# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- Lyase_1 PF00206.20 KKK11803.1 - 2.1e-89 300.0 0.0 2.9e-89 299.6 0.0 1.2 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.6 KKK11803.1 - 9.1e-23 80.8 0.1 2.9e-22 79.2 0.0 1.9 2 0 0 2 2 2 1 Argininosuccinate lyase C-terminal Put_DNA-bind_N PF06971.13 KKK11804.1 - 0.053 13.5 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 Putative DNA-binding protein N-terminus Acyl_transf_3 PF01757.22 KKK11822.1 - 4e-14 52.4 26.1 9.3e-14 51.2 26.1 1.6 1 1 0 1 1 1 1 Acyltransferase family TOM13 PF08219.11 KKK11823.1 - 1.9e-35 120.7 0.0 4.4e-35 119.5 0.0 1.6 1 0 0 1 1 1 1 Outer membrane protein TOM13 60KD_IMP PF02096.20 KKK11823.1 - 1.4e-22 80.3 0.0 3.8e-22 79.0 0.1 1.6 2 0 0 2 2 2 1 60Kd inner membrane protein Sugar_tr PF00083.24 KKK11825.1 - 1.7e-47 162.3 21.9 4.3e-47 161.0 21.9 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKK11825.1 - 1.3e-20 73.6 30.3 1.5e-20 73.4 29.5 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Nse4_C PF08743.10 KKK11827.1 - 2.4e-34 117.4 0.0 6.4e-34 116.1 0.0 1.8 1 0 0 1 1 1 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.6 KKK11827.1 - 1.4e-16 60.3 0.0 3.2e-16 59.2 0.0 1.7 1 0 0 1 1 1 1 Binding domain of Nse4/EID3 to Nse3-MAGE Baculo_LEF5 PF04838.12 KKK11827.1 - 0.0065 16.5 0.1 0.92 9.5 0.0 2.5 2 1 0 2 2 2 2 Baculoviridae late expression factor 5 DUF4336 PF14234.6 KKK11828.1 - 2.4e-15 56.6 0.0 1.1e-10 41.2 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4336) Isy1 PF06246.12 KKK11829.1 - 2.6e-79 266.4 0.2 3e-79 266.2 0.2 1.0 1 0 0 1 1 1 1 Isy1-like splicing family YolD PF08863.10 KKK11829.1 - 0.0097 15.9 0.0 0.019 15.0 0.0 1.4 1 0 0 1 1 1 1 YolD-like protein MMR_HSR1 PF01926.23 KKK11830.1 - 4.9e-14 52.4 0.0 1.3e-13 51.0 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KKK11830.1 - 5.4e-07 29.7 0.1 1.3e-06 28.4 0.1 1.6 1 1 0 1 1 1 1 RsgA GTPase FeoB_N PF02421.18 KKK11830.1 - 1.7e-05 24.4 0.1 2.8e-05 23.7 0.1 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Septin PF00735.18 KKK11830.1 - 0.00071 18.9 0.0 0.0012 18.2 0.0 1.2 1 0 0 1 1 1 1 Septin AIG1 PF04548.16 KKK11830.1 - 0.0011 18.3 0.0 0.0018 17.6 0.0 1.3 1 0 0 1 1 1 1 AIG1 family AAA_18 PF13238.6 KKK11830.1 - 0.003 18.1 0.1 0.0093 16.5 0.1 1.9 2 0 0 2 2 1 1 AAA domain PduV-EutP PF10662.9 KKK11830.1 - 0.0069 16.1 0.4 1.2 8.9 0.0 3.3 3 1 0 3 3 3 1 Ethanolamine utilisation - propanediol utilisation Roc PF08477.13 KKK11830.1 - 0.014 15.6 0.0 0.04 14.1 0.0 1.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase MeaB PF03308.16 KKK11830.1 - 0.024 13.7 0.0 0.04 12.9 0.0 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Dynamin_N PF00350.23 KKK11830.1 - 0.024 14.7 0.1 0.33 11.0 0.0 2.5 1 1 1 2 2 2 0 Dynamin family AAA_16 PF13191.6 KKK11830.1 - 0.069 13.5 0.0 0.12 12.8 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain Arf PF00025.21 KKK11830.1 - 0.069 12.6 0.0 0.65 9.4 0.0 2.1 2 0 0 2 2 2 0 ADP-ribosylation factor family TniB PF05621.11 KKK11830.1 - 0.076 12.4 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein GTP_EFTU PF00009.27 KKK11830.1 - 0.08 12.5 0.1 0.5 9.9 0.0 2.3 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain SRPRB PF09439.10 KKK11830.1 - 0.11 11.9 0.0 0.23 10.9 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit NB-ARC PF00931.22 KKK11830.1 - 0.11 11.6 0.0 0.25 10.5 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain AAA_28 PF13521.6 KKK11830.1 - 0.14 12.4 0.0 0.41 10.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain PI3Ka PF00613.20 KKK11831.1 - 2.2e-59 200.0 0.1 3.6e-59 199.3 0.1 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 KKK11831.1 - 1.9e-43 149.1 0.0 1.8e-30 106.6 0.0 2.5 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.24 KKK11831.1 - 2.3e-30 105.3 0.0 3.9e-30 104.6 0.0 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 ThiF PF00899.21 KKK11832.1 - 1.8e-40 138.9 0.0 2.9e-40 138.2 0.0 1.2 1 0 0 1 1 1 1 ThiF family TrkA_N PF02254.18 KKK11832.1 - 0.01 16.1 0.1 0.027 14.7 0.1 1.7 1 0 0 1 1 1 0 TrkA-N domain Sacchrp_dh_NADP PF03435.18 KKK11832.1 - 0.019 15.2 0.4 0.37 11.1 0.2 2.5 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain UDPG_MGDP_dh_N PF03721.14 KKK11832.1 - 0.11 12.1 0.1 0.25 10.9 0.1 1.6 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Melibiase_2 PF16499.5 KKK11832.1 - 0.14 11.3 0.0 0.23 10.6 0.0 1.2 1 0 0 1 1 1 0 Alpha galactosidase A LapA_dom PF06305.11 KKK11832.1 - 0.16 11.8 0.0 0.38 10.6 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain MARVEL PF01284.23 KKK11833.1 - 1.3e-20 73.9 14.5 1.6e-20 73.6 14.5 1.1 1 0 0 1 1 1 1 Membrane-associating domain Phage_holin_5_2 PF16079.5 KKK11833.1 - 0.19 12.1 4.1 0.4 11.0 0.5 2.7 2 1 1 3 3 3 0 Phage holin family Hol44, in holin superfamily V GMC_oxred_N PF00732.19 KKK11834.1 - 7.5e-31 107.6 0.0 1.5e-30 106.6 0.0 1.5 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KKK11834.1 - 1.5e-15 58.0 0.5 2.4e-15 57.3 0.5 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.24 KKK11834.1 - 1.7e-09 37.8 1.2 0.00035 20.3 0.1 2.4 2 1 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KKK11834.1 - 7.7e-07 28.5 0.1 0.016 14.3 0.0 2.4 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KKK11834.1 - 2.7e-06 27.5 0.1 1.9e-05 24.8 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KKK11834.1 - 3.2e-06 26.6 0.1 0.0023 17.2 0.0 2.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KKK11834.1 - 5.7e-06 25.3 0.0 6.9e-05 21.7 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.6 KKK11834.1 - 0.0003 20.2 0.0 0.024 13.9 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KKK11834.1 - 0.00038 20.9 0.0 0.37 11.4 0.0 3.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KKK11834.1 - 0.0022 17.3 0.0 0.0033 16.7 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 KKK11834.1 - 0.0032 16.9 0.1 0.02 14.3 0.1 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KKK11834.1 - 0.0088 15.1 0.0 0.014 14.5 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 KKK11834.1 - 0.021 14.1 0.1 0.047 12.9 0.0 1.6 2 0 0 2 2 2 0 Thi4 family NAD_binding_9 PF13454.6 KKK11834.1 - 0.054 13.5 0.0 0.14 12.1 0.0 1.7 1 0 0 1 1 1 0 FAD-NAD(P)-binding Trp_halogenase PF04820.14 KKK11834.1 - 0.087 11.7 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Metallophos PF00149.28 KKK11835.1 - 1.3e-12 48.6 0.0 2.3e-12 47.8 0.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KKK11835.1 - 6.3e-06 26.5 0.5 2e-05 24.9 0.5 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.6 KKK11835.1 - 0.067 12.5 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Metallophosphoesterase, calcineurin superfamily DUF2509 PF10713.9 KKK11835.1 - 0.14 12.3 0.0 0.32 11.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2509) LCCL PF03815.19 KKK11836.1 - 3.4e-22 78.4 0.0 5.8e-22 77.6 0.0 1.3 1 0 0 1 1 1 1 LCCL domain GCP_C_terminal PF04130.13 KKK11837.1 - 1.3e-102 343.4 0.1 2.2e-102 342.7 0.1 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 KKK11837.1 - 3.5e-84 283.0 0.0 2e-83 280.6 0.0 2.0 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal E1-E2_ATPase PF00122.20 KKK11839.1 - 5.3e-38 130.3 0.7 5.3e-38 130.3 0.7 3.3 3 1 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 KKK11839.1 - 9.6e-18 65.2 0.6 3e-17 63.6 0.0 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KKK11839.1 - 6.2e-10 38.6 0.0 1.4e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KKK11839.1 - 0.0048 16.7 0.1 0.0095 15.7 0.1 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase RRM_1 PF00076.22 KKK11840.1 - 7.3e-43 144.3 0.0 4.2e-20 71.3 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KKK11840.1 - 4.5e-05 23.5 0.0 0.3 11.2 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 KKK11840.1 - 0.016 15.2 0.0 5.2 7.2 0.0 2.5 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 KKK11840.1 - 0.072 13.0 0.0 5.5 6.9 0.0 2.3 2 0 0 2 2 2 0 Occluded RNA-recognition motif Alg6_Alg8 PF03155.15 KKK11841.1 - 1.1e-131 440.2 17.8 1e-83 282.0 8.9 2.1 2 0 0 2 2 2 2 ALG6, ALG8 glycosyltransferase family COX17 PF05051.13 KKK11842.1 - 3.1e-22 78.7 6.7 3.6e-22 78.4 6.7 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) LRR_6 PF13516.6 KKK11843.1 - 1.7e-14 52.5 1.2 0.003 17.5 0.0 7.8 8 0 0 8 8 8 3 Leucine Rich repeat LRR_4 PF12799.7 KKK11843.1 - 3.5e-05 24.1 6.7 0.35 11.3 0.3 5.1 5 1 0 5 5 5 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KKK11843.1 - 0.01 15.6 7.0 0.8 9.5 0.0 4.7 4 1 0 4 4 4 0 Leucine rich repeat NOA36 PF06524.12 KKK11843.1 - 0.88 8.8 13.5 1.4 8.2 13.5 1.2 1 0 0 1 1 1 0 NOA36 protein Nop14 PF04147.12 KKK11843.1 - 2.4 6.2 23.0 3.2 5.8 23.0 1.1 1 0 0 1 1 1 0 Nop14-like family Drc1-Sld2 PF11719.8 KKK11843.1 - 4.3 6.8 14.9 5.8 6.4 14.9 1.1 1 0 0 1 1 1 0 DNA replication and checkpoint protein GOLD_2 PF13897.6 KKK11843.1 - 4.4 7.8 9.0 10 6.6 9.0 1.6 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking RNA_pol_Rpc4 PF05132.14 KKK11843.1 - 4.6 7.7 5.6 8.4 6.8 5.6 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 RNA_pol_3_Rpc31 PF11705.8 KKK11843.1 - 8.9 6.5 22.1 16 5.7 22.1 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 TFIIS_M PF07500.14 KKK11844.1 - 1.1e-27 96.7 1.0 1.8e-27 96.0 0.1 1.8 2 1 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.18 KKK11844.1 - 1.8e-18 66.1 5.9 2.9e-18 65.4 5.9 1.4 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.11 KKK11844.1 - 2.1e-10 40.5 0.3 2.1e-10 40.5 0.3 1.9 2 0 0 2 2 2 1 TFIIS helical bundle-like domain Baculo_LEF5_C PF11792.8 KKK11844.1 - 0.029 14.0 2.1 0.043 13.5 0.2 2.1 2 0 0 2 2 2 0 Baculoviridae late expression factor 5 C-terminal domain DUF4522 PF15022.6 KKK11844.1 - 0.061 13.6 3.0 3.2 8.0 0.4 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF4522) MRPL52 PF18699.1 KKK11844.1 - 0.49 10.6 0.1 0.49 10.6 0.1 2.6 3 0 0 3 3 3 0 Mitoribosomal protein mL52 DUF4615 PF15393.6 KKK11844.1 - 3.1 8.4 8.2 0.16 12.6 1.8 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4615) Pectinesterase PF01095.19 KKK11845.1 - 2.4e-25 88.9 1.1 2.4e-20 72.5 0.3 2.1 2 0 0 2 2 2 2 Pectinesterase Fungal_trans PF04082.18 KKK11847.1 - 2.1e-09 36.8 0.2 3.7e-09 36.0 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK11847.1 - 7.3e-08 32.4 11.2 1.7e-07 31.3 11.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldo_ket_red PF00248.21 KKK11848.1 - 9.4e-70 235.1 0.0 1.2e-69 234.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Fungal_trans_2 PF11951.8 KKK11850.1 - 0.021 13.6 1.6 0.14 10.9 0.6 2.1 2 0 0 2 2 2 0 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK11851.1 - 3.4e-05 23.9 12.5 5.9e-05 23.1 12.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DNA_ligase_A_N PF04675.14 KKK11851.1 - 0.15 12.4 0.0 0.36 11.1 0.0 1.6 1 0 0 1 1 1 0 DNA ligase N terminus DUF3112 PF11309.8 KKK11852.1 - 1.2e-10 41.3 2.6 3.4e-05 23.4 0.0 3.0 2 1 1 3 3 3 2 Protein of unknown function (DUF3112) YwiC PF14256.6 KKK11852.1 - 0.81 10.0 8.8 0.48 10.8 2.0 2.7 2 1 0 2 2 2 0 YwiC-like protein MerC PF03203.14 KKK11852.1 - 1.5 9.3 8.3 12 6.4 0.7 2.5 1 1 1 2 2 2 0 MerC mercury resistance protein Fungal_trans PF04082.18 KKK11853.1 - 2e-10 40.2 0.1 3.5e-10 39.4 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK11853.1 - 4.6e-07 29.8 10.1 4.6e-07 29.8 10.1 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 KKK11854.1 - 2.3e-23 82.7 18.7 4e-23 81.9 18.7 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1180 PF06679.12 KKK11854.1 - 0.013 15.9 0.2 0.022 15.2 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) TMEM132D_C PF15706.5 KKK11854.1 - 0.075 12.8 1.4 0.12 12.2 0.0 1.9 2 0 0 2 2 2 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term YoqO PF14037.6 KKK11854.1 - 0.077 13.5 0.7 0.2 12.2 0.2 1.9 2 0 0 2 2 2 0 YoqO-like protein Peptidase_M10 PF00413.24 KKK11854.1 - 0.12 12.2 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Matrixin DUF1772 PF08592.11 KKK11854.1 - 0.45 10.8 10.4 1.4 9.2 4.1 3.6 2 1 1 3 3 3 0 Domain of unknown function (DUF1772) TauD PF02668.16 KKK11855.1 - 1.9e-51 175.4 0.0 2.5e-51 175.0 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Clr5 PF14420.6 KKK11856.1 - 2.4e-06 27.7 0.1 6.1e-06 26.4 0.1 1.7 1 0 0 1 1 1 1 Clr5 domain Dyp_perox PF04261.12 KKK11857.1 - 1.9e-87 293.3 0.0 2.2e-87 293.1 0.0 1.0 1 0 0 1 1 1 1 Dyp-type peroxidase family DUF3224 PF11528.8 KKK11859.1 - 8.9e-24 83.7 0.1 1.1e-23 83.4 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3224) Goodbye PF17109.5 KKK11862.1 - 7.9e-38 129.6 0.0 7.9e-38 129.6 0.0 3.0 4 0 0 4 4 3 1 fungal STAND N-terminal Goodbye domain TPR_12 PF13424.6 KKK11862.1 - 5.2e-06 26.7 3.5 0.66 10.3 0.1 5.0 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 KKK11862.1 - 2.2e-05 24.3 2.7 0.2 12.0 0.0 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat NACHT PF05729.12 KKK11862.1 - 5.4e-05 23.2 0.0 0.00041 20.3 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 KKK11862.1 - 6.5e-05 23.4 0.0 0.00051 20.5 0.0 2.7 1 0 0 1 1 1 1 AAA ATPase domain TPR_7 PF13176.6 KKK11862.1 - 0.0001 22.0 1.6 0.17 12.0 0.0 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.6 KKK11862.1 - 0.00035 20.4 9.2 0.35 10.8 0.0 5.4 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 KKK11862.1 - 0.00043 20.2 9.8 0.0027 17.7 0.2 5.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 KKK11862.1 - 0.001 19.5 3.9 0.013 16.0 0.1 4.2 5 0 0 5 5 4 1 Tetratricopeptide repeat RPN7 PF10602.9 KKK11862.1 - 0.0073 16.0 3.8 0.56 9.9 0.3 3.5 3 0 0 3 3 3 1 26S proteasome subunit RPN7 TPR_14 PF13428.6 KKK11862.1 - 0.012 16.4 6.8 0.091 13.6 0.1 5.1 3 1 1 4 4 4 0 Tetratricopeptide repeat AAA_22 PF13401.6 KKK11862.1 - 0.014 15.7 0.0 0.14 12.4 0.0 2.8 2 1 0 2 2 2 0 AAA domain TPR_1 PF00515.28 KKK11862.1 - 0.016 15.0 6.3 0.024 14.4 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF2075 PF09848.9 KKK11862.1 - 0.016 14.4 0.3 0.1 11.8 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) DUF2786 PF10979.8 KKK11862.1 - 0.072 13.0 0.1 0.37 10.8 0.1 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2786) SNAP PF14938.6 KKK11862.1 - 1.7 8.0 10.0 0.97 8.8 1.8 3.1 3 0 0 3 3 3 0 Soluble NSF attachment protein, SNAP adh_short PF00106.25 KKK11863.1 - 6.6e-25 87.7 0.0 2.5e-23 82.6 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KKK11863.1 - 1.5e-11 44.3 0.0 2e-10 40.6 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KKK11863.1 - 2.8e-11 43.6 0.0 6e-11 42.6 0.0 1.5 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KKK11863.1 - 1.6e-05 24.2 0.0 2.4e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 KKK11863.1 - 0.00012 21.7 0.0 0.0013 18.2 0.0 2.4 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 KKK11863.1 - 0.029 14.4 0.1 0.072 13.1 0.0 1.6 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 KKK11863.1 - 0.051 13.8 0.0 0.1 12.8 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain TLP-20 PF06088.11 KKK11864.1 - 0.16 11.9 4.6 0.2 11.6 4.6 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Zip PF02535.22 KKK11864.1 - 6 6.0 5.3 5.9 6.0 5.3 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter MFS_1 PF07690.16 KKK11865.1 - 2.9e-52 177.8 26.7 2.9e-52 177.8 26.7 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KKK11865.1 - 3.4e-11 42.7 10.5 3.4e-11 42.7 10.5 2.9 3 0 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 KKK11865.1 - 2.5e-05 22.9 3.4 2.5e-05 22.9 3.4 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_5 PF05631.14 KKK11865.1 - 0.00011 21.3 5.4 0.00025 20.1 3.0 2.1 2 0 0 2 2 2 1 Sugar-tranasporters, 12 TM CPP1-like PF11833.8 KKK11865.1 - 0.38 10.4 3.8 1.4 8.6 3.8 1.9 1 0 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like MFS_1 PF07690.16 KKK11866.1 - 6.1e-43 147.1 51.7 6.1e-43 147.1 51.7 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily AA_permease PF00324.21 KKK11867.1 - 2.9e-109 365.8 37.4 3.6e-109 365.5 37.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KKK11867.1 - 1e-36 126.7 41.1 1.3e-36 126.4 41.1 1.1 1 0 0 1 1 1 1 Amino acid permease Tweety PF04906.13 KKK11867.1 - 0.75 8.4 3.9 1.3 7.6 3.9 1.3 1 0 0 1 1 1 0 Tweety Gp_dh_C PF02800.20 KKK11868.1 - 2.9e-58 195.9 0.0 4.3e-58 195.4 0.0 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 KKK11868.1 - 9e-32 109.4 0.1 1.8e-31 108.4 0.1 1.5 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 KKK11868.1 - 0.0009 19.4 0.0 0.0076 16.4 0.0 2.3 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus 2-Hacid_dh_C PF02826.19 KKK11868.1 - 0.0029 17.0 0.0 0.0055 16.1 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Sugar_tr PF00083.24 KKK11869.1 - 3.6e-98 329.4 26.5 4.4e-98 329.1 26.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKK11869.1 - 2.8e-27 95.6 58.2 1.5e-24 86.6 29.7 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KKK11869.1 - 0.0038 15.8 1.9 0.0038 15.8 1.9 3.0 3 1 0 3 3 3 2 MFS/sugar transport protein Trp_oprn_chp PF09534.10 KKK11869.1 - 0.027 14.3 5.5 0.079 12.7 1.1 2.6 2 1 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF1230 PF06799.11 KKK11869.1 - 0.57 10.3 3.5 12 6.0 0.2 2.6 2 0 0 2 2 2 0 Conserved in the green lineage and diatoms 27 p450 PF00067.22 KKK11870.1 - 5.7e-65 219.9 0.0 6.6e-65 219.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Abhydrolase_6 PF12697.7 KKK11871.1 - 3.6e-13 50.6 0.4 4.9e-13 50.2 0.4 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KKK11871.1 - 2.8e-06 26.8 0.0 4.1e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KKK11871.1 - 0.00023 20.9 0.0 0.00043 20.0 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold FA_hydroxylase PF04116.13 KKK11873.1 - 1.9e-21 76.8 12.2 1.9e-21 76.8 12.2 2.3 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily zf-RING_4 PF14570.6 KKK11902.1 - 1.2e-19 69.8 13.3 2e-19 69.1 13.3 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 KKK11902.1 - 1.5e-06 28.0 7.4 2.7e-06 27.1 7.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RRM_1 PF00076.22 KKK11902.1 - 2.3e-05 24.1 0.0 5.6e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RING_2 PF13639.6 KKK11902.1 - 0.0005 20.3 11.5 0.0011 19.3 11.5 1.6 1 0 0 1 1 1 1 Ring finger domain Baculo_IE-1 PF05290.11 KKK11902.1 - 0.00056 19.9 5.1 0.001 19.1 5.1 1.4 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) Prok-RING_4 PF14447.6 KKK11902.1 - 0.054 13.4 9.5 0.62 10.0 9.8 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 KKK11902.1 - 0.11 12.4 12.7 0.22 11.4 12.7 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DZR PF12773.7 KKK11902.1 - 0.58 10.2 9.8 26 4.9 10.5 2.5 1 1 1 2 2 2 0 Double zinc ribbon zf-RING_UBOX PF13445.6 KKK11902.1 - 2.4 8.2 10.8 5.4 7.1 10.8 1.6 1 0 0 1 1 1 0 RING-type zinc-finger Complex1_30kDa PF00329.19 KKK11903.1 - 3.7e-45 153.5 0.0 5.1e-45 153.0 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit P5CR_dimer PF14748.6 KKK11909.1 - 7.1e-35 119.4 1.1 7.1e-35 119.4 1.1 1.8 2 0 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 KKK11909.1 - 1.2e-10 41.8 6.7 5.5e-05 23.7 0.2 2.7 1 1 1 2 2 2 2 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.23 KKK11909.1 - 0.0066 16.4 0.5 0.016 15.2 0.1 1.8 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.16 KKK11909.1 - 0.037 13.7 0.5 0.068 12.8 0.2 1.6 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA LANC_like PF05147.13 KKK11909.1 - 0.13 10.8 0.0 0.17 10.4 0.0 1.1 1 0 0 1 1 1 0 Lanthionine synthetase C-like protein MFS_1 PF07690.16 KKK11911.1 - 1.4e-48 165.6 16.2 1.4e-48 165.6 16.2 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KKK11911.1 - 7.9e-12 44.8 6.1 7.9e-12 44.8 6.1 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_3 PF05977.13 KKK11911.1 - 0.0052 15.2 2.5 0.0098 14.3 2.5 1.4 1 0 0 1 1 1 1 Transmembrane secretion effector OATP PF03137.20 KKK11911.1 - 0.99 7.6 12.2 0.23 9.7 3.1 2.6 3 0 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family PH PF00169.29 KKK11912.1 - 0.12 12.9 0.0 0.91 10.1 0.0 2.4 2 1 0 2 2 2 0 PH domain Glyco_hydro_31 PF01055.26 KKK11914.1 - 2.2e-90 304.0 7.0 3.7e-90 303.2 7.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 peroxidase PF00141.23 KKK11915.1 - 2.8e-87 292.2 0.0 2.5e-45 154.9 0.0 2.2 2 0 0 2 2 2 2 Peroxidase Gemini_AL1_M PF08283.11 KKK11915.1 - 0.17 12.0 1.0 13 6.0 0.0 3.3 2 1 1 3 3 3 0 Geminivirus rep protein central domain Peptidase_A4 PF01828.17 KKK11916.1 - 3.8e-83 278.1 15.0 4.6e-83 277.8 15.0 1.1 1 0 0 1 1 1 1 Peptidase A4 family Fer4 PF00037.27 KKK11917.1 - 3.9e-14 51.8 15.9 3.6e-08 32.9 4.1 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 KKK11917.1 - 1.3e-12 48.1 10.4 2e-12 47.5 10.4 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 KKK11917.1 - 4.1e-11 43.6 7.8 1.7e-05 25.6 0.5 2.3 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_21 PF14697.6 KKK11917.1 - 4.5e-10 39.5 4.2 0.00011 22.2 0.4 2.1 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 KKK11917.1 - 8.1e-10 38.7 21.8 7.5e-07 29.2 12.4 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 KKK11917.1 - 1.5e-09 37.9 21.0 8.1e-08 32.3 10.8 1.7 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_8 PF13183.6 KKK11917.1 - 1.1e-08 35.4 2.3 0.00027 21.3 0.1 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 KKK11917.1 - 1.7e-06 27.9 17.5 0.00038 20.4 5.4 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_2 PF12797.7 KKK11917.1 - 4.9e-06 26.3 12.5 0.01 15.9 2.0 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 KKK11917.1 - 2.2e-05 24.6 11.4 0.00029 21.1 1.8 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 KKK11917.1 - 0.00012 22.5 12.0 0.019 15.5 1.9 2.3 1 1 2 3 3 3 3 4Fe-4S dicluster domain c-SKI_SMAD_bind PF08782.10 KKK11917.1 - 0.018 15.3 6.1 0.98 9.7 0.3 2.2 1 1 1 2 2 2 0 c-SKI Smad4 binding domain Fer4_13 PF13370.6 KKK11917.1 - 0.051 14.1 15.4 0.72 10.4 4.3 2.6 2 1 1 3 3 3 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_18 PF13746.6 KKK11917.1 - 0.064 13.5 9.3 1.3 9.2 1.5 2.2 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_3 PF12798.7 KKK11917.1 - 0.066 14.2 15.7 0.12 13.4 3.5 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain ETF_QO PF05187.13 KKK11917.1 - 0.088 12.9 5.7 0.44 10.7 0.5 2.2 1 1 1 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Fer4_22 PF17179.4 KKK11917.1 - 0.51 11.2 11.9 1.5 9.7 1.6 2.2 1 1 1 2 2 2 0 4Fe-4S dicluster domain SURF6 PF04935.12 KKK11918.1 - 2.6e-49 167.7 27.0 2.6e-49 167.7 27.0 4.7 2 1 0 2 2 2 1 Surfeit locus protein 6 RRP14 PF15459.6 KKK11918.1 - 8.5e-19 67.9 0.9 8.5e-19 67.9 0.9 8.0 6 2 1 7 7 7 1 60S ribosome biogenesis protein Rrp14 PP-binding PF00550.25 KKK11920.1 - 1.7e-10 41.1 0.1 2.3e-10 40.6 0.1 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 KKK11920.1 - 5.1e-06 26.6 0.1 6.3e-06 26.3 0.1 1.1 1 0 0 1 1 1 1 Acyl-carrier Ribosomal_S2 PF00318.20 KKK11921.1 - 5.9e-68 228.3 0.0 4e-67 225.6 0.0 1.9 1 1 0 1 1 1 1 Ribosomal protein S2 Rick_17kDa_Anti PF05433.15 KKK11922.1 - 1.3e-06 28.2 12.4 2.4e-06 27.3 12.4 1.5 1 0 0 1 1 1 1 Glycine zipper 2TM domain Gly-zipper_Omp PF13488.6 KKK11922.1 - 0.00047 20.1 8.0 0.00099 19.1 8.0 1.6 1 0 0 1 1 1 1 Glycine zipper DUF533 PF04391.12 KKK11922.1 - 0.0037 16.9 1.5 0.0037 16.9 1.5 2.5 2 1 0 2 2 2 1 Protein of unknown function (DUF533) DUF456 PF04306.13 KKK11922.1 - 0.0099 16.2 0.3 0.014 15.7 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF456) Lin-8 PF03353.15 KKK11922.1 - 0.29 10.7 8.2 0.31 10.6 8.2 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Gly-zipper_YMGG PF13441.6 KKK11922.1 - 4.1 7.2 17.7 5.6 6.8 16.8 1.7 1 1 0 1 1 1 0 YMGG-like Gly-zipper CDP-OH_P_transf PF01066.21 KKK11923.1 - 1.1e-14 54.9 1.7 1.1e-14 54.9 1.7 1.9 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase NR_Repeat PF14046.6 KKK11923.1 - 0.24 11.5 3.3 4.4 7.5 0.1 2.5 2 0 0 2 2 2 0 Nuclear receptor repeat DUF2523 PF10734.9 KKK11923.1 - 0.73 10.4 3.1 45 4.7 3.1 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2523) UQ_con PF00179.26 KKK11928.1 - 5.3e-39 133.1 0.0 6.6e-39 132.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KKK11928.1 - 0.034 14.4 0.3 0.068 13.5 0.3 1.7 1 1 0 1 1 1 0 RWD domain UFC1 PF08694.11 KKK11928.1 - 0.088 12.4 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 YL1 PF05764.13 KKK11928.1 - 4.6 7.3 7.1 5.5 7.0 7.1 1.2 1 0 0 1 1 1 0 YL1 nuclear protein ABC_tran PF00005.27 KKK11929.1 - 1.1e-53 181.5 0.0 3.9e-31 108.4 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KKK11929.1 - 4.9e-50 170.7 22.8 4.6e-33 115.1 6.1 2.9 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.19 KKK11929.1 - 9.1e-08 31.8 0.0 0.0022 17.5 0.0 3.8 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KKK11929.1 - 7.4e-06 26.0 0.1 0.1 12.4 0.0 3.5 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KKK11929.1 - 6.7e-05 22.9 2.6 0.11 12.4 0.1 3.5 3 1 0 3 3 3 2 RsgA GTPase MMR_HSR1 PF01926.23 KKK11929.1 - 9.3e-05 22.5 0.1 0.048 13.8 0.0 2.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_23 PF13476.6 KKK11929.1 - 9.4e-05 23.0 7.4 0.0018 18.8 0.1 3.1 3 0 0 3 3 2 2 AAA domain AAA_16 PF13191.6 KKK11929.1 - 0.00097 19.6 1.0 1.7 9.0 0.2 3.5 3 1 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 KKK11929.1 - 0.001 19.4 1.8 1.6 9.0 0.1 3.4 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KKK11929.1 - 0.0028 17.3 0.1 0.36 10.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KKK11929.1 - 0.0032 17.2 0.4 3.1 7.6 0.1 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF87 PF01935.17 KKK11929.1 - 0.0037 17.4 2.0 0.042 13.9 0.8 2.9 2 1 0 2 2 2 1 Helicase HerA, central domain IstB_IS21 PF01695.17 KKK11929.1 - 0.0061 16.3 0.4 1.4 8.7 0.0 3.0 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA PF00004.29 KKK11929.1 - 0.0062 17.0 1.1 0.7 10.3 0.1 3.3 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 KKK11929.1 - 0.01 15.1 0.5 1.3 8.3 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin T2SSE PF00437.20 KKK11929.1 - 0.014 14.5 0.0 0.15 11.1 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_7 PF12775.7 KKK11929.1 - 0.042 13.3 0.1 8.3 5.9 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_18 PF13238.6 KKK11929.1 - 0.081 13.5 0.4 18 5.9 0.0 3.1 3 0 0 3 3 2 0 AAA domain RNA_helicase PF00910.22 KKK11929.1 - 0.12 12.7 0.1 23 5.4 0.0 2.8 2 0 0 2 2 2 0 RNA helicase Adeno_IVa2 PF02456.15 KKK11929.1 - 0.16 10.7 0.2 0.47 9.2 0.0 1.7 2 0 0 2 2 2 0 Adenovirus IVa2 protein AAA_15 PF13175.6 KKK11929.1 - 0.17 11.5 2.0 0.66 9.6 0.0 2.7 3 0 0 3 3 2 0 AAA ATPase domain TrwB_AAD_bind PF10412.9 KKK11929.1 - 0.27 10.1 2.4 1.3 7.8 0.2 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain cobW PF02492.19 KKK11929.1 - 0.42 10.2 1.7 5.2 6.6 0.2 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 KKK11929.1 - 0.62 10.0 2.6 3.8 7.4 0.3 2.4 2 0 0 2 2 2 0 NACHT domain Beach PF02138.18 KKK11930.1 - 3.3e-121 403.9 0.3 2.8e-120 400.8 0.0 2.2 2 0 0 2 2 2 1 Beige/BEACH domain PH_BEACH PF14844.6 KKK11930.1 - 1.1e-12 47.9 0.0 3.2e-12 46.4 0.0 1.8 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH Laminin_G_3 PF13385.6 KKK11930.1 - 5.3e-07 29.9 0.0 1.1e-06 28.8 0.0 1.4 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily WD40 PF00400.32 KKK11930.1 - 7e-07 29.9 0.2 0.09 13.7 0.0 3.2 2 0 0 2 2 2 2 WD domain, G-beta repeat DUF4800 PF16057.5 KKK11930.1 - 0.08 12.2 3.5 0.16 11.2 3.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4800) Peptidase_S8 PF00082.22 KKK11931.1 - 2.7e-38 131.9 7.5 5.1e-38 131.0 7.5 1.4 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 KKK11931.1 - 4e-19 69.1 0.4 1.6e-18 67.2 0.2 2.0 2 0 0 2 2 2 1 Peptidase inhibitor I9 Ferritin_2 PF13668.6 KKK11932.1 - 3.7e-09 36.9 0.0 5.2e-09 36.4 0.0 1.1 1 0 0 1 1 1 1 Ferritin-like domain TAL_FSA PF00923.19 KKK11933.1 - 6.2e-95 317.8 0.2 7.1e-95 317.6 0.2 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase Sod_Cu PF00080.20 KKK11934.1 - 3.8e-47 160.0 3.3 4.4e-47 159.8 3.3 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Chlorovi_GP_rpt PF06598.11 KKK11934.1 - 0.36 10.9 2.9 1.2 9.2 0.3 2.4 2 0 0 2 2 2 0 Chlorovirus glycoprotein repeat SNase PF00565.17 KKK11935.1 - 1.2e-77 257.3 0.2 1.2e-24 86.9 0.0 5.7 6 0 0 6 6 6 5 Staphylococcal nuclease homologue TUDOR PF00567.24 KKK11935.1 - 5.8e-24 84.5 0.0 1.4e-23 83.2 0.0 1.7 1 0 0 1 1 1 1 Tudor domain SMN PF06003.12 KKK11935.1 - 0.0011 18.3 0.0 0.002 17.4 0.0 1.3 1 0 0 1 1 1 1 Survival motor neuron protein (SMN) Agenet PF05641.12 KKK11935.1 - 0.0089 16.5 0.1 0.052 14.0 0.1 2.3 1 0 0 1 1 1 1 Agenet domain zf-H2C2_2 PF13465.6 KKK11946.1 - 5.4e-06 26.6 12.1 1.6e-05 25.1 1.4 2.9 3 0 0 3 3 3 2 Zinc-finger double domain zf-Di19 PF05605.12 KKK11946.1 - 0.00022 21.4 4.7 0.00039 20.6 4.7 1.3 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 KKK11946.1 - 0.00026 21.6 15.0 0.017 15.9 5.6 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KKK11946.1 - 0.0019 18.4 4.8 0.078 13.3 1.2 2.3 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 KKK11946.1 - 0.034 14.6 14.5 0.11 12.9 7.1 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-met PF12874.7 KKK11946.1 - 0.75 10.3 5.0 4.2 7.9 0.8 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Inv-AAD PF18785.1 KKK11947.1 - 8e-46 155.1 0.0 1.1e-45 154.6 0.0 1.1 1 0 0 1 1 1 1 Invertebrate-AID/APOBEC-deaminase dCMP_cyt_deam_1 PF00383.23 KKK11947.1 - 1.9e-12 46.9 0.0 1e-11 44.6 0.0 2.1 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region APOBEC_N PF08210.11 KKK11947.1 - 6.6e-05 22.9 0.0 9.9e-05 22.3 0.0 1.4 1 1 0 1 1 1 1 APOBEC-like N-terminal domain SNAD4 PF18750.1 KKK11947.1 - 0.0047 17.0 0.0 0.008 16.3 0.0 1.3 1 0 0 1 1 1 1 Secreted Novel AID/APOBEC-like Deaminase 4 NAD1 PF18778.1 KKK11947.1 - 0.13 12.4 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 Novel AID APOBEC clade 1 MafB19-deam PF14437.6 KKK11947.1 - 0.13 12.0 0.0 0.25 11.1 0.0 1.6 1 1 0 1 1 1 0 MafB19-like deaminase DUF4551 PF15087.6 KKK11948.1 - 4.9 5.9 6.1 5.6 5.7 6.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Uricase PF01014.18 KKK11949.1 - 1e-77 258.7 2.1 7.4e-41 139.5 0.4 2.0 2 0 0 2 2 2 2 Uricase Mob_Pre PF01076.19 KKK11949.1 - 0.077 12.8 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Plasmid recombination enzyme Nup96 PF12110.8 KKK11950.1 - 9.5e-85 284.2 1.5 2e-84 283.2 1.3 1.6 2 0 0 2 2 2 1 Nuclear protein 96 MFS_1 PF07690.16 KKK11951.1 - 3.6e-51 174.1 26.1 1.5e-43 149.1 19.4 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KKK11951.1 - 1.4e-06 27.5 32.7 5e-06 25.6 13.0 3.6 3 1 1 4 4 4 3 Sugar (and other) transporter OATP PF03137.20 KKK11951.1 - 0.12 10.7 9.1 0.13 10.5 3.8 2.4 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Ribosomal_60s PF00428.19 KKK11951.1 - 6 7.5 8.0 0.31 11.7 2.3 1.8 2 0 0 2 2 2 0 60s Acidic ribosomal protein Trp_syntA PF00290.20 KKK11955.1 - 3.9e-93 311.0 0.0 6.5e-93 310.3 0.0 1.3 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.25 KKK11955.1 - 3.8e-42 144.7 0.6 6.9e-42 143.9 0.6 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme zf-C2H2 PF00096.26 KKK11982.1 - 1e-05 25.7 8.3 1.2e-05 25.5 1.1 3.0 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf-met PF12874.7 KKK11982.1 - 6.2e-05 23.2 0.3 0.00015 22.0 0.3 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 KKK11982.1 - 0.00052 20.3 6.8 0.21 12.1 1.4 2.6 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KKK11982.1 - 0.00079 19.6 0.2 0.0019 18.5 0.2 1.7 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 KKK11982.1 - 0.0011 19.6 0.5 0.0011 19.6 0.5 2.6 1 1 1 2 2 2 1 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KKK11982.1 - 0.0086 16.1 0.6 0.0086 16.1 0.6 2.5 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_2 PF12756.7 KKK11982.1 - 0.063 13.6 0.3 0.11 12.9 0.3 1.3 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) BCDHK_Adom3 PF10436.9 KKK11983.1 - 6.4e-46 156.2 0.2 1.7e-45 154.8 0.0 1.7 2 0 0 2 2 2 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 KKK11983.1 - 3.5e-06 27.5 0.0 1.2e-05 25.8 0.0 1.8 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 KKK11983.1 - 0.071 13.1 0.0 1.6 8.7 0.0 2.3 2 0 0 2 2 2 0 Histidine kinase-like ATPase domain SPC22 PF04573.12 KKK11984.1 - 8.5e-25 87.2 0.3 1.7e-12 47.2 0.2 2.3 2 1 0 2 2 2 2 Signal peptidase subunit Macoilin PF09726.9 KKK11984.1 - 0.022 13.4 2.8 0.022 13.3 2.8 1.1 1 0 0 1 1 1 0 Macoilin family Apt1 PF10351.9 KKK11984.1 - 0.25 10.2 5.5 0.29 9.9 5.5 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain EMP24_GP25L PF01105.24 KKK11985.1 - 1.1e-46 159.0 1.3 1.3e-46 158.8 1.3 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD USP7_ICP0_bdg PF12436.8 KKK11986.1 - 1.3e-87 293.1 0.1 9.1e-87 290.3 0.1 2.1 2 0 0 2 2 2 1 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.6 KKK11986.1 - 2.8e-71 239.5 0.2 5.9e-69 231.9 0.0 3.2 2 1 0 3 3 3 1 Ubiquitin-specific protease C-terminal UCH PF00443.29 KKK11986.1 - 6.1e-48 163.6 0.2 1.4e-47 162.4 0.1 1.6 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KKK11986.1 - 9.8e-22 77.9 0.0 2.7e-21 76.5 0.0 1.8 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.26 KKK11986.1 - 9.2e-08 32.2 0.1 2.6e-07 30.8 0.1 1.9 1 0 0 1 1 1 1 MATH domain Rad60-SLD PF11976.8 KKK11986.1 - 0.011 15.5 0.6 9.8 6.1 0.1 4.0 3 1 0 3 3 3 0 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 KKK11986.1 - 0.018 14.8 0.9 14 5.5 0.0 3.9 4 0 0 4 4 4 0 Ubiquitin family Peptidase_C98 PF15499.6 KKK11986.1 - 0.23 10.9 0.9 0.57 9.6 0.1 2.0 2 0 0 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase DnaJ_C PF01556.18 KKK11988.1 - 4e-39 134.1 0.1 5.4e-39 133.6 0.1 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KKK11988.1 - 3.5e-26 91.1 1.2 5.8e-26 90.4 1.2 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KKK11988.1 - 8e-16 58.2 17.9 1.4e-15 57.4 17.9 1.4 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.19 KKK11988.1 - 0.3 11.1 8.8 0.21 11.6 2.1 2.4 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF2614 PF11023.8 KKK11988.1 - 3.7 7.7 6.9 8.1 6.6 1.0 2.2 1 1 1 2 2 2 0 Zinc-ribbon containing domain zinc-ribbons_6 PF07191.12 KKK11988.1 - 6.5 6.8 6.5 9.6 6.3 1.5 2.2 1 1 1 2 2 2 0 zinc-ribbons Sulfate_transp PF00916.20 KKK11989.1 - 9.9e-109 363.6 21.3 1.3e-108 363.1 21.3 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 KKK11989.1 - 5.6e-08 32.4 0.0 1.1e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 KKK11989.1 - 0.00015 22.1 3.2 0.00015 22.1 3.2 3.4 2 1 1 3 3 3 2 Molybdate transporter of MFS superfamily SNN_transmemb PF09049.10 KKK11989.1 - 1.9 8.5 8.7 0.082 12.9 1.2 2.7 2 0 0 2 2 2 0 Stannin transmembrane URO-D PF01208.17 KKK11990.1 - 2.8e-129 431.2 0.0 3.1e-129 431.1 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) dCMP_cyt_deam_1 PF00383.23 KKK11991.1 - 7.5e-15 54.7 0.1 1.1e-14 54.1 0.1 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KKK11991.1 - 1.7e-12 47.3 0.1 2.2e-12 46.9 0.1 1.1 1 0 0 1 1 1 1 MafB19-like deaminase NAD1 PF18778.1 KKK11991.1 - 0.00021 21.4 0.1 0.0022 18.1 0.1 2.0 1 1 0 1 1 1 1 Novel AID APOBEC clade 1 SNAD4 PF18750.1 KKK11991.1 - 0.00035 20.7 0.0 0.0011 19.0 0.0 1.7 2 0 0 2 2 2 1 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC2 PF18772.1 KKK11991.1 - 0.00037 20.6 0.1 0.0076 16.3 0.1 2.0 1 1 0 1 1 1 1 APOBEC2 NAD2 PF18782.1 KKK11991.1 - 0.00072 19.7 0.0 0.0083 16.2 0.0 2.0 1 1 0 1 1 1 1 Novel AID APOBEC clade 2 APOBEC_N PF08210.11 KKK11991.1 - 0.003 17.5 0.1 0.0072 16.2 0.1 1.6 1 1 0 1 1 1 1 APOBEC-like N-terminal domain Bd3614-deam PF14439.6 KKK11991.1 - 0.014 15.5 2.4 0.048 13.7 0.9 2.0 1 1 1 2 2 2 0 Bd3614-like deaminase APOBEC3 PF18771.1 KKK11991.1 - 0.062 13.4 0.0 0.2 11.8 0.0 1.8 1 1 0 1 1 1 0 APOBEC3 XOO_2897-deam PF14440.6 KKK11991.1 - 0.14 12.3 0.2 0.34 11.0 0.1 1.6 1 1 0 1 1 1 0 Xanthomonas XOO_2897-like deaminase WD40 PF00400.32 KKK11992.1 - 0.0047 17.7 0.2 6.9 7.7 0.0 3.6 3 0 0 3 3 3 1 WD domain, G-beta repeat Biopterin_H PF00351.21 KKK11992.1 - 0.092 11.8 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Biopterin-dependent aromatic amino acid hydroxylase Ribosomal_L10 PF00466.20 KKK11993.1 - 1.5e-24 86.0 0.6 3.1e-24 85.0 0.3 1.6 2 0 0 2 2 2 1 Ribosomal protein L10 RL10P_insert PF17777.1 KKK11993.1 - 3.1e-23 81.5 0.1 7.6e-23 80.3 0.0 1.7 2 0 0 2 2 2 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_60s PF00428.19 KKK11993.1 - 4.4e-23 81.7 3.5 4.4e-23 81.7 3.5 2.1 2 0 0 2 2 2 1 60s Acidic ribosomal protein Sugar_tr PF00083.24 KKK11997.1 - 4.8e-113 378.4 27.8 5.8e-113 378.1 27.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKK11997.1 - 8.6e-23 80.8 33.2 1.5e-17 63.6 6.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily US6 PF17616.2 KKK11997.1 - 0.098 12.6 0.2 0.2 11.6 0.2 1.5 1 0 0 1 1 1 0 Viral unique short region 6 MFS_1 PF07690.16 KKK11998.1 - 7.1e-35 120.6 47.2 1e-30 106.9 22.8 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily SUIM_assoc PF16619.5 KKK11998.1 - 0.0042 17.1 4.0 0.0078 16.3 4.0 1.4 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 Imm57 PF15596.6 KKK11998.1 - 0.011 16.1 0.0 0.021 15.1 0.0 1.4 1 0 0 1 1 1 0 Immunity protein 57 UNC-93 PF05978.16 KKK11998.1 - 0.02 14.6 2.7 0.04 13.6 2.7 1.5 1 0 0 1 1 1 0 Ion channel regulatory protein UNC-93 Pex14_N PF04695.13 KKK11998.1 - 0.045 14.4 1.0 0.045 14.4 1.0 1.8 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4834 PF16118.5 KKK11998.1 - 0.13 13.2 0.0 2.6 9.1 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) DUF2722 PF10846.8 KKK11998.1 - 0.16 10.9 3.7 0.22 10.4 3.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Spt20 PF12090.8 KKK11998.1 - 0.33 10.5 8.7 0.49 10.0 8.7 1.2 1 0 0 1 1 1 0 Spt20 family FPN1 PF06963.12 KKK11998.1 - 3.5 6.1 8.9 0.39 9.2 3.6 2.1 2 0 0 2 2 2 0 Ferroportin1 (FPN1) zf-CCHC PF00098.23 KKK11999.1 - 4.4e-52 171.9 96.1 7.5e-07 29.0 0.7 11.3 11 0 0 11 11 11 11 Zinc knuckle zf-CCHC_3 PF13917.6 KKK11999.1 - 1e-11 44.6 68.3 0.042 13.8 1.5 10.4 3 3 7 10 10 10 9 Zinc knuckle zf-CCHC_4 PF14392.6 KKK11999.1 - 9.2e-09 34.9 66.6 0.0071 16.0 0.7 11.1 11 0 0 11 11 11 9 Zinc knuckle zf-CCHC_2 PF13696.6 KKK11999.1 - 5.4e-06 26.1 87.6 0.00094 19.0 0.9 11.1 11 0 0 11 11 11 7 Zinc knuckle zf-CCHC_6 PF15288.6 KKK11999.1 - 8.2e-05 22.4 0.7 8.2e-05 22.4 0.7 10.0 9 2 1 10 10 10 6 Zinc knuckle Pkinase PF00069.25 KKK12000.1 - 0.0084 15.5 0.0 0.011 15.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain HpcH_HpaI PF03328.14 KKK12001.1 - 2.6e-39 134.7 0.0 1.7e-38 132.0 0.0 1.9 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.6 KKK12001.1 - 3.5e-12 46.1 0.0 4.6e-06 26.0 0.0 2.1 2 0 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold DUF846 PF05832.12 KKK12002.1 - 3.2e-48 163.3 10.4 4.1e-48 163.0 10.4 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) TMEM220 PF15071.6 KKK12002.1 - 0.1 13.4 1.7 0.11 13.3 0.4 1.7 2 0 0 2 2 2 0 Transmembrane family 220, helix AstE_AspA PF04952.14 KKK12002.1 - 0.21 10.6 0.0 0.29 10.2 0.0 1.1 1 0 0 1 1 1 0 Succinylglutamate desuccinylase / Aspartoacylase family SNARE_assoc PF09335.11 KKK12003.1 - 7.6e-12 45.8 3.3 7.6e-12 45.8 3.3 2.7 2 1 1 3 3 3 1 SNARE associated Golgi protein TMEMspv1-c74-12 PF11044.8 KKK12003.1 - 0.0047 16.9 0.2 0.013 15.5 0.2 1.7 1 0 0 1 1 1 1 Plectrovirus spv1-c74 ORF 12 transmembrane protein Patched PF02460.18 KKK12003.1 - 0.079 11.0 0.2 0.16 10.0 0.2 1.4 1 0 0 1 1 1 0 Patched family Pox_RNA_Pol_19 PF05320.12 KKK12003.1 - 0.96 9.4 9.1 29 4.6 10.3 2.1 2 0 0 2 2 2 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit NOA36 PF06524.12 KKK12003.1 - 4.4 6.6 10.8 6.3 6.0 10.8 1.2 1 0 0 1 1 1 0 NOA36 protein E7 PF00527.18 KKK12003.1 - 5.2 7.3 5.8 11 6.3 5.8 1.5 1 0 0 1 1 1 0 E7 protein, Early protein DUF1771 PF08590.10 KKK12004.1 - 5e-15 55.6 11.2 5e-15 55.6 11.2 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) Smr PF01713.21 KKK12004.1 - 6.4e-09 36.1 0.1 2.5e-08 34.2 0.1 2.1 1 0 0 1 1 1 1 Smr domain zf_CCCH_4 PF18345.1 KKK12004.1 - 9.3e-08 31.9 9.4 2.1e-05 24.4 1.2 2.9 2 1 0 2 2 2 2 Zinc finger domain zf-CCCH PF00642.24 KKK12004.1 - 2.9e-06 27.1 3.0 0.0045 16.9 0.1 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 KKK12004.1 - 7.7e-05 23.0 4.8 0.074 13.5 0.5 2.4 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 KKK12004.1 - 0.00017 21.8 2.3 0.25 11.6 0.0 2.4 1 1 1 2 2 2 2 Zinc-finger containing family zf-CCCH_4 PF18044.1 KKK12004.1 - 0.00021 21.0 12.2 0.004 16.9 1.4 3.1 2 1 0 2 2 2 2 CCCH-type zinc finger Torus PF16131.5 KKK12004.1 - 0.12 13.1 2.8 3.3 8.4 0.4 2.5 1 1 1 2 2 2 0 Torus domain Pyr_redox_2 PF07992.14 KKK12006.1 - 2.4e-48 164.9 0.1 2.8e-48 164.6 0.1 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KKK12006.1 - 1.9e-17 63.5 0.0 1.2e-15 57.6 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KKK12006.1 - 2.1e-15 57.0 0.1 1.9e-12 47.6 0.0 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KKK12006.1 - 0.00011 21.5 0.1 0.00041 19.7 0.0 1.8 2 0 0 2 2 2 1 Thi4 family NAD_binding_7 PF13241.6 KKK12006.1 - 0.00064 20.1 0.0 0.1 13.0 0.0 2.6 2 1 0 2 2 2 1 Putative NAD(P)-binding NAD_binding_8 PF13450.6 KKK12006.1 - 0.00084 19.5 0.8 0.064 13.5 0.1 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 KKK12006.1 - 0.0042 16.3 0.0 0.61 9.2 0.0 3.0 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) GIDA PF01134.22 KKK12006.1 - 0.011 14.9 3.1 1.8 7.5 0.0 3.5 4 1 1 5 5 5 0 Glucose inhibited division protein A FAD_binding_3 PF01494.19 KKK12006.1 - 0.025 13.8 0.7 3.2 6.9 0.0 2.4 2 1 0 2 2 2 0 FAD binding domain DAO PF01266.24 KKK12006.1 - 0.039 13.5 4.7 4.7 6.7 0.0 3.6 2 2 1 4 4 4 0 FAD dependent oxidoreductase FAD_oxidored PF12831.7 KKK12006.1 - 0.042 13.2 0.5 0.33 10.3 0.1 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase Shikimate_DH PF01488.20 KKK12006.1 - 0.093 12.8 0.0 11 6.0 0.0 3.0 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.24 KKK12006.1 - 0.32 10.0 3.9 0.36 9.8 0.4 2.6 3 1 2 5 5 5 0 FAD binding domain Peptidase_S8 PF00082.22 KKK12007.1 - 4.7e-36 124.6 1.3 7.8e-36 123.9 1.3 1.3 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 KKK12007.1 - 1.6e-27 95.4 1.3 3.1e-27 94.4 1.3 1.5 1 0 0 1 1 1 1 Proprotein convertase P-domain S8_pro-domain PF16470.5 KKK12007.1 - 0.08 13.7 0.0 0.21 12.4 0.0 1.7 1 0 0 1 1 1 0 Peptidase S8 pro-domain PX PF00787.24 KKK12008.1 - 2.7e-19 69.2 0.4 6e-19 68.1 0.4 1.5 1 0 0 1 1 1 1 PX domain Vps5 PF09325.10 KKK12008.1 - 3e-14 53.1 6.9 5.3e-07 29.4 0.4 2.1 2 0 0 2 2 2 2 Vps5 C terminal like BAR PF03114.18 KKK12008.1 - 0.00057 19.6 3.7 0.043 13.4 3.7 2.4 1 1 0 1 1 1 1 BAR domain Sec34 PF04136.15 KKK12008.1 - 0.017 15.0 1.2 0.023 14.6 0.1 1.8 2 0 0 2 2 2 0 Sec34-like family Laminin_II PF06009.12 KKK12008.1 - 0.32 11.0 3.0 0.4 10.7 0.2 2.3 2 1 1 3 3 3 0 Laminin Domain II Occludin_ELL PF07303.13 KKK12008.1 - 0.38 11.5 3.3 3.5 8.4 0.0 3.2 3 0 0 3 3 3 0 Occludin homology domain DUF1664 PF07889.12 KKK12008.1 - 1.3 9.1 5.8 6.9 6.7 0.3 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Troponin PF00992.20 KKK12008.1 - 2.1 8.6 8.1 1.2 9.4 0.3 2.6 3 0 0 3 3 3 0 Troponin Amino_oxidase PF01593.24 KKK12009.1 - 7.3e-83 279.3 0.0 4e-72 243.9 0.0 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase SWIRM PF04433.17 KKK12009.1 - 4.2e-16 59.1 0.1 9e-16 58.0 0.1 1.5 1 0 0 1 1 1 1 SWIRM domain NAD_binding_8 PF13450.6 KKK12009.1 - 1.1e-07 32.0 0.1 2.4e-07 30.9 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KKK12009.1 - 0.00079 19.1 0.6 0.0021 17.7 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase HMG_box PF00505.19 KKK12009.1 - 0.00098 19.5 0.7 0.00098 19.5 0.7 2.8 1 1 1 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KKK12009.1 - 0.013 16.0 0.7 0.013 16.0 0.7 2.2 2 1 1 3 3 3 0 HMG-box domain Pyr_redox_2 PF07992.14 KKK12009.1 - 0.033 13.4 0.4 0.35 10.1 0.1 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HyaE PF07449.11 KKK12009.1 - 0.073 13.0 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE PhoD PF09423.10 KKK12010.1 - 0.0069 15.5 0.1 0.79 8.7 0.0 2.3 2 0 0 2 2 2 2 PhoD-like phosphatase Gln-synt_C PF00120.24 KKK12011.1 - 2.9e-15 56.1 0.0 5.2e-12 45.4 0.0 2.1 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 KKK12011.1 - 4.3e-13 48.8 0.0 8e-13 47.9 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain SKG6 PF08693.10 KKK12012.1 - 1.1e-07 31.2 5.6 1.1e-07 31.2 5.6 3.1 3 0 0 3 3 3 1 Transmembrane alpha-helix domain DcuC PF03606.15 KKK12012.1 - 0.0024 16.4 0.0 0.0036 15.8 0.0 1.2 1 0 0 1 1 1 1 C4-dicarboxylate anaerobic carrier Phage_holin_2_4 PF16082.5 KKK12012.1 - 0.025 14.3 0.9 0.025 14.3 0.9 2.5 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like RIFIN PF02009.16 KKK12012.1 - 0.033 14.1 0.0 0.033 14.1 0.0 2.4 2 1 1 3 3 3 0 Rifin Saf_2TM PF18303.1 KKK12012.1 - 0.069 12.7 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 SAVED-fused 2TM effector domain Utp14 PF04615.13 KKK12012.1 - 0.45 9.0 11.7 0.64 8.5 11.7 1.3 1 0 0 1 1 1 0 Utp14 protein Gemini_mov PF01708.16 KKK12012.1 - 0.7 9.7 0.0 0.7 9.7 0.0 2.4 2 1 0 2 2 2 0 Geminivirus putative movement protein Macoilin PF09726.9 KKK12012.1 - 0.8 8.2 18.6 1.7 7.1 18.6 1.6 1 0 0 1 1 1 0 Macoilin family Endomucin PF07010.12 KKK12012.1 - 5.8 6.8 66.4 0.59 10.1 62.0 1.5 2 0 0 2 2 2 0 Endomucin Ndc1_Nup PF09531.10 KKK12012.1 - 7 5.2 18.4 10 4.7 18.4 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup RPN6_N PF18055.1 KKK12013.1 - 1.7e-31 109.0 10.2 4.6e-31 107.6 3.2 3.2 3 1 0 3 3 3 1 26S proteasome regulatory subunit RPN6 N-terminal domain PCI PF01399.27 KKK12013.1 - 1.4e-21 77.0 0.0 7.3e-21 74.7 0.1 2.2 2 1 0 2 2 2 1 PCI domain RPN6_C_helix PF18503.1 KKK12013.1 - 8.2e-10 38.2 1.8 1.1e-09 37.9 0.1 2.2 2 0 0 2 2 2 1 26S proteasome subunit RPN6 C-terminal helix domain DDRGK PF09756.9 KKK12013.1 - 1.4e-05 24.8 0.1 3.3e-05 23.6 0.1 1.5 1 0 0 1 1 1 1 DDRGK domain TPR_MalT PF17874.1 KKK12013.1 - 0.0057 16.1 4.9 0.0057 16.1 4.9 2.6 2 1 0 2 2 2 1 MalT-like TPR region TPR_12 PF13424.6 KKK12013.1 - 0.0086 16.3 23.9 0.031 14.6 4.4 5.3 6 0 0 6 6 6 2 Tetratricopeptide repeat HTH_Crp_2 PF13545.6 KKK12013.1 - 0.015 15.2 0.2 0.44 10.6 0.0 2.8 3 0 0 3 3 3 0 Crp-like helix-turn-helix domain DprA_WH PF17782.1 KKK12013.1 - 0.056 13.6 0.1 0.4 10.8 0.0 2.5 3 0 0 3 3 3 0 DprA winged helix domain Thioredoxin_12 PF18400.1 KKK12013.1 - 0.071 13.0 1.1 0.61 9.9 0.1 2.4 2 1 0 2 2 2 0 Thioredoxin-like domain DUF3496 PF12001.8 KKK12013.1 - 0.092 13.1 0.7 0.86 10.0 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3496) Prefoldin_2 PF01920.20 KKK12013.1 - 0.17 11.8 3.0 0.21 11.6 0.7 2.3 2 0 0 2 2 2 0 Prefoldin subunit TPR_14 PF13428.6 KKK12013.1 - 1.8 9.6 12.2 23 6.2 0.3 5.2 5 0 0 5 5 4 0 Tetratricopeptide repeat SbsC_C PF18058.1 KKK12013.1 - 8.8 6.6 10.0 0.65 10.2 0.5 2.7 2 1 1 3 3 3 0 SbsC C-terminal domain adh_short PF00106.25 KKK12014.1 - 3.5e-37 127.8 0.2 5.2e-37 127.2 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KKK12014.1 - 3.2e-27 95.6 0.0 4.4e-27 95.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KKK12014.1 - 1e-08 35.3 0.3 2e-08 34.4 0.3 1.4 1 1 0 1 1 1 1 KR domain DUF1776 PF08643.10 KKK12014.1 - 0.00032 20.2 0.1 0.00065 19.2 0.1 1.4 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) CTNNB1_binding PF08347.11 KKK12014.1 - 0.044 14.0 0.0 0.064 13.4 0.0 1.3 1 0 0 1 1 1 0 N-terminal CTNNB1 binding PRIMA1 PF16101.5 KKK12014.1 - 0.058 13.4 1.5 0.12 12.5 1.5 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 SWIB PF02201.18 KKK12015.1 - 9.8e-24 83.0 0.0 1.6e-23 82.3 0.0 1.4 1 0 0 1 1 1 1 SWIB/MDM2 domain Sof1 PF04158.14 KKK12016.1 - 8.7e-31 106.0 15.9 1.5e-30 105.3 15.9 1.4 1 0 0 1 1 1 1 Sof1-like domain WD40 PF00400.32 KKK12016.1 - 2.9e-28 97.5 1.9 7.7e-06 26.6 0.0 6.8 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKK12016.1 - 7.9e-09 35.7 0.2 0.24 11.7 0.0 4.3 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KKK12016.1 - 1.7e-05 23.9 0.0 0.0047 15.9 0.0 2.8 2 1 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein ADH_N PF08240.12 KKK12017.1 - 3e-25 88.2 4.0 6.3e-25 87.2 4.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KKK12017.1 - 5.2e-17 62.1 0.1 1.2e-16 60.9 0.1 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 KKK12017.1 - 0.00017 21.0 0.0 0.00028 20.3 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ComGG PF14173.6 KKK12017.1 - 0.18 12.2 0.0 9.5 6.7 0.0 2.2 1 1 1 2 2 2 0 ComG operon protein 7 WD40 PF00400.32 KKK12018.1 - 1e-27 95.8 10.7 2.3e-05 25.0 0.2 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat F-box-like PF12937.7 KKK12018.1 - 3.6e-12 46.0 0.1 7.6e-12 44.9 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KKK12018.1 - 2e-05 24.3 0.1 5.5e-05 22.9 0.1 1.8 1 0 0 1 1 1 1 F-box domain ANAPC4_WD40 PF12894.7 KKK12018.1 - 0.00078 19.7 0.0 5.2 7.5 0.0 4.1 1 1 4 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Elongin_A PF06881.11 KKK12018.1 - 0.0051 17.3 0.0 0.01 16.4 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A PQQ_2 PF13360.6 KKK12018.1 - 0.01 15.4 0.1 5.5 6.5 0.0 2.4 1 1 0 2 2 2 0 PQQ-like domain F-box_4 PF15966.5 KKK12018.1 - 0.011 15.6 0.0 0.022 14.6 0.0 1.5 1 0 0 1 1 1 0 F-box PQQ PF01011.21 KKK12018.1 - 0.011 15.6 0.2 26 5.0 0.1 3.7 3 0 0 3 3 3 0 PQQ enzyme repeat WD40_like PF17005.5 KKK12018.1 - 0.11 11.9 0.0 0.75 9.1 0.0 2.1 2 0 0 2 2 2 0 WD40-like domain ING PF12998.7 KKK12019.1 - 5.5e-07 30.1 0.0 1e-06 29.3 0.0 1.4 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 KKK12019.1 - 1.8e-05 24.6 9.9 3.4e-05 23.6 9.9 1.5 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 KKK12019.1 - 0.053 13.8 1.2 0.12 12.7 1.2 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain GFO_IDH_MocA PF01408.22 KKK12020.1 - 5.6e-08 33.6 0.2 2.6e-07 31.5 0.2 2.1 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold DHDPS PF00701.22 KKK12021.1 - 2.6e-30 105.1 0.0 1.2e-22 79.9 0.0 2.0 2 0 0 2 2 2 2 Dihydrodipicolinate synthetase family PEP_mutase PF13714.6 KKK12021.1 - 0.027 13.9 0.0 0.046 13.2 0.0 1.3 1 0 0 1 1 1 0 Phosphoenolpyruvate phosphomutase Pkinase PF00069.25 KKK12035.1 - 1.8e-19 70.1 0.0 3.6e-10 39.7 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KKK12035.1 - 1.1e-09 38.0 0.2 0.0033 16.7 0.0 3.4 4 0 0 4 4 4 3 Protein tyrosine kinase Kdo PF06293.14 KKK12035.1 - 0.073 12.4 0.1 0.17 11.2 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family DHO_dh PF01180.21 KKK12060.1 - 4.1e-63 213.4 0.1 1.4e-53 182.0 0.0 2.1 2 0 0 2 2 2 2 Dihydroorotate dehydrogenase NMO PF03060.15 KKK12060.1 - 0.017 14.5 0.1 0.027 13.8 0.1 1.2 1 0 0 1 1 1 0 Nitronate monooxygenase PcrB PF01884.17 KKK12060.1 - 0.031 13.7 0.5 5.9 6.3 0.1 2.3 2 0 0 2 2 2 0 PcrB family FMN_dh PF01070.18 KKK12060.1 - 0.082 11.9 0.3 2 7.4 0.5 2.6 2 1 0 2 2 2 0 FMN-dependent dehydrogenase TIM PF00121.18 KKK12061.1 - 7.7e-39 133.5 0.0 9.5e-39 133.2 0.0 1.1 1 0 0 1 1 1 1 Triosephosphate isomerase LacAB_rpiB PF02502.18 KKK12062.1 - 4.5e-41 140.1 0.0 5.1e-41 139.9 0.0 1.0 1 0 0 1 1 1 1 Ribose/Galactose Isomerase Gly_rich_SFCGS PF14272.6 KKK12062.1 - 0.0069 16.4 0.0 0.01 15.8 0.0 1.2 1 0 0 1 1 1 1 Glycine-rich SFCGS Exo70 PF03081.15 KKK12064.1 - 0.047 12.7 4.9 0.13 11.3 0.4 2.1 2 0 0 2 2 2 0 Exo70 exocyst complex subunit Syntaxin_2 PF14523.6 KKK12064.1 - 0.11 12.8 2.0 0.27 11.6 0.4 2.3 2 0 0 2 2 2 0 Syntaxin-like protein AATF-Che1 PF13339.6 KKK12064.1 - 1.1 9.9 11.6 0.28 11.8 3.0 3.0 2 1 0 2 2 2 0 Apoptosis antagonizing transcription factor Abhydrolase_6 PF12697.7 KKK12065.1 - 5.5e-06 27.1 0.0 8.6e-06 26.5 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.14 KKK12065.1 - 2.6e-05 23.9 0.1 6.3e-05 22.6 0.0 1.5 1 1 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 KKK12065.1 - 0.00019 21.3 0.0 0.00029 20.6 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Cutinase PF01083.22 KKK12065.1 - 0.099 12.6 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Cutinase Abhydrolase_8 PF06259.12 KKK12065.1 - 0.13 11.9 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase ECH_1 PF00378.20 KKK12066.1 - 6.8e-39 133.7 0.0 1.4e-38 132.6 0.0 1.5 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KKK12066.1 - 1e-27 97.5 0.0 1.2e-27 97.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase DUF883 PF05957.13 KKK12067.1 - 0.023 15.3 7.0 0.032 14.8 3.1 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) LEA_4 PF02987.16 KKK12067.1 - 0.047 13.8 5.0 0.047 13.8 5.0 3.4 1 1 2 3 3 3 0 Late embryogenesis abundant protein MLD PF11647.8 KKK12067.1 - 0.16 12.2 1.8 6.2 7.2 0.0 2.8 2 1 0 3 3 3 0 Membrane Localization Domain YtxH PF12732.7 KKK12067.1 - 0.41 11.2 11.4 41 4.8 11.4 2.2 1 1 0 1 1 1 0 YtxH-like protein NB-ARC PF00931.22 KKK12068.1 - 7.5e-13 48.3 0.0 1.2e-12 47.6 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.6 KKK12068.1 - 0.00021 21.6 0.0 0.00046 20.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KKK12068.1 - 0.0019 18.6 0.0 0.0047 17.3 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain ATPase PF06745.13 KKK12068.1 - 0.0039 16.6 0.1 0.013 14.9 0.0 1.7 2 0 0 2 2 2 1 KaiC AAA_33 PF13671.6 KKK12068.1 - 0.0041 17.3 0.0 0.011 15.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 KKK12068.1 - 0.033 13.5 0.0 0.11 11.7 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin RuvB_N PF05496.12 KKK12068.1 - 0.033 13.9 0.0 0.063 13.0 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain DUF397 PF04149.12 KKK12068.1 - 0.035 14.2 0.2 0.11 12.6 0.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF397) NACHT PF05729.12 KKK12068.1 - 0.044 13.7 0.0 0.091 12.7 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_18 PF13238.6 KKK12068.1 - 0.17 12.4 0.0 0.39 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain DnaJ PF00226.31 KKK12069.1 - 9.7e-07 28.8 1.1 2.6e-06 27.4 0.3 2.1 2 0 0 2 2 2 1 DnaJ domain DUF3974 PF13120.6 KKK12069.1 - 0.059 13.5 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3974) FHA PF00498.26 KKK12070.1 - 5.5e-12 45.9 0.0 1.1e-11 44.9 0.0 1.5 1 0 0 1 1 1 1 FHA domain Abhydrolase_3 PF07859.13 KKK12071.1 - 6e-42 143.9 0.0 1e-40 139.9 0.0 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KKK12071.1 - 1.6e-06 27.2 0.0 1.3e-05 24.2 0.0 2.0 1 1 0 1 1 1 1 Steryl acetyl hydrolase Pterin_4a PF01329.19 KKK12071.1 - 0.03 14.5 0.6 3.8 7.8 0.4 2.4 2 0 0 2 2 2 0 Pterin 4 alpha carbinolamine dehydratase COesterase PF00135.28 KKK12071.1 - 0.06 12.2 0.0 0.2 10.5 0.0 1.7 2 0 0 2 2 2 0 Carboxylesterase family GatB_N PF02934.15 KKK12072.1 - 3.5e-96 321.8 0.0 5.4e-96 321.2 0.0 1.3 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.18 KKK12072.1 - 3.2e-26 92.0 0.0 6.7e-26 90.9 0.0 1.5 1 0 0 1 1 1 1 GatB domain DUF3602 PF12223.8 KKK12075.1 - 9.1e-25 87.1 23.1 1.1e-21 77.2 3.6 2.9 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) DUF4502 PF14950.6 KKK12075.1 - 0.061 12.7 1.2 0.074 12.5 1.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4502) DUF2406 PF10295.9 KKK12076.1 - 7.5e-27 93.8 7.7 4.4e-26 91.4 0.0 3.5 3 0 0 3 3 3 1 Uncharacterised protein (DUF2406) Glypican PF01153.19 KKK12076.1 - 1.7 7.3 4.7 3.3 6.4 4.7 1.3 1 0 0 1 1 1 0 Glypican CDK2AP PF09806.9 KKK12076.1 - 6.5 6.7 11.9 0.72 9.9 5.6 2.1 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein Ribosomal_L35Ae PF01247.18 KKK12078.1 - 1.1e-41 140.9 0.3 1.3e-41 140.7 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 KKK12078.1 - 0.002 18.3 0.1 1.2 9.4 0.0 2.2 2 0 0 2 2 2 2 RimM N-terminal domain DUF2080 PF09853.9 KKK12078.1 - 0.015 15.0 0.8 0.12 12.1 0.1 2.1 1 1 1 2 2 2 0 Putative transposon-encoded protein (DUF2080) G6PD_C PF02781.16 KKK12079.1 - 1.4e-115 385.5 0.0 2.3e-115 384.8 0.0 1.3 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 KKK12079.1 - 1.8e-60 204.6 0.0 3.1e-60 203.8 0.0 1.4 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain DUF5617 PF18493.1 KKK12079.1 - 0.18 11.9 0.2 0.46 10.6 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5617) MFS_2 PF13347.6 KKK12080.1 - 5.8e-11 41.6 11.9 5.8e-11 41.6 11.9 2.0 2 0 0 2 2 2 1 MFS/sugar transport protein MFS_1_like PF12832.7 KKK12080.1 - 0.00027 19.9 1.7 0.001 18.0 1.6 2.1 1 1 0 1 1 1 1 MFS_1 like family FancD2 PF14631.6 KKK12080.1 - 0.07 10.5 0.0 3 5.1 0.0 2.0 2 0 0 2 2 2 0 Fanconi anaemia protein FancD2 nuclease DUF1708 PF08101.11 KKK12081.1 - 3.9e-171 570.0 0.0 6.3e-171 569.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1708) RhoGAP PF00620.27 KKK12081.1 - 0.011 15.6 0.0 0.045 13.6 0.0 1.9 2 0 0 2 2 2 0 RhoGAP domain Pkinase PF00069.25 KKK12082.1 - 1.1e-29 103.6 0.0 2.6e-29 102.4 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK12082.1 - 9.7e-09 34.9 0.0 0.0044 16.3 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 KKK12082.1 - 0.012 14.4 0.2 0.13 11.1 0.1 2.0 1 1 0 2 2 2 0 Fungal protein kinase SRF-TF PF00319.18 KKK12083.1 - 9.7e-24 82.6 0.2 1.5e-23 82.0 0.2 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) MFS_1 PF07690.16 KKK12084.1 - 5.5e-49 167.0 59.5 9.5e-49 166.2 56.9 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KKK12084.1 - 2.7e-16 59.2 20.6 1.3e-15 56.9 20.7 1.8 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KKK12084.1 - 1.3e-13 50.7 10.7 1.3e-13 50.7 10.7 3.2 2 1 0 3 3 3 2 Sugar (and other) transporter RrnaAD PF00398.20 KKK12085.1 - 0.00011 21.3 0.0 0.0002 20.6 0.0 1.4 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase DUF848 PF05852.11 KKK12085.1 - 0.048 13.8 1.6 0.082 13.0 1.6 1.3 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) ApbA_C PF08546.11 KKK12085.1 - 0.055 13.7 0.1 0.12 12.6 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA C terminal MSA-2c PF12238.8 KKK12085.1 - 0.39 10.7 14.7 0.26 11.3 6.5 3.2 3 0 0 3 3 3 0 Merozoite surface antigen 2c JAB PF01398.21 KKK12086.1 - 1.6e-15 57.1 0.0 3e-15 56.2 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease USP8_dimer PF08969.11 KKK12086.1 - 8.2e-10 38.9 0.2 1.5e-09 38.1 0.2 1.4 1 0 0 1 1 1 1 USP8 dimerisation domain Prok-JAB PF14464.6 KKK12086.1 - 5.8e-05 22.9 0.0 0.00016 21.4 0.0 1.7 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Polysacc_lyase PF14099.6 KKK12087.1 - 0.13 12.1 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide lyase FTHFS PF01268.19 KKK12088.1 - 1.1e-250 832.6 0.0 1.5e-250 832.2 0.0 1.2 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.19 KKK12088.1 - 1.1e-66 223.1 1.1 2.7e-66 221.8 1.1 1.7 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 KKK12088.1 - 2.4e-38 131.0 0.7 5.3e-38 129.9 0.7 1.6 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain OCD_Mu_crystall PF02423.15 KKK12088.1 - 0.0074 15.3 0.1 0.014 14.3 0.1 1.4 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family MBF1 PF08523.10 KKK12089.1 - 1.7e-24 86.1 0.6 1.7e-24 86.1 0.6 1.9 2 1 0 2 2 2 1 Multiprotein bridging factor 1 HTH_3 PF01381.22 KKK12089.1 - 3e-11 43.2 0.0 4.4e-11 42.7 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 KKK12089.1 - 0.00014 22.2 0.0 0.0003 21.1 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain WD40 PF00400.32 KKK12090.1 - 4.3e-27 93.8 1.9 7.2e-09 36.1 0.1 6.5 6 1 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKK12090.1 - 3.9e-10 39.9 0.1 0.019 15.2 0.1 5.7 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 KKK12090.1 - 9.1e-05 22.1 0.3 0.001 18.7 0.2 2.3 1 1 1 2 2 2 1 PQQ-like domain Nup160 PF11715.8 KKK12090.1 - 9.9e-05 21.2 0.1 0.00019 20.2 0.1 1.4 1 1 1 2 2 2 1 Nucleoporin Nup120/160 WD40_like PF17005.5 KKK12090.1 - 0.023 14.0 0.0 0.24 10.7 0.0 2.3 1 1 1 2 2 2 0 WD40-like domain Polyketide_cyc2 PF10604.9 KKK12091.1 - 3.4e-07 30.6 6.4 2.6e-06 27.8 6.4 2.4 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 KKK12091.1 - 0.003 17.8 2.0 0.0046 17.2 1.7 1.5 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport AHSA1 PF08327.11 KKK12091.1 - 0.0035 17.6 1.0 0.014 15.6 1.0 2.1 1 1 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein Pkinase PF00069.25 KKK12092.1 - 4.4e-13 49.2 0.0 6.7e-13 48.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK12092.1 - 3.9e-06 26.3 0.0 7.5e-06 25.4 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KKK12092.1 - 0.001 19.1 0.1 0.0017 18.3 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family eIF3m_C_helix PF18005.1 KKK12092.1 - 0.44 10.3 1.1 0.64 9.8 0.0 1.8 2 0 0 2 2 2 0 eIF3 subunit M, C-terminal helix Iso_dh PF00180.20 KKK12093.1 - 4e-72 243.3 0.0 4.8e-72 243.0 0.0 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF1304 PF06993.12 KKK12094.1 - 0.055 13.5 0.5 0.055 13.5 0.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1304) RRG8 PF17068.5 KKK12095.1 - 0.017 14.5 0.0 0.027 13.9 0.0 1.3 1 0 0 1 1 1 0 Required for respiratory growth protein 8 mitochondrial Hydrolase_6 PF13344.6 KKK12096.1 - 6.2e-31 106.5 0.0 1.2e-30 105.6 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KKK12096.1 - 4.2e-15 55.6 0.0 2.9e-14 52.9 0.0 2.1 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.26 KKK12096.1 - 1e-12 48.8 0.0 8.4e-06 26.2 0.0 2.9 1 1 2 3 3 3 3 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KKK12096.1 - 1.5e-06 28.4 0.1 0.022 14.9 0.0 2.5 2 1 1 3 3 3 2 Haloacid dehalogenase-like hydrolase Acid_phosphat_B PF03767.14 KKK12096.1 - 0.11 12.0 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) Rep_fac_C PF08542.11 KKK12097.1 - 6.8e-19 68.1 0.1 2.4e-18 66.3 0.1 2.0 1 0 0 1 1 1 1 Replication factor C C-terminal domain Sec20 PF03908.13 KKK12097.1 - 1.4e-16 60.1 1.0 1.4e-16 60.1 1.0 2.3 3 0 0 3 3 1 1 Sec20 AAA PF00004.29 KKK12097.1 - 2e-14 54.2 0.0 7.3e-14 52.3 0.0 2.1 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 KKK12097.1 - 7.9e-13 48.5 0.0 1.1e-11 44.8 0.0 2.5 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.15 KKK12097.1 - 6.7e-09 35.9 0.0 1.7e-08 34.6 0.0 1.7 1 1 0 1 1 1 1 Rad17 P-loop domain RuvB_N PF05496.12 KKK12097.1 - 3.7e-05 23.5 0.1 0.00013 21.8 0.0 2.0 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_assoc_2 PF16193.5 KKK12097.1 - 0.00019 21.7 1.4 0.00095 19.5 0.1 2.7 2 0 0 2 2 2 1 AAA C-terminal domain AAA_11 PF13086.6 KKK12097.1 - 0.00078 19.3 0.0 0.00078 19.3 0.0 3.1 3 1 0 3 3 3 1 AAA domain AAA_22 PF13401.6 KKK12097.1 - 0.00082 19.7 0.0 0.0085 16.4 0.0 2.6 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 KKK12097.1 - 0.00098 18.6 0.0 0.03 13.7 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 KKK12097.1 - 0.0032 17.9 0.0 0.0032 17.9 0.0 3.9 3 2 1 4 4 4 1 AAA ATPase domain AAA_24 PF13479.6 KKK12097.1 - 0.015 15.0 0.0 0.04 13.6 0.0 1.7 1 1 0 1 1 1 0 AAA domain DNA_pol3_delta PF06144.13 KKK12097.1 - 0.016 15.0 0.0 0.046 13.5 0.0 1.7 1 0 0 1 1 1 0 DNA polymerase III, delta subunit AAA_19 PF13245.6 KKK12097.1 - 0.018 15.4 0.0 0.096 13.0 0.0 2.2 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KKK12097.1 - 0.034 13.6 0.0 0.064 12.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_23 PF13476.6 KKK12097.1 - 0.041 14.4 8.5 0.091 13.3 0.0 3.3 2 1 0 2 2 1 0 AAA domain AAA_5 PF07728.14 KKK12097.1 - 0.047 13.7 0.1 0.48 10.4 0.1 2.5 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) DEAD PF00270.29 KKK12097.1 - 0.065 13.0 0.0 0.4 10.4 0.0 2.3 2 0 0 2 2 2 0 DEAD/DEAH box helicase AAA_18 PF13238.6 KKK12097.1 - 0.067 13.7 0.0 0.29 11.7 0.0 2.1 1 1 0 1 1 1 0 AAA domain ResIII PF04851.15 KKK12097.1 - 0.1 12.6 0.1 0.81 9.7 0.0 2.5 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit AAA_28 PF13521.6 KKK12097.1 - 0.26 11.5 2.8 0.64 10.2 0.0 2.9 2 1 0 3 3 3 0 AAA domain MutS_II PF05188.17 KKK12097.1 - 1 9.7 5.0 1.5 9.1 3.6 2.0 1 1 0 1 1 1 0 MutS domain II VMA21 PF09446.10 KKK12098.1 - 1.8e-10 40.7 18.2 7.6e-10 38.8 18.2 1.8 1 1 0 1 1 1 1 VMA21-like domain MS_channel PF00924.18 KKK12098.1 - 0.013 15.0 2.5 0.018 14.6 2.5 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel DUF2681 PF10883.8 KKK12098.1 - 0.016 15.6 0.2 0.025 15.0 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) Trp_oprn_chp PF09534.10 KKK12098.1 - 0.027 14.3 0.5 0.22 11.3 0.5 1.9 1 1 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Saf_2TM PF18303.1 KKK12098.1 - 0.069 12.7 0.1 0.093 12.3 0.1 1.2 1 0 0 1 1 1 0 SAVED-fused 2TM effector domain Vpu PF00558.19 KKK12098.1 - 0.14 11.9 0.9 0.22 11.3 0.0 1.6 2 0 0 2 2 2 0 Vpu protein Sugar_tr PF00083.24 KKK12099.1 - 3.8e-95 319.4 28.9 4.4e-95 319.2 28.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKK12099.1 - 2.4e-27 95.8 46.9 2.4e-24 85.9 21.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KKK12099.1 - 0.00059 18.4 1.6 0.00059 18.4 1.6 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) SNF2_N PF00176.23 KKK12100.1 - 3.4e-56 190.5 0.4 5.5e-56 189.8 0.4 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KKK12100.1 - 1.5e-19 70.4 0.6 1.3e-18 67.4 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KKK12100.1 - 1.3e-09 38.3 0.0 2.9e-09 37.2 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KKK12100.1 - 8.4e-06 25.7 0.0 1.9e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase ERCC3_RAD25_C PF16203.5 KKK12100.1 - 1e-05 24.9 0.1 2e-05 23.9 0.1 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase HHH_3 PF12836.7 KKK12100.1 - 0.011 16.0 0.0 0.025 14.8 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif HIGH_NTase1_ass PF16581.5 KKK12100.1 - 0.034 14.1 0.0 0.11 12.5 0.0 1.8 2 0 0 2 2 2 0 Cytidyltransferase-related C-terminal region CLP_protease PF00574.23 KKK12101.1 - 2.8e-76 255.5 0.0 3.5e-76 255.2 0.0 1.1 1 0 0 1 1 1 1 Clp protease Tugs PF17840.1 KKK12101.1 - 0.063 13.5 1.3 0.17 12.1 1.3 1.7 1 0 0 1 1 1 0 Tethering Ubl4a to BAGS domain Peptidase_S49 PF01343.18 KKK12101.1 - 0.071 13.1 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Peptidase family S49 Mito_carr PF00153.27 KKK12102.1 - 1e-45 153.6 5.8 3.5e-16 58.9 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein CBS PF00571.28 KKK12103.1 - 8.4e-06 26.1 0.0 0.53 10.8 0.0 3.3 2 1 1 3 3 3 3 CBS domain AIM24 PF01987.17 KKK12106.1 - 9.4e-52 175.7 0.1 1.2e-51 175.4 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 eIF-5_eIF-2B PF01873.17 KKK12107.1 - 2.9e-41 140.0 0.1 4.8e-41 139.3 0.1 1.3 1 0 0 1 1 1 1 Domain found in IF2B/IF5 TF_Zn_Ribbon PF08271.12 KKK12107.1 - 0.16 11.5 1.3 0.36 10.4 1.3 1.6 1 0 0 1 1 1 0 TFIIB zinc-binding Arc_trans_TRASH PF08394.10 KKK12107.1 - 1.2 9.5 7.5 1.2 9.6 0.4 2.8 1 1 1 2 2 2 0 Archaeal TRASH domain zf-HYPF PF07503.12 KKK12107.1 - 4.4 7.2 6.8 25 4.8 3.9 2.7 2 1 1 3 3 3 0 HypF finger adh_short PF00106.25 KKK12108.1 - 1.4e-18 67.0 0.0 3.6e-16 59.2 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KKK12108.1 - 6.3e-13 48.8 0.0 9e-09 35.2 0.0 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KKK12108.1 - 3.8e-06 26.9 0.0 5.7e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 KR domain EF-hand_1 PF00036.32 KKK12109.1 - 4e-21 72.9 5.7 7.3e-07 28.3 0.0 4.7 4 1 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 KKK12109.1 - 1.6e-20 71.2 1.2 7.1e-06 25.6 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.6 KKK12109.1 - 4.6e-20 71.8 0.4 1.1e-08 35.4 0.0 3.3 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_8 PF13833.6 KKK12109.1 - 6.2e-16 58.0 2.9 8.9e-08 31.9 0.0 3.8 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 KKK12109.1 - 3e-15 54.9 6.4 1.1e-05 24.7 0.3 4.1 4 1 0 4 4 4 3 EF hand RRM_1 PF00076.22 KKK12110.1 - 3e-21 75.0 0.0 4.1e-21 74.6 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KKK12110.1 - 0.025 14.4 0.0 0.048 13.5 0.0 1.5 1 1 0 1 1 1 0 Occluded RNA-recognition motif RRM_8 PF11835.8 KKK12110.1 - 0.058 13.6 0.0 0.08 13.2 0.0 1.2 1 0 0 1 1 1 0 RRM-like domain RRM_5 PF13893.6 KKK12110.1 - 0.11 12.0 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KKK12110.1 - 0.15 12.2 0.1 0.22 11.6 0.1 1.2 1 0 0 1 1 1 0 RNA binding motif ChaC PF04752.12 KKK12111.1 - 2.5e-44 151.5 0.2 1.5e-43 148.9 0.2 1.9 1 1 0 1 1 1 1 ChaC-like protein DUF4695 PF15766.5 KKK12111.1 - 0.12 12.7 2.0 0.21 11.8 2.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4695) SH3_1 PF00018.28 KKK12112.1 - 2.7e-14 52.5 0.0 4e-14 51.9 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KKK12112.1 - 1.9e-11 43.6 0.1 4.2e-11 42.5 0.0 1.6 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 KKK12112.1 - 1.1e-06 28.2 0.0 1.8e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain DUF2076 PF09849.9 KKK12112.1 - 1.9 8.5 7.6 0.33 11.0 3.7 1.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) Ank_2 PF12796.7 KKK12113.1 - 2.1e-35 121.2 10.0 5.4e-12 46.1 1.3 4.3 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KKK12113.1 - 9.9e-28 96.2 2.7 8.5e-09 35.8 0.0 5.0 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KKK12113.1 - 4.8e-22 75.7 2.1 0.0021 18.4 0.0 7.5 7 0 0 7 7 7 5 Ankyrin repeat Ank PF00023.30 KKK12113.1 - 7.7e-20 70.4 3.2 0.00025 21.3 0.1 7.2 7 0 0 7 7 7 4 Ankyrin repeat Ank_5 PF13857.6 KKK12113.1 - 4.2e-19 68.3 1.8 7.6e-07 29.3 0.0 5.2 2 1 3 5 5 5 4 Ankyrin repeats (many copies) SUIM_assoc PF16619.5 KKK12114.1 - 0.023 14.8 2.2 0.064 13.3 2.2 1.8 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 DEAD PF00270.29 KKK12115.1 - 2.9e-47 160.7 0.0 5.6e-47 159.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KKK12115.1 - 3.3e-24 85.3 0.0 1.8e-23 83.0 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 KKK12115.1 - 6.8e-20 71.1 0.0 2.3e-19 69.4 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 KKK12115.1 - 5.9e-06 26.4 0.0 5.9e-06 26.4 0.0 2.6 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_11 PF13086.6 KKK12115.1 - 1.5 8.5 0.0 1.5 8.5 0.0 3.4 3 0 0 3 3 3 0 AAA domain Ant_C PF05586.11 KKK12115.1 - 7.8 7.2 8.5 3.3 8.4 0.0 3.4 3 0 0 3 3 3 0 Anthrax receptor C-terminus region DnaJ PF00226.31 KKK12116.1 - 5.8e-14 52.0 2.8 1.1e-13 51.1 0.5 2.6 3 0 0 3 3 3 1 DnaJ domain VIR_N PF15912.5 KKK12116.1 - 1.3 8.5 4.9 1.7 8.2 4.9 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal Fungal_trans PF04082.18 KKK12117.1 - 4.4e-15 55.4 0.0 8.8e-15 54.5 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK12117.1 - 3.3e-07 30.3 12.1 6e-07 29.5 12.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ArfGap PF01412.18 KKK12120.1 - 8.2e-40 135.5 0.3 1.2e-39 135.0 0.3 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Meiotic_rec114 PF03525.14 KKK12121.1 - 4.2e-05 22.7 4.1 4.2e-05 22.7 4.1 2.6 2 2 0 2 2 2 2 Meiotic recombination protein rec114 zf_ZIC PF18366.1 KKK12122.1 - 0.0003 20.8 0.0 0.0008 19.5 0.0 1.7 1 0 0 1 1 1 1 Zic proteins zinc finger domain RFX_DNA_binding PF02257.15 KKK12122.1 - 0.026 15.1 0.0 0.051 14.2 0.0 1.4 1 0 0 1 1 1 0 RFX DNA-binding domain Arm PF00514.23 KKK12122.1 - 0.21 11.7 1.1 2.6 8.2 0.1 3.1 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat ORMDL PF04061.14 KKK12123.1 - 7.6e-59 197.4 3.7 8.9e-59 197.2 3.7 1.0 1 0 0 1 1 1 1 ORMDL family SelR PF01641.18 KKK12124.1 - 3e-50 169.4 0.1 3.7e-50 169.0 0.1 1.1 1 0 0 1 1 1 1 SelR domain Yippee-Mis18 PF03226.14 KKK12124.1 - 0.029 14.6 1.6 0.078 13.2 1.6 1.7 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zinc_ribbon_10 PF10058.9 KKK12124.1 - 0.061 13.1 1.5 1.2 8.9 0.0 2.3 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein CH PF00307.31 KKK12125.1 - 1.3e-13 51.1 0.0 2.3e-13 50.3 0.0 1.5 1 0 0 1 1 1 1 Calponin homology (CH) domain CDC24 PF06395.11 KKK12125.1 - 0.14 12.4 0.0 0.27 11.5 0.0 1.4 1 0 0 1 1 1 0 CDC24 Calponin CAMSAP_CH PF11971.8 KKK12125.1 - 0.15 12.0 0.0 0.32 10.9 0.0 1.5 1 0 0 1 1 1 0 CAMSAP CH domain Zip PF02535.22 KKK12126.1 - 0.18 11.0 0.4 0.25 10.5 0.4 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter DUF819 PF05684.12 KKK12126.1 - 0.21 10.6 0.0 0.34 9.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF819) Microvir_J PF04726.13 KKK12127.1 - 0.3 11.1 3.5 0.6 10.1 3.5 1.5 1 0 0 1 1 1 0 Microvirus J protein NDUFA12 PF05071.16 KKK12128.1 - 2.4e-13 50.7 4.0 5.7e-13 49.5 4.0 1.8 1 1 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 DUF5034 PF16437.5 KKK12130.1 - 0.033 14.2 0.0 0.064 13.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5034) Sars6 PF12133.8 KKK12130.1 - 0.15 12.0 0.1 0.36 10.8 0.1 1.6 1 0 0 1 1 1 0 Open reading frame 6 from SARS coronavirus HECT_2 PF09814.9 KKK12131.1 - 1.6e-104 349.8 0.1 1.8e-104 349.6 0.1 1.0 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding SAVED PF18145.1 KKK12131.1 - 0.082 12.7 0.6 0.16 11.7 0.6 1.4 1 0 0 1 1 1 0 SMODS-associated and fused to various effectors sensor domain TauD PF02668.16 KKK12132.1 - 4.7e-10 39.7 0.2 6.9e-09 35.9 0.1 1.9 1 1 1 2 2 2 2 Taurine catabolism dioxygenase TauD, TfdA family MFS_1 PF07690.16 KKK12134.1 - 6.6e-25 87.8 20.3 8.1e-25 87.5 20.3 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Kinesin PF00225.23 KKK12135.1 - 8.8e-58 195.8 0.0 1.4e-57 195.2 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KKK12135.1 - 1.4e-11 44.6 0.0 8.4e-10 38.8 0.0 2.4 2 0 0 2 2 2 1 Microtubule binding KLRAQ PF10205.9 KKK12135.1 - 0.014 15.6 0.9 0.014 15.6 0.9 2.5 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein Mto2_bdg PF12808.7 KKK12135.1 - 0.2 12.0 6.5 6.3 7.2 3.2 3.4 2 1 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region Pox_A_type_inc PF04508.12 KKK12135.1 - 0.23 11.4 6.5 0.052 13.4 1.4 2.7 2 1 1 3 3 3 0 Viral A-type inclusion protein repeat SIKE PF05769.11 KKK12135.1 - 0.35 10.8 10.2 1 9.3 10.2 1.7 1 1 0 1 1 1 0 SIKE family DivIC PF04977.15 KKK12135.1 - 1.8 8.4 6.1 28 4.6 0.1 2.8 2 0 0 2 2 2 0 Septum formation initiator KIAA1430 PF13879.6 KKK12135.1 - 3 8.7 7.0 6.1 7.7 2.0 2.7 2 1 0 2 2 2 0 KIAA1430 homologue YabA PF06156.13 KKK12135.1 - 3.4 8.3 9.6 17 6.1 0.4 2.6 1 1 1 2 2 2 0 Initiation control protein YabA RTA1 PF04479.13 KKK12136.1 - 6e-39 133.8 5.0 6e-39 133.8 5.0 1.3 2 0 0 2 2 2 1 RTA1 like protein ChAPs PF09295.10 KKK12137.1 - 2.1e-154 514.3 0.0 2.8e-154 513.9 0.0 1.1 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_14 PF13428.6 KKK12137.1 - 0.00015 22.3 3.0 0.3 12.0 0.0 4.7 3 3 2 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 KKK12137.1 - 0.00021 21.1 1.2 0.33 11.2 0.1 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 KKK12137.1 - 0.00028 20.6 0.1 4.3 7.3 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 KKK12137.1 - 0.0025 18.3 0.3 0.22 12.1 0.0 3.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 KKK12137.1 - 0.006 16.7 0.0 6.8 7.2 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_15 PF13429.6 KKK12137.1 - 0.017 14.3 2.8 0.99 8.5 0.7 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.6 KKK12137.1 - 0.041 14.0 0.3 4.3 7.5 0.0 3.0 2 1 1 3 3 3 0 Tetratricopeptide repeat DUF4129 PF13559.6 KKK12137.1 - 0.14 12.5 0.3 5 7.5 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4129) ANAPC3 PF12895.7 KKK12137.1 - 1.1 9.5 3.8 52 4.2 0.1 3.5 3 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 KKK12138.1 - 0.0021 17.7 5.0 0.0031 17.2 2.2 2.7 3 0 0 3 3 3 1 TPR repeat Choline_transpo PF04515.12 KKK12139.1 - 2.6e-81 273.4 26.2 2.6e-81 273.4 26.2 2.3 2 0 0 2 2 2 1 Plasma-membrane choline transporter RabGAP-TBC PF00566.18 KKK12139.1 - 1.9e-34 119.2 0.1 2.2e-30 105.9 0.1 2.7 2 1 0 2 2 2 2 Rab-GTPase-TBC domain Fructosamin_kin PF03881.14 KKK12139.1 - 0.0089 15.3 0.3 0.04 13.1 0.0 2.0 2 0 0 2 2 2 1 Fructosamine kinase DUF4106 PF13388.6 KKK12139.1 - 9.1 5.4 12.9 15 4.7 12.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) AAA PF00004.29 KKK12140.1 - 8.9e-48 162.1 0.0 5.5e-43 146.6 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KKK12140.1 - 2.8e-06 27.0 2.7 0.0072 16.1 0.0 2.9 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 KKK12140.1 - 0.00012 22.5 0.0 0.022 15.2 0.0 3.0 2 0 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 KKK12140.1 - 0.00014 21.6 0.0 0.00041 20.1 0.0 1.8 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Parvo_NS1 PF01057.17 KKK12140.1 - 0.00059 19.0 0.0 0.00098 18.3 0.0 1.2 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 RNA_helicase PF00910.22 KKK12140.1 - 0.0027 18.1 0.0 0.015 15.7 0.0 2.3 3 0 0 3 3 2 1 RNA helicase AAA_2 PF07724.14 KKK12140.1 - 0.004 17.3 0.0 0.0093 16.1 0.0 1.6 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) TIP49 PF06068.13 KKK12140.1 - 0.0074 15.5 0.0 0.012 14.8 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_22 PF13401.6 KKK12140.1 - 0.0085 16.4 0.0 0.044 14.1 0.0 2.2 1 1 1 2 2 2 1 AAA domain IstB_IS21 PF01695.17 KKK12140.1 - 0.0097 15.7 0.0 0.019 14.7 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_25 PF13481.6 KKK12140.1 - 0.011 15.3 0.0 0.041 13.5 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KKK12140.1 - 0.023 14.2 0.0 0.041 13.4 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Mg_chelatase PF01078.21 KKK12140.1 - 0.028 13.8 0.1 0.056 12.8 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 KKK12140.1 - 0.041 14.4 0.0 0.12 13.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 KKK12140.1 - 0.043 13.2 0.0 0.084 12.2 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_5 PF07728.14 KKK12140.1 - 0.046 13.7 0.0 0.13 12.2 0.0 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) PhoH PF02562.16 KKK12140.1 - 0.072 12.5 0.0 0.21 11.0 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein TsaE PF02367.17 KKK12140.1 - 0.073 13.1 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 KKK12140.1 - 0.1 12.8 0.0 0.32 11.2 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_33 PF13671.6 KKK12140.1 - 0.12 12.5 0.0 0.45 10.7 0.0 2.0 2 0 0 2 2 1 0 AAA domain Peptidase_S24 PF00717.23 KKK12141.1 - 1.6e-07 31.2 0.0 2.6e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like UQ_con PF00179.26 KKK12142.1 - 3.1e-42 143.5 0.0 3.5e-42 143.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KKK12142.1 - 8.5e-07 28.7 0.0 1e-06 28.5 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 KKK12142.1 - 0.018 14.9 0.0 0.028 14.3 0.0 1.3 1 0 0 1 1 1 0 UEV domain RWD PF05773.22 KKK12142.1 - 0.048 13.9 0.1 0.076 13.3 0.1 1.5 1 1 0 1 1 1 0 RWD domain Prok-E2_A PF14457.6 KKK12142.1 - 0.11 12.1 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family A AA_permease_2 PF13520.6 KKK12143.1 - 1.4e-45 155.9 55.7 2.4e-45 155.1 55.7 1.4 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KKK12143.1 - 1e-11 44.1 47.4 2.1e-11 43.1 47.4 1.6 1 1 0 1 1 1 1 Amino acid permease Questin_oxidase PF14027.6 KKK12144.1 - 7.4e-93 311.8 4.4 8.7e-93 311.6 4.4 1.0 1 0 0 1 1 1 1 Questin oxidase-like Fungal_trans PF04082.18 KKK12145.1 - 1.2e-05 24.5 0.2 3.1e-05 23.1 0.2 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK12145.1 - 0.075 13.2 4.1 0.12 12.5 4.1 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain ERCC4 PF02732.15 KKK12146.1 - 9.6e-28 97.4 0.0 1.5e-27 96.8 0.0 1.3 1 0 0 1 1 1 1 ERCC4 domain Epimerase PF01370.21 KKK12146.1 - 4.1e-21 75.5 0.0 6.5e-21 74.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KKK12146.1 - 1.8e-12 47.3 0.0 3.6e-12 46.3 0.0 1.5 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KKK12146.1 - 5e-10 38.9 0.0 7.3e-10 38.3 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 KKK12146.1 - 1.4e-05 24.4 0.0 2.4e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 KKK12146.1 - 2.5e-05 23.6 0.0 0.24 10.6 0.0 2.8 2 1 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.6 KKK12146.1 - 0.0046 16.9 0.0 0.0076 16.2 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Ldh_1_N PF00056.23 KKK12146.1 - 0.0092 16.1 0.0 0.016 15.3 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain KR PF08659.10 KKK12146.1 - 0.014 15.3 0.0 0.68 9.8 0.0 2.5 1 1 1 2 2 2 0 KR domain Polysacc_synt_2 PF02719.15 KKK12146.1 - 0.12 11.4 0.0 0.41 9.7 0.0 1.8 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein zf-GRF PF06839.12 KKK12148.1 - 5.3e-08 32.8 5.2 1.1e-07 31.8 5.2 1.5 1 0 0 1 1 1 1 GRF zinc finger DUF5583 PF17821.1 KKK12148.1 - 0.00056 19.9 0.6 0.00056 19.9 0.6 1.6 2 0 0 2 2 2 1 Family of unknown function (DUF5583) SecD-TM1 PF13721.6 KKK12148.1 - 0.086 13.3 0.1 0.15 12.6 0.1 1.2 1 0 0 1 1 1 0 SecD export protein N-terminal TM region DUF3818 PF12825.7 KKK12149.1 - 2e-131 438.1 3.5 3.5e-131 437.3 3.5 1.4 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.7 KKK12149.1 - 1.8e-39 134.7 0.4 3.6e-39 133.7 0.4 1.5 1 0 0 1 1 1 1 PX-associated PX PF00787.24 KKK12149.1 - 1.1e-13 51.1 0.5 4.8e-13 49.1 0.0 2.3 2 1 0 2 2 2 1 PX domain DUF2373 PF10180.9 KKK12149.1 - 0.14 12.1 1.0 0.36 10.7 1.0 1.6 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2373) zf-C2H2 PF00096.26 KKK12151.1 - 5.9e-06 26.5 11.9 0.0029 18.0 1.8 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KKK12151.1 - 0.00027 21.2 3.8 0.00027 21.2 3.8 3.1 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KKK12151.1 - 0.0004 21.0 11.3 0.071 14.0 2.9 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger TylF PF05711.11 KKK12151.1 - 0.26 10.6 0.0 0.39 9.9 0.0 1.2 1 0 0 1 1 1 0 Macrocin-O-methyltransferase (TylF) zf-H2C2_5 PF13909.6 KKK12151.1 - 1.1 9.1 5.6 2.4 8.0 0.4 2.8 2 0 0 2 2 2 0 C2H2-type zinc-finger domain ATP-synt_DE_N PF02823.16 KKK12154.1 - 4.3e-15 55.4 0.0 7.4e-15 54.6 0.0 1.3 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain Glyco_transf_90 PF05686.12 KKK12155.1 - 6.6e-12 45.0 0.4 9.7e-10 37.9 0.2 2.2 2 0 0 2 2 2 2 Glycosyl transferase family 90 zf-C2H2 PF00096.26 KKK12156.1 - 0.00019 21.7 7.5 0.0038 17.6 0.1 3.2 3 0 0 3 3 3 2 Zinc finger, C2H2 type FOXP-CC PF16159.5 KKK12156.1 - 0.002 18.7 1.1 0.21 12.3 0.1 2.7 2 0 0 2 2 2 1 FOXP coiled-coil domain zf-C2H2_4 PF13894.6 KKK12156.1 - 0.025 15.4 15.3 0.077 13.9 0.1 4.6 5 0 0 5 5 5 0 C2H2-type zinc finger CxC6 PF18721.1 KKK12156.1 - 0.46 10.8 4.7 0.36 11.1 2.2 2.1 1 1 1 2 2 2 0 CxC6 like cysteine cluster associated with KDZ transposases Cytochrom_B561 PF03188.16 KKK12157.1 - 2.3e-05 24.5 7.5 0.00026 21.1 8.8 1.9 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 DUF998 PF06197.13 KKK12157.1 - 0.006 16.2 11.7 0.14 11.8 7.8 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF998) DUF4079 PF13301.6 KKK12157.1 - 8.4 6.5 12.5 11 6.2 2.6 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF4079) DUF3759 PF12585.8 KKK12157.1 - 10 6.3 10.2 11 6.1 0.0 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF3759) Ribosomal_L29e PF01779.17 KKK12158.1 - 6e-10 39.3 0.4 1.3e-09 38.2 0.4 1.6 1 0 0 1 1 1 1 Ribosomal L29e protein family PQ-loop PF04193.14 KKK12159.1 - 1.2e-38 130.7 8.5 6.9e-20 70.6 1.4 2.5 2 0 0 2 2 2 2 PQ loop repeat DUF2374 PF09574.10 KKK12159.1 - 0.7 9.8 4.8 2.5 8.0 1.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (Duf2374) Fungal_trans PF04082.18 KKK12160.1 - 1.6e-11 43.8 2.6 2.6e-11 43.0 0.3 2.3 1 1 1 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK12160.1 - 3.3e-08 33.5 11.8 5.9e-08 32.7 11.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CRM1_repeat_3 PF18787.1 KKK12160.1 - 0.19 11.9 0.0 0.35 11.0 0.0 1.4 1 0 0 1 1 1 0 CRM1 / Exportin repeat 3 DBD_Tnp_Mut PF03108.15 KKK12161.1 - 7.1e-10 38.7 0.4 1.3e-09 37.9 0.4 1.4 1 0 0 1 1 1 1 MuDR family transposase THOC7 PF05615.13 KKK12162.1 - 3.2e-45 153.6 2.6 3.2e-45 153.6 2.6 2.1 1 1 1 2 2 2 1 Tho complex subunit 7 Mod_r PF07200.13 KKK12162.1 - 0.0056 16.8 11.3 0.0097 16.0 11.3 1.4 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein FapA PF03961.13 KKK12162.1 - 0.27 9.8 2.7 0.39 9.3 2.7 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A DivIC PF04977.15 KKK12162.1 - 5 7.0 9.4 0.94 9.3 3.5 2.7 1 1 1 2 2 2 0 Septum formation initiator FUSC PF04632.12 KKK12162.1 - 7.1 5.0 8.4 9.4 4.6 8.4 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Ribosomal_L44 PF00935.19 KKK12163.1 - 7.5e-36 122.5 12.4 1.4e-35 121.6 12.4 1.5 1 0 0 1 1 1 1 Ribosomal protein L44 Elongin_A PF06881.11 KKK12164.1 - 1.9e-28 99.0 0.6 3.7e-28 98.1 0.1 1.7 2 0 0 2 2 2 1 RNA polymerase II transcription factor SIII (Elongin) subunit A Band_7 PF01145.25 KKK12165.1 - 2.5e-14 53.7 0.1 2.5e-14 53.7 0.1 2.3 2 0 0 2 2 2 1 SPFH domain / Band 7 family Atg14 PF10186.9 KKK12165.1 - 1.1 8.3 10.0 1.7 7.7 10.0 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 TBCA PF02970.16 KKK12166.1 - 4.8e-23 81.3 7.8 5.9e-23 81.0 7.8 1.2 1 0 0 1 1 1 1 Tubulin binding cofactor A T3SSipB PF16535.5 KKK12166.1 - 0.0028 18.1 1.6 0.0028 18.1 1.6 2.0 1 1 1 2 2 2 1 Type III cell invasion protein SipB Sugar_tr PF00083.24 KKK12167.1 - 9.9e-82 275.2 18.6 1.2e-81 274.9 18.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKK12167.1 - 2e-29 102.6 17.0 3.2e-28 98.7 14.8 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KKK12167.1 - 0.0058 15.1 1.0 0.0058 15.1 1.0 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) EXS PF03124.14 KKK12167.1 - 3.8 6.7 6.8 8.7 5.6 0.2 2.7 3 0 0 3 3 3 0 EXS family Ilm1 PF10311.9 KKK12168.1 - 1.2e-63 213.6 1.3 1.4e-63 213.4 1.3 1.0 1 0 0 1 1 1 1 Increased loss of mitochondrial DNA protein 1 Prenyltrans PF00432.21 KKK12169.1 - 9e-33 111.7 9.9 2.1e-10 40.1 0.1 6.5 6 1 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_C PF13243.6 KKK12169.1 - 0.02 14.0 0.0 0.61 9.1 0.0 2.9 2 1 0 2 2 2 0 Squalene-hopene cyclase C-terminal domain Eisosome1 PF12757.7 KKK12170.1 - 1.7e-29 102.6 9.8 1.7e-29 102.6 9.8 3.3 5 0 0 5 5 5 1 Eisosome protein 1 Glyco_hydro_35 PF01301.19 KKK12171.1 - 3.6e-83 279.8 4.9 5.4e-83 279.2 4.9 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.6 KKK12171.1 - 9.6e-59 196.9 0.4 2.9e-32 111.6 0.0 2.8 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain BetaGal_dom2 PF10435.9 KKK12171.1 - 4e-54 183.2 2.9 4e-54 183.2 2.9 1.9 2 0 0 2 2 2 1 Beta-galactosidase, domain 2 BetaGal_dom3 PF13363.6 KKK12171.1 - 2.5e-24 84.6 0.2 1.3e-23 82.3 0.1 2.2 2 0 0 2 2 2 1 Beta-galactosidase, domain 3 Glyco_hydro_42 PF02449.15 KKK12171.1 - 1.3e-05 24.7 0.2 0.0002 20.8 0.4 2.3 1 1 1 2 2 2 1 Beta-galactosidase Cellulase PF00150.18 KKK12171.1 - 3.7e-05 23.3 1.7 0.011 15.1 0.6 2.7 2 1 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) CFEM PF05730.11 KKK12172.1 - 4e-14 52.5 15.3 4e-14 52.5 15.3 2.3 2 1 0 2 2 2 1 CFEM domain Tmemb_cc2 PF10267.9 KKK12172.1 - 0.14 11.3 5.0 0.15 11.2 5.0 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein SOG2 PF10428.9 KKK12172.1 - 0.98 8.5 13.8 1.2 8.3 13.8 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Macoilin PF09726.9 KKK12172.1 - 1.6 7.2 8.6 1.8 7.0 8.6 1.1 1 0 0 1 1 1 0 Macoilin family Mog1 PF04603.12 KKK12172.1 - 1.8 8.9 5.1 3.4 8.0 5.1 1.5 1 1 0 1 1 1 0 Ran-interacting Mog1 protein GREB1 PF15782.5 KKK12172.1 - 2.2 5.3 6.1 2.3 5.3 6.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF515 PF04415.12 KKK12172.1 - 3 6.2 15.8 3.4 5.9 15.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF515) TIL PF01826.17 KKK12172.1 - 5.1 7.4 13.3 1.4 9.2 9.5 2.0 2 0 0 2 2 2 0 Trypsin Inhibitor like cysteine rich domain MFS_1 PF07690.16 KKK12173.1 - 2.3e-34 118.9 18.4 2.3e-34 118.9 18.4 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KKK12173.1 - 2.4e-10 39.9 6.2 2.4e-10 39.9 6.2 3.0 2 1 1 3 3 3 1 Sugar (and other) transporter Phage_holin_3_1 PF05106.12 KKK12173.1 - 1.1 9.7 7.5 1.8 9.1 0.3 3.1 3 0 0 3 3 3 0 Phage holin family (Lysis protein S) Alpha-amylase PF00128.24 KKK12181.1 - 1.4e-17 64.3 2.2 2.4e-17 63.5 0.8 2.1 2 1 0 2 2 2 1 Alpha amylase, catalytic domain Glyco_transf_5 PF08323.11 KKK12181.1 - 2.5e-14 53.5 0.1 4.3e-14 52.8 0.1 1.3 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 KKK12181.1 - 6.4e-05 22.5 0.0 0.00014 21.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KKK12181.1 - 0.0016 18.5 0.0 0.0045 17.0 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase Family 4 TPT PF03151.16 KKK12182.1 - 2.5e-24 86.1 27.8 3.3e-24 85.7 27.8 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 KKK12182.1 - 0.84 8.8 28.5 1.7 7.8 28.5 1.4 1 1 0 1 1 1 0 UAA transporter family DUF4131 PF13567.6 KKK12182.1 - 1.7 8.3 6.9 1.2e+02 2.3 0.0 4.1 3 1 0 3 3 3 0 Domain of unknown function (DUF4131) CbtB PF09489.10 KKK12182.1 - 4.9 7.3 7.7 2 8.6 0.1 3.0 3 0 0 3 3 3 0 Probable cobalt transporter subunit (CbtB) ECR1_N PF14382.6 KKK12183.1 - 1.3e-14 53.7 0.1 3e-14 52.5 0.1 1.7 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region KH_6 PF15985.5 KKK12183.1 - 3.4e-06 27.3 0.4 7e-06 26.3 0.4 1.5 1 0 0 1 1 1 1 KH domain EXOSC1 PF10447.9 KKK12183.1 - 0.19 12.4 1.7 1.6 9.3 0.1 2.7 3 0 0 3 3 3 0 Exosome component EXOSC1/CSL4 IFRD PF05004.13 KKK12184.1 - 1.3e-85 287.2 5.6 1.8e-85 286.7 5.6 1.1 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) Cnd3 PF12719.7 KKK12184.1 - 0.0002 20.7 0.1 0.00044 19.6 0.0 1.7 1 1 0 1 1 1 1 Nuclear condensing complex subunits, C-term domain HEAT_EZ PF13513.6 KKK12184.1 - 0.025 15.1 0.0 1 10.0 0.0 2.8 2 1 0 2 2 2 0 HEAT-like repeat PDDEXK_6 PF04720.12 KKK12184.1 - 0.87 9.5 7.4 0.35 10.8 0.9 2.3 2 0 0 2 2 2 0 PDDEXK-like family of unknown function DNA_pol_phi PF04931.13 KKK12184.1 - 4.1 5.4 10.4 2.2 6.3 4.7 2.3 2 1 0 2 2 2 0 DNA polymerase phi Oxysterol_BP PF01237.18 KKK12185.1 - 3e-119 398.2 0.0 6.6e-119 397.1 0.0 1.6 1 0 0 1 1 1 1 Oxysterol-binding protein PH_8 PF15409.6 KKK12185.1 - 1.3e-37 127.9 0.5 2.4e-37 127.1 0.0 1.7 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.29 KKK12185.1 - 1.1e-08 35.5 0.5 1.1e-07 32.3 0.0 2.4 2 0 0 2 2 2 1 PH domain PH_11 PF15413.6 KKK12185.1 - 0.032 14.6 3.4 5.1 7.6 0.1 3.0 2 1 0 3 3 3 0 Pleckstrin homology domain N_BRCA1_IG PF16158.5 KKK12186.1 - 1.9e-32 112.0 0.0 4.5e-32 110.8 0.0 1.7 1 0 0 1 1 1 1 Ig-like domain from next to BRCA1 gene ZZ PF00569.17 KKK12186.1 - 5e-21 74.2 51.9 3.7e-07 29.9 9.0 4.4 4 0 0 4 4 4 4 Zinc finger, ZZ type C1_2 PF03107.16 KKK12186.1 - 0.0038 17.5 43.4 0.18 12.1 9.7 4.5 4 0 0 4 4 4 4 C1 domain RRM_1 PF00076.22 KKK12187.1 - 2.3e-21 75.4 0.4 1e-12 47.7 0.1 3.0 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KKK12187.1 - 0.0021 18.1 0.1 0.0061 16.5 0.1 1.8 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 KKK12187.1 - 0.0026 17.9 0.0 0.74 10.0 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif Spt5_N PF11942.8 KKK12187.1 - 2.3 9.2 9.6 2.3 9.2 7.7 2.0 1 1 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal Btz PF09405.10 KKK12188.1 - 1.5e-33 115.8 3.1 1.5e-33 115.8 3.1 2.1 3 0 0 3 3 3 1 CASC3/Barentsz eIF4AIII binding Ino80_Iec3 PF14612.6 KKK12189.1 - 2.8e-78 263.8 0.1 4.4e-78 263.2 0.1 1.3 1 0 0 1 1 1 1 IEC3 subunit of the Ino80 complex, chromatin re-modelling Fungal_trans PF04082.18 KKK12204.1 - 7.6e-32 110.4 0.0 1.5e-31 109.5 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK12204.1 - 5.1e-08 32.9 7.9 5.1e-08 32.9 7.9 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain IMS PF00817.20 KKK12205.1 - 2.2e-41 141.4 0.0 3.9e-41 140.5 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family REV1_C PF16727.5 KKK12205.1 - 6e-22 77.9 1.6 1.2e-21 76.9 1.6 1.5 1 0 0 1 1 1 1 DNA repair protein REV1 C-terminal domain IMS_C PF11799.8 KKK12205.1 - 3e-14 53.7 0.0 8e-14 52.3 0.0 1.7 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain UBM PF14377.6 KKK12205.1 - 2e-11 42.9 8.1 2.9e-08 32.9 0.3 4.0 3 0 0 3 3 3 2 Ubiquitin binding region BRCT_2 PF16589.5 KKK12205.1 - 3.6e-08 33.7 0.0 1.1e-07 32.1 0.0 1.9 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain IMS_HHH PF11798.8 KKK12205.1 - 3.6e-06 27.0 0.1 1.9e-05 24.7 0.0 2.3 2 0 0 2 2 2 1 IMS family HHH motif LIG3_BRCT PF16759.5 KKK12205.1 - 0.0012 19.1 0.0 0.0022 18.2 0.0 1.5 1 0 0 1 1 1 1 DNA ligase 3 BRCT domain mCpol PF18182.1 KKK12205.1 - 0.0014 18.9 0.1 0.003 17.9 0.1 1.5 1 0 0 1 1 1 1 minimal CRISPR polymerase domain BRCT PF00533.26 KKK12205.1 - 0.002 18.4 0.0 0.0068 16.8 0.0 1.9 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 KKK12205.1 - 0.0069 16.3 0.0 0.015 15.2 0.0 1.6 1 0 0 1 1 1 1 twin BRCT domain Cdd1 PF11731.8 KKK12205.1 - 0.018 15.3 0.0 0.061 13.6 0.0 1.9 1 0 0 1 1 1 0 Pathogenicity locus AT_hook PF02178.19 KKK12205.1 - 2.5 8.3 6.6 10 6.3 6.6 2.1 1 0 0 1 1 1 0 AT hook motif adh_short PF00106.25 KKK12206.1 - 4.7e-54 182.8 0.1 6.1e-54 182.4 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KKK12206.1 - 2.2e-37 128.8 0.0 2.8e-37 128.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KKK12206.1 - 5e-13 49.4 0.0 7.3e-13 48.8 0.0 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KKK12206.1 - 0.00061 19.0 0.1 0.0015 17.8 0.1 1.7 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein DUF1776 PF08643.10 KKK12206.1 - 0.0071 15.8 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Sacchrp_dh_NADP PF03435.18 KKK12206.1 - 0.014 15.6 0.1 0.033 14.4 0.1 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 KKK12206.1 - 0.016 14.6 0.1 0.04 13.4 0.1 1.8 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family RPN13_C PF16550.5 KKK12206.1 - 0.15 12.3 0.1 12 6.1 0.0 2.7 2 1 1 3 3 3 0 UCH-binding domain GATA PF00320.27 KKK12207.1 - 2.6e-28 97.3 17.3 1.3e-14 53.5 6.0 2.5 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.12 KKK12207.1 - 1e-05 24.9 3.7 0.0064 16.0 0.1 2.4 2 0 0 2 2 2 2 TFIIB zinc-binding Zn-ribbon_8 PF09723.10 KKK12207.1 - 0.00019 21.5 2.7 0.1 12.7 0.3 2.6 2 0 0 2 2 2 2 Zinc ribbon domain OrfB_Zn_ribbon PF07282.11 KKK12207.1 - 0.0011 18.8 4.5 0.075 13.0 0.5 2.6 2 0 0 2 2 2 2 Putative transposase DNA-binding domain Auto_anti-p27 PF06677.12 KKK12207.1 - 0.0014 18.7 5.4 0.049 13.8 0.4 2.4 2 0 0 2 2 2 2 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) eIF-5_eIF-2B PF01873.17 KKK12207.1 - 0.019 14.8 3.7 2.4 8.0 0.4 2.4 2 0 0 2 2 2 0 Domain found in IF2B/IF5 DZR PF12773.7 KKK12207.1 - 0.036 14.1 10.2 28 4.8 10.4 3.0 1 1 0 1 1 1 0 Double zinc ribbon ArfGap PF01412.18 KKK12207.1 - 0.11 12.5 3.6 0.64 10.1 0.2 2.3 2 0 0 2 2 2 0 Putative GTPase activating protein for Arf Neisseria_TspB PF05616.13 KKK12207.1 - 1.6 7.2 6.2 0.46 8.9 0.5 2.1 2 0 0 2 2 2 0 Neisseria meningitidis TspB protein RPA_interact_C PF14768.6 KKK12207.1 - 2.6 8.7 4.2 17 6.0 0.0 3.4 3 1 1 4 4 4 0 Replication protein A interacting C-terminal Rubredoxin_2 PF18073.1 KKK12207.1 - 4 7.2 10.6 18 5.2 0.2 4.4 4 0 0 4 4 4 0 Rubredoxin metal binding domain Amidohydro_1 PF01979.20 KKK12208.1 - 2.8e-64 217.6 0.0 3.3e-64 217.4 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KKK12208.1 - 1.2e-14 54.6 0.0 6.4e-12 45.7 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family A_deaminase PF00962.22 KKK12208.1 - 0.0022 17.4 0.0 0.0041 16.5 0.0 1.5 1 0 0 1 1 1 1 Adenosine/AMP deaminase RHH_1 PF01402.21 KKK12208.1 - 0.12 12.3 0.2 20 5.3 0.0 2.6 2 0 0 2 2 2 0 Ribbon-helix-helix protein, copG family MFS_1 PF07690.16 KKK12210.1 - 1.1e-32 113.4 31.7 4.5e-32 111.4 31.7 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KKK12210.1 - 8e-10 37.8 8.2 9.3e-10 37.5 8.2 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Ycf70 PF17382.2 KKK12210.1 - 0.081 13.3 0.1 1.1 9.7 0.0 2.7 3 0 0 3 3 3 0 Uncharacterized Ycf70-like Oxidored_q2 PF00420.24 KKK12210.1 - 0.1 12.3 1.4 0.57 9.8 0.0 2.6 3 0 0 3 3 3 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L UNC-93 PF05978.16 KKK12210.1 - 0.16 11.7 8.7 0.2 11.3 7.4 2.0 1 1 0 1 1 1 0 Ion channel regulatory protein UNC-93 Hexokinase_2 PF03727.16 KKK12211.1 - 1.9e-80 269.8 0.0 2.5e-80 269.4 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 KKK12211.1 - 1.3e-72 243.9 0.0 1.8e-72 243.4 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Adaptin_N PF01602.20 KKK12230.1 - 6.9e-35 120.6 0.2 7.8e-35 120.4 0.2 1.0 1 0 0 1 1 1 1 Adaptin N terminal region DUF1160 PF06648.11 KKK12230.1 - 0.037 14.0 0.6 0.063 13.3 0.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1160) Peptidase_S48 PF03574.15 KKK12230.1 - 0.089 13.0 0.1 0.21 11.8 0.0 1.6 1 1 1 2 2 2 0 Peptidase family S48 DUF1804 PF08822.11 KKK12269.1 - 0.015 15.3 0.1 0.024 14.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1804) DUF4473 PF14747.6 KKK12269.1 - 0.038 14.5 0.0 0.071 13.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4473) Tfb5 PF06331.12 KKK12269.1 - 0.1 12.6 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 Transcription factor TFIIH complex subunit Tfb5 PAPS_reduct PF01507.19 KKK12270.1 - 5.5e-27 94.9 0.0 3.9e-25 88.9 0.0 2.0 1 1 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family RRM_1 PF00076.22 KKK12271.1 - 9.1e-23 79.9 0.1 1.2e-10 41.0 0.1 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NAD_binding_11 PF14833.6 KKK12272.1 - 5e-30 104.2 0.0 8.6e-30 103.5 0.0 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase NAD_binding_2 PF03446.15 KKK12272.1 - 3.8e-27 95.4 1.1 1.6e-26 93.3 0.0 2.1 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase UDPG_MGDP_dh PF00984.19 KKK12272.1 - 0.034 14.3 0.1 0.17 12.1 0.1 2.1 2 1 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, central domain TGS PF02824.21 KKK12272.1 - 0.12 12.4 0.1 0.46 10.6 0.0 1.9 2 0 0 2 2 2 0 TGS domain DUF202 PF02656.15 KKK12273.1 - 3.5e-22 78.6 1.4 3.5e-22 78.6 1.4 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF202) PTPA PF03095.15 KKK12274.1 - 1.7e-110 369.2 0.0 2.1e-110 368.9 0.0 1.1 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Ribosomal_L7Ae PF01248.26 KKK12279.1 - 2.2e-24 85.0 0.6 5e-24 83.8 0.6 1.6 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Ank_2 PF12796.7 KKK12279.1 - 1.7e-20 73.4 0.2 4.6e-12 46.3 0.1 2.9 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KKK12279.1 - 1.7e-16 60.4 0.0 0.00043 20.8 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KKK12279.1 - 4.5e-16 58.7 0.3 5.5e-07 29.7 0.1 4.4 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 KKK12279.1 - 1.2e-13 50.9 0.1 0.0012 19.2 0.0 4.7 4 0 0 4 4 4 4 Ankyrin repeat Ank_3 PF13606.6 KKK12279.1 - 3.4e-10 39.3 0.1 0.057 14.0 0.0 4.5 5 0 0 5 5 5 3 Ankyrin repeat MR_MLE_C PF13378.6 KKK12280.1 - 1.1e-56 191.9 0.0 1.5e-56 191.4 0.0 1.1 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 KKK12280.1 - 1.2e-17 64.2 0.0 2.6e-17 63.1 0.0 1.5 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Vac_ImportDeg PF09783.9 KKK12281.1 - 1.8e-41 141.6 0.2 5.3e-41 140.1 0.2 1.7 2 0 0 2 2 2 1 Vacuolar import and degradation protein PXA PF02194.15 KKK12282.1 - 1.2e-47 162.2 0.1 1.8e-47 161.7 0.1 1.2 1 0 0 1 1 1 1 PXA domain PUL PF08324.11 KKK12282.1 - 0.11 11.7 0.3 0.81 8.9 0.1 2.3 3 0 0 3 3 3 0 PUL domain IU_nuc_hydro PF01156.19 KKK12283.1 - 3.8e-82 276.3 0.0 4.5e-82 276.0 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Ribosomal_S7e PF01251.18 KKK12287.1 - 3.8e-83 277.8 0.2 4.8e-83 277.5 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S7e Dynactin_p62 PF05502.13 KKK12288.1 - 4.3e-143 477.5 5.7 2.3e-92 310.3 0.1 2.7 2 1 1 3 3 3 2 Dynactin p62 family Cwf_Cwc_15 PF04889.12 KKK12288.1 - 0.0033 17.2 11.8 0.0033 17.2 11.8 1.7 2 0 0 2 2 2 1 Cwf15/Cwc15 cell cycle control protein Sporozoite_P67 PF05642.11 KKK12288.1 - 0.24 9.5 6.8 0.39 8.7 6.8 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Sigma70_ner PF04546.13 KKK12288.1 - 0.97 9.3 9.9 2.2 8.1 9.9 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region SDA1 PF05285.12 KKK12288.1 - 1.3 8.4 12.9 2.5 7.4 12.9 1.4 1 0 0 1 1 1 0 SDA1 DUF1115 PF06544.12 KKK12288.1 - 1.4 9.0 6.6 1.1 9.4 4.6 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1115) Nop14 PF04147.12 KKK12288.1 - 2 6.5 17.3 0.039 12.2 10.6 1.4 2 0 0 2 2 2 0 Nop14-like family YL1 PF05764.13 KKK12288.1 - 2.7 8.1 10.7 5.8 7.0 10.7 1.5 1 0 0 1 1 1 0 YL1 nuclear protein DNA_pol_phi PF04931.13 KKK12288.1 - 2.9 5.9 25.0 4.3 5.3 25.0 1.2 1 0 0 1 1 1 0 DNA polymerase phi FdhE PF04216.12 KKK12288.1 - 4 7.3 6.7 7.9 6.3 6.4 1.6 1 1 0 1 1 1 0 Protein involved in formate dehydrogenase formation FYDLN_acid PF09538.10 KKK12288.1 - 5.9 7.6 23.1 5.3 7.8 16.4 2.8 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) CDC45 PF02724.14 KKK12288.1 - 8.6 4.5 14.0 14 3.9 14.0 1.2 1 0 0 1 1 1 0 CDC45-like protein Cation_ATPase_C PF00689.21 KKK12289.1 - 3e-47 160.7 10.0 3e-47 160.7 10.0 2.0 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 KKK12289.1 - 7.8e-38 129.8 0.2 7.8e-38 129.8 0.2 2.4 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase PF13246.6 KKK12289.1 - 1.5e-20 73.1 0.0 2.7e-20 72.2 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KKK12289.1 - 6.3e-17 62.6 0.0 1.7e-16 61.1 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KKK12289.1 - 9.2e-08 31.7 0.8 1.5e-06 27.8 0.1 2.6 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KKK12289.1 - 0.00019 21.2 0.1 0.0021 17.9 0.1 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase K_oxygenase PF13434.6 KKK12290.1 - 1.9e-16 60.2 0.0 6.1e-12 45.3 0.0 2.5 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 KKK12290.1 - 3.7e-08 33.0 0.0 0.016 14.5 0.0 3.0 2 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KKK12290.1 - 3e-06 26.7 0.0 0.0079 15.5 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KKK12290.1 - 0.00013 21.3 0.0 0.003 16.9 0.0 2.4 3 0 0 3 3 3 1 FAD binding domain NAD_binding_9 PF13454.6 KKK12290.1 - 0.00071 19.6 0.7 0.51 10.3 0.1 3.4 3 2 0 3 3 3 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KKK12290.1 - 0.0014 18.8 0.0 0.076 13.3 0.0 2.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KKK12290.1 - 0.002 17.8 0.0 5.4 6.5 0.0 3.3 3 0 0 3 3 3 2 FAD dependent oxidoreductase Pinin_SDK_N PF04697.13 KKK12290.1 - 0.02 15.6 2.4 0.02 15.6 2.4 1.6 2 0 0 2 2 1 0 pinin/SDK conserved region GIDA PF01134.22 KKK12290.1 - 0.037 13.1 0.3 0.48 9.4 0.0 2.5 2 1 0 3 3 3 0 Glucose inhibited division protein A Lycopene_cycl PF05834.12 KKK12290.1 - 0.058 12.4 0.2 0.27 10.2 0.0 2.1 3 0 0 3 3 3 0 Lycopene cyclase protein Pyr_redox PF00070.27 KKK12290.1 - 0.065 13.8 0.0 11 6.7 0.0 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 KKK12290.1 - 0.069 13.2 0.0 1.4 9.0 0.0 2.2 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase SR-25 PF10500.9 KKK12290.1 - 0.15 11.6 8.9 0.25 10.9 8.9 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein HI0933_like PF03486.14 KKK12290.1 - 0.2 10.3 0.0 0.85 8.2 0.0 1.9 3 0 0 3 3 3 0 HI0933-like protein Methyltransf_11 PF08241.12 KKK12291.1 - 7.4e-09 36.1 0.0 1.5e-08 35.