 1.6 1 0 0 1 1 1 1 RIO1 family RabGAP-TBC PF00566.13 KKK19037.1 - 2.1e-34 118.8 3.9 2.2e-34 118.8 1.7 1.7 2 0 0 2 2 2 1 Rab-GTPase-TBC domain SPX PF03105.14 KKK19037.1 - 0.039 13.7 0.3 0.045 13.5 0.2 1.3 1 1 0 1 1 1 0 SPX domain Gp-FAR-1 PF05823.7 KKK19037.1 - 0.095 12.6 0.7 0.17 11.8 0.5 1.3 1 0 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Ribosomal_S5 PF00333.15 KKK19037.1 - 0.17 11.6 0.1 0.48 10.2 0.1 1.8 1 0 0 1 1 1 0 Ribosomal protein S5, N-terminal domain Dioxygenase_C PF00775.16 KKK19038.1 - 8e-51 171.8 0.0 1.1e-50 171.4 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.9 KKK19038.1 - 1.5e-13 50.5 0.1 2.4e-13 49.8 0.1 1.3 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.1 KKK19038.1 - 2e-05 24.5 0.0 4e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain DUF4480 PF13715.1 KKK19038.1 - 0.045 13.8 0.0 0.12 12.4 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4480) Abhydrolase_6 PF12697.2 KKK19039.1 - 3.4e-33 115.4 0.0 4e-33 115.2 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KKK19039.1 - 1.8e-20 73.2 0.4 6.7e-20 71.3 0.3 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KKK19039.1 - 2e-19 70.0 0.1 1.2e-15 57.7 0.1 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Ndr PF03096.9 KKK19039.1 - 1e-08 34.0 0.0 1.6e-08 33.3 0.0 1.3 1 1 0 1 1 1 1 Ndr family Abhydrolase_2 PF02230.11 KKK19039.1 - 2.2e-06 27.2 0.2 0.069 12.5 0.1 3.1 3 0 0 3 3 3 2 Phospholipase/Carboxylesterase BAAT_C PF08840.6 KKK19039.1 - 4.8e-06 26.4 0.1 1.2e-05 25.1 0.1 1.5 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S9 PF00326.16 KKK19039.1 - 7.9e-06 25.2 0.0 0.002 17.3 0.0 2.2 1 1 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.13 KKK19039.1 - 0.0014 17.9 0.1 1.2 8.3 0.0 2.3 2 1 0 2 2 2 2 Dienelactone hydrolase family Ser_hydrolase PF06821.8 KKK19039.1 - 0.0018 17.9 0.2 0.023 14.3 0.0 2.1 1 1 0 2 2 2 1 Serine hydrolase PGAP1 PF07819.8 KKK19039.1 - 0.0041 16.7 0.7 0.0085 15.7 0.2 1.8 2 0 0 2 2 2 1 PGAP1-like protein Esterase PF00756.15 KKK19039.1 - 0.0057 16.1 0.4 0.011 15.1 0.3 1.6 1 1 0 1 1 1 1 Putative esterase DUF676 PF05057.9 KKK19039.1 - 0.0075 15.5 0.1 0.025 13.8 0.0 1.8 1 1 1 2 2 2 1 Putative serine esterase (DUF676) Lipase_3 PF01764.20 KKK19039.1 - 0.0089 15.6 0.4 0.02 14.5 0.2 1.5 1 1 0 1 1 1 1 Lipase (class 3) UPF0227 PF05728.7 KKK19039.1 - 0.02 14.6 0.2 0.039 13.6 0.1 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0227) DUF915 PF06028.6 KKK19039.1 - 0.023 13.7 0.0 0.12 11.4 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) PAF-AH_p_II PF03403.8 KKK19039.1 - 0.039 12.2 0.2 0.95 7.6 0.0 2.3 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II Thioesterase PF00975.15 KKK19039.1 - 0.055 13.6 0.0 0.073 13.2 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain DUF2361 PF10153.4 KKK19040.1 - 3e-37 127.2 9.5 3e-37 127.2 6.6 1.8 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2361) TMF_TATA_bd PF12325.3 KKK19040.1 - 0.0032 17.1 1.9 0.47 10.2 0.7 2.6 2 0 0 2 2 2 2 TATA element modulatory factor 1 TATA binding DUF2489 PF10675.4 KKK19040.1 - 0.034 13.8 0.4 0.034 13.8 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2489) DUF4637 PF15470.1 KKK19040.1 - 0.45 10.1 6.5 6.5 6.3 1.8 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4637) PTS_2-RNA PF01885.11 KKK19041.1 - 2.2e-70 235.7 0.0 3.6e-70 235.0 0.0 1.3 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family WD40 PF00400.27 KKK19041.1 - 0.092 12.6 3.6 17 5.4 0.2 4.6 6 0 0 6 6 6 0 WD domain, G-beta repeat DUF1504 PF07399.6 KKK19041.1 - 0.24 10.0 0.0 0.36 9.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1504) Chorismate_bind PF00425.13 KKK19052.1 - 2.3e-88 295.8 0.0 3.3e-88 295.3 0.0 1.2 1 0 0 1 1 1 1 chorismate binding enzyme Anth_synt_I_N PF04715.8 KKK19052.1 - 3.2e-28 98.4 0.0 9.3e-26 90.5 0.0 3.0 3 0 0 3 3 3 2 Anthranilate synthase component I, N terminal region Cep57_MT_bd PF06657.8 KKK19053.1 - 0.11 12.3 2.2 0.23 11.4 1.5 1.5 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 Nuc_sug_transp PF04142.10 KKK19061.1 - 1.8e-21 76.3 10.9 6.9e-21 74.4 7.5 1.8 1 1 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.6 KKK19061.1 - 3.9e-07 29.3 8.9 5.8e-07 28.7 2.4 2.2 2 0 0 2 2 2 2 UAA transporter family EmrE PF13536.1 KKK19061.1 - 4.8e-06 26.7 4.0 4.8e-06 26.7 2.8 3.0 2 2 0 2 2 2 1 Multidrug resistance efflux transporter MerC PF03203.9 KKK19061.1 - 3.9 7.8 11.4 0.73 10.2 1.5 2.8 2 1 0 2 2 2 0 MerC mercury resistance protein MFS_1 PF07690.11 KKK19062.1 - 7.7e-37 126.8 54.5 9.6e-35 119.9 22.2 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2614 PF11023.3 KKK19062.1 - 2.7 7.8 6.0 0.97 9.2 0.2 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2614) PI-PLC-X PF00388.14 KKK19063.1 - 2.6e-08 33.3 0.0 3.9e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain Fungal_trans PF04082.13 KKK19064.1 - 1.8e-18 66.3 0.0 2.8e-18 65.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK19064.1 - 1.5e-08 34.4 10.1 2.9e-08 33.4 7.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PLDc_2 PF13091.1 KKK19065.1 - 1.5e-20 73.1 0.1 7.1e-10 38.7 0.0 2.2 2 0 0 2 2 2 2 PLD-like domain Regulator_TrmB PF11495.3 KKK19065.1 - 0.019 13.9 0.0 0.2 10.6 0.0 2.1 2 0 0 2 2 2 0 Archaeal transcriptional regulator TrmB PLDc PF00614.17 KKK19065.1 - 0.029 14.1 0.3 0.75 9.6 0.0 2.4 2 0 0 2 2 2 0 Phospholipase D Active site motif Transp_cyt_pur PF02133.10 KKK19066.1 - 1.8e-25 89.4 30.6 4.4e-25 88.1 21.2 1.5 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin VWA PF00092.23 KKK19067.1 - 1.8e-06 27.7 0.0 3.9e-06 26.6 0.0 1.6 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 KKK19067.1 - 0.00031 20.8 0.0 0.00095 19.3 0.0 1.8 1 1 0 1 1 1 1 von Willebrand factor type A domain His_Phos_2 PF00328.17 KKK19068.1 - 5.5e-12 45.6 0.0 9.3e-12 44.9 0.0 1.4 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) DUF3146 PF11344.3 KKK19068.1 - 0.13 11.7 0.3 4.6 6.7 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3146) zf-HC5HC2H_2 PF13832.1 KKK19073.1 - 3.4e-22 78.5 0.4 3.4e-22 78.5 0.3 4.2 4 0 0 4 4 4 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 KKK19073.1 - 3.9e-22 78.2 2.3 3.9e-22 78.2 1.6 4.8 4 0 0 4 4 4 1 PHD-like zinc-binding domain BAH PF01426.13 KKK19073.1 - 5.6e-11 42.2 0.2 1.7e-10 40.6 0.1 1.8 2 0 0 2 2 2 1 BAH domain PHD PF00628.24 KKK19073.1 - 6.2e-11 41.8 19.9 6.4e-07 28.9 3.8 5.8 7 0 0 7 7 7 3 PHD-finger PHD_2 PF13831.1 KKK19073.1 - 8.6e-10 37.7 4.5 8.6e-10 37.7 3.1 5.4 6 0 0 6 6 6 1 PHD-finger Myb_DNA-binding PF00249.26 KKK19073.1 - 4.3e-05 23.4 0.1 0.00015 21.7 0.1 2.0 1 0 0 1 1 1 1 Myb-like DNA-binding domain C1_1 PF00130.17 KKK19073.1 - 0.0039 16.8 2.0 0.0039 16.8 1.4 6.1 7 1 1 8 8 8 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.1 KKK19073.1 - 0.15 11.7 34.0 0.077 12.7 3.7 4.8 4 0 0 4 4 4 0 Prokaryotic RING finger family 1 GATase_4 PF13230.1 KKK19076.1 - 2.5e-15 55.9 0.0 7.9e-14 50.9 0.0 2.1 1 1 0 1 1 1 1 Glutamine amidotransferases class-II GATase_6 PF13522.1 KKK19076.1 - 8.6e-10 38.6 0.0 1.8e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_2 PF00310.16 KKK19076.1 - 3.1e-07 29.4 0.0 7.4e-05 21.6 0.1 2.4 2 0 0 2 2 2 2 Glutamine amidotransferases class-II DUF2956 PF11169.3 KKK19077.1 - 4.5 7.2 5.0 4 7.4 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2956) RRM_1 PF00076.17 KKK19078.1 - 1.2e-40 136.9 0.0 1.5e-21 75.7 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KKK19078.1 - 4.2e-28 97.1 0.0 3.4e-14 52.5 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KKK19078.1 - 6.3e-18 64.3 0.0 8.4e-10 38.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM PF05172.8 KKK19078.1 - 0.0073 16.0 0.0 1.5 8.6 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif M60-like PF13402.1 KKK19079.1 - 0.044 12.6 0.0 0.055 12.3 0.0 1.2 1 0 0 1 1 1 0 Peptidase M60-like family DUF2365 PF10157.4 KKK19079.1 - 0.088 12.6 0.1 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2365) DUF948 PF06103.6 KKK19079.1 - 0.089 12.6 0.9 0.28 11.0 0.6 1.9 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) FlxA PF14282.1 KKK19079.1 - 0.24 11.3 3.5 0.4 10.6 2.4 1.3 1 0 0 1 1 1 0 FlxA-like protein FlgN PF05130.7 KKK19079.1 - 0.37 11.0 5.3 0.48 10.6 3.1 1.6 1 1 1 2 2 2 0 FlgN protein Dynamin_N PF00350.18 KKK19080.1 - 9.6e-44 149.1 0.0 1.8e-43 148.2 0.0 1.5 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 KKK19080.1 - 1.2e-12 47.2 0.1 4.6e-09 35.4 0.0 2.3 2 0 0 2 2 2 2 Dynamin central region MMR_HSR1 PF01926.18 KKK19080.1 - 0.0016 18.3 0.0 0.0039 17.1 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KKK19080.1 - 0.0042 17.5 0.0 0.009 16.5 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein phiKZ_IP PF12699.2 KKK19080.1 - 0.042 12.7 0.2 0.11 11.4 0.0 1.7 2 0 0 2 2 2 0 phiKZ-like phage internal head proteins AAA_21 PF13304.1 KKK19080.1 - 0.16 11.8 0.0 0.32 10.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain Pyr_redox_2 PF07992.9 KKK19081.1 - 1.8e-26 93.2 0.0 2.3e-15 56.9 0.0 3.3 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KKK19081.1 - 2.5e-12 47.0 0.0 9.3e-11 41.9 0.0 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KKK19081.1 - 0.0019 18.2 0.0 1.3 8.9 0.0 3.0 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 KKK19081.1 - 0.7 10.1 4.4 8.7 6.6 0.0 3.7 3 1 0 3 3 3 0 Putative NAD(P)-binding 4HBT_2 PF13279.1 KKK19086.1 - 4.3e-24 85.2 0.1 8.6e-24 84.3 0.1 1.5 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.17 KKK19086.1 - 1.3e-05 25.2 0.0 2.7e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Thioesterase superfamily GCD14 PF08704.5 KKK19087.1 - 4e-06 26.5 0.3 0.013 15.0 0.0 2.6 3 0 0 3 3 3 2 tRNA methyltransferase complex GCD14 subunit HAD PF12710.2 KKK19088.1 - 9.9e-11 42.1 0.0 1.3e-10 41.8 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 KKK19088.1 - 0.0014 18.8 0.0 0.0046 17.1 0.0 1.8 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase UMPH-1 PF05822.7 KKK19088.1 - 0.0068 15.7 0.0 0.024 13.9 0.0 1.8 1 1 1 2 2 2 1 Pyrimidine 5'-nucleotidase (UMPH-1) Metallophos PF00149.23 KKK19089.1 - 1.2e-10 41.1 0.3 4.8e-10 39.1 0.2 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KKK19089.1 - 0.00012 22.0 0.4 0.00027 20.8 0.3 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain FMN_dh PF01070.13 KKK19090.1 - 3.7e-120 401.0 0.0 4.9e-120 400.6 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.20 KKK19090.1 - 7.4e-06 25.0 0.4 4.5e-05 22.5 0.1 2.0 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 KKK19090.1 - 0.00027 20.0 0.0 0.00039 19.4 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase DHO_dh PF01180.16 KKK19090.1 - 0.014 14.3 0.0 0.022 13.7 0.0 1.3 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase His_biosynth PF00977.16 KKK19090.1 - 0.056 12.7 0.0 0.35 10.0 0.0 2.2 1 1 1 2 2 2 0 Histidine biosynthesis protein Fungal_trans_2 PF11951.3 KKK19091.1 - 1.5e-58 198.2 4.9 2.2e-58 197.6 3.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK19091.1 - 6.5e-10 38.7 6.0 1.4e-09 37.6 4.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2493 PF10686.4 KKK19091.1 - 0.16 11.5 0.0 0.42 10.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2493) Aldolase_II PF00596.16 KKK19092.1 - 2.4e-48 164.1 0.2 3e-48 163.8 0.1 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Aldedh PF00171.17 KKK19093.1 - 2.7e-124 415.0 4.0 3e-124 414.8 2.7 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family HD_3 PF13023.1 KKK19095.1 - 4.1e-45 153.4 0.1 5.3e-45 153.1 0.0 1.2 1 0 0 1 1 1 1 HD domain HD PF01966.17 KKK19095.1 - 0.12 12.4 0.1 0.33 10.9 0.1 1.9 1 1 0 1 1 1 0 HD domain HAUS6_N PF14661.1 KKK19096.1 - 8.4e-48 162.8 0.1 1.3e-47 162.2 0.0 1.2 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 6 N-terminus Rad4 PF03835.10 KKK19097.1 - 9.6e-36 122.3 0.5 9.6e-36 122.3 0.4 2.0 2 0 0 2 2 2 1 Rad4 transglutaminase-like domain BHD_3 PF10405.4 KKK19097.1 - 2.1e-28 97.8 0.1 3.9e-28 96.9 0.1 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_2 PF10404.4 KKK19097.1 - 7.9e-17 61.3 0.7 7.9e-17 61.3 0.5 2.9 3 0 0 3 3 3 1 Rad4 beta-hairpin domain 2 BHD_1 PF10403.4 KKK19097.1 - 2.2e-16 59.1 0.0 4.8e-16 58.0 0.0 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 Transglut_core PF01841.14 KKK19097.1 - 0.0042 17.2 0.0 0.25 11.5 0.0 2.8 2 0 0 2 2 2 1 Transglutaminase-like superfamily DUF3420 PF11900.3 KKK19097.1 - 0.062 13.4 0.7 0.2 11.7 0.5 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3420) CoA_binding_2 PF13380.1 KKK19098.1 - 6.2e-26 90.8 0.0 7.9e-26 90.5 0.0 1.1 1 0 0 1 1 1 1 CoA binding domain LAT PF15234.1 KKK19099.1 - 3.7 6.9 8.9 1.2 8.6 3.9 1.9 2 1 0 2 2 2 0 Linker for activation of T-cells Mob1_phocein PF03637.12 KKK19100.1 - 4.8e-26 91.4 0.0 7.7e-26 90.8 0.0 1.2 1 0 0 1 1 1 1 Mob1/phocein family HIT PF01230.18 KKK19101.1 - 3.7e-23 81.8 0.1 5.3e-23 81.4 0.0 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 KKK19101.1 - 7.4e-06 26.1 0.0 1.1e-05 25.6 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding cobW PF02492.14 KKK19102.1 - 1.8e-17 63.3 0.1 2.4e-17 62.9 0.1 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain Arch_ATPase PF01637.13 KKK19102.1 - 0.00049 19.8 0.0 0.00056 19.6 0.0 1.1 1 0 0 1 1 1 1 Archaeal ATPase AAA_16 PF13191.1 KKK19102.1 - 0.0014 18.6 0.0 0.0017 18.4 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.22 KKK19102.1 - 0.004 17.4 0.0 0.0045 17.2 0.0 1.2 1 0 0 1 1 1 1 ABC transporter T2SE PF00437.15 KKK19102.1 - 0.0083 15.0 0.0 0.0088 14.9 0.0 1.1 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_29 PF13555.1 KKK19102.1 - 0.012 15.1 0.0 0.018 14.5 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.1 KKK19102.1 - 0.013 15.3 0.0 0.016 15.1 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 KKK19102.1 - 0.013 15.5 0.0 0.016 15.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 KKK19102.1 - 0.015 15.0 0.1 0.023 14.4 0.1 1.4 1 0 0 1 1 1 0 Part of AAA domain MMR_HSR1 PF01926.18 KKK19102.1 - 0.015 15.2 0.1 0.02 14.8 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_14 PF13173.1 KKK19102.1 - 0.015 15.1 0.0 0.019 14.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 KKK19102.1 - 0.018 14.1 0.0 0.021 13.9 0.0 1.1 1 0 0 1 1 1 0 Zeta toxin MobB PF03205.9 KKK19102.1 - 0.019 14.6 0.1 0.024 14.3 0.1 1.2 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_23 PF13476.1 KKK19102.1 - 0.02 15.2 0.3 0.029 14.6 0.2 1.3 1 1 0 1 1 1 0 AAA domain Miro PF08477.8 KKK19102.1 - 0.02 15.3 0.0 0.029 14.8 0.0 1.2 1 0 0 1 1 1 0 Miro-like protein AAA_18 PF13238.1 KKK19102.1 - 0.029 14.6 0.1 0.04 14.2 0.1 1.2 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 KKK19102.1 - 0.035 13.5 0.0 0.049 13.0 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain DUF258 PF03193.11 KKK19102.1 - 0.039 13.1 0.0 0.042 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF258 SRP54 PF00448.17 KKK19102.1 - 0.06 12.7 0.0 0.072 12.5 0.0 1.1 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain SoxE PF06525.6 KKK19102.1 - 0.066 12.4 0.0 0.08 12.2 0.0 1.1 1 0 0 1 1 1 0 Sulfocyanin (SoxE) Viral_helicase1 PF01443.13 KKK19102.1 - 0.082 12.4 0.0 0.097 12.1 0.0 1.1 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase ArgK PF03308.11 KKK19102.1 - 0.087 11.5 0.0 0.1 11.3 0.0 1.1 1 0 0 1 1 1 0 ArgK protein UPF0079 PF02367.12 KKK19102.1 - 0.091 12.3 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Rad17 PF03215.10 KKK19102.1 - 0.093 11.3 0.0 0.11 11.1 0.0 1.0 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein DUF2791 PF10923.3 KKK19102.1 - 0.13 10.8 0.0 0.16 10.5 0.0 1.0 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) Inp1 PF12634.2 KKK19131.1 - 8e-35 119.6 0.0 1.9e-34 118.4 0.0 1.6 1 0 0 1 1 1 1 Inheritance of peroxisomes protein 1 EI24 PF07264.6 KKK19132.1 - 3.1e-06 26.7 2.8 3.1e-06 26.7 2.0 3.5 2 2 1 3 3 3 1 Etoposide-induced protein 2.4 (EI24) FmdA_AmdA PF03069.10 KKK19133.1 - 8.1e-156 518.3 0.0 9.2e-156 518.1 0.0 1.0 1 0 0 1 1 1 1 Acetamidase/Formamidase family FAD_binding_3 PF01494.14 KKK19134.1 - 1.4e-08 34.2 1.0 1.3e-07 31.0 0.7 2.0 1 1 0 1 1 1 1 FAD binding domain SRP14 PF02290.10 KKK19135.1 - 6.4e-26 90.1 0.2 8.4e-26 89.7 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle 14kD protein Alb1 PF09135.6 KKK19135.1 - 0.96 10.0 7.9 1.3 9.7 5.5 1.2 1 0 0 1 1 1 0 Alb1 WAC_Acf1_DNA_bd PF10537.4 KKK19140.1 - 1.1e-41 141.1 1.0 6.2e-41 138.7 0.7 2.4 1 0 0 1 1 1 1 ATP-utilising chromatin assembly and remodelling N-terminal DDT PF02791.12 KKK19140.1 - 5.5e-19 67.6 2.0 1.1e-18 66.7 1.4 1.5 1 0 0 1 1 1 1 DDT domain WHIM2 PF15613.1 KKK19140.1 - 3.7e-09 36.1 0.3 7.7e-09 35.1 0.2 1.6 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 2 WHIM3 PF15614.1 KKK19140.1 - 0.00024 20.8 1.1 0.00065 19.4 0.8 1.7 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 3 WHIM1 PF15612.1 KKK19140.1 - 0.00044 20.0 0.1 0.00044 20.0 0.1 2.4 2 0 0 2 2 2 1 WSTF, HB1, Itc1p, MBD9 motif 1 PLDc_2 PF13091.1 KKK19141.1 - 2.3e-13 49.9 0.0 1.1e-05 25.2 0.0 3.2 3 1 0 3 3 3 2 PLD-like domain PLDc PF00614.17 KKK19141.1 - 1.6e-11 43.6 2.5 4.7e-05 23.0 0.2 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif Regulator_TrmB PF11495.3 KKK19141.1 - 0.27 10.1 0.1 1.2 8.1 0.0 2.0 2 0 0 2 2 2 0 Archaeal transcriptional regulator TrmB DEAD PF00270.24 KKK19142.1 - 2.2e-18 66.3 0.0 5.6e-18 64.9 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 KKK19142.1 - 1.3e-07 31.6 0.0 9.1e-07 28.8 0.0 2.5 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 KKK19142.1 - 3.9e-06 26.6 0.2 9.4e-06 25.4 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PhoH PF02562.11 KKK19142.1 - 0.1 11.7 0.0 0.23 10.6 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein zf-DHHC PF01529.15 KKK19143.1 - 4.4e-40 136.8 0.2 4.4e-40 136.8 0.2 2.9 3 1 0 3 3 3 1 DHHC palmitoyltransferase Rhomboid PF01694.17 KKK19143.1 - 2.6e-33 115.1 10.8 2.6e-33 115.1 7.5 2.9 4 0 0 4 4 4 1 Rhomboid family DZR PF12773.2 KKK19143.1 - 0.051 13.3 6.6 0.11 12.2 4.6 1.6 1 0 0 1 1 1 0 Double zinc ribbon Vma12 PF11712.3 KKK19143.1 - 5.1 6.7 8.5 8.7 6.0 0.1 3.9 4 0 0 4 4 4 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Kinetochor_Ybp2 PF08568.5 KKK19144.1 - 6.9e-146 487.0 0.1 9.8e-145 483.2 0.1 1.9 1 1 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin UQ_con PF00179.21 KKK19146.1 - 2.1e-22 79.0 0.0 3e-22 78.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme VCBS PF13517.1 KKK19146.1 - 0.45 10.9 2.5 3.1 8.2 1.8 2.2 1 1 0 1 1 1 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella p450 PF00067.17 KKK19147.1 - 1.3e-63 215.2 0.0 2.5e-63 214.2 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 Snf7 PF03357.16 KKK19148.1 - 6e-18 64.8 20.5 8e-18 64.4 13.8 1.5 1 1 0 1 1 1 1 Snf7 PspA_IM30 PF04012.7 KKK19148.1 - 0.1 11.9 28.3 0.25 10.6 17.4 2.6 1 1 0 1 1 1 0 PspA/IM30 family MutS_III PF05192.13 KKK19148.1 - 0.17 11.6 10.6 4.3 7.0 4.4 2.4 1 1 1 2 2 2 0 MutS domain III DUF4610 PF15384.1 KKK19148.1 - 0.28 10.6 3.4 0.26 10.7 0.5 2.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4610) DUF885 PF05960.6 KKK19148.1 - 0.59 9.2 13.7 0.74 8.9 1.7 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF885) DUF2203 PF09969.4 KKK19148.1 - 1.9 8.7 14.2 0.14 12.4 1.9 2.9 1 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Syntaxin PF00804.20 KKK19148.1 - 6.7 6.9 21.5 0.09 12.9 5.3 3.1 1 1 1 2 2 2 0 Syntaxin TRAPPC-Trs85 PF12739.2 KKK19149.1 - 2.8e-117 391.8 0.0 4.2e-117 391.2 0.0 1.2 1 0 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit CDC27 PF09507.5 KKK19150.1 - 8.4e-120 400.8 20.7 9.5e-120 400.7 14.3 1.0 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 zf-C3HC4_2 PF13923.1 KKK19151.1 - 1.1e-08 34.8 20.9 2.4e-08 33.8 9.5 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KKK19151.1 - 1.3e-07 31.3 18.8 2.8e-07 30.2 9.1 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 KKK19151.1 - 1.6e-07 30.8 13.0 1.6e-07 30.8 9.0 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KKK19151.1 - 3e-07 30.0 16.7 8.4e-07 28.6 9.3 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KKK19151.1 - 6.2e-07 28.9 17.1 6.5e-07 28.9 7.5 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) SAP PF02037.22 KKK19151.1 - 1.3e-06 27.7 0.0 2.8e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 SAP domain zf-RING_6 PF14835.1 KKK19151.1 - 5.8e-06 25.9 5.9 5.8e-06 25.9 4.1 2.1 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.1 KKK19151.1 - 3.7e-05 23.4 12.9 3.7e-05 23.4 9.0 2.3 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 KKK19151.1 - 0.00012 21.7 11.7 0.00062 19.4 5.9 2.8 2 0 0 2 2 2 1 RING-type zinc-finger Mob_synth_C PF06463.8 KKK19151.1 - 0.00031 20.4 2.2 0.00069 19.3 1.5 1.5 1 0 0 1 1 1 1 Molybdenum Cofactor Synthesis C zf-rbx1 PF12678.2 KKK19151.1 - 0.0018 18.3 8.7 0.0024 17.9 4.2 2.2 2 0 0 2 2 2 1 RING-H2 zinc finger U-box PF04564.10 KKK19151.1 - 0.057 13.3 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 U-box domain zf-RING_4 PF14570.1 KKK19151.1 - 0.1 12.1 14.1 0.089 12.3 6.9 2.6 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain Rad50_zn_hook PF04423.9 KKK19151.1 - 0.3 10.5 0.1 0.3 10.5 0.0 3.3 3 0 0 3 3 3 0 Rad50 zinc hook motif zf-Apc11 PF12861.2 KKK19151.1 - 0.54 10.1 7.0 0.11 12.3 2.1 1.9 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-met PF12874.2 KKK19151.1 - 1.2 9.4 0.1 1.2 9.4 0.0 2.9 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Pex2_Pex12 PF04757.9 KKK19152.1 - 1.9e-58 197.5 2.3 2.4e-58 197.2 1.6 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_4 PF15227.1 KKK19152.1 - 7.2e-06 25.7 3.4 1.3e-05 24.9 2.3 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 KKK19152.1 - 2.1e-05 24.4 3.1 2.1e-05 24.4 2.1 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KKK19152.1 - 0.004 16.9 2.2 0.004 16.9 1.6 1.6 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 KKK19152.1 - 0.02 14.5 2.4 0.035 13.7 1.6 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KKK19152.1 - 0.11 12.1 1.5 0.2 11.3 1.1 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF1237 PF06824.6 KKK19153.1 - 3.3e-185 615.7 0.0 3.8e-185 615.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1237) Mito_carr PF00153.22 KKK19154.1 - 6.7e-62 205.2 3.6 5.7e-21 74.0 0.0 4.3 3 1 0 3 3 3 3 Mitochondrial carrier protein Oligomerisation PF02410.10 KKK19155.1 - 0.00019 21.4 0.0 0.0028 17.6 0.0 2.4 1 1 0 1 1 1 1 Oligomerisation domain PolyA_pol PF01743.15 KKK19156.1 - 4.7e-23 81.7 0.2 1.1e-22 80.6 0.1 1.6 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.2 KKK19156.1 - 6.3e-07 28.8 0.0 1.6e-06 27.5 0.0 1.7 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A tRNA_NucTran2_2 PF13735.1 KKK19156.1 - 0.0011 18.8 0.1 0.0031 17.3 0.0 1.8 2 0 0 2 2 2 1 tRNA nucleotidyltransferase domain 2 putative DUF2454 PF10521.4 KKK19157.1 - 5.6e-96 320.8 0.5 7.9e-96 320.3 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2454) DUF1395 PF07160.7 KKK19158.1 - 0.022 14.2 0.8 0.034 13.6 0.1 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1395) Abhydrolase_4 PF08386.5 KKK19159.1 - 2.1e-18 66.0 0.0 6e-18 64.6 0.0 1.7 2 0 0 2 2 2 1 TAP-like protein Abhydrolase_6 PF12697.2 KKK19159.1 - 7.6e-10 39.0 0.3 7e-09 35.9 0.0 2.7 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KKK19159.1 - 1.7e-07 31.0 0.0 8.7e-06 25.4 0.0 2.9 3 0 0 3 3 3 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KKK19159.1 - 0.00076 19.2 0.0 1.2 8.8 0.0 2.6 2 1 0 2 2 2 2 Alpha/beta hydrolase family DUF2920 PF11144.3 KKK19159.1 - 0.13 11.2 0.0 0.21 10.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) DAO PF01266.19 KKK19160.1 - 8.5e-53 179.5 0.0 9.8e-53 179.3 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KKK19160.1 - 9.9e-05 22.3 0.4 0.0079 16.0 0.3 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 KKK19160.1 - 0.00015 21.7 0.1 0.0081 16.1 0.0 2.4 2 0 0 2 2 2 1 TrkA-N domain NAD_binding_8 PF13450.1 KKK19160.1 - 0.0021 18.0 0.1 0.0042 17.0 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 KKK19160.1 - 0.0048 15.8 0.2 0.12 11.1 0.0 2.3 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox PF00070.22 KKK19160.1 - 0.0057 17.0 0.1 0.015 15.6 0.1 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KKK19160.1 - 0.11 11.5 0.2 0.21 10.6 0.1 1.5 1 0 0 1 1 1 0 Thi4 family DNA_pol_B PF00136.16 KKK19161.1 - 5.1e-146 487.1 3.9 7e-146 486.6 2.7 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 KKK19161.1 - 1.2e-83 280.6 0.1 2.9e-83 279.4 0.1 1.7 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 KKK19161.1 - 1.6e-24 85.6 4.9 3.6e-24 84.5 3.4 1.6 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta RNase_H_2 PF13482.1 KKK19161.1 - 5.6e-05 23.0 0.3 0.00027 20.7 0.2 2.3 1 1 0 1 1 1 1 RNase_H superfamily Podoplanin PF05808.6 KKK19162.1 - 0.0016 18.0 0.1 0.0024 17.4 0.0 1.3 1 0 0 1 1 1 1 Podoplanin SOG2 PF10428.4 KKK19163.1 - 1.2 7.7 11.5 1.4 7.4 8.0 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Macoilin PF09726.4 KKK19163.1 - 2 6.5 7.4 2.3 6.3 5.1 1.0 1 0 0 1 1 1 0 Transmembrane protein PAP1 PF08601.5 KKK19163.1 - 9.7 5.7 13.0 12 5.4 9.0 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 Syja_N PF02383.13 KKK19164.1 - 5.2e-93 311.3 0.1 1e-92 310.3 0.0 1.4 1 0 0 1 1 1 1 SacI homology domain Pkinase PF00069.20 KKK19165.1 - 7.8e-34 116.9 0.0 2.1e-20 72.9 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KKK19165.1 - 1.3e-18 66.9 0.0 1e-06 28.0 0.0 3.2 3 0 0 3 3 3 3 Protein tyrosine kinase Kinase-like PF14531.1 KKK19165.1 - 0.035 13.0 0.0 0.22 10.4 0.0 2.2 3 0 0 3 3 3 0 Kinase-like FXa_inhibition PF14670.1 KKK19165.1 - 0.082 13.0 0.5 0.17 12.0 0.3 1.5 1 0 0 1 1 1 0 Coagulation Factor Xa inhibitory site Hamartin PF04388.7 KKK19166.1 - 0.16 10.5 0.1 0.18 10.4 0.0 1.0 1 0 0 1 1 1 0 Hamartin protein Cyanate_lyase PF02560.9 KKK19167.1 - 2.2e-23 81.5 0.0 5.3e-23 80.3 0.0 1.6 1 0 0 1 1 1 1 Cyanate lyase C-terminal domain zf-C2H2_4 PF13894.1 KKK19167.1 - 3.1e-09 36.4 14.3 0.33 11.3 0.0 6.4 6 0 0 6 6 6 3 C2H2-type zinc finger zf-C2H2 PF00096.21 KKK19167.1 - 9.8e-09 35.0 17.7 0.15 12.4 0.1 6.0 6 0 0 6 6 6 3 Zinc finger, C2H2 type zf-Di19 PF05605.7 KKK19167.1 - 6.8e-06 26.1 8.7 0.045 13.8 1.5 3.7 2 1 0 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.1 KKK19167.1 - 2.9e-05 24.1 12.4 0.35 11.2 0.2 4.6 4 0 0 4 4 4 2 Zinc-finger double domain Rad50_zn_hook PF04423.9 KKK19167.1 - 0.00012 21.4 14.4 0.00018 20.9 0.1 4.9 3 1 2 5 5 5 1 Rad50 zinc hook motif zf-C2H2_jaz PF12171.3 KKK19167.1 - 0.0011 19.0 8.6 4.3 7.5 0.4 5.9 5 1 1 6 6 6 1 Zinc-finger double-stranded RNA-binding zf-RING_4 PF14570.1 KKK19167.1 - 0.0021 17.6 10.5 5.2 6.7 0.1 4.5 4 0 0 4 4 4 1 RING/Ubox like zinc-binding domain zinc_ribbon_5 PF13719.1 KKK19167.1 - 0.0042 16.6 11.0 3.5 7.2 0.1 4.0 3 1 0 3 3 3 2 zinc-ribbon domain zinc_ribbon_4 PF13717.1 KKK19167.1 - 0.0046 16.6 10.9 4.6 7.0 0.1 3.9 3 1 0 3 3 3 1 zinc-ribbon domain DUF2225 PF09986.4 KKK19167.1 - 0.015 14.7 8.7 0.1 12.0 0.0 3.9 3 1 1 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2225) zf-C2H2_6 PF13912.1 KKK19167.1 - 0.018 14.9 16.1 4.7 7.2 0.0 5.9 6 0 0 6 6 6 0 C2H2-type zinc finger GAGA PF09237.6 KKK19167.1 - 0.058 12.9 3.5 0.067 12.7 0.0 2.6 3 0 0 3 3 3 0 GAGA factor Zn-ribbon_8 PF09723.5 KKK19167.1 - 0.083 12.8 13.3 0.61 10.0 1.7 4.4 3 1 1 4 4 4 0 Zinc ribbon domain PhnA_Zn_Ribbon PF08274.7 KKK19167.1 - 0.11 12.2 0.1 0.11 12.2 0.1 3.1 3 1 0 3 3 2 0 PhnA Zinc-Ribbon zf-met PF12874.2 KKK19167.1 - 0.15 12.3 8.8 14 6.0 0.0 5.0 6 0 0 6 6 5 0 Zinc-finger of C2H2 type Peptidase_G2 PF11962.3 KKK19167.1 - 0.17 11.0 1.4 6.7 5.7 0.1 2.2 2 0 0 2 2 2 0 Peptidase_G2, IMC autoproteolytic cleavage domain zf-C2HC_2 PF13913.1 KKK19167.1 - 0.3 10.8 8.4 3.3 7.4 0.1 4.2 4 0 0 4 4 4 0 zinc-finger of a C2HC-type zf-C2H2_2 PF12756.2 KKK19167.1 - 0.36 10.9 13.6 3.9 7.6 2.1 3.6 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-CSL PF05207.8 KKK19167.1 - 0.51 9.8 8.1 0.85 9.1 0.2 3.0 3 0 0 3 3 3 0 CSL zinc finger zf-RING_3 PF14369.1 KKK19167.1 - 0.6 10.1 9.2 18 5.4 0.2 4.3 4 0 0 4 4 4 0 zinc-finger CpXC PF14353.1 KKK19167.1 - 1 9.3 11.7 10 6.1 0.1 4.0 2 1 3 5 5 5 0 CpXC protein DZR PF12773.2 KKK19167.1 - 1.7 8.5 15.8 4.4 7.2 5.7 3.4 2 1 0 2 2 2 0 Double zinc ribbon zinc-ribbons_6 PF07191.7 KKK19167.1 - 3.8 7.3 13.1 1.3 8.8 0.2 3.7 3 1 2 5 5 4 0 zinc-ribbons UPF0547 PF10571.4 KKK19167.1 - 4.7 7.0 13.9 0.82 9.4 0.9 4.4 4 0 0 4 4 4 0 Uncharacterised protein family UPF0547 IBR PF01485.16 KKK19167.1 - 5.6 6.9 15.4 0.19 11.5 1.1 3.8 2 2 1 3 3 3 0 IBR domain zf-RING_5 PF14634.1 KKK19167.1 - 8.6 6.1 11.1 2.8 7.7 3.8 2.8 2 1 0 2 2 2 0 zinc-RING finger domain MBF1 PF08523.5 KKK19178.1 - 8.9e-26 89.7 1.9 1.5e-25 88.9 0.4 1.9 2 0 0 2 2 2 1 Multiprotein bridging factor 1 HTH_3 PF01381.17 KKK19178.1 - 2.5e-11 43.2 0.0 3.6e-11 42.7 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.1 KKK19178.1 - 2.1e-05 24.5 0.0 4e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.2 KKK19178.1 - 0.00024 21.0 0.0 0.00036 20.5 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain WD40 PF00400.27 KKK19179.1 - 1.3e-31 107.3 2.7 9.6e-11 41.1 0.0 6.4 6 1 0 6 6 6 4 WD domain, G-beta repeat Nup160 PF11715.3 KKK19179.1 - 0.00075 17.7 0.4 0.0012 17.0 0.2 1.4 1 1 0 1 1 1 1 Nucleoporin Nup120/160 PQQ_2 PF13360.1 KKK19179.1 - 0.0026 17.2 1.1 0.024 14.1 0.8 2.2 1 1 0 1 1 1 1 PQQ-like domain Gmad1 PF10647.4 KKK19179.1 - 0.0065 15.8 0.0 0.011 15.2 0.0 1.4 1 0 0 1 1 1 1 Lipoprotein LpqB beta-propeller domain Pyr_redox_2 PF07992.9 KKK19179.1 - 0.011 15.5 0.0 4.5 7.0 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Ank_2 PF12796.2 KKK19180.1 - 2.6e-61 203.9 23.3 3.4e-21 75.3 1.1 4.3 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 KKK19180.1 - 8.1e-32 107.4 7.4 1.6e-07 30.7 0.0 7.6 6 1 1 7 7 7 4 Ankyrin repeat Ank_4 PF13637.1 KKK19180.1 - 3.3e-26 91.1 2.3 3.4e-12 46.5 0.0 5.3 2 1 4 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 KKK19180.1 - 1.3e-19 68.2 8.8 0.00083 19.3 0.0 8.1 9 0 0 9 9 9 4 Ankyrin repeat Ank_5 PF13857.1 KKK19180.1 - 1.2e-17 63.5 8.5 3.4e-08 33.4 0.2 5.3 4 1 3 7 7 7 4 Ankyrin repeats (many copies) SH3_1 PF00018.23 KKK19181.1 - 2.1e-14 52.6 0.0 3.1e-14 52.0 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KKK19181.1 - 7.5e-12 44.6 0.1 1.6e-11 43.5 0.0 1.6 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 KKK19181.1 - 9.1e-08 31.4 0.0 1.5e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain Iso_dh PF00180.15 KKK19182.1 - 4.9e-71 239.4 0.0 6e-71 239.1 0.0 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Methyltransf_23 PF13489.1 KKK19183.1 - 1.1e-06 28.4 0.2 1.9e-06 27.7 0.2 1.3 1 0 0 1 1 1 1 Methyltransferase domain FTHFS PF01268.14 KKK19184.1 - 8.6e-255 845.9 0.0 1.2e-254 845.5 0.0 1.2 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.14 KKK19184.1 - 3.2e-67 224.6 1.1 7.6e-67 223.3 0.8 1.7 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 KKK19184.1 - 2.7e-38 130.6 0.9 8e-38 129.0 0.6 1.9 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain eIF-5_eIF-2B PF01873.12 KKK19185.1 - 2e-44 150.2 0.1 3.1e-44 149.6 0.1 1.2 1 0 0 1 1 1 1 Domain found in IF2B/IF5 Lar_restr_allev PF14354.1 KKK19185.1 - 0.12 12.7 0.7 0.38 11.1 0.5 1.9 1 1 0 1 1 1 0 Restriction alleviation protein Lar Arc_trans_TRASH PF08394.5 KKK19185.1 - 1.4 9.0 7.1 1.1 9.4 0.2 2.7 1 1 1 2 2 2 0 Archaeal TRASH domain AIM24 PF01987.12 KKK19186.1 - 1.3e-52 178.3 0.1 1.6e-52 178.1 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 ChaC PF04752.7 KKK19189.1 - 2.4e-54 183.9 0.0 3.2e-54 183.5 0.0 1.1 1 0 0 1 1 1 1 ChaC-like protein RRM_1 PF00076.17 KKK19190.1 - 7.6e-22 76.7 0.0 1e-21 76.2 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KKK19190.1 - 3.1e-15 55.9 0.0 4.2e-15 55.4 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KKK19190.1 - 2.9e-11 43.0 0.0 3.7e-11 42.6 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KKK19190.1 - 0.015 15.1 0.1 0.024 14.4 0.1 1.3 1 0 0 1 1 1 0 RNA binding motif EF-hand_1 PF00036.27 KKK19191.1 - 1.2e-21 74.2 4.4 6e-07 28.3 0.0 4.7 4 1 0 4 4 4 3 EF hand EF-hand_6 PF13405.1 KKK19191.1 - 3.2e-20 70.1 1.8 4.8e-06 26.0 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.1 KKK19191.1 - 8e-20 70.7 0.8 3e-09 36.8 0.5 2.9 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 KKK19191.1 - 5.5e-17 61.1 1.3 2.8e-08 33.2 0.0 3.6 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.1 KKK19191.1 - 2.6e-14 51.7 7.8 2.7e-05 23.2 0.2 4.1 4 1 0 4 4 4 3 EF hand EF-hand_10 PF14788.1 KKK19191.1 - 0.083 12.5 0.2 24 4.6 0.0 2.8 3 0 0 3 3 3 0 EF hand adh_short PF00106.20 KKK19192.1 - 5.9e-14 52.3 0.0 8.9e-14 51.7 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KKK19192.1 - 7.6e-07 28.9 0.0 1.1e-06 28.4 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KKK19192.1 - 1e-05 25.4 0.0 0.0037 17.0 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase MFS_1 PF07690.11 KKK19193.1 - 1.7e-49 168.4 55.3 1.7e-49 168.4 38.3 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KKK19193.1 - 1.1e-16 60.1 19.9 4.4e-16 58.2 13.8 1.8 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 KKK19193.1 - 2.4e-13 49.4 13.9 2.4e-13 49.4 9.7 3.8 1 1 2 4 4 4 2 Sugar (and other) transporter RskA PF10099.4 KKK19193.1 - 1.1 8.9 4.2 2.7 7.7 0.2 2.6 2 1 0 2 2 2 0 Anti-sigma-K factor rskA SKG6 PF08693.5 KKK19196.1 - 3.2e-06 26.3 1.9 9.1e-06 24.8 1.3 1.8 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF4448 PF14610.1 KKK19196.1 - 6e-06 25.8 0.0 9.5e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) DUF3188 PF11384.3 KKK19196.1 - 0.0025 17.3 0.7 0.0044 16.5 0.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3188) TMEM154 PF15102.1 KKK19196.1 - 0.0034 17.1 0.4 0.0064 16.1 0.3 1.4 1 0 0 1 1 1 1 TMEM154 protein family RCR PF12273.3 KKK19196.1 - 0.023 15.2 7.0 0.023 15.2 4.9 2.4 2 1 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red Adeno_E3_CR2 PF02439.10 KKK19196.1 - 0.033 13.7 0.1 0.058 12.9 0.1 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Mem_trans PF03547.13 KKK19196.1 - 0.18 10.0 4.3 1.4 7.1 0.0 2.1 1 1 0 2 2 2 0 Membrane transport protein DUF912 PF06024.7 KKK19196.1 - 0.19 11.8 5.6 2.9 8.0 3.9 2.2 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) ELO PF01151.13 KKK19199.1 - 1.6e-86 289.6 5.8 2e-86 289.3 4.1 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family Glyco_hydro_35 PF01301.14 KKK19200.1 - 6.9e-72 242.4 3.2 6.9e-72 242.4 2.2 2.2 2 1 0 2 2 2 1 Glycosyl hydrolases family 35 BetaGal_dom2 PF10435.4 KKK19200.1 - 2.7e-69 232.2 0.4 5e-69 231.3 0.3 1.5 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom4_5 PF13364.1 KKK19200.1 - 9.4e-52 173.9 12.5 6.6e-28 97.2 1.2 3.1 3 0 0 3 3 3 2 Beta-galactosidase jelly roll domain BetaGal_dom3 PF13363.1 KKK19200.1 - 3e-27 93.8 0.0 6.6e-27 92.7 0.0 1.6 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 MFS_1 PF07690.11 KKK19201.1 - 6.1e-36 123.8 23.0 9e-36 123.3 15.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily TAF4 PF05236.9 KKK19203.1 - 4.4e-19 68.7 0.5 3.1e-06 26.6 0.3 3.2 3 0 0 3 3 3 3 Transcription initiation factor TFIID component TAF4 family Pkinase PF00069.20 KKK19204.1 - 3.5e-54 183.6 0.1 1e-53 182.1 0.1 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK19204.1 - 4.4e-20 71.8 0.0 5.9e-19 68.1 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase TruD PF01142.13 KKK19205.1 - 1.2e-50 172.3 0.0 3.6e-46 157.5 0.0 4.3 2 1 0 2 2 2 2 tRNA pseudouridine synthase D (TruD) CPSF73-100_C PF11718.3 KKK19206.1 - 1.2e-76 256.8 0.2 3.6e-75 252.0 0.1 2.2 1 1 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.3 KKK19206.1 - 8.9e-32 109.6 0.0 1.9e-31 108.6 0.0 1.6 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B PF00753.22 KKK19206.1 - 1.5e-17 63.8 0.1 3.1e-17 62.8 0.1 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KKK19206.1 - 5.3e-11 42.4 0.3 1e-10 41.4 0.2 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain RMMBL PF07521.7 KKK19206.1 - 6.4e-07 29.0 0.1 1.2e-06 28.1 0.1 1.5 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B_3 PF13483.1 KKK19206.1 - 9.8e-05 22.1 0.2 0.00037 20.2 0.1 2.0 1 1 0 1 1 1 1 Beta-lactamase superfamily domain DDE_3 PF13358.1 KKK19219.1 - 0.0024 17.6 0.0 0.0025 17.5 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease TMA7 PF09072.5 KKK19237.1 - 8.3e-27 93.4 17.0 9.2e-27 93.2 11.8 1.0 1 0 0 1 1 1 1 Translation machinery associated TMA7 Pkinase PF00069.20 KKK19239.1 - 1.8e-59 201.0 0.0 2.3e-59 200.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK19239.1 - 1e-32 113.2 0.0 1.2e-32 113.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KKK19239.1 - 0.0014 17.6 0.0 0.0024 16.8 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.9 KKK19239.1 - 0.0081 15.2 0.0 0.012 14.6 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KKK19239.1 - 0.012 15.3 0.0 0.024 14.3 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 KKK19239.1 - 0.13 11.0 0.0 0.2 10.4 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Choline_kinase PF01633.15 KKK19239.1 - 0.15 11.5 0.0 0.27 10.7 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pkinase PF00069.20 KKK19240.1 - 2.1e-54 184.4 0.0 3.3e-54 183.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK19240.1 - 2.2e-23 82.6 0.0 8.7e-23 80.7 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 KKK19240.1 - 0.02 13.7 0.1 0.03 13.1 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Cyt-b5 PF00173.23 KKK19241.1 - 0.085 12.6 0.0 0.1 12.3 0.0 1.1 1 0 0 1 1 1 0 Cytochrome b5-like Heme/Steroid binding domain HlyIII PF03006.15 KKK19242.1 - 1e-62 211.4 11.5 1.2e-62 211.2 8.0 1.1 1 0 0 1 1 1 1 Haemolysin-III related TFIIB PF00382.14 KKK19244.1 - 5.6e-39 131.8 0.1 4e-19 68.1 0.1 2.5 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 KKK19244.1 - 8.1e-10 37.8 1.0 8.1e-10 37.8 0.7 1.7 2 0 0 2 2 2 1 TFIIB zinc-binding Sigma70_r4 PF04545.11 KKK19244.1 - 0.078 12.3 0.0 0.37 10.1 0.0 2.1 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_23 PF13384.1 KKK19244.1 - 0.12 12.0 0.0 0.35 10.5 0.0 1.8 1 0 0 1 1 1 0 Homeodomain-like domain ATP_sub_h PF10775.4 KKK19245.1 - 6.7e-27 93.0 0.3 9.4e-27 92.5 0.2 1.2 1 0 0 1 1 1 1 ATP synthase complex subunit h ATP-synt_F6 PF05511.6 KKK19245.1 - 5.3e-05 23.0 0.1 7.3e-05 22.5 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial ATP synthase coupling factor 6 SAC3_GANP PF03399.11 KKK19246.1 - 2.5e-07 30.4 0.0 4.5e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 KKK19246.1 - 0.011 15.4 0.1 0.021 14.5 0.1 1.4 1 0 0 1 1 1 0 COP9 signalosome, subunit CSN8 DUF3024 PF11225.3 KKK19246.1 - 0.068 13.0 0.1 0.19 11.6 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3024) TPR_19 PF14559.1 KKK19247.1 - 1e-13 51.4 0.3 6.2e-05 23.2 0.0 3.3 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 KKK19247.1 - 6e-09 36.3 0.0 0.0063 17.1 0.1 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat BTAD PF03704.12 KKK19247.1 - 6.9e-05 23.1 4.2 0.054 13.8 0.3 2.3 2 0 0 2 2 2 2 Bacterial transcriptional activator domain TPR_2 PF07719.12 KKK19247.1 - 0.00015 21.4 0.1 0.27 11.2 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_21 PF09976.4 KKK19247.1 - 0.0018 18.1 0.4 0.16 11.8 0.0 2.4 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 KKK19247.1 - 0.0019 18.5 0.4 7.4 7.2 0.0 3.7 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 KKK19247.1 - 0.002 17.7 0.0 0.25 11.0 0.0 2.9 2 1 1 3 3 3 2 TPR repeat TPR_14 PF13428.1 KKK19247.1 - 0.021 15.4 0.3 13 6.7 0.0 3.6 3 1 1 4 4 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 KKK19247.1 - 0.055 13.4 1.3 0.39 10.6 0.1 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Coatomer_E PF04733.9 KKK19247.1 - 0.11 11.6 0.5 0.6 9.2 0.1 1.9 2 0 0 2 2 2 0 Coatomer epsilon subunit NARP1 PF12569.3 KKK19247.1 - 0.18 10.5 0.0 0.32 9.6 0.0 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 SLT_L PF14718.1 KKK19247.1 - 0.38 10.5 2.9 4 7.3 0.2 2.8 2 1 0 2 2 2 0 Soluble lytic murein transglycosylase L domain TPR_10 PF13374.1 KKK19247.1 - 0.49 10.3 2.7 0.99 9.4 0.2 2.7 3 0 0 3 3 2 0 Tetratricopeptide repeat Cg6151-P PF10233.4 KKK19248.1 - 4.6e-43 145.7 15.1 5.6e-43 145.5 10.5 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P COPI_assoc PF08507.5 KKK19248.1 - 0.0021 17.7 13.7 0.003 17.2 9.5 1.2 1 0 0 1 1 1 1 COPI associated protein DUF599 PF04654.7 KKK19248.1 - 0.017 14.2 2.3 0.02 14.0 1.4 1.4 1 1 0 1 1 1 0 Protein of unknown function, DUF599 DUF2207 PF09972.4 KKK19248.1 - 0.04 12.4 5.3 0.051 12.1 3.7 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Viral_Beta_CD PF04530.7 KKK19248.1 - 0.43 10.7 2.8 4.2 7.5 0.0 2.2 2 0 0 2 2 2 0 Viral Beta C/D like family YtpI PF14007.1 KKK19248.1 - 8.4 6.3 15.2 7.1 6.6 4.9 2.7 1 1 2 3 3 3 0 YtpI-like protein DUF3210 PF11489.3 KKK19249.1 - 1.2e-266 887.0 67.7 1.2e-266 887.0 46.9 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3210) SRF-TF PF00319.13 KKK19274.1 - 1.4e-23 81.8 0.2 2e-23 81.3 0.2 1.2 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) CDC45 PF02724.9 KKK19274.1 - 0.014 13.5 0.2 0.019 13.0 0.2 1.2 1 0 0 1 1 1 0 CDC45-like protein Mg_trans_NIPA PF05653.9 KKK19275.1 - 1.4e-16 60.3 11.1 5.3e-09 35.4 1.1 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.15 KKK19275.1 - 0.00024 21.1 6.6 0.00024 21.1 4.6 3.0 3 1 0 3 3 3 1 EamA-like transporter family Neurensin PF14927.1 KKK19275.1 - 0.2 11.0 4.5 2.7 7.3 0.6 3.0 2 1 0 2 2 2 0 Neurensin Multi_Drug_Res PF00893.14 KKK19275.1 - 0.88 10.0 13.5 2.8 8.4 1.4 3.1 2 2 1 3 3 3 0 Small Multidrug Resistance protein DUF3353 PF11833.3 KKK19275.1 - 7.7 5.9 8.3 2.4 7.5 0.9 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3353) vATP-synt_E PF01991.13 KKK19276.1 - 2.2e-59 200.0 12.2 2.6e-59 199.8 8.4 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit DUF4288 PF14119.1 KKK19276.1 - 0.51 10.5 3.2 36 4.5 0.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4288) E1-E2_ATPase PF00122.15 KKK19278.1 - 3.5e-12 45.8 0.0 3.5e-12 45.8 0.0 2.4 3 0 0 3 3 3 1 E1-E2 ATPase HAD PF12710.2 KKK19278.1 - 4.9e-12 46.4 0.1 9.7e-12 45.4 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KKK19278.1 - 2.8e-11 44.2 0.5 5.3e-10 40.0 0.4 2.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KKK19278.1 - 3.3e-11 42.9 0.0 8.9e-11 41.5 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KKK19278.1 - 0.045 13.3 0.1 0.1 12.1 0.1 1.5 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase SEN1_N PF12726.2 KKK19279.1 - 7.1e-232 771.5 8.5 9e-232 771.1 5.9 1.1 1 0 0 1 1 1 1 SEN1 N terminal AAA_11 PF13086.1 KKK19279.1 - 1.1e-67 228.0 0.5 1.1e-67 228.0 0.4 2.6 4 0 0 4 4 4 1 AAA domain AAA_12 PF13087.1 KKK19279.1 - 1.8e-62 210.2 0.0 4.9e-62 208.8 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KKK19279.1 - 1e-10 41.1 0.4 3.4e-10 39.5 0.3 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 KKK19279.1 - 1.3e-08 34.6 0.2 1.3e-05 24.8 0.1 2.5 2 0 0 2 2 2 2 AAA domain UvrD-helicase PF00580.16 KKK19279.1 - 1e-06 28.3 1.0 6.8e-06 25.5 0.1 2.6 2 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain Viral_helicase1 PF01443.13 KKK19279.1 - 3.9e-06 26.5 0.2 0.069 12.6 0.0 3.5 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase DEAD PF00270.24 KKK19279.1 - 0.00011 21.7 0.4 0.0019 17.6 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase zf-CCHC PF00098.18 KKK19279.1 - 0.0013 18.5 11.0 0.0057 16.5 1.4 2.7 2 0 0 2 2 2 2 Zinc knuckle AAA_25 PF13481.1 KKK19279.1 - 0.0072 15.7 0.0 0.018 14.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain ResIII PF04851.10 KKK19279.1 - 0.014 15.2 0.0 0.072 12.9 0.0 2.3 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA PF00004.24 KKK19279.1 - 0.067 13.4 0.2 0.35 11.0 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) zf-CCHC_3 PF13917.1 KKK19279.1 - 0.19 11.5 19.2 1.1 9.0 1.2 4.1 1 1 2 3 3 3 0 Zinc knuckle AAA_23 PF13476.1 KKK19279.1 - 0.28 11.4 0.0 0.28 11.4 0.0 2.5 3 0 0 3 3 2 0 AAA domain HMA PF00403.21 KKK19309.1 - 0.00015 21.8 0.1 0.00015 21.7 0.1 1.1 1 0 0 1 1 1 1 Heavy-metal-associated domain L31 PF09784.4 KKK19332.1 - 3.2e-47 158.8 1.9 3.6e-47 158.6 1.3 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 DEAD PF00270.24 KKK19334.1 - 1.2e-40 138.7 0.1 2.3e-40 137.8 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KKK19334.1 - 4.2e-22 77.8 0.0 2.7e-11 43.1 0.0 3.2 3 0 0 3 3 3 2 Helicase conserved C-terminal domain p450 PF00067.17 KKK19335.1 - 3.2e-68 230.3 0.0 3.8e-68 230.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Acyltransferase PF01553.16 KKK19336.1 - 7.9e-13 47.9 0.0 1.4e-12 47.2 0.0 1.4 1 1 0 1 1 1 1 Acyltransferase PsbL PF02419.12 KKK19337.1 - 0.21 11.0 1.7 0.4 10.1 1.2 1.4 1 0 0 1 1 1 0 PsbL protein Pkinase PF00069.20 KKK19341.1 - 1e-64 218.2 0.0 1.2e-64 217.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK19341.1 - 7.7e-26 90.7 0.0 9.5e-26 90.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KKK19341.1 - 5.2e-07 28.9 0.0 2.1e-06 26.9 0.0 1.9 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 KKK19341.1 - 0.0041 16.8 0.1 0.021 14.5 0.0 2.0 2 1 1 3 3 3 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KKK19341.1 - 0.12 11.9 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase MIF4G_like PF09088.6 KKK19342.1 - 3.3e-83 277.8 0.0 6.1e-83 276.9 0.0 1.5 1 0 0 1 1 1 1 MIF4G like MIF4G_like_2 PF09090.6 KKK19342.1 - 5.3e-64 215.8 0.0 7.9e-64 215.3 0.0 1.3 1 0 0 1 1 1 1 MIF4G like cobW PF02492.14 KKK19359.1 - 4.6e-34 117.3 0.0 5.6e-34 117.1 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain ArgK PF03308.11 KKK19359.1 - 5.9e-06 25.2 1.3 0.00011 21.1 0.9 2.0 1 1 0 1 1 1 1 ArgK protein MMR_HSR1 PF01926.18 KKK19359.1 - 0.0057 16.5 0.0 0.01 15.8 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_17 PF13207.1 KKK19359.1 - 0.006 17.3 0.0 0.0098 16.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KKK19359.1 - 0.0086 16.3 0.0 0.015 15.5 0.0 1.6 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.8 KKK19359.1 - 0.02 13.6 0.0 0.029 13.0 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus AAA_5 PF07728.9 KKK19359.1 - 0.023 14.4 0.0 0.033 13.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) GTP_EFTU PF00009.22 KKK19359.1 - 0.03 13.7 0.0 2.8 7.3 0.0 2.4 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain IstB_IS21 PF01695.12 KKK19359.1 - 0.038 13.4 0.0 0.095 12.1 0.0 1.6 2 0 0 2 2 2 0 IstB-like ATP binding protein CbiA PF01656.18 KKK19359.1 - 0.042 13.2 0.1 0.06 12.7 0.0 1.2 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain PRK PF00485.13 KKK19359.1 - 0.073 12.6 0.0 0.27 10.7 0.0 1.8 1 1 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Zeta_toxin PF06414.7 KKK19359.1 - 0.082 11.9 0.0 0.21 10.6 0.0 1.6 2 0 0 2 2 2 0 Zeta toxin NACHT PF05729.7 KKK19359.1 - 0.093 12.3 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 NACHT domain MobB PF03205.9 KKK19359.1 - 0.15 11.7 0.0 0.99 9.1 0.0 2.2 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B KAP_NTPase PF07693.9 KKK19359.1 - 0.15 11.0 0.0 0.15 11.0 0.0 1.1 1 0 0 1 1 1 0 KAP family P-loop domain DLH PF01738.13 KKK19362.1 - 1.5e-10 40.7 0.0 1.9e-10 40.4 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family HP_OMP_2 PF02521.9 KKK19362.1 - 0.014 14.0 0.3 0.021 13.4 0.2 1.2 1 0 0 1 1 1 0 Putative outer membrane protein DUF221 PF02714.10 KKK19363.1 - 7.6e-113 376.6 27.4 6.1e-111 370.3 12.5 2.9 3 0 0 3 3 3 2 Domain of unknown function DUF221 RSN1_TM PF13967.1 KKK19363.1 - 8.9e-46 155.3 3.9 8.9e-46 155.3 2.7 2.6 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 KKK19363.1 - 2.8e-33 113.6 0.5 6.3e-33 112.5 0.1 1.7 2 0 0 2 2 2 1 Phosphate metabolism protein DUF4463 PF14703.1 KKK19363.1 - 1.5e-21 76.6 0.3 2.8e-21 75.7 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) Baculo_E56 PF04639.7 KKK19363.1 - 0.16 10.6 0.0 0.16 10.6 0.0 1.8 2 0 0 2 2 2 0 Baculoviral E56 protein, specific to ODV envelope Amnionless PF14828.1 KKK19363.1 - 0.22 9.9 0.0 6.9 5.0 0.0 2.2 2 0 0 2 2 2 0 Amnionless DUF4519 PF15012.1 KKK19363.1 - 2.4 8.1 7.0 1.1 9.2 0.0 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4519) Rifin_STEVOR PF02009.11 KKK19363.1 - 8.1 5.9 7.3 54 3.2 0.0 2.9 3 0 0 3 3 3 0 Rifin/stevor family DUF912 PF06024.7 KKK19363.1 - 8.4 6.5 10.6 7.3 6.7 0.0 3.6 2 1 1 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) MCM PF00493.18 KKK19364.1 - 1.5e-131 438.1 0.1 2.3e-131 437.5 0.1 1.3 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 KKK19364.1 - 4.8e-19 69.0 0.1 4.8e-19 69.0 0.1 2.4 2 1 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 KKK19364.1 - 2.4e-05 23.5 0.0 0.00025 20.2 0.0 2.4 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 KKK19364.1 - 0.0029 17.0 0.0 0.0063 16.0 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.9 KKK19364.1 - 0.0031 17.2 0.0 0.0086 15.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 KKK19364.1 - 0.0052 16.3 0.0 0.021 14.4 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Npa1 PF11707.3 KKK19366.1 - 3.8e-106 354.8 0.2 7.9e-106 353.7 0.1 1.6 1 0 0 1 1 1 1 Ribosome 60S biogenesis N-terminal Creb_binding PF09030.5 KKK19366.1 - 0.011 15.8 0.0 0.05 13.7 0.0 2.2 2 0 0 2 2 2 0 Creb binding Arm PF00514.18 KKK19366.1 - 0.072 12.9 0.0 1.6 8.7 0.0 3.0 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat DUF1365 PF07103.6 KKK19367.1 - 5.5e-15 55.1 0.0 9.3e-10 37.9 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1365) Pyr_redox_3 PF13738.1 KKK19368.1 - 8.6e-25 87.9 0.0 1.4e-23 84.0 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KKK19368.1 - 2e-12 46.1 0.1 1.3e-10 40.0 0.2 2.8 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 KKK19368.1 - 3.8e-11 42.8 0.0 1e-10 41.4 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 KKK19368.1 - 7.1e-09 35.6 0.0 4.6e-05 23.2 0.0 2.5 2 0 0 2 2 2 2 FAD-NAD(P)-binding K_oxygenase PF13434.1 KKK19368.1 - 3.5e-07 29.4 0.0 0.0044 15.9 0.0 3.1 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 KKK19368.1 - 6.7e-07 29.3 0.0 0.0018 18.2 0.0 2.8 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KKK19368.1 - 7.6e-06 25.0 0.1 0.0005 19.0 0.0 2.7 2 1 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KKK19368.1 - 0.0013 19.1 0.0 0.068 13.5 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 KKK19368.1 - 0.0022 17.1 0.0 0.11 11.6 0.0 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Thi4 PF01946.12 KKK19368.1 - 0.012 14.7 0.0 0.027 13.5 0.0 1.5 2 0 0 2 2 2 0 Thi4 family GIDA PF01134.17 KKK19368.1 - 0.029 13.2 0.0 3.2 6.5 0.0 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A Shikimate_DH PF01488.15 KKK19368.1 - 0.049 13.7 0.0 7.6 6.6 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Lycopene_cycl PF05834.7 KKK19368.1 - 0.085 11.7 0.0 0.27 10.0 0.0 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_binding_2 PF00890.19 KKK19368.1 - 0.097 11.4 0.0 0.17 10.6 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Malate_synthase PF01274.17 KKK19369.1 - 1.3e-186 620.6 0.0 1.5e-186 620.4 0.0 1.0 1 0 0 1 1 1 1 Malate synthase COX16 PF14138.1 KKK19384.1 - 1.3e-30 105.3 0.2 1.6e-30 105.0 0.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 SDP_N PF12278.3 KKK19384.1 - 0.025 14.2 2.4 0.035 13.7 1.7 1.1 1 0 0 1 1 1 0 Sex determination protein N terminal Nic96 PF04097.9 KKK19385.1 - 9.6e-210 697.8 0.0 1.1e-209 697.5 0.0 1.0 1 0 0 1 1 1 1 Nup93/Nic96 Nucleoporin_FG PF13634.1 KKK19385.1 - 3.4e-06 27.2 28.4 3.4e-06 27.2 19.7 2.4 2 0 0 2 2 2 1 Nucleoporin FG repeat region F-box PF00646.28 KKK19386.1 - 0.031 13.9 0.0 0.08 12.6 0.0 1.6 1 0 0 1 1 1 0 F-box domain HTH_AraC PF00165.18 KKK19386.1 - 0.047 13.5 1.1 0.15 11.9 0.8 1.9 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix proteins, AraC family F-box-like_2 PF13013.1 KKK19386.1 - 0.055 13.1 0.3 1 9.0 0.1 2.6 3 0 0 3 3 3 0 F-box-like domain Y_phosphatase PF00102.22 KKK19387.1 - 1.2e-60 204.8 5.6 1.6e-60 204.3 0.0 3.0 2 1 0 2 2 2 1 Protein-tyrosine phosphatase Rhodanese PF00581.15 KKK19387.1 - 7.5e-12 45.6 0.0 3.5e-10 40.2 0.0 2.7 2 0 0 2 2 2 1 Rhodanese-like domain DSPc PF00782.15 KKK19387.1 - 0.0011 18.5 0.0 0.0033 17.0 0.0 1.7 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 KKK19387.1 - 0.01 16.1 2.1 0.014 15.6 0.0 2.3 2 0 0 2 2 2 0 Tyrosine phosphatase family RibD_C PF01872.12 KKK19389.1 - 2.9e-30 105.4 0.0 4.3e-30 104.8 0.0 1.3 1 0 0 1 1 1 1 RibD C-terminal domain PAT1 PF09770.4 KKK19389.1 - 0.24 9.6 17.7 0.33 9.1 12.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Pex14_N PF04695.8 KKK19389.1 - 0.84 9.6 8.4 2.1 8.4 5.8 1.6 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF605 PF04652.11 KKK19389.1 - 1.1 8.5 20.7 1.7 7.9 14.4 1.2 1 0 0 1 1 1 0 Vta1 like Lin-8 PF03353.10 KKK19389.1 - 2.5 7.3 6.9 3.6 6.7 4.8 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist RCC1 PF00415.13 KKK19390.1 - 1.7e-60 200.9 11.1 3.2e-12 46.4 0.1 7.9 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 KKK19390.1 - 5.1e-33 111.9 40.9 2.9e-09 36.3 0.9 6.8 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat SUKH_5 PF14567.1 KKK19390.1 - 0.12 11.8 0.0 19 4.7 0.0 3.5 4 0 0 4 4 4 0 SMI1-KNR4 cell-wall uDENN PF03456.13 KKK19390.1 - 0.13 12.2 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 uDENN domain AA_permease PF00324.16 KKK19392.1 - 1.1e-106 357.0 40.2 1.3e-106 356.8 27.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KKK19392.1 - 1.9e-28 99.1 42.7 2.5e-28 98.7 29.6 1.1 1 0 0 1 1 1 1 Amino acid permease Trp_oprn_chp PF09534.5 KKK19392.1 - 0.31 10.6 9.9 0.28 10.7 0.1 2.8 2 1 1 3 3 3 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Pox_P21 PF05313.7 KKK19392.1 - 10 5.3 8.2 2.8 7.1 2.9 2.0 2 0 0 2 2 2 0 Poxvirus P21 membrane protein Glyco_hydro_2_N PF02837.13 KKK19393.1 - 1.4e-12 47.5 0.0 7.4e-12 45.1 0.1 2.2 2 1 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.16 KKK19393.1 - 1.5e-11 44.7 0.1 4.4e-11 43.2 0.1 1.9 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Glyco_hydro_2_C PF02836.12 KKK19393.1 - 3.6e-05 22.8 0.1 6.9e-05 21.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Mannosyl_trans PF05007.8 KKK19394.1 - 1.6e-72 244.2 9.3 1.7e-57 195.0 6.9 2.4 2 0 0 2 2 2 2 Mannosyltransferase (PIG-M) Fungal_trans PF04082.13 KKK19394.1 - 5.4e-23 81.1 0.5 1e-22 80.3 0.4 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain PIG-U PF06728.8 KKK19394.1 - 2.4e-11 43.1 0.7 2.4e-11 43.1 0.5 2.0 2 0 0 2 2 2 1 GPI transamidase subunit PIG-U DUF2029 PF09594.5 KKK19394.1 - 1.3e-06 28.1 7.0 1.3e-06 28.1 4.8 3.6 3 0 0 3 3 3 2 Protein of unknown function (DUF2029) Zn_clus PF00172.13 KKK19394.1 - 1.3e-05 25.0 12.9 2.2e-05 24.2 8.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Kinesin PF00225.18 KKK19395.1 - 5.8e-112 373.7 1.9 1.6e-111 372.2 1.3 1.8 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bind PF13931.1 KKK19395.1 - 2.9e-09 37.1 0.4 2.9e-09 37.1 0.3 5.9 3 2 2 5 5 5 1 Kinesin-associated microtubule-binding Baculo_PEP_C PF04513.7 KKK19395.1 - 0.00026 20.8 32.0 0.0003 20.6 0.1 5.8 1 1 2 5 5 5 3 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1515 PF07439.6 KKK19395.1 - 0.9 9.3 15.8 0.25 11.1 1.4 4.9 3 3 0 3 3 3 0 Protein of unknown function (DUF1515) UPF0183 PF03676.9 KKK19396.1 - 1.5e-35 122.5 0.0 1e-24 86.9 0.0 3.7 3 1 0 3 3 3 3 Uncharacterised protein family (UPF0183) zf-Apc11 PF12861.2 KKK19397.1 - 6.4e-47 157.3 10.6 7.2e-47 157.1 7.4 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 KKK19397.1 - 4e-32 110.1 8.9 4.7e-32 109.9 6.2 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 KKK19397.1 - 6.3e-08 32.3 18.4 4.4e-07 29.6 12.6 2.5 1 1 1 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 KKK19397.1 - 1.4e-05 24.6 11.9 0.0009 18.8 8.5 2.4 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KKK19397.1 - 0.00028 20.8 14.8 0.0033 17.4 10.2 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 KKK19397.1 - 0.00048 19.6 11.8 0.022 14.3 6.2 2.6 1 1 1 2 2 2 1 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 KKK19397.1 - 0.00094 19.0 2.0 0.00094 19.0 1.4 2.3 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 KKK19397.1 - 0.00099 18.7 15.3 0.0077 15.9 10.8 2.4 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KKK19397.1 - 0.001 18.6 13.8 0.0038 16.8 9.5 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 KKK19397.1 - 0.0014 18.5 15.6 0.032 14.1 10.8 3.1 1 1 0 1 1 1 1 FANCL C-terminal domain zf-HIT PF04438.11 KKK19397.1 - 0.017 14.7 3.5 0.05 13.2 0.4 2.4 2 0 0 2 2 2 0 HIT zinc finger zf-RING_3 PF14369.1 KKK19397.1 - 0.057 13.4 2.7 8.1 6.5 0.1 3.2 3 0 0 3 3 3 0 zinc-finger zf-RING_UBOX PF13445.1 KKK19397.1 - 0.13 11.9 7.2 0.23 11.1 3.1 2.4 1 1 1 2 2 2 0 RING-type zinc-finger DUF2256 PF10013.4 KKK19397.1 - 0.13 11.9 0.4 0.13 11.9 0.3 3.4 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-DBF PF07535.7 KKK19397.1 - 0.14 11.8 4.1 0.92 9.2 0.1 2.3 2 0 0 2 2 2 0 DBF zinc finger zf-RING-like PF08746.6 KKK19397.1 - 0.23 11.5 11.9 1.4 9.0 8.2 2.2 1 1 0 1 1 1 0 RING-like domain zf-Nse PF11789.3 KKK19397.1 - 0.35 10.4 6.0 0.76 9.3 4.2 1.7 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit PHD PF00628.24 KKK19397.1 - 0.4 10.4 13.4 1.7 8.4 9.3 2.0 1 1 0 1 1 1 0 PHD-finger DUF329 PF03884.9 KKK19397.1 - 0.48 10.0 0.1 0.48 10.0 0.1 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF329) RecR PF02132.10 KKK19397.1 - 0.79 9.2 4.2 5.5 6.5 0.1 3.0 3 0 0 3 3 3 0 RecR protein Opy2 PF09463.5 KKK19397.1 - 1 9.4 8.9 2.2 8.4 3.4 2.2 2 0 0 2 2 2 0 Opy2 protein DZR PF12773.2 KKK19397.1 - 1.2 8.9 11.1 29 4.5 7.7 2.2 1 1 0 1 1 1 0 Double zinc ribbon RINGv PF12906.2 KKK19397.1 - 8.8 6.4 14.4 18 5.5 9.1 2.2 1 1 1 2 2 2 0 RING-variant domain Rhodanese PF00581.15 KKK19399.1 - 1.2e-18 67.4 0.0 1.6e-09 38.1 0.0 2.2 2 0 0 2 2 2 2 Rhodanese-like domain Bac_rhodopsin PF01036.13 KKK19400.1 - 1.9e-33 115.6 15.3 2.2e-33 115.4 10.6 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein PIN_4 PF13638.1 KKK19401.1 - 0.0015 18.6 0.1 0.054 13.5 0.1 2.5 2 1 0 2 2 2 2 PIN domain Translin PF01997.11 KKK19402.1 - 7e-70 234.6 0.0 8.2e-70 234.4 0.0 1.0 1 0 0 1 1 1 1 Translin family RPEL PF02755.10 KKK19403.1 - 3.9e-19 67.3 7.9 5.7e-11 41.3 1.3 2.5 2 0 0 2 2 2 2 RPEL repeat PBP_sp32 PF07222.7 KKK19403.1 - 0.035 13.2 3.3 0.034 13.3 2.3 1.1 1 0 0 1 1 1 0 Proacrosin binding protein sp32 tRNA-synt_1 PF00133.17 KKK19404.1 - 2.1e-167 557.7 0.0 2.8e-167 557.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 KKK19404.1 - 1e-22 80.5 1.0 1.9e-22 79.6 0.7 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 KKK19404.1 - 4.6e-22 78.2 0.0 1.1e-12 47.3 0.0 4.0 3 1 0 3 3 3 3 tRNA synthetases class I (M) zf-FPG_IleRS PF06827.9 KKK19404.1 - 0.00032 20.2 3.6 0.00054 19.5 1.8 2.0 2 0 0 2 2 2 1 Zinc finger found in FPG and IleRS tRNA-synt_1d PF00750.14 KKK19404.1 - 0.018 13.8 0.0 0.094 11.5 0.0 1.9 2 0 0 2 2 2 0 tRNA synthetases class I (R) tRNA-synt_1_2 PF13603.1 KKK19404.1 - 0.043 13.1 0.0 0.081 12.2 0.0 1.3 1 0 0 1 1 1 0 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.14 KKK19404.1 - 0.066 12.3 0.0 7.9 5.4 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain TF_Zn_Ribbon PF08271.7 KKK19404.1 - 0.13 11.5 1.0 0.25 10.6 0.7 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding Exo_endo_phos PF03372.18 KKK19429.1 - 4.7e-20 72.5 0.1 7.5e-20 71.9 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_8 PF13855.1 KKK19429.1 - 7.9e-16 57.5 21.2 2.8e-08 33.3 3.1 2.2 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.2 KKK19429.1 - 5.9e-15 54.4 7.1 4.5e-10 38.9 1.1 2.5 1 1 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KKK19429.1 - 8.8e-07 28.1 4.7 0.032 14.2 0.1 4.3 4 0 0 4 4 4 2 Leucine Rich Repeat LRR_7 PF13504.1 KKK19429.1 - 6.8e-05 22.4 10.0 0.019 15.0 0.2 4.4 4 0 0 4 4 4 2 Leucine rich repeat Glyco_tran_28_C PF04101.11 KKK19450.1 - 7.7e-17 61.4 0.0 6.5e-14 51.9 0.0 2.1 2 0 0 2 2 2 2 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.1 KKK19450.1 - 3.7e-05 23.0 0.0 5.5e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 1 UDPGT PF00201.13 KKK19450.1 - 0.026 13.0 0.0 0.035 12.6 0.0 1.1 1 0 0 1 1 1 0 UDP-glucoronosyl and UDP-glucosyl transferase Actin PF00022.14 KKK19451.1 - 6.6e-134 446.2 0.0 7.5e-134 446.0 0.0 1.0 1 0 0 1 1 1 1 Actin DUF3602 PF12223.3 KKK19452.1 - 1.2e-17 64.0 5.4 2.4e-15 56.6 0.6 2.6 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) zf-U1 PF06220.7 KKK19453.1 - 2.1e-16 59.1 2.3 2.7e-16 58.8 1.6 1.2 1 0 0 1 1 1 1 U1 zinc finger Coatomer_E PF04733.9 KKK19453.1 - 0.11 11.7 0.0 0.12 11.5 0.0 1.0 1 0 0 1 1 1 0 Coatomer epsilon subunit SpoU_methylase PF00588.14 KKK19454.1 - 2e-25 89.3 0.0 1.7e-24 86.3 0.0 2.2 1 1 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.7 KKK19454.1 - 7.9e-08 32.3 0.0 1.6e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding zf-PHD-like PF15446.1 KKK19455.1 - 5.9e-66 221.0 9.5 1.3e-65 219.8 6.6 1.6 1 0 0 1 1 1 1 PHD/FYVE-zinc-finger like domain SNF2_N PF00176.18 KKK19455.1 - 7.6e-58 195.6 0.1 1.4e-57 194.8 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain HDA2-3 PF11496.3 KKK19455.1 - 8.2e-13 47.8 2.4 1.6e-12 46.8 1.7 1.4 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Helicase_C PF00271.26 KKK19455.1 - 9.6e-13 47.8 0.0 2.4e-12 46.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Chromo PF00385.19 KKK19455.1 - 9.4e-12 44.4 1.5 1.7e-06 27.5 0.4 3.0 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain PHD PF00628.24 KKK19455.1 - 8.7e-06 25.3 3.5 8.7e-06 25.3 2.4 3.4 2 1 1 3 3 3 1 PHD-finger DEAD PF00270.24 KKK19455.1 - 0.00012 21.6 0.0 0.0005 19.6 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 KKK19455.1 - 0.00019 21.3 0.0 0.0092 15.8 0.0 3.4 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit C1_1 PF00130.17 KKK19455.1 - 0.0044 16.7 9.7 0.025 14.2 1.3 3.7 3 0 0 3 3 3 1 Phorbol esters/diacylglycerol binding domain (C1 domain) AAA_22 PF13401.1 KKK19455.1 - 0.11 12.6 0.0 0.71 10.0 0.0 2.5 2 2 0 2 2 2 0 AAA domain PHD_2 PF13831.1 KKK19455.1 - 0.52 9.6 13.2 0.048 12.9 3.5 3.2 2 1 0 2 2 2 0 PHD-finger MRP-S28 PF10213.4 KKK19457.1 - 7.4e-45 152.1 0.0 1.4e-44 151.2 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein DUF3006 PF11213.3 KKK19457.1 - 0.18 11.5 2.1 0.9 9.3 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3006) Velvet PF11754.3 KKK19458.1 - 3.9e-39 134.3 0.2 7.9e-38 130.1 0.1 2.8 1 1 0 1 1 1 1 Velvet factor HMG_box PF00505.14 KKK19460.1 - 7.8e-23 80.5 1.5 1.5e-22 79.6 1.1 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KKK19460.1 - 2.3e-08 34.2 0.6 5.5e-08 33.0 0.4 1.6 1 0 0 1 1 1 1 HMG-box domain Lipase_GDSL PF00657.17 KKK19461.1 - 1.3e-07 31.7 0.0 2.5e-07 30.7 0.0 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase AAA_17 PF13207.1 KKK19462.1 - 2.1e-06 28.5 0.0 0.00032 21.5 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KKK19462.1 - 0.00036 20.8 0.0 0.0048 17.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain PRK PF00485.13 KKK19462.1 - 0.0081 15.7 0.0 0.016 14.8 0.0 1.4 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family ABC_tran PF00005.22 KKK19462.1 - 0.042 14.1 0.0 0.078 13.2 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_21 PF13304.1 KKK19462.1 - 0.051 13.5 0.1 0.069 13.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain CPT PF07931.7 KKK19462.1 - 0.069 12.7 0.1 0.19 11.3 0.0 1.7 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Mg_chelatase PF01078.16 KKK19462.1 - 0.11 11.6 0.0 0.2 10.8 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_16 PF13191.1 KKK19462.1 - 0.11 12.4 0.7 0.35 10.8 0.5 1.9 1 1 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.1 KKK19462.1 - 0.16 11.8 0.9 0.46 10.3 0.6 1.8 1 1 0 1 1 1 0 AAA domain Shadoo PF14999.1 KKK19462.1 - 0.59 9.9 8.4 1.1 9.1 5.8 1.4 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective SNF2_N PF00176.18 KKK19463.1 - 7.6e-32 110.2 0.0 5.7e-29 100.8 0.0 2.2 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.26 KKK19463.1 - 0.00054 19.7 0.0 0.001 18.8 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Ribosomal_S6e PF01092.14 KKK19464.1 - 2.5e-57 191.9 0.6 4.4e-57 191.2 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein S6e UFD1 PF03152.9 KKK19468.1 - 8e-77 256.3 0.0 1e-76 256.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 Oxidored_FMN PF00724.15 KKK19469.1 - 8.2e-63 212.4 0.0 2.5e-61 207.5 0.0 2.2 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family GYF PF02213.11 KKK19470.1 - 5.9e-13 48.2 0.5 1.3e-12 47.1 0.3 1.6 1 0 0 1 1 1 1 GYF domain TIP49 PF06068.8 KKK19471.1 - 9.7e-174 577.7 3.2 1.1e-173 577.5 2.2 1.0 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 KKK19471.1 - 8.5e-09 35.6 1.4 1.3e-05 25.4 0.0 2.9 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 KKK19471.1 - 1.9e-07 30.4 1.3 5.8e-05 22.2 0.0 2.6 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus DnaB_C PF03796.10 KKK19471.1 - 6e-06 25.3 0.4 1e-05 24.6 0.3 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_16 PF13191.1 KKK19471.1 - 1.4e-05 25.1 0.0 0.0003 20.8 0.0 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KKK19471.1 - 7e-05 22.9 0.0 0.075 13.1 0.0 2.5 1 1 1 2 2 2 2 AAA domain Mg_chelatase PF01078.16 KKK19471.1 - 0.00074 18.7 0.9 0.01 15.0 0.3 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 KKK19471.1 - 0.00098 19.0 0.0 1.8 8.4 0.0 2.9 2 1 1 3 3 3 2 AAA domain AAA_5 PF07728.9 KKK19471.1 - 0.0028 17.3 0.1 0.37 10.5 0.0 2.9 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 KKK19471.1 - 0.0098 15.3 0.4 0.029 13.7 0.1 1.9 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.21 KKK19471.1 - 0.012 15.0 0.1 5 6.5 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_19 PF13245.1 KKK19471.1 - 0.047 13.4 2.6 0.087 12.5 0.2 2.5 3 1 0 3 3 2 0 Part of AAA domain Parvo_NS1 PF01057.12 KKK19471.1 - 0.069 12.0 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_11 PF13086.1 KKK19471.1 - 0.089 12.3 0.2 0.22 11.0 0.1 1.4 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.1 KKK19471.1 - 0.13 12.2 0.0 0.32 10.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain Abhydrolase_6 PF12697.2 KKK19472.1 - 1.2e-29 103.7 0.0 1.5e-29 103.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KKK19472.1 - 2.7e-16 59.8 0.1 2.8e-15 56.4 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KKK19472.1 - 2.5e-15 56.4 0.0 3.9e-15 55.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 KKK19472.1 - 1.2e-09 38.1 0.1 1.7e-09 37.6 0.1 1.2 1 0 0 1 1 1 1 PGAP1-like protein Thioesterase PF00975.15 KKK19472.1 - 0.00019 21.7 0.0 0.00022 21.5 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain DUF915 PF06028.6 KKK19472.1 - 0.00068 18.7 0.1 1.4 7.9 0.1 2.7 2 1 1 3 3 3 2 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_3 PF07859.8 KKK19472.1 - 0.00079 19.0 0.0 0.001 18.7 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.15 KKK19472.1 - 0.0017 17.8 0.0 0.0045 16.4 0.0 1.8 1 1 0 1 1 1 1 Putative esterase Chlorophyllase PF07224.6 KKK19472.1 - 0.0056 15.5 0.1 0.013 14.3 0.0 1.7 1 1 0 1 1 1 1 Chlorophyllase DUF676 PF05057.9 KKK19472.1 - 0.0066 15.7 0.1 0.01 15.1 0.1 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) DUF2048 PF09752.4 KKK19472.1 - 0.022 13.6 0.0 0.13 11.0 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2048) UPF0227 PF05728.7 KKK19472.1 - 0.027 14.1 0.0 0.04 13.6 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Lipase_3 PF01764.20 KKK19472.1 - 0.03 13.9 0.0 0.047 13.2 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_2 PF02230.11 KKK19472.1 - 0.048 13.0 0.0 11 5.4 0.0 2.3 1 1 0 2 2 2 0 Phospholipase/Carboxylesterase Ndr PF03096.9 KKK19472.1 - 0.058 11.8 0.0 0.12 10.8 0.0 1.6 2 0 0 2 2 2 0 Ndr family LCAT PF02450.10 KKK19472.1 - 0.11 11.4 0.1 0.16 10.9 0.1 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DLH PF01738.13 KKK19472.1 - 0.13 11.5 0.0 1.3 8.2 0.0 2.3 2 1 0 2 2 2 0 Dienelactone hydrolase family DUF2764 PF10962.3 KKK19473.1 - 0.059 12.5 0.0 0.096 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2764) RS4NT PF08071.7 KKK19473.1 - 0.19 11.6 0.8 4.2 7.3 0.3 2.4 2 0 0 2 2 2 0 RS4NT (NUC023) domain adh_short PF00106.20 KKK19474.1 - 3.3e-17 62.8 0.1 5.7e-17 62.1 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KKK19474.1 - 2.2e-12 47.2 0.0 5.9e-12 45.8 0.0 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KKK19474.1 - 0.00022 20.7 0.0 0.00028 20.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 KKK19474.1 - 0.00041 20.0 0.1 0.0012 18.5 0.0 1.8 1 1 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 KKK19474.1 - 0.0013 18.4 0.0 0.0034 17.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase ADH_zinc_N PF00107.21 KKK19474.1 - 0.017 14.6 0.1 0.089 12.3 0.0 2.1 2 0 0 2 2 2 0 Zinc-binding dehydrogenase Exo_endo_phos PF03372.18 KKK19474.1 - 0.082 12.8 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family 2-Hacid_dh_C PF02826.14 KKK19474.1 - 0.12 11.5 0.0 0.21 10.7 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain RNA_pol_Rpb2_6 PF00562.23 KKK19475.1 - 7.4e-116 387.0 0.0 1.2e-115 386.4 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 KKK19475.1 - 1.4e-53 180.9 0.7 1.4e-53 180.9 0.5 1.7 2 0 0 2 2 2 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 KKK19475.1 - 3.1e-22 78.9 4.7 7.3e-22 77.7 3.3 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_4 PF04566.8 KKK19475.1 - 7.5e-21 73.7 1.5 3.2e-20 71.7 0.3 2.5 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.11 KKK19475.1 - 7.7e-20 70.4 0.3 3.1e-19 68.5 0.0 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_7 PF04560.15 KKK19475.1 - 3.5e-14 52.8 0.2 1.1e-13 51.1 0.1 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_5 PF04567.12 KKK19475.1 - 4.9e-12 45.6 0.2 1.1e-11 44.5 0.2 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Sugar_tr PF00083.19 KKK19476.1 - 9.8e-79 265.0 27.0 2.6e-65 220.7 7.9 2.8 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 KKK19476.1 - 1.1e-24 86.7 32.8 2.9e-10 39.4 3.7 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily OATP PF03137.15 KKK19476.1 - 1.5e-05 23.3 3.6 0.0023 16.0 1.5 2.7 2 1 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family MFS_1_like PF12832.2 KKK19476.1 - 0.00077 19.2 1.0 0.022 14.5 0.0 2.7 2 0 0 2 2 2 1 MFS_1 like family DUF676 PF05057.9 KKK19482.1 - 2.6e-41 141.3 0.0 9.5e-37 126.3 0.0 3.2 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Lipase_3 PF01764.20 KKK19482.1 - 0.0032 17.0 0.0 0.0072 15.9 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.8 KKK19482.1 - 0.014 15.0 0.0 0.027 14.0 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_5 PF12695.2 KKK19482.1 - 0.038 13.7 0.0 0.084 12.6 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF915 PF06028.6 KKK19482.1 - 0.049 12.7 0.0 0.093 11.8 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) LCAT PF02450.10 KKK19482.1 - 0.21 10.4 0.0 0.37 9.6 0.0 1.3 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Baculo_VP91_N PF08475.5 KKK19482.1 - 0.24 10.7 0.1 0.41 9.9 0.1 1.2 1 0 0 1 1 1 0 Viral capsid protein 91 N-terminal Inositol_P PF00459.20 KKK19483.1 - 7.6e-70 235.2 0.0 8.6e-70 235.1 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family TFIIF_alpha PF05793.7 KKK19484.1 - 1.4e-06 26.9 69.1 5.5e-06 25.0 40.0 4.1 1 1 2 3 3 3 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF383 PF04063.9 KKK19485.1 - 3.9e-74 248.3 0.6 1.6e-73 246.3 0.0 2.2 3 0 0 3 3 3 1 Domain of unknown function (DUF383) DUF384 PF04064.8 KKK19485.1 - 6.7e-24 83.2 1.1 1.3e-23 82.2 0.2 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF384) AsiA PF09010.5 KKK19485.1 - 0.0091 15.8 0.0 0.02 14.7 0.0 1.6 1 0 0 1 1 1 1 Anti-Sigma Factor A FUSC_2 PF13515.1 KKK19486.1 - 0.23 11.3 7.6 0.029 14.2 1.8 2.1 1 1 1 2 2 2 0 Fusaric acid resistance protein-like Melibiase PF02065.13 KKK19487.1 - 5.3e-155 515.9 0.0 6.5e-155 515.6 0.0 1.1 1 0 0 1 1 1 1 Melibiase DUF187 PF02638.10 KKK19487.1 - 0.00017 20.5 0.0 0.00027 19.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase like GH101 GMC_oxred_N PF00732.14 KKK19488.1 - 8.9e-61 205.6 0.0 1.2e-60 205.1 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KKK19488.1 - 7.7e-33 113.7 0.5 2.4e-32 112.1 0.1 2.0 2 0 0 2 2 2 1 GMC oxidoreductase Lycopene_cycl PF05834.7 KKK19488.1 - 0.00033 19.6 0.1 0.00059 18.8 0.1 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 KKK19488.1 - 0.00036 19.4 0.2 0.091 11.5 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 KKK19488.1 - 0.0012 17.8 0.5 0.0032 16.4 0.2 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KKK19488.1 - 0.04 13.9 0.2 0.095 12.7 0.1 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 KKK19488.1 - 0.051 13.6 0.0 3.2 7.7 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NHase_beta PF02211.10 KKK19488.1 - 0.092 12.4 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Nitrile hydratase beta subunit MFS_1 PF07690.11 KKK19489.1 - 1.7e-33 115.8 31.0 2.3e-33 115.3 21.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily 3HCDH_N PF02737.13 KKK19490.1 - 1.7e-26 92.9 0.0 2.6e-26 92.3 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 KKK19490.1 - 2.5e-19 69.4 0.0 3.9e-19 68.8 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain TrkA_N PF02254.13 KKK19490.1 - 0.0062 16.5 0.0 0.015 15.2 0.0 1.6 1 1 0 1 1 1 1 TrkA-N domain NAD_Gly3P_dh_N PF01210.18 KKK19490.1 - 0.032 13.9 0.0 0.073 12.8 0.0 1.6 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.11 KKK19490.1 - 0.052 12.9 0.0 0.087 12.2 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Glyco_hydro_31 PF01055.21 KKK19492.1 - 5.7e-85 285.7 0.6 1.2e-84 284.6 0.3 1.5 2 0 0 2 2 2 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 KKK19492.1 - 4.1e-15 55.3 0.0 1.1e-14 53.9 0.0 1.8 1 0 0 1 1 1 1 Galactose mutarotase-like MFS_1 PF07690.11 KKK19493.1 - 1.4e-29 102.9 29.5 2e-29 102.4 19.8 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Glyco_hydro_11 PF00457.12 KKK19495.1 - 6.1e-73 244.0 23.4 7.2e-73 243.8 16.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 Fungal_trans PF04082.13 KKK19496.1 - 1.3e-10 40.5 0.0 2.8e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK19496.1 - 1.3e-05 24.9 6.7 3e-05 23.8 4.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dioxygenase_C PF00775.16 KKK19497.1 - 8.9e-44 148.9 0.0 1.2e-43 148.5 0.0 1.1 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.9 KKK19497.1 - 5.7e-11 42.2 0.0 9.5e-11 41.5 0.0 1.3 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.1 KKK19497.1 - 0.12 12.4 0.0 0.44 10.6 0.0 1.9 2 1 0 2 2 2 0 Carboxypeptidase regulatory-like domain Abhydrolase_6 PF12697.2 KKK19498.1 - 1.1e-19 71.1 0.3 1.5e-19 70.7 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KKK19498.1 - 2.4e-09 37.0 0.0 2.9e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KKK19498.1 - 3.5e-06 26.8 0.0 5.5e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KKK19498.1 - 0.0029 17.4 0.0 0.0053 16.5 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase CTV_P6 PF06706.6 KKK19499.1 - 1.1 8.7 8.5 1.1 8.8 3.6 2.6 2 0 0 2 2 2 0 Citrus tristeza virus 6-kDa protein TPR_11 PF13414.1 KKK19507.1 - 1.7e-09 37.2 2.6 8.3e-07 28.5 0.2 2.6 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 KKK19507.1 - 3.2e-06 26.6 2.5 0.018 14.9 0.2 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 KKK19507.1 - 4.4e-06 26.0 1.1 0.054 13.1 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 KKK19507.1 - 0.021 15.5 0.3 0.021 15.5 0.2 2.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 KKK19507.1 - 0.1 12.4 1.6 11 6.0 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.1 KKK19507.1 - 0.11 12.7 0.3 1.1 9.6 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Fungal_trans PF04082.13 KKK19508.1 - 7e-14 51.3 0.0 1.2e-13 50.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF2841 PF11001.3 KKK19509.1 - 4.6e-46 155.7 0.8 7.7e-46 155.0 0.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) SSXT PF05030.7 KKK19510.1 - 0.0038 16.7 0.0 2 8.0 0.0 2.3 2 0 0 2 2 2 2 SSXT protein (N-terminal region) DUF2486 PF10667.4 KKK19510.1 - 2.7 8.4 10.7 4.4 7.7 7.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2486) Ribosomal_S13 PF00416.17 KKK19511.1 - 1.5e-12 47.8 0.1 1.7e-12 47.6 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 HHH_6 PF14579.1 KKK19511.1 - 0.046 13.7 0.0 0.046 13.7 0.0 1.1 1 0 0 1 1 1 0 Helix-hairpin-helix motif peroxidase PF00141.18 KKK19513.1 - 1.7e-47 161.8 0.0 2.4e-47 161.3 0.0 1.2 1 0 0 1 1 1 1 Peroxidase DUF1019 PF06254.6 KKK19514.1 - 0.026 14.6 0.1 0.052 13.7 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1019) PDZ_1 PF12812.2 KKK19515.1 - 9.8e-54 179.1 0.0 2.1e-33 114.0 0.0 2.6 2 0 0 2 2 2 2 PDZ-like domain Trypsin_2 PF13365.1 KKK19515.1 - 1.1e-14 54.4 0.2 6.1e-14 52.0 0.0 2.2 2 0 0 2 2 2 1 Trypsin-like peptidase domain PDZ_2 PF13180.1 KKK19515.1 - 2.2e-13 49.8 0.0 1.5e-05 24.7 0.0 4.1 4 0 0 4 4 4 3 PDZ domain PDZ PF00595.19 KKK19515.1 - 3.3e-12 46.4 0.0 3.4e-05 23.9 0.0 3.7 3 0 0 3 3 3 3 PDZ domain (Also known as DHR or GLGF) Tricorn_PDZ PF14685.1 KKK19515.1 - 0.00013 21.7 0.3 0.058 13.1 0.1 3.6 3 0 0 3 3 3 1 Tricorn protease PDZ domain Trypsin PF00089.21 KKK19515.1 - 0.00021 20.9 0.0 0.00075 19.1 0.0 1.9 1 1 0 1 1 1 1 Trypsin Peptidase_S7 PF00949.16 KKK19515.1 - 0.064 12.6 0.1 0.15 11.4 0.1 1.5 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease DUF31 PF01732.11 KKK19515.1 - 0.092 12.0 0.3 0.14 11.4 0.2 1.2 1 0 0 1 1 1 0 Putative peptidase (DUF31) Peptidase_S46 PF10459.4 KKK19515.1 - 0.23 9.8 0.5 0.35 9.2 0.1 1.4 2 0 0 2 2 2 0 Peptidase S46 Cyclase PF04199.8 KKK19516.1 - 2.1e-11 43.8 0.1 3.6e-11 43.0 0.0 1.5 1 0 0 1 1 1 1 Putative cyclase GFO_IDH_MocA PF01408.17 KKK19517.1 - 1.2e-25 90.3 0.8 1.5e-24 86.7 0.2 2.2 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.11 KKK19517.1 - 8.5e-05 22.9 0.1 0.00025 21.4 0.1 1.7 2 0 0 2 2 2 1 Homoserine dehydrogenase, NAD binding domain TFIID_30kDa PF03540.8 KKK19517.1 - 0.17 11.7 0.3 0.38 10.6 0.0 1.8 2 0 0 2 2 2 0 Transcription initiation factor TFIID 23-30kDa subunit K1 PF02960.9 KKK19518.1 - 0.015 15.3 0.1 0.035 14.1 0.0 1.6 1 1 0 1 1 1 0 K1 glycoprotein DUF3098 PF11297.3 KKK19518.1 - 0.078 12.7 0.4 0.078 12.7 0.3 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3098) PqiA PF04403.8 KKK19518.1 - 2.5 7.6 12.0 0.43 10.1 1.0 3.2 2 1 1 3 3 3 0 Paraquat-inducible protein A Vma12 PF11712.3 KKK19518.1 - 3.9 7.1 6.0 0.45 10.2 0.6 2.1 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Zn_clus PF00172.13 KKK19519.1 - 3.9e-06 26.6 10.6 9.2e-06 25.4 7.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GFO_IDH_MocA PF01408.17 KKK19520.1 - 1.3e-19 70.8 0.0 2.8e-19 69.7 0.0 1.5 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold Sugar_tr PF00083.19 KKK19521.1 - 8.5e-71 238.8 29.7 1.1e-70 238.5 20.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KKK19521.1 - 1.6e-21 76.4 44.8 4.5e-19 68.3 24.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily CrtC PF07143.6 KKK19522.1 - 1.9e-10 40.5 0.4 4.7e-10 39.2 0.2 1.6 1 1 0 1 1 1 1 Hydroxyneurosporene synthase (CrtC) PX PF00787.19 KKK19523.1 - 3.4e-18 65.4 0.4 9.3e-18 64.0 0.3 1.7 1 0 0 1 1 1 1 PX domain Prefoldin_3 PF13758.1 KKK19523.1 - 0.068 12.9 0.2 0.068 12.9 0.2 2.4 2 0 0 2 2 2 0 Prefoldin subunit Nha1_C PF08619.5 KKK19524.1 - 1.6e-96 324.2 20.4 3.3e-96 323.2 14.1 1.5 1 1 0 1 1 1 1 Alkali metal cation/H+ antiporter Nha1 C terminus Na_H_Exchanger PF00999.16 KKK19524.1 - 2.9e-69 233.4 17.5 3.7e-69 233.0 12.2 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF21 PF01595.15 KKK19524.1 - 0.83 8.9 10.6 0.061 12.6 2.4 2.3 2 0 0 2 2 2 0 Domain of unknown function DUF21 SAM_2 PF07647.12 KKK19525.1 - 4.4e-16 58.4 0.0 2.2e-15 56.2 0.0 2.0 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) RA PF00788.18 KKK19525.1 - 1.4e-14 54.2 0.0 3e-14 53.2 0.0 1.4 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SAM_1 PF00536.25 KKK19525.1 - 6.1e-12 45.5 0.0 2.1e-11 43.8 0.0 1.8 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) Angiomotin_C PF12240.3 KKK19525.1 - 0.048 13.1 0.2 0.084 12.3 0.2 1.3 1 0 0 1 1 1 0 Angiomotin C terminal Inositol_P PF00459.20 KKK19529.1 - 1.2e-38 133.0 0.1 2.1e-38 132.2 0.1 1.4 1 1 0 1 1 1 1 Inositol monophosphatase family Peptidase_M28 PF04389.12 KKK19531.1 - 7.3e-27 94.2 0.6 1.2e-26 93.5 0.4 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 KKK19531.1 - 1.8e-06 27.5 0.1 4e-06 26.4 0.1 1.6 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 R3H-assoc PF13902.1 KKK19532.1 - 7.9e-25 87.3 5.8 2.1e-24 85.9 4.1 1.8 1 1 0 1 1 1 1 R3H-associated N-terminal domain R3H PF01424.17 KKK19532.1 - 0.0031 17.1 0.6 0.0063 16.1 0.1 1.9 2 0 0 2 2 2 1 R3H domain PP2C PF00481.16 KKK19533.1 - 1e-51 175.8 0.0 1.8e-51 175.0 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_4 PF12799.2 KKK19533.1 - 1.2e-43 146.0 51.1 8e-08 31.7 0.2 11.9 7 3 4 11 11 11 9 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KKK19533.1 - 5.7e-36 122.0 52.7 4.4e-07 29.5 0.1 10.2 7 3 5 12 12 12 10 Leucine rich repeat Guanylate_cyc PF00211.15 KKK19533.1 - 8.5e-29 100.2 0.0 1.6e-28 99.3 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain LRR_1 PF00560.28 KKK19533.1 - 1.7e-14 51.6 60.4 0.087 12.9 0.1 17.2 16 3 1 17 17 17 8 Leucine Rich Repeat Ad_cyc_g-alpha PF08509.6 KKK19533.1 - 8e-11 41.1 0.1 2.5e-10 39.5 0.1 1.9 1 0 0 1 1 1 1 Adenylate cyclase G-alpha binding domain LRR_7 PF13504.1 KKK19533.1 - 2.7e-06 26.6 45.6 0.23 11.8 0.2 15.0 18 0 0 18 18 15 2 Leucine rich repeat RA PF00788.18 KKK19533.1 - 6e-06 26.6 0.0 3.8e-05 24.0 0.0 2.3 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain LRR_9 PF14580.1 KKK19533.1 - 0.00041 19.9 10.1 0.84 9.1 0.0 4.6 2 1 3 5 5 5 2 Leucine-rich repeat PP2C_2 PF13672.1 KKK19533.1 - 0.01 15.2 0.0 0.026 13.9 0.0 1.6 1 0 0 1 1 1 0 Protein phosphatase 2C LRR_5 PF13306.1 KKK19533.1 - 0.013 15.2 5.9 2.6 7.7 0.0 4.8 5 1 0 5 5 5 0 Leucine rich repeats (6 copies) Zn_clus PF00172.13 KKK19534.1 - 3.1e-07 30.2 9.3 4.5e-07 29.6 6.4 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SMC_Nse1 PF07574.8 KKK19534.1 - 0.044 13.3 0.1 0.061 12.9 0.0 1.2 1 0 0 1 1 1 0 Nse1 non-SMC component of SMC5-6 complex Dickkopf_N PF04706.7 KKK19534.1 - 8 6.7 12.0 27 5.0 8.2 1.8 1 1 1 2 2 2 0 Dickkopf N-terminal cysteine-rich region MSC PF09402.5 KKK19535.1 - 1.9e-97 326.0 0.0 2.7e-97 325.4 0.0 1.2 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain HeH PF12949.2 KKK19535.1 - 5.9e-17 60.9 0.1 1e-16 60.1 0.1 1.4 1 0 0 1 1 1 1 HeH/LEM domain DUF2630 PF10944.3 KKK19535.1 - 0.11 12.6 1.8 2.5 8.2 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2630) IMS PF00817.15 KKK19536.1 - 8.5e-42 142.4 0.0 1.5e-41 141.6 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 KKK19536.1 - 8.5e-19 67.7 0.0 2.1e-18 66.4 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain DUF4414 PF14377.1 KKK19536.1 - 4e-15 55.6 4.8 8.4e-07 28.8 0.1 3.4 3 0 0 3 3 3 2 Domain of unknown function (DUF4414) IMS_HHH PF11798.3 KKK19536.1 - 8.1e-07 28.7 0.1 4.5e-06 26.4 0.0 2.4 2 0 0 2 2 2 1 IMS family HHH motif PTCB-BRCT PF12738.2 KKK19536.1 - 0.00033 20.4 0.0 0.00089 19.0 0.0 1.8 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 KKK19536.1 - 0.00086 19.4 0.0 0.0028 17.7 0.0 1.9 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain Cdd1 PF11731.3 KKK19536.1 - 0.01 15.7 0.3 0.067 13.1 0.0 2.4 3 0 0 3 3 3 0 Pathogenicity locus HHH_5 PF14520.1 KKK19536.1 - 0.097 12.8 0.3 0.77 9.9 0.0 2.5 2 1 0 2 2 2 0 Helix-hairpin-helix domain Fungal_trans PF04082.13 KKK19537.1 - 5.4e-19 68.0 1.4 1.3e-17 63.5 0.0 2.5 3 0 0 3 3 3 2 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK19537.1 - 4.1e-08 33.0 7.9 4.1e-08 33.0 5.4 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HEAT PF02985.17 KKK19569.1 - 2.7e-27 92.3 17.0 7.9e-06 25.5 0.0 11.9 13 0 0 13 13 13 6 HEAT repeat HEAT_EZ PF13513.1 KKK19569.1 - 1.8e-26 91.8 13.2 8.1e-13 48.4 0.0 11.5 7 2 6 13 13 13 3 HEAT-like repeat HEAT_2 PF13646.1 KKK19569.1 - 7.1e-22 77.4 3.8 1.7e-07 31.3 0.0 8.5 3 3 5 8 8 8 5 HEAT repeats Cnd1 PF12717.2 KKK19569.1 - 5.3e-09 36.1 1.0 0.02 14.7 0.0 6.1 4 3 1 5 5 5 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.2 KKK19569.1 - 6.8e-08 32.8 0.0 0.15 12.4 0.0 6.3 4 3 4 8 8 8 1 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.15 KKK19569.1 - 1.6e-07 30.0 0.4 0.00023 19.6 0.0 3.6 3 0 0 3 3 3 2 Adaptin N terminal region CLASP_N PF12348.3 KKK19569.1 - 2.7e-06 26.8 0.4 27 4.0 0.0 6.7 5 2 2 7 7 7 0 CLASP N terminal Arm PF00514.18 KKK19569.1 - 2.2e-05 24.1 3.4 0.23 11.3 0.0 5.8 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat MMS19_C PF12460.3 KKK19569.1 - 9.7e-05 21.2 5.2 0.071 11.8 0.0 4.7 5 1 1 6 6 6 1 RNAPII transcription regulator C-terminal Xpo1 PF08389.7 KKK19569.1 - 0.00013 21.9 0.9 2.9 7.7 0.0 4.9 4 1 1 5 5 5 1 Exportin 1-like protein IBN_N PF03810.14 KKK19569.1 - 0.0014 18.5 2.0 0.2 11.5 0.0 4.7 4 1 1 5 5 5 1 Importin-beta N-terminal domain HEAT_PBS PF03130.11 KKK19569.1 - 0.0047 17.2 2.0 12 6.7 0.0 5.3 5 0 0 5 5 4 0 PBS lyase HEAT-like repeat Cohesin_HEAT PF12765.2 KKK19569.1 - 0.026 14.4 0.1 11 6.1 0.0 4.6 5 0 0 5 5 5 0 HEAT repeat associated with sister chromatid cohesion RIX1 PF08167.7 KKK19569.1 - 0.09 12.4 0.1 7.9 6.1 0.0 3.9 4 1 0 4 4 4 0 rRNA processing/ribosome biogenesis DUF3437 PF11919.3 KKK19569.1 - 0.12 12.1 0.0 0.48 10.1 0.0 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3437) DUF2741 PF10890.3 KKK19569.1 - 0.14 12.3 0.0 0.82 9.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2741) DUF1708 PF08101.6 KKK19569.1 - 0.15 10.8 0.0 0.24 10.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1708) Syja_N PF02383.13 KKK19570.1 - 4.5e-99 331.2 0.0 6.9e-99 330.6 0.0 1.3 1 0 0 1 1 1 1 SacI homology domain hSac2 PF12456.3 KKK19570.1 - 3.3e-38 129.5 0.0 6.7e-38 128.6 0.0 1.5 1 0 0 1 1 1 1 Inositol phosphatase Ribosomal_S3Ae PF01015.13 KKK19571.1 - 1.4e-43 148.4 0.3 1.7e-43 148.2 0.2 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family SCO1-SenC PF02630.9 KKK19571.1 - 0.09 12.3 0.0 0.23 11.0 0.0 1.6 1 1 0 2 2 2 0 SCO1/SenC E1-E2_ATPase PF00122.15 KKK19580.1 - 1.5e-59 200.8 0.3 3.6e-59 199.6 0.2 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KKK19580.1 - 4e-46 156.8 10.2 4e-46 156.8 7.1 2.2 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KKK19580.1 - 3.2e-27 96.3 0.0 8e-27 95.0 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KKK19580.1 - 7.4e-18 64.2 0.0 1.5e-17 63.3 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 KKK19580.1 - 3.3e-14 53.5 0.0 9e-14 52.0 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KKK19580.1 - 8.3e-08 31.5 0.8 8.5e-07 28.3 0.1 2.5 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 KKK19580.1 - 8.8e-05 22.1 0.0 0.0011 18.6 0.0 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Pyr_redox_3 PF13738.1 KKK19581.1 - 2.5e-10 40.7 0.0 0.0023 18.0 0.0 3.3 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KKK19581.1 - 9.7e-10 37.8 0.0 9.8e-05 21.4 0.0 3.0 4 0 0 4 4 4 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 KKK19581.1 - 2.1e-05 24.3 0.0 0.053 13.3 0.0 2.7 3 0 0 3 3 3 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 KKK19581.1 - 0.00018 21.4 0.0 0.46 10.3 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KKK19581.1 - 0.0014 17.6 0.9 0.32 9.8 0.0 2.5 2 1 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 KKK19581.1 - 0.0045 16.0 0.0 0.014 14.5 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 KKK19581.1 - 0.011 15.6 0.0 0.048 13.6 0.0 2.1 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 KKK19581.1 - 0.068 12.0 0.0 0.29 9.9 0.0 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A Lycopene_cycl PF05834.7 KKK19581.1 - 0.087 11.7 0.0 0.16 10.8 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein HI0933_like PF03486.9 KKK19581.1 - 0.21 10.0 0.0 0.78 8.1 0.0 1.8 2 0 0 2 2 2 0 HI0933-like protein HMG_CoA_synt_C PF08540.5 KKK19583.1 - 2.1e-104 348.9 0.7 3.1e-104 348.4 0.5 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.12 KKK19583.1 - 3e-94 313.4 0.1 5e-94 312.7 0.1 1.4 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal TFR_dimer PF04253.10 KKK19584.1 - 8.6e-35 119.0 0.1 1.5e-34 118.2 0.1 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.12 KKK19584.1 - 1.2e-13 51.2 0.0 2.4e-13 50.2 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 KKK19584.1 - 2e-06 27.4 0.0 3.6e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 PA domain DUF1765 PF08578.5 KKK19585.1 - 1.7e-44 150.9 6.1 3.5e-44 149.8 3.5 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1765) Glyco_hydro_75 PF07335.6 KKK19608.1 - 4.5e-42 143.5 0.0 6.7e-42 143.0 0.0 1.3 1 0 0 1 1 1 1 Fungal chitosanase of glycosyl hydrolase group 75 Nup96 PF12110.3 KKK19609.1 - 5.9e-100 334.1 0.2 1e-99 333.3 0.1 1.4 1 0 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.9 KKK19609.1 - 6.6e-45 152.3 0.0 1.3e-44 151.4 0.0 1.5 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.1 KKK19609.1 - 2.8e-15 56.5 183.5 5e-10 39.6 34.5 10.8 4 2 5 9 9 9 4 Nucleoporin FG repeat region Tet_res_leader PF08050.7 KKK19609.1 - 0.28 10.8 0.3 0.61 9.7 0.2 1.5 1 0 0 1 1 1 0 Tetracycline resistance leader peptide AMP-binding_C PF13193.1 KKK19610.1 - 8.5e-21 74.6 0.3 1.2e-20 74.2 0.2 1.2 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.23 KKK19610.1 - 0.00064 18.2 0.5 0.001 17.5 0.4 1.4 1 0 0 1 1 1 1 AMP-binding enzyme SAPS PF04499.10 KKK19611.1 - 1.3e-207 690.1 0.0 8.6e-206 684.1 0.0 2.9 3 0 0 3 3 3 1 SIT4 phosphatase-associated protein Apt1 PF10351.4 KKK19611.1 - 0.46 9.2 4.6 0.68 8.7 0.0 2.4 2 0 0 2 2 2 0 Golgi-body localisation protein domain MFS_1 PF07690.11 KKK19612.1 - 5.1e-50 170.1 28.2 2.3e-42 145.0 15.1 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KKK19612.1 - 5.2e-05 22.0 17.2 5.2e-05 22.0 11.9 3.5 3 1 0 3 3 3 3 Sugar (and other) transporter OATP PF03137.15 KKK19612.1 - 8.1 4.3 10.7 2.4 6.0 0.3 2.5 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Complex1_51K PF01512.12 KKK19613.1 - 1.3e-45 154.8 0.0 2.1e-45 154.1 0.0 1.4 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.4 KKK19613.1 - 3.7e-18 64.4 0.7 7.5e-18 63.4 0.5 1.5 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.4 KKK19613.1 - 9.3e-09 35.0 0.0 2.1e-08 33.9 0.0 1.7 1 0 0 1 1 1 1 SLBB domain SET PF00856.23 KKK19613.1 - 0.011 16.0 0.0 0.023 15.0 0.0 1.5 1 0 0 1 1 1 0 SET domain Fork_head PF00250.13 KKK19614.1 - 1.9e-38 130.3 2.0 3.9e-38 129.3 1.4 1.5 1 0 0 1 1 1 1 Fork head domain FHA PF00498.21 KKK19614.1 - 2.2e-08 34.0 0.0 5e-08 32.9 0.0 1.7 1 0 0 1 1 1 1 FHA domain TENA_THI-4 PF03070.11 KKK19615.1 - 9.9e-08 31.9 0.0 1.1e-06 28.5 0.0 2.4 2 1 1 3 3 3 1 TENA/THI-4/PQQC family Fructosamin_kin PF03881.9 KKK19615.1 - 0.0015 17.6 0.0 0.0023 16.9 0.0 1.2 1 0 0 1 1 1 1 Fructosamine kinase RNase_T PF00929.19 KKK19616.1 - 0.0019 18.5 0.0 0.0032 17.7 0.0 1.3 1 0 0 1 1 1 1 Exonuclease PHD PF00628.24 KKK19617.1 - 1.3e-08 34.3 10.0 2.5e-08 33.4 6.9 1.5 1 0 0 1 1 1 1 PHD-finger ING PF12998.2 KKK19617.1 - 6.2e-06 26.4 0.0 1.3e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding zf-RING-like PF08746.6 KKK19617.1 - 0.73 9.8 5.9 1.3 9.0 4.1 1.4 1 0 0 1 1 1 0 RING-like domain GFO_IDH_MocA PF01408.17 KKK19618.1 - 7.2e-09 36.1 0.3 3.5e-08 34.0 0.2 2.1 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold DHDPS PF00701.17 KKK19619.1 - 6e-33 113.6 0.0 4.5e-24 84.5 0.0 2.0 2 0 0 2 2 2 2 Dihydrodipicolinate synthetase family PEP_mutase PF13714.1 KKK19619.1 - 0.0048 16.1 0.0 0.0083 15.3 0.0 1.3 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase DIOX_N PF14226.1 KKK19619.1 - 0.11 13.0 0.1 0.25 11.8 0.0 1.6 2 0 0 2 2 2 0 non-haem dioxygenase in morphine synthesis N-terminal ADH_N PF08240.7 KKK19620.1 - 1.2e-25 89.4 3.9 2.3e-25 88.4 2.7 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KKK19620.1 - 9.7e-18 63.9 0.1 2.3e-17 62.7 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 KKK19620.1 - 0.00011 21.4 0.0 0.00018 20.7 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain WD40 PF00400.27 KKK19621.1 - 3.1e-44 147.3 8.0 2.2e-10 39.9 0.2 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat F-box-like PF12937.2 KKK19621.1 - 6.8e-12 44.9 0.2 1.4e-11 43.9 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KKK19621.1 - 1.4e-05 24.5 0.1 3.9e-05 23.1 0.0 1.8 1 0 0 1 1 1 1 F-box domain PQQ PF01011.16 KKK19621.1 - 0.012 15.1 0.1 17 5.1 0.0 3.4 3 0 0 3 3 3 0 PQQ enzyme repeat PQQ_2 PF13360.1 KKK19621.1 - 0.026 13.9 0.4 0.33 10.3 0.3 2.3 1 1 0 1 1 1 0 PQQ-like domain Elongin_A PF06881.6 KKK19621.1 - 0.078 13.3 0.0 0.15 12.4 0.0 1.5 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A zf-H2C2_2 PF13465.1 KKK19622.1 - 1.8e-05 24.7 3.3 1.8e-05 24.7 2.3 2.7 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2 PF00096.21 KKK19622.1 - 2.6e-05 24.2 19.3 2.8e-05 24.1 1.9 3.4 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 KKK19622.1 - 0.0013 18.8 0.7 0.0033 17.5 0.5 1.7 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 KKK19622.1 - 0.0015 18.7 0.7 0.0015 18.7 0.5 3.3 3 0 0 3 3 3 1 C2H2-type zinc finger zf-TRAF PF02176.13 KKK19622.1 - 0.17 12.2 6.2 0.24 11.7 1.5 2.3 2 0 0 2 2 2 0 TRAF-type zinc finger 2OG-FeII_Oxy PF03171.15 KKK19623.1 - 2.3e-05 24.6 0.0 5.6e-05 23.3 0.0 1.7 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Fungal_trans PF04082.13 KKK19624.1 - 0.00095 18.1 0.1 0.0014 17.5 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain CAP59_mtransfer PF11735.3 KKK19648.1 - 8e-82 274.1 0.0 1.1e-81 273.6 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 Gly_transf_sug PF04488.10 KKK19649.1 - 1.1e-07 32.1 0.0 1.3e-06 28.7 0.0 2.2 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif DUF3052 PF11253.3 KKK19649.1 - 0.077 12.5 0.0 0.2 11.2 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3052) TcdA_TcdB PF12919.2 KKK19649.1 - 0.081 11.3 0.0 0.12 10.8 0.0 1.1 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain CoxIIa PF08113.6 KKK19649.1 - 1.2 8.9 5.0 2.8 7.7 3.5 1.6 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IIa family Abhydrolase_6 PF12697.2 KKK19650.1 - 1.2e-10 41.6 0.8 2.4e-10 40.6 0.6 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KKK19650.1 - 2.7e-06 27.1 0.0 3.4e-06 26.8 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF2424 PF10340.4 KKK19650.1 - 0.007 15.0 0.0 0.009 14.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_1 PF00561.15 KKK19650.1 - 0.014 14.9 0.0 0.025 14.1 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold CALCOCO1 PF07888.6 KKK19650.1 - 0.21 9.8 0.0 0.36 9.0 0.0 1.3 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Abhydrolase_6 PF12697.2 KKK19651.1 - 3.1e-07 30.4 0.0 1.3e-06 28.4 0.0 2.2 2 1 0 2 2 2 1 Alpha/beta hydrolase family NACHT PF05729.7 KKK19651.1 - 1.9e-06 27.6 0.0 9.1e-05 22.1 0.0 2.8 1 1 0 1 1 1 1 NACHT domain Abhydrolase_5 PF12695.2 KKK19651.1 - 0.00031 20.5 0.0 0.0019 17.9 0.0 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family AAA_22 PF13401.1 KKK19651.1 - 0.00047 20.3 0.0 0.0026 17.9 0.0 2.2 1 1 0 1 1 1 1 AAA domain DUF676 PF05057.9 KKK19651.1 - 0.001 18.3 0.0 0.0025 17.1 0.0 1.6 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 KKK19651.1 - 0.0028 17.2 0.0 0.007 15.9 0.0 1.6 1 0 0 1 1 1 1 PGAP1-like protein RNA_helicase PF00910.17 KKK19651.1 - 0.0042 17.2 0.0 0.01 16.0 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_19 PF13245.1 KKK19651.1 - 0.024 14.3 0.0 0.37 10.5 0.0 2.8 3 0 0 3 3 3 0 Part of AAA domain Parvo_NS1 PF01057.12 KKK19651.1 - 0.025 13.4 0.0 0.085 11.7 0.0 1.7 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 Abhydrolase_2 PF02230.11 KKK19651.1 - 0.062 12.7 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase KAP_NTPase PF07693.9 KKK19651.1 - 0.13 11.1 0.0 0.23 10.4 0.0 1.3 1 0 0 1 1 1 0 KAP family P-loop domain DUF2075 PF09848.4 KKK19651.1 - 0.17 10.8 0.0 0.27 10.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ABC_tran PF00005.22 KKK19651.1 - 0.22 11.8 0.0 0.52 10.6 0.0 1.6 1 0 0 1 1 1 0 ABC transporter KaiC PF06745.8 KKK19651.1 - 0.24 10.4 0.0 4.2 6.4 0.0 2.3 2 0 0 2 2 2 0 KaiC AAA_16 PF13191.1 KKK19652.1 - 1.1e-06 28.8 0.3 3.7e-05 23.7 0.2 2.6 1 1 0 1 1 1 1 AAA ATPase domain Arch_ATPase PF01637.13 KKK19652.1 - 5.8e-06 26.1 0.0 9.7e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase AAA_22 PF13401.1 KKK19652.1 - 0.00061 19.9 0.0 0.0023 18.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 KKK19652.1 - 0.01 15.2 0.0 0.029 13.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.8 KKK19652.1 - 0.011 14.6 0.0 0.02 13.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) ATP-synt_ab PF00006.20 KKK19652.1 - 0.016 14.6 0.1 0.48 9.8 0.1 2.7 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA PF00004.24 KKK19652.1 - 0.021 15.0 0.0 0.062 13.4 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PEPCK_ATP PF01293.15 KKK19652.1 - 0.027 13.0 0.0 0.039 12.4 0.0 1.1 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase DUF377 PF04041.8 KKK19653.1 - 1.8e-44 151.7 0.0 2.4e-44 151.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF377) Glyco_hydro_43 PF04616.9 KKK19653.1 - 3.5e-08 32.8 2.6 0.00031 19.9 0.0 3.8 4 1 0 4 4 4 2 Glycosyl hydrolases family 43 Glyco_hydro_32N PF00251.15 KKK19653.1 - 2.1e-05 24.0 3.5 4.5e-05 22.9 0.0 2.4 3 0 0 3 3 3 1 Glycosyl hydrolases family 32 N-terminal domain MFS_1 PF07690.11 KKK19654.1 - 7.4e-44 149.8 46.1 3e-43 147.9 31.9 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KKK19654.1 - 1.5e-11 43.2 26.6 1.2e-09 36.9 18.5 2.8 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Candida_ALS_N PF11766.3 KKK19655.1 - 0.14 11.0 0.0 0.22 10.3 0.0 1.2 1 0 0 1 1 1 0 Cell-wall agglutinin N-terminal ligand-sugar binding Xan_ur_permease PF00860.15 KKK19656.1 - 3.5e-68 229.8 35.2 5.8e-68 229.1 24.4 1.3 1 0 0 1 1 1 1 Permease family CS PF04969.11 KKK19658.1 - 3.4e-09 37.1 0.0 5.6e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 CS domain Snf7 PF03357.16 KKK19659.1 - 4.5e-20 71.7 14.3 4.5e-20 71.7 9.9 1.8 1 1 1 2 2 2 1 Snf7 PSD4 PF07631.6 KKK19659.1 - 0.026 14.8 0.7 0.28 11.5 0.0 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF1592) MerR-DNA-bind PF09278.6 KKK19659.1 - 0.87 10.0 16.9 3.7 8.0 0.1 4.6 4 1 1 5 5 5 0 MerR, DNA binding DUF4404 PF14357.1 KKK19659.1 - 3.1 8.2 18.5 5.9 7.3 0.3 3.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4404) RRM_1 PF00076.17 KKK19660.1 - 2.7e-15 55.7 0.0 4.6e-15 54.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KKK19660.1 - 2.2e-12 46.7 0.0 3.7e-12 46.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KKK19660.1 - 1.9e-05 24.3 0.0 3.5e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.1 KKK19660.1 - 0.0001 22.7 1.5 0.0001 22.7 1.0 2.9 2 1 0 2 2 2 1 C-terminal duplication domain of Friend of PRMT1 HSP33 PF01430.14 KKK19660.1 - 0.053 12.6 0.0 0.082 12.0 0.0 1.2 1 0 0 1 1 1 0 Hsp33 protein WSC PF01822.14 KKK19662.1 - 3.8e-14 52.3 7.4 3.8e-14 52.3 5.1 2.3 2 1 0 2 2 2 1 WSC domain zf-CCCH PF00642.19 KKK19663.1 - 1.8e-05 24.2 0.9 1.8e-05 24.2 0.6 2.5 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Sugar_tr PF00083.19 KKK19664.1 - 4.5e-101 338.6 21.7 5.4e-101 338.3 15.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KKK19664.1 - 8.1e-19 67.5 36.4 1.6e-15 56.6 11.0 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily DAO PF01266.19 KKK19665.1 - 3.9e-19 68.7 0.0 6.4e-19 68.0 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Fcf1 PF04900.7 KKK19666.1 - 2.5e-37 127.0 2.2 4.8e-36 122.8 0.1 2.1 2 0 0 2 2 2 2 Fcf1 Y_phosphatase3 PF13350.1 KKK19669.1 - 2.1e-36 125.6 0.0 2.7e-36 125.2 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3C PF13348.1 KKK19669.1 - 1e-10 41.5 0.0 2.4e-10 40.3 0.0 1.7 1 0 0 1 1 1 1 Tyrosine phosphatase family C-terminal region Y_phosphatase2 PF03162.8 KKK19669.1 - 0.002 17.4 0.0 0.0032 16.8 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.22 KKK19669.1 - 0.014 14.7 0.0 0.021 14.1 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 KKK19669.1 - 0.059 13.4 0.0 0.099 12.6 0.0 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate Myotub-related PF06602.9 KKK19669.1 - 0.2 10.3 0.0 0.28 9.9 0.0 1.1 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain MFS_1 PF07690.11 KKK19670.1 - 2.7e-16 59.2 30.1 2.7e-16 59.2 20.9 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily PIG-L PF02585.12 KKK19671.1 - 2.1e-19 70.2 0.2 3.3e-19 69.6 0.1 1.3 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase PBP PF01161.15 KKK19672.1 - 1.4e-16 60.6 0.2 1.7e-16 60.4 0.2 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein zf-Paramyx-P PF13008.2 KKK19694.1 - 0.41 9.8 6.0 0.7 9.1 0.1 2.6 2 1 0 2 2 2 0 Zinc-binding domain of Paramyxoviridae V protein DnaJ_CXXCXGXG PF00684.14 KKK19694.1 - 0.65 10.0 9.6 1.6 8.7 1.8 2.6 1 1 2 3 3 3 0 DnaJ central domain UBA_4 PF14555.1 KKK19695.1 - 1.6e-11 43.4 0.1 3.3e-11 42.5 0.1 1.6 1 0 0 1 1 1 1 UBA-like domain UIM PF02809.15 KKK19695.1 - 1.1 8.9 6.3 0.13 11.8 1.1 2.1 2 0 0 2 2 2 0 Ubiquitin interaction motif Pkinase PF00069.20 KKK19696.1 - 1.4e-72 244.0 0.0 1.8e-72 243.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK19696.1 - 3.7e-36 124.5 0.0 5.1e-36 124.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase UBA_2 PF08587.6 KKK19696.1 - 4e-08 33.3 0.0 8.9e-08 32.2 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin associated domain (UBA) Kinase-like PF14531.1 KKK19696.1 - 4.1e-06 25.9 0.0 6.2e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 KKK19696.1 - 4.7e-05 22.8 0.1 8.7e-05 21.9 0.1 1.3 1 0 0 1 1 1 1 RIO1 family YukC PF10140.4 KKK19696.1 - 0.0068 15.0 0.1 0.011 14.4 0.1 1.1 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukC Kdo PF06293.9 KKK19696.1 - 0.029 13.4 0.2 0.13 11.2 0.1 2.1 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KKK19696.1 - 0.084 12.5 0.1 0.084 12.5 0.1 2.9 2 1 1 3 3 3 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 KKK19696.1 - 0.11 11.8 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL GSK-3_bind PF05350.7 KKK19696.1 - 0.21 11.0 7.8 0.43 9.9 5.4 1.5 1 0 0 1 1 1 0 Glycogen synthase kinase-3 binding ABC_tran PF00005.22 KKK19706.1 - 1.5e-35 122.4 0.0 1.8e-16 60.6 0.0 2.5 2 0 0 2 2 2 2 ABC transporter RLI PF04068.10 KKK19706.1 - 5.9e-14 51.3 5.0 5.9e-14 51.3 3.5 1.9 2 0 0 2 2 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI AAA_21 PF13304.1 KKK19706.1 - 8.9e-14 52.1 4.9 0.015 15.3 0.0 4.4 2 2 2 4 4 4 4 AAA domain SMC_N PF02463.14 KKK19706.1 - 2.9e-10 39.7 2.4 0.0013 18.0 0.1 4.1 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 KKK19706.1 - 3.5e-07 29.6 0.6 2.9 6.8 0.0 4.7 5 1 1 6 6 5 3 AAA ATPase domain AAA_17 PF13207.1 KKK19706.1 - 5.3e-06 27.2 0.8 0.14 12.9 0.0 3.6 3 2 0 3 3 2 2 AAA domain AAA PF00004.24 KKK19706.1 - 2.6e-05 24.4 0.0 0.027 14.6 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KKK19706.1 - 4.4e-05 23.6 0.0 0.016 15.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 KKK19706.1 - 7.4e-05 21.9 0.8 0.38 9.9 0.0 3.0 3 0 0 3 3 3 2 Protein of unknown function, DUF258 Fer4 PF00037.22 KKK19706.1 - 8.1e-05 22.0 2.5 8.1e-05 22.0 1.7 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_29 PF13555.1 KKK19706.1 - 0.00013 21.4 0.3 0.081 12.4 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_18 PF13238.1 KKK19706.1 - 0.00016 21.9 0.0 0.45 10.8 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 KKK19706.1 - 0.0011 18.8 0.0 0.088 12.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain Miro PF08477.8 KKK19706.1 - 0.0012 19.2 0.0 0.088 13.3 0.0 2.9 3 0 0 3 3 2 1 Miro-like protein VirE PF05272.6 KKK19706.1 - 0.0014 18.1 0.1 1.9 7.9 0.0 2.5 2 0 0 2 2 2 2 Virulence-associated protein E Fer4_21 PF14697.1 KKK19706.1 - 0.0022 17.7 11.1 0.0047 16.7 7.7 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain RNA_helicase PF00910.17 KKK19706.1 - 0.0029 17.7 0.4 1 9.5 0.0 2.8 3 0 0 3 3 2 1 RNA helicase MobB PF03205.9 KKK19706.1 - 0.0037 16.9 0.8 0.5 10.0 0.0 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.1 KKK19706.1 - 0.0037 16.6 0.1 2.2 7.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain UPF0079 PF02367.12 KKK19706.1 - 0.0038 16.8 0.2 0.059 12.9 0.0 2.5 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 Rad17 PF03215.10 KKK19706.1 - 0.005 15.5 0.0 0.073 11.7 0.0 2.1 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein SRP54 PF00448.17 KKK19706.1 - 0.0085 15.5 2.7 0.17 11.3 0.1 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Fer4_6 PF12837.2 KKK19706.1 - 0.01 15.6 2.1 0.01 15.6 1.5 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain AAA_23 PF13476.1 KKK19706.1 - 0.012 15.9 2.9 0.26 11.5 0.4 2.8 3 0 0 3 3 2 0 AAA domain NACHT PF05729.7 KKK19706.1 - 0.014 15.1 2.5 0.58 9.8 0.0 2.4 2 0 0 2 2 2 0 NACHT domain Fer4_10 PF13237.1 KKK19706.1 - 0.017 14.8 1.5 0.017 14.8 1.0 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain AAA_13 PF13166.1 KKK19706.1 - 0.038 12.4 0.0 0.038 12.4 0.0 1.7 2 0 0 2 2 1 0 AAA domain AAA_14 PF13173.1 KKK19706.1 - 0.048 13.5 0.0 3.9 7.4 0.0 2.8 2 1 0 2 2 2 0 AAA domain Fer4_16 PF13484.1 KKK19706.1 - 0.048 14.4 0.1 0.048 14.4 0.1 2.7 2 0 0 2 2 2 0 4Fe-4S double cluster binding domain AAA_28 PF13521.1 KKK19706.1 - 0.053 13.4 0.0 5.1 7.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.4 KKK19706.1 - 0.069 12.6 1.9 0.11 12.0 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NB-ARC PF00931.17 KKK19706.1 - 0.074 11.8 0.1 11 4.7 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain Thymidylate_kin PF02223.12 KKK19706.1 - 0.11 11.8 0.1 16 4.7 0.0 2.6 2 0 0 2 2 2 0 Thymidylate kinase KaiC PF06745.8 KKK19706.1 - 0.12 11.4 0.1 0.25 10.4 0.1 1.5 1 0 0 1 1 1 0 KaiC HflK_N PF12221.3 KKK19706.1 - 0.12 12.1 0.0 0.28 10.9 0.0 1.6 1 0 0 1 1 1 0 Bacterial membrane protein N terminal DLIC PF05783.6 KKK19706.1 - 0.13 10.8 0.0 0.22 10.1 0.0 1.2 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) Fer4_8 PF13183.1 KKK19706.1 - 0.19 11.7 8.7 0.81 9.7 6.2 1.9 1 1 0 1 1 1 0 4Fe-4S dicluster domain AAA_24 PF13479.1 KKK19706.1 - 0.22 11.0 2.1 1.1 8.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain Fer4_7 PF12838.2 KKK19706.1 - 0.39 11.1 13.2 0.048 14.0 1.4 2.4 1 1 2 3 3 3 0 4Fe-4S dicluster domain Fer4_2 PF12797.2 KKK19706.1 - 3.6 7.7 12.7 0.59 10.1 1.9 2.7 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_9 PF13187.1 KKK19706.1 - 9.3 6.6 18.1 0.053 13.7 1.3 2.6 2 1 1 3 3 2 0 4Fe-4S dicluster domain SNF2_N PF00176.18 KKK19707.1 - 1.4e-68 230.9 0.1 2.1e-68 230.3 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Chromo PF00385.19 KKK19707.1 - 1.7e-26 91.6 1.8 2.3e-15 56.0 0.3 3.0 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain DUF4208 PF13907.1 KKK19707.1 - 1.4e-14 54.1 0.1 4.6e-14 52.4 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4208) Helicase_C PF00271.26 KKK19707.1 - 1.1e-12 47.6 0.0 4.5e-12 45.6 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Hist_deacetyl PF00850.14 KKK19713.1 - 4.9e-60 203.4 0.0 6.9e-60 202.9 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain zf-AN1 PF01428.11 KKK19714.1 - 1.7e-23 82.1 18.5 3.2e-12 46.1 4.7 2.2 2 0 0 2 2 2 2 AN1-like Zinc finger Transp_Tc5_C PF04236.10 KKK19714.1 - 0.037 14.2 15.0 0.07 13.3 2.2 2.5 2 1 0 2 2 2 0 Tc5 transposase C-terminal domain zf-RING_5 PF14634.1 KKK19714.1 - 0.05 13.3 0.9 0.05 13.3 0.6 2.5 2 0 0 2 2 2 0 zinc-RING finger domain IBR PF01485.16 KKK19714.1 - 0.087 12.7 19.6 0.037 13.9 2.4 2.6 2 1 0 2 2 2 0 IBR domain C1_4 PF07975.7 KKK19714.1 - 0.36 10.8 14.4 0.84 9.6 2.5 3.0 2 1 0 2 2 2 0 TFIIH C1-like domain Ala_racemase_N PF01168.15 KKK19715.1 - 1.8e-41 142.0 0.2 2.2e-41 141.8 0.2 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain N_NLPC_P60 PF12912.2 KKK19716.1 - 0.0042 17.1 0.8 0.0054 16.8 0.6 1.2 1 0 0 1 1 1 1 NLPC_P60 stabilising domain, N term MFS_1 PF07690.11 KKK19717.1 - 7.1e-28 97.3 27.4 9.8e-28 96.8 19.0 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily DND1_DSRM PF14709.1 KKK19718.1 - 0.052 13.8 0.4 14 6.0 0.0 2.4 2 1 0 2 2 2 0 double strand RNA binding domain from DEAD END PROTEIN 1 DUF2583 PF10762.4 KKK19718.1 - 0.096 12.8 0.1 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2583) Thymidylat_synt PF00303.14 KKK19719.1 - 6.5e-96 320.4 0.0 7.6e-96 320.2 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase TGT PF01702.13 KKK19720.1 - 1.1e-93 312.8 0.0 1.4e-93 312.5 0.0 1.1 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase Adaptin_N PF01602.15 KKK19721.1 - 5.6e-85 285.6 4.6 6.7e-85 285.3 3.2 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.11 KKK19721.1 - 3.1e-44 149.5 0.0 7.6e-44 148.2 0.0 1.7 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.15 KKK19721.1 - 3.1e-19 69.3 0.0 7.3e-19 68.1 0.0 1.7 1 0 0 1 1 1 1 Adaptin C-terminal domain SbcD_C PF12320.3 KKK19721.1 - 0.088 12.8 1.1 0.62 10.1 0.1 2.6 2 0 0 2 2 2 0 Type 5 capsule protein repressor C-terminal domain Nop14 PF04147.7 KKK19722.1 - 5.2 4.8 10.8 6.8 4.4 7.5 1.1 1 0 0 1 1 1 0 Nop14-like family Peptidase_C15 PF01470.12 KKK19729.1 - 5.2e-13 49.3 0.0 0.00018 21.3 0.0 3.1 2 1 0 2 2 2 2 Pyroglutamyl peptidase MOSC_N PF03476.11 KKK19730.1 - 3.4e-20 71.9 0.0 2.2e-19 69.3 0.0 2.1 1 1 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.12 KKK19730.1 - 1.4e-17 63.4 0.5 3.1e-11 42.8 0.0 2.3 2 0 0 2 2 2 2 MOSC domain SR-25 PF10500.4 KKK19730.1 - 0.033 13.6 12.0 0.066 12.6 8.3 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Mad3_BUB1_I PF08311.7 KKK19732.1 - 3.1e-43 146.5 0.0 5.8e-43 145.6 0.0 1.5 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Pkinase PF00069.20 KKK19732.1 - 1.5e-12 47.2 0.0 5e-12 45.5 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Mad3_BUB1_II PF08171.6 KKK19732.1 - 0.00015 21.5 0.0 0.00055 19.7 0.0 2.0 1 0 0 1 1 1 1 Mad3/BUB1 homology region 2 Pkinase_Tyr PF07714.12 KKK19732.1 - 0.03 13.3 0.0 0.1 11.6 0.0 1.7 2 0 0 2 2 2 0 Protein tyrosine kinase Kinase-like PF14531.1 KKK19732.1 - 0.13 11.1 0.0 0.23 10.3 0.0 1.2 1 0 0 1 1 1 0 Kinase-like AP_endonuc_2 PF01261.19 KKK19733.1 - 1.8e-27 96.0 0.3 7.9e-27 93.9 0.0 1.9 2 0 0 2 2 2 1 Xylose isomerase-like TIM barrel TPT PF03151.11 KKK19734.1 - 2.8e-31 108.2 12.3 2.8e-31 108.2 8.5 2.5 2 1 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 KKK19734.1 - 8.4e-05 21.6 19.3 0.00013 20.9 13.4 1.3 1 0 0 1 1 1 1 UAA transporter family REV PF00424.13 KKK19734.1 - 0.0012 18.6 1.8 0.0023 17.7 1.3 1.4 1 0 0 1 1 1 1 REV protein (anti-repression trans-activator protein) EamA PF00892.15 KKK19734.1 - 1.3 9.1 40.3 0.15 12.1 8.7 3.3 3 2 0 3 3 3 0 EamA-like transporter family PBP1_TM PF14812.1 KKK19734.1 - 2.6 8.4 18.3 3.7 7.9 4.0 2.6 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal ADH_zinc_N PF00107.21 KKK19760.1 - 2.3e-10 40.0 0.0 4.1e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KKK19760.1 - 9.8e-08 31.7 0.0 6.9e-07 29.0 0.0 2.0 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 KKK19760.1 - 0.023 15.5 0.0 0.057 14.3 0.0 1.7 1 1 0 1 1 1 0 Zinc-binding dehydrogenase DUF1768 PF08719.6 KKK19761.1 - 6.5e-37 126.6 0.0 9.2e-37 126.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) Med1 PF10744.4 KKK19777.1 - 1.9e-112 375.8 0.0 2.5e-112 375.5 0.0 1.1 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription subunit 1 WD40 PF00400.27 KKK19778.1 - 7.1e-61 200.0 25.1 2.7e-12 46.0 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 KKK19778.1 - 0.0031 15.7 6.0 0.44 8.6 0.2 3.9 2 1 3 5 5 5 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 KKK19778.1 - 0.0075 14.6 0.1 0.76 8.0 0.0 2.2 2 0 0 2 2 2 2 Cytochrome D1 heme domain TPR_12 PF13424.1 KKK19779.1 - 1.1e-07 31.6 0.6 0.0019 18.1 0.0 4.0 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 KKK19779.1 - 1.1e-05 25.0 5.0 0.0012 18.5 0.1 4.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.23 KKK19779.1 - 0.00012 21.5 8.3 0.0011 18.4 0.1 3.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_10 PF13374.1 KKK19779.1 - 0.0014 18.5 0.4 0.013 15.4 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.1 KKK19779.1 - 0.0017 17.9 0.1 1.2 8.8 0.0 3.6 3 0 0 3 3 3 1 TPR repeat TPR_14 PF13428.1 KKK19779.1 - 0.075 13.7 2.4 13 6.7 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.1 KKK19779.1 - 0.19 11.6 2.3 2.5 8.1 0.0 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.1 KKK19779.1 - 1.5 8.7 3.8 12 5.9 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF159 PF02586.9 KKK19780.1 - 5.9e-57 192.5 0.0 8.9e-57 191.9 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, COG2135 Sdh5 PF03937.11 KKK19782.1 - 1.5e-23 82.2 1.5 1.9e-23 81.9 0.4 1.6 2 0 0 2 2 2 1 Flavinator of succinate dehydrogenase Pkinase PF00069.20 KKK19793.1 - 4.1e-27 94.9 0.0 5.7e-27 94.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK19793.1 - 1.9e-09 36.9 0.0 0.00056 19.0 0.0 2.0 2 0 0 2 2 2 2 Protein tyrosine kinase SRF-TF PF00319.13 KKK19794.1 - 4.4e-23 80.2 0.1 6.7e-23 79.6 0.1 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) CIAPIN1 PF05093.8 KKK19795.1 - 1.3e-34 118.2 2.1 2e-34 117.6 1.4 1.3 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis Dicty_REP PF05086.7 KKK19796.1 - 2.6 5.6 13.5 3.9 5.1 9.3 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein TFIIA PF03153.8 KKK19796.1 - 3.5 7.4 8.2 5.2 6.8 5.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Med3 PF11593.3 KKK19796.1 - 6.6 5.8 30.8 10 5.2 21.4 1.4 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Peptidase_M28 PF04389.12 KKK19797.1 - 2.9e-34 118.3 0.1 5.3e-34 117.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 KKK19797.1 - 3.3e-13 49.1 0.3 7.9e-13 47.9 0.2 1.7 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.23 KKK19797.1 - 0.00029 20.3 4.3 0.00035 20.1 0.0 2.8 2 2 0 3 3 3 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.9 KKK19797.1 - 0.055 12.2 0.0 0.32 9.7 0.0 2.1 2 0 0 2 2 2 0 M42 glutamyl aminopeptidase Nicastrin PF05450.10 KKK19797.1 - 0.07 12.3 0.0 0.15 11.2 0.0 1.4 1 0 0 1 1 1 0 Nicastrin Exo_endo_phos PF03372.18 KKK19798.1 - 3.7e-05 23.7 0.0 0.0049 16.8 0.0 2.2 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LysM PF01476.15 KKK19799.1 - 2.6e-24 84.8 0.0 3.2e-06 26.9 0.0 4.2 4 0 0 4 4 4 4 LysM domain GMC_oxred_C PF05199.8 KKK19800.1 - 1.1e-33 116.5 1.4 1.4e-32 112.9 0.3 2.2 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_N PF00732.14 KKK19800.1 - 1e-30 106.9 0.0 3e-27 95.5 0.0 3.0 1 1 0 2 2 2 2 GMC oxidoreductase FAD_binding_2 PF00890.19 KKK19800.1 - 0.00099 18.0 0.2 0.0087 14.9 0.4 2.0 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 KKK19800.1 - 0.0037 17.1 0.0 0.04 13.8 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KKK19800.1 - 0.0041 17.1 0.2 0.013 15.5 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KKK19800.1 - 0.015 14.2 0.3 0.3 9.9 0.1 2.7 3 0 0 3 3 3 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KKK19800.1 - 0.022 14.8 0.0 1.2 9.1 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 KKK19800.1 - 0.081 12.3 0.4 0.16 11.4 0.3 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA HI0933_like PF03486.9 KKK19800.1 - 0.19 10.1 0.2 2.1 6.7 0.0 2.0 2 0 0 2 2 2 0 HI0933-like protein Cas_CXXC_CXXC PF09706.5 KKK19801.1 - 0.074 13.2 4.0 11 6.2 0.1 4.0 4 0 0 4 4 4 0 CRISPR-associated protein (Cas_CXXC_CXXC) zf-RING_4 PF14570.1 KKK19801.1 - 1.5 8.4 11.6 15 5.2 0.0 4.8 5 0 0 5 5 5 0 RING/Ubox like zinc-binding domain F-box-like PF12937.2 KKK19802.1 - 0.0078 15.9 0.1 0.016 14.8 0.0 1.5 1 0 0 1 1 1 1 F-box-like Fungal_trans PF04082.13 KKK19803.1 - 6.3e-14 51.4 1.2 1.8e-13 50.0 0.8 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK19803.1 - 7.3e-07 28.9 14.7 1.4e-06 28.1 10.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cu_amine_oxid PF01179.15 KKK19804.1 - 7.6e-165 548.6 0.0 9.8e-165 548.2 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.11 KKK19804.1 - 4.3e-05 23.4 0.0 9.1e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.11 KKK19804.1 - 0.00038 20.4 0.1 0.00075 19.5 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain CorA PF01544.13 KKK19805.1 - 9.6e-05 21.5 0.6 0.00028 20.0 0.0 2.0 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein 2OG-FeII_Oxy PF03171.15 KKK19806.1 - 1.7e-12 47.4 0.0 2.9e-12 46.7 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Ribonuc_L-PSP PF01042.16 KKK19807.1 - 2.2e-17 62.9 0.0 3.5e-17 62.2 0.0 1.3 1 1 0 1 1 1 1 Endoribonuclease L-PSP RVT_1 PF00078.22 KKK19809.1 - 3.1e-05 23.4 0.0 6.2e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) U5_2-snRNA_bdg PF10597.4 KKK19809.1 - 0.012 15.1 0.0 0.03 13.9 0.0 1.6 1 0 0 1 1 1 0 U5-snRNA binding site 2 of PrP8 Nucleoplasmin PF03066.10 KKK19809.1 - 0.065 12.7 1.9 0.13 11.7 1.3 1.5 1 0 0 1 1 1 0 Nucleoplasmin DUF2457 PF10446.4 KKK19809.1 - 0.086 11.5 5.7 0.14 10.8 4.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) NOA36 PF06524.7 KKK19809.1 - 1.7 7.8 4.4 2.7 7.1 3.1 1.2 1 0 0 1 1 1 0 NOA36 protein DUF4611 PF15387.1 KKK19809.1 - 4.5 7.4 7.3 16 5.7 5.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) 3-HAO PF06052.7 KKK19810.1 - 2.9e-55 185.8 0.1 3.6e-55 185.5 0.1 1.1 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.6 KKK19810.1 - 0.0022 17.4 0.0 0.0038 16.6 0.0 1.4 1 0 0 1 1 1 1 Cupin domain T2SI PF02501.12 KKK19810.1 - 0.15 12.0 0.7 8.4 6.4 0.1 2.4 3 0 0 3 3 3 0 Type II secretion system (T2SS), protein I Amidohydro_2 PF04909.9 KKK19811.1 - 1.3e-41 143.0 0.2 1.5e-41 142.8 0.1 1.0 1 0 0 1 1 1 1 Amidohydrolase Aldedh PF00171.17 KKK19812.1 - 1.6e-146 488.2 0.0 1.8e-146 488.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Adaptin_N PF01602.15 KKK19813.1 - 1.6e-140 468.9 3.0 1.9e-140 468.6 2.1 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.15 KKK19813.1 - 2.2e-19 69.8 0.0 4e-19 69.0 0.0 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain HEAT_2 PF13646.1 KKK19813.1 - 5.5e-07 29.7 1.6 0.07 13.4 0.0 4.0 3 1 2 5 5 5 3 HEAT repeats Cnd1 PF12717.2 KKK19813.1 - 0.00098 19.0 2.0 0.014 15.2 0.5 3.2 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.1 KKK19813.1 - 0.0023 18.3 0.7 6.9 7.2 0.1 4.9 4 1 0 4 4 4 1 HEAT-like repeat HEAT PF02985.17 KKK19813.1 - 0.0042 17.0 2.1 13 6.1 0.0 4.8 4 1 0 4 4 4 1 HEAT repeat TIP120 PF08623.5 KKK19813.1 - 0.0063 16.1 0.6 0.033 13.7 0.0 2.3 2 0 0 2 2 2 1 TATA-binding protein interacting (TIP20) Arm PF00514.18 KKK19813.1 - 0.031 14.1 0.2 31 4.5 0.1 4.4 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat DnaJ PF00226.26 KKK19814.1 - 1.8e-23 82.0 1.0 4.2e-23 80.8 0.7 1.7 1 0 0 1 1 1 1 DnaJ domain Endonuc_Holl PF10107.4 KKK19814.1 - 5.9 6.5 9.0 0.46 10.1 0.1 2.5 2 0 0 2 2 2 0 Endonuclease related to archaeal Holliday junction resolvase Pkinase PF00069.20 KKK19815.1 - 1.9e-09 37.1 0.0 4.8e-09 35.7 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK19815.1 - 4.1e-08 32.6 0.0 7.8e-08 31.7 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KKK19815.1 - 0.03 13.3 0.0 0.055 12.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family F-box-like PF12937.2 KKK19816.1 - 1.6e-13 50.1 0.6 1.6e-13 50.1 0.4 2.4 3 0 0 3 3 3 1 F-box-like LRR_8 PF13855.1 KKK19816.1 - 8.8e-12 44.6 12.9 0.11 12.3 1.0 6.8 3 1 3 6 6 6 6 Leucine rich repeat LRR_4 PF12799.2 KKK19816.1 - 2.3e-11 43.0 4.6 0.29 10.7 0.0 7.4 5 3 1 7 7 7 5 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 KKK19816.1 - 1.2e-10 40.2 6.7 3.4 8.0 0.1 10.7 12 0 0 12 12 12 1 Leucine Rich repeat F-box PF00646.28 KKK19816.1 - 4e-05 23.1 0.2 4e-05 23.1 0.1 2.5 3 0 0 3 3 3 1 F-box domain LRR_1 PF00560.28 KKK19816.1 - 0.01 15.7 24.4 39 4.8 0.0 10.1 8 4 0 8 8 8 0 Leucine Rich Repeat DUF1699 PF08004.6 KKK19816.1 - 0.047 13.2 2.0 0.45 10.0 0.0 3.3 3 1 1 4 4 4 0 Protein of unknown function (DUF1699) AMP-binding PF00501.23 KKK19817.1 - 6.1e-70 235.7 0.0 8.4e-70 235.2 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KKK19817.1 - 1.1e-16 61.4 0.1 2.4e-16 60.4 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain MBOAT PF03062.14 KKK19818.1 - 8e-36 123.7 22.1 8e-36 123.7 15.3 2.1 2 1 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family Zn_clus PF00172.13 KKK19819.1 - 5.2 7.0 12.2 0.67 9.9 5.3 1.9 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain TauD PF02668.11 KKK19820.1 - 2e-13 50.6 0.5 2.2e-07 30.7 0.2 2.2 1 1 1 2 2 2 2 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.5 KKK19820.1 - 0.094 11.5 0.3 0.17 10.7 0.2 1.3 1 0 0 1 1 1 0 CsiD Peptidase_M28 PF04389.12 KKK19822.1 - 2e-32 112.3 0.0 3.8e-32 111.4 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 ATP-synt_8 PF00895.15 KKK19822.1 - 0.0049 17.0 0.8 0.0049 17.0 0.5 5.0 7 0 0 7 7 7 1 ATP synthase protein 8 Peptidase_M20 PF01546.23 KKK19822.1 - 0.032 13.7 0.0 0.053 13.0 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 Pox_Ag35 PF03286.9 KKK19822.1 - 0.35 10.3 1.1 0.6 9.6 0.7 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Ribosomal_60s PF00428.14 KKK19822.1 - 0.38 11.1 6.0 1 9.8 4.1 1.7 1 0 0 1 1 1 0 60s Acidic ribosomal protein DUF2457 PF10446.4 KKK19822.1 - 1.4 7.6 9.0 2.3 6.8 6.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CENP-B_dimeris PF09026.5 KKK19822.1 - 2.5 8.3 10.1 6 7.1 7.0 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Nucleoplasmin PF03066.10 KKK19822.1 - 3.7 7.0 10.7 6.4 6.2 6.9 1.7 2 0 0 2 2 2 0 Nucleoplasmin Daxx PF03344.10 KKK19822.1 - 5.4 5.3 5.9 7.6 4.8 4.1 1.1 1 0 0 1 1 1 0 Daxx Family NOA36 PF06524.7 KKK19822.1 - 9.5 5.3 5.0 15 4.7 3.4 1.2 1 0 0 1 1 1 0 NOA36 protein Ribosomal_L13 PF00572.13 KKK19823.1 - 1.4e-27 96.2 0.0 2.7e-27 95.3 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L13 Aminotran_1_2 PF00155.16 KKK19824.1 - 1.2e-61 208.6 0.0 1.5e-61 208.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 KKK19824.1 - 2.3e-05 23.7 0.0 4.1e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 KKK19824.1 - 0.027 13.1 0.0 0.04 12.6 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V LisH PF08513.6 KKK19836.1 - 2.5e-05 23.8 0.2 4.9e-05 22.9 0.1 1.5 1 0 0 1 1 1 1 LisH TRAPP PF04051.11 KKK19837.1 - 7.2e-39 132.7 0.0 9e-39 132.4 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component DUF4250 PF14056.1 KKK19837.1 - 0.13 11.9 1.1 0.16 11.6 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4250) WD40 PF00400.27 KKK19839.1 - 6.3e-61 200.2 6.2 6e-09 35.4 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 KKK19839.1 - 1.6e-05 24.7 0.0 0.29 10.8 0.0 3.1 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 KKK19839.1 - 2e-05 23.5 3.8 0.029 13.1 0.3 3.7 1 1 2 3 3 3 2 Nup133 N terminal like PQQ_2 PF13360.1 KKK19839.1 - 0.0064 15.9 0.3 7 6.0 0.0 3.2 2 1 1 3 3 3 1 PQQ-like domain Pribosyltran PF00156.22 KKK19840.1 - 8.2e-16 57.8 0.0 1.1e-15 57.4 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 KKK19840.1 - 0.0037 16.4 0.0 0.0053 15.9 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase AIG2_2 PF13772.1 KKK19841.1 - 4.7e-05 23.4 0.0 0.0064 16.5 0.0 2.3 2 0 0 2 2 2 2 AIG2-like family TGF_beta_GS PF08515.7 KKK19841.1 - 0.24 10.7 1.3 0.4 10.0 0.9 1.4 1 0 0 1 1 1 0 Transforming growth factor beta type I GS-motif Glyco_hydro_47 PF01532.15 KKK19842.1 - 9.6e-135 449.7 0.0 1.2e-134 449.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 EcoRII-C PF09019.6 KKK19842.1 - 0.29 10.9 0.0 0.51 10.1 0.0 1.3 1 0 0 1 1 1 0 EcoRII C terminal Ribonuc_L-PSP PF01042.16 KKK19843.1 - 7e-39 132.3 0.0 7.6e-39 132.2 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP GTP_EFTU PF00009.22 KKK19845.1 - 3.2e-60 202.7 0.1 6.4e-60 201.8 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 KKK19845.1 - 2.7e-37 126.9 0.0 6.8e-37 125.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 KKK19845.1 - 6.2e-21 74.0 0.0 1.9e-20 72.5 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 KKK19845.1 - 2.2e-13 50.1 0.1 9.4e-13 48.0 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_II PF14492.1 KKK19845.1 - 1.5e-11 43.9 0.0 5.9e-11 42.0 0.0 2.0 1 0 0 1 1 1 1 Elongation Factor G, domain II RRM_6 PF14259.1 KKK19845.1 - 1.3e-10 41.0 0.1 8.2e-09 35.3 0.0 3.6 3 0 0 3 3 3 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) PWI PF01480.12 KKK19845.1 - 1e-09 38.3 0.1 2.3e-09 37.2 0.1 1.7 1 0 0 1 1 1 1 PWI domain RRM_5 PF13893.1 KKK19845.1 - 8.3e-09 35.1 0.0 2e-08 33.9 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KKK19845.1 - 5.2e-07 29.2 0.7 0.0001 21.8 0.0 3.9 4 0 0 4 4 4 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MMR_HSR1 PF01926.18 KKK19845.1 - 5.5e-06 26.3 0.0 1.5e-05 24.9 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase Nup35_RRM_2 PF14605.1 KKK19845.1 - 2.9e-05 23.7 0.0 0.0017 18.0 0.0 2.6 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif zf-CCCH PF00642.19 KKK19845.1 - 0.0025 17.4 1.0 0.0043 16.6 0.7 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_3 PF08777.6 KKK19845.1 - 0.44 10.4 0.0 0.44 10.4 0.0 2.9 2 0 0 2 2 1 0 RNA binding motif Borrelia_P83 PF05262.6 KKK19845.1 - 0.48 8.6 8.7 0.82 7.8 6.1 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein VIT1 PF01988.14 KKK19845.1 - 0.6 9.5 4.3 1.2 8.5 3.0 1.4 1 0 0 1 1 1 0 VIT family DUF663 PF04950.7 KKK19846.1 - 8.1e-94 313.9 0.0 8.1e-94 313.9 0.0 1.8 2 0 0 2 2 1 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 KKK19846.1 - 2.1e-25 88.0 0.0 4.5e-25 86.9 0.0 1.6 1 0 0 1 1 1 1 AARP2CN (NUC121) domain GTP_EFTU PF00009.22 KKK19846.1 - 9.7e-07 28.4 0.0 0.00017 21.0 0.0 2.5 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 KKK19846.1 - 1.3e-05 25.3 0.0 3.6e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KKK19846.1 - 8.8e-05 22.5 0.0 0.0002 21.3 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.1 KKK19846.1 - 0.00042 20.2 0.0 0.0013 18.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 KKK19846.1 - 0.00053 20.1 0.0 0.0012 19.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MobB PF03205.9 KKK19846.1 - 0.00059 19.5 0.3 0.0015 18.2 0.2 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 KKK19846.1 - 0.0014 18.5 0.0 0.0038 17.1 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_17 PF13207.1 KKK19846.1 - 0.0025 18.6 0.0 0.0025 18.6 0.0 4.6 3 1 1 4 4 3 1 AAA domain Miro PF08477.8 KKK19846.1 - 0.0029 18.0 0.0 0.0088 16.5 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein AAA_19 PF13245.1 KKK19846.1 - 0.0031 17.2 0.2 0.0077 15.9 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain NACHT PF05729.7 KKK19846.1 - 0.0039 16.8 0.0 0.0078 15.8 0.0 1.5 1 0 0 1 1 1 1 NACHT domain ABC_tran PF00005.22 KKK19846.1 - 0.0045 17.2 1.1 0.014 15.6 0.0 2.4 3 0 0 3 3 1 1 ABC transporter AAA_25 PF13481.1 KKK19846.1 - 0.0077 15.6 0.0 0.025 13.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.10 KKK19846.1 - 0.011 15.4 0.3 0.021 14.5 0.2 1.4 1 0 0 1 1 1 0 NTPase NB-ARC PF00931.17 KKK19846.1 - 0.013 14.4 0.0 0.024 13.4 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_24 PF13479.1 KKK19846.1 - 0.013 15.1 0.1 0.031 13.8 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 KKK19846.1 - 0.013 15.3 0.0 0.035 13.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 KKK19846.1 - 0.013 15.1 0.2 0.11 12.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) cobW PF02492.14 KKK19846.1 - 0.014 14.8 0.2 0.026 13.9 0.2 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.17 KKK19846.1 - 0.016 15.3 0.0 0.038 14.1 0.0 1.6 1 0 0 1 1 1 0 RNA helicase PduV-EutP PF10662.4 KKK19846.1 - 0.017 14.6 0.0 0.14 11.6 0.0 2.1 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation DUF258 PF03193.11 KKK19846.1 - 0.028 13.5 0.0 0.056 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Septin PF00735.13 KKK19846.1 - 0.065 12.2 1.1 0.29 10.1 0.0 2.2 2 0 0 2 2 2 0 Septin ATP_bind_1 PF03029.12 KKK19846.1 - 0.18 11.3 0.0 0.32 10.5 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Viral_helicase1 PF01443.13 KKK19846.1 - 0.2 11.1 0.0 0.38 10.2 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase BCDHK_Adom3 PF10436.4 KKK19847.1 - 4.9e-31 107.4 0.0 6.8e-28 97.2 0.0 2.2 1 1 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 KKK19847.1 - 5.9e-18 64.6 0.0 1.9e-17 62.9 0.0 1.8 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Inhibitor_I9 PF05922.11 KKK19847.1 - 0.00044 20.7 0.3 0.0015 19.0 0.0 2.0 2 0 0 2 2 2 1 Peptidase inhibitor I9 HATPase_c_2 PF13581.1 KKK19847.1 - 0.032 13.9 0.1 0.22 11.3 0.0 2.1 1 1 0 1 1 1 0 Histidine kinase-like ATPase domain HATPase_c_3 PF13589.1 KKK19847.1 - 0.032 13.8 0.0 0.17 11.5 0.0 2.0 1 1 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Aminotran_1_2 PF00155.16 KKK19848.1 - 8.3e-24 84.1 0.0 1e-23 83.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 KKK19848.1 - 0.00085 17.9 0.0 0.0012 17.5 0.0 1.2 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase Beta_elim_lyase PF01212.16 KKK19848.1 - 0.0039 16.3 0.0 0.0056 15.8 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 KKK19848.1 - 0.067 12.2 0.0 1.1 8.2 0.0 2.1 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family Glyoxalase_2 PF12681.2 KKK19849.1 - 3.1e-13 50.2 0.0 1e-12 48.5 0.0 1.9 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 KKK19849.1 - 1.7e-10 40.9 0.0 9.2e-10 38.5 0.0 2.1 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 KKK19849.1 - 0.00041 20.3 0.0 0.00079 19.4 0.0 1.6 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily UQ_con PF00179.21 KKK19924.1 - 6.8e-50 168.1 0.0 8.4e-50 167.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KKK19924.1 - 6e-05 22.8 0.1 0.00011 21.9 0.0 1.5 2 0 0 2 2 2 1 Prokaryotic E2 family B RWD PF05773.17 KKK19924.1 - 0.0004 20.2 0.1 0.0006 19.6 0.1 1.6 1 1 0 1 1 1 1 RWD domain UEV PF05743.8 KKK19924.1 - 0.0018 17.9 0.0 0.0026 17.4 0.0 1.4 1 0 0 1 1 1 1 UEV domain F-box-like PF12937.2 KKK19925.1 - 2.2e-08 33.7 0.1 4.1e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KKK19925.1 - 1e-06 28.2 0.0 2.4e-06 27.0 0.0 1.7 1 0 0 1 1 1 1 F-box domain Nucleos_tra2_C PF07662.8 KKK19926.1 - 2e-69 233.2 0.4 2e-69 233.2 0.2 2.5 2 1 0 2 2 2 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.15 KKK19926.1 - 3.9e-23 81.5 4.7 3.9e-23 81.5 3.3 2.6 2 0 0 2 2 2 1 Na+ dependent nucleoside transporter N-terminus Gate PF07670.9 KKK19926.1 - 7.1 6.5 27.8 0.017 15.0 6.3 3.9 4 1 0 4 4 4 0 Nucleoside recognition Pkinase PF00069.20 KKK19927.1 - 2.2e-58 197.4 0.0 3e-58 197.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK19927.1 - 1e-24 87.0 0.0 1.5e-24 86.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KKK19927.1 - 1.5e-07 30.6 0.0 2.2e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KKK19927.1 - 0.012 14.6 0.0 0.035 13.1 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KKK19927.1 - 0.027 14.1 0.0 0.23 11.1 0.0 2.3 2 0 0 2 2 2 0 Phosphotransferase enzyme family ATG2_CAD PF13329.1 KKK19928.1 - 4.3e-49 166.1 0.3 1.3e-48 164.5 0.0 2.1 2 0 0 2 2 2 1 Autophagy-related protein 2 CAD motif ATG_C PF09333.6 KKK19928.1 - 1.1e-28 99.2 0.1 9e-28 96.3 0.0 2.4 2 0 0 2 2 2 1 ATG C terminal domain A_deaminase PF00962.17 KKK19929.1 - 3.1e-13 49.3 0.0 4.8e-06 25.7 0.0 2.2 2 0 0 2 2 2 2 Adenosine/AMP deaminase PolyA_pol_arg_C PF12626.2 KKK19929.1 - 0.07 12.7 0.4 0.16 11.6 0.2 1.5 1 0 0 1 1 1 0 Polymerase A arginine-rich C-terminus Ribosomal_L31e PF01198.14 KKK19930.1 - 4.3e-39 132.0 1.5 5.7e-39 131.6 1.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L31e CN_hydrolase PF00795.17 KKK19931.1 - 2.2e-32 111.9 0.0 3e-32 111.5 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase TFIIA PF03153.8 KKK19932.1 - 2 8.2 9.7 3.4 7.4 6.7 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ish1 PF10281.4 KKK19935.1 - 5.3e-83 272.6 9.5 9.6e-12 44.7 0.0 7.4 7 0 0 7 7 7 7 Putative stress-responsive nuclear envelope protein SAP PF02037.22 KKK19935.1 - 1.9e-10 39.9 0.0 0.63 9.6 0.0 6.4 5 2 0 5 5 5 3 SAP domain HeH PF12949.2 KKK19935.1 - 2.3e-10 39.8 0.0 0.15 11.6 0.1 5.9 6 0 0 6 6 6 3 HeH/LEM domain Slx4 PF09494.5 KKK19935.1 - 5.9e-06 25.9 0.8 9.8 6.0 0.0 5.6 5 0 0 5 5 5 1 Slx4 endonuclease APC2 PF08672.6 KKK19935.1 - 3.3e-05 24.0 4.6 7 6.9 0.0 6.6 7 0 0 7 7 7 1 Anaphase promoting complex (APC) subunit 2 LEM PF03020.10 KKK19935.1 - 0.022 14.2 0.0 35 3.9 0.0 4.5 6 0 0 6 6 6 0 LEM domain Amidase02_C PF12123.3 KKK19935.1 - 0.025 14.2 0.1 6 6.6 0.2 3.7 3 0 0 3 3 3 0 N-acetylmuramoyl-l-alanine amidase SAM_2 PF07647.12 KKK19935.1 - 0.16 11.8 8.9 13 5.7 0.0 5.8 6 1 1 7 7 7 0 SAM domain (Sterile alpha motif) Apolipoprotein PF01442.13 KKK19935.1 - 0.3 10.5 4.8 1.3 8.4 1.4 2.7 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain DUF1470 PF07336.6 KKK19935.1 - 1.5 9.1 28.0 1.9 8.8 1.6 5.6 5 1 0 5 5 5 0 Protein of unknown function (DUF1470) PQ-loop PF04193.9 KKK19936.1 - 1.8e-20 72.2 15.1 7.1e-12 44.7 3.6 3.6 3 1 1 4 4 4 2 PQ loop repeat CTV_P6 PF06706.6 KKK19936.1 - 0.15 11.5 2.9 0.74 9.3 0.3 2.6 2 0 0 2 2 2 0 Citrus tristeza virus 6-kDa protein NTF2 PF02136.15 KKK19938.1 - 4.5e-32 110.9 0.0 4.9e-32 110.7 0.0 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Surp PF01805.15 KKK19939.1 - 3.5e-17 61.7 0.0 6.8e-17 60.8 0.0 1.5 1 0 0 1 1 1 1 Surp module POTRA_2 PF08479.6 KKK19939.1 - 0.05 13.2 0.1 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 POTRA domain, ShlB-type Glycos_transf_2 PF00535.21 KKK19940.1 - 3.4e-34 117.9 0.0 4.2e-34 117.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 KKK19940.1 - 8.1e-15 55.2 0.0 1.2e-14 54.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 KKK19940.1 - 1.4e-07 30.8 0.0 2.1e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 KKK19940.1 - 0.0002 20.6 0.0 0.00034 19.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_trans_2_3 PF13632.1 KKK19940.1 - 0.0079 15.9 0.0 0.011 15.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_4 PF13704.1 KKK19940.1 - 0.077 13.3 0.0 0.15 12.3 0.0 1.5 1 1 0 1 1 1 0 Glycosyl transferase family 2 DUF3169 PF11368.3 KKK19941.1 - 0.37 9.9 0.1 0.56 9.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) Vps35 PF03635.12 KKK19942.1 - 0 1042.8 0.5 0 1042.6 0.3 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 TerB-C PF15615.1 KKK19942.1 - 0.016 15.4 3.5 0.29 11.3 1.8 2.6 2 0 0 2 2 2 0 TerB-C domain DUF3907 PF13047.1 KKK19942.1 - 0.032 13.8 0.0 5.4 6.6 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3907) WD40 PF00400.27 KKK19944.1 - 0.11 12.4 10.6 8.2 6.4 1.6 4.8 5 0 0 5 5 5 0 WD domain, G-beta repeat Daxx PF03344.10 KKK19944.1 - 1.2 7.4 15.6 2 6.8 10.8 1.2 1 0 0 1 1 1 0 Daxx Family Nop14 PF04147.7 KKK19944.1 - 4 5.2 16.0 6.2 4.6 11.1 1.2 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.7 KKK19944.1 - 9.3 5.4 14.0 20 4.3 9.7 1.5 1 0 0 1 1 1 0 SDA1 DUF1749 PF08538.5 KKK19945.1 - 7.1e-108 360.0 0.0 8.2e-108 359.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.2 KKK19945.1 - 6.7e-07 29.4 0.5 2.5e-06 27.5 0.3 1.8 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KKK19945.1 - 0.00013 21.7 0.0 0.00081 19.1 0.0 1.9 1 1 1 2 2 2 1 Alpha/beta hydrolase family DUF2305 PF10230.4 KKK19945.1 - 0.00054 19.4 0.0 0.17 11.3 0.0 2.3 2 0 0 2 2 2 2 Uncharacterised conserved protein (DUF2305) DUF900 PF05990.7 KKK19945.1 - 0.011 15.0 0.0 0.019 14.3 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) DUF2974 PF11187.3 KKK19945.1 - 0.12 11.7 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Peptidase_S9 PF00326.16 KKK19945.1 - 0.14 11.3 0.0 0.34 10.1 0.0 1.6 1 0 0 1 1 1 0 Prolyl oligopeptidase family Pkinase PF00069.20 KKK19947.1 - 1.1e-20 73.8 0.0 6.5e-20 71.3 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK19947.1 - 1.3e-08 34.2 0.1 0.0049 15.9 0.0 3.4 4 0 0 4 4 4 3 Protein tyrosine kinase Kdo PF06293.9 KKK19947.1 - 0.1 11.6 0.0 0.23 10.5 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Myb_DNA-bind_6 PF13921.1 KKK19948.1 - 3.2e-05 23.9 0.4 6.3e-05 23.0 0.3 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 KKK19948.1 - 0.14 12.1 0.3 0.29 11.2 0.2 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain NAPRTase PF04095.11 KKK19959.1 - 1.1e-56 191.8 0.0 1.5e-56 191.4 0.0 1.2 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family Fungal_trans PF04082.13 KKK19960.1 - 2e-27 95.7 5.5 3.5e-27 94.9 3.8 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain CTNNBL PF08216.6 KKK19963.1 - 2.7e-34 116.9 0.9 1.9e-33 114.2 0.2 2.6 2 0 0 2 2 2 1 Catenin-beta-like, Arm-motif containing nuclear Arm PF00514.18 KKK19963.1 - 0.00023 20.8 1.2 0.48 10.3 0.0 3.5 4 0 0 4 4 4 2 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 KKK19963.1 - 0.0074 16.5 8.2 0.085 13.1 0.2 4.2 3 1 1 4 4 4 1 HEAT repeats Pico_P1A PF02226.11 KKK19963.1 - 0.028 14.1 0.1 3.1 7.6 0.0 2.4 2 0 0 2 2 2 0 Picornavirus coat protein (VP4) Mo25 PF08569.6 KKK19963.1 - 0.029 13.4 0.5 0.14 11.1 0.1 2.3 1 1 1 2 2 2 0 Mo25-like MMS19_C PF12460.3 KKK19963.1 - 0.039 12.6 0.3 0.54 8.9 0.0 2.4 2 0 0 2 2 2 0 RNAPII transcription regulator C-terminal Desmo_N PF06771.6 KKK19963.1 - 0.17 11.7 0.0 4.1 7.3 0.0 2.4 2 0 0 2 2 2 0 Viral Desmoplakin N-terminus RNA_pol_Rpb2_6 PF00562.23 KKK19964.1 - 9.1e-124 413.0 0.1 1.8e-123 412.1 0.0 1.5 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 KKK19964.1 - 7e-62 207.9 0.0 1.1e-61 207.3 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 KKK19964.1 - 2.5e-46 157.5 0.0 4.6e-46 156.6 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 KKK19964.1 - 2.7e-30 104.4 0.0 7e-30 103.1 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.8 KKK19964.1 - 3.1e-24 84.5 0.8 6.8e-24 83.4 0.6 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.12 KKK19964.1 - 2.4e-23 81.8 0.5 5.5e-23 80.6 0.3 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 RNA_pol_Rpb2_3 PF04565.11 KKK19964.1 - 4.5e-23 80.7 0.6 1.5e-22 79.1 0.0 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 3 TPR_11 PF13414.1 KKK19966.1 - 1.3e-55 184.9 17.5 2e-18 65.7 0.2 6.4 3 3 4 7 7 7 7 TPR repeat TPR_1 PF00515.23 KKK19966.1 - 3e-39 131.0 18.7 3.3e-05 23.2 0.1 8.9 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_2 PF07719.12 KKK19966.1 - 5.7e-32 107.0 21.5 2.7e-05 23.7 0.2 9.8 9 1 1 10 10 10 6 Tetratricopeptide repeat TPR_12 PF13424.1 KKK19966.1 - 1.5e-21 76.1 13.6 8.9e-08 31.9 0.1 5.5 3 2 2 5 5 5 4 Tetratricopeptide repeat TPR_16 PF13432.1 KKK19966.1 - 9.7e-18 64.3 11.2 0.0055 17.3 0.2 6.6 4 1 3 7 7 7 5 Tetratricopeptide repeat TPR_14 PF13428.1 KKK19966.1 - 1.2e-12 47.2 15.1 0.24 12.1 0.3 9.3 4 3 6 10 10 9 3 Tetratricopeptide repeat TPR_8 PF13181.1 KKK19966.1 - 8.3e-12 44.0 13.4 0.043 13.6 0.0 7.0 7 1 1 8 8 7 3 Tetratricopeptide repeat TPR_19 PF14559.1 KKK19966.1 - 1.9e-10 40.9 16.0 0.1 12.9 0.0 7.0 4 3 2 7 7 6 3 Tetratricopeptide repeat TPR_17 PF13431.1 KKK19966.1 - 7.4e-09 35.1 4.5 1.9 8.8 0.0 7.2 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_9 PF13371.1 KKK19966.1 - 7.8e-08 32.0 12.6 0.0005 19.8 0.1 5.0 4 1 2 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.1 KKK19966.1 - 1.2e-07 31.0 13.9 0.02 14.6 0.2 8.5 9 1 0 9 9 8 1 Tetratricopeptide repeat Apc3 PF12895.2 KKK19966.1 - 5.3e-07 29.6 7.2 0.0011 19.0 0.1 4.1 3 1 1 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.1 KKK19966.1 - 5.3e-05 23.0 0.8 0.21 11.4 0.0 4.9 5 0 0 5 5 5 1 Fis1 C-terminal tetratricopeptide repeat SHNi-TPR PF10516.4 KKK19966.1 - 0.0007 18.7 7.9 1.8 7.8 0.0 5.2 6 0 0 6 6 6 2 SHNi-TPR NARP1 PF12569.3 KKK19966.1 - 0.016 13.9 0.1 0.016 13.9 0.0 3.9 4 0 0 4 4 4 0 NMDA receptor-regulated protein 1 Inhibitor_I9 PF05922.11 KKK19966.1 - 0.022 15.3 0.2 0.091 13.3 0.0 2.2 2 0 0 2 2 2 0 Peptidase inhibitor I9 TPR_6 PF13174.1 KKK19966.1 - 0.038 14.4 18.8 1.3 9.6 0.0 7.9 9 0 0 9 9 8 0 Tetratricopeptide repeat TPR_10 PF13374.1 KKK19966.1 - 0.11 12.5 8.8 39 4.3 0.0 5.6 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_20 PF14561.1 KKK19966.1 - 0.12 12.5 0.1 0.12 12.5 0.1 5.6 4 2 3 7 7 7 0 Tetratricopeptide repeat ING PF12998.2 KKK19967.1 - 5.8e-24 84.3 7.3 1.1e-23 83.4 5.1 1.5 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 KKK19967.1 - 7.1e-09 35.2 9.7 1.2e-08 34.4 6.8 1.4 1 0 0 1 1 1 1 PHD-finger DUF4200 PF13863.1 KKK19967.1 - 0.029 14.3 4.9 2.5 8.0 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) FGF-BP1 PF06473.7 KKK19967.1 - 1.5 8.3 8.4 0.35 10.4 3.1 1.9 2 0 0 2 2 2 0 FGF binding protein 1 (FGF-BP1) zf-RING-like PF08746.6 KKK19967.1 - 4.4 7.3 7.6 9.6 6.2 5.2 1.6 1 0 0 1 1 1 0 RING-like domain RNA_pol_Rpc34 PF05158.7 KKK19968.1 - 7.2e-123 409.9 0.0 8.1e-123 409.7 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit TrmB PF01978.14 KKK19968.1 - 0.042 13.5 0.0 0.1 12.3 0.0 1.6 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB MarR PF01047.17 KKK19968.1 - 0.072 12.7 0.0 0.24 11.1 0.0 1.9 2 0 0 2 2 2 0 MarR family TrmE_N PF10396.4 KKK19968.1 - 0.073 13.0 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 GTP-binding protein TrmE N-terminus HTH_36 PF13730.1 KKK19968.1 - 0.098 12.8 0.0 0.22 11.6 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain Na_H_Exchanger PF00999.16 KKK19969.1 - 7.8e-38 129.9 16.3 9.9e-38 129.6 11.3 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family YrhC PF14143.1 KKK19969.1 - 0.0066 16.3 1.2 0.67 9.9 0.0 3.4 3 0 0 3 3 3 1 YrhC-like protein Lipoprotein_18 PF06804.6 KKK19969.1 - 0.026 13.2 0.0 0.039 12.6 0.0 1.1 1 0 0 1 1 1 0 NlpB/DapX lipoprotein DUF3329 PF11808.3 KKK19969.1 - 3.8 7.6 5.1 2.2 8.4 0.3 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF3329) PEPCK_ATP PF01293.15 KKK19970.1 - 8.6e-216 716.9 0.0 1e-215 716.6 0.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_18 PF13238.1 KKK19970.1 - 0.031 14.5 0.0 7.5 6.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 KKK19970.1 - 0.042 13.2 0.0 0.3 10.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 KKK19970.1 - 0.086 12.7 0.1 0.23 11.3 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 KKK19970.1 - 0.19 11.7 0.0 0.37 10.7 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain NB-ARC PF00931.17 KKK19971.1 - 2.5e-13 49.5 0.0 5.8e-13 48.3 0.0 1.5 1 1 0 1 1 1 1 NB-ARC domain TPR_12 PF13424.1 KKK19971.1 - 5.2e-12 45.5 2.7 1.3e-07 31.4 0.0 4.1 3 1 1 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.1 KKK19971.1 - 4.2e-11 42.3 0.8 0.00013 21.5 0.0 4.0 4 0 0 4 4 4 2 TPR repeat TPR_2 PF07719.12 KKK19971.1 - 6.3e-05 22.6 3.7 0.054 13.4 0.1 5.0 5 0 0 5 5 4 1 Tetratricopeptide repeat AAA_22 PF13401.1 KKK19971.1 - 0.00019 21.5 0.0 0.0033 17.5 0.0 2.7 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.1 KKK19971.1 - 0.00032 20.7 0.1 0.0016 18.4 0.0 2.3 2 1 0 2 2 2 1 AAA ATPase domain TPR_16 PF13432.1 KKK19971.1 - 0.00053 20.5 2.3 0.0014 19.2 0.6 2.6 2 1 0 2 2 1 1 Tetratricopeptide repeat TPR_1 PF00515.23 KKK19971.1 - 0.001 18.5 1.1 0.012 15.1 0.0 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat NACHT PF05729.7 KKK19971.1 - 0.0066 16.1 0.1 0.078 12.6 0.1 2.7 1 1 0 1 1 1 1 NACHT domain TPR_14 PF13428.1 KKK19971.1 - 0.01 16.3 0.6 3.7 8.4 0.0 4.0 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.1 KKK19971.1 - 0.011 15.6 0.5 0.049 13.5 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.1 KKK19971.1 - 0.031 14.0 0.9 0.54 10.1 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.9 KKK19971.1 - 0.042 14.2 0.7 29 5.4 0.0 3.3 3 0 0 3 3 2 0 Tetratricopeptide repeat PEX11 PF05648.9 KKK19972.1 - 2.1e-74 249.5 0.6 2.4e-74 249.3 0.4 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Mito_carr PF00153.22 KKK19973.1 - 7.8e-56 185.7 3.1 2.2e-21 75.3 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein zf-Nse PF11789.3 KKK19974.1 - 7.1e-23 79.8 0.1 1.2e-22 79.1 0.1 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_2 PF13639.1 KKK19974.1 - 0.00024 20.8 0.1 0.00039 20.1 0.1 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.1 KKK19974.1 - 0.0052 16.4 0.2 0.043 13.5 0.0 2.4 1 1 1 2 2 2 1 RING-type zinc-finger zf-MIZ PF02891.15 KKK19974.1 - 0.042 13.3 2.1 0.2 11.1 0.1 2.2 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger DUF1943 PF09172.6 KKK19974.1 - 0.17 10.7 2.3 0.35 9.6 1.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) Aminotran_1_2 PF00155.16 KKK19975.1 - 2.3e-41 141.9 0.0 3.2e-41 141.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Copper-fist PF00649.13 KKK19976.1 - 5.7e-22 76.6 2.8 5.7e-22 76.6 2.0 2.8 2 1 1 3 3 3 1 Copper fist DNA binding domain LEDGF PF11467.3 KKK19977.1 - 0.029 14.0 0.0 0.051 13.2 0.0 1.3 1 0 0 1 1 1 0 Lens epithelium-derived growth factor (LEDGF) RPN7 PF10602.4 KKK19978.1 - 7.3e-53 178.5 0.6 1.1e-52 177.9 0.4 1.3 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 KKK19978.1 - 8.4e-16 58.1 0.1 2.6e-15 56.6 0.0 1.9 2 0 0 2 2 2 1 PCI domain CytochromB561_N PF09786.4 KKK19978.1 - 0.049 12.0 0.1 0.067 11.6 0.1 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal TPR_7 PF13176.1 KKK19978.1 - 0.062 13.1 0.2 0.34 10.7 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat LSM PF01423.17 KKK19979.1 - 8.8e-06 25.1 0.0 1.2e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 LSM domain zf-BED PF02892.10 KKK19999.1 - 1.2e-07 31.3 2.9 0.0051 16.5 0.3 2.3 2 0 0 2 2 2 2 BED zinc finger DUF3237 PF11578.3 KKK19999.1 - 4.1e-07 29.4 0.0 6.7e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) zf-C2H2_2 PF12756.2 KKK19999.1 - 0.0066 16.5 4.8 0.64 10.1 0.1 2.2 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) Herpes_capsid PF06112.6 KKK19999.1 - 0.013 15.5 14.1 7.1 6.6 9.8 2.9 2 1 0 2 2 2 0 Gammaherpesvirus capsid protein Tmemb_55A PF09788.4 KKK19999.1 - 0.018 14.1 8.1 0.066 12.3 1.0 2.3 2 1 0 2 2 2 0 Transmembrane protein 55A TFIIA PF03153.8 KKK19999.1 - 0.27 11.1 6.0 0.32 10.8 4.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.4 KKK19999.1 - 9.4 4.3 9.9 12 4.0 6.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PPR_2 PF13041.1 KKK20011.1 - 1.6e-09 37.5 0.1 0.0078 16.1 0.0 4.5 3 2 2 5 5 5 3 PPR repeat family PPR PF01535.15 KKK20011.1 - 8e-08 31.7 1.0 0.062 13.3 0.0 4.5 4 0 0 4 4 4 2 PPR repeat PPR_3 PF13812.1 KKK20011.1 - 1.5e-05 24.8 0.2 2.1 8.8 0.0 5.2 6 0 0 6 6 6 2 Pentatricopeptide repeat domain TPR_14 PF13428.1 KKK20011.1 - 0.034 14.7 0.0 4.5 8.1 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat PaREP1 PF05942.6 KKK20011.1 - 0.059 13.2 0.1 0.2 11.5 0.1 1.8 1 0 0 1 1 1 0 Archaeal PaREP1/PaREP8 family Helicase_C PF00271.26 KKK20012.1 - 1.2e-17 63.4 0.0 6.6e-14 51.5 0.0 3.7 3 1 0 3 3 3 2 Helicase conserved C-terminal domain DEAD PF00270.24 KKK20012.1 - 4.9e-12 45.6 0.0 1.4e-09 37.7 0.0 2.5 1 1 0 1 1 1 1 DEAD/DEAH box helicase CDK2AP PF09806.4 KKK20012.1 - 0.019 15.1 6.4 0.16 12.2 2.3 2.4 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein PEHE PF15275.1 KKK20012.1 - 0.32 11.4 0.1 0.32 11.4 0.0 2.6 2 1 0 2 2 2 0 PEHE domain SR-25 PF10500.4 KKK20012.1 - 1.3 8.4 19.6 0.041 13.3 9.0 1.8 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF2217 PF10265.4 KKK20012.1 - 3.1 6.4 5.5 5.8 5.5 3.8 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) RAP1 PF07218.6 KKK20012.1 - 8.6 4.3 8.1 13 3.7 5.6 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) SelP_N PF04592.9 KKK20013.1 - 0.036 13.4 1.0 0.053 12.8 0.7 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region DUF4587 PF15248.1 KKK20013.1 - 0.19 12.3 1.7 0.46 11.1 1.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4587) Ydc2-catalyt PF09159.5 KKK20014.1 - 1.5e-80 270.6 0.0 1.9e-80 270.3 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 SAP PF02037.22 KKK20014.1 - 8.3e-06 25.1 0.0 3.9e-05 23.0 0.0 2.0 2 0 0 2 2 2 1 SAP domain Pox_A22 PF04848.8 KKK20014.1 - 0.00046 20.0 0.0 1.2 8.9 0.0 3.2 3 0 0 3 3 3 1 Poxvirus A22 protein PLRV_ORF5 PF01690.12 KKK20014.1 - 6 5.8 12.9 11 5.0 9.0 1.3 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Maff2 PF12750.2 KKK20015.1 - 0.058 12.9 0.1 0.1 12.1 0.1 1.4 1 0 0 1 1 1 0 Maff2 family Osmo_CC PF08946.5 KKK20015.1 - 0.069 13.1 1.6 0.11 12.4 1.1 1.3 1 0 0 1 1 1 0 Osmosensory transporter coiled coil DUF533 PF04391.7 KKK20015.1 - 0.11 11.8 0.5 0.3 10.4 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF533) CTP_transf_2 PF01467.21 KKK20016.1 - 0.00031 20.8 0.0 0.0015 18.6 0.0 2.1 2 1 0 2 2 2 1 Cytidylyltransferase SOG2 PF10428.4 KKK20017.1 - 6.6e-131 437.0 0.1 2.3e-130 435.2 0.0 1.9 2 0 0 2 2 2 1 RAM signalling pathway protein LRR_4 PF12799.2 KKK20017.1 - 9.7e-15 53.8 5.5 1.5e-08 34.0 2.1 3.9 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KKK20017.1 - 2.1e-12 46.6 4.7 2e-06 27.4 1.4 3.0 1 1 2 3 3 3 3 Leucine rich repeat LRR_1 PF00560.28 KKK20017.1 - 2.5e-09 35.8 6.7 0.043 13.8 0.1 6.4 6 0 0 6 6 6 3 Leucine Rich Repeat LRR_7 PF13504.1 KKK20017.1 - 4e-06 26.1 5.3 1.7 9.2 0.0 5.8 5 0 0 5 5 5 2 Leucine rich repeat LRR_6 PF13516.1 KKK20017.1 - 0.015 15.3 4.6 5.9 7.2 0.0 4.6 4 1 0 4 4 4 0 Leucine Rich repeat MRP-S25 PF13741.1 KKK20018.1 - 1.2e-87 293.2 9.9 1.3e-87 293.0 6.8 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein S25 Tcp11 PF05794.8 KKK20019.1 - 5.3e-140 467.0 0.0 6.7e-140 466.6 0.0 1.0 1 0 0 1 1 1 1 T-complex protein 11 DUF566 PF04484.7 KKK20019.1 - 0.38 10.2 2.5 0.64 9.4 1.7 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF566) KcnmB2_inactiv PF09303.5 KKK20019.1 - 1.1 9.1 3.3 0.64 9.8 0.4 2.0 2 0 0 2 2 2 0 KCNMB2, ball and chain domain Pol_alpha_B_N PF08418.5 KKK20019.1 - 2.2 7.7 5.1 3.6 7.0 3.6 1.3 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Peptidase_S10 PF00450.17 KKK20020.1 - 1.1e-76 258.6 0.0 8.2e-76 255.8 0.0 2.2 1 1 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 KKK20020.1 - 1.5e-07 31.5 1.0 0.00032 20.6 0.0 2.5 2 1 0 2 2 2 2 Alpha/beta hydrolase family DUF3984 PF13136.1 KKK20021.1 - 5e-102 341.4 26.8 5e-102 341.4 18.6 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3984) Transposase_24 PF03004.9 KKK20021.1 - 0.00074 19.4 1.3 0.0023 17.7 0.9 1.9 1 0 0 1 1 1 1 Plant transposase (Ptta/En/Spm family) Glycoprotein PF03409.10 KKK20021.1 - 4 6.0 8.5 6.8 5.3 5.9 1.2 1 0 0 1 1 1 0 Transmembrane glycoprotein OTCace_N PF02729.16 KKK20022.1 - 4.4e-43 146.3 0.0 8.8e-43 145.3 0.0 1.5 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.19 KKK20022.1 - 1.7e-40 138.4 0.0 2.7e-40 137.8 0.0 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain ALS_ss_C PF10369.4 KKK20023.1 - 4.5e-19 67.9 0.0 8.1e-18 63.9 0.0 2.3 2 0 0 2 2 2 1 Small subunit of acetolactate synthase ACT PF01842.20 KKK20023.1 - 8.2e-11 41.1 0.1 1.4e-10 40.4 0.1 1.4 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.1 KKK20023.1 - 2.9e-09 36.6 0.0 5.8e-09 35.6 0.0 1.6 1 0 0 1 1 1 1 ACT domain ACT_6 PF13740.1 KKK20023.1 - 0.014 15.0 0.1 3 7.6 0.0 2.7 2 0 0 2 2 2 0 ACT domain KH_1 PF00013.24 KKK20024.1 - 1e-10 41.1 0.0 9.9e-07 28.3 0.0 2.4 2 0 0 2 2 2 2 KH domain KH_3 PF13014.1 KKK20024.1 - 2.1e-06 27.2 2.6 0.00019 21.0 0.1 3.2 3 0 0 3 3 3 2 KH domain Fmp27 PF10344.4 KKK20025.1 - 8.1e-248 824.5 0.0 5.4e-247 821.8 0.0 2.1 2 0 0 2 2 2 1 Mitochondrial protein from FMP27 Apt1 PF10351.4 KKK20025.1 - 1.1e-171 571.7 0.7 1.1e-171 571.7 0.5 2.6 3 0 0 3 3 3 1 Golgi-body localisation protein domain Fmp27_WPPW PF10359.4 KKK20025.1 - 1.8e-154 514.6 4.3 4.7e-154 513.3 3.0 1.8 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.4 KKK20025.1 - 3.6e-60 202.2 0.3 8.6e-60 201.0 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF2405) Fmp27_GFWDK PF10347.4 KKK20025.1 - 7.5e-52 175.3 0.0 1.8e-51 174.1 0.0 1.7 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain Fmp27_SW PF10305.4 KKK20025.1 - 4.7e-33 113.6 0.0 4.3e-32 110.6 0.0 2.6 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain LEA_2 PF03168.8 KKK20027.1 - 3.4e-10 40.2 4.1 0.0059 16.9 0.0 5.0 5 1 0 5 5 5 3 Late embryogenesis abundant protein DUF3712 PF12505.3 KKK20027.1 - 2.2e-06 27.7 0.4 1.5e-05 25.0 0.1 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF3712) SET PF00856.23 KKK20030.1 - 2.6e-19 70.1 2.0 2.9e-19 69.9 0.1 2.0 2 1 0 2 2 2 1 SET domain Pre-SET PF05033.11 KKK20030.1 - 1.9e-16 60.2 7.2 1.9e-16 60.1 2.4 2.4 2 0 0 2 2 2 1 Pre-SET motif Alveol-reg_P311 PF11092.3 KKK20030.1 - 0.12 12.3 0.3 0.44 10.5 0.0 2.1 3 0 0 3 3 3 0 Neuronal protein 3.1 (p311) Dishevelled PF02377.10 KKK20030.1 - 0.14 12.3 3.4 0.38 10.9 2.3 1.8 1 1 0 1 1 1 0 Dishevelled specific domain SARA PF11409.3 KKK20031.1 - 1.1 9.2 7.1 4.1 7.4 4.9 2.1 1 1 0 1 1 1 0 Smad anchor for receptor activation (SARA) Ytp1 PF10355.4 KKK20050.1 - 4.8e-113 376.8 9.6 6.7e-113 376.3 6.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 KKK20050.1 - 6.7e-21 73.8 10.7 3.2e-19 68.4 2.0 2.7 2 0 0 2 2 2 2 Domain of unknown function (DUF2427) PCI PF01399.22 KKK20051.1 - 1.1e-08 35.3 0.0 2.6e-08 34.1 0.0 1.7 1 0 0 1 1 1 1 PCI domain GrpE PF01025.14 KKK20051.1 - 0.011 15.2 0.4 0.022 14.3 0.3 1.4 1 0 0 1 1 1 0 GrpE Gaa1 PF04114.9 KKK20052.1 - 1.6e-95 320.7 4.4 6.3e-95 318.7 3.1 1.8 1 1 0 1 1 1 1 Gaa1-like, GPI transamidase component Rhomboid PF01694.17 KKK20052.1 - 4.6e-13 49.4 10.4 4.6e-13 49.4 7.2 3.4 4 0 0 4 4 4 1 Rhomboid family DLH PF01738.13 KKK20053.1 - 2.6e-33 115.1 0.0 3e-33 114.9 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 KKK20053.1 - 4e-06 26.6 0.0 5.6e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KKK20053.1 - 0.0019 18.1 0.0 0.011 15.6 0.0 1.7 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KKK20053.1 - 0.0089 15.6 0.0 0.017 14.6 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Acetyltransf_8 PF13523.1 KKK20057.1 - 2.9e-23 82.4 0.4 3.7e-15 56.1 0.0 2.2 1 1 1 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 KKK20057.1 - 0.093 12.8 0.1 0.42 10.7 0.1 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Mor PF08765.6 KKK20058.1 - 0.14 11.9 0.1 0.31 10.8 0.1 1.5 1 0 0 1 1 1 0 Mor transcription activator family ABC_membrane PF00664.18 KKK20059.1 - 7.6e-79 264.9 21.7 2e-46 158.6 2.3 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KKK20059.1 - 3.5e-61 205.4 0.0 9.6e-30 103.6 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 KKK20059.1 - 3.2e-16 59.2 1.5 6.4e-05 22.2 0.0 4.3 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 KKK20059.1 - 3.7e-09 35.9 0.1 0.0015 17.9 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.1 KKK20059.1 - 7.7e-08 32.6 0.0 0.49 10.3 0.0 4.6 3 1 0 4 4 4 1 AAA domain AAA_17 PF13207.1 KKK20059.1 - 4.7e-07 30.6 0.0 0.055 14.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 KKK20059.1 - 6.8e-07 29.4 1.9 0.015 15.2 0.0 2.9 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 KKK20059.1 - 7e-07 29.4 2.0 0.1 12.7 0.1 4.4 2 2 0 2 2 2 2 AAA domain DUF87 PF01935.12 KKK20059.1 - 2e-05 24.5 0.4 0.0058 16.4 0.1 2.6 2 1 0 2 2 2 1 Domain of unknown function DUF87 DUF258 PF03193.11 KKK20059.1 - 2e-05 23.8 0.0 0.033 13.3 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_23 PF13476.1 KKK20059.1 - 3.9e-05 24.0 3.4 0.12 12.6 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_30 PF13604.1 KKK20059.1 - 0.00011 21.8 0.2 2.5 7.6 0.0 4.2 4 0 0 4 4 4 1 AAA domain APS_kinase PF01583.15 KKK20059.1 - 0.00014 21.5 0.0 0.13 11.9 0.0 2.6 2 0 0 2 2 2 1 Adenylylsulphate kinase AAA_18 PF13238.1 KKK20059.1 - 0.00018 21.7 0.0 0.86 9.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 KKK20059.1 - 0.00024 21.0 0.0 0.81 9.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain ABC_ATPase PF09818.4 KKK20059.1 - 0.00025 19.7 1.0 0.026 13.1 0.0 2.6 3 0 0 3 3 3 1 Predicted ATPase of the ABC class AAA_19 PF13245.1 KKK20059.1 - 0.00043 19.9 0.1 0.51 10.1 0.0 2.9 2 0 0 2 2 2 1 Part of AAA domain AAA PF00004.24 KKK20059.1 - 0.001 19.2 0.9 9.4 6.4 0.2 4.2 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 KKK20059.1 - 0.0011 18.4 1.1 0.29 10.5 0.0 3.2 4 0 0 4 4 4 1 AAA-like domain Zeta_toxin PF06414.7 KKK20059.1 - 0.0014 17.7 0.0 0.4 9.7 0.0 2.8 3 0 0 3 3 3 1 Zeta toxin SbcCD_C PF13558.1 KKK20059.1 - 0.0029 17.4 0.3 5.4 7.0 0.1 3.4 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_25 PF13481.1 KKK20059.1 - 0.0082 15.5 3.9 1.7 7.9 0.0 4.0 5 0 0 5 5 4 1 AAA domain FtsK_SpoIIIE PF01580.13 KKK20059.1 - 0.02 14.3 0.0 0.31 10.4 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_14 PF13173.1 KKK20059.1 - 0.05 13.5 0.0 17 5.3 0.0 3.0 3 0 0 3 3 2 0 AAA domain G-alpha PF00503.15 KKK20059.1 - 0.055 12.1 2.3 7.8 5.0 0.0 3.0 3 0 0 3 3 3 0 G-protein alpha subunit KdpD PF02702.12 KKK20059.1 - 0.059 12.5 0.0 0.53 9.3 0.0 2.2 2 0 0 2 2 2 0 Osmosensitive K+ channel His kinase sensor domain DUF3987 PF13148.1 KKK20059.1 - 0.066 11.7 5.4 2 6.8 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3987) AAA_5 PF07728.9 KKK20059.1 - 0.071 12.8 0.0 13 5.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) MMR_HSR1 PF01926.18 KKK20059.1 - 0.099 12.6 0.0 20 5.1 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase Nucleoplasmin PF03066.10 KKK20059.1 - 0.26 10.7 5.4 0.49 9.9 3.7 1.4 1 0 0 1 1 1 0 Nucleoplasmin Ribosomal_60s PF00428.14 KKK20059.1 - 0.3 11.5 10.5 1.2 9.5 7.3 2.0 1 0 0 1 1 1 0 60s Acidic ribosomal protein CENP-B_dimeris PF09026.5 KKK20059.1 - 0.82 9.9 6.0 2.2 8.5 4.1 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DDHD PF02862.12 KKK20059.1 - 1.2 8.9 2.9 2.8 7.6 2.0 1.6 1 0 0 1 1 1 0 DDHD domain MFS_1 PF07690.11 KKK20060.1 - 5.1e-25 87.9 43.9 2.2e-23 82.5 29.7 2.7 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 KKK20060.1 - 0.00018 19.8 9.2 0.00018 19.8 6.4 2.3 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Ald_Xan_dh_C2 PF02738.13 KKK20061.1 - 2.3e-198 659.9 1.1 3.2e-198 659.5 0.8 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.16 KKK20061.1 - 4.7e-48 162.8 0.0 8.7e-48 161.9 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Ald_Xan_dh_C PF01315.17 KKK20061.1 - 6.6e-34 116.3 0.0 1.4e-33 115.2 0.0 1.6 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain CO_deh_flav_C PF03450.12 KKK20061.1 - 7.3e-32 109.3 0.0 3.8e-31 107.0 0.0 2.3 2 0 0 2 2 2 1 CO dehydrogenase flavoprotein C-terminal domain Fer2_2 PF01799.15 KKK20061.1 - 9.3e-29 99.1 0.0 1.9e-28 98.1 0.0 1.6 1 0 0 1 1 1 1 [2Fe-2S] binding domain Fer2 PF00111.22 KKK20061.1 - 2.7e-08 33.4 0.1 2.7e-08 33.4 0.1 2.4 3 0 0 3 3 3 1 2Fe-2S iron-sulfur cluster binding domain Baculo_PEP_C PF04513.7 KKK20062.1 - 0.0071 16.1 7.6 0.13 12.1 0.3 3.3 3 1 1 4 4 4 2 Baculovirus polyhedron envelope protein, PEP, C terminus Sec8_exocyst PF04048.9 KKK20062.1 - 0.044 13.4 0.3 7.7 6.1 0.0 2.7 2 1 1 3 3 3 0 Sec8 exocyst complex component specific domain DUF2135 PF09906.4 KKK20062.1 - 0.13 12.2 0.4 0.4 10.6 0.1 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2135) CDC45 PF02724.9 KKK20063.1 - 0.33 8.9 7.7 0.41 8.6 5.3 1.1 1 0 0 1 1 1 0 CDC45-like protein TSGP1 PF07771.6 KKK20063.1 - 1.3 8.9 4.7 2.3 8.1 3.3 1.4 1 0 0 1 1 1 0 Tick salivary peptide group 1 NAD_binding_4 PF07993.7 KKK20064.1 - 9.5e-33 113.1 0.0 1.4e-32 112.6 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.14 KKK20064.1 - 3e-05 22.8 0.0 0.00018 20.3 0.0 1.9 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family GET2 PF08690.5 KKK20064.1 - 0.0002 20.7 0.0 0.00033 20.0 0.0 1.2 1 0 0 1 1 1 1 GET complex subunit GET2 adh_short PF00106.20 KKK20064.1 - 0.00037 20.4 0.0 0.00088 19.2 0.0 1.7 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 KKK20064.1 - 0.00065 19.1 0.0 0.0016 17.9 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 KKK20064.1 - 0.0054 16.4 0.0 0.014 15.1 0.0 1.6 1 0 0 1 1 1 1 KR domain DUF1413 PF07205.6 KKK20064.1 - 0.22 11.0 0.1 0.44 10.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1413) SOG2 PF10428.4 KKK20064.1 - 0.84 8.2 4.3 1.4 7.4 3.0 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein AMP-binding PF00501.23 KKK20065.1 - 1.4e-65 221.2 0.1 2e-61 207.6 0.0 2.0 2 0 0 2 2 2 2 AMP-binding enzyme C2 PF00168.25 KKK20066.1 - 1.7e-20 72.6 0.0 6.3e-15 54.7 0.0 2.7 2 0 0 2 2 2 2 C2 domain Reprolysin_5 PF13688.1 KKK20067.1 - 2.2e-61 207.2 9.8 2.2e-61 207.2 6.8 2.5 2 1 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.1 KKK20067.1 - 3.2e-46 157.4 4.3 3.2e-46 157.4 3.0 1.6 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 KKK20067.1 - 2.5e-45 154.6 5.8 2.5e-45 154.6 4.0 2.1 3 0 0 3 3 3 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 KKK20067.1 - 7.5e-21 74.9 0.4 3.3e-20 72.8 0.3 2.2 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.18 KKK20067.1 - 2.8e-19 69.1 33.5 2.8e-19 69.1 23.2 4.9 2 2 2 4 4 4 1 Disintegrin Pep_M12B_propep PF01562.14 KKK20067.1 - 0.00033 20.4 0.1 0.0012 18.6 0.0 1.9 1 0 0 1 1 1 1 Reprolysin family propeptide IMS PF00817.15 KKK20068.1 - 6.9e-38 129.7 0.0 2.4e-37 128.0 0.0 1.8 2 0 0 2 2 2 1 impB/mucB/samB family IMS_C PF11799.3 KKK20068.1 - 8.5e-10 38.6 0.2 8.4e-09 35.4 0.1 2.3 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 KKK20068.1 - 0.0002 21.1 0.0 0.00049 19.9 0.0 1.7 1 0 0 1 1 1 1 IMS family HHH motif MgsA_C PF12002.3 KKK20069.1 - 5.9e-59 198.5 0.3 1.7e-58 197.0 0.1 1.8 2 0 0 2 2 2 1 MgsA AAA+ ATPase C terminal AAA PF00004.24 KKK20069.1 - 5.5e-15 55.7 0.0 1.3e-14 54.5 0.0 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 KKK20069.1 - 1.1e-11 44.2 0.0 4.8e-11 42.1 0.0 1.8 1 1 1 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 KKK20069.1 - 6.5e-06 25.8 0.0 2.1e-05 24.1 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain Mg_chelatase PF01078.16 KKK20069.1 - 8.1e-06 25.1 0.1 0.065 12.3 0.0 2.3 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 KKK20069.1 - 1e-05 25.2 0.0 0.00011 21.8 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 KKK20069.1 - 1.3e-05 24.7 0.0 7.7e-05 22.3 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 KKK20069.1 - 0.00015 21.3 0.0 0.0075 15.7 0.0 2.3 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_22 PF13401.1 KKK20069.1 - 0.00065 19.8 0.1 0.0031 17.6 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KKK20069.1 - 0.0031 17.4 0.0 0.006 16.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KKK20069.1 - 0.0038 17.2 0.2 0.22 11.5 0.0 3.1 2 1 1 3 3 3 1 AAA ATPase domain Sigma54_activ_2 PF14532.1 KKK20069.1 - 0.0042 17.1 0.0 0.0095 15.9 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain TIP49 PF06068.8 KKK20069.1 - 0.0043 15.8 0.0 0.036 12.7 0.0 2.0 2 0 0 2 2 2 1 TIP49 C-terminus AAA_17 PF13207.1 KKK20069.1 - 0.0069 17.1 0.0 0.02 15.7 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_18 PF13238.1 KKK20069.1 - 0.0077 16.5 0.0 0.015 15.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.8 KKK20069.1 - 0.011 14.7 0.0 0.017 14.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) ResIII PF04851.10 KKK20069.1 - 0.021 14.6 0.2 1.9 8.3 0.0 2.2 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit AAA_28 PF13521.1 KKK20069.1 - 0.023 14.6 0.1 0.056 13.4 0.1 1.7 1 0 0 1 1 1 0 AAA domain DUF927 PF06048.6 KKK20069.1 - 0.056 12.6 0.1 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF927) AAA_10 PF12846.2 KKK20069.1 - 0.059 12.7 0.5 16 4.7 0.0 3.0 2 1 0 2 2 2 0 AAA-like domain SKI PF01202.17 KKK20069.1 - 0.068 13.0 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Shikimate kinase RNA_helicase PF00910.17 KKK20069.1 - 0.11 12.6 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 RNA helicase CPT PF07931.7 KKK20069.1 - 0.11 12.1 0.1 0.5 9.9 0.0 1.9 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein Zeta_toxin PF06414.7 KKK20069.1 - 0.16 11.0 0.0 0.32 10.0 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin EF-hand_1 PF00036.27 KKK20070.1 - 5.5e-15 53.4 1.2 7.7e-05 21.7 0.0 3.5 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.1 KKK20070.1 - 8e-15 54.7 0.3 1.7e-08 34.4 0.1 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 KKK20070.1 - 1.3e-13 49.5 4.4 9.4e-06 25.1 0.1 3.4 4 0 0 4 4 4 2 EF-hand domain EF-hand_8 PF13833.1 KKK20070.1 - 4.6e-11 42.1 0.7 1.5e-08 34.1 0.1 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 KKK20070.1 - 0.1 11.9 7.0 0.88 9.0 0.1 3.1 3 0 0 3 3 3 0 EF hand MerR-DNA-bind PF09278.6 KKK20070.1 - 0.12 12.7 3.0 1.1 9.7 0.1 3.0 3 0 0 3 3 3 0 MerR, DNA binding EF-hand_4 PF12763.2 KKK20070.1 - 0.16 11.7 0.0 0.4 10.4 0.0 1.6 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand zf-MYND PF01753.13 KKK20071.1 - 0.015 15.1 8.8 0.043 13.7 6.1 1.9 1 0 0 1 1 1 0 MYND finger Aminotran_1_2 PF00155.16 KKK20072.1 - 2e-57 194.8 0.0 4e-57 193.8 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 KKK20072.1 - 0.00015 20.9 0.0 0.00022 20.4 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 KKK20072.1 - 0.0048 15.2 0.0 0.007 14.6 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 KKK20072.1 - 0.013 14.5 0.0 0.024 13.6 0.0 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.14 KKK20072.1 - 0.033 12.9 0.0 0.049 12.3 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V RNA_pol_Rpb4 PF03874.11 KKK20074.1 - 1.6e-07 31.3 0.0 0.00075 19.4 0.0 2.3 2 0 0 2 2 2 2 RNA polymerase Rpb4 PKI PF02827.11 KKK20074.1 - 1.1 9.3 4.2 2.8 8.1 2.9 1.6 1 0 0 1 1 1 0 cAMP-dependent protein kinase inhibitor Dicty_REP PF05086.7 KKK20076.1 - 0.056 11.2 1.0 0.065 10.9 0.7 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein APH PF01636.18 KKK20077.1 - 7.4e-15 55.3 0.4 2.6e-14 53.5 0.2 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.9 KKK20077.1 - 0.0044 16.0 0.0 0.0084 15.1 0.0 1.4 1 0 0 1 1 1 1 Fructosamine kinase vATP-synt_AC39 PF01992.11 KKK20078.1 - 1.1e-105 353.4 0.0 1.3e-105 353.2 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit Nop PF01798.13 KKK20079.1 - 1.1e-54 183.8 0.6 2.2e-54 182.8 0.4 1.6 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 KKK20079.1 - 1e-26 92.4 0.1 2e-26 91.5 0.0 1.5 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 KKK20079.1 - 4.6e-23 81.1 2.6 2.4e-22 78.8 1.8 2.4 1 0 0 1 1 1 1 NOP5NT (NUC127) domain HWE_HK PF07536.9 KKK20079.1 - 0.058 13.8 0.8 35 4.9 0.0 3.5 3 0 0 3 3 3 0 HWE histidine kinase Ribosomal_S15 PF00312.17 KKK20080.1 - 7.3e-20 70.5 0.7 2.2e-19 68.9 0.1 2.1 2 0 0 2 2 2 1 Ribosomal protein S15 CytochromB561_N PF09786.4 KKK20080.1 - 0.055 11.9 2.0 0.073 11.5 1.4 1.2 1 0 0 1 1 1 0 Cytochrome B561, N terminal SOBP PF15279.1 KKK20081.1 - 0.042 14.2 16.0 0.052 13.9 11.1 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein SAGA-Tad1 PF12767.2 KKK20081.1 - 0.058 13.0 7.1 0.075 12.6 4.9 1.3 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit DUF2992 PF11208.3 KKK20081.1 - 3.2 7.6 9.2 4.3 7.2 5.9 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2992) KIAA1328 PF15369.1 KKK20081.1 - 6.4 6.4 15.2 8.8 6.0 10.5 1.1 1 0 0 1 1 1 0 Uncharacterised protein KIAA1328 Mitofilin PF09731.4 KKK20081.1 - 7 5.1 20.4 9.2 4.7 14.1 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Peptidase_S64 PF08192.6 KKK20081.1 - 7.4 4.7 12.0 9 4.4 8.3 1.1 1 0 0 1 1 1 0 Peptidase family S64 PseudoU_synth_1 PF01416.15 KKK20082.1 - 1.1e-28 99.7 0.0 3.2e-21 75.7 0.0 2.8 3 0 0 3 3 3 2 tRNA pseudouridine synthase Pribosyl_synth PF14572.1 KKK20083.1 - 5.1e-40 137.1 2.9 3.3e-35 121.4 0.6 2.3 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.1 KKK20083.1 - 1.3e-31 108.6 0.0 4e-31 107.1 0.0 1.8 1 0 0 1 1 1 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.22 KKK20083.1 - 1.4e-10 40.9 0.3 3.8e-10 39.5 0.2 1.7 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 KKK20083.1 - 0.0014 17.9 0.3 0.0023 17.1 0.2 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Ribosomal_S2 PF00318.15 KKK20084.1 - 1.2e-43 148.7 0.0 4.8e-23 81.4 0.0 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 Ras PF00071.17 KKK20085.1 - 4.9e-18 65.0 0.0 1.2e-17 63.7 0.0 1.6 1 1 0 1 1 1 1 Ras family Miro PF08477.8 KKK20085.1 - 2.6e-08 34.3 0.0 3.9e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein MCM PF00493.18 KKK20085.1 - 0.0015 17.3 0.0 0.002 16.9 0.0 1.1 1 0 0 1 1 1 1 MCM2/3/5 family G-alpha PF00503.15 KKK20085.1 - 0.011 14.4 0.0 0.013 14.2 0.0 1.1 1 0 0 1 1 1 0 G-protein alpha subunit NACHT PF05729.7 KKK20085.1 - 0.012 15.2 0.0 0.021 14.4 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_21 PF13304.1 KKK20085.1 - 0.017 15.1 0.0 0.023 14.6 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 KKK20085.1 - 0.03 13.8 0.1 0.071 12.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 KKK20085.1 - 0.036 14.3 0.0 0.043 14.1 0.0 1.3 1 0 0 1 1 1 0 ABC transporter AAA_16 PF13191.1 KKK20085.1 - 0.046 13.7 0.0 0.082 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain KAP_NTPase PF07693.9 KKK20085.1 - 0.062 12.2 0.0 0.07 12.1 0.0 1.1 1 0 0 1 1 1 0 KAP family P-loop domain RNA_helicase PF00910.17 KKK20085.1 - 0.062 13.4 0.0 0.29 11.3 0.0 1.9 1 1 0 1 1 1 0 RNA helicase AAA_24 PF13479.1 KKK20085.1 - 0.11 12.1 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 KKK20085.1 - 0.15 12.0 0.0 0.24 11.3 0.0 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase HEM4 PF02602.10 KKK20086.1 - 2.1e-20 72.9 0.0 7.7e-20 71.1 0.0 1.7 1 1 0 1 1 1 1 Uroporphyrinogen-III synthase HemD Pkinase PF00069.20 KKK20087.1 - 2.8e-74 249.5 0.0 3.4e-74 249.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK20087.1 - 3.6e-32 111.4 0.0 4.7e-32 111.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KKK20087.1 - 0.00055 18.9 0.0 0.0015 17.5 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 KKK20087.1 - 0.0022 17.0 0.1 0.0037 16.3 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KKK20087.1 - 0.013 15.1 0.1 0.022 14.5 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 KKK20087.1 - 0.06 12.1 0.0 0.088 11.6 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Sec23_trunk PF04811.10 KKK20088.1 - 3.6e-70 236.1 0.0 7.3e-70 235.0 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 KKK20088.1 - 1.3e-22 79.1 0.0 2.3e-21 75.1 0.0 2.4 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 KKK20088.1 - 6.4e-17 61.8 0.0 1.3e-16 60.8 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 KKK20088.1 - 1.7e-12 46.6 3.0 3.1e-12 45.8 2.1 1.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 KKK20088.1 - 8.1e-09 35.0 0.0 1.9e-08 33.8 0.0 1.7 1 0 0 1 1 1 1 Gelsolin repeat Kinesin PF00225.18 KKK20089.1 - 1.3e-80 270.6 2.8 1.3e-80 270.6 1.9 2.2 2 0 0 2 2 2 1 Kinesin motor domain HHH PF00633.18 KKK20089.1 - 4.5e-07 29.1 0.8 0.022 14.4 0.0 3.2 3 0 0 3 3 3 2 Helix-hairpin-helix motif HHH_5 PF14520.1 KKK20089.1 - 0.0015 18.6 0.2 0.0054 16.8 0.0 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix domain SRA1 PF07304.6 KKK20089.1 - 0.019 14.6 1.9 0.026 14.2 0.4 1.9 2 0 0 2 2 2 0 Steroid receptor RNA activator (SRA1) HHH_3 PF12836.2 KKK20089.1 - 0.033 14.1 1.2 4.1 7.4 0.0 3.2 3 0 0 3 3 3 0 Helix-hairpin-helix motif Ribosomal_S17 PF00366.15 KKK20090.1 - 0.008 16.2 0.4 0.014 15.4 0.3 1.4 1 0 0 1 1 1 1 Ribosomal protein S17 PDDEXK_1 PF12705.2 KKK20090.1 - 0.034 13.5 0.1 4.2 6.6 0.7 2.0 1 1 0 2 2 2 0 PD-(D/E)XK nuclease superfamily DUF2967 PF11179.3 KKK20090.1 - 0.15 11.5 4.9 0.25 10.8 3.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) FGF-BP1 PF06473.7 KKK20090.1 - 0.65 9.5 2.6 0.86 9.1 0.1 1.9 2 0 0 2 2 2 0 FGF binding protein 1 (FGF-BP1) HEAT PF02985.17 KKK20091.1 - 0.00012 21.8 0.1 1.1 9.5 0.1 4.6 4 0 0 4 4 4 1 HEAT repeat IncA PF04156.9 KKK20091.1 - 0.00026 20.6 1.5 0.00026 20.6 1.0 2.0 2 0 0 2 2 2 1 IncA protein CLASP_N PF12348.3 KKK20091.1 - 0.001 18.4 0.4 0.026 13.8 0.2 2.8 2 1 1 3 3 3 1 CLASP N terminal APG6 PF04111.7 KKK20091.1 - 0.0026 16.8 10.2 0.0026 16.8 7.0 2.2 3 0 0 3 3 3 1 Autophagy protein Apg6 TPR_MLP1_2 PF07926.7 KKK20091.1 - 0.0041 16.8 2.3 0.0041 16.8 1.6 2.8 4 0 0 4 4 3 1 TPR/MLP1/MLP2-like protein Adaptin_N PF01602.15 KKK20091.1 - 0.0055 15.0 1.3 0.12 10.6 0.9 2.6 1 1 0 1 1 1 1 Adaptin N terminal region MMS19_N PF14500.1 KKK20091.1 - 0.027 13.7 0.6 0.79 8.9 0.3 2.8 2 1 1 3 3 3 0 Dos2-interacting transcription regulator of RNA-Pol-II FTCD_N PF07837.7 KKK20091.1 - 0.053 13.0 0.5 0.91 9.0 0.0 2.8 3 0 0 3 3 3 0 Formiminotransferase domain, N-terminal subdomain DUF4471 PF14740.1 KKK20091.1 - 0.057 12.6 0.2 0.15 11.2 0.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4471) Cnd1 PF12717.2 KKK20091.1 - 0.088 12.6 0.2 1.6 8.5 0.1 2.5 2 1 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 DUF972 PF06156.8 KKK20091.1 - 1 9.7 4.8 4.2 7.7 3.3 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF972) ADIP PF11559.3 KKK20091.1 - 3.8 7.4 14.9 12 5.7 10.3 1.9 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Tropomyosin PF00261.15 KKK20091.1 - 5.2 6.0 18.6 0.19 10.8 8.6 1.7 2 0 0 2 2 2 0 Tropomyosin Spc7 PF08317.6 KKK20091.1 - 5.5 5.5 11.6 0.61 8.6 4.8 1.7 2 0 0 2 2 2 0 Spc7 kinetochore protein OmpH PF03938.9 KKK20091.1 - 7.9 6.3 14.5 25 4.7 6.4 2.8 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) WD40 PF00400.27 KKK20092.1 - 2.9e-56 185.4 17.3 1.6e-09 37.2 0.3 8.6 8 0 0 8 8 8 7 WD domain, G-beta repeat F-box-like PF12937.2 KKK20092.1 - 9.5e-09 34.8 0.1 2.1e-08 33.7 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KKK20092.1 - 1.3e-07 31.1 0.3 3.5e-07 29.7 0.0 1.9 2 0 0 2 2 2 1 F-box domain Nup160 PF11715.3 KKK20092.1 - 0.00094 17.4 7.8 0.26 9.3 0.1 4.9 2 2 2 5 5 5 3 Nucleoporin Nup120/160 CPSF_A PF03178.10 KKK20092.1 - 0.057 12.5 0.0 0.25 10.3 0.0 2.0 3 0 0 3 3 3 0 CPSF A subunit region Clat_adaptor_s PF01217.15 KKK20094.1 - 2.6e-42 143.9 1.1 7.8e-42 142.3 0.0 2.3 3 1 0 3 3 3 1 Clathrin adaptor complex small chain Ribosomal_L7Ae PF01248.21 KKK20094.1 - 6.9e-23 79.9 0.9 1.2e-22 79.1 0.6 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family MMR_HSR1 PF01926.18 KKK20095.1 - 1.3e-19 70.2 0.0 1.9e-19 69.7 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 KKK20095.1 - 1.2e-05 25.1 0.0 0.0002 21.2 0.0 2.2 1 1 0 2 2 2 1 Dynamin family FeoB_N PF02421.13 KKK20095.1 - 0.00093 18.5 0.0 0.0014 17.9 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 KKK20095.1 - 0.0011 18.4 0.0 0.01 15.2 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 KKK20095.1 - 0.0036 16.4 0.0 0.0064 15.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 KKK20095.1 - 0.0067 15.5 0.0 0.01 14.9 0.0 1.3 1 0 0 1 1 1 1 AIG1 family AAA_33 PF13671.1 KKK20095.1 - 0.011 15.6 0.0 0.019 14.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 KKK20095.1 - 0.016 14.7 0.0 0.035 13.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 KKK20095.1 - 0.022 15.0 0.1 0.036 14.3 0.0 1.5 1 1 0 1 1 1 0 ABC transporter SRPRB PF09439.5 KKK20095.1 - 0.041 13.1 0.0 0.056 12.6 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Miro PF08477.8 KKK20095.1 - 0.12 12.9 0.0 0.21 12.0 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein Nuc_sug_transp PF04142.10 KKK20096.1 - 1.3e-65 220.8 5.2 1.8e-65 220.4 3.6 1.1 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.15 KKK20096.1 - 2.4e-06 27.6 24.0 4.3e-05 23.5 5.4 2.6 2 0 0 2 2 2 2 EamA-like transporter family EmrE PF13536.1 KKK20096.1 - 1.9e-05 24.8 18.4 3.5e-05 23.9 2.5 2.6 2 0 0 2 2 2 2 Multidrug resistance efflux transporter UAA PF08449.6 KKK20096.1 - 0.0012 17.8 6.0 0.0035 16.3 4.2 1.6 1 1 0 1 1 1 1 UAA transporter family TPT PF03151.11 KKK20096.1 - 0.088 12.4 20.2 0.048 13.3 2.8 2.4 2 0 0 2 2 2 0 Triose-phosphate Transporter family UPF0546 PF10639.4 KKK20096.1 - 1.3 8.8 8.4 0.53 10.1 0.6 2.8 2 1 1 3 3 3 0 Uncharacterised protein family UPF0546 2TM PF13239.1 KKK20096.1 - 7.9 6.6 7.6 9.9 6.3 0.3 2.8 2 1 0 2 2 2 0 2TM domain DEAD PF00270.24 KKK20097.1 - 1.3e-28 99.5 0.0 2.6e-28 98.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Sec63 PF02889.11 KKK20097.1 - 3.9e-25 88.7 0.0 1.2e-11 44.4 0.0 2.3 1 1 1 2 2 2 2 Sec63 Brl domain ResIII PF04851.10 KKK20097.1 - 8.8e-11 41.9 0.0 1.7e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 KKK20097.1 - 1.6e-07 31.0 0.0 8.9e-07 28.6 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 KKK20097.1 - 0.00012 22.2 0.1 0.00042 20.4 0.1 1.9 1 1 0 1 1 1 1 AAA domain SNF2_N PF00176.18 KKK20097.1 - 0.00018 20.4 0.1 0.00038 19.3 0.1 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain AAA_19 PF13245.1 KKK20097.1 - 0.016 14.9 0.0 0.037 13.7 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain Helicase_RecD PF05127.9 KKK20097.1 - 0.018 14.6 0.0 0.052 13.1 0.0 1.8 2 0 0 2 2 2 0 Helicase T2SE PF00437.15 KKK20097.1 - 0.026 13.4 0.0 0.058 12.2 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_30 PF13604.1 KKK20097.1 - 0.041 13.4 0.0 0.074 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain SecA_DEAD PF07517.9 KKK20097.1 - 0.045 13.0 0.0 0.094 11.9 0.0 1.4 1 0 0 1 1 1 0 SecA DEAD-like domain UvrD-helicase PF00580.16 KKK20097.1 - 0.079 12.2 0.0 0.16 11.2 0.0 1.4 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain HHH_5 PF14520.1 KKK20097.1 - 0.09 12.9 0.0 0.46 10.6 0.0 2.2 2 0 0 2 2 2 0 Helix-hairpin-helix domain HORMA PF02301.13 KKK20098.1 - 8.5e-51 172.3 0.0 1.4e-50 171.6 0.0 1.3 1 0 0 1 1 1 1 HORMA domain PHD PF00628.24 KKK20098.1 - 0.0056 16.3 7.4 0.011 15.3 5.1 1.5 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 KKK20098.1 - 0.29 10.4 6.4 0.82 9.0 4.5 1.8 1 1 0 1 1 1 0 PHD-finger LRR_4 PF12799.2 KKK20100.1 - 1.5e-07 30.8 4.6 0.00014 21.3 0.2 3.4 4 0 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 KKK20100.1 - 5.5e-06 25.9 1.6 0.87 9.8 0.0 4.4 4 0 0 4 4 4 2 Leucine Rich repeat LRR_1 PF00560.28 KKK20100.1 - 1.2e-05 24.6 0.9 3.1 8.1 0.0 4.5 4 0 0 4 4 4 2 Leucine Rich Repeat LRR_8 PF13855.1 KKK20100.1 - 4.5e-05 23.1 4.0 0.002 17.8 1.5 3.4 2 1 1 3 3 3 1 Leucine rich repeat LRR_7 PF13504.1 KKK20100.1 - 0.0002 21.0 0.2 9 7.0 0.0 4.1 3 0 0 3 3 3 2 Leucine rich repeat Acid_PPase PF12689.2 KKK20101.1 - 8.2e-70 233.8 0.0 9.6e-70 233.5 0.0 1.0 1 0 0 1 1 1 1 Acid Phosphatase HAD_2 PF13419.1 KKK20101.1 - 0.038 14.2 1.1 0.57 10.3 0.1 2.7 1 1 1 2 2 2 0 Haloacid dehalogenase-like hydrolase Aconitase PF00330.15 KKK20102.1 - 3.8e-174 579.5 0.0 9.4e-174 578.2 0.0 1.6 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 KKK20102.1 - 1.9e-45 154.1 0.0 3.5e-45 153.3 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain Mito_carr PF00153.22 KKK20103.1 - 2.6e-50 168.1 0.7 5.2e-22 77.3 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Glyco_transf_20 PF00982.16 KKK20104.1 - 1.2e-199 663.6 0.0 1.4e-199 663.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glyco_transf_5 PF08323.6 KKK20104.1 - 0.0054 16.2 0.3 0.019 14.4 0.1 1.9 2 1 0 2 2 2 1 Starch synthase catalytic domain Lactamase_B PF00753.22 KKK20105.1 - 9.6e-23 80.8 4.0 1.4e-22 80.3 2.6 1.3 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KKK20105.1 - 5.2e-05 22.8 2.2 6.9e-05 22.4 1.5 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 KKK20105.1 - 0.0078 15.9 0.6 0.027 14.2 0.4 1.9 1 1 0 1 1 1 1 Beta-lactamase superfamily domain ABC_tran PF00005.22 KKK20107.1 - 4.8e-35 120.8 0.0 9.8e-35 119.8 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 KKK20107.1 - 1.2e-34 119.9 11.4 1.7e-34 119.5 7.9 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_21 PF13304.1 KKK20107.1 - 6.1e-07 29.6 0.0 0.013 15.5 0.0 2.5 2 1 1 3 3 3 2 AAA domain SMC_N PF02463.14 KKK20107.1 - 8.4e-05 21.9 0.2 0.073 12.2 0.0 2.5 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.4 KKK20107.1 - 9.2e-05 21.2 0.0 0.0014 17.3 0.0 2.1 2 0 0 2 2 2 1 Predicted ATPase of the ABC class AAA_16 PF13191.1 KKK20107.1 - 0.00034 20.6 0.1 0.0011 19.0 0.0 1.9 2 1 0 2 2 1 1 AAA ATPase domain AAA_22 PF13401.1 KKK20107.1 - 0.00038 20.5 0.5 0.0021 18.1 0.0 2.4 2 1 0 2 2 1 1 AAA domain AAA_17 PF13207.1 KKK20107.1 - 0.00039 21.2 0.0 0.0012 19.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KKK20107.1 - 0.00086 19.2 0.0 0.014 15.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain ATP-synt_ab PF00006.20 KKK20107.1 - 0.0016 17.9 0.0 0.0033 16.9 0.0 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_25 PF13481.1 KKK20107.1 - 0.0023 17.3 0.0 0.013 14.9 0.0 2.2 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 KKK20107.1 - 0.003 16.7 0.0 0.0061 15.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 KKK20107.1 - 0.0037 16.7 0.1 0.01 15.3 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_28 PF13521.1 KKK20107.1 - 0.0081 16.1 0.0 0.051 13.5 0.0 2.2 1 1 1 2 2 2 1 AAA domain AAA PF00004.24 KKK20107.1 - 0.0093 16.1 0.0 0.094 12.9 0.0 2.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 KKK20107.1 - 0.0098 15.7 0.2 0.63 9.9 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_10 PF12846.2 KKK20107.1 - 0.011 15.2 0.1 0.048 13.0 0.0 2.0 1 1 1 2 2 2 0 AAA-like domain AAA_23 PF13476.1 KKK20107.1 - 0.019 15.3 0.4 0.05 13.9 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_18 PF13238.1 KKK20107.1 - 0.029 14.6 0.0 0.094 13.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.10 KKK20107.1 - 0.063 11.9 0.0 0.11 11.1 0.0 1.3 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein GPAT_N PF14829.1 KKK20107.1 - 0.066 12.9 0.0 6.5 6.5 0.0 3.1 3 0 0 3 3 3 0 Glycerol-3-phosphate acyltransferase N-terminal Zeta_toxin PF06414.7 KKK20107.1 - 0.066 12.3 0.3 0.49 9.4 0.0 2.6 3 0 0 3 3 3 0 Zeta toxin SbcCD_C PF13558.1 KKK20107.1 - 0.081 12.8 1.9 0.34 10.8 0.2 2.7 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit SNF2_N PF00176.18 KKK20108.1 - 5e-65 219.2 0.0 6.9e-65 218.7 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Rad54_N PF08658.5 KKK20108.1 - 8.3e-64 214.9 3.8 1.3e-62 211.0 2.1 2.4 2 0 0 2 2 2 1 Rad54 N terminal Helicase_C PF00271.26 KKK20108.1 - 3.9e-12 45.8 0.0 1.2e-11 44.3 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 KKK20108.1 - 6.9e-05 21.7 0.0 0.00025 19.9 0.0 1.9 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.10 KKK20108.1 - 0.0081 16.0 0.0 0.059 13.1 0.0 2.3 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Vac14_Fig4_bd PF11916.3 KKK20109.1 - 4.1e-83 276.9 7.9 4.1e-83 276.9 5.5 1.8 2 0 0 2 2 2 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.2 KKK20109.1 - 3.4e-45 152.3 0.0 1.2e-42 144.1 0.0 4.0 4 1 1 5 5 5 1 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 KKK20109.1 - 9.5e-09 35.4 1.3 0.0014 19.0 0.0 4.9 4 1 1 5 5 5 2 HEAT-like repeat HEAT PF02985.17 KKK20109.1 - 2.3e-08 33.4 2.0 0.00022 21.0 0.0 5.4 6 0 0 6 6 6 1 HEAT repeat HEAT_2 PF13646.1 KKK20109.1 - 2.2e-07 31.0 0.8 0.008 16.4 0.0 5.0 4 2 2 6 6 6 2 HEAT repeats Arm PF00514.18 KKK20109.1 - 0.037 13.8 0.0 13 5.7 0.0 4.2 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat Ipi1_N PF12333.3 KKK20109.1 - 0.058 13.3 0.0 2.3 8.2 0.0 3.5 4 0 0 4 4 4 0 Rix1 complex component involved in 60S ribosome maturation IBN_N PF03810.14 KKK20109.1 - 0.063 13.1 0.2 0.36 10.7 0.0 2.5 2 1 0 2 2 2 0 Importin-beta N-terminal domain AIM24 PF01987.12 KKK20110.1 - 2.5e-39 134.9 0.0 3.4e-39 134.5 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 MFS_1 PF07690.11 KKK20111.1 - 2.2e-25 89.1 51.6 2.9e-23 82.1 25.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KKK20111.1 - 3.6e-05 22.5 3.0 3.6e-05 22.5 2.1 2.9 1 1 2 3 3 3 2 Sugar (and other) transporter APH PF01636.18 KKK20120.1 - 0.099 12.3 0.1 2.5 7.7 0.1 2.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family Fungal_trans PF04082.13 KKK20121.1 - 1.2e-23 83.3 2.7 2e-22 79.3 0.0 2.8 3 0 0 3 3 3 2 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK20121.1 - 0.13 12.2 6.8 0.22 11.4 4.7 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Cu-oxidase_3 PF07732.10 KKK20122.1 - 1.9e-34 117.8 0.0 6.6e-34 116.1 0.0 2.0 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 KKK20122.1 - 1.4e-29 102.3 4.0 7.3e-23 80.6 0.7 3.8 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 KKK20122.1 - 5.6e-16 58.8 0.0 2.9e-15 56.5 0.0 2.2 1 1 0 1 1 1 1 Multicopper oxidase Utp14 PF04615.8 KKK20125.1 - 0.44 8.6 19.2 0.5 8.4 13.3 1.0 1 0 0 1 1 1 0 Utp14 protein FAM196 PF15265.1 KKK20125.1 - 3.8 6.6 32.2 4.7 6.3 22.3 1.1 1 0 0 1 1 1 0 FAM196 family DUF605 PF04652.11 KKK20125.1 - 6.8 5.9 30.6 9.2 5.5 21.2 1.2 1 0 0 1 1 1 0 Vta1 like NAD_binding_5 PF07994.7 KKK20126.1 - 2.8e-111 371.7 0.2 3.3e-111 371.4 0.1 1.1 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.12 KKK20126.1 - 3.9e-46 155.4 0.3 7e-46 154.6 0.2 1.4 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase DUF1459 PF07312.6 KKK20126.1 - 0.059 13.2 0.5 0.35 10.7 0.3 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1459) DHHA2 PF02833.9 KKK20126.1 - 0.11 12.7 0.0 0.26 11.4 0.0 1.6 1 0 0 1 1 1 0 DHHA2 domain LIM PF00412.17 KKK20127.1 - 2.7e-18 65.7 16.9 1.9e-11 43.8 1.8 2.8 3 1 0 3 3 3 2 LIM domain Cytochrom_c3_2 PF14537.1 KKK20127.1 - 1.3 9.3 6.9 4.5 7.6 4.8 2.0 1 1 0 1 1 1 0 Cytochrome c3 Cytochrome_C7 PF14522.1 KKK20127.1 - 6 6.5 11.6 1.3 8.7 4.6 2.2 1 1 1 2 2 2 0 Cytochrome c7 ADH_N PF08240.7 KKK20128.1 - 4.7e-27 93.8 1.1 1e-26 92.8 0.7 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KKK20128.1 - 3.6e-18 65.3 0.4 6.6e-18 64.5 0.3 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DapB_N PF01113.15 KKK20128.1 - 0.051 13.4 0.7 0.097 12.5 0.5 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Arf PF00025.16 KKK20129.1 - 1.7e-25 89.2 0.0 3.9e-25 88.0 0.0 1.7 1 1 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 KKK20129.1 - 0.00012 21.4 0.0 0.00019 20.8 0.0 1.3 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 KKK20129.1 - 0.0026 16.9 0.0 0.0052 16.0 0.0 1.5 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 KKK20129.1 - 0.011 16.1 0.0 0.023 15.1 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein G-alpha PF00503.15 KKK20129.1 - 0.03 13.0 2.5 0.3 9.7 1.8 2.7 1 1 0 1 1 1 0 G-protein alpha subunit AAA_29 PF13555.1 KKK20129.1 - 0.1 12.1 0.1 0.24 10.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain RhoGAP PF00620.22 KKK20130.1 - 1.3e-38 131.9 0.0 2.1e-38 131.2 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain Allexi_40kDa PF05549.6 KKK20131.1 - 0.0027 17.0 6.0 0.046 13.0 0.7 2.4 2 0 0 2 2 2 2 Allexivirus 40kDa protein Surfac_D-trimer PF09006.6 KKK20131.1 - 0.046 13.4 1.6 2.4 7.9 0.2 2.8 2 0 0 2 2 2 0 Lung surfactant protein D coiled-coil trimerisation PIG-F PF06699.6 KKK20132.1 - 5.7e-53 179.6 0.0 1.1e-52 178.7 0.0 1.4 1 1 0 1 1 1 1 GPI biosynthesis protein family Pig-F UQ_con PF00179.21 KKK20133.1 - 2.2e-41 140.5 0.0 2.4e-41 140.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KKK20133.1 - 0.00049 19.8 0.0 0.00065 19.4 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 KKK20133.1 - 0.063 13.1 0.8 0.08 12.8 0.6 1.5 1 1 0 1 1 1 0 RWD domain Copper-fist PF00649.13 KKK20134.1 - 9.1e-16 56.7 4.9 1.6e-15 55.9 3.4 1.4 1 0 0 1 1 1 1 Copper fist DNA binding domain HhH-GPD PF00730.20 KKK20135.1 - 1.7e-19 70.1 0.0 6.3e-19 68.2 0.0 1.9 2 1 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 KKK20135.1 - 2.1e-06 27.0 0.0 4.9e-06 25.9 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif AAA_11 PF13086.1 KKK20137.1 - 3e-62 210.2 0.6 6.3e-62 209.2 0.2 1.7 2 0 0 2 2 1 1 AAA domain AAA_12 PF13087.1 KKK20137.1 - 1.4e-57 194.3 0.0 2.4e-57 193.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 KKK20137.1 - 7.5e-13 48.4 0.0 5.3e-11 42.4 0.0 2.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KKK20137.1 - 1.4e-12 47.1 0.1 5.2e-12 45.3 0.0 2.0 2 0 0 2 2 1 1 Part of AAA domain Viral_helicase1 PF01443.13 KKK20137.1 - 2.2e-07 30.6 0.0 0.045 13.2 0.0 3.3 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase ResIII PF04851.10 KKK20137.1 - 2.2e-07 30.8 0.0 4.2e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2075 PF09848.4 KKK20137.1 - 4.1e-06 26.0 0.2 2.1e-05 23.6 0.1 2.1 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) DEAD PF00270.24 KKK20137.1 - 7.6e-05 22.2 0.1 0.00091 18.7 0.1 2.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_RecD PF05127.9 KKK20137.1 - 7.9e-05 22.3 0.0 0.17 11.5 0.0 2.9 2 1 0 3 3 3 2 Helicase AAA_22 PF13401.1 KKK20137.1 - 0.00021 21.4 0.1 0.015 15.4 0.1 2.5 1 1 0 1 1 1 1 AAA domain UvrD-helicase PF00580.16 KKK20137.1 - 0.00032 20.0 0.3 0.0024 17.2 0.1 2.2 1 1 1 2 2 2 1 UvrD/REP helicase N-terminal domain PhoH PF02562.11 KKK20137.1 - 0.00039 19.7 0.0 0.012 14.9 0.0 2.5 2 0 0 2 2 2 1 PhoH-like protein UvrD_C PF13361.1 KKK20137.1 - 0.0006 19.3 0.0 0.65 9.4 0.0 2.9 2 1 1 3 3 3 2 UvrD-like helicase C-terminal domain Flavi_DEAD PF07652.9 KKK20137.1 - 0.0015 18.2 0.1 0.011 15.4 0.1 2.3 2 0 0 2 2 2 1 Flavivirus DEAD domain T2SE PF00437.15 KKK20137.1 - 0.0017 17.2 0.0 0.003 16.5 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein IstB_IS21 PF01695.12 KKK20137.1 - 0.003 17.0 0.0 0.01 15.2 0.0 1.8 2 0 0 2 2 2 1 IstB-like ATP binding protein CbiA PF01656.18 KKK20137.1 - 0.003 16.9 0.1 0.017 14.5 0.1 2.3 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_16 PF13191.1 KKK20137.1 - 0.0053 16.7 0.8 0.015 15.3 0.1 2.2 2 1 0 2 2 1 1 AAA ATPase domain AAA PF00004.24 KKK20137.1 - 0.0062 16.7 0.0 0.034 14.3 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 KKK20137.1 - 0.0078 15.6 0.0 0.049 13.0 0.0 2.2 1 1 0 2 2 2 1 AAA domain Zot PF05707.7 KKK20137.1 - 0.0087 15.5 0.0 0.024 14.1 0.0 1.8 2 0 0 2 2 2 1 Zonular occludens toxin (Zot) 4HB_MCP_1 PF12729.2 KKK20137.1 - 0.015 14.6 0.1 0.031 13.6 0.1 1.4 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction UvrD_C_2 PF13538.1 KKK20137.1 - 0.018 15.1 0.1 4.1 7.6 0.0 3.0 2 1 1 3 3 3 0 UvrD-like helicase C-terminal domain TrwB_AAD_bind PF10412.4 KKK20137.1 - 0.025 13.1 0.0 0.05 12.2 0.0 1.4 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_5 PF07728.9 KKK20137.1 - 0.034 13.8 0.1 0.56 9.9 0.0 2.8 2 1 1 3 3 3 0 AAA domain (dynein-related subfamily) AAA_10 PF12846.2 KKK20137.1 - 0.035 13.5 0.0 1.3 8.3 0.0 2.3 1 1 1 2 2 2 0 AAA-like domain AAA_17 PF13207.1 KKK20137.1 - 0.076 13.8 0.6 0.34 11.7 0.4 2.3 1 1 0 1 1 1 0 AAA domain PIF1 PF05970.9 KKK20137.1 - 0.099 11.5 0.0 3.7 6.3 0.0 2.4 2 1 0 2 2 2 0 PIF1-like helicase Glyco_hydro_72 PF03198.9 KKK20138.1 - 8e-137 455.4 5.0 9.5e-137 455.1 3.4 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.13 KKK20138.1 - 2.4e-06 26.9 0.1 2.2e-05 23.8 0.1 2.2 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) PBP PF01161.15 KKK20139.1 - 1.8e-23 82.9 0.0 2.4e-23 82.6 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein zf-Tim10_DDP PF02953.10 KKK20140.1 - 1.4e-20 72.3 3.9 1.8e-20 71.9 2.7 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger RNA_lig_T4_1 PF09511.5 KKK20140.1 - 0.019 14.4 0.2 0.021 14.3 0.2 1.1 1 0 0 1 1 1 0 RNA ligase DUF842 PF05811.8 KKK20140.1 - 0.028 13.8 2.9 0.05 13.0 1.9 1.5 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) DUF1546 PF07571.8 KKK20140.1 - 0.034 14.2 0.0 0.044 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1546) Peptidase_M16_C PF05193.16 KKK20154.1 - 1.5e-51 174.7 0.0 9.4e-51 172.1 0.0 2.2 2 0 0 2 2 2 1 Peptidase M16 inactive domain AMP-binding PF00501.23 KKK20154.1 - 1e-41 142.7 0.0 1.8e-41 141.9 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Peptidase_M16 PF00675.15 KKK20154.1 - 2.7e-41 140.7 0.0 3.5e-40 137.1 0.0 2.2 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) AMP-binding_C PF13193.1 KKK20154.1 - 6.8e-05 23.7 0.0 0.00025 21.9 0.0 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain DUF4211 PF13926.1 KKK20155.1 - 9e-43 145.3 0.0 2.1e-42 144.1 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4211) Toxin_14 PF07829.6 KKK20155.1 - 0.33 10.7 5.1 0.7 9.6 3.5 1.5 1 0 0 1 1 1 0 Alpha-A conotoxin PIVA-like protein Tom22 PF04281.8 KKK20156.1 - 1.8e-53 179.7 1.3 2e-53 179.5 0.9 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 HLH PF00010.21 KKK20157.1 - 2.2e-14 52.8 0.5 5.3e-14 51.6 0.4 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Sugar_tr PF00083.19 KKK20158.1 - 2.8e-96 322.8 24.4 3.2e-96 322.6 16.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KKK20158.1 - 9.2e-30 103.5 30.1 9.7e-22 77.1 3.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KKK20158.1 - 0.0072 14.7 29.0 0.0078 14.6 4.5 3.7 3 1 1 4 4 4 2 MFS/sugar transport protein IBR PF01485.16 KKK20163.1 - 5.6e-23 80.5 47.3 4.3e-12 45.7 6.1 4.5 3 1 1 4 4 4 3 IBR domain zf-C3HC4_2 PF13923.1 KKK20163.1 - 5.5e-06 26.3 7.1 5.5e-06 26.3 5.0 4.5 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KKK20163.1 - 3.7e-05 23.4 5.2 3.7e-05 23.4 3.6 3.5 2 1 1 3 3 3 2 Ring finger domain zf-C3HC4 PF00097.20 KKK20163.1 - 0.00012 21.6 5.1 0.00012 21.6 3.6 4.5 3 1 1 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KKK20163.1 - 0.0029 17.2 8.4 0.0029 17.2 5.8 3.6 3 0 0 3 3 3 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 KKK20163.1 - 0.0033 17.0 1.9 0.0033 17.0 1.3 3.6 3 0 0 3 3 3 1 RING-type zinc-finger UN_NPL4 PF11543.3 KKK20163.1 - 0.013 15.7 0.0 0.027 14.7 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 AceK PF06315.6 KKK20163.1 - 0.045 12.0 0.2 0.064 11.5 0.2 1.1 1 0 0 1 1 1 0 Isocitrate dehydrogenase kinase/phosphatase (AceK) APH PF01636.18 KKK20164.1 - 3.5e-10 40.0 0.0 1.4e-09 38.0 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.20 KKK20170.1 - 5.3e-15 55.2 0.0 7.4e-15 54.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK20170.1 - 7.7e-07 28.4 0.0 1.5e-06 27.5 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KKK20170.1 - 0.0018 18.0 0.1 0.003 17.3 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Polyketide_cyc2 PF10604.4 KKK20171.1 - 3.9e-07 30.3 9.4 6.3e-06 26.4 6.5 2.6 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport AHSA1 PF08327.6 KKK20171.1 - 0.00059 19.9 1.5 0.0044 17.1 1.1 2.1 1 1 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein Polyketide_cyc PF03364.15 KKK20171.1 - 0.0028 17.6 2.7 0.0046 16.9 1.8 1.6 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport DUF4232 PF14016.1 KKK20171.1 - 0.17 11.5 3.0 0.23 11.1 1.9 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4232) JAB PF01398.16 KKK20172.1 - 3e-15 55.9 0.0 5e-15 55.2 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease USP8_dimer PF08969.6 KKK20172.1 - 1.6e-09 37.7 0.2 2.8e-09 36.9 0.1 1.3 1 0 0 1 1 1 1 USP8 dimerisation domain Prok-JAB PF14464.1 KKK20172.1 - 1.1e-05 24.9 0.0 3e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain TLD PF07534.11 KKK20173.1 - 1e-07 32.0 0.0 1.7e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 TLD DUF3446 PF11928.3 KKK20173.1 - 0.02 15.0 4.6 0.02 15.0 3.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3446) SR-25 PF10500.4 KKK20173.1 - 5.7 6.3 11.2 0.92 8.9 5.1 1.5 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein RrnaAD PF00398.15 KKK20174.1 - 0.00032 19.8 0.0 0.00054 19.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase ApbA_C PF08546.6 KKK20174.1 - 0.044 13.7 0.0 0.092 12.7 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA C terminal DUF848 PF05852.6 KKK20174.1 - 0.083 12.7 0.3 0.13 12.1 0.2 1.3 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) Prominin PF05478.6 KKK20174.1 - 0.43 8.0 0.7 0.6 7.5 0.5 1.1 1 0 0 1 1 1 0 Prominin Mito_carr PF00153.22 KKK20188.1 - 2.7e-62 206.4 4.6 2.1e-21 75.4 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF4237 PF14021.1 KKK20190.1 - 4.2e-33 113.4 0.1 1.1e-32 112.1 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF4237) RTA1 PF04479.8 KKK20191.1 - 2.8e-45 154.5 2.2 4.1e-45 154.0 1.5 1.1 1 0 0 1 1 1 1 RTA1 like protein UQ_con PF00179.21 KKK20192.1 - 9.5e-44 148.2 0.0 1.1e-43 148.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 KKK20192.1 - 0.25 11.2 1.9 0.57 10.0 1.3 1.8 1 1 0 1 1 1 0 RWD domain NAD_binding_4 PF07993.7 KKK20193.1 - 2e-35 121.8 0.0 2.7e-35 121.5 0.0 1.1 1 0 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.10 KKK20193.1 - 1.7e-06 27.2 0.0 2.4e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.20 KKK20193.1 - 0.016 15.1 0.0 0.027 14.3 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase KR PF08659.5 KKK20193.1 - 0.023 14.3 0.0 0.038 13.6 0.0 1.3 1 0 0 1 1 1 0 KR domain Zn_clus PF00172.13 KKK20194.1 - 3.8e-10 39.4 9.5 7.8e-10 38.4 6.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KKK20194.1 - 9.9e-05 21.0 1.0 0.00015 20.4 0.7 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Peptidase_C14 PF00656.17 KKK20194.1 - 0.0022 17.7 0.0 0.0047 16.6 0.0 1.5 1 0 0 1 1 1 1 Caspase domain Raptor_N PF14538.1 KKK20194.1 - 0.015 15.1 0.0 0.033 14.0 0.0 1.5 1 0 0 1 1 1 0 Raptor N-terminal CASPase like domain Glyco_trans_1_4 PF13692.1 KKK20195.1 - 7.4e-29 100.6 0.0 1.4e-28 99.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.15 KKK20195.1 - 4.9e-07 29.3 0.0 7.8e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 KKK20195.1 - 5e-06 26.7 0.0 9.1e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 KKK20195.1 - 0.00091 19.3 0.1 0.0022 18.1 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Cation_efflux PF01545.16 KKK20196.1 - 1.1e-52 178.9 11.1 1.1e-52 178.9 7.7 3.2 3 1 0 3 3 3 1 Cation efflux family Zip PF02535.17 KKK20196.1 - 0.048 12.6 42.7 0.17 10.8 17.0 4.5 2 1 1 3 3 3 0 ZIP Zinc transporter ADH_N PF08240.7 KKK20197.1 - 1.2e-06 28.2 0.0 3.2e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KKK20197.1 - 0.0006 19.3 0.1 0.0011 18.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Abhydrolase_3 PF07859.8 KKK20198.1 - 3.1e-49 167.4 0.1 4.6e-49 166.8 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 KKK20198.1 - 2.4e-07 29.8 1.6 5.2e-07 28.7 1.1 1.5 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 KKK20198.1 - 8e-05 22.4 0.0 0.0001 22.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KKK20198.1 - 0.049 12.8 0.2 4.3 6.4 0.1 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family Methyltransf_23 PF13489.1 KKK20199.1 - 0.0026 17.5 0.0 0.0026 17.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 KKK20199.1 - 0.05 12.7 0.0 0.065 12.3 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) TFIIIC_delta PF12657.2 KKK20200.1 - 6.7e-47 159.3 1.3 9.5e-47 158.9 0.5 1.6 2 0 0 2 2 2 1 Transcription factor IIIC subunit delta N-term zf-TFIIIC PF12660.2 KKK20200.1 - 6.8e-31 106.1 1.7 1.3e-30 105.1 1.2 1.5 1 0 0 1 1 1 1 Putative zinc-finger of transcription factor IIIC complex Kinesin PF00225.18 KKK20201.1 - 3e-111 371.3 0.0 6.5e-111 370.2 0.0 1.6 1 0 0 1 1 1 1 Kinesin motor domain UQ_con PF00179.21 KKK20201.1 - 6.3e-49 165.0 0.0 1.4e-48 163.8 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Reo_sigmaC PF04582.7 KKK20201.1 - 0.061 12.4 24.3 0.039 13.1 1.1 4.3 3 1 1 4 4 4 0 Reovirus sigma C capsid protein DinB_2 PF12867.2 KKK20201.1 - 0.36 11.1 0.0 0.36 11.1 0.0 3.0 4 1 0 4 4 4 0 DinB superfamily His_Phos_1 PF00300.17 KKK20202.1 - 1.3e-08 35.0 0.1 3.5e-07 30.4 0.0 2.2 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) p450 PF00067.17 KKK20203.1 - 1.5e-12 46.8 0.1 1.8e-11 43.2 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 PCI PF01399.22 KKK20204.1 - 0.045 14.0 0.0 9.7 6.5 0.0 2.8 3 0 0 3 3 3 0 PCI domain Peptidase_M3_N PF08439.5 KKK20204.1 - 0.14 12.2 0.2 4.4 7.4 0.0 2.4 2 0 0 2 2 2 0 Oligopeptidase F 5_nucleotid_C PF02872.13 KKK20205.1 - 4.7e-36 124.1 0.0 7.9e-36 123.3 0.0 1.3 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.23 KKK20205.1 - 2.8e-08 33.4 0.0 4.7e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase EMP70 PF02990.11 KKK20206.1 - 1.3e-188 627.7 0.6 1.8e-188 627.2 0.4 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 NfeD PF01957.13 KKK20206.1 - 0.075 13.1 0.0 0.075 13.1 0.0 4.1 3 2 1 4 4 4 0 NfeD-like C-terminal, partner-binding Sas10_Utp3 PF04000.10 KKK20207.1 - 3.3e-16 59.2 0.2 6.8e-16 58.2 0.1 1.6 1 0 0 1 1 1 1 Sas10/Utp3/C1D family Fungal_trans_2 PF11951.3 KKK20208.1 - 0.00031 19.4 0.0 0.00051 18.7 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Toprim_Crpt PF13342.1 KKK20208.1 - 0.13 11.9 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 C-terminal repeat of topoisomerase EF-hand_7 PF13499.1 KKK20209.1 - 1.3e-29 102.1 11.0 5e-14 52.1 0.6 3.2 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.27 KKK20209.1 - 2.5e-25 85.7 11.8 5.1e-08 31.6 0.1 4.8 5 0 0 5 5 5 4 EF hand EF-hand_6 PF13405.1 KKK20209.1 - 4.7e-25 85.1 3.2 6.1e-06 25.6 0.0 5.3 4 1 1 5 5 5 4 EF-hand domain EF-hand_5 PF13202.1 KKK20209.1 - 1e-17 62.5 11.5 9.3e-05 21.6 0.0 4.8 5 0 0 5 5 5 4 EF hand EF-hand_8 PF13833.1 KKK20209.1 - 1.9e-15 56.2 13.2 5.1e-06 26.0 1.1 4.2 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.2 KKK20209.1 - 2.4e-10 40.0 6.8 0.0031 17.2 0.1 4.0 1 1 3 4 4 4 3 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 KKK20209.1 - 9.1e-05 22.2 0.5 0.061 13.2 0.0 3.4 2 1 1 3 3 3 1 EF-hand domain EF-hand_10 PF14788.1 KKK20209.1 - 0.00048 19.7 1.7 0.33 10.6 0.0 3.7 4 0 0 4 4 4 1 EF hand SPARC_Ca_bdg PF10591.4 KKK20209.1 - 0.015 15.3 1.3 1.2 9.1 0.1 3.0 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region DUF1679 PF07914.6 KKK20209.1 - 0.027 13.0 0.6 2.3 6.7 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) EF-hand_2 PF09068.6 KKK20209.1 - 0.051 13.6 0.1 5.8 6.9 0.0 3.1 3 1 0 3 3 3 0 EF hand DAG_kinase_N PF14513.1 KKK20209.1 - 0.25 11.5 2.4 0.35 11.0 1.7 1.5 1 1 0 1 1 1 0 Diacylglycerol kinase N-terminus FAD_binding_3 PF01494.14 KKK20210.1 - 7.4e-36 123.9 0.0 8.8e-36 123.6 0.0 1.0 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 KKK20210.1 - 2.9e-05 23.1 0.0 0.066 12.1 0.0 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KKK20210.1 - 0.00018 20.5 0.1 0.018 13.8 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Pyr_redox PF00070.22 KKK20210.1 - 0.0026 18.1 0.0 0.47 10.8 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KKK20210.1 - 0.0034 16.5 0.0 0.0061 15.6 0.0 1.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase Trp_halogenase PF04820.9 KKK20210.1 - 0.014 14.0 0.0 0.014 14.0 0.0 1.1 1 0 0 1 1 1 0 Tryptophan halogenase Thi4 PF01946.12 KKK20210.1 - 0.027 13.5 0.1 0.32 10.0 0.0 2.0 2 0 0 2 2 2 0 Thi4 family NAD_binding_8 PF13450.1 KKK20210.1 - 0.083 12.9 0.0 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Fungal_trans PF04082.13 KKK20211.1 - 6.5e-09 35.0 0.0 1e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK20211.1 - 1.2e-06 28.2 7.1 2.4e-06 27.3 4.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Epimerase PF01370.16 KKK20212.1 - 8.8e-08 31.8 0.1 4.4e-06 26.3 0.0 2.5 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KKK20212.1 - 1.9e-06 28.0 0.0 5.2e-06 26.5 0.0 1.8 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 KKK20212.1 - 3.6e-06 26.3 0.1 2.7e-05 23.5 0.0 2.2 2 1 1 3 3 3 1 NmrA-like family NAD_binding_4 PF07993.7 KKK20212.1 - 0.00023 20.1 0.0 0.00038 19.4 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein adh_short PF00106.20 KKK20212.1 - 0.0045 16.9 0.2 0.016 15.1 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase Semialdhyde_dh PF01118.19 KKK20212.1 - 0.051 13.8 0.0 0.95 9.7 0.0 2.4 1 1 1 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Sugar_tr PF00083.19 KKK20213.1 - 3.9e-88 296.0 22.0 4.8e-88 295.7 15.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KKK20213.1 - 8.4e-16 57.6 27.4 8.4e-16 57.6 19.0 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1700 PF08006.6 KKK20213.1 - 0.027 13.7 2.8 0.59 9.4 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1700) Dioxygenase_C PF00775.16 KKK20214.1 - 5.8e-12 45.2 0.3 9.8e-12 44.5 0.2 1.3 1 0 0 1 1 1 1 Dioxygenase Hemerythrin PF01814.18 KKK20215.1 - 3.2e-12 46.7 0.3 4.3e-12 46.3 0.2 1.3 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain DHquinase_I PF01487.10 KKK20221.1 - 9.8e-53 179.0 0.0 1.4e-52 178.5 0.0 1.3 1 0 0 1 1 1 1 Type I 3-dehydroquinase Shikimate_dh_N PF08501.6 KKK20221.1 - 1.8e-20 72.7 0.0 3.7e-20 71.7 0.0 1.6 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain SKI PF01202.17 KKK20221.1 - 2.7e-20 72.8 0.0 4.9e-20 72.0 0.0 1.4 1 0 0 1 1 1 1 Shikimate kinase Shikimate_DH PF01488.15 KKK20221.1 - 4.2e-11 43.0 0.0 1.1e-10 41.7 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase AAA_17 PF13207.1 KKK20221.1 - 0.00031 21.5 0.0 0.00071 20.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KKK20221.1 - 0.0022 17.8 0.0 0.0048 16.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 KKK20221.1 - 0.0051 16.7 0.0 0.012 15.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain F420_oxidored PF03807.12 KKK20221.1 - 0.13 12.6 0.1 1.5 9.2 0.0 2.4 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent AAA PF00004.24 KKK20221.1 - 0.17 12.0 0.0 0.31 11.2 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Fungal_trans PF04082.13 KKK20222.1 - 4.1e-21 75.0 0.0 7.5e-21 74.1 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK20222.1 - 2.3e-08 33.7 12.9 3.6e-08 33.1 8.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3405 PF11885.3 KKK20224.1 - 3e-223 741.5 0.3 3.5e-223 741.3 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) Sod_Cu PF00080.15 KKK20225.1 - 7.5e-15 55.3 0.0 1.1e-14 54.8 0.0 1.2 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Inositol_P PF00459.20 KKK20226.1 - 3.9e-80 269.0 0.0 4.5e-80 268.8 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family DHquinase_II PF01220.14 KKK20227.1 - 3.7e-62 207.7 0.1 4.3e-62 207.5 0.1 1.0 1 0 0 1 1 1 1 Dehydroquinase class II Sugar_tr PF00083.19 KKK20228.1 - 9.6e-135 449.6 23.3 1.1e-134 449.4 16.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KKK20228.1 - 3e-29 101.8 58.6 3.6e-26 91.7 23.2 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Shikimate_dh_N PF08501.6 KKK20229.1 - 3.3e-24 84.7 0.0 5.4e-24 84.0 0.0 1.4 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 KKK20229.1 - 5.5e-16 58.8 0.0 9e-16 58.1 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase AP_endonuc_2 PF01261.19 KKK20230.1 - 1.8e-25 89.4 0.5 2.6e-25 88.9 0.3 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel CHORD PF04968.7 KKK20231.1 - 2.2e-52 175.1 20.0 4.4e-27 94.1 4.2 2.2 2 0 0 2 2 2 2 CHORD CS PF04969.11 KKK20231.1 - 1.9e-15 57.1 0.1 2.9e-15 56.5 0.1 1.3 1 0 0 1 1 1 1 CS domain Pheromone PF08015.6 KKK20231.1 - 0.017 15.9 0.5 0.04 14.7 0.4 1.6 1 0 0 1 1 1 0 Fungal mating-type pheromone Aminotran_3 PF00202.16 KKK20232.1 - 1.5e-96 323.1 0.0 1.9e-96 322.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 KKK20232.1 - 5.6e-05 22.2 0.0 8.6e-05 21.6 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class I and II Choline_kinase PF01633.15 KKK20233.1 - 3.4e-46 157.4 0.0 7.6e-45 153.0 0.0 2.1 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.18 KKK20233.1 - 1.5e-11 44.4 0.2 4.3e-11 42.9 0.1 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.15 KKK20233.1 - 0.07 12.2 0.0 0.43 9.6 0.0 2.0 1 1 0 1 1 1 0 Ecdysteroid kinase DUF836 PF05768.9 KKK20234.1 - 8.3e-13 48.4 0.0 1e-12 48.1 0.0 1.1 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_2 PF13098.1 KKK20234.1 - 0.043 14.0 0.1 0.051 13.7 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin-like domain Glutaredoxin PF00462.19 KKK20234.1 - 0.062 13.2 0.1 0.091 12.7 0.1 1.3 1 0 0 1 1 1 0 Glutaredoxin DUF1674 PF07896.7 KKK20235.1 - 7.5e-16 58.0 2.8 7.5e-16 58.0 1.9 1.8 2 1 0 2 2 2 1 Protein of unknown function (DUF1674) MARVEL PF01284.18 KKK20237.1 - 0.0012 18.7 15.2 0.003 17.3 10.6 1.6 1 1 0 1 1 1 1 Membrane-associating domain DUF898 PF05987.8 KKK20237.1 - 8.6 5.1 8.4 0.76 8.6 1.8 2.0 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF898) FAD_binding_4 PF01565.18 KKK20238.1 - 4.4e-20 71.5 0.8 7.4e-20 70.8 0.3 1.6 2 0 0 2 2 2 1 FAD binding domain BolA PF01722.13 KKK20239.1 - 2.2e-28 98.0 1.2 2.8e-28 97.7 0.8 1.1 1 0 0 1 1 1 1 BolA-like protein DDE_3 PF13358.1 KKK20239.1 - 0.034 13.9 0.1 0.042 13.6 0.0 1.1 1 0 0 1 1 1 0 DDE superfamily endonuclease RPA_C PF08784.6 KKK20239.1 - 0.061 13.7 0.1 0.081 13.3 0.0 1.3 1 0 0 1 1 1 0 Replication protein A C terminal RNB PF00773.14 KKK20240.1 - 3e-49 168.0 0.0 3e-47 161.5 0.0 2.3 1 1 0 1 1 1 1 RNB domain Glyco_hydro_7 PF00840.15 KKK20241.1 - 1.6e-137 458.4 17.4 1.6e-113 379.3 9.7 2.0 1 1 1 2 2 2 2 Glycosyl hydrolase family 7 Metallothio PF00131.15 KKK20241.1 - 0.81 9.6 15.1 0.16 11.8 0.6 3.2 3 0 0 3 3 3 0 Metallothionein TPR_10 PF13374.1 KKK20242.1 - 1.2e-31 107.6 0.8 3.3e-11 42.7 0.0 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 KKK20242.1 - 9.2e-30 102.4 0.8 7.7e-17 61.0 0.1 3.1 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 KKK20242.1 - 1.3e-07 31.1 0.4 8.2e-06 25.3 0.0 2.2 1 1 1 2 2 2 1 TPR repeat TPR_2 PF07719.12 KKK20242.1 - 3.8e-07 29.5 1.0 0.032 14.1 0.1 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 KKK20242.1 - 9.8e-06 25.3 0.2 1 9.7 0.0 3.7 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 KKK20242.1 - 1.5e-05 24.4 0.2 0.079 12.6 0.0 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 KKK20242.1 - 2.2e-05 23.9 0.2 0.015 15.0 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_4 PF07721.9 KKK20242.1 - 0.0084 16.4 0.0 3.4 8.3 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 KKK20242.1 - 0.018 14.7 0.2 0.66 9.8 0.1 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 KKK20242.1 - 0.084 13.3 0.3 6 7.5 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 KKK20242.1 - 0.15 12.7 0.9 22 6.0 0.0 2.9 2 1 1 3 3 3 0 Tetratricopeptide repeat Fungal_trans_2 PF11951.3 KKK20243.1 - 3.8e-07 29.0 1.0 7e-07 28.1 0.2 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK20243.1 - 2.6e-06 27.2 9.2 5.2e-06 26.2 6.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HEAT_2 PF13646.1 KKK20243.1 - 0.031 14.5 0.0 0.068 13.4 0.0 1.5 1 0 0 1 1 1 0 HEAT repeats MFS_1 PF07690.11 KKK20244.1 - 6.5e-14 51.4 10.7 1.7e-13 50.0 7.4 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily YflT PF11181.3 KKK20244.1 - 0.1 12.7 0.4 0.18 11.9 0.3 1.3 1 0 0 1 1 1 0 Heat induced stress protein YflT SNARE PF05739.14 KKK20245.1 - 4.3e-10 39.1 4.5 1.5e-09 37.3 3.1 2.0 1 0 0 1 1 1 1 SNARE domain Dispanin PF04505.7 KKK20245.1 - 0.02 14.4 0.5 0.042 13.3 0.3 1.5 1 0 0 1 1 1 0 Interferon-induced transmembrane protein MCPsignal PF00015.16 KKK20245.1 - 0.03 13.8 10.4 0.051 13.1 5.3 2.2 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain HisKA_3 PF07730.8 KKK20245.1 - 0.039 14.3 12.3 0.26 11.6 0.0 4.1 4 1 1 5 5 5 0 Histidine kinase DUF2370 PF10176.4 KKK20245.1 - 0.079 12.2 0.0 0.22 10.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) Fusion_gly PF00523.13 KKK20245.1 - 0.13 10.2 2.4 0.12 10.3 0.2 1.9 1 1 1 2 2 2 0 Fusion glycoprotein F0 AAA_13 PF13166.1 KKK20245.1 - 0.21 9.9 7.3 0.35 9.2 5.0 1.4 1 0 0 1 1 1 0 AAA domain Syntaxin_2 PF14523.1 KKK20245.1 - 0.36 10.8 11.2 1.7 8.7 2.4 3.0 2 1 1 3 3 3 0 Syntaxin-like protein Synaptobrevin PF00957.16 KKK20245.1 - 0.48 10.0 3.6 0.2 11.2 0.3 2.1 2 0 0 2 2 2 0 Synaptobrevin CDC37_N PF03234.9 KKK20245.1 - 0.82 9.9 10.4 0.86 9.8 1.7 2.1 2 0 0 2 2 2 0 Cdc37 N terminal kinase binding DUF1664 PF07889.7 KKK20245.1 - 1.1 9.0 5.4 1.4 8.6 0.4 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) DUF2562 PF10814.3 KKK20245.1 - 2.7 7.9 6.5 3.3 7.6 3.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2562) HTH_37 PF13744.1 KKK20245.1 - 3 7.7 6.3 1.6 8.6 0.9 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain DUF848 PF05852.6 KKK20245.1 - 3.4 7.5 10.1 2.9 7.7 2.3 2.2 2 0 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) DUF724 PF05266.9 KKK20245.1 - 5.4 6.6 8.5 3.1 7.3 1.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Mnd1 PF03962.10 KKK20245.1 - 8.9 5.9 18.0 1.1 8.9 2.2 3.0 1 1 1 3 3 3 0 Mnd1 family Baculo_PEP_C PF04513.7 KKK20245.1 - 9.8 5.9 11.9 3.7 7.3 1.1 3.0 2 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus AMP-binding PF00501.23 KKK20246.1 - 3.7e-66 223.2 0.0 4.5e-66 222.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KKK20246.1 - 3.1e-12 47.2 0.0 5.9e-12 46.3 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Cys_Met_Meta_PP PF01053.15 KKK20247.1 - 6.6e-62 208.9 0.0 1.1e-61 208.2 0.0 1.4 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 KKK20247.1 - 0.0068 15.1 0.0 0.013 14.2 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V AurF PF11583.3 KKK20248.1 - 0.085 11.7 0.0 0.094 11.6 0.0 1.0 1 0 0 1 1 1 0 P-aminobenzoate N-oxygenase AurF ThiS PF02597.15 KKK20248.1 - 0.14 12.6 0.0 0.16 12.3 0.0 1.1 1 0 0 1 1 1 0 ThiS family FYVE PF01363.16 KKK20249.1 - 3.7e-21 74.8 1.0 3.7e-21 74.8 0.7 3.5 4 0 0 4 4 4 1 FYVE zinc finger Fungal_trans PF04082.13 KKK20249.1 - 1.9e-05 23.6 0.0 4.1e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK20249.1 - 5e-05 23.1 9.8 5e-05 23.1 6.8 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TRP PF06011.7 KKK20250.1 - 2.9e-95 319.4 23.4 1.3e-94 317.3 16.2 1.8 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 KKK20250.1 - 6.4e-29 100.8 0.1 9.6e-29 100.2 0.1 1.3 1 0 0 1 1 1 1 ML-like domain PNP_UDP_1 PF01048.15 KKK20251.1 - 2.5e-10 39.7 0.8 2.3e-09 36.5 0.5 2.4 1 1 0 1 1 1 1 Phosphorylase superfamily NB-ARC PF00931.17 KKK20251.1 - 7.9e-10 38.0 0.0 1.2e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain NACHT PF05729.7 KKK20251.1 - 2.9e-05 23.8 0.0 5.6e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 KKK20251.1 - 0.00069 19.7 0.0 0.0077 16.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KKK20251.1 - 0.0022 17.9 0.0 0.005 16.8 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.1 KKK20251.1 - 0.061 13.6 0.0 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain CNH PF00780.17 KKK20252.1 - 1.3e-73 247.7 0.0 2.1e-73 247.1 0.0 1.3 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.15 KKK20252.1 - 1.5e-30 106.3 0.8 3.2e-30 105.3 0.5 1.6 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.1 KKK20252.1 - 3.6e-12 46.3 0.0 2.6e-11 43.6 0.0 2.6 1 1 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 KKK20252.1 - 0.00076 19.6 0.0 0.0019 18.3 0.0 1.7 1 0 0 1 1 1 1 PH domain TPP_enzyme_N PF02776.13 KKK20254.1 - 1.6e-34 118.8 0.5 2.8e-34 118.0 0.0 1.7 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain ADH_N PF08240.7 KKK20254.1 - 6.2e-26 90.2 0.4 1.4e-25 89.1 0.3 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KKK20254.1 - 1.6e-22 79.4 0.0 6.3e-22 77.5 0.0 2.