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KKK12291.1 - 4.8e-08 33.0 0.0 7.7e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KKK12291.1 - 9.4e-07 29.5 0.0 2e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKK12291.1 - 2.2e-05 25.1 0.0 6.6e-05 23.5 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KKK12291.1 - 0.0049 16.7 0.0 0.023 14.5 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain P16-Arc PF04699.14 KKK12292.1 - 1.4e-46 158.7 0.0 1.6e-46 158.5 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) HMG_CoA_synt_C PF08540.10 KKK12293.1 - 1.4e-106 356.2 0.8 2.1e-106 355.6 0.8 1.3 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.17 KKK12293.1 - 3.2e-96 320.2 0.1 4.9e-96 319.6 0.1 1.3 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal Oxysterol_BP PF01237.18 KKK12321.1 - 3.3e-62 210.5 2.9 2e-54 184.9 0.0 2.0 1 1 1 2 2 2 2 Oxysterol-binding protein RSN1_TM PF13967.6 KKK12323.1 - 7.1e-40 136.3 2.2 8.9e-40 136.0 2.2 1.1 1 0 0 1 1 1 1 Late exocytosis, associated with Golgi transport RSN1_7TM PF02714.15 KKK12324.1 - 7.7e-84 281.2 24.7 9.7e-84 280.9 24.7 1.1 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 KKK12324.1 - 1.3e-32 113.4 0.0 2.1e-32 112.8 0.0 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter F_bP_aldolase PF01116.20 KKK12325.1 - 6.9e-92 307.9 0.0 7.7e-92 307.7 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II Glyco_transf_4 PF13439.6 KKK12326.1 - 0.11 12.4 0.0 8.5 6.3 0.0 2.5 2 0 0 2 2 2 0 Glycosyltransferase Family 4 DUF4078 PF13300.6 KKK12327.1 - 1.9e-25 89.0 16.8 1.9e-25 89.0 16.8 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4078) CENP-H PF05837.12 KKK12328.1 - 2.9e-32 111.4 5.5 2.9e-32 111.4 5.5 2.1 2 0 0 2 2 2 2 Centromere protein H (CENP-H) DivIC PF04977.15 KKK12328.1 - 0.079 12.7 14.2 0.74 9.6 0.6 3.3 3 0 0 3 3 3 0 Septum formation initiator HMG_box PF00505.19 KKK12329.1 - 4.5e-26 91.1 1.1 6.5e-26 90.5 1.1 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KKK12329.1 - 2.3e-19 69.8 1.5 3.5e-19 69.1 1.5 1.3 1 0 0 1 1 1 1 HMG-box domain Ccdc124 PF06244.12 KKK12329.1 - 0.00067 20.2 1.3 0.0018 18.9 0.0 2.0 1 1 1 2 2 2 1 Coiled-coil domain-containing protein 124 /Oxs1 CHDNT PF08073.12 KKK12329.1 - 0.0082 16.1 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 CHDNT (NUC034) domain Homoserine_dh PF00742.19 KKK12330.1 - 6.3e-52 176.0 0.0 8.2e-52 175.6 0.0 1.1 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.16 KKK12330.1 - 3.8e-14 53.3 0.0 7.8e-14 52.3 0.0 1.6 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain DUF3445 PF11927.8 KKK12331.1 - 5.8e-22 78.4 0.0 1.1e-21 77.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) DUF3530 PF12048.8 KKK12331.1 - 0.053 12.9 0.1 0.07 12.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) PNP_UDP_1 PF01048.20 KKK12332.1 - 2.5e-07 30.2 1.0 9.6e-07 28.3 1.0 1.8 1 1 0 1 1 1 1 Phosphorylase superfamily Ribosomal_S19 PF00203.21 KKK12333.1 - 5.8e-22 77.4 0.0 7.3e-22 77.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S19 AMP-binding PF00501.28 KKK12334.1 - 9.3e-47 159.6 0.0 1.2e-46 159.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Beta-lactamase PF00144.24 KKK12335.1 - 4.1e-29 101.9 1.1 4e-28 98.6 1.1 2.0 1 1 0 1 1 1 1 Beta-lactamase FAD_binding_3 PF01494.19 KKK12336.1 - 1.1e-09 38.0 0.1 3.5e-06 26.5 0.0 3.2 3 0 0 3 3 3 2 FAD binding domain DAO PF01266.24 KKK12336.1 - 0.00012 21.7 0.0 0.00021 21.0 0.0 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KKK12336.1 - 0.00059 19.9 0.0 0.032 14.2 0.0 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KKK12336.1 - 0.0027 17.9 0.8 0.0067 16.6 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KKK12336.1 - 0.0038 16.5 0.0 0.02 14.1 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Questin_oxidase PF14027.6 KKK12337.1 - 7.6e-82 275.6 0.1 9.9e-82 275.2 0.1 1.1 1 0 0 1 1 1 1 Questin oxidase-like NAD_binding_10 PF13460.6 KKK12337.1 - 4.4e-15 56.0 0.0 9.4e-15 55.0 0.0 1.6 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KKK12337.1 - 0.0011 18.6 0.1 0.0024 17.5 0.0 1.6 2 0 0 2 2 2 1 NmrA-like family 3Beta_HSD PF01073.19 KKK12337.1 - 0.0082 15.2 0.7 0.014 14.4 0.1 1.6 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KKK12337.1 - 0.12 11.8 0.0 0.35 10.3 0.0 1.8 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 KKK12337.1 - 0.16 12.4 0.0 2.7 8.4 0.0 2.7 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain GST_C PF00043.25 KKK12338.1 - 5.5e-09 36.1 0.0 1.1e-08 35.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KKK12338.1 - 2.7e-07 30.5 0.1 4.5e-07 29.8 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KKK12338.1 - 2.7e-07 30.7 0.0 4.5e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KKK12338.1 - 3.2e-07 30.6 0.0 6.1e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain TRF PF08558.10 KKK12339.1 - 7.6e-93 310.5 2.5 1.1e-92 309.9 2.5 1.3 1 0 0 1 1 1 1 Telomere repeat binding factor (TRF) Myb_DNA-binding PF00249.31 KKK12339.1 - 0.00063 19.9 0.0 0.0012 19.0 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain eIF-3_zeta PF05091.12 KKK12339.1 - 0.39 9.6 15.3 0.8 8.6 15.3 1.5 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) EOS1 PF12326.8 KKK12339.1 - 0.89 9.5 5.4 2.5 8.0 5.4 1.7 1 0 0 1 1 1 0 N-glycosylation protein SLC12 PF03522.15 KKK12339.1 - 5.2 6.0 13.3 12 4.8 13.3 1.7 1 0 0 1 1 1 0 Solute carrier family 12 DUF2981 PF11200.8 KKK12339.1 - 9.6 5.8 9.4 23 4.6 9.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) TFIID_30kDa PF03540.13 KKK12340.1 - 9.8e-23 79.9 0.1 1.5e-22 79.3 0.1 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit FoP_duplication PF13865.6 KKK12340.1 - 0.34 11.5 2.2 0.77 10.3 2.2 1.7 1 1 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Dicty_CAR PF05462.11 KKK12350.1 - 2.6e-14 53.1 18.3 8.6e-14 51.4 11.2 2.1 2 0 0 2 2 2 2 Slime mold cyclic AMP receptor 7tm_2 PF00002.24 KKK12350.1 - 7.7e-12 45.0 6.8 1.2e-11 44.4 6.8 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) 7tm_1 PF00001.21 KKK12350.1 - 4.9e-09 35.9 0.8 6.9e-09 35.4 0.8 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Git3 PF11710.8 KKK12350.1 - 1.4e-06 28.2 13.6 1.4e-06 28.2 13.6 1.5 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 7TM_GPCR_Srsx PF10320.9 KKK12350.1 - 0.001 18.5 3.5 0.001 18.5 3.5 1.8 3 0 0 3 3 3 1 Serpentine type 7TM GPCR chemoreceptor Srsx Frizzled PF01534.17 KKK12350.1 - 0.017 14.2 13.3 0.2 10.7 13.3 2.2 1 1 0 1 1 1 0 Frizzled/Smoothened family membrane region TMEMspv1-c74-12 PF11044.8 KKK12350.1 - 0.079 13.0 0.1 0.16 12.0 0.1 1.4 1 0 0 1 1 1 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein TAL_FSA PF00923.19 KKK12351.1 - 5.5e-19 68.6 0.0 6e-19 68.5 0.0 1.1 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase PQ-loop PF04193.14 KKK12352.1 - 2e-39 133.2 17.8 6.9e-21 73.8 1.3 3.1 3 0 0 3 3 3 2 PQ loop repeat DUF2157 PF09925.9 KKK12352.1 - 0.02 14.7 1.1 2.8 7.7 1.7 2.6 2 1 0 2 2 2 0 Predicted membrane protein (DUF2157) DUF1294 PF06961.13 KKK12352.1 - 0.11 12.8 0.8 0.65 10.3 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1294) SGS PF05002.15 KKK12353.1 - 2.7e-27 94.7 4.2 1.4e-26 92.4 4.2 2.2 1 1 0 1 1 1 1 SGS domain CS PF04969.16 KKK12353.1 - 0.00037 21.4 0.0 0.00068 20.6 0.0 1.4 1 0 0 1 1 1 1 CS domain TPR_2 PF07719.17 KKK12353.1 - 0.0022 18.0 0.3 2.1 8.7 0.2 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 KKK12353.1 - 0.0022 17.7 0.0 2.2 8.3 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 KKK12353.1 - 0.0094 16.6 5.6 1.6 9.4 0.5 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat Dicty_REP PF05086.12 KKK12353.1 - 0.18 9.7 4.4 0.24 9.4 4.4 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Pkinase PF00069.25 KKK12354.1 - 4.7e-75 252.4 0.0 6.2e-75 252.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK12354.1 - 2e-36 125.6 0.0 3e-36 125.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase SIR2 PF02146.17 KKK12354.1 - 1e-30 107.0 0.0 1.6e-30 106.4 0.0 1.3 1 0 0 1 1 1 1 Sir2 family Haspin_kinase PF12330.8 KKK12354.1 - 0.00099 18.1 0.0 0.005 15.8 0.0 1.9 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KKK12354.1 - 0.012 15.0 0.2 0.012 15.0 0.2 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KKK12354.1 - 0.012 14.9 0.0 0.029 13.7 0.0 1.6 1 0 0 1 1 1 0 Kinase-like DUF3716 PF12511.8 KKK12355.1 - 4.7e-15 55.4 6.6 7.1e-15 54.8 6.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) Myc_N PF01056.18 KKK12355.1 - 0.0029 17.6 4.8 0.055 13.4 0.3 2.1 2 0 0 2 2 2 2 Myc amino-terminal region HCMV_UL139 PF12507.8 KKK12355.1 - 0.026 14.9 0.0 2.3 8.6 0.0 2.3 1 1 1 2 2 2 0 Human Cytomegalovirus UL139 protein MPP6 PF10175.9 KKK12355.1 - 0.032 14.7 5.6 1.6 9.2 0.1 2.2 2 0 0 2 2 2 0 M-phase phosphoprotein 6 Folliculin PF11704.8 KKK12355.1 - 0.14 12.1 0.2 0.25 11.2 0.2 1.5 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport Mntp PF02659.15 KKK12355.1 - 0.19 11.5 1.2 0.2 11.4 0.0 1.5 2 0 0 2 2 2 0 Putative manganese efflux pump FAM176 PF14851.6 KKK12355.1 - 0.56 9.9 10.6 0.25 11.0 0.9 2.2 2 0 0 2 2 2 0 FAM176 family RPN2_C PF18004.1 KKK12355.1 - 0.57 10.1 7.1 3.9 7.4 0.5 2.1 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain Radial_spoke PF04712.12 KKK12355.1 - 0.88 8.4 14.7 0.12 11.3 0.4 2.0 2 0 0 2 2 2 0 Radial spokehead-like protein DUF3682 PF12446.8 KKK12355.1 - 1.2 9.6 13.7 5.2 7.6 1.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3682) PI3K_1B_p101 PF10486.9 KKK12355.1 - 3.2 5.4 4.8 3.3 5.4 3.7 1.4 1 1 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit SQHop_cyclase_C PF13243.6 KKK12356.1 - 1.2e-49 169.2 0.0 1.2e-46 159.3 0.9 2.2 2 0 0 2 2 2 2 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 KKK12356.1 - 7.8e-46 156.5 1.6 6.5e-39 133.8 0.1 3.5 3 1 1 4 4 4 2 Squalene-hopene cyclase N-terminal domain Prenyltrans PF00432.21 KKK12356.1 - 6.9e-34 115.3 8.5 4.9e-11 42.2 0.3 5.1 5 0 0 5 5 5 3 Prenyltransferase and squalene oxidase repeat TED_complement PF07678.14 KKK12356.1 - 9.8e-06 24.8 0.3 0.021 13.9 0.5 3.6 1 1 2 3 3 3 2 A-macroglobulin TED domain Pec_lyase PF09492.10 KKK12356.1 - 0.00093 18.6 3.5 0.54 9.5 0.0 3.9 3 1 1 5 5 5 2 Pectic acid lyase TSGP1 PF07771.11 KKK12356.1 - 0.018 15.2 0.0 0.037 14.2 0.0 1.4 1 0 0 1 1 1 0 Tick salivary peptide group 1 SIT PF15330.6 KKK12356.1 - 0.36 11.3 1.3 1.2 9.6 0.2 2.2 2 0 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT TP6A_N PF04406.14 KKK12357.1 - 2e-18 66.1 0.0 3.8e-18 65.2 0.0 1.5 1 0 0 1 1 1 1 Type IIB DNA topoisomerase UQ_con PF00179.26 KKK12358.1 - 1.5e-50 170.5 0.0 1.7e-50 170.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Ribosomal_L27 PF01016.19 KKK12359.1 - 2.5e-29 101.1 0.0 4.9e-29 100.2 0.0 1.5 1 0 0 1 1 1 1 Ribosomal L27 protein tRNA_int_endo PF01974.17 KKK12360.1 - 1.2e-19 70.1 1.0 4.8e-19 68.2 1.0 1.9 1 1 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.14 KKK12360.1 - 1.8e-06 27.5 0.0 0.017 14.8 0.0 2.3 2 0 0 2 2 2 2 tRNA intron endonuclease, N-terminal domain Cas_GSU0054 PF09609.10 KKK12360.1 - 0.071 11.8 0.0 0.14 10.8 0.0 1.4 2 0 0 2 2 2 0 CRISPR-associated protein, GSU0054 family (Cas_GSU0054) Nop10p PF04135.12 KKK12361.1 - 1.8e-24 85.5 0.9 2.1e-24 85.3 0.9 1.1 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family DUF3995 PF13160.6 KKK12362.1 - 0.33 11.3 8.3 3.6 8.0 1.1 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3995) DUF373 PF04123.13 KKK12362.1 - 0.66 9.4 2.7 0.92 8.9 2.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF373) NOB1_Zn_bind PF08772.11 KKK12363.1 - 6.1e-33 112.8 4.3 1.1e-32 112.0 4.3 1.4 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like PIN_6 PF17146.4 KKK12363.1 - 1.4e-30 105.6 0.1 5.2e-30 103.8 0.0 2.1 2 0 0 2 2 2 1 PIN domain of ribonuclease DZR PF12773.7 KKK12363.1 - 0.021 14.8 0.8 0.044 13.8 0.8 1.5 1 0 0 1 1 1 0 Double zinc ribbon zinc_ribbon_15 PF17032.5 KKK12363.1 - 0.024 15.4 0.7 0.048 14.4 0.7 1.5 1 0 0 1 1 1 0 zinc-ribbon family HypA PF01155.19 KKK12363.1 - 0.046 13.7 0.5 0.67 10.0 0.9 2.3 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-NADH-PPase PF09297.11 KKK12363.1 - 0.34 10.6 4.5 0.15 11.7 0.6 2.3 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain Zn-ribbon_8 PF09723.10 KKK12363.1 - 0.4 10.8 3.3 0.4 10.8 1.3 2.1 2 0 0 2 2 2 0 Zinc ribbon domain Scramblase PF03803.15 KKK12364.1 - 6.1e-54 182.6 1.0 4.7e-29 101.3 0.1 3.1 2 1 0 2 2 2 2 Scramblase Rad9_Rad53_bind PF08605.10 KKK12365.1 - 6.2e-32 110.5 0.0 9.6e-32 109.9 0.0 1.3 1 0 0 1 1 1 1 Fungal Rad9-like Rad53-binding Tudor_3 PF18115.1 KKK12365.1 - 5.8e-21 74.1 0.0 1.3e-20 73.0 0.0 1.6 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain BRCT_2 PF16589.5 KKK12365.1 - 6.1e-06 26.5 0.0 1.4e-05 25.4 0.0 1.7 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 KKK12365.1 - 0.00013 22.3 0.0 0.0012 19.2 0.0 2.6 2 1 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain RTT107_BRCT_5 PF16770.5 KKK12365.1 - 0.00025 20.9 0.0 0.00055 19.8 0.0 1.5 1 0 0 1 1 1 1 Regulator of Ty1 transposition protein 107 BRCT domain BRCT_3 PF18428.1 KKK12365.1 - 0.046 13.8 0.0 6.2 7.0 0.0 2.4 2 0 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain Las1 PF04031.13 KKK12366.1 - 2.7e-48 163.9 0.2 4.8e-48 163.1 0.2 1.4 1 0 0 1 1 1 1 Las1-like HAGH_C PF16123.5 KKK12366.1 - 4.5e-21 75.2 0.3 9.1e-21 74.2 0.3 1.5 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 KKK12366.1 - 4.4e-18 66.0 1.3 3.2e-12 46.9 0.1 2.4 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KKK12366.1 - 0.0035 16.9 0.9 0.019 14.5 0.9 2.2 1 1 0 1 1 1 1 Beta-lactamase superfamily domain BcrAD_BadFG PF01869.20 KKK12366.1 - 0.11 12.0 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family Peptidase_S24 PF00717.23 KKK12367.1 - 3.8e-05 23.6 0.0 6.7e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like S-antigen PF05756.11 KKK12368.1 - 0.0088 16.4 0.6 0.014 15.7 0.6 1.2 1 0 0 1 1 1 1 S-antigen protein Na_Ca_ex PF01699.24 KKK12369.1 - 4.7e-51 172.7 42.9 3.9e-27 95.1 16.9 2.6 2 0 0 2 2 2 2 Sodium/calcium exchanger protein BCAS2 PF05700.11 KKK12369.1 - 0.022 14.5 0.5 0.034 13.8 0.5 1.2 1 0 0 1 1 1 0 Breast carcinoma amplified sequence 2 (BCAS2) Herpes_gE PF02480.16 KKK12369.1 - 0.029 13.1 0.9 2.8 6.6 0.0 2.1 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E DUF4307 PF14155.6 KKK12369.1 - 1.9 8.4 3.4 4.2 7.2 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4307) Cnd2 PF05786.14 KKK12370.1 - 0 1042.9 0.7 0 1042.7 0.7 1.0 1 0 0 1 1 1 1 Condensin complex subunit 2 CNDH2_N PF06278.11 KKK12370.1 - 0.0084 16.3 0.0 0.025 14.8 0.0 1.8 1 0 0 1 1 1 1 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal Sde2_N_Ubi PF13019.6 KKK12370.1 - 0.25 11.1 1.1 0.5 10.2 1.1 1.4 1 0 0 1 1 1 0 Silencing defective 2 N-terminal ubiquitin domain FNIP_N PF14636.6 KKK12370.1 - 1.1 10.2 4.8 12 6.9 0.6 2.5 2 0 0 2 2 2 0 Folliculin-interacting protein N-terminus MARVEL PF01284.23 KKK12371.1 - 0.00064 19.8 6.1 0.0091 16.0 3.8 2.3 2 0 0 2 2 2 1 Membrane-associating domain DUF2339 PF10101.9 KKK12371.1 - 0.00097 17.9 2.6 0.0013 17.5 2.6 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2339) DUF981 PF06168.11 KKK12371.1 - 0.016 15.1 2.4 0.026 14.5 2.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF981) DUF202 PF02656.15 KKK12371.1 - 0.03 14.8 0.9 0.03 14.8 0.9 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF202) DUF4381 PF14316.6 KKK12371.1 - 0.044 14.0 3.2 4 7.7 0.5 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) SPC25 PF06703.11 KKK12371.1 - 0.065 13.0 1.5 0.18 11.5 1.5 1.8 1 0 0 1 1 1 0 Microsomal signal peptidase 25 kDa subunit (SPC25) FixQ PF05545.11 KKK12371.1 - 0.1 12.6 9.6 0.65 10.0 0.0 3.2 2 1 1 3 3 3 0 Cbb3-type cytochrome oxidase component FixQ PEN-2 PF10251.9 KKK12371.1 - 0.1 13.0 8.9 0.051 14.0 4.0 2.6 3 0 0 3 3 3 0 Presenilin enhancer-2 subunit of gamma secretase Cation_efflux PF01545.21 KKK12371.1 - 0.11 12.2 0.1 0.11 12.2 0.1 1.9 2 0 0 2 2 2 0 Cation efflux family DUF1772 PF08592.11 KKK12371.1 - 0.14 12.5 4.0 0.12 12.6 1.8 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF1772) DUF4199 PF13858.6 KKK12371.1 - 1.1 9.7 7.7 0.14 12.6 0.7 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF4199) DUF3413 PF11893.8 KKK12371.1 - 5.1 6.2 11.4 2.5 7.2 7.6 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF3413) DUF2721 PF11026.8 KKK12371.1 - 5.5 6.9 7.9 5.4 6.9 0.8 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2721) Ribosomal_S19 PF00203.21 KKK12380.1 - 3.6e-35 119.7 0.3 5e-35 119.2 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 SET PF00856.28 KKK12381.1 - 1.9e-13 51.1 0.0 2.4e-12 47.6 0.0 2.3 2 1 0 2 2 2 1 SET domain zf-MYND PF01753.18 KKK12381.1 - 2.8e-08 33.7 8.6 7.7e-08 32.3 8.7 1.7 1 1 0 1 1 1 1 MYND finger CPSase_L_D2 PF02786.17 KKK12382.1 - 3e-107 356.9 0.0 1.7e-83 279.3 0.0 2.2 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.19 KKK12382.1 - 8.8e-41 139.1 0.0 2.3e-40 137.7 0.0 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain Dala_Dala_lig_C PF07478.13 KKK12382.1 - 8.6e-18 64.6 0.1 5.1e-08 32.7 0.0 2.4 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 KKK12382.1 - 4.3e-17 62.2 0.0 4.2e-07 29.7 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.6 KKK12382.1 - 8.5e-12 45.0 0.0 8.6e-05 22.3 0.0 3.1 2 1 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_5 PF13549.6 KKK12382.1 - 1.2e-05 24.8 0.1 0.029 13.8 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain GARS_A PF01071.19 KKK12382.1 - 0.0012 18.6 0.0 0.21 11.4 0.0 2.5 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain DUF3439 PF11921.8 KKK12385.1 - 4.6 7.2 18.5 1.4 8.9 4.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) SPT2 PF08243.11 KKK12386.1 - 2.7e-06 27.9 21.2 7.9e-06 26.4 21.2 1.8 1 1 0 1 1 1 1 SPT2 chromatin protein Ribosomal_60s PF00428.19 KKK12387.1 - 8.4e-27 93.6 14.2 1.2e-26 93.1 14.2 1.2 1 0 0 1 1 1 1 60s Acidic ribosomal protein EGF_CA PF07645.15 KKK12388.1 - 0.0004 20.5 7.6 0.0004 20.5 7.6 2.0 2 0 0 2 2 2 1 Calcium-binding EGF domain EGF_3 PF12947.7 KKK12388.1 - 0.0034 17.5 5.4 0.0034 17.5 5.4 2.3 2 1 0 2 2 2 1 EGF domain FXa_inhibition PF14670.6 KKK12388.1 - 0.49 10.7 13.9 0.27 11.6 9.2 2.8 2 1 1 3 3 3 0 Coagulation Factor Xa inhibitory site cEGF PF12662.7 KKK12388.1 - 5.4 7.0 12.1 0.17 11.8 4.7 2.4 2 1 0 2 2 2 0 Complement Clr-like EGF-like Carb_kinase PF01256.17 KKK12389.1 - 3.9e-54 183.7 0.4 4.3e-53 180.3 0.4 2.0 1 1 0 1 1 1 1 Carbohydrate kinase DUF4148 PF13663.6 KKK12389.1 - 0.19 11.9 0.7 0.82 9.9 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4148) MCM PF00493.23 KKK12390.1 - 5.1e-104 346.3 0.0 8.9e-104 345.5 0.0 1.4 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KKK12390.1 - 2.8e-33 114.4 0.5 5e-33 113.6 0.5 1.3 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KKK12390.1 - 1.9e-21 76.3 0.4 5.2e-21 74.9 0.4 1.8 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KKK12390.1 - 8.3e-20 71.3 1.6 2.1e-19 70.0 1.6 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 KKK12390.1 - 5.7e-07 29.1 0.0 5.4e-05 22.7 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KKK12390.1 - 3.2e-06 27.2 0.0 9e-06 25.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 KKK12390.1 - 0.01 15.7 0.0 0.053 13.4 0.0 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_lid_2 PF17863.1 KKK12390.1 - 0.035 13.9 0.0 0.1 12.5 0.0 1.7 1 0 0 1 1 1 0 AAA lid domain Fungal_trans PF04082.18 KKK12391.1 - 1.3e-28 99.8 0.4 2.2e-28 99.0 0.3 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK12391.1 - 6.4e-09 35.8 11.4 1.5e-08 34.6 11.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CLZ PF16526.5 KKK12391.1 - 0.022 15.1 1.5 0.039 14.3 1.5 1.3 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels HALZ PF02183.18 KKK12391.1 - 0.046 13.9 4.4 0.085 13.1 4.4 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper TolA_bind_tri PF16331.5 KKK12391.1 - 0.13 12.3 8.7 0.24 11.5 8.7 1.3 1 0 0 1 1 1 0 TolA binding protein trimerisation DHR10 PF18595.1 KKK12391.1 - 0.46 10.6 3.4 0.76 9.9 3.4 1.3 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain AMP-binding PF00501.28 KKK12392.1 - 4.1e-96 322.2 0.0 4.8e-96 321.9 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KKK12392.1 - 2.4e-05 25.2 0.2 6.6e-05 23.8 0.2 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AAA PF00004.29 KKK12393.1 - 6.5e-54 181.9 0.0 3.9e-43 147.0 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.11 KKK12393.1 - 1.8e-29 102.0 0.8 3.8e-29 100.9 0.8 1.6 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_lid_3 PF17862.1 KKK12393.1 - 4e-15 55.3 0.4 5.9e-09 35.6 0.1 2.6 2 0 0 2 2 2 2 AAA+ lid domain AAA_2 PF07724.14 KKK12393.1 - 2.5e-06 27.7 0.0 0.074 13.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) NACHT PF05729.12 KKK12393.1 - 3.1e-06 27.2 4.7 0.0012 18.8 0.0 3.9 4 0 0 4 4 4 2 NACHT domain AAA_16 PF13191.6 KKK12393.1 - 3.9e-05 24.1 13.8 0.026 14.9 0.2 5.0 4 2 2 6 6 5 2 AAA ATPase domain RuvB_N PF05496.12 KKK12393.1 - 5.9e-05 22.9 0.0 0.0092 15.7 0.0 2.8 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain TsaE PF02367.17 KKK12393.1 - 0.00013 22.0 0.9 0.64 10.0 0.1 3.1 3 0 0 3 3 3 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE IstB_IS21 PF01695.17 KKK12393.1 - 0.00013 21.7 0.6 0.14 11.9 0.0 2.7 3 0 0 3 3 3 2 IstB-like ATP binding protein RNA_helicase PF00910.22 KKK12393.1 - 0.00021 21.6 0.3 9.1 6.7 0.0 4.1 4 0 0 4 4 4 0 RNA helicase AAA_18 PF13238.6 KKK12393.1 - 0.00024 21.6 0.1 0.8 10.3 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_14 PF13173.6 KKK12393.1 - 0.00041 20.4 0.0 1.9 8.5 0.0 3.1 2 1 0 2 2 2 2 AAA domain AAA_22 PF13401.6 KKK12393.1 - 0.00044 20.5 5.6 0.58 10.4 0.1 4.4 3 2 0 3 3 3 2 AAA domain AAA_5 PF07728.14 KKK12393.1 - 0.00053 20.0 0.1 0.95 9.5 0.0 3.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 KKK12393.1 - 0.00074 19.7 0.0 0.13 12.4 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 KKK12393.1 - 0.0033 17.0 0.0 0.23 11.0 0.0 2.7 2 0 0 2 2 2 1 P-loop containing dynein motor region TIP49 PF06068.13 KKK12393.1 - 0.0037 16.5 0.0 1.2 8.2 0.0 2.3 2 0 0 2 2 2 1 TIP49 P-loop domain PEX-2N PF09263.10 KKK12393.1 - 0.0039 17.5 0.0 3 8.2 0.0 2.6 2 0 0 2 2 2 1 Peroxisome biogenesis factor 1, N-terminal ATPase_2 PF01637.18 KKK12393.1 - 0.0067 16.4 1.6 7.2 6.5 0.0 4.0 4 1 0 4 4 3 0 ATPase domain predominantly from Archaea Zeta_toxin PF06414.12 KKK12393.1 - 0.012 14.9 1.7 2.1 7.6 0.0 2.7 3 0 0 3 3 3 0 Zeta toxin Mg_chelatase PF01078.21 KKK12393.1 - 0.017 14.5 1.8 0.18 11.1 0.1 3.0 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI DUF2075 PF09848.9 KKK12393.1 - 0.02 14.2 0.5 1.8 7.7 0.0 2.7 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.6 KKK12393.1 - 0.02 15.2 0.9 0.7 10.2 0.0 3.1 3 0 0 3 3 3 0 AAA domain Cytidylate_kin2 PF13189.6 KKK12393.1 - 0.022 14.9 0.1 4.8 7.3 0.0 3.1 3 0 0 3 3 3 0 Cytidylate kinase-like family Sigma54_activat PF00158.26 KKK12393.1 - 0.03 14.0 0.1 4.2 7.0 0.0 3.2 4 0 0 4 4 3 0 Sigma-54 interaction domain ATPase PF06745.13 KKK12393.1 - 0.032 13.6 2.5 1.3 8.3 0.1 3.0 3 0 0 3 3 3 0 KaiC AAA_28 PF13521.6 KKK12393.1 - 0.033 14.4 0.0 13 6.0 0.0 2.8 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 KKK12393.1 - 0.036 13.8 0.0 0.4 10.4 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase SKI PF01202.22 KKK12393.1 - 0.082 13.0 0.0 21 5.2 0.0 2.6 2 0 0 2 2 2 0 Shikimate kinase Sigma54_activ_2 PF14532.6 KKK12393.1 - 0.14 12.3 0.0 4.9 7.3 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain NTPase_1 PF03266.15 KKK12393.1 - 0.14 12.0 0.1 2 8.3 0.0 2.3 2 0 0 2 2 2 0 NTPase T2SSE PF00437.20 KKK12393.1 - 0.2 10.7 2.5 0.65 9.0 0.1 2.7 3 0 0 3 3 3 0 Type II/IV secretion system protein ABC_tran PF00005.27 KKK12393.1 - 0.62 10.6 4.5 24 5.5 0.0 3.7 4 0 0 4 4 4 0 ABC transporter AAA_29 PF13555.6 KKK12393.1 - 0.63 9.8 3.1 13 5.7 1.0 3.2 3 0 0 3 3 3 0 P-loop containing region of AAA domain AAA_25 PF13481.6 KKK12393.1 - 0.68 9.5 4.3 2.7 7.5 0.1 3.5 2 2 1 4 4 4 0 AAA domain Mito_carr PF00153.27 KKK12417.1 - 3.4e-40 135.9 2.1 7.1e-19 67.5 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Sod_Fe_C PF02777.18 KKK12418.1 - 2.1e-16 59.9 0.1 1.7e-13 50.6 0.1 2.3 1 1 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 KKK12418.1 - 0.048 14.1 0.1 0.088 13.3 0.1 1.4 1 0 0 1 1 1 0 Iron/manganese superoxide dismutases, alpha-hairpin domain FMN_dh PF01070.18 KKK12419.1 - 4.2e-106 354.9 0.0 6.3e-106 354.3 0.0 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 KKK12419.1 - 4.2e-20 71.7 0.0 9.7e-20 70.5 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 KKK12419.1 - 2.8e-06 26.7 0.0 4.3e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 KKK12419.1 - 5.9e-05 22.2 0.0 0.00018 20.7 0.0 1.7 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.21 KKK12419.1 - 0.019 14.4 0.0 0.047 13.2 0.0 1.5 1 0 0 1 1 1 0 Histidine biosynthesis protein NMO PF03060.15 KKK12419.1 - 0.12 11.7 0.2 0.2 11.0 0.2 1.3 1 0 0 1 1 1 0 Nitronate monooxygenase HlyIII PF03006.20 KKK12420.1 - 1.3e-60 204.9 19.9 1.6e-60 204.6 19.9 1.1 1 0 0 1 1 1 1 Haemolysin-III related Asr PF06392.11 KKK12420.1 - 0.059 13.8 1.0 0.13 12.7 1.0 1.5 1 0 0 1 1 1 0 Acid shock protein repeat FmiP_Thoc5 PF09766.9 KKK12421.1 - 3.7e-32 112.0 16.1 4.6e-32 111.7 16.1 1.1 1 0 0 1 1 1 1 Fms-interacting protein/Thoc5 SPATA1_C PF15743.5 KKK12421.1 - 0.006 16.7 6.2 0.015 15.4 3.2 2.2 2 0 0 2 2 2 1 Spermatogenesis-associated C-terminus DUF4200 PF13863.6 KKK12421.1 - 0.01 16.2 14.7 0.16 12.3 0.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) RNase_E_G PF10150.9 KKK12421.1 - 0.069 12.6 2.9 2.2 7.6 1.2 2.1 2 0 0 2 2 2 0 Ribonuclease E/G family Flagellin_N PF00669.20 KKK12421.1 - 0.11 12.5 2.3 0.15 12.1 0.5 1.8 2 0 0 2 2 2 0 Bacterial flagellin N-terminal helical region CwfJ_C_1 PF04677.15 KKK12421.1 - 0.13 12.2 1.2 0.52 10.2 0.4 2.2 1 1 2 3 3 3 0 Protein similar to CwfJ C-terminus 1 YabA PF06156.13 KKK12421.1 - 0.14 12.8 7.1 4 8.1 0.1 2.2 2 0 0 2 2 2 0 Initiation control protein YabA DUF2353 PF09789.9 KKK12421.1 - 0.25 10.7 15.9 3.9 6.7 15.9 2.0 1 1 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) DUF3450 PF11932.8 KKK12421.1 - 0.3 10.4 8.1 1.4 8.1 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) CREPT PF16566.5 KKK12421.1 - 0.37 11.0 10.7 3.5 7.8 2.0 3.1 2 1 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour Mod_r PF07200.13 KKK12421.1 - 0.4 10.8 15.2 1.3 9.1 6.0 2.4 2 1 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Rootletin PF15035.6 KKK12421.1 - 0.52 10.3 13.6 0.65 10.0 13.2 1.3 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion APG6_N PF17675.1 KKK12421.1 - 0.56 10.7 18.1 2.7 8.5 0.9 2.2 2 0 0 2 2 2 0 Apg6 coiled-coil region K-box PF01486.17 KKK12421.1 - 0.97 9.6 14.7 0.94 9.7 10.9 2.5 1 1 1 2 2 2 0 K-box region FUSC PF04632.12 KKK12421.1 - 1.2 7.6 5.4 1.6 7.2 5.4 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF4140 PF13600.6 KKK12421.1 - 1.7 9.1 7.2 6.5 7.3 0.1 2.4 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Casc1_N PF15927.5 KKK12421.1 - 5.5 6.6 17.5 0.23 11.1 10.6 2.0 2 0 0 2 2 2 0 Cancer susceptibility candidate 1 N-terminus PIG-S PF10510.9 KKK12422.1 - 1.5e-185 617.9 0.4 1.8e-185 617.7 0.4 1.0 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein DAD PF02109.16 KKK12423.1 - 0.054 13.8 0.0 0.1 13.0 0.0 1.4 1 0 0 1 1 1 0 DAD family Apt1 PF10351.9 KKK12423.1 - 0.55 9.0 6.1 0.7 8.7 6.1 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Fungal_trans PF04082.18 KKK12424.1 - 4.9e-21 75.0 1.8 6.6e-21 74.5 0.0 2.0 3 0 0 3 3 3 1 Fungal specific transcription factor domain Polyketide_cyc PF03364.20 KKK12424.1 - 5e-21 75.3 0.0 1.3e-20 74.0 0.0 1.7 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.9 KKK12424.1 - 0.0013 19.0 0.2 0.04 14.2 0.2 2.4 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Epimerase PF01370.21 KKK12425.1 - 3.4e-24 85.7 0.0 4.4e-24 85.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KKK12425.1 - 3.4e-22 78.7 0.0 4.5e-22 78.4 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KKK12425.1 - 8.6e-16 58.2 0.0 6.9e-15 55.3 0.0 1.9 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 KKK12425.1 - 1.3e-13 51.3 0.0 2e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 KKK12425.1 - 3.8e-09 36.1 0.0 4.9e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein NmrA PF05368.13 KKK12425.1 - 1.8e-07 31.0 0.0 8.4e-07 28.8 0.0 1.9 2 0 0 2 2 2 1 NmrA-like family Polysacc_synt_2 PF02719.15 KKK12425.1 - 0.00015 21.0 0.0 0.00023 20.4 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.25 KKK12425.1 - 0.0034 16.9 0.0 0.0064 16.0 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KKK12425.1 - 0.085 12.8 0.0 0.14 12.1 0.0 1.4 1 1 0 1 1 1 0 KR domain Fe-ADH PF00465.19 KKK12426.1 - 5.3e-35 120.9 3.4 8.1e-35 120.3 3.4 1.3 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fungal_trans PF04082.18 KKK12426.1 - 2.3e-14 53.0 0.3 3.6e-14 52.4 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fe-ADH_2 PF13685.6 KKK12426.1 - 1.8e-09 37.6 0.3 9.3e-09 35.3 0.4 1.9 2 0 0 2 2 2 1 Iron-containing alcohol dehydrogenase Zn_clus PF00172.18 KKK12426.1 - 1.3e-06 28.4 9.2 2.3e-06 27.6 9.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KKK12427.1 - 1.2e-27 96.6 0.0 2.3e-27 95.7 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain APH PF01636.23 KKK12428.1 - 3e-06 27.3 0.0 4.2e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KKK12428.1 - 4.3e-05 23.2 0.0 7.8e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.20 KKK12428.1 - 0.0027 17.1 0.0 0.0065 15.8 0.0 1.6 2 0 0 2 2 2 1 Ecdysteroid kinase DUF1679 PF07914.11 KKK12428.1 - 0.014 14.2 0.0 0.021 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) UCH PF00443.29 KKK12429.1 - 3.6e-46 157.7 0.0 5.4e-46 157.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KKK12429.1 - 1.1e-09 38.4 0.0 3.4e-05 23.6 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase ERG4_ERG24 PF01222.17 KKK12430.1 - 5.1e-139 463.7 20.2 6.6e-139 463.4 20.2 1.1 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DLH PF01738.18 KKK12430.1 - 9.1e-28 97.3 0.0 1.5e-27 96.6 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family zf-C3HC4 PF00097.25 KKK12430.1 - 4e-07 29.8 7.2 8.4e-07 28.8 7.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KKK12430.1 - 1.9e-06 27.6 5.0 4.5e-06 26.4 5.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KKK12430.1 - 3.7e-06 26.7 4.8 3e-05 23.8 1.8 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KKK12430.1 - 7.7e-06 25.8 3.6 7.7e-06 25.8 3.6 2.3 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 KKK12430.1 - 1.1e-05 25.6 8.1 6.1e-05 23.3 8.1 2.2 1 1 1 2 2 2 1 Ring finger domain zf-C3HC4_4 PF15227.6 KKK12430.1 - 1.9e-05 24.7 5.0 8.9e-05 22.6 5.3 2.1 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 KKK12430.1 - 3.9e-05 23.5 4.1 9.1e-05 22.3 4.1 1.7 1 0 0 1 1 1 1 zinc-RING finger domain BAAT_C PF08840.11 KKK12430.1 - 0.0064 16.4 0.0 1.9 8.3 0.0 2.5 1 1 1 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S15 PF02129.18 KKK12430.1 - 0.05 13.2 0.0 0.12 11.9 0.0 1.6 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) LIDHydrolase PF10230.9 KKK12430.1 - 0.071 12.6 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Prok-RING_4 PF14447.6 KKK12430.1 - 0.1 12.5 7.9 0.45 10.4 7.7 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 KKK12430.1 - 1.4 9.3 4.3 3.6 7.9 4.3 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_10 PF16685.5 KKK12430.1 - 2.9 8.1 4.4 7 6.9 4.4 1.7 1 0 0 1 1 1 0 zinc RING finger of MSL2 Chs7 PF12271.8 KKK12431.1 - 1.1e-110 369.5 5.2 1.3e-110 369.4 5.2 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone DUF4149 PF13664.6 KKK12431.1 - 0.063 13.6 1.0 0.063 13.6 1.0 3.0 3 1 0 3 3 3 0 Domain of unknown function (DUF4149) Gemini_mov PF01708.16 KKK12431.1 - 4.4 7.1 9.1 7.6 6.4 0.1 3.3 3 0 0 3 3 3 0 Geminivirus putative movement protein Aminotran_1_2 PF00155.21 KKK12433.1 - 4e-42 144.7 0.0 4.9e-42 144.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KKK12433.1 - 6.3e-09 35.3 0.0 1.1e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 KKK12433.1 - 7.2e-07 28.1 0.0 1e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 KKK12433.1 - 0.00072 18.9 0.0 0.0011 18.3 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Alliinase_C PF04864.13 KKK12433.1 - 0.13 11.1 0.0 0.24 10.3 0.0 1.3 1 1 0 1 1 1 0 Allinase AMP-binding PF00501.28 KKK12434.1 - 8.9e-61 205.7 0.0 2.9e-60 204.0 0.0 1.7 2 0 0 2 2 2 1 AMP-binding enzyme AMP-binding_C PF13193.6 KKK12434.1 - 2.4e-06 28.4 0.0 5.3e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Autoind_bind PF03472.15 KKK12434.1 - 0.072 12.6 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 Autoinducer binding domain APH PF01636.23 KKK12435.1 - 1e-08 35.4 0.3 5.4e-08 33.1 0.1 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family dCMP_cyt_deam_1 PF00383.23 KKK12436.1 - 2.8e-05 23.9 0.0 0.033 14.0 0.1 2.3 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region Cyclin PF08613.11 KKK12437.1 - 8.3e-33 114.0 1.0 3.3e-32 112.1 1.0 1.9 1 1 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 KKK12437.1 - 0.00015 21.5 0.0 0.00024 20.9 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain DUF3636 PF12331.8 KKK12438.1 - 1.3e-55 187.3 0.0 2.4e-55 186.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3636) LCD1 PF09798.9 KKK12438.1 - 3.4e-05 22.6 2.8 0.14 10.7 0.1 3.1 2 1 1 3 3 3 3 DNA damage checkpoint protein Nup54_57_C PF18570.1 KKK12438.1 - 0.0025 17.4 0.0 0.0063 16.1 0.0 1.6 1 0 0 1 1 1 1 NUP57/Nup54 C-terminal domain S4 PF01479.25 KKK12439.1 - 4.3e-15 55.2 0.0 8.1e-15 54.3 0.0 1.5 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.6 KKK12439.1 - 0.065 13.1 0.0 0.21 11.4 0.0 1.8 2 0 0 2 2 2 0 S4 domain RNA_pol_Rpc4 PF05132.14 KKK12439.1 - 0.31 11.5 11.8 0.18 12.2 0.6 2.3 2 0 0 2 2 2 0 RNA polymerase III RPC4 DUF722 PF05263.11 KKK12439.1 - 0.82 9.9 4.0 1.2 9.3 1.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF722) CPSF100_C PF13299.6 KKK12439.1 - 2.1 8.5 12.2 0.16 12.1 1.4 2.3 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal CTP_transf_1 PF01148.20 KKK12440.1 - 2.9e-80 269.8 23.1 3.6e-80 269.6 23.1 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family TFIIA PF03153.13 KKK12441.1 - 1.9 8.4 31.3 0.16 12.0 19.9 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit SelP_N PF04592.14 KKK12441.1 - 2.5 7.4 33.4 0.089 12.2 25.5 2.1 2 0 0 2 2 2 0 Selenoprotein P, N terminal region Cyclin_N PF00134.23 KKK12442.1 - 2.2e-09 37.1 0.1 1.9e-07 30.9 0.0 2.4 1 1 1 2 2 2 2 Cyclin, N-terminal domain RPA43_OB PF17875.1 KKK12442.1 - 0.31 11.7 1.3 0.58 10.8 1.3 1.4 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I Arm PF00514.23 KKK12443.1 - 8.3e-18 63.8 1.5 0.001 19.1 0.0 8.4 8 0 0 8 8 8 4 Armadillo/beta-catenin-like repeat HEAT PF02985.22 KKK12443.1 - 6.5e-06 26.0 3.3 6.3 7.3 0.0 6.6 6 0 0 6 6 6 2 HEAT repeat HEAT_2 PF13646.6 KKK12443.1 - 0.0049 17.2 0.3 3.5 8.1 0.0 4.4 4 1 0 4 4 4 1 HEAT repeats HEAT_EZ PF13513.6 KKK12443.1 - 0.088 13.3 3.5 30 5.2 0.0 5.1 6 0 0 6 6 6 0 HEAT-like repeat DUF1494 PF07379.11 KKK12443.1 - 0.17 11.7 0.1 0.43 10.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1494) Aldo_ket_red PF00248.21 KKK12444.1 - 2.7e-61 207.3 0.0 3.1e-61 207.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Ank_5 PF13857.6 KKK12445.1 - 0.0022 18.2 0.1 3.5 8.1 0.0 2.6 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 KKK12445.1 - 0.013 16.0 0.1 11 6.8 0.0 3.0 3 0 0 3 3 3 0 Ankyrin repeats (many copies) Ank_2 PF12796.7 KKK12445.1 - 0.054 14.1 0.0 0.34 11.5 0.0 2.0 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) Fox-1_C PF12414.8 KKK12445.1 - 0.11 12.9 0.0 0.21 12.0 0.0 1.4 1 0 0 1 1 1 0 Calcitonin gene-related peptide regulator C terminal Ank_3 PF13606.6 KKK12445.1 - 0.25 12.0 0.8 71 4.5 0.0 3.3 4 0 0 4 4 4 0 Ankyrin repeat CorA PF01544.18 KKK12447.1 - 1.5e-10 40.9 1.2 1.2e-09 37.9 0.1 2.1 1 1 1 2 2 2 1 CorA-like Mg2+ transporter protein CK2S PF15011.6 KKK12447.1 - 0.2 11.5 1.7 19 5.1 0.0 2.6 2 1 0 2 2 2 0 Casein Kinase 2 substrate Ge1_WD40 PF16529.5 KKK12448.1 - 0.0083 15.1 0.0 0.028 13.4 0.0 1.7 1 1 0 1 1 1 1 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF4193 PF13834.6 KKK12448.1 - 0.25 11.8 1.6 0.8 10.2 0.8 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4193) DUF2884 PF11101.8 KKK12448.1 - 0.29 10.6 12.0 0.053 13.0 3.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2884) RNase_H PF00075.24 KKK12449.1 - 1e-37 129.5 0.0 1.6e-37 128.8 0.0 1.2 1 0 0 1 1 1 1 RNase H Cauli_VI PF01693.16 KKK12449.1 - 2.8e-37 126.7 15.2 4.2e-19 68.6 1.8 2.4 2 0 0 2 2 2 2 Caulimovirus viroplasmin RVT_3 PF13456.6 KKK12449.1 - 0.025 14.4 0.0 0.052 13.4 0.0 1.6 1 0 0 1 1 1 0 Reverse transcriptase-like Na_H_Exchanger PF00999.21 KKK12450.1 - 5.5e-47 160.4 19.3 7e-47 160.0 19.3 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family RIH_assoc PF08454.11 KKK12451.1 - 0.05 13.5 0.1 0.99 9.3 0.0 2.9 2 0 0 2 2 2 0 RyR and IP3R Homology associated HEAT PF02985.22 KKK12451.1 - 0.1 12.9 1.5 35 5.0 0.1 4.3 3 0 0 3 3 3 0 HEAT repeat APC_u9 PF16633.5 KKK12451.1 - 0.12 13.4 0.0 0.5 11.5 0.0 2.1 1 0 0 1 1 1 0 Unstructured region on APC between 1st two creatine-rich regions Glyco_hydro_35 PF01301.19 KKK12451.1 - 0.13 11.8 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 35 HEAT_EZ PF13513.6 KKK12451.1 - 0.55 10.8 2.8 2.4 8.8 0.6 3.0 2 0 0 2 2 2 0 HEAT-like repeat DNA_ligase_A_M PF01068.21 KKK12452.1 - 1.1e-52 178.7 0.9 1.4e-50 171.8 0.9 2.3 1 1 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 KKK12452.1 - 2.4e-31 109.4 0.0 7.6e-30 104.5 0.0 2.6 1 1 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 KKK12452.1 - 2.3e-27 95.5 0.0 6.4e-27 94.1 0.0 1.8 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 KKK12452.1 - 5.8e-05 23.5 0.1 0.0001 22.6 0.1 1.4 1 0 0 1 1 1 1 RNA ligase Synaptonemal_3 PF15191.6 KKK12452.1 - 0.11 12.3 0.0 0.36 10.6 0.0 1.9 1 0 0 1 1 1 0 Synaptonemal complex central element protein 3 CDC45 PF02724.14 KKK12452.1 - 8.7 4.5 11.7 15 3.7 11.7 1.4 1 0 0 1 1 1 0 CDC45-like protein eIF-5_eIF-2B PF01873.17 KKK12453.1 - 4e-39 133.1 0.0 8.3e-39 132.1 0.0 1.5 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.18 KKK12453.1 - 5e-22 77.8 0.3 1.4e-21 76.4 0.3 1.8 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon RSN1_7TM PF02714.15 KKK12454.1 - 3.7e-82 275.7 32.2 6.1e-82 275.0 32.2 1.4 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 KKK12454.1 - 7.1e-46 155.8 0.3 7.1e-46 155.8 0.3 3.5 4 1 0 4 4 4 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 KKK12454.1 - 9.6e-30 104.1 1.9 2.4e-18 67.0 0.1 2.8 3 0 0 3 3 3 2 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 KKK12454.1 - 3.2e-13 49.6 0.0 8.4e-13 48.3 0.0 1.7 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter MCM PF00493.23 KKK12455.1 - 6.5e-102 339.4 0.0 9.7e-102 338.8 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain VTC PF09359.10 KKK12455.1 - 3.2e-98 328.5 0.1 8e-98 327.2 0.0 1.8 2 0 0 2 2 2 1 VTC domain MCM_OB PF17207.3 KKK12455.1 - 2.6e-39 134.0 1.6 5.4e-39 132.9 1.6 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KKK12455.1 - 9.2e-29 99.7 3.8 9.6e-29 99.7 1.1 2.5 3 0 0 3 3 2 1 MCM AAA-lid domain MCM_N PF14551.6 KKK12455.1 - 2.9e-18 66.4 0.1 1.2e-17 64.3 0.1 2.2 1 0 0 1 1 1 1 MCM N-terminal domain DUF202 PF02656.15 KKK12455.1 - 2.5e-12 47.1 4.2 2.5e-12 47.1 4.2 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF202) SPX PF03105.19 KKK12455.1 - 8.6e-08 32.5 1.3 2.4e-05 24.4 0.0 5.3 4 2 1 5 5 4 3 SPX domain Mg_chelatase PF01078.21 KKK12455.1 - 1.5e-05 24.5 0.0 0.00027 20.4 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KKK12455.1 - 3.4e-05 23.9 0.0 9.3e-05 22.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 KKK12455.1 - 0.0019 18.0 0.0 0.0044 16.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF999 PF06198.11 KKK12455.1 - 1.4 8.9 4.5 20 5.2 0.5 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF999) Band_7 PF01145.25 KKK12456.1 - 1.7e-23 83.5 2.9 2.5e-23 83.0 2.9 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family Methyltransf_25 PF13649.6 KKK12457.1 - 0.0057 17.3 0.1 0.02 15.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain DUF429 PF04250.13 KKK12457.1 - 0.0084 15.9 1.3 0.26 11.1 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF429) Ank_4 PF13637.6 KKK12457.1 - 0.018 15.6 0.0 2.6 8.7 0.0 2.5 2 0 0 2 2 2 0 Ankyrin repeats (many copies) BUD22 PF09073.10 KKK12457.1 - 0.058 12.7 2.0 0.087 12.2 2.0 1.2 1 0 0 1 1 1 0 BUD22 CCDC53 PF10152.9 KKK12457.1 - 0.41 11.1 3.9 2.3 8.6 0.2 2.2 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex Spt5_N PF11942.8 KKK12457.1 - 1.8 9.6 12.8 8.2 7.5 2.9 2.4 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Lyase_aromatic PF00221.19 KKK12458.1 - 6.2e-154 513.1 5.2 8e-154 512.7 5.2 1.1 1 0 0 1 1 1 1 Aromatic amino acid lyase CSTF2_hinge PF14327.6 KKK12459.1 - 4.9e-33 113.4 2.2 4.9e-33 113.4 2.2 2.1 3 0 0 3 3 3 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.22 KKK12459.1 - 1.4e-19 69.7 0.0 2.2e-19 69.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.6 KKK12459.1 - 4.5e-16 58.2 17.8 5.7e-16 57.8 13.6 2.9 2 0 0 2 2 2 1 Transcription termination and cleavage factor C-terminal RRM_7 PF16367.5 KKK12459.1 - 0.0092 16.1 0.1 0.78 9.9 0.0 2.5 1 1 1 2 2 2 1 RNA recognition motif RRM_occluded PF16842.5 KKK12459.1 - 0.014 15.2 0.0 0.041 13.7 0.0 1.7 1 1 0 1 1 1 0 Occluded RNA-recognition motif Spo7_2_N PF15407.6 KKK12459.1 - 0.029 14.0 0.0 0.057 13.1 0.0 1.4 1 0 0 1 1 1 0 Sporulation protein family 7 RRM_Rrp7 PF17799.1 KKK12459.1 - 0.036 13.9 0.0 3.4 7.4 0.0 2.2 1 1 1 2 2 2 0 Rrp7 RRM-like N-terminal domain RRM_5 PF13893.6 KKK12459.1 - 0.11 12.1 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 2Fe-2S_thioredx PF01257.19 KKK12460.1 - 9.8e-26 90.3 0.1 1.2e-25 90.1 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin HSP9_HSP12 PF04119.12 KKK12460.1 - 0.088 13.2 0.0 0.16 12.4 0.0 1.4 1 0 0 1 1 1 0 Heat shock protein 9/12 SNF2_N PF00176.23 KKK12461.1 - 4.3e-19 68.5 0.7 6.1e-12 44.9 0.0 2.4 2 0 0 2 2 2 2 SNF2 family N-terminal domain DNA_methylase PF00145.17 KKK12461.1 - 1.8e-17 63.7 0.0 3.7e-17 62.7 0.0 1.6 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase Helicase_C PF00271.31 KKK12461.1 - 3e-06 27.5 0.0 8.8e-06 26.0 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Prok-RING_4 PF14447.6 KKK12461.1 - 0.0048 16.7 4.3 0.0048 16.7 4.3 2.5 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 KKK12461.1 - 0.18 11.7 9.4 0.9 9.4 2.2 2.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) IBR PF01485.21 KKK12461.1 - 0.25 11.6 9.8 1.3 9.3 3.5 2.8 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain zf-RING_5 PF14634.6 KKK12461.1 - 0.45 10.5 24.2 0.0081 16.1 6.5 2.9 3 0 0 3 3 3 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 KKK12461.1 - 0.87 9.7 11.6 0.83 9.7 2.9 2.7 2 0 0 2 2 2 0 RING-type zinc-finger Utp14 PF04615.13 KKK12470.1 - 0.22 10.0 62.8 0.29 9.6 62.8 1.1 1 0 0 1 1 1 0 Utp14 protein ERG2_Sigma1R PF04622.12 KKK12472.1 - 1.5e-71 240.1 0.1 2.1e-70 236.4 0.1 2.2 1 1 0 1 1 1 1 ERG2 and Sigma1 receptor like protein ATP_bind_3 PF01171.20 KKK12472.1 - 5.4e-18 65.4 0.0 1e-17 64.5 0.0 1.5 1 0 0 1 1 1 1 PP-loop family zn-ribbon_14 PF16503.5 KKK12472.1 - 1.1e-17 63.2 3.7 1.1e-17 63.2 3.7 3.0 4 0 0 4 4 4 1 Zinc-ribbon RecR PF02132.15 KKK12472.1 - 0.0071 15.9 1.1 0.0071 15.9 1.1 2.5 3 0 0 3 3 3 1 RecR protein Glyco_hydro_12 PF01670.16 KKK12473.1 - 7.3e-46 156.8 7.1 8.5e-46 156.6 7.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 APH PF01636.23 KKK12474.1 - 4e-06 26.9 0.0 1.6e-05 25.0 0.1 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KKK12474.1 - 0.0087 15.7 0.0 0.015 14.9 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase RasGEF PF00617.19 KKK12475.1 - 4.8e-44 150.7 0.3 1e-43 149.6 0.1 1.7 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 KKK12475.1 - 6e-15 55.4 0.5 1.5e-14 54.1 0.5 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif Complex1_LYR_2 PF13233.6 KKK12475.1 - 2.9e-13 50.4 0.0 1e-12 48.6 0.0 2.0 1 0 0 1 1 1 1 Complex1_LYR-like Cadherin_pro PF08758.11 KKK12475.1 - 0.026 14.7 0.0 0.094 12.9 0.0 1.9 2 0 0 2 2 2 0 Cadherin prodomain like p47_phox_C PF08944.11 KKK12475.1 - 0.54 9.7 4.2 0.21 11.0 0.2 2.3 2 0 0 2 2 2 0 NADPH oxidase subunit p47Phox, C terminal domain Nfu_N PF08712.11 KKK12476.1 - 5.2e-30 103.4 0.1 1.7e-29 101.7 0.0 1.9 3 0 0 3 3 3 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.17 KKK12476.1 - 1.2e-27 95.8 0.2 2.4e-27 94.8 0.2 1.5 1 0 0 1 1 1 1 NifU-like domain zf-HIT PF04438.16 KKK12477.1 - 2e-09 37.2 7.4 3.3e-09 36.5 7.4 1.4 1 0 0 1 1 1 1 HIT zinc finger PolC_DP2 PF03833.13 KKK12477.1 - 0.32 8.8 1.2 0.31 8.9 1.2 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 zf-B_box PF00643.24 KKK12477.1 - 1.1 9.5 7.8 2.1 8.6 7.8 1.4 1 0 0 1 1 1 0 B-box zinc finger Ribosomal_L15e PF00827.17 KKK12478.1 - 1.4e-89 298.9 10.7 1.7e-89 298.6 10.7 1.0 1 0 0 1 1 1 1 Ribosomal L15 PSP1 PF04468.12 KKK12479.1 - 5.4e-28 97.1 2.6 9e-28 96.4 2.6 1.4 1 0 0 1 1 1 1 PSP1 C-terminal conserved region ADH_N PF08240.12 KKK12480.1 - 1.7e-35 121.2 2.4 1.5e-34 118.2 2.5 2.2 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KKK12480.1 - 5.6e-14 52.2 0.0 9.1e-14 51.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KKK12480.1 - 9.8e-12 44.8 0.0 1.5e-11 44.2 0.0 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 KKK12480.1 - 5.4e-06 27.5 0.0 9.2e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_7 PF13241.6 KKK12480.1 - 0.0033 17.8 0.0 0.0063 16.9 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding FAD_binding_3 PF01494.19 KKK12480.1 - 0.0082 15.4 0.5 0.013 14.7 0.5 1.2 1 0 0 1 1 1 1 FAD binding domain XdhC_C PF13478.6 KKK12480.1 - 0.071 13.6 0.0 0.11 13.0 0.0 1.3 1 0 0 1 1 1 0 XdhC Rossmann domain HECT PF00632.25 KKK12481.1 - 3.2e-55 187.8 0.0 3.9e-54 184.2 0.0 2.4 1 1 0 1 1 1 1 HECT-domain (ubiquitin-transferase) AJAP1_PANP_C PF15298.6 KKK12481.1 - 0.041 14.1 0.3 0.19 11.9 0.0 2.1 2 0 0 2 2 2 0 AJAP1/PANP C-terminus DUF1658 PF07871.11 KKK12481.1 - 0.046 13.6 1.7 0.27 11.2 1.7 2.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1658) Acetyltransf_8 PF13523.6 KKK12482.1 - 1.8e-52 176.9 0.0 2.8e-52 176.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KKK12482.1 - 0.0011 19.6 0.0 0.0027 18.4 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain OCD_Mu_crystall PF02423.15 KKK12483.1 - 1e-10 41.1 0.0 1.4e-09 37.3 0.0 2.8 2 1 0 2 2 2 1 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.20 KKK12483.1 - 1.1e-07 32.0 0.1 6.3e-06 26.3 0.0 2.6 2 1 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase GFO_IDH_MocA PF01408.22 KKK12483.1 - 0.14 13.0 0.0 0.3 11.9 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Cyclin_N PF00134.23 KKK12484.1 - 2.5e-12 46.7 0.0 4.7e-12 45.8 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 KKK12484.1 - 3.3e-07 30.8 0.1 1.1e-06 29.1 0.0 1.9 2 0 0 2 2 2 1 Cyclin FRG1 PF06229.12 KKK12485.1 - 6e-09 35.9 0.0 1e-08 35.2 0.0 1.4 1 0 0 1 1 1 1 FRG1-like domain DGF-1_C PF11040.8 KKK12485.1 - 0.069 13.1 0.8 0.15 12.1 0.5 1.6 2 0 0 2 2 2 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus Reg_prop PF07494.11 KKK12485.1 - 0.13 12.6 0.0 1.6 9.2 0.0 2.3 2 0 0 2 2 2 0 Two component regulator propeller DSBA PF01323.20 KKK12487.1 - 5.1e-13 49.2 0.0 5.9e-13 49.0 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Glyco_hydro_18 PF00704.28 KKK12489.1 - 1.8e-74 251.3 0.0 2.3e-74 250.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 KKK12489.1 - 9.6e-09 35.6 16.6 2e-08 34.6 16.6 1.5 1 0 0 1 1 1 1 Chitin recognition protein Metal_resist PF13801.6 KKK12490.1 - 0.096 12.9 0.1 0.096 12.9 0.1 1.8 2 0 0 2 2 2 0 Heavy-metal resistance DUF3328 PF11807.8 KKK12491.1 - 3.8e-27 95.5 0.0 6.3e-27 94.8 0.0 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) Glyco_hydro_20 PF00728.22 KKK12492.1 - 1.4e-102 343.7 0.8 1.8e-102 343.4 0.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 KKK12492.1 - 4.7e-28 98.5 0.0 1e-27 97.5 0.0 1.6 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 KKK12492.1 - 5.2e-05 24.0 0.0 0.00011 23.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 DUF3824 PF12868.7 KKK12502.1 - 5.9e-32 111.4 39.3 5.9e-32 111.4 39.3 8.0 5 1 4 9 9 9 4 Domain of unknwon function (DUF3824) YdjM PF04307.14 KKK12502.1 - 0.082 12.2 0.4 1.2 8.4 0.0 2.4 2 0 0 2 2 2 0 LexA-binding, inner membrane-associated putative hydrolase UCR_TM PF02921.14 KKK12502.1 - 0.84 10.2 14.2 6.7 7.3 0.1 5.2 4 1 0 4 4 4 0 Ubiquinol cytochrome reductase transmembrane region Cupin_8 PF13621.6 KKK12503.1 - 6.9e-33 114.4 0.1 1.2e-32 113.6 0.1 1.4 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 KKK12503.1 - 1.5e-07 31.2 0.0 0.0015 18.0 0.0 2.3 2 0 0 2 2 2 2 Cupin superfamily protein JmjC PF02373.22 KKK12503.1 - 0.0009 19.7 0.0 0.002 18.6 0.0 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_2 PF07883.11 KKK12503.1 - 0.083 12.6 0.0 0.22 11.3 0.0 1.7 1 0 0 1 1 1 0 Cupin domain MFS_1 PF07690.16 KKK12504.1 - 5.9e-37 127.4 14.8 6.9e-29 100.9 0.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KKK12504.1 - 5.2e-10 38.8 4.8 1.1e-09 37.7 4.8 1.5 1 0 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 KKK12504.1 - 0.0085 14.6 0.4 0.013 14.0 0.4 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) GTP1_OBG PF01018.22 KKK12505.1 - 8.5e-41 139.1 3.2 2.8e-30 104.9 4.4 2.2 2 0 0 2 2 2 2 GTP1/OBG MMR_HSR1 PF01926.23 KKK12505.1 - 6.8e-24 84.1 0.0 2.1e-23 82.6 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KKK12505.1 - 1.6e-08 34.3 0.1 3.9e-08 33.0 0.1 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B MeaB PF03308.16 KKK12505.1 - 7.5e-05 21.8 0.0 0.11 11.5 0.0 2.2 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB ABC_tran PF00005.27 KKK12505.1 - 0.02 15.4 1.7 0.053 14.0 0.0 2.1 2 0 0 2 2 2 0 ABC transporter GTP_EFTU PF00009.27 KKK12505.1 - 0.021 14.4 0.0 6.2 6.3 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Ploopntkinase3 PF18751.1 KKK12505.1 - 0.12 12.2 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 Dynamin_N PF00350.23 KKK12505.1 - 0.13 12.3 0.0 2.3 8.2 0.1 2.2 1 1 0 2 2 2 0 Dynamin family DnaJ PF00226.31 KKK12506.1 - 2.7e-22 78.6 0.3 5.6e-22 77.6 0.3 1.6 1 0 0 1 1 1 1 DnaJ domain Fungal_trans PF04082.18 KKK12507.1 - 1.6e-24 86.4 0.0 2.6e-24 85.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK12507.1 - 8e-09 35.5 12.6 1.3e-08 34.9 12.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Adenylsucc_synt PF00709.21 KKK12508.1 - 6e-153 509.7 0.0 2.5e-136 454.9 0.0 2.0 1 1 1 2 2 2 2 Adenylosuccinate synthetase KHA PF11834.8 KKK12508.1 - 0.047 13.8 0.0 0.12 12.4 0.0 1.7 1 0 0 1 1 1 0 KHA, dimerisation domain of potassium ion channel DEAD PF00270.29 KKK12509.1 - 2.9e-45 154.2 0.0 6e-45 153.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KKK12509.1 - 6e-20 71.6 0.1 1.9e-18 66.8 0.0 3.2 3 1 1 4 4 4 1 Helicase conserved C-terminal domain ResIII PF04851.15 KKK12509.1 - 3.9e-05 23.7 0.0 0.00014 22.0 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KKK12509.1 - 0.0054 16.0 0.0 0.0092 15.2 0.0 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase AAA_22 PF13401.6 KKK12509.1 - 0.021 15.1 0.5 0.15 12.3 0.0 2.6 3 1 0 3 3 3 0 AAA domain SecA_DEAD PF07517.14 KKK12509.1 - 0.11 11.8 0.0 0.41 9.9 0.0 1.9 2 0 0 2 2 2 0 SecA DEAD-like domain Bac_rhamnosid PF05592.11 KKK12514.1 - 0.027 14.4 0.0 0.064 13.2 0.0 1.6 1 0 0 1 1 1 0 Bacterial alpha-L-rhamnosidase concanavalin-like domain MFS_1 PF07690.16 KKK12515.1 - 2.2e-50 171.6 39.3 3.1e-50 171.1 39.3 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KKK12515.1 - 6.5e-13 48.4 16.1 6.5e-13 48.4 16.1 2.8 2 1 1 3 3 3 1 Sugar (and other) transporter OATP PF03137.20 KKK12515.1 - 0.00017 20.1 6.7 0.00017 20.1 6.7 2.6 2 1 1 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family DUF2583 PF10762.9 KKK12515.1 - 3.7 8.0 6.5 0.75 10.3 1.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2583) MFS_1 PF07690.16 KKK12516.1 - 2.3e-30 105.7 33.2 2.3e-30 105.7 33.2 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KKK12516.1 - 1.5e-12 47.2 6.1 1.5e-12 47.2 6.1 2.8 2 1 0 2 2 2 1 Sugar (and other) transporter Beta-lactamase PF00144.24 KKK12517.1 - 7.3e-39 133.9 0.0 2.1e-38 132.4 0.0 1.7 1 1 0 1 1 1 1 Beta-lactamase FAD_binding_4 PF01565.23 KKK12517.1 - 1.7e-30 105.6 0.1 2.7e-30 104.9 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KKK12517.1 - 0.00021 21.3 0.3 0.0035 17.4 0.2 2.4 2 0 0 2 2 2 1 Berberine and berberine like MFS_1 PF07690.16 KKK12518.1 - 2.9e-30 105.4 28.6 2.9e-30 105.4 28.6 1.8 2 1 1 3 3 3 1 Major Facilitator Superfamily DUF1993 PF09351.10 KKK12520.1 - 2.5e-53 180.5 0.0 2.7e-53 180.4 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) LdpA_C PF12617.8 KKK12520.1 - 0.15 11.7 0.0 0.22 11.1 0.0 1.2 1 0 0 1 1 1 0 Iron-Sulfur binding protein C terminal Peptidase_M43 PF05572.13 KKK12521.1 - 6.6e-11 42.4 0.3 1.4e-10 41.3 0.3 1.5 1 1 0 1 1 1 1 Pregnancy-associated plasma protein-A Peptidase_M10 PF00413.24 KKK12521.1 - 0.023 14.5 0.0 0.03 14.2 0.0 1.2 1 0 0 1 1 1 0 Matrixin Reprolysin_3 PF13582.6 KKK12521.1 - 0.066 13.7 0.0 0.2 12.1 0.0 1.8 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 KKK12521.1 - 0.069 12.8 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 KKK12521.1 - 0.24 11.5 0.6 1.1 9.4 0.4 2.0 1 1 0 1 1 1 0 Metallo-peptidase family M12 Abhydrolase_6 PF12697.7 KKK12522.1 - 2.8e-15 57.5 0.1 3.7e-15 57.1 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KKK12522.1 - 4.5e-11 42.9 0.1 2.3e-10 40.5 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KKK12522.1 - 5.1e-11 42.3 0.0 6.5e-11 42.0 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 KKK12522.1 - 0.0094 16.1 0.1 0.014 15.5 0.1 1.5 1 1 0 1 1 1 1 Thioesterase domain PGAP1 PF07819.13 KKK12522.1 - 0.016 14.9 0.0 0.027 14.2 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_8 PF06259.12 KKK12522.1 - 0.054 13.1 0.0 0.13 11.9 0.0 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase NAD_binding_1 PF00175.21 KKK12523.1 - 2.8e-24 85.9 0.0 4.3e-24 85.3 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KKK12523.1 - 3.7e-14 52.9 0.0 6e-14 52.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 KKK12523.1 - 6.3e-06 26.4 0.0 0.0048 17.0 0.0 2.2 1 1 1 2 2 2 2 Ferric reductase NAD binding domain MFS_1 PF07690.16 KKK12524.1 - 1.1e-10 41.0 0.2 1.6e-10 40.5 0.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily LacY_symp PF01306.19 KKK12524.1 - 0.048 12.4 0.4 0.26 10.0 0.6 1.9 2 0 0 2 2 2 0 LacY proton/sugar symporter HKR_ArcB_TM PF18415.1 KKK12524.1 - 2.2 9.1 6.2 0.79 10.6 0.1 2.8 3 0 0 3 3 3 0 Histidine kinase receptor ArcB trans-membrane domain Spore_YhaL PF14147.6 KKK12525.1 - 0.29 10.9 1.5 0.55 10.0 1.5 1.4 1 0 0 1 1 1 0 Sporulation protein YhaL Peroxidase_2 PF01328.17 KKK12526.1 - 6e-47 160.6 0.0 8.3e-47 160.1 0.0 1.2 1 0 0 1 1 1 1 Peroxidase, family 2 Ferric_reduct PF01794.19 KKK12527.1 - 1.6e-24 86.4 13.9 1.6e-24 86.4 13.9 1.7 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KKK12527.1 - 1.2e-15 57.9 0.0 1.9e-15 57.3 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KKK12527.1 - 3.1e-09 36.9 0.0 0.0058 16.7 0.0 2.9 3 0 0 3 3 3 2 FAD-binding domain NAD_binding_1 PF00175.21 KKK12527.1 - 0.00089 19.9 0.0 0.0063 17.1 0.0 2.1 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain FMO-like PF00743.19 KKK12528.1 - 8e-17 60.9 0.4 3.1e-15 55.6 0.0 2.8 2 2 1 3 3 3 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KKK12528.1 - 4.3e-13 49.2 0.0 2.2e-10 40.3 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KKK12528.1 - 4.8e-12 45.7 0.0 2.1e-11 43.7 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KKK12528.1 - 1.2e-10 41.1 0.0 1.3e-09 37.7 0.0 2.4 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KKK12528.1 - 1.1e-08 35.2 0.5 6.4e-07 29.5 0.0 3.1 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KKK12528.1 - 0.00016 20.9 1.2 0.003 16.7 0.0 2.5 3 0 0 3 3 3 1 Lycopene cyclase protein Pyr_redox PF00070.27 KKK12528.1 - 0.00065 20.2 0.3 2.6 8.7 0.2 2.8 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KKK12528.1 - 0.0022 17.1 0.0 0.0043 16.2 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 KKK12528.1 - 0.0041 16.4 0.4 0.015 14.5 0.1 2.0 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 KKK12528.1 - 0.0083 15.7 0.4 0.046 13.3 0.0 2.3 3 1 0 3 3 3 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KKK12528.1 - 0.0098 14.6 0.2 0.038 12.7 0.0 1.9 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_9 PF13454.6 KKK12528.1 - 0.052 13.5 1.4 4.9 7.1 0.0 3.4 3 1 0 3 3 3 0 FAD-NAD(P)-binding Cyt-b5 PF00173.28 KKK12529.1 - 3.3e-20 72.0 0.0 7.1e-20 70.9 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_M PF02770.19 KKK12529.1 - 7.5e-19 67.7 0.2 1.3e-18 66.9 0.2 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 KKK12529.1 - 9.4e-19 68.1 1.9 6.6e-18 65.3 1.9 2.1 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KKK12529.1 - 1.8e-06 28.6 0.3 7.3e-06 26.6 0.0 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain CBM-like PF14683.6 KKK12530.1 - 5.1e-27 94.8 0.2 1.7e-26 93.1 0.0 2.0 3 0 0 3 3 3 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.6 KKK12530.1 - 2.5e-23 81.7 0.6 7e-23 80.2 0.6 1.9 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain II CarboxypepD_reg PF13620.6 KKK12530.1 - 0.0025 18.1 0.2 0.011 16.0 0.2 2.2 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain DUF2012 PF09430.10 KKK12530.1 - 0.064 13.4 0.1 0.43 10.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2012) CarbopepD_reg_2 PF13715.6 KKK12530.1 - 0.076 13.0 0.3 6.4 6.9 0.0 2.6 2 0 0 2 2 2 0 CarboxypepD_reg-like domain Metallophos PF00149.28 KKK12531.1 - 5.7e-38 131.5 0.4 9.7e-38 130.7 0.4 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KKK12531.1 - 0.023 15.1 0.1 0.048 14.1 0.1 1.5 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain PI31_Prot_N PF11566.8 KKK12532.1 - 2.9e-51 173.5 0.0 3.6e-51 173.2 0.0 1.1 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.11 KKK12532.1 - 2.1e-17 64.0 17.2 2.1e-17 64.0 17.2 3.2 3 1 0 3 3 3 1 PI31 proteasome regulator HAD_2 PF13419.6 KKK12533.1 - 4.8e-16 59.3 0.0 7.7e-16 58.7 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KKK12533.1 - 9e-09 35.9 0.0 9.7e-08 32.5 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KKK12533.1 - 9.8e-05 22.3 0.0 0.00094 19.2 0.0 2.3 1 1 0 1 1 1 1 HAD-hyrolase-like NT5C PF06941.12 KKK12533.1 - 0.039 13.8 0.0 0.44 10.4 0.0 2.0 1 1 0 1 1 1 0 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) EBP PF05241.12 KKK12534.1 - 1.6e-65 219.9 8.8 1.9e-65 219.7 8.8 1.0 1 0 0 1 1 1 1 Emopamil binding protein TPR_1 PF00515.28 KKK12536.1 - 0.00047 19.9 6.8 0.095 12.6 0.0 4.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 KKK12536.1 - 0.00065 19.9 0.3 0.0019 18.4 0.3 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.6 KKK12536.1 - 0.023 14.7 0.1 4.9 7.4 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 KKK12536.1 - 0.031 14.4 5.2 5.4 7.4 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.6 KKK12536.1 - 0.06 13.8 0.3 0.56 10.7 0.2 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 KKK12536.1 - 0.12 12.1 0.7 0.41 10.4 0.7 2.0 1 0 0 1 1 1 0 TPR repeat TPR_19 PF14559.6 KKK12536.1 - 0.19 12.3 0.4 0.19 12.3 0.4 2.5 2 1 0 2 2 2 0 Tetratricopeptide repeat T6SS_VasJ PF16989.5 KKK12536.1 - 2.3 7.6 8.6 1.6 8.1 0.1 2.9 1 1 1 3 3 3 0 Type VI secretion, EvfE, EvfF, ImpA, BimE, VC_A0119, VasJ TPR_6 PF13174.6 KKK12536.1 - 4.6 8.1 5.2 25 5.8 0.0 3.4 3 1 0 3 3 3 0 Tetratricopeptide repeat GMC_oxred_N PF00732.19 KKK12537.1 - 4.9e-32 111.5 0.0 1.4e-28 100.1 0.0 2.4 2 1 0 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.13 KKK12537.1 - 1.1e-28 100.5 0.0 2.3e-28 99.5 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 KKK12537.1 - 0.00014 22.0 0.0 0.00039 20.6 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KKK12537.1 - 0.00018 20.9 0.0 0.28 10.4 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KKK12537.1 - 0.00023 20.5 0.0 0.00063 19.1 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KKK12537.1 - 0.0033 16.6 1.0 0.01 15.0 0.8 1.7 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 KKK12537.1 - 0.0052 15.9 0.0 0.0082 15.2 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein GIDA PF01134.22 KKK12537.1 - 0.017 14.3 0.2 0.52 9.3 0.1 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A HHH PF00633.23 KKK12537.1 - 0.03 14.2 0.6 4 7.5 0.0 3.0 3 0 0 3 3 3 0 Helix-hairpin-helix motif ApbA PF02558.16 KKK12537.1 - 0.033 13.8 0.2 0.069 12.8 0.2 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA HI0933_like PF03486.14 KKK12537.1 - 0.11 11.2 0.2 0.21 10.3 0.2 1.4 1 0 0 1 1 1 0 HI0933-like protein HHH_5 PF14520.6 KKK12537.1 - 0.14 12.8 0.1 3.7 8.2 0.1 2.7 1 1 0 1 1 1 0 Helix-hairpin-helix domain 3HCDH_N PF02737.18 KKK12537.1 - 0.2 11.5 0.0 0.52 10.2 0.0 1.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain CFEM PF05730.11 KKK12538.1 - 1.1e-15 57.5 13.9 2.6e-15 56.2 13.9 1.7 1 0 0 1 1 1 1 CFEM domain Rrp44_S1 PF17215.3 KKK12538.1 - 0.04 13.9 0.0 0.072 13.1 0.0 1.4 1 0 0 1 1 1 0 S1 domain Zn_clus PF00172.18 KKK12539.1 - 4.1e-09 36.4 9.6 7.8e-09 35.5 9.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KKK12539.1 - 0.0028 16.8 0.1 0.0086 15.1 0.1 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Phosphodiest PF01663.22 KKK12541.1 - 3.5e-28 99.2 0.0 5.5e-28 98.6 0.0 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase HD PF01966.22 KKK12541.1 - 8.7e-07 29.2 0.1 2e-06 28.0 0.1 1.6 1 0 0 1 1 1 1 HD domain HDOD PF08668.12 KKK12541.1 - 0.013 15.0 0.0 0.024 14.1 0.0 1.4 1 0 0 1 1 1 0 HDOD domain MIOX PF05153.15 KKK12541.1 - 0.05 13.2 0.0 0.08 12.5 0.0 1.2 1 0 0 1 1 1 0 Myo-inositol oxygenase PhyH PF05721.13 KKK12542.1 - 2.3e-29 103.2 0.1 2.3e-29 103.2 0.1 1.4 2 0 0 2 2 2 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.6 KKK12542.1 - 0.00025 21.4 0.0 0.00052 20.4 0.0 1.6 1 0 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase 2OG-FeII_Oxy_3 PF13640.6 KKK12542.1 - 0.031 15.2 0.0 0.059 14.3 0.0 1.5 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Crystall PF00030.19 KKK12542.1 - 0.04 14.1 0.0 0.54 10.5 0.0 2.2 2 0 0 2 2 2 0 Beta/Gamma crystallin Trehalase PF01204.18 KKK12544.1 - 6.4e-62 210.0 0.0 4.4e-42 144.6 0.2 3.0 1 1 0 2 2 2 2 Trehalase Trehalase_Ca-bi PF07492.11 KKK12544.1 - 2.2e-11 43.2 0.2 3.7e-11 42.5 0.2 1.4 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain GRDP-like PF07173.12 KKK12545.1 - 1.4e-20 74.4 1.9 4e-17 63.2 0.2 3.2 3 0 0 3 3 3 2 Glycine-rich domain-containing protein-like Sugar_tr PF00083.24 KKK12546.1 - 6.3e-28 97.8 23.2 1.1e-27 97.1 23.2 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKK12546.1 - 9e-14 51.2 31.2 9e-14 51.2 31.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Suc_Fer-like PF06999.12 KKK12547.1 - 3.7e-29 102.0 0.0 4.3e-29 101.8 0.0 1.0 1 0 0 1 1 1 1 Sucrase/ferredoxin-like zf-H2C2_2 PF13465.6 KKK12548.1 - 5.2e-16 58.3 21.1 1.4e-05 25.3 2.1 4.3 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.26 KKK12548.1 - 5.2e-14 51.8 30.1 3e-05 24.2 5.0 3.9 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KKK12548.1 - 6.8e-06 26.5 23.0 0.074 13.9 3.8 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_8 PF15909.5 KKK12548.1 - 0.013 15.8 7.2 0.34 11.2 1.1 2.9 1 1 0 2 2 2 0 C2H2-type zinc ribbon zf-C2H2_jaz PF12171.8 KKK12548.1 - 1.8 8.9 7.7 58 4.1 0.1 3.5 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding FAM183 PF14886.6 KKK12548.1 - 5 7.9 8.3 13 6.5 8.3 2.0 1 1 0 1 1 1 0 FAM183A and FAM183B related TFIIA PF03153.13 KKK12548.1 - 6.4 6.7 8.6 6.9 6.5 8.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Vps5 PF09325.10 KKK12550.1 - 1.9e-90 302.5 2.4 1.9e-90 302.5 2.4 1.4 2 0 0 2 2 2 1 Vps5 C terminal like PX PF00787.24 KKK12550.1 - 1.3e-25 89.6 0.2 2.8e-25 88.5 0.0 1.7 2 0 0 2 2 2 1 PX domain BAR_3 PF16746.5 KKK12550.1 - 0.063 13.0 9.7 2.8 7.6 4.6 2.8 1 1 1 2 2 2 0 BAR domain of APPL family DUF3450 PF11932.8 KKK12550.1 - 0.18 11.1 8.7 0.07 12.4 5.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Flavin_Reduct PF01613.18 KKK12552.1 - 1.8e-26 93.0 0.0 1.5e-20 73.8 0.1 2.4 2 0 0 2 2 2 2 Flavin reductase like domain Calreticulin PF00262.18 KKK12553.1 - 1.2e-166 554.1 14.7 1.2e-166 554.1 14.7 1.4 2 0 0 2 2 2 1 Calreticulin family DEC-1_C PF04626.13 KKK12554.1 - 0.035 14.5 0.4 0.12 12.8 0.4 1.9 1 0 0 1 1 1 0 Dec-1 protein, C terminal region Carbpep_Y_N PF05388.11 KKK12554.1 - 3.4 8.2 5.3 0.56 10.7 0.7 2.0 2 0 0 2 2 2 0 Carboxypeptidase Y pro-peptide Aldolase_II PF00596.21 KKK12555.1 - 3.1e-45 154.4 0.0 3.7e-45 154.1 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Complex1_LYR_2 PF13233.6 KKK12556.1 - 6.5e-19 68.5 0.0 8.2e-19 68.2 0.0 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 KKK12556.1 - 1.3e-09 38.0 0.0 2e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) RRM_1 PF00076.22 KKK12557.1 - 3.1e-11 42.9 0.1 8.2e-05 22.3 0.0 3.1 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4651 PF15513.6 KKK12557.1 - 0.032 14.1 0.0 3.5 7.5 0.0 3.0 3 1 0 3 3 3 0 Domain of unknown function (DUF4651) Tubulin PF00091.25 KKK12558.1 - 5e-68 229.2 0.0 1.1e-67 228.1 0.0 1.5 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KKK12558.1 - 1.4e-44 151.3 0.1 2.3e-44 150.6 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 KKK12558.1 - 4.5e-05 23.7 0.0 0.00012 22.4 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 KKK12558.1 - 0.0014 17.9 0.0 0.024 13.9 0.0 2.1 2 0 0 2 2 2 1 Tubulin like Tubulin_3 PF14881.6 KKK12558.1 - 0.0036 17.0 0.0 0.0065 16.2 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain TrmK PF04816.12 KKK12558.1 - 0.17 11.4 0.0 0.29 10.7 0.0 1.3 1 0 0 1 1 1 0 tRNA (adenine(22)-N(1))-methyltransferase Transp_cyt_pur PF02133.15 KKK12559.1 - 4.7e-14 52.0 36.5 9.6e-14 51.0 36.5 1.5 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Ammonium_transp PF00909.21 KKK12560.1 - 2e-105 352.8 29.0 4.4e-103 345.1 29.0 2.0 1 1 0 1 1 1 1 Ammonium Transporter Family SPDY PF03771.16 KKK12560.1 - 0.051 13.5 0.3 0.051 13.5 0.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF317) Transgly_assoc PF04226.13 KKK12560.1 - 0.27 11.5 0.2 0.27 11.5 0.2 5.3 6 0 0 6 6 6 0 Transglycosylase associated protein Phage_holin_2_1 PF04971.12 KKK12560.1 - 3.6 7.7 7.3 0.3 11.1 0.8 2.7 3 0 0 3 3 3 0 Bacteriophage P21 holin S PH PF00169.29 KKK12578.1 - 3.1e-07 30.9 0.0 4.5e-06 27.1 0.0 2.4 2 0 0 2 2 2 1 PH domain PH_9 PF15410.6 KKK12578.1 - 0.0032 17.8 0.0 0.01 16.2 0.0 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain Vps53_N PF04100.12 KKK12579.1 - 1e-110 370.3 4.0 1.1e-110 370.2 1.9 1.9 2 0 0 2 2 2 1 Vps53-like, N-terminal Vps54_N PF10475.9 KKK12579.1 - 1.6e-07 30.9 7.1 3e-07 30.0 7.1 1.3 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex DUF2451 PF10474.9 KKK12579.1 - 7.5e-07 29.2 1.0 1.8e-06 27.9 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function C-terminus (DUF2451) COG2 PF06148.11 KKK12579.1 - 2.5e-05 24.4 3.1 7.7e-05 22.8 2.4 2.3 2 0 0 2 2 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Spc7 PF08317.11 KKK12579.1 - 9.3e-05 21.4 6.7 0.00018 20.5 6.7 1.4 1 0 0 1 1 1 1 Spc7 kinetochore protein RINT1_TIP1 PF04437.13 KKK12579.1 - 0.00064 18.7 0.6 0.00064 18.7 0.6 3.0 2 1 0 2 2 2 1 RINT-1 / TIP-1 family Tnp_22_trimer PF17489.2 KKK12579.1 - 0.013 15.5 0.9 0.27 11.2 0.8 2.7 2 0 0 2 2 2 0 L1 transposable element trimerization domain Sec8_exocyst PF04048.14 KKK12579.1 - 0.015 15.2 2.1 0.015 15.2 2.1 1.9 2 0 0 2 2 1 0 Sec8 exocyst complex component specific domain COG5 PF10392.9 KKK12579.1 - 0.016 15.4 1.2 0.11 12.7 1.4 2.4 2 0 0 2 2 2 0 Golgi transport complex subunit 5 APG6_N PF17675.1 KKK12579.1 - 0.022 15.3 5.6 0.073 13.6 5.6 1.9 1 0 0 1 1 1 0 Apg6 coiled-coil region XhlA PF10779.9 KKK12579.1 - 0.028 14.6 4.7 0.048 13.9 3.1 2.3 2 0 0 2 2 2 0 Haemolysin XhlA Baculo_PEP_C PF04513.12 KKK12579.1 - 0.041 13.9 5.5 0.058 13.4 2.9 2.7 2 0 0 2 2 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus NBD94 PF16830.5 KKK12579.1 - 0.053 13.9 2.2 0.16 12.4 2.2 1.8 1 0 0 1 1 1 0 Nucleotide-Binding Domain 94 of RH Sigma70_ner PF04546.13 KKK12579.1 - 0.062 13.2 7.1 0.12 12.2 4.4 2.4 2 0 0 2 2 2 0 Sigma-70, non-essential region DUF5339 PF17274.2 KKK12579.1 - 0.11 13.4 3.6 3.4 8.6 1.3 3.2 2 1 1 3 3 2 0 Family of unknown function (DUF5339) YvfG PF09628.10 KKK12579.1 - 0.14 12.5 0.1 3.3 8.1 0.0 2.8 2 0 0 2 2 2 0 YvfG protein Syntaxin_2 PF14523.6 KKK12579.1 - 0.15 12.4 5.2 0.27 11.6 2.1 3.2 3 0 0 3 3 2 0 Syntaxin-like protein DUF1515 PF07439.11 KKK12579.1 - 0.16 12.0 2.2 0.48 10.5 2.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) DUF16 PF01519.16 KKK12579.1 - 0.2 12.2 2.8 1.3 9.6 2.4 2.5 2 0 0 2 2 2 0 Protein of unknown function DUF16 FapA PF03961.13 KKK12579.1 - 0.21 10.2 1.5 0.35 9.4 1.5 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF5082 PF16888.5 KKK12579.1 - 0.32 11.3 7.8 4 7.7 1.3 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF5082) Sec34 PF04136.15 KKK12579.1 - 0.33 10.8 5.7 1.1 9.2 4.4 2.5 2 1 0 2 2 2 0 Sec34-like family DUF1664 PF07889.12 KKK12579.1 - 0.89 9.6 5.3 1.2 9.2 2.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Atg14 PF10186.9 KKK12579.1 - 1.2 8.1 11.3 0.61 9.1 6.6 2.1 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Fez1 PF06818.15 KKK12579.1 - 1.3 9.5 6.9 3 8.2 6.9 1.6 1 0 0 1 1 1 0 Fez1 BRE1 PF08647.11 KKK12579.1 - 1.3 9.1 7.7 1.8 8.7 6.0 2.2 2 0 0 2 2 1 0 BRE1 E3 ubiquitin ligase BLOC1_2 PF10046.9 KKK12579.1 - 1.5 9.2 8.1 0.37 11.1 2.8 2.8 3 0 0 3 3 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Mod_r PF07200.13 KKK12579.1 - 1.8 8.7 8.6 0.92 9.6 4.7 2.5 2 1 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein TAP_C PF03943.13 KKK12580.1 - 5.8e-19 67.5 1.5 5.8e-19 67.5 1.5 1.9 2 0 0 2 2 2 1 TAP C-terminal domain NTF2 PF02136.20 KKK12580.1 - 1.3e-07 32.2 0.0 3.7e-07 30.7 0.0 1.8 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain LRR_9 PF14580.6 KKK12580.1 - 2.2e-06 27.3 0.0 3.7e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 KKK12580.1 - 2.8e-05 24.4 7.7 0.0015 18.9 1.0 2.6 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) RRM_9 PF18444.1 KKK12580.1 - 0.00016 21.5 0.0 0.00047 19.9 0.0 1.9 1 1 0 1 1 1 1 RNA recognition motif LRR_8 PF13855.6 KKK12580.1 - 0.00078 19.2 0.1 0.0019 18.0 0.1 1.7 1 0 0 1 1 1 1 Leucine rich repeat LRR_6 PF13516.6 KKK12580.1 - 0.013 15.5 1.1 7.2 6.9 0.2 3.3 3 0 0 3 3 3 0 Leucine Rich repeat LRR_1 PF00560.33 KKK12580.1 - 0.094 13.3 0.1 38 5.4 0.0 3.1 2 0 0 2 2 2 0 Leucine Rich Repeat AlgF PF11182.8 KKK12580.1 - 0.11 12.3 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 Alginate O-acetyl transferase AlgF COPIIcoated_ERV PF07970.12 KKK12581.1 - 1.8e-84 283.0 0.0 3.7e-84 282.0 0.0 1.5 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 KKK12581.1 - 9.1e-30 102.9 0.0 2.3e-29 101.6 0.0 1.7 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) DSPc PF00782.20 KKK12582.1 - 1.3e-07 31.5 0.0 1.9e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 KKK12582.1 - 0.016 15.5 0.0 0.024 15.0 0.0 1.3 1 0 0 1 1 1 0 Rit1 DUSP-like domain Aminotran_3 PF00202.21 KKK12583.1 - 3.8e-90 302.5 0.0 4.6e-90 302.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III EGF_alliinase PF04863.13 KKK12583.1 - 0.039 14.4 0.1 0.093 13.2 0.1 1.6 1 0 0 1 1 1 0 Alliinase EGF-like domain SNF2_N PF00176.23 KKK12585.1 - 3.2e-64 216.9 0.0 7.5e-64 215.7 0.0 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KKK12585.1 - 1.5e-21 76.8 0.7 1.1e-20 74.0 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KKK12585.1 - 1.1e-07 32.1 0.1 5.1e-07 29.9 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit TniB PF05621.11 KKK12585.1 - 0.038 13.4 0.1 4 6.8 0.1 2.5 2 0 0 2 2 2 0 Bacterial TniB protein Shugoshin_C PF07557.11 KKK12585.1 - 1.5 8.7 4.5 13 5.6 4.5 2.6 1 1 0 1 1 1 0 Shugoshin C terminus DDHD PF02862.17 KKK12585.1 - 8.6 6.4 9.9 2.7 8.1 2.0 2.8 2 1 0 2 2 2 0 DDHD domain Kinesin PF00225.23 KKK12586.1 - 1.4e-97 326.7 0.0 3.3e-97 325.4 0.0 1.7 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KKK12586.1 - 2.2e-22 79.6 0.0 5.6e-22 78.3 0.0 1.7 1 0 0 1 1 1 1 Microtubule binding Lebercilin PF15619.6 KKK12586.1 - 0.0049 16.6 2.2 0.0049 16.6 2.2 2.4 2 0 0 2 2 2 1 Ciliary protein causing Leber congenital amaurosis disease PKcGMP_CC PF16808.5 KKK12586.1 - 0.14 12.0 6.0 0.089 12.7 0.7 3.1 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF4407 PF14362.6 KKK12586.1 - 1.5 8.1 10.5 0.44 9.8 1.9 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Pkinase PF00069.25 KKK12587.1 - 4.4e-68 229.5 0.0 2.6e-66 223.7 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK12587.1 - 3.6e-34 118.2 0.0 2.2e-28 99.3 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase FHA PF00498.26 KKK12587.1 - 3.1e-14 53.1 0.0 6.8e-14 52.0 0.0 1.6 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.6 KKK12587.1 - 8.7e-08 31.8 0.2 0.0057 16.0 0.0 3.1 3 0 0 3 3 3 2 Kinase-like Yop-YscD_cpl PF16697.5 KKK12587.1 - 4e-05 23.8 0.0 9.5e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain APH PF01636.23 KKK12587.1 - 0.0021 18.0 0.2 0.018 15.0 0.2 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KKK12587.1 - 0.0023 16.8 1.6 0.007 15.2 0.1 2.3 2 1 0 2 2 2 1 Fungal protein kinase RIO1 PF01163.22 KKK12587.1 - 0.014 15.0 0.1 0.042 13.5 0.0 1.7 2 0 0 2 2 2 0 RIO1 family Pox_ser-thr_kin PF05445.11 KKK12587.1 - 0.043 12.8 0.1 0.063 12.2 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kdo PF06293.14 KKK12587.1 - 0.048 13.0 0.0 0.087 12.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KKK12587.1 - 0.066 12.1 1.2 0.072 12.0 0.0 1.6 2 0 0 2 2 2 0 Haspin like kinase domain FTA2 PF13095.6 KKK12587.1 - 0.073 12.7 0.0 2.1 7.9 0.0 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 YrbL-PhoP_reg PF10707.9 KKK12587.1 - 0.14 11.7 0.0 0.27 10.7 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL p450 PF00067.22 KKK12588.1 - 9.8e-77 258.6 0.0 1.1e-76 258.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 IGR PF09597.10 KKK12589.1 - 4e-25 87.7 0.4 9.3e-25 86.5 0.4 1.6 1 0 0 1 1 1 1 IGR protein motif SR-25 PF10500.9 KKK12589.1 - 0.0027 17.3 6.9 0.0027 17.3 6.9 1.8 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein Chorion_2 PF03964.15 KKK12589.1 - 0.0059 17.4 3.3 0.0096 16.7 3.3 1.4 1 0 0 1 1 1 1 Chorion family 2 Pkinase PF00069.25 KKK12590.1 - 2.5e-63 213.9 0.0 2.9e-63 213.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK12590.1 - 3.4e-33 115.0 0.0 5.4e-33 114.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KKK12590.1 - 0.098 12.0 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Kinase-like PI3_PI4_kinase PF00454.27 KKK12591.1 - 4.3e-39 134.8 0.0 2.2e-36 126.0 0.0 3.1 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 KKK12591.1 - 6.9e-25 87.5 0.2 1.5e-24 86.4 0.2 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) MCU PF04678.13 KKK12593.1 - 1.2e-25 90.6 0.1 1.2e-25 90.6 0.1 1.9 2 0 0 2 2 2 1 Mitochondrial calcium uniporter Sugar_tr PF00083.24 KKK12595.1 - 6.8e-95 318.6 18.7 9.4e-95 318.1 18.7 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKK12595.1 - 4.1e-26 91.7 27.0 3.8e-18 65.6 13.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Alpha-L-AF_C PF06964.12 KKK12596.1 - 4.4e-18 66.0 0.8 7.7e-18 65.2 0.8 1.4 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminal domain Glyco_hydro_79C PF16862.5 KKK12596.1 - 2.2 9.2 5.4 0.66 10.9 1.5 2.2 2 0 0 2 2 2 0 Glycosyl hydrolase family 79 C-terminal beta domain Neocarzinostat PF00960.18 KKK12596.1 - 4.2 7.4 11.7 13 5.8 0.0 3.5 3 0 0 3 3 3 0 Neocarzinostatin family Cutinase PF01083.22 KKK12597.1 - 2.2e-45 154.8 0.0 2.5e-45 154.6 0.0 1.0 1 0 0 1 1 1 1 Cutinase VirJ PF06057.11 KKK12597.1 - 6.1e-05 23.0 0.0 7.7e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Bacterial virulence protein (VirJ) PE-PPE PF08237.11 KKK12597.1 - 0.00098 18.7 0.0 0.0014 18.2 0.0 1.2 1 0 0 1 1 1 1 PE-PPE domain Glyco_transf_28 PF03033.20 KKK12597.1 - 0.092 12.8 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 28 N-terminal domain zf-C2H2 PF00096.26 KKK12599.1 - 0.00022 21.5 18.4 1.4 9.5 1.1 5.2 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KKK12599.1 - 0.0098 16.7 19.4 0.81 10.7 0.8 5.2 4 1 0 4 4 4 3 C2H2-type zinc finger zf-met PF12874.7 KKK12599.1 - 0.13 12.6 1.4 7.1 7.2 0.6 3.0 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KKK12599.1 - 0.64 10.4 6.2 5.4 7.4 0.6 3.3 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding ATP_transf PF09830.9 KKK12600.1 - 6.2e-23 80.7 0.0 1.1e-22 80.0 0.0 1.4 1 0 0 1 1 1 1 ATP adenylyltransferase GalP_UDP_transf PF01087.22 KKK12600.1 - 0.019 15.4 0.0 0.041 14.3 0.0 1.5 1 0 0 1 1 1 0 Galactose-1-phosphate uridyl transferase, N-terminal domain RACo_linker PF17650.1 KKK12600.1 - 0.13 12.1 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 RACo linker region GST_N_3 PF13417.6 KKK12601.1 - 1.6e-12 47.6 0.0 3e-12 46.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KKK12601.1 - 2.2e-11 43.9 0.0 4.5e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KKK12601.1 - 1.4e-06 28.5 0.1 3.9e-06 27.1 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KKK12601.1 - 4.8e-05 23.5 0.0 9.2e-05 22.6 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KKK12601.1 - 0.00023 21.3 0.0 0.00038 20.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KKK12601.1 - 0.008 16.2 0.2 0.018 15.1 0.1 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 KKK12601.1 - 0.033 14.8 0.0 0.32 11.6 0.0 2.1 1 1 1 2 2 2 0 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 KKK12601.1 - 0.048 14.4 0.0 0.17 12.7 0.0 2.0 1 1 0 1 1 1 0 Glutathione S-transferase N-terminal domain APH PF01636.23 KKK12602.1 - 1.4e-13 51.3 0.0 7.7e-13 48.9 0.0 2.2 1 1 0 1 1 1 1 Phosphotransferase enzyme family AA_permease_2 PF13520.6 KKK12604.1 - 1.6e-36 126.1 46.9 1.9e-36 125.8 46.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KKK12604.1 - 3.9e-15 55.4 38.0 5e-15 55.1 38.0 1.1 1 0 0 1 1 1 1 Amino acid permease Acetyltransf_3 PF13302.7 KKK12605.1 - 3e-13 50.6 0.0 4e-13 50.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KKK12605.1 - 5.6e-11 42.7 0.0 1e-10 41.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KKK12605.1 - 0.00012 22.4 0.0 0.00018 21.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KKK12605.1 - 0.0016 18.6 0.0 0.002 18.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 KKK12605.1 - 0.0023 17.7 0.0 0.0044 16.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KKK12605.1 - 0.0092 15.9 0.0 0.023 14.6 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KKK12605.1 - 0.13 12.3 0.1 0.39 10.7 0.1 1.8 1 1 0 1 1 1 0 FR47-like protein GMC_oxred_N PF00732.19 KKK12606.1 - 4.4e-79 265.9 0.0 6.4e-79 265.4 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KKK12606.1 - 1.1e-34 120.0 0.0 2.5e-34 118.9 0.0 1.6 1 1 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KKK12606.1 - 1.2e-06 27.9 0.3 0.016 14.3 0.2 2.2 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 KKK12606.1 - 6.7e-05 22.1 0.1 0.00011 21.4 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KKK12606.1 - 0.0019 17.5 0.1 0.0044 16.3 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KKK12606.1 - 0.0031 16.7 0.1 0.04 13.0 0.1 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A DAO PF01266.24 KKK12606.1 - 0.014 15.0 3.2 0.09 12.3 1.7 2.5 2 1 0 2 2 2 0 FAD dependent oxidoreductase Thi4 PF01946.17 KKK12606.1 - 0.019 14.2 0.3 0.11 11.7 0.1 1.9 2 0 0 2 2 2 0 Thi4 family FAD_oxidored PF12831.7 KKK12606.1 - 0.048 13.0 0.6 0.11 11.8 0.6 1.6 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KKK12606.1 - 0.053 13.8 0.4 0.13 12.5 0.4 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KKK12606.1 - 0.1 11.3 0.3 0.21 10.2 0.2 1.6 2 0 0 2 2 2 0 HI0933-like protein Trp_halogenase PF04820.14 KKK12606.1 - 0.15 10.8 0.1 0.25 10.2 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase GST_N_3 PF13417.6 KKK12607.1 - 3.7e-15 56.1 0.0 6.2e-15 55.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KKK12607.1 - 6.9e-15 55.1 0.0 1.2e-14 54.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KKK12607.1 - 4.6e-13 49.3 0.1 1.8e-12 47.4 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.24 KKK12607.1 - 0.00014 22.0 0.0 0.00022 21.4 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin Peptidase_S15 PF02129.18 KKK12608.1 - 4.8e-39 134.6 0.5 1.1e-36 126.8 0.1 2.1 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.10 KKK12608.1 - 1.4e-13 51.3 0.0 4.4e-13 49.7 0.0 1.7 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Hydrolase_4 PF12146.8 KKK12608.1 - 0.03 13.6 0.2 0.051 12.8 0.2 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Agglutinin PF07468.11 KKK12609.1 - 0.2 11.9 0.0 0.27 11.4 0.0 1.1 1 0 0 1 1 1 0 Agglutinin domain Abhydrolase_6 PF12697.7 KKK12610.1 - 1.6e-11 45.2 0.1 3.7e-11 44.0 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family DSBA PF01323.20 KKK12610.1 - 9.1e-11 41.9 0.0 1.3e-10 41.4 0.0 1.2 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Hydrolase_4 PF12146.8 KKK12610.1 - 2.1e-05 23.9 0.0 5.5e-05 22.5 0.0 1.7 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KKK12610.1 - 0.00017 21.4 0.2 0.00033 20.4 0.2 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF3613 PF12266.8 KKK12613.1 - 0.12 12.2 0.1 0.3 10.9 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3613) WD40 PF00400.32 KKK12614.1 - 2e-05 25.3 3.2 0.0012 19.6 0.0 3.9 4 0 0 4 4 4 2 WD domain, G-beta repeat 2-Hacid_dh_C PF02826.19 KKK12615.1 - 2.9e-39 134.3 0.1 5.1e-26 91.1 0.0 2.2 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 KKK12615.1 - 0.002 18.1 0.1 0.0033 17.3 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.17 KKK12615.1 - 0.16 12.6 0.0 0.35 11.5 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent EthD PF07110.11 KKK12616.1 - 0.0073 17.4 0.1 0.062 14.5 0.1 1.9 1 1 0 1 1 1 1 EthD domain PBP PF01161.20 KKK12617.1 - 3.3e-14 53.3 0.0 4.6e-14 52.9 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein FSH1 PF03959.13 KKK12618.1 - 4.6e-28 98.3 0.0 6e-28 98.0 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 KKK12618.1 - 0.0019 18.8 1.3 0.0035 18.0 1.3 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 KKK12618.1 - 0.011 15.6 0.1 0.093 12.5 0.0 2.1 2 1 0 2 2 2 0 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.13 KKK12618.1 - 0.18 11.6 0.1 1.1 9.0 0.0 2.0 2 0 0 2 2 2 0 alpha/beta hydrolase fold ketoacyl-synt PF00109.26 KKK12619.1 - 1.1e-50 172.6 0.0 6.1e-50 170.2 0.0 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 KKK12619.1 - 5.5e-37 126.4 0.6 1.1e-36 125.4 0.6 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.21 KKK12619.1 - 1.2e-25 90.7 0.8 1.3e-22 80.8 0.0 2.5 2 1 0 2 2 2 2 Acyl transferase domain SAT PF16073.5 KKK12619.1 - 9.9e-17 61.5 6.9 2.4e-14 53.7 0.1 4.1 2 1 1 3 3 3 1 Starter unit:ACP transacylase in aflatoxin biosynthesis KAsynt_C_assoc PF16197.5 KKK12619.1 - 1.2e-08 35.3 0.0 9.3e-08 32.5 0.0 2.4 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension PS-DH PF14765.6 KKK12619.1 - 4.3e-08 32.7 0.0 8.4e-08 31.8 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Thiolase_N PF00108.23 KKK12619.1 - 8.8e-06 25.3 0.3 2.1e-05 24.0 0.1 1.6 2 0 0 2 2 2 1 Thiolase, N-terminal domain ACP_syn_III PF08545.10 KKK12619.1 - 0.36 10.7 5.9 0.087 12.7 0.7 2.6 2 1 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Myosin_head PF00063.21 KKK12620.1 - 1.3e-241 803.5 3.5 1.7e-241 803.2 3.5 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 KKK12620.1 - 6.4e-53 179.2 0.0 1.5e-52 178.0 0.0 1.7 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding OPA3 PF07047.12 KKK12620.1 - 6.9e-47 158.3 1.9 1.7e-46 157.1 1.9 1.7 1 0 0 1 1 1 1 Optic atrophy 3 protein (OPA3) SH3_1 PF00018.28 KKK12620.1 - 3.2e-12 45.9 0.0 5.6e-12 45.1 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KKK12620.1 - 6.6e-08 32.1 0.0 1.6e-07 30.9 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 KKK12620.1 - 6.1e-06 26.0 0.0 1.4e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain AAA_16 PF13191.6 KKK12620.1 - 0.0078 16.6 0.5 0.17 12.2 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain IQ PF00612.27 KKK12620.1 - 0.0084 15.8 8.7 0.35 10.8 0.6 2.7 2 0 0 2 2 2 2 IQ calmodulin-binding motif Med11 PF10280.9 KKK12620.1 - 0.017 15.6 0.7 0.017 15.6 0.7 2.5 2 0 0 2 2 2 0 Mediator complex protein AAA_22 PF13401.6 KKK12620.1 - 0.023 15.0 0.0 0.074 13.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain Hpr_kinase_C PF07475.12 KKK12620.1 - 0.052 13.1 0.7 4.2 6.9 0.0 2.7 3 0 0 3 3 3 0 HPr Serine kinase C-terminal domain NACHT PF05729.12 KKK12620.1 - 0.18 11.7 0.0 0.58 10.1 0.0 1.9 2 0 0 2 2 2 0 NACHT domain Pkinase PF00069.25 KKK12621.1 - 2.1e-69 233.8 0.0 3.4e-69 233.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK12621.1 - 3.6e-45 154.3 0.0 5.5e-45 153.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.18 KKK12621.1 - 2.2e-09 37.4 0.3 0.0017 18.5 0.0 3.4 3 0 0 3 3 3 2 POLO box duplicated region Kinase-like PF14531.6 KKK12621.1 - 9.6e-07 28.4 0.0 1.9e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KKK12621.1 - 0.056 12.8 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Chitin_synth_2 PF03142.15 KKK12622.1 - 3.7e-284 943.2 0.1 5.3e-284 942.7 0.1 1.2 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.6 KKK12622.1 - 2.6e-09 37.3 7.0 1.6e-08 34.7 7.0 2.4 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KKK12622.1 - 1.1e-08 35.3 0.0 5.3e-07 29.8 0.0 2.7 2 1 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KKK12622.1 - 4e-05 23.5 0.0 0.018 14.9 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 KKK12622.1 - 0.0015 18.1 0.0 0.0083 15.6 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase family 21 Sel1 PF08238.12 KKK12623.1 - 3.1e-40 135.7 27.5 2.8e-06 27.8 0.2 7.5 7 0 0 7 7 7 7 Sel1 repeat HTH_23 PF13384.6 KKK12623.1 - 0.14 12.0 0.2 0.31 10.9 0.2 1.6 1 0 0 1 1 1 0 Homeodomain-like domain TPR_6 PF13174.6 KKK12623.1 - 0.19 12.4 8.4 20 6.1 0.1 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.6 KKK12623.1 - 0.46 11.0 8.9 0.67 10.5 0.2 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF3112 PF11309.8 KKK12624.1 - 4.6e-14 52.4 5.3 1.4e-09 37.8 1.2 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF3112) DUF4407 PF14362.6 KKK12624.1 - 0.061 12.7 1.4 0.11 11.9 1.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF996 PF06195.13 KKK12624.1 - 3.3 8.0 14.8 2 8.7 6.5 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF996) HTH_51 PF18558.1 KKK12625.1 - 8.5e-28 96.1 0.0 2.9e-27 94.4 0.0 1.9 1 0 0 1 1 1 1 Helix-turn-helix domain Methyltransf_23 PF13489.6 KKK12625.1 - 4.1e-16 59.2 0.1 1e-15 58.0 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KKK12625.1 - 2.1e-15 57.2 0.0 6e-15 55.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.25 KKK12625.1 - 1.7e-13 50.7 1.0 3.3e-13 49.8 1.0 1.5 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_25 PF13649.6 KKK12625.1 - 9.3e-13 48.7 0.0 4e-12 46.7 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KKK12625.1 - 2.2e-10 41.0 0.4 2e-09 37.9 0.0 2.5 3 0 0 3 3 2 1 Methyltransferase domain PS-DH PF14765.6 KKK12625.1 - 1.6e-09 37.4 0.0 2.1e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase Methyltransf_31 PF13847.6 KKK12625.1 - 2.8e-06 27.2 0.0 6.2e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KKK12625.1 - 0.0011 18.3 0.0 0.0047 16.3 0.0 1.9 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_28 PF02636.17 KKK12625.1 - 0.0031 17.2 0.0 0.0051 16.5 0.0 1.3 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_24 PF13578.6 KKK12625.1 - 0.054 14.5 0.1 8.5 7.5 0.0 3.8 4 1 0 4 4 4 0 Methyltransferase domain Methyltransf_33 PF10017.9 KKK12625.1 - 0.092 11.9 0.0 0.18 10.9 0.0 1.4 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent SURF4 PF02077.15 KKK12627.1 - 4e-94 315.2 8.5 4.5e-94 315.0 8.5 1.0 1 0 0 1 1 1 1 SURF4 family UPF0139 PF03669.13 KKK12627.1 - 0.28 11.1 1.4 1.3 9.0 1.1 2.2 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0139) DJ-1_PfpI PF01965.24 KKK12647.1 - 2.8e-07 30.5 0.0 6.5e-07 29.3 0.0 1.8 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 KKK12647.1 - 0.0043 16.8 0.0 0.013 15.2 0.0 1.8 1 1 0 1 1 1 1 ThiJ/PfpI family-like CBM_1 PF00734.18 KKK12648.1 - 2.2e-10 40.3 15.0 2.2e-10 40.3 15.0 2.3 2 0 0 2 2 2 1 Fungal cellulose binding domain BNR PF02012.20 KKK12648.1 - 3.7e-07 29.2 44.0 0.23 11.6 0.1 9.8 9 0 0 9 9 9 6 BNR/Asp-box repeat BNR_6 PF15899.5 KKK12648.1 - 0.0042 17.0 15.5 7 7.0 0.1 7.3 8 0 0 8 8 8 3 BNR-Asp box repeat BNR_2 PF13088.6 KKK12648.1 - 0.041 13.2 0.2 0.041 13.2 0.2 5.6 4 2 2 6 6 6 0 BNR repeat-like domain TEX19 PF15553.6 KKK12648.1 - 0.11 12.5 0.1 0.25 11.3 0.1 1.5 1 0 0 1 1 1 0 Testis-expressed protein 19 DUF2452 PF10504.9 KKK12648.1 - 0.18 11.3 0.0 0.32 10.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2452) p450 PF00067.22 KKK12649.1 - 4.2e-54 184.0 0.2 5.9e-54 183.5 0.2 1.1 1 0 0 1 1 1 1 Cytochrome P450 DPBB_1 PF03330.18 KKK12650.1 - 2.3e-08 34.2 0.2 3.2e-08 33.7 0.2 1.2 1 0 0 1 1 1 1 Lytic transglycolase CRAL_TRIO PF00650.20 KKK12651.1 - 1.9e-37 128.5 0.0 3.1e-37 127.7 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 KKK12651.1 - 2.5e-06 27.7 0.0 4.2e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KKK12651.1 - 0.0033 17.6 0.0 0.01 16.0 0.0 1.9 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain NYD-SP28 PF14772.6 KKK12651.1 - 0.19 11.8 1.4 0.35 10.9 1.4 1.4 1 0 0 1 1 1 0 Sperm tail Trp_DMAT PF11991.8 KKK12652.1 - 1.9e-94 317.1 0.0 2.2e-94 316.9 0.0 1.1 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase ABC_tran PF00005.27 KKK12653.1 - 2e-52 177.4 0.0 4.7e-30 104.9 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KKK12653.1 - 1.4e-37 129.9 15.2 8.2e-24 84.7 7.1 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 KKK12653.1 - 1.9e-08 34.1 0.0 0.0016 17.9 0.1 3.7 3 2 0 4 4 3 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 KKK12653.1 - 4.2e-06 26.8 0.2 0.017 15.0 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 KKK12653.1 - 1.1e-05 25.5 0.0 0.021 14.9 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_23 PF13476.6 KKK12653.1 - 4.6e-05 24.0 0.2 0.033 14.7 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KKK12653.1 - 0.00014 22.1 1.9 0.31 11.3 0.1 3.3 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KKK12653.1 - 0.00016 22.1 0.5 0.84 10.0 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.6 KKK12653.1 - 0.0012 18.4 0.6 1.5 8.3 0.2 2.9 2 1 1 3 3 3 2 AAA domain TsaE PF02367.17 KKK12653.1 - 0.0023 17.9 0.0 0.12 12.3 0.0 2.6 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zeta_toxin PF06414.12 KKK12653.1 - 0.0028 16.9 0.2 0.72 9.1 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin AAA_29 PF13555.6 KKK12653.1 - 0.004 16.9 0.4 2.7 7.8 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain CbiA PF01656.23 KKK12653.1 - 0.0047 17.0 0.0 1.1 9.3 0.0 3.0 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_30 PF13604.6 KKK12653.1 - 0.0064 16.2 0.0 0.36 10.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 KKK12653.1 - 0.0066 16.2 0.0 0.11 12.2 0.0 2.6 2 0 0 2 2 2 1 IstB-like ATP binding protein cobW PF02492.19 KKK12653.1 - 0.0075 15.9 0.5 0.29 10.7 0.1 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 KKK12653.1 - 0.008 16.1 1.0 1 9.3 0.1 2.5 2 0 0 2 2 2 1 NACHT domain MobB PF03205.14 KKK12653.1 - 0.015 15.2 0.7 3.6 7.5 0.1 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA PF00004.29 KKK12653.1 - 0.02 15.3 0.2 9.9 6.6 0.0 3.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_21 PF13304.6 KKK12653.1 - 0.037 13.8 6.3 33 4.1 0.0 5.0 4 1 0 5 5 5 0 AAA domain, putative AbiEii toxin, Type IV TA system RNA_helicase PF00910.22 KKK12653.1 - 0.039 14.3 0.0 11 6.5 0.0 2.9 3 0 0 3 3 2 0 RNA helicase ATPase PF06745.13 KKK12653.1 - 0.044 13.1 0.0 2.4 7.4 0.0 2.5 2 0 0 2 2 2 0 KaiC AAA_7 PF12775.7 KKK12653.1 - 0.044 13.3 0.0 1.7 8.1 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region FtsK_SpoIIIE PF01580.18 KKK12653.1 - 0.048 13.0 0.2 8.2 5.7 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family DUF2075 PF09848.9 KKK12653.1 - 0.055 12.7 0.4 0.68 9.1 0.1 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) NB-ARC PF00931.22 KKK12653.1 - 0.068 12.3 0.2 42 3.2 0.1 3.2 3 0 0 3 3 3 0 NB-ARC domain ATP-synt_ab PF00006.25 KKK12653.1 - 0.07 12.8 0.0 4 7.0 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain DnaB_C PF03796.15 KKK12653.1 - 0.08 12.3 0.0 1.5 8.1 0.0 2.5 3 0 0 3 3 3 0 DnaB-like helicase C terminal domain T2SSE PF00437.20 KKK12653.1 - 0.12 11.4 0.0 6.3 5.8 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein APS_kinase PF01583.20 KKK12653.1 - 0.13 12.1 0.5 0.29 11.0 0.0 1.8 2 0 0 2 2 2 0 Adenylylsulphate kinase DUF87 PF01935.17 KKK12653.1 - 0.13 12.3 5.6 0.14 12.2 0.2 3.0 3 0 0 3 3 3 0 Helicase HerA, central domain AAA_33 PF13671.6 KKK12653.1 - 0.15 12.2 0.1 20 5.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain Adeno_IVa2 PF02456.15 KKK12653.1 - 0.88 8.3 2.2 4 6.1 0.0 2.9 4 0 0 4 4 4 0 Adenovirus IVa2 protein MFS_1 PF07690.16 KKK12654.1 - 6.7e-14 51.6 12.8 1.2e-13 50.8 12.8 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily p450 PF00067.22 KKK12655.1 - 1.7e-62 211.7 0.0 2.2e-62 211.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 PALP PF00291.25 KKK12656.1 - 2.8e-30 105.8 0.0 1.7e-18 67.0 0.0 2.0 1 1 1 2 2 2 2 Pyridoxal-phosphate dependent enzyme Git3 PF11710.8 KKK12657.1 - 6.8e-25 88.0 8.7 6.8e-25 88.0 8.7 1.7 2 1 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 GPR_Gpa2_C PF11970.8 KKK12657.1 - 1.5e-08 34.6 2.2 1.8e-08 34.4 0.1 2.2 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 C-term 7tm_1 PF00001.21 KKK12657.1 - 0.0041 16.5 3.0 0.0041 16.5 3.0 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF3215 PF11503.8 KKK12657.1 - 0.013 15.4 0.1 0.026 14.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3215) Nterm_IS4 PF13006.7 KKK12657.1 - 0.1 12.8 0.1 0.3 11.3 0.1 1.7 1 0 0 1 1 1 0 Insertion element 4 transposase N-terminal Con-6 PF10346.9 KKK12658.1 - 1.6e-32 111.2 12.0 8.4e-14 51.3 0.2 3.7 4 0 0 4 4 4 3 Conidiation protein 6 IncFII_repA PF02387.15 KKK12658.1 - 0.084 12.1 0.3 2.7 7.2 0.0 2.2 2 0 0 2 2 2 0 IncFII RepA protein family DUF1771 PF08590.10 KKK12658.1 - 0.58 10.6 7.3 9.2 6.7 0.1 3.6 3 1 0 3 3 3 0 Domain of unknown function (DUF1771) Sugar_tr PF00083.24 KKK12659.1 - 5.8e-127 424.3 25.6 6.6e-127 424.1 25.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKK12659.1 - 3.7e-23 82.0 72.8 2.5e-21 76.0 39.7 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily GRDP-like PF07173.12 KKK12661.1 - 6.3e-19 69.0 0.1 1e-13 52.2 0.0 2.6 2 0 0 2 2 2 2 Glycine-rich domain-containing protein-like Glyco_hydro_16 PF00722.21 KKK12662.1 - 8e-39 132.9 2.6 1.2e-38 132.3 2.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Laminin_G_3 PF13385.6 KKK12662.1 - 0.014 15.5 0.8 0.026 14.7 0.8 1.5 1 0 0 1 1 1 0 Concanavalin A-like lectin/glucanases superfamily ERG2_Sigma1R PF04622.12 KKK12662.1 - 0.079 12.3 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 ERG2 and Sigma1 receptor like protein HsbA PF12296.8 KKK12663.1 - 2.6e-22 79.5 16.5 2.6e-22 79.5 16.5 3.7 2 1 1 3 3 3 1 Hydrophobic surface binding protein A FPP PF05911.11 KKK12663.1 - 4.5 5.3 6.7 5.5 5.0 6.7 1.2 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil Aha1_N PF09229.11 KKK12664.1 - 3.3e-42 144.0 0.6 6.1e-42 143.1 0.6 1.5 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.11 KKK12664.1 - 2.9e-20 72.7 0.3 5.2e-20 71.9 0.3 1.4 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein FBPase PF00316.20 KKK12666.1 - 1.8e-69 233.1 0.2 2.3e-69 232.7 0.2 1.1 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain rRNA_processing PF08524.11 KKK12687.1 - 6.6 6.7 21.0 0.93 9.5 14.9 2.3 2 1 0 2 2 2 0 rRNA processing Eaf7 PF07904.13 KKK12688.1 - 7.6e-29 100.2 4.0 9.5e-29 99.9 0.0 2.2 2 0 0 2 2 2 1 Chromatin modification-related protein EAF7 Nop14 PF04147.12 KKK12688.1 - 0.017 13.4 14.5 0.021 13.1 14.5 1.1 1 0 0 1 1 1 0 Nop14-like family RNA_pol_3_Rpc31 PF11705.8 KKK12688.1 - 0.033 14.4 17.9 0.062 13.6 17.9 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Cwf_Cwc_15 PF04889.12 KKK12688.1 - 0.062 13.0 15.7 0.096 12.4 15.7 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein SDA1 PF05285.12 KKK12688.1 - 0.29 10.5 15.8 0.4 10.1 15.8 1.2 1 0 0 1 1 1 0 SDA1 PPP4R2 PF09184.11 KKK12688.1 - 0.35 10.4 10.8 0.55 9.8 10.8 1.4 1 0 0 1 1 1 0 PPP4R2 NOA36 PF06524.12 KKK12688.1 - 0.4 9.9 14.6 0.66 9.2 14.6 1.3 1 0 0 1 1 1 0 NOA36 protein Mpp10 PF04006.12 KKK12688.1 - 2.7 6.3 16.4 4.1 5.7 16.4 1.2 1 0 0 1 1 1 0 Mpp10 protein SAPS PF04499.15 KKK12688.1 - 2.8 6.6 4.2 3.1 6.5 4.2 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Nop53 PF07767.11 KKK12688.1 - 3.6 6.9 18.3 0.86 8.9 14.6 1.7 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) DNA_pol_phi PF04931.13 KKK12688.1 - 4 5.4 27.2 5.4 5.0 27.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi SpoIIIAH PF12685.7 KKK12688.1 - 5.2 6.8 7.9 7 6.4 7.9 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein TFB6 PF17110.5 KKK12688.1 - 7.2 6.3 6.8 13 5.5 6.8 1.4 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Ribosomal_L5e PF17144.4 KKK12689.1 - 2e-81 271.8 0.3 3.9e-81 270.8 0.3 1.5 1 0 0 1 1 1 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 KKK12689.1 - 5e-34 117.1 8.6 5e-34 117.1 8.6 2.1 3 0 0 3 3 3 1 Ribosomal L18 C-terminal region HAD_2 PF13419.6 KKK12689.1 - 0.0074 16.4 0.0 0.023 14.8 0.0 1.9 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase FTA4 PF13093.6 KKK12690.1 - 4.5e-62 209.5 12.2 5.2e-62 209.3 12.2 1.0 1 0 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 CHDCT2 PF08074.11 KKK12690.1 - 0.014 15.6 0.5 0.014 15.6 0.5 2.0 1 1 1 2 2 2 0 CHDCT2 (NUC038) domain PAP_central PF04928.17 KKK12690.1 - 1.4 7.9 4.3 0.64 9.0 1.1 1.8 1 1 1 2 2 2 0 Poly(A) polymerase central domain Wtap PF17098.5 KKK12691.1 - 0.0037 17.2 0.3 0.036 14.0 0.3 2.3 2 0 0 2 2 2 1 WTAP/Mum2p family SlyX PF04102.12 KKK12691.1 - 0.0078 16.8 0.7 0.067 13.8 0.1 2.7 3 0 0 3 3 3 1 SlyX GlutR_dimer PF00745.20 KKK12691.1 - 0.032 14.7 1.0 0.11 12.9 0.4 2.3 2 1 0 2 2 2 0 Glutamyl-tRNAGlu reductase, dimerisation domain CENP-H PF05837.12 KKK12691.1 - 0.055 13.9 1.5 0.13 12.6 1.5 1.6 1 0 0 1 1 1 0 Centromere protein H (CENP-H) SIKE PF05769.11 KKK12691.1 - 0.31 10.9 7.1 0.41 10.5 7.1 1.1 1 0 0 1 1 1 0 SIKE family MFS_1 PF07690.16 KKK12692.1 - 3.9e-28 98.4 19.5 4.9e-28 98.1 19.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily rhaM PF05336.13 KKK12692.1 - 2.4e-15 56.5 0.1 4.1e-15 55.8 0.1 1.3 1 0 0 1 1 1 1 L-rhamnose mutarotase Pox_A14 PF05767.12 KKK12692.1 - 0.075 13.2 0.0 0.23 11.7 0.0 1.8 1 0 0 1 1 1 0 Poxvirus virion envelope protein A14 Thiolase_N PF00108.23 KKK12694.1 - 6.7e-71 238.7 0.2 1.1e-70 238.0 0.2 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KKK12694.1 - 7e-40 135.5 0.4 7e-40 135.5 0.4 1.8 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KKK12694.1 - 0.00085 19.0 1.5 0.0054 16.3 1.2 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 KKK12694.1 - 0.02 14.7 0.1 1 9.3 0.0 2.7 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III RhoGAP PF00620.27 KKK12695.1 - 3.9e-48 163.1 0.3 1.1e-47 161.7 0.0 1.9 2 0 0 2 2 2 1 RhoGAP domain LIM PF00412.22 KKK12695.1 - 1.3e-13 51.0 20.7 4.8e-09 36.3 4.3 2.5 2 0 0 2 2 2 2 LIM domain Fez1 PF06818.15 KKK12695.1 - 0.034 14.6 16.1 0.047 14.1 12.0 2.6 1 1 1 2 2 2 0 Fez1 AAA_23 PF13476.6 KKK12695.1 - 0.077 13.5 3.8 0.18 12.2 3.8 1.6 1 0 0 1 1 1 0 AAA domain DUF536 PF04394.14 KKK12695.1 - 0.64 9.9 3.9 4 7.4 1.3 2.6 2 0 0 2 2 2 0 Protein of unknown function, DUF536 CENP-H PF05837.12 KKK12695.1 - 1.3 9.4 12.4 0.31 11.4 2.0 3.4 2 1 1 3 3 3 0 Centromere protein H (CENP-H) TF_Zn_Ribbon PF08271.12 KKK12695.1 - 3.6 7.2 18.8 1.8 8.1 1.1 5.1 4 1 1 5 5 5 0 TFIIB zinc-binding DASH_Ask1 PF08655.10 KKK12696.1 - 7.7e-31 105.8 0.1 1.5e-30 104.9 0.1 1.5 1 0 0 1 1 1 1 DASH complex subunit Ask1 PBP1_TM PF14812.6 KKK12696.1 - 1.3 9.5 19.0 0.28 11.6 5.4 3.4 2 1 1 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal BSP PF04450.12 KKK12697.1 - 5.1e-72 242.0 0.0 7.1e-72 241.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase of plants and bacteria Peptidase_M91 PF14891.6 KKK12697.1 - 0.15 12.3 0.0 0.19 12.0 0.0 1.3 1 0 0 1 1 1 0 Effector protein CLASP_N PF12348.8 KKK12698.1 - 4.3e-154 510.6 2.0 1.2e-87 293.3 0.0 2.2 2 0 0 2 2 2 2 CLASP N terminal HEAT PF02985.22 KKK12698.1 - 2.5e-10 39.7 0.0 0.014 15.6 0.0 5.8 5 0 0 5 5 5 2 HEAT repeat Cnd1 PF12717.7 KKK12698.1 - 3.4e-06 27.2 0.2 0.071 13.2 0.0 3.8 3 1 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KKK12698.1 - 3.6e-05 24.1 0.8 1.2 9.6 0.1 3.8 3 0 0 3 3 3 2 HEAT repeats HEAT_EZ PF13513.6 KKK12698.1 - 0.0011 19.5 0.1 1.3 9.6 0.0 3.5 3 0 0 3 3 3 1 HEAT-like repeat Adaptin_N PF01602.20 KKK12698.1 - 0.038 12.6 0.1 0.59 8.6 0.1 2.4 1 1 1 2 2 2 0 Adaptin N terminal region Condensin2nSMC PF12422.8 KKK12698.1 - 0.082 13.1 0.2 3.9 7.6 0.1 2.9 3 0 0 3 3 3 0 Condensin II non structural maintenance of chromosomes subunit DUF3361 PF11841.8 KKK12698.1 - 0.086 12.8 0.4 0.27 11.2 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3361) Ribonuclease_3 PF00636.26 KKK12700.1 - 2.6e-08 34.4 0.0 7.6e-08 32.9 0.0 1.8 1 1 0 1 1 1 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 KKK12700.1 - 1.1e-07 32.0 0.0 0.00077 19.6 0.0 2.3 2 0 0 2 2 2 2 Ribonuclease-III-like dsrm PF00035.26 KKK12700.1 - 5e-07 30.3 0.0 1.1e-06 29.2 0.0 1.6 1 0 0 1 1 1 1 Double-stranded RNA binding motif DUF4210 PF13915.6 KKK12701.1 - 7.1e-31 106.6 0.1 2e-30 105.1 0.1 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4210) Chromosome_seg PF13889.6 KKK12701.1 - 7.1e-24 83.7 0.4 1.5e-23 82.7 0.4 1.6 1 0 0 1 1 1 1 Chromosome segregation during meiosis Sec5 PF15469.6 KKK12702.1 - 1.1e-35 123.2 0.0 2.6e-35 121.9 0.0 1.7 1 0 0 1 1 1 1 Exocyst complex component Sec5 Vps51 PF08700.11 KKK12702.1 - 1.1e-05 25.4 0.2 4.7e-05 23.4 0.2 2.1 1 0 0 1 1 1 1 Vps51/Vps67 DUF3979 PF13141.6 KKK12702.1 - 0.067 13.5 0.0 0.19 12.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3979) Iso_dh PF00180.20 KKK12703.1 - 9.3e-89 298.0 0.0 2.2e-57 194.8 0.0 2.0 1 1 1 2 2 2 2 Isocitrate/isopropylmalate dehydrogenase HHH_2 PF12826.7 KKK12703.1 - 0.0051 16.9 0.1 0.087 12.9 0.0 2.3 2 0 0 2 2 2 1 Helix-hairpin-helix motif GCP_C_terminal PF04130.13 KKK12704.1 - 1.2e-70 238.4 0.0 2.2e-70 237.6 0.0 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 KKK12704.1 - 3e-54 184.7 1.0 5.2e-54 183.9 1.0 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal DOG1 PF14144.6 KKK12704.1 - 0.02 15.1 0.0 0.057 13.6 0.0 1.8 1 0 0 1 1 1 0 Seed dormancy control Mo-co_dimer PF03404.16 KKK12705.1 - 9.6e-60 200.6 0.0 1.7e-59 199.8 0.0 1.4 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Oxidored_molyb PF00174.19 KKK12705.1 - 1.8e-50 170.9 0.0 3.3e-50 170.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain FAD_binding_6 PF00970.24 KKK12705.1 - 4.5e-33 113.5 0.0 8.1e-33 112.