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase TPP_enzyme_M PF00205.17 KKK20254.1 - 1.7e-20 73.1 0.0 1e-19 70.6 0.0 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 KKK20254.1 - 5.7e-18 64.9 0.7 2.6e-17 62.8 0.0 2.5 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain adh_short_C2 PF13561.1 KKK20254.1 - 0.11 12.3 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase DUF2284 PF10050.4 KKK20254.1 - 0.13 11.8 0.8 1.6 8.3 0.2 2.3 2 0 0 2 2 2 0 Predicted metal-binding protein (DUF2284) DUF4237 PF14021.1 KKK20255.1 - 1.2e-31 108.8 0.0 1.9e-31 108.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4237) Bgal_small_N PF02929.12 KKK20255.1 - 0.013 14.5 0.0 0.019 13.9 0.0 1.1 1 0 0 1 1 1 0 Beta galactosidase small chain RabGAP-TBC PF00566.13 KKK20256.1 - 4.8e-47 160.2 0.0 9.2e-47 159.2 0.0 1.5 1 0 0 1 1 1 1 Rab-GTPase-TBC domain EF-hand_7 PF13499.1 KKK20256.1 - 0.0083 16.2 0.1 0.067 13.3 0.1 2.6 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 KKK20256.1 - 0.011 15.5 1.2 0.073 12.9 0.1 3.1 4 0 0 4 4 4 0 EF-hand domain GRAM PF02893.15 KKK20256.1 - 0.052 13.0 0.0 0.12 11.9 0.0 1.7 1 0 0 1 1 1 0 GRAM domain adh_short_C2 PF13561.1 KKK20258.1 - 2.4e-18 66.7 0.1 4e-18 66.0 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KKK20258.1 - 2.9e-15 56.5 0.7 5.5e-15 55.6 0.5 1.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KKK20258.1 - 5e-05 23.0 0.1 9.3e-05 22.1 0.1 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KKK20258.1 - 0.11 11.8 0.2 0.22 10.9 0.2 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 KKK20258.1 - 0.12 12.4 0.1 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase EmrE PF13536.1 KKK20259.1 - 0.052 13.7 0.1 0.13 12.5 0.0 1.7 2 1 0 2 2 2 0 Multidrug resistance efflux transporter DUF401 PF04165.7 KKK20259.1 - 0.14 11.1 0.5 0.19 10.7 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF401) MFS_1 PF07690.11 KKK20260.1 - 6e-37 127.1 50.0 8.3e-37 126.6 28.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KKK20260.1 - 1.7e-08 33.4 35.1 1.6e-07 30.3 24.2 2.9 1 1 0 1 1 1 1 Sugar (and other) transporter Glyoxalase_2 PF12681.2 KKK20261.1 - 2.4e-06 28.0 0.0 5e-06 27.0 0.0 1.5 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 KKK20261.1 - 0.023 14.6 0.0 0.046 13.7 0.0 1.5 1 1 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily SUR7 PF06687.7 KKK20262.1 - 8.4e-19 67.9 3.5 1e-18 67.6 2.4 1.1 1 0 0 1 1 1 1 SUR7/PalI family Fig1 PF12351.3 KKK20262.1 - 0.056 13.3 6.3 0.029 14.2 2.7 1.6 2 0 0 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 DUF4282 PF14110.1 KKK20262.1 - 0.088 13.0 0.4 0.088 13.0 0.3 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4282) Claudin_2 PF13903.1 KKK20262.1 - 0.36 10.5 9.2 0.048 13.3 2.1 2.0 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction 2OG-FeII_Oxy_2 PF13532.1 KKK20263.1 - 1.5e-29 103.2 0.0 2.4e-29 102.5 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF1680 PF07944.7 KKK20263.1 - 4.4e-23 81.3 0.0 5.9e-20 71.0 0.0 2.1 2 0 0 2 2 2 2 Putative glycosyl hydrolase of unknown function (DUF1680) Prenyltrans_1 PF13243.1 KKK20263.1 - 0.003 17.5 0.0 0.0077 16.2 0.0 1.6 1 0 0 1 1 1 1 Prenyltransferase-like AhpC-TSA_2 PF13911.1 KKK20264.1 - 1.8e-18 66.5 0.0 2.7e-18 65.9 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.16 KKK20264.1 - 0.0015 18.2 0.0 0.0029 17.2 0.0 1.5 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 KKK20264.1 - 0.024 14.1 0.0 0.045 13.2 0.0 1.4 1 1 0 1 1 1 0 Redoxin Exo_endo_phos PF03372.18 KKK20265.1 - 4.7e-20 72.5 0.1 5.6e-20 72.3 0.1 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family SF3b1 PF08920.5 KKK20272.1 - 2.7e-45 153.9 0.5 2.7e-45 153.9 0.3 2.5 1 1 1 2 2 2 1 Splicing factor 3B subunit 1 HEAT_2 PF13646.1 KKK20272.1 - 5.6e-15 55.3 3.5 0.011 15.9 0.0 7.9 6 3 4 10 10 10 5 HEAT repeats HEAT PF02985.17 KKK20272.1 - 1.2e-09 37.4 11.1 0.15 12.1 0.3 8.9 10 0 0 10 10 10 2 HEAT repeat HEAT_EZ PF13513.1 KKK20272.1 - 4.8e-09 36.4 6.3 0.55 10.8 0.0 7.7 6 2 2 8 8 8 2 HEAT-like repeat Vac14_Fab1_bd PF12755.2 KKK20272.1 - 5.9e-06 26.5 0.6 0.8 10.1 0.0 5.2 4 1 1 5 5 5 2 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.15 KKK20272.1 - 0.00025 19.5 0.5 0.54 8.5 0.0 3.4 2 2 0 3 3 3 1 Adaptin N terminal region CLASP_N PF12348.3 KKK20272.1 - 0.0031 16.8 0.2 1.1 8.6 0.0 3.3 3 0 0 3 3 3 1 CLASP N terminal NUC173 PF08161.7 KKK20272.1 - 0.005 16.2 0.5 2.3 7.5 0.0 3.8 5 0 0 5 5 5 1 NUC173 domain Cnd1 PF12717.2 KKK20272.1 - 0.2 11.4 1.3 28 4.5 0.0 4.3 6 1 0 6 6 6 0 non-SMC mitotic condensation complex subunit 1 B56 PF01603.15 KKK20272.1 - 0.21 10.1 0.0 1.8 7.0 0.0 2.5 3 1 1 4 4 4 0 Protein phosphatase 2A regulatory B subunit (B56 family) Arm PF00514.18 KKK20272.1 - 0.3 10.9 1.4 74 3.3 0.0 4.5 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Sec1 PF00995.18 KKK20273.1 - 1.2e-128 430.2 0.0 1.4e-128 430.0 0.0 1.0 1 0 0 1 1 1 1 Sec1 family SNARE PF05739.14 KKK20274.1 - 0.00084 18.9 3.5 0.00084 18.9 2.4 3.0 3 0 0 3 3 3 1 SNARE domain UQ_con PF00179.21 KKK20275.1 - 8.7e-27 93.2 0.0 1e-26 93.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KKK20275.1 - 1.4e-06 28.1 0.0 1.7e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 KKK20275.1 - 7e-05 22.6 0.2 0.0001 22.1 0.1 1.4 1 1 0 1 1 1 1 RWD domain UEV PF05743.8 KKK20275.1 - 0.056 13.1 0.1 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 UEV domain RNA_pol_A_bac PF01000.21 KKK20276.1 - 9.2e-27 93.4 0.0 1.7e-26 92.5 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 KKK20276.1 - 1.9e-11 42.9 0.0 2.6e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Complex1_49kDa PF00346.14 KKK20277.1 - 1.8e-132 440.4 0.0 2.3e-132 440.0 0.0 1.1 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases PF00374.14 KKK20277.1 - 0.04 12.6 0.0 0.056 12.2 0.0 1.2 1 0 0 1 1 1 0 Nickel-dependent hydrogenase Telomere_reg-2 PF10193.4 KKK20278.1 - 8e-37 126.0 0.0 2.1e-36 124.6 0.0 1.8 1 0 0 1 1 1 1 Telomere length regulation protein TLP-20 PF06088.6 KKK20278.1 - 0.2 11.3 1.6 6.2 6.4 0.0 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Ebola_NP PF05505.7 KKK20278.1 - 0.5 8.3 5.0 0.73 7.8 3.5 1.2 1 0 0 1 1 1 0 Ebola nucleoprotein E2_bind PF08825.5 KKK20279.1 - 4e-30 103.4 0.1 6.1e-30 102.8 0.0 1.3 1 0 0 1 1 1 1 E2 binding domain ThiF PF00899.16 KKK20279.1 - 2.5e-22 79.1 0.2 4.7e-13 49.1 0.0 2.9 2 1 1 3 3 3 2 ThiF family UBACT PF02134.16 KKK20279.1 - 5.3e-22 77.1 1.0 9.9e-22 76.2 0.7 1.5 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 KKK20279.1 - 2.6e-13 49.1 3.3 2.6e-13 49.1 2.3 1.7 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site MoeZ_MoeB PF05237.8 KKK20279.1 - 6.9e-05 22.3 0.0 0.00014 21.3 0.0 1.5 1 0 0 1 1 1 1 MoeZ/MoeB domain Shikimate_DH PF01488.15 KKK20279.1 - 0.0005 20.1 0.2 0.0012 18.9 0.0 1.7 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Baculo_p74_N PF08404.5 KKK20279.1 - 0.1 11.3 0.3 0.18 10.5 0.2 1.3 1 0 0 1 1 1 0 Baculoviridae P74 N-terminal Sugar_tr PF00083.19 KKK20295.1 - 6.5e-24 84.3 25.4 1.9e-17 62.9 4.4 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 KKK20295.1 - 7.1e-16 57.8 32.3 2.1e-08 33.2 12.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily ketoacyl-synt PF00109.21 KKK20296.1 - 5.3e-75 252.1 1.1 1.2e-74 251.0 0.7 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 KKK20296.1 - 6.1e-38 129.3 0.1 1.7e-37 127.8 0.0 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.20 KKK20296.1 - 5.1e-32 109.9 4.4 3.3e-15 56.1 0.5 2.8 2 0 0 2 2 2 2 Phosphopantetheine attachment site PS-DH PF14765.1 KKK20296.1 - 1.3e-26 93.4 0.0 2.7e-26 92.4 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.16 KKK20296.1 - 2.1e-24 86.4 0.0 2.3e-23 83.0 0.0 2.3 2 0 0 2 2 2 1 Acyl transferase domain Methyltransf_12 PF08242.7 KKK20296.1 - 5.4e-19 68.4 0.0 1.6e-18 66.9 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Abhydrolase_3 PF07859.8 KKK20296.1 - 1.9e-15 56.9 0.1 5.4e-12 45.7 0.0 2.6 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KKK20296.1 - 9.3e-13 48.1 0.2 9.7e-10 38.3 0.0 2.8 2 0 0 2 2 2 2 Alpha/beta hydrolase family Methyltransf_31 PF13847.1 KKK20296.1 - 1.5e-11 44.1 0.0 4.6e-11 42.5 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KKK20296.1 - 1.2e-10 41.3 0.0 4.4e-10 39.5 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KKK20296.1 - 1.5e-10 41.4 0.0 6.2e-10 39.4 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain Peptidase_S9 PF00326.16 KKK20296.1 - 2.6e-10 39.8 0.0 4.7e-07 29.2 0.0 2.7 2 0 0 2 2 2 2 Prolyl oligopeptidase family Methyltransf_18 PF12847.2 KKK20296.1 - 2.3e-08 34.6 0.0 2.1e-07 31.4 0.0 2.8 3 0 0 3 3 1 1 Methyltransferase domain Abhydrolase_6 PF12697.2 KKK20296.1 - 5.5e-08 32.9 5.8 1.8e-07 31.2 0.3 3.2 2 1 0 2 2 2 1 Alpha/beta hydrolase family Methyltransf_25 PF13649.1 KKK20296.1 - 9.4e-08 32.3 0.0 3.8e-07 30.3 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain DLH PF01738.13 KKK20296.1 - 3.5e-05 23.1 0.0 0.00057 19.2 0.0 2.4 2 0 0 2 2 2 1 Dienelactone hydrolase family Thiolase_N PF00108.18 KKK20296.1 - 0.00012 21.1 0.1 0.00024 20.1 0.1 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_26 PF13659.1 KKK20296.1 - 0.00021 21.2 0.0 0.00064 19.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_28 PF02636.12 KKK20296.1 - 0.00032 20.1 0.0 0.00062 19.2 0.0 1.4 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Ubie_methyltran PF01209.13 KKK20296.1 - 0.00044 19.4 0.0 0.0011 18.1 0.0 1.6 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Abhydrolase_2 PF02230.11 KKK20296.1 - 0.0021 17.5 0.0 0.38 10.1 0.0 2.6 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Methyltransf_16 PF10294.4 KKK20296.1 - 0.0055 16.1 0.0 0.014 14.8 0.0 1.6 1 0 0 1 1 1 1 Putative methyltransferase LIP PF03583.9 KKK20296.1 - 0.0065 15.6 0.0 0.015 14.5 0.0 1.5 1 0 0 1 1 1 1 Secretory lipase COesterase PF00135.23 KKK20296.1 - 0.014 14.1 0.0 0.024 13.3 0.0 1.3 1 0 0 1 1 1 0 Carboxylesterase family Peptidase_S15 PF02129.13 KKK20296.1 - 0.066 12.6 0.0 0.49 9.7 0.0 2.4 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_1 PF00561.15 KKK20296.1 - 0.074 12.6 2.0 0.17 11.4 0.2 2.4 2 1 0 2 2 2 0 alpha/beta hydrolase fold RrnaAD PF00398.15 KKK20296.1 - 0.14 11.1 0.0 0.31 10.0 0.0 1.5 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Lactamase_B PF00753.22 KKK20297.1 - 3.6e-06 26.7 5.5 2.1e-05 24.2 3.8 2.3 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KKK20297.1 - 0.00031 20.3 0.1 0.00064 19.3 0.1 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 KKK20297.1 - 0.034 13.8 0.0 0.062 13.0 0.0 1.4 1 0 0 1 1 1 0 Beta-lactamase superfamily domain p450 PF00067.17 KKK20298.1 - 3e-55 187.5 0.0 1.3e-54 185.4 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 ketoacyl-synt PF00109.21 KKK20299.1 - 7.2e-66 222.2 0.0 1.8e-65 220.9 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 KKK20299.1 - 5.8e-61 205.3 1.6 1.2e-60 204.3 0.2 2.3 2 0 0 2 2 2 1 KR domain Acyl_transf_1 PF00698.16 KKK20299.1 - 6.6e-56 189.9 0.1 2.3e-55 188.1 0.1 1.9 1 1 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 KKK20299.1 - 6.9e-50 169.8 0.0 2e-49 168.3 0.0 1.8 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 KKK20299.1 - 2.2e-49 167.6 2.5 2.6e-47 160.8 0.1 3.2 2 0 0 2 2 2 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 KKK20299.1 - 2.1e-39 134.0 0.0 6.1e-39 132.5 0.0 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 KKK20299.1 - 7.9e-16 57.7 0.0 4.6e-15 55.3 0.0 2.3 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.1 KKK20299.1 - 3.6e-13 49.5 0.0 1.2e-12 47.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 KKK20299.1 - 4.1e-13 50.3 0.0 7.1e-12 46.3 0.0 3.1 3 0 0 3 3 2 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.7 KKK20299.1 - 1.1e-11 45.0 0.0 1.6e-10 41.3 0.0 3.0 3 0 0 3 3 2 1 Methyltransferase domain PP-binding PF00550.20 KKK20299.1 - 5.5e-06 26.5 0.7 1.4e-05 25.3 0.1 2.0 2 0 0 2 2 1 1 Phosphopantetheine attachment site Methyltransf_31 PF13847.1 KKK20299.1 - 8.3e-06 25.4 0.0 4.1e-05 23.2 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KKK20299.1 - 4.3e-05 22.7 0.0 0.0001 21.4 0.0 1.6 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 KKK20299.1 - 7.8e-05 23.2 0.1 0.0034 17.9 0.0 3.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 KKK20299.1 - 8.6e-05 22.9 0.0 0.0013 19.1 0.0 3.1 3 0 0 3 3 2 1 Methyltransferase domain ADH_N PF08240.7 KKK20299.1 - 0.00014 21.5 0.2 0.00044 19.9 0.1 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_16 PF10294.4 KKK20299.1 - 0.00041 19.8 0.0 0.002 17.5 0.0 2.0 2 0 0 2 2 2 1 Putative methyltransferase Shikimate_DH PF01488.15 KKK20299.1 - 0.029 14.4 0.1 13 5.9 0.0 2.7 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Kinesin-related PF06548.6 KKK20299.1 - 0.14 10.7 0.1 0.21 10.0 0.1 1.2 1 0 0 1 1 1 0 Kinesin-related Transferase PF02458.10 KKK20300.1 - 9.1e-18 63.9 0.0 2.4e-14 52.6 0.0 2.9 3 0 0 3 3 3 3 Transferase family GMC_oxred_N PF00732.14 KKK20301.1 - 1.8e-55 188.2 0.0 2.4e-55 187.7 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KKK20301.1 - 5.2e-33 114.3 0.0 1.3e-32 113.0 0.0 1.7 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_3 PF13738.1 KKK20301.1 - 1.9e-06 28.1 0.1 0.032 14.2 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KKK20301.1 - 3.1e-06 26.3 1.0 5.7e-05 22.1 0.0 2.4 2 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KKK20301.1 - 1e-05 24.5 1.7 0.0057 15.5 0.2 2.2 2 0 0 2 2 2 2 FAD binding domain Trp_halogenase PF04820.9 KKK20301.1 - 1.1e-05 24.3 0.2 1.8e-05 23.5 0.2 1.3 1 0 0 1 1 1 1 Tryptophan halogenase Pyr_redox_2 PF07992.9 KKK20301.1 - 9.8e-05 22.3 0.0 0.0002 21.2 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KKK20301.1 - 0.00035 19.6 0.4 0.0033 16.3 0.1 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 KKK20301.1 - 0.00061 19.7 0.1 0.0018 18.2 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KKK20301.1 - 0.0022 17.1 0.0 0.0079 15.3 0.0 1.8 2 0 0 2 2 2 1 Thi4 family NAD_binding_9 PF13454.1 KKK20301.1 - 0.0076 16.0 0.1 0.018 14.8 0.0 1.6 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox PF00070.22 KKK20301.1 - 0.084 13.2 0.3 0.44 10.9 0.1 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KKK20301.1 - 0.12 10.7 0.1 0.21 10.0 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein GPI-anchored PF10342.4 KKK20302.1 - 1.6e-23 82.9 0.1 1.6e-23 82.9 0.1 2.3 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4448 PF14610.1 KKK20302.1 - 0.023 14.1 0.0 0.035 13.5 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4448) Phosphoesterase PF04185.9 KKK20303.1 - 1.4e-18 67.2 7.3 2.7e-17 63.0 0.7 2.9 2 1 1 3 3 3 3 Phosphoesterase family AA_permease_2 PF13520.1 KKK20304.1 - 9.2e-45 152.9 34.6 6.8e-25 87.4 6.5 2.1 1 1 1 2 2 2 2 Amino acid permease AA_permease PF00324.16 KKK20304.1 - 1.2e-14 53.5 38.8 1.8e-10 39.7 12.0 2.7 1 1 1 2 2 2 2 Amino acid permease MerC PF03203.9 KKK20304.1 - 2.5 8.5 17.2 0.51 10.7 0.5 3.8 3 2 1 4 4 4 0 MerC mercury resistance protein DUF914 PF06027.7 KKK20305.1 - 6.6e-100 334.2 18.3 8.3e-100 333.8 12.7 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF914) EamA PF00892.15 KKK20305.1 - 0.00016 21.7 37.2 0.0041 17.1 10.1 2.8 2 1 1 3 3 3 2 EamA-like transporter family p450 PF00067.17 KKK20306.1 - 2.2e-45 155.0 0.0 3.1e-45 154.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 GRDB PF07355.7 KKK20306.1 - 0.019 13.8 0.0 0.034 13.0 0.0 1.3 1 0 0 1 1 1 0 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) Methyltransf_2 PF00891.13 KKK20307.1 - 1.2e-32 113.0 0.0 4.2e-32 111.2 0.0 1.9 2 0 0 2 2 2 1 O-methyltransferase Fungal_trans PF04082.13 KKK20308.1 - 4.1e-13 48.7 0.1 7.4e-13 47.9 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK20308.1 - 4.5e-09 36.0 11.2 8.6e-09 35.1 7.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Myb_DNA-bind_6 PF13921.1 KKK20309.1 - 3.3e-29 100.7 8.9 1.4e-12 47.5 0.1 3.3 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 KKK20309.1 - 1.6e-28 98.4 15.5 7.5e-12 45.1 1.4 3.5 3 1 0 3 3 3 3 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.4 KKK20309.1 - 0.29 11.3 8.6 9.2 6.5 0.0 3.3 3 0 0 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Rap1_C PF11626.3 KKK20309.1 - 3.2 7.7 6.2 1.7e+02 2.1 4.3 3.1 1 1 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-binding PF00249.26 KKK20310.1 - 1.1e-29 102.1 10.9 6.6e-10 38.8 0.3 3.4 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KKK20310.1 - 9.6e-26 89.6 6.8 1.1e-07 31.8 0.1 3.4 3 0 0 3 3 3 3 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.4 KKK20310.1 - 0.11 12.7 0.9 2.7 8.2 0.1 2.9 3 0 0 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_5 PF13873.1 KKK20310.1 - 0.14 12.1 1.7 24 4.9 0.6 4.0 4 1 0 4 4 4 0 Myb/SANT-like DNA-binding domain MFS_1 PF07690.11 KKK20311.1 - 3.9e-41 140.9 41.9 3.9e-41 140.9 29.0 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KKK20311.1 - 1.7e-14 52.9 14.0 3e-14 52.1 5.5 2.0 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) SYF2 PF08231.7 KKK20347.1 - 1.5e-54 184.3 14.6 1.5e-54 184.3 10.1 2.0 2 0 0 2 2 2 1 SYF2 splicing factor Polysacc_deac_1 PF01522.16 KKK20348.1 - 5.9e-20 71.1 0.0 1.1e-19 70.2 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase Nitroreductase PF00881.19 KKK20348.1 - 2e-14 53.7 0.0 2.9e-14 53.2 0.0 1.3 1 0 0 1 1 1 1 Nitroreductase family Glyco_hydro_57 PF03065.10 KKK20348.1 - 4.8e-07 29.0 0.0 9.5e-07 28.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 Creatininase PF02633.9 KKK20348.1 - 1.6e-05 24.0 0.0 3.2e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Creatinine amidohydrolase Cpn60_TCP1 PF00118.19 KKK20350.1 - 3e-131 438.3 4.8 4.6e-123 411.4 2.7 2.0 2 0 0 2 2 2 2 TCP-1/cpn60 chaperonin family Peptidase_M48 PF01435.13 KKK20350.1 - 8.8e-34 117.0 0.3 3.9e-33 114.8 0.1 2.0 2 0 0 2 2 2 1 Peptidase family M48 DUF2052 PF09747.4 KKK20350.1 - 0.0033 17.3 1.6 0.0062 16.4 1.1 1.3 1 0 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) Ribosomal_60s PF00428.14 KKK20350.1 - 0.1 13.0 10.9 0.34 11.3 7.6 1.9 1 0 0 1 1 1 0 60s Acidic ribosomal protein BUD22 PF09073.5 KKK20350.1 - 0.23 10.4 5.8 0.39 9.7 4.0 1.3 1 0 0 1 1 1 0 BUD22 CobT PF06213.7 KKK20350.1 - 0.33 10.0 11.9 0.092 11.8 6.0 1.7 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT Myc_N PF01056.13 KKK20350.1 - 0.37 9.9 7.1 0.58 9.2 4.9 1.2 1 0 0 1 1 1 0 Myc amino-terminal region Daxx PF03344.10 KKK20350.1 - 1.4 7.3 9.9 2 6.7 6.8 1.1 1 0 0 1 1 1 0 Daxx Family Sigma70_ner PF04546.8 KKK20350.1 - 1.4 8.4 10.7 4 6.9 7.4 1.7 1 0 0 1 1 1 0 Sigma-70, non-essential region TRAP_alpha PF03896.11 KKK20350.1 - 2 7.3 6.3 3.5 6.5 4.3 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit NOA36 PF06524.7 KKK20350.1 - 2.6 7.2 7.5 4.1 6.5 5.2 1.2 1 0 0 1 1 1 0 NOA36 protein Nop14 PF04147.7 KKK20350.1 - 3.5 5.4 11.4 5.6 4.7 7.9 1.2 1 0 0 1 1 1 0 Nop14-like family Fungal_trans_2 PF11951.3 KKK20351.1 - 1.1e-72 244.7 0.0 3.6e-36 124.5 0.1 2.1 1 1 1 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK20351.1 - 1.2e-05 25.1 11.2 2e-05 24.4 7.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AAA PF00004.24 KKK20352.1 - 3.2e-06 27.3 0.0 1.1e-05 25.6 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KKK20352.1 - 0.00015 22.5 0.0 0.00082 20.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 KKK20352.1 - 0.0019 17.2 0.0 0.0029 16.7 0.0 1.2 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 KKK20352.1 - 0.0027 17.4 0.1 0.0048 16.6 0.0 1.4 1 0 0 1 1 1 1 Part of AAA domain AAA_25 PF13481.1 KKK20352.1 - 0.003 16.9 0.0 0.0047 16.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KKK20352.1 - 0.01 15.5 0.0 0.016 14.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) KaiC PF06745.8 KKK20352.1 - 0.014 14.5 0.0 0.019 14.0 0.0 1.2 1 0 0 1 1 1 0 KaiC BCS1_N PF08740.6 KKK20352.1 - 0.015 14.9 0.1 0.019 14.5 0.1 1.2 1 0 0 1 1 1 0 BCS1 N terminal AAA_16 PF13191.1 KKK20352.1 - 0.033 14.1 0.0 0.05 13.5 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain Mg_chelatase PF01078.16 KKK20352.1 - 0.054 12.6 0.0 0.09 11.9 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 KKK20352.1 - 0.083 13.1 0.0 0.16 12.3 0.0 1.5 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.12 KKK20352.1 - 0.085 12.2 0.2 0.16 11.3 0.1 1.4 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA_28 PF13521.1 KKK20352.1 - 0.093 12.6 0.1 0.2 11.6 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 KKK20352.1 - 0.1 12.7 0.1 0.22 11.6 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 KKK20352.1 - 0.11 12.4 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 KKK20352.1 - 0.12 11.8 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Velvet PF11754.3 KKK20353.1 - 2.6e-66 223.1 0.0 3.4e-66 222.7 0.0 1.1 1 0 0 1 1 1 1 Velvet factor Ins_P5_2-kin PF06090.7 KKK20354.1 - 1.6e-75 254.0 0.0 1.9e-75 253.8 0.0 1.0 1 0 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase DUF77 PF01910.12 KKK20355.1 - 8.8e-12 44.5 0.1 3.1e-10 39.5 0.0 2.1 2 0 0 2 2 2 2 Domain of unknown function DUF77 YEATS PF03366.11 KKK20356.1 - 3.5e-36 122.7 1.4 5.3e-36 122.2 1.0 1.3 1 0 0 1 1 1 1 YEATS family DUF334 PF03904.8 KKK20356.1 - 0.23 10.7 1.4 0.46 9.7 0.8 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF334) NAD_binding_10 PF13460.1 KKK20357.1 - 2.6e-11 43.8 0.0 4.1e-10 39.9 0.0 2.2 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KKK20357.1 - 4.3e-07 29.6 0.0 9.1e-07 28.5 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KKK20357.1 - 6.7e-06 25.0 0.0 1.5e-05 23.8 0.0 1.6 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 KKK20357.1 - 1.8e-05 24.7 0.0 3.1e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.7 KKK20357.1 - 0.0083 15.0 0.0 0.81 8.5 0.0 2.4 2 0 0 2 2 2 2 Male sterility protein Mito_fiss_reg PF05308.6 KKK20358.1 - 0.014 14.8 1.2 0.014 14.8 0.8 2.1 2 0 0 2 2 2 0 Mitochondrial fission regulator Auxin_repressed PF05564.7 KKK20358.1 - 7.6 7.1 9.1 2.2 8.9 0.1 3.4 2 1 0 3 3 3 0 Dormancy/auxin associated protein gag_pre-integrs PF13976.1 KKK20360.1 - 0.095 12.3 0.1 0.22 11.1 0.1 1.5 1 0 0 1 1 1 0 GAG-pre-integrase domain Aminotran_5 PF00266.14 KKK20362.1 - 2.1e-07 30.0 0.0 1.4e-06 27.3 0.0 2.0 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 KKK20362.1 - 0.023 13.7 0.0 0.032 13.2 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family IDO PF01231.13 KKK20363.1 - 1.5e-162 540.9 0.0 1.7e-162 540.7 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase Fungal_trans PF04082.13 KKK20367.1 - 7.7e-28 97.0 0.0 1.2e-27 96.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK20367.1 - 7.1e-09 35.4 12.6 1.1e-08 34.8 8.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 KKK20368.1 - 3.6e-37 127.9 14.3 8.1e-29 100.4 0.0 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KKK20368.1 - 3.4e-10 39.1 5.3 6.3e-10 38.2 3.7 1.4 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_2 PF13347.1 KKK20368.1 - 1.3e-05 23.7 3.3 1.3e-05 23.7 2.3 2.6 2 1 0 2 2 2 1 MFS/sugar transport protein Adenylsucc_synt PF00709.16 KKK20369.1 - 2.1e-153 510.9 0.0 2.4e-153 510.7 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase DnaJ PF00226.26 KKK20370.1 - 5.3e-22 77.3 0.7 1e-21 76.4 0.5 1.5 1 0 0 1 1 1 1 DnaJ domain ADH_zinc_N PF00107.21 KKK20371.1 - 8.4e-22 77.1 0.0 1.3e-21 76.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KKK20371.1 - 5.7e-07 30.4 0.0 1.2e-06 29.3 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DEAD PF00270.24 KKK20372.1 - 1.3e-43 148.4 0.0 3.7e-43 146.9 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KKK20372.1 - 7.8e-22 76.9 0.5 3e-20 71.8 0.1 3.0 2 1 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KKK20372.1 - 0.0031 17.3 0.0 0.0069 16.2 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SecA_DEAD PF07517.9 KKK20372.1 - 0.032 13.5 0.1 0.13 11.5 0.1 1.9 1 1 0 1 1 1 0 SecA DEAD-like domain AAA_22 PF13401.1 KKK20372.1 - 0.055 13.6 0.0 0.45 10.6 0.0 2.5 3 1 0 3 3 3 0 AAA domain HEAT PF02985.17 KKK20373.1 - 2e-12 46.0 11.0 0.00024 20.9 0.1 9.0 9 0 0 9 9 9 2 HEAT repeat HEAT_EZ PF13513.1 KKK20373.1 - 4.5e-11 42.8 12.2 8.8e-09 35.6 0.1 6.9 7 2 1 8 8 8 1 HEAT-like repeat HEAT_2 PF13646.1 KKK20373.1 - 5.3e-11 42.6 8.8 1.7e-05 25.0 0.0 6.5 3 2 4 7 7 7 4 HEAT repeats IBN_N PF03810.14 KKK20373.1 - 1.3e-08 34.6 5.0 2.2e-08 33.8 0.1 3.7 5 0 0 5 5 5 1 Importin-beta N-terminal domain CLASP_N PF12348.3 KKK20373.1 - 1e-05 24.9 3.2 0.53 9.5 0.0 5.1 3 1 1 5 5 5 2 CLASP N terminal HEAT_PBS PF03130.11 KKK20373.1 - 0.00033 20.8 0.0 6.6 7.5 0.0 5.3 5 0 0 5 5 5 1 PBS lyase HEAT-like repeat Arm PF00514.18 KKK20373.1 - 0.0042 16.8 0.6 4.7 7.1 0.0 3.3 2 0 0 2 2 2 2 Armadillo/beta-catenin-like repeat Ribosomal_S8 PF00410.14 KKK20374.1 - 8.8e-18 64.3 0.0 1.5e-17 63.6 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S8 His_Phos_1 PF00300.17 KKK20374.1 - 1.4e-17 64.2 0.0 1.9e-17 63.7 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) PINIT PF14324.1 KKK20374.1 - 0.078 13.0 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 PINIT domain Apc4 PF12896.2 KKK20376.1 - 6.8e-70 234.6 2.9 9.3e-70 234.1 2.0 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 Apc4_WD40 PF12894.2 KKK20376.1 - 2.5e-18 65.3 0.0 1.2e-16 59.8 0.0 2.6 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.27 KKK20376.1 - 0.0019 18.0 0.0 0.036 13.9 0.0 3.0 3 0 0 3 3 3 1 WD domain, G-beta repeat Herpes_capsid PF06112.6 KKK20377.1 - 1.6 8.7 6.4 2.9 7.9 4.4 1.4 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein VWA PF00092.23 KKK20378.1 - 2.8e-05 23.9 0.0 0.12 12.0 0.0 2.1 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_2 PF13519.1 KKK20378.1 - 4.7e-05 23.5 0.0 7e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.1 KKK20378.1 - 0.011 15.4 0.0 0.031 13.9 0.0 1.7 1 1 0 1 1 1 0 von Willebrand factor type A domain V-SNARE PF05008.10 KKK20379.1 - 0.22 11.7 2.4 0.52 10.5 1.7 1.7 1 0 0 1 1 1 0 Vesicle transport v-SNARE protein N-terminus Cu-oxidase_3 PF07732.10 KKK20380.1 - 1.6e-36 124.5 0.1 1.1e-35 121.8 0.0 2.4 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 KKK20380.1 - 5.5e-33 113.3 2.0 3.2e-26 91.5 0.0 3.7 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 KKK20380.1 - 7.8e-16 58.3 0.0 1.4e-14 54.2 0.0 2.9 3 1 0 3 3 3 1 Multicopper oxidase HLH PF00010.21 KKK20381.1 - 7.5e-08 31.9 0.0 1.5e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain CAF-1_p150 PF11600.3 KKK20381.1 - 0.86 8.9 7.5 1 8.6 5.2 1.2 1 1 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal GFA PF04828.9 KKK20382.1 - 0.00039 20.2 0.9 0.00058 19.7 0.0 1.8 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme CybS PF05328.7 KKK20383.1 - 6.4e-53 177.9 0.0 8.1e-53 177.5 0.0 1.1 1 0 0 1 1 1 1 CybS Maf PF02545.9 KKK20384.1 - 8.1e-44 149.0 0.0 1.1e-43 148.7 0.0 1.1 1 0 0 1 1 1 1 Maf-like protein p450 PF00067.17 KKK20398.1 - 3.8e-22 78.4 0.0 7.1e-22 77.5 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 Ribosomal_L1 PF00687.16 KKK20399.1 - 1.8e-16 60.1 0.3 1.9e-16 60.0 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Flavodoxin_1 PF00258.20 KKK20400.1 - 4.5e-10 39.6 0.0 6.6e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin FMN_red PF03358.10 KKK20400.1 - 1.6e-08 34.2 0.0 2e-08 33.8 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.12 KKK20400.1 - 4.9e-07 29.4 0.0 6.2e-07 29.1 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_4 PF12682.2 KKK20400.1 - 0.018 14.3 0.1 0.041 13.2 0.1 1.6 1 1 0 1 1 1 0 Flavodoxin Flavodoxin_5 PF12724.2 KKK20400.1 - 0.074 13.0 0.0 0.15 12.0 0.0 1.5 1 1 0 1 1 1 0 Flavodoxin domain DUF3752 PF12572.3 KKK20401.1 - 3.2e-42 144.2 11.7 3.2e-42 144.2 8.1 1.8 3 0 0 3 3 3 1 Protein of unknown function (DUF3752) DUF4407 PF14362.1 KKK20401.1 - 0.1 11.5 3.0 0.13 11.1 2.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Cwf_Cwc_15 PF04889.7 KKK20401.1 - 2.6 7.6 18.5 1.5 8.5 4.5 2.3 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein DUF4337 PF14235.1 KKK20401.1 - 4.2 7.1 5.5 8.8 6.1 3.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) NPL4 PF05021.10 KKK20402.1 - 6.5e-125 416.3 0.0 8.1e-125 416.0 0.0 1.1 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.10 KKK20402.1 - 2.4e-72 241.4 0.1 3.6e-72 240.8 0.1 1.3 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.3 KKK20402.1 - 0.011 15.9 0.0 0.1 12.9 0.0 2.3 1 1 0 1 1 1 0 Nuclear pore localisation protein NPL4 DUF2080 PF09853.4 KKK20402.1 - 0.04 13.6 0.0 0.13 11.9 0.0 2.0 2 0 0 2 2 2 0 Putative transposon-encoded protein (DUF2080) eIF-3_zeta PF05091.7 KKK20402.1 - 0.2 10.2 0.0 0.29 9.6 0.0 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF2417 PF10329.4 KKK20403.1 - 3.8e-88 294.8 0.8 5.7e-88 294.2 0.5 1.3 1 0 0 1 1 1 1 Region of unknown function (DUF2417) Abhydrolase_6 PF12697.2 KKK20403.1 - 5.2e-09 36.3 0.1 9.6e-09 35.4 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family zf-CCCH PF00642.19 KKK20404.1 - 5.1e-19 67.5 28.9 5.4e-07 29.1 0.8 5.3 5 0 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3H1 PF10650.4 KKK20404.1 - 0.0084 15.5 3.6 0.94 9.0 0.1 3.1 2 0 0 2 2 2 2 Putative zinc-finger domain Abhydrolase_6 PF12697.2 KKK20405.1 - 6e-22 78.6 0.7 8.1e-22 78.2 0.5 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KKK20405.1 - 3.4e-08 33.3 0.0 5.9e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KKK20405.1 - 0.00072 19.1 0.0 0.39 10.2 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Lipase_3 PF01764.20 KKK20405.1 - 0.044 13.3 1.3 0.23 11.0 0.9 2.0 1 1 0 1 1 1 0 Lipase (class 3) WD40 PF00400.27 KKK20406.1 - 4.9e-55 181.5 19.4 4e-10 39.1 0.2 6.8 7 0 0 7 7 7 6 WD domain, G-beta repeat TFIID_90kDa PF04494.10 KKK20406.1 - 7e-47 159.0 0.0 1e-46 158.5 0.0 1.2 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit LisH PF08513.6 KKK20406.1 - 1.1e-06 28.2 0.0 2.4e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 LisH Nup160 PF11715.3 KKK20406.1 - 6.5e-05 21.2 2.0 0.035 12.2 0.0 3.1 2 1 1 3 3 3 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 KKK20406.1 - 0.013 14.2 0.1 6 5.5 0.0 3.8 3 1 1 4 4 4 0 Nup133 N terminal like DUF3550 PF12070.3 KKK20406.1 - 0.088 11.5 0.0 0.13 10.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3550/UPF0682) F_actin_cap_B PF01115.12 KKK20409.1 - 1.4e-89 299.4 0.0 1.6e-75 253.4 0.0 2.2 1 1 1 2 2 2 2 F-actin capping protein, beta subunit ResIII PF04851.10 KKK20409.1 - 3.1e-19 69.5 0.0 6.9e-19 68.3 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 KKK20409.1 - 1.2e-18 66.7 0.1 3.9e-18 65.0 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KKK20409.1 - 1.5e-18 66.8 0.0 4.6e-18 65.2 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KKK20409.1 - 0.022 14.8 0.0 0.064 13.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain WD40 PF00400.27 KKK20410.1 - 0.13 12.2 1.3 1.1 9.2 0.0 2.9 3 0 0 3 3 3 0 WD domain, G-beta repeat HD PF01966.17 KKK20411.1 - 1.3e-06 28.4 1.0 4.7e-06 26.6 0.1 2.0 2 0 0 2 2 2 1 HD domain Med11 PF10280.4 KKK20412.1 - 3.5e-37 127.0 0.0 4.4e-37 126.7 0.0 1.1 1 0 0 1 1 1 1 Mediator complex protein Med29 PF11568.3 KKK20412.1 - 0.00048 20.2 0.0 0.00071 19.6 0.0 1.3 1 0 0 1 1 1 1 Mediator complex subunit 29 PTS_IIA PF02255.11 KKK20412.1 - 0.077 12.8 0.2 0.13 12.1 0.1 1.4 1 0 0 1 1 1 0 PTS system, Lactose/Cellobiose specific IIA subunit DUF3224 PF11528.3 KKK20436.1 - 2.5e-06 27.0 0.0 2.7e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3224) TPR_12 PF13424.1 KKK20439.1 - 1.7e-09 37.4 0.6 0.039 13.9 0.0 4.7 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 KKK20439.1 - 4.5e-08 32.6 2.7 1.1e-05 24.9 0.4 3.7 3 1 1 4 4 4 2 TPR repeat AAA_16 PF13191.1 KKK20439.1 - 2.7e-06 27.4 0.0 2e-05 24.6 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain NACHT PF05729.7 KKK20439.1 - 7.4e-05 22.4 0.0 0.00049 19.8 0.0 2.4 2 0 0 2 2 2 1 NACHT domain TPR_2 PF07719.12 KKK20439.1 - 0.00031 20.4 9.4 0.0025 17.5 0.1 5.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.1 KKK20439.1 - 0.0013 18.3 0.2 3.3 7.7 0.1 3.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 KKK20439.1 - 0.0017 18.8 7.8 0.11 13.2 0.0 5.6 4 1 1 5 5 5 1 Tetratricopeptide repeat AAA_22 PF13401.1 KKK20439.1 - 0.0018 18.4 0.0 0.013 15.6 0.0 2.5 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.4 KKK20439.1 - 0.0025 16.8 0.1 0.074 12.0 0.0 2.5 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) TPR_19 PF14559.1 KKK20439.1 - 0.0037 17.5 5.5 0.18 12.1 0.1 4.7 4 1 0 5 5 5 1 Tetratricopeptide repeat RPN7 PF10602.4 KKK20439.1 - 0.0056 16.0 0.9 0.83 9.0 0.3 3.1 2 0 0 2 2 2 1 26S proteasome subunit RPN7 AAA_17 PF13207.1 KKK20439.1 - 0.0081 16.9 0.1 0.064 14.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain TPR_1 PF00515.23 KKK20439.1 - 0.011 15.2 6.1 0.02 14.4 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat MNE1 PF13762.1 KKK20439.1 - 0.016 15.2 0.2 3.7 7.6 0.1 3.4 3 1 0 3 3 3 0 Mitochondrial splicing apparatus component TPR_7 PF13176.1 KKK20439.1 - 0.017 14.8 3.6 0.13 12.1 0.0 3.7 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_10 PF13374.1 KKK20439.1 - 0.028 14.3 0.5 13 5.9 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.1 KKK20439.1 - 0.096 12.9 0.2 2.6 8.4 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat AA_permease PF00324.16 KKK20440.1 - 1.1e-106 357.0 37.5 1.4e-106 356.7 26.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KKK20440.1 - 2.4e-37 128.4 41.6 3e-37 128.1 28.9 1.1 1 0 0 1 1 1 1 Amino acid permease Tweety PF04906.8 KKK20440.1 - 1.4 7.2 4.7 2.3 6.5 3.2 1.3 1 0 0 1 1 1 0 Tweety MFS_1 PF07690.11 KKK20441.1 - 1.5e-42 145.5 52.8 1.5e-42 145.5 36.6 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KKK20441.1 - 1.2e-08 33.9 11.4 1.2e-08 33.9 7.9 3.9 2 1 0 3 3 3 1 Sugar (and other) transporter MFS_1 PF07690.11 KKK20442.1 - 4.9e-52 176.7 27.5 4.9e-52 176.7 19.1 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KKK20442.1 - 3.1e-13 49.1 8.0 3.1e-13 49.1 5.6 2.8 3 0 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.8 KKK20442.1 - 2.7e-06 25.8 3.4 6.1e-06 24.7 2.4 1.5 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF791 PF05631.9 KKK20442.1 - 0.00051 18.8 4.9 0.00063 18.5 1.6 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF791) MFS_1_like PF12832.2 KKK20442.1 - 0.0041 16.8 0.6 1.6 8.5 0.5 2.9 2 0 0 2 2 2 2 MFS_1 like family DUF3353 PF11833.3 KKK20442.1 - 0.42 10.0 5.3 1.4 8.3 3.7 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3353) Fungal_trans PF04082.13 KKK20443.1 - 9.2e-16 57.4 0.1 1.7e-15 56.6 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK20443.1 - 3.8e-07 29.8 10.1 3.8e-07 29.8 7.0 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 KKK20444.1 - 1.2e-23 83.4 18.7 2e-23 82.6 12.9 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily Fungal_trans PF04082.13 KKK20445.1 - 4.6e-14 51.9 0.3 7.9e-14 51.1 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK20445.1 - 6.3e-08 32.4 11.2 1.4e-07 31.2 7.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dyp_perox PF04261.7 KKK20446.1 - 9e-94 313.7 0.0 1e-93 313.5 0.0 1.0 1 0 0 1 1 1 1 Dyp-type peroxidase family adh_short PF00106.20 KKK20448.1 - 6.8e-18 65.1 0.5 1.7e-17 63.8 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KKK20448.1 - 8.3e-12 45.1 0.0 2.6e-11 43.5 0.0 1.7 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.10 KKK20448.1 - 1.7e-05 23.9 0.0 2.6e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 KKK20448.1 - 0.00022 20.7 0.0 0.0018 17.7 0.0 2.3 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 KKK20448.1 - 0.0047 17.0 0.0 0.0091 16.1 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Lipoprotein_18 PF06804.6 KKK20448.1 - 0.046 12.4 0.0 0.37 9.5 0.0 1.9 2 0 0 2 2 2 0 NlpB/DapX lipoprotein NAD_binding_4 PF07993.7 KKK20448.1 - 0.099 11.5 0.1 0.71 8.7 0.0 2.2 3 0 0 3 3 3 0 Male sterility protein TLP-20 PF06088.6 KKK20449.1 - 0.13 11.9 4.6 0.16 11.6 3.2 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) BAF1_ABF1 PF04684.8 KKK20449.1 - 2.3 7.0 11.9 2.4 6.9 8.2 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Fungal_trans_2 PF11951.3 KKK20450.1 - 0.0032 16.1 3.3 0.33 9.4 2.0 2.4 2 1 0 2 2 2 2 Fungal specific transcription factor domain DUF3112 PF11309.3 KKK20452.1 - 4e-51 172.9 7.2 2e-46 157.6 0.1 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3112) ELO PF01151.13 KKK20452.1 - 0.067 12.4 1.1 0.14 11.4 0.1 2.1 2 1 0 2 2 2 0 GNS1/SUR4 family OxoDH_E1alpha_N PF12573.3 KKK20452.1 - 0.15 11.6 0.0 0.32 10.5 0.0 1.5 1 0 0 1 1 1 0 2-oxoisovalerate dehydrogenase E1 alpha subunit N terminal ABC2_membrane_5 PF13346.1 KKK20452.1 - 0.57 9.4 16.8 0.031 13.5 1.8 2.7 2 1 0 2 2 2 0 ABC-2 family transporter protein PLAC8 PF04749.12 KKK20452.1 - 0.93 10.0 3.7 3 8.4 0.0 2.7 2 1 0 2 2 2 0 PLAC8 family Ninjurin PF04923.7 KKK20452.1 - 1.3 8.7 5.8 1.7 8.3 0.7 2.7 2 1 0 2 2 2 0 Ninjurin Zn_clus PF00172.13 KKK20453.1 - 2.8e-05 23.9 12.5 4.9e-05 23.1 8.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Clr5 PF14420.1 KKK20454.1 - 9.6e-12 44.6 0.4 2e-11 43.5 0.3 1.6 1 0 0 1 1 1 1 Clr5 domain TauD PF02668.11 KKK20455.1 - 2.9e-47 161.5 0.0 3.7e-47 161.1 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Aldo_ket_red PF00248.16 KKK20456.1 - 2.7e-58 197.0 0.0 3.4e-58 196.7 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family FGGY_C PF02782.11 KKK20471.1 - 3.1e-74 248.8 0.8 5.8e-74 248.0 0.6 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 KKK20471.1 - 3.8e-60 203.2 0.0 5e-60 202.8 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.15 KKK20471.1 - 0.0037 16.6 0.6 0.079 12.2 0.0 2.1 2 0 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family DUF3429 PF11911.3 KKK20472.1 - 1.8e-40 138.1 11.0 2.5e-40 137.7 7.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) Allene_ox_cyc PF06351.6 KKK20472.1 - 0.14 11.5 0.1 0.25 10.7 0.1 1.3 1 0 0 1 1 1 0 Allene oxide cyclase DUF1162 PF06650.7 KKK20473.1 - 9.7e-91 303.8 0.0 2.5e-89 299.1 0.0 2.9 4 0 0 4 4 4 1 Protein of unknown function (DUF1162) Chorein_N PF12624.2 KKK20473.1 - 6.2e-42 141.8 0.0 1.9e-41 140.2 0.0 1.9 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter ATG_C PF09333.6 KKK20473.1 - 1.2e-06 28.6 0.3 6.5e-06 26.2 0.0 2.4 3 0 0 3 3 3 1 ATG C terminal domain MFS_1 PF07690.11 KKK20474.1 - 1.3e-20 73.4 38.1 2.3e-15 56.1 15.1 2.9 2 1 1 3 3 3 2 Major Facilitator Superfamily MFS_3 PF05977.8 KKK20474.1 - 0.0001 20.6 16.0 0.0036 15.4 1.4 2.6 3 0 0 3 3 3 2 Transmembrane secretion effector GCFC PF07842.7 KKK20475.1 - 5.9e-89 298.0 3.6 5.9e-89 298.0 2.5 1.5 2 0 0 2 2 2 1 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.18 KKK20475.1 - 5.7e-17 61.2 1.0 1.3e-16 60.0 0.7 1.7 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 KKK20475.1 - 1.8e-09 37.3 0.3 8.1e-09 35.2 0.2 2.2 1 0 0 1 1 1 1 DExH-box splicing factor binding site DUF3425 PF11905.3 KKK20475.1 - 0.0062 16.4 0.3 0.017 14.9 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) Sod_Fe_C PF02777.13 KKK20476.1 - 5.4e-40 135.5 1.4 5.8e-40 135.3 0.3 1.5 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 KKK20476.1 - 2.9e-17 62.7 6.6 5.6e-17 61.7 4.6 1.5 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Imm15 PF15590.1 KKK20476.1 - 0.00093 18.2 0.6 0.71 8.9 0.0 3.4 4 0 0 4 4 4 2 Immunity protein 15 F-box PF00646.28 KKK20477.1 - 0.013 15.1 0.0 0.031 13.9 0.0 1.6 1 0 0 1 1 1 0 F-box domain Microtub_assoc PF07989.6 KKK20478.1 - 0.0024 17.6 0.9 0.0024 17.6 0.6 2.5 1 1 1 2 2 2 1 Microtubule associated DUF972 PF06156.8 KKK20478.1 - 1.7 9.0 8.3 6.1 7.2 5.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF972) AAA_23 PF13476.1 KKK20478.1 - 1.8 8.8 11.3 3.2 8.0 7.8 1.3 1 0 0 1 1 1 0 AAA domain DUF3584 PF12128.3 KKK20478.1 - 2 5.6 16.2 2.8 5.1 11.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) FlaC_arch PF05377.6 KKK20478.1 - 3.5 7.5 5.7 16 5.5 3.6 2.4 1 1 0 1 1 1 0 Flagella accessory protein C (FlaC) IncA PF04156.9 KKK20478.1 - 6 6.4 19.9 11 5.5 13.8 1.4 1 0 0 1 1 1 0 IncA protein BLOC1_2 PF10046.4 KKK20478.1 - 8.7 6.5 8.3 26 5.0 5.2 2.0 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Sld5 PF05916.6 KKK20479.1 - 4.3e-16 59.1 0.0 5.5e-16 58.8 0.0 1.1 1 0 0 1 1 1 1 GINS complex protein Peptidase_M41 PF01434.13 KKK20480.1 - 1.4e-65 220.7 0.1 2.7e-65 219.8 0.1 1.5 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 KKK20480.1 - 1.2e-42 145.2 0.0 3.9e-42 143.5 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KKK20480.1 - 6e-06 27.0 0.0 1.9e-05 25.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KKK20480.1 - 7.7e-06 26.0 0.1 3.7e-05 23.7 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.9 KKK20480.1 - 9.3e-06 25.4 0.0 3.6e-05 23.4 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.8 KKK20480.1 - 6.7e-05 21.7 1.8 0.00011 21.0 0.0 2.1 2 0 0 2 2 2 1 TIP49 C-terminus RuvB_N PF05496.7 KKK20480.1 - 0.0002 20.4 0.0 0.00056 19.0 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 KKK20480.1 - 0.00043 20.4 2.9 0.011 15.8 0.2 3.1 2 1 0 2 2 1 1 AAA domain AAA_33 PF13671.1 KKK20480.1 - 0.0011 18.8 0.1 0.006 16.4 0.0 2.4 3 0 0 3 3 2 1 AAA domain AAA_19 PF13245.1 KKK20480.1 - 0.0016 18.1 0.3 0.0047 16.6 0.2 1.7 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 KKK20480.1 - 0.0023 17.3 0.0 0.0045 16.4 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_25 PF13481.1 KKK20480.1 - 0.0072 15.7 4.0 0.083 12.2 0.3 2.7 2 1 1 3 3 3 1 AAA domain Zeta_toxin PF06414.7 KKK20480.1 - 0.008 15.3 1.7 0.022 13.8 0.2 2.3 2 1 0 2 2 2 1 Zeta toxin AAA_14 PF13173.1 KKK20480.1 - 0.01 15.7 0.0 0.024 14.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.9 KKK20480.1 - 0.013 15.3 0.0 0.042 13.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) NACHT PF05729.7 KKK20480.1 - 0.014 15.0 0.5 1.1 8.8 0.1 2.5 2 0 0 2 2 2 0 NACHT domain AAA_28 PF13521.1 KKK20480.1 - 0.015 15.2 0.0 0.041 13.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 KKK20480.1 - 0.02 14.0 0.2 0.04 13.0 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 KKK20480.1 - 0.048 13.9 0.0 0.13 12.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 KKK20480.1 - 0.048 12.7 0.5 1.3 8.0 0.0 2.7 3 0 0 3 3 3 0 KaiC DUF815 PF05673.8 KKK20480.1 - 0.05 12.5 0.0 0.11 11.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) NTP_transferase PF00483.18 KKK20482.1 - 7.8e-48 162.9 0.0 1.5e-47 162.0 0.0 1.4 2 0 0 2 2 2 1 Nucleotidyl transferase Hexapep PF00132.19 KKK20482.1 - 3.7e-16 57.8 14.7 8.5e-10 37.7 2.1 4.2 1 1 3 4 4 4 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 KKK20482.1 - 7.4e-11 42.3 0.0 1.2e-10 41.7 0.0 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.1 KKK20482.1 - 1.3e-06 27.8 2.6 1.3e-06 27.8 1.8 2.9 3 0 0 3 3 3 1 Hexapeptide repeat of succinyl-transferase IspD PF01128.14 KKK20482.1 - 0.15 11.5 0.0 0.25 10.8 0.0 1.3 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Pkinase PF00069.20 KKK20484.1 - 7.4e-69 231.7 0.0 1e-68 231.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK20484.1 - 2.8e-36 124.9 0.0 4.2e-36 124.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KKK20484.1 - 1.5e-05 24.1 0.0 2.7e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like PAT1 PF09770.4 KKK20484.1 - 3 5.9 15.4 3.8 5.6 10.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 zf-Tim10_DDP PF02953.10 KKK20485.1 - 1.1e-22 79.0 1.3 1.4e-22 78.7 0.9 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger eIF3_subunit PF08597.5 KKK20485.1 - 0.024 14.2 0.0 0.024 14.2 0.0 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Condensin2nSMC PF12422.3 KKK20485.1 - 0.044 13.5 0.1 0.054 13.2 0.1 1.1 1 0 0 1 1 1 0 Condensin II non structural maintenance of chromosomes subunit Rep_fac_C PF08542.6 KKK20486.1 - 1.7e-23 82.3 0.0 8.4e-23 80.1 0.0 2.1 2 0 0 2 2 2 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 KKK20486.1 - 2.4e-11 43.5 0.1 4.3e-11 42.7 0.1 1.4 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 KKK20486.1 - 9.6e-06 25.8 0.2 2.3e-05 24.5 0.2 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KKK20486.1 - 6.2e-05 23.1 0.7 0.00037 20.6 0.4 2.4 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.1 KKK20486.1 - 0.0063 16.5 1.3 0.48 10.3 0.0 2.6 2 1 1 3 3 3 1 AAA ATPase domain Sigma54_activ_2 PF14532.1 KKK20486.1 - 0.0066 16.5 0.4 0.29 11.1 0.2 2.4 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_10 PF12846.2 KKK20486.1 - 0.032 13.6 0.1 1.1 8.5 0.0 2.1 1 1 0 2 2 2 0 AAA-like domain ABC_tran PF00005.22 KKK20486.1 - 0.034 14.4 0.1 0.071 13.4 0.1 1.6 1 1 0 1 1 1 0 ABC transporter AAA_33 PF13671.1 KKK20486.1 - 0.038 13.8 0.0 0.074 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain SNF2_N PF00176.18 KKK20486.1 - 0.045 12.5 0.1 0.065 12.0 0.1 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain Rad17 PF03215.10 KKK20486.1 - 0.063 11.9 0.0 0.1 11.2 0.0 1.4 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein Ribosomal_L16 PF00252.13 KKK20487.1 - 1e-29 102.9 0.2 1.3e-29 102.6 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e RFC1 PF08519.7 KKK20488.1 - 7.9e-61 204.3 0.1 1.2e-59 200.5 0.0 2.3 2 0 0 2 2 2 1 Replication factor RFC1 C terminal domain BRCT PF00533.21 KKK20488.1 - 6.2e-14 51.9 0.0 2.7e-13 49.8 0.0 2.2 2 0 0 2 2 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.24 KKK20488.1 - 1.2e-10 41.6 0.3 3.9e-10 40.0 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KKK20488.1 - 1.1e-07 32.0 0.0 3e-07 30.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KKK20488.1 - 4e-05 24.4 5.1 0.00027 21.7 0.0 3.4 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.1 KKK20488.1 - 0.00037 20.5 0.0 0.011 15.6 0.0 2.7 1 1 1 2 2 2 1 AAA ATPase domain DNA_pol3_delta PF06144.8 KKK20488.1 - 0.0025 17.3 0.0 0.0056 16.2 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.10 KKK20488.1 - 0.0039 15.9 0.0 0.016 13.8 0.0 1.8 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_33 PF13671.1 KKK20488.1 - 0.0068 16.2 0.0 0.023 14.5 0.0 2.0 1 1 0 1 1 1 1 AAA domain Bac_DnaA PF00308.13 KKK20488.1 - 0.0083 15.7 0.2 0.89 9.1 0.1 2.6 3 0 0 3 3 3 1 Bacterial dnaA protein RuvB_N PF05496.7 KKK20488.1 - 0.0095 15.0 0.0 0.02 13.9 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_28 PF13521.1 KKK20488.1 - 0.03 14.2 0.1 0.23 11.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.9 KKK20488.1 - 0.031 14.0 0.0 0.33 10.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 KKK20488.1 - 0.033 13.6 0.0 0.068 12.6 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_19 PF13245.1 KKK20488.1 - 0.039 13.6 0.1 0.093 12.4 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_18 PF13238.1 KKK20488.1 - 0.05 13.9 0.1 0.05 13.9 0.0 3.3 4 0 0 4 4 4 0 AAA domain PTCB-BRCT PF12738.2 KKK20488.1 - 0.13 12.1 0.0 0.43 10.4 0.0 2.0 1 0 0 1 1 1 0 twin BRCT domain SIN1 PF05422.7 KKK20489.1 - 6.2e-32 110.7 5.3 1.6e-17 63.2 5.1 2.7 2 1 0 2 2 2 2 Stress-activated map kinase interacting protein 1 (SIN1) TUG-UBL1 PF11470.3 KKK20489.1 - 0.035 14.0 0.0 0.084 12.7 0.0 1.7 1 0 0 1 1 1 0 GLUT4 regulating protein TUG PH PF00169.24 KKK20489.1 - 0.04 14.1 0.0 0.1 12.8 0.0 1.7 1 0 0 1 1 1 0 PH domain RBM39linker PF15519.1 KKK20489.1 - 0.072 13.3 0.0 0.22 11.8 0.0 1.8 1 0 0 1 1 1 0 linker between RRM2 and RRM3 domains in RBM39 protein CtaG_Cox11 PF04442.9 KKK20490.1 - 2.4e-57 193.0 0.0 3.1e-57 192.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 PNP_UDP_1 PF01048.15 KKK20491.1 - 7.1e-05 21.8 0.0 0.00011 21.3 0.0 1.2 1 0 0 1 1 1 1 Phosphorylase superfamily Mg_trans_NIPA PF05653.9 KKK20492.1 - 5.1e-91 304.7 22.4 7e-91 304.3 15.5 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EmrE PF13536.1 KKK20492.1 - 1.7e-06 28.1 5.0 1.7e-06 28.1 3.4 3.1 2 1 0 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 KKK20492.1 - 1.4e-05 25.0 7.4 1.4e-05 25.0 5.2 3.0 3 0 0 3 3 3 1 EamA-like transporter family Lectin_leg-like PF03388.8 KKK20493.1 - 3.6e-49 166.9 0.1 4.5e-49 166.6 0.1 1.0 1 0 0 1 1 1 1 Legume-like lectin family HERV-K_env_2 PF13804.1 KKK20494.1 - 0.093 12.2 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Retro-transcribing viruses envelope glycoprotein RTA1 PF04479.8 KKK20495.1 - 3.9e-46 157.3 1.2 6.4e-46 156.6 0.8 1.3 1 0 0 1 1 1 1 RTA1 like protein DUF2975 PF11188.3 KKK20495.1 - 1.2 8.8 7.8 4.6 6.9 0.0 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2975) ICMT PF04140.9 KKK20496.1 - 5.3e-09 36.1 3.8 4.4e-07 30.0 2.7 2.3 1 1 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 KKK20496.1 - 4.2e-07 30.0 4.3 6.8e-06 26.1 0.6 2.5 1 1 1 2 2 2 2 Phospholipid methyltransferase NfeD PF01957.13 KKK20496.1 - 0.024 14.7 0.2 0.77 9.8 0.1 2.7 3 0 0 3 3 3 0 NfeD-like C-terminal, partner-binding ERG4_ERG24 PF01222.12 KKK20496.1 - 0.025 13.1 0.3 0.039 12.4 0.2 1.3 1 0 0 1 1 1 0 Ergosterol biosynthesis ERG4/ERG24 family Aldo_ket_red PF00248.16 KKK20497.1 - 2.1e-52 177.7 0.0 2.4e-52 177.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Fungal_trans_2 PF11951.3 KKK20498.1 - 1.9e-06 26.7 0.1 2.5e-06 26.3 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK20498.1 - 0.0072 16.2 3.2 0.0072 16.2 2.2 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 KKK20499.1 - 9.1e-40 136.4 56.0 9.1e-40 136.4 38.8 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily p450 PF00067.17 KKK20500.1 - 6.2e-71 239.2 0.0 7.2e-71 239.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Tmemb_14 PF03647.8 KKK20501.1 - 1.7e-12 47.5 4.3 2.2e-12 47.1 3.0 1.1 1 0 0 1 1 1 1 Transmembrane proteins 14C DUF2339 PF10101.4 KKK20501.1 - 0.0013 17.0 1.9 0.0015 16.9 1.3 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2339) DUF2530 PF10745.4 KKK20501.1 - 0.012 15.5 1.5 0.19 11.7 0.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2530) Bys1 PF04681.7 KKK20502.1 - 1.1e-15 57.6 0.9 1.3e-15 57.4 0.6 1.0 1 0 0 1 1 1 1 Blastomyces yeast-phase-specific protein MFS_1 PF07690.11 KKK20503.1 - 1.1e-19 70.4 56.0 1.6e-10 40.2 25.1 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2976 PF11190.3 KKK20503.1 - 8.3 6.0 17.0 6.5 6.3 1.8 4.6 3 1 1 4 4 4 0 Protein of unknown function (DUF2976) MmgE_PrpD PF03972.9 KKK20504.1 - 1.8e-66 224.1 0.0 2.2e-66 223.9 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family Acetyltransf_7 PF13508.1 KKK20505.1 - 1.7e-06 28.0 0.1 2.8e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KKK20505.1 - 1.7e-06 27.9 0.2 2.8e-06 27.2 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 KKK20505.1 - 1.1e-05 25.0 0.0 1.8e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 KKK20505.1 - 3.8e-05 23.7 0.1 0.00013 22.1 0.1 1.7 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KKK20505.1 - 0.0053 16.6 0.0 0.015 15.1 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Peptidase_M35 PF02102.10 KKK20506.1 - 3.6e-165 548.9 14.6 4.3e-165 548.6 10.1 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.1 KKK20506.1 - 1.4e-07 32.1 1.8 1.8e-07 31.7 0.7 1.7 2 0 0 2 2 2 1 Lysine-specific metallo-endopeptidase HRXXH PF13933.1 KKK20506.1 - 0.002 17.6 1.8 0.0037 16.7 1.3 1.5 1 1 0 1 1 1 1 Putative peptidase family HD PF01966.17 KKK20507.1 - 2.4e-05 24.3 0.0 3.3e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 HD domain HDOD PF08668.7 KKK20507.1 - 0.0046 16.2 0.1 0.0063 15.8 0.0 1.2 1 0 0 1 1 1 1 HDOD domain Fungal_trans PF04082.13 KKK20508.1 - 2.6e-09 36.3 1.9 4.1e-09 35.6 1.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Aconitase PF00330.15 KKK20509.1 - 2.2e-62 211.0 0.0 1.7e-40 138.9 0.0 2.2 1 1 1 2 2 2 2 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 KKK20509.1 - 1.7e-17 63.7 0.0 3.1e-17 62.9 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain Aconitase_2_N PF06434.8 KKK20509.1 - 0.12 11.8 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Aconitate hydratase 2 N-terminus PEP_mutase PF13714.1 KKK20510.1 - 4.9e-52 176.5 0.2 5.7e-52 176.3 0.1 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.16 KKK20510.1 - 5.9e-19 67.6 0.1 8.2e-19 67.2 0.1 1.2 1 0 0 1 1 1 1 Isocitrate lyase family Pantoate_transf PF02548.10 KKK20510.1 - 0.0077 15.3 0.0 0.1 11.6 0.0 2.3 3 0 0 3 3 3 1 Ketopantoate hydroxymethyltransferase APH PF01636.18 KKK20511.1 - 1.9e-10 40.8 0.2 1.2e-06 28.5 0.3 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family zf-C2H2_2 PF12756.2 KKK20512.1 - 0.0056 16.7 0.2 0.015 15.3 0.2 1.6 1 1 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-Di19 PF05605.7 KKK20512.1 - 0.012 15.7 1.7 0.57 10.3 0.0 2.3 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.1 KKK20512.1 - 0.012 15.8 4.6 0.19 12.1 0.1 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.21 KKK20512.1 - 0.017 15.4 2.0 0.96 9.9 0.1 2.9 3 0 0 3 3 3 0 Zinc finger, C2H2 type DZR PF12773.2 KKK20512.1 - 0.024 14.4 0.1 0.052 13.3 0.0 1.5 1 1 0 1 1 1 0 Double zinc ribbon Acetyltransf_1 PF00583.19 KKK20513.1 - 9.8e-11 41.5 0.1 1.6e-10 40.8 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KKK20513.1 - 8.9e-10 38.5 0.2 1.1e-08 35.0 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KKK20513.1 - 0.0026 17.4 0.1 0.0056 16.4 0.1 1.6 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.1 KKK20513.1 - 0.024 14.6 0.1 0.047 13.6 0.0 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain p450 PF00067.17 KKK20514.1 - 3.3e-51 174.2 0.0 4.4e-51 173.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 PIG-L PF02585.12 KKK20515.1 - 9e-14 52.0 0.1 2.4e-13 50.7 0.0 1.6 1 1 0 1 1 1 1 GlcNAc-PI de-N-acetylase Sugar_tr PF00083.19 KKK20516.1 - 5.8e-73 245.9 17.9 8.5e-73 245.4 12.4 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KKK20516.1 - 3.9e-15 55.4 32.6 4e-15 55.3 20.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily GFO_IDH_MocA PF01408.17 KKK20516.1 - 1.1e-07 32.3 0.0 2.4e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold MFS_2 PF13347.1 KKK20516.1 - 5.3e-07 28.3 24.3 0.00011 20.7 1.6 3.3 3 0 0 3 3 3 2 MFS/sugar transport protein GFO_IDH_MocA_C PF02894.12 KKK20516.1 - 0.00012 21.8 0.0 0.00026 20.7 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain DUF3006 PF11213.3 KKK20516.1 - 0.12 12.1 0.0 0.49 10.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3006) Glyco_hydro_17 PF00332.13 KKK20518.1 - 0.0003 19.9 0.7 0.00056 19.0 0.5 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 HTH_6 PF01418.12 KKK20518.1 - 0.097 12.4 0.0 0.37 10.5 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain, rpiR family Sugar_tr PF00083.19 KKK20519.1 - 1.1e-76 258.2 18.7 1.4e-76 257.9 12.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KKK20519.1 - 3e-30 105.1 21.1 5.2e-28 97.7 7.7 1.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Kinocilin PF15033.1 KKK20519.1 - 0.3 10.5 2.6 0.75 9.3 1.8 1.6 1 0 0 1 1 1 0 Kinocilin protein Ribonuclease PF00545.15 KKK20520.1 - 9.7e-17 60.8 0.5 1.3e-16 60.4 0.3 1.2 1 0 0 1 1 1 1 ribonuclease MARVEL PF01284.18 KKK20521.1 - 0.00026 20.8 0.8 0.0034 17.2 0.1 2.4 2 0 0 2 2 2 1 Membrane-associating domain ABC_tran PF00005.22 KKK20522.1 - 2.2e-49 167.2 0.0 1.1e-27 96.9 0.0 2.8 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 KKK20522.1 - 5.2e-46 157.2 40.6 1.5e-26 93.4 14.4 3.1 3 0 0 3 3 3 3 ABC transporter transmembrane region AAA_21 PF13304.1 KKK20522.1 - 1.9e-10 41.1 0.3 0.14 12.1 0.1 4.3 3 1 0 3 3 3 3 AAA domain AAA_29 PF13555.1 KKK20522.1 - 4.6e-07 29.2 0.9 0.021 14.3 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 KKK20522.1 - 7.4e-07 29.1 0.0 0.035 14.0 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase SMC_N PF02463.14 KKK20522.1 - 7.5e-07 28.6 0.6 0.45 9.7 0.0 3.6 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 KKK20522.1 - 2.9e-06 28.1 0.0 0.033 14.9 0.0 2.9 2 0 0 2 2 2 2 AAA domain Miro PF08477.8 KKK20522.1 - 7.6e-06 26.4 0.1 0.25 11.8 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein AAA_23 PF13476.1 KKK20522.1 - 9e-06 26.1 0.1 0.14 12.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 KKK20522.1 - 9.4e-06 24.8 0.0 0.024 13.7 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin AAA_16 PF13191.1 KKK20522.1 - 2.5e-05 24.3 4.5 0.04 13.8 0.2 3.4 3 1 0 3 3 3 2 AAA ATPase domain Dynamin_N PF00350.18 KKK20522.1 - 5.6e-05 23.0 1.2 0.0079 16.0 0.0 2.7 2 0 0 2 2 2 1 Dynamin family DUF258 PF03193.11 KKK20522.1 - 0.00013 21.2 1.0 0.054 12.6 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 KKK20522.1 - 0.00048 20.2 0.3 0.93 9.6 0.0 3.4 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.1 KKK20522.1 - 0.003 16.9 0.1 0.69 9.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 KKK20522.1 - 0.0033 16.9 0.0 0.51 9.7 0.0 2.5 2 0 0 2 2 2 1 AAA-like domain DUF87 PF01935.12 KKK20522.1 - 0.0077 16.0 0.6 0.21 11.3 0.2 2.3 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_18 PF13238.1 KKK20522.1 - 0.01 16.1 0.8 2.1 8.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 KKK20522.1 - 0.017 14.7 0.3 3.2 7.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.12 KKK20522.1 - 0.025 14.1 1.0 3.7 7.0 0.1 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein MobB PF03205.9 KKK20522.1 - 0.029 14.0 0.2 4 7.1 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B FtsK_SpoIIIE PF01580.13 KKK20522.1 - 0.032 13.6 0.2 2.9 7.2 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA PF00004.24 KKK20522.1 - 0.033 14.3 0.0 1.6 8.9 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ArgK PF03308.11 KKK20522.1 - 0.12 11.0 1.3 3.5 6.3 0.3 2.3 2 0 0 2 2 2 0 ArgK protein AAA_15 PF13175.1 KKK20522.1 - 0.12 11.3 0.0 14 4.5 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain AAA_PrkA PF08298.6 KKK20522.1 - 0.16 10.6 0.1 0.78 8.3 0.0 2.0 2 0 0 2 2 2 0 PrkA AAA domain AAA_28 PF13521.1 KKK20522.1 - 0.17 11.8 1.2 1.2 9.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain Phosphoesterase PF04185.9 KKK20523.1 - 4e-62 210.5 0.3 7.6e-62 209.6 0.2 1.5 1 1 0 1 1 1 1 Phosphoesterase family Glyco_hydro_43 PF04616.9 KKK20524.1 - 4.8e-103 344.1 0.6 1.7e-102 342.4 0.2 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 43 Glyco_hydro_28 PF00295.12 KKK20525.1 - 3.1e-85 286.0 18.5 3.1e-85 286.0 12.8 2.4 3 0 0 3 3 3 1 Glycosyl hydrolases family 28 Pectinesterase PF01095.14 KKK20525.1 - 2.5e-37 128.0 2.8 9.9e-37 126.1 1.0 2.3 2 0 0 2 2 2 1 Pectinesterase Beta_helix PF13229.1 KKK20525.1 - 0.0078 15.9 29.4 0.0078 15.9 20.4 4.9 3 2 2 5 5 5 2 Right handed beta helix region DUF2422 PF10337.4 KKK20526.1 - 1.3e-110 370.4 3.1 2.4e-110 369.5 2.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2422) DUF2421 PF10334.4 KKK20526.1 - 1.2e-56 191.8 0.0 1.1e-54 185.4 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2421) FUSC_2 PF13515.1 KKK20526.1 - 4.3e-09 36.3 14.8 4.3e-09 36.3 10.2 3.7 3 1 0 3 3 3 1 Fusaric acid resistance protein-like PET122 PF05476.6 KKK20526.1 - 0.1 11.8 0.1 0.2 10.9 0.0 1.4 1 0 0 1 1 1 0 PET122 ALMT PF11744.3 KKK20526.1 - 0.4 9.2 11.6 0.097 11.3 5.6 1.7 2 0 0 2 2 2 0 Aluminium activated malate transporter DUF3592 PF12158.3 KKK20526.1 - 3 7.6 5.5 0.56 9.9 0.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3592) Aa_trans PF01490.13 KKK20527.1 - 1.2e-30 106.3 30.8 2.5e-30 105.2 21.4 1.4 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein S1 PF00575.18 KKK20536.1 - 3.8e-76 251.1 26.1 1.7e-14 53.6 0.5 12.0 12 0 0 12 12 12 11 S1 RNA binding domain TPR_16 PF13432.1 KKK20536.1 - 2.9e-08 34.1 0.0 0.012 16.2 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 KKK20536.1 - 2.7e-07 30.8 0.2 0.11 12.8 0.1 3.8 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 KKK20536.1 - 1.1e-06 28.7 0.3 0.78 10.5 0.3 4.9 2 2 3 5 5 5 1 Tetratricopeptide repeat Suf PF05843.9 KKK20536.1 - 1.3e-05 25.1 0.7 0.068 12.8 0.1 3.5 1 1 1 2 2 2 2 Suppressor of forked protein (Suf) TPR_11 PF13414.1 KKK20536.1 - 0.0018 17.8 0.1 2.9 7.5 0.0 2.6 2 0 0 2 2 2 2 TPR repeat PPR PF01535.15 KKK20536.1 - 0.0068 16.3 0.1 2.2 8.4 0.0 3.4 3 0 0 3 3 3 1 PPR repeat TPR_12 PF13424.1 KKK20536.1 - 0.0086 15.9 0.3 3.7 7.5 0.1 3.2 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 KKK20536.1 - 0.02 14.6 3.5 0.9 9.4 0.0 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.12 KKK20536.1 - 0.079 12.9 1.3 6.8 6.8 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_15 PF13429.1 KKK20536.1 - 0.084 11.9 0.5 0.29 10.1 0.3 1.8 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_6 PF13174.1 KKK20536.1 - 0.18 12.3 2.0 1.2e+02 3.5 0.1 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat SDA1 PF05285.7 KKK20536.1 - 1 8.5 26.5 0.03 13.6 10.6 2.7 2 0 0 2 2 2 0 SDA1 WD40 PF00400.27 KKK20537.1 - 4.9e-23 80.1 2.6 3.6e-05 23.4 0.0 5.8 5 0 0 5 5 5 5 WD domain, G-beta repeat Cpn60_TCP1 PF00118.19 KKK20538.1 - 1.9e-142 475.3 14.5 2.1e-142 475.1 10.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family ProRS-C_1 PF09180.6 KKK20539.1 - 1.6e-22 79.2 1.5 3.8e-22 77.9 1.1 1.7 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.20 KKK20539.1 - 4.2e-22 78.5 0.1 6.2e-22 77.9 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 KKK20539.1 - 1.7e-11 43.9 0.0 3.9e-11 42.7 0.0 1.7 1 0 0 1 1 1 1 Anticodon binding domain DUF1497 PF07384.6 KKK20539.1 - 0.077 13.1 0.0 0.21 11.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1497) STAG PF08514.6 KKK20540.1 - 6.3e-38 129.1 0.5 1.6e-37 127.8 0.4 1.7 1 0 0 1 1 1 1 STAG domain HEAT_2 PF13646.1 KKK20540.1 - 7.5e-05 22.9 1.0 0.06 13.6 0.0 4.3 4 1 0 4 4 4 1 HEAT repeats FlgM PF04316.8 KKK20540.1 - 0.00011 22.0 3.0 0.0019 18.1 1.4 3.1 3 0 0 3 3 3 1 Anti-sigma-28 factor, FlgM HEAT PF02985.17 KKK20540.1 - 0.0081 16.1 0.0 47 4.4 0.0 5.0 5 0 0 5 5 5 0 HEAT repeat Nop14 PF04147.7 KKK20540.1 - 1.8 6.3 35.0 0.13 10.1 9.0 2.9 3 0 0 3 3 3 0 Nop14-like family Daxx PF03344.10 KKK20540.1 - 5.1 5.4 32.4 0.15 10.5 5.0 2.6 2 0 0 2 2 2 0 Daxx Family UreD PF01774.12 KKK20541.1 - 5.9e-51 172.9 0.0 8.2e-51 172.4 0.0 1.2 1 0 0 1 1 1 1 UreD urease accessory protein Tir_receptor_N PF07490.6 KKK20541.1 - 0.089 12.3 1.4 0.16 11.5 0.8 1.5 1 1 0 1 1 1 0 Translocated intimin receptor (Tir) N-terminus zf-C4H2 PF10146.4 KKK20541.1 - 0.19 11.6 0.7 0.36 10.8 0.3 1.5 2 0 0 2 2 2 0 Zinc finger-containing protein Pro_dh PF01619.13 KKK20556.1 - 3.2e-36 124.8 0.0 5e-36 124.2 0.0 1.4 1 1 0 1 1 1 1 Proline dehydrogenase AAA_assoc PF14363.1 KKK20556.1 - 0.0055 16.7 0.0 0.013 15.5 0.0 1.6 1 0 0 1 1 1 1 Domain associated at C-terminal with AAA IMS_C PF11799.3 KKK20556.1 - 0.089 12.7 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 impB/mucB/samB family C-terminal domain TrmE_N PF10396.4 KKK20556.1 - 0.089 12.7 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 GTP-binding protein TrmE N-terminus Glyco_hydro_65m PF03632.10 KKK20557.1 - 6.3e-95 317.9 1.0 3e-94 315.7 0.7 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 65 central catalytic domain Glyco_hydro_65N PF03636.10 KKK20557.1 - 3.6e-55 187.0 0.0 6e-55 186.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Glyco_hydro_65C PF03633.10 KKK20557.1 - 1.4e-06 28.2 0.1 2.9e-06 27.2 0.1 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, C-terminal domain Catalase PF00199.14 KKK20558.1 - 1.2e-157 524.5 0.5 1.5e-157 524.1 0.4 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 KKK20558.1 - 8.3e-17 60.8 0.0 2e-16 59.6 0.0 1.7 1 0 0 1 1 1 1 Catalase-related immune-responsive Hs1pro-1_C PF07014.7 KKK20558.1 - 0.17 11.1 0.0 0.3 10.3 0.0 1.3 1 0 0 1 1 1 0 Hs1pro-1 protein C-terminus Kin17_mid PF10357.4 KKK20559.1 - 1.2e-49 167.1 2.4 1.2e-49 167.1 1.6 2.0 3 0 0 3 3 3 1 Domain of Kin17 curved DNA-binding protein zf-C2H2_jaz PF12171.3 KKK20559.1 - 0.0001 22.2 1.5 0.00022 21.2 1.0 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KKK20559.1 - 0.0015 18.6 3.7 0.0022 18.1 1.5 2.1 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 KKK20559.1 - 0.34 11.0 5.5 0.11 12.5 0.4 2.3 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Menin PF05053.8 KKK20559.1 - 0.82 7.7 8.0 1 7.4 5.6 1.1 1 0 0 1 1 1 0 Menin Actin PF00022.14 KKK20560.1 - 3.4e-24 84.9 0.0 2.2e-22 79.0 0.0 2.5 2 1 0 2 2 2 2 Actin TT_ORF2 PF02957.10 KKK20560.1 - 0.19 12.4 11.2 0.18 12.5 0.3 2.9 2 0 0 2 2 2 0 TT viral ORF2 CBFD_NFYB_HMF PF00808.18 KKK20561.1 - 2.6e-17 62.6 0.2 2.6e-17 62.6 0.1 1.5 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 KKK20561.1 - 4.6e-05 23.4 0.0 6.9e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.8 KKK20561.1 - 0.008 15.8 0.0 0.013 15.2 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated Mrr_N PF14338.1 KKK20561.1 - 0.11 12.5 0.8 0.18 11.9 0.2 1.6 2 0 0 2 2 2 0 Mrr N-terminal domain YolD PF08863.5 KKK20561.1 - 1.6 8.6 4.1 3.2 7.6 2.9 1.5 1 0 0 1 1 1 0 YolD-like protein adh_short PF00106.20 KKK20562.1 - 1.9e-28 99.4 0.5 2.8e-28 98.9 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KKK20562.1 - 6e-12 45.8 0.0 8.3e-12 45.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KKK20562.1 - 4.1e-10 39.6 0.3 8.3e-10 38.6 0.2 1.4 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KKK20562.1 - 9.2e-05 22.5 0.1 0.00014 21.8 0.1 1.7 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KKK20562.1 - 0.0013 18.1 0.0 0.026 13.9 0.0 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.13 KKK20562.1 - 0.0067 16.4 0.0 0.013 15.5 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain NmrA PF05368.8 KKK20562.1 - 0.029 13.6 0.2 0.053 12.7 0.1 1.4 2 0 0 2 2 2 0 NmrA-like family Shikimate_DH PF01488.15 KKK20562.1 - 0.05 13.6 0.0 0.098 12.7 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 3Beta_HSD PF01073.14 KKK20562.1 - 0.09 11.4 0.0 0.15 10.7 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Eno-Rase_NADH_b PF12242.3 KKK20562.1 - 0.11 12.3 0.2 0.24 11.1 0.1 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DAO PF01266.19 KKK20563.1 - 7.2e-32 110.6 0.0 1.1e-31 110.0 0.0 1.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KKK20563.1 - 0.0023 17.8 0.1 0.0053 16.7 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KKK20563.1 - 0.023 15.1 0.0 0.073 13.4 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KKK20563.1 - 0.092 12.5 0.0 0.24 11.1 0.0 1.7 1 0 0 1 1 1 0 FAD-NAD(P)-binding SMC_Nse1 PF07574.8 KKK20564.1 - 2.2e-35 122.1 0.0 3.7e-35 121.3 0.0 1.4 1 0 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex zf-CCCH PF00642.19 KKK20564.1 - 1.4e-07 30.9 17.3 8.5e-07 28.5 1.5 3.0 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_5 PF13893.1 KKK20564.1 - 3.9e-05 23.4 0.0 0.0001 22.0 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KKK20564.1 - 0.0019 17.8 0.0 0.0052 16.3 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pkinase PF00069.20 KKK20565.1 - 0.00023 20.3 0.0 0.0016 17.6 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain AsmA_1 PF13109.1 KKK20565.1 - 0.0087 15.3 0.0 0.013 14.8 0.0 1.2 1 0 0 1 1 1 1 AsmA-like C-terminal region CLASP_N PF12348.3 KKK20576.1 - 3.4e-154 510.7 2.0 1.7e-86 289.2 0.0 2.2 2 0 0 2 2 2 2 CLASP N terminal HEAT PF02985.17 KKK20576.1 - 3.6e-10 39.0 0.2 0.005 16.8 0.0 5.5 5 0 0 5 5 5 2 HEAT repeat HEAT_2 PF13646.1 KKK20576.1 - 1.9e-07 31.2 1.8 0.21 11.9 0.1 4.6 3 1 1 4 4 4 2 HEAT repeats HEAT_EZ PF13513.1 KKK20576.1 - 8.8e-05 22.8 0.3 0.7 10.4 0.0 4.2 3 0 0 3 3 3 2 HEAT-like repeat Cnd1 PF12717.2 KKK20576.1 - 0.00015 21.6 0.0 0.0049 16.7 0.0 2.7 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.15 KKK20576.1 - 0.046 12.0 0.5 0.5 8.6 0.1 2.5 2 1 1 3 3 3 0 Adaptin N terminal region RhoGAP PF00620.22 KKK20577.1 - 6.1e-48 162.2 0.0 2e-47 160.6 0.0 1.9 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.17 KKK20577.1 - 1.7e-13 50.4 20.5 8e-09 35.4 3.0 2.4 2 0 0 2 2 2 2 LIM domain TMF_TATA_bd PF12325.3 KKK20577.1 - 0.2 11.4 19.1 2.6 7.7 3.6 3.7 2 1 0 3 3 3 0 TATA element modulatory factor 1 TATA binding Ribonuclease_3 PF00636.21 KKK20578.1 - 1.6e-08 34.9 0.0 9.6e-08 32.4 0.0 2.2 2 1 0 2 2 2 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 KKK20578.1 - 3.7e-08 33.3 0.0 0.001 19.0 0.0 2.3 2 0 0 2 2 2 2 Ribonuclease-III-like dsrm PF00035.20 KKK20578.1 - 1.1e-06 29.1 0.0 2.2e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 Double-stranded RNA binding motif DUF2333 PF10095.4 KKK20578.1 - 0.17 10.5 0.4 0.25 9.9 0.2 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2333) BSP PF04450.7 KKK20579.1 - 5.2e-71 238.3 0.0 7.3e-71 237.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase of plants and bacteria Peptidase_MA_2 PF13485.1 KKK20579.1 - 0.00082 19.4 0.0 0.0014 18.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase MA superfamily SprT-like PF10263.4 KKK20579.1 - 0.014 15.0 0.0 0.025 14.2 0.0 1.4 1 0 0 1 1 1 0 SprT-like family CAP_N PF01213.14 KKK20580.1 - 1.5e-83 280.6 15.4 2.7e-82 276.5 10.7 2.0 1 1 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.6 KKK20580.1 - 2.6e-54 182.8 0.6 3.8e-54 182.3 0.4 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.7 KKK20580.1 - 0.0057 16.0 4.3 0.21 11.0 3.0 2.2 1 1 1 2 2 2 2 Tubulin binding cofactor C PfkB PF00294.19 KKK20581.1 - 1.9e-14 53.4 0.0 1.2e-13 50.8 0.0 1.9 1 1 0 1 1 1 1 pfkB family carbohydrate kinase RRM_5 PF13893.1 KKK20583.1 - 0.032 14.0 0.0 0.058 13.2 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KKK20583.1 - 0.048 13.6 0.0 0.093 12.7 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) FLO_LFY PF01698.11 KKK20583.1 - 3.9 6.2 8.4 0.48 9.2 2.0 2.0 2 0 0 2 2 2 0 Floricaula / Leafy protein CDC45 PF02724.9 KKK20583.1 - 7.4 4.4 15.5 0.14 10.2 5.6 1.7 2 0 0 2 2 2 0 CDC45-like protein LicD PF04991.8 KKK20584.1 - 1.9e-37 129.4 5.9 1.7e-36 126.2 4.1 2.1 1 1 0 1 1 1 1 LicD family UvrD-helicase PF00580.16 KKK20584.1 - 0.051 12.8 0.1 0.074 12.3 0.1 1.3 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain HSP70 PF00012.15 KKK20585.1 - 1.2e-148 495.7 1.9 1.2e-148 495.7 1.3 2.2 1 1 1 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.8 KKK20585.1 - 4.1e-11 42.0 0.0 7.7e-11 41.1 0.0 1.3 1 0 0 1 1 1 1 MreB/Mbl protein Peptidase_M22 PF00814.20 KKK20585.1 - 0.025 14.0 0.2 4.9 6.5 0.0 2.4 2 0 0 2 2 2 0 Glycoprotease family V_ATPase_I PF01496.14 KKK20585.1 - 0.062 11.1 12.0 0.094 10.5 8.3 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FGGY_C PF02782.11 KKK20585.1 - 0.075 12.6 0.1 0.35 10.4 0.0 2.2 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.1 KKK20585.1 - 0.092 12.5 3.4 1.3 8.8 0.0 3.7 3 1 0 3 3 3 0 Cell division protein FtsA Metal_resist PF13801.1 KKK20585.1 - 2.4 8.1 7.7 0.67 9.9 0.1 2.4 2 0 0 2 2 2 0 Heavy-metal resistance APH PF01636.18 KKK20586.1 - 1.9e-05 24.5 0.0 2.2e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Thiolase_N PF00108.18 KKK20587.1 - 1.7e-73 246.8 0.1 2.7e-73 246.2 0.1 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 KKK20587.1 - 4.9e-40 135.7 0.4 4.9e-40 135.7 0.3 1.8 2 0 0 2 2 2 1 Thiolase, C-terminal domain ACP_syn_III PF08545.5 KKK20587.1 - 0.0031 17.1 0.1 0.11 12.1 0.0 2.5 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.21 KKK20587.1 - 0.009 15.5 1.5 0.027 13.9 0.7 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III_C PF08541.5 KKK20587.1 - 0.11 12.5 0.0 0.36 10.8 0.0 1.9 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal DASH_Ask1 PF08655.5 KKK20589.1 - 7.6e-34 115.3 0.1 1.6e-33 114.3 0.0 1.6 1 0 0 1 1 1 1 DASH complex subunit Ask1 WLM PF08325.5 KKK20590.1 - 2e-44 151.7 0.2 6.6e-44 149.9 0.0 1.7 2 0 0 2 2 2 1 WLM domain DUF45 PF01863.12 KKK20590.1 - 4.2e-05 23.4 0.6 7.5e-05 22.6 0.4 1.4 1 0 0 1 1 1 1 Protein of unknown function DUF45 SprT-like PF10263.4 KKK20590.1 - 0.00061 19.4 0.5 0.001 18.7 0.4 1.4 1 0 0 1 1 1 1 SprT-like family Peptidase_MA_2 PF13485.1 KKK20590.1 - 0.079 13.0 0.5 0.16 12.0 0.0 1.7 2 0 0 2 2 2 0 Peptidase MA superfamily DUF955 PF06114.8 KKK20590.1 - 0.096 12.4 0.1 0.32 10.7 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF955) LIM PF00412.17 KKK20595.1 - 8.1e-14 51.4 15.8 5.9e-08 32.6 3.3 2.8 2 1 0 2 2 2 2 LIM domain Methyltransf_4 PF02390.12 KKK20596.1 - 0.00053 19.0 0.0 0.00079 18.5 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Ribonuc_L-PSP PF01042.16 KKK20597.1 - 9.1e-24 83.5 0.0 1.1e-23 83.3 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Cu-oxidase_2 PF07731.9 KKK20598.1 - 1.9e-47 160.2 11.4 2.1e-42 143.8 1.9 3.8 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 KKK20598.1 - 5.2e-41 139.0 6.6 3.9e-38 129.8 1.1 3.5 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 KKK20598.1 - 5.4e-40 136.8 3.9 7.4e-34 116.9 0.2 3.6 3 0 0 3 3 3 3 Multicopper oxidase COX2 PF00116.15 KKK20598.1 - 0.0027 17.5 3.1 0.68 9.7 0.1 4.2 5 0 0 5 5 5 1 Cytochrome C oxidase subunit II, periplasmic domain Cupredoxin_1 PF13473.1 KKK20598.1 - 0.0046 16.8 0.0 6.2 6.7 0.0 3.7 4 0 0 4 4 4 1 Cupredoxin-like domain Self-incomp_S1 PF05938.6 KKK20598.1 - 0.11 12.5 0.1 7 6.8 0.1 2.3 2 0 0 2 2 2 0 Plant self-incompatibility protein S1 DUF924 PF06041.6 KKK20599.1 - 1.5e-46 158.5 5.9 2.9e-45 154.3 4.1 2.2 1 1 0 1 1 1 1 Bacterial protein of unknown function (DUF924) RNA_pol_3_Rpc31 PF11705.3 KKK20599.1 - 0.82 9.5 8.1 3.1 7.6 5.1 2.0 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 Fe_hyd_lg_C PF02906.9 KKK20601.1 - 2.1e-63 214.2 0.0 3.6e-63 213.4 0.0 1.4 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain FTR1 PF03239.9 KKK20602.1 - 1.6e-83 280.2 8.4 2e-83 279.8 5.8 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family DUF3112 PF11309.3 KKK20602.1 - 0.005 16.6 0.7 0.0099 15.6 0.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3112) DUF3180 PF11377.3 KKK20602.1 - 6.1 6.7 8.8 1.7 8.4 0.4 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3180) Sec7_N PF12783.2 KKK20603.1 - 1.3e-43 148.3 3.2 5e-43 146.4 0.1 3.2 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DIOX_N PF14226.1 KKK20604.1 - 1.3e-25 90.1 0.0 2.2e-25 89.4 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KKK20604.1 - 5.5e-19 68.3 0.0 1.1e-18 67.2 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily TMEM51 PF15345.1 KKK20605.1 - 0.028 14.0 0.4 0.15 11.7 0.0 2.2 1 1 1 2 2 2 0 Transmembrane protein 51 DUF4131 PF13567.1 KKK20605.1 - 0.096 12.0 0.0 0.19 11.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) RWD PF05773.17 KKK20607.1 - 7.1e-24 83.8 1.0 1.4e-23 82.9 0.7 1.5 1 0 0 1 1 1 1 RWD domain UQ_con PF00179.21 KKK20607.1 - 0.42 10.0 2.4 0.9 8.9 0.5 2.2 1 1 1 2 2 2 0 Ubiquitin-conjugating enzyme KBP_C PF12309.3 KKK20607.1 - 0.55 9.1 7.3 0.72 8.7 5.0 1.1 1 0 0 1 1 1 0 KIF-1 binding protein C terminal Cyclin_N PF00134.18 KKK20608.1 - 1.3e-45 154.0 0.1 1.5e-44 150.6 0.0 2.3 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 KKK20608.1 - 1.2e-33 115.5 0.0 3.3e-33 114.1 0.0 1.8 1 0 0 1 1 1 1 Cyclin, C-terminal domain UQ_con PF00179.21 KKK20609.1 - 2.3e-16 59.4 0.0 2.6e-16 59.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Abhydrolase_6 PF12697.2 KKK20610.1 - 2e-29 103.1 0.5 3.4e-29 102.3 0.4 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KKK20610.1 - 2.1e-07 30.8 0.0 4.9e-07 29.6 0.0 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KKK20610.1 - 2.6e-05 23.8 0.0 4.2e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.8 KKK20610.1 - 0.031 13.8 0.0 0.053 13.0 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Ceramidase PF05875.7 KKK20611.1 - 1e-82 277.2 7.0 3.5e-57 193.5 1.3 2.0 1 1 1 2 2 2 2 Ceramidase Mito_carr PF00153.22 KKK20612.1 - 4.7e-55 183.2 2.7 4.5e-19 67.9 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein ESCRT-II PF05871.7 KKK20613.1 - 9.9e-50 168.0 0.7 1.4e-49 167.6 0.5 1.2 1 0 0 1 1 1 1 ESCRT-II complex subunit BRCT PF00533.21 KKK20614.1 - 9.5e-29 99.3 0.0 2.1e-06 27.7 0.0 6.5 6 0 0 6 6 6 6 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 KKK20614.1 - 2.7e-26 91.2 0.2 4.8e-19 67.9 0.2 5.1 4 1 0 4 4 4 3 twin BRCT domain Prefoldin_2 PF01920.15 KKK20615.1 - 4.7e-09 35.9 0.3 6.6e-09 35.4 0.2 1.3 1 1 0 1 1 1 1 Prefoldin subunit Ribosomal_L10 PF00466.15 KKK20616.1 - 0.073 13.0 0.0 0.66 9.9 0.0 2.4 1 1 0 1 1 1 0 Ribosomal protein L10 Glycos_transf_3 PF00591.16 KKK20617.1 - 2.3e-48 164.7 0.0 2.4e-45 154.9 0.0 3.2 1 1 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.12 KKK20617.1 - 7.1e-07 28.7 0.5 1.4e-06 27.7 0.3 1.6 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain DNA_RNApol_7kD PF03604.8 KKK20618.1 - 2.8e-17 61.8 6.2 3.5e-17 61.5 4.3 1.1 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit DUF2197 PF09963.4 KKK20618.1 - 9.8e-05 22.2 0.6 0.02 14.8 0.0 2.1 1 1 1 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2197) DZR PF12773.2 KKK20618.1 - 0.0019 17.9 0.3 0.0027 17.4 0.2 1.2 1 0 0 1 1 1 1 Double zinc ribbon HypA PF01155.14 KKK20618.1 - 0.012 15.3 0.3 0.014 15.0 0.2 1.1 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family PhnA_Zn_Ribbon PF08274.7 KKK20618.1 - 0.014 15.1 0.2 0.021 14.6 0.1 1.3 1 0 0 1 1 1 0 PhnA Zinc-Ribbon DUF2318 PF10080.4 KKK20618.1 - 0.017 14.8 0.2 0.021 14.5 0.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) TFIIS_C PF01096.13 KKK20618.1 - 0.019 14.5 0.3 3 7.5 0.2 2.3 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) A2L_zn_ribbon PF08792.5 KKK20618.1 - 0.023 14.1 2.4 0.19 11.2 0.1 2.3 2 0 0 2 2 2 0 A2L zinc ribbon domain Zn-ribbon_8 PF09723.5 KKK20618.1 - 0.026 14.4 0.6 0.046 13.6 0.4 1.4 1 0 0 1 1 1 0 Zinc ribbon domain Prok-RING_1 PF14446.1 KKK20618.1 - 0.053 13.2 0.6 0.073 12.8 0.4 1.2 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 GFA PF04828.9 KKK20618.1 - 0.075 12.9 0.9 3.3 7.7 0.1 2.1 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme OrfB_Zn_ribbon PF07282.6 KKK20618.1 - 0.27 10.9 1.9 0.39 10.3 1.3 1.2 1 0 0 1 1 1 0 Putative transposase DNA-binding domain RRN7 PF11781.3 KKK20618.1 - 0.28 10.7 4.8 0.46 10.0 0.1 2.4 2 1 1 3 3 3 0 RNA polymerase I-specific transcription initiation factor Rrn7 DUF951 PF06107.6 KKK20618.1 - 0.29 10.6 2.4 1.2 8.7 0.3 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF951) zf-C4_Topoisom PF01396.14 KKK20618.1 - 0.71 9.4 4.0 11 5.5 0.2 2.1 1 1 1 2 2 2 0 Topoisomerase DNA binding C4 zinc finger Zn_Tnp_IS1595 PF12760.2 KKK20618.1 - 1 9.2 4.1 1.3 8.8 0.4 1.8 1 1 1 2 2 2 0 Transposase zinc-ribbon domain Zn_ribbon_recom PF13408.1 KKK20618.1 - 1.1 9.5 5.7 3.2 8.0 0.9 2.1 1 1 1 2 2 2 0 Recombinase zinc beta ribbon domain zinc_ribbon_4 PF13717.1 KKK20618.1 - 2 8.1 4.3 4.1 7.1 2.2 2.0 1 1 0 1 1 1 0 zinc-ribbon domain UPF0547 PF10571.4 KKK20618.1 - 3.8 7.2 5.1 19 5.0 3.8 1.9 1 1 1 2 2 2 0 Uncharacterised protein family UPF0547 DUF1295 PF06966.7 KKK20619.1 - 7e-10 38.5 0.0 1.1e-09 38.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.11 KKK20619.1 - 4.7e-05 23.1 0.0 0.0001 22.1 0.0 1.5 1 1 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase SKI PF01202.17 KKK20620.1 - 2.7e-11 43.6 0.0 6.1e-11 42.4 0.0 1.6 1 1 0 1 1 1 1 Shikimate kinase AAA_33 PF13671.1 KKK20620.1 - 3.6e-10 39.8 0.0 5e-10 39.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KKK20620.1 - 7.8e-09 36.3 0.0 1.2e-08 35.7 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KKK20620.1 - 3.7e-08 33.7 0.0 1.4e-07 31.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KKK20620.1 - 0.0014 18.7 0.0 0.002 18.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 KKK20620.1 - 0.008 15.6 0.0 0.042 13.3 0.0 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain CoaE PF01121.15 KKK20620.1 - 0.039 13.3 0.0 0.077 12.3 0.0 1.4 1 0 0 1 1 1 0 Dephospho-CoA kinase DUF2338 PF10100.4 KKK20620.1 - 0.04 12.2 0.0 0.05 11.9 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2338) Rad17 PF03215.10 KKK20620.1 - 0.069 11.8 0.0 0.1 11.2 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein APS_kinase PF01583.15 KKK20620.1 - 0.072 12.7 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase Zeta_toxin PF06414.7 KKK20620.1 - 0.08 12.0 0.0 0.13 11.3 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin RNA_helicase PF00910.17 KKK20620.1 - 0.09 12.9 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_19 PF13245.1 KKK20620.1 - 0.09 12.5 0.0 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_16 PF13191.1 KKK20620.1 - 0.1 12.5 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain IPPT PF01715.12 KKK20620.1 - 0.1 11.5 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 IPP transferase DUF2075 PF09848.4 KKK20620.1 - 0.11 11.4 0.0 0.2 10.6 0.0 1.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA PF00004.24 KKK20620.1 - 0.11 12.6 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Vps26 PF03643.10 KKK20621.1 - 9.5e-130 431.2 0.5 1.1e-129 431.0 0.3 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.24 KKK20621.1 - 0.00039 20.2 0.2 0.94 9.2 0.0 3.0 3 0 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain DUF432 PF04254.8 KKK20621.1 - 0.026 14.4 0.0 0.051 13.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF432) Arrestin_C PF02752.17 KKK20621.1 - 0.039 14.0 0.2 0.21 11.7 0.1 2.3 1 1 1 2 2 2 0 Arrestin (or S-antigen), C-terminal domain 2-oxoacid_dh PF00198.18 KKK20622.1 - 7.1e-77 257.7 0.0 1e-76 257.2 0.0 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 KKK20622.1 - 2.5e-13 49.4 0.0 4.8e-13 48.5 0.0 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 KKK20622.1 - 3.4e-12 45.8 0.2 7.7e-12 44.6 0.2 1.6 1 0 0 1 1 1 1 e3 binding domain PI-PLC-X PF00388.14 KKK20623.1 - 1.6e-11 43.7 0.0 2.5e-11 43.1 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain DUF3435 PF11917.3 KKK20624.1 - 1.5e-130 435.6 0.2 1.7e-107 359.7 0.0 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF3435) DDE_3 PF13358.1 KKK20624.1 - 0.016 14.9 0.1 0.16 11.6 0.0 2.4 2 0 0 2 2 2 0 DDE superfamily endonuclease zf-C2H2 PF00096.21 KKK20624.1 - 0.58 10.6 4.3 1.5 9.2 3.0 1.8 1 0 0 1 1 1 0 Zinc finger, C2H2 type HNH_2 PF13391.1 KKK20625.1 - 6.1e-13 48.3 0.1 1.9e-12 46.7 0.0 1.9 2 0 0 2 2 2 1 HNH endonuclease Granulin PF00396.13 KKK20626.1 - 0.84 9.7 13.8 8.6 6.5 6.7 3.0 2 1 0 2 2 2 0 Granulin APH PF01636.18 KKK20627.1 - 3.8e-15 56.2 0.0 8.9e-15 55.0 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 KKK20627.1 - 0.12 11.5 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase Choline_kinase PF01633.15 KKK20627.1 - 0.13 11.8 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase PHD PF00628.24 KKK20628.1 - 3.9e-08 32.8 9.3 3.9e-08 32.8 6.4 1.9 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.1 KKK20628.1 - 0.097 12.0 9.0 0.047 13.0 3.8 2.1 2 0 0 2 2 2 0 PHD-finger Rcd1 PF04078.8 KKK20629.1 - 3e-131 436.0 2.8 3.7e-131 435.7 2.0 1.1 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like Med15 PF09606.5 KKK20629.1 - 1.7 6.7 24.6 2.1 6.4 17.0 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Complex1_LYR_1 PF13232.1 KKK20630.1 - 1.2e-17 63.8 0.1 1.2e-17 63.8 0.1 2.7 3 0 0 3 3 3 1 Complex1_LYR-like Complex1_LYR PF05347.10 KKK20630.1 - 7.3e-17 60.9 2.1 9.3e-17 60.5 0.1 2.2 2 1 1 3 3 3 1 Complex 1 protein (LYR family) SIR2 PF02146.12 KKK20631.1 - 1.4e-60 204.0 0.0 2.1e-60 203.5 0.0 1.3 1 0 0 1 1 1 1 Sir2 family DUF592 PF04574.8 KKK20631.1 - 0.0003 20.3 0.0 0.0006 19.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF592) TPP_enzyme_M PF00205.17 KKK20631.1 - 0.033 13.9 0.0 1.6 8.5 0.0 2.4 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain TPR_16 PF13432.1 KKK20632.1 - 3.2e-12 46.7 3.6 5.6e-06 26.8 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 KKK20632.1 - 3.7e-12 46.0 0.1 2.1e-06 27.5 0.0 3.5 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 KKK20632.1 - 4.6e-12 45.4 1.0 2.1e-05 24.0 0.0 4.3 3 1 1 4 4 4 3 TPR repeat TPR_19 PF14559.1 KKK20632.1 - 2.5e-11 43.7 6.7 4.4e-05 23.7 0.2 3.8 2 1 2 4 4 4 4 Tetratricopeptide repeat TPR_14 PF13428.1 KKK20632.1 - 2e-09 37.2 7.6 0.093 13.4 0.2 5.0 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.12 KKK20632.1 - 4.2e-08 32.5 4.2 0.009 15.8 0.0 5.7 6 0 0 6 6 5 2 Tetratricopeptide repeat Apc3 PF12895.2 KKK20632.1 - 2e-06 27.8 0.0 0.015 15.4 0.0 2.7 2 0 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 KKK20632.1 - 3.5e-06 26.3 0.1 0.028 14.1 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.1 KKK20632.1 - 3.7e-06 26.7 7.1 0.029 14.2 0.4 4.1 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.1 KKK20632.1 - 8.9e-05 22.2 5.5 0.52 10.3 0.1 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_15 PF13429.1 KKK20632.1 - 0.00014 21.0 2.0 0.0088 15.1 0.1 3.5 2 2 1 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 KKK20632.1 - 0.00025 21.0 0.2 1.3 9.3 0.0 4.8 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 KKK20632.1 - 0.00031 20.2 3.1 0.049 13.2 0.0 4.4 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_6 PF13174.1 KKK20632.1 - 0.00049 20.3 4.8 0.26 11.8 0.0 5.2 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_7 PF13176.1 KKK20632.1 - 0.00076 19.1 0.2 2 8.4 0.0 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat YfiO PF13525.1 KKK20632.1 - 0.12 11.8 0.1 7.5 5.9 0.0 2.5 3 0 0 3 3 3 0 Outer membrane lipoprotein TPR_21 PF09976.4 KKK20632.1 - 0.14 12.0 1.9 0.79 9.6 0.1 2.7 2 1 1 3 3 3 0 Tetratricopeptide repeat Vps39_1 PF10366.4 KKK20632.1 - 0.58 10.2 4.0 0.31 11.0 0.2 2.4 3 0 0 3 3 3 0 Vacuolar sorting protein 39 domain 1 DUF2457 PF10446.4 KKK20632.1 - 4.3 5.9 10.4 7.4 5.1 7.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Ribosomal_L2_C PF03947.13 KKK20633.1 - 3.1e-47 159.6 1.0 5.3e-33 113.5 0.5 2.4 1 1 1 2 2 2 2 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 KKK20633.1 - 1.8e-26 91.8 0.2 4.7e-26 90.5 0.1 1.8 2 0 0 2 2 2 1 Ribosomal Proteins L2, RNA binding domain PAS PF00989.19 KKK20633.1 - 0.1 12.3 0.1 0.2 11.4 0.1 1.4 1 0 0 1 1 1 0 PAS fold Fungal_trans PF04082.13 KKK20634.1 - 8.2e-21 74.0 0.0 1.9e-20 72.8 0.0 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK20634.1 - 1.1e-09 38.0 12.0 2.1e-09 37.1 8.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF655 PF04919.7 KKK20634.1 - 0.21 11.2 0.0 0.37 10.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF655) UPF0020 PF01170.13 KKK20635.1 - 7.2e-09 35.4 0.1 2e-06 27.5 0.0 2.2 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_26 PF13659.1 KKK20635.1 - 1.1e-06 28.6 0.0 2.7e-06 27.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain N6_Mtase PF02384.11 KKK20635.1 - 0.2 10.7 0.0 9.5 5.1 0.0 2.1 1 1 1 2 2 2 0 N-6 DNA Methylase Ribonuc_P_40 PF08584.6 KKK20636.1 - 7e-94 313.9 0.0 8.5e-94 313.7 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease P 40kDa (Rpp40) subunit WD40 PF00400.27 KKK20637.1 - 3.2e-35 118.7 16.3 2.4e-10 39.8 0.0 7.1 7 0 0 7 7 7 4 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 KKK20637.1 - 2e-08 32.9 0.0 2.1e-05 23.0 0.0 2.1 2 0 0 2 2 2 2 Cytochrome D1 heme domain eIF2A PF08662.6 KKK20637.1 - 1e-05 25.3 0.0 0.091 12.4 0.0 2.8 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 KKK20637.1 - 0.00018 19.8 0.3 0.1 10.7 0.1 2.1 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Apc4_WD40 PF12894.2 KKK20637.1 - 0.018 14.5 0.0 0.055 12.9 0.0 1.9 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain TFIIIC_delta PF12657.2 KKK20637.1 - 0.043 13.5 2.7 4 7.1 0.0 3.9 4 1 1 5 5 5 0 Transcription factor IIIC subunit delta N-term Coatomer_WDAD PF04053.9 KKK20637.1 - 0.11 11.2 0.0 0.44 9.2 0.0 1.9 2 0 0 2 2 2 0 Coatomer WD associated region MFS_1 PF07690.11 KKK20638.1 - 7.2e-27 94.0 78.2 5.9e-23 81.1 33.2 1.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Methyltransf_4 PF02390.12 KKK20639.1 - 2.8e-37 127.6 0.0 1.9e-36 124.9 0.0 1.9 2 0 0 2 2 2 1 Putative methyltransferase ESSS PF10183.4 KKK20640.1 - 2.5e-30 104.9 0.0 2.9e-30 104.7 0.0 1.1 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) DUF3961 PF13106.1 KKK20640.1 - 0.34 10.5 2.1 0.53 9.8 1.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3961) Dna2 PF08696.6 KKK20641.1 - 2.5e-71 239.3 1.4 4.4e-71 238.4 1.0 1.4 1 0 0 1 1 1 1 DNA replication factor Dna2 AAA_12 PF13087.1 KKK20641.1 - 5.6e-52 176.0 0.0 9.7e-52 175.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KKK20641.1 - 7.1e-42 143.5 0.3 1.6e-21 77.0 0.0 2.7 1 1 1 2 2 2 2 AAA domain AAA_30 PF13604.1 KKK20641.1 - 1.3e-13 50.9 0.0 2.5e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KKK20641.1 - 1.3e-11 44.0 0.1 3.2e-11 42.8 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain PDDEXK_1 PF12705.2 KKK20641.1 - 5e-11 42.4 0.0 1.2e-10 41.2 0.0 1.5 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily Cas_Cas4 PF01930.12 KKK20641.1 - 3.4e-08 33.5 0.1 1e-07 31.9 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function DUF83 Viral_helicase1 PF01443.13 KKK20641.1 - 3.6e-07 29.9 0.1 0.35 10.3 0.0 3.6 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.9 KKK20641.1 - 6.8e-05 22.5 0.0 0.00023 20.8 0.0 2.0 1 0 0 1 1 1 1 Helicase UvrD-helicase PF00580.16 KKK20641.1 - 0.00063 19.1 1.8 0.0012 18.2 0.1 2.2 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain CbiA PF01656.18 KKK20641.1 - 0.00075 18.9 0.0 0.0019 17.6 0.0 1.6 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MobB PF03205.9 KKK20641.1 - 0.0011 18.6 0.0 0.0026 17.4 0.0 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B SRP54 PF00448.17 KKK20641.1 - 0.0011 18.4 0.1 0.0022 17.4 0.1 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_16 PF13191.1 KKK20641.1 - 0.0021 18.0 0.0 0.0063 16.5 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain PIF1 PF05970.9 KKK20641.1 - 0.0069 15.3 0.2 0.2 10.5 0.0 2.5 3 0 0 3 3 3 1 PIF1-like helicase DUF2075 PF09848.4 KKK20641.1 - 0.029 13.3 0.0 0.049 12.6 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_25 PF13481.1 KKK20641.1 - 0.035 13.5 0.0 0.092 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 KKK20641.1 - 0.043 14.3 0.0 0.12 12.8 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein DUF87 PF01935.12 KKK20641.1 - 0.045 13.5 0.2 0.14 12.0 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function DUF87 ResIII PF04851.10 KKK20641.1 - 0.062 13.1 0.2 0.19 11.5 0.1 1.9 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_22 PF13401.1 KKK20641.1 - 0.065 13.3 0.1 0.28 11.3 0.0 2.2 1 1 0 1 1 1 0 AAA domain AAA PF00004.24 KKK20641.1 - 0.082 13.1 0.4 0.31 11.2 0.0 2.2 3 0 0 3 3 1 0 ATPase family associated with various cellular activities (AAA) ArgK PF03308.11 KKK20641.1 - 0.096 11.4 0.1 0.24 10.1 0.1 1.6 1 0 0 1 1 1 0 ArgK protein AAA_5 PF07728.9 KKK20641.1 - 0.1 12.3 0.0 0.35 10.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RNB PF00773.14 KKK20642.1 - 5.6e-95 318.3 0.1 1e-94 317.4 0.0 1.4 1 0 0 1 1 1 1 RNB domain PIN_4 PF13638.1 KKK20642.1 - 1.8e-08 34.5 0.3 4.5e-08 33.2 0.2 1.7 1 0 0 1 1 1 1 PIN domain CN_hydrolase PF00795.17 KKK20643.1 - 4.4e-24 84.8 0.0 9e-24 83.8 0.0 1.5 2 0 0 2 2 2 1 Carbon-nitrogen hydrolase APH PF01636.18 KKK20644.1 - 1.7e-19 70.4 0.0 2.3e-19 70.0 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KKK20644.1 - 0.0015 18.1 0.0 0.0032 17.0 0.0 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.17 KKK20644.1 - 0.054 12.8 0.0 0.47 9.7 0.0 2.0 2 0 0 2 2 2 0 RIO1 family EcKinase PF02958.15 KKK20644.1 - 0.081 12.0 0.0 0.32 10.1 0.0 1.8 1 1 1 2 2 2 0 Ecdysteroid kinase Fic PF02661.13 KKK20645.1 - 7.9e-11 42.5 0.3 1.7e-10 41.4 0.2 1.5 1 1 0 1 1 1 1 Fic/DOC family INSIG PF07281.7 KKK20655.1 - 9.7e-86 286.0 0.9 1.2e-85 285.7 0.6 1.1 1 0 0 1 1 1 1 Insulin-induced protein (INSIG) Bromodomain PF00439.20 KKK20656.1 - 2.1e-26 91.6 0.2 4.1e-26 90.7 0.1 1.5 1 0 0 1 1 1 1 Bromodomain Acetyltransf_7 PF13508.1 KKK20656.1 - 1.6e-09 37.8 0.1 3.8e-09 36.5 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KKK20656.1 - 1.6e-08 34.4 0.0 3.5e-08 33.3 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family DEAD PF00270.24 KKK20657.1 - 6e-46 156.0 0.0 5e-45 153.0 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KKK20657.1 - 2.9e-27 94.3 0.1 5.8e-27 93.3 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KKK20657.1 - 0.027 14.3 0.0 0.066 13.0 0.0 1.6 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Peptidase_M16 PF00675.15 KKK20657.1 - 0.11 12.2 0.0 8.9 6.0 0.0 2.4 2 0 0 2 2 2 0 Insulinase (Peptidase family M16) CMS1 PF14617.1 KKK20657.1 - 0.18 10.8 0.1 0.32 10.0 0.1 1.2 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit DUF1253 PF06862.7 KKK20657.1 - 0.25 9.7 0.0 0.45 8.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1253) Ribosomal_S13 PF00416.17 KKK20658.1 - 1.1e-20 74.0 0.0 1.4e-20 73.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 EMP24_GP25L PF01105.19 KKK20659.1 - 1.6e-50 171.3 0.1 1.9e-50 171.1 0.1 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DMAP1 PF05499.7 KKK20660.1 - 0.00057 19.4 7.0 0.0015 18.1 1.9 2.6 2 1 0 2 2 2 1 DNA methyltransferase 1-associated protein 1 (DMAP1) Myb_DNA-bind_6 PF13921.1 KKK20660.1 - 0.06 13.4 0.2 0.49 10.5 0.0 2.3 2 0 0 2 2 2 0 Myb-like DNA-binding domain HATPase_c PF02518.21 KKK20662.1 - 5.5e-20 71.1 0.0 9.9e-20 70.3 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 KKK20662.1 - 1.4e-15 57.3 0.3 0.00027 20.8 0.0 3.6 3 0 0 3 3 3 3 Response regulator receiver domain HisKA PF00512.20 KKK20662.1 - 3.4e-07 30.1 0.1 1.6e-06 27.9 0.0 2.1 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.1 KKK20662.1 - 0.005 16.4 0.0 0.017 14.7 0.0 1.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.1 KKK20662.1 - 0.096 12.4 0.0 0.3 10.8 0.0 1.8 2 0 0 2 2 2 0 Histidine kinase-like ATPase domain Ufd2P_core PF10408.4 KKK20663.1 - 1.1e-202 674.7 8.5 1.3e-202 674.4 5.9 1.1 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.10 KKK20663.1 - 4.8e-27 93.7 3.6 4.9e-27 93.6 0.7 2.5 2 0 0 2 2 2 1 U-box domain Kisspeptin PF15152.1 KKK20663.1 - 8.3 7.1 7.8 24 5.7 3.1 3.0 2 1 1 3 3 3 0 Kisspeptin DUF1977 PF09320.6 KKK20664.1 - 7.3e-29 100.1 0.0 1.2e-28 99.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) DnaJ PF00226.26 KKK20664.1 - 1.3e-23 82.4 0.1 2.6e-23 81.5 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain Meth_synt_2 PF01717.13 KKK20665.1 - 4.2e-144 479.4 0.0 5.2e-140 466.0 0.0 2.5 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 KKK20665.1 - 2.9e-123 411.1 0.0 1.5e-109 366.0 0.0 3.1 3 0 0 3 3 3 3 Cobalamin-independent synthase, N-terminal domain SHOCT PF09851.4 KKK20665.1 - 0.18 11.3 1.2 0.34 10.4 0.1 2.1 2 0 0 2 2 2 0 Short C-terminal domain Steroid_dh PF02544.11 KKK20666.1 - 3.6e-15 56.0 0.2 8.9e-05 22.3 0.0 4.0 4 1 0 4 4 4 3 3-oxo-5-alpha-steroid 4-dehydrogenase SR-25 PF10500.4 KKK20666.1 - 0.013 14.9 15.5 0.018 14.4 10.7 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF1295 PF06966.7 KKK20666.1 - 0.016 14.5 0.0 0.045 13.0 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1295) Shisa PF13908.1 KKK20666.1 - 0.037 14.2 0.0 0.069 13.3 0.0 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF755 PF05501.6 KKK20666.1 - 3.4 7.7 15.3 6.6 6.8 10.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF755) DUF2416 PF10315.4 KKK20667.1 - 2.8e-06 27.5 0.1 3.9e-06 27.0 0.1 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF2416) Ank PF00023.25 KKK20668.1 - 5.2e-22 76.5 0.0 6e-07 28.9 0.0 3.9 4 0 0 4 4 4 3 Ankyrin repeat Ank_2 PF12796.2 KKK20668.1 - 6.8e-21 74.4 0.0 2.5e-20 72.5 0.0 2.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 KKK20668.1 - 9.1e-15 53.3 0.0 0.00024 21.0 0.0 4.6 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.1 KKK20668.1 - 1.7e-13 50.3 0.0 3.6e-05 23.8 0.0 4.1 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 KKK20668.1 - 1.5e-12 47.6 0.1 4.4e-06 27.0 0.0 2.8 1 1 2 3 3 3 3 Ankyrin repeats (many copies) AAA_22 PF13401.1 KKK20668.1 - 2.6e-05 24.3 0.0 0.0023 18.0 0.0 2.7 1 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KKK20668.1 - 4.6e-05 23.4 0.8 0.00045 20.2 0.0 2.9 3 1 0 3 3 3 1 AAA ATPase domain NACHT PF05729.7 KKK20668.1 - 0.0021 17.7 0.0 0.0049 16.5 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_10 PF12846.2 KKK20668.1 - 0.0045 16.4 0.0 0.023 14.1 0.0 2.1 2 1 0 2 2 2 1 AAA-like domain HSA PF07529.8 KKK20669.1 - 3.3e-22 78.0 2.5 3.3e-22 78.0 1.7 3.6 3 0 0 3 3 3 1 HSA Myb_DNA-bind_6 PF13921.1 KKK20669.1 - 3e-16 59.2 2.0 3.4e-16 59.1 0.2 2.2 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 KKK20669.1 - 0.0058 16.6 0.7 0.018 15.1 0.1 2.2 2 0 0 2 2 2 1 Myb-like DNA-binding domain G-patch_2 PF12656.2 KKK20670.1 - 6.5e-29 99.6 0.0 4.1e-28 97.0 0.0 2.4 1 0 0 1 1 1 1 DExH-box splicing factor binding site G-patch PF01585.18 KKK20670.1 - 4e-05 23.3 0.2 9.8e-05 22.0 0.1 1.8 1 0 0 1 1 1 1 G-patch domain Med13_C PF06333.7 KKK20670.1 - 1.8 7.0 3.8 4.4 5.7 2.7 1.6 1 1 0 1 1 1 0 Mediator complex subunit 13 C-terminal WD40 PF00400.27 KKK20671.1 - 7.2e-71 231.7 38.3 1.2e-08 34.5 0.1 12.4 11 2 0 11 11 11 11 WD domain, G-beta repeat Utp13 PF08625.6 KKK20671.1 - 2.1e-44 150.5 0.0 3.5e-44 149.8 0.0 1.4 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain Nup160 PF11715.3 KKK20671.1 - 5.7e-10 37.9 9.5 0.011 13.9 0.8 5.8 2 2 2 5 5 5 5 Nucleoporin Nup120/160 Ribosomal_L34 PF00468.12 KKK20673.1 - 1.1e-16 60.1 11.9 1.7e-16 59.6 8.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L34 RNA_polI_A14 PF08203.6 KKK20674.1 - 0.028 14.6 0.0 0.094 12.9 0.0 1.9 2 0 0 2 2 2 0 Yeast RNA polymerase I subunit RPA14 Peptidase_M48 PF01435.13 KKK20675.1 - 9.2e-51 172.5 0.1 1.4e-50 171.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M48 DUF4538 PF15061.1 KKK20675.1 - 0.0092 15.2 1.2 0.024 13.9 0.8 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4538) Peptidase_M56 PF05569.6 KKK20675.1 - 0.063 12.2 1.7 0.11 11.5 0.5 1.8 2 1 0 2 2 2 0 BlaR1 peptidase M56 DUF2201_N PF13203.1 KKK20675.1 - 0.19 10.8 0.1 0.35 10.0 0.1 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain GTP_EFTU PF00009.22 KKK20676.1 - 2.6e-37 128.0 0.0 4.5e-37 127.3 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain eIF2_C PF09173.6 KKK20676.1 - 5.3e-36 122.5 0.4 1.2e-35 121.3 0.2 1.7 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU_D2 PF03144.20 KKK20676.1 - 1e-11 44.7 0.1 2.7e-11 43.4 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 WD40 PF00400.27 KKK20676.1 - 1.7e-07 30.8 0.0 0.14 12.0 0.0 4.4 4 0 0 4 4 4 3 WD domain, G-beta repeat MMR_HSR1 PF01926.18 KKK20676.1 - 0.049 13.5 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase UCH PF00443.24 KKK20677.1 - 6.5e-23 81.2 0.0 2.1e-21 76.2 0.0 2.1 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 KKK20677.1 - 1.1e-11 44.7 0.1 2.4e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.1 KKK20677.1 - 0.00015 21.2 0.0 0.00021 20.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Proteasome PF00227.21 KKK20678.1 - 1.5e-38 132.0 0.0 1.8e-38 131.7 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Pro_isomerase PF00160.16 KKK20679.1 - 1.5e-45 155.2 0.3 2e-45 154.7 0.2 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Glyco_hydro_71 PF03659.9 KKK20680.1 - 7.1e-135 449.3 8.3 8.3e-135 449.1 5.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 Glyco_hydro_71 PF03659.9 KKK20681.1 - 4.3e-143 476.4 9.6 5e-143 476.2 6.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 DUF4434 PF14488.1 KKK20681.1 - 0.032 13.9 0.4 0.087 12.5 0.2 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4434) TUG-UBL1 PF11470.3 KKK20682.1 - 4.6e-25 87.3 0.1 1.3e-24 85.8 0.0 1.9 2 0 0 2 2 2 1 GLUT4 regulating protein TUG UBX PF00789.15 KKK20682.1 - 0.00036 20.5 0.3 0.0024 17.9 0.0 2.3 2 0 0 2 2 2 1 UBX domain RBD PF02196.10 KKK20682.1 - 0.06 13.1 0.1 0.4 10.4 0.0 2.3 2 0 0 2 2 2 0 Raf-like Ras-binding domain DUF605 PF04652.11 KKK20682.1 - 9.7 5.4 21.7 0.87 8.9 11.0 1.8 2 0 0 2 2 2 0 Vta1 like Ribosomal_L36e PF01158.13 KKK20683.1 - 1.3e-23 82.7 0.3 2.1e-23 82.1 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L36e PT PF04886.7 KKK20683.1 - 0.35 10.2 16.4 0.17 11.2 9.3 2.0 2 0 0 2 2 2 0 PT repeat NatB_MDM20 PF09797.4 KKK20685.1 - 1.5e-104 349.5 0.0 2.4e-104 348.9 0.0 1.3 1 0 0 1 1 1 1 N-acetyltransferase B complex (NatB) non catalytic subunit TPR_19 PF14559.1 KKK20685.1 - 0.00012 22.3 4.6 0.0048 17.2 0.4 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 KKK20685.1 - 0.0011 19.6 2.9 0.01 16.4 0.4 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 KKK20685.1 - 0.0091 16.5 2.7 13 6.7 0.5 4.5 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF4363 PF14276.1 KKK20685.1 - 0.14 11.8 1.1 9.9 5.8 0.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4363) DUF1903 PF08991.5 KKK20686.1 - 0.0017 18.5 0.3 0.0032 17.6 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1903) CHCH PF06747.8 KKK20686.1 - 0.21 11.5 4.5 0.32 10.9 0.9 2.5 2 1 0 2 2 2 0 CHCH domain 2OG-FeII_Oxy_3 PF13640.1 KKK20687.1 - 0.0028 18.1 0.0 0.0058 17.1 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily BAR_2 PF10455.4 KKK20687.1 - 0.18 10.7 1.5 0.3 9.9 1.0 1.3 1 0 0 1 1 1 0 Bin/amphiphysin/Rvs domain for vesicular trafficking zf-RING_2 PF13639.1 KKK20688.1 - 6.3e-09 35.5 6.7 6.3e-09 35.5 4.7 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 KKK20688.1 - 1.5e-08 34.1 4.6 1.5e-08 34.1 3.2 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KKK20688.1 - 1.7e-07 31.1 7.0 1.7e-07 31.1 4.8 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KKK20688.1 - 2.8e-07 30.1 2.8 2.8e-07 30.1 2.0 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KKK20688.1 - 5.3e-07 29.4 7.7 5.3e-07 29.4 5.3 2.2 2 1 1 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 KKK20688.1 - 9.5e-07 28.4 5.4 9.5e-07 28.4 3.7 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 KKK20688.1 - 0.00096 18.8 2.7 0.0021 17.7 1.9 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_6 PF14835.1 KKK20688.1 - 0.0047 16.6 2.7 0.0047 16.6 1.9 2.1 2 0 0 2 2 2 1 zf-RING of BARD1-type protein DZR PF12773.2 KKK20688.1 - 0.0082 15.9 9.9 0.73 9.7 0.1 2.5 2 0 0 2 2 2 2 Double zinc ribbon zf-rbx1 PF12678.2 KKK20688.1 - 0.074 13.1 8.4 0.036 14.1 2.3 2.6 2 1 0 2 2 2 0 RING-H2 zinc finger zf-RING_4 PF14570.1 KKK20688.1 - 0.28 10.8 9.4 0.047 13.2 1.9 2.6 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-Apc11 PF12861.2 KKK20688.1 - 0.52 10.1 5.9 0.077 12.8 0.7 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger IBR PF01485.16 KKK20688.1 - 8.5 6.3 12.6 11 6.0 3.5 2.9 1 1 1 2 2 2 0 IBR domain WD40 PF00400.27 KKK20689.1 - 7e-32 108.1 11.5 1.7e-08 34.0 0.0 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 KKK20689.1 - 0.00068 17.8 0.6 3.3 5.7 0.0 4.2 3 1 1 5 5 5 4 Nucleoporin Nup120/160 EHN PF06441.7 KKK20690.1 - 9.4e-35 118.9 4.1 1.8e-34 118.0 0.1 2.5 3 0 0 3 3 3 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 KKK20690.1 - 6.1e-17 62.2 1.3 9.8e-17 61.5 0.1 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KKK20690.1 - 1e-12 48.1 0.0 2.8e-12 46.7 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Proteasome PF00227.21 KKK20691.1 - 4.8e-38 130.3 0.0 5.3e-38 130.2 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Peptidase_M16_C PF05193.16 KKK20693.1 - 2.6e-18 66.3 0.0 1.6e-13 50.7 0.0 3.0 2 1 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 KKK20693.1 - 2e-05 24.3 0.0 8.3e-05 22.3 0.0 2.1 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Astro_capsid PF03115.9 KKK20693.1 - 0.29 9.3 1.4 0.4 8.8 1.0 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor Cwf_Cwc_15 PF04889.7 KKK20693.1 - 1.5 8.4 14.9 0.072 12.7 5.6 2.0 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Sporozoite_P67 PF05642.6 KKK20693.1 - 1.7 6.3 5.7 2.4 5.8 4.0 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen WD40 PF00400.27 KKK20694.1 - 2.4e-28 96.9 23.8 3.4e-07 29.8 0.1 7.1 7 0 0 7 7 7 5 WD domain, G-beta repeat NLE PF08154.7 KKK20694.1 - 7.6e-21 73.9 0.2 2.5e-20 72.2 0.1 2.1 2 0 0 2 2 2 1 NLE (NUC135) domain Zw10 PF06248.8 KKK20694.1 - 9.3e-17 60.3 1.4 1.2e-14 53.3 0.2 2.2 2 0 0 2 2 2 2 Centromere/kinetochore Zw10 Dsl1_C PF11989.3 KKK20694.1 - 1e-07 31.4 0.1 2.4e-07 30.1 0.1 1.6 1 0 0 1 1 1 1 Retrograde transport protein Dsl1 C terminal GTP_EFTU PF00009.22 KKK20698.1 - 9.1e-15 54.5 0.0 9.1e-15 54.5 0.0 1.0 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain DUF3558 PF12079.3 KKK20698.1 - 0.035 13.7 0.0 0.036 13.7 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3558) Fibrinogen_aC PF12160.3 KKK20698.1 - 0.054 12.9 0.0 0.062 12.7 0.0 1.2 1 0 0 1 1 1 0 Fibrinogen alpha C domain SRPRB PF09439.5 KKK20698.1 - 0.11 11.7 0.0 0.12 11.5 0.0 1.1 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Pkinase PF00069.20 KKK20699.1 - 8.6e-62 208.6 0.0 1.1e-61 208.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK20699.1 - 1.4e-36 125.9 0.0 1.9e-36 125.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KKK20699.1 - 2e-09 36.8 0.0 2.9e-09 36.2 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 KKK20699.1 - 0.14 10.9 0.0 0.2 10.4 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.9 KKK20699.1 - 0.22 10.5 0.0 0.37 9.8 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PLRV_ORF5 PF01690.12 KKK20699.1 - 6.6 5.7 12.9 11 5.0 9.0 1.2 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Prp18 PF02840.10 KKK20722.1 - 3e-55 186.0 0.2 3e-55 186.0 0.1 1.9 2 0 0 2 2 2 1 Prp18 domain PRP4 PF08799.6 KKK20722.1 - 4.2e-09 35.4 6.3 4.2e-09 35.4 4.3 3.2 3 0 0 3 3 3 1 pre-mRNA processing factor 4 (PRP4) like MIP-T3 PF10243.4 KKK20722.1 - 0.037 12.5 26.0 0.044 12.2 18.0 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 CAF-1_p150 PF11600.3 KKK20722.1 - 1.6 8.0 37.0 2.6 7.3 25.7 1.4 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Ycf1 PF05758.7 KKK20722.1 - 1.7 6.2 7.0 1.7 6.2 4.9 1.1 1 0 0 1 1 1 0 Ycf1 Pyr_redox_3 PF13738.1 KKK20723.1 - 5.9e-05 23.2 0.0 0.00033 20.7 0.0 2.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KKK20723.1 - 0.011 15.4 0.0 0.083 12.6 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding 2-Hacid_dh_C PF02826.14 KKK20724.1 - 8.8e-49 165.0 0.0 1.2e-48 164.5 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KKK20724.1 - 3e-29 101.1 0.0 3.6e-29 100.9 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AdoHcyase_NAD PF00670.16 KKK20724.1 - 0.052 13.3 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain AlaDh_PNT_C PF01262.16 KKK20724.1 - 0.087 12.3 0.1 15 5.1 0.1 2.2 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain GST_N PF02798.15 KKK20725.1 - 8.6e-11 41.8 0.0 2.6e-10 40.3 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 KKK20725.1 - 9.4e-11 41.7 0.0 1.6e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KKK20725.1 - 1.7e-09 37.5 0.0 3e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KKK20725.1 - 2.8e-06 27.1 0.0 4.7e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KKK20725.1 - 1.2e-05 25.1 0.0 2.6e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KKK20725.1 - 2.8e-05 24.5 0.0 4.4e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain NDUF_B4 PF07225.7 KKK20726.1 - 1.7e-05 24.6 0.0 1.9e-05 24.4 0.0 1.0 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) MitoNEET_N PF10660.4 KKK20726.1 - 0.028 14.2 0.3 0.039 13.8 0.2 1.2 1 0 0 1 1 1 0 Iron-containing outer mitochondrial membrane protein N-terminus BCCT PF02028.12 KKK20726.1 - 0.1 10.8 0.1 0.11 10.7 0.0 1.0 1 0 0 1 1 1 0 BCCT family transporter SAP18 PF06487.7 KKK20727.1 - 8.8e-49 164.3 0.0 1e-48 164.0 0.0 1.0 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) Use1 PF09753.4 KKK20728.1 - 1e-11 44.7 0.6 1.7e-11 44.0 0.4 1.5 1 1 0 1 1 1 1 Membrane fusion protein Use1 GldM_N PF12081.3 KKK20728.1 - 0.0058 16.1 0.3 0.0058 16.1 0.2 1.6 2 0 0 2 2 2 1 GldM N-terminal domain DUF3596 PF12167.3 KKK20728.1 - 0.077 12.5 1.0 0.59 9.6 0.1 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF3596) Hid1 PF12722.2 KKK20728.1 - 0.45 8.1 6.1 0.62 7.6 4.3 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF605 PF04652.11 KKK20728.1 - 1.3 8.2 13.4 1.7 7.9 9.3 1.1 1 0 0 1 1 1 0 Vta1 like Tmemb_cc2 PF10267.4 KKK20728.1 - 5.1 5.5 11.1 3.8e+02 -0.6 7.7 2.2 1 1 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Pneumo_att_G PF05539.6 KKK20728.1 - 6.2 6.0 20.6 9.4 5.4 14.3 1.3 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G Synaptobrevin PF00957.16 KKK20728.1 - 7.8 6.1 6.6 1.2 8.7 0.2 2.6 2 1 1 3 3 3 0 Synaptobrevin DUF572 PF04502.8 KKK20728.1 - 8.9 5.4 11.8 15 4.6 8.0 1.5 1 1 0 1 1 1 0 Family of unknown function (DUF572) AMP-binding PF00501.23 KKK20729.1 - 1.6e-72 244.2 0.0 4.2e-72 242.8 0.0 1.6 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KKK20729.1 - 1.4e-13 51.5 0.2 4.8e-13 49.8 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain DUF1180 PF06679.7 KKK20730.1 - 9.7 6.0 6.0 7.7 6.3 0.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1180) IGPS PF00218.16 KKK20731.1 - 2.2e-98 328.3 0.0 7.5e-98 326.6 0.0 1.8 2 0 0 2 2 2 1 Indole-3-glycerol phosphate synthase PRAI PF00697.17 KKK20731.1 - 2.8e-57 193.4 0.1 5.3e-56 189.2 0.0 2.6 2 1 1 3 3 3 1 N-(5'phosphoribosyl)anthranilate (PRA) isomerase GATase PF00117.23 KKK20731.1 - 2.6e-52 177.0 0.0 4.2e-52 176.4 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 KKK20731.1 - 0.00026 20.4 0.3 0.0011 18.4 0.2 1.9 1 1 0 1 1 1 1 Peptidase C26 QRPTase_C PF01729.14 KKK20731.1 - 0.00058 19.4 0.2 0.0055 16.2 0.0 2.6 3 0 0 3 3 3 1 Quinolinate phosphoribosyl transferase, C-terminal domain His_biosynth PF00977.16 KKK20731.1 - 0.0049 16.1 0.1 0.018 14.3 0.0 1.9 2 0 0 2 2 2 1 Histidine biosynthesis protein NanE PF04131.9 KKK20731.1 - 0.017 14.0 0.4 0.071 12.0 0.0 2.2 3 0 0 3 3 3 0 Putative N-acetylmannosamine-6-phosphate epimerase Nup188 PF10487.4 KKK20732.1 - 1.5e-48 165.4 0.0 2.8e-48 164.5 0.0 1.4 1 0 0 1 1 1 1 Nucleoporin subcomplex protein binding to Pom34 Brix PF04427.13 KKK20733.1 - 2.6e-45 154.4 0.0 3.3e-45 154.0 0.0 1.1 1 0 0 1 1 1 1 Brix domain PTCB-BRCT PF12738.2 KKK20734.1 - 6.5e-12 45.1 0.2 1e-11 44.5 0.2 1.3 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 KKK20734.1 - 1.1e-08 35.0 0.1 1.8e-08 34.3 0.1 1.4 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain UPF1_Zn_bind PF09416.5 KKK20735.1 - 1.8e-73 245.1 3.1 2e-73 245.0 1.2 1.8 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.1 KKK20735.1 - 4.4e-60 202.5 0.0 6.8e-60 201.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KKK20735.1 - 2.3e-57 194.3 0.8 3.6e-57 193.6 0.6 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KKK20735.1 - 1.2e-14 53.7 0.2 3.4e-14 52.3 0.2 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 KKK20735.1 - 6.3e-12 45.4 0.1 1.3e-10 41.1 0.1 2.4 1 1 0 1 1 1 1 AAA domain ResIII PF04851.10 KKK20735.1 - 9e-08 32.1 0.0 1.8e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.13 KKK20735.1 - 7.2e-05 22.4 0.2 0.61 9.5 0.0 2.9 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.9 KKK20735.1 - 0.00059 19.5 0.0 0.0013 18.4 0.0 1.6 1 0 0 1 1 1 1 Helicase PIF1 PF05970.9 KKK20735.1 - 0.0022 17.0 0.1 0.37 9.7 0.0 2.2 2 0 0 2 2 2 1 PIF1-like helicase DUF2075 PF09848.4 KKK20735.1 - 0.0036 16.3 0.9 0.0097 14.9 0.0 2.2 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) UvrD-helicase PF00580.16 KKK20735.1 - 0.007 15.7 0.1 0.049 12.9 0.0 2.2 2 1 0 3 3 3 1 UvrD/REP helicase N-terminal domain DEAD PF00270.24 KKK20735.1 - 0.01 15.3 0.0 0.028 13.9 0.0 1.7 2 0 0 2 2 2 0 DEAD/DEAH box helicase AAA_16 PF13191.1 KKK20735.1 - 0.016 15.1 0.1 0.035 14.0 0.1 1.5 1 0 0 1 1 1 0 AAA ATPase domain KaiC PF06745.8 KKK20735.1 - 0.03 13.4 0.0 0.071 12.2 0.0 1.5 1 0 0 1 1 1 0 KaiC AAA_25 PF13481.1 KKK20735.1 - 0.061 12.7 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 KKK20735.1 - 0.099 12.7 0.1 0.35 11.0 0.1 2.0 1 1 0 1 1 1 0 AAA domain zf-RanBP PF00641.13 KKK20735.1 - 3.4 6.8 7.4 0.37 9.9 1.6 2.0 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others zf-C2H2_4 PF13894.1 KKK20736.1 - 5.1e-08 32.7 9.6 0.056 13.7 0.2 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.21 KKK20736.1 - 3.5e-05 23.8 15.2 0.36 11.2 0.1 3.9 3 1 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KKK20736.1 - 0.013 15.8 13.8 0.027 14.7 0.1 3.5 3 0 0 3 3 3 0 Zinc-finger double domain Microtub_assoc PF07989.6 KKK20736.1 - 0.065 13.0 1.3 0.16 11.8 0.1 2.0 2 0 0 2 2 2 0 Microtubule associated zf-H2C2_5 PF13909.1 KKK20736.1 - 0.21 11.8 3.7 2.5 8.4 0.2 2.9 2 1 0 2 2 2 0 C2H2-type zinc-finger domain SRP19 PF01922.12 KKK20737.1 - 3e-31 107.8 0.0 4.4e-31 107.3 0.0 1.3 1 0 0 1 1 1 1 SRP19 protein Fungal_trans PF04082.13 KKK20738.1 - 1.1e-16 60.5 0.1 2e-16 59.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK20738.1 - 4.3e-10 39.3 10.5 8e-10 38.4 7.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AAA_7 PF12775.2 KKK20738.1 - 0.025 13.6 0.0 0.041 12.9 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region D3 MIP-T3 PF10243.4 KKK20738.1 - 0.19 10.1 0.1 0.32 9.4 0.1 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 IncA PF04156.9 KKK20738.1 - 0.36 10.4 0.2 0.76 9.3 0.1 1.4 1 0 0 1 1 1 0 IncA protein YvrJ PF12841.2 KKK20738.1 - 1.2 8.4 3.3 0.6 9.4 0.3 2.0 2 0 0 2 2 2 0 YvrJ protein family TCTP PF00838.12 KKK20739.1 - 4.8e-44 150.2 0.7 5.8e-44 149.9 0.5 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein FA_hydroxylase PF04116.8 KKK20740.1 - 5.9e-19 68.5 11.3 5.9e-19 68.5 7.8 2.0 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily DUF3089 PF11288.3 KKK20741.1 - 0.037 13.1 0.0 0.06 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) DEAD PF00270.24 KKK20742.1 - 9.3e-34 116.3 0.0 2.1e-16 59.8 0.0 2.5 1 1 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 KKK20742.1 - 3.6e-17 62.0 0.2 8.5e-17 60.7 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KKK20742.1 - 3.4e-06 27.0 0.0 3.4e-06 27.0 0.0 3.1 3 2 0 3 3 3 1 Type III restriction enzyme, res subunit Nop14 PF04147.7 KKK20742.1 - 2.8e-05 22.2 13.8 2.8e-05 22.2 9.5 2.1 2 0 0 2 2 2 1 Nop14-like family MIP-T3 PF10243.4 KKK20742.1 - 0.098 11.1 53.5 0.071 11.5 5.2 2.1 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 PIGA PF08288.7 KKK20743.1 - 3.9e-47 158.5 4.5 4.1e-47 158.4 1.1 2.2 2 0 0 2 2 2 1 PIGA (GPI anchor biosynthesis) Glycos_transf_1 PF00534.15 KKK20743.1 - 4.5e-29 101.0 0.0 7.2e-29 100.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 KKK20743.1 - 7.7e-17 61.7 0.0 1.3e-16 60.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 KKK20743.1 - 2.1e-16 60.1 0.7 4e-16 59.2 0.5 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.1 KKK20743.1 - 1.5e-14 54.4 0.0 2.4e-14 53.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.1 KKK20743.1 - 0.00013 21.8 0.3 0.00027 20.7 0.2 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.1 KKK20743.1 - 0.0059 16.8 0.0 0.016 15.4 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 Arf PF00025.16 KKK20744.1 - 1.9e-40 137.9 0.0 2e-26 92.3 0.0 2.3 2 1 0 2 2 2 2 ADP-ribosylation factor family G-alpha PF00503.15 KKK20744.1 - 4.8e-14 51.8 0.0 3.9e-07 29.1 0.0 2.3 2 1 0 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 KKK20744.1 - 2.6e-07 30.0 0.0 4e-07 29.4 0.0 1.5 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 KKK20744.1 - 6.4e-07 29.8 0.0 3.5e-06 27.5 0.0 2.0 2 0 0 2 2 2 1 Miro-like protein Ras PF00071.17 KKK20744.1 - 1.4e-06 27.7 0.0 0.0047 16.3 0.0 2.8 2 1 0 2 2 2 2 Ras family SRPRB PF09439.5 KKK20744.1 - 5.1e-06 25.8 0.0 8.2e-05 21.9 0.0 2.1 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 KKK20744.1 - 1.5e-05 24.9 0.0 7.2e-05 22.7 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KKK20744.1 - 2.7e-05 23.6 0.0 0.00083 18.8 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain LSM PF01423.17 KKK20780.1 - 5.9e-06 25.7 0.0 7.3e-06 25.4 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 KKK20780.1 - 0.0083 16.0 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain Metallophos PF00149.23 KKK20781.1 - 4.3e-41 140.5 0.2 5.7e-41 140.1 0.2 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase WD40 PF00400.27 KKK20782.1 - 2.9e-13 49.1 12.4 0.27 11.1 0.0 8.6 9 0 0 9 9 9 5 WD domain, G-beta repeat Lactonase PF10282.4 KKK20782.1 - 0.0021 17.2 0.0 0.31 10.0 0.0 2.4 2 0 0 2 2 2 2 Lactonase, 7-bladed beta-propeller Cyclin_N PF00134.18 KKK20783.1 - 1.1e-34 118.7 0.1 1.1e-34 118.7 0.1 1.7 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 KKK20783.1 - 5.4e-14 52.1 0.1 1.1e-13 51.1 0.1 1.5 1 0 0 1 1 1 1 Cyclin, C-terminal domain Memo PF01875.12 KKK20784.1 - 1.9e-64 217.1 0.0 2.3e-64 216.9 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein DUF1469 PF07332.6 KKK20786.1 - 0.036 13.7 0.2 0.036 13.7 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1469) NPCC PF08058.6 KKK20786.1 - 0.42 10.4 2.8 0.53 10.1 0.1 2.4 3 0 0 3 3 3 0 Nuclear pore complex component DHHA2 PF02833.9 KKK20787.1 - 1.1e-19 70.9 0.0 1.5e-19 70.4 0.0 1.2 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.15 KKK20787.1 - 1.5e-07 31.1 0.1 2.9e-06 26.9 0.0 2.3 1 1 0 1 1 1 1 DHH family adh_short PF00106.20 KKK20788.1 - 4.1e-15 56.0 0.2 7e-14 52.0 0.0 2.3 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KKK20788.1 - 1.5e-08 34.5 0.0 4.6e-08 32.9 0.0 1.7 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.10 KKK20788.1 - 0.0022 16.9 0.0 0.0045 15.9 0.0 1.5 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 KKK20788.1 - 0.0029 17.0 0.0 0.011 15.1 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Glyco_tran_WecB PF03808.8 KKK20788.1 - 0.014 14.7 0.1 2.6 7.3 0.0 2.6 2 1 1 3 3 3 0 Glycosyl transferase WecB/TagA/CpsF family Shikimate_DH PF01488.15 KKK20788.1 - 0.039 14.0 0.0 0.072 13.1 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF3940 PF13076.1 KKK20788.1 - 0.056 13.0 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3940) YrhK PF14145.1 KKK20789.1 - 0.00039 20.0 18.5 0.18 11.5 0.4 5.0 3 2 2 5 5 5 4 YrhK-like protein WD40 PF00400.27 KKK20790.1 - 2.8e-31 106.2 6.8 2.1e-07 30.5 0.0 7.0 7 1 0 7 7 7 5 WD domain, G-beta repeat HIRA_B PF09453.5 KKK20790.1 - 2.7e-05 23.5 0.1 2.7e-05 23.5 0.1 2.2 2 0 0 2 2 2 1 HIRA B motif eIF2A PF08662.6 KKK20790.1 - 3.6e-05 23.5 0.4 0.037 13.7 0.0 2.8 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 KKK20790.1 - 0.085 12.5 2.6 14 5.4 0.0 3.6 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Rad4 PF03835.10 KKK20792.1 - 2.6e-14 52.8 4.6 5.8e-14 51.7 3.2 1.6 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain Transglut_core PF01841.14 KKK20792.1 - 7.5e-13 48.6 2.0 1.8e-12 47.4 1.4 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily DUF2235 PF09994.4 KKK20793.1 - 5.3e-84 281.8 0.0 6.8e-84 281.5 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) MoCF_biosynth PF00994.19 KKK20794.1 - 2.6e-46 156.6 0.0 1.6e-24 85.9 0.0 2.3 2 0 0 2 2 2 2 Probable molybdopterin binding domain MoeA_N PF03453.12 KKK20794.1 - 1.5e-33 115.4 1.4 2.2e-33 114.9 1.0 1.3 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.10 KKK20794.1 - 1.6e-16 60.0 0.1 4e-16 58.7 0.1 1.8 1 0 0 1 1 1 1 MoeA C-terminal region (domain IV) FSH1 PF03959.8 KKK20795.1 - 4.8e-25 88.2 0.0 5.7e-25 88.0 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.2 KKK20795.1 - 3.4e-05 23.6 0.1 5e-05 23.0 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KKK20795.1 - 0.084 12.4 0.1 3.8 6.9 0.0 2.1 1 1 1 2 2 2 0 alpha/beta hydrolase fold XPA_C PF05181.7 KKK20796.1 - 3.6e-29 100.1 3.6 3.6e-29 100.1 2.5 1.9 2 0 0 2 2 2 1 XPA protein C-terminus XPA_N PF01286.13 KKK20796.1 - 0.00042 19.9 3.9 0.00042 19.9 2.7 2.1 2 0 0 2 2 2 1 XPA protein N-terminal YhfH PF14149.1 KKK20796.1 - 0.41 10.4 11.6 0.28 10.9 0.7 2.6 2 0 0 2 2 2 0 YhfH-like protein zf-DHHC PF01529.15 KKK20796.1 - 2.2 7.6 4.5 4.1 6.7 3.1 1.6 1 1 0 1 1 1 0 DHHC palmitoyltransferase ArfGap PF01412.13 KKK20796.1 - 4.4 7.1 8.4 1.1 9.0 0.9 2.8 3 0 0 3 3 3 0 Putative GTPase activating protein for Arf YrhK PF14145.1 KKK20835.1 - 2.2 8.0 6.0 4.5 6.9 0.1 3.2 3 0 0 3 3 3 0 YrhK-like protein Stb3 PF10330.4 KKK20836.1 - 1e-37 127.6 0.0 1.6e-37 127.0 0.0 1.3 1 0 0 1 1 1 1 Putative Sin3 binding protein HNH_2 PF13391.1 KKK20837.1 - 9.5e-15 54.1 0.1 4.9e-14 51.8 0.0 2.2 2 0 0 2 2 2 1 HNH endonuclease Ifi-6-16 PF06140.8 KKK20843.1 - 0.00049 19.8 25.8 0.00049 19.8 17.9 1.9 2 0 0 2 2 2 1 Interferon-induced 6-16 family NMO PF03060.10 KKK20844.1 - 4.5e-33 114.8 2.7 1.7e-25 89.8 0.5 2.1 2 0 0 2 2 2 2 Nitronate monooxygenase IMPDH PF00478.20 KKK20844.1 - 5.2e-09 35.4 0.1 5.8e-05 22.1 1.3 2.1 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 KKK20844.1 - 1.8e-06 27.0 1.2 2.8e-06 26.4 0.9 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.12 KKK20844.1 - 0.0043 16.0 0.5 0.0067 15.3 0.3 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase DHO_dh PF01180.16 KKK20844.1 - 0.011 14.6 0.1 0.017 14.0 0.1 1.2 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase ThiG PF05690.9 KKK20844.1 - 0.098 11.7 0.1 0.23 10.4 0.1 1.5 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG His_biosynth PF00977.16 KKK20844.1 - 0.11 11.7 0.0 0.38 9.9 0.0 1.8 2 0 0 2 2 2 0 Histidine biosynthesis protein Stk19 PF10494.4 KKK20845.1 - 2e-79 266.5 0.0 2.4e-79 266.2 0.0 1.1 1 0 0 1 1 1 1 Serine-threonine protein kinase 19 NmrA PF05368.8 KKK20847.1 - 2.4e-38 131.6 0.0 2.5e-38 131.6 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KKK20847.1 - 6.9e-09 35.9 0.0 1.5e-08 34.8 0.0 1.6 2 0 0 2 2 2 1 NADH(P)-binding TrkA_N PF02254.13 KKK20847.1 - 0.00015 21.7 0.1 0.0032 17.4 0.1 2.2 2 0 0 2 2 2 1 TrkA-N domain 3Beta_HSD PF01073.14 KKK20847.1 - 0.00029 19.6 0.0 0.00038 19.2 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 KKK20847.1 - 0.00056 19.4 0.0 0.00076 18.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DapB_N PF01113.15 KKK20847.1 - 0.018 14.9 0.1 0.033 14.1 0.1 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus adh_short PF00106.20 KKK20847.1 - 0.019 14.9 0.3 0.032 14.1 0.2 1.4 1 0 0 1 1 1 0 short chain dehydrogenase zf-C3HC4_2 PF13923.1 KKK20849.1 - 0.035 14.1 1.3 0.035 14.1 0.9 3.0 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-CHY PF05495.7 KKK20849.1 - 3.9 7.7 7.0 4.7 7.4 0.8 2.8 2 1 0 2 2 2 0 CHY zinc finger Atg14 PF10186.4 KKK20849.1 - 4 6.3 14.9 9.2 5.1 10.3 1.6 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 SnoaL PF07366.7 KKK20850.1 - 0.00017 21.1 0.0 0.00032 20.2 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.2 KKK20850.1 - 0.0027 18.0 0.0 0.0051 17.2 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like domain Pyr_redox_3 PF13738.1 KKK20851.1 - 1.2e-23 84.2 0.0 2.1e-23 83.4 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KKK20851.1 - 5.9e-13 47.8 0.0 1.9e-11 42.9 0.0 2.1 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 KKK20851.1 - 1.1e-07 32.0 0.0 4.2e-07 30.0 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KKK20851.1 - 1.1e-05 25.2 0.3 8.5e-05 22.3 0.0 2.6 3 1 0 3 3 3 1 FAD-NAD(P)-binding K_oxygenase PF13434.1 KKK20851.1 - 1.2e-05 24.4 0.0 7.5e-05 21.8 0.0 2.0 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 KKK20851.1 - 2e-05 24.4 0.9 0.00014 21.8 0.0 2.7 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KKK20851.1 - 0.00051 19.1 0.8 0.38 9.8 0.0 2.2 2 0 0 2 2 2 2 Thi4 family FAD_oxidored PF12831.2 KKK20851.1 - 0.046 12.8 0.0 0.11 11.4 0.0 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox PF00070.22 KKK20851.1 - 0.06 13.7 0.5 7.3 7.0 0.1 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KKK20851.1 - 0.084 11.6 0.0 0.13 11.0 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.9 KKK20851.1 - 0.19 10.1 0.0 2.1 6.7 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein Fungal_trans PF04082.13 KKK20852.1 - 8.6e-28 96.9 4.2 1.5e-27 96.1 2.9 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2_4 PF13894.1 KKK20852.1 - 5e-07 29.6 14.7 0.0018 18.4 0.5 3.8 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KKK20852.1 - 3.3e-06 27.1 15.0 0.004 17.4 0.2 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 KKK20852.1 - 0.38 10.7 0.1 0.38 10.7 0.0 2.9 3 0 0 3 3 3 0 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KKK20852.1 - 4.9 7.6 12.3 5.4 7.4 0.4 3.4 3 0 0 3 3 3 0 Zinc-finger double domain Methyltransf_12 PF08242.7 KKK20854.1 - 2.5e-13 50.3 0.0 8.3e-13 48.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 KKK20854.1 - 5.4e-13 48.9 0.0 1e-12 48.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KKK20854.1 - 2.1e-12 47.3 0.0 3e-11 43.6 0.0 2.8 3 1 0 3 3 3 1 Methyltransferase domain Methyltransf_25 PF13649.1 KKK20854.1 - 1.4e-11 44.5 0.0 5.9e-11 42.6 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KKK20854.1 - 1e-09 38.9 0.0 3.5e-09 37.2 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KKK20854.1 - 6.6e-09 35.5 0.0 1.1e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KKK20854.1 - 1.5e-07 30.7 0.0 5.9e-07 28.8 0.0 1.8 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 KKK20854.1 - 8.6e-06 25.7 0.0 2.6e-05 24.2 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain DUF3419 PF11899.3 KKK20854.1 - 0.00026 19.8 0.0 0.00054 18.7 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3419) MTS PF05175.9 KKK20854.1 - 0.00087 18.7 0.0 0.0016 17.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_24 PF13578.1 KKK20854.1 - 0.0024 18.6 0.0 0.073 13.9 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_8 PF05148.10 KKK20854.1 - 0.0049 16.5 0.0 0.58 9.7 0.0 2.4 2 1 0 2 2 2 1 Hypothetical methyltransferase NNMT_PNMT_TEMT PF01234.12 KKK20854.1 - 0.008 15.1 0.0 0.2 10.6 0.0 2.4 1 1 1 3 3 3 1 NNMT/PNMT/TEMT family Endonuclease_NS PF01223.18 KKK20855.1 - 2.2e-60 203.8 0.0 3.2e-60 203.3 0.0 1.2 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease DUF2722 PF10846.3 KKK20855.1 - 0.1 11.5 2.6 0.14 11.1 1.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Mpv17_PMP22 PF04117.7 KKK20898.1 - 7.5e-14 51.1 0.8 1.1e-11 44.2 0.4 2.3 2 0 0 2 2 2 2 Mpv17 / PMP22 family Cullin_binding PF03556.10 KKK20899.1 - 4.1e-31 107.5 0.2 5.2e-31 107.1 0.1 1.1 1 0 0 1 1 1 1 Cullin binding Dscam_C PF12355.3 KKK20900.1 - 6.5 7.0 7.0 17 5.6 1.8 2.6 2 0 0 2 2 2 0 Down syndrome cell adhesion molecule C terminal PEX11 PF05648.9 KKK20901.1 - 2.6e-09 36.6 0.2 1.3e-07 31.0 0.1 2.1 1 1 1 2 2 2 2 Peroxisomal biogenesis factor 11 (PEX11) DUF2269 PF10027.4 KKK20901.1 - 0.11 12.2 2.6 0.11 12.2 0.5 1.9 2 0 0 2 2 2 0 Predicted integral membrane protein (DUF2269) AIG2 PF06094.7 KKK20902.1 - 1.2e-08 35.3 0.0 1.6e-08 34.9 0.0 1.2 1 0 0 1 1 1 1 AIG2-like family DUF1039 PF06287.6 KKK20902.1 - 0.049 13.5 0.0 0.09 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1039) AAA PF00004.24 KKK20903.1 - 1.6e-97 322.7 0.0 2.4e-47 160.4 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 KKK20903.1 - 1.4e-18 66.6 0.5 4.8e-18 64.8 0.3 2.0 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_2 PF07724.9 KKK20903.1 - 2.4e-14 53.6 0.0 8.8e-08 32.2 0.0 2.9 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 KKK20903.1 - 1.3e-13 50.5 0.0 7.7e-06 25.1 0.0 2.8 3 0 0 3 3 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 KKK20903.1 - 5.4e-13 49.0 0.0 7.1e-06 25.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 KKK20903.1 - 2.6e-12 46.6 0.5 5.3e-06 26.1 0.1 3.8 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KKK20903.1 - 1e-11 45.0 0.2 0.0018 18.3 0.0 4.2 2 2 0 2 2 2 2 AAA domain AAA_17 PF13207.1 KKK20903.1 - 2.8e-11 44.2 0.0 0.00047 20.9 0.0 3.0 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.1 KKK20903.1 - 8.7e-11 42.1 0.0 0.0022 18.0 0.0 3.7 2 2 1 3 3 3 2 AAA ATPase domain TIP49 PF06068.8 KKK20903.1 - 2.6e-09 36.2 0.1 0.00096 17.9 0.0 2.8 2 0 0 2 2 2 2 TIP49 C-terminus CDC48_2 PF02933.12 KKK20903.1 - 2.9e-08 33.2 0.0 7.4e-08 31.9 0.0 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_14 PF13173.1 KKK20903.1 - 4.8e-08 32.9 0.0 0.0036 17.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 KKK20903.1 - 4.9e-08 32.5 4.5 0.037 13.4 0.0 4.3 2 2 1 4 4 4 2 AAA domain IstB_IS21 PF01695.12 KKK20903.1 - 6e-08 32.3 0.0 0.0053 16.1 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein Zeta_toxin PF06414.7 KKK20903.1 - 1.2e-07 31.0 0.0 0.0074 15.3 0.0 2.7 2 0 0 2 2 2 2 Zeta toxin Mg_chelatase PF01078.16 KKK20903.1 - 1.3e-07 31.0 0.8 0.0084 15.2 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 KKK20903.1 - 1.6e-07 30.9 1.3 0.0083 15.8 0.0 2.9 2 0 0 2 2 2 2 Part of AAA domain RNA_helicase PF00910.17 KKK20903.1 - 5.3e-07 29.7 0.0 0.024 14.7 0.0 2.8 2 0 0 2 2 2 2 RNA helicase ResIII PF04851.10 KKK20903.1 - 2.2e-06 27.6 0.0 0.0035 17.1 0.0 2.5 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit KaiC PF06745.8 KKK20903.1 - 4e-06 26.1 2.9 0.45 9.6 0.0 3.9 3 1 1 4 4 4 2 KaiC AAA_18 PF13238.1 KKK20903.1 - 4.9e-06 26.8 0.0 0.085 13.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.1 KKK20903.1 - 6.2e-06 26.2 0.1 0.09 12.7 0.0 2.7 3 0 0 3 3 2 2 AAA domain AAA_24 PF13479.1 KKK20903.1 - 6.5e-06 25.8 0.5 0.095 12.2 0.0 2.9 3 0 0 3 3 2 2 AAA domain DUF815 PF05673.8 KKK20903.1 - 9.5e-06 24.7 0.0 0.011 14.6 0.0 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF815) Parvo_NS1 PF01057.12 KKK20903.1 - 1.3e-05 24.2 0.1 0.044 12.6 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 Sigma54_activat PF00158.21 KKK20903.1 - 2.4e-05 23.8 0.1 0.3 10.5 0.0 3.3 2 2 0 2 2 2 2 Sigma-54 interaction domain NACHT PF05729.7 KKK20903.1 - 3.5e-05 23.5 0.1 0.085 12.5 0.0 3.3 3 0 0 3 3 3 1 NACHT domain Arch_ATPase PF01637.13 KKK20903.1 - 4.2e-05 23.3 1.0 5.3 6.6 0.0 4.2 3 2 2 5 5 4 0 Archaeal ATPase Vps4_C PF09336.5 KKK20903.1 - 5.5e-05 22.9 0.0 0.00031 20.5 0.0 2.2 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain Bac_DnaA PF00308.13 KKK20903.1 - 6e-05 22.7 0.0 0.51 9.9 0.0 3.1 3 0 0 3 3 3 2 Bacterial dnaA protein Sigma54_activ_2 PF14532.1 KKK20903.1 - 6.4e-05 23.0 0.0 0.33 11.0 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain ABC_tran PF00005.22 KKK20903.1 - 0.00013 22.3 0.0 0.45 10.8 0.0 3.4 2 1 0 2 2 2 1 ABC transporter PhoH PF02562.11 KKK20903.1 - 0.00017 20.9 0.4 0.52 9.4 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein AAA_3 PF07726.6 KKK20903.1 - 0.00028 20.5 0.0 0.91 9.1 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 KKK20903.1 - 0.0003 20.4 0.0 0.38 10.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_11 PF13086.1 KKK20903.1 - 0.00058 19.4 0.0 1.1 8.7 0.0 2.6 2 1 0 2 2 2 2 AAA domain DUF2075 PF09848.4 KKK20903.1 - 0.0013 17.7 0.0 1.2 8.0 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) NTPase_1 PF03266.10 KKK20903.1 - 0.0015 18.2 0.3 0.64 9.6 0.0 3.7 3 0 0 3 3 3 1 NTPase NB-ARC PF00931.17 KKK20903.1 - 0.0019 17.1 0.1 0.62 8.8 0.0 2.5 2 0 0 2 2 2 1 NB-ARC domain Viral_helicase1 PF01443.13 KKK20903.1 - 0.0042 16.6 0.0 0.29 10.6 0.0 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase KAP_NTPase PF07693.9 KKK20903.1 - 0.008 15.1 0.3 0.92 8.4 0.0 3.2 2 2 2 4 4 4 1 KAP family P-loop domain AAA_10 PF12846.2 KKK20903.1 - 0.01 15.2 0.7 1.6 8.0 0.0 3.6 3 1 1 4 4 4 0 AAA-like domain IPT PF01745.11 KKK20903.1 - 0.013 14.6 0.0 2 7.5 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase Zot PF05707.7 KKK20903.1 - 0.034 13.6 0.2 11 5.3 0.1 3.9 3 1 0 3 3 3 0 Zonular occludens toxin (Zot) T2SE PF00437.15 KKK20903.1 - 0.052 12.4 0.0 5.5 5.8 0.0 2.6 2 0 0 2 2 2 0 Type II/IV secretion system protein SKI PF01202.17 KKK20903.1 - 0.077 12.8 0.1 8 6.3 0.0 2.8 2 0 0 2 2 2 0 Shikimate kinase AFG1_ATPase PF03969.11 KKK20903.1 - 0.083 11.6 0.0 9.8 4.8 0.0 2.3 2 0 0 2 2 2 0 AFG1-like ATPase UPF0079 PF02367.12 KKK20903.1 - 0.091 12.3 0.1 9.2 5.9 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 MobB PF03205.9 KKK20903.1 - 0.093 12.4 0.2 3.5 7.3 0.0 3.1 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B EnY2 PF10163.4 KKK20904.1 - 0.06 13.2 0.0 0.085 12.8 0.0 1.2 1 0 0 1 1 1 0 Transcription factor e(y)2 Pkinase PF00069.20 KKK20907.1 - 1.5e-16 60.3 0.0 9.7e-16 57.6 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK20907.1 - 5.2e-13 48.6 0.0 2.8e-12 46.2 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KKK20907.1 - 0.079 11.9 0.0 0.25 10.2 0.0 1.7 1 1 0 1 1 1 0 Kinase-like Kdo PF06293.9 KKK20907.1 - 0.1 11.6 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family zf-C3HC4_3 PF13920.1 KKK20910.1 - 7.3e-09 35.1 11.7 1.2e-08 34.4 8.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) CFEM PF05730.6 KKK20911.1 - 2.1e-15 56.2 11.5 3.5e-15 55.5 8.0 1.4 1 0 0 1 1 1 1 CFEM domain SOG2 PF10428.4 KKK20911.1 - 2 7.0 13.8 2.2 6.8 9.5 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein DUF566 PF04484.7 KKK20911.1 - 2.2 7.7 10.0 2.5 7.5 7.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF566) Pex14_N PF04695.8 KKK20911.1 - 2.5 8.1 8.5 4.3 7.3 5.9 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF605 PF04652.11 KKK20911.1 - 7.3 5.8 11.9 8.9 5.5 8.3 1.1 1 0 0 1 1 1 0 Vta1 like APH PF01636.18 KKK20912.1 - 9.5e-15 54.9 0.0 2.4e-14 53.6 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 KKK20912.1 - 0.0059 15.7 0.0 0.46 9.5 0.0 2.9 3 0 0 3 3 3 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 KKK20912.1 - 0.0059 16.1 0.0 0.016 14.7 0.0 1.7 2 0 0 2 2 2 1 Choline/ethanolamine kinase DUF1679 PF07914.6 KKK20912.1 - 0.015 13.9 0.0 1.1 7.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) tRNA_int_end_N2 PF12928.2 KKK20913.1 - 5.4e-36 121.8 0.0 1e-35 121.0 0.0 1.5 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term adh_short PF00106.20 KKK20913.1 - 2.3e-24 86.1 0.0 4.3e-14 52.7 0.0 2.5 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.1 KKK20913.1 - 1.3e-10 41.4 0.0 2.1e-10 40.8 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KKK20913.1 - 1.8e-09 37.5 0.0 9.4e-09 35.1 0.0 2.1 1 1 0 1 1 1 1 KR domain tRNA_int_endo_N PF02778.9 KKK20913.1 - 0.012 15.1 0.0 0.026 14.0 0.0 1.4 1 0 0 1 1 1 0 tRNA intron endonuclease, N-terminal domain Shikimate_DH PF01488.15 KKK20913.1 - 0.018 15.1 0.0 0.11 12.6 0.0 2.0 1 1 1 2 2 2 0 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.16 KKK20913.1 - 0.036 13.4 0.1 17 4.7 0.0 3.2 3 0 0 3 3 3 0 NAD dependent epimerase/dehydratase family ThiF PF00899.16 KKK20914.1 - 7.3e-42 142.4 0.0 1.8e-41 141.1 0.0 1.7 1 0 0 1 1 1 1 ThiF family UBACT PF02134.16 KKK20914.1 - 1.6e-29 101.2 0.0 5.4e-29 99.5 0.2 1.8 2 0 0 2 2 2 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 KKK20914.1 - 2.1e-21 75.0 8.0 3.6e-21 74.2 1.5 2.5 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site UAE_UbL PF14732.1 KKK20914.1 - 6.8e-15 54.9 0.5 1.5e-14 53.8 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain NAD_binding_7 PF13241.1 KKK20914.1 - 0.00049 20.3 0.1 0.0022 18.2 0.0 2.2 2 0 0 2 2 2 1 Putative NAD(P)-binding Shikimate_DH PF01488.15 KKK20914.1 - 0.0079 16.2 0.0 0.034 14.2 0.0 2.0 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.22 KKK20914.1 - 0.022 15.1 0.0 1.5 9.3 0.0 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Seryl_tRNA_N PF02403.17 KKK20914.1 - 2.3 8.2 6.4 1.6 8.7 0.0 3.1 2 1 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain DNA_pol_delta_4 PF04081.8 KKK20915.1 - 8e-27 93.9 0.3 1.2e-26 93.4 0.1 1.3 1 1 0 1 1 1 1 DNA polymerase delta, subunit 4 DUF3580 PF12117.3 KKK20915.1 - 0.18 11.7 3.2 0.24 11.3 2.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3580) Protamine_P2 PF00841.14 KKK20915.1 - 0.22 12.0 1.1 0.38 11.3 0.2 1.8 2 0 0 2 2 2 0 Sperm histone P2 RR_TM4-6 PF06459.7 KKK20915.1 - 3.5 7.4 6.4 4.7 7.0 4.4 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Arrestin_C PF02752.17 KKK20916.1 - 1.7e-14 54.1 0.0 7.9e-14 51.9 0.0 2.0 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain NUDIX PF00293.23 KKK20942.1 - 6.1e-25 87.4 0.4 7.7e-25 87.0 0.3 1.1 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.1 KKK20942.1 - 0.047 13.1 0.1 0.085 12.2 0.1 1.4 1 1 0 1 1 1 0 NUDIX domain AdoMet_MTase PF07757.8 KKK20949.1 - 1.1e-34 118.9 0.2 2.3e-33 114.6 0.2 2.3 1 1 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase CorA PF01544.13 KKK20950.1 - 6.2e-08 32.0 0.1 8.7e-08 31.5 0.1 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Sec39 PF08314.6 KKK20950.1 - 0.13 10.1 0.1 0.18 9.6 0.1 1.1 1 0 0 1 1 1 0 Secretory pathway protein Sec39 WH2 PF02205.15 KKK20951.1 - 0.0034 16.9 4.3 0.11 12.0 3.0 2.5 1 1 0 1 1 1 1 WH2 motif ApbA PF02558.11 KKK20952.1 - 2.9e-24 85.2 0.0 4.3e-24 84.6 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 KKK20952.1 - 5.6e-22 78.0 0.0 8.3e-22 77.5 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal DASH_Hsk3 PF08227.6 KKK20953.1 - 9.6e-22 76.9 0.7 1.6e-21 76.1 0.5 1.4 1 0 0 1 1 1 1 DASH complex subunit Hsk3 like BBS2_C PF14782.1 KKK20953.1 - 0.046 12.2 0.0 0.057 11.9 0.0 1.2 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, C-terminal DUF4407 PF14362.1 KKK20953.1 - 0.11 11.4 0.1 0.13 11.1 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Macoilin PF09726.4 KKK20953.1 - 0.55 8.4 3.6 0.54 8.4 2.5 1.1 1 0 0 1 1 1 0 Transmembrane protein His_Phos_1 PF00300.17 KKK20954.1 - 1.8e-31 109.3 0.0 2.2e-31 109.1 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) F-box PF00646.28 KKK20956.1 - 0.026 14.1 0.9 1 9.0 0.0 2.7 2 0 0 2 2 2 0 F-box domain DUF1489 PF07370.6 KKK20956.1 - 0.044 13.3 0.1 0.25 10.8 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1489) BpuSI_N PF15516.1 KKK20956.1 - 0.068 12.8 0.0 0.32 10.6 0.0 1.9 2 0 0 2 2 2 0 BpuSI N-terminal domain Peptidase_C14 PF00656.17 KKK20960.1 - 1.2e-54 185.6 0.0 1.4e-54 185.4 0.0 1.0 1 0 0 1 1 1 1 Caspase domain Methyltransf_16 PF10294.4 KKK20961.1 - 4.8e-14 52.1 0.0 6.6e-14 51.7 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_23 PF13489.1 KKK20961.1 - 0.0013 18.4 0.0 0.0023 17.6 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain KTI12 PF08433.5 KKK20962.1 - 2.1e-62 210.7 0.0 9.4e-62 208.6 0.0 2.0 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.1 KKK20962.1 - 7.1e-06 25.9 0.2 3.2e-05 23.8 0.0 2.1 3 0 0 3 3 3 1 AAA domain PHD PF00628.24 KKK20969.1 - 6.2e-09 35.4 7.5 1e-08 34.7 5.2 1.3 1 0 0 1 1 1 1 PHD-finger DUF1423 PF07227.6 KKK20969.1 - 0.93 8.0 2.2 1.4 7.5 1.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1423) PHD_2 PF13831.1 KKK20969.1 - 1 8.7 5.0 1.7 8.0 3.5 1.4 1 0 0 1 1 1 0 PHD-finger DUF2293 PF10056.4 KKK20970.1 - 5.6e-31 106.3 0.1 5.6e-31 106.3 0.0 2.4 4 0 0 4 4 4 1 Uncharacterized conserved protein (DUF2293) MFS_1 PF07690.11 KKK20971.1 - 1e-28 100.1 24.3 1.4e-28 99.6 14.2 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF718 PF05336.8 KKK20971.1 - 6.8e-13 48.3 0.1 1.2e-12 47.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF718) NIR_SIR PF01077.17 KKK20972.1 - 2.9e-30 104.6 0.0 6.7e-30 103.5 0.0 1.6 1 0 0 1 1 1 1 Nitrite and sulphite reductase 4Fe-4S domain Pyr_redox_2 PF07992.9 KKK20972.1 - 3.9e-27 95.4 0.2 8.8e-27 94.2 0.1 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KKK20972.1 - 1.4e-17 63.8 2.1 2.9e-16 59.6 0.2 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Fer2_BFD PF04324.10 KKK20972.1 - 2.9e-14 52.8 4.3 1.2e-12 47.6 2.2 2.7 2 0 0 2 2 2 1 BFD-like [2Fe-2S] binding domain Rieske_2 PF13806.1 KKK20972.1 - 6.5e-12 45.0 0.0 1.5e-11 43.9 0.0 1.6 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain NIR_SIR_ferr PF03460.12 KKK20972.1 - 9.4e-12 44.3 0.0 2e-11 43.3 0.0 1.6 1 0 0 1 1 1 1 Nitrite/Sulfite reductase ferredoxin-like half domain Rieske PF00355.21 KKK20972.1 - 1.3e-11 43.8 0.0 4.5e-11 42.1 0.0 1.9 2 0 0 2 2 2 1 Rieske [2Fe-2S] domain Pyr_redox_3 PF13738.1 KKK20972.1 - 0.00091 19.3 0.0 0.005 16.9 0.0 2.3 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KKK20972.1 - 0.0076 16.0 1.6 6.2 6.5 0.0 3.5 4 0 0 4 4 4 1 FAD-NAD(P)-binding HI0933_like PF03486.9 KKK20972.1 - 0.014 13.9 0.0 1.2 7.5 0.0 2.5 3 0 0 3 3 3 0 HI0933-like protein Phosphorylase PF00343.15 KKK20973.1 - 0 1068.2 0.2 0 1068.0 0.2 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase zf-C2HC_2 PF13913.1 KKK20973.1 - 0.45 10.2 1.9 22 4.8 0.1 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type ABC_membrane_2 PF06472.10 KKK20974.1 - 8.5e-112 372.8 0.8 8.5e-112 372.8 0.6 1.4 2 0 0 2 2 2 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 KKK20974.1 - 1.7e-17 63.9 0.0 3.3e-17 63.0 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 KKK20974.1 - 0.0001 22.3 0.0 0.00031 20.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 KKK20974.1 - 0.01 15.3 0.0 0.027 13.9 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.1 KKK20974.1 - 0.013 15.7 0.0 0.027 14.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 KKK20974.1 - 0.024 14.6 0.1 0.096 12.6 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain SMC_N PF02463.14 KKK20974.1 - 0.043 13.0 0.0 0.11 11.7 0.0 1.6 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain DUF258 PF03193.11 KKK20974.1 - 0.13 11.4 0.0 0.28 10.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Pkinase PF00069.20 KKK20975.1 - 3.7e-72 242.5 0.0 4.5e-72 242.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK20975.1 - 3.3e-30 105.0 0.0 4.1e-30 104.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KKK20975.1 - 3.4e-05 23.0 0.0 0.00012 21.2 0.0 1.8 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KKK20975.1 - 0.00026 20.0 0.0 0.062 12.2 0.0 2.2 1 1 1 2 2 2 2 Kinase-like APH PF01636.18 KKK20975.1 - 0.00053 19.7 0.0 0.0018 18.0 0.0 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 KKK20975.1 - 0.05 12.9 0.0 0.077 12.3 0.0 1.3 1 0 0 1 1 1 0 RIO1 family LEA_6 PF10714.4 KKK20975.1 - 0.11 12.3 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Late embryogenesis abundant protein 18 G-alpha PF00503.15 KKK20976.1 - 1.2e-123 412.6 0.1 1.5e-123 412.3 0.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 KKK20976.1 - 5.3e-15 55.0 0.2 4.4e-10 39.0 0.0 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KKK20976.1 - 0.00046 19.4 0.1 0.8 8.7 0.0 2.2 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Miro PF08477.8 KKK20976.1 - 0.0019 18.6 0.0 0.74 10.3 0.0 2.7 3 0 0 3 3 3 2 Miro-like protein AAA_29 PF13555.1 KKK20976.1 - 0.054 13.0 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain FTA4 PF13093.1 KKK20977.1 - 2.9e-41 141.2 8.7 3.8e-41 140.8 6.1 1.1 1 0 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 DUF3584 PF12128.3 KKK20977.1 - 0.00044 17.7 5.2 0.0005 17.5 3.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) CR6_interact PF10147.4 KKK20977.1 - 0.022 14.1 0.2 0.022 14.1 0.2 1.7 1 1 0 1 1 1 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 Transcrip_act PF04949.8 KKK20977.1 - 0.073 12.7 0.6 0.25 10.9 0.1 1.8 1 1 1 2 2 2 0 Transcriptional activator Musclin PF11037.3 KKK20977.1 - 0.083 12.5 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Insulin-resistance promoting peptide in skeletal muscle ALIX_LYPXL_bnd PF13949.1 KKK20977.1 - 0.13 11.1 7.0 0.22 10.4 4.9 1.3 1 1 0 1 1 1 0 ALIX V-shaped domain binding to HIV DUF3510 PF12022.3 KKK20977.1 - 0.16 12.0 0.8 0.26 11.4 0.1 1.7 2 1 0 2 2 2 0 Domain of unknown function (DUF3510) Hrs_helical PF12210.3 KKK20977.1 - 0.33 11.2 7.6 0.9 9.8 1.8 2.8 2 1 1 3 3 3 0 Hepatocyte growth factor-regulated tyrosine kinase substrate Mnd1 PF03962.10 KKK20977.1 - 0.42 10.2 4.9 1.4 8.5 2.2 2.0 1 1 1 2 2 2 0 Mnd1 family Med21 PF11221.3 KKK20977.1 - 1.1 9.1 6.9 0.15 11.9 1.7 1.8 2 0 0 2 2 2 0 Subunit 21 of Mediator complex Lipoprotein_20 PF13942.1 KKK20977.1 - 1.2 8.6 7.1 0.97 8.9 3.9 1.6 1 1 0 1 1 1 0 YfhG lipoprotein CENP-H PF05837.7 KKK20978.1 - 0.043 13.9 1.6 0.1 12.7 1.1 1.6 1 0 0 1 1 1 0 Centromere protein H (CENP-H) SlyX PF04102.7 KKK20978.1 - 0.06 13.7 3.6 0.086 13.2 0.2 2.7 3 0 0 3 3 3 0 SlyX GlutR_dimer PF00745.15 KKK20978.1 - 0.12 12.2 1.7 0.2 11.6 0.4 1.9 2 0 0 2 2 2 0 Glutamyl-tRNAGlu reductase, dimerisation domain LRR_6 PF13516.1 KKK20979.1 - 0.00094 19.0 0.8 1.5e+02 2.9 0.0 7.0 8 0 0 8 8 8 0 Leucine Rich repeat LRR_4 PF12799.2 KKK20979.1 - 0.01 15.4 7.7 0.073 12.7 0.0 5.1 6 1 1 7 7 7 0 Leucine Rich repeats (2 copies) Ribosomal_L18p PF00861.17 KKK20980.1 - 7.9e-43 145.4 0.2 7.9e-43 145.4 0.1 1.9 2 0 0 2 2 2 1 Ribosomal L18p/L5e family Ribosomal_L18_c PF14204.1 KKK20980.1 - 1.1e-32 112.4 7.8 1.1e-32 112.4 5.4 2.0 3 0 0 3 3 3 1 Ribosomal L18 C-terminal region HAD_2 PF13419.1 KKK20980.1 - 1.2e-15 58.2 0.5 9.1e-15 55.3 0.0 2.5 3 0 0 3 3 3 1 Haloacid dehalogenase-like hydrolase Metal_resist PF13801.1 KKK20980.1 - 0.074 13.0 0.0 0.2 11.6 0.0 1.7 1 0 0 1 1 1 0 Heavy-metal resistance Mit_KHE1 PF10173.4 KKK20981.1 - 1.1e-66 224.2 1.2 1.5e-66 223.8 0.8 1.1 1 0 0 1 1 1 1 Mitochondrial K+-H+ exchange-related DUF4478 PF14793.1 KKK20981.1 - 0.13 11.8 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4478) End3 PF12761.2 KKK20982.1 - 3.1e-73 245.5 0.9 4.5e-73 245.0 0.6 1.2 1 0 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 EF-hand_4 PF12763.2 KKK20982.1 - 2e-51 172.0 0.2 4.2e-48 161.3 0.1 2.3 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.27 KKK20982.1 - 4.8e-09 34.8 0.2 1.3e-07 30.3 0.2 2.7 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 KKK20982.1 - 1e-06 28.2 0.2 3.5e-05 23.3 0.1 2.5 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 KKK20982.1 - 2.5e-06 26.8 0.3 0.00027 20.5 0.2 2.9 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.1 KKK20982.1 - 4e-06 26.8 0.3 5.8e-05 23.1 0.0 2.7 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_5 PF13202.1 KKK20982.1 - 0.0006 19.0 0.2 0.002 17.3 0.1 1.9 1 0 0 1 1 1 1 EF hand Rabaptin PF03528.10 KKK20982.1 - 0.041 13.8 3.1 0.093 12.6 1.7 1.9 2 0 0 2 2 2 0 Rabaptin Phlebovirus_NSM PF07246.6 KKK20982.1 - 0.54 9.3 3.3 0.85 8.7 2.3 1.3 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M Cupin_2 PF07883.6 KKK20983.1 - 2.9e-08 33.0 0.7 4.5e-08 32.4 0.5 1.2 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.17 KKK20983.1 - 9.5e-08 31.5 0.1 1.2e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 Cupin ARD PF03079.9 KKK20983.1 - 2.5e-05 24.2 0.0 3.5e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 ARD/ARD' family Cupin_6 PF12852.2 KKK20983.1 - 7e-05 22.5 0.0 8.1e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.14 KKK20983.1 - 0.045 13.4 0.1 0.063 12.9 0.1 1.3 1 0 0 1 1 1 0 AraC-like ligand binding domain DUF588 PF04535.7 KKK20984.1 - 0.026 14.0 1.1 0.05 13.1 0.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF588) Ilm1 PF10311.4 KKK20984.1 - 0.079 12.4 0.3 0.12 11.8 0.2 1.4 1 1 0 1 1 1 0 Increased loss of mitochondrial DNA protein 1 Aminotran_3 PF00202.16 KKK20985.1 - 2.8e-87 292.7 0.0 3.3e-87 292.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III DSPc PF00782.15 KKK20986.1 - 1.1e-07 31.4 0.0 1.6e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.7 KKK20986.1 - 0.017 14.0 0.0 0.022 13.6 0.0 1.1 1 0 0 1 1 1 0 Initiator tRNA phosphoribosyl transferase SNF2_N PF00176.18 KKK20987.1 - 4.3e-68 229.2 0.5 1.2e-67 227.8 0.1 1.9 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KKK20987.1 - 2.2e-16 59.5 0.0 2e-15 56.4 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 KKK20987.1 - 0.018 15.2 0.1 7.6 6.6 0.0 2.9 2 1 0 2 2 2 0 AAA domain Avl9 PF09794.4 KKK20989.1 - 2.5e-139 463.9 0.1 9.3e-123 409.4 0.0 2.2 2 0 0 2 2 2 2 Transport protein Avl9 SPA PF08616.5 KKK20989.1 - 5e-10 39.0 0.1 3.2e-05 23.5 0.0 2.4 2 0 0 2 2 2 2 Stabilization of polarity axis DUF2347 PF09804.4 KKK20989.1 - 0.013 14.8 0.3 0.013 14.8 0.2 3.2 3 1 0 3 3 3 0 Uncharacterized conserved protein (DUF2347) Cullin PF00888.17 KKK20990.1 - 1.2e-205 684.5 11.9 1.2e-205 684.5 8.2 1.3 2 0 0 2 2 2 1 Cullin family Cullin_Nedd8 PF10557.4 KKK20990.1 - 1.5e-27 95.2 3.4 1.5e-27 95.2 2.4 3.5 3 0 0 3 3 3 1 Cullin protein neddylation domain TipAS PF07739.8 KKK20990.1 - 0.0072 16.6 0.3 0.14 12.4 0.0 3.2 3 0 0 3 3 3 1 TipAS antibiotic-recognition domain WGG PF10273.4 KKK20990.1 - 0.15 12.1 3.4 24 5.1 0.0 4.2 6 0 0 6 6 6 0 Pre-rRNA-processing protein TSR2 DUF4210 PF13915.1 KKK20991.1 - 4.6e-26 90.8 0.2 2e-25 88.8 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4210) Chromosome_seg PF13889.1 KKK20991.1 - 5e-23 80.7 0.4 1.4e-22 79.3 0.3 1.8 1 0 0 1 1 1 1 Chromosome segregation during meiosis rRNA_processing PF08524.6 KKK20992.1 - 0.99 9.1 19.6 0.06 13.1 2.2 2.5 2 1 0 2 2 2 0 rRNA processing Sec5 PF15469.1 KKK20993.1 - 5.1e-34 117.5 0.0 1.6e-33 115.9 0.0 1.9 2 0 0 2 2 2 1 Exocyst complex component Sec5 Vps51 PF08700.6 KKK20993.1 - 8.6e-06 25.5 0.1 4.2e-05 23.3 0.1 2.2 1 0 0 1 1 1 1 Vps51/Vps67 DUF4111 PF13427.1 KKK20993.1 - 0.08 12.7 0.0 0.26 11.1 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4111) Iso_dh PF00180.15 KKK20994.1 - 1.5e-89 300.3 0.0 1.7e-64 218.0 0.0 2.0 1 1 1 2 2 2 2 Isocitrate/isopropylmalate dehydrogenase HHH_2 PF12826.2 KKK20994.1 - 0.011 15.5 0.1 0.13 12.1 0.0 2.2 2 0 0 2 2 2 0 Helix-hairpin-helix motif Eaf7 PF07904.8 KKK20995.1 - 2.7e-30 104.1 0.0 2.7e-30 104.1 0.0 1.9 2 0 0 2 2 1 1 Chromatin modification-related protein EAF7 Nop14 PF04147.7 KKK20995.1 - 0.00061 17.8 15.9 0.00071 17.6 11.0 1.1 1 0 0 1 1 1 1 Nop14-like family Prothymosin PF03247.9 KKK20995.1 - 0.0092 16.1 27.6 0.02 15.0 19.1 1.5 1 0 0 1 1 1 1 Prothymosin/parathymosin family Daxx PF03344.10 KKK20995.1 - 0.035 12.6 20.9 0.06 11.8 14.5 1.3 1 0 0 1 1 1 0 Daxx Family TFIIF_alpha PF05793.7 KKK20995.1 - 0.044 12.1 15.6 0.06 11.7 10.8 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) TFIIA PF03153.8 KKK20995.1 - 0.13 12.1 18.9 0.1 12.5 10.2 2.0 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit PAXIP1_C PF15364.1 KKK20995.1 - 0.35 10.7 11.0 0.91 9.4 7.6 1.6 1 0 0 1 1 1 0 PAXIP1-associated-protein-1 C term PTIP binding protein NOA36 PF06524.7 KKK20995.1 - 0.69 9.1 15.3 0.99 8.5 10.6 1.2 1 0 0 1 1 1 0 NOA36 protein PPP4R2 PF09184.6 KKK20995.1 - 0.74 9.3 14.1 1 8.8 9.8 1.2 1 0 0 1 1 1 0 PPP4R2 CDC45 PF02724.9 KKK20995.1 - 0.8 7.6 20.5 1 7.3 14.2 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF3381 PF11861.3 KKK20995.1 - 1.2 8.6 8.6 20 4.6 6.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) Cwf_Cwc_15 PF04889.7 KKK20995.1 - 1.8 8.2 15.8 2.8 7.5 11.0 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Nop53 PF07767.6 KKK20995.1 - 2.8 6.8 15.9 3.3 6.5 8.8 2.1 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) BTV_NS2 PF04514.7 KKK20995.1 - 3.2 6.5 9.0 4.9 5.9 6.2 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 BUD22 PF09073.5 KKK20995.1 - 3.4 6.6 18.2 5.5 5.9 12.6 1.4 1 0 0 1 1 1 0 BUD22 Pox_Ag35 PF03286.9 KKK20995.1 - 5.5 6.4 10.8 9.7 5.6 7.5 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein SDA1 PF05285.7 KKK20995.1 - 5.8 6.0 21.9 9.3 5.4 15.2 1.2 1 0 0 1 1 1 0 SDA1 Spc97_Spc98 PF04130.8 KKK20996.1 - 3.5e-78 263.2 4.4 4.4e-78 262.9 3.0 1.1 1 0 0 1 1 1 1 Spc97 / Spc98 family NAD_binding_1 PF00175.16 KKK20997.1 - 1.3e-28 99.6 0.0 1.6e-28 99.4 0.0 1.1 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 KKK20997.1 - 5.6e-06 26.3 0.0 0.087 12.7 0.0 2.1 1 1 1 2 2 2 2 Ferric reductase NAD binding domain Mo-co_dimer PF03404.11 KKK20998.1 - 1.7e-56 189.4 0.0 3.2e-56 188.5 0.0 1.5 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Oxidored_molyb PF00174.14 KKK20998.1 - 1e-43 148.6 0.0 1.8e-43 147.8 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain FAD_binding_6 PF00970.19 KKK20998.1 - 4.4e-30 103.7 0.0 7.4e-30 102.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Cyt-b5 PF00173.23 KKK20998.1 - 2.2e-13 49.8 0.0 4.3e-13 48.8 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Thioredoxin_4 PF13462.1 KKK20998.1 - 0.14 12.1 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin AF-4 PF05110.8 KKK21011.1 - 0.27 9.0 8.8 0.32 8.8 6.1 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein SKG6 PF08693.5 KKK21011.1 - 0.35 10.2 4.6 1.2 8.5 3.2 2.0 1 1 0 1 1 1 0 Transmembrane alpha-helix domain CcmD PF04995.9 KKK21011.1 - 1.6 8.4 4.1 0.27 10.9 0.2 1.7 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) AP_endonuc_2 PF01261.19 KKK21012.1 - 3.8e-13 49.2 0.3 7e-13 48.3 0.2 1.5 1 1 0 1 1 1 1 Xylose isomerase-like TIM barrel Zn_clus PF00172.13 KKK21013.1 - 1.9e-09 37.2 12.4 3.1e-09 36.5 8.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aa_trans PF01490.13 KKK21014.1 - 2.8e-60 203.9 16.1 1.1e-52 178.9 5.8 2.0 1 1 1 2 2 2 2 Transmembrane amino acid transporter protein Claudin_2 PF13903.1 KKK21014.1 - 0.0063 16.2 0.7 0.52 9.9 0.6 2.7 3 0 0 3 3 3 1 PMP-22/EMP/MP20/Claudin tight junction adh_short_C2 PF13561.1 KKK21015.1 - 1.2e-13 51.4 0.0 4e-12 46.4 0.0 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KKK21015.1 - 2.7e-13 50.1 0.4 4.3e-13 49.5 0.3 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KKK21015.1 - 9.2e-06 25.4 0.2 1.5e-05 24.7 0.1 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 KKK21015.1 - 0.024 13.5 0.0 0.033 13.1 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein RTA1 PF04479.8 KKK21016.1 - 4.1e-17 62.4 2.2 6.9e-17 61.6 1.5 1.3 1 0 0 1 1 1 1 RTA1 like protein MerC PF03203.9 KKK21016.1 - 0.77 10.1 5.1 4.8 7.5 3.5 2.4 1 1 0 1 1 1 0 MerC mercury resistance protein CoA_binding_3 PF13727.1 KKK21016.1 - 2.9 7.6 7.8 7.9 6.2 2.5 2.2 2 0 0 2 2 2 0 CoA-binding domain Zn_clus PF00172.13 KKK21019.1 - 7e-08 32.2 10.7 1.3e-07 31.4 7.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KKK21019.1 - 3.9e-07 29.2 1.7 6.7e-07 28.4 1.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DSPc PF00782.15 KKK21020.1 - 0.0018 17.8 0.0 0.0024 17.4 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain BDHCT PF08072.6 KKK21020.1 - 0.12 12.5 0.1 0.68 10.0 0.1 2.1 2 0 0 2 2 2 0 BDHCT (NUC031) domain AA_permease_2 PF13520.1 KKK21021.1 - 5.7e-48 163.5 43.5 7.1e-48 163.1 30.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KKK21021.1 - 1.3e-23 83.0 39.0 1.8e-23 82.6 27.0 1.1 1 0 0 1 1 1 1 Amino acid permease HbrB PF08539.6 KKK21040.1 - 8.8e-60 201.1 0.0 1.3e-59 200.5 0.0 1.3 1 0 0 1 1 1 1 HbrB-like Gon7 PF08738.5 KKK21041.1 - 1.1e-19 70.3 1.6 3.8e-18 65.3 1.1 2.0 1 1 0 1 1 1 1 Gon7 family 6PF2K PF01591.13 KKK21042.1 - 2.6e-76 255.5 0.2 6.5e-76 254.2 0.0 1.7 2 0 0 2 2 2 1 6-phosphofructo-2-kinase Vps39_2 PF10367.4 KKK21042.1 - 1.2e-34 118.7 0.2 5.2e-34 116.6 0.0 2.3 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.4 KKK21042.1 - 7.4e-34 116.0 0.0 6.6e-32 109.7 0.0 2.7 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 His_Phos_1 PF00300.17 KKK21042.1 - 1.8e-33 115.8 0.0 4e-33 114.7 0.0 1.6 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) CNH PF00780.17 KKK21042.1 - 1.5e-18 67.2 0.0 5.7e-18 65.3 0.0 1.8 1 1 0 1 1 1 1 CNH domain AAA_33 PF13671.1 KKK21042.1 - 9e-07 28.8 0.0 2.1e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 KKK21042.1 - 0.0001 21.6 0.0 0.00026 20.3 0.0 1.6 1 0 0 1 1 1 1 Chromatin associated protein KTI12 Clathrin PF00637.15 KKK21042.1 - 0.00038 20.0 0.6 0.00038 20.0 0.4 2.6 3 0 0 3 3 3 1 Region in Clathrin and VPS TPR_1 PF00515.23 KKK21042.1 - 0.28 10.8 1.9 29 4.4 0.6 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat AAA PF00004.24 KKK21043.1 - 1.9e-16 60.4 0.0 6.7e-16 58.6 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 KKK21043.1 - 2.4e-05 24.0 0.1 7e-05 22.4 0.1 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 KKK21043.1 - 0.00014 22.0 0.9 0.003 17.7 0.6 2.8 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KKK21043.1 - 0.00052 19.7 0.0 0.0016 18.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KKK21043.1 - 0.0082 16.1 3.5 0.016 15.2 0.0 2.8 3 0 0 3 3 3 1 AAA ATPase domain AAA_33 PF13671.1 KKK21043.1 - 0.031 14.1 1.3 0.067 13.0 0.0 2.3 2 1 0 2 2 2 0 AAA domain AAA_17 PF13207.1 KKK21043.1 - 0.038 14.7 2.9 0.063 14.1 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.1 KKK21043.1 - 0.41 10.9 0.0 0.41 10.9 0.0 3.1 3 1 1 4 4 4 0 AAA domain Myb_DNA-bind_5 PF13873.1 KKK21044.1 - 0.00018 21.3 0.4 0.042 13.7 0.0 2.8 2 1 1 3 3 3 1 Myb/SANT-like DNA-binding domain Ribosomal_60s PF00428.14 KKK21044.1 - 0.031 14.6 9.0 0.031 14.6 6.2 2.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein PTSIIB_sorb PF03830.10 KKK21044.1 - 0.089 12.6 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 PTS system sorbose subfamily IIB component RAP1 PF07218.6 KKK21044.1 - 0.25 9.3 2.2 0.3 9.1 1.5 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Gly-zipper_OmpA PF13436.1 KKK21044.1 - 0.61 9.7 13.9 0.087 12.4 6.2 2.0 2 0 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain Pyr_redox_3 PF13738.1 KKK21046.1 - 2.4e-30 106.1 0.1 3.9e-30 105.4 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KKK21046.1 - 4.5e-22 77.9 0.5 3.4e-21 75.0 0.2 2.3 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 KKK21046.1 - 3.3e-11 42.6 1.1 2.2e-08 33.4 0.1 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 KKK21046.1 - 1.1e-09 38.1 0.0 3.1e-09 36.7 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KKK21046.1 - 3.2e-09 36.9 0.0 9.9e-09 35.3 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KKK21046.1 - 2.2e-07 30.1 0.4 3.3e-05 22.9 0.0 2.6 3 0 0 3 3 3 2 FAD dependent oxidoreductase Shikimate_DH PF01488.15 KKK21046.1 - 6.4e-06 26.3 0.1 0.21 11.6 0.0 2.9 3 0 0 3 3 3 2 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.22 KKK21046.1 - 2.3e-05 24.7 0.9 0.57 10.6 0.4 3.3 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KKK21046.1 - 0.00027 20.0 0.1 0.0014 17.7 0.0 2.0 2 0 0 2 2 2 1 Thi4 family NAD_binding_9 PF13454.1 KKK21046.1 - 0.00034 20.4 1.4 0.0053 16.5 0.0 3.3 4 1 0 4 4 4 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 KKK21046.1 - 0.0006 18.7 0.1 0.00095 18.1 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_7 PF13241.1 KKK21046.1 - 0.0017 18.5 0.0 0.17 12.1 0.1 2.6 2 1 0 2 2 2 1 Putative NAD(P)-binding HI0933_like PF03486.9 KKK21046.1 - 0.037 12.5 2.1 0.061 11.7 0.3 2.1 2 0 0 2 2 2 0 HI0933-like protein AA_permease PF00324.16 KKK21047.1 - 1.1e-100 337.2 36.4 1.4e-100 336.9 25.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KKK21047.1 - 5.8e-32 110.7 40.3 6.7e-32 110.5 28.0 1.0 1 0 0 1 1 1 1 Amino acid permease Peptidase_S28 PF05577.7 KKK21048.1 - 4.1e-45 154.1 0.0 2.9e-44 151.3 0.0 1.9 1 1 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S9 PF00326.16 KKK21048.1 - 0.069 12.3 0.1 0.11 11.6 0.1 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family DUF2457 PF10446.4 KKK21048.1 - 1.1 7.9 4.4 1.5 7.4 3.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Utp8 PF10395.4 KKK21049.1 - 0.021 13.1 0.2 1.8 6.7 0.1 2.2 2 0 0 2 2 2 0 Utp8 family Fungal_trans PF04082.13 KKK21050.1 - 5.4e-21 74.6 0.1 1e-20 73.7 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 KKK21050.1 - 1.2e-08 34.8 15.4 0.00026 21.1 1.1 3.4 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KKK21050.1 - 1.3e-06 28.4 5.9 1.3e-06 28.4 4.1 3.3 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 KKK21050.1 - 3.5e-05 23.8 16.2 0.05 13.9 2.2 3.8 3 0 0 3 3 3 2 C2H2-type zinc finger DUF4072 PF13284.1 KKK21050.1 - 0.029 14.5 1.8 0.092 12.9 1.3 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4072) zf-C2H2_jaz PF12171.3 KKK21050.1 - 8.5 6.6 5.4 3.7 7.7 0.8 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding AAA PF00004.24 KKK21051.1 - 3e-09 37.1 0.0 1.7e-08 34.7 0.0 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KKK21051.1 - 2.3e-06 27.7 0.0 1.2e-05 25.4 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KKK21051.1 - 0.00011 22.2 0.0 0.00028 20.9 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain Rad17 PF03215.10 KKK21051.1 - 0.00019 20.2 0.2 0.002 16.9 0.0 2.6 3 0 0 3 3 3 1 Rad17 cell cycle checkpoint protein AAA_17 PF13207.1 KKK21051.1 - 0.0045 17.8 0.1 0.02 15.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 KKK21051.1 - 0.0099 14.9 0.0 0.017 14.1 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 KKK21051.1 - 0.018 14.7 0.0 0.042 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) TIP49 PF06068.8 KKK21051.1 - 0.02 13.6 0.0 0.038 12.7 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus AAA_14 PF13173.1 KKK21051.1 - 0.057 13.3 0.0 0.78 9.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.8 KKK21051.1 - 0.061 12.2 0.0 0.14 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_19 PF13245.1 KKK21051.1 - 0.13 12.0 0.0 0.33 10.7 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain T2SE PF00437.15 KKK21051.1 - 0.2 10.5 0.0 0.34 9.7 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Ala_racemase_N PF01168.15 KKK21068.1 - 1.9e-24 86.4 0.2 2.3e-24 86.1 0.1 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain D-ser_dehydrat PF14031.1 KKK21068.1 - 7.2e-19 67.7 0.0 1.4e-18 66.8 0.0 1.5 1 0 0 1 1 1 1 Putative serine dehydratase domain SDH_alpha PF03313.10 KKK21068.1 - 0.0047 15.9 0.4 0.22 10.5 0.3 2.1 2 0 0 2 2 2 2 Serine dehydratase alpha chain Pkinase PF00069.20 KKK21069.1 - 1.2e-23 83.6 0.0 2.7e-23 82.4 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK21069.1 - 2.2e-07 30.2 0.0 3.7e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KKK21069.1 - 0.014 14.4 0.2 0.023 13.7 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ABC2_membrane PF01061.19 KKK21071.1 - 1.8e-82 275.5 62.3 2.4e-43 147.7 17.5 3.2 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 KKK21071.1 - 4.1e-36 124.3 0.0 1.1e-16 61.3 0.0 3.2 3 0 0 3 3 3 2 ABC transporter PDR_CDR PF06422.7 KKK21071.1 - 2.3e-31 107.5 1.9 7.4e-26 89.8 0.0 3.0 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.1 KKK21071.1 - 9.2e-16 57.7 0.3 3.1e-15 56.0 0.0 2.0 2 0 0 2 2 1 1 ABC-transporter extracellular N-terminal ABC2_membrane_3 PF12698.2 KKK21071.1 - 4.4e-08 32.5 42.5 9.1e-05 21.6 16.1 2.8 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_25 PF13481.1 KKK21071.1 - 4.6e-08 32.6 0.0 0.00089 18.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 KKK21071.1 - 0.00017 22.3 0.0 0.46 11.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 KKK21071.1 - 0.0002 20.5 0.1 0.0011 18.1 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_33 PF13671.1 KKK21071.1 - 0.00031 20.6 0.0 0.13 12.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 KKK21071.1 - 0.00041 19.8 1.6 0.013 15.0 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.1 KKK21071.1 - 0.00049 20.1 1.3 0.03 14.3 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain Zeta_toxin PF06414.7 KKK21071.1 - 0.00055 19.0 0.0 0.0013 17.8 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin cobW PF02492.14 KKK21071.1 - 0.00059 19.3 2.0 0.0012 18.3 0.0 2.1 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_19 PF13245.1 KKK21071.1 - 0.005 16.5 0.4 1.3 8.7 0.0 2.6 2 0 0 2 2 2 1 Part of AAA domain AAA_22 PF13401.1 KKK21071.1 - 0.019 15.1 0.2 0.8 9.8 0.1 3.1 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.1 KKK21071.1 - 0.021 15.1 0.1 0.35 11.1 0.0 2.7 3 0 0 3 3 3 0 AAA domain AAA_23 PF13476.1 KKK21071.1 - 0.032 14.5 0.0 1.3 9.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 KKK21071.1 - 0.044 13.4 1.4 2.9 7.5 0.2 2.5 2 0 0 2 2 2 0 NACHT domain AAA_21 PF13304.1 KKK21071.1 - 0.068 13.1 0.0 0.73 9.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.14 KKK21071.1 - 0.17 11.0 0.2 5.4 6.1 0.0 2.7 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_10 PF12846.2 KKK21071.1 - 0.37 10.1 2.2 9.9 5.4 0.1 2.5 2 0 0 2 2 2 0 AAA-like domain UPF0079 PF02367.12 KKK21071.1 - 0.54 9.8 3.1 1.8 8.1 0.2 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 DUF4646 PF15496.1 KKK21072.1 - 0.00087 19.3 0.9 0.0037 17.3 0.6 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4646) Acetyltransf_1 PF00583.19 KKK21073.1 - 2.4e-14 53.1 0.1 3.8e-14 52.4 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 KKK21073.1 - 1.2e-07 31.3 0.0 2.1e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 KKK21073.1 - 0.0023 18.0 0.0 0.0036 17.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KKK21073.1 - 0.0094 15.8 0.2 0.017 14.9 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KKK21073.1 - 0.046 13.8 0.0 0.074 13.2 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF3749 PF12568.3 KKK21073.1 - 0.15 11.6 1.0 0.19 11.3 0.0 1.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Pkinase PF00069.20 KKK21074.1 - 1.6e-09 37.2 0.0 3e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain HEAT PF02985.17 KKK21074.1 - 5.1e-08 32.3 3.2 0.086 12.9 0.0 5.3 5 0 0 5 5 5 2 HEAT repeat Pkinase_Tyr PF07714.12 KKK21074.1 - 1.3e-06 27.7 0.0 2.4e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT_EZ PF13513.1 KKK21074.1 - 2.1e-05 24.8 0.1 0.025 15.0 0.0 3.0 2 0 0 2 2 2 2 HEAT-like repeat HEAT_2 PF13646.1 KKK21074.1 - 0.0043 17.2 0.0 0.28 11.4 0.0 2.9 1 1 3 4 4 4 2 HEAT repeats Kinase-like PF14531.1 KKK21074.1 - 0.067 12.1 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Cnd1 PF12717.2 KKK21074.1 - 0.14 12.0 0.0 0.38 10.5 0.0 1.6 1 1 1 2 2 2 0 non-SMC mitotic condensation complex subunit 1 FAD_binding_4 PF01565.18 KKK21076.1 - 1.4e-24 86.1 3.2 2.3e-24 85.4 2.2 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KKK21076.1 - 0.067 13.1 0.1 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Berberine and berberine like AIP3 PF03915.8 KKK21077.1 - 5.1e-161 536.3 3.8 5.1e-161 536.3 2.6 1.9 3 0 0 3 3 3 1 Actin interacting protein 3 Lectin_N PF03954.9 KKK21077.1 - 0.00059 19.2 2.0 0.00071 18.9 0.1 2.2 2 0 0 2 2 2 1 Hepatic lectin, N-terminal domain Syntaxin_2 PF14523.1 KKK21077.1 - 0.02 14.9 5.4 2.3 8.2 0.0 3.2 3 0 0 3 3 3 0 Syntaxin-like protein DUF3138 PF11336.3 KKK21077.1 - 0.11 10.6 4.2 0.038 12.1 0.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) DUF1664 PF07889.7 KKK21077.1 - 3.9 7.2 7.8 1.4 8.7 0.9 3.2 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) LsmAD PF06741.8 KKK21078.1 - 4.6e-27 93.9 3.8 1.1e-26 92.6 2.6 1.7 1 0 0 1 1 1 1 LsmAD domain SM-ATX PF14438.1 KKK21078.1 - 2.6e-17 62.5 0.0 5.4e-17 61.4 0.0 1.6 1 0 0 1 1 1 1 Ataxin 2 SM domain Fungal_trans PF04082.13 KKK21079.1 - 9.9e-07 27.8 0.3 9.9e-07 27.8 0.2 1.8 2 1 1 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK21079.1 - 2.3e-06 27.3 8.2 4.4e-06 26.4 5.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain UPF0261 PF06792.6 KKK21080.1 - 3.7e-141 470.2 1.6 5e-141 469.8 1.1 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0261) TIM-br_sig_trns PF09370.5 KKK21080.1 - 1.3e-133 444.0 0.6 2.5e-133 443.1 0.4 1.5 1 0 0 1 1 1 1 TIM-barrel signal transduction protein NMO PF03060.10 KKK21080.1 - 0.01 15.0 0.1 0.02 14.0 0.0 1.4 1 0 0 1 1 1 1 Nitronate monooxygenase Ssu72 PF04722.8 KKK21081.1 - 4.7e-84 280.5 0.0 5.6e-84 280.3 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein Mito_fiss_reg PF05308.6 KKK21081.1 - 0.11 11.9 3.9 0.16 11.3 2.7 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.14 KKK21081.1 - 3.3 6.9 9.3 5.8 6.1 6.4 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Isochorismatase PF00857.15 KKK21082.1 - 1.6e-22 80.2 0.1 2.9e-22 79.4 0.1 1.4 1 1 0 1 1 1 1 Isochorismatase family RNase_PH PF01138.16 KKK21083.1 - 2.8e-31 108.5 1.3 6.3e-31 107.4 0.4 1.8 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 SNF2_N PF00176.18 KKK21084.1 - 1e-53 182.0 0.2 1.8e-53 181.2 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain VIGSSK PF14773.1 KKK21084.1 - 1.4e-25 88.9 0.6 3.2e-25 87.8 0.4 1.7 1 0 0 1 1 1 1 Helicase-associated putative binding domain, C-terminal Helicase_C PF00271.26 KKK21084.1 - 6.5e-16 57.9 0.3 1.8e-14 53.3 0.0 2.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.24 KKK21084.1 - 0.00047 19.7 0.0 0.0018 17.8 0.0 2.0 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 KKK21084.1 - 0.022 14.6 2.8 0.043 13.6 0.1 3.0 4 1 0 4 4 4 0 Type III restriction enzyme, res subunit HDA2-3 PF11496.3 KKK21084.1 - 0.025 13.3 0.0 0.06 12.1 0.0 1.6 1 0 0 1 1 1 0 Class II histone deacetylase complex subunits 2 and 3 AAA_34 PF13872.1 KKK21084.1 - 0.073 11.8 0.4 8.5 5.0 0.0 3.3 4 0 0 4 4 4 0 P-loop containing NTP hydrolase pore-1 Lipocalin_3 PF12702.2 KKK21084.1 - 0.16 12.0 1.5 0.59 10.1 0.1 2.6 3 0 0 3 3 3 0 Lipocalin-like GIT_SHD PF08518.6 KKK21085.1 - 4.4e-22 77.1 8.3 1.3e-13 50.0 0.7 2.8 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT PspB PF06667.7 KKK21085.1 - 0.0023 17.7 0.4 0.0023 17.7 0.3 2.6 3 0 0 3 3 3 1 Phage shock protein B APG6 PF04111.7 KKK21085.1 - 2.7 6.9 33.0 0.011 14.8 8.1 2.5 1 1 1 2 2 2 0 Autophagy protein Apg6 Pro_isomerase PF00160.16 KKK21086.1 - 1.3e-41 142.4 0.1 1.6e-41 142.0 0.1 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF3605 PF12239.3 KKK21087.1 - 2e-62 209.7 0.2 2.4e-62 209.4 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) Oxysterol_BP PF01237.13 KKK21088.1 - 6.4e-91 304.4 0.0 8.5e-91 304.0 0.0 1.1 1 0 0 1 1 1 1 Oxysterol-binding protein DUF1230 PF06799.6 KKK21088.1 - 0.078 12.8 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1230) Hist_deacetyl PF00850.14 KKK21089.1 - 8.6e-78 261.7 0.3 1.2e-77 261.3 0.2 1.1 1 0 0 1 1 1 1 Histone deacetylase domain Glyco_hydro_20 PF00728.17 KKK21092.1 - 1.4e-96 323.6 0.7 1.8e-96 323.3 0.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.1 KKK21092.1 - 6.6e-23 81.7 0.0 1.3e-22 80.7 0.0 1.5 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.10 KKK21092.1 - 5.1e-06 27.0 0.0 9.3e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Cutinase PF01083.17 KKK21093.1 - 5.3e-50 169.6 0.1 6.2e-50 169.4 0.0 1.0 1 0 0 1 1 1 1 Cutinase VirJ PF06057.6 KKK21093.1 - 0.00013 21.8 0.0 0.00015 21.6 0.0 1.2 1 0 0 1 1 1 1 Bacterial virulence protein (VirJ) PE-PPE PF08237.6 KKK21093.1 - 0.00037 20.0 0.0 0.0005 19.5 0.0 1.2 1 0 0 1 1 1 1 PE-PPE domain Creb_binding PF09030.5 KKK21093.1 - 0.012 15.8 0.0 0.1 12.7 0.0 2.1 2 0 0 2 2 2 0 Creb binding Abhydrolase_2 PF02230.11 KKK21093.1 - 0.044 13.2 0.0 0.07 12.5 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase SAS4 PF15460.1 KKK21094.1 - 1.4e-34 118.0 11.5 3e-34 116.9 8.0 1.6 1 0 0 1 1 1 1 Something about silencing, SAS, complex subunit 4 DHDPS PF00701.17 KKK21095.1 - 1e-47 162.1 0.0 1.1e-47 161.9 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family MFS_1 PF07690.11 KKK21096.1 - 1.4e-25 89.7 65.3 2.3e-17 62.7 22.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 KKK21096.1 - 0.0001 22.2 12.2 0.046 13.7 0.1 3.8 3 1 1 4 4 4 2 Protein of unknown function (DUF1228) MFS_2 PF13347.1 KKK21096.1 - 0.00019 19.9 16.5 0.00019 19.9 11.4 2.9 1 1 1 2 2 2 1 MFS/sugar transport protein Aa_trans PF01490.13 KKK21097.1 - 1.5e-43 148.8 35.1 1.8e-43 148.5 24.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Pal1 PF08316.6 KKK21098.1 - 4.6e-10 40.1 0.0 7.5e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 Pal1 cell morphology protein HVSL PF09749.4 KKK21099.1 - 1.8e-77 259.6 0.1 2.5e-77 259.1 0.1 1.2 1 0 0 1 1 1 1 Uncharacterised conserved protein DUF3807 PF12720.2 KKK21099.1 - 8.4e-42 143.2 0.1 1.4e-41 142.4 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3807) Alpha-L-AF_C PF06964.7 KKK21100.1 - 1.2e-31 109.8 2.0 2.4e-31 108.8 1.4 1.5 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminus Sugar_tr PF00083.19 KKK21101.1 - 3.6e-92 309.2 19.5 4.4e-92 309.0 13.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KKK21101.1 - 1.5e-26 92.9 25.4 1.4e-18 66.7 7.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 KKK21101.1 - 0.0042 16.8 7.0 1.5 8.6 0.0 4.4 4 0 0 4 4 4 2 MFS_1 like family DUF1228 PF06779.9 KKK21101.1 - 0.61 10.1 5.5 4 7.5 0.4 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1228) APH PF01636.18 KKK21111.1 - 8.9e-10 38.7 0.0 1.3e-09 38.1 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KKK21111.1 - 1.6e-05 24.6 0.0 2.4e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.15 KKK21111.1 - 0.14 11.2 0.0 0.27 10.3 0.0 1.4 1 1 0 1 1 1 0 Ecdysteroid kinase CitG PF01874.11 KKK21112.1 - 0.15 11.2 0.0 0.16 11.1 0.0 1.1 1 0 0 1 1 1 0 ATP:dephospho-CoA triphosphoribosyl transferase Arrestin_C PF02752.17 KKK21113.1 - 1.2e-22 80.4 0.0 1.1e-21 77.3 0.0 2.2 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 KKK21113.1 - 4.5e-08 33.0 0.2 0.0003 20.6 0.2 2.5 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.2 KKK21113.1 - 0.026 14.0 0.0 0.061 12.8 0.0 1.6 1 0 0 1 1 1 0 Arrestin_N terminal like MSA-2c PF12238.3 KKK21114.1 - 0.062 12.9 2.2 0.1 12.2 1.5 1.3 1 0 0 1 1 1 0 Merozoite surface antigen 2c RRM_1 PF00076.17 KKK21115.1 - 5.8e-19 67.4 0.0 7.6e-19 67.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KKK21115.1 - 6.5e-15 54.8 0.0 8.9e-15 54.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KKK21115.1 - 7.8e-10 38.4 0.0 1.2e-09 37.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KKK21115.1 - 0.0013 18.4 0.0 0.0018 18.0 0.0 1.2 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif KilA-N PF04383.8 KKK21118.1 - 0.00017 21.1 0.0 0.0031 17.1 0.0 2.2 1 1 0 1 1 1 1 KilA-N domain HA2 PF04408.18 KKK21119.1 - 1.9e-20 72.7 0.1 5.7e-20 71.2 0.1 1.9 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 KKK21119.1 - 1.2e-12 47.4 1.5 2e-12 46.8 0.1 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 KKK21119.1 - 4.9e-11 42.4 0.0 9.8e-11 41.4 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.11 KKK21119.1 - 1.3e-07 31.4 0.0 4.9e-07 29.5 0.0 2.0 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_22 PF13401.1 KKK21119.1 - 2.4e-06 27.7 0.0 8.3e-06 25.9 0.0 2.0 1 0 0 1 1 1 1 AAA domain DUF3554 PF12074.3 KKK21120.1 - 2.5e-100 336.2 14.7 1.1e-99 334.1 2.4 5.5 4 1 0 4 4 4 1 Domain of unknown function (DUF3554) Ribosomal_L19e PF01280.15 KKK21120.1 - 8.6e-58 194.3 9.9 2.2e-57 192.9 6.8 1.8 1 0 0 1 1 1 1 Ribosomal protein L19e HEAT_2 PF13646.1 KKK21120.1 - 1.1e-35 121.7 41.1 1.6e-08 34.6 0.9 14.8 6 3 8 14 14 14 9 HEAT repeats HEAT PF02985.17 KKK21120.1 - 1.2e-33 112.1 27.2 0.14 12.2 0.0 21.0 22 0 0 22 22 22 9 HEAT repeat HEAT_EZ PF13513.1 KKK21120.1 - 4.8e-24 84.1 53.3 0.013 15.9 0.1 21.6 18 5 8 26 26 26 9 HEAT-like repeat Cnd1 PF12717.2 KKK21120.1 - 1e-10 41.7 5.1 0.025 14.4 0.2 7.6 6 2 2 8 8 8 2 non-SMC mitotic condensation complex subunit 1 ParcG PF10274.4 KKK21120.1 - 1.1e-09 38.4 4.9 0.12 12.2 0.0 6.7 5 1 1 6 6 6 2 Parkin co-regulated protein Vac14_Fab1_bd PF12755.2 KKK21120.1 - 2.9e-09 37.1 0.0 2.2 8.7 0.0 8.4 7 2 3 10 10 10 1 Vacuolar 14 Fab1-binding region Ipi1_N PF12333.3 KKK21120.1 - 3.1e-07 30.3 0.5 0.99 9.4 0.0 6.1 5 0 0 5 5 5 2 Rix1 complex component involved in 60S ribosome maturation Cnd3 PF12719.2 KKK21120.1 - 0.0027 16.7 5.5 0.35 9.8 0.0 4.8 4 1 0 4 4 4 1 Nuclear condensing complex subunits, C-term domain SKG6 PF08693.5 KKK21121.1 - 0.14 11.5 0.5 0.27 10.5 0.3 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain TIP39 PF14980.1 KKK21122.1 - 0.42 10.2 0.1 0.42 10.2 0.0 2.4 3 0 0 3 3 3 0 TIP39 peptide Aminotran_1_2 PF00155.16 KKK21139.1 - 1.9e-62 211.3 0.0 2.6e-62 210.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 KKK21139.1 - 0.0015 17.7 0.0 0.0061 15.7 0.0 1.8 2 0 0 2 2 2 1 Beta-eliminating lyase Aminotran_5 PF00266.14 KKK21139.1 - 0.0085 14.8 0.0 0.013 14.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Cyclin PF08613.6 KKK21140.1 - 6.7e-17 62.2 0.0 1e-16 61.6 0.0 1.3 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 KKK21140.1 - 0.00013 21.5 0.0 0.00022 20.7 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Ribosomal_L18e PF00828.14 KKK21141.1 - 6.4e-14 52.4 1.1 1.6e-13 51.1 0.8 1.7 1 1 0 1 1 1 1 Ribosomal protein L18e/L15 GntR PF00392.16 KKK21141.1 - 0.12 11.7 0.1 0.56 9.6 0.0 2.0 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family Pkinase PF00069.20 KKK21142.1 - 4.3e-48 163.7 0.0 6.1e-48 163.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK21142.1 - 3.1e-28 98.5 0.0 6.8e-27 94.1 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KKK21142.1 - 0.038 13.7 0.2 0.36 10.5 0.0 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family NtA PF03146.10 KKK21142.1 - 0.092 12.3 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Agrin NtA domain Acetyltransf_10 PF13673.1 KKK21143.1 - 0.00017 21.7 0.1 0.0002 21.4 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain SH3_1 PF00018.23 KKK21144.1 - 2.9e-07 29.7 1.0 2.7e-06 26.6 0.0 2.4 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 KKK21144.1 - 0.0001 21.8 0.0 0.00021 20.7 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain PQ-loop PF04193.9 KKK21145.1 - 2e-35 120.1 12.4 7.2e-18 63.8 0.9 2.5 2 0 0 2 2 2 2 PQ loop repeat V_ATPase_I PF01496.14 KKK21145.1 - 0.25 9.1 0.1 0.35 8.6 0.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Proteasome PF00227.21 KKK21170.1 - 3.7e-27 94.8 0.0 4.4e-27 94.5 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit HSP20 PF00011.16 KKK21171.1 - 2.8e-16 59.2 1.1 8.9e-13 47.9 0.1 2.3 2 0 0 2 2 2 2 Hsp20/alpha crystallin family Autophagy_act_C PF03987.10 KKK21172.1 - 3.6e-13 49.4 0.1 6.7e-13 48.6 0.1 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain RRM_5 PF13893.1 KKK21173.1 - 8.3e-11 41.5 0.0 1.2e-10 41.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KKK21173.1 - 2.8e-09 36.4 0.0 6.4e-09 35.3 0.0 1.6 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KKK21173.1 - 6.4e-06 26.0 0.0 1.2e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 KKK21174.1 - 5.4e-22 76.8 10.0 3.7e-08 32.9 0.0 6.2 7 0 0 7 7 7 5 WD domain, G-beta repeat Rax2 PF12768.2 KKK21174.1 - 0.02 14.1 0.0 0.33 10.1 0.0 2.1 2 0 0 2 2 2 0 Cortical protein marker for cell polarity RhoGAP PF00620.22 KKK21175.1 - 1.8e-41 141.2 0.1 3.9e-41 140.2 0.1 1.5 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.24 KKK21175.1 - 4.2e-12 46.1 0.0 9.5e-12 45.0 0.0 1.6 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 KKK21175.1 - 3.3e-07 30.5 0.0 1.1e-06 28.8 0.0 1.9 2 0 0 2 2 2 1 Pleckstrin homology domain DUF3450 PF11932.3 KKK21175.1 - 0.008 15.4 0.4 0.014 14.6 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) PH_8 PF15409.1 KKK21175.1 - 0.029 14.4 0.0 0.21 11.6 0.0 2.3 2 0 0 2 2 2 0 Pleckstrin homology domain KH_1 PF00013.24 KKK21176.1 - 9.6e-06 25.1 1.7 2.2e-05 24.0 1.2 1.6 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 KKK21176.1 - 0.012 15.2 2.3 0.022 14.4 0.5 2.2 2 0 0 2 2 2 0 KH domain MDM31_MDM32 PF08118.6 KKK21177.1 - 2e-202 673.1 0.3 2.4e-202 672.9 0.2 1.0 1 0 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins Peptidase_M61 PF05299.7 KKK21177.1 - 0.13 12.2 0.0 0.98 9.4 0.0 2.2 2 0 0 2 2 2 0 M61 glycyl aminopeptidase HCNGP PF07818.8 KKK21178.1 - 5.9e-33 112.7 0.3 1.1e-32 111.9 0.2 1.4 1 0 0 1 1 1 1 HCNGP-like protein Proteasome PF00227.21 KKK21179.1 - 2.1e-33 115.2 0.1 7.5e-33 113.4 0.1 1.9 1 1 0 1 1 1 1 Proteasome subunit FAA_hydrolase PF01557.13 KKK21180.1 - 7.5e-61 205.3 0.0 9.4e-61 205.0 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family DUF2296 PF10058.4 KKK21186.1 - 2.1e-19 69.0 0.1 3.6e-19 68.2 0.1 1.4 1 0 0 1 1 1 1 Predicted integral membrane metal-binding protein (DUF2296) DUF2360 PF10152.4 KKK21186.1 - 1 9.6 16.5 0.2 11.9 2.3 2.5 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) Abhydrolase_3 PF07859.8 KKK21187.1 - 5.1e-43 147.0 0.0 6.5e-43 146.7 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 KKK21187.1 - 2e-10 40.0 2.8 8.2e-10 38.0 2.0 1.8 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 KKK21187.1 - 2.1e-05 24.2 0.0 2.6e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KKK21187.1 - 0.099 11.8 0.0 4.3 6.5 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family bZIP_1 PF00170.16 KKK21188.1 - 3.3e-09 36.5 10.0 1.3e-08 34.6 6.9 1.9 1 1 0 1 1 1 1 bZIP transcription factor Rab5-bind PF09311.6 KKK21188.1 - 0.005 16.7 1.5 0.011 15.6 1.0 1.5 1 0 0 1 1 1 1 Rabaptin-like protein IncA PF04156.9 KKK21188.1 - 0.045 13.3 0.8 0.066 12.8 0.6 1.3 1 0 0 1 1 1 0 IncA protein Adeno_PIX PF03955.9 KKK21188.1 - 0.053 14.0 1.0 0.053 14.0 0.7 1.8 2 0 0 2 2 2 0 Adenovirus hexon-associated protein (IX) DUF501 PF04417.7 KKK21188.1 - 0.074 12.8 0.3 0.12 12.1 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF501) bZIP_2 PF07716.10 KKK21188.1 - 1.4 8.8 18.1 21 5.0 9.8 2.6 2 1 0 2 2 2 0 Basic region leucine zipper Ribonuclease_3 PF00636.21 KKK21189.1 - 8.9e-32 109.9 0.0 9.1e-20 71.2 0.0 3.8 2 1 1 3 3 3 2 Ribonuclease III domain Dicer_dimer PF03368.9 KKK21189.1 - 1.1e-24 86.0 0.0 2.2e-24 85.0 0.0 1.5 1 0 0 1 1 1 1 Dicer dimerisation domain Ribonucleas_3_3 PF14622.1 KKK21189.1 - 3.1e-21 75.6 0.3 2.5e-10 40.3 0.0 4.5 3 1 0 3 3 3 2 Ribonuclease-III-like DEAD PF00270.24 KKK21189.1 - 7.3e-18 64.6 0.0 1.8e-17 63.3 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KKK21189.1 - 1e-14 54.1 0.0 3.1e-14 52.6 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KKK21189.1 - 2e-08 34.2 0.0 4.5e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit GMC_oxred_N PF00732.14 KKK21190.1 - 7.2e-52 176.3 0.0 9.7e-52 175.9 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KKK21190.1 - 2.5e-31 108.9 0.1 4.2e-31 108.1 0.1 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.7 KKK21190.1 - 1.6e-05 24.0 0.0 2.5e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.19 KKK21190.1 - 0.00011 21.2 0.0 0.0033 16.3 0.0 2.5 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KKK21190.1 - 0.00016 21.6 0.1 0.00037 20.4 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 KKK21190.1 - 0.0083 15.0 0.0 0.66 8.7 0.0 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_2 PF00890.19 KKK21190.1 - 0.0094 14.8 0.0 0.016 14.0 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 KKK21190.1 - 0.01 15.7 0.0 0.022 14.6 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KKK21190.1 - 0.042 12.3 0.0 0.12 10.8 0.0 1.6 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox_3 PF13738.1 KKK21190.1 - 0.072 13.1 0.0 0.21 11.6 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 KKK21190.1 - 0.1 12.0 0.0 0.22 10.9 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_9 PF13454.1 KKK21190.1 - 0.13 12.0 0.0 0.29 10.9 0.0 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding Endonuclease_1 PF04231.8 KKK21191.1 - 5.6e-05 23.0 0.1 6.9e-05 22.7 0.1 1.1 1 0 0 1 1 1 1 Endonuclease I SR-25 PF10500.4 KKK21191.1 - 0.0053 16.2 13.3 0.0068 15.9 9.2 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Acetyltransf_4 PF13420.1 KKK21193.1 - 1.2e-05 25.2 0.0 2.7e-05 24.1 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KKK21193.1 - 8.3e-05 22.5 0.0 0.00016 21.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KKK21193.1 - 0.002 18.2 0.0 0.0034 17.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 KKK21193.1 - 0.0047 17.0 0.0 0.0059 16.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KKK21193.1 - 0.01 15.9 0.0 0.021 14.9 0.0 1.6 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KKK21193.1 - 0.025 14.4 0.0 0.21 11.4 0.0 2.3 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Anoctamin PF04547.7 KKK21194.1 - 1.4e-125 419.5 3.2 1.8e-125 419.1 2.2 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel GST_N_2 PF13409.1 KKK21194.1 - 3.3e-17 62.2 0.0 8.5e-17 60.9 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KKK21194.1 - 1.7e-10 40.6 0.0 5.2e-10 39.0 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KKK21194.1 - 1.6e-05 25.2 0.0 4.6e-05 23.8 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain ABC_membrane PF00664.18 KKK21194.1 - 0.0053 16.1 0.1 0.0053 16.1 0.0 2.6 3 0 0 3 3 3 1 ABC transporter transmembrane region GST_N_3 PF13417.1 KKK21194.1 - 0.031 14.4 0.0 2.2 8.5 0.0 2.6 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain GRIP PF01465.15 KKK21195.1 - 1.5e-15 56.3 0.2 3.6e-15 55.1 0.1 1.6 1 0 0 1 1 1 1 GRIP domain Acetyltransf_1 PF00583.19 KKK21195.1 - 7.7e-13 48.2 0.0 1.8e-12 47.1 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Reo_sigmaC PF04582.7 KKK21195.1 - 1.5e-07 30.9 42.9 0.023 13.8 2.5 6.6 3 2 3 6 6 6 5 Reovirus sigma C capsid protein FR47 PF08445.5 KKK21195.1 - 1.1e-06 28.2 0.0 2.4e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 KKK21195.1 - 1.8e-05 24.7 0.0 4.1e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF869 PF05911.6 KKK21195.1 - 0.00018 19.9 125.5 0.003 15.8 9.0 4.7 1 1 3 4 4 4 3 Plant protein of unknown function (DUF869) Acetyltransf_3 PF13302.1 KKK21195.1 - 0.00031 20.9 0.0 0.0011 19.0 0.0 2.0 2 0 0 2 2 1 1 Acetyltransferase (GNAT) domain DUF3584 PF12128.3 KKK21195.1 - 0.00044 17.7 45.0 0.00044 17.7 31.2 4.3 2 2 1 3 3 3 2 Protein of unknown function (DUF3584) Filament PF00038.16 KKK21195.1 - 0.00095 18.7 44.1 0.00095 18.7 30.6 7.6 1 1 5 6 6 6 3 Intermediate filament protein CCDC155 PF14662.1 KKK21195.1 - 0.0011 18.5 16.1 0.0011 18.5 11.1 6.9 2 2 4 6 6 3 1 Coiled-coil region of CCDC155 CENP-F_leu_zip PF10473.4 KKK21195.1 - 0.002 18.0 36.5 0.0029 17.4 15.1 10.1 2 2 6 9 9 9 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GAS PF13851.1 KKK21195.1 - 0.0029 16.8 150.5 0.028 13.6 9.6 10.3 2 2 8 10 10 10 7 Growth-arrest specific micro-tubule binding IncA PF04156.9 KKK21195.1 - 0.0032 17.0 163.1 0.083 12.4 8.4 9.1 2 2 7 9 9 9 2 IncA protein FliJ PF02050.11 KKK21195.1 - 0.0058 16.6 17.7 0.0058 16.6 12.3 9.6 3 3 5 9 9 8 2 Flagellar FliJ protein Acetyltransf_10 PF13673.1 KKK21195.1 - 0.0072 16.4 0.0 0.025 14.6 0.0 1.9 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Myosin_tail_1 PF01576.14 KKK21195.1 - 0.0075 14.0 168.3 0.097 10.3 15.3 4.3 2 2 2 4 4 4 4 Myosin tail Spc7 PF08317.6 KKK21195.1 - 0.013 14.2 132.7 0.069 11.8 13.7 7.3 3 2 4 7 7 7 0 Spc7 kinetochore protein AAA_13 PF13166.1 KKK21195.1 - 1 7.7 114.3 1.1 7.6 18.9 5.3 2 2 3 5 5 5 0 AAA domain Fib_alpha PF08702.5 KKK21195.1 - 2 8.5 87.3 0.16 12.1 2.8 7.9 3 2 4 8 8 8 0 Fibrinogen alpha/beta chain family Ank_2 PF12796.2 KKK21196.1 - 3.9e-28 97.6 0.0 1.1e-13 51.2 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KKK21196.1 - 9.3e-26 89.7 0.5 3.7e-11 43.2 0.0 3.7 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.25 KKK21196.1 - 5.4e-24 82.7 3.5 1.7e-06 27.4 0.1 5.3 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.1 KKK21196.1 - 4.9e-21 74.2 2.5 1.4e-08 34.6 0.0 4.4 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 KKK21196.1 - 9e-17 59.5 0.5 1.3e-05 25.0 0.0 4.6 5 0 0 5 5 5 4 Ankyrin repeat cNMP_binding PF00027.24 KKK21197.1 - 6.6e-39 131.6 0.2 2.4e-21 75.3 0.0 4.7 4 1 0 4 4 4 3 Cyclic nucleotide-binding domain Patatin PF01734.17 KKK21197.1 - 2.7e-19 69.9 5.9 3.8e-18 66.1 4.1 2.6 1 1 0 1 1 1 1 Patatin-like phospholipase SGT1 PF07093.6 KKK21197.1 - 0.25 9.6 0.0 0.41 8.9 0.0 1.2 1 0 0 1 1 1 0 SGT1 protein Copper-fist PF00649.13 KKK21198.1 - 1.7e-19 68.7 0.3 5.8e-19 67.0 0.2 2.0 1 0 0 1 1 1 1 Copper fist DNA binding domain RVT_1 PF00078.22 KKK21199.1 - 3.7e-08 32.9 0.0 7.7e-08 31.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Transp_cyt_pur PF02133.10 KKK21200.1 - 1.8e-150 501.3 32.4 2e-150 501.1 22.5 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Urb2 PF10441.4 KKK21201.1 - 9.5e-70 234.6 0.0 9.5e-70 234.6 0.0 2.8 4 0 0 4 4 4 1 Urb2/Npa2 family DUF543 PF04418.7 KKK21202.1 - 6.5e-26 90.0 0.0 7e-26 89.9 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF543) CPSF100_C PF13299.1 KKK21205.1 - 4.1e-46 157.1 0.3 8e-46 156.1 0.0 1.7 2 0 0 2 2 2 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.3 KKK21205.1 - 8.5e-27 93.5 0.0 1.5e-25 89.6 0.0 2.7 3 0 0 3 3 3 1 Beta-Casp domain RMMBL PF07521.7 KKK21205.1 - 0.00052 19.7 0.0 0.0012 18.5 0.0 1.6 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B PF00753.22 KKK21205.1 - 0.0062 16.1 0.6 0.037 13.6 0.4 2.4 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily PGM_PMM_IV PF00408.15 KKK21205.1 - 0.008 16.1 0.0 0.025 14.5 0.0 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain AA_permease_2 PF13520.1 KKK21206.1 - 9e-45 152.9 35.0 1.1e-44 152.7 24.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KKK21206.1 - 4.5e-14 51.6 27.9 6.1e-14 51.2 19.3 1.1 1 0 0 1 1 1 1 Amino acid permease Frag1 PF10277.4 KKK21207.1 - 2.6e-41 141.4 9.9 2.6e-41 141.4 6.9 2.8 3 0 0 3 3 3 1 Frag1/DRAM/Sfk1 family Exo_endo_phos PF03372.18 KKK21207.1 - 0.00013 21.9 0.0 0.00032 20.7 0.0 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF443 PF04276.7 KKK21207.1 - 0.14 11.5 2.6 0.29 10.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF443) Glyco_hydro_32N PF00251.15 KKK21208.1 - 5.2e-95 318.3 3.7 6.8e-95 317.9 2.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.7 KKK21208.1 - 2.5e-19 69.4 2.2 3e-19 69.1 0.1 2.3 3 0 0 3 3 3 1 Glycosyl hydrolases family 32 C terminal BNR PF02012.15 KKK21208.1 - 0.0071 15.9 1.0 0.044 13.5 0.7 2.5 1 0 0 1 1 1 1 BNR/Asp-box repeat RF-1 PF00472.15 KKK21209.1 - 1.7e-14 53.5 0.5 2.5e-14 53.0 0.3 1.2 1 0 0 1 1 1 1 RF-1 domain DUF4391 PF14335.1 KKK21209.1 - 0.066 12.5 0.9 0.092 12.1 0.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4391) U3_assoc_6 PF08640.6 KKK21210.1 - 2.3e-30 104.1 0.7 4.1e-30 103.3 0.5 1.4 1 0 0 1 1 1 1 U3 small nucleolar RNA-associated protein 6 TPR_14 PF13428.1 KKK21210.1 - 0.0042 17.5 0.1 0.15 12.7 0.1 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat Suf PF05843.9 KKK21210.1 - 1.3 8.6 5.6 15 5.2 0.2 2.8 3 0 0 3 3 3 0 Suppressor of forked protein (Suf) RRM_1 PF00076.17 KKK21212.1 - 8.3e-10 38.1 0.0 1.5e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KKK21212.1 - 8.4e-08 32.0 0.0 1.6e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KKK21212.1 - 0.072 12.9 0.2 0.13 12.1 0.1 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SYS1 PF09801.4 KKK21213.1 - 1.1e-47 161.7 11.6 2.3e-47 160.6 8.0 1.5 1 1 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network DUF485 PF04341.7 KKK21213.1 - 6.6 6.5 12.9 0.99 9.1 5.5 2.1 1 1 2 3 3 3 0 Protein of unknown function, DUF485 COX6B PF02297.12 KKK21214.1 - 4.2e-23 81.1 5.1 6.8e-23 80.4 3.5 1.3 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb Prolamin_like PF05617.6 KKK21214.1 - 0.066 13.3 0.9 0.16 12.1 0.6 1.7 1 1 0 1 1 1 0 Prolamin-like Bromo_MP PF01573.11 KKK21214.1 - 0.16 10.9 2.3 1.3 7.9 0.1 2.0 2 0 0 2 2 2 0 Bromovirus movement protein DUF3304 PF11745.3 KKK21215.1 - 0.59 10.3 5.3 0.13 12.4 0.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3304) Sec23_trunk PF04811.10 KKK21216.1 - 5.6e-57 192.8 0.0 9e-57 192.2 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 KKK21216.1 - 3.4e-25 87.4 0.0 6.2e-25 86.6 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 KKK21216.1 - 3e-18 66.1 0.0 5.5e-18 65.2 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 KKK21216.1 - 5.1e-17 61.1 6.5 9.5e-17 60.2 4.5 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 KKK21216.1 - 3.7e-07 29.7 0.0 7.3e-07 28.7 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat SLS PF14611.1 KKK21216.1 - 0.00035 20.0 0.0 0.0006 19.2 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial inner-membrane-bound regulator Fungal_trans_2 PF11951.3 KKK21217.1 - 1e-63 215.2 0.0 1.2e-63 215.0 0.0 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain YcbB PF08664.5 KKK21217.1 - 0.1 12.3 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 YcbB domain Aldolase_II PF00596.16 KKK21218.1 - 6.5e-41 139.9 0.1 1.2e-40 139.0 0.1 1.5 1 1 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain COG5 PF10392.4 KKK21219.1 - 6.7e-41 139.3 3.7 1.9e-40 137.9 0.2 2.7 3 0 0 3 3 3 1 Golgi transport complex subunit 5 CENP-F_leu_zip PF10473.4 KKK21219.1 - 0.26 11.1 1.5 0.48 10.2 0.3 1.9 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PhyH PF05721.8 KKK21255.1 - 1.1e-07 32.0 0.0 3.6e-06 27.1 0.0 2.5 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Het-C PF07217.6 KKK21256.1 - 2.2e-295 980.6 0.0 2.2e-295 980.6 0.0 1.4 2 0 0 2 2 2 1 Heterokaryon incompatibility protein Het-C TctA PF01970.11 KKK21256.1 - 0.015 13.7 0.0 0.024 13.0 0.0 1.2 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctA family IBN_N PF03810.14 KKK21257.1 - 1.2e-11 44.3 0.1 4.9e-08 32.7 0.0 4.2 2 1 1 3 3 3 1 Importin-beta N-terminal domain Xpo1 PF08389.7 KKK21257.1 - 1.8e-05 24.6 0.8 0.046 13.6 0.0 4.4 5 0 0 5 5 5 2 Exportin 1-like protein Cnd3 PF12719.2 KKK21257.1 - 0.0014 17.7 1.5 0.23 10.4 0.3 3.4 2 1 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain CAS_CSE1 PF03378.10 KKK21257.1 - 0.0064 14.8 0.0 0.015 13.6 0.0 1.6 1 0 0 1 1 1 1 CAS/CSE protein, C-terminus DUF1678 PF07913.6 KKK21257.1 - 0.066 12.7 0.0 0.17 11.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1678) DUF937 PF06078.6 KKK21257.1 - 0.18 12.0 3.6 39 4.4 0.0 4.0 4 1 0 5 5 5 0 Bacterial protein of unknown function (DUF937) Methyltransf_23 PF13489.1 KKK21258.1 - 8.1e-23 80.9 0.0 1.3e-22 80.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KKK21258.1 - 6e-11 42.9 0.0 3.1e-10 40.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KKK21258.1 - 2.1e-10 40.9 0.0 5.6e-10 39.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KKK21258.1 - 5.2e-10 39.1 0.0 2.5e-09 36.9 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KKK21258.1 - 2.6e-08 34.2 0.0 5.8e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KKK21258.1 - 0.00038 20.4 0.0 0.0016 18.4 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 KKK21258.1 - 0.002 17.2 0.0 0.0066 15.5 0.0 1.7 2 0 0 2 2 2 1 Putative methyltransferase CMAS PF02353.15 KKK21258.1 - 0.002 17.2 0.0 0.0053 15.8 0.0 1.7 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_16 PF10294.4 KKK21258.1 - 0.0028 17.1 0.0 0.0047 16.3 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.9 KKK21258.1 - 0.0049 16.2 0.0 0.041 13.2 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase small domain FtsJ PF01728.14 KKK21258.1 - 0.0063 16.5 0.0 0.0097 15.9 0.0 1.3 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_25 PF13649.1 KKK21258.1 - 0.015 15.6 0.0 0.061 13.6 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain PrmA PF06325.8 KKK21258.1 - 0.019 14.0 0.0 0.027 13.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DUF938 PF06080.7 KKK21258.1 - 0.089 12.3 0.0 0.36 10.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF938) IBR PF01485.16 KKK21259.1 - 1.2e-06 28.2 7.4 1.2e-06 28.2 5.1 3.6 3 1 0 3 3 3 2 IBR domain Peptidase_U57 PF05582.7 KKK21259.1 - 0.91 8.4 3.4 0.65 8.9 0.3 2.1 3 0 0 3 3 3 0 YabG peptidase U57 HORMA PF02301.13 KKK21260.1 - 8.4e-26 90.7 0.0 1.1e-25 90.3 0.0 1.1 1 0 0 1 1 1 1 HORMA domain DUF2036 PF09724.4 KKK21261.1 - 5.4e-15 55.3 0.0 2.9e-14 52.9 0.0 2.0 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2036) Nucleoplasmin PF03066.10 KKK21261.1 - 0.00052 19.5 1.9 0.00087 18.8 1.3 1.3 1 0 0 1 1 1 1 Nucleoplasmin DUF4611 PF15387.1 KKK21261.1 - 0.0049 16.9 4.3 0.012 15.7 3.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4611) NOA36 PF06524.7 KKK21261.1 - 0.11 11.7 7.2 0.18 11.0 5.0 1.3 1 0 0 1 1 1 0 NOA36 protein SH3_4 PF06347.8 KKK21261.1 - 0.21 11.1 1.0 0.61 9.6 0.1 2.3 2 1 0 2 2 2 0 Bacterial SH3 domain RXT2_N PF08595.6 KKK21261.1 - 0.29 10.9 5.0 0.53 10.0 3.4 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal Sigma70_ner PF04546.8 KKK21261.1 - 0.37 10.3 5.4 0.73 9.4 3.8 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region CENP-B_dimeris PF09026.5 KKK21261.1 - 0.95 9.7 10.8 2.1 8.6 7.5 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Bd3614_N PF14442.1 KKK21261.1 - 1 9.3 5.6 2.2 8.2 3.9 1.5 1 0 0 1 1 1 0 Bd3614-like deaminase N-terminal PBP1_TM PF14812.1 KKK21261.1 - 2 8.7 9.3 5.4 7.4 6.4 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Cwf_Cwc_15 PF04889.7 KKK21261.1 - 2.8 7.5 15.0 0.06 13.0 5.3 1.8 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Acetyltransf_7 PF13508.1 KKK21262.1 - 1.7e-06 28.1 0.0 3.2e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KKK21262.1 - 0.00012 21.9 0.0 0.00045 20.0 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KKK21262.1 - 0.00027 20.8 0.2 0.00094 19.1 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family FR47 PF08445.5 KKK21262.1 - 0.0027 17.4 0.1 0.014 15.1 0.0 2.2 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_3 PF13302.1 KKK21262.1 - 0.0033 17.5 0.0 0.0073 16.4 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KKK21262.1 - 0.0045 17.1 0.0 0.012 15.7 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain zf-TRAF PF02176.13 KKK21263.1 - 4.1e-12 46.2 32.7 4e-10 39.9 3.0 4.4 1 1 3 4 4 4 3 TRAF-type zinc finger zf-RING_2 PF13639.1 KKK21263.1 - 1.8e-07 30.8 13.0 1.8e-07 30.8 9.0 3.5 2 1 1 3 3 1 1 Ring finger domain zf-C3HC4 PF00097.20 KKK21263.1 - 3.2e-07 29.8 11.9 3.2e-07 29.8 8.2 3.3 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KKK21263.1 - 3.3e-06 26.7 11.5 3.3e-06 26.7 8.0 3.8 4 1 0 4 4 3 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 KKK21263.1 - 6.7e-06 25.8 12.3 6.7e-06 25.8 8.6 2.9 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 KKK21263.1 - 1.5e-05 24.5 10.5 1.5e-05 24.5 7.2 3.2 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KKK21263.1 - 1.7e-05 24.4 8.2 1.7e-05 24.4 5.7 3.0 3 0 0 3 3 3 1 RING-type zinc-finger Sina PF03145.11 KKK21263.1 - 2.1e-05 24.3 17.6 0.0029 17.3 4.2 3.3 1 1 2 3 3 3 2 Seven in absentia protein family zf-C3HC4_2 PF13923.1 KKK21263.1 - 3.7e-05 23.6 13.3 3.7e-05 23.6 9.2 3.4 2 1 1 3 3 2 1 Zinc finger, C3HC4 type (RING finger) Prominin PF05478.6 KKK21263.1 - 0.022 12.2 1.8 0.031 11.8 1.2 1.1 1 0 0 1 1 1 0 Prominin PilN PF05137.8 KKK21263.1 - 0.034 13.9 0.1 0.074 12.8 0.0 1.6 1 0 0 1 1 1 0 Fimbrial assembly protein (PilN) SNARE PF05739.14 KKK21264.1 - 3e-14 52.4 3.2 3e-14 52.4 2.2 2.2 2 0 0 2 2 2 1 SNARE domain MDMPI_N PF11716.3 KKK21264.1 - 0.012 16.0 0.1 0.034 14.5 0.1 1.7 1 0 0 1 1 1 0 Mycothiol maleylpyruvate isomerase N-terminal domain Phage_GP20 PF06810.6 KKK21264.1 - 0.023 14.1 2.3 2.1 7.7 0.1 2.7 3 0 0 3 3 3 0 Phage minor structural protein GP20 TPR_19 PF14559.1 KKK21264.1 - 0.05 13.9 0.0 0.13 12.5 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat FliJ PF02050.11 KKK21264.1 - 0.064 13.3 3.6 0.74 9.8 0.3 2.9 2 1 1 3 3 3 0 Flagellar FliJ protein TPR_MLP1_2 PF07926.7 KKK21264.1 - 0.097 12.4 0.3 0.097 12.4 0.2 1.9 3 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein Use1 PF09753.4 KKK21264.1 - 0.1 12.0 0.0 0.17 11.3 0.0 1.5 1 1 0 1 1 1 0 Membrane fusion protein Use1 Syntaxin PF00804.20 KKK21264.1 - 0.23 11.6 0.2 0.23 11.6 0.2 2.4 2 1 0 2 2 2 0 Syntaxin WXG100 PF06013.7 KKK21264.1 - 0.28 11.1 2.3 5.2 7.1 0.1 3.2 2 2 1 3 3 3 0 Proteins of 100 residues with WXG Tropomyosin PF00261.15 KKK21264.1 - 1.9 7.5 7.2 16 4.4 0.0 3.3 3 1 1 4 4 4 0 Tropomyosin PilJ PF13675.1 KKK21264.1 - 4.2 7.7 7.1 0.71 10.2 0.1 2.5 3 0 0 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term Anp1 PF03452.9 KKK21265.1 - 4.5e-122 406.3 0.0 6.9e-122 405.7 0.0 1.3 1 0 0 1 1 1 1 Anp1 adh_short PF00106.20 KKK21265.1 - 1.5e-11 44.5 0.0 2.9e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KKK21265.1 - 2.4e-06 27.3 0.0 4.1e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KKK21265.1 - 0.001 18.5 0.0 0.0016 17.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 KKK21265.1 - 0.12 11.2 0.0 0.22 10.3 0.0 1.4 1 0 0 1 1 1 0 Male sterility protein FAD_binding_4 PF01565.18 KKK21266.1 - 4.9e-18 64.9 0.8 1.3e-17 63.5 0.5 1.8 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KKK21266.1 - 6e-08 32.4 0.2 1.2e-07 31.4 0.1 1.6 1 0 0 1 1 1 1 Berberine and berberine like DUF4266 PF14086.1 KKK21267.1 - 2 8.9 5.9 0.31 11.5 1.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4266) Asp PF00026.18 KKK21268.1 - 3.4e-64 217.1 9.6 4e-64 216.8 6.7 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KKK21268.1 - 9e-05 22.4 0.1 0.0003 20.7 0.1 1.9 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 KKK21268.1 - 0.0003 21.2 1.7 0.57 10.7 0.2 2.7 2 1 0 2 2 2 2 Aspartyl protease ParA PF10609.4 KKK21269.1 - 1.1e-35 121.3 0.0 2.4e-35 120.2 0.0 1.6 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 KKK21269.1 - 2.9e-15 56.2 0.0 4.3e-15 55.6 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 KKK21269.1 - 5e-06 26.5 0.0 2.1e-05 24.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.10 KKK21269.1 - 1.5e-05 24.1 1.9 0.00051 19.1 0.2 2.7 2 1 0 2 2 2 1 Anion-transporting ATPase MipZ PF09140.6 KKK21269.1 - 0.0055 15.8 0.0 0.014 14.5 0.0 1.6 1 1 0 1 1 1 1 ATPase MipZ AAA_26 PF13500.1 KKK21269.1 - 0.0057 16.2 0.0 0.39 10.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 KKK21269.1 - 0.0092 15.1 0.0 0.017 14.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Zn_Tnp_IS1595 PF12760.2 KKK21269.1 - 0.088 12.6 0.1 0.28 11.0 0.0 1.8 1 0 0 1 1 1 0 Transposase zinc-ribbon domain AAA_25 PF13481.1 KKK21269.1 - 0.1 11.9 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 KKK21269.1 - 0.12 11.9 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain ChW PF07538.6 KKK21269.1 - 7.4 6.1 6.2 0.73 9.4 0.7 2.1 2 0 0 2 2 2 0 Clostridial hydrophobic W PEMT PF04191.8 KKK21270.1 - 9.1e-54 180.0 17.4 8.6e-35 119.0 1.0 3.0 3 0 0 3 3 3 2 Phospholipid methyltransferase RNase_PH PF01138.16 KKK21271.1 - 3.3e-32 111.5 0.0 7e-32 110.5 0.0 1.6 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 PRT_C PF08372.5 KKK21271.1 - 0.11 11.9 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 Plant phosphoribosyltransferase C-terminal HTH_AsnC-type PF13404.1 KKK21272.1 - 0.068 12.7 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain Cyclin_N PF00134.18 KKK21273.1 - 3.3e-11 42.8 0.0 6.4e-11 41.9 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain DUF4452 PF14618.1 KKK21274.1 - 9e-74 246.7 6.7 1.1e-73 246.4 4.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4452) GST_N_2 PF13409.1 KKK21275.1 - 5.6e-21 74.3 0.0 1.3e-20 73.1 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KKK21275.1 - 1.2e-17 63.5 0.0 2.1e-17 62.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 KKK21275.1 - 4.8e-07 29.9 0.1 2.4e-05 24.4 0.1 2.4 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 KKK21275.1 - 1.1e-05 25.7 0.0 2.3e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KKK21275.1 - 1.7e-05 24.7 0.0 3.4e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Mito_carr PF00153.22 KKK21276.1 - 1.8e-67 223.1 3.4 3.6e-22 77.8 0.1 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.1 KKK21276.1 - 3.7e-22 78.2 2.2 3.5e-13 49.4 0.1 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 KKK21276.1 - 2e-20 70.4 5.4 1.8e-06 26.8 0.1 3.8 4 0 0 4 4 4 3 EF hand EF-hand_5 PF13202.1 KKK21276.1 - 3.3e-18 64.1 3.6 5e-06 25.6 0.1 3.7 3 1 0 3 3 3 3 EF hand EF-hand_6 PF13405.1 KKK21276.1 - 7.2e-14 50.3 6.7 0.00077 19.1 0.0 4.0 3 1 1 4 4 4 3 EF-hand domain EF-hand_8 PF13833.1 KKK21276.1 - 2.1e-12 46.4 0.7 7.8e-07 28.6 0.0 2.7 1 1 0 2 2 2 2 EF-hand domain pair SPARC_Ca_bdg PF10591.4 KKK21276.1 - 3.5e-07 30.2 0.1 0.0022 18.0 0.0 2.3 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.1 KKK21276.1 - 0.0096 15.5 0.9 7.1 6.3 0.0 3.4 4 0 0 4 4 4 2 EF hand Spc97_Spc98 PF04130.8 KKK21277.1 - 3.3e-87 293.0 0.0 4.2e-87 292.6 0.0 1.1 1 0 0 1 1 1 1 Spc97 / Spc98 family Myosin_tail_1 PF01576.14 KKK21277.1 - 0.11 10.1 0.2 0.17 9.6 0.1 1.1 1 0 0 1 1 1 0 Myosin tail ThiF PF00899.16 KKK21278.1 - 2.8e-53 179.3 0.0 7.2e-31 106.8 0.0 2.5 2 0 0 2 2 2 2 ThiF family UBACT PF02134.16 KKK21278.1 - 1.5e-40 136.5 0.8 2.5e-26 91.0 0.2 2.5 2 0 0 2 2 2 2 Repeat in ubiquitin-activating (UBA) protein UBA_e1_C PF09358.5 KKK21278.1 - 8.6e-39 132.5 0.0 2.3e-38 131.2 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-activating enzyme e1 C-terminal domain UBA_e1_thiolCys PF10585.4 KKK21278.1 - 1.8e-24 84.8 2.3 1.8e-21 75.2 0.3 2.5 2 0 0 2 2 2 2 Ubiquitin-activating enzyme active site Pkinase PF00069.20 KKK21278.1 - 1.7e-16 60.1 0.0 3.1e-16 59.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK21278.1 - 1.5e-11 43.9 0.0 3.5e-11 42.6 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase MFS_1 PF07690.11 KKK21279.1 - 5.3e-31 107.6 25.9 5.3e-31 107.6 18.0 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 KKK21279.1 - 0.0024 17.6 4.3 0.42 10.4 0.5 2.8 2 0 0 2 2 2 2 MFS_1 like family adh_short PF00106.20 KKK21280.1 - 7.6e-29 100.7 5.6 1e-28 100.3 3.9 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KKK21280.1 - 5.2e-27 95.1 0.5 6.4e-27 94.8 0.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KKK21280.1 - 7.8e-14 51.7 2.7 1.2e-13 51.1 1.8 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KKK21280.1 - 5.2e-05 22.7 1.0 0.00012 21.6 0.7 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Hexokinase_2 PF03727.11 KKK21281.1 - 4.6e-27 94.7 0.0 2.7e-21 75.8 0.0 2.2 2 0 0 2 2 2 2 Hexokinase Hexokinase_1 PF00349.16 KKK21281.1 - 4e-26 91.6 0.0 8e-25 87.3 0.0 2.6 1 1 0 1 1 1 1 Hexokinase GILT PF03227.11 KKK21282.1 - 7.4e-10 38.6 0.1 1.2e-09 37.9 0.1 1.4 1 0 0 1 1 1 1 Gamma interferon inducible lysosomal thiol reductase (GILT) ALMS_motif PF15309.1 KKK21283.1 - 0.86 9.4 6.2 0.3 10.9 1.8 2.0 2 0 0 2 2 2 0 ALMS motif TFIIA_gamma_C PF02751.9 KKK21284.1 - 5.4e-27 93.3 2.7 7.7e-27 92.8 1.9 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit TFIIA_gamma_N PF02268.11 KKK21284.1 - 3.3e-26 90.6 0.2 4.6e-26 90.1 0.2 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain TFIIA PF03153.8 KKK21311.1 - 3.5 7.4 9.7 8.2 6.2 6.8 1.7 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Glyco_hydro_17 PF00332.13 KKK21312.1 - 1.1e-09 37.7 3.7 8.4e-06 25.0 0.7 2.2 1 1 1 2 2 2 2 Glycosyl hydrolases family 17 PHD PF00628.24 KKK21314.1 - 1e-09 37.9 2.7 2.4e-09 36.7 1.9 1.6 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 KKK21314.1 - 0.0095 15.2 3.4 0.015 14.5 2.4 1.4 1 0 0 1 1 1 1 PHD-finger eIF-5a PF01287.15 KKK21315.1 - 0.0011 18.9 0.0 0.0021 17.9 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold SRR1 PF07985.7 KKK21317.1 - 6.5e-15 54.8 0.0 1.1e-14 54.0 0.0 1.4 1 0 0 1 1 1 1 SRR1 RRP7 PF12923.2 KKK21317.1 - 0.11 12.5 1.0 0.19 11.7 0.2 1.7 2 0 0 2 2 2 0 Ribosomal RNA-processing protein 7 (RRP7) TrkH PF02386.11 KKK21325.1 - 2.3e-76 256.6 5.4 2.3e-76 256.6 3.7 1.6 2 0 0 2 2 2 1 Cation transport protein MoaC PF01967.16 KKK21326.1 - 1e-46 157.9 0.1 1.7e-46 157.2 0.1 1.3 1 0 0 1 1 1 1 MoaC family Mob_synth_C PF06463.8 KKK21326.1 - 3.4e-36 123.7 0.0 2.5e-35 120.9 0.0 2.2 2 0 0 2 2 2 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.16 KKK21326.1 - 9.8e-21 74.6 0.0 1.8e-20 73.7 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.1 KKK21326.1 - 3.6e-05 23.7 0.0 0.00045 20.2 0.0 2.3 2 0 0 2 2 2 1 4Fe-4S single cluster domain Fer4_12 PF13353.1 KKK21326.1 - 7.2e-05 22.9 0.0 0.00018 21.6 0.0 1.6 1 0 0 1 1 1 1 4Fe-4S single cluster domain Pyr_redox_dim PF02852.17 KKK21327.1 - 1.6e-34 118.2 0.1 1.9e-34 118.0 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Glyco_hydro_16 PF00722.16 KKK21328.1 - 2e-43 147.8 1.9 2e-43 147.8 1.3 2.3 2 1 0 2 2 2 1 Glycosyl hydrolases family 16 Hira PF07569.6 KKK21328.1 - 0.15 11.2 3.9 0.24 10.5 2.7 1.3 1 0 0 1 1 1 0 TUP1-like enhancer of split Phage_GPO PF05929.6 KKK21329.1 - 0.019 14.2 1.4 0.029 13.6 0.5 1.7 1 1 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Cast PF10174.4 KKK21329.1 - 0.036 12.1 0.2 0.036 12.1 0.1 1.4 2 0 0 2 2 2 0 RIM-binding protein of the cytomatrix active zone Baculo_PEP_C PF04513.7 KKK21329.1 - 0.039 13.7 0.4 8.5 6.1 0.0 2.4 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Methyltransf_15 PF09445.5 KKK21329.1 - 0.11 12.0 0.1 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase DASH_Dad2 PF08654.5 KKK21329.1 - 0.15 12.0 0.5 0.47 10.4 0.0 2.0 2 0 0 2 2 2 0 DASH complex subunit Dad2 Fez1 PF06818.10 KKK21329.1 - 0.15 12.0 1.2 0.3 11.0 0.9 1.4 1 0 0 1 1 1 0 Fez1 Syntaxin-6_N PF09177.6 KKK21329.1 - 0.39 11.1 2.9 2.3 8.6 0.2 2.7 3 0 0 3 3 3 0 Syntaxin 6, N-terminal NPV_P10 PF05531.7 KKK21329.1 - 0.46 10.7 3.4 3 8.1 0.4 3.2 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Adeno_PIX PF03955.9 KKK21329.1 - 1 9.9 4.9 0.86 10.1 0.2 2.9 4 0 0 4 4 4 0 Adenovirus hexon-associated protein (IX) Noc2 PF03715.8 KKK21330.1 - 2.5e-122 407.4 0.1 5.7e-122 406.2 0.1 1.6 1 0 0 1 1 1 1 Noc2p family adh_short PF00106.20 KKK21330.1 - 0.09 12.6 2.0 0.46 10.3 0.0 2.4 2 0 0 2 2 2 0 short chain dehydrogenase VPS28 PF03997.7 KKK21331.1 - 5.4e-61 205.4 0.0 6.5e-61 205.2 0.0 1.1 1 0 0 1 1 1 1 VPS28 protein Imm3 PF14425.1 KKK21331.1 - 0.12 12.2 0.7 0.99 9.3 0.1 2.3 2 0 0 2 2 2 0 Immunity protein Imm3 Sugar_tr PF00083.19 KKK21332.1 - 6.1e-84 282.1 18.8 7e-84 281.9 13.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KKK21332.1 - 1.6e-17 63.3 23.0 1.6e-17 63.3 15.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily tRNA-synt_2b PF00587.20 KKK21333.1 - 7.4e-48 162.3 0.0 1.4e-47 161.4 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Fungal_trans PF04082.13 KKK21333.1 - 7.4e-28 97.1 1.5 1.3e-27 96.3 1.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain HGTP_anticodon PF03129.15 KKK21333.1 - 5.3e-05 23.0 0.0 0.00011 22.0 0.0 1.4 1 0 0 1 1 1 1 Anticodon binding domain Glyco_hydro_31 PF01055.21 KKK21334.1 - 1.7e-171 570.9 1.2 2.1e-171 570.6 0.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 KKK21334.1 - 4.7e-11 42.3 2.1 1.5e-10 40.7 1.5 2.0 1 0 0 1 1 1 1 Galactose mutarotase-like Amidohydro_2 PF04909.9 KKK21335.1 - 1.7e-25 90.1 0.0 2.1e-25 89.8 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase ATP-synt_G PF04718.10 KKK21336.1 - 2.6e-32 111.5 0.1 6.1e-32 110.3 0.0 1.6 1 1 1 2 2 2 1 Mitochondrial ATP synthase g subunit Shadoo PF14999.1 KKK21336.1 - 0.011 15.5 1.7 0.016 15.0 1.1 1.3 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective Chorion_2 PF03964.10 KKK21336.1 - 0.55 10.8 8.5 0.28 11.7 4.5 1.6 2 0 0 2 2 2 0 Chorion family 2 ADH_N PF08240.7 KKK21337.1 - 1e-27 96.0 1.1 2.1e-27 95.0 0.8 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KKK21337.1 - 3.5e-12 46.0 0.0 8.5e-12 44.7 0.0 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase S1-like PF14444.1 KKK21337.1 - 0.041 13.5 0.0 0.56 9.9 0.0 2.3 2 0 0 2 2 2 0 S1-like Pyr_redox_3 PF13738.1 KKK21337.1 - 0.14 12.2 0.1 0.24 11.4 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_16 PF10294.4 KKK21338.1 - 6.8e-21 74.4 0.0 1.3e-20 73.5 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 KKK21338.1 - 0.088 13.3 0.0 0.2 12.2 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 KKK21338.1 - 0.13 11.5 0.0 0.26 10.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain DEAD PF00270.24 KKK21339.1 - 2.1e-26 92.3 0.0 5.5e-25 87.8 0.0 2.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KKK21339.1 - 3.2e-23 81.3 0.0 2.4e-22 78.5 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KKK21339.1 - 3.8e-06 26.8 0.0 7.1e-05 22.7 0.0 2.5 1 1 0 2 2 2 1 Type III restriction enzyme, res subunit DUF1253 PF06862.7 KKK21339.1 - 0.0074 14.7 1.2 0.32 9.3 0.0 2.9 3 0 0 3 3 3 1 Protein of unknown function (DUF1253) PNP_UDP_1 PF01048.15 KKK21342.1 - 4.8e-14 51.9 0.0 8.9e-14 51.0 0.0 1.4 1 0 0 1 1 1 1 Phosphorylase superfamily Pkinase PF00069.20 KKK21343.1 - 0.0011 18.1 0.0 0.0023 17.1 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK21343.1 - 0.0014 17.7 0.0 0.0029 16.7 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase P4Ha_N PF08336.6 KKK21343.1 - 0.11 12.2 0.6 0.19 11.5 0.4 1.4 1 0 0 1 1 1 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Pkinase PF00069.20 KKK21344.1 - 1.2e-50 172.1 0.0 1.5e-50 171.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK21344.1 - 5e-28 97.8 0.0 7.2e-28 97.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KKK21344.1 - 0.0087 15.1 0.0 0.024 13.6 0.0 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Gram_pos_anchor PF00746.16 KKK21345.1 - 0.31 10.9 1.5 0.51 10.2 1.1 1.3 1 0 0 1 1 1 0 Gram positive anchor DUF4291 PF14124.1 KKK21346.1 - 2.4e-72 242.3 0.1 2.8e-72 242.1 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4291) Methyltransf_23 PF13489.1 KKK21347.1 - 1.2e-24 86.8 0.0 2.2e-24 85.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KKK21347.1 - 2e-11 43.7 0.0 3e-10 39.8 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KKK21347.1 - 3.2e-10 40.5 0.0 3.5e-09 37.2 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KKK21347.1 - 9.1e-07 29.2 0.0 2e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KKK21347.1 - 3.6e-05 24.1 0.0 0.00024 21.4 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 KKK21347.1 - 0.00087 18.3 0.0 0.018 14.0 0.0 2.2 2 0 0 2 2 2 1 Putative methyltransferase Ubie_methyltran PF01209.13 KKK21347.1 - 0.0018 17.4 0.0 1.2 8.2 0.0 2.7 2 1 0 2 2 2 2 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 KKK21347.1 - 0.0021 18.0 0.0 0.042 13.8 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KKK21347.1 - 0.0049 17.2 0.0 0.026 14.8 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_16 PF10294.4 KKK21347.1 - 0.14 11.6 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase TRM PF02005.11 KKK21347.1 - 0.15 10.9 0.0 0.21 10.4 0.0 1.2 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase MTS PF05175.9 KKK21347.1 - 0.16 11.3 0.0 0.46 9.8 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase small domain PrmA PF06325.8 KKK21347.1 - 0.17 11.0 0.0 0.28 10.2 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DUF2406 PF10295.4 KKK21348.1 - 5.2e-18 65.3 2.0 1.3e-17 64.0 1.4 1.8 1 1 0 1 1 1 1 Uncharacterised protein (DUF2406) Glyco_hydro_72 PF03198.9 KKK21349.1 - 3e-136 453.5 12.1 3.7e-136 453.2 8.4 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.8 KKK21349.1 - 1.8e-24 86.0 5.3 1.8e-24 86.0 3.7 2.1 2 0 0 2 2 2 1 X8 domain Gly_transf_sug PF04488.10 KKK21350.1 - 1.8e-12 47.5 0.1 3.1e-12 46.7 0.1 1.3 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 KKK21350.1 - 0.0022 16.5 0.5 0.0056 15.2 0.0 1.8 3 0 0 3 3 3 1 TcdA/TcdB catalytic glycosyltransferase domain Cupin_3 PF05899.7 KKK21351.1 - 0.042 13.2 0.0 0.06 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF861) ABC_tran PF00005.22 KKK21352.1 - 9.2e-47 158.7 0.0 2.4e-28 99.1 0.0 3.0 2 1 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 KKK21352.1 - 9.8e-33 113.7 18.4 1.7e-16 60.5 2.5 4.6 5 0 0 5 5 5 2 ABC transporter transmembrane region SMC_N PF02463.14 KKK21352.1 - 4.1e-10 39.2 0.3 0.058 12.6 0.0 4.2 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain DUF258 PF03193.11 KKK21352.1 - 1.4e-05 24.3 0.0 0.033 13.3 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_23 PF13476.1 KKK21352.1 - 1.7e-05 25.2 0.0 0.0026 18.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 KKK21352.1 - 7.5e-05 22.2 0.1 0.16 11.