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 KKK12705.1 - 5.2e-31 107.5 0.0 1.1e-30 106.4 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Cyt-b5 PF00173.28 KKK12705.1 - 6.9e-13 48.6 0.0 1.6e-12 47.4 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.12 KKK12705.1 - 2.9e-05 24.2 1.6 0.037 14.2 0.0 3.0 2 1 1 3 3 3 2 Ferric reductase NAD binding domain Secretin_N_2 PF07655.13 KKK12705.1 - 0.019 15.5 4.5 0.039 14.5 4.5 1.4 1 0 0 1 1 1 0 Secretin N-terminal domain SSP160 PF06933.11 KKK12705.1 - 3.8 5.6 9.8 5.4 5.1 9.8 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 PfkB PF00294.24 KKK12706.1 - 6.3e-13 48.7 0.0 2.7e-12 46.6 0.0 1.9 1 1 0 1 1 1 1 pfkB family carbohydrate kinase CAP_N PF01213.19 KKK12707.1 - 1.6e-112 376.1 8.3 8.5e-112 373.7 8.3 2.0 1 1 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.11 KKK12707.1 - 7.2e-47 158.9 2.3 1.2e-46 158.2 2.3 1.3 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.12 KKK12707.1 - 0.021 14.5 3.5 2.1 8.1 3.9 2.2 1 1 1 2 2 2 0 Tubulin binding cofactor C Pyr_redox_2 PF07992.14 KKK12708.1 - 4e-45 154.3 0.1 7.1e-45 153.5 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NIR_SIR PF01077.22 KKK12708.1 - 3.1e-20 72.3 0.0 7.3e-20 71.1 0.0 1.7 1 0 0 1 1 1 1 Nitrite and sulphite reductase 4Fe-4S domain Pyr_redox PF00070.27 KKK12708.1 - 1.8e-18 66.9 1.9 2.7e-17 63.1 0.3 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Fer2_BFD PF04324.15 KKK12708.1 - 3.7e-16 59.2 7.7 5.9e-13 49.0 5.3 2.9 2 0 0 2 2 2 2 BFD-like [2Fe-2S] binding domain Rieske_2 PF13806.6 KKK12708.1 - 1.7e-14 53.6 0.0 4e-14 52.4 0.0 1.7 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Rieske PF00355.26 KKK12708.1 - 6.7e-14 51.6 0.1 4e-13 49.1 0.0 2.3 2 0 0 2 2 2 1 Rieske [2Fe-2S] domain NIR_SIR_ferr PF03460.17 KKK12708.1 - 9.2e-12 44.6 0.0 2.1e-11 43.5 0.0 1.7 1 0 0 1 1 1 1 Nitrite/Sulfite reductase ferredoxin-like half domain Rubredoxin_C PF18267.1 KKK12708.1 - 3.6e-06 26.8 0.3 0.041 13.8 0.1 3.5 3 0 0 3 3 3 2 Rubredoxin NAD+ reductase C-terminal domain NAD_binding_9 PF13454.6 KKK12708.1 - 0.0039 17.2 0.5 6.4 6.8 0.0 3.7 3 1 1 4 4 4 1 FAD-NAD(P)-binding HI0933_like PF03486.14 KKK12708.1 - 0.014 14.1 0.0 1.2 7.8 0.0 2.5 3 0 0 3 3 3 0 HI0933-like protein adh_short PF00106.25 KKK12709.1 - 4.2e-09 36.1 0.0 0.0016 17.9 0.0 3.0 2 1 0 2 2 2 2 short chain dehydrogenase SBD_N PF07005.11 KKK12710.1 - 8.9e-41 140.1 1.5 3.3e-31 108.8 0.1 2.5 3 0 0 3 3 3 2 Sugar-binding N-terminal domain NBD_C PF17042.5 KKK12710.1 - 8.3e-40 137.1 1.7 1.5e-39 136.2 1.7 1.4 1 0 0 1 1 1 1 Nucleotide-binding C-terminal domain WD40 PF00400.32 KKK12712.1 - 2.9e-28 97.5 6.6 1.3e-06 29.0 0.0 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKK12712.1 - 2.3e-13 50.3 0.0 0.0004 20.6 0.0 4.8 3 2 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KKK12712.1 - 0.0006 19.8 0.1 0.31 10.9 0.0 2.9 2 1 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A ABC2_membrane PF01061.24 KKK12713.1 - 2.6e-38 131.6 20.6 4.7e-38 130.7 20.6 1.5 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 KKK12713.1 - 4.9e-25 88.6 0.0 9e-25 87.8 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KKK12713.1 - 3.6e-05 23.7 0.0 0.3 10.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 KKK12713.1 - 0.00025 20.3 16.8 0.00025 20.3 16.8 2.2 1 1 0 2 2 2 1 ABC-2 family transporter protein AAA_16 PF13191.6 KKK12713.1 - 0.0085 16.5 0.0 0.018 15.4 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 KKK12713.1 - 0.0094 15.7 0.1 0.021 14.6 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KKK12713.1 - 0.011 15.7 0.0 0.019 14.8 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_18 PF13238.6 KKK12713.1 - 0.022 15.3 0.0 0.054 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KKK12713.1 - 0.022 15.0 0.0 0.055 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 KKK12713.1 - 0.05 14.1 0.0 0.14 12.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KKK12713.1 - 0.073 13.0 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_33 PF13671.6 KKK12713.1 - 0.084 13.0 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.19 KKK12713.1 - 0.096 12.1 0.0 2.1 7.7 0.0 2.2 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain ATPase_2 PF01637.18 KKK12713.1 - 0.1 12.5 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_14 PF13173.6 KKK12713.1 - 0.12 12.4 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KKK12713.1 - 0.17 11.4 1.0 0.32 10.5 0.1 1.9 2 0 0 2 2 2 0 AAA domain Spem1 PF15670.5 KKK12713.1 - 0.41 10.2 4.2 0.69 9.4 4.2 1.2 1 0 0 1 1 1 0 Spermatid maturation protein 1 Laminin_EGF PF00053.24 KKK12713.1 - 1.2 9.4 28.7 0.6 10.3 7.9 3.7 2 1 1 3 3 3 0 Laminin EGF domain Cornichon PF03311.14 KKK12714.1 - 6.1e-44 149.3 12.9 2.1e-38 131.4 3.5 2.0 2 0 0 2 2 2 2 Cornichon protein Fungal_trans PF04082.18 KKK12715.1 - 3.3e-26 91.9 0.0 1.7e-25 89.6 0.0 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK12715.1 - 8.1e-10 38.7 13.1 1.5e-09 37.8 13.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pam16 PF03656.13 KKK12716.1 - 1.8e-07 31.2 0.1 4.2e-07 30.0 0.1 1.8 1 1 0 1 1 1 1 Pam16 DnaJ PF00226.31 KKK12716.1 - 4.5e-05 23.5 0.1 9e-05 22.5 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain Ribosomal_L24e PF01246.20 KKK12717.1 - 1.8e-28 98.6 2.1 1.8e-28 98.6 2.1 2.1 2 0 0 2 2 2 1 Ribosomal protein L24e Cpn60_TCP1 PF00118.24 KKK12718.1 - 1.5e-158 528.5 2.9 1.7e-158 528.3 2.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Chromo_shadow PF01393.19 KKK12719.1 - 3.3e-18 65.5 0.1 1.7e-15 56.9 0.0 2.3 2 0 0 2 2 2 2 Chromo shadow domain Chromo PF00385.24 KKK12719.1 - 1.9e-10 40.5 0.8 1.9e-09 37.2 0.1 2.4 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain ORC6 PF05460.13 KKK12719.1 - 0.00054 19.3 3.2 0.00071 19.0 3.2 1.2 1 0 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) DUF908 PF06012.12 KKK12719.1 - 0.22 10.9 0.9 0.28 10.6 0.9 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Rap1_C PF11626.8 KKK12720.1 - 2.9e-22 78.5 0.0 9.2e-22 76.9 0.0 1.9 1 0 0 1 1 1 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_2 PF08914.11 KKK12720.1 - 3.3e-22 78.4 1.0 8.5e-22 77.1 1.0 1.8 1 0 0 1 1 1 1 Rap1 Myb domain BRCT_2 PF16589.5 KKK12720.1 - 1.7e-11 44.4 0.0 4.7e-11 43.0 0.0 1.8 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain Rap1-DNA-bind PF09197.10 KKK12720.1 - 3.6e-06 27.5 0.1 1.8e-05 25.3 0.0 2.1 2 0 0 2 2 2 1 Rap1, DNA-binding Ndc1_Nup PF09531.10 KKK12720.1 - 1.6 7.4 3.6 2 7.0 3.6 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Atx10homo_assoc PF09759.9 KKK12721.1 - 1.6e-33 114.6 0.5 3.9e-33 113.4 0.1 1.8 2 0 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain SLAIN PF15301.6 KKK12721.1 - 0.057 12.7 2.3 0.1 11.9 2.3 1.3 1 0 0 1 1 1 0 SLAIN motif-containing family RNA_pol_3_Rpc31 PF11705.8 KKK12721.1 - 0.063 13.5 6.4 0.13 12.5 6.4 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 zf-RING_2 PF13639.6 KKK12722.1 - 2.3e-08 34.2 2.4 4.5e-08 33.3 2.4 1.5 1 0 0 1 1 1 1 Ring finger domain Putative_PNPOx PF01243.20 KKK12722.1 - 2.7e-08 33.9 0.0 2.8e-05 24.2 0.0 3.1 2 1 0 2 2 2 2 Pyridoxamine 5'-phosphate oxidase zf-rbx1 PF12678.7 KKK12722.1 - 3.7e-05 23.9 3.3 7.7e-05 22.9 2.2 2.1 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KKK12722.1 - 0.0014 18.6 5.5 0.003 17.6 5.5 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 KKK12722.1 - 0.002 18.2 0.4 0.0037 17.3 0.4 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 KKK12722.1 - 0.013 15.2 1.4 0.026 14.3 1.4 1.5 1 0 0 1 1 1 0 RING-like zinc finger zf-C3HC4_2 PF13923.6 KKK12722.1 - 0.014 15.3 3.1 0.027 14.3 2.2 2.0 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) FAD_binding_6 PF00970.24 KKK12722.1 - 0.016 15.6 0.0 0.044 14.1 0.0 1.7 1 1 0 1 1 1 0 Oxidoreductase FAD-binding domain NTP_transferase PF00483.23 KKK12723.1 - 9.4e-32 110.5 0.0 1.4e-31 110.0 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 KKK12723.1 - 5.5e-08 33.3 0.0 1e-07 32.5 0.0 1.5 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep PF00132.24 KKK12723.1 - 1.1e-07 31.3 8.0 1.4e-06 27.7 0.2 3.5 2 1 1 3 3 3 2 Bacterial transferase hexapeptide (six repeats) IspD PF01128.19 KKK12723.1 - 0.0034 17.2 0.0 0.0061 16.3 0.0 1.4 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Fucokinase PF07959.12 KKK12723.1 - 0.013 14.5 0.4 1.3 7.9 0.2 2.4 2 1 0 2 2 2 0 L-fucokinase Glycos_transf_2 PF00535.26 KKK12723.1 - 0.032 14.0 0.0 0.056 13.2 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 DUF2968 PF11180.8 KKK12723.1 - 0.16 11.6 0.1 0.25 10.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) SUIM_assoc PF16619.5 KKK12724.1 - 0.25 11.4 4.7 0.46 10.6 4.7 1.5 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 DUF2070 PF09843.9 KKK12724.1 - 3.7 5.7 16.8 5 5.3 16.8 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) CorA PF01544.18 KKK12725.1 - 3.4e-38 131.6 0.1 5.8e-38 130.9 0.1 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Vac7 PF12751.7 KKK12726.1 - 8.2e-162 539.0 0.1 8.2e-162 539.0 0.1 2.3 2 1 0 2 2 2 1 Vacuolar segregation subunit 7 BUD22 PF09073.10 KKK12730.1 - 0.00018 21.0 10.7 0.00025 20.5 10.7 1.1 1 0 0 1 1 1 1 BUD22 SAPS PF04499.15 KKK12730.1 - 0.13 11.0 0.6 0.17 10.6 0.6 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Kin17_mid PF10357.9 KKK12730.1 - 0.13 12.1 3.1 3.7 7.5 0.3 2.3 2 0 0 2 2 2 0 Domain of Kin17 curved DNA-binding protein Sigma70_ner PF04546.13 KKK12730.1 - 0.32 10.8 11.4 0.56 10.1 1.9 2.2 2 0 0 2 2 2 0 Sigma-70, non-essential region TFIIF_alpha PF05793.12 KKK12730.1 - 0.41 9.2 15.4 0.3 9.6 4.3 2.1 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) RXT2_N PF08595.11 KKK12730.1 - 0.42 10.6 7.6 2 8.4 1.2 2.2 2 0 0 2 2 2 0 RXT2-like, N-terminal FAM176 PF14851.6 KKK12730.1 - 0.59 9.8 12.3 1.9 8.2 2.1 2.3 2 0 0 2 2 2 0 FAM176 family RNA_pol_Rpc4 PF05132.14 KKK12730.1 - 0.68 10.4 4.1 9.8 6.6 0.3 2.2 2 0 0 2 2 2 0 RNA polymerase III RPC4 Presenilin PF01080.17 KKK12730.1 - 1.1 7.9 4.9 2.3 6.9 4.9 1.4 1 0 0 1 1 1 0 Presenilin Connexin PF00029.19 KKK12730.1 - 2.2 8.0 3.2 29 4.3 0.6 2.1 2 0 0 2 2 2 0 Connexin CPSF100_C PF13299.6 KKK12730.1 - 4.1 7.6 7.7 10 6.3 0.3 2.2 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal TFB6 PF17110.5 KKK12730.1 - 5 6.8 8.8 9.7 5.9 1.3 2.2 2 0 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH PH PF00169.29 KKK12731.1 - 6.9e-10 39.4 0.0 6.5e-09 36.3 0.0 2.4 1 1 0 1 1 1 1 PH domain SH3_1 PF00018.28 KKK12731.1 - 7.5e-10 38.3 0.0 1.4e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KKK12731.1 - 1.2e-09 37.8 0.1 2.7e-09 36.7 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SAM_2 PF07647.17 KKK12731.1 - 5.5e-09 36.0 0.1 9.3e-09 35.3 0.1 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_2 PF07653.17 KKK12731.1 - 2.4e-05 23.9 0.1 4.7e-05 23.0 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain PH_11 PF15413.6 KKK12731.1 - 0.0092 16.4 0.0 0.021 15.2 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 KKK12731.1 - 0.049 13.9 0.0 0.14 12.5 0.0 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain DUF2379 PF09543.10 KKK12732.1 - 0.02 15.1 1.0 0.16 12.1 0.5 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2379) GW PF13457.6 KKK12732.1 - 0.12 13.0 0.0 2.6 8.7 0.0 2.5 2 0 0 2 2 2 0 GW (Gly-Tryp) dipeptide domain PH PF00169.29 KKK12733.1 - 1.5e-29 102.5 0.8 5.6e-14 52.5 0.1 2.3 2 0 0 2 2 2 2 PH domain PH_11 PF15413.6 KKK12733.1 - 1e-11 45.1 0.8 0.00063 20.1 0.3 3.7 2 2 0 2 2 2 2 Pleckstrin homology domain PH_9 PF15410.6 KKK12733.1 - 1.7e-11 44.5 0.8 3.4e-06 27.4 0.1 4.0 2 2 0 2 2 2 2 Pleckstrin homology domain PH_2 PF08458.10 KKK12733.1 - 0.0005 20.4 0.1 0.011 16.1 0.0 2.7 2 1 0 2 2 2 1 Plant pleckstrin homology-like region PH_8 PF15409.6 KKK12733.1 - 0.0013 19.0 0.1 0.09 13.1 0.0 2.3 2 0 0 2 2 2 1 Pleckstrin homology domain PH_13 PF16652.5 KKK12733.1 - 0.0036 17.1 0.2 0.13 12.1 0.1 2.2 2 0 0 2 2 2 1 Pleckstrin homology domain PH_6 PF15406.6 KKK12733.1 - 0.024 14.9 0.0 0.72 10.2 0.0 2.6 3 0 0 3 3 3 0 Pleckstrin homology domain Mcp5_PH PF12814.7 KKK12733.1 - 0.1 12.8 0.2 7.7 6.7 0.0 2.7 3 0 0 3 3 3 0 Meiotic cell cortex C-terminal pleckstrin homology EamA PF00892.20 KKK12734.1 - 7.4e-10 39.1 38.2 2.6e-08 34.1 4.1 3.1 3 0 0 3 3 3 2 EamA-like transporter family DUF3955 PF13127.6 KKK12734.1 - 6.2e-08 32.3 1.1 4.2e-07 29.7 1.1 2.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3955) PUNUT PF16913.5 KKK12734.1 - 0.00015 21.1 0.4 0.00015 21.1 0.4 2.3 3 0 0 3 3 3 1 Purine nucleobase transmembrane transport UAA PF08449.11 KKK12734.1 - 0.00017 20.9 8.5 0.00017 20.9 8.5 1.6 2 0 0 2 2 2 1 UAA transporter family SLC35F PF06027.12 KKK12734.1 - 0.003 17.1 10.9 0.003 17.1 10.9 2.3 2 1 0 2 2 2 1 Solute carrier family 35 7tm_7 PF08395.12 KKK12734.1 - 0.033 13.4 0.5 0.033 13.4 0.5 3.4 4 0 0 4 4 4 0 7tm Chemosensory receptor ATG16 PF08614.11 KKK12735.1 - 2.3e-48 165.1 22.7 4.2e-46 157.7 22.7 2.0 1 1 0 1 1 1 1 Autophagy protein 16 (ATG16) IFT57 PF10498.9 KKK12735.1 - 0.0086 15.1 2.6 0.01 14.8 2.6 1.2 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 Golgin_A5 PF09787.9 KKK12735.1 - 0.012 15.1 6.1 0.014 14.9 6.1 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF4201 PF13870.6 KKK12735.1 - 0.014 15.2 12.4 0.013 15.2 10.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) DUF4407 PF14362.6 KKK12735.1 - 0.015 14.7 11.0 0.022 14.1 11.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Spc7 PF08317.11 KKK12735.1 - 0.02 13.8 7.7 0.086 11.7 6.2 1.9 1 1 1 2 2 2 0 Spc7 kinetochore protein UPF0242 PF06785.11 KKK12735.1 - 0.047 13.8 8.3 0.049 13.7 4.0 2.0 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Tropomyosin PF00261.20 KKK12735.1 - 0.062 12.7 11.4 0.12 11.7 11.2 1.7 1 1 0 1 1 1 0 Tropomyosin DUF3450 PF11932.8 KKK12735.1 - 0.071 12.4 7.8 0.093 12.0 6.5 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) Prefoldin_2 PF01920.20 KKK12735.1 - 0.071 13.1 4.1 3.9 7.5 0.1 2.4 1 1 1 2 2 2 0 Prefoldin subunit Nbl1_Borealin_N PF10444.9 KKK12735.1 - 0.08 12.6 0.3 0.08 12.6 0.3 2.2 2 0 0 2 2 2 0 Nbl1 / Borealin N terminal HAUS-augmin3 PF14932.6 KKK12735.1 - 0.1 12.2 3.7 0.11 12.1 2.0 1.6 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 DUF874 PF05917.11 KKK12735.1 - 0.11 11.5 1.9 0.14 11.2 1.9 1.1 1 0 0 1 1 1 0 Helicobacter pylori protein of unknown function (DUF874) FlaC_arch PF05377.11 KKK12735.1 - 0.16 12.4 1.4 18 5.8 0.1 2.5 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) BST2 PF16716.5 KKK12735.1 - 0.3 11.7 4.3 8 7.1 0.1 2.9 2 1 1 3 3 3 0 Bone marrow stromal antigen 2 Occludin_ELL PF07303.13 KKK12735.1 - 0.31 11.8 2.2 4.8 8.0 0.1 2.3 1 1 1 2 2 2 0 Occludin homology domain YabA PF06156.13 KKK12735.1 - 0.34 11.6 5.7 3.4 8.3 1.0 2.6 1 1 1 2 2 2 0 Initiation control protein YabA Nup54 PF13874.6 KKK12735.1 - 0.38 10.8 8.9 2.2 8.4 3.0 2.4 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 GAS PF13851.6 KKK12735.1 - 0.69 9.2 9.3 0.3 10.4 5.6 1.9 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DHR10 PF18595.1 KKK12735.1 - 0.87 9.7 16.4 0.11 12.5 5.7 2.7 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain FAM76 PF16046.5 KKK12735.1 - 1.5 8.2 4.4 1.7 7.9 4.4 1.1 1 0 0 1 1 1 0 FAM76 protein ABC_tran_CTD PF16326.5 KKK12735.1 - 2.5 8.4 11.8 6.2 7.1 6.5 3.5 1 1 2 3 3 3 0 ABC transporter C-terminal domain Sec2p PF06428.11 KKK12735.1 - 3 7.9 11.0 1.2 9.1 6.0 2.5 2 1 0 2 2 2 0 GDP/GTP exchange factor Sec2p Fez1 PF06818.15 KKK12735.1 - 4 7.8 11.4 1.2 9.6 3.5 2.3 1 1 1 2 2 2 0 Fez1 DUF4140 PF13600.6 KKK12735.1 - 6.6 7.2 11.0 6.7 7.2 0.9 2.8 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) SlyX PF04102.12 KKK12735.1 - 6.9 7.4 8.9 11 6.7 1.9 2.9 2 1 1 3 3 2 0 SlyX CCDC-167 PF15188.6 KKK12735.1 - 8.4 6.8 12.3 43 4.5 11.2 2.3 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 DOT1 PF08123.13 KKK12736.1 - 8.5e-59 198.5 0.0 6.5e-47 159.7 0.0 2.2 1 1 1 2 2 2 2 Histone methylation protein DOT1 Thioredoxin_12 PF18400.1 KKK12736.1 - 0.078 12.8 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like domain Spb1_C PF07780.12 KKK12737.1 - 9.6e-84 280.2 25.8 9.6e-84 280.2 25.8 2.6 3 0 0 3 3 3 1 Spb1 C-terminal domain FtsJ PF01728.19 KKK12737.1 - 1.2e-56 191.7 0.0 2.3e-56 190.7 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF3381 PF11861.8 KKK12737.1 - 3.2e-50 170.1 8.6 3.2e-50 170.1 8.6 4.8 5 0 0 5 5 5 1 Domain of unknown function (DUF3381) Methyltransf_23 PF13489.6 KKK12737.1 - 0.015 15.1 0.0 0.041 13.7 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltr_RsmB-F PF01189.17 KKK12737.1 - 0.031 13.9 0.0 0.066 12.8 0.0 1.5 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F E1_FCCH PF16190.5 KKK12737.1 - 0.095 12.9 0.0 0.27 11.5 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin-activating enzyme E1 FCCH domain Ran_BP1 PF00638.18 KKK12739.1 - 2.5e-50 169.8 2.0 2.5e-50 169.8 2.0 1.5 2 0 0 2 2 2 1 RanBP1 domain WH1 PF00568.23 KKK12739.1 - 2e-05 24.5 0.3 0.00015 21.6 0.3 2.1 1 1 0 1 1 1 1 WH1 domain VID27_PH PF17747.1 KKK12739.1 - 0.0022 18.2 0.0 0.0033 17.7 0.0 1.2 1 0 0 1 1 1 1 VID27 PH-like domain DUF4358 PF14270.6 KKK12739.1 - 0.052 13.8 3.8 2.2 8.6 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4358) CDC27 PF09507.10 KKK12739.1 - 0.15 11.4 19.4 0.21 11.0 19.4 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Phasin PF05597.11 KKK12739.1 - 1.5 8.9 7.7 1.7 8.6 0.3 2.9 3 0 0 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF966 PF06136.13 KKK12739.1 - 6.8 6.3 9.8 8.6 6.0 9.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Glyco_transf_15 PF01793.16 KKK12740.1 - 6.7e-95 318.1 11.4 3.3e-94 315.8 11.4 1.8 1 1 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Ras PF00071.22 KKK12741.1 - 7.4e-57 191.5 0.0 8.7e-57 191.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KKK12741.1 - 3e-32 111.3 0.0 4.4e-32 110.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKK12741.1 - 4.2e-13 49.1 0.0 5e-13 48.9 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KKK12741.1 - 2.3e-07 30.9 0.0 3.7e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KKK12741.1 - 1e-05 25.2 0.0 0.00053 19.6 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KKK12741.1 - 1.2e-05 24.8 0.0 1.5e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 KKK12741.1 - 0.00017 21.5 0.1 0.0043 17.0 0.1 2.3 1 1 2 3 3 3 1 RsgA GTPase PduV-EutP PF10662.9 KKK12741.1 - 0.0014 18.3 0.1 0.087 12.6 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.17 KKK12741.1 - 0.0022 17.8 0.2 0.065 13.0 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA_22 PF13401.6 KKK12741.1 - 0.0047 17.2 0.0 0.013 15.7 0.0 1.8 2 1 0 2 2 2 1 AAA domain Septin PF00735.18 KKK12741.1 - 0.0053 16.1 0.1 0.053 12.8 0.0 2.1 2 0 0 2 2 2 1 Septin cobW PF02492.19 KKK12741.1 - 0.0078 15.8 0.0 0.032 13.8 0.0 1.8 1 1 2 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.6 KKK12741.1 - 0.0094 16.3 0.0 0.016 15.6 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.6 KKK12741.1 - 0.013 15.2 0.0 0.023 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 KKK12741.1 - 0.017 15.1 0.0 0.029 14.4 0.0 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) SRPRB PF09439.10 KKK12741.1 - 0.017 14.5 0.0 0.021 14.3 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_7 PF12775.7 KKK12741.1 - 0.027 14.0 0.0 0.065 12.8 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region NTPase_1 PF03266.15 KKK12741.1 - 0.044 13.7 0.0 0.068 13.1 0.0 1.3 1 0 0 1 1 1 0 NTPase ATPase_2 PF01637.18 KKK12741.1 - 0.084 12.8 0.8 0.13 12.1 0.1 1.6 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea TniB PF05621.11 KKK12741.1 - 0.12 11.8 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein NACHT PF05729.12 KKK12741.1 - 0.16 11.9 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 NACHT domain NB-ARC PF00931.22 KKK12741.1 - 0.16 11.1 0.0 0.3 10.3 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain G-alpha PF00503.20 KKK12741.1 - 0.17 11.0 0.4 0.67 9.1 0.2 1.9 2 1 1 3 3 3 0 G-protein alpha subunit AAA_18 PF13238.6 KKK12741.1 - 0.18 12.3 0.0 0.36 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain DNA_ligase_A_M PF01068.21 KKK12742.1 - 4.5e-45 153.8 0.0 9.4e-45 152.8 0.0 1.6 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 KKK12742.1 - 7.2e-44 150.2 0.1 4.7e-43 147.5 0.0 2.3 3 0 0 3 3 3 1 DNA ligase N terminus BRCT_2 PF16589.5 KKK12742.1 - 3e-19 69.2 0.0 1.4e-13 51.1 0.0 2.7 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain DNA_ligase_A_C PF04679.15 KKK12742.1 - 8.5e-17 61.6 0.0 1.8e-15 57.3 0.0 2.9 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 KKK12742.1 - 1.9e-15 57.5 0.0 3.9e-15 56.5 0.0 1.5 1 0 0 1 1 1 1 RNA ligase BRCT PF00533.26 KKK12742.1 - 1.1e-10 41.7 0.0 3.6e-06 27.3 0.0 2.7 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain Fungal_trans PF04082.18 KKK12742.1 - 6e-08 32.0 0.0 1.5e-07 30.7 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain LIG3_BRCT PF16759.5 KKK12742.1 - 1e-06 28.9 0.0 0.0029 17.8 0.0 2.5 2 0 0 2 2 2 2 DNA ligase 3 BRCT domain zf-H2C2_2 PF13465.6 KKK12742.1 - 1.2e-05 25.5 6.2 1.2e-05 25.5 6.2 2.7 3 0 0 3 3 3 1 Zinc-finger double domain Zn_clus PF00172.18 KKK12742.1 - 2.4e-05 24.3 9.6 2.4e-05 24.3 9.6 2.2 3 0 0 3 3 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DNA_ligase_IV PF11411.8 KKK12742.1 - 0.00011 22.3 0.1 0.00021 21.4 0.1 1.5 1 0 0 1 1 1 1 DNA ligase IV zf-C2H2 PF00096.26 KKK12742.1 - 0.00015 22.0 18.4 0.023 15.1 4.8 3.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KKK12742.1 - 0.012 16.3 25.3 0.043 14.6 3.5 3.2 3 0 0 3 3 2 0 C2H2-type zinc finger zf-met PF12874.7 KKK12742.1 - 0.022 15.1 0.7 0.052 14.0 0.7 1.7 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KKK12742.1 - 0.028 14.7 5.7 1.9 8.9 1.3 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2HE PF16278.5 KKK12742.1 - 0.76 10.3 3.0 2e+02 2.5 6.8 2.9 2 1 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger EF-hand_4 PF12763.7 KKK12744.1 - 1.8e-05 24.6 0.1 4e-05 23.5 0.1 1.5 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand Fungal_trans PF04082.18 KKK12745.1 - 7.2e-05 22.0 0.4 7.2e-05 22.0 0.4 2.1 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK12745.1 - 0.021 14.9 9.6 0.058 13.5 9.6 1.8 1 1 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain YEATS PF03366.16 KKK12746.1 - 1.5e-18 66.6 0.0 2.3e-18 65.9 0.0 1.3 1 0 0 1 1 1 1 YEATS family BET PF17035.5 KKK12746.1 - 0.18 12.0 0.0 0.29 11.3 0.0 1.3 1 0 0 1 1 1 0 Bromodomain extra-terminal - transcription regulation AAA_33 PF13671.6 KKK12749.1 - 1.4e-19 70.7 0.0 1.7e-19 70.4 0.0 1.1 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 KKK12749.1 - 0.00056 19.4 0.0 0.00068 19.2 0.0 1.0 1 0 0 1 1 1 1 Chromatin associated protein KTI12 Septin PF00735.18 KKK12750.1 - 5.9e-104 347.3 0.0 1e-103 346.5 0.0 1.4 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 KKK12750.1 - 3.2e-05 24.0 0.0 7.9e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KKK12750.1 - 0.0021 17.6 0.1 0.16 11.5 0.0 2.3 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 KKK12750.1 - 0.0043 17.1 3.8 1 9.4 0.0 3.0 2 1 1 3 3 3 2 Dynamin family RsgA_GTPase PF03193.16 KKK12750.1 - 0.0069 16.3 3.3 0.012 15.6 0.2 2.6 3 1 0 3 3 3 1 RsgA GTPase AIG1 PF04548.16 KKK12750.1 - 0.11 11.8 0.1 0.27 10.5 0.1 1.7 1 1 0 1 1 1 0 AIG1 family Fes1 PF08609.10 KKK12751.1 - 3.2e-32 111.3 5.4 4.2e-31 107.7 3.8 2.5 3 0 0 3 3 3 1 Nucleotide exchange factor Fes1 HEAT_EZ PF13513.6 KKK12751.1 - 1.7e-07 31.5 0.1 8.2e-07 29.4 0.0 2.3 3 0 0 3 3 3 1 HEAT-like repeat HEAT PF02985.22 KKK12751.1 - 3.1e-07 30.1 0.1 0.049 13.9 0.0 2.8 2 0 0 2 2 2 2 HEAT repeat HEAT_2 PF13646.6 KKK12751.1 - 4.2e-07 30.3 0.1 2.3e-06 27.9 0.1 2.2 2 1 0 2 2 2 1 HEAT repeats Arm PF00514.23 KKK12751.1 - 1.2e-06 28.4 0.1 0.0015 18.5 0.0 2.5 2 0 0 2 2 2 2 Armadillo/beta-catenin-like repeat V-ATPase_H_N PF03224.14 KKK12751.1 - 0.054 12.8 0.0 0.06 12.6 0.0 1.1 1 0 0 1 1 1 0 V-ATPase subunit H Adaptin_N PF01602.20 KKK12751.1 - 0.076 11.6 0.1 0.16 10.5 0.1 1.5 1 1 0 1 1 1 0 Adaptin N terminal region PSD2 PF07624.11 KKK12751.1 - 0.084 12.7 0.1 0.36 10.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1585) Membr_traf_MHD PF10540.9 KKK12753.1 - 1.4e-21 77.2 1.4 2.5e-11 44.0 0.6 3.2 2 1 1 3 3 3 2 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.30 KKK12753.1 - 2.5e-15 56.6 0.0 5.5e-15 55.5 0.0 1.6 1 0 0 1 1 1 1 C2 domain DUF810 PF05664.11 KKK12753.1 - 3.4e-09 35.8 3.2 1.8e-07 30.1 0.9 2.9 3 0 0 3 3 3 2 Plant family of unknown function (DUF810) Ribonuc_L-PSP PF01042.21 KKK12754.1 - 1.3e-35 122.1 0.1 1.4e-35 121.9 0.1 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP SNF2_N PF00176.23 KKK12755.1 - 1.7e-65 221.1 0.6 2.8e-65 220.3 0.6 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KKK12755.1 - 2.7e-19 69.5 0.0 8.5e-19 67.9 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KKK12755.1 - 5.7e-10 39.5 0.0 1.3e-09 38.3 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HSA PF07529.13 KKK12755.1 - 6.2e-09 36.1 9.8 6.2e-09 36.1 9.8 2.6 2 0 0 2 2 2 1 HSA DEAD PF00270.29 KKK12755.1 - 0.00012 21.9 0.0 0.0004 20.2 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase DEAD_2 PF06733.15 KKK12755.1 - 0.14 11.7 0.0 0.32 10.6 0.0 1.5 1 0 0 1 1 1 0 DEAD_2 DUF3417 PF11897.8 KKK12755.1 - 0.85 10.1 3.2 3 8.3 3.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3417) NDUF_B8 PF05821.11 KKK12756.1 - 4.7e-09 36.3 1.2 6.8e-09 35.8 1.2 1.3 1 1 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) SUR7 PF06687.12 KKK12758.1 - 2.1e-47 161.5 13.8 2.5e-47 161.2 13.8 1.1 1 0 0 1 1 1 1 SUR7/PalI family SpoIIM PF01944.17 KKK12758.1 - 0.086 12.9 11.4 0.021 14.9 7.6 1.8 2 0 0 2 2 2 0 Stage II sporulation protein M Meckelin PF09773.9 KKK12758.1 - 4.7 5.2 6.9 1.2 7.1 3.6 1.6 2 0 0 2 2 2 0 Meckelin (Transmembrane protein 67) FAD_binding_4 PF01565.23 KKK12760.1 - 4.3e-24 84.8 3.1 7.2e-24 84.1 3.1 1.4 1 0 0 1 1 1 1 FAD binding domain Myb_DNA-binding PF00249.31 KKK12761.1 - 1.9e-14 53.6 2.5 2.6e-11 43.5 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KKK12761.1 - 3e-06 27.4 3.7 0.0026 18.0 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain AGOG PF09171.10 KKK12761.1 - 0.14 11.5 0.1 0.19 11.0 0.1 1.1 1 0 0 1 1 1 0 N-glycosylase/DNA lyase zf-C2H2 PF00096.26 KKK12762.1 - 4.4e-10 39.5 14.1 0.00071 19.9 0.1 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KKK12762.1 - 9.1e-10 38.5 11.8 0.00049 20.7 0.2 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.7 KKK12762.1 - 1.9e-05 24.8 0.3 0.17 12.3 0.3 2.8 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 KKK12762.1 - 0.0037 17.6 10.8 0.2 12.1 0.3 3.3 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_6 PF13912.6 KKK12762.1 - 0.033 14.2 10.6 0.3 11.1 0.3 4.1 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2_2 PF12756.7 KKK12762.1 - 0.11 12.9 3.8 0.48 10.8 0.8 2.6 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 KKK12762.1 - 0.15 12.4 2.6 0.49 10.8 0.0 2.6 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-BED PF02892.15 KKK12762.1 - 1.1 9.3 6.7 12 6.1 0.0 3.1 2 1 1 3 3 3 0 BED zinc finger zf-C2H2_11 PF16622.5 KKK12762.1 - 2.8 7.8 7.5 25 4.7 0.3 3.3 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-C2H2_3rep PF18868.1 KKK12762.1 - 5.8 7.6 6.6 12 6.6 0.8 2.7 1 1 2 3 3 3 0 Zinc finger C2H2-type, 3 repeats zf_UBZ PF18439.1 KKK12762.1 - 9.6 5.9 6.2 36 4.1 0.2 3.2 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger Pkinase PF00069.25 KKK12764.1 - 1.3e-23 83.8 0.0 1.9e-23 83.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain HEAT PF02985.22 KKK12764.1 - 3.6e-10 39.2 11.6 0.027 14.7 0.1 6.8 7 0 0 7 7 7 3 HEAT repeat WD40 PF00400.32 KKK12764.1 - 5.4e-08 33.4 14.2 6.4e-06 26.8 0.1 5.2 5 0 0 5 5 5 2 WD domain, G-beta repeat HEAT_2 PF13646.6 KKK12764.1 - 6.8e-06 26.4 1.8 1.1 9.7 0.0 4.7 4 1 1 5 5 5 2 HEAT repeats HEAT_EZ PF13513.6 KKK12764.1 - 0.00013 22.4 0.9 0.13 12.9 0.1 4.5 4 0 0 4 4 4 1 HEAT-like repeat Pkinase_Tyr PF07714.17 KKK12764.1 - 0.00016 21.1 0.0 0.00026 20.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Tti2 PF10521.9 KKK12764.1 - 0.00065 19.3 0.0 0.0014 18.2 0.0 1.5 1 0 0 1 1 1 1 Tti2 family Cnd1 PF12717.7 KKK12764.1 - 0.013 15.6 0.4 0.26 11.3 0.0 2.9 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 M11L PF11099.8 KKK12764.1 - 0.025 14.9 0.1 1.5 9.1 0.0 2.4 2 0 0 2 2 2 0 Apoptosis regulator M11L like RTP1_C1 PF10363.9 KKK12764.1 - 0.052 13.7 0.2 6 7.1 0.0 2.5 2 0 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 Ge1_WD40 PF16529.5 KKK12764.1 - 0.074 12.0 0.1 0.85 8.5 0.0 2.3 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Adaptin_N PF01602.20 KKK12764.1 - 0.16 10.5 1.5 2.2 6.7 0.2 2.1 2 0 0 2 2 2 0 Adaptin N terminal region zf-ACC PF17848.1 KKK12765.1 - 0.044 13.9 0.0 0.091 12.9 0.0 1.5 1 0 0 1 1 1 0 Acetyl-coA carboxylase zinc finger domain RPA_C PF08784.11 KKK12766.1 - 2.3e-16 60.3 0.0 8.1e-16 58.6 0.0 1.9 2 0 0 2 2 2 1 Replication protein A C terminal tRNA_anti-codon PF01336.25 KKK12766.1 - 0.022 14.8 0.1 0.069 13.1 0.0 1.8 2 1 0 2 2 2 0 OB-fold nucleic acid binding domain HTH_24 PF13412.6 KKK12766.1 - 0.03 13.9 0.0 0.061 12.9 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding MatE PF01554.18 KKK12767.1 - 2.2e-59 199.7 23.9 1.1e-35 122.7 7.5 2.5 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 KKK12767.1 - 0.0019 18.2 8.8 0.0019 18.2 8.8 4.0 3 2 0 4 4 4 1 Polysaccharide biosynthesis C-terminal domain DUF202 PF02656.15 KKK12768.1 - 5.7e-18 65.1 4.5 5.8e-18 65.1 0.4 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Tetraspanin PF00335.20 KKK12768.1 - 0.031 14.0 1.6 0.11 12.2 1.3 1.7 2 0 0 2 2 2 0 Tetraspanin family DUF716 PF04819.12 KKK12768.1 - 0.064 12.9 1.4 0.086 12.5 1.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF716) GWT1 PF06423.12 KKK12768.1 - 0.098 12.8 0.4 0.15 12.2 0.4 1.3 1 1 0 1 1 1 0 GWT1 DUF2976 PF11190.8 KKK12768.1 - 0.12 12.2 2.4 0.16 11.8 0.9 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2976) Yip1 PF04893.17 KKK12768.1 - 0.27 10.9 5.8 0.22 11.2 3.6 1.8 1 1 1 2 2 2 0 Yip1 domain NUDIX PF00293.28 KKK12769.1 - 2.4e-25 89.1 0.0 3.7e-25 88.5 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain DENN PF02141.21 KKK12771.1 - 9.1e-41 139.9 0.1 1.3e-40 139.3 0.1 1.2 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 KKK12771.1 - 0.0002 22.0 3.4 0.00029 21.5 0.1 2.9 4 0 0 4 4 4 1 uDENN domain DEAD PF00270.29 KKK12772.1 - 1.5e-48 164.9 0.3 1.1e-47 162.1 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KKK12772.1 - 4.6e-24 84.9 0.2 1.5e-22 80.0 0.2 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DBP10CT PF08147.12 KKK12772.1 - 7e-21 74.3 0.7 7e-21 74.3 0.7 2.5 2 0 0 2 2 2 1 DBP10CT (NUC160) domain DEAD PF00270.29 KKK12773.1 - 4e-35 121.2 0.0 8.2e-17 61.5 0.0 2.4 1 1 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 KKK12773.1 - 8.8e-19 67.9 0.0 2.4e-18 66.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KKK12773.1 - 6e-07 29.6 0.2 3.9e-06 27.0 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Nop14 PF04147.12 KKK12773.1 - 0.00013 20.4 15.2 0.00013 20.4 15.2 2.1 2 0 0 2 2 2 1 Nop14-like family SDA1 PF05285.12 KKK12773.1 - 0.00061 19.3 17.0 0.00061 19.3 17.0 2.3 2 0 0 2 2 2 1 SDA1 AAA_22 PF13401.6 KKK12773.1 - 0.098 12.9 1.0 7.3 6.9 0.0 3.3 4 0 0 4 4 4 0 AAA domain Macoilin PF09726.9 KKK12773.1 - 0.24 9.9 34.4 0.091 11.3 8.9 2.2 2 0 0 2 2 2 0 Macoilin family Fungal_trans PF04082.18 KKK12774.1 - 7.1e-15 54.7 0.1 1.3e-14 53.9 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK12774.1 - 5.2e-10 39.3 10.5 9.7e-10 38.4 10.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain IL11 PF07400.11 KKK12774.1 - 0.14 11.8 0.3 19 4.9 0.0 2.5 2 0 0 2 2 2 0 Interleukin 11 MIP-T3_C PF17749.1 KKK12774.1 - 0.24 11.4 0.5 0.54 10.2 0.1 1.8 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 C-terminal region TCTP PF00838.17 KKK12775.1 - 7.1e-56 189.1 1.1 8.6e-56 188.8 1.1 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein Ribosomal_S20p PF01649.18 KKK12775.1 - 0.11 13.1 0.2 0.2 12.3 0.2 1.4 1 0 0 1 1 1 0 Ribosomal protein S20 FA_hydroxylase PF04116.13 KKK12776.1 - 8.1e-24 84.5 14.1 1e-23 84.1 12.3 1.9 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily zf-C2H2 PF00096.26 KKK12778.1 - 2.6e-06 27.6 15.6 0.12 12.8 0.1 3.9 3 1 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_aberr PF17017.5 KKK12778.1 - 4.3e-06 27.0 0.8 5.9e-06 26.6 0.1 1.6 2 0 0 2 2 2 1 Aberrant zinc-finger Cnn_1N PF07989.11 KKK12778.1 - 0.0048 17.0 0.7 0.097 12.8 0.7 2.4 2 0 0 2 2 2 1 Centrosomin N-terminal motif 1 HAUS-augmin3 PF14932.6 KKK12778.1 - 0.016 14.8 0.0 0.023 14.3 0.0 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 Transpos_assoc PF13963.6 KKK12778.1 - 0.017 15.5 0.6 0.54 10.6 0.1 2.3 2 0 0 2 2 2 0 Transposase-associated domain FOXP-CC PF16159.5 KKK12778.1 - 0.022 15.4 2.3 4.6 7.9 0.1 2.9 2 1 1 3 3 3 0 FOXP coiled-coil domain CENP-F_leu_zip PF10473.9 KKK12778.1 - 0.035 14.1 0.3 0.075 13.1 0.3 1.5 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 zf-C2H2_4 PF13894.6 KKK12778.1 - 0.042 14.7 9.0 12 7.0 0.7 3.8 3 1 0 3 3 3 0 C2H2-type zinc finger Trimer_CC PF08954.11 KKK12778.1 - 0.074 12.6 4.9 0.17 11.5 4.9 1.5 1 0 0 1 1 1 0 Trimerisation motif zf-C2HE PF16278.5 KKK12778.1 - 0.2 12.1 1.3 0.52 10.8 1.3 1.7 1 0 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger zf-H2C2_2 PF13465.6 KKK12778.1 - 0.45 11.0 0.2 0.45 11.0 0.2 3.5 3 0 0 3 3 3 0 Zinc-finger double domain MCM_OB PF17207.3 KKK12778.1 - 7.1 6.5 6.8 18 5.2 1.5 2.4 1 1 1 2 2 2 0 MCM OB domain SRP19 PF01922.17 KKK12779.1 - 1.6e-36 125.2 0.0 2.3e-36 124.6 0.0 1.3 1 0 0 1 1 1 1 SRP19 protein Dus PF01207.17 KKK12780.1 - 4.1e-44 150.9 0.0 9.6e-32 110.3 0.0 2.7 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) zf_CCCH_4 PF18345.1 KKK12780.1 - 0.00036 20.5 6.1 0.12 12.5 0.5 2.5 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_4 PF18044.1 KKK12780.1 - 0.004 16.9 4.6 0.14 12.0 0.3 2.6 2 0 0 2 2 2 2 CCCH-type zinc finger zf-CCCH PF00642.24 KKK12780.1 - 0.29 11.1 3.2 7.5 6.6 0.4 2.7 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 KKK12780.1 - 8.4 7.1 14.4 0.31 11.8 2.3 2.8 2 1 1 3 3 3 0 Torus domain zf-C2H2 PF00096.26 KKK12781.1 - 5.7e-05 23.3 10.3 0.07 13.6 1.5 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_aberr PF17017.5 KKK12781.1 - 8.7e-05 22.7 1.0 0.048 13.8 0.0 2.3 2 0 0 2 2 2 2 Aberrant zinc-finger zf-C2H2_4 PF13894.6 KKK12781.1 - 0.00028 21.5 11.8 0.03 15.1 1.1 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KKK12781.1 - 0.019 15.2 1.1 1.2 9.6 0.1 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 KKK12781.1 - 0.019 15.4 0.5 0.019 15.4 0.5 3.2 3 0 0 3 3 3 0 Zinc-finger double domain DUF4719 PF15843.5 KKK12781.1 - 0.47 10.5 0.0 0.47 10.5 0.0 3.3 1 1 3 4 4 4 0 Domain of unknown function (DUF4719) HNF-1_N PF04814.13 KKK12781.1 - 2.8 8.5 9.7 0.24 12.0 2.9 2.5 3 0 0 3 3 3 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus TFIIA PF03153.13 KKK12782.1 - 9.1e-77 259.8 7.5 5.3e-50 171.6 1.0 2.0 1 1 1 2 2 2 2 Transcription factor IIA, alpha/beta subunit GST_N_4 PF17172.4 KKK12783.1 - 3.8e-25 88.5 0.0 5.5e-25 88.0 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 KKK12783.1 - 1.7e-06 27.7 0.0 4.5e-06 26.4 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KKK12783.1 - 5.8e-05 23.0 0.1 0.00012 22.0 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 KKK12783.1 - 6.7e-05 23.2 0.0 9.6e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_N_3 PF13417.6 KKK12783.1 - 0.00016 22.0 0.0 0.00078 19.8 0.0 2.0 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Bap31 PF05529.12 KKK12784.1 - 2.3e-47 160.2 6.7 2.9e-47 159.9 6.7 1.1 1 0 0 1 1 1 1 Bap31/Bap29 transmembrane region Bap31_Bap29_C PF18035.1 KKK12784.1 - 5.8e-16 58.2 1.5 1.1e-15 57.3 1.5 1.5 1 0 0 1 1 1 1 Bap31/Bap29 cytoplasmic coiled-coil domain DivIC PF04977.15 KKK12784.1 - 0.0042 16.8 1.8 0.93 9.3 0.0 3.2 3 0 0 3 3 3 2 Septum formation initiator Nup54_57_C PF18570.1 KKK12784.1 - 0.2 11.2 1.2 6.2 6.5 0.0 2.4 1 1 1 2 2 2 0 NUP57/Nup54 C-terminal domain CAMSAP_CC1 PF17095.5 KKK12784.1 - 0.69 9.8 5.8 1.1 9.2 1.2 2.4 1 1 1 2 2 2 0 Spectrin-binding region of Ca2+-Calmodulin Aminotran_3 PF00202.21 KKK12785.1 - 2.2e-37 128.7 0.0 1.6e-19 69.8 0.0 3.1 2 1 0 2 2 2 2 Aminotransferase class-III AAA_26 PF13500.6 KKK12785.1 - 1.1e-21 77.5 0.0 2.1e-21 76.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain BATS PF06968.13 KKK12786.1 - 1.9e-22 79.2 0.2 8.4e-22 77.1 0.0 2.1 2 1 0 2 2 2 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.21 KKK12786.1 - 1.1e-15 58.4 0.0 3.3e-14 53.6 0.0 2.6 3 0 0 3 3 3 1 Radical SAM superfamily P33MONOX PF15302.6 KKK12786.1 - 0.11 12.2 0.0 0.26 10.9 0.0 1.5 1 0 0 1 1 1 0 P33 mono-oxygenase Cation_ATPase_C PF00689.21 KKK12787.1 - 5.4e-25 88.2 11.6 5.4e-25 88.2 11.6 2.1 2 1 0 2 2 2 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 KKK12787.1 - 1.2e-19 70.5 7.4 1.8e-13 50.4 0.0 2.7 2 0 0 2 2 2 2 E1-E2 ATPase Hydrolase PF00702.26 KKK12787.1 - 2.2e-18 67.3 0.1 4.3e-17 63.1 0.1 2.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KKK12787.1 - 1.3e-15 57.3 0.0 3.3e-15 55.9 0.0 1.7 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KKK12787.1 - 0.00035 20.4 0.1 0.015 15.1 0.2 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Aminotran_1_2 PF00155.21 KKK12788.1 - 5.7e-38 131.0 0.0 6.7e-38 130.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KKK12788.1 - 0.013 14.1 0.0 0.017 13.7 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Aminotran_3 PF00202.21 KKK12788.1 - 0.027 13.1 0.0 0.036 12.7 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-III DUF952 PF06108.12 KKK12789.1 - 1.2e-20 73.3 0.0 1.6e-20 72.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF952) IMPDH PF00478.25 KKK12790.1 - 1.3e-126 422.3 4.0 1.5e-126 422.1 4.0 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 KKK12790.1 - 1.1e-18 67.4 0.0 7e-10 39.2 0.0 2.5 2 0 0 2 2 2 2 CBS domain NMO PF03060.15 KKK12790.1 - 2.5e-05 23.9 4.0 0.065 12.6 4.3 2.7 2 1 1 3 3 3 2 Nitronate monooxygenase FMN_dh PF01070.18 KKK12790.1 - 5.4e-05 22.4 0.5 0.00015 21.0 0.5 1.8 1 0 0 1 1 1 1 FMN-dependent dehydrogenase His_biosynth PF00977.21 KKK12790.1 - 0.00062 19.3 2.7 0.0068 15.9 2.7 2.1 1 1 0 1 1 1 1 Histidine biosynthesis protein YpsA PF06908.11 KKK12790.1 - 0.0048 16.9 0.0 0.0092 16.0 0.0 1.4 1 0 0 1 1 1 1 YspA SLOG family PK PF00224.21 KKK12790.1 - 0.042 12.7 0.0 0.11 11.3 0.0 1.6 1 1 1 2 2 2 0 Pyruvate kinase, barrel domain RasGAP PF00616.19 KKK12791.1 - 2.1e-53 181.2 0.0 7.4e-53 179.3 0.0 2.0 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 KKK12791.1 - 1.3e-49 167.9 4.8 1.3e-49 167.9 4.8 3.2 3 1 0 3 3 3 1 RasGAP C-terminus CH PF00307.31 KKK12791.1 - 7.7e-11 42.1 0.0 5.1e-10 39.5 0.0 2.3 2 0 0 2 2 2 1 Calponin homology (CH) domain IQ PF00612.27 KKK12791.1 - 1.6e-07 30.5 51.3 0.21 11.4 0.0 14.9 17 0 0 17 17 17 4 IQ calmodulin-binding motif Trypan_PARP PF05887.11 KKK12791.1 - 0.013 15.5 0.1 0.013 15.5 0.1 1.8 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) ENTH PF01417.20 KKK12792.1 - 3e-45 153.3 0.1 4.2e-45 152.8 0.1 1.2 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 KKK12792.1 - 2.9e-05 23.2 0.0 4.3e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 ANTH domain VHS PF00790.19 KKK12792.1 - 0.053 13.4 0.1 0.092 12.6 0.1 1.4 1 0 0 1 1 1 0 VHS domain DUF5102 PF17104.5 KKK12792.1 - 0.1 12.6 4.6 2.8 7.9 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5102) Velvet PF11754.8 KKK12807.1 - 3.1e-50 171.4 0.1 2e-31 109.8 0.0 3.9 2 2 1 3 3 3 2 Velvet factor Peptidase_M13_N PF05649.13 KKK12809.1 - 1.4e-93 314.6 0.0 1.9e-93 314.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 KKK12809.1 - 7.3e-54 182.5 0.0 1.3e-53 181.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M13 DUF3149 PF11346.8 KKK12809.1 - 0.019 14.6 0.0 0.034 13.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3149) p450 PF00067.22 KKK12844.1 - 2.4e-19 69.4 0.0 2.9e-19 69.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 YiiD_C PF09500.10 KKK12844.1 - 0.16 11.8 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 Putative thioesterase (yiiD_Cterm) Fungal_trans PF04082.18 KKK12851.1 - 1.9e-13 50.0 0.9 2.9e-13 49.4 0.9 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK12851.1 - 3.3e-07 30.3 11.5 7.6e-07 29.2 11.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DnaJ PF00226.31 KKK12852.1 - 1.1e-17 63.9 0.1 1.6e-17 63.3 0.1 1.3 1 0 0 1 1 1 1 DnaJ domain UPF0029 PF01205.19 KKK12853.1 - 1.3e-32 112.3 0.1 2.6e-32 111.3 0.0 1.5 2 0 0 2 2 2 1 Uncharacterized protein family UPF0029 RWD PF05773.22 KKK12853.1 - 2.8e-07 30.8 0.3 4e-07 30.3 0.3 1.3 1 0 0 1 1 1 1 RWD domain Casein_kappa PF00997.18 KKK12853.1 - 5.9 7.0 11.6 11 6.1 11.6 1.3 1 0 0 1 1 1 0 Kappa casein Tetraspanin PF00335.20 KKK12854.1 - 0.082 12.6 3.9 2.5 7.7 0.2 2.7 3 0 0 3 3 3 0 Tetraspanin family LPMO_10 PF03067.15 KKK12855.1 - 0.0011 19.7 0.0 0.0026 18.5 0.0 1.6 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Glyco_hydro_61 PF03443.14 KKK12855.1 - 0.0012 18.9 0.0 0.0025 17.8 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 NUDE_C PF04880.13 KKK12855.1 - 4.6 7.7 7.9 7.3 7.0 7.9 1.4 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region Ribosomal_L4 PF00573.22 KKK12856.1 - 2.2e-38 131.9 0.5 3e-38 131.5 0.5 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 KKK12856.1 - 5.5e-31 106.4 1.0 1.3e-30 105.3 1.0 1.7 1 0 0 1 1 1 1 60S ribosomal protein L4 C-terminal domain LCCL PF03815.19 KKK12857.1 - 9.5e-24 83.3 0.1 1.5e-23 82.7 0.1 1.3 1 0 0 1 1 1 1 LCCL domain Longin_2 PF18639.1 KKK12857.1 - 0.16 11.8 0.0 0.25 11.2 0.0 1.2 1 0 0 1 1 1 0 Yeast longin domain Aminotran_1_2 PF00155.21 KKK12858.1 - 6.1e-05 22.4 0.0 0.00011 21.5 0.0 1.7 1 1 0 1 1 1 1 Aminotransferase class I and II TauD PF02668.16 KKK12866.1 - 1.1e-44 153.3 0.1 1.6e-44 152.7 0.1 1.3 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 KKK12866.1 - 1.1e-05 26.0 0.0 2.8e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF971) CsiD PF08943.10 KKK12866.1 - 0.00035 19.8 0.1 0.00076 18.7 0.1 1.6 1 1 0 1 1 1 1 CsiD 2OG-FeII_Oxy_3 PF13640.6 KKK12866.1 - 0.044 14.7 0.2 0.45 11.4 0.2 2.3 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Ponericin PF07442.11 KKK12866.1 - 8.9 6.4 5.7 4 7.6 1.3 2.2 2 0 0 2 2 2 0 Ponericin Inositol_P PF00459.25 KKK12867.1 - 2.4e-83 279.8 0.0 2.7e-83 279.6 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family DHquinase_II PF01220.19 KKK12868.1 - 9.6e-64 213.2 0.1 1.1e-63 213.0 0.1 1.0 1 0 0 1 1 1 1 Dehydroquinase class II CFEM PF05730.11 KKK12869.1 - 5.5e-15 55.2 11.3 8.9e-15 54.5 11.3 1.3 1 0 0 1 1 1 1 CFEM domain DUF908 PF06012.12 KKK12869.1 - 0.51 9.7 9.1 0.6 9.5 9.1 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Apt1 PF10351.9 KKK12869.1 - 0.55 9.0 5.3 0.6 8.9 5.3 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain SOG2 PF10428.9 KKK12869.1 - 0.63 9.2 16.1 0.71 9.0 16.1 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein IMUP PF15761.5 KKK12869.1 - 2.2 9.0 13.9 4.6 8.0 13.9 1.6 1 0 0 1 1 1 0 Immortalisation up-regulated protein SPX PF03105.19 KKK12869.1 - 2.2 8.1 9.2 2.6 7.9 9.2 1.0 1 0 0 1 1 1 0 SPX domain zf-C3HC4_3 PF13920.6 KKK12870.1 - 1e-09 38.1 11.3 1.6e-09 37.4 11.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KKK12870.1 - 0.0068 16.2 12.3 0.012 15.4 12.3 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Arrestin_C PF02752.22 KKK12871.1 - 5.1e-12 46.4 0.0 2e-11 44.5 0.0 1.9 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain DNA_pol_delta_4 PF04081.13 KKK12872.1 - 7.1e-36 123.4 0.5 1e-35 122.9 0.5 1.3 1 0 0 1 1 1 1 DNA polymerase delta, subunit 4 NADPH_Ox PF08414.10 KKK12872.1 - 0.051 13.9 0.1 0.96 9.8 0.1 2.2 2 0 0 2 2 2 0 Respiratory burst NADPH oxidase Pkinase PF00069.25 KKK12874.1 - 1.3e-17 64.1 0.0 4.4e-17 62.3 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK12874.1 - 2.2e-12 46.8 0.0 7.1e-12 45.1 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KKK12874.1 - 0.035 13.4 0.0 0.055 12.8 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YccV-like PF08755.11 KKK12880.1 - 3.5e-27 94.8 0.0 7.5e-27 93.7 0.0 1.6 1 0 0 1 1 1 1 Hemimethylated DNA-binding protein YccV like Transglut_core2 PF13369.6 KKK12880.1 - 5.5e-11 42.3 0.0 9.5e-11 41.5 0.0 1.4 1 0 0 1 1 1 1 Transglutaminase-like superfamily Sugar_tr PF00083.24 KKK12881.1 - 3.5e-109 365.7 27.3 4e-109 365.5 27.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKK12881.1 - 2.2e-22 79.5 34.7 4.6e-16 58.7 12.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KKK12881.1 - 7.6e-05 21.4 23.6 0.0004 19.1 2.0 3.8 2 2 0 3 3 3 2 MFS/sugar transport protein Glyco_hydro_92 PF07971.12 KKK12882.1 - 2.6e-23 82.7 0.0 2.9e-23 82.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 CSN8_PSD8_EIF3K PF10075.9 KKK12883.1 - 6.3e-48 162.4 0.1 8.2e-48 162.1 0.1 1.1 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family OB_Dis3 PF17849.1 KKK12883.1 - 0.039 14.0 0.0 0.075 13.1 0.0 1.4 1 0 0 1 1 1 0 Dis3-like cold-shock domain 2 (CSD2) LisH PF08513.11 KKK12892.1 - 1.9e-05 24.4 0.2 3.7e-05 23.5 0.2 1.5 1 0 0 1 1 1 1 LisH Septin PF00735.18 KKK12897.1 - 4e-110 367.5 0.7 5.3e-110 367.1 0.6 1.3 1 1 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 KKK12897.1 - 3e-07 30.5 0.0 6.4e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KKK12897.1 - 6.4e-07 29.1 2.4 2.2e-05 24.1 0.2 2.5 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KKK12897.1 - 6.5e-06 26.1 1.0 7.9e-05 22.6 0.1 2.6 3 0 0 3 3 3 1 RsgA GTPase AAA_22 PF13401.6 KKK12897.1 - 0.00082 19.7 0.6 0.0021 18.3 0.1 2.1 2 1 0 2 2 2 1 AAA domain Pox_A32 PF04665.12 KKK12897.1 - 0.0035 16.9 0.1 0.0061 16.0 0.1 1.3 1 0 0 1 1 1 1 Poxvirus A32 protein FOXP-CC PF16159.5 KKK12897.1 - 0.005 17.4 0.5 0.016 15.8 0.5 1.8 1 0 0 1 1 1 1 FOXP coiled-coil domain Roc PF08477.13 KKK12897.1 - 0.006 16.8 0.1 0.014 15.6 0.1 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase IIGP PF05049.13 KKK12897.1 - 0.0065 15.6 0.0 0.013 14.6 0.0 1.5 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) AIG1 PF04548.16 KKK12897.1 - 0.0089 15.4 0.3 0.022 14.1 0.0 1.8 2 0 0 2 2 2 1 AIG1 family AAA_24 PF13479.6 KKK12897.1 - 0.015 15.1 0.0 0.025 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KKK12897.1 - 0.024 15.0 0.5 0.057 13.8 0.0 2.1 2 1 0 2 2 2 0 AAA ATPase domain ABC_tran PF00005.27 KKK12897.1 - 0.024 15.1 0.2 0.15 12.6 0.0 2.2 2 0 0 2 2 2 0 ABC transporter KAP_NTPase PF07693.14 KKK12897.1 - 0.025 13.8 0.0 0.035 13.3 0.0 1.5 1 1 0 1 1 1 0 KAP family P-loop domain Ras PF00071.22 KKK12897.1 - 0.043 13.4 0.7 0.13 11.8 0.4 2.0 2 1 0 2 2 2 0 Ras family NACHT PF05729.12 KKK12897.1 - 0.05 13.5 0.0 0.091 12.7 0.0 1.4 1 0 0 1 1 1 0 NACHT domain PduV-EutP PF10662.9 KKK12897.1 - 0.15 11.8 1.2 4.4 7.0 0.3 2.6 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.17 KKK12897.1 - 0.27 11.0 1.5 12 5.6 0.1 2.8 3 1 1 4 4 4 0 Conserved hypothetical ATP binding protein Dynamin_N PF00350.23 KKK12897.1 - 0.59 10.2 5.9 4.8 7.2 0.1 3.0 2 1 1 3 3 3 0 Dynamin family Atg14 PF10186.9 KKK12897.1 - 1.2 8.1 6.0 2.4 7.2 6.0 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Casc1_N PF15927.5 KKK12897.1 - 4.9 6.8 13.7 0.3 10.7 8.1 1.7 2 0 0 2 2 2 0 Cancer susceptibility candidate 1 N-terminus APG6_N PF17675.1 KKK12897.1 - 8.1 7.0 13.3 1.5 9.3 8.9 1.9 2 0 0 2 2 2 0 Apg6 coiled-coil region WD40 PF00400.32 KKK12898.1 - 9.5e-25 86.4 13.3 0.00024 21.8 0.4 6.8 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKK12898.1 - 2.6e-13 50.1 0.2 0.0095 16.2 0.0 4.9 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain PQQ PF01011.21 KKK12898.1 - 0.00017 21.3 0.0 0.0055 16.6 0.0 3.0 2 0 0 2 2 2 1 PQQ enzyme repeat VID27 PF08553.10 KKK12898.1 - 0.0014 17.8 0.0 0.0021 17.2 0.0 1.3 1 0 0 1 1 1 1 VID27 C-terminal WD40-like domain Ge1_WD40 PF16529.5 KKK12898.1 - 0.13 11.2 0.4 13 4.6 0.1 3.0 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_3 PF13570.6 KKK12898.1 - 0.21 12.1 4.7 1.8 9.2 0.1 4.0 4 0 0 4 4 4 0 PQQ-like domain p450 PF00067.22 KKK12899.1 - 1.2e-33 116.6 0.0 1.4e-33 116.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF4233 PF14017.6 KKK12899.1 - 4.2 7.8 5.2 0.87 10.0 1.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4233) WD40 PF00400.32 KKK12900.1 - 7e-40 134.3 27.5 3.4e-09 37.2 0.1 12.6 13 0 0 13 13 12 6 WD domain, G-beta repeat Utp12 PF04003.12 KKK12900.1 - 1.1e-26 93.2 0.0 1.8e-26 92.6 0.0 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 KKK12900.1 - 2.7e-21 75.6 0.0 0.001 19.3 0.0 9.6 4 2 5 11 11 11 7 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KKK12900.1 - 4.6e-10 39.0 0.4 0.13 11.2 0.0 4.5 2 2 2 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KKK12900.1 - 1.4e-06 28.3 0.2 0.004 17.0 0.2 4.9 5 1 1 6 6 6 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KKK12900.1 - 1.5e-05 23.9 5.1 0.77 8.3 0.0 5.1 2 2 2 4 4 4 2 Nucleoporin Nup120/160 PD40 PF07676.12 KKK12900.1 - 0.0042 17.0 0.1 31 4.7 0.0 5.4 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat PQQ_3 PF13570.6 KKK12900.1 - 0.025 15.1 3.3 22 5.7 0.2 5.1 5 0 0 5 5 5 0 PQQ-like domain Nbas_N PF15492.6 KKK12900.1 - 0.035 13.4 0.1 12 5.1 0.0 3.3 3 1 0 3 3 3 0 Neuroblastoma-amplified sequence, N terminal WD40_like PF17005.5 KKK12900.1 - 0.049 13.0 0.1 0.95 8.7 0.0 2.9 3 0 0 3 3 3 0 WD40-like domain DUF1513 PF07433.11 KKK12900.1 - 0.072 12.2 0.6 1.3 8.0 0.0 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1513) PQQ PF01011.21 KKK12900.1 - 0.23 11.5 0.5 5.4 7.1 0.0 3.4 4 0 0 4 4 4 0 PQQ enzyme repeat CAF1C_H4-bd PF12265.8 KKK12901.1 - 2.7e-28 98.0 1.1 1.2e-27 95.9 1.1 2.1 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 KKK12901.1 - 4e-27 93.9 7.6 0.00014 22.6 0.1 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKK12901.1 - 1.8e-06 28.2 0.8 0.29 11.4 0.0 4.9 2 1 4 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain DUF3751 PF12571.8 KKK12901.1 - 0.089 12.9 0.0 2.4 8.2 0.0 2.4 2 0 0 2 2 2 0 Phage tail-collar fibre protein Nup160 PF11715.8 KKK12901.1 - 0.099 11.3 2.5 7.8 5.0 0.1 3.8 1 1 1 3 3 3 0 Nucleoporin Nup120/160 XRN_M PF17846.1 KKK12902.1 - 1.6e-99 333.9 3.1 2.6e-99 333.2 3.1 1.3 1 0 0 1 1 1 1 Xrn1 helical domain XRN_N PF03159.18 KKK12902.1 - 1.5e-96 322.5 0.0 1.5e-96 322.5 0.0 1.9 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus XRN1_D1 PF18332.1 KKK12902.1 - 9.9e-75 250.5 2.3 1e-74 250.5 0.0 2.0 2 0 0 2 2 2 1 Exoribonuclease Xrn1 D1 domain XRN1_D2_D3 PF18334.1 KKK12902.1 - 7.6e-31 106.2 0.4 2.1e-30 104.7 0.0 2.0 2 0 0 2 2 2 1 Exoribonuclease Xrn1 D2/D3 domain SH3_12 PF18129.1 KKK12902.1 - 4.2e-23 81.2 0.7 9.7e-23 80.1 0.7 1.7 1 0 0 1 1 1 1 Xrn1 SH3-like domain Xrn1_D3 PF18194.1 KKK12902.1 - 3.6e-06 27.0 0.2 9e-06 25.7 0.2 1.6 1 0 0 1 1 1 1 Exoribonuclease 1 Domain-3 GTP_cyclohydroI PF01227.22 KKK12903.1 - 1.7e-73 245.9 0.2 2.1e-73 245.6 0.2 1.1 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.6 KKK12903.1 - 0.0076 16.4 0.0 0.015 15.5 0.0 1.4 1 0 0 1 1 1 1 QueF-like protein Endosulfine PF04667.17 KKK12904.1 - 3.3e-29 100.8 0.1 5.2e-29 100.2 0.1 1.3 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region PhyH PF05721.13 KKK12905.1 - 2.9e-27 96.3 0.0 3.5e-27 96.0 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.6 KKK12905.1 - 0.016 15.6 0.0 0.031 14.7 0.0 1.5 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase DUF1479 PF07350.12 KKK12905.1 - 0.084 11.6 0.0 0.18 10.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1479) NmrA PF05368.13 KKK12906.1 - 1.2e-34 119.8 0.0 1.8e-34 119.4 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KKK12906.1 - 7e-12 45.6 0.5 1e-11 45.1 0.5 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 KKK12906.1 - 2.2e-06 28.0 0.1 3.6e-06 27.3 0.1 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 KKK12906.1 - 0.0017 18.8 0.1 0.0051 17.2 0.0 1.8 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.21 KKK12906.1 - 0.011 15.2 0.1 0.021 14.3 0.1 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DapB_N PF01113.20 KKK12906.1 - 0.053 13.6 0.1 0.099 12.8 0.1 1.5 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Methyltransf_25 PF13649.6 KKK12906.1 - 0.067 13.9 0.0 2.6 8.8 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain TrkA_N PF02254.18 KKK12906.1 - 0.092 13.0 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain DUF4777 PF16007.5 KKK12906.1 - 0.093 13.0 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4777) KR PF08659.10 KKK12906.1 - 0.098 12.6 0.3 0.16 11.9 0.3 1.4 1 1 0 1 1 1 0 KR domain Torus PF16131.5 KKK12907.1 - 2.8e-09 37.6 0.5 2.8e-09 37.6 0.5 2.1 3 0 0 3 3 3 1 Torus domain RRM_1 PF00076.22 KKK12907.1 - 3.8e-09 36.2 0.0 9.4e-09 35.0 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KKK12907.1 - 0.0034 17.3 0.0 0.0062 16.5 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Alpha_Helical PF18489.1 KKK12907.1 - 0.052 13.7 0.0 0.081 13.1 0.0 1.2 1 0 0 1 1 1 0 Alpha helical domain Cut12 PF11500.8 KKK12908.1 - 2.6e-46 157.1 16.5 2.6e-46 157.1 16.5 4.2 3 1 1 4 4 4 1 Spindle pole body formation-associated protein HECW1_helix PF18436.1 KKK12908.1 - 0.15 12.2 0.1 0.51 10.5 0.1 1.9 1 0 0 1 1 1 0 Helical box domain of E3 ubiquitin-protein ligase HECW1 DUF2399 PF09664.10 KKK12908.1 - 0.51 10.2 3.8 1.7 8.5 2.1 2.5 2 0 0 2 2 2 0 Protein of unknown function C-terminus (DUF2399) Baculo_F PF12259.8 KKK12908.1 - 2.2 6.7 9.5 3.9 5.9 9.5 1.3 1 0 0 1 1 1 0 Baculovirus F protein Band_7 PF01145.25 KKK12908.1 - 8.6 6.3 13.5 4.3 7.3 5.8 2.4 2 0 0 2 2 2 0 SPFH domain / Band 7 family HGTP_anticodon2 PF12745.7 KKK12909.1 - 2.1e-84 283.2 0.4 2.1e-84 283.2 0.4 2.3 2 0 0 2 2 2 1 Anticodon binding domain of tRNAs Pkinase PF00069.25 KKK12909.1 - 1.8e-67 227.5 0.0 3.3e-35 121.7 0.0 4.1 4 1 0 4 4 4 3 Protein kinase domain Pkinase_Tyr PF07714.17 KKK12909.1 - 2.2e-40 138.6 0.0 2.2e-18 66.5 0.0 3.6 3 1 0 3 3 3 3 Protein tyrosine kinase RWD PF05773.22 KKK12909.1 - 1.1e-18 67.6 0.0 2.3e-18 66.5 0.0 1.6 1 0 0 1 1 1 1 RWD domain tRNA-synt_His PF13393.6 KKK12909.1 - 3.6e-11 42.9 0.1 1.5e-10 40.8 0.0 2.0 2 0 0 2 2 2 1 Histidyl-tRNA synthetase APH PF01636.23 KKK12909.1 - 5.7e-05 23.1 2.8 0.00055 19.9 0.0 2.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KKK12909.1 - 0.0099 15.2 0.0 3.7 6.8 0.0 2.4 2 0 0 2 2 2 2 Kinase-like HGTP_anticodon PF03129.20 KKK12909.1 - 0.047 13.9 0.0 0.12 12.5 0.0 1.7 1 0 0 1 1 1 0 Anticodon binding domain DUF1682 PF07946.14 KKK12909.1 - 0.55 9.4 7.3 0.87 8.7 7.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) GCIP PF13324.6 KKK12909.1 - 3.7 7.1 4.7 5.8 6.4 3.8 1.7 2 0 0 2 2 2 0 Grap2 and cyclin-D-interacting adh_short_C2 PF13561.6 KKK12910.1 - 7.5e-27 94.4 0.4 9.3e-27 94.1 0.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KKK12910.1 - 1.6e-18 66.9 0.1 2.1e-18 66.5 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KKK12910.1 - 6.3e-06 26.2 0.0 8.8e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_7 PF13241.6 KKK12910.1 - 0.0023 18.4 0.1 0.0072 16.8 0.0 1.8 2 0 0 2 2 2 1 Putative NAD(P)-binding THF_DHG_CYH_C PF02882.19 KKK12910.1 - 0.029 13.7 0.2 0.13 11.6 0.0 2.0 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.21 KKK12910.1 - 0.086 12.3 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family FAD_binding_3 PF01494.19 KKK12911.1 - 4.6e-18 65.6 0.7 4e-17 62.5 0.6 2.3 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KKK12911.1 - 1e-07 31.9 3.6 0.0012 18.6 0.0 2.8 1 1 1 3 3 3 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KKK12911.1 - 3.1e-06 26.6 0.4 5.6e-06 25.7 0.4 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KKK12911.1 - 0.00019 20.8 0.1 0.013 14.8 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KKK12911.1 - 0.002 16.9 0.2 0.0083 14.9 0.3 1.7 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.6 KKK12911.1 - 0.0034 17.6 0.3 0.01 16.1 0.3 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 KKK12911.1 - 0.012 14.7 0.2 0.017 14.2 0.2 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A FAD_oxidored PF12831.7 KKK12911.1 - 0.013 14.9 0.2 0.019 14.4 0.2 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KKK12911.1 - 0.18 11.0 0.2 1.2 8.3 0.4 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_DMAT PF11991.8 KKK12912.1 - 5.7e-94 315.5 0.0 6.9e-94 315.2 0.0 1.1 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase Methyltransf_31 PF13847.6 KKK12913.1 - 3e-10 40.1 0.0 7.7e-10 38.8 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKK12913.1 - 1.2e-09 38.7 0.3 3.9e-09 37.1 0.1 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KKK12913.1 - 1.8e-06 28.6 0.1 7.3e-06 26.6 0.1 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KKK12913.1 - 6.4e-06 26.1 0.0 1.9e-05 24.6 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KKK12913.1 - 4.1e-05 24.2 0.1 0.00016 22.2 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain CheR PF01739.18 KKK12913.1 - 0.00046 19.7 0.0 0.00066 19.2 0.0 1.2 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain Methyltransf_4 PF02390.17 KKK12913.1 - 0.029 13.8 0.0 0.047 13.1 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Ubie_methyltran PF01209.18 KKK12913.1 - 0.062 12.6 0.0 0.098 12.0 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family p450 PF00067.22 KKK12914.1 - 3.9e-38 131.4 0.0 1.2e-20 73.8 0.0 3.1 1 1 2 3 3 3 3 Cytochrome P450 NmrA PF05368.13 KKK12915.1 - 3e-29 102.2 0.0 4.5e-29 101.7 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KKK12915.1 - 7.9e-11 42.2 0.1 1.1e-10 41.7 0.1 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 KKK12915.1 - 0.00014 22.2 0.0 0.00027 21.2 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain PALP PF00291.25 KKK12915.1 - 0.002 17.6 0.1 0.0033 16.9 0.1 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Epimerase PF01370.21 KKK12915.1 - 0.037 13.5 0.1 0.061 12.8 0.1 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family KR PF08659.10 KKK12915.1 - 0.099 12.5 0.2 0.16 11.9 0.2 1.3 1 0 0 1 1 1 0 KR domain DapB_N PF01113.20 KKK12915.1 - 0.15 12.2 0.2 0.26 11.4 0.2 1.3 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.24 KKK12915.1 - 0.18 12.2 0.1 0.37 11.2 0.1 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain p450 PF00067.22 KKK12916.1 - 5.3e-42 144.1 0.0 7.1e-42 143.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KKK12917.1 - 2.2e-41 142.1 0.0 5.2e-41 140.9 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 AMP-binding PF00501.28 KKK12918.1 - 1.4e-139 465.3 0.1 1.2e-71 241.6 0.0 2.4 2 0 0 2 2 2 2 AMP-binding enzyme NAD_binding_4 PF07993.12 KKK12918.1 - 1.9e-39 135.4 0.0 4.1e-39 134.3 0.0 1.6 1 1 0 1 1 1 1 Male sterility protein Condensation PF00668.20 KKK12918.1 - 1.6e-35 122.7 0.0 5.6e-35 120.9 0.0 1.9 2 1 0 2 2 2 1 Condensation domain PP-binding PF00550.25 KKK12918.1 - 8.9e-16 58.0 2.6 8.3e-08 32.5 0.2 3.1 3 0 0 3 3 3 2 Phosphopantetheine attachment site Epimerase PF01370.21 KKK12918.1 - 8.7e-07 28.6 0.0 8.2e-06 25.4 0.0 2.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KKK12918.1 - 0.01 15.0 0.0 4.4 6.4 0.0 2.5 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein AMP-binding_C PF13193.6 KKK12918.1 - 0.14 13.1 0.0 6.3 7.9 0.0 3.0 2 0 0 2 2 2 0 AMP-binding enzyme C-terminal domain 3Beta_HSD PF01073.19 KKK12918.1 - 0.14 11.1 0.0 0.33 9.9 0.0 1.6 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DUF89 PF01937.19 KKK12919.1 - 1.3e-138 461.8 0.0 1.5e-138 461.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 PhyH PF05721.13 KKK12920.1 - 8.7e-23 81.7 0.0 1.2e-22 81.2 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.12 KKK12920.1 - 1.2e-06 27.6 0.1 3.9e-06 25.9 0.0 1.8 2 1 0 2 2 2 1 Protein of unknown function (DUF1479) Trp_DMAT PF11991.8 KKK12921.1 - 2.5e-90 303.5 0.0 3e-90 303.3 0.0 1.1 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase p450 PF00067.22 KKK12922.1 - 2e-24 86.2 0.0 3.5e-24 85.4 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 NmrA PF05368.13 KKK12923.1 - 5e-34 117.9 0.0 6.9e-34 117.4 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KKK12923.1 - 4.7e-09 36.4 0.3 7.1e-09 35.8 0.3 1.2 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KKK12923.1 - 0.01 14.8 0.0 0.017 14.1 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.18 KKK12923.1 - 0.042 14.1 0.0 0.072 13.4 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain PhyH PF05721.13 KKK12924.1 - 6.8e-21 75.5 0.1 1.2e-20 74.6 0.1 1.4 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.12 KKK12924.1 - 0.00046 19.1 0.0 0.0014 17.4 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1479) FAD_binding_4 PF01565.23 KKK12925.1 - 4.7e-20 71.8 2.2 1.2e-19 70.5 2.2 1.7 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KKK12925.1 - 1.3e-05 25.2 0.0 2.6e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like NmrA PF05368.13 KKK12926.1 - 2.6e-30 105.7 0.0 3.4e-30 105.3 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KKK12926.1 - 6e-14 52.4 0.0 9e-14 51.8 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KKK12926.1 - 0.00032 19.8 0.0 0.00049 19.2 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KKK12926.1 - 0.00078 19.0 0.0 0.0012 18.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 KKK12926.1 - 0.0028 17.9 0.0 0.0068 16.7 0.0 1.6 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain F420_oxidored PF03807.17 KKK12926.1 - 0.0037 17.8 0.0 0.022 15.3 0.0 2.3 3 0 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.18 KKK12926.1 - 0.0095 16.2 0.1 0.02 15.1 0.0 1.6 2 0 0 2 2 2 1 TrkA-N domain AAA PF00004.29 KKK12927.1 - 3.6e-43 147.1 0.0 1.1e-42 145.6 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) FtsH_ext PF06480.15 KKK12927.1 - 1.9e-12 47.5 0.1 4.4e-12 46.3 0.1 1.7 1 0 0 1 1 1 1 FtsH Extracellular AAA_lid_3 PF17862.1 KKK12927.1 - 1.7e-06 27.7 0.2 5.1e-06 26.2 0.2 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 KKK12927.1 - 0.00012 22.1 0.0 0.0004 20.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KKK12927.1 - 0.0023 18.3 0.2 0.16 12.3 0.2 2.7 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KKK12927.1 - 0.0024 18.2 0.0 0.78 10.0 0.1 3.1 3 0 0 3 3 3 1 AAA domain TIP49 PF06068.13 KKK12927.1 - 0.0073 15.6 0.1 0.013 14.8 0.1 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain RuvB_N PF05496.12 KKK12927.1 - 0.0074 16.0 0.0 0.022 14.5 0.0 1.8 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Serinc PF03348.15 KKK12927.1 - 0.014 14.4 0.1 0.019 13.9 0.1 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) AAA_2 PF07724.14 KKK12927.1 - 0.033 14.3 0.0 0.12 12.5 0.0 1.9 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_17 PF13207.6 KKK12927.1 - 0.065 13.7 0.2 0.27 11.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUF935 PF06074.12 KKK12927.1 - 0.078 11.7 1.3 0.087 11.6 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF935) IstB_IS21 PF01695.17 KKK12927.1 - 0.087 12.6 0.1 0.21 11.3 0.1 1.6 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA_11 PF13086.6 KKK12927.1 - 0.11 12.2 4.3 5 6.8 0.8 2.2 2 0 0 2 2 2 0 AAA domain UBN_AB PF14075.6 KKK12927.1 - 2.4 7.8 4.9 6.3 6.5 4.9 1.6 1 1 0 1 1 1 0 Ubinuclein conserved middle domain fn3 PF00041.21 KKK12934.1 - 3.5e-06 27.2 0.0 9.8e-06 25.8 0.0 1.8 1 0 0 1 1 1 1 Fibronectin type III domain LNS2 PF08235.13 KKK12935.1 - 4.6e-96 320.6 0.0 6.2e-96 320.2 0.0 1.2 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 KKK12935.1 - 7.8e-43 144.6 0.0 1.7e-42 143.5 0.0 1.6 2 0 0 2 2 2 1 lipin, N-terminal conserved region Acid_phosphat_B PF03767.14 KKK12935.1 - 0.0027 17.3 0.0 0.26 10.9 0.0 2.8 3 0 0 3 3 3 1 HAD superfamily, subfamily IIIB (Acid phosphatase) WRNPLPNID PF15017.6 KKK12935.1 - 1.1 10.2 9.6 3.1 8.7 9.6 1.9 1 0 0 1 1 1 0 Putative WW-binding domain and destruction box Thg1C PF14413.6 KKK12936.1 - 3.2e-53 179.0 1.3 4.2e-53 178.7 1.3 1.2 1 0 0 1 1 1 1 Thg1 C terminal domain Thg1 PF04446.12 KKK12936.1 - 2.8e-37 127.6 0.1 2.4e-36 124.5 0.1 2.4 1 1 0 1 1 1 1 tRNAHis guanylyltransferase Di19_C PF14571.6 KKK12936.1 - 0.24 11.9 1.9 1.3 9.6 0.1 2.3 2 0 0 2 2 2 0 Stress-induced protein Di19, C-terminal PcfK PF14058.6 KKK12937.1 - 0.021 15.1 4.5 0.021 15.1 4.5 2.2 2 0 0 2 2 2 0 PcfK-like protein FAM110_C PF14160.6 KKK12937.1 - 0.029 15.4 0.6 0.029 15.4 0.6 2.3 1 1 0 2 2 2 0 Centrosome-associated C terminus HSP70 PF00012.20 KKK12939.1 - 0.096 10.9 0.0 0.14 10.3 0.0 1.1 1 0 0 1 1 1 0 Hsp70 protein IF4E PF01652.18 KKK12941.1 - 1.9e-52 177.3 0.0 2.3e-52 177.0 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E RIIa PF02197.17 KKK12941.1 - 0.08 12.6 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Regulatory subunit of type II PKA R-subunit p450 PF00067.22 KKK12942.1 - 3.1e-42 144.9 0.0 5.4e-42 144.1 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 Ribosomal_S5 PF00333.20 KKK12943.1 - 1.6e-26 92.0 1.9 3.2e-26 91.1 1.0 1.9 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 KKK12943.1 - 1.5e-22 78.8 0.0 2.6e-22 78.1 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain PRR20 PF15708.5 KKK12943.1 - 0.04 13.8 4.8 0.072 13.0 4.8 1.3 1 0 0 1 1 1 0 Proline-rich protein family 20 Phage_tail_NK PF16532.5 KKK12943.1 - 0.082 12.5 0.1 0.12 11.9 0.1 1.2 1 0 0 1 1 1 0 Sf6-type phage tail needle knob or tip of some Caudovirales DUF5549 PF17703.1 KKK12943.1 - 0.47 10.1 3.8 0.82 9.3 3.8 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5549) FoP_duplication PF13865.6 KKK12943.1 - 0.76 10.4 13.3 1.7 9.2 13.3 1.6 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Mpv17_PMP22 PF04117.12 KKK12944.1 - 4.8e-23 81.2 1.0 8.6e-23 80.3 1.0 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family Peptidase_C12 PF01088.21 KKK12956.1 - 6.1e-64 215.6 0.0 7.7e-64 215.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 KKK12956.1 - 2.5e-09 36.9 0.0 6.7e-09 35.5 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolases Kei1 PF08552.11 KKK12956.1 - 0.1 12.4 0.1 0.16 11.8 0.1 1.2 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 DUF5421 PF17458.2 KKK12956.1 - 0.14 11.5 0.7 0.3 10.4 0.7 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5421) Choline_kinase PF01633.20 KKK12957.1 - 7.5e-60 202.1 0.0 2.3e-59 200.5 0.0 1.8 2 0 0 2 2 2 1 Choline/ethanolamine kinase Choline_kin_N PF04428.14 KKK12957.1 - 1.1e-16 60.2 0.0 2.8e-16 58.9 0.0 1.7 1 0 0 1 1 1 1 Choline kinase N terminus APH PF01636.23 KKK12957.1 - 1.2e-05 25.3 0.4 3.3e-05 23.9 0.4 1.8 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.25 KKK12958.1 - 1.2e-54 185.5 0.0 9.1e-52 176.0 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KKK12958.1 - 3.6e-31 108.4 0.0 2.1e-30 105.9 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Seadorna_VP7 PF07387.11 KKK12958.1 - 0.0043 16.1 0.1 0.0083 15.2 0.1 1.4 1 0 0 1 1 1 1 Seadornavirus VP7 Kinase-like PF14531.6 KKK12958.1 - 0.011 15.1 0.0 0.017 14.5 0.0 1.1 1 0 0 1 1 1 0 Kinase-like Pkinase_fungal PF17667.1 KKK12958.1 - 0.017 13.9 0.0 0.026 13.3 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 KKK12958.1 - 0.12 11.3 0.0 0.16 10.9 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Pyr_redox_2 PF07992.14 KKK12959.1 - 4.2e-56 190.3 0.3 4.8e-56 190.2 0.3 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KKK12959.1 - 6.9e-14 52.2 0.5 1.5e-13 51.1 0.5 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KKK12959.1 - 1.7e-12 47.2 0.6 1.1e-11 44.6 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KKK12959.1 - 4.8e-05 22.7 0.0 6.1e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) 3HCDH_N PF02737.18 KKK12959.1 - 0.00017 21.5 0.5 0.00029 20.8 0.5 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.22 KKK12959.1 - 0.5 9.4 5.8 1.5 7.8 0.5 2.7 3 1 0 3 3 3 0 Glucose inhibited division protein A Zn_clus PF00172.18 KKK12960.1 - 6.7e-08 32.5 13.2 6.7e-08 32.5 13.2 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KKK12960.1 - 0.0026 16.6 1.1 0.0039 16.1 1.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain TPR_15 PF13429.6 KKK12960.1 - 0.11 11.7 0.2 0.26 10.4 0.0 1.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Mem_trans PF03547.18 KKK12961.1 - 7e-56 189.3 0.1 9.6e-56 188.8 0.1 1.2 1 0 0 1 1 1 1 Membrane transport protein adh_short_C2 PF13561.6 KKK12962.1 - 2.9e-57 193.9 0.1 3.4e-57 193.7 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KKK12962.1 - 8.6e-46 155.9 0.5 1.1e-45 155.5 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KKK12962.1 - 2.7e-12 47.0 0.2 3.9e-12 46.4 0.2 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KKK12962.1 - 0.00024 20.7 0.1 0.00034 20.2 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Alk_phosphatase PF00245.20 KKK12962.1 - 0.055 12.4 0.0 0.077 11.9 0.0 1.1 1 0 0 1 1 1 0 Alkaline phosphatase GDP_Man_Dehyd PF16363.5 KKK12962.1 - 0.12 11.8 0.0 0.3 10.4 0.0 1.7 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase BIR PF00653.21 KKK12967.1 - 1.4e-45 153.8 6.9 1.4e-23 83.3 0.1 2.5 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain Tam41_Mmp37 PF09139.11 KKK12968.1 - 1.8e-128 428.6 0.0 2.1e-128 428.3 0.0 1.1 1 0 0 1 1 1 1 Phosphatidate cytidylyltransferase, mitochondrial TP_methylase PF00590.20 KKK12969.1 - 1e-24 87.7 0.1 1.8e-24 86.9 0.1 1.4 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases TFIID-18kDa PF02269.16 KKK12970.1 - 1.9e-29 101.5 0.3 3.2e-28 97.6 0.1 2.3 2 0 0 2 2 2 1 Transcription initiation factor IID, 18kD subunit TAFII28 PF04719.14 KKK12970.1 - 0.021 14.9 0.0 0.046 13.8 0.0 1.7 1 0 0 1 1 1 0 hTAFII28-like protein conserved region F-box PF00646.33 KKK12971.1 - 3.6e-05 23.5 1.2 0.0001 22.1 0.0 2.1 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KKK12971.1 - 5.5e-05 23.0 0.0 0.00011 22.0 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box-like_2 PF13013.6 KKK12971.1 - 0.091 12.7 0.3 0.14 12.2 0.3 1.4 1 1 0 1 1 1 0 F-box-like domain zf-C2H2_jaz PF12171.8 KKK12972.1 - 8.2e-09 35.5 0.1 1.4e-08 34.8 0.1 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KKK12972.1 - 5e-06 26.7 0.1 8.6e-06 26.0 0.1 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 KKK12972.1 - 0.00075 19.8 0.4 0.0014 19.0 0.4 1.5 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_2 PF12756.7 KKK12972.1 - 0.048 14.0 0.3 0.28 11.5 0.0 2.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 KKK12972.1 - 0.063 14.1 1.0 0.087 13.7 0.1 1.8 2 0 0 2 2 2 0 C2H2-type zinc finger FOXP-CC PF16159.5 KKK12972.1 - 0.18 12.4 1.0 0.44 11.2 0.5 1.9 1 1 1 2 2 2 0 FOXP coiled-coil domain DUF1168 PF06658.12 KKK12972.1 - 1.9 8.3 21.8 5.8 6.7 15.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1168) DUF3340 PF11818.8 KKK12972.1 - 4 7.6 17.4 5.2 7.2 10.1 2.2 2 0 0 2 2 2 0 C-terminal domain of tail specific protease (DUF3340) Sulfotransfer_4 PF17784.1 KKK12973.1 - 4.8e-74 248.8 0.0 5.9e-74 248.5 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KKK12973.1 - 2.2e-05 24.9 0.1 0.0022 18.4 0.1 2.4 1 1 1 2 2 2 2 Sulfotransferase family Arylsulfotran_2 PF14269.6 KKK12974.1 - 1.4e-54 185.6 6.7 2.1e-54 184.9 6.7 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 KKK12974.1 - 1.4e-20 73.6 5.6 3.8e-19 68.8 5.6 2.2 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) TMEM252 PF15664.5 KKK12974.1 - 0.037 13.7 0.4 0.27 11.0 0.1 2.2 2 0 0 2 2 2 0 Transmembrane protein 252 family Clat_adaptor_s PF01217.20 KKK12976.1 - 7.1e-51 171.9 3.0 4.4e-50 169.3 3.0 1.8 1 1 0 1 1 1 1 Clathrin adaptor complex small chain LRR_9 PF14580.6 KKK13028.1 - 2.1e-59 199.9 0.2 2.1e-59 199.9 0.2 1.5 2 0 0 2 2 2 1 Leucine-rich repeat LRR_8 PF13855.6 KKK13028.1 - 6.1e-05 22.7 1.6 0.00019 21.1 1.6 1.9 1 0 0 1 1 1 1 Leucine rich repeat LRR_4 PF12799.7 KKK13028.1 - 0.00062 20.1 4.8 0.19 12.2 0.1 3.2 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) DUF4349 PF14257.6 KKK13028.1 - 0.006 16.0 1.4 0.011 15.1 1.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4349) GDA1_CD39 PF01150.17 KKK13029.1 - 6.3e-98 328.2 0.0 2.4e-50 171.5 0.0 2.1 2 0 0 2 2 2 2 GDA1/CD39 (nucleoside phosphatase) family Ammonium_transp PF00909.21 KKK13030.1 - 6.5e-107 357.7 23.2 8.3e-107 357.3 23.2 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family MFS_1 PF07690.16 KKK13031.1 - 1.6e-28 99.7 34.0 3.6e-17 62.3 27.1 2.5 2 1 1 3 3 3 2 Major Facilitator Superfamily Acyltransferase PF01553.21 KKK13032.1 - 1e-17 64.0 0.0 2e-17 63.1 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase Pantoate_ligase PF02569.15 KKK13033.1 - 3.7e-91 305.0 0.0 5.2e-91 304.6 0.0 1.2 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase DEAD PF00270.29 KKK13034.1 - 3.1e-42 144.3 0.0 4.8e-42 143.7 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KKK13034.1 - 1.6e-20 73.5 0.0 4.5e-20 72.1 0.0 1.9 1 1 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 KKK13034.1 - 5.2e-20 71.4 0.0 1e-19 70.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 KKK13034.1 - 1.8e-06 28.1 0.0 4.1e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KKK13034.1 - 0.01 15.1 0.0 0.022 14.0 0.0 1.5 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase Fungal_trans_2 PF11951.8 KKK13035.1 - 1.7e-07 30.4 0.2 3.1e-07 29.6 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK13035.1 - 2.5e-05 24.3 10.9 5.2e-05 23.3 10.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WD40 PF00400.32 KKK13035.1 - 0.00023 21.9 3.9 0.061 14.2 0.1 5.2 4 0 0 4 4 4 1 WD domain, G-beta repeat PAXNEB PF05625.11 KKK13036.1 - 2.8e-117 392.0 0.0 3.2e-117 391.8 0.0 1.0 1 0 0 1 1 1 1 PAXNEB protein TMEM119 PF15724.5 KKK13036.1 - 0.4 10.7 5.4 0.46 10.5 2.7 2.0 2 0 0 2 2 2 0 TMEM119 family RNA_pol_Rpb8 PF03870.15 KKK13037.1 - 1.5e-45 154.8 0.0 1.7e-45 154.6 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 RNA_pol_RpbG PF16992.5 KKK13037.1 - 0.0047 17.0 0.0 1.3 9.1 0.0 2.1 2 0 0 2 2 2 2 DNA-directed RNA polymerase, subunit G DUF4743 PF15916.5 KKK13038.1 - 1.3e-15 57.4 0.0 2e-15 56.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4743) NUDIX PF00293.28 KKK13038.1 - 4.1e-13 49.5 0.0 7e-13 48.8 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain DUF775 PF05603.12 KKK13039.1 - 9.1e-66 221.2 0.0 1e-65 221.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF775) DZR PF12773.7 KKK13040.1 - 0.2 11.7 31.4 12 6.0 14.3 3.9 2 2 0 2 2 2 0 Double zinc ribbon FYVE_2 PF02318.16 KKK13040.1 - 3.5 7.9 21.3 0.57 10.4 2.7 3.3 3 0 0 3 3 3 0 FYVE-type zinc finger Zn_ribbon_17 PF17120.5 KKK13040.1 - 4.8 6.9 33.2 0.082 12.6 7.2 3.2 3 0 0 3 3 3 0 Zinc-ribbon, C4HC2 type SNF2_N PF00176.23 KKK13041.1 - 6.7e-56 189.5 0.2 1.1e-55 188.8 0.2 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KKK13041.1 - 1.8e-13 50.8 0.0 7e-11 42.5 0.0 2.5 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.15 KKK13041.1 - 4.9e-09 36.4 0.0 1.1e-08 35.2 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 KKK13041.1 - 0.0011 18.1 0.0 0.002 17.3 0.0 1.3 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ERCC3_RAD25_C PF16203.5 KKK13041.1 - 0.049 12.8 0.0 0.1 11.8 0.0 1.4 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase PHD PF00628.29 KKK13041.1 - 0.16 11.9 16.6 0.57 10.1 9.0 2.6 1 1 1 2 2 2 0 PHD-finger UPF0086 PF01868.16 KKK13042.1 - 3e-33 113.6 0.1 6.3e-33 112.5 0.1 1.5 2 0 0 2 2 2 1 Domain of unknown function UPF0086 Cucumopine_C PF18631.1 KKK13042.1 - 0.18 11.8 0.0 0.28 11.1 0.0 1.2 1 0 0 1 1 1 0 Cucumopine synthase C-terminal helical bundle domain tRNA_int_endo PF01974.17 KKK13043.1 - 1.5e-14 53.8 0.0 2.9e-14 52.9 0.0 1.4 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain Autophagy_N PF03986.13 KKK13043.1 - 0.17 11.8 3.3 0.28 11.1 3.3 1.2 1 0 0 1 1 1 0 Autophagocytosis associated protein (Atg3), N-terminal domain ATP-synt_E PF05680.12 KKK13043.1 - 5.5 7.4 9.1 6.3 7.2 8.2 1.5 1 1 0 1 1 1 0 ATP synthase E chain GATase PF00117.28 KKK13044.1 - 2.1e-12 47.2 0.0 2.9e-12 46.7 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 KKK13044.1 - 0.036 13.8 0.6 1.2 8.9 0.6 2.8 1 1 0 1 1 1 0 Peptidase C26 GATase_3 PF07685.14 KKK13044.1 - 0.15 11.6 0.0 0.27 10.8 0.0 1.4 1 1 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain MFS_1 PF07690.16 KKK13045.1 - 7.7e-43 146.8 36.5 7.7e-43 146.8 36.5 1.8 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KKK13045.1 - 5.5e-10 38.7 14.6 5.5e-10 38.7 14.6 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KKK13045.1 - 3.6e-07 29.0 19.2 5.4e-07 28.4 19.2 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Ribosomal_L22 PF00237.19 KKK13046.1 - 5e-28 97.4 0.2 1e-27 96.4 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein L22p/L17e Pectate_lyase_3 PF12708.7 KKK13047.1 - 2e-101 338.3 13.8 1.4e-87 293.0 10.4 2.5 2 0 0 2 2 2 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 KKK13047.1 - 1.1e-06 28.2 1.3 0.031 14.0 0.2 2.9 3 0 0 3 3 3 2 N terminal extension of bacteriophage endosialidase NosD PF05048.13 KKK13047.1 - 0.002 17.4 1.3 0.0045 16.3 1.3 1.5 1 0 0 1 1 1 1 Periplasmic copper-binding protein (NosD) Aminotran_1_2 PF00155.21 KKK13048.1 - 3.2e-17 62.8 0.0 3.9e-17 62.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II GAT PF03127.14 KKK13049.1 - 2.1e-18 66.4 0.1 4.2e-18 65.4 0.1 1.5 1 0 0 1 1 1 1 GAT domain HAUS6_N PF14661.6 KKK13049.1 - 0.38 10.3 5.2 0.2 11.2 1.1 2.1 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus LPMO_10 PF03067.15 KKK13050.1 - 2.7e-12 47.8 0.3 2.7e-12 47.8 0.3 2.1 2 0 0 2 2 2 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading GREB1 PF15782.5 KKK13050.1 - 7.2 3.6 10.1 8.7 3.3 10.1 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Transket_pyr PF02779.24 KKK13052.1 - 2.2e-64 216.4 0.0 4.3e-64 215.5 0.0 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.20 KKK13052.1 - 2.5e-59 200.7 0.0 3.7e-59 200.1 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component OxoGdeHyase_C PF16870.5 KKK13052.1 - 1.1e-57 194.1 0.0 1.7e-57 193.4 0.0 1.3 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal 2-oxogl_dehyd_N PF16078.5 KKK13052.1 - 8.4e-20 70.1 0.4 8.4e-20 70.1 0.4 2.0 2 0 0 2 2 2 1 2-oxoglutarate dehydrogenase N-terminus Cnn_1N PF07989.11 KKK13053.1 - 1.5e-09 37.8 10.3 3.5e-09 36.7 10.3 1.6 1 0 0 1 1 1 1 Centrosomin N-terminal motif 1 AAA_23 PF13476.6 KKK13053.1 - 0.025 15.1 11.4 0.052 14.1 11.2 1.6 2 0 0 2 2 2 0 AAA domain YabA PF06156.13 KKK13053.1 - 0.39 11.4 7.8 0.97 10.1 7.4 1.9 1 1 0 1 1 1 0 Initiation control protein YabA FlaC_arch PF05377.11 KKK13053.1 - 1.6 9.2 6.2 2.1 8.8 4.3 2.2 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF3584 PF12128.8 KKK13053.1 - 4 4.8 17.2 5.6 4.4 17.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) PKcGMP_CC PF16808.5 KKK13053.1 - 5.9 6.8 10.4 0.71 9.8 5.6 2.0 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Sld5 PF05916.11 KKK13055.1 - 1.2e-20 74.0 0.0 1.5e-20 73.7 0.0 1.1 1 0 0 1 1 1 1 GINS complex protein tRNA-synt_2 PF00152.20 KKK13058.1 - 1.8e-65 221.1 0.0 2.5e-65 220.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) DUF2156 PF09924.9 KKK13058.1 - 1.4e-11 44.0 0.0 2e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2156) tRNA-synt_2d PF01409.20 KKK13058.1 - 0.0034 16.9 0.3 0.11 11.9 0.0 2.5 3 0 0 3 3 3 1 tRNA synthetases class II core domain (F) tRNA_anti-codon PF01336.25 KKK13058.1 - 0.0037 17.2 0.0 0.0074 16.3 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain MCM_N PF14551.6 KKK13058.1 - 0.065 13.8 0.0 0.15 12.7 0.0 1.6 1 0 0 1 1 1 0 MCM N-terminal domain Pyr_redox_2 PF07992.14 KKK13059.1 - 5.6e-45 153.8 0.2 7.6e-45 153.4 0.2 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KKK13059.1 - 1.3e-18 67.3 1.3 2.3e-14 53.7 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Rhodanese PF00581.20 KKK13059.1 - 1.1e-09 38.7 0.0 2.3e-08 34.5 0.0 2.7 3 0 0 3 3 3 1 Rhodanese-like domain FAD_binding_2 PF00890.24 KKK13059.1 - 1.8e-07 30.6 2.0 0.0005 19.3 0.0 2.9 3 0 0 3 3 3 2 FAD binding domain NAD_binding_8 PF13450.6 KKK13059.1 - 1.1e-06 28.8 4.9 0.012 15.8 0.5 3.1 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.21 KKK13059.1 - 4.3e-06 26.2 3.4 0.0093 15.3 0.2 2.7 3 0 0 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.24 KKK13059.1 - 6e-06 26.1 3.2 0.017 14.7 0.0 3.1 3 0 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KKK13059.1 - 8.1e-06 25.3 3.4 0.12 11.6 0.7 3.1 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 KKK13059.1 - 5.4e-05 23.4 0.0 0.00021 21.5 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain TrkA_N PF02254.18 KKK13059.1 - 0.00026 21.3 0.7 0.0018 18.5 0.0 2.2 2 0 0 2 2 2 1 TrkA-N domain HI0933_like PF03486.14 KKK13059.1 - 0.00051 18.9 8.8 0.12 11.0 0.4 3.4 2 1 1 3 3 3 2 HI0933-like protein Lycopene_cycl PF05834.12 KKK13059.1 - 0.00098 18.3 7.7 0.22 10.6 0.3 3.3 2 1 1 3 3 3 2 Lycopene cyclase protein NAD_binding_7 PF13241.6 KKK13059.1 - 0.0023 18.3 1.4 0.49 10.9 0.0 2.5 1 1 1 2 2 2 1 Putative NAD(P)-binding 3HCDH_N PF02737.18 KKK13059.1 - 0.005 16.7 0.0 0.0099 15.8 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 KKK13059.1 - 0.01 15.2 0.0 0.022 14.1 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GIDA PF01134.22 KKK13059.1 - 0.032 13.3 1.8 1.8 7.6 0.4 2.3 2 0 0 2 2 2 0 Glucose inhibited division protein A XdhC_C PF13478.6 KKK13059.1 - 0.033 14.7 0.0 0.57 10.7 0.0 2.3 2 0 0 2 2 2 0 XdhC Rossmann domain FAD_oxidored PF12831.7 KKK13059.1 - 0.064 12.6 10.2 0.085 12.2 1.9 2.4 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KKK13059.1 - 0.12 11.6 0.1 0.12 11.6 0.1 1.9 2 0 0 2 2 2 0 FAD binding domain Thi4 PF01946.17 KKK13059.1 - 0.17 11.1 1.2 4.1 6.6 0.1 2.3 2 0 0 2 2 2 0 Thi4 family Trp_halogenase PF04820.14 KKK13059.1 - 1 8.1 5.1 1.5 7.5 0.6 2.1 2 0 0 2 2 2 0 Tryptophan halogenase Helo_like_N PF17111.5 KKK13060.1 - 0.11 11.8 0.0 0.24 10.8 0.0 1.6 1 0 0 1 1 1 0 Fungal N-terminal domain of STAND proteins Zona_pellucida PF00100.23 KKK13061.1 - 0.062 13.1 0.1 0.12 12.1 0.1 1.5 1 1 0 1 1 1 0 Zona pellucida-like domain AhpC-TSA PF00578.21 KKK13063.1 - 2.2e-29 101.9 0.0 3e-29 101.5 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family 1-cysPrx_C PF10417.9 KKK13063.1 - 8e-14 51.2 0.1 1.3e-13 50.5 0.1 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Redoxin PF08534.10 KKK13063.1 - 9.5e-13 48.1 0.0 1.2e-12 47.8 0.0 1.1 1 0 0 1 1 1 1 Redoxin AMP-binding PF00501.28 KKK13064.1 - 4.4e-73 246.3 0.1 6.3e-73 245.8 0.1 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 KKK13064.1 - 8.3e-55 186.3 0.0 1.1e-54 185.8 0.0 1.1 1 0 0 1 1 1 1 Condensation domain NAD_binding_4 PF07993.12 KKK13064.1 - 7.2e-27 94.2 0.0 3.7e-23 82.0 0.0 3.2 1 1 0 1 1 1 1 Male sterility protein PP-binding PF00550.25 KKK13064.1 - 3.3e-14 53.0 0.1 7.3e-14 51.9 0.1 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.21 KKK13064.1 - 0.00021 20.9 0.0 0.00082 18.9 0.0 1.9 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KKK13064.1 - 0.0083 15.2 0.0 0.014 14.4 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family FliP PF00813.20 KKK13065.1 - 0.1 12.4 2.5 1.7 8.5 1.3 2.2 1 1 0 2 2 2 0 FliP family CCSMST1 PF15013.6 KKK13065.1 - 0.74 10.0 2.1 0.77 10.0 0.8 1.7 1 1 1 2 2 2 0 CCSMST1 family ABC2_membrane PF01061.24 KKK13065.1 - 3.9 6.8 11.2 0.14 11.6 1.4 2.4 1 1 0 2 2 2 0 ABC-2 type transporter Hydantoinase_B PF02538.14 KKK13066.1 - 1.2e-218 726.7 0.5 1.6e-218 726.3 0.5 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 KKK13066.1 - 8.4e-101 337.1 0.1 1.3e-99 333.1 0.0 2.1 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 KKK13066.1 - 3e-56 189.9 0.0 2.1e-53 180.7 0.0 2.5 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region Kdo PF06293.14 KKK13067.1 - 4.9e-05 22.8 0.1 9.2e-05 21.9 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KKK13067.1 - 0.00057 19.9 6.8 0.002 18.1 0.5 2.9 2 1 1 3 3 3 2 Phosphotransferase enzyme family Choline_kinase PF01633.20 KKK13067.1 - 0.015 14.9 0.0 0.037 13.6 0.0 1.6 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF2828 PF11443.8 KKK13067.1 - 0.049 11.7 0.0 0.076 11.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Pkinase PF00069.25 KKK13067.1 - 0.19 11.1 0.3 0.52 9.6 0.0 1.8 2 0 0 2 2 2 0 Protein kinase domain DUF3523 PF12037.8 KKK13067.1 - 0.83 9.0 11.6 1.5 8.1 11.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3523) HECT PF00632.25 KKK13068.1 - 9.1e-84 281.5 0.0 1.4e-83 280.9 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) IQ PF00612.27 KKK13068.1 - 0.068 13.0 1.7 0.25 11.3 1.7 2.0 1 0 0 1 1 1 0 IQ calmodulin-binding motif Glyco_hydro_71 PF03659.14 KKK13070.1 - 9.4e-137 455.8 5.2 9.4e-137 455.8 5.2 1.6 2 0 0 2 2 2 1 Glycosyl hydrolase family 71 MATalpha_HMGbox PF04769.12 KKK13071.1 - 3.5e-38 130.9 0.0 4.9e-38 130.5 0.0 1.3 1 0 0 1 1 1 1 Mating-type protein MAT alpha 1 HMG-box Hexapep PF00132.24 KKK13072.1 - 1.8e-09 37.0 13.8 0.005 16.5 0.8 4.4 3 1 2 5 5 5 5 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KKK13072.1 - 1.8e-07 30.8 5.6 0.00083 19.1 0.9 3.3 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase gerPA PF10676.9 KKK13072.1 - 0.018 15.3 1.3 0.65 10.3 0.2 2.4 2 0 0 2 2 2 0 Spore germination protein gerPA/gerPF Pkinase PF00069.25 KKK13073.1 - 1.7e-52 178.4 0.0 4.9e-34 117.9 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KKK13073.1 - 1.3e-25 90.1 0.0 3.8e-24 85.4 0.0 3.0 2 1 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 KKK13073.1 - 7.3e-05 22.8 1.9 0.00038 20.4 0.1 2.5 3 0 0 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KKK13073.1 - 0.00059 19.2 0.0 0.0025 17.2 0.0 1.9 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KKK13073.1 - 0.0012 17.7 0.6 0.0043 15.9 0.0 2.1 2 0 0 2 2 2 1 Fungal protein kinase SEP PF08059.13 KKK13075.1 - 6.5e-26 90.7 0.1 1.4e-25 89.7 0.1 1.6 1 0 0 1 1 1 1 SEP domain UBX PF00789.20 KKK13075.1 - 8.6e-15 54.7 0.0 1.4e-14 54.0 0.0 1.4 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.6 KKK13075.1 - 3.5e-13 49.1 1.7 6.3e-13 48.3 1.7 1.4 1 0 0 1 1 1 1 UBA-like domain TAP_C PF03943.13 KKK13075.1 - 0.00025 20.6 0.1 0.00048 19.7 0.1 1.4 1 0 0 1 1 1 1 TAP C-terminal domain ParA PF10609.9 KKK13076.1 - 4e-72 242.6 5.9 7.6e-45 153.3 0.5 2.9 1 1 1 2 2 2 2 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 KKK13076.1 - 1.8e-08 34.5 0.0 2.3e-08 34.1 0.0 1.3 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.11 KKK13076.1 - 3.6e-07 29.8 0.0 3.3e-06 26.6 0.0 2.0 2 0 0 2 2 2 1 ATPase MipZ AAA_31 PF13614.6 KKK13076.1 - 2e-05 24.6 0.3 0.00024 21.1 0.3 2.1 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KKK13076.1 - 0.00049 19.7 0.2 0.00088 18.9 0.2 1.4 1 0 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.15 KKK13076.1 - 0.0011 18.2 1.3 0.0016 17.7 0.7 1.4 2 0 0 2 2 2 1 Anion-transporting ATPase CBP_BcsQ PF06564.12 KKK13076.1 - 0.006 16.1 0.5 0.052 13.0 0.2 2.1 2 0 0 2 2 2 1 Cellulose biosynthesis protein BcsQ MeaB PF03308.16 KKK13076.1 - 0.014 14.4 0.5 0.014 14.4 0.5 1.4 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB APS_kinase PF01583.20 KKK13076.1 - 0.064 13.1 0.1 0.099 12.5 0.1 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase Fer4_NifH PF00142.18 KKK13076.1 - 0.11 11.9 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.22 KKK13076.1 - 0.11 12.1 0.5 2.3 7.8 0.3 2.1 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_26 PF13500.6 KKK13076.1 - 0.14 11.9 1.4 4.1 7.2 0.7 2.2 2 0 0 2 2 2 0 AAA domain COG2 PF06148.11 KKK13077.1 - 3e-38 130.9 3.3 3e-38 130.9 3.3 1.7 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 COG5 PF10392.9 KKK13077.1 - 1.2e-05 25.5 1.5 1.2e-05 25.5 1.5 2.1 2 0 0 2 2 2 1 Golgi transport complex subunit 5 Vps51 PF08700.11 KKK13077.1 - 2.3e-05 24.4 2.5 0.00019 21.5 2.5 2.5 1 1 0 1 1 1 1 Vps51/Vps67 Vps54_N PF10475.9 KKK13077.1 - 0.0059 15.9 0.1 0.011 15.1 0.1 1.4 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex Bul1_C PF04426.12 KKK13077.1 - 0.054 12.9 0.3 0.11 11.9 0.1 1.5 1 1 0 1 1 1 0 Bul1 C terminus STAR_dimer PF16544.5 KKK13077.1 - 0.086 12.4 2.2 7.6 6.2 0.4 2.5 2 0 0 2 2 2 0 Homodimerisation region of STAR domain protein Sec34 PF04136.15 KKK13077.1 - 0.19 11.6 2.7 0.35 10.8 0.2 2.3 1 1 1 2 2 2 0 Sec34-like family Sec8_exocyst PF04048.14 KKK13077.1 - 0.24 11.3 2.6 0.26 11.2 0.4 2.1 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain Exonuc_VII_L PF02601.15 KKK13077.1 - 0.33 10.5 9.6 1 8.8 3.1 2.1 1 1 0 2 2 2 0 Exonuclease VII, large subunit Bcr-Abl_Oligo PF09036.10 KKK13077.1 - 0.53 10.3 0.0 0.53 10.3 0.0 2.5 3 0 0 3 3 3 0 Bcr-Abl oncoprotein oligomerisation domain PXA PF02194.15 KKK13077.1 - 0.55 10.2 2.6 1 9.3 2.6 1.6 1 1 0 1 1 1 0 PXA domain DUF1664 PF07889.12 KKK13077.1 - 0.87 9.6 3.6 0.61 10.1 1.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Spc7 PF08317.11 KKK13077.1 - 1.1 8.1 10.2 0.22 10.4 5.3 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein FlaC_arch PF05377.11 KKK13077.1 - 1.7 9.1 10.0 1.2 9.6 1.2 3.7 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) NPV_P10 PF05531.12 KKK13077.1 - 2 8.9 5.0 5.4 7.6 0.8 2.9 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein TolA_bind_tri PF16331.5 KKK13077.1 - 2.7 8.1 15.8 0.078 13.1 1.2 3.8 4 0 0 4 4 4 0 TolA binding protein trimerisation RasGEF PF00617.19 KKK13078.1 - 1.6e-50 171.8 0.3 3.5e-50 170.7 0.3 1.6 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 KKK13078.1 - 2.8e-15 56.4 0.0 9.1e-15 54.8 0.0 1.9 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_9 PF14604.6 KKK13078.1 - 1.3e-06 28.2 0.1 4.2e-06 26.5 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 KKK13078.1 - 1.2e-05 24.9 0.0 3.2e-05 23.4 0.0 1.8 1 0 0 1 1 1 1 SH3 domain Med16 PF11635.8 KKK13083.1 - 1.1e-200 668.3 0.0 1.3e-109 367.3 0.0 2.7 1 1 1 2 2 2 2 Mediator complex subunit 16 ANAPC4_WD40 PF12894.7 KKK13083.1 - 7.6e-06 26.2 0.1 0.1 12.9 0.0 3.4 3 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Ribosomal_L29 PF00831.23 KKK13084.1 - 5.9e-20 71.0 0.4 5.9e-20 71.0 0.4 1.9 2 0 0 2 2 2 1 Ribosomal L29 protein V-SNARE_C PF12352.8 KKK13085.1 - 1.7e-13 50.7 0.1 1.7e-13 50.7 0.1 3.0 4 0 0 4 4 4 1 Snare region anchored in the vesicle membrane C-terminus GOLGA2L5 PF15070.6 KKK13085.1 - 0.013 14.2 5.3 0.018 13.7 5.3 1.1 1 0 0 1 1 1 0 Putative golgin subfamily A member 2-like protein 5 Surfac_D-trimer PF09006.11 KKK13085.1 - 0.044 13.7 0.5 1.3 8.9 0.1 2.4 2 0 0 2 2 2 0 Lung surfactant protein D coiled-coil trimerisation TipAS PF07739.13 KKK13085.1 - 0.13 12.9 0.4 0.3 11.6 0.3 1.7 1 1 0 1 1 1 0 TipAS antibiotic-recognition domain PA28_beta PF02252.18 KKK13085.1 - 0.35 10.5 1.2 0.5 10.0 0.2 1.7 2 0 0 2 2 2 0 Proteasome activator pa28 beta subunit SATase_N PF06426.14 KKK13085.1 - 0.84 10.0 4.5 1.3 9.5 2.3 2.3 1 1 1 2 2 2 0 Serine acetyltransferase, N-terminal FUSC PF04632.12 KKK13085.1 - 3.5 6.0 6.2 4.1 5.8 6.2 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family CBFD_NFYB_HMF PF00808.23 KKK13086.1 - 2.8e-05 24.3 0.0 5.2e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KKK13086.1 - 0.38 11.1 5.1 0.4 11.0 0.0 2.4 2 0 0 2 2 2 0 Core histone H2A/H2B/H3/H4 SID-1_RNA_chan PF13965.6 KKK13086.1 - 0.49 8.8 0.9 0.52 8.6 0.9 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Presenilin PF01080.17 KKK13086.1 - 9.3 4.9 12.0 11 4.7 12.0 1.2 1 0 0 1 1 1 0 Presenilin SIR2 PF02146.17 KKK13087.1 - 8.2e-25 87.8 0.4 6.7e-24 84.8 0.0 2.5 2 1 0 2 2 2 1 Sir2 family ACP_PD PF04336.12 KKK13087.1 - 0.035 14.5 0.0 0.069 13.6 0.0 1.4 1 0 0 1 1 1 0 Acyl carrier protein phosphodiesterase Zn-ribbon_8 PF09723.10 KKK13087.1 - 0.77 9.9 4.5 0.69 10.1 1.8 2.3 3 0 0 3 3 3 0 Zinc ribbon domain Ter PF05472.11 KKK13088.1 - 0.013 14.6 0.0 0.016 14.2 0.0 1.1 1 0 0 1 1 1 0 DNA replication terminus site-binding protein (Ter protein) Glyco_hydro_7 PF00840.20 KKK13091.1 - 8.8e-204 677.1 14.9 1e-203 677.0 14.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Abhydrolase_1 PF00561.20 KKK13092.1 - 1.4e-13 51.1 0.2 1.2e-12 48.0 0.2 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KKK13092.1 - 3.6e-11 42.8 0.0 5.7e-10 38.9 0.0 2.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KKK13092.1 - 1.1e-10 42.5 0.3 2.3e-10 41.4 0.3 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.18 KKK13092.1 - 2.6e-05 23.9 0.5 1.8 8.1 0.0 3.2 3 0 0 3 3 3 3 Dienelactone hydrolase family FSH1 PF03959.13 KKK13092.1 - 0.0017 18.1 0.0 0.13 11.9 0.0 2.8 2 1 0 2 2 2 1 Serine hydrolase (FSH1) DUF2048 PF09752.9 KKK13092.1 - 0.024 13.8 0.3 0.09 11.9 0.5 1.7 2 0 0 2 2 2 0 Abhydrolase domain containing 18 BAAT_C PF08840.11 KKK13092.1 - 0.031 14.2 0.1 0.3 11.0 0.1 2.1 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal ANAPC4_WD40 PF12894.7 KKK13093.1 - 0.00025 21.3 0.0 1.4 9.2 0.0 3.0 2 1 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain RAB3GAP2_N PF14655.6 KKK13093.1 - 0.011 15.0 0.1 2.5 7.3 0.0 2.6 3 0 0 3 3 3 0 Rab3 GTPase-activating protein regulatory subunit N-terminus TFIIF_alpha PF05793.12 KKK13093.1 - 1.2 7.6 13.2 2.1 6.8 13.2 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) TLP-20 PF06088.11 KKK13093.1 - 1.6 8.6 4.6 0.35 10.7 1.3 1.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) CDC45 PF02724.14 KKK13093.1 - 2.6 6.2 9.0 4.1 5.6 9.0 1.2 1 0 0 1 1 1 0 CDC45-like protein FAD_binding_4 PF01565.23 KKK13100.1 - 0.011 15.5 0.1 0.019 14.7 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain eIF2A PF08662.11 KKK13101.1 - 1.6e-83 279.4 0.0 1.1e-82 276.7 0.1 2.1 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A WD40 PF00400.32 KKK13101.1 - 0.0087 16.9 0.8 6.2 7.9 0.0 4.4 4 0 0 4 4 4 1 WD domain, G-beta repeat DPPIV_N PF00930.21 KKK13101.1 - 0.059 12.1 0.0 3.3 6.4 0.0 2.4 2 0 0 2 2 2 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region CDV3 PF15359.6 KKK13101.1 - 0.18 12.3 3.8 0.5 10.8 0.2 2.6 2 0 0 2 2 2 0 Carnitine deficiency-associated protein 3 PD40 PF07676.12 KKK13101.1 - 0.31 11.0 2.2 12 6.0 0.1 4.0 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Glyco_transf_8 PF01501.20 KKK13102.1 - 6.9e-07 29.1 0.0 8.7e-07 28.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 8 ELO PF01151.18 KKK13115.1 - 2.7e-62 210.5 20.8 3.3e-62 210.3 20.8 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family SAC3_GANP PF03399.16 KKK13117.1 - 4.6e-26 91.9 0.8 3.9e-14 52.7 0.1 2.1 1 1 1 2 2 2 2 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 KKK13117.1 - 0.00041 20.3 0.0 0.001 19.1 0.0 1.6 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family TPR_MalT PF17874.1 KKK13117.1 - 0.015 14.7 0.2 0.026 13.9 0.2 1.2 1 0 0 1 1 1 0 MalT-like TPR region R3H-assoc PF13902.6 KKK13118.1 - 1.1e-20 74.4 6.8 4.7e-20 72.3 6.4 2.3 1 1 0 1 1 1 1 R3H-associated N-terminal domain R3H PF01424.22 KKK13118.1 - 0.0013 18.6 0.1 0.1 12.6 0.0 2.6 2 1 0 2 2 2 2 R3H domain Peptidase_M28 PF04389.17 KKK13119.1 - 6.3e-31 107.6 0.3 8.8e-31 107.1 0.3 1.2 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 KKK13119.1 - 1.9e-06 27.7 0.1 3.7e-06 26.8 0.1 1.6 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 PTAC PF06130.12 KKK13119.1 - 0.31 11.2 2.0 0.63 10.2 0.3 2.2 2 0 0 2 2 2 0 Phosphate propanoyltransferase Inositol_P PF00459.25 KKK13120.1 - 1.1e-38 133.4 0.1 3.7e-38 131.6 0.1 1.7 1 1 0 1 1 1 1 Inositol monophosphatase family Chitin_synth_1 PF01644.17 KKK13121.1 - 2.4e-78 261.7 0.1 3.7e-78 261.1 0.1 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 KKK13121.1 - 1.8e-28 98.2 0.2 3.8e-28 97.2 0.2 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 KKK13121.1 - 5.6e-21 74.8 0.3 8.8e-19 67.5 0.0 2.5 2 0 0 2 2 2 1 Chitin synthase Glyco_trans_2_3 PF13632.6 KKK13121.1 - 3.5e-07 30.3 0.7 1.1e-06 28.7 0.2 2.2 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KKK13121.1 - 0.03 14.2 0.0 0.14 12.1 0.0 2.1 2 1 1 3 3 3 0 Glycosyltransferase like family 2 YesK PF14150.6 KKK13121.1 - 8.9 6.6 8.7 0.92 9.7 3.7 2.0 2 0 0 2 2 2 0 YesK-like protein Hpt PF01627.23 KKK13123.1 - 6.9e-11 42.3 0.0 1.8e-10 40.9 0.0 1.7 2 0 0 2 2 2 1 Hpt domain Pkinase PF00069.25 KKK13124.1 - 3.5e-11 43.0 0.0 1.7e-08 34.1 0.0 2.4 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KKK13124.1 - 2.8e-07 30.1 0.0 1.2e-06 28.0 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 KKK13124.1 - 0.0016 17.8 0.0 0.0026 17.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like tRNA-synt_1b PF00579.25 KKK13125.1 - 2.7e-56 191.1 0.0 3.3e-56 190.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) RTC4 PF14474.6 KKK13125.1 - 0.022 14.9 0.0 0.067 13.4 0.0 1.9 2 0 0 2 2 2 0 RTC4-like domain HCMVantigenic_N PF12154.8 KKK13126.1 - 3 8.0 8.2 0.22 11.6 2.9 1.9 2 0 0 2 2 2 0 Glycoprotein B N-terminal antigenic domain of HCMV DUF1794 PF08768.11 KKK13127.1 - 0.06 13.3 0.1 0.082 12.9 0.1 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF1794) Ribonuc_L-PSP PF01042.21 KKK13127.1 - 0.1 12.6 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 Endoribonuclease L-PSP Glyco_hydro_72 PF03198.14 KKK13128.1 - 1.3e-100 336.8 0.1 1.7e-100 336.3 0.1 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Glyco_hydro_2_C PF02836.17 KKK13128.1 - 0.00079 18.6 0.0 0.0013 17.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Cellulase PF00150.18 KKK13128.1 - 0.0042 16.6 0.1 0.044 13.2 0.1 2.2 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Alpha-amylase PF00128.24 KKK13129.1 - 7e-117 390.7 0.1 1.1e-116 390.1 0.1 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Malt_amylase_C PF16657.5 KKK13129.1 - 6.6e-05 23.0 0.0 0.00012 22.1 0.0 1.5 1 0 0 1 1 1 1 Maltogenic Amylase, C-terminal domain hDGE_amylase PF14701.6 KKK13129.1 - 0.022 13.9 0.0 0.056 12.5 0.0 1.6 2 0 0 2 2 2 0 Glycogen debranching enzyme, glucanotransferase domain Glyco_hydro_114 PF03537.13 KKK13129.1 - 0.068 12.5 0.0 2.2 7.5 0.0 2.3 2 0 0 2 2 2 0 Glycoside-hydrolase family GH114 Mo-nitro_C PF06967.11 KKK13130.1 - 0.06 13.3 0.1 0.81 9.7 0.1 2.4 2 0 0 2 2 2 0 Mo-dependent nitrogenase C-terminus Sds3 PF08598.11 KKK13131.1 - 8.3e-48 163.3 0.0 3.8e-45 154.6 0.0 2.1 1 1 0 1 1 1 1 Sds3-like HAUS6_N PF14661.6 KKK13131.1 - 0.06 12.9 1.0 0.071 12.7 0.1 1.6 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus FAM184 PF15665.5 KKK13131.1 - 0.76 9.5 5.9 0.16 11.8 1.6 1.9 2 0 0 2 2 2 0 Family with sequence similarity 184, A and B Fungal_trans PF04082.18 KKK13132.1 - 2.7e-10 39.7 0.1 4.8e-10 38.9 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK13132.1 - 8.9e-07 28.9 10.8 2.4e-06 27.6 10.8 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Phage_rep_O PF04492.13 KKK13132.1 - 0.047 14.3 0.0 0.1 13.2 0.0 1.5 1 0 0 1 1 1 0 Bacteriophage replication protein O Glyco_hydro_43 PF04616.14 KKK13133.1 - 4.6e-35 121.3 0.2 6.3e-35 120.9 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 DOCK_N PF16172.5 KKK13141.1 - 5e-117 391.0 0.0 9.6e-117 390.1 0.0 1.5 1 0 0 1 1 1 1 DOCK N-terminus DOCK-C2 PF14429.6 KKK13141.1 - 1.8e-36 125.8 0.0 4.2e-36 124.6 0.0 1.7 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins DHR-2 PF06920.13 KKK13141.1 - 3.2e-35 121.8 1.6 1.1e-34 120.0 1.6 1.8 1 1 0 1 1 1 1 Dock homology region 2 SH3_1 PF00018.28 KKK13141.1 - 1.4e-05 24.6 0.0 2.9e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KKK13141.1 - 0.0001 22.1 0.0 0.00087 19.1 0.0 2.2 2 0 0 2 2 2 1 Variant SH3 domain DUF1737 PF08410.10 KKK13141.1 - 0.17 11.7 0.1 0.54 10.2 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1737) SRP40_C PF05022.12 KKK13142.1 - 1e-17 64.7 0.5 4.1e-17 62.8 0.5 2.1 1 0 0 1 1 1 1 SRP40, C-terminal domain DUF2653 PF10850.8 KKK13142.1 - 0.088 13.0 0.0 0.15 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2653) Sec3_C PF09763.9 KKK13143.1 - 2.2e-222 740.4 0.4 2.7e-222 740.0 0.4 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.6 KKK13143.1 - 3.9e-28 97.4 0.1 9.5e-28 96.2 0.1 1.7 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Sec3_C_2 PF15278.6 KKK13143.1 - 0.032 14.6 0.3 0.11 12.9 0.3 1.9 1 0 0 1 1 1 0 Sec3 exocyst complex subunit Vps52 PF04129.12 KKK13143.1 - 0.038 12.7 0.4 0.073 11.8 0.4 1.4 1 0 0 1 1 1 0 Vps52 / Sac2 family FUSC PF04632.12 KKK13143.1 - 0.4 9.2 3.6 0.69 8.4 3.6 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family CCDC-167 PF15188.6 KKK13143.1 - 4 7.9 5.2 11 6.4 2.6 2.7 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 F-box-like PF12937.7 KKK13144.1 - 0.00011 22.0 0.1 0.00033 20.5 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KKK13144.1 - 0.0006 19.6 0.1 0.0019 18.0 0.0 1.9 2 0 0 2 2 2 1 F-box domain p450 PF00067.22 KKK13145.1 - 8.3e-39 133.6 0.0 1.4e-38 132.8 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_18 PF00704.28 KKK13146.1 - 3.4e-23 82.8 0.5 1.1e-22 81.2 0.5 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 BDHCT_assoc PF16204.5 KKK13146.1 - 0.33 10.6 3.3 0.5 10.0 3.3 1.3 1 0 0 1 1 1 0 BDHCT-box associated domain on Bloom syndrome protein SSP160 PF06933.11 KKK13146.1 - 5.2 5.1 20.4 8.6 4.4 20.4 1.3 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Abhydrolase_3 PF07859.13 KKK13147.1 - 3.4e-66 223.1 0.1 4.4e-66 222.8 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KKK13147.1 - 3.7e-08 32.7 0.0 7.2e-08 31.7 0.0 1.4 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 KKK13147.1 - 3.1e-07 30.1 0.0 6e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Say1_Mug180 PF10340.9 KKK13147.1 - 0.0058 15.5 0.0 0.019 13.9 0.0 1.9 2 0 0 2 2 2 1 Steryl acetyl hydrolase PhzC-PhzF PF02567.16 KKK13147.1 - 0.16 11.4 0.0 0.28 10.6 0.0 1.3 1 0 0 1 1 1 0 Phenazine biosynthesis-like protein FTR1 PF03239.14 KKK13148.1 - 2.7e-91 306.0 1.5 2.7e-91 306.0 1.5 1.6 2 0 0 2 2 2 1 Iron permease FTR1 family PIG-F PF06699.11 KKK13148.1 - 0.65 10.1 9.5 0.99 9.5 3.2 2.7 2 0 0 2 2 2 0 GPI biosynthesis protein family Pig-F Cu-oxidase_2 PF07731.14 KKK13149.1 - 3e-44 150.1 8.4 1.8e-40 137.8 0.6 3.8 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 KKK13149.1 - 3.2e-41 140.1 10.4 8.1e-40 135.5 1.6 3.7 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 KKK13149.1 - 4.2e-37 127.7 6.2 1.4e-35 122.8 0.6 3.5 3 1 0 3 3 3 1 Multicopper oxidase DUF5060 PF16586.5 KKK13149.1 - 0.084 13.3 2.4 0.3 11.5 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF5060) SUR7 PF06687.12 KKK13149.1 - 1.2 8.7 5.7 6.9 6.2 0.2 2.3 2 0 0 2 2 2 0 SUR7/PalI family PhoD PF09423.10 KKK13150.1 - 2.4e-37 128.8 0.0 1.1e-36 126.6 0.0 2.0 1 1 0 1 1 1 1 PhoD-like phosphatase Glyco_hydro_18 PF00704.28 KKK13150.1 - 1.1e-11 45.1 0.0 1.9e-11 44.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Fez1 PF06818.15 KKK13151.1 - 0.0019 18.7 16.6 0.0019 18.7 16.6 5.0 1 1 3 4 4 4 2 Fez1 KASH_CCD PF14662.6 KKK13151.1 - 5.7 6.7 75.5 0.57 10.0 25.8 3.5 2 1 1 3 3 3 0 Coiled-coil region of CCDC155 or KASH SRF-TF PF00319.18 KKK13152.1 - 3.3e-21 74.5 0.1 5e-21 73.9 0.1 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Mg_trans_NIPA PF05653.14 KKK13153.1 - 3.4e-17 62.5 12.7 7e-09 35.2 2.3 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA PUNUT PF16913.5 KKK13153.1 - 1.1e-06 28.2 0.5 1.1e-06 28.2 0.5 2.0 2 0 0 2 2 2 1 Purine nucleobase transmembrane transport EamA PF00892.20 KKK13153.1 - 6.7e-05 23.1 5.8 6.7e-05 23.1 5.8 3.2 3 2 1 4 4 4 1 EamA-like transporter family UAA PF08449.11 KKK13153.1 - 0.00066 19.0 0.3 0.0012 18.1 0.3 1.4 1 0 0 1 1 1 1 UAA transporter family Multi_Drug_Res PF00893.19 KKK13153.1 - 1.1 10.0 13.4 2.9 8.6 2.1 3.1 2 2 0 2 2 2 0 Small Multidrug Resistance protein Neurensin PF14927.6 KKK13153.1 - 1.2 8.9 7.8 5.6 6.7 2.1 3.2 2 1 0 2 2 2 0 Neurensin vATP-synt_E PF01991.18 KKK13154.1 - 9.7e-63 211.2 12.2 1.1e-62 211.0 12.2 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit PhoLip_ATPase_C PF16212.5 KKK13156.1 - 2.6e-82 276.4 24.4 2.6e-82 276.4 24.4 2.6 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KKK13156.1 - 3.7e-19 68.2 0.6 1.1e-18 66.7 0.6 1.8 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 KKK13156.1 - 5.2e-14 53.0 0.0 4.5e-09 36.9 0.0 2.6 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KKK13156.1 - 3.6e-11 43.0 0.0 1.7e-10 40.8 0.0 2.0 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 KKK13156.1 - 0.0016 18.0 0.0 0.0016 18.0 0.0 2.7 3 1 0 3 3 3 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KKK13156.1 - 0.07 12.8 0.1 0.16 11.7 0.1 1.5 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Robl_LC7 PF03259.17 KKK13158.1 - 3.5e-05 23.5 0.2 0.016 14.9 0.0 2.9 3 0 0 3 3 3 2 Roadblock/LC7 domain SPX PF03105.19 KKK13158.1 - 3.3 7.5 7.1 4.3 7.2 7.1 1.1 1 0 0 1 1 1 0 SPX domain SOG2 PF10428.9 KKK13158.1 - 6.7 5.8 9.5 7.7 5.6 9.5 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein SEN1_N PF12726.7 KKK13159.1 - 1.1e-211 705.0 10.0 1.5e-211 704.6 10.0 1.1 1 0 0 1 1 1 1 SEN1 N terminal AAA_11 PF13086.6 KKK13159.1 - 4.3e-71 239.8 0.8 4.3e-71 239.8 0.8 2.8 3 0 0 3 3 3 1 AAA domain AAA_12 PF13087.6 KKK13159.1 - 1.7e-61 207.3 0.0 4.1e-61 206.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KKK13159.1 - 2.7e-09 37.0 0.1 2e-05 24.4 0.1 3.0 3 0 0 3 3 3 2 AAA domain AAA_19 PF13245.6 KKK13159.1 - 2.9e-07 30.9 0.0 8.2e-07 29.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain UvrD-helicase PF00580.21 KKK13159.1 - 1.2e-06 28.3 1.0 8.2e-06 25.5 0.1 2.6 2 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain Viral_helicase1 PF01443.18 KKK13159.1 - 4.7e-06 26.5 0.2 0.083 12.6 0.0 3.5 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase DEAD PF00270.29 KKK13159.1 - 0.00072 19.4 0.1 0.0023 17.7 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase zf-CCHC PF00098.23 KKK13159.1 - 0.0067 16.5 2.9 0.0067 16.5 2.9 3.1 3 0 0 3 3 2 2 Zinc knuckle AAA PF00004.29 KKK13159.1 - 0.078 13.4 0.1 0.41 11.1 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 KKK13159.1 - 0.083 11.9 0.0 0.16 11.0 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF1981 PF09324.10 KKK13159.1 - 0.092 12.6 0.0 0.32 10.9 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1981) ResIII PF04851.15 KKK13159.1 - 0.12 12.4 0.0 0.37 10.8 0.0 2.0 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit zf-CCHC_3 PF13917.6 KKK13159.1 - 0.19 11.7 19.5 1.4 8.9 1.7 4.1 1 1 1 2 2 2 0 Zinc knuckle Glyco_hydro_71 PF03659.14 KKK13160.1 - 2.7e-126 421.4 10.2 3.2e-126 421.2 10.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 DUF4434 PF14488.6 KKK13160.1 - 0.036 14.1 0.1 0.066 13.2 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4434) TUG-UBL1 PF11470.8 KKK13163.1 - 2e-24 85.6 0.1 1e-23 83.3 0.0 2.2 2 0 0 2 2 2 1 TUG ubiquitin-like domain UBX PF00789.20 KKK13163.1 - 0.00054 20.1 0.4 0.0026 17.9 0.0 2.2 2 0 0 2 2 2 1 UBX domain RBD PF02196.15 KKK13163.1 - 0.02 15.0 0.2 0.22 11.6 0.0 2.6 3 0 0 3 3 3 0 Raf-like Ras-binding domain Proteasome PF00227.26 KKK13164.1 - 2.3e-38 131.6 0.0 2.6e-38 131.4 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Ank_2 PF12796.7 KKK13165.1 - 1.2e-18 67.4 0.0 1.6e-17 63.9 0.0 2.9 3 1 0 3 3 3 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KKK13165.1 - 9e-14 50.3 0.0 0.00072 19.8 0.0 4.3 3 0 0 3 3 3 3 Ankyrin repeat Ank PF00023.30 KKK13165.1 - 4.4e-13 49.0 0.0 0.00083 19.7 0.0 4.0 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 KKK13165.1 - 2.7e-11 43.5 0.0 0.042 14.2 0.0 3.8 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 KKK13165.1 - 3.6e-09 37.0 0.0 7.8e-05 23.2 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeats (many copies) AAA_22 PF13401.6 KKK13165.1 - 0.00011 22.5 0.0 0.0082 16.4 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KKK13165.1 - 0.00011 22.6 0.1 0.0008 19.8 0.0 2.4 2 1 0 3 3 3 1 AAA ATPase domain NACHT PF05729.12 KKK13165.1 - 0.018 14.9 0.0 0.048 13.6 0.0 1.7 1 0 0 1 1 1 0 NACHT domain AAA_14 PF13173.6 KKK13165.1 - 0.061 13.4 0.0 0.18 11.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain Glyco_hydro_71 PF03659.14 KKK13166.1 - 5.8e-129 430.2 7.8 6.7e-129 430.0 7.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 Ufd2P_core PF10408.9 KKK13167.1 - 1.7e-221 737.2 9.9 2.1e-221 736.9 9.9 1.1 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.15 KKK13167.1 - 5.8e-27 93.7 3.6 5.9e-27 93.6 1.0 2.5 2 0 0 2 2 2 1 U-box domain Endonuc-MspI PF09208.10 KKK13167.1 - 0.066 12.6 0.1 0.12 11.8 0.1 1.3 1 0 0 1 1 1 0 Restriction endonuclease MspI Focal_AT PF03623.13 KKK13167.1 - 0.13 12.2 0.0 0.39 10.7 0.0 1.7 1 0 0 1 1 1 0 Focal adhesion targeting region Steroid_dh PF02544.16 KKK13168.1 - 2.6e-15 56.7 1.0 1.8e-10 41.0 1.1 3.4 3 1 0 3 3 3 2 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 KKK13168.1 - 0.00093 18.8 0.0 0.002 17.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Motilin_ghrelin PF04644.12 KKK13168.1 - 0.091 12.6 0.7 0.18 11.6 0.7 1.4 1 0 0 1 1 1 0 Motilin/ghrelin HATPase_c PF02518.26 KKK13169.1 - 1.9e-21 76.7 0.0 4.3e-21 75.5 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KKK13169.1 - 3.5e-16 59.4 0.2 0.00024 21.3 0.0 3.6 3 0 0 3 3 3 3 Response regulator receiver domain HisKA PF00512.25 KKK13169.1 - 7.4e-06 25.9 0.0 2.4e-05 24.3 0.0 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 KKK13169.1 - 0.061 13.1 0.0 0.15 11.8 0.0 1.6 2 0 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase EHN PF06441.12 KKK13170.1 - 6.8e-35 119.7 1.1 9.5e-34 116.0 0.2 2.4 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 KKK13170.1 - 4.7e-14 52.7 0.0 8.3e-14 51.9 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KKK13170.1 - 4.5e-06 27.4 0.4 4.5e-06 27.4 0.4 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Aim19 PF10315.9 KKK13171.1 - 1.4e-05 25.4 0.2 1.7e-05 25.1 0.2 1.3 1 0 0 1 1 1 1 Altered inheritance of mitochondria protein 19 DUF1977 PF09320.11 KKK13172.1 - 2.9e-32 111.0 0.0 5.3e-32 110.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) DnaJ PF00226.31 KKK13172.1 - 8e-22 77.1 0.1 1.6e-21 76.2 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain SANT_DAMP1_like PF16282.5 KKK13173.1 - 8e-31 106.1 2.6 1.4e-30 105.3 2.6 1.4 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 DMAP1 PF05499.12 KKK13173.1 - 8.7e-06 25.7 8.5 2.1e-05 24.5 3.1 2.9 2 1 1 3 3 3 1 DNA methyltransferase 1-associated protein 1 (DMAP1) Myb_DNA-binding PF00249.31 KKK13173.1 - 0.055 13.7 0.0 0.2 11.9 0.0 2.1 1 0 0 1 1 1 0 Myb-like DNA-binding domain DUF1180 PF06679.12 KKK13173.1 - 1.1 9.7 16.6 0.95 9.9 3.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) EMP24_GP25L PF01105.24 KKK13174.1 - 9.9e-50 169.0 0.1 1.2e-49 168.8 0.1 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF2721 PF11026.8 KKK13174.1 - 0.61 10.0 4.0 0.21 11.5 0.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) Meth_synt_2 PF01717.18 KKK13175.1 - 5.7e-153 508.9 0.0 1.3e-149 497.9 0.0 2.3 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 KKK13175.1 - 8.6e-119 396.7 0.0 4.3e-111 371.4 0.0 3.0 3 0 0 3 3 3 2 Cobalamin-independent synthase, N-terminal domain SHOCT PF09851.9 KKK13175.1 - 0.26 11.1 1.4 0.48 10.2 0.2 2.2 2 0 0 2 2 2 0 Short C-terminal domain PCI PF01399.27 KKK13182.1 - 2.8e-11 43.9 0.0 4.8e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 PCI domain eIF3m_C_helix PF18005.1 KKK13182.1 - 6.4e-10 38.5 3.9 6.4e-10 38.5 3.9 1.8 2 0 0 2 2 2 1 eIF3 subunit M, C-terminal helix ATG22 PF11700.8 KKK13182.1 - 0.12 10.9 0.3 0.72 8.4 0.0 1.9 1 1 0 2 2 2 0 Vacuole effluxer Atg22 like STAS_2 PF13466.6 KKK13182.1 - 3 8.3 9.1 2.6 8.5 0.1 3.3 3 1 0 3 3 3 0 STAS domain Arylsulfotran_2 PF14269.6 KKK13183.1 - 3.6e-48 164.5 0.2 5.2e-48 163.9 0.2 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) ADK PF00406.22 KKK13183.1 - 1.6e-34 119.2 0.0 9.1e-17 61.6 0.0 2.4 2 0 0 2 2 2 2 Adenylate kinase AAA_17 PF13207.6 KKK13183.1 - 5.4e-25 88.4 0.1 1.1e-12 48.5 0.0 2.5 1 1 1 2 2 2 2 AAA domain Arylsulfotrans PF05935.11 KKK13183.1 - 2.7e-12 46.3 0.4 1.1e-10 41.0 0.4 2.4 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) AAA_18 PF13238.6 KKK13183.1 - 0.0018 18.8 0.0 0.0053 17.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 KKK13183.1 - 0.071 12.8 1.2 1.9 8.1 0.0 2.6 3 0 0 3 3 3 0 Thymidylate kinase DUF2057 PF09829.9 KKK13183.1 - 0.091 12.9 0.4 0.19 11.9 0.4 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2057) Ribosomal_60s PF00428.19 KKK13183.1 - 4.5 7.9 27.8 0.25 12.0 12.1 2.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein Hexokinase_2 PF03727.16 KKK13184.1 - 3e-57 193.8 0.0 4.1e-57 193.4 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 KKK13184.1 - 1.6e-47 162.0 0.0 2.5e-47 161.3 0.0 1.3 1 0 0 1 1 1 1 Hexokinase RhoGAP PF00620.27 KKK13185.1 - 5.9e-48 162.5 0.0 2.5e-47 160.5 0.0 2.0 2 0 0 2 2 2 1 RhoGAP domain FCH PF00611.23 KKK13185.1 - 6.4e-12 45.6 2.4 1.9e-11 44.1 0.2 2.6 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain V-ATPase_G_2 PF16999.5 KKK13185.1 - 0.33 11.4 10.3 0.8 10.2 3.3 2.4 2 0 0 2 2 2 0 Vacuolar (H+)-ATPase G subunit DUF745 PF05335.13 KKK13185.1 - 0.6 9.8 7.1 0.94 9.2 1.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF745) OmpH PF03938.14 KKK13185.1 - 4.3 7.7 10.4 15 5.9 8.1 2.6 2 1 1 3 3 3 0 Outer membrane protein (OmpH-like) Alanine_zipper PF11839.8 KKK13185.1 - 6.4 7.2 9.9 0.73 10.2 1.7 2.6 3 0 0 3 3 3 0 Alanine-zipper, major outer membrane lipoprotein MBA1 PF07961.11 KKK13186.1 - 0.013 14.5 0.0 0.022 13.8 0.0 1.4 1 1 0 1 1 1 0 MBA1-like protein Fungal_trans PF04082.18 KKK13187.1 - 8.7e-18 64.3 0.0 1.6e-17 63.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK13187.1 - 3.9e-06 26.9 9.5 6.8e-06 26.1 9.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain V-SNARE PF05008.15 KKK13187.1 - 0.13 12.7 0.2 0.33 11.4 0.2 1.7 2 0 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus adh_short_C2 PF13561.6 KKK13188.1 - 2.4e-49 168.0 0.8 3.6e-49 167.4 0.8 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KKK13188.1 - 2.1e-40 138.3 0.4 3.4e-40 137.6 0.4 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Fungal_trans PF04082.18 KKK13188.1 - 1.3e-21 76.8 1.4 2.2e-21 76.1 1.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain KR PF08659.10 KKK13188.1 - 1.1e-08 35.2 0.3 3e-08 33.8 0.0 1.8 2 0 0 2 2 2 1 KR domain EOS1 PF12326.8 KKK13189.1 - 3.7e-12 46.5 9.2 3.7e-12 46.5 9.2 2.0 1 1 1 2 2 2 1 N-glycosylation protein UPF0139 PF03669.13 KKK13190.1 - 3.7e-05 23.5 0.3 5.2e-05 23.0 0.3 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0139) SUI1 PF01253.22 KKK13191.1 - 2.5e-28 98.4 3.9 3.3e-28 98.0 3.9 1.2 1 0 0 1 1 1 1 Translation initiation factor SUI1 GlcNAc-1_reg PF18440.1 KKK13191.1 - 0.048 13.9 0.4 0.077 13.2 0.4 1.3 1 0 0 1 1 1 0 Putative GlcNAc-1 phosphotransferase regulatory domain RRM_1 PF00076.22 KKK13192.1 - 0.0003 20.6 0.0 0.00054 19.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Med12 PF09497.10 KKK13193.1 - 4.2e-28 97.4 0.8 1.1e-27 96.0 0.8 1.8 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 FH2 PF02181.23 KKK13194.1 - 3.3e-92 309.5 3.3 3.8e-92 309.3 3.3 1.0 1 0 0 1 1 1 1 Formin Homology 2 Domain Nrap_D6 PF17407.2 KKK13194.1 - 0.041 14.1 0.4 0.65 10.2 0.1 2.4 2 0 0 2 2 2 0 Nrap protein domain 6 DHBP_synthase PF00926.19 KKK13198.1 - 6.2e-79 264.0 0.0 7.4e-79 263.7 0.0 1.1 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase APS_kinase PF01583.20 KKK13201.1 - 1.3e-70 236.3 0.0 1.6e-70 236.0 0.0 1.1 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.6 KKK13201.1 - 3.5e-06 27.2 0.0 7.8e-06 26.1 0.0 1.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KKK13201.1 - 0.00011 22.8 0.0 0.00016 22.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KKK13201.1 - 0.00061 20.2 0.0 0.00083 19.8 0.0 1.2 1 1 0 1 1 1 1 AAA ATPase domain KTI12 PF08433.10 KKK13201.1 - 0.0048 16.4 0.0 0.0078 15.7 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 G-alpha PF00503.20 KKK13201.1 - 0.037 13.2 0.0 0.063 12.4 0.0 1.5 2 0 0 2 2 2 0 G-protein alpha subunit Zeta_toxin PF06414.12 KKK13201.1 - 0.047 13.0 0.0 0.068 12.4 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_29 PF13555.6 KKK13201.1 - 0.11 12.3 0.1 0.18 11.5 0.1 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain Pyr_redox_3 PF13738.6 KKK13242.1 - 2.3e-20 73.1 0.0 3.2e-17 62.7 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KKK13242.1 - 3.9e-16 58.6 0.1 4e-13 48.6 0.0 2.4 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KKK13242.1 - 7.5e-15 54.9 0.0 3.1e-12 46.4 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KKK13242.1 - 1.3e-10 41.0 0.0 3.8e-07 29.6 0.0 3.0 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KKK13242.1 - 3.2e-06 27.3 0.0 2.4e-05 24.4 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KKK13242.1 - 7.3e-05 23.2 0.0 0.94 10.1 0.0 2.9 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KKK13242.1 - 0.002 17.3 0.0 0.0057 15.8 0.0 1.7 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 KKK13242.1 - 0.0027 16.9 0.1 0.0049 16.0 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.19 KKK13242.1 - 0.0027 17.0 0.0 0.017 14.4 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 KKK13242.1 - 0.0027 17.3 0.5 0.21 11.2 0.0 3.0 2 1 1 3 3 3 1 FAD dependent oxidoreductase GIDA PF01134.22 KKK13242.1 - 0.0061 15.7 0.3 0.28 10.2 0.0 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A HI0933_like PF03486.14 KKK13242.1 - 0.014 14.1 0.8 0.046 12.4 0.0 2.2 3 0 0 3 3 3 0 HI0933-like protein Thi4 PF01946.17 KKK13242.1 - 0.022 14.0 0.0 0.21 10.8 0.0 2.3 2 0 0 2 2 2 0 Thi4 family NAD_binding_9 PF13454.6 KKK13242.1 - 0.03 14.3 0.1 8.4 6.4 0.0 2.9 3 0 0 3 3 3 0 FAD-NAD(P)-binding 2-Hacid_dh_C PF02826.19 KKK13242.1 - 0.03 13.7 0.0 0.073 12.4 0.0 1.6 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 KKK13242.1 - 0.039 13.9 0.1 3.9 7.3 0.0 2.3 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.18 KKK13242.1 - 0.071 13.4 0.0 0.16 12.2 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain MutS_V PF00488.21 KKK13254.1 - 7.3e-68 228.3 0.1 1.3e-67 227.5 0.1 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KKK13254.1 - 9.6e-42 143.4 0.0 2.5e-41 142.0 0.0 1.8 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 KKK13254.1 - 7.5e-33 113.1 0.0 2.3e-32 111.6 0.0 1.9 2 0 0 2 2 2 1 MutS domain I MutS_II PF05188.17 KKK13254.1 - 2e-14 54.0 0.0 8.2e-14 52.0 0.0 2.1 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.18 KKK13254.1 - 3.1e-12 46.7 0.2 7e-12 45.5 0.2 1.6 1 0 0 1 1 1 1 MutS family domain IV AAA_23 PF13476.6 KKK13254.1 - 0.066 13.7 0.5 0.43 11.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 KKK13254.1 - 0.096 12.4 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_27 PF13514.6 KKK13254.1 - 0.14 11.7 0.0 0.33 10.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain tRNA-synt_2 PF00152.20 KKK13255.1 - 9.1e-91 304.2 0.0 1.2e-90 303.8 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KKK13255.1 - 0.00084 19.3 0.0 0.0018 18.2 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_1b PF00579.25 KKK13256.1 - 4.1e-74 249.5 0.0 6e-74 249.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) TyrRSs_C PF16714.5 KKK13256.1 - 2.7e-50 169.2 0.0 4.5e-50 168.5 0.0 1.4 1 0 0 1 1 1 1 Tyrosyl-tRNA synthetase C-terminal domain PhaP_Bmeg PF09602.10 KKK13256.1 - 0.072 13.0 0.5 0.17 11.8 0.3 1.8 2 0 0 2 2 2 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) DUF2852 PF11014.8 KKK13256.1 - 0.26 11.5 1.8 2.1 8.5 0.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2852) Med8 PF10232.9 KKK13257.1 - 1.9e-56 191.3 2.0 2.3e-56 191.0 2.0 1.0 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 PPP4R2 PF09184.11 KKK13257.1 - 0.065 12.8 3.6 0.091 12.3 3.6 1.2 1 0 0 1 1 1 0 PPP4R2 TFIIA PF03153.13 KKK13257.1 - 0.075 13.0 4.8 0.1 12.6 4.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CENP-B_dimeris PF09026.10 KKK13257.1 - 0.096 13.1 11.1 0.21 12.0 11.1 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Nop53 PF07767.11 KKK13257.1 - 0.4 10.0 9.0 0.63 9.4 9.0 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Nucleo_P87 PF07267.11 KKK13257.1 - 0.76 8.6 3.2 0.95 8.2 3.2 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 NOA36 PF06524.12 KKK13257.1 - 0.95 8.7 7.8 1.7 7.9 7.8 1.4 1 0 0 1 1 1 0 NOA36 protein Myc_N PF01056.18 KKK13257.1 - 3.8 7.3 12.9 15 5.4 12.8 1.8 1 1 0 1 1 1 0 Myc amino-terminal region Lsr2 PF11774.8 KKK13257.1 - 5.8 7.1 6.8 3.4 7.8 4.1 2.1 2 0 0 2 2 2 0 Lsr2 DNA_pol_phi PF04931.13 KKK13257.1 - 7.9 4.4 13.0 0.47 8.5 6.9 1.8 2 0 0 2 2 2 0 DNA polymerase phi UbiA PF01040.18 KKK13258.1 - 5.2e-58 196.3 17.7 5.2e-58 196.3 17.7 1.6 1 1 1 2 2 2 1 UbiA prenyltransferase family PQ-loop PF04193.14 KKK13259.1 - 1.1e-19 70.0 4.5 8.4e-10 38.3 1.2 2.7 2 0 0 2 2 2 2 PQ loop repeat Fungal_trans_2 PF11951.8 KKK13260.1 - 5.4e-08 32.1 0.4 5.4e-08 32.1 0.4 2.1 2 1 1 3 3 3 1 Fungal specific transcription factor domain HECT PF00632.25 KKK13260.1 - 0.17 11.4 0.0 0.39 10.2 0.0 1.6 1 0 0 1 1 1 0 HECT-domain (ubiquitin-transferase) DUF3602 PF12223.8 KKK13261.1 - 0.0005 20.6 0.4 0.0005 20.6 0.4 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3602) DUF1479 PF07350.12 KKK13262.1 - 1.1e-170 567.9 0.0 1.3e-170 567.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) CRAL_TRIO PF00650.20 KKK13263.1 - 2.1e-25 89.3 0.0 5.1e-25 88.0 0.0 1.6 2 0 0 2 2 2 1 CRAL/TRIO domain SPATA48 PF15073.6 KKK13263.1 - 0.027 14.7 0.2 0.068 13.5 0.2 1.6 1 0 0 1 1 1 0 Spermatogenesis-associated protein 48 DUF5476 PF17570.2 KKK13263.1 - 0.75 10.2 4.3 1.7 9.1 4.3 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5476) EMC1_C PF07774.13 KKK13264.1 - 3.6e-74 249.1 0.0 1.2e-73 247.4 0.0 1.8 2 0 0 2 2 2 1 ER membrane protein complex subunit 1, C-terminal PQQ_2 PF13360.6 KKK13264.1 - 1.7e-24 86.7 12.5 3.3e-22 79.2 2.1 3.3 2 1 1 3 3 3 2 PQQ-like domain PQQ PF01011.21 KKK13264.1 - 9.5e-09 34.8 5.2 0.1 12.6 0.2 5.8 6 0 0 6 6 6 2 PQQ enzyme repeat PQQ_3 PF13570.6 KKK13264.1 - 0.00068 20.1 1.3 0.1 13.1 0.0 4.5 3 1 1 4 4 4 1 PQQ-like domain Aa_trans PF01490.18 KKK13265.1 - 1.8e-95 320.1 14.7 2.9e-95 319.4 14.7 1.3 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein adh_short PF00106.25 KKK13265.1 - 7.2e-36 123.5 0.0 1.2e-35 122.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KKK13265.1 - 1.2e-29 103.5 0.0 2.3e-29 102.6 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Trp_Tyr_perm PF03222.13 KKK13265.1 - 0.00011 21.4 17.2 0.00011 21.4 17.2 1.5 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family KR PF08659.10 KKK13265.1 - 0.0009 19.2 0.0 0.01 15.7 0.0 2.2 2 0 0 2 2 2 1 KR domain DUF1776 PF08643.10 KKK13265.1 - 0.13 11.6 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Rad51 PF08423.11 KKK13267.1 - 1.1e-112 375.4 0.0 1.4e-112 375.1 0.0 1.1 1 0 0 1 1 1 1 Rad51 RecA PF00154.21 KKK13267.1 - 6.1e-12 45.6 0.0 8.2e-12 45.1 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein HHH_5 PF14520.6 KKK13267.1 - 1.1e-08 35.6 1.8 2.4e-08 34.5 0.7 2.1 2 0 0 2 2 2 1 Helix-hairpin-helix domain ATPase PF06745.13 KKK13267.1 - 4.7e-07 29.4 0.0 1.1e-06 28.2 0.0 1.7 1 1 0 1 1 1 1 KaiC AAA_25 PF13481.6 KKK13267.1 - 0.00011 21.8 0.0 0.00016 21.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 KKK13267.1 - 0.086 12.2 0.0 0.86 8.9 0.0 2.1 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain PAXNEB PF05625.11 KKK13267.1 - 0.2 10.8 0.0 1.2 8.2 0.0 1.9 2 0 0 2 2 2 0 PAXNEB protein UDPGP PF01704.18 KKK13268.1 - 2.8e-56 191.0 0.0 3.6e-56 190.6 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.7 KKK13268.1 - 0.0068 16.8 0.0 0.018 15.4 0.0 1.7 2 0 0 2 2 2 1 MobA-like NTP transferase domain DegV PF02645.16 KKK13268.1 - 0.19 11.0 0.2 0.31 10.4 0.2 1.2 1 0 0 1 1 1 0 Uncharacterised protein, DegV family COG1307 zf-CCHC PF00098.23 KKK13269.1 - 9.6e-46 151.9 57.6 2.2e-07 30.7 0.9 7.1 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.6 KKK13269.1 - 1e-09 38.0 38.6 0.038 13.7 0.4 7.1 7 0 0 7 7 7 6 Zinc knuckle zf-CCHC_3 PF13917.6 KKK13269.1 - 4.5e-08 32.9 41.3 0.0044 17.0 0.2 7.0 4 2 2 6 6 6 4 Zinc knuckle zf-CCHC_5 PF14787.6 KKK13269.1 - 0.00022 20.8 41.4 0.019 14.6 0.9 7.0 4 2 3 7 7 7 5 GAG-polyprotein viral zinc-finger Pro_isomerase PF00160.21 KKK13271.1 - 6.3e-33 114.3 0.0 1e-32 113.6 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.22 KKK13271.1 - 6.2e-16 58.0 0.0 1.4e-15 56.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Methyltransf_16 PF10294.9 KKK13272.1 - 2.2e-05 24.3 0.0 0.00035 20.4 0.1 2.1 2 0 0 2 2 2 1 Lysine methyltransferase Ribosomal_S24e PF01282.19 KKK13273.1 - 8.1e-36 121.8 0.1 1.6e-35 120.9 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S24e RRXRR PF14239.6 KKK13273.1 - 2.4 8.0 10.8 0.03 14.2 2.1 2.0 1 1 0 2 2 2 0 RRXRR protein DivIVA PF05103.13 KKK13274.1 - 0.003 17.6 23.2 0.0034 17.5 9.7 3.5 2 1 2 4 4 4 2 DivIVA protein Fib_alpha PF08702.10 KKK13274.1 - 0.61 10.3 10.7 1.7 8.8 1.0 3.0 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Phage_GP20 PF06810.11 KKK13274.1 - 1.2 9.0 9.8 0.53 10.1 1.7 3.0 2 1 1 3 3 3 0 Phage minor structural protein GP20 CLTH PF10607.9 KKK13275.1 - 3.3e-33 114.6 0.0 5.1e-33 114.0 0.0 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain SPRY PF00622.28 KKK13275.1 - 3.2e-19 69.2 0.3 6.2e-19 68.3 0.3 1.5 1 0 0 1 1 1 1 SPRY domain LisH PF08513.11 KKK13275.1 - 0.00021 21.2 0.6 0.00052 19.9 0.1 2.0 2 0 0 2 2 2 1 LisH OpuAC PF04069.12 KKK13275.1 - 0.03 13.9 0.7 1.8 8.1 0.4 2.3 1 1 1 2 2 2 0 Substrate binding domain of ABC-type glycine betaine transport system MFS_1 PF07690.16 KKK13292.1 - 9.7e-31 107.0 56.1 5.7e-29 101.1 19.1 2.7 2 1 1 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.13 KKK13292.1 - 9.4e-17 60.6 14.4 2.1e-16 59.5 14.4 1.6 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF4668 PF15701.5 KKK13292.1 - 0.027 14.3 4.1 0.29 11.0 0.1 3.3 3 1 1 4 4 4 0 Domain of unknown function (DUF4668) LAGLIDADG_2 PF03161.13 KKK13292.1 - 0.045 13.8 0.0 0.13 12.3 0.0 1.8 1 0 0 1 1 1 0 LAGLIDADG DNA endonuclease family Pec_lyase_C PF00544.19 KKK13293.1 - 8.5e-11 41.8 7.3 2.1e-09 37.3 7.3 2.4 1 1 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 KKK13293.1 - 1.3e-05 25.1 21.1 0.00044 20.1 5.9 2.3 1 1 1 2 2 2 2 Right handed beta helix region GST_N PF02798.20 KKK13294.1 - 3.4e-12 46.5 0.0 5.8e-12 45.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KKK13294.1 - 5.1e-11 42.7 0.0 8e-11 42.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KKK13294.1 - 1.8e-08 34.3 0.6 2.4e-08 33.9 0.1 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KKK13294.1 - 2.6e-07 30.7 0.0 6e-07 29.6 0.0 1.5 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KKK13294.1 - 2.8e-07 30.8 0.0 5.4e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KKK13294.1 - 8.1e-05 22.8 0.0 0.00014 22.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.4 KKK13294.1 - 0.0029 18.3 0.0 0.006 17.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain PapG_N PF03627.13 KKK13295.1 - 0.13 11.9 0.0 0.16 11.6 0.0 1.1 1 0 0 1 1 1 0 PapG carbohydrate binding domain FAD_binding_4 PF01565.23 KKK13296.1 - 5.3e-33 113.7 7.1 2.9e-32 111.3 7.6 2.0 3 0 0 3 3 3 1 FAD binding domain BBE PF08031.12 KKK13296.1 - 1.3e-06 28.3 0.1 2.7e-06 27.4 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like FAD_binding_4 PF01565.23 KKK13297.1 - 3.9e-32 110.9 7.2 6.7e-32 110.1 7.2 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KKK13297.1 - 3.6e-09 36.6 0.0 7.3e-09 35.6 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like IBR PF01485.21 KKK13298.1 - 3e-05 24.2 4.7 3e-05 24.2 4.7 5.2 5 0 0 5 5 5 1 IBR domain, a half RING-finger domain VWA_2 PF13519.6 KKK13298.1 - 0.006 17.2 0.0 0.015 15.9 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain WLM PF08325.10 KKK13300.1 - 6.7e-39 133.9 0.3 7.8e-39 133.7 0.3 1.0 1 0 0 1 1 1 1 WLM domain DUF45 PF01863.17 KKK13300.1 - 1.4e-05 25.2 0.5 2e-05 24.7 0.5 1.2 1 0 0 1 1 1 1 Protein of unknown function DUF45 SprT-like PF10263.9 KKK13300.1 - 0.0013 18.6 0.3 0.0021 17.9 0.3 1.3 1 1 0 1 1 1 1 SprT-like family DUF3920 PF13058.6 KKK13300.1 - 0.063 13.5 0.0 0.096 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3920) Mito_carr PF00153.27 KKK13301.1 - 5.7e-41 138.4 0.1 1.2e-24 86.0 0.0 2.9 2 1 1 3 3 3 2 Mitochondrial carrier protein EF-hand_7 PF13499.6 KKK13301.1 - 8.7e-20 70.9 5.0 4.2e-09 36.7 0.9 3.4 3 1 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 KKK13301.1 - 1.5e-19 68.2 1.3 1.6e-06 27.6 0.1 5.5 5 0 0 5 5 5 4 EF-hand domain EF-hand_1 PF00036.32 KKK13301.1 - 1.2e-17 62.1 3.2 9.4e-07 28.0 0.1 5.4 6 0 0 6 6 6 3 EF hand EF-hand_8 PF13833.6 KKK13301.1 - 3.6e-11 42.7 5.1 0.0058 16.5 0.0 5.6 5 1 1 6 6 6 5 EF-hand domain pair EF-hand_5 PF13202.6 KKK13301.1 - 5.3e-10 38.3 0.9 3.1e-05 23.3 0.1 4.5 4 0 0 4 4 4 1 EF hand EF-hand_9 PF14658.6 KKK13301.1 - 0.0012 19.1 0.0 6.1 7.2 0.0 3.5 3 0 0 3 3 3 2 EF-hand domain Gaa1 PF04114.14 KKK13301.1 - 0.14 11.2 0.0 0.2 10.6 0.0 1.1 1 0 0 1 1 1 0 Gaa1-like, GPI transamidase component Prenylcys_lyase PF07156.14 KKK13302.1 - 6.1e-98 328.3 0.0 7.7e-98 327.9 0.0 1.1 1 0 0 1 1 1 1 Prenylcysteine lyase NAD_binding_8 PF13450.6 KKK13302.1 - 1e-12 48.1 0.0 2.6e-12 46.8 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 KKK13302.1 - 1.2e-11 44.7 0.0 2.5e-11 43.5 0.0 1.5 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.24 KKK13302.1 - 1.2e-08 35.0 0.2 7.3e-06 25.8 0.7 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KKK13302.1 - 1.6e-05 24.9 0.2 0.00043 20.3 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 KKK13302.1 - 0.00054 19.3 0.1 0.023 14.0 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KKK13302.1 - 0.0061 15.3 0.3 0.97 8.1 0.3 2.1 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox PF00070.27 KKK13302.1 - 0.0086 16.6 0.1 5.2 7.7 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KKK13302.1 - 0.047 12.8 0.0 5.7 6.0 0.0 2.1 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 KKK13302.1 - 0.061 12.6 0.1 0.11 11.7 0.1 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.6 KKK13302.1 - 0.1 11.8 0.1 3.7 6.7 0.1 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KKK13302.1 - 0.12 11.4 0.7 0.73 8.8 0.4 1.9 2 0 0 2 2 2 0 FAD binding domain PDCD2_C PF04194.13 KKK13303.1 - 5.4e-40 137.3 0.0 1.8e-39 135.6 0.0 1.9 3 0 0 3 3 3 1 Programmed cell death protein 2, C-terminal putative domain Herpes_U47 PF05467.11 KKK13303.1 - 0.75 7.9 5.3 1.1 7.4 5.3 1.1 1 0 0 1 1 1 0 Herpesvirus glycoprotein U47 SHMT PF00464.19 KKK13304.1 - 4.1e-207 687.5 0.0 4.8e-207 687.3 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.21 KKK13304.1 - 1.2e-05 24.7 0.0 3.4e-05 23.2 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KKK13304.1 - 0.062 11.8 0.0 0.1 11.1 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 KKK13304.1 - 0.12 11.6 0.0 0.2 10.9 0.0 1.6 1 1 0 1 1 1 0 Beta-eliminating lyase DUF3040 PF11239.8 KKK13304.1 - 0.15 12.3 0.1 0.3 11.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) AcetylCoA_hydro PF02550.15 KKK13305.1 - 1.4e-52 178.5 0.0 2.1e-52 178.0 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain AcetylCoA_hyd_C PF13336.6 KKK13305.1 - 1e-26 93.7 0.0 2.2e-26 92.6 0.0 1.5 2 0 0 2 2 2 1 Acetyl-CoA hydrolase/transferase C-terminal domain DUF2076 PF09849.9 KKK13311.1 - 6.3e-05 23.2 2.9 6.3e-05 23.2 2.9 3.1 2 1 1 3 3 3 1 Uncharacterized protein conserved in bacteria (DUF2076) ATP-synt_E PF05680.12 KKK13311.1 - 5.7 7.4 7.0 0.91 9.9 0.3 2.2 2 0 0 2 2 2 0 ATP synthase E chain Na_Ca_ex PF01699.24 KKK13312.1 - 2e-39 135.0 38.8 1.3e-19 70.6 13.4 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Pep1_7 PF17232.2 KKK13312.1 - 0.92 10.0 4.4 2.2 8.8 3.1 2.4 2 0 0 2 2 2 0 Elicitor peptide 1-7 DUF5589 PF17672.1 KKK13312.1 - 0.94 9.4 2.9 1.1 9.2 0.1 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5589) UbiD PF01977.16 KKK13313.1 - 5.1e-97 325.3 0.1 5.9e-97 325.1 0.1 1.0 1 0 0 1 1 1 1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase DUF3756 PF12581.8 KKK13313.1 - 0.091 12.7 0.1 17 5.4 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3756) UbiD PF01977.16 KKK13314.1 - 1e-12 47.7 0.0 1.1e-12 47.5 0.0 1.0 1 0 0 1 1 1 1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase Anoctamin PF04547.12 KKK13315.1 - 5.7e-97 325.4 6.1 6.9e-97 325.1 6.1 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Flavoprotein PF02441.19 KKK13316.1 - 4e-25 88.4 0.1 4.8e-25 88.1 0.1 1.1 1 0 0 1 1 1 1 Flavoprotein NAD_binding_1 PF00175.21 KKK13317.1 - 7.3e-13 49.1 0.0 1.8e-12 47.8 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Globin PF00042.22 KKK13317.1 - 2.1e-08 34.7 0.1 7.1e-08 33.0 0.0 2.0 3 0 0 3 3 3 1 Globin FAD_binding_6 PF00970.24 KKK13317.1 - 5.9e-06 26.6 0.0 9.5e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Protoglobin PF11563.8 KKK13317.1 - 0.002 18.0 0.0 0.0061 16.5 0.0 1.7 1 1 0 1 1 1 1 Protoglobin NAD_binding_6 PF08030.12 KKK13317.1 - 0.054 13.6 0.0 0.36 10.9 0.0 2.2 2 1 1 3 3 3 0 Ferric reductase NAD binding domain MIP PF00230.20 KKK13318.1 - 2.6e-44 151.6 8.7 3.3e-44 151.3 8.7 1.1 1 0 0 1 1 1 1 Major intrinsic protein Bact_transglu_N PF08379.10 KKK13318.1 - 0.43 11.5 1.4 1 10.3 0.3 2.0 2 0 0 2 2 2 0 Bacterial transglutaminase-like N-terminal region AA_permease_2 PF13520.6 KKK13319.1 - 1.8e-69 234.6 49.1 2.5e-69 234.2 49.1 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KKK13319.1 - 6.5e-10 38.2 43.8 1.6e-09 36.9 43.9 1.6 1 1 0 1 1 1 1 Amino acid permease RIFIN PF02009.16 KKK13320.1 - 0.35 10.7 1.5 0.39 10.5 1.5 1.2 1 0 0 1 1 1 0 Rifin MID_MedPIWI PF18296.1 KKK13320.1 - 0.89 9.3 4.7 1.1 8.9 4.7 1.2 1 0 0 1 1 1 0 MID domain of medPIWI Macoilin PF09726.9 KKK13320.1 - 2.9 6.3 8.3 3.3 6.1 8.3 1.1 1 0 0 1 1 1 0 Macoilin family Tmemb_cc2 PF10267.9 KKK13320.1 - 4 6.5 5.5 4.9 6.2 5.5 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein zf-rbx1 PF12678.7 KKK13347.1 - 5.4e-09 36.2 5.0 1.8e-08 34.6 5.0 2.0 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 KKK13347.1 - 1e-07 32.2 9.1 5.5e-07 29.8 9.1 2.1 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KKK13347.1 - 9.5e-07 28.6 3.2 1.9e-06 27.6 3.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KKK13347.1 - 3.2e-06 27.1 2.7 6.7e-06 26.0 2.7 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KKK13347.1 - 2.8e-05 23.9 5.6 0.00016 21.5 2.2 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 KKK13347.1 - 4.1e-05 23.1 0.6 9.3e-05 22.0 0.6 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3HC4_2 PF13923.6 KKK13347.1 - 7.5e-05 22.5 3.5 7.5e-05 22.5 3.5 2.0 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KKK13347.1 - 9.5e-05 22.3 3.1 0.00037 20.4 3.4 1.8 1 1 1 2 2 2 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 KKK13347.1 - 0.0094 16.0 4.3 0.046 13.8 4.3 2.0 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 KKK13347.1 - 0.02 14.7 5.4 0.052 13.4 5.4 1.7 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KKK13347.1 - 0.028 14.6 1.1 0.069 13.3 1.1 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING-like PF08746.11 KKK13347.1 - 0.22 11.9 1.9 0.45 10.9 1.9 1.5 1 0 0 1 1 1 0 RING-like domain CopD PF05425.13 KKK13347.1 - 0.65 10.4 6.1 1.4 9.3 6.1 1.7 1 0 0 1 1 1 0 Copper resistance protein D zf-RING_11 PF17123.5 KKK13347.1 - 2.2 8.1 8.1 0.37 10.6 0.2 2.7 3 0 0 3 3 3 0 RING-like zinc finger zf-RING_4 PF14570.6 KKK13347.1 - 3.1 7.7 4.7 1.4 8.7 1.8 1.8 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain DUF3431 PF11913.8 KKK13348.1 - 9.3e-92 306.7 0.0 1.2e-91 306.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) MFS_1 PF07690.16 KKK13349.1 - 2.9e-21 75.8 19.0 2.9e-21 75.8 19.0 2.5 2 1 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KKK13349.1 - 4.4e-07 28.8 19.0 4.7e-07 28.7 7.2 2.7 3 0 0 3 3 3 2 MFS/sugar transport protein MFS_1_like PF12832.7 KKK13349.1 - 0.0019 17.1 9.7 0.0093 14.9 0.1 3.0 4 0 0 4 4 4 2 MFS_1 like family ATG22 PF11700.8 KKK13349.1 - 0.0021 16.8 0.4 0.012 14.3 0.1 2.2 2 1 0 2 2 2 1 Vacuole effluxer Atg22 like Kelch_4 PF13418.6 KKK13350.1 - 1.3e-33 114.7 10.0 1.1e-08 35.0 0.9 6.8 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_3 PF13415.6 KKK13350.1 - 1.4e-31 108.2 9.5 3.1e-06 27.3 0.2 5.9 5 0 0 5 5 5 5 Galactose oxidase, central domain Kelch_1 PF01344.25 KKK13350.1 - 8.9e-28 95.6 0.6 1.3e-11 43.9 0.1 6.1 6 0 0 6 6 6 4 Kelch motif Kelch_5 PF13854.6 KKK13350.1 - 1.1e-27 95.4 5.7 2.9e-07 30.3 0.1 6.4 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.6 KKK13350.1 - 2.5e-27 94.2 7.7 5.6e-11 42.3 0.5 6.4 4 1 2 6 6 6 5 Kelch motif Kelch_2 PF07646.15 KKK13350.1 - 7.8e-21 73.2 6.9 2e-08 33.9 0.4 6.5 6 0 0 6 6 6 4 Kelch motif Spc7 PF08317.11 KKK13350.1 - 0.00039 19.4 18.6 0.00039 19.4 18.6 5.2 3 2 2 5 5 5 1 Spc7 kinetochore protein TPR_MLP1_2 PF07926.12 KKK13350.1 - 0.0041 17.2 10.3 0.0041 17.2 10.3 8.8 5 2 1 8 8 8 2 TPR/MLP1/MLP2-like protein RAG2 PF03089.14 KKK13350.1 - 0.15 11.0 0.0 1.5 7.8 0.0 2.6 3 1 1 4 4 4 0 Recombination activating protein 2 DUF5398 PF17376.2 KKK13350.1 - 0.27 11.9 4.7 0.19 12.4 1.3 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5398) Raptor_N PF14538.6 KKK13352.1 - 1.4e-65 219.7 0.0 2.6e-65 218.8 0.0 1.5 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain WD40 PF00400.32 KKK13352.1 - 6.7e-07 29.9 3.4 0.52 11.3 0.0 5.8 4 1 0 4 4 4 2 WD domain, G-beta repeat BBS2_Mid PF14783.6 KKK13352.1 - 0.003 17.6 0.1 3 7.9 0.0 2.9 1 1 1 2 2 2 2 Ciliary BBSome complex subunit 2, middle region Atx10homo_assoc PF09759.9 KKK13352.1 - 0.038 14.0 0.0 0.096 12.7 0.0 1.7 1 0 0 1 1 1 0 Spinocerebellar ataxia type 10 protein domain EI24 PF07264.11 KKK13353.1 - 0.0098 16.2 0.9 0.014 15.6 0.9 1.2 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) DUF3439 PF11921.8 KKK13353.1 - 0.037 14.0 3.0 1.6 8.7 0.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) zf-RING_2 PF13639.6 KKK13354.1 - 4.8e-13 49.2 5.4 7.5e-13 48.6 5.4 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KKK13354.1 - 2.2e-09 36.9 2.2 2.2e-09 36.9 2.2 1.8 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KKK13354.1 - 5.2e-09 35.8 4.4 8.3e-09 35.2 4.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PA PF02225.22 KKK13354.1 - 6.5e-09 35.7 0.0 1.4e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 PA domain zf-rbx1 PF12678.7 KKK13354.1 - 8.3e-09 35.6 2.4 1.6e-08 34.7 2.4 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KKK13354.1 - 1.4e-08 34.5 3.6 2.2e-08 33.8 3.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KKK13354.1 - 1.9e-07 30.9 2.9 3e-07 30.3 2.9 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KKK13354.1 - 4.7e-06 26.4 3.1 7.1e-06 25.8 3.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KKK13354.1 - 6.4e-06 26.1 1.9 1.2e-05 25.2 0.4 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 KKK13354.1 - 0.00056 19.9 0.7 0.0011 19.0 0.7 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 KKK13354.1 - 0.0019 18.0 2.7 0.0033 17.2 2.7 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KKK13354.1 - 0.045 13.9 2.8 0.11 12.7 2.8 1.7 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.8 KKK13354.1 - 0.045 13.9 2.4 0.12 12.6 2.4 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 KKK13354.1 - 0.046 13.3 2.7 0.082 12.5 2.7 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type RINGv PF12906.7 KKK13354.1 - 0.35 11.0 4.1 0.67 10.1 4.1 1.5 1 0 0 1 1 1 0 RING-variant domain PHD PF00628.29 KKK13354.1 - 0.46 10.4 2.8 0.83 9.6 2.8 1.5 1 0 0 1 1 1 0 PHD-finger zf-RING_4 PF14570.6 KKK13354.1 - 0.63 9.9 3.1 1.1 9.1 3.1 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING-like PF08746.11 KKK13354.1 - 1.6 9.1 3.6 3 8.2 3.6 1.5 1 0 0 1 1 1 0 RING-like domain Histone PF00125.24 KKK13354.1 - 3.4 8.0 13.8 0.24 11.8 2.9 2.6 2 0 0 2 2 2 0 Core histone H2A/H2B/H3/H4 Arrestin_C PF02752.22 KKK13355.1 - 3.8e-20 72.7 0.0 2.1e-19 70.3 0.0 2.1 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 KKK13355.1 - 0.00012 22.2 0.1 0.14 12.2 0.0 2.4 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain EF-hand_9 PF14658.6 KKK13356.1 - 0.00067 19.9 0.0 0.4 11.0 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 KKK13356.1 - 0.12 12.9 0.0 2.4 8.7 0.0 2.7 2 2 0 2 2 2 0 EF-hand domain pair UCH PF00443.29 KKK13357.1 - 3.8e-33 115.1 0.4 6.7e-22 78.2 0.0 2.4 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KKK13357.1 - 5.4e-07 29.5 0.1 7.1e-06 25.8 0.1 2.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase PUL PF08324.11 KKK13358.1 - 7e-59 199.3 0.1 9.6e-59 198.9 0.1 1.2 1 0 0 1 1 1 1 PUL domain Peptidase_C97 PF05903.14 KKK13358.1 - 3.5e-41 140.5 0.0 5.8e-41 139.8 0.0 1.4 1 0 0 1 1 1 1 PPPDE putative peptidase domain Thioredoxin PF00085.20 KKK13358.1 - 2.1e-15 56.6 0.0 3.8e-15 55.8 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin TraF PF13728.6 KKK13358.1 - 8.8e-05 22.4 0.0 0.00016 21.6 0.0 1.3 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_2 PF13098.6 KKK13358.1 - 0.0024 18.3 0.3 0.015 15.7 0.3 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_3 PF13192.6 KKK13358.1 - 0.006 16.6 0.0 0.013 15.5 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin domain AhpC-TSA PF00578.21 KKK13358.1 - 0.0077 16.1 0.0 0.014 15.3 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family OST3_OST6 PF04756.13 KKK13358.1 - 0.027 13.8 0.0 0.044 13.1 0.0 1.3 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family Redoxin PF08534.10 KKK13358.1 - 0.038 13.7 0.1 0.092 12.5 0.1 1.6 1 0 0 1 1 1 0 Redoxin DUF2847 PF11009.8 KKK13358.1 - 0.062 13.2 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2847) CxC5 PF18718.1 KKK13358.1 - 0.078 13.1 0.1 3.6 7.7 0.0 2.6 3 0 0 3 3 2 0 CxC5 like cysteine cluster associated with KDZ transposases SAP130_C PF16014.5 KKK13358.1 - 0.23 10.5 3.1 0.36 9.9 3.1 1.2 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP130 C-terminus Alb1 PF09135.11 KKK13359.1 - 4.1e-31 108.0 15.4 6.4e-31 107.3 15.4 1.3 1 0 0 1 1 1 1 Alb1 DUF4201 PF13870.6 KKK13359.1 - 0.013 15.3 1.5 0.017 14.9 1.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) Vps16_C PF04840.12 KKK13360.1 - 4.4e-87 292.1 0.0 1.1e-86 290.8 0.0 1.7 2 0 0 2 2 2 1 Vps16, C-terminal region Vps16_N PF04841.13 KKK13360.1 - 3.4e-70 236.9 0.0 7.7e-70 235.7 0.0 1.6 1 1 0 1 1 1 1 Vps16, N-terminal region AAA_26 PF13500.6 KKK13360.1 - 0.0053 16.6 0.0 0.011 15.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain TruB_C PF09142.11 KKK13360.1 - 0.073 12.9 0.0 2 8.3 0.0 2.5 2 0 0 2 2 2 0 tRNA Pseudouridine synthase II, C terminal Pkinase PF00069.25 KKK13362.1 - 4.2e-67 226.3 1.3 3.9e-66 223.1 1.3 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK13362.1 - 8.7e-52 176.0 0.1 1.5e-51 175.2 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 KKK13362.1 - 4.6e-24 84.5 0.1 5.9e-23 81.0 0.0 2.5 2 0 0 2 2 2 1 P21-Rho-binding domain PH_11 PF15413.6 KKK13362.1 - 3.4e-15 56.3 0.0 1.1e-14 54.7 0.0 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 KKK13362.1 - 1e-06 29.2 0.0 2.4e-06 28.0 0.0 1.7 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.6 KKK13362.1 - 4.2e-06 26.3 0.0 7.5e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KKK13362.1 - 3.2e-05 23.1 0.2 7.3e-05 21.9 0.2 1.6 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 KKK13362.1 - 4.8e-05 22.3 0.0 4.8e-05 22.3 0.0 2.2 3 0 0 3 3 3 1 Fungal protein kinase KIND PF16474.5 KKK13362.1 - 0.011 15.7 3.3 0.1 12.5 0.0 2.4 2 0 0 2 2 2 0 Kinase non-catalytic C-lobe domain Seadorna_VP7 PF07387.11 KKK13362.1 - 0.021 13.9 0.1 0.04 13.0 0.1 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.23 KKK13362.1 - 0.098 12.6 0.3 0.098 12.6 0.3 2.7 2 1 1 3 3 3 0 Phosphotransferase enzyme family NAD_kinase PF01513.21 KKK13363.1 - 7.9e-47 159.8 0.0 3.9e-46 157.6 0.0 1.7 1 1 0 1 1 1 1 ATP-NAD kinase Acyltransferase PF01553.21 KKK13364.1 - 4.7e-27 94.2 0.0 6.7e-27 93.7 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 KKK13364.1 - 1.6e-12 47.4 0.0 3.4e-12 46.3 0.0 1.6 1 0 0 1 1 1 1 Acyltransferase C-terminus TPR_2 PF07719.17 KKK13365.1 - 1.8e-28 96.3 27.7 0.0006 19.7 0.1 12.0 12 0 0 12 12 11 8 Tetratricopeptide repeat TPR_1 PF00515.28 KKK13365.1 - 1.1e-26 91.6 17.5 8.5e-05 22.2 0.0 10.9 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_8 PF13181.6 KKK13365.1 - 8.7e-20 69.2 21.6 0.00052 20.0 0.0 11.5 12 0 0 12 12 12 5 Tetratricopeptide repeat TPR_19 PF14559.6 KKK13365.1 - 3.9e-16 59.3 18.7 0.0072 16.8 0.0 8.8 6 3 3 9 9 9 5 Tetratricopeptide repeat TPR_14 PF13428.6 KKK13365.1 - 2.9e-15 55.6 31.4 0.041 14.7 0.3 12.4 12 1 1 13 13 12 4 Tetratricopeptide repeat TPR_6 PF13174.6 KKK13365.1 - 1.2e-09 38.1 25.5 0.59 10.9 0.1 12.7 13 0 0 13 13 13 2 Tetratricopeptide repeat TPR_16 PF13432.6 KKK13365.1 - 4.4e-09 36.8 27.3 0.03 15.0 0.9 9.0 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_12 PF13424.6 KKK13365.1 - 1.3e-07 31.8 30.0 0.078 13.3 1.3 9.3 7 3 2 9 9 8 4 Tetratricopeptide repeat TPR_11 PF13414.6 KKK13365.1 - 8.7e-07 28.5 20.8 0.21 11.3 0.1 8.3 8 1 1 9 9 9 4 TPR repeat TPR_7 PF13176.6 KKK13365.1 - 2.3e-06 27.2 25.9 0.00037 20.3 0.4 9.2 11 0 0 11 11 10 2 Tetratricopeptide repeat TPR_17 PF13431.6 KKK13365.1 - 6.1e-06 26.3 15.6 2.1 8.9 0.0 9.0 12 0 0 12 12 9 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KKK13365.1 - 0.00051 20.2 8.1 0.39 11.0 0.2 5.7 5 0 0 5 5 5 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 KKK13365.1 - 0.54 10.2 32.5 0.18 11.7 0.2 8.3 9 0 0 9 9 9 0 Tetratricopeptide repeat BAR PF03114.18 KKK13366.1 - 2.5e-65 220.5 4.3 3.1e-65 220.2 4.3 1.1 1 0 0 1 1 1 1 BAR domain CP12 PF02672.15 KKK13366.1 - 0.025 15.3 0.0 0.13 13.1 0.0 2.3 1 1 0 1 1 1 0 CP12 domain DUF2884 PF11101.8 KKK13366.1 - 0.27 10.7 3.1 3 7.3 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2884) SVIP PF15811.5 KKK13366.1 - 3.9 8.0 7.1 0.36 11.3 1.3 2.2 2 1 0 2 2 2 0 Small VCP/p97-interacting protein Jnk-SapK_ap_N PF09744.9 KKK13366.1 - 9.1 6.5 12.2 30 4.8 6.9 3.1 2 2 0 2 2 2 0 JNK_SAPK-associated protein-1 Brix PF04427.18 KKK13367.1 - 2.1e-21 76.9 0.0 1.4e-20 74.3 0.0 2.1 1 1 1 2 2 2 1 Brix domain CDC45 PF02724.14 KKK13367.1 - 0.014 13.8 11.2 0.017 13.5 11.2 1.2 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.10 KKK13367.1 - 0.14 11.5 21.2 0.21 10.9 21.2 1.2 1 0 0 1 1 1 0 BUD22 Sporozoite_P67 PF05642.11 KKK13367.1 - 0.2 9.7 6.5 0.27 9.3 6.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Nop14 PF04147.12 KKK13367.1 - 1.2 7.3 18.3 1.5 6.9 18.3 1.1 1 0 0 1 1 1 0 Nop14-like family GREB1 PF15782.5 KKK13367.1 - 1.7 5.6 3.9 2.2 5.3 3.9 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer HGTP_anticodon PF03129.20 KKK13368.1 - 9.7e-19 67.3 2.1 1.2e-18 67.0 0.0 2.3 3 0 0 3 3 3 1 Anticodon binding domain tRNA-synt_2b PF00587.25 KKK13368.1 - 0.0017 18.4 0.0 0.0095 15.9 0.0 2.1 2 1 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) Spt20 PF12090.8 KKK13368.1 - 0.22 11.1 3.5 0.42 10.2 3.5 1.4 1 0 0 1 1 1 0 Spt20 family Band_7 PF01145.25 KKK13368.1 - 8.6 6.3 6.4 2.7 8.0 0.4 2.5 2 0 0 2 2 2 0 SPFH domain / Band 7 family Sybindin PF04099.12 KKK13369.1 - 8.3e-26 90.6 0.0 1.1e-25 90.3 0.0 1.1 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 KKK13369.1 - 0.0034 17.5 0.2 0.0048 17.0 0.2 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Pkinase PF00069.25 KKK13370.1 - 4.2e-49 167.3 0.0 7.4e-49 166.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK13370.1 - 3.8e-27 95.2 0.0 5.5e-27 94.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KKK13370.1 - 0.0021 17.4 0.0 0.0035 16.7 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KKK13370.1 - 0.003 16.9 0.0 0.006 16.0 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KKK13370.1 - 0.1 12.5 0.4 0.85 9.5 0.0 2.4 2 1 1 3 3 3 0 Phosphotransferase enzyme family Pept_tRNA_hydro PF01195.19 KKK13371.1 - 1.3e-19 70.8 0.0 1.5e-11 44.5 0.0 3.0 2 1 0 2 2 2 2 Peptidyl-tRNA hydrolase SRI PF08236.11 KKK13372.1 - 8.6e-21 73.9 15.4 2e-20 72.7 15.4 1.7 1 0 0 1 1 1 1 SRI (Set2 Rpb1 interacting) domain SET PF00856.28 KKK13372.1 - 1.8e-16 61.0 4.2 2.4e-16 60.6 0.3 3.0 2 1 0 2 2 2 1 SET domain AWS PF17907.1 KKK13372.1 - 3.2e-10 39.9 9.4 3.2e-10 39.9 9.4 2.3 2 0 0 2 2 2 1 AWS domain WW PF00397.26 KKK13372.1 - 0.016 15.3 0.7 0.048 13.8 0.7 1.9 1 0 0 1 1 1 0 WW domain Pox_H7 PF04787.12 KKK13372.1 - 0.27 11.7 3.3 0.55 10.7 3.3 1.4 1 0 0 1 1 1 0 Late protein H7 eIF-6 PF01912.18 KKK13373.1 - 1.4e-75 253.1 0.2 1.6e-75 252.8 0.2 1.0 1 0 0 1 1 1 1 eIF-6 family Pkinase PF00069.25 KKK13374.1 - 1.5e-53 181.9 0.1 3.9e-48 164.1 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KKK13374.1 - 1.2e-33 116.5 0.1 3.1e-32 111.9 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 KKK13374.1 - 8.9e-08 31.8 0.0 2e-07 30.6 0.0 1.5 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KKK13374.1 - 0.0031 17.5 0.1 0.0066 16.4 0.1 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KKK13374.1 - 0.0068 15.2 0.0 0.016 14.0 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase AT_hook PF02178.19 KKK13375.1 - 0.025 14.4 1.5 0.025 14.4 1.5 2.8 2 0 0 2 2 2 0 AT hook motif Peptidase_M24 PF00557.24 KKK13376.1 - 2.3e-44 151.6 0.1 7.3e-42 143.4 0.1 2.2 1 1 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 KKK13376.1 - 5.4e-24 84.3 0.0 1e-23 83.4 0.0 1.5 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain DnaJ PF00226.31 KKK13377.1 - 5.5e-17 61.7 0.7 1.5e-16 60.2 0.7 1.8 1 0 0 1 1 1 1 DnaJ domain Sec63 PF02889.16 KKK13377.1 - 8.9e-13 48.0 0.0 4.8e-08 32.5 0.0 2.2 2 0 0 2 2 2 2 Sec63 Brl domain DUF3157 PF11355.8 KKK13378.1 - 0.051 13.2 0.0 0.083 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3157) Ribonucleas_3_3 PF14622.6 KKK13380.1 - 9.4e-29 100.2 0.0 1.7e-28 99.4 0.0 1.4 1 1 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 KKK13380.1 - 1.5e-08 35.2 0.0 5.2e-08 33.5 0.0 1.9 2 1 0 2 2 2 1 Ribonuclease III domain Sdh_cyt PF01127.22 KKK13381.1 - 2.8e-25 88.7 3.2 4.5e-25 88.0 3.2 1.3 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit TAL_FSA PF00923.19 KKK13382.1 - 6.5e-50 170.1 0.0 7.8e-50 169.8 0.0 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase Cation_efflux PF01545.21 KKK13383.1 - 7.7e-62 208.6 5.9 1e-61 208.2 5.9 1.2 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 KKK13383.1 - 1.9e-06 27.9 0.3 6e-06 26.3 0.0 2.0 2 0 0 2 2 2 1 Dimerisation domain of Zinc Transporter DUF808 PF05661.12 KKK13383.1 - 0.13 11.3 4.0 0.046 12.8 0.5 2.0 3 0 0 3 3 3 0 Protein of unknown function (DUF808) Citrate_synt PF00285.21 KKK13385.1 - 9.8e-101 337.4 0.0 1.3e-100 337.0 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain S8_pro-domain PF16470.5 KKK13385.1 - 0.13 13.1 0.2 2 9.2 0.1 2.4 2 0 0 2 2 2 0 Peptidase S8 pro-domain RRM_1 PF00076.22 KKK13386.1 - 2.9e-05 23.8 0.0 4.7e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CTD_bind PF04818.13 KKK13386.1 - 0.0001 23.0 0.0 0.00022 22.0 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase II-binding domain. Mito_carr PF00153.27 KKK13387.1 - 4.7e-28 96.9 4.7 6.8e-13 48.4 0.0 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein MMS19_N PF14500.6 KKK13388.1 - 1.2e-93 313.5 0.4 2.8e-93 312.3 0.1 1.9 2 0 0 2 2 2 1 Dos2-interacting transcription regulator of RNA-Pol-II MMS19_C PF12460.8 KKK13388.1 - 8.9e-69 232.6 4.4 1.1e-66 225.7 0.3 3.5 3 1 0 3 3 3 2 RNAPII transcription regulator C-terminal RTP1_C1 PF10363.9 KKK13388.1 - 0.003 17.7 0.5 0.17 12.1 0.0 2.8 2 0 0 2 2 2 1 Required for nuclear transport of RNA pol II C-terminus 1 FANCI_S2 PF14676.6 KKK13388.1 - 5.8 7.2 6.6 6.5 7.0 0.2 3.6 3 2 0 4 4 4 0 FANCI solenoid 2 Fasciclin PF02469.22 KKK13389.1 - 1.5e-06 28.4 0.0 2.4e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Fasciclin domain EMC3_TMCO1 PF01956.16 KKK13390.1 - 8e-52 175.4 1.1 9.7e-52 175.1 1.1 1.1 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like SPC25 PF06703.11 KKK13391.1 - 6.9e-52 175.5 0.1 8.4e-52 175.2 0.1 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) THF_DHG_CYH PF00763.23 KKK13392.1 - 3.4e-24 85.3 0.0 5.1e-24 84.8 0.0 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.19 KKK13392.1 - 1.6e-12 47.1 0.0 1.9e-09 37.1 0.0 2.5 2 1 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain TPP_enzyme_N PF02776.18 KKK13393.1 - 8.9e-47 158.9 0.1 2.5e-45 154.2 0.0 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 KKK13393.1 - 4.5e-38 130.1 0.3 9.5e-38 129.0 0.1 1.7 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 KKK13393.1 - 3.2e-17 62.7 0.1 7.3e-17 61.6 0.1 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain B12-binding PF02310.19 KKK13393.1 - 0.011 15.7 0.3 0.029 14.4 0.3 1.7 1 0 0 1 1 1 0 B12 binding domain CO_dh PF02552.16 KKK13393.1 - 0.2 11.4 0.0 0.33 10.7 0.0 1.3 1 0 0 1 1 1 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit TPR_1 PF00515.28 KKK13394.1 - 1e-23 82.1 2.7 2.8e-08 33.2 0.1 5.8 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 KKK13394.1 - 3.1e-23 80.0 2.5 1.8e-07 30.7 0.1 5.9 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_11 PF13414.6 KKK13394.1 - 8.1e-20 70.2 2.6 5.3e-09 35.6 0.1 4.9 4 1 1 5 5 5 3 TPR repeat TPR_16 PF13432.6 KKK13394.1 - 1.4e-18 67.3 2.7 1.2e-05 25.8 0.0 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 KKK13394.1 - 1.6e-16 59.6 1.1 8.2e-05 23.1 0.0 5.7 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.6 KKK13394.1 - 1.3e-14 53.4 1.8 0.0078 16.5 0.1 5.0 5 0 0 5 5 4 4 Tetratricopeptide repeat TPR_19 PF14559.6 KKK13394.1 - 1.1e-13 51.4 2.8 0.00048 20.6 0.0 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 KKK13394.1 - 6.1e-13 47.9 0.8 2.8e-06 27.1 0.0 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 KKK13394.1 - 8.9e-12 44.2 1.5 0.0069 16.3 0.0 6.4 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_12 PF13424.6 KKK13394.1 - 1.2e-11 44.7 2.1 7.8e-07 29.3 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_20 PF14561.6 KKK13394.1 - 5.3e-11 42.7 0.2 0.008 16.5 0.0 4.7 2 2 2 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 KKK13394.1 - 2.1e-08 34.2 1.0 0.0024 18.0 0.1 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 KKK13394.1 - 1.7e-06 28.3 1.6 1.2 10.0 0.0 6.1 6 0 0 6 6 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KKK13394.1 - 6.2e-06 26.4 1.4 0.0008 19.6 0.1 2.7 2 1 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 KKK13394.1 - 0.0004 19.7 0.6 0.49 9.6 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_3 PF07720.12 KKK13394.1 - 0.00093 19.1 0.1 0.16 12.0 0.0 3.1 3 0 0 3 3 2 1 Tetratricopeptide repeat MIT PF04212.18 KKK13394.1 - 0.0021 18.1 0.5 4.9 7.3 0.1 4.0 4 0 0 4 4 4 1 MIT (microtubule interacting and transport) domain TPR_10 PF13374.6 KKK13394.1 - 0.0096 15.8 6.2 0.064 13.2 0.9 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat NatB_MDM20 PF09797.9 KKK13394.1 - 0.017 14.1 0.0 0.046 12.6 0.0 1.7 2 0 0 2 2 2 0 N-acetyltransferase B complex (NatB) non catalytic subunit DUF1641 PF07849.11 KKK13394.1 - 0.078 12.9 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1641) TOM20_plant PF06552.12 KKK13394.1 - 0.086 12.6 0.1 2.6 7.7 0.0 3.0 3 1 0 3 3 3 0 Plant specific mitochondrial import receptor subunit TOM20 Spt20 PF12090.8 KKK13394.1 - 0.24 11.0 2.0 0.45 10.1 2.0 1.5 1 0 0 1 1 1 0 Spt20 family DUF4192 PF13830.6 KKK13394.1 - 1.2 9.1 7.9 14 5.6 7.9 2.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4192) RRM_1 PF00076.22 KKK13395.1 - 7.4e-32 109.0 0.0 1.7e-18 66.2 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Fungal_trans PF04082.18 KKK13395.1 - 1.6e-13 50.3 0.2 6.2e-13 48.4 0.0 1.9 1 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK13395.1 - 3.4e-06 27.1 11.7 5.8e-06 26.3 11.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HSBP1 PF06825.12 KKK13395.1 - 0.039 13.8 0.3 0.095 12.6 0.3 1.6 1 0 0 1 1 1 0 Heat shock factor binding protein 1 Piwi PF02171.17 KKK13396.1 - 2.7e-70 237.0 0.0 4.2e-70 236.4 0.0 1.3 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 KKK13396.1 - 4.3e-19 69.5 0.0 8.6e-19 68.5 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL2 PF16488.5 KKK13396.1 - 2.5e-10 40.5 0.0 2.2e-09 37.5 0.0 2.4 2 0 0 2 2 2 1 Argonaute linker 2 domain ArgoL1 PF08699.10 KKK13396.1 - 4.6e-10 39.0 0.0 2.7e-09 36.5 0.0 2.2 2 0 0 2 2 2 1 Argonaute linker 1 domain PAZ PF02170.22 KKK13396.1 - 1e-06 28.6 0.0 2e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 PAZ domain ArgoMid PF16487.5 KKK13396.1 - 0.0024 18.1 0.0 0.0053 17.0 0.0 1.6 1 0 0 1 1 1 1 Mid domain of argonaute DUF5320 PF17253.2 KKK13396.1 - 0.092 13.8 16.7 0.25 12.4 16.7 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5320) SHS2_Rpb7-N PF03876.17 KKK13398.1 - 1.5e-14 54.1 0.0 2.9e-14 53.2 0.0 1.5 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 KKK13398.1 - 7.9e-10 38.9 0.0 1.3e-09 38.3 0.0 1.3 1 0 0 1 1 1 1 S1 RNA binding domain DUF962 PF06127.11 KKK13399.1 - 1.7e-24 85.7 0.1 3.5e-24 84.7 0.1 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF962) Osw5 PF17062.5 KKK13399.1 - 0.065 13.3 0.5 0.15 12.1 0.5 1.7 1 0 0 1 1 1 0 Outer spore wall 5 ATP-synt_ab PF00006.25 KKK13400.1 - 1.3e-72 244.0 0.0 2e-72 243.3 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 KKK13400.1 - 5.9e-48 162.4 0.6 1.1e-47 161.5 0.6 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 KKK13400.1 - 9.6e-15 54.9 3.2 2.4e-14 53.6 3.2 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain Zn_clus PF00172.18 KKK13401.1 - 0.00028 20.9 6.3 0.0007 19.7 6.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cep3 PF16846.5 KKK13401.1 - 0.0065 15.0 0.1 0.011 14.3 0.1 1.3 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit B SOR PF07682.11 KKK13401.1 - 0.018 13.9 0.0 0.029 13.3 0.0 1.2 1 0 0 1 1 1 0 Sulphur oxygenase reductase Sld7_C PF18596.1 KKK13401.1 - 0.1 12.8 0.0 1.4 9.1 0.0 2.5 2 0 0 2 2 2 0 Sld7 C-terminal domain Peptidase_M24 PF00557.24 KKK13402.1 - 1.5e-19 70.5 0.0 1.7e-19 70.4 0.0 1.0 1 0 0 1 1 1 1 Metallopeptidase family M24 SH2_2 PF14633.6 KKK13403.1 - 1.6e-85 285.9 0.0 4.4e-85 284.5 0.0 1.8 1 0 0 1 1 1 1 SH2 domain HTH_44 PF14641.6 KKK13403.1 - 2.3e-35 121.5 7.8 3.8e-35 120.8 2.0 2.7 2 0 0 2 2 2 1 Helix-turn-helix DNA-binding domain of SPT6 YqgF PF14639.6 KKK13403.1 - 8.7e-31 106.7 0.1 3.9e-30 104.6 0.0 2.2 2 0 0 2 2 2 1 Holliday-junction resolvase-like of SPT6 HHH_7 PF14635.6 KKK13403.1 - 8.9e-31 106.3 0.0 1.7e-30 105.4 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif SPT6_acidic PF14632.6 KKK13403.1 - 2.8e-17 63.1 27.5 2.8e-17 63.1 27.5 4.9 4 2 1 5 5 5 1 Acidic N-terminal SPT6 HHH_9 PF17674.1 KKK13403.1 - 5.6e-08 33.6 2.3 2.4e-06 28.4 2.6 3.6 2 1 0 2 2 2 1 HHH domain SH2 PF00017.24 KKK13403.1 - 3.2e-05 23.9 0.0 8.4e-05 22.6 0.0 1.8 1 0 0 1 1 1 1 SH2 domain HHH_3 PF12836.7 KKK13403.1 - 0.0047 17.2 0.0 0.011 15.9 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif Tex_N PF09371.10 KKK13403.1 - 0.0073 16.0 7.5 0.076 12.7 0.0 3.9 4 0 0 4 4 4 1 Tex-like protein N-terminal domain Pkinase PF00069.25 KKK13404.1 - 1.4e-64 218.0 0.0 1.8e-64 217.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK13404.1 - 2.2e-36 125.5 0.0 3e-36 125.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KKK13404.1 - 1.2e-05 24.3 0.0 1.8e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KKK13404.1 - 0.00059 19.2 0.0 0.001 18.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 KKK13404.1 - 0.014 14.5 0.0 0.02 13.9 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Haspin_kinase PF12330.8 KKK13404.1 - 0.014 14.3 0.0 0.025 13.6 0.0 1.5 1 1 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 KKK13404.1 - 0.036 14.0 0.0 0.075 12.9 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 KKK13404.1 - 0.073 12.7 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 RIO1 family FAP PF07174.11 KKK13405.1 - 5.8 6.3 10.3 3 7.2 4.4 2.1 2 0 0 2 2 2 0 Fibronectin-attachment protein (FAP) PfkB PF00294.24 KKK13411.1 - 3.4e-70 236.7 0.1 3.9e-70 236.5 0.1 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 KKK13411.1 - 0.014 14.7 0.0 0.029 13.8 0.0 1.4 1 0 0 1 1 1 0 Phosphomethylpyrimidine kinase DUF1770 PF08589.10 KKK13412.1 - 3.3e-21 76.1 1.7 9.1e-21 74.7 0.7 2.1 2 1 0 2 2 2 1 Fungal protein of unknown function (DUF1770) EST1_DNA_bind PF10373.9 KKK13414.1 - 2.2e-70 237.4 0.1 4.9e-70 236.2 0.1 1.5 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain EST1 PF10374.9 KKK13414.1 - 4.1e-24 85.8 0.2 1.2e-23 84.2 0.1 1.9 2 0 0 2 2 2 1 Telomerase activating protein Est1 Ada_Zn_binding PF02805.16 KKK13415.1 - 1.1e-30 105.4 5.1 1.9e-30 104.6 5.1 1.4 1 0 0 1 1 1 1 Metal binding domain of Ada HTH_AraC PF00165.23 KKK13415.1 - 1.9e-07 31.0 0.0 5.1e-07 29.6 0.0 1.7 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_18 PF12833.7 KKK13415.1 - 0.00063 20.0 0.0 0.0013 18.9 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain BAR PF03114.18 KKK13416.1 - 2.4e-49 168.2 8.2 3.1e-49 167.8 8.2 1.1 1 0 0 1 1 1 1 BAR domain BAR_2 PF10455.9 KKK13416.1 - 1.8e-07 30.6 3.6 2.3e-07 30.3 3.6 1.2 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking Apo-CIII PF05778.12 KKK13416.1 - 0.011 15.3 0.1 0.031 13.9 0.1 1.7 1 0 0 1 1 1 0 Apolipoprotein CIII (Apo-CIII) Ribosomal_S10 PF00338.22 KKK13416.1 - 0.042 14.1 0.4 0.11 12.8 0.4 1.7 1 0 0 1 1 1 0 Ribosomal protein S10p/S20e APG6_N PF17675.1 KKK13416.1 - 3.9 8.0 13.1 12 6.4 13.1 1.9 1 1 0 1 1 1 0 Apg6 coiled-coil region WHIM1 PF15612.6 KKK13417.1 - 1.1e-06 28.1 0.0 2.4e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 Ribosomal_L2_C PF03947.18 KKK13418.1 - 1.1e-28 100.0 7.3 2e-24 86.2 3.7 2.4 1 1 1 2 2 2 2 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 KKK13418.1 - 8.8e-15 54.4 0.1 2.3e-14 53.1 0.1 1.7 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain SNF2_N PF00176.23 KKK13419.1 - 2.3e-73 246.9 0.7 2.3e-73 246.9 0.7 2.3 2 0 0 2 2 2 1 SNF2 family N-terminal domain Bromodomain PF00439.25 KKK13419.1 - 1.6e-25 88.9 1.2 7.8e-25 86.8 0.4 2.6 2 1 0 2 2 2 1 Bromodomain Helicase_C PF00271.31 KKK13419.1 - 3.8e-20 72.3 1.4 3e-18 66.2 0.0 3.6 3 1 1 4 4 4 1 Helicase conserved C-terminal domain HSA PF07529.13 KKK13419.1 - 3.9e-19 68.7 17.4 3.9e-19 68.7 17.4 3.2 3 0 0 3 3 3 1 HSA SnAC PF14619.6 KKK13419.1 - 5.1e-16 59.0 2.5 5.1e-16 59.0 2.5 3.4 3 0 0 3 3 3 1 Snf2-ATP coupling, chromatin remodelling complex QLQ PF08880.11 KKK13419.1 - 1.2e-13 50.6 3.9 1.2e-13 50.6 3.9 2.1 2 0 0 2 2 2 1 QLQ ResIII PF04851.15 KKK13419.1 - 4e-09 36.7 0.0 4e-09 36.7 0.0 2.4 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Fungal_trans PF04082.18 KKK13420.1 - 9.1e-15 54.4 1.2 9.1e-15 54.4 1.2 1.9 2 1 0 2 2 2 1 Fungal specific transcription factor domain Pkinase PF00069.25 KKK13421.1 - 8.7e-69 231.8 0.0 8e-68 228.6 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK13421.1 - 3e-49 167.6 0.0 1.8e-47 161.8 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Ras_bdg_2 PF14847.6 KKK13421.1 - 5.7e-28 97.2 0.0 1e-27 96.4 0.0 1.4 1 0 0 1 1 1 1 Ras-binding domain of Byr2 SAM_1 PF00536.30 KKK13421.1 - 3.2e-14 53.1 0.1 8.3e-14 51.8 0.1 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KKK13421.1 - 2e-11 43.8 0.1 5.4e-11 42.4 0.1 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Kinase-like PF14531.6 KKK13421.1 - 2.4e-08 33.7 0.0 4e-05 23.1 0.0 2.4 2 0 0 2 2 2 2 Kinase-like RA PF00788.23 KKK13421.1 - 8.6e-07 29.5 0.0 1.5e-06 28.7 0.0 1.4 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Pkinase_fungal PF17667.1 KKK13421.1 - 0.0011 17.9 0.0 0.0019 17.1 0.0 1.5 1 1 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KKK13421.1 - 0.046 13.1 0.0 0.094 12.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SAM_4 PF18017.1 KKK13421.1 - 0.055 13.5 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) MSA-2c PF12238.8 KKK13421.1 - 0.58 10.1 0.0 0.58 10.1 0.0 2.3 3 0 0 3 3 3 0 Merozoite surface antigen 2c SNF2_N PF00176.23 KKK13422.1 - 4.7e-44 150.5 0.1 6.5e-44 150.1 0.1 1.1 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-C3HC4_3 PF13920.6 KKK13422.1 - 4e-07 29.8 5.4 7.9e-07 28.8 5.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KKK13422.1 - 0.00042 20.1 5.1 0.00089 19.1 5.1 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KKK13422.1 - 0.00074 19.4 8.1 0.0019 18.1 8.1 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 KKK13422.1 - 0.021 15.2 7.0 0.049 14.0 7.0 1.7 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4 PF00097.25 KKK13422.1 - 0.026 14.4 10.0 0.063 13.2 10.0 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) VPS53_C PF16854.5 KKK13422.1 - 0.088 12.7 0.2 0.16 11.8 0.2 1.4 1 0 0 1 1 1 0 Vacuolar protein sorting-associated protein 53 C-terminus ResIII PF04851.15 KKK13422.1 - 0.11 12.5 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit zf-RING_UBOX PF13445.6 KKK13422.1 - 0.14 12.2 6.7 0.34 11.0 6.7 1.7 1 0 0 1 1 1 0 RING-type zinc-finger Dak1_2 PF13684.6 KKK13422.1 - 0.69 8.9 1.5 1.7 7.6 1.5 1.6 1 0 0 1 1 1 0 Dihydroxyacetone kinase family zf-C3HC4_2 PF13923.6 KKK13422.1 - 2 8.3 9.6 0.087 12.7 3.5 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) SNF2_N PF00176.23 KKK13494.1 - 4.2e-37 127.7 0.0 2.3e-33 115.4 0.0 2.2 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 KKK13494.1 - 3.8e-09 36.9 0.1 7.2e-09 36.0 0.1 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain MOSC PF03473.17 KKK13496.1 - 1.6e-32 112.2 0.0 2.8e-32 111.5 0.0 1.4 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 KKK13496.1 - 3.2e-30 104.5 0.0 5.6e-30 103.7 0.0 1.4 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain Aminotran_5 PF00266.19 KKK13496.1 - 1.4e-20 73.7 0.0 2.5e-20 72.8 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class-V ERAP1_C PF11838.8 KKK13497.1 - 8.1e-90 301.5 0.2 1.9e-88 297.0 0.2 2.4 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_M1 PF01433.20 KKK13497.1 - 1e-80 270.4 0.2 1.7e-80 269.7 0.2 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 KKK13497.1 - 2.5e-56 190.8 2.1 4.2e-56 190.1 2.1 1.4 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain DUF2808 PF10989.8 KKK13497.1 - 0.0031 17.5 0.1 0.006 16.6 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2808) DUF3543 PF12063.8 KKK13498.1 - 1.1e-94 316.6 0.0 1.6e-94 316.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) Pkinase PF00069.25 KKK13498.1 - 1.8e-63 214.4 0.0 3.1e-63 213.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK13498.1 - 4.4e-44 150.7 0.0 6.2e-44 150.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KKK13498.1 - 0.0082 15.0 0.0 0.014 14.2 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase TAF8_C PF10406.9 KKK13498.1 - 0.014 16.0 0.2 0.055 14.0 0.2 2.1 1 0 0 1 1 1 0 Transcription factor TFIID complex subunit 8 C-term HAT PF02184.16 KKK13500.1 - 0.073 13.0 0.0 5.4 7.1 0.3 2.6 2 1 0 2 2 2 0 HAT (Half-A-TPR) repeat Mitoc_mL59 PF18126.1 KKK13501.1 - 3.9e-46 156.5 12.6 1.5e-45 154.6 12.6 1.8 1 1 0 1 1 1 1 Mitochondrial ribosomal protein mL59 Ribonuc_L-PSP PF01042.21 KKK13502.1 - 9.8e-17 61.1 0.0 3.8e-07 30.1 0.0 3.3 3 0 0 3 3 3 3 Endoribonuclease L-PSP ABC2_membrane PF01061.24 KKK13517.1 - 2.1e-68 229.9 45.5 3.3e-40 137.8 16.8 2.6 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 KKK13517.1 - 8e-38 130.1 2.6 5.6e-20 72.3 0.0 3.2 4 0 0 4 4 3 2 ABC transporter PDR_CDR PF06422.12 KKK13517.1 - 2.2e-26 91.6 0.0 2.2e-26 91.6 0.0 2.5 2 0 0 2 2 1 1 CDR ABC transporter ABC_trans_N PF14510.6 KKK13517.1 - 1e-14 54.9 0.2 3.5e-14 53.2 0.2 2.0 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_16 PF13191.6 KKK13517.1 - 5.1e-06 27.0 0.1 0.0023 18.3 0.1 2.6 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 KKK13517.1 - 9.3e-06 25.6 0.0 0.0012 18.8 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_18 PF13238.6 KKK13517.1 - 1.7e-05 25.4 0.0 0.00064 20.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 KKK13517.1 - 2.5e-05 24.3 0.0 0.092 12.8 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_21 PF13304.6 KKK13517.1 - 3.2e-05 23.9 0.0 0.041 13.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KKK13517.1 - 0.00018 21.2 0.5 0.47 10.2 0.2 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_24 PF13479.6 KKK13517.1 - 0.00031 20.5 0.0 0.1 12.3 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.6 KKK13517.1 - 0.00034 20.9 0.0 0.036 14.4 0.0 3.3 3 0 0 3 3 2 1 AAA domain AAA_28 PF13521.6 KKK13517.1 - 0.00036 20.8 0.0 0.0025 18.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KKK13517.1 - 0.00053 19.6 0.0 0.53 9.8 0.2 2.9 2 0 0 2 2 2 1 AAA domain ABC2_membrane_3 PF12698.7 KKK13517.1 - 0.00066 18.9 12.4 0.00066 18.9 12.4 2.7 3 0 0 3 3 2 1 ABC-2 family transporter protein cobW PF02492.19 KKK13517.1 - 0.0013 18.3 0.1 0.034 13.7 0.1 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 KKK13517.1 - 0.0021 18.0 0.3 0.22 11.4 0.2 2.6 2 0 0 2 2 2 1 NACHT domain SMC_N PF02463.19 KKK13517.1 - 0.0036 16.8 1.0 0.065 12.7 0.1 3.0 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_33 PF13671.6 KKK13517.1 - 0.0052 17.0 6.7 0.011 15.9 0.0 3.1 4 0 0 4 4 2 1 AAA domain AAA_30 PF13604.6 KKK13517.1 - 0.043 13.5 1.2 3.8 7.2 0.6 2.4 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 KKK13517.1 - 0.06 13.4 0.2 2.7 8.0 0.0 3.2 3 0 0 3 3 3 0 Dynamin family AAA PF00004.29 KKK13517.1 - 0.064 13.7 0.0 22 5.5 0.1 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Septin PF00735.18 KKK13517.1 - 0.07 12.4 0.1 0.42 9.8 0.1 2.0 2 0 0 2 2 2 0 Septin TsaE PF02367.17 KKK13517.1 - 0.071 13.1 0.3 0.81 9.7 0.2 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NB-ARC PF00931.22 KKK13517.1 - 0.073 12.2 0.4 2.9 7.0 0.1 2.6 3 0 0 3 3 2 0 NB-ARC domain FtsK_SpoIIIE PF01580.18 KKK13517.1 - 0.099 12.0 0.1 6 6.2 0.1 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family MCM PF00493.23 KKK13517.1 - 0.14 11.3 0.0 3.5 6.7 0.0 2.4 2 0 0 2 2 2 0 MCM P-loop domain Zeta_toxin PF06414.12 KKK13517.1 - 0.21 10.8 1.1 1.4 8.1 0.5 2.2 2 0 0 2 2 2 0 Zeta toxin SLATT_5 PF18160.1 KKK13517.1 - 6.7 6.0 5.8 1.6 8.0 0.2 2.8 2 1 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 Epimerase PF01370.21 KKK13525.1 - 5.8e-17 62.0 0.0 8.7e-17 61.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KKK13525.1 - 1.7e-08 33.8 0.0 2e-07 30.3 0.0 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KKK13525.1 - 7.8e-05 22.2 0.0 0.00057 19.4 0.0 2.0 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase Ldh_1_N PF00056.23 KKK13525.1 - 0.027 14.6 0.0 0.055 13.6 0.0 1.5 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain KR PF08659.10 KKK13525.1 - 0.074 13.0 0.0 0.27 11.1 0.0 1.9 2 1 0 2 2 2 0 KR domain Dioxygenase_N PF04444.14 KKK13526.1 - 0.11 12.4 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Catechol dioxygenase N terminus Vta1 PF04652.16 KKK13527.1 - 6.9e-48 162.3 0.1 1.9e-47 160.9 0.1 1.7 1 1 0 1 1 1 1 Vta1 like Vta1_C PF18097.1 KKK13527.1 - 1.2e-15 56.9 0.2 2.4e-15 56.0 0.2 1.5 1 0 0 1 1 1 1 Vta1 C-terminal domain MSA_2 PF00985.17 KKK13527.1 - 0.042 14.2 1.8 0.042 14.2 1.8 2.0 1 1 2 3 3 3 0 Merozoite Surface Antigen 2 (MSA-2) family Mito_carr PF00153.27 KKK13528.1 - 2.3e-53 178.1 1.6 1.1e-20 73.3 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Peptidase_C2 PF00648.21 KKK13529.1 - 1.6e-29 102.9 0.0 3.7e-29 101.7 0.0 1.6 1 1 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 KKK13529.1 - 5e-08 33.3 0.0 4.9e-05 23.6 0.0 3.7 3 1 0 3 3 3 1 Calpain large subunit, domain III MIT PF04212.18 KKK13529.1 - 0.00044 20.3 0.8 0.00073 19.6 0.8 1.3 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain BSMAP PF12280.8 KKK13530.1 - 0.024 14.9 0.0 0.031 14.5 0.0 1.1 1 0 0 1 1 1 0 Brain specific membrane anchored protein DUF1793 PF08760.11 KKK13531.1 - 3.6e-70 235.7 0.8 5.1e-70 235.2 0.1 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF1793) DUF4965 PF16335.5 KKK13531.1 - 2e-63 213.2 1.0 1.3e-49 168.2 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF4965) DUF5127 PF17168.4 KKK13531.1 - 6.5e-48 163.5 0.2 1.1e-47 162.7 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) DUF4964 PF16334.5 KKK13531.1 - 0.0064 16.0 0.0 0.015 14.9 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4964) BSP_II PF05432.11 KKK13533.1 - 6.2e-05 22.8 12.6 7.3e-05 22.6 12.6 1.1 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) eIF-3c_N PF05470.12 KKK13533.1 - 0.018 13.4 6.6 0.019 13.3 6.6 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus SDA1 PF05285.12 KKK13533.1 - 0.032 13.7 12.1 0.038 13.4 12.1 1.1 1 0 0 1 1 1 0 SDA1 SURF2 PF05477.11 KKK13533.1 - 0.037 13.7 12.1 0.044 13.5 12.1 1.1 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) TFIIF_alpha PF05793.12 KKK13533.1 - 0.052 12.1 11.7 0.062 11.9 11.7 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SRP-alpha_N PF04086.13 KKK13533.1 - 0.06 13.3 12.4 0.075 13.0 12.4 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal CDC45 PF02724.14 KKK13533.1 - 0.2 9.9 13.6 0.24 9.6 13.6 1.1 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 KKK13533.1 - 0.87 7.6 18.4 1 7.4 18.4 1.0 1 0 0 1 1 1 0 DNA polymerase phi Sporozoite_P67 PF05642.11 KKK13533.1 - 0.89 7.6 6.7 1.2 7.2 6.7 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF4551 PF15087.6 KKK13533.1 - 1.2 7.9 10.0 1.3 7.8 10.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) ORC6 PF05460.13 KKK13533.1 - 1.5 8.0 13.3 2 7.6 13.3 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) RR_TM4-6 PF06459.12 KKK13533.1 - 1.9 8.3 14.1 2.9 7.7 14.1 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Presenilin PF01080.17 KKK13533.1 - 1.9 7.2 13.7 2.2 6.9 13.7 1.1 1 0 0 1 1 1 0 Presenilin SLC12 PF03522.15 KKK13533.1 - 2.3 7.1 10.1 2.8 6.9 10.1 1.0 1 0 0 1 1 1 0 Solute carrier family 12 Neur_chan_memb PF02932.16 KKK13533.1 - 2.7 8.0 6.3 3.4 7.7 6.3 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Hid1 PF12722.7 KKK13533.1 - 2.8 6.0 14.2 3.3 5.7 14.2 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Endostatin PF06482.11 KKK13533.1 - 3.4 7.0 10.4 4.1 6.8 10.4 1.1 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin Plasmodium_Vir PF05795.11 KKK13533.1 - 3.8 6.8 8.7 4.4 6.6 8.7 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein SAPS PF04499.15 KKK13533.1 - 5 5.8 10.8 5.4 5.7 10.8 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DEAD PF00270.29 KKK13534.1 - 5.4e-42 143.5 0.0 9.4e-42 142.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KKK13534.1 - 9.4e-29 100.0 0.0 2.6e-28 98.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KKK13534.1 - 7.1e-06 26.1 0.0 1.3e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HCO3_cotransp PF00955.21 KKK13535.1 - 8.5e-86 288.8 11.3 1e-46 159.9 5.1 2.1 1 1 1 2 2 2 2 HCO3- transporter family zf-CCHC PF00098.23 KKK13536.1 - 2.1e-12 46.5 11.1 7.5e-06 25.8 0.8 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_3 PF13917.6 KKK13536.1 - 5.8e-07 29.4 5.7 0.00072 19.5 2.8 2.3 1 1 1 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.6 KKK13536.1 - 0.00058 19.5 5.0 0.24 11.1 0.4 2.2 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_6 PF15288.6 KKK13536.1 - 0.006 16.4 12.5 0.2 11.5 0.6 3.6 3 0 0 3 3 3 2 Zinc knuckle zf-CCHC_2 PF13696.6 KKK13536.1 - 0.0081 16.0 0.5 0.0081 16.0 0.5 2.5 2 0 0 2 2 2 1 Zinc knuckle C1_2 PF03107.16 KKK13536.1 - 1.3 9.3 3.8 1.1 9.6 1.8 1.8 1 1 1 2 2 2 0 C1 domain SPX PF03105.19 KKK13537.1 - 0.52 10.2 4.7 1.1 9.1 1.9 2.1 2 0 0 2 2 2 0 SPX domain DUF3237 PF11578.8 KKK13565.1 - 3.4e-34 117.8 0.0 3.9e-34 117.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) adh_short PF00106.25 KKK13566.1 - 2.8e-23 82.4 0.0 1.2e-19 70.5 0.0 2.0 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KKK13566.1 - 1.4e-12 47.7 0.1 1.2e-11 44.7 0.1 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KKK13566.1 - 0.00053 20.0 0.1 0.00081 19.3 0.1 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KKK13566.1 - 0.01 15.0 0.0 0.015 14.5 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein THUMP PF02926.17 KKK13567.1 - 2.6e-12 47.1 1.1 5e-12 46.1 0.2 1.8 2 0 0 2 2 2 1 THUMP domain TPP_enzyme_N PF02776.18 KKK13568.1 - 1.9e-32 112.2 0.0 3.3e-32 111.5 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 KKK13568.1 - 3e-22 78.8 0.0 5.9e-22 77.9 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 KKK13568.1 - 5.3e-15 55.5 0.0 1.7e-14 53.9 0.0 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.20 KKK13568.1 - 0.0061 15.5 0.1 0.011 14.8 0.1 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component GMC_oxred_N PF00732.19 KKK13570.1 - 1.7e-51 175.3 0.0 2.4e-51 174.9 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KKK13570.1 - 3.3e-33 115.2 0.0 5.5e-33 114.5 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.24 KKK13570.1 - 3.3e-05 23.6 0.0 0.00014 21.6 0.0 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KKK13570.1 - 6.8e-05 22.1 0.0 0.13 11.3 0.2 2.3 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KKK13570.1 - 0.0037 17.5 0.1 0.011 15.9 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KKK13570.1 - 0.0088 15.3 0.2 0.025 13.8 0.1 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KKK13570.1 - 0.0091 15.1 0.0 0.014 14.5 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_4 PF01565.23 KKK13570.1 - 1.6 8.5 3.9 13 5.5 0.4 3.3 3 0 0 3 3 3 0 FAD binding domain RCC1 PF00415.18 KKK13571.1 - 1.8e-21 76.5 10.8 1.4e-05 25.6 0.2 7.4 7 1 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KKK13571.1 - 1.9e-13 49.8 13.8 1.2e-09 37.7 0.0 5.6 6 0 0 6 6 6 2 Regulator of chromosome condensation (RCC1) repeat SUKH-3 PF14433.6 KKK13571.1 - 0.021 15.3 0.0 2.5 8.6 0.0 3.2 3 0 0 3 3 3 0 SUKH-3 immunity protein PUF PF00806.19 KKK13572.1 - 2.5e-16 58.3 0.0 0.034 13.8 0.0 7.7 8 0 0 8 8 8 5 Pumilio-family RNA binding repeat Pkinase PF00069.25 KKK13573.1 - 5.4e-65 219.4 0.0 7.9e-65 218.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK13573.1 - 9.1e-44 149.7 0.0 1.3e-43 149.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KKK13573.1 - 2.2e-09 37.0 0.0 6.7e-07 28.9 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 KKK13573.1 - 0.0014 17.5 0.0 0.0026 16.6 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KKK13573.1 - 0.014 14.7 0.0 0.024 14.0 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KKK13573.1 - 0.11 12.3 0.0 0.27 11.1 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Sec34 PF04136.15 KKK13574.1 - 2.2e-49 167.2 1.5 4.1e-49 166.3 1.5 1.5 1 0 0 1 1 1 1 Sec34-like family Exo70 PF03081.15 KKK13574.1 - 0.013 14.5 1.5 0.1 11.6 0.0 2.5 3 0 0 3 3 3 0 Exo70 exocyst complex subunit NPV_P10 PF05531.12 KKK13574.1 - 0.092 13.2 0.1 5.4 7.6 0.0 2.9 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Metallopep PF12044.8 KKK13575.1 - 9.6e-173 574.7 0.0 1.3e-172 574.3 0.0 1.2 1 0 0 1 1 1 1 Putative peptidase family Jacalin PF01419.17 KKK13575.1 - 0.0055 16.6 0.0 0.034 14.1 0.0 2.1 1 1 1 2 2 2 1 Jacalin-like lectin domain Reprolysin_5 PF13688.6 KKK13575.1 - 0.037 14.2 0.5 0.08 13.1 0.5 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12 NACHT PF05729.12 KKK13576.1 - 2.9e-06 27.3 0.0 7.1e-06 26.0 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KKK13576.1 - 0.0047 17.3 0.0 0.014 15.8 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain Cas9-BH PF16593.5 KKK13576.1 - 0.033 13.9 0.2 0.085 12.6 0.2 1.7 1 0 0 1 1 1 0 Bridge helix of CRISPR-associated endonuclease Cas9 AAA_22 PF13401.6 KKK13576.1 - 0.06 13.6 0.6 0.19 12.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain DNA_ligase_A_M PF01068.21 KKK13577.1 - 1.1e-53 182.0 0.1 9e-51 172.4 0.0 2.3 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 KKK13577.1 - 3.3e-36 125.2 0.0 7.8e-36 124.0 0.0 1.7 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 KKK13577.1 - 4.8e-19 68.8 0.0 2.1e-18 66.7 0.0 2.2 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 KKK13577.1 - 0.0053 17.1 0.0 0.012 15.9 0.0 1.6 1 0 0 1 1 1 1 RNA ligase Rotamase_2 PF13145.6 KKK13577.1 - 0.13 13.1 5.2 2.3 9.0 1.4 3.3 3 0 0 3 3 3 0 PPIC-type PPIASE domain Whi5 PF08528.11 KKK13578.1 - 0.00082 18.9 0.4 0.0015 18.1 0.4 1.4 1 0 0 1 1 1 1 Whi5 like AAA PF00004.29 KKK13579.1 - 1.3e-18 67.7 0.0 2.2e-18 67.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KKK13579.1 - 0.0025 18.1 0.3 0.012 15.9 0.3 2.1 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KKK13579.1 - 0.056 13.8 0.0 0.14 12.5 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain Zeta_toxin PF06414.12 KKK13579.1 - 0.067 12.5 0.0 0.23 10.7 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin AAA_5 PF07728.14 KKK13579.1 - 0.12 12.4 0.0 0.29 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RINT1_TIP1 PF04437.13 KKK13580.1 - 3.4e-182 606.8 0.0 8e-182 605.6 0.0 1.6 2 0 0 2 2 2 1 RINT-1 / TIP-1 family CRISPR_Cse2 PF09485.10 KKK13580.1 - 0.0071 16.9 4.8 0.013 16.0 3.7 2.0 2 0 0 2 2 2 1 CRISPR-associated protein Cse2 (CRISPR_cse2) GCN5L1 PF06320.13 KKK13580.1 - 0.2 11.8 4.2 4.9 7.3 4.9 2.6 2 0 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) Val_tRNA-synt_C PF10458.9 KKK13580.1 - 0.32 11.3 3.7 1.2 9.5 3.7 2.1 1 0 0 1 1 1 0 Valyl tRNA synthetase tRNA binding arm TBCC_N PF16752.5 KKK13580.1 - 0.36 11.3 8.8 1.4 9.4 8.8 2.1 1 0 0 1 1 1 0 Tubulin-specific chaperone C N-terminal domain Exonuc_VII_L PF02601.15 KKK13580.1 - 0.41 10.2 8.0 0.55 9.7 6.5 1.9 2 0 0 2 2 2 0 Exonuclease VII, large subunit ANAPC_CDC26 PF10471.9 KKK13580.1 - 1.2 10.0 6.1 3.3 8.6 6.1 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit CDC26 Fib_alpha PF08702.10 KKK13580.1 - 1.3 9.2 3.3 3.8 7.7 2.6 2.2 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Spc24 PF08286.11 KKK13580.1 - 2.7 8.3 6.4 7.8 6.8 6.1 1.9 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 OmpH PF03938.14 KKK13580.1 - 3.2 8.1 8.3 10 6.5 8.3 1.9 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) TPR_16 PF13432.6 KKK13580.1 - 3.3 8.4 9.0 1.9 9.2 4.6 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat FUSC PF04632.12 KKK13580.1 - 7.4 5.0 8.1 13 4.1 8.1 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family Pyridoxal_deC PF00282.19 KKK13581.1 - 1.7e-77 260.7 0.0 5.9e-77 258.9 0.0 1.9 2 1 0 2 2 2 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 KKK13581.1 - 2.4e-08 33.3 0.0 3.9e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KKK13581.1 - 1.9e-05 24.1 0.0 2.4e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase HTH_1 PF00126.27 KKK13581.1 - 0.091 12.7 0.0 0.25 11.3 0.0 1.8 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family SepSecS PF05889.13 KKK13581.1 - 0.15 10.7 0.0 0.27 9.9 0.0 1.4 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Nuc_sug_transp PF04142.15 KKK13582.1 - 1.7e-79 267.2 7.2 2.7e-79 266.6 7.2 1.3 1 0 0 1 1 1 1 Nucleotide-sugar transporter Sec63 PF02889.16 KKK13582.1 - 1.7e-31 109.4 0.0 2.5e-31 108.8 0.0 1.2 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.29 KKK13582.1 - 4.9e-26 91.6 0.1 9.6e-26 90.6 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KKK13582.1 - 3.3e-15 56.5 0.0 6.1e-15 55.6 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KKK13582.1 - 6.2e-08 33.0 0.0 6.8e-06 26.4 0.0 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 KKK13582.1 - 2.5e-05 24.6 0.2 9e-05 22.8 0.2 1.9 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KKK13582.1 - 0.0015 18.3 0.0 0.0027 17.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KKK13582.1 - 0.0017 18.7 0.0 0.0049 17.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain EamA PF00892.20 KKK13582.1 - 0.002 18.3 29.2 0.0022 18.2 8.2 2.4 2 0 0 2 2 2 1 EamA-like transporter family Helicase_RecD PF05127.14 KKK13582.1 - 0.043 13.7 0.0 0.1 12.4 0.0 1.7 1 0 0 1 1 1 0 Helicase AAA_7 PF12775.7 KKK13582.1 - 0.081 12.4 0.0 2.7 7.5 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region T2SSE PF00437.20 KKK13582.1 - 0.09 11.8 0.0 0.19 10.8 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein Ost5 PF05251.12 KKK13582.1 - 0.16 12.3 2.7 0.44 10.8 1.0 2.7 2 0 0 2 2 1 0 Oligosaccharyltransferase subunit 5 UvrD-helicase PF00580.21 KKK13582.1 - 0.16 11.5 0.0 0.29 10.6 0.0 1.4 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain TMEM234 PF10639.9 KKK13582.1 - 0.75 9.9 4.0 1.1 9.4 0.4 2.5 2 0 0 2 2 2 0 Putative transmembrane family 234 LRR_6 PF13516.6 KKK13583.1 - 1.3e-07 31.1 0.7 0.0074 16.3 0.0 4.2 4 0 0 4 4 4 2 Leucine Rich repeat LRR_4 PF12799.7 KKK13583.1 - 3.7e-06 27.2 0.8 0.0014 19.0 0.1 2.9 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KKK13583.1 - 0.00015 21.4 1.9 2.1 8.2 0.0 4.1 3 1 1 4 4 4 2 Leucine rich repeat LRR_1 PF00560.33 KKK13583.1 - 0.0014 18.8 0.1 5.7 7.9 0.0 3.4 3 0 0 3 3 3 2 Leucine Rich Repeat HORMA PF02301.18 KKK13584.1 - 2.9e-62 210.0 0.0 4.8e-62 209.3 0.0 1.3 1 0 0 1 1 1 1 HORMA domain PHD PF00628.29 KKK13584.1 - 0.0055 16.6 7.1 0.011 15.6 7.1 1.5 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 KKK13584.1 - 0.13 11.8 3.1 0.31 10.6 3.1 1.7 1 0 0 1 1 1 0 PHD-finger MMR_HSR1 PF01926.23 KKK13586.1 - 1.6e-18 66.9 0.0 2.4e-18 66.3 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 KKK13586.1 - 1.1e-05 25.5 0.0 0.00019 21.5 0.0 2.2 1 1 1 2 2 2 1 Dynamin family RsgA_GTPase PF03193.16 KKK13586.1 - 0.00023 21.1 0.2 0.0054 16.7 0.1 2.2 2 0 0 2 2 2 1 RsgA GTPase FeoB_N PF02421.18 KKK13586.1 - 0.00069 19.2 0.0 0.001 18.6 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 KKK13586.1 - 0.0017 17.9 0.0 0.0081 15.7 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AIG1 PF04548.16 KKK13586.1 - 0.008 15.5 0.0 0.013 14.9 0.0 1.3 1 0 0 1 1 1 1 AIG1 family ABC_tran PF00005.27 KKK13586.1 - 0.027 15.0 0.1 0.044 14.3 0.1 1.5 1 1 0 1 1 1 0 ABC transporter SRPRB PF09439.10 KKK13586.1 - 0.045 13.2 0.0 0.061 12.7 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_29 PF13555.6 KKK13586.1 - 0.081 12.7 0.0 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Roc PF08477.13 KKK13586.1 - 0.13 12.5 0.0 0.28 11.4 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase WD40 PF00400.32 KKK13587.1 - 3.4e-40 135.3 19.6 1.7e-06 28.6 0.3 7.9 7 0 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.7 KKK13587.1 - 3.3e-08 33.3 0.1 6.7e-08 32.3 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KKK13587.1 - 1.9e-07 30.8 0.1 5.2e-07 29.4 0.1 1.8 1 0 0 1 1 1 1 F-box domain ANAPC4_WD40 PF12894.7 KKK13587.1 - 3.6e-06 27.2 1.1 3.7 7.9 0.0 5.2 2 2 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KKK13587.1 - 0.0082 14.8 7.1 5.4 5.5 0.1 5.0 6 1 1 7 7 7 2 Nucleoporin Nup120/160 F-box_4 PF15966.5 KKK13587.1 - 0.036 14.0 0.0 0.091 12.6 0.0 1.7 1 0 0 1 1 1 0 F-box Clat_adaptor_s PF01217.20 KKK13588.1 - 3.1e-42 143.9 1.1 9.4e-42 142.3 0.0 2.3 3 1 0 3 3 3 1 Clathrin adaptor complex small chain Ribosomal_L7Ae PF01248.26 KKK13588.1 - 4.6e-23 80.8 1.0 8.1e-23 80.0 1.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family CLPTM1 PF05602.12 KKK13588.1 - 0.13 11.2 0.2 0.22 10.5 0.2 1.3 1 0 0 1 1 1 0 Cleft lip and palate transmembrane protein 1 (CLPTM1) Med13_C PF06333.12 KKK13598.1 - 1.6e-91 307.0 0.5 1.6e-91 307.0 0.5 1.9 2 0 0 2 2 2 1 Mediator complex subunit 13 C-terminal domain Med13_N PF11597.8 KKK13598.1 - 9.7e-72 242.0 0.6 1.5e-71 241.4 0.6 1.3 1 0 0 1 1 1 1 Mediator complex subunit 13 N-terminal MID_MedPIWI PF18296.1 KKK13598.1 - 4.5e-35 121.6 0.5 1.1e-19 71.2 0.4 2.5 1 1 1 2 2 2 2 MID domain of medPIWI NUC153 PF08159.12 KKK13599.1 - 4.8e-12 45.5 0.5 1.2e-11 44.2 0.5 1.7 1 0 0 1 1 1 1 NUC153 domain WD40 PF00400.32 KKK13599.1 - 1.6e-05 25.6 0.0 0.7 10.9 0.0 4.9 5 0 0 5 5 5 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKK13599.1 - 0.021 15.1 0.0 0.092 13.1 0.0 2.1 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain SAPS PF04499.15 KKK13599.1 - 3.6 6.2 6.7 5.3 5.7 6.7 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein GREB1 PF15782.5 KKK13599.1 - 6.1 3.8 7.7 8.4 3.4 7.7 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer RCC1 PF00415.18 KKK13600.1 - 2.2e-22 79.4 0.4 6.9e-05 23.4 0.0 6.1 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.31 KKK13600.1 - 5.3e-15 55.6 0.3 4.4e-09 36.5 0.0 2.7 2 0 0 2 2 2 2 BTB/POZ domain RCC1_2 PF13540.6 KKK13600.1 - 5.5e-13 48.3 6.3 3.8e-09 36.1 0.2 4.2 4 0 0 4 4 4 2 Regulator of chromosome condensation (RCC1) repeat Ank_4 PF13637.6 KKK13600.1 - 2.8e-06 27.8 0.2 6e-05 23.5 0.1 2.6 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KKK13600.1 - 3.7e-05 23.8 0.1 0.48 11.2 0.0 3.3 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 KKK13600.1 - 0.0026 18.3 0.1 0.006 17.2 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KKK13600.1 - 0.084 13.2 0.1 1.4 9.3 0.0 2.9 3 0 0 3 3 3 0 Ankyrin repeats (many copies) FAD_binding_6 PF00970.24 KKK13601.1 - 9.9e-33 112.5 0.0 1.5e-32 111.9 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 KKK13601.1 - 8.1e-29 100.5 0.0 1.3e-28 99.8 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 KKK13601.1 - 1.4e-06 28.5 0.0 0.0002 21.5 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 KKK13601.1 - 0.012 15.8 0.0 0.022 15.0 0.0 1.4 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain DUF4176 PF13780.6 KKK13601.1 - 0.11 12.6 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4176) DUF3605 PF12239.8 KKK13602.1 - 2.9e-57 193.3 0.0 3.4e-57 193.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) SMC_N PF02463.19 KKK13603.1 - 6.5e-73 244.8 0.0 1.1e-72 244.0 0.0 1.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KKK13603.1 - 6e-32 110.4 0.1 3.2e-31 108.1 0.0 2.4 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.6 KKK13603.1 - 4.3e-19 69.8 0.2 4.3e-19 69.8 0.2 7.4 1 1 3 5 5 2 1 AAA domain AAA_21 PF13304.6 KKK13603.1 - 3.7e-16 59.8 13.5 2.2e-10 40.8 0.0 4.1 4 1 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 KKK13603.1 - 2.3e-13 50.6 55.5 2.8e-07 30.6 24.6 4.7 2 2 1 3 3 2 2 AAA ATPase domain APG6_N PF17675.1 KKK13603.1 - 0.00073 20.1 9.6 0.00073 20.1 9.6 8.5 3 2 5 8 8 8 4 Apg6 coiled-coil region Spc7 PF08317.11 KKK13603.1 - 0.0045 15.9 9.6 0.0045 15.9 9.6 7.5 2 2 5 7 7 7 2 Spc7 kinetochore protein AAA_29 PF13555.6 KKK13603.1 - 0.0051 16.5 0.0 0.012 15.3 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain FliD_N PF02465.18 KKK13603.1 - 0.026 15.2 1.3 0.026 15.2 1.3 8.4 5 3 3 8 8 8 0 Flagellar hook-associated protein 2 N-terminus DUF1192 PF06698.11 KKK13603.1 - 0.079 13.0 0.1 0.079 13.0 0.1 5.8 7 0 0 7 7 6 0 Protein of unknown function (DUF1192) FtsK_SpoIIIE PF01580.18 KKK13603.1 - 0.14 11.5 0.0 0.14 11.5 0.0 3.9 3 1 1 4 4 4 0 FtsK/SpoIIIE family ABC_tran PF00005.27 KKK13603.1 - 0.51 10.8 0.0 0.51 10.8 0.0 6.1 3 2 0 3 3 1 0 ABC transporter DUF87 PF01935.17 KKK13603.1 - 2.9 7.9 0.0 2.9 7.9 0.0 6.7 3 2 1 6 6 5 0 Helicase HerA, central domain RIO1 PF01163.22 KKK13604.1 - 5.5e-74 247.9 0.1 5.5e-74 247.9 0.1 1.8 2 0 0 2 2 2 1 RIO1 family APH PF01636.23 KKK13604.1 - 0.061 13.2 0.0 12 5.7 0.0 2.5 1 1 1 2 2 2 0 Phosphotransferase enzyme family ABC_tran PF00005.27 KKK13605.1 - 3.1e-26 92.5 0.5 4.6e-26 92.0 0.1 1.5 2 0 0 2 2 1 1 ABC transporter RsgA_GTPase PF03193.16 KKK13605.1 - 7.5e-07 29.2 0.2 9e-05 22.4 0.0 2.9 3 0 0 3 3 3 1 RsgA GTPase AAA_16 PF13191.6 KKK13605.1 - 3.4e-06 27.6 0.4 5.3e-06 26.9 0.1 1.7 2 1 0 2 2 1 1 AAA ATPase domain AAA_21 PF13304.6 KKK13605.1 - 9.6e-06 25.6 1.0 0.1 12.4 0.0 3.1 3 1 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 KKK13605.1 - 9.7e-06 25.3 0.0 1.8e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 KKK13605.1 - 0.00015 22.2 0.1 0.001 19.5 0.1 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) SMC_N PF02463.19 KKK13605.1 - 0.00015 21.2 0.0 0.00037 20.0 0.0 1.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain Rad17 PF03215.15 KKK13605.1 - 0.00049 20.1 0.0 0.0014 18.6 0.0 1.8 2 0 0 2 2 2 1 Rad17 P-loop domain NACHT PF05729.12 KKK13605.1 - 0.002 18.0 0.0 0.0049 16.8 0.0 1.6 1 0 0 1 1 1 1 NACHT domain IstB_IS21 PF01695.17 KKK13605.1 - 0.0022 17.8 0.1 0.01 15.5 0.0 2.1 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_18 PF13238.6 KKK13605.1 - 0.0036 17.8 0.1 0.0085 16.6 0.1 1.7 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 KKK13605.1 - 0.0044 17.4 0.0 0.017 15.5 0.0 2.0 2 0 0 2 2 1 1 RNA helicase AAA_22 PF13401.6 KKK13605.1 - 0.0044 17.3 0.1 0.01 16.1 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 KKK13605.1 - 0.0045 17.2 0.4 0.0094 16.2 0.4 1.5 1 0 0 1 1 1 1 AAA domain AAA_13 PF13166.6 KKK13605.1 - 0.0046 15.7 1.0 0.01 14.5 0.1 1.8 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 KKK13605.1 - 0.0047 17.0 0.0 0.015 15.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 KKK13605.1 - 0.0049 16.8 0.0 0.0084 16.1 0.0 1.4 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea MMR_HSR1 PF01926.23 KKK13605.1 - 0.0081 16.2 0.1 0.018 15.1 0.1 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase RuvB_N PF05496.12 KKK13605.1 - 0.013 15.2 0.0 0.027 14.2 0.0 1.6 1 1 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_30 PF13604.6 KKK13605.1 - 0.014 15.2 0.7 0.026 14.2 0.1 1.7 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 KKK13605.1 - 0.015 15.2 0.1 0.062 13.2 0.0 2.0 2 0 0 2 2 2 0 NTPase T2SSE PF00437.20 KKK13605.1 - 0.039 13.0 0.1 0.069 12.2 0.1 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_33 PF13671.6 KKK13605.1 - 0.039 14.1 0.0 0.074 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 KKK13605.1 - 0.042 13.6 0.2 0.19 11.4 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ATP-synt_ab PF00006.25 KKK13605.1 - 0.052 13.2 0.0 0.096 12.3 0.0 1.5 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_35 PF14516.6 KKK13605.1 - 0.055 12.3 0.0 0.09 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain AAA_29 PF13555.6 KKK13605.1 - 0.058 13.2 0.0 0.16 11.8 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain TsaE PF02367.17 KKK13605.1 - 0.063 13.3 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_5 PF07728.14 KKK13605.1 - 0.083 12.9 0.1 0.25 11.4 0.1 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_23 PF13476.6 KKK13605.1 - 0.11 13.0 1.2 0.19 12.2 0.2 1.9 2 1 0 2 2 1 0 AAA domain SRP54 PF00448.22 KKK13605.1 - 0.13 11.9 0.1 0.3 10.7 0.1 1.6 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_7 PF12775.7 KKK13605.1 - 0.14 11.7 0.1 0.36 10.3 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region MobB PF03205.14 KKK13605.1 - 0.14 12.0 0.0 0.32 10.9 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B tRNA-synt_1d PF00750.19 KKK13606.1 - 1.8e-99 333.0 3.9 4.4e-98 328.4 3.9 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 KKK13606.1 - 1.1e-27 96.6 1.7 1.4e-27 96.3 0.0 2.1 2 0 0 2 2 2 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.16 KKK13606.1 - 2.1e-05 25.0 0.3 0.00012 22.6 0.0 2.4 2 0 0 2 2 2 1 Arginyl tRNA synthetase N terminal domain FlgN PF05130.12 KKK13606.1 - 0.099 13.2 0.9 0.31 11.5 0.9 1.8 1 0 0 1 1 1 0 FlgN protein DivIVA PF05103.13 KKK13606.1 - 0.16 12.1 3.9 8.5 6.5 0.1 2.7 2 0 0 2 2 2 0 DivIVA protein FliD_N PF02465.18 KKK13606.1 - 0.41 11.4 2.1 1.9 9.3 2.1 2.1 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus CENP-C_C PF11699.8 KKK13613.1 - 4.2e-36 123.0 0.4 4.2e-36 123.0 0.4 1.6 2 0 0 2 2 2 1 Mif2/CENP-C like Mif2_N PF15624.6 KKK13613.1 - 7e-34 117.4 4.0 7e-34 117.4 4.0 3.6 2 1 0 3 3 3 1 Kinetochore CENP-C fungal homologue, Mif2, N-terminal Cupin_2 PF07883.11 KKK13613.1 - 1e-07 31.6 0.0 3.1e-07 30.0 0.0 1.8 2 0 0 2 2 2 1 Cupin domain Cupin_1 PF00190.22 KKK13613.1 - 0.098 12.3 0.1 0.2 11.3 0.1 1.4 1 0 0 1 1 1 0 Cupin F-box PF00646.33 KKK13614.1 - 1.2e-08 34.6 1.4 2.5e-08 33.6 1.4 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KKK13614.1 - 2.1e-08 33.9 0.4 4.7e-08 32.8 0.4 1.6 1 0 0 1 1 1 1 F-box-like WD40 PF00400.32 KKK13614.1 - 0.023 15.6 1.2 9 7.4 0.5 4.0 3 0 0 3 3 3 0 WD domain, G-beta repeat SAE2 PF08573.10 KKK13615.1 - 1.9e-34 119.1 0.0 1.9e-34 119.1 0.0 3.4 3 1 0 3 3 3 1 DNA repair protein endonuclease SAE2/CtIP C-terminus SH3BP5 PF05276.14 KKK13615.1 - 0.0022 17.9 7.4 0.0044 16.8 7.4 1.6 1 1 0 1 1 1 1 SH3 domain-binding protein 5 (SH3BP5) DUF4200 PF13863.6 KKK13615.1 - 0.0099 16.3 6.7 0.0099 16.3 6.7 2.5 3 0 0 3 3 3 1 Domain of unknown function (DUF4200) DUF1664 PF07889.12 KKK13615.1 - 1.7 8.7 3.7 1.6 8.8 1.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Bcr-Abl_Oligo PF09036.10 KKK13615.1 - 2 8.5 5.9 9 6.4 0.1 3.0 3 0 0 3 3 3 0 Bcr-Abl oncoprotein oligomerisation domain FUSC PF04632.12 KKK13615.1 - 2.3 6.6 3.7 4.4 5.7 3.7 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family GldM_N PF12081.8 KKK13615.1 - 2.3 8.3 5.6 4.2 7.4 2.4 2.2 2 0 0 2 2 2 0 GldM N-terminal domain AAA_13 PF13166.6 KKK13615.1 - 3.2 6.3 9.8 1.6 7.2 5.9 2.0 1 1 1 2 2 2 0 AAA domain KLRAQ PF10205.9 KKK13615.1 - 4.3 7.6 8.3 15 5.9 0.7 2.8 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein XhlA PF10779.9 KKK13615.1 - 5.1 7.4 5.2 1.6 9.0 1.1 2.3 2 0 0 2 2 2 0 Haemolysin XhlA Pex16 PF08610.10 KKK13616.1 - 9.8e-140 465.3 0.0 1.1e-139 465.1 0.0 1.0 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) RNase_HII PF01351.18 KKK13617.1 - 1.7e-47 161.9 0.0 2.2e-47 161.5 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease HII Aldo_ket_red PF00248.21 KKK13619.1 - 7.4e-44 150.1 0.0 4.9e-42 144.1 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family UPF0061 PF02696.14 KKK13620.1 - 6.7e-130 434.0 0.0 8.5e-130 433.6 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family TOBE PF03459.17 KKK13620.1 - 0.12 12.7 0.0 0.29 11.5 0.0 1.5 1 0 0 1 1 1 0 TOBE domain zf-CCHC PF00098.23 KKK13621.1 - 3.7e-52 172.2 62.5 2.2e-09 37.0 2.0 7.3 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.6 KKK13621.1 - 2.3e-15 56.0 44.3 0.0053 16.5 0.7 7.1 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_3 PF13917.6 KKK13621.1 - 7.1e-06 25.9 46.8 0.013 15.5 0.5 6.6 3 2 4 7 7 7 6 Zinc knuckle zf-CCHC_5 PF14787.6 KKK13621.1 - 0.00056 19.6 44.7 0.24 11.2 1.2 7.1 6 1 1 7 7 7 7 GAG-polyprotein viral zinc-finger zf-CCHC_6 PF15288.6 KKK13621.1 - 0.0021 17.9 59.6 0.031 14.1 0.7 7.7 6 2 2 8 8 8 5 Zinc knuckle Adeno_E3_CR2 PF02439.15 KKK13633.1 - 0.33 10.7 1.0 0.59 9.9 1.0 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF1992 PF09350.10 KKK13634.1 - 1.7e-21 76.1 1.5 2.9e-21 75.4 0.3 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1992) TAFII28 PF04719.14 KKK13635.1 - 9.7e-26 89.7 0.3 2.8e-25 88.2 0.3 1.7 1 1 0 1 1 1 1 hTAFII28-like protein conserved region FAM86 PF14904.6 KKK13635.1 - 0.11 12.6 0.0 0.17 12.0 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function Mid2 PF04478.12 KKK13637.1 - 0.0027 17.6 0.0 0.0075 16.1 0.0 1.8 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor Phage_fiber PF03335.13 KKK13637.1 - 0.074 13.2 1.0 0.23 11.7 1.0 1.9 1 0 0 1 1 1 0 Phage tail fibre repeat FAD_binding_4 PF01565.23 KKK13638.1 - 5e-24 84.6 0.2 7.9e-24 84.0 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KKK13638.1 - 0.00084 19.4 0.0 0.0018 18.3 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like Pro_isomerase PF00160.21 KKK13640.1 - 4.2e-46 157.1 1.7 2.3e-44 151.5 1.7 2.0 1 1 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD CBM_4_9 PF02018.17 KKK13641.1 - 4e-11 43.3 0.1 4.8e-11 43.1 0.1 1.0 1 0 0 1 1 1 1 Carbohydrate binding domain Sugar_tr PF00083.24 KKK13642.1 - 7e-39 133.9 33.9 6.4e-25 87.9 12.0 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KKK13642.1 - 9.4e-24 84.0 40.9 5e-12 45.4 19.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily PhyH PF05721.13 KKK13643.1 - 1.7e-27 97.1 0.0 2.7e-27 96.4 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) HD PF01966.22 KKK13643.1 - 9.2e-07 29.1 0.0 2.4e-06 27.8 0.0 1.7 1 0 0 1 1 1 1 HD domain 2OG-FeII_Oxy_3 PF13640.6 KKK13643.1 - 0.0069 17.3 0.0 0.017 16.0 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MIOX PF05153.15 KKK13643.1 - 0.011 15.3 0.0 0.022 14.3 0.0 1.4 1 0 0 1 1 1 0 Myo-inositol oxygenase 2OG-FeII_Oxy_5 PF13759.6 KKK13643.1 - 0.051 14.0 0.0 0.13 12.7 0.0 1.7 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase HDOD PF08668.12 KKK13643.1 - 0.11 12.0 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 HDOD domain Cellulase PF00150.18 KKK13644.1 - 1.7e-10 40.8 1.0 6.1e-06 25.9 0.0 2.5 2 1 1 3 3 3 2 Cellulase (glycosyl hydrolase family 5) APH PF01636.23 KKK13651.1 - 0.013 15.5 0.1 0.75 9.7 0.1 2.2 1 1 0 1 1 1 0 Phosphotransferase enzyme family DUF4381 PF14316.6 KKK13653.1 - 0.068 13.4 0.4 0.13 12.5 0.2 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) NAM-associated PF14303.6 KKK13653.1 - 1.3 9.8 6.6 11 6.7 0.0 2.2 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain Ctr PF04145.15 KKK13653.1 - 1.9 9.1 0.0 1.9 9.1 0.0 2.3 2 1 1 3 3 3 0 Ctr copper transporter family Piwi PF02171.17 KKK13654.1 - 4.6e-73 246.1 0.0 8.9e-73 245.1 0.0 1.5 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 KKK13654.1 - 9.6e-19 68.4 0.0 1.8e-18 67.5 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL1 PF08699.10 KKK13654.1 - 3.5e-14 52.2 0.2 8.2e-14 51.0 0.2 1.7 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoL2 PF16488.5 KKK13654.1 - 3.6e-11 43.2 0.0 1.2e-10 41.6 0.0 2.0 1 0 0 1 1 1 1 Argonaute linker 2 domain PAZ PF02170.22 KKK13654.1 - 1.5e-09 37.8 0.0 4.5e-09 36.2 0.0 1.8 1 1 0 1 1 1 1 PAZ domain ArgoMid PF16487.5 KKK13654.1 - 0.0012 19.0 0.0 0.0036 17.5 0.0 1.7 1 0 0 1 1 1 1 Mid domain of argonaute MFS_1 PF07690.16 KKK13655.1 - 4.3e-33 114.7 25.5 4.3e-33 114.7 25.5 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Phosducin PF02114.16 KKK13656.1 - 3.4e-06 26.2 0.0 3.8e-06 26.0 0.0 1.1 1 0 0 1 1 1 1 Phosducin DLIC PF05783.11 KKK13661.1 - 3.7e-37 128.3 2.1 3.2e-33 115.3 0.0 3.4 2 2 0 2 2 2 2 Dynein light intermediate chain (DLIC) Urb2 PF10441.9 KKK13661.1 - 0.11 12.4 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Urb2/Npa2 family RRM_1 PF00076.22 KKK13662.1 - 4.4e-19 68.1 0.0 1e-18 66.9 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KKK13662.1 - 1.2e-05 25.3 0.0 2.9e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif RsbU_N PF08673.10 KKK13662.1 - 0.074 13.1 0.4 1.2 9.3 0.3 2.3 2 0 0 2 2 2 0 Phosphoserine phosphatase RsbU, N-terminal domain RRM_3 PF08777.11 KKK13662.1 - 0.076 13.1 2.4 0.14 12.2 0.0 2.4 1 1 1 2 2 2 0 RNA binding motif WD40 PF00400.32 KKK13663.1 - 2e-05 25.2 0.0 0.29 12.1 0.0 3.2 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKK13663.1 - 0.0013 18.9 0.0 0.32 11.3 0.0 3.3 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain IKI3 PF04762.12 KKK13663.1 - 0.0063 14.6 0.0 0.0084 14.2 0.0 1.1 1 0 0 1 1 1 1 IKI3 family Ge1_WD40 PF16529.5 KKK13663.1 - 0.058 12.3 0.0 0.1 11.5 0.0 1.4 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Frtz PF11768.8 KKK13663.1 - 0.23 9.7 0.0 0.38 9.0 0.0 1.2 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz EMP70 PF02990.16 KKK13679.1 - 3.9e-195 649.4 0.0 5.1e-195 649.1 0.0 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 ubiquitin PF00240.23 KKK13680.1 - 9.9e-21 73.3 0.0 1.5e-20 72.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.31 KKK13680.1 - 1.3e-08 34.6 0.3 3.1e-08 33.4 0.3 1.7 1 0 0 1 1 1 1 UBA/TS-N domain Rad60-SLD PF11976.8 KKK13680.1 - 2.6e-07 30.4 0.0 4.4e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 KKK13680.1 - 5.1e-05 23.8 0.0 0.00012 22.6 0.0 1.5 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.6 KKK13680.1 - 6.9e-05 22.9 0.0 0.00012 22.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like YukD PF08817.10 KKK13680.1 - 0.00029 21.5 0.0 0.00069 20.3 0.0 1.7 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukD Ubiquitin_2 PF14560.6 KKK13680.1 - 0.24 11.9 0.0 0.53 10.8 0.0 1.6 1 1 0 1 1 1 0 Ubiquitin-like domain GerD PF17898.1 KKK13680.1 - 0.53 10.2 6.6 0.27 11.2 4.0 1.8 2 1 0 2 2 2 0 Spore germination GerD central core domain STI1 PF17830.1 KKK13680.1 - 2.6 8.0 22.0 1.9 8.5 2.4 3.5 2 1 1 3 3 3 0 STI1 domain BP28CT PF08146.12 KKK13681.1 - 2.4e-41 141.2 0.3 9.1e-41 139.3 0.3 2.1 1 0 0 1 1 1 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.8 KKK13681.1 - 1.4e-31 109.2 4.2 3.2e-28 98.4 0.8 4.6 3 0 0 3 3 3 2 U3 small nucleolar RNA-associated protein 10 HEAT_2 PF13646.6 KKK13681.1 - 2e-06 28.1 7.7 0.42 11.0 0.2 6.1 5 2 1 6 6 6 4 HEAT repeats HEAT PF02985.22 KKK13681.1 - 5.6e-06 26.2 2.0 0.09 13.1 0.0 5.8 5 0 0 5 5 5 1 HEAT repeat Arm PF00514.23 KKK13681.1 - 0.06 13.4 4.3 30 4.9 0.0 4.8 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 KKK13681.1 - 2 9.0 16.0 8.2 7.1 0.4 7.2 9 0 0 9 9 9 0 HEAT-like repeat NRDE-2 PF08424.10 KKK13682.1 - 3.1e-95 319.0 4.9 2e-94 316.4 3.4 2.3 2 0 0 2 2 2 1 NRDE-2, necessary for RNA interference TPR_16 PF13432.6 KKK13682.1 - 0.071 13.8 0.7 1.4 9.6 0.1 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 KKK13682.1 - 0.36 11.8 3.5 27 5.9 0.0 4.6 7 0 0 7 7 7 0 Tetratricopeptide repeat MMS1_N PF10433.9 KKK13683.1 - 8.6e-157 522.7 0.0 1.2e-156 522.2 0.0 1.2 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 KKK13683.1 - 3e-101 339.0 0.0 1.5e-100 336.7 0.0 2.1 2 0 0 2 2 2 1 CPSF A subunit region ANAPC4_WD40 PF12894.7 KKK13683.1 - 0.031 14.6 0.0 0.45 10.8 0.0 2.9 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Bul1_N PF04425.12 KKK13684.1 - 2.5e-11 43.0 4.3 3.4e-07 29.4 1.4 2.3 1 1 1 2 2 2 2 Bul1 N terminus Arrestin_N PF00339.29 KKK13684.1 - 4.9e-06 26.7 0.0 1.2e-05 25.4 0.0 1.7 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Bul1_C PF04426.12 KKK13684.1 - 0.016 14.6 0.4 0.032 13.7 0.1 1.5 2 0 0 2 2 2 0 Bul1 C terminus Arrestin_C PF02752.22 KKK13684.1 - 0.11 13.0 0.1 3.1 8.2 0.0 2.4 2 0 0 2 2 2 0 Arrestin (or S-antigen), C-terminal domain NAD_binding_6 PF08030.12 KKK13685.1 - 2.3e-22 79.8 0.0 3.6e-22 79.1 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KKK13685.1 - 1.8e-21 76.3 0.0 3.9e-21 75.2 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 KKK13685.1 - 3.1e-20 72.5 12.9 3.1e-20 72.5 12.9 2.0 1 1 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.24 KKK13685.1 - 0.09 13.1 0.0 0.19 12.1 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain Sulfatase PF00884.23 KKK13687.1 - 4e-58 197.2 0.3 5.2e-58 196.9 0.3 1.1 1 0 0 1 1 1 1 Sulfatase Choline_sulf_C PF12411.8 KKK13687.1 - 3.9e-21 74.6 0.2 8.5e-21 73.5 0.2 1.6 1 0 0 1 1 1 1 Choline sulfatase enzyme C terminal Phosphodiest PF01663.22 KKK13687.1 - 1.2e-10 41.5 0.0 0.00017 21.3 0.0 2.4 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 KKK13687.1 - 0.0099 14.5 0.0 0.013 14.