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 KKK21352.1 - 0.00012 21.5 0.5 0.52 9.8 0.1 3.0 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF87 PF01935.12 KKK21352.1 - 0.00019 21.3 3.0 0.16 11.7 0.0 3.2 3 0 0 3 3 3 2 Domain of unknown function DUF87 T2SE PF00437.15 KKK21352.1 - 0.00021 20.2 0.0 0.13 11.1 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_16 PF13191.1 KKK21352.1 - 0.0005 20.0 0.6 0.14 12.1 0.0 2.9 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KKK21352.1 - 0.00095 19.3 0.0 2.7 8.1 0.0 3.8 3 0 0 3 3 3 1 AAA domain MMR_HSR1 PF01926.18 KKK21352.1 - 0.002 18.0 0.1 0.39 10.6 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_10 PF12846.2 KKK21352.1 - 0.002 17.6 1.9 0.54 9.6 0.0 2.8 2 1 0 3 3 3 2 AAA-like domain AAA_21 PF13304.1 KKK21352.1 - 0.0031 17.5 1.7 11 5.8 0.0 4.1 5 0 0 5 5 5 0 AAA domain Zeta_toxin PF06414.7 KKK21352.1 - 0.0047 16.0 0.0 1.2 8.1 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin FtsK_SpoIIIE PF01580.13 KKK21352.1 - 0.0047 16.4 0.0 0.93 8.9 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family Miro PF08477.8 KKK21352.1 - 0.0065 16.9 0.1 5.1 7.6 0.0 2.6 2 0 0 2 2 2 1 Miro-like protein DUF2275 PF10039.4 KKK21352.1 - 0.012 15.5 0.8 0.02 14.8 0.0 1.7 2 0 0 2 2 1 0 Predicted integral membrane protein (DUF2275) DUF2075 PF09848.4 KKK21352.1 - 0.043 12.7 0.0 0.65 8.9 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) MobB PF03205.9 KKK21352.1 - 0.055 13.1 0.4 1.2 8.7 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B TrwB_AAD_bind PF10412.4 KKK21352.1 - 0.075 11.6 0.3 0.91 8.0 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain SbcCD_C PF13558.1 KKK21352.1 - 0.088 12.7 0.1 4.6 7.2 0.0 3.0 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.1 KKK21352.1 - 0.23 11.7 0.0 34 4.7 0.0 2.8 2 0 0 2 2 2 0 AAA domain CbiA PF01656.18 KKK21352.1 - 0.23 10.8 0.9 7.7 5.8 0.0 2.7 3 0 0 3 3 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain ADH_N PF08240.7 KKK21353.1 - 7.1e-16 57.9 0.6 1.3e-15 57.1 0.4 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KKK21353.1 - 1.5e-13 50.4 0.2 2.4e-12 46.5 0.1 2.2 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KKK21353.1 - 6.4e-07 30.3 0.0 1.3e-06 29.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.9 KKK21353.1 - 0.0021 17.4 0.0 0.0036 16.7 0.0 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.14 KKK21353.1 - 0.0043 16.2 0.0 0.0076 15.4 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_11 PF08241.7 KKK21353.1 - 0.016 15.6 0.0 0.048 14.1 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain MTS PF05175.9 KKK21353.1 - 0.026 13.9 0.0 0.046 13.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_18 PF12847.2 KKK21353.1 - 0.035 14.7 0.0 0.061 13.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_26 PF13659.1 KKK21353.1 - 0.057 13.4 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain HpcH_HpaI PF03328.9 KKK21354.1 - 4.3e-35 120.6 0.0 5.4e-35 120.2 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PK PF00224.16 KKK21354.1 - 0.034 12.7 1.2 0.35 9.4 0.5 1.9 1 1 1 2 2 2 0 Pyruvate kinase, barrel domain Glyco_hydro_11 PF00457.12 KKK21355.1 - 6.8e-74 247.1 20.1 6.8e-74 247.1 13.9 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 11 CBM_1 PF00734.13 KKK21355.1 - 1.1e-11 44.1 13.1 1.1e-11 44.1 9.0 2.4 3 0 0 3 3 3 1 Fungal cellulose binding domain Methyltransf_2 PF00891.13 KKK21356.1 - 9.9e-26 90.3 0.0 1.4e-25 89.9 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 KKK21356.1 - 0.0001 22.8 0.0 0.00026 21.5 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 KKK21356.1 - 0.00018 21.2 0.3 0.02 14.6 0.0 2.6 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_12 PF08242.7 KKK21356.1 - 0.043 14.2 0.0 0.19 12.2 0.0 2.1 3 0 0 3 3 3 0 Methyltransferase domain MFS_1 PF07690.11 KKK21357.1 - 1.2e-37 129.4 24.4 1.2e-37 129.4 16.9 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KKK21357.1 - 1e-14 54.0 13.5 2.7e-14 52.6 9.3 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter OATP PF03137.15 KKK21357.1 - 0.051 11.6 7.3 0.028 12.4 0.5 2.6 3 0 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family ADH_zinc_N PF00107.21 KKK21358.1 - 3.2e-11 42.9 0.1 5.4e-11 42.1 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KKK21358.1 - 5.5e-09 35.7 0.0 2.8e-08 33.4 0.0 2.0 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain RmlD_sub_bind PF04321.12 KKK21358.1 - 0.046 12.5 0.2 0.072 11.9 0.2 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain CutC PF03932.9 KKK21358.1 - 0.16 11.2 0.1 0.29 10.3 0.0 1.3 1 0 0 1 1 1 0 CutC family FAD_binding_4 PF01565.18 KKK21359.1 - 5.2e-26 90.7 3.3 8.7e-26 90.0 2.3 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KKK21359.1 - 3.1e-15 55.8 0.1 5.6e-15 54.9 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like FAD-oxidase_C PF02913.14 KKK21359.1 - 0.14 11.4 0.1 5.3 6.2 0.0 2.2 2 0 0 2 2 2 0 FAD linked oxidases, C-terminal domain Glycos_transf_1 PF00534.15 KKK21360.1 - 1.5e-08 34.2 0.0 3.5e-08 33.0 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferases group 1 Pkinase PF00069.20 KKK21399.1 - 2.3e-06 26.9 0.1 2.7e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 KKK21399.1 - 0.0013 17.8 0.2 0.0018 17.3 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KKK21399.1 - 0.026 14.2 0.7 0.28 10.8 0.2 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family EcKinase PF02958.15 KKK21399.1 - 0.042 12.9 0.2 2.5 7.1 0.0 2.1 1 1 0 2 2 2 0 Ecdysteroid kinase Pkinase PF00069.20 KKK21401.1 - 5.3e-15 55.2 0.0 8.5e-15 54.6 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK21401.1 - 0.00025 20.2 0.0 0.00073 18.6 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase DAO PF01266.19 KKK21402.1 - 2e-41 142.1 0.1 3.1e-41 141.4 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Antimicrobial12 PF08107.6 KKK21402.1 - 0.039 13.5 0.5 0.11 12.0 0.3 1.8 1 0 0 1 1 1 0 Pleurocidin family Thi4 PF01946.12 KKK21402.1 - 0.045 12.8 0.0 0.091 11.8 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.1 KKK21402.1 - 0.12 12.4 0.0 12 5.8 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HhH-GPD PF00730.20 KKK21414.1 - 6.5e-11 42.4 0.0 1.1e-10 41.7 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein Ecm33 PF12454.3 KKK21415.1 - 3.8e-14 52.2 1.1 3.8e-14 52.2 0.8 2.1 2 0 0 2 2 2 1 GPI-anchored cell wall organization protein LRR_5 PF13306.1 KKK21415.1 - 1.2e-07 31.5 0.3 0.0087 15.7 0.1 2.6 1 1 1 2 2 2 2 Leucine rich repeats (6 copies) Recep_L_domain PF01030.19 KKK21415.1 - 0.00026 20.9 4.1 3.1 7.7 0.0 4.4 1 1 4 5 5 5 3 Receptor L domain G-patch PF01585.18 KKK21474.1 - 1.4e-05 24.7 0.0 0.00021 20.9 0.0 2.5 1 1 0 1 1 1 1 G-patch domain MIP-T3 PF10243.4 KKK21474.1 - 0.088 11.2 45.0 0.12 10.8 31.2 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 SR-25 PF10500.4 KKK21474.1 - 0.12 11.8 45.6 0.2 11.0 31.6 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CDC27 PF09507.5 KKK21474.1 - 0.19 10.9 44.5 0.22 10.6 30.8 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 SURF2 PF05477.6 KKK21474.1 - 1.4 8.0 34.3 2.4 7.2 23.8 1.4 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) Macoilin PF09726.4 KKK21474.1 - 2.5 6.2 27.5 3.8 5.6 19.1 1.2 1 0 0 1 1 1 0 Transmembrane protein Syja_N PF02383.13 KKK21475.1 - 2.3e-82 276.2 0.0 3.2e-82 275.8 0.0 1.1 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.18 KKK21475.1 - 4e-25 89.1 0.5 9.3e-25 87.9 0.4 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Kinesin PF00225.18 KKK21476.1 - 3.2e-98 328.5 0.0 7.6e-98 327.2 0.0 1.6 1 0 0 1 1 1 1 Kinesin motor domain DAGAT PF03982.8 KKK21477.1 - 9.4e-87 290.4 0.0 1.2e-86 290.1 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Rer1 PF03248.8 KKK21477.1 - 0.44 10.1 2.6 0.76 9.3 1.8 1.3 1 0 0 1 1 1 0 Rer1 family IGR PF09597.5 KKK21478.1 - 2.9e-24 84.7 0.1 4.7e-24 84.0 0.1 1.4 1 0 0 1 1 1 1 IGR protein motif Chorion_2 PF03964.10 KKK21478.1 - 0.0056 17.2 2.5 0.0091 16.5 1.7 1.4 1 0 0 1 1 1 1 Chorion family 2 Herpes_capsid PF06112.6 KKK21478.1 - 0.11 12.5 6.3 0.18 11.8 4.3 1.4 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein SSP160 PF06933.6 KKK21478.1 - 5.4 4.8 11.2 8.1 4.2 7.7 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF515 PF04415.7 KKK21478.1 - 6.6 4.8 7.1 8.7 4.4 4.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Pkinase PF00069.20 KKK21479.1 - 4.8e-64 216.0 0.0 5.5e-64 215.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK21479.1 - 2.1e-33 115.5 0.0 3.1e-33 114.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KKK21479.1 - 0.034 13.1 0.0 0.057 12.3 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Pkinase PF00069.20 KKK21480.1 - 8.8e-69 231.5 0.0 8.8e-68 228.2 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK21480.1 - 7.3e-35 120.2 0.0 4.5e-29 101.3 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase FHA PF00498.21 KKK21480.1 - 7.2e-14 51.6 0.0 1.5e-13 50.6 0.0 1.6 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.1 KKK21480.1 - 5.5e-09 35.3 0.3 0.00081 18.4 0.1 3.0 2 1 1 3 3 3 2 Kinase-like APH PF01636.18 KKK21480.1 - 0.0002 21.1 0.1 0.0011 18.6 0.1 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 KKK21480.1 - 0.004 15.9 0.0 0.006 15.4 0.0 1.1 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase RIO1 PF01163.17 KKK21480.1 - 0.0066 15.8 0.1 0.019 14.3 0.0 1.7 2 0 0 2 2 2 1 RIO1 family Kdo PF06293.9 KKK21480.1 - 0.062 12.3 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family p450 PF00067.17 KKK21481.1 - 7.2e-77 258.8 0.0 8.4e-77 258.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 PI3_PI4_kinase PF00454.22 KKK21482.1 - 6.5e-36 123.9 0.1 4.7e-35 121.1 0.0 2.5 3 1 0 3 3 3 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 KKK21482.1 - 2.1e-24 85.7 0.1 4.4e-24 84.6 0.1 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) SAPS PF04499.10 KKK21483.1 - 0.17 10.4 4.3 0.28 9.7 3.0 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Mitofilin PF09731.4 KKK21483.1 - 1.1 7.8 22.3 0.0041 15.8 8.8 1.8 2 0 0 2 2 2 0 Mitochondrial inner membrane protein DUF763 PF05559.6 KKK21483.1 - 1.6 7.6 5.9 2.2 7.1 4.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF763) Asp-B-Hydro_N PF05279.6 KKK21483.1 - 3.1 7.5 21.4 6.4 6.5 14.8 1.4 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Hexapep PF00132.19 KKK21493.1 - 7.7e-07 28.3 1.2 4.9e-06 25.8 0.3 2.2 2 0 0 2 2 2 1 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 KKK21493.1 - 0.0009 19.3 0.0 0.0026 17.8 0.0 1.7 1 1 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.1 KKK21493.1 - 0.027 14.0 1.0 0.099 12.2 0.7 2.0 1 1 0 1 1 1 0 Hexapeptide repeat of succinyl-transferase GTP_EFTU PF00009.22 KKK21493.1 - 0.1 11.9 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain Spt20 PF12090.3 KKK21495.1 - 5.6e-51 172.4 1.4 5.6e-51 172.4 1.0 5.9 4 2 0 4 4 4 1 Spt20 family Pkinase PF00069.20 KKK21515.1 - 1.5e-32 112.7 0.0 2.4e-32 112.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK21515.1 - 4.6e-24 84.8 0.0 7.5e-24 84.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase BatA PF07584.6 KKK21523.1 - 0.54 10.4 3.4 18 5.6 0.1 2.9 2 0 0 2 2 2 0 Aerotolerance regulator N-terminal CorA PF01544.13 KKK21525.1 - 0.0004 19.4 0.8 0.00078 18.5 0.6 1.4 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Metallophos PF00149.23 KKK21526.1 - 1.1e-42 145.7 1.4 1.9e-42 144.9 0.9 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.1 KKK21526.1 - 1.1e-15 57.4 0.2 4.9e-15 55.3 0.1 2.2 2 0 0 2 2 2 1 Iron/zinc purple acid phosphatase-like protein C PhoD PF09423.5 KKK21526.1 - 2.8e-10 39.3 0.4 4.7e-08 32.0 0.2 2.1 2 0 0 2 2 2 2 PhoD-like phosphatase Metallophos_2 PF12850.2 KKK21526.1 - 0.0057 16.5 0.1 0.037 13.8 0.0 2.4 1 1 1 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain Mannosyl_trans3 PF11051.3 KKK21527.1 - 5.4e-65 219.4 0.0 7.2e-65 219.0 0.0 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative MAPEG PF01124.13 KKK21527.1 - 2e-18 66.2 0.1 3.4e-18 65.4 0.1 1.4 1 0 0 1 1 1 1 MAPEG family Sulfatase PF00884.18 KKK21528.1 - 1.1e-65 221.8 1.0 1.4e-65 221.4 0.7 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 KKK21528.1 - 0.019 14.3 5.7 1.1 8.4 4.0 2.5 2 1 0 2 2 2 0 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.12 KKK21528.1 - 0.27 9.6 0.2 0.5 8.7 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF229) DUF2235 PF09994.4 KKK21529.1 - 2.8e-66 223.7 0.0 4.1e-66 223.1 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Caps_synth PF05704.7 KKK21529.1 - 1.2e-07 31.2 0.0 2.7e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein Gly_transf_sug PF04488.10 KKK21529.1 - 0.0066 16.8 0.0 0.015 15.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Abhydrolase_5 PF12695.2 KKK21529.1 - 0.052 13.2 0.0 0.13 12.0 0.0 1.7 1 0 0 1 1 1 0 Alpha/beta hydrolase family MFS_1 PF07690.11 KKK21530.1 - 8.4e-41 139.8 34.9 8.4e-41 139.8 24.2 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KKK21530.1 - 3.3e-09 35.8 13.0 3.3e-09 35.8 9.0 3.1 3 0 0 3 3 3 1 Sugar (and other) transporter Aldo_ket_red PF00248.16 KKK21531.1 - 4.5e-53 179.9 0.0 5.1e-53 179.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family GHMP_kinases_N PF00288.21 KKK21533.1 - 2.8e-11 43.3 0.4 8.2e-11 41.8 0.3 1.8 1 0 0 1 1 1 1 GHMP kinases N terminal domain Dicer_dimer PF03368.9 KKK21533.1 - 0.0064 16.2 0.0 0.013 15.2 0.0 1.6 1 0 0 1 1 1 1 Dicer dimerisation domain Ndc1_Nup PF09531.5 KKK21534.1 - 1.6e-166 555.2 7.3 3.7e-112 375.7 3.9 2.0 1 1 1 2 2 2 2 Nucleoporin protein Ndc1-Nup zf-C2H2_4 PF13894.1 KKK21535.1 - 0.00024 21.2 23.5 0.28 11.5 0.4 5.1 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2H2 PF00096.21 KKK21535.1 - 0.011 16.0 25.9 0.041 14.2 1.2 4.9 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-CHCC PF10276.4 KKK21535.1 - 0.35 10.7 3.6 5.1 7.0 0.1 2.5 2 0 0 2 2 2 0 Zinc-finger domain zf-C2H2_2 PF12756.2 KKK21535.1 - 1.8 8.7 12.8 0.54 10.3 2.0 3.2 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 KKK21535.1 - 2.5 8.3 16.8 0.036 14.2 2.5 3.8 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding Cyto_heme_lyase PF01265.12 KKK21536.1 - 4.2e-79 265.7 0.1 5.2e-78 262.2 0.1 1.9 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase Syntaxin_2 PF14523.1 KKK21537.1 - 8.3e-25 86.7 3.0 8.3e-25 86.7 2.1 2.6 2 1 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.14 KKK21537.1 - 1.6e-17 62.8 1.8 1.6e-17 62.8 1.2 2.2 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 KKK21537.1 - 0.00077 19.5 0.3 0.00077 19.5 0.2 2.9 1 1 1 2 2 2 1 Syntaxin Synaptobrevin PF00957.16 KKK21537.1 - 0.015 14.8 0.1 0.061 12.9 0.1 2.0 1 0 0 1 1 1 0 Synaptobrevin Toxin_61 PF15538.1 KKK21537.1 - 0.065 13.2 0.7 0.2 11.6 0.7 1.6 2 0 0 2 2 2 0 Putative toxin 61 OmpH PF03938.9 KKK21537.1 - 0.29 11.0 15.2 0.45 10.4 10.5 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF2951 PF11166.3 KKK21537.1 - 0.92 9.3 5.0 1.4 8.7 0.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2951) zf-H2C2_2 PF13465.1 KKK21556.1 - 1.4e-17 62.9 28.1 6.8e-07 29.2 1.4 4.6 4 1 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.21 KKK21556.1 - 5e-16 58.0 39.2 9.7e-05 22.4 3.6 4.3 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KKK21556.1 - 1.2e-05 25.3 36.5 0.022 15.0 3.0 4.3 4 0 0 4 4 4 4 C2H2-type zinc finger ETF_QO PF05187.8 KKK21556.1 - 1.2 9.1 5.1 7.6 6.5 0.1 2.4 2 0 0 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase PAT1 PF09770.4 KKK21556.1 - 1.7 6.8 19.9 1.9 6.6 13.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 adh_short PF00106.20 KKK21557.1 - 1.1e-06 28.6 0.0 5.3e-05 23.1 0.0 2.7 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KKK21557.1 - 0.081 12.5 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 KR domain Aminotran_1_2 PF00155.16 KKK21558.1 - 1.3e-28 100.0 0.0 7.3e-28 97.5 0.0 1.9 1 1 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 KKK21558.1 - 0.16 11.0 0.0 0.28 10.2 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase Suc_Fer-like PF06999.7 KKK21559.1 - 1.5e-35 123.2 0.0 2.1e-35 122.8 0.0 1.2 1 0 0 1 1 1 1 Sucrase/ferredoxin-like DUF4129 PF13559.1 KKK21559.1 - 0.00019 21.3 0.1 0.00019 21.3 0.0 2.3 3 0 0 3 3 3 1 Domain of unknown function (DUF4129) PH_10 PF15411.1 KKK21560.1 - 1.4e-30 105.8 0.0 2.3e-30 105.1 0.0 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain PB1 PF00564.19 KKK21561.1 - 2.3e-10 39.9 0.1 2.7e-10 39.7 0.1 1.1 1 0 0 1 1 1 1 PB1 domain 4_1_CTD PF05902.8 KKK21561.1 - 0.15 12.1 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 4.1 protein C-terminal domain (CTD) G_glu_transpept PF01019.16 KKK21571.1 - 6.9e-156 519.6 0.2 9.4e-156 519.2 0.2 1.2 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase TPP_enzyme_N PF02776.13 KKK21571.1 - 3.6e-38 130.7 0.0 7.7e-38 129.6 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain ADH_N PF08240.7 KKK21571.1 - 1.4e-28 98.8 7.2 3.4e-28 97.5 5.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KKK21571.1 - 8.6e-18 64.1 0.5 3.3e-17 62.2 0.3 2.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase TPP_enzyme_M PF00205.17 KKK21571.1 - 2.1e-17 63.1 0.0 4.4e-17 62.1 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 KKK21571.1 - 9.4e-17 60.9 0.1 2.8e-16 59.4 0.0 1.8 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain ADH_zinc_N_2 PF13602.1 KKK21571.1 - 0.00091 20.1 0.5 0.0035 18.2 0.3 2.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF3357 PF11837.3 KKK21571.1 - 0.08 12.7 0.2 0.18 11.6 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) Git3 PF11710.3 KKK21572.1 - 3e-38 131.4 17.6 6.2e-38 130.4 12.2 1.5 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Git3_C PF11970.3 KKK21572.1 - 2.5e-14 52.7 0.0 9.1e-14 50.9 0.0 2.0 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 C-term HhH-GPD PF00730.20 KKK21573.1 - 1.7e-07 31.4 0.0 8.8e-07 29.1 0.0 2.1 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein Ribosomal_L24e PF01246.15 KKK21592.1 - 5.6e-25 86.9 0.8 5.6e-25 86.9 0.6 2.0 2 0 0 2 2 2 1 Ribosomal protein L24e zf-FCS PF06467.9 KKK21592.1 - 0.041 13.5 1.6 0.087 12.4 1.1 1.5 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif Fungal_trans PF04082.13 KKK21593.1 - 8.3e-33 113.3 0.1 5e-32 110.7 0.0 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK21593.1 - 6.7e-10 38.7 13.1 1.2e-09 37.8 9.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MSA-2c PF12238.3 KKK21593.1 - 0.88 9.1 3.8 0.47 10.0 0.1 2.1 2 0 0 2 2 2 0 Merozoite surface antigen 2c DnaJ PF00226.26 KKK21594.1 - 8.7e-08 31.7 0.1 1.2e-07 31.2 0.1 1.2 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.8 KKK21594.1 - 2.2e-07 30.7 0.1 2.7e-07 30.4 0.0 1.4 1 1 0 1 1 1 1 Pam16 DUF2648 PF10855.3 KKK21594.1 - 0.094 12.1 1.9 0.38 10.2 1.3 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF2648) DUF3918 PF13056.1 KKK21594.1 - 7.7 5.9 12.4 0.15 11.3 0.7 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3918) AAA PF00004.24 KKK21595.1 - 3.2e-43 147.0 0.0 9.3e-43 145.5 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) FtsH_ext PF06480.10 KKK21595.1 - 1.2e-12 47.9 0.1 2.8e-12 46.7 0.1 1.7 1 0 0 1 1 1 1 FtsH Extracellular AAA_5 PF07728.9 KKK21595.1 - 4.7e-05 23.1 0.0 0.00016 21.3 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KKK21595.1 - 0.0002 21.5 0.0 0.15 12.1 0.1 2.9 3 0 0 3 3 3 1 AAA domain AAA_17 PF13207.1 KKK21595.1 - 0.0036 18.1 0.0 0.008 16.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 KKK21595.1 - 0.0053 15.5 0.1 0.0089 14.7 0.1 1.2 1 0 0 1 1 1 1 TIP49 C-terminus AAA_16 PF13191.1 KKK21595.1 - 0.0081 16.1 0.3 0.13 12.2 0.1 2.4 1 1 1 2 2 2 1 AAA ATPase domain DUF935 PF06074.7 KKK21595.1 - 0.0084 14.8 0.2 0.0084 14.8 0.2 1.9 2 1 1 3 3 3 1 Protein of unknown function (DUF935) RuvB_N PF05496.7 KKK21595.1 - 0.0096 14.9 0.0 0.022 13.8 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 KKK21595.1 - 0.017 14.8 0.8 0.017 14.8 0.6 2.4 2 0 0 2 2 2 0 Part of AAA domain AAA_14 PF13173.1 KKK21595.1 - 0.02 14.8 0.0 0.054 13.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.9 KKK21595.1 - 0.026 14.4 0.0 0.097 12.5 0.0 2.0 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.12 KKK21595.1 - 0.032 13.6 0.2 0.07 12.5 0.1 1.5 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA_33 PF13671.1 KKK21595.1 - 0.036 13.9 0.0 0.27 11.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 KKK21595.1 - 0.044 13.1 0.8 0.14 11.5 0.3 1.9 1 1 1 2 2 2 0 AAA domain Serinc PF03348.10 KKK21595.1 - 0.066 11.9 0.1 0.095 11.3 0.1 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) AAA_11 PF13086.1 KKK21595.1 - 0.11 12.0 0.9 11 5.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain GTP_EFTU PF00009.22 KKK21602.1 - 1.9e-43 148.1 0.0 3.2e-43 147.3 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 KKK21602.1 - 2.4e-19 69.3 0.0 6.1e-19 68.0 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 KKK21602.1 - 1.2e-06 28.5 0.4 3e-06 27.2 0.3 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KKK21602.1 - 0.0074 16.2 0.0 0.02 14.8 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase Mitofilin PF09731.4 KKK21602.1 - 0.41 9.2 13.0 0.59 8.7 9.0 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein G-alpha PF00503.15 KKK21602.1 - 1.6 7.2 8.9 6.5 5.3 6.2 1.9 1 1 0 1 1 1 0 G-protein alpha subunit Mcm10 PF09332.6 KKK21602.1 - 9 5.5 11.5 15 4.8 8.0 1.2 1 0 0 1 1 1 0 Mcm10 replication factor WGG PF10273.4 KKK21603.1 - 1.4e-30 105.2 0.3 2.2e-30 104.5 0.2 1.3 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 NOA36 PF06524.7 KKK21603.1 - 0.008 15.4 1.7 0.011 15.0 1.2 1.1 1 0 0 1 1 1 1 NOA36 protein Nro1 PF12753.2 KKK21603.1 - 0.27 10.1 2.8 0.36 9.7 1.9 1.2 1 0 0 1 1 1 0 Nuclear pore complex subunit Nro1 RXT2_N PF08595.6 KKK21603.1 - 0.65 9.7 4.5 1.1 9.0 3.1 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal RRP7 PF12923.2 KKK21603.1 - 1.2 9.1 5.7 4 7.4 3.5 2.0 1 1 1 2 2 2 0 Ribosomal RNA-processing protein 7 (RRP7) DUF4611 PF15387.1 KKK21603.1 - 4.5 7.4 10.3 2.4 8.3 3.7 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4611) Nop14 PF04147.7 KKK21603.1 - 4.9 4.9 9.4 5.3 4.8 6.5 1.0 1 0 0 1 1 1 0 Nop14-like family Med13_C PF06333.7 KKK21604.1 - 8.4e-118 393.5 0.0 1.3e-117 392.9 0.0 1.3 1 0 0 1 1 1 1 Mediator complex subunit 13 C-terminal Med13_N PF11597.3 KKK21604.1 - 2e-83 280.3 0.0 3.3e-83 279.6 0.0 1.3 1 0 0 1 1 1 1 Mediator complex subunit 13 N-terminal Ran-binding PF05508.6 KKK21605.1 - 5.1e-118 393.3 0.8 6.6e-118 393.0 0.6 1.1 1 0 0 1 1 1 1 RanGTP-binding protein ATG13 PF10033.4 KKK21606.1 - 1.5e-75 253.6 0.0 2.3e-75 253.0 0.0 1.3 1 0 0 1 1 1 1 Autophagy-related protein 13 NUC153 PF08159.7 KKK21608.1 - 4.1e-12 45.4 0.4 9.3e-12 44.3 0.3 1.6 1 0 0 1 1 1 1 NUC153 domain WD40 PF00400.27 KKK21608.1 - 1.6e-07 30.9 0.0 0.012 15.5 0.0 4.3 5 0 0 5 5 5 3 WD domain, G-beta repeat Ribosomal_60s PF00428.14 KKK21608.1 - 1.6 9.1 6.9 4.3 7.7 4.8 1.7 1 0 0 1 1 1 0 60s Acidic ribosomal protein RCC1 PF00415.13 KKK21609.1 - 7.4e-23 80.5 0.5 9e-06 25.8 0.0 6.0 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.26 KKK21609.1 - 3e-15 56.1 0.2 8.6e-09 35.3 0.0 2.7 2 0 0 2 2 2 2 BTB/POZ domain RCC1_2 PF13540.1 KKK21609.1 - 5.6e-13 48.1 3.3 7.3e-09 35.0 0.2 4.0 3 0 0 3 3 3 2 Regulator of chromosome condensation (RCC1) repeat Ank_4 PF13637.1 KKK21609.1 - 2.4e-05 24.6 0.2 0.00035 21.0 0.1 2.5 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 KKK21609.1 - 0.00093 19.2 0.3 2.2 8.7 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 KKK21609.1 - 0.0026 18.0 0.0 0.0075 16.5 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KKK21609.1 - 0.14 12.4 0.4 3.4 8.0 0.1 2.9 2 1 1 3 3 3 0 Ankyrin repeats (many copies) VHS PF00790.14 KKK21610.1 - 1e-40 138.6 0.7 1.2e-39 135.1 0.0 2.2 2 0 0 2 2 2 1 VHS domain FYVE PF01363.16 KKK21610.1 - 2.4e-16 59.3 1.4 3.9e-16 58.7 0.9 1.3 1 0 0 1 1 1 1 FYVE zinc finger UIM PF02809.15 KKK21610.1 - 0.00021 20.6 11.3 0.0038 16.6 1.2 2.9 2 0 0 2 2 2 2 Ubiquitin interaction motif zf-DHHC PF01529.15 KKK21610.1 - 0.022 14.1 0.2 0.046 13.1 0.1 1.4 1 0 0 1 1 1 0 DHHC palmitoyltransferase FYVE_2 PF02318.11 KKK21610.1 - 0.054 13.3 0.4 0.11 12.3 0.3 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger UCH PF00443.24 KKK21611.1 - 6.3e-54 182.8 0.0 9.4e-54 182.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KKK21611.1 - 1.2e-30 106.9 0.0 2.2e-30 106.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Rhodanese PF00581.15 KKK21611.1 - 0.00082 19.6 0.0 0.0022 18.3 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain BSD PF03909.12 KKK21612.1 - 1.4e-15 56.7 1.4 2.8e-15 55.8 1.0 1.5 1 0 0 1 1 1 1 BSD domain Legionella_OMP PF05150.7 KKK21612.1 - 0.08 12.0 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Legionella pneumophila major outer membrane protein precursor Suf PF05843.9 KKK21612.1 - 0.27 10.8 2.4 0.59 9.8 1.7 1.5 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) KH_1 PF00013.24 KKK21613.1 - 6.9e-92 301.0 18.9 8.9e-12 44.4 0.3 13.7 13 1 0 13 13 13 9 KH domain KH_3 PF13014.1 KKK21613.1 - 1.1e-66 219.6 21.8 3.1e-09 36.2 0.7 13.5 14 1 0 14 14 14 10 KH domain KH_2 PF07650.12 KKK21613.1 - 7.1e-11 41.5 25.2 0.0058 16.1 0.3 7.9 6 1 1 7 7 7 4 KH domain SLS PF14611.1 KKK21613.1 - 6e-10 38.8 0.1 0.018 14.4 0.0 7.1 6 3 1 7 7 7 2 Mitochondrial inner-membrane-bound regulator KH_5 PF13184.1 KKK21613.1 - 0.47 10.2 9.2 25 4.7 0.2 5.8 7 0 0 7 7 7 0 NusA-like KH domain Cyt-b5 PF00173.23 KKK21614.1 - 3.8e-23 81.0 0.1 4.8e-23 80.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Pkinase PF00069.20 KKK21615.1 - 1.4e-70 237.4 0.0 2.4e-70 236.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK21615.1 - 8.3e-45 152.8 0.0 1.3e-44 152.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 KKK21615.1 - 6.9e-14 52.0 0.1 3.5e-13 49.7 0.1 2.3 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.1 KKK21615.1 - 1.5e-06 27.4 0.0 2.3e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like DSHCT PF08148.7 KKK21615.1 - 0.11 11.6 0.0 0.21 10.8 0.0 1.4 1 0 0 1 1 1 0 DSHCT (NUC185) domain APH PF01636.18 KKK21615.1 - 0.73 9.5 9.2 0.2 11.3 0.1 3.1 2 1 1 3 3 3 0 Phosphotransferase enzyme family DUF2569 PF10754.4 KKK21617.1 - 0.038 14.2 0.1 0.04 14.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2569) DUF1469 PF07332.6 KKK21617.1 - 0.046 13.4 0.0 0.061 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) DUF669 PF05037.8 KKK21617.1 - 0.097 12.5 0.0 0.12 12.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF669) DUF221 PF02714.10 KKK21617.1 - 0.13 11.0 1.0 0.14 10.9 0.7 1.0 1 0 0 1 1 1 0 Domain of unknown function DUF221 IlvGEDA_leader PF08046.6 KKK21617.1 - 0.3 10.2 4.0 0.46 9.6 2.8 1.3 1 0 0 1 1 1 0 IlvGEDA operon leader peptide TMEM190 PF15431.1 KKK21617.1 - 0.36 10.7 4.2 0.47 10.3 2.9 1.3 1 0 0 1 1 1 0 Transmembrane protein 190 DUF4381 PF14316.1 KKK21617.1 - 6.4 6.8 7.1 4.6 7.3 3.6 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4381) Amidase PF01425.16 KKK21618.1 - 3.5e-80 270.0 0.0 4.7e-80 269.5 0.0 1.2 1 0 0 1 1 1 1 Amidase HMGL-like PF00682.14 KKK21619.1 - 2.2e-37 128.9 0.0 2.6e-37 128.7 0.0 1.1 1 0 0 1 1 1 1 HMGL-like SLAC1 PF03595.12 KKK21621.1 - 1.1e-110 369.4 53.8 1.2e-110 369.2 37.3 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel AT_hook PF02178.14 KKK21622.1 - 0.0087 15.6 37.6 0.054 13.1 1.3 4.7 4 0 0 4 4 4 3 AT hook motif zf-DHHC PF01529.15 KKK21624.1 - 1.1e-36 125.8 10.9 1.1e-36 125.8 7.5 2.3 2 0 0 2 2 2 1 DHHC palmitoyltransferase Ank PF00023.25 KKK21624.1 - 2.4e-36 121.7 4.5 2e-10 39.9 0.0 5.6 5 0 0 5 5 5 5 Ankyrin repeat Ank_2 PF12796.2 KKK21624.1 - 4.1e-36 123.1 0.2 1.3e-16 60.7 0.0 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KKK21624.1 - 3.6e-28 96.9 6.6 2.2e-09 37.2 0.0 4.9 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_4 PF13637.1 KKK21624.1 - 1.2e-26 92.5 12.1 1.3e-08 35.0 0.3 4.7 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 KKK21624.1 - 8.1e-25 84.4 3.3 1.4e-08 34.1 0.0 5.6 5 0 0 5 5 5 4 Ankyrin repeat Cyclin PF08613.6 KKK21625.1 - 2.5e-34 118.8 0.0 3.1e-34 118.5 0.0 1.2 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 KKK21625.1 - 0.0013 18.2 0.0 0.0021 17.5 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain ABC_tran PF00005.22 KKK21636.1 - 4.5e-47 159.8 0.0 5.8e-30 104.3 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 KKK21636.1 - 1.6e-33 116.3 30.3 3.6e-18 65.9 10.7 3.6 3 1 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.14 KKK21636.1 - 4.4e-12 45.7 0.2 0.0012 18.1 0.0 4.3 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 KKK21636.1 - 7.9e-06 25.3 0.0 0.17 11.2 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_23 PF13476.1 KKK21636.1 - 1.7e-05 25.2 1.7 0.0064 16.8 0.0 2.9 3 0 0 3 3 3 1 AAA domain T2SE PF00437.15 KKK21636.1 - 0.00013 21.0 0.0 0.12 11.2 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_22 PF13401.1 KKK21636.1 - 0.00014 22.0 0.0 1.7 8.8 0.0 3.4 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.1 KKK21636.1 - 0.00022 21.2 1.8 0.041 13.8 0.1 2.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.1 KKK21636.1 - 0.00025 20.5 0.4 0.78 9.3 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.1 KKK21636.1 - 0.0014 18.6 0.5 0.24 11.2 0.0 3.5 2 2 0 3 3 3 1 AAA domain AAA_10 PF12846.2 KKK21636.1 - 0.0028 17.1 0.0 3.5 6.9 0.0 2.7 2 1 0 2 2 2 2 AAA-like domain AAA_17 PF13207.1 KKK21636.1 - 0.0035 18.1 0.0 0.85 10.4 0.0 2.8 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 KKK21636.1 - 0.0051 16.7 0.0 0.28 11.1 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase DUF258 PF03193.11 KKK21636.1 - 0.0063 15.7 0.0 1.8 7.7 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 DUF87 PF01935.12 KKK21636.1 - 0.011 15.5 2.1 0.31 10.8 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF87 DUF2075 PF09848.4 KKK21636.1 - 0.022 13.7 0.0 1.3 7.9 0.0 2.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) SbcCD_C PF13558.1 KKK21636.1 - 0.025 14.4 0.0 4.7 7.2 0.0 3.0 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Zeta_toxin PF06414.7 KKK21636.1 - 0.029 13.4 0.0 1.8 7.5 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin Miro PF08477.8 KKK21636.1 - 0.036 14.5 0.0 6.2 7.3 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein IstB_IS21 PF01695.12 KKK21636.1 - 0.044 13.2 0.0 0.37 10.1 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein NB-ARC PF00931.17 KKK21636.1 - 0.11 11.3 0.0 5.5 5.7 0.0 2.6 3 0 0 3 3 3 0 NB-ARC domain AAA_30 PF13604.1 KKK21636.1 - 0.12 11.8 0.4 11 5.5 0.0 2.8 3 0 0 3 3 3 0 AAA domain Pox_A32 PF04665.7 KKK21636.1 - 0.22 10.8 0.3 2.7 7.2 0.0 2.2 2 0 0 2 2 2 0 Poxvirus A32 protein GFA PF04828.9 KKK21637.1 - 3.7e-20 71.6 0.2 5e-20 71.2 0.1 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme PTR2 PF00854.16 KKK21638.1 - 2e-55 188.1 8.2 3.1e-55 187.4 5.7 1.3 1 0 0 1 1 1 1 POT family p450 PF00067.17 KKK21640.1 - 3.9e-42 144.3 0.0 6.9e-42 143.5 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 IF4E PF01652.13 KKK21641.1 - 6.6e-59 198.1 0.0 8.3e-59 197.8 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E RIIa PF02197.12 KKK21641.1 - 0.045 13.1 0.0 0.089 12.2 0.0 1.4 1 0 0 1 1 1 0 Regulatory subunit of type II PKA R-subunit Mpv17_PMP22 PF04117.7 KKK21642.1 - 3.5e-24 84.1 1.4 6.2e-24 83.4 0.9 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family Ribosomal_S5 PF00333.15 KKK21643.1 - 2.3e-28 97.7 3.1 4.4e-28 96.8 1.4 2.0 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 KKK21643.1 - 7.5e-21 73.1 0.0 1.5e-20 72.2 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain FXR1P_C PF12235.3 KKK21643.1 - 2.4 8.2 10.5 4.2 7.4 7.3 1.3 1 0 0 1 1 1 0 Fragile X-related 1 protein C terminal Glyco_hydro_98M PF08306.6 KKK21644.1 - 0.029 13.0 0.0 0.037 12.7 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 98 Spc7_N PF15402.1 KKK21645.1 - 0.035 12.1 5.5 0.048 11.6 3.8 1.1 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 DUF2039 PF10217.4 KKK21645.1 - 2 8.5 5.2 4 7.5 3.6 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) Tnp_zf-ribbon_2 PF13842.1 KKK21645.1 - 6.2 7.3 7.2 12 6.3 5.0 1.5 1 0 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon AIG2 PF06094.7 KKK21648.1 - 5.6e-07 29.9 0.0 1.1e-06 29.0 0.0 1.4 1 0 0 1 1 1 1 AIG2-like family Ribosomal_S25 PF03297.10 KKK21649.1 - 1.5e-27 95.6 0.6 1.5e-27 95.6 0.4 1.9 2 0 0 2 2 2 1 S25 ribosomal protein WD40 PF00400.27 KKK21649.1 - 0.0013 18.4 1.5 2 8.4 0.1 4.5 4 0 0 4 4 4 1 WD domain, G-beta repeat MarR_2 PF12802.2 KKK21649.1 - 0.07 12.8 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 MarR family Cyt-b5 PF00173.23 KKK21650.1 - 5.2e-10 38.9 0.0 7.2e-10 38.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NQR2_RnfD_RnfE PF03116.10 KKK21650.1 - 0.083 12.0 0.0 0.11 11.6 0.0 1.1 1 0 0 1 1 1 0 NQR2, RnfD, RnfE family Gtr1_RagA PF04670.7 KKK21651.1 - 8.6e-71 237.7 0.2 3e-70 235.9 0.0 1.8 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region Arf PF00025.16 KKK21651.1 - 0.00014 21.1 0.0 0.00032 19.9 0.0 1.5 1 1 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 KKK21651.1 - 0.0025 18.2 0.0 0.0081 16.6 0.0 1.9 2 0 0 2 2 2 1 Miro-like protein SRPRB PF09439.5 KKK21651.1 - 0.037 13.2 0.0 0.072 12.2 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_14 PF13173.1 KKK21651.1 - 0.076 12.9 0.0 0.22 11.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain Lactamase_B_2 PF12706.2 KKK21652.1 - 3.5e-27 95.2 0.1 8.5e-27 93.9 0.0 1.7 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.1 KKK21652.1 - 5.8e-22 76.9 0.0 1.8e-21 75.3 0.0 1.9 1 0 0 1 1 1 1 tRNase Z endonuclease bZIP_1 PF00170.16 KKK21652.1 - 1.7e-08 34.2 10.7 4.2e-08 33.0 7.4 1.7 1 0 0 1 1 1 1 bZIP transcription factor Lactamase_B PF00753.22 KKK21652.1 - 3.6e-07 30.0 0.0 9.4e-07 28.6 0.0 1.8 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily bZIP_2 PF07716.10 KKK21652.1 - 4.3e-05 23.2 10.0 4.3e-05 23.2 6.9 2.8 2 0 0 2 2 2 1 Basic region leucine zipper His_Phos_2 PF00328.17 KKK21653.1 - 1.7e-23 83.5 0.0 3.3e-23 82.5 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) ABC_tran PF00005.22 KKK21654.1 - 2.8e-40 137.8 9.0 5e-21 75.4 0.1 3.7 3 1 0 3 3 2 2 ABC transporter AAA_21 PF13304.1 KKK21654.1 - 4e-18 66.4 0.2 1.3e-08 35.1 0.0 3.4 3 0 0 3 3 3 2 AAA domain SMC_N PF02463.14 KKK21654.1 - 2.1e-09 36.9 4.7 0.014 14.6 0.0 4.3 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain ABC_tran_2 PF12848.2 KKK21654.1 - 7.6e-09 35.2 2.1 7.6e-09 35.2 1.4 2.5 2 1 1 3 3 1 1 ABC transporter AAA_17 PF13207.1 KKK21654.1 - 3.7e-07 30.9 0.4 0.027 15.2 0.0 3.5 3 1 0 3 3 3 2 AAA domain AAA_29 PF13555.1 KKK21654.1 - 1.9e-06 27.2 0.3 0.003 17.0 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain Miro PF08477.8 KKK21654.1 - 7.6e-05 23.1 0.7 0.55 10.7 0.0 2.9 3 0 0 3 3 2 2 Miro-like protein AAA_22 PF13401.1 KKK21654.1 - 8.9e-05 22.6 2.3 0.22 11.6 0.0 4.2 3 2 0 3 3 3 1 AAA domain AAA_16 PF13191.1 KKK21654.1 - 0.00016 21.6 0.6 0.87 9.5 0.2 2.8 2 1 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.18 KKK21654.1 - 0.0002 21.2 0.1 0.11 12.3 0.0 3.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_18 PF13238.1 KKK21654.1 - 0.00027 21.2 1.7 0.29 11.4 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_13 PF13166.1 KKK21654.1 - 0.0003 19.4 11.3 0.0018 16.8 1.0 2.6 3 0 0 3 3 3 2 AAA domain AAA_28 PF13521.1 KKK21654.1 - 0.00043 20.2 0.0 0.14 12.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 KKK21654.1 - 0.00082 19.5 0.4 0.83 9.8 0.0 3.2 4 0 0 4 4 2 1 ATPase family associated with various cellular activities (AAA) ArgK PF03308.11 KKK21654.1 - 0.00093 18.0 0.7 0.23 10.1 0.0 2.4 2 0 0 2 2 2 2 ArgK protein DUF258 PF03193.11 KKK21654.1 - 0.00094 18.4 0.2 1.6 7.9 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_5 PF07728.9 KKK21654.1 - 0.0015 18.2 1.0 0.3 10.8 0.0 3.5 3 1 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_23 PF13476.1 KKK21654.1 - 0.0017 18.7 14.3 0.4 10.9 8.6 3.2 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.1 KKK21654.1 - 0.002 18.0 0.3 1.5 8.7 0.0 3.4 4 0 0 4 4 3 1 AAA domain RNA_helicase PF00910.17 KKK21654.1 - 0.0028 17.8 0.1 0.87 9.7 0.0 2.5 2 0 0 2 2 2 1 RNA helicase AAA_33 PF13671.1 KKK21654.1 - 0.0031 17.3 0.2 2.6 7.9 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_25 PF13481.1 KKK21654.1 - 0.0033 16.8 0.0 0.67 9.3 0.0 2.9 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 KKK21654.1 - 0.0044 16.7 0.2 0.89 9.2 0.0 2.9 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 KKK21654.1 - 0.0093 15.6 0.2 0.49 10.0 0.0 2.5 2 0 0 2 2 2 1 NACHT domain NTPase_1 PF03266.10 KKK21654.1 - 0.023 14.4 0.8 15 5.2 0.0 3.8 4 0 0 4 4 3 0 NTPase SbcCD_C PF13558.1 KKK21654.1 - 0.12 12.3 2.8 5.7 6.9 0.0 3.6 3 1 0 3 3 3 0 Putative exonuclease SbcCD, C subunit PduV-EutP PF10662.4 KKK21654.1 - 0.13 11.7 0.6 13 5.2 0.1 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF87 PF01935.12 KKK21654.1 - 1.6 8.5 6.5 2.6 7.7 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function DUF87 FA_hydroxylase PF04116.8 KKK21655.1 - 1.5e-15 57.5 15.5 1.5e-15 57.5 10.7 2.4 2 0 0 2 2 2 2 Fatty acid hydroxylase superfamily Ferrochelatase PF00762.14 KKK21674.1 - 9.4e-93 310.6 0.0 1.1e-92 310.4 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase Ku PF02735.11 KKK21675.1 - 1.3e-34 119.4 0.0 2e-34 118.7 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.10 KKK21675.1 - 3.5e-34 118.2 0.0 4.5e-34 117.8 0.0 1.2 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.9 KKK21675.1 - 2.9e-14 53.3 1.7 9.7e-14 51.6 1.2 1.9 1 1 0 1 1 1 1 Ku70/Ku80 C-terminal arm VWA PF00092.23 KKK21675.1 - 0.0015 18.3 0.0 0.004 16.9 0.0 1.7 1 1 0 1 1 1 1 von Willebrand factor type A domain SE PF08491.5 KKK21676.1 - 5.5e-95 317.3 0.0 6.8e-95 317.0 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase DAO PF01266.19 KKK21676.1 - 6.4e-08 31.8 0.7 1.2e-05 24.4 0.6 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 KKK21676.1 - 4.4e-07 29.2 0.1 0.00038 19.6 0.4 2.2 2 0 0 2 2 2 2 FAD binding domain GIDA PF01134.17 KKK21676.1 - 0.00054 18.9 0.2 0.029 13.2 0.2 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_8 PF13450.1 KKK21676.1 - 0.00096 19.1 0.6 0.0022 17.9 0.4 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KKK21676.1 - 0.0021 18.3 0.3 0.0046 17.3 0.2 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KKK21676.1 - 0.0022 17.1 0.4 0.0089 15.1 0.0 1.9 2 0 0 2 2 2 1 Thi4 family FAD_oxidored PF12831.2 KKK21676.1 - 0.0024 17.0 0.8 0.0034 16.5 0.5 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KKK21676.1 - 0.0059 15.4 2.0 0.011 14.6 1.3 1.4 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.7 KKK21676.1 - 0.012 14.5 0.6 0.045 12.6 0.3 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein HI0933_like PF03486.9 KKK21676.1 - 0.037 12.5 0.3 0.065 11.6 0.2 1.4 1 0 0 1 1 1 0 HI0933-like protein 3HCDH_N PF02737.13 KKK21676.1 - 0.056 13.0 0.2 0.094 12.3 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.9 KKK21676.1 - 0.063 13.1 0.2 0.1 12.4 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 KKK21676.1 - 0.072 12.5 0.1 0.12 11.7 0.1 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.15 KKK21676.1 - 0.11 12.5 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase GMC_oxred_N PF00732.14 KKK21676.1 - 0.11 11.5 0.5 7 5.7 0.1 2.3 2 0 0 2 2 2 0 GMC oxidoreductase ThiF PF00899.16 KKK21676.1 - 0.24 11.2 1.4 0.44 10.3 1.0 1.4 1 0 0 1 1 1 0 ThiF family PPR_3 PF13812.1 KKK21677.1 - 3.5e-09 36.2 1.5 0.0039 17.3 0.0 6.2 7 0 0 7 7 7 2 Pentatricopeptide repeat domain PPR PF01535.15 KKK21677.1 - 8.7e-05 22.2 1.2 1.1 9.4 0.0 5.4 6 0 0 6 6 6 1 PPR repeat PPR_2 PF13041.1 KKK21677.1 - 0.00019 21.3 0.2 4.8 7.2 0.0 4.6 4 1 0 4 4 4 1 PPR repeat family RPN7 PF10602.4 KKK21677.1 - 0.047 13.0 0.1 0.098 12.0 0.1 1.5 1 0 0 1 1 1 0 26S proteasome subunit RPN7 RHSP PF07999.6 KKK21677.1 - 0.048 12.2 0.0 0.3 9.6 0.0 1.9 2 0 0 2 2 2 0 Retrotransposon hot spot protein RC-P840_PscD PF10657.4 KKK21677.1 - 0.087 12.6 0.0 1.1 9.1 0.0 2.5 2 0 0 2 2 2 0 Photosystem P840 reaction centre protein PscD TPR_11 PF13414.1 KKK21677.1 - 0.11 12.1 0.2 0.33 10.6 0.2 1.8 1 0 0 1 1 1 0 TPR repeat PH_9 PF15410.1 KKK21678.1 - 1.3e-19 70.5 0.0 8.1e-19 67.9 0.0 2.1 2 0 0 2 2 2 1 Pleckstrin homology domain Sec7 PF01369.15 KKK21678.1 - 3e-19 69.4 0.0 9.2e-11 41.7 0.2 2.5 1 1 1 2 2 2 2 Sec7 domain Zn_clus PF00172.13 KKK21679.1 - 1.2e-08 34.7 12.8 2.3e-08 33.7 8.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldose_epim PF01263.15 KKK21680.1 - 1.3e-58 198.5 0.0 1.4e-58 198.3 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase Ras PF00071.17 KKK21681.1 - 2.6e-37 127.7 0.0 3.1e-36 124.1 0.0 2.0 1 1 0 1 1 1 1 Ras family Miro PF08477.8 KKK21681.1 - 1.3e-10 41.8 0.0 3.1e-10 40.5 0.0 1.6 2 0 0 2 2 2 1 Miro-like protein MMR_HSR1 PF01926.18 KKK21681.1 - 0.0052 16.7 0.0 0.0086 16.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.16 KKK21681.1 - 0.022 13.9 0.0 0.057 12.6 0.0 1.7 1 1 1 2 2 2 0 ADP-ribosylation factor family PRK PF00485.13 KKK21681.1 - 0.14 11.6 0.0 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family QRPTase_C PF01729.14 KKK21682.1 - 1.3e-47 161.4 0.9 1e-44 152.0 0.6 2.1 1 1 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.11 KKK21682.1 - 2.9e-07 30.2 0.0 1.1e-06 28.2 0.0 2.0 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, N-terminal domain Microtub_assoc PF07989.6 KKK21683.1 - 2.6e-24 84.8 10.3 2.6e-24 84.8 7.2 7.4 7 2 1 8 8 8 1 Microtubule associated Mto2_bdg PF12808.2 KKK21683.1 - 2.1e-22 78.9 29.2 3.8e-19 68.5 8.5 11.6 11 2 1 12 12 12 2 Micro-tubular organiser Mto1 C-term Mto2-binding region Reo_sigmaC PF04582.7 KKK21683.1 - 0.0005 19.3 1.5 0.0005 19.3 1.0 5.8 5 1 1 6 6 6 4 Reovirus sigma C capsid protein TMF_TATA_bd PF12325.3 KKK21683.1 - 0.006 16.3 12.2 0.006 16.3 8.5 10.0 7 2 5 12 12 12 2 TATA element modulatory factor 1 TATA binding UNC-50 PF05216.8 KKK21684.1 - 5.7e-84 280.9 4.9 7.2e-84 280.5 3.4 1.1 1 0 0 1 1 1 1 UNC-50 family Aldo_ket_red PF00248.16 KKK21700.1 - 6.2e-62 208.9 0.0 7.1e-62 208.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Aconitase PF00330.15 KKK21701.1 - 7.8e-171 568.6 0.0 9.4e-171 568.3 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 KKK21701.1 - 5.7e-45 152.6 0.0 1.2e-44 151.5 0.0 1.6 1 0 0 1 1 1 1 Aconitase C-terminal domain WD40 PF00400.27 KKK21702.1 - 4.7e-22 76.9 11.3 2.2e-05 24.1 0.0 4.6 4 0 0 4 4 4 4 WD domain, G-beta repeat Vert_HS_TF PF06546.6 KKK21702.1 - 0.012 15.0 0.1 0.019 14.4 0.1 1.2 1 0 0 1 1 1 0 Vertebrate heat shock transcription factor Glycos_transf_4 PF00953.16 KKK21703.1 - 1.6e-30 105.9 14.2 1.6e-30 105.9 9.8 2.5 3 1 0 3 3 3 1 Glycosyl transferase family 4 AA_permease PF00324.16 KKK21704.1 - 2.8e-57 194.1 37.5 8.4e-32 110.1 12.4 1.9 2 0 0 2 2 2 2 Amino acid permease AA_permease_2 PF13520.1 KKK21704.1 - 1.2e-21 76.7 32.7 2.7e-21 75.6 22.7 1.5 1 1 0 1 1 1 1 Amino acid permease MTHFR PF02219.12 KKK21706.1 - 5.1e-98 327.6 0.0 1.3e-55 188.5 0.0 2.1 1 1 1 2 2 2 2 Methylenetetrahydrofolate reductase ATP-synt_F PF01990.12 KKK21707.1 - 3.4e-31 107.4 0.1 3.9e-31 107.2 0.0 1.1 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit DUF257 PF03192.8 KKK21707.1 - 0.042 13.1 0.0 0.051 12.8 0.0 1.1 1 0 0 1 1 1 0 Pyrococcus protein of unknown function, DUF257 DUF2418 PF10332.4 KKK21708.1 - 4.5e-35 119.9 0.1 4.5e-35 119.9 0.1 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2418) Pribosyltran PF00156.22 KKK21709.1 - 5.5e-15 55.1 0.3 9e-15 54.5 0.2 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain DUF3186 PF11382.3 KKK21709.1 - 0.02 14.0 0.1 0.027 13.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3186) Alpha-amylase PF00128.19 KKK21710.1 - 5.8e-18 65.3 1.0 5e-17 62.2 0.7 2.5 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_transf_5 PF08323.6 KKK21710.1 - 1.1e-14 54.5 0.1 1.9e-14 53.7 0.0 1.3 1 0 0 1 1 1 1 Starch synthase catalytic domain Glyco_trans_1_4 PF13692.1 KKK21710.1 - 2.3e-06 27.7 0.0 5e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.15 KKK21710.1 - 5.2e-06 25.9 0.0 1.6e-05 24.3 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 VGCC_beta4Aa_N PF12052.3 KKK21710.1 - 0.14 12.0 0.2 0.38 10.6 0.1 1.7 1 0 0 1 1 1 0 Voltage gated calcium channel subunit beta domain 4Aa N terminal HCMVantigenic_N PF12154.3 KKK21725.1 - 2.5 8.0 8.2 0.19 11.6 2.0 1.9 2 0 0 2 2 2 0 Glycoprotein B N-terminal antigenic domain of HCMV tRNA-synt_1b PF00579.20 KKK21726.1 - 9.4e-60 202.1 0.0 1.2e-59 201.9 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) RTC4 PF14474.1 KKK21726.1 - 0.12 12.3 0.0 0.38 10.6 0.0 1.9 2 0 0 2 2 2 0 RTC4-like domain Alpha-amylase PF00128.19 KKK21727.1 - 1.2e-102 343.5 0.2 2.2e-102 342.7 0.1 1.3 1 0 0 1 1 1 1 Alpha amylase, catalytic domain hDGE_amylase PF14701.1 KKK21727.1 - 0.036 12.9 0.0 0.071 12.0 0.0 1.4 1 0 0 1 1 1 0 glucanotransferase domain of human glycogen debranching enzyme Glyco_hydro_72 PF03198.9 KKK21728.1 - 5.5e-101 337.6 0.0 9.7e-101 336.8 0.0 1.4 1 1 0 1 1 1 1 Glucanosyltransferase Glyco_hydro_2_C PF02836.12 KKK21728.1 - 0.00016 20.7 0.0 0.00024 20.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Cellulase PF00150.13 KKK21728.1 - 0.0047 16.1 0.1 0.049 12.8 0.0 2.2 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) AP_endonuc_2 PF01261.19 KKK21728.1 - 0.013 14.7 0.0 0.72 9.1 0.0 2.3 2 0 0 2 2 2 0 Xylose isomerase-like TIM barrel Pkinase PF00069.20 KKK21729.1 - 1.1e-10 41.0 0.0 2.2e-07 30.3 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KKK21729.1 - 5.3e-08 32.2 0.0 2.3e-07 30.1 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 KKK21729.1 - 0.00097 18.1 0.0 0.0014 17.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Sds3 PF08598.6 KKK21730.1 - 1e-50 172.1 6.0 2.3e-49 167.7 4.1 2.1 1 1 0 1 1 1 1 Sds3-like Lectin_N PF03954.9 KKK21730.1 - 0.077 12.3 0.6 0.88 8.9 0.1 2.2 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain Mo-nitro_C PF06967.6 KKK21731.1 - 0.077 13.1 0.1 0.84 9.8 0.1 2.3 2 0 0 2 2 2 0 Mo-dependent nitrogenase C-terminus Ribonuc_L-PSP PF01042.16 KKK21732.1 - 8.6e-12 44.8 0.0 1.1e-11 44.5 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP phage_tail_N PF08400.5 KKK21735.1 - 0.049 13.3 0.1 0.082 12.6 0.1 1.4 1 0 0 1 1 1 0 Prophage tail fibre N-terminal MDFI PF15316.1 KKK21735.1 - 2.9 7.8 9.8 0.47 10.4 1.2 2.1 2 0 0 2 2 2 0 MyoD family inhibitor Abhydrolase_6 PF12697.2 KKK21736.1 - 8e-13 48.7 0.3 1.2e-12 48.1 0.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KKK21736.1 - 3.6e-10 39.8 0.0 9e-10 38.4 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KKK21736.1 - 0.00019 21.1 0.0 0.00049 19.8 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Cutinase PF01083.17 KKK21736.1 - 0.081 12.6 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Cutinase DUF3604 PF12228.3 KKK21736.1 - 0.22 9.6 0.0 0.32 9.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3604) F-box-like PF12937.2 KKK21737.1 - 0.0055 16.4 1.1 0.0055 16.4 0.8 2.3 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KKK21737.1 - 0.036 13.7 1.4 0.036 13.7 1.0 2.4 2 0 0 2 2 2 0 F-box domain Cohesin_load PF10345.4 KKK21738.1 - 2.4e-179 597.4 7.8 2.8e-179 597.2 5.4 1.0 1 0 0 1 1 1 1 Cohesin loading factor DUF947 PF06102.7 KKK21739.1 - 1.9e-50 170.9 19.2 1.9e-50 170.9 13.3 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF947) RNA_pol_L_2 PF13656.1 KKK21741.1 - 8e-31 105.3 0.0 1.1e-30 104.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 KKK21741.1 - 2.2e-13 49.0 0.0 3.2e-13 48.5 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Complex1_LYR_2 PF13233.1 KKK21742.1 - 2e-08 34.6 0.5 2.4e-08 34.3 0.4 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_1 PF13232.1 KKK21742.1 - 4.6e-05 23.5 0.5 6.8e-05 22.9 0.4 1.4 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 KKK21742.1 - 0.00017 21.2 2.7 0.00042 20.0 1.9 1.7 1 1 0 1 1 1 1 Complex 1 protein (LYR family) DNA_pol_A_exo1 PF01612.15 KKK21744.1 - 1.4e-41 141.9 0.0 2.8e-41 140.9 0.0 1.5 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.7 KKK21744.1 - 8.6e-28 96.4 0.2 8e-27 93.3 0.5 2.4 2 0 0 2 2 2 1 PMC2NT (NUC016) domain HRDC PF00570.18 KKK21744.1 - 6.8e-11 41.7 0.1 2.8e-10 39.7 0.0 2.2 2 0 0 2 2 2 1 HRDC domain DUF3628 PF12300.3 KKK21744.1 - 0.022 14.8 6.6 0.044 13.8 4.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3628) DnaJ-X PF14308.1 KKK21757.1 - 1.2e-70 237.0 4.3 3.7e-70 235.3 3.3 1.7 2 0 0 2 2 2 1 X-domain of DnaJ-containing DnaJ PF00226.26 KKK21757.1 - 3e-26 90.9 0.2 8.1e-26 89.5 0.1 1.8 1 0 0 1 1 1 1 DnaJ domain Hemerythrin PF01814.18 KKK21758.1 - 3.6e-07 30.3 0.1 1.2e-06 28.6 0.1 1.8 1 1 0 1 1 1 1 Hemerythrin HHE cation binding domain SQS_PSY PF00494.14 KKK21759.1 - 1.4e-41 142.5 0.0 3.9e-41 141.1 0.0 1.7 2 0 0 2 2 2 1 Squalene/phytoene synthase Peroxin-22 PF12827.2 KKK21759.1 - 0.11 12.2 0.1 0.27 10.9 0.0 1.6 1 0 0 1 1 1 0 Peroxisomal biogenesis protein family adh_short PF00106.20 KKK21760.1 - 2.2e-32 112.2 0.3 3.5e-32 111.6 0.0 1.4 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 KKK21760.1 - 3.1e-19 69.7 0.0 3.8e-19 69.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KKK21760.1 - 1.9e-10 40.7 0.0 2.8e-10 40.1 0.0 1.3 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 KKK21760.1 - 3.8e-06 26.5 0.0 5.3e-06 26.0 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KKK21760.1 - 7.7e-05 22.7 0.3 0.0054 16.7 0.1 2.5 2 1 0 2 2 2 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 KKK21760.1 - 0.0018 18.0 0.2 0.0032 17.2 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase RmlD_sub_bind PF04321.12 KKK21760.1 - 0.05 12.4 0.0 0.15 10.9 0.0 1.8 1 1 0 1 1 1 0 RmlD substrate binding domain ApbA PF02558.11 KKK21760.1 - 0.12 11.7 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Fungal_trans PF04082.13 KKK21761.1 - 2.4e-27 95.4 1.9 3.7e-27 94.8 1.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK21761.1 - 1.4e-06 28.1 6.7 3e-06 27.0 4.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cerato-platanin PF07249.7 KKK21762.1 - 8.9e-28 96.6 1.6 1.3e-15 57.4 0.1 2.0 1 1 1 2 2 2 2 Cerato-platanin Glyco_hydro_16 PF00722.16 KKK21763.1 - 3.1e-08 33.1 0.0 5.9e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Sugar_tr PF00083.19 KKK21764.1 - 3.8e-80 269.6 22.0 4.7e-80 269.3 15.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KKK21764.1 - 6.1e-25 87.6 31.6 1.1e-23 83.5 21.9 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 KKK21764.1 - 1.1e-07 30.4 2.2 1.7e-07 29.8 1.5 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) zf-H2C2 PF09337.5 KKK21765.1 - 2.1e-23 81.4 4.6 3.8e-23 80.6 3.2 1.4 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger Acetyltransf_1 PF00583.19 KKK21765.1 - 1.1e-06 28.5 0.0 1.9e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.1 KKK21765.1 - 0.00063 19.9 0.0 0.0012 18.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KKK21765.1 - 0.0021 17.7 0.0 0.0042 16.8 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.1 KKK21765.1 - 0.0049 16.8 0.0 0.0099 15.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain HK PF02110.10 KKK21766.1 - 9e-81 270.6 0.3 9e-81 270.6 0.2 1.8 2 1 1 3 3 3 1 Hydroxyethylthiazole kinase family TMP-TENI PF02581.12 KKK21766.1 - 8.7e-57 191.1 2.5 1.4e-56 190.4 1.7 1.3 1 0 0 1 1 1 1 Thiamine monophosphate synthase/TENI Beta-lactamase PF00144.19 KKK21767.1 - 1e-28 100.3 1.1 1.7e-28 99.6 0.8 1.2 1 0 0 1 1 1 1 Beta-lactamase Peptidase_S9 PF00326.16 KKK21768.1 - 2.2e-40 138.1 0.6 3e-40 137.7 0.4 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KKK21768.1 - 1.7e-14 53.7 1.4 3.8e-14 52.6 1.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KKK21768.1 - 1.2e-10 41.6 6.8 6.3e-10 39.3 4.7 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 KKK21768.1 - 3.5e-10 39.5 0.2 3.9e-09 36.0 0.1 2.2 1 1 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S15 PF02129.13 KKK21768.1 - 3.7e-10 39.6 2.5 1.9e-05 24.2 0.8 2.4 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) BAAT_C PF08840.6 KKK21768.1 - 6.4e-07 29.2 0.1 5.8e-06 26.1 0.0 2.1 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_4 PF08386.5 KKK21768.1 - 1.3e-05 25.0 0.1 0.00031 20.5 0.0 2.3 2 0 0 2 2 2 1 TAP-like protein Abhydrolase_3 PF07859.8 KKK21768.1 - 1.5e-05 24.6 1.5 8.3e-05 22.2 1.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold PD40 PF07676.7 KKK21768.1 - 0.00015 21.2 1.7 0.0029 17.2 0.3 2.9 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat Abhydrolase_2 PF02230.11 KKK21768.1 - 0.00026 20.5 0.1 0.016 14.6 0.0 2.8 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase DUF829 PF05705.9 KKK21768.1 - 0.0014 18.4 0.0 0.002 17.8 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Abhydrolase_1 PF00561.15 KKK21768.1 - 0.0047 16.5 0.2 0.3 10.5 0.0 2.3 1 1 1 2 2 2 1 alpha/beta hydrolase fold Esterase_phd PF10503.4 KKK21768.1 - 0.0054 16.0 1.3 0.043 13.0 0.6 2.5 2 1 0 2 2 2 1 Esterase PHB depolymerase FSH1 PF03959.8 KKK21768.1 - 0.058 12.8 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) LIP PF03583.9 KKK21768.1 - 0.13 11.4 1.9 0.52 9.4 0.0 2.1 2 0 0 2 2 2 0 Secretory lipase Beta-lactamase PF00144.19 KKK21769.1 - 3.9e-42 144.4 0.2 5.4e-42 143.9 0.1 1.1 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.3 KKK21769.1 - 1.3e-08 34.5 0.0 2.3e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) CoA_transf_3 PF02515.12 KKK21770.1 - 5.8e-30 103.9 0.2 1.8e-29 102.3 0.0 1.8 2 0 0 2 2 2 1 CoA-transferase family III CrtC PF07143.6 KKK21771.1 - 2.7e-14 53.1 0.8 3.7e-14 52.7 0.1 1.5 1 1 1 2 2 2 1 Hydroxyneurosporene synthase (CrtC) DUF605 PF04652.11 KKK21772.1 - 3.1 7.0 7.1 4.2 6.6 4.9 1.1 1 0 0 1 1 1 0 Vta1 like Aconitase PF00330.15 KKK21773.1 - 7.7e-157 522.4 0.0 3.4e-156 520.3 0.0 1.8 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 KKK21773.1 - 2.5e-39 134.3 0.0 3.9e-39 133.7 0.0 1.3 1 0 0 1 1 1 1 Aconitase C-terminal domain DUF3425 PF11905.3 KKK21774.1 - 7.9e-37 126.1 1.0 1.2e-36 125.5 0.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 KKK21774.1 - 0.75 9.8 11.2 0.096 12.6 4.9 1.6 2 0 0 2 2 2 0 bZIP transcription factor Rad4 PF03835.10 KKK21775.1 - 8.5e-34 116.0 0.2 2.9e-33 114.2 0.0 2.1 2 0 0 2 2 2 1 Rad4 transglutaminase-like domain BHD_3 PF10405.4 KKK21775.1 - 1.2e-28 98.6 0.6 3e-28 97.3 0.1 1.9 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.4 KKK21775.1 - 7.1e-23 79.8 0.0 1.3e-22 79.0 0.0 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.4 KKK21775.1 - 5.5e-15 55.4 2.2 8e-15 54.9 0.1 2.5 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.14 KKK21775.1 - 0.012 15.7 0.0 0.046 13.9 0.0 2.1 1 1 0 1 1 1 0 Transglutaminase-like superfamily FAA_hydrolase PF01557.13 KKK21776.1 - 4e-49 167.0 0.0 5.9e-49 166.4 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family DUF3712 PF12505.3 KKK21777.1 - 2e-33 115.0 0.4 3.8e-33 114.1 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3712) AgrB PF04647.10 KKK21777.1 - 0.041 12.9 0.9 0.061 12.3 0.7 1.2 1 0 0 1 1 1 0 Accessory gene regulator B Zn_clus PF00172.13 KKK21778.1 - 1.2e-09 37.9 6.3 3e-09 36.6 4.4 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 KKK21779.1 - 1.3e-14 53.6 49.4 9.1e-09 34.4 21.2 2.7 2 1 1 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.8 KKK21779.1 - 3.9e-08 31.9 23.0 8.9e-07 27.4 16.1 2.2 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) GtrA PF04138.9 KKK21779.1 - 0.0015 18.5 9.0 0.0015 18.5 6.2 4.0 4 2 0 4 4 4 1 GtrA-like protein DUF872 PF05915.7 KKK21779.1 - 0.14 11.9 0.9 0.5 10.2 0.1 2.3 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) Adeno_E3_14_5 PF04834.7 KKK21779.1 - 7.8 6.9 5.6 19 5.7 0.2 2.8 2 1 0 2 2 2 0 Early E3 14.5 kDa protein Copper-fist PF00649.13 KKK21780.1 - 4.5e-18 64.1 0.4 4.5e-18 64.1 0.3 2.2 2 0 0 2 2 2 1 Copper fist DNA binding domain HsbA PF12296.3 KKK21781.1 - 9.9e-26 90.0 10.8 9.9e-26 90.0 7.5 2.5 2 1 0 2 2 2 1 Hydrophobic surface binding protein A NPV_P10 PF05531.7 KKK21781.1 - 0.5 10.6 5.8 4.4 7.6 4.0 2.5 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein tRNA-synt_1b PF00579.20 KKK21782.1 - 7.1e-25 87.7 0.0 1.3e-24 86.8 0.0 1.4 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) tRNA_bind PF01588.15 KKK21783.1 - 1.4e-21 76.1 0.0 1.7e-19 69.4 0.0 2.6 1 1 0 1 1 1 1 Putative tRNA binding domain GST_C_3 PF14497.1 KKK21783.1 - 3.3e-10 40.3 0.0 8.9e-10 38.9 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KKK21783.1 - 1e-05 25.3 0.0 3.1e-05 23.7 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KKK21783.1 - 0.0035 17.3 0.0 0.0035 17.3 0.0 2.3 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain NPR3 PF03666.8 KKK21783.1 - 0.016 13.7 1.7 0.024 13.1 1.2 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 IDO PF01231.13 KKK21783.1 - 0.11 10.8 0.0 0.19 10.1 0.0 1.3 1 0 0 1 1 1 0 Indoleamine 2,3-dioxygenase RR_TM4-6 PF06459.7 KKK21783.1 - 6.4 6.5 11.7 9.7 5.9 8.1 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 APH PF01636.18 KKK21784.1 - 1.2e-07 31.7 0.0 1.7e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KKK21784.1 - 0.063 12.8 0.0 0.098 12.2 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pkinase PF00069.20 KKK21785.1 - 1.2e-56 191.7 0.0 1.9e-56 191.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK21785.1 - 1.9e-33 115.6 0.0 7.6e-32 110.4 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 KKK21785.1 - 2.2e-08 33.4 0.0 6.8e-08 31.8 0.0 1.7 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 KKK21785.1 - 0.0054 16.4 0.1 0.013 15.2 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family Sybindin PF04099.7 KKK21786.1 - 1.8e-25 89.2 0.0 2.5e-25 88.8 0.0 1.1 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.8 KKK21786.1 - 0.00065 19.5 0.0 0.0011 18.8 0.0 1.3 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region SET PF00856.23 KKK21787.1 - 2.6e-21 76.5 0.3 2.6e-21 76.5 0.2 4.3 5 1 0 5 5 5 1 SET domain SRI PF08236.6 KKK21787.1 - 4.8e-21 74.4 13.7 1.1e-20 73.4 9.5 1.6 1 0 0 1 1 1 1 SRI (Set2 Rpb1 interacting) domain WW PF00397.21 KKK21787.1 - 0.0087 15.9 1.4 0.023 14.5 1.0 1.8 1 0 0 1 1 1 1 WW domain COPI_C PF06957.6 KKK21787.1 - 0.053 12.0 5.4 0.096 11.1 3.8 1.4 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus DUF3287 PF11690.3 KKK21787.1 - 2 8.5 8.6 0.43 10.6 1.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3287) AT_hook PF02178.14 KKK21788.1 - 0.035 13.7 1.5 0.035 13.7 1.0 2.7 2 0 0 2 2 2 0 AT hook motif eIF-6 PF01912.13 KKK21789.1 - 1.1e-28 99.7 0.3 1.5e-28 99.2 0.1 1.3 2 0 0 2 2 2 1 eIF-6 family Brix PF04427.13 KKK21790.1 - 2.2e-34 118.8 0.0 3e-34 118.3 0.0 1.2 1 0 0 1 1 1 1 Brix domain Nop14 PF04147.7 KKK21790.1 - 0.015 13.2 17.8 0.019 12.9 12.3 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 KKK21790.1 - 0.079 10.9 13.0 0.11 10.5 9.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Sporozoite_P67 PF05642.6 KKK21790.1 - 0.25 9.1 7.2 0.34 8.7 5.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Cwf_Cwc_15 PF04889.7 KKK21790.1 - 1.6 8.3 20.1 3.5 7.2 14.0 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein NOA36 PF06524.7 KKK21790.1 - 8.6 5.5 9.5 12 4.9 6.6 1.3 1 0 0 1 1 1 0 NOA36 protein Pept_tRNA_hydro PF01195.14 KKK21791.1 - 1.2e-20 73.8 0.0 7.9e-06 25.4 0.0 3.1 2 1 1 3 3 3 3 Peptidyl-tRNA hydrolase tRNA-synt_2b PF00587.20 KKK21792.1 - 8.9e-67 223.9 0.1 1.6e-66 223.1 0.1 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 KKK21792.1 - 2.1e-19 69.2 0.2 9.8e-19 67.0 0.0 2.3 2 0 0 2 2 2 1 Anticodon binding domain BAR PF03114.13 KKK21793.1 - 7.9e-58 195.6 2.5 9.8e-58 195.3 1.8 1.1 1 0 0 1 1 1 1 BAR domain FliD_N PF02465.13 KKK21793.1 - 0.27 11.6 1.2 7.3 7.0 0.3 2.5 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Pkinase PF00069.20 KKK21794.1 - 1.6e-63 214.3 0.0 3.9e-63 213.0 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK21794.1 - 1.7e-26 92.8 0.0 2.4e-26 92.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KKK21794.1 - 0.0037 16.2 0.0 0.0076 15.2 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KKK21794.1 - 0.0039 16.2 0.0 0.0074 15.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KKK21794.1 - 0.077 12.7 0.3 1.5 8.5 0.0 2.6 2 1 1 3 3 3 0 Phosphotransferase enzyme family NAD_kinase PF01513.16 KKK21798.1 - 2.3e-60 203.8 0.0 7.1e-60 202.2 0.0 1.7 1 1 0 1 1 1 1 ATP-NAD kinase RNase_PH PF01138.16 KKK21799.1 - 0.02 15.2 0.1 0.049 13.9 0.1 1.7 1 1 0 1 1 1 0 3' exoribonuclease family, domain 1 E1-E2_ATPase PF00122.15 KKK21800.1 - 5.9e-61 205.4 6.7 1.3e-60 204.3 4.6 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KKK21800.1 - 2.1e-33 115.3 1.2 2.1e-33 115.3 0.8 2.4 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KKK21800.1 - 3.4e-27 96.2 0.3 7.9e-26 91.8 0.2 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KKK21800.1 - 9.1e-15 53.8 0.0 9.1e-15 53.8 0.0 1.9 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 KKK21800.1 - 3.2e-14 52.6 0.0 6.1e-14 51.7 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 KKK21800.1 - 3.1e-13 50.3 0.1 8.7e-13 48.8 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KKK21800.1 - 2.9e-07 30.3 2.4 1e-05 25.2 0.6 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DEAD PF00270.24 KKK21801.1 - 4.4e-33 114.1 0.5 7.2e-32 110.1 0.1 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KKK21801.1 - 1.9e-21 75.6 0.5 3.4e-21 74.8 0.4 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 KKK21801.1 - 0.0077 15.9 0.7 0.065 12.9 0.1 2.6 2 1 1 3 3 3 1 Part of AAA domain AAA_30 PF13604.1 KKK21801.1 - 0.04 13.4 0.1 0.11 12.0 0.0 1.7 2 0 0 2 2 2 0 AAA domain SH3_9 PF14604.1 KKK21802.1 - 4.3e-25 87.0 0.2 1.5e-12 46.8 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain FCH PF00611.18 KKK21802.1 - 5.1e-21 74.6 0.1 2.3e-20 72.5 0.0 2.2 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.23 KKK21802.1 - 1.8e-18 65.6 0.1 1.3e-08 34.0 0.0 2.4 2 0 0 2 2 2 2 SH3 domain C1_1 PF00130.17 KKK21802.1 - 7.6e-15 54.3 5.3 1.5e-14 53.4 3.6 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SH3_2 PF07653.12 KKK21802.1 - 0.00079 18.8 0.0 0.036 13.5 0.0 2.4 2 0 0 2 2 2 1 Variant SH3 domain SH3_3 PF08239.6 KKK21802.1 - 0.00093 19.3 0.1 0.023 14.8 0.0 2.4 2 0 0 2 2 2 1 Bacterial SH3 domain Ax_dynein_light PF10211.4 KKK21802.1 - 0.013 15.3 3.4 0.013 15.3 2.3 2.8 3 0 0 3 3 3 0 Axonemal dynein light chain C1_2 PF03107.11 KKK21802.1 - 0.028 14.5 8.3 0.05 13.7 5.8 1.4 1 0 0 1 1 1 0 C1 domain Neur_chan_memb PF02932.11 KKK21802.1 - 1.6 8.5 5.2 1.2 9.0 0.6 2.1 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region YlqD PF11068.3 KKK21802.1 - 4.9 7.1 11.5 3.8 7.5 1.0 3.3 3 0 0 3 3 3 0 YlqD protein DUF2014 PF09427.5 KKK21803.1 - 4.6e-105 350.4 0.0 7.5e-105 349.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF2014) HLH PF00010.21 KKK21803.1 - 1.3e-18 66.4 0.1 3.4e-18 65.0 0.1 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain bZIP_1 PF00170.16 KKK21803.1 - 0.01 15.7 3.9 0.012 15.5 1.0 2.2 2 0 0 2 2 2 0 bZIP transcription factor GTP_CH_N PF12471.3 KKK21804.1 - 5.2e-90 300.3 0.0 8e-90 299.7 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal DHDPS PF00701.17 KKK21804.1 - 1.4e-38 132.2 0.0 2.3e-38 131.4 0.0 1.3 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family GTP_cyclohydro2 PF00925.15 KKK21804.1 - 9e-18 64.0 0.0 1.5e-17 63.3 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase II FSH1 PF03959.8 KKK21805.1 - 1.5e-30 106.2 0.0 7.4e-30 103.9 0.0 2.1 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 KKK21805.1 - 0.00023 21.1 0.2 0.00051 19.9 0.1 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ferric_reduct PF01794.14 KKK21806.1 - 2.7e-16 59.7 12.8 2.7e-16 59.7 8.9 1.9 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 KKK21806.1 - 3.4e-16 59.5 0.0 1.3e-15 57.6 0.0 1.9 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 KKK21806.1 - 1e-14 54.2 0.0 1.1e-13 50.9 0.0 2.4 1 1 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.16 KKK21806.1 - 0.014 15.9 0.1 0.95 10.0 0.0 2.4 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain NAD_binding_10 PF13460.1 KKK21808.1 - 1.9e-10 41.0 0.0 1.2e-09 38.4 0.0 2.0 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 KKK21808.1 - 2.8e-06 26.7 0.0 1e-05 24.9 0.0 1.9 2 0 0 2 2 2 1 NmrA-like family Semialdhyde_dh PF01118.19 KKK21808.1 - 0.0051 17.1 0.0 0.0082 16.4 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.7 KKK21808.1 - 0.01 14.7 0.0 0.017 14.0 0.0 1.3 1 0 0 1 1 1 0 Male sterility protein Epimerase PF01370.16 KKK21808.1 - 0.07 12.5 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Methyltransf_2 PF00891.13 KKK21809.1 - 4.4e-30 104.6 0.0 9.7e-30 103.5 0.0 1.6 1 0 0 1 1 1 1 O-methyltransferase NAD_binding_10 PF13460.1 KKK21809.1 - 1.4e-16 60.9 0.1 2.3e-16 60.3 0.1 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KKK21809.1 - 4.9e-07 29.4 0.0 8.3e-07 28.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 KKK21809.1 - 1e-06 28.1 0.1 2e-06 27.2 0.1 1.4 1 0 0 1 1 1 1 NmrA-like family Methyltransf_23 PF13489.1 KKK21809.1 - 0.00045 19.9 0.0 0.0011 18.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain 3Beta_HSD PF01073.14 KKK21809.1 - 0.00048 18.9 0.0 0.0007 18.3 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 KKK21809.1 - 0.0087 16.3 0.0 0.018 15.3 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Dimerisation PF08100.6 KKK21809.1 - 0.012 15.4 0.0 0.034 13.9 0.0 1.8 1 0 0 1 1 1 0 Dimerisation domain DUF4243 PF14027.1 KKK21810.1 - 2.5e-92 309.8 0.0 3e-92 309.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) DUF433 PF04255.9 KKK21810.1 - 0.077 12.4 0.0 0.19 11.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF433) DUF1772 PF08592.6 KKK21811.1 - 1.8e-23 82.7 3.7 2.2e-23 82.5 2.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) Sulfate_transp PF00916.15 KKK21811.1 - 0.017 14.1 1.8 0.018 14.0 1.3 1.1 1 0 0 1 1 1 0 Sulfate transporter family Gemini_AC4_5_2 PF08464.5 KKK21811.1 - 0.078 12.7 0.0 0.19 11.4 0.0 1.7 1 0 0 1 1 1 0 Geminivirus AC4/5 conserved region DUF1049 PF06305.6 KKK21811.1 - 0.082 12.3 1.4 4.8 6.7 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) GMC_oxred_N PF00732.14 KKK21812.1 - 2.4e-52 177.9 0.0 3.1e-52 177.5 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KKK21812.1 - 3.7e-35 121.3 0.0 6e-35 120.6 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 KKK21812.1 - 1.4e-08 34.0 0.0 5.6e-06 25.4 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KKK21812.1 - 4.2e-07 29.1 1.6 6.3e-05 22.0 0.9 2.1 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_3 PF13738.1 KKK21812.1 - 6.9e-05 23.0 0.0 0.0079 16.2 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KKK21812.1 - 0.00015 21.7 0.1 0.00038 20.4 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KKK21812.1 - 0.002 17.2 0.1 0.43 9.6 0.0 2.2 2 0 0 2 2 2 2 Thi4 family Lycopene_cycl PF05834.7 KKK21812.1 - 0.0026 16.7 0.2 0.0044 15.9 0.2 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 KKK21812.1 - 0.0056 16.5 0.0 0.011 15.6 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KKK21812.1 - 0.026 13.5 0.2 0.049 12.6 0.2 1.4 1 0 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.1 KKK21812.1 - 0.029 14.1 0.0 0.054 13.2 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding Trp_halogenase PF04820.9 KKK21812.1 - 0.035 12.7 0.0 0.051 12.1 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox PF00070.22 KKK21812.1 - 0.063 13.6 2.1 0.84 10.0 0.4 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 KKK21812.1 - 0.19 11.7 0.4 0.44 10.5 0.1 1.7 2 0 0 2 2 2 0 TrkA-N domain p450 PF00067.17 KKK21813.1 - 9.8e-63 212.2 0.0 1.3e-62 211.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Dabb PF07876.7 KKK21815.1 - 0.00011 22.5 0.3 0.12 12.7 0.1 2.2 1 1 1 2 2 2 2 Stress responsive A/B Barrel Domain adh_short PF00106.20 KKK21816.1 - 4e-12 46.3 0.5 2.1e-06 27.7 0.1 2.5 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 KKK21816.1 - 0.059 13.0 2.7 1.3 8.6 0.7 3.1 2 1 0 2 2 2 0 KR domain Eno-Rase_NADH_b PF12242.3 KKK21816.1 - 0.32 10.8 2.3 1 9.1 1.3 2.0 1 1 1 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase p450 PF00067.17 KKK21817.1 - 1.1e-62 212.0 0.0 1.4e-62 211.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Acyl_transf_1 PF00698.16 KKK21818.1 - 1e-81 274.7 0.9 8.4e-77 258.6 0.0 3.2 2 1 1 3 3 3 3 Acyl transferase domain DUF1729 PF08354.5 KKK21818.1 - 4.6e-29 99.9 0.0 2e-28 97.9 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1729) MaoC_dehydratas PF01575.14 KKK21818.1 - 2.9e-27 94.4 0.0 6.6e-27 93.3 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.1 KKK21818.1 - 1.1e-10 41.4 0.1 1.1e-09 38.1 0.0 2.3 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase ketoacyl-synt PF00109.21 KKK21819.1 - 3.4e-25 88.9 0.2 8.3e-25 87.7 0.2 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 KKK21819.1 - 9.9e-13 47.9 0.0 2.8e-12 46.5 0.0 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ACPS PF01648.15 KKK21819.1 - 6.9e-12 45.2 0.0 2e-11 43.6 0.0 1.8 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily adh_short_C2 PF13561.1 KKK21819.1 - 2e-09 37.5 0.0 7.2e-07 29.2 0.0 2.5 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KKK21819.1 - 0.00017 21.5 2.2 0.00021 21.2 0.1 2.4 2 0 0 2 2 2 1 short chain dehydrogenase Abhydrolase_3 PF07859.8 KKK21820.1 - 9e-47 159.3 0.1 1.1e-46 159.0 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.15 KKK21820.1 - 1.3e-05 25.4 0.0 1.8e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_5 PF12695.2 KKK21820.1 - 6.1e-05 22.8 0.0 7.9e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KKK21820.1 - 0.00075 19.4 0.6 0.0016 18.3 0.4 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF2424 PF10340.4 KKK21820.1 - 0.0013 17.4 0.0 0.0018 16.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_1 PF00561.15 KKK21820.1 - 0.12 11.8 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold AflR PF08493.5 KKK21821.1 - 2.8e-81 272.5 0.3 3.5e-81 272.2 0.2 1.1 1 0 0 1 1 1 1 Aflatoxin regulatory protein Ofd1_CTDD PF10637.4 KKK21825.1 - 3.1e-106 354.3 0.0 1.4e-99 332.5 0.0 2.2 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_3 PF13640.1 KKK21825.1 - 2.9e-16 59.8 0.0 6.6e-16 58.6 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 KKK21825.1 - 0.037 13.6 1.1 0.35 10.5 0.0 3.0 2 2 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily HLH PF00010.21 KKK21826.1 - 2.5e-16 59.1 1.6 4.8e-16 58.1 0.6 1.9 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain E1-E2_ATPase PF00122.15 KKK21839.1 - 1e-68 230.7 2.3 1e-68 230.7 1.6 2.6 3 1 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.21 KKK21839.1 - 8e-24 85.2 1.9 3.2e-23 83.2 0.0 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KKK21839.1 - 7.8e-13 49.0 0.0 2.8e-12 47.2 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KKK21839.1 - 1e-09 37.7 0.0 2.5e-09 36.4 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 KKK21839.1 - 0.0016 18.0 0.1 0.0034 16.9 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KKK21839.1 - 0.0094 15.8 0.0 0.022 14.7 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit DMA PF03474.9 KKK21839.1 - 0.085 12.7 0.1 2.6 7.9 0.0 2.5 2 0 0 2 2 2 0 DMRTA motif zf-H2C2_2 PF13465.1 KKK21840.1 - 5.5e-11 42.1 7.4 6e-05 23.1 0.1 3.1 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.21 KKK21840.1 - 4.2e-05 23.6 24.7 0.0058 16.8 4.6 4.2 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KKK21840.1 - 0.0056 16.9 17.5 1.3 9.4 2.9 3.9 3 0 0 3 3 3 3 C2H2-type zinc finger Bunya_G2 PF03563.8 KKK21840.1 - 0.044 12.6 3.4 0.071 11.9 2.4 1.2 1 0 0 1 1 1 0 Bunyavirus glycoprotein G2 zf-C2H2_6 PF13912.1 KKK21840.1 - 0.77 9.7 7.5 1.7 8.6 0.3 3.0 2 0 0 2 2 2 0 C2H2-type zinc finger Ribonuclease_T2 PF00445.13 KKK21841.1 - 3.9e-48 163.5 1.0 7.3e-48 162.6 0.7 1.4 1 0 0 1 1 1 1 Ribonuclease T2 family DUF155 PF02582.9 KKK21842.1 - 1.1e-43 149.1 0.0 1.5e-43 148.7 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Clathrin PF00637.15 KKK21843.1 - 2.7e-21 75.6 0.3 1.5e-18 66.7 0.1 3.2 2 1 0 2 2 2 1 Region in Clathrin and VPS WD40 PF00400.27 KKK21843.1 - 5.3e-06 26.1 0.9 0.0072 16.1 0.2 3.6 3 1 0 3 3 3 2 WD domain, G-beta repeat PQQ_3 PF13570.1 KKK21843.1 - 0.01 16.0 0.3 0.19 12.0 0.0 2.8 2 0 0 2 2 2 0 PQQ-like domain Vps39_1 PF10366.4 KKK21843.1 - 0.016 15.2 0.1 0.045 13.7 0.0 1.7 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 1 zf-RING_5 PF14634.1 KKK21843.1 - 0.048 13.3 0.8 0.1 12.3 0.5 1.5 1 0 0 1 1 1 0 zinc-RING finger domain TPR_2 PF07719.12 KKK21843.1 - 0.061 13.2 0.1 2 8.5 0.4 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.1 KKK21843.1 - 0.14 12.0 0.7 8.4 6.4 0.1 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat zf-RING_2 PF13639.1 KKK21843.1 - 0.15 11.8 1.3 0.32 10.8 0.9 1.6 1 0 0 1 1 1 0 Ring finger domain CP2 PF04516.10 KKK21844.1 - 1e-91 306.2 0.0 1.7e-91 305.5 0.0 1.3 1 0 0 1 1 1 1 CP2 transcription factor APH PF01636.18 KKK21845.1 - 0.0001 22.1 0.1 0.00033 20.4 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KKK21845.1 - 0.045 13.3 0.0 0.1 12.1 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pectinesterase PF01095.14 KKK21846.1 - 1.7e-25 89.2 0.8 2.5e-20 72.2 0.2 2.1 2 0 0 2 2 2 2 Pectinesterase TFIIS_M PF07500.9 KKK21847.1 - 8e-27 93.5 1.4 3.5e-26 91.5 0.0 2.3 2 1 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.13 KKK21847.1 - 1e-18 66.6 5.9 1.7e-18 65.9 4.1 1.4 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.6 KKK21847.1 - 5.1e-14 51.5 0.3 1e-13 50.5 0.2 1.5 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Baculo_LEF5_C PF11792.3 KKK21847.1 - 0.011 15.1 1.5 0.029 13.7 1.0 1.8 1 1 0 1 1 1 0 Baculoviridae late expression factor 5 C-terminal domain RGS PF00615.14 KKK21847.1 - 0.11 12.5 0.3 0.4 10.8 0.0 2.0 2 0 0 2 2 2 0 Regulator of G protein signaling domain LRR_6 PF13516.1 KKK21848.1 - 3e-11 42.1 2.4 0.15 12.2 0.0 7.6 8 0 0 8 8 8 3 Leucine Rich repeat LRR_4 PF12799.2 KKK21848.1 - 3.8e-08 32.7 5.0 0.021 14.4 0.0 5.4 4 2 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KKK21848.1 - 0.00053 19.6 4.4 16 6.0 0.0 6.3 7 1 0 7 7 7 0 Leucine Rich Repeat LRR_7 PF13504.1 KKK21848.1 - 0.023 14.8 1.2 2.5e+02 2.6 0.0 5.5 5 0 0 5 5 5 0 Leucine rich repeat Mpp10 PF04006.7 KKK21848.1 - 0.039 12.3 26.5 0.053 11.8 18.4 1.1 1 0 0 1 1 1 0 Mpp10 protein LRR_8 PF13855.1 KKK21848.1 - 0.041 13.6 4.9 1.8 8.4 0.0 4.5 5 1 0 5 5 5 0 Leucine rich repeat Nop14 PF04147.7 KKK21848.1 - 1.4 6.7 25.2 1.9 6.2 17.5 1.2 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 KKK21848.1 - 1.8 6.9 24.4 2.5 6.4 16.9 1.1 1 0 0 1 1 1 0 Daxx Family VID27 PF08553.5 KKK21848.1 - 6.1 4.9 16.7 8.2 4.5 11.6 1.2 1 0 0 1 1 1 0 VID27 cytoplasmic protein GOLD_2 PF13897.1 KKK21848.1 - 8.2 6.6 7.9 18 5.5 5.5 1.5 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking RRM_1 PF00076.17 KKK21849.1 - 1.1e-43 146.7 0.0 5.3e-21 74.0 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KKK21849.1 - 3.2e-33 113.5 0.0 2.8e-15 56.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KKK21849.1 - 1.3e-17 63.3 0.0 2e-07 30.7 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KKK21849.1 - 0.025 14.3 0.0 5.8 6.7 0.0 2.5 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Alg6_Alg8 PF03155.10 KKK21850.1 - 4.6e-133 444.4 15.8 7.9e-86 288.7 5.6 2.0 2 0 0 2 2 2 2 ALG6, ALG8 glycosyltransferase family O-FucT PF10250.4 KKK21851.1 - 0.046 12.8 0.0 0.046 12.8 0.0 1.2 1 0 0 1 1 1 0 GDP-fucose protein O-fucosyltransferase Proteasome PF00227.21 KKK21852.1 - 7.4e-50 168.8 0.1 1e-49 168.4 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 KKK21852.1 - 5.6e-13 47.9 0.3 9e-13 47.2 0.2 1.3 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DUF3650 PF12368.3 KKK21852.1 - 0.31 10.5 3.6 0.17 11.4 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3650) Spc97_Spc98 PF04130.8 KKK21853.1 - 7e-114 381.0 0.0 7e-114 381.0 0.0 3.4 4 0 0 4 4 4 2 Spc97 / Spc98 family DUF2373 PF10180.4 KKK21853.1 - 2.6e-20 71.7 0.1 5.4e-20 70.6 0.1 1.6 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) Herpes_pp38 PF04846.8 KKK21854.1 - 0.08 12.2 0.4 0.14 11.4 0.3 1.3 1 0 0 1 1 1 0 Herpesvirus pp38 phosphoprotein ubiquitin PF00240.18 KKK21855.1 - 1.6e-34 117.0 0.9 2.8e-34 116.3 0.6 1.4 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_S27 PF01599.14 KKK21855.1 - 2.3e-28 97.7 1.4 4.9e-28 96.7 1.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S27a Rad60-SLD PF11976.3 KKK21855.1 - 5.8e-20 70.7 0.7 1e-19 69.9 0.5 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 KKK21855.1 - 8.8e-06 25.8 0.2 4e-05 23.7 0.1 2.0 1 1 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 KKK21855.1 - 0.00011 21.9 0.0 0.00017 21.2 0.0 1.3 1 0 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 KKK21855.1 - 0.0011 18.8 0.5 0.0024 17.7 0.3 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 KKK21855.1 - 0.004 17.3 0.5 0.0055 16.8 0.3 1.2 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain IBR PF01485.16 KKK21855.1 - 0.0073 16.1 0.5 0.011 15.5 0.3 1.3 1 0 0 1 1 1 1 IBR domain DUF2870 PF11069.3 KKK21855.1 - 0.073 13.1 0.6 0.15 12.1 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2870) Plexin_cytopl PF08337.7 KKK21855.1 - 0.12 10.6 1.9 4 5.6 0.1 2.1 1 1 1 2 2 2 0 Plexin cytoplasmic RasGAP domain DUF971 PF06155.7 KKK21855.1 - 0.13 12.7 0.0 0.21 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF971) Glyco_hydro_18 PF00704.23 KKK21856.1 - 4.2e-79 266.4 4.6 1e-77 261.9 3.2 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 COX17 PF05051.8 KKK21857.1 - 5.9e-22 77.4 6.3 7.6e-22 77.0 4.3 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) Cmc1 PF08583.5 KKK21857.1 - 0.074 12.8 2.8 0.2 11.4 0.1 2.0 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like NDUFB10 PF10249.4 KKK21857.1 - 0.097 12.8 0.8 0.11 12.6 0.6 1.1 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase subunit 10 YedD PF13987.1 KKK21857.1 - 0.11 12.1 0.2 0.11 12.1 0.2 1.4 2 0 0 2 2 2 0 YedD-like protein Pet191_N PF10203.4 KKK21857.1 - 0.41 10.7 5.4 0.55 10.3 3.7 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 zf-C2H2 PF00096.21 KKK21892.1 - 2e-20 71.8 25.2 2.6e-05 24.3 1.2 4.6 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KKK21892.1 - 1.1e-19 69.6 26.3 2.9e-07 30.4 0.9 5.4 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2_4 PF13894.1 KKK21892.1 - 1.8e-13 49.7 24.4 0.00047 20.3 3.1 4.5 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KKK21892.1 - 4.1e-05 23.5 5.2 2 8.6 0.0 4.4 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KKK21892.1 - 0.007 16.5 13.0 0.51 10.6 0.0 4.1 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 KKK21892.1 - 0.012 15.5 17.2 1.6 8.7 0.9 4.4 4 0 0 4 4 4 0 C2H2-type zinc finger XPA_N PF01286.13 KKK21892.1 - 0.087 12.5 0.3 0.087 12.5 0.2 2.9 4 0 0 4 4 4 0 XPA protein N-terminal Zn-ribbon_8 PF09723.5 KKK21892.1 - 0.41 10.6 9.7 30 4.6 0.9 3.8 3 1 1 4 4 4 0 Zinc ribbon domain C1_1 PF00130.17 KKK21892.1 - 1.8 8.3 6.4 0.92 9.2 0.8 2.3 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Fer4_18 PF13746.1 KKK21892.1 - 2.1 8.8 5.4 5.1 7.5 0.2 2.6 3 0 0 3 3 2 0 4Fe-4S dicluster domain HNH PF01844.18 KKK21892.1 - 9.5 6.1 7.1 21 5.0 0.1 3.5 4 0 0 4 4 4 0 HNH endonuclease RRM_1 PF00076.17 KKK21893.1 - 3.7e-17 61.6 0.0 5.6e-17 61.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KKK21893.1 - 4.7e-11 42.5 0.0 6.9e-11 41.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KKK21893.1 - 3.6e-09 36.3 0.0 7.1e-09 35.3 0.0 1.5 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 KKK21893.1 - 0.058 13.1 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Limkain b1 B12D PF06522.6 KKK21894.1 - 4.4e-07 29.4 0.0 7.1e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit WD40 PF00400.27 KKK21895.1 - 3.3e-17 61.6 12.1 0.00023 20.9 0.0 7.1 6 1 1 7 7 7 5 WD domain, G-beta repeat SRA1 PF07304.6 KKK21895.1 - 5.7e-13 48.8 0.0 5.7e-13 48.8 0.0 3.0 3 0 0 3 3 3 1 Steroid receptor RNA activator (SRA1) Apc4_WD40 PF12894.2 KKK21895.1 - 0.0054 16.2 0.2 1.8 8.1 0.0 4.4 6 0 0 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain Sec16_C PF12931.2 KKK21895.1 - 0.014 15.1 0.1 0.08 12.6 0.1 2.1 1 1 0 1 1 1 0 Sec23-binding domain of Sec16 COX6B PF02297.12 KKK21896.1 - 7.6e-19 67.5 6.8 8.8e-19 67.2 4.7 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb APOBEC_C PF05240.9 KKK21896.1 - 0.0056 16.0 0.9 0.01 15.2 0.6 1.5 1 0 0 1 1 1 1 APOBEC-like C-terminal domain UCR_hinge PF02320.11 KKK21896.1 - 0.041 13.8 0.2 0.074 13.0 0.1 1.4 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase hinge protein UPF0203 PF05254.7 KKK21896.1 - 0.63 9.9 4.0 0.36 10.6 1.2 1.7 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0203) DUF2611 PF11022.3 KKK21901.1 - 1.5e-27 95.4 0.1 1.8e-27 95.2 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2611) COesterase PF00135.23 KKK21902.1 - 1.2e-89 301.4 0.0 3.3e-89 300.0 0.0 1.5 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KKK21902.1 - 0.00014 21.5 0.4 0.0021 17.6 0.2 2.6 1 1 1 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KKK21902.1 - 0.0019 17.4 0.1 0.0033 16.6 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family AAA PF00004.24 KKK21904.1 - 2.2e-38 131.4 0.0 8.4e-38 129.5 0.0 2.0 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 KKK21904.1 - 4.1e-06 26.7 0.0 9.2e-06 25.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KKK21904.1 - 2.1e-05 25.3 0.0 9.1e-05 23.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 KKK21904.1 - 2.5e-05 24.4 0.1 0.00055 20.0 0.1 2.5 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KKK21904.1 - 3.2e-05 23.9 0.2 0.00073 19.5 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.7 KKK21904.1 - 4e-05 22.7 0.0 6.8e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 KKK21904.1 - 4.3e-05 23.2 0.1 0.00042 20.0 0.1 2.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 KKK21904.1 - 0.00014 21.8 0.0 0.0003 20.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.12 KKK21904.1 - 0.00017 21.0 0.0 0.00037 19.9 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.1 KKK21904.1 - 0.00028 20.7 0.0 0.00056 19.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 KKK21904.1 - 0.00037 19.9 0.2 0.028 13.8 0.1 2.3 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 KKK21904.1 - 0.00086 18.5 0.1 0.0017 17.5 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Sigma54_activ_2 PF14532.1 KKK21904.1 - 0.00092 19.2 0.0 0.0032 17.5 0.0 1.9 2 0 0 2 2 2 1 Sigma-54 interaction domain RNA_helicase PF00910.17 KKK21904.1 - 0.0012 18.9 0.0 0.0033 17.5 0.0 1.9 1 1 0 1 1 1 1 RNA helicase NACHT PF05729.7 KKK21904.1 - 0.0033 17.0 0.0 0.01 15.4 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_28 PF13521.1 KKK21904.1 - 0.0037 17.2 0.0 0.0072 16.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KKK21904.1 - 0.0054 15.8 0.0 0.012 14.7 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.1 KKK21904.1 - 0.0057 16.9 0.0 0.017 15.4 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_19 PF13245.1 KKK21904.1 - 0.0062 16.2 0.2 0.028 14.1 0.0 2.0 2 0 0 2 2 2 1 Part of AAA domain AAA_24 PF13479.1 KKK21904.1 - 0.0063 16.1 0.0 0.01 15.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain Parvo_NS1 PF01057.12 KKK21904.1 - 0.018 13.9 0.0 0.029 13.2 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 ABC_tran PF00005.22 KKK21904.1 - 0.026 14.8 0.0 0.069 13.4 0.0 1.8 1 1 0 1 1 1 0 ABC transporter Sigma54_activat PF00158.21 KKK21904.1 - 0.029 13.8 0.0 0.063 12.7 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain DUF815 PF05673.8 KKK21904.1 - 0.048 12.5 0.0 0.1 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) CPT PF07931.7 KKK21904.1 - 0.058 13.0 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Arch_ATPase PF01637.13 KKK21904.1 - 0.078 12.6 0.0 0.24 11.0 0.0 1.7 1 1 1 2 2 2 0 Archaeal ATPase Rad17 PF03215.10 KKK21904.1 - 0.09 11.4 0.0 0.13 10.9 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein NB-ARC PF00931.17 KKK21904.1 - 0.097 11.5 0.0 0.22 10.3 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain Viral_helicase1 PF01443.13 KKK21904.1 - 0.11 12.0 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase UPF0079 PF02367.12 KKK21904.1 - 0.11 12.1 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 SKI PF01202.17 KKK21904.1 - 0.11 12.3 0.0 0.25 11.1 0.0 1.6 1 0 0 1 1 1 0 Shikimate kinase TIP49 PF06068.8 KKK21904.1 - 0.12 11.0 0.1 0.28 9.8 0.0 1.6 2 0 0 2 2 2 0 TIP49 C-terminus Guanylate_kin PF00625.16 KKK21904.1 - 0.14 11.5 0.0 0.84 9.0 0.0 2.3 2 1 0 2 2 2 0 Guanylate kinase ACPS PF01648.15 KKK21905.1 - 5.4e-16 58.4 0.0 1e-15 57.5 0.0 1.5 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily PHP PF02811.14 KKK21905.1 - 3.9e-09 36.5 0.0 7e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 PHP domain PigN PF04987.9 KKK21906.1 - 1.8e-169 564.0 34.7 4.1e-88 295.9 8.0 2.2 2 0 0 2 2 2 2 Phosphatidylinositolglycan class N (PIG-N) Csm1 PF12539.3 KKK21906.1 - 8.1e-28 96.7 1.2 1.4e-27 96.0 0.1 1.9 2 0 0 2 2 2 1 Chromosome segregation protein Csm1/Pcs1 Phosphodiest PF01663.17 KKK21906.1 - 4.8e-10 39.3 0.3 5.2e-08 32.5 0.0 2.4 1 1 1 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 KKK21906.1 - 1.8e-08 33.9 0.0 3.1e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 Sulfatase DUF2968 PF11180.3 KKK21906.1 - 0.018 14.4 10.1 0.036 13.4 7.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) Reo_sigmaC PF04582.7 KKK21906.1 - 0.13 11.4 2.3 0.22 10.6 1.6 1.4 1 0 0 1 1 1 0 Reovirus sigma C capsid protein HAUS-augmin3 PF14932.1 KKK21906.1 - 0.13 11.4 9.3 0.2 10.7 6.5 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 APG6 PF04111.7 KKK21906.1 - 0.39 9.6 9.6 0.65 8.9 6.7 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 AAA_13 PF13166.1 KKK21906.1 - 0.42 9.0 6.2 0.7 8.2 4.3 1.3 1 0 0 1 1 1 0 AAA domain DUF3584 PF12128.3 KKK21906.1 - 0.43 7.8 11.5 0.61 7.3 8.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Syntaxin_2 PF14523.1 KKK21906.1 - 0.44 10.6 5.5 1 9.4 3.8 1.6 1 0 0 1 1 1 0 Syntaxin-like protein Spc7 PF08317.6 KKK21906.1 - 0.44 9.1 9.3 0.72 8.4 6.4 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein NYD-SP28 PF14772.1 KKK21906.1 - 0.57 10.3 4.4 0.11 12.5 0.1 1.9 2 0 0 2 2 2 0 Sperm tail DUF3138 PF11336.3 KKK21906.1 - 1.6 6.8 6.5 2.5 6.1 4.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) ADIP PF11559.3 KKK21906.1 - 5.5 6.8 14.1 27 4.6 9.9 1.9 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF4618 PF15397.1 KKK21906.1 - 5.8 6.1 8.9 9.2 5.5 6.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) TMF_DNA_bd PF12329.3 KKK21906.1 - 7 6.5 13.8 0.96 9.2 3.9 2.9 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding Fungal_trans PF04082.13 KKK21907.1 - 3.7e-33 114.4 0.0 2.5e-32 111.7 0.0 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK21907.1 - 0.0013 18.5 1.0 0.0027 17.5 0.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cys_Met_Meta_PP PF01053.15 KKK21908.1 - 3.4e-142 473.2 0.0 4e-142 473.0 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 KKK21908.1 - 3.3e-05 22.8 0.0 6.2e-05 21.9 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V SelA PF03841.8 KKK21908.1 - 7.2e-05 21.6 0.0 0.00026 19.8 0.0 1.8 1 1 0 1 1 1 1 L-seryl-tRNA selenium transferase Aminotran_1_2 PF00155.16 KKK21908.1 - 0.00011 21.2 0.0 0.00017 20.6 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Met_gamma_lyase PF06838.6 KKK21908.1 - 0.00038 18.8 0.0 0.0022 16.3 0.0 1.9 1 1 0 1 1 1 1 Methionine gamma-lyase DegT_DnrJ_EryC1 PF01041.12 KKK21908.1 - 0.00073 18.6 0.0 0.0022 17.0 0.0 1.7 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.16 KKK21908.1 - 0.0012 18.0 0.0 0.0046 16.1 0.0 1.7 2 0 0 2 2 2 1 Beta-eliminating lyase GDC-P PF02347.11 KKK21908.1 - 0.017 13.7 0.0 0.028 13.1 0.0 1.3 1 0 0 1 1 1 0 Glycine cleavage system P-protein SR-25 PF10500.4 KKK21909.1 - 2.6 7.4 12.6 3.9 6.8 8.7 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Enolase_C PF00113.17 KKK21958.1 - 7.5e-153 507.7 0.1 9.7e-153 507.3 0.0 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 KKK21958.1 - 3.6e-56 188.7 0.1 6.4e-56 187.9 0.1 1.4 1 0 0 1 1 1 1 Enolase, N-terminal domain MAAL_C PF07476.6 KKK21958.1 - 0.028 13.3 0.1 0.75 8.6 0.0 2.4 3 0 0 3 3 3 0 Methylaspartate ammonia-lyase C-terminus MR_MLE PF01188.16 KKK21958.1 - 0.029 14.8 0.0 0.066 13.7 0.0 1.6 1 0 0 1 1 1 0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain 3H PF02829.9 KKK21958.1 - 0.11 12.4 0.1 0.63 10.1 0.0 2.2 2 0 0 2 2 2 0 3H domain AAA PF00004.24 KKK21959.1 - 4.7e-43 146.5 0.0 7.8e-43 145.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KKK21959.1 - 2.2e-07 31.0 0.0 1.1e-05 25.4 0.0 2.8 2 1 1 3 3 3 1 AAA ATPase domain AAA_2 PF07724.9 KKK21959.1 - 1.9e-06 27.9 0.0 6.5e-06 26.1 0.0 1.9 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 KKK21959.1 - 2.6e-06 27.2 0.1 5.5e-05 22.9 0.0 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 KKK21959.1 - 3.1e-06 26.3 0.0 5.7e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 KKK21959.1 - 6.9e-06 26.2 0.0 0.0013 18.8 0.0 2.5 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.8 KKK21959.1 - 0.00033 19.6 0.0 0.00073 18.5 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_19 PF13245.1 KKK21959.1 - 0.00069 19.3 0.0 0.0016 18.1 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain Zeta_toxin PF06414.7 KKK21959.1 - 0.0016 17.5 0.0 0.0032 16.5 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_17 PF13207.1 KKK21959.1 - 0.002 18.9 0.4 0.0064 17.2 0.1 2.2 2 1 0 2 2 1 1 AAA domain IstB_IS21 PF01695.12 KKK21959.1 - 0.0024 17.3 0.0 0.0046 16.3 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.8 KKK21959.1 - 0.0024 16.6 0.0 0.0052 15.5 0.0 1.5 1 0 0 1 1 1 1 TIP49 C-terminus AAA_14 PF13173.1 KKK21959.1 - 0.0029 17.5 0.0 0.0059 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.21 KKK21959.1 - 0.0044 16.5 0.0 0.015 14.8 0.0 1.9 1 1 0 1 1 1 1 Sigma-54 interaction domain Mg_chelatase PF01078.16 KKK21959.1 - 0.0056 15.8 0.0 0.011 14.9 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 KKK21959.1 - 0.006 16.7 0.0 0.011 15.8 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_18 PF13238.1 KKK21959.1 - 0.0062 16.8 0.1 0.02 15.2 0.0 2.0 2 1 0 2 2 1 1 AAA domain AAA_3 PF07726.6 KKK21959.1 - 0.0075 15.8 0.1 0.023 14.2 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 KKK21959.1 - 0.0084 15.9 0.0 0.022 14.6 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_25 PF13481.1 KKK21959.1 - 0.01 15.2 0.1 0.07 12.5 0.1 2.1 1 1 1 2 2 2 0 AAA domain Sigma54_activ_2 PF14532.1 KKK21959.1 - 0.012 15.6 0.0 0.035 14.1 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_28 PF13521.1 KKK21959.1 - 0.023 14.6 0.0 0.047 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 KKK21959.1 - 0.023 13.9 0.0 0.042 13.0 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_24 PF13479.1 KKK21959.1 - 0.024 14.2 0.1 0.048 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 KKK21959.1 - 0.028 13.5 0.0 0.11 11.5 0.0 2.0 1 1 1 2 2 2 0 KaiC AAA_11 PF13086.1 KKK21959.1 - 0.038 13.5 0.1 0.2 11.2 0.0 2.1 2 1 0 2 2 2 0 AAA domain UPF0079 PF02367.12 KKK21959.1 - 0.041 13.5 0.0 0.085 12.4 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Arch_ATPase PF01637.13 KKK21959.1 - 0.044 13.4 0.0 0.21 11.2 0.0 2.1 1 1 0 1 1 1 0 Archaeal ATPase Parvo_NS1 PF01057.12 KKK21959.1 - 0.066 12.0 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NACHT PF05729.7 KKK21959.1 - 0.073 12.7 0.0 0.22 11.1 0.0 1.8 2 0 0 2 2 2 0 NACHT domain AAA_30 PF13604.1 KKK21959.1 - 0.074 12.6 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain ResIII PF04851.10 KKK21959.1 - 0.082 12.7 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Thymidylate_kin PF02223.12 KKK21959.1 - 0.094 12.0 0.0 2.9 7.2 0.0 2.5 3 0 0 3 3 3 0 Thymidylate kinase Glyco_hydro_47 PF01532.15 KKK21960.1 - 6.4e-163 542.5 0.0 7.3e-163 542.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Bud13 PF09736.4 KKK21976.1 - 1.4e-47 161.6 4.2 1.4e-47 161.6 2.9 1.5 2 0 0 2 2 2 1 Pre-mRNA-splicing factor of RES complex DUF2335 PF10097.4 KKK21976.1 - 0.0028 17.2 2.7 0.0028 17.2 1.9 2.3 3 0 0 3 3 3 1 Predicted membrane protein (DUF2335) CAF-1_p150 PF11600.3 KKK21976.1 - 0.51 9.6 13.1 0.14 11.5 6.8 1.7 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF4407 PF14362.1 KKK21976.1 - 7.1 5.4 13.1 10 5.0 9.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Adap_comp_sub PF00928.16 KKK21977.1 - 1.7e-85 286.3 0.0 2.3e-85 285.8 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 KKK21977.1 - 0.0002 21.0 0.1 0.00036 20.2 0.1 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.4 KKK21977.1 - 0.03 13.5 0.1 0.047 12.8 0.1 1.3 1 0 0 1 1 1 0 Muniscin C-terminal mu homology domain Myb_DNA-bind_6 PF13921.1 KKK21978.1 - 0.00015 21.7 0.1 0.00026 21.0 0.1 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 KKK21978.1 - 0.0025 17.8 0.2 0.006 16.6 0.1 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain PRCC PF10253.4 KKK21978.1 - 0.31 11.7 3.3 1 10.0 0.0 2.1 2 0 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting SSB PF00436.20 KKK21979.1 - 8.2e-19 67.4 0.0 1e-18 67.1 0.0 1.1 1 0 0 1 1 1 1 Single-strand binding protein family Slp PF03843.8 KKK21979.1 - 0.12 11.3 0.1 6.1 5.8 0.0 2.0 2 0 0 2 2 2 0 Outer membrane lipoprotein Slp family DUF4203 PF13886.1 KKK21980.1 - 2.3e-34 118.7 20.8 3.2e-22 79.0 0.8 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF4203) Erf4 PF10256.4 KKK21980.1 - 3.4e-32 110.7 0.0 6.5e-32 109.8 0.0 1.5 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family 23S_rRNA_IVP PF05635.6 KKK21980.1 - 0.071 13.0 1.6 0.2 11.6 1.1 1.7 1 0 0 1 1 1 0 23S rRNA-intervening sequence protein Ldh_1_N PF00056.18 KKK21980.1 - 0.12 12.2 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain PgaD PF13994.1 KKK21980.1 - 0.13 11.7 0.1 0.4 10.1 0.1 1.8 1 0 0 1 1 1 0 PgaD-like protein STE3 PF02076.10 KKK21981.1 - 1.9e-103 345.4 9.0 2.3e-103 345.1 6.2 1.1 1 0 0 1 1 1 1 Pheromone A receptor Fungal_trans_2 PF11951.3 KKK21982.1 - 2.1e-09 36.5 1.2 1.4e-08 33.7 0.5 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK21982.1 - 2.3e-08 33.7 8.8 4e-08 33.0 6.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3433 PF11915.3 KKK21983.1 - 1e-34 118.5 18.3 2.1e-26 91.8 2.0 3.1 3 0 0 3 3 3 2 Protein of unknown function (DUF3433) RHINO PF15319.1 KKK21983.1 - 0.65 9.7 5.1 1.1 9.0 3.5 1.2 1 0 0 1 1 1 0 RAD9, RAD1, HUS1-interacting nuclear orphan protein Peptidase_C14 PF00656.17 KKK21985.1 - 7.2e-25 88.1 0.0 1.1e-24 87.4 0.0 1.2 1 0 0 1 1 1 1 Caspase domain ADH_N PF08240.7 KKK21986.1 - 1.7e-30 105.0 2.7 3.7e-30 103.8 1.9 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KKK21986.1 - 3.7e-27 94.4 0.1 1.9e-26 92.1 0.0 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KKK21986.1 - 3.3e-07 31.2 0.0 7.6e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Pyr_redox_3 PF13738.1 KKK21986.1 - 0.021 14.8 0.1 0.035 14.1 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KKK21986.1 - 0.1 12.4 0.4 0.19 11.5 0.2 1.4 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KKK21987.1 - 1.3e-19 71.0 0.0 4.5e-19 69.3 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KKK21987.1 - 2.8e-14 52.2 0.2 2.6e-12 45.7 0.0 2.4 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 KKK21987.1 - 1.7e-09 37.0 0.0 3.2e-07 29.6 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 KKK21987.1 - 1.9e-09 37.6 0.0 3.5e-08 33.5 0.0 2.5 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KKK21987.1 - 3.2e-07 30.2 0.1 1.2e-05 25.1 0.0 3.3 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 KKK21987.1 - 1.2e-05 24.5 0.1 3.5e-05 23.0 0.1 1.8 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 KKK21987.1 - 6.2e-05 23.3 0.6 0.31 11.4 0.0 3.3 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KKK21987.1 - 0.0033 16.3 1.2 0.0054 15.6 0.8 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 KKK21987.1 - 0.0053 15.2 0.3 0.013 14.0 0.1 1.7 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.19 KKK21987.1 - 0.0053 15.7 0.1 0.13 11.1 0.0 2.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.14 KKK21987.1 - 0.012 14.7 0.1 0.096 11.8 0.0 2.1 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 KKK21987.1 - 0.017 15.2 0.2 4.5 7.3 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase GIDA PF01134.17 KKK21987.1 - 0.022 13.6 0.8 0.23 10.2 0.3 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A Thi4 PF01946.12 KKK21987.1 - 0.045 12.8 0.0 0.53 9.3 0.0 2.3 2 0 0 2 2 2 0 Thi4 family NTF2 PF02136.15 KKK21987.1 - 0.11 12.8 0.0 0.21 11.9 0.0 1.4 1 0 0 1 1 1 0 Nuclear transport factor 2 (NTF2) domain Grp1_Fun34_YaaH PF01184.14 KKK21988.1 - 2.7e-22 79.1 13.5 3.7e-22 78.6 9.4 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF3784 PF12650.2 KKK21988.1 - 0.3 11.0 6.6 0.79 9.6 0.9 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3784) FxsA PF04186.8 KKK21988.1 - 2.3 7.8 8.0 4.6 6.8 0.1 2.4 2 1 0 2 2 2 0 FxsA cytoplasmic membrane protein Zn_clus PF00172.13 KKK21989.1 - 3.7e-08 33.1 11.3 8.5e-08 31.9 7.8 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain G-patch PF01585.18 KKK21990.1 - 1.4e-11 43.9 0.7 2.8e-11 43.0 0.5 1.5 1 0 0 1 1 1 1 G-patch domain RRM_1 PF00076.17 KKK21990.1 - 1.8e-08 33.8 4.1 0.00024 20.6 0.0 3.1 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KKK21990.1 - 7.3e-06 25.8 0.0 0.0097 15.8 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) G-patch_2 PF12656.2 KKK21990.1 - 8.4e-05 22.3 1.2 0.00027 20.7 0.8 1.9 1 0 0 1 1 1 1 DExH-box splicing factor binding site RRM_5 PF13893.1 KKK21990.1 - 0.011 15.6 0.3 0.035 13.9 0.0 1.9 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PRCC PF10253.4 KKK21991.1 - 0.015 16.0 1.1 0.027 15.1 0.8 1.4 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting ELM2 PF01448.19 KKK21991.1 - 0.44 11.2 2.4 4.5 7.9 0.0 2.7 2 2 0 2 2 2 0 ELM2 domain Pup PF05639.6 KKK21991.1 - 8.3 6.9 8.0 21 5.6 0.1 2.9 2 1 1 3 3 3 0 Pup-like protein Pectate_lyase_3 PF12708.2 KKK21992.1 - 2.5e-55 188.0 16.3 1.8e-43 149.2 1.6 2.9 3 0 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 KKK21992.1 - 0.032 13.6 0.3 0.15 11.5 0.0 2.2 2 0 0 2 2 2 0 N terminal extension of bacteriophage endosialidase GARS_A PF01071.14 KKK22009.1 - 8.6e-84 279.9 0.0 1.5e-83 279.1 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.10 KKK22009.1 - 2.3e-36 124.2 0.1 1.1e-35 122.1 0.0 2.3 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, N domain AIRS_C PF02769.17 KKK22009.1 - 2.1e-32 112.2 0.0 4.6e-32 111.1 0.0 1.6 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain GARS_C PF02843.11 KKK22009.1 - 1e-26 92.8 0.1 2.4e-26 91.7 0.1 1.7 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain ATP-grasp_4 PF13535.1 KKK22009.1 - 2.3e-11 43.7 0.0 7.4e-11 42.1 0.0 1.9 1 1 0 1 1 1 1 ATP-grasp domain AIRS PF00586.19 KKK22009.1 - 9.9e-09 35.3 0.5 5.5e-08 32.9 0.4 2.2 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain ATPgrasp_Ter PF15632.1 KKK22009.1 - 1.1e-08 34.2 0.0 2.1e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 KKK22009.1 - 7.9e-06 25.3 0.0 1.4e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.12 KKK22009.1 - 1.2e-05 24.6 0.0 2.3e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_3 PF02655.9 KKK22009.1 - 2.1e-05 24.4 0.0 8.4e-05 22.4 0.0 2.0 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp_2 PF08442.5 KKK22009.1 - 0.0014 18.0 0.0 0.0027 17.1 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 KKK22009.1 - 0.0015 18.0 0.0 0.0035 16.8 0.0 1.6 1 0 0 1 1 1 1 RimK-like ATP-grasp domain Dala_Dala_lig_C PF07478.8 KKK22009.1 - 0.035 13.5 0.0 0.061 12.6 0.0 1.4 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus tRNA_synt_1c_R1 PF04558.10 KKK22009.1 - 0.059 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Actin PF00022.14 KKK22010.1 - 6.8e-152 505.4 0.0 7.6e-152 505.2 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 KKK22010.1 - 0.034 14.5 0.0 0.11 12.9 0.0 1.8 1 1 1 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) LRR_6 PF13516.1 KKK22011.1 - 7.3 7.0 12.6 2e+02 2.5 0.0 7.6 9 0 0 9 9 9 0 Leucine Rich repeat Pet127 PF08634.5 KKK22012.1 - 3.7e-101 337.8 5.8 1.5e-51 175.1 0.4 2.1 1 1 1 2 2 2 2 Mitochondrial protein Pet127 Vps55 PF04133.9 KKK22014.1 - 1.2e-43 147.6 5.7 1.3e-43 147.5 3.9 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 TrbC PF04956.8 KKK22014.1 - 4.2 7.4 9.6 0.69 9.9 0.7 2.2 2 0 0 2 2 2 0 TrbC/VIRB2 family DUF1049 PF06305.6 KKK22014.1 - 5.1 6.6 12.3 3.9 7.0 2.8 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1049) IGPD PF00475.13 KKK22015.1 - 1.3e-56 190.5 0.3 1.6e-56 190.1 0.2 1.1 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase Arena_RNA_pol PF06317.6 KKK22015.1 - 0.16 8.5 0.0 0.2 8.1 0.0 1.0 1 0 0 1 1 1 0 Arenavirus RNA polymerase Fes1 PF08609.5 KKK22017.1 - 1.3e-35 121.7 6.7 2.7e-34 117.5 3.5 2.3 2 0 0 2 2 2 1 Nucleotide exchange factor Fes1 HEAT_2 PF13646.1 KKK22017.1 - 1.2e-12 47.9 0.8 3.5e-06 27.2 0.0 2.6 1 1 1 2 2 2 2 HEAT repeats HEAT PF02985.17 KKK22017.1 - 3.9e-07 29.5 0.1 0.035 14.1 0.0 2.7 2 0 0 2 2 2 2 HEAT repeat Arm PF00514.18 KKK22017.1 - 2e-06 27.4 0.0 0.0017 18.1 0.0 2.5 2 0 0 2 2 2 2 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.1 KKK22017.1 - 2e-06 28.1 0.1 3e-05 24.3 0.0 2.6 2 2 1 3 3 3 2 HEAT-like repeat AAA_22 PF13401.1 KKK22017.1 - 0.023 14.8 0.0 0.04 14.0 0.0 1.4 1 1 0 1 1 1 0 AAA domain Adaptin_N PF01602.15 KKK22017.1 - 0.041 12.1 0.1 0.1 10.9 0.0 1.5 1 1 0 1 1 1 0 Adaptin N terminal region V-ATPase_H_N PF03224.9 KKK22017.1 - 0.078 12.0 0.1 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 V-ATPase subunit H PSD2 PF07624.6 KKK22017.1 - 0.1 12.2 0.0 0.31 10.7 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1585) 2-Hacid_dh_C PF02826.14 KKK22018.1 - 1e-50 171.3 0.0 2e-50 170.3 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KKK22018.1 - 1.3e-14 53.8 0.0 1.7e-14 53.4 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 KKK22018.1 - 3.9e-05 23.5 0.0 8.3e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase GFO_IDH_MocA PF01408.17 KKK22018.1 - 0.045 14.2 0.0 0.15 12.5 0.0 1.9 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold Drf_GBD PF06371.8 KKK22019.1 - 2.3e-72 242.3 0.5 5.5e-72 241.0 0.0 1.9 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.11 KKK22019.1 - 1.4e-54 184.5 3.6 9.4e-54 181.8 0.0 2.6 2 1 1 3 3 3 2 Diaphanous FH3 Domain UPF0220 PF05255.6 KKK22020.1 - 4.6e-70 234.1 1.7 5.2e-70 234.0 1.2 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) G3P_antiterm PF04309.7 KKK22020.1 - 0.13 11.3 0.0 0.23 10.5 0.0 1.4 1 0 0 1 1 1 0 Glycerol-3-phosphate responsive antiterminator MBOAT PF03062.14 KKK22021.1 - 1.7e-42 145.6 5.1 5.1e-42 144.1 3.6 1.8 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family DUF679 PF05078.7 KKK22021.1 - 0.069 12.8 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF679) Sec1 PF00995.18 KKK22022.1 - 1.2e-150 502.8 0.0 1.4e-150 502.6 0.0 1.0 1 0 0 1 1 1 1 Sec1 family B12-binding PF02310.14 KKK22022.1 - 0.017 15.0 0.5 0.055 13.3 0.0 2.0 2 0 0 2 2 2 0 B12 binding domain tRNA-synt_1 PF00133.17 KKK22023.1 - 3.2e-57 193.8 0.0 3.1e-37 127.8 0.0 5.8 2 1 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) Suc_Fer-like PF06999.7 KKK22023.1 - 1.3e-41 143.0 0.0 2.3e-41 142.3 0.0 1.4 1 0 0 1 1 1 1 Sucrase/ferredoxin-like tRNA-synt_1_2 PF13603.1 KKK22023.1 - 2e-40 138.0 0.0 3.2e-40 137.4 0.0 1.3 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.6 KKK22023.1 - 4.5e-29 101.2 0.0 1.4e-23 83.1 0.0 3.9 3 1 0 3 3 3 2 tRNA synthetases class I (M) Abi PF02517.11 KKK22023.1 - 3.4e-14 52.7 6.6 1.3e-13 50.9 4.6 2.0 1 0 0 1 1 1 1 CAAX protease self-immunity Anticodon_1 PF08264.8 KKK22023.1 - 1.2e-09 38.0 0.0 2.4e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1d PF00750.14 KKK22023.1 - 0.0032 16.3 0.0 0.0057 15.5 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (R) tRNA-synt_1e PF01406.14 KKK22023.1 - 0.21 10.6 0.0 11 5.0 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain adh_short PF00106.20 KKK22025.1 - 4e-18 65.8 0.0 5.5e-18 65.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KKK22025.1 - 1.1e-08 34.9 0.0 1.6e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 KR domain Lysine_decarbox PF03641.9 KKK22026.1 - 4.9e-26 91.1 0.0 1.3e-25 89.7 0.0 1.7 1 1 0 1 1 1 1 Possible lysine decarboxylase Proteasome PF00227.21 KKK22027.1 - 2.7e-49 167.0 0.1 3.4e-49 166.7 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 KKK22027.1 - 2.8e-12 45.7 0.3 4.4e-12 45.0 0.2 1.3 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature APH PF01636.18 KKK22028.1 - 2.3e-17 63.5 0.1 1.5e-06 28.1 0.0 4.0 4 0 0 4 4 4 3 Phosphotransferase enzyme family DUF3684 PF12449.3 KKK22029.1 - 0 1512.1 0.0 0 1511.3 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3684) Chorismate_bind PF00425.13 KKK22029.1 - 7.6e-63 212.2 0.0 8.7e-62 208.7 0.0 2.2 1 1 0 1 1 1 1 chorismate binding enzyme Med6 PF04934.9 KKK22029.1 - 6.1e-41 139.2 0.0 1.9e-40 137.6 0.0 1.9 2 0 0 2 2 2 1 MED6 mediator sub complex component GATase PF00117.23 KKK22029.1 - 4.6e-26 91.4 0.0 3.1e-25 88.7 0.0 2.1 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.8 KKK22029.1 - 6.9e-10 39.0 0.0 2.5e-09 37.2 0.0 2.0 1 0 0 1 1 1 1 Anthranilate synthase component I, N terminal region HATPase_c_3 PF13589.1 KKK22029.1 - 0.00028 20.5 0.0 0.00079 19.0 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Peptidase_C26 PF07722.8 KKK22029.1 - 0.00035 20.0 0.1 0.00092 18.7 0.0 1.7 1 0 0 1 1 1 1 Peptidase C26 WLM PF08325.5 KKK22029.1 - 8.8 6.1 7.6 0.47 10.3 0.0 2.6 3 0 0 3 3 3 0 WLM domain TRAPPC9-Trs120 PF08626.6 KKK22030.1 - 3.6e-150 501.5 0.0 5.9e-150 500.8 0.0 1.2 1 0 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit MFS_1 PF07690.11 KKK22035.1 - 8.1e-47 159.6 28.0 8.1e-47 159.6 19.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KKK22035.1 - 1.1e-10 40.7 13.5 1.1e-10 40.7 9.3 2.5 2 1 0 2 2 2 2 Sugar (and other) transporter OATP PF03137.15 KKK22035.1 - 0.0016 16.5 9.4 0.71 7.8 0.0 3.5 2 1 1 3 3 3 3 Organic Anion Transporter Polypeptide (OATP) family DUF2015 PF09435.5 KKK22037.1 - 1.8e-48 163.5 0.0 2e-48 163.3 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2015) DUF3829 PF12889.2 KKK22037.1 - 0.089 11.9 0.0 0.097 11.8 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3829) RRM_1 PF00076.17 KKK22038.1 - 3e-35 119.6 0.0 1.2e-16 60.1 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KKK22038.1 - 8.5e-20 70.5 0.0 7.4e-09 35.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KKK22038.1 - 3.6e-16 58.7 0.0 7.7e-07 28.8 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.6 KKK22038.1 - 0.0055 16.1 0.2 0.38 10.2 0.0 2.4 2 0 0 2 2 2 1 Ribonuclease B OB domain Limkain-b1 PF11608.3 KKK22038.1 - 0.026 14.2 0.2 0.54 10.0 0.0 2.1 2 0 0 2 2 2 0 Limkain b1 Cas_Cas2CT1978 PF09707.5 KKK22038.1 - 0.097 12.6 0.0 6.8 6.7 0.0 2.3 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Cas2CT1978) DUF605 PF04652.11 KKK22038.1 - 0.77 9.0 14.4 1 8.6 10.0 1.1 1 0 0 1 1 1 0 Vta1 like Ribosomal_L28e PF01778.12 KKK22039.1 - 3.7e-45 153.0 0.4 5.1e-45 152.6 0.3 1.2 1 0 0 1 1 1 1 Ribosomal L28e protein family WD40 PF00400.27 KKK22040.1 - 2e-75 246.2 10.6 7.6e-13 47.7 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.5 KKK22040.1 - 4.1e-16 58.9 6.6 6.3e-16 58.3 4.6 1.3 1 0 0 1 1 1 1 Tup N-terminal Cytochrom_D1 PF02239.11 KKK22040.1 - 9.7e-06 24.1 1.3 0.00042 18.7 0.2 2.6 1 1 2 3 3 3 2 Cytochrome D1 heme domain Nup160 PF11715.3 KKK22040.1 - 9.2e-05 20.7 0.1 0.072 11.2 0.0 3.0 1 1 2 3 3 3 2 Nucleoporin Nup120/160 eIF2A PF08662.6 KKK22040.1 - 0.00022 21.0 0.0 0.031 13.9 0.0 2.9 1 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.1 KKK22040.1 - 0.01 14.9 0.0 4.4 6.3 0.0 2.9 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal PQQ_2 PF13360.1 KKK22040.1 - 0.028 13.8 0.9 3.7 6.9 0.1 2.9 2 1 1 3 3 3 0 PQQ-like domain zf-C2H2_4 PF13894.1 KKK22041.1 - 6.4e-15 54.3 19.2 0.0013 18.9 0.3 4.8 4 0 0 4 4 4 4 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KKK22041.1 - 9.5e-15 54.0 23.3 7.1e-08 32.3 0.5 4.8 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2 PF00096.21 KKK22041.1 - 7.5e-13 47.9 43.1 0.00012 22.1 0.4 4.8 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-met PF12874.2 KKK22041.1 - 0.0064 16.6 12.0 0.059 13.5 0.7 3.8 4 0 0 4 4 4 2 Zinc-finger of C2H2 type Ogr_Delta PF04606.7 KKK22041.1 - 0.019 14.5 3.6 1.5 8.5 0.0 3.7 4 0 0 4 4 4 0 Ogr/Delta-like zinc finger zf-C2H2_6 PF13912.1 KKK22041.1 - 2.5 8.1 16.4 1.5 8.7 0.8 4.5 4 0 0 4 4 4 0 C2H2-type zinc finger Mito_carr PF00153.22 KKK22042.1 - 1.2e-48 162.7 0.1 2e-23 81.8 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein MFS_1 PF07690.11 KKK22058.1 - 1.6e-42 145.4 45.6 1.6e-42 145.4 31.6 2.1 2 0 0 2 2 2 1 Major Facilitator Superfamily Aldolase_II PF00596.16 KKK22059.1 - 2.1e-34 118.7 0.0 2.6e-34 118.4 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain DUF3148 PF11347.3 KKK22059.1 - 0.13 11.8 0.0 0.28 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3148) Aa_trans PF01490.13 KKK22060.1 - 1.6e-27 96.0 44.4 3.5e-14 52.1 9.1 2.0 1 1 1 2 2 2 2 Transmembrane amino acid transporter protein K1 PF02960.9 KKK22060.1 - 0.54 10.3 0.0 0.54 10.3 0.0 2.9 2 1 0 2 2 2 0 K1 glycoprotein DAO PF01266.19 KKK22061.1 - 1.2e-28 100.0 0.0 1.4e-28 99.8 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KKK22061.1 - 0.0006 18.7 0.0 0.00087 18.2 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 KKK22061.1 - 0.00088 19.2 0.2 0.0026 17.7 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 KKK22061.1 - 0.025 13.6 0.3 0.038 13.0 0.2 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.22 KKK22061.1 - 0.045 14.1 0.1 0.14 12.5 0.1 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Sulfotransfer_3 PF13469.1 KKK22061.1 - 0.052 14.4 0.2 0.096 13.6 0.0 1.5 2 0 0 2 2 2 0 Sulfotransferase family Pyr_redox_2 PF07992.9 KKK22061.1 - 0.097 12.5 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KKK22061.1 - 0.11 11.5 0.1 0.11 11.5 0.1 1.7 2 0 0 2 2 2 0 Thi4 family DLH PF01738.13 KKK22062.1 - 1.4e-23 83.3 0.0 1.7e-23 83.0 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 KKK22062.1 - 2.2e-06 27.4 0.0 3e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF915 PF06028.6 KKK22062.1 - 0.02 13.9 0.0 0.027 13.5 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_6 PF12697.2 KKK22062.1 - 0.022 14.6 0.0 0.14 12.0 0.0 1.9 1 1 1 2 2 2 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KKK22062.1 - 0.069 12.6 0.0 0.26 10.8 0.0 1.7 2 0 0 2 2 2 0 alpha/beta hydrolase fold Aldedh PF00171.17 KKK22063.1 - 1.5e-161 537.8 0.2 1.6e-161 537.7 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 KKK22063.1 - 0.028 13.6 0.1 0.33 10.1 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1487) DUF126 PF01989.11 KKK22063.1 - 1.6 8.4 4.3 10 5.8 0.2 3.3 3 1 1 4 4 4 0 Protein of unknown function DUF126 p450 PF00067.17 KKK22064.1 - 2.1e-40 138.6 0.0 2.5e-40 138.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Pyr_redox_3 PF13738.1 KKK22065.1 - 3.2e-18 66.5 0.0 4.9e-18 65.9 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KKK22065.1 - 5.7e-16 57.8 0.0 1.6e-15 56.3 0.0 1.7 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 KKK22065.1 - 1.1e-07 31.7 0.0 3e-07 30.3 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 KKK22065.1 - 0.0001 22.0 0.1 0.0003 20.5 0.0 1.9 2 0 0 2 2 2 1 FAD-NAD(P)-binding 2-Hacid_dh_C PF02826.14 KKK22065.1 - 0.0022 17.1 0.0 0.0043 16.2 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain K_oxygenase PF13434.1 KKK22065.1 - 0.022 13.6 0.1 0.19 10.6 0.0 2.3 3 0 0 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.22 KKK22065.1 - 0.085 13.2 0.0 1.6 9.1 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ADH_zinc_N PF00107.21 KKK22066.1 - 2.4e-16 59.4 0.0 3.5e-16 58.9 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KKK22066.1 - 3.2e-07 31.2 0.0 5.3e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_10 PF13460.1 KKK22066.1 - 0.023 14.7 0.0 0.039 13.9 0.0 1.4 1 0 0 1 1 1 0 NADH(P)-binding Zn_clus PF00172.13 KKK22067.1 - 1.7e-05 24.5 12.3 1.7e-05 24.5 8.5 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.17 KKK22068.1 - 1e-34 119.9 0.0 1.4e-34 119.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 AA_permease_2 PF13520.1 KKK22069.1 - 1.4e-27 96.3 16.5 1.6e-27 96.1 11.4 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KKK22069.1 - 1.6e-21 76.2 16.0 2.1e-21 75.8 11.1 1.0 1 0 0 1 1 1 1 Amino acid permease adh_short PF00106.20 KKK22070.1 - 3.9e-25 88.7 0.0 5e-25 88.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KKK22070.1 - 5.4e-24 85.2 0.0 7e-24 84.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KKK22070.1 - 2.5e-07 30.5 0.0 5.8e-07 29.3 0.0 1.5 1 1 0 1 1 1 1 KR domain Kp4 PF09044.5 KKK22070.1 - 0.12 12.1 0.0 0.27 11.0 0.0 1.6 1 0 0 1 1 1 0 Kp4 Eno-Rase_NADH_b PF12242.3 KKK22070.1 - 0.15 11.9 1.5 0.33 10.7 0.7 1.7 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Transaldolase PF00923.14 KKK22071.1 - 3.2e-76 256.2 0.0 3.6e-76 256.0 0.0 1.0 1 0 0 1 1 1 1 Transaldolase Chorismate_synt PF01264.16 KKK22071.1 - 0.046 12.2 0.0 0.065 11.7 0.0 1.1 1 0 0 1 1 1 0 Chorismate synthase Abhydrolase_3 PF07859.8 KKK22072.1 - 2e-43 148.4 0.0 2.7e-43 148.0 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 KKK22072.1 - 7.8e-09 34.7 0.3 5.6e-08 31.9 0.2 2.0 1 1 0 1 1 1 1 Carboxylesterase family Patatin PF01734.17 KKK22072.1 - 0.065 13.1 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Patatin-like phospholipase ADH_N PF08240.7 KKK22073.1 - 5.5e-30 103.3 1.3 1.8e-29 101.7 0.0 2.3 3 1 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KKK22073.1 - 1.8e-19 69.5 0.1 3.2e-19 68.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KKK22073.1 - 0.001 19.9 0.0 0.0032 18.3 0.0 1.9 1 1 0 1 1 1 1 Zinc-binding dehydrogenase HI0933_like PF03486.9 KKK22073.1 - 0.0027 16.2 0.2 0.0038 15.7 0.2 1.2 1 0 0 1 1 1 1 HI0933-like protein AdoHcyase_NAD PF00670.16 KKK22073.1 - 0.0041 16.9 0.4 0.11 12.2 0.3 2.2 2 0 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Pyr_redox PF00070.22 KKK22073.1 - 0.0063 16.8 0.0 0.039 14.3 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_18 PF12847.2 KKK22073.1 - 0.11 13.0 0.0 0.21 12.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain 2-Hacid_dh_C PF02826.14 KKK22073.1 - 0.16 11.0 0.0 0.27 10.3 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Aldo_ket_red PF00248.16 KKK22074.1 - 5e-50 169.9 0.0 6e-50 169.6 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Cupin_6 PF12852.2 KKK22075.1 - 0.00059 19.5 0.0 0.00075 19.1 0.0 1.2 1 0 0 1 1 1 1 Cupin Cupin_3 PF05899.7 KKK22075.1 - 0.00069 18.9 0.0 0.0012 18.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_2 PF07883.6 KKK22075.1 - 0.011 15.2 0.0 0.018 14.5 0.0 1.3 1 0 0 1 1 1 0 Cupin domain SprB PF13573.1 KKK22075.1 - 0.036 13.6 0.2 0.084 12.4 0.1 1.5 1 0 0 1 1 1 0 SprB repeat AraC_binding_2 PF14525.1 KKK22075.1 - 0.1 12.1 0.0 0.14 11.6 0.0 1.1 1 0 0 1 1 1 0 AraC-binding-like domain AA_permease_2 PF13520.1 KKK22076.1 - 6.1e-34 117.2 32.7 1.9e-32 112.3 22.7 2.0 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KKK22076.1 - 2e-14 52.7 24.6 2e-14 52.7 17.0 2.0 1 1 1 2 2 2 1 Amino acid permease Gram_pos_anchor PF00746.16 KKK22076.1 - 0.053 13.3 0.2 0.053 13.3 0.1 2.6 3 0 0 3 3 3 0 Gram positive anchor 4HBT_3 PF13622.1 KKK22077.1 - 1.2e-50 172.6 0.0 1.5e-50 172.3 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.10 KKK22077.1 - 0.0001 21.9 0.2 0.56 9.8 0.0 3.8 2 2 1 3 3 3 2 Acyl-CoA thioesterase WD40 PF00400.27 KKK22077.1 - 0.076 12.9 0.0 0.28 11.1 0.0 1.9 1 0 0 1 1 1 0 WD domain, G-beta repeat Ribosomal_S6 PF01250.12 KKK22078.1 - 1e-07 31.7 0.0 1.2e-07 31.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S6 MerR_1 PF13411.1 KKK22078.1 - 0.021 14.5 0.1 0.077 12.7 0.0 1.8 2 0 0 2 2 2 0 MerR HTH family regulatory protein NmrA PF05368.8 KKK22079.1 - 5.4e-31 107.6 0.0 7.1e-31 107.2 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KKK22079.1 - 2.8e-10 40.5 0.0 4.1e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KKK22079.1 - 0.00028 20.4 0.0 0.022 14.2 0.0 2.3 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 KKK22079.1 - 0.0043 15.9 0.0 0.026 13.4 0.0 1.9 2 0 0 2 2 2 1 Male sterility protein KR PF08659.5 KKK22079.1 - 0.0079 15.8 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 KKK22079.1 - 0.0089 15.9 0.0 0.015 15.1 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 KKK22079.1 - 0.11 11.3 0.0 13 4.5 0.0 2.5 3 0 0 3 3 3 0 Polysaccharide biosynthesis protein Chs3p PF12271.3 KKK22081.1 - 1.7e-138 460.5 14.6 1.9e-138 460.3 10.1 1.0 1 0 0 1 1 1 1 Chitin synthase III catalytic subunit Abhydrolase_5 PF12695.2 KKK22082.1 - 2.9e-06 27.0 0.0 5.5e-06 26.1 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 KKK22082.1 - 0.00019 21.1 0.0 0.00039 20.0 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.2 KKK22082.1 - 0.0012 18.8 3.7 0.0027 17.6 2.6 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 KKK22082.1 - 0.0018 17.9 0.0 0.003 17.1 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF676 PF05057.9 KKK22082.1 - 0.018 14.3 0.0 0.048 12.9 0.0 1.7 1 1 0 1 1 1 0 Putative serine esterase (DUF676) LCAT PF02450.10 KKK22082.1 - 0.033 13.1 0.1 0.066 12.1 0.0 1.5 2 0 0 2 2 2 0 Lecithin:cholesterol acyltransferase Abhydrolase_2 PF02230.11 KKK22082.1 - 0.054 12.9 0.0 0.13 11.6 0.0 1.6 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Tom5 PF10642.4 KKK22083.1 - 6.4e-22 76.9 0.2 6.8e-22 76.8 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit or translocase Med26 PF08711.6 KKK22084.1 - 1.6e-13 49.9 0.0 2.9e-13 49.0 0.0 1.4 1 0 0 1 1 1 1 TFIIS helical bundle-like domain HIG_1_N PF04588.8 KKK22085.1 - 5.8e-06 25.9 4.2 1.2e-05 24.9 2.9 1.6 1 1 0 1 1 1 1 Hypoxia induced protein conserved region CcmD PF04995.9 KKK22085.1 - 0.053 13.2 1.2 0.19 11.4 0.8 1.9 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) PTR2 PF00854.16 KKK22086.1 - 9.9e-43 146.3 15.8 9.8e-23 80.5 4.7 2.2 2 0 0 2 2 2 2 POT family MFS_1 PF07690.11 KKK22086.1 - 0.00011 21.0 24.3 0.00011 21.0 16.9 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF21 PF01595.15 KKK22086.1 - 2.3 7.4 6.0 2.7 7.2 0.2 3.1 2 1 1 3 3 3 0 Domain of unknown function DUF21 Cyclase PF04199.8 KKK22087.1 - 1.5e-05 24.7 0.0 2.7e-05 23.9 0.0 1.5 1 1 0 1 1 1 1 Putative cyclase Cupin_3 PF05899.7 KKK22087.1 - 0.0045 16.3 0.0 0.0082 15.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF861) HMG_box_2 PF09011.5 KKK22087.1 - 0.14 12.5 0.2 0.31 11.4 0.1 1.6 2 0 0 2 2 2 0 HMG-box domain RHD3 PF05879.7 KKK22088.1 - 0 1082.3 0.0 0 1082.0 0.0 1.0 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.14 KKK22088.1 - 2.6e-08 33.2 0.3 4.4e-08 32.5 0.2 1.2 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain Dynamin_N PF00350.18 KKK22088.1 - 2.4e-06 27.4 0.0 4.8e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 KKK22088.1 - 0.00013 21.9 0.0 0.00029 20.7 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_28 PF13521.1 KKK22088.1 - 0.0012 18.8 0.0 0.0035 17.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain Miro PF08477.8 KKK22088.1 - 0.0025 18.2 0.0 0.0053 17.2 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein 4HBT_2 PF13279.1 KKK22089.1 - 1.7e-09 38.1 0.0 2.8e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily Nup54 PF13874.1 KKK22090.1 - 5.2e-45 152.5 0.6 1.5e-44 151.0 0.0 1.9 1 1 0 1 1 1 1 Nucleoporin complex subunit 54 Nucleoporin_FG PF13634.1 KKK22090.1 - 1.4e-08 34.9 96.5 1.4e-07 31.6 40.1 2.9 1 1 1 2 2 2 2 Nucleoporin FG repeat region NBP1 PF08537.5 KKK22090.1 - 1.6 7.8 6.6 2.9 7.0 4.6 1.4 1 1 0 1 1 1 0 Fungal Nap binding protein NBP1 IF3_C PF00707.17 KKK22091.1 - 7.2e-18 64.1 2.2 1.1e-17 63.5 1.5 1.3 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain mIF3 PF14877.1 KKK22091.1 - 1.8e-06 27.4 2.5 8.8e-06 25.2 0.5 2.4 1 1 2 3 3 3 1 Mitochondrial translation initiation factor IF3_N PF05198.11 KKK22091.1 - 0.00022 21.0 0.0 0.00058 19.7 0.0 1.7 2 0 0 2 2 2 1 Translation initiation factor IF-3, N-terminal domain ALO PF04030.9 KKK22091.1 - 0.098 12.2 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 D-arabinono-1,4-lactone oxidase GTP_EFTU PF00009.22 KKK22092.1 - 6.4e-60 201.8 0.1 9e-60 201.3 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 KKK22092.1 - 3e-20 72.2 0.0 1.9e-19 69.6 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 KKK22092.1 - 9.9e-18 64.0 2.2 2.5e-17 62.7 1.6 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KKK22092.1 - 1.3e-05 25.0 0.0 2.4e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.1 KKK22092.1 - 0.0025 17.3 0.2 0.0062 16.1 0.2 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 4 Miro PF08477.8 KKK22092.1 - 0.0045 17.4 0.0 0.0076 16.7 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein PduV-EutP PF10662.4 KKK22092.1 - 0.09 12.2 0.3 4.9 6.6 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation cobW PF02492.14 KKK22092.1 - 0.099 12.0 0.6 0.78 9.1 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF4598 PF15370.1 KKK22093.1 - 7.6e-35 119.5 6.3 7.6e-35 119.5 4.4 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4598) IclR PF01614.13 KKK22093.1 - 0.15 11.7 0.1 0.32 10.6 0.0 1.5 2 0 0 2 2 2 0 Bacterial transcriptional regulator DUF2201_N PF13203.1 KKK22093.1 - 3.8 6.5 8.2 0.51 9.4 2.6 1.6 1 1 1 2 2 2 0 Putative metallopeptidase domain GDA1_CD39 PF01150.12 KKK22094.1 - 1.5e-91 307.1 0.0 1.9e-91 306.7 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family COMPASS-Shg1 PF05205.7 KKK22095.1 - 3.2e-30 104.5 0.3 7e-30 103.4 0.2 1.6 1 0 0 1 1 1 1 COMPASS (Complex proteins associated with Set1p) component shg1 IF4E PF01652.13 KKK22096.1 - 5.7e-37 126.7 0.1 7.1e-37 126.4 0.1 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Cation_efflux PF01545.16 KKK22097.1 - 3.1e-33 115.0 8.0 4e-33 114.7 5.6 1.1 1 0 0 1 1 1 1 Cation efflux family GCV_H PF01597.14 KKK22099.1 - 3e-37 127.0 0.5 3.6e-37 126.7 0.3 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein Biotin_lipoyl PF00364.17 KKK22099.1 - 0.062 12.9 0.3 0.15 11.6 0.1 1.7 1 1 0 1 1 1 0 Biotin-requiring enzyme zf-rbx1 PF12678.2 KKK22100.1 - 3.5e-09 36.6 0.3 7.4e-09 35.5 0.2 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 KKK22100.1 - 7.2e-09 35.3 10.5 1.3e-07 31.2 7.3 2.3 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 KKK22100.1 - 5.2e-07 29.2 0.6 9.1e-07 28.4 0.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KKK22100.1 - 1e-06 28.3 3.1 3.1e-06 26.7 2.2 1.8 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KKK22100.1 - 2.4e-06 27.0 5.4 9.2e-06 25.2 3.7 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KKK22100.1 - 2.4e-05 24.2 2.9 2.4e-05 24.2 2.0 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KKK22100.1 - 0.0067 16.2 1.2 0.016 15.0 0.8 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 KKK22100.1 - 0.76 9.5 4.4 0.62 9.8 1.0 2.4 1 1 1 2 2 2 0 RING-type zinc-finger DUF3671 PF12420.3 KKK22100.1 - 1 9.3 2.5 18 5.3 1.7 2.4 2 0 0 2 2 2 0 Protein of unknown function FANCL_C PF11793.3 KKK22100.1 - 2.7 7.9 5.9 13 5.8 4.1 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain DUF3099 PF11298.3 KKK22100.1 - 4.1 7.2 5.9 3.2 7.5 0.9 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3099) DinB_2 PF12867.2 KKK22103.1 - 0.099 12.9 0.7 0.11 12.8 0.5 1.1 1 0 0 1 1 1 0 DinB superfamily PCI PF01399.22 KKK22104.1 - 3.3e-07 30.5 0.0 5.4e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 PCI domain RNase_P_Rpp14 PF01900.14 KKK22104.1 - 0.012 15.5 0.1 0.019 14.8 0.1 1.5 1 1 0 1 1 1 0 Rpp14/Pop5 family ADK PF00406.17 KKK22105.1 - 1.3e-40 138.7 0.0 1e-38 132.5 0.0 2.0 1 1 0 1 1 1 1 Adenylate kinase AAA_18 PF13238.1 KKK22105.1 - 6.7e-09 36.1 0.0 9.7e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KKK22105.1 - 6.6e-07 30.1 0.1 2e-06 28.5 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KKK22105.1 - 9.8e-07 28.7 0.1 2.3e-05 24.3 0.1 2.2 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 KKK22105.1 - 3.6e-06 26.4 0.1 1.5e-05 24.4 0.0 1.9 1 1 0 1 1 1 1 Thymidylate kinase AAA_19 PF13245.1 KKK22105.1 - 0.13 12.0 0.6 0.4 10.4 0.0 2.1 2 0 0 2 2 2 0 Part of AAA domain OmdA PF13376.1 KKK22110.1 - 6.8e-16 57.6 0.1 1.2e-15 56.8 0.1 1.5 1 0 0 1 1 1 1 Bacteriocin-protection, YdeI or OmpD-Associated Fungal_trans_2 PF11951.3 KKK22111.1 - 5.1e-05 22.0 0.1 0.0024 16.5 0.0 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain Isochorismatase PF00857.15 KKK22112.1 - 9.4e-21 74.5 0.0 1.7e-20 73.6 0.0 1.4 1 0 0 1 1 1 1 Isochorismatase family DUF2809 PF10990.3 KKK22112.1 - 0.1 13.0 0.0 0.25 11.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2809) AA_permease_2 PF13520.1 KKK22117.1 - 5e-65 219.7 47.3 6e-65 219.4 32.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KKK22117.1 - 1.9e-20 72.6 38.8 2.6e-20 72.2 26.9 1.2 1 0 0 1 1 1 1 Amino acid permease QCR10 PF09796.4 KKK22118.1 - 9.8e-30 102.0 0.4 1.3e-29 101.6 0.2 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) Coatomer_WDAD PF04053.9 KKK22119.1 - 1e-169 565.0 0.0 2.7e-169 563.6 0.0 1.7 2 0 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.27 KKK22119.1 - 9e-47 155.3 9.8 5.2e-10 38.8 0.1 7.9 8 0 0 8 8 8 6 WD domain, G-beta repeat Nup160 PF11715.3 KKK22119.1 - 0.00044 18.5 3.3 0.067 11.3 0.1 4.2 2 2 1 4 4 4 2 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 KKK22119.1 - 0.0029 17.3 0.0 2 8.2 0.0 3.3 2 0 0 2 2 2 2 Ciliary BBSome complex subunit 2, middle region Thioredoxin PF00085.15 KKK22120.1 - 5.1e-47 157.8 0.1 4e-25 87.5 0.0 4.4 3 1 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.1 KKK22120.1 - 1.5e-12 47.6 0.0 0.0018 18.1 0.0 5.1 3 1 2 5 5 5 3 Thioredoxin-like domain Thioredoxin_2 PF13098.1 KKK22120.1 - 3.4e-10 40.0 0.4 0.029 14.5 0.1 4.4 3 1 0 3 3 3 3 Thioredoxin-like domain Thioredoxin_8 PF13905.1 KKK22120.1 - 3.5e-07 30.2 0.1 0.003 17.6 0.0 4.1 3 1 0 3 3 3 2 Thioredoxin-like Thioredoxin_7 PF13899.1 KKK22120.1 - 0.00065 19.6 2.2 0.0052 16.7 0.2 2.9 3 0 0 3 3 3 1 Thioredoxin-like Thioredoxin_3 PF13192.1 KKK22120.1 - 0.0013 18.5 0.1 0.28 11.0 0.0 2.8 3 0 0 3 3 3 1 Thioredoxin domain HyaE PF07449.6 KKK22120.1 - 0.0013 18.6 0.0 1.1 9.2 0.0 3.2 4 0 0 4 4 4 1 Hydrogenase-1 expression protein HyaE AhpC-TSA PF00578.16 KKK22120.1 - 0.0073 15.9 0.7 0.18 11.4 0.1 3.2 4 0 0 4 4 4 1 AhpC/TSA family GDYXXLXY PF14345.1 KKK22120.1 - 0.036 13.9 0.0 0.21 11.4 0.0 2.0 2 0 0 2 2 2 0 GDYXXLXY protein Prophage_tail PF06605.6 KKK22120.1 - 0.11 11.4 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 Prophage endopeptidase tail ETC_C1_NDUFA5 PF04716.9 KKK22121.1 - 8.2e-23 79.6 0.1 8.2e-23 79.6 0.1 2.8 3 0 0 3 3 3 1 ETC complex I subunit conserved region Trypan_PARP PF05887.6 KKK22121.1 - 0.11 12.3 4.0 0.18 11.5 2.8 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Cullin PF00888.17 KKK22140.1 - 2.8e-125 419.1 12.0 3.7e-125 418.7 8.3 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 KKK22140.1 - 4.7e-27 93.5 0.3 2e-26 91.6 0.2 2.2 1 0 0 1 1 1 1 Cullin protein neddylation domain Corona_S2 PF01601.11 KKK22141.1 - 0.0088 14.1 7.1 0.012 13.7 4.9 1.0 1 0 0 1 1 1 1 Coronavirus S2 glycoprotein Prominin PF05478.6 KKK22141.1 - 2.6 5.4 13.4 3.3 5.1 9.3 1.0 1 0 0 1 1 1 0 Prominin CwfJ_C_1 PF04677.10 KKK22142.1 - 1.3e-24 86.2 0.0 2e-24 85.5 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 KKK22142.1 - 2.6e-22 79.1 0.0 4.9e-22 78.2 0.0 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 DRIM PF07539.7 KKK22143.1 - 6e-46 155.3 0.0 2.5e-45 153.3 0.0 2.2 1 0 0 1 1 1 1 Down-regulated in metastasis HEAT PF02985.17 KKK22143.1 - 0.0016 18.3 4.7 2.2 8.5 0.0 7.0 9 0 0 9 9 9 1 HEAT repeat RRM_1 PF00076.17 KKK22145.1 - 5e-26 90.1 0.3 3.3e-12 45.8 0.2 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KKK22145.1 - 6e-18 64.4 0.0 8e-10 38.4 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KKK22145.1 - 3.1e-17 62.3 0.0 1.9e-07 30.9 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) ATP-synt_D PF01813.12 KKK22146.1 - 2.5e-65 219.7 1.8 3.5e-65 219.2 1.3 1.2 1 0 0 1 1 1 1 ATP synthase subunit D Nup54 PF13874.1 KKK22146.1 - 0.96 9.1 5.9 1.3 8.6 0.2 2.4 2 1 0 2 2 2 0 Nucleoporin complex subunit 54 TPR_12 PF13424.1 KKK22147.1 - 3.5e-11 42.8 2.5 0.057 13.3 0.0 7.5 7 1 0 7 7 7 1 Tetratricopeptide repeat TPR_14 PF13428.1 KKK22147.1 - 4.7e-11 42.2 14.9 1.9 9.3 0.0 10.8 11 2 2 13 13 10 3 Tetratricopeptide repeat Suf PF05843.9 KKK22147.1 - 6.8e-11 42.4 11.9 0.029 14.1 0.0 6.2 3 2 3 6 6 6 5 Suppressor of forked protein (Suf) TPR_19 PF14559.1 KKK22147.1 - 5.8e-08 32.9 0.3 2.1 8.7 0.0 5.7 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.1 KKK22147.1 - 1.5e-07 30.9 5.0 0.42 10.2 0.0 6.7 8 1 0 8 8 8 2 TPR repeat TPR_2 PF07719.12 KKK22147.1 - 2.3e-06 27.0 11.6 0.96 9.5 0.0 7.3 8 0 0 8 8 7 2 Tetratricopeptide repeat Mad3_BUB1_I PF08311.7 KKK22147.1 - 8.9e-06 25.5 15.0 1.7 8.4 0.1 7.1 7 1 0 7 7 7 2 Mad3/BUB1 homology region 1 TPR_8 PF13181.1 KKK22147.1 - 2.4e-05 23.7 5.6 1.9 8.4 0.0 6.7 7 1 0 7 7 6 1 Tetratricopeptide repeat TPR_16 PF13432.1 KKK22147.1 - 3.7e-05 24.2 9.6 0.13 12.9 0.0 6.6 7 1 1 8 8 8 2 Tetratricopeptide repeat NRDE-2 PF08424.5 KKK22147.1 - 6.5e-05 21.9 12.6 0.021 13.7 0.1 5.4 3 2 3 6 6 6 3 NRDE-2, necessary for RNA interference TPR_7 PF13176.1 KKK22147.1 - 0.00015 21.2 3.1 11 6.1 0.0 7.2 6 1 1 7 7 7 0 Tetratricopeptide repeat HAT PF02184.11 KKK22147.1 - 0.011 15.4 1.9 2.4 8.0 0.0 5.3 5 0 0 5 5 4 0 HAT (Half-A-TPR) repeat TPR_17 PF13431.1 KKK22147.1 - 0.013 15.6 5.4 1.8 8.9 0.0 6.0 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_1 PF00515.23 KKK22147.1 - 0.083 12.5 0.2 37 4.1 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat PfkB PF00294.19 KKK22152.1 - 1.7e-12 47.0 0.3 3e-12 46.2 0.2 1.2 1 1 0 1 1 1 1 pfkB family carbohydrate kinase DEAD PF00270.24 KKK22153.1 - 7.4e-40 136.2 0.4 1.6e-39 135.0 0.1 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KKK22153.1 - 1.6e-29 101.5 0.2 3.3e-29 100.5 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 KKK22153.1 - 0.0016 18.1 0.1 0.0039 16.9 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain ResIII PF04851.10 KKK22153.1 - 0.017 14.9 0.1 0.036 13.8 0.1 1.7 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.9 KKK22153.1 - 0.023 14.4 0.4 0.094 12.4 0.0 2.1 2 0 0 2 2 2 0 Flavivirus DEAD domain AAA_30 PF13604.1 KKK22153.1 - 0.024 14.2 0.3 0.056 13.0 0.2 1.6 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.1 KKK22153.1 - 0.083 13.0 0.7 0.38 10.9 0.5 2.0 1 1 0 1 1 1 0 AAA domain AAA_11 PF13086.1 KKK22153.1 - 0.14 11.6 0.2 0.19 11.2 0.2 1.5 1 1 0 1 1 1 0 AAA domain Aminotran_5 PF00266.14 KKK22154.1 - 4.7e-17 61.7 0.0 1.9e-12 46.6 0.0 2.3 2 0 0 2 2 2 2 Aminotransferase class-V MOSC_N PF03476.11 KKK22154.1 - 3.8e-06 26.6 0.0 8.7e-06 25.4 0.0 1.6 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain AAL_decarboxy PF03306.8 KKK22154.1 - 0.032 13.2 0.0 0.058 12.4 0.0 1.3 1 0 0 1 1 1 0 Alpha-acetolactate decarboxylase NMT1 PF09084.6 KKK22155.1 - 6.6e-78 261.2 0.0 8.3e-78 260.8 0.0 1.1 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.1 KKK22155.1 - 7.7e-09 35.3 1.4 0.028 13.7 0.0 3.2 2 1 0 3 3 3 3 NMT1-like family Phosphonate-bd PF12974.2 KKK22155.1 - 0.029 13.7 0.0 0.055 12.8 0.0 1.4 1 0 0 1 1 1 0 ABC transporter, phosphonate, periplasmic substrate-binding protein Glycogen_syn PF05693.8 KKK22156.1 - 0 1128.7 0.0 0 1128.4 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glyco_trans_4_4 PF13579.1 KKK22156.1 - 5.4e-07 29.8 0.2 1.1e-06 28.8 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glycos_transf_1 PF00534.15 KKK22156.1 - 3.8e-05 23.1 0.0 0.0012 18.3 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferases group 1 SnoaL PF07366.7 KKK22157.1 - 0.073 12.6 0.0 0.16 11.5 0.0 1.6 1 0 0 1 1 1 0 SnoaL-like polyketide cyclase CBF_beta PF02312.12 KKK22157.1 - 0.15 11.6 0.5 7.1 6.2 0.2 2.2 1 1 1 2 2 2 0 Core binding factor beta subunit APC8 PF04049.8 KKK22158.1 - 7.1e-47 158.7 0.1 5.2e-46 155.9 0.0 2.3 2 0 0 2 2 2 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_1 PF00515.23 KKK22158.1 - 4.5e-24 83.0 3.0 0.00015 21.2 0.0 7.8 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_11 PF13414.1 KKK22158.1 - 9e-20 70.1 16.0 3.5e-07 29.7 0.1 7.1 6 2 1 7 7 7 4 TPR repeat TPR_2 PF07719.12 KKK22158.1 - 5.3e-18 63.4 18.0 0.066 13.1 2.0 9.5 10 0 0 10 10 9 5 Tetratricopeptide repeat TPR_16 PF13432.1 KKK22158.1 - 1.5e-16 60.5 13.7 5.1e-05 23.8 0.0 7.5 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_8 PF13181.1 KKK22158.1 - 8.5e-16 56.4 8.5 0.00031 20.3 0.0 8.1 6 1 2 8 8 8 3 Tetratricopeptide repeat TPR_14 PF13428.1 KKK22158.1 - 1.6e-11 43.7 13.9 0.0056 17.2 0.0 9.4 8 2 2 10 10 10 2 Tetratricopeptide repeat Apc3 PF12895.2 KKK22158.1 - 3.6e-10 39.8 10.7 0.26 11.4 0.1 6.0 7 1 0 7 7 6 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 KKK22158.1 - 1.2e-09 37.8 6.5 0.00054 19.7 0.1 5.4 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.1 KKK22158.1 - 1.7e-09 37.8 8.9 0.7 10.2 0.0 7.3 7 1 0 7 7 7 3 Tetratricopeptide repeat TPR_17 PF13431.1 KKK22158.1 - 6.1e-08 32.2 6.4 2.2 8.6 0.0 7.7 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_12 PF13424.1 KKK22158.1 - 2e-06 27.6 28.4 0.032 14.1 1.6 7.7 7 2 3 10 10 10 3 Tetratricopeptide repeat TPR_15 PF13429.1 KKK22158.1 - 0.00093 18.3 2.9 0.00093 18.3 2.0 4.0 4 1 2 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.1 KKK22158.1 - 0.0012 18.4 13.6 7.1 6.6 0.0 6.8 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_6 PF13174.1 KKK22158.1 - 0.0012 19.1 24.9 37 5.0 0.2 10.2 10 1 0 10 10 10 0 Tetratricopeptide repeat TPR_10 PF13374.1 KKK22158.1 - 1.8 8.5 11.5 16 5.5 0.0 6.3 8 0 0 8 8 8 0 Tetratricopeptide repeat DNA_ligase_A_M PF01068.16 KKK22159.1 - 7.2e-20 71.2 0.0 1.3e-19 70.3 0.0 1.3 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 KKK22159.1 - 5.6e-11 42.5 0.0 1.1e-10 41.6 0.0 1.4 1 0 0 1 1 1 1 DNA ligase N terminus polyprenyl_synt PF00348.12 KKK22160.1 - 6.2e-71 238.2 0.0 7.3e-71 238.0 0.0 1.0 1 0 0 1 1 1 1 Polyprenyl synthetase Arylsulfotran_2 PF14269.1 KKK22161.1 - 3.3e-62 210.3 5.7 4.9e-62 209.7 4.0 1.3 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.6 KKK22161.1 - 3.3e-17 62.1 5.4 6.4e-17 61.2 3.7 1.4 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Vps54 PF07928.7 KKK22162.1 - 2.6e-48 163.5 0.1 6.3e-48 162.3 0.1 1.7 1 0 0 1 1 1 1 Vps54-like protein DUF2450 PF10475.4 KKK22162.1 - 3.2e-07 29.5 0.6 7.8e-07 28.2 0.4 1.6 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) LUC7 PF03194.10 KKK22162.1 - 0.054 13.0 2.4 0.05 13.1 0.4 1.8 2 0 0 2 2 2 0 LUC7 N_terminus MCM PF00493.18 KKK22163.1 - 2.2e-140 467.1 0.1 2.9e-140 466.8 0.0 1.1 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 KKK22163.1 - 2.7e-19 69.8 0.3 9.1e-19 68.1 0.2 1.9 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 KKK22163.1 - 5.5e-06 25.6 0.0 0.00071 18.7 0.0 2.3 1 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 KKK22163.1 - 4.6e-05 23.1 0.0 0.00011 21.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 KKK22163.1 - 0.0014 18.2 0.1 0.0053 16.3 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase_2 PF13335.1 KKK22163.1 - 0.034 14.5 0.3 0.12 12.7 0.2 1.9 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 KKK22163.1 - 0.063 12.7 0.0 1.4 8.3 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain DUF3449 PF11931.3 KKK22164.1 - 1.3e-70 236.9 0.9 3.3e-70 235.6 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3449) SF3a60_bindingd PF12108.3 KKK22164.1 - 3.6e-15 55.1 0.6 8.5e-15 53.9 0.4 1.7 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain zf-met PF12874.2 KKK22164.1 - 2.3e-09 37.1 2.4 9.6e-08 31.9 0.7 2.4 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KKK22164.1 - 7.8e-08 32.2 0.9 7.8e-08 32.2 0.6 2.5 2 1 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 KKK22164.1 - 0.00085 19.3 0.0 0.0071 16.4 0.0 2.4 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) Myb_CC_LHEQLE PF14379.1 KKK22164.1 - 0.045 13.3 7.1 23 4.6 4.9 3.1 1 1 0 1 1 1 0 MYB-CC type transfactor, LHEQLE motif zf-C2H2 PF00096.21 KKK22164.1 - 0.29 11.5 4.0 1.7 9.1 0.4 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KKK22164.1 - 0.34 11.3 2.8 17 6.0 0.2 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger DUF913 PF06025.7 KKK22167.1 - 1.5e-163 543.9 0.1 1.3e-162 540.8 0.0 2.8 3 0 0 3 3 3 1 Domain of Unknown Function (DUF913) DUF908 PF06012.7 KKK22167.1 - 2.1e-99 332.9 0.2 2.1e-99 332.9 0.2 2.7 2 0 0 2 2 2 1 Domain of Unknown Function (DUF908) HECT PF00632.20 KKK22167.1 - 1.1e-93 313.8 0.0 2e-93 313.0 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF4414 PF14377.1 KKK22167.1 - 1.4e-32 111.8 6.9 1.4e-32 111.8 4.8 3.5 2 1 0 2 2 2 1 Domain of unknown function (DUF4414) UBA PF00627.26 KKK22167.1 - 0.0067 16.2 0.1 0.025 14.4 0.1 2.1 1 0 0 1 1 1 1 UBA/TS-N domain Pribosyltran_N PF13793.1 KKK22168.1 - 3e-46 155.9 0.8 3.1e-44 149.4 0.0 2.5 2 0 0 2 2 2 2 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 KKK22168.1 - 3.9e-41 140.8 2.4 1.6e-34 119.3 0.8 2.4 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 KKK22168.1 - 9.7e-14 51.1 0.4 8.9e-13 48.0 0.3 2.2 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.1 KKK22168.1 - 8.6e-06 25.1 0.4 1.6e-05 24.2 0.2 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Chlorosome_CsmC PF11098.3 KKK22168.1 - 0.068 12.8 2.7 0.12 12.0 1.8 1.4 1 0 0 1 1 1 0 Chlorosome envelope protein C Kdo PF06293.9 KKK22179.1 - 2.6e-05 23.3 1.7 2.7e-05 23.3 0.0 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 KKK22179.1 - 0.00049 19.3 0.1 0.0013 17.9 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain APH PF01636.18 KKK22179.1 - 0.0024 17.6 0.1 0.0024 17.6 0.1 3.0 2 1 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KKK22179.1 - 0.036 13.6 0.0 0.036 13.6 0.0 2.0 2 0 0 2 2 2 0 Choline/ethanolamine kinase YrbL-PhoP_reg PF10707.4 KKK22179.1 - 0.044 13.1 0.0 0.044 13.1 0.0 2.3 2 1 0 2 2 2 0 PhoP regulatory network protein YrbL Synaptobrevin PF00957.16 KKK22179.1 - 0.21 11.2 4.0 0.5 10.0 2.4 1.8 1 1 1 2 2 2 0 Synaptobrevin Transposase_22 PF02994.9 KKK22179.1 - 0.26 9.7 13.0 0.49 8.8 9.0 1.4 1 0 0 1 1 1 0 L1 transposable element EMP24_GP25L PF01105.19 KKK22179.1 - 0.38 10.4 7.1 0.8 9.4 4.9 1.5 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD FUSC PF04632.7 KKK22179.1 - 4.4 5.6 11.2 9.2 4.5 7.7 1.5 1 0 0 1 1 1 0 Fusaric acid resistance protein family HSP70 PF00012.15 KKK22179.1 - 4.6 5.0 14.2 6.4 4.5 9.8 1.1 1 0 0 1 1 1 0 Hsp70 protein Atg14 PF10186.4 KKK22179.1 - 4.7 6.0 22.6 8.9 5.1 15.6 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 V_ATPase_I PF01496.14 KKK22179.1 - 7.9 4.1 12.2 11 3.7 8.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family APH PF01636.18 KKK22180.1 - 6.5e-06 26.0 0.1 1.4e-05 24.9 0.0 1.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KKK22180.1 - 1.3e-05 24.9 0.0 1.7e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 Choline/ethanolamine kinase TPR_11 PF13414.1 KKK22181.1 - 2.7e-44 148.6 26.3 1.6e-16 59.6 1.6 5.5 3 2 2 5 5 5 5 TPR repeat TPR_2 PF07719.12 KKK22181.1 - 2.7e-32 108.0 12.5 2.1e-05 24.0 0.0 7.8 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_1 PF00515.23 KKK22181.1 - 6e-32 107.9 12.5 1.1e-06 27.9 0.0 7.5 7 0 0 7 7 7 5 Tetratricopeptide repeat DnaJ PF00226.26 KKK22181.1 - 3.5e-27 93.9 2.9 1.2e-26 92.2 1.1 2.6 2 0 0 2 2 2 1 DnaJ domain TPR_16 PF13432.1 KKK22181.1 - 1.1e-26 92.8 16.4 4.3e-06 27.2 0.0 5.9 4 1 1 5 5 5 5 Tetratricopeptide repeat TPR_19 PF14559.1 KKK22181.1 - 2e-22 79.2 19.9 3.1e-07 30.6 0.4 5.7 5 1 1 6 6 5 4 Tetratricopeptide repeat TPR_8 PF13181.1 KKK22181.1 - 2.3e-15 55.1 5.7 0.017 14.8 0.0 7.3 6 1 0 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.1 KKK22181.1 - 3.5e-14 52.0 21.8 0.0037 17.7 0.1 8.0 6 2 3 9 9 7 3 Tetratricopeptide repeat TPR_7 PF13176.1 KKK22181.1 - 5e-13 47.7 3.3 0.037 13.8 0.0 6.8 6 0 0 6 6 6 3 Tetratricopeptide repeat Apc3 PF12895.2 KKK22181.1 - 1.2e-12 47.8 4.7 0.00026 21.0 0.0 3.9 3 1 1 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 KKK22181.1 - 1.2e-12 46.9 15.4 0.0081 16.2 0.3 6.7 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_6 PF13174.1 KKK22181.1 - 1e-10 41.3 10.9 0.041 14.3 0.0 7.6 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.1 KKK22181.1 - 2.8e-10 40.0 11.4 0.0094 15.8 0.2 5.4 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_9 PF13371.1 KKK22181.1 - 5.8e-09 35.6 10.6 0.038 13.8 0.1 4.6 4 1 1 5 5 5 3 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 KKK22181.1 - 4.3e-07 29.7 3.0 0.39 10.6 0.0 4.4 4 0 0 4 4 4 2 Fis1 C-terminal tetratricopeptide repeat BTAD PF03704.12 KKK22181.1 - 9.3e-06 26.0 4.5 0.057 13.7 0.0 4.0 3 1 0 3 3 3 2 Bacterial transcriptional activator domain TPR_15 PF13429.1 KKK22181.1 - 1.1e-05 24.6 5.3 1 8.3 0.0 4.7 3 2 1 4 4 4 2 Tetratricopeptide repeat TPR_20 PF14561.1 KKK22181.1 - 8.2e-05 22.6 5.6 2.2 8.4 0.2 4.6 3 2 1 4 4 4 1 Tetratricopeptide repeat SHNi-TPR PF10516.4 KKK22181.1 - 0.038 13.2 8.6 26 4.1 0.0 5.3 6 0 0 6 6 6 0 SHNi-TPR DUF2225 PF09986.4 KKK22181.1 - 0.065 12.6 0.1 1.8 7.9 0.0 2.6 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) TPR_4 PF07721.9 KKK22181.1 - 0.2 12.1 0.1 0.2 12.1 0.0 4.8 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_21 PF09976.4 KKK22181.1 - 0.21 11.5 0.1 0.21 11.5 0.1 4.7 3 2 2 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.1 KKK22181.1 - 0.55 10.2 10.7 9.3 6.3 0.0 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat MIT PF04212.13 KKK22181.1 - 0.68 9.8 4.3 2.6 7.9 0.1 3.3 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain Asp_Glu_race PF01177.17 KKK22200.1 - 4.5e-13 49.5 0.0 7.5e-13 48.8 0.0 1.4 1 1 0 1 1 1 1 Asp/Glu/Hydantoin racemase Aldo_ket_red PF00248.16 KKK22201.1 - 6.4e-55 185.9 0.0 7.3e-55 185.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family RBD PF02196.10 KKK22201.1 - 0.15 11.8 0.0 5.1 6.9 0.0 2.3 2 0 0 2 2 2 0 Raf-like Ras-binding domain Tubulin PF00091.20 KKK22202.1 - 1e-73 247.7 0.0 1.5e-73 247.2 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 KKK22202.1 - 2.9e-45 153.3 1.0 3.6e-45 153.0 0.1 1.6 2 0 0 2 2 2 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 KKK22202.1 - 6.4e-07 29.4 0.0 2.3e-06 27.6 0.0 2.0 2 0 0 2 2 2 1 Misato Segment II tubulin-like domain Pkinase PF00069.20 KKK22203.1 - 5.7e-11 42.0 0.0 9.8e-11 41.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK22203.1 - 8.4e-10 38.1 0.0 2.2e-09 36.8 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 KKK22203.1 - 8.3e-06 25.6 0.2 0.00029 20.6 0.2 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KKK22203.1 - 9.2e-05 22.1 0.7 0.11 12.1 0.0 2.4 1 1 1 2 2 2 2 Choline/ethanolamine kinase Kdo PF06293.9 KKK22203.1 - 0.0095 15.0 0.0 0.015 14.4 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1754 PF08555.5 KKK22204.1 - 5.1e-17 62.2 6.8 5.1e-17 62.2 4.7 1.5 2 0 0 2 2 2 1 Eukaryotic family of unknown function (DUF1754) Spt5_N PF11942.3 KKK22204.1 - 0.19 12.3 8.1 0.094 13.3 4.0 1.6 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal zf-AN1 PF01428.11 KKK22205.1 - 2.7e-11 43.1 12.6 3.9e-11 42.6 8.8 1.2 1 0 0 1 1 1 1 AN1-like Zinc finger DUF4187 PF13821.1 KKK22205.1 - 0.046 13.3 2.5 0.071 12.7 1.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4187) DUF202 PF02656.10 KKK22206.1 - 1.1e-25 89.6 0.9 1.1e-25 89.6 0.6 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF202) PTPA PF03095.10 KKK22207.1 - 9.8e-112 372.9 0.0 1.2e-111 372.7 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Reprolysin_5 PF13688.1 KKK22208.1 - 3e-31 108.8 1.6 3e-31 108.8 1.1 1.8 2 0 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.1 KKK22208.1 - 7.1e-29 100.8 0.2 7.1e-29 100.8 0.1 1.5 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 KKK22208.1 - 5.3e-14 52.6 0.3 5.3e-14 52.6 0.2 1.7 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 KKK22208.1 - 1.3e-12 48.3 0.6 9.4e-12 45.5 0.0 2.4 2 1 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin PF01421.14 KKK22208.1 - 6.8e-05 22.5 0.2 0.00056 19.5 0.1 2.2 1 1 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Pep_M12B_propep PF01562.14 KKK22208.1 - 0.0017 18.1 0.0 0.072 12.8 0.0 2.2 2 0 0 2 2 2 1 Reprolysin family propeptide HxxPF_rpt PF13745.1 KKK22208.1 - 0.0021 18.3 0.0 0.42 10.9 0.0 3.1 3 0 0 3 3 3 1 HxxPF-repeated domain Actin PF00022.14 KKK22209.1 - 3.9e-93 311.9 0.0 1.1e-81 274.3 0.0 2.0 2 0 0 2 2 2 2 Actin MreB_Mbl PF06723.8 KKK22209.1 - 0.12 10.9 0.0 0.4 9.2 0.0 1.7 1 1 0 1 1 1 0 MreB/Mbl protein DUF3425 PF11905.3 KKK22210.1 - 2.6e-37 127.7 3.1 4.8e-37 126.8 2.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 KKK22210.1 - 0.0011 18.8 9.4 0.0063 16.4 4.6 2.3 1 1 1 2 2 2 1 bZIP transcription factor DUF904 PF06005.7 KKK22210.1 - 0.26 11.5 4.5 0.48 10.7 3.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF904) bZIP_2 PF07716.10 KKK22210.1 - 0.34 10.7 12.3 2.4 8.0 8.5 2.1 1 1 0 1 1 1 0 Basic region leucine zipper NAD_binding_2 PF03446.10 KKK22211.1 - 3.7e-29 101.6 0.2 5.3e-29 101.1 0.1 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 KKK22211.1 - 4.2e-11 42.9 0.0 8e-11 42.0 0.0 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.12 KKK22211.1 - 0.0002 21.7 0.0 0.00083 19.7 0.0 2.1 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent DUF1325 PF07039.6 KKK22212.1 - 1.5e-30 105.4 0.0 2.3e-30 104.8 0.0 1.3 1 0 0 1 1 1 1 SGF29 tudor-like domain TUDOR PF00567.19 KKK22212.1 - 0.16 11.7 0.0 1.6 8.5 0.0 2.3 2 0 0 2 2 2 0 Tudor domain GTP_cyclohydro2 PF00925.15 KKK22213.1 - 9.4e-57 190.9 0.0 3.6e-52 175.9 0.0 2.1 2 0 0 2 2 2 2 GTP cyclohydrolase II Coatomer_E PF04733.9 KKK22214.1 - 2.3e-38 132.0 0.5 2.6e-38 131.8 0.4 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_19 PF14559.1 KKK22214.1 - 9.5e-06 25.8 4.3 0.00042 20.6 0.2 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 KKK22214.1 - 2.9e-05 24.3 4.1 0.00045 20.6 0.1 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 KKK22214.1 - 0.00038 21.0 10.1 0.0049 17.5 0.6 3.1 2 1 3 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.12 KKK22214.1 - 0.002 17.8 3.1 0.024 14.5 0.1 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 KKK22214.1 - 0.003 17.1 0.3 0.05 13.2 0.0 2.5 2 1 0 2 2 2 1 TPR repeat TPR_1 PF00515.23 KKK22214.1 - 0.02 14.4 0.1 0.15 11.7 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.1 KKK22214.1 - 0.025 14.4 1.7 2.1 8.2 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Sigma70_r3 PF04539.11 KKK22214.1 - 0.33 10.8 2.3 4.6 7.1 0.8 2.8 2 1 0 2 2 2 0 Sigma-70 region 3 TPR_4 PF07721.9 KKK22214.1 - 1.3 9.6 5.8 0.86 10.2 0.4 3.1 3 1 1 4 4 4 0 Tetratricopeptide repeat PMI_typeI PF01238.16 KKK22215.1 - 6.9e-149 495.8 0.0 8e-149 495.6 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I Cupin_2 PF07883.6 KKK22215.1 - 0.02 14.3 0.1 0.39 10.2 0.0 2.2 2 0 0 2 2 2 0 Cupin domain AraC_binding PF02311.14 KKK22215.1 - 0.057 13.1 0.0 15 5.2 0.0 2.9 3 0 0 3 3 3 0 AraC-like ligand binding domain EamA PF00892.15 KKK22216.1 - 5.8e-13 48.9 25.9 4.4e-07 29.9 12.6 2.5 2 0 0 2 2 2 2 EamA-like transporter family Metallophos PF00149.23 KKK22216.1 - 2.5e-08 33.5 0.4 1.8e-07 30.7 0.3 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase EmrE PF13536.1 KKK22216.1 - 1.2e-06 28.7 16.3 9.6e-05 22.5 0.0 2.6 2 0 0 2 2 2 2 Multidrug resistance efflux transporter Metallophos_2 PF12850.2 KKK22216.1 - 6.6e-06 26.0 0.0 1.4e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain UAA PF08449.6 KKK22216.1 - 0.0005 19.0 1.1 0.0005 19.0 0.8 1.5 1 1 0 1 1 1 1 UAA transporter family Nuc_sug_transp PF04142.10 KKK22216.1 - 0.0023 17.0 0.0 0.0059 15.7 0.0 1.6 1 0 0 1 1 1 1 Nucleotide-sugar transporter TPT PF03151.11 KKK22216.1 - 0.043 13.4 18.3 0.083 12.5 6.1 2.8 3 0 0 3 3 3 0 Triose-phosphate Transporter family DUF202 PF02656.10 KKK22216.1 - 0.15 12.3 12.0 0.63 10.3 3.4 4.2 3 2 0 3 3 3 0 Domain of unknown function (DUF202) Pkinase PF00069.20 KKK22217.1 - 3.6e-20 72.2 0.0 8.4e-20 71.0 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK22217.1 - 0.00038 19.6 0.1 0.00091 18.3 0.1 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Ribosomal_S30 PF04758.9 KKK22231.1 - 1.5e-19 69.5 7.5 1.7e-19 69.3 5.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 GATA PF00320.22 KKK22240.1 - 4e-16 58.0 2.4 7.2e-16 57.2 1.7 1.4 1 0 0 1 1 1 1 GATA zinc finger TF_Zn_Ribbon PF08271.7 KKK22240.1 - 0.024 13.9 0.2 0.045 13.0 0.2 1.4 1 0 0 1 1 1 0 TFIIB zinc-binding YscO PF07321.7 KKK22240.1 - 0.035 13.9 4.9 0.051 13.4 3.4 1.3 1 0 0 1 1 1 0 Type III secretion protein YscO GAS PF13851.1 KKK22240.1 - 0.046 12.9 1.0 0.07 12.3 0.7 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DivIVA PF05103.8 KKK22240.1 - 0.071 13.1 3.8 0.24 11.4 2.6 1.7 1 1 0 1 1 1 0 DivIVA protein ArfGap PF01412.13 KKK22240.1 - 0.077 12.7 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Putative GTPase activating protein for Arf eIF-5_eIF-2B PF01873.12 KKK22240.1 - 0.18 11.4 0.2 0.32 10.6 0.2 1.4 1 0 0 1 1 1 0 Domain found in IF2B/IF5 CENP-F_leu_zip PF10473.4 KKK22240.1 - 0.22 11.3 5.2 11 5.9 0.0 2.2 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Pox_A_type_inc PF04508.7 KKK22240.1 - 0.57 10.1 5.8 2.2 8.3 1.0 3.2 2 1 0 2 2 2 0 Viral A-type inclusion protein repeat WD40_alt PF14077.1 KKK22240.1 - 1.7 8.3 4.4 24 4.6 0.0 3.1 3 0 0 3 3 3 0 Alternative WD40 repeat motif APH PF01636.18 KKK22259.1 - 2.5e-12 47.0 0.0 1.4e-11 44.6 0.0 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KKK22259.1 - 0.037 13.5 2.9 0.062 12.8 0.1 2.1 2 0 0 2 2 2 0 Choline/ethanolamine kinase CPL PF08144.6 KKK22297.1 - 4.9e-16 58.8 1.2 4.9e-15 55.6 0.1 3.0 2 1 0 2 2 2 1 CPL (NUC119) domain Daxx PF03344.10 KKK22297.1 - 0.00013 20.6 16.2 0.00013 20.6 11.2 2.0 2 0 0 2 2 2 1 Daxx Family Nop14 PF04147.7 KKK22297.1 - 0.013 13.4 22.5 0.021 12.7 15.6 1.3 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.5 KKK22297.1 - 1.4 7.9 33.4 3.1 6.7 23.1 1.6 1 0 0 1 1 1 0 BUD22 DUF2457 PF10446.4 KKK22297.1 - 1.6 7.3 29.1 2.8 6.5 20.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Rad51 PF08423.6 KKK22298.1 - 3.2e-138 458.7 0.0 4.5e-138 458.3 0.0 1.2 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 KKK22298.1 - 1.1e-13 51.0 0.0 1.9e-13 50.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain RecA PF00154.16 KKK22298.1 - 5.3e-08 32.2 0.0 7.8e-08 31.7 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein HHH_5 PF14520.1 KKK22298.1 - 6.5e-07 29.4 0.1 1.6e-06 28.2 0.1 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain KaiC PF06745.8 KKK22298.1 - 1.4e-05 24.3 0.2 4.1e-05 22.8 0.1 1.8 1 1 0 1 1 1 1 KaiC PAXNEB PF05625.6 KKK22298.1 - 0.048 12.5 0.1 0.11 11.3 0.0 1.5 1 0 0 1 1 1 0 PAXNEB protein DnaB_C PF03796.10 KKK22298.1 - 0.05 12.4 0.0 0.1 11.4 0.0 1.4 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain ABC_tran PF00005.22 KKK22299.1 - 2.5e-34 118.5 0.0 8.1e-16 58.5 0.0 3.6 3 0 0 3 3 3 3 ABC transporter ABC_membrane PF00664.18 KKK22299.1 - 2.1e-25 89.6 23.9 1.1e-21 77.4 4.0 2.6 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.14 KKK22299.1 - 2e-07 30.4 0.5 0.00087 18.5 0.0 3.1 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 KKK22299.1 - 2.1e-06 27.8 0.1 0.0013 18.7 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.1 KKK22299.1 - 2.1e-06 27.9 0.2 0.058 13.3 0.0 2.9 2 1 0 2 2 2 2 AAA domain DUF258 PF03193.11 KKK22299.1 - 0.00026 20.2 0.1 0.00099 18.3 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 KKK22299.1 - 0.00079 18.9 0.0 0.0024 17.3 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA PF00004.24 KKK22299.1 - 0.001 19.2 0.7 0.024 14.8 0.0 3.2 4 0 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 KKK22299.1 - 0.0013 18.8 0.1 0.2 11.8 0.0 3.1 2 1 1 3 3 2 1 RNA helicase AAA_33 PF13671.1 KKK22299.1 - 0.004 17.0 0.0 0.032 14.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 KKK22299.1 - 0.0053 16.9 0.8 0.18 11.9 0.0 2.7 2 1 0 2 2 2 1 AAA domain SbcCD_C PF13558.1 KKK22299.1 - 0.011 15.6 0.0 3.3 7.6 0.0 2.7 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Miro PF08477.8 KKK22299.1 - 0.014 15.9 0.1 4.1 7.9 0.0 3.0 3 0 0 3 3 2 0 Miro-like protein AAA_25 PF13481.1 KKK22299.1 - 0.014 14.7 0.0 0.035 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 KKK22299.1 - 0.016 15.1 0.0 0.074 13.0 0.0 2.1 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_23 PF13476.1 KKK22299.1 - 0.022 15.0 0.2 0.043 14.1 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 KKK22299.1 - 0.039 13.3 0.2 0.17 11.3 0.1 1.9 2 0 0 2 2 2 0 AAA-like domain MobB PF03205.9 KKK22299.1 - 0.09 12.4 0.2 1.2 8.8 0.0 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_30 PF13604.1 KKK22299.1 - 0.17 11.4 0.2 5.6 6.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 KKK22299.1 - 0.21 12.4 0.1 0.73 10.6 0.1 1.9 1 0 0 1 1 1 0 AAA domain Nup160 PF11715.3 KKK22300.1 - 9.8e-174 578.4 2.1 1.5e-173 577.9 1.4 1.3 1 0 0 1 1 1 1 Nucleoporin Nup120/160 TPR_12 PF13424.1 KKK22300.1 - 3 7.8 8.4 8.7 6.3 0.2 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat MFS_1 PF07690.11 KKK22301.1 - 9.9e-36 123.1 43.0 9.9e-36 123.1 29.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KKK22301.1 - 0.00013 20.3 2.6 0.00013 20.3 1.8 2.2 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) AMP-binding PF00501.23 KKK22302.1 - 6.8e-302 999.7 0.0 3.3e-85 286.0 0.0 4.2 4 0 0 4 4 4 4 AMP-binding enzyme Condensation PF00668.15 KKK22302.1 - 5.1e-247 816.8 0.6 3.3e-52 177.2 0.0 10.0 9 1 0 9 9 9 8 Condensation domain PP-binding PF00550.20 KKK22302.1 - 6.6e-48 160.8 0.0 3.7e-11 43.1 0.0 5.8 5 0 0 5 5 5 5 Phosphopantetheine attachment site AMP-binding_C PF13193.1 KKK22302.1 - 5.3e-12 46.5 0.0 0.0032 18.3 0.0 4.8 4 0 0 4 4 4 2 AMP-binding enzyme C-terminal domain AATase PF07247.7 KKK22302.1 - 0.0029 16.2 0.0 4.9 5.5 0.0 3.6 3 0 0 3 3 3 1 Alcohol acetyltransferase SopA PF13981.1 KKK22302.1 - 0.0072 16.3 0.0 0.041 13.9 0.0 2.3 2 0 0 2 2 2 1 SopA-like central domain HxxPF_rpt PF13745.1 KKK22302.1 - 0.21 11.9 2.2 4.8 7.5 0.0 4.0 5 0 0 5 5 5 0 HxxPF-repeated domain SbcD_C PF12320.3 KKK22302.1 - 0.52 10.3 0.4 44 4.1 0.1 3.5 4 0 0 4 4 4 0 Type 5 capsule protein repressor C-terminal domain TOM13 PF08219.6 KKK22305.1 - 2.9e-31 107.0 0.0 3.6e-31 106.7 0.0 1.1 1 0 0 1 1 1 1 Outer membrane protein TOM13 60KD_IMP PF02096.15 KKK22306.1 - 3.7e-40 137.7 0.1 6.6e-40 136.9 0.1 1.4 1 0 0 1 1 1 1 60Kd inner membrane protein COG2 PF06148.6 KKK22308.1 - 1.2e-36 125.5 3.6 1.2e-36 125.5 2.5 1.8 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 Vps51 PF08700.6 KKK22308.1 - 6.5e-06 25.8 2.5 5.5e-05 22.9 1.7 2.5 1 1 0 1 1 1 1 Vps51/Vps67 COG5 PF10392.4 KKK22308.1 - 9.6e-06 25.5 1.5 9.6e-06 25.5 1.0 2.1 2 0 0 2 2 2 1 Golgi transport complex subunit 5 DUF2450 PF10475.4 KKK22308.1 - 0.0012 17.8 0.4 0.0019 17.1 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) Bul1_C PF04426.7 KKK22308.1 - 0.045 12.9 0.3 0.09 11.9 0.1 1.5 1 1 0 1 1 1 0 Bul1 C terminus Sec34 PF04136.10 KKK22308.1 - 0.066 12.9 2.3 0.18 11.5 0.3 2.2 1 1 1 2 2 2 0 Sec34-like family FlaC_arch PF05377.6 KKK22308.1 - 0.23 11.3 7.9 4.4 7.2 0.3 3.7 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) Reo_sigmaC PF04582.7 KKK22308.1 - 0.27 10.3 2.3 0.24 10.5 0.2 1.9 2 0 0 2 2 2 0 Reovirus sigma C capsid protein Spc7 PF08317.6 KKK22308.1 - 0.87 8.1 9.2 0.062 11.9 2.3 1.9 2 0 0 2 2 2 0 Spc7 kinetochore protein NPV_P10 PF05531.7 KKK22308.1 - 1.5 9.1 5.0 4.4 7.6 0.6 2.9 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF1090 PF06476.7 KKK22308.1 - 2.2 7.9 7.4 3.4 7.3 0.4 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1090) V_ATPase_I PF01496.14 KKK22308.1 - 2.2 6.0 4.3 1.9 6.2 2.4 1.2 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family TBPIP PF07106.8 KKK22308.1 - 2.6 7.5 7.7 2.1 7.8 1.5 2.4 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) IncA PF04156.9 KKK22308.1 - 7.2 6.1 18.9 0.21 11.1 7.5 2.2 1 1 1 2 2 2 0 IncA protein APG6 PF04111.7 KKK22308.1 - 10 5.0 8.9 0.61 9.0 2.3 1.6 2 0 0 2 2 2 0 Autophagy protein Apg6 SEP PF08059.8 KKK22309.1 - 8.6e-29 99.6 0.1 1.7e-28 98.7 0.0 1.5 1 0 0 1 1 1 1 SEP domain UBX PF00789.15 KKK22309.1 - 1.3e-15 57.2 0.0 2.2e-15 56.4 0.0 1.4 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.1 KKK22309.1 - 6.1e-13 48.0 1.8 1e-12 47.3 1.3 1.4 1 0 0 1 1 1 1 UBA-like domain ParA PF10609.4 KKK22310.1 - 7.7e-33 112.2 0.1 7.7e-33 112.2 0.1 1.9 2 0 0 2 2 2 1 ParA/MinD ATPase like CbiA PF01656.18 KKK22310.1 - 1.6e-11 44.0 0.0 3.1e-11 43.0 0.0 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.6 KKK22310.1 - 1.2e-07 31.0 0.0 2.3e-06 26.8 0.0 2.0 2 0 0 2 2 2 1 ATPase MipZ AAA_31 PF13614.1 KKK22310.1 - 3.7e-05 23.7 0.1 0.00018 21.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain ArsA_ATPase PF02374.10 KKK22310.1 - 0.0007 18.7 1.3 0.0013 17.8 0.9 1.3 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_25 PF13481.1 KKK22310.1 - 0.00072 19.0 0.1 0.0013 18.2 0.1 1.3 1 0 0 1 1 1 1 AAA domain ArgK PF03308.11 KKK22310.1 - 0.0072 15.1 0.3 0.01 14.6 0.2 1.2 1 0 0 1 1 1 1 ArgK protein YhjQ PF06564.7 KKK22310.1 - 0.0086 15.4 0.3 0.025 13.9 0.1 1.8 2 0 0 2 2 2 1 YhjQ protein AAA_26 PF13500.1 KKK22310.1 - 0.045 13.3 0.6 0.65 9.5 0.4 2.3 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.15 KKK22310.1 - 0.074 12.7 0.1 0.12 12.0 0.1 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase DUF258 PF03193.11 KKK22310.1 - 0.16 11.1 1.0 0.26 10.4 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Guanylate_kin PF00625.16 KKK22334.1 - 1.3e-49 168.1 0.1 1.6e-49 167.8 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase DUF1895 PF08988.5 KKK22334.1 - 0.029 14.3 0.1 0.07 13.1 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1895) DUF2183 PF09949.4 KKK22342.1 - 1.2e-30 105.3 0.1 2.3e-30 104.4 0.1 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) LNS2 PF08235.8 KKK22342.1 - 0.005 16.4 0.0 0.0077 15.8 0.0 1.3 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) GPP34 PF05719.6 KKK22343.1 - 7e-43 147.0 0.2 8.5e-43 146.8 0.1 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) VHS PF00790.14 KKK22345.1 - 5.9e-34 116.7 1.2 1.4e-32 112.2 0.2 2.9 2 1 0 2 2 2 1 VHS domain GAT PF03127.9 KKK22345.1 - 3.2e-25 88.0 0.3 8.6e-25 86.6 0.2 1.8 1 0 0 1 1 1 1 GAT domain Alpha_adaptinC2 PF02883.15 KKK22345.1 - 5.5e-22 78.2 0.1 1.1e-21 77.3 0.0 1.4 1 0 0 1 1 1 1 Adaptin C-terminal domain Mei5 PF10376.4 KKK22345.1 - 0.0095 15.4 1.5 0.022 14.2 1.1 1.6 1 0 0 1 1 1 1 Double-strand recombination repair protein DUF935 PF06074.7 KKK22345.1 - 1 7.9 6.3 1.6 7.3 4.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF935) CBS PF00571.23 KKK22347.1 - 3.8e-24 84.1 4.8 8.8e-07 28.6 0.1 5.3 5 0 0 5 5 5 5 CBS domain Mcp5_PH PF12814.2 KKK22360.1 - 1.3e-48 163.9 0.0 3e-48 162.8 0.0 1.6 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology TPR_MLP1_2 PF07926.7 KKK22360.1 - 0.016 14.9 14.2 0.087 12.5 3.9 2.4 1 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein IncA PF04156.9 KKK22360.1 - 0.05 13.1 9.1 0.14 11.7 6.3 1.7 1 0 0 1 1 1 0 IncA protein Lebercilin PF15619.1 KKK22360.1 - 0.055 12.8 11.8 0.11 11.9 8.2 1.4 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease HAUS-augmin3 PF14932.1 KKK22360.1 - 0.17 11.0 7.3 0.29 10.2 5.0 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 Fib_alpha PF08702.5 KKK22360.1 - 0.55 10.3 1.8 7.7 6.6 0.2 2.3 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family APG6 PF04111.7 KKK22360.1 - 0.56 9.1 8.2 0.99 8.3 5.7 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 TMF_DNA_bd PF12329.3 KKK22360.1 - 1.1 9.0 12.6 0.77 9.6 1.0 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding GAS PF13851.1 KKK22360.1 - 1.2 8.3 14.8 0.96 8.6 1.7 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding ADIP PF11559.3 KKK22360.1 - 4.8 7.0 17.4 0.36 10.7 2.9 2.3 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Reo_sigmaC PF04582.7 KKK22360.1 - 8.8 5.4 7.7 10 5.1 2.0 2.2 2 0 0 2 2 2 0 Reovirus sigma C capsid protein Atg14 PF10186.4 KKK22360.1 - 9.9 5.0 14.3 9.5 5.0 8.5 1.9 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Methyltransf_23 PF13489.1 KKK22370.1 - 7.7e-10 38.7 0.0 1.1e-09 38.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KKK22370.1 - 4.5e-07 29.5 0.0 6.9e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KKK22370.1 - 4.4e-06 27.0 0.0 8.5e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KKK22370.1 - 0.00055 20.3 0.0 0.00093 19.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KKK22370.1 - 0.0057 15.7 0.0 0.0084 15.2 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 KKK22370.1 - 0.024 15.2 0.0 0.08 13.5 0.0 1.9 2 1 0 2 2 2 0 Methyltransferase domain Aminotran_1_2 PF00155.16 KKK22371.1 - 4.5e-40 137.7 0.0 5.5e-40 137.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 KKK22371.1 - 0.0036 16.4 0.0 0.0053 15.9 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DUF4585 PF15232.1 KKK22371.1 - 0.036 13.9 0.1 0.075 12.8 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4585) Trp_DMAT PF11991.3 KKK22372.1 - 4.2e-88 295.9 0.0 5.2e-88 295.6 0.0 1.1 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase p450 PF00067.17 KKK22373.1 - 2.7e-43 148.1 0.0 4e-43 147.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 GST_N_3 PF13417.1 KKK22374.1 - 1.4e-06 28.4 0.0 3.5e-06 27.1 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KKK22374.1 - 2.4e-06 27.4 0.0 4.2e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 KKK22374.1 - 5.6e-05 23.0 0.0 0.00012 21.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KKK22374.1 - 0.0002 21.2 0.1 0.00055 19.7 0.0 1.7 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KKK22374.1 - 0.011 16.1 0.0 0.025 15.0 0.0 1.5 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain PAP2 PF01569.16 KKK22375.1 - 9.6e-15 54.3 5.2 9.6e-15 54.3 3.6 2.3 2 1 1 3 3 3 1 PAP2 superfamily PAP2_3 PF14378.1 KKK22375.1 - 2e-06 27.4 7.0 2e-06 27.4 4.9 1.9 2 1 0 2 2 2 1 PAP2 superfamily Methyltransf_23 PF13489.1 KKK22376.1 - 7.7e-10 38.7 0.0 1.1e-09 38.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KKK22376.1 - 0.02 15.3 0.0 0.035 14.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 KKK22376.1 - 0.02 14.4 0.0 1.3 8.5 0.0 2.5 3 1 0 3 3 3 0 Methyltransferase domain Methyltransf_11 PF08241.7 KKK22376.1 - 0.022 15.2 0.0 0.038 14.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Pyr_redox_2 PF07992.9 KKK22377.1 - 1.1e-14 54.7 0.0 2.5e-14 53.6 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KKK22377.1 - 5.8e-06 25.3 0.5 1.1e-05 24.4 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.1 KKK22377.1 - 1.7e-05 24.9 0.2 0.00052 20.1 0.1 2.3 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KKK22377.1 - 2.5e-05 22.9 0.3 0.0011 17.5 0.1 2.2 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.1 KKK22377.1 - 7.3e-05 22.7 0.0 0.00017 21.5 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 KKK22377.1 - 0.00013 21.7 0.0 0.075 12.8 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 KKK22377.1 - 0.00036 19.7 0.0 0.0006 18.9 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 KKK22377.1 - 0.0009 18.3 0.0 0.0018 17.3 0.0 1.4 1 0 0 1 1 1 1 Thi4 family DAO PF01266.19 KKK22377.1 - 0.0012 17.7 0.2 0.0032 16.4 0.1 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 KKK22377.1 - 0.0015 17.4 0.3 0.1 11.4 0.0 2.9 3 0 0 3 3 3 1 Glucose inhibited division protein A K_oxygenase PF13434.1 KKK22377.1 - 0.0066 15.4 0.1 2.2 7.1 0.0 2.2 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.7 KKK22377.1 - 0.096 11.5 0.1 0.17 10.7 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_oxidored PF12831.2 KKK22377.1 - 0.12 11.3 0.4 0.17 10.9 0.3 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase UBX PF00789.15 KKK22377.1 - 0.13 12.3 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 UBX domain AMP-binding PF00501.23 KKK22378.1 - 4.8e-150 499.5 0.0 5.3e-82 275.4 0.0 3.2 2 1 1 3 3 3 3 AMP-binding enzyme Condensation PF00668.15 KKK22378.1 - 1.6e-64 217.6 0.0 2.1e-39 135.1 0.0 3.0 2 1 0 2 2 2 2 Condensation domain PP-binding PF00550.20 KKK22378.1 - 1.7e-15 57.0 0.1 2.3e-07 30.9 0.0 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding_C PF13193.1 KKK22378.1 - 3.9e-13 50.1 1.7 4.1e-07 30.8 0.3 2.8 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain HxxPF_rpt PF13745.1 KKK22378.1 - 8.7e-11 41.9 0.0 9.8e-07 29.0 0.0 3.5 3 0 0 3 3 3 2 HxxPF-repeated domain DUF3632 PF12311.3 KKK22379.1 - 2.4e-39 135.0 0.0 3.4e-39 134.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) Carot_N PF09150.5 KKK22379.1 - 0.085 12.5 0.0 11 5.6 0.0 2.9 3 0 0 3 3 3 0 Orange carotenoid protein, N-terminal Bradykinin PF06753.7 KKK22379.1 - 0.29 10.6 3.4 0.12 11.8 0.5 1.7 2 0 0 2 2 2 0 Bradykinin ketoacyl-synt PF00109.21 KKK22380.1 - 1.1e-71 241.3 0.0 1.1e-71 241.3 0.0 2.5 3 0 0 3 3 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 KKK22380.1 - 2.4e-63 214.3 0.0 5.1e-63 213.3 0.0 1.6 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 KKK22380.1 - 3.3e-40 138.0 1.3 6.8e-40 137.0 0.9 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.17 KKK22380.1 - 2e-34 117.9 0.1 8.7e-34 115.9 0.0 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.5 KKK22380.1 - 1.1e-30 106.6 0.1 2.6e-30 105.4 0.0 1.7 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 KKK22380.1 - 4.7e-18 65.6 0.2 6.1e-17 62.0 0.0 2.6 2 0 0 2 2 2 1 short chain dehydrogenase Methyltransf_12 PF08242.7 KKK22380.1 - 4.9e-17 62.2 0.0 1.2e-16 61.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KKK22380.1 - 4.7e-10 39.4 0.0 1.2e-09 38.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KKK22380.1 - 7.1e-08 33.0 0.0 4.1e-07 30.5 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 KKK22380.1 - 6.5e-07 29.7 0.0 2e-06 28.2 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KKK22380.1 - 4.8e-06 26.2 0.0 9.1e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 KKK22380.1 - 1.4e-05 25.2 0.3 3.4e-05 24.0 0.2 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 KKK22380.1 - 0.0078 15.2 0.1 0.0078 15.2 0.1 1.7 2 0 0 2 2 2 1 Thiolase, N-terminal domain Methyltransf_25 PF13649.1 KKK22380.1 - 0.0091 16.3 0.0 0.03 14.6 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KKK22380.1 - 0.0098 15.0 0.0 0.018 14.1 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family ADH_zinc_N_2 PF13602.1 KKK22380.1 - 0.012 16.5 0.4 4.4 8.2 0.0 3.6 4 0 0 4 4 2 0 Zinc-binding dehydrogenase ACP_syn_III PF08545.5 KKK22380.1 - 0.021 14.4 1.3 0.08 12.6 0.5 2.3 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Methyltransf_16 PF10294.4 KKK22380.1 - 0.52 9.7 0.0 1.1 8.7 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase CMD PF02627.15 KKK22381.1 - 0.0045 16.8 7.2 0.13 12.1 0.2 3.4 3 2 0 3 3 3 2 Carboxymuconolactone decarboxylase family MFS_1 PF07690.11 KKK22382.1 - 1.5e-40 139.0 65.1 5.9e-32 110.7 26.1 3.5 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KKK22382.1 - 5.7e-24 84.2 20.5 7.4e-24 83.8 14.2 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 KKK22382.1 - 6.6e-13 48.0 14.9 6.6e-13 48.0 10.3 3.0 3 1 0 3 3 3 2 Sugar (and other) transporter CBM_4_9 PF02018.12 KKK22383.1 - 6.3e-10 39.1 3.4 1.9e-09 37.6 2.3 1.9 1 0 0 1 1 1 1 Carbohydrate binding domain FAD_binding_3 PF01494.14 KKK22384.1 - 1.8e-25 89.7 7.5 3.7e-23 82.1 5.2 3.0 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 KKK22384.1 - 2.5e-06 26.6 0.0 0.0017 17.3 0.0 2.5 3 0 0 3 3 3 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KKK22384.1 - 0.00033 19.6 0.2 0.00033 19.6 0.2 2.0 3 0 0 3 3 3 1 FAD binding domain NAD_binding_8 PF13450.1 KKK22384.1 - 0.0015 18.5 0.2 0.0048 16.8 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 KKK22384.1 - 0.0015 18.6 0.1 0.013 15.5 0.0 2.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KKK22384.1 - 0.007 15.4 0.0 0.012 14.7 0.0 1.3 1 0 0 1 1 1 1 Thi4 family ThiF PF00899.16 KKK22384.1 - 0.12 12.2 0.7 0.25 11.1 0.5 1.5 1 0 0 1 1 1 0 ThiF family Pyr_redox PF00070.22 KKK22384.1 - 0.14 12.5 0.1 0.99 9.8 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KKK22385.1 - 7.9e-18 65.2 0.0 1.1e-14 55.0 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KKK22385.1 - 2.3e-14 53.1 0.2 2.4e-10 40.2 0.0 3.5 3 1 1 4 4 4 2 NAD(P)-binding Rossmann-like domain FMO-like PF00743.14 KKK22385.1 - 4.2e-11 41.7 0.0 2e-07 29.6 0.0 2.4 3 0 0 3 3 3 2 Flavin-binding monooxygenase-like Pyr_redox PF00070.22 KKK22385.1 - 5.5e-08 33.0 0.5 0.0071 16.7 0.0 3.2 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KKK22385.1 - 9.3e-08 32.1 0.0 3.2e-05 23.8 0.0 3.1 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KKK22385.1 - 1.7e-06 27.3 0.0 0.00099 18.2 0.0 2.2 2 0 0 2 2 2 2 Thi4 family K_oxygenase PF13434.1 KKK22385.1 - 1.9e-06 27.0 0.0 0.00032 19.7 0.0 2.4 3 0 0 3 3 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 KKK22385.1 - 4e-06 26.6 0.4 0.013 15.3 0.0 3.4 3 0 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.19 KKK22385.1 - 1.4e-05 24.1 1.1 5.5e-05 22.2 0.0 2.4 4 0 0 4 4 4 1 FAD dependent oxidoreductase HI0933_like PF03486.9 KKK22385.1 - 3.2e-05 22.5 0.5 0.063 11.7 0.0 2.4 3 0 0 3 3 3 2 HI0933-like protein FAD_binding_3 PF01494.14 KKK22385.1 - 0.00035 19.7 0.1 0.0089 15.1 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain FAD_binding_2 PF00890.19 KKK22385.1 - 0.00052 18.9 0.0 0.0044 15.9 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain 2-Hacid_dh_C PF02826.14 KKK22385.1 - 0.00084 18.5 0.0 0.025 13.7 0.0 2.4 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 KKK22385.1 - 0.0033 17.4 0.0 0.096 12.6 0.0 2.4 2 0 0 2 2 2 1 NADH(P)-binding Lycopene_cycl PF05834.7 KKK22385.1 - 0.011 14.7 0.0 0.45 9.3 0.0 2.4 3 0 0 3 3 3 0 Lycopene cyclase protein ApbA PF02558.11 KKK22385.1 - 0.019 14.4 0.6 2.9 7.3 0.2 2.4 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA adh_short PF00106.20 KKK22385.1 - 0.046 13.6 0.1 0.16 11.8 0.0 1.9 2 0 0 2 2 2 0 short chain dehydrogenase NAD_binding_7 PF13241.1 KKK22385.1 - 0.046 13.9 0.0 12 6.2 0.0 2.6 2 0 0 2 2 2 0 Putative NAD(P)-binding CPSase_L_chain PF00289.17 KKK22385.1 - 0.066 13.3 0.0 7.1 6.7 0.0 2.5 2 0 0 2 2 2 0 Carbamoyl-phosphate synthase L chain, N-terminal domain HK PF02110.10 KKK22385.1 - 0.12 11.5 0.1 0.19 10.8 0.1 1.2 1 0 0 1 1 1 0 Hydroxyethylthiazole kinase family TrkA_N PF02254.13 KKK22385.1 - 0.21 11.6 0.6 30 4.6 0.0 3.4 4 0 0 4 4 3 0 TrkA-N domain adh_short PF00106.20 KKK22386.1 - 4e-11 43.1 0.1 6.4e-11 42.4 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KKK22386.1 - 9.5e-07 28.8 0.0 1.2e-06 28.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Pyr_redox_3 PF13738.1 KKK22387.1 - 3.1e-14 53.5 1.2 1.5e-11 44.7 0.0 3.1 2 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KKK22387.1 - 6e-06 26.2 0.0 4.5e-05 23.4 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KKK22387.1 - 0.00021 19.6 0.8 0.003 15.8 0.0 2.6 2 1 1 3 3 3 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 KKK22387.1 - 0.00041 19.3 0.2 0.021 13.7 0.1 2.6 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 KKK22387.1 - 0.098 12.6 0.1 0.27 11.2 0.1 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KKK22387.1 - 0.2 12.0 0.3 0.59 10.5 0.2 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF1365 PF07103.6 KKK22388.1 - 2.5e-08 33.3 0.3 9.4e-08 31.4 0.1 1.9 2 1 0 2 2 2 1 Protein of unknown function (DUF1365) Asp PF00026.18 KKK22389.1 - 1.9e-49 168.6 0.0 2.4e-49 168.2 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KKK22389.1 - 5.3e-05 23.2 0.2 0.00031 20.7 0.1 2.1 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 KKK22389.1 - 0.0019 18.6 0.1 0.057 13.9 0.0 3.0 2 1 0 2 2 2 1 Aspartyl protease DUF3443 PF11925.3 KKK22389.1 - 0.051 12.2 0.8 0.14 10.8 0.2 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3443) MARVEL PF01284.18 KKK22390.1 - 2.2e-12 46.9 21.3 3.2e-12 46.4 14.7 1.2 1 0 0 1 1 1 1 Membrane-associating domain H_PPase PF03030.11 KKK22390.1 - 0.011 14.0 1.0 0.014 13.6 0.7 1.0 1 0 0 1 1 1 0 Inorganic H+ pyrophosphatase DUF817 PF05675.7 KKK22390.1 - 0.16 11.3 9.4 0.15 11.4 5.9 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF817) 7TMR-DISM_7TM PF07695.6 KKK22390.1 - 0.2 11.3 19.9 0.51 9.9 3.5 2.0 1 1 1 2 2 2 0 7TM diverse intracellular signalling Pkinase PF00069.20 KKK22391.1 - 1.4e-10 40.7 0.0 2.7e-10 39.8 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK22391.1 - 0.00012 21.2 0.0 0.00015 20.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Lipase_3 PF01764.20 KKK22392.1 - 9.8e-37 125.6 0.0 1.4e-36 125.1 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Lipase3_N PF03893.11 KKK22392.1 - 4.1e-08 32.9 0.3 9.8e-08 31.7 0.2 1.6 1 0 0 1 1 1 1 Lipase 3 N-terminal region DUF2974 PF11187.3 KKK22392.1 - 0.016 14.5 0.2 5.2 6.3 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) Lipase_GDSL_2 PF13472.1 KKK22393.1 - 2.3e-07 31.0 0.1 5.3e-07 29.9 0.1 1.6 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 KKK22393.1 - 0.00016 21.6 0.4 0.00044 20.1 0.3 1.7 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.1 KKK22393.1 - 0.0017 18.1 0.0 0.003 17.3 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family GST_C PF00043.20 KKK22394.1 - 6.8e-09 35.6 0.0 1.5e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KKK22394.1 - 5.3e-08 33.2 0.0 1e-07 32.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KKK22394.1 - 5.7e-08 32.5 0.1 9.7e-08 31.7 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glyco_tranf_2_3 PF13641.1 KKK22395.1 - 5.7e-12 45.9 0.0 9.3e-12 45.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 KKK22395.1 - 0.00018 20.8 0.0 0.00043 19.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 KKK22395.1 - 0.00037 20.2 0.0 0.00061 19.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 RrnaAD PF00398.15 KKK22396.1 - 2.7e-62 210.2 0.0 3.4e-62 209.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 KKK22396.1 - 3.1e-10 40.1 0.0 3.3e-09 36.8 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KKK22396.1 - 0.00011 22.6 0.0 0.00022 21.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KKK22396.1 - 0.0012 18.6 0.0 0.0018 17.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KKK22396.1 - 0.002 17.5 0.0 0.013 14.8 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase small domain CMAS PF02353.15 KKK22396.1 - 0.0031 16.6 0.0 0.0048 16.0 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PCMT PF01135.14 KKK22396.1 - 0.0039 16.7 0.0 0.017 14.6 0.0 1.8 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.1 KKK22396.1 - 0.057 13.7 0.0 0.1 12.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 KKK22396.1 - 0.11 12.9 0.0 0.19 12.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 KKK22396.1 - 0.15 11.6 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain 2OG-FeII_Oxy_2 PF13532.1 KKK22397.1 - 6e-15 55.5 0.0 9e-15 55.0 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 KKK22397.1 - 4.4e-10 39.7 0.0 7.4e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 KKK22397.1 - 0.035 14.6 0.2 0.18 12.3 0.0 2.3 1 1 1 2 2 2 0 2OG-Fe(II) oxygenase superfamily CXCL17 PF15211.1 KKK22397.1 - 0.054 13.8 3.3 0.087 13.2 2.3 1.3 1 0 0 1 1 1 0 VEGF co-regulated chemokine 1 Abhydrolase_3 PF07859.8 KKK22398.1 - 4.5e-55 186.4 0.3 5.7e-55 186.1 0.2 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 KKK22398.1 - 5.1e-14 51.7 0.0 6.8e-14 51.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 KKK22398.1 - 2.6e-07 30.4 0.3 3.5e-07 30.0 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 KKK22398.1 - 0.00016 21.9 0.1 0.00022 21.5 0.1 1.3 1 0 0 1 1 1 1 Thioesterase domain Peptidase_S9 PF00326.16 KKK22398.1 - 0.001 18.3 0.0 0.0031 16.7 0.0 1.8 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 KKK22398.1 - 0.0014 18.0 0.0 0.0023 17.4 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase MOZART2 PF12926.2 KKK22398.1 - 0.079 12.5 0.1 0.21 11.2 0.0 1.7 2 0 0 2 2 2 0 Mitotic-spindle organizing gamma-tubulin ring associated Esterase PF00756.15 KKK22398.1 - 0.088 12.2 0.0 0.15 11.4 0.0 1.4 1 1 0 1 1 1 0 Putative esterase COesterase PF00135.23 KKK22398.1 - 0.089 11.4 1.0 0.11 11.1 0.1 1.6 2 0 0 2 2 2 0 Carboxylesterase family BAAT_C PF08840.6 KKK22398.1 - 0.098 12.3 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal MT-A70 PF05063.9 KKK22402.1 - 1.8e-23 83.0 0.2 4e-23 81.8 0.2 1.6 1 0 0 1 1 1 1 MT-A70 Peptidase_C12 PF01088.16 KKK22403.1 - 2.4e-55 187.0 0.0 2.9e-55 186.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 DcpS PF05652.7 KKK22404.1 - 1.1e-31 109.5 0.0 1.6e-31 108.9 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal DcpS_C PF11969.3 KKK22404.1 - 6e-30 103.8 0.0 9.4e-30 103.2 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding Nop53 PF07767.6 KKK22405.1 - 2.6e-122 408.5 31.0 2.6e-122 408.5 21.5 3.1 3 0 0 3 3 3 1 Nop53 (60S ribosomal biogenesis) RNase_H2_suC PF08615.6 KKK22405.1 - 4.4e-29 101.0 2.3 1.4e-28 99.4 0.0 2.9 3 0 0 3 3 3 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) RNase_T PF00929.19 KKK22405.1 - 4.2e-26 92.1 0.0 3.8e-25 89.0 0.0 2.4 2 0 0 2 2 2 1 Exonuclease Myb_Cef PF11831.3 KKK22406.1 - 4.6e-66 222.3 1.1 4.6e-66 222.3 0.8 3.8 4 0 0 4 4 4 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.26 KKK22406.1 - 1.2e-20 73.2 4.1 2.6e-09 36.9 0.2 3.3 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KKK22406.1 - 1.2e-19 70.1 4.4 4.3e-13 49.1 0.6 3.1 2 1 1 3 3 3 2 Myb-like DNA-binding domain MOZ_SAS PF01853.13 KKK22407.1 - 6.1e-85 283.2 0.1 9.2e-85 282.6 0.0 1.3 1 0 0 1 1 1 1 MOZ/SAS family Tudor-knot PF11717.3 KKK22407.1 - 1.7e-22 78.8 0.0 3.8e-22 77.7 0.0 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Myb_Cef PF11831.3 KKK22407.1 - 0.00016 21.0 3.5 0.0053 16.0 2.4 2.2 1 1 0 1 1 1 1 pre-mRNA splicing factor component DUF2314 PF10077.4 KKK22407.1 - 0.069 13.2 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2314) Acetyltransf_1 PF00583.19 KKK22407.1 - 0.15 12.1 0.0 0.32 11.0 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family F1F0-ATPsyn_F PF10791.4 KKK22409.1 - 2.1e-36 124.0 0.3 2.4e-36 123.8 0.2 1.0 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi ETC_C1_NDUFA4 PF04800.7 KKK22410.1 - 1.8e-37 127.2 0.7 2.5e-37 126.7 0.5 1.2 1 0 0 1 1 1 1 ETC complex I subunit conserved region Glyco_hydro_72 PF03198.9 KKK22412.1 - 4.7e-130 433.1 4.0 6.3e-130 432.7 2.8 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.8 KKK22412.1 - 1.5e-23 83.0 5.2 4.6e-23 81.4 3.6 1.9 1 0 0 1 1 1 1 X8 domain Glyco_hydro_2_C PF02836.12 KKK22412.1 - 6.5e-05 21.9 0.0 0.0001 21.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Fungal_trans PF04082.13 KKK22413.1 - 6.4e-16 57.9 0.6 1.1e-15 57.2 0.5 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK22413.1 - 3.5e-05 23.6 15.3 7.7e-05 22.5 10.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 KKK22414.1 - 0.3 9.7 16.7 1.3 7.7 4.2 2.4 1 1 1 2 2 2 0 Major Facilitator Superfamily PUF PF00806.14 KKK22415.1 - 1.3e-27 93.6 0.0 1.4e-05 24.2 0.0 6.1 6 0 0 6 6 6 5 Pumilio-family RNA binding repeat RRM_1 PF00076.17 KKK22415.1 - 5.6e-11 41.9 0.0 1.1e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KKK22415.1 - 5.6e-08 32.5 0.0 1.2e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KKK22415.1 - 4.4e-05 23.3 0.0 0.0001 22.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) YL1 PF05764.8 KKK22416.1 - 9.2e-63 212.0 23.4 9.2e-63 212.0 16.2 3.9 3 1 0 3 3 3 1 YL1 nuclear protein YL1_C PF08265.6 KKK22416.1 - 2e-12 46.4 0.5 1.3e-11 43.8 0.1 2.2 2 0 0 2 2 2 1 YL1 nuclear protein C-terminal domain TFIIS_C PF01096.13 KKK22417.1 - 3.8e-15 55.2 9.5 1.4e-14 53.4 1.8 3.1 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 KKK22417.1 - 0.0015 18.1 0.2 0.0015 18.1 0.1 2.6 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit DZR PF12773.2 KKK22417.1 - 0.0074 16.0 5.6 0.48 10.2 3.9 2.4 1 1 0 1 1 1 1 Double zinc ribbon Lar_restr_allev PF14354.1 KKK22417.1 - 0.016 15.5 5.7 2.1 8.7 0.3 3.2 2 1 0 2 2 2 0 Restriction alleviation protein Lar Zn-ribbon_8 PF09723.5 KKK22417.1 - 0.13 12.2 4.4 5.8 6.9 0.1 3.2 2 1 1 3 3 3 0 Zinc ribbon domain zinc_ribbon_2 PF13240.1 KKK22417.1 - 0.14 11.6 7.5 4 7.0 0.6 3.5 3 1 1 4 4 4 0 zinc-ribbon domain zf-ISL3 PF14690.1 KKK22417.1 - 0.17 11.9 1.0 23 5.1 0.0 3.2 3 0 0 3 3 3 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 TF_Zn_Ribbon PF08271.7 KKK22417.1 - 0.23 10.8 9.0 0.97 8.8 0.1 3.5 4 0 0 4 4 4 0 TFIIB zinc-binding NMD3 PF04981.8 KKK22417.1 - 0.37 9.8 3.7 2.1 7.3 2.6 2.2 1 1 0 1 1 1 0 NMD3 family zf-C3HC4_3 PF13920.1 KKK22417.1 - 0.44 10.2 6.3 13 5.5 0.1 3.4 3 1 1 4 4 4 0 Zinc finger, C3HC4 type (RING finger) OrfB_Zn_ribbon PF07282.6 KKK22417.1 - 0.47 10.1 6.5 0.39 10.3 0.2 2.4 2 1 0 2 2 2 0 Putative transposase DNA-binding domain PhnA_Zn_Ribbon PF08274.7 KKK22417.1 - 0.66 9.8 3.2 17 5.2 0.0 2.9 3 0 0 3 3 3 0 PhnA Zinc-Ribbon zf-B_box PF00643.19 KKK22417.1 - 1.5 8.7 5.5 25 4.8 0.1 3.1 3 0 0 3 3 3 0 B-box zinc finger Zn_Tnp_IS1595 PF12760.2 KKK22417.1 - 1.8 8.4 4.9 1.7 8.5 0.1 2.8 2 1 0 2 2 2 0 Transposase zinc-ribbon domain zf-ribbon_3 PF13248.1 KKK22417.1 - 1.9 7.8 12.9 2.7 7.3 0.1 3.4 3 1 1 4 4 4 0 zinc-ribbon domain Nudix_N_2 PF14803.1 KKK22417.1 - 3 7.6 8.5 2.3 7.9 2.2 2.9 2 1 0 2 2 2 0 Nudix N-terminal HEAT_2 PF13646.1 KKK22418.1 - 3e-31 107.5 2.1 2e-14 53.6 0.0 3.4 3 1 1 4 4 4 2 HEAT repeats HEAT_PBS PF03130.11 KKK22418.1 - 6.4e-20 69.5 0.1 0.023 15.1 0.0 6.8 7 0 0 7 7 7 5 PBS lyase HEAT-like repeat HEAT_EZ PF13513.1 KKK22418.1 - 1.3e-10 41.3 4.1 0.0092 16.4 0.1 5.3 5 2 1 6 6 6 3 HEAT-like repeat HEAT PF02985.17 KKK22418.1 - 6.1e-08 32.1 2.0 4.7 7.5 0.0 6.5 7 0 0 7 7 7 2 HEAT repeat Cohesin_HEAT PF12765.2 KKK22418.1 - 0.017 15.0 0.3 0.69 9.9 0.0 3.3 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion RuvA_C PF07499.8 KKK22418.1 - 0.019 15.0 0.4 3.3 7.9 0.0 3.0 2 0 0 2 2 2 0 RuvA, C-terminal domain NUC153 PF08159.7 KKK22419.1 - 9.2e-13 47.5 4.7 2.1e-12 46.4 0.2 3.3 3 0 0 3 3 3 1 NUC153 domain RRM_6 PF14259.1 KKK22419.1 - 0.0045 16.9 0.0 1.7 8.7 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) PRK PF00485.13 KKK22420.1 - 2.1e-51 174.2 0.1 9e-51 172.1 0.0 1.9 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family UPRTase PF14681.1 KKK22420.1 - 2.2e-41 141.3 0.0 6.5e-41 139.8 0.0 1.7 2 0 0 2 2 2 1 Uracil phosphoribosyltransferase AAA_17 PF13207.1 KKK22420.1 - 4.9e-08 33.8 0.0 1.6e-07 32.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KKK22420.1 - 2.3e-06 27.9 0.0 8.5e-06 26.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain CPT PF07931.7 KKK22420.1 - 3e-05 23.7 0.0 6.5e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein Pribosyltran PF00156.22 KKK22420.1 - 0.017 14.8 0.0 0.14 11.8 0.0 2.2 2 0 0 2 2 2 0 Phosphoribosyl transferase domain Zeta_toxin PF06414.7 KKK22420.1 - 0.018 14.1 0.0 0.034 13.2 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin MobB PF03205.9 KKK22420.1 - 0.018 14.7 0.1 0.58 9.8 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 KKK22420.1 - 0.034 14.0 0.0 0.067 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 KKK22420.1 - 0.073 11.9 0.0 0.13 11.0 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain DUF87 PF01935.12 KKK22420.1 - 0.089 12.6 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF87 TIP49 PF06068.8 KKK22420.1 - 0.099 11.3 0.1 0.17 10.5 0.1 1.3 1 0 0 1 1 1 0 TIP49 C-terminus AAA_16 PF13191.1 KKK22420.1 - 0.12 12.3 0.0 0.29 11.0 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.1 KKK22420.1 - 0.12 12.5 0.0 0.92 9.6 0.0 2.4 3 0 0 3 3 2 0 AAA domain APS_kinase PF01583.15 KKK22420.1 - 0.14 11.7 0.1 0.97 9.0 0.0 2.1 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_5 PF07728.9 KKK22420.1 - 0.15 11.8 0.0 0.74 9.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.22 KKK22420.1 - 0.2 11.9 0.8 1.5 9.1 0.2 2.2 2 0 0 2 2 2 0 ABC transporter CLTH PF10607.4 KKK22421.1 - 2.3e-30 105.1 0.1 2.9e-30 104.8 0.1 1.1 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 KKK22421.1 - 4.4e-08 32.6 0.0 7.7e-08 31.8 0.0 1.4 1 0 0 1 1 1 1 LisH Nipped-B_C PF12830.2 KKK22422.1 - 8.9e-50 168.9 0.4 8.9e-50 168.9 0.3 3.4 3 1 1 4 4 4 1 Sister chromatid cohesion C-terminus Pyr_redox_2 PF07992.9 KKK22422.1 - 2.4e-15 56.9 0.0 4.3e-15 56.1 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Cohesin_HEAT PF12765.2 KKK22422.1 - 1.4e-12 47.2 3.0 9.1e-12 44.6 1.0 2.9 2 0 0 2 2 2 1 HEAT repeat associated with sister chromatid cohesion Pyr_redox PF00070.22 KKK22422.1 - 1e-10 41.8 0.0 9.7e-10 38.7 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase EF-hand_1 PF00036.27 KKK22422.1 - 1.7e-06 26.9 0.1 6.2e-06 25.1 0.1 2.1 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.1 KKK22422.1 - 1.1e-05 24.5 0.3 3.5e-05 22.9 0.2 1.9 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 KKK22422.1 - 1.2e-05 25.2 0.6 0.00018 21.5 0.0 3.1 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.1 KKK22422.1 - 1.8e-05 24.2 0.3 9e-05 22.0 0.2 2.3 1 0 0 1 1 1 1 EF-hand domain Adaptin_N PF01602.15 KKK22422.1 - 4.1e-05 22.1 1.6 0.00063 18.1 0.7 2.8 2 1 0 2 2 2 1 Adaptin N terminal region Xpo1 PF08389.7 KKK22422.1 - 0.014 15.3 0.1 2.4 8.0 0.0 3.8 4 0 0 4 4 4 0 Exportin 1-like protein HEAT PF02985.17 KKK22422.1 - 0.077 13.1 8.1 0.95 9.7 0.1 5.2 6 0 0 6 6 4 0 HEAT repeat Fungal_trans PF04082.13 KKK22423.1 - 1.9e-21 76.1 0.2 4.2e-21 74.9 0.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK22423.1 - 5.5e-09 35.7 12.1 9.6e-09 35.0 8.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PspB PF06667.7 KKK22423.1 - 0.047 13.6 1.5 1.4 8.9 0.0 2.4 2 0 0 2 2 2 0 Phage shock protein B DUF3608 PF12257.3 KKK22424.1 - 4.7e-72 242.2 0.0 7.1e-72 241.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3608) DEP PF00610.16 KKK22424.1 - 1.1e-30 105.1 0.8 2e-30 104.3 0.6 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Glyco_hydro_31 PF01055.21 KKK22425.1 - 1.4e-117 393.2 0.7 1.8e-117 392.9 0.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 KKK22425.1 - 3.6e-21 74.8 0.1 1.4e-19 69.6 0.2 2.8 2 0 0 2 2 2 1 Galactose mutarotase-like FNIP_N PF14636.1 KKK22426.1 - 4.1e-21 75.8 0.0 4.1e-21 75.8 0.0 3.6 2 1 0 2 2 2 1 Folliculin-interacting protein N-terminus FNIP_M PF14637.1 KKK22426.1 - 0.12 11.9 0.0 0.3 10.6 0.0 1.6 1 1 0 1 1 1 0 Folliculin-interacting protein middle domain eIF-1a PF01176.14 KKK22428.1 - 1.2e-28 98.3 0.1 1.6e-28 97.8 0.1 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 ERCC4 PF02732.10 KKK22429.1 - 6.1e-25 87.6 0.0 1.8e-24 86.0 0.0 1.9 2 0 0 2 2 2 1 ERCC4 domain HHH_5 PF14520.1 KKK22429.1 - 0.0004 20.5 0.0 0.00098 19.2 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain Cytochrome_CBB3 PF13442.1 KKK22430.1 - 0.12 12.5 0.1 0.15 12.2 0.1 1.1 1 0 0 1 1 1 0 Cytochrome C oxidase, cbb3-type, subunit III PTCB-BRCT PF12738.2 KKK22431.1 - 3.4e-11 42.8 0.0 6.3e-11 41.9 0.0 1.5 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 KKK22431.1 - 8.8e-08 32.1 0.0 1.6e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain fn3 PF00041.16 KKK22431.1 - 0.0013 18.8 0.6 0.0036 17.3 0.0 2.0 2 0 0 2 2 2 1 Fibronectin type III domain DUF605 PF04652.11 KKK22431.1 - 0.0015 18.0 14.1 0.0019 17.6 9.7 1.1 1 0 0 1 1 1 1 Vta1 like DUF3006 PF11213.3 KKK22431.1 - 0.003 17.2 0.0 0.0076 15.9 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3006) WH1 PF00568.18 KKK22432.1 - 1.8e-29 101.7 0.0 2.6e-29 101.1 0.0 1.2 1 0 0 1 1 1 1 WH1 domain MSA-2c PF12238.3 KKK22432.1 - 4 7.0 6.6 0.63 9.6 1.7 1.7 2 0 0 2 2 2 0 Merozoite surface antigen 2c Dioxygenase_C PF00775.16 KKK22439.1 - 2.2e-09 36.8 0.0 4.8e-09 35.7 0.0 1.6 1 0 0 1 1 1 1 Dioxygenase DNA_pol_A_exo1 PF01612.15 KKK22439.1 - 0.015 14.8 0.0 0.032 13.7 0.0 1.6 1 1 0 1 1 1 0 3'-5' exonuclease Pro-kuma_activ PF09286.6 KKK22440.1 - 2.6e-36 124.7 0.0 6.9e-36 123.4 0.0 1.7 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 KKK22440.1 - 6.2e-11 41.9 0.0 1.1e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 Subtilase family AA_permease_2 PF13520.1 KKK22441.1 - 6.2e-54 183.1 50.5 7.8e-54 182.8 35.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KKK22441.1 - 3.6e-22 78.3 39.1 4.8e-22 77.9 27.1 1.1 1 0 0 1 1 1 1 Amino acid permease DUF3493 PF11998.3 KKK22441.1 - 0.022 14.6 1.6 0.15 11.9 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3493) Erg28 PF03694.8 KKK22441.1 - 0.026 14.5 0.6 0.4 10.7 0.2 2.7 2 0 0 2 2 2 0 Erg28 like protein PIG-P PF08510.7 KKK22442.1 - 1.8e-42 143.9 0.1 1.8e-42 143.9 0.1 2.5 3 0 0 3 3 3 1 PIG-P Striatin PF08232.7 KKK22442.1 - 2.7e-41 141.0 8.8 2.7e-41 141.0 6.1 2.4 2 0 0 2 2 2 1 Striatin family WD40 PF00400.27 KKK22442.1 - 9.6e-29 98.2 14.6 6.2e-06 25.8 0.0 6.7 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 KKK22442.1 - 0.007 16.1 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 KKK22442.1 - 0.13 10.5 0.0 0.26 9.5 0.0 1.4 1 0 0 1 1 1 0 Cytochrome D1 heme domain Exonuc_VII_L PF02601.10 KKK22442.1 - 3.2 6.8 8.9 5.8 6.0 6.2 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Blt1 PF12754.2 KKK22443.1 - 2.7e-47 161.8 0.0 3.3e-47 161.6 0.0 1.1 1 0 0 1 1 1 1 Cell-cycle control medial ring component Gcd10p PF04189.8 KKK22444.1 - 2.1e-105 352.1 0.0 2.6e-105 351.8 0.0 1.1 1 0 0 1 1 1 1 Gcd10p family P21-Arc PF04062.9 KKK22445.1 - 5.5e-66 221.6 0.0 3.2e-65 219.1 0.0 1.8 1 1 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit His_Phos_2 PF00328.17 KKK22446.1 - 4e-12 46.1 0.2 7.4e-11 41.9 0.1 2.2 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Pro_isomerase PF00160.16 KKK22447.1 - 3.6e-38 131.2 0.0 6.9e-38 130.2 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF605 PF04652.11 KKK22447.1 - 8.4 5.6 19.9 13 5.0 13.8 1.3 1 0 0 1 1 1 0 Vta1 like HSF_DNA-bind PF00447.12 KKK22448.1 - 2.6e-29 101.4 0.2 5e-29 100.5 0.1 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding TMF_DNA_bd PF12329.3 KKK22448.1 - 0.005 16.6 2.4 0.074 12.8 0.1 2.4 2 0 0 2 2 2 1 TATA element modulatory factor 1 DNA binding Ets PF00178.17 KKK22448.1 - 0.15 12.1 0.0 0.33 11.1 0.0 1.5 1 0 0 1 1 1 0 Ets-domain Rab5-bind PF09311.6 KKK22448.1 - 0.23 11.3 4.5 1.2 8.9 1.5 2.3 2 0 0 2 2 2 0 Rabaptin-like protein Aldo_ket_red PF00248.16 KKK22449.1 - 2.9e-25 88.6 0.0 5.4e-25 87.7 0.0 1.4 1 1 0 1 1 1 1 Aldo/keto reductase family ParD PF09386.5 KKK22449.1 - 0.15 12.2 0.0 0.7 10.0 0.0 2.0 1 1 0 1 1 1 0 Antitoxin ParD DUF544 PF04424.8 KKK22450.1 - 2.2e-09 37.1 0.0 4.1e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF544) DUF221 PF02714.10 KKK22451.1 - 4e-106 354.5 26.7 4.1e-106 354.5 13.2 2.5 3 0 0 3 3 3 2 Domain of unknown function DUF221 RSN1_TM PF13967.1 KKK22451.1 - 7.1e-41 139.3 3.4 7.1e-41 139.3 2.4 2.7 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 KKK22451.1 - 7.2e-27 93.1 0.7 1.7e-26 91.9 0.5 1.7 1 0 0 1 1 1 1 Phosphate metabolism protein DUF4463 PF14703.1 KKK22451.1 - 6.7e-19 68.2 0.1 1.2e-18 67.3 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) AAA PF00004.24 KKK22452.1 - 1.6e-16 60.6 0.0 2.8e-16 59.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.6 KKK22452.1 - 2.9e-16 59.2 0.0 6.5e-16 58.0 0.0 1.6 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 KKK22452.1 - 9.4e-13 48.1 0.1 2.5e-12 46.7 0.0 1.8 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.10 KKK22452.1 - 8.4e-12 44.5 0.0 6.3e-10 38.3 0.0 2.5 3 0 0 3 3 3 1 Rad17 cell cycle checkpoint protein RuvB_N PF05496.7 KKK22452.1 - 3.1e-07 29.6 0.1 1.1e-05 24.6 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 KKK22452.1 - 3.2e-07 30.5 0.2 5.5e-06 26.5 0.1 2.7 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KKK22452.1 - 1.4e-06 27.9 0.1 3.9e-06 26.5 0.0 1.7 2 0 0 2 2 1 1 Part of AAA domain AAA_16 PF13191.1 KKK22452.1 - 2.1e-06 27.8 0.1 2.9e-05 24.1 0.1 2.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_11 PF13086.1 KKK22452.1 - 2.3e-06 27.3 0.2 0.00013 21.6 0.0 2.3 1 1 1 2 2 2 1 AAA domain DNA_pol3_delta PF06144.8 KKK22452.1 - 2e-05 24.1 0.0 3.7e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_5 PF07728.9 KKK22452.1 - 2.4e-05 24.0 0.1 0.00011 21.9 0.1 2.2 1 1 1 2 2 2 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 KKK22452.1 - 4.1e-05 23.4 0.0 0.00012 22.0 0.0 1.7 1 1 1 2 2 2 1 AAA domain DUF815 PF05673.8 KKK22452.1 - 4.1e-05 22.6 0.0 6.8e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_30 PF13604.1 KKK22452.1 - 5.3e-05 22.8 0.0 9e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 KKK22452.1 - 9.1e-05 21.3 0.0 0.23 10.1 0.0 2.2 2 0 0 2 2 2 2 TIP49 C-terminus AAA_3 PF07726.6 KKK22452.1 - 0.00015 21.4 0.3 0.00046 19.7 0.1 2.0 2 1 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) PhoH PF02562.11 KKK22452.1 - 0.0006 19.1 0.0 0.43 9.7 0.0 2.3 2 0 0 2 2 2 2 PhoH-like protein AAA_24 PF13479.1 KKK22452.1 - 0.00062 19.4 0.0 0.0012 18.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.4 KKK22452.1 - 0.00097 18.1 0.0 0.0015 17.6 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) DEAD PF00270.24 KKK22452.1 - 0.0024 17.3 0.1 0.04 13.3 0.0 2.2 1 1 1 2 2 2 1 DEAD/DEAH box helicase IstB_IS21 PF01695.12 KKK22452.1 - 0.004 16.5 0.0 0.21 10.9 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_28 PF13521.1 KKK22452.1 - 0.0053 16.7 0.0 0.0094 15.9 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KKK22452.1 - 0.0065 16.7 0.0 0.015 15.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 KKK22452.1 - 0.0076 15.4 0.1 0.088 11.9 0.1 2.5 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI ResIII PF04851.10 KKK22452.1 - 0.0079 16.0 0.0 0.25 11.1 0.0 2.2 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit Arch_ATPase PF01637.13 KKK22452.1 - 0.01 15.5 0.0 0.015 15.0 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase AAA_25 PF13481.1 KKK22452.1 - 0.011 15.2 0.0 0.025 13.9 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.1 KKK22452.1 - 0.028 15.2 0.0 0.079 13.7 0.0 1.6 1 1 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 KKK22452.1 - 0.035 13.5 0.0 0.089 12.2 0.0 1.7 2 0 0 2 2 1 0 FtsK/SpoIIIE family AAA_10 PF12846.2 KKK22452.1 - 0.047 13.1 0.3 3.4 7.0 0.0 2.3 1 1 0 2 2 2 0 AAA-like domain RNA_helicase PF00910.17 KKK22452.1 - 0.06 13.5 0.0 0.14 12.3 0.0 1.7 1 0 0 1 1 1 0 RNA helicase SNF2_N PF00176.18 KKK22452.1 - 0.062 12.0 0.0 4.6 5.9 0.0 2.1 1 1 0 2 2 2 0 SNF2 family N-terminal domain NACHT PF05729.7 KKK22452.1 - 0.066 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 NACHT domain SRP54 PF00448.17 KKK22452.1 - 0.11 11.9 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Viral_helicase1 PF01443.13 KKK22452.1 - 0.12 11.9 0.0 0.3 10.5 0.0 1.7 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase DUF3431 PF11913.3 KKK22453.1 - 1.3e-89 299.5 0.5 2e-89 298.8 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) SR-25 PF10500.4 KKK22453.1 - 0.034 13.6 5.0 0.047 13.1 3.5 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Homez PF11569.3 KKK22453.1 - 0.065 12.3 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez UPF0561 PF10573.4 KKK22453.1 - 0.22 11.3 1.3 0.4 10.5 0.9 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0561 zf-C2H2_4 PF13894.1 KKK22465.1 - 0.0019 18.4 19.8 0.11 12.8 0.0 4.9 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KKK22465.1 - 0.006 16.4 0.6 0.12 12.3 0.4 2.5 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2 PF00096.21 KKK22465.1 - 0.047 14.0 24.3 0.9 10.0 0.1 5.4 5 0 0 5 5 5 0 Zinc finger, C2H2 type zf-met PF12874.2 KKK22465.1 - 0.23 11.7 1.8 10 6.4 0.4 3.1 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KKK22465.1 - 6 7.1 6.3 31 4.8 0.5 3.6 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding MUG113 PF13455.1 KKK22470.1 - 9.7e-34 115.6 0.1 2e-33 114.6 0.1 1.6 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 T5orf172 PF10544.4 KKK22470.1 - 4.3e-24 84.8 0.0 1.1e-23 83.4 0.0 1.8 1 0 0 1 1 1 1 T5orf172 domain PAT1 PF09770.4 KKK22470.1 - 3 5.9 15.6 4 5.5 10.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 IBN_N PF03810.14 KKK22471.1 - 0.00013 21.8 0.1 0.00058 19.7 0.1 2.3 1 0 0 1 1 1 1 Importin-beta N-terminal domain Xpo1 PF08389.7 KKK22471.1 - 0.017 15.0 0.7 0.34 10.8 0.1 3.3 3 0 0 3 3 3 0 Exportin 1-like protein Peptidase_M24 PF00557.19 KKK22472.1 - 2.2e-42 144.9 0.0 3.2e-42 144.4 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 KKK22472.1 - 3.8e-22 79.1 0.0 4.9e-19 69.1 0.0 2.5 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain Sec8_exocyst PF04048.9 KKK22473.1 - 1.4e-52 177.0 3.1 4.7e-52 175.4 2.2 2.0 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain DUF2450 PF10475.4 KKK22473.1 - 8.6e-10 37.9 1.0 1.7e-09 37.0 0.7 1.4 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) Zw10 PF06248.8 KKK22473.1 - 3.3e-05 22.2 0.8 6.7e-05 21.2 0.6 1.4 1 0 0 1 1 1 1 Centromere/kinetochore Zw10 Sec5 PF15469.1 KKK22473.1 - 5.9e-05 22.8 1.1 0.00012 21.9 0.8 1.5 1 0 0 1 1 1 1 Exocyst complex component Sec5 Dor1 PF04124.7 KKK22473.1 - 0.0091 14.4 5.9 0.016 13.7 3.3 1.9 2 0 0 2 2 2 1 Dor1-like family DUF3829 PF12889.2 KKK22473.1 - 0.056 12.6 0.1 0.056 12.6 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3829) DUF812 PF05667.6 KKK22473.1 - 0.069 11.6 3.7 0.022 13.2 0.7 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF812) DPBB_1 PF03330.13 KKK22474.1 - 1.9e-11 43.8 3.2 2.5e-11 43.4 0.0 2.8 2 0 0 2 2 2 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Pollen_allerg_1 PF01357.16 KKK22474.1 - 0.0006 19.5 0.4 0.0017 18.1 0.3 1.7 1 0 0 1 1 1 1 Pollen allergen KIAA1328 PF15369.1 KKK22474.1 - 4.2 7.0 4.9 5.5 6.7 3.4 1.1 1 0 0 1 1 1 0 Uncharacterised protein KIAA1328 HLH PF00010.21 KKK22475.1 - 2.5e-13 49.5 1.9 5.9e-13 48.2 1.3 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain SAC3_GANP PF03399.11 KKK22476.1 - 3.5e-54 183.4 0.0 4.9e-54 183.0 0.0 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family CN_hydrolase PF00795.17 KKK22476.1 - 3e-10 39.7 0.0 8.4e-10 38.3 0.0 1.8 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase PCI_Csn8 PF10075.4 KKK22476.1 - 0.2 11.4 0.0 0.56 9.9 0.0 1.7 1 0 0 1 1 1 0 COP9 signalosome, subunit CSN8 DUF2841 PF11001.3 KKK22477.1 - 5.2e-52 174.9 0.4 7.8e-52 174.4 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) BLYB PF05289.6 KKK22477.1 - 0.015 15.0 0.0 0.032 14.0 0.0 1.5 1 0 0 1 1 1 0 Borrelia hemolysin accessory protein RRM_1 PF00076.17 KKK22478.1 - 1.7e-13 49.9 0.0 2.6e-13 49.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KKK22478.1 - 4e-06 26.7 0.0 7.1e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KKK22479.1 - 0.026 14.4 0.0 0.069 13.1 0.0 1.7 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Ribosomal_S16 PF00886.14 KKK22480.1 - 4e-25 87.2 0.1 5e-25 86.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S16 YjeF_N PF03853.10 KKK22481.1 - 1.6e-24 86.4 0.0 3.9e-24 85.1 0.0 1.6 1 1 1 2 2 2 1 YjeF-related protein N-terminus PUL PF08324.6 KKK22482.1 - 1.9e-56 190.8 0.0 2.5e-56 190.4 0.0 1.2 1 0 0 1 1 1 1 PUL domain PFU PF09070.6 KKK22482.1 - 1.2e-43 147.7 0.1 2.1e-43 147.0 0.0 1.4 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.27 KKK22482.1 - 3.1e-36 121.9 15.5 4e-08 32.8 0.0 7.6 7 0 0 7 7 7 6 WD domain, G-beta repeat BBS2_Mid PF14783.1 KKK22482.1 - 0.0075 16.0 0.0 0.77 9.5 0.0 3.2 2 1 1 4 4 4 1 Ciliary BBSome complex subunit 2, middle region CH PF00307.26 KKK22483.1 - 6.9e-34 116.1 0.1 5.3e-19 68.2 0.0 2.6 2 0 0 2 2 2 2 Calponin homology (CH) domain EFhand_Ca_insen PF08726.5 KKK22483.1 - 8.2e-29 99.3 0.1 2.6e-28 97.7 0.1 1.9 1 0 0 1 1 1 1 Ca2+ insensitive EF hand RRM_1 PF00076.17 KKK22483.1 - 2e-17 62.5 0.0 4.4e-17 61.4 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KKK22483.1 - 6.8e-11 41.9 0.0 1.6e-10 40.8 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) CAMSAP_CH PF11971.3 KKK22483.1 - 1.3e-08 34.3 0.2 2.3e-07 30.3 0.0 2.8 2 0 0 2 2 2 1 CAMSAP CH domain FoP_duplication PF13865.1 KKK22483.1 - 6.7e-07 29.6 5.5 6.7e-07 29.6 3.8 3.3 3 0 0 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 RRM_5 PF13893.1 KKK22483.1 - 0.00026 20.7 0.0 0.00056 19.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) EF-hand_6 PF13405.1 KKK22483.1 - 0.00086 18.9 0.0 0.0049 16.6 0.0 2.4 1 0 0 1 1 1 1 EF-hand domain EF-hand_1 PF00036.27 KKK22483.1 - 0.0044 16.2 0.1 0.035 13.3 0.0 2.5 2 0 0 2 2 2 1 EF hand DUF761 PF05553.6 KKK22483.1 - 0.0058 15.9 0.7 0.018 14.3 0.5 1.9 1 0 0 1 1 1 1 Cotton fibre expressed protein EF-hand_8 PF13833.1 KKK22483.1 - 0.01 15.4 0.1 0.043 13.4 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain pair Aldo_ket_red PF00248.16 KKK22484.1 - 9e-42 142.8 0.0 1.1e-41 142.5 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family ALMT PF11744.3 KKK22484.1 - 0.17 10.5 0.1 0.24 10.0 0.1 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter WD40 PF00400.27 KKK22485.1 - 3.8e-34 115.3 10.8 1.2e-10 40.8 0.0 6.9 7 0 0 7 7 7 6 WD domain, G-beta repeat Me-amine-dh_H PF06433.6 KKK22485.1 - 0.029 13.0 0.0 0.69 8.4 0.0 2.1 2 0 0 2 2 2 0 Methylamine dehydrogenase heavy chain (MADH) ArgJ PF01960.13 KKK22486.1 - 6.9e-144 479.0 0.1 7.8e-144 478.8 0.0 1.0 1 0 0 1 1 1 1 ArgJ family Pkinase PF00069.20 KKK22487.1 - 6.3e-20 71.4 0.0 1.2e-19 70.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK22487.1 - 2.5e-18 66.1 0.0 5e-18 65.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 KKK22487.1 - 0.039 13.3 0.0 0.083 12.2 0.0 1.5 1 0 0 1 1 1 0 RIO1 family IncA PF04156.9 KKK22487.1 - 0.37 10.3 3.3 0.64 9.5 2.3 1.3 1 0 0 1 1 1 0 IncA protein Cyclin_N PF00134.18 KKK22488.1 - 0.0035 16.8 0.0 0.073 12.6 0.0 2.6 2 1 0 2 2 2 1 Cyclin, N-terminal domain TFIIB PF00382.14 KKK22488.1 - 0.0068 16.1 0.0 0.36 10.6 0.0 2.4 2 0 0 2 2 2 1 Transcription factor TFIIB repeat Autophagy_N PF03986.8 KKK22489.1 - 5.5e-52 175.4 0.7 7.9e-52 174.9 0.0 1.6 2 0 0 2 2 2 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.10 KKK22489.1 - 1e-21 76.8 0.2 2.3e-21 75.7 0.1 1.6 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_Cterm PF10381.4 KKK22489.1 - 9.6e-15 53.3 0.3 1.5e-14 52.7 0.2 1.3 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal DUF1471 PF07338.8 KKK22489.1 - 0.036 13.6 0.4 0.091 12.4 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1471) Daxx PF03344.10 KKK22489.1 - 0.064 11.7 3.0 0.066 11.7 2.1 1.1 1 0 0 1 1 1 0 Daxx Family FAM176 PF14851.1 KKK22489.1 - 0.11 12.1 0.9 0.23 11.1 0.6 1.5 1 0 0 1 1 1 0 FAM176 family CDC27 PF09507.5 KKK22489.1 - 1.2 8.3 7.1 1.8 7.6 4.9 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Nop14 PF04147.7 KKK22489.1 - 4.5 5.0 12.0 6.4 4.5 8.3 1.2 1 0 0 1 1 1 0 Nop14-like family Nucleoplasmin PF03066.10 KKK22489.1 - 9.1 5.7 11.4 20 4.7 7.9 1.5 1 0 0 1 1 1 0 Nucleoplasmin FUN14 PF04930.10 KKK22490.1 - 1.3e-12 47.8 2.1 8.9e-12 45.1 1.4 2.0 1 1 0 1 1 1 1 FUN14 family DUF543 PF04418.7 KKK22490.1 - 0.0052 16.7 0.8 0.04 13.8 0.2 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF543) DUF4017 PF13209.1 KKK22490.1 - 0.14 11.9 0.1 0.23 11.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4017) ORC2 PF04084.9 KKK22491.1 - 1.2e-102 343.1 0.0 1.4e-102 342.8 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 2 SecY PF00344.15 KKK22493.1 - 2.6e-97 325.8 8.0 3.2e-97 325.5 5.5 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.4 KKK22493.1 - 2.6e-18 65.2 0.3 7.8e-18 63.6 0.2 1.9 1 0 0 1 1 1 1 Plug domain of Sec61p FA_desaturase PF00487.19 KKK22494.1 - 0.025 14.0 10.9 0.42 10.0 7.6 2.0 1 1 0 1 1 1 0 Fatty acid desaturase RP-C_C PF11800.3 KKK22494.1 - 0.89 9.2 5.8 0.66 9.6 3.3 1.4 1 1 0 1 1 1 0 Replication protein C C-terminal region DUF605 PF04652.11 KKK22494.1 - 2.7 7.2 15.4 3 7.1 10.7 1.0 1 0 0 1 1 1 0 Vta1 like Suf PF05843.9 KKK22494.1 - 2.9 7.5 7.2 3.4 7.3 5.0 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Pap_E4 PF02711.9 KKK22494.1 - 4.2 8.2 14.3 0.4 11.5 6.2 1.9 1 1 1 2 2 2 0 E4 protein SOR_SNZ PF01680.12 KKK22495.1 - 9.5e-110 365.0 3.2 1.5e-109 364.4 2.2 1.3 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.9 KKK22495.1 - 6.1e-09 35.3 6.1 2.7e-06 26.6 0.1 2.4 2 1 0 2 2 2 2 Thiazole biosynthesis protein ThiG His_biosynth PF00977.16 KKK22495.1 - 0.0014 17.9 0.3 0.024 13.8 0.0 2.6 3 0 0 3 3 3 1 Histidine biosynthesis protein Dus PF01207.12 KKK22495.1 - 0.002 16.9 1.0 0.92 8.2 0.0 2.3 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) IGPS PF00218.16 KKK22495.1 - 0.0033 16.5 0.2 0.069 12.1 0.0 2.3 2 1 0 2 2 2 1 Indole-3-glycerol phosphate synthase NanE PF04131.9 KKK22495.1 - 0.02 13.8 0.9 0.24 10.3 0.0 2.5 2 1 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase NMO PF03060.10 KKK22495.1 - 0.029 13.5 0.2 0.029 13.5 0.1 2.3 2 1 0 2 2 2 0 Nitronate monooxygenase TMP-TENI PF02581.12 KKK22495.1 - 0.087 11.9 1.0 1.5 7.9 0.0 3.0 3 0 0 3 3 3 0 Thiamine monophosphate synthase/TENI NUDIX PF00293.23 KKK22496.1 - 0.00014 21.5 0.0 0.00031 20.3 0.0 1.7 1 1 0 1 1 1 1 NUDIX domain NUDIX PF00293.23 KKK22497.1 - 2.6e-18 65.9 0.0 4e-18 65.3 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain HAD_2 PF13419.1 KKK22498.1 - 4.6e-16 59.5 0.0 6.8e-16 58.9 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KKK22498.1 - 3.5e-07 29.8 0.0 6e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 KKK22498.1 - 0.00022 21.6 0.1 0.0017 18.7 0.1 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase NIF PF03031.13 KKK22498.1 - 0.023 14.3 0.0 0.42 10.2 0.0 2.1 2 0 0 2 2 2 0 NLI interacting factor-like phosphatase Init_tRNA_PT PF04179.7 KKK22499.1 - 2.3e-173 577.2 0.0 2.6e-173 577.0 0.0 1.0 1 0 0 1 1 1 1 Initiator tRNA phosphoribosyl transferase Glycos_transf_2 PF00535.21 KKK22501.1 - 4.7e-21 75.2 0.0 6.2e-11 42.2 0.0 2.4 1 1 0 2 2 2 2 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 KKK22501.1 - 6.1e-06 26.1 0.1 0.024 14.4 0.1 3.2 2 2 1 3 3 3 2 Glycosyltransferase like family 2 LrgB PF04172.11 KKK22501.1 - 0.049 12.7 0.0 0.11 11.6 0.0 1.6 1 0 0 1 1 1 0 LrgB-like family EST1_DNA_bind PF10373.4 KKK22502.1 - 7.3e-12 45.0 0.7 1.6e-11 43.9 0.0 2.0 2 1 0 2 2 2 1 Est1 DNA/RNA binding domain zf-C3HC4_3 PF13920.1 KKK22503.1 - 4.2e-13 48.7 6.0 6.3e-13 48.1 4.2 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KKK22503.1 - 3.5e-08 33.3 8.2 5.5e-08 32.7 5.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KKK22503.1 - 1.4e-06 27.8 6.9 2.3e-06 27.1 4.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KKK22503.1 - 1.9e-06 27.6 7.1 3.1e-06 26.9 4.9 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 KKK22503.1 - 0.0001 21.9 6.0 0.00016 21.3 4.1 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_4 PF14570.1 KKK22503.1 - 0.063 12.8 5.6 0.11 12.0 3.9 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 KKK22503.1 - 0.084 12.7 7.3 0.16 11.9 5.1 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 KKK22503.1 - 0.12 12.0 5.2 0.084 12.6 2.0 2.0 1 1 1 2 2 2 0 RING-type zinc-finger Prok-RING_4 PF14447.1 KKK22503.1 - 1.3 8.6 5.8 3.5 7.2 1.0 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 Phosphoprotein PF00922.12 KKK22505.1 - 8.3 5.5 6.7 1.2 8.2 1.5 1.8 1 1 1 2 2 2 0 Vesiculovirus phosphoprotein Mucin PF01456.12 KKK22521.1 - 1.8 8.3 10.4 3.4 7.4 7.2 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein RabGAP-TBC PF00566.13 KKK22522.1 - 8.1e-13 48.3 5.7 1.2e-12 47.7 4.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF4116 PF13475.1 KKK22522.1 - 0.13 11.8 0.3 0.29 10.6 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) Rootletin PF15035.1 KKK22552.1 - 0.00044 20.2 7.0 0.00069 19.6 4.8 1.3 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion Med4 PF10018.4 KKK22552.1 - 0.0012 18.3 3.7 0.0012 18.3 2.6 1.8 2 0 0 2 2 2 1 Vitamin-D-receptor interacting Mediator subunit 4 Herpes_UL6 PF01763.11 KKK22552.1 - 0.0013 17.0 1.8 0.0017 16.6 1.3 1.1 1 0 0 1 1 1 1 Herpesvirus UL6 like DUF3450 PF11932.3 KKK22552.1 - 0.014 14.7 5.6 0.021 14.1 3.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Tropomyosin_1 PF12718.2 KKK22552.1 - 0.052 13.3 5.9 0.1 12.4 4.1 1.4 1 0 0 1 1 1 0 Tropomyosin like DUF972 PF06156.8 KKK22552.1 - 0.065 13.5 7.7 0.042 14.2 3.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF972) TMF_DNA_bd PF12329.3 KKK22552.1 - 0.081 12.7 5.8 0.18 11.6 4.0 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding NTR2 PF15458.1 KKK22552.1 - 0.11 11.7 11.7 0.23 10.6 8.1 1.5 1 0 0 1 1 1 0 Nineteen complex-related protein 2 DivIC PF04977.10 KKK22552.1 - 0.34 10.4 10.0 0.99 8.9 7.0 1.8 1 1 0 1 1 1 0 Septum formation initiator bZIP_1 PF00170.16 KKK22552.1 - 0.4 10.6 7.2 2.2 8.2 5.0 2.2 1 1 0 1 1 1 0 bZIP transcription factor 7tm_7 PF08395.7 KKK22552.1 - 0.44 9.5 1.9 0.72 8.8 1.3 1.2 1 0 0 1 1 1 0 7tm Chemosensory receptor DUF904 PF06005.7 KKK22552.1 - 0.58 10.4 11.8 0.4 10.9 6.9 1.7 2 0 0 2 2 1 0 Protein of unknown function (DUF904) DUF3886 PF13025.1 KKK22552.1 - 1 9.3 10.1 2.1 8.3 7.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3886) IncA PF04156.9 KKK22552.1 - 2.6 7.6 19.9 0.23 11.0 9.9 1.8 1 1 1 2 2 2 0 IncA protein GP41 PF00517.12 KKK22552.1 - 4.2 6.8 11.7 2.5 7.5 6.7 1.6 1 1 1 2 2 2 0 Retroviral envelope protein Anp1 PF03452.9 KKK22553.1 - 8.9e-109 362.8 0.0 1.1e-108 362.5 0.0 1.1 1 0 0 1 1 1 1 Anp1 Asn_synthase PF00733.16 KKK22554.1 - 2e-68 230.6 0.0 2.7e-68 230.2 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 KKK22554.1 - 4.5e-35 120.0 0.0 7.5e-35 119.3 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 KKK22554.1 - 5.2e-25 87.9 0.0 9.6e-25 87.0 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.3 KKK22554.1 - 4.8e-10 39.0 0.0 9.2e-10 38.1 0.0 1.4 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.12 KKK22554.1 - 0.00049 19.0 0.0 0.00099 18.0 0.0 1.6 1 1 0 1 1 1 1 NAD synthase GATase_2 PF00310.16 KKK22554.1 - 0.018 13.7 0.0 3.1 6.4 0.0 2.9 1 1 2 3 3 3 0 Glutamine amidotransferases class-II DUF2939 PF11159.3 KKK22554.1 - 0.06 13.5 0.0 0.35 11.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2939) Porin_3 PF01459.17 KKK22555.1 - 7.3e-68 228.8 0.0 1.3e-67 228.0 0.0 1.4 1 1 0 1 1 1 1 Eukaryotic porin KdpC PF02669.10 KKK22555.1 - 0.029 14.0 0.6 0.064 12.9 0.3 1.6 2 0 0 2 2 2 0 K+-transporting ATPase, c chain Serglycin PF04360.7 KKK22556.1 - 0.0072 16.0 0.9 0.014 15.1 0.6 1.5 1 0 0 1 1 1 1 Serglycin YCII PF03795.9 KKK22557.1 - 0.056 13.6 0.0 0.06 13.5 0.0 1.1 1 0 0 1 1 1 0 YCII-related domain AMP-binding PF00501.23 KKK22558.1 - 7.1e-83 278.3 0.0 9.1e-83 277.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KKK22558.1 - 3.3e-13 50.3 0.0 1.8e-12 48.0 0.0 2.2 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain GH3 PF03321.8 KKK22558.1 - 0.0019 16.7 0.0 0.009 14.5 0.0 1.8 2 0 0 2 2 2 1 GH3 auxin-responsive promoter G-patch PF01585.18 KKK22559.1 - 1.1e-10 41.1 1.3 2.3e-10 40.0 0.9 1.6 1 0 0 1 1 1 1 G-patch domain RRM_5 PF13893.1 KKK22559.1 - 0.00013 21.7 0.0 0.00026 20.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KKK22559.1 - 0.00017 21.1 0.2 0.00056 19.4 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) G-patch_2 PF12656.2 KKK22559.1 - 0.012 15.4 0.7 0.036 13.9 0.5 1.8 1 0 0 1 1 1 0 DExH-box splicing factor binding site UQ_con PF00179.21 KKK22560.1 - 1.2e-48 164.1 0.0 1.3e-48 163.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KKK22560.1 - 0.00012 21.7 0.0 0.00015 21.4 0.0 1.3 1 1 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 KKK22560.1 - 0.05 13.5 0.6 0.069 13.0 0.4 1.5 1 1 0 1 1 1 0 RWD domain Diphthamide_syn PF01866.12 KKK22561.1 - 1.8e-52 178.5 0.0 4.1e-52 177.3 0.0 1.5 2 0 0 2 2 2 1 Putative diphthamide synthesis protein Myc_N PF01056.13 KKK22561.1 - 2.2 7.3 5.7 3.9 6.5 4.0 1.3 1 0 0 1 1 1 0 Myc amino-terminal region Fe-ADH PF00465.14 KKK22562.1 - 3e-29 101.7 0.0 3.3e-29 101.6 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Cutinase PF01083.17 KKK22563.1 - 1.9e-52 177.5 0.0 2.2e-52 177.4 0.0 1.0 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.6 KKK22563.1 - 0.0002 20.8 0.0 0.0003 20.2 0.0 1.3 1 0 0 1 1 1 1 PE-PPE domain VirJ PF06057.6 KKK22563.1 - 0.0079 15.9 0.0 0.011 15.5 0.0 1.2 1 0 0 1 1 1 1 Bacterial virulence protein (VirJ) Methyltransf_6 PF03737.10 KKK22563.1 - 0.02 14.7 0.0 0.028 14.2 0.0 1.3 1 0 0 1 1 1 0 Demethylmenaquinone methyltransferase DUF2974 PF11187.3 KKK22563.1 - 0.035 13.4 0.0 0.046 13.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Abhydrolase_2 PF02230.11 KKK22563.1 - 0.074 12.4 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase CS PF04969.11 KKK22564.1 - 1.1e-18 67.5 0.0 2.3e-18 66.5 0.0 1.6 1 0 0 1 1 1 1 CS domain Zn_clus PF00172.13 KKK22566.1 - 3.5e-10 39.6 10.1 6.2e-10 38.8 7.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ADH_N PF08240.7 KKK22588.1 - 2e-34 117.5 1.1 2e-34 117.5 0.7 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KKK22588.1 - 5.6e-23 80.9 0.3 9.6e-23 80.1 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KKK22588.1 - 0.002 19.0 0.1 0.0033 18.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_18 PF12847.2 KKK22588.1 - 0.0028 18.1 0.0 0.005 17.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain UDPG_MGDP_dh_N PF03721.9 KKK22588.1 - 0.02 14.2 0.0 0.032 13.6 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox_3 PF13738.1 KKK22588.1 - 0.045 13.8 0.0 0.073 13.1 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase MTS PF05175.9 KKK22588.1 - 0.064 12.6 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain 2-Hacid_dh_C PF02826.14 KKK22588.1 - 0.069 12.2 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF1735 PF08522.5 KKK22588.1 - 0.14 12.5 0.0 0.27 11.