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Sulfatase_C PF14707.6 KKK13687.1 - 0.025 15.3 0.0 0.066 14.0 0.0 1.7 1 0 0 1 1 1 0 C-terminal region of aryl-sulfatase DUF1501 PF07394.12 KKK13687.1 - 0.041 12.9 0.0 0.068 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) Tim44 PF04280.15 KKK13688.1 - 2.1e-37 128.5 0.0 6e-37 127.0 0.0 1.7 2 0 0 2 2 2 1 Tim44-like domain DDRGK PF09756.9 KKK13688.1 - 2.3 7.8 10.2 0.64 9.6 3.6 2.2 2 0 0 2 2 2 0 DDRGK domain FAM176 PF14851.6 KKK13688.1 - 3.3 7.3 8.9 0.5 10.0 3.3 2.3 3 0 0 3 3 3 0 FAM176 family SGTA_dimer PF16546.5 KKK13689.1 - 2.7e-26 91.1 0.4 4.8e-26 90.3 0.4 1.4 1 0 0 1 1 1 1 Homodimerisation domain of SGTA TPR_1 PF00515.28 KKK13689.1 - 9.2e-13 47.4 6.8 0.00076 19.2 0.2 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KKK13689.1 - 5.2e-12 44.9 9.1 0.0042 17.1 0.8 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 KKK13689.1 - 3e-08 33.2 8.2 0.0018 18.3 0.1 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 KKK13689.1 - 3.9e-08 32.9 7.0 1.6e-06 27.7 2.9 2.9 2 1 1 3 3 3 2 TPR repeat TPR_7 PF13176.6 KKK13689.1 - 1.1e-05 25.1 0.7 1.8 8.8 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 KKK13689.1 - 4.1e-05 24.0 4.4 0.001 19.5 3.0 2.5 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 KKK13689.1 - 7.1e-05 22.9 1.6 0.022 15.1 0.5 3.2 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 KKK13689.1 - 0.00038 21.0 12.0 0.0039 17.8 7.8 2.9 2 1 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 KKK13689.1 - 0.00039 20.5 4.2 0.013 15.6 0.7 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 KKK13689.1 - 0.00044 20.5 7.8 0.015 15.5 3.8 2.8 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 KKK13689.1 - 0.0025 18.5 7.0 0.12 13.2 0.3 3.7 1 1 2 3 3 3 1 Tetratricopeptide repeat STI1 PF17830.1 KKK13689.1 - 0.0038 17.1 10.9 0.025 14.5 6.1 2.7 2 0 0 2 2 2 1 STI1 domain XPC-binding PF09280.11 KKK13689.1 - 0.005 16.6 5.2 0.019 14.7 5.2 2.0 1 1 0 1 1 1 1 XPC-binding domain GerD PF17898.1 KKK13689.1 - 0.12 12.3 2.9 1.4 8.9 1.2 2.8 2 1 0 2 2 2 0 Spore germination GerD central core domain TPR_10 PF13374.6 KKK13689.1 - 3 7.8 9.2 8.7 6.4 0.2 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 KKK13689.1 - 3.6 8.4 7.7 4.9 8.0 0.2 3.7 4 0 0 4 4 3 0 Tetratricopeptide repeat RIC1 PF07064.13 KKK13690.1 - 2.1e-83 279.6 0.0 3e-83 279.1 0.0 1.2 1 0 0 1 1 1 1 RIC1 Ank_5 PF13857.6 KKK13691.1 - 2.2e-17 62.9 0.0 1.9e-11 43.9 0.0 5.1 5 1 0 5 5 5 2 Ankyrin repeats (many copies) VPS9 PF02204.18 KKK13691.1 - 6e-16 58.6 0.0 1.3e-15 57.4 0.0 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Ank_2 PF12796.7 KKK13691.1 - 9.4e-14 51.8 0.0 0.00011 22.7 0.0 4.0 1 1 3 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KKK13691.1 - 3.4e-08 33.9 0.0 0.01 16.4 0.0 5.3 4 1 1 5 5 5 2 Ankyrin repeats (many copies) PX PF00787.24 KKK13691.1 - 4.3e-08 33.1 0.6 4.3e-08 33.1 0.6 1.9 2 0 0 2 2 2 1 PX domain Ank_3 PF13606.6 KKK13691.1 - 1.4e-05 25.0 0.1 7.7 7.4 0.0 5.9 5 0 0 5 5 5 1 Ankyrin repeat Ank PF00023.30 KKK13691.1 - 0.0011 19.3 0.1 6 7.5 0.0 4.3 5 0 0 5 5 5 1 Ankyrin repeat RasGEF PF00617.19 KKK13691.1 - 0.032 14.4 0.2 0.083 13.1 0.2 1.7 1 0 0 1 1 1 0 RasGEF domain Ribosomal_S11 PF00411.19 KKK13692.1 - 3.8e-06 27.3 0.0 2.2e-05 24.8 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein S11 MutS_I PF01624.20 KKK13722.1 - 9e-13 48.5 0.0 1.5e-12 47.8 0.0 1.3 1 0 0 1 1 1 1 MutS domain I Ndc1_Nup PF09531.10 KKK13722.1 - 5.5 5.6 4.3 5.3 5.6 4.3 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup RhoGAP PF00620.27 KKK13723.1 - 2.8e-30 105.2 0.0 4.6e-30 104.4 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain FXMR_C2 PF16098.5 KKK13723.1 - 0.015 15.7 2.0 0.015 15.7 2.0 2.2 2 0 0 2 2 2 0 Fragile X-related mental retardation protein C-terminal region 2 Prenyltrans PF00432.21 KKK13724.1 - 2.7e-51 171.0 10.3 6.9e-12 44.9 0.0 6.2 6 0 0 6 6 6 6 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 KKK13724.1 - 0.0005 19.3 0.0 0.18 10.8 0.0 3.2 3 1 0 3 3 3 2 Squalene-hopene cyclase N-terminal domain SQHop_cyclase_C PF13243.6 KKK13724.1 - 0.00085 18.5 0.0 0.1 11.6 0.0 2.6 1 1 1 2 2 2 2 Squalene-hopene cyclase C-terminal domain RRS1 PF04939.12 KKK13725.1 - 5e-58 195.5 1.9 6e-58 195.3 1.9 1.1 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) DUF1729 PF08354.10 KKK13726.1 - 1.8e-159 530.4 0.0 2.8e-159 529.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) Acyl_transf_1 PF00698.21 KKK13726.1 - 1.2e-90 304.3 0.0 2.1e-89 300.2 0.0 2.6 3 0 0 3 3 3 1 Acyl transferase domain FAS_meander PF17951.1 KKK13726.1 - 7.3e-52 175.1 0.0 1.9e-51 173.7 0.0 1.8 1 0 0 1 1 1 1 Fatty acid synthase meander beta sheet domain SAT PF16073.5 KKK13726.1 - 2.3e-40 138.8 0.0 1e-39 136.7 0.0 2.2 2 0 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis FAS_N PF17828.1 KKK13726.1 - 4.3e-39 133.5 0.0 3.4e-38 130.6 0.0 2.4 2 0 0 2 2 2 1 N-terminal domain in fatty acid synthase subunit beta MaoC_dehydratas PF01575.19 KKK13726.1 - 7.8e-39 132.0 0.0 2.2e-38 130.6 0.0 1.8 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 KKK13726.1 - 3.4e-22 79.0 0.0 1.1e-21 77.3 0.0 1.9 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase Kdo PF06293.14 KKK13727.1 - 4.4e-05 22.9 0.0 0.00014 21.3 0.0 1.7 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 KKK13727.1 - 0.0025 17.4 0.7 0.0075 15.9 0.0 1.9 2 0 0 2 2 2 1 Choline/ethanolamine kinase Pkinase PF00069.25 KKK13727.1 - 0.0026 17.2 0.0 0.0064 15.9 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KKK13727.1 - 0.0037 17.2 0.1 0.0037 17.2 0.1 3.2 2 1 1 3 3 3 1 Phosphotransferase enzyme family Peptidase_C6 PF00851.18 KKK13727.1 - 0.12 11.3 0.3 0.27 10.1 0.0 1.6 2 0 0 2 2 2 0 Helper component proteinase DUF2828 PF11443.8 KKK13727.1 - 0.15 10.1 2.6 0.23 9.5 2.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) DUF390 PF04094.14 KKK13727.1 - 0.58 8.4 8.1 0.9 7.8 8.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF390) RR_TM4-6 PF06459.12 KKK13727.1 - 1.3 8.8 6.6 3 7.6 6.6 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 ORC_WH_C PF18137.1 KKK13727.1 - 1.5 8.9 7.2 4.1 7.5 7.2 1.7 1 0 0 1 1 1 0 Origin recognition complex winged helix C-terminal Pox_MCEL PF03291.16 KKK13728.1 - 2.5e-64 217.5 0.0 1.2e-42 146.2 0.0 3.2 2 1 0 2 2 2 2 mRNA capping enzyme Methyltransf_25 PF13649.6 KKK13728.1 - 1.5e-07 32.0 0.0 0.014 16.1 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 KKK13728.1 - 3.9e-07 30.7 0.0 4.6e-06 27.3 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KKK13728.1 - 2.2e-05 25.0 0.0 0.052 14.2 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 KKK13728.1 - 0.00022 21.1 0.0 0.022 14.6 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KKK13728.1 - 0.00026 20.9 0.0 0.00064 19.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 KKK13728.1 - 0.022 14.0 0.0 0.035 13.3 0.0 1.2 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family Ribosomal_60s PF00428.19 KKK13728.1 - 0.022 15.3 0.9 0.022 15.3 0.9 2.4 3 0 0 3 3 3 0 60s Acidic ribosomal protein p450 PF00067.22 KKK13729.1 - 1.2e-57 195.7 0.0 1.7e-57 195.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 polyprenyl_synt PF00348.17 KKK13729.1 - 3e-22 78.9 0.0 4.5e-22 78.3 0.0 1.3 1 0 0 1 1 1 1 Polyprenyl synthetase GST_N_3 PF13417.6 KKK13730.1 - 5.7e-09 36.3 0.0 1.2e-08 35.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KKK13730.1 - 1.9e-08 34.5 0.0 3e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KKK13730.1 - 0.0041 17.1 1.0 0.0085 16.1 0.2 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain zf-C3HC PF07967.13 KKK13731.1 - 1.6e-41 141.4 0.0 1.1e-38 132.2 0.0 2.3 2 0 0 2 2 2 2 C3HC zinc finger-like Rsm1 PF08600.10 KKK13731.1 - 1.8e-37 127.4 0.1 5.1e-34 116.3 0.0 2.6 2 0 0 2 2 2 2 Rsm1-like DM PF00751.18 KKK13731.1 - 0.14 12.0 0.1 10 6.1 0.0 2.3 2 0 0 2 2 2 0 DM DNA binding domain COX15-CtaA PF02628.15 KKK13732.1 - 9.7e-115 383.1 3.7 1.2e-114 382.8 3.7 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein Doppel PF11466.8 KKK13733.1 - 0.16 11.7 2.1 3.2 7.5 0.1 2.7 2 0 0 2 2 2 0 Prion-like protein Doppel FAD_binding_3 PF01494.19 KKK13734.1 - 1.8e-17 63.7 0.1 1.7e-06 27.6 0.0 3.1 3 0 0 3 3 3 3 FAD binding domain NAD_binding_8 PF13450.6 KKK13734.1 - 0.00035 20.7 0.2 0.00084 19.5 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KKK13734.1 - 0.0019 17.5 1.1 0.0046 16.2 0.7 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KKK13734.1 - 0.0044 16.1 1.6 0.29 10.2 0.2 2.7 3 0 0 3 3 3 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 KKK13734.1 - 0.0053 15.9 0.1 0.0099 15.0 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KKK13734.1 - 0.0087 15.7 0.6 0.014 15.0 0.6 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KKK13734.1 - 0.04 13.1 1.5 0.072 12.3 0.2 2.1 2 1 1 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KKK13734.1 - 0.055 12.7 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.27 KKK13734.1 - 0.076 13.6 0.3 0.57 10.8 0.1 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase tRNA-synt_2 PF00152.20 KKK13735.1 - 7.5e-78 261.8 0.2 1.1e-77 261.3 0.2 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KKK13735.1 - 1.7e-13 50.4 0.1 3.7e-13 49.3 0.1 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 KKK13735.1 - 4e-05 23.2 0.0 0.043 13.3 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) Dynamin_M PF01031.20 KKK13736.1 - 4e-28 98.4 0.0 2.1e-19 69.8 0.0 2.4 2 0 0 2 2 2 2 Dynamin central region Dynamin_N PF00350.23 KKK13736.1 - 7.7e-24 84.6 0.0 1.6e-23 83.6 0.0 1.6 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 KKK13736.1 - 4.5e-05 23.5 1.1 0.00011 22.3 0.2 2.2 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 KKK13736.1 - 0.0041 17.2 0.0 0.029 14.4 0.0 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase IIGP PF05049.13 KKK13736.1 - 0.018 14.1 0.0 2 7.4 0.0 2.3 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) FRB_dom PF08771.11 KKK13736.1 - 0.037 14.4 4.9 0.4 11.1 0.5 2.8 3 0 0 3 3 3 0 FKBP12-rapamycin binding domain CM_1 PF07736.11 KKK13736.1 - 0.049 14.0 0.2 1.1 9.7 0.0 2.6 3 0 0 3 3 3 0 Chorismate mutase type I Roc PF08477.13 KKK13736.1 - 0.074 13.3 0.0 0.3 11.3 0.0 2.1 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 KKK13736.1 - 0.16 12.3 0.0 1.3 9.3 0.0 2.6 2 0 0 2 2 2 0 AAA ATPase domain AAA PF00004.29 KKK13737.1 - 2.2e-37 128.4 0.0 3.4e-37 127.8 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 KKK13737.1 - 2.1e-07 30.9 0.1 1.8e-06 27.8 0.0 2.7 3 0 0 3 3 2 1 Vps4 C terminal oligomerisation domain AAA_22 PF13401.6 KKK13737.1 - 2.7e-05 24.4 0.5 0.00069 19.9 0.2 2.9 1 1 2 3 3 3 1 AAA domain AAA_2 PF07724.14 KKK13737.1 - 5e-05 23.5 0.0 8.3e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 KKK13737.1 - 6.9e-05 22.6 0.0 0.00012 21.8 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KKK13737.1 - 0.00084 19.3 0.0 0.0024 17.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_lid_3 PF17862.1 KKK13737.1 - 0.0015 18.3 0.2 0.0055 16.5 0.0 2.1 2 0 0 2 2 1 1 AAA+ lid domain AAA_16 PF13191.6 KKK13737.1 - 0.0015 18.9 0.4 0.0015 18.9 0.4 2.4 3 1 0 3 3 1 1 AAA ATPase domain TIP49 PF06068.13 KKK13737.1 - 0.0026 17.0 0.0 0.004 16.4 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain IstB_IS21 PF01695.17 KKK13737.1 - 0.0047 16.7 0.0 0.0081 15.9 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 KKK13737.1 - 0.0048 16.3 0.1 0.0098 15.3 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 KKK13737.1 - 0.0099 16.0 0.0 0.023 14.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 KKK13737.1 - 0.012 14.8 0.0 0.02 14.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_25 PF13481.6 KKK13737.1 - 0.03 13.9 0.1 0.22 11.1 0.0 2.4 2 1 1 3 3 3 0 AAA domain Sigma54_activat PF00158.26 KKK13737.1 - 0.041 13.6 0.0 0.38 10.4 0.0 2.4 2 1 0 2 2 2 0 Sigma-54 interaction domain AAA_14 PF13173.6 KKK13737.1 - 0.066 13.2 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KKK13737.1 - 0.089 12.3 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 KKK13737.1 - 0.095 12.4 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KKK13737.1 - 0.097 12.6 0.0 0.25 11.2 0.0 1.7 1 0 0 1 1 1 0 NACHT domain AAA_18 PF13238.6 KKK13737.1 - 0.13 12.8 0.0 0.37 11.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 KKK13737.1 - 0.26 10.7 0.0 0.5 9.8 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_28 PF13521.6 KKK13737.1 - 0.4 10.9 1.7 0.69 10.1 0.1 2.2 3 0 0 3 3 3 0 AAA domain ENTH PF01417.20 KKK13738.1 - 2.8e-43 146.9 0.0 5.1e-43 146.1 0.0 1.5 1 0 0 1 1 1 1 ENTH domain DUF1720 PF08226.11 KKK13738.1 - 6.4e-05 23.3 27.5 6.4e-05 23.3 27.5 4.8 1 1 2 3 3 3 2 Domain of unknown function (DUF1720) UIM PF02809.20 KKK13738.1 - 0.0011 18.7 8.1 0.039 13.9 2.6 2.6 2 0 0 2 2 2 2 Ubiquitin interaction motif ANTH PF07651.16 KKK13738.1 - 0.018 14.1 0.0 0.029 13.4 0.0 1.3 1 0 0 1 1 1 0 ANTH domain DUF4264 PF14084.6 KKK13738.1 - 0.1 12.3 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4264) WSC PF01822.19 KKK13761.1 - 3.4e-13 49.6 7.7 3.4e-13 49.6 7.7 2.2 2 0 0 2 2 2 1 WSC domain SKG6 PF08693.10 KKK13761.1 - 2.2e-09 36.5 0.5 2.2e-09 36.5 0.5 1.9 2 0 0 2 2 2 1 Transmembrane alpha-helix domain MGC-24 PF05283.11 KKK13761.1 - 0.0002 21.8 6.3 0.00032 21.2 6.3 1.3 1 0 0 1 1 1 1 Multi-glycosylated core protein 24 (MGC-24), sialomucin Alpha_GJ PF03229.13 KKK13761.1 - 0.0011 19.5 3.8 0.002 18.7 3.8 1.4 1 0 0 1 1 1 1 Alphavirus glycoprotein J Trp_oprn_chp PF09534.10 KKK13761.1 - 0.014 15.2 0.4 0.025 14.4 0.0 1.8 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF5305 PF17231.2 KKK13761.1 - 0.024 14.0 0.0 0.04 13.3 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5305) TrbL PF04610.14 KKK13761.1 - 0.05 13.3 1.0 0.075 12.8 1.0 1.2 1 0 0 1 1 1 0 TrbL/VirB6 plasmid conjugal transfer protein L1R_F9L PF02442.17 KKK13761.1 - 0.065 13.1 1.0 0.1 12.5 1.0 1.2 1 0 0 1 1 1 0 Lipid membrane protein of large eukaryotic DNA viruses TrbI PF03743.14 KKK13761.1 - 0.13 12.1 5.0 0.21 11.4 5.0 1.3 1 0 0 1 1 1 0 Bacterial conjugation TrbI-like protein SKN1 PF03935.15 KKK13762.1 - 5e-229 760.8 2.6 6.1e-229 760.5 2.6 1.1 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Sgf11 PF08209.11 KKK13766.1 - 2.5e-10 39.7 1.5 2.7e-10 39.6 0.1 1.8 2 0 0 2 2 2 1 Sgf11 (transcriptional regulation protein) zf-C2HC_2 PF13913.6 KKK13766.1 - 0.02 14.8 0.7 0.038 13.9 0.7 1.5 1 0 0 1 1 1 0 zinc-finger of a C2HC-type zf-C2HC5 PF06221.13 KKK13767.1 - 6.1e-21 74.2 6.1 9.3e-21 73.6 6.1 1.3 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type Mpv17_PMP22 PF04117.12 KKK13768.1 - 1.3e-08 34.9 0.2 3.1e-08 33.7 0.2 1.6 1 0 0 1 1 1 1 Mpv17 / PMP22 family MFS_1 PF07690.16 KKK13769.1 - 4.3e-07 29.2 14.8 4.3e-07 29.2 14.8 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF1761 PF08570.10 KKK13769.1 - 0.052 13.8 11.6 1.8 8.9 1.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1761) Pacifastin_I PF05375.13 KKK13769.1 - 0.071 12.9 0.1 0.11 12.2 0.1 1.3 1 0 0 1 1 1 0 Pacifastin inhibitor (LCMII) DUF2512 PF10710.9 KKK13769.1 - 0.15 11.7 3.8 0.22 11.2 2.3 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF2512) Trep_Strep PF09605.10 KKK13769.1 - 0.87 9.5 15.8 0.85 9.6 9.8 2.3 2 1 0 2 2 2 0 Hypothetical bacterial integral membrane protein (Trep_Strep) RNase_PH PF01138.21 KKK13770.1 - 1.9e-16 60.7 2.6 1.6e-14 54.6 2.6 2.4 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KKK13770.1 - 0.1 12.6 0.0 0.41 10.7 0.0 2.0 1 1 0 1 1 1 0 3' exoribonuclease family, domain 2 Peptidase_A22B PF04258.13 KKK13771.1 - 1.6e-61 208.4 0.5 4.9e-61 206.8 0.5 1.7 1 1 0 1 1 1 1 Signal peptide peptidase SPP PF06550.11 KKK13771.1 - 1.6e-05 24.6 0.8 1.6e-05 24.6 0.8 2.1 2 0 0 2 2 2 1 Signal-peptide peptidase, presenilin aspartyl protease FUSC_2 PF13515.6 KKK13771.1 - 0.051 13.7 0.2 0.051 13.7 0.2 2.4 2 0 0 2 2 2 0 Fusaric acid resistance protein-like FAM176 PF14851.6 KKK13771.1 - 1 9.0 0.0 1 9.0 0.0 3.4 3 1 0 3 3 3 0 FAM176 family Acetyltransf_1 PF00583.25 KKK13772.1 - 0.0025 18.0 0.0 0.022 15.0 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Importin_rep_4 PF18808.1 KKK13772.1 - 3.3 8.0 4.6 6.9 7.0 4.6 1.4 1 0 0 1 1 1 0 Importin repeat NAD_binding_6 PF08030.12 KKK13773.1 - 1.3e-19 70.9 0.0 1.5e-18 67.4 0.0 2.2 1 1 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 KKK13773.1 - 1e-18 67.7 12.4 2.7e-18 66.3 12.4 1.8 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KKK13773.1 - 4.6e-13 49.2 0.0 9e-13 48.3 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 KKK13773.1 - 0.0048 17.5 0.0 0.43 11.2 0.0 2.4 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain AKAP2_C PF15304.6 KKK13773.1 - 0.49 9.6 5.3 0.71 9.1 5.3 1.2 1 0 0 1 1 1 0 A-kinase anchor protein 2 C-terminus DUF604 PF04646.12 KKK13774.1 - 2.8e-08 33.5 0.0 4.5e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF604 Fringe PF02434.16 KKK13774.1 - 1.7e-05 24.4 0.0 3.7e-05 23.3 0.0 1.4 1 1 0 1 1 1 1 Fringe-like Pro_isomerase PF00160.21 KKK13775.1 - 7.2e-54 182.3 0.1 8.2e-54 182.1 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD GDI PF00996.18 KKK13776.1 - 2.9e-25 88.7 0.0 1.3e-24 86.5 0.0 1.8 1 1 0 1 1 1 1 GDP dissociation inhibitor RRM_1 PF00076.22 KKK13777.1 - 3e-17 62.2 0.0 4.4e-17 61.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KKK13777.1 - 0.021 14.9 0.0 0.044 13.9 0.0 1.5 1 1 0 1 1 1 0 RNA recognition motif Limkain-b1 PF11608.8 KKK13777.1 - 0.033 14.2 0.0 0.06 13.4 0.0 1.3 1 0 0 1 1 1 0 Limkain b1 B12D PF06522.11 KKK13778.1 - 0.00073 19.3 0.1 0.0012 18.6 0.1 1.3 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit WD40 PF00400.32 KKK13779.1 - 1.6e-06 28.7 7.9 0.1 13.5 0.0 6.1 6 0 0 6 6 6 2 WD domain, G-beta repeat Sec16_C PF12931.7 KKK13779.1 - 3.3e-05 23.7 0.1 0.00057 19.6 0.1 2.3 1 1 0 1 1 1 1 Sec23-binding domain of Sec16 ANAPC4_WD40 PF12894.7 KKK13779.1 - 0.00052 20.3 1.4 0.0084 16.4 0.1 3.5 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Vps62 PF06101.11 KKK13795.1 - 2.4e-11 42.6 0.6 2.4e-11 42.6 0.6 1.7 2 0 0 2 2 2 1 Vacuolar protein sorting-associated protein 62 TFIIIC_sub6 PF10419.9 KKK13796.1 - 3.8e-24 84.4 0.0 6.4e-24 83.7 0.0 1.4 1 0 0 1 1 1 1 TFIIIC subunit triple barrel domain HECT PF00632.25 KKK13797.1 - 1.6e-96 323.4 0.0 2.4e-96 322.9 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 KKK13797.1 - 1e-33 115.0 23.1 9e-12 44.9 4.0 4.1 4 0 0 4 4 4 3 WW domain C2 PF00168.30 KKK13797.1 - 1.8e-19 69.9 0.0 5.3e-19 68.4 0.0 1.8 1 0 0 1 1 1 1 C2 domain Rrn6 PF10214.9 KKK13797.1 - 0.55 8.7 10.0 0.79 8.1 10.0 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor RRM_1 PF00076.22 KKK13798.1 - 3e-16 59.0 0.0 4.8e-16 58.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KKK13798.1 - 0.013 15.5 0.0 0.023 14.7 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif DUF724 PF05266.14 KKK13798.1 - 0.035 13.9 3.5 0.045 13.6 3.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) ZapB PF06005.12 KKK13798.1 - 0.18 12.2 6.1 0.38 11.2 6.1 1.4 1 0 0 1 1 1 0 Cell division protein ZapB DivIC PF04977.15 KKK13798.1 - 0.22 11.3 5.9 0.36 10.6 5.9 1.3 1 0 0 1 1 1 0 Septum formation initiator Spc7 PF08317.11 KKK13798.1 - 0.27 10.1 8.1 0.37 9.6 8.1 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein OmpH PF03938.14 KKK13798.1 - 1.1 9.6 7.1 1.5 9.2 7.0 1.4 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) UPF0242 PF06785.11 KKK13798.1 - 2.6 8.1 5.2 3.3 7.8 5.2 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Metallophos_2 PF12850.7 KKK13799.1 - 1.7e-11 44.6 0.0 2.4e-11 44.1 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Aminotran_5 PF00266.19 KKK13800.1 - 6.6e-29 101.0 0.0 8.3e-29 100.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V B12-binding PF02310.19 KKK13800.1 - 0.03 14.4 0.0 0.08 13.0 0.0 1.7 1 0 0 1 1 1 0 B12 binding domain Sugar_tr PF00083.24 KKK13841.1 - 6e-77 259.4 22.4 8e-68 229.3 9.7 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KKK13841.1 - 3.2e-22 79.0 20.1 9.1e-22 77.5 20.0 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Golgin_A5 PF09787.9 KKK13866.1 - 0.0022 17.6 52.7 0.037 13.5 18.9 3.3 1 1 2 3 3 3 3 Golgin subfamily A member 5 Cast PF10174.9 KKK13866.1 - 0.0023 16.3 22.0 0.0023 16.3 22.0 2.7 2 1 0 3 3 3 1 RIM-binding protein of the cytomatrix active zone Alkyl_sulf_C PF14864.6 KKK13866.1 - 0.012 15.9 0.1 0.028 14.7 0.1 1.6 1 0 0 1 1 1 0 Alkyl sulfatase C-terminal Rsa3 PF14615.6 KKK13866.1 - 0.036 13.6 0.3 0.1 12.2 0.3 1.7 1 0 0 1 1 1 0 Ribosome-assembly protein 3 Spc7 PF08317.11 KKK13866.1 - 0.22 10.4 52.9 0.67 8.8 13.4 3.3 1 1 2 3 3 3 0 Spc7 kinetochore protein Fez1 PF06818.15 KKK13866.1 - 0.26 11.7 49.2 0.067 13.6 15.8 2.8 2 1 0 2 2 2 0 Fez1 TPR_MLP1_2 PF07926.12 KKK13866.1 - 4 7.5 54.1 4.7 7.3 9.7 4.4 1 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein Filament PF00038.21 KKK13866.1 - 7.7 6.0 49.8 1.5e+02 1.8 49.8 2.3 1 1 0 1 1 1 0 Intermediate filament protein Ribosomal_S4e PF00900.20 KKK13867.1 - 8e-38 128.2 0.2 1.6e-37 127.2 0.2 1.5 1 0 0 1 1 1 1 Ribosomal family S4e 40S_S4_C PF16121.5 KKK13867.1 - 1.4e-24 85.5 0.0 2.4e-24 84.7 0.0 1.4 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus RS4NT PF08071.12 KKK13867.1 - 4.4e-18 65.1 6.6 8.3e-18 64.2 6.6 1.5 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.25 KKK13867.1 - 2.2e-06 27.3 0.0 4e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 S4 domain KOW PF00467.29 KKK13867.1 - 9.4e-05 22.2 4.1 9.4e-05 22.2 4.1 2.6 3 0 0 3 3 3 1 KOW motif RasGEF PF00617.19 KKK13868.1 - 0.00044 20.5 0.0 0.0016 18.7 0.0 1.9 2 1 0 2 2 2 1 RasGEF domain FAD-oxidase_C PF02913.19 KKK13869.1 - 3.5e-63 213.6 0.0 4.5e-63 213.2 0.0 1.1 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 KKK13869.1 - 7.6e-35 119.7 0.0 1.4e-34 118.8 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain SepSecS PF05889.13 KKK13869.1 - 0.12 11.0 0.1 0.32 9.6 0.1 1.6 2 0 0 2 2 2 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS RE_Bsp6I PF09504.10 KKK13869.1 - 0.13 11.9 0.1 0.61 9.7 0.1 2.0 2 0 0 2 2 2 0 Bsp6I restriction endonuclease Semialdhyde_dhC PF02774.18 KKK13870.1 - 3.4e-32 112.0 0.0 4.5e-32 111.6 0.0 1.2 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 KKK13870.1 - 6.2e-30 104.1 0.0 1.3e-29 103.1 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 KKK13870.1 - 0.037 14.3 0.0 0.13 12.5 0.0 1.8 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain DXP_reductoisom PF02670.16 KKK13870.1 - 0.12 13.1 0.0 0.31 11.8 0.0 1.8 2 0 0 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase RdRP PF05183.12 KKK13871.1 - 2.8e-186 620.6 0.0 4.5e-186 620.0 0.0 1.3 1 0 0 1 1 1 1 RNA dependent RNA polymerase RRM_1 PF00076.22 KKK13871.1 - 0.016 15.1 0.0 0.051 13.4 0.0 1.9 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Slu7 PF11708.8 KKK13872.1 - 1.6e-84 283.9 17.3 1.6e-84 283.9 17.3 1.8 2 0 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_4 PF14392.6 KKK13872.1 - 0.017 14.9 0.6 0.037 13.8 0.6 1.6 1 0 0 1 1 1 0 Zinc knuckle DNA_pol_B PF00136.21 KKK13873.1 - 1e-104 350.8 0.0 1.4e-104 350.4 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 KKK13873.1 - 5.7e-19 68.4 0.2 3.8e-12 46.0 0.0 2.4 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 KKK13873.1 - 2e-17 63.4 7.5 2e-17 63.4 7.5 2.2 2 0 0 2 2 2 1 C4-type zinc-finger of DNA polymerase delta zf-RRPl_C4 PF17026.5 KKK13873.1 - 0.99 9.5 3.8 2.4 8.3 3.8 1.6 1 0 0 1 1 1 0 Putative ribonucleoprotein zinc-finger pf C4 type Peptidase_C65 PF10275.9 KKK13874.1 - 2.7e-54 184.2 0.0 3.3e-54 184.0 0.0 1.1 1 0 0 1 1 1 1 Peptidase C65 Otubain Ribosomal_L37e PF01907.19 KKK13875.1 - 7.5e-14 51.6 3.8 1.4e-13 50.8 3.8 1.4 1 0 0 1 1 1 1 Ribosomal protein L37e CytoC_RC PF02276.18 KKK13875.1 - 0.025 13.9 0.1 0.029 13.7 0.1 1.1 1 0 0 1 1 1 0 Photosynthetic reaction centre cytochrome C subunit zf-HYPF PF07503.12 KKK13875.1 - 0.17 11.7 0.5 0.17 11.7 0.5 1.7 2 0 0 2 2 2 0 HypF finger ELP6 PF09807.9 KKK13876.1 - 2.5e-13 50.0 0.0 1.2e-05 24.9 0.0 2.2 2 0 0 2 2 2 2 Elongation complex protein 6 Fungal_trans PF04082.18 KKK13877.1 - 4.1e-26 91.6 0.1 5.9e-26 91.1 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK13877.1 - 8.9e-10 38.5 14.0 1.5e-09 37.8 14.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gal4_dimer PF03902.13 KKK13877.1 - 4.1e-05 23.6 0.5 9.8e-05 22.4 0.2 1.8 2 0 0 2 2 2 1 Gal4-like dimerisation domain DUF4939 PF16297.5 KKK13891.1 - 4.3e-08 33.0 0.0 5.5e-08 32.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) Mur_ligase_M PF08245.12 KKK13907.1 - 8.9e-06 25.8 0.1 1.7e-05 24.9 0.1 1.5 1 1 0 1 1 1 1 Mur ligase middle domain Ribonuc_red_lgC PF02867.15 KKK13908.1 - 3.1e-171 570.5 0.0 3.4e-168 560.5 0.0 2.3 1 1 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 KKK13908.1 - 3.3e-24 84.7 0.0 7.6e-24 83.5 0.0 1.7 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 KKK13908.1 - 1.4e-16 60.8 0.1 3.1e-16 59.7 0.1 1.6 1 0 0 1 1 1 1 ATP cone domain Mucin PF01456.17 KKK13909.1 - 0.06 13.3 19.7 0.091 12.8 19.7 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Opi1 PF08618.10 KKK13909.1 - 0.11 11.7 10.4 0.14 11.4 10.4 1.0 1 0 0 1 1 1 0 Transcription factor Opi1 SprA-related PF12118.8 KKK13909.1 - 0.43 9.7 18.6 0.53 9.4 18.6 1.1 1 0 0 1 1 1 0 SprA-related family Sporozoite_P67 PF05642.11 KKK13909.1 - 6 4.8 13.6 6.7 4.7 13.6 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen PRK PF00485.18 KKK13910.1 - 0.001 18.9 0.0 0.0014 18.4 0.0 1.3 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_33 PF13671.6 KKK13910.1 - 0.062 13.5 0.2 5.4 7.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KKK13910.1 - 0.083 13.4 0.0 0.83 10.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.12 KKK13910.1 - 0.1 12.3 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain DUF3235 PF11574.8 KKK13911.1 - 0.92 10.4 6.5 1.3 9.9 6.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3235) BNIP3 PF06553.12 KKK13911.1 - 2 8.1 8.2 2.7 7.6 8.2 1.2 1 0 0 1 1 1 0 BNIP3 ABC1 PF03109.16 KKK13912.1 - 3.3e-33 114.4 0.0 5.7e-33 113.6 0.0 1.4 1 0 0 1 1 1 1 ABC1 family UCR_TM PF02921.14 KKK13912.1 - 0.16 12.4 0.0 0.48 11.0 0.0 1.8 1 0 0 1 1 1 0 Ubiquinol cytochrome reductase transmembrane region RIO1 PF01163.22 KKK13912.1 - 0.17 11.5 0.0 0.33 10.5 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Pkinase PF00069.25 KKK13913.1 - 9.2e-73 244.9 0.0 3.7e-72 242.9 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK13913.1 - 9.2e-51 172.6 0.0 2e-50 171.5 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KKK13913.1 - 0.0011 17.8 0.2 0.0034 16.2 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase Exo70 PF03081.15 KKK13913.1 - 0.039 13.0 1.2 0.37 9.8 0.2 2.2 2 0 0 2 2 2 0 Exo70 exocyst complex subunit Kinase-like PF14531.6 KKK13913.1 - 0.041 13.2 0.0 0.46 9.8 0.0 2.3 2 0 0 2 2 2 0 Kinase-like GerD PF17898.1 KKK13913.1 - 0.086 12.8 0.4 0.25 11.3 0.4 1.8 1 0 0 1 1 1 0 Spore germination GerD central core domain zf-CCCH_6 PF18585.1 KKK13913.1 - 0.29 11.0 1.2 17 5.4 0.0 3.8 4 0 0 4 4 4 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 2 Fungal_trans PF04082.18 KKK13914.1 - 6.9e-26 90.9 0.3 1.2e-25 90.1 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF4381 PF14316.6 KKK13914.1 - 0.16 12.2 0.1 1.5 9.1 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) Adap_comp_sub PF00928.21 KKK13915.1 - 1.1e-19 70.9 0.0 1.7e-19 70.2 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family muHD PF10291.9 KKK13915.1 - 1.3e-05 24.8 0.0 3.2e-05 23.5 0.0 1.6 1 1 0 1 1 1 1 Muniscin C-terminal mu homology domain Clat_adaptor_s PF01217.20 KKK13915.1 - 0.00021 21.2 0.0 0.00035 20.5 0.0 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain RPM2 PF08579.11 KKK13915.1 - 0.0012 19.2 0.4 0.0023 18.3 0.4 1.3 1 0 0 1 1 1 1 Mitochondrial ribonuclease P subunit (RPM2) Aquarius_N PF16399.5 KKK13915.1 - 0.11 10.5 1.1 0.15 10.1 1.1 1.1 1 0 0 1 1 1 0 Intron-binding protein aquarius N-terminus Mg_trans_NIPA PF05653.14 KKK13916.1 - 2e-88 296.3 16.7 2.6e-85 286.1 12.7 2.0 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.20 KKK13916.1 - 8.7e-07 29.2 30.3 3.6e-06 27.2 1.9 3.2 3 0 0 3 3 3 3 EamA-like transporter family DUF2937 PF11157.8 KKK13916.1 - 0.099 12.3 0.6 0.27 10.9 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) DUF2420 PF10336.9 KKK13917.1 - 7.9e-16 58.0 1.3 1.4e-15 57.2 1.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2420) HEAT_EZ PF13513.6 KKK13918.1 - 1.4e-28 98.9 14.4 3.9e-15 56.0 0.1 10.2 8 2 3 11 11 10 6 HEAT-like repeat HEAT PF02985.22 KKK13918.1 - 6.4e-25 85.1 18.0 2.6e-05 24.1 0.0 12.1 13 0 0 13 13 13 4 HEAT repeat HEAT_2 PF13646.6 KKK13918.1 - 1.9e-15 57.0 2.6 0.0063 16.9 0.0 8.6 6 3 3 9 9 9 2 HEAT repeats Cnd1 PF12717.7 KKK13918.1 - 1e-12 48.4 0.0 0.0015 18.6 0.0 5.3 3 1 1 5 5 5 3 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 KKK13918.1 - 8.1e-08 31.3 0.3 0.00013 20.7 0.0 3.5 2 1 1 3 3 3 2 Adaptin N terminal region MMS19_C PF12460.8 KKK13918.1 - 1.8e-07 30.7 1.0 0.23 10.6 0.0 5.0 4 1 0 5 5 5 3 RNAPII transcription regulator C-terminal Vac14_Fab1_bd PF12755.7 KKK13918.1 - 9e-07 29.4 0.0 0.54 10.9 0.0 6.3 4 3 3 7 7 7 1 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 KKK13918.1 - 1e-05 25.2 0.5 30 4.1 0.0 6.6 5 2 2 7 7 7 0 CLASP N terminal IBN_N PF03810.19 KKK13918.1 - 9.1e-05 22.3 0.2 0.014 15.2 0.0 4.2 2 1 1 3 3 3 1 Importin-beta N-terminal domain Arm PF00514.23 KKK13918.1 - 0.0001 22.2 0.4 1.5 9.0 0.0 5.1 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat Xpo1 PF08389.12 KKK13918.1 - 0.00027 21.0 0.7 2.5 8.2 0.0 4.8 4 1 1 5 5 5 1 Exportin 1-like protein DUF3437 PF11919.8 KKK13918.1 - 0.0025 17.7 0.0 0.27 11.2 0.0 3.8 4 0 0 4 4 4 1 Domain of unknown function (DUF3437) HEAT_PBS PF03130.16 KKK13918.1 - 0.0056 17.2 2.0 14 6.7 0.0 5.3 5 0 0 5 5 4 0 PBS lyase HEAT-like repeat RIX1 PF08167.12 KKK13918.1 - 0.062 13.0 0.2 5.2 6.8 0.0 3.9 5 0 0 5 5 5 0 rRNA processing/ribosome biogenesis Cohesin_HEAT PF12765.7 KKK13918.1 - 0.081 13.2 0.0 15 6.0 0.0 4.2 5 0 0 5 5 4 0 HEAT repeat associated with sister chromatid cohesion TIP120 PF08623.10 KKK13918.1 - 0.15 11.9 0.0 43 3.8 0.0 3.8 4 0 0 4 4 4 0 TATA-binding protein interacting (TIP20) DUF1708 PF08101.11 KKK13918.1 - 0.19 10.8 0.0 0.35 10.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1708) Syja_N PF02383.18 KKK13919.1 - 1.8e-93 313.3 0.0 2.7e-93 312.8 0.0 1.3 1 0 0 1 1 1 1 SacI homology domain hSac2 PF12456.8 KKK13919.1 - 8e-40 135.1 0.0 2.1e-39 133.8 0.0 1.7 1 0 0 1 1 1 1 Inositol phosphatase OMPdecase PF00215.24 KKK13920.1 - 4.3e-10 39.6 0.0 3.1e-06 27.0 0.0 2.3 2 1 0 2 2 2 2 Orotidine 5'-phosphate decarboxylase / HUMPS family TMF_DNA_bd PF12329.8 KKK13922.1 - 0.046 13.7 3.3 0.093 12.7 3.3 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Atg14 PF10186.9 KKK13922.1 - 2.6 7.0 5.3 0.62 9.1 1.8 1.6 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 RRM_1 PF00076.22 KKK13923.1 - 1.6e-41 139.9 0.7 1.4e-19 69.6 0.1 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.6 KKK13923.1 - 3.7e-24 85.6 0.2 1.3e-23 83.9 0.2 2.0 1 0 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_occluded PF16842.5 KKK13923.1 - 4.5e-05 23.2 0.0 0.18 11.7 0.0 3.2 3 0 0 3 3 3 2 Occluded RNA-recognition motif RRM_3 PF08777.11 KKK13923.1 - 0.0084 16.1 0.1 0.054 13.5 0.0 2.4 3 0 0 3 3 3 1 RNA binding motif PHM7_cyt PF14703.6 KKK13923.1 - 0.011 16.0 0.1 4.3 7.5 0.0 3.1 2 1 2 4 4 4 0 Cytosolic domain of 10TM putative phosphate transporter RRM_7 PF16367.5 KKK13923.1 - 0.05 13.7 0.0 1.4 9.1 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif RRM_5 PF13893.6 KKK13923.1 - 0.084 12.5 0.0 0.25 11.0 0.0 1.8 1 1 1 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cyt-b5 PF00173.28 KKK13924.1 - 1.1e-18 67.2 2.2 1.1e-18 67.1 0.2 2.0 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.13 KKK13924.1 - 1.1e-13 51.7 19.0 3.3e-13 50.1 18.4 1.9 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Anth_synt_I_N PF04715.13 KKK13924.1 - 0.031 14.5 0.1 0.075 13.2 0.1 1.6 1 0 0 1 1 1 0 Anthranilate synthase component I, N terminal region COX14 PF14880.6 KKK13924.1 - 0.033 14.0 1.0 0.11 12.3 0.2 2.1 2 0 0 2 2 2 0 Cytochrome oxidase c assembly GPI-anchored PF10342.9 KKK13925.1 - 1.9e-21 76.6 1.6 1.9e-21 76.6 1.6 2.6 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family CCDC84 PF14968.6 KKK13925.1 - 0.19 11.3 5.2 0.24 11.0 5.2 1.1 1 0 0 1 1 1 0 Coiled coil protein 84 Mucin PF01456.17 KKK13925.1 - 0.4 10.7 34.4 0.13 12.3 31.3 1.7 2 0 0 2 2 2 0 Mucin-like glycoprotein Macoilin PF09726.9 KKK13925.1 - 0.58 8.7 12.0 0.62 8.5 12.0 1.1 1 0 0 1 1 1 0 Macoilin family SOG2 PF10428.9 KKK13925.1 - 1.3 8.2 19.1 1.3 8.1 19.1 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein GREB1 PF15782.5 KKK13925.1 - 5.8 3.9 8.8 6.3 3.8 8.8 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SWI-SNF_Ssr4 PF08549.10 KKK13925.1 - 8.9 4.8 8.7 11 4.6 8.7 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) GHMP_kinases_N PF00288.26 KKK13926.1 - 2.1e-15 56.7 1.9 2.4e-15 56.5 0.1 2.1 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KKK13926.1 - 2.3e-07 31.1 0.0 6e-07 29.7 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.9 KKK13926.1 - 0.0035 16.9 0.1 0.0075 15.8 0.1 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature UreF PF01730.16 KKK13926.1 - 0.11 13.1 0.2 0.27 11.8 0.2 1.6 1 0 0 1 1 1 0 UreF Fungal_trans_2 PF11951.8 KKK13927.1 - 5.2e-29 101.2 0.1 1e-17 64.0 0.1 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK13927.1 - 4.7e-09 36.2 7.9 8.2e-09 35.5 7.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PPTA PF01239.22 KKK13928.1 - 2.9e-32 109.4 22.2 3.7e-09 36.0 1.0 5.7 6 0 0 6 6 6 5 Protein prenyltransferase alpha subunit repeat TPR_14 PF13428.6 KKK13928.1 - 0.021 15.6 0.1 0.21 12.5 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF4269 PF14091.6 KKK13928.1 - 0.1 12.9 0.1 0.19 12.0 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4269) PALP PF00291.25 KKK13929.1 - 1.7e-49 168.9 1.2 4.9e-49 167.3 0.7 1.9 2 1 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme DUF3446 PF11928.8 KKK13929.1 - 0.025 14.9 4.5 0.025 14.9 4.5 2.4 2 0 0 2 2 2 0 Early growth response N-terminal domain IMUP PF15761.5 KKK13929.1 - 0.69 10.6 9.2 0.055 14.2 2.4 2.2 2 0 0 2 2 2 0 Immortalisation up-regulated protein SR-25 PF10500.9 KKK13929.1 - 9.8 5.7 13.7 0.65 9.6 8.2 1.7 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein tRNA-synt_1g PF09334.11 KKK13930.1 - 1.2e-93 314.0 0.2 5.1e-92 308.6 0.1 2.3 2 1 0 2 2 2 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 KKK13930.1 - 1.2e-21 76.6 0.1 8.3e-10 37.5 0.0 3.4 2 2 2 4 4 4 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 KKK13930.1 - 1.5e-11 44.2 0.0 0.00015 21.2 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Anticodon_1 PF08264.13 KKK13930.1 - 1.7e-05 24.8 0.0 3.3e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA HTH_AraC PF00165.23 KKK13930.1 - 0.007 16.4 0.1 0.57 10.3 0.0 2.5 1 1 1 2 2 2 1 Bacterial regulatory helix-turn-helix proteins, AraC family NTF2 PF02136.20 KKK13931.1 - 0.00012 22.6 0.3 0.00035 21.1 0.3 1.6 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Mtr2 PF10429.9 KKK13931.1 - 0.0011 19.0 0.1 0.0041 17.1 0.1 1.7 2 0 0 2 2 2 1 Nuclear pore RNA shuttling protein Mtr2 Ish1 PF10281.9 KKK13932.1 - 2.5e-06 27.7 0.1 3.5e-06 27.2 0.1 1.2 1 0 0 1 1 1 1 Putative stress-responsive nuclear envelope protein DUF4129 PF13559.6 KKK13932.1 - 0.053 13.8 1.6 0.082 13.2 1.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4129) SAM_2 PF07647.17 KKK13932.1 - 0.079 13.1 0.1 0.13 12.4 0.1 1.5 1 1 0 1 1 1 0 SAM domain (Sterile alpha motif) HTH_32 PF13565.6 KKK13932.1 - 0.38 11.4 5.6 0.42 11.3 2.8 2.3 1 1 1 2 2 2 0 Homeodomain-like domain Ribosomal_L38e PF01781.18 KKK13933.1 - 6.5e-32 109.4 2.2 7.9e-32 109.2 2.2 1.1 1 0 0 1 1 1 1 Ribosomal L38e protein family Glyco_hydro_61 PF03443.14 KKK13934.1 - 1.4e-68 230.9 0.2 1.7e-68 230.7 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 NARG2_C PF10505.9 KKK13934.1 - 0.14 11.7 0.0 0.17 11.4 0.0 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated gene protein 2 C-terminus HIG_1_N PF04588.13 KKK13936.1 - 2.9e-06 27.4 1.8 2.9e-06 27.4 1.8 1.7 2 0 0 2 2 2 1 Hypoxia induced protein conserved region Troponin-I_N PF11636.8 KKK13936.1 - 0.04 13.9 0.3 0.085 12.8 0.3 1.5 1 0 0 1 1 1 0 Troponin I residues 1-32 PTR2 PF00854.21 KKK13937.1 - 3.3e-78 263.3 8.9 5e-78 262.7 8.9 1.2 1 0 0 1 1 1 1 POT family MFS_1 PF07690.16 KKK13937.1 - 8.5e-05 21.6 23.4 8.5e-05 21.6 23.4 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily NmrA PF05368.13 KKK13938.1 - 8.2e-34 117.2 0.0 1.1e-33 116.8 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KKK13938.1 - 2.9e-11 43.6 0.0 4e-11 43.2 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KKK13938.1 - 0.0001 21.9 0.0 0.0029 17.1 0.0 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KKK13938.1 - 0.035 13.5 0.0 0.05 13.0 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 KKK13938.1 - 0.069 12.3 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 Male sterility protein KR PF08659.10 KKK13938.1 - 0.11 12.4 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 KR domain LtrA PF06772.11 KKK13945.1 - 2.8e-19 69.6 31.1 2.9e-19 69.5 21.8 2.1 2 0 0 2 2 2 2 Bacterial low temperature requirement A protein (LtrA) SH3_10 PF17902.1 KKK13946.1 - 0.13 12.3 0.1 0.33 11.1 0.1 1.6 1 0 0 1 1 1 0 SH3 domain PX PF00787.24 KKK13947.1 - 2.1e-19 69.6 0.0 3e-19 69.1 0.0 1.2 1 0 0 1 1 1 1 PX domain CDP-OH_P_transf PF01066.21 KKK13948.1 - 2.8e-16 60.0 0.1 2.8e-16 60.0 0.1 2.7 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Peptidase_M1 PF01433.20 KKK13949.1 - 0.00012 21.7 0.0 0.00021 20.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 KKK13949.1 - 0.0006 20.0 0.0 0.063 13.5 0.0 2.4 2 0 0 2 2 2 2 Peptidase M1 N-terminal domain LSM PF01423.22 KKK13950.1 - 1.1e-21 76.3 0.3 1.2e-21 76.2 0.3 1.0 1 0 0 1 1 1 1 LSM domain RPN7 PF10602.9 KKK13951.1 - 1.1e-53 181.5 0.1 2.3e-53 180.4 0.1 1.5 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 KKK13951.1 - 1.1e-10 41.9 0.7 3.8e-10 40.2 0.1 2.2 3 0 0 3 3 3 1 PCI domain ELFV_dehydrog PF00208.21 KKK13996.1 - 5.3e-84 281.8 1.9 6.6e-84 281.4 1.9 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 KKK13996.1 - 2.7e-50 169.6 0.0 4.9e-50 168.8 0.0 1.4 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain APG5 PF04106.12 KKK14002.1 - 0.073 12.6 0.1 0.076 12.6 0.1 1.1 1 0 0 1 1 1 0 Autophagy protein Apg5 TPR_2 PF07719.17 KKK14003.1 - 3.7e-06 26.6 2.7 0.02 15.0 0.2 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 KKK14003.1 - 6.2e-06 25.8 1.1 0.062 13.1 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 KKK14003.1 - 0.024 15.3 1.4 0.06 14.0 0.3 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat peroxidase PF00141.23 KKK14005.1 - 2e-45 155.3 0.0 2.9e-45 154.7 0.0 1.2 1 0 0 1 1 1 1 Peroxidase Ribosomal_S13 PF00416.22 KKK14006.1 - 3.8e-13 50.0 0.1 4.3e-13 49.8 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 HHH_6 PF14579.6 KKK14006.1 - 0.08 13.2 0.0 0.083 13.2 0.0 1.1 1 0 0 1 1 1 0 Helix-hairpin-helix motif Actin PF00022.19 KKK14007.1 - 1.4e-148 494.9 0.0 1.6e-148 494.7 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.13 KKK14007.1 - 0.0031 16.4 0.0 6.4 5.5 0.0 3.0 3 0 0 3 3 3 3 MreB/Mbl protein FtsA PF14450.6 KKK14007.1 - 0.045 14.2 0.0 0.11 13.0 0.0 1.8 2 1 0 2 2 2 0 Cell division protein FtsA WD40 PF00400.32 KKK14017.1 - 1.6e-13 50.9 4.6 0.0078 17.0 0.5 5.5 5 0 0 5 5 5 4 WD domain, G-beta repeat SGL PF08450.12 KKK14017.1 - 0.0098 15.5 0.0 0.1 12.1 0.0 2.1 1 1 1 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region ANAPC4_WD40 PF12894.7 KKK14017.1 - 0.049 13.9 0.0 18 5.7 0.0 3.6 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain SARS_X4 PF08779.10 KKK14017.1 - 0.13 12.5 0.0 1.9 8.7 0.0 2.5 2 0 0 2 2 2 0 SARS coronavirus X4 like Rib_5-P_isom_A PF06026.14 KKK14018.1 - 5.3e-44 149.9 0.0 8.5e-44 149.2 0.0 1.3 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.22 KKK14018.1 - 0.0026 17.7 0.1 1.7 8.5 0.0 2.2 1 1 0 2 2 2 2 DeoR C terminal sensor domain ThiF PF00899.21 KKK14019.1 - 9.8e-13 48.0 0.0 4.4e-12 45.9 0.0 2.2 1 1 0 1 1 1 1 ThiF family E1_4HB PF16191.5 KKK14019.1 - 0.029 14.5 0.1 0.49 10.6 0.0 2.8 2 1 0 2 2 2 0 Ubiquitin-activating enzyme E1 four-helix bundle BshC PF10079.9 KKK14019.1 - 0.12 11.1 0.0 0.17 10.6 0.0 1.1 1 0 0 1 1 1 0 Bacillithiol biosynthesis BshC RuvA_C PF07499.13 KKK14019.1 - 0.2 12.2 0.5 1 9.8 0.0 2.5 3 0 0 3 3 3 0 RuvA, C-terminal domain RNase_P_Rpp14 PF01900.19 KKK14020.1 - 9.3e-37 125.4 0.0 1.3e-36 125.0 0.0 1.2 1 0 0 1 1 1 1 Rpp14/Pop5 family ATP_bind_1 PF03029.17 KKK14021.1 - 1.4e-75 254.2 0.0 1.8e-75 253.9 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_31 PF13614.6 KKK14021.1 - 0.0014 18.5 0.0 2.2 8.1 0.0 2.3 1 1 0 2 2 2 2 AAA domain MeaB PF03308.16 KKK14021.1 - 0.0015 17.5 0.0 0.0033 16.4 0.0 1.4 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB MMR_HSR1 PF01926.23 KKK14021.1 - 0.0041 17.2 0.0 0.034 14.2 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_33 PF13671.6 KKK14021.1 - 0.014 15.6 0.0 0.051 13.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 KKK14021.1 - 0.055 13.7 0.0 0.12 12.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain CLP1_P PF16575.5 KKK14021.1 - 0.058 13.2 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_10 PF12846.7 KKK14021.1 - 0.063 12.2 0.0 0.095 11.6 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain Fer4_NifH PF00142.18 KKK14021.1 - 0.15 11.5 0.3 0.43 10.0 0.3 1.8 1 1 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family RNA_helicase PF00910.22 KKK14021.1 - 0.17 12.3 0.0 0.35 11.3 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_17 PF13207.6 KKK14021.1 - 0.28 11.6 0.1 0.28 11.6 0.1 2.3 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.6 KKK14021.1 - 0.35 11.4 2.4 0.51 10.9 0.1 2.2 2 1 0 2 2 2 0 AAA domain RRN3 PF05327.11 KKK14021.1 - 1.2 7.6 3.9 1.8 7.0 3.9 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Cpn10 PF00166.21 KKK14022.1 - 6.1e-19 67.9 0.0 2.5e-15 56.3 0.0 2.0 1 1 1 2 2 2 2 Chaperonin 10 Kd subunit XAP5 PF04921.14 KKK14023.1 - 3.2e-86 289.2 0.1 1e-85 287.6 0.0 1.8 2 0 0 2 2 2 1 XAP5, circadian clock regulator DUF4604 PF15377.6 KKK14023.1 - 0.0042 17.5 6.0 0.0042 17.5 6.0 2.5 3 0 0 3 3 3 1 Domain of unknown function (DUF4604) DHC_N2 PF08393.13 KKK14023.1 - 0.018 14.2 0.9 0.029 13.5 0.9 1.2 1 0 0 1 1 1 0 Dynein heavy chain, N-terminal region 2 DUF5082 PF16888.5 KKK14023.1 - 0.021 15.1 1.0 0.053 13.8 1.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) Exonuc_VII_L PF02601.15 KKK14023.1 - 0.055 13.0 0.8 0.11 12.1 0.8 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit Mod_r PF07200.13 KKK14023.1 - 0.071 13.2 5.6 0.24 11.5 5.6 1.9 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein FTCD_C PF04961.12 KKK14023.1 - 0.086 12.6 1.3 0.17 11.6 1.3 1.5 1 0 0 1 1 1 0 Formiminotransferase-cyclodeaminase SLATT_6 PF18169.1 KKK14023.1 - 0.14 11.7 0.8 0.25 11.0 0.8 1.3 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 6 Syntaxin_2 PF14523.6 KKK14023.1 - 0.25 11.7 5.6 0.64 10.4 5.6 1.7 1 0 0 1 1 1 0 Syntaxin-like protein Fib_alpha PF08702.10 KKK14023.1 - 0.42 10.8 5.6 0.96 9.6 5.6 1.5 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Nup54 PF13874.6 KKK14023.1 - 0.5 10.5 5.3 2.2 8.4 4.1 2.4 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 GAGA_bind PF06217.12 KKK14023.1 - 3.1 8.0 8.0 9.6 6.4 1.8 2.8 2 1 0 2 2 2 0 GAGA binding protein-like family ZapB PF06005.12 KKK14023.1 - 8.9 6.8 12.0 3.7 8.1 7.3 2.7 2 1 0 2 2 1 0 Cell division protein ZapB Fip1 PF05182.13 KKK14024.1 - 3.3e-20 71.3 2.2 5.5e-20 70.6 2.2 1.3 1 0 0 1 1 1 1 Fip1 motif Ribosomal_60s PF00428.19 KKK14024.1 - 0.13 12.8 3.9 0.34 11.5 2.2 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein RNA_pol_3_Rpc31 PF11705.8 KKK14024.1 - 7.5 6.7 9.1 22 5.2 9.1 1.9 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 CoA_binding PF02629.19 KKK14025.1 - 4.7e-19 68.9 0.0 1.8e-18 67.0 0.0 2.1 2 0 0 2 2 2 1 CoA binding domain Citrate_synt PF00285.21 KKK14025.1 - 4.9e-18 65.3 0.1 1.9e-15 56.8 0.1 2.8 1 1 1 2 2 2 2 Citrate synthase, C-terminal domain Ligase_CoA PF00549.19 KKK14025.1 - 3.7e-15 56.1 0.1 6.5e-15 55.3 0.1 1.4 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 KKK14025.1 - 8.7e-07 28.8 0.0 5.6e-06 26.2 0.0 2.2 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain Citrate_bind PF16114.5 KKK14026.1 - 6.9e-88 292.8 0.0 1e-87 292.2 0.0 1.2 1 0 0 1 1 1 1 ATP citrate lyase citrate-binding ATP-grasp_2 PF08442.10 KKK14026.1 - 4.7e-08 32.8 0.0 7.1e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain Reovirus_M2 PF05993.12 KKK14026.1 - 0.064 11.4 0.1 0.099 10.7 0.1 1.2 1 0 0 1 1 1 0 Reovirus major virion structural protein Mu-1/Mu-1C (M2) PX PF00787.24 KKK14029.1 - 1.5e-18 66.8 2.4 7.7e-18 64.5 0.0 2.9 4 0 0 4 4 4 1 PX domain Vps5 PF09325.10 KKK14029.1 - 3.1e-08 33.5 8.1 0.00028 20.5 1.1 2.1 2 0 0 2 2 2 2 Vps5 C terminal like Peptidase_C10 PF01640.17 KKK14029.1 - 0.0043 17.4 0.1 0.01 16.1 0.1 1.6 1 0 0 1 1 1 1 Peptidase C10 family Dicty_REP PF05086.12 KKK14029.1 - 0.17 9.9 1.2 0.26 9.2 1.2 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein AJAP1_PANP_C PF15298.6 KKK14029.1 - 6.5 6.9 11.4 0.63 10.2 6.3 1.8 2 0 0 2 2 2 0 AJAP1/PANP C-terminus Pkinase PF00069.25 KKK14030.1 - 1.3e-44 152.6 0.0 4.6e-42 144.2 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KKK14030.1 - 2.4e-25 89.3 0.0 4e-25 88.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase DUF2428 PF10350.9 KKK14031.1 - 4.7e-65 219.6 0.0 8.5e-65 218.7 0.0 1.5 1 0 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) HEAT PF02985.22 KKK14031.1 - 0.016 15.4 6.3 24 5.5 0.1 5.7 6 0 0 6 6 6 0 HEAT repeat Tim17 PF02466.19 KKK14032.1 - 7.6e-25 87.4 5.6 1e-24 87.1 5.6 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Glyco_hydro_43 PF04616.14 KKK14033.1 - 3.2e-35 121.8 0.1 4.9e-35 121.2 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 DUF5313 PF17240.2 KKK14033.1 - 0.057 13.9 0.2 0.11 13.0 0.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5313) FAM35_C PF15793.5 KKK14036.1 - 0.026 13.9 0.2 0.035 13.5 0.2 1.1 1 0 0 1 1 1 0 Protein family FAM35, C-terminal DUF996 PF06195.13 KKK14037.1 - 2 8.7 15.6 3.2 8.0 6.3 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF996) Phosphoesterase PF04185.14 KKK14038.1 - 8.6e-35 120.6 4.0 5.1e-34 118.0 4.0 1.9 1 1 0 1 1 1 1 Phosphoesterase family HIF-1a_CTAD PF08778.10 KKK14038.1 - 0.073 12.7 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 HIF-1 alpha C terminal transactivation domain Mgm101p PF06420.12 KKK14047.1 - 2.9e-85 284.0 0.0 3.6e-85 283.7 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 CHCH PF06747.13 KKK14048.1 - 5.3e-07 29.6 7.6 7.4e-07 29.2 7.6 1.2 1 0 0 1 1 1 1 CHCH domain CX9C PF16860.5 KKK14048.1 - 0.0094 15.9 1.0 0.3 11.1 0.2 2.2 2 0 0 2 2 2 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Toxin_25 PF08095.11 KKK14048.1 - 0.02 14.8 0.6 0.02 14.8 0.6 2.1 2 1 0 2 2 2 0 Hefutoxin family Cmc1 PF08583.10 KKK14048.1 - 0.02 14.9 5.3 0.049 13.7 5.3 1.6 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like COX17 PF05051.13 KKK14048.1 - 0.13 12.7 2.6 0.19 12.1 2.6 1.2 1 0 0 1 1 1 0 Cytochrome C oxidase copper chaperone (COX17) Zn_clus PF00172.18 KKK14049.1 - 9e-08 32.1 11.8 1.8e-07 31.2 11.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MS_channel PF00924.18 KKK14050.1 - 4.6e-21 75.3 1.2 7.8e-21 74.6 1.2 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.32 KKK14050.1 - 0.00011 21.4 0.4 0.00028 20.2 0.4 1.7 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 KKK14050.1 - 0.00049 19.8 0.0 0.0014 18.3 0.0 1.8 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 KKK14050.1 - 0.0068 16.8 0.1 0.021 15.3 0.1 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 KKK14050.1 - 0.042 13.4 0.1 0.13 11.8 0.1 1.8 1 0 0 1 1 1 0 EF hand LRR19-TM PF15176.6 KKK14050.1 - 0.068 13.2 0.0 0.34 10.9 0.0 2.2 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain CDT1_C PF16679.5 KKK14050.1 - 0.72 10.3 0.0 0.72 10.3 0.0 2.2 3 0 0 3 3 3 0 DNA replication factor Cdt1 C-terminal domain YjbE PF11106.8 KKK14050.1 - 0.77 10.0 3.9 2.6 8.3 3.9 1.9 1 0 0 1 1 1 0 Exopolysaccharide production protein YjbE TANGO2 PF05742.12 KKK14051.1 - 1.2e-71 241.7 0.0 1.5e-71 241.5 0.0 1.0 1 0 0 1 1 1 1 Transport and Golgi organisation 2 TB2_DP1_HVA22 PF03134.19 KKK14052.1 - 7.4e-14 51.4 4.5 1.3e-13 50.7 4.5 1.4 1 0 0 1 1 1 1 TB2/DP1, HVA22 family BPL_N PF09825.9 KKK14053.1 - 4.6e-126 420.9 0.0 6e-126 420.5 0.0 1.1 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.19 KKK14053.1 - 8.2e-26 90.5 0.1 1.3e-25 89.8 0.1 1.3 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_C PF02237.17 KKK14053.1 - 0.0002 21.2 0.0 0.00038 20.3 0.0 1.5 1 0 0 1 1 1 1 Biotin protein ligase C terminal domain p450 PF00067.22 KKK14054.1 - 1.2e-45 156.2 0.0 1.7e-45 155.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF1768 PF08719.11 KKK14055.1 - 2e-28 99.7 0.0 2.9e-28 99.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) ADH_zinc_N PF00107.26 KKK14056.1 - 5.4e-10 39.4 0.0 9.4e-10 38.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KKK14056.1 - 9.2e-07 28.7 0.0 6.1e-06 26.1 0.0 2.0 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KKK14056.1 - 0.0018 19.3 0.0 0.0032 18.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 KKK14056.1 - 0.0075 16.2 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase zf-RING_2 PF13639.6 KKK14057.1 - 1.9e-13 50.5 5.7 3.2e-13 49.8 5.7 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KKK14057.1 - 4.2e-10 39.2 2.5 7.5e-10 38.4 2.5 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KKK14057.1 - 7.9e-09 35.2 6.1 1.3e-08 34.5 6.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KKK14057.1 - 1.4e-07 31.3 3.6 2.1e-07 30.7 3.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KKK14057.1 - 1.7e-06 28.2 7.3 4.7e-06 26.8 7.3 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KKK14057.1 - 3.8e-05 23.6 2.5 6.5e-05 22.8 2.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KKK14057.1 - 0.00014 21.7 8.3 0.0014 18.5 7.6 2.4 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 KKK14057.1 - 0.00014 21.6 2.1 0.00024 20.9 2.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KKK14057.1 - 0.00097 19.1 5.1 0.0019 18.2 4.7 1.7 1 1 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 KKK14057.1 - 0.0016 18.4 2.8 0.0034 17.4 2.8 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 KKK14057.1 - 0.0065 16.2 4.1 0.012 15.4 4.1 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING-like PF08746.11 KKK14057.1 - 0.16 12.3 2.0 0.29 11.5 2.0 1.4 1 0 0 1 1 1 0 RING-like domain Zn_ribbon_17 PF17120.5 KKK14057.1 - 0.41 10.3 2.7 0.68 9.6 2.7 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4_4 PF15227.6 KKK14057.1 - 0.46 10.7 5.6 0.92 9.7 5.6 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.8 KKK14057.1 - 0.74 10.0 4.3 5.2 7.3 4.3 2.4 1 1 0 1 1 1 0 FANCL C-terminal domain PHD PF00628.29 KKK14057.1 - 4.8 7.2 5.0 21 5.1 5.2 2.0 1 1 1 2 2 2 0 PHD-finger Aminotran_1_2 PF00155.21 KKK14067.1 - 1.8e-72 244.6 0.0 2e-72 244.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Abhydrolase_3 PF07859.13 KKK14068.1 - 3.6e-10 40.1 0.2 8.9e-05 22.4 0.0 2.0 1 1 1 2 2 2 2 alpha/beta hydrolase fold Lyase_1 PF00206.20 KKK14069.1 - 2.3e-115 385.3 0.0 3.1e-115 384.9 0.0 1.2 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 KKK14069.1 - 8.4e-21 74.1 0.0 2.3e-20 72.7 0.0 1.8 1 0 0 1 1 1 1 Fumarase C C-terminus Acetyltransf_1 PF00583.25 KKK14070.1 - 6e-11 42.6 0.1 7.7e-11 42.3 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KKK14070.1 - 6.3e-09 35.8 0.0 8.7e-09 35.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KKK14070.1 - 3e-07 30.8 0.3 4.5e-07 30.2 0.3 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Ribosomal_S30 PF04758.14 KKK14071.1 - 4.6e-12 45.9 1.7 6e-12 45.6 1.7 1.2 1 0 0 1 1 1 1 Ribosomal protein S30 Ecl1 PF12855.7 KKK14072.1 - 2.4e-11 45.1 17.5 3.9e-11 44.4 17.5 1.3 1 1 0 1 1 1 1 ECL1/2/3 zinc binding proteins MoCF_biosynth PF00994.24 KKK14073.1 - 2.2e-36 124.7 0.0 3.7e-36 123.9 0.0 1.3 1 0 0 1 1 1 1 Probable molybdopterin binding domain CinA_KH PF18146.1 KKK14073.1 - 0.017 15.2 0.0 0.054 13.7 0.0 1.7 2 0 0 2 2 2 0 Damage-inducible protein CinA KH domain AMPK1_CBM PF16561.5 KKK14076.1 - 4.3e-29 100.6 0.1 7.9e-29 99.7 0.1 1.4 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase AMPKBI PF04739.15 KKK14076.1 - 1.6e-25 89.1 1.1 5.1e-25 87.5 1.1 1.9 1 0 0 1 1 1 1 5'-AMP-activated protein kinase beta subunit, interaction domain EPL1 PF10513.9 KKK14078.1 - 3.5e-21 76.2 0.5 3.5e-21 76.2 0.5 2.9 2 1 1 3 3 3 1 Enhancer of polycomb-like A_deaminase_N PF08451.11 KKK14078.1 - 6 7.2 7.9 3.3 8.1 0.7 3.1 3 0 0 3 3 3 0 Adenosine/AMP deaminase N-terminal SET PF00856.28 KKK14079.1 - 3.3e-22 79.7 0.0 7.5e-22 78.5 0.0 1.6 2 0 0 2 2 2 1 SET domain Rubis-subs-bind PF09273.11 KKK14079.1 - 2e-12 47.9 3.2 2.3e-12 47.7 2.1 1.8 1 1 0 1 1 1 1 Rubisco LSMT substrate-binding LEM PF03020.15 KKK14079.1 - 0.0023 17.4 0.1 0.0085 15.6 0.1 2.0 1 0 0 1 1 1 1 LEM domain Peptidase_M22 PF00814.25 KKK14080.1 - 1.4e-84 284.0 0.0 1.6e-84 283.8 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family Carbam_trans_N PF02543.15 KKK14080.1 - 0.05 13.3 0.0 0.92 9.1 0.0 2.1 2 0 0 2 2 2 0 Carbamoyltransferase N-terminus EF-hand_1 PF00036.32 KKK14081.1 - 1.1e-27 93.5 13.8 6.5e-08 31.6 0.8 4.4 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KKK14081.1 - 1.5e-21 76.6 9.2 4.4e-13 49.5 1.9 2.6 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KKK14081.1 - 1e-20 71.8 9.0 1.4e-05 24.6 0.1 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 KKK14081.1 - 1e-17 62.8 11.8 5.9e-06 25.5 0.4 4.4 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 KKK14081.1 - 4.3e-13 48.9 13.2 0.00018 21.3 0.7 4.2 3 2 1 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KKK14081.1 - 5.2e-07 30.0 0.0 0.0046 17.3 0.1 2.3 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 KKK14081.1 - 0.00082 19.3 11.6 0.57 10.2 0.5 4.1 1 1 3 4 4 4 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 KKK14081.1 - 0.03 14.6 0.3 0.98 9.8 0.1 2.8 2 1 1 3 3 3 0 EF-hand domain Pkinase PF00069.25 KKK14082.1 - 7e-23 81.3 0.0 3.8e-22 78.9 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK14082.1 - 2.5e-06 27.0 0.3 5e-05 22.7 0.3 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Glyco_hydro_3_C PF01915.22 KKK14083.1 - 1e-44 152.9 0.0 1.5e-44 152.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KKK14083.1 - 1.7e-30 106.5 0.0 2.6e-30 105.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KKK14083.1 - 7.3e-10 38.8 0.0 1.3e-09 38.0 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Cleaved_Adhesin PF07675.11 KKK14083.1 - 0.029 14.3 0.1 0.062 13.2 0.1 1.5 1 0 0 1 1 1 0 Cleaved Adhesin Domain Fungal_trans_2 PF11951.8 KKK14084.1 - 1e-13 50.9 0.1 6.2e-13 48.3 0.1 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK14084.1 - 2.7e-06 27.4 12.9 2.7e-06 27.4 12.9 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Metallophos PF00149.28 KKK14085.1 - 1.4e-16 61.7 0.3 2.3e-16 60.9 0.3 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Pur_ac_phosph_N PF16656.5 KKK14085.1 - 8.4e-14 51.9 1.5 1.9e-13 50.8 1.5 1.5 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain Metallophos_C PF14008.6 KKK14085.1 - 9.2e-14 52.1 0.0 2.1e-13 50.9 0.0 1.6 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C fn3 PF00041.21 KKK14085.1 - 0.026 14.9 1.7 0.059 13.7 1.7 1.5 1 0 0 1 1 1 0 Fibronectin type III domain PhoD_N PF16655.5 KKK14085.1 - 0.026 15.0 0.3 0.13 12.8 0.1 2.1 2 0 0 2 2 2 0 PhoD-like phosphatase, N-terminal domain Cupin_2 PF07883.11 KKK14085.1 - 0.081 12.6 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 Cupin domain SIMPL PF04402.14 KKK14087.1 - 1.3e-20 74.7 0.0 1.5e-20 74.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF541) MFS_1 PF07690.16 KKK14088.1 - 4.5e-25 88.3 52.7 4.6e-15 55.4 36.4 3.5 3 1 0 3 3 3 2 Major Facilitator Superfamily TMC PF07810.13 KKK14088.1 - 1.1 9.8 7.4 0.13 12.8 2.1 2.2 2 0 0 2 2 2 0 TMC domain DUF3431 PF11913.8 KKK14089.1 - 1.4e-67 227.7 0.0 1.7e-67 227.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) Ysc84 PF04366.12 KKK14090.1 - 8.7e-25 86.9 0.0 1.6e-24 86.1 0.0 1.3 1 0 0 1 1 1 1 Las17-binding protein actin regulator Epimerase PF01370.21 KKK14091.1 - 3.1e-13 49.7 1.3 3.4e-12 46.3 1.3 2.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KKK14091.1 - 8.2e-10 38.6 0.2 1.2e-06 28.2 0.0 2.5 1 1 1 2 2 2 2 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 KKK14091.1 - 6.6e-06 25.5 0.0 0.013 14.6 0.0 2.1 1 1 1 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.6 KKK14091.1 - 1.4e-05 25.1 0.0 4e-05 23.6 0.0 1.7 2 0 0 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 KKK14091.1 - 0.00014 21.5 0.0 0.00025 20.7 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.19 KKK14091.1 - 0.0013 17.8 0.1 0.093 11.7 0.1 2.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 KKK14091.1 - 0.0054 16.2 0.0 0.013 14.9 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase Polysacc_synt_2 PF02719.15 KKK14091.1 - 0.025 13.7 0.2 0.14 11.3 0.1 1.8 1 1 1 2 2 2 0 Polysaccharide biosynthesis protein Zn_clus PF00172.18 KKK14092.1 - 2.1e-08 34.1 11.8 4.6e-08 33.0 11.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 KKK14093.1 - 6.1e-33 114.2 56.0 1.7e-24 86.4 30.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KKK14093.1 - 0.00014 20.9 43.2 0.0048 15.8 16.5 3.1 2 1 1 3 3 3 3 Sugar (and other) transporter PARP_reg PF02877.14 KKK14094.1 - 6.8e-35 120.1 0.1 1.3e-34 119.2 0.1 1.5 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain PARP PF00644.20 KKK14094.1 - 8.3e-35 120.1 0.0 4.6e-34 117.7 0.0 2.0 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain WGR PF05406.15 KKK14094.1 - 3.6e-10 39.8 0.9 7.5e-10 38.7 0.9 1.5 1 0 0 1 1 1 1 WGR domain BRCT PF00533.26 KKK14094.1 - 7.3e-08 32.7 0.0 1.8e-07 31.4 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 KKK14094.1 - 3.1e-05 23.8 0.2 6.6e-05 22.8 0.2 1.6 1 0 0 1 1 1 1 twin BRCT domain BRCT_2 PF16589.5 KKK14094.1 - 0.0016 18.8 0.0 0.0034 17.8 0.0 1.6 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain Pyridoxal_deC PF00282.19 KKK14095.1 - 1.1e-97 327.1 0.0 1.5e-97 326.7 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.21 KKK14095.1 - 0.0038 16.6 0.0 0.0053 16.1 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Ank_2 PF12796.7 KKK14096.1 - 1e-45 154.2 0.5 7.9e-14 52.0 0.0 3.9 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KKK14096.1 - 4.9e-36 122.7 2.2 2e-10 41.0 0.0 4.8 3 2 3 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 KKK14096.1 - 2.9e-30 103.9 5.0 2.2e-07 31.0 0.0 5.9 2 2 4 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 KKK14096.1 - 1e-27 93.1 0.5 3.9e-05 23.7 0.0 7.4 7 0 0 7 7 7 4 Ankyrin repeat Ank PF00023.30 KKK14096.1 - 1.6e-26 91.5 11.1 4.8e-05 23.6 0.0 7.2 7 0 0 7 7 7 5 Ankyrin repeat F-box-like PF12937.7 KKK14096.1 - 0.077 12.9 0.6 0.18 11.7 0.6 1.6 1 0 0 1 1 1 0 F-box-like Fungal_trans PF04082.18 KKK14097.1 - 2.6e-11 43.1 0.1 4.8e-11 42.2 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK14097.1 - 0.14 12.3 6.7 0.26 11.4 6.7 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Arrestin_C PF02752.22 KKK14098.1 - 5.7e-11 43.0 0.2 2e-10 41.2 0.1 1.8 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain MFS_1 PF07690.16 KKK14099.1 - 4.3e-51 173.9 46.1 4.3e-51 173.9 46.1 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KKK14099.1 - 4.3e-21 75.0 22.8 6.5e-21 74.4 22.8 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KKK14099.1 - 2e-14 53.4 7.8 2e-14 53.4 7.8 2.7 2 1 0 2 2 2 1 Sugar (and other) transporter DUF543 PF04418.12 KKK14099.1 - 2 8.5 9.7 11 6.1 0.3 4.1 3 1 1 4 4 4 0 Domain of unknown function (DUF543) OATP PF03137.20 KKK14099.1 - 3.7 5.7 12.4 0.097 10.9 1.3 2.7 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family FAD_binding_2 PF00890.24 KKK14100.1 - 6.4e-62 210.0 0.6 7.5e-62 209.7 0.6 1.0 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KKK14100.1 - 1.8e-10 41.0 0.2 1.7e-08 34.4 0.1 2.7 1 1 1 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KKK14100.1 - 1.7e-08 34.1 0.3 1.3e-07 31.2 0.2 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KKK14100.1 - 9.7e-07 28.9 0.2 3.7e-06 27.1 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KKK14100.1 - 4.1e-06 25.8 0.8 0.016 13.9 0.2 3.1 3 0 0 3 3 3 2 HI0933-like protein GIDA PF01134.22 KKK14100.1 - 0.00016 20.9 3.6 0.023 13.8 0.3 2.9 3 0 0 3 3 3 2 Glucose inhibited division protein A FAD_binding_3 PF01494.19 KKK14100.1 - 0.00065 19.1 1.0 0.001 18.4 0.4 1.6 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 KKK14100.1 - 0.0014 18.0 0.7 0.013 14.8 0.2 2.2 2 0 0 2 2 2 1 Thi4 family FAD_oxidored PF12831.7 KKK14100.1 - 0.0053 16.1 0.4 0.012 15.0 0.2 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KKK14100.1 - 0.0075 15.6 0.1 2.7 7.1 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KKK14100.1 - 0.079 13.5 0.4 0.5 11.0 0.1 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 KKK14100.1 - 0.12 12.3 0.1 0.21 11.5 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lycopene_cycl PF05834.12 KKK14100.1 - 0.14 11.2 0.5 0.38 9.8 0.2 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_7 PF13241.6 KKK14100.1 - 0.17 12.3 0.0 0.39 11.2 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding ADH_zinc_N_2 PF13602.6 KKK14101.1 - 2.6e-16 60.9 0.1 4.6e-16 60.1 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KKK14101.1 - 5.7e-12 45.7 0.1 1.1e-11 44.8 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KKK14101.1 - 0.0001 22.1 0.0 0.00023 21.0 0.0 1.6 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.25 KKK14101.1 - 0.0061 16.0 0.1 0.032 13.7 0.1 2.0 1 1 1 2 2 2 1 short chain dehydrogenase Epimerase PF01370.21 KKK14101.1 - 0.059 12.8 0.1 0.085 12.3 0.1 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KKK14101.1 - 0.071 12.2 0.0 0.17 11.0 0.0 1.6 1 0 0 1 1 1 0 RmlD substrate binding domain bZIP_1 PF00170.21 KKK14102.1 - 6e-06 26.3 0.6 1.3e-05 25.2 0.6 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KKK14102.1 - 0.095 12.8 1.2 0.23 11.5 1.2 1.6 1 0 0 1 1 1 0 Basic region leucine zipper CDC45 PF02724.14 KKK14102.1 - 0.14 10.4 1.1 0.19 10.0 1.1 1.1 1 0 0 1 1 1 0 CDC45-like protein FA_hydroxylase PF04116.13 KKK14103.1 - 4.7e-25 88.5 14.4 4.7e-25 88.5 14.4 2.3 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily TPR_MLP1_2 PF07926.12 KKK14103.1 - 0.23 11.5 0.2 0.54 10.3 0.2 1.4 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein PH_6 PF15406.6 KKK14104.1 - 1.3e-37 128.4 1.2 1.3e-37 128.4 1.2 2.9 2 1 0 2 2 2 1 Pleckstrin homology domain PH PF00169.29 KKK14104.1 - 2.7e-08 34.2 0.0 6.8e-08 33.0 0.0 1.7 1 1 0 1 1 1 1 PH domain PH_13 PF16652.5 KKK14104.1 - 0.058 13.2 0.1 0.097 12.5 0.1 1.4 1 0 0 1 1 1 0 Pleckstrin homology domain Pkinase PF00069.25 KKK14118.1 - 7.9e-31 107.4 0.0 1.3e-30 106.6 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK14118.1 - 1.6e-15 57.1 0.0 1.2e-14 54.3 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 KKK14118.1 - 0.0052 15.8 0.0 0.0079 15.2 0.0 1.2 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase APH PF01636.23 KKK14118.1 - 0.023 14.6 0.0 0.037 14.0 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 KKK14118.1 - 0.029 13.7 0.0 0.045 13.1 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KKK14118.1 - 0.035 13.7 0.1 0.071 12.7 0.1 1.4 1 0 0 1 1 1 0 RIO1 family JmjC PF02373.22 KKK14125.1 - 4.8e-09 36.7 0.0 5.1e-08 33.3 0.0 2.4 1 1 0 1 1 1 1 JmjC domain, hydroxylase JHD PF17811.1 KKK14125.1 - 5.1e-09 36.6 0.3 1e-08 35.6 0.3 1.5 1 0 0 1 1 1 1 Jumonji helical domain Cupin_8 PF13621.6 KKK14125.1 - 2.8e-08 33.8 0.0 7.2e-08 32.5 0.0 1.7 1 0 0 1 1 1 1 Cupin-like domain PHD PF00628.29 KKK14125.1 - 4.3e-08 32.9 4.4 4.3e-08 32.9 4.4 2.7 3 0 0 3 3 3 1 PHD-finger PHD_2 PF13831.6 KKK14125.1 - 0.0054 16.3 4.4 0.0069 15.9 2.4 2.4 2 0 0 2 2 2 1 PHD-finger Dickkopf_N PF04706.12 KKK14125.1 - 0.62 10.6 9.8 6.8 7.3 0.8 3.0 2 0 0 2 2 2 0 Dickkopf N-terminal cysteine-rich region Zn_clus PF00172.18 KKK14125.1 - 3.1 8.0 28.3 0.16 12.1 5.2 3.2 3 0 0 3 3 3 0 Fungal Zn(2)-Cys(6) binuclear cluster domain AA_permease PF00324.21 KKK14130.1 - 2.9e-52 177.9 43.1 3.7e-32 111.6 20.8 3.0 2 1 0 2 2 2 2 Amino acid permease AA_permease_2 PF13520.6 KKK14130.1 - 3.1e-19 69.1 46.0 2e-18 66.5 45.0 3.0 1 1 0 1 1 1 1 Amino acid permease TauD PF02668.16 KKK14132.1 - 3.9e-13 49.8 1.3 7.5e-13 48.9 1.3 1.5 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 KKK14132.1 - 8.9e-05 21.7 0.0 0.00014 21.1 0.0 1.3 1 0 0 1 1 1 1 CsiD AMP-binding PF00501.28 KKK14133.1 - 0.12 10.9 0.0 0.16 10.5 0.0 1.2 1 0 0 1 1 1 0 AMP-binding enzyme SLT_beta PF02258.16 KKK14134.1 - 0.13 12.3 0.0 0.23 11.5 0.0 1.3 1 0 0 1 1 1 0 Shiga-like toxin beta subunit ACOX PF01756.19 KKK14135.1 - 3.9e-44 150.4 0.1 1.4e-43 148.5 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 KKK14135.1 - 5.2e-27 94.9 0.2 1.1e-26 93.9 0.2 1.6 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_1 PF00441.24 KKK14135.1 - 1.7e-05 25.0 0.7 0.0028 17.9 0.7 2.5 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KKK14135.1 - 0.0001 22.4 0.0 0.0014 18.8 0.0 2.6 2 1 1 3 3 3 1 Acyl-CoA dehydrogenase, middle domain DIOX_N PF14226.6 KKK14136.1 - 1.9e-28 99.6 0.1 2.9e-28 99.0 0.1 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KKK14136.1 - 3.1e-21 75.7 0.0 6.7e-21 74.7 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily p450 PF00067.22 KKK14137.1 - 1.1e-76 258.5 0.0 1.2e-76 258.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_25 PF13649.6 KKK14138.1 - 6.9e-07 29.9 0.0 2.1e-06 28.3 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KKK14138.1 - 0.0013 19.3 0.0 0.0028 18.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Pox_MCEL PF03291.16 KKK14138.1 - 0.0037 16.4 0.0 0.0056 15.8 0.0 1.2 1 0 0 1 1 1 1 mRNA capping enzyme Methyltransf_31 PF13847.6 KKK14138.1 - 0.005 16.6 0.0 0.0073 16.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MFS_1 PF07690.16 KKK14139.1 - 1.3e-28 99.9 67.1 1.9e-21 76.4 30.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1279 PF06916.13 KKK14139.1 - 0.019 15.5 1.1 0.019 15.5 1.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1279) Abhydrolase_3 PF07859.13 KKK14140.1 - 2.2e-46 158.4 0.0 2.8e-46 158.1 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KKK14140.1 - 2.1e-10 40.1 0.6 6.4e-10 38.5 0.6 1.6 1 1 0 1 1 1 1 Carboxylesterase family Say1_Mug180 PF10340.9 KKK14140.1 - 0.22 10.3 0.0 0.34 9.7 0.0 1.3 1 0 0 1 1 1 0 Steryl acetyl hydrolase Glyco_hydro_43 PF04616.14 KKK14143.1 - 7.2e-58 196.2 3.0 1e-57 195.7 3.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 KKK14143.1 - 3.4e-32 111.8 0.0 9.2e-32 110.4 0.0 1.7 1 1 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain Glyco_hydro_2_N PF02837.18 KKK14143.1 - 0.05 13.5 0.1 0.092 12.6 0.1 1.4 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, sugar binding domain DUF5357 PF17310.2 KKK14143.1 - 0.16 10.5 0.0 0.23 10.0 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5357) Zn_clus PF00172.18 KKK14144.1 - 2.8e-07 30.6 6.2 2.8e-07 30.6 6.2 2.6 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CAP_N PF01213.19 KKK14144.1 - 0.16 11.4 8.9 0.053 13.0 3.8 2.2 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal PRIMA1 PF16101.5 KKK14144.1 - 0.47 10.5 7.8 0.67 10.0 2.4 2.5 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 Mito_fiss_reg PF05308.11 KKK14144.1 - 0.6 10.1 5.0 0.1 12.7 1.2 1.7 2 0 0 2 2 2 0 Mitochondrial fission regulator AMP-binding PF00501.28 KKK14145.1 - 1.2e-90 304.1 0.0 1.6e-90 303.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KKK14145.1 - 2.3e-14 54.1 0.0 4.8e-14 53.1 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Pyridoxal_deC PF00282.19 KKK14146.1 - 3.3e-68 230.1 0.0 2.5e-54 184.4 0.0 2.1 2 0 0 2 2 2 2 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.21 KKK14146.1 - 1.4e-07 31.1 0.0 2e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 KKK14146.1 - 4.5e-07 29.2 0.0 1e-06 28.0 0.0 1.5 2 0 0 2 2 2 1 Aminotransferase class-V AMP-binding PF00501.28 KKK14147.1 - 5.2e-57 193.3 0.0 7.2e-57 192.9 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 KKK14147.1 - 2.9e-40 138.3 0.0 1.1e-30 106.7 0.0 2.8 2 1 0 2 2 2 2 Condensation domain PP-binding PF00550.25 KKK14147.1 - 4.2e-08 33.4 0.0 1e-07 32.2 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KKK14147.1 - 0.014 16.4 0.0 0.039 14.9 0.0 1.8 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain Condensation PF00668.20 KKK14148.1 - 9.9e-36 123.4 0.0 1.7e-35 122.6 0.0 1.4 1 1 0 1 1 1 1 Condensation domain PP-binding PF00550.25 KKK14148.1 - 2.5e-12 47.0 0.2 9.1e-12 45.2 0.2 2.1 1 0 0 1 1 1 1 Phosphopantetheine attachment site Transferase PF02458.15 KKK14148.1 - 0.059 12.0 0.0 0.13 10.9 0.0 1.5 1 0 0 1 1 1 0 Transferase family Adap_comp_sub PF00928.21 KKK14149.1 - 3.8e-62 210.0 0.0 1e-51 175.8 0.0 2.1 2 0 0 2 2 2 2 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KKK14149.1 - 0.00012 22.0 0.4 0.00024 21.0 0.4 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain TFIIF_alpha PF05793.12 KKK14149.1 - 0.2 10.2 10.3 0.28 9.7 10.3 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) FTCD_C PF04961.12 KKK14149.1 - 0.22 11.3 1.0 0.4 10.4 1.0 1.3 1 0 0 1 1 1 0 Formiminotransferase-cyclodeaminase SPT6_acidic PF14632.6 KKK14149.1 - 1.3 9.6 6.5 2.3 8.9 6.5 1.3 1 0 0 1 1 1 0 Acidic N-terminal SPT6 BTB_2 PF02214.22 KKK14150.1 - 3.8e-08 33.6 0.0 7.2e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KKK14150.1 - 6.1e-05 23.2 0.0 0.0001 22.5 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain DUF4588 PF15251.6 KKK14151.1 - 1.6e-06 28.1 0.2 1.6e-06 28.1 0.2 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF4588) Glyco_tranf_2_2 PF10111.9 KKK14151.1 - 0.1 12.0 0.0 0.15 11.5 0.0 1.1 1 0 0 1 1 1 0 Glycosyltransferase like family 2 MGC-24 PF05283.11 KKK14151.1 - 9.1 6.7 8.1 2.2 8.7 3.3 2.1 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF4536 PF15055.6 KKK14152.1 - 3e-07 30.6 1.0 3e-07 30.6 1.0 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF4536) MOZ_SAS PF01853.18 KKK14153.1 - 5.6e-75 250.9 0.0 9e-75 250.3 0.0 1.3 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 KKK14153.1 - 2.3e-21 75.1 3.8 5.1e-21 74.0 3.8 1.5 1 0 0 1 1 1 1 MYST family zinc finger domain PHD_4 PF16866.5 KKK14153.1 - 4.4e-12 45.9 7.0 1.3e-11 44.4 7.0 1.8 1 0 0 1 1 1 1 PHD-finger PHD PF00628.29 KKK14153.1 - 0.00015 21.6 8.7 0.00015 21.6 8.7 2.1 2 0 0 2 2 2 1 PHD-finger zf-MIZ PF02891.20 KKK14153.1 - 0.18 11.6 1.7 0.41 10.4 1.7 1.6 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-RING_9 PF13901.6 KKK14153.1 - 0.95 9.4 4.5 1.7 8.6 4.5 1.3 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon SNF2_N PF00176.23 KKK14154.1 - 6.3e-77 258.7 0.4 1.3e-76 257.7 0.4 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.10 KKK14154.1 - 6.8e-44 148.5 0.9 6.8e-44 148.5 0.9 2.1 2 0 0 2 2 1 1 SLIDE HAND PF09110.11 KKK14154.1 - 8.1e-38 129.6 1.3 8.1e-38 129.6 1.3 3.3 3 0 0 3 3 3 1 HAND Helicase_C PF00271.31 KKK14154.1 - 5.1e-18 65.4 0.7 3.9e-17 62.6 0.0 2.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KKK14154.1 - 3.1e-11 43.6 0.0 1.5e-10 41.3 0.0 2.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 KKK14154.1 - 6.1e-06 25.6 0.1 5e-05 22.6 0.0 2.4 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.29 KKK14154.1 - 0.00031 20.6 0.0 0.00081 19.2 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 KKK14154.1 - 0.00039 20.2 0.0 0.0012 18.6 0.0 1.8 1 0 0 1 1 1 1 SWI2/SNF2 ATPase AAA_14 PF13173.6 KKK14154.1 - 0.023 14.7 0.0 0.09 12.8 0.0 2.0 1 0 0 1 1 1 0 AAA domain DEAD_2 PF06733.15 KKK14154.1 - 0.063 12.9 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 DEAD_2 Tn7_Tnp_TnsA_C PF08721.11 KKK14154.1 - 0.12 13.0 0.4 0.57 10.9 0.1 2.3 2 0 0 2 2 2 0 TnsA endonuclease C terminal Occludin_ELL PF07303.13 KKK14154.1 - 0.17 12.6 4.0 0.68 10.7 4.0 2.0 1 0 0 1 1 1 0 Occludin homology domain DUF5618 PF18498.1 KKK14154.1 - 8.9 6.5 7.5 5.6 7.2 0.8 3.3 4 0 0 4 4 4 0 Domain of unknown function (DUF5618) FKBP_N PF01346.18 KKK14154.1 - 9.1 7.3 9.9 6.8 7.7 1.0 3.9 3 1 1 4 4 4 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase Acetyltransf_2 PF00797.17 KKK14155.1 - 1.2e-38 133.3 0.0 1.6e-38 132.8 0.0 1.2 1 0 0 1 1 1 1 N-acetyltransferase MWFE PF15879.5 KKK14156.1 - 1.2e-26 92.7 0.2 1.4e-26 92.4 0.2 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase MWFE subunit RraA-like PF03737.15 KKK14158.1 - 1.4e-27 96.7 0.1 1.9e-27 96.3 0.1 1.2 1 0 0 1 1 1 1 Aldolase/RraA Thiolase_N PF00108.23 KKK14159.1 - 1.8e-72 243.9 5.2 1.8e-72 243.9 5.2 1.5 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KKK14159.1 - 1.2e-43 147.7 0.2 2.9e-43 146.4 0.2 1.7 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KKK14159.1 - 0.0048 16.5 1.0 0.036 13.7 0.4 2.5 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain NUC173 PF08161.12 KKK14160.1 - 6.9e-83 277.3 0.3 1.1e-80 270.1 0.1 3.2 3 0 0 3 3 3 1 NUC173 domain Stork_head PF10264.9 KKK14160.1 - 0.0031 17.6 0.0 0.012 15.7 0.0 2.0 1 0 0 1 1 1 1 Winged helix Storkhead-box1 domain HEAT PF02985.22 KKK14160.1 - 0.014 15.6 0.8 4 7.9 0.0 3.6 3 0 0 3 3 3 0 HEAT repeat HEAT_2 PF13646.6 KKK14160.1 - 0.046 14.1 0.1 0.65 10.4 0.0 3.0 2 0 0 2 2 2 0 HEAT repeats DUF5071 PF16804.5 KKK14160.1 - 0.13 12.5 0.0 8.6 6.6 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5071) Cation_efflux PF01545.21 KKK14161.1 - 1.5e-13 50.9 12.1 2.1e-13 50.5 12.1 1.1 1 0 0 1 1 1 1 Cation efflux family zf-rbx1 PF12678.7 KKK14163.1 - 2.2e-08 34.3 2.4 5.6e-08 33.0 2.4 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 KKK14163.1 - 6.2e-08 32.9 8.1 1.2e-07 32.0 3.5 2.5 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 KKK14163.1 - 6.3e-07 29.2 0.6 1.1e-06 28.4 0.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KKK14163.1 - 2.6e-06 27.1 2.3 2.6e-06 27.1 2.3 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KKK14163.1 - 3.3e-06 26.9 2.8 9.5e-06 25.5 2.9 1.8 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KKK14163.1 - 3.8e-05 23.5 1.4 3.8e-05 23.5 1.4 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KKK14163.1 - 4.9e-05 23.1 0.6 4.9e-05 23.1 0.6 1.8 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 KKK14163.1 - 0.00064 19.7 6.0 0.0018 18.3 1.8 3.3 1 1 1 2 2 2 1 RING-type zinc-finger Zn_ribbon_17 PF17120.5 KKK14163.1 - 0.00096 18.7 1.6 0.004 16.7 0.6 2.2 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.5 KKK14163.1 - 0.0022 17.7 12.5 0.0055 16.4 0.8 3.6 4 0 0 4 4 4 2 RING-like zinc finger zf-ANAPC11 PF12861.7 KKK14163.1 - 0.0081 16.2 1.2 0.019 15.0 1.2 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger DUF2921 PF11145.8 KKK14163.1 - 0.04 11.8 0.9 0.063 11.1 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2921) PQ-loop PF04193.14 KKK14163.1 - 0.23 11.3 5.0 4.4 7.2 0.3 2.9 2 0 0 2 2 2 0 PQ loop repeat FANCL_C PF11793.8 KKK14163.1 - 2.6 8.3 5.6 12 6.1 5.6 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain DUF3671 PF12420.8 KKK14163.1 - 3.1 7.9 4.1 25 5.0 4.1 2.2 1 1 0 1 1 1 0 Protein of unknown function DUF3099 PF11298.8 KKK14163.1 - 6.7 6.9 8.5 0.73 10.0 0.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3099) COMPASS-Shg1 PF05205.12 KKK14164.1 - 2.1e-25 89.4 0.2 5e-25 88.2 0.2 1.7 1 0 0 1 1 1 1 COMPASS (Complex proteins associated with Set1p) component shg1 IF4E PF01652.18 KKK14165.1 - 4.5e-32 111.0 0.2 6.4e-32 110.5 0.2 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E GDA1_CD39 PF01150.17 KKK14166.1 - 4.6e-97 325.4 0.0 6e-97 325.0 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family DUF4598 PF15370.6 KKK14167.1 - 1.2e-28 99.8 6.6 1.2e-28 99.8 6.6 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF4598) GTP_EFTU PF00009.27 KKK14168.1 - 4.7e-57 192.7 0.1 6.7e-57 192.2 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 KKK14168.1 - 4.2e-19 68.9 0.0 9.6e-19 67.7 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 KKK14168.1 - 4.3e-17 62.3 2.1 9.9e-17 61.1 2.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KKK14168.1 - 1.3e-05 25.2 0.1 2.4e-05 24.4 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KKK14168.1 - 0.0013 18.6 0.2 0.0073 16.2 0.1 2.0 1 1 1 2 2 2 1 RsgA GTPase cobW PF02492.19 KKK14168.1 - 0.008 15.8 0.5 0.17 11.5 0.0 2.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.9 KKK14168.1 - 0.095 12.5 0.5 8.3 6.1 0.1 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation IF3_C PF00707.22 KKK14169.1 - 2.7e-09 36.9 1.3 4.4e-09 36.2 1.3 1.4 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain IF3_N PF05198.16 KKK14169.1 - 3.2e-08 33.7 0.1 1.6e-07 31.5 0.0 2.1 2 0 0 2 2 2 1 Translation initiation factor IF-3, N-terminal domain mIF3 PF14877.6 KKK14169.1 - 1.1e-06 28.5 1.6 6.8e-06 25.9 0.5 2.5 1 1 2 3 3 3 1 Mitochondrial translation initiation factor Cyclase PF04199.13 KKK14170.1 - 3.5e-09 37.0 0.0 3.7e-08 33.7 0.0 2.0 1 1 1 2 2 2 1 Putative cyclase DUF5490 PF17593.2 KKK14170.1 - 0.0017 18.3 0.2 0.0044 17.0 0.2 1.6 1 0 0 1 1 1 1 Family of unknown function (DUF5490) Cupin_3 PF05899.12 KKK14170.1 - 0.0059 16.3 0.0 0.01 15.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF861) RHD3 PF05879.12 KKK14171.1 - 0 1082.3 0.0 0 1082.0 0.0 1.0 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.19 KKK14171.1 - 7.3e-08 32.0 0.3 1.2e-07 31.2 0.3 1.2 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain Dynamin_N PF00350.23 KKK14171.1 - 7.8e-06 26.0 0.0 1.6e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 KKK14171.1 - 0.00011 22.3 0.0 0.00028 20.9 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_28 PF13521.6 KKK14171.1 - 0.0012 19.1 0.5 0.0033 17.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain Septin PF00735.18 KKK14171.1 - 0.17 11.2 0.1 0.29 10.4 0.1 1.4 1 0 0 1 1 1 0 Septin 4HBT_2 PF13279.6 KKK14172.1 - 2e-08 34.8 0.0 3.1e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily BRAP2 PF07576.12 KKK14191.1 - 3.3e-35 120.3 0.0 7.7e-35 119.1 0.0 1.5 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.19 KKK14191.1 - 5.5e-20 71.5 2.9 1.7e-19 69.9 2.9 1.9 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.6 KKK14191.1 - 4.6e-08 33.3 9.5 4.6e-08 33.3 9.5 2.5 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 KKK14191.1 - 1.5e-05 24.8 9.7 1.5e-05 24.8 9.7 2.1 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KKK14191.1 - 0.00068 19.9 7.1 0.00068 19.9 7.1 2.5 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 KKK14191.1 - 0.001 18.7 5.7 0.001 18.7 5.7 2.6 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4 PF00097.25 KKK14191.1 - 0.0012 18.7 8.8 0.0012 18.7 8.8 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KKK14191.1 - 0.0012 18.6 6.0 0.0012 18.6 6.0 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KKK14191.1 - 0.0017 18.3 6.3 0.0017 18.3 6.3 2.7 2 1 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 KKK14191.1 - 0.0022 17.9 7.9 0.0022 17.9 7.9 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_6 PF14835.6 KKK14191.1 - 0.0076 16.1 3.1 0.0076 16.1 3.1 2.0 2 0 0 2 2 1 1 zf-RING of BARD1-type protein ZapB PF06005.12 KKK14191.1 - 0.011 16.2 0.7 0.011 16.2 0.7 2.1 1 1 1 2 2 2 0 Cell division protein ZapB Shugoshin_N PF07558.11 KKK14191.1 - 0.021 14.7 1.2 0.045 13.6 1.2 1.5 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region AIP3 PF03915.13 KKK14191.1 - 0.03 13.4 3.8 0.049 12.7 3.8 1.2 1 0 0 1 1 1 0 Actin interacting protein 3 ALS2CR11 PF15729.5 KKK14191.1 - 0.037 13.2 0.9 0.091 11.9 0.9 1.6 1 1 0 1 1 1 0 Amyotrophic lateral sclerosis 2 candidate 11 TPR_MLP1_2 PF07926.12 KKK14191.1 - 0.66 10.0 12.9 1.4 9.0 12.9 1.5 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Prok-RING_4 PF14447.6 KKK14191.1 - 1.2 9.1 20.2 0.082 12.8 9.7 3.1 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 KKK14191.1 - 1.9 8.6 12.8 0.032 14.3 5.2 1.9 2 0 0 2 2 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-UBP_var PF17807.1 KKK14191.1 - 3.9 7.3 6.5 0.71 9.7 0.3 2.5 2 0 0 2 2 2 0 Variant UBP zinc finger Zn_clus PF00172.18 KKK14192.1 - 0.0033 17.5 7.7 0.007 16.5 7.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Prenyltrans PF00432.21 KKK14193.1 - 3e-31 106.8 40.2 4.3e-11 42.4 2.6 6.1 7 0 0 7 7 7 4 Prenyltransferase and squalene oxidase repeat dsrm PF00035.26 KKK14193.1 - 0.00066 20.3 0.0 0.0014 19.3 0.0 1.5 1 0 0 1 1 1 1 Double-stranded RNA binding motif DND1_DSRM PF14709.7 KKK14193.1 - 0.052 13.8 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 double strand RNA binding domain from DEAD END PROTEIN 1 MBOAT PF03062.19 KKK14194.1 - 2.5e-40 138.9 16.7 1.8e-31 109.8 5.5 2.5 2 0 0 2 2 2 2 MBOAT, membrane-bound O-acyltransferase family PufQ PF05398.11 KKK14194.1 - 0.057 13.5 4.2 0.6 10.3 0.1 2.7 2 1 0 2 2 2 0 PufQ cytochrome subunit Acylphosphatase PF00708.18 KKK14195.1 - 3.3e-19 69.1 0.1 4.7e-19 68.6 0.1 1.2 1 0 0 1 1 1 1 Acylphosphatase KAR9 PF08580.10 KKK14196.1 - 1.7e-211 704.4 31.7 2.8e-119 399.6 0.4 2.7 3 0 0 3 3 3 2 Yeast cortical protein KAR9 ATG16 PF08614.11 KKK14196.1 - 0.036 14.3 0.4 0.17 12.1 0.4 2.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Prefoldin_2 PF01920.20 KKK14196.1 - 0.5 10.3 1.6 3.3 7.7 0.0 3.0 3 0 0 3 3 3 0 Prefoldin subunit Acetyltransf_3 PF13302.7 KKK14197.1 - 0.001 19.8 0.0 0.0015 19.2 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KKK14197.1 - 0.0062 16.8 0.0 0.0086 16.3 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 KKK14197.1 - 0.074 13.2 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 KKK14197.1 - 0.18 11.8 0.0 0.34 10.9 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein AOX PF01786.17 KKK14198.1 - 2.5e-99 331.2 0.1 3.2e-99 330.9 0.1 1.1 1 0 0 1 1 1 1 Alternative oxidase Prefoldin PF02996.17 KKK14200.1 - 8.6e-30 103.1 0.2 1.2e-29 102.6 0.2 1.2 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.20 KKK14200.1 - 0.0011 18.9 0.1 0.0032 17.4 0.1 1.9 1 1 0 1 1 1 1 Prefoldin subunit FlaC_arch PF05377.11 KKK14200.1 - 0.06 13.7 0.2 3.2 8.2 0.0 2.4 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) RNA_polI_A34 PF08208.11 KKK14201.1 - 1.9e-43 149.0 12.7 1.9e-43 149.0 12.7 2.1 2 0 0 2 2 2 1 DNA-directed RNA polymerase I subunit RPA34.5 CLP1_P PF16575.5 KKK14202.1 - 5.6e-28 98.0 0.0 1.1e-27 97.1 0.0 1.5 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_33 PF13671.6 KKK14202.1 - 0.057 13.6 0.0 0.23 11.6 0.0 2.2 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KKK14202.1 - 0.086 13.4 0.0 0.24 12.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 KKK14202.1 - 0.13 11.6 0.0 0.42 9.9 0.0 1.8 2 0 0 2 2 2 0 FtsK/SpoIIIE family RNA_helicase PF00910.22 KKK14202.1 - 0.16 12.4 0.0 0.7 10.3 0.0 2.1 2 0 0 2 2 2 0 RNA helicase Folliculin PF11704.8 KKK14203.1 - 2.2e-49 167.9 0.0 2.8e-49 167.5 0.0 1.1 1 0 0 1 1 1 1 Vesicle coat protein involved in Golgi to plasma membrane transport GRAM PF02893.20 KKK14204.1 - 3.8e-35 120.2 3.3 4.1e-23 81.4 0.0 3.4 3 0 0 3 3 3 3 GRAM domain Glyco_transf_28 PF03033.20 KKK14204.1 - 1.2e-25 90.2 0.0 2.3e-25 89.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain PH PF00169.29 KKK14204.1 - 1.7e-15 57.4 0.5 1.9e-13 50.8 0.1 3.2 2 1 1 3 3 3 1 PH domain PH_3 PF14593.6 KKK14204.1 - 5.8e-05 23.2 0.0 0.00012 22.1 0.0 1.5 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 KKK14204.1 - 7.4e-05 23.1 0.6 0.00044 20.6 0.6 2.4 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 KKK14204.1 - 0.0001 22.5 0.1 0.00026 21.2 0.1 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain UDPGT PF00201.18 KKK14204.1 - 0.01 14.6 0.0 0.022 13.5 0.0 1.5 1 0 0 1 1 1 0 UDP-glucoronosyl and UDP-glucosyl transferase PH_2 PF08458.10 KKK14204.1 - 0.013 15.8 0.0 0.028 14.7 0.0 1.5 1 0 0 1 1 1 0 Plant pleckstrin homology-like region PITH PF06201.13 KKK14206.1 - 2.1e-37 128.7 0.0 3.2e-37 128.1 0.0 1.3 1 0 0 1 1 1 1 PITH domain Thioredoxin PF00085.20 KKK14206.1 - 1.6e-22 79.4 0.0 3.2e-22 78.5 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 KKK14206.1 - 1.8e-05 25.0 0.0 0.00089 19.5 0.0 2.5 1 1 1 2 2 2 2 Thioredoxin-like OST3_OST6 PF04756.13 KKK14206.1 - 4.2e-05 23.0 0.0 6.7e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 KKK14206.1 - 0.00093 19.6 0.2 0.0049 17.3 0.2 2.2 1 1 0 1 1 1 1 Thioredoxin-like domain Redoxin PF08534.10 KKK14206.1 - 0.0014 18.3 1.3 0.085 12.6 0.0 2.6 2 1 1 3 3 3 1 Redoxin Thioredoxin_9 PF14595.6 KKK14206.1 - 0.0021 17.8 0.0 0.004 16.9 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.21 KKK14206.1 - 0.0092 15.9 0.7 0.072 13.0 0.1 2.3 2 1 1 3 3 3 1 AhpC/TSA family HyaE PF07449.11 KKK14206.1 - 0.038 14.0 0.1 0.097 12.6 0.0 1.7 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE DSBA PF01323.20 KKK14206.1 - 0.072 12.9 0.2 0.16 11.7 0.1 1.6 1 1 1 2 2 2 0 DSBA-like thioredoxin domain Fructosamin_kin PF03881.14 KKK14208.1 - 0.027 13.7 0.0 0.041 13.1 0.0 1.2 1 0 0 1 1 1 0 Fructosamine kinase Forkhead PF00250.18 KKK14209.1 - 3.8e-36 123.2 1.4 6.8e-36 122.4 1.4 1.4 1 0 0 1 1 1 1 Forkhead domain FHA PF00498.26 KKK14209.1 - 6.6e-08 32.8 0.0 1.5e-07 31.7 0.0 1.6 1 0 0 1 1 1 1 FHA domain TENA_THI-4 PF03070.16 KKK14210.1 - 1.4e-11 44.7 0.0 6.3e-05 22.9 0.0 2.5 2 1 0 2 2 2 2 TENA/THI-4/PQQC family PLAC8 PF04749.17 KKK14211.1 - 8e-23 81.3 8.0 9.4e-23 81.1 8.0 1.1 1 0 0 1 1 1 1 PLAC8 family Methyltr_RsmB-F PF01189.17 KKK14212.1 - 9.1e-31 107.1 0.0 5.5e-24 84.9 0.0 2.8 2 1 0 2 2 2 2 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 KKK14212.1 - 0.099 12.7 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase UNC45-central PF11701.8 KKK14213.1 - 5.1e-39 133.7 2.0 1.5e-38 132.1 0.9 2.5 2 0 0 2 2 2 1 Myosin-binding striated muscle assembly central Arm PF00514.23 KKK14213.1 - 0.00011 22.1 15.5 5 7.3 0.1 8.0 8 0 0 8 8 8 2 Armadillo/beta-catenin-like repeat TPR_15 PF13429.6 KKK14213.1 - 0.0023 17.2 0.5 0.0051 16.1 0.1 1.7 2 0 0 2 2 2 1 Tetratricopeptide repeat Atx10homo_assoc PF09759.9 KKK14213.1 - 0.014 15.4 0.1 2.7 8.1 0.0 3.0 2 1 1 3 3 3 0 Spinocerebellar ataxia type 10 protein domain TPR_11 PF13414.6 KKK14213.1 - 0.035 13.8 0.0 0.074 12.7 0.0 1.5 1 0 0 1 1 1 0 TPR repeat TPR_16 PF13432.6 KKK14213.1 - 0.25 12.0 2.4 0.25 12.0 0.2 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat HEAT_2 PF13646.6 KKK14213.1 - 0.42 11.0 12.5 1.1 9.7 4.4 5.0 4 1 1 5 5 5 0 HEAT repeats TPR_14 PF13428.6 KKK14213.1 - 0.43 11.5 4.3 0.22 12.4 0.3 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat HEAT_EZ PF13513.6 KKK14213.1 - 3.2 8.4 12.0 32 5.2 0.4 5.2 5 0 0 5 5 5 0 HEAT-like repeat DUF4588 PF15251.6 KKK14214.1 - 0.96 9.2 8.1 1.4 8.6 8.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) zf-Tim10_DDP PF02953.15 KKK14215.1 - 5.7e-22 77.1 0.8 8e-22 76.7 0.8 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger PALB2_WD40 PF16756.5 KKK14215.1 - 0.036 13.0 0.5 0.046 12.7 0.5 1.1 1 0 0 1 1 1 0 Partner and localizer of BRCA2 WD40 domain Pkinase PF00069.25 KKK14216.1 - 2.4e-72 243.5 0.0 3.4e-72 243.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK14216.1 - 2.6e-36 125.3 0.0 4.2e-36 124.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KKK14216.1 - 6.5e-06 25.7 0.0 1.3e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like SPX PF03105.19 KKK14216.1 - 3.5 7.4 15.1 6.7 6.5 15.1 1.5 1 0 0 1 1 1 0 SPX domain Lectin_leg-like PF03388.13 KKK14217.1 - 3.7e-67 226.0 0.1 4.8e-67 225.7 0.1 1.1 1 0 0 1 1 1 1 Legume-like lectin family Lectin_legB PF00139.19 KKK14217.1 - 1.7e-05 24.5 0.1 0.0012 18.4 0.1 2.1 1 1 0 1 1 1 1 Legume lectin domain CRIM PF16978.5 KKK14218.1 - 1.8e-42 144.8 0.0 3e-42 144.1 0.0 1.4 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), middle CRIM domain SIN1_PH PF16979.5 KKK14218.1 - 1.6e-27 95.9 0.0 2.8e-27 95.2 0.0 1.4 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology PBP1_TM PF14812.6 KKK14218.1 - 0.006 16.9 9.1 0.033 14.6 6.4 2.7 2 0 0 2 2 2 1 Transmembrane domain of transglycosylase PBP1 at N-terminal PH PF00169.29 KKK14218.1 - 0.017 15.6 0.0 0.039 14.5 0.0 1.6 1 0 0 1 1 1 0 PH domain RFC1 PF08519.12 KKK14219.1 - 1.3e-61 207.4 0.0 3e-60 203.0 0.0 2.4 2 0 0 2 2 2 1 Replication factor RFC1 C terminal domain BRCT PF00533.26 KKK14219.1 - 1.9e-15 57.0 0.0 7.7e-15 55.0 0.0 2.2 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.29 KKK14219.1 - 1e-10 42.1 0.3 3.3e-10 40.5 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KKK14219.1 - 6.1e-06 26.6 0.0 1.5e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KKK14219.1 - 0.00022 21.6 0.1 0.0016 18.8 0.1 2.4 1 1 0 1 1 1 1 AAA ATPase domain Rad17 PF03215.15 KKK14219.1 - 0.0013 18.7 0.0 0.003 17.5 0.0 1.6 1 0 0 1 1 1 1 Rad17 P-loop domain DNA_pol3_delta PF06144.13 KKK14219.1 - 0.0021 17.9 0.0 0.0047 16.7 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_33 PF13671.6 KKK14219.1 - 0.0058 16.8 0.0 0.016 15.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 KKK14219.1 - 0.011 15.5 0.0 0.024 14.4 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Bac_DnaA PF00308.18 KKK14219.1 - 0.015 15.1 0.3 2 8.2 0.1 2.7 3 0 0 3 3 3 0 Bacterial dnaA protein AAA_5 PF07728.14 KKK14219.1 - 0.028 14.4 0.0 0.41 10.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 KKK14219.1 - 0.04 14.5 0.2 0.24 11.9 0.0 2.5 3 0 0 3 3 1 0 AAA domain Sigma54_activat PF00158.26 KKK14219.1 - 0.041 13.6 0.0 0.084 12.6 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain CMV_1a PF12467.8 KKK14219.1 - 0.064 13.6 1.1 0.66 10.3 0.2 2.7 2 0 0 2 2 2 0 Cucumber mosaic virus 1a protein family AAA_28 PF13521.6 KKK14219.1 - 0.11 12.8 0.4 0.55 10.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain Glyco_hydro_63 PF03200.16 KKK14220.1 - 2.2e-07 30.0 6.5 4e-05 22.6 0.2 4.0 4 1 0 4 4 4 2 Glycosyl hydrolase family 63 C-terminal domain SlyX PF04102.12 KKK14221.1 - 0.031 14.9 1.7 0.065 13.9 1.7 1.5 1 0 0 1 1 1 0 SlyX Neugrin PF06413.11 KKK14222.1 - 3.4e-14 53.4 0.3 3.4e-14 53.4 0.3 1.6 2 0 0 2 2 2 1 Neugrin MRP-L20 PF12824.7 KKK14222.1 - 2e-05 24.8 5.0 6e-05 23.3 5.0 1.8 1 1 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Rgp1 PF08737.10 KKK14223.1 - 8.2e-138 460.1 0.0 1.3e-137 459.4 0.0 1.3 1 0 0 1 1 1 1 Rgp1 Arrestin_N PF00339.29 KKK14223.1 - 1.4e-05 25.2 0.0 3.3e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 KKK14223.1 - 0.0083 16.6 0.0 0.17 12.3 0.0 3.0 3 0 0 3 3 3 1 Arrestin (or S-antigen), C-terminal domain Spo0M PF07070.11 KKK14223.1 - 0.13 11.7 0.0 0.27 10.7 0.0 1.4 1 0 0 1 1 1 0 SpoOM protein Mob1_phocein PF03637.17 KKK14224.1 - 1.3e-73 246.6 0.0 1.7e-73 246.2 0.0 1.1 1 0 0 1 1 1 1 Mob1/phocein family OSCP PF00213.18 KKK14225.1 - 6.1e-46 156.7 3.0 7.9e-46 156.3 3.0 1.1 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit WD40 PF00400.32 KKK14226.1 - 1.8e-15 57.0 12.2 0.017 16.0 0.1 8.5 11 0 0 11 11 11 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKK14226.1 - 0.0043 17.3 0.2 14 6.1 0.0 5.0 4 1 1 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain SPO22 PF08631.10 KKK14227.1 - 6.9e-23 81.5 9.6 1.6e-11 44.2 0.1 3.7 3 1 1 4 4 4 2 Meiosis protein SPO22/ZIP4 like TPR_8 PF13181.6 KKK14227.1 - 0.054 13.7 0.4 2.5 8.6 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat HLH PF00010.26 KKK14228.1 - 1e-06 28.6 0.0 2.2e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain ORC6 PF05460.13 KKK14228.1 - 1.7 7.8 9.9 3.3 6.9 9.9 1.4 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) CtaG_Cox11 PF04442.14 KKK14229.1 - 1e-58 197.6 0.0 1.7e-58 197.0 0.0 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 TMEM135_C_rich PF15982.5 KKK14229.1 - 0.00077 20.1 0.3 0.0021 18.7 0.3 1.7 1 1 0 1 1 1 1 N-terminal cysteine-rich region of Transmembrane protein 135 Cation_ATPase_C PF00689.21 KKK14229.1 - 0.0033 17.2 0.1 0.0082 15.9 0.0 1.6 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus CENP-Q PF13094.6 KKK14231.1 - 7.8e-44 149.8 7.0 1.5e-43 148.9 7.0 1.4 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit MCR_C PF04609.12 KKK14231.1 - 0.033 13.3 0.8 0.25 10.4 0.0 2.1 2 0 0 2 2 2 0 Methyl-coenzyme M reductase operon protein C Bep_C_terminal PF17841.1 KKK14231.1 - 0.034 14.4 0.4 2.5 8.4 0.0 2.8 2 1 0 2 2 2 0 BID domain of Bartonella effector protein (Bep) DDE_Tnp_4 PF13359.6 KKK14231.1 - 0.13 11.9 0.0 0.28 10.8 0.0 1.6 1 0 0 1 1 1 0 DDE superfamily endonuclease PRANC PF09372.10 KKK14231.1 - 0.14 12.5 0.4 0.78 10.1 0.0 2.2 2 0 0 2 2 2 0 PRANC domain DUF4337 PF14235.6 KKK14231.1 - 0.27 11.3 4.8 0.71 10.0 4.8 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) D5_N PF08706.11 KKK14231.1 - 0.7 10.1 2.9 3.1 8.1 2.9 2.0 1 1 0 1 1 1 0 D5 N terminal like zf-C4H2 PF10146.9 KKK14231.1 - 0.94 9.7 10.8 0.11 12.7 5.6 1.9 1 1 1 2 2 2 0 Zinc finger-containing protein SlyX PF04102.12 KKK14231.1 - 6.4 7.5 9.1 4.8 7.9 2.4 3.5 4 0 0 4 4 4 0 SlyX DNA_pol3_delta2 PF13177.6 KKK14232.1 - 1.2e-10 41.4 0.1 2.2e-10 40.6 0.1 1.5 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.29 KKK14232.1 - 8.8e-06 26.2 0.1 2.1e-05 25.0 0.1 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KKK14232.1 - 2.8e-05 24.4 0.3 0.00016 21.9 0.2 2.2 1 1 1 2 2 2 1 AAA domain Rep_fac_C PF08542.11 KKK14232.1 - 0.00028 21.3 0.1 0.001 19.4 0.0 2.0 2 0 0 2 2 2 1 Replication factor C C-terminal domain AAA_24 PF13479.6 KKK14232.1 - 0.0034 17.1 0.4 0.0085 15.8 0.4 1.6 1 1 0 1 1 1 1 AAA domain Rad17 PF03215.15 KKK14232.1 - 0.004 17.1 0.0 0.019 14.9 0.0 1.9 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_16 PF13191.6 KKK14232.1 - 0.0053 17.2 1.1 0.096 13.1 0.4 2.8 2 1 0 2 2 2 1 AAA ATPase domain ABC_tran PF00005.27 KKK14232.1 - 0.041 14.4 0.1 0.086 13.4 0.1 1.6 1 1 0 1 1 1 0 ABC transporter DNA_pol3_delta PF06144.13 KKK14232.1 - 0.049 13.4 0.1 0.095 12.5 0.1 1.4 1 0 0 1 1 1 0 DNA polymerase III, delta subunit Ribosomal_L16 PF00252.18 KKK14233.1 - 3.1e-32 111.3 0.1 3.9e-32 111.0 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Helo_like_N PF17111.5 KKK14234.1 - 0.0001 21.7 0.4 0.00052 19.4 0.0 2.3 2 0 0 2 2 2 1 Fungal N-terminal domain of STAND proteins PNP_UDP_1 PF01048.20 KKK14234.1 - 0.00081 18.7 0.0 0.0014 17.9 0.0 1.3 1 0 0 1 1 1 1 Phosphorylase superfamily Mg_trans_NIPA PF05653.14 KKK14235.1 - 1e-90 303.9 24.6 1.3e-90 303.5 24.6 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 KKK14235.1 - 2.3e-05 24.6 7.1 2.3e-05 24.6 7.1 3.3 3 0 0 3 3 3 1 EamA-like transporter family DUF805 PF05656.14 KKK14235.1 - 3.4 8.1 11.3 5.3 7.5 1.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF805) CcmE PF03100.15 KKK14237.1 - 0.19 11.7 1.4 0.31 11.0 0.0 1.9 2 0 0 2 2 2 0 CcmE Cation_ATPase_C PF00689.21 KKK14237.1 - 0.53 10.0 7.4 3 7.5 6.6 2.0 2 0 0 2 2 2 0 Cation transporting ATPase, C-terminus GATase PF00117.28 KKK14238.1 - 2.8e-38 131.6 0.0 4.8e-38 130.8 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GMP_synt_C PF00958.22 KKK14238.1 - 1.4e-36 124.4 0.0 2.9e-36 123.4 0.0 1.6 1 0 0 1 1 1 1 GMP synthase C terminal domain NAD_synthase PF02540.17 KKK14238.1 - 8.7e-10 38.1 0.0 2.6e-06 26.7 0.1 2.3 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.13 KKK14238.1 - 4.9e-05 23.2 0.1 0.00016 21.5 0.1 1.9 1 1 0 1 1 1 1 Peptidase C26 tRNA_Me_trans PF03054.16 KKK14238.1 - 0.00038 19.4 0.1 0.0012 17.7 0.1 1.7 2 0 0 2 2 2 1 tRNA methyl transferase ThiI PF02568.14 KKK14238.1 - 0.0032 17.1 0.0 0.0071 15.9 0.0 1.5 2 0 0 2 2 2 1 Thiamine biosynthesis protein (ThiI) QueC PF06508.13 KKK14238.1 - 0.0063 16.0 0.0 0.15 11.5 0.0 2.2 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC PAPS_reduct PF01507.19 KKK14238.1 - 0.0079 16.3 0.0 0.014 15.4 0.0 1.4 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family Arginosuc_synth PF00764.19 KKK14238.1 - 0.043 13.1 0.1 0.066 12.5 0.1 1.2 1 0 0 1 1 1 0 Arginosuccinate synthase LRR_4 PF12799.7 KKK14239.1 - 0.0011 19.3 6.6 0.17 12.3 0.1 4.6 4 0 0 4 4 4 1 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KKK14239.1 - 0.0048 16.8 0.0 0.01 15.7 0.0 1.6 1 0 0 1 1 1 1 F-box-like LRR_6 PF13516.6 KKK14239.1 - 0.021 14.8 3.7 36 4.8 0.2 4.6 4 0 0 4 4 4 0 Leucine Rich repeat F-box PF00646.33 KKK14239.1 - 0.031 14.2 1.5 0.24 11.3 1.0 2.7 2 1 0 2 2 2 0 F-box domain LURAP PF14854.6 KKK14239.1 - 0.09 12.7 0.4 0.21 11.5 0.4 1.6 1 0 0 1 1 1 0 Leucine rich adaptor protein LRR_8 PF13855.6 KKK14239.1 - 0.12 12.1 2.4 8.5 6.2 0.1 3.3 3 1 0 3 3 3 0 Leucine rich repeat LRR_1 PF00560.33 KKK14239.1 - 5.3 8.0 8.7 2.5e+02 2.9 0.0 5.7 5 1 0 5 5 5 0 Leucine Rich Repeat BSD PF03909.17 KKK14240.1 - 1.2e-28 98.9 10.8 6e-15 55.0 1.1 3.7 4 0 0 4 4 4 2 BSD domain PH_TFIIH PF08567.11 KKK14240.1 - 8.4e-25 86.9 0.0 2.2e-24 85.6 0.0 1.8 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain Rx_N PF18052.1 KKK14240.1 - 0.0059 16.9 0.5 0.025 14.8 0.2 2.2 2 0 0 2 2 2 1 Rx N-terminal domain PIN_8 PF18476.1 KKK14240.1 - 0.094 12.6 0.1 0.094 12.6 0.1 2.6 2 1 1 3 3 3 0 PIN like domain Pyr_redox_3 PF13738.6 KKK14240.1 - 0.14 11.4 0.1 2.5 7.2 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Mito_carr PF00153.27 KKK14241.1 - 3e-63 209.8 2.8 1.2e-21 76.5 0.0 4.2 4 0 0 4 4 4 4 Mitochondrial carrier protein Serine_protease PF18405.1 KKK14241.1 - 0.032 13.4 0.0 2.1 7.5 0.0 2.6 2 0 0 2 2 2 0 Gammaproteobacterial serine protease RsfS PF02410.15 KKK14242.1 - 6.9e-12 45.7 0.0 1.4e-11 44.6 0.0 1.6 1 0 0 1 1 1 1 Ribosomal silencing factor during starvation WAC_Acf1_DNA_bd PF10537.9 KKK14243.1 - 2e-39 134.2 1.3 2e-39 134.2 1.3 2.7 3 0 0 3 3 3 1 ATP-utilising chromatin assembly and remodelling N-terminal WSD PF15613.6 KKK14243.1 - 5.6e-22 78.1 0.7 5.6e-22 78.1 0.7 3.6 3 0 0 3 3 3 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif DDT PF02791.17 KKK14243.1 - 5.8e-17 61.7 1.5 1.1e-16 60.8 1.5 1.5 1 0 0 1 1 1 1 DDT domain WHIM1 PF15612.6 KKK14243.1 - 8.8e-10 37.9 0.1 2.3e-09 36.5 0.1 1.8 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 Pex2_Pex12 PF04757.14 KKK14244.1 - 1.2e-55 188.5 2.1 1.6e-55 188.1 2.1 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_4 PF15227.6 KKK14244.1 - 2.2e-05 24.5 3.4 4e-05 23.7 3.4 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 KKK14244.1 - 0.003 17.8 2.2 0.0058 16.9 2.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KKK14244.1 - 0.0044 17.0 3.5 0.0044 17.0 3.5 1.8 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KKK14244.1 - 0.0075 16.1 3.4 0.0098 15.7 2.1 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KKK14244.1 - 0.013 15.3 1.9 0.022 14.6 1.9 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KKK14244.1 - 0.024 14.5 2.4 0.042 13.7 2.4 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Auto_anti-p27 PF06677.12 KKK14244.1 - 2.9 8.1 4.1 5.1 7.3 4.1 1.4 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) TPR_2 PF07719.17 KKK14246.1 - 4.6e-07 29.5 0.0 0.0036 17.3 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 KKK14246.1 - 1.3e-06 28.7 0.3 0.014 16.2 0.2 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 KKK14246.1 - 3.2e-06 27.5 0.6 6.9e-06 26.5 0.3 1.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 KKK14246.1 - 4.7e-06 26.8 0.0 1.4e-05 25.3 0.0 1.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 KKK14246.1 - 1.5e-05 25.5 0.1 2.9e-05 24.6 0.1 1.5 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.6 KKK14246.1 - 2.4e-05 24.2 0.0 0.015 15.5 0.0 3.0 4 0 0 4 4 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 KKK14246.1 - 4.1e-05 23.2 0.2 0.019 14.8 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_15 PF13429.6 KKK14246.1 - 0.00053 19.3 0.1 0.006 15.8 0.1 2.0 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 KKK14246.1 - 0.0024 17.7 0.0 2.7 8.0 0.0 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 KKK14246.1 - 0.0025 18.3 0.0 0.083 13.6 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_MalT PF17874.1 KKK14246.1 - 0.0031 16.9 0.1 0.0045 16.4 0.1 1.2 1 0 0 1 1 1 1 MalT-like TPR region ANAPC3 PF12895.7 KKK14246.1 - 0.019 15.2 0.0 0.036 14.3 0.0 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 KKK14246.1 - 0.02 14.6 0.0 0.059 13.1 0.0 1.8 2 0 0 2 2 2 0 TPR repeat TPR_9 PF13371.6 KKK14246.1 - 0.037 14.2 0.1 4 7.7 0.1 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_4 PF07721.14 KKK14246.1 - 0.068 13.8 0.4 0.42 11.4 0.5 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 KKK14246.1 - 0.07 13.6 0.0 0.11 12.9 0.0 1.4 1 0 0 1 1 1 0 Alkyl sulfatase dimerisation ChAPs PF09295.10 KKK14246.1 - 0.096 11.7 0.0 0.15 11.0 0.0 1.3 1 0 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_7 PF13176.6 KKK14246.1 - 0.11 12.6 0.0 28 5.1 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat SIR2 PF02146.17 KKK14247.1 - 1.1e-59 201.3 0.0 1.6e-59 200.8 0.0 1.3 1 0 0 1 1 1 1 Sir2 family UPF0020 PF01170.18 KKK14247.1 - 2.3e-07 30.7 0.1 0.0031 17.2 0.1 2.4 1 1 1 2 2 2 2 Putative RNA methylase family UPF0020 DUF592 PF04574.13 KKK14247.1 - 0.00067 19.4 0.0 0.0013 18.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF592) TPP_enzyme_M PF00205.22 KKK14247.1 - 0.029 14.1 0.1 4.7 7.0 0.0 2.4 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain HIT PF01230.23 KKK14248.1 - 6.6e-13 49.2 1.5 3.5e-12 46.9 1.5 2.0 1 1 0 1 1 1 1 HIT domain CwfJ_C_1 PF04677.15 KKK14248.1 - 0.0087 15.9 0.3 0.024 14.5 0.0 1.8 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 1 DcpS_C PF11969.8 KKK14248.1 - 0.013 16.0 1.8 0.18 12.3 1.8 2.1 1 1 0 1 1 1 0 Scavenger mRNA decapping enzyme C-term binding RWD PF05773.22 KKK14249.1 - 3.8e-25 88.4 2.3 3.8e-25 88.4 2.3 1.6 2 0 0 2 2 2 1 RWD domain DFRP_C PF16543.5 KKK14249.1 - 0.15 12.6 16.5 0.45 11.0 14.8 2.5 1 1 1 2 2 2 0 DRG Family Regulatory Proteins, Tma46 ORC3_N PF07034.11 KKK14249.1 - 0.35 9.9 3.3 0.48 9.5 3.3 1.1 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 3 N-terminus Complex1_LYR PF05347.15 KKK14250.1 - 5.6e-15 55.1 1.7 7.7e-15 54.7 0.0 2.1 2 1 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KKK14250.1 - 3.2e-05 24.6 2.5 6e-05 23.7 1.2 2.2 2 1 0 2 2 2 1 Complex1_LYR-like Complex1_LYR_1 PF13232.6 KKK14250.1 - 0.031 14.9 0.4 0.1 13.2 0.0 2.0 2 0 0 2 2 2 0 Complex1_LYR-like WD40 PF00400.32 KKK14251.1 - 2.5e-19 69.3 12.9 4.4e-07 30.5 0.1 6.2 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKK14251.1 - 9e-17 61.2 0.0 0.00024 21.4 0.0 4.6 2 2 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain PALB2_WD40 PF16756.5 KKK14251.1 - 0.00095 18.2 0.0 0.0016 17.5 0.0 1.3 1 0 0 1 1 1 1 Partner and localizer of BRCA2 WD40 domain Nup160 PF11715.8 KKK14251.1 - 0.0026 16.5 0.3 0.41 9.2 0.1 2.1 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 KKK14251.1 - 0.015 13.8 0.0 0.31 9.5 0.1 2.1 2 0 0 2 2 2 0 Cytochrome D1 heme domain eIF2A PF08662.11 KKK14251.1 - 0.022 14.6 0.1 1.3 8.9 0.0 2.8 2 1 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A Fungal_trans PF04082.18 KKK14252.1 - 7.6e-20 71.1 0.0 1.4e-19 70.2 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK14252.1 - 1.3e-09 38.0 12.0 2.6e-09 37.1 12.