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1735) PrmA PF06325.8 KKK22588.1 - 0.16 11.0 0.1 0.23 10.5 0.1 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) AlaDh_PNT_C PF01262.16 KKK22588.1 - 0.25 10.8 2.9 0.13 11.8 0.5 1.6 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Ras PF00071.17 KKK22589.1 - 3.7e-38 130.4 0.0 6.9e-38 129.5 0.0 1.4 1 1 0 1 1 1 1 Ras family Miro PF08477.8 KKK22589.1 - 2.8e-12 47.1 0.0 4.7e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KKK22589.1 - 1.6e-11 43.7 0.0 1.9e-10 40.2 0.0 2.0 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KKK22589.1 - 0.00044 19.7 0.0 0.00092 18.6 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 KKK22589.1 - 0.0011 18.1 0.0 0.0015 17.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KKK22589.1 - 0.0089 15.9 0.0 0.014 15.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_33 PF13671.1 KKK22589.1 - 0.0093 15.8 0.0 0.02 14.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain PduV-EutP PF10662.4 KKK22589.1 - 0.013 15.0 0.0 2.2 7.7 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.1 KKK22589.1 - 0.018 15.2 0.0 0.068 13.3 0.0 2.0 2 1 0 2 2 2 0 AAA domain DUF258 PF03193.11 KKK22589.1 - 0.029 13.5 0.0 0.047 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 KKK22589.1 - 0.049 13.6 0.0 0.2 11.6 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain SRPRB PF09439.5 KKK22589.1 - 0.095 11.9 0.0 0.17 11.1 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit ABC_tran PF00005.22 KKK22589.1 - 0.096 12.9 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 ABC transporter FAD-oxidase_C PF02913.14 KKK22590.1 - 2.8e-57 193.9 0.1 4.6e-57 193.1 0.1 1.4 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 KKK22590.1 - 1.3e-35 121.8 0.0 4.4e-35 120.1 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain NIF PF03031.13 KKK22594.1 - 3.2e-51 173.1 0.1 4.5e-51 172.6 0.1 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase LRR_4 PF12799.2 KKK22595.1 - 1.5e-23 81.9 32.3 2.3e-07 30.2 1.3 4.3 1 1 5 6 6 6 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KKK22595.1 - 2.2e-12 46.5 12.0 4.7e-05 23.0 4.3 3.4 2 1 0 3 3 3 3 Leucine rich repeat LRR_1 PF00560.28 KKK22595.1 - 1.3e-09 36.7 10.4 0.079 13.0 0.7 7.0 7 0 0 7 7 7 2 Leucine Rich Repeat LRR_6 PF13516.1 KKK22595.1 - 9.8e-08 31.3 8.7 0.14 12.2 0.4 6.8 4 1 3 7 7 7 2 Leucine Rich repeat LRR_7 PF13504.1 KKK22595.1 - 3.3e-06 26.4 5.5 0.27 11.6 0.2 6.3 7 0 0 7 7 7 1 Leucine rich repeat LRR_9 PF14580.1 KKK22595.1 - 4.4e-05 23.1 5.8 8.5e-05 22.1 2.2 2.0 1 1 1 2 2 2 2 Leucine-rich repeat Nop16 PF09420.5 KKK22607.1 - 4.2e-60 202.5 8.0 4.8e-60 202.3 5.6 1.0 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 Zip PF02535.17 KKK22608.1 - 2.8e-62 210.5 4.8 9.3e-62 208.8 3.3 1.8 1 1 0 1 1 1 1 ZIP Zinc transporter Anp1 PF03452.9 KKK22609.1 - 2.5e-108 361.3 0.0 3.3e-108 360.9 0.0 1.0 1 0 0 1 1 1 1 Anp1 Glycos_transf_2 PF00535.21 KKK22609.1 - 0.0061 16.2 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Mito_carr PF00153.22 KKK22610.1 - 1.8e-57 191.0 0.3 2.6e-20 71.9 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein bZIP_1 PF00170.16 KKK22611.1 - 2.1e-08 34.0 14.3 3.7e-08 33.2 9.9 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KKK22611.1 - 0.0018 18.0 16.3 0.0028 17.4 10.6 1.8 1 1 1 2 2 2 1 Basic region leucine zipper TMF_TATA_bd PF12325.3 KKK22611.1 - 0.013 15.2 3.9 0.022 14.4 2.7 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding CCDC155 PF14662.1 KKK22611.1 - 0.023 14.3 7.2 0.036 13.6 5.0 1.2 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 DUF724 PF05266.9 KKK22611.1 - 0.071 12.7 5.6 0.14 11.7 3.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF724) bZIP_Maf PF03131.12 KKK22611.1 - 0.072 13.3 9.8 0.13 12.5 6.8 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor Adeno_PIX PF03955.9 KKK22611.1 - 1.2 9.6 3.8 11 6.6 1.8 2.3 2 0 0 2 2 2 0 Adenovirus hexon-associated protein (IX) Phosducin PF02114.11 KKK22612.1 - 5.2e-06 25.3 0.0 5.6e-06 25.2 0.0 1.1 1 0 0 1 1 1 1 Phosducin Kelch_3 PF13415.1 KKK22613.1 - 3.5e-37 125.7 14.3 1.7e-08 34.3 0.1 6.0 6 0 0 6 6 6 5 Galactose oxidase, central domain Pkinase PF00069.20 KKK22613.1 - 4.1e-37 127.7 0.0 7.9e-37 126.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Kelch_4 PF13418.1 KKK22613.1 - 1e-32 111.6 10.8 3.6e-08 33.0 0.9 6.8 6 1 1 7 7 7 6 Galactose oxidase, central domain Kelch_5 PF13854.1 KKK22613.1 - 1.1e-30 105.0 3.9 7.9e-08 32.0 0.1 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_1 PF01344.20 KKK22613.1 - 2e-29 100.8 0.1 9.9e-11 41.0 0.1 6.3 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.1 KKK22613.1 - 9.7e-26 88.8 9.5 1.9e-10 40.4 0.5 6.5 3 2 3 6 6 6 5 Kelch motif Kelch_2 PF07646.10 KKK22613.1 - 3.5e-20 70.9 7.2 2.1e-08 33.6 0.3 6.5 6 0 0 6 6 6 4 Kelch motif Pkinase_Tyr PF07714.12 KKK22613.1 - 1.7e-12 46.9 0.0 2.9e-12 46.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase RAG2 PF03089.9 KKK22613.1 - 0.015 14.0 0.1 0.19 10.4 0.0 2.7 3 1 1 4 4 4 0 Recombination activating protein 2 FHA PF00498.21 KKK22617.1 - 8.7e-17 61.0 0.0 1.8e-16 60.0 0.0 1.6 1 0 0 1 1 1 1 FHA domain ERM PF00769.14 KKK22617.1 - 0.00017 21.2 9.1 0.00017 21.2 6.3 3.2 3 0 0 3 3 3 2 Ezrin/radixin/moesin family CENP-Q PF13094.1 KKK22617.1 - 0.0046 17.0 13.8 0.0046 17.0 9.5 3.3 2 1 1 3 3 3 1 CENP-Q, a CENPA-CAD centromere complex subunit Romo1 PF10247.4 KKK22618.1 - 4.5e-29 100.4 13.0 5.6e-29 100.1 9.0 1.1 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 Tim17 PF02466.14 KKK22618.1 - 3.9 7.5 9.4 7.5 6.6 0.3 2.0 1 1 1 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family RTA1 PF04479.8 KKK22619.1 - 1.4e-42 145.7 5.4 1.4e-42 145.7 3.8 1.5 2 0 0 2 2 2 1 RTA1 like protein DUF4239 PF14023.1 KKK22619.1 - 0.1 11.9 3.4 0.19 11.0 2.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) DUF3439 PF11921.3 KKK22620.1 - 0.00033 20.4 6.6 0.021 14.5 1.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF3439) SSP160 PF06933.6 KKK22620.1 - 0.032 12.2 4.0 0.039 11.9 2.7 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Mucin PF01456.12 KKK22620.1 - 0.035 13.9 8.3 0.061 13.0 5.8 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Med3 PF11593.3 KKK22620.1 - 0.29 10.3 2.1 0.37 9.9 1.5 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal zf-RING_2 PF13639.1 KKK22621.1 - 4.4e-14 52.0 5.8 7.1e-14 51.3 4.0 1.3 1 0 0 1 1 1 1 Ring finger domain PA PF02225.17 KKK22621.1 - 3.8e-11 42.5 0.0 8.5e-11 41.4 0.0 1.6 1 0 0 1 1 1 1 PA domain zf-C3HC4_2 PF13923.1 KKK22621.1 - 2e-09 37.3 5.2 3.3e-09 36.6 3.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KKK22621.1 - 3.9e-09 36.4 1.8 7.2e-09 35.6 1.2 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 KKK22621.1 - 1.2e-08 34.5 3.6 1.8e-08 33.8 2.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KKK22621.1 - 3.2e-08 33.1 3.2 4.8e-08 32.5 2.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KKK22621.1 - 1.1e-07 31.3 2.8 1.8e-07 30.7 2.0 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 KKK22621.1 - 0.00046 19.9 0.7 0.0009 19.0 0.5 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 KKK22621.1 - 0.014 15.1 2.9 0.035 13.8 2.0 1.8 1 0 0 1 1 1 0 RING-type zinc-finger FANCL_C PF11793.3 KKK22621.1 - 0.038 13.9 2.5 0.1 12.5 1.7 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.2 KKK22621.1 - 0.053 13.5 4.2 0.096 12.7 2.9 1.4 1 0 0 1 1 1 0 RING-variant domain zf-C3HC4_4 PF15227.1 KKK22621.1 - 0.065 13.1 3.4 0.19 11.6 2.4 1.8 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 KKK22621.1 - 0.36 10.4 3.0 0.62 9.6 2.1 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain PHD PF00628.24 KKK22621.1 - 0.65 9.7 3.0 1.2 8.9 2.1 1.4 1 0 0 1 1 1 0 PHD-finger zf-RING-like PF08746.6 KKK22621.1 - 2.2 8.3 3.8 4.1 7.4 2.7 1.5 1 0 0 1 1 1 0 RING-like domain Ribosomal_L44 PF00935.14 KKK22622.1 - 0.54 10.3 5.0 0.43 10.6 0.7 2.5 1 1 1 2 2 2 0 Ribosomal protein L44 Rpp20 PF12328.3 KKK22623.1 - 4.4e-54 182.0 3.6 5.7e-54 181.6 2.5 1.1 1 0 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.16 KKK22623.1 - 3.5e-23 80.9 0.9 5.9e-23 80.2 0.6 1.4 1 0 0 1 1 1 1 Alba Disulph_isomer PF06491.6 KKK22624.1 - 0.063 13.1 0.2 0.072 12.9 0.2 1.2 1 0 0 1 1 1 0 Disulphide isomerase LRR_8 PF13855.1 KKK22625.1 - 3.6e-13 49.0 1.9 1.3e-08 34.4 0.4 2.6 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.2 KKK22625.1 - 4.3e-12 45.3 4.6 3e-07 29.8 1.0 3.2 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KKK22625.1 - 4.9e-06 25.8 8.7 0.071 13.1 0.0 5.0 5 0 0 5 5 5 2 Leucine Rich Repeat LRR_7 PF13504.1 KKK22625.1 - 0.00017 21.2 4.4 0.23 11.7 0.0 4.1 3 0 0 3 3 3 2 Leucine rich repeat Raptor_N PF14538.1 KKK22626.1 - 1.3e-64 216.6 0.0 2.9e-64 215.5 0.0 1.7 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain WD40 PF00400.27 KKK22626.1 - 5.1e-07 29.3 7.2 0.33 10.8 0.0 6.0 6 0 0 6 6 6 2 WD domain, G-beta repeat Kdo PF06293.9 KKK22626.1 - 1.8e-05 23.9 0.3 3.7e-05 22.8 0.2 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Peptidase_C14 PF00656.17 KKK22626.1 - 0.0023 17.6 0.0 0.004 16.8 0.0 1.3 1 0 0 1 1 1 1 Caspase domain BBS2_Mid PF14783.1 KKK22626.1 - 0.0041 16.8 1.7 0.71 9.6 0.1 2.9 2 1 1 3 3 3 2 Ciliary BBSome complex subunit 2, middle region RIO1 PF01163.17 KKK22626.1 - 0.01 15.1 0.0 0.02 14.2 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Atx10homo_assoc PF09759.4 KKK22626.1 - 0.031 13.9 0.1 0.075 12.7 0.0 1.6 1 0 0 1 1 1 0 Spinocerebellar ataxia type 10 protein domain Pkinase PF00069.20 KKK22626.1 - 0.082 12.0 0.1 0.15 11.1 0.1 1.3 1 0 0 1 1 1 0 Protein kinase domain WaaY PF06176.6 KKK22626.1 - 0.17 11.0 0.1 1.2 8.3 0.0 2.0 2 0 0 2 2 2 0 Lipopolysaccharide core biosynthesis protein (WaaY) DnaJ PF00226.26 KKK22627.1 - 6.5e-26 89.8 1.5 1.2e-25 89.0 1.1 1.4 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 KKK22627.1 - 1.8e-23 82.1 0.3 1.7e-19 69.4 0.0 2.7 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 KKK22627.1 - 8.5e-14 51.3 17.6 1.6e-13 50.4 12.2 1.5 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 KKK22627.1 - 0.052 13.2 8.9 0.036 13.7 1.4 2.3 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family DUF2614 PF11023.3 KKK22627.1 - 0.65 9.7 5.7 3.9 7.3 0.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2614) zf-RING_3 PF14369.1 KKK22627.1 - 1.7 8.6 3.8 27 4.8 0.1 2.9 3 0 0 3 3 3 0 zinc-finger zinc-ribbons_6 PF07191.7 KKK22627.1 - 3.8 7.3 5.6 9.8 6.0 0.9 2.3 2 0 0 2 2 2 0 zinc-ribbons dCMP_cyt_deam_1 PF00383.17 KKK22628.1 - 4.5e-19 67.9 0.0 6.9e-19 67.3 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 KKK22628.1 - 0.00099 18.9 2.0 0.06 13.1 0.6 2.2 1 1 1 2 2 2 2 Bd3614-like deaminase XOO_2897-deam PF14440.1 KKK22628.1 - 0.001 18.7 0.0 0.0032 17.1 0.0 1.7 1 1 1 2 2 2 1 Xanthomonas XOO_2897-like deaminase APOBEC_N PF08210.6 KKK22628.1 - 0.032 13.8 0.1 0.041 13.5 0.0 1.3 1 1 0 1 1 1 0 APOBEC-like N-terminal domain WD40 PF00400.27 KKK22629.1 - 4.3e-05 23.2 0.2 0.069 13.0 0.0 3.2 3 0 0 3 3 3 2 WD domain, G-beta repeat Biopterin_H PF00351.16 KKK22629.1 - 0.13 10.9 0.0 0.2 10.3 0.0 1.2 1 0 0 1 1 1 0 Biopterin-dependent aromatic amino acid hydroxylase Vps53_N PF04100.7 KKK22630.1 - 3e-108 362.0 3.5 3.1e-108 361.9 1.0 1.9 2 0 0 2 2 2 1 Vps53-like, N-terminal Sec6 PF06046.8 KKK22630.1 - 5.5e-10 37.9 1.4 9.2e-09 33.9 0.0 2.8 2 1 0 2 2 2 1 Exocyst complex component Sec6 DUF2450 PF10475.4 KKK22630.1 - 1.2e-08 34.1 6.7 2.5e-08 33.1 4.7 1.4 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) COG2 PF06148.6 KKK22630.1 - 1.5e-06 28.1 2.0 5.6e-06 26.2 1.3 2.1 2 0 0 2 2 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Spc7 PF08317.6 KKK22630.1 - 1.5e-06 27.1 5.3 2.7e-06 26.2 3.7 1.4 1 0 0 1 1 1 1 Spc7 kinetochore protein RINT1_TIP1 PF04437.8 KKK22630.1 - 7.4e-05 21.4 1.4 0.00032 19.3 0.0 2.4 2 0 0 2 2 2 1 RINT-1 / TIP-1 family IncA PF04156.9 KKK22630.1 - 0.00042 19.9 6.3 0.002 17.7 4.4 2.2 1 0 0 1 1 1 1 IncA protein DUF2451 PF10474.4 KKK22630.1 - 0.0014 18.4 0.5 0.0057 16.4 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function C-terminus (DUF2451) Sigma70_ner PF04546.8 KKK22630.1 - 0.0036 16.9 6.7 0.026 14.1 3.4 2.3 2 0 0 2 2 2 1 Sigma-70, non-essential region Transposase_22 PF02994.9 KKK22630.1 - 0.005 15.3 2.1 0.0095 14.4 1.4 1.3 1 0 0 1 1 1 1 L1 transposable element DUF1515 PF07439.6 KKK22630.1 - 0.13 12.1 2.2 0.36 10.6 1.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) DUF342 PF03961.8 KKK22630.1 - 0.14 10.5 1.2 0.24 9.7 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) V_ATPase_I PF01496.14 KKK22630.1 - 0.39 8.5 2.9 0.59 7.9 2.0 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Reo_sigmaC PF04582.7 KKK22630.1 - 1.6 7.8 10.2 0.073 12.2 1.8 2.2 2 0 0 2 2 2 0 Reovirus sigma C capsid protein URO-D PF01208.12 KKK22631.1 - 2.2e-120 401.7 0.0 4.3e-118 394.1 0.0 2.0 1 1 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) PP1 PF07430.6 KKK22631.1 - 0.061 12.9 0.0 0.15 11.6 0.0 1.6 1 0 0 1 1 1 0 Phloem filament protein PP1 Ribosomal_L10 PF00466.15 KKK22632.1 - 1.2e-26 92.5 0.3 2.4e-26 91.5 0.2 1.5 1 0 0 1 1 1 1 Ribosomal protein L10 Ribosomal_60s PF00428.14 KKK22632.1 - 4.5e-22 78.2 4.1 4.5e-22 78.2 2.9 2.1 2 0 0 2 2 2 1 60s Acidic ribosomal protein PH PF00169.24 KKK22633.1 - 1.2e-05 25.4 0.0 0.00044 20.4 0.0 2.6 2 0 0 2 2 2 1 PH domain PH_9 PF15410.1 KKK22633.1 - 0.0028 17.7 0.0 0.0088 16.2 0.0 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain LRR_4 PF12799.2 KKK22635.1 - 8.7e-09 34.8 0.0 8.8e-05 22.0 0.0 2.5 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) NTF2 PF02136.15 KKK22635.1 - 6.2e-07 29.8 0.0 1.8e-06 28.2 0.0 1.9 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain LRR_8 PF13855.1 KKK22635.1 - 6.6e-05 22.5 0.0 0.00013 21.6 0.0 1.5 1 0 0 1 1 1 1 Leucine rich repeat LRR_1 PF00560.28 KKK22635.1 - 0.00034 20.2 0.0 3.2 8.1 0.0 3.3 3 0 0 3 3 3 2 Leucine Rich Repeat LRR_6 PF13516.1 KKK22635.1 - 0.0031 17.3 0.1 0.49 10.6 0.0 3.4 4 0 0 4 4 4 1 Leucine Rich repeat LRR_7 PF13504.1 KKK22635.1 - 0.0056 16.6 0.3 3.2 8.3 0.1 3.3 2 0 0 2 2 2 1 Leucine rich repeat LRR_9 PF14580.1 KKK22635.1 - 0.0064 16.0 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 Leucine-rich repeat TAP_C PF03943.8 KKK22635.1 - 0.02 14.2 0.8 0.02 14.2 0.6 1.7 2 0 0 2 2 2 0 TAP C-terminal domain Coatamer_beta_C PF07718.7 KKK22635.1 - 0.13 11.8 0.0 0.28 10.8 0.0 1.5 1 0 0 1 1 1 0 Coatomer beta C-terminal region COPIIcoated_ERV PF07970.7 KKK22636.1 - 8.3e-71 238.1 0.0 7.2e-47 159.8 0.0 2.6 2 1 1 3 3 3 2 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 KKK22636.1 - 6.3e-34 115.8 0.0 1.4e-33 114.7 0.0 1.6 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) G-gamma PF00631.17 KKK22637.1 - 1.3e-25 88.8 0.0 1.6e-25 88.6 0.0 1.1 1 0 0 1 1 1 1 GGL domain DUF3220 PF11516.3 KKK22637.1 - 0.051 13.5 0.0 0.069 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3120) RSS_P20 PF11757.3 KKK22637.1 - 0.1 12.7 0.0 0.13 12.4 0.0 1.1 1 0 0 1 1 1 0 Suppressor of RNA silencing P21-like Rdx PF10262.4 KKK22639.1 - 6.9e-29 99.6 0.0 9.1e-29 99.3 0.0 1.2 1 0 0 1 1 1 1 Rdx family TCRP1 PF14944.1 KKK22639.1 - 0.0067 16.3 0.2 0.011 15.7 0.1 1.2 1 0 0 1 1 1 1 Tongue Cancer Chemotherapy Resistant Protein 1 Serglycin PF04360.7 KKK22639.1 - 0.04 13.6 0.2 0.049 13.3 0.1 1.3 1 0 0 1 1 1 0 Serglycin DUF1168 PF06658.7 KKK22639.1 - 8.6 5.8 6.7 16 4.9 4.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) PDEase_I PF00233.14 KKK22640.1 - 3.7e-47 161.0 0.0 4.8e-42 144.3 0.0 2.2 2 0 0 2 2 2 2 3'5'-cyclic nucleotide phosphodiesterase HD PF01966.17 KKK22640.1 - 0.047 13.6 0.0 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 HD domain Acetyltransf_1 PF00583.19 KKK22641.1 - 5e-11 42.4 0.1 7.1e-11 41.9 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 KKK22641.1 - 2.6e-05 23.9 0.0 4.4e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 KKK22641.1 - 0.0011 19.0 0.0 0.0016 18.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KKK22641.1 - 0.014 15.5 0.0 0.027 14.6 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KKK22641.1 - 0.13 12.1 0.2 0.24 11.2 0.1 1.6 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain MFS_1 PF07690.11 KKK22642.1 - 3.4e-22 78.6 52.0 4.1e-19 68.4 23.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily PCI PF01399.22 KKK22643.1 - 1.2e-10 41.6 2.4 7.3e-10 39.0 0.0 3.3 3 0 0 3 3 3 1 PCI domain RNA_pol_Rpb6 PF01192.17 KKK22644.1 - 1.4e-24 85.5 0.2 2.7e-24 84.6 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb6 zf-C2H2 PF00096.21 KKK22645.1 - 2.4e-27 93.5 61.9 0.00036 20.7 0.2 11.3 10 2 0 10 10 10 10 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KKK22645.1 - 1.4e-24 84.5 57.0 0.0038 17.4 0.0 10.8 10 0 0 10 10 10 9 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KKK22645.1 - 1.7e-19 69.0 54.2 5.6e-05 23.2 0.5 11.0 11 0 0 11 11 11 7 Zinc-finger double domain zf-C2H2_jaz PF12171.3 KKK22645.1 - 0.0034 17.4 18.1 18 5.6 0.0 8.4 10 0 0 10 10 10 1 Zinc-finger double-stranded RNA-binding GAGA PF09237.6 KKK22645.1 - 0.31 10.6 4.8 0.3 10.7 1.1 2.6 2 0 0 2 2 2 0 GAGA factor Sulfate_transp PF00916.15 KKK22646.1 - 8.3e-75 251.3 10.2 1.5e-74 250.5 7.0 1.4 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 KKK22646.1 - 6.9e-32 108.9 3.3 6.9e-32 108.9 2.3 3.2 3 0 0 3 3 3 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 KKK22646.1 - 4.6e-08 32.4 0.0 9.1e-08 31.5 0.0 1.4 1 0 0 1 1 1 1 STAS domain DUF457 PF04307.9 KKK22646.1 - 0.0039 16.5 3.7 0.016 14.5 2.6 2.2 1 0 0 1 1 1 1 Predicted membrane-bound metal-dependent hydrolase (DUF457) SNN_transmemb PF09049.5 KKK22646.1 - 1.9 8.2 9.4 0.041 13.5 0.8 2.7 2 0 0 2 2 2 0 Stannin transmembrane Ribosomal_L12 PF00542.14 KKK22655.1 - 6.1e-19 67.7 10.7 1.2e-17 63.6 5.9 2.2 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain HisG_C PF08029.6 KKK22655.1 - 0.013 15.3 0.2 0.041 13.8 0.1 1.9 1 1 0 1 1 1 0 HisG, C-terminal domain FliG_N PF14842.1 KKK22655.1 - 0.022 14.8 1.0 0.032 14.3 0.2 1.6 2 0 0 2 2 2 0 FliG N-terminal domain GHMP_kinases_C PF08544.8 KKK22655.1 - 0.033 14.3 3.8 3.4 7.9 0.9 3.2 2 2 0 2 2 2 0 GHMP kinases C terminal Ribosomal_60s PF00428.14 KKK22655.1 - 0.89 10.0 9.7 0.054 13.9 1.0 2.6 3 0 0 3 3 3 0 60s Acidic ribosomal protein Alpha-amylase PF00128.19 KKK22656.1 - 2.1e-71 240.9 1.7 2.8e-71 240.5 1.2 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.6 KKK22656.1 - 6.4e-33 112.6 0.1 1.3e-32 111.7 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) Glyco_hydro_31 PF01055.21 KKK22656.1 - 2.9e-05 23.1 0.5 3.4e-05 22.8 0.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Homeobox_KN PF05920.6 KKK22657.1 - 5.8e-20 70.7 0.4 5.8e-20 70.7 0.3 2.0 2 0 0 2 2 2 1 Homeobox KN domain Homeobox PF00046.24 KKK22657.1 - 3.5e-07 29.7 0.1 6.2e-07 28.9 0.1 1.4 1 0 0 1 1 1 1 Homeobox domain AA_permease_2 PF13520.1 KKK22658.1 - 4.9e-52 176.8 51.0 6.2e-52 176.5 35.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KKK22658.1 - 9.9e-24 83.5 46.6 1.3e-23 83.0 32.3 1.0 1 0 0 1 1 1 1 Amino acid permease FixP_N PF14715.1 KKK22658.1 - 6 6.3 6.0 19 4.7 1.2 3.2 2 0 0 2 2 2 0 N-terminal domain of cytochrome oxidase-cbb3, FixP APH PF01636.18 KKK22659.1 - 2.3e-13 50.4 0.5 1.4e-12 47.8 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Glyco_hydro_47 PF01532.15 KKK22660.1 - 3e-178 593.1 0.0 3.4e-178 592.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DUF1680 PF07944.7 KKK22660.1 - 0.027 12.7 0.0 1.4 7.0 0.0 2.1 2 0 0 2 2 2 0 Putative glycosyl hydrolase of unknown function (DUF1680) Lysis_S PF04971.7 KKK22661.1 - 0.23 11.1 1.1 0.6 9.8 0.2 2.2 2 0 0 2 2 2 0 Lysis protein S Med20 PF08612.6 KKK22662.1 - 3.3e-95 317.5 0.0 3.7e-95 317.3 0.0 1.0 1 0 0 1 1 1 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex EF-hand_1 PF00036.27 KKK22663.1 - 3.1e-41 135.5 11.5 1.1e-09 36.9 0.6 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 KKK22663.1 - 9.2e-37 125.0 5.9 6.4e-20 71.0 1.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 KKK22663.1 - 1.5e-34 117.3 11.8 6.8e-16 57.6 0.5 4.0 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.1 KKK22663.1 - 1.5e-30 102.3 6.8 3.4e-09 35.8 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 KKK22663.1 - 1.8e-26 90.2 7.7 1.9e-06 26.9 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 KKK22663.1 - 1.2e-15 57.0 0.3 2.2e-08 33.9 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 KKK22663.1 - 5.1e-10 39.0 1.5 0.00063 19.4 0.2 2.1 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 KKK22663.1 - 1.6e-08 34.5 0.0 0.0038 17.2 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.8 KKK22663.1 - 3.2e-08 33.0 0.1 0.022 14.3 0.0 3.2 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.5 KKK22663.1 - 5.8e-07 29.3 2.4 4.5e-06 26.5 0.2 2.3 2 1 0 2 2 2 1 Ca2+ insensitive EF hand TerB PF05099.8 KKK22663.1 - 0.00015 21.5 0.3 0.32 10.7 0.0 2.2 1 1 1 2 2 2 2 Tellurite resistance protein TerB Caleosin PF05042.8 KKK22663.1 - 0.0004 19.9 0.1 0.064 12.8 0.1 2.7 1 1 0 1 1 1 1 Caleosin related protein Tenui_NCP PF04876.7 KKK22663.1 - 0.0025 17.3 0.1 0.13 11.8 0.0 2.3 1 1 1 2 2 2 1 Tenuivirus major non-capsid protein RNA_pol_Rpb4 PF03874.11 KKK22663.1 - 0.0027 17.6 0.7 1.3 9.0 0.0 2.6 3 0 0 3 3 3 2 RNA polymerase Rpb4 Toprim_2 PF13155.1 KKK22663.1 - 0.0059 16.9 1.4 1.8 8.9 0.0 2.5 1 1 1 2 2 2 2 Toprim-like DUF3349 PF11829.3 KKK22663.1 - 0.025 14.9 0.4 8.4 6.8 0.1 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF3349) EF-hand_10 PF14788.1 KKK22663.1 - 0.14 11.8 2.4 0.84 9.3 0.1 3.1 1 1 3 4 4 4 0 EF hand RloB PF13707.1 KKK22663.1 - 0.28 10.8 4.1 0.59 9.7 0.3 2.3 1 1 1 2 2 2 0 RloB-like protein PB1 PF00564.19 KKK22663.1 - 0.43 10.2 2.8 35 4.1 0.0 3.3 2 1 1 3 3 3 0 PB1 domain DUF2404 PF10296.4 KKK22664.1 - 0.12 12.5 0.0 0.38 10.8 0.0 1.8 2 0 0 2 2 2 0 Putative integral membrane protein conserved region (DUF2404) CDC37_N PF03234.9 KKK22665.1 - 2.5e-61 207.0 5.7 2.5e-61 207.0 4.0 2.7 2 1 1 3 3 3 1 Cdc37 N terminal kinase binding CDC37_M PF08565.6 KKK22665.1 - 2.2e-49 167.2 0.3 7.2e-49 165.5 0.2 1.9 1 0 0 1 1 1 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.5 KKK22665.1 - 2.5e-27 94.6 1.6 9.9e-27 92.7 1.1 2.0 1 0 0 1 1 1 1 Cdc37 C terminal domain DUF3887 PF13026.1 KKK22665.1 - 0.062 13.5 0.4 0.062 13.5 0.2 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3887) DUF1682 PF07946.9 KKK22666.1 - 1.2e-113 379.2 2.2 1.4e-113 379.0 1.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) ABC_membrane PF00664.18 KKK22667.1 - 1.4e-42 146.0 10.1 1.7e-42 145.7 7.0 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 KKK22667.1 - 2.7e-35 121.6 0.0 6.8e-35 120.3 0.0 1.7 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 KKK22667.1 - 6.1e-05 23.1 0.0 0.27 11.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.14 KKK22667.1 - 0.00044 19.5 0.8 0.027 13.7 0.6 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 KKK22667.1 - 0.0024 17.3 0.0 0.0068 15.9 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.1 KKK22667.1 - 0.0044 17.1 0.1 0.018 15.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KKK22667.1 - 0.0076 17.0 0.0 0.016 15.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 KKK22667.1 - 0.012 15.0 0.1 0.2 11.0 0.0 2.6 2 1 1 3 3 3 0 IstB-like ATP binding protein ABC_ATPase PF09818.4 KKK22667.1 - 0.012 14.2 0.4 0.052 12.1 0.1 1.9 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_16 PF13191.1 KKK22667.1 - 0.016 15.2 0.7 0.1 12.5 0.5 2.2 1 1 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.1 KKK22667.1 - 0.035 13.5 0.2 0.16 11.3 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.24 KKK22667.1 - 0.047 13.8 0.0 0.24 11.5 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SbcCD_C PF13558.1 KKK22667.1 - 0.061 13.2 2.6 0.14 12.0 0.4 2.7 2 1 0 2 2 1 0 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.1 KKK22667.1 - 0.092 13.0 0.1 0.23 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 KKK22667.1 - 0.1 11.8 0.0 0.22 10.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 MobB PF03205.9 KKK22667.1 - 0.13 11.9 0.0 0.3 10.8 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Nucleoside_tran PF01733.13 KKK22668.1 - 1e-47 162.7 12.6 1e-47 162.7 8.7 2.5 2 1 0 2 2 2 1 Nucleoside transporter DUF3635 PF12330.3 KKK22669.1 - 5.5e-06 26.3 0.0 1.5e-05 24.9 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3635) SNARE PF05739.14 KKK22670.1 - 3.5e-18 65.0 3.0 1.1e-17 63.4 2.1 1.9 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.20 KKK22670.1 - 8.4e-12 45.1 2.9 1.4e-11 44.4 0.2 2.3 2 0 0 2 2 2 1 Syntaxin DUF948 PF06103.6 KKK22670.1 - 0.53 10.1 2.8 4.9 7.0 0.0 3.0 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) MCPsignal PF00015.16 KKK22670.1 - 0.56 9.7 8.8 0.14 11.6 1.3 2.4 2 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain SlyX PF04102.7 KKK22670.1 - 0.62 10.4 8.6 5.1 7.5 0.2 3.4 3 1 1 4 4 4 0 SlyX Syntaxin_2 PF14523.1 KKK22670.1 - 2.1 8.4 11.2 1.9 8.5 0.3 3.1 2 1 1 3 3 3 0 Syntaxin-like protein CTD_bind PF04818.8 KKK22671.1 - 3.3e-21 75.2 0.4 6.3e-21 74.3 0.3 1.5 1 0 0 1 1 1 1 RNA polymerase II-binding domain. DUF3277 PF11681.3 KKK22671.1 - 0.048 13.1 0.0 0.094 12.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3277) Clathrin_lg_ch PF01086.12 KKK22672.1 - 3.7e-73 246.1 1.9 4.1e-73 246.0 1.3 1.0 1 0 0 1 1 1 1 Clathrin light chain MFMR PF07777.6 KKK22672.1 - 0.038 13.9 0.4 0.061 13.2 0.3 1.2 1 0 0 1 1 1 0 G-box binding protein MFMR zf-DHHC PF01529.15 KKK22693.1 - 0.055 12.8 1.5 0.28 10.5 0.2 2.1 2 0 0 2 2 2 0 DHHC palmitoyltransferase Tim54 PF11711.3 KKK22693.1 - 0.12 10.9 1.4 0.22 10.0 1.0 1.4 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Yippee-Mis18 PF03226.9 KKK22693.1 - 0.13 12.3 0.1 5.5 7.0 0.0 2.3 2 0 0 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Pex14_N PF04695.8 KKK22693.1 - 0.2 11.6 2.9 1.9 8.5 0.1 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region EF-hand_7 PF13499.1 KKK22694.1 - 2e-12 47.0 0.0 3.2e-08 33.5 0.0 2.1 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 KKK22694.1 - 9.8e-11 40.6 0.1 0.0017 18.0 0.0 3.6 4 0 0 4 4 4 2 EF-hand domain EF-hand_9 PF14658.1 KKK22694.1 - 8.9e-10 38.3 0.0 0.00014 21.7 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 KKK22694.1 - 2.8e-08 32.4 0.0 0.056 12.7 0.0 3.7 3 1 0 3 3 3 2 EF hand EF-hand_8 PF13833.1 KKK22694.1 - 5.9e-07 29.0 0.1 0.00047 19.7 0.0 3.3 2 1 1 3 3 3 2 EF-hand domain pair DUF3216 PF11505.3 KKK22694.1 - 0.064 13.0 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3216) UPF0154 PF03672.8 KKK22694.1 - 0.075 12.6 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0154) EF-hand_5 PF13202.1 KKK22694.1 - 0.14 11.5 0.6 4.2 6.8 0.2 2.7 2 0 0 2 2 2 0 EF hand Xan_ur_permease PF00860.15 KKK22695.1 - 4.4e-64 216.3 32.2 1.9e-63 214.2 22.3 1.8 1 1 0 1 1 1 1 Permease family FA_desaturase PF00487.19 KKK22696.1 - 2.2e-19 69.9 11.4 2.2e-19 69.9 7.9 1.6 2 0 0 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.23 KKK22696.1 - 8.8e-18 63.8 0.1 2.1e-17 62.6 0.1 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Rad51 PF08423.6 KKK22697.1 - 1.1e-10 40.8 0.0 6.4e-09 35.0 0.0 2.2 1 1 0 1 1 1 1 Rad51 AAA_25 PF13481.1 KKK22697.1 - 1.5e-08 34.2 0.0 5.4e-06 25.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain RecA PF00154.16 KKK22697.1 - 3.3e-06 26.3 0.0 5.9e-05 22.2 0.0 2.2 2 0 0 2 2 2 1 recA bacterial DNA recombination protein AAA_10 PF12846.2 KKK22697.1 - 3.4e-06 26.7 0.0 4.1e-05 23.1 0.0 2.4 3 0 0 3 3 3 1 AAA-like domain KaiC PF06745.8 KKK22697.1 - 4.6e-06 25.9 0.0 9.8e-06 24.8 0.0 1.6 1 0 0 1 1 1 1 KaiC IstB_IS21 PF01695.12 KKK22697.1 - 9.9e-06 25.0 0.0 1.9e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_22 PF13401.1 KKK22697.1 - 2.5e-05 24.4 0.0 8.8e-05 22.6 0.0 1.8 1 1 1 2 2 2 1 AAA domain AAA PF00004.24 KKK22697.1 - 0.00018 21.6 0.1 0.00057 20.0 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DnaB_C PF03796.10 KKK22697.1 - 0.00037 19.4 0.0 0.015 14.2 0.0 2.2 2 0 0 2 2 2 1 DnaB-like helicase C terminal domain AAA_24 PF13479.1 KKK22697.1 - 0.0011 18.5 0.0 0.012 15.1 0.1 2.2 1 1 1 2 2 2 1 AAA domain CbiA PF01656.18 KKK22697.1 - 0.0013 18.1 0.0 0.0026 17.1 0.0 1.6 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_19 PF13245.1 KKK22697.1 - 0.0017 18.0 0.4 0.0039 16.9 0.1 1.8 2 0 0 2 2 1 1 Part of AAA domain Arch_ATPase PF01637.13 KKK22697.1 - 0.0018 18.0 0.0 0.0026 17.5 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase AAA_17 PF13207.1 KKK22697.1 - 0.0023 18.7 0.0 0.012 16.4 0.0 2.1 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 KKK22697.1 - 0.01 14.9 0.0 0.017 14.1 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 KKK22697.1 - 0.011 15.7 0.0 0.036 14.0 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain RNA_helicase PF00910.17 KKK22697.1 - 0.017 15.2 0.1 0.37 10.9 0.0 2.5 2 1 0 2 2 2 0 RNA helicase APS_kinase PF01583.15 KKK22697.1 - 0.022 14.4 0.1 1.1 8.8 0.0 2.3 2 0 0 2 2 2 0 Adenylylsulphate kinase NB-ARC PF00931.17 KKK22697.1 - 0.038 12.8 0.0 0.066 12.0 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_33 PF13671.1 KKK22697.1 - 0.047 13.5 0.0 0.14 11.9 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.1 KKK22697.1 - 0.054 13.8 0.0 0.15 12.3 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_35 PF14516.1 KKK22697.1 - 0.076 11.6 0.0 0.13 10.8 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain ABC_tran PF00005.22 KKK22697.1 - 0.076 13.3 0.0 0.19 12.0 0.0 1.6 1 1 0 1 1 1 0 ABC transporter AAA_31 PF13614.1 KKK22697.1 - 0.079 12.8 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 KKK22697.1 - 0.1 11.8 0.0 0.2 10.8 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein MOSC PF03473.12 KKK22698.1 - 1.1e-11 44.3 0.1 2.1e-09 36.9 0.0 2.5 2 0 0 2 2 2 2 MOSC domain MOSC_N PF03476.11 KKK22698.1 - 1.6e-09 37.5 0.0 4.3e-09 36.1 0.0 1.7 1 1 0 1 1 1 1 MOSC N-terminal beta barrel domain 5-FTHF_cyc-lig PF01812.15 KKK22700.1 - 4.9e-18 65.5 0.0 6.4e-18 65.1 0.0 1.2 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family LSM PF01423.17 KKK22701.1 - 1.4e-14 53.3 0.1 1.7e-14 53.1 0.0 1.1 1 0 0 1 1 1 1 LSM domain YqeY PF09424.5 KKK22702.1 - 2.7e-19 69.4 1.5 3.2e-19 69.1 1.0 1.2 1 0 0 1 1 1 1 Yqey-like protein Cellulase PF00150.13 KKK22702.1 - 0.016 14.4 0.0 0.035 13.3 0.0 1.5 2 0 0 2 2 2 0 Cellulase (glycosyl hydrolase family 5) ParcG PF10274.4 KKK22702.1 - 0.029 14.2 0.0 0.037 13.9 0.0 1.2 1 0 0 1 1 1 0 Parkin co-regulated protein Rot1 PF10681.4 KKK22703.1 - 5.9e-89 297.0 0.0 6.7e-89 296.8 0.0 1.0 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal TauD PF02668.11 KKK22704.1 - 1.6e-46 159.0 0.0 2.1e-46 158.7 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family LCD1 PF09798.4 KKK22704.1 - 0.065 11.2 0.0 0.09 10.7 0.0 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein Nucleoporin_C PF03177.9 KKK22705.1 - 1.4e-137 459.7 5.2 1.8e-137 459.3 3.6 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 KKK22705.1 - 6.1e-87 292.0 0.1 8.5e-87 291.6 0.0 1.2 1 0 0 1 1 1 1 Nup133 N terminal like Xpo1 PF08389.7 KKK22706.1 - 8.6e-23 80.8 0.0 9.2e-22 77.5 0.0 2.9 3 0 0 3 3 3 1 Exportin 1-like protein IBN_N PF03810.14 KKK22706.1 - 0.00015 21.5 0.5 0.0023 17.8 0.0 2.6 2 0 0 2 2 2 1 Importin-beta N-terminal domain HEAT_2 PF13646.1 KKK22706.1 - 0.054 13.7 0.0 0.28 11.5 0.0 2.3 1 0 0 1 1 1 0 HEAT repeats HEAT PF02985.17 KKK22706.1 - 0.079 13.0 0.3 12 6.2 0.0 4.1 3 0 0 3 3 3 0 HEAT repeat HEAT_EZ PF13513.1 KKK22706.1 - 0.08 13.4 1.5 0.88 10.1 0.0 3.9 4 0 0 4 4 4 0 HEAT-like repeat Adaptin_N PF01602.15 KKK22706.1 - 0.12 10.6 0.6 0.52 8.5 0.1 2.0 2 0 0 2 2 2 0 Adaptin N terminal region Fungal_trans PF04082.13 KKK22707.1 - 6.4e-64 215.3 0.1 8.7e-64 214.8 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 KKK22707.1 - 3.1e-05 24.0 12.0 0.00073 19.7 1.1 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KKK22707.1 - 0.00039 20.5 11.5 0.0011 19.0 0.9 3.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KKK22707.1 - 0.019 15.2 10.9 0.051 13.8 1.5 2.7 2 0 0 2 2 2 0 Zinc-finger double domain Pkinase PF00069.20 KKK22741.1 - 3.9e-69 232.7 0.0 5.7e-69 232.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK22741.1 - 3.3e-32 111.5 0.0 4.8e-32 111.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 KKK22741.1 - 1.3e-10 41.1 0.4 5e-10 39.3 0.1 2.2 3 0 0 3 3 3 1 FHA domain Kinase-like PF14531.1 KKK22741.1 - 0.00054 19.0 0.0 0.0011 17.9 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.9 KKK22741.1 - 0.0029 16.6 0.1 0.0051 15.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KKK22741.1 - 0.011 15.4 0.1 6.1 6.4 0.0 3.0 2 1 1 3 3 3 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 KKK22741.1 - 0.073 11.8 0.1 0.12 11.1 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Glyco_transf_34 PF05637.7 KKK22742.1 - 7.3e-60 202.4 0.7 1.1e-59 201.9 0.5 1.1 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family NDUFB10 PF10249.4 KKK22743.1 - 0.026 14.6 0.0 0.028 14.5 0.0 1.0 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase subunit 10 Cecropin PF00272.14 KKK22743.1 - 0.16 11.5 0.3 0.31 10.6 0.2 1.5 1 0 0 1 1 1 0 Cecropin family Glutaredoxin PF00462.19 KKK22744.1 - 2.3e-18 65.9 0.0 7.7e-17 61.0 0.0 2.5 2 1 0 2 2 2 1 Glutaredoxin Thioredoxin PF00085.15 KKK22744.1 - 8.4e-15 54.3 0.0 2.4e-14 52.8 0.0 1.7 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_8 PF13905.1 KKK22744.1 - 0.00035 20.6 0.0 0.0016 18.4 0.0 2.0 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_2 PF13098.1 KKK22744.1 - 0.043 14.0 0.0 1.5 9.0 0.0 3.0 2 2 1 3 3 3 0 Thioredoxin-like domain RNase_T PF00929.19 KKK22745.1 - 2.1e-26 93.1 0.0 3.3e-26 92.5 0.0 1.3 1 0 0 1 1 1 1 Exonuclease Ribosomal_60s PF00428.14 KKK22745.1 - 1.1 9.7 6.9 51 4.3 3.5 2.6 2 0 0 2 2 2 0 60s Acidic ribosomal protein Yippee-Mis18 PF03226.9 KKK22746.1 - 0.066 13.2 1.1 0.15 12.1 0.8 1.6 1 0 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Beta_elim_lyase PF01212.16 KKK22747.1 - 1.5e-68 231.0 0.0 1.8e-68 230.7 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase OKR_DC_1 PF01276.15 KKK22747.1 - 0.0056 15.2 0.0 0.0084 14.6 0.0 1.1 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain CAF1A PF12253.3 KKK22752.1 - 1.7e-25 88.9 7.3 1.7e-25 88.9 5.1 3.5 2 1 0 2 2 2 1 Chromatin assembly factor 1 subunit A CAF-1_p150 PF11600.3 KKK22752.1 - 1.3e-06 27.9 78.8 1.3e-06 27.9 54.6 2.4 2 1 1 3 3 3 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal MIP-T3 PF10243.4 KKK22752.1 - 3.7e-06 25.7 33.1 3.7e-06 25.7 22.9 1.6 2 0 0 2 2 2 1 Microtubule-binding protein MIP-T3 TFIIF_alpha PF05793.7 KKK22752.1 - 0.0015 17.0 29.0 0.0015 17.0 20.1 2.2 2 0 0 2 2 2 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) LMBR1 PF04791.11 KKK22752.1 - 0.68 8.4 7.7 0.93 8.0 5.3 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein Raftlin PF15250.1 KKK22752.1 - 3 6.2 17.8 4.8 5.6 10.8 2.0 2 0 0 2 2 2 0 Raftlin GAGA_bind PF06217.7 KKK22752.1 - 8.1 6.3 27.6 54 3.6 19.2 2.1 1 1 0 1 1 1 0 GAGA binding protein-like family IPP-2 PF04979.9 KKK22754.1 - 9.4e-11 42.0 12.6 8.2e-07 29.3 0.5 2.5 2 0 0 2 2 2 2 Protein phosphatase inhibitor 2 (IPP-2) TraC PF07820.7 KKK22755.1 - 0.13 12.4 0.0 1.7 8.9 0.0 2.5 2 0 0 2 2 2 0 TraC-like protein GFO_IDH_MocA PF01408.17 KKK22757.1 - 6e-25 88.0 0.0 9.5e-25 87.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 KKK22757.1 - 2e-16 59.7 0.0 3.6e-16 58.9 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.11 KKK22757.1 - 0.00018 21.8 0.0 0.00035 20.9 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain DapB_N PF01113.15 KKK22757.1 - 0.00053 19.8 0.0 0.00092 19.1 0.0 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Saccharop_dh PF03435.13 KKK22757.1 - 0.068 12.1 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase HPP PF04982.8 KKK22758.1 - 2.5e-34 117.6 11.8 2.5e-34 117.6 8.2 1.4 2 0 0 2 2 2 1 HPP family Ycf66_N PF07444.6 KKK22758.1 - 0.073 12.7 3.1 0.28 10.9 0.3 2.6 2 0 0 2 2 2 0 Ycf66 protein N-terminus DUF939 PF06081.6 KKK22758.1 - 0.82 9.5 8.0 2 8.2 5.6 1.6 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF939) Glyco_hydro_3 PF00933.16 KKK22759.1 - 7.5e-69 231.9 0.0 9.9e-69 231.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KKK22759.1 - 9.2e-62 208.5 0.0 1.4e-61 207.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KKK22759.1 - 8.7e-21 73.6 1.2 8.7e-21 73.6 0.8 1.9 2 0 0 2 2 2 1 Fibronectin type III-like domain Sugar-bind PF04198.8 KKK22759.1 - 0.11 11.4 0.0 0.19 10.5 0.0 1.3 1 0 0 1 1 1 0 Putative sugar-binding domain Med30 PF11315.3 KKK22760.1 - 0.032 14.3 0.1 4.8 7.2 0.0 2.5 2 0 0 2 2 2 0 Mediator complex subunit 30 Rootletin PF15035.1 KKK22760.1 - 0.18 11.7 11.9 11 5.9 8.8 2.7 2 1 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion HALZ PF02183.13 KKK22760.1 - 0.34 10.6 4.5 1.7 8.4 0.7 2.5 2 0 0 2 2 2 0 Homeobox associated leucine zipper DUF972 PF06156.8 KKK22760.1 - 0.35 11.2 3.0 19 5.6 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF972) WD40 PF00400.27 KKK22761.1 - 1.4e-20 72.2 17.2 3.9e-07 29.7 0.9 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat CDC45 PF02724.9 KKK22761.1 - 2.9 5.7 9.0 4.3 5.2 6.2 1.2 1 0 0 1 1 1 0 CDC45-like protein Mg_trans_NIPA PF05653.9 KKK22762.1 - 9.9e-44 149.4 9.7 3.1e-27 95.3 2.5 3.1 2 1 1 3 3 3 3 Magnesium transporter NIPA DUF4131 PF13567.1 KKK22762.1 - 3.7 6.9 6.9 0.74 9.1 0.8 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) BTP PF05232.7 KKK22762.1 - 4.4 7.1 7.0 9.9 5.9 0.4 2.8 2 0 0 2 2 2 0 Bacterial Transmembrane Pair family UQ_con PF00179.21 KKK22763.1 - 3.2e-43 146.5 0.0 4.1e-43 146.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.5 KKK22763.1 - 1.6e-07 30.8 1.2 3.2e-06 26.6 0.0 2.3 1 1 1 2 2 2 1 Fungal ubiquitin-associated domain Prok-E2_B PF14461.1 KKK22763.1 - 0.00027 20.7 0.0 0.00046 19.9 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 KKK22763.1 - 0.017 15.0 0.8 0.035 14.0 0.5 1.7 1 1 0 1 1 1 0 RWD domain AAA PF00004.24 KKK22764.1 - 4.8e-41 140.0 0.0 9.2e-41 139.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KKK22764.1 - 1.3e-07 31.8 0.1 5.1e-05 23.4 0.1 2.5 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 KKK22764.1 - 9.8e-06 25.5 0.0 2.1e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 KKK22764.1 - 1.1e-05 24.4 0.0 1.8e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.9 KKK22764.1 - 1.7e-05 24.5 0.0 5e-05 23.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KKK22764.1 - 0.00019 21.4 0.1 0.0014 18.6 0.1 2.1 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.7 KKK22764.1 - 0.0007 18.7 0.0 0.0013 17.8 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_28 PF13521.1 KKK22764.1 - 0.0027 17.7 1.3 0.0041 17.1 0.0 2.0 3 0 0 3 3 2 1 AAA domain AAA_14 PF13173.1 KKK22764.1 - 0.0027 17.6 0.0 0.0051 16.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KKK22764.1 - 0.0059 17.4 1.1 0.013 16.3 0.1 2.2 2 1 0 2 2 1 1 AAA domain IstB_IS21 PF01695.12 KKK22764.1 - 0.006 16.0 0.0 0.014 14.8 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein Zeta_toxin PF06414.7 KKK22764.1 - 0.0069 15.4 0.0 0.017 14.2 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin AAA_19 PF13245.1 KKK22764.1 - 0.007 16.0 0.3 0.016 14.9 0.2 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_33 PF13671.1 KKK22764.1 - 0.01 15.7 0.0 0.022 14.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 KKK22764.1 - 0.012 14.8 0.8 0.21 10.7 0.1 2.2 2 0 0 2 2 2 0 PhoH-like protein AAA_18 PF13238.1 KKK22764.1 - 0.014 15.7 0.0 0.035 14.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 KKK22764.1 - 0.014 15.0 0.1 0.35 10.5 0.1 2.3 1 1 0 2 2 2 0 NACHT domain AAA_3 PF07726.6 KKK22764.1 - 0.014 14.9 0.0 0.028 14.0 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 KKK22764.1 - 0.016 14.6 1.8 0.24 10.7 0.3 2.5 1 1 1 2 2 2 0 AAA domain TIP49 PF06068.8 KKK22764.1 - 0.017 13.8 0.2 0.046 12.4 0.1 1.7 1 1 0 1 1 1 0 TIP49 C-terminus NB-ARC PF00931.17 KKK22764.1 - 0.03 13.1 0.0 0.042 12.6 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain KaiC PF06745.8 KKK22764.1 - 0.033 13.3 0.2 0.47 9.5 0.1 2.2 1 1 0 2 2 2 0 KaiC RNA_helicase PF00910.17 KKK22764.1 - 0.038 14.1 0.0 0.087 13.0 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.1 KKK22764.1 - 0.047 13.2 0.1 0.13 11.8 0.1 1.7 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 KKK22764.1 - 0.053 12.6 0.1 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DUF2075 PF09848.4 KKK22764.1 - 0.13 11.1 0.0 0.2 10.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ABC_tran PF00005.22 KKK22765.1 - 1.3e-47 161.5 0.1 2.6e-22 79.6 0.0 2.7 3 0 0 3 3 2 2 ABC transporter ABC_tran_2 PF12848.2 KKK22765.1 - 2.1e-20 72.3 2.0 2.1e-20 72.3 1.4 2.9 3 0 0 3 3 2 1 ABC transporter AAA_21 PF13304.1 KKK22765.1 - 7.1e-19 68.8 0.8 0.00058 19.9 0.0 4.2 3 1 1 4 4 4 4 AAA domain SMC_N PF02463.14 KKK22765.1 - 7.3e-11 41.7 0.4 0.012 14.8 0.1 4.4 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 KKK22765.1 - 1.5e-08 35.2 3.2 0.031 14.6 0.0 3.6 4 0 0 4 4 3 2 AAA domain AAA_29 PF13555.1 KKK22765.1 - 1.7e-08 33.8 0.2 0.00063 19.2 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 KKK22765.1 - 2.6e-06 26.7 0.0 0.0031 16.6 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 KKK22765.1 - 8.4e-06 25.9 0.0 0.18 11.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain Miro PF08477.8 KKK22765.1 - 1.6e-05 25.3 0.0 0.035 14.6 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein AAA_16 PF13191.1 KKK22765.1 - 2.9e-05 24.1 0.3 0.14 12.1 0.0 3.0 2 1 0 2 2 2 2 AAA ATPase domain NACHT PF05729.7 KKK22765.1 - 3.5e-05 23.5 0.1 0.13 11.8 0.0 2.6 2 0 0 2 2 2 2 NACHT domain AAA_18 PF13238.1 KKK22765.1 - 4.5e-05 23.7 0.1 0.046 14.0 0.0 3.0 3 0 0 3 3 2 1 AAA domain NB-ARC PF00931.17 KKK22765.1 - 7.3e-05 21.7 0.0 0.06 12.1 0.0 3.1 2 1 0 2 2 2 1 NB-ARC domain MMR_HSR1 PF01926.18 KKK22765.1 - 7.7e-05 22.6 0.0 0.16 11.9 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase RNA_helicase PF00910.17 KKK22765.1 - 0.00017 21.7 0.5 1.6 8.9 0.0 3.3 3 0 0 3 3 3 2 RNA helicase AAA PF00004.24 KKK22765.1 - 0.0002 21.5 0.0 0.9 9.7 0.0 3.2 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 KKK22765.1 - 0.00024 20.8 0.0 0.23 11.0 0.0 2.9 3 0 0 3 3 3 1 Archaeal ATPase AAA_28 PF13521.1 KKK22765.1 - 0.0003 20.8 0.0 0.18 11.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KKK22765.1 - 0.00035 21.3 0.0 1.2 9.9 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA_33 PF13671.1 KKK22765.1 - 0.00041 20.2 1.2 0.31 10.9 0.0 3.2 4 0 0 4 4 3 1 AAA domain AAA_10 PF12846.2 KKK22765.1 - 0.00042 19.8 1.1 0.66 9.3 0.2 2.9 3 0 0 3 3 3 2 AAA-like domain AAA_14 PF13173.1 KKK22765.1 - 0.00044 20.1 0.0 1.1 9.1 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 KKK22765.1 - 0.0011 18.6 0.2 1.4 8.6 0.1 2.6 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_15 PF13175.1 KKK22765.1 - 0.0021 17.1 1.0 0.22 10.5 0.0 3.0 5 0 0 5 5 4 1 AAA ATPase domain MobB PF03205.9 KKK22765.1 - 0.0027 17.4 0.1 0.15 11.7 0.1 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B SbcCD_C PF13558.1 KKK22765.1 - 0.0027 17.5 0.4 0.29 11.0 0.0 3.3 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_25 PF13481.1 KKK22765.1 - 0.0038 16.6 0.0 0.96 8.8 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_13 PF13166.1 KKK22765.1 - 0.0042 15.6 0.2 5.3 5.3 0.0 3.3 3 1 0 3 3 3 0 AAA domain Dynamin_N PF00350.18 KKK22765.1 - 0.026 14.3 3.3 4.3 7.1 0.0 3.7 4 1 1 5 5 4 0 Dynamin family DAP3 PF10236.4 KKK22765.1 - 0.026 13.4 0.8 4.2 6.2 0.0 2.8 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 DUF87 PF01935.12 KKK22765.1 - 0.038 13.7 1.2 7.2 6.3 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function DUF87 ATP-synt_ab PF00006.20 KKK22765.1 - 0.039 13.4 0.0 0.35 10.3 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Ras PF00071.17 KKK22765.1 - 0.043 13.2 0.0 3.9 6.8 0.0 2.7 2 0 0 2 2 2 0 Ras family NTPase_1 PF03266.10 KKK22765.1 - 0.056 13.1 0.1 7.3 6.2 0.1 2.6 2 0 0 2 2 2 0 NTPase DUF2813 PF11398.3 KKK22765.1 - 0.076 12.0 2.1 6 5.8 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2813) FeoB_N PF02421.13 KKK22765.1 - 0.096 11.9 0.1 5 6.3 0.0 2.9 3 0 0 3 3 3 0 Ferrous iron transport protein B PduV-EutP PF10662.4 KKK22765.1 - 0.15 11.5 0.8 9.4 5.7 0.0 2.9 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.1 KKK22765.1 - 0.79 9.2 4.5 9.5 5.7 0.0 3.3 4 0 0 4 4 3 0 AAA domain Cyclin_N PF00134.18 KKK22766.1 - 1.2e-07 31.3 0.0 2.5e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Ribosomal_60s PF00428.14 KKK22766.1 - 1.1 9.6 4.6 3.7 8.0 0.4 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein Sugar_tr PF00083.19 KKK22767.1 - 6.5e-76 255.7 26.2 7.9e-76 255.4 18.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KKK22767.1 - 7.4e-18 64.3 50.1 1.5e-16 60.0 18.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily AAA_12 PF13087.1 KKK22768.1 - 1.2e-35 122.7 0.0 2.5e-35 121.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KKK22768.1 - 3.1e-29 102.2 0.5 1e-28 100.4 0.3 2.0 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KKK22768.1 - 9.6e-09 34.8 0.1 3.4e-08 33.1 0.1 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 KKK22768.1 - 3.3e-06 26.8 0.0 0.0011 18.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain DUF2075 PF09848.4 KKK22768.1 - 0.0016 17.4 0.1 0.033 13.1 0.0 2.4 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) ResIII PF04851.10 KKK22768.1 - 0.015 15.0 0.0 0.038 13.8 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit UvrD_C_2 PF13538.1 KKK22768.1 - 0.028 14.5 0.2 0.17 12.0 0.0 2.4 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain Zn_clus PF00172.13 KKK22769.1 - 1.5e-06 28.0 10.8 1.5e-06 28.0 7.5 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KKK22769.1 - 0.0014 17.3 0.0 0.0028 16.3 0.0 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Methyltransf_3 PF01596.12 KKK22770.1 - 8.4e-14 51.1 0.0 1.1e-13 50.7 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.1 KKK22770.1 - 6.4e-12 46.2 0.0 9.4e-12 45.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KKK22770.1 - 0.00087 19.3 0.2 0.0023 17.9 0.1 1.8 1 1 0 1 1 1 1 Methyltransferase domain CmcI PF04989.7 KKK22770.1 - 0.036 13.3 0.0 0.064 12.5 0.0 1.3 1 0 0 1 1 1 0 Cephalosporin hydroxylase DUF2119 PF09892.4 KKK22770.1 - 0.067 12.4 0.0 0.71 9.1 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2119) Ldh_1_N PF00056.18 KKK22771.1 - 8.9e-26 90.3 0.4 3.4e-23 82.0 0.3 2.2 1 1 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 KKK22771.1 - 2e-23 83.0 0.0 2.9e-23 82.4 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain F420_oxidored PF03807.12 KKK22771.1 - 0.0025 18.1 0.3 0.011 16.1 0.2 2.0 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Glyco_hydro_4 PF02056.11 KKK22771.1 - 0.021 14.1 0.0 0.041 13.1 0.0 1.6 1 1 0 1 1 1 0 Family 4 glycosyl hydrolase ThiF PF00899.16 KKK22771.1 - 0.046 13.5 0.2 0.1 12.4 0.1 1.5 1 0 0 1 1 1 0 ThiF family ApbA PF02558.11 KKK22771.1 - 0.11 11.9 0.2 0.37 10.2 0.2 1.8 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Malic_M PF03949.10 KKK22771.1 - 0.11 12.0 0.0 0.5 9.8 0.0 2.0 2 0 0 2 2 2 0 Malic enzyme, NAD binding domain Bot1p PF12298.3 KKK22783.1 - 1.2e-56 191.3 3.1 1.2e-56 191.3 2.2 2.1 1 1 1 2 2 2 1 Eukaryotic mitochondrial regulator protein Amidase PF01425.16 KKK22789.1 - 8.6e-98 328.0 0.0 1.1e-97 327.6 0.0 1.2 1 0 0 1 1 1 1 Amidase EAP30 PF04157.11 KKK22789.1 - 2.3e-53 180.6 0.0 3.3e-53 180.1 0.0 1.2 1 0 0 1 1 1 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.3 KKK22789.1 - 7.9e-16 57.6 0.0 1.6e-15 56.7 0.0 1.4 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 zf-Sec23_Sec24 PF04810.10 KKK22789.1 - 0.0021 17.5 1.0 0.0021 17.5 0.7 2.7 2 0 0 2 2 2 1 Sec23/Sec24 zinc finger zf-RanBP PF00641.13 KKK22789.1 - 0.0036 16.3 6.0 0.33 10.0 0.2 2.6 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others GRAM PF02893.15 KKK22789.1 - 0.13 11.8 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 GRAM domain zf-C2H2_4 PF13894.1 KKK22789.1 - 8.5 6.9 5.8 81 3.9 0.1 4.0 4 0 0 4 4 4 0 C2H2-type zinc finger Phosducin PF02114.11 KKK22794.1 - 1.5e-12 46.8 0.0 6.2e-10 38.2 0.0 2.1 2 0 0 2 2 2 2 Phosducin zf-MYND PF01753.13 KKK22795.1 - 2e-07 30.7 20.4 2e-07 30.7 14.2 1.7 2 0 0 2 2 2 1 MYND finger WD40 PF00400.27 KKK22796.1 - 1.7e-52 173.5 22.4 6.2e-09 35.3 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 KKK22796.1 - 2.8e-05 23.9 0.0 0.08 12.6 0.0 2.9 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A DSPc PF00782.15 KKK22818.1 - 4.9e-31 107.0 0.0 5.6e-23 80.9 0.0 2.2 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KKK22818.1 - 5.6e-06 25.8 0.0 0.00025 20.4 0.0 2.2 2 0 0 2 2 2 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 KKK22818.1 - 0.017 15.1 0.0 0.079 12.9 0.0 1.9 2 0 0 2 2 2 0 Inositol hexakisphosphate WD40 PF00400.27 KKK22820.1 - 4.1e-06 26.4 1.7 0.0031 17.3 0.0 4.0 4 0 0 4 4 4 1 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 KKK22820.1 - 0.00084 18.2 0.0 0.0045 15.8 0.0 2.0 2 0 0 2 2 2 1 Coatomer WD associated region CNH PF00780.17 KKK22820.1 - 0.0011 18.3 0.0 0.33 10.3 0.0 2.5 2 1 0 2 2 2 2 CNH domain Apc4_WD40 PF12894.2 KKK22820.1 - 0.05 13.1 0.0 9.7 5.7 0.0 3.0 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain RIO1 PF01163.17 KKK22821.1 - 3.7e-40 137.3 0.8 3.4e-28 98.2 0.0 2.5 2 0 0 2 2 2 2 RIO1 family Rio2_N PF09202.6 KKK22821.1 - 1.1e-31 108.7 0.0 3.4e-31 107.1 0.0 1.9 1 0 0 1 1 1 1 Rio2, N-terminal PC_rep PF01851.17 KKK22821.1 - 3.8e-17 61.4 12.6 0.0003 20.8 0.1 8.3 8 0 0 8 8 8 4 Proteasome/cyclosome repeat APH PF01636.18 KKK22821.1 - 2.8e-06 27.2 0.0 0.0094 15.7 0.0 2.8 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 KKK22821.1 - 1.5e-05 24.1 0.1 0.00029 19.9 0.0 2.3 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Cupin_8 PF13621.1 KKK22822.1 - 2.2e-39 135.4 0.0 4.6e-39 134.4 0.0 1.5 1 0 0 1 1 1 1 Cupin-like domain LCM PF04072.9 KKK22822.1 - 5.2e-18 65.2 0.0 8.7e-18 64.5 0.0 1.3 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Kelch_4 PF13418.1 KKK22822.1 - 7.1e-16 57.7 16.3 4.3e-05 23.2 0.4 6.3 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_3 PF13415.1 KKK22822.1 - 1.6e-08 34.4 6.9 0.00092 19.3 0.1 4.9 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_5 PF13854.1 KKK22822.1 - 1.8e-08 34.1 0.1 0.0002 21.1 0.0 3.8 3 0 0 3 3 3 2 Kelch motif Cupin_4 PF08007.7 KKK22822.1 - 0.00016 21.0 0.0 0.00037 19.8 0.0 1.5 1 0 0 1 1 1 1 Cupin superfamily protein Kelch_6 PF13964.1 KKK22822.1 - 0.97 9.7 3.7 13 6.1 0.0 4.2 4 0 0 4 4 4 0 Kelch motif DNA_mis_repair PF01119.14 KKK22824.1 - 6.4e-32 109.5 0.2 1.1e-31 108.7 0.1 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 KKK22824.1 - 1.6e-14 53.7 0.0 4.6e-14 52.2 0.0 1.7 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 KKK22824.1 - 1.8e-12 46.9 0.0 1.2e-10 41.0 0.0 2.8 2 1 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PNRC PF15365.1 KKK22824.1 - 0.0017 18.3 0.5 0.0051 16.7 0.3 1.8 1 0 0 1 1 1 1 Proline-rich nuclear receptor coactivator PPR_3 PF13812.1 KKK22825.1 - 0.01 16.0 0.2 0.31 11.4 0.0 3.4 4 0 0 4 4 4 0 Pentatricopeptide repeat domain TPR_14 PF13428.1 KKK22825.1 - 0.12 13.1 5.5 4.4 8.2 0.0 3.9 2 1 1 3 3 3 0 Tetratricopeptide repeat FliD_N PF02465.13 KKK22825.1 - 0.24 11.7 5.8 0.3 11.4 2.9 2.0 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus EF-hand_6 PF13405.1 KKK22826.1 - 1.2e-08 34.1 0.5 0.0039 16.9 0.0 3.0 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.27 KKK22826.1 - 0.00087 18.4 0.1 0.0034 16.5 0.0 2.1 2 0 0 2 2 2 1 EF hand EF-hand_5 PF13202.1 KKK22826.1 - 0.023 14.0 0.1 0.063 12.6 0.0 1.8 2 0 0 2 2 2 0 EF hand EF-hand_7 PF13499.1 KKK22826.1 - 0.062 13.4 5.2 0.13 12.3 0.1 2.8 1 1 1 2 2 2 0 EF-hand domain pair Aldo_ket_red PF00248.16 KKK22853.1 - 1.9e-48 164.6 0.0 2.4e-48 164.3 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family UPF0061 PF02696.9 KKK22854.1 - 1.2e-117 393.2 0.0 1.4e-117 392.9 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family TOBE PF03459.12 KKK22854.1 - 0.13 12.3 0.0 0.32 11.1 0.0 1.6 1 0 0 1 1 1 0 TOBE domain RNase_HII PF01351.13 KKK22856.1 - 3e-46 157.5 0.0 3.7e-46 157.2 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease HII DUF3280 PF11684.3 KKK22856.1 - 0.015 15.4 0.0 0.028 14.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2380) Ribosomal_L31e PF01198.14 KKK22856.1 - 0.15 11.7 0.1 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L31e F-box-like PF12937.2 KKK22857.1 - 6.8e-09 35.3 0.3 1.5e-08 34.2 0.2 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KKK22857.1 - 9e-09 34.7 1.3 1.9e-08 33.7 0.9 1.6 1 0 0 1 1 1 1 F-box domain WD40 PF00400.27 KKK22857.1 - 5.9e-06 25.9 0.7 0.25 11.3 0.0 3.4 2 0 0 2 2 2 2 WD domain, G-beta repeat zf-CCHC PF00098.18 KKK22858.1 - 3e-50 165.8 64.0 4.4e-09 35.8 1.0 7.5 8 0 0 8 8 8 7 Zinc knuckle zf-CCHC_4 PF14392.1 KKK22858.1 - 1.5e-14 53.3 43.5 0.014 15.0 0.6 7.1 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_3 PF13917.1 KKK22858.1 - 4.2e-05 23.1 47.2 0.018 14.7 0.4 6.6 3 2 3 6 6 6 4 Zinc knuckle zf-CCHC_6 PF15288.1 KKK22858.1 - 0.00027 20.5 56.8 0.017 14.8 1.3 7.6 6 2 2 8 8 8 5 Zinc knuckle SelR PF01641.13 KKK22858.1 - 2.9 7.6 7.1 0.53 9.9 1.1 2.3 2 1 0 2 2 2 0 SelR domain zf-CCHC_2 PF13696.1 KKK22858.1 - 8.8 5.9 41.8 0.7 9.4 0.1 7.0 3 2 4 7 7 7 0 Zinc knuckle Pex16 PF08610.5 KKK22859.1 - 2e-113 378.8 0.0 2.3e-113 378.6 0.0 1.0 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) SAE2 PF08573.5 KKK22860.1 - 5.7e-32 110.2 3.3 7.5e-32 109.9 0.1 2.8 2 0 0 2 2 2 1 DNA repair protein endonuclease SAE2/CtIP C-terminus DUF4200 PF13863.1 KKK22860.1 - 0.0058 16.5 7.3 0.0058 16.5 5.1 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF4200) A_deaminase PF00962.17 KKK22878.1 - 7.1e-114 380.1 0.0 9.6e-114 379.7 0.0 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase TOH_N PF12549.3 KKK22879.1 - 0.057 13.0 0.0 0.22 11.1 0.0 2.1 1 0 0 1 1 1 0 Tyrosine hydroxylase N terminal ELMO_CED12 PF04727.8 KKK22881.1 - 1.1e-50 171.5 0.1 1.6e-50 170.9 0.1 1.3 1 0 0 1 1 1 1 ELMO/CED-12 family DUF3361 PF11841.3 KKK22881.1 - 7.9e-07 28.9 0.0 2.2e-05 24.2 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3361) DUF4257 PF14074.1 KKK22881.1 - 0.14 11.8 0.0 9.2 6.0 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4257) Sec10 PF07393.6 KKK22883.1 - 2.1e-241 803.0 0.0 2.4e-241 802.8 0.0 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 MarR_2 PF12802.2 KKK22883.1 - 0.011 15.3 0.2 1.3 8.7 0.0 3.0 2 0 0 2 2 2 0 MarR family DUF2458 PF10454.4 KKK22883.1 - 0.1 12.4 1.3 1.5 8.6 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2458) Dynamin_M PF01031.15 KKK22884.1 - 3.3e-114 380.6 0.0 5.9e-114 379.8 0.0 1.4 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.18 KKK22884.1 - 9.8e-55 184.9 0.0 2.5e-54 183.5 0.0 1.7 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 KKK22884.1 - 1.1e-30 105.3 1.2 2.7e-30 104.0 0.8 1.7 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 KKK22884.1 - 0.0011 18.9 0.2 0.0091 15.9 0.1 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KKK22884.1 - 0.0077 16.7 0.0 0.026 15.0 0.0 2.0 1 0 0 1 1 1 1 Miro-like protein FeoB_N PF02421.13 KKK22884.1 - 0.062 12.5 0.1 3.9 6.7 0.0 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B zf-CCHC_4 PF14392.1 KKK22884.1 - 0.069 12.8 0.1 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 Zinc knuckle SH3_9 PF14604.1 KKK22885.1 - 9.3e-29 98.7 4.4 7.1e-16 57.5 0.2 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 KKK22885.1 - 3.8e-26 90.2 4.6 1.4e-14 53.1 0.4 2.5 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.12 KKK22885.1 - 9.4e-17 60.2 0.2 3.3e-07 29.7 0.0 2.9 3 0 0 3 3 3 2 Variant SH3 domain Cofilin_ADF PF00241.15 KKK22885.1 - 1.5e-09 37.7 0.0 3.2e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Rad17 PF03215.10 KKK22886.1 - 2e-57 195.0 0.0 3e-57 194.4 0.0 1.2 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_16 PF13191.1 KKK22886.1 - 0.00022 21.2 0.2 0.0016 18.4 0.0 2.3 2 1 1 3 3 3 1 AAA ATPase domain AAA PF00004.24 KKK22886.1 - 0.013 15.6 0.0 0.033 14.4 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 KKK22886.1 - 0.015 14.9 0.0 0.033 13.9 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain ABC_tran PF00005.22 KKK22886.1 - 0.037 14.3 0.0 0.1 12.8 0.0 1.8 1 0 0 1 1 1 0 ABC transporter T2SE PF00437.15 KKK22886.1 - 0.043 12.7 0.0 0.077 11.8 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein RNA_helicase PF00910.17 KKK22886.1 - 0.047 13.8 0.0 0.37 10.9 0.0 2.3 2 0 0 2 2 2 0 RNA helicase AAA_17 PF13207.1 KKK22886.1 - 0.073 13.8 0.0 0.16 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 KKK22886.1 - 0.088 12.9 0.0 0.24 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 KKK22886.1 - 0.091 11.9 0.0 0.17 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Zeta_toxin PF06414.7 KKK22886.1 - 0.13 11.3 0.0 0.26 10.3 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_30 PF13604.1 KKK22886.1 - 0.17 11.4 0.0 0.42 10.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain UAA PF08449.6 KKK22887.1 - 7.8e-76 254.8 19.7 2.5e-74 249.9 13.7 2.0 1 1 0 1 1 1 1 UAA transporter family TPT PF03151.11 KKK22887.1 - 4.5e-05 23.1 13.9 4.5e-05 23.1 9.6 3.1 2 2 0 2 2 2 1 Triose-phosphate Transporter family Nuc_sug_transp PF04142.10 KKK22887.1 - 0.00019 20.6 0.8 0.00019 20.6 0.5 1.9 2 0 0 2 2 2 1 Nucleotide-sugar transporter EmrE PF13536.1 KKK22887.1 - 0.002 18.2 5.5 0.002 18.2 3.8 3.4 3 2 1 4 4 4 2 Multidrug resistance efflux transporter BNR PF02012.15 KKK22888.1 - 2.1e-08 32.7 35.0 1.3 9.1 0.0 12.0 12 0 0 12 12 12 5 BNR/Asp-box repeat PSII_BNR PF14870.1 KKK22888.1 - 2.6e-06 26.6 4.5 0.019 13.9 0.0 6.2 5 2 1 6 6 6 2 Photosynthesis system II assembly factor YCF48 Mo-co_dimer PF03404.11 KKK22888.1 - 0.091 12.3 9.7 0.28 10.7 0.0 5.5 8 0 0 8 8 8 0 Mo-co oxidoreductase dimerisation domain Pkinase PF00069.20 KKK22921.1 - 5.8e-56 189.5 0.0 8e-56 189.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK22921.1 - 5e-41 140.4 0.0 7.9e-41 139.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KKK22921.1 - 1.1e-05 24.5 0.0 1.7e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KKK22921.1 - 0.00094 18.9 0.1 0.0029 17.3 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 KKK22921.1 - 0.0089 15.1 0.3 0.025 13.6 0.0 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Glyco_hydro_43 PF04616.9 KKK22923.1 - 7.6e-34 117.0 0.0 1.2e-33 116.4 0.0 1.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 Tim17 PF02466.14 KKK22924.1 - 3.9e-26 91.5 5.4 5e-26 91.2 3.7 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Pkinase PF00069.20 KKK22925.1 - 1.5e-48 165.2 0.0 2.4e-48 164.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK22925.1 - 1.7e-25 89.5 0.0 2.8e-25 88.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KKK22925.1 - 0.058 12.3 0.0 0.2 10.6 0.0 1.9 1 1 0 1 1 1 0 Kinase-like PX PF00787.19 KKK22926.1 - 1.7e-19 69.6 0.0 3.7e-18 65.3 0.0 2.8 2 1 0 2 2 2 1 PX domain Vps5 PF09325.5 KKK22926.1 - 4.8e-10 39.1 9.8 9e-06 25.1 1.5 2.1 2 0 0 2 2 2 2 Vps5 C terminal like Peptidase_C10 PF01640.12 KKK22926.1 - 0.0082 15.9 0.1 0.015 15.0 0.1 1.4 1 0 0 1 1 1 1 Peptidase C10 family DUF2428 PF10350.4 KKK22927.1 - 8.2e-80 267.4 0.0 1.8e-79 266.3 0.0 1.6 1 0 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) HEAT_2 PF13646.1 KKK22927.1 - 2.1e-05 24.6 2.7 0.57 10.5 0.1 4.3 4 0 0 4 4 4 2 HEAT repeats HEAT PF02985.17 KKK22927.1 - 4.8e-05 23.0 9.0 2.6 8.3 0.1 6.2 6 0 0 6 6 6 2 HEAT repeat HEAT_EZ PF13513.1 KKK22927.1 - 0.49 10.9 10.1 1 9.9 0.1 4.8 4 0 0 4 4 4 0 HEAT-like repeat ADH_zinc_N PF00107.21 KKK22940.1 - 7.4e-19 67.5 0.2 1.2e-18 66.8 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KKK22940.1 - 6.9e-07 30.2 0.1 1.9e-06 28.7 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KKK22940.1 - 1e-06 28.4 0.0 2e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain NAD_binding_10 PF13460.1 KKK22940.1 - 0.13 12.2 0.1 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 NADH(P)-binding TPP_enzyme_N PF02776.13 KKK22942.1 - 3e-23 82.1 0.0 7.6e-23 80.8 0.0 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 KKK22942.1 - 5.7e-15 55.2 0.0 2e-14 53.4 0.0 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 KKK22942.1 - 8.5e-14 51.3 0.0 2e-13 50.1 0.0 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Glycos_transf_1 PF00534.15 KKK22942.1 - 1.1e-13 50.9 0.0 2.1e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 DUF3492 PF11997.3 KKK22942.1 - 0.00016 21.3 0.0 0.00041 19.9 0.0 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF3492) Glyco_trans_1_4 PF13692.1 KKK22942.1 - 0.00045 20.3 0.1 0.0044 17.1 0.0 2.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 SynMuv_product PF06047.6 KKK22942.1 - 0.41 10.4 0.0 0.9 9.3 0.0 1.5 1 0 0 1 1 1 0 Ras-induced vulval development antagonist Spherulin4 PF12138.3 KKK22943.1 - 2.1e-66 223.9 1.7 2.4e-66 223.7 1.2 1.0 1 0 0 1 1 1 1 Spherulation-specific family 4 Synaptobrevin PF00957.16 KKK22943.1 - 0.026 14.1 0.3 1.2 8.7 0.4 2.2 2 0 0 2 2 2 0 Synaptobrevin DUF1510 PF07423.6 KKK22943.1 - 0.1 11.9 0.3 7.2 5.9 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) Spherulin4 PF12138.3 KKK22944.1 - 1.1e-62 211.7 0.0 1.2e-62 211.5 0.0 1.0 1 0 0 1 1 1 1 Spherulation-specific family 4 Epimerase PF01370.16 KKK22945.1 - 2.5e-35 122.0 0.0 5.8e-35 120.8 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Epimerase_Csub PF13950.1 KKK22945.1 - 8.4e-17 60.8 0.0 1.7e-16 59.8 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit 3Beta_HSD PF01073.14 KKK22945.1 - 4.7e-08 32.0 0.1 1.7e-06 26.9 0.1 2.7 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 KKK22945.1 - 2.5e-07 29.9 0.0 6.6e-07 28.5 0.0 1.6 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.10 KKK22945.1 - 4.9e-06 25.6 0.0 0.00016 20.6 0.0 2.9 3 1 0 3 3 3 1 Polysaccharide biosynthesis protein adh_short PF00106.20 KKK22945.1 - 0.00021 21.2 0.0 0.00043 20.2 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KKK22945.1 - 0.00034 20.3 0.0 0.0007 19.3 0.0 1.5 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KKK22945.1 - 0.014 15.4 0.1 0.8 9.6 0.0 2.8 3 0 0 3 3 3 0 NADH(P)-binding UDPG_MGDP_dh_N PF03721.9 KKK22945.1 - 0.034 13.5 0.0 0.06 12.7 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Sugar_tr PF00083.19 KKK22946.1 - 4e-52 177.3 3.0 4.5e-52 177.1 2.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KKK22946.1 - 4.3e-08 32.2 31.4 2.1e-05 23.3 6.6 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily FTO_CTD PF12934.2 KKK22946.1 - 0.075 12.6 0.1 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 FTO C-terminal domain Gate PF07670.9 KKK22946.1 - 0.13 12.1 8.8 0.026 14.4 3.4 1.7 2 0 0 2 2 2 0 Nucleoside recognition DUF427 PF04248.7 KKK22947.1 - 1.6e-29 101.4 0.3 1.7e-29 101.2 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF427) MFS_1 PF07690.11 KKK22948.1 - 1.1e-32 113.1 23.9 1.1e-32 113.1 16.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KKK22950.1 - 4.9e-79 266.0 29.0 5.7e-79 265.7 20.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KKK22950.1 - 5.8e-17 61.4 25.4 5.8e-17 61.4 17.6 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.1 KKK22950.1 - 1.4e-07 30.3 33.1 5.4e-05 21.7 0.9 4.1 3 1 1 4 4 4 4 MFS/sugar transport protein 7TM_GPCR_Sra PF02117.11 KKK22950.1 - 0.012 14.2 1.2 0.026 13.1 0.1 2.0 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Sra NfeD PF01957.13 KKK22950.1 - 9.4 6.3 14.7 2.1 8.4 1.8 3.7 3 1 0 3 3 3 0 NfeD-like C-terminal, partner-binding APH PF01636.18 KKK22967.1 - 3.6e-13 49.7 0.0 5.8e-13 49.1 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KKK22967.1 - 0.00012 21.7 0.0 0.00024 20.7 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.17 KKK22967.1 - 0.0026 17.1 0.0 0.019 14.3 0.0 2.0 2 0 0 2 2 2 1 RIO1 family ADH_N PF08240.7 KKK22968.1 - 2.9e-28 97.8 0.1 5.7e-28 96.8 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KKK22968.1 - 2.5e-25 88.4 0.8 4.8e-25 87.5 0.6 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KKK22968.1 - 0.00073 20.4 0.1 0.0013 19.6 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 KKK22968.1 - 0.0067 16.0 0.6 0.011 15.3 0.4 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.14 KKK22968.1 - 0.0071 15.5 0.2 0.013 14.6 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain SNF2_N PF00176.18 KKK22969.1 - 3.1e-70 236.3 4.1 3.1e-70 236.3 2.9 1.8 2 0 0 2 2 2 1 SNF2 family N-terminal domain DBINO PF13892.1 KKK22969.1 - 4.3e-52 175.8 20.2 4.3e-52 175.8 14.0 4.5 3 1 1 4 4 4 1 DNA-binding domain Helicase_C PF00271.26 KKK22969.1 - 1.2e-16 60.3 0.0 3.5e-16 58.8 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Aminotran_1_2 PF00155.16 KKK22970.1 - 7.6e-68 229.0 0.0 1.4e-48 165.6 0.0 2.2 1 1 1 2 2 2 2 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 KKK22970.1 - 1.6e-05 23.4 0.0 2.6e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 KKK22970.1 - 1.8e-05 23.6 0.0 3.3e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 KKK22970.1 - 0.00031 19.9 0.2 0.0007 18.7 0.2 1.5 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.16 KKK22970.1 - 0.033 13.3 0.0 0.075 12.1 0.0 1.5 1 0 0 1 1 1 0 Beta-eliminating lyase RNA_pol_I_A49 PF06870.7 KKK22971.1 - 3.8e-52 177.1 2.3 2.3e-38 131.7 1.7 2.8 2 1 0 2 2 2 2 A49-like RNA polymerase I associated factor NST1 PF13945.1 KKK22980.1 - 1.1e-71 240.8 0.9 1.1e-71 240.8 0.6 4.4 2 2 2 4 4 4 1 Salt tolerance down-regulator Ras PF00071.17 KKK22981.1 - 9.8e-36 122.5 0.0 1.1e-35 122.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KKK22981.1 - 4.7e-09 36.7 0.0 1.2e-08 35.4 0.0 1.6 2 0 0 2 2 2 1 Miro-like protein DUF4055 PF13264.1 KKK22981.1 - 0.16 12.0 0.0 0.21 11.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4055) Fungal_trans PF04082.13 KKK23012.1 - 2.7e-08 33.0 3.7 3.5e-08 32.6 1.6 1.7 1 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK23012.1 - 0.021 14.7 0.7 0.046 13.6 0.5 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Transket_pyr PF02779.19 KKK23016.1 - 1.8e-64 216.4 0.0 3.4e-64 215.5 0.0 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 KKK23016.1 - 1.3e-56 191.5 0.0 1.8e-56 191.0 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component Aldo_ket_red PF00248.16 KKK23017.1 - 2.9e-56 190.3 0.0 3.4e-56 190.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Hydrolase_6 PF13344.1 KKK23018.1 - 1.1e-23 83.0 0.0 2.1e-23 82.1 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KKK23018.1 - 8.1e-18 63.9 0.0 2.1e-17 62.5 0.0 1.7 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 KKK23018.1 - 0.0074 16.7 0.0 0.12 12.7 0.0 2.4 2 1 1 3 3 3 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 KKK23018.1 - 0.011 15.9 0.0 0.91 9.7 0.0 2.6 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase GATase PF00117.23 KKK23019.1 - 4.4e-38 130.6 0.0 7.4e-38 129.9 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GMP_synt_C PF00958.17 KKK23019.1 - 5.1e-34 115.8 0.0 1e-33 114.8 0.0 1.6 1 0 0 1 1 1 1 GMP synthase C terminal domain NAD_synthase PF02540.12 KKK23019.1 - 3.9e-10 39.0 0.0 1.4e-06 27.4 0.0 2.3 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.8 KKK23019.1 - 3.8e-06 26.4 0.1 1.2e-05 24.9 0.0 1.8 1 1 0 1 1 1 1 Peptidase C26 tRNA_Me_trans PF03054.11 KKK23019.1 - 0.0003 19.4 0.1 0.00089 17.9 0.0 1.7 2 0 0 2 2 2 1 tRNA methyl transferase ThiI PF02568.9 KKK23019.1 - 0.0032 16.9 0.0 0.007 15.8 0.0 1.5 1 0 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) PAPS_reduct PF01507.14 KKK23019.1 - 0.0065 16.3 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family QueC PF06508.8 KKK23019.1 - 0.0098 15.1 0.0 0.23 10.7 0.0 2.2 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC Arginosuc_synth PF00764.14 KKK23019.1 - 0.045 12.8 0.1 0.067 12.2 0.1 1.2 1 0 0 1 1 1 0 Arginosuccinate synthase Asn_synthase PF00733.16 KKK23019.1 - 0.048 13.1 0.0 0.093 12.2 0.0 1.4 1 0 0 1 1 1 0 Asparagine synthase LRR_4 PF12799.2 KKK23020.1 - 0.00011 21.7 9.2 0.031 13.8 0.2 4.7 4 2 1 5 5 5 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KKK23020.1 - 0.00031 20.3 0.6 13 6.2 0.0 5.5 4 1 0 4 4 4 1 Leucine Rich Repeat LRR_6 PF13516.1 KKK23020.1 - 0.0013 18.5 5.1 1.4 9.1 0.0 5.2 5 0 0 5 5 5 1 Leucine Rich repeat F-box-like PF12937.2 KKK23020.1 - 0.0024 17.5 0.0 0.0055 16.4 0.0 1.7 1 0 0 1 1 1 1 F-box-like LRR_8 PF13855.1 KKK23020.1 - 0.0084 15.8 5.1 3.3 7.5 0.1 3.7 3 0 0 3 3 3 2 Leucine rich repeat LURAP PF14854.1 KKK23020.1 - 0.033 13.8 0.5 0.073 12.7 0.3 1.5 1 0 0 1 1 1 0 Leucine rich adaptor protein F-box PF00646.28 KKK23020.1 - 0.036 13.7 1.4 0.27 10.9 0.7 2.7 2 1 0 2 2 2 0 F-box domain LRR_7 PF13504.1 KKK23020.1 - 0.22 11.8 4.3 1.1e+02 3.7 0.0 5.5 5 0 0 5 5 5 0 Leucine rich repeat BSD PF03909.12 KKK23021.1 - 1.4e-27 95.2 13.7 6.4e-15 54.6 0.4 3.5 4 0 0 4 4 4 2 BSD domain TFIIH_BTF_p62_N PF08567.6 KKK23021.1 - 2.5e-27 94.3 0.1 1.7e-26 91.6 0.0 2.3 2 0 0 2 2 2 1 TFIIH p62 subunit, N-terminal domain DctQ PF04290.7 KKK23022.1 - 0.79 9.4 8.7 0.22 11.3 1.9 2.2 2 0 0 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component ING PF12998.2 KKK23023.1 - 7.7e-12 45.4 0.0 1.8e-11 44.2 0.0 1.6 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 KKK23023.1 - 1.5e-09 37.3 7.4 2.4e-09 36.7 5.1 1.3 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.1 KKK23023.1 - 0.063 13.4 1.4 0.13 12.3 1.0 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain DUF4378 PF14309.1 KKK23023.1 - 0.071 13.1 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4378) Myc_N PF01056.13 KKK23024.1 - 0.077 12.1 16.7 0.027 13.6 3.5 3.0 3 0 0 3 3 3 0 Myc amino-terminal region Hus1 PF04005.7 KKK23031.1 - 1.1e-111 372.4 0.0 1.3e-111 372.2 0.0 1.0 1 0 0 1 1 1 1 Hus1-like protein DUF4552 PF15089.1 KKK23031.1 - 0.01 14.7 0.3 0.015 14.2 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4552) APS-reductase_C PF12139.3 KKK23031.1 - 0.052 13.7 0.0 0.1 12.7 0.0 1.4 1 0 0 1 1 1 0 Adenosine-5'-phosphosulfate reductase beta subunit GAS2 PF02187.12 KKK23032.1 - 0.00024 20.7 0.1 0.00047 19.8 0.1 1.4 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain DUF1777 PF08648.7 KKK23033.1 - 8.2e-23 81.0 75.9 5.7e-22 78.3 48.8 2.8 1 1 1 2 2 2 1 Protein of unknown function (DUF1777) Sec16_C PF12931.2 KKK23034.1 - 4.4e-102 341.6 0.0 6e-102 341.2 0.0 1.2 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16_N PF12935.2 KKK23034.1 - 3.4e-64 217.1 22.2 3.4e-64 217.1 15.4 3.5 3 0 0 3 3 3 1 Vesicle coat trafficking protein Sec16 N-terminus Sec16 PF12932.2 KKK23034.1 - 7.3e-33 113.0 0.0 1.5e-32 112.0 0.0 1.6 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region TPR_16 PF13432.1 KKK23034.1 - 0.016 15.8 10.8 1.7 9.3 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat MMtag PF10159.4 KKK23035.1 - 4.5e-34 116.3 4.9 6.7e-34 115.7 3.4 1.3 1 0 0 1 1 1 1 Kinase phosphorylation protein Glyco_hydro_63 PF03200.11 KKK23036.1 - 1.4e-240 800.4 0.0 7.7e-240 797.9 0.0 1.8 1 1 0 1 1 1 1 Mannosyl oligosaccharide glucosidase DAO PF01266.19 KKK23036.1 - 5.8e-58 196.5 0.6 1e-57 195.7 0.4 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KKK23036.1 - 4.8e-06 26.5 0.2 1.3e-05 25.0 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 KKK23036.1 - 0.004 15.8 0.1 0.03 12.9 0.1 2.0 2 0 0 2 2 2 1 Tryptophan halogenase Pyr_redox_2 PF07992.9 KKK23036.1 - 0.0054 16.6 0.6 1.1 9.0 0.0 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Trehalase PF01204.13 KKK23036.1 - 0.0077 14.9 0.3 0.015 14.0 0.2 1.4 1 0 0 1 1 1 1 Trehalase FAD_binding_2 PF00890.19 KKK23036.1 - 0.022 13.6 0.2 0.33 9.7 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain Pyr_redox PF00070.22 KKK23036.1 - 0.034 14.5 0.8 0.083 13.3 0.0 2.0 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Bac_rhamnosid PF05592.6 KKK23036.1 - 0.06 11.5 0.0 0.1 10.8 0.0 1.2 1 0 0 1 1 1 0 Bacterial alpha-L-rhamnosidase CRT10 PF08728.5 KKK23037.1 - 2.2e-24 85.4 0.0 2e-15 55.8 0.0 2.3 2 0 0 2 2 2 2 CRT10 SR-25 PF10500.4 KKK23037.1 - 1.1 8.6 10.9 2 7.8 7.6 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Pex14_N PF04695.8 KKK23037.1 - 1.5 8.8 6.4 2.5 8.1 3.4 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Hist_deacetyl PF00850.14 KKK23042.1 - 3e-95 319.0 0.1 5.8e-95 318.1 0.0 1.4 1 0 0 1 1 1 1 Histone deacetylase domain Arb2 PF09757.4 KKK23042.1 - 1.2e-55 187.6 0.1 5.1e-55 185.6 0.0 1.9 2 0 0 2 2 2 1 Arb2 domain Bys1 PF04681.7 KKK23043.1 - 2.6e-11 43.4 0.4 3.1e-11 43.2 0.3 1.0 1 0 0 1 1 1 1 Blastomyces yeast-phase-specific protein NUDIX_2 PF13869.1 KKK23044.1 - 1.6e-82 275.4 0.0 1.9e-82 275.2 0.0 1.1 1 0 0 1 1 1 1 Nucleotide hydrolase Peptidase_M16_C PF05193.16 KKK23045.1 - 5.6e-32 110.8 0.0 9e-23 80.8 0.0 3.3 3 1 0 4 4 4 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 KKK23045.1 - 1.3e-31 109.3 4.1 1.4e-22 80.1 0.3 3.6 3 1 1 4 4 4 2 Insulinase (Peptidase family M16) ketoacyl-synt PF00109.21 KKK23049.1 - 3.3e-18 66.1 0.0 7.4e-18 64.9 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain adh_short_C2 PF13561.1 KKK23049.1 - 2.8e-16 60.0 0.0 5.1e-16 59.1 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Ketoacyl-synt_C PF02801.17 KKK23049.1 - 4.6e-16 58.7 0.0 1e-15 57.6 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ACPS PF01648.15 KKK23049.1 - 8.7e-14 51.3 0.0 1.8e-13 50.2 0.0 1.6 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily adh_short PF00106.20 KKK23049.1 - 3.6e-06 26.9 0.0 6.5e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase Thiolase_N PF00108.18 KKK23049.1 - 0.11 11.4 1.8 0.75 8.7 0.0 2.3 2 0 0 2 2 2 0 Thiolase, N-terminal domain DUF3881 PF12997.2 KKK23049.1 - 0.32 9.9 0.0 0.58 9.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function, E. rectale Gene description (DUF3881) Acyl_transf_1 PF00698.16 KKK23050.1 - 8.2e-50 169.9 0.0 4.3e-48 164.2 0.0 2.8 2 1 0 2 2 2 1 Acyl transferase domain DUF1729 PF08354.5 KKK23050.1 - 1.3e-28 98.4 0.1 3.2e-28 97.2 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) MaoC_dehydratas PF01575.14 KKK23050.1 - 3.8e-24 84.4 0.0 8.6e-24 83.2 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.1 KKK23050.1 - 6.5e-07 29.1 0.0 1.5e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase NMO PF03060.10 KKK23050.1 - 0.011 14.9 0.3 0.042 12.9 0.2 1.9 1 1 0 1 1 1 0 Nitronate monooxygenase FAD_binding_3 PF01494.14 KKK23051.1 - 6.2e-13 48.5 7.1 8.1e-08 31.7 0.1 3.0 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.19 KKK23051.1 - 0.0011 17.9 2.6 0.0015 17.4 1.2 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KKK23051.1 - 0.0019 18.1 0.4 0.0052 16.7 0.3 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.13 KKK23051.1 - 0.017 14.7 0.1 0.03 13.9 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.22 KKK23051.1 - 0.029 14.7 1.8 0.085 13.2 0.2 2.5 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KKK23051.1 - 0.044 13.5 0.0 0.31 10.7 0.1 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding TrkA_N PF02254.13 KKK23051.1 - 0.083 12.8 0.1 0.16 11.9 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_2 PF03446.10 KKK23051.1 - 0.095 12.5 0.0 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 KKK23051.1 - 0.12 12.7 0.5 0.33 11.4 0.3 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent MFS_1 PF07690.11 KKK23052.1 - 1.4e-39 135.8 68.1 7.1e-35 120.3 31.2 3.3 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KKK23052.1 - 4.2e-23 81.4 25.2 5.6e-23 80.9 17.5 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 KKK23052.1 - 4.1e-17 61.9 9.8 4.1e-17 61.9 6.8 2.4 2 0 0 2 2 2 2 Sugar (and other) transporter DUF3522 PF12036.3 KKK23052.1 - 0.25 11.0 6.8 24 4.6 2.3 3.9 2 1 1 3 3 3 0 Protein of unknown function (DUF3522) Transferase PF02458.10 KKK23053.1 - 4.2e-10 38.6 0.0 8.1e-08 31.1 0.0 2.1 2 0 0 2 2 2 2 Transferase family AraC_binding PF02311.14 KKK23053.1 - 0.028 14.0 0.0 0.051 13.2 0.0 1.4 1 0 0 1 1 1 0 AraC-like ligand binding domain Fungal_trans PF04082.13 KKK23054.1 - 2.8e-17 62.4 0.7 3.9e-17 61.9 0.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK23054.1 - 1.5e-09 37.5 10.1 3.1e-09 36.5 7.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Clusterin PF01093.12 KKK23054.1 - 0.78 8.4 2.6 1.7 7.3 1.8 1.5 1 0 0 1 1 1 0 Clusterin ketoacyl-synt PF00109.21 KKK23055.1 - 1.5e-57 195.0 0.2 5.5e-56 189.8 0.2 2.4 1 1 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 KKK23055.1 - 9.7e-34 117.1 0.0 2.4e-33 115.8 0.0 1.6 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 KKK23055.1 - 2.8e-29 101.3 0.0 1.1e-28 99.4 0.0 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain NAD_binding_4 PF07993.7 KKK23055.1 - 2e-27 95.7 0.0 3.3e-27 94.9 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.20 KKK23055.1 - 2.1e-15 56.7 0.3 5.5e-15 55.3 0.2 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_12 PF08242.7 KKK23055.1 - 2.1e-13 50.5 0.0 8.8e-13 48.5 0.0 2.2 2 0 0 2 2 1 1 Methyltransferase domain Epimerase PF01370.16 KKK23055.1 - 1.8e-07 30.8 0.0 3.8e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Methyltransf_31 PF13847.1 KKK23055.1 - 4.3e-07 29.6 0.0 9e-07 28.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KKK23055.1 - 3.7e-05 24.1 0.0 0.00015 22.2 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KKK23055.1 - 9.4e-05 22.1 0.0 0.00033 20.4 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KKK23055.1 - 0.00011 22.4 0.0 0.00034 20.9 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.20 KKK23055.1 - 0.00025 21.0 0.3 0.00099 19.0 0.2 2.1 1 1 0 1 1 1 1 short chain dehydrogenase Methyltransf_18 PF12847.2 KKK23055.1 - 0.0014 19.1 0.0 0.0057 17.2 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.18 KKK23055.1 - 0.014 14.4 0.1 0.036 13.0 0.1 1.6 1 0 0 1 1 1 0 Thiolase, N-terminal domain Ubie_methyltran PF01209.13 KKK23055.1 - 0.018 14.2 0.0 0.033 13.2 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family 3Beta_HSD PF01073.14 KKK23055.1 - 0.11 11.2 0.3 6 5.4 0.0 2.4 3 0 0 3 3 3 0 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 KKK23055.1 - 0.38 9.6 0.0 0.71 8.7 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Cellulase PF00150.13 KKK23056.1 - 2.1e-19 69.7 0.4 2.8e-19 69.4 0.3 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_42 PF02449.10 KKK23056.1 - 0.0012 18.0 0.1 0.012 14.7 0.1 2.0 2 0 0 2 2 2 1 Beta-galactosidase Glyco_hydro_2_C PF02836.12 KKK23056.1 - 0.0045 15.9 0.1 0.015 14.2 0.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain S-methyl_trans PF02574.11 KKK23057.1 - 7.6e-26 91.1 0.0 1.6e-24 86.7 0.0 2.5 1 1 0 1 1 1 1 Homocysteine S-methyltransferase Tail_tube PF10618.4 KKK23057.1 - 0.1 12.3 0.0 0.26 11.0 0.0 1.6 2 0 0 2 2 2 0 Phage tail tube protein SRR1 PF07985.7 KKK23058.1 - 0.0076 16.1 0.0 0.014 15.3 0.0 1.5 1 0 0 1 1 1 1 SRR1 Peptidase_A4 PF01828.12 KKK23059.1 - 6.7e-86 286.6 9.2 8.1e-86 286.3 6.4 1.1 1 0 0 1 1 1 1 Peptidase A4 family Sugar_tr PF00083.19 KKK23060.1 - 7.5e-138 459.8 24.6 8.5e-138 459.6 17.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KKK23060.1 - 1.2e-20 73.5 46.8 2.7e-18 65.7 16.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.13 KKK23069.1 - 5.1e-10 38.6 0.1 9e-10 37.8 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK23069.1 - 7.3e-07 28.9 10.8 2e-06 27.6 7.5 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_43 PF04616.9 KKK23070.1 - 2.4e-28 99.0 0.5 3.2e-28 98.6 0.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Drc1-Sld2 PF11719.3 KKK23071.1 - 9.4e-136 453.2 20.8 1.1e-135 453.0 14.4 1.0 1 0 0 1 1 1 1 DNA replication and checkpoint protein Suc_Fer-like PF06999.7 KKK23072.1 - 6.3e-47 160.5 0.0 8e-47 160.1 0.0 1.0 1 0 0 1 1 1 1 Sucrase/ferredoxin-like Opiods_neuropep PF01160.13 KKK23072.1 - 0.098 12.4 1.0 0.19 11.5 0.7 1.4 1 0 0 1 1 1 0 Vertebrate endogenous opioids neuropeptide DUF2410 PF10307.4 KKK23073.1 - 9.6e-86 286.2 0.0 1.3e-85 285.8 0.0 1.2 1 0 0 1 1 1 1 Hypothetical protein (DUF2410) zf-RING_2 PF13639.1 KKK23074.1 - 3.4e-09 36.3 4.1 5.8e-09 35.6 2.9 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 KKK23074.1 - 9.3e-08 31.9 4.1 1.5e-07 31.3 2.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KKK23074.1 - 1.6e-07 30.8 1.8 2.4e-07 30.3 1.2 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KKK23074.1 - 2.7e-07 30.1 2.7 4.2e-07 29.4 1.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KKK23074.1 - 9.2e-06 25.6 4.1 2.5e-05 24.2 2.8 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 KKK23074.1 - 0.074 12.7 1.8 0.13 12.0 1.3 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-MIZ PF02891.15 KKK23074.1 - 0.11 12.0 2.5 0.21 11.1 1.7 1.4 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-C3HC4_4 PF15227.1 KKK23074.1 - 0.11 12.3 4.5 0.21 11.5 3.1 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Nnf1 PF03980.9 KKK23104.1 - 1.4e-27 95.8 0.9 1.4e-27 95.8 0.6 1.8 2 0 0 2 2 2 1 Nnf1 Spc42p PF11544.3 KKK23104.1 - 0.049 13.5 1.1 0.2 11.5 0.0 2.5 2 1 1 3 3 3 0 Spindle pole body component Spc42p Caveolin PF01146.12 KKK23104.1 - 0.14 11.7 0.0 0.26 10.8 0.0 1.4 1 0 0 1 1 1 0 Caveolin TPR_11 PF13414.1 KKK23105.1 - 6.1e-06 25.8 7.9 0.043 13.4 0.1 4.8 4 1 0 4 4 4 3 TPR repeat TPR_17 PF13431.1 KKK23105.1 - 0.0061 16.6 0.4 2.3 8.6 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 KKK23105.1 - 0.16 12.6 16.6 0.53 11.0 0.2 4.5 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.1 KKK23105.1 - 0.4 10.6 9.6 1.5 8.8 0.1 4.2 3 1 1 4 4 4 0 Tetratricopeptide repeat AAA PF00004.24 KKK23107.1 - 2.7e-48 163.4 0.0 3.8e-43 146.8 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 KKK23107.1 - 6.4e-05 22.4 0.0 0.00024 20.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KKK23107.1 - 7.6e-05 23.5 0.0 0.0014 19.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 KKK23107.1 - 7.6e-05 21.8 0.0 0.00043 19.4 0.0 2.2 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus Parvo_NS1 PF01057.12 KKK23107.1 - 0.00048 19.0 0.0 0.00081 18.3 0.0 1.2 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA_16 PF13191.1 KKK23107.1 - 0.00054 19.9 0.3 0.025 14.5 0.0 3.2 2 1 1 3 3 2 1 AAA ATPase domain AAA_22 PF13401.1 KKK23107.1 - 0.00083 19.5 0.0 0.0067 16.5 0.0 2.5 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 KKK23107.1 - 0.0015 17.9 0.0 0.0029 17.0 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein RNA_helicase PF00910.17 KKK23107.1 - 0.0022 18.1 0.0 0.013 15.7 0.0 2.3 3 0 0 3 3 2 1 RNA helicase AAA_2 PF07724.9 KKK23107.1 - 0.0031 17.4 0.0 0.0079 16.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) TIP49 PF06068.8 KKK23107.1 - 0.0059 15.3 0.0 0.0093 14.7 0.0 1.2 1 0 0 1 1 1 1 TIP49 C-terminus AAA_19 PF13245.1 KKK23107.1 - 0.0085 15.8 1.4 0.028 14.1 0.0 2.6 3 0 0 3 3 2 1 Part of AAA domain Mg_chelatase PF01078.16 KKK23107.1 - 0.023 13.8 0.1 0.045 12.8 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 KKK23107.1 - 0.024 14.3 0.0 0.076 12.7 0.0 1.9 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) KaiC PF06745.8 KKK23107.1 - 0.034 13.2 0.0 0.07 12.2 0.0 1.4 1 0 0 1 1 1 0 KaiC PhoH PF02562.11 KKK23107.1 - 0.035 13.3 0.0 0.086 12.0 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein AAA_18 PF13238.1 KKK23107.1 - 0.037 14.3 0.0 0.097 12.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 KKK23107.1 - 0.074 13.0 0.0 0.18 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 KKK23107.1 - 0.084 12.7 0.4 0.28 11.0 0.0 2.2 2 0 0 2 2 1 0 AAA domain AAA_14 PF13173.1 KKK23107.1 - 0.13 12.1 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 KKK23107.1 - 0.14 11.7 0.1 0.23 11.0 0.1 1.3 1 0 0 1 1 1 0 AAA domain PPV_E1_C PF00519.12 KKK23107.1 - 0.19 10.2 0.0 0.3 9.6 0.0 1.1 1 0 0 1 1 1 0 Papillomavirus helicase Choline_transpo PF04515.7 KKK23108.1 - 8.3e-106 353.4 23.7 8.3e-106 353.4 16.4 2.2 2 0 0 2 2 2 1 Plasma-membrane choline transporter RabGAP-TBC PF00566.13 KKK23108.1 - 1.3e-36 126.1 0.3 2.7e-32 111.9 0.1 2.6 2 0 0 2 2 2 2 Rab-GTPase-TBC domain Fructosamin_kin PF03881.9 KKK23108.1 - 0.028 13.4 0.3 0.1 11.5 0.0 1.9 2 0 0 2 2 2 0 Fructosamine kinase DUF2370 PF10176.4 KKK23108.1 - 0.034 13.5 0.6 0.17 11.2 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2370) DUF4191 PF13829.1 KKK23108.1 - 2.7 7.0 4.9 18 4.3 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) DUF4243 PF14027.1 KKK23109.1 - 9.1e-87 291.5 4.4 1.1e-86 291.3 3.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) AA_permease_2 PF13520.1 KKK23110.1 - 5.6e-43 147.0 60.1 6.8e-43 146.7 41.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KKK23110.1 - 2.2e-13 49.4 50.7 1.2e-12 46.9 35.1 2.4 1 1 0 1 1 1 1 Amino acid permease TauD PF02668.11 KKK23111.1 - 0.0013 18.4 0.0 0.0017 18.0 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family MFS_1 PF07690.11 KKK23112.1 - 5.3e-25 87.8 20.4 6.5e-25 87.5 14.1 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Myb_DNA-binding PF00249.26 KKK23112.1 - 0.14 12.2 0.6 2 8.5 0.1 2.6 3 0 0 3 3 3 0 Myb-like DNA-binding domain Sugar_tr PF00083.19 KKK23113.1 - 2.8e-07 29.4 0.8 3.3e-07 29.2 0.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter V-SNARE_C PF12352.3 KKK23113.1 - 0.013 15.5 0.0 0.018 15.1 0.0 1.2 1 0 0 1 1 1 0 Snare region anchored in the vesicle membrane C-terminus TauD PF02668.11 KKK23114.1 - 7.3e-21 74.9 0.1 8.6e-21 74.7 0.1 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family HECT_2 PF09814.4 KKK23115.1 - 1e-84 284.2 0.0 1.2e-84 284.0 0.0 1.0 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding DUF515 PF04415.7 KKK23137.1 - 2.8 6.0 6.2 4.7 5.3 4.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF515) PFK PF00365.15 KKK23138.1 - 9.2e-167 553.0 1.8 2.4e-120 400.7 0.2 2.1 2 0 0 2 2 2 2 Phosphofructokinase NAD_kinase PF01513.16 KKK23138.1 - 0.0051 15.6 0.1 1.1 7.9 0.0 2.3 2 0 0 2 2 2 2 ATP-NAD kinase DUF4646 PF15496.1 KKK23138.1 - 0.13 12.3 0.0 0.32 11.0 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4646) ISN1 PF06437.6 KKK23139.1 - 2e-194 645.9 0.0 2.2e-194 645.8 0.0 1.0 1 0 0 1 1 1 1 IMP-specific 5'-nucleotidase DUF2638 PF10937.3 KKK23154.1 - 1.7e-39 135.2 0.2 2e-39 135.0 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2638) DUF647 PF04884.9 KKK23155.1 - 1.6e-104 348.5 4.1 2.2e-104 348.0 2.8 1.2 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis M20_dimer PF07687.9 KKK23157.1 - 2.1e-16 59.6 0.1 4.2e-16 58.6 0.1 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.23 KKK23157.1 - 3.1e-07 30.0 9.3 1.4e-06 27.9 6.4 1.9 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Med18 PF09637.5 KKK23158.1 - 7.1e-68 228.8 0.0 8e-68 228.6 0.0 1.0 1 0 0 1 1 1 1 Med18 protein RGS PF00615.14 KKK23159.1 - 1.7e-12 47.4 0.0 2.7e-12 46.8 0.0 1.2 1 0 0 1 1 1 1 Regulator of G protein signaling domain PNK3P PF08645.6 KKK23160.1 - 4.9e-57 191.8 0.1 8.9e-57 190.9 0.0 1.5 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.1 KKK23160.1 - 8.3e-34 116.5 0.0 4.1e-33 114.2 0.0 2.1 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.5 KKK23160.1 - 8.9e-08 31.6 0.2 0.00082 18.6 0.0 2.5 2 1 1 3 3 3 2 Chromatin associated protein KTI12 Zeta_toxin PF06414.7 KKK23160.1 - 0.00049 19.2 0.0 0.27 10.3 0.0 2.4 1 1 1 2 2 2 2 Zeta toxin HAD_2 PF13419.1 KKK23160.1 - 0.0047 17.1 1.2 2.5 8.3 0.1 3.3 1 1 1 2 2 2 1 Haloacid dehalogenase-like hydrolase AAA_18 PF13238.1 KKK23160.1 - 0.025 14.8 0.1 0.39 11.0 0.1 2.6 2 1 1 3 3 3 0 AAA domain DUF4243 PF14027.1 KKK23172.1 - 1.1e-84 284.6 0.2 1.5e-84 284.3 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) NAD_binding_10 PF13460.1 KKK23172.1 - 5.1e-13 49.4 0.0 9.2e-13 48.5 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 KKK23172.1 - 0.00046 19.5 0.1 0.001 18.3 0.0 1.6 2 0 0 2 2 2 1 NmrA-like family 3Beta_HSD PF01073.14 KKK23172.1 - 0.0047 15.6 0.5 0.0068 15.1 0.0 1.5 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 KKK23172.1 - 0.022 14.1 0.0 0.059 12.7 0.0 1.7 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 KKK23172.1 - 0.074 13.3 0.0 1.4 9.2 0.0 2.8 3 0 0 3 3 3 0 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.7 KKK23172.1 - 0.094 11.6 0.0 0.19 10.6 0.0 1.5 1 0 0 1 1 1 0 Male sterility protein AMP-binding PF00501.23 KKK23173.1 - 9e-50 169.2 0.1 1.2e-49 168.8 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KKK23173.1 - 0.096 13.6 0.0 0.27 12.2 0.0 1.8 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain GST_C PF00043.20 KKK23175.1 - 1.4e-08 34.6 0.0 2.2e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KKK23175.1 - 1.8e-08 34.1 0.3 3e-08 33.4 0.2 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KKK23175.1 - 2.7e-06 27.7 0.1 4.4e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 KKK23175.1 - 9.5e-06 25.7 0.0 2e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 KKK23175.1 - 0.015 15.5 0.0 0.024 14.8 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Rieske PF00355.21 KKK23175.1 - 0.034 13.7 0.0 0.054 13.0 0.0 1.3 1 0 0 1 1 1 0 Rieske [2Fe-2S] domain PNP_UDP_1 PF01048.15 KKK23176.1 - 4e-08 32.5 1.2 1.7e-07 30.4 0.9 1.8 1 1 0 1 1 1 1 Phosphorylase superfamily TRF PF08558.5 KKK23177.1 - 5.9e-92 307.3 2.3 9.3e-92 306.6 1.6 1.3 1 0 0 1 1 1 1 Telomere repeat binding factor (TRF) TFIID_30kDa PF03540.8 KKK23177.1 - 1.1e-23 82.8 0.1 2.5e-23 81.6 0.0 1.7 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit Myb_DNA-binding PF00249.26 KKK23177.1 - 2.3e-05 24.3 0.0 4.2e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF844 PF05815.6 KKK23177.1 - 0.7 8.6 7.4 1.2 7.8 5.1 1.3 1 0 0 1 1 1 0 Baculovirus protein of unknown function (DUF844) SBF PF01758.11 KKK23178.1 - 3.2e-52 176.6 8.5 3.2e-52 176.6 5.9 2.4 3 1 0 3 3 3 1 Sodium Bile acid symporter family DUF3671 PF12420.3 KKK23178.1 - 0.022 14.7 0.1 3.2 7.7 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function DUF2061 PF09834.4 KKK23178.1 - 2.2 8.5 5.5 1.2 9.3 0.3 3.1 2 1 1 3 3 3 0 Predicted membrane protein (DUF2061) IPK PF03770.11 KKK23179.1 - 1.8e-60 203.9 0.0 2.6e-60 203.4 0.0 1.2 1 0 0 1 1 1 1 Inositol polyphosphate kinase Arb1 PF09692.5 KKK23180.1 - 1.8e-155 517.6 0.1 2.1e-155 517.4 0.1 1.0 1 0 0 1 1 1 1 Argonaute siRNA chaperone (ARC) complex subunit Arb1 DUF600 PF04634.7 KKK23180.1 - 0.0087 16.0 0.0 0.018 15.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF600 FAD_binding_3 PF01494.14 KKK23181.1 - 1.5e-09 37.3 0.1 6e-06 25.5 0.0 3.2 3 0 0 3 3 3 2 FAD binding domain DAO PF01266.19 KKK23181.1 - 7.1e-05 21.8 0.0 0.00011 21.2 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KKK23181.1 - 7.4e-05 22.5 0.1 0.0055 16.4 0.0 2.6 3 0 0 3 3 3 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 KKK23181.1 - 0.0004 20.3 0.0 0.0019 18.1 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KKK23181.1 - 0.059 13.2 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DOG1 PF14144.1 KKK23181.1 - 0.42 10.6 1.7 0.57 10.2 0.1 2.1 2 1 0 2 2 2 0 Seed dormancy control FMN_red PF03358.10 KKK23182.1 - 2.9e-22 78.8 0.0 4.2e-22 78.3 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase LMWPc PF01451.16 KKK23183.1 - 1.8e-29 102.8 0.0 2e-29 102.6 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase Toxin_1 PF00087.16 KKK23183.1 - 0.11 12.8 0.0 0.18 12.2 0.0 1.3 1 0 0 1 1 1 0 Snake toxin Ribosomal_S19 PF00203.16 KKK23184.1 - 6.1e-21 73.8 0.0 7.4e-21 73.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 ADH_zinc_N PF00107.21 KKK23185.1 - 1e-30 105.9 0.0 1.7e-30 105.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KKK23185.1 - 1.1e-20 74.7 0.0 2.3e-20 73.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KKK23185.1 - 6.6e-11 41.9 0.0 3.5e-10 39.6 0.0 2.0 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Cpn10 PF00166.16 KKK23185.1 - 0.018 14.9 0.2 0.15 12.0 0.0 2.6 2 1 1 3 3 3 0 Chaperonin 10 Kd subunit OPT PF03169.10 KKK23186.1 - 8.9e-120 400.9 41.4 1e-119 400.7 28.7 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Beta-lactamase PF00144.19 KKK23187.1 - 3.4e-29 101.9 1.1 3.3e-28 98.6 0.8 2.0 1 1 0 1 1 1 1 Beta-lactamase IF-2B PF01008.12 KKK23188.1 - 6.4e-48 163.1 0.0 1.7e-47 161.7 0.0 1.6 1 1 0 1 1 1 1 Initiation factor 2 subunit family Adaptin_N PF01602.15 KKK23189.1 - 1.4e-106 356.9 0.0 2.3e-106 356.2 0.0 1.3 1 1 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 KKK23189.1 - 8.9e-11 41.9 1.5 0.0032 17.7 0.0 5.2 4 1 0 5 5 5 3 HEAT repeats HEAT PF02985.17 KKK23189.1 - 2.7e-08 33.1 0.0 0.043 13.9 0.0 5.5 6 0 0 6 6 6 2 HEAT repeat Arm PF00514.18 KKK23189.1 - 0.002 17.8 3.2 1.4 8.8 0.1 5.4 5 1 1 6 6 6 1 Armadillo/beta-catenin-like repeat Cohesin_HEAT PF12765.2 KKK23189.1 - 0.025 14.5 0.4 2.1 8.4 0.0 3.1 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion CLASP_N PF12348.3 KKK23189.1 - 0.037 13.3 0.6 9.1 5.5 0.0 3.4 3 1 1 4 4 4 0 CLASP N terminal Cnd1 PF12717.2 KKK23189.1 - 0.042 13.6 0.1 11 5.8 0.0 3.3 2 1 1 3 3 3 0 non-SMC mitotic condensation complex subunit 1 SDA1 PF05285.7 KKK23189.1 - 7.3 5.7 17.0 1 8.5 7.3 2.0 2 0 0 2 2 2 0 SDA1 Rho_GDI PF02115.12 KKK23190.1 - 9.3e-59 198.1 0.0 1e-58 198.0 0.0 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor KilA-N PF04383.8 KKK23191.1 - 0.00039 20.0 0.0 0.0032 17.0 0.0 2.2 1 1 0 1 1 1 1 KilA-N domain EF-1_beta_acid PF10587.4 KKK23191.1 - 0.019 15.1 6.2 0.11 12.6 4.3 2.5 1 0 0 1 1 1 0 Eukaryotic elongation factor 1 beta central acidic region TFIIA PF03153.8 KKK23191.1 - 9.7 5.9 15.4 18 5.1 10.6 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Nuf2 PF03800.9 KKK23192.1 - 3.3e-45 153.6 0.7 1.2e-44 151.8 0.0 2.3 2 0 0 2 2 2 1 Nuf2 family Reo_sigmaC PF04582.7 KKK23192.1 - 0.27 10.3 9.4 1.5 7.9 3.6 2.4 1 1 1 2 2 2 0 Reovirus sigma C capsid protein STAT_alpha PF01017.15 KKK23192.1 - 5.8 6.5 31.6 0.2 11.3 7.5 2.5 2 0 0 2 2 2 0 STAT protein, all-alpha domain Bacillus_HBL PF05791.6 KKK23192.1 - 6.8 6.0 21.6 2 7.7 0.6 3.5 2 1 1 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) Laminin_II PF06009.7 KKK23192.1 - 7.7 6.2 34.9 2 8.1 7.6 3.4 1 1 2 3 3 3 0 Laminin Domain II Metallophos PF00149.23 KKK23194.1 - 2.6e-41 141.2 0.4 3.3e-41 140.8 0.3 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Clp1 PF06807.9 KKK23195.1 - 3.4e-13 49.7 0.0 4.4e-07 29.8 0.0 2.6 2 1 0 2 2 2 2 Pre-mRNA cleavage complex II protein Clp1 MobB PF03205.9 KKK23195.1 - 3.8e-06 26.6 0.0 6.5e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B ATP_bind_1 PF03029.12 KKK23195.1 - 4.6e-05 23.0 0.0 0.00025 20.6 0.0 1.9 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.18 KKK23195.1 - 5.8e-05 23.0 0.0 0.00029 20.7 0.0 2.1 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.1 KKK23195.1 - 0.023 14.6 0.0 0.045 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_35 PF14516.1 KKK23195.1 - 0.025 13.2 0.0 0.038 12.6 0.0 1.1 1 0 0 1 1 1 0 AAA-like domain SRPRB PF09439.5 KKK23195.1 - 0.11 11.6 0.0 0.22 10.7 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit FeoB_N PF02421.13 KKK23195.1 - 0.2 10.9 0.4 9.5 5.4 0.0 3.2 4 0 0 4 4 4 0 Ferrous iron transport protein B Polysacc_deac_1 PF01522.16 KKK23196.1 - 1.3e-21 76.4 0.0 1.6e-20 72.9 0.0 2.2 2 0 0 2 2 2 1 Polysaccharide deacetylase Ribonuc_2-5A PF06479.7 KKK23196.1 - 0.064 13.0 0.0 7.5 6.4 0.0 2.4 2 0 0 2 2 2 0 Ribonuclease 2-5A Ras PF00071.17 KKK23198.1 - 4.1e-51 172.5 0.6 2.8e-50 169.8 0.4 1.9 1 1 0 1 1 1 1 Ras family Miro PF08477.8 KKK23198.1 - 6e-16 59.0 0.2 1.6e-14 54.3 0.0 2.1 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 KKK23198.1 - 0.00069 18.9 0.1 0.0035 16.5 0.0 1.9 2 0 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 KKK23198.1 - 0.014 15.3 0.0 0.02 14.8 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase FeoB_N PF02421.13 KKK23198.1 - 0.025 13.8 0.2 0.42 9.8 0.0 2.4 2 1 1 3 3 3 0 Ferrous iron transport protein B AAA_25 PF13481.1 KKK23198.1 - 0.058 12.7 0.0 0.1 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain Ser_hydrolase PF06821.8 KKK23198.1 - 0.09 12.3 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase SRPRB PF09439.5 KKK23198.1 - 0.1 11.7 0.0 0.54 9.4 0.0 1.9 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Septin PF00735.13 KKK23198.1 - 0.14 11.1 0.0 0.22 10.4 0.0 1.3 1 0 0 1 1 1 0 Septin HAD_2 PF13419.1 KKK23199.1 - 9.1e-26 91.1 0.0 1.1e-25 90.8 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KKK23199.1 - 4.4e-06 27.2 0.0 1.4e-05 25.6 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KKK23199.1 - 0.00017 21.1 0.0 0.00029 20.5 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like Ribosomal_S28e PF01200.13 KKK23214.1 - 1.3e-32 111.3 3.2 1.4e-32 111.2 2.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e TPR_MLP1_2 PF07926.7 KKK23223.1 - 2.8e-29 101.5 33.7 2.8e-29 101.5 23.4 15.3 6 4 7 14 14 14 2 TPR/MLP1/MLP2-like protein CENP-F_leu_zip PF10473.4 KKK23223.1 - 0.0013 18.6 3.8 0.0013 18.6 2.7 15.4 5 3 8 15 15 15 7 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Uds1 PF15456.1 KKK23223.1 - 0.0063 16.4 11.3 0.0063 16.4 7.8 17.4 8 6 6 14 14 14 3 Up-regulated During Septation Ank_2 PF12796.2 KKK23224.1 - 9.5e-49 163.6 8.1 3.4e-17 62.5 1.7 4.1 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 KKK23224.1 - 5.6e-43 142.6 24.2 6e-07 28.9 0.1 8.3 8 0 0 8 8 8 7 Ankyrin repeat Ank_5 PF13857.1 KKK23224.1 - 4e-29 99.9 19.8 6.8e-08 32.5 0.1 7.9 2 2 7 9 9 9 6 Ankyrin repeats (many copies) Ank_4 PF13637.1 KKK23224.1 - 1.9e-28 98.2 11.9 6.4e-09 36.0 0.2 5.0 5 0 0 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 KKK23224.1 - 2.1e-28 95.5 15.0 0.00016 21.5 0.1 8.0 8 0 0 8 8 8 7 Ankyrin repeat RVP PF00077.15 KKK23224.1 - 0.064 13.1 0.1 91 3.0 0.0 3.7 4 0 0 4 4 4 0 Retroviral aspartyl protease gag-asp_proteas PF13975.1 KKK23224.1 - 0.13 12.1 3.5 4.5 7.1 0.0 3.8 4 0 0 4 4 4 0 gag-polyprotein putative aspartyl protease DHBP_synthase PF00926.14 KKK23225.1 - 1e-70 236.9 0.0 6.6e-70 234.2 0.0 1.8 1 1 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase TFIIE_beta PF02186.10 KKK23226.1 - 8.4e-06 25.6 0.0 4.2e-05 23.4 0.0 2.2 2 1 0 2 2 2 1 TFIIE beta subunit core domain DUF4419 PF14388.1 KKK23227.1 - 1.9e-81 273.5 0.1 2.2e-81 273.3 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4419) Ribosomal_L22e PF01776.12 KKK23230.1 - 3.8e-14 52.6 0.0 4.1e-14 52.5 0.0 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family E1_dh PF00676.15 KKK23256.1 - 9.6e-114 379.1 0.1 1.2e-113 378.8 0.0 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.1 KKK23256.1 - 0.0002 20.4 0.0 0.00039 19.4 0.0 1.5 2 0 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase DUF829 PF05705.9 KKK23264.1 - 9.6e-55 185.8 0.0 1.1e-54 185.6 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Rad51 PF08423.6 KKK23265.1 - 7.7e-24 83.9 0.0 1.5e-23 83.0 0.0 1.4 2 0 0 2 2 2 1 Rad51 AAA_25 PF13481.1 KKK23265.1 - 1.1e-11 44.5 0.0 2.1e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 KKK23265.1 - 1.7e-09 37.1 0.0 2.7e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 KaiC RecA PF00154.16 KKK23265.1 - 0.0033 16.5 0.0 0.0054 15.8 0.0 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein PAXNEB PF05625.6 KKK23265.1 - 0.12 11.1 0.0 0.19 10.5 0.0 1.2 1 0 0 1 1 1 0 PAXNEB protein Pox_A32 PF04665.7 KKK23265.1 - 0.12 11.6 0.1 0.23 10.7 0.1 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein DUF2075 PF09848.4 KKK23265.1 - 0.26 10.2 0.0 0.35 9.7 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Velvet PF11754.3 KKK23267.1 - 3.4e-63 212.9 0.0 5.5e-63 212.2 0.0 1.3 1 0 0 1 1 1 1 Velvet factor Ank PF00023.25 KKK23268.1 - 8e-13 47.5 2.3 1.5e-06 27.6 0.5 2.8 2 0 0 2 2 2 2 Ankyrin repeat TIG PF01833.19 KKK23268.1 - 1.7e-11 43.9 1.7 2.7e-11 43.2 0.1 2.1 2 0 0 2 2 2 1 IPT/TIG domain Ank_2 PF12796.2 KKK23268.1 - 6.6e-11 42.4 0.0 1.3e-10 41.4 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KKK23268.1 - 2.5e-09 37.0 0.4 2.3e-07 30.8 0.2 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 KKK23268.1 - 6.2e-08 32.9 0.4 1.2e-06 28.8 0.1 2.4 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 KKK23268.1 - 8.7e-08 31.6 0.4 0.0014 18.7 0.2 2.7 2 0 0 2 2 2 2 Ankyrin repeat Glyco_hydro_61 PF03443.9 KKK23269.1 - 6e-86 287.7 0.8 6e-86 287.7 0.6 1.9 2 0 0 2 2 2 1 Glycosyl hydrolase family 61 FA_desaturase PF00487.19 KKK23270.1 - 5.1e-26 91.6 17.8 9.1e-26 90.8 12.3 1.4 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.3 KKK23270.1 - 1.6e-05 24.9 0.0 3e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) MARVEL PF01284.18 KKK23270.1 - 0.45 10.3 4.8 4.4 7.1 2.0 2.3 2 0 0 2 2 2 0 Membrane-associating domain TRAPPC10 PF12584.3 KKK23271.1 - 3.8e-36 123.7 0.0 8.1e-36 122.7 0.0 1.6 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 Gryzun PF07919.7 KKK23271.1 - 0.0046 15.3 0.0 0.21 9.8 0.0 2.4 2 0 0 2 2 2 2 Gryzun, putative trafficking through Golgi Glyco_hydro_43 PF04616.9 KKK23272.1 - 2.2e-53 181.2 6.3 2.4e-29 102.3 0.4 2.2 1 1 1 2 2 2 2 Glycosyl hydrolases family 43 SUI1 PF01253.17 KKK23273.1 - 3.1e-17 62.1 0.1 8.3e-17 60.7 0.0 1.7 1 0 0 1 1 1 1 Translation initiation factor SUI1 Pkinase PF00069.20 KKK23273.1 - 1.3e-10 40.9 0.0 3.6e-10 39.4 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK23273.1 - 8.6e-06 25.0 0.0 1.8e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KKK23273.1 - 0.0031 17.2 1.8 0.0059 16.3 0.3 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 KKK23273.1 - 0.018 14.1 0.3 0.066 12.2 0.1 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KKK23273.1 - 0.021 13.7 0.0 0.063 12.2 0.0 1.7 2 0 0 2 2 2 0 Kinase-like Chitin_synth_2 PF03142.10 KKK23274.1 - 2.8e-22 78.8 12.5 3.9e-22 78.3 0.6 2.9 2 1 0 3 3 3 2 Chitin synthase Glyco_trans_2_3 PF13632.1 KKK23274.1 - 5.3e-16 58.9 6.3 5.3e-16 58.9 4.4 2.8 2 2 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 KKK23274.1 - 2.7e-15 56.7 0.0 4.7e-15 56.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 KKK23274.1 - 0.013 15.2 0.1 1.6 8.3 0.1 2.4 2 0 0 2 2 2 0 Glycosyl transferase family 2 Dabb PF07876.7 KKK23275.1 - 8e-12 45.4 0.0 9.1e-12 45.2 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain La PF05383.12 KKK23276.1 - 1.3e-18 66.5 0.1 2e-18 65.8 0.0 1.3 1 0 0 1 1 1 1 La domain RRM_6 PF14259.1 KKK23276.1 - 5.1e-08 32.7 0.0 1.1e-07 31.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KKK23276.1 - 2.1e-07 30.4 0.1 9e-07 28.4 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KKK23276.1 - 0.00097 18.9 0.0 0.0021 17.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FDF PF09532.5 KKK23277.1 - 5.7e-22 78.2 1.8 5.7e-22 78.2 1.2 1.4 2 0 0 2 2 2 1 FDF domain LSM14 PF12701.2 KKK23278.1 - 2.8e-34 116.7 0.0 4.9e-34 116.0 0.0 1.4 1 0 0 1 1 1 1 Scd6-like Sm domain SM-ATX PF14438.1 KKK23278.1 - 5e-05 23.1 0.0 9.8e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 Ataxin 2 SM domain PAT1 PF09770.4 KKK23278.1 - 4.1 5.5 31.4 5.7 5.0 21.8 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 WD40 PF00400.27 KKK23279.1 - 2.6e-32 109.5 4.3 1.9e-09 37.0 0.1 6.6 6 1 0 6 6 6 6 WD domain, G-beta repeat Nucleoporin_N PF08801.6 KKK23279.1 - 6.2e-06 25.2 0.1 0.23 10.1 0.0 3.3 2 1 1 4 4 4 2 Nup133 N terminal like Nup160 PF11715.3 KKK23279.1 - 0.00038 18.7 2.9 0.042 11.9 0.2 2.8 2 2 0 2 2 2 2 Nucleoporin Nup120/160 SGL PF08450.7 KKK23279.1 - 0.074 12.4 1.5 3.7 6.8 0.0 3.1 1 1 2 3 3 3 0 SMP-30/Gluconolaconase/LRE-like region DUF1902 PF08972.6 KKK23279.1 - 0.34 10.4 3.7 2.3 7.8 0.1 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF1902) Thioredox_DsbH PF03190.10 KKK23280.1 - 3.8e-72 241.3 0.2 7.4e-72 240.3 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function, DUF255 Thioredoxin_7 PF13899.1 KKK23280.1 - 4.3e-07 29.8 0.0 8.1e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.1 KKK23280.1 - 0.053 13.7 0.0 0.14 12.4 0.0 1.7 1 0 0 1 1 1 0 Thioredoxin-like domain Glyco_hydro_88 PF07470.8 KKK23280.1 - 0.058 12.4 0.1 1.7 7.5 0.0 2.9 2 1 1 3 3 3 0 Glycosyl Hydrolase Family 88 CAP PF00188.21 KKK23281.1 - 1.4e-18 67.5 2.2 1.4e-18 67.5 1.5 2.2 2 0 0 2 2 2 1 Cysteine-rich secretory protein family Carn_acyltransf PF00755.15 KKK23282.1 - 1.3e-170 568.4 0.0 9.3e-155 516.0 0.0 2.0 2 0 0 2 2 2 2 Choline/Carnitine o-acyltransferase zf-BED PF02892.10 KKK23285.1 - 0.096 12.4 2.7 1.3 8.8 0.0 2.5 2 0 0 2 2 2 0 BED zinc finger zf-C2H2_4 PF13894.1 KKK23285.1 - 2.1 8.8 6.3 0.38 11.2 0.7 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger Nbl1_Borealin_N PF10444.4 KKK23286.1 - 2.9e-21 74.6 6.2 6.2e-21 73.5 4.3 1.6 1 0 0 1 1 1 1 Nbl1 / Borealin N terminal Sybindin PF04099.7 KKK23287.1 - 2.8e-34 117.8 0.1 5.3e-20 71.5 0.0 2.3 2 0 0 2 2 2 2 Sybindin-like family Sedlin_N PF04628.8 KKK23287.1 - 0.0001 22.1 0.1 0.00021 21.1 0.0 1.4 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region zf-C2H2_4 PF13894.1 KKK23287.1 - 0.0014 18.7 16.0 0.012 15.9 1.4 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.21 KKK23287.1 - 3.2 8.2 12.7 9.6 6.7 1.0 3.8 3 0 0 3 3 3 0 Zinc finger, C2H2 type Sporozoite_P67 PF05642.6 KKK23287.1 - 9.6 3.9 16.5 19 2.9 11.4 1.4 1 0 0 1 1 1 0 Sporozoite P67 surface antigen VWA_2 PF13519.1 KKK23288.1 - 2.9e-11 43.7 0.1 4e-11 43.3 0.1 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain Ssl1 PF04056.9 KKK23288.1 - 3.3e-05 23.5 0.1 4.8e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Ssl1-like UIM PF02809.15 KKK23288.1 - 0.0028 17.1 0.6 0.012 15.1 0.4 2.2 1 0 0 1 1 1 1 Ubiquitin interaction motif DUF4097 PF13349.1 KKK23288.1 - 0.048 13.2 0.2 0.08 12.4 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4097) Alpha-L-AF_C PF06964.7 KKK23289.1 - 4.3e-35 121.0 0.5 7.6e-35 120.2 0.3 1.4 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminus MGDG_synth PF06925.6 KKK23289.1 - 0.11 12.4 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 Monogalactosyldiacylglycerol (MGDG) synthase ABC2_membrane PF01061.19 KKK23290.1 - 4.4e-94 313.5 65.9 6.5e-49 165.9 16.9 3.1 4 0 0 4 4 4 2 ABC-2 type transporter PDR_CDR PF06422.7 KKK23290.1 - 1.2e-38 130.8 5.1 3.5e-32 110.1 0.0 3.5 3 0 0 3 3 3 2 CDR ABC transporter ABC_tran PF00005.22 KKK23290.1 - 7.7e-36 123.4 0.0 1.5e-16 60.9 0.0 3.7 4 0 0 4 4 4 2 ABC transporter ABC_trans_N PF14510.1 KKK23290.1 - 1.3e-25 89.3 0.1 2.7e-25 88.2 0.1 1.6 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal ABC2_membrane_3 PF12698.2 KKK23290.1 - 4.4e-05 22.6 16.9 4.4e-05 22.6 11.7 3.5 3 1 1 4 4 3 1 ABC-2 family transporter protein AAA_25 PF13481.1 KKK23290.1 - 5.2e-05 22.7 0.0 0.004 16.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 KKK23290.1 - 0.0009 18.4 0.0 0.03 13.4 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_33 PF13671.1 KKK23290.1 - 0.005 16.7 0.0 0.82 9.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain cobW PF02492.14 KKK23290.1 - 0.0055 16.1 0.9 0.045 13.1 0.1 2.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain SMC_N PF02463.14 KKK23290.1 - 0.0095 15.1 0.0 0.79 8.9 0.0 2.8 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 KKK23290.1 - 0.014 14.9 0.3 0.64 9.5 0.1 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_16 PF13191.1 KKK23290.1 - 0.036 14.0 0.1 0.39 10.6 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.1 KKK23290.1 - 0.054 13.6 0.1 11 6.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 KKK23290.1 - 0.062 13.6 0.0 0.66 10.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 KKK23290.1 - 0.1 12.0 0.0 0.38 10.1 0.0 1.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_19 PF13245.1 KKK23290.1 - 0.13 12.0 0.0 26 4.6 0.0 2.5 2 0 0 2 2 2 0 Part of AAA domain NACHT PF05729.7 KKK23290.1 - 0.14 11.7 2.5 10 5.7 0.0 3.1 3 0 0 3 3 3 0 NACHT domain AAA_17 PF13207.1 KKK23290.1 - 0.14 12.9 0.0 3 8.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain Miro PF08477.8 KKK23290.1 - 0.16 12.4 0.0 35 4.9 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein Acetyltransf_1 PF00583.19 KKK23292.1 - 0.019 14.9 0.0 0.04 13.9 0.0 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family Phage_holin_5 PF06946.6 KKK23297.1 - 1 9.5 10.1 0.13 12.4 0.3 2.8 3 0 0 3 3 3 0 Phage holin Bestrophin PF01062.16 KKK23298.1 - 8.9e-51 172.5 1.9 3.3e-49 167.4 1.3 2.1 1 1 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel DUF167 PF02594.11 KKK23301.1 - 2.3e-12 46.6 0.1 3.5e-06 26.8 0.0 2.2 2 0 0 2 2 2 2 Uncharacterised ACR, YggU family COG1872 DUF3638 PF12340.3 KKK23305.1 - 9.2e-104 345.4 1.5 2e-103 344.3 1.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) MFS_1 PF07690.11 KKK23306.1 - 1.4e-33 116.1 26.1 1.4e-33 116.1 18.1 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily TMEMspv1-c74-12 PF11044.3 KKK23306.1 - 0.16 11.5 0.0 0.65 9.5 0.0 2.1 1 0 0 1 1 1 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein CLTH PF10607.4 KKK23313.1 - 4.4e-36 123.7 0.0 7.4e-36 123.0 0.0 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain SPRY PF00622.23 KKK23313.1 - 7.2e-16 58.4 0.3 1.4e-15 57.4 0.2 1.4 1 0 0 1 1 1 1 SPRY domain LisH PF08513.6 KKK23313.1 - 0.0002 20.9 0.7 0.0005 19.7 0.1 2.0 2 0 0 2 2 2 1 LisH OpuAC PF04069.7 KKK23313.1 - 0.028 13.7 0.6 1.3 8.2 0.2 2.3 1 1 1 2 2 2 0 Substrate binding domain of ABC-type glycine betaine transport system E1_DerP2_DerF2 PF02221.10 KKK23323.1 - 2.2e-28 99.1 0.1 2.8e-28 98.8 0.1 1.1 1 0 0 1 1 1 1 ML domain TRP_N PF14558.1 KKK23323.1 - 0.0011 18.9 0.0 0.0019 18.2 0.0 1.6 1 1 0 1 1 1 1 ML-like domain NPCBM_assoc PF10633.4 KKK23323.1 - 0.064 13.3 0.1 0.91 9.6 0.0 2.3 2 0 0 2 2 2 0 NPCBM-associated, NEW3 domain of alpha-galactosidase Med10 PF09748.4 KKK23336.1 - 6.2e-45 152.1 0.1 7.3e-45 151.9 0.0 1.0 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex DUF3877 PF12993.2 KKK23336.1 - 0.047 13.2 0.0 0.055 13.0 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function, E. rectale Gene description (DUF3877) Pkinase PF00069.20 KKK23337.1 - 1.7e-38 132.2 0.0 2.5e-38 131.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK23337.1 - 1.9e-28 99.2 0.0 2.7e-28 98.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KKK23337.1 - 0.0038 16.2 0.0 0.0065 15.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Utp14 PF04615.8 KKK23338.1 - 0.44 8.6 60.0 0.6 8.2 41.6 1.0 1 0 0 1 1 1 0 Utp14 protein Amidase PF01425.16 KKK23339.1 - 1.4e-80 271.2 0.0 1.7e-80 271.0 0.0 1.1 1 0 0 1 1 1 1 Amidase AT_hook PF02178.14 KKK23340.1 - 0.06 13.0 21.7 0.58 10.0 4.2 3.1 2 0 0 2 2 2 0 AT hook motif COPI_C PF06957.6 KKK23340.1 - 0.23 9.9 2.1 0.42 9.0 1.5 1.3 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus XPG_I PF00867.13 KKK23341.1 - 1.8e-22 79.2 0.1 6e-22 77.5 0.0 2.0 2 0 0 2 2 2 1 XPG I-region DUF1961 PF09224.6 KKK23341.1 - 0.15 11.1 0.0 0.27 10.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1961) adh_short_C2 PF13561.1 KKK23342.1 - 6e-29 101.5 0.0 7.8e-29 101.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KKK23342.1 - 9.6e-28 97.1 0.0 3.1e-27 95.5 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KKK23342.1 - 3.2e-08 33.4 0.0 9.4e-08 31.9 0.0 1.8 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 KKK23342.1 - 4.8e-05 22.8 0.0 6.5e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.5 KKK23342.1 - 0.071 12.2 0.0 0.087 11.9 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) CENP-K PF11802.3 KKK23342.1 - 0.079 12.1 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Centromere-associated protein K p450 PF00067.17 KKK23343.1 - 4.7e-39 134.1 0.0 6.5e-39 133.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Aldose_epim PF01263.15 KKK23345.1 - 9.9e-50 169.3 0.0 1.3e-49 168.9 0.0 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase Fer2_4 PF13510.1 KKK23345.1 - 0.0046 16.7 0.1 0.78 9.5 0.0 2.4 2 0 0 2 2 2 2 2Fe-2S iron-sulfur cluster binding domain Cpn60_TCP1 PF00118.19 KKK23346.1 - 7.9e-156 519.4 0.0 8.9e-156 519.2 0.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family CFEM PF05730.6 KKK23347.1 - 0.00024 20.8 5.5 0.00024 20.8 3.8 3.4 3 0 0 3 3 3 1 CFEM domain Tme5_EGF_like PF09064.5 KKK23347.1 - 0.77 9.4 5.1 0.4 10.3 1.3 2.2 2 0 0 2 2 2 0 Thrombomodulin like fifth domain, EGF-like MFS_1 PF07690.11 KKK23348.1 - 6.6e-23 80.9 56.4 1.4e-21 76.6 39.1 2.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KKK23348.1 - 1.2e-10 40.5 15.3 1.2e-10 40.5 10.6 3.3 3 0 0 3 3 3 1 Sugar (and other) transporter DUF2752 PF10825.3 KKK23351.1 - 0.00012 21.9 1.6 0.00021 21.2 1.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2752) MLANA PF14991.1 KKK23351.1 - 0.1 12.6 3.8 0.85 9.6 0.1 2.8 2 1 1 3 3 3 0 Protein melan-A Zn_clus PF00172.13 KKK23352.1 - 1.8e-06 27.7 9.9 1.8e-06 27.7 6.8 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KKK23352.1 - 0.0035 16.2 0.2 0.011 14.6 0.1 1.8 1 0 0 1 1 1 1 Fungal specific transcription factor domain LZ_Tnp_IS66 PF13007.2 KKK23352.1 - 0.017 15.7 1.3 0.037 14.6 0.9 1.6 1 0 0 1 1 1 0 Transposase C of IS166 homeodomain HSBP1 PF06825.7 KKK23352.1 - 0.063 12.8 1.2 0.14 11.7 0.1 2.0 2 0 0 2 2 2 0 Heat shock factor binding protein 1 N_NLPC_P60 PF12912.2 KKK23352.1 - 0.097 12.7 0.6 0.19 11.8 0.4 1.4 1 0 0 1 1 1 0 NLPC_P60 stabilising domain, N term ADH_zinc_N PF00107.21 KKK23353.1 - 1.5e-18 66.5 0.0 2.4e-18 65.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KKK23353.1 - 4.7e-12 46.8 0.0 9.4e-12 45.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Actin PF00022.14 KKK23354.1 - 3.5e-23 81.6 0.0 6.8e-20 70.8 0.0 3.1 2 1 0 2 2 2 2 Actin DUF1168 PF06658.7 KKK23355.1 - 1.6e-43 147.6 10.9 2.2e-43 147.1 7.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) Peptidase_S49_N PF08496.5 KKK23355.1 - 5.6 6.7 5.4 8.2 6.2 3.7 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal ADH_zinc_N PF00107.21 KKK23356.1 - 1.2e-08 34.5 0.8 0.0033 16.9 0.0 2.9 3 0 0 3 3 3 2 Zinc-binding dehydrogenase ADH_N PF08240.7 KKK23356.1 - 8.6e-07 28.6 0.0 4.2e-06 26.4 0.0 2.2 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain UQ_con PF00179.21 KKK23357.1 - 2.1e-22 79.0 0.0 3.7e-22 78.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Cupin_2 PF07883.6 KKK23358.1 - 0.0008 18.8 0.3 0.059 12.8 0.1 2.2 2 0 0 2 2 2 2 Cupin domain SPOC PF07744.8 KKK23358.1 - 0.001 19.5 0.0 0.0015 18.9 0.0 1.3 1 0 0 1 1 1 1 SPOC domain MannoseP_isomer PF01050.13 KKK23358.1 - 0.033 13.7 0.3 0.054 13.1 0.2 1.3 1 1 0 1 1 1 0 Mannose-6-phosphate isomerase Pyr_redox_3 PF13738.1 KKK23359.1 - 3e-21 76.4 0.0 6.9e-21 75.2 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KKK23359.1 - 4.3e-10 38.4 0.0 5e-09 34.9 0.0 2.3 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 KKK23359.1 - 2e-07 30.9 0.0 5.8e-07 29.4 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 KKK23359.1 - 0.00014 21.6 1.7 0.00031 20.5 0.0 2.5 3 1 0 3 3 3 1 FAD-NAD(P)-binding K_oxygenase PF13434.1 KKK23359.1 - 0.00033 19.6 0.0 0.0024 16.8 0.0 2.3 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) 2-Hacid_dh_C PF02826.14 KKK23359.1 - 0.12 11.5 0.0 0.23 10.6 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain zf-PARP PF00645.13 KKK23360.1 - 2.6e-24 85.2 0.0 4.5e-24 84.4 0.0 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region NmrA PF05368.8 KKK23361.1 - 7.9e-25 87.4 0.0 9.9e-25 87.1 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KKK23361.1 - 8.8e-12 45.4 0.0 2.6e-11 43.8 0.0 1.8 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KKK23361.1 - 6.7e-07 28.9 0.9 6.7e-06 25.6 0.4 2.3 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 KKK23361.1 - 1.2e-05 25.3 0.5 6.1e-05 22.9 0.2 2.0 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KKK23361.1 - 2.4e-05 24.0 0.3 5.9e-05 22.7 0.1 1.7 2 0 0 2 2 2 1 KR domain Saccharop_dh PF03435.13 KKK23361.1 - 7.1e-05 21.9 0.2 0.0001 21.4 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase 3Beta_HSD PF01073.14 KKK23361.1 - 0.003 16.3 0.1 0.0043 15.7 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 KKK23361.1 - 0.012 14.5 0.0 0.018 13.9 0.0 1.3 1 0 0 1 1 1 0 Male sterility protein Shikimate_DH PF01488.15 KKK23361.1 - 0.065 13.3 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.12 KKK23361.1 - 0.096 13.1 0.1 0.18 12.2 0.1 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Oxidored_nitro PF00148.14 KKK23361.1 - 0.13 10.9 0.0 0.19 10.3 0.0 1.2 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase DapB_N PF01113.15 KKK23361.1 - 0.15 11.9 0.3 0.31 10.9 0.2 1.6 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus AA_permease_2 PF13520.1 KKK23362.1 - 4.8e-29 101.1 50.2 5.6e-29 100.9 34.8 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KKK23362.1 - 1.5e-10 40.0 40.4 2e-10 39.6 28.0 1.1 1 0 0 1 1 1 1 Amino acid permease Abhydrolase_3 PF07859.8 KKK23363.1 - 9.2e-50 169.1 0.0 1.2e-49 168.7 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 KKK23363.1 - 4.5e-08 32.2 0.0 1e-07 31.1 0.0 1.5 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 KKK23363.1 - 0.00039 20.1 0.0 0.00055 19.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2424 PF10340.4 KKK23363.1 - 0.11 11.1 0.0 0.2 10.2 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2424) Esterase_phd PF10503.4 KKK23363.1 - 0.13 11.4 0.2 6.6 5.9 0.0 2.2 2 0 0 2 2 2 0 Esterase PHB depolymerase COesterase PF00135.23 KKK23364.1 - 6.6e-58 196.7 0.0 8.9e-58 196.2 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KKK23364.1 - 1.6e-10 40.9 0.2 3.8e-10 39.6 0.1 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KKK23364.1 - 0.00092 19.1 0.1 0.0023 17.8 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KKK23364.1 - 0.002 17.8 0.1 0.0053 16.5 0.0 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Esterase PF00756.15 KKK23364.1 - 0.02 14.3 0.0 0.14 11.5 0.0 2.0 1 1 0 1 1 1 0 Putative esterase SSF PF00474.12 KKK23367.1 - 5e-17 61.6 31.9 9.5e-17 60.7 22.1 1.5 1 0 0 1 1 1 1 Sodium:solute symporter family Dynein_light PF01221.13 KKK23368.1 - 1.4e-35 121.1 8.5 6.6e-28 96.5 0.7 2.0 1 1 1 2 2 2 2 Dynein light chain type 1 TFIID-31kDa PF02291.10 KKK23368.1 - 0.027 14.2 0.0 0.034 13.9 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit RRM_1 PF00076.17 KKK23369.1 - 9.7e-75 246.1 0.8 9.5e-20 70.0 0.0 5.5 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KKK23369.1 - 1.2e-64 214.1 0.1 1.5e-14 53.6 0.0 5.5 5 0 0 5 5 5 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KKK23369.1 - 3.7e-36 122.7 0.0 1.6e-11 43.8 0.0 5.5 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KKK23369.1 - 1.5e-07 31.0 0.0 0.37 10.6 0.0 3.9 3 0 0 3 3 3 3 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.3 KKK23369.1 - 0.00041 20.0 0.1 3.7 7.3 0.1 4.6 5 0 0 5 5 5 1 Limkain b1 TEA PF01285.13 KKK23370.1 - 5.6e-148 493.6 0.9 7.2e-148 493.3 0.6 1.1 1 0 0 1 1 1 1 TEA/ATTS domain family DUF3565 PF12088.3 KKK23370.1 - 0.024 14.3 0.0 0.29 10.9 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3565) Myb_DNA-binding PF00249.26 KKK23370.1 - 0.079 13.0 0.2 0.33 11.0 0.1 2.2 1 1 0 1 1 1 0 Myb-like DNA-binding domain Aldo_ket_red PF00248.16 KKK23371.1 - 1.2e-49 168.7 0.0 1.3e-49 168.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Oest_recep PF02159.10 KKK23372.1 - 0.003 17.6 0.7 0.0051 16.9 0.5 1.3 1 0 0 1 1 1 1 Oestrogen receptor DUF1330 PF07045.6 KKK23372.1 - 0.13 12.1 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1330) PAT1 PF09770.4 KKK23373.1 - 3.9 5.6 11.7 4 5.5 8.1 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 LRR_4 PF12799.2 KKK23374.1 - 4.1e-23 80.5 12.1 1.6e-10 40.3 2.5 3.1 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KKK23374.1 - 4.6e-14 51.9 29.9 4.4e-07 29.5 4.7 2.8 1 1 3 4 4 4 4 Leucine rich repeat LRR_6 PF13516.1 KKK23374.1 - 1.6e-11 42.9 6.2 0.0063 16.4 0.0 5.2 3 2 2 5 5 5 2 Leucine Rich repeat LRR_1 PF00560.28 KKK23374.1 - 2.1e-11 42.1 10.9 0.038 13.9 0.4 5.3 5 0 0 5 5 5 4 Leucine Rich Repeat LRR_7 PF13504.1 KKK23374.1 - 1e-08 33.9 7.6 0.21 11.9 0.0 5.2 4 1 1 5 5 5 3 Leucine rich repeat LRR_9 PF14580.1 KKK23374.1 - 1.3e-05 24.8 1.3 0.043 13.3 0.0 2.2 1 1 1 2 2 2 2 Leucine-rich repeat DUF1473 PF07341.6 KKK23374.1 - 0.022 14.2 0.6 0.17 11.4 0.1 1.9 1 1 0 2 2 2 0 Protein of unknown function (DUF1473) DUF325 PF03804.8 KKK23374.1 - 0.098 12.3 0.0 0.33 10.6 0.0 1.9 1 1 1 2 2 2 0 Viral domain of unknown function DUF3744 PF12558.3 KKK23374.1 - 1.5 9.3 4.1 3.1 8.2 0.6 2.4 1 1 1 2 2 2 0 ATP-binding cassette cobalt transporter E1-E2_ATPase PF00122.15 KKK23376.1 - 1.9e-66 223.4 7.4 4.6e-65 218.8 5.1 2.6 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KKK23376.1 - 1.4e-46 158.2 6.8 1.4e-46 158.2 4.7 1.9 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KKK23376.1 - 2.3e-29 103.3 0.0 4.6e-28 99.1 0.0 2.8 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KKK23376.1 - 1.5e-21 76.1 0.0 3e-21 75.1 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 KKK23376.1 - 3.9e-17 61.4 0.0 1.2e-16 59.8 0.0 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 KKK23376.1 - 2.6e-15 57.1 0.3 8.6e-15 55.4 0.1 2.1 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KKK23376.1 - 2.6e-07 30.4 2.0 1e-05 25.2 0.6 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase eIF3_subunit PF08597.5 KKK23378.1 - 2.9e-66 223.5 31.0 3.3e-66 223.3 21.5 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit ATC_hydrolase PF14196.1 KKK23378.1 - 9.3 6.6 12.0 0.3 11.4 0.1 2.2 2 0 0 2 2 2 0 L-2-amino-thiazoline-4-carboxylic acid hydrolase 14-3-3 PF00244.15 KKK23379.1 - 9.8e-115 381.5 2.9 1.2e-114 381.2 2.0 1.0 1 0 0 1 1 1 1 14-3-3 protein DUF837 PF05769.6 KKK23379.1 - 0.016 14.7 1.4 7.8 5.9 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF837) TPR_12 PF13424.1 KKK23379.1 - 0.018 14.9 0.4 9.3 6.2 0.1 2.7 2 1 0 2 2 2 0 Tetratricopeptide repeat MCM_N PF14551.1 KKK23379.1 - 0.75 10.2 3.3 4.4 7.8 0.3 2.3 1 1 1 2 2 2 0 MCM N-terminal domain Sec39 PF08314.6 KKK23388.1 - 9.1e-251 833.7 0.1 1e-250 833.6 0.1 1.0 1 0 0 1 1 1 1 Secretory pathway protein Sec39 Ndufs5 PF10200.4 KKK23389.1 - 0.00061 19.7 0.1 0.00075 19.4 0.0 1.1 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa DUF3128 PF11326.3 KKK23389.1 - 0.0031 17.6 1.4 0.0064 16.5 1.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF3128) COX6B PF02297.12 KKK23389.1 - 0.016 15.1 0.2 0.029 14.4 0.2 1.4 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIb UPF0203 PF05254.7 KKK23389.1 - 0.19 11.5 2.5 0.36 10.7 1.8 1.4 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0203) Bap31 PF05529.7 KKK23407.1 - 0.76 9.2 3.6 1.1 8.6 2.5 1.2 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like V_ATPase_I PF01496.14 KKK23407.1 - 1.5 6.5 2.4 2 6.1 1.6 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family HAUS6_N PF14661.1 KKK23407.1 - 1.8 7.8 6.9 2.9 7.2 4.8 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus IncA PF04156.9 KKK23407.1 - 3.1 7.3 7.3 4.5 6.8 5.0 1.2 1 0 0 1 1 1 0 IncA protein bZIP_2 PF07716.10 KKK23407.1 - 6.4 6.6 15.8 21 5.0 10.9 1.8 1 1 0 1 1 1 0 Basic region leucine zipper UPF0449 PF15136.1 KKK23407.1 - 6.6 7.0 9.1 0.31 11.2 2.2 1.9 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 His_Phos_2 PF00328.17 KKK23408.1 - 3.4e-61 207.5 0.0 3.8e-61 207.3 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Beta_protein PF14350.1 KKK23408.1 - 0.12 11.5 0.0 0.54 9.3 0.0 2.0 1 1 1 2 2 2 0 Beta protein Ribosomal_60s PF00428.14 KKK23409.1 - 0.054 13.8 0.2 0.054 13.8 0.1 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein CUE PF02845.11 KKK23410.1 - 2.7e-12 45.9 0.0 4.6e-12 45.1 0.0 1.4 1 0 0 1 1 1 1 CUE domain UBA PF00627.26 KKK23410.1 - 0.047 13.5 0.0 0.085 12.7 0.0 1.4 1 0 0 1 1 1 0 UBA/TS-N domain BTB_2 PF02214.17 KKK23412.1 - 3.2e-07 30.4 0.2 0.0036 17.4 0.0 2.5 2 0 0 2 2 2 2 BTB/POZ domain GMC_oxred_N PF00732.14 KKK23413.1 - 6.1e-36 124.0 1.1 2.2e-35 122.2 0.2 2.1 2 1 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KKK23413.1 - 2.7e-30 105.5 0.1 6.8e-29 101.0 0.0 2.3 2 0 0 2 2 2 1 GMC oxidoreductase DAO PF01266.19 KKK23413.1 - 4.8e-09 35.5 0.2 2.8e-05 23.1 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KKK23413.1 - 1.1e-07 31.0 0.2 4e-06 25.9 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 KKK23413.1 - 2.2e-05 24.4 0.1 0.00036 20.4 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KKK23413.1 - 3.7e-05 23.6 0.0 0.0002 21.2 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KKK23413.1 - 9.7e-05 21.5 0.1 0.00055 19.0 0.0 2.1 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.14 KKK23413.1 - 0.0014 17.7 0.0 0.0022 17.1 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 KKK23413.1 - 0.0032 15.9 0.1 0.0082 14.6 0.0 1.7 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.17 KKK23413.1 - 0.025 13.4 0.1 0.06 12.2 0.0 1.6 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_oxidored PF12831.2 KKK23413.1 - 0.036 13.1 0.2 0.056 12.5 0.2 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase IlvN PF07991.7 KKK23413.1 - 0.052 12.9 0.0 0.091 12.1 0.0 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain F-box-like PF12937.2 KKK23414.1 - 0.0016 18.1 1.1 0.0016 18.1 0.7 1.7 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KKK23414.1 - 0.021 14.4 1.0 0.055 13.1 0.7 1.6 1 0 0 1 1 1 0 F-box domain AMP-binding PF00501.23 KKK23415.1 - 1.4e-99 333.3 0.0 1.8e-99 332.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KKK23415.1 - 1.2e-11 45.3 0.0 2.4e-11 44.4 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Nol1_Nop2_Fmu PF01189.12 KKK23416.1 - 1.3e-11 44.4 0.0 1.9e-05 24.2 0.0 3.1 2 1 0 2 2 2 2 NOL1/NOP2/sun family DUF2693 PF10902.3 KKK23416.1 - 0.098 12.5 0.1 0.27 11.1 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2693) Acetyltransf_1 PF00583.19 KKK23417.1 - 9.2e-08 32.0 0.1 6e-06 26.1 0.0 2.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KKK23417.1 - 1.1e-06 28.6 0.7 3.3e-06 27.1 0.1 2.0 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_5 PF13444.1 KKK23417.1 - 8.2e-06 26.3 0.0 6.7e-05 23.4 0.0 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KKK23417.1 - 0.0017 18.1 0.2 0.0077 16.0 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 KKK23417.1 - 0.0021 17.9 0.0 0.0034 17.2 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_10 PF13673.1 KKK23417.1 - 0.0058 16.7 0.1 0.03 14.4 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KKK23417.1 - 0.058 13.1 0.0 8.9 6.1 0.0 2.4 2 0 0 2 2 2 0 FR47-like protein WD40 PF00400.27 KKK23427.1 - 4.3e-51 169.0 24.5 4.2e-13 48.6 0.2 6.2 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIIIC_delta PF12657.2 KKK23427.1 - 1e-06 28.6 14.8 0.0091 15.7 2.1 4.2 2 2 3 5 5 5 3 Transcription factor IIIC subunit delta N-term Sugar_tr PF00083.19 KKK23428.1 - 1.3e-60 205.3 19.7 4.8e-30 104.5 4.9 4.1 2 1 2 4 4 4 4 Sugar (and other) transporter MFS_1 PF07690.11 KKK23428.1 - 3.9e-10 38.9 34.0 0.00066 18.4 5.8 3.2 2 1 1 3 3 3 3 Major Facilitator Superfamily PspC PF04024.7 KKK23428.1 - 0.0067 15.8 1.0 0.0067 15.8 0.7 2.8 2 1 0 2 2 2 1 PspC domain Pkinase PF00069.20 KKK23429.1 - 8e-19 67.7 0.0 1.9e-18 66.5 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK23429.1 - 3.4e-08 32.8 0.0 1.1e-07 31.2 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase DUF3433 PF11915.3 KKK23429.1 - 0.03 14.4 0.0 0.1 12.7 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3433) Peptidase_M49 PF03571.10 KKK23430.1 - 3.1e-233 774.8 0.0 3.9e-233 774.5 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M49 SNF5 PF04855.7 KKK23431.1 - 4.9e-90 301.2 0.0 6.3e-90 300.9 0.0 1.1 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 GATA PF00320.22 KKK23431.1 - 0.00014 21.1 0.7 0.00044 19.5 0.5 2.0 1 0 0 1 1 1 1 GATA zinc finger Aminotran_4 PF01063.14 KKK23433.1 - 1.5e-29 103.1 0.0 2.1e-29 102.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class IV DUF3609 PF12259.3 KKK23434.1 - 0.075 11.6 0.0 0.12 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3609) ABC_tran PF00005.22 KKK23435.1 - 3.1e-48 163.5 0.6 3.5e-23 82.4 0.0 3.2 3 0 0 3 3 3 2 ABC transporter ABC_tran_2 PF12848.2 KKK23435.1 - 8.4e-21 73.6 8.1 8.4e-21 73.6 5.6 3.9 4 0 0 4 4 4 1 ABC transporter AAA_21 PF13304.1 KKK23435.1 - 1.5e-15 57.9 0.1 0.0026 17.7 0.0 4.7 5 0 0 5 5 4 3 AAA domain SMC_N PF02463.14 KKK23435.1 - 1.4e-10 40.7 1.0 0.025 13.7 0.0 4.6 4 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 KKK23435.1 - 2.9e-09 37.7 0.4 0.0049 17.6 0.0 3.3 3 0 0 3 3 3 2 AAA domain MMR_HSR1 PF01926.18 KKK23435.1 - 2.5e-06 27.4 0.0 0.019 14.8 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase DUF258 PF03193.11 KKK23435.1 - 3.8e-06 26.1 0.1 0.013 14.7 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_16 PF13191.1 KKK23435.1 - 4.4e-06 26.8 0.9 0.0075 16.2 0.1 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 KKK23435.1 - 6e-06 25.6 0.1 0.068 12.7 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain Miro PF08477.8 KKK23435.1 - 9.1e-06 26.1 0.2 0.05 14.1 0.0 3.0 3 0 0 3 3 2 2 Miro-like protein AAA_22 PF13401.1 KKK23435.1 - 2.1e-05 24.6 0.1 0.21 11.7 0.0 3.1 2 2 0 2 2 2 2 AAA domain AAA_18 PF13238.1 KKK23435.1 - 2.1e-05 24.8 4.2 0.16 12.2 0.0 3.7 5 0 0 5 5 2 2 AAA domain AAA_23 PF13476.1 KKK23435.1 - 9.9e-05 22.7 17.5 0.019 15.2 0.0 4.9 5 0 0 5 5 5 2 AAA domain AAA_28 PF13521.1 KKK23435.1 - 0.00013 22.0 2.8 0.092 12.7 0.0 3.0 3 0 0 3 3 2 2 AAA domain MobB PF03205.9 KKK23435.1 - 0.00024 20.8 0.1 0.7 9.5 0.1 2.8 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 KKK23435.1 - 0.0003 20.6 0.1 0.95 9.3 0.0 2.8 2 0 0 2 2 2 2 AAA domain Dynamin_N PF00350.18 KKK23435.1 - 0.00033 20.5 4.3 0.23 11.2 0.0 3.9 4 0 0 4 4 3 1 Dynamin family NACHT PF05729.7 KKK23435.1 - 0.00085 19.0 0.1 0.6 9.7 0.0 2.7 2 0 0 2 2 2 1 NACHT domain ArgK PF03308.11 KKK23435.1 - 0.0013 17.5 0.2 1.5 7.5 0.0 2.7 2 0 0 2 2 2 2 ArgK protein AAA_15 PF13175.1 KKK23435.1 - 0.0016 17.5 10.3 0.28 10.1 0.0 4.7 4 2 2 6 6 6 2 AAA ATPase domain AAA PF00004.24 KKK23435.1 - 0.0018 18.4 0.1 1.6 8.9 0.1 2.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 KKK23435.1 - 0.0043 16.9 0.0 6.4 6.6 0.0 3.2 3 0 0 3 3 2 0 AAA domain AAA_10 PF12846.2 KKK23435.1 - 0.0064 15.9 0.7 3.7 6.9 0.0 3.4 4 0 0 4 4 3 1 AAA-like domain AAA_25 PF13481.1 KKK23435.1 - 0.0071 15.7 0.0 2.1 7.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 KKK23435.1 - 0.0089 16.1 0.0 5.4 7.2 0.0 2.7 2 0 0 2 2 2 0 RNA helicase ATP-synt_ab PF00006.20 KKK23435.1 - 0.012 15.0 0.3 0.66 9.4 0.0 2.6 3 0 0 3 3 2 0 ATP synthase alpha/beta family, nucleotide-binding domain NTPase_1 PF03266.10 KKK23435.1 - 0.018 14.7 0.1 3.2 7.4 0.0 2.7 2 0 0 2 2 2 0 NTPase AAA_24 PF13479.1 KKK23435.1 - 0.025 14.1 0.1 4.5 6.8 0.1 2.5 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.4 KKK23435.1 - 0.027 13.9 0.0 9.7 5.6 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NB-ARC PF00931.17 KKK23435.1 - 0.029 13.2 0.0 4.2 6.1 0.0 2.6 2 0 0 2 2 2 0 NB-ARC domain cobW PF02492.14 KKK23435.1 - 0.057 12.8 2.5 3 7.2 0.3 3.0 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain AAA_5 PF07728.9 KKK23435.1 - 0.057 13.1 0.4 7.9 6.1 0.0 2.8 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) SbcCD_C PF13558.1 KKK23435.1 - 0.06 13.2 3.1 8.9 6.3 0.1 3.5 3 1 0 3 3 2 0 Putative exonuclease SbcCD, C subunit DUF87 PF01935.12 KKK23435.1 - 1.5 8.5 9.0 8.7 6.0 0.0 4.1 5 0 0 5 5 4 0 Domain of unknown function DUF87 Ribosomal_L22 PF00237.14 KKK23445.1 - 5.8e-16 58.3 2.7 1.5e-14 53.8 0.1 2.7 2 1 0 2 2 2 1 Ribosomal protein L22p/L17e His_Phos_1 PF00300.17 KKK23446.1 - 1.3e-16 61.0 0.0 2e-16 60.4 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) NifU_N PF01592.11 KKK23447.1 - 1.1e-47 161.1 0.0 1.4e-47 160.7 0.0 1.1 1 0 0 1 1 1 1 NifU-like N terminal domain Spermine_synth PF01564.12 KKK23449.1 - 4.5e-07 29.0 0.0 7.1e-07 28.4 0.0 1.2 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_30 PF05430.6 KKK23449.1 - 0.015 14.9 0.0 0.03 13.9 0.0 1.4 1 0 0 1 1 1 0 S-adenosyl-L-methionine-dependent methyltransferase DLIC PF05783.6 KKK23450.1 - 1.1e-38 133.1 0.2 4.5e-35 121.2 0.0 3.3 3 1 0 3 3 3 3 Dynein light intermediate chain (DLIC) DUF2052 PF09747.4 KKK23451.1 - 5e-36 124.3 9.3 1.6e-35 122.7 6.4 1.7 1 1 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) AMP-binding PF00501.23 KKK23452.1 - 1.6e-73 247.4 0.0 2.3e-73 247.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KKK23452.1 - 2.9e-16 60.1 0.0 8.7e-16 58.6 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain SET PF00856.23 KKK23452.1 - 7.3e-13 49.1 0.1 3.8e-11 43.5 0.0 3.1 2 1 0 2 2 2 1 SET domain WD40 PF00400.27 KKK23453.1 - 0.0023 17.7 0.0 0.0094 15.8 0.0 2.0 2 0 0 2 2 2 1 WD domain, G-beta repeat IKI3 PF04762.7 KKK23453.1 - 0.019 12.7 0.0 0.022 12.5 0.0 1.0 1 0 0 1 1 1 0 IKI3 family RRM_1 PF00076.17 KKK23454.1 - 2e-19 68.9 0.0 4.6e-19 67.8 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KKK23454.1 - 2.9e-12 46.3 0.0 7.1e-12 45.1 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KKK23454.1 - 2.6e-06 27.1 0.0 4.6e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KKK23455.1 - 6e-39 131.5 0.2 1.9e-11 43.4 0.0 4.1 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KKK23455.1 - 1.6e-32 111.2 0.3 1.2e-11 44.4 0.1 3.7 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KKK23455.1 - 7.8e-11 41.6 0.5 0.021 14.6 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KKK23455.1 - 2.2e-06 27.3 0.1 0.042 13.6 0.0 3.2 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 KKK23455.1 - 0.043 13.6 0.2 17 5.3 0.0 3.9 4 0 0 4 4 4 0 RNA binding motif NPHI_C PF08469.5 KKK23455.1 - 0.14 12.0 0.0 0.31 10.9 0.0 1.6 1 0 0 1 1 1 0 Nucleoside triphosphatase I C-terminal Peptidase_S9 PF00326.16 KKK23456.1 - 6.7e-54 182.3 0.0 1e-53 181.7 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KKK23456.1 - 1e-09 38.3 0.0 2.4e-09 37.0 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KKK23456.1 - 1.6e-08 34.7 0.5 3.8e-08 33.4 0.3 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 KKK23456.1 - 0.0052 15.5 0.5 0.0076 15.0 0.3 1.1 1 0 0 1 1 1 1 Carboxylesterase family PD40 PF07676.7 KKK23456.1 - 0.0054 16.3 1.6 0.96 9.1 0.2 2.9 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat Kri1 PF05178.7 KKK23457.1 - 0.019 15.2 1.2 0.027 14.7 0.9 1.2 1 0 0 1 1 1 0 KRI1-like family Abhydrolase_6 PF12697.2 KKK23459.1 - 3.5e-18 66.3 2.5 8.9e-18 64.9 1.8 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KKK23459.1 - 8.8e-05 22.1 0.2 0.00023 20.8 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KKK23459.1 - 0.00046 19.9 0.0 0.00065 19.4 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Cauli_DNA-bind PF03310.8 KKK23459.1 - 0.09 12.6 0.3 1.8 8.4 0.0 2.3 2 0 0 2 2 2 0 Caulimovirus DNA-binding protein p450 PF00067.17 KKK23460.1 - 3.8e-65 220.2 0.0 4.5e-65 219.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Motilin_assoc PF04643.7 KKK23460.1 - 0.15 11.6 0.0 0.37 10.3 0.0 1.7 1 0 0 1 1 1 0 Motilin/ghrelin-associated peptide Gp_dh_C PF02800.15 KKK23461.1 - 7.2e-21 74.2 0.0 8.5e-21 74.0 0.0 1.1 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain GCHY-1 PF02649.9 KKK23461.1 - 0.097 11.8 0.0 0.12 11.5 0.0 1.1 1 0 0 1 1 1 0 Type I GTP cyclohydrolase folE2 Pectinesterase PF01095.14 KKK23462.1 - 1e-172 572.6 71.1 4.9e-46 156.6 4.7 6.6 6 0 0 6 6 6 5 Pectinesterase DUF1788 PF08747.6 KKK23462.1 - 0.1 12.4 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1788) FAD_binding_3 PF01494.14 KKK23463.1 - 9e-13 47.9 0.6 1.5e-12 47.3 0.4 1.3 1 1 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 KKK23463.1 - 4.6e-06 26.9 0.2 2.4e-05 24.6 0.2 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KKK23463.1 - 2.4e-05 23.4 0.9 0.00017 20.6 0.2 2.1 1 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KKK23463.1 - 0.0005 20.0 0.1 0.0012 18.8 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 KKK23463.1 - 0.0018 17.4 0.2 0.0038 16.3 0.1 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.12 KKK23463.1 - 0.0096 15.0 0.0 0.018 14.1 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 KKK23463.1 - 0.013 15.4 0.1 0.024 14.4 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 KKK23463.1 - 0.015 14.7 0.1 0.026 13.9 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA FAD_binding_2 PF00890.19 KKK23463.1 - 0.02 13.7 0.2 0.047 12.5 0.0 1.7 2 0 0 2 2 2 0 FAD binding domain GIDA PF01134.17 KKK23463.1 - 0.067 12.0 0.2 0.11 11.3 0.1 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.16 KKK23463.1 - 0.099 12.2 0.1 0.16 11.4 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FA_hydroxylase PF04116.8 KKK23464.1 - 2.1e-14 53.8 12.5 2.1e-14 53.8 8.7 2.3 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Apq12 PF12716.2 KKK23464.1 - 0.17 11.5 2.8 0.41 10.3 1.9 1.7 1 0 0 1 1 1 0 Nuclear pore assembly and biogenesis Fungal_trans PF04082.13 KKK23465.1 - 3.1e-17 62.3 1.3 4.8e-17 61.7 0.9 1.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain Serpulina_VSP PF05540.6 KKK23466.1 - 0.006 15.4 0.1 0.0095 14.7 0.0 1.2 1 0 0 1 1 1 1 Serpulina hyodysenteriae variable surface protein DUF1102 PF06510.6 KKK23466.1 - 0.11 12.3 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1102) Sulfatase PF00884.18 KKK23467.1 - 9.3e-22 77.5 0.3 1.4e-21 76.9 0.2 1.2 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 KKK23467.1 - 1.2e-05 24.8 0.0 2e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase RHH_4 PF13467.1 KKK23467.1 - 0.098 12.5 0.0 0.26 11.1 0.0 1.7 1 0 0 1 1 1 0 Ribbon-helix-helix domain Metalloenzyme PF01676.13 KKK23467.1 - 0.14 11.5 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 Metalloenzyme superfamily DUF229 PF02995.12 KKK23467.1 - 0.21 9.9 0.0 0.31 9.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF229) HSDR_N_2 PF13588.1 KKK23469.1 - 0.0068 16.2 0.0 2.2 8.1 0.0 2.4 2 0 0 2 2 2 2 Type I restriction enzyme R protein N terminus (HSDR_N) Choline_kinase PF01633.15 KKK23469.1 - 0.057 12.9 0.0 0.88 9.0 0.0 2.4 2 0 0 2 2 2 0 Choline/ethanolamine kinase Sporozoite_P67 PF05642.6 KKK23469.1 - 0.062 11.1 0.2 0.086 10.6 0.1 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen APH PF01636.18 KKK23469.1 - 0.32 10.6 2.8 0.36 10.5 0.0 2.3 2 0 0 2 2 2 0 Phosphotransferase enzyme family MaoC_dehydratas PF01575.14 KKK23470.1 - 7.6e-26 89.9 0.0 1.6e-25 88.8 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.1 KKK23470.1 - 1e-07 31.7 0.1 2.7e-06 27.1 0.0 2.3 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase Polyketide_cyc2 PF10604.4 KKK23471.1 - 6.3e-07 29.6 0.0 7.6e-07 29.3 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Aldo_ket_red PF00248.16 KKK23528.1 - 2e-54 184.3 0.0 2.3e-54 184.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Thioredoxin PF00085.15 KKK23529.1 - 1.7e-28 98.3 0.1 2.1e-28 98.0 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 KKK23529.1 - 1.1e-08 35.0 0.0 2.8e-08 33.7 0.0 1.5 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.1 KKK23529.1 - 5.1e-08 33.0 0.1 3e-07 30.6 0.0 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Redoxin PF08534.5 KKK23529.1 - 2.4e-05 23.8 0.3 0.00038 20.0 0.1 2.0 1 1 1 2 2 2 1 Redoxin Thioredoxin_9 PF14595.1 KKK23529.1 - 2.8e-05 23.6 0.0 3e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.16 KKK23529.1 - 3.8e-05 23.3 0.0 4.8e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_7 PF13899.1 KKK23529.1 - 0.0014 18.6 0.1 0.0027 17.6 0.1 1.5 1 1 0 1 1 1 1 Thioredoxin-like TraF PF13728.1 KKK23529.1 - 0.0057 16.1 0.0 0.0065 15.9 0.0 1.2 1 0 0 1 1 1 1 F plasmid transfer operon protein Phosducin PF02114.11 KKK23529.1 - 0.032 12.9 0.0 0.038 12.7 0.0 1.1 1 0 0 1 1 1 0 Phosducin Thioredoxin_4 PF13462.1 KKK23529.1 - 0.059 13.3 0.0 1.8 8.5 0.0 2.1 1 1 1 2 2 2 0 Thioredoxin DUF953 PF06110.6 KKK23529.1 - 0.15 11.4 0.1 0.79 9.1 0.1 1.9 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) Ank_2 PF12796.2 KKK23530.1 - 8.4e-67 221.5 0.0 3.1e-17 62.6 0.2 5.5 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KKK23530.1 - 3.1e-55 183.6 1.1 2.9e-09 37.1 0.0 8.0 4 2 4 8 8 8 8 Ankyrin repeats (many copies) Ank PF00023.25 KKK23530.1 - 2.7e-51 168.9 0.1 0.00098 18.8 0.1 12.2 12 0 0 12 12 12 10 Ankyrin repeat Ank_5 PF13857.1 KKK23530.1 - 5.7e-44 147.1 1.2 4.3e-07 29.9 0.0 9.2 2 2 8 10 10 10 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 KKK23530.1 - 3.2e-43 141.4 0.0 0.00078 19.4 0.0 12.4 12 0 0 12 12 12 9 Ankyrin repeat Aa_trans PF01490.13 KKK23530.1 - 5.7e-39 133.7 32.0 7.8e-39 133.3 22.2 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein F-box-like PF12937.2 KKK23530.1 - 2e-06 27.3 0.1 6.6e-06 25.7 0.0 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KKK23530.1 - 0.00011 21.7 0.0 0.00024 20.6 0.0 1.6 1 0 0 1 1 1 1 F-box domain DUF2678 PF10856.3 KKK23530.1 - 8.1 6.2 7.9 6.2 6.5 1.8 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2678) adh_short_C2 PF13561.1 KKK23531.1 - 9.7e-18 64.8 0.1 1.8e-17 63.9 0.1 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KKK23531.1 - 2.8e-17 63.1 0.1 4.6e-17 62.4 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KKK23531.1 - 0.00024 20.8 0.1 0.00038 20.1 0.0 1.3 1 1 0 1 1 1 1 KR domain Fungal_trans PF04082.13 KKK23532.1 - 5.9e-10 38.4 0.8 9.2e-10 37.8 0.5 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK23532.1 - 6.5e-08 32.3 7.1 1.1e-07 31.5 4.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Alba PF01918.16 KKK23532.1 - 0.2 11.2 0.1 0.98 9.0 0.0 2.1 2 0 0 2 2 2 0 Alba MFS_1 PF07690.11 KKK23533.1 - 1e-35 123.1 67.1 2.9e-25 88.7 23.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Cytochrom_B_N_2 PF13631.1 KKK23533.1 - 0.014 15.2 2.4 0.014 15.2 1.6 3.1 2 1 0 3 3 3 0 Cytochrome b(N-terminal)/b6/petB MFS_1_like PF12832.2 KKK23533.1 - 0.024 14.4 0.7 0.024 14.4 0.5 3.2 3 2 2 5 5 5 0 MFS_1 like family Pox_A9 PF04835.7 KKK23533.1 - 0.32 10.9 2.8 0.29 11.0 0.3 2.2 2 0 0 2 2 2 0 A9 protein conserved region DUF3681 PF12442.3 KKK23533.1 - 7.2 6.8 10.5 1.2 9.3 1.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3681) Pyr_redox PF00070.22 KKK23534.1 - 8.1e-09 35.7 0.0 2.7e-06 27.6 0.0 2.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KKK23534.1 - 1.9e-08 34.4 0.0 1.7e-06 28.0 0.0 2.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KKK23534.1 - 3.5e-05 23.9 0.2 0.042 13.8 0.0 2.8 2 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KKK23534.1 - 0.0082 15.0 5.0 0.72 8.6 0.1 2.9 3 1 0 3 3 3 2 FAD dependent oxidoreductase DUF2937 PF11157.3 KKK23534.1 - 0.071 12.4 0.7 0.94 8.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) K_oxygenase PF13434.1 KKK23534.1 - 0.21 10.4 0.0 0.39 9.5 0.0 1.3 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Prenyltrans_2 PF13249.1 KKK23535.1 - 1e-32 112.8 0.2 1e-17 64.5 0.0 5.6 3 2 1 5 5 5 4 Prenyltransferase-like Prenyltrans_1 PF13243.1 KKK23535.1 - 7.4e-31 106.3 0.1 5.9e-15 55.2 0.0 5.7 5 1 1 6 6 6 4 Prenyltransferase-like Prenyltrans PF00432.16 KKK23535.1 - 9e-19 66.7 14.2 6.8e-06 25.5 0.0 6.5 6 0 0 6 6 6 4 Prenyltransferase and squalene oxidase repeat Pec_lyase PF09492.5 KKK23535.1 - 1.3e-06 27.8 0.0 0.052 12.7 0.0 3.5 4 0 0 4 4 4 3 Pectic acid lyase A2M_comp PF07678.9 KKK23535.1 - 0.00085 18.6 0.2 2 7.5 0.0 3.9 4 1 0 4 4 4 2 A-macroglobulin complement component WD40 PF00400.27 KKK23536.1 - 7.7e-15 54.1 0.6 1.8e-14 52.9 0.4 1.7 1 0 0 1 1 1 1 WD domain, G-beta repeat NACHT PF05729.7 KKK23536.1 - 1.3e-10 41.2 0.1 3.1e-10 39.9 0.1 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KKK23536.1 - 2.5e-08 34.1 0.2 2.3e-07 30.9 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain Arch_ATPase PF01637.13 KKK23536.1 - 2.7e-06 27.2 0.0 1.4e-05 24.9 0.0 2.0 2 0 0 2 2 2 1 Archaeal ATPase AAA_22 PF13401.1 KKK23536.1 - 3.4e-06 27.2 0.8 0.00021 21.4 0.0 3.5 3 1 1 4 4 4 1 AAA domain NB-ARC PF00931.17 KKK23536.1 - 7.6e-05 21.6 0.4 0.00018 20.4 0.0 1.8 2 0 0 2 2 2 1 NB-ARC domain AAA PF00004.24 KKK23536.1 - 0.00066 19.8 0.0 0.0019 18.3 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) APS_kinase PF01583.15 KKK23536.1 - 0.0021 17.7 0.1 0.0044 16.7 0.0 1.5 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_17 PF13207.1 KKK23536.1 - 0.026 15.3 0.1 0.11 13.2 0.0 2.3 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.1 KKK23536.1 - 0.041 14.1 0.1 0.32 11.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 KKK23536.1 - 0.044 13.3 0.1 0.2 11.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 KKK23536.1 - 0.072 13.2 0.0 0.18 11.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_19 PF13245.1 KKK23536.1 - 0.14 11.9 0.0 0.33 10.7 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain KAP_NTPase PF07693.9 KKK23536.1 - 0.72 8.7 7.4 0.34 9.8 0.7 2.8 2 1 1 3 3 3 0 KAP family P-loop domain Pyr_redox_3 PF13738.1 KKK23537.1 - 1.6e-13 51.2 0.0 3.2e-13 50.1 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KKK23537.1 - 6.7e-06 26.1 0.0 0.00014 21.8 0.0 2.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KKK23537.1 - 6.2e-05 22.8 0.0 0.0064 16.2 0.0 2.6 2 0 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 KKK23537.1 - 0.00073 19.5 0.0 0.0021 18.0 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.14 KKK23537.1 - 0.001 17.3 0.0 0.015 13.5 0.0 2.6 3 1 0 3 3 3 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 KKK23537.1 - 0.045 12.6 0.0 0.12 11.2 0.0 1.7 2 1 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.9 KKK23537.1 - 0.14 10.6 0.0 3.8 5.8 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein Arylsulfotran_2 PF14269.1 KKK23538.1 - 1.5e-45 155.6 0.0 2.1e-45 155.1 0.0 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Transketolase_C PF02780.15 KKK23538.1 - 5.3e-29 100.6 0.3 1.2e-28 99.5 0.0 1.7 2 0 0 2 2 2 1 Transketolase, C-terminal domain Transket_pyr PF02779.19 KKK23538.1 - 2.6e-19 69.3 3.2 6.6e-09 35.5 0.0 3.4 1 1 2 3 3 3 3 Transketolase, pyrimidine binding domain Arylsulfotrans PF05935.6 KKK23538.1 - 5.2e-15 54.9 1.0 9.3e-15 54.0 0.7 1.3 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Transketolase_N PF00456.16 KKK23539.1 - 7.2e-117 389.9 0.0 3.9e-116 387.5 0.0 1.9 1 1 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 KKK23539.1 - 1e-40 139.1 0.1 2.7e-40 137.7 0.1 1.8 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 KKK23539.1 - 6.7e-07 29.2 0.0 1.7e-06 27.9 0.0 1.7 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.1 KKK23539.1 - 8.2e-07 28.2 0.0 0.00027 19.9 0.0 2.2 1 1 1 2 2 2 2 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.15 KKK23539.1 - 7e-06 24.9 0.0 1.2e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component ADH_N PF08240.7 KKK23540.1 - 2.6e-28 97.9 1.2 2.6e-28 97.9 0.8 1.6 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KKK23540.1 - 2.4e-15 56.2 0.0 4.8e-15 55.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KKK23540.1 - 0.0019 19.0 0.0 0.0056 17.5 0.0 1.9 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Pyr_redox_3 PF13738.1 KKK23540.1 - 0.016 15.2 0.7 0.12 12.4 0.1 2.0 1 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 KKK23540.1 - 0.034 14.1 0.0 0.076 13.0 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain Pyr_redox_2 PF07992.9 KKK23540.1 - 0.042 13.7 0.1 0.085 12.7 0.0 1.6 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AdoHcyase_NAD PF00670.16 KKK23540.1 - 0.079 12.7 0.0 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Phosphoesterase PF04185.9 KKK23541.1 - 7.9e-71 239.2 0.1 1.1e-70 238.7 0.0 1.2 1 0 0 1 1 1 1 Phosphoesterase family Spc7_N PF15402.1 KKK23549.1 - 0 1206.4 62.4 0 1206.0 43.2 1.2 1 0 0 1 1 1 1 N-terminus of kinetochore NMS complex subunit Spc7 Spc7 PF08317.6 KKK23549.1 - 8.4e-128 425.6 5.4 1.7e-127 424.6 3.8 1.4 1 0 0 1 1 1 1 Spc7 kinetochore protein Sec8_exocyst PF04048.9 KKK23549.1 - 0.007 16.0 3.5 0.017 14.7 2.4 1.6 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain Gp_dh_C PF02800.15 KKK23549.1 - 0.051 13.0 0.4 0.14 11.6 0.0 1.8 2 0 0 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Pro-NT_NN PF07421.6 KKK23549.1 - 0.11 12.0 0.2 2.7 7.4 0.0 2.6 2 0 0 2 2 2 0 Neurotensin/neuromedin N precursor TMPIT PF07851.8 KKK23549.1 - 2 7.4 3.5 3.8 6.5 2.4 1.4 1 0 0 1 1 1 0 TMPIT-like protein V_ATPase_I PF01496.14 KKK23549.1 - 8 4.1 5.5 15 3.2 3.8 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Ribosomal_S17 PF00366.15 KKK23550.1 - 9e-31 105.7 1.2 1.3e-30 105.2 0.8 1.2 1 0 0 1 1 1 1 Ribosomal protein S17 ANTH PF07651.11 KKK23552.1 - 1.3e-61 207.7 0.6 1.7e-61 207.4 0.4 1.1 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.15 KKK23552.1 - 7.9e-06 25.7 0.1 5e-05 23.1 0.0 2.1 2 0 0 2 2 2 1 ENTH domain Fungal_trans_2 PF11951.3 KKK23553.1 - 0.088 11.3 0.5 1.6 7.2 0.0 2.2 2 0 0 2 2 2 0 Fungal specific transcription factor domain Grp1_Fun34_YaaH PF01184.14 KKK23554.1 - 8.2e-65 218.0 16.3 1.3e-64 217.4 11.3 1.3 1 1 0 1 1 1 1 GPR1/FUN34/yaaH family zf-C3HC4_3 PF13920.1 KKK23564.1 - 0.0014 18.2 11.9 0.0022 17.5 8.3 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DUF812 PF05667.6 KKK23564.1 - 0.47 8.8 0.7 0.71 8.2 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) zf-RING_6 PF14835.1 KKK23564.1 - 1 9.2 6.4 1.7 8.4 4.4 1.2 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-C3HC4_2 PF13923.1 KKK23564.1 - 1.3 9.1 12.5 2.2 8.3 8.6 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF2379 PF09543.5 KKK23568.1 - 0.018 15.0 0.7 0.13 12.1 0.3 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2379) Ran_BP1 PF00638.13 KKK23569.1 - 2.1e-50 169.8 2.0 2.1e-50 169.8 1.4 1.5 2 0 0 2 2 2 1 RanBP1 domain WH1 PF00568.18 KKK23569.1 - 1.6e-05 24.5 0.3 0.00013 21.6 0.2 2.1 1 1 0 1 1 1 1 WH1 domain FHIPEP PF00771.15 KKK23569.1 - 0.12 10.6 1.4 0.16 10.2 1.0 1.2 1 0 0 1 1 1 0 FHIPEP family CDC27 PF09507.5 KKK23569.1 - 0.14 11.3 16.5 0.2 10.8 11.4 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF4358 PF14270.1 KKK23569.1 - 0.23 11.3 5.5 3 7.7 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4358) Phasin PF05597.6 KKK23569.1 - 1.4 8.6 8.7 2.8 7.7 0.3 3.1 3 0 0 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) TMEM247 PF15444.1 KKK23569.1 - 2.7 7.7 6.0 4 7.2 4.1 1.2 1 0 0 1 1 1 0 Transmembrane protein 247 YEATS PF03366.11 KKK23570.1 - 9.1e-22 76.5 0.1 1.5e-21 75.8 0.0 1.4 1 0 0 1 1 1 1 YEATS family Fungal_trans PF04082.13 KKK23571.1 - 1e-19 70.4 1.2 1.3e-19 70.1 0.1 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 KKK23571.1 - 9.6e-07 28.7 18.2 0.0066 16.7 3.3 3.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KKK23571.1 - 3.5e-06 27.0 6.2 3.5e-06 27.0 4.3 3.0 3 0 0 3 3 3 1 Zinc-finger double domain Zn_clus PF00172.13 KKK23571.1 - 1e-05 25.3 9.6 1e-05 25.3 6.7 2.5 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_4 PF13894.1 KKK23571.1 - 0.0002 21.4 24.5 0.00051 20.1 2.6 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.2 KKK23571.1 - 0.012 15.8 0.9 0.012 15.8 0.6 1.9 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KKK23571.1 - 0.021 14.9 7.2 0.97 9.6 0.3 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding GvpG PF05120.7 KKK23572.1 - 0.042 13.6 0.3 0.091 12.5 0.2 1.5 1 0 0 1 1 1 0 Gas vesicle protein G DNA_ligase_A_M PF01068.16 KKK23574.1 - 9.6e-46 155.7 0.0 4.3e-45 153.5 0.0 2.1 2 0 0 2 2 2 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 KKK23574.1 - 6e-38 130.4 0.3 2e-37 128.7 0.0 2.1 3 0 0 3 3 3 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 KKK23574.1 - 3.3e-17 62.6 0.0 1.9e-16 60.1 0.0 2.5 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region BRCT PF00533.21 KKK23574.1 - 2.7e-13 49.8 0.0 3.5e-07 30.2 0.0 2.6 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain DNA_ligase_IV PF11411.3 KKK23574.1 - 0.00011 21.8 0.1 0.00028 20.5 0.0 1.7 1 0 0 1 1 1 1 DNA ligase IV PTCB-BRCT PF12738.2 KKK23574.1 - 0.026 14.3 0.1 4.4 7.2 0.0 2.6 2 0 0 2 2 2 0 twin BRCT domain mRNA_cap_enzyme PF01331.14 KKK23574.1 - 0.061 13.0 0.1 1.1 8.9 0.0 2.8 2 1 0 2 2 2 0 mRNA capping enzyme, catalytic domain DNA_ligase_OB_2 PF14743.1 KKK23574.1 - 0.1 12.3 0.4 6.1 6.6 0.3 2.6 1 1 0 1 1 1 0 DNA ligase OB-like domain RTA1 PF04479.8 KKK23575.1 - 1.7e-36 125.8 12.1 2.2e-36 125.4 8.4 1.2 1 0 0 1 1 1 1 RTA1 like protein Cyclin_N PF00134.18 KKK23575.1 - 0.0092 15.5 0.7 0.015 14.8 0.5 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain DUF3180 PF11377.3 KKK23575.1 - 0.62 9.9 10.2 0.95 9.3 3.3 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3180) Fungal_trans PF04082.13 KKK23576.1 - 1e-43 149.0 0.1 1.6e-43 148.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Acetyltransf_1 PF00583.19 KKK23577.1 - 1.7e-11 44.0 0.0 2.4e-11 43.4 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KKK23577.1 - 1.3e-07 31.6 0.0 1.3e-06 28.4 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KKK23577.1 - 0.0011 19.0 0.1 0.0074 16.4 0.0 2.1 1 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KKK23577.1 - 0.0071 16.1 0.0 0.014 15.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Fungal_trans PF04082.13 KKK23578.1 - 4.4e-11 42.1 0.3 1.2e-10 40.7 0.2 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Metallophos PF00149.23 KKK23580.1 - 6.4e-37 126.9 0.2 2.7e-29 102.0 0.1 2.1 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase EamA PF00892.15 KKK23581.1 - 6.9e-09 35.8 4.4 6.9e-09 35.8 3.1 3.1 3 1 0 3 3 3 2 EamA-like transporter family UAA PF08449.6 KKK23581.1 - 1.5e-07 30.6 7.4 1.5e-07 30.6 5.1 1.5 2 0 0 2 2 2 1 UAA transporter family EmrE PF13536.1 KKK23581.1 - 6.1e-05 23.2 6.8 6.1e-05 23.2 4.7 3.7 3 2 0 3 3 3 1 Multidrug resistance efflux transporter DUF914 PF06027.7 KKK23581.1 - 0.00025 19.9 10.1 0.00025 19.9 7.0 2.3 2 1 0 2 2 2 1 Eukaryotic protein of unknown function (DUF914) TPT PF03151.11 KKK23581.1 - 0.017 14.7 5.5 0.017 14.7 3.8 2.9 3 0 0 3 3 3 0 Triose-phosphate Transporter family Ras PF00071.17 KKK23582.1 - 8.1e-57 191.1 0.0 9.6e-57 190.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KKK23582.1 - 7.2e-20 71.6 0.0 1.1e-19 71.0 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KKK23582.1 - 3.7e-13 49.0 0.0 4.4e-13 48.8 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 KKK23582.1 - 3.7e-07 30.0 0.0 5e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KKK23582.1 - 1.3e-06 28.0 0.0 4e-05 23.1 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 KKK23582.1 - 1.7e-06 27.3 0.0 2.1e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.1 KKK23582.1 - 0.00044 20.4 0.0 0.00085 19.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 KKK23582.1 - 0.0013 17.9 0.1 0.0028 16.8 0.1 1.4 1 1 0 1 1 1 1 Protein of unknown function, DUF258 PduV-EutP PF10662.4 KKK23582.1 - 0.0019 17.7 0.1 0.078 12.4 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.12 KKK23582.1 - 0.0026 17.3 0.2 0.1 12.1 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein Arch_ATPase PF01637.13 KKK23582.1 - 0.0046 16.6 0.5 0.01 15.5 0.0 1.7 2 0 0 2 2 2 1 Archaeal ATPase Septin PF00735.13 KKK23582.1 - 0.0048 15.9 0.1 0.033 13.2 0.0 2.1 2 0 0 2 2 2 1 Septin AAA_10 PF12846.2 KKK23582.1 - 0.0058 16.1 0.2 0.017 14.5 0.1 1.6 1 1 0 2 2 2 1 AAA-like domain AAA_24 PF13479.1 KKK23582.1 - 0.0066 16.0 0.0 0.01 15.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain cobW PF02492.14 KKK23582.1 - 0.0071 15.8 0.0 0.04 13.3 0.0 1.9 1 1 1 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.10 KKK23582.1 - 0.011 15.4 0.0 0.017 14.8 0.0 1.3 1 0 0 1 1 1 0 NTPase AAA_16 PF13191.1 KKK23582.1 - 0.012 15.6 0.0 0.039 13.9 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain SRPRB PF09439.5 KKK23582.1 - 0.015 14.5 0.0 0.018 14.2 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_5 PF07728.9 KKK23582.1 - 0.015 15.0 0.0 0.029 14.1 0.0 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) MobB PF03205.9 KKK23582.1 - 0.027 14.1 0.2 0.079 12.6 0.0 1.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 KKK23582.1 - 0.12 12.0 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_14 PF13173.1 KKK23582.1 - 0.14 12.0 0.0 0.36 10.7 0.0 1.7 2 0 0 2 2 2 0 AAA domain FeoB_N PF02421.13 KKK23582.1 - 0.15 11.3 0.0 1.1 8.5 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B ATG16 PF08614.6 KKK23583.1 - 2.3e-44 151.5 14.0 1.5e-43 148.9 9.7 1.8 1 1 0 1 1 1 1 Autophagy protein 16 (ATG16) IncA PF04156.9 KKK23583.1 - 0.0029 17.2 4.6 0.0053 16.3 3.2 1.4 1 1 0 1 1 1 1 IncA protein AAA_13 PF13166.1 KKK23583.1 - 0.0048 15.4 0.8 0.0056 15.2 0.5 1.0 1 0 0 1 1 1 1 AAA domain DUF4201 PF13870.1 KKK23583.1 - 0.0059 16.0 9.3 0.018 14.5 6.4 1.7 1 1 1 2 2 2 1 Domain of unknown function (DUF4201) EMP24_GP25L PF01105.19 KKK23583.1 - 0.0073 16.0 0.8 0.36 10.5 0.0 2.1 1 1 1 2 2 2 1 emp24/gp25L/p24 family/GOLD Golgin_A5 PF09787.4 KKK23583.1 - 0.011 14.3 4.6 0.016 13.7 2.3 1.8 1 1 0 1 1 1 0 Golgin subfamily A member 5 Prefoldin_2 PF01920.15 KKK23583.1 - 0.013 15.2 4.0 0.93 9.2 0.1 2.3 1 1 1 2 2 2 0 Prefoldin subunit IFT57 PF10498.4 KKK23583.1 - 0.015 14.0 1.6 0.017 13.9 1.1 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Nup54 PF13874.1 KKK23583.1 - 0.016 14.8 6.9 0.22 11.2 1.1 2.2 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 FliJ PF02050.11 KKK23583.1 - 0.019 14.9 4.2 0.22 11.5 0.3 2.6 1 1 1 2 2 2 0 Flagellar FliJ protein APG6 PF04111.7 KKK23583.1 - 0.027 13.5 6.8 0.039 12.9 4.7 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Tropomyosin PF00261.15 KKK23583.1 - 0.052 12.6 10.2 0.12 11.4 7.0 1.6 1 1 0 1 1 1 0 Tropomyosin DUF874 PF05917.6 KKK23583.1 - 0.11 11.3 1.9 0.17 10.7 1.3 1.3 1 0 0 1 1 1 0 Helicobacter pylori protein of unknown function (DUF874) Spc7 PF08317.6 KKK23583.1 - 0.13 10.8 5.3 0.3 9.6 3.5 1.4 1 1 0 1 1 1 0 Spc7 kinetochore protein DivIVA PF05103.8 KKK23583.1 - 0.25 11.3 4.9 1.4 9.0 0.5 2.3 2 0 0 2 2 2 0 DivIVA protein CCDC-167 PF15188.1 KKK23583.1 - 0.41 10.6 10.8 1.3 8.9 4.3 2.4 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 V_ATPase_I PF01496.14 KKK23583.1 - 0.44 8.3 3.6 0.53 8.0 2.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Fez1 PF06818.10 KKK23583.1 - 0.58 10.1 11.1 0.15 12.1 2.9 2.1 1 1 0 2 2 2 0 Fez1 GAS PF13851.1 KKK23583.1 - 0.8 8.8 8.0 0.99 8.5 4.1 1.9 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF972 PF06156.8 KKK23583.1 - 0.86 9.9 4.5 17 5.8 0.7 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Nbl1_Borealin_N PF10444.4 KKK23583.1 - 1 8.7 5.4 4.7 6.6 0.9 2.7 1 1 1 2 2 2 0 Nbl1 / Borealin N terminal DUF4140 PF13600.1 KKK23583.1 - 1.1 9.7 8.9 5.2 7.5 0.8 2.7 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF4200 PF13863.1 KKK23583.1 - 3 7.8 10.7 9.3 6.2 3.3 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) DUF3552 PF12072.3 KKK23583.1 - 4.3 6.4 10.0 2.3 7.3 5.2 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3552) Spc24 PF08286.6 KKK23583.1 - 4.4 7.0 7.6 5.1 6.8 2.2 2.4 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 GrpE PF01025.14 KKK23583.1 - 5.2 6.5 8.5 3.4 7.1 0.2 2.2 1 1 0 2 2 2 0 GrpE TMF_DNA_bd PF12329.3 KKK23583.1 - 7.7 6.4 9.5 15 5.5 2.2 2.8 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding DOT1 PF08123.8 KKK23584.1 - 2.7e-77 258.7 0.0 3.7e-77 258.2 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_26 PF13659.1 KKK23584.1 - 0.00073 19.5 0.0 0.0016 18.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KKK23584.1 - 0.011 15.3 0.0 0.019 14.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 KKK23584.1 - 0.012 16.1 0.0 0.028 15.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain CMAS PF02353.15 KKK23584.1 - 0.17 10.9 0.0 0.33 10.0 0.0 1.4 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase FAM60A PF15396.1 KKK23584.1 - 2.4 7.8 5.3 4.9 6.8 3.6 1.5 1 0 0 1 1 1 0 Protein Family FAM60A Nucleo_P87 PF07267.6 KKK23584.1 - 5 5.6 6.2 8.9 4.8 4.3 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Spb1_C PF07780.7 KKK23585.1 - 2.1e-74 249.6 29.0 2.1e-74 249.6 20.1 2.9 3 1 0 3 3 3 1 Spb1 C-terminal domain FtsJ PF01728.14 KKK23585.1 - 4.4e-54 183.2 0.0 8.6e-54 182.2 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF3381 PF11861.3 KKK23585.1 - 5.2e-54 182.0 7.5 5.2e-54 182.0 5.2 4.5 4 1 0 4 4 4 1 Domain of unknown function (DUF3381) DUF2243 PF10002.4 KKK23586.1 - 0.2 11.4 0.0 0.39 10.4 0.0 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2243) Fungal_trans PF04082.13 KKK23587.1 - 2.7e-06 26.4 0.4 2.7e-06 26.4 0.3 1.9 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK23587.1 - 0.017 15.0 9.6 0.047 13.6 6.7 1.8 1 1 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain EF-hand_4 PF12763.2 KKK23588.1 - 1.5e-05 24.6 0.1 3.3e-05 23.5 0.1 1.5 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand Glyco_transf_15 PF01793.11 KKK23589.1 - 1.9e-132 441.2 2.5 2.3e-132 440.9 1.7 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase DUF4553 PF15090.1 KKK23589.1 - 0.21 10.5 0.0 0.3 10.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4553) PH PF00169.24 KKK23590.1 - 9.2e-26 90.0 0.4 3.6e-12 46.3 0.0 2.4 2 0 0 2 2 2 2 PH domain PH_11 PF15413.1 KKK23590.1 - 2.6e-12 46.9 1.0 5.6e-05 23.3 0.1 3.9 2 2 0 2 2 2 2 Pleckstrin homology domain PH_9 PF15410.1 KKK23590.1 - 1.8e-11 44.2 0.6 3.4e-06 27.1 0.1 4.0 2 2 0 2 2 2 2 Pleckstrin homology domain PH_8 PF15409.1 KKK23590.1 - 0.0014 18.6 0.1 0.1 12.7 0.0 2.3 2 0 0 2 2 2 1 Pleckstrin homology domain PH_6 PF15406.1 KKK23590.1 - 0.018 15.0 0.0 0.7 9.9 0.0 2.7 3 0 0 3 3 3 0 Pleckstrin homology domain ALG3 PF05208.8 KKK23591.1 - 2.3e-134 448.2 14.9 2.7e-134 448.0 10.3 1.0 1 0 0 1 1 1 1 ALG3 protein EpsG PF14897.1 KKK23591.1 - 0.00019 20.5 10.5 0.00025 20.0 7.0 1.6 1 1 0 1 1 1 1 EpsG family eIF-1a PF01176.14 KKK23592.1 - 2.2e-16 59.0 0.0 3.5e-16 58.3 0.0 1.3 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Peptidase_M20 PF01546.23 KKK23598.1 - 3e-11 43.1 0.8 4.7e-11 42.5 0.5 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 KKK23598.1 - 2.3e-05 24.1 0.0 3.4e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain MMR_HSR1 PF01926.18 KKK23599.1 - 1.4e-06 28.2 0.0 8.1e-06 25.7 0.0 2.3 2 1 0 2 2 2 1 50S ribosome-binding GTPase ATPase-cat_bd PF12156.3 KKK23599.1 - 0.00069 20.0 0.2 0.0019 18.6 0.1 1.7 1 0 0 1 1 1 1 Putative metal-binding domain of cation transport ATPase DUF258 PF03193.11 KKK23599.1 - 0.013 14.6 0.0 0.073 12.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Miro PF08477.8 KKK23599.1 - 0.03 14.8 0.0 0.091 13.2 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein Dynamin_N PF00350.18 KKK23599.1 - 0.031 14.0 0.1 3.4 7.4 0.1 2.8 1 1 1 2 2 2 0 Dynamin family tRNA-synt_1 PF00133.17 KKK23600.1 - 1.4e-37 128.9 0.0 5.8e-26 90.6 0.0 3.0 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 KKK23600.1 - 2.1e-18 66.1 0.0 2.1e-11 43.1 0.0 2.6 3 0 0 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.8 KKK23600.1 - 1.1e-14 54.4 0.2 2.7e-14 53.1 0.1 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 KKK23600.1 - 1.3e-07 31.0 0.0 3e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain S10_plectin PF03501.10 KKK23601.1 - 1.2e-41 140.5 0.1 1.5e-41 140.1 0.1 1.1 1 0 0 1 1 1 1 Plectin/S10 domain tRNA-synt_1c_C PF03950.13 KKK23601.1 - 0.033 13.8 0.0 0.04 13.5 0.0 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (E and Q), anti-codon binding domain Telomere_Sde2 PF13019.1 KKK23602.1 - 1.4e-65 219.9 0.3 2.2e-65 219.2 0.2 1.3 1 0 0 1 1 1 1 Telomere stability and silencing Rotamase_2 PF13145.1 KKK23602.1 - 0.0073 16.9 0.9 0.015 15.9 0.6 1.5 1 0 0 1 1 1 1 PPIC-type PPIASE domain RhoGEF PF00621.15 KKK23603.1 - 4.2e-32 111.4 0.8 7.1e-32 110.7 0.6 1.4 1 0 0 1 1 1 1 RhoGEF domain CDC24 PF06395.6 KKK23603.1 - 4e-31 106.9 0.0 1.2e-30 105.3 0.0 1.8 2 0 0 2 2 2 1 CDC24 Calponin PH_10 PF15411.1 KKK23603.1 - 0.097 12.8 0.0 0.21 11.7 0.0 1.6 1 0 0 1 1 1 0 Pleckstrin homology domain DUF4071 PF13281.1 KKK23603.1 - 0.11 11.2 1.1 1.9 7.2 0.0 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4071) FIVAR PF07554.8 KKK23603.1 - 0.16 12.2 0.7 0.88 9.8 0.1 2.3 2 0 0 2 2 2 0 Uncharacterised Sugar-binding Domain DUF4404 PF14357.1 KKK23603.1 - 0.18 12.2 4.3 0.87 10.0 0.3 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) WD40 PF00400.27 KKK23604.1 - 3.4e-44 147.1 9.4 5.5e-08 32.3 0.0 7.5 7 0 0 7 7 7 6 WD domain, G-beta repeat F-box-like PF12937.2 KKK23604.1 - 2.3e-13 49.6 0.4 5.6e-13 48.3 0.3 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KKK23604.1 - 5e-08 32.4 0.3 1.1e-07 31.2 0.2 1.7 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.3 KKK23604.1 - 0.00044 18.5 2.1 0.33 9.0 0.0 2.8 2 1 0 2 2 2 2 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 KKK23604.1 - 0.021 14.6 0.2 38 4.1 0.0 4.8 5 2 1 6 6 6 0 Ciliary BBSome complex subunit 2, middle region MFS_2 PF13347.1 KKK23605.1 - 1e-07 30.7 12.5 3.5e-07 28.9 4.2 2.4 2 0 0 2 2 2 2 MFS/sugar transport protein Na_H_Exchanger PF00999.16 KKK23607.1 - 1.1e-65 221.6 40.2 1.4e-65 221.3 27.9 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF1673 PF07895.6 KKK23607.1 - 1.5 8.3 0.0 1.5 8.3 0.0 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1673) AA_permease_2 PF13520.1 KKK23608.1 - 1.4e-56 191.8 42.9 1.9e-56 191.4 29.7 1.1 1 0 0 1 1 1 1 Amino acid permease MFS_1 PF07690.11 KKK23609.1 - 0.018 13.7 0.8 0.018 13.7 0.6 1.0 1 0 0 1 1 1 0 Major Facilitator Superfamily Yip1 PF04893.12 KKK23609.1 - 0.023 14.2 0.7 0.032 13.7 0.5 1.2 1 0 0 1 1 1 0 Yip1 domain AA_permease_2 PF13520.1 KKK23609.1 - 0.025 13.1 0.4 0.029 12.8 0.2 1.0 1 0 0 1 1 1 0 Amino acid permease MARVEL PF01284.18 KKK23609.1 - 0.042 13.6 1.4 0.052 13.3 1.0 1.2 1 0 0 1 1 1 0 Membrane-associating domain Col_cuticle_N PF01484.12 KKK23609.1 - 7.7 6.2 8.8 3.4 7.4 1.2 2.3 2 0 0 2 2 2 0 Nematode cuticle collagen N-terminal domain His_biosynth PF00977.16 KKK23610.1 - 8.3e-32 110.2 0.0 1e-31 110.0 0.0 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein Acetone_carb_G PF08882.6 KKK23610.1 - 0.096 12.7 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 Acetone carboxylase gamma subunit DUF4602 PF15375.1 KKK23611.1 - 1.2e-06 28.5 17.8 1.2e-06 28.5 12.3 2.8 1 1 1 2 2 2 1 Domain of unknown function (DUF4602) Daxx PF03344.10 KKK23611.1 - 0.26 9.7 24.8 0.32 9.4 17.2 1.1 1 0 0 1 1 1 0 Daxx Family SDA1 PF05285.7 KKK23611.1 - 0.43 9.8 25.1 0.75 9.0 17.4 1.4 1 0 0 1 1 1 0 SDA1 STE PF02200.11 KKK23612.1 - 5.7e-62 206.7 0.1 1.1e-61 205.8 0.1 1.5 1 0 0 1 1 1 1 STE like transcription factor zf-C2H2 PF00096.21 KKK23612.1 - 5.4e-12 45.3 9.4 1.1e-06 28.5 0.4 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KKK23612.1 - 1.1e-09 38.1 4.3 1.1e-09 38.1 3.0 3.2 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 KKK23612.1 - 1.1e-09 37.9 10.2 9.1e-05 22.5 0.7 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KKK23612.1 - 0.0067 16.3 0.4 0.019 14.8 0.0 1.9 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KKK23612.1 - 0.018 15.1 0.3 0.47 10.6 0.0 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-TRAF PF02176.13 KKK23612.1 - 0.035 14.5 2.3 0.059 13.7 1.6 1.4 1 0 0 1 1 1 0 TRAF-type zinc finger zf-RING_3 PF14369.1 KKK23612.1 - 0.053 13.5 0.2 0.14 12.2 0.1 1.7 1 0 0 1 1 1 0 zinc-finger zf-Di19 PF05605.7 KKK23612.1 - 0.71 10.0 3.2 1.8 8.7 2.2 1.7 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2HC_2 PF13913.1 KKK23612.1 - 1.1 8.9 4.9 1.9 8.2 0.2 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type NEP PF10167.4 KKK23613.1 - 0.04 13.6 0.1 0.081 12.6 0.1 1.4 1 0 0 1 1 1 0 Uncharacterised conserved protein YolD PF08863.5 KKK23613.1 - 0.063 13.1 0.4 0.16 11.8 0.3 1.7 1 0 0 1 1 1 0 YolD-like protein RFX_DNA_binding PF02257.10 KKK23614.1 - 1.8e-29 101.7 0.2 5.7e-29 100.0 0.1 1.9 1 0 0 1 1 1 1 RFX DNA-binding domain DUF2457 PF10446.4 KKK23615.1 - 0.0011 17.7 16.2 0.0011 17.7 11.3 2.5 2 1 1 3 3 3 1 Protein of unknown function (DUF2457) YL1 PF05764.8 KKK23615.1 - 0.0021 17.7 8.9 0.0021 17.7 6.1 2.1 2 0 0 2 2 2 1 YL1 nuclear protein SGT1 PF07093.6 KKK23615.1 - 0.021 13.2 8.1 0.031 12.6 5.6 1.3 1 0 0 1 1 1 0 SGT1 protein CDC45 PF02724.9 KKK23615.1 - 0.086 10.8 13.8 0.15 10.1 9.6 1.3 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 KKK23615.1 - 0.16 9.8 16.2 0.26 9.1 11.2 1.3 1 0 0 1 1 1 0 Nop14-like family Nop53 PF07767.6 KKK23615.1 - 0.72 8.7 10.5 0.034 13.1 1.7 2.2 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) Nucleoplasmin PF03066.10 KKK23615.1 - 1 8.8 18.0 1.8 8.0 12.5 1.3 1 0 0 1 1 1 0 Nucleoplasmin Sigma70_ner PF04546.8 KKK23615.1 - 1.8 8.1 17.3 0.14 11.7 7.9 2.0 2 0 0 2 2 2 0 Sigma-70, non-essential region NOA36 PF06524.7 KKK23615.1 - 4.8 6.3 20.6 11 5.2 14.3 1.5 1 0 0 1 1 1 0 NOA36 protein Tom22 PF04281.8 KKK23615.1 - 6.2 6.3 12.0 14 5.2 8.3 1.6 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 ThiF PF00899.16 KKK23616.1 - 1.2e-16 60.7 0.1 2.4e-16 59.8 0.0 1.5 2 0 0 2 2 2 1 ThiF family Ytp1 PF10355.4 KKK23617.1 - 4.1e-89 298.3 14.3 4.1e-89 298.3 9.9 1.9 2 0 0 2 2 2 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 KKK23617.1 - 3.9e-33 113.1 0.9 3.9e-33 113.1 0.6 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF2427) Swi5 PF07061.6 KKK23618.1 - 1.1e-30 105.2 0.7 1.1e-30 105.2 0.5 1.7 2 0 0 2 2 2 1 Swi5 DUF3373 PF11853.3 KKK23618.1 - 0.0055 15.2 0.2 0.007 14.9 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3373) Lzipper-MIP1 PF14389.1 KKK23618.1 - 0.049 13.7 0.1 0.095 12.8 0.1 1.5 1 0 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 Prefoldin_2 PF01920.15 KKK23618.1 - 0.08 12.7 1.8 0.21 11.3 1.1 1.8 1 1 1 2 2 2 0 Prefoldin subunit STIL_N PF15253.1 KKK23618.1 - 0.2 10.3 4.9 0.26 9.9 3.4 1.1 1 0 0 1 1 1 0 SCL-interrupting locus protein N-terminus DUF4094 PF13334.1 KKK23618.1 - 0.97 9.8 3.2 1.6 9.1 2.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) XhlA PF10779.4 KKK23618.1 - 2.8 7.9 7.1 7.8 6.4 4.7 2.0 1 1 0 1 1 1 0 Haemolysin XhlA ABC_tran PF00005.22 KKK23619.1 - 2e-12 47.5 0.0 3.6e-12 46.7 0.0 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.14 KKK23619.1 - 0.00014 21.1 0.1 0.00018 20.7 0.0 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.1 KKK23619.1 - 0.0043 16.9 1.1 0.056 13.3 0.8 2.3 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit DUF4066 PF13278.1 KKK23619.1 - 0.068 12.4 0.0 0.075 12.3 0.0 1.2 1 0 0 1 1 1 0 Putative amidotransferase AAA_21 PF13304.1 KKK23619.1 - 0.097 12.6 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain Radical_SAM PF04055.16 KKK23620.1 - 1.2e-18 67.8 0.1 3.4e-18 66.3 0.0 1.8 2 0 0 2 2 2 1 Radical SAM superfamily Acetyltransf_1 PF00583.19 KKK23620.1 - 3.7e-12 46.1 0.0 9.5e-12 44.7 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 KKK23620.1 - 0.058 13.5 0.0 0.14 12.2 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain CoA_binding PF02629.14 KKK23621.1 - 3.8e-26 91.4 3.8 2.7e-25 88.6 1.0 2.3 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.14 KKK23621.1 - 3.4e-23 81.9 0.2 5.6e-23 81.2 0.2 1.4 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.1 KKK23621.1 - 6.3e-07 29.0 0.0 1.2e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 KKK23621.1 - 0.0021 18.2 0.1 0.005 16.9 0.1 1.7 1 0 0 1 1 1 1 CoA binding domain FBPase_glpX PF03320.8 KKK23621.1 - 0.053 12.1 0.0 4.3 5.8 0.0 2.1 2 0 0 2 2 2 0 Bacterial fructose-1,6-bisphosphatase, glpX-encoded Aldedh PF00171.17 KKK23623.1 - 1.1e-133 446.0 0.3 1.3e-133 445.7 0.2 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 KKK23623.1 - 0.039 12.6 0.0 0.067 11.9 0.0 1.3 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) Yos1 PF08571.5 KKK23624.1 - 4.4e-05 23.4 0.0 6.5e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Yos1-like UCH PF00443.24 KKK23625.1 - 6e-65 219.0 0.1 1.1e-64 218.1 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KKK23625.1 - 1.7e-30 106.5 1.0 1.4e-22 80.4 0.0 2.4 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.1 KKK23625.1 - 0.0087 15.3 3.6 0.046 13.0 1.2 2.5 2 0 0 2 2 2 1 Ubiquitin-specific peptidase-like, SUMO isopeptidase DUF2252 PF10009.4 KKK23625.1 - 0.4 9.5 5.7 0.77 8.5 4.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) Dynamitin PF04912.9 KKK23626.1 - 1.5e-34 119.5 10.0 6.9e-18 64.6 1.8 2.2 2 0 0 2 2 2 2 Dynamitin DUF241 PF03087.9 KKK23626.1 - 0.0062 16.0 5.4 0.11 11.9 0.4 2.3 2 0 0 2 2 2 2 Arabidopsis protein of unknown function Laminin_II PF06009.7 KKK23626.1 - 0.013 15.2 0.1 0.013 15.2 0.1 3.8 4 2 1 5 5 5 0 Laminin Domain II IncA PF04156.9 KKK23626.1 - 0.051 13.1 23.1 0.033 13.7 6.9 2.7 2 1 0 2 2 2 0 IncA protein CorA PF01544.13 KKK23626.1 - 0.25 10.3 8.2 0.053 12.5 2.0 2.1 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein STAT_alpha PF01017.15 KKK23626.1 - 0.51 10.0 7.4 0.098 12.3 0.6 2.5 3 0 0 3 3 3 0 STAT protein, all-alpha domain Prefoldin_2 PF01920.15 KKK23626.1 - 0.86 9.3 14.5 0.24 11.1 0.6 3.7 3 2 0 3 3 3 0 Prefoldin subunit DUF342 PF03961.8 KKK23626.1 - 0.89 7.8 8.3 1.7 6.9 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF342) TBPIP PF07106.8 KKK23626.1 - 1.7 8.2 11.3 0.55 9.7 1.8 2.9 2 1 1 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DMPK_coil PF08826.5 KKK23626.1 - 2.2 8.2 12.5 2.6 7.9 0.1 3.6 2 1 1 3 3 3 0 DMPK coiled coil domain like EMP24_GP25L PF01105.19 KKK23626.1 - 2.2 7.9 5.6 0.69 9.5 0.8 2.3 2 1 0 2 2 2 0 emp24/gp25L/p24 family/GOLD Prefoldin PF02996.12 KKK23626.1 - 2.7 7.6 14.1 5.5 6.6 0.0 4.6 3 2 3 6 6 6 0 Prefoldin subunit DivIC PF04977.10 KKK23626.1 - 3.9 7.0 14.8 0.35 10.3 0.1 3.5 4 0 0 4 4 4 0 Septum formation initiator Syntaxin-6_N PF09177.6 KKK23626.1 - 4.9 7.6 16.0 9.1 6.7 2.3 4.1 2 2 3 5 5 5 0 Syntaxin 6, N-terminal GvpK PF05121.7 KKK23626.1 - 7.4 6.4 8.4 1.8 8.4 2.0 2.8 2 1 0 2 2 2 0 Gas vesicle protein K Glyco_transf_22 PF03901.12 KKK23627.1 - 1.2e-37 129.9 13.9 1.5e-37 129.6 9.7 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family DUF3267 PF11667.3 KKK23627.1 - 0.0053 16.9 3.2 0.012 15.8 1.3 2.3 1 1 1 2 2 2 1 Protein of unknown function (DUF3267) HupE_UreJ_2 PF13795.1 KKK23627.1 - 0.07 12.6 1.3 0.79 9.1 0.2 2.4 1 1 1 2 2 2 0 HupE / UreJ protein PX PF00787.19 KKK23628.1 - 5.1e-19 68.1 0.4 1.2e-18 66.9 0.3 1.6 1 0 0 1 1 1 1 PX domain Vps5 PF09325.5 KKK23628.1 - 5.4e-15 55.2 6.7 2.7e-07 30.0 0.2 2.1 2 0 0 2 2 2 2 Vps5 C terminal like BAR PF03114.13 KKK23628.1 - 0.00074 19.0 4.1 0.0027 17.2 2.9 2.0 1 1 0 1 1 1 1 BAR domain DUF3140 PF11338.3 KKK23628.1 - 0.023 14.8 0.3 0.1 12.7 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3140) DUF724 PF05266.9 KKK23628.1 - 0.1 12.2 3.2 6.5 6.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF724) FlaC_arch PF05377.6 KKK23628.1 - 0.2 11.6 1.6 15 5.5 0.0 2.7 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Laminin_II PF06009.7 KKK23628.1 - 0.22 11.2 2.6 0.31 10.7 0.2 2.3 2 1 1 3 3 3 0 Laminin Domain II IncA PF04156.9 KKK23628.1 - 0.36 10.4 1.7 3.4 7.2 0.0 2.1 2 0 0 2 2 2 0 IncA protein Prefoldin_2 PF01920.15 KKK23628.1 - 0.55 10.0 3.5 2.2 8.0 0.1 2.4 2 0 0 2 2 2 0 Prefoldin subunit DUF1664 PF07889.7 KKK23628.1 - 1 9.1 4.4 5.8 6.7 0.2 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Peptidase_S8 PF00082.17 KKK23629.1 - 1.7e-52 178.3 1.1 2.6e-52 177.7 0.7 1.3 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.15 KKK23629.1 - 5.8e-29 99.7 1.4 1.1e-28 98.8 1.0 1.5 1 0 0 1 1 1 1 Proprotein convertase P-domain FAD_binding_3 PF01494.14 KKK23630.1 - 3.7e-18 65.7 1.7 2.9e-15 56.1 1.2 3.0 1 1 0 1 1 1 1 FAD binding domain SE PF08491.5 KKK23630.1 - 1.7e-06 27.0 0.0 3.3e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Squalene epoxidase Lycopene_cycl PF05834.7 KKK23630.1 - 0.00045 19.2 0.1 0.0018 17.2 0.0 1.9 2 0 0 2 2 2 1 Lycopene cyclase protein DAO PF01266.19 KKK23630.1 - 0.00079 18.4 0.0 0.051 12.4 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KKK23630.1 - 0.00081 19.1 0.0 0.002 17.9 0.0 1.7 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 KKK23630.1 - 0.021 14.7 0.0 0.034 14.0 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KKK23630.1 - 0.036 12.9 0.0 0.059 12.2 0.0 1.3 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 KKK23630.1 - 0.045 13.7 0.0 0.12 12.4 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 KKK23630.1 - 0.067 13.2 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KKK23630.1 - 0.068 11.6 0.1 0.12 10.8 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein DUF3115 PF11312.3 KKK23630.1 - 0.13 11.0 0.0 0.19 10.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3115) Thi4 PF01946.12 KKK23630.1 - 0.18 10.8 0.0 0.29 10.1 0.0 1.2 1 0 0 1 1 1 0 Thi4 family Period_C PF12114.3 KKK23631.1 - 2.1 7.9 6.5 2.3 7.7 4.5 1.1 1 0 0 1 1 1 0 Period protein 2/3C-terminal region LSM PF01423.17 KKK23644.1 - 3.2e-13 49.0 1.4 1.1e-12 47.3 0.9 1.8 1 1 0 1 1 1 1 LSM domain SH3_9 PF14604.1 KKK23644.1 - 0.46 10.1 2.2 6.3 6.4 0.0 2.8 3 1 0 3 3 3 0 Variant SH3 domain ATP13 PF12921.2 KKK23645.1 - 1.2e-25 89.3 0.0 2.1e-25 88.4 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial ATPase expression PPR_2 PF13041.1 KKK23645.1 - 0.0037 17.2 0.0 0.79 9.7 0.0 3.0 2 0 0 2 2 2 1 PPR repeat family PPR_3 PF13812.1 KKK23645.1 - 0.019 15.2 1.0 28 5.3 0.0 4.4 5 0 0 5 5 5 0 Pentatricopeptide repeat domain GTP_EFTU PF00009.22 KKK23646.1 - 9.5e-22 77.3 0.1 4.4e-21 75.1 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 KKK23646.1 - 2.3e-14 53.3 0.0 4.8e-14 52.3 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 KKK23646.1 - 2.3e-06 27.6 0.9 8.9e-06 25.7 0.7 2.1 1 0 0 1 1 1 1 Elongation factor Tu domain 2 PduV-EutP PF10662.4 KKK23646.1 - 0.0011 18.4 0.7 0.18 11.2 0.1 3.2 2 1 1 3 3 3 1 Ethanolamine utilisation - propanediol utilisation Miro PF08477.8 KKK23646.1 - 0.032 14.7 0.4 0.95 9.9 0.3 3.0 2 1 0 2 2 2 0 Miro-like protein MMR_HSR1 PF01926.18 KKK23646.1 - 0.072 13.0 0.0 0.21 11.5 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase tRNA-synt_His PF13393.1 KKK23647.1 - 2.8e-45 154.7 0.0 1.3e-38 132.7 0.0 2.0 2 0 0 2 2 2 2 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.20 KKK23647.1 - 2.2e-18 66.4 0.0 3.6e-18 65.7 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 KKK23647.1 - 2.9e-11 43.1 0.0 5.7e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2 PF00152.15 KKK23647.1 - 9.4e-05 21.3 0.0 0.0088 14.8 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II (D, K and N) Transp_cyt_pur PF02133.10 KKK23654.1 - 4.5e-21 74.9 36.5 7.1e-21 74.2 25.3 1.2 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin COX5B PF01215.14 KKK23655.1 - 1.1e-35 122.2 0.0 1.8e-35 121.5 0.0 1.3 1 1 0 1 1 1 1 Cytochrome c oxidase subunit Vb Myb_DNA-binding PF00249.26 KKK23656.1 - 3.3e-12 46.2 5.4 6.2e-07 29.3 2.0 3.0 2 1 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KKK23656.1 - 1.2e-10 41.3 3.5 2.7e-06 27.4 0.4 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain DIRP PF06584.8 KKK23656.1 - 0.17 11.7 0.8 1 9.2 0.0 2.4 2 1 1 3 3 3 0 DIRP Ribosomal_L34e PF01199.13 KKK23657.1 - 4.6e-38 129.3 2.9 6.1e-38 128.9 2.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L34e Myb_DNA-bind_6 PF13921.1 KKK23658.1 - 1.4e-13 50.6 0.0 4.4e-08 33.1 0.0 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 KKK23658.1 - 1.3e-10 41.1 0.1 2.6e-05 24.1 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain PROCN PF08083.6 KKK23659.1 - 8.7e-224 742.4 8.3 1.5e-223 741.6 5.7 1.4 1 0 0 1 1 1 1 PROCN (NUC071) domain PRP8_domainIV PF12134.3 KKK23659.1 - 1.4e-124 413.8 1.5 2.5e-124 413.1 1.0 1.4 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.4 KKK23659.1 - 1.6e-101 336.3 0.1 3.1e-62 208.6 0.1 2.6 2 0 0 2 2 2 2 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.6 KKK23659.1 - 2.5e-77 257.7 3.1 4.2e-77 256.9 1.3 2.1 2 0 0 2 2 2 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.4 KKK23659.1 - 1.9e-67 225.0 0.1 5.3e-67 223.5 0.1 1.8 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 Hom_end_hint PF05203.11 KKK23659.1 - 1.3e-52 178.6 6.8 1.5e-31 109.7 0.0 3.3 2 1 1 3 3 3 2 Hom_end-associated Hint PROCT PF08084.6 KKK23659.1 - 3.5e-45 152.7 0.0 9.4e-45 151.3 0.0 1.8 1 0 0 1 1 1 1 PROCT (NUC072) domain RRM_4 PF10598.4 KKK23659.1 - 1.1e-44 150.1 0.2 3.2e-44 148.7 0.1 1.9 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 Hint_2 PF13403.1 KKK23659.1 - 0.0094 15.8 0.0 0.041 13.8 0.0 2.0 1 1 0 1 1 1 1 Hint domain OCD_Mu_crystall PF02423.10 KKK23659.1 - 0.082 11.6 1.0 0.15 10.7 0.7 1.3 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family DUF3753 PF12575.3 KKK23659.1 - 0.092 12.5 0.0 0.27 11.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) FTR1 PF03239.9 KKK23676.1 - 1.4e-92 309.9 1.5 1.6e-92 309.7 1.1 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family DUF1467 PF07330.7 KKK23676.1 - 0.036 13.8 3.9 0.96 9.2 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1467) DUF4282 PF14110.1 KKK23676.1 - 0.04 14.0 1.7 0.04 14.0 1.2 3.4 3 1 0 3 3 3 0 Domain of unknown function (DUF4282) Wzy_C PF04932.10 KKK23676.1 - 0.29 10.8 7.0 12 5.6 4.8 2.6 1 1 0 1 1 1 0 O-Antigen ligase Tmemb_14 PF03647.8 KKK23676.1 - 0.68 10.3 8.8 4.5 7.7 0.1 3.4 3 0 0 3 3 3 0 Transmembrane proteins 14C Cu-oxidase_2 PF07731.9 KKK23677.1 - 6.9e-40 135.7 8.8 9.7e-39 132.0 0.5 3.7 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 KKK23677.1 - 9.6e-40 134.9 11.1 1.8e-38 130.9 1.2 3.7 4 0 0 4 4 4 2 Multicopper oxidase Cu-oxidase PF00394.17 KKK23677.1 - 1.4e-36 125.7 6.3 1.1e-35 122.8 0.4 3.4 3 1 0 3 3 3 1 Multicopper oxidase Abhydrolase_3 PF07859.8 KKK23678.1 - 1.3e-66 224.1 0.1 1.8e-66 223.7 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 KKK23678.1 - 4.3e-08 32.3 0.0 7.6e-08 31.5 0.0 1.3 1 0 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.16 KKK23678.1 - 2.1e-07 30.3 0.0 3.7e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family DUF2424 PF10340.4 KKK23678.1 - 0.0045 15.6 0.0 0.014 14.0 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2424) PhzC-PhzF PF02567.11 KKK23678.1 - 0.037 13.2 0.0 0.064 12.4 0.0 1.3 1 0 0 1 1 1 0 Phenazine biosynthesis-like protein PhoD PF09423.5 KKK23679.1 - 6.6e-60 202.9 0.0 9.4e-60 202.4 0.0 1.1 1 0 0 1 1 1 1 PhoD-like phosphatase Glyco_hydro_18 PF00704.23 KKK23679.1 - 8e-06 25.5 0.0 1.8e-05 24.3 0.0 1.5 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 ATG16 PF08614.6 KKK23680.1 - 0.0001 22.2 19.7 0.0001 22.2 13.6 4.7 1 1 2 4 4 4 1 Autophagy protein 16 (ATG16) Fib_alpha PF08702.5 KKK23680.1 - 0.0047 17.0 12.0 0.0047 17.0 8.3 6.0 3 2 2 6 6 6 3 Fibrinogen alpha/beta chain family Cep57_CLD_2 PF14197.1 KKK23680.1 - 0.032 14.1 0.3 0.032 14.1 0.2 7.9 7 2 3 10 10 10 0 Centrosome localisation domain of PPC89 LSM PF01423.17 KKK23682.1 - 1.3e-12 47.0 0.1 1.7e-12 46.7 0.1 1.2 1 0 0 1 1 1 1 LSM domain FtsL PF04999.8 KKK23683.1 - 2.8 7.7 4.9 1.2 8.9 1.2 1.9 1 1 1 2 2 2 0 Cell division protein FtsL Sugar_tr PF00083.19 KKK23684.1 - 5.1e-127 424.1 24.9 5.9e-127 423.9 17.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KKK23684.1 - 4.3e-24 84.8 55.0 3.6e-21 75.2 19.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MSP1b PF03429.8 KKK23684.1 - 0.11 10.4 0.3 0.15 9.8 0.2 1.1 1 0 0 1 1 1 0 Major surface protein 1B Cation_efflux PF01545.16 KKK23685.1 - 3.8e-83 278.8 0.1 6.9e-83 277.9 0.0 1.4 1 1 0 1 1 1 1 Cation efflux family Zip PF02535.17 KKK23685.1 - 0.00012 21.2 1.1 0.00016 20.8 0.1 1.6 2 0 0 2 2 2 1 ZIP Zinc transporter MFS_1 PF07690.11 KKK23686.1 - 2.8e-33 115.0 41.6 2.8e-33 115.0 28.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily HATPase_c PF02518.21 KKK23687.1 - 5.6e-30 103.3 0.0 1.4e-29 101.9 0.0 1.7 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 KKK23687.1 - 1.4e-24 86.2 1.3 2.5e-24 85.4 0.3 1.9 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.20 KKK23687.1 - 5.3e-14 51.9 0.0 1.6e-13 50.3 0.0 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.20 KKK23687.1 - 0.00023 21.2 1.2 0.00023 21.2 0.8 3.0 2 1 0 2 2 2 1 HAMP domain Abhydro_lipase PF04083.11 KKK23688.1 - 6.4e-22 76.6 0.6 1.5e-21 75.5 0.0 2.0 2 0 0 2 2 2 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_6 PF12697.2 KKK23688.1 - 1.6e-08 34.7 3.1 1.7e-08 34.6 1.4 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KKK23688.1 - 3.3e-05 23.6 0.0 7.3e-05 22.5 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KKK23688.1 - 0.0026 17.3 0.1 0.0056 16.2 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Metallophos PF00149.23 KKK23689.1 - 8.5e-06 25.3 1.7 0.0004 19.8 1.0 3.0 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase Glyco_hydro_61 PF03443.9 KKK23691.1 - 2.9e-63 213.5 0.0 2.9e-63 213.5 0.0 2.0 2 1 1 3 3 3 1 Glycosyl hydrolase family 61 CBM_1 PF00734.13 KKK23691.1 - 7.3e-13 47.9 5.8 1.9e-12 46.6 4.0 1.8 1 0 0 1 1 1 1 Fungal cellulose binding domain Dfp1_Him1_M PF08630.5 KKK23692.1 - 1.5e-40 137.8 0.0 3.3e-40 136.7 0.0 1.6 1 0 0 1 1 1 1 Dfp1/Him1, central region zf-DBF PF07535.7 KKK23692.1 - 7.5e-25 86.3 0.3 1.6e-24 85.2 0.2 1.6 1 0 0 1 1 1 1 DBF zinc finger BRCT PF00533.21 KKK23692.1 - 0.12 12.5 0.0 0.22 11.7 0.0 1.4 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain Pyridox_ox_2 PF12900.2 KKK23693.1 - 9.3e-39 132.5 0.0 1.2e-38 132.1 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Peptidase_M24 PF00557.19 KKK23694.1 - 1.1e-44 152.5 0.0 1.8e-44 151.8 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 KKK23694.1 - 9.6e-36 122.1 0.0 1.7e-35 121.2 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Creatinase_N PF01321.13 KKK23694.1 - 0.043 14.3 0.0 0.12 12.9 0.0 1.8 1 1 0 1 1 1 0 Creatinase/Prolidase N-terminal domain 4HBT PF03061.17 KKK23695.1 - 1.1e-08 35.1 0.0 1.9e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 Thioesterase superfamily SIR2 PF02146.12 KKK23696.1 - 1.6e-39 135.4 0.0 4.3e-39 134.0 0.0 1.6 1 1 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.17 KKK23696.1 - 0.023 14.4 0.0 0.21 11.3 0.0 2.1 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain AgrD PF05931.6 KKK23696.1 - 0.13 11.9 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 Staphylococcal AgrD protein Fungal_trans PF04082.13 KKK23703.1 - 3.2e-30 104.8 0.6 6.3e-30 103.9 0.4 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF2420 PF10336.4 KKK23705.1 - 5.9e-11 41.9 0.7 1e-10 41.1 0.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2420) DUF4661 PF15576.1 KKK23705.1 - 5.7 6.4 7.3 20 4.7 5.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) Adap_comp_sub PF00928.16 KKK23706.1 - 1.3e-17 63.7 0.0 2.2e-17 63.0 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 KKK23706.1 - 5.6e-06 26.1 0.1 9.7e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain RPM2 PF08579.6 KKK23706.1 - 0.0034 17.4 0.2 0.0072 16.4 0.1 1.5 1 0 0 1 1 1 1 Mitochondrial ribonuclease P subunit (RPM2) TMF_DNA_bd PF12329.3 KKK23707.1 - 0.036 13.8 3.5 0.071 12.9 2.4 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Spc7 PF08317.6 KKK23707.1 - 0.3 9.7 2.9 0.48 9.0 2.0 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein OMPdecase PF00215.19 KKK23708.1 - 4.5e-10 39.3 0.0 9e-07 28.5 0.0 2.4 2 1 0 2 2 2 2 Orotidine 5'-phosphate decarboxylase / HUMPS family RRM_1 PF00076.17 KKK23709.1 - 1e-40 137.1 0.8 2.8e-19 68.5 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KKK23709.1 - 6.4e-31 106.1 0.1 4e-17 61.9 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.1 KKK23709.1 - 2.1e-29 101.5 0.2 4.6e-29 100.4 0.1 1.6 1 0 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_5 PF13893.1 KKK23709.1 - 1.3e-19 69.7 0.0 4.7e-08 32.7 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cyt-b5 PF00173.23 KKK23709.1 - 7e-19 67.4 0.2 2.5e-18 65.6 0.0 2.0 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.8 KKK23709.1 - 1.3e-08 35.1 20.0 3e-08 34.0 13.6 1.7 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily RRM_3 PF08777.6 KKK23709.1 - 0.015 15.1 0.0 0.048 13.5 0.0 1.8 1 0 0 1 1 1 0 RNA binding motif COX14 PF14880.1 KKK23709.1 - 0.35 10.5 2.2 0.49 10.0 0.4 2.0 2 0 0 2 2 2 0 Cytochrome oxidase c assembly MIP-T3 PF10243.4 KKK23709.1 - 4.8 5.5 21.4 7.7 4.8 14.8 1.3 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Mg_trans_NIPA PF05653.9 KKK23710.1 - 1.1e-93 313.5 14.5 5.1e-90 301.4 7.1 2.0 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.15 KKK23710.1 - 1.7e-05 24.8 4.6 1.7e-05 24.8 3.2 3.3 3 1 0 3 3 3 1 EamA-like transporter family EmrE PF13536.1 KKK23710.1 - 3.4e-05 23.9 4.2 3.4e-05 23.9 2.9 3.6 2 1 0 3 3 3 1 Multidrug resistance efflux transporter DUF2937 PF11157.3 KKK23710.1 - 0.0057 15.9 1.1 0.011 15.1 0.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2937) CDC73 PF05179.9 KKK23722.1 - 9.3e-41 139.9 0.2 8.6e-40 136.8 0.1 2.5 1 1 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family RGS PF00615.14 KKK23723.1 - 1e-19 70.7 0.0 1.2e-19 70.5 0.0 1.1 1 0 0 1 1 1 1 Regulator of G protein signaling domain Glyco_hydro_61 PF03443.9 KKK23725.1 - 4.5e-78 262.0 0.0 5.2e-78 261.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 SET PF00856.23 KKK23726.1 - 8.1e-06 26.2 3.0 3.6e-05 24.1 0.1 3.1 3 1 0 3 3 3 1 SET domain PHD PF00628.24 KKK23726.1 - 1.6e-05 24.4 10.0 3.1e-05 23.5 6.9 1.5 1 0 0 1 1 1 1 PHD-finger RasGEF PF00617.14 KKK23733.1 - 0.02 14.6 0.0 0.26 10.9 0.0 2.5 2 1 1 3 3 3 0 RasGEF domain Adeno_E3_CR2 PF02439.10 KKK23740.1 - 0.27 10.8 1.0 0.49 9.9 0.7 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF1992 PF09350.5 KKK23741.1 - 8.7e-25 86.3 1.1 1.5e-24 85.5 0.2 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1992) NPP1 PF05630.6 KKK23767.1 - 1.5e-55 188.1 0.0 1.7e-55 187.9 0.0 1.0 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) SurE PF01975.12 KKK23768.1 - 2.3e-33 115.1 1.5 3.3e-33 114.6 1.0 1.2 1 0 0 1 1 1 1 Survival protein SurE Glyco_hydro_61 PF03443.9 KKK23769.1 - 3.2e-85 285.3 0.4 3.2e-85 285.3 0.3 1.9 2 0 0 2 2 2 1 Glycosyl hydrolase family 61 CBM_1 PF00734.13 KKK23769.1 - 5.5e-12 45.1 4.7 5.5e-12 45.1 3.3 1.9 2 0 0 2 2 2 1 Fungal cellulose binding domain RPE65 PF03055.10 KKK23770.1 - 7.1e-105 351.3 0.0 9.9e-105 350.8 0.0 1.2 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein adh_short PF00106.20 KKK23797.1 - 1.3e-19 70.7 0.0 1.6e-19 70.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KKK23797.1 - 6.7e-16 58.7 0.0 8.1e-16 58.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KKK23797.1 - 1.6e-06 27.9 0.0 2.2e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KKK23797.1 - 1.7e-05 24.9 0.1 2.1e-05 24.6 0.1 1.4 1 1 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 KKK23797.1 - 0.0002 20.4 0.1 0.00029 19.9 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Shikimate_DH PF01488.15 KKK23797.1 - 0.0014 18.7 0.0 0.0032 17.5 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.16 KKK23797.1 - 0.0027 17.1 0.1 0.0057 16.1 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_2 PF03446.10 KKK23797.1 - 0.0031 17.3 0.0 0.0059 16.4 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 KKK23797.1 - 0.013 15.8 0.1 0.032 14.6 0.0 1.7 2 0 0 2 2 1 0 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.11 KKK23797.1 - 0.02 14.3 0.0 0.035 13.5 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DNA_pol_viral_C PF00336.13 KKK23797.1 - 0.037 13.2 0.0 0.053 12.7 0.0 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) C-terminal domain NmrA PF05368.8 KKK23797.1 - 0.06 12.5 0.1 0.088 12.0 0.1 1.2 1 0 0 1 1 1 0 NmrA-like family ADH_zinc_N PF00107.21 KKK23797.1 - 0.063 12.8 0.1 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 Zinc-binding dehydrogenase THF_DHG_CYH_C PF02882.14 KKK23797.1 - 0.14 11.2 0.0 0.27 10.3 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Syja_N PF02383.13 KKK23798.1 - 4.3e-92 308.2 0.0 5.4e-92 307.9 0.0 1.1 1 0 0 1 1 1 1 SacI homology domain cobW PF02492.14 KKK23801.1 - 3.7e-39 133.9 0.0 5.2e-39 133.5 0.0 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain Zip PF02535.17 KKK23801.1 - 0.0049 15.9 0.7 0.0055 15.7 0.5 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter MobB PF03205.9 KKK23801.1 - 0.0057 16.3 0.0 0.012 15.3 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B CobW_C PF07683.9 KKK23801.1 - 0.012 15.3 0.0 0.18 11.5 0.0 2.7 1 1 1 2 2 2 0 Cobalamin synthesis protein cobW C-terminal domain AAA_19 PF13245.1 KKK23801.1 - 0.013 15.2 0.0 0.036 13.8 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_22 PF13401.1 KKK23801.1 - 0.022 14.9 0.7 0.097 12.8 0.0 2.2 3 0 0 3 3 3 0 AAA domain AAA_29 PF13555.1 KKK23801.1 - 0.033 13.7 0.0 0.6 9.6 0.0 2.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_14 PF13173.1 KKK23801.1 - 0.046 13.6 0.0 0.1 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 KKK23801.1 - 0.063 13.5 0.3 0.17 12.2 0.2 1.8 1 1 0 1 1 1 0 AAA domain SelP_N PF04592.9 KKK23801.1 - 0.077 12.3 7.7 0.12 11.7 5.3 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region BAF1_ABF1 PF04684.8 KKK23801.1 - 1.7 7.4 10.9 2.3 6.9 7.6 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Orn_Arg_deC_N PF02784.11 KKK23802.1 - 1e-76 257.4 0.0 1.4e-76 256.9 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 KKK23802.1 - 6.1e-31 106.5 0.0 1.3e-30 105.5 0.0 1.5 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Mitofilin PF09731.4 KKK23804.1 - 2.1e-158 528.5 11.2 3.4e-158 527.9 7.8 1.3 1 0 0 1 1 1 1 Mitochondrial inner membrane protein Pex14_N PF04695.8 KKK23804.1 - 0.12 12.4 0.1 0.12 12.4 0.0 3.1 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Ras PF00071.17 KKK23805.1 - 2.3e-47 160.3 0.5 2.9e-47 160.0 0.3 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KKK23805.1 - 9.7e-12 45.4 0.1 1.8e-11 44.5 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KKK23805.1 - 1.3e-10 40.7 0.1 1.6e-10 40.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KKK23805.1 - 3.5e-08 33.0 0.0 4.4e-08 32.7 0.0 1.0 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 KKK23805.1 - 3.8e-05 22.9 0.0 4.6e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region CTP_transf_3 PF02348.14 KKK23805.1 - 0.034 13.7 0.2 0.1 12.2 0.1 1.6 1 1 1 2 2 2 0 Cytidylyltransferase Shikimate_DH PF01488.15 KKK23805.1 - 0.11 12.6 0.0 0.4 10.7 0.0 1.8 1 1 1 2 2 2 0 Shikimate / quinate 5-dehydrogenase AAT PF03417.11 KKK23805.1 - 0.14 11.5 0.1 0.21 11.0 0.1 1.2 1 0 0 1 1 1 0 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase tRNA-synt_1g PF09334.6 KKK23806.1 - 1.1e-111 373.3 0.0 2.1e-111 372.3 0.0 1.5 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 KKK23806.1 - 4.9e-23 80.9 0.1 1.2e-10 40.1 0.0 3.7 1 1 3 4 4 4 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.14 KKK23806.1 - 5.6e-11 42.1 0.0 0.00025 20.2 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Anticodon_1 PF08264.8 KKK23806.1 - 0.001 18.8 0.0 0.0021 17.8 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA HTH_AraC PF00165.18 KKK23806.1 - 0.1 12.4 0.1 1.4 8.8 0.0 2.5 1 1 1 2 2 2 0 Bacterial regulatory helix-turn-helix proteins, AraC family NTF2 PF02136.15 KKK23807.1 - 2.8e-07 30.9 0.8 6e-07 29.8 0.6 1.5 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Mtr2 PF10429.4 KKK23807.1 - 0.0004 20.1 0.1 0.0017 18.1 0.1 1.8 2 0 0 2 2 2 1 Nuclear pore RNA shuttling protein Mtr2 PPTA PF01239.17 KKK23808.1 - 2.2e-38 127.9 20.7 2.6e-09 36.0 0.5 5.7 6 0 0 6 6 6 5 Protein prenyltransferase alpha subunit repeat TPR_19 PF14559.1 KKK23808.1 - 0.00062 20.0 0.3 0.0071 16.6 0.0 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 KKK23808.1 - 0.027 15.1 0.0 0.42 11.3 0.0 2.7 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 KKK23808.1 - 0.047 14.3 0.2 1 10.2 0.0 3.1 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.1 KKK23808.1 - 0.22 11.1 2.1 0.61 9.7 0.4 2.5 3 0 0 3 3 3 0 TPR repeat PALP PF00291.20 KKK23809.1 - 1.9e-48 165.3 1.2 3.1e-48 164.5 0.3 1.7 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme Pex26 PF07163.7 KKK23809.1 - 0.12 11.3 0.5 0.19 10.6 0.4 1.2 1 0 0 1 1 1 0 Pex26 protein DUF3446 PF11928.3 KKK23809.1 - 1.9 8.7 16.7 0.033 14.3 2.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF3446) GHMP_kinases_N PF00288.21 KKK23810.1 - 2.4e-19 69.1 0.1 8.4e-19 67.4 0.1 2.0 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 KKK23810.1 - 5.5e-07 29.7 0.0 1.4e-06 28.3 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.4 KKK23810.1 - 0.0048 16.1 0.0 0.011 15.0 0.0 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature Fungal_trans_2 PF11951.3 KKK23811.1 - 1.2e-28 99.8 0.1 5.9e-18 64.6 0.0 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK23811.1 - 3.9e-09 36.2 7.9 6.8e-09 35.5 5.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Alpha-amylase PF00128.19 KKK23812.1 - 8.8e-29 100.8 0.0 1.5e-28 100.0 0.0 1.3 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_hydro_70 PF02324.11 KKK23812.1 - 3.6e-07 28.3 0.0 0.004 14.9 0.0 3.0 3 0 0 3 3 3 3 Glycosyl hydrolase family 70 GPI-anchored PF10342.4 KKK23813.1 - 5e-21 74.9 2.4 5e-21 74.9 1.7 2.6 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Mucin PF01456.12 KKK23813.1 - 0.33 10.7 34.4 0.11 12.3 21.7 1.7 2 0 0 2 2 2 0 Mucin-like glycoprotein Macoilin PF09726.4 KKK23813.1 - 0.38 8.9 17.9 0.41 8.8 12.4 1.0 1 0 0 1 1 1 0 Transmembrane protein CCDC84 PF14968.1 KKK23813.1 - 1 8.7 5.7 1.3 8.4 3.9 1.1 1 0 0 1 1 1 0 Coiled coil protein 84 Atrophin-1 PF03154.10 KKK23813.1 - 2.6 6.0 14.1 2.5 6.1 9.8 1.1 1 0 0 1 1 1 0 Atrophin-1 family DUF572 PF04502.8 KKK23813.1 - 4.1 6.5 6.6 4.9 6.2 4.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF1005 PF06219.7 KKK23813.1 - 4.6 5.7 13.9 7.8 5.0 9.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1005) Alpha-amylase PF00128.19 KKK23814.1 - 2.9e-16 59.7 0.5 4.2e-15 55.9 0.3 2.7 2 1 0 2 2 2 1 Alpha amylase, catalytic domain Glyco_transf_5 PF08323.6 KKK23814.1 - 4.8e-15 55.7 0.1 8.5e-15 54.9 0.1 1.4 1 0 0 1 1 1 1 Starch synthase catalytic domain Glyco_trans_1_4 PF13692.1 KKK23814.1 - 1e-06 28.9 0.0 2.5e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.15 KKK23814.1 - 4.2e-06 26.2 0.0 7.7e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Alpha-amylase PF00128.19 KKK23815.1 - 2.5e-55 188.0 2.8 3.4e-55 187.6 1.9 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.6 KKK23815.1 - 1.4e-28 98.8 0.0 3.5e-28 97.5 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) Glyco_hydro_61 PF03443.9 KKK23816.1 - 5.3e-81 271.5 0.3 6e-81 271.4 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 NARG2_C PF10505.4 KKK23816.1 - 0.11 11.6 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated gene protein 2 C-terminus Ribosomal_L38e PF01781.13 KKK23817.1 - 5e-32 109.4 1.8 6e-32 109.2 1.3 1.1 1 0 0 1 1 1 1 Ribosomal L38e protein family NMO PF03060.10 KKK23818.1 - 2.3e-74 250.5 0.4 2.7e-74 250.2 0.2 1.0 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 KKK23818.1 - 5e-07 28.9 0.2 1.5e-06 27.3 0.1 1.7 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 KKK23818.1 - 0.00064 18.6 3.0 0.0011 17.8 2.1 1.4 1 0 0 1 1 1 1 FMN-dependent dehydrogenase AP_endonuc_2 PF01261.19 KKK23818.1 - 0.037 13.3 0.0 0.074 12.3 0.0 1.5 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel Glu_synthase PF01645.12 KKK23818.1 - 0.13 11.1 0.7 0.22 10.4 0.5 1.3 1 0 0 1 1 1 0 Conserved region in glutamate synthase DNA_pol_E_B PF04042.11 KKK23819.1 - 1.3e-49 168.3 0.0 1.8e-49 167.8 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Acetyltransf_3 PF13302.1 KKK23820.1 - 7.9e-25 87.6 0.0 9.9e-25 87.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KKK23820.1 - 0.0023 17.8 0.1 0.018 14.9 0.1 2.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KKK23820.1 - 0.034 13.8 0.1 4.8 6.9 0.0 2.3 2 0 0 2 2 2 0 FR47-like protein Methyltransf_16 PF10294.4 KKK23821.1 - 1.4e-55 187.4 0.0 2.2e-55 186.7 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_31 PF13847.1 KKK23821.1 - 2.5e-05 23.8 0.0 3.7e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KKK23821.1 - 0.0099 16.4 0.0 0.022 15.3 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KKK23821.1 - 0.057 12.7 0.0 0.091 12.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_26 PF13659.1 KKK23821.1 - 0.061 13.3 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain M16C_assoc PF08367.6 KKK23823.1 - 2.2e-50 170.8 0.0 3.6e-50 170.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.16 KKK23823.1 - 6.8e-20 71.5 0.0 1e-08 35.1 0.0 2.7 2 0 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 KKK23823.1 - 1.2e-09 38.1 0.0 6.3e-09 35.7 0.0 2.2 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Taxilin PF09728.4 KKK23824.1 - 4.8e-106 354.3 52.0 4.8e-106 354.3 36.0 1.5 1 1 0 1 1 1 1 Myosin-like coiled-coil protein DUF4201 PF13870.1 KKK23824.1 - 2.6 7.4 57.4 0.012 15.0 11.0 4.7 1 1 4 5 5 5 0 Domain of unknown function (DUF4201) AA_permease PF00324.16 KKK23825.1 - 2.3e-96 323.0 37.7 2.8e-96 322.7 26.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KKK23825.1 - 2.5e-23 82.3 40.0 3.4e-23 81.8 27.7 1.0 1 0 0 1 1 1 1 Amino acid permease DUF1772 PF08592.6 KKK23825.1 - 0.068 12.9 15.7 0.067 12.9 0.9 4.2 4 0 0 4 4 4 0 Domain of unknown function (DUF1772) ADH_zinc_N PF00107.21 KKK23826.1 - 1.1e-27 96.1 0.2 1.6e-27 95.5 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KKK23826.1 - 1.6e-15 58.0 0.0 3.9e-15 56.8 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KKK23826.1 - 1.7e-12 47.0 0.1 5.6e-12 45.3 0.0 2.0 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.16 KKK23826.1 - 0.00045 19.8 0.1 0.00082 18.9 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.13 KKK23826.1 - 0.0026 17.7 0.0 0.0051 16.7 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain ELFV_dehydrog PF00208.16 KKK23826.1 - 0.014 15.0 0.0 0.023 14.2 0.0 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 2-Hacid_dh_C PF02826.14 KKK23826.1 - 0.038 13.1 0.0 0.058 12.5 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Raffinose_syn PF05691.7 KKK23827.1 - 3e-50 170.5 0.1 2.7e-43 147.5 0.0 2.5 2 1 1 3 3 3 2 Raffinose synthase or seed imbibition protein Sip1 Melibiase PF02065.13 KKK23827.1 - 0.00036 19.3 0.5 0.00059 18.6 0.4 1.2 1 0 0 1 1 1 1 Melibiase HAD_2 PF13419.1 KKK23830.1 - 1.2e-11 45.1 0.0 2e-10 41.1 0.0 2.0 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KKK23830.1 - 3.2e-06 26.7 0.3 5.3e-05 22.8 0.1 2.6 2 1 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.21 KKK23830.1 - 0.011 16.2 0.0 0.015 15.6 0.0 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase EBP PF05241.7 KKK23831.1 - 3.1e-64 215.5 8.7 3.5e-64 215.3 6.0 1.0 1 0 0 1 1 1 1 Emopamil binding protein TPR_11 PF13414.1 KKK23833.1 - 4.4e-12 45.4 4.9 2.4e-11 43.1 1.3 2.4 2 0 0 2 2 2 1 TPR repeat TPR_12 PF13424.1 KKK23833.1 - 3.5e-05 23.6 0.7 9.8e-05 22.2 0.5 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.23 KKK23833.1 - 0.00033 20.1 6.5 0.072 12.7 0.0 4.0 5 0 0 5 5 5 2 Tetratricopeptide repeat Apc3 PF12895.2 KKK23833.1 - 0.0019 18.2 1.3 0.0034 17.4 0.4 1.8 2 0 0 2 2 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 KKK23833.1 - 0.028 14.6 0.2 0.36 11.1 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 KKK23833.1 - 0.031 14.1 5.2 4.7 7.3 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.1 KKK23833.1 - 0.053 13.3 0.2 5.8 6.9 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF1250 PF06855.7 KKK23833.1 - 0.054 13.0 0.7 1.6 8.3 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1250) TPR_19 PF14559.1 KKK23833.1 - 0.059 13.7 0.2 0.059 13.7 0.1 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 KKK23833.1 - 0.12 13.1 4.1 1.2 9.9 0.1 2.7 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 KKK23833.1 - 2.3 8.8 5.7 11 6.6 0.0 3.5 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.1 KKK23833.1 - 3.3 7.6 5.7 6.2 6.7 0.1 3.2 3 1 1 4 4 4 0 Tetratricopeptide repeat Fer4_17 PF13534.1 KKK23833.1 - 3.7 7.9 7.8 18 5.7 0.3 2.9 2 1 0 3 3 3 0 4Fe-4S dicluster domain CAF-1_p150 PF11600.3 KKK23833.1 - 4.7 6.5 13.5 4.3 6.6 0.2 2.3 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Metal_resist PF13801.1 KKK23833.1 - 5.2 7.0 8.9 0.85 9.6 0.2 2.3 1 1 1 2 2 2 0 Heavy-metal resistance MFS_1 PF07690.11 KKK23834.1 - 6.9e-19 67.7 15.4 4.3e-10 38.8 7.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KKK23834.1 - 0.0015 17.0 0.1 0.0019 16.7 0.1 1.1 1 0 0 1 1 1 1 MFS/sugar transport protein ATG22 PF11700.3 KKK23834.1 - 0.057 11.9 3.4 1.3 7.3 0.3 2.4 1 1 1 2 2 2 0 Vacuole effluxer Atg22 like Mit_KHE1 PF10173.4 KKK23834.1 - 0.27 11.0 2.1 7.1 6.4 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial K+-H+ exchange-related NAD_binding_1 PF00175.16 KKK23835.1 - 5.8e-15 55.8 0.0 9e-15 55.1 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 KKK23835.1 - 5.6e-13 48.8 0.0 1e-12 48.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain PI31_Prot_N PF11566.3 KKK23836.1 - 1.7e-31 108.8 0.0 2.2e-31 108.5 0.0 1.1 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.6 KKK23836.1 - 1.2e-16 61.0 18.2 1.2e-16 61.0 12.6 3.0 3 1 0 3 3 3 1 PI31 proteasome regulator Metallophos PF00149.23 KKK23837.1 - 7.7e-44 149.4 0.8 1e-43 149.1 0.5 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase fn3_3 PF14686.1 KKK23838.1 - 2.3e-12 46.8 1.0 2.3e-12 46.8 0.7 2.1 2 0 0 2 2 2 1 Polysaccharide lyase family 4, domain II CBM-like PF14683.1 KKK23838.1 - 4.7e-11 42.6 0.0 1.2e-10 41.3 0.0 1.7 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain III CarboxypepD_reg PF13620.1 KKK23838.1 - 0.00037 20.5 0.1 0.0015 18.5 0.1 2.1 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain DUF2012 PF09430.5 KKK23838.1 - 0.063 13.1 0.1 0.37 10.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2012) Acyl-CoA_dh_1 PF00441.19 KKK23839.1 - 1.9e-22 79.9 0.5 6.8e-22 78.1 0.3 1.9 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cyt-b5 PF00173.23 KKK23839.1 - 2.9e-20 71.8 0.1 7.2e-20 70.5 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_M PF02770.14 KKK23839.1 - 5.5e-19 67.4 0.3 1.1e-18 66.4 0.2 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 KKK23839.1 - 3.4e-05 24.3 0.3 0.00011 22.6 0.0 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Tn916-Xis PF09035.5 KKK23839.1 - 0.027 14.5 0.0 0.058 13.4 0.0 1.5 1 0 0 1 1 1 0 Excisionase from transposon Tn916 Ferric_reduct PF01794.14 KKK23840.1 - 3.2e-21 75.7 13.6 3.2e-21 75.7 9.4 1.9 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 KKK23840.1 - 1.1e-15 57.8 0.0 1.8e-15 57.2 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 KKK23840.1 - 6.3e-10 38.8 0.0 0.0011 18.8 0.0 2.6 2 0 0 2 2 2 2 FAD-binding domain NAD_binding_1 PF00175.16 KKK23840.1 - 0.00045 20.7 0.0 0.027 15.0 0.0 2.3 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain TFCD_C PF12612.3 KKK23889.1 - 4.3e-37 127.4 0.5 2.8e-36 124.7 0.2 2.5 2 0 0 2 2 2 1 Tubulin folding cofactor D C terminal HEAT_2 PF13646.1 KKK23889.1 - 9e-06 25.8 8.3 0.038 14.2 0.1 5.1 4 1 1 5 5 5 2 HEAT repeats HEAT PF02985.17 KKK23889.1 - 3.2e-05 23.6 9.1 0.15 12.2 0.0 6.6 7 0 0 7 7 7 2 HEAT repeat HEAT_EZ PF13513.1 KKK23889.1 - 0.013 15.9 9.5 0.61 10.6 0.1 5.9 7 0 0 7 7 7 0 HEAT-like repeat HEAT_PBS PF03130.11 KKK23889.1 - 0.051 14.0 0.3 52 4.7 0.0 4.4 3 0 0 3 3 3 0 PBS lyase HEAT-like repeat Vac14_Fab1_bd PF12755.2 KKK23889.1 - 0.053 13.9 0.0 0.46 10.8 0.0 2.7 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region HMG_CoA_synt_N PF01154.12 KKK23889.1 - 0.1 12.1 0.0 1.3 8.6 0.0 2.6 3 0 0 3 3 3 0 Hydroxymethylglutaryl-coenzyme A synthase N terminal HR1 PF02185.11 KKK23892.1 - 3.8e-34 116.2 12.7 3.6e-19 68.2 3.2 2.5 2 0 0 2 2 2 2 Hr1 repeat C1_1 PF00130.17 KKK23892.1 - 3.3e-21 74.7 28.4 1.1e-11 44.2 6.4 2.2 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) UPF0547 PF10571.4 KKK23892.1 - 0.16 11.7 8.5 3.8 7.2 0.1 3.7 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 Uds1 PF15456.1 KKK23892.1 - 1.5 8.8 6.3 0.38 10.7 0.7 2.3 2 0 0 2 2 2 0 Up-regulated During Septation FYVE_2 PF02318.11 KKK23892.1 - 3.6 7.5 19.1 1.8 8.4 3.9 2.6 1 1 1 2 2 2 0 FYVE-type zinc finger DUF2076 PF09849.4 KKK23892.1 - 5.3 7.0 10.1 4.4 7.2 4.4 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) SNARE PF05739.14 KKK23893.1 - 1.7e-17 62.8 0.7 1.7e-17 62.8 0.5 2.2 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 KKK23893.1 - 1.1e-14 54.4 0.1 1.1e-14 54.4 0.0 2.8 3 1 0 3 3 3 1 Syntaxin MCPsignal PF00015.16 KKK23893.1 - 0.013 15.0 1.0 0.013 15.0 0.7 2.4 2 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain zf-C4H2 PF10146.4 KKK23893.1 - 0.017 15.1 0.6 0.38 10.7 0.0 2.4 1 1 1 2 2 2 0 Zinc finger-containing protein Sed5p PF11416.3 KKK23893.1 - 0.091 12.2 0.0 0.21 11.0 0.0 1.6 1 0 0 1 1 1 0 Integral membrane protein Sed5p KxDL PF10241.4 KKK23893.1 - 0.17 11.8 1.2 13 5.7 0.1 2.9 3 0 0 3 3 3 0 Uncharacterized conserved protein IncA PF04156.9 KKK23893.1 - 0.25 10.8 7.2 1.6 8.2 0.4 2.7 3 0 0 3 3 3 0 IncA protein NPV_P10 PF05531.7 KKK23893.1 - 0.26 11.5 4.8 18 5.6 0.1 3.3 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein ATG16 PF08614.6 KKK23893.1 - 4.1 7.1 12.7 0.74 9.6 2.0 2.7 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) Peptidase_M50B PF13398.1 KKK23894.1 - 2.4e-56 190.2 22.4 3e-56 189.9 15.6 1.1 1 0 0 1 1 1 1 Peptidase M50B-like Peptidase_M50 PF02163.17 KKK23894.1 - 0.11 11.5 9.4 0.042 12.7 3.3 2.7 2 1 0 2 2 2 0 Peptidase family M50 Peptidase_M41 PF01434.13 KKK23894.1 - 0.16 11.3 0.1 0.24 10.8 0.1 1.1 1 0 0 1 1 1 0 Peptidase family M41 YlaC PF10777.4 KKK23894.1 - 0.76 9.3 5.4 0.13 11.7 0.4 2.0 2 0 0 2 2 2 0 Inner membrane protein YlaC Patched PF02460.13 KKK23894.1 - 2.6 5.8 6.8 4 5.2 4.7 1.2 1 0 0 1 1 1 0 Patched family MLANA PF14991.1 KKK23894.1 - 4.6 7.2 9.3 1.2 9.1 1.1 2.4 1 1 1 2 2 2 0 Protein melan-A DUF1275 PF06912.6 KKK23895.1 - 6.5e-41 139.8 10.4 9.2e-41 139.3 7.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) DUF4131 PF13567.1 KKK23895.1 - 7.7 5.8 9.8 13 5.1 2.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) SUR7 PF06687.7 KKK23896.1 - 8.6e-31 107.1 9.5 1.1e-30 106.8 6.6 1.1 1 0 0 1 1 1 1 SUR7/PalI family NfeD PF01957.13 KKK23896.1 - 0.067 13.3 1.9 0.12 12.5 0.1 2.0 2 0 0 2 2 2 0 NfeD-like C-terminal, partner-binding SCIMP PF15050.1 KKK23896.1 - 0.11 12.4 0.1 0.11 12.4 0.0 2.4 2 1 0 2 2 2 0 SCIMP protein DUF4381 PF14316.1 KKK23896.1 - 8.8 6.4 6.0 0.81 9.7 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) Aminotran_1_2 PF00155.16 KKK23898.1 - 4.6e-59 200.2 0.0 5.6e-59 199.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 KKK23898.1 - 0.0015 16.8 0.0 0.0024 16.2 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Alliinase_C PF04864.8 KKK23898.1 - 0.048 12.2 0.0 0.07 11.7 0.0 1.1 1 0 0 1 1 1 0 Allinase Glyco_hydro_3 PF00933.16 KKK23899.1 - 6.2e-88 294.6 0.0 9.4e-88 294.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KKK23899.1 - 6.3e-63 212.3 0.4 2.9e-61 206.8 0.0 2.3 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KKK23899.1 - 4e-23 81.1 0.4 2e-22 78.9 0.1 2.2 2 0 0 2 2 2 1 Fibronectin type III-like domain PA14 PF07691.7 KKK23899.1 - 0.0028 17.3 0.0 0.0058 16.2 0.0 1.5 1 0 0 1 1 1 1 PA14 domain CARDB PF07705.6 KKK23899.1 - 0.046 13.7 0.1 0.23 11.5 0.0 2.2 2 0 0 2 2 2 0 CARDB Sec62 PF03839.11 KKK23949.1 - 2.4e-54 184.1 0.2 4.3e-54 183.3 0.2 1.4 1 0 0 1 1 1 1 Translocation protein Sec62 VIT1 PF01988.14 KKK23949.1 - 0.76 9.2 3.4 1.8 8.0 2.4 1.7 1 1 0 1 1 1 0 VIT family p450 PF00067.17 KKK23950.1 - 1.5e-05 23.7 0.0 1.8e-05 23.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 RHSP PF07999.6 KKK23950.1 - 0.034 12.7 0.0 0.043 12.4 0.0 1.1 1 0 0 1 1 1 0 Retrotransposon hot spot protein LEH PF07858.7 KKK23950.1 - 0.059 13.3 0.0 0.091 12.7 0.0 1.3 1 0 0 1 1 1 0 Limonene-1,2-epoxide hydrolase catalytic domain DUF726 PF05277.7 KKK23951.1 - 3.2e-113 378.1 0.6 4.1e-113 377.7 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Abhydrolase_6 PF12697.2 KKK23951.1 - 0.016 15.1 1.5 0.022 14.6 0.1 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase family DUF3353 PF11833.3 KKK23951.1 - 0.018 14.5 0.0 0.049 13.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3353) Abhydrolase_1 PF00561.15 KKK23951.1 - 0.11 12.0 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold SNAP PF14938.1 KKK23952.1 - 1.8e-113 378.3 14.4 2.1e-113 378.2 10.0 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_7 PF13176.1 KKK23952.1 - 3.5e-06 26.4 9.6 1.8 8.5 0.1 5.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_6 PF13174.1 KKK23952.1 - 3.8e-05 23.8 13.7 1 9.9 0.1 6.1 4 1 2 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.1 KKK23952.1 - 5.6e-05 22.7 17.6 0.049 13.2 1.2 4.0 2 2 1 3 3 3 3 TPR repeat TPR_12 PF13424.1 KKK23952.1 - 9.6e-05 22.2 18.8 0.033 14.1 4.9 4.0 1 1 3 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 KKK23952.1 - 0.0016 18.8 15.9 2.2 9.1 0.6 6.0 2 1 4 6 6 6 1 Tetratricopeptide repeat TPR_2 PF07719.12 KKK23952.1 - 0.0019 17.9 22.1 2.3 8.3 1.3 6.7 4 2 3 7 7 7 3 Tetratricopeptide repeat TPR_1 PF00515.23 KKK23952.1 - 0.0077 15.8 20.0 0.64 9.7 0.6 5.9 5 2 2 7 7 7 3 Tetratricopeptide repeat DUF1744 PF08490.7 KKK23952.1 - 0.023 13.2 0.1 0.035 12.7 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1744) DUF2811 PF10929.3 KKK23952.1 - 0.043 13.8 0.1 0.13 12.3 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2811) Imm16 PF15565.1 KKK23952.1 - 0.046 13.5 0.3 0.1 12.4 0.2 1.5 1 0 0 1 1 1 0 Immunity protein 16 TPR_16 PF13432.1 KKK23952.1 - 0.053 14.2 17.8 1.6 9.5 0.3 4.2 1 1 4 5 5 5 0 Tetratricopeptide repeat Apc3 PF12895.2 KKK23952.1 - 0.23 11.6 14.1 0.71 10.0 0.9 3.2 2 1 2 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 NSF PF02071.15 KKK23952.1 - 0.28 11.8 20.5 0.99 10.2 0.6 7.0 8 0 0 8 8 6 0 Aromatic-di-Alanine (AdAR) repeat TPR_8 PF13181.1 KKK23952.1 - 0.59 10.0 18.0 2.6 8.0 0.2 5.5 4 2 3 7 7 6 0 Tetratricopeptide repeat Glu-tRNAGln PF02686.10 KKK23953.1 - 3.2e-06 26.8 0.9 1.2e-05 25.0 0.2 2.0 2 0 0 2 2 2 1 Glu-tRNAGln amidotransferase C subunit MscS_porin PF12795.2 KKK23953.1 - 0.03 13.6 0.6 0.043 13.1 0.4 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain BING4CT PF08149.6 KKK23954.1 - 4.9e-38 128.4 0.0 2.3e-36 123.1 0.0 2.5 2 0 0 2 2 2 1 BING4CT (NUC141) domain WD40 PF00400.27 KKK23954.1 - 2.1e-05 24.2 0.1 0.019 14.8 0.0 3.7 5 0 0 5 5 5 2 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 KKK23954.1 - 0.0094 14.7 0.0 0.016 14.0 0.0 1.3 1 0 0 1 1 1 1 Coatomer WD associated region DUF4427 PF14468.1 KKK23954.1 - 0.096 12.4 0.0 0.25 11.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4427) DUF663 PF04950.7 KKK23955.1 - 2.7e-97 325.3 0.0 4.2e-97 324.