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF655 PF04919.12 KKK14252.1 - 0.16 11.9 0.0 0.27 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF655) Ribosomal_L2_C PF03947.18 KKK14253.1 - 1e-51 174.4 1.9 1.5e-50 170.6 1.8 2.4 2 1 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 KKK14253.1 - 2.7e-25 88.1 0.9 1e-24 86.2 0.3 2.3 3 0 0 3 3 3 1 Ribosomal Proteins L2, RNA binding domain PAS PF00989.25 KKK14253.1 - 0.15 12.1 0.1 0.29 11.1 0.1 1.4 1 0 0 1 1 1 0 PAS fold Cyclin_N PF00134.23 KKK14254.1 - 4.7e-45 152.4 0.1 2e-44 150.4 0.1 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KKK14254.1 - 7.7e-34 116.3 0.0 1.7e-33 115.2 0.0 1.6 1 0 0 1 1 1 1 Cyclin, C-terminal domain Dna2 PF08696.11 KKK14255.1 - 8.4e-68 228.2 1.0 1.7e-67 227.2 1.0 1.5 1 0 0 1 1 1 1 DNA replication factor Dna2 AAA_12 PF13087.6 KKK14255.1 - 3.8e-53 180.1 0.0 6.5e-53 179.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KKK14255.1 - 2.2e-31 109.6 6.3 1.4e-17 64.4 0.0 3.4 3 1 1 4 4 4 2 AAA domain AAA_30 PF13604.6 KKK14255.1 - 9e-15 54.9 0.0 1.6e-14 54.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KKK14255.1 - 7e-13 49.1 0.4 1.9e-12 47.7 0.2 1.9 2 0 0 2 2 1 1 AAA domain Cas_Cas4 PF01930.17 KKK14255.1 - 6e-08 33.0 0.1 2e-07 31.3 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function DUF83 PDDEXK_1 PF12705.7 KKK14255.1 - 2.9e-07 30.7 0.0 7.9e-07 29.2 0.0 1.8 1 1 0 1 1 1 1 PD-(D/E)XK nuclease superfamily Viral_helicase1 PF01443.18 KKK14255.1 - 4.1e-07 30.0 0.1 0.43 10.3 0.0 3.6 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.14 KKK14255.1 - 8.4e-05 22.5 0.0 0.00025 21.0 0.0 1.9 1 0 0 1 1 1 1 Helicase UvrD-helicase PF00580.21 KKK14255.1 - 0.00074 19.1 1.8 0.0015 18.2 0.1 2.2 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain SRP54 PF00448.22 KKK14255.1 - 0.0017 18.0 0.1 0.0035 17.0 0.1 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_16 PF13191.6 KKK14255.1 - 0.0033 17.8 0.0 0.0096 16.3 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain PIF1 PF05970.14 KKK14255.1 - 0.0085 15.3 0.2 0.24 10.5 0.0 2.4 3 0 0 3 3 3 1 PIF1-like helicase CbiA PF01656.23 KKK14255.1 - 0.0089 16.1 0.2 0.03 14.4 0.2 1.8 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MobB PF03205.14 KKK14255.1 - 0.01 15.7 0.1 0.024 14.5 0.1 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ResIII PF04851.15 KKK14255.1 - 0.01 15.8 0.0 0.028 14.4 0.0 1.7 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_7 PF12775.7 KKK14255.1 - 0.049 13.1 0.1 0.1 12.1 0.1 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF87 PF01935.17 KKK14255.1 - 0.059 13.4 0.2 0.18 11.9 0.2 1.8 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_18 PF13238.6 KKK14255.1 - 0.069 13.7 0.0 0.6 10.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 KKK14255.1 - 0.1 13.0 0.2 0.36 11.3 0.0 2.1 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KKK14255.1 - 0.11 12.5 0.0 0.39 10.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) MeaB PF03308.16 KKK14255.1 - 0.13 11.2 0.1 0.31 10.0 0.1 1.5 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_25 PF13481.6 KKK14255.1 - 0.15 11.7 0.0 0.34 10.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 KKK14255.1 - 0.18 11.7 0.2 0.6 10.0 0.2 1.8 1 0 0 1 1 1 0 NTPase Ribonuc_P_40 PF08584.11 KKK14256.1 - 1.5e-70 237.7 0.0 1.9e-70 237.4 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease P 40kDa (Rpp40) subunit CN_hydrolase PF00795.22 KKK14257.1 - 3.9e-33 114.9 0.0 4.8e-33 114.6 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Clathrin_propel PF01394.20 KKK14257.1 - 0.092 13.1 0.1 17 5.9 0.0 2.4 2 0 0 2 2 2 0 Clathrin propeller repeat ESSS PF10183.9 KKK14258.1 - 1.1e-18 67.4 0.0 1.2e-18 67.3 0.0 1.1 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) RNB PF00773.19 KKK14259.1 - 3.5e-98 328.9 0.4 6.9e-98 328.0 0.1 1.6 2 0 0 2 2 2 1 RNB domain Rrp44_CSD1 PF17216.3 KKK14259.1 - 7.5e-31 106.8 0.0 1.7e-30 105.7 0.0 1.6 1 0 0 1 1 1 1 Rrp44-like cold shock domain Rrp44_S1 PF17215.3 KKK14259.1 - 5e-28 96.9 1.3 1.1e-27 95.7 1.3 1.6 1 0 0 1 1 1 1 S1 domain OB_Dis3 PF17849.1 KKK14259.1 - 6.6e-20 70.9 0.0 1.6e-19 69.7 0.0 1.7 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) PIN_4 PF13638.6 KKK14259.1 - 5e-09 36.5 0.3 1.1e-08 35.4 0.3 1.6 1 0 0 1 1 1 1 PIN domain CSD2 PF17876.1 KKK14259.1 - 1.3e-08 34.9 0.4 2.3e-05 24.4 0.0 3.2 2 1 1 3 3 3 2 Cold shock domain Gti1_Pac2 PF09729.9 KKK14260.1 - 1.5e-46 158.8 1.0 7.3e-39 133.7 0.1 2.1 1 1 1 2 2 2 2 Gti1/Pac2 family NucS PF01939.16 KKK14260.1 - 0.15 11.4 0.0 0.21 10.9 0.0 1.1 1 0 0 1 1 1 0 Endonuclease NucS Peptidase_C54 PF03416.19 KKK14269.1 - 1.9e-96 322.7 0.0 2.2e-96 322.5 0.0 1.0 1 0 0 1 1 1 1 Peptidase family C54 Histone PF00125.24 KKK14270.1 - 6.9e-17 62.0 0.0 9.1e-17 61.7 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KKK14270.1 - 9.2e-06 25.9 0.0 1.3e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone_H2A_C PF16211.5 KKK14270.1 - 4.7e-05 23.0 3.1 0.003 17.2 0.1 2.4 2 0 0 2 2 2 2 C-terminus of histone H2A Histone PF00125.24 KKK14271.1 - 1.4e-21 77.2 0.5 1.7e-21 76.9 0.5 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KKK14271.1 - 0.0004 20.6 0.0 0.0004 20.6 0.0 1.7 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 KKK14271.1 - 0.00049 20.5 0.0 0.00082 19.8 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A RP-C PF03428.13 KKK14271.1 - 0.052 13.2 0.1 0.12 12.0 0.1 1.5 1 1 0 1 1 1 0 Replication protein C N-terminal domain YscO-like PF16789.5 KKK14271.1 - 0.064 13.3 0.1 0.074 13.1 0.1 1.1 1 0 0 1 1 1 0 YscO-like protein 2-oxoacid_dh PF00198.23 KKK14272.1 - 2e-80 269.6 0.1 3.7e-80 268.7 0.0 1.4 2 0 0 2 2 2 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 KKK14272.1 - 8.9e-19 67.1 1.8 1.7e-18 66.2 1.8 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 KKK14272.1 - 0.00014 21.6 0.2 0.0056 16.5 0.1 2.4 1 1 1 2 2 2 1 Biotin-lipoyl like HlyD_3 PF13437.6 KKK14272.1 - 0.00095 19.8 0.1 0.23 12.2 0.0 2.5 1 1 1 2 2 2 1 HlyD family secretion protein RnfC_N PF13375.6 KKK14272.1 - 0.0077 16.2 0.2 0.057 13.4 0.0 2.2 1 1 1 2 2 2 1 RnfC Barrel sandwich hybrid domain HlyD_D23 PF16576.5 KKK14272.1 - 0.0078 15.5 0.2 2.2 7.4 0.0 2.4 1 1 1 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion GCV_H PF01597.19 KKK14272.1 - 0.016 15.1 0.4 0.033 14.1 0.4 1.5 1 0 0 1 1 1 0 Glycine cleavage H-protein Ndc1_Nup PF09531.10 KKK14272.1 - 1.5 7.4 3.2 1.9 7.1 3.2 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup FAP PF07174.11 KKK14272.1 - 3.3 7.1 14.9 5.1 6.5 14.9 1.2 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) MSA-2c PF12238.8 KKK14272.1 - 5.8 6.9 7.9 11 6.0 7.9 1.5 1 0 0 1 1 1 0 Merozoite surface antigen 2c Complex1_LYR PF05347.15 KKK14273.1 - 2.7e-10 40.1 0.3 3.8e-10 39.7 0.3 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) DnaJ PF00226.31 KKK14274.1 - 7.5e-23 80.4 4.1 1.3e-22 79.6 2.2 2.5 2 0 0 2 2 2 1 DnaJ domain TPR_1 PF00515.28 KKK14274.1 - 3.5e-14 51.9 0.3 2.7e-06 26.9 0.0 6.5 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_2 PF07719.17 KKK14274.1 - 1.1e-13 50.2 0.8 0.00069 19.5 0.0 7.1 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_9 PF13371.6 KKK14274.1 - 1.5e-12 47.4 3.8 5.1e-06 26.5 0.8 4.6 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 KKK14274.1 - 1.2e-10 41.8 3.7 7.2e-06 26.4 0.1 4.2 4 1 1 5 5 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 KKK14274.1 - 3.6e-10 39.8 7.5 0.022 15.5 0.6 6.2 3 3 4 7 7 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 KKK14274.1 - 6.5e-09 35.3 0.9 0.16 12.2 0.0 7.1 8 0 0 8 8 7 1 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 KKK14274.1 - 9.7e-07 28.5 1.5 0.0026 17.4 0.1 2.6 2 0 0 2 2 2 2 Bacterial type III secretion protein (HrpB1_HrpK) TPR_16 PF13432.6 KKK14274.1 - 1.7e-06 28.6 11.0 0.019 15.6 0.0 4.8 6 0 0 6 6 4 2 Tetratricopeptide repeat PknG_TPR PF16918.5 KKK14274.1 - 0.00019 20.3 0.1 0.027 13.2 0.0 2.8 2 1 1 3 3 3 1 Protein kinase G tetratricopeptide repeat TPR_6 PF13174.6 KKK14274.1 - 0.0002 21.8 11.1 4.6 8.1 0.0 7.6 9 0 0 9 9 7 1 Tetratricopeptide repeat TPR_7 PF13176.6 KKK14274.1 - 0.00042 20.1 0.7 1.3 9.2 0.0 4.6 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 KKK14274.1 - 0.00056 20.2 1.0 7.5 6.9 0.0 4.4 4 1 0 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KKK14274.1 - 0.0013 18.9 9.2 0.01 16.1 0.1 4.8 3 2 2 6 6 6 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 KKK14274.1 - 0.0028 17.3 2.5 0.03 14.0 0.0 4.1 6 1 0 6 6 6 1 TPR repeat TPR_17 PF13431.6 KKK14274.1 - 0.0089 16.3 5.2 0.3 11.6 0.0 4.2 5 0 0 5 5 3 1 Tetratricopeptide repeat PNMA PF14893.6 KKK14274.1 - 2 7.7 8.0 5 6.4 1.1 2.6 1 1 2 3 3 3 0 PNMA PCMT PF01135.19 KKK14275.1 - 6.9e-55 186.0 0.0 2.1e-54 184.5 0.0 1.6 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 KKK14275.1 - 7.7e-09 35.5 0.0 9.9e-09 35.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKK14275.1 - 9.2e-07 29.5 0.0 1.6e-06 28.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 KKK14275.1 - 4.2e-05 23.6 0.0 6.2e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KKK14275.1 - 6.5e-05 22.8 0.0 9.2e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KKK14275.1 - 0.00065 20.3 0.0 0.0011 19.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KKK14275.1 - 0.0033 18.1 0.0 0.0052 17.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 KKK14275.1 - 0.0067 16.0 0.0 0.0095 15.5 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW MTS PF05175.14 KKK14275.1 - 0.021 14.4 0.0 0.037 13.6 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase small domain PrmA PF06325.13 KKK14275.1 - 0.037 13.4 0.0 0.051 13.0 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.18 KKK14275.1 - 0.051 12.9 0.0 0.072 12.4 0.0 1.1 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family FtsJ PF01728.19 KKK14275.1 - 0.08 13.0 0.0 0.11 12.6 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase GCD14 PF08704.10 KKK14275.1 - 0.091 12.4 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit RrnaAD PF00398.20 KKK14275.1 - 0.21 10.6 0.0 0.27 10.2 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Bestrophin PF01062.21 KKK14276.1 - 9.1e-33 113.9 0.0 1.3e-32 113.4 0.0 1.1 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel FHA PF00498.26 KKK14276.1 - 3.6e-13 49.6 0.0 7e-13 48.7 0.0 1.5 1 0 0 1 1 1 1 FHA domain zf-RING_11 PF17123.5 KKK14276.1 - 6.1e-10 38.7 3.6 1.4e-09 37.6 3.6 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 KKK14276.1 - 1.8e-06 28.1 8.5 4.3e-06 26.9 8.5 1.7 1 0 0 1 1 1 1 Ring finger domain Yop-YscD_cpl PF16697.5 KKK14276.1 - 0.0003 21.1 0.0 0.00061 20.1 0.0 1.4 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain zf-RING_5 PF14634.6 KKK14276.1 - 0.0018 18.2 6.3 0.0035 17.3 6.3 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING-like PF08746.11 KKK14276.1 - 0.028 14.7 5.4 0.071 13.4 5.4 1.7 1 0 0 1 1 1 0 RING-like domain zf-ANAPC11 PF12861.7 KKK14276.1 - 0.086 12.9 2.8 0.18 11.9 2.8 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.6 KKK14276.1 - 0.19 11.6 8.9 0.44 10.4 8.9 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PHD PF00628.29 KKK14276.1 - 0.3 11.0 5.8 0.55 10.2 5.8 1.4 1 0 0 1 1 1 0 PHD-finger zf-C3HC4 PF00097.25 KKK14276.1 - 0.38 10.7 9.5 0.34 10.8 7.6 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KKK14276.1 - 0.73 10.2 8.7 1.9 8.8 8.7 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-H2C2_2 PF13465.6 KKK14276.1 - 3 8.4 4.2 1.2 9.7 0.7 2.2 2 0 0 2 2 1 0 Zinc-finger double domain zf-C3HC4_4 PF15227.6 KKK14276.1 - 4.1 7.6 6.5 8.3 6.7 6.0 1.9 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING MS_channel PF00924.18 KKK14277.1 - 5e-23 81.7 2.0 5e-23 81.7 2.0 1.8 2 0 0 2 2 2 1 Mechanosensitive ion channel EF-hand_5 PF13202.6 KKK14277.1 - 0.00023 20.5 0.1 0.00055 19.3 0.1 1.7 1 0 0 1 1 1 1 EF hand EF-hand_1 PF00036.32 KKK14277.1 - 0.00062 19.1 0.4 0.0016 17.9 0.4 1.7 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 KKK14277.1 - 0.0014 18.4 0.0 0.0036 17.1 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 KKK14277.1 - 0.014 15.9 0.3 0.036 14.5 0.3 1.6 1 0 0 1 1 1 0 EF-hand domain pair DUF3384 PF11864.8 KKK14281.1 - 1.3e-99 334.3 2.3 1.3e-99 334.3 2.3 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3384) Rap_GAP PF02145.15 KKK14281.1 - 8e-51 172.2 0.0 1.4e-50 171.4 0.0 1.4 1 0 0 1 1 1 1 Rap/ran-GAP Tuberin PF03542.16 KKK14281.1 - 1.9e-37 129.2 0.0 2.1e-32 112.6 0.0 3.2 3 0 0 3 3 3 2 Tuberin RTP1_C1 PF10363.9 KKK14281.1 - 0.006 16.7 0.0 0.57 10.4 0.0 3.3 3 0 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 CAS_CSE1 PF03378.15 KKK14282.1 - 3.2e-193 642.2 0.7 6.7e-193 641.2 0.0 1.9 3 0 0 3 3 3 1 CAS/CSE protein, C-terminus Cse1 PF08506.10 KKK14282.1 - 1.4e-159 530.9 1.6 1.9e-159 530.4 1.6 1.2 1 0 0 1 1 1 1 Cse1 IBN_N PF03810.19 KKK14282.1 - 3.3e-16 59.0 0.3 1e-15 57.4 0.3 2.0 1 0 0 1 1 1 1 Importin-beta N-terminal domain Xpo1 PF08389.12 KKK14282.1 - 0.0032 17.5 3.3 0.035 14.2 0.1 4.1 5 0 0 5 5 5 1 Exportin 1-like protein DUF4083 PF13314.6 KKK14283.1 - 0.018 15.0 0.7 0.029 14.3 0.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) DUF5326 PF17260.2 KKK14283.1 - 0.041 14.0 0.4 0.071 13.3 0.4 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5326) DUF3377 PF11857.8 KKK14283.1 - 0.11 12.4 0.4 0.44 10.5 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) Phosphodiest PF01663.22 KKK14284.1 - 2.9e-15 56.7 0.1 5.2e-15 55.9 0.1 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 KKK14284.1 - 3.3e-05 23.4 0.1 6.4e-05 22.4 0.1 1.4 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.23 KKK14284.1 - 0.00022 20.7 0.1 0.00038 19.9 0.1 1.4 1 0 0 1 1 1 1 Sulfatase PglZ PF08665.12 KKK14284.1 - 0.071 13.2 0.4 14 5.7 0.1 2.3 2 0 0 2 2 2 0 PglZ domain Gly-zipper_YMGG PF13441.6 KKK14284.1 - 0.58 9.9 4.6 1.3 8.8 4.6 1.5 1 0 0 1 1 1 0 YMGG-like Gly-zipper DUF1640 PF07798.11 KKK14285.1 - 1.9e-36 125.8 4.3 2.5e-36 125.3 4.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) HIP1_clath_bdg PF16515.5 KKK14285.1 - 0.097 13.3 4.5 0.13 12.8 2.6 2.1 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Vps51 PF08700.11 KKK14286.1 - 1.5e-15 57.0 0.0 2e-14 53.4 0.0 2.8 2 0 0 2 2 2 1 Vps51/Vps67 Apolipoprotein PF01442.18 KKK14286.1 - 0.017 15.0 8.4 2.1 8.2 0.1 3.8 3 1 0 3 3 3 0 Apolipoprotein A1/A4/E domain GlutR_dimer PF00745.20 KKK14286.1 - 0.25 11.8 1.9 12 6.4 0.1 3.9 4 0 0 4 4 4 0 Glutamyl-tRNAGlu reductase, dimerisation domain COG2 PF06148.11 KKK14286.1 - 0.82 9.8 3.3 5.7 7.0 0.0 3.8 6 0 0 6 6 6 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF883 PF05957.13 KKK14286.1 - 1 10.0 4.6 7.3 7.3 0.1 3.4 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) D123 PF07065.14 KKK14287.1 - 3.7e-113 377.7 0.1 5.4e-113 377.2 0.1 1.2 1 0 0 1 1 1 1 D123 ECH_1 PF00378.20 KKK14288.1 - 1.3e-26 93.4 0.0 1.8e-26 93.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KKK14288.1 - 3.8e-20 72.7 0.0 4.2e-20 72.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Pet100 PF09803.9 KKK14289.1 - 1.1e-18 67.5 0.1 1.4e-18 67.2 0.1 1.1 1 0 0 1 1 1 1 Pet100 SPT_ssu-like PF11779.8 KKK14290.1 - 1.7e-25 88.4 2.7 1.7e-25 88.4 2.7 1.6 2 0 0 2 2 2 1 Small subunit of serine palmitoyltransferase-like RF-1 PF00472.20 KKK14291.1 - 3.6e-24 84.9 4.4 4.9e-24 84.5 4.4 1.2 1 0 0 1 1 1 1 RF-1 domain B56 PF01603.20 KKK14295.1 - 3.9e-191 635.5 7.2 4.7e-191 635.2 7.2 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Sec7_N PF12783.7 KKK14295.1 - 0.0008 19.3 2.5 0.44 10.5 0.1 2.5 2 0 0 2 2 2 2 Guanine nucleotide exchange factor in Golgi transport N-terminal RAC_head PF16717.5 KKK14295.1 - 4.7 8.2 6.2 50 4.9 0.1 3.2 3 0 0 3 3 3 0 Ribosome-associated complex head domain TPR_2 PF07719.17 KKK14296.1 - 2.2e-05 24.2 3.3 1.5 9.1 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KKK14296.1 - 7.5e-05 22.4 0.7 3.3 7.7 0.2 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.6 KKK14296.1 - 0.0017 18.2 1.2 1.2 9.3 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 KKK14296.1 - 0.0037 17.8 0.6 0.062 13.8 0.0 2.8 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 KKK14296.1 - 0.014 15.6 9.9 0.41 11.0 0.5 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 KKK14296.1 - 2.4 8.2 8.1 18 5.4 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 KKK14296.1 - 2.5 8.8 18.5 1.1 9.9 0.6 3.5 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 KKK14296.1 - 3.5 8.7 11.8 5.8 8.0 0.0 3.8 1 1 3 4 4 4 0 Tetratricopeptide repeat MARVEL PF01284.23 KKK14326.1 - 0.0015 18.6 0.1 0.0023 18.0 0.1 1.2 1 0 0 1 1 1 1 Membrane-associating domain PHD PF00628.29 KKK14328.1 - 2.7e-09 36.8 2.6 6.1e-09 35.6 2.6 1.6 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 KKK14328.1 - 0.0043 16.6 3.3 0.0069 15.9 3.3 1.3 1 0 0 1 1 1 1 PHD-finger UIM PF02809.20 KKK14328.1 - 0.028 14.3 2.4 0.028 14.3 2.4 2.4 2 0 0 2 2 2 0 Ubiquitin interaction motif zf-CW PF07496.15 KKK14328.1 - 0.23 11.5 1.6 0.59 10.2 1.6 1.7 1 0 0 1 1 1 0 CW-type Zinc Finger eIF-5a PF01287.20 KKK14329.1 - 1.3e-05 25.2 0.0 2.9e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold Fungal_trans PF04082.18 KKK14330.1 - 7.7e-17 61.2 0.2 1.1e-16 60.7 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain ABC2_membrane PF01061.24 KKK14331.1 - 5.2e-79 264.5 60.2 1.2e-41 142.5 19.4 3.5 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.27 KKK14331.1 - 3.4e-37 128.0 0.1 1.8e-17 64.1 0.0 2.6 3 0 0 3 3 2 2 ABC transporter PDR_CDR PF06422.12 KKK14331.1 - 4.5e-34 116.2 11.9 7.4e-33 112.3 0.3 4.0 3 0 0 3 3 3 1 CDR ABC transporter ABC_trans_N PF14510.6 KKK14331.1 - 1e-16 61.3 0.0 2.5e-16 60.1 0.0 1.7 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_25 PF13481.6 KKK14331.1 - 1.2e-06 28.2 0.1 3.9e-05 23.3 0.0 2.6 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 KKK14331.1 - 1.6e-06 28.6 0.5 0.0013 19.2 0.2 2.4 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 KKK14331.1 - 3.7e-06 27.0 0.1 0.0027 17.6 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 KKK14331.1 - 0.00033 20.3 1.8 0.026 14.2 0.2 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_18 PF13238.6 KKK14331.1 - 0.0016 19.0 0.0 0.056 14.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KKK14331.1 - 0.0033 17.4 0.7 2.5 8.0 0.1 2.7 2 0 0 2 2 2 2 NACHT domain AAA_21 PF13304.6 KKK14331.1 - 0.0035 17.2 1.1 2.9 7.6 0.1 3.0 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 KKK14331.1 - 0.0056 17.0 1.6 1.6 9.0 0.4 2.7 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KKK14331.1 - 0.0081 16.3 1.9 0.022 14.9 0.1 2.3 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KKK14331.1 - 0.011 15.5 0.3 2.4 7.8 0.1 2.3 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.19 KKK14331.1 - 0.015 14.7 0.0 2.6 7.4 0.0 3.3 3 1 0 3 3 3 0 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 KKK14331.1 - 0.041 14.0 0.1 6.9 6.8 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_17 PF13207.6 KKK14331.1 - 0.056 13.9 0.4 6.2 7.3 0.0 2.6 2 1 0 2 2 2 0 AAA domain cobW PF02492.19 KKK14331.1 - 0.059 12.9 1.0 1.5 8.4 0.1 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain IstB_IS21 PF01695.17 KKK14331.1 - 0.095 12.4 0.2 1.4 8.6 0.0 2.6 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA PF00004.29 KKK14331.1 - 0.17 12.3 0.1 31 5.0 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PDR_assoc PF08370.11 KKK14331.1 - 0.57 10.0 4.8 0.19 11.5 0.4 2.5 2 0 0 2 2 2 0 Plant PDR ABC transporter associated PMT PF02366.18 KKK14332.1 - 2e-80 269.9 16.5 4.7e-80 268.7 16.5 1.6 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 KKK14332.1 - 8.1e-67 224.7 10.4 8.1e-67 224.7 10.4 2.6 3 0 0 3 3 3 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 KKK14332.1 - 1.3e-46 158.9 0.0 2.1e-46 158.1 0.0 1.3 1 0 0 1 1 1 1 MIR domain PRP21_like_P PF12230.8 KKK14333.1 - 3.5e-58 197.0 10.2 3.5e-58 197.0 10.2 1.8 2 0 0 2 2 2 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.20 KKK14333.1 - 1.5e-37 127.3 7.4 6.6e-20 70.9 0.1 2.9 3 0 0 3 3 3 2 Surp module zf_UBZ PF18439.1 KKK14333.1 - 0.0078 15.8 0.2 0.018 14.6 0.2 1.7 1 0 0 1 1 1 1 Ubiquitin-Binding Zinc Finger B12D PF06522.11 KKK14334.1 - 0.095 12.5 0.1 0.2 11.5 0.1 1.6 1 1 0 1 1 1 0 NADH-ubiquinone reductase complex 1 MLRQ subunit RHH_5 PF07878.11 KKK14334.1 - 0.15 12.0 0.2 0.29 11.0 0.0 1.5 2 0 0 2 2 2 0 CopG-like RHH_1 or ribbon-helix-helix domain, RHH_5 DUF1616 PF07760.11 KKK14334.1 - 0.16 11.4 0.0 0.2 11.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1616) dsDNA_bind PF01984.20 KKK14335.1 - 5.3e-38 129.7 15.9 6.2e-38 129.5 15.9 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain cwf18 PF08315.12 KKK14335.1 - 0.012 16.3 4.7 0.014 16.1 4.7 1.1 1 0 0 1 1 1 0 cwf18 pre-mRNA splicing factor DUF4615 PF15393.6 KKK14335.1 - 0.015 15.9 0.7 0.015 15.9 0.7 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4615) CdiI_N PF18228.1 KKK14335.1 - 0.071 12.9 0.0 0.1 12.5 0.0 1.2 1 0 0 1 1 1 0 CdiI N-terminal domain AAA_18 PF13238.6 KKK14335.1 - 0.083 13.4 0.9 0.11 13.0 0.4 1.5 1 1 0 1 1 1 0 AAA domain Sec2p PF06428.11 KKK14336.1 - 2.1e-28 98.1 14.2 2.1e-28 98.1 14.2 2.3 2 1 0 2 2 2 1 GDP/GTP exchange factor Sec2p Macoilin PF09726.9 KKK14336.1 - 6.1e-05 21.8 5.2 6.1e-05 21.8 5.2 1.7 2 0 0 2 2 2 1 Macoilin family DUF3584 PF12128.8 KKK14336.1 - 0.00074 17.2 16.6 0.0011 16.7 16.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) TetR_C_1 PF02909.17 KKK14336.1 - 0.095 12.5 0.1 24 4.7 0.0 2.7 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Mer2 PF09074.10 KKK14336.1 - 0.23 11.2 9.7 0.46 10.3 9.7 1.4 1 0 0 1 1 1 0 Mer2 GCN5L1 PF06320.13 KKK14336.1 - 0.38 10.9 14.5 1 9.6 8.1 2.5 2 0 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) DUF1759 PF03564.15 KKK14336.1 - 0.42 10.5 4.4 0.41 10.6 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1759) Exonuc_VII_L PF02601.15 KKK14336.1 - 1.1 8.8 8.8 2.2 7.8 8.8 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit KxDL PF10241.9 KKK14336.1 - 1.3 9.3 7.8 10 6.5 1.2 2.5 2 0 0 2 2 2 0 Uncharacterized conserved protein KfrA_N PF11740.8 KKK14336.1 - 2.2 9.0 17.2 1.7 9.4 0.2 2.7 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term DUF1515 PF07439.11 KKK14336.1 - 3.5 7.7 4.6 14 5.8 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) YjbH PF06082.11 KKK14336.1 - 4.5 6.0 10.9 0.062 12.1 3.8 1.4 2 0 0 2 2 2 0 Exopolysaccharide biosynthesis protein YbjH Golgin_A5 PF09787.9 KKK14336.1 - 5.6 6.3 23.6 0.082 12.4 16.3 1.6 2 0 0 2 2 2 0 Golgin subfamily A member 5 Phage_HK97_TLTM PF06120.11 KKK14336.1 - 6.3 5.9 15.4 34 3.5 15.5 1.9 1 1 0 1 1 1 0 Tail length tape measure protein SET PF00856.28 KKK14337.1 - 5e-19 69.3 0.0 8.1e-19 68.6 0.0 1.3 1 0 0 1 1 1 1 SET domain CDC73_C PF05179.14 KKK14337.1 - 0.073 12.8 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 RNA pol II accessory factor, Cdc73 family, C-terminal Coq4 PF05019.13 KKK14338.1 - 2.7e-98 327.7 0.0 3.2e-98 327.5 0.0 1.0 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 Sas10_Utp3 PF04000.15 KKK14339.1 - 1.3e-17 64.2 0.6 1.3e-17 64.2 0.6 2.0 2 1 0 2 2 2 1 Sas10/Utp3/C1D family CHCH PF06747.13 KKK14339.1 - 0.00018 21.5 1.8 0.00038 20.5 1.8 1.6 1 0 0 1 1 1 1 CHCH domain DUF2076 PF09849.9 KKK14339.1 - 0.00062 19.9 28.0 0.0016 18.6 25.9 2.1 1 1 1 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2076) Hid1 PF12722.7 KKK14339.1 - 0.0041 15.3 5.6 0.0053 15.0 5.6 1.1 1 0 0 1 1 1 1 High-temperature-induced dauer-formation protein CDC45 PF02724.14 KKK14339.1 - 0.016 13.5 0.6 0.019 13.3 0.6 1.1 1 0 0 1 1 1 0 CDC45-like protein CX9C PF16860.5 KKK14339.1 - 0.051 13.6 0.7 0.095 12.7 0.7 1.4 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Zip PF02535.22 KKK14339.1 - 0.21 10.8 1.7 0.27 10.4 1.7 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Presenilin PF01080.17 KKK14339.1 - 0.92 8.2 5.1 1.2 7.9 5.1 1.1 1 0 0 1 1 1 0 Presenilin PI3K_1B_p101 PF10486.9 KKK14339.1 - 1.6 6.4 6.7 2.2 5.9 6.7 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Suf PF05843.14 KKK14339.1 - 2.4 8.1 8.2 3.5 7.5 8.2 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Use1 PF09753.9 KKK14339.1 - 2.5 7.8 9.3 3.9 7.1 9.3 1.3 1 0 0 1 1 1 0 Membrane fusion protein Use1 ApbA_C PF08546.11 KKK14340.1 - 1.8e-34 118.6 0.1 3e-34 117.9 0.1 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 KKK14340.1 - 3.6e-26 91.6 0.0 1.4e-24 86.4 0.0 2.2 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA SURF1 PF02104.15 KKK14341.1 - 9e-48 162.8 0.0 1.3e-47 162.3 0.0 1.2 1 0 0 1 1 1 1 SURF1 family UBX PF00789.20 KKK14342.1 - 2e-09 37.5 0.0 4.1e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 UBX domain CMS1 PF14617.6 KKK14343.1 - 8.9e-57 192.3 8.4 2.2e-56 191.0 8.1 1.8 1 1 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.29 KKK14343.1 - 6.9e-06 25.9 0.0 7.7e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Dicty_REP PF05086.12 KKK14343.1 - 0.25 9.3 2.0 0.3 9.0 2.0 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein H-K_ATPase_N PF09040.11 KKK14343.1 - 0.58 10.6 7.1 15 6.1 3.0 3.1 3 0 0 3 3 3 0 Gastric H+/K+-ATPase, N terminal domain CENP-T_C PF15511.6 KKK14344.1 - 3.4e-45 152.6 0.1 5.1e-45 152.0 0.1 1.3 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 KKK14344.1 - 7.5e-09 35.9 0.1 1.3e-08 35.1 0.1 1.4 1 0 0 1 1 1 1 CENP-S protein Histone PF00125.24 KKK14344.1 - 0.00026 21.4 0.0 0.00055 20.3 0.0 1.6 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 DUF531 PF04407.12 KKK14344.1 - 0.043 13.9 0.0 0.067 13.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF531) CBFD_NFYB_HMF PF00808.23 KKK14344.1 - 0.11 12.8 0.0 0.18 12.1 0.0 1.4 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Aldedh PF00171.22 KKK14352.1 - 7.7e-98 328.0 0.1 1e-97 327.6 0.1 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Cys_Met_Meta_PP PF01053.20 KKK14354.1 - 1.2e-11 43.8 0.1 1.5e-11 43.5 0.1 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme TauD PF02668.16 KKK14355.1 - 4.8e-43 147.9 0.2 1.8e-36 126.3 0.0 2.1 1 1 1 2 2 2 2 Taurine catabolism dioxygenase TauD, TfdA family UPF0302 PF08864.10 KKK14355.1 - 0.0095 16.0 0.0 0.019 15.0 0.0 1.5 1 0 0 1 1 1 1 UPF0302 domain Asp_protease PF09668.10 KKK14356.1 - 1.3e-61 205.9 0.1 2e-61 205.3 0.1 1.3 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 KKK14356.1 - 2.1e-22 79.5 0.0 6.2e-22 78.0 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KKK14356.1 - 1.8e-10 41.3 0.0 4.9e-10 39.9 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease ubiquitin PF00240.23 KKK14356.1 - 4.8e-09 35.8 0.0 8.9e-09 35.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.31 KKK14356.1 - 2e-05 24.4 0.0 5.4e-05 23.0 0.0 1.8 1 0 0 1 1 1 1 UBA/TS-N domain RVP_2 PF08284.11 KKK14356.1 - 0.0022 17.7 0.0 0.0045 16.8 0.0 1.5 1 1 0 1 1 1 1 Retroviral aspartyl protease RVP PF00077.20 KKK14356.1 - 0.0045 17.3 0.0 0.015 15.6 0.0 1.9 1 0 0 1 1 1 1 Retroviral aspartyl protease UBA_4 PF14555.6 KKK14356.1 - 0.012 15.4 0.0 0.03 14.2 0.0 1.6 1 0 0 1 1 1 0 UBA-like domain Rad60-SLD PF11976.8 KKK14356.1 - 0.016 15.1 0.0 0.03 14.1 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like NAD_binding_7 PF13241.6 KKK14356.1 - 0.038 14.4 0.1 0.71 10.3 0.0 2.3 2 0 0 2 2 2 0 Putative NAD(P)-binding Ubiquitin_4 PF18036.1 KKK14356.1 - 0.049 13.7 0.0 0.65 10.1 0.0 2.4 2 0 0 2 2 2 0 Ubiquitin-like domain DUF2781 PF10914.8 KKK14357.1 - 2.4e-40 138.3 8.0 2.7e-40 138.1 8.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) Peptidase_S10 PF00450.22 KKK14367.1 - 1.3e-116 390.5 0.0 1.6e-116 390.2 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Myc_target_1 PF15179.6 KKK14367.1 - 0.2 11.5 0.1 0.36 10.7 0.1 1.3 1 0 0 1 1 1 0 Myc target protein 1 Stevor PF17410.2 KKK14367.1 - 0.24 10.9 0.1 0.58 9.7 0.0 1.6 2 0 0 2 2 2 0 Subtelomeric Variable Open Reading frame RNA_Me_trans PF04252.13 KKK14369.1 - 2.4e-83 278.6 0.0 2.7e-83 278.5 0.0 1.0 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase bPH_5 PF10882.8 KKK14369.1 - 0.0074 16.3 0.0 5.3 7.2 0.0 2.2 2 0 0 2 2 2 2 Bacterial PH domain FAD_binding_2 PF00890.24 KKK14370.1 - 1.2e-124 416.6 3.4 1.8e-124 416.1 3.4 1.3 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 KKK14370.1 - 1.4e-44 151.1 1.6 2.1e-44 150.6 1.6 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.14 KKK14370.1 - 7.3e-06 25.4 0.2 0.0011 18.3 0.1 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KKK14370.1 - 2.6e-05 23.5 1.3 0.044 12.9 2.7 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A Thi4 PF01946.17 KKK14370.1 - 7.2e-05 22.1 0.2 0.045 13.0 0.1 2.3 2 0 0 2 2 2 2 Thi4 family FAD_binding_3 PF01494.19 KKK14370.1 - 0.0028 17.0 0.8 0.0075 15.6 0.2 2.0 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 KKK14370.1 - 0.0055 16.3 0.8 0.016 14.9 0.8 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KKK14370.1 - 0.19 10.4 1.0 0.73 8.5 0.5 2.2 3 0 0 3 3 3 0 HI0933-like protein AAA PF00004.29 KKK14371.1 - 3e-40 137.7 0.0 5.3e-40 136.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KKK14371.1 - 8.7e-06 25.4 0.1 2e-05 24.3 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 KKK14371.1 - 0.00012 22.1 0.1 0.00062 19.8 0.0 2.2 3 1 0 3 3 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KKK14371.1 - 0.00015 22.1 0.0 0.0055 17.0 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 KKK14371.1 - 0.00049 20.5 0.1 0.011 16.1 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_2 PF07724.14 KKK14371.1 - 0.00052 20.2 0.0 0.0016 18.6 0.0 1.7 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 KKK14371.1 - 0.0014 17.8 0.0 0.0026 17.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 KKK14371.1 - 0.0093 15.7 0.0 0.018 14.8 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 KKK14371.1 - 0.019 15.2 0.1 0.063 13.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KKK14371.1 - 0.03 13.8 0.0 0.095 12.2 0.0 1.8 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 KKK14371.1 - 0.046 13.9 0.0 0.095 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KKK14371.1 - 0.063 13.7 0.0 0.15 12.4 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_3 PF07726.11 KKK14371.1 - 0.088 12.7 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 KKK14371.1 - 0.094 12.4 0.0 0.28 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KKK14371.1 - 0.11 12.3 0.1 0.59 9.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 KKK14371.1 - 0.11 12.5 0.0 0.25 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KKK14371.1 - 0.14 12.7 0.0 0.5 10.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain p450 PF00067.22 KKK14372.1 - 2.6e-23 82.5 0.0 2.9e-23 82.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 PARP PF00644.20 KKK14373.1 - 3.7e-61 206.1 0.0 3.7e-61 206.1 0.0 1.7 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.14 KKK14373.1 - 5.8e-42 143.0 0.0 9.7e-42 142.3 0.0 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.15 KKK14373.1 - 4.4e-24 84.4 0.9 9.3e-24 83.3 0.9 1.6 1 0 0 1 1 1 1 WGR domain PTCB-BRCT PF12738.7 KKK14373.1 - 1.9e-07 30.9 0.4 4.3e-07 29.8 0.4 1.6 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.26 KKK14373.1 - 3.3e-07 30.6 0.3 8.5e-07 29.3 0.3 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 KKK14373.1 - 0.0021 18.4 0.4 0.0049 17.2 0.4 1.6 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain Cpn60_TCP1 PF00118.24 KKK14374.1 - 1.7e-149 498.6 13.4 1.9e-149 498.4 13.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family zf-C2H2 PF00096.26 KKK14375.1 - 0.00025 21.3 3.8 0.00025 21.3 3.8 3.4 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 KKK14375.1 - 0.0063 16.2 2.7 0.0063 16.2 2.7 2.7 2 0 0 2 2 2 1 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.6 KKK14375.1 - 0.014 16.2 3.1 0.014 16.2 3.1 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger C1_4 PF07975.12 KKK14375.1 - 0.17 12.1 0.2 0.17 12.1 0.2 2.2 3 0 0 3 3 3 0 TFIIH C1-like domain MSA-2c PF12238.8 KKK14375.1 - 0.18 11.8 2.5 0.36 10.8 2.5 1.5 1 0 0 1 1 1 0 Merozoite surface antigen 2c zf-H2C2_2 PF13465.6 KKK14375.1 - 0.92 10.1 19.2 0.63 10.6 4.7 3.7 3 0 0 3 3 3 0 Zinc-finger double domain MFS_1 PF07690.16 KKK14427.1 - 2.4e-22 79.4 52.5 1.1e-17 64.0 39.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily PSI_8 PF00796.18 KKK14427.1 - 0.074 12.9 0.6 0.41 10.5 0.6 2.3 1 0 0 1 1 1 0 Photosystem I reaction centre subunit VIII Glyco_transf_20 PF00982.21 KKK14428.1 - 1.6e-149 498.6 0.0 2.1e-149 498.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 KKK14428.1 - 1.2e-82 276.6 0.0 1.6e-82 276.1 0.0 1.2 1 0 0 1 1 1 1 Trehalose-phosphatase Hydrolase_3 PF08282.12 KKK14428.1 - 0.0019 18.0 0.0 0.36 10.5 0.0 2.2 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase PP28 PF10252.9 KKK14429.1 - 4e-30 104.1 8.3 4e-30 104.1 8.3 3.0 2 2 1 3 3 3 1 Casein kinase substrate phosphoprotein PP28 DNA_pol_phi PF04931.13 KKK14429.1 - 3.3 5.7 12.9 5.4 5.0 12.9 1.3 1 0 0 1 1 1 0 DNA polymerase phi Cyto_heme_lyase PF01265.17 KKK14430.1 - 6.7e-131 436.2 1.2 7.6e-131 436.0 1.2 1.0 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase ABC1 PF03109.16 KKK14431.1 - 1.6e-21 76.7 0.0 6e-12 45.8 0.0 2.7 3 0 0 3 3 3 2 ABC1 family Raf1_HTH PF18579.1 KKK14431.1 - 0.0027 17.4 0.0 0.0062 16.2 0.0 1.6 1 0 0 1 1 1 1 Rubisco accumulation factor 1 helix turn helix domain RIO1 PF01163.22 KKK14431.1 - 0.018 14.7 0.0 0.33 10.5 0.0 2.3 2 0 0 2 2 2 0 RIO1 family Bac_surface_Ag PF01103.23 KKK14432.1 - 5.2e-41 141.2 0.2 6.6e-41 140.9 0.2 1.1 1 0 0 1 1 1 1 Surface antigen AAA PF00004.29 KKK14433.1 - 2e-43 148.0 0.0 3.4e-43 147.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KKK14433.1 - 5e-14 51.8 0.0 1e-13 50.9 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 KKK14433.1 - 6.7e-08 32.6 0.0 1.6e-07 31.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KKK14433.1 - 1.2e-07 32.0 0.0 2.4e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 KKK14433.1 - 1.3e-06 28.9 0.0 8.8e-05 23.0 0.0 2.8 2 1 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 KKK14433.1 - 2.3e-05 24.7 0.3 0.0081 16.4 0.0 2.4 1 1 1 2 2 2 1 AAA domain Prot_ATP_ID_OB PF16450.5 KKK14433.1 - 2.7e-05 24.0 2.2 6.5e-05 22.8 2.2 1.7 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain RuvB_N PF05496.12 KKK14433.1 - 0.0001 22.1 0.0 0.0002 21.1 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 KKK14433.1 - 0.00023 21.7 0.0 0.016 15.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.13 KKK14433.1 - 0.0012 18.1 0.0 0.0026 17.0 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 KKK14433.1 - 0.0015 18.7 0.0 0.0031 17.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KKK14433.1 - 0.0025 17.5 0.0 0.0046 16.7 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 KKK14433.1 - 0.0047 16.3 0.1 0.018 14.4 0.1 1.9 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 KKK14433.1 - 0.0053 16.6 0.0 0.015 15.2 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 KKK14433.1 - 0.0063 15.9 0.0 0.02 14.3 0.0 1.8 2 0 0 2 2 1 1 KaiC AAA_28 PF13521.6 KKK14433.1 - 0.011 16.0 0.0 0.019 15.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 KKK14433.1 - 0.015 15.3 0.0 0.029 14.4 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF815 PF05673.13 KKK14433.1 - 0.023 13.9 0.0 0.041 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Sigma54_activat PF00158.26 KKK14433.1 - 0.025 14.3 0.1 0.11 12.2 0.0 2.1 2 1 0 2 2 2 0 Sigma-54 interaction domain AAA_24 PF13479.6 KKK14433.1 - 0.027 14.2 0.0 0.066 12.9 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KKK14433.1 - 0.032 13.8 0.0 0.058 12.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region PhoH PF02562.16 KKK14433.1 - 0.033 13.7 0.0 0.14 11.6 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein HR1 PF02185.16 KKK14433.1 - 0.037 14.2 0.8 0.095 12.8 0.8 1.7 1 0 0 1 1 1 0 Hr1 repeat RNA_helicase PF00910.22 KKK14433.1 - 0.04 14.3 0.0 0.079 13.4 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_14 PF13173.6 KKK14433.1 - 0.046 13.8 0.0 0.079 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 KKK14433.1 - 0.052 13.9 0.0 0.62 10.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 KKK14433.1 - 0.059 12.9 0.1 0.16 11.5 0.0 1.7 2 0 0 2 2 1 0 AAA domain Parvo_NS1 PF01057.17 KKK14433.1 - 0.061 12.4 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DUF2072 PF09845.9 KKK14433.1 - 0.061 13.6 0.1 0.13 12.5 0.1 1.5 1 0 0 1 1 1 0 Zn-ribbon containing protein Zeta_toxin PF06414.12 KKK14433.1 - 0.097 11.9 0.0 0.17 11.1 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Prot_ATP_OB_N PF17758.1 KKK14433.1 - 0.11 12.2 0.3 0.42 10.3 0.1 2.1 2 0 0 2 2 1 0 Proteasomal ATPase OB N-terminal domain NOG1 PF06858.14 KKK14434.1 - 0.063 13.1 0.1 0.19 11.5 0.1 1.9 1 0 0 1 1 1 0 Nucleolar GTP-binding protein 1 (NOG1) Imm50 PF15594.6 KKK14434.1 - 0.074 13.3 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 Immunity protein 50 UQ_con PF00179.26 KKK14435.1 - 6.1e-20 71.3 0.1 8.8e-20 70.8 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RibD_C PF01872.17 KKK14436.1 - 1.4e-20 74.0 0.0 5.7e-20 72.0 0.0 1.9 1 1 0 1 1 1 1 RibD C-terminal domain Pex14_N PF04695.13 KKK14436.1 - 0.11 13.2 9.5 0.23 12.1 9.5 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Lin-8 PF03353.15 KKK14436.1 - 2.3 7.7 5.1 3.4 7.1 5.1 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist F-box PF00646.33 KKK14438.1 - 0.02 14.7 0.0 0.052 13.4 0.0 1.6 1 0 0 1 1 1 0 F-box domain DUF1497 PF07384.11 KKK14438.1 - 0.25 11.8 1.1 0.51 10.8 1.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1497) Y_phosphatase PF00102.27 KKK14439.1 - 8.9e-61 205.4 0.0 8.9e-61 205.4 0.0 2.8 2 1 0 2 2 1 1 Protein-tyrosine phosphatase Rhodanese PF00581.20 KKK14439.1 - 1.7e-10 41.4 0.0 2.3e-09 37.7 0.0 2.6 2 0 0 2 2 2 1 Rhodanese-like domain TFIIA PF03153.13 KKK14439.1 - 0.0023 18.0 2.8 0.0023 18.0 2.8 1.6 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit DSPc PF00782.20 KKK14439.1 - 0.0034 17.2 1.5 0.0036 17.1 0.0 1.8 2 0 0 2 2 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 KKK14439.1 - 0.012 15.6 1.1 0.02 14.9 0.0 1.9 2 0 0 2 2 2 0 Tyrosine phosphatase family Activator_LAG-3 PF11498.8 KKK14439.1 - 0.033 13.2 14.6 0.056 12.4 14.6 1.3 1 0 0 1 1 1 0 Transcriptional activator LAG-3 DDE_Tnp_IS240 PF13610.6 KKK14439.1 - 0.033 14.4 0.0 0.063 13.5 0.0 1.4 1 0 0 1 1 1 0 DDE domain Spt20 PF12090.8 KKK14439.1 - 0.042 13.5 10.2 0.083 12.5 10.2 1.4 1 0 0 1 1 1 0 Spt20 family SUIM_assoc PF16619.5 KKK14439.1 - 0.065 13.3 11.2 0.19 11.8 11.2 1.8 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Hydin_ADK PF17213.3 KKK14439.1 - 0.11 12.8 0.1 0.4 10.9 0.2 1.9 3 0 0 3 3 2 0 Hydin Adenylate kinase-like domain ECH_1 PF00378.20 KKK14439.1 - 0.13 11.5 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase Roughex PF06020.11 KKK14439.1 - 0.35 9.9 2.3 0.55 9.3 2.3 1.2 1 0 0 1 1 1 0 Drosophila roughex protein DUF4834 PF16118.5 KKK14439.1 - 0.65 11.0 2.6 1.8 9.5 2.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) NYN_YacP PF05991.11 KKK14439.1 - 5.4 6.9 6.0 22 5.0 0.0 2.4 1 1 1 2 2 2 0 YacP-like NYN domain COX16 PF14138.6 KKK14440.1 - 1.9e-31 108.4 0.2 2.5e-31 108.0 0.2 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 DPM3 PF08285.11 KKK14441.1 - 1.5e-32 111.6 0.1 1.1e-29 102.5 0.0 2.0 2 0 0 2 2 2 2 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Nic96 PF04097.14 KKK14442.1 - 1.1e-217 724.4 0.0 1.5e-217 724.0 0.0 1.0 1 0 0 1 1 1 1 Nup93/Nic96 Nucleoporin_FG PF13634.6 KKK14442.1 - 7.7e-05 23.5 20.5 7.7e-05 23.5 20.5 2.9 3 0 0 3 3 3 1 Nucleoporin FG repeat region Na_Ca_ex PF01699.24 KKK14443.1 - 2.6e-20 72.9 35.4 1.6e-14 54.1 14.1 4.6 5 1 0 5 5 5 2 Sodium/calcium exchanger protein YccF PF03733.13 KKK14443.1 - 8e-15 55.3 11.1 8e-15 55.3 11.1 4.5 5 0 0 5 5 5 1 Inner membrane component domain NOA36 PF06524.12 KKK14443.1 - 0.32 10.3 18.0 0.1 11.9 13.7 1.9 2 0 0 2 2 2 0 NOA36 protein GCIP PF13324.6 KKK14443.1 - 0.53 9.9 3.6 1.1 8.8 3.6 1.5 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Nop14 PF04147.12 KKK14443.1 - 2.3 6.3 10.7 3.3 5.8 10.7 1.1 1 0 0 1 1 1 0 Nop14-like family Cwf_Cwc_15 PF04889.12 KKK14443.1 - 2.6 7.7 14.1 4.8 6.8 14.1 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DNA_pol_phi PF04931.13 KKK14443.1 - 2.6 6.1 14.9 3.8 5.5 14.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi Tom22 PF04281.13 KKK14443.1 - 3.1 7.6 3.8 8.4 6.2 3.8 1.7 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 SDA1 PF05285.12 KKK14443.1 - 5.1 6.4 8.8 8.1 5.8 8.8 1.2 1 0 0 1 1 1 0 SDA1 FGGY_C PF02782.16 KKK14444.1 - 5.2e-50 169.9 0.1 8.8e-50 169.2 0.1 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 KKK14444.1 - 1.9e-23 83.3 0.1 1.6e-22 80.3 0.1 2.1 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.20 KKK14444.1 - 0.01 15.3 0.0 0.032 13.7 0.0 1.8 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family DEDD_Tnp_IS110 PF01548.17 KKK14444.1 - 0.09 12.7 0.8 1 9.2 0.2 2.4 2 0 0 2 2 2 0 Transposase UFD1 PF03152.14 KKK14445.1 - 3.2e-26 91.9 0.0 3.5e-16 59.2 0.0 3.3 3 0 0 3 3 3 3 Ubiquitin fusion degradation protein UFD1 AZUL PF16558.5 KKK14445.1 - 8.1e-08 32.4 0.4 2.9e-07 30.6 0.4 2.0 1 0 0 1 1 1 1 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A zinc_ribbon_4 PF13717.6 KKK14445.1 - 0.21 11.6 3.7 16 5.5 0.1 3.6 3 0 0 3 3 3 0 zinc-ribbon domain PAP1 PF08601.10 KKK14445.1 - 4.5 6.9 11.0 1.6 8.3 6.1 2.2 2 0 0 2 2 2 0 Transcription factor PAP1 MRI PF15325.6 KKK14445.1 - 4.6 8.4 6.5 3.9 8.6 3.2 2.5 2 0 0 2 2 2 0 Modulator of retrovirus infection Yip1 PF04893.17 KKK14446.1 - 9.7e-06 25.4 19.5 0.00055 19.7 10.2 2.4 2 0 0 2 2 2 2 Yip1 domain Sporozoite_P67 PF05642.11 KKK14446.1 - 0.52 8.3 6.2 1 7.4 6.2 1.3 1 1 0 1 1 1 0 Sporozoite P67 surface antigen F-box-like PF12937.7 KKK14447.1 - 0.029 14.3 0.1 0.11 12.4 0.0 2.0 2 0 0 2 2 2 0 F-box-like ILVD_EDD PF00920.21 KKK14450.1 - 1.1e-210 700.7 0.5 1.5e-210 700.3 0.5 1.2 1 0 0 1 1 1 1 Dehydratase family Abhydrolase_1 PF00561.20 KKK14451.1 - 6.1e-19 68.7 0.0 2.4e-17 63.5 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KKK14451.1 - 2.1e-07 31.8 0.0 4.8e-07 30.6 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KKK14451.1 - 2.6e-07 30.2 0.0 7.8e-05 22.1 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 DUF3246 PF11596.8 KKK14451.1 - 0.00042 19.8 6.1 0.00064 19.2 6.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3246) Ndr PF03096.14 KKK14451.1 - 0.00095 17.9 0.0 0.0014 17.4 0.0 1.1 1 0 0 1 1 1 1 Ndr family Abhydrolase_4 PF08386.10 KKK14451.1 - 0.0049 17.0 0.0 0.011 15.8 0.0 1.6 1 0 0 1 1 1 1 TAP-like protein SLAIN PF15301.6 KKK14451.1 - 0.01 15.1 6.7 0.017 14.4 6.7 1.2 1 0 0 1 1 1 0 SLAIN motif-containing family SR-25 PF10500.9 KKK14451.1 - 0.011 15.3 11.5 0.011 15.3 11.5 1.4 2 0 0 2 2 1 0 Nuclear RNA-splicing-associated protein DUF3446 PF11928.8 KKK14451.1 - 0.011 16.0 4.5 0.011 16.0 4.5 2.9 4 0 0 4 4 4 0 Early growth response N-terminal domain DUF913 PF06025.12 KKK14451.1 - 0.017 14.1 0.2 0.023 13.7 0.2 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Chorion_2 PF03964.15 KKK14451.1 - 0.03 15.1 1.6 0.054 14.3 1.6 1.4 1 0 0 1 1 1 0 Chorion family 2 THOC2_N PF16134.5 KKK14451.1 - 0.2 10.2 4.7 0.28 9.8 4.7 1.1 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus DUF4611 PF15387.6 KKK14451.1 - 0.25 11.6 4.5 0.8 10.0 3.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Pex14_N PF04695.13 KKK14451.1 - 1.5 9.5 8.5 1.6 9.4 0.6 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region KCT2 PF17818.1 KKK14451.1 - 2.3 8.3 6.8 3.8 7.6 6.8 1.3 1 0 0 1 1 1 0 Keratinocyte-associated gene product TFIIE-A_C PF11521.8 KKK14451.1 - 4.6 7.6 8.9 13 6.1 8.9 1.8 1 0 0 1 1 1 0 C-terminal general transcription factor TFIIE alpha DUF1899 PF08953.11 KKK14452.1 - 1.7e-34 117.5 0.0 4e-34 116.3 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40_4 PF16300.5 KKK14452.1 - 9.3e-20 70.3 0.1 1.7e-19 69.4 0.1 1.5 1 0 0 1 1 1 1 Type of WD40 repeat WD40 PF00400.32 KKK14452.1 - 6.6e-18 64.7 5.5 0.00033 21.4 0.1 5.3 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKK14452.1 - 1.5e-05 25.2 0.0 0.17 12.2 0.1 3.6 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KKK14452.1 - 0.005 15.6 0.2 0.37 9.4 0.2 2.1 1 1 1 2 2 2 2 Nucleoporin Nup120/160 DivIC PF04977.15 KKK14452.1 - 0.8 9.5 2.1 1.6 8.6 2.1 1.4 1 0 0 1 1 1 0 Septum formation initiator SlyX PF04102.12 KKK14452.1 - 1.2 9.8 2.8 0.7 10.6 0.6 1.7 2 0 0 2 2 2 0 SlyX Kinesin PF00225.23 KKK14453.1 - 2.6e-105 352.0 0.3 2.6e-105 352.0 0.3 2.2 2 1 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KKK14453.1 - 5.5e-60 201.6 0.0 1.6e-59 200.2 0.0 1.8 1 0 0 1 1 1 1 Microtubule binding WEMBL PF05701.11 KKK14453.1 - 0.00037 19.3 12.4 0.00037 19.3 12.4 2.6 2 1 1 3 3 3 1 Weak chloroplast movement under blue light AAA_16 PF13191.6 KKK14453.1 - 0.0059 17.0 0.0 0.0059 17.0 0.0 2.4 2 1 0 2 2 2 1 AAA ATPase domain AAA_24 PF13479.6 KKK14453.1 - 0.055 13.2 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KKK14453.1 - 0.078 13.2 0.0 0.078 13.2 0.0 2.8 2 1 1 3 3 3 0 AAA domain RAI16-like PF10257.9 KKK14454.1 - 5.1e-86 288.8 0.0 7.3e-86 288.3 0.0 1.2 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein MFS_1 PF07690.16 KKK14455.1 - 9.8e-18 64.2 53.4 4.3e-16 58.8 27.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KKK14455.1 - 0.0041 15.5 0.1 0.0041 15.5 0.1 1.9 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family CBFD_NFYB_HMF PF00808.23 KKK14456.1 - 1e-15 57.8 2.3 1.7e-15 57.0 2.3 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KKK14456.1 - 2.5e-05 24.6 0.8 2.5e-05 24.6 0.8 1.7 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 zf-C3HC4_3 PF13920.6 KKK14457.1 - 0.00038 20.3 12.2 0.00059 19.6 12.2 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 KKK14457.1 - 2.2 8.2 6.2 3.7 7.5 6.2 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Abhydrolase_1 PF00561.20 KKK14458.1 - 3.6e-28 98.9 0.1 6.9e-28 98.0 0.1 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KKK14458.1 - 4.3e-14 53.6 0.0 5.6e-14 53.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KKK14458.1 - 2.4e-06 27.0 0.0 0.00077 18.8 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 KKK14458.1 - 0.01 14.7 0.0 0.014 14.3 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Chlorophyllase PF07224.11 KKK14458.1 - 0.046 12.7 0.0 0.068 12.2 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase AMP-binding PF00501.28 KKK14459.1 - 2.9e-74 250.2 0.0 4.1e-74 249.7 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 KKK14459.1 - 4e-60 203.2 0.0 5.9e-60 202.6 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein adh_short PF00106.25 KKK14459.1 - 6.2e-37 127.0 2.9 4.4e-36 124.2 1.6 2.3 1 1 1 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KKK14459.1 - 2.8e-25 89.3 4.0 1.9e-24 86.5 1.2 2.6 2 1 1 3 3 3 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KKK14459.1 - 4.9e-14 52.6 0.9 7.7e-10 39.0 1.0 2.5 2 0 0 2 2 2 2 KR domain PP-binding PF00550.25 KKK14459.1 - 3.2e-13 49.8 0.0 9.8e-13 48.3 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.21 KKK14459.1 - 4.8e-13 49.1 0.0 4.4e-08 32.9 0.0 2.5 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KKK14459.1 - 8.3e-07 28.3 0.0 0.0047 16.0 0.0 3.2 3 0 0 3 3 3 2 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 KKK14459.1 - 2.1e-05 23.8 0.1 0.014 14.5 0.0 2.9 3 0 0 3 3 3 2 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 KKK14459.1 - 0.0012 18.3 0.0 0.65 9.3 0.0 2.2 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 KKK14459.1 - 0.0021 18.0 0.6 0.1 12.5 1.4 3.2 3 1 0 3 3 3 1 NAD(P)H-binding DUF4948 PF16306.5 KKK14459.1 - 0.051 13.4 0.0 0.099 12.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4948) ApbA PF02558.16 KKK14459.1 - 0.092 12.4 0.1 0.2 11.3 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Abhydrolase_6 PF12697.7 KKK14460.1 - 6.1e-12 46.6 0.0 7.9e-12 46.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KKK14460.1 - 0.0012 18.1 0.0 0.018 14.4 0.0 2.3 2 1 0 2 2 2 1 Serine aminopeptidase, S33 Lipase_2 PF01674.18 KKK14460.1 - 0.046 13.2 0.0 0.065 12.7 0.0 1.2 1 0 0 1 1 1 0 Lipase (class 2) Abhydrolase_1 PF00561.20 KKK14460.1 - 0.15 11.7 0.0 0.89 9.1 0.0 2.0 2 1 0 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_5 PF12695.7 KKK14460.1 - 0.15 11.8 0.2 0.31 10.8 0.2 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family Epimerase PF01370.21 KKK14461.1 - 1.4e-09 37.8 0.1 2.2e-08 33.9 0.0 2.4 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KKK14461.1 - 0.00023 20.8 0.0 0.0012 18.5 0.0 2.0 1 1 1 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.6 KKK14461.1 - 0.00032 20.7 0.0 0.0011 18.9 0.0 2.0 1 1 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 KKK14461.1 - 0.0013 17.9 0.0 0.002 17.3 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Sugar_tr PF00083.24 KKK14462.1 - 5.5e-91 305.7 20.7 6.8e-91 305.4 20.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKK14462.1 - 2.6e-16 59.5 53.3 1.3e-15 57.2 27.5 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1700 PF08006.11 KKK14462.1 - 0.11 12.1 2.0 1.7 8.1 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1700) DUF2070 PF09843.9 KKK14462.1 - 1.1 7.5 6.4 0.19 10.0 0.4 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2070) Zip PF02535.22 KKK14464.1 - 2.9e-53 181.3 5.7 1.4e-52 179.0 5.7 1.8 1 1 0 1 1 1 1 ZIP Zinc transporter Zn_clus PF00172.18 KKK14465.1 - 1.5e-06 28.2 7.1 3e-06 27.2 7.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KKK14465.1 - 3.1e-06 26.4 0.0 5.2e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain BCMA-Tall_bind PF09257.10 KKK14465.1 - 3.5 7.8 9.4 3.9 7.6 0.2 2.6 2 0 0 2 2 2 0 BCMA, TALL-1 binding FAD_binding_3 PF01494.19 KKK14466.1 - 6.1e-35 121.1 0.0 6.9e-35 120.9 0.0 1.0 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KKK14466.1 - 5.5e-08 32.8 0.1 0.0036 16.9 0.0 2.1 1 1 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KKK14466.1 - 0.00012 21.3 0.1 0.016 14.3 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 KKK14466.1 - 0.00044 19.6 0.0 0.46 9.7 0.1 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KKK14466.1 - 0.0036 17.8 0.0 1.9 9.1 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KKK14466.1 - 0.021 13.7 0.0 0.022 13.6 0.0 1.1 1 0 0 1 1 1 0 Tryptophan halogenase FAD_oxidored PF12831.7 KKK14466.1 - 0.023 14.1 0.0 0.053 12.9 0.0 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KKK14466.1 - 0.036 14.3 0.0 0.08 13.2 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain p450 PF00067.22 KKK14467.1 - 2.6e-12 46.2 0.1 3.2e-11 42.6 0.0 2.2 2 0 0 2 2 2 2 Cytochrome P450 Hemerythrin PF01814.23 KKK14468.1 - 1.7e-10 41.7 0.2 2.4e-10 41.1 0.2 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Dioxygenase_C PF00775.21 KKK14469.1 - 1.3e-09 37.8 0.2 2.1e-09 37.1 0.2 1.2 1 0 0 1 1 1 1 Dioxygenase F-box-like PF12937.7 KKK14470.1 - 0.004 17.0 2.4 0.0056 16.5 1.5 1.8 2 0 0 2 2 2 1 F-box-like DZR PF12773.7 KKK14470.1 - 0.0055 16.7 0.6 0.045 13.8 0.1 2.5 2 1 1 3 3 3 1 Double zinc ribbon F-box PF00646.33 KKK14470.1 - 0.029 14.3 0.7 0.064 13.2 0.7 1.5 1 0 0 1 1 1 0 F-box domain BTB_2 PF02214.22 KKK14471.1 - 3.8e-08 33.6 0.2 0.00069 19.9 0.0 2.5 2 0 0 2 2 2 2 BTB/POZ domain GMC_oxred_N PF00732.19 KKK14472.1 - 2.5e-46 158.4 1.4 2.5e-46 158.4 0.5 1.4 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KKK14472.1 - 1.2e-31 110.2 0.1 9.4e-30 104.0 0.0 2.4 2 0 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KKK14472.1 - 1.5e-07 30.8 0.1 4.8e-06 25.9 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 KKK14472.1 - 9.4e-05 21.8 0.1 0.0002 20.7 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KKK14472.1 - 0.00019 21.6 0.0 0.0028 17.9 0.0 2.8 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KKK14472.1 - 0.00056 19.2 0.1 0.0025 17.1 0.0 1.9 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.19 KKK14472.1 - 0.0014 18.0 0.0 0.0023 17.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KKK14472.1 - 0.0035 16.1 0.1 0.0091 14.7 0.1 1.7 1 0 0 1 1 1 1 HI0933-like protein DAO PF01266.24 KKK14472.1 - 0.012 15.2 4.4 0.14 11.7 4.4 2.3 1 1 0 1 1 1 0 FAD dependent oxidoreductase FAD_oxidored PF12831.7 KKK14472.1 - 0.012 15.0 0.6 0.02 14.3 0.6 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.22 KKK14472.1 - 0.032 13.3 0.1 0.073 12.1 0.0 1.5 2 0 0 2 2 2 0 Glucose inhibited division protein A IlvN PF07991.12 KKK14472.1 - 0.071 12.7 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Pyr_redox PF00070.27 KKK14472.1 - 0.17 12.5 0.0 0.36 11.4 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Acetyltransf_7 PF13508.7 KKK14473.1 - 2.1e-09 37.7 0.0 4.4e-09 36.7 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KKK14473.1 - 1.4e-07 31.5 0.0 0.015 15.2 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KKK14473.1 - 7.1e-06 26.2 0.2 3.6e-05 24.0 0.0 2.2 2 1 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_5 PF13444.6 KKK14473.1 - 3.3e-05 24.5 0.0 0.00029 21.5 0.0 2.2 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KKK14473.1 - 0.00092 19.3 0.0 0.0016 18.5 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 KKK14473.1 - 0.0034 17.5 0.1 0.017 15.2 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KKK14473.1 - 0.071 13.1 0.0 12 6.0 0.0 2.4 2 0 0 2 2 2 0 FR47-like protein Methyltr_RsmB-F PF01189.17 KKK14474.1 - 9.7e-16 58.0 0.0 1e-06 28.6 0.0 3.3 2 1 0 2 2 2 2 16S rRNA methyltransferase RsmB/F cNMP_binding PF00027.29 KKK14475.1 - 1.3e-40 137.4 0.0 4.1e-21 74.8 0.0 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain 2OG-FeII_Oxy_3 PF13640.6 KKK14476.1 - 3.3e-11 43.9 0.0 7e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Forkhead PF00250.18 KKK14477.1 - 2.3e-17 63.0 0.0 4.5e-17 62.1 0.0 1.4 1 0 0 1 1 1 1 Forkhead domain FHA PF00498.26 KKK14477.1 - 1.5e-05 25.2 0.0 2.8e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 FHA domain Dicty_REP PF05086.12 KKK14477.1 - 2.7 5.9 6.6 3.9 5.3 6.6 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein AMPK1_CBM PF16561.5 KKK14478.1 - 3.9e-18 65.4 1.5 7.6e-18 64.5 1.5 1.4 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase CBM_48 PF02922.18 KKK14478.1 - 0.011 16.1 0.1 0.026 14.9 0.1 1.6 1 0 0 1 1 1 0 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) CBM53 PF16760.5 KKK14478.1 - 0.076 13.6 1.2 0.18 12.4 1.2 1.7 1 0 0 1 1 1 0 Starch/carbohydrate-binding module (family 53) Macoilin PF09726.9 KKK14478.1 - 0.48 8.9 6.9 0.88 8.0 6.9 1.3 1 0 0 1 1 1 0 Macoilin family Glutaredoxin PF00462.24 KKK14479.1 - 5.8e-14 52.1 0.2 3.3e-13 49.6 0.0 2.2 2 0 0 2 2 2 1 Glutaredoxin TraF PF13728.6 KKK14479.1 - 0.052 13.4 0.0 0.094 12.5 0.0 1.5 1 0 0 1 1 1 0 F plasmid transfer operon protein DUF3336 PF11815.8 KKK14480.1 - 7e-36 123.0 0.0 5e-35 120.2 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3336) Patatin PF01734.22 KKK14480.1 - 7.4e-15 55.7 0.5 1.6e-14 54.5 0.5 1.5 1 0 0 1 1 1 1 Patatin-like phospholipase Ribosomal_L6 PF00347.23 KKK14481.1 - 2e-23 82.8 2.9 7.3e-11 42.6 1.0 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 PAP1 PF08601.10 KKK14482.1 - 4.1e-133 444.7 15.9 4.1e-133 444.7 15.9 2.9 3 0 0 3 3 3 1 Transcription factor PAP1 bZIP_1 PF00170.21 KKK14482.1 - 2.4e-08 33.9 8.7 5.7e-08 32.7 8.7 1.6 1 0 0 1 1 1 1 bZIP transcription factor SHE3 PF17078.5 KKK14482.1 - 0.0043 16.8 1.9 0.0085 15.8 1.9 1.4 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 DUF16 PF01519.16 KKK14482.1 - 0.061 13.8 0.6 0.15 12.6 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function DUF16 bZIP_2 PF07716.15 KKK14482.1 - 0.068 13.3 12.5 0.22 11.6 11.8 2.1 1 1 0 1 1 1 0 Basic region leucine zipper bZIP_Maf PF03131.17 KKK14482.1 - 0.22 12.0 11.4 0.18 12.4 8.7 2.2 2 0 0 2 2 2 0 bZIP Maf transcription factor HAUS-augmin3 PF14932.6 KKK14482.1 - 0.59 9.7 5.0 0.17 11.5 1.8 1.7 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 DUF2514 PF10721.9 KKK14482.1 - 0.61 10.1 4.3 1.3 9.0 4.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) CDC45 PF02724.14 KKK14482.1 - 2.7 6.2 6.9 4.5 5.4 6.9 1.3 1 0 0 1 1 1 0 CDC45-like protein DUF4407 PF14362.6 KKK14482.1 - 2.7 7.3 4.2 4.4 6.6 4.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4965 PF16335.5 KKK14483.1 - 9.4e-68 227.3 0.6 1.4e-67 226.7 0.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4965) DUF5127 PF17168.4 KKK14483.1 - 4.1e-54 183.8 2.4 6.4e-35 121.0 0.0 2.3 1 1 1 2 2 2 2 Domain of unknown function (DUF5127) DUF2433 PF10360.9 KKK14483.1 - 9e-49 164.7 0.0 6.2e-48 162.0 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2433) DUF1793 PF08760.11 KKK14483.1 - 1e-38 133.4 0.0 2e-38 132.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) DUF4964 PF16334.5 KKK14483.1 - 5.2e-09 35.5 0.1 1.2e-08 34.4 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4964) Metallophos_2 PF12850.7 KKK14483.1 - 0.0026 18.0 0.0 0.0078 16.4 0.0 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 KKK14483.1 - 0.0036 17.8 0.0 0.0084 16.6 0.0 1.7 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Glyco_hydr_116N PF12215.8 KKK14483.1 - 0.015 14.8 0.0 0.04 13.4 0.0 1.8 1 0 0 1 1 1 0 beta-glucosidase 2, glycosyl-hydrolase family 116 N-term Tudor_3 PF18115.1 KKK14484.1 - 1e-06 28.4 0.0 1.8e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain DUF4537 PF15057.6 KKK14484.1 - 0.0085 16.1 0.0 0.014 15.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) LBR_tudor PF09465.10 KKK14484.1 - 0.016 15.0 0.0 0.032 14.0 0.0 1.5 1 0 0 1 1 1 0 Lamin-B receptor of TUDOR domain Fis1_TPR_C PF14853.6 KKK14484.1 - 0.13 12.3 0.3 0.24 11.5 0.3 1.4 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat TP2 PF01254.18 KKK14484.1 - 0.48 11.0 8.2 0.053 14.1 3.3 1.8 2 0 0 2 2 2 0 Nuclear transition protein 2 Pkinase PF00069.25 KKK14487.1 - 6.9e-27 94.5 0.0 9.9e-27 93.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK14487.1 - 3.3e-22 79.0 0.0 5.1e-22 78.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KKK14487.1 - 7.7e-05 22.1 0.0 0.00012 21.5 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KKK14487.1 - 0.0065 15.8 0.0 0.025 13.9 0.0 1.8 1 1 0 1 1 1 1 Kinase-like RIO1 PF01163.22 KKK14487.1 - 0.055 13.1 0.0 0.076 12.6 0.0 1.2 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 KKK14487.1 - 0.096 12.6 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family PIP49_C PF12260.8 KKK14487.1 - 0.13 11.9 0.0 0.35 10.5 0.0 1.6 2 0 0 2 2 2 0 Protein-kinase domain of FAM69 WaaY PF06176.11 KKK14487.1 - 0.14 11.7 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Choline_kinase PF01633.20 KKK14487.1 - 0.18 11.3 0.3 0.92 9.0 0.3 1.9 1 1 1 2 2 2 0 Choline/ethanolamine kinase Abhydrolase_3 PF07859.13 KKK14488.1 - 7.9e-20 71.6 0.0 1e-19 71.3 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KKK14488.1 - 3e-19 69.1 0.0 9.7e-19 67.5 0.0 1.7 1 1 0 1 1 1 1 Steryl acetyl hydrolase DUF2974 PF11187.8 KKK14488.1 - 0.0026 17.4 0.0 0.0042 16.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Mog1 PF04603.12 KKK14488.1 - 0.1 13.0 0.0 0.16 12.3 0.0 1.3 1 0 0 1 1 1 0 Ran-interacting Mog1 protein Peptidase_S9 PF00326.21 KKK14488.1 - 0.1 12.1 0.0 2.1 7.7 0.0 2.3 2 0 0 2 2 2 0 Prolyl oligopeptidase family ADH_zinc_N_2 PF13602.6 KKK14489.1 - 2.1e-29 103.2 0.0 3.4e-29 102.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KKK14489.1 - 1e-17 64.3 0.0 1.7e-17 63.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KKK14489.1 - 0.00021 21.1 0.1 0.0058 16.5 0.0 2.3 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain PALP PF00291.25 KKK14489.1 - 0.029 13.8 0.0 0.042 13.3 0.0 1.2 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme Methyltransf_11 PF08241.12 KKK14489.1 - 0.11 13.2 0.0 0.22 12.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Abhydrolase_3 PF07859.13 KKK14490.1 - 5.7e-32 111.3 0.0 7.2e-25 88.1 0.1 3.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KKK14490.1 - 7.4e-16 58.0 0.0 1.1e-15 57.4 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase ParA PF10609.9 KKK14491.1 - 6.1e-83 278.0 0.0 8.9e-82 274.2 0.0 2.4 1 1 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 KKK14491.1 - 5.5e-13 49.1 0.0 7.9e-10 38.9 0.0 2.2 2 0 0 2 2 2 2 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 KKK14491.1 - 1.4e-09 38.1 0.0 6.1e-08 32.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain MipZ PF09140.11 KKK14491.1 - 1.3e-05 24.7 0.0 1.9e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.15 KKK14491.1 - 0.0016 17.7 0.2 0.0058 15.8 0.2 1.8 2 0 0 2 2 2 1 Anion-transporting ATPase AAA_25 PF13481.6 KKK14491.1 - 0.004 16.8 0.0 0.0099 15.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain Fer4_NifH PF00142.18 KKK14491.1 - 0.039 13.4 0.0 0.72 9.2 0.0 2.1 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family CBP_BcsQ PF06564.12 KKK14491.1 - 0.12 11.8 0.2 0.98 8.8 0.1 2.0 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsQ MeaB PF03308.16 KKK14491.1 - 0.13 11.2 0.2 0.25 10.3 0.2 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB TRAUB PF08164.12 KKK14492.1 - 3.3e-28 98.0 0.2 3.3e-28 98.0 0.2 2.6 2 1 0 2 2 2 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.6 KKK14492.1 - 1.8e-27 96.7 3.4 1.8e-27 96.7 3.4 3.6 3 1 0 3 3 3 1 Apoptosis antagonizing transcription factor DUF1257 PF06868.11 KKK14492.1 - 0.013 15.7 0.0 0.028 14.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1257) DUF5383 PF17355.2 KKK14492.1 - 4.8 7.6 7.9 17 5.8 7.9 2.0 1 0 0 1 1 1 0 Family of unknown function (DUF5383) Sugar_tr PF00083.24 KKK14493.1 - 4.5e-27 95.0 9.8 5.3e-14 51.9 4.8 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KKK14493.1 - 8.4e-16 57.8 26.7 5.7e-11 41.9 11.0 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF3325 PF11804.8 KKK14493.1 - 0.47 10.6 6.6 0.15 12.2 0.8 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3325) APH PF01636.23 KKK14496.1 - 5.6e-17 62.5 0.1 2.9e-16 60.1 0.1 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KKK14496.1 - 1.4e-06 27.8 0.0 0.051 12.9 0.0 2.2 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 KKK14496.1 - 0.00022 20.9 0.0 0.00037 20.1 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 KKK14496.1 - 0.0066 16.1 0.1 0.99 9.0 0.0 2.1 2 0 0 2 2 2 2 RIO1 family APH_6_hur PF04655.14 KKK14496.1 - 0.086 12.2 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Aminoglycoside/hydroxyurea antibiotic resistance kinase Pkinase PF00069.25 KKK14496.1 - 0.19 11.1 0.0 0.25 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain Inositol_P PF00459.25 KKK14498.1 - 1.8e-70 237.6 0.0 2e-70 237.4 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family DUF676 PF05057.14 KKK14499.1 - 3.1e-41 141.3 0.0 1.2e-36 126.3 0.0 3.2 1 1 0 1 1 1 1 Putative serine esterase (DUF676) LCAT PF02450.15 KKK14499.1 - 0.061 12.5 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DUF915 PF06028.11 KKK14499.1 - 0.065 12.6 0.1 0.12 11.7 0.1 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) PGAP1 PF07819.13 KKK14499.1 - 0.084 12.6 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein PLU-1 PF08429.11 KKK14501.1 - 7.3e-112 373.9 14.3 1.1e-108 363.5 12.8 2.2 2 0 0 2 2 2 2 PLU-1-like protein JmjC PF02373.22 KKK14501.1 - 2.7e-44 150.2 0.2 5.8e-44 149.2 0.2 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase ARID PF01388.21 KKK14501.1 - 1.8e-21 76.6 0.1 5.2e-21 75.1 0.1 1.9 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain PHD PF00628.29 KKK14501.1 - 3.5e-17 62.0 31.7 4.5e-10 39.3 7.3 3.5 3 0 0 3 3 3 2 PHD-finger JmjN PF02375.17 KKK14501.1 - 1.1e-16 60.5 2.0 2.9e-16 59.1 2.0 1.8 1 0 0 1 1 1 1 jmjN domain zf-C5HC2 PF02928.16 KKK14501.1 - 1.4e-12 47.8 3.5 4.9e-12 46.0 3.5 2.1 1 0 0 1 1 1 1 C5HC2 zinc finger zf-PHD-like PF15446.6 KKK14501.1 - 0.018 14.6 9.6 0.076 12.6 1.1 2.8 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain DNApol3-delta_C PF09115.10 KKK14501.1 - 0.18 12.4 0.1 0.7 10.4 0.0 2.0 2 0 0 2 2 2 0 DNA polymerase III, delta subunit, C terminal Spore_III_AB PF09548.10 KKK14501.1 - 0.3 11.2 4.6 1.4 9.0 1.0 2.6 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) PHD_4 PF16866.5 KKK14501.1 - 2.3 8.4 18.6 0.95 9.6 4.7 2.9 2 0 0 2 2 2 0 PHD-finger zf-RING_2 PF13639.6 KKK14501.1 - 3.2 8.1 24.9 3.8 7.9 8.8 2.9 2 0 0 2 2 2 0 Ring finger domain Zf_RING PF16744.5 KKK14501.1 - 6.4 7.0 20.3 2.2 8.4 6.2 3.4 3 0 0 3 3 3 0 KIAA1045 RING finger zf-rbx1 PF12678.7 KKK14501.1 - 6.4 7.1 18.0 0.8 10.0 5.5 3.0 2 0 0 2 2 2 0 RING-H2 zinc finger domain Pkinase PF00069.25 KKK14502.1 - 2.6e-70 236.8 0.0 3.6e-70 236.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK14502.1 - 4.1e-34 118.0 0.0 6.6e-34 117.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KKK14502.1 - 0.00037 19.9 0.1 0.0016 17.8 0.0 1.8 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.14 KKK14502.1 - 0.015 14.7 0.4 0.027 13.8 0.4 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KKK14502.1 - 0.028 13.2 0.0 0.051 12.4 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 KKK14502.1 - 0.048 12.6 0.1 0.37 9.7 0.0 1.9 2 0 0 2 2 2 0 Haspin like kinase domain Thymidylate_kin PF02223.17 KKK14503.1 - 2.6e-46 157.6 0.0 3e-46 157.4 0.0 1.0 1 0 0 1 1 1 1 Thymidylate kinase KTI12 PF08433.10 KKK14503.1 - 0.0032 17.0 0.0 0.0076 15.7 0.0 1.5 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_28 PF13521.6 KKK14503.1 - 0.0091 16.3 0.0 0.013 15.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain CPT PF07931.12 KKK14503.1 - 0.014 15.2 0.0 0.026 14.4 0.0 1.4 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_18 PF13238.6 KKK14503.1 - 0.17 12.4 0.0 0.51 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain NDK PF00334.19 KKK14504.1 - 4e-54 182.3 0.0 4.5e-54 182.1 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase GIY-YIG PF01541.24 KKK14505.1 - 2.1e-12 47.1 0.0 3.6e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 GIY-YIG catalytic domain FANCL_C PF11793.8 KKK14505.1 - 0.00022 21.4 5.4 0.00037 20.6 5.4 1.3 1 0 0 1 1 1 1 FANCL C-terminal domain Prok-RING_1 PF14446.6 KKK14505.1 - 0.27 11.2 8.8 0.057 13.4 4.3 2.0 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 TP1 PF02079.16 KKK14505.1 - 5.3 7.0 10.1 2.2 8.2 1.5 2.4 2 0 0 2 2 2 0 Nuclear transition protein 1 MTHFR PF02219.17 KKK14506.1 - 4.8e-89 298.5 0.0 6.4e-89 298.1 0.0 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase Protein_K PF12283.8 KKK14506.1 - 0.079 13.2 0.3 0.39 11.0 0.1 2.0 2 0 0 2 2 2 0 Bacteriophage protein K TGT PF01702.18 KKK14507.1 - 4.2e-70 236.6 0.0 5.8e-70 236.2 0.0 1.1 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase FLILHELTA PF10306.9 KKK14508.1 - 9e-31 106.1 0.2 2.2e-30 104.9 0.0 1.7 2 0 0 2 2 2 1 Hypothetical protein FLILHELTA DUF1279 PF06916.13 KKK14508.1 - 0.00088 19.8 0.0 0.0013 19.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) NMT1 PF09084.11 KKK14509.1 - 3.7e-05 23.8 0.0 0.00021 21.3 0.0 1.9 1 1 1 2 2 2 1 NMT1/THI5 like NMT1_3 PF16868.5 KKK14509.1 - 0.011 15.2 0.0 0.016 14.7 0.0 1.1 1 0 0 1 1 1 0 NMT1-like family Phosphonate-bd PF12974.7 KKK14509.1 - 0.15 11.6 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 ABC transporter, phosphonate, periplasmic substrate-binding protein tRNA-synt_1c PF00749.21 KKK14510.1 - 3.9e-105 351.2 0.0 5.4e-105 350.7 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 KKK14510.1 - 1.2e-43 149.1 0.3 2.7e-43 147.9 0.3 1.7 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C_2 PF13410.6 KKK14510.1 - 0.0017 18.3 0.0 0.0044 17.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KKK14510.1 - 0.025 14.7 0.0 0.3 11.3 0.0 2.5 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Glutaredoxin2_C PF04399.13 KKK14510.1 - 0.047 13.5 0.0 0.14 12.0 0.0 1.7 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain GST_C PF00043.25 KKK14510.1 - 0.082 13.1 0.0 0.24 11.7 0.0 1.8 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain tRNA-synt_1e PF01406.19 KKK14510.1 - 0.16 11.3 0.3 0.38 10.1 0.2 1.6 1 1 1 2 2 2 0 tRNA synthetases class I (C) catalytic domain E1-E2_ATPase PF00122.20 KKK14511.1 - 9.4e-35 119.8 5.5 3.6e-32 111.4 4.3 3.3 2 1 0 2 2 2 2 E1-E2 ATPase Hydrolase PF00702.26 KKK14511.1 - 1.3e-18 68.1 0.0 3.6e-18 66.6 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KKK14511.1 - 7.8e-09 35.1 0.0 1.6e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KKK14511.1 - 0.0047 16.7 0.0 0.02 14.7 0.0 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Ribosomal_L1 PF00687.21 KKK14512.1 - 3.1e-30 105.5 0.0 4.4e-30 105.0 0.0 1.3 1 1 0 1 1 1 1 Ribosomal protein L1p/L10e family Pyr_redox_2 PF07992.14 KKK14513.1 - 6.1e-11 42.1 0.0 6.2e-05 22.4 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KKK14513.1 - 0.021 13.5 0.0 0.039 12.6 0.0 1.4 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_8 PF13450.6 KKK14513.1 - 0.027 14.7 0.1 0.13 12.5 0.0 2.3 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KKK14513.1 - 0.032 13.3 0.0 0.21 10.6 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain FAD_binding_3 PF01494.19 KKK14513.1 - 0.059 12.6 0.2 0.11 11.8 0.2 1.4 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.17 KKK14513.1 - 0.1 11.8 0.0 0.2 10.8 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Glyco_hydro_18 PF00704.28 KKK14514.1 - 1.1e-19 71.3 2.1 3.4e-19 69.7 2.1 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 DUF4611 PF15387.6 KKK14514.1 - 0.034 14.3 3.1 0.065 13.5 3.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) PBP_sp32 PF07222.12 KKK14514.1 - 0.038 13.4 2.4 0.059 12.8 2.4 1.3 1 0 0 1 1 1 0 Proacrosin binding protein sp32 DUF4834 PF16118.5 KKK14514.1 - 0.04 14.9 0.8 0.04 14.9 0.8 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Sporozoite_P67 PF05642.11 KKK14514.1 - 0.058 11.5 0.6 0.071 11.2 0.6 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen POPLD PF08170.12 KKK14514.1 - 0.17 12.3 2.6 9.2 6.7 0.0 2.3 2 0 0 2 2 2 0 POPLD (NUC188) domain PAXIP1_C PF15364.6 KKK14514.1 - 0.26 11.6 7.9 0.48 10.7 5.8 2.1 2 0 0 2 2 2 0 PAXIP1-associated-protein-1 C term PTIP binding protein DUF1840 PF08895.11 KKK14514.1 - 0.38 11.1 2.5 8.2 6.8 2.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) FAM176 PF14851.6 KKK14514.1 - 0.71 9.5 5.2 1.3 8.7 5.2 1.3 1 0 0 1 1 1 0 FAM176 family PBP1_TM PF14812.6 KKK14514.1 - 0.82 10.1 4.7 1.4 9.4 4.7 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Pox_Ag35 PF03286.14 KKK14514.1 - 1.5 8.6 4.6 2.3 7.9 4.6 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Tim54 PF11711.8 KKK14514.1 - 5.3 5.7 6.4 1 8.1 3.0 1.4 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 Glyco_hydro_31 PF01055.26 KKK14515.1 - 2.4e-138 462.0 6.7 3.4e-138 461.5 6.7 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 PQ-loop PF04193.14 KKK14515.1 - 1.3e-19 69.7 10.0 1.1e-13 50.7 0.3 2.8 3 0 0 3 3 3 2 PQ loop repeat Gal_mutarotas_2 PF13802.6 KKK14515.1 - 3.7e-18 65.6 0.7 5e-17 62.0 0.1 2.5 2 0 0 2 2 2 1 Galactose mutarotase-like DUF5110 PF17137.4 KKK14515.1 - 1.4e-06 28.5 0.1 3.9e-06 27.0 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF5110) ER_lumen_recept PF00810.18 KKK14515.1 - 0.037 14.9 0.9 0.076 13.8 0.9 1.6 1 0 0 1 1 1 0 ER lumen protein retaining receptor MFS_1 PF07690.16 KKK14522.1 - 1.9e-42 145.5 25.2 2.2e-42 145.2 25.2 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KKK14522.1 - 9.4e-12 44.5 1.5 9.4e-12 44.5 1.5 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.20 KKK14522.1 - 0.16 10.2 2.9 1.6 7.0 0.3 2.3 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family FAD_binding_3 PF01494.19 KKK14523.1 - 2.1e-72 244.3 0.3 2e-71 241.1 0.3 2.0 1 1 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 KKK14523.1 - 2.7e-29 102.3 0.0 5.4e-29 101.4 0.0 1.5 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain SE PF08491.10 KKK14523.1 - 0.0049 16.0 0.0 0.018 14.1 0.0 1.8 2 0 0 2 2 2 1 Squalene epoxidase Lactamase_B PF00753.27 KKK14523.1 - 0.053 13.5 0.1 0.36 10.8 0.1 2.2 1 1 0 1 1 1 0 Metallo-beta-lactamase superfamily Pyr_redox_2 PF07992.14 KKK14523.1 - 0.054 12.7 0.1 0.14 11.4 0.1 1.7 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KKK14523.1 - 0.11 12.7 0.1 0.38 11.0 0.1 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KKK14523.1 - 0.13 10.9 0.0 0.21 10.3 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Lycopene_cycl PF05834.12 KKK14523.1 - 0.14 11.2 0.1 0.21 10.6 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_binding_8 PF13450.6 KKK14524.1 - 3.3e-12 46.4 0.0 6.8e-12 45.4 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.19 KKK14524.1 - 5.4e-12 44.9 3.3 1.8e-11 43.2 0.9 2.5 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KKK14524.1 - 3.3e-10 39.7 0.0 4.4e-08 32.7 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KKK14524.1 - 5.1e-06 25.9 0.7 0.001 18.3 0.0 3.2 3 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 KKK14524.1 - 3.1e-05 23.7 0.6 0.0045 16.6 0.2 2.4 2 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KKK14524.1 - 0.00043 19.6 0.0 0.01 15.1 0.0 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KKK14524.1 - 0.0019 17.5 0.0 0.14 11.4 0.0 2.4 2 0 0 2 2 2 1 Thi4 family NAD_binding_9 PF13454.6 KKK14524.1 - 0.0047 16.9 1.7 0.022 14.7 0.0 2.9 3 1 0 3 3 3 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 KKK14524.1 - 0.23 10.5 0.0 0.36 9.8 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain DUF1033 PF06279.11 KKK14524.1 - 4.8 7.4 6.3 0.67 10.1 0.9 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1033) Fungal_trans PF04082.18 KKK14525.1 - 1.3e-09 37.5 1.8 2.1e-09 36.8 1.8 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK14525.1 - 3.6e-07 30.2 5.3 1e-06 28.8 5.3 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2 PF00096.26 KKK14525.1 - 0.025 15.0 4.4 0.1 13.1 4.4 2.2 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KKK14525.1 - 0.9 10.6 11.2 0.057 14.3 3.7 3.1 2 0 0 2 2 2 0 C2H2-type zinc finger DUF1712 PF08217.11 KKK14526.1 - 3.9e-14 52.1 0.0 1.2e-13 50.5 0.0 1.7 2 0 0 2 2 2 1 Fungal domain of unknown function (DUF1712) Alg14 PF08660.11 KKK14527.1 - 3.6e-56 189.8 0.0 6.5e-56 189.0 0.0 1.4 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like adh_short_C2 PF13561.6 KKK14527.1 - 1.4e-43 149.2 0.5 1.8e-43 148.8 0.5 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KKK14527.1 - 7.3e-36 123.5 0.1 1.1e-35 122.8 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KKK14527.1 - 1.4e-08 34.9 0.3 2.2e-08 34.2 0.3 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KKK14527.1 - 0.076 12.5 0.0 5.7 6.3 0.0 2.5 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family DUF624 PF04854.14 KKK14527.1 - 0.15 12.2 0.2 0.43 10.7 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function, DUF624 Formyl_trans_N PF00551.19 KKK14528.1 - 8.4e-20 71.3 0.0 3e-19 69.5 0.0 1.8 2 0 0 2 2 2 1 Formyl transferase Formyl_trans_C PF02911.18 KKK14528.1 - 0.0012 19.1 0.1 0.0031 17.7 0.1 1.7 1 1 0 1 1 1 1 Formyl transferase, C-terminal domain Ima1_N PF09779.9 KKK14529.1 - 2.5e-35 122.2 1.8 5.4e-35 121.2 1.8 1.6 1 0 0 1 1 1 1 Ima1 N-terminal domain OrfB_Zn_ribbon PF07282.11 KKK14529.1 - 0.71 9.8 2.4 1.8 8.5 2.4 1.7 1 0 0 1 1 1 0 Putative transposase DNA-binding domain DZR PF12773.7 KKK14529.1 - 3.7 7.6 8.4 3.4 7.8 1.5 2.6 2 1 0 2 2 2 0 Double zinc ribbon Ribonuc_L-PSP PF01042.21 KKK14535.1 - 2.6e-23 82.3 0.0 3e-23 82.1 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP APH PF01636.23 KKK14537.1 - 8.7e-15 55.3 0.0 2e-14 54.1 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family TPR_19 PF14559.6 KKK14544.1 - 8.1e-19 67.9 17.9 5.7e-08 33.2 0.0 8.1 6 2 3 9 9 9 3 Tetratricopeptide repeat TPR_2 PF07719.17 KKK14544.1 - 7.4e-12 44.4 23.7 0.0073 16.3 0.0 9.1 10 0 0 10 10 9 4 Tetratricopeptide repeat TPR_17 PF13431.6 KKK14544.1 - 7.6e-12 44.7 2.0 0.014 15.7 0.0 6.6 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_11 PF13414.6 KKK14544.1 - 5e-11 42.1 10.7 0.01 15.5 0.0 6.8 6 1 1 7 7 7 3 TPR repeat TPR_14 PF13428.6 KKK14544.1 - 7.1e-10 38.9 25.4 0.00088 19.9 1.2 9.4 10 1 1 11 11 8 2 Tetratricopeptide repeat TPR_1 PF00515.28 KKK14544.1 - 1.7e-09 37.1 17.9 0.022 14.6 0.0 9.0 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_16 PF13432.6 KKK14544.1 - 1.9e-09 38.0 16.3 3.2e-05 24.5 0.0 5.8 6 0 0 6 6 6 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KKK14544.1 - 5.4e-09 36.2 12.6 0.053 13.8 0.0 6.9 7 1 0 7 7 7 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 KKK14544.1 - 3.4e-08 33.0 16.0 1.5 9.1 0.0 8.4 10 0 0 10 10 8 2 Tetratricopeptide repeat TPR_8 PF13181.6 KKK14544.1 - 7.5e-07 28.9 14.4 1.3 9.4 0.0 8.2 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_12 PF13424.6 KKK14544.1 - 3.4e-06 27.2 12.3 0.041 14.2 0.1 6.4 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_20 PF14561.6 KKK14544.1 - 0.01 16.1 7.1 19 5.6 0.0 5.4 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 KKK14544.1 - 0.011 16.3 8.0 50 4.8 0.2 7.0 8 0 0 8 8 6 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 KKK14544.1 - 0.034 14.6 1.8 9.9 6.6 0.0 2.9 3 0 0 3 3 2 0 Alkyl sulfatase dimerisation TPR_9 PF13371.6 KKK14544.1 - 0.041 14.0 0.3 0.041 14.0 0.3 4.5 4 1 2 6 6 5 0 Tetratricopeptide repeat CDC45 PF02724.14 KKK14544.1 - 0.26 9.6 3.0 0.45 8.7 3.0 1.3 1 0 0 1 1 1 0 CDC45-like protein NARP1 PF12569.8 KKK14544.1 - 0.71 8.7 6.7 8.5 5.2 0.1 3.3 2 2 1 3 3 3 0 NMDA receptor-regulated protein 1 BTAD PF03704.17 KKK14544.1 - 0.87 10.0 8.1 0.36 11.2 1.5 3.5 3 1 2 5 5 5 0 Bacterial transcriptional activator domain DUF3336 PF11815.8 KKK14545.1 - 1.5e-47 160.8 2.1 1.5e-47 160.8 2.1 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3336) Patatin PF01734.22 KKK14545.1 - 4e-18 66.4 0.4 2.2e-16 60.6 0.1 3.2 2 1 0 2 2 2 1 Patatin-like phospholipase AAA_lid_2 PF17863.1 KKK14545.1 - 0.17 11.8 0.0 0.4 10.6 0.0 1.6 1 0 0 1 1 1 0 AAA lid domain Pyr_redox_2 PF07992.14 KKK14546.1 - 8.5e-13 48.2 0.0 2.4e-11 43.4 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ABC_tran PF00005.27 KKK14546.1 - 1.6e-07 31.9 0.0 4.5e-07 30.5 0.0 1.7 1 0 0 1 1 1 1 ABC transporter Pyr_redox PF00070.27 KKK14546.1 - 0.0066 17.0 0.1 2.2 8.9 0.0 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AAA_29 PF13555.6 KKK14546.1 - 0.012 15.4 0.0 0.029 14.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Amino_oxidase PF01593.24 KKK14546.1 - 0.15 11.3 0.0 0.42 9.8 0.0 1.7 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase G-alpha PF00503.20 KKK14546.1 - 0.23 10.6 0.0 0.4 9.8 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit SAM_2 PF07647.17 KKK14547.1 - 4.7e-08 33.0 0.1 1.1e-07 31.8 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KKK14547.1 - 0.00021 21.6 0.2 0.00055 20.3 0.2 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DUF4508 PF14969.6 KKK14547.1 - 0.11 12.8 0.2 0.24 11.7 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4508) DHC_N1 PF08385.12 KKK14547.1 - 0.14 10.8 1.6 0.28 9.8 1.6 1.5 1 1 0 1 1 1 0 Dynein heavy chain, N-terminal region 1 RdRP PF05183.12 KKK14548.1 - 2e-183 611.2 0.0 2.6e-183 610.9 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase RRM_1 PF00076.22 KKK14548.1 - 0.021 14.7 0.0 0.055 13.3 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DNA_binding_2 PF13724.6 KKK14548.1 - 0.1 13.0 0.2 0.28 11.6 0.0 1.8 2 0 0 2 2 2 0 DNA-binding domain Fungal_trans_2 PF11951.8 KKK14549.1 - 6.6e-05 21.9 1.7 0.00011 21.1 0.2 1.9 2 1 0 2 2 2 1 Fungal specific transcription factor domain DNA_pol_B_thumb PF14791.6 KKK14550.1 - 1.5e-20 73.1 2.9 2.3e-20 72.5 0.2 2.3 2 0 0 2 2 2 1 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.9 KKK14550.1 - 9.4e-16 57.4 0.1 1.8e-15 56.5 0.1 1.5 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda DNA_pol_B_palm PF14792.6 KKK14550.1 - 3e-15 56.4 1.2 1.9e-14 53.8 1.2 2.3 1 1 0 1 1 1 1 DNA polymerase beta palm HHH_8 PF14716.6 KKK14550.1 - 1.3e-10 41.5 0.0 1.8e-09 37.8 0.1 2.3 2 0 0 2 2 2 1 Helix-hairpin-helix domain NTP_transf_2 PF01909.23 KKK14550.1 - 0.011 16.0 0.1 0.048 14.0 0.1 2.1 1 1 0 1 1 1 0 Nucleotidyltransferase domain BRCT_2 PF16589.5 KKK14550.1 - 0.062 13.7 0.0 0.14 12.6 0.0 1.6 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain HHH_5 PF14520.6 KKK14550.1 - 0.12 12.9 0.0 0.31 11.7 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix domain IMS_HHH PF11798.8 KKK14550.1 - 0.17 12.3 0.0 0.54 10.7 0.0 1.8 1 0 0 1 1 1 0 IMS family HHH motif Translin PF01997.16 KKK14551.1 - 2.3e-49 168.2 0.0 2.7e-49 168.0 0.0 1.0 1 0 0 1 1 1 1 Translin family Rx_N PF18052.1 KKK14551.1 - 0.049 13.9 1.6 4.5 7.6 1.0 3.2 2 1 0 2 2 2 0 Rx N-terminal domain DIM1 PF02966.16 KKK14552.1 - 9e-69 229.4 0.3 1e-68 229.2 0.3 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.20 KKK14552.1 - 0.14 12.1 0.0 0.19 11.7 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin Fungal_trans PF04082.18 KKK14553.1 - 2.7e-29 102.0 0.0 4.5e-29 101.3 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK14553.1 - 2.7e-11 43.4 12.6 4.6e-11 42.7 12.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4446 PF14584.6 KKK14553.1 - 0.11 12.5 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) SCNM1_acidic PF15805.5 KKK14554.1 - 0.04 13.6 0.5 0.086 12.6 0.5 1.4 1 0 0 1 1 1 0 Acidic C-terminal region of sodium channel modifier 1 SCNM1 F-box-like PF12937.7 KKK14554.1 - 0.34 10.8 6.5 0.054 13.4 1.4 2.5 2 1 0 2 2 2 0 F-box-like PHD PF00628.29 KKK14556.1 - 7.6e-11 41.7 7.5 1.7e-10 40.6 7.5 1.6 1 0 0 1 1 1 1 PHD-finger Nucleo_P87 PF07267.11 KKK14556.1 - 3.9 6.2 4.9 6.3 5.5 4.9 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Fungal_trans_2 PF11951.8 KKK14557.1 - 6.1e-06 25.3 0.0 4.5e-05 22.4 0.0 2.2 2 0 0 2 2 2 1 Fungal specific transcription factor domain GSHPx PF00255.19 KKK14558.1 - 4.8e-39 132.3 0.0 6.4e-39 131.9 0.0 1.2 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 KKK14558.1 - 0.0077 16.1 0.0 0.018 15.0 0.0 1.8 1 1 0 1 1 1 1 AhpC/TSA family Pcc1 PF09341.10 KKK14559.1 - 1.2e-31 108.6 0.1 1.5e-31 108.4 0.1 1.1 1 0 0 1 1 1 1 Transcription factor Pcc1 DUF5405 PF17399.2 KKK14560.1 - 0.31 11.3 2.5 12 6.2 0.1 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF5405) DSPn PF14671.6 KKK14561.1 - 4e-43 147.2 0.0 4.8e-41 140.5 0.0 2.7 2 1 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 KKK14561.1 - 5.5e-16 58.6 0.1 1.4e-15 57.3 0.0 1.6 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KKK14561.1 - 8.2e-06 25.6 0.0 1.4e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.13 KKK14561.1 - 0.026 14.1 0.0 0.05 13.2 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family Fungal_trans_2 PF11951.8 KKK14562.1 - 5.8e-09 35.2 0.4 9.7e-09 34.5 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK14562.1 - 1.2e-07 31.7 8.5 2.2e-07 30.9 8.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-RING_2 PF13639.6 KKK14564.1 - 7.5e-11 42.2 7.8 1.2e-10 41.6 7.8 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KKK14564.1 - 4.2e-09 36.0 2.3 4.2e-09 36.0 2.3 1.7 2 0 0 2 2 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KKK14564.1 - 9.2e-08 31.8 6.8 1.7e-07 30.9 6.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KKK14564.1 - 3.4e-07 30.0 5.9 6.2e-07 29.2 5.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KKK14564.1 - 5e-07 29.7 2.8 9.8e-07 28.7 2.8 1.5 1 0 0 1 1 1 1 RING-type zinc-finger Zn_ribbon_17 PF17120.5 KKK14564.1 - 0.00012 21.6 7.0 0.00022 20.7 7.0 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-rbx1 PF12678.7 KKK14564.1 - 0.00022 21.5 10.4 0.00071 19.8 10.4 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KKK14564.1 - 0.00024 21.0 5.9 0.0004 20.3 5.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KKK14564.1 - 0.00029 20.6 6.7 0.00074 19.3 6.4 1.8 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING-like PF08746.11 KKK14564.1 - 0.0018 18.5 4.3 0.0031 17.8 4.3 1.4 1 0 0 1 1 1 1 RING-like domain zf-ANAPC11 PF12861.7 KKK14564.1 - 0.0038 17.2 2.4 0.0062 16.6 2.4 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 KKK14564.1 - 0.0065 16.3 5.0 0.012 15.5 5.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Adeno_E3_CR2 PF02439.15 KKK14564.1 - 0.037 13.8 0.1 0.059 13.1 0.1 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 FANCL_C PF11793.8 KKK14564.1 - 0.1 12.8 7.0 0.95 9.7 7.1 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain Zn_Tnp_IS1595 PF12760.7 KKK14564.1 - 0.1 12.6 0.9 0.1 12.6 0.9 2.1 1 1 1 2 2 2 0 Transposase zinc-ribbon domain RINGv PF12906.7 KKK14564.1 - 0.1 12.7 6.6 0.17 12.0 5.9 1.8 1 1 0 1 1 1 0 RING-variant domain zf-RING_4 PF14570.6 KKK14564.1 - 0.19 11.6 3.9 0.37 10.6 3.9 1.5 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Elf1 PF05129.13 KKK14564.1 - 0.51 10.4 4.2 12 6.0 0.4 2.4 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like zf-C3HC4_4 PF15227.6 KKK14564.1 - 0.55 10.4 6.7 9.7 6.4 6.6 2.2 1 1 2 3 3 3 0 zinc finger of C3HC4-type, RING XPA_N PF01286.18 KKK14564.1 - 0.58 10.3 6.8 0.53 10.4 1.1 2.3 2 0 0 2 2 2 0 XPA protein N-terminal Zf_RING PF16744.5 KKK14564.1 - 0.66 10.1 6.9 3.2 7.9 6.9 1.9 1 1 0 1 1 1 0 KIAA1045 RING finger CNH PF00780.22 KKK14565.1 - 2.1e-68 230.9 0.0 3.4e-68 230.2 0.0 1.3 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.20 KKK14565.1 - 3.2e-32 112.3 0.7 6.4e-32 111.3 0.7 1.5 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.6 KKK14565.1 - 5.6e-11 42.7 0.0 2.8e-10 40.4 0.0 2.3 1 1 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 KKK14565.1 - 0.006 17.1 0.0 0.026 15.0 0.0 2.1 2 0 0 2 2 2 1 PH domain RabGAP-TBC PF00566.18 KKK14566.1 - 1.3e-47 162.3 0.0 2.6e-47 161.3 0.0 1.6 1 0 0 1 1 1 1 Rab-GTPase-TBC domain GRAM PF02893.20 KKK14566.1 - 0.0037 17.1 0.0 0.008 16.0 0.0 1.5 1 0 0 1 1 1 1 GRAM domain EF-hand_6 PF13405.6 KKK14566.1 - 0.007 16.2 0.7 0.042 13.8 0.3 2.7 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.6 KKK14566.1 - 0.09 13.2 0.1 0.6 10.6 0.1 2.5 2 1 0 2 2 2 0 EF-hand domain pair EF-hand_1 PF00036.32 KKK14566.1 - 0.12 12.0 0.3 1.1 8.9 1.1 2.2 2 0 0 2 2 2 0 EF hand PikAIV_N PF18605.1 KKK14566.1 - 3.1 7.5 5.2 0.44 10.2 0.3 2.1 2 0 0 2 2 2 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain Exo_endo_phos PF03372.23 KKK14567.1 - 7.1e-05 22.4 0.0 0.0002 21.0 0.0 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family TPK_B1_binding PF04265.14 KKK14568.1 - 0.029 14.1 0.0 0.081 12.6 0.0 1.7 1 0 0 1 1 1 0 Thiamin pyrophosphokinase, vitamin B1 binding domain adh_short_C2 PF13561.6 KKK14569.1 - 1e-35 123.4 0.5 1.4e-34 119.7 0.5 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KKK14569.1 - 6.1e-27 94.3 1.3 2.5e-26 92.4 1.3 1.8 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KKK14569.1 - 3.1e-06 27.2 0.1 5.7e-06 26.4 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KKK14569.1 - 0.078 12.4 0.2 0.19 11.2 0.2 1.8 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family TPP_enzyme_N PF02776.18 KKK14571.1 - 5e-33 114.1 0.6 8.6e-33 113.4 0.0 1.7 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain ADH_N PF08240.12 KKK14571.1 - 1.9e-25 88.9 0.4 3.9e-25 87.9 0.4 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KKK14571.1 - 2.9e-24 85.5 0.1 8.5e-24 84.0 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase TPP_enzyme_M PF00205.22 KKK14571.1 - 2.3e-21 76.0 0.0 6.7e-20 71.2 0.0 2.7 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 KKK14571.1 - 7.3e-18 64.8 0.7 3.3e-17 62.7 0.0 2.5 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain adh_short PF00106.25 KKK14571.1 - 0.048 13.1 0.0 0.091 12.2 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase DUF2284 PF10050.9 KKK14571.1 - 0.054 13.2 0.2 1.8 8.3 0.0 2.3 2 0 0 2 2 2 0 Predicted metal-binding protein (DUF2284) DUF1772 PF08592.11 KKK14572.1 - 0.0003 21.1 0.1 0.00055 20.3 0.1 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF1772) APG5 PF04106.12 KKK14580.1 - 2.5e-34 118.9 0.0 3.5e-34 118.4 0.0 1.2 1 0 0 1 1 1 1 Autophagy protein Apg5 OB_NTP_bind PF07717.16 KKK14581.1 - 2.4e-23 82.3 0.1 9.5e-23 80.4 0.1 2.0 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 KKK14581.1 - 3.1e-20 72.5 0.0 9.5e-20 70.9 0.0 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KKK14581.1 - 1.2e-10 41.7 0.0 5.1e-10 39.7 0.0 2.1 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.29 KKK14581.1 - 7.9e-07 29.0 0.2 1.4e-06 28.2 0.2 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KKK14581.1 - 6.9e-06 26.4 0.0 2.5e-05 24.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 KKK14581.1 - 0.00028 20.6 0.4 0.00098 18.8 0.4 1.9 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_19 PF13245.6 KKK14581.1 - 0.0029 18.0 0.2 0.006 16.9 0.2 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KKK14581.1 - 0.0036 17.0 0.0 0.0069 16.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain Flavi_DEAD PF07652.14 KKK14581.1 - 0.0048 16.9 1.6 0.0052 16.8 0.3 1.7 2 0 0 2 2 2 1 Flavivirus DEAD domain T2SSE PF00437.20 KKK14581.1 - 0.02 13.9 0.0 0.04 13.0 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_7 PF12775.7 KKK14581.1 - 0.039 13.5 0.0 0.097 12.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region ResIII PF04851.15 KKK14581.1 - 0.072 13.1 0.0 14 5.7 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit IstB_IS21 PF01695.17 KKK14581.1 - 0.12 12.0 0.1 2.4 7.9 0.1 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein DUF2075 PF09848.9 KKK14581.1 - 0.15 11.3 0.0 0.23 10.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) PRMT5_TIM PF17285.2 KKK14582.1 - 2.1e-75 253.2 0.0 2.8e-75 252.8 0.0 1.2 1 0 0 1 1 1 1 PRMT5 TIM barrel domain PRMT5 PF05185.16 KKK14582.1 - 5.9e-66 221.6 0.0 9.8e-66 220.9 0.0 1.4 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PRMT5_C PF17286.2 KKK14582.1 - 1.5e-58 197.6 0.0 2.5e-58 196.9 0.0 1.4 1 0 0 1 1 1 1 PRMT5 oligomerisation domain Adaptin_N PF01602.20 KKK14588.1 - 3.7e-85 286.5 4.5 4.5e-85 286.2 4.5 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.16 KKK14588.1 - 4.8e-45 152.4 0.0 1.2e-44 151.1 0.0 1.7 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.20 KKK14588.1 - 4.9e-17 62.2 0.0 1.2e-16 61.0 0.0 1.7 1 0 0 1 1 1 1 Adaptin C-terminal domain Cnd1 PF12717.7 KKK14588.1 - 0.0039 17.2 1.7 0.37 10.8 0.1 2.7 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 RIX1 PF08167.12 KKK14588.1 - 0.038 13.7 0.0 7.9 6.2 0.0 3.2 1 1 2 3 3 3 0 rRNA processing/ribosome biogenesis RTP1_C1 PF10363.9 KKK14588.1 - 0.098 12.8 0.2 1.3 9.3 0.1 2.8 3 0 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 Ala_racemase_N PF01168.20 KKK14589.1 - 5.3e-20 72.0 0.2 7.2e-20 71.6 0.2 1.2 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain FeThRed_B PF02943.15 KKK14590.1 - 0.048 13.7 3.3 0.065 13.2 3.3 1.2 1 0 0 1 1 1 0 Ferredoxin thioredoxin reductase catalytic beta chain TPR_1 PF00515.28 KKK14599.1 - 4.7e-06 26.2 0.0 0.00035 20.3 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 KKK14599.1 - 6.9e-06 25.6 0.0 0.003 17.2 0.0 3.1 3 0 0 3 3 3 1 TPR repeat TPR_19 PF14559.6 KKK14599.1 - 1.5e-05 25.4 0.0 5.7e-05 23.5 0.0 2.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 KKK14599.1 - 1.6e-05 25.3 2.3 0.0052 17.5 0.1 4.0 3 2 1 4 4 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KKK14599.1 - 4.6e-05 23.2 0.2 0.0022 18.0 0.0 3.7 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_17 PF13431.6 KKK14599.1 - 5.8e-05 23.2 0.1 0.00048 20.3 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 KKK14599.1 - 0.00046 20.2 0.0 0.014 15.6 0.0 3.2 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 KKK14599.1 - 0.0023 18.0 0.9 0.007 16.5 0.2 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 KKK14599.1 - 0.013 16.1 0.0 0.047 14.3 0.0 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_7 PF13176.6 KKK14599.1 - 0.015 15.3 0.0 1.3 9.2 0.0 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_20 PF14561.6 KKK14599.1 - 0.02 15.2 0.0 0.057 13.8 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_12 PF13424.6 KKK14599.1 - 0.027 14.7 0.1 0.17 12.2 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TniQ PF06527.11 KKK14599.1 - 0.051 14.3 0.1 0.37 11.5 0.0 2.1 1 1 0 2 2 2 0 TniQ HrpJ PF07201.11 KKK14599.1 - 0.083 13.2 0.1 0.38 11.0 0.0 2.1 3 0 0 3 3 3 0 HrpJ-like domain Sigma70_r4 PF04545.16 KKK14599.1 - 0.39 10.3 4.3 7.4 6.2 2.4 2.4 2 0 0 2 2 2 0 Sigma-70, region 4 Adaptin_N PF01602.20 KKK14600.1 - 4.2e-50 170.8 0.0 1e-49 169.5 0.0 1.6 1 1 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.6 KKK14600.1 - 6.4e-05 23.3 2.4 0.29 11.5 0.1 3.5 3 0 0 3 3 3 2 HEAT repeats Cnd1 PF12717.7 KKK14600.1 - 8.3e-05 22.7 0.2 0.019 15.0 0.0 2.4 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KKK14600.1 - 0.012 15.8 1.3 9.3 6.8 0.1 3.9 3 0 0 3 3 3 0 HEAT repeat HEAT_EZ PF13513.6 KKK14600.1 - 0.032 14.7 3.7 32 5.2 0.0 4.9 6 0 0 6 6 6 0 HEAT-like repeat Cnd3 PF12719.7 KKK14600.1 - 0.04 13.1 0.1 1.2 8.3 0.0 2.5 2 0 0 2 2 2 0 Nuclear condensing complex subunits, C-term domain RAMP4 PF06624.12 KKK14601.1 - 3.4e-17 62.2 7.0 1e-16 60.7 7.0 1.6 1 1 0 1 1 1 1 Ribosome associated membrane protein RAMP4 PIN_12 PF16289.5 KKK14602.1 - 1.3 9.4 7.8 2.2 8.7 7.8 1.3 1 0 0 1 1 1 0 PIN domain Asp-B-Hydro_N PF05279.11 KKK14602.1 - 3.8 7.5 21.4 7.8 6.5 21.4 1.4 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF4778 PF16008.5 KKK14602.1 - 7.2 6.6 13.2 39 4.2 9.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4778) DUF724 PF05266.14 KKK14602.1 - 8.7 6.1 16.3 14 5.5 16.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) APH PF01636.23 KKK14603.1 - 1.8e-12 47.7 0.0 4.3e-12 46.5 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KKK14603.1 - 0.00058 19.5 0.0 0.00079 19.1 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF1289 PF06945.13 KKK14603.1 - 0.21 11.4 0.3 0.72 9.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1289) Utp21 PF04192.12 KKK14604.1 - 2.1e-68 230.3 0.0 3.3e-68 229.7 0.0 1.2 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.32 KKK14604.1 - 6e-18 64.9 33.4 6.9e-05 23.5 0.4 10.9 11 0 0 11 11 11 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKK14604.1 - 4.2e-17 62.2 0.1 0.019 15.3 0.0 7.1 2 2 5 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain PALB2_WD40 PF16756.5 KKK14604.1 - 0.0012 17.8 0.2 0.025 13.5 0.0 2.5 3 0 0 3 3 3 1 Partner and localizer of BRCA2 WD40 domain Cytochrom_D1 PF02239.16 KKK14604.1 - 0.18 10.3 0.2 0.56 8.7 0.0 1.9 2 0 0 2 2 2 0 Cytochrome D1 heme domain XPG_I_2 PF12813.7 KKK14605.1 - 4.5e-77 258.9 0.0 6.4e-77 258.4 0.0 1.2 1 0 0 1 1 1 1 XPG domain containing DAGAT PF03982.13 KKK14606.1 - 1.1e-86 290.4 0.0 1.4e-86 290.1 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase G-patch PF01585.23 KKK14607.1 - 1.8e-05 24.5 0.0 0.00025 20.9 0.0 2.5 1 1 0 1 1 1 1 G-patch domain DUF936 PF06075.12 KKK14607.1 - 0.042 12.8 27.6 0.05 12.5 27.6 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) SRP-alpha_N PF04086.13 KKK14607.1 - 0.35 10.7 34.8 0.48 10.3 34.8 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Pox_L3_FP4 PF03339.14 KKK14607.1 - 0.79 8.7 6.1 1.3 8.0 6.1 1.2 1 0 0 1 1 1 0 Poxvirus L3/FP4 protein G-patch_2 PF12656.7 KKK14607.1 - 2.1 8.5 0.0 2.1 8.5 0.0 3.5 2 1 0 2 2 2 0 G-patch domain Syja_N PF02383.18 KKK14608.1 - 2.2e-72 244.1 0.0 2.9e-72 243.7 0.0 1.1 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.23 KKK14608.1 - 8.5e-10 38.5 0.2 1.6e-09 37.6 0.2 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Herpes_ICP4_N PF03584.15 KKK14608.1 - 0.13 12.1 0.0 0.25 11.1 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus ICP4-like protein N-terminal region dCMP_cyt_deam_1 PF00383.23 KKK14610.1 - 9.4e-12 44.7 0.4 1.2e-11 44.4 0.4 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.12 KKK14610.1 - 1.5e-08 34.9 0.7 1.8e-08 34.6 0.7 1.0 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Peptidase_M42 PF05343.14 KKK14610.1 - 0.042 12.9 0.1 0.045 12.8 0.1 1.1 1 0 0 1 1 1 0 M42 glutamyl aminopeptidase LmjF365940-deam PF14421.6 KKK14610.1 - 0.085 12.5 0.1 0.085 12.5 0.1 1.3 1 0 0 1 1 1 0 A distinct subfamily of CDD/CDA-like deaminases BTB PF00651.31 KKK14612.1 - 0.14 12.4 0.0 0.63 10.3 0.0 2.0 2 0 0 2 2 2 0 BTB/POZ domain tRNA-synt_2b PF00587.25 KKK14613.1 - 1.9e-20 73.6 0.0 3e-20 72.9 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 KKK14613.1 - 5.3e-10 39.5 2.9 8.9e-10 38.8 2.9 1.3 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain FAM76 PF16046.5 KKK14613.1 - 0.0071 15.7 2.8 0.011 15.1 2.8 1.2 1 0 0 1 1 1 1 FAM76 protein GOLGA2L5 PF15070.6 KKK14613.1 - 0.019 13.6 4.6 0.027 13.1 4.6 1.1 1 0 0 1 1 1 0 Putative golgin subfamily A member 2-like protein 5 HOOK PF05622.12 KKK14613.1 - 0.022 12.9 3.1 0.03 12.5 3.1 1.1 1 0 0 1 1 1 0 HOOK protein ING PF12998.7 KKK14613.1 - 0.024 15.2 4.7 0.044 14.4 4.7 1.3 1 0 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding HAUS-augmin3 PF14932.6 KKK14613.1 - 0.036 13.6 4.0 0.068 12.7 4.0 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 CENP-F_leu_zip PF10473.9 KKK14613.1 - 0.067 13.2 6.9 0.13 12.3 6.0 1.8 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Pil1 PF13805.6 KKK14613.1 - 0.099 12.1 4.5 0.16 11.5 4.5 1.2 1 0 0 1 1 1 0 Eisosome component PIL1 FUSC PF04632.12 KKK14613.1 - 0.14 10.7 1.0 0.19 10.2 1.0 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family BLOC1_2 PF10046.9 KKK14613.1 - 0.16 12.3 2.0 0.22 11.8 0.1 1.9 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Spc7 PF08317.11 KKK14613.1 - 0.19 10.6 7.2 0.28 10.0 7.2 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein FapA PF03961.13 KKK14613.1 - 0.3 9.6 3.0 0.46 9.0 3.0 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF2968 PF11180.8 KKK14613.1 - 0.36 10.4 9.6 0.58 9.8 9.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) DUF3818 PF12825.7 KKK14613.1 - 0.38 9.7 1.7 0.57 9.2 1.7 1.1 1 0 0 1 1 1 0 Domain of unknown function in PX-proteins (DUF3818) DUF3584 PF12128.8 KKK14613.1 - 0.4 8.1 5.9 0.55 7.7 5.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) TMPIT PF07851.13 KKK14613.1 - 0.48 9.6 2.6 0.74 9.0 2.6 1.2 1 0 0 1 1 1 0 TMPIT-like protein TMF_DNA_bd PF12329.8 KKK14613.1 - 1.2 9.2 9.7 3.9 7.6 8.2 2.2 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF4140 PF13600.6 KKK14613.1 - 2.7 8.5 10.0 11 6.5 0.3 2.5 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) ERM PF00769.19 KKK14613.1 - 4.9 6.9 11.6 0.36 10.6 6.8 1.5 2 0 0 2 2 2 0 Ezrin/radixin/moesin family AIP3 PF03915.13 KKK14613.1 - 5.1 6.1 7.6 1.6 7.8 3.0 1.9 2 0 0 2 2 2 0 Actin interacting protein 3 DivIC PF04977.15 KKK14613.1 - 5.2 6.9 10.2 3.5 7.5 1.6 2.5 1 1 1 2 2 2 0 Septum formation initiator YlqD PF11068.8 KKK14613.1 - 6.7 7.1 9.4 13 6.1 9.4 1.4 1 0 0 1 1 1 0 YlqD protein Pkinase PF00069.25 KKK14614.1 - 1.8e-66 224.2 0.0 2.4e-66 223.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK14614.1 - 2.1e-31 109.1 0.0 1.6e-30 106.3 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KKK14614.1 - 0.0017 17.4 0.1 0.0025 16.8 0.1 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KKK14614.1 - 0.0019 17.6 0.0 0.0033 16.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 KKK14614.1 - 0.0081 15.8 0.1 0.1 12.2 0.0 2.1 1 1 1 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 KKK14614.1 - 0.011 15.0 0.0 0.037 13.4 0.0 1.9 2 0 0 2 2 2 0 Kinase-like RIO1 PF01163.22 KKK14614.1 - 0.069 12.7 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Fungal_trans_2 PF11951.8 KKK14615.1 - 2.7e-31 108.8 0.3 7.3e-31 107.3 0.3 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK14615.1 - 4.3e-06 26.7 6.7 8e-06 25.9 6.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PBP1_TM PF14812.6 KKK14615.1 - 4.1 7.8 7.2 9.2 6.7 7.2 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal NOA36 PF06524.12 KKK14615.1 - 9.5 5.4 7.3 17 4.6 7.3 1.3 1 0 0 1 1 1 0 NOA36 protein Glyco_hydro_1 PF00232.18 KKK14616.1 - 3.9e-143 477.1 0.9 5.4e-143 476.7 0.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Glyco_hyd_65N_2 PF14498.6 KKK14616.1 - 2.1e-58 198.0 0.0 3e-58 197.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Sugar_tr PF00083.24 KKK14617.1 - 2e-41 142.3 9.8 2.3e-41 142.1 9.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKK14617.1 - 3.4e-14 52.6 14.9 4.5e-14 52.1 14.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily CBM_4_9 PF02018.17 KKK14620.1 - 2e-09 37.8 4.0 5.7e-09 36.4 4.0 1.8 1 0 0 1 1 1 1 Carbohydrate binding domain Lipase_GDSL_2 PF13472.6 KKK14621.1 - 1.1e-11 45.5 1.9 3e-11 44.0 1.9 1.8 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KKK14621.1 - 5.4e-08 33.1 0.0 7.5e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.6 KKK14621.1 - 0.12 12.5 0.3 0.23 11.6 0.0 1.5 2 0 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family CMD PF02627.20 KKK14622.1 - 0.024 14.7 7.1 0.56 10.3 0.2 3.3 3 2 0 3 3 3 0 Carboxymuconolactone decarboxylase family MFS_1 PF07690.16 KKK14623.1 - 2.8e-28 98.9 48.4 1.7e-24 86.4 48.8 3.6 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KKK14623.1 - 3e-16 59.0 28.1 7.4e-15 54.4 28.1 2.1 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) WD40 PF00400.32 KKK14624.1 - 1.9e-22 79.1 4.4 4.4e-06 27.3 0.1 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKK14624.1 - 3e-07 30.6 0.1 0.14 12.5 0.0 4.1 2 2 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 KKK14624.1 - 7.6e-05 21.6 0.0 0.78 8.4 0.0 3.2 1 1 2 3 3 3 3 Nup133 N terminal like Nup160 PF11715.8 KKK14624.1 - 0.00029 19.6 0.0 0.15 10.6 0.0 2.8 3 0 0 3 3 3 2 Nucleoporin Nup120/160 YbaB_DNA_bd PF02575.16 KKK14624.1 - 0.077 13.2 0.0 14 6.0 0.0 2.4 2 0 0 2 2 2 0 YbaB/EbfC DNA-binding family SGL PF08450.12 KKK14624.1 - 0.13 11.8 1.5 5.9 6.4 0.0 3.1 1 1 2 3 3 3 0 SMP-30/Gluconolactonase/LRE-like region LSM14 PF12701.7 KKK14625.1 - 5.5e-28 96.9 0.0 9.4e-28 96.1 0.0 1.4 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.10 KKK14625.1 - 1.9e-21 76.9 4.0 2.1e-21 76.8 1.9 2.0 2 0 0 2 2 2 1 FDF domain SM-ATX PF14438.6 KKK14625.1 - 1.8e-05 24.8 0.0 3.4e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM PF01423.22 KKK14625.1 - 0.26 11.0 0.0 0.38 10.5 0.0 1.3 1 0 0 1 1 1 0 LSM domain Carn_acyltransf PF00755.20 KKK14626.1 - 3.7e-209 696.2 0.0 4.5e-209 695.9 0.0 1.1 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase CAP PF00188.26 KKK14627.1 - 4.1e-18 66.4 1.4 4.1e-18 66.4 1.4 2.1 2 0 0 2 2 2 1 Cysteine-rich secretory protein family SWI-SNF_Ssr4 PF08549.10 KKK14627.1 - 1.7 7.2 22.0 2.1 6.9 22.0 1.0 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) Macoilin PF09726.9 KKK14627.1 - 3.3 6.2 12.6 3.9 5.9 12.6 1.1 1 0 0 1 1 1 0 Macoilin family Thioredox_DsbH PF03190.15 KKK14628.1 - 1.4e-72 243.0 0.0 3.9e-72 241.5 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function, DUF255 Thioredoxin_7 PF13899.6 KKK14628.1 - 1.8e-05 24.8 0.0 3.4e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like Glyco_hydro_9 PF00759.19 KKK14628.1 - 0.0049 16.4 0.0 0.0083 15.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 Glyco_hydro_88 PF07470.13 KKK14628.1 - 0.04 13.0 0.1 1.2 8.1 0.0 2.8 2 1 1 3 3 3 0 Glycosyl Hydrolase Family 88 DNA_primase_lrg PF04104.14 KKK14629.1 - 1e-86 290.6 0.0 1.5e-86 290.1 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit Sec23_trunk PF04811.15 KKK14630.1 - 9e-81 271.0 0.0 1.3e-80 270.5 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 KKK14630.1 - 7.4e-30 103.6 0.1 1.5e-29 102.5 0.1 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 KKK14630.1 - 5.4e-25 87.2 0.1 1.5e-24 85.8 0.1 1.8 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 KKK14630.1 - 6.7e-15 54.9 4.0 1.3e-14 53.9 4.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 KKK14630.1 - 4.3e-12 45.8 0.0 1.3e-11 44.3 0.0 1.9 2 0 0 2 2 2 1 Gelsolin repeat Vps36-NZF-N PF16988.5 KKK14630.1 - 0.012 15.0 1.3 0.019 14.3 0.2 1.9 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Ribosomal_L11_N PF03946.14 KKK14631.1 - 1e-24 86.1 0.2 2e-24 85.2 0.2 1.5 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 KKK14631.1 - 3.2e-15 56.4 0.2 4.8e-15 55.8 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain ADK PF00406.22 KKK14632.1 - 8.7e-35 120.1 0.0 2.1e-34 118.8 0.0 1.5 1 1 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.14 KKK14632.1 - 3.6e-15 55.6 0.0 6e-15 54.9 0.0 1.4 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_17 PF13207.6 KKK14632.1 - 3.4e-13 50.2 0.0 1.3e-12 48.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KKK14632.1 - 1.7e-05 25.4 0.0 3.6e-05 24.3 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KKK14632.1 - 0.01 16.0 0.0 0.029 14.5 0.0 1.8 2 1 0 2 2 2 0 AAA domain MeaB PF03308.16 KKK14632.1 - 0.096 11.6 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_22 PF13401.6 KKK14632.1 - 0.15 12.4 0.0 0.25 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KKK14632.1 - 0.17 12.1 0.0 0.32 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain SNase PF00565.17 KKK14633.1 - 3.7e-19 69.2 0.0 4.8e-19 68.8 0.0 1.1 1 0 0 1 1 1 1 Staphylococcal nuclease homologue MAP65_ASE1 PF03999.12 KKK14634.1 - 3.7e-55 187.8 21.4 9.8e-29 100.5 3.0 2.3 1 1 1 2 2 2 2 Microtubule associated protein (MAP65/ASE1 family) ApoLp-III PF07464.11 KKK14634.1 - 0.0013 18.9 1.5 0.004 17.3 0.9 2.1 1 1 0 1 1 1 1 Apolipophorin-III precursor (apoLp-III) Baculo_PEP_C PF04513.12 KKK14634.1 - 0.25 11.4 4.8 0.71 9.9 2.0 3.1 5 0 0 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus MCU PF04678.13 KKK14634.1 - 0.59 10.2 0.0 0.59 10.2 0.0 2.7 3 1 0 3 3 3 0 Mitochondrial calcium uniporter Fzo_mitofusin PF04799.13 KKK14634.1 - 8.3 5.9 6.7 1.7 8.2 2.0 2.2 2 0 0 2 2 2 0 fzo-like conserved region JAB PF01398.21 KKK14635.1 - 4.4e-29 100.8 0.0 8.1e-29 100.0 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease CSN5_C PF18323.1 KKK14635.1 - 8.4e-22 77.9 0.1 1.7e-21 76.9 0.1 1.5 1 0 0 1 1 1 1 Cop9 signalosome subunit 5 C-terminal domain Prok-JAB PF14464.6 KKK14635.1 - 0.0004 20.1 0.0 0.00078 19.2 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain RasGEF PF00617.19 KKK14636.1 - 1.2e-59 201.5 0.1 2.1e-59 200.7 0.1 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 KKK14636.1 - 1.9e-29 102.0 0.1 4.2e-29 100.9 0.1 1.6 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_1 PF00018.28 KKK14636.1 - 5.4e-16 57.9 0.1 1.1e-15 57.0 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KKK14636.1 - 1.5e-13 50.4 0.1 4.4e-13 48.9 0.1 1.9 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KKK14636.1 - 1.7e-11 43.6 0.1 4e-11 42.4 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain WW PF00397.26 KKK14636.1 - 0.008 16.3 0.0 0.016 15.3 0.0 1.5 1 0 0 1 1 1 1 WW domain COesterase PF00135.28 KKK14643.1 - 1.3e-36 126.5 0.0 1.7e-36 126.2 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KKK14643.1 - 0.12 12.2 0.0 0.91 9.3 0.0 2.2 3 0 0 3 3 3 0 alpha/beta hydrolase fold CPSase_L_D2 PF02786.17 KKK14644.1 - 1.9e-81 272.6 0.1 3.1e-81 271.9 0.1 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.18 KKK14644.1 - 2.7e-69 232.9 0.0 4.3e-69 232.2 0.0 1.4 1 0 0 1 1 1 1 Conserved carboxylase domain Biotin_carb_N PF00289.22 KKK14644.1 - 5.5e-39 133.1 0.0 1.1e-38 132.1 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 KKK14644.1 - 1.2e-30 105.8 0.0 3.7e-30 104.2 0.0 1.9 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.19 KKK14644.1 - 1.1e-26 94.0 0.0 2.3e-26 93.0 0.0 1.5 1 0 0 1 1 1 1 HMGL-like Biotin_lipoyl PF00364.22 KKK14644.1 - 1.4e-18 66.5 2.8 1.4e-18 66.5 2.8 2.2 2 0 0 2 2 2 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 KKK14644.1 - 4.9e-10 39.3 0.0 9.6e-10 38.3 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.6 KKK14644.1 - 6.7e-10 38.6 2.9 1.5e-05 24.7 0.2 3.1 2 1 1 3 3 3 2 Biotin-lipoyl like ATP-grasp PF02222.22 KKK14644.1 - 8.7e-08 31.9 0.0 1.8e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 KKK14644.1 - 6.1e-05 23.1 0.0 0.00016 21.8 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain HlyD_3 PF13437.6 KKK14644.1 - 0.00014 22.5 0.5 0.44 11.3 0.1 3.5 3 0 0 3 3 3 1 HlyD family secretion protein RimK PF08443.11 KKK14644.1 - 0.00045 19.9 0.0 0.002 17.8 0.0 2.0 1 1 0 1 1 1 1 RimK-like ATP-grasp domain HlyD_D23 PF16576.5 KKK14644.1 - 0.00054 19.2 0.2 0.036 13.3 0.1 2.3 1 1 1 2 2 2 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion ATP-grasp_4 PF13535.6 KKK14644.1 - 0.01 15.4 0.0 0.025 14.2 0.0 1.7 1 0 0 1 1 1 0 ATP-grasp domain DUF2118 PF09891.9 KKK14644.1 - 0.037 14.0 0.2 0.1 12.6 0.2 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2118) GCV_H PF01597.19 KKK14644.1 - 0.12 12.3 1.1 0.4 10.6 0.5 2.1 1 1 1 2 2 2 0 Glycine cleavage H-protein NQRA PF05896.11 KKK14644.1 - 0.12 11.7 0.2 0.22 10.9 0.2 1.3 1 0 0 1 1 1 0 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) RnfC_N PF13375.6 KKK14644.1 - 0.27 11.2 2.3 1.8 8.6 2.0 2.3 1 1 0 1 1 1 0 RnfC Barrel sandwich hybrid domain DUF3040 PF11239.8 KKK14646.1 - 0.018 15.3 0.1 0.04 14.2 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3040) Serinc PF03348.15 KKK14646.1 - 0.097 11.6 1.7 0.11 11.3 1.7 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) LAX PF15681.5 KKK14646.1 - 0.14 11.0 0.7 0.17 10.7 0.7 1.1 1 0 0 1 1 1 0 Lymphocyte activation family X DUF872 PF05915.12 KKK14646.1 - 0.17 12.0 0.1 0.19 11.9 0.1 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF872) Sarcoglycan_1 PF04790.13 KKK14646.1 - 0.4 10.0 2.8 0.52 9.6 2.8 1.1 1 0 0 1 1 1 0 Sarcoglycan complex subunit protein TMEM190 PF15431.6 KKK14646.1 - 0.86 9.8 3.8 1 9.5 3.6 1.3 1 1 0 1 1 1 0 Transmembrane protein 190 DUF4381 PF14316.6 KKK14646.1 - 2.3 8.4 7.6 1.2 9.3 5.7 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4381) Amidase PF01425.21 KKK14647.1 - 3.1e-81 273.6 0.0 5.2e-81 272.9 0.0 1.3 1 1 0 1 1 1 1 Amidase Fungal_trans_2 PF11951.8 KKK14648.1 - 1.4e-07 30.7 0.0 3.3e-07 29.5 0.0 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain AT_hook PF02178.19 KKK14649.1 - 0.0091 15.8 37.7 0.061 13.2 2.0 4.7 4 0 0 4 4 4 3 AT hook motif HMGL-like PF00682.19 KKK14650.1 - 3.9e-23 82.4 0.0 1.9e-18 67.0 0.0 2.1 2 0 0 2 2 2 2 HMGL-like AflR PF08493.10 KKK14651.1 - 1.2e-62 212.0 11.9 2e-62 211.3 11.9 1.3 1 0 0 1 1 1 1 Aflatoxin regulatory protein Zn_clus PF00172.18 KKK14651.1 - 1.1e-08 35.0 11.1 2.1e-08 34.1 11.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Spem1 PF15670.5 KKK14651.1 - 0.27 10.8 2.7 0.49 9.9 2.7 1.3 1 0 0 1 1 1 0 Spermatid maturation protein 1 DUF4267 PF14087.6 KKK14652.1 - 9.5e-27 93.3 0.8 1.6e-26 92.6 0.8 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) 2OG-FeII_Oxy_2 PF13532.6 KKK14652.1 - 3.5e-18 66.5 0.2 1.3e-12 48.3 0.0 2.2 2 0 0 2 2 2 2 2OG-Fe(II) oxygenase superfamily zf-GRF PF06839.12 KKK14652.1 - 2.1e-06 27.7 5.7 3.7e-06 26.9 5.7 1.4 1 0 0 1 1 1 1 GRF zinc finger UT PF03253.14 KKK14652.1 - 0.045 12.9 0.1 0.066 12.3 0.1 1.2 1 0 0 1 1 1 0 Urea transporter DUF3425 PF11905.8 KKK14653.1 - 1.1e-21 77.1 1.1 2e-21 76.3 1.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) SlyX PF04102.12 KKK14653.1 - 0.0027 18.3 1.1 0.0065 17.1 1.1 1.7 1 0 0 1 1 1 1 SlyX NPV_P10 PF05531.12 KKK14653.1 - 0.0039 17.6 1.1 0.0075 16.7 1.1 1.4 1 0 0 1 1 1 1 Nucleopolyhedrovirus P10 protein CALCOCO1 PF07888.11 KKK14653.1 - 0.014 14.3 7.9 0.018 13.9 7.9 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Exonuc_VII_L PF02601.15 KKK14653.1 - 0.022 14.3 5.1 0.034 13.7 5.1 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit BLOC1_2 PF10046.9 KKK14653.1 - 0.067 13.5 2.3 0.12 12.7 2.3 1.3 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FAM86 PF14904.6 KKK14653.1 - 0.069 13.2 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function Fmp27_WPPW PF10359.9 KKK14653.1 - 0.1 11.4 5.0 0.15 10.9 5.0 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DUF1465 PF07323.12 KKK14653.1 - 0.1 12.4 5.1 0.16 11.8 5.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1465) Macoilin PF09726.9 KKK14653.1 - 0.13 10.8 6.1 0.17 10.4 6.1 1.1 1 0 0 1 1 1 0 Macoilin family Jnk-SapK_ap_N PF09744.9 KKK14653.1 - 0.14 12.4 7.6 0.2 11.8 7.6 1.2 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Fib_alpha PF08702.10 KKK14653.1 - 0.14 12.3 4.7 0.28 11.4 4.7 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family LCD1 PF09798.9 KKK14653.1 - 0.14 10.6 3.1 0.21 10.1 3.1 1.2 1 0 0 1 1 1 0 DNA damage checkpoint protein DUF3573 PF12097.8 KKK14653.1 - 0.28 10.0 0.3 0.36 9.6 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) End3 PF12761.7 KKK14653.1 - 0.36 11.0 7.7 0.51 10.5 7.7 1.2 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 V_ATPase_I PF01496.19 KKK14653.1 - 0.45 8.4 1.8 0.58 8.0 1.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FlaC_arch PF05377.11 KKK14653.1 - 0.55 10.7 2.2 1.1 9.7 2.2 1.4 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) DUF1664 PF07889.12 KKK14653.1 - 0.65 10.0 3.2 1.1 9.3 3.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Prominin PF05478.11 KKK14653.1 - 1.1 7.1 3.6 1.5 6.6 3.6 1.1 1 0 0 1 1 1 0 Prominin DUF641 PF04859.12 KKK14653.1 - 1.8 8.9 7.6 2.8 8.3 7.6 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) Phlebovirus_NSM PF07246.11 KKK14653.1 - 2.1 7.7 5.7 3 7.1 5.7 1.1 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M bZIP_1 PF00170.21 KKK14654.1 - 5.3e-10 39.2 15.9 8.9e-10 38.5 15.9 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KKK14654.1 - 2e-06 27.7 12.2 4e-06 26.8 12.2 1.5 1 0 0 1 1 1 1 Basic region leucine zipper FPP PF05911.11 KKK14654.1 - 0.0012 17.2 4.7 0.0013 17.0 4.7 1.1 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil bZIP_Maf PF03131.17 KKK14654.1 - 0.016 15.7 10.6 0.031 14.8 10.6 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor DivIC PF04977.15 KKK14654.1 - 0.14 12.0 4.2 0.3 10.9 4.2 1.5 1 0 0 1 1 1 0 Septum formation initiator SR-25 PF10500.9 KKK14654.1 - 0.28 10.7 10.7 0.41 10.2 10.7 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein LCD1 PF09798.9 KKK14654.1 - 0.38 9.2 4.1 0.49 8.9 4.1 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein FapA PF03961.13 KKK14654.1 - 0.56 8.7 3.1 0.74 8.3 3.1 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Occludin_ELL PF07303.13 KKK14654.1 - 1.2 9.8 7.7 2.3 9.0 7.7 1.3 1 0 0 1 1 1 0 Occludin homology domain M20_dimer PF07687.14 KKK14655.1 - 3.9e-09 36.4 0.1 1.1e-08 35.0 0.0 1.7 2 0 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M20 PF01546.28 KKK14655.1 - 1.5e-08 34.6 0.2 2.7e-08 33.8 0.2 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 PhyH PF05721.13 KKK14656.1 - 1.1e-11 45.5 0.0 1.7e-11 44.8 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.12 KKK14656.1 - 9.4e-09 34.5 0.1 0.017 13.9 0.0 3.0 3 0 0 3 3 3 3 Protein of unknown function (DUF1479) DPRP PF04244.13 KKK14656.1 - 0.085 12.7 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 Deoxyribodipyrimidine photo-lyase-related protein MFS_1 PF07690.16 KKK14657.1 - 7e-29 100.9 37.0 7e-29 100.9 37.0 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily 2OG-FeII_Oxy PF03171.20 KKK14658.1 - 3.1e-17 62.9 0.0 4.3e-17 62.4 0.0 1.4 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 KKK14658.1 - 3.4e-12 47.2 0.0 1.2e-11 45.4 0.0 2.0 1 1 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Fringe PF02434.16 KKK14659.1 - 9.3e-10 38.4 0.2 1.1e-08 34.9 0.2 2.1 1 1 0 1 1 1 1 Fringe-like PAN_1 PF00024.26 KKK14659.1 - 0.0064 16.4 0.1 0.013 15.5 0.1 1.4 1 0 0 1 1 1 1 PAN domain PAN_2 PF08276.11 KKK14659.1 - 0.0065 16.6 0.1 0.013 15.6 0.1 1.4 1 0 0 1 1 1 1 PAN-like domain PAN_4 PF14295.6 KKK14659.1 - 0.058 13.3 0.6 0.16 11.9 0.6 1.7 1 0 0 1 1 1 0 PAN domain Glyco_transf_34 PF05637.12 KKK14659.1 - 0.48 10.1 2.0 0.9 9.2 2.0 1.3 1 0 0 1 1 1 0 galactosyl transferase GMA12/MNN10 family Fungal_trans_2 PF11951.8 KKK14660.1 - 1.6e-53 181.9 1.1 2.1e-53 181.5 1.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK14660.1 - 5.8e-07 29.5 38.1 2.6e-05 24.2 9.5 3.1 3 0 0 3 3 3 2 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 KKK14661.1 - 5.7e-29 101.1 19.6 5.7e-29 101.1 19.6 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Peptidase_A8 PF01252.18 KKK14661.1 - 1.5 9.0 8.3 1.3 9.2 1.8 3.1 3 1 0 3 3 3 0 Signal peptidase (SPase) II Arginase PF00491.21 KKK14662.1 - 9.7e-09 35.1 0.0 1.1e-08 34.9 0.0 1.1 1 0 0 1 1 1 1 Arginase family DUF4188 PF13826.6 KKK14663.1 - 1.3e-31 109.4 0.3 1.7e-31 108.9 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4188) Dabb PF07876.12 KKK14663.1 - 0.0039 17.8 0.0 0.0065 17.1 0.0 1.3 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain ANF_receptor PF01094.28 KKK14663.1 - 0.05 12.7 0.0 0.068 12.3 0.0 1.2 1 0 0 1 1 1 0 Receptor family ligand binding region DUF3328 PF11807.8 KKK14664.1 - 6.7e-58 196.1 0.2 7.9e-58 195.8 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Dynamin_N PF00350.23 KKK14665.1 - 4.9e-36 124.3 0.0 8.1e-36 123.6 0.0 1.4 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 KKK14665.1 - 1.6e-25 89.9 0.1 2.7e-25 89.2 0.1 1.4 1 0 0 1 1 1 1 Dynamin central region MMR_HSR1 PF01926.23 KKK14665.1 - 2e-05 24.7 0.0 6.2e-05 23.1 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_15 PF13175.6 KKK14665.1 - 0.11 12.2 0.3 0.24 11.1 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain AAA_21 PF13304.6 KKK14665.1 - 0.12 12.1 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KKK14665.1 - 0.16 11.7 0.0 0.37 10.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain MnmE_helical PF12631.7 KKK14665.1 - 0.49 10.5 2.3 3.2 7.9 2.3 2.3 1 1 0 1 1 1 0 MnmE helical domain HSP70 PF00012.20 KKK14666.1 - 2.5e-76 257.2 0.0 9.3e-76 255.3 0.0 1.7 1 1 0 1 1 1 1 Hsp70 protein UPRTase PF14681.6 KKK14667.1 - 2.4e-66 223.1 0.0 3e-66 222.8 0.0 1.1 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 KKK14667.1 - 0.00084 18.9 0.1 0.0011 18.5 0.1 1.4 1 1 0 1 1 1 1 Phosphoribosyl transferase domain Hemerythrin PF01814.23 KKK14668.1 - 0.00037 21.1 0.0 0.89 10.2 0.0 2.3 1 1 1 2 2 2 2 Hemerythrin HHE cation binding domain CDC45 PF02724.14 KKK14669.1 - 3.3e-234 778.9 14.0 5.7e-215 715.4 0.0 3.1 2 1 1 3 3 2 2 CDC45-like protein Cwf_Cwc_15 PF04889.12 KKK14669.1 - 0.0043 16.8 8.3 0.0043 16.8 8.3 2.5 2 0 0 2 2 2 1 Cwf15/Cwc15 cell cycle control protein BUD22 PF09073.10 KKK14669.1 - 0.007 15.8 34.9 0.11 11.8 15.6 2.2 2 0 0 2 2 2 2 BUD22 RNA_pol_3_Rpc31 PF11705.8 KKK14669.1 - 0.23 11.7 28.2 1.7 8.9 14.4 3.6 3 0 0 3 3 3 0 DNA-directed RNA polymerase III subunit Rpc31 Nop14 PF04147.12 KKK14669.1 - 0.58 8.3 29.1 0.66 8.1 11.8 2.1 2 0 0 2 2 2 0 Nop14-like family DUF2052 PF09747.9 KKK14669.1 - 4 7.5 26.0 1.4 9.0 10.9 2.5 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) SDA1 PF05285.12 KKK14669.1 - 5.9 6.2 32.9 6 6.2 13.7 2.3 2 0 0 2 2 2 0 SDA1 DUF572 PF04502.13 KKK14669.1 - 6 6.4 25.1 3.1 7.3 6.1 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF572) DDHD PF02862.17 KKK14669.1 - 6.6 6.8 7.9 1.1 9.4 1.6 2.2 2 0 0 2 2 2 0 DDHD domain SPX PF03105.19 KKK14669.1 - 7.9 6.3 29.4 4.1 7.2 14.6 2.4 2 0 0 2 2 2 0 SPX domain FAM60A PF15396.6 KKK14669.1 - 8.8 6.3 17.5 0.17 11.9 5.6 2.2 2 0 0 2 2 2 0 Protein Family FAM60A zf-H2C2_2 PF13465.6 KKK14670.1 - 1.4e-05 25.3 27.8 6.1e-05 23.3 3.3 4.7 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2 PF00096.26 KKK14670.1 - 2.1e-05 24.7 14.0 0.00081 19.7 4.5 3.3 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KKK14670.1 - 0.035 14.9 20.3 0.056 14.3 3.0 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KKK14670.1 - 0.037 14.3 0.2 0.13 12.6 0.2 1.9 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 KKK14670.1 - 0.066 13.8 1.3 0.23 12.1 0.1 2.4 1 1 1 2 2 2 0 FOXP coiled-coil domain zf-C2H2_6 PF13912.6 KKK14670.1 - 0.12 12.4 0.8 9.6 6.3 0.2 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger LSM PF01423.22 KKK14671.1 - 1.3e-14 53.6 0.1 2e-14 53.0 0.1 1.3 1 0 0 1 1 1 1 LSM domain zf-LYAR PF08790.11 KKK14672.1 - 0.12 12.3 0.3 0.24 11.3 0.3 1.5 1 0 0 1 1 1 0 LYAR-type C2HC zinc finger Asp PF00026.23 KKK14673.1 - 4.4e-71 239.9 6.1 4.4e-71 239.9 6.1 1.9 2 0 0 2 2 2 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KKK14673.1 - 9.2e-15 55.3 5.7 1e-09 38.9 0.5 3.2 3 1 1 4 4 4 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KKK14673.1 - 2.3e-06 28.1 0.1 0.095 13.4 0.0 2.9 2 0 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 KKK14673.1 - 0.0066 17.0 0.0 7.6 7.2 0.0 2.9 2 1 0 2 2 2 2 gag-polyprotein putative aspartyl protease TAXi_C PF14541.6 KKK14673.1 - 0.018 14.8 0.0 0.17 11.7 0.0 2.2 2 0 0 2 2 2 0 Xylanase inhibitor C-terminal SAP PF02037.27 KKK14674.1 - 1.9e-08 33.9 0.4 4.1e-08 32.8 0.0 1.8 2 0 0 2 2 2 1 SAP domain Ribosomal_S7e PF01251.18 KKK14674.1 - 0.069 12.9 0.0 0.15 11.8 0.0 1.5 2 0 0 2 2 2 0 Ribosomal protein S7e Rad52_Rad22 PF04098.15 KKK14675.1 - 4.8e-59 198.7 0.0 7.1e-59 198.1 0.0 1.2 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein UBA PF00627.31 KKK14676.1 - 3.3e-06 26.9 0.0 6.6e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain UBX PF00789.20 KKK14676.1 - 0.0015 18.7 0.2 0.0067 16.6 0.0 2.2 3 0 0 3 3 2 1 UBX domain CDC27 PF09507.10 KKK14676.1 - 0.015 14.7 22.3 0.017 14.5 22.3 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 zf-C2H2_2 PF12756.7 KKK14676.1 - 0.038 14.3 0.2 0.087 13.2 0.2 1.6 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) Utp11 PF03998.13 KKK14676.1 - 0.11 12.4 21.9 0.15 12.0 21.9 1.1 1 0 0 1 1 1 0 Utp11 protein GATA PF00320.27 KKK14676.1 - 0.16 11.6 0.0 0.28 10.8 0.0 1.4 1 0 0 1 1 1 0 GATA zinc finger zf-C2HE PF16278.5 KKK14676.1 - 0.28 11.6 0.1 0.28 11.6 0.1 2.9 2 1 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger CpXC PF14353.6 KKK14676.1 - 1.6 8.8 7.7 6.1 6.9 7.7 2.0 1 1 0 1 1 1 0 CpXC protein DUF4551 PF15087.6 KKK14676.1 - 1.9 7.2 10.4 2.3 6.9 10.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) V_ATPase_I PF01496.19 KKK14676.1 - 3.4 5.5 6.6 3.4 5.5 6.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CENP-N PF05238.13 KKK14676.1 - 4.4 6.5 12.5 6.2 6.0 12.5 1.2 1 0 0 1 1 1 0 Kinetochore protein CHL4 like ArfGap PF01412.18 KKK14676.1 - 4.6 7.3 8.8 0.2 11.7 1.9 2.1 2 1 1 3 3 3 0 Putative GTPase activating protein for Arf LMBR1 PF04791.16 KKK14676.1 - 4.9 5.9 4.5 5.2 5.9 4.5 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Rtf2 PF04641.12 KKK14676.1 - 5.2 6.4 20.5 7.9 5.8 20.5 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger FapA PF03961.13 KKK14676.1 - 6 5.4 14.4 8.6 4.8 14.4 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A GREB1 PF15782.5 KKK14676.1 - 7.6 3.5 9.9 8.6 3.3 9.9 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SOBP PF15279.6 KKK14676.1 - 8.3 6.9 8.6 10 6.6 8.6 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Motile_Sperm PF00635.26 KKK14677.1 - 2.6e-23 81.9 0.6 5.8e-23 80.8 0.5 1.6 1 1 1 2 2 2 1 MSP (Major sperm protein) domain ASH PF15780.5 KKK14677.1 - 0.023 14.9 0.4 0.69 10.2 0.0 2.5 3 0 0 3 3 3 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin FA_desaturase PF00487.24 KKK14678.1 - 3.8e-19 69.5 12.1 5.5e-19 69.0 12.1 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.10 KKK14678.1 - 6.4e-18 64.0 0.2 6.4e-18 64.0 0.2 1.7 2 0 0 2 2 2 1 Sphingolipid Delta4-desaturase (DES) Peptidase_M24 PF00557.24 KKK14679.1 - 1.7e-36 125.9 0.1 2.4e-36 125.4 0.1 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 PGA2 PF07543.12 KKK14679.1 - 0.67 9.9 8.0 1.2 9.1 8.0 1.4 1 0 0 1 1 1 0 Protein trafficking PGA2 CCDC106 PF15794.5 KKK14679.1 - 2.5 7.8 5.6 3.8 7.2 5.6 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 GEN1_C PF18380.1 KKK14679.1 - 2.6 9.0 6.0 5.8 7.9 6.0 1.5 1 0 0 1 1 1 0 Holliday junction resolvase Gen1 C-terminal domain CDC45 PF02724.14 KKK14679.1 - 4.6 5.4 8.4 6 5.0 8.4 1.1 1 0 0 1 1 1 0 CDC45-like protein SAP25 PF15476.6 KKK14680.1 - 0.031 14.0 0.0 0.051 13.2 0.0 1.3 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP25 SPAR_C PF11881.8 KKK14680.1 - 0.051 13.5 0.1 0.079 12.9 0.1 1.2 1 0 0 1 1 1 0 C-terminal domain of SPAR protein Aa_trans PF01490.18 KKK14681.1 - 4.8e-72 242.9 31.4 5.9e-72 242.6 31.4 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Vfa1 PF08432.10 KKK14682.1 - 7.8e-60 202.3 18.0 8.8e-60 202.1 18.0 1.0 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 SAGA-Tad1 PF12767.7 KKK14682.1 - 0.0019 18.0 6.4 0.002 17.9 6.4 1.1 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit SprA-related PF12118.8 KKK14682.1 - 0.035 13.2 8.6 0.041 13.0 8.6 1.2 1 0 0 1 1 1 0 SprA-related family AAA_15 PF13175.6 KKK14682.1 - 0.09 12.5 13.1 0.1 12.3 13.1 1.0 1 0 0 1 1 1 0 AAA ATPase domain NPR3 PF03666.13 KKK14682.1 - 0.094 11.5 12.1 0.11 11.3 12.1 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 RR_TM4-6 PF06459.12 KKK14682.1 - 0.11 12.3 14.6 0.15 11.8 14.6 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SAPS PF04499.15 KKK14682.1 - 0.14 10.9 7.9 0.16 10.8 7.9 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF913 PF06025.12 KKK14682.1 - 0.22 10.5 4.5 0.27 10.2 4.5 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) HCMV_UL139 PF12507.8 KKK14682.1 - 0.37 11.2 10.1 0.82 10.1 9.9 1.7 1 1 0 1 1 1 0 Human Cytomegalovirus UL139 protein SLC12 PF03522.15 KKK14682.1 - 0.49 9.3 9.3 0.57 9.1 9.3 1.1 1 0 0 1 1 1 0 Solute carrier family 12 MMU163 PF17119.5 KKK14682.1 - 0.59 9.3 5.4 0.81 8.8 5.4 1.1 1 0 0 1 1 1 0 Mitochondrial protein up-regulated during meiosis DUF4407 PF14362.6 KKK14682.1 - 0.69 9.2 10.6 0.85 8.9 10.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CDC45 PF02724.14 KKK14682.1 - 0.69 8.1 16.8 0.76 8.0 16.8 1.0 1 0 0 1 1 1 0 CDC45-like protein XRN_M PF17846.1 KKK14682.1 - 1.5 7.7 10.0 1.8 7.5 10.0 1.1 1 0 0 1 1 1 0 Xrn1 helical domain Presenilin PF01080.17 KKK14682.1 - 1.8 7.3 11.8 2.1 7.0 11.8 1.1 1 0 0 1 1 1 0 Presenilin ATP11 PF06644.11 KKK14682.1 - 1.9 8.2 15.4 2.4 7.9 15.4 1.2 1 0 0 1 1 1 0 ATP11 protein Neur_chan_memb PF02932.16 KKK14682.1 - 3.1 7.8 5.5 3.4 7.6 5.5 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region NARP1 PF12569.8 KKK14682.1 - 4.5 6.1 18.4 5.6 5.8 18.4 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 TP53IP5 PF15331.6 KKK14682.1 - 5 7.2 11.9 6.7 6.8 11.9 1.2 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 DASH_Spc19 PF08287.11 KKK14682.1 - 5.4 6.9 22.7 10 6.0 22.7 1.5 1 1 0 1 1 1 0 Spc19 RRN3 PF05327.11 KKK14682.1 - 5.6 5.4 12.6 6.1 5.3 12.6 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 FAM60A PF15396.6 KKK14682.1 - 5.7 6.9 16.0 5.8 6.9 12.4 2.0 2 0 0 2 2 2 0 Protein Family FAM60A Pkinase PF00069.25 KKK14683.1 - 2.2e-25 89.5 0.0 2.8e-25 89.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK14683.1 - 9.6e-10 38.2 0.0 1.8e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase FMN_dh PF01070.18 KKK14684.1 - 1e-97 327.4 0.5 2.6e-63 214.2 0.1 2.1 1 1 1 2 2 2 2 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 KKK14684.1 - 1.4e-18 66.8 0.0 3.1e-18 65.7 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 KKK14684.1 - 4.2e-05 22.9 0.0 7.4e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase ThiG PF05690.14 KKK14684.1 - 0.0014 18.0 0.0 0.2 10.9 0.0 2.2 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG IMPDH PF00478.25 KKK14684.1 - 0.0087 15.1 0.0 0.017 14.1 0.0 1.5 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 KKK14684.1 - 0.078 12.4 0.1 0.23 10.8 0.0 1.7 1 1 1 2 2 2 0 Nitronate monooxygenase TatD_DNase PF01026.21 KKK14685.1 - 2.3e-51 174.7 0.0 2.7e-51 174.4 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase Y_phosphatase2 PF03162.13 KKK14686.1 - 9.2e-49 165.2 0.0 1.2e-48 164.8 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 KKK14686.1 - 1.1e-09 38.7 0.0 2e-09 37.8 0.0 1.4 1 1 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 KKK14686.1 - 0.00047 20.0 0.0 0.00065 19.5 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KKK14686.1 - 0.0059 16.2 0.0 0.0084 15.7 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 KKK14686.1 - 0.0063 16.6 0.0 0.01 16.0 0.0 1.3 1 0 0 1 1 1 1 Inositol hexakisphosphate CDKN3 PF05706.12 KKK14686.1 - 0.098 12.3 0.1 0.16 11.6 0.1 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) 4HBT PF03061.22 KKK14687.1 - 0.041 14.2 0.1 4.5 7.7 0.1 2.5 2 0 0 2 2 2 0 Thioesterase superfamily tRNA-synt_2 PF00152.20 KKK14689.1 - 6.6e-67 225.8 0.0 1.1e-66 225.0 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) DUF2156 PF09924.9 KKK14689.1 - 3.5e-16 59.1 0.0 5.4e-16 58.5 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2156) tRNA_anti-codon PF01336.25 KKK14689.1 - 0.0002 21.3 0.0 0.00048 20.1 0.0 1.7 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 KKK14689.1 - 0.0075 15.8 0.5 2.5 7.5 0.1 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) MCM_N PF14551.6 KKK14689.1 - 0.05 14.2 0.0 0.13 12.9 0.0 1.7 1 0 0 1 1 1 0 MCM N-terminal domain Acetyltransf_6 PF13480.7 KKK14689.1 - 0.064 13.4 1.2 0.19 11.9 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Dsh_C PF12316.8 KKK14689.1 - 0.49 10.8 5.7 0.96 9.8 5.7 1.4 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal Tubulin PF00091.25 KKK14691.1 - 3e-67 226.7 0.0 4.6e-67 226.1 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KKK14691.1 - 3.7e-50 169.3 0.1 8.9e-50 168.1 0.1 1.7 2 0 0 2 2 2 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 KKK14691.1 - 0.0023 17.6 0.0 0.0053 16.5 0.0 1.6 1 0 0 1 1 1 1 Tubulin domain EF-hand_4 PF12763.7 KKK14692.1 - 9.1e-37 125.2 0.0 2e-14 53.4 0.0 3.5 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 KKK14692.1 - 7.2e-09 34.6 0.0 0.002 17.6 0.0 5.1 6 0 0 6 6 6 2 EF hand EF-hand_7 PF13499.6 KKK14692.1 - 1.7e-08 34.8 0.0 0.00053 20.4 0.1 4.3 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 KKK14692.1 - 2e-07 30.4 0.1 0.48 10.5 0.0 5.7 6 0 0 6 6 6 1 EF-hand domain UBA PF00627.31 KKK14692.1 - 0.0003 20.6 0.0 0.00059 19.7 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain EF-hand_8 PF13833.6 KKK14692.1 - 0.0036 17.1 0.0 0.31 10.9 0.0 3.6 3 1 1 4 4 4 1 EF-hand domain pair FUSC PF04632.12 KKK14692.1 - 0.0074 14.9 4.4 0.011 14.3 4.4 1.1 1 0 0 1 1 1 1 Fusaric acid resistance protein family TMF_TATA_bd PF12325.8 KKK14692.1 - 0.14 12.4 14.8 0.18 12.0 5.6 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Tup_N PF08581.10 KKK14692.1 - 0.22 11.9 6.3 0.56 10.6 6.3 1.7 1 0 0 1 1 1 0 Tup N-terminal Nsp1_C PF05064.13 KKK14692.1 - 0.44 10.4 4.5 1.1 9.1 4.5 1.5 1 0 0 1 1 1 0 Nsp1-like C-terminal region GAS PF13851.6 KKK14692.1 - 0.66 9.3 20.6 1.1 8.5 3.9 2.2 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding TMPIT PF07851.13 KKK14692.1 - 3.5 6.8 8.4 4.8 6.3 8.4 1.2 1 0 0 1 1 1 0 TMPIT-like protein Sulfatase_C PF14707.6 KKK14692.1 - 3.6 8.3 6.1 24 5.7 1.1 2.7 2 1 0 2 2 2 0 C-terminal region of aryl-sulfatase Spc7 PF08317.11 KKK14692.1 - 3.8 6.3 22.9 0.6 8.9 8.9 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF4407 PF14362.6 KKK14692.1 - 6.9 5.9 14.6 15 4.8 14.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Glyco_transf_8 PF01501.20 KKK14703.1 - 2.5e-22 79.7 0.1 2e-21 76.7 0.1 2.1 1 1 0 1 1 1 1 Glycosyl transferase family 8 Adenylsucc_synt PF00709.21 KKK14703.1 - 0.17 10.8 0.1 0.24 10.3 0.1 1.1 1 0 0 1 1 1 0 Adenylosuccinate synthetase Abhydrolase_6 PF12697.7 KKK14704.1 - 4.8e-16 60.0 0.0 8.7e-15 55.9 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KKK14704.1 - 1.8e-15 57.3 0.0 1.7e-14 54.1 0.1 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KKK14704.1 - 6.5e-07 28.9 0.0 1.9e-06 27.4 0.0 1.8 3 0 0 3 3 3 1 Serine aminopeptidase, S33 EHN PF06441.12 KKK14704.1 - 0.023 15.0 0.2 0.055 13.8 0.2 1.6 1 0 0 1 1 1 0 Epoxide hydrolase N terminus LIDHydrolase PF10230.9 KKK14704.1 - 0.028 14.0 0.0 0.054 13.0 0.0 1.4 1 1 0 1 1 1 0 Lipid-droplet associated hydrolase Abhydrolase_2 PF02230.16 KKK14704.1 - 0.052 13.3 0.0 11 5.7 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase VHS PF00790.19 KKK14705.1 - 2e-31 108.7 0.6 8.1e-24 84.1 0.1 2.4 2 0 0 2 2 2 2 VHS domain SH3_1 PF00018.28 KKK14705.1 - 4.9e-16 58.1 0.0 1.1e-15 56.9 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KKK14705.1 - 6.3e-15 54.8 0.1 1.2e-14 53.9 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KKK14705.1 - 1.1e-13 50.6 0.0 2.1e-13 49.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain GAT PF03127.14 KKK14705.1 - 1.6e-10 41.1 1.6 3.9e-10 39.9 1.6 1.7 1 0 0 1 1 1 1 GAT domain UIM PF02809.20 KKK14705.1 - 0.066 13.2 3.5 0.19 11.7 3.5 1.8 1 0 0 1 1 1 0 Ubiquitin interaction motif Antimicrobial11 PF08106.11 KKK14705.1 - 0.44 10.7 7.5 1.1 9.4 0.1 3.0 2 0 0 2 2 2 0 Formaecin family UCH_1 PF13423.6 KKK14706.1 - 2.4e-93 313.2 0.2 3.3e-93 312.8 0.2 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.24 KKK14706.1 - 3.6e-16 60.1 0.0 1.4e-15 58.3 0.0 2.1 2 0 0 2 2 2 1 Exonuclease UCH PF00443.29 KKK14706.1 - 1.5e-05 24.6 0.0 0.0001 21.9 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase KH_1 PF00013.29 KKK14707.1 - 1.2e-93 306.9 22.3 1.3e-11 44.2 0.1 13.6 13 1 0 13 13 13 9 KH domain KH_2 PF07650.17 KKK14707.1 - 8.4e-11 41.6 26.8 0.0054 16.5 0.3 7.8 6 2 2 8 8 8 5 KH domain SLS PF14611.6 KKK14707.1 - 3.5e-10 40.1 4.1 0.082 12.7 0.1 8.1 4 3 3 9 9 9 2 Mitochondrial inner-membrane-bound regulator KH_4 PF13083.6 KKK14707.1 - 0.0054 16.6 7.1 26 4.8 0.0 5.9 6 0 0 6 6 6 0 KH domain RL10P_insert PF17777.1 KKK14707.1 - 0.016 15.2 0.1 0.066 13.2 0.1 2.1 1 0 0 1 1 1 0 Insertion domain in 60S ribosomal protein L10P KH_5 PF13184.6 KKK14707.1 - 0.26 11.4 6.6 49 4.1 0.2 5.8 6 0 0 6 6 6 0 NusA-like KH domain YbbR PF07949.12 KKK14707.1 - 4 7.8 7.3 8.9 6.7 0.1 4.9 6 0 0 6 6 6 0 YbbR-like protein Pkinase PF00069.25 KKK14708.1 - 7e-72 242.0 0.0 1.2e-71 241.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK14708.1 - 6.4e-45 153.5 0.0 1e-44 152.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 KKK14708.1 - 6.8e-22 77.6 0.1 1.8e-21 76.2 0.1 1.8 1 0 0 1 1 1 1 P21-Rho-binding domain Pkinase_fungal PF17667.1 KKK14708.1 - 7.3e-07 28.3 0.7 1.8e-06 27.0 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 KKK14708.1 - 1.6e-06 27.7 0.0 2.6e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KKK14708.1 - 0.055 12.8 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KKK14708.1 - 0.17 10.8 0.3 0.45 9.4 0.3 1.6 1 1 0 1 1 1 0 Haspin like kinase domain DSHCT PF08148.12 KKK14708.1 - 0.18 11.5 0.0 0.41 10.3 0.0 1.5 1 0 0 1 1 1 0 DSHCT (NUC185) domain FTA2 PF13095.6 KKK14708.1 - 0.32 10.6 2.9 0.38 10.3 0.1 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 KKK14708.1 - 2.7 7.9 10.3 0.41 10.5 0.2 3.0 2 1 1 3 3 3 0 Phosphotransferase enzyme family AMP-binding PF00501.28 KKK14709.1 - 2.4e-89 299.9 0.1 3.1e-89 299.5 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KKK14709.1 - 2.2e-26 92.6 1.3 3.8e-25 88.7 0.6 2.6 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 KKK14709.1 - 9e-15 54.3 0.1 2.3e-14 53.0 0.1 1.8 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus FGGY_C PF02782.16 KKK14711.1 - 1.3e-74 250.2 0.9 2.5e-74 249.3 0.9 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 KKK14711.1 - 4.6e-60 203.2 0.0 6.1e-60 202.8 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.20 KKK14711.1 - 0.0012 18.4 0.6 0.033 13.7 0.0 2.2 2 0 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family Peptidase_M41 PF01434.18 KKK14712.1 - 1.7e-56 191.1 0.5 3.2e-56 190.2 0.2 1.6 2 0 0 2 2 2 1 Peptidase family M41 AAA PF00004.29 KKK14712.1 - 1.6e-42 145.1 0.0 5.1e-42 143.4 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KKK14712.1 - 4.1e-11 42.5 0.0 1e-10 41.3 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 KKK14712.1 - 1.2e-05 25.3 0.0 4.6e-05 23.4 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 KKK14712.1 - 6.9e-05 22.2 1.6 0.00015 21.1 0.0 2.2 3 0 0 3 3 3 1 TIP49 P-loop domain AAA_22 PF13401.6 KKK14712.1 - 7.6e-05 23.0 0.4 0.025 14.9 0.3 3.2 2 2 0 2 2 2 1 AAA domain RuvB_N PF05496.12 KKK14712.1 - 0.00023 20.9 0.0 0.00068 19.4 0.0 1.8 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KKK14712.1 - 0.00042 20.7 6.2 0.00043 20.7 1.1 3.3 2 2 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.6 KKK14712.1 - 0.0032 17.6 0.2 0.013 15.6 0.0 2.2 3 0 0 3 3 1 1 AAA domain IstB_IS21 PF01695.17 KKK14712.1 - 0.012 15.4 0.0 0.022 14.5 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_2 PF07724.14 KKK14712.1 - 0.016 15.3 0.0 0.051 13.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_25 PF13481.6 KKK14712.1 - 0.022 14.3 1.5 0.79 9.3 0.3 2.5 1 1 1 2 2 2 0 AAA domain Mg_chelatase PF01078.21 KKK14712.1 - 0.025 13.9 0.2 0.051 13.0 0.2 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 KKK14712.1 - 0.027 15.0 0.0 0.09 13.3 0.0 2.0 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KKK14712.1 - 0.054 13.4 0.4 1.9 8.4 0.1 2.6 2 0 0 2 2 2 0 NACHT domain ATPase PF06745.13 KKK14712.1 - 0.064 12.6 0.4 1.5 8.1 0.0 2.6 3 0 0 3 3 3 0 KaiC DUF815 PF05673.13 KKK14712.1 - 0.072 12.2 0.0 0.16 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_17 PF13207.6 KKK14712.1 - 0.076 13.4 0.0 0.2 12.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KKK14712.1 - 0.08 13.2 0.2 0.2 11.9 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_7 PF12775.7 KKK14712.1 - 0.12 11.8 0.1 0.4 10.2 0.1 1.8 1 1 0 1 1 1 0 P-loop containing dynein motor region Zeta_toxin PF06414.12 KKK14712.1 - 0.23 10.7 2.4 0.83 8.9 0.5 2.5 2 1 1 3 3 3 0 Zeta toxin NTP_transferase PF00483.23 KKK14714.1 - 3.1e-52 177.6 0.0 6e-52 176.7 0.0 1.4 2 0 0 2 2 2 1 Nucleotidyl transferase Hexapep PF00132.24 KKK14714.1 - 2.5e-14 52.3 9.1 7.9e-11 41.2 3.1 3.9 1 1 1 2 2 2 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 KKK14714.1 - 2.9e-10 40.7 0.0 4.2e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.6 KKK14714.1 - 1.8e-06 27.6 1.5 1.8e-06 27.6 1.5 3.0 3 0 0 3 3 3 1 Hexapeptide repeat of succinyl-transferase DUF4954 PF16314.5 KKK14714.1 - 0.0096 14.1 0.1 0.014 13.6 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) IspD PF01128.19 KKK14714.1 - 0.17 11.6 0.0 0.28 10.9 0.0 1.3 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Fungal_trans PF04082.18 KKK14715.1 - 1.2e-20 73.6 0.5 1.7e-20 73.1 0.5 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK14715.1 - 0.075 13.2 4.9 0.16 12.1 4.9 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Cutinase PF01083.22 KKK14716.1 - 8.2e-48 162.7 1.6 9.5e-48 162.5 1.6 1.0 1 0 0 1 1 1 1 Cutinase VirJ PF06057.11 KKK14716.1 - 0.0003 20.7 0.0 0.00036 20.5 0.0 1.1 1 0 0 1 1 1 1 Bacterial virulence protein (VirJ) PE-PPE PF08237.11 KKK14716.1 - 0.0012 18.4 0.1 0.0017 18.0 0.1 1.2 1 0 0 1 1 1 1 PE-PPE domain LVIVD PF08309.11 KKK14717.1 - 7.4e-10 38.0 1.6 0.32 10.4 0.0 5.3 5 0 0 5 5 5 5 LVIVD repeat Brr6_like_C_C PF10104.9 KKK14718.1 - 3.2e-44 149.9 0.2 4.2e-44 149.6 0.2 1.1 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain DUF2202 PF09968.9 KKK14719.1 - 0.014 15.2 0.3 0.023 14.6 0.3 1.3 1 0 0 1 1 1 0 Uncharacterized protein domain (DUF2202) DUF1811 PF08838.10 KKK14719.1 - 0.023 14.9 0.2 0.039 14.2 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1811) Par3_HAL_N_term PF12053.8 KKK14719.1 - 0.21 11.8 0.1 0.21 11.8 0.1 1.7 1 1 1 2 2 2 0 N-terminal of Par3 and HAL proteins Bud13 PF09736.9 KKK14720.1 - 1.6e-35 122.6 11.1 2.1e-35 122.2 0.9 3.2 2 2 1 3 3 3 2 Pre-mRNA-splicing factor of RES complex LUD_dom PF02589.15 KKK14720.1 - 2.7 7.7 4.7 0.75 9.5 1.1 1.7 2 0 0 2 2 2 0 LUD domain DNA_binding_1 PF01035.20 KKK14721.1 - 2e-24 85.5 0.0 2.5e-24 85.2 0.0 1.1 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain DUF4224 PF13986.6 KKK14721.1 - 0.039 13.9 0.0 0.54 10.2 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4224) HsbA PF12296.8 KKK14722.1 - 4.3e-18 65.9 7.3 4.3e-18 65.9 7.3 2.4 2 1 0 2 2 2 1 Hydrophobic surface binding protein A Utp12 PF04003.12 KKK14723.1 - 1.9e-21 76.4 0.0 3.9e-21 75.4 0.0 1.6 1 0 0 1 1 1 1 Dip2/Utp12 Family Frataxin_Cyay PF01491.16 KKK14724.1 - 1e-36 125.3 0.0 1.4e-36 124.8 0.0 1.2 1 0 0 1 1 1 1 Frataxin-like domain GKAP PF03359.13 KKK14724.1 - 0.0027 17.3 0.0 0.0043 16.7 0.0 1.3 1 0 0 1 1 1 1 Guanylate-kinase-associated protein (GKAP) protein HAUS4 PF14735.6 KKK14725.1 - 0.006 16.3 1.9 0.021 14.6 1.9 1.9 1 1 0 1 1 1 1 HAUS augmin-like complex subunit 4 Ku_C PF03730.14 KKK14725.1 - 0.049 14.3 1.4 2.4 8.9 0.4 3.7 3 1 1 4 4 4 0 Ku70/Ku80 C-terminal arm DinB_2 PF12867.7 KKK14725.1 - 1.2 9.7 9.1 5.9 7.4 0.7 2.8 2 1 1 3 3 3 0 DinB superfamily Bromodomain PF00439.25 KKK14726.1 - 4.3e-36 122.8 3.0 5.4e-18 64.8 0.2 2.7 3 0 0 3 3 3 2 Bromodomain BET PF17035.5 KKK14726.1 - 6.1e-21 74.4 2.1 1.7e-19 69.7 0.9 2.6 2 0 0 2 2 2 1 Bromodomain extra-terminal - transcription regulation CDC45 PF02724.14 KKK14726.1 - 0.19 9.9 12.8 0.32 9.2 12.8 1.3 1 0 0 1 1 1 0 CDC45-like protein DUF3573 PF12097.8 KKK14726.1 - 2.1 7.1 3.2 3.4 6.4 3.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Allexi_40kDa PF05549.11 KKK14726.1 - 3.5 7.1 5.2 8.6 5.8 5.2 1.6 1 0 0 1 1 1 0 Allexivirus 40kDa protein AKAP7_NLS PF10469.9 KKK14727.1 - 2.5e-13 50.4 0.0 1.1e-12 48.3 0.0 2.0 1 1 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain zf-CSL PF05207.13 KKK14728.1 - 5.2e-23 80.5 0.2 6.2e-23 80.3 0.2 1.1 1 0 0 1 1 1 1 CSL zinc finger Prok-RING_1 PF14446.6 KKK14728.1 - 0.28 11.1 3.0 0.56 10.2 3.0 1.5 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 Pyridoxal_deC PF00282.19 KKK14729.1 - 1.7e-12 46.8 0.0 5e-07 28.8 0.0 2.2 2 0 0 2 2 2 2 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 KKK14729.1 - 0.0049 15.9 0.0 0.022 13.7 0.0 1.8 2 0 0 2 2 2 1 Aminotransferase class-V HMGL-like PF00682.19 KKK14730.1 - 2.2e-79 266.8 0.2 3e-79 266.3 0.2 1.2 1 0 0 1 1 1 1 HMGL-like TMCO5 PF14992.6 KKK14730.1 - 0.0032 17.1 0.0 0.0045 16.6 0.0 1.2 1 0 0 1 1 1 1 TMCO5 family DUF4448 PF14610.6 KKK14731.1 - 5.7e-39 133.9 0.0 8.7e-39 133.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) stn_TNFRSF12A PF12191.8 KKK14731.1 - 0.063 13.5 0.0 0.1 12.8 0.0 1.3 1 0 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain LapA_dom PF06305.11 KKK14731.1 - 0.12 12.2 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain PTH2 PF01981.16 KKK14733.1 - 3.6e-42 143.3 0.6 5.5e-42 142.7 0.6 1.3 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 tRNA_synt_1c_R2 PF04557.15 KKK14733.1 - 0.038 14.9 1.3 0.52 11.3 0.8 2.2 2 0 0 2 2 2 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 GOLD_2 PF13897.6 KKK14733.1 - 0.079 13.5 0.2 0.11 13.0 0.2 1.3 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking AIPR PF10592.9 KKK14733.1 - 0.11 12.1 0.1 0.14 11.7 0.1 1.1 1 0 0 1 1 1 0 AIPR protein HA1 PF18239.1 KKK14733.1 - 0.15 11.9 0.0 0.33 10.8 0.0 1.5 1 0 0 1 1 1 0 Hemagglutinin I SART-1 PF03343.13 KKK14734.1 - 7.4e-173 576.5 57.7 2e-172 575.1 57.7 1.6 1 1 0 1 1 1 1 SART-1 family DUF2330 PF10092.9 KKK14735.1 - 0.019 14.1 0.0 0.032 13.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2330) Aminotran_1_2 PF00155.21 KKK14736.1 - 2.3e-91 306.7 0.0 2.6e-91 306.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Sec6 PF06046.13 KKK14737.1 - 1.5e-153 512.3 3.6 3.2e-152 507.8 3.6 2.2 1 1 0 1 1 1 1 Exocyst complex component Sec6 Vps53_N PF04100.12 KKK14737.1 - 0.0012 17.8 12.9 0.0026 16.8 3.5 2.3 2 0 0 2 2 2 2 Vps53-like, N-terminal HEAT_2 PF13646.6 KKK14737.1 - 0.036 14.5 0.7 0.32 11.4 0.1 2.9 3 0 0 3 3 3 0 HEAT repeats DUF4972 PF16342.5 KKK14737.1 - 0.054 13.2 1.1 0.57 9.9 0.2 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4972) Dynactin_p22 PF07426.11 KKK14737.1 - 0.2 11.5 4.8 1.5 8.7 3.9 2.7 2 1 0 2 2 2 0 Dynactin subunit p22 BORCS8 PF10167.9 KKK14737.1 - 0.35 10.8 1.5 1.4 8.9 0.3 2.3 2 0 0 2 2 2 0 BLOC-1-related complex sub-unit 8 NPV_P10 PF05531.12 KKK14737.1 - 0.51 10.8 3.5 12 6.5 1.2 3.0 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Spc7 PF08317.11 KKK14737.1 - 0.91 8.3 7.7 2.1 7.1 7.7 1.6 1 0 0 1 1 1 0 Spc7 kinetochore protein Ribosomal_L30 PF00327.20 KKK14738.1 - 1.9e-16 59.6 0.3 2.7e-16 59.2 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e DUF3445 PF11927.8 KKK14739.1 - 4.6e-13 49.3 0.1 6.9e-13 48.8 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) DEAD_2 PF06733.15 KKK14740.1 - 1.8e-57 193.8 0.2 4.2e-57 192.6 0.2 1.7 1 0 0 1 1 1 1 DEAD_2 HBB PF06777.11 KKK14740.1 - 1.1e-49 168.7 3.6 4.5e-45 153.7 0.6 2.7 3 0 0 3 3 3 2 Helical and beta-bridge domain Helicase_C_2 PF13307.6 KKK14740.1 - 3.1e-44 151.2 0.0 8.9e-44 149.7 0.0 1.8 1 0 0 1 1 1 1 Helicase C-terminal domain ResIII PF04851.15 KKK14740.1 - 6.7e-05 22.9 0.1 0.0058 16.7 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KKK14740.1 - 0.0019 18.0 0.0 0.2 11.4 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF2075 PF09848.9 KKK14740.1 - 0.018 14.3 0.0 1.6 7.9 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) SNF2_N PF00176.23 KKK14740.1 - 0.043 12.5 0.0 0.33 9.6 0.0 2.1 1 1 0 1 1 1 0 SNF2 family N-terminal domain AAA_22 PF13401.6 KKK14740.1 - 0.058 13.7 2.6 4.7 7.5 0.0 3.5 4 0 0 4 4 4 0 AAA domain DUF2492 PF10678.9 KKK14740.1 - 0.097 13.0 0.2 0.37 11.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2492) LCM PF04072.14 KKK14741.1 - 2.3e-21 76.6 0.0 7.5e-21 74.9 0.0 1.9 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase C1_1 PF00130.22 KKK14741.1 - 0.13 12.2 1.0 0.28 11.1 1.0 1.5 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) SUN PF03856.13 KKK14742.1 - 2.3e-80 269.6 11.2 2.3e-80 269.6 11.2 1.6 2 0 0 2 2 2 1 Beta-glucosidase (SUN family) zinc-ribbons_6 PF07191.12 KKK14742.1 - 0.057 13.4 0.9 0.1 12.6 0.2 1.8 2 0 0 2 2 2 0 zinc-ribbons TT_ORF1 PF02956.14 KKK14742.1 - 0.95 8.1 10.5 1.4 7.5 10.5 1.2 1 0 0 1 1 1 0 TT viral orf 1 Apt1 PF10351.9 KKK14742.1 - 1.7 7.4 17.0 2.6 6.8 17.0 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Dicty_REP PF05086.12 KKK14742.1 - 2.9 5.8 20.7 4.2 5.2 20.7 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Ist1 PF03398.14 KKK14743.1 - 9.1e-44 149.3 0.2 1.4e-21 77.1 1.1 2.1 2 0 0 2 2 2 2 Regulator of Vps4 activity in the MVB pathway SAPS PF04499.15 KKK14743.1 - 0.0027 16.6 0.0 0.0033 16.3 0.0 1.1 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein Glyco_transf_22 PF03901.17 KKK14744.1 - 6.9e-62 210.0 17.0 9.3e-55 186.5 14.7 2.9 2 1 0 2 2 2 2 Alg9-like mannosyltransferase family Gar1 PF04410.14 KKK14745.1 - 1.6e-46 157.9 0.1 5.1e-46 156.2 0.1 1.9 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region PRP3 PF08572.10 KKK14746.1 - 1.7e-74 250.3 5.0 3.4e-74 249.3 5.0 1.5 1 0 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.12 KKK14746.1 - 2.3e-47 160.8 0.2 2.3e-47 160.8 0.2 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1115) RNA_pol_Rpb1_5 PF04998.17 KKK14747.1 - 1.5e-84 283.6 0.2 2.9e-84 282.6 0.2 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 KKK14747.1 - 5.1e-67 225.2 0.0 1.1e-66 224.1 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 KKK14747.1 - 9.8e-34 116.6 0.0 1.5e-32 112.7 0.0 2.9 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.12 KKK14747.1 - 6.3e-23 81.6 2.5 1.5e-21 77.0 1.3 2.9 2 1 0 2 2 2 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.17 KKK14747.1 - 7.6e-16 58.0 0.0 3.7e-15 55.8 0.0 2.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 FA_desaturase PF00487.24 KKK14748.1 - 1.1e-14 54.9 26.9 1.1e-14 54.9 26.9 1.5 1 1 1 2 2 2 1 Fatty acid desaturase MFS_1 PF07690.16 KKK14749.1 - 1.2e-14 54.0 21.3 1.2e-14 54.0 21.3 2.3 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_3 PF05977.13 KKK14749.1 - 0.031 12.7 0.4 0.051 12.0 0.4 1.2 1 0 0 1 1 1 0 Transmembrane secretion effector SAICAR_synt PF01259.18 KKK14750.1 - 6e-53 180.0 0.0 6.7e-53 179.9 0.0 1.0 1 0 0 1 1 1 1 SAICAR synthetase FAD_binding_3 PF01494.19 KKK14751.1 - 2.4e-84 283.6 0.1 2.9e-84 283.3 0.1 1.1 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KKK14751.1 - 3.2e-05 24.1 0.1 0.00029 21.0 0.1 2.6 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KKK14751.1 - 3.3e-05 23.7 4.7 0.00027 20.6 1.0 2.3 1 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KKK14751.1 - 0.00012 21.3 0.1 0.00021 20.5 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KKK14751.1 - 0.00063 18.6 0.2 0.0012 17.6 0.2 1.4 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.17 KKK14751.1 - 0.00094 18.5 0.1 0.0016 17.7 0.1 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 KKK14751.1 - 0.001 18.4 0.2 0.0027 17.0 0.2 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KKK14751.1 - 0.0011 18.3 0.2 0.0021 17.4 0.2 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KKK14751.1 - 0.0019 17.3 0.1 0.0046 16.1 0.1 1.6 1 0 0 1 1 1 1 Lycopene cyclase protein Trp_halogenase PF04820.14 KKK14751.1 - 0.003 16.5 0.0 0.0054 15.6 0.0 1.4 1 0 0 1 1 1 1 Tryptophan halogenase SE PF08491.10 KKK14751.1 - 0.018 14.1 0.0 0.052 12.6 0.0 1.8 1 1 0 1 1 1 0 Squalene epoxidase Clp_N PF02861.20 KKK14751.1 - 0.11 12.6 0.1 0.29 11.3 0.1 1.6 1 0 0 1 1 1 0 Clp amino terminal domain, pathogenicity island component NAD_binding_9 PF13454.6 KKK14751.1 - 0.14 12.2 1.2 0.4 10.7 0.1 2.3 3 0 0 3 3 3 0 FAD-NAD(P)-binding Pyr_redox PF00070.27 KKK14751.1 - 0.21 12.2 1.6 1.1 9.9 0.1 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Glycogen_syn PF05693.13 KKK14752.1 - 0 1151.9 0.0 0 1151.7 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glyco_trans_4_4 PF13579.6 KKK14752.1 - 1e-05 26.0 0.1 2.1e-05 25.0 0.1 1.6 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.6 KKK14752.1 - 1.2e-05 25.4 0.6 2.5e-05 24.3 0.6 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 KKK14752.1 - 0.00021 21.7 0.0 0.023 15.2 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 KKK14752.1 - 0.00024 20.7 0.0 0.0031 17.0 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferases group 1 ANAPC8 PF04049.13 KKK14753.1 - 1.1e-52 177.8 1.1 2e-52 177.0 0.0 2.0 2 0 0 2 2 1 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_1 PF00515.28 KKK14753.1 - 5.6e-24 82.9 3.1 0.00018 21.2 0.0 7.8 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_8 PF13181.6 KKK14753.1 - 6e-21 72.9 15.9 1.8e-05 24.6 0.0 9.8 10 0 0 10 10 9 4 Tetratricopeptide repeat TPR_2 PF07719.17 KKK14753.1 - 9.5e-18 62.8 18.1 0.06 13.5 2.8 9.5 10 0 0 10 10 9 5 Tetratricopeptide repeat TPR_11 PF13414.6 KKK14753.1 - 1.1e-11 44.2 1.3 1.1e-06 28.2 0.3 4.7 2 2 2 4 4 4 2 TPR repeat TPR_9 PF13371.6 KKK14753.1 - 4.4e-10 39.6 2.6 0.0013 18.9 0.1 5.4 5 2 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 KKK14753.1 - 1.2e-09 38.1 18.8 0.007 17.1 0.0 9.2 8 2 2 10 10 10 2 Tetratricopeptide repeat TPR_19 PF14559.6 KKK14753.1 - 1.7e-09 38.0 11.4 0.13 12.8 0.0 7.5 7 1 0 7 7 6 3 Tetratricopeptide repeat ANAPC3 PF12895.7 KKK14753.1 - 3.7e-08 33.5 16.7 0.13 12.5 0.2 6.2 6 1 0 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 KKK14753.1 - 5.1e-08 32.8 1.4 6.1 7.5 0.0 7.2 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_16 PF13432.6 KKK14753.1 - 6.9e-08 33.0 12.6 1.7e-05 25.4 0.0 6.3 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_12 PF13424.6 KKK14753.1 - 5.5e-06 26.6 11.4 1.9 8.9 0.0 6.6 6 2 1 7 7 6 1 Tetratricopeptide repeat TPR_15 PF13429.6 KKK14753.1 - 0.00029 20.1 8.4 0.00084 18.6 2.3 4.1 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 KKK14753.1 - 0.0035 17.3 10.8 2.9 8.1 0.0 6.5 7 0 0 7 7 6 1 Tetratricopeptide repeat RPN7 PF10602.9 KKK14753.1 - 0.071 12.8 1.2 1.3 8.7 0.1 2.9 3 0 0 3 3 3 0 26S proteasome subunit RPN7 TPR_6 PF13174.6 KKK14753.1 - 0.15 12.8 26.9 36 5.3 0.1 9.4 11 0 0 11 11 9 0 Tetratricopeptide repeat PPR PF01535.20 KKK14753.1 - 0.24 11.7 0.5 27 5.3 0.0 3.9 4 0 0 4 4 4 0 PPR repeat Sel1 PF08238.12 KKK14753.1 - 4.1 8.2 6.6 49 4.8 0.9 3.9 4 0 0 4 4 3 0 Sel1 repeat polyprenyl_synt PF00348.17 KKK14754.1 - 4.8e-89 297.8 0.0 5.7e-89 297.5 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase RNase_H2-Ydr279 PF09468.10 KKK14754.1 - 0.00039 20.7 0.0 0.0011 19.2 0.0 1.7 2 0 0 2 2 2 1 Ydr279p protein family (RNase H2 complex component) wHTH domain Arylsulfotran_2 PF14269.6 KKK14755.1 - 3.9e-62 210.3 5.7 5.8e-62 209.8 5.7 1.3 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 KKK14755.1 - 4e-17 62.2 4.2 1.2e-16 60.6 4.2 1.7 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) NMT1 PF09084.11 KKK14756.1 - 1.6e-79 266.8 0.0 2.1e-79 266.5 0.0 1.1 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.6 KKK14756.1 - 1.4e-05 25.0 0.2 0.087 12.5 0.0 3.2 3 1 0 3 3 3 2 NMT1-like family Fungal_trans PF04082.18 KKK14757.1 - 8.3e-31 107.0 2.0 1.3e-30 106.4 2.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK14757.1 - 0.0018 18.4 18.5 0.0037 17.4 18.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain OAD_gamma PF04277.13 KKK14758.1 - 0.46 11.1 2.7 0.46 11.1 2.7 1.1 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain SKG6 PF08693.10 KKK14758.1 - 0.96 8.9 4.8 1 8.9 4.8 1.1 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Asp PF00026.23 KKK14764.1 - 7.4e-75 252.3 4.8 9e-75 252.0 4.8 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KKK14764.1 - 8e-15 55.5 6.1 1.2e-12 48.4 6.1 3.2 2 2 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KKK14764.1 - 2e-07 31.6 0.5 0.024 15.3 0.2 3.7 2 1 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 KKK14764.1 - 0.00037 21.0 0.0 0.33 11.5 0.0 3.6 2 2 0 2 2 2 1 gag-polyprotein putative aspartyl protease TAXi_C PF14541.6 KKK14764.1 - 0.0066 16.2 0.0 0.014 15.2 0.0 1.6 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal Lipocalin_4 PF13648.6 KKK14764.1 - 3.5 8.6 7.7 2.2 9.3 1.8 2.9 3 0 0 3 3 3 0 Lipocalin-like domain tRNA-synt_1b PF00579.25 KKK14765.1 - 2.2e-69 234.0 0.0 2.9e-69 233.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) ATP-synt_C PF00137.21 KKK14775.1 - 1.2e-24 86.4 27.9 3.5e-14 52.9 11.3 2.4 2 0 0 2 2 2 2 ATP synthase subunit C SLATT_5 PF18160.1 KKK14775.1 - 0.56 9.5 1.9 0.62 9.3 0.1 1.8 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 Ras PF00071.22 KKK14776.1 - 3.1e-59 199.2 0.2 4e-59 198.8 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KKK14776.1 - 3.9e-37 127.1 0.3 7.9e-37 126.1 0.1 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKK14776.1 - 1.6e-17 63.5 0.1 1.9e-17 63.3 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KKK14776.1 - 3.1e-06 26.8 0.0 4.5e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 KKK14776.1 - 4.5e-06 26.3 0.1 2.9e-05 23.7 0.1 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KKK14776.1 - 6.5e-06 26.1 0.2 0.0057 16.6 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 KKK14776.1 - 1.5e-05 25.1 0.0 2.5e-05 24.3 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KKK14776.1 - 3.9e-05 23.1 0.2 4.8e-05 22.8 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region TIR_2 PF13676.6 KKK14776.1 - 0.079 13.6 0.0 0.13 12.8 0.0 1.4 1 0 0 1 1 1 0 TIR domain AAA_7 PF12775.7 KKK14776.1 - 0.091 12.3 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Dynamin_N PF00350.23 KKK14776.1 - 0.11 12.6 0.1 9 6.3 0.0 2.6 2 1 1 3 3 3 0 Dynamin family NIR_SIR PF01077.22 KKK14778.1 - 2e-48 163.9 0.0 1.6e-44 151.2 0.0 2.5 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.17 KKK14778.1 - 5.1e-30 103.1 0.0 4.2e-14 52.2 0.0 2.7 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.25 KKK14778.1 - 3.6e-26 92.1 0.0 8.5e-26 90.9 0.0 1.7 1 0 0 1 1 1 1 Flavodoxin POR_N PF01855.19 KKK14778.1 - 6e-08 32.7 2.0 1.1e-07 31.8 0.4 2.1 2 0 0 2 2 2 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg GARS_C PF02843.16 KKK14778.1 - 0.12 12.7 0.7 2.5 8.4 0.1 3.1 4 0 0 4 4 4 0 Phosphoribosylglycinamide synthetase, C domain Kei1 PF08552.11 KKK14779.1 - 3.1e-67 226.2 1.2 3.8e-67 225.9 1.2 1.1 1 0 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 DUF4875 PF16175.5 KKK14779.1 - 0.18 11.9 0.0 0.32 11.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4875) RNA_pol PF00940.19 KKK14780.1 - 4e-163 543.1 0.0 6.7e-131 436.9 0.0 2.2 1 1 1 2 2 2 2 DNA-dependent RNA polymerase RPOL_N PF14700.6 KKK14780.1 - 1.7e-91 307.1 0.3 2.8e-91 306.4 0.3 1.3 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal Sin_N PF04801.13 KKK14781.1 - 3.2e-22 79.4 0.0 6.6e-22 78.3 0.0 1.4 1 1 0 1 1 1 1 Sin-like protein conserved region Aldedh PF00171.22 KKK14784.1 - 1.3e-135 452.5 0.3 1.6e-135 452.2 0.3 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 KKK14784.1 - 0.062 12.3 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) Yos1 PF08571.10 KKK14786.1 - 6e-15 55.3 0.5 5.5e-08 33.0 0.0 2.1 2 0 0 2 2 2 2 Yos1-like UCH PF00443.29 KKK14787.1 - 1.2e-57 195.3 0.1 2.5e-57 194.3 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KKK14787.1 - 1.6e-26 93.7 0.6 1.8e-19 70.5 0.0 2.4 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 KKK14787.1 - 0.0046 16.5 4.8 0.04 13.4 2.1 2.7 3 0 0 3 3 3 1 Ubiquitin-specific peptidase-like, SUMO isopeptidase Dynamitin PF04912.14 KKK14788.1 - 1.4e-48 166.2 14.9 4.1e-41 141.6 8.6 2.1 2 0 0 2 2 2 2 Dynamitin CLZ PF16526.5 KKK14788.1 - 0.0019 18.5 15.2 2.3 8.7 0.0 4.7 4 1 1 5 5 5 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels AKNA PF12443.8 KKK14788.1 - 0.0079 16.8 0.6 0.0079 16.8 0.6 2.5 3 0 0 3 3 3 1 AT-hook-containing transcription factor Angiomotin_C PF12240.8 KKK14788.1 - 0.008 15.7 4.7 0.008 15.7 4.7 3.0 2 1 1 3 3 3 1 Angiomotin C terminal LPP PF04728.13 KKK14788.1 - 0.04 14.3 8.7 0.34 11.3 0.3 3.9 3 1 0 3 3 3 0 Lipoprotein leucine-zipper CorA PF01544.18 KKK14788.1 - 0.12 11.7 6.5 0.041 13.2 3.7 1.5 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein DUF4407 PF14362.6 KKK14788.1 - 0.13 11.6 19.1 0.21 10.9 10.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Prefoldin PF02996.17 KKK14788.1 - 2.2 8.2 9.6 5.3 7.0 0.0 3.5 3 1 0 4 4 4 0 Prefoldin subunit GrpE PF01025.19 KKK14788.1 - 2.9 7.5 7.0 0.8 9.4 2.5 2.2 2 0 0 2 2 2 0 GrpE Ax_dynein_light PF10211.9 KKK14788.1 - 3 7.8 8.0 0.21 11.5 2.2 2.0 2 1 0 2 2 2 0 Axonemal dynein light chain Plasmodium_Vir PF05795.11 KKK14788.1 - 3.1 7.1 4.7 5.4 6.3 4.7 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF572 PF04502.13 KKK14788.1 - 3.5 7.2 15.1 11 5.5 8.8 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF572) 5_nucleotid PF05761.14 KKK14788.1 - 4.1 6.2 6.9 0.15 10.9 1.2 1.4 2 0 0 2 2 2 0 5' nucleotidase family Glyco_transf_22 PF03901.17 KKK14789.1 - 2.7e-37 129.0 14.3 3.3e-37 128.7 14.3 1.2 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family DUF3267 PF11667.8 KKK14789.1 - 0.89 9.9 9.9 0.4 11.0 3.5 3.3 2 1 1 3 3 3 0 Putative zincin peptidase QRPTase_C PF01729.19 KKK14790.1 - 7.8e-47 159.2 0.7 8.7e-45 152.5 0.7 2.1 1 1 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.16 KKK14790.1 - 9.7e-20 70.4 0.0 3.6e-19 68.6 0.0 2.0 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, N-terminal domain Aldose_epim PF01263.20 KKK14791.1 - 2.7e-58 197.7 0.0 3e-58 197.5 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase Sec7 PF01369.20 KKK14792.1 - 3.3e-28 98.6 0.0 7.1e-28 97.5 0.0 1.4 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.6 KKK14792.1 - 2e-19 70.1 0.0 1.3e-18 67.5 0.0 2.1 2 0 0 2 2 2 1 Pleckstrin homology domain Cnn_1N PF07989.11 KKK14793.1 - 1.3e-23 82.9 11.0 1.3e-23 82.9 11.0 11.9 7 2 3 11 11 11 2 Centrosomin N-terminal motif 1 Mto2_bdg PF12808.7 KKK14793.1 - 1.9e-22 79.3 28.8 6.9e-19 67.9 11.9 11.0 11 2 2 13 13 13 2 Micro-tubular organiser Mto1 C-term Mto2-binding region MliC PF09864.9 KKK14793.1 - 0.15 12.0 0.0 0.6 10.1 0.0 2.0 2 0 0 2 2 2 0 Membrane-bound lysozyme-inhibitor of c-type lysozyme Zn_clus PF00172.18 KKK14794.1 - 1.4e-08 34.7 12.8 2.8e-08 33.7 12.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ras PF00071.22 KKK14795.1 - 2.8e-37 127.8 0.0 3.6e-36 124.2 0.0 2.0 1 1 0 1 1 1 1 Ras family Roc PF08477.13 KKK14795.1 - 2.9e-10 40.4 0.0 7.4e-10 39.1 0.0 1.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 KKK14795.1 - 0.0072 16.4 0.0 0.014 15.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 KKK14795.1 - 0.027 13.9 0.0 0.068 12.6 0.0 1.7 1 1 1 2 2 2 0 ADP-ribosylation factor family NB-ARC PF00931.22 KKK14795.1 - 0.061 12.5 0.0 0.19 10.9 0.0 1.8 2 0 0 2 2 2 0 NB-ARC domain UNC-50 PF05216.13 KKK14796.1 - 1.4e-83 279.8 6.6 1.7e-83 279.6 6.6 1.0 1 0 0 1 1 1 1 UNC-50 family RibD_C PF01872.17 KKK14797.1 - 3.6e-34 118.3 0.0 4.3e-34 118.1 0.0 1.1 1 0 0 1 1 1 1 RibD C-terminal domain WXG100 PF06013.12 KKK14798.1 - 0.0049 17.1 4.2 0.019 15.2 4.2 2.0 1 0 0 1 1 1 1 Proteins of 100 residues with WXG FlaC_arch PF05377.11 KKK14798.1 - 0.34 11.3 9.7 0.81 10.1 1.5 4.0 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) MCC-bdg_PDZ PF10506.9 KKK14798.1 - 1.7 8.7 5.9 5.7 7.0 5.9 1.9 1 0 0 1 1 1 0 PDZ domain of MCC-2 bdg protein for Usher syndrome DUF3431 PF11913.8 KKK14800.1 - 8.6e-79 264.3 0.1 1.1e-78 264.0 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) Phage_holin_5_1 PF06946.11 KKK14801.1 - 1.3 9.5 10.1 0.16 12.4 0.4 2.8 3 0 0 3 3 3 0 Bacteriophage A118-like holin, Hol118 Bestrophin PF01062.21 KKK14802.1 - 1.4e-38 132.9 0.0 2.5e-38 132.2 0.0 1.2 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel T6SS_VasE PF05936.12 KKK14802.1 - 0.059 12.1 0.0 0.084 11.6 0.0 1.1 1 0 0 1 1 1 0 Bacterial Type VI secretion, VC_A0110, EvfL, ImpJ, VasE DUF167 PF02594.16 KKK14804.1 - 1.6e-13 50.5 0.5 1.9e-07 31.1 0.0 2.2 2 0 0 2 2 2 2 Uncharacterised ACR, YggU family COG1872 UBA_4 PF14555.6 KKK14805.1 - 6.7e-12 45.0 0.1 1.3e-11 44.1 0.1 1.5 1 0 0 1 1 1 1 UBA-like domain UIM PF02809.20 KKK14805.1 - 0.081 12.9 1.0 0.33 11.0 1.0 2.1 1 0 0 1 1 1 0 Ubiquitin interaction motif FHA PF00498.26 KKK14806.1 - 1.9e-13 50.6 0.0 4.6e-13 49.3 0.0 1.7 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KKK14806.1 - 0.058 13.7 0.0 0.13 12.6 0.0 1.5 1 0 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain Pkinase PF00069.25 KKK14807.1 - 7.5e-73 245.1 0.0 9.8e-73 244.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK14807.1 - 3.6e-36 124.8 0.0 5e-36 124.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase AdenylateSensor PF16579.5 KKK14807.1 - 8e-18 65.0 0.0 4.8e-12 46.4 0.0 2.5 2 0 0 2 2 2 2 Adenylate sensor of SNF1-like protein kinase UBA_2 PF08587.11 KKK14807.1 - 4.3e-13 49.2 0.0 9.5e-13 48.0 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin associated domain (UBA) Kinase-like PF14531.6 KKK14807.1 - 3.9e-06 26.4 0.0 6.6e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 KKK14807.1 - 0.00012 21.8 0.1 0.00023 20.8 0.1 1.4 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 KKK14807.1 - 0.0089 15.0 0.1 0.015 14.3 0.1 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KKK14807.1 - 0.033 13.5 0.1 0.085 12.2 0.1 1.7 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KKK14807.1 - 0.079 12.9 0.1 0.079 12.9 0.1 2.7 2 1 1 3 3 3 0 Phosphotransferase enzyme family YukC PF10140.9 KKK14807.1 - 0.083 11.7 0.1 0.12 11.2 0.1 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC zf-CHY PF05495.12 KKK14808.1 - 0.084 13.4 2.3 0.12 12.9 2.3 1.2 1 0 0 1 1 1 0 CHY zinc finger TFIIB PF00382.19 KKK14809.1 - 6.7e-33 112.6 0.8 1.4e-17 63.5 0.1 2.4 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.13 KKK14809.1 - 1.8e-26 92.4 0.0 1.8e-26 92.4 0.0 2.5 5 0 0 5 5 5 1 Brf1-like TBP-binding domain TF_Zn_Ribbon PF08271.12 KKK14809.1 - 0.00014 21.3 2.0 0.00032 20.2 2.0 1.7 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.23 KKK14809.1 - 0.00062 19.5 0.1 1.1 9.0 0.0 2.3 2 0 0 2 2 2 2 Cyclin, N-terminal domain IBR PF01485.21 KKK14809.1 - 0.085 13.1 1.3 0.19 11.9 1.3 1.5 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain E1-E2_ATPase PF00122.20 KKK14810.1 - 5.5e-50 169.4 0.0 4.5e-49 166.4 0.0 2.2 2 0 0 2 2 2 1 E1-E2 ATPase HMA PF00403.26 KKK14810.1 - 8.1e-47 157.5 2.2 4.4e-11 43.1 0.0 4.4 4 0 0 4 4 4 4 Heavy-metal-associated domain Hydrolase PF00702.26 KKK14810.1 - 3.7e-33 115.6 0.0 5.8e-33 114.9 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KKK14810.1 - 1.1e-05 25.4 0.0 0.0066 16.2 0.0 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 KKK14810.1 - 3.5e-05 24.3 0.0 0.00032 21.1 0.0 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Peptidase_M18 PF02127.15 KKK14823.1 - 1.7e-171 570.8 0.0 2e-171 570.6 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) WD40 PF00400.32 KKK14824.1 - 1.3e-24 85.9 11.5 0.0002 22.1 0.1 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKK14824.1 - 1.3e-12 47.8 4.4 0.0014 18.9 0.3 4.5 4 1 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KKK14824.1 - 1.5e-07 31.5 0.1 0.016 15.1 0.0 3.2 2 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KKK14824.1 - 0.052 12.5 0.0 0.11 11.4 0.0 1.6 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PALB2_WD40 PF16756.5 KKK14824.1 - 0.13 11.2 1.3 4.4 6.1 0.1 2.3 2 0 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain Pyrophosphatase PF00719.19 KKK14825.1 - 2.5e-58 196.4 0.1 3.4e-58 196.0 0.1 1.2 1 0 0 1 1 1 1 Inorganic pyrophosphatase MRP_L53 PF10780.9 KKK14826.1 - 1.2e-05 25.4 3.8 2e-05 24.6 3.8 1.5 1 1 0 1 1 1 1 39S ribosomal protein L53/MRP-L53 DUF1746 PF08508.10 KKK14827.1 - 3.6e-41 140.1 1.3 5.4e-41 139.6 1.3 1.3 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1746) Dus PF01207.17 KKK14828.1 - 2.5e-44 151.6 0.0 8.6e-44 149.9 0.0 1.7 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) HisKA_4TM PF16926.5 KKK14828.1 - 0.14 11.7 0.7 1.2 8.6 0.0 2.2 2 0 0 2 2 2 0 Archaeal 4TM region of histidine kinase PrmA PF06325.13 KKK14828.1 - 0.15 11.4 0.0 0.34 10.3 0.0 1.5 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) RPN7 PF10602.9 KKK14829.1 - 1.9e-52 177.5 0.4 2.9e-52 176.9 0.4 1.3 1 0 0 1 1 1 1 26S proteasome subunit RPN7 Aminotran_1_2 PF00155.21 KKK14829.1 - 1.5e-40 139.5 0.0 2.9e-40 138.5 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II PCI PF01399.27 KKK14829.1 - 2.5e-15 56.9 0.0 8e-15 55.3 0.0 1.9 1 0 0 1 1 1 1 PCI domain PEX11 PF05648.14 KKK14830.1 - 1.8e-73 246.7 0.5 2.1e-73 246.5 0.5 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Mito_carr PF00153.27 KKK14832.1 - 7.3e-53 176.5 2.8 4.7e-19 68.1 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein zf-Nse PF11789.8 KKK14833.1 - 1.3e-23 82.6 0.1 2.2e-23 81.8 0.1 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 KKK14833.1 - 0.00014 21.8 0.1 0.0026 17.8 0.0 2.4 1 1 1 2 2 2 2 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KKK14833.1 - 0.0065 16.3 0.6 0.14 12.1 0.0 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-MIZ PF02891.20 KKK14833.1 - 0.014 15.1 1.7 0.099 12.4 0.1 2.2 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger PPP4R2 PF09184.11 KKK14833.1 - 6.9 6.2 32.0 2 7.9 7.4 2.4 2 0 0 2 2 2 0 PPP4R2 Na_H_Exchanger PF00999.21 KKK14834.1 - 1.1e-42 146.2 15.7 1.4e-42 145.9 15.7 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family YrhC PF14143.6 KKK14834.1 - 0.011 15.8 0.9 0.17 12.0 0.1 3.2 3 0 0 3 3 3 0 YrhC-like protein PEPCK_ATP PF01293.20 KKK14835.1 - 4.6e-216 718.0 0.0 5.5e-216 717.7 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_25 PF13481.6 KKK14835.1 - 0.094 12.3 0.0 1.8 8.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KKK14835.1 - 0.18 12.0 0.1 0.39 10.9 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KKK14835.1 - 0.19 12.1 0.0 0.39 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain 6PF2K PF01591.18 KKK14836.1 - 1.9e-76 256.3 0.2 5.6e-76 254.7 0.0 1.8 2 0 0 2 2 2 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 KKK14836.1 - 8.1e-40 136.6 0.0 1.5e-39 135.7 0.0 1.5 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Vps39_1 PF10366.9 KKK14836.1 - 7.8e-34 116.2 0.0 8.3e-32 109.7 0.0 2.8 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.9 KKK14836.1 - 3.6e-31 107.8 0.5 1.7e-30 105.7 0.0 2.5 4 0 0 4 4 4 1 Vacuolar sorting protein 39 domain 2 CNH PF00780.22 KKK14836.1 - 3.5e-16 59.6 0.0 1.9e-15 57.3 0.0 1.9 1 1 0 1 1 1 1 CNH domain KTI12 PF08433.10 KKK14836.1 - 0.0001 21.9 0.0 0.00021 20.8 0.0 1.5 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.6 KKK14836.1 - 0.00011 22.3 0.0 0.00027 21.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain Clathrin PF00637.20 KKK14836.1 - 0.00083 19.2 0.6 0.00083 19.2 0.6 2.8 3 0 0 3 3 3 1 Region in Clathrin and VPS DinB_2 PF12867.7 KKK14836.1 - 0.066 13.7 0.6 1.8 9.1 0.0 3.1 2 1 1 3 3 3 0 DinB superfamily TPR_1 PF00515.28 KKK14836.1 - 0.34 10.8 1.9 34 4.5 0.9 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Gon7 PF08738.10 KKK14837.1 - 2.2e-13 50.2 0.6 7.6e-13 48.5 0.2 1.7 1 1 1 2 2 2 1 Gon7 family HbrB PF08539.11 KKK14838.1 - 1.5e-50 171.5 0.0 3e-50 170.5 0.0 1.6 1 0 0 1 1 1 1 HbrB-like Myb_DNA-bind_5 PF13873.6 KKK14839.1 - 0.0014 18.7 0.3 0.16 12.0 0.1 2.9 2 1 1 3 3 3 1 Myb/SANT-like DNA-binding domain SOG2 PF10428.9 KKK14839.1 - 0.0018 17.6 6.4 0.0021 17.4 6.4 1.1 1 0 0 1 1 1 1 RAM signalling pathway protein Myb_DNA-bind_3 PF12776.7 KKK14839.1 - 0.0071 17.3 0.2 1.6 9.8 0.0 2.3 1 1 1 2 2 2 2 Myb/SANT-like DNA-binding domain RBR PF17208.3 KKK14839.1 - 0.01 16.5 3.3 0.01 16.5 3.3 2.9 2 1 1 3 3 3 0 RNA binding Region Ribosomal_60s PF00428.19 KKK14839.1 - 6.9 7.3 13.4 0.66 10.6 6.5 2.6 2 0 0 2 2 2 0 60s Acidic ribosomal protein RRM_1 PF00076.22 KKK14840.1 - 5.7e-20 70.9 0.3 1.7e-13 50.2 0.0 3.4 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KKK14840.1 - 0.041 14.0 0.0 0.51 10.5 0.0 2.2 2 0 0 2 2 2 0 RNA recognition motif Limkain-b1 PF11608.8 KKK14840.1 - 0.067 13.3 0.0 4.7 7.4 0.0 2.7 3 0 0 3 3 3 0 Limkain b1 AAA PF00004.29 KKK14841.1 - 1.7e-16 60.8 0.1 5.8e-16 59.1 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KKK14841.1 - 0.00068 19.6 0.0 0.0022 18.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KKK14841.1 - 0.00084 19.6 0.6 0.0091 16.3 0.1 2.6 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 KKK14841.1 - 0.0059 17.0 1.8 0.009 16.4 0.1 2.2 2 1 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.6 KKK14841.1 - 0.031 14.5 1.7 0.18 11.9 0.0 2.9 2 1 0 2 2 2 0 AAA domain AAA_19 PF13245.6 KKK14841.1 - 0.067 13.5 0.0 0.21 11.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain Ribosomal_S7 PF00177.21 KKK14850.1 - 2.2e-35 121.5 1.8 3.2e-35 121.0 1.8 1.2 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e SDA1 PF05285.12 KKK14851.1 - 4e-96 322.5 40.6 4e-96 322.5 40.6 2.9 2 1 0 2 2 2 2 SDA1 NUC130_3NT PF08158.12 KKK14851.1 - 1.1e-09 38.5 2.1 3e-09 37.0 2.1 1.8 1 0 0 1 1 1 1 NUC130/3NT domain DUF4072 PF13284.6 KKK14851.1 - 6.5 7.3 6.9 8.2 7.0 0.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4072) AMP-binding PF00501.28 KKK14852.1 - 3.4e-67 226.9 0.0 1.3e-37 129.5 0.0 3.9 2 2 0 2 2 2 2 AMP-binding enzyme DMAP_binding PF06464.11 KKK14852.1 - 6.5e-10 39.8 0.0 2.2e-09 38.1 0.0 1.8 2 0 0 2 2 2 1 DMAP1-binding Domain GvpG PF05120.12 KKK14852.1 - 0.0027 17.7 0.2 0.0055 16.7 0.2 1.5 1 0 0 1 1 1 1 Gas vesicle protein G DUF4032 PF13224.6 KKK14852.1 - 0.056 13.3 0.2 8.1 6.3 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4032) ATG27 PF09451.10 KKK14853.1 - 4.8e-67 226.6 0.0 5.6e-67 226.4 0.0 1.0 1 0 0 1 1 1 1 Autophagy-related protein 27 Sulfotransfer_3 PF13469.6 KKK14854.1 - 0.0012 19.2 0.3 0.24 11.7 0.0 3.2 2 1 0 2 2 2 1 Sulfotransferase family AAA_2 PF07724.14 KKK14855.1 - 7.7e-46 156.3 0.0 1.9e-44 151.8 0.0 2.8 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 KKK14855.1 - 4.7e-31 106.8 3.8 4.7e-31 106.8 3.8 3.4 3 0 0 3 3 3 1 AAA lid domain AAA PF00004.29 KKK14855.1 - 3.2e-27 95.6 0.0 3.8e-15 56.5 0.0 3.1 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 KKK14855.1 - 8.4e-25 86.6 0.4 3e-24 84.9 0.4 2.1 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 KKK14855.1 - 3.5e-15 56.2 0.0 2.2e-09 37.4 0.0 3.1 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KKK14855.1 - 2.1e-13 50.7 0.0 2.8e-05 24.4 0.0 4.4 2 1 1 3 3 3 2 AAA domain AAA_16 PF13191.6 KKK14855.1 - 2e-12 47.8 12.8 1.4e-06 28.8 0.1 5.8 4 2 1 6 6 5 2 AAA ATPase domain Sigma54_activat PF00158.26 KKK14855.1 - 1.3e-08 34.7 0.0 2.5e-05 24.1 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain Clp_N PF02861.20 KKK14855.1 - 6.2e-07 29.4 3.0 0.00043 20.4 0.1 4.4 4 0 0 4 4 3 1 Clp amino terminal domain, pathogenicity island component IstB_IS21 PF01695.17 KKK14855.1 - 1.6e-06 28.0 0.0 0.084 12.6 0.0 3.1 3 0 0 3 3 2 2 IstB-like ATP binding protein AAA_18 PF13238.6 KKK14855.1 - 1.7e-06 28.6 0.2 0.078 13.5 0.0 3.9 3 0 0 3 3 2 2 AAA domain AAA_14 PF13173.6 KKK14855.1 - 1.7e-06 28.1 0.0 0.12 12.5 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA_7 PF12775.7 KKK14855.1 - 4e-06 26.5 0.0 0.016 14.8 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region Mg_chelatase PF01078.21 KKK14855.1 - 5.6e-06 25.9 0.5 0.19 11.1 0.1 4.2 3 1 0 3 3 3 1 Magnesium chelatase, subunit ChlI TniB PF05621.11 KKK14855.1 - 2.1e-05 24.0 0.2 0.29 10.5 0.0 4.8 4 2 0 4 4 3 1 Bacterial TniB protein AAA_33 PF13671.6 KKK14855.1 - 2.2e-05 24.7 0.3 0.28 11.3 0.0 3.5 3 0 0 3 3 3 2 AAA domain RNA_helicase PF00910.22 KKK14855.1 - 5.5e-05 23.5 0.0 0.5 10.8 0.0 2.7 2 0 0 2 2 2 2 RNA helicase AAA_30 PF13604.6 KKK14855.1 - 0.0001 22.1 0.0 0.95 9.1 0.0 3.4 3 1 0 3 3 2 2 AAA domain RuvB_N PF05496.12 KKK14855.1 - 0.00016 21.5 1.0 1.9 8.2 0.5 4.4 3 1 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_24 PF13479.6 KKK14855.1 - 0.00022 21.0 0.0 0.25 11.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 KKK14855.1 - 0.00028 20.9 0.0 0.3 11.1 0.0 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE RsgA_GTPase PF03193.16 KKK14855.1 - 0.00029 20.8 0.2 0.4 10.6 0.0 3.1 3 0 0 3 3 3 1 RsgA GTPase AAA_28 PF13521.6 KKK14855.1 - 0.00041 20.6 4.5 0.64 10.2 0.0 3.9 3 1 1 4 4 3 2 AAA domain ABC_tran PF00005.27 KKK14855.1 - 0.0005 20.6 3.8 0.67 10.5 0.0 3.8 4 0 0 4 4 3 1 ABC transporter ATPase_2 PF01637.18 KKK14855.1 - 0.00052 20.0 10.2 0.11 12.3 0.3 4.8 5 1 0 5 5 3 1 ATPase domain predominantly from Archaea AAA_3 PF07726.11 KKK14855.1 - 0.00065 19.6 0.0 1.9 8.3 0.0 3.3 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 KKK14855.1 - 0.0016 18.8 0.0 0.49 10.7 0.0 3.3 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 KKK14855.1 - 0.0018 17.4 0.0 0.015 14.3 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_29 PF13555.6 KKK14855.1 - 0.002 17.8 0.0 1.9 8.3 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain Roc PF08477.13 KKK14855.1 - 0.0021 18.3 0.0 0.93 9.7 0.0 2.8 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase NACHT PF05729.12 KKK14855.1 - 0.0079 16.1 0.0 0.45 10.4 0.0 2.5 2 0 0 2 2 2 1 NACHT domain Zeta_toxin PF06414.12 KKK14855.1 - 0.0082 15.4 0.2 0.89 8.8 0.0 2.9 3 0 0 3 3 2 1 Zeta toxin AAA_25 PF13481.6 KKK14855.1 - 0.0095 15.5 0.2 2 8.0 0.0 3.1 2 1 0 2 2 2 1 AAA domain NTPase_1 PF03266.15 KKK14855.1 - 0.011 15.7 0.0 0.31 10.9 0.0 2.9 3 0 0 3 3 2 0 NTPase ResIII PF04851.15 KKK14855.1 - 0.018 15.0 0.0 3.7 7.5 0.0 3.6 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit Torsin PF06309.11 KKK14855.1 - 0.028 14.5 0.0 0.097 12.8 0.0 1.8 2 0 0 2 2 1 0 Torsin SRP54 PF00448.22 KKK14855.1 - 0.034 13.8 0.0 8.3 6.0 0.0 2.8 3 0 0 3 3 2 0 SRP54-type protein, GTPase domain AAA_15 PF13175.6 KKK14855.1 - 0.037 13.8 0.6 34 4.0 0.0 3.4 3 0 0 3 3 3 0 AAA ATPase domain Rad17 PF03215.15 KKK14855.1 - 0.059 13.3 0.0 12 5.7 0.0 2.9 2 1 0 3 3 2 0 Rad17 P-loop domain ATP_bind_1 PF03029.17 KKK14855.1 - 0.11 12.3 0.1 21 4.8 0.0 3.1 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein AAA_23 PF13476.6 KKK14855.1 - 0.22 12.0 0.0 0.22 12.0 0.0 4.6 4 2 0 5 5 2 0 AAA domain MPS2 PF17060.5 KKK14855.1 - 0.59 9.3 9.9 0.015 14.6 2.7 1.9 2 0 0 2 2 2 0 Monopolar spindle protein 2 DHR10 PF18595.1 KKK14855.1 - 0.73 9.9 19.4 1.6 8.8 13.8 3.1 2 1 0 2 2 1 0 Designed helical repeat protein 10 domain SbcD_C PF12320.8 KKK14855.1 - 3.1 8.1 9.7 21 5.5 0.3 3.6 3 0 0 3 3 2 0 Type 5 capsule protein repressor C-terminal domain V_ATPase_I PF01496.19 KKK14855.1 - 3.5 5.4 9.5 0.26 9.2 4.9 1.4 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Macoilin PF09726.9 KKK14855.1 - 9.6 4.6 10.8 19 3.6 10.8 1.4 1 0 0 1 1 1 0 Macoilin family SNF2_N PF00176.23 KKK14856.1 - 1.4e-57 195.0 0.0 2.2e-57 194.4 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KKK14856.1 - 4.9e-15 55.8 0.0 1.6e-14 54.1 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KKK14856.1 - 9.7e-09 35.5 0.0 2.3e-08 34.2 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF5473 PF17567.2 KKK14856.1 - 0.04 14.2 6.0 3 8.2 1.1 2.8 2 0 0 2 2 2 0 Family of unknown function (DUF5473) Ribosomal_60s PF00428.19 KKK14856.1 - 0.36 11.5 4.0 1.1 9.8 4.0 1.9 1 0 0 1 1 1 0 60s Acidic ribosomal protein EMC3_TMCO1 PF01956.16 KKK14858.1 - 1.8 8.3 6.9 8.1 6.1 0.8 2.6 2 1 1 3 3 3 0 Integral membrane protein EMC3/TMCO1-like AA_permease_2 PF13520.6 KKK14859.1 - 2.1e-46 158.6 51.2 2.5e-46 158.4 51.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KKK14859.1 - 8.5e-22 77.4 42.5 1.2e-21 76.9 42.5 1.1 1 0 0 1 1 1 1 Amino acid permease Phospholamban PF04272.14 KKK14859.1 - 1.7 8.2 0.0 1.7 8.2 0.0 4.2 5 0 0 5 5 5 0 Phospholamban Tubulin_3 PF14881.6 KKK14860.1 - 2.9e-84 281.2 0.0 8e-84 279.8 0.0 1.8 1 0 0 1 1 1 1 Tubulin domain HSP70 PF00012.20 KKK14860.1 - 1e-59 202.3 3.3 3.5e-58 197.2 0.1 3.1 3 0 0 3 3 3 2 Hsp70 protein Misat_Tub_SegII PF10644.9 KKK14860.1 - 1.4e-22 80.2 0.0 1.4e-22 80.2 0.0 3.5 4 0 0 4 4 4 1 Misato Segment II tubulin-like domain DUF2201_N PF13203.6 KKK14860.1 - 0.32 10.5 4.8 0.66 9.5 4.8 1.4 1 0 0 1 1 1 0 Putative metallopeptidase domain SlyX PF04102.12 KKK14860.1 - 6.5 7.5 6.5 1.5 9.5 0.5 3.1 2 1 0 2 2 2 0 SlyX RNR_inhib PF08591.10 KKK14861.1 - 4.3e-20 73.0 0.1 7.5e-20 72.2 0.1 1.4 1 0 0 1 1 1 1 Ribonucleotide reductase inhibitor DUF2347 PF09804.9 KKK14862.1 - 2.2e-105 352.3 0.0 4.3e-105 351.4 0.0 1.5 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2347) DUF4484 PF14831.6 KKK14862.1 - 5.2e-63 212.9 0.0 8.5e-63 212.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4484) Avl9 PF09794.9 KKK14862.1 - 0.012 14.3 0.0 3.5 6.2 0.0 2.4 2 1 0 2 2 2 0 Transport protein Avl9 HNF-1_N PF04814.13 KKK14862.1 - 1.2 9.7 4.4 0.18 12.4 0.6 1.5 2 0 0 2 2 2 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus Afi1 PF07792.12 KKK14862.1 - 2.3 8.7 4.8 17 5.9 0.0 3.2 4 0 0 4 4 4 0 Docking domain of Afi1 for Arf3 in vesicle trafficking GP3_package PF16677.5 KKK14863.1 - 0.078 13.1 0.7 0.2 11.8 0.1 2.0 2 0 0 2 2 2 0 DNA-packaging protein gp3 Pkinase PF00069.25 KKK14886.1 - 5.2e-63 212.9 0.0 7.5e-63 212.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK14886.1 - 5.5e-35 120.9 0.0 8.3e-35 120.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 KKK14886.1 - 9.6e-17 60.5 0.4 1.7e-16 59.7 0.4 1.4 1 0 0 1 1 1 1 Kinase associated domain 1 Haspin_kinase PF12330.8 KKK14886.1 - 4.4e-05 22.6 0.1 6.2e-05 22.1 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KKK14886.1 - 4.7e-05 22.8 0.0 7.3e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KKK14886.1 - 0.00016 21.1 0.1 0.00028 20.3 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KKK14886.1 - 0.0052 16.7 0.0 0.013 15.5 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 KKK14886.1 - 0.02 14.5 0.1 0.043 13.4 0.1 1.5 1 0 0 1 1 1 0 RIO1 family YrbL-PhoP_reg PF10707.9 KKK14886.1 - 0.071 12.6 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Fungal_trans PF04082.18 KKK14892.1 - 5.6e-43 146.9 0.0 9.1e-43 146.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK14892.1 - 5.4e-08 32.8 7.9 1.1e-07 31.9 7.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PHD PF00628.29 KKK14892.1 - 0.0034 17.3 4.0 0.0068 16.3 4.0 1.5 1 0 0 1 1 1 1 PHD-finger RTA1 PF04479.13 KKK14893.1 - 3.9e-56 189.9 15.1 3.6e-55 186.8 15.1 1.9 1 1 0 1 1 1 1 RTA1 like protein Cyclin_N PF00134.23 KKK14893.1 - 0.11 12.2 0.5 0.21 11.4 0.5 1.4 1 0 0 1 1 1 0 Cyclin, N-terminal domain Ribosomal_L30_N PF08079.12 KKK14894.1 - 7e-27 93.5 16.3 1.3e-26 92.7 16.3 1.4 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.20 KKK14894.1 - 7.8e-16 57.7 1.8 7.8e-16 57.7 1.8 1.8 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e TFB6 PF17110.5 KKK14894.1 - 0.35 10.6 1.8 0.63 9.8 1.3 1.6 2 0 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH EAP30 PF04157.16 KKK14895.1 - 6.8e-71 238.3 0.1 7.7e-71 238.1 0.1 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family MarR_2 PF12802.7 KKK14895.1 - 0.12 12.3 0.2 0.48 10.3 0.0 2.1 2 0 0 2 2 2 0 MarR family PRK PF00485.18 KKK14896.1 - 0.0013 18.5 0.0 0.0023 17.7 0.0 1.4 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family SRP_SPB PF02978.19 KKK14896.1 - 0.061 14.0 0.0 0.11 13.1 0.0 1.4 1 0 0 1 1 1 0 Signal peptide binding domain AAA_16 PF13191.6 KKK14896.1 - 0.078 13.4 0.0 0.42 11.0 0.0 2.1 2 1 0 2 2 2 0 AAA ATPase domain Ysc84 PF04366.12 KKK14897.1 - 1e-47 161.1 0.0 1.9e-47 160.2 0.0 1.5 1 0 0 1 1 1 1 Las17-binding protein actin regulator Peptidase_S10 PF00450.22 KKK14898.1 - 5.8e-86 289.5 1.6 7.8e-86 289.1 1.6 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase DnaJ_C PF01556.18 KKK14899.1 - 1.5e-35 122.5 0.4 1.9e-35 122.2 0.4 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KKK14899.1 - 1.5e-27 95.5 5.2 2.4e-27 94.8 5.2 1.3 1 0 0 1 1 1 1 DnaJ domain PIG-X PF08320.12 KKK14900.1 - 6.9e-74 248.3 0.0 9.6e-74 247.8 0.0 1.2 1 0 0 1 1 1 1 PIG-X / PBN1 Dsl1_N PF11988.8 KKK14900.1 - 0.3 10.0 0.0 0.43 9.5 0.0 1.1 1 0 0 1 1 1 0 Retrograde transport protein Dsl1 N terminal DegS PF05384.11 KKK14901.1 - 0.17 11.4 0.2 0.25 10.8 0.2 1.2 1 0 0 1 1 1 0 Sensor protein DegS APH PF01636.23 KKK14902.1 - 2.6e-11 43.9 0.0 5.8e-10 39.5 0.0 2.6 2 1 0 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.20 KKK14902.1 - 0.0017 17.7 0.0 0.0028 17.0 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase DUF4034 PF13226.6 KKK14903.1 - 0.0084 15.5 0.0 0.0093 15.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4034) CoA_trans PF01144.23 KKK14904.1 - 1.2e-94 315.8 4.2 7.2e-53 179.2 0.6 2.0 2 0 0 2 2 2 2 Coenzyme A transferase DUF531 PF04407.12 KKK14904.1 - 0.033 14.3 0.0 0.15 12.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF531) Tim17 PF02466.19 KKK14906.1 - 4.2e-07 30.3 8.9 8.3e-07 29.4 8.1 1.9 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family RPT PF13446.6 KKK14907.1 - 1.5e-49 165.7 1.8 9.2e-20 70.3 0.0 4.6 4 0 0 4 4 4 4 A repeated domain in UCH-protein UCH PF00443.29 KKK14907.1 - 7.8e-43 146.8 0.0 1.5e-42 145.9 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KKK14907.1 - 0.0021 17.7 0.2 0.014 15.0 0.0 2.2 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase E7 PF00527.18 KKK14907.1 - 0.051 13.8 0.0 0.31 11.2 0.0 2.4 1 0 0 1 1 1 0 E7 protein, Early protein Pkinase PF00069.25 KKK14908.1 - 4.3e-65 219.7 0.0 6.1e-65 219.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK14908.1 - 2.6e-29 102.3 0.0 4.1e-29 101.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KKK14908.1 - 0.0062 15.5 0.0 0.011 14.7 0.0 1.4 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KKK14908.1 - 0.019 14.3 0.0 0.035 13.4 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KKK14908.1 - 0.055 13.4 0.4 0.17 11.8 0.0 1.9 3 0 0 3 3 3 0 Phosphotransferase enzyme family p450 PF00067.22 KKK14909.1 - 3.1e-55 187.7 0.0 4.2e-55 187.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF2370 PF10176.9 KKK14911.1 - 2.7e-87 292.2 0.0 4.9e-87 291.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2370) Abhydrolase_6 PF12697.7 KKK14912.1 - 1.6e-11 45.3 0.0 2.2e-11 44.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KKK14912.1 - 2.1e-10 40.7 0.0 3.5e-10 40.0 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KKK14912.1 - 1.1e-05 24.9 0.0 1.4e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 KKK14912.1 - 0.00032 20.9 0.1 0.00069 19.8 0.1 1.6 1 1 0 1 1 1 1 Thioesterase domain tRNA-synt_2b PF00587.25 KKK14914.1 - 1.8e-30 106.2 0.0 9.9e-28 97.3 0.0 2.7 2 0 0 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 KKK14914.1 - 8.2e-17 61.1 0.2 1.7e-16 60.1 0.2 1.6 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.14 KKK14914.1 - 1.2e-13 50.9 0.0 2.4e-13 49.9 0.0 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.21 KKK14914.1 - 0.00014 21.8 0.0 0.00028 20.8 0.0 1.5 1 0 0 1 1 1 1 TGS domain DUF604 PF04646.12 KKK14915.1 - 3.8e-14 52.7 0.4 8.9e-14 51.5 0.4 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF604 CDP-OH_P_transf PF01066.21 KKK14916.1 - 4e-11 43.5 0.1 4e-11 43.5 0.1 2.2 3 0 0 3 3 3 1 CDP-alcohol phosphatidyltransferase Gar1 PF04410.14 KKK14917.1 - 8.9e-40 136.0 0.0 1.1e-39 135.7 0.0 1.0 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region DUF1752 PF08550.10 KKK14930.1 - 0.00013 21.7 0.1 0.00026 20.8 0.1 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) PRIMA1 PF16101.5 KKK14930.1 - 0.59 10.2 7.4 1.3 9.0 3.0 2.6 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 adh_short_C2 PF13561.6 KKK14931.1 - 9.5e-54 182.4 0.0 1.5e-53 181.8 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KKK14931.1 - 7.6e-38 129.9 0.1 1.2e-37 129.3 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KKK14931.1 - 4.8e-13 49.4 0.1 7.8e-13 48.7 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KKK14931.1 - 0.0072 15.8 0.1 0.013 15.0 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Pyr_redox_2 PF07992.14 KKK14931.1 - 0.014 14.7 0.0 0.02 14.1 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GDP_Man_Dehyd PF16363.5 KKK14931.1 - 0.028 13.8 0.1 1.6 8.0 0.0 2.1 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase DUF2841 PF11001.8 KKK14932.1 - 3e-48 163.0 0.9 4.4e-48 162.4 0.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) Fungal_trans PF04082.18 KKK14933.1 - 1e-09 37.9 0.0 1.6e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DnaJ PF00226.31 KKK14967.1 - 8.2e-20 70.7 0.6 2.3e-19 69.3 0.6 1.8 1 0 0 1 1 1 1 DnaJ domain RRM_1 PF00076.22 KKK14967.1 - 0.026 14.3 0.1 0.083 12.7 0.1 1.9 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) adh_short PF00106.25 KKK14969.1 - 5.2e-10 39.1 0.1 5.2e-10 39.1 0.1 2.0 2 1 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KKK14969.1 - 1.4e-07 31.3 0.3 4.7e-07 29.6 0.3 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DIOX_N PF14226.6 KKK14970.1 - 1.9e-27 96.3 0.0 3e-27 95.7 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KKK14970.1 - 1.5e-15 57.5 0.0 3.1e-15 56.5 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Prominin PF05478.11 KKK14970.1 - 0.18 9.7 0.0 0.26 9.2 0.0 1.1 1 0 0 1 1 1 0 Prominin Amidohydro_2 PF04909.14 KKK14971.1 - 1.3e-30 107.1 0.3 2.5e-30 106.2 0.3 1.4 1 1 0 1 1 1 1 Amidohydrolase TatD_DNase PF01026.21 KKK14971.1 - 0.007 15.8 0.0 0.015 14.6 0.0 1.5 1 0 0 1 1 1 1 TatD related DNase Homez PF11569.8 KKK14972.1 - 0.079 12.4 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez NACHT_N PF17100.5 KKK14972.1 - 1.2 8.9 7.3 0.62 9.9 3.0 2.6 4 0 0 4 4 4 0 N-terminal domain of NWD NACHT-NTPase R3H-assoc PF13902.6 KKK14972.1 - 2.2 8.7 5.7 1.9 8.9 1.2 2.6 2 1 0 2 2 2 0 R3H-associated N-terminal domain MeMO_Hyd_G PF02964.16 KKK14973.1 - 0.0032 17.5 0.1 0.0049 16.9 0.1 1.2 1 0 0 1 1 1 1 Methane monooxygenase, hydrolase gamma chain AMP-binding PF00501.28 KKK14974.1 - 1.3e-64 218.3 0.0 1.8e-64 217.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KKK14974.1 - 1.4e-15 58.1 0.0 3.6e-15 56.7 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain SdpI PF13630.6 KKK14975.1 - 0.047 13.8 0.1 0.047 13.8 0.1 2.8 2 1 1 3 3 3 0 SdpI/YhfL protein family GpcrRhopsn4 PF10192.9 KKK14975.1 - 0.061 12.7 5.1 0.12 11.7 5.1 1.4 1 0 0 1 1 1 0 Rhodopsin-like GPCR transmembrane domain SapB_2 PF03489.17 KKK14975.1 - 0.12 12.5 0.2 18 5.6 0.0 2.5 2 0 0 2 2 2 0 Saposin-like type B, region 2 LDB19 PF13002.7 KKK14976.1 - 6.6e-59 198.9 0.0 1.1e-58 198.2 0.0 1.3 1 0 0 1 1 1 1 Arrestin_N terminal like Arrestin_N PF00339.29 KKK14976.1 - 1e-08 35.3 0.0 2.5e-08 34.1 0.0 1.7 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain SASRP1 PF15160.6 KKK14976.1 - 1.8 8.2 9.9 0.5 10.0 5.4 2.0 2 0 0 2 2 2 0 Spermatogenesis-associated serine-rich protein 1 MRC1 PF09444.10 KKK14981.1 - 2.6e-22 79.9 22.7 2.6e-22 79.9 22.7 7.9 7 1 0 7 7 7 1 MRC1-like domain BUD22 PF09073.10 KKK14981.1 - 0.00037 20.0 18.8 0.00037 20.0 18.8 5.9 3 2 2 5 5 5 1 BUD22 Nuc_deoxyri_tr3 PF11071.8 KKK14981.1 - 0.1 12.7 0.2 0.26 11.4 0.2 1.6 1 0 0 1 1 1 0 Nucleoside 2-deoxyribosyltransferase YtoQ KR PF08659.10 KKK14981.1 - 0.48 10.3 4.7 2.1 8.2 1.1 2.5 2 0 0 2 2 2 0 KR domain COQ7 PF03232.13 KKK14982.1 - 3.8e-70 235.1 0.7 4.5e-70 234.9 0.7 1.1 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Rubrerythrin PF02915.17 KKK14982.1 - 8.3e-06 26.2 0.2 8.3e-05 23.0 0.0 2.0 1 1 1 2 2 2 1 Rubrerythrin Crr6 PF08847.11 KKK14982.1 - 0.0057 16.3 0.1 0.25 11.0 0.0 2.2 1 1 1 2 2 2 2 Chlororespiratory reduction 6 DUF4455 PF14643.6 KKK14982.1 - 0.034 12.8 0.2 0.051 12.2 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4455) SPT2 PF08243.11 KKK14982.1 - 0.1 13.1 4.7 0.17 12.4 4.7 1.3 1 0 0 1 1 1 0 SPT2 chromatin protein Plus-3 PF03126.18 KKK14983.1 - 3.7e-32 111.1 0.0 4.2e-31 107.7 0.0 2.5 2 0 0 2 2 2 1 Plus-3 domain Pkinase PF00069.25 KKK14984.1 - 1e-29 103.7 0.0 8.7e-14 51.5 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KKK14984.1 - 3.5e-07 29.8 0.0 0.0091 15.3 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 KKK14984.1 - 0.04 13.8 0.1 0.13 12.1 0.1 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family LMWPc PF01451.21 KKK14985.1 - 5.2e-33 114.4 0.0 6.9e-33 114.0 0.0 1.2 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase TMEM234 PF10639.9 KKK14986.1 - 1.8e-25 89.2 1.0 2.5e-25 88.8 1.0 1.1 1 0 0 1 1 1 1 Putative transmembrane family 234 PRIMA1 PF16101.5 KKK14986.1 - 0.0058 16.7 6.2 0.012 15.6 6.2 1.6 1 0 0 1 1 1 1 Proline-rich membrane anchor 1 CAP_N PF01213.19 KKK14986.1 - 1.3 8.5 8.7 1.6 8.1 8.7 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg PF05308.11 KKK14986.1 - 1.7 8.7 7.0 2.4 8.2 7.0 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator AF-4 PF05110.13 KKK14986.1 - 5.6 4.9 8.5 7.1 4.6 8.5 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Chitin_synth_1 PF01644.17 KKK14987.1 - 2.4e-75 252.0 0.0 3.8e-75 251.3 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 KKK14987.1 - 3.6e-29 100.5 0.0 7.3e-29 99.5 0.0 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 KKK14987.1 - 2.5e-21 75.9 2.3 2.6e-17 62.6 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase DUF4199 PF13858.6 KKK14987.1 - 5.5 7.4 21.7 0.18 12.2 14.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF4199) Ank_2 PF12796.7 KKK14988.1 - 3.5e-28 98.0 0.9 2.8e-12 47.1 0.0 4.8 3 2 2 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KKK14988.1 - 2.7e-23 82.0 3.1 3.5e-10 40.2 0.1 6.3 5 2 2 7 7 7 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KKK14988.1 - 5.3e-18 63.2 0.9 2e-05 24.6 0.1 7.9 8 0 0 8 8 8 2 Ankyrin repeat Ank_5 PF13857.6 KKK14988.1 - 2.7e-14 53.0 0.9 1.2e-07 31.8 0.1 4.6 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 KKK14988.1 - 1.3e-11 44.4 4.1 2.8e-05 24.4 0.1 4.8 5 0 0 5 5 5 2 Ankyrin repeat MFS_MOT1 PF16983.5 KKK14989.1 - 9.9e-59 196.6 37.8 6.8e-33 113.4 11.1 2.8 3 0 0 3 3 3 2 Molybdate transporter of MFS superfamily Sulfate_transp PF00916.20 KKK14989.1 - 0.013 14.2 24.5 42 2.7 24.5 3.2 1 1 0 1 1 1 0 Sulfate permease family Mlf1IP PF10248.9 KKK14990.1 - 2.4 8.1 6.9 1.1 9.3 3.4 1.9 2 0 0 2 2 2 0 Myelodysplasia-myeloid leukemia factor 1-interacting protein PhyH PF05721.13 KKK14991.1 - 5.1e-44 151.1 0.0 2e-43 149.1 0.0 1.8 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) UTP15_C PF09384.10 KKK14992.1 - 2.7e-52 176.4 1.0 4.7e-52 175.6 1.0 1.4 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.32 KKK14992.1 - 1.3e-20 73.3 5.9 0.00015 22.5 0.0 5.4 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKK14992.1 - 1.6e-09 37.9 0.7 0.01 16.1 0.0 5.0 4 2 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain RAB3GAP2_N PF14655.6 KKK14992.1 - 0.091 12.0 0.4 2.4 7.3 0.1 2.2 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus CCDC-167 PF15188.6 KKK14992.1 - 0.096 13.0 2.3 0.24 11.8 2.3 1.6 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 PVL_ORF50 PF07768.11 KKK14992.1 - 0.11 12.8 2.3 0.31 11.4 2.3 1.7 1 0 0 1 1 1 0 PVL ORF-50-like family Cupin_8 PF13621.6 KKK14993.1 - 2.6e-25 89.6 0.0 4.5e-25 88.8 0.0 1.3 1 1 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 KKK14993.1 - 0.0051 16.3 0.1 0.0098 15.4 0.1 1.4 1 0 0 1 1 1 1 Cupin superfamily protein Cupin_2 PF07883.11 KKK14993.1 - 0.011 15.4 0.0 0.041 13.6 0.0 1.9 2 0 0 2 2 2 0 Cupin domain CK_II_beta PF01214.18 KKK14994.1 - 9.1e-78 260.2 0.0 2.7e-77 258.7 0.0 1.7 1 1 0 1 1 1 1 Casein kinase II regulatory subunit PknG_rubred PF16919.5 KKK14994.1 - 0.19 11.9 1.3 0.36 11.0 0.1 2.0 2 0 0 2 2 2 0 Protein kinase G rubredoxin domain Spt5_N PF11942.8 KKK14994.1 - 0.2 12.7 10.8 0.14 13.2 6.3 2.3 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal RRN3 PF05327.11 KKK14994.1 - 0.39 9.2 0.9 0.51 8.8 0.9 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CENP-B_dimeris PF09026.10 KKK14994.1 - 0.76 10.2 8.8 2.2 8.7 8.7 1.8 2 0 0 2 2 2 0 Centromere protein B dimerisation domain DUF3439 PF11921.8 KKK14994.1 - 1.4 8.9 6.1 2.3 8.2 6.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) DUF4637 PF15470.6 KKK14994.1 - 3.2 7.5 12.2 0.49 10.1 4.6 3.0 3 1 0 3 3 3 0 Domain of unknown function (DUF4637) DNA_pol_phi PF04931.13 KKK14994.1 - 7 4.6 5.4 9.6 4.2 5.4 1.1 1 0 0 1 1 1 0 DNA polymerase phi Rad10 PF03834.14 KKK14995.1 - 5.5e-46 155.3 0.1 8.2e-46 154.7 0.1 1.3 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH PF00633.23 KKK14995.1 - 0.00061 19.5 0.0 0.0013 18.5 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_5 PF14520.6 KKK14995.1 - 0.00063 20.3 0.0 0.0013 19.3 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix domain ssDNA_DBD PF18333.1 KKK14995.1 - 0.07 13.2 0.2 0.14 12.3 0.2 1.5 1 0 0 1 1 1 0 Non-canonical single-stranded DNA-binding domain HHH_2 PF12826.7 KKK14995.1 - 0.16 12.1 0.0 0.3 11.2 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix motif CYSTM PF12734.7 KKK14995.1 - 0.62 10.4 2.0 66 3.9 0.0 2.6 2 0 0 2 2 2 0 Cysteine-rich TM module stress tolerance Fungal_trans_2 PF11951.8 KKK14996.1 - 1.2e-12 47.4 1.0 2.6e-12 46.3 0.1 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Apc15p PF05841.11 KKK14996.1 - 3.6 8.4 7.2 0.16 12.8 0.8 2.0 3 0 0 3 3 3 0 Apc15p protein Cyt-b5 PF00173.28 KKK14997.1 - 3.9e-08 33.3 0.0 4.4e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain bZIP_1 PF00170.21 KKK14998.1 - 0.00026 21.0 6.4 0.00039 20.4 6.4 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KKK14998.1 - 0.002 18.2 7.4 0.0032 17.5 7.4 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 KKK14998.1 - 0.039 14.5 4.9 0.065 13.8 4.9 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor RRM_1 PF00076.22 KKK14999.1 - 2.3e-50 168.3 0.0 8.7e-17 60.7 0.0 5.6 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KKK14999.1 - 1.6e-05 24.8 5.4 0.003 17.6 1.8 3.7 3 0 0 3 3 3 1 RNA binding motif PHM7_cyt PF14703.6 KKK14999.1 - 3.4e-05 24.2 3.0 16 5.6 0.0 6.0 4 3 1 5 5 5 1 Cytosolic domain of 10TM putative phosphate transporter RRM_7 PF16367.5 KKK14999.1 - 0.00017 21.6 0.0 3.3 7.9 0.0 4.0 3 0 0 3 3 3 2 RNA recognition motif RRM_Rrp7 PF17799.1 KKK14999.1 - 0.0018 18.1 0.1 1.1 9.0 0.0 3.3 2 1 1 3 3 3 2 Rrp7 RRM-like N-terminal domain Nup35_RRM_2 PF14605.6 KKK14999.1 - 0.0054 16.7 0.0 0.55 10.3 0.0 2.5 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif CDC45 PF02724.14 KKK14999.1 - 1.4 7.2 29.7 0.035 12.4 13.2 2.5 2 0 0 2 2 2 0 CDC45-like protein AA_permease PF00324.21 KKK15000.1 - 3.4e-106 355.7 37.0 5.9e-100 335.1 24.4 2.0 2 0 0 2 2 2 2 Amino acid permease AA_permease_2 PF13520.6 KKK15000.1 - 5.1e-19 68.4 24.8 5.1e-19 68.4 24.8 1.9 2 0 0 2 2 2 1 Amino acid permease DUF1772 PF08592.11 KKK15000.1 - 0.0073 16.6 1.6 0.0073 16.6 1.6 3.5 3 1 0 3 3 3 1 Domain of unknown function (DUF1772) Fungal_trans PF04082.18 KKK15001.1 - 6.6e-18 64.7 0.0 1.3e-17 63.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK15001.1 - 1.9e-06 27.9 14.2 3.1e-06 27.2 14.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HalX PF08663.10 KKK15001.1 - 0.14 12.4 0.1 0.29 11.5 0.1 1.4 1 0 0 1 1 1 0 HalX domain Amidohydro_1 PF01979.20 KKK15002.1 - 4.1e-75 253.2 1.9 7.6e-75 252.4 1.9 1.4 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.20 KKK15002.1 - 4e-57 191.8 0.7 7.5e-57 190.9 0.7 1.5 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Urease_beta PF00699.20 KKK15002.1 - 3e-41 139.4 0.1 7.8e-41 138.1 0.0 1.8 2 0 0 2 2 2 1 Urease beta subunit Urease_gamma PF00547.18 KKK15002.1 - 9e-39 131.8 0.2 3.7e-38 129.8 0.1 2.2 2 0 0 2 2 2 1 Urease, gamma subunit HMG_box PF00505.19 KKK15002.1 - 7.9e-10 39.0 1.7 7.9e-10 39.0 1.7 2.3 2 0 0 2 2 2 1 HMG (high mobility group) box Amidohydro_3 PF07969.11 KKK15002.1 - 3.5e-09 36.7 0.2 1.7e-06 27.8 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family HMG_box_2 PF09011.10 KKK15002.1 - 0.00049 20.6 0.6 0.0014 19.1 0.6 1.9 1 0 0 1 1 1 1 HMG-box domain DUF2052 PF09747.9 KKK15002.1 - 2 8.5 16.8 3.9 7.5 16.8 1.4 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) CDC45 PF02724.14 KKK15002.1 - 3 6.0 16.3 4.7 5.4 16.3 1.2 1 0 0 1 1 1 0 CDC45-like protein Lactamase_B_2 PF12706.7 KKK15003.1 - 1.4e-07 31.2 0.0 3e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DRMBL PF07522.14 KKK15003.1 - 0.0037 17.4 0.0 0.015 15.5 0.0 2.0 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B PF00753.27 KKK15003.1 - 0.012 15.6 0.0 0.041 13.9 0.0 2.0 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily NPR2 PF06218.11 KKK15004.1 - 3.2e-138 461.2 0.1 2.6e-137 458.2 0.1 2.3 1 1 0 1 1 1 1 Nitrogen permease regulator 2 LRR19-TM PF15176.6 KKK15004.1 - 0.25 11.4 4.7 0.53 10.3 4.7 1.5 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain SelP_N PF04592.14 KKK15004.1 - 0.95 8.8 8.1 1.6 8.1 8.1 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region zf-RING_2 PF13639.6 KKK15006.1 - 2.1e-11 44.0 4.8 3.4e-11 43.3 4.8 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KKK15006.1 - 9.1e-10 38.1 1.7 1.7e-09 37.2 1.7 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KKK15006.1 - 5.7e-08 32.5 5.4 1e-07 31.7 5.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KKK15006.1 - 7.5e-06 25.9 0.9 7.5e-06 25.9 0.9 2.0 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KKK15006.1 - 1e-05 25.3 3.6 1.7e-05 24.5 3.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KKK15006.1 - 2.3e-05 24.3 2.5 3.7e-05 23.6 2.5 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 KKK15006.1 - 0.00017 21.8 4.7 0.00082 19.6 4.7 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 KKK15006.1 - 0.00066 19.5 2.4 0.0011 18.8 2.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KKK15006.1 - 0.0013 18.5 4.5 0.003 17.4 4.5 1.5 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 TMEM154 PF15102.6 KKK15006.1 - 0.011 15.6 0.7 0.039 13.8 0.0 2.0 2 0 0 2 2 2 0 TMEM154 protein family BPD_transp_1 PF00528.22 KKK15006.1 - 0.046 13.4 0.0 0.065 13.0 0.0 1.2 1 0 0 1 1 1 0 Binding-protein-dependent transport system inner membrane component DUF3377 PF11857.8 KKK15006.1 - 0.047 13.6 0.1 0.1 12.5 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) DUF4389 PF14333.6 KKK15006.1 - 0.058 13.3 0.5 0.11 12.4 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4389) zf-C3H2C3 PF17122.5 KKK15006.1 - 0.059 13.4 1.3 0.14 12.2 1.3 1.6 1 0 0 1 1 1 0 Zinc-finger zf-ANAPC11 PF12861.7 KKK15006.1 - 0.078 13.0 1.1 0.18 11.9 1.1 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger PHD PF00628.29 KKK15006.1 - 0.083 12.8 2.9 0.15 11.9 2.9 1.5 1 0 0 1 1 1 0 PHD-finger Zn_ribbon_17 PF17120.5 KKK15006.1 - 0.25 11.0 2.9 0.46 10.1 2.9 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Orf78 PF06024.12 KKK15006.1 - 0.31 11.3 1.0 0.63 10.4 0.0 1.9 2 0 0 2 2 2 0 Orf78 (ac78) zf-RING-like PF08746.11 KKK15006.1 - 0.36 11.2 2.2 0.76 10.1 2.1 1.6 1 1 0 1 1 1 0 RING-like domain zf-C3HC4_4 PF15227.6 KKK15006.1 - 0.56 10.4 4.8 1.4 9.1 4.8 1.7 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Ada3 PF10198.9 KKK15007.1 - 7.1e-51 171.8 0.2 7.1e-51 171.8 0.2 2.1 2 1 0 2 2 2 1 Histone acetyltransferases subunit 3 HA2 PF04408.23 KKK15008.1 - 1.1e-23 83.5 0.1 1.1e-23 83.5 0.1 2.5 3 0 0 3 3 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KKK15008.1 - 2.5e-20 72.6 0.0 5.2e-20 71.6 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KKK15008.1 - 4.6e-13 49.5 0.0 1.1e-12 48.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain S1 PF00575.23 KKK15008.1 - 3.4e-10 40.1 1.4 6.9e-10 39.1 1.4 1.5 1 0 0 1 1 1 1 S1 RNA binding domain AAA_22 PF13401.6 KKK15008.1 - 0.0001 22.6 0.0 0.00026 21.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 KKK15008.1 - 0.00055 19.7 0.1 0.0015 18.3 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase T2SSE PF00437.20 KKK15008.1 - 0.00085 18.5 0.0 0.0021 17.2 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_30 PF13604.6 KKK15008.1 - 0.0023 17.7 0.0 0.0057 16.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KKK15008.1 - 0.017 15.5 0.0 0.036 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KKK15008.1 - 0.088 13.2 0.0 0.32 11.4 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 KKK15008.1 - 0.2 12.1 0.4 3.6 8.1 0.2 2.6 1 1 0 2 2 2 0 ABC transporter RGS PF00615.19 KKK15011.1 - 6.4e-12 45.8 0.0 9.9e-12 45.2 0.0 1.2 1 0 0 1 1 1 1 Regulator of G protein signaling domain DUF647 PF04884.14 KKK15012.1 - 3.1e-107 357.7 4.0 4.1e-107 357.3 4.0 1.2 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis PNK3P PF08645.11 KKK15013.1 - 1.3e-55 187.5 0.1 1.9e-55 187.0 0.1 1.2 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.6 KKK15013.1 - 1.4e-08 35.0 0.0 4.1e-08 33.5 0.0 1.8 2 0 0 2 2 2 1 AAA domain KTI12 PF08433.10 KKK15013.1 - 0.15 11.4 0.0 0.32 10.4 0.0 1.5 2 0 0 2 2 2 0 Chromatin associated protein KTI12 Med18 PF09637.10 KKK15014.1 - 8.2e-64 215.8 0.0 9.3e-64 215.6 0.0 1.0 1 0 0 1 1 1 1 Med18 protein S36_mt PF10937.8 KKK15015.1 - 3e-38 131.9 0.2 3.5e-38 131.7 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S36, mitochondrial CoA_trans PF01144.23 KKK15016.1 - 1.3e-93 312.3 2.9 1.2e-59 201.3 0.2 2.1 2 0 0 2 2 2 2 Coenzyme A transferase Mal_decarbox_Al PF16957.5 KKK15016.1 - 0.0055 15.1 0.2 0.01 14.2 0.2 1.4 1 0 0 1 1 1 1 Malonate decarboxylase, alpha subunit, transporter AcetylCoA_hyd_C PF13336.6 KKK15016.1 - 0.013 15.4 0.8 0.025 14.5 0.0 1.8 2 0 0 2 2 2 0 Acetyl-CoA hydrolase/transferase C-terminal domain TIP120 PF08623.10 KKK15018.1 - 1.4e-62 210.4 0.1 6.1e-62 208.3 0.0 2.2 2 0 0 2 2 2 1 TATA-binding protein interacting (TIP20) HEAT PF02985.22 KKK15018.1 - 3.3e-11 42.4 8.4 0.076 13.3 0.0 8.7 9 0 0 9 9 9 3 HEAT repeat HEAT_2 PF13646.6 KKK15018.1 - 3.2e-05 24.3 9.0 3.2 8.2 0.0 7.1 5 2 2 7 7 7 2 HEAT repeats Arm PF00514.23 KKK15018.1 - 4e-05 23.5 0.4 2 8.5 0.0 5.1 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 KKK15018.1 - 0.0001 22.7 8.3 1.6 9.4 0.0 7.3 6 1 1 7 7 7 1 HEAT-like repeat TAF6_C PF07571.13 KKK15018.1 - 0.053 13.9 0.1 1.7 9.0 0.0 3.4 2 1 0 3 3 3 0 TAF6 C-terminal HEAT repeat domain ParcG PF10274.9 KKK15018.1 - 0.054 13.6 0.8 39 4.3 0.0 3.6 2 1 1 3 3 3 0 Parkin co-regulated protein Spectrin_like PF18373.1 KKK15018.1 - 0.098 12.7 0.1 0.34 11.0 0.1 1.9 1 0 0 1 1 1 0 Spectrin like domain LRR_4 PF12799.7 KKK15019.1 - 1.7e-24 85.5 44.2 8e-06 26.1 1.5 8.6 7 1 1 8 8 8 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KKK15019.1 - 5.2e-24 83.8 44.8 1.1e-08 34.7 1.2 7.3 4 2 4 8 8 8 7 Leucine rich repeat LRR_1 PF00560.33 KKK15019.1 - 6.8e-06 25.9 26.1 6.9 7.6 0.1 10.4 8 2 0 8 8 8 2 Leucine Rich Repeat LRR_9 PF14580.6 KKK15019.1 - 2.8e-05 23.7 12.6 0.059 12.9 0.0 4.2 1 1 3 4 4 4 4 Leucine-rich repeat LRR_6 PF13516.6 KKK15019.1 - 0.003 17.5 32.1 0.57 10.4 0.0 10.1 11 0 0 11 11 11 4 Leucine Rich repeat zf-ZPR1 PF03367.13 KKK15020.1 - 2.4e-105 349.3 0.1 1.2e-53 181.2 0.0 2.2 2 0 0 2 2 2 2 ZPR1 zinc-finger domain Paired_CXXCH_1 PF09699.10 KKK15020.1 - 0.033 13.9 0.5 3.9 7.3 0.0 2.5 2 0 0 2 2 2 0 Doubled CXXCH motif (Paired_CXXCH_1) Cytochrome_C7 PF14522.6 KKK15020.1 - 0.081 12.9 0.2 0.081 12.9 0.2 2.4 2 1 0 2 2 2 0 Cytochrome c7 and related cytochrome c zinc-ribbons_6 PF07191.12 KKK15020.1 - 0.21 11.6 2.4 3.3 7.8 0.2 2.5 2 0 0 2 2 2 0 zinc-ribbons RTP1_C1 PF10363.9 KKK15021.1 - 2.2e-30 105.1 0.8 9.4e-30 103.1 0.1 2.4 2 0 0 2 2 2 1 Required for nuclear transport of RNA pol II C-terminus 1 RTP1_C2 PF10304.9 KKK15021.1 - 7.2e-09 35.2 0.0 1.8e-08 33.9 0.0 1.8 1 0 0 1 1 1 1 Required for nuclear transport of RNA pol II C-terminus 2 HEAT_EZ PF13513.6 KKK15021.1 - 0.0054 17.2 0.7 1.9 9.1 0.0 3.8 3 0 0 3 3 3 1 HEAT-like repeat M20_dimer PF07687.14 KKK15021.1 - 0.11 12.4 0.0 0.44 10.5 0.0 2.0 1 0 0 1 1 1 0 Peptidase dimerisation domain DBR1 PF05011.13 KKK15022.1 - 6e-47 159.6 2.4 1.1e-45 155.5 0.0 2.5 2 0 0 2 2 2 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.28 KKK15022.1 - 9.5e-08 32.8 0.2 2.1e-07 31.7 0.2 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Rpr2 PF04032.16 KKK15023.1 - 8.9e-11 41.9 0.7 8.9e-11 41.9 0.7 1.7 2 0 0 2 2 2 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain DZR PF12773.7 KKK15023.1 - 0.077 13.0 1.4 0.14 12.2 1.4 1.4 1 0 0 1 1 1 0 Double zinc ribbon LAT PF15234.6 KKK15023.1 - 0.78 9.4 5.8 0.2 11.3 2.1 1.8 2 0 0 2 2 2 0 Linker for activation of T-cells GFA PF04828.14 KKK15023.1 - 0.8 10.1 3.7 0.6 10.5 0.2 2.2 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme ORC6 PF05460.13 KKK15024.1 - 4e-98 329.0 0.1 4.6e-98 328.8 0.1 1.0 1 0 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) Hamartin PF04388.12 KKK15024.1 - 0.25 10.0 7.9 0.35 9.5 7.9 1.2 1 0 0 1 1 1 0 Hamartin protein Pro_isomerase PF00160.21 KKK15025.1 - 5.8e-30 104.7 0.0 4.5e-26 92.0 0.0 2.6 2 1 0 2 2 2 2 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Ferric_reduct PF01794.19 KKK15040.1 - 8.5e-22 77.6 13.0 2e-21 76.4 13.0 1.7 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KKK15040.1 - 7.8e-20 71.0 0.0 1.5e-19 70.0 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 KKK15040.1 - 4.7e-19 69.0 0.0 9.8e-19 68.0 0.0 1.5 2 0 0 2 2 2 1 Ferric reductase NAD binding domain AATase PF07247.12 KKK15041.1 - 2.7e-18 65.8 0.0 4.8e-18 65.0 0.0 1.4 1 1 0 1 1 1 1 Alcohol acetyltransferase Condensation PF00668.20 KKK15041.1 - 0.0051 15.5 0.0 0.031 12.9 0.0 2.2 3 0 0 3 3 3 1 Condensation domain NAC PF01849.18 KKK15042.1 - 6.7e-24 83.6 0.7 1.4e-23 82.6 0.3 1.8 2 0 0 2 2 2 1 NAC domain DUF1564 PF07600.11 KKK15042.1 - 0.044 13.5 0.0 0.16 11.6 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1564) MFS_1 PF07690.16 KKK15045.1 - 2.9e-34 118.5 28.7 2.5e-33 115.5 29.9 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF3218 PF11508.8 KKK15045.1 - 0.16 11.5 0.5 0.28 10.7 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3218) Phage_holin_2_1 PF04971.12 KKK15045.1 - 1.5 8.9 13.1 0.91 9.6 0.7 4.0 3 1 0 3 3 3 0 Bacteriophage P21 holin S Lipase_3 PF01764.25 KKK15046.1 - 3.7e-16 59.3 0.1 1.8e-12 47.3 0.0 2.6 2 0 0 2 2 2 2 Lipase (class 3) Abhydrolase_6 PF12697.7 KKK15046.1 - 0.011 16.4 0.1 0.026 15.2 0.1 1.7 1 0 0 1 1 1 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KKK15046.1 - 0.065 12.5 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 SMC_N PF02463.19 KKK15047.1 - 6.1e-23 81.4 0.0 1.5e-22 80.2 0.0 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KKK15047.1 - 5.6e-13 49.8 12.2 5.6e-13 49.8 12.2 5.4 2 2 1 3 3 2 1 AAA domain AAA_21 PF13304.6 KKK15047.1 - 9e-06 25.7 4.5 0.035 13.9 0.1 3.1 3 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_13 PF13166.6 KKK15047.1 - 0.00048 18.9 68.4 0.0075 15.0 17.8 5.0 4 1 1 5 5 5 4 AAA domain AAA_29 PF13555.6 KKK15047.1 - 0.0036 17.0 0.0 0.0072 16.