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 KKK23955.1 - 1.7e-24 85.1 0.0 3.8e-24 84.0 0.0 1.6 1 0 0 1 1 1 1 AARP2CN (NUC121) domain MFS_1 PF07690.11 KKK23956.1 - 5.6e-25 87.8 26.2 1e-24 86.9 17.7 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily PsbN PF02468.10 KKK23956.1 - 0.94 9.1 4.2 5.4 6.7 0.7 3.0 2 1 0 2 2 2 0 Photosystem II reaction centre N protein (psbN) DUF2576 PF10845.3 KKK23957.1 - 0.024 13.7 0.2 0.065 12.4 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2576) PspA_IM30 PF04012.7 KKK23957.1 - 0.025 13.9 6.8 0.65 9.3 0.2 2.1 2 0 0 2 2 2 0 PspA/IM30 family DUF2046 PF09755.4 KKK23957.1 - 0.47 9.3 10.3 0.04 12.8 3.6 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein H4 (DUF2046) FlxA PF14282.1 KKK23957.1 - 1.7 8.6 17.9 4.6 7.2 0.4 2.5 2 0 0 2 2 2 0 FlxA-like protein DASH_Spc34 PF08657.5 KKK23957.1 - 2.8 7.5 9.8 3.7 7.1 2.7 2.2 2 0 0 2 2 2 0 DASH complex subunit Spc34 HOOK PF05622.7 KKK23957.1 - 4.2 5.0 9.5 0.93 7.2 0.1 2.0 2 0 0 2 2 2 0 HOOK protein DivIC PF04977.10 KKK23957.1 - 6.8 6.2 12.1 0.12 11.9 0.3 2.4 2 1 0 2 2 2 0 Septum formation initiator DUF2968 PF11180.3 KKK23957.1 - 8.7 5.6 20.6 0.21 10.9 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) Carn_acyltransf PF00755.15 KKK23958.1 - 2.3e-178 593.9 0.0 2.7e-178 593.7 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Rxt3 PF08642.5 KKK23959.1 - 5.5e-30 103.9 0.0 1.4e-29 102.6 0.0 1.7 1 0 0 1 1 1 1 Histone deacetylation protein Rxt3 LCCL PF03815.14 KKK23959.1 - 0.0012 18.8 0.0 0.0053 16.7 0.0 2.1 3 0 0 3 3 3 1 LCCL domain LIM_bind PF01803.11 KKK23960.1 - 3.1e-77 258.9 0.8 3.1e-77 258.9 0.5 4.3 3 2 1 4 4 4 1 LIM-domain binding protein Pyr_redox_2 PF07992.9 KKK23961.1 - 6.3e-07 29.4 0.0 1.8e-05 24.6 0.0 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KKK23961.1 - 9.7e-06 25.7 0.0 0.022 14.7 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KKK23961.1 - 0.00044 20.2 0.0 0.0011 18.9 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 KKK23961.1 - 0.0068 16.1 0.0 0.027 14.2 0.0 1.9 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 KKK23961.1 - 0.035 13.1 0.0 0.062 12.3 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.9 KKK23961.1 - 0.049 12.0 0.0 0.085 11.3 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein Cerato-platanin PF07249.7 KKK23962.1 - 4.4e-51 171.8 0.3 5.2e-51 171.6 0.2 1.1 1 0 0 1 1 1 1 Cerato-platanin Lectin_C PF00059.16 KKK23963.1 - 0.00075 20.1 0.4 0.0017 18.9 0.3 1.6 1 0 0 1 1 1 1 Lectin C-type domain Pkinase PF00069.20 KKK23964.1 - 9.4e-21 74.1 0.0 5.6e-20 71.5 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK23964.1 - 5.4e-07 28.9 0.1 1.5e-05 24.2 0.0 2.7 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KKK23964.1 - 0.00088 19.0 0.2 0.0022 17.7 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 KKK23964.1 - 0.13 11.6 0.1 0.49 9.7 0.0 1.8 2 0 0 2 2 2 0 RIO1 family Pterin_4a PF01329.14 KKK23965.1 - 6.5e-05 22.6 4.9 0.00097 18.8 0.3 2.5 2 1 0 2 2 2 1 Pterin 4 alpha carbinolamine dehydratase Peptidase_C2 PF00648.16 KKK23966.1 - 2.6e-23 82.4 0.0 9.6e-23 80.6 0.0 1.8 2 0 0 2 2 2 1 Calpain family cysteine protease Calpain_III PF01067.17 KKK23966.1 - 1.4e-16 60.4 0.0 3e-14 52.8 0.0 3.5 2 2 0 2 2 2 1 Calpain large subunit, domain III MIT PF04212.13 KKK23966.1 - 1e-09 38.0 6.2 1.6e-09 37.4 4.3 1.3 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain Mito_carr PF00153.22 KKK23967.1 - 2.3e-56 187.4 2.6 8.1e-22 76.7 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Fibrinogen_aC PF12160.3 KKK23967.1 - 0.017 14.6 2.1 2.5 7.6 0.1 2.3 2 0 0 2 2 2 0 Fibrinogen alpha C domain SNase PF00565.12 KKK23968.1 - 1.8e-18 66.7 0.7 2e-18 66.5 0.0 1.5 2 0 0 2 2 2 1 Staphylococcal nuclease homologue ADK PF00406.17 KKK23969.1 - 1.3e-34 119.2 0.0 3.3e-34 117.9 0.0 1.6 1 1 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 KKK23969.1 - 3.3e-14 52.2 0.0 5.5e-14 51.5 0.0 1.3 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.1 KKK23969.1 - 9.2e-06 25.9 0.0 2e-05 24.8 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KKK23969.1 - 0.0011 19.7 0.0 0.0023 18.7 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 KKK23969.1 - 0.003 17.4 0.0 0.0078 16.0 0.0 1.7 2 1 0 2 2 2 1 AAA domain Guanylate_kin PF00625.16 KKK23969.1 - 0.18 11.2 0.0 0.71 9.2 0.0 1.8 2 0 0 2 2 2 0 Guanylate kinase DNA_primase_lrg PF04104.9 KKK23970.1 - 9.2e-83 277.4 0.0 1.4e-82 276.8 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit Sec23_trunk PF04811.10 KKK23971.1 - 1.5e-80 270.0 0.0 2.3e-80 269.4 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 KKK23971.1 - 1.1e-33 114.7 0.1 2.3e-33 113.6 0.1 1.6 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 KKK23971.1 - 1.2e-29 102.5 0.1 2.7e-29 101.5 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Ribosomal_L11_N PF03946.9 KKK23971.1 - 2.1e-16 59.1 0.1 2.1e-16 59.1 0.1 1.9 2 0 0 2 2 2 1 Ribosomal protein L11, N-terminal domain zf-Sec23_Sec24 PF04810.10 KKK23971.1 - 5.1e-16 57.9 4.5 1.1e-15 56.9 3.1 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 KKK23971.1 - 1.6e-11 43.6 0.0 4.2e-11 42.3 0.0 1.8 1 0 0 1 1 1 1 Gelsolin repeat Ribosomal_L11 PF00298.14 KKK23971.1 - 7e-09 35.7 0.2 1.3e-08 34.8 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain DUF605 PF04652.11 KKK23972.1 - 8.8e-96 321.5 8.3 2.9e-89 300.1 4.0 2.0 2 0 0 2 2 2 2 Vta1 like MSA_2 PF00985.12 KKK23972.1 - 0.035 14.2 1.7 0.035 14.2 1.2 2.3 2 1 2 4 4 4 0 Merozoite Surface Antigen 2 (MSA-2) family Epimerase PF01370.16 KKK23974.1 - 3.6e-17 62.5 0.0 5.2e-17 62.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KKK23974.1 - 2.7e-08 32.8 0.0 5.3e-07 28.6 0.0 2.1 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 KKK23974.1 - 1e-05 25.5 0.0 3e-05 24.0 0.0 1.9 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KKK23974.1 - 0.016 14.8 0.0 0.059 13.0 0.0 1.8 2 0 0 2 2 2 0 KR domain Ldh_1_N PF00056.18 KKK23974.1 - 0.023 14.5 0.0 0.05 13.4 0.0 1.5 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Saccharop_dh PF03435.13 KKK23974.1 - 0.15 11.0 0.0 0.23 10.4 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase BRO1 PF03097.13 KKK24004.1 - 2.9e-05 23.0 0.1 3.8e-05 22.6 0.1 1.2 1 0 0 1 1 1 1 BRO1-like domain ECH PF00378.15 KKK24005.1 - 1.1e-20 73.8 0.0 1.3e-20 73.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Bromo_TP PF07524.8 KKK24007.1 - 2.4e-09 36.7 0.0 4.1e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated TAFII55_N PF04658.8 KKK24008.1 - 3.8e-51 172.8 0.0 7.8e-51 171.7 0.0 1.5 1 0 0 1 1 1 1 TAFII55 protein conserved region TPR_12 PF13424.1 KKK24026.1 - 7e-16 57.9 0.0 3.3e-10 39.7 0.0 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.1 KKK24026.1 - 1.1e-15 56.9 0.0 1.8e-05 24.4 0.0 4.8 5 0 0 5 5 4 3 Tetratricopeptide repeat PNP_UDP_1 PF01048.15 KKK24026.1 - 8.8e-13 47.7 0.4 7.2e-12 44.7 0.3 2.1 1 1 0 1 1 1 1 Phosphorylase superfamily NB-ARC PF00931.17 KKK24026.1 - 2.1e-12 46.5 0.0 3.3e-12 45.8 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.1 KKK24026.1 - 8.2e-08 32.4 0.2 1.6e-06 28.2 0.0 2.9 2 1 0 2 2 2 1 AAA ATPase domain NACHT PF05729.7 KKK24026.1 - 3.2e-07 30.1 0.0 6.7e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 NACHT domain TPR_11 PF13414.1 KKK24026.1 - 1e-06 28.3 0.0 2.9e-05 23.6 0.0 2.7 2 0 0 2 2 2 1 TPR repeat TPR_7 PF13176.1 KKK24026.1 - 2.1e-05 23.9 0.2 0.15 11.9 0.0 4.0 3 1 1 4 4 4 1 Tetratricopeptide repeat AAA_22 PF13401.1 KKK24026.1 - 6.6e-05 23.0 0.0 0.00022 21.3 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KKK24026.1 - 0.00018 21.3 0.0 0.00049 19.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain TPR_16 PF13432.1 KKK24026.1 - 0.0016 19.0 0.0 0.23 12.1 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 KKK24026.1 - 0.0044 16.8 0.1 2.8 8.0 0.0 3.6 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 KKK24026.1 - 0.007 16.7 0.0 0.9 10.1 0.0 3.5 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 KKK24026.1 - 0.0082 15.7 0.0 1.5 8.5 0.0 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat Arch_ATPase PF01637.13 KKK24026.1 - 0.011 15.3 0.0 0.025 14.2 0.0 1.6 1 1 0 1 1 1 0 Archaeal ATPase SRP54 PF00448.17 KKK24026.1 - 0.047 13.1 0.0 0.08 12.3 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_19 PF13245.1 KKK24026.1 - 0.061 13.0 0.0 0.27 11.0 0.0 2.1 2 0 0 2 2 2 0 Part of AAA domain AAA PF00004.24 KKK24026.1 - 0.071 13.3 0.0 0.28 11.3 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) CHZ PF09649.5 KKK24027.1 - 3e-18 64.7 1.2 3e-18 64.7 0.9 2.6 3 0 0 3 3 3 1 Histone chaperone domain CHZ BUD22 PF09073.5 KKK24027.1 - 2.3 7.1 19.5 2.7 6.9 13.5 1.0 1 0 0 1 1 1 0 BUD22 Mak16 PF04874.9 KKK24027.1 - 9.9 6.3 17.3 2.4 8.2 4.0 2.2 2 0 0 2 2 2 0 Mak16 protein C-terminal region HSP70 PF00012.15 KKK24028.1 - 9.6e-273 905.5 8.2 1.1e-272 905.3 5.7 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KKK24028.1 - 1.3e-18 66.7 0.0 1.4e-17 63.2 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 KKK24028.1 - 0.00053 19.6 0.0 0.0022 17.6 0.0 2.0 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.1 KKK24028.1 - 0.00079 19.2 1.3 0.6 9.9 0.0 3.4 2 2 0 2 2 2 2 Cell division protein FtsA Hydantoinase_A PF01968.13 KKK24028.1 - 0.0063 15.6 0.1 0.042 12.9 0.0 2.2 1 1 1 2 2 2 1 Hydantoinase/oxoprolinase BcrAD_BadFG PF01869.15 KKK24028.1 - 0.031 13.5 0.0 0.59 9.3 0.0 2.4 1 1 1 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family WD40 PF00400.27 KKK24029.1 - 1.6e-20 72.1 0.4 4.7e-08 32.6 0.0 6.8 7 0 0 7 7 7 4 WD domain, G-beta repeat DUF3639 PF12341.3 KKK24029.1 - 6.2e-09 35.6 0.2 6.2e-09 35.6 0.2 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF3639) Coatomer_WDAD PF04053.9 KKK24029.1 - 8.2e-07 28.1 0.0 1.8e-05 23.7 0.0 2.2 1 1 1 2 2 2 1 Coatomer WD associated region eIF2A PF08662.6 KKK24029.1 - 7.3e-06 25.8 0.1 0.0016 18.1 0.0 3.0 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A DNA_pol_alpha_N PF12254.3 KKK24029.1 - 0.007 16.1 1.7 0.018 14.8 1.1 1.6 1 0 0 1 1 1 1 DNA polymerase alpha subunit p180 N terminal DUF3312 PF11768.3 KKK24029.1 - 0.0078 14.4 0.0 0.73 7.9 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3312) IKI3 PF04762.7 KKK24029.1 - 0.023 12.5 0.5 0.073 10.8 0.0 2.0 2 1 0 2 2 2 0 IKI3 family Lactonase PF10282.4 KKK24029.1 - 0.031 13.3 0.0 0.33 9.9 0.0 2.2 1 1 1 2 2 2 0 Lactonase, 7-bladed beta-propeller Apc4_WD40 PF12894.2 KKK24029.1 - 0.086 12.3 0.0 0.55 9.7 0.0 2.2 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain TFIIIC_delta PF12657.2 KKK24029.1 - 0.086 12.5 0.0 1.2 8.7 0.0 2.8 3 0 0 3 3 3 0 Transcription factor IIIC subunit delta N-term MMS1_N PF10433.4 KKK24029.1 - 0.12 10.5 0.0 0.68 8.0 0.0 2.2 3 0 0 3 3 3 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term PD40 PF07676.7 KKK24029.1 - 0.12 12.0 0.2 8.3 6.2 0.0 3.7 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat DUF4613 PF15390.1 KKK24029.1 - 0.26 9.4 0.0 1.4 6.9 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4613) ILVD_EDD PF00920.16 KKK24030.1 - 3e-167 557.1 0.6 3.4e-167 556.9 0.4 1.0 1 0 0 1 1 1 1 Dehydratase family SNARE PF05739.14 KKK24032.1 - 3.7e-06 26.5 1.9 5.3e-06 26.0 1.3 1.3 1 0 0 1 1 1 1 SNARE domain MFS_1 PF07690.11 KKK24033.1 - 2.3e-39 135.1 33.0 4.1e-38 130.9 15.0 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KKK24033.1 - 2.7e-05 22.9 9.5 2.7e-05 22.9 6.6 2.0 1 1 1 2 2 2 1 Sugar (and other) transporter DUF791 PF05631.9 KKK24033.1 - 0.0091 14.7 0.8 0.0091 14.7 0.5 1.8 3 0 0 3 3 3 1 Protein of unknown function (DUF791) DUF1129 PF06570.6 KKK24033.1 - 0.016 14.4 0.7 3.1 7.0 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) zf-met PF12874.2 KKK24037.1 - 1.9e-05 24.6 0.6 3.7e-05 23.7 0.4 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type PRP4 PF08799.6 KKK24037.1 - 0.046 12.9 0.9 0.094 12.0 0.6 1.6 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like DNA_ligase_OB_2 PF14743.1 KKK24037.1 - 0.1 12.2 0.1 0.74 9.5 0.0 2.2 2 0 0 2 2 2 0 DNA ligase OB-like domain Pkinase PF00069.20 KKK24038.1 - 7.1e-54 182.6 0.2 9.5e-38 129.8 0.1 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KKK24038.1 - 9.4e-25 87.1 0.4 1.5e-19 70.1 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KKK24038.1 - 6.4e-05 22.0 0.0 0.00013 21.0 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KKK24038.1 - 0.00027 20.0 0.0 0.0006 18.9 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KKK24038.1 - 0.00031 20.5 0.2 0.011 15.5 0.1 2.4 1 1 0 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 KKK24038.1 - 0.0043 15.9 0.0 0.0071 15.2 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Pkinase_C PF00433.19 KKK24038.1 - 0.013 15.9 0.0 0.037 14.5 0.0 1.8 1 0 0 1 1 1 0 Protein kinase C terminal domain Pox_ser-thr_kin PF05445.6 KKK24038.1 - 0.078 11.7 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase RIO1 PF01163.17 KKK24038.1 - 0.098 11.9 1.3 0.23 10.7 0.0 2.0 2 0 0 2 2 2 0 RIO1 family DUF3441 PF11923.3 KKK24038.1 - 0.14 11.7 0.1 0.27 10.8 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3441) SpoIIIAH PF12685.2 KKK24038.1 - 0.19 11.1 0.9 0.31 10.5 0.7 1.3 1 0 0 1 1 1 0 SpoIIIAH-like protein Tim54 PF11711.3 KKK24039.1 - 1.7e-133 444.9 1.5 4.7e-132 440.1 1.0 2.0 1 1 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 Fungal_trans PF04082.13 KKK24040.1 - 4.1e-20 71.7 6.9 6.4e-20 71.1 4.8 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK24040.1 - 2.8e-08 33.5 8.5 2.8e-08 33.5 5.9 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CAP_GLY PF01302.20 KKK24041.1 - 5.2e-20 70.9 0.2 1.2e-19 69.7 0.1 1.6 1 0 0 1 1 1 1 CAP-Gly domain LRR_4 PF12799.2 KKK24041.1 - 3.9e-08 32.7 22.3 0.00024 20.6 1.0 5.8 4 2 2 6 6 6 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KKK24041.1 - 4.2e-08 32.8 12.5 2.2e-05 24.0 2.4 4.4 2 2 3 5 5 5 5 Leucine rich repeat zf-U1 PF06220.7 KKK24041.1 - 7.9e-06 25.3 0.1 1.4e-05 24.5 0.1 1.4 1 0 0 1 1 1 1 U1 zinc finger LRR_1 PF00560.28 KKK24041.1 - 1.8e-05 24.1 8.4 2.9 8.2 0.2 6.3 7 0 0 7 7 7 2 Leucine Rich Repeat LRR_6 PF13516.1 KKK24041.1 - 0.0003 20.5 12.6 1.3 9.2 0.3 7.2 8 0 0 8 8 8 1 Leucine Rich repeat LRR_7 PF13504.1 KKK24041.1 - 0.0036 17.2 9.4 4.4 7.9 0.1 6.4 6 1 0 6 6 6 1 Leucine rich repeat LRR_9 PF14580.1 KKK24041.1 - 0.0057 16.2 2.2 3.7 7.0 0.3 3.4 2 1 2 4 4 4 2 Leucine-rich repeat bZIP_1 PF00170.16 KKK24042.1 - 4.2e-08 33.0 9.3 7.6e-08 32.1 6.4 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KKK24042.1 - 2.5e-06 27.1 10.2 7.8e-06 25.6 7.1 1.8 1 0 0 1 1 1 1 Basic region leucine zipper TPR_14 PF13428.1 KKK24042.1 - 0.0094 16.5 1.1 0.022 15.3 0.8 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat VPS9 PF02204.13 KKK24043.1 - 6.5e-31 106.4 0.0 1.1e-30 105.7 0.0 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain CUE PF02845.11 KKK24043.1 - 1.6e-09 37.0 0.3 2.5e-08 33.2 0.0 2.3 2 0 0 2 2 2 1 CUE domain Fungal_trans PF04082.13 KKK24044.1 - 1.4e-20 73.3 0.2 2.2e-20 72.6 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK24044.1 - 9.4e-10 38.2 12.3 1.7e-09 37.4 8.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain IFP_35_N PF07334.8 KKK24044.1 - 0.16 11.9 0.3 0.45 10.5 0.2 1.7 1 0 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Asn_synthase PF00733.16 KKK24045.1 - 1.8e-52 178.3 0.0 2.4e-52 177.9 0.0 1.1 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 KKK24045.1 - 2.1e-07 30.7 0.0 2e-06 27.5 0.0 2.4 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_6 PF13522.1 KKK24045.1 - 2.5e-06 27.4 0.0 0.0002 21.3 0.0 3.0 4 0 0 4 4 4 1 Glutamine amidotransferase domain DUF3700 PF12481.3 KKK24045.1 - 1.3e-05 24.5 0.0 2.4e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Aluminium induced protein VIT1 PF01988.14 KKK24047.1 - 5.7e-44 150.1 2.8 7.6e-44 149.7 2.0 1.1 1 0 0 1 1 1 1 VIT family DUF4202 PF13875.1 KKK24048.1 - 6e-53 179.2 0.0 4.9e-31 107.8 0.0 2.0 1 1 1 2 2 2 2 Domain of unknown function (DUF4202) Rox3 PF08633.5 KKK24049.1 - 5.5e-57 193.2 0.7 5.5e-57 193.2 0.5 1.7 2 1 0 2 2 2 1 Rox3 mediator complex subunit PBP1_TM PF14812.1 KKK24049.1 - 0.11 12.8 4.0 0.15 12.3 1.2 2.1 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Trp_DMAT PF11991.3 KKK24070.1 - 2.6e-71 240.7 0.0 2.2e-70 237.7 0.0 1.9 2 0 0 2 2 2 1 Tryptophan dimethylallyltransferase GTP_EFTU_D3 PF03143.12 KKK24076.1 - 4.2e-16 58.9 0.6 5e-16 58.6 0.0 1.4 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain Adaptin_N PF01602.15 KKK24083.1 - 1.1e-34 119.6 0.2 1.3e-34 119.4 0.2 1.0 1 0 0 1 1 1 1 Adaptin N terminal region DUF1160 PF06648.6 KKK24083.1 - 0.031 14.0 0.6 0.052 13.3 0.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1160) Dak1 PF02733.12 KKK24084.1 - 1e-113 379.2 0.6 1.8e-113 378.3 0.4 1.4 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.12 KKK24084.1 - 1.2e-44 152.0 0.2 2.4e-44 151.0 0.2 1.5 1 0 0 1 1 1 1 DAK2 domain Prp19_bind PF06991.6 KKK24085.1 - 5.7e-46 157.0 27.8 5.7e-46 157.0 19.3 3.1 3 0 0 3 3 3 2 Splicing factor, Prp19-binding domain Rep_fac-A_3 PF08661.6 KKK24086.1 - 1.7e-23 82.5 0.0 1.9e-23 82.4 0.0 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 Ten1 PF12658.2 KKK24086.1 - 0.1 12.3 0.0 1.2 8.8 0.0 2.0 1 1 0 1 1 1 0 Telomere capping, CST complex subunit GATA PF00320.22 KKK24087.1 - 4.4e-06 25.9 4.3 0.00022 20.4 0.6 2.5 2 0 0 2 2 2 2 GATA zinc finger Mucin PF01456.12 KKK24094.1 - 0.027 14.2 20.4 0.039 13.7 14.2 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein PAP1 PF08601.5 KKK24094.1 - 0.15 11.6 8.3 0.17 11.5 5.8 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 CytochromB561_N PF09786.4 KKK24094.1 - 0.2 10.0 6.3 0.23 9.8 4.3 1.0 1 0 0 1 1 1 0 Cytochrome B561, N terminal DNA_pol_viral_N PF00242.12 KKK24094.1 - 0.49 9.3 5.7 0.56 9.1 4.0 1.0 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Pex14_N PF04695.8 KKK24094.1 - 0.83 9.6 6.4 1.2 9.2 4.4 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Sporozoite_P67 PF05642.6 KKK24094.1 - 3.6 5.3 13.8 4 5.1 9.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen AAA_17 PF13207.1 KKK24095.1 - 0.00076 20.2 0.8 0.0044 17.8 0.6 2.2 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KKK24095.1 - 0.00085 19.6 0.0 0.015 15.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain PRK PF00485.13 KKK24095.1 - 0.0048 16.4 0.0 0.0068 15.9 0.0 1.3 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family NB-ARC PF00931.17 KKK24095.1 - 0.038 12.8 0.0 0.06 12.2 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain T2SE PF00437.15 KKK24095.1 - 0.045 12.6 0.0 0.072 11.9 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF2075 PF09848.4 KKK24095.1 - 0.047 12.6 0.0 0.072 12.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Zeta_toxin PF06414.7 KKK24095.1 - 0.055 12.5 0.1 0.22 10.6 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin AAA_33 PF13671.1 KKK24095.1 - 0.069 13.0 0.1 1.5 8.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 KKK24095.1 - 0.075 13.1 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.7 KKK24095.1 - 0.099 11.6 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus Transpeptidase PF00905.17 KKK24095.1 - 0.13 11.2 0.0 0.18 10.7 0.0 1.2 1 0 0 1 1 1 0 Penicillin binding protein transpeptidase domain DPBB_1 PF03330.13 KKK24096.1 - 4.3e-06 26.6 0.0 2.5e-05 24.1 0.0 2.4 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel TFIIA PF03153.8 KKK24096.1 - 0.81 9.5 14.9 0.94 9.3 10.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ribonuc_red_lgC PF02867.10 KKK24097.1 - 3.4e-215 715.6 0.0 6.3e-215 714.8 0.0 1.4 2 0 0 2 2 2 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 KKK24097.1 - 3.4e-24 84.4 0.0 8e-24 83.2 0.0 1.7 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.11 KKK24097.1 - 7.4e-17 61.5 0.1 2.4e-16 59.9 0.0 2.0 1 0 0 1 1 1 1 ATP cone domain ELFV_dehydrog PF00208.16 KKK24098.1 - 2.4e-84 282.7 1.5 3e-84 282.4 1.1 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.13 KKK24098.1 - 5.3e-48 161.9 0.0 9.5e-48 161.0 0.0 1.4 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain MFS_1 PF07690.11 KKK24099.1 - 4.8e-16 58.4 32.3 4.8e-16 58.4 22.4 4.0 3 1 1 4 4 4 1 Major Facilitator Superfamily Pam17 PF08566.5 KKK24099.1 - 0.036 13.7 0.1 0.13 11.9 0.0 2.0 1 0 0 1 1 1 0 Mitochondrial import protein Pam17 Med5 PF08689.5 KKK24100.1 - 0 1154.5 0.0 0 1154.2 0.0 1.0 1 0 0 1 1 1 1 Mediator complex subunit Med5 zf-CCCH PF00642.19 KKK24100.1 - 0.23 11.1 0.1 0.49 10.1 0.1 1.5 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Mur_ligase_M PF08245.7 KKK24103.1 - 1.1e-06 28.8 0.5 2.2e-06 27.8 0.3 1.6 1 1 0 1 1 1 1 Mur ligase middle domain AAA_10 PF12846.2 KKK24103.1 - 0.15 11.4 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain ABC1 PF03109.11 KKK24104.1 - 2.1e-32 111.5 0.0 3.9e-32 110.7 0.0 1.5 1 0 0 1 1 1 1 ABC1 family RIO1 PF01163.17 KKK24104.1 - 0.12 11.6 0.0 0.24 10.7 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Pkinase PF00069.20 KKK24105.1 - 1.8e-70 237.1 0.0 5.4e-70 235.4 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK24105.1 - 1.4e-50 171.7 0.0 2.9e-50 170.7 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KKK24105.1 - 0.0025 16.8 0.0 0.013 14.4 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Mito_carr PF00153.22 KKK24106.1 - 3e-62 206.3 0.0 1.2e-23 82.6 0.0 3.4 2 2 1 3 3 3 3 Mitochondrial carrier protein Shisa PF13908.1 KKK24107.1 - 0.013 15.6 0.9 0.015 15.4 0.6 1.1 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator SR-25 PF10500.4 KKK24107.1 - 0.016 14.6 9.0 0.019 14.4 6.2 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein ERbeta_N PF12497.3 KKK24107.1 - 0.032 14.0 0.9 0.038 13.8 0.6 1.1 1 0 0 1 1 1 0 Estrogen receptor beta PP_kinase_N PF13089.1 KKK24107.1 - 0.049 13.7 0.7 0.064 13.3 0.5 1.1 1 0 0 1 1 1 0 Polyphosphate kinase N-terminal domain Calc_CGRP_IAPP PF00214.14 KKK24107.1 - 0.11 12.5 1.5 0.13 12.2 1.0 1.1 1 0 0 1 1 1 0 Calcitonin / CGRP / IAPP family WBP-1 PF11669.3 KKK24107.1 - 0.36 10.9 3.4 0.51 10.4 0.0 1.9 1 1 1 2 2 2 0 WW domain-binding protein 1 BNIP3 PF06553.7 KKK24107.1 - 5.6 6.3 8.6 7.2 5.9 6.0 1.1 1 0 0 1 1 1 0 BNIP3 UCR_14kD PF02271.11 KKK24108.1 - 2.7e-46 155.6 0.1 3e-46 155.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit ArfGap PF01412.13 KKK24111.1 - 1e-34 118.8 0.1 1e-34 118.8 0.1 2.3 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf PH PF00169.24 KKK24111.1 - 2.6e-12 46.8 0.8 6.6e-12 45.5 0.1 2.1 2 0 0 2 2 2 1 PH domain YTH PF04146.10 KKK24112.1 - 4.8e-51 172.0 0.0 8.1e-51 171.2 0.0 1.3 1 0 0 1 1 1 1 YT521-B-like domain RRM_1 PF00076.17 KKK24112.1 - 7.5e-07 28.6 0.0 1.4e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KKK24112.1 - 1.1e-05 25.3 0.0 2.7e-05 24.0 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nucleoplasmin PF03066.10 KKK24112.1 - 0.0085 15.6 1.5 0.013 15.0 1.0 1.3 1 0 0 1 1 1 1 Nucleoplasmin RRM_5 PF13893.1 KKK24112.1 - 0.019 14.7 0.0 0.035 13.9 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SNF2_N PF00176.18 KKK24113.1 - 2.1e-63 213.9 0.2 4e-63 213.0 0.1 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KKK24113.1 - 1.8e-12 46.9 0.0 6.5e-12 45.1 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.20 KKK24113.1 - 2.6e-05 23.7 10.5 2.6e-05 23.7 7.2 2.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KKK24113.1 - 0.0027 17.4 11.7 0.0027 17.4 8.1 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 KKK24113.1 - 0.0053 16.7 11.6 0.0053 16.7 8.1 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) C2 PF00168.25 KKK24114.1 - 5.6e-09 35.7 0.0 1.1e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 C2 domain LRR_6 PF13516.1 KKK24117.1 - 0.00037 20.2 6.7 8.9 6.7 0.1 6.6 9 0 0 9 9 9 2 Leucine Rich repeat FYVE PF01363.16 KKK24117.1 - 0.09 12.6 0.2 0.09 12.6 0.1 2.0 2 0 0 2 2 2 0 FYVE zinc finger LRR_4 PF12799.2 KKK24117.1 - 0.85 9.3 9.5 3.4 7.3 0.1 5.3 4 1 3 7 7 7 0 Leucine Rich repeats (2 copies) CDC45 PF02724.9 KKK24117.1 - 3.4 5.6 6.2 18 3.1 4.6 1.8 2 0 0 2 2 2 0 CDC45-like protein Glyco_transf_20 PF00982.16 KKK24118.1 - 5.1e-159 529.7 0.0 6.8e-159 529.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 KKK24118.1 - 3e-26 91.7 0.0 4.9e-26 91.0 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase Hydrolase_3 PF08282.7 KKK24118.1 - 0.099 12.2 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Glycophorin_A PF01102.13 KKK24119.1 - 0.004 16.9 6.0 0.0063 16.2 4.2 1.3 1 0 0 1 1 1 1 Glycophorin A Pex14_N PF04695.8 KKK24119.1 - 0.15 12.1 3.2 0.2 11.6 2.2 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Pox_A12 PF04651.8 KKK24119.1 - 0.2 11.7 7.0 0.3 11.1 4.8 1.2 1 0 0 1 1 1 0 Poxvirus A12 protein Sporozoite_P67 PF05642.6 KKK24119.1 - 0.78 7.5 12.2 0.89 7.3 8.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Pap_E4 PF02711.9 KKK24119.1 - 2.4 9.0 9.3 4.7 8.0 6.4 1.5 1 0 0 1 1 1 0 E4 protein TMEM154 PF15102.1 KKK24119.1 - 6.8 6.3 7.5 9.9 5.8 5.2 1.4 1 0 0 1 1 1 0 TMEM154 protein family Na_Ca_ex PF01699.19 KKK24120.1 - 3.2e-45 153.1 37.1 1.9e-23 82.6 7.9 2.8 3 0 0 3 3 3 2 Sodium/calcium exchanger protein Cnd2 PF05786.9 KKK24121.1 - 3.6e-275 915.0 0.3 4.2e-275 914.8 0.2 1.0 1 0 0 1 1 1 1 Condensin complex subunit 2 RNA_pol_L_2 PF13656.1 KKK24122.1 - 7e-23 79.8 0.0 1.1e-22 79.2 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 KKK24122.1 - 9.2e-13 47.1 0.0 1.9e-12 46.0 0.0 1.5 2 0 0 2 2 2 1 RNA polymerase Rpb3/Rpb11 dimerisation domain EF-hand_4 PF12763.2 KKK24123.1 - 5.6e-27 93.5 0.0 8.2e-13 48.0 0.0 2.4 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand DUF1720 PF08226.6 KKK24123.1 - 9.8e-12 44.7 117.0 1.3e-05 25.1 18.7 6.8 4 1 1 5 5 5 4 Domain of unknown function (DUF1720) WH2 PF02205.15 KKK24123.1 - 3.3e-10 39.2 0.4 7.3e-10 38.1 0.3 1.6 1 0 0 1 1 1 1 WH2 motif EF-hand_7 PF13499.1 KKK24123.1 - 4.1e-05 23.6 0.1 0.0049 16.9 0.0 2.7 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 KKK24123.1 - 0.072 12.4 0.0 11 5.5 0.0 2.5 2 0 0 2 2 2 0 EF hand zf-H2C2_2 PF13465.1 KKK24124.1 - 6.9e-06 26.0 0.4 2.1e-05 24.5 0.3 1.9 1 0 0 1 1 1 1 Zinc-finger double domain zf-C2H2 PF00096.21 KKK24124.1 - 0.0012 19.0 0.1 0.0036 17.5 0.1 1.8 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KKK24124.1 - 0.0036 17.5 0.2 0.0085 16.3 0.1 1.7 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KKK24124.1 - 0.016 15.0 0.1 0.028 14.3 0.1 1.3 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2HC_2 PF13913.1 KKK24124.1 - 0.024 14.3 1.8 0.024 14.3 1.3 2.3 2 0 0 2 2 2 0 zinc-finger of a C2HC-type DUF3074 PF11274.3 KKK24125.1 - 1.6e-43 148.5 0.0 1.9e-43 148.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3074) MARVEL PF01284.18 KKK24126.1 - 0.00014 21.7 5.1 0.0054 16.5 2.6 2.3 2 0 0 2 2 2 1 Membrane-associating domain DUF1191 PF06697.7 KKK24126.1 - 0.017 13.9 0.3 0.97 8.1 0.0 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1191) DUF981 PF06168.6 KKK24126.1 - 0.06 13.1 1.5 0.093 12.5 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF981) DUF2371 PF10177.4 KKK24126.1 - 0.11 12.3 0.0 0.34 10.7 0.0 1.8 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2371) SPC25 PF06703.6 KKK24126.1 - 0.16 11.5 1.1 0.36 10.3 0.8 1.6 1 0 0 1 1 1 0 Microsomal signal peptidase 25 kDa subunit (SPC25) Ndc1_Nup PF09531.5 KKK24126.1 - 0.17 10.2 6.0 0.35 9.2 4.2 1.5 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup PEN-2 PF10251.4 KKK24126.1 - 0.25 11.5 6.8 0.2 11.9 2.7 2.1 2 0 0 2 2 2 0 Presenilin enhancer-2 subunit of gamma secretase DUF2254 PF10011.4 KKK24126.1 - 0.28 9.6 1.5 0.8 8.1 0.9 1.7 2 0 0 2 2 2 0 Predicted membrane protein (DUF2254) Tic20 PF09685.5 KKK24126.1 - 0.57 10.1 8.1 0.038 13.9 0.7 2.1 1 1 0 2 2 2 0 Tic20-like protein DUF1772 PF08592.6 KKK24126.1 - 0.67 9.6 4.3 0.45 10.2 1.6 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1772) DUF4381 PF14316.1 KKK24126.1 - 1.2 9.2 3.7 9.9 6.2 0.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) DUF202 PF02656.10 KKK24126.1 - 1.4 9.1 15.6 14 5.9 5.9 3.2 1 1 1 2 2 2 0 Domain of unknown function (DUF202) DUF382 PF04037.8 KKK24130.1 - 1.4e-60 202.7 0.8 2.7e-60 201.8 0.5 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF382) PSP PF04046.11 KKK24130.1 - 1.4e-20 72.4 9.8 3.8e-20 71.0 6.8 1.8 1 0 0 1 1 1 1 PSP SPT16 PF08644.6 KKK24131.1 - 6.6e-60 201.3 0.0 1.6e-59 200.1 0.0 1.7 1 0 0 1 1 1 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.1 KKK24131.1 - 2.4e-52 176.7 0.0 1e-51 174.7 0.0 2.2 1 0 0 1 1 1 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.19 KKK24131.1 - 6.4e-23 81.4 0.0 1.1e-22 80.6 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.7 KKK24131.1 - 3e-19 68.7 0.0 9.2e-19 67.2 0.0 1.9 1 0 0 1 1 1 1 Histone chaperone Rttp106-like DUF3956 PF13104.1 KKK24131.1 - 0.14 11.6 0.0 0.31 10.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3956) Peptidase_M43 PF05572.8 KKK24132.1 - 4.2e-13 49.1 0.0 9.8e-13 47.9 0.0 1.6 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_4 PF13583.1 KKK24132.1 - 0.0001 21.9 0.8 0.00025 20.6 0.6 1.8 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 KKK24132.1 - 0.0015 18.4 4.0 0.0054 16.6 2.8 2.0 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.1 KKK24132.1 - 0.011 16.2 0.2 0.024 15.1 0.2 1.6 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 KKK24132.1 - 0.012 15.7 2.5 0.023 14.7 1.6 1.8 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like CDC50 PF03381.10 KKK24133.1 - 4.2e-100 334.5 0.0 5.2e-100 334.1 0.0 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family DUF4282 PF14110.1 KKK24133.1 - 0.17 12.0 1.7 3.1 8.0 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4282) SWIRM PF04433.12 KKK24134.1 - 1.2e-14 54.1 0.0 2.1e-14 53.3 0.0 1.4 1 0 0 1 1 1 1 SWIRM domain Choline_transpo PF04515.7 KKK24135.1 - 4e-08 32.3 17.3 4e-08 32.3 12.0 3.0 3 0 0 3 3 3 2 Plasma-membrane choline transporter Ras PF00071.17 KKK24136.1 - 6.7e-48 162.1 0.0 6.1e-37 126.4 0.0 2.1 2 0 0 2 2 2 2 Ras family Miro PF08477.8 KKK24136.1 - 9e-16 58.4 0.0 2.3e-10 41.0 0.0 2.2 2 0 0 2 2 2 2 Miro-like protein Arf PF00025.16 KKK24136.1 - 2.9e-11 42.8 0.0 1.7e-10 40.3 0.0 1.9 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KKK24136.1 - 7.7e-10 38.5 0.0 5.1e-09 35.8 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 KKK24136.1 - 2.2e-06 27.0 0.0 6.1e-06 25.5 0.0 1.7 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KKK24136.1 - 0.00026 20.9 0.0 0.0016 18.4 0.0 2.1 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.1 KKK24136.1 - 0.022 14.9 0.1 0.14 12.3 0.0 2.1 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.1 KKK24136.1 - 0.054 12.8 0.0 10 5.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 KKK24136.1 - 0.063 12.4 0.1 0.15 11.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Flu_M1_C PF08289.6 KKK24136.1 - 0.092 12.7 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Influenza Matrix protein (M1) C-terminal domain PMT PF02366.13 KKK24137.1 - 5.2e-83 278.1 17.9 5.2e-83 278.1 12.4 2.2 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 KKK24137.1 - 2.1e-39 135.0 0.3 2.9e-39 134.5 0.2 1.2 1 0 0 1 1 1 1 MIR domain Sugar_tr PF00083.19 KKK24138.1 - 1.4e-100 337.0 12.1 1.8e-100 336.6 8.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KKK24138.1 - 9.8e-32 110.0 25.0 1.7e-31 109.2 12.4 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Mito_carr PF00153.22 KKK24138.1 - 1.7e-19 69.3 0.0 2.4e-13 49.6 0.0 3.1 2 0 0 2 2 2 2 Mitochondrial carrier protein MFS_1_like PF12832.2 KKK24138.1 - 0.0094 15.7 0.4 0.035 13.8 0.1 2.1 2 0 0 2 2 2 1 MFS_1 like family Pro_isomerase PF00160.16 KKK24151.1 - 1.9e-29 102.8 0.0 9.7e-26 90.8 0.0 2.1 2 0 0 2 2 2 2 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF2419 PF10343.4 KKK24152.1 - 3.9e-145 482.5 0.0 4.8e-145 482.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2419) DUF1563 PF07599.6 KKK24152.1 - 0.19 11.6 0.8 0.35 10.7 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1563) ORC6 PF05460.8 KKK24153.1 - 2e-98 329.7 0.1 2.5e-98 329.4 0.1 1.0 1 0 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) Zn_clus PF00172.13 KKK24154.1 - 0.00028 20.7 7.5 0.00046 20.0 5.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HALZ PF02183.13 KKK24154.1 - 0.0027 17.3 1.4 0.043 13.5 0.1 2.3 1 1 1 2 2 2 2 Homeobox associated leucine zipper DivIC PF04977.10 KKK24154.1 - 0.022 14.2 0.7 0.044 13.2 0.5 1.4 1 0 0 1 1 1 0 Septum formation initiator MbeD_MobD PF04899.7 KKK24154.1 - 0.039 13.8 0.5 0.091 12.6 0.3 1.6 1 0 0 1 1 1 0 MbeD/MobD like ADIP PF11559.3 KKK24154.1 - 0.048 13.5 0.9 0.048 13.5 0.6 1.8 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DUF972 PF06156.8 KKK24154.1 - 0.083 13.2 0.2 0.21 11.9 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DUF904 PF06005.7 KKK24154.1 - 0.11 12.7 1.7 0.21 11.9 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF904) TMF_DNA_bd PF12329.3 KKK24154.1 - 0.16 11.8 0.3 0.33 10.7 0.2 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Macoilin PF09726.4 KKK24154.1 - 0.94 7.6 9.8 1.3 7.1 6.8 1.1 1 0 0 1 1 1 0 Transmembrane protein XRCC4 PF06632.7 KKK24154.1 - 1.2 7.8 14.1 1.2 7.8 0.2 2.2 2 0 0 2 2 2 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 Menin PF05053.8 KKK24154.1 - 4.3 5.3 12.2 8.8 4.3 8.4 1.6 1 0 0 1 1 1 0 Menin Slx4 PF09494.5 KKK24155.1 - 4.1e-24 84.1 0.0 7.4e-24 83.2 0.0 1.5 1 0 0 1 1 1 1 Slx4 endonuclease DUF4163 PF13739.1 KKK24155.1 - 0.23 12.2 2.8 8.2 7.2 0.0 3.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4163) DUF1966 PF09260.6 KKK24156.1 - 5.1e-31 106.5 0.0 1e-30 105.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) Alpha-amylase PF00128.19 KKK24156.1 - 0.00019 20.9 0.0 0.00029 20.3 0.0 1.3 1 0 0 1 1 1 1 Alpha amylase, catalytic domain CGI-121 PF08617.5 KKK24157.1 - 1.5e-55 187.2 0.0 1.7e-55 187.0 0.0 1.0 1 0 0 1 1 1 1 Kinase binding protein CGI-121 DUF1227 PF06777.6 KKK24157.1 - 0.097 12.3 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1227) Bax1-I PF01027.15 KKK24158.1 - 6.6e-27 94.4 12.6 1e-26 93.7 8.7 1.3 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 WD40 PF00400.27 KKK24159.1 - 2.1e-25 87.6 18.3 7.1e-10 38.3 0.3 7.4 8 0 0 8 8 8 4 WD domain, G-beta repeat eIF2A PF08662.6 KKK24159.1 - 0.00057 19.6 0.0 0.03 14.0 0.0 2.8 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A zf-rbx1 PF12678.2 KKK24159.1 - 0.045 13.8 7.1 0.055 13.5 0.2 2.6 2 0 0 2 2 2 0 RING-H2 zinc finger Kinesin PF00225.18 KKK24161.1 - 3.3e-115 384.3 0.0 4.8e-115 383.8 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain PMSR PF01625.16 KKK24161.1 - 1.2e-49 168.2 0.0 3.1e-49 166.8 0.0 1.7 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase AAA_33 PF13671.1 KKK24161.1 - 0.0062 16.4 0.3 0.039 13.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain cNMP_binding PF00027.24 KKK24162.1 - 6.7e-38 128.3 0.0 7.8e-21 73.6 0.0 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain LRR_6 PF13516.1 KKK24162.1 - 4.1e-14 51.0 7.4 0.45 10.7 0.1 9.5 10 0 0 10 10 10 3 Leucine Rich repeat LRR_1 PF00560.28 KKK24162.1 - 0.00011 21.7 13.3 13 6.3 0.1 8.9 7 3 2 9 9 9 1 Leucine Rich Repeat F-box-like PF12937.2 KKK24162.1 - 0.00017 21.2 1.8 0.00023 20.7 0.2 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KKK24162.1 - 0.00048 19.7 0.6 0.002 17.7 0.1 2.3 2 0 0 2 2 2 1 F-box domain LRR_8 PF13855.1 KKK24162.1 - 0.00064 19.4 3.4 0.061 13.0 0.2 4.7 6 0 0 6 6 6 1 Leucine rich repeat Cupin_3 PF05899.7 KKK24162.1 - 0.0032 16.8 0.4 0.31 10.4 0.1 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF861) Ste50p-SAM PF09235.5 KKK24162.1 - 0.088 12.8 1.5 4.7 7.3 0.2 3.5 3 1 0 3 3 3 0 Ste50p, sterile alpha motif LRR_7 PF13504.1 KKK24162.1 - 0.32 11.3 16.0 52 4.6 0.1 7.8 9 0 0 9 9 9 0 Leucine rich repeat Tim17 PF02466.14 KKK24163.1 - 0.00016 21.6 1.6 0.00074 19.5 1.2 1.9 1 1 1 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family UCR_Fe-S_N PF10399.4 KKK24163.1 - 0.14 11.3 2.0 0.32 10.2 0.1 2.3 2 0 0 2 2 2 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Dr_adhesin PF12393.3 KKK24163.1 - 0.18 11.9 2.1 0.44 10.7 1.5 1.7 1 0 0 1 1 1 0 Dr family adhesin Alk_phosphatase PF00245.15 KKK24164.1 - 5.5e-110 367.9 0.0 6.8e-110 367.6 0.0 1.1 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.13 KKK24164.1 - 0.002 17.5 0.0 0.0039 16.6 0.0 1.4 1 0 0 1 1 1 1 Metalloenzyme superfamily DUF498 PF04430.9 KKK24164.1 - 0.017 14.6 0.0 0.045 13.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF498/DUF598) DUF754 PF05449.6 KKK24164.1 - 0.11 12.5 0.1 0.2 11.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF754) ABC_tran PF00005.22 KKK24165.1 - 1.2e-33 116.2 0.0 2.9e-33 115.0 0.0 1.7 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 KKK24165.1 - 4.8e-31 108.1 10.9 4.8e-31 108.1 7.5 1.7 2 0 0 2 2 2 1 ABC transporter transmembrane region SMC_N PF02463.14 KKK24165.1 - 4.3e-07 29.3 0.6 1.7e-05 24.1 0.1 2.7 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KKK24165.1 - 8.7e-05 22.6 0.0 0.081 12.8 0.0 2.3 1 1 0 2 2 2 2 AAA domain SbcCD_C PF13558.1 KKK24165.1 - 0.0037 17.1 0.2 0.061 13.2 0.2 2.8 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_16 PF13191.1 KKK24165.1 - 0.0064 16.4 0.5 0.024 14.6 0.0 2.1 2 1 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.1 KKK24165.1 - 0.0086 15.5 0.2 0.021 14.3 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.1 KKK24165.1 - 0.01 15.9 0.1 0.083 13.0 0.1 2.4 1 1 0 1 1 1 0 AAA domain DUF258 PF03193.11 KKK24165.1 - 0.014 14.5 0.0 0.029 13.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_5 PF07728.9 KKK24165.1 - 0.11 12.2 0.1 0.81 9.4 0.0 2.1 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Glyco_hydro_16 PF00722.16 KKK24167.1 - 2.8e-44 150.6 7.3 2.8e-44 150.6 5.0 1.9 2 1 0 2 2 2 1 Glycosyl hydrolases family 16 WAP PF00095.16 KKK24167.1 - 0.0022 17.8 3.2 0.0043 16.9 2.2 1.4 1 0 0 1 1 1 1 WAP-type (Whey Acidic Protein) 'four-disulfide core' Chitin_bind_1 PF00187.14 KKK24167.1 - 0.16 12.0 13.5 0.33 10.9 9.4 1.5 1 0 0 1 1 1 0 Chitin recognition protein SWI-SNF_Ssr4 PF08549.5 KKK24167.1 - 0.23 9.7 0.0 0.23 9.7 0.0 2.0 2 0 0 2 2 2 0 Fungal domain of unknown function (DUF1750) Sugar_tr PF00083.19 KKK24169.1 - 1e-126 423.2 31.3 1.1e-126 423.0 21.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KKK24169.1 - 3.9e-24 85.0 56.2 2.9e-21 75.5 22.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KKK24169.1 - 7.6e-06 24.5 31.8 0.00027 19.4 6.7 3.4 3 1 0 3 3 3 3 MFS/sugar transport protein TPR_19 PF14559.1 KKK24169.1 - 0.16 12.3 0.1 0.25 11.7 0.1 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat MFS_1_like PF12832.2 KKK24169.1 - 0.23 11.2 0.1 0.23 11.2 0.0 4.0 3 1 0 3 3 3 0 MFS_1 like family DUF3154 PF11351.3 KKK24169.1 - 0.25 11.0 1.7 0.42 10.3 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3154) Phage_holin_2 PF04550.7 KKK24169.1 - 0.57 10.3 5.2 0.84 9.7 2.7 2.0 2 0 0 2 2 2 0 Phage holin family 2 Aminotran_5 PF00266.14 KKK24179.1 - 9.3e-21 73.9 0.0 1.5e-20 73.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 KKK24179.1 - 2.3e-06 26.8 0.0 3.5e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II GYF PF02213.11 KKK24180.1 - 2e-18 65.6 0.1 4.6e-18 64.5 0.1 1.7 1 0 0 1 1 1 1 GYF domain Miff PF05644.6 KKK24180.1 - 0.069 12.7 9.4 0.28 10.7 6.5 2.1 1 0 0 1 1 1 0 Mitochondrial and peroxisomal fission factor Mff Med21 PF11221.3 KKK24181.1 - 7.9e-59 197.7 0.0 1e-58 197.3 0.0 1.2 1 0 0 1 1 1 1 Subunit 21 of Mediator complex Med9 PF07544.8 KKK24181.1 - 0.0026 17.4 4.8 0.012 15.3 0.3 2.5 1 1 1 2 2 2 1 RNA polymerase II transcription mediator complex subunit 9 Spore_III_AB PF09548.5 KKK24181.1 - 0.011 15.4 0.5 0.017 14.9 0.1 1.4 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) DUF4455 PF14643.1 KKK24181.1 - 0.093 11.3 0.3 0.12 10.9 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4455) CENP-Q PF13094.1 KKK24181.1 - 0.17 11.9 1.8 0.28 11.2 1.2 1.3 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit ALIX_LYPXL_bnd PF13949.1 KKK24181.1 - 0.17 10.7 1.8 0.25 10.2 1.3 1.2 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV SNF2_N PF00176.18 KKK24182.1 - 5.8e-58 196.0 0.2 8.4e-58 195.5 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KKK24182.1 - 6.7e-11 41.9 0.1 4.4e-08 32.8 0.0 2.7 2 0 0 2 2 2 2 Helicase conserved C-terminal domain DEAD PF00270.24 KKK24182.1 - 7.4e-06 25.5 0.0 1.6e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-RING_5 PF14634.1 KKK24182.1 - 0.0023 17.5 1.1 0.004 16.8 0.8 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 KKK24182.1 - 0.071 12.9 1.3 0.14 11.9 0.9 1.5 1 0 0 1 1 1 0 Ring finger domain HIRAN PF08797.6 KKK24182.1 - 0.11 12.4 0.0 0.23 11.3 0.0 1.6 1 0 0 1 1 1 0 HIRAN domain PI3_PI4_kinase PF00454.22 KKK24183.1 - 6.3e-34 117.4 0.0 1e-33 116.8 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase zf-RING_2 PF13639.1 KKK24184.1 - 3.7e-15 55.4 8.7 3.7e-15 55.4 6.0 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 KKK24184.1 - 1.4e-10 40.6 10.4 4e-09 36.0 3.0 2.2 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KKK24184.1 - 2.4e-08 33.9 4.6 2.4e-08 33.9 3.2 1.8 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 KKK24184.1 - 3.1e-08 33.5 8.2 3.1e-08 33.5 5.7 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KKK24184.1 - 2.6e-06 27.0 7.8 2.6e-06 27.0 5.4 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KKK24184.1 - 1.1e-05 25.0 13.0 1.5e-05 24.5 4.0 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_3 PF14369.1 KKK24184.1 - 0.00028 20.7 6.4 0.0085 16.0 2.0 2.7 2 0 0 2 2 2 1 zinc-finger zf-Apc11 PF12861.2 KKK24184.1 - 0.00082 19.1 3.3 0.00082 19.1 2.3 1.8 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger HypA PF01155.14 KKK24184.1 - 0.0016 18.1 5.7 0.0032 17.1 0.2 2.2 2 0 0 2 2 2 1 Hydrogenase expression/synthesis hypA family Baculo_RING PF05883.6 KKK24184.1 - 0.048 13.4 0.9 0.048 13.4 0.6 1.8 2 0 0 2 2 2 0 Baculovirus U-box/Ring-like domain zf-RING_4 PF14570.1 KKK24184.1 - 0.35 10.4 12.7 0.069 12.7 2.9 2.4 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain DZR PF12773.2 KKK24184.1 - 0.5 10.2 7.6 2.4 8.0 0.2 2.5 2 1 0 2 2 2 0 Double zinc ribbon PHD PF00628.24 KKK24184.1 - 0.64 9.7 14.2 0.11 12.1 5.0 2.4 2 0 0 2 2 2 0 PHD-finger FANCL_C PF11793.3 KKK24184.1 - 1.4 8.8 9.5 1 9.3 4.2 2.4 2 1 0 2 2 2 0 FANCL C-terminal domain zf-RING_UBOX PF13445.1 KKK24184.1 - 1.6 8.5 5.6 3.7 7.3 3.9 1.6 1 0 0 1 1 1 0 RING-type zinc-finger Prok-RING_1 PF14446.1 KKK24184.1 - 2.2 8.0 11.5 12 5.7 3.7 2.8 2 1 0 2 2 2 0 Prokaryotic RING finger family 1 UPF0547 PF10571.4 KKK24184.1 - 2.3 7.9 9.9 3.8 7.2 0.2 3.4 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 zinc-ribbons_6 PF07191.7 KKK24184.1 - 4.8 7.0 7.5 7.2 6.4 0.1 3.0 2 1 1 3 3 3 0 zinc-ribbons zf-ribbon_3 PF13248.1 KKK24184.1 - 6.1 6.1 6.5 30 3.9 0.0 3.0 2 1 1 3 3 3 0 zinc-ribbon domain Spc24 PF08286.6 KKK24185.1 - 2e-38 130.6 0.6 3.5e-37 126.6 0.0 2.1 2 0 0 2 2 2 1 Spc24 subunit of Ndc80 Streptin-Immun PF11083.3 KKK24185.1 - 0.016 15.1 0.3 0.11 12.4 0.0 2.0 2 0 0 2 2 2 0 Lantibiotic streptin immunity protein WXG100 PF06013.7 KKK24185.1 - 0.16 12.0 1.7 0.84 9.6 0.0 2.5 3 0 0 3 3 3 0 Proteins of 100 residues with WXG APG6 PF04111.7 KKK24185.1 - 0.23 10.4 5.7 0.3 10.0 3.9 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Prefoldin_2 PF01920.15 KKK24185.1 - 0.23 11.2 6.8 1.3 8.8 0.6 2.2 2 0 0 2 2 2 0 Prefoldin subunit DUF4613 PF15390.1 KKK24185.1 - 0.36 8.9 2.2 0.43 8.7 1.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) DMPK_coil PF08826.5 KKK24185.1 - 0.42 10.5 9.6 0.35 10.8 0.6 2.2 2 0 0 2 2 2 0 DMPK coiled coil domain like HR1 PF02185.11 KKK24185.1 - 0.6 9.8 7.2 0.66 9.7 0.5 2.3 2 0 0 2 2 2 0 Hr1 repeat Viral_P18 PF04521.8 KKK24185.1 - 0.91 8.9 6.6 0.32 10.4 0.8 2.2 1 1 1 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein Lge1 PF11488.3 KKK24185.1 - 5.9 7.1 6.5 2.5 8.3 0.7 2.2 1 1 1 2 2 2 0 Transcriptional regulatory protein LGE1 TMF_DNA_bd PF12329.3 KKK24185.1 - 7.7 6.4 9.9 7.3 6.4 1.8 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Fis1_TPR_C PF14853.1 KKK24186.1 - 2e-24 85.2 0.5 3.2e-24 84.5 0.3 1.4 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.1 KKK24186.1 - 2.1e-17 62.0 0.0 3.7e-17 61.3 0.0 1.4 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_16 PF13432.1 KKK24186.1 - 0.00055 20.5 0.2 0.00095 19.7 0.1 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.12 KKK24186.1 - 0.0066 16.2 1.1 0.0066 16.2 0.8 1.8 2 0 0 2 2 2 1 Tetratricopeptide repeat DUF357 PF04010.8 KKK24186.1 - 0.064 12.9 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF357) Sugar_tr PF00083.19 KKK24209.1 - 8.3e-91 304.8 23.1 1.1e-90 304.3 16.0 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KKK24209.1 - 6.6e-15 54.6 39.9 7.6e-09 34.7 7.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Capsid_NCLDV PF04451.7 KKK24210.1 - 0.061 12.3 0.1 0.13 11.2 0.1 1.4 1 0 0 1 1 1 0 Large eukaryotic DNA virus major capsid protein PGM_PMM_I PF02878.11 KKK24211.1 - 5.2e-32 110.2 0.1 1e-31 109.2 0.1 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.11 KKK24211.1 - 5.1e-25 87.7 0.0 1.1e-24 86.5 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III RNase_T PF00929.19 KKK24211.1 - 3.3e-19 69.7 0.0 7.1e-19 68.6 0.0 1.5 1 0 0 1 1 1 1 Exonuclease PGM_PMM_II PF02879.11 KKK24211.1 - 2e-14 53.7 0.0 4.5e-14 52.6 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 KKK24211.1 - 2.5e-09 37.0 0.0 5.8e-09 35.8 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain GFO_IDH_MocA PF01408.17 KKK24212.1 - 1.1e-07 32.3 0.0 2.2e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Ilar_coat PF01787.11 KKK24212.1 - 0.081 12.4 0.1 0.16 11.5 0.1 1.5 1 0 0 1 1 1 0 Ilarvirus coat protein DUF515 PF04415.7 KKK24212.1 - 9.1 4.4 7.0 13 3.8 4.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) AICARFT_IMPCHas PF01808.13 KKK24217.1 - 1.6e-110 369.0 0.0 2.3e-110 368.6 0.0 1.2 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.17 KKK24217.1 - 3.8e-25 87.6 0.0 7.6e-25 86.6 0.0 1.6 1 0 0 1 1 1 1 MGS-like domain NUDIX PF00293.23 KKK24265.1 - 6.4e-13 48.5 0.0 1.4e-12 47.4 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain CBFD_NFYB_HMF PF00808.18 KKK24265.1 - 0.00098 19.1 0.0 0.002 18.1 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Frag1 PF10277.4 KKK24266.1 - 1.6e-11 44.1 0.0 2.7e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family Trypan_PARP PF05887.6 KKK24266.1 - 8.8e-06 25.5 11.2 1.9e-05 24.5 7.8 1.5 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) DUF4366 PF14283.1 KKK24266.1 - 0.27 10.6 1.2 0.73 9.2 0.8 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) DSBA PF01323.15 KKK24267.1 - 3.3e-31 108.3 0.0 8e-15 54.8 0.0 2.0 2 0 0 2 2 2 2 DSBA-like thioredoxin domain Sod_Fe_C PF02777.13 KKK24268.1 - 1.4e-13 50.5 0.5 2.1e-07 30.7 0.8 2.2 1 1 1 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 KKK24268.1 - 0.028 14.6 0.1 0.054 13.7 0.0 1.5 1 0 0 1 1 1 0 Iron/manganese superoxide dismutases, alpha-hairpin domain DAD PF02109.11 KKK24269.1 - 0.027 14.5 0.0 0.049 13.7 0.0 1.4 1 0 0 1 1 1 0 DAD family Macoilin PF09726.4 KKK24269.1 - 0.24 9.6 4.5 0.25 9.5 3.1 1.1 1 0 0 1 1 1 0 Transmembrane protein FMN_dh PF01070.13 KKK24270.1 - 7.2e-105 350.7 0.1 1.2e-104 349.9 0.1 1.3 1 1 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 KKK24270.1 - 1.1e-21 76.4 0.0 4.5e-21 74.4 0.0 2.0 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 KKK24270.1 - 2.3e-06 26.7 0.0 3.7e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 KKK24270.1 - 2.4e-06 26.7 0.0 0.00027 19.9 0.0 2.4 3 0 0 3 3 3 2 IMP dehydrogenase / GMP reductase domain ATP11 PF06644.6 KKK24270.1 - 0.014 14.9 0.0 0.02 14.3 0.0 1.2 1 0 0 1 1 1 0 ATP11 protein His_biosynth PF00977.16 KKK24270.1 - 0.015 14.5 0.0 0.036 13.3 0.0 1.5 1 0 0 1 1 1 0 Histidine biosynthesis protein NMO PF03060.10 KKK24270.1 - 0.052 12.6 0.2 0.11 11.6 0.1 1.5 1 0 0 1 1 1 0 Nitronate monooxygenase Fungal_trans PF04082.13 KKK24271.1 - 3.1e-22 78.7 0.1 8.6e-22 77.2 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Polyketide_cyc PF03364.15 KKK24271.1 - 5.9e-17 61.8 0.0 1.5e-16 60.5 0.0 1.7 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport VTC PF09359.5 KKK24272.1 - 4.3e-90 301.5 0.0 7.5e-90 300.7 0.0 1.4 1 0 0 1 1 1 1 VTC domain SPX PF03105.14 KKK24272.1 - 1.3e-17 64.5 13.9 2.9e-12 46.9 0.5 4.2 2 2 1 3 3 3 2 SPX domain DUF202 PF02656.10 KKK24272.1 - 2e-09 37.5 5.3 5e-09 36.2 2.9 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF3815 PF12821.2 KKK24272.1 - 0.1 12.5 0.1 0.16 11.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3815) 6PF2K PF01591.13 KKK24273.1 - 5.1e-68 228.4 0.0 4.5e-48 163.2 0.0 2.2 2 0 0 2 2 2 2 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 KKK24273.1 - 3.8e-28 98.5 0.0 9.6e-28 97.2 0.0 1.7 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 KKK24273.1 - 2e-06 27.7 0.0 0.0093 15.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 KKK24273.1 - 0.0018 19.0 0.0 0.006 17.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain KTI12 PF08433.5 KKK24273.1 - 0.045 12.9 0.0 0.086 12.0 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Zeta_toxin PF06414.7 KKK24273.1 - 0.16 11.0 0.1 2.1 7.3 0.0 2.5 3 0 0 3 3 3 0 Zeta toxin DUF998 PF06197.8 KKK24274.1 - 0.0019 17.5 4.1 0.037 13.3 1.9 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF998) DUF202 PF02656.10 KKK24274.1 - 0.0026 17.9 6.9 0.02 15.1 4.8 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF202) RseC_MucC PF04246.7 KKK24274.1 - 0.15 11.5 0.9 0.24 10.9 0.0 1.7 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC APG17 PF04108.7 KKK24275.1 - 0.049 12.4 6.6 0.075 11.8 4.6 1.2 1 0 0 1 1 1 0 Autophagy protein Apg17 Complex1_LYR_2 PF13233.1 KKK24275.1 - 0.35 11.3 3.3 0.72 10.3 2.3 1.6 1 0 0 1 1 1 0 Complex1_LYR-like TBPIP PF07106.8 KKK24275.1 - 0.57 9.7 10.6 1.9 7.9 5.7 2.5 2 1 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) PIG-S PF10510.4 KKK24276.1 - 1e-180 601.8 0.3 1e-180 601.8 0.2 1.5 2 0 0 2 2 2 1 Phosphatidylinositol-glycan biosynthesis class S protein FimP PF09766.4 KKK24276.1 - 1.5e-23 83.4 16.5 1.5e-23 83.4 11.5 1.5 2 0 0 2 2 2 1 Fms-interacting protein DUF4200 PF13863.1 KKK24276.1 - 0.0071 16.2 16.3 0.15 11.9 0.7 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4200) DUF972 PF06156.8 KKK24276.1 - 0.11 12.8 9.4 4.8 7.5 3.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Cob_adeno_trans PF01923.13 KKK24276.1 - 1.5 8.5 7.9 0.26 11.0 0.1 2.8 3 0 0 3 3 3 0 Cobalamin adenosyltransferase DUF349 PF03993.7 KKK24276.1 - 2.8 8.1 9.7 24 5.2 3.5 2.7 1 1 1 2 2 2 0 Domain of Unknown Function (DUF349) Pkinase PF00069.20 KKK24278.1 - 8.1e-05 21.8 0.0 9.9e-05 21.6 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 KKK24278.1 - 0.0022 17.0 0.0 0.0032 16.5 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3016 PF11454.3 KKK24278.1 - 0.15 11.6 0.0 0.25 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3016) Phos_pyr_kin PF08543.7 KKK24279.1 - 5e-12 45.5 0.0 1.1e-11 44.3 0.0 1.7 1 1 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.19 KKK24279.1 - 1.7e-08 33.9 2.6 4.5e-07 29.3 1.8 2.5 1 1 0 1 1 1 1 pfkB family carbohydrate kinase Afi1 PF07792.7 KKK24282.1 - 1.8e-64 216.1 0.1 3.1e-64 215.3 0.1 1.4 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking SPA PF08616.5 KKK24282.1 - 1.9e-37 127.3 0.0 3.2e-37 126.6 0.0 1.4 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.4 KKK24282.1 - 1.3e-08 33.8 0.4 0.0094 14.4 0.0 3.6 3 1 1 4 4 4 3 Transport protein Avl9 DUF2347 PF09804.4 KKK24282.1 - 0.021 14.1 0.0 0.068 12.4 0.0 1.9 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) HNF-1_N PF04814.8 KKK24282.1 - 0.062 13.3 1.1 1.2 9.2 1.1 2.3 2 0 0 2 2 2 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus Peripla_BP_6 PF13458.1 KKK24282.1 - 0.12 11.6 0.0 0.21 10.9 0.0 1.2 1 0 0 1 1 1 0 Periplasmic binding protein RabGAP-TBC PF00566.13 KKK24283.1 - 1.3e-29 103.1 0.0 1.3e-24 86.8 0.0 2.2 2 0 0 2 2 2 2 Rab-GTPase-TBC domain EF-hand_6 PF13405.1 KKK24283.1 - 8e-12 43.9 2.7 1.9e-05 24.1 0.2 3.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 KKK24283.1 - 8e-12 43.5 2.7 1.4e-05 24.0 0.5 2.8 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 KKK24283.1 - 1.5e-10 41.0 1.0 1e-08 35.1 0.1 2.3 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 KKK24283.1 - 1e-06 27.7 10.6 0.0026 17.0 0.2 3.1 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.1 KKK24283.1 - 7.9e-06 25.4 0.2 0.13 11.9 0.1 2.9 2 0 0 2 2 2 2 EF-hand domain pair RRM_1 PF00076.17 KKK24284.1 - 1.6e-18 66.0 0.0 2.9e-14 52.4 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KKK24284.1 - 4.3e-15 55.4 0.0 4.1e-14 52.3 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KKK24284.1 - 0.00058 19.6 0.0 0.0011 18.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Glyco_hydro_18 PF00704.23 KKK24285.1 - 1.3e-73 248.4 5.2 2.1e-73 247.7 3.6 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.14 KKK24285.1 - 4.3e-11 42.6 15.4 4.3e-11 42.6 10.7 6.1 6 2 2 8 8 8 2 Chitin recognition protein Ank_2 PF12796.2 KKK24286.1 - 2.1e-31 108.0 0.0 7.4e-12 45.4 0.0 3.9 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 KKK24286.1 - 5.8e-22 76.3 4.7 0.0011 18.6 0.2 8.1 8 0 0 8 8 8 4 Ankyrin repeat Ank_3 PF13606.1 KKK24286.1 - 5.3e-20 69.5 0.6 0.012 15.7 0.1 8.1 8 0 0 8 8 8 4 Ankyrin repeat Ank_4 PF13637.1 KKK24286.1 - 2.6e-17 62.8 3.5 6.4e-06 26.5 0.0 6.7 3 2 4 7 7 7 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 KKK24286.1 - 8.1e-13 48.1 4.0 0.036 14.3 0.0 7.4 3 2 5 8 8 8 4 Ankyrin repeats (many copies) APH PF01636.18 KKK24287.1 - 3e-34 118.7 0.0 1.6e-32 113.1 0.0 2.4 2 1 0 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.15 KKK24287.1 - 9.1e-06 25.0 0.1 1.6e-05 24.2 0.0 1.4 1 1 0 1 1 1 1 Ecdysteroid kinase RIO1 PF01163.17 KKK24287.1 - 0.001 18.4 0.0 0.16 11.3 0.0 2.4 2 1 0 2 2 2 2 RIO1 family Choline_kinase PF01633.15 KKK24287.1 - 0.0016 18.0 0.0 0.0029 17.2 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Fructosamin_kin PF03881.9 KKK24287.1 - 0.0044 16.0 0.0 1.2 8.0 0.0 2.5 2 1 0 2 2 2 2 Fructosamine kinase DUF1679 PF07914.6 KKK24287.1 - 0.029 13.0 0.0 0.9 8.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) DPM2 PF07297.7 KKK24288.1 - 5e-35 119.6 1.6 5.8e-35 119.4 1.1 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) DUF4083 PF13314.1 KKK24288.1 - 0.00018 21.2 0.2 0.00018 21.2 0.1 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4083) PIG-P PF08510.7 KKK24288.1 - 0.0086 15.7 1.4 0.011 15.4 0.9 1.1 1 0 0 1 1 1 1 PIG-P DUF4229 PF14012.1 KKK24288.1 - 0.27 11.1 3.0 0.39 10.6 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4229) FixQ PF05545.6 KKK24288.1 - 0.96 9.1 4.8 13 5.5 2.0 2.4 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ DUF1469 PF07332.6 KKK24288.1 - 1.5 8.5 6.3 2.5 7.8 4.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1469) MA3 PF02847.12 KKK24289.1 - 5.8e-26 90.4 0.0 1.9e-25 88.7 0.0 1.9 2 0 0 2 2 2 1 MA3 domain MIF4G PF02854.14 KKK24289.1 - 1.6e-25 89.7 0.9 2.2e-25 89.2 0.2 1.6 2 0 0 2 2 2 1 MIF4G domain WD40 PF00400.27 KKK24290.1 - 3.1e-22 77.5 11.8 3.4e-07 29.8 0.1 7.1 7 0 0 7 7 7 5 WD domain, G-beta repeat SET PF00856.23 KKK24290.1 - 0.00092 19.5 1.6 0.11 12.7 0.0 3.4 4 0 0 4 4 4 1 SET domain TPR_9 PF13371.1 KKK24290.1 - 0.051 13.4 1.5 0.11 12.3 0.4 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.1 KKK24290.1 - 0.19 11.3 0.2 0.44 10.2 0.2 1.5 1 0 0 1 1 1 0 TPR repeat Glucosamine_iso PF01182.15 KKK24292.1 - 2.7e-58 196.9 0.0 3.2e-58 196.7 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Zn_ribbon_recom PF13408.1 KKK24293.1 - 0.13 12.4 0.9 0.26 11.5 0.6 1.4 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain zf-FPG_IleRS PF06827.9 KKK24293.1 - 1.3 8.7 0.0 1.3 8.7 0.0 2.4 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS Myb_DNA-binding PF00249.26 KKK24294.1 - 1.7e-09 37.5 0.0 2.3e-06 27.5 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain DUF1777 PF08648.7 KKK24294.1 - 0.034 13.8 72.4 0.0062 16.2 8.0 4.0 3 1 0 3 3 3 0 Protein of unknown function (DUF1777) p450 PF00067.17 KKK24295.1 - 1.1e-61 208.7 0.0 1.3e-61 208.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Aa_trans PF01490.13 KKK24296.1 - 3.7e-53 180.4 37.4 4.2e-53 180.2 25.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Dispanin PF04505.7 KKK24296.1 - 0.078 12.5 0.4 0.078 12.5 0.3 2.2 2 0 0 2 2 2 0 Interferon-induced transmembrane protein HMG-CoA_red PF00368.13 KKK24297.1 - 6.3e-150 498.9 6.4 8e-150 498.6 4.4 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase HPIH PF13323.1 KKK24297.1 - 8.3e-36 122.9 0.1 1.5e-35 122.1 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain with HPIH motif Sterol-sensing PF12349.3 KKK24297.1 - 1.7e-15 56.8 1.4 4.5e-07 29.4 0.0 3.0 2 1 1 3 3 3 2 Sterol-sensing domain of SREBP cleavage-activation SKG6 PF08693.5 KKK24301.1 - 3e-06 26.4 4.9 3e-06 26.4 3.4 3.3 3 0 0 3 3 3 1 Transmembrane alpha-helix domain DcuC PF03606.10 KKK24301.1 - 0.0023 16.2 0.0 0.0035 15.6 0.0 1.2 1 0 0 1 1 1 1 C4-dicarboxylate anaerobic carrier DUF3609 PF12259.3 KKK24301.1 - 0.016 13.8 0.0 0.026 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3609) Rifin_STEVOR PF02009.11 KKK24301.1 - 0.032 13.8 14.6 0.81 9.2 10.1 2.2 1 1 0 1 1 1 0 Rifin/stevor family Gemini_mov PF01708.11 KKK24301.1 - 0.57 9.7 0.0 0.57 9.7 0.0 2.4 2 1 0 2 2 2 0 Geminivirus putative movement protein DUF1510 PF07423.6 KKK24301.1 - 0.78 9.0 0.0 0.78 9.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) Mitofilin PF09731.4 KKK24301.1 - 4.1 5.9 10.3 5.8 5.4 7.1 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein MFS_1 PF07690.11 KKK24302.1 - 2.6e-43 148.1 30.5 2.6e-43 148.1 21.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KKK24302.1 - 1e-13 50.7 9.2 1e-13 50.7 6.4 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter DNA_primase_S PF01896.14 KKK24305.1 - 1.3e-53 180.7 0.0 2.3e-53 179.9 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase small subunit COesterase PF00135.23 KKK24306.1 - 3.1e-62 211.0 0.0 8.2e-62 209.6 0.0 1.6 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KKK24306.1 - 1.6e-11 44.1 0.0 5.6e-11 42.4 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KKK24306.1 - 0.00031 20.4 0.1 0.00057 19.6 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KKK24306.1 - 0.047 12.8 0.0 0.087 12.0 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Fig1 PF12351.3 KKK24307.1 - 1.7e-58 197.4 6.8 1.7e-58 197.4 4.7 2.0 2 0 0 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 SUR7 PF06687.7 KKK24307.1 - 6.2e-09 35.7 11.9 1.2e-08 34.7 8.2 1.4 1 1 0 1 1 1 1 SUR7/PalI family DUF898 PF05987.8 KKK24307.1 - 4.3e-05 22.5 6.0 4.3e-05 22.5 4.1 1.7 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF898) SAM_adeno_trans PF01887.11 KKK24307.1 - 0.076 12.0 0.1 0.11 11.5 0.1 1.1 1 0 0 1 1 1 0 S-adenosyl-l-methionine hydroxide adenosyltransferase Amastin PF07344.6 KKK24307.1 - 5 6.7 9.0 0.93 9.0 3.2 1.9 2 0 0 2 2 2 0 Amastin surface glycoprotein DUF4064 PF13273.1 KKK24307.1 - 5.2 7.2 17.0 1.4 9.1 0.6 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF4064) XPG_I PF00867.13 KKK24308.1 - 9.1e-27 92.9 0.3 2.3e-26 91.6 0.1 1.8 2 0 0 2 2 2 1 XPG I-region XPG_N PF00752.12 KKK24308.1 - 1.9e-23 82.6 0.0 4.9e-23 81.3 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.2 KKK24308.1 - 0.00034 20.1 0.0 0.00061 19.3 0.0 1.4 1 0 0 1 1 1 1 XPG domain containing HTH_13 PF11972.3 KKK24308.1 - 0.13 12.1 0.3 4.6 7.1 0.0 2.7 3 0 0 3 3 3 0 HTH DNA binding domain TPR_2 PF07719.12 KKK24308.1 - 0.14 12.1 0.0 0.4 10.7 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_11 PF13414.1 KKK24308.1 - 0.15 11.7 0.0 0.34 10.5 0.0 1.5 1 0 0 1 1 1 0 TPR repeat DUF2962 PF11176.3 KKK24309.1 - 1.4e-47 161.1 0.2 3.4e-47 159.8 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2962) MAM33 PF02330.11 KKK24309.1 - 1.1e-35 123.2 2.6 8.2e-35 120.4 1.8 2.1 1 1 0 1 1 1 1 Mitochondrial glycoprotein NPV_P10 PF05531.7 KKK24309.1 - 0.09 13.0 0.2 0.34 11.1 0.0 2.0 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Cactin_mid PF10312.4 KKK24311.1 - 9.3e-64 214.2 4.0 1.5e-63 213.5 2.8 1.3 1 0 0 1 1 1 1 Conserved mid region of cactin CactinC_cactus PF09732.4 KKK24311.1 - 2e-56 188.9 4.8 9.6e-56 186.7 3.9 1.7 2 0 0 2 2 2 1 Cactus-binding C-terminus of cactin protein XLF PF09302.6 KKK24312.1 - 3.2e-35 121.4 1.2 3.2e-35 121.4 0.8 1.5 2 0 0 2 2 2 1 XLF (XRCC4-like factor) Fork_head PF00250.13 KKK24313.1 - 1.1e-16 60.6 0.1 2e-16 59.7 0.0 1.3 1 0 0 1 1 1 1 Fork head domain Pacs-1 PF10254.4 KKK24313.1 - 0.27 9.8 1.4 2.8 6.4 0.0 2.0 1 1 1 2 2 2 0 PACS-1 cytosolic sorting protein SKN1 PF03935.10 KKK24335.1 - 4e-228 757.6 2.5 4.8e-228 757.3 1.8 1.1 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) zf-RING_2 PF13639.1 KKK24346.1 - 2.8e-13 49.4 5.2 5e-13 48.6 3.6 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 KKK24346.1 - 7.9e-07 28.9 4.7 1.4e-06 28.2 3.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KKK24346.1 - 8.9e-06 25.2 3.6 1.5e-05 24.5 2.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KKK24346.1 - 1.3e-05 24.7 3.0 2.2e-05 24.0 2.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 KKK24346.1 - 1.4e-05 25.0 0.3 2.9e-05 24.0 0.2 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 KKK24346.1 - 1.7e-05 24.3 2.8 2.8e-05 23.7 2.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) TMEM154 PF15102.1 KKK24346.1 - 0.002 17.8 1.5 0.0088 15.7 0.0 2.2 2 0 0 2 2 2 1 TMEM154 protein family zf-RING_UBOX PF13445.1 KKK24346.1 - 0.032 13.9 0.8 0.089 12.5 0.2 2.1 1 1 0 1 1 1 0 RING-type zinc-finger DUF4389 PF14333.1 KKK24346.1 - 0.038 13.6 0.2 0.073 12.7 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4389) BPD_transp_1 PF00528.17 KKK24346.1 - 0.04 13.4 0.0 0.056 12.9 0.0 1.2 1 0 0 1 1 1 0 Binding-protein-dependent transport system inner membrane component zf-Apc11 PF12861.2 KKK24346.1 - 0.065 13.0 1.1 0.16 11.8 0.8 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger PHD PF00628.24 KKK24346.1 - 0.084 12.5 2.9 0.16 11.6 2.0 1.5 1 0 0 1 1 1 0 PHD-finger PgaD PF13994.1 KKK24346.1 - 0.12 11.8 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 PgaD-like protein zf-C3HC4_4 PF15227.1 KKK24346.1 - 0.21 11.4 4.1 0.58 10.0 2.8 1.8 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING DUF912 PF06024.7 KKK24346.1 - 0.22 11.5 0.5 0.69 9.9 0.0 1.9 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Prok-RING_1 PF14446.1 KKK24346.1 - 0.24 11.1 3.9 0.25 11.1 0.5 2.1 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 zf-RING-like PF08746.6 KKK24346.1 - 0.78 9.7 2.7 1.5 8.9 1.9 1.5 1 0 0 1 1 1 0 RING-like domain FRG1 PF06229.7 KKK24347.1 - 6.2e-62 208.4 0.2 1.2e-61 207.5 0.1 1.5 1 1 0 1 1 1 1 FRG1-like family Spore_YtfJ PF09579.5 KKK24347.1 - 1.7 8.5 6.5 3 7.7 4.5 1.4 1 0 0 1 1 1 0 Sporulation protein YtfJ (Spore_YtfJ) ADH_N PF08240.7 KKK24348.1 - 4.5e-36 122.9 2.3 5.4e-35 119.4 1.8 2.2 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KKK24348.1 - 4.8e-15 55.2 0.0 7.6e-15 54.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_7 PF13241.1 KKK24348.1 - 0.0027 17.9 0.0 0.005 17.0 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding ADH_zinc_N_2 PF13602.1 KKK24348.1 - 0.0046 17.8 0.0 0.0085 16.9 0.0 1.5 1 1 0 1 1 1 1 Zinc-binding dehydrogenase FAD_binding_3 PF01494.14 KKK24348.1 - 0.012 14.7 0.4 0.018 14.0 0.3 1.2 1 0 0 1 1 1 0 FAD binding domain Gp_dh_N PF00044.19 KKK24348.1 - 0.046 13.6 0.0 0.091 12.7 0.0 1.4 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DUF2318 PF10080.4 KKK24348.1 - 0.093 12.5 0.4 5.9 6.7 0.1 2.6 2 0 0 2 2 2 0 Predicted membrane protein (DUF2318) XdhC_C PF13478.1 KKK24348.1 - 0.1 12.9 0.0 0.16 12.3 0.0 1.3 1 0 0 1 1 1 0 XdhC Rossmann domain HECT PF00632.20 KKK24349.1 - 9.9e-76 254.8 0.0 1.4e-75 254.4 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) pKID PF02173.12 KKK24349.1 - 0.15 11.2 0.0 3.2 7.0 0.0 2.4 2 0 0 2 2 2 0 pKID domain cwf21 PF08312.7 KKK24349.1 - 0.51 10.2 2.2 0.74 9.7 0.6 2.0 2 0 0 2 2 2 0 cwf21 domain C1_1 PF00130.17 KKK24350.1 - 0.19 11.4 1.2 0.37 10.5 0.9 1.4 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) OrfB_Zn_ribbon PF07282.6 KKK24350.1 - 0.22 11.1 0.6 0.48 10.1 0.4 1.5 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Ribosomal_L15e PF00827.12 KKK24351.1 - 5.3e-90 300.0 12.2 6.1e-90 299.8 8.4 1.0 1 0 0 1 1 1 1 Ribosomal L15 PSP1 PF04468.7 KKK24352.1 - 1.5e-30 104.9 1.3 2.9e-30 104.0 0.9 1.5 1 0 0 1 1 1 1 PSP1 C-terminal conserved region Rotavirus_VP3 PF06929.6 KKK24352.1 - 0.26 9.1 0.2 0.38 8.5 0.2 1.1 1 0 0 1 1 1 0 Rotavirus VP3 protein Nfu_N PF08712.6 KKK24353.1 - 1.1e-29 101.8 0.0 3.2e-29 100.3 0.0 1.8 2 0 0 2 2 2 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.12 KKK24353.1 - 1.8e-22 78.8 0.1 2.8e-22 78.2 0.1 1.3 1 0 0 1 1 1 1 NifU-like domain NPR2 PF06218.6 KKK24354.1 - 2.7e-135 451.4 0.0 5.6e-135 450.3 0.0 1.5 2 0 0 2 2 2 1 Nitrogen permease regulator 2 LRR19-TM PF15176.1 KKK24354.1 - 0.03 14.0 4.8 0.079 12.6 3.3 1.7 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain Afi1 PF07792.7 KKK24354.1 - 0.18 11.7 1.9 0.25 11.3 0.0 2.0 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Zip PF02535.17 KKK24354.1 - 0.25 10.3 4.8 0.38 9.7 3.3 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter BAF1_ABF1 PF04684.8 KKK24354.1 - 2.7 6.7 11.6 4 6.1 8.0 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Ada3 PF10198.4 KKK24355.1 - 2e-45 153.7 0.1 4.7e-45 152.5 0.1 1.7 1 0 0 1 1 1 1 Histone acetyltransferases subunit 3 tRNA-synt_2 PF00152.15 KKK24356.1 - 3.8e-78 262.6 0.0 4.3e-78 262.4 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.15 KKK24356.1 - 5.3e-08 32.3 0.1 5.6e-05 22.4 0.0 2.5 3 0 0 3 3 3 2 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 KKK24356.1 - 0.00051 19.6 0.1 0.73 9.4 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) tRNA_anti-codon PF01336.20 KKK24356.1 - 0.006 16.4 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain zf-Tim10_DDP PF02953.10 KKK24357.1 - 4.1e-26 90.0 1.2 4.8e-26 89.8 0.9 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger ABC_membrane_2 PF06472.10 KKK24358.1 - 1.3e-90 303.3 0.0 2.1e-90 302.6 0.0 1.4 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 Clr2 PF10383.4 KKK24358.1 - 1.3e-35 122.4 0.1 2.6e-35 121.4 0.0 1.6 1 0 0 1 1 1 1 Transcription-silencing protein Clr2 ABC_tran PF00005.22 KKK24358.1 - 2.3e-12 47.3 0.0 4.8e-12 46.3 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_23 PF13476.1 KKK24358.1 - 0.0096 16.2 0.6 2.2 8.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 KKK24358.1 - 0.045 12.7 0.0 0.12 11.4 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_29 PF13555.1 KKK24358.1 - 0.054 13.0 0.0 0.27 10.7 0.0 2.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_16 PF13191.1 KKK24358.1 - 0.059 13.3 0.1 0.14 12.1 0.1 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA PF00004.24 KKK24358.1 - 0.11 12.6 0.5 0.27 11.4 0.0 1.9 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) PgaD PF13994.1 KKK24358.1 - 0.19 11.1 0.0 0.45 9.9 0.0 1.6 1 0 0 1 1 1 0 PgaD-like protein AAA_22 PF13401.1 KKK24358.1 - 0.2 11.7 0.2 1.4 9.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.16 KKK24358.1 - 0.26 10.4 0.0 0.44 9.6 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI 2OG-FeII_Oxy PF03171.15 KKK24359.1 - 0.07 13.4 0.0 0.17 12.1 0.0 1.8 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily NAD_binding_1 PF00175.16 KKK24360.1 - 7.2e-33 113.4 0.0 1.2e-32 112.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 KKK24360.1 - 2.3e-20 72.5 0.0 6e-20 71.2 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 KKK24360.1 - 2.5e-08 33.9 0.0 0.00039 20.3 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain Ribosomal_L18ae PF01775.12 KKK24361.1 - 2.9e-60 201.5 0.3 3.7e-60 201.2 0.2 1.1 1 0 0 1 1 1 1 Ribosomal L18ae/LX protein domain PCI PF01399.22 KKK24362.1 - 3.9e-09 36.7 0.0 8.5e-09 35.6 0.0 1.6 1 0 0 1 1 1 1 PCI domain DUF433 PF04255.9 KKK24362.1 - 0.013 14.9 0.0 0.031 13.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF433) BTB PF00651.26 KKK24363.1 - 1.2e-05 25.2 0.1 7.8e-05 22.6 0.0 2.3 3 0 0 3 3 3 1 BTB/POZ domain Lactamase_B_2 PF12706.2 KKK24365.1 - 7.9e-12 45.1 0.0 1.8e-11 43.9 0.0 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 KKK24365.1 - 0.00028 20.6 0.0 0.00069 19.3 0.0 1.7 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily DRMBL PF07522.9 KKK24365.1 - 0.0004 20.3 0.0 0.0014 18.6 0.0 1.9 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Amidohydro_1 PF01979.15 KKK24366.1 - 1.9e-62 211.8 4.3 2.7e-62 211.3 3.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.15 KKK24366.1 - 2.5e-56 189.0 0.7 4.9e-56 188.0 0.5 1.5 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Urease_beta PF00699.15 KKK24366.1 - 1.2e-41 140.6 0.2 3.6e-41 139.0 0.0 1.9 2 0 0 2 2 2 1 Urease beta subunit Urease_gamma PF00547.13 KKK24366.1 - 1.4e-37 127.6 0.1 4.4e-37 126.0 0.0 1.9 2 0 0 2 2 2 1 Urease, gamma subunit Amidohydro_5 PF13594.1 KKK24366.1 - 4.9e-07 29.4 3.1 1.6e-06 27.8 2.1 1.9 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 KKK24366.1 - 2e-05 23.9 2.3 5.2e-05 22.6 0.1 2.3 1 1 1 2 2 2 1 Amidohydrolase family HMG_box PF00505.14 KKK24367.1 - 8.1e-11 42.0 1.7 8.1e-11 42.0 1.2 2.6 3 0 0 3 3 3 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KKK24367.1 - 5.5e-05 23.4 0.8 5.5e-05 23.4 0.5 3.2 3 1 0 3 3 3 1 HMG-box domain POTRA_2 PF08479.6 KKK24367.1 - 0.0043 16.6 0.2 0.079 12.6 0.0 2.3 1 1 1 2 2 2 1 POTRA domain, ShlB-type FixO PF02433.10 KKK24367.1 - 0.28 10.5 3.1 0.49 9.7 2.2 1.4 1 0 0 1 1 1 0 Cytochrome C oxidase, mono-heme subunit/FixO DUF4551 PF15087.1 KKK24367.1 - 3.7 5.7 10.2 5.2 5.3 7.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) CLTH PF10607.4 KKK24368.1 - 1e-31 109.5 0.1 8.6e-31 106.5 0.0 2.3 1 1 1 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.1 KKK24368.1 - 9.2e-18 63.6 5.3 1.5e-17 63.0 2.5 2.4 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.1 KKK24368.1 - 3.5e-05 23.5 2.3 6.5e-05 22.6 1.6 1.5 1 0 0 1 1 1 1 Ring finger domain Rtf2 PF04641.7 KKK24368.1 - 3.7e-05 23.0 0.1 3.7e-05 23.0 0.0 2.4 3 0 0 3 3 3 1 Rtf2 RING-finger zf-RING_5 PF14634.1 KKK24368.1 - 0.00075 19.1 2.2 0.0014 18.3 1.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KKK24368.1 - 0.0024 17.8 3.2 0.0046 16.9 2.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KKK24368.1 - 0.0083 15.7 2.6 0.014 15.0 1.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Corona_S2 PF01601.11 KKK24368.1 - 0.033 12.3 0.7 0.05 11.6 0.5 1.2 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein zf-C3HC4 PF00097.20 KKK24368.1 - 0.14 11.8 4.0 0.28 10.8 2.8 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KKK24368.1 - 0.27 11.1 3.2 0.59 10.0 2.2 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Syntaxin PF00804.20 KKK24368.1 - 2.4 8.3 8.4 0.092 12.9 1.0 2.2 2 2 0 2 2 2 0 Syntaxin PG_binding_1 PF01471.13 KKK24369.1 - 0.045 13.7 0.0 9.2 6.3 0.0 3.2 3 0 0 3 3 3 0 Putative peptidoglycan binding domain zf-HIT PF04438.11 KKK24371.1 - 2.7e-09 36.5 7.5 4.3e-09 35.8 5.2 1.4 1 0 0 1 1 1 1 HIT zinc finger zf-B_box PF00643.19 KKK24371.1 - 1.3 9.0 8.3 2.3 8.1 5.8 1.4 1 0 0 1 1 1 0 B-box zinc finger ERG2_Sigma1R PF04622.7 KKK24372.1 - 5e-70 235.1 0.1 1.4e-69 233.6 0.1 1.7 1 1 0 1 1 1 1 ERG2 and Sigma1 receptor like protein ATP_bind_3 PF01171.15 KKK24372.1 - 1.5e-18 66.9 0.0 2.8e-18 66.0 0.0 1.4 1 0 0 1 1 1 1 PP-loop family RecR PF02132.10 KKK24372.1 - 0.0015 17.9 1.2 0.0015 17.9 0.8 2.3 3 0 0 3 3 3 1 RecR protein DUF2392 PF10288.4 KKK24372.1 - 0.0092 16.3 0.0 0.022 15.1 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2392) RasGEF PF00617.14 KKK24373.1 - 3.5e-45 154.0 0.4 1e-44 152.5 0.1 1.8 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.15 KKK24373.1 - 1.8e-14 53.7 0.2 4.5e-14 52.4 0.1 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif Complex1_LYR_2 PF13233.1 KKK24373.1 - 4.5e-13 49.5 0.1 4.3e-12 46.4 0.0 2.6 3 0 0 3 3 3 1 Complex1_LYR-like Miro PF08477.8 KKK24373.1 - 3.4e-10 40.4 0.0 9.6e-10 38.9 0.0 1.8 2 0 0 2 2 2 1 Miro-like protein Ras PF00071.17 KKK24373.1 - 0.0039 16.5 0.0 0.0083 15.5 0.0 1.5 1 0 0 1 1 1 1 Ras family Cyclin_N PF00134.18 KKK24374.1 - 1.1e-11 44.3 0.0 1.9e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.6 KKK24374.1 - 2.7e-10 40.8 0.0 7.2e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Cyclin Glyco_hydro_12 PF01670.11 KKK24375.1 - 6.4e-36 123.4 2.1 9.1e-36 122.9 1.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 Acetyltransf_8 PF13523.1 KKK24376.1 - 1.6e-38 131.9 0.0 2.5e-38 131.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 KKK24376.1 - 0.0022 18.1 0.0 0.0046 17.1 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Bd3614-deam PF14439.1 KKK24376.1 - 0.2 11.4 0.0 0.34 10.7 0.0 1.3 1 0 0 1 1 1 0 Bd3614-like deaminase OCD_Mu_crystall PF02423.10 KKK24377.1 - 3.7e-12 45.6 0.0 2.5e-10 39.6 0.0 3.0 2 1 0 2 2 2 1 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.15 KKK24377.1 - 1.4e-06 28.4 0.0 4.2e-06 26.8 0.0 1.7 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase GFO_IDH_MocA PF01408.17 KKK24377.1 - 0.013 16.0 0.0 0.031 14.8 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Nucleic_acid_bd PF13820.1 KKK24377.1 - 0.098 12.2 0.0 0.27 10.8 0.0 1.8 1 0 0 1 1 1 0 Putative nucleic acid-binding region DASH_Dad2 PF08654.5 KKK24393.1 - 5.7e-37 125.8 2.6 7.7e-37 125.4 1.8 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad2 NPV_P10 PF05531.7 KKK24393.1 - 0.00048 20.3 3.2 0.3 11.3 0.5 2.1 2 0 0 2 2 2 2 Nucleopolyhedrovirus P10 protein Seryl_tRNA_N PF02403.17 KKK24393.1 - 0.0059 16.6 2.7 0.0059 16.6 0.6 1.8 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain Glutaredoxin2_C PF04399.8 KKK24393.1 - 0.1 12.1 0.7 0.15 11.6 0.5 1.2 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain Prefoldin_2 PF01920.15 KKK24393.1 - 0.12 12.1 2.0 2.8 7.7 0.1 2.3 1 1 1 2 2 2 0 Prefoldin subunit Phasin_2 PF09361.5 KKK24393.1 - 0.22 11.5 5.7 0.15 12.1 2.9 1.5 1 1 0 1 1 1 0 Phasin protein FTA4 PF13093.1 KKK24393.1 - 0.24 10.8 4.9 0.11 11.8 1.7 1.6 1 1 1 2 2 2 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 FUSC PF04632.7 KKK24393.1 - 0.85 7.9 4.0 0.9 7.8 2.8 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family bZIP_1 PF00170.16 KKK24393.1 - 1.7 8.6 7.7 0.62 10.0 2.6 2.3 2 1 0 2 2 2 0 bZIP transcription factor FlxA PF14282.1 KKK24393.1 - 3.2 7.7 12.9 1.8 8.5 1.6 2.4 1 1 1 2 2 2 0 FlxA-like protein Shugoshin_N PF07558.6 KKK24394.1 - 4.3e-16 58.3 3.7 4.3e-16 58.3 2.5 1.8 2 0 0 2 2 2 1 Shugoshin N-terminal coiled-coil region Shugoshin_C PF07557.6 KKK24394.1 - 3.1e-10 39.3 3.6 3.1e-10 39.3 2.5 3.0 2 0 0 2 2 2 1 Shugoshin C terminus p450 PF00067.17 KKK24395.1 - 1.6e-67 228.0 0.0 1.8e-67 227.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Ecl1 PF12855.2 KKK24396.1 - 1.1e-07 31.0 0.6 2.5e-07 29.8 0.4 1.7 1 1 0 1 1 1 1 Life-span regulatory factor PPI_Ypi1 PF07491.6 KKK24397.1 - 2.9e-25 87.6 5.8 2.1e-24 84.9 4.0 2.3 1 1 0 1 1 1 1 Protein phosphatase inhibitor TFIIF_alpha PF05793.7 KKK24397.1 - 0.015 13.6 10.4 0.016 13.6 7.2 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CDC45 PF02724.9 KKK24397.1 - 0.096 10.7 7.7 0.12 10.4 5.3 1.0 1 0 0 1 1 1 0 CDC45-like protein CAF-1_p150 PF11600.3 KKK24397.1 - 5.6 6.2 13.7 9.4 5.5 9.5 1.4 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal CRM1_C PF08767.6 KKK24398.1 - 1.2e-137 458.0 11.1 1.2e-137 458.0 7.7 2.9 3 1 0 3 3 3 1 CRM1 C terminal Xpo1 PF08389.7 KKK24398.1 - 1.2e-42 145.2 10.5 3.9e-42 143.6 4.5 3.4 2 1 1 3 3 3 1 Exportin 1-like protein IBN_N PF03810.14 KKK24398.1 - 3.7e-11 42.7 0.1 1.6e-10 40.7 0.1 2.3 1 0 0 1 1 1 1 Importin-beta N-terminal domain HD_assoc PF13286.1 KKK24398.1 - 0.099 12.9 2.5 8.2 6.7 0.1 3.9 4 0 0 4 4 4 0 Phosphohydrolase-associated domain DAO PF01266.19 KKK24399.1 - 1.5e-48 165.5 0.0 2.4e-48 164.8 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Aa_trans PF01490.13 KKK24399.1 - 4.3e-29 101.2 21.3 5.9e-29 100.7 14.8 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein FAD_binding_2 PF00890.19 KKK24399.1 - 1.4e-09 37.3 0.1 2.7e-09 36.3 0.1 1.4 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 KKK24399.1 - 1.7e-05 24.1 0.1 0.00026 20.2 0.1 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KKK24399.1 - 0.00054 19.8 0.2 0.0013 18.6 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KKK24399.1 - 0.0014 17.7 0.2 0.0037 16.4 0.0 1.6 2 0 0 2 2 2 1 Thi4 family 3HCDH_N PF02737.13 KKK24399.1 - 0.0015 18.1 0.2 0.0027 17.3 0.2 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_8 PF13450.1 KKK24399.1 - 0.003 17.5 0.2 0.0077 16.2 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 KKK24399.1 - 0.0073 14.8 0.5 0.011 14.2 0.3 1.2 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.17 KKK24399.1 - 0.0079 15.0 0.1 0.042 12.7 0.0 1.9 2 0 0 2 2 2 1 Glucose inhibited division protein A Trp_Tyr_perm PF03222.8 KKK24399.1 - 0.014 14.2 16.4 0.02 13.7 11.4 1.2 1 0 0 1 1 1 0 Tryptophan/tyrosine permease family GDI PF00996.13 KKK24399.1 - 0.02 13.2 0.0 0.032 12.5 0.0 1.3 1 0 0 1 1 1 0 GDP dissociation inhibitor Lycopene_cycl PF05834.7 KKK24399.1 - 0.021 13.7 0.0 0.054 12.4 0.0 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox PF00070.22 KKK24399.1 - 0.067 13.5 0.2 0.21 12.0 0.1 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_10 PF13460.1 KKK24399.1 - 0.078 12.9 0.2 0.31 11.0 0.1 2.1 1 0 0 1 1 1 0 NADH(P)-binding Sugar_tr PF00083.19 KKK24400.1 - 1.8e-86 290.5 26.8 2.2e-86 290.2 18.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KKK24400.1 - 9.8e-17 60.6 15.8 9.8e-17 60.6 11.0 2.2 1 1 0 2 2 2 1 Major Facilitator Superfamily Zn_clus PF00172.13 KKK24401.1 - 6.5e-10 38.7 8.2 1.3e-09 37.8 5.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KKK24401.1 - 1.3e-06 27.4 0.1 3.6e-06 26.0 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Sulfatase PF00884.18 KKK24402.1 - 1.2e-68 231.5 0.0 1.5e-68 231.2 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 KKK24402.1 - 1.3e-05 24.7 0.0 0.075 12.3 0.0 2.4 2 1 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase_C PF14707.1 KKK24402.1 - 0.00057 20.1 0.2 0.015 15.5 0.1 2.4 1 1 0 1 1 1 1 C-terminal region of aryl-sulfatase DUF229 PF02995.12 KKK24402.1 - 0.0026 16.2 0.0 0.0036 15.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Ribosomal_S26e PF01283.14 KKK24406.1 - 1.2e-10 41.5 0.1 1.3e-10 41.4 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e DUF2419 PF10343.4 KKK24406.1 - 0.04 13.1 0.0 0.04 13.1 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2419) Thioredoxin PF00085.15 KKK24412.1 - 3.6e-61 203.3 5.4 1.6e-31 108.0 0.1 4.4 5 0 0 5 5 5 2 Thioredoxin Thioredoxin_6 PF13848.1 KKK24412.1 - 8.2e-53 178.9 1.2 6.9e-40 136.8 0.1 3.6 3 1 1 4 4 4 3 Thioredoxin-like domain Thioredoxin_8 PF13905.1 KKK24412.1 - 3.6e-10 39.8 0.0 0.00094 19.2 0.0 3.3 4 0 0 4 4 4 2 Thioredoxin-like Calsequestrin PF01216.12 KKK24412.1 - 3.8e-10 39.0 1.6 1.5e-09 37.1 1.1 1.9 1 1 0 1 1 1 1 Calsequestrin Thioredoxin_2 PF13098.1 KKK24412.1 - 3.6e-09 36.8 3.1 0.0024 18.0 0.2 3.8 3 2 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_7 PF13899.1 KKK24412.1 - 1.4e-08 34.5 0.1 0.01 15.8 0.0 3.1 3 0 0 3 3 3 2 Thioredoxin-like AhpC-TSA PF00578.16 KKK24412.1 - 6.3e-07 29.1 2.5 0.0046 16.6 0.1 3.2 3 0 0 3 3 3 2 AhpC/TSA family Redoxin PF08534.5 KKK24412.1 - 8.6e-07 28.5 3.1 0.22 11.0 0.0 3.4 3 0 0 3 3 3 3 Redoxin Thioredoxin_4 PF13462.1 KKK24412.1 - 0.38 10.7 6.1 12 5.8 0.1 4.0 4 0 0 4 4 4 0 Thioredoxin UDG PF03167.14 KKK24413.1 - 3.3e-24 85.0 0.1 6e-24 84.2 0.1 1.4 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Med14 PF08638.6 KKK24414.1 - 4.5e-78 260.9 0.0 8.5e-78 260.0 0.0 1.5 1 0 0 1 1 1 1 Mediator complex subunit MED14 ATG22 PF11700.3 KKK24415.1 - 1.7e-214 712.7 20.4 1.9e-214 712.5 14.1 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.11 KKK24415.1 - 6.1e-11 41.6 41.0 1e-10 40.9 9.0 3.1 3 0 0 3 3 3 3 Major Facilitator Superfamily Mfp-3 PF04202.8 KKK24415.1 - 0.062 13.4 0.1 12 6.1 0.2 2.6 2 0 0 2 2 2 0 Foot protein 3 SHNi-TPR PF10516.4 KKK24416.1 - 1.7e-17 62.3 2.3 9.8e-17 59.9 0.1 2.8 2 0 0 2 2 2 1 SHNi-TPR TPR_11 PF13414.1 KKK24416.1 - 6.4e-08 32.1 2.7 0.0025 17.4 0.0 2.8 2 1 0 2 2 2 2 TPR repeat TPR_12 PF13424.1 KKK24416.1 - 2.3e-07 30.6 7.8 0.00071 19.4 0.1 3.1 4 0 0 4 4 3 2 Tetratricopeptide repeat CCDC-167 PF15188.1 KKK24416.1 - 0.00019 21.3 1.1 0.00069 19.5 0.7 1.9 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 167 TPR_1 PF00515.23 KKK24416.1 - 0.0014 18.0 2.4 0.38 10.4 0.8 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 KKK24416.1 - 0.079 13.6 6.9 10 6.9 2.7 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 KKK24416.1 - 0.13 12.1 11.9 2.2 8.3 1.1 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.1 KKK24416.1 - 0.14 12.8 2.1 53 4.8 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Creb_binding PF09030.5 KKK24416.1 - 0.25 11.5 5.1 0.053 13.7 0.7 2.1 2 0 0 2 2 2 0 Creb binding MIT PF04212.13 KKK24416.1 - 0.49 10.3 6.8 0.28 11.0 1.6 2.6 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain XhlA PF10779.4 KKK24416.1 - 9.7 6.1 7.9 12 5.9 0.9 3.1 2 1 0 2 2 2 0 Haemolysin XhlA DNA_pol_E_B PF04042.11 KKK24417.1 - 4.1e-50 169.9 0.0 5.5e-50 169.5 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DWNN PF08783.6 KKK24418.1 - 3.9e-33 113.2 0.9 5.7e-33 112.6 0.0 1.7 2 0 0 2 2 2 1 DWNN domain zf-CCHC_2 PF13696.1 KKK24418.1 - 6.7e-06 25.5 7.3 1.9e-05 24.0 5.1 1.8 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 KKK24418.1 - 0.019 14.8 1.2 0.019 14.8 0.8 2.8 3 0 0 3 3 3 0 Zinc knuckle zf-Nse PF11789.3 KKK24418.1 - 0.26 10.8 3.9 0.52 9.8 2.7 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4 PF00097.20 KKK24418.1 - 1.9 8.2 8.7 4.2 7.1 6.0 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KKK24418.1 - 2.3 7.9 11.0 0.13 12.0 3.4 2.1 2 0 0 2 2 2 0 zinc-RING finger domain zf-C3HC4_4 PF15227.1 KKK24418.1 - 8 6.4 10.0 21 5.1 6.9 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Yippee-Mis18 PF03226.9 KKK24419.1 - 4.2e-23 81.1 0.1 6.4e-23 80.6 0.1 1.3 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RIG-I_C-RD PF11648.3 KKK24419.1 - 0.013 15.3 0.3 0.3 10.9 0.0 2.1 2 0 0 2 2 2 0 C-terminal domain of RIG-I Transp_Tc5_C PF04236.10 KKK24419.1 - 0.054 13.7 0.6 1 9.6 0.1 2.3 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain zf-ribbon_3 PF13248.1 KKK24419.1 - 0.11 11.7 1.9 0.97 8.7 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain dCMP_cyt_deam_1 PF00383.17 KKK24420.1 - 7.4e-27 92.9 1.5 1.1e-26 92.3 1.1 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region AAA_18 PF13238.1 KKK24420.1 - 0.0048 17.2 0.0 0.0098 16.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KKK24420.1 - 0.0068 17.2 0.1 0.015 16.0 0.1 1.8 1 1 0 1 1 1 1 AAA domain CoaE PF01121.15 KKK24420.1 - 0.023 14.1 0.0 0.044 13.1 0.0 1.4 1 0 0 1 1 1 0 Dephospho-CoA kinase His_biosynth PF00977.16 KKK24421.1 - 1e-48 165.5 0.7 4.8e-48 163.4 0.5 2.1 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.23 KKK24421.1 - 3.8e-29 101.5 0.0 6.5e-29 100.7 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I SNO PF01174.14 KKK24421.1 - 7.9e-12 45.1 0.0 3.9e-09 36.4 0.0 2.2 2 0 0 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.9 KKK24421.1 - 3.6e-08 33.1 0.0 2.3e-07 30.5 0.0 2.2 3 0 0 3 3 3 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_C26 PF07722.8 KKK24421.1 - 0.0014 18.1 0.0 0.003 17.0 0.0 1.6 1 0 0 1 1 1 1 Peptidase C26 Dus PF01207.12 KKK24421.1 - 0.0022 16.9 0.0 0.0046 15.8 0.0 1.5 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) ThiG PF05690.9 KKK24421.1 - 0.086 11.8 0.9 0.12 11.4 0.1 1.5 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG Fungal_trans PF04082.13 KKK24423.1 - 1.1e-12 47.3 0.0 2.3e-12 46.3 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain TRP PF06011.7 KKK24424.1 - 1.9e-137 458.4 6.8 2.4e-137 458.1 4.7 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 KKK24424.1 - 1.2e-40 138.8 0.4 1.8e-40 138.2 0.3 1.3 1 0 0 1 1 1 1 ML-like domain Hep_59 PF07052.6 KKK24425.1 - 1.6e-22 79.8 4.4 1.6e-21 76.5 0.0 2.8 3 0 0 3 3 3 1 Hepatocellular carcinoma-associated antigen 59 Chorion_2 PF03964.10 KKK24425.1 - 0.025 15.1 0.6 0.025 15.1 0.4 2.5 2 1 1 3 3 3 0 Chorion family 2 Actin PF00022.14 KKK24426.1 - 7.1e-144 479.0 0.0 8e-144 478.8 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 KKK24426.1 - 0.0027 16.3 0.0 5.6 5.4 0.0 3.0 3 0 0 3 3 3 3 MreB/Mbl protein DEAD PF00270.24 KKK24427.1 - 1.5e-47 161.2 0.1 1.2e-46 158.3 0.0 2.2 2 1 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KKK24427.1 - 1e-28 99.0 0.1 5.9e-27 93.3 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KKK24427.1 - 8.6e-06 25.7 0.0 1.8e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 KKK24427.1 - 0.00051 19.1 0.1 0.00051 19.1 0.1 2.3 3 1 1 4 4 4 1 U3-containing 90S pre-ribosomal complex subunit DUF1253 PF06862.7 KKK24427.1 - 0.011 14.1 0.0 0.62 8.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1253) Rep_fac-A_C PF08646.5 KKK24428.1 - 6.2e-57 191.3 1.7 1.5e-54 183.7 0.5 2.3 2 0 0 2 2 2 2 Replication factor-A C terminal domain Rep-A_N PF04057.7 KKK24428.1 - 5e-22 77.5 0.0 1.3e-21 76.2 0.0 1.8 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.20 KKK24428.1 - 4.2e-14 52.1 0.5 5.4e-10 39.0 0.0 3.7 4 0 0 4 4 4 2 OB-fold nucleic acid binding domain DUF223 PF02721.9 KKK24428.1 - 0.048 13.7 0.0 0.13 12.3 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function DUF223 OST3_OST6 PF04756.8 KKK24429.1 - 6.6e-20 71.2 2.5 8.5e-20 70.9 1.7 1.1 1 0 0 1 1 1 1 OST3 / OST6 family VIT1 PF01988.14 KKK24429.1 - 0.024 14.1 11.0 0.18 11.2 1.1 2.1 1 1 1 2 2 2 0 VIT family Rft-1 PF04506.8 KKK24430.1 - 2.7e-28 98.6 3.9 3.4e-28 98.3 2.7 1.1 1 0 0 1 1 1 1 Rft protein Polysacc_synt_C PF14667.1 KKK24430.1 - 0.008 15.9 8.3 0.012 15.4 5.8 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis C-terminal domain CbiM PF01891.11 KKK24430.1 - 0.012 15.2 3.1 0.02 14.5 2.2 1.4 1 0 0 1 1 1 0 Cobalt uptake substrate-specific transmembrane region DUF1290 PF06947.7 KKK24430.1 - 0.02 14.8 0.6 0.037 13.9 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1290) YqhR PF11085.3 KKK24430.1 - 0.63 9.5 7.2 0.26 10.8 0.8 2.3 1 1 0 2 2 2 0 Conserved membrane protein YqhR Fun_ATP-synt_8 PF05933.8 KKK24430.1 - 1.2 9.2 5.7 0.47 10.5 1.3 2.3 2 0 0 2 2 2 0 Fungal ATP synthase protein 8 (A6L) GAS PF13851.1 KKK24431.1 - 0.0047 16.1 12.6 0.0047 16.1 8.7 2.8 1 1 2 3 3 3 1 Growth-arrest specific micro-tubule binding Utp11 PF03998.8 KKK24431.1 - 0.099 12.4 13.3 0.17 11.6 8.6 1.7 1 1 0 1 1 1 0 Utp11 protein AAA_13 PF13166.1 KKK24431.1 - 5.2 5.4 17.9 2.4 6.5 10.8 1.5 2 0 0 2 2 2 0 AAA domain ThiF PF00899.16 KKK24433.1 - 2e-28 98.9 0.0 3.3e-28 98.1 0.0 1.4 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.15 KKK24433.1 - 0.00082 19.4 0.0 0.0023 18.0 0.0 1.7 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase ApbA PF02558.11 KKK24433.1 - 0.075 12.4 0.0 0.15 11.4 0.0 1.6 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.14 KKK24433.1 - 0.11 11.5 0.0 0.57 9.3 0.0 2.0 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FtsJ PF01728.14 KKK24434.1 - 3.2e-60 203.2 0.0 3.8e-60 202.9 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_23 PF13489.1 KKK24434.1 - 0.0043 16.7 0.0 0.0066 16.1 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KKK24434.1 - 0.0097 16.4 0.0 0.024 15.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain UCH PF00443.24 KKK24435.1 - 7.6e-46 156.3 0.0 1.5e-45 155.3 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 KKK24435.1 - 1.2e-24 86.1 19.7 2.1e-20 72.5 1.2 3.8 3 2 1 4 4 4 2 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.1 KKK24435.1 - 9.9e-18 64.5 0.0 1.5e-16 60.7 0.0 2.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UBA PF00627.26 KKK24435.1 - 1.4e-17 62.9 0.3 3.8e-09 36.1 0.1 2.7 2 0 0 2 2 2 2 UBA/TS-N domain UBA_4 PF14555.1 KKK24435.1 - 0.017 14.6 0.0 0.036 13.5 0.0 1.6 1 0 0 1 1 1 0 UBA-like domain TerY-C PF15616.1 KKK24435.1 - 1.7 8.5 8.9 1.9 8.4 0.3 3.3 4 0 0 4 4 4 0 TerY-C metal binding domain FAD_binding_3 PF01494.14 KKK24442.1 - 1.1e-16 60.8 0.1 4.2e-12 45.7 0.1 2.3 2 0 0 2 2 2 2 FAD binding domain SE PF08491.5 KKK24442.1 - 0.0027 16.5 0.0 0.03 13.1 0.0 2.0 2 0 0 2 2 2 1 Squalene epoxidase Lycopene_cycl PF05834.7 KKK24442.1 - 0.0077 15.1 0.2 0.17 10.7 0.0 2.5 2 1 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 KKK24442.1 - 0.092 12.7 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 KKK24442.1 - 0.13 10.6 0.0 0.2 10.1 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein adh_short PF00106.20 KKK24443.1 - 3.9e-19 69.1 0.0 1.2e-18 67.5 0.0 1.7 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KKK24443.1 - 1.3e-07 31.4 0.0 0.00065 19.4 0.0 2.2 2 0 0 2 2 2 2 KR domain adh_short_C2 PF13561.1 KKK24443.1 - 3.1e-06 27.1 0.0 0.0007 19.4 0.0 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase Peptidase_S29 PF02907.10 KKK24443.1 - 0.11 12.0 0.3 0.18 11.3 0.2 1.3 1 0 0 1 1 1 0 Hepatitis C virus NS3 protease Zn_clus PF00172.13 KKK24444.1 - 2e-06 27.5 8.7 2.9e-06 27.0 6.0 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ADH_zinc_N PF00107.21 KKK24445.1 - 4.4e-11 42.4 0.0 8.4e-11 41.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KKK24445.1 - 3.5e-06 26.7 1.3 3.8e-05 23.3 0.1 2.6 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 KKK24445.1 - 0.00084 20.2 0.0 0.0025 18.7 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase AMP-binding PF00501.23 KKK24446.1 - 1.4e-82 277.3 0.5 3.3e-82 276.1 0.1 1.7 2 0 0 2 2 2 1 AMP-binding enzyme ketoacyl-synt PF00109.21 KKK24446.1 - 6.8e-74 248.5 0.0 1.3e-73 247.6 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 KKK24446.1 - 5.8e-50 170.4 0.1 1.2e-49 169.3 0.1 1.5 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 KKK24446.1 - 1.5e-49 168.1 0.4 1.7e-48 164.6 0.1 2.9 3 0 0 3 3 2 1 KR domain PS-DH PF14765.1 KKK24446.1 - 9.9e-44 149.6 0.2 1.6e-43 148.9 0.1 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Condensation PF00668.15 KKK24446.1 - 6e-41 140.2 0.0 1.2e-40 139.2 0.0 1.5 1 0 0 1 1 1 1 Condensation domain adh_short PF00106.20 KKK24446.1 - 1.3e-40 138.9 0.1 6.2e-39 133.5 0.0 3.2 3 0 0 3 3 2 1 short chain dehydrogenase NAD_binding_4 PF07993.7 KKK24446.1 - 1.8e-32 112.2 0.1 6.1e-32 110.5 0.0 1.9 3 0 0 3 3 2 1 Male sterility protein Ketoacyl-synt_C PF02801.17 KKK24446.1 - 3.2e-30 104.4 0.0 7.9e-30 103.1 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 KKK24446.1 - 4.7e-21 75.1 0.1 1.8e-20 73.2 0.0 2.1 2 0 0 2 2 1 1 Methyltransferase domain PP-binding PF00550.20 KKK24446.1 - 1.5e-15 57.1 0.3 3.8e-06 27.0 0.2 3.4 3 0 0 3 3 3 2 Phosphopantetheine attachment site Methyltransf_11 PF08241.7 KKK24446.1 - 7.4e-14 52.0 0.0 3.5e-13 49.8 0.0 2.3 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KKK24446.1 - 2.4e-12 46.8 0.0 6.6e-12 45.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KKK24446.1 - 3.7e-11 42.8 0.0 1.2e-10 41.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain HxxPF_rpt PF13745.1 KKK24446.1 - 5.8e-11 42.5 0.1 3.3e-10 40.1 0.0 2.5 2 0 0 2 2 1 1 HxxPF-repeated domain Methyltransf_18 PF12847.2 KKK24446.1 - 1e-09 38.9 0.0 6e-09 36.4 0.0 2.4 2 0 0 2 2 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KKK24446.1 - 5.9e-09 35.3 0.0 1.4e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 KKK24446.1 - 2.3e-07 31.1 0.0 8e-07 29.3 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.18 KKK24446.1 - 2.6e-07 29.9 0.2 1.9e-06 27.0 0.1 2.1 2 0 0 2 2 2 1 Thiolase, N-terminal domain Epimerase PF01370.16 KKK24446.1 - 5.8e-07 29.1 0.0 1.8e-06 27.5 0.0 1.8 2 0 0 2 2 1 1 NAD dependent epimerase/dehydratase family NodS PF05401.6 KKK24446.1 - 2.4e-05 23.8 0.0 4.9e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Nodulation protein S (NodS) RrnaAD PF00398.15 KKK24446.1 - 0.0011 17.9 0.0 0.012 14.7 0.0 2.1 2 0 0 2 2 2 1 Ribosomal RNA adenine dimethylase Methyltransf_16 PF10294.4 KKK24446.1 - 0.013 14.9 0.0 0.035 13.5 0.0 1.7 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_28 PF02636.12 KKK24446.1 - 0.16 11.3 0.0 0.3 10.4 0.0 1.4 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase NUMOD1 PF07453.8 KKK24446.1 - 0.32 10.8 0.0 0.84 9.5 0.0 1.6 1 0 0 1 1 1 0 NUMOD1 domain RTA1 PF04479.8 KKK24447.1 - 2.7e-33 115.3 5.1 5.5e-33 114.3 3.6 1.4 1 1 0 1 1 1 1 RTA1 like protein DUF3382 PF11862.3 KKK24447.1 - 0.054 13.4 1.5 0.16 11.8 1.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3382) MFS_1 PF07690.11 KKK24448.1 - 2.5e-39 135.0 50.5 1e-38 133.0 32.0 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KKK24448.1 - 5.6e-12 44.6 18.5 7.6e-12 44.2 12.8 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 KKK24448.1 - 2.7e-07 29.5 14.8 2.7e-07 29.5 10.2 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter TPR_11 PF13414.1 KKK24464.1 - 5.1e-49 163.8 25.9 6.6e-12 44.9 0.6 7.8 3 2 5 9 9 9 8 TPR repeat TPR_1 PF00515.23 KKK24464.1 - 1.2e-40 135.4 26.0 5.2e-07 29.0 0.0 11.5 10 1 1 11 11 11 9 Tetratricopeptide repeat TPR_2 PF07719.12 KKK24464.1 - 1.1e-38 128.0 26.3 4.9e-06 26.0 0.1 10.7 10 0 0 10 10 10 8 Tetratricopeptide repeat TPR_16 PF13432.1 KKK24464.1 - 1.9e-25 88.8 19.5 4.1e-07 30.4 0.3 6.8 6 1 1 7 7 6 4 Tetratricopeptide repeat TPR_12 PF13424.1 KKK24464.1 - 4.7e-24 84.1 25.3 1.4e-07 31.3 0.0 7.5 3 1 3 7 7 7 4 Tetratricopeptide repeat TPR_8 PF13181.1 KKK24464.1 - 5.6e-19 66.4 20.7 0.0034 17.0 0.1 10.0 9 1 1 10 10 10 5 Tetratricopeptide repeat TPR_14 PF13428.1 KKK24464.1 - 4.1e-15 54.9 15.8 0.04 14.5 0.1 9.6 4 2 6 10 10 9 6 Tetratricopeptide repeat TPR_17 PF13431.1 KKK24464.1 - 5.1e-15 54.3 15.5 0.038 14.1 0.0 9.1 10 0 0 10 10 8 3 Tetratricopeptide repeat TPR_9 PF13371.1 KKK24464.1 - 6.3e-15 54.7 8.9 1.3e-06 28.1 0.2 6.4 3 2 4 7 7 7 4 Tetratricopeptide repeat TPR_7 PF13176.1 KKK24464.1 - 5.6e-13 47.6 14.1 0.026 14.3 0.1 8.5 7 2 1 8 8 8 3 Tetratricopeptide repeat TPR_19 PF14559.1 KKK24464.1 - 4.3e-12 46.1 16.9 2.1e-05 24.7 0.3 6.3 4 1 4 8 8 8 4 Tetratricopeptide repeat Apc3 PF12895.2 KKK24464.1 - 3.6e-10 39.8 16.7 0.0047 17.0 0.2 5.5 3 1 2 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 SHNi-TPR PF10516.4 KKK24464.1 - 5.1e-05 22.4 10.4 0.56 9.4 0.0 6.2 6 0 0 6 6 6 2 SHNi-TPR TPR_6 PF13174.1 KKK24464.1 - 0.00044 20.5 23.7 3.3 8.3 0.5 8.5 9 0 0 9 9 8 1 Tetratricopeptide repeat MAS20 PF02064.10 KKK24464.1 - 0.0028 17.5 8.0 3.7 7.4 1.7 4.3 3 2 1 4 4 4 1 MAS20 protein import receptor BLVR PF06375.6 KKK24464.1 - 0.0034 17.2 6.1 0.0073 16.1 4.2 1.5 1 0 0 1 1 1 1 Bovine leukaemia virus receptor (BLVR) DUF1510 PF07423.6 KKK24464.1 - 0.0063 15.9 5.3 0.011 15.1 3.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) ARL6IP6 PF15062.1 KKK24464.1 - 0.011 15.6 0.1 0.028 14.3 0.0 1.7 1 0 0 1 1 1 0 Haemopoietic lineage transmembrane helix TPR_10 PF13374.1 KKK24464.1 - 0.012 15.5 7.3 2.5 8.1 0.3 5.3 6 0 0 6 6 4 0 Tetratricopeptide repeat Sel1 PF08238.7 KKK24464.1 - 0.063 13.9 6.5 0.86 10.3 0.1 4.0 4 0 0 4 4 2 0 Sel1 repeat Apc5 PF12862.2 KKK24464.1 - 0.17 11.7 8.3 14 5.5 0.2 4.5 2 2 1 3 3 3 0 Anaphase-promoting complex subunit 5 IFT43 PF15305.1 KKK24464.1 - 0.26 11.3 6.6 0.51 10.3 4.6 1.4 1 0 0 1 1 1 0 Intraflagellar transport protein 43 NARP1 PF12569.3 KKK24464.1 - 0.32 9.6 24.2 0.35 9.5 0.4 4.6 2 1 2 4 4 4 0 NMDA receptor-regulated protein 1 FHA PF00498.21 KKK24465.1 - 3.1e-13 49.6 0.1 1.1e-12 47.8 0.0 2.0 2 0 0 2 2 2 1 FHA domain Aminotran_4 PF01063.14 KKK24466.1 - 3.4e-39 134.6 0.0 4.3e-39 134.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class IV PRELI PF04707.9 KKK24467.1 - 4.4e-22 78.3 0.0 3.8e-20 72.0 0.0 2.2 2 0 0 2 2 2 2 PRELI-like family An_peroxidase PF03098.10 KKK24468.1 - 2.6e-89 300.0 0.0 3.6e-70 236.8 0.0 2.2 1 1 1 2 2 2 2 Animal haem peroxidase p450 PF00067.17 KKK24468.1 - 4.5e-06 25.4 0.0 0.00076 18.1 0.0 2.2 2 0 0 2 2 2 2 Cytochrome P450 HUN PF08729.5 KKK24484.1 - 5.4e-14 51.7 0.3 5.4e-14 51.7 0.2 2.0 2 0 0 2 2 2 1 HPC2 and ubinuclein domain Glyco_hydro_18 PF00704.23 KKK24485.1 - 5.5e-37 127.9 0.0 6.7e-37 127.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.14 KKK24485.1 - 5.5e-08 32.6 8.4 5.5e-08 32.6 5.8 3.0 2 1 0 2 2 2 2 Chitin recognition protein Glyco_transf_8 PF01501.15 KKK24487.1 - 5.2e-14 52.1 0.0 5.5e-14 52.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl transferase family 8 RPAP1_C PF08620.5 KKK24488.1 - 7.8e-29 99.3 0.0 1.4e-28 98.5 0.0 1.4 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.5 KKK24488.1 - 7.5e-17 60.6 6.8 1.6e-16 59.6 4.7 1.6 1 0 0 1 1 1 1 RPAP1-like, N-terminal Apc1 PF12859.2 KKK24489.1 - 1e-32 112.4 0.7 4.3e-32 110.4 0.1 2.4 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 1 PC_rep PF01851.17 KKK24489.1 - 0.00085 19.4 8.1 0.46 10.8 0.0 4.7 5 0 0 5 5 5 3 Proteasome/cyclosome repeat MIT PF04212.13 KKK24496.1 - 0.00027 20.7 0.2 0.00052 19.8 0.1 1.4 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain TPR_1 PF00515.23 KKK24496.1 - 0.12 12.0 0.1 0.22 11.1 0.1 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat Exo_endo_phos PF03372.18 KKK24497.1 - 3.1e-14 53.5 0.2 6.2e-14 52.5 0.2 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 KKK24497.1 - 0.17 11.5 1.9 1.4 8.5 0.1 3.0 2 1 0 2 2 2 0 Endonuclease-reverse transcriptase AAA PF00004.24 KKK24498.1 - 3.8e-14 52.9 0.0 0.00046 20.4 0.0 3.4 3 0 0 3 3 3 3 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KKK24498.1 - 1.2e-09 38.3 0.2 0.041 14.0 0.0 4.7 3 1 0 3 3 3 2 AAA domain AAA_17 PF13207.1 KKK24498.1 - 7.3e-09 36.4 0.1 0.073 13.9 0.0 4.0 3 1 0 3 3 3 2 AAA domain AAA_18 PF13238.1 KKK24498.1 - 2.2e-06 28.0 0.0 0.43 10.8 0.0 3.7 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.1 KKK24498.1 - 4e-05 23.6 0.0 0.82 9.6 0.0 3.6 3 0 0 3 3 3 2 AAA ATPase domain AAA_19 PF13245.1 KKK24498.1 - 4e-05 23.2 3.4 0.0069 16.1 0.0 3.9 3 1 0 3 3 3 1 Part of AAA domain Torsin PF06309.6 KKK24498.1 - 7.8e-05 22.5 0.0 0.047 13.5 0.0 2.7 2 0 0 2 2 2 1 Torsin AAA_33 PF13671.1 KKK24498.1 - 8.4e-05 22.4 0.1 0.049 13.5 0.0 3.8 3 1 0 3 3 3 1 AAA domain AAA_5 PF07728.9 KKK24498.1 - 0.0022 17.7 0.2 1.2 8.8 0.0 3.1 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 KKK24498.1 - 0.0024 17.0 0.0 0.27 10.3 0.0 2.8 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.1 KKK24498.1 - 0.0057 16.6 2.7 4.6 7.1 0.0 3.7 4 0 0 4 4 4 2 AAA domain Sigma54_activ_2 PF14532.1 KKK24498.1 - 0.0089 16.0 0.0 0.11 12.5 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain RuvB_N PF05496.7 KKK24498.1 - 0.017 14.2 0.0 6.9 5.6 0.0 3.3 3 0 0 3 3 3 0 Holliday junction DNA helicase ruvB N-terminus AAA_30 PF13604.1 KKK24498.1 - 0.079 12.5 0.1 3.5 7.1 0.0 2.8 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.17 KKK24498.1 - 0.15 12.2 0.1 6.9 6.9 0.0 3.5 5 1 0 5 5 5 0 RNA helicase Ald_Xan_dh_C2 PF02738.13 KKK24499.1 - 8e-186 618.5 0.2 1.1e-185 618.1 0.2 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.16 KKK24499.1 - 3.1e-41 140.6 0.0 5.3e-41 139.9 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase CO_deh_flav_C PF03450.12 KKK24499.1 - 1e-31 108.9 0.1 6.8e-31 106.2 0.0 2.4 2 0 0 2 2 2 1 CO dehydrogenase flavoprotein C-terminal domain Ald_Xan_dh_C PF01315.17 KKK24499.1 - 7.4e-28 96.8 0.0 1.8e-27 95.6 0.0 1.7 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2_2 PF01799.15 KKK24499.1 - 3.8e-25 87.5 0.0 1e-24 86.2 0.0 1.8 1 0 0 1 1 1 1 [2Fe-2S] binding domain Fer2 PF00111.22 KKK24499.1 - 4.8e-08 32.6 0.1 2.7e-07 30.2 0.0 2.4 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain tRNA-synt_1c PF00749.16 KKK24501.1 - 4.4e-93 311.3 0.0 6.4e-93 310.8 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 KKK24501.1 - 2.6e-31 108.6 0.0 7.5e-31 107.1 0.0 1.8 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain Btz PF09405.5 KKK24502.1 - 5.8e-34 116.9 3.3 5.8e-34 116.9 2.3 2.1 3 0 0 3 3 3 1 CASC3/Barentsz eIF4AIII binding Ino80_Iec3 PF14612.1 KKK24503.1 - 3.5e-87 292.3 0.0 5e-87 291.8 0.0 1.2 1 0 0 1 1 1 1 IEC3 subunit of the Ino80 complex, chromatin re-modelling RRM_6 PF14259.1 KKK24504.1 - 3.4e-24 84.6 0.1 6.3e-12 45.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KKK24504.1 - 9.9e-22 76.3 0.4 8.8e-13 47.6 0.1 3.1 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KKK24504.1 - 4.5e-10 39.2 0.1 5.3e-05 22.9 0.1 2.7 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KKK24504.1 - 0.0049 16.6 0.1 0.016 14.9 0.0 1.8 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif Rsc14 PF08586.5 KKK24504.1 - 0.14 12.6 0.2 0.33 11.4 0.1 1.5 1 0 0 1 1 1 0 RSC complex, Rsc14/Ldb7 subunit IFRD PF05004.8 KKK24505.1 - 3.9e-28 98.4 2.2 5.1e-28 98.0 1.5 1.1 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) Cnd3 PF12719.2 KKK24505.1 - 2e-05 23.7 0.1 3.6e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Nuclear condensing complex subunits, C-term domain Corona_nucleoca PF00937.13 KKK24505.1 - 0.043 12.7 7.2 0.091 11.6 5.0 1.5 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein HEAT PF02985.17 KKK24505.1 - 0.05 13.7 0.0 20 5.5 0.0 2.9 2 0 0 2 2 2 0 HEAT repeat ECR1_N PF14382.1 KKK24506.1 - 6.9e-10 38.0 0.0 1.7e-09 36.8 0.0 1.7 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region EXOSC1 PF10447.4 KKK24506.1 - 0.0016 18.3 0.1 0.028 14.3 0.1 2.4 1 1 0 1 1 1 1 Exosome component EXOSC1/CSL4 SH2_2 PF14633.1 KKK24507.1 - 8.7e-81 270.1 0.0 2.9e-80 268.5 0.0 1.9 1 0 0 1 1 1 1 SH2 domain DLD PF14878.1 KKK24507.1 - 1.7e-37 127.9 4.9 1.7e-37 127.9 3.4 2.8 2 0 0 2 2 2 1 Death-like domain of SPT6 YqgF PF14639.1 KKK24507.1 - 7.2e-31 106.7 0.1 3.2e-30 104.6 0.0 2.2 2 0 0 2 2 2 1 Holliday-junction resolvase-like of SPT6 HHH_7 PF14635.1 KKK24507.1 - 8.1e-31 106.2 0.1 1.6e-30 105.2 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif SPT6_acidic PF14632.1 KKK24507.1 - 1.8e-21 76.1 29.4 1.8e-21 76.1 20.4 5.0 4 2 1 5 5 5 1 Acidic N-terminal SPT6 HTH_44 PF14641.1 KKK24507.1 - 1e-17 64.2 9.9 1.5e-17 63.7 3.5 3.3 2 1 0 2 2 2 1 Helix-turn-helix DNA-binding domain of SPT6 SH2 PF00017.19 KKK24507.1 - 2.4e-05 24.0 0.0 6.1e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 SH2 domain HHH_3 PF12836.2 KKK24507.1 - 0.014 15.3 0.0 0.033 14.1 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif DUF2716 PF10898.3 KKK24507.1 - 0.032 14.2 0.2 0.22 11.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2716) B12-binding PF02310.14 KKK24507.1 - 0.05 13.4 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 B12 binding domain Oxysterol_BP PF01237.13 KKK24508.1 - 1e-114 382.7 0.0 1.9e-114 381.8 0.0 1.4 1 0 0 1 1 1 1 Oxysterol-binding protein PH_8 PF15409.1 KKK24508.1 - 1e-37 128.0 0.5 1.8e-37 127.2 0.0 1.7 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.24 KKK24508.1 - 6.3e-06 26.3 0.0 1.4e-05 25.2 0.0 1.7 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 KKK24508.1 - 0.00049 20.3 0.6 0.013 15.7 0.4 2.6 1 1 0 1 1 1 1 Pleckstrin homology domain NAD_binding_10 PF13460.1 KKK24509.1 - 2.8e-06 27.4 0.0 3.9e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 KKK24509.1 - 0.0085 15.0 0.0 0.012 14.5 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Semialdhyde_dh PF01118.19 KKK24509.1 - 0.039 14.2 0.0 0.062 13.6 0.0 1.3 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain CbiN PF02553.10 KKK24509.1 - 0.063 13.2 0.1 0.13 12.2 0.1 1.5 1 0 0 1 1 1 0 Cobalt transport protein component CbiN Epimerase PF01370.16 KKK24509.1 - 0.065 12.6 0.0 0.08 12.3 0.0 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Mac PF12464.3 KKK24510.1 - 9.1e-21 73.6 0.2 2.5e-20 72.2 0.2 1.9 1 0 0 1 1 1 1 Maltose acetyltransferase Hexapep PF00132.19 KKK24510.1 - 1.1e-11 43.6 12.0 5e-11 41.5 3.1 3.1 3 0 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 KKK24510.1 - 2.3e-11 43.0 9.1 2.1e-10 39.9 3.6 2.7 2 1 0 2 2 2 1 Hexapeptide repeat of succinyl-transferase Zn_clus PF00172.13 KKK24510.1 - 1.3e-07 31.3 7.5 1.3e-07 31.3 5.2 2.1 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1488 PF07369.6 KKK24510.1 - 0.086 12.6 0.0 0.23 11.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1488) Glyco_transf_54 PF04666.8 KKK24512.1 - 2e-13 49.7 0.1 8.5e-11 41.1 0.1 3.0 2 1 0 2 2 2 2 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region Abhydrolase_6 PF12697.2 KKK24513.1 - 2.1e-14 53.9 0.6 4.3e-14 52.9 0.4 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KKK24513.1 - 2.3e-10 40.3 0.0 4.3e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 KKK24513.1 - 0.00062 19.3 0.0 0.001 18.6 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) DUF676 PF05057.9 KKK24513.1 - 0.0034 16.7 0.0 0.0051 16.1 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) DUF1749 PF08538.5 KKK24513.1 - 0.0082 15.0 0.0 0.021 13.7 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1749) Abhydrolase_2 PF02230.11 KKK24513.1 - 0.023 14.1 0.0 4.8 6.5 0.0 2.1 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.15 KKK24513.1 - 0.038 13.5 0.1 0.067 12.7 0.0 1.5 1 1 0 1 1 1 0 alpha/beta hydrolase fold DUF2305 PF10230.4 KKK24513.1 - 0.052 12.9 0.0 0.094 12.1 0.0 1.5 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2305) NAD_binding_4 PF07993.7 KKK24514.1 - 0.00056 18.9 0.0 0.027 13.4 0.0 2.3 2 0 0 2 2 2 1 Male sterility protein Semialdhyde_dh PF01118.19 KKK24514.1 - 0.0058 16.9 0.0 0.013 15.7 0.0 1.6 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 KKK24514.1 - 0.015 15.2 0.0 0.032 14.1 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Polysacc_synt_2 PF02719.10 KKK24514.1 - 0.023 13.5 0.1 0.11 11.3 0.0 1.9 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Epimerase PF01370.16 KKK24514.1 - 0.082 12.3 0.1 0.82 9.0 0.0 2.3 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KKK24514.1 - 0.11 11.2 0.0 0.58 8.8 0.0 2.1 2 1 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family p450 PF00067.17 KKK24515.1 - 4.5e-52 177.0 0.0 6e-52 176.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FSH1 PF03959.8 KKK24516.1 - 3.3e-25 88.7 0.0 3.8e-25 88.5 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.11 KKK24516.1 - 0.00042 19.8 0.0 0.0012 18.2 0.0 1.7 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 KKK24516.1 - 0.021 14.6 0.0 0.053 13.2 0.0 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family MazG PF03819.12 KKK24516.1 - 0.031 14.2 0.2 0.36 10.8 0.0 2.2 2 0 0 2 2 2 0 MazG nucleotide pyrophosphohydrolase domain TSC22 PF01166.13 KKK24516.1 - 0.085 12.8 0.1 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 TSC-22/dip/bun family Pkinase PF00069.20 KKK24517.1 - 3.4e-61 206.6 0.0 4.3e-61 206.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK24517.1 - 1.9e-36 125.4 0.0 2.6e-36 125.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KKK24517.1 - 1.3e-05 24.3 0.0 2.2e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 KKK24517.1 - 0.011 14.5 0.0 0.017 13.9 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.18 KKK24517.1 - 0.052 13.2 0.0 0.15 11.7 0.0 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.17 KKK24517.1 - 0.086 12.1 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 RIO1 family LysM PF01476.15 KKK24518.1 - 4.1e-28 96.9 0.2 1.5e-05 24.7 0.0 5.3 5 0 0 5 5 5 5 LysM domain Svf1 PF08622.5 KKK24546.1 - 7.4e-07 28.4 0.5 1.5e-06 27.4 0.5 1.4 2 0 0 2 2 2 1 Svf1-like Ribosomal_L11_N PF03946.9 KKK24547.1 - 5.8e-27 92.9 0.0 2.7e-26 90.7 0.1 1.8 2 0 0 2 2 2 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 KKK24547.1 - 2.2e-24 85.3 0.7 4.5e-24 84.3 0.1 1.7 2 0 0 2 2 2 1 Ribosomal protein L11, RNA binding domain Pkinase PF00069.20 KKK24548.1 - 9.2e-56 188.8 0.0 5.1e-55 186.4 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Mito_carr PF00153.22 KKK24548.1 - 1.1e-38 130.8 0.9 1.8e-14 53.1 0.1 3.6 3 0 0 3 3 3 3 Mitochondrial carrier protein Pkinase_Tyr PF07714.12 KKK24548.1 - 3.6e-19 68.8 0.0 5.9e-19 68.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KKK24548.1 - 0.028 14.1 0.2 0.067 12.9 0.1 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.1 KKK24548.1 - 0.22 10.4 0.0 0.53 9.2 0.0 1.6 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.9 KKK24548.1 - 0.45 9.5 0.9 0.75 8.8 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3337 PF11816.3 KKK24549.1 - 2.7e-100 336.0 5.1 4.9e-96 321.9 3.1 2.7 3 0 0 3 3 3 2 Domain of unknown function (DUF3337) ATP_bind_3 PF01171.15 KKK24549.1 - 1.2e-41 142.2 0.0 1.8e-40 138.3 0.0 2.3 1 1 0 1 1 1 1 PP-loop family WD40 PF00400.27 KKK24549.1 - 4.6e-23 80.2 21.0 1.9e-07 30.6 0.1 7.6 7 0 0 7 7 7 6 WD domain, G-beta repeat Asn_synthase PF00733.16 KKK24549.1 - 0.051 13.0 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Asparagine synthase ATP-synt_C PF00137.16 KKK24581.1 - 2.9e-14 52.6 10.8 4.2e-14 52.1 7.5 1.3 1 0 0 1 1 1 1 ATP synthase subunit C DUF4139 PF13598.1 KKK24582.1 - 1.6e-52 178.8 9.6 2e-38 132.5 0.1 3.2 3 1 0 3 3 3 2 Domain of unknown function (DUF4139) DUF4140 PF13600.1 KKK24582.1 - 5.6e-10 39.5 1.7 5.6e-10 39.5 1.2 5.0 3 2 1 4 4 4 1 N-terminal domain of unknown function (DUF4140) zf-CSL PF05207.8 KKK24583.1 - 2.1e-17 62.3 1.2 3.6e-17 61.5 0.9 1.4 1 0 0 1 1 1 1 CSL zinc finger DnaJ PF00226.26 KKK24583.1 - 2e-14 53.0 0.7 1.9e-13 49.8 0.5 2.1 1 1 0 1 1 1 1 DnaJ domain peroxidase PF00141.18 KKK24584.1 - 9.1e-51 172.5 0.0 1.5e-50 171.8 0.0 1.3 1 0 0 1 1 1 1 Peroxidase ArfGap PF01412.13 KKK24585.1 - 2.2e-37 127.3 0.3 3.5e-37 126.7 0.2 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf UBA PF00627.26 KKK24585.1 - 0.013 15.2 0.0 0.029 14.2 0.0 1.6 1 0 0 1 1 1 0 UBA/TS-N domain BTB PF00651.26 KKK24586.1 - 2.4e-13 50.0 0.1 4.5e-12 45.9 0.0 2.1 2 0 0 2 2 2 1 BTB/POZ domain DUF2987 PF11205.3 KKK24586.1 - 0.049 13.2 0.0 0.077 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2987) DUF4307 PF14155.1 KKK24586.1 - 0.11 12.3 0.0 0.23 11.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4307) JmjC PF02373.17 KKK24596.1 - 8.9e-37 125.8 0.8 8.9e-37 125.8 0.5 2.7 4 0 0 4 4 4 1 JmjC domain, hydroxylase zf-HC5HC2H PF13771.1 KKK24596.1 - 7e-18 64.5 4.4 1.6e-17 63.4 3.1 1.6 1 0 0 1 1 1 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 KKK24596.1 - 9.5e-18 64.2 5.0 1.9e-17 63.2 3.5 1.5 1 0 0 1 1 1 1 PHD-zinc-finger like domain JmjN PF02375.12 KKK24596.1 - 1.1e-15 56.7 0.3 2.9e-15 55.5 0.2 1.8 1 0 0 1 1 1 1 jmjN domain ACBP PF00887.14 KKK24597.1 - 1.7e-27 94.9 0.0 3e-27 94.1 0.0 1.4 1 0 0 1 1 1 1 Acyl CoA binding protein Atg14 PF10186.4 KKK24597.1 - 0.012 14.5 0.1 0.16 10.9 0.0 2.1 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 TraP PF07296.6 KKK24597.1 - 0.14 11.0 2.0 0.26 10.2 1.4 1.3 1 0 0 1 1 1 0 TraP protein Nop14 PF04147.7 KKK24597.1 - 5.9 4.6 23.0 10 3.9 15.9 1.2 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 KKK24597.1 - 7.9 4.3 14.3 12 3.8 9.9 1.2 1 0 0 1 1 1 0 CDC45-like protein Lin-8 PF03353.10 KKK24597.1 - 8.8 5.5 10.0 3 7.0 4.9 1.7 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist CHCH PF06747.8 KKK24598.1 - 1.8e-06 27.6 4.5 1.8e-06 27.6 3.1 2.5 3 0 0 3 3 3 2 CHCH domain Pet191_N PF10203.4 KKK24598.1 - 0.067 13.2 10.0 3.6 7.6 4.7 2.9 1 1 2 3 3 3 0 Cytochrome c oxidase assembly protein PET191 Cmc1 PF08583.5 KKK24598.1 - 0.53 10.0 14.7 1.2 8.9 3.0 2.3 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like COX6B PF02297.12 KKK24598.1 - 1 9.4 9.8 4.9 7.2 0.4 2.2 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb GTP_EFTU_D2 PF03144.20 KKK24609.1 - 1.1e-16 60.6 1.3 1.5e-16 60.2 0.9 1.2 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 KKK24609.1 - 2.5e-06 27.0 0.3 3.4e-06 26.6 0.2 1.2 1 0 0 1 1 1 1 Elongation factor Tu domain 4 GTP_EFTU_D3 PF03143.12 KKK24609.1 - 1.6e-05 24.9 0.1 0.0002 21.4 0.0 2.2 2 1 0 2 2 2 1 Elongation factor Tu C-terminal domain tRNA-synt_1g PF09334.6 KKK24619.1 - 2.3e-142 474.2 0.0 3e-142 473.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 KKK24619.1 - 4.3e-10 38.2 0.1 2.4e-06 25.8 0.0 3.8 2 2 1 3 3 3 2 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 KKK24619.1 - 0.03 14.0 0.0 0.065 12.9 0.0 1.5 1 0 0 1 1 1 0 Anticodon-binding domain of tRNA RNase_H2-Ydr279 PF09468.5 KKK24619.1 - 0.085 12.0 0.1 0.12 11.5 0.1 1.3 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) OppC_N PF12911.2 KKK24619.1 - 0.085 12.2 0.5 0.19 11.1 0.3 1.5 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C Elongin_A PF06881.6 KKK24619.1 - 0.13 12.6 2.0 0.34 11.3 1.4 1.7 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A DZR PF12773.2 KKK24619.1 - 0.89 9.4 5.1 3.2 7.6 3.5 1.9 1 1 0 1 1 1 0 Double zinc ribbon WD40 PF00400.27 KKK24620.1 - 1.1e-27 94.8 1.0 5.9e-06 25.9 0.0 5.3 5 0 0 5 5 5 4 WD domain, G-beta repeat BBS2_N PF14781.1 KKK24620.1 - 0.12 12.0 0.1 39 3.8 0.0 3.2 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, N-terminal PXA PF02194.10 KKK24622.1 - 2.9e-53 180.1 0.2 2.9e-53 180.1 0.1 2.6 3 0 0 3 3 3 1 PXA domain Nexin_C PF08628.7 KKK24622.1 - 1.7e-28 98.9 0.3 7.2e-28 96.9 0.0 2.3 2 0 0 2 2 2 1 Sorting nexin C terminal PX PF00787.19 KKK24622.1 - 8.1e-22 77.1 0.6 2e-21 75.8 0.4 1.7 1 0 0 1 1 1 1 PX domain RGS PF00615.14 KKK24622.1 - 7.6e-12 45.3 0.1 1.9e-11 44.0 0.1 1.7 1 0 0 1 1 1 1 Regulator of G protein signaling domain DUF2360 PF10152.4 KKK24622.1 - 0.29 11.4 4.2 0.76 10.0 0.2 2.7 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) Mucin PF01456.12 KKK24622.1 - 2.7 7.7 20.7 6.7 6.4 14.4 1.6 1 0 0 1 1 1 0 Mucin-like glycoprotein PEMT PF04191.8 KKK24623.1 - 2.3e-32 111.2 3.3 2.7e-32 111.0 1.1 1.9 2 0 0 2 2 2 1 Phospholipid methyltransferase YrhK PF14145.1 KKK24623.1 - 0.073 12.7 0.7 0.073 12.7 0.5 2.1 3 0 0 3 3 3 0 YrhK-like protein MtrF PF09472.5 KKK24623.1 - 2.8 7.2 0.0 2.8 7.2 0.0 3.0 3 1 1 4 4 4 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) DUF1218 PF06749.7 KKK24623.1 - 9.6 6.7 6.6 2.9 8.4 0.2 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1218) Yae1_N PF09811.4 KKK24624.1 - 1.1e-07 31.2 3.5 1.7e-07 30.6 2.4 1.3 1 0 0 1 1 1 1 Essential protein Yae1, N terminal ICE2 PF08426.5 KKK24625.1 - 2.4e-144 480.9 13.9 2.8e-144 480.7 9.6 1.0 1 0 0 1 1 1 1 ICE2 FTHFS PF01268.14 KKK24625.1 - 0.2 9.6 0.0 0.28 9.1 0.0 1.1 1 0 0 1 1 1 0 Formate--tetrahydrofolate ligase DUF1517 PF07466.6 KKK24625.1 - 2.6 6.9 5.1 15 4.4 1.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1517) ADH_zinc_N PF00107.21 KKK24628.1 - 3.2e-29 101.1 1.4 6e-29 100.2 1.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KKK24628.1 - 2.3e-09 38.1 0.2 5.6e-09 36.9 0.1 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KKK24628.1 - 2.6e-07 30.3 0.0 3.1e-06 26.9 0.0 2.6 3 0 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.16 KKK24628.1 - 0.0046 16.5 0.4 0.0099 15.4 0.3 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Clr5 PF14420.1 KKK24629.1 - 6.3e-13 48.4 0.8 1e-12 47.7 0.6 1.3 1 0 0 1 1 1 1 Clr5 domain SNF2_N PF00176.18 KKK24630.1 - 1.2e-74 250.8 0.7 2e-74 250.1 0.5 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KKK24630.1 - 1.2e-14 53.8 0.1 3.2e-14 52.5 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KKK24630.1 - 2.5e-08 33.9 0.0 8.9e-08 32.1 0.0 2.0 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 KKK24630.1 - 5.2e-06 26.0 0.0 2.5e-05 23.8 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase HSA PF07529.8 KKK24630.1 - 0.00032 20.4 8.9 0.00032 20.4 6.2 2.6 2 0 0 2 2 2 1 HSA DEAD_2 PF06733.10 KKK24630.1 - 0.047 13.0 0.0 0.1 12.0 0.0 1.5 1 0 0 1 1 1 0 DEAD_2 FUSC PF04632.7 KKK24630.1 - 1.7 6.9 1.4 3.4 5.9 1.0 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family NDUF_B8 PF05821.6 KKK24631.1 - 4.6e-08 32.9 0.0 5.5e-08 32.6 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) Membr_traf_MHD PF10540.4 KKK24632.1 - 5.2e-32 110.4 0.4 2.2e-31 108.4 0.0 2.4 2 0 0 2 2 2 1 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.25 KKK24632.1 - 3.2e-15 55.7 0.0 8.3e-15 54.4 0.0 1.8 1 0 0 1 1 1 1 C2 domain DUF810 PF05664.6 KKK24632.1 - 1.3e-06 26.9 5.9 4.7e-06 25.1 2.3 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF810) EF-hand_2 PF09068.6 KKK24632.1 - 0.031 14.3 0.3 0.41 10.7 0.0 2.9 2 0 0 2 2 2 0 EF hand Zds_C PF08632.5 KKK24647.1 - 3.3e-31 106.4 1.0 5.8e-31 105.6 0.7 1.4 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term SNARE PF05739.14 KKK24647.1 - 0.092 12.4 0.7 0.41 10.3 0.3 2.3 2 0 0 2 2 2 0 SNARE domain OPT PF03169.10 KKK24648.1 - 9.9e-152 506.5 52.5 1.1e-151 506.3 36.4 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Arrestin_C PF02752.17 KKK24649.1 - 1.9e-18 66.8 0.0 4.1e-18 65.7 0.0 1.6 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 KKK24649.1 - 1.2e-15 57.5 0.0 2.5e-15 56.6 0.0 1.5 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.2 KKK24649.1 - 0.0009 18.7 0.0 0.0029 17.1 0.0 1.8 2 0 0 2 2 2 1 Arrestin_N terminal like Miro PF08477.8 KKK24650.1 - 1.3e-37 128.8 0.0 1.8e-18 67.1 0.0 2.4 2 0 0 2 2 2 2 Miro-like protein EF_assoc_2 PF08356.7 KKK24650.1 - 2.1e-34 117.1 0.0 4e-34 116.2 0.0 1.5 1 0 0 1 1 1 1 EF hand associated EF_assoc_1 PF08355.7 KKK24650.1 - 1.3e-31 107.6 0.1 2.2e-31 106.9 0.1 1.4 1 0 0 1 1 1 1 EF hand associated Ras PF00071.17 KKK24650.1 - 9.9e-26 90.0 0.0 5e-14 51.9 0.0 2.2 2 0 0 2 2 2 2 Ras family MMR_HSR1 PF01926.18 KKK24650.1 - 4.6e-11 42.6 0.0 0.00017 21.5 0.0 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase EF-hand_1 PF00036.27 KKK24650.1 - 1.2e-05 24.2 1.4 0.015 14.5 0.1 2.7 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 KKK24650.1 - 3.3e-05 23.9 0.3 0.016 15.3 0.1 2.7 2 0 0 2 2 2 1 EF-hand domain pair AAA_22 PF13401.1 KKK24650.1 - 6.6e-05 23.0 0.5 1.1 9.3 0.0 3.1 2 1 1 3 3 3 2 AAA domain AAA_16 PF13191.1 KKK24650.1 - 0.00011 22.2 3.0 0.22 11.4 0.0 2.9 3 0 0 3 3 3 2 AAA ATPase domain EF-hand_8 PF13833.1 KKK24650.1 - 0.00011 21.6 0.7 0.03 13.9 0.0 2.6 2 0 0 2 2 2 1 EF-hand domain pair AAA_28 PF13521.1 KKK24650.1 - 0.00014 21.8 0.1 0.069 13.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain Dynamin_N PF00350.18 KKK24650.1 - 0.00018 21.3 2.1 0.49 10.2 0.2 3.2 3 1 1 4 4 3 2 Dynamin family EF-hand_6 PF13405.1 KKK24650.1 - 0.0005 19.7 1.6 0.067 13.1 0.1 2.7 2 0 0 2 2 2 1 EF-hand domain AAA_10 PF12846.2 KKK24650.1 - 0.00058 19.3 0.0 0.14 11.6 0.0 2.8 3 0 0 3 3 3 1 AAA-like domain AAA_29 PF13555.1 KKK24650.1 - 0.0011 18.4 0.3 0.72 9.4 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain MobB PF03205.9 KKK24650.1 - 0.0016 18.1 0.1 0.23 11.1 0.1 2.4 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B FtsK_SpoIIIE PF01580.13 KKK24650.1 - 0.0017 17.8 0.0 0.48 9.8 0.0 2.7 3 0 0 3 3 3 1 FtsK/SpoIIIE family RNA_helicase PF00910.17 KKK24650.1 - 0.0032 17.6 0.0 0.96 9.6 0.0 2.7 2 0 0 2 2 2 1 RNA helicase ABC_tran PF00005.22 KKK24650.1 - 0.0034 17.6 0.0 2.4 8.4 0.0 2.5 2 0 0 2 2 2 1 ABC transporter Viral_helicase1 PF01443.13 KKK24650.1 - 0.0039 16.7 0.3 0.092 12.2 0.0 2.7 2 1 0 2 2 2 1 Viral (Superfamily 1) RNA helicase GTP_EFTU PF00009.22 KKK24650.1 - 0.0047 16.3 0.2 0.71 9.2 0.0 2.8 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 KKK24650.1 - 0.0052 15.9 0.2 1.8 7.7 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_24 PF13479.1 KKK24650.1 - 0.0097 15.5 0.1 0.16 11.5 0.1 2.2 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 KKK24650.1 - 0.01 15.5 0.1 5.9 6.5 0.0 2.7 2 0 0 2 2 2 0 NACHT domain AAA_25 PF13481.1 KKK24650.1 - 0.011 15.1 0.1 2.7 7.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 KKK24650.1 - 0.018 14.8 0.0 5.2 6.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain cobW PF02492.14 KKK24650.1 - 0.022 14.1 3.5 0.34 10.3 0.2 3.8 4 1 0 4 4 4 0 CobW/HypB/UreG, nucleotide-binding domain Septin PF00735.13 KKK24650.1 - 0.023 13.7 0.0 0.77 8.7 0.0 2.4 2 0 0 2 2 2 0 Septin Arch_ATPase PF01637.13 KKK24650.1 - 0.023 14.3 0.2 2.1 7.9 0.0 2.9 2 1 1 3 3 3 0 Archaeal ATPase AAA_18 PF13238.1 KKK24650.1 - 0.033 14.4 0.0 6.7 7.0 0.0 2.7 2 1 0 2 2 2 0 AAA domain DUF815 PF05673.8 KKK24650.1 - 0.047 12.6 0.2 1.7 7.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) ATP_bind_1 PF03029.12 KKK24650.1 - 0.048 13.2 1.7 16 4.9 0.0 3.5 4 0 0 4 4 4 0 Conserved hypothetical ATP binding protein AAA_17 PF13207.1 KKK24650.1 - 0.049 14.4 0.0 17 6.2 0.0 2.7 2 0 0 2 2 2 0 AAA domain EF-hand_5 PF13202.1 KKK24650.1 - 0.078 12.3 3.5 0.6 9.5 0.2 2.6 2 0 0 2 2 2 0 EF hand EF-hand_10 PF14788.1 KKK24650.1 - 0.078 12.6 0.4 1.2 8.8 0.1 2.6 2 0 0 2 2 2 0 EF hand AAA PF00004.24 KKK24650.1 - 0.079 13.1 0.9 12 6.1 0.0 3.4 4 1 0 4 4 3 0 ATPase family associated with various cellular activities (AAA) Nuc_deoxyrib_tr PF05014.10 KKK24650.1 - 0.12 12.2 0.0 0.38 10.6 0.0 1.8 1 0 0 1 1 1 0 Nucleoside 2-deoxyribosyltransferase AAA_5 PF07728.9 KKK24650.1 - 0.14 11.8 0.5 26 4.5 0.0 3.1 2 1 1 3 3 3 0 AAA domain (dynein-related subfamily) IIGP PF05049.8 KKK24650.1 - 0.15 10.8 0.8 1.3 7.8 0.0 2.1 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) WD40 PF00400.27 KKK24651.1 - 1.1e-20 72.6 5.6 1.1e-05 25.1 0.1 5.4 5 0 0 5 5 5 4 WD domain, G-beta repeat IKI3 PF04762.7 KKK24651.1 - 0.00013 19.9 0.0 0.0013 16.6 0.0 1.8 1 1 1 2 2 2 1 IKI3 family eIF2A PF08662.6 KKK24651.1 - 0.00083 19.1 0.1 0.023 14.3 0.0 2.2 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 KKK24651.1 - 0.025 12.8 0.0 0.072 11.3 0.0 1.6 2 0 0 2 2 2 0 Cytochrome D1 heme domain DUF500 PF04366.7 KKK24652.1 - 3.2e-44 149.4 0.2 6.4e-44 148.4 0.2 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF500) SH3_1 PF00018.23 KKK24652.1 - 1.5e-13 49.8 0.3 4.7e-13 48.2 0.1 1.9 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 KKK24652.1 - 4.4e-12 45.3 0.1 1.2e-11 44.0 0.1 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KKK24652.1 - 3.1e-11 42.5 0.4 7.2e-11 41.4 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain EMP24_GP25L PF01105.19 KKK24653.1 - 2.5e-43 147.9 0.0 3e-43 147.6 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD EzrA PF06160.7 KKK24653.1 - 0.052 11.7 0.3 0.068 11.3 0.2 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA APH PF01636.18 KKK24654.1 - 5.2e-24 85.2 0.0 7.1e-24 84.8 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KKK24654.1 - 4.8e-07 29.5 0.0 7.9e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.17 KKK24654.1 - 0.012 14.9 0.1 0.07 12.4 0.0 1.9 2 0 0 2 2 2 0 RIO1 family EcKinase PF02958.15 KKK24654.1 - 0.087 11.9 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase PH PF00169.24 KKK24655.1 - 0.0028 17.8 0.0 0.0064 16.6 0.0 1.7 1 0 0 1 1 1 1 PH domain RskA PF10099.4 KKK24655.1 - 0.013 15.2 3.8 0.028 14.1 2.6 1.5 1 0 0 1 1 1 0 Anti-sigma-K factor rskA RTA1 PF04479.8 KKK24668.1 - 1.4e-50 171.9 9.0 2.2e-50 171.2 6.3 1.2 1 0 0 1 1 1 1 RTA1 like protein Orbi_NS3 PF01616.11 KKK24668.1 - 0.14 11.0 0.1 0.31 9.9 0.1 1.6 1 1 0 1 1 1 0 Orbivirus NS3 XFP_C PF09363.5 KKK24669.1 - 5.8e-07 29.1 0.3 6.5e-07 28.9 0.2 1.0 1 0 0 1 1 1 1 XFP C-terminal domain XFP_N PF09364.5 KKK24670.1 - 4.1e-147 489.6 0.0 1.6e-145 484.4 0.0 2.1 1 1 0 1 1 1 1 XFP N-terminal domain XFP PF03894.10 KKK24670.1 - 1.1e-69 233.5 0.1 1.6e-69 233.0 0.0 1.2 1 0 0 1 1 1 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase XFP_C PF09363.5 KKK24670.1 - 1.1e-23 83.7 0.0 2.1e-23 82.8 0.0 1.4 1 0 0 1 1 1 1 XFP C-terminal domain TPP_enzyme_C PF02775.16 KKK24670.1 - 0.0039 16.7 0.1 0.0084 15.6 0.1 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain SH3_2 PF07653.12 KKK24670.1 - 0.042 13.3 0.1 0.11 11.9 0.1 1.7 1 0 0 1 1 1 0 Variant SH3 domain AAA_16 PF13191.1 KKK24671.1 - 1.1e-05 25.4 2.1 0.00086 19.3 1.5 2.4 1 1 0 1 1 1 1 AAA ATPase domain Arch_ATPase PF01637.13 KKK24671.1 - 0.00036 20.2 0.1 0.00087 19.0 0.0 1.6 1 1 0 1 1 1 1 Archaeal ATPase AAA_25 PF13481.1 KKK24671.1 - 0.0054 16.1 0.1 0.02 14.3 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KKK24671.1 - 0.039 13.6 0.1 0.17 11.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KKK24671.1 - 0.07 13.2 0.1 0.42 10.7 0.2 2.2 2 1 0 2 2 2 0 AAA domain Acetate_kinase PF00871.12 KKK24672.1 - 2.3e-87 293.0 0.0 2.8e-87 292.8 0.0 1.0 1 0 0 1 1 1 1 Acetokinase family AATase PF07247.7 KKK24681.1 - 1.5e-12 46.8 0.0 2.4e-12 46.1 0.0 1.4 1 1 0 1 1 1 1 Alcohol acetyltransferase Fungal_trans_2 PF11951.3 KKK24682.1 - 1.6e-06 27.0 0.0 2.3e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain MmgE_PrpD PF03972.9 KKK24683.1 - 1.3e-100 336.6 1.3 5e-100 334.7 0.9 2.1 1 1 0 1 1 1 1 MmgE/PrpD family Citrate_synt PF00285.16 KKK24684.1 - 2.6e-89 299.4 0.0 3.2e-89 299.1 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase DIT1_PvcA PF05141.7 KKK24685.1 - 3.1e-86 289.1 0.0 4.4e-86 288.6 0.0 1.2 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein AMP-binding PF00501.23 KKK24685.1 - 1.2e-25 89.7 0.0 2e-25 89.0 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Transferase PF02458.10 KKK24685.1 - 2.7e-09 35.9 0.0 0.00022 19.7 0.0 2.5 3 0 0 3 3 3 2 Transferase family PP-binding PF00550.20 KKK24685.1 - 1.1e-08 35.1 0.0 2.5e-08 34.0 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Abhydrolase_3 PF07859.8 KKK24686.1 - 1.6e-46 158.5 0.0 2.2e-46 158.0 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 KKK24686.1 - 6.6e-11 41.6 0.3 1.9e-10 40.1 0.2 1.6 1 1 0 1 1 1 1 Carboxylesterase family AATase PF07247.7 KKK24687.1 - 1.4e-13 50.2 0.0 1e-11 44.0 0.0 2.6 1 1 0 1 1 1 1 Alcohol acetyltransferase Condensation PF00668.15 KKK24687.1 - 0.017 14.0 0.0 0.16 10.7 0.0 2.0 2 0 0 2 2 2 0 Condensation domain F-box-like PF12937.2 KKK24688.1 - 1.6e-07 30.9 3.1 4.4e-05 23.1 0.1 3.1 3 0 0 3 3 3 2 F-box-like F-box PF00646.28 KKK24688.1 - 2.2e-05 23.9 1.7 0.00016 21.1 0.1 2.6 2 0 0 2 2 2 1 F-box domain Metallophos PF00149.23 KKK24689.1 - 4.5e-18 65.3 0.6 1.4e-17 63.7 0.4 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.1 KKK24689.1 - 5.7e-16 58.3 0.2 1.6e-15 56.9 0.1 1.9 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C PhoD PF09423.5 KKK24689.1 - 3.8e-05 22.4 0.1 0.00023 19.8 0.0 1.9 2 0 0 2 2 2 1 PhoD-like phosphatase fn3 PF00041.16 KKK24689.1 - 0.00031 20.8 0.1 0.00099 19.1 0.1 1.8 1 1 0 1 1 1 1 Fibronectin type III domain Ank_2 PF12796.2 KKK24690.1 - 3.3e-81 267.7 6.1 1.1e-14 54.4 0.0 5.1 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 KKK24690.1 - 2.9e-57 187.7 2.0 1.1e-07 31.2 0.0 9.7 10 0 0 10 10 10 9 Ankyrin repeat Ank_4 PF13637.1 KKK24690.1 - 2.4e-55 184.0 0.0 1.5e-09 38.1 0.0 6.9 3 2 5 8 8 8 7 Ankyrin repeats (many copies) Ank_5 PF13857.1 KKK24690.1 - 1.5e-49 164.9 0.2 2e-10 40.5 0.0 7.0 1 1 7 8 8 8 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 KKK24690.1 - 3.1e-45 147.6 0.6 0.00049 20.0 0.0 9.8 10 0 0 10 10 10 9 Ankyrin repeat F-box-like PF12937.2 KKK24690.1 - 0.00011 21.8 0.6 0.00019 21.0 0.4 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KKK24690.1 - 0.011 15.4 0.5 0.018 14.7 0.4 1.3 1 0 0 1 1 1 0 F-box domain DNA_pol_phi PF04931.8 KKK24690.1 - 0.082 10.6 0.1 0.66 7.6 0.0 1.9 1 1 1 2 2 2 0 DNA polymerase phi Glyoxalase_2 PF12681.2 KKK24691.1 - 3.6e-08 33.9 0.0 5e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain Abhydrolase_6 PF12697.2 KKK24692.1 - 1.6e-17 64.1 0.1 4.3e-17 62.7 0.1 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KKK24692.1 - 3.9e-09 36.4 0.0 1.3e-08 34.7 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KKK24692.1 - 5.7e-07 29.2 0.0 1.1e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_1 PF00561.15 KKK24692.1 - 0.00048 19.7 0.0 0.0031 17.1 0.0 2.1 2 1 0 2 2 2 1 alpha/beta hydrolase fold DUF1749 PF08538.5 KKK24692.1 - 0.0059 15.5 0.0 0.0096 14.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Peptidase_C14 PF00656.17 KKK24692.1 - 0.017 14.8 0.0 0.03 14.0 0.0 1.3 1 0 0 1 1 1 0 Caspase domain Abhydrolase_2 PF02230.11 KKK24692.1 - 0.13 11.7 0.0 16 4.8 0.0 2.9 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase Pirin PF02678.11 KKK24693.1 - 5.4e-24 84.1 0.8 1.9e-23 82.3 0.5 1.8 1 1 0 1 1 1 1 Pirin Cupin_2 PF07883.6 KKK24693.1 - 3e-06 26.6 1.3 0.00013 21.4 0.2 2.9 2 1 0 2 2 2 1 Cupin domain MFS_1 PF07690.11 KKK24694.1 - 5.6e-15 54.9 52.6 2e-13 49.8 35.3 2.5 1 1 0 1 1 1 1 Major Facilitator Superfamily LacAB_rpiB PF02502.13 KKK24694.1 - 8.9 5.9 6.5 0.89 9.1 0.1 2.3 2 1 0 2 2 2 0 Ribose/Galactose Isomerase MmgE_PrpD PF03972.9 KKK24695.1 - 9.2e-32 109.7 0.0 1.6e-29 102.3 0.0 2.0 1 1 1 2 2 2 2 MmgE/PrpD family Sua5_yciO_yrdC PF01300.13 KKK24696.1 - 1.5e-14 53.6 0.0 2.1e-14 53.1 0.0 1.2 1 0 0 1 1 1 1 Telomere recombination DUF3848 PF12959.2 KKK24698.1 - 0.046 13.6 0.0 0.085 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3848) Polysacc_deac_1 PF01522.16 KKK24714.1 - 2.7e-28 98.0 0.0 7e-28 96.7 0.0 1.7 2 0 0 2 2 2 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.14 KKK24714.1 - 1.4e-06 28.1 44.8 0.0006 19.7 10.9 2.7 2 0 0 2 2 2 2 Chitin recognition protein HEAT_2 PF13646.1 KKK24715.1 - 1e-06 28.8 0.3 4.5e-05 23.6 0.0 3.0 2 1 0 2 2 2 1 HEAT repeats HEAT PF02985.17 KKK24715.1 - 4.7e-06 26.2 1.5 0.09 12.9 0.0 4.1 4 0 0 4 4 4 1 HEAT repeat Adaptin_N PF01602.15 KKK24715.1 - 0.022 13.1 0.1 13 3.9 0.0 2.9 2 1 1 3 3 3 0 Adaptin N terminal region DUF2435 PF10363.4 KKK24715.1 - 0.026 14.4 0.0 0.061 13.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2435) UME PF08064.8 KKK24715.1 - 0.032 14.1 0.0 2.2 8.2 0.0 2.5 2 0 0 2 2 2 0 UME (NUC010) domain DRIM PF07539.7 KKK24715.1 - 0.039 13.3 0.0 0.1 11.9 0.0 1.8 1 1 0 1 1 1 0 Down-regulated in metastasis Cnd1 PF12717.2 KKK24715.1 - 0.059 13.2 0.0 1 9.2 0.0 2.5 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.2 KKK24715.1 - 0.065 13.6 0.0 0.21 11.9 0.0 1.9 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 KKK24715.1 - 0.12 12.8 6.3 10 6.7 0.0 4.8 4 2 3 7 7 7 0 HEAT-like repeat IL13 PF03487.8 KKK24715.1 - 2.5 7.8 5.0 0.58 9.9 0.2 2.4 3 0 0 3 3 3 0 Interleukin-13 OPT PF03169.10 KKK24716.1 - 6.1e-172 573.3 55.8 6.9e-172 573.1 38.7 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DAO PF01266.19 KKK24718.1 - 3.3e-21 75.6 0.1 2.6e-20 72.6 0.1 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KKK24718.1 - 0.079 12.9 0.7 0.21 11.6 0.5 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.15 KKK24718.1 - 0.085 12.9 0.0 0.98 9.5 0.0 2.1 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase ApbA PF02558.11 KKK24718.1 - 0.095 12.1 1.0 0.17 11.2 0.7 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox_2 PF07992.9 KKK24718.1 - 0.096 12.5 0.1 0.15 11.9 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF604 PF04646.7 KKK24718.1 - 0.15 11.2 0.4 0.25 10.5 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF604 Sugar_tr PF00083.19 KKK24719.1 - 2.3e-113 379.1 21.1 2.7e-113 378.9 14.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KKK24719.1 - 6.9e-26 90.7 31.4 8.5e-25 87.1 12.7 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KKK24719.1 - 9e-06 24.3 9.8 6.9e-05 21.4 0.8 3.3 4 0 0 4 4 4 2 MFS/sugar transport protein Transglut_core PF01841.14 KKK24720.1 - 1.5e-11 44.5 0.0 2.6e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 Transglutaminase-like superfamily DUF553 PF04473.7 KKK24720.1 - 0.019 14.2 0.0 0.038 13.2 0.0 1.4 1 0 0 1 1 1 0 Transglutaminase-like domain Tox-PL PF15644.1 KKK24720.1 - 0.073 13.8 0.0 0.17 12.6 0.0 1.6 1 0 0 1 1 1 0 Papain fold toxin 1 TRAM_LAG1_CLN8 PF03798.11 KKK24721.1 - 7.1e-37 126.8 19.3 7.1e-37 126.8 13.4 1.6 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.6 KKK24721.1 - 2.6e-22 78.0 0.0 2.6e-22 78.0 0.0 2.1 2 1 0 2 2 2 1 TRAM1-like protein DUF4492 PF14899.1 KKK24721.1 - 0.0059 16.0 0.1 0.015 14.7 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4492) Thioredoxin_4 PF13462.1 KKK24721.1 - 0.023 14.6 0.1 0.038 14.0 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin DUF4470 PF14737.1 KKK24722.1 - 2.7e-24 84.7 0.0 5.6e-24 83.7 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) Clathrin PF00637.15 KKK24724.1 - 7.4e-23 80.7 5.8 1.9e-20 72.9 1.9 2.7 2 1 0 2 2 2 2 Region in Clathrin and VPS VPS11_C PF12451.3 KKK24724.1 - 1.9e-20 72.4 0.1 4.6e-20 71.2 0.0 1.7 1 0 0 1 1 1 1 Vacuolar protein sorting protein 11 C terminal TPR_14 PF13428.1 KKK24724.1 - 0.00051 20.4 0.1 0.41 11.4 0.0 3.6 3 0 0 3 3 2 1 Tetratricopeptide repeat zf-RING_2 PF13639.1 KKK24724.1 - 0.0046 16.7 6.0 0.0097 15.7 4.1 1.5 1 0 0 1 1 1 1 Ring finger domain TPR_11 PF13414.1 KKK24724.1 - 0.0057 16.2 0.6 0.023 14.3 0.1 2.3 2 0 0 2 2 2 1 TPR repeat zf-C3HC4 PF00097.20 KKK24724.1 - 0.013 15.1 2.6 0.027 14.1 1.8 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KKK24724.1 - 0.015 15.4 2.6 0.029 14.4 1.8 1.4 1 0 0 1 1 1 0 RING-H2 zinc finger zf-RING_5 PF14634.1 KKK24724.1 - 0.029 14.1 5.3 0.06 13.0 3.7 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KKK24724.1 - 0.052 13.5 5.4 0.11 12.5 3.7 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) TPR_12 PF13424.1 KKK24724.1 - 0.26 11.2 10.4 0.27 11.1 0.4 4.7 3 2 2 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.1 KKK24724.1 - 0.26 11.1 7.0 0.05 13.3 0.3 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat zf-Apc11 PF12861.2 KKK24724.1 - 0.31 10.8 1.4 0.68 9.8 0.9 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger TPR_16 PF13432.1 KKK24724.1 - 0.59 10.8 3.4 0.57 10.9 0.2 2.5 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 KKK24724.1 - 9.6 6.4 10.9 0.15 12.0 0.2 3.3 4 0 0 4 4 2 0 Tetratricopeptide repeat MRAP PF15183.1 KKK24737.1 - 0.041 13.4 1.4 0.1 12.2 1.0 1.7 1 0 0 1 1 1 0 Melanocortin-2 receptor accessory protein family COX14 PF14880.1 KKK24737.1 - 9.8 5.8 8.1 3.2 7.4 0.8 2.5 2 0 0 2 2 2 0 Cytochrome oxidase c assembly DC_STAMP PF07782.8 KKK24738.1 - 0.012 15.2 0.1 0.012 15.2 0.0 1.2 1 0 0 1 1 1 0 DC-STAMP-like protein STT3 PF02516.9 KKK24738.1 - 0.017 14.0 0.1 0.019 13.9 0.1 1.0 1 0 0 1 1 1 0 Oligosaccharyl transferase STT3 subunit Baculo_E56 PF04639.7 KKK24738.1 - 0.18 10.4 2.4 0.25 9.9 1.7 1.2 1 0 0 1 1 1 0 Baculoviral E56 protein, specific to ODV envelope Somatomedin_B PF01033.12 KKK24739.1 - 0.069 13.1 4.7 0.089 12.7 3.2 1.2 1 0 0 1 1 1 0 Somatomedin B domain Antifungal_pept PF11410.3 KKK24739.1 - 9.2 6.4 10.7 50 4.0 6.3 2.1 1 1 1 2 2 2 0 Antifungal peptide cNMP_binding PF00027.24 KKK24741.1 - 5.8e-44 147.8 0.0 9.5e-23 79.8 0.0 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain 2OG-FeII_Oxy_3 PF13640.1 KKK24742.1 - 1.9e-11 44.3 0.0 3.2e-11 43.6 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 KKK24742.1 - 2.2e-07 30.4 0.0 3.7e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Fork_head PF00250.13 KKK24743.1 - 1.4e-16 60.3 0.1 2.5e-16 59.4 0.0 1.4 1 0 0 1 1 1 1 Fork head domain FHA PF00498.21 KKK24743.1 - 4.8e-05 23.3 0.0 9e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 FHA domain Dicty_REP PF05086.7 KKK24743.1 - 2.3 5.8 6.6 3.3 5.3 4.6 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Glyco_transf_20 PF00982.16 KKK24746.1 - 2e-149 498.0 0.0 2.7e-149 497.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 KKK24746.1 - 4.8e-91 303.8 0.0 7.1e-91 303.2 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase Hydrolase_3 PF08282.7 KKK24746.1 - 0.0011 18.5 0.0 0.58 9.6 0.0 2.2 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.2 KKK24746.1 - 0.087 12.9 0.1 0.73 9.9 0.0 2.3 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase MFS_1 PF07690.11 KKK24747.1 - 2.1e-22 79.3 52.3 3.6e-19 68.6 31.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily PP28 PF10252.4 KKK24748.1 - 2e-30 104.6 16.9 2e-30 104.6 11.7 3.3 2 1 1 3 3 3 2 Casein kinase substrate phosphoprotein PP28 zf-C4H2 PF10146.4 KKK24748.1 - 0.0053 16.8 2.9 0.0053 16.8 2.0 2.2 2 0 0 2 2 2 1 Zinc finger-containing protein CAF-1_p150 PF11600.3 KKK24748.1 - 1 8.6 28.6 0.14 11.5 6.2 2.3 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF4611 PF15387.1 KKK24748.1 - 2.7 8.1 12.6 2.6 8.2 4.2 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) CENP-B_dimeris PF09026.5 KKK24748.1 - 9.3 6.5 17.6 4.8 7.4 7.3 2.5 2 0 0 2 2 2 0 Centromere protein B dimerisation domain PLDc PF00614.17 KKK24750.1 - 7.7e-15 54.1 0.5 1.6e-07 30.8 0.1 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.1 KKK24750.1 - 1.2e-11 44.4 0.0 1.2e-06 28.3 0.0 2.8 2 0 0 2 2 2 2 PLD-like domain PX PF00787.19 KKK24750.1 - 1.7e-07 31.0 1.5 2.8e-07 30.3 0.0 2.2 3 0 0 3 3 3 1 PX domain PAP_assoc PF03828.14 KKK24751.1 - 0.055 13.4 0.0 1.6 8.7 0.0 2.9 2 1 0 2 2 2 0 Cid1 family poly A polymerase SelB-wing_1 PF09105.5 KKK24751.1 - 0.09 12.4 0.0 0.24 11.1 0.0 1.7 1 0 0 1 1 1 0 Elongation factor SelB, winged helix Fungal_trans PF04082.13 KKK24753.1 - 9.3e-24 83.6 0.1 1.4e-23 83.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain MR_MLE_C PF13378.1 KKK24754.1 - 8.5e-20 70.7 0.0 1.7e-19 69.8 0.0 1.5 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE PF01188.16 KKK24754.1 - 1.1e-11 45.0 0.0 2.4e-11 44.0 0.0 1.6 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MR_MLE_N PF02746.11 KKK24754.1 - 1.2e-10 41.4 0.0 2e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain L51_S25_CI-B8 PF05047.11 KKK24780.1 - 9.7e-22 76.4 0.0 1.4e-21 75.9 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain DUF1751 PF08551.5 KKK24781.1 - 2.3e-29 101.6 2.9 2.3e-29 101.6 2.0 2.0 2 0 0 2 2 2 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.17 KKK24781.1 - 1.8e-06 28.0 10.4 3.2e-06 27.2 7.2 1.3 1 0 0 1 1 1 1 Rhomboid family DUF4149 PF13664.1 KKK24781.1 - 1.6 8.8 10.9 0.3 11.1 1.2 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4149) WD40 PF00400.27 KKK24782.1 - 3.4e-11 42.5 10.7 0.00055 19.7 0.0 7.0 8 0 0 8 8 8 3 WD domain, G-beta repeat LisH PF08513.6 KKK24782.1 - 9.6e-07 28.3 0.0 1.9e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 LisH eIF2A PF08662.6 KKK24782.1 - 0.00026 20.7 0.0 0.0015 18.2 0.0 2.1 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A RhoGEF PF00621.15 KKK24785.1 - 1.7e-23 83.4 0.0 3.6e-23 82.3 0.0 1.6 1 0 0 1 1 1 1 RhoGEF domain DUF3507 PF12015.3 KKK24785.1 - 3.9e-08 33.0 0.0 6.7e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3507) RhoGAP PF00620.22 KKK24785.1 - 0.051 13.1 0.1 5 6.7 0.0 2.7 2 0 0 2 2 2 0 RhoGAP domain Sec7 PF01369.15 KKK24786.1 - 2.3e-58 196.9 0.0 3.9e-58 196.2 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 KKK24786.1 - 1.8e-17 63.2 0.0 3.5e-16 59.0 0.0 2.4 1 1 0 1 1 1 1 Guanine nucleotide exchange factor in Golgi transport N-terminal PUF PF00806.14 KKK24850.1 - 7.4e-54 176.3 2.5 2.7e-08 32.8 0.0 7.5 7 0 0 7 7 7 7 Pumilio-family RNA binding repeat TylF PF05711.6 KKK24850.1 - 0.067 12.2 0.1 0.13 11.3 0.0 1.4 1 0 0 1 1 1 0 Macrocin-O-methyltransferase (TylF) ORC5_C PF14630.1 KKK24851.1 - 3.3e-94 315.3 0.0 4.2e-94 315.0 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_16 PF13191.1 KKK24851.1 - 1.5e-13 51.1 0.1 3.2e-13 50.0 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain WD40 PF00400.27 KKK24871.1 - 1.6e-52 173.5 31.0 2.7e-12 46.0 0.0 12.4 13 0 0 13 13 13 8 WD domain, G-beta repeat Utp12 PF04003.7 KKK24871.1 - 5.2e-28 97.1 0.0 7.9e-28 96.5 0.0 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family eIF2A PF08662.6 KKK24871.1 - 1.3e-06 28.2 0.2 0.0021 17.8 0.1 4.9 5 1 0 5 5 5 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 KKK24871.1 - 5.9e-06 24.6 6.2 0.074 11.1 0.0 4.7 1 1 2 4 4 4 3 Nucleoporin Nup120/160 Nbas_N PF15492.1 KKK24871.1 - 0.024 13.7 0.1 9.1 5.2 0.0 3.2 3 1 0 3 3 3 0 Neuroblastoma-amplified sequence, N terminal AMP-binding_C PF13193.1 KKK24871.1 - 0.026 15.4 0.2 0.056 14.3 0.2 1.5 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain DUF1513 PF07433.6 KKK24871.1 - 0.062 12.1 0.4 1.4 7.7 0.0 3.1 2 2 2 4 4 4 0 Protein of unknown function (DUF1513) Septin PF00735.13 KKK24872.1 - 1.5e-70 237.4 0.0 1.7e-70 237.2 0.0 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 KKK24872.1 - 1.2e-07 31.6 0.0 1.6e-07 31.2 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KKK24872.1 - 1.3e-06 27.9 0.7 5.1e-06 26.0 0.2 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 KKK24872.1 - 9e-06 24.9 0.1 1.6e-05 24.1 0.1 1.4 1 1 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 KKK24872.1 - 0.00087 19.1 0.7 0.29 10.9 0.1 2.2 1 1 1 2 2 2 2 Dynamin family AAA_22 PF13401.1 KKK24872.1 - 0.0012 19.0 0.0 0.0022 18.1 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.1 KKK24872.1 - 0.0013 18.3 0.0 0.0017 17.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain IIGP PF05049.8 KKK24872.1 - 0.003 16.4 0.0 0.0039 16.0 0.0 1.2 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) Miro PF08477.8 KKK24872.1 - 0.0031 17.9 0.1 0.0038 17.7 0.1 1.4 1 1 0 1 1 1 1 Miro-like protein AIG1 PF04548.11 KKK24872.1 - 0.0042 16.2 0.0 0.0053 15.8 0.0 1.2 1 0 0 1 1 1 1 AIG1 family FtsK_SpoIIIE PF01580.13 KKK24872.1 - 0.0048 16.4 0.0 0.0076 15.7 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family Pox_A32 PF04665.7 KKK24872.1 - 0.0072 15.6 0.1 0.011 14.9 0.1 1.2 1 0 0 1 1 1 1 Poxvirus A32 protein PduV-EutP PF10662.4 KKK24872.1 - 0.0099 15.3 0.3 0.9 9.0 0.2 2.5 2 1 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Arch_ATPase PF01637.13 KKK24872.1 - 0.013 15.2 0.0 0.018 14.7 0.0 1.1 1 0 0 1 1 1 0 Archaeal ATPase Ras PF00071.17 KKK24872.1 - 0.019 14.3 0.5 0.042 13.2 0.4 1.5 1 1 0 1 1 1 0 Ras family NACHT PF05729.7 KKK24872.1 - 0.019 14.5 0.0 0.031 13.9 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_23 PF13476.1 KKK24872.1 - 0.024 14.9 0.0 0.029 14.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 KKK24872.1 - 0.03 14.6 0.0 0.04 14.2 0.0 1.3 1 0 0 1 1 1 0 ABC transporter ATP_bind_1 PF03029.12 KKK24872.1 - 0.034 13.6 0.6 4.3 6.8 0.1 2.2 1 1 0 2 2 2 0 Conserved hypothetical ATP binding protein T2SE PF00437.15 KKK24872.1 - 0.035 12.9 0.1 0.054 12.3 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein KAP_NTPase PF07693.9 KKK24872.1 - 0.04 12.9 0.0 0.04 12.9 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain Sigma54_activat PF00158.21 KKK24872.1 - 0.049 13.1 0.0 0.073 12.5 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_10 PF12846.2 KKK24872.1 - 0.066 12.6 0.0 0.076 12.4 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain RNA_helicase PF00910.17 KKK24872.1 - 0.075 13.2 0.0 0.15 12.2 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_16 PF13191.1 KKK24872.1 - 0.082 12.8 0.0 0.1 12.5 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain Gtr1_RagA PF04670.7 KKK24872.1 - 0.082 12.0 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region FeoB_N PF02421.13 KKK24872.1 - 0.16 11.2 0.2 0.59 9.4 0.1 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B HMG_box PF00505.14 KKK24882.1 - 1.2e-21 76.7 1.0 2.1e-21 75.9 0.7 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KKK24882.1 - 3.8e-06 27.1 0.1 8.5e-06 26.0 0.1 1.6 1 0 0 1 1 1 1 HMG-box domain DUF1014 PF06244.7 KKK24882.1 - 0.0024 18.0 0.0 0.0067 16.6 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1014) SAICAR_synt PF01259.13 KKK24883.1 - 2.1e-85 285.8 0.0 2.6e-85 285.5 0.0 1.1 1 0 0 1 1 1 1 SAICAR synthetase RhoGAP PF00620.22 KKK24884.1 - 2.3e-48 163.6 0.0 9.8e-48 161.6 0.0 2.0 2 0 0 2 2 2 1 RhoGAP domain FCH PF00611.18 KKK24884.1 - 1.1e-13 51.2 1.6 2.4e-13 50.0 0.0 2.4 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain DUF953 PF06110.6 KKK24885.1 - 3.1e-14 52.4 0.0 3.6e-14 52.2 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Thioredoxin_9 PF14595.1 KKK24885.1 - 0.00035 20.1 0.0 0.00045 19.7 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin HyaE PF07449.6 KKK24885.1 - 0.011 15.5 0.0 0.021 14.7 0.0 1.6 1 1 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Peptidase_M49 PF03571.10 KKK24886.1 - 1.1e-162 541.9 0.0 1.3e-162 541.7 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M49 MFS_1 PF07690.11 KKK24888.1 - 1.6e-37 129.1 38.7 1.6e-37 129.1 26.8 1.8 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KKK24888.1 - 2.2e-15 55.9 15.8 4e-15 55.0 11.0 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 KKK24888.1 - 6.3e-14 51.4 12.2 6.3e-14 51.4 8.5 2.5 2 0 0 2 2 2 1 Sugar (and other) transporter DSBA PF01323.15 KKK24889.1 - 9.1e-14 51.4 0.0 1.1e-13 51.2 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain DUF2854 PF11016.3 KKK24889.1 - 0.14 11.6 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2854) Glyco_hydro_18 PF00704.23 KKK24890.1 - 9.8e-48 163.3 0.2 1e-46 160.0 0.1 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.14 KKK24890.1 - 1.6e-07 31.1 21.3 3e-07 30.3 14.8 1.4 1 0 0 1 1 1 1 Chitin recognition protein LytR_C PF13399.1 KKK24890.1 - 0.025 14.9 0.1 0.048 14.0 0.0 1.5 1 0 0 1 1 1 0 LytR cell envelope-related transcriptional attenuator ANTH PF07651.11 KKK24892.1 - 4.4e-71 238.8 0.0 4.4e-71 238.8 0.0 2.9 2 1 0 3 3 3 1 ANTH domain I_LWEQ PF01608.12 KKK24892.1 - 1.8e-64 216.3 9.2 1.8e-64 216.3 6.4 5.7 3 2 4 7 7 7 1 I/LWEQ domain COX6A PF02046.10 KKK24893.1 - 2.5e-40 136.9 0.7 3e-40 136.7 0.5 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa RRM_1 PF00076.17 KKK24895.1 - 0.00025 20.5 0.0 0.00047 19.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KKK24895.1 - 0.00026 20.7 0.0 0.00046 19.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KKK24895.1 - 0.015 15.2 0.0 0.026 14.4 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Macoilin PF09726.4 KKK24895.1 - 0.092 11.0 0.0 0.14 10.4 0.0 1.3 1 1 0 1 1 1 0 Transmembrane protein Fungal_trans PF04082.13 KKK24896.1 - 4.7e-22 78.1 0.0 9e-22 77.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK24896.1 - 2.3e-06 27.3 9.4 4.1e-06 26.6 6.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Tmemb_cc2 PF10267.4 KKK24896.1 - 0.088 11.3 0.0 0.13 10.7 0.0 1.2 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein UPF0139 PF03669.8 KKK24897.1 - 0.00056 19.3 0.8 0.00074 19.0 0.6 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0139) Med12 PF09497.5 KKK24898.1 - 6.7e-27 93.2 2.3 1.1e-26 92.6 0.5 2.3 2 0 0 2 2 2 1 Transcription mediator complex subunit Med12 EOS1 PF12326.3 KKK24899.1 - 5.1e-30 104.0 15.3 1.3e-25 89.7 5.9 2.2 1 1 1 2 2 2 2 N-glycosylation protein Pol_alpha_B_N PF08418.5 KKK24899.1 - 0.27 10.7 2.1 0.38 10.2 1.4 1.1 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal SUI1 PF01253.17 KKK24900.1 - 1.4e-29 101.6 6.0 1.9e-29 101.3 4.2 1.1 1 0 0 1 1 1 1 Translation initiation factor SUI1 Cas_Csa5 PF09702.5 KKK24900.1 - 0.11 12.6 0.6 0.33 11.0 0.1 1.8 1 1 0 2 2 2 0 CRISPR-associated protein (Cas_Csa5) MBA1 PF07961.6 KKK24901.1 - 0.017 14.0 0.0 0.029 13.1 0.0 1.4 1 1 0 1 1 1 0 MBA1-like protein Ras PF00071.17 KKK24902.1 - 3.6e-55 185.7 0.0 4.1e-55 185.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KKK24902.1 - 7.1e-18 65.2 0.0 9.8e-18 64.7 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KKK24902.1 - 2.3e-07 30.2 0.0 3e-07 29.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KKK24902.1 - 0.0071 15.7 0.0 0.024 14.0 0.0 1.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Fungal_trans PF04082.13 KKK24903.1 - 4.2e-07 29.0 0.0 8.7e-07 28.0 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK24903.1 - 0.012 15.5 1.6 0.012 15.5 1.1 1.8 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_3 PF01494.14 KKK24905.1 - 1.2e-83 281.1 0.2 1.5e-83 280.8 0.2 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 KKK24905.1 - 2.2e-05 23.5 1.1 4.5e-05 22.5 0.5 1.6 1 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KKK24905.1 - 2.9e-05 24.0 0.3 0.00021 21.2 0.0 2.5 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KKK24905.1 - 5.3e-05 22.4 0.1 0.00011 21.4 0.1 1.5 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.19 KKK24905.1 - 0.0001 21.3 0.1 0.00018 20.4 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 KKK24905.1 - 0.00037 19.0 0.2 0.0007 18.1 0.1 1.4 1 0 0 1 1 1 1 HI0933-like protein Lycopene_cycl PF05834.7 KKK24905.1 - 0.002 17.1 0.1 0.0036 16.2 0.1 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein Trp_halogenase PF04820.9 KKK24905.1 - 0.0025 16.5 0.0 0.0045 15.6 0.0 1.4 1 0 0 1 1 1 1 Tryptophan halogenase Pyr_redox_2 PF07992.9 KKK24905.1 - 0.0038 17.1 0.0 0.007 16.2 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KKK24905.1 - 0.0078 16.6 1.5 0.031 14.6 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 KKK24905.1 - 0.0098 15.5 0.5 0.053 13.1 0.1 2.2 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SE PF08491.5 KKK24905.1 - 0.018 13.8 0.0 0.046 12.5 0.0 1.7 1 1 0 1 1 1 0 Squalene epoxidase Peptidase_C41 PF05417.6 KKK24905.1 - 0.019 14.5 0.0 0.042 13.3 0.0 1.5 1 0 0 1 1 1 0 Hepatitis E cysteine protease Pyr_redox_3 PF13738.1 KKK24905.1 - 0.029 14.4 0.2 0.066 13.2 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KKK24905.1 - 0.043 13.5 0.8 0.098 12.4 0.1 2.0 2 0 0 2 2 2 0 FAD-NAD(P)-binding RRM_1 PF00076.17 KKK24906.1 - 3.3e-15 55.4 0.0 7.7e-15 54.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KKK24906.1 - 1.1e-09 38.1 0.0 2e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) MIP-T3 PF10243.4 KKK24906.1 - 0.63 8.4 77.8 0.026 13.0 46.9 2.0 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 Asp-B-Hydro_N PF05279.6 KKK24906.1 - 2 8.2 56.1 2.2 8.0 35.4 2.1 2 0 0 2 2 2 0 Aspartyl beta-hydroxylase N-terminal region UBX PF00789.15 KKK24907.1 - 5.1e-09 36.0 0.0 1e-08 35.0 0.0 1.4 1 0 0 1 1 1 1 UBX domain DUF4366 PF14283.1 KKK24907.1 - 0.18 11.2 0.0 0.18 11.2 0.0 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4366) CDC27 PF09507.5 KKK24907.1 - 1.1 8.4 17.3 1.8 7.6 12.0 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 ABC2_membrane PF01061.19 KKK24908.1 - 5.2e-82 274.0 61.5 1.7e-44 151.4 14.1 3.5 4 0 0 4 4 4 2 ABC-2 type transporter PDR_CDR PF06422.7 KKK24908.1 - 1.3e-38 130.7 6.8 3.8e-35 119.6 0.0 3.8 3 0 0 3 3 3 2 CDR ABC transporter ABC_tran PF00005.22 KKK24908.1 - 7.5e-37 126.6 0.0 1.5e-17 64.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_trans_N PF14510.1 KKK24908.1 - 7.5e-20 70.8 0.1 7.5e-20 70.8 0.0 2.1 2 0 0 2 2 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 KKK24908.1 - 4e-08 32.8 0.2 7.7e-05 22.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 KKK24908.1 - 5.7e-06 25.6 0.1 0.002 17.3 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 KKK24908.1 - 8.4e-06 25.8 1.9 0.00036 20.5 0.2 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.1 KKK24908.1 - 0.00024 20.5 1.8 0.019 14.4 0.2 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_33 PF13671.1 KKK24908.1 - 0.00045 20.0 0.4 0.0078 16.0 0.1 2.4 2 0 0 2 2 2 1 AAA domain cobW PF02492.14 KKK24908.1 - 0.0015 18.0 1.0 0.073 12.5 0.1 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.1 KKK24908.1 - 0.0021 18.2 0.3 1.1 9.4 0.0 2.8 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 KKK24908.1 - 0.0033 17.1 0.9 2.1 7.9 0.1 2.7 2 0 0 2 2 2 2 NACHT domain AAA_18 PF13238.1 KKK24908.1 - 0.0068 16.7 0.1 0.3 11.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KKK24908.1 - 0.0075 16.0 0.6 4 7.2 0.1 2.6 2 0 0 2 2 2 1 Part of AAA domain PDR_assoc PF08370.6 KKK24908.1 - 0.018 14.5 3.2 0.034 13.6 0.2 2.7 2 0 0 2 2 2 0 Plant PDR ABC transporter associated AAA_17 PF13207.1 KKK24908.1 - 0.054 14.3 0.0 0.86 10.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.1 KKK24908.1 - 0.069 13.1 0.0 2 8.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain Miro PF08477.8 KKK24908.1 - 0.069 13.6 0.0 8.5 6.8 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein AAA PF00004.24 KKK24908.1 - 0.12 12.5 0.1 26 5.0 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) SMC_N PF02463.14 KKK24908.1 - 0.17 11.0 0.0 27 3.8 0.0 3.3 3 1 0 3 3 3 0 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.18 KKK24908.1 - 0.18 11.7 0.0 11 6.0 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase Arch_ATPase PF01637.13 KKK24908.1 - 0.21 11.2 0.0 3.8 7.1 0.0 2.2 2 0 0 2 2 2 0 Archaeal ATPase AAA_30 PF13604.1 KKK24908.1 - 0.36 10.3 2.9 5.6 6.4 0.5 2.6 2 1 0 2 2 2 0 AAA domain Fungal_trans PF04082.13 KKK24909.1 - 5.5e-20 71.3 0.1 8.1e-20 70.7 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain CMS1 PF14617.1 KKK24910.1 - 3.8e-60 203.0 7.5 2e-59 200.6 5.3 2.1 1 1 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.24 KKK24910.1 - 3e-05 23.5 0.0 3.4e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Dicty_REP PF05086.7 KKK24910.1 - 0.34 8.6 1.4 0.42 8.3 0.9 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein FRG2 PF15315.1 KKK24910.1 - 0.68 9.8 6.8 1 9.2 4.7 1.3 1 0 0 1 1 1 0 Facioscapulohumeral muscular dystrophy candidate 2 CENP-T PF15511.1 KKK24911.1 - 9.9e-102 341.2 7.5 9.9e-102 341.2 5.2 2.0 3 0 0 3 3 3 1 Centromere kinetochore component CENP-T CENP-S PF15630.1 KKK24911.1 - 7e-09 35.7 0.1 1.2e-08 34.9 0.0 1.4 1 0 0 1 1 1 1 Kinetochore component CENP-S Histone PF00125.19 KKK24911.1 - 1.8e-05 24.7 0.1 3.3e-05 23.9 0.1 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 DUF531 PF04407.7 KKK24911.1 - 0.0051 16.7 0.0 0.0076 16.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF531) CBFD_NFYB_HMF PF00808.18 KKK24911.1 - 0.015 15.3 0.0 0.024 14.6 0.0 1.4 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone SURF1 PF02104.10 KKK24912.1 - 1.9e-68 230.4 0.0 2.5e-68 230.0 0.0 1.1 1 0 0 1 1 1 1 SURF1 family DUF2076 PF09849.4 KKK24913.1 - 6.5e-08 32.9 9.4 7.7e-08 32.6 6.5 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.8 KKK24913.1 - 0.0002 21.2 3.0 0.00037 20.3 1.9 1.6 1 1 1 2 2 2 2 CHCH domain CIA30 PF08547.7 KKK24914.1 - 1.6e-37 128.7 0.0 4.1e-25 88.4 0.0 2.1 2 0 0 2 2 2 2 Complex I intermediate-associated protein 30 (CIA30) Sugar_tr PF00083.19 KKK24915.1 - 2.4e-95 319.7 17.0 2.7e-95 319.6 11.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KKK24915.1 - 2e-21 76.0 49.5 2.7e-19 69.0 15.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KKK24915.1 - 0.00033 19.1 15.8 0.00034 19.1 0.2 2.5 2 1 0 2 2 2 2 MFS/sugar transport protein DUF1228 PF06779.9 KKK24915.1 - 0.00058 19.8 4.4 0.3 11.1 0.1 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF1228) Apc5 PF12862.2 KKK24916.1 - 1.4e-36 124.2 5.1 3.4e-36 122.9 1.5 2.5 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 5 TPR_12 PF13424.1 KKK24916.1 - 0.47 10.4 8.0 8 6.4 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Exo_endo_phos_2 PF14529.1 KKK24917.1 - 9e-14 51.1 0.0 2.4e-13 49.7 0.0 1.8 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 KKK24917.1 - 8e-13 48.8 0.2 1.2e-12 48.3 0.1 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-GRF PF06839.7 KKK24917.1 - 0.016 15.0 1.0 0.038 13.9 0.7 1.7 1 0 0 1 1 1 0 GRF zinc finger adh_short_C2 PF13561.1 KKK24918.1 - 2.2e-32 112.7 0.1 2.7e-32 112.4 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KKK24918.1 - 1.2e-25 90.3 8.4 1.4e-24 86.8 5.8 2.2 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KKK24918.1 - 9.8e-09 35.1 2.8 3.3e-08 33.4 1.9 1.7 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 KKK24918.1 - 0.12 11.7 0.9 0.43 9.9 0.6 1.9 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Fungal_trans PF04082.13 KKK24919.1 - 1e-05 24.5 0.0 0.00027 19.9 0.2 2.3 1 1 1 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK24919.1 - 1.1e-05 25.2 14.2 2.6e-05 24.0 9.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3694 PF12473.3 KKK24919.1 - 0.0074 15.9 0.0 0.016 14.8 0.0 1.5 1 0 0 1 1 1 1 Kinesin protein Trp_syntA PF00290.15 KKK24920.1 - 3.6e-90 300.9 0.0 5.9e-90 300.3 0.0 1.3 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.20 KKK24920.1 - 3.2e-37 128.3 0.2 5.3e-37 127.6 0.2 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Malic_M PF03949.10 KKK24925.1 - 5.3e-86 288.3 0.0 6.8e-86 287.9 0.0 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 KKK24925.1 - 7.4e-47 159.2 0.0 1.9e-36 125.3 0.0 2.3 1 1 1 2 2 2 2 Malic enzyme, N-terminal domain zf-C2H2 PF00096.21 KKK24954.1 - 0.097 13.0 2.6 2 8.9 0.0 3.3 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KKK24954.1 - 0.55 10.6 15.6 0.6 10.5 0.2 3.9 3 0 0 3 3 3 0 C2H2-type zinc finger DUF3500 PF12006.3 KKK24955.1 - 5.8e-105 350.6 0.0 7.5e-105 350.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3500) adh_short PF00106.20 KKK24955.1 - 2.5e-19 69.7 0.6 5.9e-18 65.3 0.4 2.2 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KKK24955.1 - 3.7e-07 29.9 0.2 8.4e-07 28.8 0.0 1.7 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 KKK24955.1 - 0.0045 16.4 0.0 0.007 15.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 KKK24956.1 - 2.8e-22 79.3 2.8 6.3e-22 78.2 2.0 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KKK24956.1 - 2.3e-19 70.1 0.0 2.9e-19 69.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KKK24956.1 - 2.9e-07 30.3 1.0 2e-06 27.5 0.7 2.1 1 1 0 1 1 1 1 KR domain UPF0160 PF03690.8 KKK24957.1 - 3e-118 394.8 0.0 3.4e-118 394.6 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) CTP_synth_N PF06418.9 KKK24958.1 - 3.6e-116 387.0 0.2 4.9e-116 386.6 0.1 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.23 KKK24958.1 - 9.4e-51 172.0 0.1 2.6e-50 170.5 0.0 1.7 2 0 0 2 2 2 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 KKK24958.1 - 1.4e-06 27.9 0.0 2.9e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Peptidase C26 CbiA PF01656.18 KKK24958.1 - 0.0021 17.5 0.0 0.004 16.5 0.0 1.4 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain DUF3535 PF12054.3 KKK24959.1 - 1.5e-138 462.1 0.0 5.6e-138 460.2 0.0 2.0 3 0 0 3 3 3 1 Domain of unknown function (DUF3535) SNF2_N PF00176.18 KKK24959.1 - 7.5e-72 241.6 0.0 1.1e-71 241.1 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HEAT PF02985.17 KKK24959.1 - 9.7e-16 56.3 16.9 0.2 11.8 0.0 10.8 11 0 0 11 11 11 6 HEAT repeat Helicase_C PF00271.26 KKK24959.1 - 2.2e-14 53.0 0.0 5.9e-14 51.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Vac14_Fab1_bd PF12755.2 KKK24959.1 - 4.3e-07 30.2 0.1 0.076 13.3 0.0 4.0 3 1 0 4 4 4 2 Vacuolar 14 Fab1-binding region HEAT_2 PF13646.1 KKK24959.1 - 2e-06 28.0 13.5 0.0044 17.2 0.1 7.1 6 2 1 7 7 7 2 HEAT repeats HEAT_EZ PF13513.1 KKK24959.1 - 0.0018 18.6 19.6 2 8.9 0.0 8.7 9 0 0 9 9 9 1 HEAT-like repeat Cnd1 PF12717.2 KKK24959.1 - 0.014 15.2 0.1 5.4 6.8 0.0 4.5 4 1 1 5 5 5 0 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.3 KKK24959.1 - 0.029 13.7 0.1 5.6 6.2 0.0 3.7 2 1 2 4 4 4 0 CLASP N terminal TPR_11 PF13414.1 KKK24960.1 - 8.1e-06 25.4 12.6 0.00079 19.0 0.8 5.2 5 0 0 5 5 5 2 TPR repeat TPR_7 PF13176.1 KKK24960.1 - 3.1 7.8 6.2 1.6e+02 2.5 0.0 5.0 6 0 0 6 6 6 0 Tetratricopeptide repeat ChAPs PF09295.5 KKK24961.1 - 1.1e-156 521.5 0.0 1.4e-156 521.2 0.0 1.1 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_11 PF13414.1 KKK24961.1 - 1.8e-07 30.7 0.3 0.0043 16.6 0.0 2.5 2 0 0 2 2 2 2 TPR repeat TPR_8 PF13181.1 KKK24961.1 - 0.00021 20.8 0.0 4.2 7.3 0.0 3.6 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 KKK24961.1 - 0.00022 20.9 1.3 0.28 11.1 0.1 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 KKK24961.1 - 0.00024 20.5 0.1 3.5 7.3 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 KKK24961.1 - 0.004 17.2 0.0 0.75 9.9 0.0 3.4 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 KKK24961.1 - 0.013 16.0 7.3 5 8.0 0.0 5.1 3 2 3 6 6 6 0 Tetratricopeptide repeat TPR_12 PF13424.1 KKK24961.1 - 0.015 15.2 1.4 44 4.1 0.0 3.7 3 1 1 4 4 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 KKK24961.1 - 0.026 15.1 0.2 3.3 8.5 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.1 KKK24961.1 - 0.035 14.4 0.6 8.9 6.7 0.0 3.2 2 1 0 3 3 3 0 Tetratricopeptide repeat TPR_15 PF13429.1 KKK24961.1 - 0.043 12.8 1.0 2.6 7.0 0.1 3.0 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 KKK24961.1 - 0.21 11.5 1.2 56 3.8 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat Antimicrobial_8 PF08103.6 KKK24961.1 - 0.8 9.7 2.0 2.1 8.4 0.3 2.4 2 0 0 2 2 2 0 Uperin family UQ_con PF00179.21 KKK24962.1 - 1.7e-41 140.9 0.0 1.9e-41 140.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KKK24962.1 - 7.9e-09 35.3 0.0 1e-08 35.0 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 KKK24962.1 - 0.015 14.9 0.0 0.023 14.3 0.0 1.3 1 0 0 1 1 1 0 UEV domain RWD PF05773.17 KKK24962.1 - 0.086 12.7 0.2 0.12 12.3 0.1 1.4 1 1 0 1 1 1 0 RWD domain Peptidase_S24 PF00717.18 KKK24963.1 - 1.2e-07 31.2 0.0 2e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like Fungal_trans PF04082.13 KKK24964.1 - 1.4e-07 30.6 0.6 3.7e-07 29.2 0.4 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK24964.1 - 1.3e-06 28.1 10.2 2.2e-06 27.4 7.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ERCC4 PF02732.10 KKK24965.1 - 5e-33 113.8 0.0 8.4e-33 113.1 0.0 1.4 1 0 0 1 1 1 1 ERCC4 domain Epimerase PF01370.16 KKK24965.1 - 3.5e-15 56.0 0.0 5.8e-15 55.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KKK24965.1 - 2.5e-06 26.4 0.0 5.5e-06 25.2 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 KKK24965.1 - 0.00024 21.0 0.0 0.0029 17.5 0.0 2.7 2 1 0 2 2 2 1 short chain dehydrogenase NAD_binding_10 PF13460.1 KKK24965.1 - 0.00029 20.8 0.1 0.00055 19.9 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 KKK24965.1 - 0.0003 19.7 0.1 0.27 10.0 0.0 2.6 3 0 0 3 3 3 2 Male sterility protein Ldh_1_N PF00056.18 KKK24965.1 - 0.0057 16.4 0.0 0.01 15.6 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain DapB_N PF01113.15 KKK24965.1 - 0.022 14.7 0.0 0.05 13.5 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus KR PF08659.5 KKK24965.1 - 0.044 13.4 0.0 0.11 12.0 0.0 1.7 1 0 0 1 1 1 0 KR domain DUF4364 PF14277.1 KKK24965.1 - 0.053 13.1 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4364) Polysacc_synt_2 PF02719.10 KKK24965.1 - 0.12 11.2 0.0 0.43 9.4 0.0 1.8 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein KSHV_K1 PF11049.3 KKK24966.1 - 0.097 12.6 0.1 0.18 11.8 0.1 1.5 1 0 0 1 1 1 0 Glycoprotein K1 of Kaposi's sarcoma-associated herpes virus E1-E2_ATPase PF00122.15 KKK24968.1 - 5.2e-53 179.4 0.0 2.2e-52 177.4 0.0 1.9 2 0 0 2 2 2 1 E1-E2 ATPase HMA PF00403.21 KKK24968.1 - 3.3e-42 142.4 0.5 4.9e-10 39.4 0.1 4.4 4 0 0 4 4 4 4 Heavy-metal-associated domain Hydrolase PF00702.21 KKK24968.1 - 5.7e-35 121.6 0.0 1.2e-34 120.6 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KKK24968.1 - 3.2e-18 66.6 0.0 6.5e-18 65.5 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KKK24968.1 - 1.4e-05 24.8 0.0 0.0068 16.0 0.0 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Sugar_tr PF00083.19 KKK24969.1 - 1.9e-75 254.1 20.4 2.7e-75 253.6 14.1 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter TFIIB PF00382.14 KKK24969.1 - 2.6e-32 110.4 0.9 2.7e-17 62.3 0.1 2.6 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.8 KKK24969.1 - 1.1e-26 92.8 1.2 2.5e-26 91.7 0.0 2.3 2 0 0 2 2 2 1 Brf1-like TBP-binding domain MFS_1 PF07690.11 KKK24969.1 - 6.6e-19 67.8 17.9 6.6e-19 67.8 12.4 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Cyclin_N PF00134.18 KKK24969.1 - 2.7e-05 23.7 0.0 0.11 12.0 0.0 2.4 2 0 0 2 2 2 2 Cyclin, N-terminal domain TF_Zn_Ribbon PF08271.7 KKK24969.1 - 0.0018 17.5 2.3 0.0018 17.5 1.6 2.0 2 0 0 2 2 2 1 TFIIB zinc-binding RRN7 PF11781.3 KKK24969.1 - 0.035 13.6 0.2 0.094 12.2 0.1 1.7 1 0 0 1 1 1 0 RNA polymerase I-specific transcription initiation factor Rrn7 IBR PF01485.16 KKK24969.1 - 0.072 12.9 1.2 0.15 11.9 0.8 1.5 1 0 0 1 1 1 0 IBR domain TPT PF03151.11 KKK24970.1 - 1e-26 93.3 16.2 1e-26 93.3 11.3 2.8 2 1 0 3 3 3 1 Triose-phosphate Transporter family UAA PF08449.6 KKK24970.1 - 0.00042 19.3 24.2 0.012 14.5 16.8 2.2 1 1 0 1 1 1 1 UAA transporter family RTA1 PF04479.8 KKK24971.1 - 1.1e-16 61.0 3.5 1.9e-16 60.2 2.4 1.3 1 0 0 1 1 1 1 RTA1 like protein Kinesin PF00225.18 KKK24972.1 - 3.9e-57 193.4 0.0 6.3e-57 192.7 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain KLRAQ PF10205.4 KKK24972.1 - 0.024 14.6 0.9 0.024 14.6 0.6 2.5 1 1 0 2 2 2 0 Predicted coiled-coil domain-containing protein KIAA1430 PF13879.1 KKK24972.1 - 0.037 14.4 5.4 3.5 8.1 1.4 2.8 2 0 0 2 2 2 0 KIAA1430 homologue bZIP_2 PF07716.10 KKK24972.1 - 0.04 13.7 0.8 0.04 13.7 0.5 3.2 3 0 0 3 3 3 0 Basic region leucine zipper DUF837 PF05769.6 KKK24972.1 - 0.11 12.0 8.9 0.68 9.4 6.2 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF837) Herpes_BLRF2 PF05812.7 KKK24972.1 - 0.61 9.9 8.6 5.4 6.8 0.2 2.5 2 0 0 2 2 2 0 Herpesvirus BLRF2 protein Pox_A_type_inc PF04508.7 KKK24972.1 - 1.8 8.5 7.6 0.28 11.0 0.6 2.8 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat NYD-SP28_assoc PF14775.1 KKK24972.1 - 2 8.1 5.4 4.8 6.9 1.0 2.4 2 0 0 2 2 2 0 Sperm tail C-terminal domain DivIC PF04977.10 KKK24972.1 - 3.3 7.2 7.8 15 5.1 1.4 2.9 3 0 0 3 3 3 0 Septum formation initiator Asp_protease PF09668.5 KKK24973.1 - 2.6e-61 204.6 0.1 4.1e-61 204.0 0.1 1.3 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.1 KKK24973.1 - 6.7e-11 42.5 0.0 1.7e-10 41.2 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease ubiquitin PF00240.18 KKK24973.1 - 8.4e-11 41.1 0.0 1.5e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family gag-asp_proteas PF13975.1 KKK24973.1 - 5.2e-06 26.1 0.0 1.4e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease UBA PF00627.26 KKK24973.1 - 6.6e-06 25.8 0.0 1.4e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain RVP_2 PF08284.6 KKK24973.1 - 1.3e-05 25.1 0.0 2.2e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP PF00077.15 KKK24973.1 - 0.00037 20.3 0.0 0.00094 19.0 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease Rad60-SLD PF11976.3 KKK24973.1 - 0.00049 19.7 0.0 0.001 18.6 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA_4 PF14555.1 KKK24973.1 - 0.011 15.2 0.0 0.027 14.0 0.0 1.7 1 0 0 1 1 1 0 UBA-like domain Ubiquitin_2 PF14560.1 KKK24973.1 - 0.067 13.4 0.0 0.13 12.5 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-like domain NAD_binding_7 PF13241.1 KKK24973.1 - 0.088 13.0 0.0 1.2 9.4 0.0 2.3 2 0 0 2 2 2 0 Putative NAD(P)-binding UN_NPL4 PF11543.3 KKK24973.1 - 0.11 12.7 0.0 0.22 11.8 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Cys_Met_Meta_PP PF01053.15 KKK24974.1 - 6e-11 41.2 0.1 7.5e-11 40.9 0.1 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DUF2781 PF10914.3 KKK24975.1 - 1e-39 135.7 7.2 1.2e-39 135.5 5.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) DUF962 PF06127.6 KKK24975.1 - 0.17 11.7 0.6 0.35 10.7 0.1 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF962) Glyco_transf_90 PF05686.7 KKK24987.1 - 6.5e-18 64.6 0.2 8.2e-18 64.2 0.1 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 90 p450 PF00067.17 KKK24988.1 - 1.6e-49 168.7 0.0 3.6e-49 167.5 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 PMP1_2 PF08114.6 KKK25003.1 - 0.0084 15.5 0.3 0.017 14.5 0.2 1.5 1 0 0 1 1 1 1 ATPase proteolipid family zf-LITAF-like PF10601.4 KKK25004.1 - 4.5e-23 80.8 6.9 5.6e-23 80.5 4.8 1.1 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain Zn-ribbon_8 PF09723.5 KKK25004.1 - 0.0051 16.7 0.4 0.065 13.1 0.1 2.2 2 0 0 2 2 2 1 Zinc ribbon domain Lar_restr_allev PF14354.1 KKK25004.1 - 0.19 12.0 7.5 1.3 9.4 5.2 2.0 1 1 0 1 1 1 0 Restriction alleviation protein Lar Zn_Tnp_IS1595 PF12760.2 KKK25004.1 - 1.1 9.1 5.1 20 5.1 3.7 2.2 1 1 1 2 2 2 0 Transposase zinc-ribbon domain NOB1_Zn_bind PF08772.6 KKK25004.1 - 1.7 8.5 6.1 4.8 7.0 0.1 2.2 1 1 1 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like Dispanin PF04505.7 KKK25004.1 - 3.8 7.1 6.5 1.5 8.4 1.6 2.1 1 1 1 2 2 2 0 Interferon-induced transmembrane protein NAD_binding_2 PF03446.10 KKK25005.1 - 6.1e-40 136.7 0.1 1.1e-39 135.8 0.1 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 KKK25005.1 - 1.7e-39 134.6 2.4 2.6e-27 95.3 0.0 2.5 3 0 0 3 3 3 2 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 3HCDH_N PF02737.13 KKK25005.1 - 0.00063 19.4 0.0 0.0014 18.3 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.12 KKK25005.1 - 0.0016 18.8 0.1 0.0069 16.7 0.0 2.1 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Ferritin_2 PF13668.1 KKK25006.1 - 1.8e-05 24.6 0.1 2.7e-05 24.1 0.1 1.2 1 0 0 1 1 1 1 Ferritin-like domain F-box-like PF12937.2 KKK25007.1 - 0.0099 15.5 0.1 0.023 14.4 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KKK25007.1 - 0.033 13.8 0.1 0.074 12.7 0.1 1.6 1 0 0 1 1 1 0 F-box domain F_bP_aldolase PF01116.15 KKK25008.1 - 3e-57 193.9 0.5 5.4e-45 153.7 0.1 2.0 2 0 0 2 2 2 2 Fructose-bisphosphate aldolase class-II PTE PF02126.13 KKK25008.1 - 0.005 15.8 0.3 0.0076 15.3 0.2 1.2 1 0 0 1 1 1 1 Phosphotriesterase family PALP PF00291.20 KKK25008.1 - 0.012 14.9 0.7 0.017 14.3 0.5 1.2 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme Methyltransf_24 PF13578.1 KKK25008.1 - 0.053 14.3 0.1 0.09 13.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Cerato-platanin PF07249.7 KKK25008.1 - 0.089 12.7 0.1 0.18 11.7 0.1 1.5 1 0 0 1 1 1 0 Cerato-platanin Fer2_3 PF13085.1 KKK25009.1 - 1.3e-31 108.6 0.0 2.2e-31 107.9 0.0 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.1 KKK25009.1 - 1.7e-09 37.8 6.1 1.7e-09 37.8 4.2 2.2 3 0 0 3 3 3 1 4Fe-4S dicluster domain Fer4_8 PF13183.1 KKK25009.1 - 7.7e-09 35.4 4.5 7.7e-09 35.4 3.1 1.9 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_9 PF13187.1 KKK25009.1 - 0.00041 20.5 4.1 0.032 14.5 0.4 3.1 3 0 0 3 3 3 1 4Fe-4S dicluster domain Fer4_18 PF13746.1 KKK25009.1 - 0.00044 20.6 2.0 0.00044 20.6 1.4 2.7 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_10 PF13237.1 KKK25009.1 - 0.00046 19.9 4.3 0.00046 19.9 3.0 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.22 KKK25009.1 - 0.0062 16.2 0.2 0.0062 16.2 0.2 2.2 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_7 PF12838.2 KKK25009.1 - 0.018 15.4 6.1 0.018 15.4 4.2 2.5 2 1 0 2 2 2 0 4Fe-4S dicluster domain Fer4_15 PF13459.1 KKK25009.1 - 0.78 10.3 5.0 0.85 10.2 0.1 2.7 3 0 0 3 3 3 0 4Fe-4S single cluster domain Pec_lyase_C PF00544.14 KKK25010.1 - 1.7e-12 47.2 1.7 2.9e-12 46.4 1.2 1.4 1 0 0 1 1 1 1 Pectate lyase RRM_2 PF04059.7 KKK25067.1 - 2.3e-40 136.4 1.0 4.8e-40 135.4 0.4 1.8 2 0 0 2 2 2 1 RNA recognition motif 2 RRM_1 PF00076.17 KKK25067.1 - 4.3e-10 39.0 0.0 0.038 13.6 0.0 3.8 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KKK25067.1 - 0.0024 17.7 0.1 0.67 9.9 0.0 3.4 3 0 0 3 3 3 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KKK25067.1 - 0.016 15.0 0.0 0.23 11.3 0.0 2.5 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TRAPP PF04051.11 KKK25068.1 - 9.9e-46 155.0 0.0 1.1e-45 154.8 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component PINIT PF14324.1 KKK25069.1 - 4.6e-44 149.9 0.1 1e-43 148.8 0.0 1.6 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.15 KKK25069.1 - 2.5e-21 74.8 7.0 4.7e-21 74.0 4.8 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger SAP PF02037.22 KKK25069.1 - 7.6e-08 31.6 1.7 2.7e-07 29.9 0.0 2.6 2 0 0 2 2 2 1 SAP domain zf-Nse PF11789.3 KKK25069.1 - 3.2e-06 26.5 2.1 7.7e-06 25.3 1.4 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit OGFr_III PF04680.8 KKK25069.1 - 0.085 13.0 2.6 0.28 11.3 1.8 1.9 1 0 0 1 1 1 0 Opioid growth factor receptor repeat zf-Sec23_Sec24 PF04810.10 KKK25069.1 - 0.16 11.5 1.7 0.51 9.9 0.7 2.1 1 1 0 1 1 1 0 Sec23/Sec24 zinc finger DUF2423 PF10338.4 KKK25070.1 - 4.9e-20 71.2 2.2 4.9e-20 71.2 1.5 2.0 3 0 0 3 3 3 1 Protein of unknown function (DUF2423) Presenilin PF01080.12 KKK25070.1 - 0.9 8.2 3.2 1 8.1 2.2 1.1 1 0 0 1 1 1 0 Presenilin HMG14_17 PF01101.13 KKK25070.1 - 1.4 9.7 11.8 0.053 14.2 4.0 1.8 1 1 1 2 2 2 0 HMG14 and HMG17 Phosphodiest PF01663.17 KKK25071.1 - 1e-17 64.5 0.7 2.1e-16 60.2 0.5 2.2 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 KKK25071.1 - 8.7e-05 21.8 0.0 0.00032 19.9 0.0 1.8 2 0 0 2 2 2 1 Sulfatase Metalloenzyme PF01676.13 KKK25071.1 - 0.0082 15.5 0.0 0.013 14.8 0.0 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily DUF229 PF02995.12 KKK25071.1 - 0.13 10.6 0.0 0.2 10.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Ldh_1_N PF00056.18 KKK25073.1 - 1.6e-45 154.4 0.1 2.7e-45 153.6 0.0 1.4 2 0 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 KKK25073.1 - 4.1e-39 134.1 0.0 5.4e-39 133.6 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.14 KKK25073.1 - 0.00026 19.8 0.0 0.0004 19.1 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Glyco_hydro_4 PF02056.11 KKK25073.1 - 0.006 15.9 0.0 0.057 12.7 0.0 2.2 1 1 1 2 2 2 1 Family 4 glycosyl hydrolase NAD_binding_10 PF13460.1 KKK25073.1 - 0.0065 16.5 0.1 0.014 15.3 0.0 1.7 1 1 0 1 1 1 1 NADH(P)-binding Semialdhyde_dh PF01118.19 KKK25073.1 - 0.035 14.4 0.0 0.079 13.2 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain CBFD_NFYB_HMF PF00808.18 KKK25074.1 - 5.1e-19 68.0 0.5 8.8e-19 67.3 0.4 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 KKK25074.1 - 1.6e-12 47.3 0.1 2.7e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.5 KKK25074.1 - 0.042 13.6 0.0 0.065 13.0 0.0 1.3 1 0 0 1 1 1 0 CENP-S associating Centromere protein X Sec15 PF04091.7 KKK25075.1 - 1.2e-112 376.2 1.2 1.2e-112 376.2 0.8 2.2 2 1 0 2 2 2 1 Exocyst complex subunit Sec15-like Sec5 PF15469.1 KKK25075.1 - 8.7e-05 22.3 4.6 0.00048 19.9 1.4 2.7 2 0 0 2 2 2 1 Exocyst complex component Sec5 COG2 PF06148.6 KKK25075.1 - 0.0023 17.8 6.8 0.0023 17.8 4.7 2.8 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF2450 PF10475.4 KKK25075.1 - 0.0043 15.9 7.6 0.0043 15.9 5.3 1.7 2 0 0 2 2 2 1 Protein of unknown function N-terminal domain (DUF2450) COG5 PF10392.4 KKK25075.1 - 0.0063 16.4 7.1 0.013 15.4 3.5 2.5 2 0 0 2 2 2 1 Golgi transport complex subunit 5 Gp-FAR-1 PF05823.7 KKK25075.1 - 0.02 14.8 2.0 0.071 13.0 1.4 2.0 1 0 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Vps51 PF08700.6 KKK25075.1 - 0.11 12.4 4.4 0.11 12.3 1.0 2.6 2 0 0 2 2 2 0 Vps51/Vps67 Sec8_exocyst PF04048.9 KKK25075.1 - 0.42 10.2 10.9 0.051 13.2 3.4 2.6 3 0 0 3 3 3 0 Sec8 exocyst complex component specific domain FUSC PF04632.7 KKK25075.1 - 1.5 7.1 5.5 2.4 6.4 3.8 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF4206 PF13901.1 KKK25075.1 - 1.6 8.2 5.4 1.2 8.6 1.2 2.7 3 1 0 3 3 3 0 Domain of unknown function (DUF4206) PNP_UDP_1 PF01048.15 KKK25076.1 - 4.7e-48 163.1 0.1 6.2e-48 162.8 0.1 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily Fcf2 PF08698.6 KKK25077.1 - 1.3e-31 108.4 0.1 2.5e-31 107.6 0.0 1.5 1 1 0 1 1 1 1 Fcf2 pre-rRNA processing NAD_binding_8 PF13450.1 KKK25080.1 - 1.2e-12 47.6 0.0 2.5e-12 46.6 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KKK25080.1 - 0.0035 16.3 0.2 0.038 12.8 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Amino_oxidase PF01593.19 KKK25080.1 - 0.01 14.9 0.1 0.023 13.7 0.1 1.5 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase Pyr_redox PF00070.22 KKK25080.1 - 0.018 15.4 0.1 1.9 8.9 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KKK25080.1 - 0.031 13.2 0.0 0.045 12.6 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_2 PF00890.19 KKK25080.1 - 0.032 13.0 0.0 0.049 12.4 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.1 KKK25080.1 - 0.04 13.6 0.1 0.79 9.4 0.0 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 KKK25080.1 - 0.07 12.1 0.1 0.16 10.9 0.0 1.6 2 0 0 2 2 2 0 FAD binding domain Thi4 PF01946.12 KKK25080.1 - 0.084 11.9 0.0 0.15 11.1 0.0 1.4 1 0 0 1 1 1 0 Thi4 family HATPase_c_3 PF13589.1 KKK25081.1 - 1.1e-17 64.0 0.0 1.9e-17 63.2 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MutL_C PF08676.6 KKK25081.1 - 7.8e-09 35.2 0.0 3.9e-08 32.9 0.0 2.0 2 0 0 2 2 2 1 MutL C terminal dimerisation domain HATPase_c PF02518.21 KKK25081.1 - 0.011 15.4 0.0 0.024 14.3 0.0 1.6 1 1 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase RasGEF PF00617.14 KKK25083.1 - 8.5e-56 188.6 0.5 2.2e-55 187.2 0.1 1.8 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.15 KKK25083.1 - 8.8e-19 67.5 0.0 2.8e-18 65.9 0.0 1.9 2 0 0 2 2 2 1 RasGEF N-terminal motif SH3_9 PF14604.1 KKK25083.1 - 1.8e-06 27.4 0.0 5.3e-06 25.9 0.0 1.9 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KKK25083.1 - 1.2e-05 24.6 0.0 3.3e-05 23.1 0.0 1.9 2 0 0 2 2 2 1 SH3 domain CwfJ_C_1 PF04677.10 KKK25085.1 - 2.2e-30 104.8 0.0 4e-29 100.7 0.0 2.2 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 KKK25085.1 - 3.8e-23 81.8 0.0 2.1e-22 79.4 0.0 2.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 ATP_bind_1 PF03029.12 KKK25086.1 - 4.4e-75 252.2 0.0 6.9e-75 251.6 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.22 KKK25086.1 - 0.00011 21.7 0.0 0.0023 17.4 0.0 2.8 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain ArgK PF03308.11 KKK25086.1 - 0.00082 18.2 0.0 0.014 14.1 0.0 2.3 2 0 0 2 2 2 1 ArgK protein AAA_10 PF12846.2 KKK25086.1 - 0.0097 15.3 0.0 0.017 14.5 0.0 1.5 1 1 0 1 1 1 1 AAA-like domain Methyltransf_32 PF13679.1 KKK25086.1 - 0.015 15.0 0.0 0.19 11.3 0.1 2.4 2 1 0 2 2 2 0 Methyltransferase domain FeoB_N PF02421.13 KKK25086.1 - 0.031 13.5 0.0 0.1 11.9 0.0 1.8 2 0 0 2 2 2 0 Ferrous iron transport protein B Miro PF08477.8 KKK25086.1 - 0.073 13.5 0.0 1.9 8.9 0.0 2.5 2 0 0 2 2 2 0 Miro-like protein CbiA PF01656.18 KKK25086.1 - 0.081 12.3 0.0 0.19 11.1 0.0 1.7 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain NACHT PF05729.7 KKK25086.1 - 0.092 12.3 0.0 0.46 10.1 0.0 2.0 2 0 0 2 2 2 0 NACHT domain Zn_clus PF00172.13 KKK25087.1 - 1.2e-08 34.6 8.6 1.9e-08 34.0 5.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2478 PF10649.4 KKK25087.1 - 0.23 10.7 0.0 0.41 9.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2478) 2-Hacid_dh_C PF02826.14 KKK25088.1 - 1e-56 190.9 0.0 1.4e-56 190.4 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KKK25088.1 - 5.3e-14 51.8 0.0 6.5e-14 51.5 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 KKK25088.1 - 7e-05 22.7 0.1 0.00013 21.8 0.1 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.7 KKK25088.1 - 0.025 13.9 0.0 0.043 13.1 0.0 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain F420_oxidored PF03807.12 KKK25088.1 - 0.07 13.5 0.0 0.17 12.3 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Peptidase_S8 PF00082.17 KKK25089.1 - 2.5e-44 151.5 15.7 3.7e-44 150.9 10.9 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 KKK25089.1 - 1.5e-16 60.6 0.2 2.9e-16 59.7 0.1 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 NfeD PF01957.13 KKK25090.1 - 0.13 12.3 0.8 0.22 11.6 0.3 1.6 1 1 0 1 1 1 0 NfeD-like C-terminal, partner-binding TauE PF01925.14 KKK25090.1 - 0.55 9.6 6.9 0.041 13.3 1.5 1.5 2 0 0 2 2 2 0 Sulfite exporter TauE/SafE GST_N_3 PF13417.1 KKK25092.1 - 2.2e-24 85.4 0.1 4.1e-24 84.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KKK25092.1 - 4.5e-16 58.6 0.0 9.2e-16 57.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KKK25092.1 - 2e-06 27.5 1.4 3.3e-06 26.9 0.4 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 KKK25092.1 - 1.4e-05 25.1 0.0 2.6e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Cas_Cas02710 PF09670.5 KKK25092.1 - 0.021 13.4 0.0 0.034 12.7 0.0 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Cas02710) Glutaredoxin PF00462.19 KKK25092.1 - 0.026 14.4 0.0 0.059 13.3 0.0 1.6 1 0 0 1 1 1 0 Glutaredoxin GST_C_3 PF14497.1 KKK25092.1 - 0.062 13.7 0.0 0.18 12.2 0.0 1.8 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain MFS_1 PF07690.11 KKK25093.1 - 1.5e-17 63.3 36.4 1.2e-16 60.4 20.6 3.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KKK25093.1 - 8.6e-11 41.0 8.0 8.6e-11 41.0 5.5 2.1 2 1 0 2 2 2 1 Sugar (and other) transporter YL1 PF05764.8 KKK25095.1 - 0.0095 15.5 1.0 0.016 14.7 0.6 1.4 1 1 0 1 1 1 1 YL1 nuclear protein SUZ PF12752.2 KKK25095.1 - 0.048 14.1 15.9 0.045 14.2 6.5 3.5 2 1 0 2 2 2 0 SUZ domain DEAD PF00270.24 KKK25105.1 - 9.1e-36 122.8 0.0 1.6e-35 122.1 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KKK25105.1 - 6.5e-24 83.5 0.0 4.7e-23 80.8 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KKK25105.1 - 3.8e-06 26.8 0.0 1e-05 25.4 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 KKK25105.1 - 0.012 14.7 0.0 0.059 12.4 0.0 2.0 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit Wbp11 PF09429.5 KKK25106.1 - 1.7e-22 79.1 14.0 1.7e-22 79.1 9.7 2.7 3 1 1 4 4 4 1 WW domain binding protein 11 DUF3038 PF11237.3 KKK25106.1 - 0.014 15.2 2.2 0.024 14.4 1.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3038) DUF4332 PF14229.1 KKK25106.1 - 0.15 12.0 2.5 0.21 11.5 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4332) Baculo_PEP_C PF04513.7 KKK25107.1 - 0.037 13.8 2.5 1.3 8.8 0.9 2.1 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.7 KKK25107.1 - 0.055 13.7 2.2 2.5 8.4 1.5 2.5 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Nbl1_Borealin_N PF10444.4 KKK25107.1 - 0.078 12.3 0.9 0.078 12.3 0.6 2.3 2 1 0 2 2 2 0 Nbl1 / Borealin N terminal Glyco_hydro_3_C PF01915.17 KKK25107.1 - 0.088 12.3 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 3 C-terminal domain NAP PF00956.13 KKK25107.1 - 0.15 11.1 0.1 0.18 10.8 0.1 1.2 1 0 0 1 1 1 0 Nucleosome assembly protein (NAP) Adeno_PIX PF03955.9 KKK25107.1 - 0.16 12.5 1.2 15 6.1 0.3 2.2 1 1 1 2 2 2 0 Adenovirus hexon-associated protein (IX) Fzo_mitofusin PF04799.8 KKK25107.1 - 0.19 11.1 1.2 0.74 9.1 0.8 1.8 1 1 0 1 1 1 0 fzo-like conserved region ING PF12998.2 KKK25107.1 - 0.27 11.5 3.5 4.3 7.6 0.0 2.2 1 1 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding Syntaxin PF00804.20 KKK25107.1 - 0.31 11.2 6.1 0.25 11.5 0.6 2.4 2 1 1 3 3 2 0 Syntaxin HSCB_C PF07743.8 KKK25107.1 - 0.33 11.4 2.9 2.4 8.6 0.5 2.3 1 1 0 2 2 2 0 HSCB C-terminal oligomerisation domain CorA PF01544.13 KKK25107.1 - 0.49 9.3 5.5 0.97 8.4 2.1 1.9 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein IncA PF04156.9 KKK25107.1 - 0.8 9.2 6.1 1.1 8.8 4.2 1.4 1 1 0 1 1 1 0 IncA protein Uds1 PF15456.1 KKK25107.1 - 0.9 9.5 4.9 1.1 9.2 1.9 2.1 2 1 0 2 2 2 0 Up-regulated During Septation GreA_GreB_N PF03449.10 KKK25107.1 - 1.3 9.1 4.8 1.9 8.5 0.3 2.9 2 1 1 3 3 3 0 Transcription elongation factor, N-terminal Matrilin_ccoil PF10393.4 KKK25107.1 - 1.6 8.1 5.8 4.8 6.6 0.4 3.0 3 0 0 3 3 3 0 Trimeric coiled-coil oligomerisation domain of matrilin ORF11CD3 PF10549.4 KKK25107.1 - 1.6 8.5 10.0 0.54 10.0 0.5 3.3 3 0 0 3 3 3 0 ORF11CD3 domain DUF4164 PF13747.1 KKK25107.1 - 9.6 6.4 8.5 4.9 7.3 0.5 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) Rpr2 PF04032.11 KKK25108.1 - 1.2e-28 98.7 0.3 3.1e-28 97.4 0.2 1.7 1 1 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain IBR PF01485.16 KKK25108.1 - 0.093 12.6 0.8 0.21 11.5 0.5 1.6 1 0 0 1 1 1 0 IBR domain DZR PF12773.2 KKK25108.1 - 0.2 11.4 5.1 1.6 8.6 3.6 2.3 1 1 0 1 1 1 0 Double zinc ribbon Pkinase PF00069.20 KKK25109.1 - 2.1e-58 197.5 0.3 4e-58 196.5 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK25109.1 - 1e-36 126.3 0.0 2.9e-25 88.8 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KKK25109.1 - 0.01 14.8 0.0 0.022 13.7 0.0 1.5 1 0 0 1 1 1 0 Kinase-like APH PF01636.18 KKK25109.1 - 0.037 13.7 1.4 0.11 12.2 0.0 2.4 2 1 0 2 2 2 0 Phosphotransferase enzyme family DUF607 PF04678.8 KKK25109.1 - 0.069 13.0 1.3 0.13 12.1 0.9 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF607 Effector_1 PF04518.7 KKK25109.1 - 0.11 11.4 1.1 0.18 10.7 0.7 1.2 1 0 0 1 1 1 0 Effector from type III secretion system DUF677 PF05055.7 KKK25109.1 - 0.15 10.6 8.5 0.24 10.0 5.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF677) APG6 PF04111.7 KKK25109.1 - 5.6 5.9 9.7 9.7 5.1 6.7 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 BTB PF00651.26 KKK25110.1 - 3.1e-26 91.5 0.0 1.7e-14 53.7 0.0 2.6 2 0 0 2 2 2 2 BTB/POZ domain Ank_4 PF13637.1 KKK25110.1 - 0.014 15.8 0.0 0.087 13.3 0.0 2.3 3 0 0 3 3 3 0 Ankyrin repeats (many copies) Ank_2 PF12796.2 KKK25110.1 - 0.037 14.3 0.0 0.1 12.9 0.0 1.7 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Glyco_hydro_35 PF01301.14 KKK25120.1 - 2.9e-69 233.8 6.5 4.1e-69 233.3 4.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom2 PF10435.4 KKK25120.1 - 5.9e-57 191.9 3.1 5.9e-57 191.9 2.1 1.7 2 0 0 2 2 2 1 Beta-galactosidase, domain 2 BetaGal_dom4_5 PF13364.1 KKK25120.1 - 2.2e-49 166.3 1.8 2.2e-24 85.8 0.8 2.8 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain BetaGal_dom3 PF13363.1 KKK25120.1 - 3.1e-26 90.5 0.1 7.5e-26 89.3 0.1 1.7 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 Y_phosphatase3 PF13350.1 KKK25120.1 - 3.4e-23 82.7 0.0 7.8e-23 81.5 0.0 1.7 1 0 0 1 1 1 1 Tyrosine phosphatase family Glyco_hydro_42 PF02449.10 KKK25120.1 - 7.9e-05 21.9 0.1 0.00091 18.4 0.1 2.2 1 1 1 2 2 2 1 Beta-galactosidase Y_phosphatase2 PF03162.8 KKK25120.1 - 0.0055 16.0 0.0 0.019 14.3 0.0 1.8 2 0 0 2 2 2 1 Tyrosine phosphatase family Y_phosphatase PF00102.22 KKK25120.1 - 0.015 14.6 0.0 0.029 13.6 0.0 1.4 1 0 0 1 1 1 0 Protein-tyrosine phosphatase DSPc PF00782.15 KKK25120.1 - 0.067 12.7 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain DUF3812 PF12757.2 KKK25121.1 - 2.2e-33 114.9 10.6 2.2e-33 114.9 7.3 3.3 3 0 0 3 3 3 1 Protein of unknown function (DUF3812) Pkinase PF00069.20 KKK25123.1 - 1.1e-68 231.2 0.0 1.9e-68 230.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK25123.1 - 8.3e-42 143.0 0.0 1.2e-41 142.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KKK25123.1 - 9.1e-11 41.2 0.0 3.6e-09 36.0 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 KKK25123.1 - 0.041 12.9 0.3 0.1 11.6 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KKK25123.1 - 0.073 12.7 4.8 1.8 8.2 0.1 3.1 2 1 1 3 3 3 0 Phosphotransferase enzyme family Pkinase PF00069.20 KKK25124.1 - 5.6e-35 120.7 0.0 8.8e-35 120.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Rtt106 PF08512.7 KKK25124.1 - 4.1e-27 94.0 0.1 1.3e-26 92.3 0.1 1.9 2 0 0 2 2 2 1 Histone chaperone Rttp106-like Pkinase_Tyr PF07714.12 KKK25124.1 - 9.7e-14 51.0 0.0 1.5e-13 50.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase CDC45 PF02724.9 KKK25124.1 - 0.11 10.5 10.9 0.16 9.9 7.6 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF1379 PF07126.7 KKK25124.1 - 0.17 11.2 0.9 1.9 7.8 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1379) Daxx PF03344.10 KKK25124.1 - 0.7 8.2 19.6 1.3 7.4 13.6 1.3 1 0 0 1 1 1 0 Daxx Family Vfa1 PF08432.5 KKK25124.1 - 3.5 7.6 10.0 8.2 6.4 6.9 1.6 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 BUD22 PF09073.5 KKK25124.1 - 4 6.3 22.6 7.3 5.5 15.7 1.3 1 0 0 1 1 1 0 BUD22 Prenyltrans PF00432.16 KKK25125.1 - 6.2e-33 112.0 10.7 1.6e-10 40.3 0.0 6.5 6 1 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 KKK25125.1 - 3.9e-26 91.6 0.0 4.6e-18 65.6 0.0 3.3 2 1 1 3 3 3 3 Prenyltransferase-like Prenyltrans_1 PF13243.1 KKK25125.1 - 0.00038 20.4 0.0 0.027 14.4 0.0 3.4 2 1 2 4 4 4 2 Prenyltransferase-like DnaJ PF00226.26 KKK25126.1 - 6.6e-12 44.9 1.9 2.2e-11 43.2 1.3 1.9 1 1 0 1 1 1 1 DnaJ domain Frag1 PF10277.4 KKK25127.1 - 5.7e-43 146.8 16.4 6.6e-43 146.6 11.4 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family SUR7 PF06687.7 KKK25127.1 - 0.022 14.3 1.0 0.022 14.3 0.7 3.1 1 1 1 2 2 2 0 SUR7/PalI family DUF3671 PF12420.3 KKK25127.1 - 1.6 8.7 11.7 0.086 12.8 0.7 2.7 3 0 0 3 3 3 0 Protein of unknown function PRA1 PF03208.14 KKK25128.1 - 3.2e-42 143.4 1.2 3.8e-42 143.2 0.8 1.0 1 0 0 1 1 1 1 PRA1 family protein TraS PF10624.4 KKK25128.1 - 1.7 8.1 4.9 0.69 9.4 0.9 1.9 1 1 1 2 2 2 0 Plasmid conjugative transfer entry exclusion protein TraS CFEM PF05730.6 KKK25130.1 - 3.8e-14 52.2 15.5 3.8e-14 52.2 10.8 2.3 2 1 0 2 2 2 1 CFEM domain Menin PF05053.8 KKK25130.1 - 0.86 7.6 5.1 1.1 7.3 3.5 1.2 1 0 0 1 1 1 0 Menin DNA_pol_viral_N PF00242.12 KKK25130.1 - 1.1 8.2 7.9 1.1 8.1 5.5 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain DUF2413 PF10310.4 KKK25130.1 - 1.3 7.7 9.7 1.7 7.3 6.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) TFIIA PF03153.8 KKK25130.1 - 2.6 7.8 7.3 3.1 7.6 5.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Macoilin PF09726.4 KKK25130.1 - 3 5.9 11.7 3.6 5.7 8.1 1.0 1 0 0 1 1 1 0 Transmembrane protein Tmemb_cc2 PF10267.4 KKK25130.1 - 3.2 6.2 7.3 3.7 6.0 5.1 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Pneumo_att_G PF05539.6 KKK25130.1 - 7.1 5.8 33.5 8.9 5.5 23.3 1.0 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G Ilm1 PF10311.4 KKK25131.1 - 5.1e-68 227.7 1.5 6.7e-68 227.3 1.0 1.1 1 0 0 1 1 1 1 Increased loss of mitochondrial DNA protein 1 MFS_1 PF07690.11 KKK25132.1 - 3.9e-34 117.9 19.3 3.9e-34 117.9 13.4 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KKK25132.1 - 7e-10 38.0 7.0 7e-10 38.0 4.9 3.1 2 1 1 3 3 3 1 Sugar (and other) transporter NAD_kinase PF01513.16 KKK25169.1 - 1e-64 218.0 0.0 1.5e-64 217.5 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase DUF2848 PF11010.3 KKK25169.1 - 0.017 14.5 0.1 0.027 13.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2848) DUF1583 PF07622.6 KKK25169.1 - 0.048 12.1 0.0 0.07 11.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1583) TRAPP PF04051.11 KKK25170.1 - 1.4e-36 125.3 0.0 1.8e-36 124.9 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component GTP_EFTU PF00009.22 KKK25179.1 - 2.3e-05 23.9 0.0 2.4e-05 23.8 0.0 1.0 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain NAD_binding_2 PF03446.10 KKK25188.1 - 2.1e-34 118.7 0.1 3.2e-34 118.1 0.1 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 KKK25188.1 - 6.2e-33 113.4 0.0 1.1e-32 112.6 0.0 1.5 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.12 KKK25188.1 - 2e-06 28.1 0.0 5.1e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent OCD_Mu_crystall PF02423.10 KKK25188.1 - 0.00067 18.5 0.0 0.0015 17.3 0.0 1.6 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family TGS PF02824.16 KKK25188.1 - 0.046 13.5 0.1 0.25 11.1 0.0 2.2 2 0 0 2 2 2 0 TGS domain 2-Hacid_dh_C PF02826.14 KKK25188.1 - 0.071 12.2 0.1 0.3 10.2 0.0 1.9 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain MOR2-PAG1_N PF14222.1 KKK25189.1 - 2.2e-225 749.5 0.0 3.6e-225 748.8 0.0 1.4 1 0 0 1 1 1 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.1 KKK25189.1 - 9.7e-96 320.5 0.0 2.4e-95 319.2 0.0 1.7 1 0 0 1 1 1 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.1 KKK25189.1 - 2.9e-37 127.8 13.3 3e-13 48.3 0.4 3.9 2 1 1 3 3 3 3 Cell morphogenesis central region MARVEL PF01284.18 KKK25190.1 - 0.0056 16.5 18.3 0.017 14.9 12.9 1.6 1 1 0 1 1 1 1 Membrane-associating domain RCR PF12273.3 KKK25190.1 - 0.0078 16.7 1.8 0.013 16.0 0.1 2.0 2 0 0 2 2 2 1 Chitin synthesis regulation, resistance to Congo red SUR7 PF06687.7 KKK25190.1 - 0.21 11.1 3.8 4.3 6.8 0.4 2.1 1 1 1 2 2 2 0 SUR7/PalI family Pex14_N PF04695.8 KKK25191.1 - 0.53 10.3 8.3 1.3 9.0 5.8 1.7 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Sporozoite_P67 PF05642.6 KKK25191.1 - 6.3 4.5 15.4 7.8 4.2 10.7 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen UvdE PF03851.9 KKK25192.1 - 6.6e-111 369.7 0.0 8.3e-111 369.4 0.0 1.1 1 0 0 1 1 1 1 UV-endonuclease UvdE DUF2183 PF09949.4 KKK25193.1 - 1.3e-32 111.7 0.0 2.7e-32 110.6 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) CarboxypepD_reg PF13620.1 KKK25193.1 - 0.021 14.8 0.0 0.072 13.1 0.0 1.9 2 0 0 2 2 2 0 Carboxypeptidase regulatory-like domain FAD_binding_1 PF00667.15 KKK25194.1 - 9e-62 208.3 0.0 1.4e-61 207.7 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 KKK25194.1 - 1.4e-33 115.9 2.5 2.9e-33 114.8 1.8 1.6 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 KKK25194.1 - 1.6e-22 80.1 0.0 1.4e-21 77.1 0.0 2.2 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.2 KKK25194.1 - 0.0077 16.2 0.0 0.029 14.3 0.0 2.0 2 0 0 2 2 2 1 Flavodoxin domain MMS1_N PF10433.4 KKK25195.1 - 6.5e-92 308.2 0.0 8.9e-92 307.8 0.0 1.1 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.10 KKK25195.1 - 2.6e-75 253.4 0.0 6.1e-72 242.4 0.0 3.9 4 0 0 4 4 4 2 CPSF A subunit region PGA2 PF07543.7 KKK25196.1 - 1e-46 158.2 4.4 1.3e-46 157.9 3.1 1.1 1 0 0 1 1 1 1 Protein trafficking PGA2 EST1 PF10374.4 KKK25196.1 - 0.0031 17.5 0.5 0.0046 16.9 0.0 1.4 2 0 0 2 2 2 1 Telomerase activating protein Est1 Folate_carrier PF01770.13 KKK25196.1 - 0.012 14.1 0.0 0.018 13.5 0.0 1.2 1 0 0 1 1 1 0 Reduced folate carrier BLVR PF06375.6 KKK25196.1 - 0.67 9.7 11.8 0.05 13.4 0.8 2.1 1 1 1 2 2 2 0 Bovine leukaemia virus receptor (BLVR) CENP-S PF15630.1 KKK25197.1 - 2.9e-34 117.0 0.0 3.6e-34 116.7 0.0 1.1 1 0 0 1 1 1 1 Kinetochore component CENP-S CENP-T PF15511.1 KKK25197.1 - 4.5e-06 26.1 0.0 5.8e-06 25.8 0.0 1.1 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T Bromo_TP PF07524.8 KKK25197.1 - 0.011 15.4 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated TAF PF02969.12 KKK25197.1 - 0.093 12.6 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) CPSase_L_D2 PF02786.12 KKK25198.1 - 6.7e-114 378.4 0.1 6.1e-84 280.5 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.17 KKK25198.1 - 4.4e-46 155.6 0.0 1.3e-45 154.1 0.0 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.23 KKK25198.1 - 7.5e-44 149.4 0.0 4.5e-43 146.9 0.0 2.2 2 0 0 2 2 2 1 Glutamine amidotransferase class-I OTCace_N PF02729.16 KKK25198.1 - 5.7e-43 145.9 0.0 1.1e-42 145.0 0.0 1.5 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_L_D3 PF02787.14 KKK25198.1 - 4.1e-40 136.3 0.0 1e-39 135.1 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain CPSase_L_chain PF00289.17 KKK25198.1 - 7.7e-40 135.4 0.0 5.1e-19 68.3 0.0 3.1 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain OTCace PF00185.19 KKK25198.1 - 7e-36 123.4 0.0 1.7e-35 122.2 0.0 1.7 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain ATP-grasp_4 PF13535.1 KKK25198.1 - 2.8e-35 121.7 0.1 1.3e-20 73.8 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain MGS PF02142.17 KKK25198.1 - 6.8e-22 77.2 0.0 4.4e-21 74.6 0.0 2.6 2 0 0 2 2 1 1 MGS-like domain ATPgrasp_Ter PF15632.1 KKK25198.1 - 4e-20 71.8 0.0 7.5e-09 34.7 0.0 4.3 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 KKK25198.1 - 1.1e-16 60.7 0.3 1.3e-07 31.2 0.0 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 KKK25198.1 - 9.9e-16 57.5 0.1 5.5e-07 29.0 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain Peptidase_C26 PF07722.8 KKK25198.1 - 1.9e-06 27.5 0.2 6.2e-05 22.5 0.1 2.6 1 1 0 1 1 1 1 Peptidase C26 ATP-grasp_3 PF02655.9 KKK25198.1 - 5.9e-06 26.2 0.4 0.16 11.8 0.0 2.8 2 0 0 2 2 2 2 ATP-grasp domain GARS_A PF01071.14 KKK25198.1 - 0.0029 17.2 0.3 0.38 10.2 0.0 2.7 3 0 0 3 3 3 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Synaptobrevin PF00957.16 KKK25199.1 - 9.5e-32 108.4 0.0 1.3e-31 108.0 0.0 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 KKK25199.1 - 1e-24 85.8 0.0 1.5e-24 85.3 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain DUF879 PF05947.7 KKK25199.1 - 0.06 11.7 0.0 0.08 11.2 0.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF879) DUF2628 PF10947.3 KKK25199.1 - 0.14 12.0 1.3 0.26 11.0 0.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2628) Pkinase PF00069.20 KKK25201.1 - 4.6e-24 84.9 0.0 7.1e-24 84.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain HEAT PF02985.17 KKK25201.1 - 1.6e-12 46.3 7.3 0.0031 17.4 0.1 6.9 6 0 0 6 6 6 3 HEAT repeat WD40 PF00400.27 KKK25201.1 - 1.8e-12 46.6 13.9 1.7e-08 34.0 0.1 4.6 5 0 0 5 5 5 2 WD domain, G-beta repeat HEAT_2 PF13646.1 KKK25201.1 - 4.4e-09 36.5 2.8 0.036 14.3 0.0 4.7 3 1 1 4 4 4 3 HEAT repeats Pkinase_Tyr PF07714.12 KKK25201.1 - 0.00011 21.3 0.0 0.00018 20.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT_EZ PF13513.1 KKK25201.1 - 0.00058 20.2 4.4 0.012 16.1 0.4 4.3 5 0 0 5 5 5 1 HEAT-like repeat DUF2454 PF10521.4 KKK25201.1 - 0.0016 17.5 0.1 0.0048 15.9 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF2454) DUF2435 PF10363.4 KKK25201.1 - 0.047 13.5 0.2 4.1 7.3 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2435) Adaptin_N PF01602.15 KKK25201.1 - 0.072 11.4 2.2 2.6 6.2 0.1 2.2 2 0 0 2 2 2 0 Adaptin N terminal region adh_short PF00106.20 KKK25204.1 - 8.9e-31 107.0 0.7 1.4e-30 106.4 0.5 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KKK25204.1 - 1.1e-25 90.7 0.2 1.3e-25 90.5 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KKK25204.1 - 4.5e-13 49.2 0.4 1e-12 48.0 0.3 1.6 1 1 0 1 1 1 1 KR domain DUF3087 PF11286.3 KKK25204.1 - 0.02 14.1 0.0 4.7 6.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3087) DENN PF02141.16 KKK25205.1 - 2.7e-40 138.0 0.1 4.5e-40 137.3 0.0 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.13 KKK25205.1 - 0.0019 18.0 0.0 0.0077 16.1 0.0 2.1 1 0 0 1 1 1 1 uDENN domain Elongin_A PF06881.6 KKK25205.1 - 0.015 15.6 5.8 0.015 15.6 4.0 2.5 2 1 1 3 3 3 0 RNA polymerase II transcription factor SIII (Elongin) subunit A ADIP PF11559.3 KKK25205.1 - 7.9 6.3 21.8 2.4 8.0 4.7 2.4 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF2570 PF10828.3 KKK25205.1 - 8.2 6.0 11.0 3.8 7.1 5.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2570) Fungal_trans PF04082.13 KKK25206.1 - 6.1e-10 38.4 0.0 1e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK25206.1 - 8.8e-10 38.3 4.0 1.6e-09 37.5 2.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ion_trans PF00520.26 KKK25207.1 - 0.00011 21.4 7.3 0.00011 21.4 5.1 2.0 1 1 0 2 2 2 1 Ion transport protein RabGAP-TBC PF00566.13 KKK25208.1 - 4.7e-41 140.6 0.0 1.6e-39 135.6 0.0 2.8 3 0 0 3 3 3 1 Rab-GTPase-TBC domain Nucleoplasmin PF03066.10 KKK25208.1 - 1.1 8.7 11.1 3.1 7.2 7.7 1.7 1 0 0 1 1 1 0 Nucleoplasmin NOA36 PF06524.7 KKK25208.1 - 1.2 8.3 6.4 2.3 7.3 4.5 1.4 1 0 0 1 1 1 0 NOA36 protein CENP-B_dimeris PF09026.5 KKK25208.1 - 3.6 7.8 13.6 9.8 6.4 9.4 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Sigma70_ner PF04546.8 KKK25208.1 - 3.8 7.0 7.5 8.7 5.9 5.2 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region RXT2_N PF08595.6 KKK25208.1 - 5.1 6.8 7.2 17 5.1 5.0 1.9 1 0 0 1 1 1 0 RXT2-like, N-terminal AMP-binding PF00501.23 KKK25209.1 - 1.4e-226 751.6 0.0 2.7e-79 266.5 0.0 3.3 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.15 KKK25209.1 - 5.5e-154 511.4 0.0 2.9e-35 121.5 0.0 5.3 5 0 0 5 5 5 5 Condensation domain PP-binding PF00550.20 KKK25209.1 - 2.7e-44 149.2 3.5 7.1e-11 42.2 0.0 6.0 5 0 0 5 5 5 5 Phosphopantetheine attachment site AMP-binding_C PF13193.1 KKK25209.1 - 7.6e-20 71.6 3.0 1.2e-08 35.7 0.2 4.0 3 0 0 3 3 3 3 AMP-binding enzyme C-terminal domain AATase PF07247.7 KKK25209.1 - 0.0028 16.2 0.1 0.061 11.8 0.0 3.0 4 0 0 4 4 4 1 Alcohol acetyltransferase WEMBL PF05701.6 KKK25209.1 - 7.3 4.9 3.1 12 4.2 2.1 1.2 1 0 0 1 1 1 0 Weak chloroplast movement under blue light Ion_trans PF00520.26 KKK25211.1 - 2.3e-05 23.7 23.3 2.3e-05 23.7 16.1 1.7 1 1 0 1 1 1 1 Ion transport protein GGGtGRT PF14057.1 KKK25211.1 - 0.16 10.7 0.0 0.24 10.1 0.0 1.1 1 0 0 1 1 1 0 GGGtGRT protein Casein_kappa PF00997.13 KKK25211.1 - 0.19 11.4 0.7 19 4.9 0.0 2.4 2 0 0 2 2 2 0 Kappa casein NOA36 PF06524.7 KKK25211.1 - 2.8 7.0 5.4 7.1 5.7 3.7 1.6 1 0 0 1 1 1 0 NOA36 protein NUDIX PF00293.23 KKK25212.1 - 4.6e-28 97.5 0.0 7.1e-28 96.9 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain zf-C2H2_4 PF13894.1 KKK25213.1 - 2.4e-12 46.2 11.4 6.4e-05 23.0 0.0 3.9 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.21 KKK25213.1 - 9e-11 41.4 14.1 0.00048 20.3 0.1 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-met PF12874.2 KKK25213.1 - 9.1e-06 25.6 0.3 0.19 11.9 0.2 2.8 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.1 KKK25213.1 - 1.4e-05 25.1 11.6 0.05 13.9 2.4 3.5 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.3 KKK25213.1 - 0.0028 17.7 2.2 2.8 8.1 0.0 3.0 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 KKK25213.1 - 0.087 12.9 3.9 0.38 10.8 0.5 2.7 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-met2 PF12907.2 KKK25213.1 - 1.3 9.0 6.2 9.6 6.2 0.0 2.7 2 1 1 3 3 3 0 Zinc-binding zf-BED PF02892.10 KKK25213.1 - 4.2 7.2 8.0 36 4.2 4.0 2.9 1 1 2 3 3 3 0 BED zinc finger MatE PF01554.13 KKK25214.1 - 1.2e-55 187.5 29.4 1.5e-31 109.2 5.1 2.7 3 0 0 3 3 3 2 MatE Polysacc_synt_C PF14667.1 KKK25214.1 - 0.00026 20.8 4.1 0.00026 20.8 2.8 4.1 4 1 0 4 4 4 2 Polysaccharide biosynthesis C-terminal domain DUF202 PF02656.10 KKK25215.1 - 6.9e-21 74.2 0.4 6.9e-21 74.2 0.3 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF2976 PF11190.3 KKK25215.1 - 0.02 14.4 1.3 0.049 13.1 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2976) COX4_pro_2 PF07835.7 KKK25215.1 - 0.041 13.8 0.0 0.11 12.5 0.0 1.7 1 0 0 1 1 1 0 Bacterial aa3 type cytochrome c oxidase subunit IV GWT1 PF06423.7 KKK25215.1 - 0.063 13.3 0.7 0.087 12.9 0.5 1.2 1 0 0 1 1 1 0 GWT1 Lysis_col PF02402.11 KKK25215.1 - 0.19 11.3 0.9 1.1 8.9 0.0 2.2 2 0 0 2 2 2 0 Lysis protein Yip1 PF04893.12 KKK25215.1 - 0.26 10.7 6.3 0.19 11.2 2.7 1.8 1 1 1 2 2 2 0 Yip1 domain Ost4 PF10215.4 KKK25215.1 - 9.9 5.7 9.3 0.48 9.9 0.5 2.7 3 0 0 3 3 3 0 Oligosaccaryltransferase DEAD PF00270.24 KKK25216.1 - 6.8e-45 152.5 0.2 3.7e-44 150.2 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase DBP10CT PF08147.7 KKK25216.1 - 2.2e-21 75.4 1.3 9.3e-21 73.4 0.9 2.2 1 0 0 1 1 1 1 DBP10CT (NUC160) domain Helicase_C PF00271.26 KKK25216.1 - 3.9e-21 74.7 0.2 1.8e-20 72.5 0.1 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RPA_C PF08784.6 KKK25217.1 - 1.2e-15 57.7 0.3 5.2e-15 55.7 0.0 2.2 3 0 0 3 3 3 1 Replication protein A C terminal HTH_24 PF13412.1 KKK25217.1 - 0.0044 16.3 0.0 0.0092 15.3 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding tRNA_anti-codon PF01336.20 KKK25217.1 - 0.0055 16.5 0.1 0.017 14.9 0.0 1.7 2 1 0 2 2 2 1 OB-fold nucleic acid binding domain DEAD PF00270.24 KKK25218.1 - 5.3e-45 152.9 0.1 1.8e-44 151.2 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF4217 PF13959.1 KKK25218.1 - 5.6e-25 86.6 0.1 1.2e-24 85.5 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 KKK25218.1 - 1.1e-21 76.4 0.0 3.1e-21 75.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 KKK25218.1 - 0.001 17.9 0.0 0.0027 16.5 0.0 1.7 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF4538 PF15061.1 KKK25219.1 - 0.086 12.1 5.4 0.19 11.0 2.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4538) RRM_1 PF00076.17 KKK25220.1 - 1.4e-22 79.1 0.2 9e-11 41.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KKK25220.1 - 1.8e-15 56.6 0.0 7.2e-08 32.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KKK25220.1 - 0.032 14.0 1.5 2.2 8.1 0.1 3.0 2 1 1 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PAPS_reduct PF01507.14 KKK25221.1 - 2.4e-26 92.6 0.0 2.5e-24 86.0 0.0 2.8 2 1 0 2 2 2 1 Phosphoadenosine phosphosulfate reductase family DnaJ PF00226.26 KKK25221.1 - 2.5e-14 52.7 1.7 6.4e-14 51.4 0.5 2.3 3 0 0 3 3 3 1 DnaJ domain TPR_11 PF13414.1 KKK25224.1 - 1.1e-10 40.9 0.2 2.7e-05 23.7 0.0 3.6 2 1 2 4 4 4 2 TPR repeat TPR_1 PF00515.23 KKK25224.1 - 3.7e-06 26.3 0.0 0.00026 20.4 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 KKK25224.1 - 8.4e-06 25.5 0.1 0.00035 20.5 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 KKK25224.1 - 1.4e-05 25.3 0.0 3.6e-05 24.0 0.0 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.1 KKK25224.1 - 2.3e-05 24.9 0.1 0.45 11.2 0.0 2.9 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 KKK25224.1 - 3.6e-05 24.0 1.9 0.012 16.1 0.1 3.9 3 2 1 4 4 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 KKK25224.1 - 3.8e-05 23.2 0.2 0.0017 18.1 0.0 3.7 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.1 KKK25224.1 - 0.0006 19.4 0.0 0.015 15.0 0.0 3.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 KKK25224.1 - 0.00063 19.6 0.1 0.087 12.7 0.0 2.8 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_20 PF14561.1 KKK25224.1 - 0.0087 16.1 0.0 0.025 14.6 0.0 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.1 KKK25224.1 - 0.032 14.0 0.0 0.99 9.3 0.0 3.2 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.1 KKK25224.1 - 0.073 12.9 2.3 0.34 10.7 0.1 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat HrpJ PF07201.6 KKK25224.1 - 0.092 12.7 0.2 0.48 10.4 0.0 2.2 3 0 0 3 3 3 0 HrpJ-like domain KorB PF08535.5 KKK25224.1 - 0.12 12.5 0.0 0.27 11.4 0.0 1.6 1 0 0 1 1 1 0 KorB domain Sigma70_r4 PF04545.11 KKK25224.1 - 0.4 10.0 4.8 7 6.0 1.8 2.5 2 0 0 2 2 2 0 Sigma-70, region 4 Adaptin_N PF01602.15 KKK25225.1 - 3.7e-49 167.4 0.0 1e-48 165.9 0.0 1.7 1 1 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 KKK25225.1 - 1.4e-06 28.5 1.4 0.14 12.4 0.1 3.7 3 0 0 3 3 3 2 HEAT repeats HEAT_EZ PF13513.1 KKK25225.1 - 0.0012 19.3 5.6 0.29 11.6 0.0 4.8 4 2 2 6 6 6 2 HEAT-like repeat Cnd1 PF12717.2 KKK25225.1 - 0.003 17.4 2.8 0.16 11.7 0.4 2.5 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 Cnd3 PF12719.2 KKK25225.1 - 0.011 14.7 0.1 0.063 12.2 0.0 2.2 2 0 0 2 2 2 0 Nuclear condensing complex subunits, C-term domain HEAT PF02985.17 KKK25225.1 - 0.036 14.1 4.7 5.5 7.3 0.1 4.2 4 0 0 4 4 4 0 HEAT repeat RAMP4 PF06624.7 KKK25226.1 - 0.00025 20.5 2.3 0.00054 19.4 1.6 1.6 1 1 0 1 1 1 1 Ribosome associated membrane protein RAMP4 Neur_chan_memb PF02932.11 KKK25226.1 - 0.067 13.0 0.0 0.088 12.6 0.0 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region APH PF01636.18 KKK25227.1 - 2.2e-11 43.9 0.0 1.3e-10 41.3 0.0 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KKK25227.1 - 0.0013 18.3 0.0 0.0018 17.8 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Collagen_bind_2 PF12904.2 KKK25227.1 - 0.026 14.2 0.1 2.7 7.8 0.0 2.4 1 1 1 2 2 2 0 Putative collagen-binding domain of a collagenase Pkinase PF00069.20 KKK25227.1 - 0.14 11.2 0.0 0.51 9.4 0.0 1.7 1 1 1 2 2 2 0 Protein kinase domain Utp21 PF04192.7 KKK25228.1 - 4.8e-77 258.2 0.0 7.2e-77 257.6 0.0 1.3 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.27 KKK25228.1 - 6.7e-24 82.8 27.6 3.3e-05 23.5 0.0 10.3 12 0 0 12 12 12 6 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 KKK25228.1 - 0.015 13.5 0.1 0.1 10.8 0.0 2.1 2 0 0 2 2 2 0 Cytochrome D1 heme domain XPG_I_2 PF12813.2 KKK25229.1 - 8.1e-76 254.7 0.0 1.1e-75 254.2 0.0 1.2 1 0 0 1 1 1 1 XPG domain containing XPG_I PF00867.13 KKK25229.1 - 0.074 13.1 0.0 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 XPG I-region Abhydrolase_6 PF12697.2 KKK25231.1 - 3.9e-13 49.7 1.3 8.4e-13 48.7 0.8 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KKK25231.1 - 7.7e-13 48.4 0.0 2.9e-12 46.5 0.0 2.0 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 KKK25231.1 - 4e-05 23.3 0.0 6.1e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.15 KKK25231.1 - 0.00074 19.1 0.0 0.0016 18.0 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 KKK25231.1 - 0.012 15.4 0.1 0.11 12.3 0.1 2.2 1 1 0 1 1 1 0 Putative lysophospholipase Peptidase_S9 PF00326.16 KKK25231.1 - 0.034 13.3 0.0 2.7 7.1 0.0 2.3 2 0 0 2 2 2 0 Prolyl oligopeptidase family Cutinase PF01083.17 KKK25231.1 - 0.15 11.8 0.0 0.31 10.7 0.0 1.6 2 0 0 2 2 2 0 Cutinase TLD PF07534.11 KKK25233.1 - 0.0018 18.2 0.0 0.003 17.5 0.0 1.3 1 0 0 1 1 1 1 TLD DUF2368 PF10166.4 KKK25233.1 - 0.029 13.9 0.0 0.057 13.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2368) NMT PF01233.14 KKK25234.1 - 1.4e-78 262.1 0.1 3.1e-78 261.0 0.0 1.6 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain NMT_C PF02799.10 KKK25234.1 - 4.9e-73 244.5 0.2 1.6e-51 174.4 0.1 2.4 1 1 1 2 2 2 2 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain Acetyltransf_9 PF13527.1 KKK25234.1 - 8e-07 28.9 0.0 2.1e-05 24.3 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 KKK25234.1 - 0.0032 17.6 0.1 0.009 16.1 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain CP_ATPgrasp_2 PF14403.1 KKK25234.1 - 0.0036 16.0 0.5 0.0062 15.2 0.1 1.4 2 0 0 2 2 2 1 Circularly permuted ATP-grasp type 2 DUF427 PF04248.7 KKK25234.1 - 0.027 14.1 0.1 0.058 13.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF427) Mur_ligase_M PF08245.7 KKK25235.1 - 3.8e-06 27.0 1.9 0.00058 19.9 0.6 3.4 2 1 0 2 2 2 1 Mur ligase middle domain NRDE PF05742.7 KKK25236.1 - 2.3e-33 115.6 0.0 7.5e-33 113.9 0.0 1.6 1 1 0 1 1 1 1 NRDE protein Fungal_trans_2 PF11951.3 KKK25237.1 - 5.5e-07 28.5 0.0 1.2e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK25237.1 - 2.1e-05 24.3 12.5 2.1e-05 24.3 8.7 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Lipase_2 PF01674.13 KKK25238.1 - 2.6e-08 33.4 0.1 6.9e-08 32.0 0.0 1.6 2 0 0 2 2 2 1 Lipase (class 2) Abhydrolase_6 PF12697.2 KKK25238.1 - 8.8e-08 32.2 0.4 1.7e-07 31.4 0.3 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KKK25238.1 - 1.7e-05 24.5 0.1 3.2e-05 23.6 0.0 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF1749 PF08538.5 KKK25238.1 - 0.004 16.0 0.0 0.0058 15.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) DUF900 PF05990.7 KKK25238.1 - 0.016 14.5 0.0 0.077 12.3 0.0 1.9 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) PGAP1 PF07819.8 KKK25238.1 - 0.021 14.3 0.0 0.054 13.0 0.0 1.7 1 1 0 1 1 1 0 PGAP1-like protein Abhydrolase_2 PF02230.11 KKK25238.1 - 0.04 13.3 0.0 0.15 11.5 0.0 1.9 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase DUF676 PF05057.9 KKK25238.1 - 0.066 12.4 0.0 0.14 11.4 0.0 1.4 1 1 0 1 1 1 0 Putative serine esterase (DUF676) MFS_1 PF07690.11 KKK25239.1 - 3.5e-17 62.1 28.9 4.9e-10 38.6 6.5 3.3 3 1 1 4 4 4 2 Major Facilitator Superfamily Aldolase_II PF00596.16 KKK25240.1 - 1.7e-48 164.6 0.1 2.1e-48 164.3 0.1 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain GFA PF04828.9 KKK25241.1 - 1.1e-20 73.4 1.2 1.5e-20 72.9 0.8 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme zf-Dof PF02701.10 KKK25241.1 - 0.095 12.6 2.2 4.7 7.2 0.1 2.3 2 0 0 2 2 2 0 Dof domain, zinc finger zf-CSL PF05207.8 KKK25241.1 - 0.9 9.1 6.6 0.33 10.4 0.6 2.2 2 0 0 2 2 2 0 CSL zinc finger LysM PF01476.15 KKK25242.1 - 1e-26 92.5 6.2 2.8e-09 36.7 0.1 4.5 4 0 0 4 4 4 4 LysM domain S-methyl_trans PF02574.11 KKK25243.1 - 6.3e-20 71.6 0.0 2.6e-14 53.2 0.0 2.2 1 1 1 2 2 2 2 Homocysteine S-methyltransferase UPF0113 PF03657.8 KKK25245.1 - 3.3e-07 30.1 0.0 5.1e-07 29.4 0.0 1.5 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0113) Nol1_Nop2_Fmu_2 PF13636.1 KKK25245.1 - 0.026 14.6 0.0 0.06 13.4 0.0 1.6 1 0 0 1 1 1 0 pre-rRNA processing and ribosome biogenesis PUA PF01472.15 KKK25245.1 - 0.065 12.9 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 PUA domain Synaptobrevin PF00957.16 KKK25246.1 - 6.3e-14 51.3 0.2 9.5e-14 50.7 0.1 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 KKK25246.1 - 7.8e-11 41.3 0.0 1.5e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 Regulated-SNARE-like domain Tbf5 PF06331.7 KKK25246.1 - 0.0027 17.4 0.1 0.0064 16.2 0.0 1.6 2 0 0 2 2 2 1 Transcription factor TFIIH complex subunit Tfb5 Phage_Integr_2 PF13009.1 KKK25246.1 - 0.079 11.8 0.1 0.098 11.5 0.0 1.1 1 0 0 1 1 1 0 Putative phage integrase MFS_1 PF07690.11 KKK25247.1 - 1.1e-33 116.4 27.7 1.1e-33 116.4 19.2 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Glyco_hydro_18 PF00704.23 KKK25249.1 - 9.5e-77 258.7 5.3 2.1e-76 257.6 3.7 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.14 KKK25249.1 - 1.6e-07 31.2 9.4 1.6e-07 31.2 6.5 5.5 5 1 0 5 5 5 1 Chitin recognition protein DUF3472 PF11958.3 KKK25250.1 - 3.5e-13 50.2 0.0 4.7e-13 49.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3472) zf-H2C2_2 PF13465.1 KKK25253.1 - 5.3e-14 51.7 35.8 3.4e-08 33.3 0.7 6.3 6 0 0 6 6 6 3 Zinc-finger double domain zf-C2H2 PF00096.21 KKK25253.1 - 2.6e-12 46.2 31.9 1e-06 28.6 1.4 6.3 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-met PF12874.2 KKK25253.1 - 2.1e-08 34.0 10.7 0.00098 19.2 0.2 4.5 3 0 0 3 3 3 3 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 KKK25253.1 - 2.9e-07 30.1 9.2 0.017 14.9 0.3 4.1 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_4 PF13894.1 KKK25253.1 - 1.1e-06 28.5 5.9 0.00058 20.0 0.6 6.5 6 0 0 6 6 6 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KKK25253.1 - 4.6e-05 23.4 12.2 0.01 15.9 0.2 4.5 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding Peptidase_S15 PF02129.13 KKK25254.1 - 0.079 12.3 5.4 0.1 12.0 3.7 1.2 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) DUF4661 PF15576.1 KKK25254.1 - 1.1 8.8 9.8 1.5 8.4 6.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) Nucleo_P87 PF07267.6 KKK25254.1 - 2 6.9 4.5 2.3 6.7 3.1 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DEAD PF00270.24 KKK25255.1 - 4.8e-46 156.3 0.0 1.3e-45 154.8 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KKK25255.1 - 1.4e-24 85.7 0.0 3.7e-24 84.3 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KKK25255.1 - 0.0083 15.9 0.0 0.043 13.6 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 KKK25255.1 - 0.0095 14.7 0.0 0.016 13.9 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain HMG_box PF00505.14 KKK25256.1 - 1e-10 41.6 2.0 1e-10 41.6 1.4 3.3 3 1 0 3 3 3 2 HMG (high mobility group) box HMG_box_2 PF09011.5 KKK25256.1 - 2.8e-09 37.1 15.4 6.4e-08 32.8 0.4 3.1 2 1 0 3 3 3 2 HMG-box domain Sugar_tr PF00083.19 KKK25257.1 - 5.7e-100 335.0 19.3 6.4e-100 334.8 13.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KKK25257.1 - 5e-29 101.1 27.3 1.1e-19 70.3 7.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Alpha-L-AF_C PF06964.7 KKK25258.1 - 1.3e-36 126.0 0.1 2.3e-36 125.2 0.1 1.4 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminus CK_II_beta PF01214.13 KKK25259.1 - 3.9e-71 238.3 0.1 5.4e-71 237.9 0.1 1.2 1 0 0 1 1 1 1 Casein kinase II regulatory subunit Abhydrolase_5 PF12695.2 KKK25260.1 - 1e-05 25.3 0.0 3.1e-05 23.7 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KKK25260.1 - 0.00025 21.0 2.2 0.0007 19.5 1.5 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 KKK25260.1 - 0.0038 16.8 0.1 0.014 15.0 0.0 2.0 2 1 0 2 2 2 1 alpha/beta hydrolase fold DUF4540 PF15073.1 KKK25260.1 - 0.01 16.3 0.3 0.017 15.6 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4540) JAB PF01398.16 KKK25261.1 - 2.9e-08 33.4 0.3 7.6e-07 28.8 0.2 2.4 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease GDE_N PF12439.3 KKK25261.1 - 0.063 12.5 0.4 0.72 9.0 0.1 2.1 2 0 0 2 2 2 0 Glycogen debranching enzyme N terminal Phage_XkdX PF09693.5 KKK25261.1 - 0.063 12.8 0.2 0.17 11.4 0.1 1.7 1 0 0 1 1 1 0 Phage uncharacterised protein (Phage_XkdX) Inhibitor_I78 PF11720.3 KKK25262.1 - 7.4e-14 51.2 0.0 1.3e-13 50.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase inhibitor I78 family potato_inhibit PF00280.13 KKK25262.1 - 0.00035 20.6 0.3 0.00053 20.0 0.2 1.4 1 1 0 1 1 1 1 Potato inhibitor I family Nefa_Nip30_N PF10187.4 KKK25263.1 - 4.3e-32 110.3 12.8 4.3e-32 110.3 8.9 2.3 2 1 0 2 2 2 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 DUF2075 PF09848.4 KKK25263.1 - 0.023 13.6 2.9 0.028 13.4 2.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Aldo_ket_red PF00248.16 KKK25264.1 - 1.3e-45 155.4 0.0 1.5e-45 155.2 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Glyco_hydro_6 PF01341.12 KKK25265.1 - 5.1e-110 367.5 0.6 6.7e-110 367.2 0.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 TPR_11 PF13414.1 KKK25267.1 - 2.9e-20 71.6 9.6 1.6e-16 59.7 3.0 2.5 1 1 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 KKK25267.1 - 8.4e-13 47.3 6.7 0.00063 19.2 0.1 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 KKK25267.1 - 5.1e-12 44.7 9.0 0.0039 17.0 0.6 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 KKK25267.1 - 5.4e-07 30.1 11.6 2.4e-05 24.8 4.7 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 KKK25267.1 - 1.6e-06 27.8 0.8 0.002 18.1 0.3 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 KKK25267.1 - 3.3e-05 23.3 1.2 1.6 8.6 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 KKK25267.1 - 6.2e-05 23.2 4.6 0.00017 21.8 2.0 2.3 1 1 1 2 2 2 1 Tetratricopeptide repeat XPC-binding PF09280.6 KKK25267.1 - 0.00018 20.8 5.5 0.00026 20.3 3.0 1.8 2 0 0 2 2 2 1 XPC-binding domain TPR_14 PF13428.1 KKK25267.1 - 0.00046 20.5 7.3 0.12 13.0 0.2 3.7 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_9 PF13371.1 KKK25267.1 - 0.00052 19.8 4.7 0.015 15.1 0.1 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 KKK25267.1 - 0.0011 18.8 7.6 0.11 12.3 0.7 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 KKK25267.1 - 0.0011 18.5 8.1 0.065 13.0 0.1 4.1 3 1 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.1 KKK25267.1 - 5.1 7.1 8.9 1.7 8.6 0.5 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 KKK25267.1 - 9.3 6.9 8.8 6 7.5 0.2 3.7 4 0 0 4 4 3 0 Tetratricopeptide repeat Mito_carr PF00153.22 KKK25268.1 - 1.1e-67 223.7 1.8 7.9e-24 83.1 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein GFA PF04828.9 KKK25269.1 - 3.4e-11 42.9 1.6 5.3e-11 42.3 1.1 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Mod_r PF07200.8 KKK25270.1 - 1.4e-09 37.9 3.5 2e-09 37.5 2.4 1.1 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein EF-hand_like PF09279.6 KKK25270.1 - 0.23 11.5 1.0 0.68 9.9 0.1 2.1 2 1 0 2 2 2 0 Phosphoinositide-specific phospholipase C, efhand-like Na_H_Exchanger PF00999.16 KKK25271.1 - 3.5e-70 236.4 46.6 4.6e-70 236.0 32.3 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Usp PF00582.21 KKK25271.1 - 0.021 15.0 0.0 0.29 11.3 0.0 2.6 2 1 0 2 2 2 0 Universal stress protein family CHCH PF06747.8 KKK25272.1 - 0.00024 20.9 1.0 0.00036 20.3 0.7 1.3 1 0 0 1 1 1 1 CHCH domain Pet191_N PF10203.4 KKK25272.1 - 0.015 15.3 2.0 0.14 12.1 1.5 2.0 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 COX17 PF05051.8 KKK25272.1 - 0.057 13.4 3.0 0.5 10.4 0.2 2.2 1 1 1 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) ANKH PF07260.6 KKK25272.1 - 0.14 11.1 0.0 0.17 10.8 0.0 1.1 1 0 0 1 1 1 0 Progressive ankylosis protein (ANKH) Got1 PF04178.7 KKK25273.1 - 4.2e-30 104.2 15.8 2.2e-29 101.9 10.9 1.9 1 1 0 1 1 1 1 Got1/Sft2-like family Peptidase_M50 PF02163.17 KKK25273.1 - 0.0017 17.3 0.0 0.0026 16.7 0.0 1.5 1 1 0 1 1 1 1 Peptidase family M50 HLH PF00010.21 KKK25274.1 - 1.2e-12 47.2 0.0 3.6e-12 45.7 0.0 1.8 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain Ank_5 PF13857.1 KKK25275.1 - 8.4e-12 44.9 0.1 5.7e-09 35.9 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 KKK25275.1 - 5.8e-11 42.6 0.1 7.1e-07 29.5 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 KKK25275.1 - 1.2e-06 28.7 0.2 5.1e-06 26.7 0.2 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 KKK25275.1 - 3.3e-06 26.8 0.8 3e-05 23.8 0.1 2.6 2 1 0 2 2 2 1 Ankyrin repeat Ank PF00023.25 KKK25275.1 - 2.7e-05 23.7 1.8 0.00066 19.3 0.1 3.2 3 1 0 3 3 3 1 Ankyrin repeat YejG PF13989.1 KKK25275.1 - 0.0087 16.1 0.0 0.015 15.3 0.0 1.3 1 0 0 1 1 1 1 YejG-like protein tRNA_lig_CPD PF08302.6 KKK25276.1 - 7.5e-89 297.3 0.0 1e-88 296.8 0.0 1.2 1 0 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain RNA_lig_T4_1 PF09511.5 KKK25276.1 - 3.7e-81 271.8 0.0 9.7e-81 270.4 0.0 1.8 1 0 0 1 1 1 1 RNA ligase tRNA_lig_kinase PF08303.6 KKK25276.1 - 1.9e-52 177.5 0.0 3.3e-52 176.7 0.0 1.4 1 0 0 1 1 1 1 tRNA ligase kinase domain AAA_33 PF13671.1 KKK25276.1 - 0.057 13.2 0.0 0.19 11.5 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.1 KKK25276.1 - 0.1 13.4 0.0 0.5 11.1 0.0 2.3 1 1 0 1 1 1 0 AAA domain NPR3 PF03666.8 KKK25277.1 - 5.9e-137 456.8 1.6 1.6e-135 452.1 0.0 2.1 2 0 0 2 2 2 1 Nitrogen Permease regulator of amino acid transport activity 3 Myc_N PF01056.13 KKK25277.1 - 0.0028 16.9 1.2 0.0065 15.6 0.8 1.5 1 0 0 1 1 1 1 Myc amino-terminal region NPR2 PF06218.6 KKK25277.1 - 0.063 11.9 0.0 0.13 10.9 0.0 1.4 1 0 0 1 1 1 0 Nitrogen permease regulator 2 NST1 PF13945.1 KKK25277.1 - 0.16 12.0 8.2 0.45 10.5 0.1 2.4 2 0 0 2 2 2 0 Salt tolerance down-regulator BLVR PF06375.6 KKK25277.1 - 1.4 8.7 13.5 1.3 8.8 2.2 3.1 3 0 0 3 3 3 0 Bovine leukaemia virus receptor (BLVR) La PF05383.12 KKK25278.1 - 1.2e-19 69.8 0.4 2.3e-19 68.9 0.3 1.4 1 0 0 1 1 1 1 La domain TatD_DNase PF01026.16 KKK25279.1 - 4.8e-47 160.3 0.0 6.4e-47 159.8 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase Sox_C_TAD PF12067.3 KKK25279.1 - 0.12 12.5 0.0 0.19 11.8 0.0 1.2 1 0 0 1 1 1 0 Sox C-terminal transactivation domain Ank_5 PF13857.1 KKK25280.1 - 9.4e-19 67.0 0.1 6.4e-10 38.9 0.0 5.7 7 0 0 7 7 7 3 Ankyrin repeats (many copies) VPS9 PF02204.13 KKK25280.1 - 7.6e-16 58.0 0.0 1.7e-15 56.9 0.0 1.5 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Ank_2 PF12796.2 KKK25280.1 - 2.4e-13 50.2 0.1 1.4e-08 34.9 0.1 3.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KKK25280.1 - 2.4e-09 37.4 0.1 0.012 16.1 0.0 4.9 2 1 2 4 4 4 3 Ankyrin repeats (many copies) PX PF00787.19 KKK25280.1 - 5.4e-09 35.8 3.1 5.9e-09 35.7 0.4 2.3 2 0 0 2 2 2 1 PX domain Ank_3 PF13606.1 KKK25280.1 - 6.7e-09 35.1 0.2 0.65 10.4 0.0 5.8 5 0 0 5 5 5 3 Ankyrin repeat Ank PF00023.25 KKK25280.1 - 4.1e-07 29.4 0.3 0.11 12.3 0.0 5.1 6 0 0 6 6 6 2 Ankyrin repeat Ribosomal_S11 PF00411.14 KKK25280.1 - 0.0005 20.2 0.0 0.0017 18.5 0.0 1.9 1 0 0 1 1 1 1 Ribosomal protein S11 FAST_2 PF08368.7 KKK25280.1 - 0.068 13.5 0.0 0.24 11.8 0.0 2.0 1 0 0 1 1 1 0 FAST kinase-like protein, subdomain 2 Tim44 PF04280.10 KKK25281.1 - 3.9e-34 117.7 0.1 1.3e-33 116.0 0.0 1.8 2 0 0 2 2 2 1 Tim44-like domain CutA1 PF03091.10 KKK25281.1 - 0.11 12.1 0.0 0.38 10.4 0.0 1.9 2 0 0 2 2 2 0 CutA1 divalent ion tolerance protein RIC1 PF07064.8 KKK25282.1 - 4.8e-91 304.7 0.0 6.8e-91 304.2 0.0 1.2 1 0 0 1 1 1 1 RIC1 YchF-GTPase_C PF06071.8 KKK25283.1 - 7.3e-32 109.0 1.0 1.6e-31 107.9 0.1 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF933) PUA PF01472.15 KKK25283.1 - 3.5e-14 52.2 0.1 1.1e-13 50.7 0.1 1.9 1 0 0 1 1 1 1 PUA domain MMR_HSR1 PF01926.18 KKK25283.1 - 1.5e-12 47.5 0.0 3.4e-12 46.3 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KKK25283.1 - 0.00038 19.7 0.0 0.00075 18.8 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B TGS PF02824.16 KKK25283.1 - 0.0029 17.4 0.1 0.016 14.9 0.1 2.2 2 0 0 2 2 2 1 TGS domain AAA_14 PF13173.1 KKK25283.1 - 0.031 14.1 0.0 0.094 12.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain SecA_PP_bind PF01043.15 KKK25283.1 - 0.041 14.2 0.3 0.2 12.0 0.0 2.1 1 1 1 2 2 2 0 SecA preprotein cross-linking domain Hira PF07569.6 KKK25284.1 - 1.2e-83 279.6 0.0 2.2e-83 278.8 0.0 1.4 1 0 0 1 1 1 1 TUP1-like enhancer of split WD40 PF00400.27 KKK25284.1 - 8.1e-36 120.6 16.3 1.4e-07 31.1 0.0 8.6 8 0 0 8 8 8 6 WD domain, G-beta repeat HIRA_B PF09453.5 KKK25284.1 - 1.5e-10 40.3 0.1 3.5e-10 39.1 0.1 1.7 1 0 0 1 1 1 1 HIRA B motif PD40 PF07676.7 KKK25284.1 - 5.6e-05 22.6 0.9 1.7 8.4 0.0 5.1 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat IKI3 PF04762.7 KKK25284.1 - 0.076 10.8 0.0 0.44 8.3 0.0 1.9 2 0 0 2 2 2 0 IKI3 family Band_7 PF01145.20 KKK25285.1 - 4.6e-31 108.1 0.6 1e-30 106.9 0.4 1.5 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.1 KKK25285.1 - 0.018 14.5 0.0 0.035 13.6 0.0 1.6 1 1 0 1 1 1 0 SPFH domain-Band 7 family HSP70 PF00012.15 KKK25354.1 - 2.8e-262 871.0 12.7 3.2e-262 870.8 8.8 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KKK25354.1 - 2.7e-17 62.3 2.0 3.3e-16 58.8 0.5 2.1 2 0 0 2 2 2 1 MreB/Mbl protein DDR PF08841.5 KKK25354.1 - 0.0053 15.6 1.4 0.021 13.7 0.9 1.9 1 1 0 1 1 1 1 Diol dehydratase reactivase ATPase-like domain Hydantoinase_A PF01968.13 KKK25354.1 - 0.048 12.7 6.0 0.059 12.4 0.2 3.1 3 1 0 3 3 3 0 Hydantoinase/oxoprolinase FtsA PF14450.1 KKK25354.1 - 6.5 6.6 7.4 5.4 6.8 0.8 3.4 2 2 0 2 2 2 0 Cell division protein FtsA DUF3154 PF11351.3 KKK25354.1 - 7.1 6.4 6.8 1.7 8.3 0.0 3.0 4 0 0 4 4 4 0 Protein of unknown function (DUF3154) DUF336 PF03928.9 KKK25355.1 - 1.4e-14 53.9 2.1 7.7e-13 48.3 1.4 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF336) GTP_EFTU PF00009.22 KKK25356.1 - 2.1e-51 174.0 0.1 3.5e-51 173.3 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain HBS1_N PF08938.5 KKK25356.1 - 1.2e-14 54.1 4.5 2.5e-14 53.1 3.1 1.5 1 0 0 1 1 1 1 HBS1 N-terminus MMR_HSR1 PF01926.18 KKK25356.1 - 3.2e-08 33.5 0.2 2.9e-07 30.4 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.20 KKK25356.1 - 1.1e-07 31.7 0.0 3.8e-07 30.1 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D3 PF03143.12 KKK25356.1 - 2.4e-06 27.6 0.0 8.7e-06 25.8 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain Gtr1_RagA PF04670.7 KKK25356.1 - 7.2e-05 22.0 0.1 0.00024 20.3 0.1 1.8 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 KKK25356.1 - 0.00034 19.8 0.1 0.035 13.3 0.1 2.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 KKK25356.1 - 0.0013 19.2 0.1 0.0073 16.7 0.0 2.4 1 1 0 1 1 1 1 Miro-like protein Arf PF00025.16 KKK25356.1 - 0.0071 15.6 0.2 2.1 7.5 0.0 2.4 1 1 1 2 2 2 2 ADP-ribosylation factor family FeoB_N PF02421.13 KKK25356.1 - 0.023 13.9 0.6 0.72 9.1 0.2 2.8 2 1 0 2 2 2 0 Ferrous iron transport protein B Septin PF00735.13 KKK25356.1 - 0.03 13.3 0.0 0.052 12.5 0.0 1.4 1 0 0 1 1 1 0 Septin Na_Ca_ex PF01699.19 KKK25371.1 - 7.1e-44 148.8 32.8 9.6e-23 80.3 9.7 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Fungal_trans PF04082.13 KKK25372.1 - 1.5e-19 69.9 0.0 3.4e-19 68.7 0.0 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK25372.1 - 4.8e-05 23.1 7.6 9.3e-05 22.2 5.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RVP PF00077.15 KKK25373.1 - 0.016 15.1 0.1 0.029 14.3 0.1 1.5 1 1 0 1 1 1 0 Retroviral aspartyl protease Asp_protease_2 PF13650.1 KKK25373.1 - 0.033 14.6 0.0 0.062 13.8 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease PIG-X PF08320.7 KKK25380.1 - 3.9e-77 258.2 0.0 5.3e-77 257.7 0.0 1.2 1 0 0 1 1 1 1 PIG-X / PBN1 Fungal_trans PF04082.13 KKK25381.1 - 2e-11 43.2 0.0 3.5e-11 42.4 0.0 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK25381.1 - 1.4e-08 34.5 9.6 2.3e-08 33.7 6.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SoxE PF06525.6 KKK25381.1 - 0.67 9.2 4.5 1.1 8.4 3.1 1.3 1 0 0 1 1 1 0 Sulfocyanin (SoxE) CTDII PF01556.13 KKK25382.1 - 5.6e-25 87.0 0.5 2.7e-22 78.4 0.0 2.8 2 1 0 2 2 2 2 DnaJ C terminal domain HGTP_anticodon2 PF12745.2 KKK25383.1 - 1.1e-83 280.5 0.5 1.9e-83 279.7 0.4 1.4 1 1 0 1 1 1 1 Anticodon binding domain of tRNAs Pkinase PF00069.20 KKK25383.1 - 5.5e-34 117.4 0.0 1.1e-33 116.4 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK25383.1 - 3.3e-17 62.4 0.0 5.8e-17 61.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase tRNA-synt_His PF13393.1 KKK25383.1 - 2.7e-11 43.1 0.0 4.9e-11 42.2 0.0 1.4 1 0 0 1 1 1 1 Histidyl-tRNA synthetase APH PF01636.18 KKK25383.1 - 0.00082 19.1 0.2 0.0021 17.8 0.1 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 KKK25383.1 - 0.036 13.0 0.0 0.074 12.0 0.0 1.4 1 0 0 1 1 1 0 Kinase-like HGTP_anticodon PF03129.15 KKK25383.1 - 0.067 13.1 0.0 0.18 11.7 0.0 1.7 1 0 0 1 1 1 0 Anticodon binding domain TGS PF02824.16 KKK25385.1 - 1.1e-20 73.2 0.1 1.9e-20 72.4 0.1 1.4 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 KKK25385.1 - 2.1e-19 69.5 0.1 1.1e-18 67.2 0.1 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KKK25385.1 - 6.8e-12 44.9 0.0 1.1e-11 44.2 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 KKK25385.1 - 7e-05 22.7 0.2 0.064 13.0 0.0 2.4 1 1 1 2 2 2 2 Dynamin family Miro PF08477.8 KKK25385.1 - 0.0015 18.9 0.0 0.0048 17.3 0.0 1.9 2 0 0 2 2 2 1 Miro-like protein AIG1 PF04548.11 KKK25385.1 - 0.022 13.8 0.0 0.036 13.1 0.0 1.3 1 0 0 1 1 1 0 AIG1 family ArgK PF03308.11 KKK25385.1 - 0.027 13.2 0.1 0.058 12.1 0.1 1.6 1 0 0 1 1 1 0 ArgK protein MCM PF00493.18 KKK25385.1 - 0.037 12.8 0.0 0.071 11.9 0.0 1.4 1 0 0 1 1 1 0 MCM2/3/5 family AAA_17 PF13207.1 KKK25385.1 - 0.23 12.2 1.0 1.6 9.6 0.7 2.3 1 1 0 1 1 1 0 AAA domain RRM_1 PF00076.17 KKK25386.1 - 1e-08 34.7 0.0 2.1e-08 33.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KKK25386.1 - 2.2e-06 27.3 0.0 4.4e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KKK25386.1 - 3.7e-05 23.6 0.0 6.6e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KKK25386.1 - 0.012 15.3 0.0 0.024 14.3 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif zf-CCCH PF00642.19 KKK25386.1 - 0.14 11.9 1.7 0.23 11.1 1.2 1.4 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) CPSase_sm_chain PF00988.17 KKK25388.1 - 5.5e-46 155.2 0.0 9.6e-46 154.5 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.23 KKK25388.1 - 6.9e-46 156.1 0.0 9.5e-46 155.6 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 KKK25388.1 - 4.5e-06 26.2 0.1 0.00019 20.9 0.0 2.4 1 1 0 1 1 1 1 Peptidase C26 DUF1250 PF06855.7 KKK25388.1 - 0.14 11.6 0.0 1.6 8.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1250) S4 PF01479.20 KKK25410.1 - 1.4e-12 46.8 0.0 2.6e-12 45.9 0.0 1.5 1 0 0 1 1 1 1 S4 domain Occludin_ELL PF07303.8 KKK25410.1 - 0.0077 16.9 0.1 0.018 15.7 0.1 1.7 1 1 0 1 1 1 1 Occludin homology domain PilP PF04351.8 KKK25410.1 - 0.047 13.5 0.1 0.087 12.7 0.0 1.5 1 0 0 1 1 1 0 Pilus assembly protein, PilP COG2 PF06148.6 KKK25410.1 - 0.08 12.8 0.2 0.21 11.4 0.0 1.9 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF4449 PF14613.1 KKK25411.1 - 0.00046 20.1 1.7 0.00094 19.1 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF4449) Tricorn_C1 PF14684.1 KKK25411.1 - 0.00052 19.8 0.2 0.0017 18.1 0.1 2.0 1 0 0 1 1 1 1 Tricorn protease C1 domain FCD PF07729.7 KKK25411.1 - 0.018 15.3 0.7 0.018 15.3 0.5 3.1 2 1 1 3 3 3 0 FCD domain Pox_C4_C10 PF03336.8 KKK25411.1 - 0.085 11.6 0.0 0.14 10.9 0.0 1.3 1 0 0 1 1 1 0 Poxvirus C4/C10 protein Gp-FAR-1 PF05823.7 KKK25411.1 - 0.087 12.7 0.3 0.27 11.1 0.1 1.9 1 1 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Rho_Binding PF08912.6 KKK25411.1 - 1.4 9.2 6.0 4.9 7.5 0.0 3.5 3 1 0 3 3 3 0 Rho Binding DnaJ PF00226.26 KKK25412.1 - 6.6e-27 93.0 2.0 1.1e-26 92.3 1.4 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 KKK25412.1 - 2.3e-17 62.7 14.1 3.9e-17 62.0 9.8 1.4 1 0 0 1 1 1 1 DnaJ central domain CTDII PF01556.13 KKK25412.1 - 3.5e-10 39.6 0.0 2e-09 37.2 0.0 2.3 3 0 0 3 3 3 1 DnaJ C terminal domain HypA PF01155.14 KKK25412.1 - 0.053 13.1 5.1 0.22 11.2 0.1 2.2 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family zf-CSL PF05207.8 KKK25412.1 - 0.15 11.5 3.9 1.2 8.7 0.5 2.4 2 0 0 2 2 2 0 CSL zinc finger GRP PF07172.6 KKK25412.1 - 3.7 8.0 8.8 15 6.1 6.1 2.0 1 1 0 1 1 1 0 Glycine rich protein family Glyco_hydro_3 PF00933.16 KKK25434.1 - 3.6e-96 321.6 0.0 5.1e-96 321.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KKK25434.1 - 9e-55 185.6 0.3 1.6e-53 181.5 0.0 2.2 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KKK25434.1 - 4.7e-12 45.6 0.1 9.7e-12 44.6 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain DUF2628 PF10947.3 KKK25434.1 - 9.1 6.1 14.8 5.4 6.8 4.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2628) bZIP_1 PF00170.16 KKK25435.1 - 0.0052 16.7 11.3 0.034 14.0 7.8 2.0 1 1 1 2 2 2 1 bZIP transcription factor PV-1 PF06637.6 KKK25435.1 - 0.36 9.3 4.8 0.54 8.7 3.4 1.1 1 0 0 1 1 1 0 PV-1 protein (PLVAP) Gluconate_2-dh3 PF13618.1 KKK25450.1 - 0.00073 19.6 2.1 0.0015 18.6 1.4 1.5 1 0 0 1 1 1 1 Gluconate 2-dehydrogenase subunit 3 Exo_endo_phos PF03372.18 KKK25451.1 - 7.6e-18 65.3 0.2 1.2e-17 64.7 0.1 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DCP1 PF06058.8 KKK25452.1 - 1.8e-16 60.3 0.0 1.5e-15 57.3 0.0 2.0 1 1 0 1 1 1 1 Dcp1-like decapping family DUF2305 PF10230.4 KKK25453.1 - 1.4e-77 260.7 0.0 9.1e-77 258.0 0.0 1.9 1 1 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Abhydrolase_6 PF12697.2 KKK25453.1 - 6.5e-08 32.7 0.6 1.1e-06 28.7 0.4 2.1 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KKK25453.1 - 9.2e-06 25.4 0.0 7.8e-05 22.4 0.0 2.2 2 1 0 2 2 2 1 Alpha/beta hydrolase family DUF1057 PF06342.7 KKK25453.1 - 0.019 13.7 0.0 0.35 9.6 0.0 2.2 1 1 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) Abhydrolase_1 PF00561.15 KKK25453.1 - 0.02 14.4 0.1 0.25 10.8 0.0 2.4 3 1 0 3 3 3 0 alpha/beta hydrolase fold DUF900 PF05990.7 KKK25453.1 - 0.027 13.7 0.0 0.055 12.7 0.0 1.5 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) Thioesterase PF00975.15 KKK25453.1 - 0.064 13.4 0.0 0.31 11.2 0.0 2.1 2 0 0 2 2 2 0 Thioesterase domain PGAP1 PF07819.8 KKK25453.1 - 0.11 12.0 0.1 0.31 10.5 0.0 1.7 2 0 0 2 2 2 0 PGAP1-like protein SMK-1 PF04802.10 KKK25454.1 - 2.4e-75 252.3 1.8 3.9e-75 251.6 1.3 1.4 1 0 0 1 1 1 1 Component of IIS longevity pathway SMK-1 GalKase_gal_bdg PF10509.4 KKK25454.1 - 0.12 11.6 0.0 0.26 10.6 0.0 1.5 1 0 0 1 1 1 0 Galactokinase galactose-binding signature Arm PF00514.18 KKK25467.1 - 1e-93 304.3 10.2 3.6e-14 51.9 0.0 8.3 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 KKK25467.1 - 1.9e-24 85.7 0.1 4.6e-10 39.6 0.0 5.7 1 1 6 7 7 7 4 HEAT repeats IBB PF01749.15 KKK25467.1 - 2.2e-21 75.8 3.9 4.2e-21 74.9 2.7 1.5 1 0 0 1 1 1 1 Importin beta binding domain HEAT PF02985.17 KKK25467.1 - 4.7e-21 72.9 0.1 1.1e-06 28.1 0.0 7.0 7 0 0 7 7 7 4 HEAT repeat HEAT_EZ PF13513.1 KKK25467.1 - 1.8e-20 72.7 8.8 4.4e-10 39.7 0.1 6.0 5 1 2 7 7 7 3 HEAT-like repeat Arm_2 PF04826.8 KKK25467.1 - 7.2e-12 44.9 0.0 0.00079 18.6 0.0 4.4 3 1 2 5 5 5 3 Armadillo-like Adaptin_N PF01602.15 KKK25467.1 - 1.6e-06 26.7 0.0 0.00034 19.0 0.0 2.3 1 1 1 2 2 2 2 Adaptin N terminal region V-ATPase_H_C PF11698.3 KKK25467.1 - 5.7e-05 23.0 0.0 0.61 10.0 0.0 4.5 3 2 2 5 5 5 1 V-ATPase subunit H Proteasom_PSMB PF10508.4 KKK25467.1 - 0.0024 16.2 0.0 0.74 8.0 0.0 3.0 2 1 1 3 3 3 2 Proteasome non-ATPase 26S subunit HEAT_PBS PF03130.11 KKK25467.1 - 0.0076 16.6 4.7 0.64 10.6 0.0 4.6 5 0 0 5 5 5 1 PBS lyase HEAT-like repeat Glycos_trans_3N PF02885.12 KKK25467.1 - 0.023 14.2 0.0 31 4.2 0.0 3.4 3 0 0 3 3 3 0 Glycosyl transferase family, helical bundle domain Mo25 PF08569.6 KKK25467.1 - 0.12 11.3 0.0 0.24 10.4 0.0 1.5 1 0 0 1 1 1 0 Mo25-like Haemadin PF09065.5 KKK25468.1 - 0.028 13.9 4.7 3.6 7.2 0.1 3.0 2 1 0 2 2 2 0 Haemadin TRAP_alpha PF03896.11 KKK25469.1 - 1.1e-11 44.2 2.7 3.5e-11 42.6 1.9 1.7 1 1 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit DcpS_C PF11969.3 KKK25470.1 - 6.1e-16 58.6 4.9 9.8e-15 54.8 3.4 2.1 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.18 KKK25470.1 - 1.2e-15 57.7 0.0 2.9e-15 56.6 0.0 1.6 1 1 0 1 1 1 1 HIT domain HA2 PF04408.18 KKK25471.1 - 3.6e-19 68.6 0.0 1.1e-18 67.0 0.0 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 KKK25471.1 - 3.4e-16 59.0 0.0 6.8e-16 58.1 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold RWD PF05773.17 KKK25471.1 - 1.8e-12 47.1 0.2 4.6e-12 45.8 0.0 1.8 2 0 0 2 2 2 1 RWD domain Helicase_C PF00271.26 KKK25471.1 - 2.1e-12 46.7 0.0 1.3e-11 44.1 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 KKK25471.1 - 9.3e-10 38.2 0.1 1.7e-09 37.3 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase T2SE PF00437.15 KKK25471.1 - 0.00039 19.4 0.0 0.0008 18.3 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.1 KKK25471.1 - 0.00044 20.3 0.8 0.0017 18.5 0.5 1.9 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 KKK25471.1 - 0.0033 16.9 0.0 0.0077 15.7 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain KaiC PF06745.8 KKK25471.1 - 0.016 14.3 0.1 0.031 13.3 0.0 1.4 1 0 0 1 1 1 0 KaiC DND1_DSRM PF14709.1 KKK25471.1 - 0.028 14.7 0.4 0.12 12.6 0.3 2.2 1 1 0 1 1 1 0 double strand RNA binding domain from DEAD END PROTEIN 1 AAA_25 PF13481.1 KKK25471.1 - 0.031 13.6 0.0 0.25 10.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain Zot PF05707.7 KKK25471.1 - 0.038 13.4 0.0 0.081 12.3 0.0 1.5 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) PhoH PF02562.11 KKK25471.1 - 0.047 12.9 0.0 0.091 11.9 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_23 PF13476.1 KKK25471.1 - 0.2 11.9 1.6 0.21 11.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain Podovirus_Gp16 PF05894.7 KKK25471.1 - 0.25 10.6 0.0 0.51 9.6 0.0 1.4 1 0 0 1 1 1 0 Podovirus DNA encapsidation protein (Gp16) Cyclin_N PF00134.18 KKK25472.1 - 8.2e-44 148.2 0.2 1.6e-43 147.2 0.2 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 KKK25472.1 - 3.4e-29 101.1 0.2 1.1e-28 99.5 0.1 1.9 1 0 0 1 1 1 1 Cyclin, C-terminal domain Zn_clus PF00172.13 KKK25473.1 - 0.0014 18.4 12.2 0.0028 17.5 8.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CHZ PF09649.5 KKK25473.1 - 0.08 12.1 0.0 0.21 10.8 0.0 1.7 1 0 0 1 1 1 0 Histone chaperone domain CHZ GTP_EFTU PF00009.22 KKK25479.1 - 3e-41 140.9 0.2 3.3e-41 140.7 0.1 1.0 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KKK25479.1 - 0.00036 20.4 0.1 0.001 19.0 0.1 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase Septin PF00735.13 KKK25479.1 - 0.032 13.2 0.1 0.092 11.7 0.0 1.6 1 1 0 1 1 1 0 Septin AIG1 PF04548.11 KKK25479.1 - 0.033 13.2 0.6 0.39 9.7 0.4 2.0 1 1 0 1 1 1 0 AIG1 family Dynamin_N PF00350.18 KKK25479.1 - 0.036 13.8 0.1 1.9 8.2 0.0 2.1 2 0 0 2 2 2 0 Dynamin family SRPRB PF09439.5 KKK25479.1 - 0.038 13.2 0.1 0.44 9.7 0.0 2.1 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Miro PF08477.8 KKK25479.1 - 0.054 13.9 0.4 0.65 10.5 0.3 2.0 1 1 0 1 1 1 0 Miro-like protein MobB PF03205.9 KKK25479.1 - 0.073 12.7 0.1 0.12 12.0 0.1 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Fibrinogen_aC PF12160.3 KKK25479.1 - 0.075 12.5 0.2 0.38 10.2 0.0 2.0 2 0 0 2 2 2 0 Fibrinogen alpha C domain PduV-EutP PF10662.4 KKK25479.1 - 0.093 12.2 0.1 7.2 6.0 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation G-alpha PF00503.15 KKK25479.1 - 0.12 11.0 0.1 0.21 10.2 0.0 1.4 2 0 0 2 2 2 0 G-protein alpha subunit Polyoma_lg_T_C PF06431.6 KKK25479.1 - 0.15 10.6 0.0 0.2 10.3 0.0 1.2 1 0 0 1 1 1 0 Polyomavirus large T antigen C-terminus Ank_2 PF12796.2 KKK25480.1 - 3.4e-13 49.7 0.1 8.1e-09 35.7 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KKK25480.1 - 1.4e-09 37.2 0.0 2.4e-05 23.8 0.0 2.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.1 KKK25480.1 - 4.9e-09 35.5 0.0 0.0017 18.4 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 KKK25480.1 - 3.8e-08 33.3 0.1 0.081 13.2 0.0 3.4 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 KKK25480.1 - 1.1e-05 25.8 0.6 0.004 17.6 0.1 2.8 1 1 2 3 3 3 3 Ankyrin repeats (many copies) TFIIS_C PF01096.13 KKK25481.1 - 8.7e-14 50.8 2.5 2.1e-13 49.6 0.1 2.1 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 KKK25481.1 - 0.026 14.2 0.5 0.052 13.2 0.1 1.7 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit zf-C2HC PF01530.13 KKK25481.1 - 3.3 7.4 4.8 1.3 8.7 0.5 2.1 2 0 0 2 2 2 0 Zinc finger, C2HC type MAGE PF01454.14 KKK25482.1 - 1.1e-26 93.3 0.0 1.8e-26 92.7 0.0 1.3 1 0 0 1 1 1 1 MAGE family F-actin_cap_A PF01267.12 KKK25484.1 - 1.1e-91 306.6 0.0 1.5e-91 306.2 0.0 1.1 1 0 0 1 1 1 1 F-actin capping protein alpha subunit PEX11 PF05648.9 KKK25484.1 - 3.6e-30 104.9 0.1 1.6e-29 102.7 0.1 2.1 1 1 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) DUF3987 PF13148.1 KKK25484.1 - 0.067 11.7 0.0 0.13 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Fungal_trans PF04082.13 KKK25485.1 - 1.8e-08 33.6 0.4 2.7e-08 32.9 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK25485.1 - 3.2e-07 30.1 10.8 7.3e-07 28.9 7.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HEAT PF02985.17 KKK25486.1 - 2.9e-22 76.7 0.9 7.9e-05 22.4 0.1 9.5 8 0 0 8 8 8 3 HEAT repeat HEAT_EZ PF13513.1 KKK25486.1 - 2.8e-20 72.1 10.0 2.3e-05 24.7 0.0 9.9 9 2 3 12 12 10 5 HEAT-like repeat HEAT_2 PF13646.1 KKK25486.1 - 8.4e-20 70.8 7.9 0.00011 22.3 0.0 7.6 5 3 3 8 8 8 5 HEAT repeats Cnd1 PF12717.2 KKK25486.1 - 5.1e-12 45.9 0.9 0.0013 18.5 0.1 4.1 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 IBN_N PF03810.14 KKK25486.1 - 5.5e-10 39.0 0.5 2e-07 30.8 0.0 3.9 4 0 0 4 4 4 1 Importin-beta N-terminal domain Vac14_Fab1_bd PF12755.2 KKK25486.1 - 1.6e-09 38.0 0.1 0.35 11.2 0.0 5.8 4 1 1 5 5 5 2 Vacuolar 14 Fab1-binding region CLASP_N PF12348.3 KKK25486.1 - 4.5e-07 29.4 0.0 0.033 13.5 0.0 3.8 3 1 0 3 3 3 2 CLASP N terminal MMS19_C PF12460.3 KKK25486.1 - 1.7e-06 27.0 0.8 0.00061 18.6 0.0 3.3 3 0 0 3 3 3 1 RNAPII transcription regulator C-terminal Arm PF00514.18 KKK25486.1 - 5.6e-06 25.9 0.2 3 7.8 0.0 5.3 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.15 KKK25486.1 - 7.3e-05 21.2 0.1 0.14 10.4 0.0 3.1 3 0 0 3 3 3 2 Adaptin N terminal region ParcG PF10274.4 KKK25486.1 - 0.00071 19.5 0.5 0.042 13.7 0.1 3.2 3 1 1 4 4 4 1 Parkin co-regulated protein UME PF08064.8 KKK25486.1 - 0.00096 19.0 0.0 0.88 9.5 0.0 4.2 4 1 1 5 5 5 1 UME (NUC010) domain DUF577 PF04510.7 KKK25486.1 - 0.0032 17.1 0.0 0.032 13.9 0.0 2.6 3 0 0 3 3 3 1 Family of unknown function (DUF577) Cohesin_HEAT PF12765.2 KKK25486.1 - 0.026 14.4 0.0 2.2 8.3 0.0 3.1 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion Sec7_N PF12783.2 KKK25486.1 - 0.081 12.3 0.0 0.46 9.8 0.0 2.3 3 0 0 3 3 3 0 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF4042 PF13251.1 KKK25486.1 - 0.097 12.1 0.1 1.5 8.2 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4042) Pkinase PF00069.20 KKK25487.1 - 3e-23 82.2 0.0 1.3e-22 80.1 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK25487.1 - 9.2e-06 24.9 0.0 2.1e-05 23.7 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Candida_ALS_N PF11766.3 KKK25487.1 - 0.089 11.6 0.0 0.13 11.1 0.0 1.1 1 0 0 1 1 1 0 Cell-wall agglutinin N-terminal ligand-sugar binding Ras PF00071.17 KKK25488.1 - 2.6e-31 108.1 0.2 3.3e-31 107.8 0.2 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KKK25488.1 - 2.4e-20 73.1 0.1 8.4e-20 71.4 0.0 1.8 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 KKK25488.1 - 9.8e-07 28.1 0.1 1.3e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KKK25488.1 - 4.3e-05 22.7 0.2 5.5e-05 22.4 0.2 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KKK25488.1 - 0.075 12.9 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase G-alpha PF00503.15 KKK25488.1 - 0.23 10.1 0.0 0.23 10.1 0.0 2.2 2 1 1 3 3 3 0 G-protein alpha subunit Pex14_N PF04695.8 KKK25488.1 - 1.5 8.8 8.6 3.7 7.5 5.9 1.7 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region 2-Hacid_dh PF00389.25 KKK25489.1 - 1.6e-06 27.6 0.0 1.8e-06 27.4 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain DUF3431 PF11913.3 KKK25490.1 - 2.8e-75 252.6 0.0 3.3e-75 252.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) Recep_L_domain PF01030.19 KKK25491.1 - 6.1e-05 22.9 0.0 0.00013 21.8 0.0 1.6 1 1 0 1 1 1 1 Receptor L domain Myc_target_1 PF15179.1 KKK25491.1 - 0.021 14.4 0.0 0.036 13.6 0.0 1.4 1 0 0 1 1 1 0 Myc target protein 1 Ecm33 PF12454.3 KKK25491.1 - 0.035 13.9 1.9 0.038 13.8 0.1 2.1 2 0 0 2 2 2 0 GPI-anchored cell wall organization protein VSP PF03302.8 KKK25491.1 - 0.042 12.4 0.3 0.063 11.8 0.2 1.2 1 0 0 1 1 1 0 Giardia variant-specific surface protein Rifin_STEVOR PF02009.11 KKK25491.1 - 0.048 13.3 0.0 0.074 12.6 0.0 1.2 1 0 0 1 1 1 0 Rifin/stevor family FA_desaturase PF00487.19 KKK25492.1 - 4e-29 101.8 24.1 5.6e-29 101.3 16.7 1.1 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.3 KKK25492.1 - 0.051 13.5 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3474) WD40 PF00400.27 KKK25493.1 - 3.6e-28 96.4 7.4 1.2e-10 40.8 0.1 4.6 4 0 0 4 4 4 4 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 KKK25493.1 - 5.3e-19 67.9 0.0 1.1e-18 66.8 0.0 1.6 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex Nup160 PF11715.3 KKK25493.1 - 0.0032 15.6 0.6 0.0032 15.6 0.4 2.1 2 1 0 3 3 3 1 Nucleoporin Nup120/160 Apc4_WD40 PF12894.2 KKK25493.1 - 0.071 12.6 0.0 1.3 8.5 0.0 2.9 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Fungal_trans PF04082.13 KKK25494.1 - 2.1e-22 79.2 0.1 3.2e-22 78.6 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK25494.1 - 3.1e-10 39.7 9.1 4.6e-10 39.2 6.3 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RTA1 PF04479.8 KKK25495.1 - 3.2e-37 128.2 8.6 5e-37 127.5 6.0 1.2 1 0 0 1 1 1 1 RTA1 like protein DUF3671 PF12420.3 KKK25495.1 - 0.0036 17.2 7.4 0.65 10.0 0.4 3.5 2 2 1 3 3 3 2 Protein of unknown function DUF1980 PF09323.5 KKK25495.1 - 0.24 11.1 7.4 1.1 9.0 0.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) DUF1385 PF07136.6 KKK25495.1 - 2.1 7.3 7.8 0.18 10.8 1.1 2.2 1 1 2 3 3 3 0 Protein of unknown function (DUF1385) DUF373 PF04123.8 KKK25495.1 - 3.7 6.4 8.3 0.86 8.5 2.7 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF373) ADH_zinc_N PF00107.21 KKK25496.1 - 9.7e-22 76.9 0.1 1.8e-21 76.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KKK25496.1 - 2.5e-16 60.7 0.0 5.1e-16 59.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KKK25496.1 - 5.2e-12 45.5 0.0 5.3e-11 42.2 0.0 2.2 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Aminotran_3 PF00202.16 KKK25496.1 - 0.026 13.4 0.0 0.03 13.1 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-III Aldo_ket_red PF00248.16 KKK25497.1 - 1.2e-44 152.2 0.0 1.6e-44 151.8 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family NAD_binding_10 PF13460.1 KKK25499.1 - 1.2e-16 61.2 0.1 1.5e-16 60.9 0.1 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KKK25499.1 - 6.1e-16 58.5 0.0 8.6e-16 58.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 KKK25499.1 - 9.8e-11 41.3 0.1 3.2e-10 39.6 0.0 1.8 2 0 0 2 2 2 1 NmrA-like family 3Beta_HSD PF01073.14 KKK25499.1 - 5.1e-10 38.5 0.0 2.1e-09 36.4 0.0 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 KKK25499.1 - 1.2e-06 27.6 0.5 0.00029 19.8 0.3 2.2 1 1 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.12 KKK25499.1 - 5e-06 25.6 0.0 7.1e-06 25.1 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Saccharop_dh PF03435.13 KKK25499.1 - 0.0007 18.6 0.0 0.001 18.1 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase adh_short PF00106.20 KKK25499.1 - 0.022 14.6 1.3 0.042 13.7 0.1 2.1 2 1 0 2 2 2 0 short chain dehydrogenase Semialdhyde_dh PF01118.19 KKK25499.1 - 0.16 12.3 0.5 5.5 7.3 0.1 2.4 1 1 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain ADH_N PF08240.7 KKK25500.1 - 2.7e-28 97.8 1.1 5.3e-28 96.9 0.2 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KKK25500.1 - 9.6e-22 76.9 0.0 2.8e-21 75.3 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.1 KKK25500.1 - 0.024 14.2 0.1 0.039 13.6 0.1 1.3 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-associated AlaDh_PNT_C PF01262.16 KKK25500.1 - 0.03 13.8 0.0 0.052 13.1 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.1 KKK25500.1 - 0.14 12.2 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NADH_4Fe-4S PF10589.4 KKK25500.1 - 2 7.6 6.0 18 4.5 4.6 2.2 2 1 0 2 2 2 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region Tannase PF07519.6 KKK25501.1 - 1.9e-82 277.4 0.0 2.6e-82 277.0 0.0 1.2 1 0 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_6 PF12697.2 KKK25501.1 - 0.00017 21.5 0.2 0.00058 19.8 0.1 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KKK25501.1 - 0.0013 18.3 0.0 0.0038 16.8 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KKK25501.1 - 0.0017 17.6 0.1 0.7 9.0 0.1 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KKK25501.1 - 0.0031 17.2 0.1 0.15 11.8 0.0 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family SET PF00856.23 KKK25502.1 - 0.016 15.4 0.0 0.025 14.8 0.0 1.2 1 0 0 1 1 1 0 SET domain p450 PF00067.17 KKK25503.1 - 1.5e-66 224.8 0.0 1.9e-66 224.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Med7 PF05983.6 KKK25504.1 - 2.6e-58 196.3 0.4 3.2e-58 196.1 0.3 1.1 1 0 0 1 1 1 1 MED7 protein MerR-DNA-bind PF09278.6 KKK25504.1 - 0.08 13.3 0.9 0.19 12.1 0.6 1.7 1 0 0 1 1 1 0 MerR, DNA binding PAP2 PF01569.16 KKK25505.1 - 3.8e-23 81.5 0.8 3.8e-23 81.5 0.5 2.3 2 1 0 2 2 2 1 PAP2 superfamily DUF368 PF04018.8 KKK25505.1 - 0.025 13.7 0.7 1 8.4 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF368) DUF3429 PF11911.3 KKK25505.1 - 0.23 11.4 4.4 2.4 8.1 1.5 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3429) DUF3975 PF13126.1 KKK25505.1 - 0.59 10.3 2.8 0.76 9.9 1.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3975) Virul_fac_BrkB PF03631.10 KKK25505.1 - 1.9 7.7 10.6 15 4.8 0.1 2.1 2 0 0 2 2 2 0 Virulence factor BrkB T5orf172 PF10544.4 KKK25506.1 - 1.4e-09 38.2 0.1 1.4e-08 34.9 0.0 2.4 1 1 0 1 1 1 1 T5orf172 domain MUG113 PF13455.1 KKK25506.1 - 6.2e-06 26.5 0.5 0.0015 18.9 0.1 3.0 2 1 0 2 2 2 1 Meiotically up-regulated gene 113 Patched PF02460.13 KKK25507.1 - 1.3e-77 261.4 14.1 3.5e-77 260.0 9.7 1.6 1 1 0 1 1 1 1 Patched family Sterol-sensing PF12349.3 KKK25507.1 - 7.6e-51 171.5 7.2 7.6e-51 171.5 5.0 2.9 3 0 0 3 3 3 1 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.10 KKK25507.1 - 1.3e-06 27.4 9.8 1.3e-06 27.4 6.8 3.5 3 1 0 3 3 3 2 MMPL family Pkinase PF00069.20 KKK25508.1 - 2e-68 230.3 0.0 2.6e-68 229.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK25508.1 - 9.4e-29 100.2 0.0 1.6e-28 99.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KKK25508.1 - 0.032 13.9 1.3 0.066 12.9 0.0 2.0 2 2 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 KKK25508.1 - 0.092 11.7 0.1 0.24 10.4 0.0 1.7 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family NeA_P2 PF12312.3 KKK25509.1 - 1.5 7.9 11.8 1.6 7.9 3.4 2.4 2 0 0 2 2 2 0 Nepovirus subgroup A polyprotein DUF1183 PF06682.7 KKK25509.1 - 7.2 6.1 7.7 0.36 10.3 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1183) COQ9 PF08511.6 KKK25510.1 - 3.7e-26 90.4 0.1 6.7e-26 89.6 0.0 1.4 1 0 0 1 1 1 1 COQ9 RRM_1 PF00076.17 KKK25511.1 - 1.3e-45 152.8 0.0 6.2e-17 60.9 0.0 3.8 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KKK25511.1 - 9.9e-39 131.1 0.0 1.5e-15 56.9 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KKK25511.1 - 3.6e-23 81.1 0.0 2.5e-07 30.4 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 KKK25511.1 - 0.0003 20.4 0.2 3.7 7.3 0.0 4.2 3 2 0 3 3 3 2 Limkain b1 ATP-grasp_2 PF08442.5 KKK25511.1 - 0.01 15.2 0.0 0.084 12.2 0.0 2.2 2 0 0 2 2 2 0 ATP-grasp domain RRM_3 PF08777.6 KKK25511.1 - 0.024 14.4 0.0 5.7 6.8 0.0 2.9 3 0 0 3 3 3 0 RNA binding motif PknH_C PF14032.1 KKK25511.1 - 0.035 13.6 0.6 31 4.0 0.0 3.2 3 0 0 3 3 3 0 PknH-like extracellular domain PH PF00169.24 KKK25512.1 - 2.8e-11 43.5 0.2 9.3e-11 41.8 0.1 2.0 1 0 0 1 1 1 1 PH domain Prominin PF05478.6 KKK25512.1 - 0.59 7.5 0.7 2.1 5.7 0.1 1.9 2 0 0 2 2 2 0 Prominin Tim17 PF02466.14 KKK25513.1 - 3.1e-15 56.3 8.7 4.5e-15 55.8 6.0 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family UCH PF00443.24 KKK25514.1 - 3.2e-48 164.1 0.0 2e-47 161.6 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RPT PF13446.1 KKK25514.1 - 1e-46 156.1 1.7 1.1e-22 79.1 0.1 4.5 4 0 0 4 4 4 4 A repeated domain in UCH-protein UCH_1 PF13423.1 KKK25514.1 - 1.1e-11 44.7 0.5 1.3e-06 28.0 0.0 2.7 3 0 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase E7 PF00527.13 KKK25514.1 - 0.026 14.6 0.0 0.13 12.4 0.0 2.2 1 0 0 1 1 1 0 E7 protein, Early protein PUB PF09409.5 KKK25514.1 - 0.16 11.7 0.0 1.8 8.3 0.0 2.4 2 0 0 2 2 2 0 PUB domain CoA_trans PF01144.18 KKK25515.1 - 8e-103 342.2 4.7 1.1e-60 204.5 0.6 2.0 2 0 0 2 2 2 2 Coenzyme A transferase DUF822 PF05687.8 KKK25516.1 - 1.7 8.9 6.3 2.3 8.5 4.4 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF822) DUF2370 PF10176.4 KKK25517.1 - 7.4e-89 297.1 0.0 1.5e-88 296.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2370) DUF2561 PF10812.3 KKK25517.1 - 0.12 11.9 0.0 0.29 10.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) WD40 PF00400.27 KKK25518.1 - 1.2e-15 56.6 0.5 0.00034 20.3 0.1 4.3 4 0 0 4 4 4 3 WD domain, G-beta repeat Terpene_synth_C PF03936.11 KKK25557.1 - 0.00044 19.5 0.2 0.0007 18.8 0.2 1.3 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain p450 PF00067.17 KKK25558.1 - 1.5e-52 178.7 0.0 2.1e-52 178.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Ribosomal_S18 PF01084.15 KKK25596.1 - 2.8e-15 55.9 0.1 5.1e-15 55.0 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S18 HTH_Tnp_Mu_1 PF02316.11 KKK25596.1 - 0.12 12.1 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 Mu DNA-binding domain SAGA-Tad1 PF12767.2 KKK25597.1 - 2.3e-64 217.4 0.0 5.5e-64 216.2 0.0 1.7 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit WD40 PF00400.27 KKK25597.1 - 8.4e-44 145.9 21.5 4e-08 32.8 0.1 11.4 11 0 0 11 11 11 7 WD domain, G-beta repeat FUSC_2 PF13515.1 KKK25597.1 - 8.8e-18 64.4 2.7 7.1e-12 45.3 0.9 3.7 2 2 1 3 3 3 2 Fusaric acid resistance protein-like ALMT PF11744.3 KKK25597.1 - 8.2e-08 31.3 3.5 0.002 16.8 0.0 3.6 3 0 0 3 3 3 3 Aluminium activated malate transporter FUSC PF04632.7 KKK25597.1 - 0.00035 19.1 18.2 0.0056 15.1 0.6 4.1 3 1 0 4 4 4 3 Fusaric acid resistance protein family DUF2422 PF10337.4 KKK25597.1 - 0.056 12.2 7.4 0.067 11.9 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2422) PRP1_N PF06424.7 KKK25598.1 - 8.9e-54 181.4 5.7 2.6e-53 179.9 4.0 1.9 1 0 0 1 1 1 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.1 KKK25598.1 - 3.8e-27 92.3 36.4 7.6e-05 23.0 0.2 14.1 5 3 10 15 15 15 9 Tetratricopeptide repeat TPR_19 PF14559.1 KKK25598.1 - 5.4e-24 84.3 14.2 3.8e-06 27.1 0.3 9.3 7 2 2 9 9 9 5 Tetratricopeptide repeat TPR_16 PF13432.1 KKK25598.1 - 3e-20 72.3 29.1 4.7e-05 23.9 1.9 8.7 8 1 2 10 10 9 4 Tetratricopeptide repeat TPR_11 PF13414.1 KKK25598.1 - 1.2e-12 47.2 9.7 0.00066 19.2 0.0 7.4 5 3 2 7 7 7 4 TPR repeat TPR_2 PF07719.12 KKK25598.1 - 1.1e-08 34.3 18.2 0.86 9.6 0.0 9.2 11 0 0 11 11 9 4 Tetratricopeptide repeat TPR_1 PF00515.23 KKK25598.1 - 1.3e-06 27.7 1.8 0.27 10.9 0.0 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.1 KKK25598.1 - 1.5e-05 24.7 7.6 6.9 7.1 0.0 8.0 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_8 PF13181.1 KKK25598.1 - 3.2e-05 23.4 0.0 1.9 8.4 0.0 6.3 6 1 1 7 7 7 1 Tetratricopeptide repeat TPR_12 PF13424.1 KKK25598.1 - 0.0002 21.2 5.8 2 8.4 0.0 5.9 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.1 KKK25598.1 - 0.017 14.8 4.5 74 3.5 0.0 6.0 6 0 0 6 6 5 0 Tetratricopeptide repeat DUF3808 PF10300.4 KKK25598.1 - 0.11 11.0 0.3 7.5 4.9 0.0 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF3808) TPR_21 PF09976.4 KKK25598.1 - 2.2 8.2 22.0 0.55 10.1 1.4 4.8 3 1 1 5 5 5 0 Tetratricopeptide repeat RabGAP-TBC PF00566.13 KKK25599.1 - 2.5e-49 167.6 0.0 4.5e-49 166.8 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain RRM_1 PF00076.17 KKK25600.1 - 1.5e-37 127.0 0.2 1.8e-17 62.7 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KKK25600.1 - 3.7e-29 100.4 0.1 2e-13 50.1 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KKK25600.1 - 1.2e-14 53.8 0.1 2.7e-06 27.1 0.0 2.9 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KKK25600.1 - 0.0045 16.8 0.0 2.1 8.2 0.0 2.6 2 0 0 2 2 2 2 RNA binding motif MCRS_N PF13325.1 KKK25600.1 - 1.3 8.5 4.1 1.3 8.5 1.7 1.8 1 1 0 1 1 1 0 N-terminal region of micro-spherule protein Med15 PF09606.5 KKK25600.1 - 3.2 5.8 70.2 5.4 5.0 48.6 1.3 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal ELFV_dehydrog PF00208.16 KKK25601.1 - 3.4e-61 206.9 0.0 6.6e-61 205.9 0.0 1.5 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.7 KKK25601.1 - 1.8e-19 68.8 0.0 1.1e-14 52.9 0.0 2.1 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.13 KKK25601.1 - 0.0018 17.8 0.0 0.0062 16.1 0.0 1.8 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain PPR_3 PF13812.1 KKK25602.1 - 2.5e-13 49.1 4.4 0.015 15.5 0.0 8.1 10 0 0 10 10 10 3 Pentatricopeptide repeat domain PPR_2 PF13041.1 KKK25602.1 - 5e-06 26.3 0.6 0.71 9.8 0.0 5.0 5 1 1 6 6 6 2 PPR repeat family TPR_14 PF13428.1 KKK25602.1 - 0.00012 22.4 1.2 35 5.4 0.0 5.9 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_19 PF14559.1 KKK25602.1 - 0.0014 18.8 1.2 0.59 10.5 0.4 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat PPR PF01535.15 KKK25602.1 - 0.014 15.2 7.0 1.1 9.4 0.0 5.7 7 0 0 7 7 7 0 PPR repeat UQ_con PF00179.21 KKK25614.1 - 2.4e-28 98.2 0.1 9.9e-15 54.2 0.0 3.1 2 1 0 2 2 2 2 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KKK25614.1 - 0.00043 20.0 0.1 1.6 8.4 0.0 3.2 2 1 0 2 2 2 2 Prokaryotic E2 family B RhoGAP PF00620.22 KKK25615.1 - 6.5e-37 126.4 0.5 1.3e-36 125.4 0.4 1.5 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.17 KKK25615.1 - 2.1e-29 101.3 34.6 4.5e-12 45.8 4.0 4.8 5 0 0 5 5 5 4 LIM domain Desulfoferrod_N PF06397.7 KKK25615.1 - 4.1 6.8 7.6 0.11 11.9 0.3 2.2 3 0 0 3 3 3 0 Desulfoferrodoxin, N-terminal domain DUF164 PF02591.10 KKK25615.1 - 5.7 6.8 11.0 4 7.3 0.1 3.7 3 0 0 3 3 3 0 Putative zinc ribbon domain 3Beta_HSD PF01073.14 KKK25616.1 - 6.9e-43 146.3 0.7 1.9e-23 82.5 0.0 3.0 2 1 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 KKK25616.1 - 1.3e-18 67.3 0.0 8.4e-12 45.0 0.0 2.6 2 1 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 KKK25616.1 - 2e-09 36.7 0.0 2.5e-08 33.1 0.0 2.4 2 1 0 2 2 2 1 Male sterility protein RmlD_sub_bind PF04321.12 KKK25616.1 - 6.6e-06 25.2 0.0 0.0092 14.8 0.0 2.9 3 0 0 3 3 3 2 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 KKK25616.1 - 0.013 14.4 0.0 0.14 11.0 0.0 2.0 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein KR PF08659.5 KKK25616.1 - 0.048 13.3 0.0 0.19 11.3 0.0 2.0 1 1 0 1 1 1 0 KR domain NAD_binding_10 PF13460.1 KKK25616.1 - 0.12 12.4 0.0 5 7.0 0.0 2.6 3 0 0 3 3 3 0 NADH(P)-binding Pkinase PF00069.20 KKK25617.1 - 8.2e-60 202.1 0.0 1.2e-38 132.7 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KKK25617.1 - 5.9e-26 91.0 0.0 2.8e-20 72.4 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.19 KKK25617.1 - 2.2e-11 43.7 0.2 6.2e-11 42.2 0.0 1.8 2 0 0 2 2 2 1 Response regulator receiver domain Kinase-like PF14531.1 KKK25617.1 - 5.8e-08 32.0 0.4 1.5e-05 24.0 0.0 2.9 3 0 0 3 3 3 2 Kinase-like APH PF01636.18 KKK25617.1 - 2.6e-06 27.3 0.0 0.0045 16.7 0.1 2.8 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 KKK25617.1 - 0.004 16.2 0.0 0.0077 15.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PAS PF00989.19 KKK25617.1 - 0.008 15.9 0.0 0.022 14.5 0.0 1.8 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.1 KKK25617.1 - 0.011 16.0 0.0 0.028 14.7 0.0 1.7 1 0 0 1 1 1 0 PAS domain PAS_4 PF08448.5 KKK25617.1 - 0.053 13.5 0.0 0.18 11.8 0.0 1.9 1 0 0 1 1 1 0 PAS fold Seadorna_VP7 PF07387.6 KKK25617.1 - 0.054 12.3 0.1 0.15 10.8 0.0 1.7 2 0 0 2 2 2 0 Seadornavirus VP7 Macoilin PF09726.4 KKK25617.1 - 0.41 8.8 2.5 0.76 7.9 1.7 1.4 1 0 0 1 1 1 0 Transmembrane protein Malic_M PF03949.10 KKK25625.1 - 7.1e-80 268.2 0.0 1.2e-79 267.5 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 KKK25625.1 - 3e-64 215.9 0.2 6.9e-64 214.7 0.0 1.7 2 0 0 2 2 2 1 Malic enzyme, N-terminal domain Esterase PF00756.15 KKK25626.1 - 5.3e-10 39.1 0.0 2.1e-09 37.2 0.0 1.7 1 1 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.16 KKK25626.1 - 0.00083 18.6 0.0 0.0014 17.9 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 KKK25626.1 - 0.002 18.0 0.1 0.0028 17.5 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family PRANC PF09372.5 KKK25627.1 - 0.12 12.3 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 PRANC domain MFS_1 PF07690.11 KKK25629.1 - 4.5e-16 58.5 44.4 1.5e-09 37.0 20.1 2.5 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KKK25629.1 - 3.4e-06 25.9 14.9 6.9e-05 21.6 1.6 2.6 2 0 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.8 KKK25629.1 - 0.012 13.8 16.2 0.02 13.1 0.1 3.9 2 1 1 3 3 3 0 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 KKK25630.1 - 2e-10 39.9 45.6 4.6e-06 25.5 22.0 3.8 2 1 1 3 3 3 2 Major Facilitator Superfamily Mtp PF03821.11 KKK25630.1 - 0.093 12.1 0.1 0.21 10.9 0.1 1.6 1 0 0 1 1 1 0 Golgi 4-transmembrane spanning transporter Cytomega_TRL10 PF06084.6 KKK25630.1 - 0.22 11.2 3.7 0.46 10.2 0.6 2.4 2 0 0 2 2 2 0 Cytomegalovirus TRL10 protein SnoaL_2 PF12680.2 KKK25631.1 - 7.4e-10 39.1 0.8 9.4e-10 38.8 0.5 1.1 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_4 PF13577.1 KKK25631.1 - 8.9e-10 38.5 0.3 9.7e-10 38.4 0.2 1.1 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_3 PF13474.1 KKK25631.1 - 2.5e-07 30.7 0.2 3.2e-07 30.4 0.2 1.1 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.1 KKK25631.1 - 2.7e-06 27.5 0.3 3.5e-06 27.1 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) NTF2 PF02136.15 KKK25631.1 - 0.0004 20.7 0.1 0.00053 20.3 0.1 1.2 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain LEH PF07858.7 KKK25631.1 - 0.0011 18.9 0.1 0.0013 18.6 0.1 1.1 1 0 0 1 1 1 1 Limonene-1,2-epoxide hydrolase catalytic domain GldM_C PF12080.3 KKK25631.1 - 0.047 13.6 0.1 0.071 13.0 0.0 1.3 1 1 0 1 1 1 0 GldM C-terminal domain ZipA_C PF04354.8 KKK25631.1 - 0.077 12.4 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 ZipA, C-terminal FtsZ-binding domain E1-E2_ATPase PF00122.15 KKK25632.1 - 1.1e-52 178.3 2.1 2.1e-52 177.4 1.4 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KKK25632.1 - 8.1e-38 129.7 2.9 8.1e-38 129.7 2.0 2.7 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KKK25632.1 - 2.8e-31 109.6 0.0 2.2e-30 106.7 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KKK25632.1 - 1e-19 70.2 0.0 1.9e-19 69.3 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 KKK25632.1 - 5.7e-16 59.2 0.0 1.8e-15 57.6 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KKK25632.1 - 7.6e-12 44.5 0.0 2.2e-11 43.0 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 KKK25632.1 - 4.3e-05 23.2 0.2 8.1e-05 22.3 0.2 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF1625 PF07787.7 KKK25632.1 - 0.056 12.6 1.2 2.5 7.2 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1625) DUF2207 PF09972.4 KKK25632.1 - 3.8 5.9 3.6 4 5.9 0.0 2.3 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) MFS_1 PF07690.11 KKK25633.1 - 2.9e-40 138.0 33.9 4.2e-40 137.5 23.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KKK25633.1 - 1.1e-14 53.9 6.3 1.1e-14 53.9 4.4 1.7 2 0 0 2 2 2 1 Sugar (and other) transporter Zn_clus PF00172.13 KKK25633.1 - 3.2e-06 26.9 10.6 6.8e-06 25.9 7.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_3 PF05977.8 KKK25633.1 - 0.0015 16.7 0.5 0.0025 16.0 0.4 1.2 1 0 0 1 1 1 1 Transmembrane secretion effector MARVEL PF01284.18 KKK25646.1 - 4.4e-19 68.7 12.8 5.3e-19 68.4 8.9 1.1 1 0 0 1 1 1 1 Membrane-associating domain DUF2615 PF11027.3 KKK25646.1 - 0.0037 17.1 0.0 0.0067 16.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2615) DUF872 PF05915.7 KKK25646.1 - 0.12 12.1 0.2 9.9 6.0 0.0 2.2 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) CTP_transf_1 PF01148.15 KKK25646.1 - 0.19 11.3 6.7 0.24 11.0 4.7 1.2 1 0 0 1 1 1 0 Cytidylyltransferase family ATP-synt_8 PF00895.15 KKK25646.1 - 1.1 9.4 3.8 3.3 7.9 0.1 3.0 3 0 0 3 3 3 0 ATP synthase protein 8 DUF2427 PF10348.4 KKK25646.1 - 4.5 6.8 7.9 3.7 7.1 3.3 2.3 1 1 2 3 3 3 0 Domain of unknown function (DUF2427) Actin PF00022.14 KKK25647.1 - 1.1e-52 178.8 0.0 3.2e-29 101.5 0.0 2.2 2 0 0 2 2 2 2 Actin Phage_connect_1 PF05135.8 KKK25647.1 - 0.062 13.4 0.4 0.18 12.0 0.3 1.8 1 0 0 1 1 1 0 Phage gp6-like head-tail connector protein DASH_Dad4 PF08650.5 KKK25648.1 - 5.3e-27 93.5 6.7 6.8e-27 93.1 4.6 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad4 DASH_Dad1 PF08649.5 KKK25648.1 - 0.01 15.4 2.7 0.014 15.0 1.9 1.2 1 0 0 1 1 1 0 DASH complex subunit Dad1 Kdo PF06293.9 KKK25648.1 - 0.051 12.6 0.1 0.059 12.4 0.1 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family GM_CSF PF01109.12 KKK25648.1 - 0.059 13.3 0.4 0.076 12.9 0.2 1.2 1 0 0 1 1 1 0 Granulocyte-macrophage colony-stimulating factor MitMem_reg PF13012.1 KKK25648.1 - 0.064 13.3 3.1 0.095 12.7 2.1 1.4 1 1 0 1 1 1 0 Maintenance of mitochondrial structure and function YL1_C PF08265.6 KKK25649.1 - 6.1e-16 57.6 0.2 1e-15 56.9 0.1 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain Got1 PF04178.7 KKK25650.1 - 1.1e-19 70.6 13.6 1.3e-19 70.4 9.4 1.0 1 0 0 1 1 1 1 Got1/Sft2-like family YrhK PF14145.1 KKK25650.1 - 0.8 9.4 9.3 0.19 11.4 3.7 1.9 2 0 0 2 2 2 0 YrhK-like protein DUF3040 PF11239.3 KKK25650.1 - 1.5 8.8 4.9 0.53 10.3 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3040) DUF2157 PF09925.4 KKK25650.1 - 2.8 7.5 7.8 5 6.7 5.4 1.5 1 1 0 1 1 1 0 Predicted membrane protein (DUF2157) Profilin PF00235.14 KKK25651.1 - 3.4e-37 127.2 0.2 3.9e-37 127.0 0.1 1.0 1 0 0 1 1 1 1 Profilin Nucleo_P87 PF07267.6 KKK25652.1 - 1.1 7.8 6.1 1.7 7.2 4.2 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Sec63 PF02889.11 KKK25653.1 - 2.5e-151 503.2 0.0 2.3e-96 322.7 0.0 2.2 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 KKK25653.1 - 2e-53 180.3 1.2 1.5e-27 96.1 0.6 3.9 5 0 0 5 5 5 2 DEAD/DEAH box helicase Helicase_C PF00271.26 KKK25653.1 - 1.4e-17 63.3 0.0 2.2e-07 30.6 0.0 3.0 3 0 0 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.10 KKK25653.1 - 2.3e-16 60.1 0.0 7.1e-07 29.2 0.0 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit AAA_22 PF13401.1 KKK25653.1 - 8.6e-08 32.3 0.1 0.0051 16.9 0.0 3.3 2 1 0 2 2 2 2 AAA domain AAA_19 PF13245.1 KKK25653.1 - 3e-05 23.6 0.2 0.027 14.1 0.0 2.9 2 0 0 2 2 2 2 Part of AAA domain SNF2_N PF00176.18 KKK25653.1 - 0.00011 21.1 0.4 0.22 10.2 0.0 2.3 2 0 0 2 2 2 2 SNF2 family N-terminal domain FtsK_SpoIIIE PF01580.13 KKK25653.1 - 0.0074 15.7 0.1 0.9 8.9 0.1 2.9 2 0 0 2 2 2 1 FtsK/SpoIIIE family Zeta_toxin PF06414.7 KKK25653.1 - 0.014 14.5 0.2 10 5.1 0.0 3.7 4 0 0 4 4 4 0 Zeta toxin IstB_IS21 PF01695.12 KKK25653.1 - 0.02 14.2 0.7 7.6 5.9 0.0 3.8 4 0 0 4 4 4 0 IstB-like ATP binding protein AAA_10 PF12846.2 KKK25653.1 - 0.042 13.2 0.0 10 5.4 0.0 3.4 3 1 0 4 4 4 0 AAA-like domain PhoH PF02562.11 KKK25653.1 - 0.046 12.9 0.0 7.3 5.7 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein DUF3431 PF11913.3 KKK25654.1 - 2.5e-91 305.1 1.1 3e-91 304.8 0.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) Ras PF00071.17 KKK25655.1 - 1.6e-39 134.9 0.0 1.6e-38 131.6 0.0 1.9 1 1 0 1 1 1 1 Ras family Miro PF08477.8 KKK25655.1 - 5.3e-17 62.4 0.0 8.5e-17 61.7 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KKK25655.1 - 2.9e-11 42.9 0.0 4.8e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KKK25655.1 - 0.0016 17.6 0.0 0.0022 17.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KKK25655.1 - 0.0018 18.2 0.0 0.0027 17.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 KKK25655.1 - 0.0023 18.0 0.0 0.0052 16.9 0.0 1.6 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.1 KKK25655.1 - 0.0027 17.6 0.0 0.011 15.7 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain SRPRB PF09439.5 KKK25655.1 - 0.0082 15.3 0.0 0.012 14.7 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 KKK25655.1 - 0.0099 15.3 0.0 0.087 12.3 0.0 2.1 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.12 KKK25655.1 - 0.035 13.6 0.2 6.1 6.2 0.1 2.7 2 1 1 3 3 3 0 Conserved hypothetical ATP binding protein AAA_28 PF13521.1 KKK25655.1 - 0.041 13.8 0.0 0.072 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 KKK25655.1 - 0.046 12.9 0.0 0.075 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_14 PF13173.1 KKK25655.1 - 0.057 13.3 0.0 0.087 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 KKK25655.1 - 0.09 12.3 0.1 0.15 11.5 0.1 1.3 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 KKK25655.1 - 0.099 12.3 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase ATP-synt_ab PF00006.20 KKK25655.1 - 0.11 12.0 0.0 0.12 11.8 0.0 1.1 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_33 PF13671.1 KKK25655.1 - 0.12 12.2 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 KKK25655.1 - 0.13 11.9 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NACHT PF05729.7 KKK25655.1 - 0.13 11.8 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 NACHT domain Metallophos PF00149.23 KKK25656.1 - 1.2e-06 28.0 3.4 0.00013 21.3 0.1 2.6 2 1 0 2 2 2 2 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KKK25656.1 - 1.5e-05 24.8 0.0 3.5e-05 23.6 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Sugar_tr PF00083.19 KKK25657.1 - 1.5e-104 350.0 24.1 1.8e-104 349.8 16.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KKK25657.1 - 7.4e-26 90.6 35.6 1.2e-17 63.7 6.0 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KKK25657.1 - 0.00091 17.7 2.4 0.00091 17.7 1.7 3.6 3 1 0 3 3 3 2 MFS/sugar transport protein MFS_3 PF05977.8 KKK25657.1 - 0.018 13.1 0.1 0.018 13.1 0.1 2.1 2 1 1 3 3 3 0 Transmembrane secretion effector IlvC PF01450.14 KKK25657.1 - 0.16 11.8 0.2 1.3 8.9 0.0 2.3 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain ADH_N PF08240.7 KKK25659.1 - 1.1e-21 76.6 2.1 1.1e-21 76.6 1.5 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_N_assoc PF13823.1 KKK25659.1 - 0.016 14.8 0.0 0.029 14.0 0.0 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-associated ADH_zinc_N PF00107.21 KKK25659.1 - 0.062 12.8 0.0 3.2 7.2 0.0 2.6 2 0 0 2 2 2 0 Zinc-binding dehydrogenase Abhydrolase_6 PF12697.2 KKK25660.1 - 2.8e-21 76.4 0.0 3.3e-21 76.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KKK25660.1 - 9.4e-18 64.6 0.0 2.8e-17 63.0 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KKK25660.1 - 2.5e-07 30.5 0.0 1.3e-06 28.2 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.9 KKK25660.1 - 5.4e-05 21.8 0.0 0.00013 20.5 0.0 1.6 1 1 0 1 1 1 1 Ndr family Ribonuclease_3 PF00636.21 KKK25661.1 - 7.9e-05 23.0 0.0 0.00026 21.4 0.0 1.8 1 1 0 1 1 1 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 KKK25661.1 - 0.0032 17.4 0.0 0.0045 16.9 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease-III-like 2OG-FeII_Oxy PF03171.15 KKK25664.1 - 2.6e-15 56.5 0.0 4.8e-15 55.6 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 KKK25664.1 - 8.1e-12 45.6 0.0 2.3e-11 44.2 0.0 1.8 1 1 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal AflR PF08493.5 KKK25665.1 - 3.6e-20 72.1 13.1 4.7e-20 71.7 9.1 1.2 1 0 0 1 1 1 1 Aflatoxin regulatory protein Zn_clus PF00172.13 KKK25665.1 - 3.2e-09 36.5 11.1 5.4e-09 35.8 7.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fer4_6 PF12837.2 KKK25665.1 - 6.6 6.7 8.0 18 5.4 0.2 3.0 3 0 0 3 3 3 0 4Fe-4S binding domain 2OG-FeII_Oxy_2 PF13532.1 KKK25666.1 - 1.1e-32 113.5 0.1 1.5e-32 113.0 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily zf-GRF PF06839.7 KKK25666.1 - 1e-06 28.5 5.8 1.8e-06 27.7 4.0 1.4 1 0 0 1 1 1 1 GRF zinc finger DinI PF06183.8 KKK25666.1 - 0.089 12.8 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 DinI-like family 2OG-FeII_Oxy PF03171.15 KKK25666.1 - 0.11 12.7 0.0 0.23 11.8 0.0 1.5 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily DUF3425 PF11905.3 KKK25667.1 - 1.2e-27 96.4 1.7 2.1e-27 95.6 1.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) NPV_P10 PF05531.7 KKK25667.1 - 0.0031 17.7 1.1 0.006 16.8 0.8 1.4 1 0 0 1 1 1 1 Nucleopolyhedrovirus P10 protein GP41 PF00517.12 KKK25667.1 - 0.022 14.3 2.1 0.038 13.5 1.5 1.3 1 0 0 1 1 1 0 Retroviral envelope protein SlyX PF04102.7 KKK25667.1 - 0.029 14.7 3.5 0.063 13.6 2.4 1.6 1 0 0 1 1 1 0 SlyX V_ATPase_I PF01496.14 KKK25667.1 - 0.064 11.1 1.4 0.084 10.7 1.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Herpes_UL6 PF01763.11 KKK25667.1 - 0.066 11.3 2.6 0.09 10.9 1.8 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like Atg14 PF10186.4 KKK25667.1 - 0.11 11.3 5.7 0.16 10.9 3.9 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Fmp27_WPPW PF10359.4 KKK25667.1 - 0.13 10.6 3.9 0.18 10.1 2.7 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DUF572 PF04502.8 KKK25667.1 - 0.23 10.6 5.9 0.32 10.1 4.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Prominin PF05478.6 KKK25667.1 - 0.27 8.7 2.1 0.36 8.3 1.4 1.1 1 0 0 1 1 1 0 Prominin MbeD_MobD PF04899.7 KKK25667.1 - 0.4 10.6 5.7 0.5 10.2 2.6 2.1 2 0 0 2 2 2 0 MbeD/MobD like Spc7 PF08317.6 KKK25667.1 - 1.1 7.8 7.0 1.7 7.1 4.8 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Phlebovirus_NSM PF07246.6 KKK25667.1 - 1.7 7.7 5.7 2.4 7.2 3.9 1.1 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M ADIP PF11559.3 KKK25667.1 - 2 8.2 13.8 3.2 7.6 9.5 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding IncA PF04156.9 KKK25667.1 - 2.3 7.7 6.5 3.6 7.1 4.5 1.2 1 0 0 1 1 1 0 IncA protein Macoilin PF09726.4 KKK25667.1 - 2.7 6.1 7.1 3.6 5.7 4.9 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF16 PF01519.11 KKK25667.1 - 5.3 7.3 8.1 8.2 6.7 5.6 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF16 Fringe PF02434.11 KKK25668.1 - 4.4e-10 39.2 0.1 6.7e-09 35.3 0.1 2.2 1 1 0 1 1 1 1 Fringe-like PAN_1 PF00024.21 KKK25668.1 - 0.0033 17.1 0.4 0.0059 16.3 0.3 1.4 1 0 0 1 1 1 1 PAN domain PAN_2 PF08276.6 KKK25668.1 - 0.0071 16.1 0.5 0.015 15.1 0.3 1.4 1 0 0 1 1 1 1 PAN-like domain PAN_4 PF14295.1 KKK25668.1 - 0.0077 15.9 0.4 0.025 14.2 0.3 1.8 1 0 0 1 1 1 1 PAN domain Glyco_transf_34 PF05637.7 KKK25668.1 - 0.53 9.7 2.8 0.93 8.9 2.0 1.3 1 0 0 1 1 1 0 galactosyl transferase GMA12/MNN10 family M20_dimer PF07687.9 KKK25669.1 - 6.7e-09 35.4 0.2 1.7e-08 34.1 0.0 1.7 2 0 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M20 PF01546.23 KKK25669.1 - 7e-09 35.4 0.4 1e-08 34.8 0.2 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Lzipper-MIP1 PF14389.1 KKK25669.1 - 0.14 12.3 0.1 0.27 11.3 0.1 1.4 1 0 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 PhyH PF05721.8 KKK25670.1 - 8.8e-12 45.5 0.0 1.4e-11 44.8 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.7 KKK25670.1 - 8.2e-09 34.4 0.1 0.017 13.6 0.0 3.1 3 0 0 3 3 3 3 Protein of unknown function (DUF1479) MFS_1 PF07690.11 KKK25671.1 - 3.9e-29 101.4 36.6 3.9e-29 101.4 25.4 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily ESSS PF10183.4 KKK25671.1 - 1.9 8.9 5.4 0.35 11.3 0.2 2.4 2 0 0 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) bZIP_1 PF00170.16 KKK25672.1 - 1.2e-09 37.9 15.5 2.1e-09 37.1 10.8 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KKK25672.1 - 1.2e-06 28.2 13.9 2.4e-06 27.2 9.6 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 KKK25672.1 - 0.014 15.7 10.7 0.026 14.8 7.4 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor SOBP PF15279.1 KKK25672.1 - 0.033 14.5 6.7 0.043 14.1 4.7 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein IFT57 PF10498.4 KKK25672.1 - 0.073 11.7 4.9 0.11 11.2 3.4 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 DivIC PF04977.10 KKK25672.1 - 0.13 11.7 4.4 0.28 10.6 3.1 1.5 1 0 0 1 1 1 0 Septum formation initiator DUF342 PF03961.8 KKK25672.1 - 0.3 9.4 3.2 0.4 9.0 2.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Hemerythrin PF01814.18 KKK25673.1 - 8.8e-05 22.6 0.1 0.001 19.2 0.0 2.3 1 1 0 1 1 1 1 Hemerythrin HHE cation binding domain CppA_C PF14507.1 KKK25673.1 - 0.12 12.5 0.0 0.41 10.8 0.0 1.9 2 1 0 2 2 2 0 CppA C-terminal DUF3328 PF11807.3 KKK25674.1 - 7.5e-58 195.7 0.5 9e-58 195.4 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF4188 PF13826.1 KKK25675.1 - 6.1e-31 106.9 0.3 8.2e-31 106.5 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4188) Dabb PF07876.7 KKK25675.1 - 0.00029 21.2 0.0 0.00047 20.5 0.0 1.2 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain HSP70 PF00012.15 KKK25676.1 - 1e-78 264.8 0.0 2.9e-78 263.3 0.0 1.6 1 1 0 1 1 1 1 Hsp70 protein Arginase PF00491.16 KKK25678.1 - 5.4e-09 35.7 0.0 6.2e-09 35.5 0.0 1.1 1 0 0 1 1 1 1 Arginase family MFS_1 PF07690.11 KKK25679.1 - 4.1e-29 101.4 19.8 4.1e-29 101.4 13.7 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF4231 PF14015.1 KKK25679.1 - 0.035 14.1 0.4 0.78 9.7 0.0 3.0 4 0 0 4 4 4 0 Protein of unknown function (DUF4231) PAP_assoc PF03828.14 KKK25683.1 - 2.2e-17 62.7 0.1 4.9e-17 61.6 0.0 1.6 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 KKK25683.1 - 3.4e-06 27.3 0.0 6.3e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain Ras PF00071.17 KKK25700.1 - 1.5e-53 180.4 0.0 1.7e-53 180.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KKK25700.1 - 6.4e-16 58.9 0.0 9.9e-16 58.3 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KKK25700.1 - 1.1e-06 28.0 0.0 1.4e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KKK25700.1 - 0.0016 17.8 0.0 0.0077 15.6 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 KKK25700.1 - 0.004 16.3 0.0 0.0056 15.9 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 KKK25700.1 - 0.0056 15.8 0.0 0.0067 15.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region NB-ARC PF00931.17 KKK25700.1 - 0.018 13.8 0.0 0.14 10.9 0.0 1.9 2 0 0 2 2 2 0 NB-ARC domain Selenoprotein_S PF06936.6 KKK25703.1 - 0.89 9.0 7.9 0.053 13.0 0.5 2.4 2 0 0 2 2 2 0 Selenoprotein S (SelS) Myosin_head PF00063.16 KKK25704.1 - 4.1e-254 844.7 0.3 1.3e-253 843.1 0.2 1.9 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_tail_1 PF01576.14 KKK25704.1 - 1.2e-22 79.5 302.6 5e-19 67.5 95.0 6.0 1 1 2 3 3 3 2 Myosin tail Myosin_N PF02736.14 KKK25704.1 - 0.00024 20.6 0.0 0.00074 19.1 0.0 1.8 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain AAA_19 PF13245.1 KKK25704.1 - 0.084 12.6 0.0 0.29 10.9 0.0 2.0 1 0 0 1 1 1 0 Part of AAA domain zf-C3H1 PF10650.4 KKK25705.1 - 1.2e-11 43.8 2.7 1.9e-11 43.2 1.9 1.3 1 0 0 1 1 1 1 Putative zinc-finger domain APG6 PF04111.7 KKK25705.1 - 3.4 6.6 12.9 0.13 11.2 1.7 2.5 2 0 0 2 2 2 0 Autophagy protein Apg6 zf-DHHC PF01529.15 KKK25706.1 - 9.1e-06 25.1 3.6 1.3e-05 24.6 2.5 1.2 1 0 0 1 1 1 1 DHHC palmitoyltransferase MpPF26 PF07666.6 KKK25706.1 - 0.37 10.6 2.9 0.57 10.0 2.0 1.2 1 0 0 1 1 1 0 M penetrans paralogue family 26 COX4_pro_2 PF07835.7 KKK25706.1 - 0.94 9.5 6.0 1.8 8.6 4.2 1.4 1 0 0 1 1 1 0 Bacterial aa3 type cytochrome c oxidase subunit IV Sugar_tr PF00083.19 KKK25723.1 - 4.2e-75 253.0 16.2 5.1e-75 252.7 11.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KKK25723.1 - 8.6e-17 60.8 25.4 8.6e-17 60.8 17.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.13 KKK25724.1 - 9.8e-09 34.4 2.3 1.7e-08 33.6 0.2 2.2 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK25724.1 - 1.3e-08 34.6 13.3 2.5e-08 33.7 9.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ABC2_membrane PF01061.19 KKK25725.1 - 1.8e-86 288.6 51.0 2.6e-47 160.7 13.5 2.6 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 KKK25725.1 - 2.1e-40 138.2 0.0 4e-19 69.2 0.0 2.8 3 0 0 3 3 2 2 ABC transporter PDR_CDR PF06422.7 KKK25725.1 - 5.6e-23 80.5 0.1 5.6e-23 80.5 0.0 3.4 4 0 0 4 4 2 1 CDR ABC transporter ABC2_membrane_3 PF12698.2 KKK25725.1 - 1.3e-10 40.8 35.4 3.5e-08 32.8 12.3 2.6 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_16 PF13191.1 KKK25725.1 - 2.7e-07 30.7 0.1 5.1e-05 23.3 0.1 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.1 KKK25725.1 - 1.7e-05 24.9 0.0 1.1 9.1 0.0 3.3 2 1 0 3 3 3 2 AAA domain AAA_22 PF13401.1 KKK25725.1 - 6.3e-05 23.1 0.0 0.012 15.7 0.0 2.9 3 1 0 3 3 2 1 AAA domain UPF0079 PF02367.12 KKK25725.1 - 0.00029 20.4 0.1 0.065 12.8 0.1 2.3 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_18 PF13238.1 KKK25725.1 - 0.00052 20.3 0.0 0.023 14.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 KKK25725.1 - 0.00065 19.1 0.0 0.1 12.0 0.0 2.8 3 0 0 3 3 2 1 AAA domain DUF258 PF03193.11 KKK25725.1 - 0.0021 17.2 0.0 0.013 14.6 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 KKK25725.1 - 0.0044 16.5 0.1 0.052 13.0 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_33 PF13671.1 KKK25725.1 - 0.0047 16.8 0.0 0.068 13.0 0.0 2.8 3 0 0 3 3 3 1 AAA domain SMC_N PF02463.14 KKK25725.1 - 0.0047 16.1 0.0 2.5 7.2 0.0 3.0 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 KKK25725.1 - 0.0075 17.0 0.0 0.061 14.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 KKK25725.1 - 0.0088 15.5 0.0 0.11 11.8 0.0 2.2 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_28 PF13521.1 KKK25725.1 - 0.0095 15.9 0.1 0.037 13.9 0.1 2.0 2 0 0 2 2 1 1 AAA domain Arch_ATPase PF01637.13 KKK25725.1 - 0.014 15.1 0.0 3.7 7.1 0.0 2.4 2 0 0 2 2 2 0 Archaeal ATPase AAA_19 PF13245.1 KKK25725.1 - 0.016 14.9 0.0 1.3 8.8 0.0 2.6 2 0 0 2 2 2 0 Part of AAA domain cobW PF02492.14 KKK25725.1 - 0.021 14.2 0.0 0.18 11.2 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.7 KKK25725.1 - 0.031 13.9 0.4 1.6 8.3 0.1 3.1 3 0 0 3 3 3 0 NACHT domain SbcCD_C PF13558.1 KKK25725.1 - 0.04 13.8 0.0 0.18 11.7 0.0 2.1 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit ArgK PF03308.11 KKK25725.1 - 0.068 11.9 0.0 0.17 10.6 0.0 1.5 1 0 0 1 1 1 0 ArgK protein Miro PF08477.8 KKK25725.1 - 0.07 13.6 0.0 6.2 7.3 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein MMR_HSR1 PF01926.18 KKK25725.1 - 0.091 12.7 0.0 14 5.6 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase DUF4646 PF15496.1 KKK25726.1 - 3.9e-18 65.6 0.0 7.4e-18 64.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4646) DUF1049 PF06305.6 KKK25726.1 - 0.053 13.0 0.0 0.098 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) DUF1191 PF06697.7 KKK25726.1 - 0.11 11.3 0.2 0.15 10.8 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) Response_reg PF00072.19 KKK25727.1 - 2.2e-21 75.9 0.3 4.9e-21 74.8 0.1 1.8 2 0 0 2 2 2 1 Response regulator receiver domain HATPase_c PF02518.21 KKK25727.1 - 2.9e-18 65.5 0.1 5.5e-18 64.7 0.1 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 KKK25727.1 - 2.1e-13 50.0 0.2 5.4e-13 48.7 0.2 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF_3 PF13492.1 KKK25727.1 - 0.00035 20.6 0.0 0.38 10.8 0.0 2.8 3 0 0 3 3 3 2 GAF domain Phosphodiest PF01663.17 KKK25729.1 - 6.4e-14 52.0 0.3 1.3e-13 51.0 0.2 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.13 KKK25729.1 - 2.3e-06 27.2 0.3 3.9e-06 26.4 0.2 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.18 KKK25729.1 - 0.00017 20.8 0.1 0.0003 20.0 0.0 1.4 1 0 0 1 1 1 1 Sulfatase Gly-zipper_YMGG PF13441.1 KKK25729.1 - 0.25 10.9 4.2 0.55 9.7 2.9 1.5 1 0 0 1 1 1 0 YMGG-like Gly-zipper Podoplanin PF05808.6 KKK25730.1 - 0.11 12.0 0.0 0.22 11.0 0.0 1.5 1 0 0 1 1 1 0 Podoplanin DUF3377 PF11857.3 KKK25730.1 - 0.11 12.1 0.1 0.69 9.5 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) DUF3384 PF11864.3 KKK25731.1 - 1.5e-101 340.2 0.7 2.3e-101 339.5 0.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3384) Rap_GAP PF02145.10 KKK25731.1 - 9.2e-56 188.1 0.0 1.5e-55 187.5 0.0 1.3 1 0 0 1 1 1 1 Rap/ran-GAP Tuberin PF03542.11 KKK25731.1 - 1.2e-28 100.1 0.9 2e-27 96.2 0.0 2.6 3 0 0 3 3 3 1 Tuberin DUF2435 PF10363.4 KKK25731.1 - 0.056 13.3 0.1 22 5.0 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2435) DUF3317 PF11779.3 KKK25732.1 - 1.6e-24 85.0 3.2 2.5e-24 84.4 2.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3317) RF-1 PF00472.15 KKK25733.1 - 1.4e-25 89.2 2.2 1.9e-25 88.8 1.5 1.2 1 0 0 1 1 1 1 RF-1 domain ECH PF00378.15 KKK25734.1 - 1e-27 96.8 0.0 1.3e-27 96.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family DUF2346 PF09803.4 KKK25735.1 - 0.0052 16.6 4.3 0.013 15.3 3.0 1.7 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2346) Vps51 PF08700.6 KKK25736.1 - 4.4e-16 58.4 0.2 4.4e-15 55.2 0.0 2.8 2 0 0 2 2 2 1 Vps51/Vps67 Vps53_N PF04100.7 KKK25736.1 - 0.00055 18.8 0.1 0.002 16.9 0.1 1.9 2 0 0 2 2 2 1 Vps53-like, N-terminal Uso1_p115_head PF04869.9 KKK25736.1 - 0.014 14.1 0.2 0.034 12.8 0.1 1.6 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, head region Apolipoprotein PF01442.13 KKK25736.1 - 0.59 9.5 7.7 2.6 7.5 0.8 3.3 2 2 1 3 3 3 0 Apolipoprotein A1/A4/E domain D123 PF07065.9 KKK25737.1 - 3.5e-90 302.1 0.0 3.4e-88 295.5 0.0 2.1 1 1 0 1 1 1 1 D123 CENP-I PF07778.6 KKK25738.1 - 2e-88 296.8 0.1 3.1e-88 296.2 0.1 1.1 1 0 0 1 1 1 1 Mis6 CLPTM1 PF05602.7 KKK25739.1 - 3.4e-173 576.3 0.0 4.2e-173 576.0 0.0 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) adh_short PF00106.20 KKK25740.1 - 6.8e-11 42.3 0.0 1.2e-10 41.5 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KKK25740.1 - 0.0043 16.7 0.0 0.0077 15.9 0.0 1.3 1 0 0 1 1 1 1 KR domain DUF1640 PF07798.6 KKK25741.1 - 1.2e-10 41.7 3.8 1.9e-10 41.0 2.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) Syntaxin-6_N PF09177.6 KKK25741.1 - 0.13 12.6 2.8 0.32 11.4 1.6 2.0 1 1 0 1 1 1 0 Syntaxin 6, N-terminal ALMT PF11744.3 KKK25741.1 - 0.31 9.6 2.6 0.44 9.1 1.8 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter PUF PF00806.14 KKK25742.1 - 3.1e-66 215.2 14.4 8.6e-10 37.5 0.0 8.5 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat Tyr-DNA_phospho PF06087.7 KKK25743.1 - 2.3e-76 257.2 0.0 4.8e-59 200.1 0.0 2.1 1 1 1 2 2 2 2 Tyrosyl-DNA phosphodiesterase UIM PF02809.15 KKK25743.1 - 0.00011 21.4 7.7 0.0065 15.9 0.7 2.6 2 0 0 2 2 2 2 Ubiquitin interaction motif HA2 PF04408.18 KKK25744.1 - 2e-20 72.6 0.8 6.5e-20 71.0 0.0 2.3 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 KKK25744.1 - 1.7e-14 53.4 0.0 1.4e-13 50.5 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.11 KKK25744.1 - 1.6e-09 37.5 0.0 4.7e-09 36.0 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.24 KKK25744.1 - 6.7e-09 35.4 0.3 2.2e-08 33.7 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KKK25744.1 - 0.00026 21.1 1.3 0.0048 17.0 0.0 2.7 3 0 0 3 3 3 1 AAA domain T2SE PF00437.15 KKK25744.1 - 0.0041 16.0 0.0 0.0096 14.8 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein ResIII PF04851.10 KKK25744.1 - 0.061 13.1 0.0 0.33 10.7 0.0 3.5 5 0 0 5 5 5 0 Type III restriction enzyme, res subunit Phage_G PF02306.10 KKK25744.1 - 0.19 11.3 0.0 0.36 10.4 0.0 1.4 1 0 0 1 1 1 0 Major spike protein (G protein) CDP-OH_P_transf PF01066.16 KKK25745.1 - 7.6e-17 61.4 5.4 1.4e-16 60.6 3.7 1.4 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase Transcrip_reg PF01709.15 KKK25746.1 - 3.3e-62 209.6 1.7 4.4e-62 209.2 1.2 1.2 1 0 0 1 1 1 1 Transcriptional regulator HEAT_2 PF13646.1 KKK25747.1 - 2.3e-14 53.4 0.2 0.11 12.7 0.0 7.4 5 1 1 6 6 6 4 HEAT repeats HEAT PF02985.17 KKK25747.1 - 1.2e-07 31.1 13.3 0.071 13.2 0.0 9.5 10 0 0 10 10 10 2 HEAT repeat CLASP_N PF12348.3 KKK25747.1 - 6.8e-05 22.3 1.9 0.36 10.1 0.0 4.7 4 0 0 4 4 4 2 CLASP N terminal Vac14_Fab1_bd PF12755.2 KKK25747.1 - 0.036 14.4 0.0 12 6.3 0.0 4.3 4 0 0 4 4 4 0 Vacuolar 14 Fab1-binding region STAG PF08514.6 KKK25747.1 - 0.064 12.9 0.0 0.41 10.3 0.0 2.4 1 0 0 1 1 1 0 STAG domain DUF2372 PF10178.4 KKK25748.1 - 0.074 13.1 0.0 0.19 11.8 0.0 1.7 1 1 0 1 1 1 0 Uncharacterised conserved protein (DUF2372) cwf21 PF08312.7 KKK25749.1 - 2.1e-19 69.0 13.4 2.1e-19 69.0 9.3 2.8 1 1 1 2 2 2 1 cwf21 domain ABC2_membrane PF01061.19 KKK25750.1 - 1.7e-88 295.3 61.2 6.4e-45 152.9 21.6 2.9 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 KKK25750.1 - 3.1e-38 131.1 0.8 5.6e-20 72.0 0.0 3.1 3 0 0 3 3 2 2 ABC transporter PDR_CDR PF06422.7 KKK25750.1 - 1.5e-29 101.6 8.4 3.1e-27 94.2 0.0 3.2 3 0 0 3 3 2 2 CDR ABC transporter ABC_trans_N PF14510.1 KKK25750.1 - 7.1e-08 32.4 0.1 1.9e-07 31.0 0.0 1.8 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal cobW PF02492.14 KKK25750.1 - 5.9e-06 25.8 0.1 0.0014 18.1 0.0 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain ABC2_membrane_3 PF12698.2 KKK25750.1 - 8.8e-06 24.9 37.0 0.00081 18.5 8.7 2.6 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_22 PF13401.1 KKK25750.1 - 1.4e-05 25.2 0.4 0.02 15.0 0.0 3.4 4 0 0 4 4 2 1 AAA domain AAA_25 PF13481.1 KKK25750.1 - 1.7e-05 24.2 0.0 0.28 10.5 0.1 2.9 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 KKK25750.1 - 3.3e-05 23.9 0.2 0.0041 17.1 0.1 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.1 KKK25750.1 - 3.8e-05 23.6 0.9 0.01 15.7 0.0 3.0 3 0 0 3 3 2 1 AAA domain DUF258 PF03193.11 KKK25750.1 - 4.5e-05 22.6 0.0 0.002 17.3 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_17 PF13207.1 KKK25750.1 - 7.5e-05 23.5 0.0 0.03 15.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 KKK25750.1 - 0.00013 21.5 0.0 0.56 9.6 0.0 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_21 PF13304.1 KKK25750.1 - 0.00014 21.9 1.8 0.58 10.0 0.0 3.6 3 1 0 4 4 4 2 AAA domain MMR_HSR1 PF01926.18 KKK25750.1 - 0.00026 20.9 0.0 0.29 11.1 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_28 PF13521.1 KKK25750.1 - 0.00031 20.7 0.0 0.0019 18.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KKK25750.1 - 0.00036 20.8 0.0 0.012 15.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 KKK25750.1 - 0.00045 19.6 3.3 0.27 10.7 0.1 3.1 3 0 0 3 3 2 2 P-loop containing region of AAA domain UPF0079 PF02367.12 KKK25750.1 - 0.00061 19.4 0.5 0.075 12.6 0.2 2.5 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 NACHT PF05729.7 KKK25750.1 - 0.002 17.8 0.3 0.24 11.0 0.2 2.6 2 0 0 2 2 2 1 NACHT domain SMC_N PF02463.14 KKK25750.1 - 0.0043 16.3 0.5 0.083 12.1 0.0 2.9 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_24 PF13479.1 KKK25750.1 - 0.0092 15.5 0.1 0.45 10.0 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 KKK25750.1 - 0.012 15.0 0.0 1.9 7.8 0.0 2.3 2 0 0 2 2 2 0 AAA-like domain NB-ARC PF00931.17 KKK25750.1 - 0.022 13.6 0.1 4.7 5.9 0.2 2.8 3 0 0 3 3 3 0 NB-ARC domain Miro PF08477.8 KKK25750.1 - 0.024 15.1 0.0 1.4 9.4 0.0 2.8 2 0 0 2 2 2 0 Miro-like protein Dynamin_N PF00350.18 KKK25750.1 - 0.029 14.1 0.2 1.5 8.6 0.0 3.2 3 0 0 3 3 3 0 Dynamin family AAA PF00004.24 KKK25750.1 - 0.058 13.5 0.0 18 5.5 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Septin PF00735.13 KKK25750.1 - 0.064 12.2 0.2 0.31 10.0 0.1 1.9 2 0 0 2 2 2 0 Septin AAA_30 PF13604.1 KKK25750.1 - 0.077 12.5 1.3 2.3 7.7 0.4 2.4 2 0 0 2 2 2 0 AAA domain T2SE PF00437.15 KKK25750.1 - 0.1 11.4 0.0 3.1 6.6 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein Zeta_toxin PF06414.7 KKK25750.1 - 0.15 11.1 0.9 1.3 8.0 0.3 2.2 2 0 0 2 2 2 0 Zeta toxin PduV-EutP PF10662.4 KKK25750.1 - 0.17 11.3 0.2 0.55 9.7 0.2 1.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_15 PF13175.1 KKK25750.1 - 0.22 10.5 0.0 11 4.9 0.0 2.4 1 1 1 2 2 2 0 AAA ATPase domain AAA_19 PF13245.1 KKK25750.1 - 0.27 11.0 4.4 11 5.8 0.0 3.0 3 0 0 3 3 2 0 Part of AAA domain Guanylate_kin PF00625.16 KKK25750.1 - 1.5 8.1 3.2 31 3.9 0.0 3.0 3 0 0 3 3 3 0 Guanylate kinase DUF1382 PF07131.6 KKK25751.1 - 0.13 12.3 0.0 0.3 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1382) CAS_CSE1 PF03378.10 KKK25752.1 - 1.3e-190 633.2 0.0 3.8e-190 631.8 0.0 1.8 1 0 0 1 1 1 1 CAS/CSE protein, C-terminus Cse1 PF08506.5 KKK25752.1 - 1e-156 521.1 1.6 1.5e-156 520.6 1.1 1.2 1 0 0 1 1 1 1 Cse1 IBN_N PF03810.14 KKK25752.1 - 9.6e-15 54.2 0.2 3.9e-14 52.3 0.2 2.2 1 0 0 1 1 1 1 Importin-beta N-terminal domain Xpo1 PF08389.7 KKK25752.1 - 0.0057 16.5 3.5 0.038 13.8 0.0 4.0 5 1 1 6 6 6 1 Exportin 1-like protein HEAT_2 PF13646.1 KKK25752.1 - 0.08 13.2 0.0 1.9 8.8 0.0 2.9 2 0 0 2 2 2 0 HEAT repeats UCH_1 PF13423.1 KKK25758.1 - 1.5e-67 228.1 0.5 2e-67 227.7 0.4 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.19 KKK25758.1 - 4.4e-22 79.1 0.0 1.1e-21 77.8 0.0 1.7 1 0 0 1 1 1 1 Exonuclease UCH PF00443.24 KKK25758.1 - 1.1e-09 37.7 0.1 2.2e-08 33.5 0.1 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase VHS PF00790.14 KKK25759.1 - 1.4e-31 108.9 0.6 5.6e-24 84.3 0.0 2.4 2 0 0 2 2 2 2 VHS domain SH3_1 PF00018.23 KKK25759.1 - 8.6e-16 57.0 0.0 1.8e-15 56.0 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KKK25759.1 - 1.5e-15 56.5 0.1 2.6e-15 55.7 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KKK25759.1 - 3.1e-14 52.2 0.0 5.9e-14 51.3 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain UIM PF02809.15 KKK25759.1 - 0.042 13.4 1.9 0.12 11.9 1.3 1.9 1 0 0 1 1 1 0 Ubiquitin interaction motif Antimicrobial11 PF08106.6 KKK25759.1 - 0.36 10.7 7.5 0.88 9.4 0.1 3.0 2 0 0 2 2 2 0 Formaecin family CPSF_A PF03178.10 KKK25760.1 - 1.7e-99 332.9 0.0 3e-98 328.8 0.0 2.5 3 0 0 3 3 3 1 CPSF A subunit region MMS1_N PF10433.4 KKK25760.1 - 1.3e-69 234.7 0.0 2.2e-69 233.9 0.0 1.4 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term BBS2_N PF14781.1 KKK25760.1 - 0.0037 16.8 0.0 1.8 8.1 0.0 3.2 3 0 0 3 3 3 2 Ciliary BBSome complex subunit 2, N-terminal WD40 PF00400.27 KKK25760.1 - 0.36 10.7 1.3 0.85 9.5 0.1 2.4 2 0 0 2 2 2 0 WD domain, G-beta repeat ubiquitin PF00240.18 KKK25761.1 - 2.4e-19 68.4 0.0 4e-19 67.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.26 KKK25761.1 - 3.7e-09 36.1 0.1 1.2e-08 34.4 0.1 2.0 1 0 0 1 1 1 1 UBA/TS-N domain Rad60-SLD PF11976.3 KKK25761.1 - 3.3e-08 33.0 0.0 5.2e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like YukD PF08817.5 KKK25761.1 - 3.3e-05 24.3 0.0 6e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukD DUF2407 PF10302.4 KKK25761.1 - 6.5e-05 23.0 0.0 0.00012 22.1 0.0 1.4 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.1 KKK25761.1 - 7.4e-05 22.6 0.0 0.00013 21.7 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 KKK25761.1 - 0.12 12.6 0.0 0.3 11.3 0.0 1.7 1 1 0 1 1 1 0 Ubiquitin-like domain UDG PF03167.14 KKK25762.1 - 8.9e-21 73.9 0.0 1.6e-20 73.1 0.0 1.4 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Sporozoite_P67 PF05642.6 KKK25762.1 - 0.011 13.6 1.7 0.014 13.2 1.2 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RhoGEF PF00621.15 KKK25764.1 - 4.4e-20 72.2 0.6 9.1e-20 71.2 0.4 1.6 1 0 0 1 1 1 1 RhoGEF domain SBDS PF01172.13 KKK25765.1 - 4.1e-24 84.1 0.0 4.7e-24 83.9 0.0 1.0 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein XkdN PF08890.6 KKK25765.1 - 0.0065 16.2 0.0 0.017 14.8 0.0 1.6 2 0 0 2 2 2 1 Phage XkdN-like protein BP28CT PF08146.7 KKK25766.1 - 7.1e-46 155.7 0.3 3.1e-45 153.6 0.2 2.2 1 0 0 1 1 1 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.3 KKK25766.1 - 2.6e-33 114.5 11.4 2.4e-30 104.9 0.8 5.8 7 0 0 7 7 7 2 U3 small nucleolar RNA-associated protein 10 HEAT_2 PF13646.1 KKK25766.1 - 2.3e-10 40.6 5.1 0.011 16.0 0.1 5.6 5 0 0 5 5 5 3 HEAT repeats HEAT PF02985.17 KKK25766.1 - 8.1e-06 25.5 4.5 0.033 14.2 0.0 6.2 6 0 0 6 6 6 1 HEAT repeat Arm PF00514.18 KKK25766.1 - 0.42 10.5 6.8 3.4 7.6 0.1 4.5 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.1 KKK25766.1 - 4.1 8.0 25.5 0.099 13.1 0.6 7.9 9 2 2 11 11 11 0 HEAT-like repeat Bul1_N PF04425.7 KKK25767.1 - 5.4e-14 51.6 3.2 5.4e-09 35.1 1.4 2.4 2 1 0 2 2 2 2 Bul1 N terminus Arrestin_N PF00339.24 KKK25767.1 - 0.00033 20.4 0.0 0.00064 19.5 0.0 1.6 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Bul1_C PF04426.7 KKK25767.1 - 0.011 14.9 0.1 0.023 13.9 0.0 1.5 2 0 0 2 2 2 0 Bul1 C terminus FAD_binding_8 PF08022.7 KKK25768.1 - 4.9e-22 77.7 0.0 1.1e-21 76.6 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 KKK25768.1 - 5.6e-22 78.3 0.0 8.6e-22 77.7 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 KKK25768.1 - 4e-17 62.4 12.3 8.9e-17 61.3 8.6 1.6 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 KKK25768.1 - 4.8e-05 23.4 0.0 0.00016 21.7 0.0 1.8 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain Engrail_1_C_sig PF10525.4 KKK25768.1 - 0.17 10.9 0.2 8.3 5.6 0.1 2.3 2 0 0 2 2 2 0 Engrailed homeobox C-terminal signature domain NRDE-2 PF08424.5 KKK25769.1 - 8.7e-73 245.0 4.6 3.5e-56 190.4 0.1 3.4 2 1 1 3 3 3 2 NRDE-2, necessary for RNA interference TPR_14 PF13428.1 KKK25769.1 - 0.0017 18.8 0.1 6.7 7.6 0.0 4.6 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 KKK25769.1 - 0.024 15.3 0.2 1.1 10.0 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Corona_nucleoca PF00937.13 KKK25769.1 - 3.1 6.6 12.1 5.4 5.8 8.4 1.3 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Ran_BP1 PF00638.13 KKK25770.1 - 6.5e-14 52.0 0.0 1.2e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 RanBP1 domain SNF2_N PF00176.18 KKK25771.1 - 8.5e-71 238.1 0.3 1.4e-70 237.4 0.2 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KKK25771.1 - 1.3e-11 44.2 0.0 3.8e-11 42.7 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.1 KKK25771.1 - 1.7e-09 37.5 9.9 6.9e-09 35.5 3.7 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KKK25771.1 - 2.6e-09 36.6 4.9 3e-08 33.2 1.7 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.10 KKK25771.1 - 1.3e-07 31.6 0.0 3.6e-06 26.9 0.0 2.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 KKK25771.1 - 2.7e-07 30.2 0.0 3.4e-06 26.6 0.0 2.4 2 1 0 2 2 2 1 DEAD/DEAH box helicase zf-RING_2 PF13639.1 KKK25771.1 - 5.4e-07 29.3 4.4 5.4e-07 29.3 3.0 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 KKK25771.1 - 7.1e-06 25.5 8.3 1.1e-05 25.0 2.7 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KKK25771.1 - 1.6e-05 24.5 3.2 1.6e-05 24.5 2.2 2.6 3 0 0 3 3 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 KKK25771.1 - 0.00031 20.5 6.2 0.00031 20.5 4.3 2.1 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 KKK25771.1 - 0.0017 18.0 1.8 0.0047 16.6 1.2 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_4 PF14570.1 KKK25771.1 - 0.0024 17.4 4.7 0.0024 17.4 3.2 2.2 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-MIZ PF02891.15 KKK25771.1 - 0.74 9.3 5.6 2.7 7.5 3.9 2.0 1 1 0 1 1 1 0 MIZ/SP-RING zinc finger Baculo_IE-1 PF05290.6 KKK25771.1 - 1.3 8.7 4.5 0.68 9.6 0.3 2.3 2 0 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) SCP2 PF02036.12 KKK25772.1 - 1.8e-23 82.7 0.3 2.3e-23 82.3 0.2 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.1 KKK25772.1 - 2.2e-08 34.1 0.1 2.7e-08 33.8 0.1 1.1 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal PDZ_2 PF13180.1 KKK25773.1 - 2.3e-07 30.5 0.0 4.7e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.19 KKK25773.1 - 1.4e-05 25.2 0.0 2.5e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) GRASP55_65 PF04495.9 KKK25773.1 - 4.5e-05 23.4 0.0 7.4e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 GRASP55/65 PDZ-like domain HMA PF00403.21 KKK25773.1 - 0.05 13.7 0.1 0.17 12.0 0.0 1.9 2 0 0 2 2 2 0 Heavy-metal-associated domain Ras PF00071.17 KKK25774.1 - 1.6e-41 141.4 0.0 2.1e-41 140.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KKK25774.1 - 1.7e-08 34.9 0.0 3.8e-08 33.8 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 KKK25774.1 - 4.6e-06 25.9 0.1 6.4e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Ribosomal_S13 PF00416.17 KKK25775.1 - 7.1e-23 81.0 0.5 8.4e-23 80.8 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 Peptidase_S10 PF00450.17 KKK25776.1 - 5.4e-129 430.9 0.1 6.6e-129 430.6 0.1 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Carbpep_Y_N PF05388.6 KKK25776.1 - 2.8e-06 27.4 0.0 5.6e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Carboxypeptidase Y pro-peptide Abhydrolase_6 PF12697.2 KKK25776.1 - 0.00075 19.4 0.0 0.021 14.6 0.0 2.7 3 1 0 3 3 3 1 Alpha/beta hydrolase family SBDS_C PF09377.5 KKK25777.1 - 2.9e-50 169.1 0.0 4.3e-50 168.6 0.0 1.3 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.13 KKK25777.1 - 2.8e-26 91.1 0.1 6.3e-26 89.9 0.1 1.6 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein PALP PF00291.20 KKK25778.1 - 1.7e-33 116.2 1.9 1.4e-32 113.1 1.3 1.9 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Pyridoxal_deC PF00282.14 KKK25780.1 - 1.7e-77 260.3 0.0 2.2e-77 260.0 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Sulfatase PF00884.18 KKK25783.1 - 4.5e-58 196.8 0.3 6.3e-58 196.3 0.2 1.2 1 0 0 1 1 1 1 Sulfatase Choline_sulf_C PF12411.3 KKK25783.1 - 5.3e-21 74.2 0.1 1.2e-20 73.0 0.1 1.7 1 0 0 1 1 1 1 Choline sulfatase enzyme C terminal Phosphodiest PF01663.17 KKK25783.1 - 4.4e-11 42.7 0.1 9.1e-05 21.9 0.0 2.2 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase_C PF14707.1 KKK25783.1 - 0.0067 16.7 0.0 0.015 15.5 0.0 1.6 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase DUF229 PF02995.12 KKK25783.1 - 0.0084 14.5 0.0 0.011 14.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF229) DUF1501 PF07394.7 KKK25783.1 - 0.034 12.9 0.0 0.057 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) EMP70 PF02990.11 KKK25784.1 - 1.3e-153 512.1 0.0 3.5e-153 510.8 0.0 1.7 1 1 0 1 1 1 1 Endomembrane protein 70 DUF935 PF06074.7 KKK25814.1 - 0.11 11.2 0.1 0.12 11.0 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF935) Ecl1 PF12855.2 KKK25815.1 - 1.4e-10 40.2 2.4 1.3e-09 37.1 0.7 2.2 2 0 0 2 2 2 1 Life-span regulatory factor DUF581 PF04570.9 KKK25815.1 - 0.042 13.1 0.3 0.084 12.1 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF581) RRM_1 PF00076.17 KKK25816.1 - 8.8e-37 124.5 0.0 8.7e-12 44.5 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KKK25816.1 - 1.6e-36 124.0 0.1 2.3e-09 37.1 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KKK25816.1 - 6.2e-17 61.2 0.1 0.0016 18.2 0.1 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM PF10378.4 KKK25816.1 - 5.5e-14 51.4 10.1 5.6e-14 51.4 5.0 2.6 2 0 0 2 2 2 1 Putative RRM domain RRM_3 PF08777.6 KKK25816.1 - 0.00012 21.8 0.0 0.2 11.4 0.0 2.6 2 0 0 2 2 2 2 RNA binding motif RNA_bind PF08675.6 KKK25816.1 - 0.074 13.0 0.0 1.8 8.6 0.0 3.0 3 1 0 3 3 3 0 RNA binding domain NID PF07292.8 KKK25816.1 - 0.13 12.2 0.0 0.44 10.6 0.0 1.9 1 0 0 1 1 1 0 Nmi/IFP 35 domain (NID) tRNA-synt_2 PF00152.15 KKK25817.1 - 3.8e-73 246.1 0.3 6.2e-73 245.4 0.0 1.5 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 KKK25817.1 - 1.6e-05 24.6 0.0 2.7e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain BcsB PF03170.8 KKK25817.1 - 0.071 11.1 0.1 0.1 10.6 0.0 1.2 1 0 0 1 1 1 0 Bacterial cellulose synthase subunit Apolipoprotein PF01442.13 KKK25818.1 - 0.0083 15.6 2.9 0.013 15.0 2.0 1.3 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain ATP-synt_B PF00430.13 KKK25818.1 - 0.0085 15.8 0.9 0.016 14.9 0.6 1.4 1 0 0 1 1 1 1 ATP synthase B/B' CF(0) DUF883 PF05957.8 KKK25818.1 - 0.29 11.5 1.5 0.77 10.2 0.9 1.7 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF1762 PF08574.5 KKK25819.1 - 7.7e-23 80.7 7.3 7.7e-23 80.7 5.0 2.1 3 0 0 3 3 3 1 Protein of unknown function (DUF1762) Filament PF00038.16 KKK25828.1 - 3e-05 23.6 34.7 0.0022 17.5 24.1 2.2 1 1 0 1 1 1 1 Intermediate filament protein DUF812 PF05667.6 KKK25828.1 - 5.3e-05 21.9 20.6 6.9e-05 21.5 14.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF812) Reo_sigmaC PF04582.7 KKK25828.1 - 8.6e-05 21.8 1.8 0.014 14.6 0.1 2.2 1 1 1 2 2 2 2 Reovirus sigma C capsid protein APG6 PF04111.7 KKK25828.1 - 0.0012 17.9 37.1 0.0059 15.6 12.1 2.1 1 1 1 2 2 2 2 Autophagy protein Apg6 Cep57_MT_bd PF06657.8 KKK25828.1 - 0.017 15.0 3.1 0.017 15.0 2.1 4.4 2 2 1 3 3 3 0 Centrosome microtubule-binding domain of Cep57 Phyto_Pns9_10 PF05878.6 KKK25828.1 - 0.038 13.0 9.7 0.056 12.4 6.7 1.3 1 0 0 1 1 1 0 Phytoreovirus nonstructural protein Pns9/Pns10 SlyX PF04102.7 KKK25828.1 - 0.058 13.7 16.8 0.8 10.1 0.3 5.0 2 2 3 5 5 5 0 SlyX TMPIT PF07851.8 KKK25828.1 - 0.14 11.2 23.3 0.063 12.3 3.9 2.5 1 1 0 2 2 2 0 TMPIT-like protein Bacillus_HBL PF05791.6 KKK25828.1 - 0.21 10.9 14.1 0.12 11.7 1.7 2.8 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) IncA PF04156.9 KKK25828.1 - 0.4 10.2 33.3 1.2 8.6 9.6 2.7 1 1 1 2 2 2 0 IncA protein ADIP PF11559.3 KKK25828.1 - 0.45 10.4 34.8 0.25 11.2 10.0 2.8 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding Spc7 PF08317.6 KKK25828.1 - 0.96 8.0 30.6 0.38 9.3 9.1 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein ATG16 PF08614.6 KKK25828.1 - 1.1 9.0 32.1 2.7 7.7 5.6 3.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) TMCO5 PF14992.1 KKK25828.1 - 1.2 8.1 25.2 0.47 9.5 8.0 2.2 1 1 1 2 2 2 0 TMCO5 family Atg14 PF10186.4 KKK25828.1 - 1.6 7.5 30.8 1.7 7.5 7.7 2.3 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 BLOC1_2 PF10046.4 KKK25828.1 - 1.9 8.6 17.2 0.85 9.7 1.3 3.4 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF3584 PF12128.3 KKK25828.1 - 2.4 5.3 33.6 0.9 6.7 9.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) TPR_MLP1_2 PF07926.7 KKK25828.1 - 2.4 7.9 32.6 0.6 9.8 10.6 2.8 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein Tup_N PF08581.5 KKK25828.1 - 3.3 7.9 29.3 0.47 10.6 4.9 3.4 3 0 0 3 3 3 0 Tup N-terminal L31 PF09784.4 KKK25828.1 - 3.7 7.6 14.4 0.13 12.3 1.9 2.5 1 1 1 2 2 2 0 Mitochondrial ribosomal protein L31 TSC22 PF01166.13 KKK25828.1 - 6.8 6.7 16.1 0.51 10.3 0.1 4.2 2 2 2 4 4 4 0 TSC-22/dip/bun family DUF2265 PF10023.4 KKK25828.1 - 7.4 5.6 21.6 8.6 5.3 4.7 3.2 1 1 2 3 3 3 0 Predicted aminopeptidase (DUF2265) FH2 PF02181.18 KKK25828.1 - 7.4 5.3 22.3 2.7 6.8 6.6 2.5 1 1 1 2 2 2 0 Formin Homology 2 Domain CorA PF01544.13 KKK25828.1 - 9 5.2 19.1 2.8 6.8 0.3 2.8 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein DUF3106 PF11304.3 KKK25828.1 - 9.1 6.7 19.5 1.2 9.5 5.9 3.3 1 1 2 3 3 3 0 Protein of unknown function (DUF3106) PCI PF01399.22 KKK25830.1 - 2.2e-11 43.9 0.0 4.5e-11 42.9 0.0 1.6 1 0 0 1 1 1 1 PCI domain RPN7 PF10602.4 KKK25830.1 - 6.4e-08 32.1 0.8 1e-07 31.4 0.6 1.3 1 0 0 1 1 1 1 26S proteasome subunit RPN7 TPR_19 PF14559.1 KKK25830.1 - 0.004 17.4 1.8 0.01 16.1 0.0 2.7 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 KKK25830.1 - 0.065 13.0 0.3 7.9 6.5 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Herpes_UL14 PF03580.9 KKK25830.1 - 0.31 10.8 4.9 6.6 6.5 0.8 2.4 1 1 1 2 2 2 0 Herpesvirus UL14-like protein TPR_14 PF13428.1 KKK25830.1 - 3.6 8.4 10.4 17 6.3 0.8 4.8 5 1 1 6 6 6 0 Tetratricopeptide repeat FAD_binding_2 PF00890.19 KKK25831.1 - 9.7e-85 284.9 1.4 1.2e-84 284.6 0.9 1.1 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.23 KKK25831.1 - 6.3e-21 73.9 1.2 6.5e-19 67.5 0.0 3.3 4 0 0 4 4 4 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.19 KKK25831.1 - 8.4e-13 47.9 2.8 3.2e-12 46.0 1.9 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 KKK25831.1 - 8.7e-10 38.2 0.8 3.3e-09 36.3 0.6 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KKK25831.1 - 8.5e-09 35.3 2.1 5e-08 32.8 0.2 3.0 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KKK25831.1 - 3.6e-08 33.5 0.0 5e-06 26.5 0.0 2.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KKK25831.1 - 1.3e-06 27.1 4.7 0.0029 16.1 0.2 3.2 3 0 0 3 3 3 2 HI0933-like protein Thi4 PF01946.12 KKK25831.1 - 8.7e-05 21.7 1.0 0.011 14.8 0.4 2.6 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.14 KKK25831.1 - 0.0003 19.9 0.6 0.00071 18.7 0.4 1.5 1 1 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.19 KKK25831.1 - 0.00045 19.4 0.4 0.1 11.6 0.0 2.6 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase GIDA PF01134.17 KKK25831.1 - 0.001 18.0 2.9 0.22 10.3 0.6 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A NAD_binding_9 PF13454.1 KKK25831.1 - 0.0013 18.5 0.8 0.0069 16.1 0.6 2.2 1 1 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 KKK25831.1 - 0.02 14.9 1.2 0.088 12.8 0.9 2.1 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KKK25831.1 - 0.053 13.9 2.0 3.6 8.0 0.3 2.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GDI PF00996.13 KKK25831.1 - 0.26 9.5 0.1 0.42 8.8 0.1 1.2 1 0 0 1 1 1 0 GDP dissociation inhibitor zf-CCCH PF00642.19 KKK25832.1 - 6.5e-13 48.0 29.6 7.5e-06 25.4 1.0 5.2 5 0 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3H1 PF10650.4 KKK25832.1 - 1.6 8.3 5.2 0.7 9.4 0.0 2.8 3 0 0 3 3 3 0 Putative zinc-finger domain TFIIF_beta PF02270.10 KKK25833.1 - 2.3e-86 290.0 4.2 2.7e-86 289.7 2.9 1.0 1 0 0 1 1 1 1 Transcription initiation factor IIF, beta subunit DUF859 PF05895.7 KKK25833.1 - 0.15 10.2 0.0 0.2 9.8 0.0 1.1 1 0 0 1 1 1 0 Siphovirus protein of unknown function (DUF859) Sel1 PF08238.7 KKK25834.1 - 6e-17 61.6 1.9 4.6e-07 30.2 0.0 3.6 3 0 0 3 3 3 3 Sel1 repeat bZIP_Maf PF03131.12 KKK25835.1 - 1.3e-07 31.7 10.5 1.3e-07 31.7 7.3 2.4 2 0 0 2 2 2 1 bZIP Maf transcription factor bZIP_2 PF07716.10 KKK25835.1 - 1.6e-06 27.8 19.4 4.6e-06 26.3 8.4 2.6 2 0 0 2 2 2 2 Basic region leucine zipper bZIP_1 PF00170.16 KKK25835.1 - 3.7e-06 26.7 20.3 1.7e-05 24.6 9.7 2.5 2 0 0 2 2 2 2 bZIP transcription factor Herpes_U5 PF05999.6 KKK25835.1 - 0.011 14.3 1.7 0.017 13.7 1.2 1.1 1 0 0 1 1 1 0 Herpesvirus U5-like family Endotoxin_N PF03945.9 KKK25835.1 - 0.75 9.1 7.1 0.15 11.4 2.4 1.7 2 0 0 2 2 2 0 delta endotoxin, N-terminal domain CBF PF03914.12 KKK25836.1 - 5.8e-49 165.6 0.1 1.1e-48 164.7 0.0 1.5 1 0 0 1 1 1 1 CBF/Mak21 family LemA PF04011.7 KKK25836.1 - 0.044 12.9 0.2 0.095 11.7 0.2 1.5 1 0 0 1 1 1 0 LemA family Mt_ATP-synt_B PF05405.9 KKK25837.1 - 9.1e-53 178.0 8.2 1.2e-52 177.7 5.7 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) DUF1539 PF07560.6 KKK25837.1 - 0.066 13.0 0.6 0.2 11.5 0.2 1.8 1 1 1 2 2 2 0 Domain of Unknown Function (DUF1539) DUF3573 PF12097.3 KKK25837.1 - 0.11 11.0 0.6 0.15 10.6 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Herpes_UL95 PF03038.9 KKK25837.1 - 0.42 9.4 3.0 0.6 8.9 2.1 1.1 1 0 0 1 1 1 0 UL95 family GPI-anchored PF10342.4 KKK25838.1 - 1.3e-15 57.6 1.8 1.3e-15 57.6 1.2 1.6 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Big_5 PF13205.1 KKK25838.1 - 0.0039 17.7 1.5 0.0073 16.8 0.1 2.0 2 0 0 2 2 2 1 Bacterial Ig-like domain APG6 PF04111.7 KKK25840.1 - 1.1e-126 422.1 0.0 1.6e-126 421.6 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Apg6 Amidase PF01425.16 KKK25841.1 - 2.8e-93 313.2 0.0 3.3e-93 312.9 0.0 1.1 1 0 0 1 1 1 1 Amidase DUF1815 PF08844.5 KKK25841.1 - 0.072 12.7 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1815) Arylsulfotran_2 PF14269.1 KKK25842.1 - 2.9e-43 148.1 0.1 4.3e-43 147.5 0.1 1.3 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.6 KKK25842.1 - 2.5e-14 52.6 0.1 6.5e-13 48.0 0.0 2.0 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) TPP_enzyme_N PF02776.13 KKK25843.1 - 1e-46 158.5 0.2 4.7e-45 153.1 0.0 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 KKK25843.1 - 2.7e-35 121.0 0.1 5.9e-35 119.9 0.1 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 KKK25843.1 - 4.4e-17 62.0 0.1 1e-16 60.8 0.1 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain CO_dh PF02552.11 KKK25843.1 - 0.16 11.5 0.0 0.27 10.7 0.0 1.3 1 0 0 1 1 1 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit Piwi PF02171.12 KKK25844.1 - 3e-69 233.3 0.0 4.7e-69 232.6 0.0 1.3 1 0 0 1 1 1 1 Piwi domain DUF1785 PF08699.5 KKK25844.1 - 2.5e-12 45.9 0.0 1.6e-11 43.4 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF1785) PAZ PF02170.17 KKK25844.1 - 2.1e-09 36.8 0.0 6.1e-09 35.2 0.0 1.7 2 0 0 2 2 2 1 PAZ domain Scm3 PF10384.4 KKK25845.1 - 6.8e-24 83.1 0.3 1.3e-23 82.1 0.2 1.5 1 0 0 1 1 1 1 Centromere protein Scm3 Myb_DNA-binding PF00249.26 KKK25845.1 - 4.2e-06 26.7 0.8 0.022 14.8 0.0 3.1 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KKK25845.1 - 5.3e-06 26.4 2.5 0.0055 16.7 0.2 3.4 3 0 0 3 3 3 2 Myb-like DNA-binding domain PALP PF00291.20 KKK25846.1 - 1e-50 172.7 0.2 1.2e-50 172.4 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme rve PF00665.21 KKK25846.1 - 0.11 12.6 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Integrase core domain Methyltransf_28 PF02636.12 KKK25847.1 - 2.9e-37 128.4 0.0 4e-37 127.9 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase TPR_11 PF13414.1 KKK25848.1 - 5e-27 93.3 5.2 2e-11 43.3 0.2 4.4 2 2 2 4 4 4 4 TPR repeat TPR_1 PF00515.23 KKK25848.1 - 7.7e-24 82.2 2.8 2.5e-08 33.1 0.0 5.8 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.12 KKK25848.1 - 2.7e-23 79.9 2.3 1.6e-07 30.6 0.1 5.9 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_14 PF13428.1 KKK25848.1 - 1.2e-17 62.7 3.7 8.4e-05 22.8 0.0 5.9 5 1 2 7 7 5 3 Tetratricopeptide repeat TPR_16 PF13432.1 KKK25848.1 - 9.4e-16 58.0 7.8 2.5e-06 27.9 0.0 5.0 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_17 PF13431.1 KKK25848.1 - 2.1e-15 55.5 4.6 0.0012 18.8 0.1 5.3 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_19 PF14559.1 KKK25848.1 - 8.2e-13 48.4 2.0 0.0006 20.1 0.0 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 KKK25848.1 - 9.7e-13 47.8 7.6 5.1e-09 35.9 0.2 4.0 4 1 1 5 5 4 3 Tetratricopeptide repeat TPR_7 PF13176.1 KKK25848.1 - 7.4e-12 44.1 1.7 0.0011 18.6 0.0 6.4 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_20 PF14561.1 KKK25848.1 - 2.7e-10 40.2 4.2 0.0043 17.1 0.0 4.9 3 2 2 5 5 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 KKK25848.1 - 4.6e-10 38.5 0.3 0.0004 19.9 0.0 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_9 PF13371.1 KKK25848.1 - 9.2e-07 28.6 3.0 0.0038 17.0 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat Apc3 PF12895.2 KKK25848.1 - 1.7e-06 28.0 1.8 4.7e-05 23.4 0.2 2.5 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 KKK25848.1 - 5.9e-06 26.3 2.2 0.92 10.1 0.0 6.1 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_3 PF07720.7 KKK25848.1 - 0.00045 19.9 0.0 0.096 12.5 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_15 PF13429.1 KKK25848.1 - 0.0015 17.6 0.3 0.58 9.1 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat MIT PF04212.13 KKK25848.1 - 0.0094 15.8 0.9 0.73 9.7 0.2 3.6 3 1 0 3 3 3 1 MIT (microtubule interacting and transport) domain TPR_10 PF13374.1 KKK25848.1 - 0.018 14.9 1.0 0.49 10.3 0.4 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat NatB_MDM20 PF09797.4 KKK25848.1 - 0.037 12.7 0.0 0.072 11.7 0.0 1.4 1 0 0 1 1 1 0 N-acetyltransferase B complex (NatB) non catalytic subunit TOM20_plant PF06552.7 KKK25848.1 - 0.045 13.3 0.1 2.1 7.9 0.0 3.1 3 1 0 3 3 3 0 Plant specific mitochondrial import receptor subunit TOM20 DUF4192 PF13830.1 KKK25848.1 - 0.33 10.5 7.3 1 8.9 0.3 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4192) RRM_1 PF00076.17 KKK25849.1 - 1.3e-31 108.0 0.0 2.3e-18 65.5 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KKK25849.1 - 4.4e-24 84.2 0.1 8.5e-12 44.8 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Fungal_trans PF04082.13 KKK25849.1 - 1.2e-16 60.3 0.7 3.3e-16 58.9 0.0 1.9 1 1 1 2 2 2 1 Fungal specific transcription factor domain RRM_5 PF13893.1 KKK25849.1 - 1.6e-13 50.2 0.0 1.9e-07 30.8 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Zn_clus PF00172.13 KKK25849.1 - 2.9e-06 27.0 11.7 4.9e-06 26.3 8.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HSBP1 PF06825.7 KKK25849.1 - 0.047 13.2 0.1 0.13 11.8 0.1 1.7 1 0 0 1 1 1 0 Heat shock factor binding protein 1 DUF962 PF06127.6 KKK25851.1 - 1.2e-24 86.0 0.1 2.5e-24 84.9 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF962) DUF3852 PF12963.2 KKK25851.1 - 0.2 11.7 0.3 0.2 11.7 0.2 2.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3852) SHS2_Rpb7-N PF03876.12 KKK25852.1 - 5.2e-15 55.3 0.0 9.5e-15 54.4 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.18 KKK25852.1 - 3.4e-09 36.6 0.0 5.2e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 S1 RNA binding domain THF_DHG_CYH PF00763.18 KKK25853.1 - 2.6e-17 62.9 0.0 3.9e-17 62.3 0.0 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.14 KKK25853.1 - 1.5e-12 46.8 0.0 1.4e-09 37.2 0.0 2.6 2 1 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain ATP-synt_ab PF00006.20 KKK25854.1 - 6.9e-71 238.1 0.0 1.1e-70 237.4 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 KKK25854.1 - 1.1e-26 93.4 0.3 3.3e-26 91.9 0.1 1.9 2 0 0 2 2 2 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 KKK25854.1 - 2.6e-15 56.3 3.1 6.4e-15 55.1 2.1 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 KKK25854.1 - 0.0047 16.7 0.9 0.016 15.1 0.6 1.9 1 0 0 1 1 1 1 HAS barrel domain DUF106 PF01956.11 KKK25855.1 - 5.8e-52 175.6 1.1 7.7e-52 175.2 0.7 1.2 1 0 0 1 1 1 1 Integral membrane protein DUF106 SPC25 PF06703.6 KKK25856.1 - 1.2e-50 171.2 0.1 1.5e-50 170.9 0.1 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) MFS_2 PF13347.1 KKK25856.1 - 0.03 12.7 0.3 0.041 12.2 0.2 1.1 1 0 0 1 1 1 0 MFS/sugar transport protein MMS19_C PF12460.3 KKK25857.1 - 1.2e-129 432.6 11.1 1.2e-129 432.6 7.7 2.9 2 1 1 3 3 3 2 RNAPII transcription regulator C-terminal MMS19_N PF14500.1 KKK25857.1 - 1.1e-95 319.9 0.3 3.4e-94 314.9 0.1 2.7 2 0 0 2 2 2 1 Dos2-interacting transcription regulator of RNA-Pol-II HEAT_2 PF13646.1 KKK25857.1 - 3.5e-07 30.3 8.7 1 9.6 0.1 6.7 6 0 0 6 6 6 2 HEAT repeats HEAT PF02985.17 KKK25857.1 - 0.00034 20.4 5.8 3 8.1 0.1 6.1 5 0 0 5 5 5 1 HEAT repeat HEAT_EZ PF13513.1 KKK25857.1 - 0.0019 18.6 13.9 1.4 9.5 0.4 6.1 5 1 0 5 5 5 2 HEAT-like repeat DUF1454 PF07305.7 KKK25857.1 - 0.037 13.1 1.1 1.4 7.9 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1454) Arm PF00514.18 KKK25857.1 - 0.081 12.7 1.4 12 5.9 0.0 3.5 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat DUF3385 PF11865.3 KKK25857.1 - 0.1 12.5 2.6 3.2 7.6 0.0 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF3385) Fasciclin PF02469.17 KKK25858.1 - 9.2e-07 28.9 0.0 1.4e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 Fasciclin domain WD40 PF00400.27 KKK25860.1 - 1.9e-13 49.7 3.6 0.084 12.7 0.2 7.4 8 0 0 8 8 8 5 WD domain, G-beta repeat PAH PF02671.16 KKK25861.1 - 1.6e-46 155.6 2.9 6.1e-17 60.9 0.5 4.4 4 0 0 4 4 4 3 Paired amphipathic helix repeat Sin3_corepress PF08295.7 KKK25861.1 - 4.3e-41 138.7 0.0 1.2e-40 137.2 0.0 1.8 1 0 0 1 1 1 1 Sin3 family co-repressor AcetylCoA_hydro PF02550.10 KKK25862.1 - 2.3e-52 177.6 0.0 3.4e-52 177.1 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain AcetylCoA_hyd_C PF13336.1 KKK25862.1 - 1.8e-37 128.4 0.0 3.2e-37 127.5 0.0 1.5 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain Hex_IIIa PF02455.11 KKK25875.1 - 8.8 4.8 6.6 14 4.2 4.6 1.2 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) Gpi16 PF04113.9 KKK25876.1 - 1.9e-256 851.5 0.0 2.4e-256 851.2 0.0 1.0 1 0 0 1 1 1 1 Gpi16 subunit, GPI transamidase component TFIIS_M PF07500.9 KKK25877.1 - 1.3e-22 80.0 0.0 3e-22 78.8 0.0 1.6 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain SPOC PF07744.8 KKK25877.1 - 4.3e-19 69.1 0.0 8.1e-19 68.2 0.0 1.5 1 0 0 1 1 1 1 SPOC domain PHD PF00628.24 KKK25877.1 - 6.2e-11 41.8 12.7 1.2e-10 40.9 8.8 1.5 1 0 0 1 1 1 1 PHD-finger PHD_3 PF13922.1 KKK25877.1 - 0.017 15.3 0.3 0.1 12.8 0.2 2.4 1 0 0 1 1 1 0 PHD domain of transcriptional enhancer, Asx PHD_2 PF13831.1 KKK25877.1 - 0.18 11.1 4.9 0.32 10.3 3.4 1.4 1 0 0 1 1 1 0 PHD-finger HisKA PF00512.20 KKK25877.1 - 0.39 10.7 2.1 5.8 6.9 0.1 2.5 2 0 0 2 2 2 0 His Kinase A (phospho-acceptor) domain FtsJ PF01728.14 KKK25879.1 - 4.9e-53 179.8 0.0 1.4e-50 171.8 0.0 2.1 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_18 PF12847.2 KKK25879.1 - 0.0069 16.9 0.0 0.014 15.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain 4HBT PF03061.17 KKK25880.1 - 2.4e-09 37.1 0.1 4.3e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily CDK2AP PF09806.4 KKK25880.1 - 0.038 14.2 7.1 0.065 13.4 1.8 2.2 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein DEAD PF00270.24 KKK25881.1 - 2.1e-41 141.2 0.0 7.1e-41 139.5 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KKK25881.1 - 2.9e-22 78.3 0.0 8.1e-22 76.8 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 KKK25881.1 - 0.0028 16.5 0.0 0.005 15.6 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain PMSI1 PF15322.1 KKK25881.1 - 0.11 11.5 1.8 0.21 10.6 1.3 1.4 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative Glypican PF01153.14 KKK25881.1 - 1.9 6.9 8.0 7.8 4.9 2.5 2.1 2 0 0 2 2 2 0 Glypican RNA_polI_A34 PF08208.6 KKK25881.1 - 9.1 5.9 21.6 0.13 11.8 8.8 2.2 2 0 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 LUC7 PF03194.10 KKK25882.1 - 1.6e-72 244.0 1.7 2e-72 243.7 1.2 1.0 1 0 0 1 1 1 1 LUC7 N_terminus MCPsignal PF00015.16 KKK25882.1 - 0.037 13.5 0.0 0.053 13.0 0.0 1.2 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain AAA_13 PF13166.1 KKK25882.1 - 0.068 11.6 1.1 0.09 11.2 0.3 1.5 1 1 0 1 1 1 0 AAA domain Snf7 PF03357.16 KKK25882.1 - 0.23 10.8 5.1 0.18 11.1 1.9 2.0 2 1 0 2 2 2 0 Snf7 Nucleo_P87 PF07267.6 KKK25883.1 - 5.8 5.4 15.4 7 5.1 10.7 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 FF PF01846.14 KKK25884.1 - 3.4e-14 52.5 6.8 2.7e-10 40.0 0.1 3.7 3 0 0 3 3 3 3 FF domain WW PF00397.21 KKK25884.1 - 6.6e-09 35.4 3.5 6.6e-09 35.4 2.4 3.1 3 0 0 3 3 3 1 WW domain DUF4200 PF13863.1 KKK25884.1 - 4.1 7.3 30.6 1.1 9.2 6.7 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4200) Proteasome PF00227.21 KKK25885.1 - 2.8e-61 206.1 0.2 3.4e-61 205.8 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 KKK25885.1 - 3.1e-14 51.9 0.2 7.1e-14 50.8 0.1 1.7 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature NAD_binding_10 PF13460.1 KKK25887.1 - 5.7e-11 42.7 0.7 6.8e-11 42.5 0.5 1.2 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 KKK25887.1 - 1.8e-05 24.1 0.4 0.00012 21.4 0.0 2.0 2 0 0 2 2 2 1 NmrA-like family Epimerase PF01370.16 KKK25887.1 - 8.5e-05 22.0 0.0 0.0008 18.9 0.0 2.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 KKK25887.1 - 0.00012 21.1 0.1 0.15 10.9 0.0 2.1 1 1 1 2 2 2 2 Male sterility protein Semialdhyde_dh PF01118.19 KKK25887.1 - 0.00025 21.3 0.1 0.0022 18.3 0.0 2.2 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain HIM1 PF08732.5 KKK25887.1 - 0.00062 18.3 0.0 0.00085 17.8 0.0 1.3 1 0 0 1 1 1 1 HIM1 DapB_N PF01113.15 KKK25887.1 - 0.044 13.6 0.0 0.22 11.4 0.0 2.0 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Tht1 PF04163.7 KKK25888.1 - 0.0017 16.8 9.0 0.0067 14.8 3.5 3.3 2 2 1 3 3 3 1 Tht1-like nuclear fusion protein Med2 PF11214.3 KKK25888.1 - 0.91 9.5 10.5 0.78 9.7 1.4 3.4 1 1 2 3 3 3 0 Mediator complex subunit 2 HrpA_pilin PF09589.5 KKK25888.1 - 5.4 7.4 10.3 0.72 10.2 2.5 2.6 3 0 0 3 3 3 0 HrpA pilus formation protein Ribosomal_L6 PF00347.18 KKK25889.1 - 8.4e-25 87.0 0.1 1e-13 51.5 0.0 2.9 3 0 0 3 3 3 2 Ribosomal protein L6 Inositol_P PF00459.20 KKK25890.1 - 3.5e-53 180.6 0.8 7.3e-53 179.5 0.6 1.4 1 1 0 1 1 1 1 Inositol monophosphatase family FAD_binding_1 PF00667.15 KKK25891.1 - 2.8e-62 210.0 0.0 5.1e-62 209.1 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 KKK25891.1 - 5e-11 43.1 0.0 1.4e-10 41.7 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain POR PF01558.13 KKK25891.1 - 9.1e-09 35.4 0.1 2.3e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase Transketolase_C PF02780.15 KKK25891.1 - 5.4e-05 23.1 0.2 0.00018 21.4 0.1 1.9 1 0 0 1 1 1 1 Transketolase, C-terminal domain Proteasome PF00227.21 KKK25895.1 - 2e-44 151.1 0.3 1.7e-34 118.7 0.0 2.0 2 0 0 2 2 2 2 Proteasome subunit WD40 PF00400.27 KKK25896.1 - 3.5e-59 194.6 20.2 3.3e-13 48.9 0.2 7.9 7 1 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 KKK25896.1 - 8.2e-09 35.4 0.0 0.0027 17.4 0.0 2.8 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 KKK25896.1 - 2e-07 29.5 1.7 0.34 8.9 0.1 4.5 2 2 3 5 5 5 4 Nucleoporin Nup120/160 PQQ_2 PF13360.1 KKK25896.1 - 0.0017 17.8 0.7 0.62 9.4 0.1 3.1 2 1 0 2 2 2 1 PQQ-like domain PD40 PF07676.7 KKK25896.1 - 0.0055 16.3 0.1 14 5.4 0.0 4.2 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat DUF3312 PF11768.3 KKK25896.1 - 0.18 10.0 0.0 0.37 8.9 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3312) Exo_endo_phos PF03372.18 KKK25897.1 - 1.2e-19 71.2 0.3 2.1e-19 70.4 0.2 1.4 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family Luciferase_cat PF10285.4 KKK25897.1 - 0.14 11.3 0.2 0.27 10.3 0.0 1.5 2 0 0 2 2 2 0 Luciferase catalytic domain 2TM PF13239.1 KKK25897.1 - 0.86 9.7 3.8 0.53 10.3 0.3 2.1 2 0 0 2 2 2 0 2TM domain RED_N PF07808.8 KKK25898.1 - 6e-06 25.6 1.4 6e-06 25.6 1.0 2.0 2 1 0 2 2 2 1 RED-like protein N-terminal region Glyco_hydro_cc PF11790.3 KKK25899.1 - 5e-63 212.7 1.3 5.7e-63 212.5 0.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Choline_transpo PF04515.7 KKK25899.1 - 0.06 12.0 0.3 0.082 11.6 0.2 1.1 1 0 0 1 1 1 0 Plasma-membrane choline transporter DUF3243 PF11588.3 KKK25899.1 - 0.077 12.9 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3243) MFS_1 PF07690.11 KKK25900.1 - 3e-34 118.2 25.8 3e-34 118.2 17.9 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily SWI-SNF_Ssr4 PF08549.5 KKK25901.1 - 4.5e-298 990.2 8.5 5.1e-298 990.0 5.9 1.0 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1750) Thi4 PF01946.12 KKK25902.1 - 2.9e-102 340.6 0.0 3.6e-102 340.3 0.0 1.1 1 0 0 1 1 1 1 Thi4 family DAO PF01266.19 KKK25902.1 - 1.4e-08 34.0 0.3 2.8e-08 33.0 0.2 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KKK25902.1 - 8.1e-06 25.7 0.2 5.3e-05 23.1 0.1 2.5 2 1 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 KKK25902.1 - 1.9e-05 23.7 0.3 3.7e-05 22.8 0.2 1.5 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_9 PF13454.1 KKK25902.1 - 0.00011 22.0 0.2 0.00036 20.3 0.0 2.0 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 KKK25902.1 - 0.001 19.2 0.1 0.0019 18.2 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KKK25902.1 - 0.002 18.0 0.0 0.0037 17.1 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KKK25902.1 - 0.0067 15.3 0.9 0.025 13.4 0.5 1.9 2 0 0 2 2 2 1 FAD binding domain FAD_binding_3 PF01494.14 KKK25902.1 - 0.029 13.4 0.0 0.042 12.9 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain FAD_oxidored PF12831.2 KKK25902.1 - 0.038 13.0 0.0 0.059 12.4 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Trp_halogenase PF04820.9 KKK25902.1 - 0.1 11.2 0.2 0.14 10.7 0.1 1.1 1 0 0 1 1 1 0 Tryptophan halogenase HI0933_like PF03486.9 KKK25902.1 - 0.19 10.1 0.5 0.29 9.5 0.3 1.2 1 0 0 1 1 1 0 HI0933-like protein Ppx-GppA PF02541.11 KKK25903.1 - 3.8e-43 147.7 0.0 5.5e-43 147.1 0.0 1.2 1 0 0 1 1 1 1 Ppx/GppA phosphatase family GDA1_CD39 PF01150.12 KKK25903.1 - 0.0041 15.6 0.0 0.0077 14.7 0.0 1.3 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Pil1 PF13805.1 KKK25904.1 - 4.2e-84 281.8 5.5 6.8e-84 281.2 3.8 1.3 1 0 0 1 1 1 1 Eisosome component PIL1 FAM92 PF06730.6 KKK25904.1 - 0.029 13.7 0.6 0.053 12.8 0.4 1.4 1 0 0 1 1 1 0 FAM92 protein DUF1018 PF06252.7 KKK25904.1 - 0.051 14.0 1.6 1.1 9.8 0.6 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1018) RCR PF12273.3 KKK25905.1 - 3.1e-28 98.9 10.6 5.1e-28 98.2 7.3 1.3 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red DUF2668 PF10873.3 KKK25905.1 - 0.0029 17.7 0.6 0.0029 17.7 0.4 1.7 1 1 0 2 2 2 1 Protein of unknown function (DUF2668) LysE PF01810.13 KKK25905.1 - 0.0046 16.2 0.2 0.0058 15.9 0.1 1.1 1 0 0 1 1 1 1 LysE type translocator Shisa PF13908.1 KKK25905.1 - 0.0058 16.8 0.0 0.0079 16.3 0.0 1.2 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Rhabdo_glycop PF00974.13 KKK25905.1 - 0.019 13.2 0.1 0.024 12.8 0.0 1.1 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein Acyl_transf_3 PF01757.17 KKK25905.1 - 0.041 12.7 1.1 0.052 12.3 0.8 1.1 1 0 0 1 1 1 0 Acyltransferase family DUF1183 PF06682.7 KKK25905.1 - 0.044 13.3 0.1 0.051 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) Cytochrom_B_N PF00033.14 KKK25905.1 - 0.059 12.7 0.0 0.089 12.1 0.0 1.2 1 0 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB Tetraspannin PF00335.15 KKK25905.1 - 0.088 12.0 0.2 0.12 11.6 0.1 1.2 1 0 0 1 1 1 0 Tetraspanin family DUF1180 PF06679.7 KKK25905.1 - 0.12 12.3 0.1 0.12 12.3 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) Hum_adeno_E3A PF05393.6 KKK25905.1 - 0.15 11.7 0.3 0.22 11.1 0.2 1.2 1 0 0 1 1 1 0 Human adenovirus early E3A glycoprotein DUF2839 PF10999.3 KKK25905.1 - 0.59 10.2 4.2 7.2 6.7 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2839) Arf PF00025.16 KKK25906.1 - 3.8e-42 143.4 0.0 4.2e-42 143.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 KKK25906.1 - 1.2e-18 67.0 0.0 1.3e-18 66.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KKK25906.1 - 2.3e-09 37.7 0.0 3.8e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 KKK25906.1 - 8.4e-07 28.9 0.0 1.5e-06 28.1 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 KKK25906.1 - 1.2e-06 27.8 0.0 1.4e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 KKK25906.1 - 3.4e-06 26.3 0.0 4e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 KKK25906.1 - 7.4e-05 22.2 0.0 0.00059 19.3 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain G-alpha PF00503.15 KKK25906.1 - 8.5e-05 21.4 0.1 0.00018 20.3 0.0 1.6 2 0 0 2 2 2 1 G-protein alpha subunit Dynamin_N PF00350.18 KKK25906.1 - 0.00068 19.4 0.0 0.013 15.3 0.1 2.1 1 1 1 2 2 2 1 Dynamin family FeoB_N PF02421.13 KKK25906.1 - 0.0091 15.2 0.3 0.088 12.0 0.0 2.2 2 1 0 2 2 2 1 Ferrous iron transport protein B Pkinase PF00069.20 KKK25907.1 - 1.8e-12 46.9 0.0 2.4e-12 46.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK25907.1 - 0.009 15.1 0.1 0.021 13.8 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase RNA_pol_Rpb2_6 PF00562.23 KKK25908.1 - 5.2e-118 394.1 0.0 7e-118 393.7 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 KKK25908.1 - 1.3e-29 102.6 0.0 2.4e-29 101.7 0.0 1.4 2 0 0 2 2 2 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 KKK25908.1 - 2.6e-26 92.2 0.0 4.3e-26 91.4 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpa2_4 PF06883.7 KKK25908.1 - 6e-25 86.9 0.0 1.6e-24 85.5 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_3 PF04565.11 KKK25908.1 - 7.8e-24 83.2 0.0 2.1e-23 81.8 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_7 PF04560.15 KKK25908.1 - 9.7e-15 54.6 0.0 3.9e-14 52.6 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_5 PF04567.12 KKK25908.1 - 0.012 15.5 0.0 0.028 14.3 0.0 1.6 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 5 zf-CCCH_2 PF14608.1 KKK25909.1 - 1.4e-07 31.2 60.3 0.00013 21.7 9.8 5.4 5 0 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type ABC2_membrane PF01061.19 KKK25910.1 - 1.2e-38 132.4 32.6 3e-22 78.8 4.1 4.1 3 1 0 4 4 4 3 ABC-2 type transporter PDR_CDR PF06422.7 KKK25910.1 - 2.1e-30 104.4 0.1 2.5e-28 97.7 0.0 2.6 2 0 0 2 2 2 1 CDR ABC transporter ABC_tran PF00005.22 KKK25910.1 - 4.2e-19 69.2 0.0 7.1e-19 68.4 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_25 PF13481.1 KKK25910.1 - 0.00059 19.3 0.1 0.0014 18.0 0.0 1.6 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 KKK25910.1 - 0.001 18.2 0.1 0.0051 16.0 0.1 1.9 1 1 1 2 2 2 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 KKK25910.1 - 0.011 15.8 0.1 0.044 13.9 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.1 KKK25910.1 - 0.017 14.6 0.2 0.046 13.2 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.1 KKK25910.1 - 0.048 13.6 0.1 0.09 12.7 0.1 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_21 PF13304.1 KKK25910.1 - 0.056 13.3 0.0 0.47 10.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain cobW PF02492.14 KKK25910.1 - 0.08 12.3 0.5 0.16 11.3 0.4 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.1 KKK25910.1 - 0.11 12.4 0.7 0.21 11.5 0.5 1.4 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 KKK25910.1 - 0.11 11.9 0.3 0.28 10.6 0.1 1.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.18 KKK25910.1 - 0.18 11.5 0.0 0.42 10.4 0.0 1.6 2 0 0 2 2 2 0 Dynamin family Mago-bind PF09282.5 KKK25911.1 - 1e-13 50.5 5.3 1.9e-13 49.6 3.7 1.5 1 0 0 1 1 1 1 Mago binding Amino_oxidase PF01593.19 KKK25912.1 - 2.8e-23 82.7 0.0 2.3e-22 79.7 0.0 1.9 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KKK25912.1 - 3.9e-14 52.4 0.0 1.4e-13 50.6 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KKK25912.1 - 1.1e-08 34.3 0.1 3.5e-06 26.1 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KKK25912.1 - 0.00065 18.6 0.0 0.0038 16.1 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.22 KKK25912.1 - 0.00082 19.7 0.0 0.19 12.1 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KKK25912.1 - 0.0021 17.2 0.1 0.0048 16.0 0.0 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 KKK25912.1 - 0.0027 16.8 0.0 0.0045 16.1 0.0 1.2 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.1 KKK25912.1 - 0.0053 16.5 0.1 0.024 14.4 0.0 2.0 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 KKK25912.1 - 0.018 14.9 0.1 0.083 12.7 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KKK25912.1 - 0.037 12.5 0.0 0.12 10.7 0.0 1.7 2 0 0 2 2 2 0 HI0933-like protein GMC_oxred_N PF00732.14 KKK25912.1 - 0.083 12.0 0.0 0.19 10.8 0.0 1.6 1 0 0 1 1 1 0 GMC oxidoreductase zf-UBR PF02207.15 KKK25913.1 - 5.3e-17 61.3 15.4 1.3e-16 60.0 10.7 1.7 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) zf-RING_2 PF13639.1 KKK25913.1 - 0.00014 21.6 1.0 0.00014 21.6 0.7 4.6 4 1 0 4 4 4 1 Ring finger domain ClpS PF02617.12 KKK25913.1 - 0.0085 15.7 0.0 0.023 14.4 0.0 1.7 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS UCR_UQCRX_QCR9 PF05365.7 KKK25914.1 - 1.5e-26 91.7 1.3 1.8e-26 91.4 0.9 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like Jacalin PF01419.12 KKK25924.1 - 0.00047 20.0 0.0 0.0008 19.3 0.0 1.4 1 0 0 1 1 1 1 Jacalin-like lectin domain DUF3533 PF12051.3 KKK25925.1 - 1.9e-95 319.8 8.4 2.8e-95 319.2 5.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) Bac_chlorC PF02043.12 KKK25925.1 - 0.12 12.2 0.2 3 7.6 0.0 2.5 2 0 0 2 2 2 0 Bacteriochlorophyll C binding protein Cu-oxidase_3 PF07732.10 KKK25926.1 - 3.9e-48 162.0 2.8 6.5e-47 158.1 0.1 3.4 3 1 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 KKK25926.1 - 1.8e-39 134.3 7.3 8.3e-37 125.7 0.7 3.7 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 KKK25926.1 - 6e-38 130.2 0.4 2.5e-37 128.2 0.1 2.2 2 0 0 2 2 2 1 Multicopper oxidase Phosphoesterase PF04185.9 KKK25927.1 - 1.5e-37 129.7 6.3 2.9e-37 128.7 4.3 1.4 1 0 0 1 1 1 1 Phosphoesterase family But2 PF09792.4 KKK25928.1 - 0.0028 17.4 1.4 0.0036 17.0 0.8 1.4 1 1 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain A_deaminase PF00962.17 KKK25929.1 - 7.8e-39 133.4 0.0 9.9e-38 129.8 0.0 2.0 1 1 0 1 1 1 1 Adenosine/AMP deaminase KdpA PF03814.10 KKK25929.1 - 0.053 11.5 0.0 0.076 11.0 0.0 1.1 1 0 0 1 1 1 0 Potassium-transporting ATPase A subunit Acetyltransf_13 PF13880.1 KKK25934.1 - 1.2e-30 105.0 0.0 2.9e-30 103.7 0.0 1.7 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.1 KKK25934.1 - 1.2e-17 63.1 0.4 2.2e-17 62.3 0.3 1.5 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO Lipase_GDSL_2 PF13472.1 KKK25936.1 - 2.1e-13 50.8 0.1 1.5e-11 44.7 0.0 2.3 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 KKK25936.1 - 6.2e-07 29.4 0.0 4.6e-06 26.6 0.0 2.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase ECH PF00378.15 KKK25936.1 - 0.11 11.5 0.0 0.47 9.5 0.0 1.9 2 0 0 2 2 2 0 Enoyl-CoA hydratase/isomerase family Glyco_hydro_18 PF00704.23 KKK25937.1 - 1.2e-17 64.4 0.0 2.3e-17 63.4 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 Fungal_trans PF04082.13 KKK25938.1 - 7.5e-11 41.3 1.3 1.5e-10 40.4 0.9 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK25938.1 - 3.1e-09 36.5 8.1 5e-09 35.9 5.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_U40 PF10464.4 KKK25938.1 - 0.04 13.3 0.0 0.075 12.4 0.0 1.4 1 0 0 1 1 1 0 Peptidase U40 UQ_con PF00179.21 KKK25939.1 - 7e-46 155.1 0.0 1.2e-45 154.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Acyl-CoA_dh_N PF02771.11 KKK25939.1 - 5.1e-23 81.7 0.1 9.7e-23 80.9 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.19 KKK25939.1 - 1.1e-22 80.8 0.1 1.7e-22 80.1 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 KKK25939.1 - 8.8e-16 57.1 0.0 1.9e-15 56.1 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 KKK25939.1 - 1.2e-08 35.3 0.3 2.1e-08 34.4 0.2 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Prok-E2_B PF14461.1 KKK25939.1 - 5.9e-05 22.8 0.0 0.00055 19.6 0.0 2.1 2 0 0 2 2 2 1 Prokaryotic E2 family B RWD PF05773.17 KKK25939.1 - 0.02 14.7 0.0 0.031 14.1 0.0 1.3 1 0 0 1 1 1 0 RWD domain Glyoxalase_2 PF12681.2 KKK25940.1 - 1.5e-08 35.2 0.0 3.2e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 KKK25940.1 - 0.0049 16.8 0.0 0.033 14.1 0.0 2.3 3 0 0 3 3 3 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Rick_17kDa_Anti PF05433.10 KKK25940.1 - 0.011 15.3 0.8 0.011 15.3 0.6 2.0 2 0 0 2 2 2 0 Glycine zipper 2TM domain Gly-zipper_OmpA PF13436.1 KKK25940.1 - 0.73 9.5 8.0 0.055 13.1 1.0 2.4 2 0 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain Gly-zipper_Omp PF13488.1 KKK25940.1 - 0.77 9.4 7.3 0.037 13.6 0.8 1.9 2 0 0 2 2 2 0 Glycine zipper EMG1 PF03587.9 KKK25941.1 - 2.4e-78 262.0 0.0 2.8e-78 261.8 0.0 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase PIP5K PF01504.13 KKK25942.1 - 6.2e-86 287.5 0.1 8.5e-86 287.1 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase CENP-R PF06729.7 KKK25942.1 - 0.046 13.3 1.3 0.076 12.6 0.0 1.9 2 0 0 2 2 2 0 Kinetochore component, CENP-R zf-CCHC_6 PF15288.1 KKK25942.1 - 0.16 11.6 1.2 0.37 10.4 0.8 1.5 1 0 0 1 1 1 0 Zinc knuckle XPG_N PF00752.12 KKK25943.1 - 8.5e-32 109.4 0.5 4.6e-31 107.0 0.0 2.3 2 0 0 2 2 2 1 XPG N-terminal domain XPG_I PF00867.13 KKK25943.1 - 3.9e-31 106.9 0.4 1e-30 105.6 0.0 1.9 2 0 0 2 2 2 1 XPG I-region 5_3_exonuc PF01367.15 KKK25943.1 - 0.00018 21.6 0.0 0.00018 21.6 0.0 2.4 3 0 0 3 3 3 1 5'-3' exonuclease, C-terminal SAM fold Linker_histone PF00538.14 KKK25944.1 - 9.9e-21 73.6 0.1 2.5e-20 72.3 0.1 1.7 1 0 0 1 1 1 1 linker histone H1 and H5 family TP53IP5 PF15331.1 KKK25944.1 - 4.7 7.0 12.6 5.7 6.7 8.7 1.3 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 MIP PF00230.15 KKK25945.1 - 8.2e-33 113.7 3.8 1.2e-32 113.2 2.6 1.2 1 0 0 1 1 1 1 Major intrinsic protein Fungal_trans_2 PF11951.3 KKK25945.1 - 6.6e-20 71.0 3.6 1.2e-19 70.2 2.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK25945.1 - 6.5e-08 32.3 8.9 1.3e-07 31.4 6.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CFEM PF05730.6 KKK25946.1 - 0.0041 16.9 12.1 0.026 14.3 8.4 2.2 1 1 0 1 1 1 1 CFEM domain BSP_II PF05432.6 KKK25948.1 - 1.1 8.4 7.0 2.1 7.5 4.9 1.4 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) ABC2_membrane PF01061.19 KKK25949.1 - 1e-83 279.6 47.9 1.1e-45 155.4 9.9 2.7 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 KKK25949.1 - 2e-38 131.8 0.0 1.4e-18 67.5 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 KKK25949.1 - 4.9e-30 103.2 3.8 2e-27 94.8 0.0 3.1 3 0 0 3 3 2 2 CDR ABC transporter AAA_25 PF13481.1 KKK25949.1 - 5.6e-07 29.1 0.2 0.0037 16.7 0.0 2.7 3 0 0 3 3 2 2 AAA domain ABC2_membrane_3 PF12698.2 KKK25949.1 - 9e-07 28.2 25.7 0.00012 21.2 6.3 2.7 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_22 PF13401.1 KKK25949.1 - 1.1e-05 25.6 0.1 0.05 13.7 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.1 KKK25949.1 - 5.5e-05 23.2 0.5 0.014 15.3 0.1 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.1 KKK25949.1 - 0.00056 20.2 0.1 1.8 8.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 KKK25949.1 - 0.00073 20.3 0.0 1.8 9.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain cobW PF02492.14 KKK25949.1 - 0.00096 18.6 1.1 0.37 10.2 0.2 2.3 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain ABC_trans_N PF14510.1 KKK25949.1 - 0.0016 18.4 0.0 0.0035 17.3 0.0 1.5 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal DUF258 PF03193.11 KKK25949.1 - 0.0016 17.6 0.1 0.0072 15.5 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 KKK25949.1 - 0.0017 17.8 0.4 0.075 12.5 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_28 PF13521.1 KKK25949.1 - 0.0018 18.2 1.5 0.52 10.2 0.4 2.4 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 KKK25949.1 - 0.006 16.4 0.1 1.5 8.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KKK25949.1 - 0.013 15.2 1.2 2.8 7.7 0.0 2.6 2 0 0 2 2 2 0 Part of AAA domain PduV-EutP PF10662.4 KKK25949.1 - 0.027 13.9 0.8 1.6 8.1 0.2 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NACHT PF05729.7 KKK25949.1 - 0.038 13.6 1.5 2.7 7.6 0.1 2.3 2 0 0 2 2 2 0 NACHT domain Miro PF08477.8 KKK25949.1 - 0.044 14.2 0.0 3.1 8.3 0.0 2.8 2 0 0 2 2 2 0 Miro-like protein AAA PF00004.24 KKK25949.1 - 0.066 13.4 0.1 14 5.9 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_21 PF13304.1 KKK25949.1 - 0.11 12.4 0.1 0.96 9.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 KKK25949.1 - 0.12 11.8 0.4 12 5.2 0.0 3.0 3 0 0 3 3 3 0 AAA-like domain DUF805 PF05656.9 KKK25949.1 - 0.17 11.7 10.0 2.1 8.1 1.6 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF805) UPF0079 PF02367.12 KKK25949.1 - 0.23 11.1 0.8 7.2 6.2 0.1 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Arch_ATPase PF01637.13 KKK25949.1 - 0.31 10.7 0.0 33 4.0 0.0 2.3 2 0 0 2 2 2 0 Archaeal ATPase Rhodanese PF00581.15 KKK25950.1 - 1.3e-16 60.8 0.0 4.6e-09 36.6 0.0 2.2 2 0 0 2 2 2 2 Rhodanese-like domain DUF202 PF02656.10 KKK25951.1 - 6.4e-20 71.1 0.3 1.6e-19 69.9 0.2 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF202) UCR_6-4kD PF08997.5 KKK25951.1 - 0.29 10.8 1.4 0.49 10.1 0.1 2.0 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase complex, 6.4kD protein Lactamase_B PF00753.22 KKK25952.1 - 3.9e-17 62.5 1.5 5.4e-17 62.0 1.1 1.1 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily SLAC1 PF03595.12 KKK25953.1 - 5.3e-104 347.4 54.9 6e-104 347.2 38.1 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel DUF2156 PF09924.4 KKK25955.1 - 4.1e-30 104.6 0.0 5.8e-30 104.1 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2156) Lipase_GDSL_2 PF13472.1 KKK25956.1 - 2.8e-12 47.1 0.1 4.4e-12 46.4 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 KKK25956.1 - 1.4e-11 44.6 0.3 2.9e-11 43.6 0.2 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.1 KKK25956.1 - 0.00059 19.6 0.0 0.2 11.3 0.0 2.2 1 1 1 2 2 2 2 GDSL-like Lipase/Acylhydrolase family DUF3018 PF11455.3 KKK25956.1 - 0.02 14.8 0.0 0.048 13.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3018) JSRP PF15312.1 KKK25956.1 - 0.12 12.3 0.5 0.27 11.2 0.4 1.5 1 0 0 1 1 1 0 Junctional sarcoplasmic reticulum protein Glyco_hydro_45 PF02015.11 KKK25957.1 - 7.3e-18 65.3 17.1 7.3e-18 65.3 11.8 2.5 1 1 1 2 2 2 1 Glycosyl hydrolase family 45 CBM_1 PF00734.13 KKK25957.1 - 2.8e-14 52.4 8.6 2.8e-14 52.4 6.0 2.6 3 0 0 3 3 3 1 Fungal cellulose binding domain DPBB_1 PF03330.13 KKK25957.1 - 4.6e-08 32.9 2.7 7.1e-08 32.3 0.3 2.5 2 0 0 2 2 2 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Corona_nucleoca PF00937.13 KKK25957.1 - 0.36 9.7 4.9 0.49 9.2 3.4 1.1 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Mucin PF01456.12 KKK25957.1 - 0.66 9.7 46.7 1.3 8.8 32.4 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Peptidase_S64 PF08192.6 KKK25957.1 - 3.3 5.9 8.0 4.1 5.6 5.5 1.0 1 0 0 1 1 1 0 Peptidase family S64 Herpes_BLLF1 PF05109.8 KKK25957.1 - 4.3 5.1 34.8 5.8 4.7 24.1 1.1 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) DUF572 PF04502.8 KKK25957.1 - 6.4 5.9 10.3 8.5 5.4 7.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Aa_trans PF01490.13 KKK25958.1 - 8.4e-21 73.9 34.9 1e-20 73.6 24.2 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF2633 PF11119.3 KKK25958.1 - 9 6.1 6.9 29 4.4 0.2 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2633) DUF3759 PF12585.3 KKK25959.1 - 2.3e-41 139.6 6.4 2.7e-41 139.3 4.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) Dabb PF07876.7 KKK25959.1 - 0.032 14.6 0.2 0.056 13.8 0.2 1.5 1 0 0 1 1 1 0 Stress responsive A/B Barrel Domain Herpes_Helicase PF02689.9 KKK25959.1 - 0.13 9.9 0.0 0.14 9.9 0.0 1.0 1 0 0 1 1 1 0 Helicase Glyco_tranf_2_3 PF13641.1 KKK25960.1 - 1e-31 110.5 0.0 2.1e-31 109.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 KKK25960.1 - 3.3e-18 66.0 0.1 3.3e-18 66.0 0.0 2.7 2 1 1 3 3 3 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.21 KKK25960.1 - 5.1e-12 45.7 0.0 7.6e-12 45.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 KKK25960.1 - 1.4e-06 27.7 0.0 2.6e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 21 FKBP_C PF00254.23 KKK25961.1 - 1.3e-33 114.8 0.0 1.5e-33 114.6 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase APH PF01636.18 KKK25962.1 - 9e-06 25.5 0.0 0.00013 21.8 0.0 2.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KKK25962.1 - 0.0035 16.9 0.0 0.0077 15.8 0.0 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase Zn_clus PF00172.13 KKK25963.1 - 4.6e-11 42.4 8.1 8.8e-11 41.5 5.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KKK25963.1 - 4.6e-11 42.0 0.7 1.2e-10 40.7 0.3 1.7 1 1 0 2 2 2 1 Fungal specific transcription factor domain DUF2853 PF11015.3 KKK25963.1 - 0.075 13.4 0.0 0.15 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2853) GTP_EFTU PF00009.22 KKK25981.1 - 8.3e-06 25.3 0.0 9.7e-06 25.1 0.0 1.0 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gly_transf_sug PF04488.10 KKK25983.1 - 2.1e-10 40.9 0.0 5.2e-10 39.6 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif DUF3989 PF13150.1 KKK25983.1 - 0.18 11.2 1.6 3.5 7.1 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3989) MIP PF00230.15 KKK26021.1 - 7.6e-54 182.5 5.3 1e-53 182.1 3.6 1.1 1 0 0 1 1 1 1 Major intrinsic protein ABC2_membrane PF01061.19 KKK26022.1 - 6.8e-30 103.7 7.9 9.6e-30 103.3 5.5 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 KKK26022.1 - 2.7e-18 66.5 0.0 5.6e-18 65.5 0.0 1.6 1 0 0 1 1 1 1 ABC transporter ABC_trans_N PF14510.1 KKK26022.1 - 0.0025 17.8 0.0 0.0055 16.7 0.0 1.7 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 KKK26022.1 - 0.051 12.9 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 KKK26022.1 - 0.059 13.0 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase AAA_33 PF13671.1 KKK26022.1 - 0.11 12.3 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain Peptidase_M28 PF04389.12 KKK26023.1 - 2.9e-35 121.5 0.0 5.1e-35 120.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 KKK26023.1 - 3.9e-16 58.6 0.0 8.3e-16 57.5 0.0 1.6 1 0 0 1 1 1 1 PA domain Peptidase_M42 PF05343.9 KKK26023.1 - 0.036 12.8 0.0 0.15 10.8 0.0 2.0 3 1 0 3 3 3 0 M42 glutamyl aminopeptidase FGGY_C PF02782.11 KKK26024.1 - 1.3e-74 250.0 0.2 2.5e-74 249.1 0.1 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 KKK26024.1 - 1.8e-68 230.4 0.0 2.4e-68 230.0 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain COesterase PF00135.23 KKK26045.1 - 1.9e-50 172.1 0.0 8e-50 170.0 0.0 1.8 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KKK26045.1 - 0.12 11.9 0.0 1 8.9 0.0 2.2 3 0 0 3 3 3 0 alpha/beta hydrolase fold Clathrin PF00637.15 KKK26047.1 - 1.8e-202 663.0 34.5 2.4e-33 114.7 1.9 7.7 7 0 0 7 7 7 7 Region in Clathrin and VPS Clathrin_propel PF01394.15 KKK26047.1 - 8e-35 116.7 1.5 1.5e-06 28.1 0.0 7.6 7 0 0 7 7 7 7 Clathrin propeller repeat Clathrin_H_link PF13838.1 KKK26047.1 - 5.9e-31 106.1 0.3 5.9e-31 106.1 0.2 2.6 3 0 0 3 3 3 1 Clathrin-H-link Coatomer_WDAD PF04053.9 KKK26047.1 - 0.0012 17.7 4.1 0.14 10.9 0.2 3.6 4 0 0 4 4 4 2 Coatomer WD associated region TPR_7 PF13176.1 KKK26047.1 - 0.0044 16.7 4.0 52 4.0 0.0 6.3 6 0 0 6 6 6 0 Tetratricopeptide repeat Vps39_1 PF10366.4 KKK26047.1 - 0.032 14.2 7.7 3.5 7.6 0.0 5.3 5 1 1 6 6 6 0 Vacuolar sorting protein 39 domain 1 TPR_14 PF13428.1 KKK26047.1 - 0.053 14.1 13.4 4.7 8.1 0.1 8.2 11 0 0 11 11 11 0 Tetratricopeptide repeat TPR_12 PF13424.1 KKK26047.1 - 0.11 12.4 7.0 4.5 7.2 0.0 5.6 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_19 PF14559.1 KKK26047.1 - 1.6 9.1 10.5 30 5.0 0.1 5.9 7 0 0 7 7 7 0 Tetratricopeptide repeat CPSase_L_D2 PF02786.12 KKK26048.1 - 2.5e-81 272.0 0.1 4e-81 271.3 0.1 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.13 KKK26048.1 - 1.2e-65 220.6 0.0 2e-65 219.8 0.0 1.4 1 0 0 1 1 1 1 Conserved carboxylase domain CPSase_L_chain PF00289.17 KKK26048.1 - 1.2e-35 121.9 0.0 2.5e-35 120.9 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 KKK26048.1 - 5.8e-30 103.4 0.0 1.9e-29 101.7 0.0 2.0 2 0 0 2 2 1 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.14 KKK26048.1 - 5.3e-27 94.9 0.0 1e-26 94.1 0.0 1.5 1 0 0 1 1 1 1 HMGL-like ATP-grasp_4 PF13535.1 KKK26048.1 - 5.6e-20 71.8 0.1 1.3e-19 70.6 0.1 1.6 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl PF00364.17 KKK26048.1 - 5.4e-19 67.6 2.8 5.4e-19 67.6 1.9 2.1 2 0 0 2 2 2 1 Biotin-requiring enzyme ATPgrasp_Ter PF15632.1 KKK26048.1 - 3.8e-16 58.7 0.0 1.7e-15 56.6 0.0 1.9 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 KKK26048.1 - 1.6e-10 40.7 0.0 3e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.1 KKK26048.1 - 4e-09 35.9 8.1 2e-06 27.3 0.2 3.4 3 1 1 4 4 4 2 Biotin-lipoyl like ATP-grasp PF02222.17 KKK26048.1 - 1.5e-07 30.9 0.0 2.9e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 KKK26048.1 - 3.8e-06 26.4 0.0 1.8e-05 24.3 0.0 2.0 1 1 0 1 1 1 1 RimK-like ATP-grasp domain HlyD_3 PF13437.1 KKK26048.1 - 1.1e-05 25.6 0.1 0.0027 18.0 0.1 3.5 2 1 1 3 3 3 1 HlyD family secretion protein HlyD PF00529.15 KKK26048.1 - 3.5e-05 23.2 0.2 0.002 17.4 0.1 2.5 2 0 0 2 2 2 1 HlyD family secretion protein HlyD_2 PF12700.2 KKK26048.1 - 3.7e-05 23.0 0.1 0.022 13.9 0.1 2.2 1 1 1 2 2 2 2 HlyD family secretion protein ATP-grasp_3 PF02655.9 KKK26048.1 - 5.5e-05 23.0 0.0 0.00014 21.7 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain DUF2118 PF09891.4 KKK26048.1 - 0.028 14.1 0.2 0.07 12.8 0.1 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2118) GCV_H PF01597.14 KKK26048.1 - 0.15 11.7 1.3 0.49 10.0 0.4 2.2 1 1 1 2 2 2 0 Glycine cleavage H-protein RnfC_N PF13375.1 KKK26048.1 - 0.17 11.6 2.7 1.7 8.3 1.9 2.5 1 1 0 1 1 1 0 RnfC Barrel sandwich hybrid domain HAD_2 PF13419.1 KKK26050.1 - 3.9e-15 56.5 0.0 1.5e-14 54.5 0.0 1.8 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KKK26050.1 - 1.4e-10 41.9 0.0 4.7e-08 33.7 0.0 2.1 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.2 KKK26050.1 - 7.5e-08 32.7 0.0 1.2e-07 32.0 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KKK26050.1 - 1.1e-07 31.4 0.1 2.1e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like PGP_phosphatase PF09419.5 KKK26050.1 - 0.0079 15.5 0.0 0.23 10.8 0.0 2.6 2 1 0 2 2 2 1 Mitochondrial PGP phosphatase Hydrolase_6 PF13344.1 KKK26050.1 - 0.058 13.2 0.0 0.18 11.7 0.0 1.8 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Smr PF01713.16 KKK26052.1 - 1.6e-10 40.9 0.1 3.1e-10 40.0 0.1 1.5 1 0 0 1 1 1 1 Smr domain DUF1771 PF08590.5 KKK26052.1 - 5.7e-10 39.0 9.0 1e-09 38.2 6.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) CUE PF02845.11 KKK26052.1 - 2.1e-07 30.2 0.0 4.7e-05 22.7 0.0 3.3 3 0 0 3 3 3 1 CUE domain GPI-anchored PF10342.4 KKK26053.1 - 3.6e-17 62.6 3.2 3.6e-17 62.6 2.2 1.9 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family LT-IIB PF06453.6 KKK26053.1 - 0.054 13.1 0.1 0.086 12.5 0.0 1.3 1 0 0 1 1 1 0 Type II heat-labile enterotoxin , B subunit (LT-IIB) WIF PF02019.13 KKK26053.1 - 0.067 12.6 0.0 0.11 11.9 0.0 1.4 1 1 0 1 1 1 0 WIF domain AvrE PF11725.3 KKK26053.1 - 0.073 10.0 1.4 0.099 9.6 0.9 1.1 1 0 0 1 1 1 0 Pathogenicity factor TRP PF06011.7 KKK26054.1 - 1.6e-163 544.4 27.5 2e-163 544.0 19.0 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 KKK26054.1 - 1.1e-43 148.6 0.7 2e-43 147.8 0.5 1.4 1 0 0 1 1 1 1 ML-like domain gpUL132 PF11359.3 KKK26054.1 - 4.5e-05 22.8 0.6 0.0015 17.9 0.0 2.8 3 0 0 3 3 3 1 Glycoprotein UL132 VirB3 PF05101.8 KKK26054.1 - 0.00027 20.8 6.3 0.044 13.7 0.0 3.6 3 0 0 3 3 3 2 Type IV secretory pathway, VirB3-like protein DUF843 PF05814.6 KKK26054.1 - 0.79 9.5 11.7 1.5 8.6 0.2 3.7 3 1 1 4 4 4 0 Baculovirus protein of unknown function (DUF843) Orbi_NS3 PF01616.11 KKK26054.1 - 1.7 7.5 4.5 1.1 8.2 0.0 2.8 3 0 0 3 3 3 0 Orbivirus NS3 DEAD PF00270.24 KKK26055.1 - 6.1e-44 149.4 0.0 1.4e-43 148.3 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF4217 PF13959.1 KKK26055.1 - 1.5e-21 75.6 0.1 2.9e-21 74.7 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 KKK26055.1 - 1.2e-20 73.1 0.0 2.8e-20 71.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Prothymosin PF03247.9 KKK26055.1 - 0.00068 19.7 31.7 0.0016 18.5 21.9 1.6 1 0 0 1 1 1 1 Prothymosin/parathymosin family Daxx PF03344.10 KKK26055.1 - 0.024 13.1 25.1 0.036 12.5 17.4 1.2 1 0 0 1 1 1 0 Daxx Family eIF-3c_N PF05470.7 KKK26055.1 - 0.16 10.0 11.0 0.22 9.5 7.6 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus DUF2457 PF10446.4 KKK26055.1 - 0.47 9.1 22.0 0.79 8.3 15.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF1510 PF07423.6 KKK26055.1 - 0.6 9.4 25.6 1 8.6 17.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Spore_coat_CotO PF14153.1 KKK26055.1 - 0.69 9.3 24.7 1.3 8.3 17.1 1.4 1 0 0 1 1 1 0 Spore coat protein CotO Nop14 PF04147.7 KKK26055.1 - 1.3 6.8 24.3 1.8 6.4 16.8 1.1 1 0 0 1 1 1 0 Nop14-like family Vfa1 PF08432.5 KKK26055.1 - 1.3 8.9 22.5 2.6 8.0 15.6 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 NOA36 PF06524.7 KKK26055.1 - 1.4 8.1 14.4 11 5.1 8.7 2.3 2 0 0 2 2 2 0 NOA36 protein DDHD PF02862.12 KKK26055.1 - 1.6 8.4 11.7 3.5 7.3 8.1 1.6 1 0 0 1 1 1 0 DDHD domain Paf1 PF03985.8 KKK26055.1 - 1.6 7.3 21.0 2.5 6.7 14.6 1.2 1 0 0 1 1 1 0 Paf1 Hid1 PF12722.2 KKK26055.1 - 2.1 5.9 10.8 2.9 5.4 7.5 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein BTV_NS2 PF04514.7 KKK26055.1 - 2.2 7.0 17.6 4.1 6.1 12.2 1.4 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Pilt PF15453.1 KKK26055.1 - 2.6 7.6 14.6 4.3 6.9 10.1 1.3 1 0 0 1 1 1 0 Protein incorporated later into Tight Junctions Na_trans_assoc PF06512.8 KKK26055.1 - 5.3 6.9 22.3 10 5.9 15.5 1.4 1 0 0 1 1 1 0 Sodium ion transport-associated TFIIF_alpha PF05793.7 KKK26055.1 - 6.5 4.9 30.8 10 4.3 21.3 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Pox_Ag35 PF03286.9 KKK26055.1 - 7 6.1 21.9 0.42 10.1 11.5 1.7 2 0 0 2 2 2 0 Pox virus Ag35 surface protein PPP4R2 PF09184.6 KKK26055.1 - 8.1 5.8 28.1 14 5.0 19.5 1.3 1 0 0 1 1 1 0 PPP4R2 Sars6 PF12133.3 KKK26059.1 - 0.14 11.8 0.0 0.38 10.4 0.0 1.7 1 0 0 1 1 1 0 Open reading frame 6 from SARS coronavirus NDUFA12 PF05071.11 KKK26060.1 - 2.4e-13 50.4 0.7 2.4e-13 50.4 0.5 1.9 1 1 1 2 2 2 1 NADH ubiquinone oxidoreductase subunit NDUFA12 Pyridoxal_deC PF00282.14 KKK26074.1 - 1.3e-70 237.7 0.0 1.7e-70 237.3 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain OKR_DC_1 PF01276.15 KKK26074.1 - 0.14 10.6 0.0 0.21 10.0 0.0 1.3 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain Phasin PF05597.6 KKK26075.1 - 0.13 12.0 0.5 0.3 10.8 0.3 1.6 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) NPV_P10 PF05531.7 KKK26075.1 - 0.14 12.4 0.2 0.36 11.1 0.1 1.7 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein MFS_1 PF07690.11 KKK26076.1 - 2.8e-30 105.2 41.5 4.8e-17 61.7 6.0 3.0 2 2 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KKK26076.1 - 4e-06 25.6 5.9 4e-06 25.6 4.1 3.2 3 0 0 3 3 3 2 Sugar (and other) transporter DUF4611 PF15387.1 KKK26077.1 - 0.47 10.6 2.7 2.2 8.4 1.9 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4611) ECM11 PF15463.1 KKK26077.1 - 0.5 10.6 6.0 0.55 10.5 3.2 1.8 1 1 0 1 1 1 0 Extracellular mutant protein 11 Glyco_hydro_71 PF03659.9 KKK26078.1 - 2.5e-158 526.6 6.3 2.5e-158 526.6 4.4 1.3 2 0 0 2 2 2 1 Glycosyl hydrolase family 71 DUF4434 PF14488.1 KKK26078.1 - 0.0089 15.7 1.3 0.38 10.4 0.3 3.0 1 1 1 2 2 2 1 Domain of unknown function (DUF4434) Glyco_transf_28 PF03033.15 KKK26079.1 - 1.2e-17 63.9 0.0 1.3e-16 60.5 0.0 2.3 1 1 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.13 KKK26079.1 - 6.8e-06 24.9 0.0 1.2e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase ATG_C PF09333.6 KKK26079.1 - 0.012 15.7 0.0 0.033 14.3 0.0 1.7 1 0 0 1 1 1 0 ATG C terminal domain Glyco_tran_28_C PF04101.11 KKK26079.1 - 0.013 15.2 0.0 0.029 14.0 0.0 1.6 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain Annexin PF00191.15 KKK26080.1 - 1.4e-49 165.8 0.8 2.3e-19 69.0 0.0 3.4 3 0 0 3 3 3 3 Annexin B56 PF01603.15 KKK26082.1 - 1.2e-173 577.4 8.5 1.5e-173 577.1 5.9 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Asparaginase_2 PF01112.13 KKK26088.1 - 2.8e-37 128.1 1.0 9.5e-21 73.8 0.0 2.1 2 0 0 2 2 2 2 Asparaginase DUF1940 PF09155.5 KKK26088.1 - 0.08 12.7 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1940) Actin PF00022.14 KKK26089.1 - 2.7e-89 299.3 0.0 6.2e-89 298.1 0.0 1.5 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.8 KKK26089.1 - 0.042 12.4 0.0 0.91 8.0 0.0 2.2 2 0 0 2 2 2 0 MreB/Mbl protein E1-E2_ATPase PF00122.15 KKK26114.1 - 3.4e-38 130.9 0.3 6.1e-38 130.1 0.2 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KKK26114.1 - 3.6e-33 114.6 10.9 3.6e-33 114.6 7.6 2.1 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KKK26114.1 - 1.6e-29 103.8 0.0 5.1e-29 102.2 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KKK26114.1 - 3.7e-16 58.8 0.0 8.8e-16 57.6 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 KKK26114.1 - 3e-13 50.3 0.0 9.6e-13 48.7 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KKK26114.1 - 0.00021 20.9 0.2 0.015 14.9 0.2 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase BATS PF06968.8 KKK26115.1 - 9e-29 99.1 0.0 6.8e-28 96.3 0.0 2.3 2 0 0 2 2 2 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.16 KKK26115.1 - 4.9e-16 59.3 0.0 2.9e-15 56.8 0.0 2.1 3 0 0 3 3 3 1 Radical SAM superfamily P33MONOX PF15302.1 KKK26115.1 - 0.024 14.2 0.0 0.059 12.9 0.0 1.6 1 0 0 1 1 1 0 P33 mono-oxygenase Aminotran_3 PF00202.16 KKK26116.1 - 6.9e-38 130.3 0.0 9.7e-21 73.9 0.0 2.4 2 1 0 2 2 2 2 Aminotransferase class-III AAA_26 PF13500.1 KKK26116.1 - 6.7e-37 127.0 0.0 1e-36 126.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain Aminotran_1_2 PF00155.16 KKK26117.1 - 4.6e-38 131.0 0.0 5.5e-38 130.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_3 PF00202.16 KKK26117.1 - 0.0014 17.5 0.0 0.0021 16.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-III Cys_Met_Meta_PP PF01053.15 KKK26117.1 - 0.0055 15.0 0.0 0.0071 14.6 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme OKR_DC_1 PF01276.15 KKK26117.1 - 0.022 13.2 0.0 0.064 11.7 0.0 1.6 1 1 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain Glyco_hydro_3 PF00933.16 KKK26118.1 - 1.2e-86 290.3 0.0 1.7e-86 289.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KKK26118.1 - 3.1e-42 144.6 0.1 1.5e-40 139.1 0.0 3.0 2 1 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Citrate_synt PF00285.16 KKK26119.1 - 5.2e-98 328.0 0.0 6.2e-98 327.8 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase ABC_tran PF00005.22 KKK26120.1 - 4.6e-47 159.7 0.0 1.3e-25 90.2 0.0 3.8 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 KKK26120.1 - 5.8e-15 56.0 1.4 0.004 17.1 0.0 4.2 3 1 1 4 4 4 4 AAA domain SMC_N PF02463.14 KKK26120.1 - 6.5e-11 41.8 0.2 0.0064 15.7 0.0 4.3 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain Miro PF08477.8 KKK26120.1 - 1e-06 29.2 0.0 0.0036 17.8 0.0 3.1 3 0 0 3 3 2 2 Miro-like protein SbcCD_C PF13558.1 KKK26120.1 - 1.9e-06 27.6 0.0 0.13 12.2 0.0 3.1 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.1 KKK26120.1 - 3.1e-06 26.6 2.1 0.069 12.6 0.2 2.8 3 0 0 3 3 2 2 P-loop containing region of AAA domain Chromo PF00385.19 KKK26120.1 - 3.7e-06 26.5 0.0 7e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain MMR_HSR1 PF01926.18 KKK26120.1 - 5.1e-06 26.4 0.0 0.048 13.6 0.0 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase DUF258 PF03193.11 KKK26120.1 - 5.2e-06 25.7 0.0 0.026 13.7 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_23 PF13476.1 KKK26120.1 - 6.4e-06 26.6 0.0 0.077 13.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 KKK26120.1 - 8.5e-06 25.9 0.0 0.026 14.6 0.0 3.0 2 1 0 2 2 2 2 AAA domain AAA_15 PF13175.1 KKK26120.1 - 8.6e-06 25.0 0.0 0.14 11.2 0.0 3.2 3 0 0 3 3 3 1 AAA ATPase domain AAA_10 PF12846.2 KKK26120.1 - 2.8e-05 23.6 1.2 1.1 8.5 0.0 4.1 4 1 0 4 4 4 2 AAA-like domain AAA_17 PF13207.1 KKK26120.1 - 4.3e-05 24.3 0.0 0.55 11.0 0.0 3.0 3 0 0 3 3 2 2 AAA domain DUF87 PF01935.12 KKK26120.1 - 0.00016 21.6 0.5 0.25 11.1 0.1 3.8 3 1 0 3 3 3 1 Domain of unknown function DUF87 NACHT PF05729.7 KKK26120.1 - 0.00016 21.3 0.4 0.1 12.2 0.0 2.8 2 0 0 2 2 2 1 NACHT domain AAA_13 PF13166.1 KKK26120.1 - 0.0004 18.9 0.0 0.024 13.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain Dynamin_N PF00350.18 KKK26120.1 - 0.0007 19.4 0.1 0.1 12.4 0.0 3.2 2 1 0 2 2 2 1 Dynamin family AAA_28 PF13521.1 KKK26120.1 - 0.001 19.0 0.0 0.14 12.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 KKK26120.1 - 0.0012 18.5 0.0 2.1 8.0 0.0 2.7 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 KKK26120.1 - 0.0013 18.5 0.0 2.5 7.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 KKK26120.1 - 0.0018 18.4 0.0 1 9.5 0.0 2.7 2 0 0 2 2 2 1 RNA helicase ArgK PF03308.11 KKK26120.1 - 0.016 14.0 0.2 4.3 6.0 0.1 2.4 2 0 0 2 2 2 0 ArgK protein AAA_25 PF13481.1 KKK26120.1 - 0.027 13.8 0.0 4.7 6.5 0.0 3.1 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 KKK26120.1 - 0.031 13.7 1.1 2.3 7.6 0.1 2.8 3 0 0 3 3 3 0 FtsK/SpoIIIE family PduV-EutP PF10662.4 KKK26120.1 - 0.056 12.9 0.1 6.2 6.3 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA PF00004.24 KKK26120.1 - 0.081 13.1 0.0 3.7 7.7 0.0 3.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.8 KKK26120.1 - 0.082 11.8 0.1 5.8 5.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_14 PF13173.1 KKK26120.1 - 0.093 12.6 0.0 10 6.0 0.0 2.7 2 0 0 2 2 2 0 AAA domain Septin PF00735.13 KKK26120.1 - 0.1 11.5 0.0 9.6 5.1 0.0 2.3 2 0 0 2 2 2 0 Septin zf-RING_2 PF13639.1 KKK26121.1 - 2.4e-08 33.6 2.8 5e-06 26.2 0.5 2.5 2 0 0 2 2 2 2 Ring finger domain zf-rbx1 PF12678.2 KKK26121.1 - 1.7e-06 28.0 0.5 3.8e-05 23.7 0.2 2.4 2 0 0 2 2 2 1 RING-H2 zinc finger zf-Apc11 PF12861.2 KKK26121.1 - 4e-05 23.3 1.9 0.00018 21.3 0.4 2.2 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger PHD PF00628.24 KKK26121.1 - 0.0062 16.2 1.1 0.015 14.9 0.8 1.7 1 0 0 1 1 1 1 PHD-finger zf-C3HC4_4 PF15227.1 KKK26121.1 - 0.027 14.3 2.4 0.027 14.3 1.6 2.3 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.3 KKK26121.1 - 0.036 14.0 4.8 0.25 11.3 1.5 2.5 2 1 0 2 2 2 0 FANCL C-terminal domain RINGv PF12906.2 KKK26121.1 - 0.046 13.7 2.4 0.046 13.7 1.7 1.8 2 0 0 2 2 2 0 RING-variant domain zf-C3HC4_2 PF13923.1 KKK26121.1 - 0.078 13.0 4.1 0.87 9.6 1.1 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KKK26121.1 - 0.078 12.7 0.5 0.078 12.7 0.4 2.4 3 0 0 3 3 2 0 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KKK26121.1 - 0.19 11.3 4.2 0.62 9.7 0.9 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) PHD_2 PF13831.1 KKK26121.1 - 0.54 9.6 3.0 1.4 8.3 2.1 1.7 1 1 0 1 1 1 0 PHD-finger zf-C3HC4 PF00097.20 KKK26121.1 - 0.62 9.7 9.9 0.11 12.2 1.0 2.5 3 0 0 3 3 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.6 KKK26121.1 - 1 9.4 5.3 0.15 12.0 0.9 1.7 2 0 0 2 2 2 0 RING-like domain zf-RING_4 PF14570.1 KKK26121.1 - 1.1 8.8 6.4 0.52 9.9 1.3 2.5 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain ANAPC15 PF15243.1 KKK26121.1 - 7.1 6.7 19.2 14 5.7 13.3 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 TRAP_alpha PF03896.11 KKK26121.1 - 7.5 5.4 9.3 10 4.9 6.4 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Amidoligase_2 PF12224.3 KKK26137.1 - 2.7e-08 33.7 0.0 2.9e-08 33.6 0.0 1.1 1 0 0 1 1 1 1 Putative amidoligase enzyme Pkinase PF00069.20 KKK26138.1 - 2.6e-34 118.5 0.0 1.8e-33 115.7 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK26138.1 - 3.6e-16 59.0 0.0 3.8e-14 52.4 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase DUF3128 PF11326.3 KKK26139.1 - 8.8e-31 105.8 2.3 1.5e-30 105.1 1.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) RNA12 PF10443.4 KKK26140.1 - 6.9e-169 561.9 0.0 9.4e-169 561.4 0.0 1.2 1 0 0 1 1 1 1 RNA12 protein p450 PF00067.17 KKK26140.1 - 3.4e-20 71.9 0.0 1.4e-19 70.0 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 Arch_ATPase PF01637.13 KKK26140.1 - 3e-05 23.8 0.0 8.4e-05 22.3 0.0 1.7 1 1 0 1 1 1 1 Archaeal ATPase RRM_1 PF00076.17 KKK26140.1 - 0.00014 21.4 0.0 0.00061 19.3 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KKK26140.1 - 0.00094 18.9 0.0 0.0021 17.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAA_16 PF13191.1 KKK26140.1 - 0.019 14.9 0.1 0.11 12.4 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain RRM_6 PF14259.1 KKK26140.1 - 0.15 12.0 0.0 0.38 10.7 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Peptidase_C14 PF00656.17 KKK26141.1 - 7.6e-05 22.5 0.0 0.0001 22.0 0.0 1.2 1 0 0 1 1 1 1 Caspase domain Raptor_N PF14538.1 KKK26141.1 - 0.00031 20.6 0.1 0.001 18.9 0.1 1.9 1 1 0 1 1 1 1 Raptor N-terminal CASPase like domain AIG2 PF06094.7 KKK26142.1 - 2.5e-07 31.1 0.0 3.4e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 AIG2-like family Apc15p PF05841.6 KKK26143.1 - 2.1e-26 93.1 1.9 5e-26 91.8 0.3 2.2 2 0 0 2 2 2 1 Apc15p protein GXGXG PF01493.14 KKK26144.1 - 4.6e-67 224.9 2.1 7.9e-67 224.1 1.4 1.3 1 0 0 1 1 1 1 GXGXG motif Fer4_20 PF14691.1 KKK26144.1 - 7.4e-23 80.2 0.1 1.3e-22 79.4 0.1 1.4 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox_2 PF07992.9 KKK26144.1 - 3e-19 69.6 0.0 9.1e-19 68.1 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KKK26144.1 - 1.9e-11 44.4 0.7 8.6e-05 22.6 0.1 2.5 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KKK26144.1 - 2.2e-09 37.1 0.1 8e-09 35.3 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KKK26144.1 - 9.9e-09 35.4 0.3 4.1e-05 23.9 0.1 3.2 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 KKK26144.1 - 1.7e-07 30.6 0.3 3e-07 29.9 0.2 1.4 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.19 KKK26144.1 - 7.5e-07 28.3 1.5 4.7e-05 22.4 0.3 2.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KKK26144.1 - 4.6e-06 25.7 0.4 0.00012 21.1 0.1 2.5 2 0 0 2 2 2 1 FAD binding domain NAD_binding_7 PF13241.1 KKK26144.1 - 2.7e-05 24.3 0.0 0.32 11.2 0.1 2.6 2 0 0 2 2 2 2 Putative NAD(P)-binding HI0933_like PF03486.9 KKK26144.1 - 3e-05 22.6 0.2 3e-05 22.6 0.1 1.8 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.2 KKK26144.1 - 4.3e-05 22.7 0.1 8.7e-05 21.7 0.1 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.16 KKK26144.1 - 6.2e-05 22.6 0.4 0.0065 16.0 0.1 2.3 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.14 KKK26144.1 - 0.00059 18.9 0.0 0.0015 17.6 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain DJ-1_PfpI PF01965.19 KKK26144.1 - 0.0016 17.9 0.0 0.0037 16.7 0.0 1.7 1 0 0 1 1 1 1 DJ-1/PfpI family Thi4 PF01946.12 KKK26144.1 - 0.0016 17.6 0.1 0.0037 16.3 0.1 1.5 1 0 0 1 1 1 1 Thi4 family Shikimate_DH PF01488.15 KKK26144.1 - 0.0092 16.0 0.3 4.7 7.3 0.0 2.9 3 1 0 3 3 2 1 Shikimate / quinate 5-dehydrogenase GIDA PF01134.17 KKK26144.1 - 0.01 14.7 2.1 0.023 13.5 0.1 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A FMO-like PF00743.14 KKK26144.1 - 0.01 14.1 0.0 0.65 8.1 0.0 2.2 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like ApbA PF02558.11 KKK26144.1 - 0.014 14.8 0.1 0.23 10.8 0.1 2.3 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA NAD_binding_9 PF13454.1 KKK26144.1 - 0.018 14.8 0.1 0.087 12.6 0.0 2.3 3 0 0 3 3 2 0 FAD-NAD(P)-binding F420_oxidored PF03807.12 KKK26144.1 - 0.019 15.3 0.1 0.46 10.9 0.1 2.6 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.18 KKK26144.1 - 0.021 14.5 0.0 0.045 13.4 0.0 1.6 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus YjeF_N PF03853.10 KKK26144.1 - 0.031 13.8 0.0 0.54 9.8 0.0 2.3 2 0 0 2 2 2 0 YjeF-related protein N-terminus NAD_binding_2 PF03446.10 KKK26144.1 - 0.035 13.9 0.1 0.088 12.6 0.0 1.7 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.14 KKK26144.1 - 0.061 12.4 0.1 0.25 10.4 0.0 1.9 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.16 KKK26144.1 - 0.11 12.3 2.4 11 5.8 0.0 2.9 3 0 0 3 3 3 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain IlvN PF07991.7 KKK26144.1 - 0.15 11.4 1.2 0.24 10.7 0.1 1.9 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain Lycopene_cycl PF05834.7 KKK26144.1 - 0.18 10.6 0.3 2.1 7.2 0.1 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein MADF_DNA_bdg PF10545.4 KKK26144.1 - 0.19 11.9 0.3 0.44 10.7 0.2 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like 3HCDH_N PF02737.13 KKK26144.1 - 0.63 9.6 3.2 0.34 10.5 0.1 2.0 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Glu_synthase PF01645.12 KKK26145.1 - 2.3e-149 497.3 0.0 3.4e-149 496.7 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase GATase_2 PF00310.16 KKK26145.1 - 6.2e-142 472.5 0.0 8.2e-142 472.1 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_syn_central PF04898.9 KKK26145.1 - 5.2e-120 400.0 0.0 8e-120 399.4 0.0 1.3 1 0 0 1 1 1 1 Glutamate synthase central domain FMN_dh PF01070.13 KKK26145.1 - 0.0076 15.1 0.9 0.017 14.0 0.6 1.4 1 0 0 1 1 1 1 FMN-dependent dehydrogenase LMBR1 PF04791.11 KKK26150.1 - 9.4e-30 103.6 2.8 1.4e-29 102.9 2.0 1.3 1 0 0 1 1 1 1 LMBR1-like membrane protein BAG PF02179.11 KKK26150.1 - 5.3e-13 48.8 0.0 1.3e-12 47.6 0.0 1.6 1 0 0 1 1 1 1 BAG domain FUSC PF04632.7 KKK26150.1 - 8.5e-05 21.1 9.5 0.00011 20.8 0.9 2.4 2 0 0 2 2 2 2 Fusaric acid resistance protein family ubiquitin PF00240.18 KKK26150.1 - 0.0011 18.3 0.0 0.0019 17.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family HemY_N PF07219.8 KKK26150.1 - 0.25 10.8 12.4 1 8.9 3.5 3.3 3 0 0 3 3 3 0 HemY protein N-terminus Chalcone PF02431.10 KKK26151.1 - 2.9e-67 225.9 0.0 3.7e-67 225.5 0.0 1.1 1 0 0 1 1 1 1 Chalcone-flavanone isomerase Glutaredoxin PF00462.19 KKK26152.1 - 5.7e-22 77.4 0.0 8e-22 77.0 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin DUF836 PF05768.9 KKK26152.1 - 0.0019 18.4 0.0 0.0023 18.1 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_2 PF13098.1 KKK26152.1 - 0.015 15.4 0.1 0.03 14.5 0.1 1.6 1 1 0 1 1 1 0 Thioredoxin-like domain TraF PF13728.1 KKK26152.1 - 0.015 14.7 0.0 0.016 14.6 0.0 1.2 1 0 0 1 1 1 0 F plasmid transfer operon protein Thioredoxin PF00085.15 KKK26152.1 - 0.017 14.7 0.0 0.018 14.7 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin GST_N_3 PF13417.1 KKK26152.1 - 0.047 13.9 0.0 0.068 13.3 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Thioredoxin_9 PF14595.1 KKK26152.1 - 0.049 13.1 0.0 0.051 13.1 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin DSBA PF01323.15 KKK26152.1 - 0.066 12.7 0.3 0.28 10.6 0.1 1.8 1 1 1 2 2 2 0 DSBA-like thioredoxin domain Thioredoxin_7 PF13899.1 KKK26152.1 - 0.11 12.4 0.0 0.21 11.6 0.0 1.5 1 1 0 1 1 1 0 Thioredoxin-like Thioredoxin_4 PF13462.1 KKK26152.1 - 0.14 12.1 0.4 1.3 9.0 0.1 2.0 1 1 1 2 2 2 0 Thioredoxin Thioredoxin_3 PF13192.1 KKK26152.1 - 0.15 11.9 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin domain Thioredoxin_8 PF13905.1 KKK26152.1 - 0.16 12.1 0.1 0.28 11.3 0.0 1.4 1 1 0 1 1 1 0 Thioredoxin-like Med15_fungi PF05397.7 KKK26153.1 - 3.9e-38 129.9 0.0 3.9e-38 129.9 0.0 6.0 7 0 0 7 7 7 1 Mediator complex subunit 15 zf-DHHC PF01529.15 KKK26153.1 - 2.5 7.4 5.4 9.2 5.6 3.7 2.0 1 0 0 1 1 1 0 DHHC palmitoyltransferase Plasmodium_Vir PF05795.6 KKK26153.1 - 3.2 6.8 4.0 13 4.9 2.8 2.0 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Nuc_sug_transp PF04142.10 KKK26154.1 - 2.8e-09 36.4 1.9 4.9e-09 35.6 1.3 1.3 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.6 KKK26154.1 - 5.4e-08 32.0 7.3 1e-07 31.2 5.1 1.3 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 KKK26154.1 - 7.8e-07 29.1 26.7 0.00019 21.4 4.8 3.1 3 1 0 3 3 3 2 EamA-like transporter family TPT PF03151.11 KKK26154.1 - 7.2e-05 22.4 16.3 0.024 14.2 0.1 2.6 3 0 0 3 3 3 2 Triose-phosphate Transporter family EmrE PF13536.1 KKK26154.1 - 0.002 18.3 7.1 0.002 18.3 4.9 3.4 2 1 1 3 3 3 1 Multidrug resistance efflux transporter Oxidored_q1_C PF01010.14 KKK26154.1 - 0.021 14.3 0.3 0.035 13.6 0.2 1.3 1 0 0 1 1 1 0 NADH-Ubiquinone oxidoreductase (complex I) subunit C-terminus PALP PF00291.20 KKK26157.1 - 5.8e-53 180.1 0.1 7.2e-53 179.7 0.1 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme ADH_zinc_N PF00107.21 KKK26157.1 - 0.049 13.1 0.2 0.27 10.7 0.0 2.4 3 0 0 3 3 3 0 Zinc-binding dehydrogenase KR PF08659.5 KKK26157.1 - 0.096 12.3 2.0 0.17 11.5 0.1 2.2 2 0 0 2 2 2 0 KR domain DAGK_cat PF00781.19 KKK26157.1 - 0.11 11.8 0.2 0.83 9.0 0.0 2.4 2 0 0 2 2 2 0 Diacylglycerol kinase catalytic domain GTP_EFTU_D3 PF03143.12 KKK26158.1 - 1.9e-36 124.1 0.2 6.7e-36 122.4 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 KKK26158.1 - 1.6e-16 60.1 1.6 3.7e-16 58.9 1.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 KKK26158.1 - 1.4e-05 24.5 0.3 3.5e-05 23.3 0.2 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 4 Semialdhyde_dhC PF02774.13 KKK26158.1 - 0.028 14.2 0.4 0.21 11.4 0.1 2.3 1 1 1 2 2 2 0 Semialdehyde dehydrogenase, dimerisation domain Ribosomal_S5 PF00333.15 KKK26158.1 - 0.06 13.0 1.8 0.16 11.7 0.0 2.3 2 0 0 2 2 2 0 Ribosomal protein S5, N-terminal domain TIP49 PF06068.8 KKK26159.1 - 3.1e-187 622.1 0.0 3.6e-187 621.9 0.0 1.0 1 0 0 1 1 1 1 TIP49 C-terminus RuvB_N PF05496.7 KKK26159.1 - 7.9e-12 44.7 0.4 4.7e-07 29.1 0.0 2.6 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA PF00004.24 KKK26159.1 - 4.3e-11 43.1 0.2 4.3e-07 30.1 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KKK26159.1 - 4.6e-06 26.7 0.0 0.01 15.8 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 KKK26159.1 - 1.6e-05 25.0 0.1 0.18 11.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 KKK26159.1 - 6.1e-05 22.6 0.1 0.00015 21.4 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_28 PF13521.1 KKK26159.1 - 0.00031 20.7 0.1 0.00069 19.6 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KKK26159.1 - 0.00071 19.3 0.2 0.16 11.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 KKK26159.1 - 0.0013 18.2 0.1 0.96 8.8 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain Zeta_toxin PF06414.7 KKK26159.1 - 0.0013 17.8 0.3 0.0031 16.6 0.2 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_25 PF13481.1 KKK26159.1 - 0.0026 17.2 0.0 0.0049 16.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 KKK26159.1 - 0.011 14.9 0.1 0.48 9.5 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 KKK26159.1 - 0.026 13.9 0.1 0.049 13.0 0.1 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF2075 PF09848.4 KKK26159.1 - 0.029 13.3 0.0 0.052 12.5 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_18 PF13238.1 KKK26159.1 - 0.044 14.0 0.1 0.23 11.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain KaiC PF06745.8 KKK26159.1 - 0.06 12.4 1.4 0.13 11.3 0.0 2.1 3 0 0 3 3 3 0 KaiC AAA_17 PF13207.1 KKK26159.1 - 0.065 14.0 0.1 0.17 12.7 0.0 1.9 1 1 0 1 1 1 0 AAA domain DnaB_C PF03796.10 KKK26159.1 - 0.095 11.5 0.0 0.18 10.6 0.0 1.4 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain NAD_binding_8 PF13450.1 KKK26160.1 - 2.5e-11 43.4 0.0 5.2e-11 42.4 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 KKK26160.1 - 6.4e-08 32.0 0.0 5.1e-07 29.1 0.0 2.0 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.1 KKK26160.1 - 0.00011 21.9 0.1 0.42 10.3 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding DAO PF01266.19 KKK26160.1 - 0.00021 20.3 0.6 0.00063 18.7 0.1 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KKK26160.1 - 0.0039 17.5 0.2 0.048 14.0 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KKK26160.1 - 0.035 14.1 0.0 0.11 12.5 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KKK26160.1 - 0.089 11.2 0.0 6.5 5.0 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein An_peroxidase PF03098.10 KKK26161.1 - 3.2e-99 332.7 0.0 6.2e-97 325.1 0.0 2.1 1 1 0 1 1 1 1 Animal haem peroxidase p450 PF00067.17 KKK26161.1 - 1.1e-09 37.3 0.0 9.7e-09 34.2 0.0 2.0 2 0 0 2 2 2 1 Cytochrome P450 Steroid_dh PF02544.11 KKK26162.1 - 2.6e-31 108.3 0.2 3.6e-31 107.9 0.1 1.2 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.7 KKK26162.1 - 6.6e-05 22.3 0.3 9.8e-05 21.7 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.8 KKK26162.1 - 0.0012 18.9 0.2 0.0028 17.7 0.2 1.7 1 0 0 1 1 1 1 Phospholipid methyltransferase Glyco_transf_34 PF05637.7 KKK26163.1 - 2.3e-62 210.6 0.0 2.9e-62 210.2 0.0 1.1 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Ribosomal_L28 PF00830.14 KKK26164.1 - 5.1e-20 71.0 1.1 1.1e-19 70.0 0.8 1.5 1 0 0 1 1 1 1 Ribosomal L28 family Bromodomain PF00439.20 KKK26165.1 - 4.2e-37 125.9 0.7 1.3e-18 66.6 0.1 2.7 2 0 0 2 2 2 2 Bromodomain Angiomotin_C PF12240.3 KKK26165.1 - 0.1 12.0 7.2 0.25 10.8 5.0 1.6 1 0 0 1 1 1 0 Angiomotin C terminal DUF3573 PF12097.3 KKK26165.1 - 0.98 7.9 4.6 1.6 7.2 3.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) HAUS4 PF14735.1 KKK26166.1 - 0.0033 16.7 1.3 0.013 14.8 0.9 1.9 1 1 0 1 1 1 1 HAUS augmin-like complex subunit 4 DinB_2 PF12867.2 KKK26166.1 - 0.16 12.3 8.4 0.77 10.1 0.4 2.9 2 1 1 3 3 3 0 DinB superfamily WD40 PF00400.27 KKK26167.1 - 1.2e-15 56.7 4.3 5.2e-07 29.3 0.0 5.8 6 0 0 6 6 6 4 WD domain, G-beta repeat EMP70 PF02990.11 KKK26167.1 - 0.16 10.4 0.0 0.23 9.8 0.0 1.1 1 0 0 1 1 1 0 Endomembrane protein 70 Utp12 PF04003.7 KKK26168.1 - 8.2e-21 73.9 0.0 1.4e-20 73.2 0.0 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family AKAP7_NLS PF10469.4 KKK26169.1 - 6.1e-15 55.4 0.0 1.2e-13 51.2 0.0 2.4 1 1 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain Sec6 PF06046.8 KKK26170.1 - 7.2e-168 559.1 3.5 7.2e-168 559.1 2.4 1.6 2 0 0 2 2 2 1 Exocyst complex component Sec6 Vps53_N PF04100.7 KKK26170.1 - 0.0014 17.4 10.7 0.0042 15.9 1.8 2.3 2 0 0 2 2 2 2 Vps53-like, N-terminal Cortex-I_coil PF09304.5 KKK26170.1 - 0.24 11.4 7.2 0.41 10.7 3.7 2.3 1 1 1 2 2 2 0 Cortexillin I, coiled coil NPV_P10 PF05531.7 KKK26170.1 - 0.44 10.8 3.5 10 6.4 0.9 3.0 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF572 PF04502.8 KKK26170.1 - 4.7 6.3 7.0 7.8 5.6 4.8 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) zf-CSL PF05207.8 KKK26171.1 - 3.2e-25 87.3 0.6 3.8e-25 87.1 0.4 1.1 1 0 0 1 1 1 1 CSL zinc finger Zn-ribbon_8 PF09723.5 KKK26171.1 - 0.012 15.5 0.2 0.021 14.7 0.2 1.4 1 0 0 1 1 1 0 Zinc ribbon domain Prok-RING_1 PF14446.1 KKK26171.1 - 1 9.1 4.1 3.2 7.5 2.9 1.8 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 Frataxin_Cyay PF01491.11 KKK26172.1 - 4.5e-35 119.7 0.0 5.8e-35 119.3 0.0 1.1 1 0 0 1 1 1 1 Frataxin-like domain GKAP PF03359.8 KKK26172.1 - 0.073 12.6 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 Guanylate-kinase-associated protein (GKAP) protein Pyridoxal_deC PF00282.14 KKK26173.1 - 8.8e-15 54.0 0.0 1e-08 34.0 0.0 2.2 1 1 1 2 2 2 2 Pyridoxal-dependent decarboxylase conserved domain Aminotran_1_2 PF00155.16 KKK26173.1 - 0.12 11.3 0.0 0.19 10.6 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II HMGL-like PF00682.14 KKK26174.1 - 3e-71 239.8 0.4 4.4e-71 239.2 0.3 1.2 1 0 0 1 1 1 1 HMGL-like PPTA PF01239.17 KKK26175.1 - 1.7e-36 122.0 15.4 1.4e-08 33.7 0.0 5.7 5 1 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat NRDE-2 PF08424.5 KKK26175.1 - 0.001 18.0 2.5 0.28 10.0 0.2 2.3 2 0 0 2 2 2 2 NRDE-2, necessary for RNA interference MIase PF02426.11 KKK26175.1 - 0.065 13.0 0.0 0.2 11.5 0.0 1.8 1 0 0 1 1 1 0 Muconolactone delta-isomerase RabGAP-TBC PF00566.13 KKK26176.1 - 1.7e-52 178.0 0.1 8.1e-52 175.7 0.0 2.1 1 1 0 1 1 1 1 Rab-GTPase-TBC domain Med9 PF07544.8 KKK26176.1 - 4.4 7.1 12.3 0.45 10.2 0.4 3.7 2 1 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 DUF1741 PF08427.5 KKK26177.1 - 7e-93 310.4 2.0 3.9e-92 307.9 0.0 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF1741) UPF0118 PF01594.11 KKK26177.1 - 0.048 12.6 1.3 0.1 11.6 0.9 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF20 Fe-S_biosyn PF01521.15 KKK26178.1 - 1.4e-19 70.0 0.0 1.9e-19 69.6 0.0 1.2 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis DUF2407_C PF13373.1 KKK26179.1 - 4.7e-42 143.2 0.1 4.7e-42 143.2 0.1 1.5 2 0 0 2 2 2 1 DUF2407 C-terminal domain DUF2407 PF10302.4 KKK26179.1 - 1.8e-32 111.3 0.1 4.4e-32 110.1 0.0 1.6 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.18 KKK26179.1 - 5.5e-05 22.4 0.0 9.9e-05 21.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family V-SNARE PF05008.10 KKK26180.1 - 6.8e-22 77.4 6.8 6.8e-22 77.4 4.7 1.8 2 0 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.3 KKK26180.1 - 1.9e-18 66.2 3.7 1.9e-18 66.2 2.6 2.8 3 1 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus DUF1848 PF08902.6 KKK26180.1 - 0.095 12.2 0.1 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1848) DUF1978 PF09321.5 KKK26180.1 - 0.1 12.0 8.1 0.13 11.6 5.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1978) TBCA PF02970.11 KKK26180.1 - 0.21 11.6 7.6 4.2 7.5 0.2 2.9 2 1 1 3 3 3 0 Tubulin binding cofactor A H-kinase_dim PF02895.9 KKK26180.1 - 0.36 11.1 7.8 3.2 8.1 1.6 2.5 2 0 0 2 2 2 0 Signal transducing histidine kinase, homodimeric domain Mer2 PF09074.5 KKK26180.1 - 1.3 8.9 7.9 7.2 6.4 5.4 2.0 1 1 0 1 1 1 0 Mer2 zf-C4H2 PF10146.4 KKK26180.1 - 3.5 7.5 6.4 0.69 9.8 0.8 1.9 1 1 0 2 2 2 0 Zinc finger-containing protein Spc7 PF08317.6 KKK26180.1 - 4 6.0 11.1 1.8 7.1 4.3 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein V_ATPase_I PF01496.14 KKK26180.1 - 4.9 4.8 6.9 8.2 4.1 4.8 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Dabb PF07876.7 KKK26181.1 - 2.9e-12 46.8 0.0 3.2e-12 46.7 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Ribosomal_S4e PF00900.15 KKK26181.1 - 0.031 13.9 0.0 0.038 13.6 0.0 1.3 1 0 0 1 1 1 0 Ribosomal family S4e Ctf8 PF09696.5 KKK26182.1 - 5.3e-21 74.6 0.0 6.2e-21 74.4 0.0 1.1 1 0 0 1 1 1 1 Ctf8 Cnl2_NKP2 PF09447.5 KKK26183.1 - 1.4e-27 95.1 1.3 1.4e-27 95.1 0.9 1.6 2 0 0 2 2 2 1 Cnl2/NKP2 family protein CPDase PF07823.6 KKK26183.1 - 0.075 12.5 0.1 0.18 11.2 0.0 1.5 1 1 0 1 1 1 0 Cyclic phosphodiesterase-like protein MRG PF05712.8 KKK26184.1 - 1.5e-56 190.3 0.1 2.3e-56 189.7 0.1 1.2 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.3 KKK26184.1 - 7.6e-10 38.3 4.4 1.1e-09 37.7 2.3 1.9 2 0 0 2 2 2 1 RNA binding activity-knot of a chromodomain Chromo PF00385.19 KKK26184.1 - 0.00079 19.0 1.4 0.003 17.2 1.0 2.0 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain PWWP PF00855.12 KKK26184.1 - 0.011 15.9 0.1 0.031 14.4 0.1 1.7 1 0 0 1 1 1 0 PWWP domain Aminotran_1_2 PF00155.16 KKK26185.1 - 2.1e-91 306.6 0.0 2.4e-91 306.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II APH PF01636.18 KKK26186.1 - 2.3e-05 24.2 0.0 2.8e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF155 PF02582.9 KKK26187.1 - 1.1e-58 198.0 0.0 1.6e-58 197.5 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 DUF4448 PF14610.1 KKK26190.1 - 1.2e-40 139.0 0.0 2.1e-40 138.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) SART-1 PF03343.8 KKK26191.1 - 4.2e-189 629.8 61.2 4.8e-189 629.6 42.4 1.0 1 0 0 1 1 1 1 SART-1 family PTH2 PF01981.11 KKK26192.1 - 6.2e-43 145.1 0.4 9.7e-43 144.5 0.3 1.3 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 BSP_II PF05432.6 KKK26192.1 - 0.00092 18.5 4.1 0.0012 18.1 2.8 1.1 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) Myc_N PF01056.13 KKK26192.1 - 0.8 8.8 4.2 1.1 8.4 2.9 1.2 1 0 0 1 1 1 0 Myc amino-terminal region RRM_1 PF00076.17 KKK26193.1 - 1e-45 153.1 0.0 7.5e-17 60.7 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KKK26193.1 - 2.6e-27 94.5 0.0 1.8e-09 37.4 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KKK26193.1 - 9.9e-23 79.7 0.0 2.5e-08 33.6 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KKK26193.1 - 8.5e-06 25.5 0.0 9.3e-05 22.2 0.0 2.4 3 0 0 3 3 3 1 RNA binding motif Nup35_RRM_2 PF14605.1 KKK26193.1 - 0.0001 22.0 0.0 0.0081 15.9 0.0 3.0 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif TPR_11 PF13414.1 KKK26194.1 - 5.7e-28 96.3 17.9 2.1e-07 30.4 0.0 8.0 6 2 1 8 8 8 6 TPR repeat TPR_1 PF00515.23 KKK26194.1 - 2.5e-27 93.3 4.4 0.00038 19.9 0.2 9.9 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_2 PF07719.12 KKK26194.1 - 4.4e-26 88.6 16.2 0.0035 17.1 0.2 10.6 11 0 0 11 11 10 7 Tetratricopeptide repeat Apc3 PF12895.2 KKK26194.1 - 1.1e-23 83.1 16.2 9.8e-20 70.4 0.5 6.0 6 0 0 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 KKK26194.1 - 4.4e-17 62.1 13.5 1e-05 25.7 0.1 7.4 6 2 2 8 8 7 4 Tetratricopeptide repeat TPR_12 PF13424.1 KKK26194.1 - 3e-16 59.1 25.1 5.4e-09 35.8 0.1 8.9 8 2 0 9 9 9 3 Tetratricopeptide repeat TPR_16 PF13432.1 KKK26194.1 - 3.4e-16 59.4 25.8 6.4e-05 23.5 0.3 8.8 7 2 2 9 9 9 6 Tetratricopeptide repeat TPR_14 PF13428.1 KKK26194.1 - 4.8e-15 54.7 18.0 0.23 12.2 0.2 10.3 7 2 3 10 10 10 2 Tetratricopeptide repeat TPR_8 PF13181.1 KKK26194.1 - 3.7e-14 51.3 0.0 0.05 13.3 0.0 8.1 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_17 PF13431.1 KKK26194.1 - 1.7e-09 37.0 1.5 0.29 11.4 0.0 8.2 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_10 PF13374.1 KKK26194.1 - 2e-08 33.9 18.4 0.0047 16.8 0.1 7.9 10 0 0 10 10 8 2 Tetratricopeptide repeat TPR_7 PF13176.1 KKK26194.1 - 1.6e-07 30.5 18.2 1.5 8.7 0.0 8.5 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_6 PF13174.1 KKK26194.1 - 3.6e-07 30.2 7.2 1.8 9.1 0.1 7.6 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_4 PF07721.9 KKK26194.1 - 0.00036 20.6 25.0 0.02 15.2 0.1 8.4 9 0 0 9 9 8 2 Tetratricopeptide repeat RPN7 PF10602.4 KKK26194.1 - 0.1 11.9 0.0 36 3.6 0.0 3.7 3 1 1 4 4 4 0 26S proteasome subunit RPN7 TPR_21 PF09976.4 KKK26194.1 - 0.14 12.1 5.7 39 4.1 0.0 5.5 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_9 PF13371.1 KKK26194.1 - 0.66 9.8 19.5 17 5.3 0.1 6.2 6 2 1 7 7 7 0 Tetratricopeptide repeat FAT PF02259.18 KKK26195.1 - 2.1e-72 244.0 10.3 4.2e-72 243.0 7.1 1.6 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.22 KKK26195.1 - 1.8e-30 106.1 0.4 5.8e-30 104.4 0.1 2.1 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 KKK26195.1 - 3.8e-08 32.6 0.1 1.1e-07 31.1 0.1 1.9 1 0 0 1 1 1 1 FATC domain DUF572 PF04502.8 KKK26196.1 - 2.4e-72 243.9 19.0 2.9e-72 243.6 13.2 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF572) zf-FCS PF06467.9 KKK26196.1 - 0.17 11.5 1.4 0.81 9.3 0.2 2.2 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif AXH PF08517.7 KKK26196.1 - 2.1 8.5 3.9 1 9.5 0.4 2.0 2 0 0 2 2 2 0 Ataxin-1 and HBP1 module (AXH) Gln-synt_C PF00120.19 KKK26197.1 - 1.7e-58 197.8 0.0 2e-58 197.5 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.14 KKK26197.1 - 3.2e-20 71.4 0.0 5.5e-20 70.7 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain MFS_1 PF07690.11 KKK26198.1 - 2.9e-33 115.0 25.2 4.9e-31 107.7 15.5 2.6 1 1 0 2 2 2 2 Major Facilitator Superfamily UNC-93 PF05978.11 KKK26198.1 - 0.0068 15.9 2.4 0.014 14.9 1.7 1.5 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 Pex14_N PF04695.8 KKK26198.1 - 0.01 15.8 0.6 0.23 11.4 0.1 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF846 PF05832.7 KKK26199.1 - 1.5e-48 164.1 9.9 1.8e-48 163.8 6.9 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) zf-CCHC PF00098.18 KKK26200.1 - 9.9e-42 138.9 82.8 1.1e-06 28.2 3.0 10.3 10 0 0 10 10 10 9 Zinc knuckle zf-CCHC_3 PF13917.1 KKK26200.1 - 7e-12 44.8 58.8 0.02 14.5 1.1 9.5 3 3 5 8 8 8 8 Zinc knuckle zf-CCHC_4 PF14392.1 KKK26200.1 - 5.1e-10 38.8 66.6 0.054 13.1 0.1 10.3 10 0 0 10 10 10 8 Zinc knuckle zf-CCHC_2 PF13696.1 KKK26200.1 - 0.00017 20.9 32.1 0.0093 15.4 0.1 7.1 6 1 1 7 7 7 3 Zinc knuckle zf-CCHC_6 PF15288.1 KKK26200.1 - 0.014 15.0 5.0 0.054 13.1 0.7 9.1 9 2 2 11 11 11 0 Zinc knuckle SelR PF01641.13 KKK26200.1 - 2 8.1 11.2 0.17 11.5 1.4 3.3 3 1 1 4 4 4 0 SelR domain HpcH_HpaI PF03328.9 KKK26201.1 - 3.4e-37 127.4 0.0 1.9e-36 125.0 0.0 1.9 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.1 KKK26201.1 - 1.3e-12 47.2 0.0 1.5e-06 27.2 0.0 2.1 2 0 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold Amino_oxidase PF01593.19 KKK26202.1 - 6.5e-83 279.2 0.0 3.3e-82 276.9 0.0 2.2 2 1 0 2 2 2 1 Flavin containing amine oxidoreductase SWIRM PF04433.12 KKK26202.1 - 3.1e-14 52.8 0.0 5.6e-14 52.0 0.0 1.5 1 0 0 1 1 1 1 SWIRM domain NAD_binding_8 PF13450.1 KKK26202.1 - 6.2e-07 29.3 0.1 1.5e-06 28.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HMG_box PF00505.14 KKK26202.1 - 0.00099 19.3 0.6 0.00099 19.3 0.4 2.9 1 1 1 2 2 2 1 HMG (high mobility group) box DAO PF01266.19 KKK26202.1 - 0.0097 14.8 0.0 0.096 11.5 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase HMG_box_2 PF09011.5 KKK26202.1 - 0.01 16.2 0.7 0.01 16.2 0.5 2.2 1 1 1 2 2 2 1 HMG-box domain SNARE_assoc PF09335.6 KKK26203.1 - 9.8e-11 41.9 3.3 9.8e-11 41.9 2.3 2.7 2 1 1 3 3 3 1 SNARE associated Golgi protein TMEMspv1-c74-12 PF11044.3 KKK26203.1 - 0.006 16.1 0.1 0.017 14.6 0.1 1.8 1 0 0 1 1 1 1 Plectrovirus spv1-c74 ORF 12 transmembrane protein DUF3186 PF11382.3 KKK26203.1 - 0.19 10.8 0.0 0.27 10.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3186) Pox_RNA_Pol_19 PF05320.7 KKK26203.1 - 1.1 8.9 5.8 58 3.3 5.2 2.1 2 0 0 2 2 2 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit DUF3671 PF12420.3 KKK26203.1 - 3.2 7.7 4.9 2.1 8.3 1.3 2.1 1 1 1 2 2 2 0 Protein of unknown function Patched PF02460.13 KKK26203.1 - 4.7 4.9 6.0 0.23 9.3 0.5 1.5 2 0 0 2 2 2 0 Patched family PhoD PF09423.5 KKK26204.1 - 5.6e-05 21.8 0.0 0.018 13.6 0.0 2.2 2 0 0 2 2 2 2 PhoD-like phosphatase Pyr_redox_2 PF07992.9 KKK26205.1 - 1.7e-25 90.1 0.1 2.1e-25 89.7 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KKK26205.1 - 1.2e-15 57.6 0.0 1.3e-12 47.9 0.0 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KKK26205.1 - 3.4e-10 40.3 0.0 4.2e-05 23.7 0.0 3.1 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KKK26205.1 - 0.00019 20.6 0.1 0.00063 18.9 0.0 1.8 2 0 0 2 2 2 1 Thi4 family NAD_binding_7 PF13241.1 KKK26205.1 - 0.00051 20.2 0.0 0.09 13.0 0.0 2.6 2 1 0 2 2 2 1 Putative NAD(P)-binding NAD_binding_8 PF13450.1 KKK26205.1 - 0.00082 19.3 0.5 0.03 14.3 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.15 KKK26205.1 - 0.0019 18.2 0.0 3.1 7.8 0.0 2.4 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase K_oxygenase PF13434.1 KKK26205.1 - 0.0041 16.0 0.0 0.89 8.4 0.0 3.0 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) GIDA PF01134.17 KKK26205.1 - 0.0087 14.9 3.1 1.5 7.5 0.0 3.5 4 1 1 5 5 5 1 Glucose inhibited division protein A DAO PF01266.19 KKK26205.1 - 0.016 14.1 5.1 1.8 7.4 0.0 3.8 2 2 2 4 4 4 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 KKK26205.1 - 0.037 13.0 0.6 4.5 6.2 0.0 2.4 2 1 0 2 2 2 0 FAD binding domain FAD_binding_2 PF00890.19 KKK26205.1 - 0.22 10.3 3.7 0.24 10.1 0.2 2.6 3 1 1 4 4 4 0 FAD binding domain Trp_halogenase PF04820.9 KKK26205.1 - 0.22 10.0 0.2 0.53 8.8 0.0 1.6 2 0 0 2 2 2 0 Tryptophan halogenase DHDPS PF00701.17 KKK26206.1 - 0.1 11.1 0.0 0.17 10.4 0.0 1.4 1 1 0 1 1 1 0 Dihydrodipicolinate synthetase family Sugar_tr PF00083.19 KKK26207.1 - 2.5e-102 342.7 27.8 2.9e-102 342.5 19.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KKK26207.1 - 2.3e-16 59.4 31.8 3e-10 39.3 2.6 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily OATP PF03137.15 KKK26207.1 - 1.4e-05 23.3 5.4 0.0032 15.6 0.2 2.4 2 0 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family DUF1228 PF06779.9 KKK26207.1 - 0.0096 15.9 3.2 0.098 12.6 0.7 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1228) DUF1771 PF08590.5 KKK26208.1 - 6.2e-17 61.3 10.2 1.6e-16 60.0 7.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Smr PF01713.16 KKK26208.1 - 1.7e-13 50.5 0.9 1.8e-12 47.2 0.1 3.0 3 0 0 3 3 3 1 Smr domain zf-CCCH PF00642.19 KKK26208.1 - 1.1e-06 28.1 3.0 0.0046 16.6 0.0 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) MoCF_biosynth PF00994.19 KKK26209.1 - 6.3e-25 87.2 0.0 1.4e-23 82.8 0.0 2.3 1 1 0 1 1 1 1 Probable molybdopterin binding domain Med26 PF08711.6 KKK26210.1 - 0.0013 18.1 0.3 0.0022 17.4 0.2 1.4 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Fungal_trans_2 PF11951.3 KKK26211.1 - 0.038 12.5 0.0 0.06 11.9 0.0 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain Mito_carr PF00153.22 KKK26212.1 - 2.4e-46 155.3 2.6 1.6e-15 56.5 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Sugar_tr PF00083.19 KKK26214.1 - 5.2e-28 97.8 10.7 6.6e-28 97.4 7.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KKK26214.1 - 1.7e-10 40.1 20.5 8.9e-10 37.7 13.1 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily AMP-binding PF00501.23 KKK26215.1 - 1e-72 244.8 0.0 1.7e-72 244.1 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.15 KKK26215.1 - 3.4e-26 91.7 0.0 3.2e-24 85.3 0.0 2.5 2 0 0 2 2 2 2 Condensation domain PP-binding PF00550.20 KKK26215.1 - 3.3e-09 36.8 0.0 9.2e-09 35.4 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.1 KKK26215.1 - 2.1e-06 28.5 0.0 7.7e-06 26.7 0.0 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Zeta_toxin PF06414.7 KKK26215.1 - 0.19 10.7 0.0 0.35 9.9 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin ATP-grasp_2 PF08442.5 KKK26216.1 - 5.5e-55 185.8 0.0 7.7e-55 185.4 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.14 KKK26216.1 - 1.5e-10 40.8 0.2 2.5e-10 40.1 0.2 1.3 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.1 KKK26216.1 - 2.4e-10 40.0 0.0 2.1e-09 36.9 0.0 2.1 1 1 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.1 KKK26216.1 - 0.0032 17.2 0.0 0.0056 16.4 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.14 KKK26216.1 - 0.0054 16.3 0.0 0.015 14.9 0.0 1.7 1 1 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp PF02222.17 KKK26216.1 - 0.016 14.6 0.0 0.042 13.1 0.0 1.7 1 1 0 1 1 1 0 ATP-grasp domain CPSase_L_D2 PF02786.12 KKK26216.1 - 0.037 13.3 0.0 0.082 12.1 0.0 1.6 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain TauD PF02668.11 KKK26217.1 - 8.7e-12 45.2 2.1 1.2e-10 41.4 1.5 2.0 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Syndecan PF01034.15 KKK26218.1 - 0.26 10.9 0.3 0.53 9.9 0.2 1.4 1 0 0 1 1 1 0 Syndecan domain Gly-zipper_OmpA PF13436.1 KKK26218.1 - 4.1 7.0 11.0 1.7 8.2 5.1 2.3 1 1 1 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain Piwi PF02171.12 KKK26219.1 - 2.9e-73 246.4 0.0 5.7e-73 245.5 0.0 1.5 1 0 0 1 1 1 1 Piwi domain DUF1785 PF08699.5 KKK26219.1 - 8.2e-14 50.7 0.1 1.8e-13 49.5 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) PAZ PF02170.17 KKK26219.1 - 5.9e-13 48.2 0.0 3.2e-12 45.8 0.0 2.0 1 1 0 1 1 1 1 PAZ domain DUF2371 PF10177.4 KKK26220.1 - 0.086 12.7 0.2 0.18 11.6 0.2 1.6 1 1 0 1 1 1 0 Uncharacterised conserved protein (DUF2371) DUF508 PF04370.7 KKK26220.1 - 4.1 7.0 10.5 0.063 12.9 0.5 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF508) Myco_19_kDa PF05481.7 KKK26220.1 - 4.5 7.0 9.0 0.17 11.7 1.5 2.0 2 0 0 2 2 2 0 Mycobacterium 19 kDa lipoprotein antigen APH PF01636.18 KKK26222.1 - 0.04 13.6 0.6 4.3 6.9 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family MFS_1 PF07690.11 KKK26223.1 - 3.4e-28 98.3 21.5 1.8e-27 95.9 13.3 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily Glyco_transf_90 PF05686.7 KKK26224.1 - 2.3e-17 62.7 3.0 1.6e-13 50.1 1.7 2.9 2 1 0 2 2 2 2 Glycosyl transferase family 90 Ferric_reduct PF01794.14 KKK26224.1 - 5.8e-08 32.8 0.9 5.8e-08 32.8 0.6 2.2 2 0 0 2 2 2 1 Ferric reductase like transmembrane component DUF3357 PF11837.3 KKK26224.1 - 0.16 11.8 0.2 6.9 6.5 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) B3_4 PF03483.12 KKK26225.1 - 1.3e-24 86.5 0.1 2.7e-24 85.5 0.0 1.6 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.10 KKK26225.1 - 7e-18 64.2 0.0 1.8e-14 53.3 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetase B5 domain HEAT PF02985.17 KKK26226.1 - 2.2e-42 139.3 15.5 0.0028 17.5 0.1 13.1 14 0 0 14 14 14 12 HEAT repeat HEAT_2 PF13646.1 KKK26226.1 - 9.6e-36 121.9 0.2 1.2e-08 35.1 0.0 8.0 2 2 5 7 7 7 7 HEAT repeats Vac14_Fab1_bd PF12755.2 KKK26226.1 - 6.2e-12 45.7 1.4 0.002 18.4 0.0 7.3 5 2 3 8 8 8 2 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 KKK26226.1 - 1.9e-11 44.1 3.2 0.13 12.7 0.0 9.2 7 2 3 10 10 10 2 HEAT-like repeat Adaptin_N PF01602.15 KKK26226.1 - 2.1e-06 26.3 6.6 3.9e-05 22.1 0.4 3.9 3 1 1 4 4 4 3 Adaptin N terminal region CLASP_N PF12348.3 KKK26226.1 - 0.0027 17.0 0.8 0.18 11.1 0.1 3.8 3 2 1 4 4 4 1 CLASP N terminal DUF2435 PF10363.4 KKK26226.1 - 0.004 17.0 3.5 3.2 7.6 0.1 4.3 3 1 1 4 4 4 1 Protein of unknown function (DUF2435) Cnd1 PF12717.2 KKK26226.1 - 0.085 12.6 3.0 2.6 7.8 0.1 3.9 2 1 1 3 3 3 0 non-SMC mitotic condensation complex subunit 1 Proteasom_PSMB PF10508.4 KKK26226.1 - 0.13 10.5 2.4 0.72 8.0 0.0 2.6 3 0 0 3 3 3 0 Proteasome non-ATPase 26S subunit Arm PF00514.18 KKK26226.1 - 1.1 9.1 6.7 12 5.8 0.0 5.0 7 0 0 7 7 7 0 Armadillo/beta-catenin-like repeat SLS PF14611.1 KKK26227.1 - 3.5e-53 180.1 0.0 6.3e-53 179.3 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial inner-membrane-bound regulator NT-C2 PF10358.4 KKK26227.1 - 1.7e-34 118.3 0.0 3e-34 117.5 0.0 1.4 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins APG6 PF04111.7 KKK26228.1 - 0.022 13.8 1.9 0.025 13.6 1.3 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 IncA PF04156.9 KKK26228.1 - 0.081 12.5 2.0 0.092 12.3 1.4 1.1 1 0 0 1 1 1 0 IncA protein DinB PF05163.7 KKK26228.1 - 0.089 12.5 0.9 0.11 12.1 0.6 1.1 1 0 0 1 1 1 0 DinB family Nop25 PF09805.4 KKK26228.1 - 0.35 10.9 9.0 0.51 10.4 6.2 1.2 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) AAA_13 PF13166.1 KKK26228.1 - 0.4 9.0 5.0 0.49 8.7 3.5 1.0 1 0 0 1 1 1 0 AAA domain XhlA PF10779.4 KKK26228.1 - 5.6 6.9 7.9 9.3 6.2 5.5 1.5 1 1 0 1 1 1 0 Haemolysin XhlA PAH PF02671.16 KKK26229.1 - 1.2e-06 28.0 1.9 38 3.9 0.0 10.0 11 1 2 13 13 13 0 Paired amphipathic helix repeat NUC130_3NT PF08158.7 KKK26229.1 - 4.2e-06 26.9 17.9 5.1 7.4 0.1 10.6 9 2 4 15 15 15 2 NUC130/3NT domain NAAA-beta PF15508.1 KKK26229.1 - 1e-05 25.8 0.0 8.6 6.7 0.0 6.3 2 2 6 9 9 9 2 beta subunit of N-acylethanolamine-hydrolyzing acid amidase DUF1732 PF08340.6 KKK26229.1 - 0.033 14.0 0.1 2.1 8.2 0.1 3.4 4 0 0 4 4 4 0 Domain of unknown function (DUF1732) DNA_pack_N PF02500.10 KKK26229.1 - 0.18 11.2 0.0 3.1 7.2 0.0 2.8 3 0 0 3 3 3 0 Probable DNA packing protein, N-terminus Myotub-related PF06602.9 KKK26230.1 - 3.5e-125 417.4 0.0 5.9e-125 416.6 0.0 1.4 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Ribosomal_S3_C PF00189.15 KKK26230.1 - 6.4e-16 58.3 0.1 1.3e-15 57.3 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.12 KKK26230.1 - 1.9e-11 43.3 0.1 3.7e-11 42.4 0.0 1.5 1 0 0 1 1 1 1 KH domain Y_phosphatase3 PF13350.1 KKK26230.1 - 0.11 12.6 0.2 0.35 11.0 0.0 1.9 2 0 0 2 2 2 0 Tyrosine phosphatase family Y_phosphatase PF00102.22 KKK26230.1 - 0.16 11.2 0.0 0.36 10.1 0.0 1.5 1 1 0 1 1 1 0 Protein-tyrosine phosphatase Myb_DNA-binding PF00249.26 KKK26231.1 - 1.4e-11 44.2 2.8 1.9e-09 37.4 0.1 2.6 2 1 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KKK26231.1 - 2e-07 30.9 5.1 4.5e-05 23.4 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain FAD_binding_2 PF00890.19 KKK26232.1 - 2.3e-125 418.7 3.4 3.4e-125 418.1 2.4 1.2 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.15 KKK26232.1 - 2e-46 157.0 1.5 2.9e-46 156.4 1.1 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.9 KKK26232.1 - 3e-07 30.5 0.0 0.0031 17.4 0.6 2.9 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KKK26232.1 - 1.7e-05 24.0 0.2 0.012 14.6 0.0 2.3 2 0 0 2 2 2 2 Thi4 family GIDA PF01134.17 KKK26232.1 - 2.2e-05 23.5 1.3 0.036 12.9 1.8 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A DAO PF01266.19 KKK26232.1 - 7.2e-05 21.8 0.2 0.001 18.0 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 KKK26232.1 - 0.0094 15.0 0.2 0.0094 15.0 0.1 1.9 3 0 0 3 3 3 1 FAD binding domain HI0933_like PF03486.9 KKK26232.1 - 0.12 10.8 1.1 0.51 8.7 0.4 2.3 3 0 0 3 3 3 0 HI0933-like protein PARP PF00644.15 KKK26234.1 - 7.7e-65 218.1 0.0 7.7e-65 218.1 0.0 1.7 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.9 KKK26234.1 - 1.7e-42 144.2 0.1 2.7e-42 143.5 0.0 1.3 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.10 KKK26234.1 - 8.9e-22 76.8 0.3 2.2e-21 75.6 0.2 1.7 1 0 0 1 1 1 1 WGR domain BRCT PF00533.21 KKK26234.1 - 7.6e-12 45.2 0.1 2.1e-11 43.8 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 KKK26234.1 - 1.4e-08 34.4 0.2 3e-08 33.4 0.1 1.5 1 0 0 1 1 1 1 twin BRCT domain Ribosomal_60s PF00428.14 KKK26234.1 - 0.011 16.1 3.2 0.026 14.9 2.2 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein p450 PF00067.17 KKK26235.1 - 4e-13 48.7 0.0 5e-13 48.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 zf-C2H2 PF00096.21 KKK26236.1 - 0.00037 20.6 4.1 0.00037 20.6 2.9 3.5 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KKK26236.1 - 0.028 14.7 18.0 0.041 14.2 1.0 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger C1_4 PF07975.7 KKK26236.1 - 0.11 12.4 0.2 0.11 12.4 0.1 2.3 3 0 0 3 3 3 0 TFIIH C1-like domain zf-H2C2_2 PF13465.1 KKK26236.1 - 1.2 9.5 18.7 1.3 9.4 3.6 3.7 3 0 0 3 3 3 0 Zinc-finger double domain Cpn60_TCP1 PF00118.19 KKK26237.1 - 1.4e-139 465.9 10.9 1.7e-139 465.5 7.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Phage_tail_X PF05489.7 KKK26237.1 - 0.041 13.3 0.0 0.11 12.0 0.0 1.6 1 0 0 1 1 1 0 Phage Tail Protein X GTP1_OBG PF01018.17 KKK26237.1 - 0.077 12.6 0.1 0.18 11.4 0.0 1.6 1 0 0 1 1 1 0 GTP1/OBG DUF2277 PF10041.4 KKK26237.1 - 0.09 12.7 0.2 4.3 7.3 0.1 3.0 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2277) AAA PF00004.24 KKK26238.1 - 2.4e-40 137.8 0.0 4.1e-40 137.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KKK26238.1 - 5e-06 26.6 0.0 0.00061 19.9 0.0 2.7 2 1 0 2 2 1 1 AAA domain AAA_5 PF07728.9 KKK26238.1 - 4.4e-05 23.2 0.1 0.00028 20.6 0.0 2.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KKK26238.1 - 0.00025 21.0 0.1 0.0012 18.8 0.0 2.1 2 1 0 2 2 1 1 AAA ATPase domain AAA_2 PF07724.9 KKK26238.1 - 0.00043 20.2 0.0 0.0013 18.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 KKK26238.1 - 0.0016 17.4 0.0 0.0029 16.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_17 PF13207.1 KKK26238.1 - 0.0034 18.2 0.1 0.012 16.4 0.1 2.1 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 KKK26238.1 - 0.0098 14.9 0.0 0.017 14.1 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 KKK26238.1 - 0.0099 15.6 0.1 0.021 14.5 0.1 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_14 PF13173.1 KKK26238.1 - 0.017 15.0 0.0 0.037 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 KKK26238.1 - 0.017 15.0 0.0 0.045 13.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 KKK26238.1 - 0.032 14.0 0.0 0.064 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 KKK26238.1 - 0.051 13.1 0.0 0.61 9.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 KKK26238.1 - 0.052 13.7 0.0 0.13 12.4 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_3 PF07726.6 KKK26238.1 - 0.064 12.8 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 KKK26238.1 - 0.07 12.2 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Sigma54_activ_2 PF14532.1 KKK26238.1 - 0.098 12.7 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain IstB_IS21 PF01695.12 KKK26238.1 - 0.1 11.9 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_18 PF13238.1 KKK26238.1 - 0.1 12.8 0.0 0.37 11.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 KKK26238.1 - 0.14 11.5 0.2 0.48 9.7 0.1 1.8 1 1 0 1 1 1 0 AAA domain BCS1_N PF08740.6 KKK26239.1 - 2.7e-55 186.9 0.3 3.5e-55 186.5 0.2 1.1 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 KKK26239.1 - 1.3e-18 67.4 0.0 2.2e-18 66.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KKK26239.1 - 3.1e-05 24.7 0.0 7.2e-05 23.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 KKK26239.1 - 0.0003 20.2 0.0 0.00058 19.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.8 KKK26239.1 - 0.00052 19.0 0.0 0.00079 18.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_21 PF13304.1 KKK26239.1 - 0.00055 19.9 0.1 0.00088 19.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KKK26239.1 - 0.00058 19.8 0.1 0.0023 17.9 0.0 2.0 2 1 0 2 2 1 1 AAA ATPase domain AAA_18 PF13238.1 KKK26239.1 - 0.00062 20.0 0.0 0.0028 17.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 KKK26239.1 - 0.00079 19.5 0.0 0.0077 16.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 KKK26239.1 - 0.0062 16.4 0.0 0.014 15.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KKK26239.1 - 0.0074 16.0 0.0 0.024 14.3 0.0 2.0 1 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 KKK26239.1 - 0.012 15.7 0.0 0.034 14.3 0.0 1.8 2 0 0 2 2 1 0 RNA helicase ABC_tran PF00005.22 KKK26239.1 - 0.015 15.5 0.0 0.036 14.3 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.1 KKK26239.1 - 0.039 13.4 0.0 0.1 12.1 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain PPV_E1_C PF00519.12 KKK26239.1 - 0.039 12.5 0.0 0.061 11.9 0.0 1.2 1 0 0 1 1 1 0 Papillomavirus helicase DUF258 PF03193.11 KKK26239.1 - 0.043 12.9 0.0 0.22 10.6 0.0 2.1 3 0 0 3 3 3 0 Protein of unknown function, DUF258 KaiC PF06745.8 KKK26239.1 - 0.046 12.8 0.0 0.099 11.7 0.0 1.5 1 0 0 1 1 1 0 KaiC AAA_19 PF13245.1 KKK26239.1 - 0.066 12.9 0.0 0.31 10.8 0.0 2.2 2 0 0 2 2 2 0 Part of AAA domain AAA_24 PF13479.1 KKK26239.1 - 0.084 12.4 0.1 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 KKK26239.1 - 0.099 13.1 0.0 0.19 12.2 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein Linocin_M18 PF04454.7 KKK26239.1 - 0.13 11.1 0.0 0.21 10.4 0.0 1.2 1 0 0 1 1 1 0 Encapsulating protein for peroxidase MMR_HSR1 PF01926.18 KKK26239.1 - 0.15 11.9 0.0 0.46 10.4 0.0 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_11 PF13086.1 KKK26239.1 - 0.16 11.5 0.0 0.25 10.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain Lactamase_B_2 PF12706.2 KKK26240.1 - 7.1e-43 146.4 0.0 9.1e-43 146.0 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 KKK26240.1 - 6.4e-13 48.7 0.0 1.4e-11 44.3 0.0 2.5 2 1 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 KKK26240.1 - 4e-07 29.8 0.1 0.00016 21.4 0.0 2.4 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily DUF2841 PF11001.3 KKK26241.1 - 1.5e-46 157.3 0.1 2.2e-46 156.7 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) TGT PF01702.13 KKK26242.1 - 4.8e-48 163.5 0.0 5.9e-48 163.2 0.0 1.1 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase JmjN PF02375.12 KKK26243.1 - 2.2e-18 65.4 1.1 3.3e-18 64.9 0.7 1.3 1 0 0 1 1 1 1 jmjN domain GIY-YIG PF01541.19 KKK26244.1 - 1.9e-07 31.3 0.0 3.4e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 GIY-YIG catalytic domain FANCL_C PF11793.3 KKK26244.1 - 0.00018 21.4 5.4 0.0003 20.6 3.7 1.3 1 0 0 1 1 1 1 FANCL C-terminal domain Prok-RING_1 PF14446.1 KKK26244.1 - 0.062 13.0 7.1 0.069 12.9 2.6 2.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 TP1 PF02079.11 KKK26244.1 - 5.4 6.8 9.1 12 5.7 0.6 2.5 2 0 0 2 2 2 0 Nuclear transition protein 1 Thymidylate_kin PF02223.12 KKK26245.1 - 1.1e-45 155.3 0.0 1.2e-45 155.1 0.0 1.0 1 0 0 1 1 1 1 Thymidylate kinase KTI12 PF08433.5 KKK26245.1 - 0.0027 16.9 0.0 0.0075 15.5 0.0 1.7 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_28 PF13521.1 KKK26245.1 - 0.0033 17.4 0.0 0.0042 17.0 0.0 1.1 1 0 0 1 1 1 1 AAA domain CPT PF07931.7 KKK26245.1 - 0.011 15.3 0.0 0.022 14.4 0.0 1.4 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_18 PF13238.1 KKK26245.1 - 0.14 12.4 0.0 0.46 10.7 0.0 1.9 1 1 0 1 1 1 0 AAA domain Sugar_tr PF00083.19 KKK26246.1 - 8.4e-27 93.8 10.1 9.1e-27 93.7 7.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KKK26246.1 - 1.4e-08 33.8 8.8 1.7e-08 33.6 6.1 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 KKK26246.1 - 2e-05 23.1 6.4 2e-05 23.1 4.4 1.8 1 1 1 2 2 2 1 MFS/sugar transport protein ABC2_membrane PF01061.19 KKK26246.1 - 0.00016 20.9 8.4 0.0003 20.0 5.8 1.4 1 0 0 1 1 1 1 ABC-2 type transporter Exo5 PF09810.4 KKK26247.1 - 1.3e-133 445.1 0.0 1.6e-133 444.9 0.0 1.1 1 0 0 1 1 1 1 Exonuclease V - a 5' deoxyribonuclease PDDEXK_1 PF12705.2 KKK26247.1 - 0.00013 21.4 0.7 0.00089 18.7 0.5 2.4 1 1 0 1 1 1 1 PD-(D/E)XK nuclease superfamily DUF3445 PF11927.3 KKK26248.1 - 4.1e-56 190.1 0.0 5e-56 189.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Glyco_transf_22 PF03901.12 KKK26249.1 - 8.1e-84 282.0 16.0 9.4e-84 281.8 11.1 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Aldo_ket_red PF00248.16 KKK26250.1 - 3.4e-57 193.4 0.0 4.1e-57 193.1 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family PIG-U PF06728.8 KKK26251.1 - 3.1e-122 408.1 30.6 3.5e-122 407.9 21.2 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U Pescadillo_N PF06732.6 KKK26252.1 - 1.3e-114 382.2 0.1 1.3e-114 382.2 0.0 1.9 2 0 0 2 2 2 1 Pescadillo N-terminus BRCT PF00533.21 KKK26252.1 - 3.2e-07 30.3 0.0 1e-05 25.6 0.0 3.1 2 1 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain Aldedh PF00171.17 KKK26253.1 - 2.3e-164 547.1 0.8 2.6e-164 546.9 0.6 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 KKK26253.1 - 0.00078 18.2 0.0 0.0011 17.7 0.0 1.1 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF1487 PF07368.6 KKK26253.1 - 0.12 11.5 0.0 0.58 9.3 0.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1487) Ribosomal_L36 PF00444.13 KKK26254.1 - 0.0044 16.9 1.8 0.0075 16.2 1.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L36 PALP PF00291.20 KKK26255.1 - 2.1e-70 237.3 1.4 3.1e-70 236.8 0.9 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.13 KKK26255.1 - 1.2e-47 159.3 0.0 2e-24 85.0 0.0 2.4 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase Complex1_LYR PF05347.10 KKK26256.1 - 1.9e-12 46.7 0.2 3e-12 46.1 0.2 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KKK26256.1 - 3.3e-11 43.2 0.3 5.1e-11 42.6 0.2 1.4 1 0 0 1 1 1 1 Complex1_LYR-like GTP_EFTU PF00009.22 KKK26257.1 - 3e-56 189.8 0.3 5.2e-56 189.0 0.2 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 KKK26257.1 - 1.1e-32 111.6 0.0 2.5e-32 110.5 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.13 KKK26257.1 - 8.8e-31 105.9 0.0 2e-30 104.7 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 KKK26257.1 - 1.4e-22 79.3 0.0 3.1e-22 78.2 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 KKK26257.1 - 2.5e-11 43.5 0.1 6.9e-11 42.1 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Acetyltransf_1 PF00583.19 KKK26258.1 - 1.2e-12 47.7 0.3 1.9e-12 47.0 0.2 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KKK26258.1 - 0.0013 18.8 0.6 0.0022 18.0 0.4 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KKK26258.1 - 0.0049 16.5 0.0 0.009 15.7 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 KKK26258.1 - 0.0064 16.5 0.0 0.01 15.9 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain HIG_1_N PF04588.8 KKK26259.1 - 1.6e-26 91.7 0.1 2.2e-26 91.3 0.1 1.2 1 0 0 1 1 1 1 Hypoxia induced protein conserved region Nnf1 PF03980.9 KKK26259.1 - 0.039 13.9 0.7 0.062 13.3 0.5 1.3 1 0 0 1 1 1 0 Nnf1 Abhydrolase_1 PF00561.15 KKK26260.1 - 4.3e-18 65.7 0.1 2e-17 63.5 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KKK26260.1 - 1.8e-11 44.3 0.8 6e-10 39.3 0.5 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 KKK26260.1 - 7.8e-05 22.2 0.0 0.00019 20.9 0.0 1.6 1 0 0 1 1 1 1 Putative esterase CMD PF02627.15 KKK26261.1 - 1.1e-08 34.7 0.3 4.1e-06 26.5 0.1 2.5 2 1 0 2 2 2 2 Carboxymuconolactone decarboxylase family CPSase_L_D3 PF02787.14 KKK26261.1 - 0.011 15.5 0.0 0.016 14.9 0.0 1.2 1 0 0 1 1 1 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain GBP_C PF02841.9 KKK26261.1 - 0.055 12.6 0.2 0.086 12.0 0.1 1.2 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain Mtc PF03820.12 KKK26262.1 - 9.8e-104 346.2 0.1 1.8e-103 345.4 0.0 1.4 1 0 0 1 1 1 1 Tricarboxylate carrier WD40 PF00400.27 KKK26262.1 - 8.3e-28 95.2 14.9 1.1e-06 28.3 0.2 6.9 6 0 0 6 6 6 5 WD domain, G-beta repeat Cu-oxidase_3 PF07732.10 KKK26263.1 - 2.8e-12 46.4 0.0 2.2e-07 30.5 0.0 2.3 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 KKK26263.1 - 2.7e-08 33.3 0.0 0.006 16.0 0.0 2.8 2 1 0 2 2 2 2 Multicopper oxidase Cupredoxin_1 PF13473.1 KKK26263.1 - 0.016 15.0 0.0 3.3 7.6 0.0 2.5 2 0 0 2 2 2 0 Cupredoxin-like domain DUF914 PF06027.7 KKK26264.1 - 2.7e-104 348.6 15.8 3.4e-104 348.3 11.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF914) EamA PF00892.15 KKK26264.1 - 0.0047 16.9 27.5 0.01 15.8 7.3 2.6 2 1 0 2 2 2 2 EamA-like transporter family TPT PF03151.11 KKK26264.1 - 3 7.4 21.0 0.095 12.3 3.7 2.6 3 0 0 3 3 3 0 Triose-phosphate Transporter family DUF814 PF05670.8 KKK26265.1 - 2.3e-06 27.3 0.0 9.8e-06 25.3 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF814) Nodulin-like PF06813.8 KKK26266.1 - 1.5e-17 63.6 1.8 3.7e-17 62.4 1.3 1.7 1 0 0 1 1 1 1 Nodulin-like MFS_1 PF07690.11 KKK26266.1 - 1.7e-17 63.1 36.1 2.7e-15 55.9 21.6 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Lactate_perm PF02652.9 KKK26267.1 - 0.68 8.3 8.3 0.64 8.4 0.2 2.5 3 0 0 3 3 3 0 L-lactate permease Frag1 PF10277.4 KKK26267.1 - 0.94 8.9 8.0 0.78 9.1 0.1 2.3 2 0 0 2 2 2 0 Frag1/DRAM/Sfk1 family Serinc PF03348.10 KKK26268.1 - 7.6e-177 588.3 8.5 8.7e-177 588.1 5.9 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) PGA2 PF07543.7 KKK26268.1 - 0.99 9.2 3.1 20 4.9 0.2 2.4 2 0 0 2 2 2 0 Protein trafficking PGA2 Chitin_synth_2 PF03142.10 KKK26269.1 - 5.7e-229 760.8 0.0 9e-229 760.2 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.16 KKK26269.1 - 3.7e-68 230.2 0.0 2.4e-67 227.5 0.0 2.2 1 1 0 1 1 1 1 Myosin head (motor domain) Cyt-b5 PF00173.23 KKK26269.1 - 7.5e-18 64.1 0.0 1.6e-08 34.2 0.0 2.6 1 1 1 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_trans_2_3 PF13632.1 KKK26269.1 - 2.9e-17 63.0 1.4 2.9e-17 63.0 1.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase family group 2 DEK_C PF08766.6 KKK26269.1 - 1.6e-15 56.6 1.6 1.4e-14 53.5 0.9 2.3 2 0 0 2 2 2 1 DEK C terminal domain Glyco_tranf_2_3 PF13641.1 KKK26269.1 - 5.9e-15 55.6 0.0 2.9e-12 46.8 0.0 2.4 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 KKK26269.1 - 3.4e-06 26.4 0.0 9e-06 25.0 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 KKK26269.1 - 0.0073 15.9 0.0 0.11 12.2 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferase family 2 MutL_C PF08676.6 KKK26270.1 - 2.7e-22 78.9 0.1 6.4e-22 77.7 0.0 1.6 1 0 0 1 1 1 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.14 KKK26270.1 - 7.4e-19 67.3 0.0 6.8e-18 64.2 0.0 2.5 3 0 0 3 3 3 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 KKK26270.1 - 3.1e-12 46.3 0.0 7.8e-12 45.0 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 KKK26270.1 - 4.2e-11 42.5 0.2 1.3e-10 40.9 0.0 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Zn_clus PF00172.13 KKK26270.1 - 1.3e-06 28.1 7.5 2.5e-06 27.2 5.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GCN5L1 PF06320.8 KKK26271.1 - 4.7e-11 42.5 2.3 6.7e-11 42.0 1.6 1.2 1 0 0 1 1 1 1 GCN5-like protein 1 (GCN5L1) Pil1 PF13805.1 KKK26271.1 - 0.00023 20.4 2.5 0.00028 20.1 1.7 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 Raftlin PF15250.1 KKK26271.1 - 0.075 11.5 1.2 0.092 11.2 0.6 1.3 1 1 0 1 1 1 0 Raftlin Cylicin_N PF15241.1 KKK26271.1 - 0.12 12.2 6.2 0.18 11.6 4.3 1.2 1 0 0 1 1 1 0 Cylicin N-terminus HWE_HK PF07536.9 KKK26271.1 - 1.4 9.3 5.6 3.2 8.2 1.1 2.3 1 1 1 2 2 2 0 HWE histidine kinase CAF-1_p150 PF11600.3 KKK26271.1 - 4.8 6.4 11.1 12 5.2 7.7 1.6 1 1 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal FAM53 PF15242.1 KKK26271.1 - 5.7 6.3 12.1 7.4 6.0 8.4 1.1 1 0 0 1 1 1 0 Family of FAM53 ArsA_ATPase PF02374.10 KKK26272.1 - 6.9e-115 383.2 0.0 8e-115 383.0 0.0 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase CbiA PF01656.18 KKK26272.1 - 9.5e-17 61.0 0.2 1.6e-16 60.3 0.2 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 KKK26272.1 - 4.4e-08 33.2 0.0 6.5e-07 29.4 0.0 2.5 2 1 0 2 2 2 1 AAA domain Fer4_NifH PF00142.13 KKK26272.1 - 3.4e-06 26.4 0.1 9.1e-06 25.0 0.0 1.7 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.17 KKK26272.1 - 4.8e-05 22.8 0.3 0.0014 18.1 0.0 2.5 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain AAA_25 PF13481.1 KKK26272.1 - 0.0071 15.7 0.1 0.024 14.0 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KKK26272.1 - 0.008 15.9 0.0 0.026 14.2 0.0 1.8 2 0 0 2 2 2 1 Part of AAA domain MipZ PF09140.6 KKK26272.1 - 0.016 14.3 0.1 0.055 12.5 0.0 1.9 2 0 0 2 2 2 0 ATPase MipZ IstB_IS21 PF01695.12 KKK26272.1 - 0.02 14.3 0.0 0.038 13.4 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AIP3 PF03915.8 KKK26272.1 - 0.023 13.6 0.1 0.033 13.0 0.1 1.2 1 0 0 1 1 1 0 Actin interacting protein 3 PhoH PF02562.11 KKK26272.1 - 0.024 13.8 0.1 0.064 12.4 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein YhjQ PF06564.7 KKK26272.1 - 0.038 13.3 0.0 0.096 12.0 0.0 1.6 2 0 0 2 2 2 0 YhjQ protein NB-ARC PF00931.17 KKK26272.1 - 0.042 12.7 0.0 0.083 11.7 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain Zeta_toxin PF06414.7 KKK26272.1 - 0.16 11.0 0.0 0.32 10.0 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin A1_Propeptide PF07966.7 KKK26272.1 - 0.27 11.1 1.7 0.43 10.4 0.1 2.3 2 0 0 2 2 2 0 A1 Propeptide eIF3_N PF09440.5 KKK26274.1 - 1.9e-52 176.9 0.9 3.9e-52 175.9 0.6 1.6 1 0 0 1 1 1 1 eIF3 subunit 6 N terminal domain PCI PF01399.22 KKK26274.1 - 5.2e-14 52.4 0.1 1.7e-13 50.7 0.0 1.9 2 0 0 2 2 2 1 PCI domain Cucumo_2B PF03263.8 KKK26274.1 - 0.0054 16.9 0.4 0.087 13.1 0.0 2.8 2 1 1 3 3 3 1 Cucumovirus protein 2B PCI_Csn8 PF10075.4 KKK26274.1 - 0.018 14.7 0.0 0.055 13.2 0.0 1.8 1 0 0 1 1 1 0 COP9 signalosome, subunit CSN8 RPN7 PF10602.4 KKK26274.1 - 0.04 13.2 0.0 0.088 12.1 0.0 1.5 1 0 0 1 1 1 0 26S proteasome subunit RPN7 Img2 PF05046.9 KKK26275.1 - 1.5e-29 102.0 0.0 3e-29 101.0 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) ARID PF01388.16 KKK26276.1 - 4.5e-21 74.4 0.5 1.6e-20 72.7 0.0 2.2 2 0 0 2 2 2 1 ARID/BRIGHT DNA binding domain AAA PF00004.24 KKK26277.1 - 1.8e-46 157.6 0.6 5.6e-46 156.0 0.0 2.1 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KKK26277.1 - 3.5e-09 36.5 0.5 1.2e-08 34.8 0.1 2.1 2 2 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 KKK26277.1 - 8e-09 35.6 0.0 1.7e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 KKK26277.1 - 1.6e-07 31.5 0.0 5.4e-07 29.7 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KKK26277.1 - 7.1e-07 29.4 0.7 0.0001 22.4 0.5 2.8 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KKK26277.1 - 1.4e-05 24.9 0.0 6.7e-05 22.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.8 KKK26277.1 - 5.9e-05 22.1 0.0 0.00012 21.0 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_17 PF13207.1 KKK26277.1 - 0.00026 21.7 0.0 0.0014 19.4 0.0 2.1 3 0 0 3 3 1 1 AAA domain RuvB_N PF05496.7 KKK26277.1 - 0.00042 19.4 0.0 0.00098 18.2 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus NACHT PF05729.7 KKK26277.1 - 0.00062 19.4 0.9 0.056 13.0 0.0 3.1 3 1 0 3 3 3 1 NACHT domain Zeta_toxin PF06414.7 KKK26277.1 - 0.00063 18.8 0.1 0.002 17.2 0.0 1.8 2 0 0 2 2 2 1 Zeta toxin NTPase_1 PF03266.10 KKK26277.1 - 0.0007 19.3 0.0 0.0021 17.8 0.0 1.8 1 0 0 1 1 1 1 NTPase UPF0079 PF02367.12 KKK26277.1 - 0.0009 18.8 0.1 0.038 13.6 0.0 2.3 1 1 1 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 RNA_helicase PF00910.17 KKK26277.1 - 0.0012 19.0 0.0 0.0025 17.9 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_19 PF13245.1 KKK26277.1 - 0.0012 18.4 0.1 0.0033 17.1 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_33 PF13671.1 KKK26277.1 - 0.0013 18.6 0.0 0.0027 17.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 KKK26277.1 - 0.0023 17.8 0.0 0.0051 16.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KKK26277.1 - 0.0031 17.1 0.4 0.012 15.2 0.0 2.0 2 1 1 3 3 3 1 AAA domain AAA_3 PF07726.6 KKK26277.1 - 0.0033 17.0 0.0 0.0093 15.5 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 KKK26277.1 - 0.0042 16.5 0.6 0.049 13.0 0.0 2.3 1 1 1 2 2 2 1 AAA domain Sigma54_activat PF00158.21 KKK26277.1 - 0.0051 16.3 0.0 0.23 10.9 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_23 PF13476.1 KKK26277.1 - 0.0054 17.0 0.2 0.54 10.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.8 KKK26277.1 - 0.0055 15.4 0.0 0.0097 14.6 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus Mg_chelatase PF01078.16 KKK26277.1 - 0.0065 15.6 0.0 0.015 14.4 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 KKK26277.1 - 0.0067 16.0 0.0 0.013 15.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 KKK26277.1 - 0.0091 15.7 0.8 0.15 11.6 0.0 2.7 2 1 1 3 3 3 1 Archaeal ATPase IstB_IS21 PF01695.12 KKK26277.1 - 0.013 14.9 0.3 0.033 13.6 0.0 1.8 2 0 0 2 2 1 0 IstB-like ATP binding protein AAA_30 PF13604.1 KKK26277.1 - 0.02 14.4 0.1 0.083 12.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain Bac_DnaA PF00308.13 KKK26277.1 - 0.027 14.0 0.0 0.05 13.2 0.0 1.4 1 0 0 1 1 1 0 Bacterial dnaA protein AAA_18 PF13238.1 KKK26277.1 - 0.03 14.6 0.0 0.097 12.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.1 KKK26277.1 - 0.064 13.3 0.0 0.36 10.8 0.0 2.3 1 1 0 1 1 1 0 Sigma-54 interaction domain KaiC PF06745.8 KKK26277.1 - 0.099 11.7 0.8 0.47 9.5 0.0 2.3 3 0 0 3 3 3 0 KaiC ABC_tran PF00005.22 KKK26277.1 - 0.12 12.6 0.1 0.46 10.7 0.0 2.1 2 0 0 2 2 2 0 ABC transporter Viral_Hsp90 PF03225.9 KKK26277.1 - 0.13 10.5 0.0 0.2 9.8 0.0 1.2 1 0 0 1 1 1 0 Viral heat shock protein Hsp90 homologue Parvo_NS1 PF01057.12 KKK26277.1 - 0.17 10.7 0.0 0.31 9.8 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Asp PF00026.18 KKK26278.1 - 4.1e-109 364.6 0.0 5.3e-109 364.3 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KKK26278.1 - 6.1e-12 45.7 0.1 1.8e-11 44.2 0.1 1.8 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 KKK26278.1 - 1.7e-06 28.4 0.2 0.047 14.1 0.0 3.1 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.1 KKK26278.1 - 5.2e-06 26.1 0.0 2.6e-05 23.8 0.0 2.0 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal NIF PF03031.13 KKK26279.1 - 2e-26 92.5 0.0 4.7e-26 91.3 0.0 1.6 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase PTCB-BRCT PF12738.2 KKK26279.1 - 4.8e-09 35.9 0.2 9.3e-09 35.0 0.1 1.5 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 KKK26279.1 - 7e-08 32.5 0.0 2.2e-07 30.9 0.0 1.9 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain Aft1_HRA PF11786.3 KKK26280.1 - 1.4e-28 98.9 11.1 1.4e-28 98.9 7.7 2.9 3 0 0 3 3 3 1 Aft1 HRA domain Aft1_HRR PF11787.3 KKK26280.1 - 2.1e-22 79.9 2.2 2.1e-22 79.9 1.6 3.7 3 1 1 4 4 4 1 Aft1 HRR domain Aft1_OSA PF11785.3 KKK26280.1 - 1.1e-19 70.6 6.4 1.1e-19 70.6 4.4 2.7 2 1 1 3 3 3 1 Aft1 osmotic stress response (OSM) domain bZIP_1 PF00170.16 KKK26280.1 - 1.8e-13 50.2 4.7 3.2e-13 49.4 3.2 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KKK26280.1 - 2.5e-06 27.2 4.7 5.6e-06 26.0 3.2 1.6 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 KKK26280.1 - 0.0085 16.3 2.4 0.0085 16.3 1.6 1.9 1 1 1 2 2 2 1 bZIP Maf transcription factor Macoilin PF09726.4 KKK26280.1 - 0.11 10.7 7.2 0.15 10.3 5.0 1.1 1 0 0 1 1 1 0 Transmembrane protein Transthyretin PF00576.16 KKK26281.1 - 1.2e-22 79.9 0.0 4.3e-21 74.9 0.0 2.1 1 1 0 1 1 1 1 HIUase/Transthyretin family GPI-anchored PF10342.4 KKK26281.1 - 0.042 14.3 0.2 0.071 13.5 0.2 1.4 1 0 0 1 1 1 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family GatB_N PF02934.10 KKK26285.1 - 2e-100 335.4 0.0 2.9e-100 334.8 0.0 1.2 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.13 KKK26285.1 - 1.6e-26 92.7 0.1 3.3e-26 91.7 0.0 1.5 1 0 0 1 1 1 1 GatB domain Vitellogenin_N PF01347.17 KKK26285.1 - 0.0018 16.6 0.0 0.0027 16.0 0.0 1.2 1 0 0 1 1 1 1 Lipoprotein amino terminal region NB-ARC PF00931.17 KKK26286.1 - 9.5e-13 47.6 0.0 1.5e-12 46.9 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.1 KKK26286.1 - 3e-07 30.6 0.0 6.4e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KKK26286.1 - 0.00098 19.0 0.1 0.0027 17.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 KKK26286.1 - 0.0013 17.8 0.0 0.0054 15.8 0.0 2.1 2 0 0 2 2 2 1 Zeta toxin AAA_16 PF13191.1 KKK26286.1 - 0.0027 17.7 0.0 0.0068 16.4 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain KaiC PF06745.8 KKK26286.1 - 0.0036 16.4 0.1 0.011 14.9 0.0 1.7 2 0 0 2 2 2 1 KaiC AAA_17 PF13207.1 KKK26286.1 - 0.0062 17.3 0.0 0.03 15.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 KKK26286.1 - 0.0073 15.9 0.0 0.015 14.9 0.0 1.5 1 0 0 1 1 1 1 NACHT domain RuvB_N PF05496.7 KKK26286.1 - 0.029 13.4 0.0 0.051 12.6 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus RP-C_C PF11800.3 KKK26286.1 - 0.1 12.2 1.0 0.26 10.9 0.1 1.9 2 0 0 2 2 2 0 Replication protein C C-terminal region DUF676 PF05057.9 KKK26287.1 - 2.1e-05 23.9 0.1 5.2e-05 22.6 0.0 1.5 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.2 KKK26287.1 - 0.00012 22.0 0.0 0.00018 21.4 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 KKK26287.1 - 0.0011 18.6 0.0 0.0022 17.5 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 KKK26287.1 - 0.0093 15.7 0.0 0.02 14.6 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family ECH PF00378.15 KKK26288.1 - 1e-46 159.0 0.0 1.3e-46 158.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Arginase PF00491.16 KKK26289.1 - 3.7e-73 246.2 0.1 4.5e-73 245.9 0.1 1.0 1 0 0 1 1 1 1 Arginase family MARVEL PF01284.18 KKK26290.1 - 0.00099 18.9 17.8 0.0015 18.3 12.3 1.3 1 0 0 1 1 1 1 Membrane-associating domain Lyase_1 PF00206.15 KKK26291.1 - 2.4e-88 296.3 0.0 3.2e-88 295.9 0.0 1.2 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.1 KKK26291.1 - 9.5e-26 89.6 0.1 4.5e-25 87.5 0.0 2.1 2 0 0 2 2 2 1 Argininosuccinate lyase C-terminal CRM1_C PF08767.6 KKK26294.1 - 6.8e-12 44.9 0.1 7.3e-12 44.8 0.0 1.0 1 0 0 1 1 1 1 CRM1 C terminal GTP_EFTU_D3 PF03143.12 KKK26294.1 - 0.00045 20.3 0.1 0.00054 20.0 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain RGCC PF15151.1 KKK26294.1 - 0.085 13.2 0.0 0.093 13.1 0.0 1.1 1 0 0 1 1 1 0 Response gene to complement 32 protein family Med17 PF10156.4 KKK26295.1 - 4.5e-127 424.1 0.0 5.7e-127 423.8 0.0 1.1 1 0 0 1 1 1 1 Subunit 17 of Mediator complex DAO PF01266.19 KKK26296.1 - 1.1e-46 159.4 0.2 1.3e-46 159.1 0.1 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KKK26296.1 - 0.00053 19.9 0.6 0.0014 18.6 0.4 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 KKK26296.1 - 0.0047 17.0 0.0 0.29 11.1 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KKK26296.1 - 0.0074 16.0 0.0 0.13 12.0 0.1 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 KKK26296.1 - 0.0082 15.0 0.7 0.013 14.4 0.5 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 KKK26296.1 - 0.011 16.0 0.0 0.067 13.6 0.1 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KKK26296.1 - 0.033 14.0 0.0 0.066 13.0 0.0 1.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KKK26296.1 - 0.18 10.7 0.1 0.31 9.9 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein Amino_oxidase PF01593.19 KKK26296.1 - 0.3 10.1 4.4 1.5 7.7 0.3 3.1 3 1 0 3 3 3 0 Flavin containing amine oxidoreductase CorA PF01544.13 KKK26297.1 - 6.2e-44 150.1 0.0 7.6e-44 149.8 0.0 1.1 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein MFS_1 PF07690.11 KKK26298.1 - 1.8e-36 125.5 26.2 1.8e-36 125.5 18.2 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF1228 PF06779.9 KKK26298.1 - 0.14 12.1 3.4 0.16 11.9 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1228) adh_short PF00106.20 KKK26299.1 - 9e-20 71.2 0.2 1.7e-19 70.3 0.1 1.5 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KKK26299.1 - 1.1e-06 28.4 0.2 2.7e-06 27.1 0.1 1.7 2 1 0 2 2 2 1 KR domain NAD_binding_10 PF13460.1 KKK26299.1 - 0.0011 19.0 0.0 0.0032 17.5 0.0 1.7 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KKK26299.1 - 0.0023 17.3 0.0 0.0032 16.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 KKK26299.1 - 0.012 15.3 0.3 0.029 14.1 0.2 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Glyco_hydro_76 PF03663.9 KKK26301.1 - 5e-152 506.5 24.7 7.7e-152 505.9 17.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 ADH_N PF08240.7 KKK26301.1 - 2.4e-26 91.6 0.3 2.2e-25 88.5 0.1 2.4 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KKK26301.1 - 9.3e-22 76.9 3.7 4.2e-21 74.8 1.1 2.3 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KKK26301.1 - 4.6e-06 27.5 0.1 1e-05 26.4 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glyco_hydro_2 PF00703.16 KKK26302.1 - 4.6e-12 46.3 0.1 1.3e-11 44.9 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.13 KKK26302.1 - 5.5e-06 26.0 0.0 1.1e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain DUF3344 PF11824.3 KKK26302.1 - 0.041 13.2 0.4 3.2 7.0 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3344) Glyco_hydro_2_C PF02836.12 KKK26302.1 - 0.15 10.8 0.0 0.24 10.2 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain F-box-like PF12937.2 KKK26303.1 - 0.0012 18.5 1.1 0.013 15.1 0.1 2.6 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KKK26303.1 - 0.0012 18.3 0.2 0.0041 16.7 0.1 1.9 1 0 0 1 1 1 1 F-box domain p450 PF00067.17 KKK26304.1 - 4.4e-76 256.2 0.0 6.4e-76 255.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.13 KKK26304.1 - 4.7e-07 28.9 0.4 8.5e-07 28.1 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain PAP2_3 PF14378.1 KKK26306.1 - 1.1e-18 67.4 15.6 2.5e-15 56.5 1.0 2.6 3 0 0 3 3 3 2 PAP2 superfamily PAP2 PF01569.16 KKK26306.1 - 0.38 10.4 8.0 1 9.0 5.5 1.8 1 1 0 1 1 1 0 PAP2 superfamily DUF4491 PF14898.1 KKK26306.1 - 2.2 8.4 6.4 0.62 10.2 2.