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.27 KKK15047.1 - 0.078 13.5 0.0 0.078 13.5 0.0 4.3 3 1 0 3 3 2 0 ABC transporter AAA_25 PF13481.6 KKK15047.1 - 0.13 11.8 4.2 0.3 10.6 0.0 3.3 3 0 0 3 3 3 0 AAA domain PSP1 PF04468.12 KKK15047.1 - 0.38 11.1 0.1 0.38 11.1 0.1 3.6 3 0 0 3 3 3 0 PSP1 C-terminal conserved region AAA PF00004.29 KKK15047.1 - 1 9.8 6.5 1.1 9.6 0.0 3.5 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Tropomyosin_1 PF12718.7 KKK15047.1 - 3.2 7.9 88.6 0.06 13.5 17.4 6.6 2 2 2 5 5 5 0 Tropomyosin like SMBP PF16785.5 KKK15047.1 - 7.4 6.8 13.5 1.4 9.2 1.3 3.6 3 0 0 3 3 3 0 Small metal-binding protein FMN_dh PF01070.18 KKK15048.1 - 1.2e-105 353.4 0.0 1.3e-105 353.2 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase NMO PF03060.15 KKK15048.1 - 3.8e-05 23.2 0.2 5.2e-05 22.8 0.2 1.1 1 0 0 1 1 1 1 Nitronate monooxygenase ThiG PF05690.14 KKK15048.1 - 0.0014 18.0 0.1 0.31 10.3 0.1 2.5 3 0 0 3 3 3 2 Thiazole biosynthesis protein ThiG Glu_synthase PF01645.17 KKK15048.1 - 0.034 13.3 0.1 0.034 13.3 0.1 1.6 2 0 0 2 2 2 0 Conserved region in glutamate synthase IMPDH PF00478.25 KKK15048.1 - 0.052 12.6 0.4 0.073 12.1 0.4 1.3 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain Rab_eff_C PF04698.12 KKK15049.1 - 0.014 13.8 0.2 0.016 13.6 0.2 1.0 1 0 0 1 1 1 0 Rab effector MyRIP/melanophilin C-terminus Ntox28 PF15605.6 KKK15049.1 - 0.029 14.6 0.7 0.037 14.3 0.7 1.2 1 0 0 1 1 1 0 Bacterial toxin 28 Osmo_CC PF08946.10 KKK15049.1 - 0.039 14.2 3.7 0.95 9.8 0.1 2.4 1 1 1 2 2 2 0 Osmosensory transporter coiled coil Ctr PF04145.15 KKK15050.1 - 3.1e-32 112.2 0.2 3.8e-32 112.0 0.2 1.1 1 0 0 1 1 1 1 Ctr copper transporter family PAP2 PF01569.21 KKK15050.1 - 5.6 6.7 8.1 21 4.9 8.1 1.9 1 1 0 1 1 1 0 PAP2 superfamily Abhydrolase_2 PF02230.16 KKK15051.1 - 1.7e-61 207.8 0.0 2.1e-61 207.5 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 KKK15051.1 - 3.7e-08 32.9 0.2 1.9e-05 24.0 0.0 2.9 2 1 1 3 3 3 1 Serine aminopeptidase, S33 FSH1 PF03959.13 KKK15051.1 - 1.4e-06 28.1 0.0 4.9e-06 26.3 0.0 1.8 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 KKK15051.1 - 0.00017 22.2 0.0 0.054 14.1 0.0 2.1 1 1 1 2 2 2 2 Alpha/beta hydrolase family DLH PF01738.18 KKK15051.1 - 0.00021 20.9 0.0 0.0003 20.4 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 KKK15051.1 - 0.00026 20.5 0.0 0.016 14.7 0.0 2.3 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 KKK15051.1 - 0.0003 20.7 0.0 0.0007 19.5 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold LIP PF03583.14 KKK15051.1 - 0.017 14.5 0.1 0.27 10.5 0.0 2.1 2 0 0 2 2 2 0 Secretory lipase Abhydrolase_1 PF00561.20 KKK15051.1 - 0.04 13.6 0.9 8.8 5.9 0.9 2.8 1 1 1 2 2 2 0 alpha/beta hydrolase fold Lipase_3 PF01764.25 KKK15051.1 - 0.087 12.7 0.0 0.16 11.8 0.0 1.5 1 1 0 1 1 1 0 Lipase (class 3) Abhydro_lipase PF04083.16 KKK15051.1 - 0.14 11.8 0.0 0.69 9.5 0.0 1.9 2 0 0 2 2 2 0 Partial alpha/beta-hydrolase lipase region FSH1 PF03959.13 KKK15052.1 - 1.5e-35 122.8 0.0 1.8e-35 122.5 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 KKK15052.1 - 0.00014 22.6 0.1 0.00018 22.2 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 KKK15052.1 - 0.063 13.1 0.3 0.15 11.8 0.3 1.6 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase FPN1 PF06963.12 KKK15059.1 - 1.2e-144 482.1 17.8 1.4e-144 481.9 17.8 1.0 1 0 0 1 1 1 1 Ferroportin1 (FPN1) HAD_2 PF13419.6 KKK15060.1 - 2.5e-20 73.3 0.0 3.6e-20 72.8 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KKK15060.1 - 2.7e-07 31.1 0.2 1.8e-06 28.4 0.2 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KKK15060.1 - 0.0018 18.3 0.0 0.0029 17.6 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 KKK15060.1 - 0.014 15.8 0.0 0.021 15.2 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Rit1_C PF17184.4 KKK15061.1 - 3.7e-103 344.7 0.0 4.7e-103 344.4 0.0 1.1 1 0 0 1 1 1 1 Rit1 N-terminal domain Init_tRNA_PT PF04179.12 KKK15061.1 - 2.8e-33 114.5 0.0 6.5e-33 113.3 0.0 1.7 1 0 0 1 1 1 1 Rit1 DUSP-like domain Ribosomal_S16 PF00886.19 KKK15062.1 - 4.1e-24 84.4 0.1 5.7e-24 83.9 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S16 YjeF_N PF03853.15 KKK15063.1 - 3.1e-24 85.8 0.0 6e-24 84.8 0.0 1.4 1 1 1 2 2 2 1 YjeF-related protein N-terminus RRM_1 PF00076.22 KKK15064.1 - 5.3e-17 61.4 0.0 3.3e-13 49.3 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KKK15064.1 - 0.005 16.7 0.0 0.0094 15.8 0.0 1.4 1 0 0 1 1 1 1 Occluded RNA-recognition motif CH PF00307.31 KKK15065.1 - 6.5e-44 148.6 0.5 7.6e-22 77.6 0.0 2.6 2 0 0 2 2 2 2 Calponin homology (CH) domain EFhand_Ca_insen PF08726.10 KKK15065.1 - 1.4e-28 98.7 0.1 4.4e-28 97.2 0.1 1.9 1 0 0 1 1 1 1 Ca2+ insensitive EF hand RRM_1 PF00076.22 KKK15065.1 - 1.2e-17 63.5 0.0 2.8e-17 62.3 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CAMSAP_CH PF11971.8 KKK15065.1 - 2.3e-08 33.7 0.1 8.7e-07 28.7 0.0 2.7 2 0 0 2 2 2 1 CAMSAP CH domain FoP_duplication PF13865.6 KKK15065.1 - 2.2e-07 31.3 7.7 2.2e-07 31.3 7.7 3.4 4 0 0 4 4 4 1 C-terminal duplication domain of Friend of PRMT1 EF-hand_6 PF13405.6 KKK15065.1 - 0.00043 20.0 0.0 0.0024 17.7 0.0 2.4 1 0 0 1 1 1 1 EF-hand domain EF-hand_1 PF00036.32 KKK15065.1 - 0.0052 16.2 0.1 0.056 13.0 0.0 2.6 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 KKK15065.1 - 0.014 15.2 0.0 0.061 13.2 0.0 2.2 2 0 0 2 2 2 0 EF-hand domain pair Aldo_ket_red PF00248.21 KKK15066.1 - 5.5e-37 127.6 0.0 1.2e-34 119.8 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family PUL PF08324.11 KKK15067.1 - 2.4e-73 246.8 0.7 3.7e-73 246.2 0.7 1.3 1 0 0 1 1 1 1 PUL domain PFU PF09070.11 KKK15067.1 - 1.4e-44 151.0 0.1 3e-44 149.9 0.1 1.6 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.32 KKK15067.1 - 8.3e-30 102.4 12.4 2.4e-07 31.3 0.0 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat BBS2_Mid PF14783.6 KKK15067.1 - 0.014 15.4 0.0 0.97 9.5 0.0 3.0 2 1 1 3 3 3 0 Ciliary BBSome complex subunit 2, middle region WD40 PF00400.32 KKK15068.1 - 1.6e-22 79.4 9.0 3.2e-07 30.9 0.0 6.5 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKK15068.1 - 1e-07 32.1 0.3 0.24 11.7 0.0 4.0 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KKK15068.1 - 0.0037 16.3 0.1 0.23 10.4 0.0 2.5 2 0 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Me-amine-dh_H PF06433.11 KKK15068.1 - 0.0075 15.2 0.0 0.52 9.1 0.0 2.1 2 0 0 2 2 2 2 Methylamine dehydrogenase heavy chain (MADH) Nup160 PF11715.8 KKK15068.1 - 0.012 14.3 1.0 1 7.9 0.1 2.5 1 1 1 2 2 2 0 Nucleoporin Nup120/160 dsrm PF00035.26 KKK15068.1 - 0.15 12.8 0.0 0.39 11.5 0.0 1.7 1 0 0 1 1 1 0 Double-stranded RNA binding motif MutS_V PF00488.21 KKK15074.1 - 1e-72 244.1 0.4 2.9e-72 242.7 0.1 2.0 2 0 0 2 2 2 1 MutS domain V MutS_III PF05192.18 KKK15074.1 - 2.4e-37 129.0 0.7 5.3e-37 127.9 0.7 1.6 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 KKK15074.1 - 6.8e-13 48.8 0.0 2.5e-12 47.1 0.0 2.0 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 KKK15074.1 - 2.3e-10 40.9 0.0 8.6e-10 39.0 0.0 2.1 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.18 KKK15074.1 - 0.00033 20.9 0.1 0.00096 19.4 0.1 1.8 1 0 0 1 1 1 1 MutS family domain IV DUF4911 PF16256.5 KKK15074.1 - 0.0074 16.2 0.2 0.029 14.3 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4911) p450 PF00067.22 KKK15075.1 - 1.6e-68 231.6 0.0 1.8e-68 231.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 L31 PF09784.9 KKK15076.1 - 2.4e-45 153.1 1.1 2.6e-45 153.0 1.1 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 PI3K_C2 PF00792.24 KKK15076.1 - 0.13 12.1 0.0 0.19 11.7 0.0 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase C2 Acyltransferase PF01553.21 KKK15077.1 - 1.2e-14 54.0 0.0 2.2e-14 53.2 0.0 1.4 1 1 0 1 1 1 1 Acyltransferase DEAD PF00270.29 KKK15080.1 - 1.4e-39 135.6 0.1 2.7e-39 134.8 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KKK15080.1 - 1.1e-29 103.0 0.1 3.8e-29 101.3 0.1 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KKK15080.1 - 0.0021 18.1 0.0 0.01 15.9 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit TERB2 PF15101.6 KKK15080.1 - 0.12 12.4 0.3 0.28 11.2 0.3 1.5 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Lin-8 PF03353.15 KKK15081.1 - 0.63 9.6 5.4 0.83 9.2 5.4 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Kelch_4 PF13418.6 KKK15083.1 - 1.4e-05 25.0 1.1 0.15 12.1 0.1 4.1 3 1 0 3 3 3 3 Galactose oxidase, central domain Kelch_5 PF13854.6 KKK15083.1 - 0.017 15.1 0.1 0.12 12.4 0.0 2.4 2 0 0 2 2 2 0 Kelch motif MIOX PF05153.15 KKK15084.1 - 1.2e-115 385.4 0.5 1.4e-115 385.1 0.5 1.1 1 0 0 1 1 1 1 Myo-inositol oxygenase HD PF01966.22 KKK15084.1 - 0.03 14.5 0.1 1.9 8.8 0.0 2.5 2 0 0 2 2 2 0 HD domain Speriolin_C PF15059.6 KKK15084.1 - 0.12 12.5 0.4 0.2 11.8 0.4 1.3 1 0 0 1 1 1 0 Speriolin C-terminus CP12 PF02672.15 KKK15084.1 - 0.17 12.7 1.8 0.2 12.4 0.3 1.9 2 0 0 2 2 2 0 CP12 domain Glyco_hydro_76 PF03663.14 KKK15092.1 - 8.2e-140 466.5 21.5 9.7e-140 466.2 21.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 KKK15092.1 - 0.059 12.4 12.5 0.25 10.4 2.1 2.9 1 1 1 3 3 3 0 Glycosyl Hydrolase Family 88 LOR PF04525.12 KKK15093.1 - 3.2e-07 30.1 0.0 1.6e-06 27.8 0.0 2.0 1 1 0 1 1 1 1 LURP-one-related APH PF01636.23 KKK15094.1 - 0.0017 18.4 0.0 0.0024 17.8 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family ADH_N PF08240.12 KKK15095.1 - 7e-22 77.4 0.1 1.3e-21 76.5 0.1 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KKK15095.1 - 1.2e-17 64.1 0.0 2e-17 63.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KKK15095.1 - 0.0054 17.8 0.0 0.0094 17.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase zf-PARP PF00645.18 KKK15096.1 - 0.015 16.1 0.0 0.033 15.0 0.0 1.5 1 0 0 1 1 1 0 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region AAA_2 PF07724.14 KKK15097.1 - 3.4e-46 157.5 0.0 3.6e-44 150.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 KKK15097.1 - 5.8e-35 119.3 1.0 5.8e-35 119.3 1.0 2.6 1 1 1 2 2 2 1 AAA lid domain ClpB_D2-small PF10431.9 KKK15097.1 - 5.3e-27 93.7 0.2 1.8e-26 92.0 0.2 2.0 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 KKK15097.1 - 4.6e-19 69.2 0.0 3.2e-10 40.5 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KKK15097.1 - 3.2e-13 49.9 1.2 2.2e-08 34.2 0.0 3.4 4 1 0 4 4 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KKK15097.1 - 3.7e-09 37.2 8.7 0.00013 22.3 0.2 4.4 3 2 1 4 4 4 2 AAA ATPase domain Sigma54_activat PF00158.26 KKK15097.1 - 1.4e-08 34.6 0.4 9.3e-05 22.2 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_22 PF13401.6 KKK15097.1 - 3.8e-08 33.7 2.4 0.0074 16.6 0.0 3.7 3 2 0 3 3 3 2 AAA domain TniB PF05621.11 KKK15097.1 - 7.3e-06 25.5 0.0 0.012 15.0 0.0 3.6 3 1 0 3 3 2 1 Bacterial TniB protein AAA_7 PF12775.7 KKK15097.1 - 1.4e-05 24.7 0.0 0.031 13.8 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region ATPase_2 PF01637.18 KKK15097.1 - 1.7e-05 24.9 4.2 2.4 8.0 0.0 4.3 3 2 1 4 4 4 2 ATPase domain predominantly from Archaea AAA_14 PF13173.6 KKK15097.1 - 1.7e-05 24.9 0.0 0.23 11.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 KKK15097.1 - 1.8e-05 24.7 0.0 0.094 12.6 0.0 2.5 2 0 0 2 2 2 2 NACHT domain AAA_28 PF13521.6 KKK15097.1 - 0.00012 22.4 2.0 0.056 13.7 0.0 3.7 3 1 0 3 3 3 1 AAA domain IstB_IS21 PF01695.17 KKK15097.1 - 0.00015 21.6 0.0 0.77 9.5 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_18 PF13238.6 KKK15097.1 - 0.00015 22.3 0.8 0.66 10.5 0.0 3.3 3 0 0 3 3 2 2 AAA domain SRP54 PF00448.22 KKK15097.1 - 0.00032 20.4 0.1 0.059 13.0 0.0 2.5 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_24 PF13479.6 KKK15097.1 - 0.00034 20.4 0.0 0.33 10.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KKK15097.1 - 0.00093 19.0 1.3 0.095 12.4 0.0 3.6 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.22 KKK15097.1 - 0.00095 19.5 0.0 0.74 10.2 0.0 2.8 2 1 0 2 2 2 1 RNA helicase AAA_19 PF13245.6 KKK15097.1 - 0.0013 19.1 0.5 0.14 12.5 0.1 3.2 2 1 0 2 2 2 1 AAA domain ResIII PF04851.15 KKK15097.1 - 0.0018 18.3 0.0 4.6 7.2 0.0 3.2 3 0 0 3 3 2 0 Type III restriction enzyme, res subunit Mg_chelatase PF01078.21 KKK15097.1 - 0.0024 17.3 0.1 2.5 7.4 0.1 3.1 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI TsaE PF02367.17 KKK15097.1 - 0.0027 17.7 0.1 2.4 8.2 0.0 2.7 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 KKK15097.1 - 0.0031 18.0 1.1 2 8.9 0.0 3.3 3 0 0 3 3 3 1 ABC transporter TrwB_AAD_bind PF10412.9 KKK15097.1 - 0.0046 15.9 0.1 0.27 10.1 0.1 2.4 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain Zeta_toxin PF06414.12 KKK15097.1 - 0.0047 16.2 0.0 0.66 9.2 0.0 2.7 2 0 0 2 2 2 1 Zeta toxin Roc PF08477.13 KKK15097.1 - 0.0055 16.9 0.0 0.71 10.1 0.0 2.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase DUF853 PF05872.12 KKK15097.1 - 0.0081 14.8 0.1 0.072 11.7 0.1 2.3 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF853) DUF815 PF05673.13 KKK15097.1 - 0.0093 15.2 0.1 0.48 9.5 0.1 2.9 2 1 0 2 2 2 1 Protein of unknown function (DUF815) RsgA_GTPase PF03193.16 KKK15097.1 - 0.0099 15.8 0.7 2.3 8.1 0.0 2.7 3 0 0 3 3 2 1 RsgA GTPase ATP_bind_1 PF03029.17 KKK15097.1 - 0.013 15.3 0.1 0.24 11.2 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein PduV-EutP PF10662.9 KKK15097.1 - 0.013 15.3 0.0 0.55 10.0 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NTPase_1 PF03266.15 KKK15097.1 - 0.03 14.2 0.1 0.39 10.6 0.0 2.5 2 0 0 2 2 2 0 NTPase RuvB_N PF05496.12 KKK15097.1 - 0.039 13.7 0.2 9.3 6.0 0.0 3.8 4 0 0 4 4 4 0 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 KKK15097.1 - 0.046 13.9 3.0 5.3 7.2 0.0 3.0 3 0 0 3 3 2 0 AAA domain AAA_21 PF13304.6 KKK15097.1 - 0.059 13.2 1.0 0.87 9.3 0.0 3.0 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 KKK15097.1 - 0.078 12.6 0.1 1.5 8.3 0.0 2.8 2 0 0 2 2 2 0 AAA domain DNA_pol3_delta2 PF13177.6 KKK15097.1 - 0.08 12.7 0.1 5.1 6.9 0.0 2.7 2 0 0 2 2 2 0 DNA polymerase III, delta subunit AAA_6 PF12774.7 KKK15097.1 - 0.096 11.6 0.1 2.7 6.9 0.0 2.3 2 0 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region UvrD-helicase PF00580.21 KKK15097.1 - 0.12 11.9 5.2 0.32 10.5 0.1 2.2 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain AAA_23 PF13476.6 KKK15097.1 - 0.21 12.0 11.8 2.8 8.4 5.6 3.7 4 0 0 4 4 3 0 AAA domain Zw10 PF06248.13 KKK15097.1 - 0.45 9.0 3.1 0.73 8.3 3.1 1.2 1 0 0 1 1 1 0 Centromere/kinetochore Zw10 GAS PF13851.6 KKK15097.1 - 0.71 9.2 12.8 1.5 8.1 12.8 1.5 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DivIC PF04977.15 KKK15097.1 - 1.1 9.1 14.2 1.3 8.8 10.1 2.5 1 1 1 2 2 2 0 Septum formation initiator UPF0242 PF06785.11 KKK15097.1 - 2.4 8.2 12.2 5.6 7.0 12.2 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Prefoldin_2 PF01920.20 KKK15097.1 - 4 7.4 13.1 4.4 7.3 3.7 2.9 1 1 1 2 2 2 0 Prefoldin subunit GrpE PF01025.19 KKK15097.1 - 4.3 7.0 12.3 11 5.7 12.3 1.7 1 0 0 1 1 1 0 GrpE DUF4407 PF14362.6 KKK15097.1 - 6.3 6.1 10.4 11 5.2 10.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) MutS_V PF00488.21 KKK15098.1 - 2e-26 93.2 0.2 5.5e-26 91.8 0.1 1.7 2 0 0 2 2 2 1 MutS domain V MutS_III PF05192.18 KKK15098.1 - 2.9e-17 63.5 0.1 8.1e-17 62.1 0.0 1.7 2 0 0 2 2 2 1 MutS domain III MutS_IV PF05190.18 KKK15098.1 - 0.0077 16.6 0.0 0.031 14.6 0.0 2.1 2 0 0 2 2 2 1 MutS family domain IV MMgT PF10270.9 KKK15099.1 - 7.9e-25 87.1 0.3 9.4e-25 86.9 0.3 1.0 1 0 0 1 1 1 1 Membrane magnesium transporter EF1_GNE PF00736.19 KKK15100.1 - 3.6e-31 107.2 3.0 5.8e-31 106.5 3.0 1.3 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.9 KKK15100.1 - 1.6e-11 44.4 4.5 1.6e-11 44.4 4.5 2.5 3 0 0 3 3 3 1 Eukaryotic elongation factor 1 beta central acidic region GST_C_3 PF14497.6 KKK15100.1 - 0.00087 19.4 0.4 0.0018 18.4 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KKK15100.1 - 0.0038 17.4 1.5 0.0077 16.4 0.1 2.3 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KKK15100.1 - 0.019 15.0 0.2 0.53 10.3 0.2 2.5 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain UQ_con PF00179.26 KKK15101.1 - 3.1e-36 124.1 0.0 4.8e-36 123.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KKK15101.1 - 0.019 14.7 0.0 0.037 13.7 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic E2 family B Sas10 PF09368.10 KKK15102.1 - 6.5e-30 103.4 8.0 6.5e-30 103.4 8.0 3.4 3 0 0 3 3 3 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.15 KKK15102.1 - 8.7e-13 48.7 1.3 5.4e-12 46.2 0.0 2.9 2 0 0 2 2 2 1 Sas10/Utp3/C1D family DUF778 PF05608.12 KKK15102.1 - 0.17 12.3 1.6 0.5 10.7 0.9 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF778) adh_short PF00106.25 KKK15103.1 - 8.5e-16 58.0 0.0 1e-15 57.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KKK15103.1 - 1.9e-10 40.7 0.0 2.6e-10 40.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KKK15103.1 - 2.7e-08 33.9 0.2 4.9e-08 33.1 0.2 1.4 1 1 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 KKK15103.1 - 8.9e-05 22.0 0.0 0.00012 21.6 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_7 PF13241.6 KKK15103.1 - 0.001 19.5 0.2 0.0016 18.9 0.2 1.2 1 0 0 1 1 1 1 Putative NAD(P)-binding THF_DHG_CYH_C PF02882.19 KKK15103.1 - 0.0022 17.4 0.2 0.0035 16.7 0.2 1.2 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.21 KKK15103.1 - 0.014 14.9 0.0 0.017 14.6 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KKK15103.1 - 0.016 14.3 0.0 0.021 14.0 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Shikimate_DH PF01488.20 KKK15103.1 - 0.019 15.0 0.2 0.028 14.5 0.2 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 KKK15103.1 - 0.028 14.3 0.3 0.042 13.7 0.3 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 KKK15103.1 - 0.034 14.4 0.1 0.063 13.5 0.0 1.4 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain PTS_2-RNA PF01885.16 KKK15103.1 - 0.059 13.4 0.0 0.074 13.1 0.0 1.1 1 0 0 1 1 1 0 RNA 2'-phosphotransferase, Tpt1 / KptA family 2-Hacid_dh_C PF02826.19 KKK15103.1 - 0.076 12.4 0.1 0.11 11.9 0.1 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_10 PF13460.6 KKK15103.1 - 0.084 12.8 0.1 0.13 12.1 0.1 1.5 1 1 0 1 1 1 0 NAD(P)H-binding ApbA PF02558.16 KKK15103.1 - 0.089 12.4 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA FTCD_C PF04961.12 KKK15103.1 - 0.092 12.5 0.1 0.12 12.1 0.1 1.2 1 0 0 1 1 1 0 Formiminotransferase-cyclodeaminase FA_hydroxylase PF04116.13 KKK15104.1 - 1e-17 64.7 5.8 1e-17 64.7 5.8 2.2 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily Spt5_N PF11942.8 KKK15104.1 - 1.9 9.5 7.1 3.5 8.7 7.1 1.3 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal Pribosyltran PF00156.27 KKK15105.1 - 1.4e-05 24.7 0.0 2.3e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain SLAC1 PF03595.17 KKK15106.1 - 6.3e-76 255.7 51.6 7.3e-76 255.5 51.6 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel COX14 PF14880.6 KKK15106.1 - 0.053 13.4 0.2 0.053 13.4 0.2 2.3 2 0 0 2 2 2 0 Cytochrome oxidase c assembly BRCT_2 PF16589.5 KKK15107.1 - 1.4e-05 25.4 0.0 1.9e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 KKK15107.1 - 0.00011 22.5 0.2 0.00018 21.8 0.2 1.3 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 KKK15107.1 - 0.00014 21.7 0.2 0.00024 21.0 0.2 1.4 1 1 0 1 1 1 1 twin BRCT domain BRCT_3 PF18428.1 KKK15107.1 - 0.057 13.5 0.1 0.081 13.0 0.1 1.4 1 1 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain Nup188_C PF18378.1 KKK15108.1 - 2.6e-147 490.5 0.1 5e-147 489.6 0.1 1.5 1 0 0 1 1 1 1 Nuclear pore protein NUP188 C-terminal domain Nup188 PF10487.9 KKK15108.1 - 8.5e-83 278.8 0.0 2.4e-82 277.3 0.0 1.7 1 1 0 1 1 1 1 Nucleoporin subcomplex protein binding to Pom34 T2SSF PF00482.23 KKK15108.1 - 0.093 12.7 0.1 0.24 11.4 0.1 1.7 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F IGPS PF00218.21 KKK15109.1 - 4e-98 327.6 0.0 9.7e-98 326.4 0.0 1.6 2 0 0 2 2 2 1 Indole-3-glycerol phosphate synthase PRAI PF00697.22 KKK15109.1 - 9.7e-56 188.6 0.0 7.6e-54 182.5 0.0 2.7 2 1 1 3 3 3 2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase GATase PF00117.28 KKK15109.1 - 4.7e-49 166.7 0.0 7.8e-49 166.0 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I QRPTase_C PF01729.19 KKK15109.1 - 0.00051 19.9 0.1 0.0055 16.5 0.0 2.7 3 0 0 3 3 3 1 Quinolinate phosphoribosyl transferase, C-terminal domain Peptidase_C26 PF07722.13 KKK15109.1 - 0.0014 18.4 1.3 0.012 15.4 1.3 2.1 1 1 0 1 1 1 1 Peptidase C26 His_biosynth PF00977.21 KKK15109.1 - 0.014 14.9 0.2 0.048 13.1 0.0 1.9 2 0 0 2 2 2 0 Histidine biosynthesis protein NanE PF04131.14 KKK15109.1 - 0.021 14.0 0.4 0.086 12.0 0.0 2.2 3 0 0 3 3 3 0 Putative N-acetylmannosamine-6-phosphate epimerase AMP-binding PF00501.28 KKK15110.1 - 4.8e-76 256.1 0.1 2.6e-75 253.6 0.1 1.9 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KKK15110.1 - 1.7e-15 57.7 0.2 4.2e-15 56.5 0.0 1.8 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Use1 PF09753.9 KKK15112.1 - 8.7e-10 38.7 6.1 3.9e-09 36.6 6.1 2.1 1 1 0 1 1 1 1 Membrane fusion protein Use1 GldM_N PF12081.8 KKK15112.1 - 0.1 12.7 1.0 0.19 11.8 0.0 1.8 2 0 0 2 2 2 0 GldM N-terminal domain XRCC4 PF06632.12 KKK15112.1 - 0.21 10.4 6.9 0.42 9.4 6.9 1.5 1 1 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 Pes-10 PF07149.11 KKK15112.1 - 0.77 8.7 6.0 1.2 8.1 6.0 1.2 1 0 0 1 1 1 0 Pes-10 DUF1664 PF07889.12 KKK15112.1 - 2 8.5 4.1 12 5.9 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Fzo_mitofusin PF04799.13 KKK15112.1 - 5.1 6.6 5.6 7.4 6.1 1.6 2.3 2 0 0 2 2 2 0 fzo-like conserved region G-alpha PF00503.20 KKK15113.1 - 1.4e-124 415.9 0.9 1.6e-124 415.7 0.9 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KKK15113.1 - 2.3e-15 56.5 1.6 2.4e-10 40.1 0.1 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family zf-CHC2 PF01807.20 KKK15113.1 - 6.9e-05 22.6 0.0 0.00033 20.4 0.0 2.0 2 0 0 2 2 2 1 CHC2 zinc finger Gtr1_RagA PF04670.12 KKK15113.1 - 0.0028 17.1 3.1 0.086 12.2 0.1 2.5 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region AAA_29 PF13555.6 KKK15113.1 - 0.013 15.2 0.0 0.034 13.9 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Roc PF08477.13 KKK15113.1 - 0.017 15.3 0.7 2.4 8.4 0.0 2.9 2 1 1 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase MCM PF00493.23 KKK15113.1 - 0.055 12.6 0.1 0.12 11.5 0.1 1.5 1 1 0 1 1 1 0 MCM P-loop domain AAA_23 PF13476.6 KKK15113.1 - 0.06 13.8 0.1 0.13 12.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain GTP_EFTU PF00009.27 KKK15113.1 - 0.084 12.4 0.0 1.2 8.7 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain FtsK_SpoIIIE PF01580.18 KKK15113.1 - 0.13 11.6 0.0 0.28 10.5 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family MMR_HSR1 PF01926.23 KKK15113.1 - 0.13 12.3 0.1 8.4 6.5 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase UCH PF00443.29 KKK15120.1 - 7.5e-35 120.7 0.0 1.1e-30 107.0 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KKK15120.1 - 7.4e-08 32.4 3.1 1.6e-06 27.9 3.1 2.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase AlaDh_PNT_N PF05222.15 KKK15121.1 - 2.6e-30 105.5 0.0 4.1e-30 104.9 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.21 KKK15121.1 - 1.4e-05 24.5 0.1 0.00018 20.9 0.1 2.4 1 1 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ThiC-associated PF13667.6 KKK15121.1 - 0.11 12.4 0.1 0.21 11.5 0.1 1.4 1 0 0 1 1 1 0 ThiC-associated domain Complex1_51K PF01512.17 KKK15128.1 - 2.1e-45 154.3 0.0 3.5e-45 153.6 0.0 1.4 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 KKK15128.1 - 1.9e-28 98.4 0.3 4.6e-28 97.1 0.3 1.7 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.9 KKK15128.1 - 3.3e-08 33.3 0.0 9.5e-08 31.8 0.0 1.9 1 0 0 1 1 1 1 SLBB domain SET PF00856.28 KKK15128.1 - 0.00011 22.6 0.0 0.00022 21.6 0.0 1.5 1 0 0 1 1 1 1 SET domain SAPS PF04499.15 KKK15129.1 - 6.4e-80 269.3 0.2 4.5e-79 266.5 0.0 1.9 2 0 0 2 2 2 1 SIT4 phosphatase-associated protein Mito_fiss_reg PF05308.11 KKK15129.1 - 0.26 11.4 3.4 0.6 10.1 3.4 1.6 1 0 0 1 1 1 0 Mitochondrial fission regulator SAPS PF04499.15 KKK15130.1 - 2.7e-122 409.1 1.2 1.1e-120 403.7 0.0 2.4 2 1 1 3 3 3 1 SIT4 phosphatase-associated protein FAM176 PF14851.6 KKK15130.1 - 0.22 11.2 1.3 0.53 9.9 1.3 1.5 1 0 0 1 1 1 0 FAM176 family Afi1 PF07792.12 KKK15132.1 - 1.3e-45 155.1 1.1 2.3e-45 154.3 1.1 1.4 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking SPA PF08616.10 KKK15132.1 - 2.2e-37 127.5 0.0 3.7e-37 126.8 0.0 1.4 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.9 KKK15132.1 - 2.1e-08 33.3 0.2 0.0098 14.6 0.0 3.6 3 1 1 4 4 4 3 Transport protein Avl9 DUF2347 PF09804.9 KKK15132.1 - 0.036 13.6 0.0 0.11 12.0 0.0 1.8 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) Dynactin PF12455.8 KKK15134.1 - 0.025 13.8 0.2 0.04 13.2 0.2 1.3 1 0 0 1 1 1 0 Dynein associated protein Hep_59 PF07052.11 KKK15135.1 - 1.6e-17 64.2 0.0 1.6e-17 64.2 0.0 3.6 3 2 0 3 3 3 1 Hepatocellular carcinoma-associated antigen 59 RNB PF00773.19 KKK15136.1 - 7.7e-50 170.1 0.0 3.6e-37 128.4 0.0 2.3 2 0 0 2 2 2 2 RNB domain MARVEL PF01284.23 KKK15137.1 - 0.00079 19.5 13.8 0.0024 17.9 14.0 1.6 1 1 0 1 1 1 1 Membrane-associating domain Kinocilin PF15033.6 KKK15137.1 - 0.35 10.5 2.9 0.31 10.7 1.7 1.5 1 1 0 1 1 1 0 Kinocilin protein FAD_binding_4 PF01565.23 KKK15138.1 - 6.7e-20 71.2 0.7 1.1e-19 70.6 0.4 1.5 2 0 0 2 2 2 1 FAD binding domain Cys_Met_Meta_PP PF01053.20 KKK15139.1 - 1.5e-63 214.6 0.0 3.5e-63 213.4 0.0 1.5 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 KKK15139.1 - 0.0015 17.6 0.0 0.0043 16.1 0.0 1.7 2 0 0 2 2 2 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 KKK15139.1 - 0.02 14.1 0.0 0.034 13.3 0.0 1.4 1 1 0 1 1 1 0 Aminotransferase class I and II GRAB PF10375.9 KKK15143.1 - 1.3e-08 34.4 0.1 2.6e-08 33.4 0.1 1.6 1 0 0 1 1 1 1 GRIP-related Arf-binding domain Filament PF00038.21 KKK15143.1 - 2.9e-05 23.8 48.8 0.0066 16.1 17.0 3.2 1 1 2 3 3 3 3 Intermediate filament protein Phage_GP20 PF06810.11 KKK15143.1 - 0.00053 19.8 4.1 0.00053 19.8 4.1 5.0 2 1 2 5 5 5 2 Phage minor structural protein GP20 DUF4407 PF14362.6 KKK15143.1 - 0.0025 17.2 40.9 0.025 14.0 5.7 3.2 1 1 2 3 3 3 2 Domain of unknown function (DUF4407) Tup_N PF08581.10 KKK15143.1 - 0.0026 18.0 2.6 0.0026 18.0 2.6 5.0 3 3 1 4 4 4 2 Tup N-terminal RPW8 PF05659.11 KKK15143.1 - 0.0027 17.4 1.8 0.0027 17.4 1.8 3.7 1 1 1 3 3 3 1 Arabidopsis broad-spectrum mildew resistance protein RPW8 DUF3584 PF12128.8 KKK15143.1 - 0.012 13.2 44.5 0.019 12.5 44.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Golgin_A5 PF09787.9 KKK15143.1 - 0.027 14.0 55.6 0.45 9.9 19.2 3.4 1 1 2 3 3 3 0 Golgin subfamily A member 5 XhlA PF10779.9 KKK15143.1 - 0.043 14.0 25.3 0.1 12.8 1.7 4.7 3 1 1 4 4 4 0 Haemolysin XhlA Spc7 PF08317.11 KKK15143.1 - 0.068 12.0 51.7 0.7 8.7 26.8 2.6 1 1 1 2 2 2 0 Spc7 kinetochore protein FAM184 PF15665.5 KKK15143.1 - 0.077 12.8 53.9 0.3 10.8 16.8 3.2 1 1 2 3 3 3 0 Family with sequence similarity 184, A and B Atg14 PF10186.9 KKK15143.1 - 0.29 10.2 43.8 0.22 10.6 22.9 2.4 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 IFT57 PF10498.9 KKK15143.1 - 0.32 9.9 41.7 0.13 11.2 14.5 3.2 1 1 2 3 3 3 0 Intra-flagellar transport protein 57 BST2 PF16716.5 KKK15143.1 - 0.35 11.5 44.3 0.12 13.0 9.0 5.7 1 1 3 5 5 5 0 Bone marrow stromal antigen 2 DUF1664 PF07889.12 KKK15143.1 - 0.36 10.9 29.0 0.67 10.0 3.6 3.9 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) FPP PF05911.11 KKK15143.1 - 1.4 7.0 55.8 0.026 12.7 22.3 2.5 2 1 1 3 3 3 0 Filament-like plant protein, long coiled-coil HMMR_N PF15905.5 KKK15143.1 - 1.6 8.1 54.9 2.6 7.5 23.2 2.8 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal DUF4250 PF14056.6 KKK15143.1 - 1.7 8.7 5.2 7.7 6.5 0.5 3.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4250) Syntaxin-6_N PF09177.11 KKK15143.1 - 1.9 9.1 37.5 0.82 10.3 11.6 4.4 1 1 2 3 3 3 0 Syntaxin 6, N-terminal HOOK PF05622.12 KKK15143.1 - 3.3 5.7 54.5 1.7 6.7 23.3 3.3 1 1 2 3 3 3 0 HOOK protein MAD PF05557.13 KKK15143.1 - 3.6 5.8 56.1 8.8 4.5 25.0 2.1 1 1 1 2 2 2 0 Mitotic checkpoint protein Baculo_PEP_C PF04513.12 KKK15143.1 - 3.9 7.5 16.3 6.5 6.8 2.1 3.3 2 2 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fib_alpha PF08702.10 KKK15143.1 - 4.7 7.4 36.2 0.087 13.0 3.5 3.9 2 1 2 4 4 4 0 Fibrinogen alpha/beta chain family DUF745 PF05335.13 KKK15143.1 - 4.7 6.9 41.5 1.8 8.2 11.2 3.7 1 1 2 3 3 3 0 Protein of unknown function (DUF745) NPV_P10 PF05531.12 KKK15143.1 - 6.4 7.3 19.1 1.5 9.4 0.6 4.8 2 2 3 5 5 5 0 Nucleopolyhedrovirus P10 protein Carn_acyltransf PF00755.20 KKK15144.1 - 8.2e-206 685.2 0.0 9.3e-206 685.0 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Rxt3 PF08642.10 KKK15145.1 - 4.7e-43 147.0 0.0 1.4e-42 145.5 0.0 1.9 1 0 0 1 1 1 1 Histone deacetylation protein Rxt3 LCCL PF03815.19 KKK15145.1 - 0.0018 18.3 0.0 0.007 16.5 0.0 1.9 1 0 0 1 1 1 1 LCCL domain MFS_1 PF07690.16 KKK15146.1 - 1e-24 87.1 24.4 1e-24 87.1 24.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2046 PF09755.9 KKK15147.1 - 0.0037 16.6 1.4 0.0037 16.6 1.4 2.0 2 0 0 2 2 2 1 Uncharacterized conserved protein H4 (DUF2046) Shugoshin_N PF07558.11 KKK15147.1 - 0.01 15.7 0.1 0.023 14.6 0.1 1.6 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region HOOK PF05622.12 KKK15147.1 - 0.011 13.9 7.6 0.041 12.0 0.4 2.0 2 0 0 2 2 2 0 HOOK protein SKA2 PF16740.5 KKK15147.1 - 0.016 15.0 8.7 0.23 11.3 7.0 2.1 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 DUF3287 PF11690.8 KKK15147.1 - 0.084 12.6 2.2 3 7.6 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3287) DivIC PF04977.15 KKK15147.1 - 0.099 12.4 0.6 0.099 12.4 0.6 2.4 2 1 0 2 2 2 0 Septum formation initiator DUF16 PF01519.16 KKK15147.1 - 0.099 13.1 7.2 3 8.4 4.2 2.2 2 0 0 2 2 2 0 Protein of unknown function DUF16 TMCO5 PF14992.6 KKK15147.1 - 0.2 11.2 4.2 0.58 9.7 0.0 2.0 2 0 0 2 2 2 0 TMCO5 family Atg14 PF10186.9 KKK15147.1 - 0.36 9.9 7.2 0.079 12.0 1.2 2.1 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Fib_alpha PF08702.10 KKK15147.1 - 0.44 10.7 5.1 14 5.8 2.1 2.5 3 0 0 3 3 2 0 Fibrinogen alpha/beta chain family TetR_C_13 PF16925.5 KKK15147.1 - 0.51 10.3 2.5 0.3 11.0 0.5 1.5 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain DMSP_lyase PF16867.5 KKK15147.1 - 0.6 9.7 3.2 0.41 10.3 0.6 2.0 2 0 0 2 2 2 0 Dimethlysulfonioproprionate lyase FlaC_arch PF05377.11 KKK15147.1 - 1.4 9.4 5.1 1.8 9.0 0.1 2.3 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Roughex PF06020.11 KKK15147.1 - 1.4 7.9 6.9 2.4 7.1 6.9 1.3 1 0 0 1 1 1 0 Drosophila roughex protein DUF2968 PF11180.8 KKK15147.1 - 1.8 8.2 18.9 0.18 11.4 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) PRKG1_interact PF15898.5 KKK15147.1 - 3.2 8.7 9.0 5.5 7.9 0.6 2.5 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain SlyX PF04102.12 KKK15147.1 - 4.3 8.0 18.0 6.7 7.4 0.5 2.5 2 0 0 2 2 2 0 SlyX ZapB PF06005.12 KKK15147.1 - 5 7.6 15.0 3.2 8.3 1.0 2.4 2 0 0 2 2 2 0 Cell division protein ZapB BRI3BP PF14965.6 KKK15147.1 - 5.2 6.5 4.2 0.62 9.6 0.2 1.4 2 0 0 2 2 2 0 Negative regulator of p53/TP53 DUF4140 PF13600.6 KKK15147.1 - 7.8 7.0 8.9 9.1 6.8 0.2 2.4 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) CLZ PF16526.5 KKK15147.1 - 9 6.7 10.3 13 6.2 0.2 2.3 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Exo_endo_phos PF03372.23 KKK15148.1 - 3.4e-19 69.3 0.0 6.3e-19 68.4 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_8 PF13855.6 KKK15148.1 - 3e-15 55.7 23.4 7.4e-08 32.1 5.4 2.2 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 KKK15148.1 - 6.2e-11 42.4 7.2 7.7e-08 32.5 1.5 2.4 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KKK15148.1 - 0.12 13.0 5.7 24 6.0 0.1 4.2 4 0 0 4 4 4 0 Leucine Rich Repeat Dynamin_M PF01031.20 KKK15149.1 - 5.1e-111 370.5 0.0 9.8e-111 369.5 0.0 1.5 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.23 KKK15149.1 - 2.4e-55 187.1 0.0 5.8e-55 185.9 0.0 1.7 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 KKK15149.1 - 2e-31 108.0 1.1 5.3e-31 106.6 1.1 1.8 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 KKK15149.1 - 0.00018 21.6 0.2 0.0036 17.4 0.2 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase MAGE_N PF12440.8 KKK15149.1 - 0.0021 18.7 1.7 0.0021 18.7 1.7 2.0 2 0 0 2 2 2 1 Melanoma associated antigen family N terminal FeoB_N PF02421.18 KKK15149.1 - 0.071 12.6 0.1 5.3 6.6 0.0 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B UAA PF08449.11 KKK15150.1 - 5.8e-84 281.9 17.4 3.5e-83 279.3 17.4 1.8 1 1 0 1 1 1 1 UAA transporter family Nuc_sug_transp PF04142.15 KKK15150.1 - 0.00013 21.3 0.7 0.00013 21.3 0.7 2.2 2 0 0 2 2 2 1 Nucleotide-sugar transporter LAGLIDADG_3 PF14528.6 KKK15150.1 - 0.17 12.2 0.0 0.48 10.8 0.0 1.7 1 0 0 1 1 1 0 LAGLIDADG-like domain TPT PF03151.16 KKK15150.1 - 2.1 7.6 17.6 1.3 8.3 2.6 3.4 2 1 0 2 2 2 0 Triose-phosphate Transporter family Rad17 PF03215.15 KKK15151.1 - 1.7e-28 99.8 0.0 3.3e-28 98.9 0.0 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 KKK15151.1 - 0.0012 19.2 0.0 0.0031 17.9 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 KKK15151.1 - 0.017 15.5 0.0 0.041 14.3 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 KKK15151.1 - 0.04 13.0 0.0 0.071 12.2 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein ABC_tran PF00005.27 KKK15151.1 - 0.045 14.3 0.0 0.13 12.8 0.0 1.8 1 0 0 1 1 1 0 ABC transporter AAA_22 PF13401.6 KKK15151.1 - 0.057 13.7 0.0 0.15 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KKK15151.1 - 0.057 13.1 0.0 0.15 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KKK15151.1 - 0.057 13.8 0.0 0.45 10.9 0.0 2.3 2 0 0 2 2 2 0 RNA helicase RsgA_GTPase PF03193.16 KKK15151.1 - 0.11 12.4 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_5 PF07728.14 KKK15151.1 - 0.17 11.9 0.0 0.43 10.6 0.0 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) ELMO_CED12 PF04727.13 KKK15152.1 - 2.5e-51 174.3 0.1 3.8e-51 173.7 0.1 1.3 1 0 0 1 1 1 1 ELMO/CED-12 family PH_12 PF16457.5 KKK15152.1 - 6.3e-34 117.4 0.0 3.6e-33 114.9 0.0 2.4 3 1 0 3 3 3 1 Pleckstrin homology domain DUF3361 PF11841.8 KKK15152.1 - 2.1e-16 60.3 0.1 6.2e-16 58.7 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3361) A_deaminase PF00962.22 KKK15154.1 - 2.7e-122 408.2 0.0 3.7e-122 407.8 0.0 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase SH3_9 PF14604.6 KKK15155.1 - 1.2e-26 92.3 5.1 6e-14 51.6 0.4 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 KKK15155.1 - 3e-26 90.8 4.5 1.4e-14 53.4 0.5 2.5 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.17 KKK15155.1 - 1e-16 60.3 0.1 1e-06 28.3 0.0 3.1 3 0 0 3 3 3 2 Variant SH3 domain Cofilin_ADF PF00241.20 KKK15155.1 - 3.8e-15 55.8 0.0 8.4e-15 54.6 0.0 1.6 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Trypan_PARP PF05887.11 KKK15155.1 - 0.002 18.1 3.3 0.002 18.1 3.3 4.1 3 1 0 4 4 4 1 Procyclic acidic repetitive protein (PARP) Sec10 PF07393.11 KKK15157.1 - 2.8e-241 802.9 0.0 3.2e-241 802.7 0.0 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 MarR_2 PF12802.7 KKK15157.1 - 0.0025 17.7 0.2 0.42 10.5 0.0 2.9 2 0 0 2 2 2 1 MarR family Motilin_assoc PF04643.12 KKK15157.1 - 0.15 11.9 1.5 1.6 8.6 0.1 2.6 2 0 0 2 2 2 0 Motilin/ghrelin-associated peptide Tropomyosin PF00261.20 KKK15157.1 - 0.21 10.9 2.8 0.54 9.6 0.2 2.5 2 0 0 2 2 2 0 Tropomyosin GBP_C PF02841.14 KKK15157.1 - 0.5 9.7 3.1 0.81 9.0 0.0 2.6 3 0 0 3 3 3 0 Guanylate-binding protein, C-terminal domain Sortilin-Vps10 PF15902.5 KKK15158.1 - 1.9e-289 959.7 1.7 5.3e-149 496.8 0.0 2.1 2 0 0 2 2 2 2 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 KKK15158.1 - 1.4e-84 282.6 24.0 2e-44 151.9 1.6 2.7 3 0 0 3 3 3 2 Sortilin, neurotensin receptor 3, C-terminal BNR PF02012.20 KKK15158.1 - 4e-08 32.1 39.2 0.99 9.7 0.0 12.2 13 0 0 13 13 13 4 BNR/Asp-box repeat BNR_2 PF13088.6 KKK15158.1 - 6e-07 29.0 3.7 5.3 6.3 0.0 6.8 6 1 1 7 7 7 3 BNR repeat-like domain PSII_BNR PF14870.6 KKK15158.1 - 1.8e-06 27.4 4.2 0.014 14.6 0.0 6.0 5 2 2 7 7 7 1 Photosynthesis system II assembly factor YCF48 BNR_6 PF15899.5 KKK15158.1 - 0.00017 21.4 4.0 2.2 8.6 0.0 5.5 5 0 0 5 5 5 1 BNR-Asp box repeat CHB_HEX_C PF03174.13 KKK15158.1 - 0.0099 15.8 0.4 6.2 6.9 0.1 3.9 4 0 0 4 4 4 1 Chitobiase/beta-hexosaminidase C-terminal domain DUF4926 PF16277.5 KKK15158.1 - 0.051 12.9 0.0 0.54 9.7 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4926) Mo-co_dimer PF03404.16 KKK15158.1 - 0.15 12.0 2.8 8.8 6.3 0.0 5.0 7 0 0 7 7 7 0 Mo-co oxidoreductase dimerisation domain preSET_CXC PF18264.1 KKK15158.1 - 3.6 8.1 8.3 3.9 8.0 0.5 2.8 2 0 0 2 2 2 0 CXC domain Ytp1 PF10355.9 KKK15160.1 - 2.2e-115 384.6 9.5 3e-115 384.2 9.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 KKK15160.1 - 8.4e-20 70.5 10.2 3.7e-18 65.2 2.4 2.8 2 0 0 2 2 2 2 Domain of unknown function (DUF2427) DUF3500 PF12006.8 KKK15161.1 - 1.2e-110 369.7 0.0 1.4e-110 369.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3500) CTP_synth_N PF06418.14 KKK15162.1 - 4e-121 403.4 0.1 5.2e-121 403.0 0.1 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 KKK15162.1 - 2.9e-53 180.5 0.0 6.4e-53 179.4 0.0 1.6 2 0 0 2 2 2 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 KKK15162.1 - 9.5e-05 22.2 0.2 0.00062 19.6 0.2 2.3 2 1 0 2 2 2 1 Peptidase C26 CbiA PF01656.23 KKK15162.1 - 0.082 13.0 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain adh_short PF00106.25 KKK15163.1 - 3.6e-28 98.4 0.0 8.2e-21 74.4 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KKK15163.1 - 1.6e-14 54.1 0.0 2.2e-12 47.1 0.0 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KKK15163.1 - 1.9e-07 31.1 0.0 4.4e-07 30.0 0.0 1.6 1 1 1 2 2 2 1 KR domain Epimerase PF01370.21 KKK15163.1 - 0.1 12.0 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family UPF0160 PF03690.13 KKK15164.1 - 1.9e-125 418.7 0.0 2.2e-125 418.5 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) BLM10_mid PF16507.5 KKK15165.1 - 9e-205 681.3 0.0 1.4e-204 680.6 0.0 1.3 1 0 0 1 1 1 1 Proteasome-substrate-size regulator, mid region DUF3437 PF11919.8 KKK15165.1 - 5.5e-29 99.9 0.0 4.6e-28 97.0 0.0 2.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3437) CLASP_N PF12348.8 KKK15165.1 - 4e-07 29.8 0.1 0.012 15.2 0.0 3.3 3 0 0 3 3 3 2 CLASP N terminal HEAT PF02985.22 KKK15165.1 - 0.042 14.1 0.1 3.2 8.3 0.0 4.3 4 0 0 4 4 4 0 HEAT repeat NMN_transporter PF04973.12 KKK15165.1 - 0.09 12.7 0.1 0.97 9.4 0.0 2.2 2 0 0 2 2 2 0 Nicotinamide mononucleotide transporter V_ATPase_I PF01496.19 KKK15166.1 - 0 1077.2 0.0 0 1077.0 0.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family CheZ PF04344.13 KKK15166.1 - 0.0021 18.0 0.9 0.039 13.9 0.1 2.4 2 0 0 2 2 2 1 Chemotaxis phosphatase, CheZ DUF1515 PF07439.11 KKK15166.1 - 0.0066 16.5 0.1 0.018 15.1 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1515) Filament PF00038.21 KKK15166.1 - 0.0067 16.0 4.9 0.37 10.3 1.0 2.3 2 0 0 2 2 2 2 Intermediate filament protein CdvA PF18822.1 KKK15166.1 - 0.053 13.4 3.6 10 5.9 0.6 3.3 2 1 0 2 2 2 0 CdvA-like coiled-coil domain Fmp27_WPPW PF10359.9 KKK15166.1 - 0.057 12.3 2.8 0.18 10.6 0.9 2.0 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain DUF1664 PF07889.12 KKK15166.1 - 0.071 13.2 0.8 9.7 6.3 0.1 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Serine_rich PF08824.10 KKK15166.1 - 0.088 12.8 2.0 0.39 10.7 0.3 2.2 2 0 0 2 2 2 0 Serine rich protein interaction domain DUF3552 PF12072.8 KKK15166.1 - 0.089 12.2 2.0 5 6.5 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) DUF4988 PF16378.5 KKK15166.1 - 0.13 11.9 0.2 0.29 10.8 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function ZapB PF06005.12 KKK15166.1 - 0.17 12.4 1.5 2 8.9 0.1 2.5 2 0 0 2 2 2 0 Cell division protein ZapB DASH_Dam1 PF08653.10 KKK15166.1 - 0.27 11.1 1.9 22 5.0 0.0 3.9 4 0 0 4 4 4 0 DASH complex subunit Dam1 Nup54 PF13874.6 KKK15166.1 - 0.36 10.9 1.8 2.2 8.4 0.2 2.3 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 Prefoldin_2 PF01920.20 KKK15166.1 - 0.48 10.4 3.7 0.93 9.5 0.3 2.7 3 0 0 3 3 3 0 Prefoldin subunit CorA PF01544.18 KKK15166.1 - 0.62 9.3 3.8 5.5 6.2 0.6 2.6 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein HMMR_N PF15905.5 KKK15166.1 - 0.96 8.9 3.0 4.2 6.8 0.4 2.2 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal Tektin PF03148.14 KKK15166.1 - 0.98 8.1 7.8 1.1 7.9 1.8 2.4 2 1 0 2 2 2 0 Tektin family DivIC PF04977.15 KKK15166.1 - 1.2 9.0 4.9 0.59 9.9 0.4 2.7 2 0 0 2 2 2 0 Septum formation initiator Peptidase_M24 PF00557.24 KKK15167.1 - 2e-41 142.0 0.1 2.7e-41 141.6 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 Glyco_transf_54 PF04666.13 KKK15168.1 - 4.5e-11 42.2 0.2 6.6e-05 21.9 0.0 3.1 3 0 0 3 3 3 3 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region DUF543 PF04418.12 KKK15169.1 - 6.9e-28 96.5 0.0 8e-28 96.2 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF543) Urb2 PF10441.9 KKK15170.1 - 9.4e-66 221.6 0.2 6.9e-65 218.8 0.0 2.6 2 0 0 2 2 2 1 Urb2/Npa2 family Copper-fist PF00649.18 KKK15171.1 - 3.3e-18 64.9 0.3 9.2e-18 63.5 0.3 1.9 1 0 0 1 1 1 1 Copper fist DNA binding domain Transp_cyt_pur PF02133.15 KKK15172.1 - 2.1e-150 501.3 32.4 2.5e-150 501.1 32.4 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin RVT_1 PF00078.27 KKK15173.1 - 0.00026 20.6 0.0 0.00055 19.5 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SnoaL PF07366.12 KKK15174.1 - 8.4e-05 22.4 0.0 0.0002 21.1 0.0 1.6 2 0 0 2 2 2 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 KKK15174.1 - 0.00042 20.9 0.0 0.001 19.7 0.0 1.7 1 0 0 1 1 1 1 SnoaL-like domain Med4 PF10018.9 KKK15175.1 - 5e-58 196.0 0.2 8.1e-58 195.3 0.0 1.4 2 0 0 2 2 2 1 Vitamin-D-receptor interacting Mediator subunit 4 DUF2193 PF09959.9 KKK15175.1 - 0.032 12.7 0.1 0.042 12.3 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2193) adh_short_C2 PF13561.6 KKK15176.1 - 5.5e-56 189.7 1.6 7.5e-56 189.3 1.6 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KKK15176.1 - 5.4e-48 163.0 1.7 6.6e-48 162.8 1.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KKK15176.1 - 2e-10 40.9 0.6 2.8e-10 40.4 0.6 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 KKK15176.1 - 0.009 15.4 0.0 0.012 15.0 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) 2-Hacid_dh_C PF02826.19 KKK15176.1 - 0.032 13.6 0.2 0.22 10.8 0.1 2.0 1 1 1 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ORC2 PF04084.14 KKK15176.1 - 0.11 11.3 0.0 0.18 10.7 0.0 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 2 FAD_binding_3 PF01494.19 KKK15177.1 - 2.8e-09 36.7 0.0 1.7e-08 34.2 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KKK15177.1 - 1.6e-06 28.0 0.0 0.039 13.5 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KKK15177.1 - 0.0076 15.5 0.0 0.31 10.2 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KKK15177.1 - 0.015 14.4 0.0 0.022 13.8 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 KKK15177.1 - 0.2 10.3 0.0 1.2 7.8 0.1 1.9 2 0 0 2 2 2 0 HI0933-like protein EthD PF07110.11 KKK15178.1 - 5e-21 75.7 0.4 6.1e-21 75.4 0.4 1.1 1 0 0 1 1 1 1 EthD domain ketoacyl-synt PF00109.26 KKK15179.1 - 1.2e-68 231.4 0.0 2e-68 230.7 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain SAT PF16073.5 KKK15179.1 - 1.7e-46 159.0 0.0 8.4e-46 156.6 0.0 2.1 2 0 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Acyl_transf_1 PF00698.21 KKK15179.1 - 1.3e-43 149.7 0.1 9.5e-43 146.9 0.0 2.1 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KKK15179.1 - 6.3e-34 116.5 0.8 2.1e-33 114.8 0.8 2.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.25 KKK15179.1 - 1.4e-11 44.6 0.6 4e-11 43.1 0.6 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site PS-DH PF14765.6 KKK15179.1 - 3.3e-09 36.4 0.0 9.2e-09 34.9 0.0 1.8 1 0 0 1 1 1 1 Polyketide synthase dehydratase KAsynt_C_assoc PF16197.5 KKK15179.1 - 1.7e-07 31.7 0.1 7.3e-07 29.6 0.0 2.1 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension Raf1_HTH PF18579.1 KKK15179.1 - 0.19 11.5 0.0 0.44 10.3 0.0 1.7 1 0 0 1 1 1 0 Rubisco accumulation factor 1 helix turn helix domain Thiolase_N PF00108.23 KKK15179.1 - 0.21 10.9 0.8 0.45 9.8 0.8 1.5 1 0 0 1 1 1 0 Thiolase, N-terminal domain DUF1772 PF08592.11 KKK15180.1 - 3.2e-31 108.4 9.5 3.8e-31 108.2 9.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) ApoO PF09769.9 KKK15180.1 - 0.054 13.4 0.3 0.054 13.4 0.3 1.9 3 0 0 3 3 3 0 Apolipoprotein O Lactamase_B PF00753.27 KKK15181.1 - 4.3e-17 62.8 7.2 2.3e-15 57.1 7.2 2.2 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KKK15181.1 - 4.2e-05 23.1 1.2 0.00011 21.7 1.2 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain BLACT_WH PF17778.1 KKK15181.1 - 0.00015 21.7 0.4 0.0025 17.8 0.0 2.9 3 0 0 3 3 3 1 Beta-lactamase associated winged helix domain AflR PF08493.10 KKK15182.1 - 1.9e-33 116.2 5.3 5.1e-33 114.8 5.3 1.6 1 1 0 1 1 1 1 Aflatoxin regulatory protein Zn_clus PF00172.18 KKK15182.1 - 4.2e-07 30.0 8.9 7.3e-07 29.2 8.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_M14 PF00246.24 KKK15183.1 - 1.1e-74 251.8 0.0 1.6e-74 251.3 0.0 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase Ribosomal_60s PF00428.19 KKK15183.1 - 0.013 16.1 5.1 0.025 15.1 5.1 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein Mito_carr PF00153.27 KKK15207.1 - 7.5e-60 198.9 2.4 1.9e-19 69.3 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein RTA1 PF04479.13 KKK15208.1 - 1.3e-71 240.5 5.1 1.9e-71 240.0 5.1 1.1 1 0 0 1 1 1 1 RTA1 like protein PhrC_PhrF PF11131.8 KKK15208.1 - 0.077 12.6 0.4 0.29 10.8 0.4 1.9 1 0 0 1 1 1 0 Rap-phr extracellular signalling UQ_con PF00179.26 KKK15209.1 - 1.1e-43 148.2 0.0 1.3e-43 148.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KKK15209.1 - 1.8 8.9 3.8 3.2 8.1 3.8 1.6 1 1 0 1 1 1 0 RWD domain TNT PF14021.6 KKK15211.1 - 1.7e-33 115.0 0.1 3.5e-33 114.0 0.0 1.5 2 0 0 2 2 2 1 Tuberculosis necrotizing toxin ADH_N PF08240.12 KKK15212.1 - 1.1e-05 25.2 0.0 2.9e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KKK15212.1 - 0.00057 19.9 0.1 0.00094 19.2 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase CDO_I PF05995.12 KKK15213.1 - 1.9e-32 111.9 0.4 3.3e-16 59.1 0.0 3.1 2 1 1 3 3 3 3 Cysteine dioxygenase type I PCO_ADO PF07847.12 KKK15213.1 - 0.0012 18.4 0.0 0.0017 17.9 0.0 1.3 1 0 0 1 1 1 1 PCO_ADO MMR_HSR1_Xtn PF16897.5 KKK15214.1 - 7.3e-40 135.3 0.7 2.2e-39 133.7 0.2 1.9 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 KKK15214.1 - 4.7e-21 75.0 0.1 1.1e-20 73.9 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase TGS PF02824.21 KKK15214.1 - 5.7e-19 67.9 0.0 1.4e-18 66.6 0.0 1.7 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.18 KKK15214.1 - 5.7e-10 38.9 0.1 3.1e-09 36.5 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 KKK15214.1 - 0.00047 19.7 0.2 4.3 6.8 0.0 3.8 2 2 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 KKK15214.1 - 0.001 19.1 0.3 0.22 11.6 0.0 2.3 1 1 1 2 2 2 2 Dynamin family MeaB PF03308.16 KKK15214.1 - 0.0084 15.1 0.1 0.017 14.1 0.1 1.5 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Arf PF00025.21 KKK15214.1 - 0.032 13.7 0.2 2.2 7.7 0.0 2.2 2 0 0 2 2 2 0 ADP-ribosylation factor family RsgA_GTPase PF03193.16 KKK15214.1 - 0.065 13.1 1.3 2.8 7.8 0.1 2.9 2 1 1 3 3 3 0 RsgA GTPase TGT PF01702.18 KKK15215.1 - 4.5e-128 427.3 0.0 6.7e-127 423.4 0.0 2.0 1 1 0 1 1 1 1 Queuine tRNA-ribosyltransferase Thymidylat_synt PF00303.19 KKK15215.1 - 1.6e-99 332.4 0.0 2.1e-99 332.0 0.0 1.2 1 0 0 1 1 1 1 Thymidylate synthase zf-AN1 PF01428.16 KKK15216.1 - 6.5e-16 58.2 20.0 5.5e-12 45.7 8.4 2.5 3 0 0 3 3 3 2 AN1-like Zinc finger Transp_Tc5_C PF04236.15 KKK15216.1 - 1.9 8.9 11.2 0.047 14.1 4.0 2.0 2 1 0 2 2 2 0 Tc5 transposase C-terminal domain C1_4 PF07975.12 KKK15216.1 - 2.7 8.3 9.3 0.5 10.6 4.3 2.2 2 0 0 2 2 2 0 TFIIH C1-like domain Hist_deacetyl PF00850.19 KKK15217.1 - 4.6e-23 82.2 0.0 7.5e-23 81.5 0.0 1.4 1 0 0 1 1 1 1 Histone deacetylase domain RTP801_C PF07809.11 KKK15217.1 - 0.019 14.9 0.0 0.039 13.9 0.0 1.4 1 0 0 1 1 1 0 RTP801 C-terminal region INSC_LBD PF16748.5 KKK15218.1 - 0.03 13.8 0.1 0.057 12.9 0.1 1.4 1 0 0 1 1 1 0 Inscuteable LGN-binding domain CDC45 PF02724.14 KKK15219.1 - 1.3 7.2 5.7 1.7 6.9 5.7 1.1 1 0 0 1 1 1 0 CDC45-like protein MFS_1 PF07690.16 KKK15221.1 - 1.8e-27 96.2 27.5 2.1e-27 96.0 27.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily zf-H2C2_2 PF13465.6 KKK15225.1 - 2.3e-09 37.2 7.2 0.00044 20.5 0.1 3.1 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.26 KKK15225.1 - 2.4e-05 24.5 23.5 0.008 16.6 6.8 4.1 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KKK15225.1 - 0.00044 20.8 21.1 0.057 14.3 5.2 4.4 4 0 0 4 4 4 3 C2H2-type zinc finger MSL1_dimer PF16801.5 KKK15225.1 - 0.086 12.6 5.3 0.17 11.7 5.3 1.4 1 0 0 1 1 1 0 Dimerisation domain of Male-specific-Lethal 1 zf-C2H2_11 PF16622.5 KKK15225.1 - 0.81 9.5 6.7 9.6 6.1 2.1 2.6 2 0 0 2 2 2 0 zinc-finger C2H2-type Bunya_G2 PF03563.13 KKK15225.1 - 1.6 7.9 3.8 2.6 7.2 3.8 1.2 1 0 0 1 1 1 0 Bunyavirus glycoprotein G2 zf-C2H2_6 PF13912.6 KKK15225.1 - 4.1 7.5 8.6 26 5.0 0.1 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger CP2 PF04516.15 KKK15226.1 - 1.6e-90 302.4 0.0 2.8e-90 301.7 0.0 1.4 1 0 0 1 1 1 1 CP2 transcription factor Clathrin PF00637.20 KKK15227.1 - 1.3e-21 76.9 0.3 4.3e-19 68.8 0.1 3.2 2 1 1 3 3 3 1 Region in Clathrin and VPS Vps39_1 PF10366.9 KKK15227.1 - 0.013 15.7 0.1 0.039 14.2 0.1 1.7 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 1 PQQ_3 PF13570.6 KKK15227.1 - 0.018 15.5 0.2 0.32 11.5 0.0 2.8 2 0 0 2 2 2 0 PQQ-like domain TPR_14 PF13428.6 KKK15227.1 - 0.057 14.3 2.0 5.9 8.0 0.2 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 KKK15227.1 - 0.061 13.4 0.5 4.5 7.5 0.2 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 KKK15227.1 - 0.073 13.2 0.1 2.6 8.4 0.6 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat WD40_like PF17005.5 KKK15227.1 - 0.077 12.3 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 WD40-like domain zf-RING_5 PF14634.6 KKK15227.1 - 0.16 12.0 0.8 0.32 11.0 0.8 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_11 PF17123.5 KKK15227.1 - 0.39 10.5 1.6 0.96 9.3 1.6 1.7 1 0 0 1 1 1 0 RING-like zinc finger DUF155 PF02582.14 KKK15228.1 - 1.3e-47 162.2 0.0 1.8e-47 161.7 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Ribonuclease_T2 PF00445.18 KKK15229.1 - 4.6e-44 150.8 0.9 8.4e-44 150.0 0.9 1.4 1 0 0 1 1 1 1 Ribonuclease T2 family GT-D PF08759.11 KKK15229.1 - 0.076 12.7 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase GT-D fold MFS_1 PF07690.16 KKK15230.1 - 7.3e-18 64.6 34.6 1.7e-15 56.9 29.9 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.13 KKK15230.1 - 5.1e-17 62.2 1.8 5.1e-17 62.2 1.8 1.7 2 0 0 2 2 2 1 Nodulin-like Serinc PF03348.15 KKK15231.1 - 1.4e-153 511.8 10.1 1.7e-153 511.6 10.1 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) DUF21 PF01595.20 KKK15231.1 - 0.0074 16.0 0.4 0.0074 16.0 0.4 4.1 3 1 1 4 4 4 1 Cyclin M transmembrane N-terminal domain FeS PF04060.13 KKK15231.1 - 0.27 10.9 3.9 0.58 9.9 3.9 1.5 1 0 0 1 1 1 0 Putative Fe-S cluster DUF3492 PF11997.8 KKK15232.1 - 0.0078 16.0 0.0 0.016 15.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3492) Lactamase_B PF00753.27 KKK15233.1 - 3e-17 63.3 1.8 4.2e-17 62.8 1.8 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KKK15233.1 - 0.01 15.4 1.4 0.015 14.8 1.4 1.2 1 0 0 1 1 1 0 Beta-lactamase superfamily domain SLAC1 PF03595.17 KKK15234.1 - 1e-93 314.1 55.0 1.2e-93 314.0 55.0 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel Rhodanese PF00581.20 KKK15235.1 - 2.5e-16 60.1 0.0 1e-08 35.6 0.0 2.1 2 0 0 2 2 2 2 Rhodanese-like domain DUF202 PF02656.15 KKK15236.1 - 1e-16 61.1 0.0 2.3e-16 60.0 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF202) DUF2243 PF10002.9 KKK15236.1 - 0.13 12.3 0.1 0.42 10.7 0.0 1.7 2 0 0 2 2 2 0 Predicted membrane protein (DUF2243) Zn_clus PF00172.18 KKK15237.1 - 5.6e-11 42.4 8.1 1.1e-10 41.5 8.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KKK15237.1 - 1.9e-09 37.0 0.6 5e-09 35.6 0.4 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Herpes_UL95 PF03038.14 KKK15237.1 - 0.085 12.0 0.2 0.2 10.8 0.2 1.6 1 1 0 1 1 1 0 UL95 family APH PF01636.23 KKK15238.1 - 2.7e-06 27.5 0.0 5.3e-05 23.3 0.0 2.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KKK15238.1 - 0.087 12.4 1.7 0.15 11.7 0.1 1.9 2 0 0 2 2 2 0 Choline/ethanolamine kinase FKBP_C PF00254.28 KKK15239.1 - 1e-33 115.5 0.0 1.4e-33 115.1 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Glyco_tranf_2_3 PF13641.6 KKK15240.1 - 1.8e-17 64.0 0.0 3.2e-17 63.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 KKK15240.1 - 4.7e-15 56.0 5.6 4.7e-15 56.0 5.6 2.7 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 KKK15240.1 - 8.9e-15 54.9 0.0 1.3e-14 54.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 KKK15240.1 - 2.2e-07 30.5 0.0 3.9e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 21 DUF3759 PF12585.8 KKK15241.1 - 3.1e-40 136.1 6.7 3.7e-40 135.8 6.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) Aa_trans PF01490.18 KKK15242.1 - 1.9e-21 76.3 33.3 2.4e-21 75.9 33.3 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF4401 PF14351.6 KKK15242.1 - 7.2 5.8 34.9 0.08 12.2 12.3 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4401) MFS_1 PF07690.16 KKK15243.1 - 1.4e-28 99.9 26.4 1.4e-28 99.9 26.4 1.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Spherulin4 PF12138.8 KKK15244.1 - 3.5e-69 233.1 2.3 4.1e-69 232.9 2.3 1.0 1 0 0 1 1 1 1 Spherulation-specific family 4 Synaptobrevin PF00957.21 KKK15244.1 - 0.028 14.2 0.3 1.2 9.0 0.6 2.2 2 0 0 2 2 2 0 Synaptobrevin AI-2E_transport PF01594.16 KKK15244.1 - 1.3 8.1 5.1 0.83 8.7 2.9 1.6 2 0 0 2 2 2 0 AI-2E family transporter Lactamase_B PF00753.27 KKK15245.1 - 1.4e-19 70.9 1.5 2e-19 70.4 1.5 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KKK15245.1 - 0.0047 16.5 0.1 0.0075 15.8 0.1 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Pyr_redox_2 PF07992.14 KKK15246.1 - 5.3e-11 42.3 0.0 6.7e-09 35.4 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KKK15246.1 - 0.0027 17.4 0.3 0.0069 16.0 0.2 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KKK15246.1 - 0.0083 16.1 0.0 0.057 13.4 0.0 2.1 2 0 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KKK15246.1 - 0.13 12.5 0.1 0.35 11.1 0.1 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KKK15246.1 - 0.14 11.2 1.2 0.18 10.8 0.3 1.7 2 1 0 2 2 2 0 Lycopene cyclase protein Epimerase PF01370.21 KKK15247.1 - 1.5e-36 126.1 0.0 3.7e-35 121.5 0.0 2.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KKK15247.1 - 1.6e-34 119.8 0.0 3.4e-33 115.4 0.0 2.3 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KKK15247.1 - 2.2e-08 33.5 0.0 4.3e-07 29.2 0.0 2.6 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KKK15247.1 - 5.8e-07 28.9 0.0 1.8e-06 27.3 0.0 1.7 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.15 KKK15247.1 - 3.7e-06 26.3 0.0 0.00012 21.3 0.0 2.9 3 1 0 3 3 3 1 Polysaccharide biosynthesis protein KR PF08659.10 KKK15247.1 - 0.0038 17.2 0.0 0.0096 15.9 0.0 1.6 1 1 0 1 1 1 1 KR domain adh_short PF00106.25 KKK15247.1 - 0.022 14.2 0.0 0.035 13.6 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase Spherulin4 PF12138.8 KKK15248.1 - 4.2e-61 206.6 0.0 4.7e-61 206.5 0.0 1.0 1 0 0 1 1 1 1 Spherulation-specific family 4 Spore_III_AB PF09548.10 KKK15248.1 - 0.23 11.6 0.0 0.35 11.0 0.0 1.2 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) Sugar_tr PF00083.24 KKK15250.1 - 3.6e-79 266.7 26.8 4.3e-79 266.5 26.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKK15250.1 - 5.3e-17 61.8 25.8 5.3e-17 61.8 25.8 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily 7TM_GPCR_Sra PF02117.16 KKK15250.1 - 0.014 14.2 1.2 0.031 13.1 0.2 2.0 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Sra DUF2852 PF11014.8 KKK15250.1 - 0.017 15.3 0.1 0.044 13.9 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2852) Phage_holin_2_4 PF16082.5 KKK15250.1 - 0.5 10.1 2.9 0.4 10.4 0.1 2.3 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like DUF3792 PF12670.7 KKK15250.1 - 0.55 10.4 21.1 2.3 8.4 6.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3792) FixS PF03597.15 KKK15250.1 - 0.74 9.6 0.0 0.74 9.6 0.0 3.5 4 0 0 4 4 4 0 Cytochrome oxidase maturation protein cbb3-type Sugar_tr PF00083.24 KKK15252.1 - 5.4e-92 309.0 17.1 6.5e-92 308.7 17.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKK15252.1 - 1.8e-30 106.1 36.2 1.6e-28 99.7 20.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KKK15252.1 - 3.6e-05 22.4 4.3 3.6e-05 22.4 4.3 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) PTR2 PF00854.21 KKK15252.1 - 0.035 13.0 5.9 0.51 9.1 1.2 2.5 1 1 1 2 2 2 0 POT family OATP PF03137.20 KKK15252.1 - 0.54 8.5 14.3 0.99 7.6 1.9 3.1 1 1 2 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family YtpI PF14007.6 KKK15252.1 - 2 8.6 8.7 0.67 10.1 1.5 3.2 3 0 0 3 3 3 0 YtpI-like protein NTP_transf_9 PF04248.12 KKK15253.1 - 4.1e-29 100.3 0.2 4.6e-29 100.2 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF427) CFEM PF05730.11 KKK15254.1 - 0.02 15.0 11.4 0.13 12.3 11.4 2.3 1 1 0 1 1 1 0 CFEM domain DUF2156 PF09924.9 KKK15256.1 - 5.6e-30 104.4 0.0 8.1e-30 103.9 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2156) CBM_1 PF00734.18 KKK15257.1 - 8.9e-14 51.2 9.1 8.9e-14 51.2 9.1 2.2 2 1 0 2 2 2 1 Fungal cellulose binding domain Lipase_GDSL_2 PF13472.6 KKK15257.1 - 4.5e-12 46.7 0.1 9e-12 45.7 0.1 1.5 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KKK15257.1 - 3.4e-10 40.2 0.0 5.9e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase DPBB_1 PF03330.18 KKK15257.1 - 1.2e-06 28.7 0.4 3.1e-06 27.4 0.4 1.7 1 0 0 1 1 1 1 Lytic transglycolase Lipase_GDSL_3 PF14606.6 KKK15257.1 - 0.046 13.9 0.1 3.1 7.9 0.0 2.2 1 1 1 2 2 2 0 GDSL-like Lipase/Acylhydrolase family JSRP PF15312.6 KKK15257.1 - 0.11 12.4 0.4 0.28 11.1 0.4 1.7 1 0 0 1 1 1 0 Junctional sarcoplasmic reticulum protein Mucin PF01456.17 KKK15257.1 - 0.29 11.1 48.5 0.78 9.7 48.5 1.7 1 0 0 1 1 1 0 Mucin-like glycoprotein Zn_clus PF00172.18 KKK15258.1 - 1e-09 38.4 12.7 1e-09 38.4 12.7 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ABC2_membrane PF01061.24 KKK15259.1 - 6.9e-78 260.9 46.6 8.7e-44 149.5 14.2 2.5 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 KKK15259.1 - 2.5e-38 131.7 0.0 1.7e-18 67.5 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 KKK15259.1 - 1.3e-27 95.5 4.3 8.6e-25 86.5 0.0 3.4 3 0 0 3 3 3 2 CDR ABC transporter AAA_16 PF13191.6 KKK15259.1 - 3.8e-07 30.7 0.1 0.00034 21.1 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain ABC2_membrane_3 PF12698.7 KKK15259.1 - 5.9e-07 28.9 21.5 0.00052 19.2 8.8 2.5 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_25 PF13481.6 KKK15259.1 - 4.8e-05 23.0 0.1 0.0029 17.2 0.1 2.3 2 0 0 2 2 2 1 AAA domain ABC_trans_N PF14510.6 KKK15259.1 - 5.5e-05 23.7 0.0 0.00014 22.4 0.0 1.7 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_18 PF13238.6 KKK15259.1 - 0.0004 20.9 0.0 2.4 8.7 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.6 KKK15259.1 - 0.0004 20.7 0.4 1.1 9.6 0.1 2.9 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KKK15259.1 - 0.00085 19.0 0.3 0.088 12.6 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KKK15259.1 - 0.002 18.0 0.1 0.012 15.5 0.0 2.0 2 0 0 2 2 2 1 RsgA GTPase AAA_33 PF13671.6 KKK15259.1 - 0.0025 18.0 0.1 1.2 9.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 KKK15259.1 - 0.0065 16.7 1.4 1.3 9.2 0.6 2.4 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 KKK15259.1 - 0.014 15.0 1.8 1.9 8.0 0.5 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_21 PF13304.6 KKK15259.1 - 0.033 14.0 0.0 3.2 7.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system NACHT PF05729.12 KKK15259.1 - 0.04 13.8 0.7 3 7.7 0.1 2.3 2 0 0 2 2 2 0 NACHT domain AAA_30 PF13604.6 KKK15259.1 - 0.086 12.6 0.8 7.4 6.2 0.2 2.3 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 KKK15259.1 - 0.13 12.7 0.1 20 5.6 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.6 KKK15259.1 - 0.18 12.2 0.3 7.8 6.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 KKK15259.1 - 0.23 11.2 0.6 9.1 6.0 0.2 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF805 PF05656.14 KKK15259.1 - 1.1 9.7 8.7 12 6.4 0.8 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF805) Fungal_trans_2 PF11951.8 KKK15283.1 - 5.8e-08 31.9 0.0 7.6e-08 31.6 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain G_glu_transpept PF01019.21 KKK15284.1 - 1.1e-160 535.8 0.2 1.5e-160 535.4 0.2 1.2 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase TPP_enzyme_N PF02776.18 KKK15284.1 - 4.1e-36 124.2 0.0 8.8e-36 123.1 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain ADH_N PF08240.12 KKK15284.1 - 4.5e-28 97.3 7.2 1e-27 96.1 7.2 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KKK15284.1 - 7.1e-17 61.6 0.5 2.2e-16 60.0 0.5 1.9 1 0 0 1 1 1 1 Zinc-binding dehydrogenase TPP_enzyme_C PF02775.21 KKK15284.1 - 1.2e-16 60.9 0.1 3.4e-16 59.4 0.1 1.8 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 KKK15284.1 - 3.5e-16 59.2 0.0 7.7e-16 58.1 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain ADH_zinc_N_2 PF13602.6 KKK15284.1 - 0.00023 22.2 0.3 0.00083 20.4 0.3 2.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AATase PF07247.12 KKK15285.1 - 0.0012 17.5 0.0 0.0027 16.3 0.0 1.5 1 1 0 1 1 1 1 Alcohol acetyltransferase Tri3 PF07428.11 KKK15285.1 - 0.016 14.2 0.0 0.083 11.8 0.0 1.8 2 0 0 2 2 2 0 15-O-acetyltransferase Tri3 HhH-GPD PF00730.25 KKK15287.1 - 6e-07 29.9 0.0 3.1e-06 27.6 0.0 2.2 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein IL6 PF00489.17 KKK15287.1 - 0.16 11.5 0.9 0.37 10.4 0.7 1.7 1 1 0 1 1 1 0 Interleukin-6/G-CSF/MGF family DIL PF01843.19 KKK15288.1 - 2.2e-31 108.2 0.7 5.2e-31 107.0 0.7 1.7 1 0 0 1 1 1 1 DIL domain Ank_4 PF13637.6 KKK15288.1 - 2.4e-08 34.3 0.2 5.1e-05 23.7 0.0 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KKK15288.1 - 1.9e-07 31.6 0.1 5.9e-07 30.0 0.0 1.9 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KKK15288.1 - 3.5e-07 30.4 0.0 8.6e-07 29.1 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 KKK15288.1 - 3e-05 24.2 0.1 0.0065 16.9 0.0 3.0 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.6 KKK15288.1 - 0.0012 19.2 0.2 0.0069 16.8 0.0 2.5 3 0 0 3 3 3 1 Ankyrin repeat DUF2722 PF10846.8 KKK15289.1 - 2.2e-06 26.9 0.0 2.2e-06 26.9 0.0 2.4 1 1 0 2 2 2 1 Protein of unknown function (DUF2722) RabGAP-TBC PF00566.18 KKK15290.1 - 1e-34 120.1 0.1 2.6e-34 118.7 0.0 1.7 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Fructosamin_kin PF03881.14 KKK15290.1 - 0.12 11.6 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 Fructosamine kinase Mo25 PF08569.11 KKK15291.1 - 4.1e-134 447.1 0.0 4.7e-134 446.9 0.0 1.0 1 0 0 1 1 1 1 Mo25-like DLIC PF05783.11 KKK15291.1 - 0.075 11.9 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) Methyltransf_25 PF13649.6 KKK15292.1 - 3e-10 40.7 0.0 7.3e-10 39.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KKK15292.1 - 6.6e-09 36.3 0.0 1.5e-08 35.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KKK15292.1 - 2.7e-08 33.6 0.1 5.5e-08 32.5 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 KKK15292.1 - 3.1e-08 33.5 0.0 5.9e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 KKK15292.1 - 4.7e-05 23.4 0.1 9.3e-05 22.4 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KKK15292.1 - 0.0001 22.2 0.0 0.00019 21.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KKK15292.1 - 0.00016 21.3 0.1 0.00028 20.5 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_9 PF08003.11 KKK15292.1 - 0.003 16.6 0.0 0.0072 15.3 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) TehB PF03848.14 KKK15292.1 - 0.0081 15.6 0.1 0.015 14.7 0.1 1.4 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_12 PF08242.12 KKK15292.1 - 0.025 15.3 0.0 0.073 13.8 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain CMAS PF02353.20 KKK15292.1 - 0.045 13.0 0.0 0.09 12.1 0.0 1.4 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase PCMT PF01135.19 KKK15292.1 - 0.059 13.1 0.1 0.15 11.8 0.0 1.6 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.18 KKK15292.1 - 0.066 12.5 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_24 PF13578.6 KKK15292.1 - 0.073 14.1 0.0 0.17 12.9 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Met_10 PF02475.16 KKK15292.1 - 0.1 12.3 0.1 0.21 11.3 0.1 1.4 1 0 0 1 1 1 0 Met-10+ like-protein PRMT5 PF05185.16 KKK15292.1 - 0.16 11.8 0.4 2.3 8.0 0.0 2.2 2 0 0 2 2 2 0 PRMT5 arginine-N-methyltransferase DUF5636 PF18686.1 KKK15292.1 - 0.18 12.0 0.1 0.18 12.0 0.1 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5636) Cir_N PF10197.9 KKK15293.1 - 1.6e-07 31.4 8.4 1.6e-07 31.4 8.4 3.6 4 0 0 4 4 4 1 N-terminal domain of CBF1 interacting co-repressor CIR FANCI_HD2 PF14680.6 KKK15293.1 - 0.052 12.8 0.1 0.1 11.8 0.1 1.4 1 0 0 1 1 1 0 FANCI helical domain 2 AAA PF00004.29 KKK15294.1 - 4.7e-55 185.6 0.1 7e-38 130.0 0.0 2.9 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) CDC48_2 PF02933.17 KKK15294.1 - 1.5e-10 40.7 0.3 2.9e-09 36.6 0.0 2.7 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 AAA_22 PF13401.6 KKK15294.1 - 1.7e-09 38.0 0.2 0.00025 21.3 0.0 4.2 2 2 0 2 2 2 2 AAA domain AAA_lid_3 PF17862.1 KKK15294.1 - 8.1e-09 35.1 0.0 2e-08 33.9 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 KKK15294.1 - 1.5e-08 35.2 0.0 0.0038 17.6 0.0 3.5 2 1 0 3 3 3 2 AAA ATPase domain CDC48_N PF02359.18 KKK15294.1 - 3.8e-08 33.4 0.0 1.2e-07 31.8 0.0 1.8 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_2 PF07724.14 KKK15294.1 - 2e-07 31.3 0.2 4.3e-05 23.7 0.0 2.9 3 0 0 3 3 2 1 AAA domain (Cdc48 subfamily) AAA_18 PF13238.6 KKK15294.1 - 2.8e-07 31.1 0.0 0.02 15.5 0.0 3.8 4 0 0 4 4 3 2 AAA domain AAA_24 PF13479.6 KKK15294.1 - 6.3e-07 29.3 0.0 0.018 14.8 0.0 2.7 2 1 0 2 2 2 2 AAA domain ATPase_2 PF01637.18 KKK15294.1 - 8.7e-07 29.1 1.2 0.56 10.1 0.1 4.1 3 1 1 4 4 4 2 ATPase domain predominantly from Archaea Mg_chelatase PF01078.21 KKK15294.1 - 1.1e-06 28.2 0.0 0.0053 16.2 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 KKK15294.1 - 1.2e-06 28.4 0.0 0.033 13.9 0.0 2.7 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KKK15294.1 - 1.4e-06 28.3 0.0 0.0016 18.4 0.0 2.9 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 KKK15294.1 - 5.6e-06 26.6 0.0 0.11 12.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.13 KKK15294.1 - 7.7e-06 25.3 0.2 0.029 13.6 0.0 2.6 3 0 0 3 3 3 2 TIP49 P-loop domain RNA_helicase PF00910.22 KKK15294.1 - 4.2e-05 23.9 0.0 0.11 12.9 0.0 2.8 2 0 0 2 2 2 2 RNA helicase AAA_14 PF13173.6 KKK15294.1 - 8.3e-05 22.6 0.0 0.19 11.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 KKK15294.1 - 0.00031 20.3 0.4 0.02 14.4 0.0 2.8 3 0 0 3 3 3 1 P-loop containing dynein motor region TniB PF05621.11 KKK15294.1 - 0.00033 20.1 0.2 1.8 7.9 0.0 3.8 3 1 0 3 3 3 1 Bacterial TniB protein ATPase PF06745.13 KKK15294.1 - 0.0004 19.8 1.3 0.035 13.5 0.2 3.0 2 1 1 3 3 3 1 KaiC AAA_25 PF13481.6 KKK15294.1 - 0.00044 19.9 0.5 1.3 8.5 0.0 3.1 2 2 2 4 4 4 2 AAA domain IstB_IS21 PF01695.17 KKK15294.1 - 0.00062 19.6 0.0 0.1 12.3 0.0 2.7 2 0 0 2 2 2 1 IstB-like ATP binding protein TsaE PF02367.17 KKK15294.1 - 0.0025 17.8 0.0 0.39 10.7 0.0 2.7 2 1 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 KKK15294.1 - 0.003 17.8 0.0 1.3 9.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 KKK15294.1 - 0.0034 17.9 0.2 0.016 15.7 0.1 2.1 2 0 0 2 2 1 1 ABC transporter Parvo_NS1 PF01057.17 KKK15294.1 - 0.0043 16.2 0.1 0.48 9.5 0.0 2.3 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 Sigma54_activat PF00158.26 KKK15294.1 - 0.011 15.5 0.1 0.65 9.7 0.0 2.8 3 0 0 3 3 2 0 Sigma-54 interaction domain AAA_17 PF13207.6 KKK15294.1 - 0.018 15.5 0.0 6.4 7.2 0.0 2.8 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 KKK15294.1 - 0.018 14.5 1.0 2.1 7.8 0.0 2.7 3 0 0 3 3 2 0 PhoH-like protein AAA_19 PF13245.6 KKK15294.1 - 0.03 14.7 0.4 0.67 10.3 0.0 2.9 2 1 1 3 3 3 0 AAA domain NB-ARC PF00931.22 KKK15294.1 - 0.032 13.4 0.0 1.9 7.6 0.1 2.6 2 1 1 3 3 3 0 NB-ARC domain IPT PF01745.16 KKK15294.1 - 0.032 13.6 0.0 0.67 9.3 0.0 2.7 2 1 1 3 3 3 0 Isopentenyl transferase NACHT PF05729.12 KKK15294.1 - 0.037 14.0 0.0 5.5 6.9 0.0 3.0 3 1 0 3 3 2 0 NACHT domain AAA_3 PF07726.11 KKK15294.1 - 0.037 13.9 0.0 0.44 10.4 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) KTI12 PF08433.10 KKK15294.1 - 0.046 13.2 0.0 4 6.8 0.0 2.4 2 0 0 2 2 2 0 Chromatin associated protein KTI12 AAA_11 PF13086.6 KKK15294.1 - 0.055 13.2 0.1 0.71 9.6 0.0 2.4 2 1 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.25 KKK15294.1 - 0.17 11.5 0.0 2.1 8.0 0.0 2.7 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Pkinase PF00069.25 KKK15295.1 - 4.6e-24 85.2 0.0 1.3e-23 83.8 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK15295.1 - 3.8e-12 46.0 0.0 8.8e-12 44.8 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KKK15295.1 - 2.6e-07 29.8 0.0 3.5e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Rtt106 PF08512.12 KKK15296.1 - 1.5e-31 108.6 0.3 4.6e-31 107.1 0.1 1.9 2 0 0 2 2 2 1 Histone chaperone Rttp106-like ZapC PF07126.12 KKK15296.1 - 0.012 15.1 1.2 1 8.9 0.3 2.2 2 0 0 2 2 2 0 Cell-division protein ZapC PH_18 PF18469.1 KKK15296.1 - 0.04 13.9 0.0 0.11 12.5 0.0 1.6 2 0 0 2 2 2 0 Pleckstrin homology domain Vfa1 PF08432.10 KKK15296.1 - 0.82 10.0 8.7 1.6 9.0 8.7 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Cwf_Cwc_15 PF04889.12 KKK15296.1 - 8.2 6.1 20.1 18 5.0 20.1 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein NPR3 PF03666.13 KKK15296.1 - 8.8 5.0 6.5 15 4.2 6.5 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 APH PF01636.23 KKK15298.1 - 4.3e-35 121.8 0.0 4.3e-33 115.2 0.0 2.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 KKK15298.1 - 7.8e-05 22.1 0.0 0.00013 21.4 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase RIO1 PF01163.22 KKK15298.1 - 0.002 17.8 0.0 0.18 11.4 0.0 2.5 2 1 0 2 2 2 1 RIO1 family Choline_kinase PF01633.20 KKK15298.1 - 0.0021 17.7 0.0 0.0036 16.9 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Fructosamin_kin PF03881.14 KKK15298.1 - 0.0058 15.9 0.0 3.1 6.9 0.0 2.6 2 1 0 2 2 2 2 Fructosamine kinase DUF1679 PF07914.11 KKK15298.1 - 0.035 13.0 0.0 1.1 8.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) Aa_trans PF01490.18 KKK15299.1 - 2.2e-70 237.5 18.8 2.6e-70 237.2 18.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 KKK15299.1 - 3e-05 23.3 4.3 3e-05 23.3 4.3 2.1 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family MerC PF03203.14 KKK15299.1 - 0.0039 17.6 0.8 0.0039 17.6 0.8 3.3 2 1 0 2 2 2 1 MerC mercury resistance protein Bmt2 PF11968.8 KKK15300.1 - 5e-94 314.2 0.0 6.2e-94 313.9 0.0 1.1 1 0 0 1 1 1 1 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 Methyltransf_23 PF13489.6 KKK15300.1 - 0.0071 16.2 0.0 0.013 15.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 KKK15300.1 - 0.032 14.1 0.0 1.7 8.4 0.0 2.1 2 0 0 2 2 2 0 Hypothetical methyltransferase CLTH PF10607.9 KKK15301.1 - 1.2e-36 125.8 0.0 2.2e-36 125.0 0.0 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 KKK15301.1 - 0.13 12.3 0.0 0.31 11.1 0.0 1.7 1 0 0 1 1 1 0 LisH DKCLD PF08068.12 KKK15302.1 - 3.2e-33 113.6 0.1 6.5e-32 109.4 0.1 2.6 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_C_2 PF16198.5 KKK15302.1 - 2.1e-23 82.2 0.7 3.7e-23 81.5 0.7 1.4 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain TruB_N PF01509.18 KKK15302.1 - 5e-23 82.1 0.2 1.8e-20 73.8 0.2 3.3 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.20 KKK15302.1 - 4.4e-21 74.6 1.2 8.3e-21 73.7 1.2 1.5 1 0 0 1 1 1 1 PUA domain DER1 PF04511.15 KKK15302.1 - 8.1e-13 48.7 2.6 5.7e-10 39.4 0.1 2.7 1 1 1 3 3 3 2 Der1-like family UPF0113 PF03657.13 KKK15302.1 - 0.0033 17.6 0.0 0.008 16.4 0.0 1.6 1 0 0 1 1 1 1 UPF0113 PUA domain AP3D1 PF06375.11 KKK15302.1 - 0.44 10.8 21.4 0.68 10.1 21.4 1.3 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 GtrA PF04138.14 KKK15302.1 - 0.49 10.6 3.0 0.51 10.6 0.1 2.4 2 1 0 2 2 2 0 GtrA-like protein Med19 PF10278.9 KKK15302.1 - 1.1 9.1 16.3 2.1 8.3 16.3 1.4 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 PDT PF00800.18 KKK15303.1 - 1.3e-63 214.1 0.1 2e-63 213.5 0.1 1.2 1 0 0 1 1 1 1 Prephenate dehydratase ACT PF01842.25 KKK15303.1 - 0.015 15.1 0.0 0.035 13.9 0.0 1.7 1 0 0 1 1 1 0 ACT domain eRF1_2 PF03464.15 KKK15304.1 - 2.2e-47 160.7 0.1 3.5e-47 160.0 0.1 1.3 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 KKK15304.1 - 1.9e-39 134.6 0.5 3.8e-39 133.7 0.5 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.15 KKK15304.1 - 4.6e-21 75.2 0.0 7.6e-21 74.5 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 baeRF_family10 PF18854.1 KKK15304.1 - 4.9e-10 39.8 0.0 8.8e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 acVLRF1 PF18859.1 KKK15304.1 - 2.9e-07 30.9 0.0 4.6e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor Ribosomal_L7Ae PF01248.26 KKK15304.1 - 0.12 12.1 0.0 0.28 10.9 0.0 1.6 1 0 0 1 1 1 0 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DUF3440 PF11922.8 KKK15304.1 - 0.13 12.0 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3440) Rad50_zn_hook PF04423.14 KKK15304.1 - 0.16 11.8 0.1 22 5.0 0.0 3.1 2 0 0 2 2 2 0 Rad50 zinc hook motif SMI1_KNR4 PF09346.10 KKK15305.1 - 2.1e-34 118.8 0.0 4.8e-34 117.6 0.0 1.6 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) SUKH_6 PF14568.6 KKK15305.1 - 0.12 12.8 0.0 1.5 9.2 0.0 2.2 1 1 0 1 1 1 0 SMI1-KNR4 cell-wall Thioredoxin PF00085.20 KKK15306.1 - 0.00014 21.8 0.0 0.00022 21.1 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin PGA2 PF07543.12 KKK15306.1 - 1.8 8.5 4.6 3.4 7.7 4.6 1.4 1 0 0 1 1 1 0 Protein trafficking PGA2 EamA PF00892.20 KKK15307.1 - 1.3e-05 25.4 6.4 1.3e-05 25.4 6.4 2.3 2 0 0 2 2 2 1 EamA-like transporter family UPF0370 PF13980.6 KKK15307.1 - 0.16 12.0 0.0 0.6 10.2 0.0 2.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0370) PHO4 PF01384.20 KKK15307.1 - 1.4 7.9 14.6 0.32 10.0 6.4 2.3 1 1 0 2 2 2 0 Phosphate transporter family DUF2431 PF10354.9 KKK15308.1 - 6.4e-60 202.2 0.0 1.7e-59 200.9 0.0 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF2431) TFIIA PF03153.13 KKK15308.1 - 0.0052 16.8 4.4 0.0079 16.2 4.4 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit RXT2_N PF08595.11 KKK15308.1 - 0.16 12.0 5.7 3.5 7.6 0.7 2.5 2 0 0 2 2 2 0 RXT2-like, N-terminal NOA36 PF06524.12 KKK15308.1 - 0.31 10.3 15.0 2 7.6 7.0 2.3 2 0 0 2 2 2 0 NOA36 protein TRAP_alpha PF03896.16 KKK15308.1 - 0.46 9.7 3.3 5 6.2 1.2 2.2 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit DUF4746 PF15928.5 KKK15308.1 - 0.53 9.7 4.6 1.5 8.1 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) FAM176 PF14851.6 KKK15308.1 - 1.4 8.6 9.5 1.9 8.2 0.3 2.7 3 0 0 3 3 3 0 FAM176 family dsrm PF00035.26 KKK15308.1 - 1.6 9.5 0.0 1.6 9.5 0.0 4.0 4 1 0 4 4 4 0 Double-stranded RNA binding motif TLP-20 PF06088.11 KKK15308.1 - 2.6 7.9 10.2 0.61 10.0 0.5 2.7 3 0 0 3 3 3 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Sigma70_ner PF04546.13 KKK15308.1 - 7 6.5 11.9 5.1 6.9 3.9 2.7 3 0 0 3 3 3 0 Sigma-70, non-essential region GHMP_kinases_N PF00288.26 KKK15309.1 - 4.5e-10 39.6 0.0 1e-09 38.5 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KKK15309.1 - 0.00021 21.6 0.0 0.00044 20.6 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal Ribosomal_L23eN PF03939.13 KKK15310.1 - 2.6e-27 94.8 8.9 5.3e-27 93.8 8.9 1.5 1 0 0 1 1 1 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.20 KKK15310.1 - 1.6e-15 57.2 1.4 2.7e-15 56.5 1.4 1.4 1 0 0 1 1 1 1 Ribosomal protein L23 PNRC PF15365.6 KKK15311.1 - 9.3e-09 34.9 7.7 9.3e-09 34.9 7.7 3.8 3 0 0 3 3 3 1 Proline-rich nuclear receptor coactivator motif zf-rbx1 PF12678.7 KKK15312.1 - 2.5e-19 69.3 8.7 3.7e-19 68.8 8.7 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KKK15312.1 - 5e-13 48.9 6.6 6.9e-13 48.5 6.6 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 KKK15312.1 - 4.5e-05 23.7 11.5 0.0013 19.0 11.5 2.2 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KKK15312.1 - 0.00026 20.8 5.2 0.0019 18.0 5.2 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KKK15312.1 - 0.00058 19.6 0.4 0.00058 19.6 0.4 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KKK15312.1 - 0.11 12.4 6.1 0.42 10.5 0.9 2.2 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KKK15312.1 - 0.22 11.6 4.8 0.53 10.4 4.8 1.7 1 1 0 1 1 1 0 RING-type zinc-finger Zn_ribbon_17 PF17120.5 KKK15312.1 - 1.7 8.3 9.5 67 3.2 9.5 2.2 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.5 KKK15312.1 - 2 8.2 12.7 1.8e+02 2.0 12.7 2.4 1 1 0 1 1 1 0 RING-like zinc finger CorA PF01544.18 KKK15313.1 - 1.1e-40 139.7 0.0 1.8e-40 139.1 0.0 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Spt20 PF12090.8 KKK15314.1 - 5.9e-63 212.6 1.5 5.9e-63 212.6 1.5 7.1 3 2 2 5 5 5 1 Spt20 family Shadoo PF14999.6 KKK15315.1 - 0.026 14.6 0.5 0.074 13.1 0.5 1.8 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective Hexapep PF00132.24 KKK15316.1 - 7.3e-10 38.2 5.2 0.00011 21.8 1.0 3.0 1 1 1 2 2 2 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 KKK15316.1 - 0.0016 18.9 0.0 0.0028 18.0 0.0 1.6 1 1 0 1 1 1 1 MobA-like NTP transferase domain Fucokinase PF07959.12 KKK15316.1 - 0.0026 16.8 1.9 0.0091 15.0 1.9 1.8 1 1 0 1 1 1 1 L-fucokinase DUF4954 PF16314.5 KKK15316.1 - 0.045 11.9 1.7 0.12 10.5 1.7 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4954) GTP_EFTU PF00009.27 KKK15316.1 - 0.12 11.9 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain NTP_transferase PF00483.23 KKK15316.1 - 0.19 11.3 0.0 0.3 10.6 0.0 1.2 1 0 0 1 1 1 0 Nucleotidyl transferase Hexapep_2 PF14602.6 KKK15316.1 - 1.7 8.4 6.8 1.5 8.7 1.4 2.9 2 2 0 2 2 2 0 Hexapeptide repeat of succinyl-transferase Uds1 PF15456.6 KKK15326.1 - 7.6e-42 142.6 4.7 7.6e-42 142.6 4.7 5.7 3 1 1 4 4 4 1 Up-regulated During Septation Rab5-bind PF09311.11 KKK15326.1 - 0.0044 16.5 13.0 0.0044 16.5 13.0 5.5 2 1 4 6 6 6 2 Rabaptin-like protein RsgA_GTPase PF03193.16 KKK15326.1 - 0.027 14.4 0.1 0.095 12.6 0.1 1.9 1 0 0 1 1 1 0 RsgA GTPase DUF4407 PF14362.6 KKK15326.1 - 0.078 12.3 54.3 0.64 9.3 13.4 4.6 2 1 3 5 5 5 0 Domain of unknown function (DUF4407) DUF826 PF05696.11 KKK15326.1 - 0.3 11.2 4.2 11 6.2 0.2 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF826) Bacillus_HBL PF05791.11 KKK15326.1 - 0.54 10.1 14.5 2.3 8.0 2.0 4.0 1 1 3 4 4 4 0 Bacillus haemolytic enterotoxin (HBL) DUF2388 PF09498.10 KKK15326.1 - 0.54 10.3 9.5 28 4.8 0.2 5.0 4 1 0 4 4 4 0 Protein of unknown function (DUF2388) MFS_1 PF07690.16 KKK15327.1 - 7.8e-12 44.8 15.8 8.7e-12 44.6 15.8 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Fungal_trans_2 PF11951.8 KKK15328.1 - 2e-06 26.9 0.3 2.6e-06 26.5 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK15328.1 - 0.0086 16.2 3.2 0.0086 16.2 3.2 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-piccolo PF05715.13 KKK15328.1 - 0.17 12.1 0.2 0.17 12.1 0.2 2.3 3 0 0 3 3 3 0 Piccolo Zn-finger ICMT PF04140.14 KKK15329.1 - 2.2e-09 37.6 4.3 1.5e-07 31.7 0.9 2.3 1 1 1 2 2 2 2 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 KKK15329.1 - 1.7e-06 28.4 3.4 4.2e-05 23.9 0.7 2.5 1 1 1 2 2 2 2 Phospholipid methyltransferase ERG4_ERG24 PF01222.17 KKK15329.1 - 0.031 13.0 0.3 0.047 12.5 0.3 1.3 1 0 0 1 1 1 0 Ergosterol biosynthesis ERG4/ERG24 family RTA1 PF04479.13 KKK15330.1 - 1.7e-58 197.7 4.4 2.2e-58 197.3 4.4 1.2 1 0 0 1 1 1 1 RTA1 like protein MFS_1 PF07690.16 KKK15331.1 - 2.4e-39 135.3 57.2 2.4e-39 135.3 57.2 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF5305 PF17231.2 KKK15331.1 - 0.2 11.0 0.1 0.54 9.6 0.1 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5305) Bys1 PF04681.12 KKK15332.1 - 1.8e-15 57.2 0.8 2.1e-15 57.0 0.8 1.0 1 0 0 1 1 1 1 Blastomyces yeast-phase-specific protein Aldo_ket_red PF00248.21 KKK15333.1 - 2.4e-42 145.1 0.0 3.3e-41 141.4 0.0 1.9 1 1 0 1 1 1 1 Aldo/keto reductase family Mrx7 PF10906.8 KKK15334.1 - 1.4e-13 50.9 0.0 1.8e-13 50.5 0.0 1.2 1 0 0 1 1 1 1 MIOREX complex component 7 Y_phosphatase PF00102.27 KKK15335.1 - 3.5e-51 174.0 0.0 1.1e-50 172.5 0.0 1.7 1 1 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 KKK15335.1 - 0.0041 17.2 0.0 0.012 15.7 0.0 1.8 2 0 0 2 2 2 1 Inositol hexakisphosphate DSPc PF00782.20 KKK15335.1 - 0.0086 15.9 0.1 0.027 14.3 0.1 1.8 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 KKK15335.1 - 0.035 14.1 0.0 0.076 13.0 0.0 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family Mid2 PF04478.12 KKK15336.1 - 3.2e-06 27.0 1.2 3.2e-06 27.0 1.2 3.3 1 1 2 3 3 3 1 Mid2 like cell wall stress sensor Presenilin PF01080.17 KKK15336.1 - 0.0022 16.8 3.8 0.003 16.4 3.8 1.3 1 0 0 1 1 1 1 Presenilin SOG2 PF10428.9 KKK15336.1 - 0.0091 15.3 26.8 0.011 15.0 26.8 1.3 1 0 0 1 1 1 1 RAM signalling pathway protein DUF5585 PF17823.1 KKK15336.1 - 0.039 12.9 55.5 0.045 12.7 55.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5585) Macoilin PF09726.9 KKK15336.1 - 0.06 11.9 12.6 0.076 11.6 12.6 1.2 1 0 0 1 1 1 0 Macoilin family Utp14 PF04615.13 KKK15336.1 - 0.21 10.1 7.5 0.23 10.0 7.5 1.1 1 0 0 1 1 1 0 Utp14 protein SLC12 PF03522.15 KKK15336.1 - 7.7 5.4 8.8 10 5.0 8.8 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Pex19 PF04614.12 KKK15338.1 - 3e-74 249.9 9.6 3.4e-74 249.7 9.6 1.0 1 0 0 1 1 1 1 Pex19 protein family T2SSF PF00482.23 KKK15338.1 - 0.15 12.0 1.6 4.3 7.3 0.1 3.1 3 1 0 3 3 3 0 Type II secretion system (T2SS), protein F GET2 PF08690.10 KKK15338.1 - 0.45 10.2 12.4 0.072 12.8 4.5 2.3 1 1 1 2 2 2 0 GET complex subunit GET2 DNA_pol_phi PF04931.13 KKK15338.1 - 1 7.3 4.3 1.3 7.0 4.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi WD40 PF00400.32 KKK15339.1 - 4.7e-50 166.5 17.9 7.2e-08 33.0 0.0 8.5 8 0 0 8 8 8 6 WD domain, G-beta repeat F-box-like PF12937.7 KKK15339.1 - 2.3e-14 53.0 0.7 5.4e-14 51.8 0.7 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KKK15339.1 - 9.1e-12 44.5 1.4 5.7e-11 42.0 0.3 2.4 1 1 1 2 2 2 1 F-box domain Nup160 PF11715.8 KKK15339.1 - 2.1e-09 36.6 8.3 0.022 13.4 0.7 5.8 4 1 2 6 6 6 4 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 KKK15339.1 - 8.4e-07 29.2 0.0 0.02 15.2 0.0 4.8 3 1 3 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain F-box_4 PF15966.5 KKK15339.1 - 0.00082 19.2 0.6 0.0036 17.2 0.0 2.3 2 1 1 3 3 3 1 F-box PRANC PF09372.10 KKK15339.1 - 0.13 12.6 0.0 0.24 11.8 0.0 1.4 1 0 0 1 1 1 0 PRANC domain Hydrolase PF00702.26 KKK15341.1 - 5.6e-09 36.6 0.0 2.2e-08 34.7 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KKK15341.1 - 2.3e-08 34.4 0.0 2.9e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KKK15341.1 - 0.012 15.7 0.0 0.021 14.9 0.0 1.4 1 0 0 1 1 1 0 HAD-hyrolase-like DUF4437 PF14499.6 KKK15341.1 - 0.016 14.4 0.0 0.024 13.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4437) 5_nucleotid PF05761.14 KKK15341.1 - 0.032 13.1 0.1 0.17 10.8 0.0 1.9 1 1 1 2 2 2 0 5' nucleotidase family HAD PF12710.7 KKK15341.1 - 0.12 12.7 0.0 0.16 12.4 0.0 1.2 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase APG17 PF04108.12 KKK15342.1 - 1.8e-137 458.7 0.1 2.1e-137 458.4 0.1 1.0 1 0 0 1 1 1 1 Autophagy protein Apg17 RasGAP_C PF03836.15 KKK15342.1 - 0.23 11.6 3.5 18 5.5 0.1 3.8 3 1 1 4 4 4 0 RasGAP C-terminus Macro_2 PF14519.6 KKK15343.1 - 0.0055 16.1 0.0 0.0069 15.8 0.0 1.3 1 0 0 1 1 1 1 Macro-like domain Curto_V3 PF07436.11 KKK15343.1 - 0.084 13.3 0.0 0.13 12.7 0.0 1.2 1 0 0 1 1 1 0 Curtovirus V3 protein TB2_DP1_HVA22 PF03134.19 KKK15344.1 - 1.2e-27 95.7 7.8 2.1e-27 94.9 7.8 1.4 1 0 0 1 1 1 1 TB2/DP1, HVA22 family DUF1614 PF07758.11 KKK15344.1 - 0.028 14.4 0.3 0.033 14.2 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1614) Acid_PPase PF12689.7 KKK15362.1 - 5.2e-71 237.9 0.0 6.1e-71 237.7 0.0 1.0 1 0 0 1 1 1 1 Acid Phosphatase Fungal_trans_2 PF11951.8 KKK15363.1 - 1.6e-46 158.8 0.0 2.3e-46 158.3 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK15363.1 - 3e-08 33.6 10.8 6.5e-08 32.6 10.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 KKK15365.1 - 2.1e-25 89.4 39.9 2.1e-25 89.4 39.9 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KKK15365.1 - 1.4e-08 34.1 25.9 2.8e-08 33.1 25.9 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter P5CR_dimer PF14748.6 KKK15365.1 - 0.076 13.3 0.0 0.15 12.4 0.0 1.5 1 0 0 1 1 1 0 Pyrroline-5-carboxylate reductase dimerisation TRI12 PF06609.13 KKK15365.1 - 0.077 11.4 11.5 0.0054 15.2 5.5 1.8 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) Fungal_trans PF04082.18 KKK15366.1 - 3.5e-19 68.9 4.6 5.3e-19 68.3 4.6 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.6 KKK15366.1 - 7.1e-07 29.4 14.9 7.6e-05 23.0 5.5 3.0 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.26 KKK15366.1 - 0.016 15.6 19.3 0.039 14.4 5.3 3.4 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_3rep PF18868.1 KKK15366.1 - 0.04 14.6 0.7 3 8.5 0.1 2.5 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_4 PF13894.6 KKK15366.1 - 0.21 12.5 19.6 0.26 12.2 4.1 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger Zn-ribbon_8 PF09723.10 KKK15366.1 - 1.4 9.1 3.7 5.8 7.1 3.7 2.1 1 0 0 1 1 1 0 Zinc ribbon domain zf-C2H2_jaz PF12171.8 KKK15366.1 - 3.1 8.2 7.4 1.3 9.3 3.7 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Zn_clus PF00172.18 KKK15367.1 - 0.0019 18.3 12.2 0.0037 17.4 12.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RNA_pol_Rpc4 PF05132.14 KKK15368.1 - 1.5e-32 113.1 0.0 1.5e-32 113.1 0.0 5.2 3 2 2 5 5 5 1 RNA polymerase III RPC4 PBP1_TM PF14812.6 KKK15368.1 - 0.026 14.9 8.5 0.026 14.9 8.5 4.4 3 1 1 5 5 5 0 Transmembrane domain of transglycosylase PBP1 at N-terminal TMEM100 PF16311.5 KKK15369.1 - 0.029 14.0 0.0 0.044 13.4 0.0 1.3 1 0 0 1 1 1 0 Transmembrane protein 100 UPRTase PF14681.6 KKK15370.1 - 6.5e-72 241.3 0.0 7.4e-72 241.1 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 KKK15370.1 - 3.3e-05 23.4 0.0 5.3e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain CRCB PF02537.15 KKK15371.1 - 1.5e-38 131.0 11.9 1.4e-22 79.8 8.0 2.3 2 0 0 2 2 2 2 CrcB-like protein, Camphor Resistance (CrcB) Cyclin_N PF00134.23 KKK15372.1 - 3.8e-45 152.7 0.2 8.1e-45 151.7 0.2 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KKK15372.1 - 2e-31 108.5 0.3 6.4e-31 106.9 0.1 2.0 2 0 0 2 2 2 1 Cyclin, C-terminal domain Glyco_hydro_92 PF07971.12 KKK15373.1 - 9.5e-148 492.9 0.0 1.1e-147 492.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 KKK15373.1 - 1.6e-59 201.7 0.5 2.3e-59 201.2 0.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain Gln-synt_N PF03951.19 KKK15373.1 - 0.086 12.6 0.1 0.2 11.4 0.1 1.5 1 0 0 1 1 1 0 Glutamine synthetase, beta-Grasp domain 4HBT PF03061.22 KKK15374.1 - 1.9e-13 50.6 0.0 3.4e-13 49.7 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily Aminotran_5 PF00266.19 KKK15375.1 - 6.1e-21 74.8 0.0 5.5e-14 51.9 0.0 3.1 1 1 1 2 2 2 2 Aminotransferase class-V CDC24 PF06395.11 KKK15383.1 - 2.7e-31 107.7 0.0 7.9e-31 106.2 0.0 1.8 2 0 0 2 2 2 1 CDC24 Calponin RhoGEF PF00621.20 KKK15383.1 - 3.2e-28 99.2 0.7 5.2e-28 98.5 0.7 1.3 1 0 0 1 1 1 1 RhoGEF domain DUF4404 PF14357.6 KKK15383.1 - 0.97 10.1 5.0 3.3 8.4 0.5 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) WD40 PF00400.32 KKK15384.1 - 1.4e-28 98.5 12.9 0.00014 22.5 0.0 7.8 8 0 0 8 8 8 5 WD domain, G-beta repeat F-box-like PF12937.7 KKK15384.1 - 5.5e-13 48.6 0.4 1.6e-12 47.1 0.4 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KKK15384.1 - 7e-08 32.2 0.3 1.6e-07 31.0 0.3 1.7 1 0 0 1 1 1 1 F-box domain ANAPC4_WD40 PF12894.7 KKK15384.1 - 3.6e-05 24.0 0.5 0.86 9.9 0.0 3.8 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KKK15384.1 - 0.0007 18.4 1.1 0.46 9.1 0.4 2.7 2 1 0 2 2 2 2 Nucleoporin Nup120/160 BBS2_Mid PF14783.6 KKK15384.1 - 0.039 14.0 0.1 53 3.9 0.0 4.9 5 2 1 6 6 6 0 Ciliary BBSome complex subunit 2, middle region Peptidase_M48 PF01435.18 KKK15384.1 - 0.11 12.2 0.1 0.23 11.2 0.1 1.4 1 0 0 1 1 1 0 Peptidase family M48 MID_MedPIWI PF18296.1 KKK15384.1 - 0.14 11.9 5.0 0.58 9.9 3.9 2.0 2 0 0 2 2 2 0 MID domain of medPIWI Tmemb_14 PF03647.13 KKK15385.1 - 1.9e-20 73.4 9.1 2.7e-20 72.9 9.1 1.2 1 0 0 1 1 1 1 Transmembrane proteins 14C MFS_1 PF07690.16 KKK15386.1 - 3.7e-30 105.1 36.6 1.2e-29 103.4 14.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KKK15386.1 - 6.3e-09 35.2 5.2 6.3e-09 35.2 5.2 3.1 2 2 1 3 3 3 1 Sugar (and other) transporter TFR_dimer PF04253.15 KKK15387.1 - 7.4e-31 106.8 0.0 1.2e-30 106.1 0.0 1.3 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 KKK15387.1 - 1.3e-18 67.4 0.0 2.1e-18 66.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 KKK15387.1 - 1e-10 41.5 0.2 3.1e-10 40.0 0.0 1.8 2 0 0 2 2 2 1 PA domain CMD PF02627.20 KKK15387.1 - 6.4e-05 22.9 0.0 0.00021 21.3 0.0 1.9 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family Nicastrin PF05450.15 KKK15387.1 - 0.0072 15.8 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 Nicastrin DUF5427 PF10310.9 KKK15388.1 - 2.8e-163 544.2 0.1 3.5e-163 543.9 0.1 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5427) Flu_M1_C PF08289.11 KKK15388.1 - 0.021 15.0 3.1 0.22 11.8 1.3 2.5 2 0 0 2 2 2 0 Influenza Matrix protein (M1) C-terminal domain SARAF PF06682.12 KKK15388.1 - 1.4 8.5 5.3 2.2 7.8 5.3 1.3 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis SurE PF01975.17 KKK15389.1 - 3e-50 170.7 0.0 4e-50 170.3 0.0 1.2 1 0 0 1 1 1 1 Survival protein SurE Zn_clus PF00172.18 KKK15390.1 - 0.0018 18.4 10.2 0.0036 17.4 10.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NUC153 PF08159.12 KKK15390.1 - 0.16 11.8 2.9 1.8 8.4 0.2 2.6 2 0 0 2 2 2 0 NUC153 domain zf-C2H2_4 PF13894.6 KKK15391.1 - 1e-06 29.1 2.1 0.013 16.3 0.1 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KKK15391.1 - 0.00022 21.5 2.8 0.011 16.2 0.1 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type HDV_ag PF01517.18 KKK15391.1 - 0.013 15.3 0.1 0.037 13.8 0.1 1.7 1 0 0 1 1 1 0 Hepatitis delta virus delta antigen zf-C2H2_11 PF16622.5 KKK15391.1 - 0.12 12.2 1.4 0.25 11.2 1.4 1.5 1 0 0 1 1 1 0 zinc-finger C2H2-type Ima1_N PF09779.9 KKK15391.1 - 0.13 13.1 0.5 0.28 12.0 0.1 1.8 2 0 0 2 2 2 0 Ima1 N-terminal domain Methyltransf_31 PF13847.6 KKK15393.1 - 2.6e-13 50.1 0.0 4.3e-12 46.1 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KKK15393.1 - 3.3e-08 33.5 0.0 5.9e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKK15393.1 - 3.8e-07 30.7 0.0 3.4e-06 27.7 0.0 2.2 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KKK15393.1 - 2e-05 25.1 0.1 0.0002 21.9 0.1 2.4 1 1 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 KKK15393.1 - 0.0011 18.7 0.1 0.002 17.7 0.1 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Herpes_UL32 PF06070.11 KKK15393.1 - 0.0031 15.4 2.9 0.64 7.7 0.0 2.0 2 0 0 2 2 2 2 Herpesvirus large structural phosphoprotein UL32 Methyltransf_12 PF08242.12 KKK15393.1 - 0.0081 16.9 0.0 0.023 15.4 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KKK15393.1 - 0.05 13.1 0.0 0.085 12.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_32 PF13679.6 KKK15393.1 - 0.12 12.4 0.1 0.24 11.4 0.0 1.5 2 0 0 2 2 2 0 Methyltransferase domain PCMT PF01135.19 KKK15393.1 - 0.13 12.0 0.0 0.2 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PBP1_TM PF14812.6 KKK15393.1 - 7.3 7.0 10.1 8.3 6.9 4.6 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Ribosomal_S9 PF00380.19 KKK15394.1 - 2.1e-40 138.0 0.3 3.4e-40 137.3 0.3 1.3 1 0 0 1 1 1 1 Ribosomal protein S9/S16 EF1G PF00647.19 KKK15395.1 - 2.9e-43 146.3 0.1 5e-43 145.5 0.1 1.4 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.25 KKK15395.1 - 2.5e-14 53.2 0.0 7.4e-14 51.7 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KKK15395.1 - 3.2e-11 43.4 0.0 9.5e-11 41.9 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KKK15395.1 - 9.8e-09 35.1 0.3 6.5e-08 32.5 0.0 2.4 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KKK15395.1 - 3.3e-06 27.2 0.0 9.2e-06 25.8 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KKK15395.1 - 0.0066 16.8 0.0 0.015 15.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain OAD_gamma PF04277.13 KKK15395.1 - 1.1 9.9 5.1 2.6 8.7 5.1 1.6 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain PP2C PF00481.21 KKK15396.1 - 5e-52 177.1 0.0 8.1e-52 176.4 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_8 PF13855.6 KKK15396.1 - 8.8e-30 102.3 61.6 2.3e-06 27.2 1.2 10.5 7 4 4 11 11 11 9 Leucine rich repeat Guanylate_cyc PF00211.20 KKK15396.1 - 2.4e-28 99.0 0.0 5e-28 98.0 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain LRR_4 PF12799.7 KKK15396.1 - 6.6e-25 86.8 58.2 0.00039 20.8 1.3 12.4 10 1 3 13 13 13 10 Leucine Rich repeats (2 copies) Ad_cyc_g-alpha PF08509.11 KKK15396.1 - 3.8e-08 32.9 0.0 1.5e-07 31.0 0.0 2.0 1 0 0 1 1 1 1 Adenylate cyclase G-alpha binding domain LRR_9 PF14580.6 KKK15396.1 - 6.6e-08 32.3 17.6 0.0048 16.4 0.1 4.8 2 1 3 5 5 5 4 Leucine-rich repeat LRR_5 PF13306.6 KKK15396.1 - 0.0092 15.9 5.4 2.9 7.9 0.0 4.7 5 1 0 5 5 5 1 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 KKK15396.1 - 0.27 11.9 55.1 3.8 8.4 0.1 13.6 14 2 1 15 15 15 0 Leucine Rich Repeat Zn_clus PF00172.18 KKK15397.1 - 3.7e-07 30.1 9.3 5.5e-07 29.6 9.3 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MSC PF09402.10 KKK15398.1 - 6.4e-107 357.9 0.0 9e-107 357.4 0.0 1.2 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain HeH PF12949.7 KKK15398.1 - 4.5e-17 61.5 0.2 7.7e-17 60.7 0.2 1.4 1 0 0 1 1 1 1 HeH/LEM domain APH PF01636.23 KKK15399.1 - 0.00019 21.5 0.1 0.00072 19.6 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family MOZ_SAS PF01853.18 KKK15400.1 - 8.4e-63 211.3 0.0 1.5e-62 210.5 0.0 1.4 1 1 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 KKK15400.1 - 8.2e-18 63.8 0.5 1.5e-17 62.9 0.5 1.5 1 0 0 1 1 1 1 MYST family zinc finger domain Inhibitor_I10 PF12559.8 KKK15400.1 - 0.0026 18.0 0.0 0.0057 16.9 0.0 1.5 1 0 0 1 1 1 1 Serine endopeptidase inhibitors Cpn60_TCP1 PF00118.24 KKK15401.1 - 2e-163 544.5 0.1 2.3e-163 544.4 0.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family tRNA-synt_2 PF00152.20 KKK15402.1 - 1.6e-69 234.4 0.0 3.8e-69 233.2 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) RRM_1 PF00076.22 KKK15402.1 - 1.6e-11 43.8 0.0 2.9e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) tRNA_anti-codon PF01336.25 KKK15402.1 - 2.3e-05 24.3 0.0 4e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Nop PF01798.18 KKK15404.1 - 1.9e-88 295.8 0.1 1.9e-88 295.8 0.1 1.7 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 KKK15404.1 - 2.8e-19 69.2 0.1 1.5e-18 66.9 0.1 2.4 1 0 0 1 1 1 1 NOP5NT (NUC127) domain HBM PF16591.5 KKK15404.1 - 0.0011 18.4 0.3 0.022 14.2 0.0 2.6 3 0 0 3 3 3 1 Helical bimodular sensor domain RNA_polI_A34 PF08208.11 KKK15404.1 - 1 9.4 36.7 2.1 8.4 36.7 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 YL1 PF05764.13 KKK15404.1 - 1.3 9.1 26.7 2 8.5 26.7 1.3 1 0 0 1 1 1 0 YL1 nuclear protein CobT PF06213.12 KKK15404.1 - 4.1 6.7 21.5 1.6 8.0 18.5 1.9 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT DUF1682 PF07946.14 KKK15404.1 - 4.5 6.4 23.2 21 4.2 0.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1682) DUF1744 PF08490.12 KKK15405.1 - 2.3e-153 510.6 0.0 3.2e-153 510.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.19 KKK15405.1 - 1.7e-85 287.2 0.6 7.6e-85 285.0 0.4 2.1 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.21 KKK15405.1 - 2e-15 56.5 0.0 1.3e-12 47.2 0.0 2.8 2 1 0 2 2 2 2 DNA polymerase family B DNA_pol_B_exo2 PF10108.9 KKK15405.1 - 2.2e-08 34.0 0.1 5.9e-08 32.7 0.1 1.6 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 KKK15405.1 - 5e-05 23.3 0.0 0.0002 21.4 0.0 2.0 1 0 0 1 1 1 1 RNase_H superfamily DUF3767 PF12597.8 KKK15406.1 - 4.8e-35 119.4 0.2 7.9e-35 118.7 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3767) FAM153 PF15722.5 KKK15406.1 - 3.9 7.8 6.9 15 6.0 0.2 3.0 3 0 0 3 3 3 0 FAM153 family Utp8 PF10395.9 KKK15410.1 - 2.3e-12 46.3 0.0 1.4e-10 40.4 0.0 3.2 2 1 0 2 2 2 1 Utp8 family PX PF00787.24 KKK15411.1 - 2e-17 63.2 0.4 5e-17 61.9 0.4 1.7 1 0 0 1 1 1 1 PX domain AAA PF00004.29 KKK15411.1 - 4.4e-09 36.9 0.0 2e-08 34.7 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 KKK15411.1 - 1.1e-05 25.5 0.1 0.0011 18.9 0.0 3.1 3 0 0 3 3 3 1 Rad17 P-loop domain AAA_16 PF13191.6 KKK15411.1 - 1.9e-05 25.2 0.0 4.8e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KKK15411.1 - 3.5e-05 24.1 0.3 0.00013 22.2 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KKK15411.1 - 0.00024 21.7 0.1 0.0009 19.8 0.0 2.1 2 0 0 2 2 1 1 AAA domain RuvB_N PF05496.12 KKK15411.1 - 0.008 15.9 0.0 0.016 15.0 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Tmemb_cc2 PF10267.9 KKK15411.1 - 0.021 14.0 1.1 0.043 13.0 1.1 1.4 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein AAA_5 PF07728.14 KKK15411.1 - 0.025 14.6 0.0 0.086 12.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) TIP49 PF06068.13 KKK15411.1 - 0.037 13.2 0.0 0.073 12.3 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_7 PF12775.7 KKK15411.1 - 0.047 13.2 0.0 0.097 12.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF815 PF05673.13 KKK15411.1 - 0.13 11.4 0.0 0.29 10.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) T2SSE PF00437.20 KKK15411.1 - 0.14 11.2 0.0 0.26 10.3 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Prefoldin_3 PF13758.6 KKK15411.1 - 0.41 10.7 3.5 0.31 11.1 0.1 2.6 3 0 0 3 3 3 0 Prefoldin subunit AAA_11 PF13086.6 KKK15411.1 - 0.78 9.5 4.2 18 5.0 0.0 3.4 4 0 0 4 4 4 0 AAA domain zf-C2H2 PF00096.26 KKK15412.1 - 1.1e-08 35.1 12.4 0.00038 20.7 0.6 3.9 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KKK15412.1 - 2e-07 31.1 0.7 2e-07 31.1 0.7 3.7 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KKK15412.1 - 0.0011 19.7 4.7 0.028 15.2 0.3 4.4 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_8 PF15909.5 KKK15412.1 - 0.004 17.4 2.9 0.027 14.8 0.9 2.4 1 1 1 2 2 2 1 C2H2-type zinc ribbon zf-met PF12874.7 KKK15412.1 - 0.0091 16.4 6.2 0.043 14.2 0.9 2.8 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-LYAR PF08790.11 KKK15412.1 - 0.017 15.0 4.9 1.6 8.7 0.3 3.4 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger zf-C2H2_aberr PF17017.5 KKK15412.1 - 1.9 8.6 10.0 0.45 10.7 0.3 2.8 3 0 0 3 3 3 0 Aberrant zinc-finger LysM PF01476.20 KKK15413.1 - 5.2e-05 23.2 0.2 0.00022 21.2 0.0 2.1 2 0 0 2 2 2 1 LysM domain RIFIN PF02009.16 KKK15413.1 - 0.33 10.8 4.3 0.52 10.1 4.3 1.3 1 0 0 1 1 1 0 Rifin SOG2 PF10428.9 KKK15413.1 - 0.57 9.3 20.1 0.73 9.0 20.1 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein GREB1 PF15782.5 KKK15413.1 - 4.5 4.3 10.2 5.8 3.9 10.2 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SAP130_C PF16014.5 KKK15413.1 - 9.7 5.2 17.2 16 4.4 17.2 1.5 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP130 C-terminus Fungal_trans PF04082.18 KKK15414.1 - 1.2e-26 93.4 1.7 1.7e-26 92.8 1.7 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK15414.1 - 2.7e-08 33.8 12.1 5.6e-08 32.8 12.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Tautomerase_3 PF14832.6 KKK15415.1 - 3.9e-50 169.6 0.1 4.4e-50 169.5 0.1 1.0 1 0 0 1 1 1 1 Putative oxalocrotonate tautomerase enzyme Epimerase PF01370.21 KKK15416.1 - 9.6e-15 54.7 0.0 2e-14 53.6 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KKK15416.1 - 4e-11 42.5 0.0 8.7e-11 41.3 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KKK15416.1 - 5.6e-08 32.9 0.0 1.4e-07 31.6 0.0 1.6 2 0 0 2 2 2 1 NAD(P)H-binding NAD_binding_4 PF07993.12 KKK15416.1 - 2.4e-06 26.9 0.0 0.0034 16.6 0.0 2.4 3 0 0 3 3 3 2 Male sterility protein GDP_Man_Dehyd PF16363.5 KKK15416.1 - 2.7e-06 27.0 0.0 1.1e-05 25.1 0.0 1.9 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 KKK15416.1 - 6.8e-05 22.2 0.0 0.00014 21.1 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.13 KKK15416.1 - 0.0034 17.0 0.0 0.024 14.2 0.0 2.0 2 0 0 2 2 2 1 NmrA-like family adh_short PF00106.25 KKK15416.1 - 0.0053 16.2 0.0 0.023 14.2 0.0 2.0 3 0 0 3 3 3 1 short chain dehydrogenase KR PF08659.10 KKK15416.1 - 0.024 14.6 0.0 5.1 7.0 0.0 2.2 2 0 0 2 2 2 0 KR domain ECH_1 PF00378.20 KKK15417.1 - 3.3e-44 151.1 0.0 5.1e-44 150.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase HMGL-like PF00682.19 KKK15417.1 - 3.8e-43 148.0 0.0 5.4e-43 147.4 0.0 1.2 1 0 0 1 1 1 1 HMGL-like ECH_2 PF16113.5 KKK15417.1 - 3.8e-26 92.4 0.0 6e-26 91.7 0.0 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase DUF1612 PF07756.12 KKK15417.1 - 0.11 12.8 0.1 1.1 9.6 0.5 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1612) AMP-binding PF00501.28 KKK15418.1 - 1.3e-82 277.