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4491) Sugar_tr PF00083.19 KKK26307.1 - 1.7e-26 92.8 29.1 3.2e-17 62.2 4.8 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 KKK26307.1 - 2e-19 69.5 59.5 3.8e-17 62.0 25.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Zn_clus PF00172.13 KKK26308.1 - 1.8e-08 34.1 14.0 3.2e-08 33.3 9.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Methyltransf_11 PF08241.7 KKK26309.1 - 1.4e-15 57.5 0.0 3.5e-15 56.2 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 KKK26309.1 - 9.1e-13 48.5 0.0 1.5e-12 47.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KKK26309.1 - 2.8e-11 43.6 0.0 5.9e-11 42.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KKK26309.1 - 7.5e-11 42.0 0.0 1.1e-10 41.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KKK26309.1 - 2e-10 40.4 0.0 3.1e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KKK26309.1 - 3.8e-10 40.3 0.0 6.5e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KKK26309.1 - 1.4e-07 31.5 0.0 3.6e-07 30.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 KKK26309.1 - 0.0049 15.9 0.0 0.0074 15.4 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.9 KKK26309.1 - 0.09 12.1 0.0 0.39 10.0 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase small domain GFA PF04828.9 KKK26310.1 - 8.9e-21 73.6 5.1 1.2e-20 73.2 3.5 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme NAD_binding_1 PF00175.16 KKK26311.1 - 1.4e-13 51.3 0.0 3e-13 50.3 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 KKK26311.1 - 5.2e-10 39.3 0.0 9.7e-10 38.4 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Globin PF00042.17 KKK26311.1 - 6.6e-10 39.3 0.2 2.4e-09 37.5 0.1 2.0 2 0 0 2 2 2 1 Globin NAD_binding_6 PF08030.7 KKK26311.1 - 1.2e-07 31.7 0.0 1.6e-06 28.0 0.0 2.2 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Protoglobin PF11563.3 KKK26311.1 - 3.5e-06 26.7 0.1 6.7e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Protoglobin CIA30 PF08547.7 KKK26312.1 - 1.9e-37 128.5 0.0 2.1e-37 128.3 0.0 1.0 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) Sugar_tr PF00083.19 KKK26313.1 - 2.7e-20 72.3 28.2 2.4e-18 65.9 19.6 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KKK26313.1 - 2e-06 26.7 38.1 3.6e-05 22.6 7.7 3.2 2 2 1 3 3 3 2 Major Facilitator Superfamily DUF2333 PF10095.4 KKK26313.1 - 0.0014 17.3 0.0 0.0026 16.4 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2333) MFS_1 PF07690.11 KKK26314.1 - 3e-31 108.4 18.1 3e-31 108.4 12.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily YfhO PF09586.5 KKK26314.1 - 0.53 8.2 4.1 0.072 11.1 0.1 1.5 2 0 0 2 2 2 0 Bacterial membrane protein YfhO Amino_oxidase PF01593.19 KKK26315.1 - 4.8e-44 151.1 0.1 1.2e-26 93.8 0.0 2.6 2 1 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KKK26315.1 - 9.8e-16 57.5 0.2 1.9e-15 56.6 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KKK26315.1 - 6.4e-07 29.6 0.5 1.7e-06 28.3 0.2 1.8 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KKK26315.1 - 1.6e-06 27.3 0.0 2.5e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 KKK26315.1 - 2.5e-06 26.2 0.4 3.6e-06 25.7 0.3 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_3 PF01494.14 KKK26315.1 - 5.4e-06 25.6 0.8 1e-05 24.8 0.6 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.19 KKK26315.1 - 1.1e-05 24.4 1.7 1.9e-05 23.7 1.1 1.3 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.16 KKK26315.1 - 3.5e-05 23.4 0.1 6.3e-05 22.5 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.1 KKK26315.1 - 6.4e-05 23.1 0.1 0.00013 22.1 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KKK26315.1 - 0.00014 21.0 0.1 0.00038 19.6 0.0 1.7 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.9 KKK26315.1 - 0.00019 21.3 0.1 0.00029 20.7 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KKK26315.1 - 0.00027 20.1 0.5 0.00045 19.4 0.4 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 KKK26315.1 - 0.00041 19.3 0.5 0.00061 18.7 0.4 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A 3HCDH_N PF02737.13 KKK26315.1 - 0.019 14.6 0.2 0.033 13.8 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lycopene_cycl PF05834.7 KKK26315.1 - 0.031 13.2 0.3 0.044 12.7 0.2 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Shikimate_DH PF01488.15 KKK26315.1 - 0.037 14.1 0.5 0.083 12.9 0.0 1.8 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Trp_halogenase PF04820.9 KKK26315.1 - 0.047 12.3 0.4 0.078 11.5 0.3 1.3 1 0 0 1 1 1 0 Tryptophan halogenase NAD_binding_7 PF13241.1 KKK26315.1 - 0.13 12.5 1.2 0.17 12.1 0.3 1.8 2 1 0 2 2 1 0 Putative NAD(P)-binding YjeF_N PF03853.10 KKK26315.1 - 0.17 11.4 0.0 0.27 10.8 0.0 1.3 1 0 0 1 1 1 0 YjeF-related protein N-terminus ApbA PF02558.11 KKK26315.1 - 0.23 10.9 0.6 0.42 10.0 0.4 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA FA_hydroxylase PF04116.8 KKK26316.1 - 1.5e-14 54.3 10.1 1.5e-14 54.3 7.0 2.3 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily MscL PF01741.13 KKK26317.1 - 4.3e-10 39.8 0.1 4.8e-10 39.6 0.1 1.2 1 0 0 1 1 1 1 Large-conductance mechanosensitive channel, MscL Cutinase PF01083.17 KKK26319.1 - 1.7e-42 145.2 0.3 2.3e-42 144.7 0.2 1.2 1 0 0 1 1 1 1 Cutinase Abhydrolase_1 PF00561.15 KKK26319.1 - 5.9e-05 22.7 0.0 0.00011 21.8 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 KKK26319.1 - 0.00061 19.3 0.0 0.0011 18.4 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 KKK26319.1 - 0.0062 16.3 0.1 0.011 15.5 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KKK26319.1 - 0.015 15.2 0.1 0.022 14.6 0.1 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family PE-PPE PF08237.6 KKK26319.1 - 0.021 14.2 0.0 0.034 13.5 0.0 1.3 1 0 0 1 1 1 0 PE-PPE domain Lipase_3 PF01764.20 KKK26319.1 - 0.065 12.8 0.0 0.097 12.2 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DUF3430 PF11912.3 KKK26320.1 - 0.043 13.6 0.0 0.052 13.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3430) Sugar_tr PF00083.19 KKK26321.1 - 3.8e-133 444.3 22.4 4.4e-133 444.1 15.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KKK26321.1 - 1.2e-21 76.8 37.1 1e-11 44.1 8.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF962 PF06127.6 KKK26321.1 - 0.082 12.8 1.0 0.2 11.6 0.0 2.3 3 1 0 3 3 3 0 Protein of unknown function (DUF962) Glyco_hydro_3 PF00933.16 KKK26322.1 - 3.2e-93 311.9 0.0 4.6e-93 311.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KKK26322.1 - 4.7e-59 199.6 0.0 7.5e-59 198.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KKK26322.1 - 1.1e-25 89.3 0.3 2.6e-25 88.1 0.0 1.9 2 0 0 2 2 2 1 Fibronectin type III-like domain Amidase PF01425.16 KKK26323.1 - 1.2e-84 284.7 0.0 2.5e-84 283.6 0.0 1.5 1 1 0 1 1 1 1 Amidase AAA_10 PF12846.2 KKK26324.1 - 1.7e-05 24.4 0.0 2.2e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain Zot PF05707.7 KKK26324.1 - 0.12 11.7 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) Aldedh PF00171.17 KKK26325.1 - 3.3e-07 29.0 0.0 4e-07 28.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family SAC3_GANP PF03399.11 KKK26326.1 - 1.2e-67 227.4 0.1 1.6e-67 227.0 0.1 1.1 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 KKK26326.1 - 0.0001 22.1 0.0 0.00022 21.0 0.0 1.6 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 Chitin_synth_1 PF01644.12 KKK26327.1 - 1.6e-86 288.1 0.2 2.7e-86 287.4 0.1 1.4 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 KKK26327.1 - 7.3e-34 115.3 0.2 1.6e-33 114.2 0.1 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 KKK26327.1 - 1.2e-20 73.4 0.4 5.5e-19 67.9 0.0 2.4 1 1 0 2 2 2 1 Chitin synthase Glyco_trans_2_3 PF13632.1 KKK26327.1 - 2.5e-08 33.8 0.2 7.3e-08 32.3 0.1 1.9 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 KKK26327.1 - 2e-06 27.7 0.0 4.2e-06 26.7 0.0 1.6 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Metallophos PF00149.23 KKK26329.1 - 8.3e-37 126.5 0.1 4.4e-32 111.0 0.0 2.2 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase Sugar_tr PF00083.19 KKK26330.1 - 1.2e-57 195.4 14.9 1.4e-57 195.2 10.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KKK26330.1 - 2.2e-16 59.5 29.0 1.9e-12 46.5 7.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TSA PF03249.8 KKK26330.1 - 0.039 12.5 4.3 0.079 11.4 3.0 1.4 1 0 0 1 1 1 0 Type specific antigen C_GCAxxG_C_C PF09719.5 KKK26330.1 - 0.094 12.5 0.1 5 6.9 0.0 2.7 2 0 0 2 2 2 0 Putative redox-active protein (C_GCAxxG_C_C) Aldedh PF00171.17 KKK26331.1 - 1e-189 630.6 0.4 1.2e-189 630.5 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Mre11_DNA_bind PF04152.9 KKK26332.1 - 4.5e-60 202.4 0.7 4.5e-60 202.4 0.5 2.2 2 0 0 2 2 2 1 Mre11 DNA-binding presumed domain Metallophos PF00149.23 KKK26332.1 - 6.4e-26 90.9 2.5 9.2e-26 90.4 1.7 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Zein PF01559.11 KKK26332.1 - 0.13 11.5 0.1 0.19 10.9 0.1 1.2 1 0 0 1 1 1 0 Zein seed storage protein BAP PF06639.6 KKK26332.1 - 8.2 6.2 5.8 8.3 6.1 0.0 3.2 3 0 0 3 3 3 0 Basal layer antifungal peptide (BAP) Smg4_UPF3 PF03467.10 KKK26333.1 - 1.8e-27 96.4 0.2 4.9e-27 95.0 0.0 1.9 2 0 0 2 2 2 1 Smg-4/UPF3 family RRM_1 PF00076.17 KKK26333.1 - 4.7e-09 35.7 0.3 3.4e-07 29.7 0.0 3.1 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KKK26333.1 - 1.9e-06 27.7 0.0 1.2e-05 25.1 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KKK26333.1 - 1.3e-05 24.9 0.0 2.9e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KKK26333.1 - 0.0081 15.9 0.1 0.019 14.7 0.0 1.6 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif NUDIX PF00293.23 KKK26334.1 - 6.2e-14 51.7 0.9 1.8e-13 50.3 0.6 1.6 1 1 0 1 1 1 1 NUDIX domain Wyosine_form PF08608.7 KKK26335.1 - 6.6e-24 83.8 0.0 1.7e-23 82.4 0.0 1.8 1 0 0 1 1 1 1 Wyosine base formation Radical_SAM PF04055.16 KKK26335.1 - 9.4e-23 81.2 0.1 2.3e-22 79.9 0.1 1.7 1 0 0 1 1 1 1 Radical SAM superfamily Flavodoxin_1 PF00258.20 KKK26335.1 - 3e-09 37.0 0.8 3.8e-07 30.2 0.5 2.6 1 1 0 1 1 1 1 Flavodoxin Flavodoxin_5 PF12724.2 KKK26335.1 - 0.13 12.2 0.0 0.31 11.0 0.0 1.6 1 0 0 1 1 1 0 Flavodoxin domain Glyco_hydro_72 PF03198.9 KKK26336.1 - 2.8e-125 417.4 0.3 3.6e-125 417.1 0.2 1.1 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.13 KKK26336.1 - 4.7e-05 22.7 0.2 0.0082 15.3 0.0 2.3 2 0 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_C PF02836.12 KKK26336.1 - 0.0073 15.2 0.0 0.017 14.0 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain RAP1 PF07218.6 KKK26336.1 - 1.9 6.5 10.0 3.5 5.6 4.7 2.1 2 0 0 2 2 2 0 Rhoptry-associated protein 1 (RAP-1) F-box-like PF12937.2 KKK26337.1 - 4.4e-10 39.1 0.2 9.4e-10 38.0 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KKK26337.1 - 1.4e-09 37.3 0.8 3.6e-09 36.0 0.2 1.9 2 0 0 2 2 2 1 F-box domain DUF2014 PF09427.5 KKK26337.1 - 0.2 10.7 0.0 0.33 10.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2014) Hira PF07569.6 KKK26337.1 - 0.28 10.3 0.2 22 4.1 0.0 2.9 3 0 0 3 3 3 0 TUP1-like enhancer of split AMP-binding PF00501.23 KKK26338.1 - 1.3e-76 257.6 0.0 1.6e-76 257.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KKK26338.1 - 2.6e-12 47.5 1.1 5.9e-12 46.3 0.8 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ABC_tran PF00005.22 KKK26339.1 - 1.5e-24 86.8 0.0 1.2e-12 48.3 0.0 3.1 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 KKK26339.1 - 7.3e-12 45.8 4.0 0.00031 20.7 0.0 3.3 2 1 0 3 3 3 3 AAA domain SbcCD_C PF13558.1 KKK26339.1 - 5.4e-06 26.2 0.0 0.067 13.1 0.0 2.6 2 0 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.1 KKK26339.1 - 0.0062 16.0 0.0 0.014 14.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.1 KKK26339.1 - 0.012 15.5 0.3 0.23 11.3 0.0 2.6 2 0 0 2 2 2 0 AAA ATPase domain AAA_15 PF13175.1 KKK26339.1 - 0.017 14.1 0.0 0.55 9.2 0.0 2.5 3 0 0 3 3 3 0 AAA ATPase domain AAA_23 PF13476.1 KKK26339.1 - 0.027 14.7 0.4 0.06 13.6 0.3 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 KKK26339.1 - 0.053 13.4 0.1 0.12 12.2 0.0 1.7 2 0 0 2 2 1 0 AAA domain NACHT PF05729.7 KKK26339.1 - 0.13 11.9 0.0 0.3 10.7 0.0 1.6 1 0 0 1 1 1 0 NACHT domain FtsK_SpoIIIE PF01580.13 KKK26339.1 - 0.15 11.5 0.0 0.66 9.4 0.0 2.0 2 0 0 2 2 2 0 FtsK/SpoIIIE family cobW PF02492.14 KKK26339.1 - 0.17 11.3 0.0 0.42 10.0 0.0 1.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF3584 PF12128.3 KKK26339.1 - 0.17 9.1 0.2 0.24 8.6 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) AAA_22 PF13401.1 KKK26339.1 - 0.19 11.8 0.1 1.2 9.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain Tmemb_cc2 PF10267.4 KKK26339.1 - 0.19 10.2 1.4 0.31 9.5 1.0 1.2 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein SR-25 PF10500.4 KKK26339.1 - 1.8 8.0 18.1 3.8 6.9 12.5 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Vps51 PF08700.6 KKK26340.1 - 1.9e-17 62.8 3.4 1.9e-17 62.8 1.3 1.8 2 0 0 2 2 2 1 Vps51/Vps67 COG2 PF06148.6 KKK26340.1 - 0.065 13.1 0.5 0.26 11.1 0.1 2.1 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 MAS20 PF02064.10 KKK26341.1 - 1.4e-16 60.5 0.7 1e-11 44.8 0.4 2.6 2 1 0 2 2 2 2 MAS20 protein import receptor Abhydrolase_3 PF07859.8 KKK26342.1 - 9.9e-40 136.3 0.0 1.2e-39 136.0 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KKK26342.1 - 7.2e-06 25.8 0.0 1.2e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KKK26342.1 - 1.4e-05 24.4 0.0 0.0044 16.2 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family COesterase PF00135.23 KKK26342.1 - 0.0031 16.3 0.1 0.031 12.9 0.1 2.0 1 1 0 1 1 1 1 Carboxylesterase family DLH PF01738.13 KKK26342.1 - 0.0034 16.6 0.0 0.095 11.9 0.0 2.1 2 0 0 2 2 2 1 Dienelactone hydrolase family Peptidase_S15 PF02129.13 KKK26342.1 - 0.0093 15.4 0.0 0.48 9.7 0.0 2.3 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) AXE1 PF05448.7 KKK26342.1 - 0.04 12.4 0.1 3.8 5.9 0.0 2.5 3 0 0 3 3 3 0 Acetyl xylan esterase (AXE1) Fungal_trans PF04082.13 KKK26343.1 - 3.5e-12 45.7 0.3 5.8e-12 45.0 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK26343.1 - 2.8e-06 27.1 8.8 4.9e-06 26.3 6.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain LSM PF01423.17 KKK26344.1 - 4.5e-16 58.1 0.1 6.9e-16 57.5 0.1 1.3 1 0 0 1 1 1 1 LSM domain WH2 PF02205.15 KKK26345.1 - 4.7e-10 38.7 0.9 1.4e-09 37.2 0.6 1.8 1 0 0 1 1 1 1 WH2 motif IU_nuc_hydro PF01156.14 KKK26347.1 - 2.1e-54 184.9 0.0 1.6e-53 181.9 0.0 2.0 1 1 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase D5_N PF08706.6 KKK26348.1 - 0.14 12.2 2.5 0.18 11.9 0.0 2.1 2 0 0 2 2 2 0 D5 N terminal like SURF4 PF02077.10 KKK26349.1 - 3.3e-94 315.2 8.5 3.7e-94 315.0 5.9 1.0 1 0 0 1 1 1 1 SURF4 family Ribosomal_L1 PF00687.16 KKK26351.1 - 2.1e-53 180.9 0.5 2.6e-53 180.6 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family SNF PF00209.13 KKK26351.1 - 0.022 13.2 0.1 0.03 12.8 0.0 1.1 1 0 0 1 1 1 0 Sodium:neurotransmitter symporter family Pyr_redox_3 PF13738.1 KKK26352.1 - 2.5e-15 57.0 0.0 5.6e-15 55.9 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KKK26352.1 - 8.1e-13 47.4 0.0 2.7e-12 45.7 0.0 1.8 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 KKK26352.1 - 1.5e-07 31.4 0.0 9.3e-07 28.9 0.0 2.0 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KKK26352.1 - 2.1e-07 30.8 0.3 0.00016 21.5 0.0 3.1 3 0 0 3 3 3 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 KKK26352.1 - 1.1e-06 28.5 0.1 3.1e-05 23.8 0.0 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 KKK26352.1 - 7.5e-06 25.0 0.0 0.002 17.0 0.0 3.1 3 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.22 KKK26352.1 - 0.00052 20.3 0.0 0.61 10.5 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KKK26352.1 - 0.057 12.4 0.5 0.42 9.5 0.1 2.1 2 0 0 2 2 2 0 FAD binding domain Thi4 PF01946.12 KKK26352.1 - 0.1 11.6 0.3 0.23 10.4 0.0 1.7 2 0 0 2 2 2 0 Thi4 family SR-25 PF10500.4 KKK26352.1 - 5.9 6.3 17.3 0.16 11.4 7.4 1.6 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Arf PF00025.16 KKK26354.1 - 7.4e-80 266.2 0.1 8.7e-80 266.0 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 KKK26354.1 - 4.3e-15 55.3 0.0 5.3e-15 55.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 KKK26354.1 - 3.7e-13 49.1 0.0 4.1e-13 49.0 0.0 1.0 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 KKK26354.1 - 1.9e-12 46.5 1.6 2.2e-09 36.5 0.2 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 KKK26354.1 - 6.7e-11 41.7 0.0 8.1e-11 41.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 KKK26354.1 - 2e-08 34.7 0.0 2.8e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 KKK26354.1 - 2.8e-06 27.2 0.0 3.8e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KKK26354.1 - 0.0087 15.5 0.1 0.074 12.4 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain 6PF2K PF01591.13 KKK26354.1 - 0.011 14.8 0.4 0.018 14.0 0.3 1.6 1 1 0 1 1 1 0 6-phosphofructo-2-kinase AAA_33 PF13671.1 KKK26354.1 - 0.065 13.1 0.1 0.12 12.2 0.1 1.8 1 1 0 1 1 1 0 AAA domain Fungal_trans PF04082.13 KKK26355.1 - 6.1e-21 74.4 1.7 1e-20 73.6 1.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain CorA PF01544.13 KKK26356.1 - 1.4e-06 27.5 2.6 0.0029 16.6 0.6 2.4 2 1 0 2 2 2 2 CorA-like Mg2+ transporter protein VIT1 PF01988.14 KKK26356.1 - 0.036 13.5 1.8 0.058 12.8 1.3 1.3 1 0 0 1 1 1 0 VIT family Septin PF00735.13 KKK26357.1 - 6.6e-103 343.5 0.1 1.1e-102 342.8 0.0 1.4 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 KKK26357.1 - 0.00033 20.6 0.0 0.00069 19.5 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 KKK26357.1 - 0.0021 17.9 3.7 0.72 9.6 0.0 2.8 2 1 1 3 3 3 2 Dynamin family DUF258 PF03193.11 KKK26357.1 - 0.0022 17.2 0.1 0.0056 15.8 0.1 1.6 1 1 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 KKK26357.1 - 0.0025 17.2 0.0 0.068 12.5 0.0 2.2 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_24 PF13479.1 KKK26357.1 - 0.0046 16.5 0.0 0.0086 15.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KKK26357.1 - 0.072 13.9 4.1 0.48 11.2 0.1 2.9 2 2 0 2 2 2 0 AAA domain AIG1 PF04548.11 KKK26357.1 - 0.089 11.8 0.1 0.23 10.5 0.1 1.7 1 1 0 1 1 1 0 AIG1 family Miro PF08477.8 KKK26357.1 - 0.11 12.9 0.0 0.32 11.5 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein DUF3653 PF12375.3 KKK26357.1 - 0.21 11.8 2.2 3.7 7.8 0.7 2.6 2 1 0 2 2 2 0 Phage protein zf-C2H2_4 PF13894.1 KKK26358.1 - 5.1e-07 29.5 15.3 3e-05 24.0 2.1 3.1 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KKK26358.1 - 1.4e-06 28.2 10.8 0.0012 19.0 1.2 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-CGNR PF11706.3 KKK26358.1 - 0.89 9.1 4.6 0.42 10.1 0.7 2.1 2 0 0 2 2 2 0 CGNR zinc finger CHORD PF04968.7 KKK26358.1 - 1.3 9.3 4.8 11 6.3 0.5 2.3 1 1 1 2 2 2 0 CHORD zf-H2C2_2 PF13465.1 KKK26358.1 - 3.3 8.1 15.7 1.1 9.6 2.4 3.3 3 0 0 3 3 3 0 Zinc-finger double domain G_glu_transpept PF01019.16 KKK26359.1 - 2e-146 488.4 0.0 2.3e-146 488.2 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Glyco_tranf_2_3 PF13641.1 KKK26361.1 - 4.1e-27 95.4 0.2 5.8e-27 94.9 0.2 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 KKK26361.1 - 7.8e-09 35.0 0.0 5.2e-08 32.3 0.0 2.1 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 KKK26361.1 - 3.8e-08 33.2 0.0 6.4e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Oxysterol_BP PF01237.13 KKK26362.1 - 5e-130 433.1 0.0 1.7e-129 431.3 0.0 1.9 2 0 0 2 2 2 1 Oxysterol-binding protein ATP12 PF07542.6 KKK26362.1 - 4.5e-38 129.9 1.2 1e-37 128.7 0.8 1.7 1 0 0 1 1 1 1 ATP12 chaperone protein Ank_2 PF12796.2 KKK26362.1 - 9.4e-17 61.1 0.0 3.4e-11 43.3 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KKK26362.1 - 2.9e-15 55.9 0.2 1.8e-10 40.6 0.1 3.8 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 KKK26362.1 - 4.1e-14 51.5 0.0 0.00015 21.4 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.1 KKK26362.1 - 6.3e-12 45.6 0.0 5.3e-06 26.8 0.0 3.9 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KKK26362.1 - 3.4e-11 42.2 0.0 0.0031 17.5 0.0 4.2 3 0 0 3 3 3 3 Ankyrin repeat PH PF00169.24 KKK26362.1 - 5.1e-11 42.7 0.2 1.3e-10 41.4 0.2 1.8 1 0 0 1 1 1 1 PH domain PH_8 PF15409.1 KKK26362.1 - 5.9e-07 29.4 0.9 1.6e-06 28.0 0.6 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain ArgK PF03308.11 KKK26362.1 - 1.5 7.5 5.4 2.6 6.7 0.5 2.9 3 0 0 3 3 3 0 ArgK protein zf-Mss51 PF13824.1 KKK26363.1 - 7.2e-29 99.4 6.1 1.6e-28 98.3 4.3 1.6 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 zf-MYND PF01753.13 KKK26363.1 - 0.012 15.4 2.4 0.015 15.1 0.2 2.0 2 0 0 2 2 2 0 MYND finger zf-HIT PF04438.11 KKK26363.1 - 0.27 10.8 2.7 1.6 8.4 0.2 2.4 2 0 0 2 2 2 0 HIT zinc finger E1-E2_ATPase PF00122.15 KKK26364.1 - 2.7e-21 75.6 0.2 9.5e-21 73.8 0.0 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 KKK26364.1 - 1e-16 61.9 0.0 3.8e-15 56.8 0.0 2.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KKK26364.1 - 1.4e-14 54.6 0.1 9.9e-14 51.9 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KKK26364.1 - 1.3e-10 41.1 0.0 4.5e-10 39.3 0.0 2.0 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KKK26364.1 - 0.00052 19.6 0.2 0.0029 17.2 0.1 2.2 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase MIS13 PF08202.6 KKK26365.1 - 1.1e-45 156.0 7.2 3.1e-44 151.2 5.0 2.3 1 1 0 1 1 1 1 Mis12-Mtw1 protein family TSNR_N PF04705.7 KKK26365.1 - 0.013 15.2 0.0 0.025 14.3 0.0 1.4 1 0 0 1 1 1 0 Thiostrepton-resistance methylase, N terminus L_lactis_ph-MCP PF06673.6 KKK26365.1 - 0.03 13.0 0.2 0.054 12.2 0.1 1.3 1 0 0 1 1 1 0 Lactococcus lactis bacteriophage major capsid protein TSC22 PF01166.13 KKK26365.1 - 0.12 12.4 4.4 0.058 13.3 1.0 2.0 2 0 0 2 2 2 0 TSC-22/dip/bun family DivIC PF04977.10 KKK26365.1 - 0.16 11.4 3.4 0.39 10.2 2.4 1.6 1 0 0 1 1 1 0 Septum formation initiator DUF4140 PF13600.1 KKK26365.1 - 0.39 11.1 4.7 0.26 11.7 0.7 2.6 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) AT_hook PF02178.14 KKK26365.1 - 0.71 9.7 12.0 5.4 7.0 0.5 3.6 2 0 0 2 2 2 0 AT hook motif PS_Dcarbxylase PF02666.10 KKK26366.1 - 1.2e-51 174.9 0.0 1.7e-51 174.3 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.25 KKK26366.1 - 3.6e-23 81.1 0.1 2.5e-13 49.6 0.1 2.5 2 0 0 2 2 2 2 C2 domain EF-hand_7 PF13499.1 KKK26366.1 - 0.0014 18.7 0.3 0.0042 17.1 0.2 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 KKK26366.1 - 0.0093 15.2 0.1 0.029 13.6 0.0 1.9 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 KKK26366.1 - 0.018 14.8 0.0 0.081 12.8 0.0 2.1 1 0 0 1 1 1 0 EF-hand domain EF-hand_5 PF13202.1 KKK26366.1 - 0.047 13.0 0.0 0.14 11.5 0.0 1.9 1 0 0 1 1 1 0 EF hand Sugar_tr PF00083.19 KKK26367.1 - 2.1e-82 277.0 12.3 2.5e-82 276.8 8.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KKK26367.1 - 2.1e-33 115.4 25.2 2.8e-33 115.1 17.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 KKK26367.1 - 0.0014 16.9 1.5 0.0014 16.9 1.0 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) ERO1 PF04137.10 KKK26368.1 - 4.8e-137 456.7 0.0 6.3e-137 456.3 0.0 1.1 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) Peroxin-13_N PF04088.8 KKK26369.1 - 7.7e-59 198.1 0.1 1.2e-58 197.5 0.0 1.3 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_2 PF07653.12 KKK26369.1 - 1.3e-09 37.4 0.0 2.3e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KKK26369.1 - 1.7e-08 33.7 0.0 2.8e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KKK26369.1 - 6.7e-07 28.7 0.1 1e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain Podoplanin PF05808.6 KKK26370.1 - 0.004 16.7 1.2 0.0061 16.1 0.8 1.3 1 0 0 1 1 1 1 Podoplanin SKG6 PF08693.5 KKK26370.1 - 0.0048 16.1 0.5 0.013 14.7 0.3 1.8 1 0 0 1 1 1 1 Transmembrane alpha-helix domain VSP PF03302.8 KKK26370.1 - 0.0094 14.6 2.1 0.0094 14.6 1.4 1.7 2 0 0 2 2 2 1 Giardia variant-specific surface protein Glycophorin_A PF01102.13 KKK26370.1 - 0.029 14.1 2.9 0.059 13.1 2.0 1.6 1 0 0 1 1 1 0 Glycophorin A Sporozoite_P67 PF05642.6 KKK26370.1 - 8.6 4.0 12.2 13 3.5 8.5 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Clr5 PF14420.1 KKK26371.1 - 1.5e-19 69.5 2.6 2.5e-19 68.9 1.8 1.3 1 0 0 1 1 1 1 Clr5 domain Trypan_PARP PF05887.6 KKK26371.1 - 4 7.2 7.6 0.88 9.3 2.9 1.6 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) bZIP_2 PF07716.10 KKK26372.1 - 2.4e-12 46.4 11.4 2.4e-12 46.4 7.9 2.0 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.16 KKK26372.1 - 1.5e-05 24.8 9.6 3.6e-05 23.6 6.7 1.6 1 0 0 1 1 1 1 bZIP transcription factor DUF2984 PF11203.3 KKK26372.1 - 0.06 13.4 2.6 0.11 12.5 1.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2984) Zn_peptidase PF04228.8 KKK26373.1 - 0.055 12.6 0.0 0.79 8.8 0.0 2.0 2 0 0 2 2 2 0 Putative neutral zinc metallopeptidase Arc_PepC_II PF06847.6 KKK26373.1 - 0.073 13.4 0.0 0.17 12.3 0.0 1.6 1 0 0 1 1 1 0 Archaeal Peptidase A24 C-terminus Type II ESSS PF10183.4 KKK26373.1 - 0.53 10.7 5.9 2 8.8 2.8 2.6 2 1 0 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) DUF974 PF06159.8 KKK26374.1 - 1.1e-78 264.2 0.0 1.3e-78 263.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF974) CENP-N PF05238.8 KKK26375.1 - 5.6e-146 486.6 0.0 6.4e-146 486.4 0.0 1.0 1 0 0 1 1 1 1 Kinetochore protein CHL4 like zf-RING_2 PF13639.1 KKK26376.1 - 1.9e-06 27.5 6.2 1.9e-06 27.5 4.3 1.8 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 KKK26376.1 - 0.013 15.5 3.9 0.013 15.5 2.7 1.9 2 0 0 2 2 2 0 RING-H2 zinc finger zf-Apc11 PF12861.2 KKK26376.1 - 0.015 15.0 3.0 0.015 15.0 2.1 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.1 KKK26376.1 - 0.02 14.6 5.9 0.02 14.6 4.1 1.9 2 0 0 2 2 2 0 zinc-RING finger domain Bact_transglu_N PF08379.5 KKK26376.1 - 0.053 13.8 0.1 15 6.0 0.1 2.6 3 0 0 3 3 3 0 Bacterial transglutaminase-like N-terminal region C1_1 PF00130.17 KKK26376.1 - 0.2 11.3 7.8 0.14 11.8 2.2 2.5 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) FANCL_C PF11793.3 KKK26376.1 - 0.25 11.3 10.4 0.16 11.9 5.1 2.1 2 1 0 2 2 2 0 FANCL C-terminal domain MARVEL PF01284.18 KKK26377.1 - 4.8e-31 107.5 11.9 5.5e-31 107.3 8.2 1.0 1 0 0 1 1 1 1 Membrane-associating domain TPT PF03151.11 KKK26378.1 - 3e-25 88.6 11.2 3e-25 88.6 7.8 2.5 2 1 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 KKK26378.1 - 3.3e-08 32.8 21.4 1.3e-07 30.8 14.9 1.8 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 KKK26378.1 - 0.0018 18.3 30.8 0.0021 18.0 7.8 2.5 2 1 0 2 2 2 2 EamA-like transporter family Gly_transf_sug PF04488.10 KKK26379.1 - 1.6e-12 47.7 0.1 2.4e-12 47.1 0.1 1.3 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TOM_sub5 PF15178.1 KKK26379.1 - 0.077 12.7 0.4 3.8 7.2 0.0 3.1 3 0 0 3 3 3 0 Mitochondrial import receptor subunit TOM5 homolog TcdA_TcdB PF12919.2 KKK26379.1 - 3.3 6.0 4.6 4.3 5.6 0.5 2.4 3 0 0 3 3 3 0 TcdA/TcdB catalytic glycosyltransferase domain MFS_1 PF07690.11 KKK26380.1 - 6.1e-23 81.1 40.6 3e-12 45.9 16.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KKK26380.1 - 8.4e-15 54.2 19.9 4.6e-12 45.2 13.8 2.8 1 1 0 1 1 1 1 Sugar (and other) transporter Fungal_trans PF04082.13 KKK26381.1 - 1.5e-35 122.3 2.7 1.5e-19 69.9 0.1 2.4 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK26381.1 - 6.5e-16 57.9 27.5 2.2e-09 37.0 7.7 2.5 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain tRNA_synt_2f PF02092.12 KKK26381.1 - 0.14 10.7 0.0 0.22 10.0 0.0 1.2 1 0 0 1 1 1 0 Glycyl-tRNA synthetase beta subunit Glyco_hydro_28 PF00295.12 KKK26382.1 - 1.1e-29 103.4 4.1 1.1e-29 103.4 2.8 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 28 Pectate_lyase_3 PF12708.2 KKK26382.1 - 1.4e-08 35.1 9.0 1.4e-08 35.1 6.2 2.7 2 1 1 3 3 3 1 Pectate lyase superfamily protein UDPGP PF01704.13 KKK26383.1 - 9.4e-183 607.4 0.3 1.1e-182 607.2 0.2 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase PilO PF04350.8 KKK26383.1 - 0.012 15.4 0.2 0.057 13.3 0.0 2.1 3 0 0 3 3 3 0 Pilus assembly protein, PilO C2 PF00168.25 KKK26384.1 - 7.4e-57 189.1 0.6 1.1e-17 63.6 0.0 5.5 5 0 0 5 5 5 5 C2 domain DUF2404 PF10296.4 KKK26384.1 - 0.0049 16.9 0.1 0.11 12.5 0.0 3.0 3 0 0 3 3 3 1 Putative integral membrane protein conserved region (DUF2404) FKBP_C PF00254.23 KKK26384.1 - 0.024 14.6 0.2 0.15 12.0 0.0 2.5 3 0 0 3 3 3 0 FKBP-type peptidyl-prolyl cis-trans isomerase B56 PF01603.15 KKK26384.1 - 0.069 11.7 0.0 0.11 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) Helicase_C PF00271.26 KKK26385.1 - 0.02 14.7 0.0 0.34 10.7 0.0 2.0 1 1 1 2 2 2 0 Helicase conserved C-terminal domain DUF92 PF01940.11 KKK26386.1 - 9.7e-58 194.9 11.9 1.3e-57 194.5 8.2 1.1 1 0 0 1 1 1 1 Integral membrane protein DUF92 Amidohydro_5 PF13594.1 KKK26387.1 - 3e-15 55.7 0.2 1e-14 54.0 0.2 1.9 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 KKK26387.1 - 1.4e-13 51.2 0.0 1.9e-13 50.8 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 KKK26387.1 - 0.044 13.8 2.2 0.076 13.0 1.6 1.4 1 1 0 1 1 1 0 Amidohydrolase Methyltransf_33 PF10017.4 KKK26388.1 - 1.2e-27 96.2 0.3 2.2e-27 95.4 0.2 1.4 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent FGE-sulfatase PF03781.11 KKK26388.1 - 4.9e-22 78.5 1.8 4.2e-20 72.2 1.2 2.3 1 1 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.2 KKK26388.1 - 6.1e-09 36.2 0.1 8.9e-08 32.5 0.0 2.4 2 0 0 2 2 2 1 DinB superfamily Methyltransf_25 PF13649.1 KKK26388.1 - 0.00072 19.8 0.0 0.0087 16.4 0.0 2.6 1 1 1 2 2 2 1 Methyltransferase domain Aldo_ket_red PF00248.16 KKK26389.1 - 2.8e-64 216.6 0.0 3.6e-64 216.3 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Plasmodium_Vir PF05795.6 KKK26392.1 - 0.43 9.7 4.6 0.6 9.2 3.2 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Macoilin PF09726.4 KKK26392.1 - 1.1 7.4 10.4 1.2 7.2 7.2 1.1 1 0 0 1 1 1 0 Transmembrane protein RAP1 PF07218.6 KKK26392.1 - 3.2 5.7 14.9 4.2 5.3 10.4 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Complex1_LYR PF05347.10 KKK26393.1 - 9.1e-07 28.5 0.5 1.3e-06 28.0 0.4 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KKK26393.1 - 3.7e-05 23.8 0.5 0.00014 22.0 0.5 1.7 2 0 0 2 2 2 1 Complex1_LYR-like Alba PF01918.16 KKK26393.1 - 0.12 12.0 0.0 14 5.3 0.0 2.2 2 0 0 2 2 2 0 Alba DnaJ PF00226.26 KKK26394.1 - 7e-19 67.3 0.4 7e-19 67.3 0.3 2.4 2 1 0 2 2 2 1 DnaJ domain Meleagrin PF08189.6 KKK26395.1 - 0.0056 16.1 1.3 0.0056 16.1 0.9 2.2 2 0 0 2 2 2 1 Meleagrin/Cygnin family AA_permease_2 PF13520.1 KKK26396.1 - 2.1e-45 155.0 47.0 6.8e-45 153.3 32.6 1.6 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KKK26396.1 - 6.3e-22 77.5 33.7 1.1e-21 76.7 23.4 1.3 1 0 0 1 1 1 1 Amino acid permease adh_short PF00106.20 KKK26397.1 - 5.4e-28 97.9 2.9 7.7e-28 97.4 2.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KKK26397.1 - 1.4e-15 57.7 0.0 1.7e-15 57.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KKK26397.1 - 4.1e-09 36.3 2.0 6e-09 35.8 1.4 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KKK26397.1 - 0.0012 18.3 0.1 0.0024 17.3 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KKK26397.1 - 0.0043 17.0 1.8 0.015 15.3 1.0 2.0 1 1 0 1 1 1 1 NADH(P)-binding 3HCDH_N PF02737.13 KKK26397.1 - 0.0046 16.6 0.3 0.009 15.6 0.2 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.14 KKK26397.1 - 0.038 13.0 0.1 0.11 11.5 0.1 1.8 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Eno-Rase_NADH_b PF12242.3 KKK26397.1 - 0.43 10.4 2.5 1.1 9.0 0.3 2.3 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Aldedh PF00171.17 KKK26398.1 - 1.3e-127 425.9 0.0 1.4e-127 425.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 KKK26398.1 - 7e-05 21.7 0.4 0.00051 18.8 0.3 2.0 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) Sterol_MT_C PF08498.5 KKK26399.1 - 2e-30 104.5 0.1 3.2e-30 103.8 0.1 1.3 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.7 KKK26399.1 - 1.6e-21 76.5 0.0 3.2e-21 75.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KKK26399.1 - 3.8e-18 65.5 0.0 5.7e-18 64.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KKK26399.1 - 9.1e-14 51.4 0.0 1.7e-13 50.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KKK26399.1 - 1.7e-13 50.7 0.0 3.5e-13 49.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 KKK26399.1 - 5.9e-13 48.5 0.0 8.2e-13 48.0 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.13 KKK26399.1 - 3.7e-12 45.8 0.0 6.1e-12 45.1 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 KKK26399.1 - 2.7e-11 44.0 0.0 6.4e-11 42.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KKK26399.1 - 3.3e-10 40.0 0.0 1.2e-09 38.2 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KKK26399.1 - 3.4e-10 40.2 0.0 7.1e-10 39.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 KKK26399.1 - 2e-05 24.2 0.0 3.3e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.9 KKK26399.1 - 6.4e-05 22.3 0.0 0.00012 21.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 KKK26399.1 - 0.00024 20.3 0.0 0.00046 19.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_15 PF09445.5 KKK26399.1 - 0.00028 20.5 0.0 0.00042 19.8 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase RrnaAD PF00398.15 KKK26399.1 - 0.0018 17.3 0.0 0.0027 16.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_29 PF03141.11 KKK26399.1 - 0.0018 16.7 0.0 0.0022 16.4 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase MetW PF07021.7 KKK26399.1 - 0.0041 16.5 0.0 0.0067 15.8 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_24 PF13578.1 KKK26399.1 - 0.0046 17.7 0.1 0.022 15.6 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Sfi1 PF08457.5 KKK26399.1 - 0.0062 15.0 0.4 0.0082 14.5 0.3 1.1 1 0 0 1 1 1 1 Sfi1 spindle body protein UPF0020 PF01170.13 KKK26399.1 - 0.0071 15.9 0.0 0.015 14.9 0.0 1.5 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_2 PF00891.13 KKK26399.1 - 0.032 13.4 0.8 0.052 12.7 0.2 1.8 1 1 0 2 2 2 0 O-methyltransferase TehB PF03848.9 KKK26399.1 - 0.042 13.0 0.0 0.084 12.0 0.0 1.5 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_32 PF13679.1 KKK26399.1 - 0.12 12.0 0.1 0.32 10.6 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain Fungal_trans_2 PF11951.3 KKK26400.1 - 2.3e-36 125.2 1.4 3.9e-36 124.4 0.9 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK26400.1 - 8.3e-07 28.8 11.5 1.5e-06 27.9 8.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_S28 PF05577.7 KKK26401.1 - 1.4e-55 188.6 0.1 3.9e-55 187.1 0.1 1.6 1 1 0 1 1 1 1 Serine carboxypeptidase S28 Gln-synt_C PF00120.19 KKK26402.1 - 2e-59 200.8 0.0 2.6e-59 200.5 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain MFS_1 PF07690.11 KKK26403.1 - 3.7e-34 117.9 33.9 3.7e-34 117.9 23.5 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3301 PF11743.3 KKK26403.1 - 0.089 12.3 0.0 0.19 11.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3301) Med27 PF11571.3 KKK26404.1 - 2.4e-24 85.2 0.1 5.5e-24 84.1 0.1 1.6 1 0 0 1 1 1 1 Mediator complex subunit 27 RRM_1 PF00076.17 KKK26406.1 - 1.3e-09 37.5 0.0 2.1e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KKK26406.1 - 1.3e-08 34.5 0.0 2.4e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KKK26406.1 - 1.9e-07 30.9 0.0 3.1e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KKK26406.1 - 0.001 18.7 0.0 0.0019 17.9 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 KKK26406.1 - 0.014 15.2 0.0 0.032 14.0 0.0 1.6 1 0 0 1 1 1 0 RNA binding motif Phosphoesterase PF04185.9 KKK26407.1 - 1.6e-30 106.5 2.9 3e-30 105.6 2.0 1.4 1 1 0 1 1 1 1 Phosphoesterase family DUF3533 PF12051.3 KKK26408.1 - 9.3e-130 432.7 10.1 9.3e-130 432.7 7.0 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3533) Sugar_tr PF00083.19 KKK26408.1 - 1.5e-42 145.7 20.6 1.5e-42 145.7 14.3 2.1 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.11 KKK26408.1 - 8.4e-17 60.9 31.3 8.4e-17 60.9 21.7 4.4 3 2 1 4 4 4 2 Major Facilitator Superfamily NPCC PF08058.6 KKK26408.1 - 0.39 10.5 1.3 1.7 8.5 0.1 2.5 3 0 0 3 3 3 0 Nuclear pore complex component DUF2708 PF10917.3 KKK26409.1 - 1.3 8.8 0.1 1.3 8.8 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2708) Bac_rhamnosid PF05592.6 KKK26410.1 - 6.6e-181 601.9 0.0 7.9e-181 601.7 0.0 1.1 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase Bac_rhamnosid_N PF08531.5 KKK26410.1 - 6.7e-63 211.2 0.1 1.2e-62 210.4 0.0 1.5 1 0 0 1 1 1 1 Alpha-L-rhamnosidase N-terminal domain DUF3344 PF11824.3 KKK26410.1 - 0.043 13.1 0.1 0.073 12.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3344) GDC-P PF02347.11 KKK26411.1 - 6.7e-176 585.1 0.2 2.3e-162 540.5 0.0 2.7 3 0 0 3 3 3 2 Glycine cleavage system P-protein Amidohydro_1 PF01979.15 KKK26411.1 - 1.7e-32 113.4 0.1 4.7e-32 111.9 0.0 1.8 2 0 0 2 2 2 1 Amidohydrolase family Amidohydro_3 PF07969.6 KKK26411.1 - 0.0013 18.0 0.4 0.094 11.9 0.0 2.5 2 0 0 2 2 2 1 Amidohydrolase family DegT_DnrJ_EryC1 PF01041.12 KKK26411.1 - 0.0031 16.6 1.2 0.046 12.7 0.0 2.3 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Amidohydro_5 PF13594.1 KKK26411.1 - 0.025 14.4 0.0 0.072 12.9 0.0 1.8 1 0 0 1 1 1 0 Amidohydrolase SPOR PF05036.8 KKK26411.1 - 0.043 13.9 0.0 0.15 12.2 0.0 2.0 1 0 0 1 1 1 0 Sporulation related domain CWC25 PF12542.3 KKK26412.1 - 4.2e-22 78.4 0.0 4.2e-22 78.4 0.0 3.9 3 1 0 3 3 3 1 Pre-mRNA splicing factor Cir_N PF10197.4 KKK26412.1 - 3.5e-14 52.5 9.3 3.5e-14 52.5 6.4 4.6 4 1 1 5 5 5 1 N-terminal domain of CBF1 interacting co-repressor CIR Adaptin_N PF01602.15 KKK26413.1 - 1.3e-127 426.2 10.7 1.7e-127 425.9 7.4 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 KKK26413.1 - 1.1e-16 61.1 4.3 2.4e-16 60.0 0.1 3.0 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 KKK26413.1 - 6.3e-16 58.4 3.0 2.9e-09 37.0 0.0 4.7 2 2 3 5 5 5 3 HEAT repeats HEAT PF02985.17 KKK26413.1 - 6e-07 29.0 8.9 0.0069 16.3 0.0 6.1 9 0 0 9 9 9 2 HEAT repeat Atx10homo_assoc PF09759.4 KKK26413.1 - 1.7e-06 27.6 0.1 0.082 12.6 0.0 3.8 3 0 0 3 3 3 2 Spinocerebellar ataxia type 10 protein domain HEAT_EZ PF13513.1 KKK26413.1 - 0.00097 19.5 5.7 0.99 9.9 0.0 6.0 5 1 1 6 6 6 1 HEAT-like repeat Arm PF00514.18 KKK26413.1 - 0.0049 16.6 5.2 0.57 10.0 0.0 4.8 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat CLASP_N PF12348.3 KKK26413.1 - 0.011 15.1 1.7 1.1 8.5 0.0 3.1 4 0 0 4 4 4 0 CLASP N terminal DUF1077 PF06417.7 KKK26414.1 - 9.9e-53 176.7 2.1 1.2e-52 176.4 1.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) Fungal_trans PF04082.13 KKK26415.1 - 4.3e-06 25.7 0.6 7.6e-06 24.9 0.2 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Paf67 PF10255.4 KKK26416.1 - 1.1e-158 528.3 0.0 1.3e-158 528.1 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 DUF1254 PF06863.7 KKK26416.1 - 0.055 13.2 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1254) TPR_2 PF07719.12 KKK26416.1 - 0.063 13.2 0.0 0.44 10.5 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat AAR2 PF05282.6 KKK26417.1 - 5.1e-103 344.7 0.0 6.6e-103 344.4 0.0 1.0 1 0 0 1 1 1 1 AAR2 protein PP2C_C PF07830.8 KKK26417.1 - 0.11 12.6 0.1 0.47 10.6 0.1 2.0 1 0 0 1 1 1 0 Protein serine/threonine phosphatase 2C, C-terminal domain Aminotran_4 PF01063.14 KKK26418.1 - 1.1e-25 90.4 0.0 1.6e-25 89.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class IV Ribosomal_S11 PF00411.14 KKK26419.1 - 4.7e-14 52.4 0.5 5.6e-14 52.2 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S11 Fe-S_biosyn PF01521.15 KKK26420.1 - 4.7e-11 42.6 0.0 1.2e-10 41.2 0.0 1.7 1 1 0 1 1 1 1 Iron-sulphur cluster biosynthesis RHINO PF15319.1 KKK26420.1 - 0.4 10.4 4.7 0.58 9.9 3.2 1.2 1 0 0 1 1 1 0 RAD9, RAD1, HUS1-interacting nuclear orphan protein Aminotran_5 PF00266.14 KKK26421.1 - 3.1e-08 32.7 0.0 1.5e-07 30.5 0.0 1.9 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 KKK26421.1 - 0.0017 17.4 0.0 0.0031 16.5 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Chitin_bind_3 PF03067.10 KKK26422.1 - 8.7e-07 29.3 0.0 1.7e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 Chitin binding domain CTF_NFI PF00859.13 KKK26422.1 - 0.00066 19.5 7.7 0.0015 18.3 5.4 1.7 1 0 0 1 1 1 1 CTF/NF-I family transcription modulation region Glyco_hydro_61 PF03443.9 KKK26422.1 - 0.0073 16.1 0.0 0.016 15.0 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 UPF0029 PF01205.14 KKK26423.1 - 1.5e-28 98.6 0.0 3.1e-28 97.6 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.17 KKK26423.1 - 3.4e-11 43.0 0.0 6e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 RWD domain DnaJ PF00226.26 KKK26424.1 - 6.3e-16 57.8 0.4 1e-15 57.1 0.1 1.5 2 0 0 2 2 2 1 DnaJ domain Asparaginase PF00710.15 KKK26425.1 - 1.7e-103 345.7 0.0 2.4e-103 345.2 0.0 1.1 1 0 0 1 1 1 1 Asparaginase Ank_2 PF12796.2 KKK26425.1 - 2.6e-14 53.2 0.1 5.3e-14 52.3 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 KKK26425.1 - 2e-11 43.0 1.8 2.5e-05 23.8 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 KKK26425.1 - 7.8e-11 41.8 1.7 2.5e-09 37.0 0.2 3.3 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 KKK26425.1 - 1.3e-09 38.2 1.4 6.5e-06 26.5 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KKK26425.1 - 3.6e-07 29.7 0.8 0.032 14.4 0.0 3.8 4 0 0 4 4 4 2 Ankyrin repeat MTTB PF06253.6 KKK26425.1 - 0.034 11.9 0.2 0.05 11.3 0.1 1.1 1 0 0 1 1 1 0 Trimethylamine methyltransferase (MTTB) Fungal_trans PF04082.13 KKK26426.1 - 1.5e-14 53.4 1.5 2.6e-14 52.7 1.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK26426.1 - 2.8e-07 30.3 11.5 6.3e-07 29.2 7.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_L4 PF00573.17 KKK26427.1 - 1.1e-42 145.5 0.7 1.5e-42 145.1 0.5 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.1 KKK26427.1 - 3.1e-31 107.0 1.1 7.9e-31 105.7 0.7 1.7 1 0 0 1 1 1 1 60S ribosomal protein L4 C-terminal domain Tetraspannin PF00335.15 KKK26428.1 - 0.25 10.5 2.7 1.7 7.8 0.2 2.4 2 0 0 2 2 2 0 Tetraspanin family Aminotran_1_2 PF00155.16 KKK26429.1 - 9.7e-10 37.9 0.0 2.3e-09 36.6 0.0 1.7 1 1 0 1 1 1 1 Aminotransferase class I and II LCCL PF03815.14 KKK26430.1 - 1.9e-23 82.2 0.2 3.1e-23 81.5 0.1 1.3 1 0 0 1 1 1 1 LCCL domain Phosphoesterase PF04185.9 KKK26431.1 - 5e-66 223.4 1.3 8.3e-66 222.7 0.9 1.3 1 1 0 1 1 1 1 Phosphoesterase family Phosphodiest PF01663.17 KKK26431.1 - 0.0049 16.2 3.2 0.0075 15.6 2.2 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF1996 PF09362.5 KKK26432.1 - 1.6e-75 253.8 0.0 1.6e-75 253.8 0.0 2.4 2 1 0 2 2 2 1 Domain of unknown function (DUF1996) Rifin_STEVOR PF02009.11 KKK26432.1 - 2.2 7.8 7.2 3 7.4 5.0 1.2 1 0 0 1 1 1 0 Rifin/stevor family Macoilin PF09726.4 KKK26432.1 - 7.4 4.7 8.1 9.7 4.3 5.6 1.2 1 0 0 1 1 1 0 Transmembrane protein 2OG-FeII_Oxy_2 PF13532.1 KKK26433.1 - 3.1e-05 23.8 0.0 3.7e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Nucleoplasmin PF03066.10 KKK26433.1 - 2.1 7.8 5.6 2.9 7.3 3.9 1.2 1 0 0 1 1 1 0 Nucleoplasmin CENP-B_dimeris PF09026.5 KKK26433.1 - 4.4 7.5 9.0 8.2 6.7 6.3 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain TAP42 PF04177.7 KKK26433.1 - 6.1 5.6 7.2 7.8 5.3 5.0 1.1 1 0 0 1 1 1 0 TAP42-like family Steroid_dh PF02544.11 KKK26434.1 - 3.5e-13 49.5 0.5 8.7e-13 48.2 0.2 1.8 1 1 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase TPPK_C PF12555.3 KKK26434.1 - 2.3 8.0 7.1 8.8 6.1 3.8 2.7 2 1 0 2 2 2 0 Thiamine pyrophosphokinase C terminal YbgT_YccB PF08173.6 KKK26434.1 - 7.8 6.4 9.5 18 5.2 6.0 2.1 2 0 0 2 2 2 0 Membrane bound YbgT-like protein Vac_ImportDeg PF09783.4 KKK26435.1 - 1.7e-48 164.4 0.6 9.7e-48 161.9 0.2 2.0 2 0 0 2 2 2 1 Vacuolar import and degradation protein Ank_2 PF12796.2 KKK26436.1 - 3.2e-25 88.2 0.1 5.6e-16 58.6 0.2 2.7 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ribosomal_L7Ae PF01248.21 KKK26436.1 - 3.8e-25 87.2 0.6 8.2e-25 86.1 0.4 1.6 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Ank PF00023.25 KKK26436.1 - 6.9e-21 72.9 0.3 2e-07 30.4 0.0 4.6 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.1 KKK26436.1 - 8.5e-19 67.1 1.3 4.2e-07 29.9 0.0 4.7 3 2 2 5 5 5 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 KKK26436.1 - 3e-15 56.2 0.0 0.0015 18.9 0.0 3.5 2 1 0 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KKK26436.1 - 7.3e-13 47.4 0.0 0.00019 21.3 0.0 4.5 4 0 0 4 4 4 3 Ankyrin repeat IU_nuc_hydro PF01156.14 KKK26437.1 - 1.8e-91 306.6 0.0 2e-91 306.4 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase HTH_Tnp_Tc5 PF03221.11 KKK26438.1 - 5.6e-18 64.5 0.0 1.1e-17 63.6 0.0 1.4 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain CDO_I PF05995.7 KKK26439.1 - 2.5e-36 124.4 0.5 4.3e-35 120.4 0.4 2.0 1 1 0 1 1 1 1 Cysteine dioxygenase type I DUF1637 PF07847.7 KKK26439.1 - 2e-05 24.0 0.0 2.5e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1637) MMR_HSR1 PF01926.18 KKK26440.1 - 1.4e-18 66.8 0.1 3.5e-18 65.6 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase TGS PF02824.16 KKK26440.1 - 1.7e-18 66.2 0.0 4.3e-18 64.9 0.0 1.7 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.13 KKK26440.1 - 4.4e-10 39.0 0.1 2.6e-09 36.5 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 KKK26440.1 - 4.9e-05 22.8 0.6 0.57 9.5 0.0 4.0 2 2 1 3 3 3 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 KKK26440.1 - 0.00029 20.6 0.4 0.05 13.4 0.0 2.3 1 1 1 2 2 2 2 Dynamin family ArgK PF03308.11 KKK26440.1 - 0.0057 15.4 0.1 0.012 14.4 0.1 1.5 1 0 0 1 1 1 1 ArgK protein Arf PF00025.16 KKK26440.1 - 0.028 13.6 0.2 1.9 7.6 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family Miro PF08477.8 KKK26440.1 - 0.03 14.8 0.1 0.081 13.4 0.0 1.8 2 0 0 2 2 2 0 Miro-like protein Abhydrolase_6 PF12697.2 KKK26441.1 - 3.8e-26 92.3 0.0 1.7e-25 90.2 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KKK26441.1 - 6.2e-11 42.3 0.0 5e-10 39.3 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KKK26441.1 - 3.4e-10 39.8 0.0 2e-09 37.3 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF2305 PF10230.4 KKK26441.1 - 0.076 12.4 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Hydrolase_4 PF12146.3 KKK26441.1 - 0.098 12.5 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Putative lysophospholipase Abhydrolase_2 PF02230.11 KKK26441.1 - 0.11 11.9 0.0 10 5.4 0.0 2.3 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase MR_MLE_C PF13378.1 KKK26442.1 - 6.1e-33 113.1 0.0 1.1e-32 112.3 0.0 1.4 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.11 KKK26442.1 - 1.5e-14 54.0 0.0 1.1e-13 51.1 0.0 2.2 1 1 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MR_MLE PF01188.16 KKK26442.1 - 5.9e-09 36.3 0.0 1.5e-08 35.0 0.0 1.7 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain PXA PF02194.10 KKK26443.1 - 3e-45 154.0 1.1 2.2e-44 151.2 0.1 2.5 3 0 0 3 3 3 1 PXA domain Glyco_transf_8 PF01501.15 KKK26444.1 - 1.9e-33 115.8 0.0 3.3e-33 115.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 8 Nucleotid_trans PF03407.11 KKK26444.1 - 0.082 12.6 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Nucleotide-diphospho-sugar transferase Mannosyl_trans3 PF11051.3 KKK26444.1 - 0.19 11.0 0.0 0.33 10.2 0.0 1.4 1 0 0 1 1 1 0 Mannosyltransferase putative LacAB_rpiB PF02502.13 KKK26445.1 - 1.1e-39 135.2 0.0 2e-39 134.4 0.0 1.4 1 0 0 1 1 1 1 Ribose/Galactose Isomerase U-box PF04564.10 KKK26445.1 - 8.3e-21 73.7 0.0 2.1e-20 72.4 0.0 1.7 1 0 0 1 1 1 1 U-box domain TPR_11 PF13414.1 KKK26445.1 - 2.4e-15 55.9 3.4 3.6e-13 48.9 0.0 3.4 2 1 1 3 3 3 2 TPR repeat TPR_2 PF07719.12 KKK26445.1 - 4.2e-07 29.3 6.5 0.00048 19.8 0.1 5.0 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 KKK26445.1 - 6.3e-05 23.5 10.1 0.0024 18.5 0.0 4.0 3 1 1 4 4 4 2 Tetratricopeptide repeat Apc3 PF12895.2 KKK26445.1 - 0.00014 21.9 0.0 0.00038 20.5 0.0 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.23 KKK26445.1 - 0.00015 21.2 0.2 0.00015 21.2 0.1 4.7 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.1 KKK26445.1 - 0.00026 21.2 4.9 0.27 11.5 0.1 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.1 KKK26445.1 - 0.00043 20.2 2.5 1.2 9.5 0.1 3.9 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 KKK26445.1 - 0.0014 18.5 4.5 0.087 12.7 0.1 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 KKK26445.1 - 0.0027 18.1 6.5 1.6 9.5 0.0 4.5 4 1 0 4 4 4 1 Tetratricopeptide repeat Gly_rich_SFCGS PF14272.1 KKK26445.1 - 0.033 14.0 0.0 0.061 13.2 0.0 1.4 1 0 0 1 1 1 0 Glycine-rich SFCGS GvpG PF05120.7 KKK26445.1 - 0.04 13.7 0.3 0.11 12.3 0.2 1.7 1 0 0 1 1 1 0 Gas vesicle protein G ACBP PF00887.14 KKK26446.1 - 3e-20 71.6 0.7 4.3e-20 71.1 0.5 1.2 1 0 0 1 1 1 1 Acyl CoA binding protein Methyltransf_31 PF13847.1 KKK26447.1 - 2.2e-06 27.3 0.0 2.9e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KKK26447.1 - 1.7e-05 25.0 0.0 2.3e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KKK26447.1 - 4.5e-05 22.6 0.0 5.6e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.7 KKK26447.1 - 0.0017 18.8 0.0 0.0024 18.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KKK26447.1 - 0.0039 17.6 0.0 0.0056 17.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KKK26447.1 - 0.0054 16.7 0.0 0.0086 16.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 KKK26447.1 - 0.017 14.8 0.0 0.018 14.7 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 KKK26447.1 - 0.045 13.1 0.0 0.057 12.7 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_18 PF12847.2 KKK26447.1 - 0.056 14.0 0.0 0.078 13.5 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain RseA_C PF03873.8 KKK26448.1 - 0.037 13.9 0.0 0.07 13.0 0.0 1.4 1 0 0 1 1 1 0 Anti sigma-E protein RseA, C-terminal domain NOT2_3_5 PF04153.13 KKK26449.1 - 2.1e-34 118.2 0.5 8.3e-34 116.3 0.0 2.1 2 0 0 2 2 2 1 NOT2 / NOT3 / NOT5 family MRP-L47 PF06984.8 KKK26450.1 - 1.1e-19 70.1 0.2 1.5e-19 69.6 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Clc-like PF07062.7 KKK26450.1 - 0.37 9.9 2.8 0.63 9.2 1.9 1.3 1 0 0 1 1 1 0 Clc-like Tyr-DNA_phospho PF06087.7 KKK26451.1 - 7.2e-151 502.7 0.0 9.1e-151 502.4 0.0 1.1 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase DIE2_ALG10 PF04922.7 KKK26451.1 - 3.1e-76 256.8 14.5 8.8e-70 235.6 5.6 2.4 2 1 0 2 2 2 2 DIE2/ALG10 family PLDc_2 PF13091.1 KKK26451.1 - 0.018 14.7 0.0 1.8 8.3 0.0 2.3 2 0 0 2 2 2 0 PLD-like domain Sld5 PF05916.6 KKK26452.1 - 1.8e-31 108.5 0.0 2.6e-31 108.0 0.0 1.2 1 0 0 1 1 1 1 GINS complex protein CUE PF02845.11 KKK26453.1 - 2.1e-12 46.2 0.0 3.2e-12 45.6 0.0 1.3 1 0 0 1 1 1 1 CUE domain SMC_N PF02463.14 KKK26454.1 - 5e-67 225.3 11.5 1.8e-66 223.5 8.0 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 KKK26454.1 - 1.4e-23 83.1 1.4 2.7e-22 78.9 0.2 2.9 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 KKK26454.1 - 6.9e-14 52.4 7.1 9.2e-06 25.8 0.0 3.7 3 0 0 3 3 3 2 AAA domain AAA_23 PF13476.1 KKK26454.1 - 7e-13 49.3 9.8 7e-13 49.3 6.8 6.4 2 2 2 4 4 4 1 AAA domain AAA_29 PF13555.1 KKK26454.1 - 8.2e-05 22.0 0.0 0.0002 20.8 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain TMF_DNA_bd PF12329.3 KKK26454.1 - 0.00064 19.4 9.4 0.00064 19.4 6.5 11.5 9 2 3 12 12 12 2 TATA element modulatory factor 1 DNA binding AAA_13 PF13166.1 KKK26454.1 - 0.0014 17.1 28.4 0.0014 17.1 19.7 6.5 3 2 2 5 5 5 2 AAA domain Reo_sigmaC PF04582.7 KKK26454.1 - 0.0015 17.8 28.9 0.53 9.4 1.2 5.9 3 2 2 5 5 5 3 Reovirus sigma C capsid protein GAS PF13851.1 KKK26454.1 - 0.006 15.8 12.8 0.006 15.8 8.9 7.0 2 2 4 6 6 6 2 Growth-arrest specific micro-tubule binding DUF1796 PF08795.5 KKK26454.1 - 0.15 11.7 12.6 7.9 6.0 0.2 3.8 2 1 1 3 3 3 0 Putative papain-like cysteine peptidase (DUF1796) zf-RING_2 PF13639.1 KKK26455.1 - 6.6e-14 51.4 5.5 1e-13 50.8 3.8 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 KKK26455.1 - 1.2e-08 34.9 1.7 2.1e-08 34.1 1.2 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 KKK26455.1 - 4.9e-08 32.5 4.4 7.5e-08 31.9 3.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KKK26455.1 - 3.9e-07 29.9 4.3 6.3e-07 29.3 3.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KKK26455.1 - 9.6e-06 25.2 2.9 1.5e-05 24.6 2.0 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KKK26455.1 - 0.00015 21.3 2.3 0.00024 20.6 1.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.2 KKK26455.1 - 0.00033 20.6 5.9 0.0005 20.0 4.1 1.3 1 0 0 1 1 1 1 RING-variant domain zf-Apc11 PF12861.2 KKK26455.1 - 0.00044 20.0 2.1 0.00098 18.9 1.5 1.6 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Nse PF11789.3 KKK26455.1 - 0.018 14.5 2.1 0.04 13.4 1.0 1.8 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.1 KKK26455.1 - 0.19 11.3 3.6 0.3 10.7 2.5 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.1 KKK26455.1 - 0.22 11.2 2.5 0.47 10.2 1.7 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING-like PF08746.6 KKK26455.1 - 0.23 11.4 2.6 0.41 10.6 1.8 1.3 1 0 0 1 1 1 0 RING-like domain FANCL_C PF11793.3 KKK26455.1 - 0.26 11.2 3.3 0.49 10.3 2.3 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain Prok-RING_1 PF14446.1 KKK26455.1 - 0.64 9.7 4.8 0.47 10.2 2.2 1.5 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 PHD PF00628.24 KKK26455.1 - 2.3 7.9 3.9 3.7 7.3 2.7 1.3 1 0 0 1 1 1 0 PHD-finger ECM11 PF15463.1 KKK26456.1 - 4.8e-38 130.5 1.7 4.8e-38 130.5 1.2 3.1 3 0 0 3 3 3 1 Extracellular mutant protein 11 RNA_pol_I_TF PF04090.7 KKK26456.1 - 6e-12 45.2 0.0 8.5e-11 41.4 0.0 2.2 1 1 0 1 1 1 1 RNA polymerase I specific initiation factor Rieske PF00355.21 KKK26457.1 - 2.6e-09 36.5 0.0 4.9e-09 35.6 0.0 1.6 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.1 KKK26457.1 - 9e-05 22.1 0.0 0.00018 21.1 0.0 1.4 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Pkinase PF00069.20 KKK26458.1 - 1.2e-13 50.8 0.0 3.9e-13 49.1 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK26458.1 - 0.00081 18.5 0.0 0.41 9.6 0.0 2.9 3 0 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.1 KKK26458.1 - 0.0015 17.5 0.2 0.25 10.2 0.1 2.6 3 0 0 3 3 3 2 Kinase-like APH PF01636.18 KKK26458.1 - 0.0045 16.7 0.1 0.011 15.4 0.0 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family VPS9 PF02204.13 KKK26459.1 - 9.2e-25 86.6 0.0 2e-24 85.5 0.0 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Lipase_3 PF01764.20 KKK26460.1 - 3.6e-06 26.6 0.0 7.6e-06 25.5 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 KKK26460.1 - 0.046 13.4 0.0 0.083 12.6 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Catalase PF00199.14 KKK26461.1 - 1.8e-184 612.8 1.4 2.3e-184 612.5 1.0 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 KKK26461.1 - 2.9e-12 46.2 0.1 1e-11 44.5 0.0 2.0 2 0 0 2 2 2 1 Catalase-related immune-responsive Fungal_trans_2 PF11951.3 KKK26461.1 - 5.8e-06 25.1 0.4 9.8e-06 24.4 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Sugar_tr PF00083.19 KKK26462.1 - 9.6e-84 281.5 22.1 1.2e-83 281.2 15.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KKK26462.1 - 4.3e-15 55.2 35.0 8.5e-10 37.8 12.0 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily LtrA PF06772.6 KKK26463.1 - 1.2e-24 86.9 14.2 1.6e-24 86.4 9.9 1.2 1 0 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) adh_short_C2 PF13561.1 KKK26464.1 - 4.1e-20 72.5 0.0 2.1e-19 70.2 0.0 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KKK26464.1 - 5.9e-16 58.8 0.2 7.2e-14 52.0 0.1 2.1 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KKK26464.1 - 4.3e-05 23.2 0.2 0.0023 17.6 0.1 2.2 1 1 1 2 2 2 1 KR domain Methyltransf_28 PF02636.12 KKK26464.1 - 0.1 11.9 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase ORC4_C PF14629.1 KKK26465.1 - 1.1e-56 191.4 0.0 1.7e-56 190.8 0.0 1.3 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.1 KKK26465.1 - 4.5e-17 62.6 0.1 1.4e-16 60.9 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain DUF815 PF05673.8 KKK26465.1 - 2.7e-06 26.5 0.1 5e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_22 PF13401.1 KKK26465.1 - 8.8e-06 25.8 0.0 2.4e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 KKK26465.1 - 8.9e-05 22.6 0.0 0.00032 20.8 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) KAP_NTPase PF07693.9 KKK26465.1 - 0.00035 19.6 0.0 0.00069 18.7 0.0 1.4 1 0 0 1 1 1 1 KAP family P-loop domain NACHT PF05729.7 KKK26465.1 - 0.00057 19.5 1.7 0.0035 17.0 0.3 2.7 2 1 0 2 2 2 1 NACHT domain Arch_ATPase PF01637.13 KKK26465.1 - 0.0016 18.1 0.0 0.0042 16.8 0.0 1.6 1 1 0 1 1 1 1 Archaeal ATPase AAA_29 PF13555.1 KKK26465.1 - 0.002 17.6 0.1 0.0061 16.0 0.1 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain ThiS-like PF14453.1 KKK26465.1 - 0.008 15.9 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 1 ThiS-like ubiquitin PIF1 PF05970.9 KKK26465.1 - 0.16 10.8 0.1 0.28 10.0 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase Zn_clus PF00172.13 KKK26466.1 - 1.5e-11 44.0 10.9 2.7e-11 43.1 7.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KKK26466.1 - 1.6e-10 40.1 0.2 2.5e-10 39.5 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Rer1 PF03248.8 KKK26467.1 - 2.3e-81 271.5 6.0 2.6e-81 271.4 4.2 1.0 1 0 0 1 1 1 1 Rer1 family ECH PF00378.15 KKK26468.1 - 4.3e-72 242.1 0.2 5.3e-72 241.8 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family ECH_C PF13766.1 KKK26468.1 - 0.018 15.2 0.0 0.033 14.3 0.0 1.5 1 0 0 1 1 1 0 2-enoyl-CoA Hydratase C-terminal region Peptidase_S49 PF01343.13 KKK26468.1 - 0.035 13.8 0.3 0.1 12.3 0.0 1.8 2 0 0 2 2 2 0 Peptidase family S49 TIM PF00121.13 KKK26469.1 - 4.2e-43 147.1 0.0 5.2e-43 146.8 0.0 1.1 1 0 0 1 1 1 1 Triosephosphate isomerase DHO_dh PF01180.16 KKK26470.1 - 5e-63 212.7 0.1 2.4e-53 181.0 0.0 2.1 2 0 0 2 2 2 2 Dihydroorotate dehydrogenase PcrB PF01884.12 KKK26470.1 - 0.00021 20.6 1.3 0.38 9.9 0.1 2.3 2 0 0 2 2 2 2 PcrB family FMN_dh PF01070.13 KKK26470.1 - 0.045 12.6 0.1 0.68 8.7 0.1 2.3 2 0 0 2 2 2 0 FMN-dependent dehydrogenase PLA2_B PF01735.13 KKK26471.1 - 3.5e-194 645.5 1.1 4.2e-194 645.2 0.8 1.1 1 0 0 1 1 1 1 Lysophospholipase catalytic domain Paf1 PF03985.8 KKK26473.1 - 6.6e-40 137.1 0.7 1.2e-27 96.7 0.0 3.1 2 1 0 2 2 2 2 Paf1 Actin PF00022.14 KKK26473.1 - 8.1e-29 100.2 0.0 4.1e-17 61.6 0.0 2.4 2 1 0 2 2 2 2 Actin MreB_Mbl PF06723.8 KKK26473.1 - 0.00012 20.8 0.1 0.13 10.8 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein DUF2114 PF09887.4 KKK26473.1 - 0.26 9.5 0.0 0.36 9.1 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2114) Arf PF00025.16 KKK26474.1 - 8.8e-74 246.4 0.0 1.1e-73 246.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 KKK26474.1 - 1.9e-12 46.7 0.0 2.4e-12 46.4 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 KKK26474.1 - 3e-10 39.7 0.0 3.5e-10 39.4 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 KKK26474.1 - 6.4e-10 38.2 0.4 4.5e-06 25.5 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 KKK26474.1 - 4.4e-09 35.8 0.0 5.4e-09 35.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 KKK26474.1 - 4.3e-08 33.6 0.0 5.8e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 KKK26474.1 - 5.5e-06 26.3 0.0 7.7e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KKK26474.1 - 3.9e-05 23.1 0.0 0.0057 16.1 0.0 2.1 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 KKK26474.1 - 0.023 13.9 0.4 0.087 12.1 0.3 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B ADH_zinc_N PF00107.21 KKK26475.1 - 2.5e-27 94.9 0.2 3.4e-27 94.5 0.2 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KKK26475.1 - 1.2e-08 34.6 0.3 2.4e-08 33.6 0.2 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 KKK26475.1 - 1.4e-06 29.2 0.0 2.2e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF3419 PF11899.3 KKK26476.1 - 8.4e-155 515.1 0.1 1.2e-154 514.7 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_23 PF13489.1 KKK26476.1 - 9.4e-13 48.1 0.0 7.5e-11 42.0 0.0 3.0 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_12 PF08242.7 KKK26476.1 - 7.4e-09 35.9 0.0 2.4e-08 34.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KKK26476.1 - 2.5e-08 34.4 0.0 1.2e-07 32.2 0.0 2.2 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KKK26476.1 - 9.1e-08 31.8 0.0 2.3e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KKK26476.1 - 1.6e-06 28.1 0.0 1.7e-05 24.8 0.0 2.5 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.7 KKK26476.1 - 5.9e-06 26.6 0.0 0.00052 20.4 0.0 3.1 2 1 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 KKK26476.1 - 8.1e-06 25.1 0.0 3.4e-05 23.0 0.0 1.9 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 KKK26476.1 - 3.8e-05 23.9 0.0 0.00022 21.5 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.14 KKK26476.1 - 0.00016 21.3 0.0 0.0003 20.3 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.1 KKK26476.1 - 0.0043 16.7 0.0 0.0094 15.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_28 PF02636.12 KKK26476.1 - 0.12 11.7 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase DEAD PF00270.24 KKK26477.1 - 1.8e-24 86.1 0.0 3.5e-24 85.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KKK26477.1 - 9.6e-11 41.3 0.0 5e-10 39.1 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF1998 PF09369.5 KKK26477.1 - 1.5e-09 38.2 0.8 2.3e-08 34.4 0.6 2.6 1 1 0 1 1 1 1 Domain of unknown function (DUF1998) Formyl_trans_N PF00551.14 KKK26478.1 - 3.2e-35 121.3 0.0 3.8e-35 121.0 0.0 1.1 1 0 0 1 1 1 1 Formyl transferase Fungal_trans_2 PF11951.3 KKK26479.1 - 9.2e-14 50.8 1.3 1.5e-13 50.1 0.9 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK26479.1 - 1.1e-07 31.6 8.6 1.9e-07 30.8 5.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3987 PF13148.1 KKK26480.1 - 5.6 5.4 8.5 8.8 4.7 5.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Yip1 PF04893.12 KKK26481.1 - 3e-14 52.8 13.3 4.8e-14 52.2 9.2 1.4 1 0 0 1 1 1 1 Yip1 domain DUF1282 PF06930.7 KKK26481.1 - 0.68 9.5 9.2 1.3 8.6 6.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1282) 4HBT PF03061.17 KKK26482.1 - 4.2e-11 42.8 0.1 6.1e-11 42.3 0.1 1.2 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.1 KKK26482.1 - 0.0017 18.1 0.1 0.0029 17.4 0.1 1.4 1 1 0 1 1 1 1 Thioesterase-like superfamily GDI PF00996.13 KKK26483.1 - 1.4e-185 616.8 0.0 1.7e-185 616.5 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor Pyr_redox PF00070.22 KKK26483.1 - 0.06 13.7 0.3 0.89 9.9 0.1 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KKK26483.1 - 0.11 12.4 0.1 0.29 11.2 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Ran_BP1 PF00638.13 KKK26484.1 - 2.4e-19 69.5 0.1 4.4e-19 68.7 0.0 1.3 1 0 0 1 1 1 1 RanBP1 domain PPR_2 PF13041.1 KKK26485.1 - 2.8e-25 88.0 1.0 8.2e-17 60.9 0.3 3.4 3 0 0 3 3 3 2 PPR repeat family PPR_3 PF13812.1 KKK26485.1 - 8.5e-08 31.9 1.2 0.13 12.6 0.0 5.9 6 0 0 6 6 6 2 Pentatricopeptide repeat domain PPR PF01535.15 KKK26485.1 - 1.9e-06 27.4 5.3 0.14 12.1 0.2 4.4 5 0 0 5 5 5 3 PPR repeat PPR_1 PF12854.2 KKK26485.1 - 0.00022 20.6 1.6 0.32 10.5 0.0 3.9 4 0 0 4 4 4 2 PPR repeat YodL PF14191.1 KKK26485.1 - 0.2 12.1 0.1 0.45 11.0 0.0 1.5 1 0 0 1 1 1 0 YodL-like zf-C2H2_4 PF13894.1 KKK26486.1 - 2.9e-06 27.2 12.7 0.00062 19.9 1.3 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KKK26486.1 - 6e-06 26.2 4.0 6e-06 26.2 2.8 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.21 KKK26486.1 - 1.6e-05 24.9 11.7 0.0071 16.6 1.1 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type PNPOx_C PF10590.4 KKK26487.1 - 2e-20 71.9 5.9 9.5e-20 69.8 2.9 2.4 2 0 0 2 2 2 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Pyridox_oxidase PF01243.15 KKK26487.1 - 3.3e-10 39.8 0.0 0.001 19.0 0.0 2.8 3 0 0 3 3 3 2 Pyridoxamine 5'-phosphate oxidase EamA PF00892.15 KKK26488.1 - 0.00019 21.4 9.1 0.00032 20.7 5.2 1.9 1 1 1 2 2 2 1 EamA-like transporter family EmrE PF13536.1 KKK26488.1 - 0.00022 21.3 6.6 0.00022 21.3 4.6 1.6 1 1 1 2 2 2 1 Multidrug resistance efflux transporter UPF0546 PF10639.4 KKK26488.1 - 0.0014 18.4 0.9 0.0017 18.1 0.7 1.2 1 0 0 1 1 1 1 Uncharacterised protein family UPF0546 TPT PF03151.11 KKK26488.1 - 0.86 9.2 6.8 3.6 7.1 4.7 1.8 1 1 0 1 1 1 0 Triose-phosphate Transporter family UCR_TM PF02921.9 KKK26489.1 - 3.5e-20 71.9 1.7 6.1e-20 71.2 1.2 1.4 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region Rieske PF00355.21 KKK26489.1 - 2.7e-17 62.0 0.2 6.9e-17 60.8 0.1 1.7 1 1 1 2 2 2 1 Rieske [2Fe-2S] domain She9_MDM33 PF05546.6 KKK26490.1 - 3e-94 314.4 8.2 4.3e-94 313.9 5.7 1.2 1 0 0 1 1 1 1 She9 / Mdm33 family DUF1183 PF06682.7 KKK26490.1 - 0.0051 16.4 0.4 0.011 15.3 0.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1183) PsbH PF00737.15 KKK26490.1 - 0.02 14.4 1.0 0.02 14.4 0.7 1.8 2 0 0 2 2 2 0 Photosystem II 10 kDa phosphoprotein DRY_EERY PF09750.4 KKK26490.1 - 0.052 13.6 4.8 0.12 12.4 3.4 1.5 1 0 0 1 1 1 0 Alternative splicing regulator DUF2175 PF09943.4 KKK26490.1 - 0.057 13.4 2.1 0.068 13.2 0.5 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) Voltage_CLC PF00654.15 KKK26491.1 - 3.9e-91 305.7 31.0 3.9e-91 305.7 21.5 1.8 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 KKK26491.1 - 1.4e-14 53.5 0.0 7.4e-06 25.6 0.0 2.6 2 0 0 2 2 2 2 CBS domain CBFD_NFYB_HMF PF00808.18 KKK26492.1 - 2.2e-14 53.2 2.2 2.3e-14 53.2 0.1 2.0 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 KKK26492.1 - 0.0016 18.5 0.1 0.0029 17.6 0.1 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 SH3_9 PF14604.1 KKK26493.1 - 2.4e-06 27.0 0.1 5.4e-06 25.8 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KKK26493.1 - 0.0024 17.2 0.0 0.0054 16.0 0.0 1.6 1 0 0 1 1 1 1 SH3 domain EphA2_TM PF14575.1 KKK26493.1 - 0.078 13.3 0.0 0.16 12.4 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.1 KKK26493.1 - 0.089 12.4 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family Cofilin_ADF PF00241.15 KKK26494.1 - 3e-23 82.0 0.0 3.3e-23 81.9 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein DUF1262 PF06880.6 KKK26494.1 - 0.086 13.1 0.0 0.13 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1262) Pmp3 PF01679.12 KKK26495.1 - 3.3e-20 71.5 6.1 4.2e-20 71.1 4.3 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator DUF4106 PF13388.1 KKK26495.1 - 1.5 7.7 7.0 1.5 7.6 4.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) Peptidase_C14 PF00656.17 KKK26496.1 - 0.0013 18.4 0.0 0.0021 17.7 0.0 1.2 1 0 0 1 1 1 1 Caspase domain Raptor_N PF14538.1 KKK26496.1 - 0.014 15.2 0.0 0.024 14.4 0.0 1.5 1 0 0 1 1 1 0 Raptor N-terminal CASPase like domain ABC_membrane PF00664.18 KKK26497.1 - 6.5e-93 311.1 35.4 1.8e-47 162.0 10.4 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KKK26497.1 - 1.5e-52 177.5 1.1 9.6e-33 113.3 0.0 2.8 3 0 0 3 3 2 2 ABC transporter AAA_29 PF13555.1 KKK26497.1 - 1.3e-08 34.2 0.6 0.00055 19.4 0.2 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.14 KKK26497.1 - 1.4e-08 34.2 1.0 9e-06 25.0 0.5 3.5 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KKK26497.1 - 3.9e-07 30.3 0.1 0.9 9.4 0.0 3.4 3 0 0 3 3 3 3 AAA domain DUF258 PF03193.11 KKK26497.1 - 4.1e-07 29.3 0.1 0.043 13.0 0.0 3.2 3 0 0 3 3 3 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 KKK26497.1 - 1.1e-06 29.5 0.3 0.057 14.2 0.0 3.0 2 1 0 2 2 2 2 AAA domain AAA_25 PF13481.1 KKK26497.1 - 2.5e-05 23.7 0.1 0.31 10.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 KKK26497.1 - 2.7e-05 24.2 5.0 0.045 13.7 0.0 3.7 4 1 0 4 4 3 2 AAA ATPase domain AAA_22 PF13401.1 KKK26497.1 - 7.4e-05 22.9 0.6 0.57 10.3 0.0 3.3 2 1 0 2 2 2 2 AAA domain AAA PF00004.24 KKK26497.1 - 9.3e-05 22.6 0.2 2 8.6 0.1 3.7 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ResIII PF04851.10 KKK26497.1 - 0.00015 21.6 0.5 0.91 9.3 0.0 3.5 4 0 0 4 4 4 2 Type III restriction enzyme, res subunit AAA_33 PF13671.1 KKK26497.1 - 0.00033 20.5 0.0 0.66 9.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain ABC_ATPase PF09818.4 KKK26497.1 - 0.001 17.7 0.5 0.0032 16.1 0.0 1.9 2 0 0 2 2 2 1 Predicted ATPase of the ABC class AAA_18 PF13238.1 KKK26497.1 - 0.0011 19.2 0.0 1.9 8.8 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 KKK26497.1 - 0.0014 18.3 0.0 2.4 7.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_10 PF12846.2 KKK26497.1 - 0.0017 17.8 2.6 2.5 7.4 0.1 3.6 4 0 0 4 4 4 2 AAA-like domain AAA_30 PF13604.1 KKK26497.1 - 0.0019 17.8 1.5 2 7.9 0.0 3.6 4 0 0 4 4 4 1 AAA domain AAA_23 PF13476.1 KKK26497.1 - 0.0027 18.0 2.7 0.54 10.5 0.0 3.4 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.1 KKK26497.1 - 0.0032 17.1 0.2 1.5 8.6 0.0 2.9 2 0 0 2 2 2 1 Part of AAA domain SRP54 PF00448.17 KKK26497.1 - 0.0058 16.0 0.3 0.54 9.6 0.0 2.7 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Zeta_toxin PF06414.7 KKK26497.1 - 0.0059 15.7 0.2 1.8 7.5 0.0 2.9 3 0 0 3 3 3 1 Zeta toxin RNA_helicase PF00910.17 KKK26497.1 - 0.0067 16.5 0.1 1.8 8.7 0.0 3.2 3 0 0 3 3 2 1 RNA helicase Rad17 PF03215.10 KKK26497.1 - 0.0078 14.9 0.1 0.17 10.5 0.0 2.1 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein MobB PF03205.9 KKK26497.1 - 0.0089 15.7 0.1 5.6 6.6 0.1 2.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.1 KKK26497.1 - 0.018 14.9 0.0 2.2 8.1 0.0 2.9 3 0 0 3 3 2 0 AAA domain DUF87 PF01935.12 KKK26497.1 - 0.021 14.6 0.1 4.5 7.0 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function DUF87 PRK PF00485.13 KKK26497.1 - 0.051 13.1 0.0 2.6 7.5 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family RXT2_N PF08595.6 KKK26497.1 - 0.051 13.3 0.3 0.12 12.1 0.2 1.6 1 0 0 1 1 1 0 RXT2-like, N-terminal AAA_28 PF13521.1 KKK26497.1 - 0.074 13.0 0.9 4.1 7.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.15 KKK26497.1 - 0.1 12.2 0.1 3.3 7.3 0.0 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase NACHT PF05729.7 KKK26497.1 - 0.21 11.2 0.8 14 5.2 0.0 2.6 2 0 0 2 2 2 0 NACHT domain MMR_HSR1 PF01926.18 KKK26497.1 - 0.22 11.5 1.8 17 5.3 0.0 3.5 4 0 0 4 4 4 0 50S ribosome-binding GTPase CDC45 PF02724.9 KKK26497.1 - 1.3 6.9 7.4 0.052 11.5 0.2 1.9 2 0 0 2 2 2 0 CDC45-like protein PPR_2 PF13041.1 KKK26498.1 - 1.5e-46 156.1 6.6 3.2e-10 39.8 0.0 13.6 11 3 4 15 15 15 10 PPR repeat family PPR_3 PF13812.1 KKK26498.1 - 1.4e-32 109.2 26.2 0.00063 19.8 0.1 16.5 18 0 0 18 18 18 7 Pentatricopeptide repeat domain PPR PF01535.15 KKK26498.1 - 3.6e-24 82.9 17.9 0.00043 20.0 0.0 13.5 16 1 0 16 16 16 6 PPR repeat PPR_1 PF12854.2 KKK26498.1 - 2.3e-21 74.9 0.0 1.3e-06 27.7 0.0 9.6 10 1 0 10 10 10 3 PPR repeat RPM2 PF08579.6 KKK26498.1 - 6.5e-10 39.1 0.0 0.00021 21.3 0.0 5.2 5 0 0 5 5 5 2 Mitochondrial ribonuclease P subunit (RPM2) ECSIT PF06239.6 KKK26498.1 - 0.00055 18.8 0.1 0.086 11.6 0.0 3.3 3 0 0 3 3 3 1 Evolutionarily conserved signalling intermediate in Toll pathway RPN7 PF10602.4 KKK26498.1 - 0.0041 16.5 1.5 15 4.9 0.0 4.0 3 1 1 4 4 4 2 26S proteasome subunit RPN7 GHMP_kinases_N PF00288.21 KKK26499.1 - 3.1e-14 52.7 3.1 4.4e-14 52.3 1.2 2.0 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 KKK26499.1 - 5.2e-10 39.3 0.0 1.1e-09 38.3 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal DUF1206 PF06724.6 KKK26500.1 - 0.0046 16.6 1.1 0.0095 15.6 0.8 1.5 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1206) XPC-binding PF09280.6 KKK26501.1 - 1.9e-23 81.6 12.6 3.8e-23 80.7 8.7 1.5 1 0 0 1 1 1 1 XPC-binding domain UBA PF00627.26 KKK26501.1 - 7.1e-20 70.2 0.7 1.6e-09 37.2 0.1 2.6 2 0 0 2 2 2 2 UBA/TS-N domain ubiquitin PF00240.18 KKK26501.1 - 4.6e-19 67.5 0.7 8e-19 66.8 0.5 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 KKK26501.1 - 5e-08 32.5 0.4 8.3e-08 31.8 0.3 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.1 KKK26501.1 - 0.00035 20.4 0.0 0.0007 19.4 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA_3 PF09288.5 KKK26501.1 - 0.00086 18.8 0.0 0.71 9.5 0.0 2.4 2 0 0 2 2 2 2 Fungal ubiquitin-associated domain Rap1_C PF11626.3 KKK26501.1 - 0.0011 18.8 0.0 0.09 12.6 0.0 2.4 2 0 0 2 2 2 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain CUE PF02845.11 KKK26501.1 - 0.011 15.2 0.0 1.5 8.4 0.0 2.6 2 0 0 2 2 2 0 CUE domain DUF2407 PF10302.4 KKK26501.1 - 0.012 15.7 0.0 0.029 14.5 0.0 1.7 2 0 0 2 2 2 0 DUF2407 ubiquitin-like domain Glyco_transf_22 PF03901.12 KKK26502.1 - 1.7e-61 208.4 24.1 2.3e-61 208.0 16.7 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Skp1 PF01466.14 KKK26503.1 - 1.5e-39 133.8 2.2 1.5e-39 133.8 1.6 1.5 2 0 0 2 2 2 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.10 KKK26503.1 - 1.2e-24 86.1 0.0 3e-24 84.8 0.0 1.7 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain DUF4375 PF14300.1 KKK26503.1 - 0.057 13.4 0.4 0.095 12.6 0.1 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4375) Zn_clus PF00172.13 KKK26504.1 - 4.7e-08 32.8 8.6 9.8e-08 31.7 6.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KKK26504.1 - 2e-06 26.8 0.0 3.4e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain NAD_binding_10 PF13460.1 KKK26505.1 - 1.2e-11 44.9 0.2 8.5e-11 42.1 0.3 2.0 1 1 1 2 2 2 1 NADH(P)-binding NmrA PF05368.8 KKK26505.1 - 1.5e-10 40.7 0.1 5e-07 29.2 0.1 2.9 1 1 1 3 3 3 2 NmrA-like family Epimerase PF01370.16 KKK26505.1 - 0.00016 21.2 0.0 0.00022 20.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 KKK26505.1 - 0.00047 20.1 0.1 0.00085 19.2 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase DapB_N PF01113.15 KKK26505.1 - 0.00067 19.5 0.0 0.0015 18.4 0.0 1.7 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus KR PF08659.5 KKK26505.1 - 0.0064 16.1 0.1 0.012 15.2 0.0 1.5 1 0 0 1 1 1 1 KR domain Semialdhyde_dh PF01118.19 KKK26505.1 - 0.012 15.9 0.0 0.023 14.9 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 KKK26505.1 - 0.024 13.3 0.0 0.035 12.7 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.13 KKK26505.1 - 0.031 14.2 0.0 0.08 12.9 0.0 1.7 2 0 0 2 2 2 0 TrkA-N domain RmlD_sub_bind PF04321.12 KKK26505.1 - 0.048 12.5 0.1 0.071 11.9 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain F420_oxidored PF03807.12 KKK26505.1 - 0.055 13.8 0.6 0.14 12.6 0.4 1.7 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.13 KKK26505.1 - 0.066 12.8 0.1 0.12 12.0 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Ldh_1_N PF00056.18 KKK26505.1 - 0.1 12.4 0.6 0.2 11.4 0.4 1.6 1 1 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain DUF2422 PF10337.4 KKK26506.1 - 2.5e-118 395.7 1.4 2.5e-118 395.7 1.0 4.0 4 1 0 4 4 4 1 Protein of unknown function (DUF2422) MFS_1 PF07690.11 KKK26506.1 - 1.2e-19 70.2 48.9 1.2e-19 70.2 33.9 4.9 3 3 0 3 3 3 1 Major Facilitator Superfamily FUSC_2 PF13515.1 KKK26506.1 - 3.8e-18 65.6 12.0 3.8e-18 65.6 8.3 5.7 5 2 2 7 7 7 1 Fusaric acid resistance protein-like DUF2421 PF10334.4 KKK26506.1 - 4.1e-14 52.7 0.0 1.9e-13 50.5 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2421) DUF939 PF06081.6 KKK26506.1 - 0.00035 20.4 7.1 0.00035 20.4 4.9 4.8 5 1 0 5 5 5 1 Bacterial protein of unknown function (DUF939) DPBB_1 PF03330.13 KKK26507.1 - 2.3e-08 33.8 0.0 3.9e-08 33.1 0.0 1.5 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 KKK26507.1 - 0.067 12.8 0.1 0.1 12.2 0.1 1.3 1 0 0 1 1 1 0 Barwin family Glyco_hydro_92 PF07971.7 KKK26508.1 - 2.5e-58 197.9 2.2 3.4e-58 197.5 1.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Alpha-amylase_C PF02806.13 KKK26509.1 - 2e-25 88.7 0.0 5.1e-25 87.4 0.0 1.7 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.19 KKK26509.1 - 3.9e-19 69.1 0.0 3.3e-14 53.0 0.1 2.5 1 1 1 2 2 2 2 Alpha amylase, catalytic domain CBM_48 PF02922.13 KKK26509.1 - 1.3e-15 57.2 0.1 3.1e-15 55.9 0.0 1.7 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Glyco_hydro_66 PF13199.1 KKK26509.1 - 0.011 14.1 0.2 0.017 13.5 0.1 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 66 Amidase PF01425.16 KKK26510.1 - 3.1e-70 237.2 0.0 1.4e-69 235.1 0.0 1.9 1 1 0 1 1 1 1 Amidase ThiF PF00899.16 KKK26510.1 - 1.2e-39 135.2 0.0 4e-39 133.5 0.0 1.9 2 0 0 2 2 2 1 ThiF family MoeZ_MoeB PF05237.8 KKK26510.1 - 1.3e-28 98.3 0.1 2.7e-28 97.3 0.1 1.6 1 0 0 1 1 1 1 MoeZ/MoeB domain Rhodanese PF00581.15 KKK26510.1 - 1.3e-11 44.8 0.0 2.8e-11 43.7 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain Shikimate_DH PF01488.15 KKK26510.1 - 0.0039 17.2 0.0 0.014 15.5 0.0 1.9 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase DAO PF01266.19 KKK26510.1 - 0.0049 15.8 0.6 0.013 14.3 0.1 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase ApbA PF02558.11 KKK26510.1 - 0.022 14.1 0.0 0.042 13.3 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_7 PF13241.1 KKK26510.1 - 0.064 13.5 0.0 0.29 11.4 0.0 2.0 2 0 0 2 2 2 0 Putative NAD(P)-binding FAD_binding_3 PF01494.14 KKK26510.1 - 0.073 12.1 0.6 0.2 10.6 0.7 1.5 2 0 0 2 2 2 0 FAD binding domain ATP-synt_ab PF00006.20 KKK26511.1 - 1e-61 208.1 0.0 1.6e-61 207.5 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 KKK26511.1 - 9.9e-27 93.6 0.3 2e-26 92.6 0.2 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 KKK26511.1 - 7.2e-24 83.7 1.7 1.9e-23 82.4 0.6 2.1 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain KaiC PF06745.8 KKK26511.1 - 0.0013 17.8 0.2 0.0023 17.0 0.1 1.4 1 0 0 1 1 1 1 KaiC AAA_25 PF13481.1 KKK26511.1 - 0.0033 16.8 0.1 0.043 13.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 KKK26511.1 - 0.0097 15.6 0.0 0.034 13.8 0.0 1.8 2 0 0 2 2 2 1 Archaeal ATPase AAA PF00004.24 KKK26511.1 - 0.013 15.6 0.1 0.51 10.5 0.0 2.7 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KKK26511.1 - 0.014 15.3 0.2 0.37 10.7 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain DUF258 PF03193.11 KKK26511.1 - 0.023 13.8 0.2 0.042 13.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 NACHT PF05729.7 KKK26511.1 - 0.024 14.3 0.1 0.066 12.8 0.0 1.8 2 0 0 2 2 2 0 NACHT domain MobB PF03205.9 KKK26511.1 - 0.042 13.5 0.2 1.3 8.7 0.0 2.8 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 KKK26511.1 - 0.058 13.5 0.2 0.27 11.3 0.0 2.2 3 1 0 3 3 3 0 AAA domain RNA_helicase PF00910.17 KKK26511.1 - 0.084 13.0 0.0 0.17 12.0 0.0 1.6 1 0 0 1 1 1 0 RNA helicase NB-ARC PF00931.17 KKK26511.1 - 0.15 10.9 0.9 0.67 8.7 0.1 2.0 2 0 0 2 2 2 0 NB-ARC domain COX4 PF02936.9 KKK26512.1 - 2.2e-52 176.5 0.4 3.2e-52 176.0 0.2 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV DUF3106 PF11304.3 KKK26512.1 - 1.6 9.1 7.4 0.35 11.2 2.8 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3106) DUF1289 PF06945.8 KKK26512.1 - 4.6 6.7 5.4 6.7 6.2 0.6 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1289) TPR_12 PF13424.1 KKK26513.1 - 2.9e-20 71.9 3.0 2.5e-06 27.3 0.1 5.1 3 2 2 5 5 5 4 Tetratricopeptide repeat TPR_10 PF13374.1 KKK26513.1 - 7.4e-12 44.7 2.4 0.079 12.9 0.0 6.6 6 0 0 6 6 6 2 Tetratricopeptide repeat DUF676 PF05057.9 KKK26513.1 - 3.1e-05 23.3 0.0 0.00013 21.2 0.0 1.9 1 1 1 2 2 2 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 KKK26513.1 - 0.00034 20.2 0.0 0.00066 19.3 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.2 KKK26513.1 - 0.00042 20.2 0.0 0.00083 19.3 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family TPR_2 PF07719.12 KKK26513.1 - 0.0047 16.7 1.4 1.9 8.5 0.2 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat Abhydrolase_5 PF12695.2 KKK26513.1 - 0.0049 16.6 0.0 0.0096 15.6 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family TPR_11 PF13414.1 KKK26513.1 - 0.014 15.0 0.1 1 9.0 0.0 3.1 3 0 0 3 3 3 0 TPR repeat TPR_16 PF13432.1 KKK26513.1 - 0.027 15.1 0.1 1 10.0 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF4518 PF15008.1 KKK26513.1 - 0.034 13.1 0.1 0.063 12.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4518) Lipase_3 PF01764.20 KKK26513.1 - 0.036 13.6 0.0 0.079 12.5 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) TPR_1 PF00515.23 KKK26513.1 - 0.08 12.5 1.3 2.1 8.1 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat tRNA-synt_2 PF00152.15 KKK26514.1 - 1.1e-69 234.7 0.0 1.7e-69 234.1 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) DUF2156 PF09924.4 KKK26514.1 - 9.1e-18 64.0 0.0 1.3e-17 63.5 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2156) tRNA_anti-codon PF01336.20 KKK26514.1 - 0.0013 18.5 0.0 0.0028 17.4 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 KKK26514.1 - 0.0035 16.5 0.6 1.4 8.0 0.1 2.5 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) Acetyltransf_6 PF13480.1 KKK26514.1 - 0.022 14.7 0.9 0.086 12.8 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Tubulin PF00091.20 KKK26515.1 - 1.4e-70 237.4 0.0 2e-70 236.9 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 KKK26515.1 - 7e-49 165.0 0.1 1.7e-48 163.8 0.0 1.7 2 0 0 2 2 2 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 KKK26515.1 - 0.002 17.6 0.0 0.0047 16.4 0.0 1.6 1 0 0 1 1 1 1 Tubulin domain E1-E2_ATPase PF00122.15 KKK26517.1 - 7.9e-62 208.2 9.0 7.9e-62 208.2 6.2 2.1 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 KKK26517.1 - 6.5e-22 79.0 0.0 9.9e-21 75.1 0.0 2.7 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KKK26517.1 - 5.4e-12 46.2 0.0 1.1e-11 45.2 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KKK26517.1 - 9.8e-11 40.9 0.0 2.4e-10 39.7 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 KKK26517.1 - 0.0016 18.1 0.7 0.0029 17.2 0.1 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase EF-hand_4 PF12763.2 KKK26518.1 - 7e-37 125.3 0.0 1.7e-14 53.4 0.0 3.6 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.1 KKK26518.1 - 3.3e-11 43.1 0.0 8.2e-06 25.8 0.0 4.0 3 2 1 4 4 4 3 EF-hand domain pair EF-hand_1 PF00036.27 KKK26518.1 - 4.7e-09 34.8 0.0 0.0016 17.5 0.0 5.2 6 0 0 6 6 6 2 EF hand EF-hand_6 PF13405.1 KKK26518.1 - 1.4e-07 30.8 0.2 0.82 9.7 0.0 5.9 6 0 0 6 6 6 1 EF-hand domain UBA PF00627.26 KKK26518.1 - 1.5e-07 31.0 0.0 3.1e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain EF-hand_8 PF13833.1 KKK26518.1 - 9.2e-05 21.9 0.1 0.0083 15.7 0.0 3.6 4 0 0 4 4 4 1 EF-hand domain pair TPR_MLP1_2 PF07926.7 KKK26518.1 - 0.021 14.5 25.4 0.021 14.5 8.3 2.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein GAS PF13851.1 KKK26518.1 - 0.069 12.3 23.2 0.029 13.5 6.5 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Myosin_tail_1 PF01576.14 KKK26518.1 - 0.11 10.2 25.2 0.21 9.2 17.5 1.4 1 0 0 1 1 1 0 Myosin tail U3_assoc_6 PF08640.6 KKK26518.1 - 0.11 12.2 0.5 0.24 11.1 0.4 1.5 1 0 0 1 1 1 0 U3 small nucleolar RNA-associated protein 6 Spc7 PF08317.6 KKK26518.1 - 0.26 9.8 24.3 0.18 10.4 5.7 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein IncA PF04156.9 KKK26518.1 - 0.34 10.4 24.4 0.049 13.2 13.5 1.9 1 1 1 2 2 2 0 IncA protein FUSC PF04632.7 KKK26518.1 - 0.94 7.8 8.5 1.7 6.9 5.9 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family CtIP_N PF10482.4 KKK26518.1 - 1.5 8.6 11.2 0.16 11.7 4.6 1.7 2 0 0 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain ADIP PF11559.3 KKK26518.1 - 3.2 7.6 27.0 0.37 10.6 6.0 2.5 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Mod_r PF07200.8 KKK26518.1 - 5.5 6.8 20.4 0.14 12.0 7.9 2.4 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Kelch_2 PF07646.10 KKK26519.1 - 0.058 13.1 0.0 0.19 11.5 0.0 1.8 1 0 0 1 1 1 0 Kelch motif tRNA_U5-meth_tr PF05958.6 KKK26520.1 - 2.2e-11 43.0 0.0 3.9e-05 22.5 0.0 2.2 2 0 0 2 2 2 2 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.1 KKK26520.1 - 0.00026 20.6 0.0 0.00078 19.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain TRAM PF01938.15 KKK26520.1 - 0.00063 19.4 0.2 0.0016 18.1 0.2 1.6 1 0 0 1 1 1 1 TRAM domain Methyltransf_15 PF09445.5 KKK26520.1 - 0.13 11.7 0.0 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase PrmA PF06325.8 KKK26520.1 - 0.21 10.6 0.0 0.34 9.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Ribosomal_S5_C PF03719.10 KKK26521.1 - 6.5e-22 76.5 0.0 2.1e-21 74.9 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.15 KKK26521.1 - 5.9e-09 35.5 1.0 2.5e-08 33.5 0.0 2.4 2 1 1 3 3 3 1 Ribosomal protein S5, N-terminal domain DASH_Dad3 PF08656.5 KKK26522.1 - 1.7e-26 91.6 3.5 2.6e-26 91.1 2.3 1.4 1 1 0 1 1 1 1 DASH complex subunit Dad3 Pkinase PF00069.20 KKK26523.1 - 2.2e-70 236.8 0.0 3.5e-70 236.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK26523.1 - 7.4e-30 103.8 0.0 1.6e-28 99.4 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KKK26523.1 - 2.3e-06 26.8 0.1 0.15 11.0 0.0 3.0 2 1 1 3 3 3 2 Kinase-like Kdo PF06293.9 KKK26523.1 - 0.026 13.5 0.0 0.046 12.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KKK26523.1 - 0.13 11.9 0.0 6.8 6.3 0.0 2.4 1 1 1 2 2 2 0 Phosphotransferase enzyme family Lactonase PF10282.4 KKK26524.1 - 7.5e-83 278.4 0.0 1e-82 278.0 0.0 1.1 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller He_PIG PF05345.7 KKK26524.1 - 0.12 12.4 6.3 0.34 10.9 0.4 3.1 2 1 0 2 2 2 0 Putative Ig domain Cullin PF00888.17 KKK26525.1 - 1.6e-46 159.0 0.0 6.4e-46 157.0 0.0 1.9 2 0 0 2 2 2 1 Cullin family Pkr1 PF08636.5 KKK26525.1 - 6.8e-34 115.7 5.7 1.6e-33 114.5 4.0 1.7 1 0 0 1 1 1 1 ER protein Pkr1 APC2 PF08672.6 KKK26525.1 - 4.1e-23 81.4 0.0 9.9e-23 80.1 0.0 1.7 1 0 0 1 1 1 1 Anaphase promoting complex (APC) subunit 2 Calreticulin PF00262.13 KKK26525.1 - 0.076 11.6 0.2 0.12 10.9 0.1 1.2 1 0 0 1 1 1 0 Calreticulin family Mito_fiss_reg PF05308.6 KKK26525.1 - 1.3 8.3 7.8 3.1 7.1 5.4 1.6 1 0 0 1 1 1 0 Mitochondrial fission regulator GFA PF04828.9 KKK26526.1 - 0.044 13.7 0.1 0.12 12.3 0.1 1.7 1 0 0 1 1 1 0 Glutathione-dependent formaldehyde-activating enzyme AAA_12 PF13087.1 KKK26527.1 - 5.3e-41 140.2 0.0 9.7e-41 139.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KKK26527.1 - 8.8e-29 100.7 0.3 4.2e-28 98.5 0.2 2.2 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KKK26527.1 - 6.4e-08 32.2 0.0 8.9e-07 28.5 0.0 2.6 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 KKK26527.1 - 2.9e-06 26.9 1.7 0.0026 17.3 0.1 2.9 3 0 0 3 3 3 2 AAA domain DUF2075 PF09848.4 KKK26527.1 - 3.7e-05 22.8 0.1 0.1 11.5 0.0 2.5 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) ResIII PF04851.10 KKK26527.1 - 0.00025 20.9 0.0 0.0006 19.6 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.13 KKK26527.1 - 0.00053 19.5 0.3 0.57 9.6 0.0 3.1 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.1 KKK26527.1 - 0.0032 17.5 0.0 0.009 16.1 0.0 1.8 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain zf-CCCH PF00642.19 KKK26527.1 - 0.57 9.9 5.2 0.099 12.3 0.8 1.9 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C2H2 PF00096.21 KKK26529.1 - 5.3e-05 23.3 2.7 0.18 12.2 0.3 3.7 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KKK26529.1 - 8.9e-05 22.5 2.1 0.089 13.1 0.0 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KKK26529.1 - 0.019 15.2 0.0 0.053 13.8 0.0 1.8 1 0 0 1 1 1 0 Zinc-finger double domain zf-C2H2_6 PF13912.1 KKK26529.1 - 6 6.9 8.6 9 6.3 0.1 2.8 3 0 0 3 3 3 0 C2H2-type zinc finger F-box-like PF12937.2 KKK26530.1 - 0.00076 19.1 0.1 0.003 17.2 0.1 2.1 1 0 0 1 1 1 1 F-box-like F-box-like_2 PF13013.1 KKK26530.1 - 0.064 12.9 0.1 0.17 11.6 0.1 1.6 1 0 0 1 1 1 0 F-box-like domain GTP_EFTU PF00009.22 KKK26531.1 - 2.1e-09 37.1 0.0 5e-09 35.8 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.12 KKK26531.1 - 0.00085 18.9 0.1 0.015 14.8 0.0 2.2 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein ABC_tran PF00005.22 KKK26531.1 - 0.039 14.2 0.2 0.082 13.2 0.1 1.5 1 0 0 1 1 1 0 ABC transporter ImcF-related_N PF14331.1 KKK26531.1 - 0.19 10.5 0.1 0.52 9.1 0.0 1.6 2 0 0 2 2 2 0 ImcF-related N-terminal domain zf-C2H2_jaz PF12171.3 KKK26532.1 - 6.2e-08 32.5 0.1 1.1e-07 31.8 0.1 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KKK26532.1 - 6.3e-06 26.2 0.2 1.1e-05 25.4 0.1 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2 PF00096.21 KKK26532.1 - 0.0016 18.6 0.4 0.0031 17.7 0.3 1.5 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_2 PF12756.2 KKK26532.1 - 0.042 13.9 0.3 0.24 11.5 0.0 2.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) MAP7 PF05672.6 KKK26532.1 - 0.57 9.5 29.0 1.6 8.1 0.8 2.2 2 0 0 2 2 2 0 MAP7 (E-MAP-115) family CAF-1_p150 PF11600.3 KKK26532.1 - 2.8 7.2 25.7 1.4 8.1 13.2 2.3 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal TFIID-18kDa PF02269.11 KKK26533.1 - 5e-32 109.5 0.5 7.4e-31 105.8 0.2 2.3 2 0 0 2 2 2 1 Transcription initiation factor IID, 18kD subunit F-box-like PF12937.2 KKK26534.1 - 3.1e-05 23.6 0.0 5.7e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KKK26534.1 - 4.3e-05 23.0 1.3 0.00014 21.3 0.0 2.1 2 0 0 2 2 2 1 F-box domain F-box-like_2 PF13013.1 KKK26534.1 - 0.06 13.0 0.4 0.097 12.3 0.0 1.5 2 0 0 2 2 2 0 F-box-like domain TP_methylase PF00590.15 KKK26536.1 - 1.2e-21 77.3 0.1 2.1e-21 76.6 0.1 1.4 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Sulfotransfer_3 PF13469.1 KKK26537.1 - 0.00017 22.5 0.8 0.00024 22.0 0.4 1.4 1 1 0 1 1 1 1 Sulfotransferase family Clat_adaptor_s PF01217.15 KKK26538.1 - 5.9e-51 171.9 3.0 3.6e-50 169.3 2.1 1.8 1 1 0 1 1 1 1 Clathrin adaptor complex small chain Arylsulfotran_2 PF14269.1 KKK26539.1 - 3.7e-56 190.4 7.7 6.2e-56 189.7 5.3 1.3 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.6 KKK26539.1 - 3.7e-21 75.2 8.0 6.3e-20 71.1 5.5 2.3 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) Mmp37 PF09139.6 KKK26540.1 - 2.2e-140 467.3 0.0 2.7e-140 467.1 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial matrix Mmp37 BIR PF00653.16 KKK26541.1 - 2.9e-41 139.7 6.4 8.1e-22 77.4 0.1 2.5 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain BACK PF07707.10 KKK26542.1 - 0.052 13.3 0.0 6.4 6.6 0.0 2.1 1 1 1 2 2 2 0 BTB And C-terminal Kelch SAP PF02037.22 KKK26543.1 - 4.2e-10 38.8 0.2 8.5e-10 37.8 0.2 1.5 1 0 0 1 1 1 1 SAP domain RRM_5 PF13893.1 KKK26543.1 - 0.12 12.2 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pkinase PF00069.20 KKK26544.1 - 1.3e-31 109.7 0.0 6.1e-31 107.5 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK26544.1 - 5.1e-12 45.4 0.0 1.2e-05 24.5 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase DUF500 PF04366.7 KKK26545.1 - 8.1e-45 151.3 0.0 1.6e-44 150.4 0.0 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF500) Flavodoxin_1 PF00258.20 KKK26546.1 - 9.1e-34 116.5 0.0 1.8e-33 115.5 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin FAD_binding_1 PF00667.15 KKK26546.1 - 7.1e-30 104.0 0.0 1.1e-29 103.4 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 KKK26546.1 - 1.9e-14 54.1 0.0 6.4e-14 52.4 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.2 KKK26546.1 - 0.001 19.1 0.1 0.077 12.9 0.0 2.8 2 1 1 3 3 3 2 Flavodoxin domain Flavodoxin_3 PF12641.2 KKK26546.1 - 0.0012 18.3 0.0 0.0031 16.9 0.0 1.6 2 0 0 2 2 2 1 Flavodoxin domain ETF PF01012.16 KKK26547.1 - 3.2e-36 124.5 0.3 4.2e-36 124.1 0.2 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain Ribosomal_L20 PF00453.13 KKK26547.1 - 0.019 14.8 0.0 0.03 14.2 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L20 JAB PF01398.16 KKK26548.1 - 1.4e-08 34.4 0.0 3.7e-08 33.0 0.0 1.7 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 KKK26548.1 - 0.0038 17.2 0.4 0.13 12.4 0.3 2.6 1 1 0 1 1 1 1 Maintenance of mitochondrial structure and function TBPIP PF07106.8 KKK26548.1 - 0.019 14.4 0.1 0.036 13.6 0.1 1.3 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) RICTOR_M PF14666.1 KKK26548.1 - 0.11 11.5 0.0 0.19 10.7 0.0 1.3 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, middle domain RNA_pol_3_Rpc31 PF11705.3 KKK26549.1 - 3.7e-56 190.6 7.5 5.1e-56 190.2 5.2 1.2 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 Solute_trans_a PF03619.11 KKK26551.1 - 3.1e-84 282.5 21.2 3.7e-84 282.2 14.7 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha DnaJ PF00226.26 KKK26552.1 - 9.1e-29 98.9 5.5 1e-28 98.8 3.8 1.0 1 0 0 1 1 1 1 DnaJ domain CesA PF11439.3 KKK26552.1 - 0.059 13.2 0.2 0.11 12.4 0.1 1.5 1 1 1 2 2 2 0 Type III secretion system filament chaperone CesA PRAP PF15314.1 KKK26552.1 - 0.1 12.9 1.0 0.14 12.4 0.2 1.6 2 0 0 2 2 2 0 Proline-rich acidic protein 1, pregnancy-specific uterine Epimerase PF01370.16 KKK26553.1 - 1.9e-12 47.1 0.1 2.9e-06 26.8 0.1 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NmrA PF05368.8 KKK26553.1 - 1.4e-08 34.3 0.1 1.9e-08 33.8 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.19 KKK26553.1 - 1.1e-06 28.9 0.1 1.7e-06 28.2 0.1 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 KKK26553.1 - 5.6e-05 23.2 0.1 9.3e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 KKK26553.1 - 0.00014 20.6 0.0 0.0016 17.2 0.0 2.0 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 KKK26553.1 - 0.00018 20.5 0.0 0.0011 17.9 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein Saccharop_dh PF03435.13 KKK26553.1 - 0.0023 16.9 0.1 0.0033 16.4 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase Polysacc_synt_2 PF02719.10 KKK26553.1 - 0.0025 16.7 0.1 0.0035 16.2 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Shikimate_DH PF01488.15 KKK26553.1 - 0.019 15.0 0.0 0.14 12.2 0.0 2.3 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase DXP_reductoisom PF02670.11 KKK26553.1 - 0.16 12.4 0.0 0.26 11.8 0.0 1.3 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Vps5 PF09325.5 KKK26554.1 - 3.3e-16 59.2 1.5 4.9e-16 58.7 1.1 1.1 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.19 KKK26554.1 - 0.00018 21.2 0.1 0.056 13.2 0.0 2.5 1 1 1 2 2 2 2 PX domain GTP_EFTU PF00009.22 KKK26555.1 - 9.4e-55 184.9 0.0 1.4e-54 184.4 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 KKK26555.1 - 1.7e-16 59.8 0.0 5.1e-08 32.6 0.0 2.5 2 0 0 2 2 2 2 Elongation factor G C-terminus EFG_II PF14492.1 KKK26555.1 - 8.3e-12 44.7 0.0 2e-11 43.5 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 KKK26555.1 - 5.4e-05 23.2 0.0 0.0001 22.3 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KKK26555.1 - 0.013 15.4 0.0 0.029 14.3 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase EFG_IV PF03764.13 KKK26555.1 - 0.08 12.5 0.1 0.23 11.0 0.0 1.8 2 0 0 2 2 2 0 Elongation factor G, domain IV FTHFS PF01268.14 KKK26555.1 - 0.26 9.2 0.0 0.38 8.6 0.0 1.1 1 0 0 1 1 1 0 Formate--tetrahydrofolate ligase DUF3446 PF11928.3 KKK26555.1 - 0.64 10.2 11.4 0.035 14.2 2.9 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF3446) ArfGap PF01412.13 KKK26556.1 - 3.8e-31 107.3 0.0 6.7e-31 106.5 0.0 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Abhydrolase_1 PF00561.15 KKK26557.1 - 6.8e-46 156.6 0.0 3.6e-45 154.3 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KKK26557.1 - 2.5e-12 47.1 0.0 1.8e-11 44.3 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KKK26557.1 - 0.00046 19.9 0.0 0.24 11.1 0.0 2.2 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_4 PF08386.5 KKK26557.1 - 0.065 13.1 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein DUF2424 PF10340.4 KKK26557.1 - 0.1 11.2 0.0 0.16 10.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) Glyco_hydro_3 PF00933.16 KKK26559.1 - 9.5e-86 287.4 0.0 1.4e-85 286.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KKK26559.1 - 2e-65 220.5 0.0 1.3e-64 217.8 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KKK26559.1 - 3.2e-22 78.2 0.2 1.8e-21 75.8 0.2 2.2 2 0 0 2 2 2 1 Fibronectin type III-like domain PA14 PF07691.7 KKK26559.1 - 8.3e-14 51.4 0.0 1.7e-13 50.4 0.0 1.5 1 0 0 1 1 1 1 PA14 domain DUF11 PF01345.13 KKK26559.1 - 0.0025 17.8 2.8 0.0041 17.1 1.1 2.0 1 1 1 2 2 2 1 Domain of unknown function DUF11 CARDB PF07705.6 KKK26559.1 - 0.013 15.5 0.1 0.03 14.3 0.1 1.6 1 0 0 1 1 1 0 CARDB DUF2808 PF10989.3 KKK26559.1 - 0.063 12.8 0.0 0.22 11.1 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2808) Tho2 PF11262.3 KKK26560.1 - 3.2e-94 315.3 0.0 4.7e-94 314.7 0.0 1.3 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.3 KKK26560.1 - 2.1e-30 104.3 0.1 7.7e-30 102.5 0.0 2.1 2 0 0 2 2 2 1 Transcription- and export-related complex subunit RRM_1 PF00076.17 KKK26561.1 - 1.7e-22 78.7 0.0 6.4e-11 41.7 0.0 3.2 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KKK26561.1 - 7.9e-15 54.5 0.0 1.1e-08 34.9 0.0 2.5 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KKK26561.1 - 2.2e-07 30.6 0.0 0.025 14.4 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DbpA PF03880.10 KKK26561.1 - 0.092 12.4 0.1 9.5 5.9 0.0 2.4 2 0 0 2 2 2 0 DbpA RNA binding domain API5 PF05918.6 KKK26561.1 - 0.17 10.3 4.2 0.22 9.9 2.9 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Peptidase_S10 PF00450.17 KKK26562.1 - 4.1e-84 283.1 0.3 7.7e-84 282.2 0.2 1.4 1 1 0 1 1 1 1 Serine carboxypeptidase DUF3439 PF11921.3 KKK26562.1 - 0.98 9.1 9.0 0.31 10.7 4.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) HMGL-like PF00682.14 KKK26563.1 - 9.2e-41 140.0 0.0 1.3e-40 139.5 0.0 1.2 1 0 0 1 1 1 1 HMGL-like OSCP PF00213.13 KKK26564.1 - 3.5e-44 150.6 2.9 4.3e-44 150.3 2.0 1.1 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit DUF148 PF02520.12 KKK26564.1 - 0.063 13.0 1.1 0.24 11.1 0.5 2.1 1 1 2 3 3 3 0 Domain of unknown function DUF148 DUF1542 PF07564.6 KKK26564.1 - 6.9 6.7 9.9 3.2 7.8 0.7 3.1 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1542) Glyco_hydro_63 PF03200.11 KKK26565.1 - 1.3e-06 26.6 5.3 5.9e-05 21.1 0.2 3.6 3 1 0 3 3 3 2 Mannosyl oligosaccharide glucosidase Rgp1 PF08737.5 KKK26566.1 - 4.6e-116 388.3 0.0 7.8e-116 387.5 0.0 1.4 1 0 0 1 1 1 1 Rgp1 Arrestin_N PF00339.24 KKK26566.1 - 0.00017 21.4 0.0 0.00044 20.1 0.0 1.6 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 KKK26566.1 - 0.015 15.4 0.0 0.36 10.9 0.0 2.8 2 0 0 2 2 2 0 Arrestin (or S-antigen), C-terminal domain Spo0M PF07070.6 KKK26566.1 - 0.11 11.7 0.0 0.23 10.7 0.0 1.4 1 0 0 1 1 1 0 SpoOM protein Diphthamide_syn PF01866.12 KKK26567.1 - 7.6e-114 380.0 0.0 9e-114 379.8 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein ADIP PF11559.3 KKK26568.1 - 0.011 15.5 1.0 0.016 15.0 0.7 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding SlyX PF04102.7 KKK26568.1 - 0.077 13.3 1.3 0.14 12.5 0.9 1.5 1 0 0 1 1 1 0 SlyX DUF4482 PF14818.1 KKK26568.1 - 0.079 13.6 1.5 0.098 13.3 0.7 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4482) Bromodomain PF00439.20 KKK26569.1 - 2.3e-16 59.4 0.0 1.4e-15 56.9 0.0 2.2 2 0 0 2 2 2 1 Bromodomain WD40 PF00400.27 KKK26570.1 - 5.5e-24 83.1 5.9 9e-05 22.2 0.0 8.5 8 0 0 8 8 8 6 WD domain, G-beta repeat Neugrin PF06413.6 KKK26571.1 - 2.5e-14 53.6 0.3 2.5e-14 53.6 0.2 1.7 2 0 0 2 2 2 1 Neugrin MRP-L20 PF12824.2 KKK26571.1 - 2.1e-05 24.5 5.0 5.4e-05 23.2 3.4 1.8 1 1 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 SPO22 PF08631.5 KKK26572.1 - 2.5e-18 66.1 1.4 1.2e-09 37.6 0.0 2.5 1 1 1 2 2 2 2 Meiosis protein SPO22/ZIP4 like TPR_12 PF13424.1 KKK26572.1 - 0.00077 19.3 0.2 5.5 7.0 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat Abhydrolase_3 PF07859.8 KKK26574.1 - 5.7e-36 124.0 0.1 1.1e-24 87.2 0.0 2.7 3 0 0 3 3 3 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KKK26574.1 - 0.037 13.7 0.0 0.13 11.9 0.0 1.9 1 1 0 1 1 1 0 Alpha/beta hydrolase family CLN3 PF02487.12 KKK26575.1 - 1.1e-100 337.2 15.6 1.3e-98 330.4 10.8 2.3 1 1 0 1 1 1 1 CLN3 protein MFS_1 PF07690.11 KKK26575.1 - 0.00079 18.2 20.6 0.0021 16.8 12.2 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF3184 PF11380.3 KKK26576.1 - 3.1e-20 71.7 0.4 1.1e-11 43.4 0.0 4.0 3 1 0 3 3 3 3 Protein of unknown function (DUF3184) Mob1_phocein PF03637.12 KKK26577.1 - 1.2e-71 239.9 0.0 1.6e-71 239.6 0.0 1.0 1 0 0 1 1 1 1 Mob1/phocein family Abhydrolase_6 PF12697.2 KKK26578.1 - 2.8e-33 115.6 0.0 3.5e-33 115.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KKK26578.1 - 7.9e-22 77.9 0.0 1.4e-21 77.1 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KKK26578.1 - 8.7e-11 41.7 0.0 5.4e-10 39.2 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KKK26578.1 - 2.3e-05 24.1 0.0 4.7e-05 23.1 0.0 1.5 1 1 0 1 1 1 1 Putative lysophospholipase Chlorophyllase2 PF12740.2 KKK26578.1 - 0.0081 15.0 0.0 0.012 14.5 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.6 KKK26578.1 - 0.039 12.7 0.0 0.057 12.2 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase Abhydrolase_4 PF08386.5 KKK26578.1 - 0.13 12.1 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 TAP-like protein AMP-binding PF00501.23 KKK26579.1 - 4e-79 265.9 0.0 6e-79 265.3 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 KKK26579.1 - 1.5e-61 207.4 0.0 2.9e-61 206.5 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein adh_short PF00106.20 KKK26579.1 - 2.5e-34 118.5 5.0 1.4e-30 106.4 1.7 3.0 3 0 0 3 3 3 2 short chain dehydrogenase KR PF08659.5 KKK26579.1 - 1e-16 61.1 2.7 5.1e-13 49.0 1.0 2.5 2 0 0 2 2 2 2 KR domain adh_short_C2 PF13561.1 KKK26579.1 - 9.1e-16 58.3 0.1 1.9e-15 57.3 0.0 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KKK26579.1 - 9.1e-15 54.7 0.0 1.9e-08 34.0 0.0 2.6 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 KKK26579.1 - 5.8e-12 45.7 0.0 1.6e-11 44.3 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.14 KKK26579.1 - 4.8e-08 32.0 0.0 0.001 17.8 0.0 3.2 3 0 0 3 3 3 2 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 KKK26579.1 - 1.1e-05 24.5 0.1 0.0092 14.9 0.0 3.3 3 0 0 3 3 3 1 RmlD substrate binding domain AMP-binding_C PF13193.1 KKK26579.1 - 3.7e-05 24.5 0.4 0.00028 21.7 0.1 2.7 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain NAD_binding_10 PF13460.1 KKK26579.1 - 0.00012 22.1 2.5 0.03 14.3 0.5 4.0 4 1 0 4 4 3 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 KKK26579.1 - 0.048 13.4 1.7 0.13 12.0 1.2 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase THF_DHG_CYH_C PF02882.14 KKK26579.1 - 0.083 11.9 0.0 0.23 10.5 0.0 1.7 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain ApbA PF02558.11 KKK26579.1 - 0.1 12.0 0.1 0.21 11.0 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Aminotran_5 PF00266.14 KKK26580.1 - 4.4e-22 78.3 0.0 2.3e-18 66.0 0.0 3.1 1 1 0 1 1 1 1 Aminotransferase class-V 2OG-FeII_Oxy_4 PF13661.1 KKK26580.1 - 0.044 13.4 0.0 3.7 7.2 0.0 2.5 2 0 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily Abhydrolase_6 PF12697.2 KKK26581.1 - 8.7e-23 81.3 0.0 1e-22 81.1 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KKK26581.1 - 2.1e-09 37.2 0.0 2.6e-09 36.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KKK26581.1 - 0.01 15.4 0.0 2.1 7.8 0.0 2.2 2 0 0 2 2 2 0 alpha/beta hydrolase fold Lipase_2 PF01674.13 KKK26581.1 - 0.14 11.4 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 Lipase (class 2) Zip PF02535.17 KKK26582.1 - 3.8e-48 164.1 2.1 7.4e-48 163.1 1.5 1.4 1 1 0 1 1 1 1 ZIP Zinc transporter DNA_pol_phi PF04931.8 KKK26584.1 - 8e-77 258.7 12.4 1.4e-76 257.9 8.6 1.4 1 0 0 1 1 1 1 DNA polymerase phi Apo-CII PF05355.6 KKK26584.1 - 0.035 13.9 0.2 0.14 12.0 0.1 2.1 1 0 0 1 1 1 0 Apolipoprotein C-II Nop14 PF04147.7 KKK26584.1 - 0.036 11.9 17.9 0.069 11.0 12.4 1.5 1 0 0 1 1 1 0 Nop14-like family DUF3510 PF12022.3 KKK26584.1 - 0.053 13.6 1.8 4.2 7.4 0.0 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF3510) Sld5 PF05916.6 KKK26585.1 - 2.2e-11 43.9 0.7 4.4e-11 43.0 0.5 1.5 1 0 0 1 1 1 1 GINS complex protein FlaF PF07309.6 KKK26585.1 - 0.063 13.1 1.9 0.11 12.4 1.3 1.3 1 0 0 1 1 1 0 Flagellar protein FlaF ATG16 PF08614.6 KKK26585.1 - 0.57 9.9 5.2 0.11 12.3 0.9 1.7 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Mlf1IP PF10248.4 KKK26585.1 - 7.9 6.0 6.9 1.2 8.7 0.3 2.1 1 1 0 2 2 2 0 Myelodysplasia-myeloid leukemia factor 1-interacting protein Rhodanese PF00581.15 KKK26586.1 - 9e-13 48.5 0.0 2.2e-12 47.2 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain WD40 PF00400.27 KKK26587.1 - 1.7e-26 91.0 19.7 2.3e-08 33.6 0.6 10.7 9 1 0 9 9 9 7 WD domain, G-beta repeat Nucleoporin_N PF08801.6 KKK26587.1 - 0.0083 14.9 2.8 0.63 8.7 0.0 3.6 2 1 0 3 3 3 2 Nup133 N terminal like PIP5K PF01504.13 KKK26588.1 - 2.6e-59 200.3 0.1 6e-59 199.1 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.19 KKK26588.1 - 1.5e-26 93.1 0.0 2.2e-26 92.5 0.0 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.16 KKK26588.1 - 1.4e-14 53.7 4.0 1.4e-14 53.7 2.8 1.9 2 0 0 2 2 2 1 FYVE zinc finger XPC-binding PF09280.6 KKK26588.1 - 0.093 12.2 0.5 0.23 10.9 0.3 1.6 1 0 0 1 1 1 0 XPC-binding domain PK PF00224.16 KKK26589.1 - 4e-174 578.1 2.2 5e-174 577.8 1.5 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.11 KKK26589.1 - 1.7e-31 108.2 0.0 4.4e-31 106.8 0.0 1.7 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.9 KKK26589.1 - 4e-05 22.6 0.8 9.5e-05 21.3 0.6 1.7 1 1 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.20 KKK26589.1 - 0.006 15.5 0.1 0.12 11.1 0.0 2.2 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain Cellulase PF00150.13 KKK26590.1 - 2.6e-55 187.6 0.6 3.3e-55 187.2 0.4 1.0 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) SUR7 PF06687.7 KKK26591.1 - 3.2e-55 186.9 7.0 3.8e-55 186.7 4.9 1.1 1 0 0 1 1 1 1 SUR7/PalI family DUF348 PF03990.9 KKK26591.1 - 0.0013 18.2 3.0 0.0023 17.4 2.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF348) Clc-like PF07062.7 KKK26591.1 - 0.009 15.2 3.2 0.015 14.5 2.2 1.3 1 0 0 1 1 1 1 Clc-like DUF1748 PF08520.5 KKK26592.1 - 6.7e-37 124.9 0.1 7.5e-37 124.8 0.1 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) HNH_2 PF13391.1 KKK26593.1 - 3e-09 36.5 0.1 2.2e-07 30.5 0.1 2.5 1 1 0 1 1 1 1 HNH endonuclease Lipase_GDSL PF00657.17 KKK26594.1 - 1.4e-12 47.9 1.6 1.9e-12 47.5 1.1 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase PhrC_PhrF PF11131.3 KKK26594.1 - 0.0088 15.5 0.3 0.018 14.6 0.2 1.5 1 0 0 1 1 1 1 Rap-phr extracellular signalling TPP1 PF10341.4 KKK26595.1 - 0.00087 19.2 0.0 0.0023 17.8 0.0 1.7 1 0 0 1 1 1 1 Shelterin complex subunit, TPP1/ACD Pil1 PF13805.1 KKK26596.1 - 6.8e-152 504.2 0.6 8.4e-152 503.9 0.4 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 HAD_2 PF13419.1 KKK26596.1 - 0.052 13.7 0.1 0.09 12.9 0.1 1.3 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase FAM92 PF06730.6 KKK26596.1 - 0.063 12.6 4.0 0.047 13.0 1.6 1.6 2 0 0 2 2 2 0 FAM92 protein V_ATPase_I PF01496.14 KKK26596.1 - 0.16 9.7 1.2 0.23 9.2 0.8 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family bZIP_2 PF07716.10 KKK26597.1 - 6.8e-13 48.2 13.5 1.5e-12 47.1 9.4 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 KKK26597.1 - 3.7e-05 23.5 15.6 7.3e-05 22.6 10.4 1.8 1 1 1 2 2 2 2 bZIP transcription factor Herpes_BLRF2 PF05812.7 KKK26597.1 - 0.00045 20.0 1.5 0.00058 19.6 0.2 1.8 1 1 1 2 2 2 1 Herpesvirus BLRF2 protein DUF4094 PF13334.1 KKK26597.1 - 0.016 15.5 1.2 0.035 14.4 0.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) DUF3552 PF12072.3 KKK26597.1 - 0.067 12.3 8.7 0.088 12.0 6.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Fungal_trans PF04082.13 KKK26598.1 - 5.3e-25 87.7 0.1 5.3e-25 87.7 0.1 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK26598.1 - 8e-05 22.4 9.5 0.00014 21.7 6.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain XPG_N PF00752.12 KKK26599.1 - 1.8e-36 124.4 0.1 5.6e-36 122.8 0.0 1.9 2 0 0 2 2 2 1 XPG N-terminal domain XPG_I PF00867.13 KKK26599.1 - 1.1e-24 86.3 0.0 3.1e-24 84.8 0.0 1.9 1 0 0 1 1 1 1 XPG I-region UIM PF02809.15 KKK26599.1 - 1.9e-05 23.8 0.4 1.9e-05 23.8 0.2 3.7 4 0 0 4 4 4 2 Ubiquitin interaction motif 5_3_exonuc PF01367.15 KKK26599.1 - 0.0012 19.0 0.0 0.0042 17.2 0.0 1.9 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold XPG_I_2 PF12813.2 KKK26599.1 - 0.0065 15.9 0.0 0.014 14.8 0.0 1.5 1 0 0 1 1 1 1 XPG domain containing Transposase_20 PF02371.11 KKK26599.1 - 0.054 13.5 0.0 0.14 12.3 0.0 1.6 1 0 0 1 1 1 0 Transposase IS116/IS110/IS902 family AA_permease_2 PF13520.1 KKK26600.1 - 6.2e-43 146.9 50.9 7.8e-43 146.5 35.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KKK26600.1 - 1.5e-23 82.9 47.8 1.8e-23 82.6 33.2 1.0 1 0 0 1 1 1 1 Amino acid permease Glyoxalase_2 PF12681.2 KKK26601.1 - 1.5e-10 41.6 0.1 1.9e-10 41.2 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 KKK26601.1 - 6.2e-05 22.9 0.0 0.00021 21.2 0.0 1.7 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily ADH_N PF08240.7 KKK26602.1 - 2.8e-24 84.9 0.1 5.2e-24 84.1 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KKK26602.1 - 4.4e-15 55.3 0.0 9.3e-15 54.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 KKK26602.1 - 3.3e-05 23.1 0.1 6.9e-05 22.0 0.0 1.5 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 KKK26602.1 - 0.00077 19.0 0.2 0.0013 18.2 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.13 KKK26602.1 - 0.0089 15.7 0.1 0.018 14.6 0.1 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 KKK26602.1 - 0.0092 15.8 0.0 0.016 15.0 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ThiF PF00899.16 KKK26602.1 - 0.42 10.4 1.9 0.84 9.4 1.0 1.7 2 0 0 2 2 2 0 ThiF family Fungal_trans PF04082.13 KKK26603.1 - 3.6e-26 91.5 0.1 6.6e-26 90.7 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK26603.1 - 6.5e-09 35.5 11.8 1.1e-08 34.8 8.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cep57_CLD_2 PF14197.1 KKK26603.1 - 0.038 13.9 1.0 0.07 13.0 0.7 1.4 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 Lzipper-MIP1 PF14389.1 KKK26603.1 - 0.063 13.3 1.2 0.14 12.2 0.1 2.0 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 Pox_A_type_inc PF04508.7 KKK26603.1 - 0.12 12.2 7.9 0.3 10.9 5.5 1.7 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat Ank_2 PF12796.2 KKK26605.1 - 1.8e-74 246.1 7.7 3.2e-16 59.4 0.2 7.1 3 1 2 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 KKK26605.1 - 2e-58 191.4 24.5 1.9e-06 27.3 0.2 14.1 13 0 0 13 13 13 11 Ankyrin repeat Ank_4 PF13637.1 KKK26605.1 - 2.3e-51 171.3 11.3 2.2e-13 50.3 0.1 9.5 5 2 5 10 10 10 9 Ankyrin repeats (many copies) Ank_5 PF13857.1 KKK26605.1 - 1.1e-49 165.2 17.2 1.6e-08 34.4 0.1 11.5 4 2 7 11 11 11 11 Ankyrin repeats (many copies) Ank_3 PF13606.1 KKK26605.1 - 3.6e-39 128.8 10.8 1.4e-05 24.8 0.4 13.4 13 0 0 13 13 13 8 Ankyrin repeat NACHT PF05729.7 KKK26605.1 - 7.3e-06 25.7 0.0 2.4e-05 24.0 0.0 1.9 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KKK26605.1 - 6.6e-05 22.9 0.4 0.00023 21.2 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KKK26605.1 - 0.00014 21.9 0.0 0.00055 20.0 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 KKK26605.1 - 0.0073 16.5 0.0 0.027 14.6 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Shigella_OspC PF06128.6 KKK26605.1 - 0.015 14.8 0.0 4.7 6.6 0.0 3.6 3 1 0 3 3 3 0 Shigella flexneri OspC protein Rab3-GTPase_cat PF13890.1 KKK26605.1 - 0.022 14.1 0.2 0.042 13.2 0.1 1.4 1 0 0 1 1 1 0 Rab3 GTPase-activating protein catalytic subunit DUF2075 PF09848.4 KKK26605.1 - 0.029 13.3 0.0 0.086 11.7 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) ZZ PF00569.12 KKK26605.1 - 0.064 12.8 10.0 0.13 11.8 6.9 1.4 1 0 0 1 1 1 0 Zinc finger, ZZ type HipA_C PF07804.7 KKK26605.1 - 0.067 13.3 0.0 0.35 10.9 0.0 2.3 1 0 0 1 1 1 0 HipA-like C-terminal domain Strep_67kDa_ant PF06100.6 KKK26606.1 - 7.3e-106 354.4 0.0 8.7e-106 354.2 0.0 1.0 1 0 0 1 1 1 1 Streptococcal 67 kDa myosin-cross-reactive antigen like family NAD_binding_8 PF13450.1 KKK26606.1 - 1.8e-05 24.6 0.2 4.6e-05 23.3 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KKK26606.1 - 0.0085 15.0 0.1 0.12 11.2 0.1 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KKK26606.1 - 0.068 12.9 0.2 0.19 11.4 0.0 1.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding MFS_1 PF07690.11 KKK26607.1 - 1.4e-39 135.8 43.9 1.8e-37 128.8 20.9 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KKK26607.1 - 3.5e-15 55.5 14.8 4.1e-15 55.3 10.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KKK26608.1 - 1.1e-18 67.0 50.7 1.2e-18 66.9 34.6 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Pyr_redox_3 PF13738.1 KKK26609.1 - 5.3e-23 82.1 0.0 7.9e-23 81.5 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KKK26609.1 - 6.6e-17 60.9 0.2 3.1e-15 55.3 0.0 2.6 2 2 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 KKK26609.1 - 6.1e-11 41.8 0.1 9e-10 37.9 0.0 2.5 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 KKK26609.1 - 5e-08 32.8 3.8 2.2e-07 30.8 0.2 3.2 3 1 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KKK26609.1 - 8e-07 29.1 0.0 2.1e-06 27.7 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KKK26609.1 - 2.7e-05 23.2 0.0 0.0092 14.9 0.0 2.6 3 0 0 3 3 3 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KKK26609.1 - 0.00017 20.6 0.4 0.0016 17.4 0.0 2.6 3 0 0 3 3 3 1 Lycopene cyclase protein Pyr_redox PF00070.22 KKK26609.1 - 0.00042 20.6 0.4 1.1 9.6 0.0 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KKK26609.1 - 0.001 18.0 0.0 0.0019 17.1 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 KKK26609.1 - 0.0015 17.6 0.1 0.0015 17.6 0.0 2.0 3 0 0 3 3 3 1 Thi4 family HI0933_like PF03486.9 KKK26609.1 - 0.011 14.1 0.3 0.041 12.3 0.0 1.9 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_9 PF13454.1 KKK26609.1 - 2.1 8.0 6.6 6.4 6.5 0.2 3.9 4 2 0 4 4 4 0 FAD-NAD(P)-binding DUF4034 PF13226.1 KKK26611.1 - 0.04 13.0 0.0 0.045 12.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4034) REF PF05755.7 KKK26611.1 - 0.12 12.1 0.1 0.13 11.9 0.1 1.2 1 0 0 1 1 1 0 Rubber elongation factor protein (REF) APH PF01636.18 KKK26612.1 - 1.1e-11 44.9 0.0 1.2e-09 38.2 0.0 2.8 2 1 0 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.15 KKK26612.1 - 0.0025 17.0 0.0 0.004 16.3 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase Isy1 PF06246.7 KKK26613.1 - 1.2e-77 260.7 0.1 1.4e-77 260.5 0.1 1.1 1 0 0 1 1 1 1 Isy1-like splicing family YolD PF08863.5 KKK26613.1 - 0.01 15.6 0.0 0.018 14.8 0.0 1.4 1 0 0 1 1 1 0 YolD-like protein SH3_1 PF00018.23 KKK26614.1 - 2.8e-11 42.6 0.0 6.3e-11 41.4 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KKK26614.1 - 2e-10 40.0 0.0 3.9e-10 39.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KKK26614.1 - 9.4e-07 28.2 0.0 1.8e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain HMG-CoA_red PF00368.13 KKK26615.1 - 5.3e-154 512.3 7.3 6.7e-154 512.0 5.1 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase HPIH PF13323.1 KKK26615.1 - 2.5e-56 189.6 0.2 4.3e-56 188.8 0.2 1.4 1 0 0 1 1 1 1 N-terminal domain with HPIH motif Sterol-sensing PF12349.3 KKK26615.1 - 1.9e-13 50.1 3.0 5.2e-13 48.7 2.1 1.8 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.13 KKK26615.1 - 2.2e-08 32.5 5.3 4.1e-08 31.6 3.7 1.3 1 0 0 1 1 1 1 Patched family DUF952 PF06108.7 KKK26616.1 - 5.2e-26 90.3 0.0 6.2e-26 90.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF952) IMPDH PF00478.20 KKK26617.1 - 1.4e-129 431.9 2.6 1.7e-129 431.7 1.8 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.23 KKK26617.1 - 8.1e-20 70.3 0.0 1.8e-09 37.1 0.0 2.4 2 0 0 2 2 2 2 CBS domain NMO PF03060.10 KKK26617.1 - 1.4e-06 27.6 2.9 0.011 14.9 2.0 2.5 2 0 0 2 2 2 2 Nitronate monooxygenase FMN_dh PF01070.13 KKK26617.1 - 4.5e-05 22.4 0.5 0.00014 20.8 0.3 1.8 2 0 0 2 2 2 1 FMN-dependent dehydrogenase His_biosynth PF00977.16 KKK26617.1 - 0.00065 19.0 2.4 0.005 16.1 1.7 2.0 1 1 0 1 1 1 1 Histidine biosynthesis protein DUF1273 PF06908.6 KKK26617.1 - 0.065 12.8 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1273) RasGAP_C PF03836.10 KKK26618.1 - 9.2e-49 164.7 4.6 9.2e-49 164.7 3.2 3.0 3 0 0 3 3 3 1 RasGAP C-terminus RasGAP PF00616.14 KKK26618.1 - 8.2e-43 146.3 0.0 3.2e-42 144.4 0.0 2.0 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase CH PF00307.26 KKK26618.1 - 5.7e-10 39.2 0.0 4.9e-09 36.2 0.0 2.6 2 0 0 2 2 2 1 Calponin homology (CH) domain IQ PF00612.22 KKK26618.1 - 8e-07 28.1 52.3 0.33 10.6 0.7 14.4 15 0 0 15 15 15 4 IQ calmodulin-binding motif ENTH PF01417.15 KKK26620.1 - 5.1e-46 155.6 0.1 7.2e-46 155.1 0.1 1.2 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.11 KKK26620.1 - 1.6e-05 23.7 0.0 2.3e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 ANTH domain VHS PF00790.14 KKK26620.1 - 0.044 13.4 0.1 0.076 12.6 0.0 1.4 1 0 0 1 1 1 0 VHS domain NUDIX PF00293.23 KKK26621.1 - 1.7e-12 47.1 0.0 2.8e-10 39.9 0.0 3.0 1 1 0 1 1 1 1 NUDIX domain Ribosomal_S21e PF01249.13 KKK26622.1 - 8.2e-42 141.0 0.1 9.2e-42 140.8 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e tRNA-synt_2d PF01409.15 KKK26623.1 - 3.6e-88 294.9 0.0 4.9e-88 294.4 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) tRNA-synt_2 PF00152.15 KKK26623.1 - 1.2e-06 27.5 0.5 0.00023 20.0 0.0 3.6 4 0 0 4 4 4 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.20 KKK26623.1 - 0.0005 19.6 0.0 0.0012 18.5 0.0 1.5 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_His PF13393.1 KKK26623.1 - 0.063 12.3 0.0 0.14 11.1 0.0 1.5 1 0 0 1 1 1 0 Histidyl-tRNA synthetase HAMP PF00672.20 KKK26624.1 - 1.1e-49 166.4 16.6 8e-10 38.7 0.4 6.9 6 0 0 6 6 6 6 HAMP domain HATPase_c PF02518.21 KKK26624.1 - 4.9e-31 106.7 0.1 1.9e-30 104.8 0.1 2.1 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 KKK26624.1 - 2.5e-28 98.3 0.3 1.5e-26 92.5 0.3 3.0 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.20 KKK26624.1 - 4.5e-16 58.6 0.1 4.5e-16 58.6 0.1 4.4 6 0 0 6 6 6 1 His Kinase A (phospho-acceptor) domain DUF2365 PF10157.4 KKK26624.1 - 0.00083 19.2 15.8 1.6 8.6 0.1 6.9 6 1 0 7 7 7 2 Uncharacterized conserved protein (DUF2365) AAA_13 PF13166.1 KKK26624.1 - 0.027 12.9 30.9 0.057 11.8 2.7 4.1 1 1 2 4 4 4 0 AAA domain NOD PF06816.8 KKK26624.1 - 0.039 13.0 0.1 1.1 8.3 0.0 2.7 2 0 0 2 2 2 0 NOTCH protein PilJ PF13675.1 KKK26624.1 - 0.081 13.2 8.6 10 6.4 0.1 6.0 3 2 4 7 7 7 0 Type IV pili methyl-accepting chemotaxis transducer N-term Scaffolding_pro PF11418.3 KKK26624.1 - 0.43 10.9 9.2 39 4.6 0.0 5.4 5 0 0 5 5 5 0 Phi29 scaffolding protein NAAA-beta PF15508.1 KKK26624.1 - 1.6 9.1 6.7 18 5.7 0.1 5.3 6 2 0 6 6 6 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase Sugar_tr PF00083.19 KKK26625.1 - 2.7e-23 82.2 8.8 3.4e-23 81.9 6.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KKK26625.1 - 5e-15 55.0 12.9 6.4e-15 54.7 8.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 KKK26625.1 - 2.7e-06 26.0 4.7 3e-06 25.8 3.3 1.3 1 0 0 1 1 1 1 MFS/sugar transport protein TRI12 PF06609.8 KKK26625.1 - 9.2e-05 20.8 1.9 0.00012 20.5 1.3 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) PTR2 PF00854.16 KKK26625.1 - 0.45 9.2 3.9 2.7 6.6 0.8 2.0 1 1 1 2 2 2 0 POT family DUF2371 PF10177.4 KKK26625.1 - 2.3 8.0 10.0 0.45 10.3 3.9 1.8 1 1 0 1 1 1 0 Uncharacterised conserved protein (DUF2371) Pyr_redox_2 PF07992.9 KKK26626.1 - 3.7e-06 26.9 0.0 4.2e-05 23.5 0.0 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KKK26626.1 - 0.00088 19.0 0.0 0.013 15.2 0.0 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.19 KKK26626.1 - 0.0019 17.1 0.3 0.0034 16.3 0.2 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KKK26626.1 - 0.01 15.9 0.1 0.036 14.1 0.1 1.8 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KKK26626.1 - 0.091 12.7 0.0 0.25 11.4 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 KKK26626.1 - 0.17 10.7 1.4 0.33 9.8 0.2 2.0 2 1 0 2 2 2 0 Lycopene cyclase protein Lactamase_B PF00753.22 KKK26627.1 - 6.8e-21 74.8 0.6 9.6e-21 74.3 0.4 1.1 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KKK26627.1 - 0.032 13.7 0.1 0.047 13.2 0.1 1.3 1 0 0 1 1 1 0 Beta-lactamase superfamily domain NAD_binding_1 PF00175.16 KKK26628.1 - 1.6e-10 41.4 0.0 3.1e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 KKK26628.1 - 1.1e-08 35.1 0.0 1.8e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Globin PF00042.17 KKK26628.1 - 1.7e-08 34.7 0.1 5.9e-08 33.0 0.0 2.0 3 0 0 3 3 3 1 Globin Protoglobin PF11563.3 KKK26628.1 - 0.00097 18.8 0.0 0.0025 17.4 0.0 1.7 1 1 0 1 1 1 1 Protoglobin NAD_binding_6 PF08030.7 KKK26628.1 - 0.045 13.6 0.0 0.3 10.9 0.0 2.2 2 1 1 3 3 3 0 Ferric reductase NAD binding domain MIP PF00230.15 KKK26629.1 - 1.8e-38 132.2 13.4 1.5e-24 86.7 4.9 2.1 2 0 0 2 2 2 2 Major intrinsic protein CD24 PF14984.1 KKK26629.1 - 0.0097 15.6 0.0 6.5 6.6 0.0 2.7 2 0 0 2 2 2 2 CD24 protein AA_permease_2 PF13520.1 KKK26630.1 - 1.3e-55 188.7 34.9 1.3e-55 188.7 24.2 2.1 2 0 0 2 2 2 2 Amino acid permease Herpes_US9 PF06072.6 KKK26630.1 - 0.71 9.7 4.3 4.9 7.0 0.0 3.7 3 0 0 3 3 3 0 Alphaherpesvirus tegument protein US9 Pneumo_phosprot PF02478.11 KKK26631.1 - 0.96 8.9 7.6 1.3 8.5 5.3 1.1 1 0 0 1 1 1 0 Pneumovirus phosphoprotein Anoctamin PF04547.7 KKK26632.1 - 6.1e-105 351.4 3.5 7.6e-105 351.1 2.4 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel ArabFuran-catal PF09206.6 KKK26633.1 - 5e-162 538.3 21.1 5e-162 538.3 14.6 1.5 2 0 0 2 2 2 1 Alpha-L-arabinofuranosidase B, catalytic AbfB PF05270.8 KKK26633.1 - 3.8e-64 214.7 2.4 5.7e-64 214.1 1.7 1.3 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase B (ABFB) GPI-anchored PF10342.4 KKK26635.1 - 3.9e-20 72.1 3.9 3.9e-20 72.1 2.7 2.3 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF1593 PF07632.6 KKK26636.1 - 1.5e-79 267.0 0.1 2.5e-79 266.2 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1593) Pro-kuma_activ PF09286.6 KKK26637.1 - 2.4e-29 102.2 0.4 5.5e-28 97.8 0.0 2.6 3 0 0 3 3 3 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 KKK26637.1 - 1.2e-06 27.8 0.0 2.2e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Subtilase family FAD_binding_4 PF01565.18 KKK26638.1 - 1.2e-16 60.4 1.8 2.6e-16 59.3 1.2 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KKK26638.1 - 6.1e-07 29.2 0.0 1.7e-06 27.7 0.0 1.8 1 0 0 1 1 1 1 Berberine and berberine like FAD_binding_4 PF01565.18 KKK26639.1 - 5.6e-17 61.5 0.1 1.3e-16 60.3 0.1 1.7 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KKK26639.1 - 6.8e-09 35.4 0.1 1.9e-08 34.1 0.1 1.7 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.5 KKK26639.1 - 0.0094 15.1 0.0 0.014 14.5 0.0 1.2 1 0 0 1 1 1 1 Cytokinin dehydrogenase 1, FAD and cytokinin binding DUF2172 PF09940.4 KKK26640.1 - 0.033 12.5 0.0 0.064 11.6 0.0 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF2172) DUF998 PF06197.8 KKK26641.1 - 2.8 7.2 16.3 0.045 13.0 4.4 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF998) SH3_9 PF14604.1 KKK26642.1 - 6.8e-10 38.3 0.1 1.4e-09 37.3 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KKK26642.1 - 7.8e-10 37.9 0.0 1.5e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 SH3 domain PH PF00169.24 KKK26642.1 - 1.8e-09 37.7 0.0 4.8e-09 36.3 0.0 1.8 1 0 0 1 1 1 1 PH domain SAM_2 PF07647.12 KKK26642.1 - 1.1e-08 34.8 0.1 1.9e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH_11 PF15413.1 KKK26642.1 - 6.7e-06 26.3 0.0 1.5e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain SH3_2 PF07653.12 KKK26642.1 - 1.2e-05 24.7 0.1 2.2e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain PH_8 PF15409.1 KKK26642.1 - 0.069 13.2 0.0 0.19 11.7 0.0 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain zf-MIZ PF02891.15 KKK26643.1 - 3.8e-12 45.5 0.2 7e-12 44.6 0.2 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.3 KKK26643.1 - 0.0014 18.1 0.1 0.0029 17.0 0.0 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Nsp1_C PF05064.8 KKK26645.1 - 1.3e-42 144.1 1.1 1.3e-42 144.1 0.8 1.7 2 0 0 2 2 2 1 Nsp1-like C-terminal region Nucleoporin_FG PF13634.1 KKK26645.1 - 5.4e-07 29.8 41.4 5.4e-07 29.8 28.7 6.5 1 1 4 5 5 3 3 Nucleoporin FG repeat region APG17 PF04108.7 KKK26645.1 - 0.012 14.4 4.2 0.016 13.9 2.9 1.1 1 0 0 1 1 1 0 Autophagy protein Apg17 ParB PF08775.5 KKK26645.1 - 0.013 15.8 0.6 0.013 15.8 0.4 1.7 2 0 0 2 2 2 0 ParB family DUF3584 PF12128.3 KKK26645.1 - 0.11 9.7 8.6 0.16 9.2 5.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) EzrA PF06160.7 KKK26645.1 - 0.18 9.9 9.9 0.12 10.5 1.2 2.0 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA AAA_13 PF13166.1 KKK26645.1 - 0.2 10.0 8.6 0.069 11.5 1.5 2.0 1 1 1 2 2 2 0 AAA domain MscS_porin PF12795.2 KKK26645.1 - 0.23 10.7 13.4 0.64 9.2 1.2 2.2 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain Tropomyosin_1 PF12718.2 KKK26645.1 - 0.26 11.1 9.5 0.077 12.8 4.3 1.7 1 1 0 1 1 1 0 Tropomyosin like Myosin_tail_1 PF01576.14 KKK26645.1 - 0.28 8.8 10.1 0.45 8.1 7.0 1.2 1 0 0 1 1 1 0 Myosin tail APG6 PF04111.7 KKK26645.1 - 0.29 10.1 8.3 0.46 9.4 5.8 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF972 PF06156.8 KKK26645.1 - 0.3 11.4 1.9 1 9.7 0.0 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF972) DUF1664 PF07889.7 KKK26645.1 - 0.89 9.3 4.6 0.72 9.6 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) MCPsignal PF00015.16 KKK26645.1 - 1.2 8.6 7.7 3.1 7.2 1.8 2.2 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF4200 PF13863.1 KKK26645.1 - 1.3 8.9 11.7 0.11 12.4 3.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) DUF342 PF03961.8 KKK26645.1 - 1.5 7.1 6.5 3.4 5.9 0.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF342) BLOC1_2 PF10046.4 KKK26645.1 - 1.7 8.8 4.1 8.8 6.5 0.2 2.4 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FlaC_arch PF05377.6 KKK26645.1 - 2.5 8.0 3.9 8 6.4 0.1 2.7 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) IFT57 PF10498.4 KKK26645.1 - 3.5 6.2 12.2 2.7 6.6 2.7 2.0 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 Spc7 PF08317.6 KKK26645.1 - 3.5 6.1 12.3 1.9 7.0 1.1 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein Laminin_II PF06009.7 KKK26645.1 - 4.4 7.0 8.6 9.4 5.9 0.4 2.6 1 1 2 3 3 3 0 Laminin Domain II ERM PF00769.14 KKK26645.1 - 6.9 6.1 12.0 20 4.5 8.3 1.7 1 1 0 1 1 1 0 Ezrin/radixin/moesin family Fib_alpha PF08702.5 KKK26645.1 - 7.7 6.6 6.8 6.5 6.8 0.7 2.4 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family CENP-Q PF13094.1 KKK26645.1 - 8 6.4 9.8 20 5.1 6.4 1.8 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit IncA PF04156.9 KKK26645.1 - 9.2 5.8 11.3 28 4.2 7.8 1.8 1 1 0 1 1 1 0 IncA protein IATP PF04568.7 KKK26646.1 - 2.1e-25 88.6 0.5 2.4e-25 88.4 0.4 1.0 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP Atg14 PF10186.4 KKK26646.1 - 0.0086 15.0 0.6 0.0086 15.0 0.4 1.0 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 14-3-3 PF00244.15 KKK26647.1 - 1.9e-115 383.9 6.3 2.2e-115 383.7 4.3 1.0 1 0 0 1 1 1 1 14-3-3 protein DUF885 PF05960.6 KKK26647.1 - 0.65 9.0 4.8 0.12 11.5 0.9 1.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF885) Metallophos PF00149.23 KKK26648.1 - 1.5e-06 27.7 7.0 1.3e-05 24.7 4.8 2.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Nucleoplasmin PF03066.10 KKK26648.1 - 0.021 14.3 12.5 0.19 11.2 3.0 2.2 2 0 0 2 2 2 0 Nucleoplasmin SAPS PF04499.10 KKK26648.1 - 0.072 11.7 0.4 0.099 11.2 0.3 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein FAM176 PF14851.1 KKK26648.1 - 0.39 10.3 6.9 0.85 9.2 0.1 2.3 2 0 0 2 2 2 0 FAM176 family RR_TM4-6 PF06459.7 KKK26648.1 - 0.42 10.4 8.5 0.65 9.8 5.9 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 TFIIF_alpha PF05793.7 KKK26648.1 - 0.57 8.4 13.4 0.42 8.9 2.1 2.1 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Sigma70_ner PF04546.8 KKK26648.1 - 9.4 5.7 16.2 4.9 6.7 3.9 2.2 2 0 0 2 2 2 0 Sigma-70, non-essential region Complex1_LYR_1 PF13232.1 KKK26649.1 - 7.3e-05 22.8 0.4 0.00019 21.5 0.3 1.7 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 KKK26649.1 - 0.0015 18.2 0.6 0.0036 17.0 0.4 1.7 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Cytotoxic PF09000.5 KKK26649.1 - 0.086 12.8 0.1 0.23 11.5 0.1 1.7 1 0 0 1 1 1 0 Cytotoxic Ank_4 PF13637.1 KKK26650.1 - 2.1e-15 56.7 1.4 2.2e-10 40.7 0.1 4.5 3 1 1 4 4 4 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 KKK26650.1 - 2e-07 31.2 0.3 0.00098 19.4 0.0 3.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KKK26650.1 - 1.7e-06 28.0 3.1 0.00018 21.6 0.0 3.7 3 1 0 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 KKK26650.1 - 5.6e-05 22.9 0.7 0.016 15.3 0.0 4.0 4 0 0 4 4 4 1 Ankyrin repeat KilA-N PF04383.8 KKK26650.1 - 0.0047 16.5 0.3 0.029 14.0 0.2 2.2 1 1 0 1 1 1 1 KilA-N domain Baculo_PEP_C PF04513.7 KKK26650.1 - 0.011 15.5 1.1 0.019 14.8 0.2 1.7 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Ank PF00023.25 KKK26650.1 - 0.025 14.3 2.3 0.24 11.2 0.1 3.3 3 0 0 3 3 3 0 Ankyrin repeat Myb_DNA-bind_6 PF13921.1 KKK26651.1 - 0.034 14.2 0.1 0.095 12.8 0.1 1.8 1 0 0 1 1 1 0 Myb-like DNA-binding domain ResIII PF04851.10 KKK26652.1 - 5.5e-24 85.0 0.0 9.8e-23 80.9 0.0 2.8 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 KKK26652.1 - 8.8e-15 54.3 0.0 2.3e-14 52.9 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KKK26652.1 - 1.1e-12 47.7 0.0 6.3e-12 45.3 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF2075 PF09848.4 KKK26652.1 - 0.006 15.6 0.0 0.011 14.7 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Sugar_tr PF00083.19 KKK26653.1 - 2.3e-36 125.3 24.2 6.3e-36 123.9 16.8 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KKK26653.1 - 1.2e-28 99.8 53.7 3e-27 95.2 23.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily PGAP1 PF07819.8 KKK26654.1 - 1.1e-84 283.5 0.0 1.9e-84 282.7 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 KKK26654.1 - 6.2e-09 35.7 0.0 1.2e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KKK26654.1 - 3.4e-06 27.0 0.1 7.8e-06 25.9 0.1 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KKK26654.1 - 0.00071 19.1 0.0 0.0016 18.0 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF676 PF05057.9 KKK26654.1 - 0.0023 17.2 0.0 0.0043 16.3 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Esterase PF00756.15 KKK26654.1 - 0.0052 16.2 0.0 0.0093 15.4 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Lipase_3 PF01764.20 KKK26654.1 - 0.051 13.1 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) LCAT PF02450.10 KKK26654.1 - 0.072 12.0 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase FAD_binding_3 PF01494.14 KKK26655.1 - 2.1e-20 73.0 0.0 3e-20 72.5 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 KKK26655.1 - 1.1e-09 37.6 1.3 0.00038 19.4 0.3 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 KKK26655.1 - 7.5e-07 29.4 0.3 3.5e-05 24.1 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KKK26655.1 - 1e-06 27.8 0.8 1e-06 27.8 0.6 1.6 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 KKK26655.1 - 4.1e-06 26.7 0.1 1.2e-05 25.1 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KKK26655.1 - 6.2e-06 26.2 0.4 1.8e-05 24.7 0.3 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KKK26655.1 - 7.2e-06 24.7 1.0 0.00028 19.4 0.1 2.1 2 0 0 2 2 2 1 HI0933-like protein Lycopene_cycl PF05834.7 KKK26655.1 - 4.3e-05 22.6 0.7 0.0091 14.9 0.2 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein GIDA PF01134.17 KKK26655.1 - 8.5e-05 21.5 0.1 0.00025 20.0 0.0 1.7 1 1 0 2 2 2 1 Glucose inhibited division protein A Trp_halogenase PF04820.9 KKK26655.1 - 0.00014 20.6 1.5 0.0051 15.4 0.0 2.2 2 0 0 2 2 2 1 Tryptophan halogenase FAD_oxidored PF12831.2 KKK26655.1 - 0.0015 17.6 0.9 0.0015 17.6 0.6 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 KKK26655.1 - 0.0037 16.3 0.0 0.0078 15.3 0.0 1.4 1 0 0 1 1 1 1 Thi4 family 3HCDH_N PF02737.13 KKK26655.1 - 0.051 13.2 0.2 0.09 12.4 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_9 PF13454.1 KKK26655.1 - 4.4 7.0 5.7 11 5.7 0.3 2.8 3 0 0 3 3 3 0 FAD-NAD(P)-binding Gly-zipper_OmpA PF13436.1 KKK26656.1 - 0.015 14.9 5.1 0.028 14.0 3.5 1.5 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain Rick_17kDa_Anti PF05433.10 KKK26656.1 - 0.037 13.6 22.7 0.066 12.8 15.7 1.4 1 0 0 1 1 1 0 Glycine zipper 2TM domain RuBisCO_large PF00016.15 KKK26656.1 - 0.042 12.7 2.3 0.056 12.2 1.6 1.1 1 0 0 1 1 1 0 Ribulose bisphosphate carboxylase large chain, catalytic domain DUF533 PF04391.7 KKK26656.1 - 0.053 12.8 4.4 0.092 12.1 3.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF533) SR-25 PF10500.4 KKK26656.1 - 0.3 10.5 13.3 0.4 10.1 9.2 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF755 PF05501.6 KKK26656.1 - 0.67 10.0 19.6 1.1 9.3 13.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF755) BLVR PF06375.6 KKK26656.1 - 0.82 9.4 10.0 1.2 8.9 6.9 1.2 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) NMD3 PF04981.8 KKK26657.1 - 5.6e-73 244.9 3.1 7.4e-73 244.5 2.1 1.2 1 0 0 1 1 1 1 NMD3 family DUF35_N PF12172.3 KKK26657.1 - 0.0043 16.9 2.6 3.5 7.6 0.1 3.4 3 0 0 3 3 3 2 Rubredoxin-like zinc ribbon domain (DUF35_N) DZR PF12773.2 KKK26657.1 - 0.28 11.0 7.6 2.7 7.8 3.2 2.8 2 1 0 2 2 2 0 Double zinc ribbon FYVE PF01363.16 KKK26657.1 - 0.34 10.8 4.4 0.97 9.3 1.0 2.5 2 0 0 2 2 2 0 FYVE zinc finger zinc-ribbons_6 PF07191.7 KKK26657.1 - 8.4 6.2 7.8 55 3.6 0.1 2.9 2 1 0 2 2 2 0 zinc-ribbons PsbH PF00737.15 KKK26658.1 - 0.12 11.9 0.1 0.12 11.9 0.1 2.5 3 0 0 3 3 3 0 Photosystem II 10 kDa phosphoprotein Fungal_trans_2 PF11951.3 KKK26659.1 - 1e-06 27.6 0.0 1.4e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK26659.1 - 0.0011 18.8 0.8 0.0011 18.8 0.5 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ABC_tran PF00005.22 KKK26660.1 - 4.1e-47 159.9 0.3 2.9e-24 85.9 0.0 4.3 3 2 0 3 3 2 2 ABC transporter AAA_21 PF13304.1 KKK26660.1 - 3.9e-17 63.1 0.1 0.0018 18.2 0.1 4.3 3 1 0 4 4 4 4 AAA domain SMC_N PF02463.14 KKK26660.1 - 1.3e-15 57.2 0.0 8.2e-06 25.2 0.0 3.6 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 KKK26660.1 - 1.2e-09 38.7 1.3 0.00041 20.7 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_29 PF13555.1 KKK26660.1 - 4.7e-09 35.6 0.1 0.0022 17.4 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 KKK26660.1 - 1.1e-07 32.6 0.1 0.0066 17.2 0.0 3.2 3 0 0 3 3 2 2 AAA domain AAA_28 PF13521.1 KKK26660.1 - 1.6e-07 31.3 0.1 0.017 15.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 KKK26660.1 - 7.5e-07 29.3 0.0 0.0063 16.6 0.0 3.2 3 0 0 3 3 2 2 AAA domain DUF258 PF03193.11 KKK26660.1 - 8.4e-07 28.3 0.0 0.00073 18.7 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 PduV-EutP PF10662.4 KKK26660.1 - 1.8e-06 27.5 0.0 0.078 12.4 0.0 2.9 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.1 KKK26660.1 - 5.1e-06 26.5 0.2 0.44 10.5 0.0 4.2 4 0 0 4 4 4 2 AAA ATPase domain AAA PF00004.24 KKK26660.1 - 9e-06 25.9 0.0 0.14 12.3 0.0 4.2 4 1 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.18 KKK26660.1 - 1.2e-05 25.1 0.0 0.019 14.9 0.0 3.1 3 0 0 3 3 2 1 50S ribosome-binding GTPase AAA_10 PF12846.2 KKK26660.1 - 1.5e-05 24.6 0.0 0.32 10.3 0.0 3.2 4 0 0 4 4 3 2 AAA-like domain HEAT_2 PF13646.1 KKK26660.1 - 1.5e-05 25.1 0.6 0.029 14.6 0.0 3.1 2 1 2 4 4 3 2 HEAT repeats AAA_18 PF13238.1 KKK26660.1 - 1.8e-05 25.0 0.2 0.2 11.9 0.0 3.4 3 0 0 3 3 2 2 AAA domain SbcCD_C PF13558.1 KKK26660.1 - 2.7e-05 23.9 0.0 0.063 13.1 0.0 2.8 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit Miro PF08477.8 KKK26660.1 - 4.1e-05 24.0 0.0 0.03 14.8 0.0 2.7 2 0 0 2 2 2 1 Miro-like protein AAA_13 PF13166.1 KKK26660.1 - 5.5e-05 21.8 0.0 0.26 9.6 0.0 3.4 3 0 0 3 3 3 2 AAA domain NACHT PF05729.7 KKK26660.1 - 6.2e-05 22.7 0.0 0.069 12.7 0.0 2.8 2 0 0 2 2 2 1 NACHT domain AAA_33 PF13671.1 KKK26660.1 - 8.4e-05 22.4 0.0 0.3 10.9 0.0 2.8 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 KKK26660.1 - 0.00011 22.3 0.0 0.58 10.3 0.0 2.6 2 0 0 2 2 2 2 RNA helicase MobB PF03205.9 KKK26660.1 - 0.00011 21.8 0.3 0.88 9.2 0.0 3.3 3 0 0 3 3 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.1 KKK26660.1 - 0.00016 21.5 0.0 0.36 10.7 0.0 3.0 3 0 0 3 3 2 1 AAA domain Arch_ATPase PF01637.13 KKK26660.1 - 0.00018 21.2 0.0 0.13 11.8 0.0 3.0 2 0 0 2 2 2 1 Archaeal ATPase AAA_15 PF13175.1 KKK26660.1 - 0.00021 20.4 2.2 0.57 9.1 0.0 3.9 3 2 2 5 5 5 1 AAA ATPase domain Dynamin_N PF00350.18 KKK26660.1 - 0.00021 21.1 0.0 0.0032 17.3 0.0 2.6 2 0 0 2 2 2 1 Dynamin family HEAT PF02985.17 KKK26660.1 - 0.00066 19.5 2.9 16 5.8 0.1 5.3 6 0 0 6 6 4 0 HEAT repeat cobW PF02492.14 KKK26660.1 - 0.00073 19.0 0.4 0.44 9.9 0.0 3.2 4 0 0 4 4 3 1 CobW/HypB/UreG, nucleotide-binding domain ArgK PF03308.11 KKK26660.1 - 0.00088 18.1 0.1 0.54 8.9 0.0 2.5 2 0 0 2 2 2 2 ArgK protein AAA_19 PF13245.1 KKK26660.1 - 0.0016 18.1 0.0 4.1 7.2 0.0 3.2 3 0 0 3 3 3 0 Part of AAA domain AAA_30 PF13604.1 KKK26660.1 - 0.0016 18.0 0.0 1.8 8.1 0.0 3.2 3 0 0 3 3 3 1 AAA domain DUF87 PF01935.12 KKK26660.1 - 0.0022 17.8 3.9 0.14 11.9 0.0 3.3 4 0 0 4 4 2 1 Domain of unknown function DUF87 AAA_25 PF13481.1 KKK26660.1 - 0.0023 17.3 0.0 2.7 7.3 0.0 2.8 2 0 0 2 2 2 1 AAA domain ATP-synt_ab PF00006.20 KKK26660.1 - 0.0042 16.5 0.0 0.78 9.1 0.0 2.5 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP_bind_1 PF03029.12 KKK26660.1 - 0.0067 15.9 0.1 3.9 6.9 0.0 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein T2SE PF00437.15 KKK26660.1 - 0.007 15.2 0.1 2.8 6.7 0.0 3.0 3 0 0 3 3 3 1 Type II/IV secretion system protein AAA_5 PF07728.9 KKK26660.1 - 0.015 15.0 0.0 12 5.6 0.0 3.5 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 KKK26660.1 - 0.017 14.3 0.1 2.7 7.1 0.0 3.1 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI Septin PF00735.13 KKK26660.1 - 0.021 13.8 0.2 1.6 7.6 0.0 2.7 3 0 0 3 3 2 0 Septin NB-ARC PF00931.17 KKK26660.1 - 0.027 13.3 0.3 0.29 9.9 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain UPF0079 PF02367.12 KKK26660.1 - 0.031 13.9 0.0 2 8.0 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 FtsK_SpoIIIE PF01580.13 KKK26660.1 - 0.038 13.4 0.2 1.2 8.5 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family MMS19_C PF12460.3 KKK26660.1 - 0.11 11.1 0.2 32 3.0 0.0 3.2 3 0 0 3 3 3 0 RNAPII transcription regulator C-terminal Med19 PF10278.4 KKK26660.1 - 0.61 9.7 7.9 84 2.7 3.7 3.8 4 0 0 4 4 4 0 Mediator of RNA pol II transcription subunit 19 HEAT_EZ PF13513.1 KKK26660.1 - 2.3 8.8 9.0 1.1e+02 3.4 0.0 5.4 4 2 2 6 6 3 0 HEAT-like repeat TPR_11 PF13414.1 KKK26661.1 - 3.6e-11 42.5 12.8 5.7e-07 29.0 0.0 6.0 5 1 1 6 6 6 2 TPR repeat TPR_17 PF13431.1 KKK26661.1 - 5.7e-05 22.9 0.0 0.015 15.4 0.0 3.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 KKK26661.1 - 7.2e-05 22.2 10.9 0.021 14.4 0.0 5.6 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.12 KKK26661.1 - 0.00036 20.2 20.5 0.0034 17.1 0.0 6.9 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_8 PF13181.1 KKK26661.1 - 0.00044 19.8 1.8 1.5 8.7 0.0 4.6 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.1 KKK26661.1 - 0.0035 17.9 0.6 0.026 15.2 0.1 5.1 5 1 2 7 7 6 2 Tetratricopeptide repeat TPR_7 PF13176.1 KKK26661.1 - 0.0038 16.9 5.7 0.55 10.1 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 KKK26661.1 - 0.0069 16.9 0.5 0.0069 16.9 0.4 6.2 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.1 KKK26661.1 - 0.02 14.8 16.1 0.28 11.1 0.0 5.4 5 2 1 6 6 6 0 Tetratricopeptide repeat Plug_translocon PF10559.4 KKK26661.1 - 0.031 13.7 0.1 0.064 12.7 0.1 1.6 1 0 0 1 1 1 0 Plug domain of Sec61p TPR_19 PF14559.1 KKK26661.1 - 3.1 8.2 14.9 0.17 12.2 1.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.1 KKK26661.1 - 3.5 7.5 11.4 0.44 10.4 0.4 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat Methyltransf_10 PF05971.7 KKK26662.1 - 1.6e-68 231.0 0.0 2.2e-68 230.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF890) MTS PF05175.9 KKK26662.1 - 0.00056 19.3 0.0 0.001 18.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 KKK26662.1 - 0.0015 18.5 0.0 0.0025 17.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KKK26662.1 - 0.1 13.1 0.0 0.19 12.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain PLDc PF00614.17 KKK26663.1 - 1.9e-13 49.7 3.7 3.7e-07 29.7 0.1 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.1 KKK26663.1 - 9.1e-13 48.0 0.0 1.9e-06 27.6 0.0 3.4 3 0 0 3 3 3 3 PLD-like domain SWIRM PF04433.12 KKK26664.1 - 7.8e-35 118.8 0.1 1.6e-34 117.8 0.1 1.6 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-bind_6 PF13921.1 KKK26664.1 - 1.7e-06 28.0 0.1 5.8e-06 26.3 0.0 2.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 KKK26664.1 - 1.7e-05 24.7 0.0 3.8e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain ZZ PF00569.12 KKK26664.1 - 0.025 14.1 4.2 0.13 11.8 2.9 2.0 1 1 0 1 1 1 0 Zinc finger, ZZ type V_ATPase_I PF01496.14 KKK26664.1 - 4.6 4.9 4.9 4.8 4.9 2.9 1.3 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family CHCH PF06747.8 KKK26665.1 - 3.7e-08 33.0 4.8 6.5e-08 32.2 3.3 1.4 1 0 0 1 1 1 1 CHCH domain GCK PF07802.6 KKK26665.1 - 0.0038 17.3 1.2 0.0077 16.3 0.8 1.5 1 0 0 1 1 1 1 GCK domain MIF4G PF02854.14 KKK26667.1 - 2.3e-59 200.3 0.1 2.6e-31 108.6 0.0 3.7 4 0 0 4 4 4 2 MIF4G domain Upf2 PF04050.9 KKK26667.1 - 3.7e-59 199.3 18.3 3.7e-59 199.3 12.7 2.1 2 0 0 2 2 2 1 Up-frameshift suppressor 2 Histone PF00125.19 KKK26668.1 - 1.6e-15 56.9 0.1 1.9e-15 56.6 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.12 KKK26668.1 - 0.0001 22.1 0.1 0.00015 21.6 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.1 KKK26668.1 - 0.00012 22.1 0.1 0.00018 21.6 0.1 1.4 1 1 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 KKK26668.1 - 0.00017 21.5 0.1 0.0003 20.7 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 KKK26668.1 - 0.018 14.7 0.0 0.021 14.5 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated CENP-T PF15511.1 KKK26668.1 - 0.022 14.0 0.0 0.022 13.9 0.0 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T XRN_N PF03159.13 KKK26669.1 - 3.4e-108 360.4 0.6 3e-106 354.1 0.0 2.2 2 0 0 2 2 2 2 XRN 5'-3' exonuclease N-terminus zf-CCHC PF00098.18 KKK26669.1 - 0.078 12.9 2.8 0.14 12.1 1.9 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.1 KKK26669.1 - 0.12 12.0 0.7 0.24 11.0 0.5 1.5 1 0 0 1 1 1 0 Zinc knuckle EPSP_synthase PF00275.15 KKK26670.1 - 6.3e-126 420.1 0.0 9.5e-126 419.5 0.0 1.2 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.15 KKK26670.1 - 2.9e-97 324.6 0.1 7.1e-97 323.4 0.0 1.6 2 0 0 2 2 2 1 3-dehydroquinate synthase DHquinase_I PF01487.10 KKK26670.1 - 8.2e-63 212.0 0.0 1.4e-62 211.3 0.0 1.4 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.17 KKK26670.1 - 1.9e-39 135.0 0.0 1.6e-38 132.0 0.0 2.2 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.6 KKK26670.1 - 3.6e-24 84.6 0.0 8.9e-24 83.3 0.0 1.7 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 KKK26670.1 - 2.8e-11 43.6 0.0 7.6e-11 42.2 0.0 1.7 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Fe-ADH_2 PF13685.1 KKK26670.1 - 3.8e-08 32.9 0.0 8.7e-08 31.7 0.0 1.6 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase AAA_17 PF13207.1 KKK26670.1 - 2e-05 25.3 0.0 0.00026 21.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KKK26670.1 - 0.017 15.4 0.0 0.041 14.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 KKK26670.1 - 0.11 12.0 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain Myotub-related PF06602.9 KKK26670.1 - 0.22 10.2 0.0 0.5 9.0 0.0 1.5 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain zf-C2H2 PF00096.21 KKK26671.1 - 5.5e-06 26.4 27.6 0.00034 20.7 0.9 5.2 5 0 0 5 5 5 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KKK26671.1 - 0.00012 22.1 27.2 0.0027 17.9 0.9 5.5 5 0 0 5 5 5 3 C2H2-type zinc finger zf-BED PF02892.10 KKK26671.1 - 0.16 11.7 1.7 0.39 10.4 1.2 1.6 1 0 0 1 1 1 0 BED zinc finger zf-Di19 PF05605.7 KKK26671.1 - 0.32 11.1 5.8 2 8.5 1.0 2.5 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Sfi1 PF08457.5 KKK26672.1 - 3.6e-208 692.6 82.2 3.6e-208 692.6 57.0 2.0 1 1 1 2 2 2 2 Sfi1 spindle body protein Cmc1 PF08583.5 KKK26673.1 - 0.0078 15.9 1.9 0.0078 15.9 1.3 1.6 1 1 1 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like NDUF_B7 PF05676.8 KKK26673.1 - 0.014 14.8 1.0 1.9 7.9 0.1 2.1 1 1 1 2 2 2 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) CHCH PF06747.8 KKK26673.1 - 0.03 14.2 1.9 0.083 12.8 1.3 1.7 1 1 0 1 1 1 0 CHCH domain tRNA-synt_1 PF00133.17 KKK26674.1 - 3.2e-223 742.1 0.0 5.1e-223 741.4 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 KKK26674.1 - 1.4e-27 96.3 0.1 4.2e-27 94.7 0.0 1.8 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 KKK26674.1 - 1.2e-17 63.6 0.0 9.1e-08 31.1 0.0 4.1 3 1 0 3 3 3 3 tRNA synthetases class I (M) Uso1_p115_head PF04869.9 KKK26675.1 - 9.5e-112 372.7 0.0 1.9e-111 371.7 0.0 1.6 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, head region Uso1_p115_C PF04871.8 KKK26675.1 - 1.5e-08 34.6 30.5 1.5e-08 34.6 21.2 3.8 2 1 1 3 3 3 1 Uso1 / p115 like vesicle tethering protein, C terminal region Filament PF00038.16 KKK26675.1 - 7.9e-06 25.5 52.9 0.00059 19.3 11.6 2.3 1 1 1 2 2 2 2 Intermediate filament protein IncA PF04156.9 KKK26675.1 - 0.0013 18.4 22.1 0.0013 18.4 15.3 4.5 1 1 3 4 4 4 1 IncA protein Arm PF00514.18 KKK26675.1 - 0.016 15.0 1.2 3.4 7.6 0.0 4.1 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat DUF3584 PF12128.3 KKK26675.1 - 0.32 8.2 58.7 0.7 7.1 19.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) Reo_sigmaC PF04582.7 KKK26675.1 - 2 7.4 17.4 0.57 9.3 4.8 3.4 1 1 2 3 3 3 0 Reovirus sigma C capsid protein Baculo_PEP_C PF04513.7 KKK26675.1 - 4.5 7.0 17.2 4.9 6.9 2.8 4.5 2 1 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Histone PF00125.19 KKK26676.1 - 1.1e-31 108.7 0.4 1.8e-31 108.0 0.3 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 KKK26676.1 - 2.9e-06 27.3 0.0 4.4e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 KKK26676.1 - 0.0035 17.3 0.3 0.0073 16.3 0.0 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 KKK26676.1 - 0.04 13.6 0.1 0.069 12.8 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated MFS_1 PF07690.11 KKK26677.1 - 9.4e-41 139.6 53.8 9.4e-41 139.6 37.3 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KKK26677.1 - 8.7e-05 21.2 16.3 8.7e-05 21.2 11.3 4.0 2 2 3 5 5 5 2 Sugar (and other) transporter Keratin_assoc PF09775.4 KKK26677.1 - 0.004 16.6 3.1 0.004 16.6 2.2 2.6 2 0 0 2 2 2 1 Keratinocyte-associated protein 2 Rav1p_C PF12234.3 KKK26678.1 - 4.9e-276 916.9 0.0 6.1e-276 916.6 0.0 1.1 1 0 0 1 1 1 1 RAVE protein 1 C terminal WD40 PF00400.27 KKK26678.1 - 3.4e-05 23.5 0.5 1.1 9.2 0.0 4.1 3 0 0 3 3 3 2 WD domain, G-beta repeat KAT11 PF08214.6 KKK26680.1 - 2.8e-104 348.9 0.0 4.5e-104 348.2 0.0 1.3 1 0 0 1 1 1 1 Histone acetylation protein Glyco_transf_21 PF13506.1 KKK26681.1 - 1.6e-12 47.0 0.1 1.4e-05 24.4 0.0 3.8 2 1 0 2 2 2 2 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.1 KKK26681.1 - 4.6e-11 42.9 0.0 1.3e-10 41.4 0.0 1.8 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 KKK26681.1 - 0.00028 20.6 0.0 0.0074 15.9 0.0 2.3 1 1 0 1 1 1 1 Glycosyl transferase family 2 Ank_2 PF12796.2 KKK26682.1 - 1.1e-15 57.6 1.2 1.8e-15 57.0 0.5 1.5 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 KKK26682.1 - 1.4e-13 49.9 0.7 2e-10 39.9 0.1 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 KKK26682.1 - 6.3e-13 48.8 1.2 3.5e-07 30.5 0.2 2.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 KKK26682.1 - 9e-12 44.8 2.4 6.7e-08 32.5 0.3 3.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KKK26682.1 - 8.4e-11 41.0 0.7 3.6e-07 29.7 0.1 3.1 3 0 0 3 3 3 2 Ankyrin repeat WW PF00397.21 KKK26683.1 - 3.2e-07 30.0 2.6 3.2e-07 30.0 1.8 2.6 3 0 0 3 3 3 1 WW domain AIPR PF10592.4 KKK26683.1 - 0.047 13.0 2.0 0.067 12.5 1.4 1.2 1 0 0 1 1 1 0 AIPR protein Spore_coat_CotO PF14153.1 KKK26683.1 - 2.5 7.5 13.3 0.38 10.1 2.8 2.1 2 0 0 2 2 2 0 Spore coat protein CotO Hydrophobin PF01185.13 KKK26684.1 - 2.8e-15 56.4 7.6 3.8e-15 56.1 5.2 1.2 1 0 0 1 1 1 1 Fungal hydrophobin NMO PF03060.10 KKK26685.1 - 4.2e-64 216.7 0.6 6.3e-64 216.1 0.4 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 KKK26685.1 - 4.4e-11 42.2 0.0 0.00016 20.6 0.0 2.2 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 KKK26685.1 - 0.0068 15.2 0.5 0.013 14.3 0.3 1.5 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.12 KKK26685.1 - 0.047 12.6 0.5 0.12 11.2 0.4 1.7 1 1 0 1 1 1 0 Conserved region in glutamate synthase tRNA-synt_1e PF01406.14 KKK26686.1 - 3e-115 384.4 0.0 4.9e-115 383.7 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.6 KKK26686.1 - 2.3e-06 26.5 1.1 0.024 13.2 0.1 2.8 3 0 0 3 3 3 2 tRNA synthetases class I (M) GCD14 PF08704.5 KKK26687.1 - 2.8e-59 200.6 1.0 1.4e-33 116.4 0.1 3.2 2 1 0 2 2 2 2 tRNA methyltransferase complex GCD14 subunit Methyltransf_26 PF13659.1 KKK26687.1 - 0.00091 19.2 0.0 0.0018 18.2 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KKK26687.1 - 0.092 13.3 0.1 0.62 10.6 0.1 2.1 1 1 0 1 1 1 0 Methyltransferase domain TPR_11 PF13414.1 KKK26688.1 - 2e-05 24.1 0.1 5.7e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 TPR repeat UBA PF00627.26 KKK26688.1 - 0.00056 19.6 0.1 0.0019 17.9 0.0 1.9 1 0 0 1 1 1 1 UBA/TS-N domain DnaJ PF00226.26 KKK26688.1 - 0.0098 15.6 0.0 0.028 14.1 0.0 1.8 1 0 0 1 1 1 1 DnaJ domain TPR_16 PF13432.1 KKK26688.1 - 0.024 15.2 2.1 0.024 15.2 1.4 3.5 2 1 2 4 4 4 0 Tetratricopeptide repeat TetR_C PF02909.12 KKK26688.1 - 0.027 14.1 0.0 0.095 12.3 0.0 1.9 1 0 0 1 1 1 0 Tetracyclin repressor, C-terminal all-alpha domain TPR_2 PF07719.12 KKK26688.1 - 0.093 12.7 5.3 0.031 14.1 0.8 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat adh_short_C2 PF13561.1 KKK26690.1 - 8.8e-25 87.8 0.0 1.1e-24 87.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KKK26690.1 - 8e-20 71.4 0.2 1.7e-19 70.3 0.1 1.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KKK26690.1 - 2.8e-08 33.6 0.2 4.7e-07 29.6 0.0 2.0 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 KKK26690.1 - 0.0094 15.4 0.1 0.017 14.6 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.14 KKK26690.1 - 0.0098 15.0 0.0 0.017 14.2 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.12 KKK26690.1 - 0.05 14.0 0.3 0.096 13.1 0.2 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.11 KKK26690.1 - 0.057 12.8 0.1 0.085 12.2 0.1 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA RmlD_sub_bind PF04321.12 KKK26690.1 - 0.061 12.2 0.1 6.2 5.6 0.0 2.2 2 0 0 2 2 2 0 RmlD substrate binding domain NAD_binding_10 PF13460.1 KKK26690.1 - 0.11 12.4 0.2 0.23 11.4 0.1 1.4 1 0 0 1 1 1 0 NADH(P)-binding eIF-6 PF01912.13 KKK26691.1 - 1.4e-47 161.3 0.1 1.5e-47 161.2 0.0 1.0 1 0 0 1 1 1 1 eIF-6 family Voldacs PF03517.8 KKK26694.1 - 7.3e-28 97.0 0.2 7.3e-28 97.0 0.2 2.1 3 0 0 3 3 3 1 Regulator of volume decrease after cellular swelling DUF605 PF04652.11 KKK26694.1 - 1.2 8.4 10.3 1.8 7.9 7.2 1.2 1 0 0 1 1 1 0 Vta1 like Abhydrolase_2 PF02230.11 KKK26695.1 - 9.2e-08 31.7 0.0 2.2e-07 30.5 0.0 1.6 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 KKK26695.1 - 2.4e-07 30.8 3.6 5.6e-07 29.6 2.5 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KKK26695.1 - 9.3e-06 25.4 0.0 1.4e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KKK26695.1 - 0.035 13.9 0.0 0.075 12.8 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase Metallophos PF00149.23 KKK26696.1 - 7.4e-41 139.7 0.6 1.1e-40 139.1 0.4 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase MFS_1 PF07690.11 KKK26697.1 - 4.3e-25 88.1 18.6 9.5e-25 87.0 12.9 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Ion_trans_2 PF07885.11 KKK26698.1 - 1.6e-25 88.6 30.3 2.8e-15 55.7 5.5 3.6 3 1 1 4 4 4 2 Ion channel Ion_trans PF00520.26 KKK26698.1 - 0.0075 15.5 0.9 0.0075 15.5 0.7 4.2 3 3 1 4 4 4 2 Ion transport protein Claudin_2 PF13903.1 KKK26698.1 - 0.14 11.7 13.4 0.15 11.7 5.8 3.1 3 1 0 3 3 3 0 PMP-22/EMP/MP20/Claudin tight junction DUF1345 PF07077.6 KKK26698.1 - 0.17 11.3 5.8 3.5 7.1 0.0 3.5 2 2 2 4 4 4 0 Protein of unknown function (DUF1345) Ribosomal_L19 PF01245.15 KKK26700.1 - 1.7e-19 69.6 0.3 3.1e-19 68.8 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L19 DUF3850 PF12961.2 KKK26700.1 - 0.058 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3850) RdRP PF05183.7 KKK26701.1 - 4.8e-126 421.7 0.0 6.7e-126 421.2 0.0 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase Opi1 PF08618.5 KKK26702.1 - 3.6e-100 335.8 11.5 2.3e-60 204.7 0.1 4.1 1 1 3 4 4 4 3 Transcription factor Opi1 Perilipin PF03036.11 KKK26702.1 - 0.00032 19.6 1.4 0.028 13.2 0.1 2.3 2 0 0 2 2 2 2 Perilipin family NmrA PF05368.8 KKK26703.1 - 1.1e-30 106.5 0.0 1.3e-30 106.3 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KKK26703.1 - 1.8e-12 47.6 0.0 2.7e-12 47.0 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 KKK26703.1 - 3.1e-06 26.4 0.0 4.1e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Semialdhyde_dh PF01118.19 KKK26703.1 - 3.1e-06 27.4 0.0 7e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 KKK26703.1 - 0.0036 17.3 0.0 0.009 16.1 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase DapB_N PF01113.15 KKK26703.1 - 0.054 13.4 0.0 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus AA_permease PF00324.16 KKK26704.1 - 2.9e-74 250.1 30.8 3.2e-74 249.9 21.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KKK26704.1 - 2.4e-22 79.0 31.3 3e-22 78.7 21.7 1.1 1 0 0 1 1 1 1 Amino acid permease Hid1 PF12722.2 KKK26705.1 - 1.3e-280 933.1 0.0 1.9e-280 932.5 0.0 1.3 1 1 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.4 KKK26705.1 - 2.4e-84 283.7 0.0 3.7e-84 283.1 0.0 1.2 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein NPCC PF08058.6 KKK26705.1 - 1.3e-32 112.6 0.1 3.8e-31 107.8 0.1 2.7 1 1 0 1 1 1 1 Nuclear pore complex component DASH_Spc19 PF08287.6 KKK26705.1 - 0.052 13.1 0.3 0.12 11.9 0.1 1.7 2 0 0 2 2 2 0 Spc19 AMP-binding PF00501.23 KKK26706.1 - 7.1e-07 27.9 0.3 7.2e-06 24.6 0.2 2.0 1 1 0 1 1 1 1 AMP-binding enzyme DUF4231 PF14015.1 KKK26706.1 - 0.17 11.8 0.5 0.97 9.4 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) Ribosomal_S3Ae PF01015.13 KKK26707.1 - 8.5e-80 266.6 5.8 1e-79 266.3 4.0 1.1 1 0 0 1 1 1 1 Ribosomal S3Ae family Syntaxin PF00804.20 KKK26707.1 - 0.1 12.8 0.6 0.37 10.9 0.0 2.2 2 1 0 2 2 2 0 Syntaxin UPRTase PF14681.1 KKK26708.1 - 9.8e-68 227.4 0.0 1.1e-67 227.2 0.0 1.1 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 KKK26708.1 - 0.0001 21.9 0.0 0.00017 21.2 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Flu_C_NS1 PF03506.8 KKK26708.1 - 0.095 12.4 0.5 0.16 11.6 0.3 1.3 1 0 0 1 1 1 0 Influenza C non-structural protein (NS1) DKCLD PF08068.7 KKK26709.1 - 1.9e-29 101.3 0.1 1.1e-28 98.8 0.0 2.3 2 0 0 2 2 2 1 DKCLD (NUC011) domain DER1 PF04511.10 KKK26709.1 - 1.7e-25 89.7 2.7 2.3e-25 89.2 1.9 1.2 1 0 0 1 1 1 1 Der1-like family TruB_N PF01509.13 KKK26709.1 - 8.2e-24 84.4 0.2 2.1e-21 76.6 0.1 3.2 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.15 KKK26709.1 - 6.9e-21 73.7 1.1 1.4e-20 72.7 0.8 1.6 1 0 0 1 1 1 1 PUA domain Rhomboid PF01694.17 KKK26709.1 - 0.12 12.3 4.8 0.39 10.7 3.4 1.9 1 1 0 1 1 1 0 Rhomboid family Med19 PF10278.4 KKK26709.1 - 2.5 7.7 17.5 4.6 6.8 12.1 1.4 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 CLTH PF10607.4 KKK26710.1 - 2.1e-35 121.5 0.0 4.6e-35 120.4 0.0 1.6 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain Phage_GP20 PF06810.6 KKK26710.1 - 0.39 10.1 4.0 0.28 10.6 0.9 2.0 2 0 0 2 2 2 0 Phage minor structural protein GP20 Tom37_C PF11801.3 KKK26710.1 - 3.1 7.6 6.8 0.92 9.3 1.3 2.1 1 1 1 2 2 2 0 Tom37 C-terminal domain DUF2431 PF10354.4 KKK26711.1 - 1.6e-45 155.0 0.0 6.1e-29 101.1 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF2431) Nucleoplasmin PF03066.10 KKK26711.1 - 0.26 10.8 21.4 0.74 9.3 2.6 2.4 2 0 0 2 2 2 0 Nucleoplasmin TRAP_alpha PF03896.11 KKK26711.1 - 0.34 9.8 10.4 1.6 7.7 0.8 2.2 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit TLP-20 PF06088.6 KKK26711.1 - 0.95 9.1 14.0 0.71 9.5 0.2 3.0 3 0 0 3 3 3 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Pex14_N PF04695.8 KKK26711.1 - 1.3 9.0 6.4 0.71 9.9 1.5 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region RXT2_N PF08595.6 KKK26711.1 - 1.4 8.7 12.5 0.61 9.8 1.2 2.5 2 0 0 2 2 2 0 RXT2-like, N-terminal TraV PF09676.5 KKK26711.1 - 2.2 9.0 8.4 2.1 9.0 0.3 2.7 2 0 0 2 2 2 0 Type IV conjugative transfer system lipoprotein (TraV) dsrm PF00035.20 KKK26711.1 - 4.2 8.0 0.0 4.2 8.0 0.0 3.7 3 1 0 3 3 3 0 Double-stranded RNA binding motif Trypan_PARP PF05887.6 KKK26711.1 - 6.5 6.5 12.8 14 5.4 0.5 2.5 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) GOLD_2 PF13897.1 KKK26711.1 - 8.8 6.5 13.7 14 5.9 0.1 3.2 3 0 0 3 3 3 0 Golgi-dynamics membrane-trafficking Sigma70_ner PF04546.8 KKK26711.1 - 9 5.8 20.3 1.2 8.7 2.5 2.7 3 0 0 3 3 3 0 Sigma-70, non-essential region HGTP_anticodon2 PF12745.2 KKK26711.1 - 9.3 5.3 9.6 1.8 7.6 0.8 2.6 3 0 0 3 3 3 0 Anticodon binding domain of tRNAs UAA PF08449.6 KKK26712.1 - 6.1e-11 41.7 16.6 7.7e-11 41.4 11.5 1.1 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 KKK26712.1 - 8.8e-10 38.4 5.4 8.8e-10 38.4 3.8 2.6 2 2 0 2 2 2 1 Triose-phosphate Transporter family Herpes_LMP1 PF05297.6 KKK26712.1 - 0.00092 18.2 2.7 0.0013 17.7 1.8 1.1 1 0 0 1 1 1 1 Herpesvirus latent membrane protein 1 (LMP1) PHO4 PF01384.15 KKK26712.1 - 0.0049 15.5 3.1 0.0049 15.5 2.2 2.4 2 1 1 3 3 3 1 Phosphate transporter family EamA PF00892.15 KKK26712.1 - 0.01 15.8 5.0 0.01 15.8 3.5 2.3 2 0 0 2 2 2 0 EamA-like transporter family Thioredoxin PF00085.15 KKK26713.1 - 2.3e-05 23.9 0.0 3.7e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Glypican PF01153.14 KKK26713.1 - 0.31 9.6 3.3 0.42 9.1 2.3 1.2 1 0 0 1 1 1 0 Glypican PGA2 PF07543.7 KKK26713.1 - 1.3 8.8 4.9 2.2 8.0 3.4 1.3 1 0 0 1 1 1 0 Protein trafficking PGA2 SMI1_KNR4 PF09346.5 KKK26714.1 - 7.4e-36 123.0 0.0 1.2e-35 122.3 0.0 1.4 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) PNRC PF15365.1 KKK26715.1 - 4.7e-07 29.7 4.9 4.7e-07 29.7 3.4 2.2 2 1 0 2 2 2 1 Proline-rich nuclear receptor coactivator Pex16 PF08610.5 KKK26715.1 - 2.9 6.7 7.0 3.5 6.5 4.9 1.1 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) zf-rbx1 PF12678.2 KKK26716.1 - 7.7e-36 122.0 13.5 9.5e-36 121.7 9.3 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 KKK26716.1 - 1.5e-17 63.1 10.5 2e-17 62.8 7.3 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 KKK26716.1 - 3.5e-07 29.9 12.8 2.2e-06 27.3 8.9 2.0 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 KKK26716.1 - 0.0012 18.5 11.9 0.021 14.4 8.3 2.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KKK26716.1 - 0.0034 17.0 9.7 0.31 10.7 6.9 2.2 1 1 1 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KKK26716.1 - 0.037 14.0 12.9 1 9.4 9.0 2.3 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 KKK26716.1 - 0.17 11.9 9.3 0.75 9.8 6.5 1.9 1 1 1 2 2 2 0 FANCL C-terminal domain zf-RING_UBOX PF13445.1 KKK26716.1 - 0.44 10.3 6.5 11 5.8 4.5 2.2 1 1 0 1 1 1 0 RING-type zinc-finger zf-HC5HC2H_2 PF13832.1 KKK26716.1 - 0.74 9.8 9.7 1.6 8.7 6.7 1.7 1 1 0 1 1 1 0 PHD-zinc-finger like domain zf-RING_5 PF14634.1 KKK26716.1 - 0.86 9.3 11.8 6.3 6.6 8.2 2.3 1 1 0 1 1 1 0 zinc-RING finger domain zf-HC5HC2H PF13771.1 KKK26716.1 - 0.96 9.6 10.5 46 4.2 7.3 2.2 1 1 0 1 1 1 0 PHD-like zinc-binding domain GHMP_kinases_N PF00288.21 KKK26717.1 - 1.4e-13 50.6 0.0 3e-13 49.6 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 KKK26717.1 - 0.00014 22.0 0.0 0.00027 21.0 0.0 1.4 1 0 0 1 1 1 1 GHMP kinases C terminal CorA PF01544.13 KKK26718.1 - 3e-42 144.6 0.0 5.3e-42 143.8 0.0 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein 2-Hacid_dh_C PF02826.14 KKK26719.1 - 1.1e-51 174.4 0.0 1.8e-51 173.8 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KKK26719.1 - 1.6e-37 127.9 0.0 2.2e-37 127.4 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 KKK26719.1 - 7.6e-06 25.8 0.1 2.4e-05 24.2 0.1 1.8 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase ACT PF01842.20 KKK26719.1 - 0.00063 19.1 0.0 0.0023 17.3 0.0 2.0 1 0 0 1 1 1 1 ACT domain AdoHcyase_NAD PF00670.16 KKK26719.1 - 0.00084 19.2 0.0 0.0023 17.7 0.0 1.7 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain IlvN PF07991.7 KKK26719.1 - 0.022 14.1 0.1 0.54 9.6 0.0 2.3 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain 3HCDH_N PF02737.13 KKK26719.1 - 0.034 13.7 0.4 0.96 9.0 0.2 2.7 2 1 1 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain XdhC_C PF13478.1 KKK26719.1 - 0.11 12.8 0.0 0.27 11.5 0.0 1.7 1 0 0 1 1 1 0 XdhC Rossmann domain tRNA-synt_2b PF00587.20 KKK26720.1 - 5.2e-33 114.0 0.0 7.6e-33 113.5 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 KKK26720.1 - 1.3e-16 60.5 5.2 1.3e-16 60.5 3.6 1.9 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain Mnd1 PF03962.10 KKK26720.1 - 0.15 11.7 5.1 0.038 13.6 0.7 1.9 2 0 0 2 2 2 0 Mnd1 family DUF4375 PF14300.1 KKK26720.1 - 0.23 11.4 2.5 0.21 11.6 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4375) NADH_B2 PF14813.1 KKK26721.1 - 0.047 13.3 0.1 0.049 13.3 0.1 1.1 1 0 0 1 1 1 0 NADH dehydrogenase 1 beta subcomplex subunit 2 Pkinase PF00069.20 KKK26722.1 - 5.1e-62 209.3 0.0 6.1e-62 209.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK26722.1 - 1e-24 87.0 0.0 1.3e-24 86.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase P5-ATPase PF12409.3 KKK26723.1 - 1.3e-38 131.5 1.1 2.2e-38 130.7 0.1 2.0 2 0 0 2 2 2 1 P5-type ATPase cation transporter E1-E2_ATPase PF00122.15 KKK26723.1 - 5.9e-31 107.2 0.7 1.1e-30 106.3 0.0 1.8 2 0 0 2 2 2 1 E1-E2 ATPase HAD PF12710.2 KKK26723.1 - 2.5e-27 96.2 0.0 1.9e-26 93.4 0.0 2.4 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KKK26723.1 - 3.1e-15 57.1 0.0 2e-14 54.5 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KKK26723.1 - 0.00052 19.4 0.3 0.0022 17.4 0.0 2.1 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 KKK26723.1 - 0.15 11.6 0.2 1.6 8.2 0.0 2.4 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase VirK PF06903.7 KKK26723.1 - 0.16 11.7 0.0 0.4 10.4 0.0 1.6 1 0 0 1 1 1 0 VirK protein AAA_18 PF13238.1 KKK26724.1 - 1.3e-24 86.9 0.3 2e-24 86.3 0.0 1.4 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KKK26724.1 - 1.3e-14 55.0 0.4 2.7e-14 54.0 0.3 1.6 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 KKK26724.1 - 0.00011 22.4 0.0 0.00018 21.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 KKK26724.1 - 0.00056 19.7 0.0 0.00099 19.0 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 KKK26724.1 - 0.0016 18.4 0.0 0.0027 17.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain ADK PF00406.17 KKK26724.1 - 0.0029 17.4 0.0 0.0062 16.4 0.0 1.6 2 0 0 2 2 2 1 Adenylate kinase AAA_14 PF13173.1 KKK26724.1 - 0.0061 16.4 0.0 0.013 15.3 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 KKK26724.1 - 0.0066 16.5 0.1 0.0082 16.2 0.1 1.6 1 1 0 1 1 1 1 AAA domain Cytidylate_kin2 PF13189.1 KKK26724.1 - 0.0076 16.1 0.0 0.0088 15.9 0.0 1.4 1 1 0 1 1 1 1 Cytidylate kinase-like family AAA_16 PF13191.1 KKK26724.1 - 0.0084 16.1 0.0 0.016 15.2 0.0 1.5 2 0 0 2 2 2 1 AAA ATPase domain KTI12 PF08433.5 KKK26724.1 - 0.014 14.6 0.0 0.021 14.0 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Stn1_C PF12659.2 KKK26724.1 - 0.019 14.7 0.0 6 6.7 0.0 2.1 1 1 1 2 2 2 0 Telomere capping C-terminal wHTH Viral_helicase1 PF01443.13 KKK26724.1 - 0.031 13.8 0.0 0.042 13.3 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.4 KKK26724.1 - 0.036 13.0 0.0 0.036 13.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NTPase_1 PF03266.10 KKK26724.1 - 0.036 13.7 0.0 0.062 13.0 0.0 1.4 1 0 0 1 1 1 0 NTPase RNA_helicase PF00910.17 KKK26724.1 - 0.061 13.5 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_10 PF12846.2 KKK26724.1 - 0.065 12.6 0.0 0.1 12.0 0.0 1.5 2 0 0 2 2 2 0 AAA-like domain IstB_IS21 PF01695.12 KKK26724.1 - 0.1 12.0 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein Ham1p_like PF01725.11 KKK26725.1 - 7.6e-54 181.9 0.0 8.6e-54 181.7 0.0 1.0 1 0 0 1 1 1 1 Ham1 family Ras PF00071.17 KKK26726.1 - 1.5e-38 131.7 0.6 1.9e-37 128.1 0.4 1.9 1 1 0 1 1 1 1 Ras family Miro PF08477.8 KKK26726.1 - 2.7e-11 43.9 0.4 1.5e-10 41.6 0.2 1.9 1 1 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 KKK26726.1 - 3.6e-06 26.9 0.0 4e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.16 KKK26726.1 - 2.6e-05 23.5 0.0 0.0014 17.8 0.0 2.0 1 1 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 KKK26726.1 - 0.0017 17.5 0.0 0.0058 15.8 0.0 1.7 1 1 1 2 2 2 1 Signal recognition particle receptor beta subunit AAA_14 PF13173.1 KKK26726.1 - 0.0087 15.9 0.0 0.011 15.6 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 KKK26726.1 - 0.0091 15.9 0.0 0.017 15.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain FeoB_N PF02421.13 KKK26726.1 - 0.06 12.6 0.0 1.4 8.1 0.0 2.0 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_18 PF13238.1 KKK26726.1 - 0.1 12.9 0.0 0.13 12.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain WAPL PF07814.8 KKK26727.1 - 8.1e-49 166.2 0.0 3.7e-48 164.0 0.0 1.9 2 0 0 2 2 2 1 Wings apart-like protein regulation of heterochromatin Myosin_head PF00063.16 KKK26728.1 - 4.9e-247 821.4 2.7 4.9e-247 821.4 1.8 1.6 2 0 0 2 2 2 1 Myosin head (motor domain) NAP PF00956.13 KKK26728.1 - 2.7e-85 285.3 9.3 2.7e-85 285.3 6.4 3.3 3 1 0 3 3 1 1 Nucleosome assembly protein (NAP) DIL PF01843.14 KKK26728.1 - 1.3e-34 118.1 3.4 3.9e-34 116.6 2.3 1.9 1 0 0 1 1 1 1 DIL domain IQ PF00612.22 KKK26728.1 - 9.9e-14 49.6 33.7 6.9e-05 22.1 0.1 6.8 6 0 0 6 6 6 5 IQ calmodulin-binding motif AAA_22 PF13401.1 KKK26728.1 - 0.00015 21.8 1.6 0.0031 17.6 0.0 3.0 2 0 0 2 2 2 1 AAA domain CENP-B_dimeris PF09026.5 KKK26728.1 - 0.00023 21.3 20.7 0.0023 18.1 4.7 2.8 2 0 0 2 2 2 2 Centromere protein B dimerisation domain AAA_16 PF13191.1 KKK26728.1 - 0.026 14.5 1.3 0.16 11.9 0.0 2.6 2 0 0 2 2 2 0 AAA ATPase domain TMP_2 PF06791.8 KKK26728.1 - 0.032 13.8 1.9 0.098 12.2 1.3 1.9 1 0 0 1 1 1 0 Prophage tail length tape measure protein AAA_19 PF13245.1 KKK26728.1 - 0.034 13.8 0.0 0.1 12.3 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain DUF258 PF03193.11 KKK26728.1 - 0.039 13.1 0.0 0.11 11.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function, DUF258 GAS PF13851.1 KKK26728.1 - 0.059 12.5 36.5 0.01 15.0 9.1 3.3 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding zf-C4H2 PF10146.4 KKK26728.1 - 0.094 12.7 9.5 0.7 9.8 5.8 2.8 2 0 0 2 2 2 0 Zinc finger-containing protein IncA PF04156.9 KKK26728.1 - 0.25 10.8 40.3 0.46 10.0 11.7 3.2 2 1 0 3 3 2 0 IncA protein DUF3450 PF11932.3 KKK26728.1 - 0.6 9.3 29.0 0.17 11.0 10.0 2.6 1 1 0 2 2 2 0 Protein of unknown function (DUF3450) Reo_sigmaC PF04582.7 KKK26728.1 - 1.6 7.8 5.5 3.2 6.8 3.2 1.8 1 1 0 1 1 1 0 Reovirus sigma C capsid protein FlaC_arch PF05377.6 KKK26728.1 - 1.7 8.6 11.8 0.18 11.7 0.5 4.1 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) FUSC PF04632.7 KKK26728.1 - 3.2 6.0 6.9 5.4 5.3 4.8 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family PBD PF00786.23 KKK26729.1 - 0.014 15.7 0.1 0.072 13.5 0.1 2.3 1 0 0 1 1 1 0 P21-Rho-binding domain Es2 PF09751.4 KKK26730.1 - 2.3e-115 386.3 0.1 2.3e-115 386.3 0.1 1.4 2 0 0 2 2 2 1 Nuclear protein Es2 Mid1 PF12929.2 KKK26731.1 - 1.9e-106 356.3 25.5 2.7e-64 217.4 11.5 3.0 1 1 1 2 2 2 2 Stretch-activated Ca2+-permeable channel component AA_kinase PF00696.23 KKK26732.1 - 3.1e-42 144.7 0.3 4.8e-42 144.1 0.2 1.3 1 0 0 1 1 1 1 Amino acid kinase family ACT_7 PF13840.1 KKK26732.1 - 1.9e-12 46.5 0.8 2.1e-10 39.9 0.1 2.7 2 0 0 2 2 2 2 ACT domain ACT PF01842.20 KKK26732.1 - 5.3e-12 44.9 0.4 1e-09 37.6 0.1 3.0 2 1 0 2 2 2 2 ACT domain Peptidase_C78 PF07910.8 KKK26733.1 - 3.9e-70 235.3 0.0 4.7e-70 235.1 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C78 Hist_deacetyl PF00850.14 KKK26733.1 - 0.00092 18.5 0.0 0.0012 18.2 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain SseB_C PF14581.1 KKK26733.1 - 0.011 15.6 0.0 0.026 14.3 0.0 1.7 1 0 0 1 1 1 0 SseB protein C-terminal domain Ribosomal_L23eN PF03939.8 KKK26734.1 - 1.1e-23 83.0 7.6 1.1e-23 83.0 5.3 1.8 2 0 0 2 2 2 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.15 KKK26734.1 - 3.1e-17 62.3 2.8 7.4e-17 61.0 1.9 1.7 1 1 0 1 1 1 1 Ribosomal protein L23 zf-Tim10_DDP PF02953.10 KKK26735.1 - 4e-22 77.2 2.2 5.3e-22 76.8 1.5 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Sox_C_TAD PF12067.3 KKK26735.1 - 0.15 12.1 0.1 0.17 12.0 0.1 1.1 1 0 0 1 1 1 0 Sox C-terminal transactivation domain G10 PF01125.12 KKK26736.1 - 2.6e-41 140.5 0.3 3e-41 140.3 0.2 1.0 1 0 0 1 1 1 1 G10 protein Fork_head PF00250.13 KKK26737.1 - 1.6e-36 124.2 0.1 2.8e-36 123.4 0.1 1.4 1 0 0 1 1 1 1 Fork head domain PDT PF00800.13 KKK26738.1 - 4.7e-67 225.0 0.1 4.7e-67 225.0 0.1 1.5 2 0 0 2 2 2 1 Prephenate dehydratase eRF1_2 PF03464.10 KKK26739.1 - 5.1e-47 159.5 0.1 8.2e-47 158.8 0.1 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 KKK26739.1 - 1.5e-39 134.7 0.5 3e-39 133.7 0.4 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.10 KKK26739.1 - 2.4e-28 98.3 0.0 4.2e-28 97.5 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 Ribosomal_L7Ae PF01248.21 KKK26739.1 - 0.078 12.4 0.0 0.18 11.2 0.0 1.6 1 0 0 1 1 1 0 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family HMG_CoA_synt_N PF01154.12 KKK26739.1 - 0.17 11.4 1.1 0.35 10.4 0.6 1.7 1 1 0 1 1 1 0 Hydroxymethylglutaryl-coenzyme A synthase N terminal Aa_trans PF01490.13 KKK26740.1 - 2.4e-70 237.1 19.0 2.8e-70 236.8 13.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 KKK26740.1 - 2.5e-05 23.3 4.3 2.5e-05 23.3 3.0 2.1 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family DUF3321 PF11968.3 KKK26741.1 - 7.4e-58 195.7 0.0 1e-57 195.3 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase (DUF3321) Methyltransf_23 PF13489.1 KKK26741.1 - 0.00018 21.2 0.0 0.00026 20.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Serine_rich PF08824.5 KKK26741.1 - 0.11 12.1 0.1 0.19 11.4 0.1 1.4 1 0 0 1 1 1 0 Serine rich protein interaction domain TPR_11 PF13414.1 KKK26742.1 - 0.0016 18.0 0.2 0.012 15.2 0.0 2.4 2 1 1 3 3 3 1 TPR repeat TPR_17 PF13431.1 KKK26742.1 - 0.1 12.8 0.1 1 9.7 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Glyoxalase PF00903.20 KKK26743.1 - 8.2e-21 74.3 0.3 1.4e-15 57.3 0.0 2.4 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 KKK26743.1 - 5.2e-14 52.1 0.1 8.7e-06 25.7 0.0 2.5 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 KKK26743.1 - 1.8e-08 34.9 0.0 0.00086 19.8 0.0 2.5 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_3 PF13468.1 KKK26743.1 - 6.7e-06 26.1 0.1 0.12 12.2 0.1 3.5 3 1 0 3 3 3 2 Glyoxalase-like domain Glyoxalase_5 PF14696.1 KKK26743.1 - 6.7e-05 22.8 0.0 0.0021 18.0 0.0 2.4 1 1 0 1 1 1 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal FAA_hydrolase PF01557.13 KKK26744.1 - 7.6e-46 156.3 0.0 1e-45 155.9 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.6 KKK26744.1 - 1.9e-24 85.7 0.0 3.8e-24 84.7 0.0 1.5 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal HgmA PF04209.8 KKK26745.1 - 1.4e-192 639.7 0.0 1.6e-192 639.5 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase p450 PF00067.17 KKK26746.1 - 3.5e-72 243.3 0.0 4e-72 243.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 zf-DNA_Pol PF08996.5 KKK26748.1 - 0.0026 17.1 3.5 0.57 9.5 0.3 2.2 2 0 0 2 2 2 2 DNA Polymerase alpha zinc finger DZR PF12773.2 KKK26748.1 - 0.063 13.0 4.8 1.5 8.6 0.2 2.5 2 0 0 2 2 2 0 Double zinc ribbon IKI3 PF04762.7 KKK26749.1 - 0 1125.5 0.0 0 1125.3 0.0 1.0 1 0 0 1 1 1 1 IKI3 family COX7C PF02935.11 KKK26749.1 - 3.4e-10 39.5 2.1 7.9e-10 38.3 1.5 1.6 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc BTAD PF03704.12 KKK26749.1 - 0.045 14.0 1.7 0.089 13.0 1.2 1.4 1 0 0 1 1 1 0 Bacterial transcriptional activator domain rRNA_proc-arch PF13234.1 KKK26750.1 - 2.3e-103 345.0 0.0 4.8e-103 343.9 0.0 1.6 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.7 KKK26750.1 - 1.2e-64 216.9 3.3 1.2e-64 216.9 2.3 1.9 2 0 0 2 2 2 1 DSHCT (NUC185) domain DEAD PF00270.24 KKK26750.1 - 2.8e-21 75.7 0.2 1.2e-20 73.7 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KKK26750.1 - 8.1e-07 28.8 0.0 1.8e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain T2SE PF00437.15 KKK26750.1 - 0.0092 14.9 0.0 0.039 12.8 0.0 2.0 2 0 0 2 2 2 1 Type II/IV secretion system protein Prp19 PF08606.6 KKK26750.1 - 0.027 14.2 0.6 0.8 9.4 0.2 2.7 2 0 0 2 2 2 0 Prp19/Pso4-like ResIII PF04851.10 KKK26750.1 - 0.032 14.0 0.0 0.31 10.8 0.0 2.5 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Cut8_C PF08559.5 KKK26751.1 - 1e-51 174.5 0.0 1.5e-51 174.0 0.0 1.2 1 0 0 1 1 1 1 Cut8 six-helix bundle Cut8_M PF14483.1 KKK26751.1 - 1.4e-13 50.4 0.8 3.2e-13 49.2 0.5 1.7 1 0 0 1 1 1 1 Cut8 dimerisation domain Cut8_N PF14482.1 KKK26751.1 - 4.8e-12 45.6 5.4 8.7e-12 44.8 3.8 1.5 1 0 0 1 1 1 1 Cut8 proteasome-binding domain Pkinase PF00069.20 KKK26752.1 - 0.00057 19.1 0.7 0.0014 17.8 0.5 1.7 1 1 0 1 1 1 1 Protein kinase domain Ank_5 PF13857.1 KKK26752.1 - 0.0024 18.0 0.0 0.0061 16.7 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.25 KKK26752.1 - 0.0079 15.9 0.2 0.02 14.6 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeat zf-C2H2_2 PF12756.2 KKK26752.1 - 0.023 14.7 1.1 0.042 13.9 0.2 1.8 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) Ank_4 PF13637.1 KKK26752.1 - 0.041 14.4 0.0 0.099 13.1 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeats (many copies) DUF2939 PF11159.3 KKK26752.1 - 0.053 13.6 0.0 0.18 11.9 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2939) Ank_2 PF12796.2 KKK26752.1 - 0.073 13.4 0.0 0.19 12.1 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) DUF3077 PF11275.3 KKK26752.1 - 0.083 12.8 0.0 0.23 11.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3077) ABC_membrane PF00664.18 KKK26753.1 - 4.2e-75 252.6 30.5 2.7e-38 131.9 8.6 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KKK26753.1 - 9e-52 175.0 0.0 2.3e-30 105.6 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 KKK26753.1 - 2.3e-09 36.8 4.0 0.0042 16.3 0.8 4.2 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 KKK26753.1 - 1.3e-06 28.5 0.6 0.01 15.8 0.2 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.1 KKK26753.1 - 8.8e-06 25.8 2.9 0.69 9.8 0.0 5.1 4 1 0 5 5 5 1 AAA domain AAA_29 PF13555.1 KKK26753.1 - 9.3e-06 25.0 0.2 0.059 12.8 0.0 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 KKK26753.1 - 4.9e-05 23.2 0.6 0.61 10.0 0.0 3.0 3 0 0 3 3 2 2 50S ribosome-binding GTPase DUF258 PF03193.11 KKK26753.1 - 5.5e-05 22.3 0.0 0.014 14.5 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 KKK26753.1 - 5.6e-05 22.6 0.0 0.17 11.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain Dynamin_N PF00350.18 KKK26753.1 - 0.00072 19.4 0.5 0.14 12.0 0.0 2.8 2 0 0 2 2 2 1 Dynamin family AAA_23 PF13476.1 KKK26753.1 - 0.0017 18.7 0.0 0.22 11.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain Miro PF08477.8 KKK26753.1 - 0.0023 18.4 0.7 3.8 8.0 0.1 2.7 2 0 0 2 2 2 2 Miro-like protein AAA_30 PF13604.1 KKK26753.1 - 0.0045 16.5 1.8 1.3 8.6 0.0 3.4 2 1 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 KKK26753.1 - 0.012 15.1 0.0 5.5 6.4 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family DUF87 PF01935.12 KKK26753.1 - 0.047 13.4 0.4 1.1 9.0 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF87 UPF0079 PF02367.12 KKK26753.1 - 0.053 13.1 0.1 0.3 10.7 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Zeta_toxin PF06414.7 KKK26753.1 - 0.069 12.2 0.2 11 5.0 0.1 2.4 2 0 0 2 2 2 0 Zeta toxin AAA_22 PF13401.1 KKK26753.1 - 0.32 11.1 2.0 17 5.5 0.0 3.3 2 1 0 2 2 2 0 AAA domain Glyco_hydro_15 PF00723.16 KKK26755.1 - 7.5e-102 341.1 3.7 5e-97 325.2 0.2 2.6 3 0 0 3 3 3 2 Glycosyl hydrolases family 15 CBM_20 PF00686.14 KKK26755.1 - 3.9e-33 112.9 0.1 1.2e-32 111.3 0.1 1.9 1 0 0 1 1 1 1 Starch binding domain CTP_transf_1 PF01148.15 KKK26756.1 - 8.2e-73 245.2 22.0 9.6e-73 245.0 15.3 1.0 1 0 0 1 1 1 1 Cytidylyltransferase family Cyclin_N PF00134.18 KKK26757.1 - 1.2e-12 47.4 0.2 1.3e-09 37.6 0.0 2.4 2 0 0 2 2 2 2 Cyclin, N-terminal domain S4 PF01479.20 KKK26758.1 - 2.2e-15 55.8 0.0 3.8e-15 55.0 0.0 1.4 1 0 0 1 1 1 1 S4 domain DUF722 PF05263.6 KKK26758.1 - 0.012 15.7 1.0 0.027 14.6 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF722) S4_2 PF13275.1 KKK26758.1 - 0.027 14.0 0.0 0.065 12.8 0.0 1.6 1 0 0 1 1 1 0 S4 domain HBS1_N PF08938.5 KKK26758.1 - 0.83 9.8 6.1 4 7.6 0.2 2.7 3 0 0 3 3 3 0 HBS1 N-terminus DUF3636 PF12331.3 KKK26759.1 - 3.6e-64 214.8 0.0 7.8e-64 213.7 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3636) IncA PF04156.9 KKK26759.1 - 1.2 8.7 6.9 2.1 7.8 4.8 1.3 1 0 0 1 1 1 0 IncA protein SelP_N PF04592.9 KKK26760.1 - 1.9 7.8 28.4 0.26 10.6 15.1 2.3 2 0 0 2 2 2 0 Selenoprotein P, N terminal region Zip PF02535.17 KKK26760.1 - 3.7 6.4 21.9 0.54 9.2 11.4 2.0 2 0 0 2 2 2 0 ZIP Zinc transporter WD40 PF00400.27 KKK26761.1 - 2e-35 119.3 6.7 5.4e-09 35.5 0.0 7.4 7 1 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 KKK26761.1 - 0.0011 18.6 0.1 0.41 10.3 0.0 2.9 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A PQQ_2 PF13360.1 KKK26761.1 - 0.021 14.3 0.0 0.23 10.8 0.0 2.3 1 1 0 1 1 1 0 PQQ-like domain Nup160 PF11715.3 KKK26761.1 - 0.058 11.5 0.0 0.23 9.5 0.0 1.9 1 1 1 2 2 2 0 Nucleoporin Nup120/160 Cornichon PF03311.9 KKK26762.1 - 8.3e-54 181.1 11.4 9.4e-54 180.9 7.9 1.0 1 0 0 1 1 1 1 Cornichon protein Peptidase_M50 PF02163.17 KKK26762.1 - 0.25 10.2 5.1 0.32 9.9 3.5 1.2 1 0 0 1 1 1 0 Peptidase family M50 3Beta_HSD PF01073.14 KKK26763.1 - 5.2e-58 195.9 0.0 6.4e-58 195.6 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 KKK26763.1 - 4.1e-37 127.8 0.0 5.2e-37 127.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 KKK26763.1 - 7.5e-19 67.6 0.0 1e-18 67.2 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 KKK26763.1 - 5.7e-15 54.9 0.0 1.3e-14 53.7 0.0 1.6 2 0 0 2 2 2 1 Male sterility protein adh_short PF00106.20 KKK26763.1 - 3.3e-11 43.4 0.1 7.2e-11 42.2 0.1 1.6 1 1 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 KKK26763.1 - 7.1e-10 39.1 0.0 9.6e-10 38.7 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 KKK26763.1 - 2.6e-09 36.4 0.0 5e-08 32.1 0.1 2.4 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein KR PF08659.5 KKK26763.1 - 1.5e-05 24.7 0.1 5.7e-05 22.8 0.1 1.8 1 1 0 1 1 1 1 KR domain Saccharop_dh PF03435.13 KKK26763.1 - 0.00076 18.5 0.0 0.0012 17.9 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NmrA PF05368.8 KKK26763.1 - 0.08 12.1 0.0 0.14 11.3 0.0 1.5 1 1 0 1 1 1 0 NmrA-like family FAD_binding_3 PF01494.14 KKK26765.1 - 9.8e-16 57.7 0.0 3e-15 56.1 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 KKK26765.1 - 5.4e-05 23.5 0.0 0.00017 21.9 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KKK26765.1 - 0.0003 20.7 0.0 0.00064 19.6 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KKK26765.1 - 0.00034 19.6 0.1 0.00076 18.4 0.1 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 KKK26765.1 - 0.0031 16.0 0.1 0.0048 15.4 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.9 KKK26765.1 - 0.0051 16.7 0.0 0.017 15.0 0.0 1.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KKK26765.1 - 0.031 13.3 3.5 0.04 12.9 0.4 2.4 2 1 0 2 2 2 0 FAD dependent oxidoreductase SE PF08491.5 KKK26765.1 - 0.033 13.0 0.0 0.044 12.5 0.0 1.2 1 0 0 1 1 1 0 Squalene epoxidase GIDA PF01134.17 KKK26765.1 - 0.056 12.2 0.1 0.098 11.5 0.1 1.5 1 1 0 1 1 1 0 Glucose inhibited division protein A FAD_binding_2 PF00890.19 KKK26765.1 - 0.058 12.2 0.3 0.16 10.7 0.1 1.7 2 0 0 2 2 2 0 FAD binding domain F-box-like PF12937.2 KKK26766.1 - 0.00086 18.9 0.5 0.0019 17.9 0.4 1.6 1 0 0 1 1 1 1 F-box-like Fungal_trans PF04082.13 KKK26767.1 - 5.1e-08 32.1 0.0 1e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DsbC_N PF10411.4 KKK26767.1 - 0.11 11.7 0.0 0.24 10.6 0.0 1.5 1 0 0 1 1 1 0 Disulfide bond isomerase protein N-terminus Glyco_hydro_25 PF01183.15 KKK26768.1 - 3e-33 115.1 0.0 4e-33 114.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 25 Thioredoxin_7 PF13899.1 KKK26768.1 - 0.063 13.3 0.0 1.7 8.6 0.1 2.3 2 0 0 2 2 2 0 Thioredoxin-like MFS_1 PF07690.11 KKK26769.1 - 1.9e-43 148.5 45.0 3.5e-43 147.6 31.2 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily Peptidase_M24 PF00557.19 KKK26769.1 - 2.7e-43 147.9 0.0 3.8e-43 147.4 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Sugar_tr PF00083.19 KKK26769.1 - 1.4e-14 53.5 9.5 1.4e-14 53.5 6.6 2.7 3 0 0 3 3 3 2 Sugar (and other) transporter zf-MYND PF01753.13 KKK26769.1 - 0.00058 19.6 4.9 0.00058 19.6 3.4 1.9 2 0 0 2 2 2 1 MYND finger EF-hand_1 PF00036.27 KKK26770.1 - 3.2e-14 51.0 2.5 8.9e-07 27.7 0.2 3.4 3 0 0 3 3 3 2 EF hand ZZ PF00569.12 KKK26770.1 - 1.3e-11 43.8 4.8 2.3e-11 43.0 3.4 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type EF-hand_7 PF13499.1 KKK26770.1 - 6.7e-11 42.1 3.0 2.4e-10 40.3 1.4 2.4 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 KKK26770.1 - 9.3e-11 40.6 2.5 0.00013 21.5 0.1 3.0 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.1 KKK26770.1 - 4e-09 35.9 3.8 8.7e-07 28.4 0.2 3.3 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.1 KKK26770.1 - 7.1e-06 25.1 5.0 0.0097 15.2 0.1 3.4 3 0 0 3 3 3 2 EF hand Mucin PF01456.12 KKK26770.1 - 9 6.0 16.3 17 5.1 11.3 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein dCMP_cyt_deam_1 PF00383.17 KKK26771.1 - 3.8e-05 23.2 0.0 0.038 13.6 0.0 2.3 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region Cyclin PF08613.6 KKK26772.1 - 2e-30 106.1 0.0 3.7e-30 105.3 0.0 1.5 1 1 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 KKK26772.1 - 4.3e-05 23.0 0.0 6.6e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain BC10 PF06726.7 KKK26773.1 - 9.9e-16 57.5 9.9 2e-15 56.5 6.9 1.5 1 0 0 1 1 1 1 Bladder cancer-related protein BC10 CorA PF01544.13 KKK26775.1 - 5.8e-10 38.6 5.4 2.1e-09 36.8 0.9 2.2 1 1 1 2 2 2 2 CorA-like Mg2+ transporter protein Gal4_dimer PF03902.8 KKK26775.1 - 0.73 9.8 3.3 0.55 10.2 0.1 2.5 3 0 0 3 3 3 0 Gal4-like dimerisation domain Chs3p PF12271.3 KKK26776.1 - 1.4e-109 365.6 5.2 1.5e-109 365.4 3.6 1.0 1 0 0 1 1 1 1 Chitin synthase III catalytic subunit DUF4149 PF13664.1 KKK26776.1 - 0.0076 16.2 1.2 0.0076 16.2 0.8 3.4 3 1 0 3 3 3 1 Domain of unknown function (DUF4149) DUF202 PF02656.10 KKK26776.1 - 0.97 9.6 0.0 0.97 9.6 0.0 4.0 2 1 0 2 2 2 0 Domain of unknown function (DUF202) Gemini_mov PF01708.11 KKK26776.1 - 3.7 7.1 9.1 6.3 6.4 0.1 3.3 3 0 0 3 3 3 0 Geminivirus putative movement protein DLH PF01738.13 KKK26777.1 - 1.4e-30 106.1 0.0 1.6e-30 106.0 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 KKK26777.1 - 1.2e-07 31.5 0.0 1.7e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.6 KKK26777.1 - 0.00016 21.4 0.0 0.18 11.5 0.0 2.1 1 1 1 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S15 PF02129.13 KKK26777.1 - 0.0071 15.8 0.0 0.0086 15.5 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.16 KKK26777.1 - 0.021 14.0 0.0 0.25 10.5 0.0 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family FSH1 PF03959.8 KKK26777.1 - 0.026 13.9 0.0 0.049 13.0 0.0 1.4 1 1 0 1 1 1 0 Serine hydrolase (FSH1) DUF2305 PF10230.4 KKK26777.1 - 0.053 12.9 0.0 0.069 12.5 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Abhydrolase_6 PF12697.2 KKK26777.1 - 0.073 12.9 0.0 4.7 7.0 0.0 2.1 1 1 1 2 2 2 0 Alpha/beta hydrolase family Arm PF00514.18 KKK26779.1 - 3.2e-19 67.9 2.5 0.00048 19.8 0.0 8.7 9 0 0 9 9 9 4 Armadillo/beta-catenin-like repeat HEAT PF02985.17 KKK26779.1 - 6.8e-05 22.6 8.7 3.7 7.8 0.0 6.3 7 0 0 7 7 7 3 HEAT repeat HEAT_2 PF13646.1 KKK26779.1 - 0.00012 22.3 1.1 0.56 10.5 0.1 4.6 4 0 0 4 4 4 2 HEAT repeats Arm_2 PF04826.8 KKK26779.1 - 0.14 11.2 0.0 6.6 5.7 0.0 2.4 2 0 0 2 2 2 0 Armadillo-like Aldo_ket_red PF00248.16 KKK26780.1 - 3.2e-58 196.8 0.0 3.6e-58 196.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family ERG4_ERG24 PF01222.12 KKK26781.1 - 3e-139 464.3 20.2 3.7e-139 463.9 14.0 1.1 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family zf-C3HC4_2 PF13923.1 KKK26781.1 - 1.2e-08 34.8 8.3 2.8e-08 33.6 5.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KKK26781.1 - 2.3e-07 30.3 5.0 4.9e-07 29.3 3.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KKK26781.1 - 2.6e-07 30.1 7.2 5.5e-07 29.1 5.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KKK26781.1 - 5.3e-07 29.3 6.9 1.2e-06 28.2 4.8 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.1 KKK26781.1 - 7.4e-06 25.7 5.7 3.6e-05 23.5 4.3 2.0 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 KKK26781.1 - 2e-05 24.2 5.0 5.4e-05 22.8 3.5 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 KKK26781.1 - 0.0031 17.1 4.4 0.0037 16.9 2.2 1.9 1 1 0 1 1 1 1 RING-type zinc-finger UCH PF00443.24 KKK26782.1 - 6.6e-50 169.7 0.0 1e-49 169.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KKK26782.1 - 1.5e-18 67.2 0.0 2.1e-13 50.4 0.0 2.1 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase APH PF01636.18 KKK26783.1 - 4.9e-08 32.9 0.1 1.4e-07 31.5 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family AMP-binding PF00501.23 KKK26784.1 - 1.7e-67 227.6 0.0 7.1e-67 225.5 0.0 1.8 2 0 0 2 2 2 1 AMP-binding enzyme AMP-binding_C PF13193.1 KKK26784.1 - 2.9e-09 37.7 0.1 5.9e-09 36.7 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Autoind_bind PF03472.10 KKK26784.1 - 0.023 13.9 0.0 0.047 12.9 0.0 1.5 1 0 0 1 1 1 0 Autoinducer binding domain Aminotran_1_2 PF00155.16 KKK26785.1 - 3.2e-42 144.7 0.0 3.9e-42 144.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 KKK26785.1 - 7.7e-09 34.7 0.0 1.3e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 KKK26785.1 - 5e-07 28.3 0.0 7.3e-07 27.7 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.16 KKK26785.1 - 6.9e-07 28.7 0.0 1.1e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 KKK26785.1 - 0.019 14.0 0.0 0.03 13.3 0.0 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Alliinase_C PF04864.8 KKK26785.1 - 0.11 11.1 0.0 0.2 10.3 0.0 1.3 1 1 0 1 1 1 0 Allinase ABC2_membrane PF01061.19 KKK26786.1 - 1.4e-36 125.6 20.9 2.6e-36 124.7 14.5 1.4 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 KKK26786.1 - 4e-25 88.6 0.0 7.4e-25 87.8 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 KKK26786.1 - 5.6e-09 36.3 0.0 1.9e-08 34.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain ABC2_membrane_3 PF12698.2 KKK26786.1 - 0.0001 21.4 27.1 0.0001 21.4 18.8 2.1 1 1 1 2 2 2 1 ABC-2 family transporter protein AAA_25 PF13481.1 KKK26786.1 - 0.00073 18.9 0.0 0.053 12.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain hEGF PF12661.2 KKK26786.1 - 0.0045 16.9 26.7 0.017 15.1 3.5 4.3 4 0 0 4 4 3 2 Human growth factor-like EGF AAA_29 PF13555.1 KKK26786.1 - 0.0053 16.2 0.1 0.011 15.2 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF258 PF03193.11 KKK26786.1 - 0.0074 15.4 0.0 0.014 14.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 KKK26786.1 - 0.01 15.9 0.0 0.027 14.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 KKK26786.1 - 0.013 15.4 0.0 0.031 14.2 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_17 PF13207.1 KKK26786.1 - 0.033 14.9 0.0 0.091 13.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 KKK26786.1 - 0.034 14.0 0.0 0.066 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 KKK26786.1 - 0.034 13.8 0.0 0.057 13.1 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase AAA_15 PF13175.1 KKK26786.1 - 0.038 13.0 0.0 3.1 6.7 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain AAA_18 PF13238.1 KKK26786.1 - 0.05 13.9 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 KKK26786.1 - 0.054 13.8 0.1 0.11 12.7 0.1 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 KKK26786.1 - 0.058 13.0 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_33 PF13671.1 KKK26786.1 - 0.086 12.7 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain cobW PF02492.14 KKK26786.1 - 0.1 12.0 0.1 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain SMC_N PF02463.14 KKK26786.1 - 0.12 11.6 0.0 2.6 7.2 0.0 2.2 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_28 PF13521.1 KKK26786.1 - 0.12 12.3 0.1 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain Laminin_EGF PF00053.19 KKK26786.1 - 1 9.3 28.8 0.51 10.3 5.5 3.7 2 1 1 3 3 3 0 Laminin EGF-like (Domains III and V) Na_H_Exchanger PF00999.16 KKK26787.1 - 4.2e-42 144.0 19.4 5.5e-42 143.6 13.4 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Cauli_VI PF01693.11 KKK26788.1 - 3e-34 116.7 11.6 3.2e-18 65.4 0.4 2.4 2 0 0 2 2 2 2 Caulimovirus viroplasmin RNase_H PF00075.19 KKK26788.1 - 1.1e-29 103.4 0.0 1.7e-29 102.7 0.0 1.3 1 0 0 1 1 1 1 RNase H Ank_2 PF12796.2 KKK26789.1 - 3.9e-05 23.9 0.0 0.081 13.2 0.0 2.4 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KKK26789.1 - 0.001 18.7 0.3 1.6 8.6 0.0 4.1 4 0 0 4 4 4 1 Ankyrin repeat Ank_4 PF13637.1 KKK26789.1 - 0.0028 18.0 0.1 2.9 8.5 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 KKK26789.1 - 0.0076 16.4 0.3 2.1 8.7 0.0 2.9 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 KKK26789.1 - 0.072 13.3 0.4 10 6.7 0.0 3.6 4 0 0 4 4 4 0 Ankyrin repeat APH PF01636.18 KKK26790.1 - 4.9e-07 29.7 0.0 7.9e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KKK26790.1 - 4.3e-05 23.2 0.0 7.4e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.15 KKK26790.1 - 0.0027 16.8 0.0 0.0099 15.0 0.0 1.8 2 0 0 2 2 2 1 Ecdysteroid kinase DUF1679 PF07914.6 KKK26790.1 - 0.011 14.4 0.0 0.016 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Ribosomal_S8 PF00410.14 KKK26791.1 - 6.9e-25 87.3 0.0 1.1e-24 86.6 0.0 1.3 1 1 0 1 1 1 1 Ribosomal protein S8 DUF1769 PF08588.5 KKK26793.1 - 1.5e-27 95.2 0.1 3e-27 94.3 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) AAA_13 PF13166.1 KKK26794.1 - 0.00025 19.6 0.0 0.00025 19.6 0.0 3.0 2 1 1 3 3 3 1 AAA domain Reo_sigmaC PF04582.7 KKK26794.1 - 0.0042 16.3 10.6 0.042 13.0 1.4 3.8 2 1 2 4 4 4 3 Reovirus sigma C capsid protein Sec3_C_2 PF15278.1 KKK26794.1 - 0.0072 16.4 0.3 0.038 14.1 0.0 2.3 2 0 0 2 2 2 1 Sec3 exocyst complex subunit ADIP PF11559.3 KKK26794.1 - 7.4 6.4 39.9 0.7 9.7 0.3 4.8 2 1 3 5 5 5 0 Afadin- and alpha -actinin-Binding Iso_dh PF00180.15 KKK26796.1 - 4.1e-96 321.9 0.0 1.3e-95 320.3 0.0 1.6 1 1 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF3506 PF12014.3 KKK26797.1 - 2.7e-51 172.9 0.0 4.9e-51 172.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3506) F-box-like PF12937.2 KKK26797.1 - 1.8e-11 43.5 0.7 4e-11 42.4 0.5 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KKK26797.1 - 9.7e-08 31.4 0.1 1e-06 28.1 0.1 2.3 2 0 0 2 2 2 1 F-box domain VRR_NUC PF08774.6 KKK26798.1 - 1e-16 60.7 0.1 4e-16 58.8 0.0 2.1 2 0 0 2 2 2 1 VRR-NUC domain Ribosomal_S13_N PF08069.7 KKK26799.1 - 9.3e-29 99.0 0.1 1.8e-28 98.1 0.1 1.5 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.17 KKK26799.1 - 1.1e-22 79.5 0.1 1.7e-22 78.9 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S15 PAX PF00292.13 KKK26799.1 - 0.015 15.0 0.1 0.035 13.8 0.0 1.6 2 0 0 2 2 2 0 'Paired box' domain YflT PF11181.3 KKK26799.1 - 0.099 12.7 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Heat induced stress protein YflT Dpy-30 PF05186.8 KKK26800.1 - 6.2e-13 48.0 0.0 7.7e-13 47.6 0.0 1.1 1 0 0 1 1 1 1 Dpy-30 motif PP1_bind PF15276.1 KKK26800.1 - 0.0088 16.0 0.1 0.018 15.0 0.0 1.6 1 1 0 1 1 1 1 Protein phosphatase 1 binding Mito_carr PF00153.22 KKK26801.1 - 4.1e-60 199.5 5.2 7.4e-21 73.6 0.0 4.1 3 1 0 3 3 3 3 Mitochondrial carrier protein TPK_catalytic PF04263.11 KKK26803.1 - 2.5e-22 78.7 0.0 8.1e-20 70.6 0.0 2.5 1 1 0 2 2 2 2 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.9 KKK26803.1 - 1.1e-19 69.8 0.0 1.9e-19 69.0 0.0 1.5 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain Apc15p PF05841.6 KKK26803.1 - 0.075 13.7 3.4 0.12 13.0 2.3 1.3 1 0 0 1 1 1 0 Apc15p protein YL1 PF05764.8 KKK26804.1 - 0.0031 17.1 3.5 0.0035 16.9 2.4 1.1 1 0 0 1 1 1 1 YL1 nuclear protein Di19_C PF14571.1 KKK26804.1 - 0.22 11.8 1.7 0.25 11.6 1.2 1.1 1 0 0 1 1 1 0 Stress-induced protein Di19, C-terminal AAA PF00004.24 KKK26805.1 - 2.3e-11 43.9 0.0 5.7e-11 42.7 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KKK26805.1 - 3.4e-07 30.4 0.0 9e-07 29.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KKK26805.1 - 4.3e-05 23.4 0.0 0.00011 22.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 KKK26805.1 - 5.6e-05 22.3 0.0 0.0001 21.4 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 KKK26805.1 - 5.9e-05 22.8 0.0 0.00013 21.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Rad17 PF03215.10 KKK26805.1 - 5.9e-05 21.9 0.0 0.00011 21.0 0.0 1.3 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_17 PF13207.1 KKK26805.1 - 0.00064 20.5 1.3 0.0021 18.8 0.0 2.5 4 0 0 4 4 2 1 AAA domain Zeta_toxin PF06414.7 KKK26805.1 - 0.0026 16.8 0.0 0.0059 15.7 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin AAA_19 PF13245.1 KKK26805.1 - 0.0028 17.3 0.0 0.0085 15.8 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_14 PF13173.1 KKK26805.1 - 0.0072 16.2 0.0 0.013 15.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 KKK26805.1 - 0.012 14.7 0.0 0.023 13.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 KKK26805.1 - 0.023 14.7 0.0 0.098 12.6 0.0 2.0 1 1 0 1 1 1 0 AAA ATPase domain IstB_IS21 PF01695.12 KKK26805.1 - 0.033 13.6 0.0 0.072 12.4 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_18 PF13238.1 KKK26805.1 - 0.063 13.5 0.0 0.17 12.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 KKK26805.1 - 0.093 11.8 0.0 0.8 8.8 0.0 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI TIP49 PF06068.8 KKK26805.1 - 0.21 10.2 0.0 0.31 9.6 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus Ribosomal_L1 PF00687.16 KKK26806.1 - 3.3e-57 193.3 6.5 3.4e-57 193.3 3.1 1.9 2 0 0 2 2 2 1 Ribosomal protein L1p/L10e family ETF PF01012.16 KKK26806.1 - 4.8e-40 136.9 2.9 4.8e-40 136.9 2.0 1.9 2 0 0 2 2 2 1 Electron transfer flavoprotein domain ETF_alpha PF00766.14 KKK26806.1 - 1e-33 114.7 0.5 2.9e-33 113.3 0.1 2.0 2 0 0 2 2 2 1 Electron transfer flavoprotein FAD-binding domain SUN PF03856.8 KKK26807.1 - 2.8e-99 331.4 14.3 5e-99 330.6 9.9 1.4 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) Fer4_10 PF13237.1 KKK26807.1 - 0.083 12.7 0.7 0.19 11.5 0.2 1.8 2 0 0 2 2 2 0 4Fe-4S dicluster domain Macoilin PF09726.4 KKK26807.1 - 3.4 5.8 5.5 4.6 5.4 3.8 1.1 1 0 0 1 1 1 0 Transmembrane protein UPF0121 PF03661.8 KKK26808.1 - 1.6e-08 34.0 0.2 1.6e-08 34.0 0.2 2.1 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0121) Septin PF00735.13 KKK26809.1 - 4.1e-124 413.1 0.1 4.1e-124 413.1 0.1 1.7 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 KKK26809.1 - 1.8e-07 31.0 0.0 3.6e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 KKK26809.1 - 5.3e-05 22.4 0.3 0.00035 19.7 0.2 2.2 1 1 0 1 1 1 1 Protein of unknown function, DUF258 ABC_tran PF00005.22 KKK26809.1 - 0.00011 22.5 2.7 0.016 15.4 0.0 3.0 2 1 0 3 3 3 1 ABC transporter GTP_EFTU PF00009.22 KKK26809.1 - 0.0002 20.8 1.6 0.0029 17.0 0.0 2.9 3 1 0 3 3 3 1 Elongation factor Tu GTP binding domain AIG1 PF04548.11 KKK26809.1 - 0.00077 18.6 1.7 0.0019 17.3 0.0 2.2 2 0 0 2 2 2 1 AIG1 family AAA_16 PF13191.1 KKK26809.1 - 0.00079 19.4 0.1 0.013 15.5 0.0 2.5 3 0 0 3 3 2 1 AAA ATPase domain AAA_10 PF12846.2 KKK26809.1 - 0.0019 17.7 3.6 0.0067 15.9 2.3 2.1 1 1 0 1 1 1 1 AAA-like domain Ras PF00071.17 KKK26809.1 - 0.0032 16.8 0.1 0.025 13.9 0.0 2.4 2 0 0 2 2 2 1 Ras family AAA_22 PF13401.1 KKK26809.1 - 0.0042 17.2 0.1 0.022 14.8 0.0 2.3 1 1 1 2 2 2 1 AAA domain Miro PF08477.8 KKK26809.1 - 0.0058 17.1 0.5 0.024 15.1 0.0 2.3 3 0 0 3 3 3 1 Miro-like protein AAA_29 PF13555.1 KKK26809.1 - 0.007 15.8 0.0 0.013 15.0 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain Dynamin_N PF00350.18 KKK26809.1 - 0.012 15.4 6.2 0.52 10.1 0.0 3.6 4 1 0 4 4 3 0 Dynamin family FtsK_SpoIIIE PF01580.13 KKK26809.1 - 0.019 14.4 2.0 0.02 14.3 0.0 2.1 3 0 0 3 3 3 0 FtsK/SpoIIIE family ATP_bind_1 PF03029.12 KKK26809.1 - 0.023 14.2 0.4 3.4 7.1 0.0 2.9 2 1 0 2 2 2 0 Conserved hypothetical ATP binding protein RNA_helicase PF00910.17 KKK26809.1 - 0.045 13.9 0.8 0.64 10.2 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA_24 PF13479.1 KKK26809.1 - 0.073 12.6 0.3 0.16 11.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 KKK26809.1 - 0.08 12.6 0.1 0.23 11.1 0.0 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B YlqD PF11068.3 KKK26809.1 - 0.18 11.8 9.4 0.41 10.6 6.5 1.6 1 0 0 1 1 1 0 YlqD protein AAA_32 PF13654.1 KKK26809.1 - 0.21 10.1 10.6 0.44 9.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain V_ATPase_I PF01496.14 KKK26809.1 - 0.41 8.4 8.1 6.4 4.5 7.3 1.6 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Phage_GPO PF05929.6 KKK26809.1 - 1.1 8.4 6.7 2 7.6 4.7 1.4 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Exonuc_VII_L PF02601.10 KKK26809.1 - 4.2 6.4 12.1 3.4 6.7 7.2 1.7 1 1 0 1 1 1 0 Exonuclease VII, large subunit IncA PF04156.9 KKK26809.1 - 7.2 6.1 10.3 12 5.4 7.2 1.4 1 0 0 1 1 1 0 IncA protein RRM_1 PF00076.17 KKK26810.1 - 8e-27 92.6 0.0 1.4e-10 40.6 0.0 3.6 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KKK26810.1 - 7.2e-21 73.9 0.0 1.2e-05 25.1 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KKK26810.1 - 3.2e-11 42.9 0.0 1.5e-06 27.8 0.0 3.3 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ufm1 PF03671.9 KKK26810.1 - 0.11 12.3 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin fold modifier 1 protein 7tm_2 PF00002.19 KKK26811.1 - 3e-06 26.4 17.3 0.0001 21.4 10.4 2.1 1 1 0 2 2 2 2 7 transmembrane receptor (Secretin family) Dicty_CAR PF05462.6 KKK26811.1 - 0.00081 18.3 19.1 0.0031 16.4 7.1 2.5 2 1 0 2 2 2 2 Slime mold cyclic AMP receptor Pyr_redox_3 PF13738.1 KKK26812.1 - 4.6e-27 95.4 0.0 2.8e-24 86.3 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KKK26812.1 - 1.4e-13 49.9 0.0 1.2e-12 46.8 0.0 2.4 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 KKK26812.1 - 8.3e-10 38.5 0.0 2.1e-09 37.2 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 KKK26812.1 - 1.4e-09 37.3 0.1 2.4e-05 23.4 0.0 3.2 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 KKK26812.1 - 4.8e-09 36.3 0.0 0.00062 19.6 0.0 2.3 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KKK26812.1 - 1.6e-06 27.2 0.0 0.0075 15.2 0.0 2.8 3 0 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KKK26812.1 - 1.4e-05 24.9 0.1 0.13 12.0 0.0 3.2 2 1 0 2 2 2 2 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 KKK26812.1 - 0.0024 16.8 0.0 0.5 9.2 0.0 2.5 2 1 0 2 2 2 2 Lycopene cyclase protein GIDA PF01134.17 KKK26812.1 - 0.014 14.2 0.0 0.35 9.6 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_binding_2 PF00890.19 KKK26812.1 - 0.049 12.4 0.0 2.3 6.9 0.0 2.5 2 0 0 2 2 2 0 FAD binding domain Thi4 PF01946.12 KKK26812.1 - 0.062 12.3 0.1 1 8.3 0.0 2.3 2 0 0 2 2 2 0 Thi4 family Mqo PF06039.10 KKK26812.1 - 0.069 11.3 0.0 0.75 7.8 0.0 2.1 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) HI0933_like PF03486.9 KKK26812.1 - 0.15 10.4 0.0 11 4.3 0.0 2.2 2 0 0 2 2 2 0 HI0933-like protein OGG_N PF07934.7 KKK26813.1 - 7.3e-37 125.9 0.1 1.6e-36 124.7 0.0 1.6 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.20 KKK26813.1 - 4.7e-17 62.2 0.0 8.1e-17 61.4 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 KKK26813.1 - 0.061 13.0 0.0 0.14 11.8 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif PIG-S PF10510.4 KKK26813.1 - 1.7 7.2 4.6 2.1 6.8 3.2 1.1 1 0 0 1 1 1 0 Phosphatidylinositol-glycan biosynthesis class S protein Rax2 PF12768.2 KKK26814.1 - 2.1e-107 358.5 20.0 4e-98 328.0 0.0 5.2 4 2 1 5 5 5 5 Cortical protein marker for cell polarity WD40 PF00400.27 KKK26814.1 - 0.11 12.4 1.3 38 4.3 0.0 4.1 4 0 0 4 4 4 0 WD domain, G-beta repeat Fungal_trans_2 PF11951.3 KKK26815.1 - 1.9e-09 36.6 0.0 9.2e-09 34.3 0.0 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK26815.1 - 2.2e-07 30.6 12.6 3.7e-07 29.9 8.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CheD PF03975.8 KKK26815.1 - 0.17 11.6 0.0 0.34 10.6 0.0 1.4 1 0 0 1 1 1 0 CheD chemotactic sensory transduction SSrecog PF03531.9 KKK26816.1 - 1.8e-64 217.1 0.1 1.6e-63 214.0 0.1 2.2 1 1 0 1 1 1 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.7 KKK26816.1 - 1.3e-28 98.7 0.0 1.8e-27 95.1 0.0 2.5 3 0 0 3 3 3 1 Histone chaperone Rttp106-like BSP_II PF05432.6 KKK26816.1 - 7.2 5.7 26.9 7 5.8 12.0 2.4 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) Asp PF00026.18 KKK26817.1 - 1.8e-28 99.7 0.7 2.4e-28 99.3 0.5 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KKK26817.1 - 0.027 14.4 0.1 0.11 12.4 0.0 2.1 1 1 1 2 2 2 0 Xylanase inhibitor N-terminal Glyco_hydro_16 PF00722.16 KKK26818.1 - 1.2e-40 138.7 4.5 2.1e-40 138.0 3.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 DAHP_synth_2 PF01474.11 KKK26819.1 - 7.7e-140 466.1 0.0 8.7e-140 465.9 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family Ribosomal_L15e PF00827.12 KKK26820.1 - 2e-06 27.4 0.2 2e-06 27.4 0.1 1.0 1 0 0 1 1 1 1 Ribosomal L15 PfkB PF00294.19 KKK26821.1 - 2.6e-20 72.7 0.0 3.2e-20 72.4 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase HSDR_N_2 PF13588.1 KKK26821.1 - 0.12 12.1 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Type I restriction enzyme R protein N terminus (HSDR_N) Tau95 PF09734.4 KKK26822.1 - 6.7e-82 275.2 0.0 8.2e-82 274.9 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit adh_short PF00106.20 KKK26824.1 - 8.5e-17 61.5 0.0 2.3e-16 60.1 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KKK26824.1 - 8.8e-09 35.2 0.0 1.3e-08 34.7 0.0 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KKK26824.1 - 2.4e-06 27.4 0.0 5.5e-06 26.3 0.0 1.5 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KKK26824.1 - 0.13 11.6 0.0 0.25 10.7 0.0 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family GMC_oxred_N PF00732.14 KKK26825.1 - 4.6e-60 203.2 0.0 5.7e-60 202.9 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KKK26825.1 - 2.2e-30 105.8 0.0 3.9e-30 105.0 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 KKK26825.1 - 1.2e-07 30.9 1.2 0.00074 18.5 0.6 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KKK26825.1 - 6.9e-06 25.1 0.5 0.038 12.8 0.2 2.1 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 KKK26825.1 - 0.0022 17.9 0.2 0.0068 16.4 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 KKK26825.1 - 0.0034 16.3 0.3 0.0061 15.5 0.2 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.12 KKK26825.1 - 0.039 13.0 0.1 0.067 12.2 0.1 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.1 KKK26825.1 - 0.13 12.2 0.0 2 8.4 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_DMAT PF11991.3 KKK26826.1 - 0.00067 18.9 0.0 0.00085 18.6 0.0 1.2 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase SHS2_Rpb7-N PF03876.12 KKK26827.1 - 2.5e-07 30.6 0.0 5e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 Dicty_REP PF05086.7 KKK26827.1 - 0.0026 15.6 1.5 0.0026 15.6 1.1 2.0 2 0 0 2 2 2 1 Dictyostelium (Slime Mold) REP protein Mucin PF01456.12 KKK26827.1 - 0.008 15.9 7.0 0.008 15.9 4.9 2.5 2 0 0 2 2 2 1 Mucin-like glycoprotein U79_P34 PF03064.11 KKK26827.1 - 0.2 11.1 7.6 5.8 6.3 6.9 2.1 2 0 0 2 2 2 0 HSV U79 / HCMV P34 DUF702 PF05142.7 KKK26827.1 - 0.25 11.5 6.9 6.4 6.9 2.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF702) Menin PF05053.8 KKK26827.1 - 0.35 8.9 13.3 0.17 9.9 1.5 2.1 2 0 0 2 2 2 0 Menin NP1-WLL PF11733.3 KKK26827.1 - 0.62 10.3 21.3 2.2 8.5 7.9 2.4 2 0 0 2 2 2 0 Non-capsid protein NP1 DUF3439 PF11921.3 KKK26827.1 - 1 9.1 13.8 0.34 10.6 4.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) DUF4544 PF15077.1 KKK26827.1 - 8 5.8 8.3 2.1 7.7 3.4 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4544) AJAP1_PANP_C PF15298.1 KKK26827.1 - 9.2 6.0 15.4 0.32 10.8 5.0 2.2 2 0 0 2 2 2 0 AJAP1/PANP C-terminus Pyr_redox_2 PF07992.9 KKK26828.1 - 8.2e-27 94.4 0.1 2.3e-26 92.9 0.0 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.21 KKK26828.1 - 1.4e-14 53.3 0.1 3.6e-14 52.1 0.1 1.6 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pyr_redox PF00070.22 KKK26828.1 - 8.4e-10 38.9 0.2 3.4e-08 33.7 0.0 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Rieske_2 PF13806.1 KKK26828.1 - 3.9e-05 23.3 0.0 0.00016 21.3 0.0 2.1 2 0 0 2 2 2 1 Rieske-like [2Fe-2S] domain Reductase_C PF14759.1 KKK26828.1 - 9.6e-05 22.6 0.1 0.00057 20.1 0.0 2.3 2 0 0 2 2 2 1 Reductase C-terminal DUF1188 PF06690.6 KKK26828.1 - 0.034 13.2 0.2 0.14 11.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1188) NAD_binding_9 PF13454.1 KKK26828.1 - 0.059 13.1 1.3 9 6.0 0.0 3.4 3 0 0 3 3 3 0 FAD-NAD(P)-binding PQQ_3 PF13570.1 KKK26828.1 - 0.1 12.9 1.1 19 5.7 0.0 3.1 2 0 0 2 2 2 0 PQQ-like domain SDA1 PF05285.7 KKK26828.1 - 2.8 7.1 31.5 2.5 7.3 16.3 2.7 1 1 1 2 2 2 0 SDA1 F-box-like PF12937.2 KKK26829.1 - 0.0058 16.3 0.1 0.015 14.9 0.1 1.7 1 0 0 1 1 1 1 F-box-like Arrestin_N PF00339.24 KKK26830.1 - 5.4e-15 55.5 0.5 1.6e-10 41.0 0.0 2.8 3 0 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain Rgp1 PF08737.5 KKK26830.1 - 0.015 14.4 0.2 0.027 13.5 0.1 1.5 1 0 0 1 1 1 0 Rgp1 Bul1_C PF04426.7 KKK26830.1 - 0.068 12.3 0.0 0.13 11.3 0.0 1.4 1 0 0 1 1 1 0 Bul1 C terminus PGAP1 PF07819.8 KKK26831.1 - 0.088 12.3 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Zn_clus PF00172.13 KKK26832.1 - 0.00027 20.8 2.8 0.00027 20.8 2.0 2.4 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KKK26832.1 - 0.002 16.7 0.0 0.0031 16.1 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Nucleopor_Nup85 PF07575.8 KKK26833.1 - 4.3e-18 64.8 0.0 5.1e-09 34.8 0.0 2.9 2 1 0 2 2 2 2 Nup85 Nucleoporin Daxx PF03344.10 KKK26833.1 - 0.53 8.7 4.2 1 7.7 2.9 1.4 1 0 0 1 1 1 0 Daxx Family TPR_11 PF13414.1 KKK26834.1 - 4.3e-12 45.4 2.9 5.8e-09 35.4 0.1 2.5 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 KKK26834.1 - 1.4e-07 30.9 4.3 0.043 13.7 0.2 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat LRR_8 PF13855.1 KKK26834.1 - 4.6e-07 29.4 3.4 0.026 14.2 0.2 5.7 4 3 2 6 6 6 1 Leucine rich repeat F-box PF00646.28 KKK26834.1 - 2.3e-06 27.0 0.2 7.8e-06 25.4 0.2 1.9 1 0 0 1 1 1 1 F-box domain TPR_1 PF00515.23 KKK26834.1 - 3.2e-06 26.5 3.0 0.65 9.7 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 KKK26834.1 - 5e-06 27.0 1.4 0.0028 18.3 0.1 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat LRR_7 PF13504.1 KKK26834.1 - 0.00049 19.8 1.4 22 5.8 0.0 7.1 8 0 0 8 8 6 0 Leucine rich repeat TPR_12 PF13424.1 KKK26834.1 - 0.0012 18.7 4.8 0.027 14.4 0.7 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat BTAD PF03704.12 KKK26834.1 - 0.0015 18.8 1.1 0.015 15.5 0.1 2.1 1 1 1 2 2 2 1 Bacterial transcriptional activator domain Apc3 PF12895.2 KKK26834.1 - 0.0017 18.4 1.6 0.26 11.4 0.2 2.3 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 KKK26834.1 - 0.0022 18.2 2.7 0.012 15.8 0.6 2.3 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 KKK26834.1 - 0.0024 18.3 3.1 3.3 8.5 0.3 3.5 1 1 2 3 3 3 1 Tetratricopeptide repeat F-box-like PF12937.2 KKK26834.1 - 0.004 16.8 0.2 0.0078 15.9 0.1 1.5 1 0 0 1 1 1 1 F-box-like LRR_6 PF13516.1 KKK26834.1 - 0.0059 16.5 11.9 38 4.7 0.0 7.6 8 0 0 8 8 8 0 Leucine Rich repeat NARP1 PF12569.3 KKK26834.1 - 0.011 14.4 1.9 0.015 14.0 1.3 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 TPR_7 PF13176.1 KKK26834.1 - 0.029 14.1 1.6 12 5.9 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat PRANC PF09372.5 KKK26834.1 - 0.03 14.2 0.0 0.06 13.3 0.0 1.5 1 0 0 1 1 1 0 PRANC domain TPR_9 PF13371.1 KKK26834.1 - 0.075 12.8 1.4 13 5.7 0.2 3.2 1 1 2 3 3 3 0 Tetratricopeptide repeat DUF742 PF05331.6 KKK26834.1 - 0.11 12.1 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF742) TPR_15 PF13429.1 KKK26834.1 - 0.15 11.1 4.1 31 3.4 0.1 2.0 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_6 PF13174.1 KKK26834.1 - 2.6 8.6 5.5 4 8.1 0.1 2.8 3 0 0 3 3 2 0 Tetratricopeptide repeat ADIP PF11559.3 KKK26835.1 - 6.3e-44 149.5 6.9 6.3e-44 149.5 4.8 3.1 4 0 0 4 4 4 1 Afadin- and alpha -actinin-Binding TBPIP PF07106.8 KKK26835.1 - 0.0018 17.8 7.9 0.2 11.1 4.9 2.6 2 0 0 2 2 2 2 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) AAA_13 PF13166.1 KKK26835.1 - 0.0045 15.5 1.9 0.009 14.5 1.3 1.5 1 0 0 1 1 1 1 AAA domain Spc7 PF08317.6 KKK26835.1 - 0.02 13.5 6.3 0.047 12.3 4.4 1.6 1 0 0 1 1 1 0 Spc7 kinetochore protein FlaC_arch PF05377.6 KKK26835.1 - 0.42 10.5 2.6 1.7 8.5 0.2 2.9 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) HAUS-augmin3 PF14932.1 KKK26835.1 - 0.89 8.6 11.9 0.31 10.2 5.1 2.5 3 0 0 3 3 3 0 HAUS augmin-like complex subunit 3 V-ATPase_G PF03179.10 KKK26836.1 - 3.1e-34 117.4 16.7 3.7e-34 117.1 11.6 1.1 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit ATP-synt_B PF00430.13 KKK26836.1 - 0.05 13.4 19.9 0.029 14.1 7.6 2.1 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) DUF29 PF01724.11 KKK26836.1 - 0.064 13.0 3.1 0.086 12.6 2.1 1.3 1 0 0 1 1 1 0 Domain of unknown function DUF29 Colicin-DNase PF12639.2 KKK26836.1 - 0.12 12.6 6.2 0.21 11.8 4.4 1.4 1 1 0 1 1 1 0 DNase/tRNase domain of colicin-like bacteriocin ECM11 PF15463.1 KKK26836.1 - 0.2 11.9 8.4 0.33 11.2 5.8 1.4 1 0 0 1 1 1 0 Extracellular mutant protein 11 Clathrin_lg_ch PF01086.12 KKK26836.1 - 0.24 11.2 11.7 0.3 10.9 8.1 1.0 1 0 0 1 1 1 0 Clathrin light chain CAF-1_p150 PF11600.3 KKK26836.1 - 0.35 10.2 21.9 0.43 9.9 15.2 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal S_layer_C PF05124.7 KKK26836.1 - 0.4 10.2 5.3 0.45 10.0 3.7 1.1 1 0 0 1 1 1 0 S-layer like family, C-terminal region Endonuc_Holl PF10107.4 KKK26836.1 - 0.43 10.2 7.6 0.54 9.9 5.0 1.4 1 1 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase DNA_primase_lrg PF04104.9 KKK26836.1 - 0.55 9.4 3.8 0.63 9.2 2.6 1.1 1 0 0 1 1 1 0 Eukaryotic and archaeal DNA primase, large subunit DUF3552 PF12072.3 KKK26836.1 - 0.86 8.7 20.7 0.29 10.3 10.7 1.9 1 1 2 3 3 3 0 Domain of unknown function (DUF3552) DUF2870 PF11069.3 KKK26836.1 - 1.2 9.1 7.5 2.1 8.4 5.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2870) DUF4604 PF15377.1 KKK26836.1 - 1.3 9.2 15.5 1.7 8.8 10.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) AIF-MLS PF14962.1 KKK26836.1 - 1.6 8.3 9.5 1.8 8.1 6.6 1.2 1 0 0 1 1 1 0 Mitochondria Localisation Sequence DUF2151 PF10221.4 KKK26836.1 - 1.7 6.7 8.9 1.9 6.5 6.2 1.0 1 0 0 1 1 1 0 Cell cycle and development regulator Nucleoporin2 PF04096.9 KKK26836.1 - 2.4 7.9 6.1 14 5.5 2.1 2.1 1 1 1 2 2 2 0 Nucleoporin autopeptidase HrpE PF06188.7 KKK26836.1 - 3 7.5 8.1 8.4 6.0 5.6 1.8 1 1 0 1 1 1 0 HrpE/YscL/FliH and V-type ATPase subunit E RRF PF01765.14 KKK26836.1 - 3.5 7.0 14.0 5.4 6.4 9.7 1.2 1 0 0 1 1 1 0 Ribosome recycling factor Vfa1 PF08432.5 KKK26836.1 - 3.8 7.5 13.6 4.3 7.3 9.4 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 OmpH PF03938.9 KKK26836.1 - 4.4 7.2 13.3 5.3 6.9 9.2 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) KfrA_N PF11740.3 KKK26836.1 - 4.5 7.7 10.4 0.5 10.8 3.3 2.0 1 1 1 2 2 2 0 Plasmid replication region DNA-binding N-term Muted PF14942.1 KKK26836.1 - 8.3 6.2 13.4 3.3 7.5 7.0 1.7 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein DUF883 PF05957.8 KKK26836.1 - 8.7 6.8 9.5 46 4.4 6.3 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF106 PF01956.11 KKK26837.1 - 0.055 13.0 0.3 0.064 12.7 0.2 1.0 1 0 0 1 1 1 0 Integral membrane protein DUF106 DUF3824 PF12868.2 KKK26837.1 - 0.081 13.8 0.1 0.11 13.4 0.1 1.3 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) IDO PF01231.13 KKK26838.1 - 4.4e-39 134.0 0.0 7.1e-39 133.4 0.0 1.2 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase DnaJ PF00226.26 KKK26839.1 - 3.2e-10 39.5 0.0 7.8e-10 38.3 0.0 1.7 1 0 0 1 1 1 1 DnaJ domain INO80_Ies4 PF08193.6 KKK26840.1 - 2.3e-85 286.0 23.6 1e-84 283.9 16.3 1.8 1 1 0 1 1 1 1 INO80 complex subunit Ies4 DUF3439 PF11921.3 KKK26841.1 - 1.1 9.0 5.0 1.9 8.2 3.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) 4HBT PF03061.17 KKK26842.1 - 2.5e-13 49.9 0.0 4.3e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily Glyco_hydro_92 PF07971.7 KKK26843.1 - 4.6e-171 569.8 0.0 5.9e-171 569.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 DUF3431 PF11913.3 KKK26844.1 - 2.7e-90 301.7 0.0 3.4e-90 301.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) RNase_P_p30 PF01876.11 KKK26845.1 - 3.9e-47 159.2 0.0 5.4e-47 158.7 0.0 1.2 1 0 0 1 1 1 1 RNase P subunit p30 tRNA-synt_1 PF00133.17 KKK26847.1 - 9.5e-219 727.3 0.0 5.1e-218 724.9 0.0 1.9 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 KKK26847.1 - 8.8e-34 116.4 1.0 8.8e-34 116.4 0.7 2.1 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 KKK26847.1 - 1.8e-15 56.5 0.3 2.9e-06 26.2 0.0 5.3 4 2 1 5 5 5 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 KKK26847.1 - 1.4e-08 34.2 0.0 4.3e-05 22.8 0.0 2.7 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.14 KKK26847.1 - 0.03 13.4 0.0 0.19 10.8 0.0 2.1 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain HR1 PF02185.11 KKK26847.1 - 9.2 6.0 11.8 0.054 13.2 1.7 2.1 2 0 0 2 2 2 0 Hr1 repeat Pkinase PF00069.20 KKK26848.1 - 1.6e-60 204.4 0.0 1.9e-60 204.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK26848.1 - 4.5e-20 71.8 0.0 6.3e-20 71.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KKK26848.1 - 2.5e-08 33.9 0.4 9.7e-05 22.2 0.1 2.7 2 1 1 3 3 3 2 Phosphotransferase enzyme family Choline_kinase PF01633.15 KKK26848.1 - 0.0075 15.8 0.0 0.015 14.8 0.0 1.7 1 1 0 1 1 1 1 Choline/ethanolamine kinase Kinase-like PF14531.1 KKK26848.1 - 0.021 13.7 0.0 0.035 13.0 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.9 KKK26848.1 - 0.032 13.2 0.0 0.05 12.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KKK26848.1 - 0.062 12.6 0.1 0.11 11.7 0.1 1.4 1 0 0 1 1 1 0 RIO1 family MFS_1 PF07690.11 KKK26849.1 - 7.1e-20 71.0 28.6 1.8e-10 40.0 0.9 3.1 3 0 0 3 3 3 3 Major Facilitator Superfamily MFS_2 PF13347.1 KKK26849.1 - 2.9e-08 32.5 5.4 4.5e-06 25.3 1.3 2.5 2 1 0 2 2 2 2 MFS/sugar transport protein MFS_1_like PF12832.2 KKK26849.1 - 0.0002 21.0 3.0 0.17 11.7 0.1 3.5 3 0 0 3 3 3 2 MFS_1 like family zf-rbx1 PF12678.2 KKK26850.1 - 1.4e-11 44.3 2.1 3.2e-11 43.1 1.5 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 KKK26850.1 - 1.2e-10 41.0 7.0 4.6e-10 39.1 4.9 2.0 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 KKK26850.1 - 5.4e-07 29.1 4.5 9.1e-06 25.2 1.2 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KKK26850.1 - 7.8e-07 28.6 3.2 1.6e-06 27.6 2.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KKK26850.1 - 6.3e-06 25.8 1.6 1.5e-05 24.6 1.1 1.6 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KKK26850.1 - 1.3e-05 25.0 2.1 1.3e-05 25.0 1.4 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KKK26850.1 - 1.9e-05 24.2 3.9 3.9e-05 23.2 2.7 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-Apc11 PF12861.2 KKK26850.1 - 0.0077 16.0 4.3 0.038 13.8 3.0 2.0 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.1 KKK26850.1 - 0.02 14.7 1.3 0.05 13.4 0.9 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING CopD PF05425.8 KKK26850.1 - 1.1 9.5 9.9 0.44 10.7 3.8 2.2 1 1 1 2 2 2 0 Copper resistance protein D zf-RING_4 PF14570.1 KKK26850.1 - 1.9 8.1 4.8 0.61 9.7 1.2 1.7 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Ureidogly_hydro PF04115.7 KKK26851.1 - 1.1e-51 174.4 0.0 1.2e-25 89.8 0.0 2.1 2 0 0 2 2 2 2 Ureidoglycolate hydrolase Myc_N PF01056.13 KKK26851.1 - 0.022 13.9 0.5 0.031 13.4 0.3 1.2 1 0 0 1 1 1 0 Myc amino-terminal region TraV PF09676.5 KKK26851.1 - 1.1 9.9 4.6 0.18 12.5 0.5 1.6 2 0 0 2 2 2 0 Type IV conjugative transfer system lipoprotein (TraV) MutS_V PF00488.16 KKK26852.1 - 1.3e-83 280.0 0.0 2e-83 279.3 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 KKK26852.1 - 3.2e-41 141.3 5.2 6.6e-41 140.3 3.6 1.6 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 KKK26852.1 - 3.1e-21 75.5 0.0 1e-20 73.8 0.0 1.9 1 0 0 1 1 1 1 MutS domain I MutS_IV PF05190.13 KKK26852.1 - 0.0011 19.1 0.0 0.0024 17.9 0.0 1.7 1 0 0 1 1 1 1 MutS family domain IV AAA_23 PF13476.1 KKK26852.1 - 0.02 15.2 0.2 0.7 10.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 KKK26852.1 - 0.027 14.0 0.0 0.064 12.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Sec63 PF02889.11 KKK26853.1 - 1.1e-193 642.4 0.0 7e-107 357.2 0.0 2.4 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 KKK26853.1 - 1.2e-53 181.0 0.1 8.1e-31 106.7 0.0 3.5 3 0 0 3 3 3 2 DEAD/DEAH box helicase Peptidase_S9 PF00326.16 KKK26853.1 - 3.6e-49 166.8 0.0 9.5e-49 165.5 0.0 1.7 1 0 0 1 1 1 1 Prolyl oligopeptidase family ResIII PF04851.10 KKK26853.1 - 6.4e-16 58.7 0.0 7.6e-07 29.1 0.0 2.5 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.26 KKK26853.1 - 3.4e-09 36.4 0.0 1.5e-08 34.3 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Abhydrolase_5 PF12695.2 KKK26853.1 - 6.6e-09 35.6 0.0 2.2e-08 34.0 0.0 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family AAA_22 PF13401.1 KKK26853.1 - 1.4e-05 25.2 0.8 0.055 13.6 0.1 3.7 3 1 0 3 3 3 2 AAA domain PhoH PF02562.11 KKK26853.1 - 0.0012 18.1 0.0 0.16 11.2 0.0 2.6 2 0 0 2 2 2 1 PhoH-like protein AAA_19 PF13245.1 KKK26853.1 - 0.0017 18.0 0.0 0.11 12.3 0.0 2.7 2 0 0 2 2 2 1 Part of AAA domain AXE1 PF05448.7 KKK26853.1 - 0.0018 16.8 0.0 0.11 11.0 0.0 2.6 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) AAA_10 PF12846.2 KKK26853.1 - 0.0023 17.3 0.1 6.9 6.0 0.0 4.0 4 0 0 4 4 4 1 AAA-like domain T2SE PF00437.15 KKK26853.1 - 0.0051 15.7 0.0 1 8.1 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein IstB_IS21 PF01695.12 KKK26853.1 - 0.031 13.6 0.1 3.2 7.1 0.0 3.1 3 0 0 3 3 3 0 IstB-like ATP binding protein AMP-binding PF00501.23 KKK26855.1 - 2.9e-42 144.5 0.0 3e-41 141.2 0.0 2.1 1 1 0 1 1 1 1 AMP-binding enzyme FeoA PF04023.9 KKK26855.1 - 0.073 13.0 0.0 0.22 11.4 0.0 1.8 1 0 0 1 1 1 0 FeoA domain HTH_AsnC-type PF13404.1 KKK26856.1 - 0.04 13.4 0.1 0.082 12.4 0.1 1.5 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain MFS_1 PF07690.11 KKK26857.1 - 6.2e-39 133.7 43.8 6.2e-39 133.7 30.4 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KKK26857.1 - 7.4e-19 67.3 11.2 1.8e-18 66.0 7.7 1.6 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 KKK26857.1 - 5.2e-14 51.6 15.4 2.5e-12 46.1 4.6 2.6 2 0 0 2 2 2 2 Sugar (and other) transporter ADH_N PF08240.7 KKK26858.1 - 9.6e-27 92.9 4.4 1.5e-26 92.2 3.1 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KKK26858.1 - 1.2e-15 57.2 0.0 2e-15 56.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_10 PF13460.1 KKK26858.1 - 0.0076 16.2 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding ELFV_dehydrog PF00208.16 KKK26858.1 - 0.0078 15.8 0.1 0.013 15.1 0.1 1.2 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ADH_zinc_N_2 PF13602.1 KKK26858.1 - 0.01 16.7 0.0 0.031 15.1 0.0 1.8 2 0 0 2 2 2 0 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 KKK26858.1 - 0.017 14.2 0.0 0.026 13.6 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GCC2_GCC3 PF07699.8 KKK26858.1 - 0.058 12.9 1.5 0.3 10.7 0.6 2.2 2 0 0 2 2 2 0 GCC2 and GCC3 Brix PF04427.13 KKK26859.1 - 2.3e-33 115.4 0.0 2.9e-33 115.1 0.0 1.1 1 0 0 1 1 1 1 Brix domain Tim17 PF02466.14 KKK26860.1 - 3.3e-25 88.5 0.4 3.3e-25 88.5 0.3 1.5 2 0 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family DUF2207 PF09972.4 KKK26860.1 - 0.071 11.6 0.3 0.073 11.6 0.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF2697 PF10906.3 KKK26861.1 - 0.00015 21.6 0.0 0.0002 21.2 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF2697) Y_phosphatase PF00102.22 KKK26862.1 - 4.9e-52 176.6 0.0 2.4e-51 174.3 0.0 1.8 1 1 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 KKK26862.1 - 0.0016 18.4 0.0 0.0062 16.5 0.0 1.9 2 0 0 2 2 2 1 Inositol hexakisphosphate DSPc PF00782.15 KKK26862.1 - 0.0075 15.8 0.0 0.021 14.4 0.0 1.7 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 KKK26862.1 - 0.029 14.6 0.0 0.059 13.6 0.0 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family Mid2 PF04478.7 KKK26864.1 - 3e-06 26.7 4.1 3e-06 26.7 2.9 3.3 1 1 2 3 3 3 1 Mid2 like cell wall stress sensor DUF4345 PF14248.1 KKK26864.1 - 0.018 14.4 0.4 0.35 10.3 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4345) Mitofilin PF09731.4 KKK26864.1 - 0.19 10.3 6.6 0.22 10.1 4.6 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Macoilin PF09726.4 KKK26864.1 - 0.37 9.0 20.8 0.44 8.7 14.4 1.1 1 0 0 1 1 1 0 Transmembrane protein Hid1 PF12722.2 KKK26864.1 - 0.67 7.5 14.4 0.83 7.2 10.0 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein GCOM2 PF15328.1 KKK26864.1 - 2.5 7.7 10.4 3.3 7.3 7.2 1.2 1 0 0 1 1 1 0 Putative GRINL1B complex locus protein 2 Utp14 PF04615.8 KKK26864.1 - 2.6 6.1 7.1 3 5.9 4.9 1.1 1 0 0 1 1 1 0 Utp14 protein DUF572 PF04502.8 KKK26864.1 - 3.8 6.6 15.5 5 6.2 10.8 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) KIAA1328 PF15369.1 KKK26864.1 - 6.5 6.4 13.0 8.2 6.1 9.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein KIAA1328 PAP1 PF08601.5 KKK26864.1 - 6.9 6.2 36.5 9.6 5.7 25.3 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 Piwi PF02171.12 KKK26865.1 - 2.3e-68 230.4 0.0 3.3e-68 229.8 0.0 1.2 1 0 0 1 1 1 1 Piwi domain DUF1785 PF08699.5 KKK26865.1 - 2.7e-19 68.2 0.0 6.6e-19 67.0 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) PAZ PF02170.17 KKK26865.1 - 3e-17 62.2 0.0 5.3e-17 61.3 0.0 1.4 1 0 0 1 1 1 1 PAZ domain Suf PF05843.9 KKK26866.1 - 1.8e-92 310.0 0.1 1.8e-92 310.0 0.1 4.1 4 1 0 4 4 4 1 Suppressor of forked protein (Suf) TPR_14 PF13428.1 KKK26866.1 - 8.1e-05 22.9 0.0 0.015 15.8 0.0 3.7 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 KKK26866.1 - 0.00078 20.0 0.1 0.011 16.3 0.0 2.8 2 1 1 3 3 3 1 Tetratricopeptide repeat HAT PF02184.11 KKK26866.1 - 0.0052 16.4 0.1 0.0052 16.4 0.0 2.4 2 0 0 2 2 2 1 HAT (Half-A-TPR) repeat Bromodomain PF00439.20 KKK26867.1 - 2.7e-19 68.8 4.1 1.3e-18 66.6 0.2 3.3 3 0 0 3 3 3 1 Bromodomain Bromo_TP PF07524.8 KKK26867.1 - 3.7e-09 36.1 0.0 2.2e-08 33.7 0.0 2.3 2 0 0 2 2 2 1 Bromodomain associated HisKA_3 PF07730.8 KKK26867.1 - 0.0077 16.5 0.9 0.19 12.1 0.0 3.1 2 0 0 2 2 2 1 Histidine kinase bZIP_1 PF00170.16 KKK26868.1 - 4.5e-05 23.3 8.5 4.5e-05 23.3 5.9 1.6 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 KKK26868.1 - 0.0014 18.3 8.9 0.0033 17.2 6.2 1.6 1 0 0 1 1 1 1 Basic region leucine zipper Fib_alpha PF08702.5 KKK26868.1 - 0.08 13.0 0.7 0.15 12.1 0.5 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF4407 PF14362.1 KKK26868.1 - 0.12 11.2 2.0 0.2 10.5 1.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Glutaredoxin2_C PF04399.8 KKK26868.1 - 0.14 11.7 0.5 0.23 11.0 0.4 1.3 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain Pex19 PF04614.7 KKK26869.1 - 5.6e-69 232.5 13.3 1e-68 231.6 9.2 1.5 1 1 0 1 1 1 1 Pex19 protein family Ebola_NP PF05505.7 KKK26869.1 - 0.056 11.5 1.8 0.07 11.1 1.2 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein T2SF PF00482.18 KKK26869.1 - 0.65 9.9 2.5 11 5.9 0.1 3.1 4 1 0 4 4 4 0 Type II secretion system (T2SS), protein F FliE PF02049.13 KKK26869.1 - 1.6 8.7 7.5 0.55 10.2 0.4 3.2 1 1 3 4 4 4 0 Flagellar hook-basal body complex protein FliE VanZ PF04892.7 KKK26870.1 - 7.1e-10 38.9 0.5 1.1e-09 38.3 0.3 1.3 1 0 0 1 1 1 1 VanZ like family DUF4401 PF14351.1 KKK26870.1 - 0.0051 15.8 0.1 0.0065 15.5 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4401) FtsX PF02687.16 KKK26870.1 - 0.03 14.0 1.8 2.7 7.7 0.5 2.3 2 1 0 2 2 2 0 FtsX-like permease family DUF4131 PF13567.1 KKK26870.1 - 7.9 5.8 7.7 42 3.4 0.1 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) Stm1_N PF09598.5 KKK26871.1 - 2.9e-18 66.3 4.4 2.9e-18 66.3 3.0 4.5 3 2 0 3 3 3 1 Stm1 Ribosomal_L14e PF01929.12 KKK26871.1 - 1.4 9.3 5.3 4.9 7.5 0.9 2.3 2 0 0 2 2 2 0 Ribosomal protein L14 KR PF08659.5 KKK26873.1 - 5.6e-51 172.7 4.3 9.3e-51 172.0 0.4 2.9 3 0 0 3 3 3 1 KR domain PS-DH PF14765.1 KKK26873.1 - 1.6e-49 168.6 1.5 1.6e-49 168.6 1.0 1.8 2 0 0 2 2 2 1 Polyketide synthase dehydratase adh_short PF00106.20 KKK26873.1 - 4.8e-45 153.4 4.5 8.3e-45 152.6 0.7 3.1 2 0 0 2 2 2 1 short chain dehydrogenase PP-binding PF00550.20 KKK26873.1 - 2e-05 24.7 0.1 6.3e-05 23.1 0.1 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site ASF1_hist_chap PF04729.8 KKK26874.1 - 1.3e-67 226.2 0.0 1.8e-67 225.7 0.0 1.2 1 0 0 1 1 1 1 ASF1 like histone chaperone Nop14 PF04147.7 KKK26874.1 - 0.0014 16.6 14.0 0.0019 16.2 9.7 1.1 1 0 0 1 1 1 1 Nop14-like family GCP5-Mod21 PF14609.1 KKK26874.1 - 1.5 6.8 6.2 1.9 6.4 4.3 1.1 1 0 0 1 1 1 0 gamma-Tubulin ring complex non-core subunit mod21 Lgl_C PF08596.5 KKK26875.1 - 9.2e-136 452.3 0.0 2e-135 451.2 0.0 1.6 2 0 0 2 2 2 1 Lethal giant larvae(Lgl) like, C-terminal WD40 PF00400.27 KKK26875.1 - 0.00033 20.4 1.1 2.6 8.0 0.1 5.0 6 0 0 6 6 6 2 WD domain, G-beta repeat adh_short PF00106.20 KKK26876.1 - 3.6e-24 85.5 3.0 5.6e-24 84.9 2.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KKK26876.1 - 5.6e-15 55.7 0.0 7.9e-15 55.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 KKK26876.1 - 3e-07 30.6 0.5 6.5e-07 29.5 0.3 1.6 1 1 0 1 1 1 1 NADH(P)-binding KR PF08659.5 KKK26876.1 - 4.2e-07 29.8 0.8 6.5e-07 29.1 0.6 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 KKK26876.1 - 0.0021 17.2 0.0 0.0027 16.8 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.16 KKK26876.1 - 0.02 14.3 0.5 0.032 13.6 0.4 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 KKK26876.1 - 0.032 13.1 0.1 0.055 12.3 0.1 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain ADH_zinc_N PF00107.21 KKK26876.1 - 0.13 11.8 0.4 0.25 10.9 0.3 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase MFS_1 PF07690.11 KKK26877.1 - 1.3e-42 145.7 55.8 1.6e-41 142.1 38.1 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily CHASE2 PF05226.6 KKK26877.1 - 0.12 11.5 0.8 0.23 10.6 0.5 1.4 1 0 0 1 1 1 0 CHASE2 domain FMN_red PF03358.10 KKK26878.1 - 2.4e-30 105.0 0.0 3e-30 104.7 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.12 KKK26878.1 - 2.3e-07 30.5 0.0 3.4e-07 29.9 0.0 1.3 1 1 0 1 1 1 1 Flavodoxin-like fold Fungal_trans PF04082.13 KKK26879.1 - 2.1e-10 39.9 0.0 6.2e-10 38.3 0.0 1.6 1 1 0 2 2 2 1 Fungal specific transcription factor domain K_trans PF02705.11 KKK26880.1 - 9.1e-179 595.2 18.9 1.1e-178 594.9 13.1 1.0 1 0 0 1 1 1 1 K+ potassium transporter PaaX PF07848.7 KKK26881.1 - 0.072 13.1 0.1 1.9 8.5 0.0 2.2 1 1 1 2 2 2 0 PaaX-like protein GntR PF00392.16 KKK26881.1 - 0.08 12.3 0.3 0.5 9.8 0.0 2.0 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family TauD PF02668.11 KKK26882.1 - 3.5e-24 85.8 0.0 4.8e-24 85.4 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF3439 PF11921.3 KKK26882.1 - 3.7 7.3 8.7 6 6.6 6.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) zf-C2H2 PF00096.21 KKK26883.1 - 0.0022 18.2 1.8 0.0044 17.2 1.2 1.5 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 KKK26883.1 - 0.004 17.2 3.4 0.0065 16.5 2.4 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KKK26883.1 - 0.0049 17.0 0.7 0.0081 16.3 0.5 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 KKK26883.1 - 0.012 15.8 0.6 0.025 14.8 0.4 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KKK26883.1 - 0.028 14.3 0.9 0.046 13.6 0.6 1.4 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_2 PF12756.2 KKK26883.1 - 0.035 14.2 0.4 0.056 13.5 0.3 1.2 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) UPF0240 PF06784.6 KKK26883.1 - 0.1 12.2 0.1 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0240) DUF1691 PF07950.6 KKK26884.1 - 8.3e-54 180.2 7.3 9.1e-36 122.1 2.6 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1691) Sdh_cyt PF01127.17 KKK26884.1 - 0.012 15.4 6.6 1.6 8.6 0.0 2.5 2 1 0 2 2 2 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Amidase PF01425.16 KKK26885.1 - 1.3e-114 383.4 0.2 1.6e-114 383.2 0.1 1.0 1 0 0 1 1 1 1 Amidase ADH_zinc_N PF00107.21 KKK26886.1 - 1.6e-11 43.8 0.0 3.2e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.20 KKK26886.1 - 0.0032 17.4 0.5 0.0054 16.6 0.4 1.3 1 0 0 1 1 1 1 short chain dehydrogenase ADH_N PF08240.7 KKK26886.1 - 0.0072 16.0 0.0 0.016 14.9 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain KR PF08659.5 KKK26886.1 - 0.019 14.6 0.3 0.033 13.8 0.2 1.3 1 0 0 1 1 1 0 KR domain DUF4265 PF14085.1 KKK26886.1 - 0.04 13.6 0.0 7.1 6.4 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4265) Metallophos PF00149.23 KKK26887.1 - 7.2e-09 35.3 5.6 7.8e-09 35.2 3.0 1.7 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Transket_pyr PF02779.19 KKK26888.1 - 1.3e-45 155.0 0.0 1.9e-45 154.5 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 KKK26888.1 - 1.9e-36 124.7 0.0 7.9e-36 122.7 0.0 2.0 2 0 0 2 2 2 1 Transketolase, C-terminal domain Snf7 PF03357.16 KKK26889.1 - 1.3e-05 24.6 7.9 1.6e-05 24.3 5.5 1.1 1 0 0 1 1 1 1 Snf7 DUF4157 PF13699.1 KKK26889.1 - 0.0048 17.0 4.7 0.0094 16.0 1.7 2.3 1 1 1 2 2 2 1 Domain of unknown function (DUF4157) ThiS PF02597.15 KKK26889.1 - 0.11 12.9 1.1 0.21 12.0 0.2 1.9 2 0 0 2 2 2 0 ThiS family Remorin_C PF03763.8 KKK26889.1 - 0.14 11.6 8.9 0.26 10.8 6.1 1.5 1 0 0 1 1 1 0 Remorin, C-terminal region bZIP_2 PF07716.10 KKK26890.1 - 5e-11 42.2 17.1 5e-11 42.2 11.9 2.5 1 1 1 2 2 2 2 Basic region leucine zipper bZIP_1 PF00170.16 KKK26890.1 - 1.6e-05 24.7 17.3 3.5e-05 23.6 12.0 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.12 KKK26890.1 - 0.00039 20.6 14.9 0.00082 19.6 10.3 1.5 1 0 0 1 1 1 1 bZIP Maf transcription factor Spc24 PF08286.6 KKK26890.1 - 0.024 14.3 1.2 0.057 13.1 0.8 1.6 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 APG6 PF04111.7 KKK26890.1 - 0.54 9.2 11.1 0.87 8.5 7.7 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Bystin PF05291.6 KKK26891.1 - 5.6e-128 426.1 0.0 7.6e-128 425.6 0.0 1.1 1 0 0 1 1 1 1 Bystin MFS_1 PF07690.11 KKK26893.1 - 1.5e-32 112.6 28.3 1.5e-32 112.6 19.6 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Ceramidase PF05875.7 KKK26893.1 - 0.89 8.6 8.5 0.13 11.4 1.8 2.3 2 1 1 3 3 3 0 Ceramidase HAD PF12710.2 KKK26894.1 - 1.7e-09 38.1 0.0 2.9e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.7 KKK26894.1 - 5.7e-06 25.6 0.0 0.039 13.1 0.0 2.1 2 0 0 2 2 2 2 Putative Phosphatase Hydrolase PF00702.21 KKK26894.1 - 0.018 15.4 0.1 0.32 11.3 0.0 2.2 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase MFS_1 PF07690.11 KKK26895.1 - 3.9e-25 88.3 26.1 2.8e-13 49.3 8.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KKK26895.1 - 2.2e-07 29.6 8.9 0.00026 19.5 0.1 2.7 2 1 0 2 2 2 2 MFS/sugar transport protein Sugar_tr PF00083.19 KKK26895.1 - 5.4e-06 25.2 8.6 8.5e-06 24.6 6.0 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter AA_permease_2 PF13520.1 KKK26897.1 - 2.5e-66 223.9 40.5 3.1e-66 223.6 28.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KKK26897.1 - 8.2e-24 83.7 35.7 1.1e-23 83.3 24.7 1.1 1 0 0 1 1 1 1 Amino acid permease p450 PF00067.17 KKK26898.1 - 1.4e-66 224.8 0.0 1.9e-66 224.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF2150 PF09920.4 KKK26898.1 - 0.097 12.2 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2150) Sigma70_ECF PF07638.6 KKK26899.1 - 0.026 14.2 3.3 0.055 13.1 2.3 1.5 1 0 0 1 1 1 0 ECF sigma factor DUF3824 PF12868.2 KKK26899.1 - 2.6 9.0 8.9 0.24 12.3 0.6 2.5 1 1 0 2 2 2 0 Domain of unknwon function (DUF3824) D-ser_dehydrat PF14031.1 KKK26900.1 - 4.5e-20 71.6 0.0 1.1e-19 70.3 0.0 1.7 1 0 0 1 1 1 1 Putative serine dehydratase domain Ala_racemase_N PF01168.15 KKK26900.1 - 8.9e-12 45.0 0.1 1.5e-11 44.2 0.1 1.4 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Fungal_trans PF04082.13 KKK26901.1 - 8.3e-08 31.4 0.5 2.2e-07 30.0 0.3 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Lzipper-MIP1 PF14389.1 KKK26901.1 - 0.031 14.3 1.1 0.15 12.2 0.4 2.2 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 DUF3596 PF12167.3 KKK26901.1 - 0.19 11.2 0.2 0.41 10.2 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3596) CoA_trans PF01144.18 KKK26902.1 - 5.9e-94 313.2 3.1 8.3e-59 198.3 0.1 2.1 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.1 KKK26902.1 - 0.02 14.5 1.2 0.025 14.2 0.0 1.7 2 0 0 2 2 2 0 Acetyl-CoA hydrolase/transferase C-terminal domain adh_short_C2 PF13561.1 KKK26903.1 - 2e-21 76.8 0.0 4.9e-20 72.3 0.0 2.5 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase ketoacyl-synt PF00109.21 KKK26903.1 - 2.2e-21 76.4 0.1 3.2e-20 72.7 0.0 2.4 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACPS PF01648.15 KKK26903.1 - 8.9e-19 67.4 0.0 1.9e-18 66.3 0.0 1.6 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Ketoacyl-synt_C PF02801.17 KKK26903.1 - 8e-12 45.0 0.0 2e-11 43.7 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.20 KKK26903.1 - 2.7e-06 27.3 0.0 7.7e-06 25.9 0.0 1.8 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KKK26903.1 - 0.0008 19.1 0.0 0.0023 17.5 0.0 1.8 1 0 0 1 1 1 1 KR domain TRM PF02005.11 KKK26904.1 - 1.6e-111 372.8 0.0 3.3e-97 325.7 0.0 2.1 2 0 0 2 2 2 2 N2,N2-dimethylguanosine tRNA methyltransferase Met_10 PF02475.11 KKK26904.1 - 0.0004 20.0 0.0 0.00071 19.2 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_3 PF01596.12 KKK26904.1 - 0.098 11.6 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase Pex14_N PF04695.8 KKK26904.1 - 0.26 11.3 6.5 2 8.4 0.2 3.2 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region TGF_beta_GS PF08515.7 KKK26905.1 - 2.2 7.7 5.3 4.1 6.8 3.7 1.4 1 0 0 1 1 1 0 Transforming growth factor beta type I GS-motif HMGL-like PF00682.14 KKK26906.1 - 1.3e-65 221.3 0.0 2.4e-65 220.5 0.0 1.4 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.5 KKK26906.1 - 1.9e-21 76.2 0.0 4.2e-21 75.1 0.0 1.6 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain DEAD PF00270.24 KKK26907.1 - 2.6e-44 150.7 1.5 7.5e-44 149.1 0.0 2.4 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KKK26907.1 - 1.4e-26 92.1 0.0 6.6e-26 89.9 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF1253 PF06862.7 KKK26907.1 - 5.2e-05 21.8 0.0 5.2e-05 21.8 0.0 2.9 2 1 2 4 4 4 1 Protein of unknown function (DUF1253) Ribosomal_S7 PF00177.16 KKK26908.1 - 1e-38 132.2 1.1 1.4e-38 131.8 0.8 1.2 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e AMP-binding PF00501.23 KKK26909.1 - 3.6e-59 200.2 0.3 9.4e-33 113.2 0.0 4.4 2 2 0 2 2 2 2 AMP-binding enzyme DUF4032 PF13224.1 KKK26909.1 - 0.21 11.2 0.1 18 5.0 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4032) RNR_inhib PF08591.5 KKK26910.1 - 4.7e-21 75.5 0.4 1.8e-20 73.6 0.0 2.2 2 1 0 2 2 2 1 Ribonucleotide reductase inhibitor SDA1 PF05285.7 KKK26911.1 - 6.7e-99 331.2 28.0 6.7e-99 331.2 19.4 2.1 2 0 0 2 2 2 2 SDA1 NUC130_3NT PF08158.7 KKK26911.1 - 6.8e-21 74.3 0.1 1.5e-20 73.1 0.1 1.7 1 0 0 1 1 1 1 NUC130/3NT domain Tho2 PF11262.3 KKK26911.1 - 0.45 9.5 0.0 0.45 9.5 0.0 2.6 3 0 0 3 3 3 0 Transcription factor/nuclear export subunit protein 2 Amidase PF01425.16 KKK26912.1 - 5.7e-80 269.3 0.1 1.7e-78 264.4 0.1 2.1 1 1 0 1 1 1 1 Amidase PDEase_II PF02112.10 KKK26913.1 - 7.2e-54 182.9 0.0 2.4e-45 154.9 0.0 2.7 2 1 0 2 2 2 2 cAMP phosphodiesterases class-II Lactamase_B_2 PF12706.2 KKK26913.1 - 0.00092 18.8 0.1 0.0042 16.6 0.0 1.9 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 KKK26913.1 - 0.0045 16.6 0.1 0.0084 15.7 0.1 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily ALO PF04030.9 KKK26914.1 - 3e-89 299.0 0.3 3.9e-89 298.6 0.2 1.1 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.18 KKK26914.1 - 2.2e-34 117.9 0.4 3.2e-34 117.3 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain DUF4045 PF13254.1 KKK26915.1 - 1.1e-148 495.9 29.9 1.1e-148 495.9 20.7 4.9 4 1 0 5 5 5 1 Domain of unknown function (DUF4045) Gelsolin PF00626.17 KKK26915.1 - 1.5e-11 43.7 0.0 2.7e-05 23.7 0.0 3.7 3 0 0 3 3 3 3 Gelsolin repeat Arf PF00025.16 KKK26916.1 - 8.8e-58 194.3 2.4 2.2e-56 189.8 0.2 2.0 2 0 0 2 2 2 2 ADP-ribosylation factor family Ras PF00071.17 KKK26916.1 - 3.1e-09 36.4 0.0 3.7e-09 36.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 KKK26916.1 - 7.9e-08 31.7 0.0 1e-07 31.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 KKK26916.1 - 4e-07 29.0 2.3 5.7e-06 25.2 0.1 2.7 2 1 1 3 3 3 1 G-protein alpha subunit MMR_HSR1 PF01926.18 KKK26916.1 - 8e-07 29.0 0.0 1.2e-06 28.4 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KKK26916.1 - 1.7e-06 28.5 0.0 2.4e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 KKK26916.1 - 2.4e-06 27.1 0.0 4.3e-05 23.0 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 KKK26916.1 - 3.7e-05 23.0 0.0 5.1e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit HCV_NS1 PF01560.12 KKK26916.1 - 0.035 12.5 0.0 0.04 12.3 0.0 1.1 1 0 0 1 1 1 0 Hepatitis C virus non-structural protein E2/NS1 AAA_17 PF13207.1 KKK26916.1 - 0.081 13.7 0.0 0.13 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain Acetyltransf_1 PF00583.19 KKK26917.1 - 0.00096 19.1 0.0 0.0021 18.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 KKK26917.1 - 0.0011 18.8 0.0 0.004 17.1 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KKK26917.1 - 0.0075 16.3 0.0 0.022 14.9 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain SPRY PF00622.23 KKK26918.1 - 1.1e-20 74.0 0.2 2.3e-20 72.9 0.0 1.7 2 0 0 2 2 2 1 SPRY domain Peptidase_M24 PF00557.19 KKK26919.1 - 1e-59 201.6 0.1 1.3e-59 201.2 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 KKK26919.1 - 3e-25 88.1 0.0 6.1e-25 87.1 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain KapB PF08810.5 KKK26919.1 - 0.06 13.4 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Kinase associated protein B Sec63 PF02889.11 KKK26920.1 - 6.9e-50 170.0 0.0 2.4e-48 164.9 0.0 2.1 1 1 0 1 1 1 1 Sec63 Brl domain DnaJ PF00226.26 KKK26920.1 - 9.8e-18 63.6 0.7 2.3e-17 62.4 0.5 1.7 1 0 0 1 1 1 1 DnaJ domain 7tm_1 PF00001.16 KKK26920.1 - 0.047 12.8 0.1 0.094 11.8 0.0 1.4 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) UPF0104 PF03706.8 KKK26920.1 - 0.13 11.5 1.8 0.11 11.7 0.1 1.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0104) Zn_clus PF00172.13 KKK26921.1 - 1.9e-08 34.0 14.3 4e-08 33.0 9.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Multi-haem_cyto PF13447.1 KKK26921.1 - 0.01 14.9 1.5 0.017 14.1 1.0 1.3 1 0 0 1 1 1 0 Seven times multi-haem cytochrome CxxCH DUF3402 PF11882.3 KKK26922.1 - 6.8e-167 555.6 0.0 8.8e-167 555.2 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3402) N1221 PF07923.8 KKK26922.1 - 8.4e-103 343.2 0.0 1.2e-102 342.7 0.0 1.2 1 0 0 1 1 1 1 N1221-like protein PAP2 PF01569.16 KKK26923.1 - 4.2e-15 55.5 2.2 4.2e-15 55.5 1.5 2.0 1 1 1 2 2 2 1 PAP2 superfamily DUF212 PF02681.9 KKK26923.1 - 0.0079 15.9 0.0 0.31 10.7 0.0 2.2 2 0 0 2 2 2 1 Divergent PAP2 family Dpy-30 PF05186.8 KKK26923.1 - 0.6 9.6 2.9 1.9 8.0 0.3 2.4 2 0 0 2 2 2 0 Dpy-30 motif DUF4131 PF13567.1 KKK26923.1 - 4.8 6.5 8.6 9.7 5.5 3.8 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) Elong_Iki1 PF10483.4 KKK26924.1 - 3.7e-94 315.2 0.0 4.3e-94 315.0 0.0 1.0 1 0 0 1 1 1 1 Elongator subunit Iki1 E1-E2_ATPase PF00122.15 KKK26925.1 - 1.3e-17 63.5 0.0 7.2e-17 61.1 0.0 2.2 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 KKK26925.1 - 8.6e-15 55.7 0.1 6e-14 52.9 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KKK26925.1 - 1e-09 38.8 0.3 2.5e-09 37.6 0.2 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KKK26925.1 - 7.3e-06 25.8 0.0 3.1e-05 23.8 0.0 2.1 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KKK26925.1 - 0.0046 16.5 0.0 0.01 15.4 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Mso1_Sec1_bdg PF14475.1 KKK26926.1 - 2.6e-10 39.5 0.0 4.5e-10 38.7 0.0 1.4 1 0 0 1 1 1 1 Sec1-binding region of Mso1 FAM220 PF15487.1 KKK26926.1 - 0.07 12.4 2.8 0.12 11.7 2.0 1.5 1 1 0 1 1 1 0 FAM220 family Ribosomal_L28e PF01778.12 KKK26927.1 - 1.3e-31 109.4 0.2 2.3e-31 108.6 0.1 1.4 1 0 0 1 1 1 1 Ribosomal L28e protein family Mak16 PF04874.9 KKK26927.1 - 1.2e-23 83.1 12.2 1.2e-23 83.1 8.4 2.5 2 0 0 2 2 2 1 Mak16 protein C-terminal region BUD22 PF09073.5 KKK26927.1 - 6.7e-07 28.7 14.6 9.2e-07 28.2 10.1 1.2 1 0 0 1 1 1 1 BUD22 TFIIF_alpha PF05793.7 KKK26927.1 - 0.00062 18.2 22.7 0.00075 17.9 15.7 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Nop14 PF04147.7 KKK26927.1 - 0.081 10.8 27.1 0.11 10.3 18.8 1.1 1 0 0 1 1 1 0 Nop14-like family ASXH PF13919.1 KKK26928.1 - 4e-20 72.0 6.8 1.1e-14 54.3 0.1 2.3 1 1 1 2 2 2 2 Asx homology domain AT_hook PF02178.14 KKK26928.1 - 9.2 6.3 13.1 0.91 9.4 4.4 2.7 2 0 0 2 2 2 0 AT hook motif Longin PF13774.1 KKK26929.1 - 3.8e-29 100.0 0.6 5.7e-29 99.4 0.4 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 KKK26929.1 - 4.4e-14 51.8 0.0 8.9e-14 50.8 0.0 1.5 1 0 0 1 1 1 1 Synaptobrevin PilJ PF13675.1 KKK26929.1 - 1.1 9.5 4.6 1.2 9.4 0.4 2.1 2 0 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term RWD PF05773.17 KKK26930.1 - 2.1e-23 82.3 0.0 3.5e-23 81.6 0.0 1.4 1 0 0 1 1 1 1 RWD domain IBR PF01485.16 KKK26930.1 - 9.7e-19 67.0 37.5 1.4e-13 50.5 2.7 4.0 3 1 1 4 4 4 2 IBR domain zf-RING_2 PF13639.1 KKK26930.1 - 0.0035 17.1 11.4 0.0035 17.1 7.9 3.7 2 1 1 3 3 3 1 Ring finger domain PEP-utilizers PF00391.18 KKK26931.1 - 0.088 12.3 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 PEP-utilising enzyme, mobile domain Fungal_trans PF04082.13 KKK26932.1 - 6.5e-25 87.4 0.1 1.2e-24 86.6 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK26932.1 - 1e-05 25.3 14.2 2.6e-05 24.0 9.9 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain N2227 PF07942.7 KKK26933.1 - 9.7e-91 303.4 0.0 1.2e-90 303.1 0.0 1.1 1 0 0 1 1 1 1 N2227-like protein Methyltransf_23 PF13489.1 KKK26933.1 - 0.00034 20.3 0.0 0.00058 19.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KKK26933.1 - 0.041 14.3 0.0 0.19 12.2 0.0 2.2 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.7 KKK26933.1 - 0.05 14.0 0.0 0.12 12.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain AAA_2 PF07724.9 KKK26935.1 - 7.8e-46 156.1 0.0 2.1e-44 151.4 0.0 2.8 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 KKK26935.1 - 1.3e-27 96.5 0.0 1.8e-15 57.3 0.0 3.1 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 KKK26935.1 - 1.5e-24 85.6 0.4 5.2e-24 83.9 0.3 2.0 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_16 PF13191.1 KKK26935.1 - 8.3e-16 58.5 14.5 6.6e-06 26.2 0.0 5.8 4 3 2 6 6 5 3 AAA ATPase domain AAA_5 PF07728.9 KKK26935.1 - 1.5e-15 57.1 0.0 1.1e-09 38.1 0.0 3.2 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KKK26935.1 - 2.7e-15 56.6 0.0 1.7e-05 24.9 0.0 4.1 2 1 1 3 3 3 2 AAA domain AAA_17 PF13207.1 KKK26935.1 - 9.3e-09 36.1 2.7 0.0082 16.9 0.0 3.9 2 2 0 2 2 2 2 AAA domain Sigma54_activat PF00158.21 KKK26935.1 - 1.7e-08 34.1 0.0 2.6e-05 23.7 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain Clp_N PF02861.15 KKK26935.1 - 7.9e-08 32.1 0.7 0.00034 20.4 0.0 4.3 3 0 0 3 3 3 1 Clp amino terminal domain IstB_IS21 PF01695.12 KKK26935.1 - 1.2e-07 31.2 0.0 0.021 14.2 0.0 2.9 3 0 0 3 3 2 2 IstB-like ATP binding protein AAA_14 PF13173.1 KKK26935.1 - 1.9e-07 31.0 0.0 0.019 14.8 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA_18 PF13238.1 KKK26935.1 - 9.1e-07 29.2 2.9 0.026 14.8 0.0 4.0 4 0 0 4 4 3 2 AAA domain AAA_19 PF13245.1 KKK26935.1 - 1e-06 28.4 2.4 0.018 14.7 0.0 3.2 3 0 0 3 3 2 2 Part of AAA domain Mg_chelatase PF01078.16 KKK26935.1 - 5.4e-06 25.7 0.5 0.15 11.1 0.0 4.2 3 1 0 4 4 4 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 KKK26935.1 - 4.6e-05 23.5 0.0 0.42 10.8 0.0 2.7 2 0 0 2 2 2 2 RNA helicase AAA_33 PF13671.1 KKK26935.1 - 6.2e-05 22.9 0.0 0.22 11.4 0.0 3.4 3 0 0 3 3 2 2 AAA domain AAA_28 PF13521.1 KKK26935.1 - 7.2e-05 22.8 2.7 0.31 10.9 0.0 3.7 3 1 1 4 4 3 2 AAA domain MobB PF03205.9 KKK26935.1 - 0.00013 21.6 0.0 0.77 9.4 0.0 2.6 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B T2SE PF00437.15 KKK26935.1 - 0.00014 20.8 0.0 0.0071 15.2 0.0 2.5 2 0 0 2 2 2 1 Type II/IV secretion system protein Arch_ATPase PF01637.13 KKK26935.1 - 0.0002 21.1 14.8 0.013 15.1 0.3 5.3 5 2 0 6 6 4 2 Archaeal ATPase AAA_25 PF13481.1 KKK26935.1 - 0.00025 20.5 0.3 1.7 7.9 0.0 3.9 3 1 1 4 4 3 2 AAA domain AAA_3 PF07726.6 KKK26935.1 - 0.00039 20.0 0.0 1.3 8.5 0.0 3.3 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.22 KKK26935.1 - 0.00041 20.6 3.8 0.55 10.5 0.0 3.8 4 0 0 4 4 3 1 ABC transporter AAA_29 PF13555.1 KKK26935.1 - 0.00063 19.2 0.0 0.48 9.9 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF258 PF03193.11 KKK26935.1 - 0.0009 18.4 0.0 0.42 9.7 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function, DUF258 ResIII PF04851.10 KKK26935.1 - 0.0017 18.2 1.6 0.47 10.2 0.0 4.0 3 1 1 4 4 4 1 Type III restriction enzyme, res subunit AAA_10 PF12846.2 KKK26935.1 - 0.0027 17.1 5.3 1.2 8.5 0.0 4.7 4 2 1 6 6 6 1 AAA-like domain AAA_24 PF13479.1 KKK26935.1 - 0.0028 17.2 0.0 1.7 8.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.10 KKK26935.1 - 0.0032 17.1 0.0 0.23 11.1 0.0 3.2 3 0 0 3 3 3 1 NTPase NACHT PF05729.7 KKK26935.1 - 0.0053 16.4 0.0 0.43 10.2 0.0 2.6 2 0 0 2 2 2 1 NACHT domain AAA_21 PF13304.1 KKK26935.1 - 0.0084 16.1 0.0 1.9 8.3 0.0 3.0 3 0 0 3 3 2 1 AAA domain Torsin PF06309.6 KKK26935.1 - 0.023 14.5 0.0 0.08 12.8 0.0 1.8 2 0 0 2 2 1 0 Torsin SRP54 PF00448.17 KKK26935.1 - 0.025 14.0 0.0 6.8 6.0 0.0 2.8 3 0 0 3 3 2 0 SRP54-type protein, GTPase domain UPF0079 PF02367.12 KKK26935.1 - 0.044 13.4 0.0 11 5.6 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 MMR_HSR1 PF01926.18 KKK26935.1 - 0.081 12.8 0.0 2.1 8.3 0.0 3.3 3 0 0 3 3 3 0 50S ribosome-binding GTPase ATP_bind_1 PF03029.12 KKK26935.1 - 0.1 12.1 0.0 21 4.5 0.0 2.9 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein Caldesmon PF02029.10 KKK26935.1 - 0.17 10.2 16.7 0.14 10.5 9.4 2.0 2 0 0 2 2 2 0 Caldesmon Viral_P18 PF04521.8 KKK26935.1 - 1.3 8.4 6.4 3 7.3 0.3 2.6 2 0 0 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein Occludin_ELL PF07303.8 KKK26935.1 - 1.5 9.5 12.0 0.5 11.1 5.3 2.4 2 0 0 2 2 1 0 Occludin homology domain V_ATPase_I PF01496.14 KKK26935.1 - 2.3 5.9 4.4 4.3 5.0 3.0 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family IncA PF04156.9 KKK26935.1 - 2.9 7.4 9.5 9.7 5.7 6.6 1.9 1 0 0 1 1 1 0 IncA protein Prefoldin_2 PF01920.15 KKK26936.1 - 1.6e-23 82.5 4.2 2e-23 82.1 2.9 1.1 1 0 0 1 1 1 1 Prefoldin subunit ALIX_LYPXL_bnd PF13949.1 KKK26936.1 - 0.0011 18.0 3.2 0.0013 17.7 2.2 1.1 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV Prefoldin PF02996.12 KKK26936.1 - 0.0087 15.7 5.1 0.012 15.2 0.3 2.1 1 1 1 2 2 2 1 Prefoldin subunit Med30 PF11315.3 KKK26936.1 - 0.0091 16.1 1.3 0.012 15.6 0.9 1.2 1 0 0 1 1 1 1 Mediator complex subunit 30 Nnf1 PF03980.9 KKK26936.1 - 0.016 15.1 4.1 0.024 14.6 2.9 1.4 1 0 0 1 1 1 0 Nnf1 Spc24 PF08286.6 KKK26936.1 - 0.13 11.9 4.4 2.2 7.9 1.3 2.2 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 CENP-F_leu_zip PF10473.4 KKK26936.1 - 0.24 11.2 13.2 1.4 8.7 0.1 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 SPX PF03105.14 KKK26936.1 - 0.26 11.0 2.5 0.35 10.6 1.7 1.1 1 0 0 1 1 1 0 SPX domain PEP-utilisers_N PF05524.8 KKK26936.1 - 0.29 10.9 3.4 0.49 10.1 0.0 2.1 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal TBCA PF02970.11 KKK26936.1 - 0.31 11.1 9.2 0.48 10.5 3.2 2.1 1 1 1 2 2 2 0 Tubulin binding cofactor A Fib_alpha PF08702.5 KKK26936.1 - 0.8 9.8 4.0 9.5 6.3 2.8 2.0 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF4200 PF13863.1 KKK26936.1 - 0.93 9.4 12.3 3.9 7.4 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) DivIC PF04977.10 KKK26936.1 - 1 8.9 11.6 5.3 6.6 0.3 2.3 2 0 0 2 2 2 0 Septum formation initiator CENP-H PF05837.7 KKK26936.1 - 1.2 9.3 6.6 17 5.6 0.0 2.1 2 0 0 2 2 2 0 Centromere protein H (CENP-H) ADIP PF11559.3 KKK26936.1 - 2.8 7.8 8.6 9.9 6.0 0.0 2.1 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding IncA PF04156.9 KKK26936.1 - 3.1 7.3 13.4 7.1 6.1 9.3 1.6 1 1 0 1 1 1 0 IncA protein DUF1843 PF08898.5 KKK26936.1 - 5.2 7.1 7.0 3.1 7.9 0.2 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF1843) Spc7 PF08317.6 KKK26936.1 - 5.9 5.4 9.3 15 4.1 6.4 1.6 1 1 0 1 1 1 0 Spc7 kinetochore protein ATG27 PF09451.5 KKK26937.1 - 3.6e-84 282.1 0.0 4.2e-84 281.9 0.0 1.0 1 0 0 1 1 1 1 Autophagy-related protein 27 CIMR PF00878.13 KKK26937.1 - 8.4e-07 28.8 0.0 3.7e-05 23.5 0.0 2.5 3 0 0 3 3 3 1 Cation-independent mannose-6-phosphate receptor repeat Tubulin_3 PF14881.1 KKK26938.1 - 2.9e-84 281.0 0.0 4.3e-84 280.4 0.0 1.3 1 0 0 1 1 1 1 Tubulin domain Misat_Tub_SegII PF10644.4 KKK26938.1 - 5e-41 139.3 0.0 2.3e-40 137.2 0.0 2.2 3 0 0 3 3 3 1 Misato Segment II tubulin-like domain Tubulin PF00091.20 KKK26938.1 - 0.00076 19.3 0.0 1.5 8.6 0.0 2.3 2 0 0 2 2 2 2 Tubulin/FtsZ family, GTPase domain DUF1098 PF06497.6 KKK26938.1 - 0.02 14.9 0.2 2.8 8.0 0.0 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1098) HSP70 PF00012.15 KKK26940.1 - 1.5e-60 204.7 2.9 3.6e-58 196.9 0.0 3.2 3 0 0 3 3 3 2 Hsp70 protein SlyX PF04102.7 KKK26940.1 - 1.6 9.1 7.1 0.41 11.0 0.3 3.4 2 1 1 3 3 3 0 SlyX SNF2_N PF00176.18 KKK26942.1 - 3.6e-64 216.4 0.0 5.3e-64 215.8 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KKK26942.1 - 8.6e-12 44.7 0.0 3.9e-11 42.6 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KKK26942.1 - 0.00024 21.0 0.2 0.00084 19.2 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Ribosomal_60s PF00428.14 KKK26942.1 - 0.27 11.6 4.5 0.84 10.0 3.1 1.8 1 0 0 1 1 1 0 60s Acidic ribosomal protein DUF2347 PF09804.4 KKK26943.1 - 6.3e-106 353.7 0.0 1.1e-105 352.9 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) DUF4484 PF14831.1 KKK26943.1 - 6.5e-64 215.2 1.3 7.3e-64 215.0 0.1 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4484) Avl9 PF09794.4 KKK26943.1 - 0.0024 16.3 0.0 1.4 7.3 0.0 2.4 2 1 0 2 2 2 2 Transport protein Avl9 SPA PF08616.5 KKK26943.1 - 0.067 12.9 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Stabilization of polarity axis DUF1523 PF07509.6 KKK26943.1 - 0.13 11.4 0.1 0.23 10.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1523) EBP PF05241.7 KKK26944.1 - 2.3e-52 176.8 6.4 2.6e-52 176.6 4.4 1.0 1 0 0 1 1 1 1 Emopamil binding protein YMF19 PF02326.10 KKK26944.1 - 0.23 12.0 3.3 3 8.4 0.1 2.2 2 0 0 2 2 2 0 Plant ATP synthase F0 AA_permease_2 PF13520.1 KKK26945.1 - 3.7e-40 137.7 49.1 4.5e-40 137.4 34.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KKK26945.1 - 7.9e-22 77.2 39.9 1.1e-21 76.7 27.6 1.0 1 0 0 1 1 1 1 Amino acid permease TMEM173 PF15009.1 KKK26945.1 - 0.032 13.0 0.3 0.086 11.6 0.0 1.8 2 0 0 2 2 2 0 Transmembrane protein 173 DASH_Dad1 PF08649.5 KKK26947.1 - 1e-22 79.5 2.1 1.4e-22 79.1 1.5 1.2 1 0 0 1 1 1 1 DASH complex subunit Dad1 Occludin_ELL PF07303.8 KKK26947.1 - 0.092 13.4 0.0 0.12 13.0 0.0 1.2 1 0 0 1 1 1 0 Occludin homology domain ERG4_ERG24 PF01222.12 KKK26948.1 - 3.5e-134 447.5 18.1 4.1e-134 447.3 12.5 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Fungal_trans PF04082.13 KKK26949.1 - 3.9e-19 68.5 0.1 3.9e-19 68.5 0.1 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK26949.1 - 9e-09 35.1 6.8 1.6e-08 34.2 4.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_M16_C PF05193.16 KKK26949.1 - 0.11 12.1 0.0 0.48 10.0 0.0 2.0 2 0 0 2 2 2 0 Peptidase M16 inactive domain DUF3712 PF12505.3 KKK26950.1 - 1.3e-31 109.2 0.1 4.1e-31 107.5 0.1 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3712) YlbD_coat PF14071.1 KKK26950.1 - 8.5 6.4 6.7 20 5.2 0.1 4.0 3 2 2 5 5 5 0 Putative coat protein UPRTase PF14681.1 KKK26951.1 - 0.15 11.2 0.0 0.31 10.2 0.0 1.4 2 0 0 2 2 2 0 Uracil phosphoribosyltransferase MFS_1 PF07690.11 KKK26953.1 - 9.2e-45 152.8 43.9 1.2e-44 152.4 30.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KKK26953.1 - 4.6e-10 38.6 23.1 8.8e-10 37.7 16.0 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter AMP-binding PF00501.23 KKK26953.1 - 6.9e-10 37.8 0.1 1.1e-09 37.1 0.1 1.3 1 0 0 1 1 1 1 AMP-binding enzyme TRI12 PF06609.8 KKK26953.1 - 5.5e-06 24.8 4.1 8.7e-06 24.2 2.9 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) AMP-binding_C PF13193.1 KKK26953.1 - 0.00017 22.4 0.6 0.00083 20.2 0.4 2.2 1 1 0 1 1 1 1 AMP-binding enzyme C-terminal domain OATP PF03137.15 KKK26953.1 - 0.00066 17.8 7.7 0.36 8.8 0.7 3.7 4 0 0 4 4 4 3 Organic Anion Transporter Polypeptide (OATP) family RTA1 PF04479.8 KKK26954.1 - 6.2e-44 150.1 4.1 8.8e-44 149.6 2.9 1.1 1 0 0 1 1 1 1 RTA1 like protein Zn_clus PF00172.13 KKK26955.1 - 2.5e-08 33.6 10.6 6.4e-08 32.3 7.3 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2 PF00096.21 KKK26955.1 - 0.0025 18.0 3.3 0.013 15.7 2.3 2.4 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KKK26955.1 - 0.0066 16.7 2.0 0.0066 16.7 1.4 2.7 3 0 0 3 3 3 1 C2H2-type zinc finger Condensation PF00668.15 KKK26956.1 - 1.7e-05 23.7 0.1 0.00018 20.4 0.1 2.2 1 1 0 1 1 1 1 Condensation domain ParG PF09274.5 KKK26956.1 - 0.15 11.9 0.0 0.38 10.6 0.0 1.6 1 0 0 1 1 1 0 ParG Ank_2 PF12796.2 KKK26957.1 - 3e-50 168.4 3.9 6.1e-18 64.9 0.2 8.0 4 2 3 8 8 8 8 Ankyrin repeats (3 copies) Ank PF00023.25 KKK26957.1 - 2.9e-35 118.3 13.5 3.5e-06 26.5 0.0 11.6 13 0 0 13 13 13 6 Ankyrin repeat Ank_5 PF13857.1 KKK26957.1 - 2.1e-34 116.7 13.8 1.3e-05 25.2 0.1 10.8 10 1 1 11 11 11 6 Ankyrin repeats (many copies) Ank_4 PF13637.1 KKK26957.1 - 7.1e-33 112.4 14.0 3e-08 33.9 0.0 10.7 9 2 2 11 11 11 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 KKK26957.1 - 9.7e-33 108.9 7.0 0.0012 18.8 0.0 12.2 13 0 0 13 13 13 5 Ankyrin repeat Mpv17_PMP22 PF04117.7 KKK26958.1 - 5.5e-19 67.5 0.4 5.5e-19 67.5 0.3 1.8 2 0 0 2 2 2 1 Mpv17 / PMP22 family MFS_1 PF07690.11 KKK26959.1 - 2.4e-37 128.4 48.2 2.4e-37 128.4 33.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KKK26959.1 - 5.7e-10 38.3 10.3 5.7e-10 38.3 7.1 2.3 1 1 0 2 2 2 1 Sugar (and other) transporter FTA4 PF13093.1 KKK26959.1 - 0.14 11.5 0.3 0.21 10.9 0.2 1.1 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 DUF2178 PF09946.4 KKK26959.1 - 3.3 7.5 6.9 0.46 10.2 0.2 2.8 3 0 0 3 3 3 0 Predicted membrane protein (DUF2178) Ribosomal_L29 PF00831.18 KKK26960.1 - 7.8e-20 70.3 0.3 1.9e-19 69.1 0.2 1.6 1 0 0 1 1 1 1 Ribosomal L29 protein IncA PF04156.9 KKK26960.1 - 0.03 13.9 1.7 0.038 13.5 1.2 1.2 1 0 0 1 1 1 0 IncA protein DUF3585 PF12130.3 KKK26960.1 - 0.11 12.3 4.4 0.17 11.7 3.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3585) Cortex-I_coil PF09304.5 KKK26960.1 - 0.34 10.9 7.6 0.064 13.3 1.7 2.0 1 1 1 2 2 2 0 Cortexillin I, coiled coil FliT PF05400.8 KKK26960.1 - 1.7 9.1 5.2 16 5.9 0.2 2.4 2 0 0 2 2 2 0 Flagellar protein FliT Med16 PF11635.3 KKK26961.1 - 1.2e-197 658.4 0.0 3.9e-102 342.5 0.0 2.1 1 1 1 2 2 2 2 Mediator complex subunit 16 Hydrolase_like PF13242.1 KKK26962.1 - 2.8e-08 33.3 0.0 5.1e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 KKK26962.1 - 1.8e-06 28.5 0.0 0.0058 17.0 0.0 2.1 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 KKK26962.1 - 2.5e-06 27.8 0.0 0.00021 21.5 0.0 2.1 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase SIR2 PF02146.12 KKK26963.1 - 3.3e-24 85.5 0.2 3.2e-23 82.3 0.0 2.5 2 1 0 2 2 2 1 Sir2 family Zn-ribbon_8 PF09723.5 KKK26963.1 - 0.09 12.7 2.3 0.37 10.7 1.0 2.4 2 0 0 2 2 2 0 Zinc ribbon domain VASP_tetra PF08776.6 KKK26964.1 - 0.16 11.3 0.8 0.41 9.9 0.5 1.7 1 0 0 1 1 1 0 VASP tetramerisation domain GN3L_Grn1 PF08701.6 KKK26965.1 - 2.1e-24 85.2 16.8 2.1e-24 85.2 11.7 2.3 3 0 0 3 3 1 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.18 KKK26965.1 - 4.1e-22 78.3 0.2 1.1e-15 57.6 0.0 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KKK26965.1 - 2e-06 27.3 0.0 0.087 12.2 0.0 2.7 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 KKK26965.1 - 4.1e-06 26.7 4.1 0.33 10.7 0.0 3.9 3 2 2 5 5 5 3 Dynamin family FeoB_N PF02421.13 KKK26965.1 - 1.3e-05 24.5 0.1 0.00011 21.5 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B DUF258 PF03193.11 KKK26965.1 - 0.0011 18.2 0.2 0.0018 17.4 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Miro PF08477.8 KKK26965.1 - 0.0024 18.3 1.6 0.2 12.1 0.0 2.7 3 0 0 3 3 2 1 Miro-like protein AIG1 PF04548.11 KKK26965.1 - 0.0067 15.5 0.5 0.5 9.4 0.0 2.9 3 0 0 3 3 3 1 AIG1 family Daxx PF03344.10 KKK26965.1 - 0.018 13.5 22.6 0.026 13.0 15.7 1.3 1 0 0 1 1 1 0 Daxx Family ArgK PF03308.11 KKK26965.1 - 0.036 12.8 0.1 0.036 12.8 0.0 2.0 2 0 0 2 2 2 0 ArgK protein ORC3_N PF07034.6 KKK26965.1 - 0.036 13.0 0.0 0.064 12.2 0.0 1.3 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 3 N-terminus AAA_18 PF13238.1 KKK26965.1 - 0.051 13.8 4.9 0.19 12.0 0.0 2.8 3 0 0 3 3 3 0 AAA domain cobW PF02492.14 KKK26965.1 - 0.085 12.3 0.0 1.2 8.5 0.0 2.4 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Nop14 PF04147.7 KKK26965.1 - 0.74 7.6 36.7 1.2 6.9 25.4 1.2 1 0 0 1 1 1 0 Nop14-like family CBFD_NFYB_HMF PF00808.18 KKK26966.1 - 0.00029 20.8 0.0 0.00052 20.0 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Pilt PF15453.1 KKK26966.1 - 0.022 14.4 13.8 0.03 14.0 9.6 1.2 1 0 0 1 1 1 0 Protein incorporated later into Tight Junctions TATR PF03430.8 KKK26966.1 - 0.37 9.3 8.3 0.42 9.2 5.7 1.1 1 0 0 1 1 1 0 Trans-activating transcriptional regulator DUF913 PF06025.7 KKK26966.1 - 7.7 5.1 5.8 11 4.5 4.0 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) adh_short PF00106.20 KKK26967.1 - 4.5e-13 49.4 0.0 4.9e-13 49.3 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KKK26967.1 - 2e-06 27.5 0.0 2.2e-06 27.4 0.0 1.0 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 KKK26967.1 - 0.025 13.4 0.0 0.027 13.3 0.0 1.0 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Methyltransf_2 PF00891.13 KKK26968.1 - 8e-31 107.0 0.1 1.1e-30 106.6 0.1 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 KKK26968.1 - 0.00021 21.8 0.0 0.00049 20.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KKK26968.1 - 0.00028 20.5 0.0 0.00052 19.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain HTH_AsnC-type PF13404.1 KKK26968.1 - 0.00069 19.0 0.0 0.0015 18.0 0.0 1.5 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain MTS PF05175.9 KKK26968.1 - 0.0017 17.7 0.0 0.0041 16.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.7 KKK26968.1 - 0.058 13.8 0.0 0.12 12.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain HTH_28 PF13518.1 KKK26968.1 - 0.06 13.3 0.0 0.17 11.9 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_24 PF13412.1 KKK26968.1 - 0.061 12.7 0.0 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Phage_lysozyme PF00959.14 KKK26968.1 - 0.13 12.5 0.1 0.28 11.4 0.0 1.5 1 0 0 1 1 1 0 Phage lysozyme Pkinase PF00069.20 KKK26969.1 - 4.5e-40 137.4 0.8 1.1e-24 87.0 0.3 2.5 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KKK26969.1 - 2.4e-14 53.0 0.4 2e-10 40.1 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase YopE PF03545.8 KKK26969.1 - 0.061 13.2 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 Yersinia virulence determinant (YopE) RIO1 PF01163.17 KKK26969.1 - 0.065 12.5 0.0 0.19 11.0 0.0 1.8 1 0 0 1 1 1 0 RIO1 family DNA_binding_1 PF01035.15 KKK26970.1 - 1.7e-20 72.5 0.0 2.2e-20 72.1 0.0 1.1 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Lipid_DES PF08557.5 KKK26971.1 - 0.058 12.6 0.0 4.8 6.5 0.0 2.7 2 0 0 2 2 2 0 Sphingolipid Delta4-desaturase (DES) MIF4G PF02854.14 KKK26972.1 - 1.9e-24 86.2 0.2 4.6e-24 85.0 0.1 1.7 1 0 0 1 1 1 1 MIF4G domain MA3 PF02847.12 KKK26972.1 - 2.7e-17 62.4 0.1 1.1e-16 60.5 0.0 2.1 2 0 0 2 2 2 1 MA3 domain Not3 PF04065.10 KKK26973.1 - 4.1e-98 327.3 18.9 5.7e-98 326.8 13.1 1.2 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.13 KKK26973.1 - 7.2e-45 152.1 11.4 1.6e-44 151.0 7.9 1.6 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family DUF2373 PF10180.4 KKK26973.1 - 0.0073 15.8 3.4 0.018 14.5 2.4 1.7 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) Cep57_MT_bd PF06657.8 KKK26973.1 - 0.015 15.2 4.7 0.11 12.4 0.1 2.7 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 DUF1192 PF06698.6 KKK26973.1 - 0.037 13.8 1.9 0.16 11.7 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) Snapin_Pallidin PF14712.1 KKK26973.1 - 0.07 13.4 7.1 0.15 12.4 0.4 2.5 2 0 0 2 2 2 0 Snapin/Pallidin Syntaxin_2 PF14523.1 KKK26973.1 - 0.16 11.9 7.4 0.042 13.8 1.3 2.4 2 0 0 2 2 2 0 Syntaxin-like protein Cob_adeno_trans PF01923.13 KKK26973.1 - 1.2 8.8 4.4 1.1 9.0 0.5 2.1 1 1 1 2 2 2 0 Cobalamin adenosyltransferase Syntaxin PF00804.20 KKK26973.1 - 3.8 7.7 12.3 0.28 11.3 2.0 2.5 1 1 1 2 2 2 0 Syntaxin DUF904 PF06005.7 KKK26973.1 - 4.7 7.5 10.7 8.8 6.7 2.7 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF904) SlyX PF04102.7 KKK26973.1 - 9 6.7 10.2 2.5 8.5 0.5 4.0 3 1 1 4 4 4 0 SlyX Tyr_Deacylase PF02580.11 KKK26974.1 - 1.1e-38 132.5 0.0 1.6e-36 125.4 0.0 2.1 1 1 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase Pro_isomerase PF00160.16 KKK26975.1 - 2.3e-48 164.3 0.7 4.1e-48 163.5 0.5 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_11 PF13414.1 KKK26975.1 - 1e-10 41.1 4.3 3.6e-05 23.3 0.1 2.3 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 KKK26975.1 - 3.7e-07 29.5 4.6 3.2e-05 23.4 0.1 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 KKK26975.1 - 1.6e-06 27.4 4.6 1.1e-05 24.8 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 KKK26975.1 - 8.6e-06 25.6 3.2 3.3e-05 23.7 1.2 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 KKK26975.1 - 0.0013 19.1 0.9 0.0074 16.8 0.3 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 KKK26975.1 - 0.014 15.1 3.7 0.041 13.6 0.1 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.1 KKK26975.1 - 0.025 14.4 0.7 0.086 12.7 0.4 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 KKK26975.1 - 0.22 12.2 5.6 1 10.1 2.5 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 KKK26975.1 - 0.28 11.7 1.8 1.6 9.3 0.1 3.2 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_19 PF14559.1 KKK26975.1 - 0.5 10.7 4.8 1 9.7 2.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Gly_transf_sug PF04488.10 KKK26976.1 - 7.6e-20 71.2 0.1 1.3e-19 70.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.7 KKK26976.1 - 0.013 14.6 0.1 0.022 13.9 0.1 1.3 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein TcdA_TcdB PF12919.2 KKK26976.1 - 0.26 9.7 4.8 1.7 7.0 0.3 2.1 2 0 0 2 2 2 0 TcdA/TcdB catalytic glycosyltransferase domain Coatomer_E PF04733.9 KKK26978.1 - 2.6e-16 59.6 0.0 2.9e-16 59.5 0.0 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_12 PF13424.1 KKK26978.1 - 0.00086 19.1 0.8 0.0025 17.6 0.1 2.0 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 KKK26978.1 - 0.0032 17.8 0.3 0.53 10.8 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 KKK26978.1 - 0.0037 17.5 2.9 0.0044 17.3 0.7 2.0 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 KKK26978.1 - 0.011 16.4 1.4 0.011 16.4 1.0 2.3 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.1 KKK26978.1 - 0.028 14.6 0.3 0.15 12.3 0.0 2.3 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.1 KKK26978.1 - 0.043 13.7 0.3 0.46 10.5 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Apc3 PF12895.2 KKK26978.1 - 0.049 13.7 0.0 11 6.2 0.0 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_20 PF14561.1 KKK26978.1 - 0.051 13.7 2.2 0.11 12.6 0.4 2.1 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_4 PF07721.9 KKK26978.1 - 0.12 12.8 0.1 0.12 12.8 0.1 3.3 4 1 0 4 4 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 KKK26978.1 - 0.34 11.6 6.7 1.9 9.3 0.3 3.3 2 1 2 4 4 3 0 Tetratricopeptide repeat PI-PLC-X PF00388.14 KKK26979.1 - 3.6e-59 198.3 0.0 6.3e-59 197.5 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 KKK26979.1 - 4.5e-41 139.5 0.1 1.6e-39 134.5 0.1 2.4 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_like PF09279.6 KKK26979.1 - 6.9e-05 22.7 0.0 0.00025 20.9 0.0 2.0 2 0 0 2 2 2 1 Phosphoinositide-specific phospholipase C, efhand-like GDPD PF03009.12 KKK26979.1 - 0.0027 17.2 0.0 0.0077 15.7 0.0 1.7 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family EF-hand_1 PF00036.27 KKK26979.1 - 0.022 14.0 1.2 0.071 12.4 0.1 2.4 2 0 0 2 2 2 0 EF hand EF-hand_7 PF13499.1 KKK26979.1 - 0.18 11.9 2.2 0.95 9.6 1.6 2.1 1 1 0 1 1 1 0 EF-hand domain pair EF-hand_6 PF13405.1 KKK26979.1 - 0.31 11.0 2.8 2.2 8.4 0.1 2.8 2 0 0 2 2 2 0 EF-hand domain SAP25 PF15476.1 KKK26980.1 - 0.0099 15.4 0.0 0.016 14.7 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase complex subunit SAP25 FCH PF00611.18 KKK26980.1 - 0.12 12.5 0.2 0.21 11.7 0.1 1.3 1 0 0 1 1 1 0 Fes/CIP4, and EFC/F-BAR homology domain Y_phosphatase2 PF03162.8 KKK26981.1 - 5.6e-49 165.6 0.0 7.1e-49 165.3 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 KKK26981.1 - 1.3e-10 41.8 0.0 8.1e-10 39.1 0.0 1.9 1 1 1 2 2 2 1 Tyrosine phosphatase family DSPc PF00782.15 KKK26981.1 - 0.00061 19.3 0.0 0.00081 18.9 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KKK26981.1 - 0.0023 17.3 0.0 0.003 16.9 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 KKK26981.1 - 0.0042 17.1 0.0 0.0062 16.6 0.0 1.2 1 0 0 1 1 1 1 Inositol hexakisphosphate CDKN3 PF05706.7 KKK26981.1 - 0.068 12.6 0.1 0.11 11.9 0.1 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Peptidase_M24 PF00557.19 KKK26982.1 - 1.2e-46 158.8 0.1 1.6e-46 158.4 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 NST1 PF13945.1 KKK26982.1 - 0.051 13.6 2.8 0.081 12.9 2.0 1.3 1 0 0 1 1 1 0 Salt tolerance down-regulator FA_desaturase PF00487.19 KKK26983.1 - 1.6e-26 93.2 16.2 3e-26 92.4 11.2 1.4 1 1 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.5 KKK26983.1 - 4.8e-20 70.5 0.2 8.2e-20 69.7 0.1 1.4 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) Rad52_Rad22 PF04098.10 KKK26984.1 - 1.5e-59 200.1 0.0 2.2e-59 199.6 0.0 1.2 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein Aa_trans PF01490.13 KKK26985.1 - 1.5e-74 250.9 32.3 1.9e-74 250.6 22.4 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Motile_Sperm PF00635.21 KKK26986.1 - 1.5e-23 82.4 0.7 3.5e-23 81.3 0.4 1.6 1 1 1 2 2 2 1 MSP (Major sperm protein) domain DUF2077 PF09850.4 KKK26986.1 - 0.065 12.6 0.0 0.099 12.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2077) UBA PF00627.26 KKK26987.1 - 5.2e-06 26.1 0.5 1.1e-05 25.1 0.0 1.8 2 0 0 2 2 2 1 UBA/TS-N domain UBX PF00789.15 KKK26987.1 - 0.0067 16.4 0.3 0.1 12.6 0.0 2.7 2 2 0 2 2 2 1 UBX domain zf-C2H2_2 PF12756.2 KKK26987.1 - 0.034 14.2 0.3 0.076 13.1 0.2 1.6 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) GATA PF00320.22 KKK26987.1 - 0.037 13.3 0.0 0.062 12.6 0.0 1.4 1 0 0 1 1 1 0 GATA zinc finger DUF3595 PF12166.3 KKK26987.1 - 0.08 11.7 0.5 0.1 11.4 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3595) zf-C2H2 PF00096.21 KKK26987.1 - 0.11 12.8 0.9 0.19 12.1 0.7 1.4 1 0 0 1 1 1 0 Zinc finger, C2H2 type Crystallin PF00525.13 KKK26987.1 - 0.13 12.4 0.0 0.23 11.7 0.0 1.3 1 0 0 1 1 1 0 Alpha crystallin A chain, N terminal zf-C2H2_jaz PF12171.3 KKK26987.1 - 0.18 12.0 1.5 0.31 11.2 1.0 1.4 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding Ycf1 PF05758.7 KKK26987.1 - 0.55 7.8 9.9 0.59 7.7 6.8 1.2 1 0 0 1 1 1 0 Ycf1 CAF-1_p150 PF11600.3 KKK26987.1 - 1.7 7.9 39.6 2.3 7.5 27.4 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Rtf2 PF04641.7 KKK26987.1 - 2.4 7.3 21.8 3.5 6.7 15.1 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger Hex_IIIa PF02455.11 KKK26987.1 - 2.5 6.7 12.7 3.5 6.2 8.8 1.3 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) CpXC PF14353.1 KKK26987.1 - 3.7 7.5 11.7 45 4.0 8.1 2.2 1 1 0 1 1 1 0 CpXC protein DUF342 PF03961.8 KKK26987.1 - 5.3 5.3 15.4 7.7 4.8 10.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) SOBP PF15279.1 KKK26987.1 - 5.6 7.2 9.3 6.9 6.9 6.4 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein SAP PF02037.22 KKK26989.1 - 2.3e-08 33.3 0.4 4.3e-08 32.4 0.0 1.7 2 0 0 2 2 2 1 SAP domain FMN_dh PF01070.13 KKK26990.1 - 5e-112 374.2 0.0 6.1e-112 374.0 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 KKK26990.1 - 9e-19 67.0 0.0 1.9e-18 66.0 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 KKK26990.1 - 5.5e-05 22.2 0.0 9.3e-05 21.5 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase ThiG PF05690.9 KKK26990.1 - 0.003 16.6 0.0 0.27 10.2 0.0 2.2 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG IMPDH PF00478.20 KKK26990.1 - 0.0098 14.8 0.1 0.026 13.3 0.0 1.7 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.10 KKK26990.1 - 0.035 13.2 0.2 6.9 5.7 0.0 2.2 1 1 1 2 2 2 0 Nitronate monooxygenase TatD_DNase PF01026.16 KKK26991.1 - 8.7e-51 172.5 0.0 1e-50 172.3 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase Vfa1 PF08432.5 KKK26992.1 - 2.1e-65 220.1 19.0 2.4e-65 219.9 13.2 1.0 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 CENP-T PF15511.1 KKK26992.1 - 0.0006 19.1 7.7 0.00072 18.9 5.3 1.1 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T CDC45 PF02724.9 KKK26992.1 - 0.0027 15.8 16.6 0.0032 15.6 11.5 1.0 1 0 0 1 1 1 1 CDC45-like protein DDHD PF02862.12 KKK26992.1 - 0.18 11.6 5.4 0.21 11.3 3.8 1.2 1 0 0 1 1 1 0 DDHD domain RR_TM4-6 PF06459.7 KKK26992.1 - 0.22 11.3 14.7 0.28 11.0 10.2 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF3449 PF11931.3 KKK26992.1 - 0.22 10.9 12.8 0.36 10.3 8.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) Raftlin PF15250.1 KKK26992.1 - 0.27 9.6 6.6 0.33 9.4 4.6 1.1 1 0 0 1 1 1 0 Raftlin Ycf1 PF05758.7 KKK26992.1 - 0.3 8.7 12.9 0.33 8.6 9.0 1.0 1 0 0 1 1 1 0 Ycf1 GAGA_bind PF06217.7 KKK26992.1 - 0.51 10.2 10.2 0.61 10.0 7.1 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family HCMV_UL139 PF12507.3 KKK26992.1 - 0.71 10.0 10.7 1.6 8.9 7.3 1.7 1 1 0 1 1 1 0 Human Cytomegalovirus UL139 protein GCD14 PF08704.5 KKK26992.1 - 0.73 9.2 5.3 0.98 8.8 3.7 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit DUF2201_N PF13203.1 KKK26992.1 - 0.8 8.8 7.1 0.93 8.6 4.9 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain DUF2252 PF10009.4 KKK26992.1 - 1.3 7.8 9.7 1.7 7.4 6.7 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) Hid1 PF12722.2 KKK26992.1 - 1.5 6.4 10.7 1.7 6.2 7.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein UPF0560 PF10577.4 KKK26992.1 - 1.5 6.9 8.5 1.8 6.7 5.9 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 NPR3 PF03666.8 KKK26992.1 - 1.6 7.1 11.8 2 6.8 8.2 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF1510 PF07423.6 KKK26992.1 - 2 7.7 24.3 2.7 7.3 16.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) NARP1 PF12569.3 KKK26992.1 - 2.1 7.0 17.7 2.6 6.7 12.3 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 PBP_sp32 PF07222.7 KKK26992.1 - 2.3 7.3 10.1 2.9 6.9 7.0 1.2 1 0 0 1 1 1 0 Proacrosin binding protein sp32 MIP-T3 PF10243.4 KKK26992.1 - 2.8 6.3 26.6 3.3 6.0 18.4 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 FAM60A PF15396.1 KKK26992.1 - 4.8 6.8 19.2 2.8 7.6 8.9 2.1 2 0 0 2 2 2 0 Protein Family FAM60A DUF4407 PF14362.1 KKK26992.1 - 5.7 5.8 9.9 7.3 5.4 6.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) APG6 PF04111.7 KKK26992.1 - 6.3 5.7 12.2 8.2 5.3 8.5 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 4HBT PF03061.17 KKK26993.1 - 0.007 16.4 0.1 4.6 7.4 0.0 2.6 2 0 0 2 2 2 2 Thioesterase superfamily Asp PF00026.18 KKK26994.1 - 4.2e-70 236.5 7.6 4.2e-70 236.5 5.3 1.7 2 0 0 2 2 2 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KKK26994.1 - 7e-12 45.6 0.5 7e-12 45.6 0.3 2.3 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 KKK26994.1 - 2.4e-07 31.1 0.1 0.037 14.5 0.0 2.8 2 0 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.1 KKK26994.1 - 0.0055 16.2 0.0 0.11 12.0 0.0 2.4 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal Pkinase PF00069.20 KKK26995.1 - 5.3e-26 91.3 0.0 8.7e-26 90.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK26995.1 - 2.9e-09 36.3 0.0 4e-08 32.6 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase DSPc PF00782.15 KKK26996.1 - 2.8e-25 88.4 0.0 3.7e-25 88.0 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KKK26996.1 - 0.0003 20.2 0.0 0.00048 19.5 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.7 KKK26996.1 - 0.016 14.1 0.0 0.021 13.6 0.0 1.1 1 0 0 1 1 1 0 Initiator tRNA phosphoribosyl transferase Y_phosphatase3 PF13350.1 KKK26996.1 - 0.045 14.0 0.0 0.077 13.2 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family IBR PF01485.16 KKK26996.1 - 0.071 12.9 2.2 0.56 10.1 0.2 2.4 2 0 0 2 2 2 0 IBR domain PTPlike_phytase PF14566.1 KKK26996.1 - 0.1 12.6 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate Peptidase_M24 PF00557.19 KKK26997.1 - 1.4e-17 64.0 0.0 1.6e-17 63.7 0.0 1.0 1 0 0 1 1 1 1 Metallopeptidase family M24 Methyltransf_18 PF12847.2 KKK26998.1 - 1.2e-17 64.4 0.0 2.9e-17 63.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KKK26998.1 - 4.2e-11 42.6 0.0 1e-08 34.8 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KKK26998.1 - 3e-06 27.0 0.0 7.6e-06 25.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KKK26998.1 - 1.3e-05 25.1 0.1 6.4e-05 22.9 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 KKK26998.1 - 0.0003 21.2 0.0 0.0025 18.2 0.0 2.6 3 0 0 3 3 2 1 Methyltransferase domain Fungal_trans PF04082.13 KKK26998.1 - 0.00051 18.9 0.2 0.0014 17.5 0.1 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Methyltransf_25 PF13649.1 KKK26998.1 - 0.0027 18.0 0.0 0.0087 16.3 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 KKK26998.1 - 0.0039 16.5 0.1 0.0076 15.6 0.1 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_12 PF08242.7 KKK26998.1 - 0.013 15.9 0.0 0.076 13.4 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain FtsJ PF01728.14 KKK26998.1 - 0.073 13.0 0.0 0.19 11.7 0.0 1.7 1 0 0 1 1 1 0 FtsJ-like methyltransferase Cytomega_TRL10 PF06084.6 KKK26998.1 - 2.9 7.6 9.6 5.8 6.6 0.2 2.5 2 0 0 2 2 2 0 Cytomegalovirus TRL10 protein DSPc PF00782.15 KKK26999.1 - 5.4e-23 81.0 0.0 6.3e-22 77.5 0.0 2.1 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Cript PF10235.4 KKK27001.1 - 5.5e-38 129.2 1.7 5.5e-38 129.2 1.2 1.7 1 1 1 2 2 2 1 Microtubule-associated protein CRIPT DZR PF12773.2 KKK27001.1 - 0.00022 20.9 11.5 0.0053 16.5 6.1 2.6 2 1 1 3 3 3 2 Double zinc ribbon zf-ribbon_3 PF13248.1 KKK27001.1 - 0.001 18.2 8.4 0.16 11.2 0.9 3.3 2 1 1 3 3 3 2 zinc-ribbon domain eIF-4B PF06273.6 KKK27001.1 - 0.011 14.5 1.1 0.011 14.5 0.8 1.1 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B Rad50_zn_hook PF04423.9 KKK27001.1 - 0.014 14.8 3.4 0.028 13.8 2.4 1.5 1 0 0 1 1 1 0 Rad50 zinc hook motif zinc_ribbon_2 PF13240.1 KKK27001.1 - 0.18 11.3 11.2 7 6.2 0.1 3.2 2 1 1 3 3 3 0 zinc-ribbon domain zf-HYPF PF07503.7 KKK27001.1 - 0.61 9.5 11.0 0.71 9.3 3.9 2.3 2 0 0 2 2 2 0 HypF finger DUF2616 PF11077.3 KKK27001.1 - 1 8.8 6.6 0.066 12.7 1.3 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2616) Prok-RING_4 PF14447.1 KKK27001.1 - 1.2 8.7 6.2 2.7 7.6 0.6 2.5 3 0 0 3 3 3 0 Prokaryotic RING finger family 4 DUF1272 PF06906.6 KKK27001.1 - 2.5 8.0 13.1 7.2 6.5 5.9 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1272) zf-C3HC4_3 PF13920.1 KKK27001.1 - 3.2 7.5 14.3 46 3.7 7.1 3.0 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) DUF581 PF04570.9 KKK27001.1 - 4.3 6.7 12.2 20 4.5 1.3 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF581) Kazal_2 PF07648.10 KKK27001.1 - 4.8 7.2 10.4 2.6 8.0 2.4 3.0 3 0 0 3 3 3 0 Kazal-type serine protease inhibitor domain DUF2039 PF10217.4 KKK27001.1 - 4.9 7.2 17.8 1.7 8.7 7.8 2.4 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2039) zf-TFIIB PF13453.1 KKK27001.1 - 5.2 6.3 7.3 2.9 7.1 0.0 2.8 3 0 0 3 3 3 0 Transcription factor zinc-finger MRP-L46 PF11788.3 KKK27002.1 - 1.5e-35 122.2 1.2 3.1e-35 121.1 0.8 1.6 1 0 0 1 1 1 1 39S mitochondrial ribosomal protein L46 NUDIX PF00293.23 KKK27002.1 - 0.0024 17.5 0.0 0.0048 16.5 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain CAF1 PF04857.15 KKK27003.1 - 2.3e-46 158.2 0.0 2.9e-46 157.9 0.0 1.2 1 0 0 1 1 1 1 CAF1 family ribonuclease Acetyltransf_1 PF00583.19 KKK27005.1 - 7.1e-19 67.6 0.0 1.1e-18 67.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 KKK27005.1 - 1.2e-11 44.2 0.1 1.9e-11 43.5 0.1 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 KKK27005.1 - 1.4e-09 38.0 0.0 2.4e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 KKK27005.1 - 2.3e-09 37.5 0.0 3e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KKK27005.1 - 2.3e-09 37.2 0.0 3.7e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KKK27005.1 - 1.9e-07 31.0 0.0 3.1e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KKK27005.1 - 1.1e-06 28.4 0.0 2.1e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain GNAT_acetyltran PF12746.2 KKK27005.1 - 0.00038 19.3 0.1 0.00058 18.7 0.0 1.2 1 0 0 1 1 1 1 GNAT acetyltransferase Acetyltransf_CG PF14542.1 KKK27005.1 - 0.00046 20.0 0.0 0.00084 19.1 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase DUF3749 PF12568.3 KKK27005.1 - 0.029 13.9 0.1 0.041 13.4 0.1 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 KKK27005.1 - 0.077 12.9 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Glyco_transf_90 PF05686.7 KKK27007.1 - 3.5e-29 101.7 0.5 4.5e-29 101.3 0.4 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 90 Glyco_trans_1_2 PF13524.1 KKK27007.1 - 0.0091 16.2 0.1 0.023 14.9 0.1 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 ACCA PF03255.9 KKK27007.1 - 0.1 12.1 0.0 0.99 8.9 0.0 2.4 3 0 0 3 3 3 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit LCAT PF02450.10 KKK27008.1 - 4.7e-93 312.2 0.0 5.7e-93 311.9 0.0 1.0 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase HutD PF05962.6 KKK27008.1 - 0.0098 15.6 0.0 0.018 14.7 0.0 1.3 1 0 0 1 1 1 1 HutD RasGAP PF00616.14 KKK27009.1 - 1.6e-55 187.8 0.1 4.5e-55 186.3 0.0 1.8 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.10 KKK27009.1 - 1.9e-32 111.8 5.9 1.9e-32 111.8 4.1 2.8 3 0 0 3 3 3 1 RasGAP C-terminus MeMO_Hyd_G PF02964.11 KKK27009.1 - 0.033 14.0 0.2 0.084 12.7 0.1 1.6 1 0 0 1 1 1 0 Methane monooxygenase, hydrolase gamma chain CRAL_TRIO PF00650.15 KKK27010.1 - 1.3e-37 128.7 0.0 2.2e-37 128.0 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 KKK27010.1 - 3.8e-10 39.7 0.6 1.7e-09 37.6 0.1 2.3 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 KKK27010.1 - 7e-06 26.0 0.0 2.2e-05 24.3 0.0 1.8 1 1 0 1 1 1 1 Divergent CRAL/TRIO domain TMF_DNA_bd PF12329.3 KKK27010.1 - 0.087 12.6 0.0 7.5 6.4 0.0 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Mis14 PF08641.7 KKK27011.1 - 1.5e-30 106.0 6.0 1.5e-30 106.0 4.2 2.7 2 1 1 3 3 3 1 Kinetochore protein Mis14 like BSP_II PF05432.6 KKK27011.1 - 0.00087 18.6 9.2 0.0012 18.1 6.4 1.4 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) SRP-alpha_N PF04086.8 KKK27011.1 - 0.0059 16.0 9.2 0.0079 15.6 6.4 1.1 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal Myc_N PF01056.13 KKK27011.1 - 0.017 14.3 5.3 0.023 13.8 3.7 1.3 1 0 0 1 1 1 0 Myc amino-terminal region Daxx PF03344.10 KKK27011.1 - 0.023 13.2 14.0 0.026 13.0 9.7 1.1 1 0 0 1 1 1 0 Daxx Family Nop14 PF04147.7 KKK27011.1 - 0.12 10.2 18.9 0.15 9.9 13.1 1.1 1 0 0 1 1 1 0 Nop14-like family Ycf1 PF05758.7 KKK27011.1 - 0.14 9.8 5.5 0.15 9.7 3.8 1.0 1 0 0 1 1 1 0 Ycf1 DUF4611 PF15387.1 KKK27011.1 - 0.15 12.1 21.8 0.13 12.4 7.5 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4611) TFIIF_alpha PF05793.7 KKK27011.1 - 1.2 7.4 22.7 1.6 6.9 15.7 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SAPS PF04499.10 KKK27011.1 - 1.3 7.5 6.8 1.5 7.3 4.7 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Hid1 PF12722.2 KKK27011.1 - 2.3 5.7 7.4 3 5.4 5.2 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CDC45 PF02724.9 KKK27011.1 - 2.5 6.0 21.5 3.4 5.5 14.9 1.1 1 0 0 1 1 1 0 CDC45-like protein IFT57 PF10498.4 KKK27011.1 - 2.6 6.6 12.3 3.5 6.2 8.5 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 NARP1 PF12569.3 KKK27011.1 - 2.7 6.6 13.9 4 6.0 9.6 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Sporozoite_P67 PF05642.6 KKK27011.1 - 2.9 5.6 7.3 3.9 5.2 5.1 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen NOA36 PF06524.7 KKK27011.1 - 3 7.0 8.8 4.2 6.5 6.1 1.3 1 0 0 1 1 1 0 NOA36 protein Apt1 PF10351.4 KKK27011.1 - 3 6.6 10.4 4.2 6.1 7.2 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Dicty_REP PF05086.7 KKK27011.1 - 3.6 5.2 6.2 5.3 4.6 4.3 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Pex24p PF06398.6 KKK27012.1 - 7e-06 25.0 1.9 1e-05 24.5 1.3 1.3 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Ribonuc_L-PSP PF01042.16 KKK27013.1 - 1.4e-16 60.3 0.0 2.2e-07 30.6 0.0 3.4 3 0 0 3 3 3 3 Endoribonuclease L-PSP ATP_bind_4 PF01902.12 KKK27013.1 - 1.4e-15 57.2 0.0 9.4e-05 21.8 0.0 3.6 3 0 0 3 3 3 3 ATP-binding region Myc_N PF01056.13 KKK27013.1 - 0.05 12.7 3.0 0.086 11.9 2.1 1.3 1 0 0 1 1 1 0 Myc amino-terminal region zf-C2H2 PF00096.21 KKK27014.1 - 5.2e-12 45.3 12.1 2.6e-06 27.4 0.4 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KKK27014.1 - 1.4e-09 37.5 11.5 0.00028 20.9 3.7 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KKK27014.1 - 3.7e-07 30.1 11.8 3.1e-06 27.1 3.0 3.3 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.3 KKK27014.1 - 1e-05 25.5 5.2 0.0025 17.8 0.6 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KKK27014.1 - 9.3e-05 22.4 4.9 0.0036 17.4 0.3 2.7 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 KKK27014.1 - 0.01 15.7 8.8 0.015 15.2 0.2 2.8 2 1 0 2 2 2 0 C2H2-type zinc finger zf-UBP PF02148.14 KKK27014.1 - 0.16 12.0 1.4 1.9 8.6 1.0 2.3 1 1 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein zf-C2H2_2 PF12756.2 KKK27014.1 - 0.51 10.4 3.5 8.9 6.4 0.3 2.4 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-BED PF02892.10 KKK27014.1 - 3.4 7.4 7.2 1 9.1 1.4 2.2 1 1 1 2 2 2 0 BED zinc finger MOSC_N PF03476.11 KKK27015.1 - 5.7e-30 103.4 0.0 1e-29 102.6 0.0 1.4 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.12 KKK27015.1 - 1.3e-24 86.2 0.0 2.5e-24 85.2 0.0 1.5 1 0 0 1 1 1 1 MOSC domain Aminotran_5 PF00266.14 KKK27015.1 - 3e-22 78.8 0.0 4.9e-22 78.1 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class-V Peptidase_M1 PF01433.15 KKK27016.1 - 2.7e-128 428.4 7.7 6.7e-65 219.6 0.3 2.1 1 1 1 2 2 2 2 Peptidase family M1 ERAP1_C PF11838.3 KKK27016.1 - 9.3e-95 317.5 0.4 6.7e-94 314.7 0.1 2.1 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 KKK27016.1 - 1.5e-19 70.3 0.1 2.8e-19 69.4 0.1 1.5 1 0 0 1 1 1 1 Peptidase MA superfamily DUF2808 PF10989.3 KKK27016.1 - 0.0064 16.1 0.1 0.015 14.9 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2808) DUF3543 PF12063.3 KKK27017.1 - 1.4e-98 328.8 0.0 2.1e-98 328.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) Pkinase PF00069.20 KKK27017.1 - 1.6e-62 211.0 0.0 2.4e-62 210.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK27017.1 - 6.8e-42 143.3 0.0 1.2e-41 142.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase CTP_transf_1 PF01148.15 KKK27018.1 - 3.5e-05 23.6 9.5 0.00045 19.9 2.1 3.1 4 0 0 4 4 4 2 Cytidylyltransferase family Med9 PF07544.8 KKK27018.1 - 0.24 11.1 0.4 0.58 9.9 0.3 1.5 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 DUF912 PF06024.7 KKK27019.1 - 0.03 14.3 0.1 0.53 10.3 0.0 2.5 1 1 1 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF1180 PF06679.7 KKK27019.1 - 2.6 7.9 0.0 2.6 7.9 0.0 3.4 5 0 0 5 5 5 0 Protein of unknown function (DUF1180) DUF4192 PF13830.1 KKK27019.1 - 8 5.9 12.7 17 4.9 8.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) Cep57_MT_bd PF06657.8 KKK27020.1 - 2.8e-28 97.6 0.3 2.8e-28 97.6 0.2 3.5 4 0 0 4 4 4 1 Centrosome microtubule-binding domain of Cep57 MFS_1 PF07690.11 KKK27020.1 - 2.2e-26 92.4 19.6 3.5e-26 91.7 13.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Cep57_CLD_2 PF14197.1 KKK27020.1 - 3.8e-20 71.5 10.4 3.8e-20 71.5 7.2 4.2 4 0 0 4 4 4 1 Centrosome localisation domain of PPC89 MFS_3 PF05977.8 KKK27020.1 - 0.011 13.8 1.0 0.02 13.0 0.7 1.3 1 0 0 1 1 1 0 Transmembrane secretion effector DAHP_synth_2 PF01474.11 KKK27022.1 - 2.1e-44 151.5 0.0 2.4e-44 151.4 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family DEAD PF00270.24 KKK27023.1 - 5.3e-41 139.9 0.0 3.5e-40 137.2 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KKK27023.1 - 9.6e-26 89.4 0.1 2.3e-25 88.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF2986 PF11661.3 KKK27023.1 - 0.0022 18.2 3.4 0.0079 16.5 2.3 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2986) DUF3334 PF11813.3 KKK27023.1 - 0.098 12.1 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3334) DUF4282 PF14110.1 KKK27024.1 - 0.0099 16.0 12.7 0.024 14.7 4.5 2.5 2 1 0 2 2 2 1 Domain of unknown function (DUF4282) DUF2244 PF10003.4 KKK27024.1 - 0.052 12.9 9.2 0.16 11.2 0.1 2.5 2 1 0 2 2 2 0 Integral membrane protein (DUF2244) Shisa PF13908.1 KKK27024.1 - 0.56 10.3 1.7 5.7 7.0 1.0 2.1 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator HemY_N PF07219.8 KKK27024.1 - 2.9 7.5 8.0 1.5 8.4 0.9 2.4 2 0 0 2 2 2 0 HemY protein N-terminus PLDc_N PF13396.1 KKK27024.1 - 3.6 7.3 11.4 1 9.0 0.9 3.3 3 0 0 3 3 3 0 Phospholipase_D-nuclease N-terminal PAP2 PF01569.16 KKK27025.1 - 3.8e-18 65.4 2.3 1.9e-17 63.1 1.6 2.0 1 1 0 1 1 1 1 PAP2 superfamily But2 PF09792.4 KKK27026.1 - 7.7e-60 200.7 2.1 7.7e-60 200.7 1.5 3.1 3 1 0 3 3 3 1 Ubiquitin 3 binding protein But2 C-terminal domain PAT1 PF09770.4 KKK27026.1 - 4.6 5.3 17.5 6 4.9 12.1 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Prefoldin_3 PF13758.1 KKK27027.1 - 9.1e-22 76.7 0.1 2.7e-21 75.1 0.1 1.8 1 0 0 1 1 1 1 Prefoldin subunit DUF3835 PF12927.2 KKK27027.1 - 0.025 15.5 1.0 0.025 15.5 0.7 4.2 3 2 0 3 3 3 0 Domain of unknown function (DUF3835) MAT1 PF06391.8 KKK27028.1 - 2.6e-35 121.8 14.7 3.2e-35 121.5 10.2 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4 PF00097.20 KKK27028.1 - 0.00026 20.5 4.6 0.00083 18.9 3.3 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KKK27028.1 - 0.0013 18.6 5.9 0.003 17.5 4.1 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KKK27028.1 - 0.0015 18.1 6.0 0.0029 17.2 4.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KKK27028.1 - 0.0046 16.7 5.7 0.01 15.6 3.9 1.5 1 1 0 1 1 1 1 Ring finger domain zf-RING_4 PF14570.1 KKK27028.1 - 0.01 15.3 5.0 0.14 11.7 1.4 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_5 PF14634.1 KKK27028.1 - 0.023 14.4 9.4 0.25 11.1 7.0 2.1 1 1 1 2 2 2 0 zinc-RING finger domain VID27 PF08553.5 KKK27028.1 - 0.35 9.0 5.5 0.47 8.6 3.8 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein APG6 PF04111.7 KKK27028.1 - 3 6.8 8.3 4.9 6.1 5.8 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 NGP1NT PF08153.7 KKK27030.1 - 5.6e-48 162.1 0.0 9e-48 161.5 0.0 1.3 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.18 KKK27030.1 - 1.2e-18 67.0 0.1 1e-14 54.4 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 KKK27030.1 - 0.00026 20.3 0.0 0.00087 18.5 0.0 1.8 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 KKK27030.1 - 0.00044 20.1 0.1 0.11 12.3 0.0 3.3 2 1 1 3 3 3 1 Dynamin family Arf PF00025.16 KKK27030.1 - 0.0029 16.8 0.0 0.13 11.4 0.0 2.3 2 0 0 2 2 2 1 ADP-ribosylation factor family DUF258 PF03193.11 KKK27030.1 - 0.0077 15.4 0.0 0.015 14.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 SusD-like_3 PF14322.1 KKK27030.1 - 0.12 12.3 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Starch-binding associating with outer membrane DUF605 PF04652.11 KKK27031.1 - 2.7 7.3 11.7 3.2 7.0 8.1 1.1 1 0 0 1 1 1 0 Vta1 like Suf PF05843.9 KKK27032.1 - 1.3e-06 28.3 0.4 0.00024 20.9 0.1 3.1 3 0 0 3 3 3 1 Suppressor of forked protein (Suf) FAT PF02259.18 KKK27032.1 - 0.0021 17.0 1.2 0.0085 15.1 0.1 2.3 2 2 1 3 3 3 1 FAT domain TPR_16 PF13432.1 KKK27032.1 - 0.048 14.3 8.2 1.8 9.3 0.0 5.3 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_19 PF14559.1 KKK27032.1 - 0.077 13.3 0.1 9.2 6.6 0.0 3.4 1 1 3 4 4 4 0 Tetratricopeptide repeat Aldose_epim PF01263.15 KKK27033.1 - 2.9e-40 138.2 0.0 3.3e-40 138.0 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase Pkinase PF00069.20 KKK27034.1 - 1.1e-40 139.4 0.0 4.6e-40 137.4 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK27034.1 - 2.1e-28 99.1 0.0 2.9e-28 98.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KKK27034.1 - 0.0018 17.3 0.0 0.0043 16.0 0.0 1.6 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 KKK27034.1 - 0.0045 16.7 2.5 0.038 13.7 0.1 3.0 2 1 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 KKK27034.1 - 0.013 14.5 0.0 0.051 12.6 0.0 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.6 KKK27034.1 - 0.23 10.2 0.0 0.57 8.9 0.0 1.5 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase Ric8 PF10165.4 KKK27035.1 - 1e-134 449.7 0.0 1.3e-134 449.3 0.0 1.1 1 0 0 1 1 1 1 Guanine nucleotide exchange factor synembryn Rif1_N PF12231.3 KKK27036.1 - 1.4e-145 484.9 0.1 2.5e-145 484.1 0.0 1.5 2 0 0 2 2 2 1 Rap1-interacting factor 1 N terminal DLH PF01738.13 KKK27037.1 - 1.9e-17 63.3 0.0 8.2e-14 51.4 0.0 2.1 2 0 0 2 2 2 2 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 KKK27037.1 - 0.00013 21.7 0.0 0.00028 20.6 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KKK27037.1 - 0.03 14.2 0.0 0.092 12.6 0.0 2.0 1 1 0 1 1 1 0 Alpha/beta hydrolase family Gal_mutarotas_2 PF13802.1 KKK27037.1 - 0.033 14.0 0.1 0.073 12.9 0.1 1.5 1 0 0 1 1 1 0 Galactose mutarotase-like ABC_membrane PF00664.18 KKK27038.1 - 2.6e-68 230.4 27.0 3.1e-38 131.7 5.2 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KKK27038.1 - 1.4e-56 190.5 0.0 1.2e-28 100.1 0.0 2.8 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 KKK27038.1 - 1.2e-18 67.1 1.5 1.4e-07 31.0 0.0 4.3 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain Polysacc_synt_4 PF04669.8 KKK27038.1 - 1.1e-16 60.8 1.1 3.1e-16 59.2 0.7 1.8 1 1 0 1 1 1 1 Polysaccharide biosynthesis AAA_21 PF13304.1 KKK27038.1 - 2.9e-12 47.1 4.2 0.0088 16.0 0.6 4.6 4 1 0 4 4 3 3 AAA domain AAA_29 PF13555.1 KKK27038.1 - 2e-08 33.6 2.4 0.0031 17.0 0.3 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.1 KKK27038.1 - 5.2e-08 32.5 0.0 0.12 11.7 0.0 4.1 4 0 0 4 4 4 2 AAA domain AAA_17 PF13207.1 KKK27038.1 - 2.4e-07 31.5 0.5 0.031 15.0 0.0 3.2 2 1 0 2 2 2 2 AAA domain AAA_22 PF13401.1 KKK27038.1 - 8.7e-07 29.1 4.0 0.0046 17.0 0.0 4.6 3 2 0 3 3 3 1 AAA domain AAA_18 PF13238.1 KKK27038.1 - 5.8e-06 26.6 1.0 0.19 12.0 0.0 3.7 4 0 0 4 4 4 2 AAA domain AAA_16 PF13191.1 KKK27038.1 - 2.5e-05 24.3 0.3 0.072 13.0 0.2 3.2 2 1 0 2 2 2 2 AAA ATPase domain AAA_10 PF12846.2 KKK27038.1 - 2.8e-05 23.6 4.3 0.098 12.0 0.3 4.0 4 0 0 4 4 4 2 AAA-like domain DUF258 PF03193.11 KKK27038.1 - 5.6e-05 22.3 0.1 0.4 9.8 0.0 2.8 3 0 0 3 3 3 2 Protein of unknown function, DUF258 ABC_ATPase PF09818.4 KKK27038.1 - 0.00011 20.9 2.7 0.14 10.7 0.0 3.7 4 0 0 4 4 4 1 Predicted ATPase of the ABC class FtsK_SpoIIIE PF01580.13 KKK27038.1 - 0.001 18.5 0.0 1.8 7.9 0.0 2.5 2 0 0 2 2 2 2 FtsK/SpoIIIE family MMR_HSR1 PF01926.18 KKK27038.1 - 0.001 18.9 0.7 0.88 9.5 0.0 3.2 2 1 0 2 2 2 1 50S ribosome-binding GTPase SbcCD_C PF13558.1 KKK27038.1 - 0.0019 18.0 0.0 3.6 7.5 0.0 3.0 2 0 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.1 KKK27038.1 - 0.0037 17.1 0.0 4.1 7.2 0.0 3.0 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.12 KKK27038.1 - 0.006 16.4 5.3 0.092 12.5 0.1 3.2 3 0 0 3 3 3 1 Domain of unknown function DUF87 AAA_5 PF07728.9 KKK27038.1 - 0.016 14.9 0.2 5.4 6.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_13 PF13166.1 KKK27038.1 - 0.019 13.4 3.9 6.1 5.1 0.1 3.5 3 0 0 3 3 3 0 AAA domain Miro PF08477.8 KKK27038.1 - 0.021 15.3 0.1 15 6.1 0.0 3.7 3 0 0 3 3 3 0 Miro-like protein KaiC PF06745.8 KKK27038.1 - 0.024 13.7 8.4 4.4 6.3 0.3 3.8 4 0 0 4 4 4 0 KaiC AAA_15 PF13175.1 KKK27038.1 - 0.028 13.5 8.2 0.12 11.3 0.0 4.2 5 0 0 5 5 5 0 AAA ATPase domain MobB PF03205.9 KKK27038.1 - 0.029 14.0 1.3 3.3 7.4 0.0 2.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 KKK27038.1 - 0.034 13.8 0.3 13 5.4 0.4 2.8 2 0 0 2 2 2 0 NACHT domain AAA_23 PF13476.1 KKK27038.1 - 0.034 14.4 6.1 0.96 9.7 0.0 3.0 3 0 0 3 3 3 0 AAA domain APS_kinase PF01583.15 KKK27038.1 - 0.043 13.4 0.3 12 5.5 0.0 2.6 2 0 0 2 2 2 0 Adenylylsulphate kinase DUF3987 PF13148.1 KKK27038.1 - 0.063 11.8 1.5 4 5.8 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3987) Sigma54_activat PF00158.21 KKK27038.1 - 0.082 12.3 0.0 9.2 5.7 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain RNA_helicase PF00910.17 KKK27038.1 - 0.13 12.4 0.0 26 5.0 0.0 2.6 2 0 0 2 2 2 0 RNA helicase zf-RING_2 PF13639.1 KKK27039.1 - 1.1e-16 60.3 4.5 2e-16 59.4 3.1 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 KKK27039.1 - 1.7e-10 40.7 4.3 2.9e-10 39.9 3.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KKK27039.1 - 2.9e-09 36.4 2.8 5.3e-09 35.5 2.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KKK27039.1 - 7.7e-09 35.1 3.2 1.4e-08 34.3 2.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 KKK27039.1 - 1e-07 31.9 4.8 3.1e-07 30.3 3.3 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 KKK27039.1 - 1.6e-07 30.8 2.1 2.8e-07 30.0 1.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KKK27039.1 - 2.5e-06 27.1 2.0 7.1e-06 25.6 1.4 1.9 1 0 0 1 1 1 1 RING-type zinc-finger Rtf2 PF04641.7 KKK27039.1 - 0.00011 21.5 0.5 0.022 13.9 0.0 2.1 2 0 0 2 2 2 1 Rtf2 RING-finger zf-C3HC4_4 PF15227.1 KKK27039.1 - 0.00014 21.7 3.8 0.00014 21.7 2.6 2.1 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING RINGv PF12906.2 KKK27039.1 - 0.0012 18.8 1.1 0.0029 17.5 0.8 1.7 1 1 0 1 1 1 1 RING-variant domain zf-RING_4 PF14570.1 KKK27039.1 - 0.0013 18.2 4.0 0.0023 17.4 2.7 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain FANCL_C PF11793.3 KKK27039.1 - 0.0014 18.5 3.3 0.0052 16.7 2.3 2.0 1 1 0 1 1 1 1 FANCL C-terminal domain PHD PF00628.24 KKK27039.1 - 0.0026 17.4 2.4 0.0057 16.3 1.7 1.6 1 0 0 1 1 1 1 PHD-finger YfhO PF09586.5 KKK27039.1 - 0.0026 15.8 0.1 0.0034 15.5 0.0 1.0 1 0 0 1 1 1 1 Bacterial membrane protein YfhO APC_CDC26 PF10471.4 KKK27039.1 - 0.0043 17.7 8.0 0.01 16.5 5.5 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex APC subunit 1 Chordopox_A13L PF05961.6 KKK27039.1 - 0.005 16.7 0.7 0.36 10.8 0.4 2.3 2 0 0 2 2 2 1 Chordopoxvirus A13L protein Spt20 PF12090.3 KKK27039.1 - 0.006 15.9 0.5 0.0072 15.6 0.4 1.2 1 0 0 1 1 1 1 Spt20 family Prok-RING_1 PF14446.1 KKK27039.1 - 0.008 15.8 4.6 0.0083 15.8 0.5 2.2 1 1 1 2 2 2 1 Prokaryotic RING finger family 1 WASH-7_C PF14746.1 KKK27039.1 - 0.011 15.3 0.3 0.014 14.9 0.2 1.1 1 0 0 1 1 1 0 WASH complex subunit 7, C-terminal zf-Apc11 PF12861.2 KKK27039.1 - 0.021 14.6 4.4 0.021 14.6 3.1 2.5 2 1 0 2 2 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Suf PF05843.9 KKK27039.1 - 0.022 14.4 0.8 0.026 14.2 0.5 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) zf-Nse PF11789.3 KKK27039.1 - 0.036 13.5 1.0 0.067 12.7 0.7 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING-like PF08746.6 KKK27039.1 - 0.041 13.8 2.6 0.11 12.5 1.8 1.8 1 1 0 1 1 1 0 RING-like domain Activator_LAG-3 PF11498.3 KKK27039.1 - 0.089 11.5 18.8 0.13 10.9 13.0 1.3 1 0 0 1 1 1 0 Transcriptional activator LAG-3 TMEM154 PF15102.1 KKK27039.1 - 0.32 10.6 4.3 20 4.8 0.0 2.2 2 0 0 2 2 2 0 TMEM154 protein family MFS_Mycoplasma PF07672.8 KKK27039.1 - 0.56 9.3 3.5 0.21 10.7 0.5 1.6 1 1 1 2 2 2 0 Mycoplasma MFS transporter DUF788 PF05620.6 KKK27039.1 - 0.98 9.2 3.4 5.4 6.8 1.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF788) PAT1 PF09770.4 KKK27039.1 - 1 7.5 14.6 1.2 7.3 10.1 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4175 PF13779.1 KKK27039.1 - 3.1 5.3 16.6 4.2 4.9 11.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Med3 PF11593.3 KKK27039.1 - 3.1 6.9 13.6 4.2 6.5 9.4 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal TMEM247 PF15444.1 KKK27039.1 - 3.5 7.3 6.6 5.2 6.8 4.5 1.2 1 0 0 1 1 1 0 Transmembrane protein 247 DUF2489 PF10675.4 KKK27039.1 - 4.6 6.9 12.1 7.1 6.3 8.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2489) Thioredoxin_4 PF13462.1 KKK27039.1 - 7.7 6.5 7.5 1.2 9.1 1.7 1.9 2 0 0 2 2 2 0 Thioredoxin AA_permease PF00324.16 KKK27040.1 - 1.5e-135 452.2 37.6 1.7e-135 452.1 26.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KKK27040.1 - 8.8e-36 123.3 41.0 1.1e-35 122.9 28.4 1.1 1 0 0 1 1 1 1 Amino acid permease Pkinase PF00069.20 KKK27041.1 - 1.4e-29 103.0 0.0 2e-29 102.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK27041.1 - 3.4e-09 36.1 0.0 0.00061 18.9 0.0 2.0 2 0 0 2 2 2 2 Protein tyrosine kinase DUF3435 PF11917.3 KKK27041.1 - 0.00079 18.2 0.0 0.001 17.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) Sulfotransfer_3 PF13469.1 KKK27042.1 - 0.089 13.7 0.5 0.17 12.7 0.3 1.6 1 1 0 1 1 1 0 Sulfotransferase family Rrf2 PF02082.15 KKK27043.1 - 0.016 15.3 0.0 0.048 13.7 0.0 1.8 1 0 0 1 1 1 0 Transcriptional regulator LacI PF00356.16 KKK27043.1 - 0.02 14.4 0.5 0.049 13.2 0.0 1.9 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family HTH_Crp_2 PF13545.1 KKK27043.1 - 0.062 13.0 0.0 1.1 9.0 0.0 2.7 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain MarR PF01047.17 KKK27043.1 - 0.12 12.0 0.0 1.3 8.7 0.0 2.6 3 0 0 3 3 3 0 MarR family FAD_binding_3 PF01494.14 KKK27044.1 - 4.2e-10 39.2 0.0 1.5e-09 37.3 0.0 1.8 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 KKK27044.1 - 2.1e-06 26.9 0.0 0.034 13.0 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KKK27044.1 - 0.014 14.2 0.1 0.021 13.6 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Imm44 PF15584.1 KKK27044.1 - 0.031 14.1 0.7 9.3 6.1 0.0 2.4 2 0 0 2 2 2 0 Immunity protein 44 HI0933_like PF03486.9 KKK27044.1 - 0.14 10.5 0.0 0.92 7.9 0.1 1.9 2 0 0 2 2 2 0 HI0933-like protein Scytalone_dh PF02982.9 KKK27045.1 - 2.7e-62 209.0 0.6 1.4e-48 164.5 0.1 2.0 2 0 0 2 2 2 2 Scytalone dehydratase SnoaL_4 PF13577.1 KKK27045.1 - 1.6e-05 24.8 0.0 2.4e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain adh_short PF00106.20 KKK27046.1 - 1.4e-29 103.1 1.1 2e-29 102.6 0.8 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KKK27046.1 - 1.8e-28 99.9 0.0 2.2e-28 99.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KKK27046.1 - 8.6e-12 45.0 0.8 1.3e-11 44.4 0.6 1.2 1 0 0 1 1 1 1 KR domain 2-Hacid_dh_C PF02826.14 KKK27046.1 - 0.013 14.6 0.2 0.074 12.2 0.1 2.0 1 1 1 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF1776 PF08643.5 KKK27046.1 - 0.02 14.0 0.0 0.029 13.5 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Epimerase PF01370.16 KKK27046.1 - 0.079 12.3 0.6 0.22 10.9 0.4 1.8 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Methyltransf_18 PF12847.2 KKK27046.1 - 0.081 13.5 0.1 0.2 12.2 0.1 1.7 1 0 0 1 1 1 0 Methyltransferase domain CPSase_L_chain PF00289.17 KKK27046.1 - 0.11 12.6 0.2 0.6 10.2 0.1 2.1 2 0 0 2 2 2 0 Carbamoyl-phosphate synthase L chain, N-terminal domain ketoacyl-synt PF00109.21 KKK27047.1 - 2.3e-67 227.1 0.1 4.3e-67 226.2 0.1 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 KKK27047.1 - 4.3e-50 170.8 0.1 1.1e-48 166.2 0.0 2.2 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 KKK27047.1 - 2.5e-32 111.2 0.9 7.4e-32 109.6 0.6 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain EthD PF07110.6 KKK27047.1 - 2.5e-21 76.4 0.2 1e-20 74.4 0.2 2.2 1 0 0 1 1 1 1 EthD domain PP-binding PF00550.20 KKK27047.1 - 1.6e-09 37.8 0.6 4.9e-09 36.3 0.4 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site DUF1772 PF08592.6 KKK27048.1 - 3.6e-24 85.0 8.5 4.1e-24 84.8 5.9 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) DUF4149 PF13664.1 KKK27048.1 - 0.18 11.8 3.3 0.28 11.2 2.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4149) AflR PF08493.5 KKK27049.1 - 2.3e-26 92.4 0.1 2.3e-26 92.4 0.1 1.8 1 1 1 2 2 2 1 Aflatoxin regulatory protein Zn_clus PF00172.13 KKK27049.1 - 3.4e-07 30.0 8.9 6e-07 29.2 6.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Lactamase_B PF00753.22 KKK27050.1 - 9.4e-25 87.3 3.6 1.4e-24 86.8 2.5 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KKK27050.1 - 6e-05 22.6 1.3 0.00012 21.7 0.9 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain His_Phos_2 PF00328.17 KKK27051.1 - 4.4e-14 52.5 0.0 1.4e-13 50.9 0.0 1.7 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) AMP-binding PF00501.23 KKK27054.1 - 5.5e-79 265.5 0.0 8.1e-79 264.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KKK27054.1 - 0.00011 23.0 0.1 0.00032 21.5 0.0 1.8 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain PBP_like PF12727.2 KKK27054.1 - 0.14 11.0 0.0 0.28 10.1 0.0 1.4 1 0 0 1 1 1 0 PBP superfamily domain PQ-loop PF04193.9 KKK27056.1 - 2.2e-40 135.9 6.9 1.1e-21 76.0 0.2 2.5 2 0 0 2 2 2 2 PQ loop repeat FTR1 PF03239.9 KKK27056.1 - 1.4 7.7 5.5 1.8 7.4 1.9 2.1 2 0 0 2 2 2 0 Iron permease FTR1 family Tcf25 PF04910.9 KKK27057.1 - 8.3e-91 304.6 0.1 1.7e-90 303.5 0.0 1.6 2 0 0 2 2 2 1 Transcriptional repressor TCF25 TPR_16 PF13432.1 KKK27057.1 - 0.0011 19.6 1.9 0.059 14.0 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 KKK27057.1 - 0.005 17.3 0.9 0.27 11.9 0.0 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.1 KKK27057.1 - 0.014 15.0 0.4 0.1 12.2 0.1 2.4 2 0 0 2 2 2 0 TPR repeat TPR_2 PF07719.12 KKK27057.1 - 0.018 14.9 1.1 0.052 13.4 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Cut8_N PF14482.1 KKK27057.1 - 0.11 12.4 2.0 0.31 11.0 1.4 1.7 1 0 0 1 1 1 0 Cut8 proteasome-binding domain Glyco_hydro_53 PF07745.8 KKK27058.1 - 5.5e-103 344.2 0.0 6.2e-103 344.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 53 Glyco_hydro_cc PF11790.3 KKK27058.1 - 0.085 12.2 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase catalytic core Carb_kinase PF01256.12 KKK27059.1 - 3.3e-53 180.4 0.4 3.7e-52 177.0 0.3 2.0 1 1 0 1 1 1 1 Carbohydrate kinase SPT2 PF08243.6 KKK27060.1 - 6.5e-06 26.4 8.6 6.5e-06 26.4 5.9 2.2 2 0 0 2 2 2 1 SPT2 chromatin protein Kelch_4 PF13418.1 KKK27061.1 - 2.5e-07 30.3 2.5 0.016 14.9 0.1 4.2 3 1 0 3 3 3 2 Galactose oxidase, central domain Kelch_5 PF13854.1 KKK27061.1 - 0.048 13.6 0.1 0.23 11.4 0.0 2.2 2 0 0 2 2 2 0 Kelch motif DUF706 PF05153.10 KKK27062.1 - 1.9e-117 391.1 0.9 2.9e-117 390.4 0.6 1.3 1 1 0 1 1 1 1 Family of unknown function (DUF706) HD PF01966.17 KKK27062.1 - 0.027 14.4 0.0 1.2 9.2 0.0 2.5 2 0 0 2 2 2 0 HD domain DUF19 PF01579.13 KKK27062.1 - 0.043 13.7 0.9 0.065 13.2 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF19) Fungal_trans PF04082.13 KKK27063.1 - 1.5e-29 102.7 3.3 1.9e-29 102.3 0.4 2.0 1 1 1 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK27063.1 - 5e-09 35.9 11.4 1.2e-08 34.7 7.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HALZ PF02183.13 KKK27063.1 - 0.0079 15.8 6.6 0.015 15.0 4.6 1.5 1 0 0 1 1 1 1 Homeobox associated leucine zipper EGF_CA PF07645.10 KKK27064.1 - 0.00033 20.5 7.6 0.00033 20.5 5.3 2.0 2 0 0 2 2 2 1 Calcium-binding EGF domain EGF PF00008.22 KKK27064.1 - 0.00058 19.7 5.2 0.0019 18.1 3.6 2.0 1 1 0 1 1 1 1 EGF-like domain EGF_3 PF12947.2 KKK27064.1 - 0.0028 17.5 5.6 0.0028 17.5 3.9 2.3 2 1 0 2 2 2 1 EGF domain cEGF PF12662.2 KKK27064.1 - 0.0089 15.6 0.3 0.0089 15.6 0.2 2.4 2 0 0 2 2 2 1 Complement Clr-like EGF-like CYTL1 PF15153.1 KKK27064.1 - 0.43 10.2 2.1 2 8.1 0.3 2.1 1 1 1 2 2 2 0 Cytokine-like protein 1 FXa_inhibition PF14670.1 KKK27064.1 - 1.5 9.0 15.1 0.4 10.8 6.8 2.7 2 1 0 2 2 2 0 Coagulation Factor Xa inhibitory site AAA PF00004.24 KKK27065.1 - 4.5e-54 182.1 0.0 2.8e-43 147.2 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.6 KKK27065.1 - 3.8e-29 100.5 0.3 8.4e-29 99.4 0.2 1.6 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_16 PF13191.1 KKK27065.1 - 1e-07 32.1 6.7 0.00026 21.0 0.0 4.0 3 1 1 4 4 4 2 AAA ATPase domain AAA_19 PF13245.1 KKK27065.1 - 1.5e-06 27.8 0.2 0.0035 17.0 0.0 3.6 3 0 0 3 3 3 1 Part of AAA domain AAA_2 PF07724.9 KKK27065.1 - 2.3e-06 27.6 0.0 0.069 13.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) NACHT PF05729.7 KKK27065.1 - 2.9e-06 27.0 4.5 0.0017 18.0 0.0 4.1 4 0 0 4 4 4 1 NACHT domain AAA_17 PF13207.1 KKK27065.1 - 6.7e-06 26.9 2.1 0.24 12.2 0.0 3.5 3 0 0 3 3 3 2 AAA domain AAA_14 PF13173.1 KKK27065.1 - 2.9e-05 23.9 0.0 0.22 11.4 0.0 3.3 3 0 0 3 3 2 2 AAA domain AAA_22 PF13401.1 KKK27065.1 - 0.00012 22.2 6.0 0.38 10.9 0.1 4.6 3 2 0 3 3 3 2 AAA domain RuvB_N PF05496.7 KKK27065.1 - 0.00016 20.8 0.0 0.0076 15.3 0.0 2.5 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus RNA_helicase PF00910.17 KKK27065.1 - 0.00018 21.6 0.3 7.6 6.7 0.0 4.1 4 0 0 4 4 4 0 RNA helicase Zeta_toxin PF06414.7 KKK27065.1 - 0.00043 19.4 0.1 0.45 9.5 0.0 2.6 3 0 0 3 3 2 2 Zeta toxin IstB_IS21 PF01695.12 KKK27065.1 - 0.00044 19.7 3.9 0.096 12.0 0.0 2.7 3 0 0 3 3 2 2 IstB-like ATP binding protein AAA_5 PF07728.9 KKK27065.1 - 0.00046 19.9 0.1 0.81 9.4 0.0 3.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 KKK27065.1 - 0.00053 20.3 3.5 0.041 14.2 0.0 3.1 3 1 0 3 3 2 1 AAA domain AAA_33 PF13671.1 KKK27065.1 - 0.00092 19.0 0.0 0.19 11.6 0.0 3.0 2 1 0 2 2 2 1 AAA domain Cytidylate_kin2 PF13189.1 KKK27065.1 - 0.0035 17.2 0.0 1.4 8.7 0.0 3.2 3 0 0 3 3 3 1 Cytidylate kinase-like family TIP49 PF06068.8 KKK27065.1 - 0.0039 15.9 0.0 0.97 8.0 0.0 2.3 2 0 0 2 2 2 1 TIP49 C-terminus AAA_28 PF13521.1 KKK27065.1 - 0.0084 16.0 0.0 5.8 6.8 0.0 2.8 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 KKK27065.1 - 0.012 15.3 1.7 7.6 6.1 0.0 4.0 3 2 1 4 4 4 0 Archaeal ATPase Sigma54_activ_2 PF14532.1 KKK27065.1 - 0.014 15.4 0.0 3.4 7.7 0.0 2.9 2 0 0 2 2 2 0 Sigma-54 interaction domain SKI PF01202.17 KKK27065.1 - 0.016 15.1 0.0 4.8 7.0 0.0 2.6 2 0 0 2 2 2 0 Shikimate kinase Mg_chelatase PF01078.16 KKK27065.1 - 0.016 14.3 1.7 0.16 11.0 0.1 3.0 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI DUF2075 PF09848.4 KKK27065.1 - 0.02 13.8 0.6 1.4 7.7 0.0 2.8 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) T2SE PF00437.15 KKK27065.1 - 0.021 13.7 0.9 0.7 8.7 0.1 3.2 4 0 0 4 4 4 0 Type II/IV secretion system protein KaiC PF06745.8 KKK27065.1 - 0.026 13.6 2.4 1.1 8.3 0.1 3.0 3 0 0 3 3 3 0 KaiC Viral_helicase1 PF01443.13 KKK27065.1 - 0.031 13.7 0.0 0.34 10.4 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Sigma54_activat PF00158.21 KKK27065.1 - 0.037 13.5 0.1 4.8 6.6 0.0 3.3 4 0 0 4 4 4 0 Sigma-54 interaction domain UPF0079 PF02367.12 KKK27065.1 - 0.056 13.0 1.2 1.3 8.6 0.0 2.8 3 0 0 3 3 3 0 Uncharacterised P-loop hydrolase UPF0079 NTPase_1 PF03266.10 KKK27065.1 - 0.059 13.0 0.1 1.4 8.6 0.0 2.5 2 0 0 2 2 2 0 NTPase KAP_NTPase PF07693.9 KKK27065.1 - 0.13 11.1 0.4 2.9 6.7 0.0 2.4 1 1 1 2 2 2 0 KAP family P-loop domain ABC_tran PF00005.22 KKK27065.1 - 0.2 11.9 3.7 20 5.4 0.0 3.9 4 0 0 4 4 4 0 ABC transporter PhoH PF02562.11 KKK27065.1 - 0.22 10.7 1.7 20 4.3 0.0 3.1 3 0 0 3 3 3 0 PhoH-like protein AAA_25 PF13481.1 KKK27065.1 - 0.61 9.4 9.0 4 6.7 0.1 4.5 3 2 1 5 5 4 0 AAA domain cobW PF02492.14 KKK27065.1 - 4 6.8 6.4 8.4 5.7 0.0 2.8 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain MCM PF00493.18 KKK27066.1 - 5.4e-137 456.0 0.2 1e-135 451.8 0.0 2.1 2 0 0 2 2 2 1 MCM2/3/5 family MCM_N PF14551.1 KKK27066.1 - 4.8e-29 101.3 0.2 1.2e-28 100.0 0.2 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 KKK27066.1 - 5.9e-07 28.8 0.0 5.4e-05 22.4 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 KKK27066.1 - 3.9e-06 26.6 0.0 1.1e-05 25.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 KKK27066.1 - 0.012 15.2 0.0 0.066 12.8 0.0 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PGI PF00342.14 KKK27067.1 - 2e-219 729.0 0.4 2.3e-219 728.7 0.2 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase DSHCT PF08148.7 KKK27068.1 - 6.8e-62 207.8 0.7 1.5e-61 206.8 0.5 1.6 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.24 KKK27068.1 - 2.3e-20 72.7 0.0 4.7e-20 71.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KKK27068.1 - 9.7e-07 28.5 0.0 2.2e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KKK27068.1 - 0.0059 16.4 0.1 0.12 12.1 0.0 2.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Pkinase PF00069.20 KKK27069.1 - 8.6e-62 208.6 0.0 1.3e-61 207.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK27069.1 - 2.9e-27 95.3 0.0 4.2e-27 94.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KKK27069.1 - 0.029 13.4 0.0 0.048 12.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KKK27069.1 - 0.076 12.7 0.9 0.18 11.5 0.0 1.8 1 1 0 2 2 2 0 Phosphotransferase enzyme family Pex16 PF08610.5 KKK27069.1 - 5.1 5.9 6.2 7.5 5.4 4.3 1.2 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) Ribosomal_S21 PF01165.15 KKK27070.1 - 1.5e-10 40.3 1.6 2.3e-10 39.7 1.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S21 TPR_1 PF00515.23 KKK27071.1 - 1.2e-12 46.8 4.9 6.8e-06 25.4 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 KKK27071.1 - 1.3e-11 43.9 3.3 3.3e-08 33.0 0.0 3.3 2 1 1 3 3 3 2 TPR repeat TPR_2 PF07719.12 KKK27071.1 - 3.5e-11 42.1 4.8 0.00053 19.7 0.0 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 KKK27071.1 - 3.2e-08 32.7 0.6 0.00062 19.3 0.0 4.6 3 2 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 KKK27071.1 - 1.8e-07 30.9 0.3 0.00071 19.4 0.0 2.9 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 KKK27071.1 - 0.00017 21.1 0.0 0.002 17.7 0.0 2.7 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.1 KKK27071.1 - 0.00046 19.9 0.1 1.2 9.0 0.0 3.2 2 1 1 3 3 3 3 Tetratricopeptide repeat Serglycin PF04360.7 KKK27071.1 - 0.00064 19.4 0.9 0.0015 18.3 0.6 1.5 1 0 0 1 1 1 1 Serglycin TPR_6 PF13174.1 KKK27071.1 - 0.003 17.9 0.7 13 6.5 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat PB1 PF00564.19 KKK27071.1 - 0.0047 16.5 0.1 0.0095 15.5 0.0 1.5 1 0 0 1 1 1 1 PB1 domain TPR_16 PF13432.1 KKK27071.1 - 0.034 14.8 0.1 0.034 14.8 0.0 2.8 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 KKK27071.1 - 0.046 14.3 0.2 1.6 9.5 0.0 3.3 1 1 2 3 3 3 0 Tetratricopeptide repeat Aminotran_1_2 PF00155.16 KKK27072.1 - 7.9e-73 245.4 0.0 9.7e-73 245.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Myb_DNA-binding PF00249.26 KKK27072.1 - 0.095 12.7 0.1 15 5.7 0.0 2.6 2 0 0 2 2 2 0 Myb-like DNA-binding domain Sod_Cu PF00080.15 KKK27073.1 - 1.3e-14 54.5 0.0 1.8e-14 54.1 0.0 1.2 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) HMA PF00403.21 KKK27073.1 - 4.1e-13 49.2 0.0 7.2e-13 48.4 0.0 1.4 1 0 0 1 1 1 1 Heavy-metal-associated domain RRM_1 PF00076.17 KKK27074.1 - 5.9e-06 25.8 0.0 1e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KKK27074.1 - 0.00049 19.8 0.0 0.00096 18.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KKK27074.1 - 0.0036 17.2 0.0 0.0086 16.0 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Rhodanese PF00581.15 KKK27076.1 - 1.9e-13 50.7 0.0 2.5e-13 50.3 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain Methyltransf_28 PF02636.12 KKK27077.1 - 1.9e-79 266.6 0.0 2.7e-79 266.1 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Protocadherin PF08374.6 KKK27077.1 - 0.095 12.3 0.3 0.23 11.0 0.3 1.5 2 0 0 2 2 2 0 Protocadherin tRNA_int_end_N2 PF12928.2 KKK27077.1 - 0.14 11.6 0.1 3.2 7.2 0.0 2.4 2 0 0 2 2 2 0 tRNA-splicing endonuclease subunit sen54 N-term IBN_N PF03810.14 KKK27079.1 - 1.4e-17 63.4 4.1 4.2e-14 52.2 0.0 5.0 5 0 0 5 5 5 2 Importin-beta N-terminal domain Cse1 PF08506.5 KKK27079.1 - 1.8e-07 30.0 0.0 4.5e-07 28.7 0.0 1.7 1 0 0 1 1 1 1 Cse1 Xpo1 PF08389.7 KKK27079.1 - 8.3e-05 22.5 1.6 0.019 14.8 0.0 3.7 3 1 0 3 3 3 1 Exportin 1-like protein HEAT_2 PF13646.1 KKK27079.1 - 8.4e-05 22.7 2.5 0.072 13.3 0.0 3.6 3 1 0 3 3 3 2 HEAT repeats DUF2435 PF10363.4 KKK27079.1 - 0.003 17.4 0.5 0.04 13.8 0.3 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF2435) Terpene_synth_C PF03936.11 KKK27079.1 - 0.023 13.9 0.2 0.097 11.8 0.0 2.1 2 0 0 2 2 2 0 Terpene synthase family, metal binding domain RRM_1 PF00076.17 KKK27080.1 - 3e-07 29.9 0.0 8.8e-07 28.4 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KKK27080.1 - 3.6e-06 26.6 0.0 5.7e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_6 PF14259.1 KKK27080.1 - 1.9e-05 24.5 0.0 4.5e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) SlyX PF04102.7 KKK27081.1 - 0.19 12.1 5.6 2.2 8.7 0.2 2.7 3 0 0 3 3 3 0 SlyX DUF2415 PF10313.4 KKK27082.1 - 1.3e-15 56.8 0.1 4.8e-15 54.9 0.0 2.0 2 0 0 2 2 2 1 Uncharacterised protein domain (DUF2415) WD40 PF00400.27 KKK27082.1 - 0.064 13.1 3.1 3.7 7.5 0.2 3.5 3 0 0 3 3 3 0 WD domain, G-beta repeat CAF-1_p150 PF11600.3 KKK27082.1 - 0.16 11.3 3.1 0.27 10.5 2.2 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal CPSase_L_D2 PF02786.12 KKK27083.1 - 4.1e-107 356.2 0.0 1.6e-83 279.1 0.0 2.2 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.14 KKK27083.1 - 1.6e-41 140.8 0.0 3.9e-41 139.6 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp_4 PF13535.1 KKK27083.1 - 6.9e-38 130.2 0.4 9.6e-22 77.6 0.0 2.6 3 0 0 3 3 3 2 ATP-grasp domain CPSase_L_chain PF00289.17 KKK27083.1 - 2.5e-36 124.1 0.0 6.5e-17 61.6 0.0 2.7 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain ATPgrasp_Ter PF15632.1 KKK27083.1 - 6e-26 90.9 0.0 2.7e-10 39.5 0.0 4.0 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 KKK27083.1 - 1.8e-17 63.2 0.0 8e-08 31.8 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.8 KKK27083.1 - 2.1e-16 59.9 0.1 1.4e-07 31.0 0.0 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus RimK PF08443.6 KKK27083.1 - 1.9e-07 30.7 0.0 0.0025 17.3 0.0 2.6 2 0 0 2 2 2 2 RimK-like ATP-grasp domain ATP-grasp_5 PF13549.1 KKK27083.1 - 0.00016 20.9 0.0 0.13 11.4 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain GARS_A PF01071.14 KKK27083.1 - 0.00074 19.1 0.0 0.23 11.0 0.0 2.5 2 0 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain SET PF00856.23 KKK27084.1 - 1.9e-12 47.7 0.0 6.4e-12 46.0 0.0 1.9 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.13 KKK27084.1 - 1.6e-08 34.2 8.8 4.3e-08 32.8 6.2 1.7 1 1 0 1 1 1 1 MYND finger Ribosomal_S19 PF00203.16 KKK27085.1 - 1.8e-35 120.4 0.3 2.7e-35 119.8 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein S19 SbcD_C PF12320.3 KKK27085.1 - 0.074 13.1 0.5 0.49 10.4 0.0 1.9 1 1 1 2 2 2 0 Type 5 capsule protein repressor C-terminal domain Ribosomal_60s PF00428.14 KKK27086.1 - 1.1e-28 99.4 14.9 1.3e-28 99.2 10.3 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF3138 PF11336.3 KKK27086.1 - 0.053 11.7 2.3 0.056 11.6 1.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) HSP70 PF00012.15 KKK27088.1 - 1.7e-266 884.9 18.3 1.9e-266 884.7 12.7 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KKK27088.1 - 5.6e-16 58.0 8.2 1.8e-14 53.0 1.4 3.0 3 0 0 3 3 3 2 MreB/Mbl protein FGGY_C PF02782.11 KKK27088.1 - 0.001 18.6 0.0 0.0031 17.1 0.0 1.8 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.1 KKK27088.1 - 0.017 14.9 12.0 0.19 11.6 0.1 4.6 3 3 0 3 3 3 0 Cell division protein FtsA Hormone_1 PF00103.15 KKK27088.1 - 0.28 10.5 4.1 0.42 9.9 0.3 2.5 2 1 0 2 2 2 0 Somatotropin hormone family DUF4363 PF14276.1 KKK27088.1 - 0.31 10.7 3.0 0.68 9.6 2.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4363) Hydantoinase_A PF01968.13 KKK27088.1 - 1.5 7.8 7.5 2.2 7.2 0.1 3.3 3 1 0 3 3 3 0 Hydantoinase/oxoprolinase DUF603 PF04645.7 KKK27088.1 - 5.9 6.7 10.2 9.4 6.1 3.5 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF603 DUF481 PF04338.7 KKK27089.1 - 0.13 11.9 0.1 0.18 11.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF481 TMF_TATA_bd PF12325.3 KKK27090.1 - 0.0081 15.8 0.3 0.013 15.2 0.2 1.2 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding YpzG PF14139.1 KKK27090.1 - 0.12 12.2 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 YpzG-like protein PP2C PF00481.16 KKK27091.1 - 2e-44 151.8 0.0 3.6e-44 151.0 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 KKK27091.1 - 1.8e-06 27.4 0.1 4.5e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 KKK27091.1 - 4.7e-05 23.1 0.1 0.21 11.2 0.0 2.9 3 0 0 3 3 3 2 Stage II sporulation protein E (SpoIIE) Methyltransf_16 PF10294.4 KKK27092.1 - 6.5e-07 28.9 0.0 0.0073 15.7 0.0 2.9 3 0 0 3 3 3 2 Putative methyltransferase DUF4587 PF15248.1 KKK27092.1 - 7.1 7.3 7.3 6.5 7.4 4.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4587) NDT80_PhoG PF05224.7 KKK27093.1 - 8e-26 91.1 0.1 1.1e-25 90.7 0.1 1.2 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family eIF3g PF12353.3 KKK27094.1 - 1.6e-46 157.3 2.8 2.4e-46 156.7 2.0 1.3 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.17 KKK27094.1 - 3.2e-17 61.9 0.0 5.4e-17 61.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KKK27094.1 - 9.4e-14 51.1 0.0 2e-13 50.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KKK27094.1 - 3.1e-08 33.3 0.0 6.8e-08 32.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) A_deamin PF02137.13 KKK27094.1 - 0.061 12.6 0.1 0.079 12.2 0.0 1.1 1 0 0 1 1 1 0 Adenosine-deaminase (editase) domain Transp_cyt_pur PF02133.10 KKK27095.1 - 2.5e-49 168.0 39.9 2.8e-49 167.8 27.6 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Beta-lactamase PF00144.19 KKK27097.1 - 1.9e-44 152.0 0.0 4.2e-44 150.9 0.0 1.4 1 1 0 1 1 1 1 Beta-lactamase NMO PF03060.10 KKK27098.1 - 1.3e-60 205.2 4.7 3.9e-59 200.4 3.3 2.0 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 KKK27098.1 - 9.7e-08 31.2 0.2 5.8e-07 28.7 0.1 2.4 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 KKK27098.1 - 2.5e-05 23.3 1.7 4.1e-05 22.6 1.2 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase DHO_dh PF01180.16 KKK27098.1 - 0.016 14.2 0.2 0.028 13.3 0.1 1.4 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase Glu_synthase PF01645.12 KKK27098.1 - 0.021 13.7 1.3 0.045 12.6 0.9 1.5 1 0 0 1 1 1 0 Conserved region in glutamate synthase Radial_spoke_3 PF06098.6 KKK27098.1 - 0.11 11.4 0.0 0.16 10.9 0.0 1.2 1 0 0 1 1 1 0 Radial spoke protein 3 Methyltransf_23 PF13489.1 KKK27099.1 - 9.6e-13 48.1 0.0 1.3e-12 47.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KKK27099.1 - 4.6e-09 36.0 0.0 5.6e-09 35.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KKK27099.1 - 7.3e-09 36.0 0.0 1.2e-08 35.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KKK27099.1 - 3.5e-07 30.7 0.0 5.3e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KKK27099.1 - 2.4e-06 26.8 0.0 3.1e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 KKK27099.1 - 4.1e-06 27.1 0.0 6.5e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 KKK27099.1 - 7e-06 24.9 0.0 1e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_26 PF13659.1 KKK27099.1 - 0.00035 20.5 0.0 0.00094 19.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KKK27099.1 - 0.0013 19.0 0.0 0.0021 18.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DUF938 PF06080.7 KKK27099.1 - 0.0034 16.9 0.0 0.043 13.3 0.0 2.6 1 1 0 1 1 1 1 Protein of unknown function (DUF938) Methyltransf_24 PF13578.1 KKK27099.1 - 0.025 15.3 0.0 0.052 14.3 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain ArfGap PF01412.13 KKK27100.1 - 4.5e-34 116.7 0.7 7.5e-34 116.0 0.5 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf DUF3275 PF11679.3 KKK27100.1 - 6 6.4 7.9 0.17 11.4 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3275) Pterin_bind PF00809.17 KKK27101.1 - 3e-65 219.5 0.0 5.8e-65 218.5 0.0 1.5 1 0 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.15 KKK27101.1 - 1e-39 135.1 0.0 1.7e-39 134.4 0.0 1.4 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) MR_MLE_C PF13378.1 KKK27102.1 - 1e-17 64.0 0.1 2.7e-17 62.7 0.0 1.8 2 0 0 2 2 2 1 Enolase C-terminal domain-like MR_MLE PF01188.16 KKK27102.1 - 2.9e-13 50.1 0.0 1.9e-12 47.5 0.0 2.2 2 0 0 2 2 2 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MR_MLE_N PF02746.11 KKK27102.1 - 3.6e-07 30.1 0.0 7.4e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain TIM21 PF08294.6 KKK27103.1 - 3.9e-42 143.3 0.0 4.8e-42 143.0 0.0 1.1 1 0 0 1 1 1 1 TIM21 Coa1 PF08695.5 KKK27103.1 - 1.5e-05 24.4 0.0 3e-05 23.5 0.0 1.5 1 1 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 PWI PF01480.12 KKK27104.1 - 8.7e-12 44.9 0.6 2e-11 43.8 0.4 1.6 1 0 0 1 1 1 1 PWI domain SUKH_6 PF14568.1 KKK27104.1 - 0.066 13.6 0.0 0.16 12.4 0.0 1.6 1 0 0 1 1 1 0 SMI1-KNR4 cell-wall Rif1_N PF12231.3 KKK27104.1 - 0.28 10.1 0.1 0.4 9.5 0.0 1.1 1 0 0 1 1 1 0 Rap1-interacting factor 1 N terminal 60KD_IMP PF02096.15 KKK27105.1 - 3.8e-16 59.3 0.0 7.4e-16 58.4 0.0 1.4 1 1 0 1 1 1 1 60Kd inner membrane protein DUF1187 PF06688.6 KKK27106.1 - 0.1 12.7 0.1 0.2 11.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1187) zf-H2C2_2 PF13465.1 KKK27107.1 - 1.7e-13 50.1 8.0 5.3e-08 32.7 0.2 3.7 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 KKK27107.1 - 3.2e-12 46.0 13.3 7.4e-06 25.9 2.9 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KKK27107.1 - 2.2e-10 40.1 13.8 0.00014 21.9 3.1 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.2 KKK27107.1 - 0.00015 21.8 2.1 0.04 14.1 0.4 3.1 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KKK27107.1 - 0.00053 20.0 12.2 0.06 13.4 0.4 3.8 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding Elf1 PF05129.8 KKK27107.1 - 0.18 11.5 0.6 0.35 10.6 0.4 1.4 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like LIM PF00412.17 KKK27107.1 - 0.67 10.0 3.6 3.2 7.9 2.5 2.0 1 1 1 2 2 2 0 LIM domain zf-C2H2_6 PF13912.1 KKK27107.1 - 3.5 7.6 9.6 23 5.0 0.2 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger zf-BED PF02892.10 KKK27107.1 - 3.6 7.4 5.8 6.9 6.5 1.4 2.4 1 1 1 2 2 2 0 BED zinc finger Glycos_transf_1 PF00534.15 KKK27108.1 - 8.5e-12 44.8 0.0 1.4e-11 44.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 KKK27108.1 - 7.7e-08 32.5 0.1 2.7e-07 30.8 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 KKK27108.1 - 0.00039 20.1 0.0 0.0012 18.6 0.0 1.8 1 0 0 1 1 1 1 Glycosyltransferase Family 4 MRI PF15325.1 KKK27108.1 - 0.0033 18.3 1.2 0.082 13.8 1.1 2.2 2 0 0 2 2 2 1 Modulator of retrovirus infection Glyco_trans_4_4 PF13579.1 KKK27108.1 - 0.0045 17.1 1.5 0.0067 16.5 0.3 2.0 2 1 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.1 KKK27108.1 - 0.011 16.0 0.1 0.023 14.9 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferases group 1 Pkinase PF00069.20 KKK27109.1 - 5.1e-55 186.4 0.0 8e-38 130.0 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KKK27109.1 - 5e-26 91.3 0.0 1.5e-24 86.4 0.0 2.9 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 KKK27109.1 - 5.8e-06 25.4 0.0 2e-05 23.7 0.0 1.8 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 KKK27109.1 - 1.9e-05 24.5 3.2 3.8e-05 23.5 0.1 2.6 3 0 0 3 3 3 1 Phosphotransferase enzyme family AMP-binding PF00501.23 KKK27111.1 - 2.7e-93 312.6 0.0 3.2e-93 312.3 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KKK27111.1 - 3.3e-10 40.7 0.1 1.1e-09 39.1 0.1 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain DLH PF01738.13 KKK27112.1 - 4.9e-07 29.2 0.0 1e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 Dienelactone hydrolase family PMP1_2 PF08114.6 KKK27114.1 - 1.3 8.5 7.7 0.93 9.0 0.7 2.8 2 0 0 2 2 2 0 ATPase proteolipid family Pyr_redox_3 PF13738.1 KKK27115.1 - 9.4e-19 68.2 0.0 1.9e-18 67.2 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KKK27115.1 - 2.2e-11 43.3 0.0 5.3e-10 38.7 0.0 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 KKK27115.1 - 2.9e-09 37.0 0.0 6.7e-09 35.9 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KKK27115.1 - 1.8e-08 33.0 0.0 2.9e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 KKK27115.1 - 0.00063 19.7 0.0 0.0018 18.2 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 KKK27115.1 - 0.016 15.0 0.2 0.13 12.0 0.0 2.4 2 1 0 2 2 2 0 FAD-NAD(P)-binding Thi4 PF01946.12 KKK27115.1 - 0.06 12.4 0.1 0.14 11.2 0.0 1.6 1 0 0 1 1 1 0 Thi4 family CrtC PF07143.6 KKK27116.1 - 1.7e-09 37.4 0.1 2.2e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 Hydroxyneurosporene synthase (CrtC) zf-C2H2_4 PF13894.1 KKK27117.1 - 2.2e-09 36.9 8.1 5e-05 23.3 0.2 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KKK27117.1 - 8.7e-09 35.2 11.7 9.7e-07 28.7 1.9 2.9 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.21 KKK27117.1 - 3.8e-08 33.2 12.9 1e-05 25.5 1.2 3.0 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 KKK27117.1 - 0.0014 18.7 3.4 0.02 15.0 0.1 2.3 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-BED PF02892.10 KKK27117.1 - 0.04 13.6 0.4 0.04 13.6 0.3 2.2 2 0 0 2 2 2 0 BED zinc finger zf-C2H2_6 PF13912.1 KKK27117.1 - 0.056 13.3 3.8 2.2 8.3 0.1 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger DUF3295 PF11702.3 KKK27118.1 - 1.1e-197 658.1 32.2 1.2e-197 657.9 22.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3295) DUF1752 PF08550.5 KKK27118.1 - 5e-12 45.1 2.4 1.2e-11 43.9 1.7 1.7 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) DUF1479 PF07350.7 KKK27119.1 - 8.5e-169 561.4 0.0 9.8e-169 561.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) DUF1620 PF07774.8 KKK27120.1 - 1e-75 253.7 0.0 2.5e-75 252.4 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1620) PQQ_2 PF13360.1 KKK27120.1 - 1.9e-22 79.9 14.1 2.2e-19 69.8 1.6 3.2 2 1 0 2 2 2 2 PQQ-like domain PQQ PF01011.16 KKK27120.1 - 5.5e-09 35.1 4.7 0.073 12.6 0.0 6.0 6 0 0 6 6 6 3 PQQ enzyme repeat PQQ_3 PF13570.1 KKK27120.1 - 0.027 14.7 4.1 0.56 10.5 0.0 4.4 4 1 0 4 4 4 0 PQQ-like domain EXS PF03124.9 KKK27121.1 - 4e-95 318.7 31.4 5.1e-95 318.4 21.8 1.1 1 0 0 1 1 1 1 EXS family SPX PF03105.14 KKK27121.1 - 1.6e-66 224.9 1.4 2.6e-66 224.2 1.0 1.4 1 0 0 1 1 1 1 SPX domain Rad60-SLD_2 PF13881.1 KKK27122.1 - 2.8e-12 46.5 0.0 4.7e-12 45.7 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 KKK27122.1 - 0.0015 17.8 0.0 0.0029 16.9 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.4 KKK27122.1 - 0.0032 17.6 0.0 0.0057 16.8 0.0 1.4 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain UMP1 PF05348.6 KKK27123.1 - 2.3e-20 72.8 0.0 3.7e-20 72.2 0.0 1.3 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 Ribosom_S12_S23 PF00164.20 KKK27124.1 - 3.5e-41 139.4 1.1 4.7e-41 139.0 0.8 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 adh_short PF00106.20 KKK27125.1 - 6e-17 62.0 0.2 6.8e-16 58.6 0.1 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KKK27125.1 - 2.8e-09 37.1 0.0 6.1e-09 36.0 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KKK27125.1 - 7.6e-06 25.7 0.0 0.00039 20.1 0.0 2.1 2 0 0 2 2 2 1 KR domain DUF1776 PF08643.5 KKK27125.1 - 0.075 12.1 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Aa_trans PF01490.13 KKK27126.1 - 6.6e-96 321.2 14.8 6.6e-96 321.2 10.3 1.4 2 0 0 2 2 2 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 KKK27126.1 - 4e-05 22.6 17.7 4e-05 22.6 12.3 1.7 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family Bax1-I PF01027.15 KKK27127.1 - 2e-48 164.7 31.7 2.3e-48 164.5 22.0 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Orbi_NS3 PF01616.11 KKK27127.1 - 0.025 13.5 2.1 0.089 11.7 0.2 2.3 2 0 0 2 2 2 0 Orbivirus NS3 SNF2_N PF00176.18 KKK27128.1 - 2.4e-50 171.0 0.0 4.1e-50 170.2 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KKK27128.1 - 3.2e-06 26.9 0.0 7.7e-06 25.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_3 PF13920.1 KKK27128.1 - 2.6e-05 23.7 5.4 5e-05 22.8 3.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KKK27128.1 - 5.6e-05 23.0 8.4 0.00014 21.8 5.9 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KKK27128.1 - 0.00079 19.1 8.2 0.0019 17.8 5.7 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KKK27128.1 - 0.049 13.2 10.0 0.12 12.0 7.0 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KKK27128.1 - 0.073 12.9 7.2 0.18 11.6 5.0 1.7 1 0 0 1 1 1 0 Ring finger domain Prok-RING_4 PF14447.1 KKK27128.1 - 0.092 12.3 2.0 0.24 10.9 1.4 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Ribosomal_S30AE PF02482.14 KKK27128.1 - 0.096 13.1 3.1 0.28 11.6 2.1 1.8 1 0 0 1 1 1 0 Sigma 54 modulation protein / S30EA ribosomal protein Sod_Cu PF00080.15 KKK27129.1 - 6.4e-45 152.7 3.2 7.5e-45 152.5 2.2 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Chlorovi_GP_rpt PF06598.6 KKK27129.1 - 0.3 10.9 2.9 1 9.2 0.2 2.4 2 0 0 2 2 2 0 Chlorovirus glycoprotein repeat SNase PF00565.12 KKK27130.1 - 2.2e-75 249.8 0.0 1.6e-24 86.2 0.0 5.7 5 0 0 5 5 5 5 Staphylococcal nuclease homologue CRAL_TRIO PF00650.15 KKK27130.1 - 1.7e-24 86.1 0.0 2.9e-24 85.3 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain TUDOR PF00567.19 KKK27130.1 - 9.9e-24 83.5 0.0 2.4e-23 82.2 0.0 1.7 1 0 0 1 1 1 1 Tudor domain CRAL_TRIO_N PF03765.10 KKK27130.1 - 1.8e-09 37.5 0.1 4.8e-09 36.2 0.1 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain SMN PF06003.7 KKK27130.1 - 0.001 18.2 0.0 0.0022 17.1 0.0 1.5 1 0 0 1 1 1 1 Survival motor neuron protein (SMN) Beach PF02138.13 KKK27131.1 - 6.6e-110 366.7 0.1 2.4e-109 364.9 0.0 2.0 2 1 0 2 2 2 1 Beige/BEACH domain PH_BEACH PF14844.1 KKK27131.1 - 4.9e-13 48.8 0.0 1.3e-12 47.4 0.0 1.7 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH WD40 PF00400.27 KKK27131.1 - 1.7e-09 37.1 0.9 0.0021 17.9 0.2 3.5 3 0 0 3 3 3 2 WD domain, G-beta repeat Laminin_G_3 PF13385.1 KKK27131.1 - 2.8e-07 30.8 0.0 6.4e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Transaldolase PF00923.14 KKK27132.1 - 4e-95 318.2 0.2 4.6e-95 318.0 0.1 1.0 1 0 0 1 1 1 1 Transaldolase UQ_con PF00179.21 KKK27133.1 - 6.6e-40 135.7 0.0 8.2e-40 135.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KKK27133.1 - 0.097 12.4 0.1 0.42 10.3 0.1 1.9 1 1 0 1 1 1 0 Prokaryotic E2 family B RWD PF05773.17 KKK27133.1 - 0.12 12.2 1.1 0.26 11.1 0.7 1.6 1 1 0 1 1 1 0 RWD domain TRAP_alpha PF03896.11 KKK27133.1 - 0.24 10.3 4.1 0.39 9.6 2.8 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Peptidase_S8 PF00082.17 KKK27134.1 - 1.6e-56 191.5 8.4 2.3e-56 191.0 5.8 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 KKK27134.1 - 1.2e-17 64.2 0.4 6.2e-17 61.9 0.1 2.1 2 0 0 2 2 2 1 Peptidase inhibitor I9 Ferritin_2 PF13668.1 KKK27135.1 - 7.1e-10 38.9 0.0 1e-09 38.4 0.0 1.2 1 0 0 1 1 1 1 Ferritin-like domain ABC_tran PF00005.22 KKK27136.1 - 8.7e-54 181.5 0.0 3.2e-31 108.4 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 KKK27136.1 - 8.4e-46 156.5 28.0 1.8e-26 93.1 2.7 3.9 4 1 0 4 4 4 3 ABC transporter transmembrane region SMC_N PF02463.14 KKK27136.1 - 5.6e-08 32.2 0.0 0.0013 18.0 0.0 3.8 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KKK27136.1 - 5.1e-07 29.9 9.5 0.042 13.8 0.0 4.5 5 1 1 6 6 4 2 AAA domain AAA_25 PF13481.1 KKK27136.1 - 8.5e-07 28.5 0.0 0.018 14.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.1 KKK27136.1 - 3.4e-05 24.2 7.4 0.00041 20.7 0.1 3.1 3 1 0 3 3 2 1 AAA domain AAA_16 PF13191.1 KKK27136.1 - 0.00028 20.9 0.2 1.2 9.1 0.0 2.8 2 1 0 2 2 2 2 AAA ATPase domain DUF258 PF03193.11 KKK27136.1 - 0.00029 20.0 0.2 0.19 10.9 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 KKK27136.1 - 0.00039 20.3 0.0 0.14 12.1 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_29 PF13555.1 KKK27136.1 - 0.00058 19.3 0.2 1 8.9 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_10 PF12846.2 KKK27136.1 - 0.0007 19.1 0.5 0.16 11.3 0.0 3.0 3 0 0 3 3 3 1 AAA-like domain Miro PF08477.8 KKK27136.1 - 0.0008 19.8 0.1 2.4 8.6 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein T2SE PF00437.15 KKK27136.1 - 0.0017 17.3 0.0 0.083 11.7 0.0 2.2 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_22 PF13401.1 KKK27136.1 - 0.0021 18.1 1.4 7.3 6.7 0.1 3.5 2 1 0 2 2 2 0 AAA domain AAA_17 PF13207.1 KKK27136.1 - 0.0022 18.7 0.3 3.3 8.5 0.1 3.1 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 KKK27136.1 - 0.0026 16.8 4.4 0.16 11.0 0.1 2.5 3 0 0 3 3 2 2 Zeta toxin DUF87 PF01935.12 KKK27136.1 - 0.0036 17.1 2.3 0.029 14.1 0.1 2.9 3 0 0 3 3 3 1 Domain of unknown function DUF87 IstB_IS21 PF01695.12 KKK27136.1 - 0.0049 16.3 0.2 2.2 7.6 0.0 2.9 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_18 PF13238.1 KKK27136.1 - 0.0058 16.9 1.0 7 6.9 0.0 3.4 3 0 0 3 3 3 0 AAA domain AAA PF00004.24 KKK27136.1 - 0.0067 16.6 1.0 0.58 10.3 0.1 3.2 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) ATP-synt_ab PF00006.20 KKK27136.1 - 0.024 14.1 0.2 5.7 6.3 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain MobB PF03205.9 KKK27136.1 - 0.066 12.9 0.1 14 5.3 0.0 2.8 3 0 0 3 3 2 0 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 KKK27136.1 - 0.1 12.7 0.1 19 5.4 0.0 2.8 2 0 0 2 2 2 0 RNA helicase AAA_14 PF13173.1 KKK27136.1 - 0.14 12.0 0.3 4.3 7.2 0.1 2.9 2 0 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.4 KKK27136.1 - 0.21 10.1 1.9 1.7 7.2 0.1 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain NACHT PF05729.7 KKK27136.1 - 0.27 10.8 2.1 2.3 7.8 0.1 2.4 2 0 0 2 2 2 0 NACHT domain Arch_ATPase PF01637.13 KKK27136.1 - 0.76 9.4 3.7 0.31 10.6 0.0 2.2 3 0 0 3 3 2 0 Archaeal ATPase PAT1 PF09770.4 KKK27137.1 - 4.1e-290 964.7 11.8 4.6e-290 964.5 8.2 1.0 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Glyco_transf_15 PF01793.11 KKK27138.1 - 1.4e-137 458.1 8.6 1.7e-137 457.8 6.0 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase SUV3_C PF12513.3 KKK27139.1 - 1.2e-15 56.6 0.0 2.5e-15 55.6 0.0 1.6 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.26 KKK27139.1 - 3.4e-10 39.6 0.0 1.3e-09 37.7 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain TK PF00265.13 KKK27139.1 - 0.087 12.3 0.0 0.23 10.9 0.0 1.7 1 0 0 1 1 1 0 Thymidine kinase Sec1 PF00995.18 KKK27140.1 - 2.5e-134 449.0 0.0 2.9e-134 448.8 0.0 1.0 1 0 0 1 1 1 1 Sec1 family DUF1180 PF06679.7 KKK27140.1 - 0.75 9.6 3.5 1.5 8.7 2.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) G-patch PF01585.18 KKK27141.1 - 1.1e-05 25.0 0.2 2.3e-05 24.0 0.1 1.5 1 0 0 1 1 1 1 G-patch domain zf-U1 PF06220.7 KKK27141.1 - 0.21 11.1 1.9 12 5.5 0.1 2.4 2 0 0 2 2 2 0 U1 zinc finger adh_short PF00106.20 KKK27142.1 - 1.7e-11 44.3 0.0 2.9e-11 43.5 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KKK27142.1 - 6.1e-08 32.5 0.0 1.1e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KKK27142.1 - 0.00054 19.8 0.0 0.00084 19.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 KKK27142.1 - 0.016 15.2 0.1 0.028 14.4 0.1 1.4 1 0 0 1 1 1 0 NADH(P)-binding Polysacc_synt_2 PF02719.10 KKK27142.1 - 0.036 12.9 0.1 0.05 12.4 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NmrA PF05368.8 KKK27142.1 - 0.14 11.4 0.0 0.23 10.6 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family Epimerase PF01370.16 KKK27143.1 - 2.3e-47 161.3 0.0 3.1e-47 160.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Epimerase_Csub PF13950.1 KKK27143.1 - 2.8e-26 91.2 0.1 5.2e-26 90.3 0.1 1.5 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit 3Beta_HSD PF01073.14 KKK27143.1 - 3.3e-16 58.8 0.0 4.9e-16 58.2 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 KKK27143.1 - 1e-12 48.2 0.1 1.8e-12 47.4 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.12 KKK27143.1 - 1.2e-12 47.3 0.0 1.9e-12 46.6 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 KKK27143.1 - 5.8e-12 45.1 0.0 8.6e-11 41.2 0.0 2.2 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 KKK27143.1 - 1.1e-08 35.2 0.0 1.8e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding KR PF08659.5 KKK27143.1 - 3.7e-08 33.2 0.1 8.6e-08 32.0 0.0 1.6 1 1 0 1 1 1 1 KR domain NAD_binding_4 PF07993.7 KKK27143.1 - 7.4e-07 28.3 0.0 4.1e-05 22.6 0.0 2.2 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.8 KKK27143.1 - 0.0016 17.7 0.0 0.014 14.6 0.0 2.0 2 0 0 2 2 2 1 NmrA-like family 3HCDH_N PF02737.13 KKK27143.1 - 0.038 13.6 0.0 0.059 13.0 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 KKK27143.1 - 0.047 13.0 0.1 0.084 12.2 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Cys_Met_Meta_PP PF01053.15 KKK27143.1 - 0.053 11.8 0.1 0.31 9.2 0.0 2.0 2 0 0 2 2 2 0 Cys/Met metabolism PLP-dependent enzyme Sugar_tr PF00083.19 KKK27144.1 - 3.4e-74 250.0 18.7 1.8e-73 247.6 13.0 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KKK27144.1 - 6.8e-22 77.6 11.6 2.4e-20 72.5 6.9 2.3 2 1 0 2 2 2 2 Major Facilitator Superfamily Ribosomal_L44 PF00935.14 KKK27145.1 - 3.1e-34 116.8 12.0 5.8e-34 115.9 8.3 1.5 1 0 0 1 1 1 1 Ribosomal protein L44 TBCA PF02970.11 KKK27146.1 - 1.8e-23 82.3 9.2 2.3e-23 82.0 6.4 1.1 1 0 0 1 1 1 1 Tubulin binding cofactor A Mnd1 PF03962.10 KKK27146.1 - 0.07 12.7 6.7 0.082 12.5 4.6 1.1 1 0 0 1 1 1 0 Mnd1 family GLYCAM-1 PF05242.6 KKK27146.1 - 0.23 11.3 2.9 0.28 11.0 2.0 1.2 1 0 0 1 1 1 0 Glycosylation-dependent cell adhesion molecule 1 (GlyCAM-1) Ead_Ea22 PF13935.1 KKK27146.1 - 0.34 11.2 4.7 0.42 10.9 3.3 1.2 1 0 0 1 1 1 0 Ead/Ea22-like protein HABP4_PAI-RBP1 PF04774.10 KKK27146.1 - 1.3 9.5 5.6 0.3 11.6 1.3 1.7 1 1 1 2 2 2 0 Hyaluronan / mRNA binding family IncA PF04156.9 KKK27146.1 - 1.6 8.3 9.6 1.9 8.0 6.7 1.1 1 0 0 1 1 1 0 IncA protein THOC7 PF05615.8 KKK27147.1 - 8.5e-40 136.2 5.7 8.5e-40 136.2 4.0 2.0 1 1 1 2 2 2 1 Tho complex subunit 7 SSFA2_C PF14723.1 KKK27147.1 - 0.017 14.8 3.7 0.017 14.8 2.6 1.7 2 0 0 2 2 2 0 Sperm-specific antigen 2 C-terminus zf-C4H2 PF10146.4 KKK27147.1 - 0.026 14.5 10.9 0.067 13.2 4.0 2.4 1 1 2 3 3 3 0 Zinc finger-containing protein DUF4600 PF15372.1 KKK27147.1 - 0.089 13.0 9.0 0.19 11.9 6.2 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4600) DUF342 PF03961.8 KKK27147.1 - 0.16 10.3 2.6 0.23 9.8 1.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) AAA_23 PF13476.1 KKK27147.1 - 0.18 12.1 5.0 0.37 11.0 3.4 1.6 1 0 0 1 1 1 0 AAA domain DUF1843 PF08898.5 KKK27147.1 - 0.87 9.6 4.8 2.3 8.3 1.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF1843) DivIC PF04977.10 KKK27147.1 - 2.6 7.5 8.7 0.6 9.6 2.3 2.7 1 1 1 2 2 2 0 Septum formation initiator FUSC PF04632.7 KKK27147.1 - 3.3 6.0 5.3 3.9 5.8 3.7 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Elongin_A PF06881.6 KKK27148.1 - 1.1e-31 109.3 0.2 2.1e-31 108.5 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A Toxin_51 PF15531.1 KKK27148.1 - 0.13 12.0 0.0 4.3 7.1 0.0 2.3 2 0 0 2 2 2 0 Putative toxin 51 Band_7 PF01145.20 KKK27149.1 - 1.3e-13 51.2 0.1 1.3e-13 51.2 0.1 2.3 2 0 0 2 2 2 1 SPFH domain / Band 7 family DBD_Tnp_Mut PF03108.10 KKK27150.1 - 1.5e-13 50.0 0.2 2.7e-13 49.2 0.1 1.4 1 0 0 1 1 1 1 MuDR family transposase Fungal_trans PF04082.13 KKK27151.1 - 2.2e-06 26.7 0.6 7.5e-06 24.9 0.1 1.9 1 1 1 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK27151.1 - 0.0024 17.7 2.5 0.0046 16.8 1.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sel1 PF08238.7 KKK27152.1 - 9.3e-36 121.4 50.7 1.7e-07 31.6 0.1 8.4 9 1 0 9 9 9 7 Sel1 repeat TPR_20 PF14561.1 KKK27152.1 - 0.035 14.2 0.7 1.9 8.6 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.1 KKK27152.1 - 0.037 14.2 0.2 0.98 9.7 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat AAA_12 PF13087.1 KKK27153.1 - 7.3e-39 133.2 0.0 1.2e-38 132.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KKK27153.1 - 2.7e-07 30.4 0.0 3.5e-06 26.7 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KKK27153.1 - 5.7e-05 22.7 0.0 0.00054 19.6 0.0 2.4 2 0 0 2 2 2 1 Part of AAA domain KaiC PF06745.8 KKK27153.1 - 0.048 12.7 0.0 0.083 11.9 0.0 1.3 1 0 0 1 1 1 0 KaiC DUF2075 PF09848.4 KKK27153.1 - 0.063 12.2 0.0 0.13 11.2 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Viral_helicase1 PF01443.13 KKK27153.1 - 0.081 12.4 0.3 33 3.8 0.0 3.7 4 1 1 5 5 5 0 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.1 KKK27153.1 - 0.36 10.3 0.0 3.6 7.1 0.0 2.3 2 1 0 2 2 2 0 AAA domain FAD_binding_3 PF01494.14 KKK27154.1 - 2.2e-73 247.3 0.4 2e-72 244.1 0.3 2.0 1 1 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 KKK27154.1 - 2.1e-25 89.2 0.0 3.9e-25 88.4 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain SE PF08491.5 KKK27154.1 - 0.0055 15.5 0.0 0.02 13.7 0.0 1.8 2 0 0 2 2 2 1 Squalene epoxidase Pyr_redox_2 PF07992.9 KKK27154.1 - 0.038 13.8 0.0 0.39 10.5 0.0 2.2 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KKK27154.1 - 0.064 12.1 1.9 0.3 9.9 0.0 2.1 1 1 0 2 2 2 0 FAD dependent oxidoreductase HI0933_like PF03486.9 KKK27154.1 - 0.099 11.0 0.0 0.15 10.4 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Lycopene_cycl PF05834.7 KKK27154.1 - 0.1 11.4 0.1 0.17 10.7 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_3 PF13738.1 KKK27155.1 - 2.6e-19 70.1 0.0 9.9e-19 68.2 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KKK27155.1 - 4.5e-12 44.9 3.3 1.5e-11 43.2 0.7 2.5 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 KKK27155.1 - 2.9e-11 43.2 0.0 5.8e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KKK27155.1 - 1.7e-09 37.8 0.0 2.9e-08 33.8 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KKK27155.1 - 1.5e-07 30.7 0.6 2.9e-05 23.1 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 KKK27155.1 - 5e-05 22.3 0.0 0.0012 17.7 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KKK27155.1 - 0.00091 19.0 1.5 0.0038 17.0 0.0 2.7 4 0 0 4 4 4 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 KKK27155.1 - 0.0023 16.9 0.1 0.0036 16.2 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.12 KKK27155.1 - 0.021 13.9 2.2 0.23 10.5 0.0 2.5 3 0 0 3 3 3 0 Thi4 family DUF498 PF04430.9 KKK27155.1 - 0.087 12.3 0.0 8.7 5.9 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF498/DUF598) FAD_binding_2 PF00890.19 KKK27155.1 - 0.16 10.8 0.0 0.25 10.1 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain MPC PF03650.8 KKK27156.1 - 9.1e-45 151.4 0.2 1.2e-44 151.0 0.1 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) MFS_1 PF07690.11 KKK27157.1 - 9.1e-43 146.3 23.4 9.1e-43 146.3 16.2 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KKK27157.1 - 7.4e-16 57.7 11.4 1.1e-15 57.2 7.9 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter Fungal_trans PF04082.13 KKK27158.1 - 8.6e-13 47.7 2.4 1.5e-12 46.9 1.6 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2_4 PF13894.1 KKK27158.1 - 0.012 15.8 4.3 0.012 15.8 3.0 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.21 KKK27158.1 - 0.046 14.0 4.1 0.17 12.2 2.9 2.1 1 0 0 1 1 1 0 Zinc finger, C2H2 type Glyco_hydro_28 PF00295.12 KKK27159.1 - 8e-49 166.3 6.7 1.3e-48 165.6 4.7 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.1 KKK27159.1 - 0.42 10.3 16.3 1.1 9.0 9.9 2.2 1 1 1 2 2 2 0 Right handed beta helix region LigB PF02900.13 KKK27160.1 - 1.9e-46 158.2 0.0 2.2e-46 158.0 0.0 1.0 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase Herpes_ORF11 PF04797.8 KKK27160.1 - 0.16 10.4 0.0 0.24 9.7 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus dUTPase protein L51_S25_CI-B8 PF05047.11 KKK27161.1 - 4.8e-10 39.0 0.0 6e-10 38.7 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain CBP4 PF07960.6 KKK27162.1 - 4.4e-38 129.7 1.4 5.6e-38 129.4 0.9 1.0 1 0 0 1 1 1 1 CBP4 Ank_2 PF12796.2 KKK27163.1 - 1.4e-164 534.8 5.1 1.5e-15 57.2 0.0 11.7 2 2 10 12 12 12 12 Ankyrin repeats (3 copies) Ank PF00023.25 KKK27163.1 - 5.1e-146 467.8 1.3 7.8e-08 31.7 0.0 23.2 23 0 0 23 23 23 23 Ankyrin repeat Ank_4 PF13637.1 KKK27163.1 - 6.6e-120 389.6 5.5 2.9e-13 49.9 0.0 17.6 3 2 16 20 20 20 20 Ankyrin repeats (many copies) Ank_5 PF13857.1 KKK27163.1 - 4e-99 322.4 18.0 4e-12 45.9 0.0 17.2 6 3 13 19 19 19 19 Ankyrin repeats (many copies) Ank_3 PF13606.1 KKK27163.1 - 1.1e-98 313.0 0.1 2.2e-05 24.2 0.0 23.2 23 0 0 23 23 23 19 Ankyrin repeat Shigella_OspC PF06128.6 KKK27163.1 - 0.00031 20.3 0.5 38 3.6 0.0 7.1 5 3 3 9 9 9 0 Shigella flexneri OspC protein DUF3718 PF12514.3 KKK27163.1 - 0.11 12.5 0.1 2.9 8.0 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3718) Synaptobrevin PF00957.16 KKK27164.1 - 1e-31 108.3 0.7 1.2e-31 108.1 0.5 1.0 1 0 0 1 1 1 1 Synaptobrevin Prominin PF05478.6 KKK27164.1 - 0.023 12.2 0.0 0.03 11.8 0.0 1.1 1 0 0 1 1 1 0 Prominin PRT_C PF08372.5 KKK27164.1 - 0.17 11.3 2.0 0.36 10.3 1.3 1.5 1 1 0 1 1 1 0 Plant phosphoribosyltransferase C-terminal DUF1035 PF06281.7 KKK27164.1 - 0.93 9.3 3.8 1.5 8.6 2.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1035) DUF619 PF04768.8 KKK27165.1 - 7.6e-54 181.6 0.1 1.6e-53 180.6 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF619) Semialdhyde_dh PF01118.19 KKK27165.1 - 1.2e-29 103.1 0.0 3.1e-29 101.7 0.0 1.8 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain AA_kinase PF00696.23 KKK27165.1 - 6e-25 88.1 0.0 1.1e-24 87.3 0.0 1.4 1 0 0 1 1 1 1 Amino acid kinase family DapB_N PF01113.15 KKK27165.1 - 0.031 14.1 0.0 0.11 12.4 0.0 2.0 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus PDH PF02153.12 KKK27166.1 - 1.7e-13 50.0 0.0 2.4e-13 49.5 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydrogenase F420_oxidored PF03807.12 KKK27166.1 - 7.4e-07 29.5 0.0 1.4e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 KKK27166.1 - 3.3e-06 27.0 0.0 5.4e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.14 KKK27166.1 - 0.0016 17.6 0.0 0.003 16.7 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.11 KKK27166.1 - 0.005 16.2 0.0 0.0091 15.4 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.13 KKK27166.1 - 0.017 14.8 0.0 0.034 13.8 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.13 KKK27166.1 - 0.049 13.6 0.1 0.2 11.6 0.0 2.0 2 0 0 2 2 2 0 TrkA-N domain DUF4168 PF13767.1 KKK27166.1 - 0.072 13.7 0.1 23 5.6 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4168) IlvN PF07991.7 KKK27166.1 - 0.13 11.6 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain Ribosomal_S11 PF00411.14 KKK27167.1 - 8.2e-24 83.9 0.1 1e-23 83.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 RICTOR_N PF14664.1 KKK27168.1 - 7.6e-139 462.4 1.0 1.9e-138 461.1 0.6 1.7 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, N-term RICTOR_M PF14666.1 KKK27168.1 - 5.9e-89 296.9 0.4 4.7e-87 290.7 0.1 3.4 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR, middle domain RasGEF_N_2 PF14663.1 KKK27168.1 - 1.9e-44 150.3 0.0 1.8e-42 143.9 0.0 3.2 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.1 KKK27168.1 - 1.9e-24 85.4 4.1 1.4e-23 82.5 0.1 3.9 5 0 0 5 5 5 1 Rapamycin-insensitive companion of mTOR, domain 5 HR1 PF02185.11 KKK27168.1 - 3.2e-14 52.4 4.1 7.2e-14 51.2 2.8 1.7 1 0 0 1 1 1 1 Hr1 repeat Uds1 PF15456.1 KKK27168.1 - 0.0034 17.3 5.6 0.0092 15.9 3.9 1.7 1 0 0 1 1 1 1 Up-regulated During Septation PsiA PF06952.6 KKK27168.1 - 0.027 13.5 0.0 0.047 12.7 0.0 1.3 1 0 0 1 1 1 0 PsiA protein Arm PF00514.18 KKK27168.1 - 0.58 10.0 4.3 16 5.5 0.1 3.4 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat Cytochrom_B561 PF03188.11 KKK27169.1 - 2.7e-05 24.0 5.2 2.7e-05 24.0 3.6 1.6 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 EST1_DNA_bind PF10373.4 KKK27170.1 - 2.1e-65 220.7 0.1 3.4e-65 220.0 0.1 1.3 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain EST1 PF10374.4 KKK27170.1 - 8.7e-23 80.7 0.1 1.8e-22 79.7 0.1 1.5 1 0 0 1 1 1 1 Telomerase activating protein Est1 TPR_11 PF13414.1 KKK27170.1 - 0.00019 20.9 0.3 0.00045 19.8 0.2 1.5 1 0 0 1 1 1 1 TPR repeat DUF1649 PF07855.7 KKK27171.1 - 4.7e-64 214.9 0.0 5.5e-64 214.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1649) PfkB PF00294.19 KKK27172.1 - 7.2e-68 228.9 0.1 8.3e-68 228.7 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 KKK27172.1 - 0.0017 17.5 0.0 0.0035 16.5 0.0 1.5 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase Peroxin-3 PF04882.7 KKK27173.1 - 1.9e-143 478.2 0.0 2.3e-143 478.0 0.0 1.0 1 0 0 1 1 1 1 Peroxin-3 MFS_1 PF07690.11 KKK27174.1 - 1.8e-35 122.2 29.6 1.8e-35 122.2 20.5 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.2 KKK27174.1 - 0.12 12.2 4.9 0.063 13.0 1.0 2.4 2 0 0 2 2 2 0 MFS_1 like family TB2_DP1_HVA22 PF03134.14 KKK27175.1 - 2e-30 104.3 6.9 2.7e-30 103.9 4.8 1.2 1 0 0 1 1 1 1 TB2/DP1, HVA22 family zf-C2H2 PF00096.21 KKK27176.1 - 1.8e-12 46.7 8.4 1.3e-05 25.2 1.8 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KKK27176.1 - 1.7e-09 37.3 8.4 0.00017 21.6 2.2 3.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KKK27176.1 - 7.2e-09 35.5 2.4 7.2e-09 35.5 1.6 3.5 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2HC_2 PF13913.1 KKK27176.1 - 0.00017 21.1 2.1 0.18 11.4 0.2 3.0 2 0 0 2 2 2 2 zinc-finger of a C2HC-type zf-C2H2_jaz PF12171.3 KKK27176.1 - 0.0052 16.8 10.2 0.076 13.1 0.6 2.8 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KKK27176.1 - 0.0053 16.9 3.8 0.69 10.1 0.5 2.8 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 KKK27176.1 - 0.0098 15.7 4.2 1.5 8.8 0.0 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-BED PF02892.10 KKK27176.1 - 4.7 7.0 6.4 6.1 6.6 1.3 2.9 2 1 1 3 3 3 0 BED zinc finger zf-C2H2_4 PF13894.1 KKK27177.1 - 0.0028 17.8 3.7 0.28 11.6 0.2 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KKK27177.1 - 0.045 14.1 0.3 0.045 14.1 0.2 2.9 3 0 0 3 3 3 0 Zinc finger, C2H2 type Pkinase PF00069.20 KKK27178.1 - 1.3e-67 227.7 0.0 2.8e-66 223.3 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KKK27178.1 - 1.3e-49 168.6 0.0 7.9e-48 162.7 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Ras_bdg_2 PF14847.1 KKK27178.1 - 6.7e-32 109.5 0.0 1.3e-31 108.6 0.0 1.5 1 0 0 1 1 1 1 Ras-binding domain of Byr2 SAM_1 PF00536.25 KKK27178.1 - 3.4e-14 52.7 0.1 8.8e-14 51.4 0.0 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 KKK27178.1 - 6.8e-12 45.0 0.1 1.7e-11 43.7 0.1 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Kinase-like PF14531.1 KKK27178.1 - 2.4e-08 33.3 0.0 7.8e-05 21.7 0.0 2.7 3 0 0 3 3 3 2 Kinase-like RA PF00788.18 KKK27178.1 - 6.2e-07 29.8 0.0 1.2e-06 28.9 0.0 1.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Kdo PF06293.9 KKK27178.1 - 0.021 13.9 0.0 0.046 12.7 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF2019 PF09450.5 KKK27178.1 - 0.067 13.0 0.3 0.18 11.6 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF2019) Seadorna_VP7 PF07387.6 KKK27178.1 - 0.15 10.8 0.0 0.32 9.7 0.0 1.5 1 0 0 1 1 1 0 Seadornavirus VP7 SNF2_N PF00176.18 KKK27179.1 - 4.5e-84 281.7 1.0 4.5e-84 281.7 0.7 2.2 2 0 0 2 2 2 1 SNF2 family N-terminal domain Bromodomain PF00439.20 KKK27179.1 - 2.8e-25 88.0 2.6 3.6e-24 84.4 0.1 3.1 3 0 0 3 3 3 1 Bromodomain SnAC PF14619.1 KKK27179.1 - 4e-19 68.5 4.1 4e-19 68.5 2.9 3.6 3 1 0 3 3 3 1 Snf2-ATP coupling, chromatin remodelling complex Helicase_C PF00271.26 KKK27179.1 - 1.6e-17 63.1 0.1 4e-16 58.6 0.0 3.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain HSA PF07529.8 KKK27179.1 - 2.4e-16 59.2 15.8 2.4e-16 59.2 11.0 2.6 2 0 0 2 2 2 1 HSA QLQ PF08880.6 KKK27179.1 - 3.4e-14 51.9 1.5 1e-13 50.4 1.1 1.9 1 0 0 1 1 1 1 QLQ M11L PF11099.3 KKK27179.1 - 0.074 12.7 0.0 0.22 11.2 0.0 1.7 1 0 0 1 1 1 0 Apoptosis regulator M11L like BAR PF03114.13 KKK27180.1 - 3.9e-48 163.9 8.0 5.2e-48 163.5 5.5 1.1 1 0 0 1 1 1 1 BAR domain BAR_2 PF10455.4 KKK27180.1 - 1.5e-07 30.6 3.6 1.9e-07 30.3 2.5 1.2 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking PMEI PF04043.10 KKK27180.1 - 0.01 15.7 0.7 1.7 8.5 0.1 2.4 1 1 1 2 2 2 0 Plant invertase/pectin methylesterase inhibitor Apo-CIII PF05778.7 KKK27180.1 - 0.013 14.9 0.1 0.033 13.5 0.1 1.6 1 0 0 1 1 1 0 Apolipoprotein CIII (Apo-CIII) Stirrup PF09061.1 KKK27180.1 - 0.1 12.4 0.1 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 Stirrup DUF1925 PF09094.6 KKK27180.1 - 0.22 11.5 0.7 2.7 8.0 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1925) APG6 PF04111.7 KKK27180.1 - 0.89 8.5 7.6 1.5 7.7 5.2 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 Ada_Zn_binding PF02805.11 KKK27181.1 - 2e-29 100.9 5.3 3.6e-29 100.1 3.7 1.4 1 0 0 1 1 1 1 Metal binding domain of Ada HTH_AraC PF00165.18 KKK27181.1 - 4.4e-07 29.5 0.0 9.5e-07 28.4 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_18 PF12833.2 KKK27181.1 - 0.0019 18.2 0.0 0.0041 17.1 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain Ribosomal_L2_C PF03947.13 KKK27182.1 - 4.4e-29 100.9 5.6 5.4e-27 94.1 3.8 2.4 1 1 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 KKK27182.1 - 3e-14 52.7 0.1 5.6e-14 51.8 0.0 1.5 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain WHIM1 PF15612.1 KKK27183.1 - 0.00031 20.5 0.0 0.00072 19.3 0.0 1.6 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 WHIM2 PF15613.1 KKK27183.1 - 0.015 15.1 0.5 0.043 13.7 0.3 1.7 1 0 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 2 Myosin_HC-like PF07058.6 KKK27183.1 - 0.19 10.7 1.4 0.29 10.1 1.0 1.2 1 0 0 1 1 1 0 Myosin II heavy chain-like DUF1770 PF08589.5 KKK27184.1 - 3.1e-21 75.8 0.4 9e-21 74.3 0.2 1.7 2 0 0 2 2 2 1 Fungal protein of unknown function (DUF1770) Aminotran_1_2 PF00155.16 KKK27185.1 - 1.6e-05 24.0 0.0 2.1e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Period_C PF12114.3 KKK27185.1 - 2 7.9 10.4 2.5 7.6 7.2 1.2 1 0 0 1 1 1 0 Period protein 2/3C-terminal region RAP1 PF07218.6 KKK27185.1 - 7.6 4.4 14.0 9.5 4.1 9.7 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) ERG4_ERG24 PF01222.12 KKK27187.1 - 2.4e-154 514.0 5.8 2.8e-154 513.8 4.1 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 KKK27187.1 - 5.2e-07 29.1 0.2 1.4e-06 27.8 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Vps55 PF04133.9 KKK27187.1 - 0.0014 18.4 1.6 0.0054 16.4 1.1 2.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 A_deamin PF02137.13 KKK27188.1 - 2.4e-45 155.3 0.0 8.8e-44 150.2 0.0 2.2 1 1 0 1 1 1 1 Adenosine-deaminase (editase) domain SF3b10 PF07189.6 KKK27189.1 - 1.1e-35 121.3 0.0 1.2e-35 121.1 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) DUF3074 PF11274.3 KKK27190.1 - 4.2e-61 205.7 0.3 4.2e-61 205.7 0.2 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3074) FlaC_arch PF05377.6 KKK27190.1 - 1 9.3 3.1 18 5.3 0.1 3.0 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) EBP PF05241.7 KKK27191.1 - 0.00027 20.0 0.3 0.00027 20.0 0.2 2.6 2 1 1 3 3 3 1 Emopamil binding protein Fungal_trans PF04082.13 KKK27192.1 - 3.6e-26 91.6 0.0 6e-26 90.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KKK27192.1 - 3.8e-09 36.3 12.1 6e-09 35.6 8.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Man-6-P_recep PF02157.10 KKK27193.1 - 2.2e-10 40.0 0.0 3.1e-10 39.5 0.0 1.2 1 0 0 1 1 1 1 Mannose-6-phosphate receptor CIMR PF00878.13 KKK27193.1 - 7e-09 35.6 1.2 0.00035 20.3 0.1 2.4 2 1 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat ATG27 PF09451.5 KKK27193.1 - 0.00016 21.0 0.0 0.00082 18.6 0.0 2.0 2 1 0 2 2 2 1 Autophagy-related protein 27 Vps51 PF08700.6 KKK27194.1 - 1.1e-26 92.4 0.0 2.6e-26 91.2 0.0 1.7 2 0 0 2 2 2 1 Vps51/Vps67 COG5 PF10392.4 KKK27194.1 - 0.0011 18.9 0.0 0.0021 18.0 0.0 1.4 1 0 0 1 1 1 1 Golgi transport complex subunit 5 Sec5 PF15469.1 KKK27194.1 - 0.016 14.9 0.0 0.044 13.5 0.0 1.7 1 1 0 1 1 1 0 Exocyst complex component Sec5 THUMP PF02926.12 KKK27194.1 - 0.038 13.8 0.3 0.062 13.1 0.2 1.3 1 0 0 1 1 1 0 THUMP domain Dor1 PF04124.7 KKK27194.1 - 0.047 12.1 0.0 0.056 11.8 0.0 1.2 1 0 0 1 1 1 0 Dor1-like family Cellulase PF00150.13 KKK27195.1 - 5.3e-10 38.9 1.0 2.1e-08 33.7 0.5 2.7 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) DUF1767 PF08585.7 KKK27196.1 - 2.8e-19 69.1 0.2 4e-19 68.6 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1767) TPR_11 PF13414.1 KKK27197.1 - 1.1e-39 133.8 35.3 9.1e-05 22.0 0.1 12.6 13 1 1 14 14 12 10 TPR repeat TPR_16 PF13432.1 KKK27197.1 - 9.8e-26 89.8 36.6 2.1e-05 25.0 0.0 12.1 9 2 3 12 12 12 8 Tetratricopeptide repeat TPR_17 PF13431.1 KKK27197.1 - 4e-24 82.7 9.6 0.2 11.9 0.0 15.0 16 0 0 16 16 16 4 Tetratricopeptide repeat TPR_12 PF13424.1 KKK27197.1 - 1.9e-20 72.5 22.6 8e-08 32.1 0.3 10.7 7 3 2 10 10 9 3 Tetratricopeptide repeat TPR_14 PF13428.1 KKK27197.1 - 1.1e-19 69.1 33.9 0.094 13.4 0.0 16.0 15 6 5 20 20 16 5 Tetratricopeptide repeat TPR_1 PF00515.23 KKK27197.1 - 4.7e-18 63.9 30.5 0.014 14.9 0.0 14.6 16 2 1 17 17 17 5 Tetratricopeptide repeat TPR_2 PF07719.12 KKK27197.1 - 3.9e-17 60.7 51.7 0.062 13.2 0.1 15.5 19 0 0 19 19 16 7 Tetratricopeptide repeat TPR_19 PF14559.1 KKK27197.1 - 1.3e-16 60.6 11.9 0.014 15.7 0.0 10.2 7 2 3 10 10 10 3 Tetratricopeptide repeat TPR_8 PF13181.1 KKK27197.1 - 1.6e-14 52.5 14.4 0.13 12.1 0.1 12.1 11 1 1 12 12 12 3 Tetratricopeptide repeat TPR_7 PF13176.1 KKK27197.1 - 4.7e-07 29.1 21.5 0.0016 18.1 0.0 10.7 13 1 0 13 13 12 2 Tetratricopeptide repeat TPR_6 PF13174.1 KKK27197.1 - 1e-06 28.7 21.3 0.21 12.1 0.1 10.7 14 0 0 14 14 11 2 Tetratricopeptide repeat Apc3 PF12895.2 KKK27197.1 - 0.00012 22.1 16.9 0.02 15.0 0.0 7.1 5 3 5 10 10 10 1 Anaphase-promoting complex, cyclosome, subunit 3 Coatomer_E PF04733.9 KKK27197.1 - 0.0013 17.9 0.1 0.018 14.2 0.0 2.6 2 0 0 2 2 2 1 Coatomer epsilon subunit DUF2225 PF09986.4 KKK27197.1 - 0.0019 17.6 1.6 0.49 9.8 0.1 3.5 3 1 0 3 3 3 1 Uncharacterized protein conserved in bacteria (DUF2225) TPR_10 PF13374.1 KKK27197.1 - 0.0024 17.7 17.7 0.35 10.8 0.1 8.5 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_4 PF07721.9 KKK27197.1 - 0.069 13.6 9.6 29 5.4 0.0 6.5 6 0 0 6 6 6 0 Tetratricopeptide repeat zf-CCHC PF00098.18 KKK27198.1 - 1.9e-44 147.5 54.6 2.3e-07 30.3 0.6 7.2 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_3 PF13917.1 KKK27198.1 - 3.5e-09 36.2 39.5 0.0058 16.3 0.2 6.9 4 2 2 6 6 6 5 Zinc knuckle zf-CCHC_4 PF14392.1 KKK27198.1 - 3.1e-08 33.1 39.7 0.067 12.8 0.4 7.1 7 0 0 7 7 7 6 Zinc knuckle zf-CCHC_2 PF13696.1 KKK27198.1 - 0.068 12.6 0.2 0.068 12.6 0.2 7.1 3 2 4 7 7 7 0 Zinc knuckle zf-CCHC_6 PF15288.1 KKK27198.1 - 6 6.6 44.3 0.23 11.1 1.0 6.9 6 1 1 7 7 7 0 Zinc knuckle Sigma70_ner PF04546.8 KKK27199.1 - 0.23 11.0 3.5 3.3 7.2 1.1 2.1 2 0 0 2 2 2 0 Sigma-70, non-essential region Bd3614_N PF14442.1 KKK27199.1 - 0.3 11.0 9.5 1.1 9.2 6.0 2.2 2 1 0 2 2 2 0 Bd3614-like deaminase N-terminal RRP7 PF12923.2 KKK27200.1 - 8.3e-33 113.1 11.2 8.3e-33 113.1 7.7 2.4 2 1 0 2 2 2 1 Ribosomal RNA-processing protein 7 (RRP7) RRM_6 PF14259.1 KKK27200.1 - 0.055 13.4 0.3 0.57 10.1 0.0 2.6 3 0 0 3 3 3 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KKK27200.1 - 0.077 12.6 0.1 5.1 6.8 0.0 3.0 3 0 0 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Dak1_2 PF13684.1 KKK27200.1 - 0.18 10.7 3.7 0.83 8.5 0.1 2.3 1 1 0 2 2 2 0 Dihydroxyacetone kinase family bZIP_1 PF00170.16 KKK27200.1 - 2.1 8.3 16.5 0.88 9.5 1.1 3.0 2 0 0 2 2 2 0 bZIP transcription factor Rad51 PF08423.6 KKK27201.1 - 4.4e-125 415.7 0.0 6.1e-125 415.2 0.0 1.2 1 0 0 1 1 1 1 Rad51 RecA PF00154.16 KKK27201.1 - 8.1e-11 41.5 0.0 1e-10 41.2 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein HHH_5 PF14520.1 KKK27201.1 - 8.6e-11 41.8 0.9 1.3e-09 38.1 0.1 2.7 3 0 0 3 3 3 1 Helix-hairpin-helix domain AAA_25 PF13481.1 KKK27201.1 - 7.5e-10 38.5 0.0 1.1e-09 38.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 KKK27201.1 - 7.2e-08 31.8 0.0 1.8e-07 30.5 0.0 1.7 2 1 0 2 2 2 1 KaiC RNA_pol_A_CTD PF03118.10 KKK27201.1 - 0.071 12.5 0.1 0.16 11.4 0.1 1.6 1 0 0 1 1 1 0 Bacterial RNA polymerase, alpha chain C terminal domain DivIVA PF05103.8 KKK27202.1 - 0.0017 18.3 26.7 0.034 14.1 7.0 3.6 3 1 1 4 4 4 2 DivIVA protein Bacillus_HBL PF05791.6 KKK27202.1 - 8.1 5.7 7.2 3.7 6.8 1.1 2.8 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) IncA PF04156.9 KKK27202.1 - 8.7 5.8 32.2 7.3 6.1 0.1 3.2 1 1 2 3 3 3 0 IncA protein Methyltransf_16 PF10294.4 KKK27203.1 - 1.5e-16 60.3 0.1 5.8e-10 38.9 0.0 2.1 2 0 0 2 2 2 2 Putative methyltransferase Methyltransf_18 PF12847.2 KKK27203.1 - 1.1e-05 25.9 0.0 2.9e-05 24.6 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.8 KKK27203.1 - 0.00042 19.5 0.0 0.00068 18.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Met_10 PF02475.11 KKK27203.1 - 0.00099 18.7 0.0 0.0016 18.0 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_23 PF13489.1 KKK27203.1 - 0.0014 18.3 0.0 0.0022 17.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KKK27203.1 - 0.0016 17.8 0.0 0.0025 17.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.14 KKK27203.1 - 0.004 16.7 0.0 0.0065 16.0 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_26 PF13659.1 KKK27203.1 - 0.0048 16.9 0.0 0.0077 16.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KKK27203.1 - 0.0057 16.2 0.2 0.014 15.0 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 KKK27203.1 - 0.025 15.0 0.2 0.77 10.2 0.0 2.8 3 0 0 3 3 3 0 Methyltransferase domain DUF938 PF06080.7 KKK27203.1 - 0.029 13.8 0.0 0.05 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) RrnaAD PF00398.15 KKK27203.1 - 0.035 13.1 0.0 0.059 12.3 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Trypan_PARP PF05887.6 KKK27203.1 - 0.043 13.6 1.1 0.084 12.6 0.7 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Methyltransf_11 PF08241.7 KKK27203.1 - 0.1 13.0 0.0 0.2 12.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Pro_isomerase PF00160.16 KKK27204.1 - 9.9e-34 116.7 0.0 1.6e-33 116.1 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.17 KKK27204.1 - 4.4e-16 58.2 0.1 1e-15 57.1 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KKK27204.1 - 6.4e-12 45.2 0.0 1.5e-11 44.0 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KKK27204.1 - 1.6e-09 37.4 0.1 3.2e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KKK27204.1 - 0.15 11.8 0.0 0.35 10.6 0.0 1.6 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif UDPGP PF01704.13 KKK27205.1 - 2.2e-55 187.8 0.0 3.2e-55 187.3 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.2 KKK27205.1 - 0.0028 17.7 0.0 0.0095 16.0 0.0 1.9 2 0 0 2 2 2 1 MobA-like NTP transferase domain Ribosomal_S24e PF01282.14 KKK27206.1 - 8.5e-35 118.4 0.1 1.3e-34 117.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S24e Ribosomal_S3Ae PF01015.13 KKK27208.1 - 2.2e-06 27.1 0.5 2.9e-06 26.7 0.1 1.4 2 0 0 2 2 2 1 Ribosomal S3Ae family NAD_binding_6 PF08030.7 KKK27209.1 - 4e-07 30.0 0.0 0.00021 21.2 0.0 2.2 1 1 0 2 2 2 2 Ferric reductase NAD binding domain NAD_binding_1 PF00175.16 KKK27209.1 - 2.6e-06 27.9 0.0 0.049 14.1 0.0 2.4 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain Pantoate_ligase PF02569.10 KKK27209.1 - 0.018 13.8 0.0 0.026 13.3 0.0 1.1 1 0 0 1 1 1 0 Pantoate-beta-alanine ligase Racemase_4 PF13615.1 KKK27209.1 - 0.28 11.4 1.5 4.5 7.5 0.4 2.5 2 1 0 2 2 2 0 Putative alanine racemase 7TM_GPCR_Str PF10326.4 KKK27210.1 - 0.001 18.2 2.3 0.013 14.6 0.3 2.1 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Str Baculo_11_kDa PF06143.6 KKK27210.1 - 0.095 12.0 2.7 4.7 6.6 0.3 3.0 3 0 0 3 3 3 0 Baculovirus 11 kDa family Tetraspannin PF00335.15 KKK27210.1 - 0.68 9.1 4.0 0.77 8.9 0.0 2.3 2 1 0 2 2 2 0 Tetraspanin family UNC-93 PF05978.11 KKK27210.1 - 3.3 7.2 7.0 0.51 9.8 1.5 1.9 1 1 1 2 2 2 0 Ion channel regulatory protein UNC-93 AA_permease PF00324.16 KKK27211.1 - 2.2e-79 267.0 43.0 3.3e-55 187.3 15.9 2.0 1 1 1 2 2 2 2 Amino acid permease AA_permease_2 PF13520.1 KKK27211.1 - 1.1e-19 70.3 46.8 1.5e-16 59.9 17.9 2.1 1 1 1 2 2 2 2 Amino acid permease Epimerase PF01370.16 KKK27212.1 - 1.3e-09 37.8 0.0 0.00041 19.8 0.0 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 KKK27212.1 - 3.2e-06 26.2 0.0 6.6e-06 25.2 0.0 1.6 2 0 0 2 2 2 1 Male sterility protein Semialdhyde_dh PF01118.19 KKK27212.1 - 5.1e-05 23.5 0.0 0.00011 22.5 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NmrA PF05368.8 KKK27212.1 - 0.00011 21.5 0.1 0.00021 20.6 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.12 KKK27212.1 - 0.00092 18.1 0.0 0.4 9.5 0.0 2.1 2 0 0 2 2 2 2 RmlD substrate binding domain Saccharop_dh PF03435.13 KKK27212.1 - 0.0034 16.4 0.0 0.0048 15.9 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_10 PF13460.1 KKK27212.1 - 0.0048 16.9 0.1 0.01 15.8 0.1 1.8 1 1 0 1 1 1 1 NADH(P)-binding DXP_reductoisom PF02670.11 KKK27212.1 - 0.011 16.2 0.0 0.02 15.4 0.0 1.5 1 1 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Polysacc_synt_2 PF02719.10 KKK27212.1 - 0.11 11.3 0.0 0.17 10.7 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Fungal_trans_2 PF11951.3 KKK27213.1 - 3e-07 29.3 0.0 8e-07 27.9 0.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain ORC4_C PF14629.1 KKK27213.1 - 0.032 13.5 0.1 0.059 12.7 0.1 1.3 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 4 C-terminus AA_permease_2 PF13520.1 KKK27214.1 - 1.7e-52 178.4 47.5 2.1e-52 178.0 32.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KKK27214.1 - 6e-28 97.4 40.8 8.1e-28 96.9 28.3 1.1 1 0 0 1 1 1 1 Amino acid permease Ribosomal_S19e PF01090.14 KKK27215.1 - 2.6e-57 192.1 0.3 3e-57 191.9 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e Pex2_Pex12 PF04757.9 KKK27216.1 - 4e-41 140.9 0.9 4e-41 140.9 0.7 1.5 2 0 0 2 2 2 1 Pex2 / Pex12 amino terminal region zf-C3HC4_4 PF15227.1 KKK27216.1 - 0.00078 19.2 4.9 0.0018 18.1 3.4 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 KKK27216.1 - 0.87 9.6 8.7 0.96 9.5 3.8 2.4 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Na_trans_assoc PF06512.8 KKK27216.1 - 4.2 7.2 8.5 0.47 10.4 0.2 2.7 2 1 1 3 3 3 0 Sodium ion transport-associated bZIP_1 PF00170.16 KKK27217.1 - 3.4e-08 33.3 12.1 1.8e-07 31.0 6.9 2.2 1 1 1 2 2 2 2 bZIP transcription factor bZIP_2 PF07716.10 KKK27217.1 - 4.8e-05 23.0 12.7 0.0028 17.4 4.9 2.3 1 1 1 2 2 2 2 Basic region leucine zipper DUF972 PF06156.8 KKK27217.1 - 0.00021 21.6 1.1 0.00021 21.6 0.8 1.7 1 1 1 2 2 2 1 Protein of unknown function (DUF972) Phlebovirus_NSM PF07246.6 KKK27217.1 - 0.0005 19.3 2.3 0.00066 18.9 1.6 1.1 1 0 0 1 1 1 1 Phlebovirus nonstructural protein NS-M Jnk-SapK_ap_N PF09744.4 KKK27217.1 - 0.0022 17.9 8.9 0.006 16.5 6.2 1.6 1 1 0 1 1 1 1 JNK_SAPK-associated protein-1 PTRF_SDPR PF15237.1 KKK27217.1 - 0.0061 15.9 4.5 0.0088 15.4 3.1 1.1 1 0 0 1 1 1 1 PTRF/SDPR family Phage_lysis PF03245.8 KKK27217.1 - 0.043 13.8 3.4 0.061 13.3 2.3 1.2 1 0 0 1 1 1 0 Bacteriophage Rz lysis protein TMF_DNA_bd PF12329.3 KKK27217.1 - 0.055 13.2 2.7 0.13 12.0 1.5 1.8 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Microtub_assoc PF07989.6 KKK27217.1 - 0.079 12.7 0.2 0.079 12.7 0.2 2.2 1 1 1 2 2 2 0 Microtubule associated Apelin PF15360.1 KKK27217.1 - 0.095 12.9 1.3 0.29 11.3 0.9 1.8 1 0 0 1 1 1 0 APJ endogenous ligand DUF3492 PF11997.3 KKK27217.1 - 0.17 11.4 0.8 0.2 11.1 0.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3492) OmpH PF03938.9 KKK27217.1 - 0.24 11.3 6.2 0.33 10.8 4.3 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) IncA PF04156.9 KKK27217.1 - 0.28 10.7 5.9 0.4 10.2 4.1 1.2 1 0 0 1 1 1 0 IncA protein Spectrin PF00435.16 KKK27217.1 - 0.29 11.4 7.2 0.23 11.7 3.1 2.0 1 1 1 2 2 2 0 Spectrin repeat DivIC PF04977.10 KKK27217.1 - 0.34 10.4 0.1 0.34 10.4 0.1 2.3 1 1 1 2 2 2 0 Septum formation initiator CCDC155 PF14662.1 KKK27217.1 - 0.41 10.2 10.4 1.3 8.6 7.3 1.6 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 HAUS6_N PF14661.1 KKK27217.1 - 0.64 9.3 6.9 0.84 8.9 4.8 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus DUF904 PF06005.7 KKK27217.1 - 0.65 10.3 10.3 0.084 13.1 4.0 1.8 2 1 0 2 2 1 0 Protein of unknown function (DUF904) DUF202 PF02656.10 KKK27218.1 - 2.2 8.5 4.6 4.7 7.4 1.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF202) IBN_N PF03810.14 KKK27219.1 - 9.2e-13 47.9 1.3 3.1e-12 46.2 0.1 2.6 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.7 KKK27219.1 - 0.0018 18.2 2.2 0.014 15.3 0.0 3.5 4 0 0 4 4 4 1 Exportin 1-like protein Phosphoesterase PF04185.9 KKK27220.1 - 1.9e-32 112.8 4.6 6.7e-32 111.1 3.2 1.8 1 1 0 1 1 1 1 Phosphoesterase family NAD_Gly3P_dh_N PF01210.18 KKK27222.1 - 0.11 12.1 0.1 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ILVD_EDD PF00920.16 KKK27223.1 - 2.5e-203 676.2 1.3 2.9e-203 676.0 0.9 1.0 1 0 0 1 1 1 1 Dehydratase family Ldh_2 PF02615.9 KKK27224.1 - 6.2e-101 337.4 0.0 7.5e-101 337.2 0.0 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase Abhydrolase_6 PF12697.2 KKK27225.1 - 1.1e-22 81.0 0.9 6.3e-22 78.5 0.4 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KKK27225.1 - 1.8e-12 47.2 0.0 9.4e-12 44.9 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family DSPc PF00782.15 KKK27225.1 - 1.2e-10 41.1 0.0 3.9e-10 39.4 0.0 1.8 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Abhydrolase_1 PF00561.15 KKK27225.1 - 1e-09 38.2 0.0 7.6e-09 35.4 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold PTPlike_phytase PF14566.1 KKK27225.1 - 0.00047 20.2 0.0 0.00078 19.5 0.0 1.4 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.22 KKK27225.1 - 0.00048 19.5 0.0 0.0011 18.2 0.0 1.6 2 0 0 2 2 2 1 Protein-tyrosine phosphatase Ser_hydrolase PF06821.8 KKK27225.1 - 0.0011 18.5 0.0 0.0041 16.7 0.0 1.8 2 0 0 2 2 2 1 Serine hydrolase Thioesterase PF00975.15 KKK27225.1 - 0.0099 16.1 0.1 0.017 15.3 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Hydrolase_4 PF12146.3 KKK27225.1 - 0.02 14.7 0.0 0.058 13.2 0.0 1.8 1 0 0 1 1 1 0 Putative lysophospholipase FSH1 PF03959.8 KKK27225.1 - 0.027 13.9 0.0 2.9 7.2 0.0 2.2 2 0 0 2 2 2 0 Serine hydrolase (FSH1) DUF2305 PF10230.4 KKK27225.1 - 0.072 12.4 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) LCAT PF02450.10 KKK27225.1 - 0.16 10.8 0.0 0.28 10.1 0.0 1.3 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase PGAP1 PF07819.8 KKK27225.1 - 0.17 11.4 0.0 0.67 9.4 0.0 1.9 1 1 0 1 1 1 0 PGAP1-like protein GPI-anchored PF10342.4 KKK27226.1 - 8.5e-23 80.6 0.3 8.5e-23 80.6 0.2 3.5 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family TFIIA PF03153.8 KKK27226.1 - 0.66 9.8 16.7 0.81 9.5 11.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Aldedh PF00171.17 KKK27227.1 - 1.4e-132 442.2 1.4 1.7e-132 442.0 0.9 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Protoglobin PF11563.3 KKK27228.1 - 1.9e-42 144.6 1.6 9.5e-36 122.8 0.3 2.1 1 1 1 2 2 2 2 Protoglobin Cellulase PF00150.13 KKK27229.1 - 2.2e-18 66.4 0.7 3e-18 66.0 0.0 1.5 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_42 PF02449.10 KKK27229.1 - 0.062 12.4 0.0 0.27 10.3 0.0 1.8 2 0 0 2 2 2 0 Beta-galactosidase Glyco_hydro_35 PF01301.14 KKK27229.1 - 0.11 11.7 0.0 0.22 10.8 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolases family 35 PH_6 PF15406.1 KKK27230.1 - 5.1e-38 129.5 1.2 5.1e-38 129.5 0.8 2.9 2 1 1 3 3 3 1 Pleckstrin homology domain PH PF00169.24 KKK27230.1 - 0.0001 22.4 0.0 0.00023 21.3 0.0 1.6 1 0 0 1 1 1 1 PH domain Sulfate_transp PF00916.15 KKK27231.1 - 1.9e-25 89.4 2.6 1.9e-25 89.4 1.8 1.5 2 0 0 2 2 2 1 Sulfate transporter family cNMP_binding PF00027.24 KKK27231.1 - 2e-16 59.5 0.0 3.5e-16 58.7 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.16 KKK27231.1 - 1.4e-09 37.3 0.1 2.7e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 STAS domain Ceramidase PF05875.7 KKK27231.1 - 0.47 9.5 3.8 4.2 6.4 0.8 2.2 2 0 0 2 2 2 0 Ceramidase Sulfate_transp PF00916.15 KKK27232.1 - 1.4e-09 37.3 5.4 2.6e-09 36.5 3.8 1.4 1 0 0 1 1 1 1 Sulfate transporter family DUF4209 PF13910.1 KKK27232.1 - 0.13 12.3 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4209) Sld5 PF05916.6 KKK27233.1 - 8.6e-14 51.7 0.0 1.3e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 GINS complex protein DUF3016 PF11454.3 KKK27233.1 - 0.14 11.7 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3016) HMG_box PF00505.14 KKK27234.1 - 1.3e-12 47.7 1.6 2.9e-12 46.6 1.1 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box MAT_Alpha1 PF04769.7 KKK27234.1 - 0.0096 15.2 0.1 0.019 14.3 0.1 1.4 1 0 0 1 1 1 1 Mating-type protein MAT alpha 1 HMG_box_2 PF09011.5 KKK27234.1 - 0.031 14.6 1.1 0.073 13.4 0.8 1.7 1 0 0 1 1 1 0 HMG-box domain HSP70 PF00012.15 KKK27235.1 - 1.2e-10 40.0 0.4 2.7e-09 35.5 0.1 2.0 2 0 0 2 2 2 2 Hsp70 protein zf-SAP30 PF13866.1 KKK27235.1 - 0.018 14.7 0.1 0.039 13.6 0.1 1.5 1 0 0 1 1 1 0 SAP30 zinc-finger MreB_Mbl PF06723.8 KKK27235.1 - 0.092 11.3 0.0 0.32 9.5 0.0 1.7 2 0 0 2 2 2 0 MreB/Mbl protein DUF3445 PF11927.3 KKK27236.1 - 1.6e-81 273.4 0.1 2e-81 273.0 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) DUF1537 PF07005.6 KKK27237.1 - 5.8e-16 58.8 5.0 7.9e-15 55.1 3.4 2.2 1 1 0 1 1 1 1 Protein of unknown function, DUF1537 CDC45 PF02724.9 KKK27238.1 - 3.9e-249 827.9 0.8 1.7e-248 825.7 0.5 2.5 1 1 0 1 1 1 1 CDC45-like protein AIF-MLS PF14962.1 KKK27238.1 - 0.0066 16.1 7.1 0.012 15.2 5.0 1.4 1 0 0 1 1 1 1 Mitochondria Localisation Sequence Nop14 PF04147.7 KKK27238.1 - 0.096 10.5 27.9 0.33 8.8 7.6 2.1 2 0 0 2 2 2 0 Nop14-like family SDA1 PF05285.7 KKK27238.1 - 0.35 10.0 29.3 0.59 9.3 5.9 2.2 2 0 0 2 2 2 0 SDA1 MIP-T3 PF10243.4 KKK27238.1 - 0.83 8.0 34.8 0.093 11.1 4.5 2.1 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 BUD22 PF09073.5 KKK27238.1 - 2.9 6.8 42.8 0.2 10.6 12.8 2.2 2 0 0 2 2 2 0 BUD22 Daxx PF03344.10 KKK27238.1 - 5.5 5.3 32.1 0.98 7.8 5.2 2.1 2 0 0 2 2 2 0 Daxx Family Peptidase_C13 PF01650.13 KKK27239.1 - 7e-41 140.2 0.1 9.9e-41 139.7 0.1 1.1 1 0 0 1 1 1 1 Peptidase C13 family Mito_carr PF00153.22 KKK27240.1 - 3.4e-44 148.4 9.5 1.8e-16 59.6 0.3 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Flavin_Reduct PF01613.13 KKK27241.1 - 5.4e-18 65.3 0.0 7.7e-18 64.8 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain DUF447 PF04289.7 KKK27241.1 - 0.11 12.0 0.0 0.19 11.2 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF447) Abhydrolase_1 PF00561.15 KKK27242.1 - 3.8e-10 39.6 0.0 2.3e-09 37.1 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KKK27242.1 - 4.5e-08 33.2 0.0 9e-08 32.2 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family PAP_central PF04928.12 KKK27243.1 - 1.6e-104 348.2 0.0 2.1e-104 347.8 0.0 1.1 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.10 KKK27243.1 - 6.1e-50 168.8 0.0 1e-49 168.0 0.0 1.3 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.18 KKK27243.1 - 8e-10 38.9 0.0 2.6e-09 37.2 0.0 1.8 2 0 0 2 2 2 1 Nucleotidyltransferase domain 4HBT_3 PF13622.1 KKK27245.1 - 9.4e-43 146.7 0.2 1.5e-42 146.1 0.2 1.3 1 1 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.10 KKK27245.1 - 5.1e-24 84.3 0.0 2.9e-12 46.3 0.0 4.1 3 1 0 3 3 3 3 Acyl-CoA thioesterase Succ_CoA_lig PF13607.1 KKK27245.1 - 0.061 12.9 0.0 0.22 11.0 0.0 1.9 2 0 0 2 2 2 0 Succinyl-CoA ligase like flavodoxin domain Sec61_beta PF03911.11 KKK27246.1 - 4.2e-19 68.0 0.7 5.4e-19 67.6 0.5 1.2 1 0 0 1 1 1 1 Sec61beta family SCIMP PF15050.1 KKK27247.1 - 0.035 14.0 3.5 0.57 10.0 0.0 3.1 3 0 0 3 3 3 0 SCIMP protein DUF3357 PF11837.3 KKK27247.1 - 0.49 10.2 2.5 0.86 9.4 0.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF3357) Vezatin PF12632.2 KKK27249.1 - 5.4e-56 189.4 0.0 1.2e-55 188.3 0.0 1.6 1 0 0 1 1 1 1 Mysoin-binding motif of peroxisomes PCNA_N PF00705.13 KKK27249.1 - 1.1e-52 176.8 2.5 2.2e-52 175.8 1.8 1.5 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.10 KKK27249.1 - 3.8e-51 172.3 0.0 7.3e-51 171.4 0.0 1.5 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.8 KKK27249.1 - 1.5e-05 24.2 0.0 2.3e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Rad9 Hus1 PF04005.7 KKK27249.1 - 0.012 14.5 0.2 0.074 11.9 0.0 2.0 2 0 0 2 2 2 0 Hus1-like protein EB1 PF03271.12 KKK27250.1 - 2.8e-17 62.4 1.1 4.9e-17 61.6 0.8 1.4 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.26 KKK27250.1 - 3.4e-06 27.0 1.4 7.6e-06 25.9 0.6 1.7 2 0 0 2 2 2 1 Calponin homology (CH) domain DUF2013 PF09431.5 KKK27251.1 - 5.2e-52 175.3 1.4 5.2e-52 175.3 1.0 1.9 2 1 0 2 2 2 1 Protein of unknown function (DUF2013) APG9 PF04109.11 KKK27252.1 - 1.4e-169 563.8 3.8 1.9e-169 563.4 2.6 1.1 1 0 0 1 1 1 1 Autophagy protein Apg9 Glyco_hydro_47 PF01532.15 KKK27253.1 - 4.1e-185 615.7 0.1 5.1e-185 615.4 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 SprT-like PF10263.4 KKK27254.1 - 4.7e-52 175.7 0.3 7.5e-52 175.1 0.2 1.3 1 0 0 1 1 1 1 SprT-like family Peptidase_MA_2 PF13485.1 KKK27254.1 - 0.011 15.7 0.1 0.043 13.8 0.0 2.0 2 0 0 2 2 2 0 Peptidase MA superfamily Peptidase_M30 PF10460.4 KKK27254.1 - 0.072 11.9 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Peptidase M30 Aminotran_1_2 PF00155.16 KKK27255.1 - 3.6e-39 134.7 0.0 4.5e-39 134.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Glyco_hydro_17 PF00332.13 KKK27256.1 - 1.4e-07 30.9 0.7 2.4e-06 26.8 0.1 2.2 2 0 0 2 2 2 2 Glycosyl hydrolases family 17 Peripla_BP_4 PF13407.1 KKK27256.1 - 0.042 13.2 0.4 2.5 7.3 0.0 2.5 1 1 2 3 3 3 0 Periplasmic binding protein domain Glyco_hydro_72 PF03198.9 KKK27257.1 - 1.2e-110 369.3 9.9 1.9e-107 358.9 6.9 2.1 1 1 0 1 1 1 1 Glucanosyltransferase X8 PF07983.8 KKK27257.1 - 1e-21 77.1 5.6 3.4e-21 75.5 3.9 2.0 1 0 0 1 1 1 1 X8 domain DUF2804 PF10974.3 KKK27257.1 - 0.17 10.6 0.6 0.32 9.8 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2804) Glucan_synthase PF02364.10 KKK27258.1 - 0 1503.1 0.0 0 1502.7 0.0 1.1 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.1 KKK27258.1 - 5.1e-24 84.4 0.2 1.4e-23 83.0 0.2 1.7 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 HSF_DNA-bind PF00447.12 KKK27259.1 - 1.9e-38 130.8 0.4 3.6e-38 129.9 0.3 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding Response_reg PF00072.19 KKK27259.1 - 3.4e-17 62.4 0.0 7.1e-17 61.4 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain CENP-Q PF13094.1 KKK27259.1 - 0.007 16.4 6.3 0.017 15.1 4.4 1.6 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit SlyX PF04102.7 KKK27259.1 - 0.3 11.4 8.7 0.16 12.3 3.8 2.4 2 0 0 2 2 2 0 SlyX Redoxin PF08534.5 KKK27260.1 - 1.3e-26 92.9 0.0 1.7e-26 92.4 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 KKK27260.1 - 5.5e-08 32.5 0.0 7.1e-08 32.1 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family NIF3 PF01784.13 KKK27261.1 - 2.9e-59 200.5 0.0 3.6e-59 200.2 0.0 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) BolA PF01722.13 KKK27262.1 - 1.7e-22 79.1 0.0 2.9e-22 78.3 0.0 1.4 1 0 0 1 1 1 1 BolA-like protein Dak2 PF02734.12 KKK27262.1 - 0.046 13.3 0.1 0.055 13.1 0.1 1.1 1 0 0 1 1 1 0 DAK2 domain W2 PF02020.13 KKK27263.1 - 1.2e-16 60.3 11.2 1.2e-16 60.3 7.7 2.6 2 1 1 3 3 3 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.19 KKK27263.1 - 1.3e-10 40.2 13.2 1.5e-05 24.2 0.4 3.7 1 1 1 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 KKK27263.1 - 1.1e-06 28.0 13.0 0.0044 16.5 0.2 4.1 1 1 3 4 4 4 4 Hexapeptide repeat of succinyl-transferase NTP_transferase PF00483.18 KKK27263.1 - 8.6e-06 25.2 0.0 1.7e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.2 KKK27263.1 - 0.0047 17.0 0.0 0.011 15.8 0.0 1.6 1 0 0 1 1 1 1 MobA-like NTP transferase domain Keratin_assoc PF09775.4 KKK27263.1 - 0.13 11.7 0.0 0.31 10.5 0.0 1.6 1 0 0 1 1 1 0 Keratinocyte-associated protein 2 MARVEL PF01284.18 KKK27265.1 - 0.00015 21.5 6.7 0.00027 20.8 4.6 1.4 1 1 0 1 1 1 1 Membrane-associating domain PTS_EIIC PF02378.13 KKK27265.1 - 0.01 14.6 0.7 0.014 14.2 0.5 1.2 1 0 0 1 1 1 0 Phosphotransferase system, EIIC DUF1769 PF08588.5 KKK27265.1 - 0.13 12.2 0.0 0.39 10.6 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1769) RasGAP PF00616.14 KKK27266.1 - 1.3e-46 158.7 0.0 2.4e-46 157.8 0.0 1.5 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase C2 PF00168.25 KKK27266.1 - 2.5e-06 27.2 0.2 1.1e-05 25.1 0.0 2.1 2 0 0 2 2 2 1 C2 domain Mog1 PF04603.7 KKK27267.1 - 2.3e-18 66.4 0.1 4.3e-12 46.1 0.0 3.0 1 1 1 2 2 2 2 Ran-interacting Mog1 protein HSP9_HSP12 PF04119.7 KKK27268.1 - 2.6e-29 101.0 9.4 1.5e-28 98.6 6.2 2.0 2 0 0 2 2 2 1 Heat shock protein 9/12 YtxH PF12732.2 KKK27268.1 - 0.17 12.2 2.2 0.26 11.6 1.5 1.5 1 1 0 1 1 1 0 YtxH-like protein DUF3484 PF11983.3 KKK27268.1 - 0.26 12.1 1.7 5.1 8.0 1.1 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF3484) Tombus_movement PF05318.7 KKK27268.1 - 0.36 11.4 2.1 0.45 11.1 1.3 1.3 1 1 0 1 1 1 0 Tombusvirus movement protein NYN PF01936.13 KKK27269.1 - 4.5e-05 23.7 0.0 0.00024 21.3 0.0 2.2 2 1 0 2 2 2 1 NYN domain COG6 PF06419.6 KKK27270.1 - 1.8e-243 809.2 0.3 2.1e-243 809.0 0.2 1.0 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 Tnp_DNA_bind PF14706.1 KKK27270.1 - 0.051 13.2 0.1 0.17 11.6 0.0 1.9 1 0 0 1 1 1 0 Transposase DNA-binding Laminin_II PF06009.7 KKK27271.1 - 0.023 14.4 5.5 1 9.1 1.2 2.4 2 0 0 2 2 2 0 Laminin Domain II Reo_sigmaC PF04582.7 KKK27271.1 - 0.075 12.1 1.3 0.42 9.7 1.1 1.8 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Jnk-SapK_ap_N PF09744.4 KKK27271.1 - 0.42 10.5 15.2 1.7 8.6 6.2 2.1 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 Phage_GP20 PF06810.6 KKK27271.1 - 1.2 8.5 8.0 0.37 10.2 0.2 2.9 2 1 1 3 3 3 0 Phage minor structural protein GP20 DUF948 PF06103.6 KKK27271.1 - 1.2 9.0 4.5 27 4.7 0.3 3.1 2 1 2 4 4 4 0 Bacterial protein of unknown function (DUF948) Syntaxin-6_N PF09177.6 KKK27271.1 - 2.5 8.5 9.6 4.9 7.6 0.4 3.6 1 1 3 4 4 4 0 Syntaxin 6, N-terminal Adeno_PIX PF03955.9 KKK27271.1 - 7.9 7.0 7.6 6.6 7.3 0.1 3.2 2 1 0 2 2 2 0 Adenovirus hexon-associated protein (IX) Proteasome PF00227.21 KKK27273.1 - 6.5e-47 159.2 0.0 8e-47 158.9 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.3 KKK27273.1 - 1.5e-14 52.9 2.6 3.3e-14 51.8 1.8 1.6 1 0 0 1 1 1 1 Proteasome beta subunits C terminal Daxx PF03344.10 KKK27274.1 - 0.0042 15.6 13.6 0.0081 14.7 9.4 1.4 1 0 0 1 1 1 1 Daxx Family Baculo_PEP_C PF04513.7 KKK27274.1 - 0.43 10.3 1.8 1.1 9.0 1.2 1.7 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Nop14 PF04147.7 KKK27274.1 - 0.46 8.3 15.0 0.84 7.4 10.4 1.3 1 0 0 1 1 1 0 Nop14-like family Pox_Ag35 PF03286.9 KKK27274.1 - 1.7 8.1 8.9 4 6.9 6.2 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein RNA_pol_3_Rpc31 PF11705.3 KKK27274.1 - 6 6.7 18.9 14 5.5 13.1 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 KH_1 PF00013.24 KKK27276.1 - 3.9e-42 141.7 3.6 3.1e-16 58.7 0.2 3.2 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 KKK27276.1 - 4.8e-30 102.6 11.0 5e-11 41.9 1.4 3.4 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 KKK27276.1 - 2.4e-11 43.0 3.7 0.014 14.9 0.2 3.2 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 KKK27276.1 - 0.00024 20.6 1.2 1.1 8.9 0.0 3.2 3 0 0 3 3 3 2 KH domain KH_5 PF13184.1 KKK27276.1 - 0.049 13.4 7.6 0.98 9.2 0.1 3.2 3 0 0 3 3 3 0 NusA-like KH domain CENP-K PF11802.3 KKK27277.1 - 0.012 14.8 7.9 0.028 13.6 0.0 2.9 2 1 1 3 3 3 0 Centromere-associated protein K DUF4201 PF13870.1 KKK27277.1 - 0.63 9.4 16.2 0.21 11.0 0.5 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4201) Fib_alpha PF08702.5 KKK27277.1 - 0.85 9.7 17.8 0.31 11.1 2.3 2.7 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family CCDC84 PF14968.1 KKK27277.1 - 1.1 8.7 4.2 0.39 10.1 0.1 2.0 2 1 0 2 2 2 0 Coiled coil protein 84 COX16 PF14138.1 KKK27277.1 - 7.1 6.8 8.3 30 4.8 0.3 2.9 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein COX16 Helicase_C PF00271.26 KKK27278.1 - 1.2e-21 76.3 0.1 4.5e-18 64.8 0.0 2.7 2 0 0 2 2 2 2 Helicase conserved C-terminal domain DEAD PF00270.24 KKK27278.1 - 6.9e-21 74.4 0.0 2.2e-20 72.8 0.0 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase HRDC PF00570.18 KKK27278.1 - 6.3e-09 35.4 0.0 1.9e-08 33.8 0.0 1.9 1 0 0 1 1 1 1 HRDC domain RQC PF09382.5 KKK27278.1 - 7.1e-05 22.4 0.0 0.00045 19.9 0.0 2.3 1 1 0 1 1 1 1 RQC domain Kelch_3 PF13415.1 KKK27279.1 - 4.8e-31 106.1 10.1 1.6e-08 34.5 0.1 6.9 6 0 0 6 6 6 4 Galactose oxidase, central domain DUF4110 PF13422.1 KKK27279.1 - 6.2e-30 102.9 1.8 6.2e-30 102.9 1.3 3.1 3 0 0 3 3 3 1 Domain of unknown function (DUF4110) Kelch_4 PF13418.1 KKK27279.1 - 2.3e-23 81.6 18.6 1.6e-06 27.8 0.0 6.9 6 1 0 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.1 KKK27279.1 - 8.3e-16 57.5 4.4 0.00017 21.4 0.0 6.3 6 0 0 6 6 6 4 Kelch motif Kelch_6 PF13964.1 KKK27279.1 - 5.1e-14 51.7 7.8 0.0023 18.0 0.1 5.8 6 0 0 6 6 6 3 Kelch motif Kelch_2 PF07646.10 KKK27279.1 - 1.3e-11 43.7 11.0 0.005 16.5 0.0 5.9 6 1 0 6 6 6 3 Kelch motif Kelch_1 PF01344.20 KKK27279.1 - 3e-08 33.0 0.7 0.27 10.8 0.0 5.5 5 0 0 5 5 5 3 Kelch motif Pyridoxal_deC PF00282.14 KKK27280.1 - 1e-29 103.1 0.0 1.5e-29 102.6 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.16 KKK27280.1 - 1.8e-05 24.0 0.0 2.3e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase SLA_LP_auto_ag PF05889.8 KKK27280.1 - 0.0089 14.5 0.0 0.014 13.8 0.0 1.2 1 0 0 1 1 1 1 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) BRK PF07533.11 KKK27280.1 - 0.07 12.6 0.0 0.24 10.9 0.0 1.9 2 0 0 2 2 2 0 BRK domain Aminotran_5 PF00266.14 KKK27280.1 - 0.13 10.9 0.0 0.32 9.6 0.0 1.7 1 1 0 1 1 1 0 Aminotransferase class-V Abhydrolase_6 PF12697.2 KKK27281.1 - 3.3e-11 43.5 0.0 1.7e-10 41.1 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KKK27281.1 - 6.8e-09 35.6 0.0 1.3e-08 34.6 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KKK27281.1 - 7.5e-08 32.2 0.0 1.9e-07 30.9 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KKK27281.1 - 0.026 14.3 0.0 0.068 13.0 0.0 1.7 1 0 0 1 1 1 0 Putative lysophospholipase Peptidase_S9 PF00326.16 KKK27281.1 - 0.054 12.7 0.1 0.61 9.2 0.0 2.5 2 1 0 2 2 2 0 Prolyl oligopeptidase family Esterase PF00756.15 KKK27281.1 - 0.064 12.6 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Mon1 PF03164.9 KKK27282.1 - 1.6e-120 402.5 0.1 1.8e-120 402.3 0.0 1.0 1 0 0 1 1 1 1 Trafficking protein Mon1 zf-HIT PF04438.11 KKK27283.1 - 2.2e-09 36.7 12.0 3.6e-09 36.1 8.3 1.4 1 0 0 1 1 1 1 HIT zinc finger KRE9 PF05390.6 KKK27283.1 - 0.066 13.5 0.6 0.54 10.6 0.0 2.2 2 0 0 2 2 2 0 Yeast cell wall synthesis protein KRE9/KNH1 HNOBA PF07701.9 KKK27283.1 - 0.26 10.4 3.4 0.38 9.9 2.3 1.2 1 0 0 1 1 1 0 Heme NO binding associated Ribosomal_60s PF00428.14 KKK27283.1 - 2.1 8.7 16.0 3.2 8.2 6.2 2.5 1 1 1 2 2 2 0 60s Acidic ribosomal protein Dopey_N PF04118.9 KKK27284.1 - 4.9e-96 321.1 0.0 1.2e-93 313.2 0.0 3.1 1 1 0 1 1 1 1 Dopey, N-terminal MazG PF03819.12 KKK27284.1 - 0.14 12.1 0.0 0.34 10.8 0.0 1.6 1 0 0 1 1 1 0 MazG nucleotide pyrophosphohydrolase domain CAP_N PF01213.14 KKK27284.1 - 1.6 7.9 3.2 3.2 6.9 2.2 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Acetyltransf_1 PF00583.19 KKK27285.1 - 0.0058 16.6 0.0 0.0083 16.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.1 KKK27285.1 - 0.0074 16.4 0.0 0.011 15.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 KKK27285.1 - 0.012 15.5 0.0 0.017 15.0 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 KKK27285.1 - 0.15 11.8 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein KAR9 PF08580.5 KKK27286.1 - 1.9e-164 548.6 5.8 1.9e-164 548.6 4.1 2.2 3 0 0 3 3 3 1 Yeast cortical protein KAR9 MAD PF05557.8 KKK27286.1 - 0.093 10.8 2.5 0.5 8.3 1.8 1.8 1 1 1 2 2 2 0 Mitotic checkpoint protein Prefoldin PF02996.12 KKK27286.1 - 1.8 8.2 4.3 29 4.3 0.1 3.8 3 1 1 4 4 4 0 Prefoldin subunit Prefoldin_2 PF01920.15 KKK27286.1 - 2.6 7.8 6.8 1.3 8.8 0.1 3.5 4 0 0 4 4 4 0 Prefoldin subunit Methyltransf_26 PF13659.1 KKK27287.1 - 3.2e-15 56.1 0.0 5.2e-15 55.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KKK27287.1 - 7.7e-05 22.1 0.8 0.09 12.1 0.1 2.2 1 1 0 2 2 2 2 Methyltransferase small domain Methyltransf_12 PF08242.7 KKK27287.1 - 0.00094 19.6 6.6 0.0016 18.8 3.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 KKK27287.1 - 0.071 12.8 0.0 0.2 11.3 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Menin PF05053.8 KKK27287.1 - 0.12 10.5 0.7 0.14 10.2 0.5 1.2 1 0 0 1 1 1 0 Menin Methyltransf_4 PF02390.12 KKK27287.1 - 0.12 11.3 0.4 0.33 9.9 0.0 1.7 1 1 1 2 2 2 0 Putative methyltransferase Methyltransf_25 PF13649.1 KKK27287.1 - 0.15 12.4 0.0 0.26 11.6 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain Complex1_LYR PF05347.10 KKK27288.1 - 5.9e-08 32.3 0.0 9.4e-08 31.7 0.0 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KKK27288.1 - 2.3e-06 27.6 0.0 4e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 KKK27288.1 - 1.7e-05 25.1 0.0 2.4e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Acylphosphatase PF00708.13 KKK27289.1 - 5.3e-21 74.5 0.1 6.4e-21 74.2 0.1 1.1 1 0 0 1 1 1 1 Acylphosphatase MBOAT PF03062.14 KKK27290.1 - 2.6e-41 141.8 12.9 7.1e-41 140.3 8.9 1.7 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family PufQ PF05398.6 KKK27290.1 - 0.0016 18.4 1.1 0.75 9.8 0.0 2.8 2 0 0 2 2 2 2 PufQ cytochrome subunit PriCT_1 PF08708.6 KKK27291.1 - 0.15 11.8 1.0 3.4 7.5 0.1 2.9 3 0 0 3 3 3 0 Primase C terminal 1 (PriCT-1) AOX PF01786.12 KKK27292.1 - 3e-92 307.6 0.0 3.8e-92 307.3 0.0 1.1 1 0 0 1 1 1 1 Alternative oxidase HEAT_2 PF13646.1 KKK27294.1 - 0.036 14.3 0.0 4.3 7.6 0.0 2.6 1 1 1 2 2 2 0 HEAT repeats Methyltransf_23 PF13489.1 KKK27296.1 - 7.6e-20 71.2 0.0 1.1e-19 70.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KKK27296.1 - 2.4e-08 33.7 0.0 8e-08 32.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KKK27296.1 - 7.5e-08 32.7 0.0 3e-07 30.8 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KKK27296.1 - 2.6e-07 31.0 0.0 5.3e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KKK27296.1 - 4e-07 30.6 0.0 8.7e-06 26.2 0.0 2.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KKK27296.1 - 1.9e-05 24.9 0.0 5.5e-05 23.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KKK27296.1 - 0.0034 17.3 0.0 0.0072 16.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 KKK27296.1 - 0.028 13.8 0.0 0.042 13.3 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_4 PF02390.12 KKK27296.1 - 0.051 12.6 0.0 0.085 11.8 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Ubie_methyltran PF01209.13 KKK27296.1 - 0.067 12.2 0.0 0.21 10.6 0.0 1.9 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family PrmA PF06325.8 KKK27296.1 - 0.17 11.0 0.0 0.25 10.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DUF77 PF01910.12 KKK27297.1 - 1.2e-27 95.3 0.1 1.4e-27 95.1 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function DUF77 LSM PF01423.17 KKK27298.1 - 0.0011 18.5 0.0 0.0014 18.0 0.0 1.2 1 0 0 1 1 1 1 LSM domain Gar1 PF04410.9 KKK27298.1 - 0.13 11.6 0.1 0.17 11.3 0.1 1.1 1 0 0 1 1 1 0 Gar1/Naf1 RNA binding region DUF2763 PF10961.3 KKK27298.1 - 0.32 11.4 12.0 0.46 10.9 8.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2763) DUF1688 PF07958.6 KKK27299.1 - 1.4e-177 590.5 0.0 1.5e-177 590.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) Gtr1_RagA PF04670.7 KKK27300.1 - 1.2e-92 309.2 0.2 1.5e-92 308.9 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.16 KKK27300.1 - 4.4e-08 32.5 0.0 6.3e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 KKK27300.1 - 5.4e-08 32.3 0.0 8.4e-08 31.7 0.0 1.3 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KKK27300.1 - 6.4e-06 26.6 0.0 1.4e-05 25.5 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 KKK27300.1 - 8.8e-06 25.6 0.0 3.7e-05 23.6 0.0 1.9 1 1 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KKK27300.1 - 0.00064 19.1 0.0 0.0011 18.4 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_29 PF13555.1 KKK27300.1 - 0.0013 18.1 0.3 0.0051 16.3 0.1 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF815 PF05673.8 KKK27300.1 - 0.0092 14.9 0.1 0.02 13.8 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) ABC_tran PF00005.22 KKK27300.1 - 0.013 15.7 0.0 0.03 14.6 0.0 1.5 1 0 0 1 1 1 0 ABC transporter DUF258 PF03193.11 KKK27300.1 - 0.069 12.3 0.0 0.16 11.1 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AIG1 PF04548.11 KKK27300.1 - 0.11 11.5 0.2 0.39 9.7 0.0 2.0 2 0 0 2 2 2 0 AIG1 family AAA_10 PF12846.2 KKK27300.1 - 0.15 11.4 0.3 0.3 10.4 0.2 1.6 1 1 0 1 1 1 0 AAA-like domain G-alpha PF00503.15 KKK27300.1 - 0.19 10.3 2.6 3.3 6.3 0.7 2.2 1 1 1 2 2 2 0 G-protein alpha subunit RabGAP-TBC PF00566.13 KKK27301.1 - 4e-18 65.6 0.0 7.2e-18 64.8 0.0 1.5 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF3548 PF12068.3 KKK27301.1 - 2.5e-13 49.8 0.0 2e-08 33.8 0.0 3.5 2 1 0 2 2 2 2 Domain of unknown function (DUF3548) Rieske PF00355.21 KKK27302.1 - 1.4e-15 56.5 0.1 2.8e-15 55.6 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Ring_hydroxyl_A PF00848.14 KKK27302.1 - 6.3e-08 32.5 0.0 0.00018 21.2 0.0 2.5 1 1 1 2 2 2 2 Ring hydroxylating alpha subunit (catalytic domain) Ring_hydroxyl_A PF00848.14 KKK27303.1 - 3.5e-27 95.4 3.6 3.5e-26 92.1 2.5 2.0 1 1 0 1 1 1 1 Ring hydroxylating alpha subunit (catalytic domain) Tctex-1 PF03645.8 KKK27304.1 - 8.2e-34 115.5 0.0 9.5e-34 115.2 0.0 1.0 1 0 0 1 1 1 1 Tctex-1 family DUF202 PF02656.10 KKK27305.1 - 5.7e-12 45.6 4.9 5.7e-12 45.6 3.4 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF2207 PF09972.4 KKK27305.1 - 0.032 12.8 0.1 0.038 12.5 0.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF1673 PF07895.6 KKK27305.1 - 0.092 12.2 0.2 0.1 12.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1673) DUF2615 PF11027.3 KKK27305.1 - 0.2 11.6 0.7 0.34 10.8 0.1 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2615) DUF4234 PF14018.1 KKK27305.1 - 0.21 11.3 1.1 0.22 11.2 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4234) DUF4131 PF13567.1 KKK27305.1 - 4.4 6.6 6.7 2.3 7.6 2.6 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) WD40 PF00400.27 KKK27307.1 - 3e-44 147.3 14.7 7.4e-12 44.6 0.1 6.6 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 KKK27307.1 - 2.4e-08 32.6 2.5 0.12 10.5 0.0 3.9 3 1 0 3 3 3 3 Nucleoporin Nup120/160 DUF3312 PF11768.3 KKK27307.1 - 0.04 12.1 0.0 0.088 11.0 0.0 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3312) Hira PF07569.6 KKK27307.1 - 0.055 12.6 0.4 2.9 7.0 0.0 3.1 2 1 2 4 4 4 0 TUP1-like enhancer of split TFIIA PF03153.8 KKK27309.1 - 0.41 10.5 10.2 0.067 13.0 2.0 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit SUR7 PF06687.7 KKK27310.1 - 3.2e-51 173.9 12.9 3.8e-51 173.6 9.0 1.1 1 0 0 1 1 1 1 SUR7/PalI family Arteri_Gl PF00951.13 KKK27310.1 - 0.019 14.5 0.9 0.019 14.5 0.6 2.3 3 0 0 3 3 3 0 Arterivirus GL envelope glycoprotein Atg14 PF10186.4 KKK27312.1 - 2e-25 89.3 0.1 3e-25 88.7 0.1 1.1 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 APG6 PF04111.7 KKK27312.1 - 5.8e-06 25.5 0.0 1.1e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Autophagy protein Apg6 BRE1 PF08647.6 KKK27312.1 - 0.096 12.6 4.6 0.18 11.8 3.2 1.4 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase Exonuc_VII_L PF02601.10 KKK27312.1 - 0.22 10.6 3.1 0.34 10.0 2.2 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit IPK PF03770.11 KKK27313.1 - 7.6e-61 205.1 0.0 1.3e-60 204.4 0.0 1.4 1 0 0 1 1 1 1 Inositol polyphosphate kinase Pam17 PF08566.5 KKK27313.1 - 0.038 13.6 0.1 0.083 12.5 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial import protein Pam17 Peptidase_C13 PF01650.13 KKK27314.1 - 0.0028 17.0 0.0 0.0051 16.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase C13 family UBA PF00627.26 KKK27314.1 - 0.0041 16.9 0.2 0.071 12.9 0.1 2.8 3 0 0 3 3 3 1 UBA/TS-N domain ABC_membrane_3 PF13748.1 KKK27314.1 - 0.058 12.4 0.0 0.095 11.7 0.0 1.2 1 0 0 1 1 1 0 ABC transporter transmembrane region PLAC8 PF04749.12 KKK27315.1 - 4.6e-22 78.5 17.4 6.1e-22 78.1 12.1 1.2 1 0 0 1 1 1 1 PLAC8 family PAT1 PF09770.4 KKK27315.1 - 4.7 5.3 8.1 5.5 5.0 5.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Glycos_transf_1 PF00534.15 KKK27316.1 - 8.5e-31 106.6 0.5 3.7e-29 101.3 0.4 2.4 1 1 0 1 1 1 1 Glycosyl transferases group 1 ERCC4 PF02732.10 KKK27316.1 - 6e-27 94.1 0.1 2e-26 92.4 0.0 1.9 2 0 0 2 2 2 1 ERCC4 domain Glyco_transf_4 PF13439.1 KKK27316.1 - 2.1e-10 40.6 0.0 0.00015 21.5 0.0 2.6 2 0 0 2 2 2 2 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.1 KKK27316.1 - 4.6e-08 33.2 0.0 3.5e-06 27.2 0.0 2.6 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 KKK27316.1 - 1.7e-07 31.5 0.9 0.0056 16.8 0.2 2.9 3 0 0 3 3 3 2 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.1 KKK27316.1 - 0.00023 21.3 0.0 0.00081 19.6 0.0 1.9 1 0 0 1 1 1 1 Glycosyl transferases group 1 SAPS PF04499.10 KKK27316.1 - 0.066 11.8 1.3 0.11 11.0 0.9 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Zn_clus PF00172.13 KKK27317.1 - 3.9e-08 33.0 8.7 3.9e-08 33.0 6.0 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mhr1 PF12829.2 KKK27318.1 - 3.7e-32 109.9 0.3 8.8e-32 108.7 0.2 1.7 1 0 0 1 1 1 1 Transcriptional regulation of mitochondrial recombination DDHD PF02862.12 KKK27318.1 - 0.086 12.6 0.7 0.13 12.0 0.5 1.3 1 0 0 1 1 1 0 DDHD domain PTCB-BRCT PF12738.2 KKK27319.1 - 5.6e-43 144.6 3.4 8.2e-22 76.8 0.3 5.1 5 0 0 5 5 5 3 twin BRCT domain BRCT PF00533.21 KKK27319.1 - 1.2e-27 95.8 5.2 1.2e-13 50.9 0.2 4.3 5 0 0 5 5 5 3 BRCA1 C Terminus (BRCT) domain Snf7 PF03357.16 KKK27320.1 - 4.2e-35 120.6 15.9 8e-35 119.7 10.8 1.5 2 0 0 2 2 2 1 Snf7 V_ATPase_I PF01496.14 KKK27320.1 - 0.0097 13.8 2.4 0.011 13.5 1.7 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Ist1 PF03398.9 KKK27320.1 - 0.06 12.7 4.9 0.088 12.2 3.4 1.3 1 0 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway Dynamin_N PF00350.18 KKK27321.1 - 2.9e-16 59.7 0.0 5.9e-16 58.7 0.0 1.6 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 KKK27321.1 - 8.8e-10 38.5 0.0 4.2e-09 36.3 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KKK27321.1 - 3.5e-06 26.5 0.6 4.7e-05 22.9 0.4 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Miro PF08477.8 KKK27321.1 - 0.015 15.7 0.4 0.72 10.3 0.1 3.3 3 1 0 3 3 3 0 Miro-like protein AAA_17 PF13207.1 KKK27321.1 - 0.027 15.3 0.2 0.59 10.9 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.1 KKK27321.1 - 0.029 14.6 0.0 0.13 12.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 KKK27321.1 - 0.05 13.1 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Pro_isomerase PF00160.16 KKK27322.1 - 8.3e-41 139.7 0.0 1.5e-40 138.9 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD YjeF_N PF03853.10 KKK27322.1 - 4.5e-37 127.2 0.1 7.4e-37 126.5 0.1 1.4 1 0 0 1 1 1 1 YjeF-related protein N-terminus FDF PF09532.5 KKK27322.1 - 9.2e-12 45.4 0.8 9.2e-12 45.4 0.5 2.3 2 0 0 2 2 2 1 FDF domain Rtf2 PF04641.7 KKK27322.1 - 6e-05 22.3 0.0 0.00015 21.0 0.0 1.6 1 0 0 1 1 1 1 Rtf2 RING-finger U-box PF04564.10 KKK27322.1 - 0.0046 16.9 1.5 0.017 15.0 0.0 2.7 4 0 0 4 4 4 1 U-box domain Glyco_transf_4 PF13439.1 KKK27322.1 - 0.13 11.9 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase Family 4 PP2C PF00481.16 KKK27323.1 - 2.2e-62 210.7 0.1 3.8e-50 170.6 0.2 3.1 3 0 0 3 3 3 2 Protein phosphatase 2C DUF1180 PF06679.7 KKK27323.1 - 0.0078 16.1 2.3 0.01 15.6 0.2 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1180) DEC-1_N PF04625.8 KKK27323.1 - 0.024 13.3 0.4 0.024 13.3 0.2 1.5 2 0 0 2 2 2 0 DEC-1 protein, N-terminal region PIF1 PF05970.9 KKK27324.1 - 3.9e-64 216.8 0.0 1.8e-49 168.6 0.0 2.1 1 1 1 2 2 2 2 PIF1-like helicase AAA_30 PF13604.1 KKK27324.1 - 1.9e-18 66.7 0.0 3.8e-18 65.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KKK27324.1 - 1.7e-07 31.4 0.0 5.4e-07 29.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.1 KKK27324.1 - 2.2e-05 24.4 0.2 0.00027 21.0 0.1 2.6 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_16 PF13191.1 KKK27324.1 - 5.4e-05 23.2 0.5 0.003 17.5 0.0 3.3 4 0 0 4 4 4 1 AAA ATPase domain Herpes_Helicase PF02689.9 KKK27324.1 - 0.00011 20.1 0.1 0.00058 17.7 0.0 1.9 2 0 0 2 2 2 1 Helicase AAA_19 PF13245.1 KKK27324.1 - 0.00015 21.4 0.0 0.00035 20.2 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain T2SE PF00437.15 KKK27324.1 - 0.00024 20.0 0.0 0.00059 18.8 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein DUF2075 PF09848.4 KKK27324.1 - 0.00074 18.5 1.6 0.0081 15.1 0.0 2.6 1 1 1 2 2 2 1 Uncharacterized conserved protein (DUF2075) RNA_helicase PF00910.17 KKK27324.1 - 0.0045 17.1 0.0 0.014 15.5 0.0 1.9 1 0 0 1 1 1 1 RNA helicase AAA PF00004.24 KKK27324.1 - 0.0067 16.6 0.0 0.016 15.4 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PhoH PF02562.11 KKK27324.1 - 0.0089 15.2 0.0 0.037 13.2 0.0 1.9 2 0 0 2 2 2 1 PhoH-like protein TrwB_AAD_bind PF10412.4 KKK27324.1 - 0.0096 14.5 0.0 0.018 13.6 0.0 1.4 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain UvrD-helicase PF00580.16 KKK27324.1 - 0.01 15.1 0.6 0.016 14.5 0.0 1.6 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain Arch_ATPase PF01637.13 KKK27324.1 - 0.011 15.3 0.2 0.037 13.7 0.1 1.8 1 1 0 1 1 1 0 Archaeal ATPase NB-ARC PF00931.17 KKK27324.1 - 0.015 14.1 0.0 0.026 13.3 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_14 PF13173.1 KKK27324.1 - 0.019 14.8 0.0 0.068 13.0 0.0 2.0 1 1 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.13 KKK27324.1 - 0.02 14.4 0.1 10 5.5 0.1 2.9 2 1 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_11 PF13086.1 KKK27324.1 - 0.021 14.4 3.6 0.031 13.8 0.0 2.8 3 1 0 3 3 3 0 AAA domain AAA_18 PF13238.1 KKK27324.1 - 0.024 14.9 0.3 0.88 9.8 0.0 2.7 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 KKK27324.1 - 0.038 13.6 0.0 0.098 12.3 0.0 1.7 2 0 0 2 2 1 0 NACHT domain DUF258 PF03193.11 KKK27324.1 - 0.068 12.3 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Sigma54_activat PF00158.21 KKK27324.1 - 0.077 12.4 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_7 PF12775.2 KKK27324.1 - 0.088 11.8 0.0 0.19 10.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region D3 MobB PF03205.9 KKK27324.1 - 0.12 12.0 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_5 PF07728.9 KKK27324.1 - 0.14 11.9 0.4 1.5 8.5 0.3 2.4 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA PF00004.24 KKK27325.1 - 5e-10 39.6 0.2 4.5e-06 26.9 0.0 2.5 1 1 1 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KKK27325.1 - 2.2e-08 34.2 0.0 3.8e-08 33.5 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_11 PF13086.1 KKK27325.1 - 0.00094 18.8 0.0 0.0012 18.4 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KKK27325.1 - 0.0015 18.2 0.0 0.0091 15.7 0.0 2.2 1 1 1 2 2 2 1 AAA domain (dynein-related subfamily) TIP49 PF06068.8 KKK27325.1 - 0.002 16.9 0.0 0.0027 16.4 0.0 1.1 1 0 0 1 1 1 1 TIP49 C-terminus AAA_19 PF13245.1 KKK27325.1 - 0.0024 17.6 0.0 0.012 15.3 0.0 2.1 2 0 0 2 2 2 1 Part of AAA domain NACHT PF05729.7 KKK27325.1 - 0.0034 17.0 0.0 0.0082 15.8 0.0 1.7 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.1 KKK27325.1 - 0.004 17.2 0.0 0.0063 16.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 KKK27325.1 - 0.0092 15.0 0.0 0.013 14.5 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus RNA_helicase PF00910.17 KKK27325.1 - 0.021 14.9 0.0 0.047 13.8 0.0 1.6 1 0 0 1 1 1 0 RNA helicase NB-ARC PF00931.17 KKK27325.1 - 0.039 12.8 0.0 0.066 12.0 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_25 PF13481.1 KKK27325.1 - 0.041 13.2 0.0 0.09 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 KKK27325.1 - 0.056 14.2 0.0 0.082 13.7 0.0 1.5 1 1 0 1 1 1 0 AAA domain ArgK PF03308.11 KKK27325.1 - 0.058 12.1 0.0 0.09 11.5 0.0 1.3 1 0 0 1 1 1 0 ArgK protein T2SE PF00437.15 KKK27325.1 - 0.072 11.9 0.0 0.13 11.1 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_18 PF13238.1 KKK27325.1 - 0.094 13.0 0.0 0.25 11.6 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_3 PF07726.6 KKK27325.1 - 0.12 12.0 0.0 0.25 10.9 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.10 KKK27325.1 - 0.14 11.9 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 NTPase FHA PF00498.21 KKK27326.1 - 1.6e-13 50.5 0.0 2.8e-13 49.7 0.0 1.5 1 0 0 1 1 1 1 FHA domain zf-RING_2 PF13639.1 KKK27326.1 - 6.4e-06 25.9 9.3 1.7e-05 24.5 6.5 1.8 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 KKK27326.1 - 0.0054 16.8 6.1 0.013 15.6 4.3 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 KKK27326.1 - 0.0063 16.2 6.3 0.015 15.0 4.4 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 KKK27326.1 - 0.044 13.6 2.8 0.1 12.4 1.9 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.20 KKK27326.1 - 0.074 12.7 7.6 0.19 11.3 5.3 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KKK27326.1 - 0.11 12.5 9.5 0.22 11.5 6.6 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.6 KKK27326.1 - 0.19 11.7 6.1 0.54 10.3 4.2 1.8 1 0 0 1 1 1 0 RING-like domain zf-C3HC4_4 PF15227.1 KKK27326.1 - 2.8 7.8 7.2 5.6 6.9 4.5 2.0 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-H2C2_2 PF13465.1 KKK27326.1 - 7.3 7.0 7.2 0.52 10.6 0.4 2.7 3 0 0 3 3 3 0 Zinc-finger double domain Arm PF00514.18 KKK27327.1 - 9.5e-69 225.1 30.7 6.5e-13 47.9 0.1 11.3 11 0 0 11 11 11 9 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 KKK27327.1 - 1.3e-23 83.0 14.3 6.9e-07 29.4 0.3 7.5 3 3 2 6 6 6 5 HEAT repeats HEAT PF02985.17 KKK27327.1 - 5.6e-20 69.5 14.5 0.047 13.7 0.1 9.7 10 0 0 10 10 10 5 HEAT repeat HEAT_EZ PF13513.1 KKK27327.1 - 5.6e-16 58.5 14.9 0.0019 18.6 0.1 8.2 7 2 2 9 9 9 6 HEAT-like repeat Arm_2 PF04826.8 KKK27327.1 - 8.9e-12 44.6 7.6 0.0035 16.4 0.0 3.3 2 1 1 3 3 3 3 Armadillo-like Adaptin_N PF01602.15 KKK27327.1 - 7.9e-11 40.9 8.3 7.2e-07 27.9 0.5 2.8 1 1 1 2 2 2 2 Adaptin N terminal region KAP PF05804.7 KKK27327.1 - 8.1e-11 40.5 0.5 1.8e-10 39.4 0.2 1.5 1 1 0 1 1 1 1 Kinesin-associated protein (KAP) V-ATPase_H_N PF03224.9 KKK27327.1 - 3.4e-09 36.2 2.1 0.00021 20.5 0.7 3.1 2 1 1 3 3 3 2 V-ATPase subunit H Vac14_Fab1_bd PF12755.2 KKK27327.1 - 0.0088 16.4 0.1 1.9 8.9 0.1 3.5 1 1 2 3 3 3 1 Vacuolar 14 Fab1-binding region RIX1 PF08167.7 KKK27327.1 - 0.011 15.3 0.3 0.21 11.2 0.2 2.9 2 0 0 2 2 2 0 rRNA processing/ribosome biogenesis HEAT_PBS PF03130.11 KKK27327.1 - 0.028 14.8 9.3 12 6.7 0.3 6.6 6 0 0 6 6 6 0 PBS lyase HEAT-like repeat Proteasom_PSMB PF10508.4 KKK27327.1 - 0.47 8.6 7.6 0.78 7.9 2.5 2.6 1 1 1 2 2 2 0 Proteasome non-ATPase 26S subunit Alb1 PF09135.6 KKK27328.1 - 3.8e-29 101.5 16.2 5.1e-29 101.1 11.2 1.2 1 0 0 1 1 1 1 Alb1 DUF4201 PF13870.1 KKK27328.1 - 0.0013 18.2 1.8 0.0016 17.9 1.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4201) F-protein PF00469.15 KKK27328.1 - 0.36 10.1 2.9 0.46 9.8 2.0 1.1 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef ABC_tran_2 PF12848.2 KKK27328.1 - 1.6 8.6 6.0 2.8 7.8 4.2 1.5 1 0 0 1 1 1 0 ABC transporter Vps16_N PF04841.8 KKK27329.1 - 7.4e-97 324.4 0.0 9.9e-97 324.0 0.0 1.1 1 0 0 1 1 1 1 Vps16, N-terminal region Vps16_C PF04840.7 KKK27329.1 - 1.1e-80 270.9 0.0 3.1e-80 269.5 0.0 1.6 2 0 0 2 2 2 1 Vps16, C-terminal region Bestrophin PF01062.16 KKK27331.1 - 4.1e-40 137.5 1.1 1.4e-39 135.7 0.7 1.7 1 1 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel PUL PF08324.6 KKK27332.1 - 1.9e-41 141.6 0.0 2.5e-41 141.2 0.0 1.2 1 0 0 1 1 1 1 PUL domain Peptidase_C97 PF05903.9 KKK27332.1 - 3.2e-41 140.5 0.0 5.2e-41 139.9 0.0 1.3 1 0 0 1 1 1 1 PPPDE putative peptidase domain Thioredoxin PF00085.15 KKK27332.1 - 3.7e-16 58.6 0.0 6.9e-16 57.8 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 KKK27332.1 - 0.00092 19.3 0.1 0.0047 17.1 0.1 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_3 PF13192.1 KKK27332.1 - 0.0027 17.4 0.1 0.0065 16.2 0.1 1.6 1 0 0 1 1 1 1 Thioredoxin domain TraF PF13728.1 KKK27332.1 - 0.0069 15.9 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 F plasmid transfer operon protein AhpC-TSA PF00578.16 KKK27332.1 - 0.011 15.3 0.0 0.021 14.5 0.0 1.4 1 0 0 1 1 1 0 AhpC/TSA family DUF2847 PF11009.3 KKK27332.1 - 0.012 15.2 0.0 0.022 14.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2847) Redoxin PF08534.5 KKK27332.1 - 0.036 13.6 0.1 0.086 12.3 0.1 1.6 1 0 0 1 1 1 0 Redoxin EF-hand_9 PF14658.1 KKK27333.1 - 0.00091 19.0 0.0 0.69 9.8 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.1 KKK27333.1 - 0.021 14.9 0.0 0.12 12.4 0.0 2.3 3 1 0 3 3 3 0 EF-hand domain pair EF-hand_8 PF13833.1 KKK27333.1 - 0.038 13.5 0.0 7.6 6.2 0.0 3.2 3 0 0 3 3 3 0 EF-hand domain pair UCH PF00443.24 KKK27334.1 - 7.5e-37 126.9 0.0 3.4e-36 124.7 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KKK27334.1 - 5.9e-11 42.3 0.0 1.5e-10 41.0 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-C3HC4_2 PF13923.1 KKK27335.1 - 0.00033 20.6 1.2 0.00033 20.6 0.8 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KKK27335.1 - 0.00099 18.7 4.3 0.0016 18.1 3.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain FYVE PF01363.16 KKK27335.1 - 0.012 15.5 3.3 0.019 14.8 2.3 1.3 1 0 0 1 1 1 0 FYVE zinc finger zf-RING_2 PF13639.1 KKK27335.1 - 0.099 12.4 2.7 0.18 11.6 1.9 1.5 1 0 0 1 1 1 0 Ring finger domain IBR PF01485.16 KKK27335.1 - 0.21 11.4 6.4 0.35 10.7 1.1 2.2 1 1 1 2 2 2 0 IBR domain zf-UBP PF02148.14 KKK27335.1 - 0.38 10.9 3.3 0.6 10.2 2.3 1.3 1 0 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein zf-C3HC4 PF00097.20 KKK27335.1 - 0.79 9.4 4.5 3.1 7.5 3.3 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-ribbon_3 PF13248.1 KKK27335.1 - 4.4 6.6 8.2 8.7 5.6 3.1 2.7 2 1 0 2 2 2 0 zinc-ribbon domain GTP_EFTU PF00009.22 KKK27336.1 - 3.1e-54 183.2 0.0 4.7e-54 182.6 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 KKK27336.1 - 4.4e-15 55.3 0.0 1e-14 54.1 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 KKK27336.1 - 8.4e-08 31.9 0.0 1.8e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 KKK27336.1 - 8.9e-08 32.1 0.0 3.5e-07 30.2 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_IV PF03764.13 KKK27336.1 - 0.0024 17.4 0.0 0.1 12.1 0.0 2.6 2 0 0 2 2 2 1 Elongation factor G, domain IV EXOSC1 PF10447.4 KKK27337.1 - 3.9e-28 97.2 0.2 5.9e-28 96.6 0.2 1.3 1 0 0 1 1 1 1 Exosome component EXOSC1/CSL4 ECR1_N PF14382.1 KKK27337.1 - 6.7e-13 47.6 0.1 1.1e-12 46.9 0.1 1.4 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region CRISPR_Cse2 PF09485.5 KKK27337.1 - 0.13 12.3 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 CRISPR-associated protein Cse2 (CRISPR_cse2) DUF4604 PF15377.1 KKK27338.1 - 8.5e-25 87.8 14.9 1.2e-24 87.3 10.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) F-box-like PF12937.2 KKK27339.1 - 0.00031 20.3 0.2 0.00073 19.2 0.2 1.7 1 0 0 1 1 1 1 F-box-like Asp PF00026.18 KKK27340.1 - 4.3e-71 239.7 6.3 6e-71 239.2 4.3 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 KKK27340.1 - 2.1e-07 31.3 0.8 0.021 15.2 0.0 2.8 2 1 0 2 2 2 2 Aspartyl protease TAXi_N PF14543.1 KKK27340.1 - 3.6e-05 23.7 0.0 0.0011 18.9 0.0 2.7 2 2 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 KKK27340.1 - 0.0038 16.7 0.0 0.015 14.8 0.0 2.0 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal Triabin PF03973.8 KKK27340.1 - 0.032 13.8 0.1 0.09 12.4 0.0 1.7 1 1 1 2 2 2 0 Triabin PPC PF04151.10 KKK27340.1 - 3 8.8 11.4 3.4 8.7 2.3 3.1 2 1 0 2 2 2 0 Bacterial pre-peptidase C-terminal domain Zn_clus PF00172.13 KKK27341.1 - 4.7e-07 29.5 14.8 7.2e-07 29.0 10.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 KKK27342.1 - 2.1e-18 66.1 12.6 2.1e-18 66.1 8.8 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily Nodulin-like PF06813.8 KKK27342.1 - 2.1e-09 37.0 1.0 2.1e-09 37.0 0.7 1.8 2 0 0 2 2 2 1 Nodulin-like PVL_ORF50 PF07768.6 KKK27342.1 - 1.6 8.7 6.5 0.1 12.6 0.8 1.8 2 0 0 2 2 2 0 PVL ORF-50-like family L51_S25_CI-B8 PF05047.11 KKK27343.1 - 4.9e-15 55.0 0.1 8.4e-15 54.2 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Ribosomal_L10 PF00466.15 KKK27344.1 - 9.9e-19 67.1 0.0 2.1e-18 66.0 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L10 U1snRNP70_N PF12220.3 KKK27345.1 - 4.2e-33 113.5 3.7 8.6e-33 112.5 2.6 1.5 1 0 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.17 KKK27345.1 - 6e-12 45.0 0.0 1.2e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KKK27345.1 - 1.3e-07 31.5 0.0 2.2e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KKK27345.1 - 0.0031 17.3 0.0 0.0099 15.7 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1777 PF08648.7 KKK27345.1 - 3.9 7.1 36.4 30 4.3 25.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1777) TIM PF00121.13 KKK27346.1 - 6.7e-90 300.4 0.6 7.5e-90 300.2 0.4 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase DeoRC PF00455.17 KKK27346.1 - 0.0015 18.2 0.5 0.83 9.2 0.1 2.9 1 1 1 3 3 3 2 DeoR C terminal sensor domain CutC PF03932.9 KKK27346.1 - 0.036 13.3 0.1 0.059 12.6 0.1 1.4 1 0 0 1 1 1 0 CutC family START PF01852.14 KKK27346.1 - 0.088 12.1 0.1 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 START domain DUF3722 PF12519.3 KKK27347.1 - 2.1e-83 279.5 5.5 2.9e-83 279.0 3.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3722) Prp19 PF08606.6 KKK27348.1 - 1.8e-33 114.0 1.8 3e-33 113.3 1.3 1.4 1 0 0 1 1 1 1 Prp19/Pso4-like WD40 PF00400.27 KKK27348.1 - 8.8e-17 60.2 0.1 4.2e-06 26.4 0.0 5.7 6 0 0 6 6 6 3 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 KKK27348.1 - 2.8e-09 36.3 0.2 3.5e-06 26.1 0.0 2.1 1 1 0 2 2 2 2 Coatomer WD associated region eIF2A PF08662.6 KKK27348.1 - 1.3e-06 28.2 0.1 0.0037 16.9 0.0 3.1 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A U-box PF04564.10 KKK27348.1 - 0.00031 20.6 0.0 0.00058 19.7 0.0 1.4 1 0 0 1 1 1 1 U-box domain PQQ_2 PF13360.1 KKK27348.1 - 0.00062 19.2 7.8 0.0043 16.5 1.4 2.4 1 1 1 2 2 2 2 PQQ-like domain Hira PF07569.6 KKK27348.1 - 0.01 15.0 0.0 2.3 7.4 0.0 3.2 2 1 1 3 3 3 0 TUP1-like enhancer of split PQQ PF01011.16 KKK27348.1 - 0.039 13.5 0.1 0.19 11.3 0.0 2.3 2 0 0 2 2 2 0 PQQ enzyme repeat DUF3312 PF11768.3 KKK27348.1 - 0.074 11.2 0.0 0.44 8.6 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3312) PalH PF08733.5 KKK27349.1 - 1.5e-104 349.6 0.0 5e-104 347.8 0.0 1.7 1 1 0 1 1 1 1 PalH/RIM21 HsbA PF12296.3 KKK27350.1 - 7.4e-24 83.9 12.3 7.4e-24 83.9 8.5 4.1 2 1 1 3 3 3 1 Hydrophobic surface binding protein A Syntaxin PF00804.20 KKK27350.1 - 0.57 10.3 4.0 1.4 9.1 0.3 2.9 1 1 1 3 3 3 0 Syntaxin CLASP_N PF12348.3 KKK27350.1 - 1.2 8.4 9.5 0.038 13.3 1.9 1.8 1 1 0 1 1 1 0 CLASP N terminal PALP PF00291.20 KKK27351.1 - 5e-21 75.2 0.0 3.7e-12 46.0 0.0 2.0 1 1 1 2 2 2 2 Pyridoxal-phosphate dependent enzyme LYTB PF02401.13 KKK27351.1 - 0.054 12.3 0.0 0.081 11.8 0.0 1.3 1 0 0 1 1 1 0 LytB protein DUF1399 PF07173.7 KKK27352.1 - 1.1e-19 71.0 0.3 9.7e-15 55.0 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF1399) Lar_restr_allev PF14354.1 KKK27352.1 - 0.026 14.8 1.0 0.088 13.1 0.1 2.2 2 0 0 2 2 2 0 Restriction alleviation protein Lar Glyco_hydro_16 PF00722.16 KKK27353.1 - 1.1e-40 138.9 5.3 1.1e-40 138.9 3.7 1.5 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 Laminin_G_3 PF13385.1 KKK27353.1 - 0.013 15.7 6.1 0.015 15.5 3.3 1.7 1 1 0 1 1 1 0 Concanavalin A-like lectin/glucanases superfamily DJ-1_PfpI PF01965.19 KKK27354.1 - 2.7e-19 69.0 0.1 4e-19 68.5 0.0 1.4 1 0 0 1 1 1 1 DJ-1/PfpI family DJ-1_PfpI_N PF13587.1 KKK27354.1 - 1.1e-14 53.6 0.0 2.5e-14 52.5 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of DJ-1_PfpI family p450 PF00067.17 KKK27356.1 - 4.3e-55 187.0 0.1 6.1e-55 186.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 SEN1_N PF12726.2 KKK27356.1 - 0.13 10.2 0.0 0.2 9.6 0.0 1.1 1 0 0 1 1 1 0 SEN1 N terminal BNR PF02012.15 KKK27357.1 - 1.4e-11 42.3 42.2 0.093 12.6 0.1 9.9 8 0 0 8 8 8 8 BNR/Asp-box repeat CBM_1 PF00734.13 KKK27357.1 - 1.9e-11 43.4 14.5 1.9e-11 43.4 10.1 2.2 2 0 0 2 2 2 1 Fungal cellulose binding domain TEX19 PF15553.1 KKK27357.1 - 0.049 13.5 0.1 0.097 12.5 0.0 1.4 1 0 0 1 1 1 0 Testis-expressed protein 19 DUF2452 PF10504.4 KKK27357.1 - 0.2 10.9 0.0 0.35 10.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2452) Sugar_tr PF00083.19 KKK27358.1 - 9.8e-127 423.2 28.9 1.1e-126 423.0 20.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KKK27358.1 - 1.1e-23 83.5 73.2 4.4e-22 78.2 27.5 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Phosphoesterase PF04185.9 KKK27359.1 - 1.6e-81 274.3 1.2 1.6e-81 274.3 0.8 1.7 2 0 0 2 2 2 1 Phosphoesterase family Fascin PF06268.8 KKK27359.1 - 1.9e-05 24.7 1.4 5.7e-05 23.1 0.2 2.1 1 1 1 2 2 2 1 Fascin domain Cytochrom_D1 PF02239.11 KKK27359.1 - 0.045 12.0 0.0 0.069 11.4 0.0 1.2 1 0 0 1 1 1 0 Cytochrome D1 heme domain Git3 PF11710.3 KKK27360.1 - 2.4e-24 86.0 8.4 2.4e-24 86.0 5.8 1.7 2 1 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 Git3_C PF11970.3 KKK27360.1 - 6.6e-09 35.4 1.3 1.3e-08 34.4 0.1 2.1 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 C-term 7tm_1 PF00001.16 KKK27360.1 - 1.3e-05 24.4 6.0 1.4e-05 24.4 3.5 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) GPDPase_memb PF10110.4 KKK27360.1 - 0.0022 17.4 0.3 0.0022 17.4 0.2 2.0 2 0 0 2 2 2 1 Membrane domain of glycerophosphoryl diester phosphodiesterase Dicty_CAR PF05462.6 KKK27360.1 - 0.0029 16.5 3.5 0.004 16.1 2.4 1.2 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor Con-6 PF10346.4 KKK27361.1 - 9.3e-37 124.1 11.6 1e-15 56.8 0.1 3.5 3 0 0 3 3 3 3 Conidiation protein 6 Replicase PF03090.12 KKK27361.1 - 0.00026 20.8 0.4 0.33 10.8 0.0 2.2 2 0 0 2 2 2 2 Replicase family SpoIIIAH PF12685.2 KKK27361.1 - 0.1 12.0 1.6 3.8 6.9 0.1 2.7 3 0 0 3 3 3 0 SpoIIIAH-like protein DUF3619 PF12279.3 KKK27361.1 - 0.61 10.1 5.9 0.21 11.6 0.5 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3619) DUF3359 PF11839.3 KKK27361.1 - 5.5 7.3 8.7 30 5.0 0.5 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3359) Asp PF00026.18 KKK27362.1 - 1.8e-73 247.5 13.2 2.2e-73 247.3 9.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 KKK27362.1 - 5.4e-06 26.8 1.5 0.00099 19.5 0.2 2.8 2 1 0 2 2 2 2 Aspartyl protease TAXi_N PF14543.1 KKK27362.1 - 5.9e-06 26.3 2.3 9.6e-06 25.6 0.6 2.0 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 KKK27362.1 - 0.072 12.6 0.0 0.2 11.2 0.0 1.9 2 0 0 2 2 2 0 Xylanase inhibitor C-terminal Het-C PF07217.6 KKK27363.1 - 6.2e-272 903.2 0.0 6.2e-272 903.2 0.0 1.9 2 0 0 2 2 2 1 Heterokaryon incompatibility protein Het-C Selenoprotein_S PF06936.6 KKK27364.1 - 3.9 6.9 17.1 0.17 11.4 6.9 2.2 3 0 0 3 3 3 0 Selenoprotein S (SelS) Clr5 PF14420.1 KKK27365.1 - 1.5e-20 72.8 2.7 4.8e-20 71.2 1.8 2.0 1 0 0 1 1 1 1 Clr5 domain DUF4047 PF13256.1 KKK27365.1 - 0.36 10.7 2.8 14 5.6 0.1 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4047) RNA_pol_N PF01194.12 KKK27366.1 - 6.6e-29 99.7 1.7 1.4e-28 98.6 1.2 1.6 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit XK-related PF09815.4 KKK27366.1 - 0.0062 15.5 0.0 0.01 14.8 0.0 1.2 1 0 0 1 1 1 1 XK-related protein Fer4_13 PF13370.1 KKK27366.1 - 0.15 12.4 2.5 9.8 6.6 0.0 3.9 3 2 1 4 4 4 0 4Fe-4S single cluster domain WD40 PF00400.27 KKK27367.1 - 6e-06 25.9 12.7 6.4e-05 22.6 0.0 5.5 7 0 0 7 7 7 2 WD domain, G-beta repeat FAD_binding_3 PF01494.14 KKK27368.1 - 2.5e-24 86.0 0.0 5.8e-23 81.5 0.0 2.1 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 KKK27368.1 - 2.7e-07 29.8 0.0 0.0021 17.0 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 KKK27368.1 - 0.00015 22.0 1.3 0.0019 18.5 0.0 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KKK27368.1 - 0.00021 20.3 0.1 0.004 16.1 0.0 2.5 3 0 0 3 3 3 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 KKK27368.1 - 0.00028 20.8 0.1 0.00074 19.4 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 KKK27368.1 - 0.00068 18.8 0.0 0.016 14.2 0.0 2.1 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase SE PF08491.5 KKK27368.1 - 0.00088 18.1 0.0 0.003 16.4 0.0 1.8 2 0 0 2 2 2 1 Squalene epoxidase Trp_halogenase PF04820.9 KKK27368.1 - 0.11 11.0 0.3 3.7 6.0 0.0 2.2 2 0 0 2 2 2 0 Tryptophan halogenase Pyr_redox_2 PF07992.9 KKK27368.1 - 0.18 11.6 0.0 0.35 10.7 0.0 1.6 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase CN_hydrolase PF00795.17 KKK27369.1 - 3.4e-26 91.7 0.0 4.8e-26 91.2 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase AAA_16 PF13191.1 KKK27370.1 - 3e-09 37.1 3.2 9.5e-09 35.4 0.1 3.3 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 KKK27370.1 - 3.9e-08 33.4 2.6 9.9e-08 32.1 0.0 3.1 3 0 0 3 3 3 1 AAA domain TPR_10 PF13374.1 KKK27370.1 - 6.3e-08 32.2 3.4 0.15 12.0 0.0 7.0 7 0 0 7 7 7 1 Tetratricopeptide repeat NACHT PF05729.7 KKK27370.1 - 7.7e-08 32.1 0.9 3.9e-07 29.8 0.0 2.7 2 1 0 2 2 2 1 NACHT domain TPR_12 PF13424.1 KKK27370.1 - 0.0001 22.1 23.2 1.6 8.7 0.1 8.9 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_2 PF07719.12 KKK27370.1 - 0.00051 19.7 3.9 23 5.2 0.1 7.1 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_7 PF13176.1 KKK27370.1 - 0.0016 18.0 0.4 1.7 8.6 0.0 4.9 4 0 0 4 4 4 1 Tetratricopeptide repeat AAA PF00004.24 KKK27370.1 - 0.0017 18.5 0.0 0.021 15.0 0.0 3.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 KKK27370.1 - 0.0058 16.3 0.0 0.031 14.0 0.0 2.3 1 0 0 1 1 1 1 Part of AAA domain ABC_tran PF00005.22 KKK27370.1 - 0.037 14.3 0.5 1.5 9.1 0.0 3.5 2 0 0 2 2 2 0 ABC transporter AAA_17 PF13207.1 KKK27370.1 - 0.099 13.4 0.0 0.42 11.4 0.0 2.2 1 0 0 1 1 1 0 AAA domain FAD_binding_4 PF01565.18 KKK27371.1 - 7.1e-31 106.5 5.1 1.2e-30 105.7 3.6 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KKK27371.1 - 9.5e-09 35.0 0.3 2.4e-08 33.7 0.2 1.7 1 0 0 1 1 1 1 Berberine and berberine like Aminotran_3 PF00202.16 KKK27372.1 - 7.2e-36 123.7 1.3 1.7e-32 112.6 0.9 2.9 1 1 0 1 1 1 1 Aminotransferase class-III MFS_1 PF07690.11 KKK27373.1 - 6.4e-09 34.9 15.0 8.2e-09 34.6 10.4 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF455 PF04305.9 KKK27374.1 - 1.1e-103 345.9 0.0 1.3e-103 345.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF455) Rieske PF00355.21 KKK27374.1 - 2.3e-06 27.0 0.0 5.1e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.1 KKK27374.1 - 0.0012 18.5 0.0 0.0049 16.5 0.0 2.1 2 1 0 2 2 2 1 Rieske-like [2Fe-2S] domain GST_N_3 PF13417.1 KKK27375.1 - 7.6e-07 29.2 0.0 4.2e-06 26.8 0.0 2.3 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KKK27375.1 - 0.00085 19.2 0.0 0.0022 17.9 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KKK27375.1 - 0.048 13.5 0.0 0.075 12.9 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Peptidase_A4 PF01828.12 KKK27376.1 - 1.9e-91 304.7 11.8 2.3e-91 304.5 8.2 1.1 1 0 0 1 1 1 1 Peptidase A4 family DUF1049 PF06305.6 KKK27376.1 - 0.049 13.1 0.1 0.085 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) Reprolysin_4 PF13583.1 KKK27377.1 - 0.047 13.2 0.2 0.13 11.7 0.1 1.7 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Tetraspannin PF00335.15 KKK27378.1 - 0.0014 17.9 0.1 0.0018 17.6 0.1 1.2 1 0 0 1 1 1 1 Tetraspanin family MARVEL PF01284.18 KKK27378.1 - 0.11 12.3 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Membrane-associating domain P5CR_dimer PF14748.1 KKK27379.1 - 1.2e-36 124.8 0.9 1.2e-36 124.8 0.7 1.8 2 1 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 KKK27379.1 - 5.3e-11 42.8 6.6 2.2e-05 24.7 0.2 2.7 1 1 1 2 2 2 2 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.18 KKK27379.1 - 5.9e-05 22.8 0.4 5.9e-05 22.8 0.3 2.2 1 1 1 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NMT1_2 PF13379.1 KKK27379.1 - 0.024 14.0 0.0 0.069 12.5 0.0 1.8 2 0 0 2 2 2 0 NMT1-like family ApbA PF02558.11 KKK27379.1 - 0.037 13.4 0.0 0.07 12.5 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.15 KKK27379.1 - 0.12 12.4 0.4 0.28 11.3 0.1 1.9 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase peroxidase PF00141.18 KKK27380.1 - 2.9e-89 298.5 0.0 7.2e-47 159.7 0.0 2.2 2 0 0 2 2 2 2 Peroxidase MFS_1 PF07690.11 KKK27381.1 - 2.3e-48 164.7 16.6 2.3e-48 164.7 11.5 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KKK27381.1 - 3.2e-12 45.7 6.4 3.2e-12 45.7 4.4 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_3 PF05977.8 KKK27381.1 - 0.5 8.4 11.9 0.0064 14.6 3.0 1.5 2 0 0 2 2 2 0 Transmembrane secretion effector OATP PF03137.15 KKK27381.1 - 0.66 7.9 9.3 0.61 8.0 0.3 3.0 3 0 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family PSDC PF12588.3 KKK27384.1 - 0.061 12.9 0.1 2.6 7.6 0.0 2.3 2 1 0 2 2 2 0 Phophatidylserine decarboxylase Glyco_hydro_31 PF01055.21 KKK27386.1 - 9.9e-81 271.8 8.2 8.3e-80 268.7 5.7 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 31 Acetyltransf_1 PF00583.19 KKK27386.1 - 0.0029 17.5 0.0 0.0065 16.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family GMC_oxred_N PF00732.14 KKK27387.1 - 2.7e-57 194.2 0.0 3.4e-57 193.8 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KKK27387.1 - 1.2e-38 132.6 0.0 2e-38 131.9 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 KKK27387.1 - 2e-08 33.5 0.4 3.4e-06 26.2 0.0 2.5 2 1 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KKK27387.1 - 6.7e-06 25.2 1.1 6.8e-05 21.8 0.2 2.1 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 KKK27387.1 - 5.9e-05 23.0 0.5 0.00018 21.4 0.4 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 KKK27387.1 - 0.00016 20.7 0.1 0.00027 19.9 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 KKK27387.1 - 0.00019 21.5 0.4 0.025 14.6 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KKK27387.1 - 0.00033 20.5 0.2 0.00065 19.6 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KKK27387.1 - 0.00053 19.1 0.2 0.0024 17.0 0.1 1.9 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.9 KKK27387.1 - 0.00062 18.3 0.2 0.001 17.6 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.17 KKK27387.1 - 0.0091 14.8 0.6 0.082 11.7 0.2 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A Trp_halogenase PF04820.9 KKK27387.1 - 0.021 13.4 0.6 0.05 12.2 0.2 1.7 2 0 0 2 2 2 0 Tryptophan halogenase NAD_binding_9 PF13454.1 KKK27387.1 - 0.066 12.9 0.1 0.13 12.0 0.1 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding TrkA_N PF02254.13 KKK27387.1 - 0.096 12.6 0.1 0.19 11.7 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain Pyr_redox PF00070.22 KKK27387.1 - 0.098 13.0 0.3 0.098 13.0 0.2 2.3 3 0 0 3 3 1 0 Pyridine nucleotide-disulphide oxidoreductase ELFV_dehydrog_N PF02812.13 KKK27387.1 - 0.11 12.0 0.1 0.92 9.0 0.0 2.2 2 0 0 2 2 2 0 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain FAD_oxidored PF12831.2 KKK27387.1 - 0.16 11.0 0.9 0.26 10.3 0.3 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase Myc_N PF01056.13 KKK27388.1 - 0.0062 15.7 0.4 0.0088 15.2 0.3 1.1 1 0 0 1 1 1 1 Myc amino-terminal region Ribosomal_L22e PF01776.12 KKK27388.1 - 0.073 13.0 0.1 0.75 9.8 0.0 2.3 2 0 0 2 2 2 0 Ribosomal L22e protein family Sulfatase PF00884.18 KKK27389.1 - 1.7e-22 80.0 0.4 3e-22 79.1 0.3 1.3 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 KKK27389.1 - 2.6e-06 27.0 0.3 4.3e-06 26.2 0.2 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.12 KKK27389.1 - 0.0038 15.6 0.0 0.0051 15.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Metalloenzyme PF01676.13 KKK27389.1 - 0.18 11.1 0.0 0.35 10.1 0.0 1.4 1 0 0 1 1 1 0 Metalloenzyme superfamily GMC_oxred_N PF00732.14 KKK27390.1 - 2.8e-28 98.9 0.0 1.3e-27 96.7 0.0 2.0 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KKK27390.1 - 6e-26 91.4 0.1 1.3e-25 90.4 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 KKK27390.1 - 1.2e-11 44.1 0.0 4.2e-05 22.5 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 KKK27390.1 - 1.1e-07 31.0 0.1 0.0015 17.5 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KKK27390.1 - 3.6e-06 27.0 0.0 7.4e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KKK27390.1 - 7e-06 25.9 0.0 1.9e-05 24.5 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 KKK27390.1 - 0.00011 22.3 1.4 0.026 14.5 0.3 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KKK27390.1 - 0.00012 21.2 0.1 0.00028 20.0 0.1 1.5 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 KKK27390.1 - 0.00036 19.1 0.0 0.0007 18.1 0.0 1.4 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.22 KKK27390.1 - 0.0004 20.7 0.0 0.36 11.2 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KKK27390.1 - 0.00042 19.5 0.0 0.31 10.0 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 KKK27390.1 - 0.0017 17.4 0.0 0.0029 16.6 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 KKK27390.1 - 0.013 14.4 0.0 0.02 13.8 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein SET PF00856.23 KKK27391.1 - 0.058 13.7 0.1 6.3 7.0 0.0 2.2 2 0 0 2 2 2 0 SET domain zf-MYND PF01753.13 KKK27391.1 - 0.88 9.5 8.7 1.6 8.6 6.0 1.4 1 0 0 1 1 1 0 MYND finger Methyltransf_31 PF13847.1 KKK27392.1 - 2.8e-15 56.2 0.0 3.6e-15 55.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KKK27392.1 - 6.2e-15 55.7 0.0 1e-14 55.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KKK27392.1 - 6.5e-13 48.7 0.0 9.4e-13 48.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KKK27392.1 - 3.6e-12 46.5 0.0 6.1e-12 45.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KKK27392.1 - 3.4e-11 43.4 0.0 6.5e-11 42.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KKK27392.1 - 1.5e-09 38.2 0.0 2.3e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KKK27392.1 - 5.1e-08 32.9 0.0 8e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KKK27392.1 - 5.4e-06 25.8 0.0 7.8e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_2 PF00891.13 KKK27392.1 - 7.4e-06 25.3 0.0 1e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase TehB PF03848.9 KKK27392.1 - 9e-05 21.7 0.0 0.00013 21.1 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB FtsJ PF01728.14 KKK27392.1 - 0.00015 21.7 0.0 0.00021 21.3 0.0 1.3 1 1 0 1 1 1 1 FtsJ-like methyltransferase CheR PF01739.13 KKK27392.1 - 0.0014 17.9 0.0 0.11 11.7 0.0 2.1 1 1 1 2 2 2 1 CheR methyltransferase, SAM binding domain NodS PF05401.6 KKK27392.1 - 0.0014 18.0 0.0 0.0025 17.2 0.0 1.4 1 1 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_32 PF13679.1 KKK27392.1 - 0.0025 17.4 0.0 0.0043 16.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 KKK27392.1 - 0.0094 15.4 0.0 0.017 14.6 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RrnaAD PF00398.15 KKK27392.1 - 0.017 14.1 0.0 0.025 13.6 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase CMAS PF02353.15 KKK27392.1 - 0.019 14.0 0.0 0.023 13.7 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase FmrO PF07091.6 KKK27392.1 - 0.026 13.5 0.0 0.039 12.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) Methyltransf_4 PF02390.12 KKK27392.1 - 0.065 12.2 0.0 0.098 11.6 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase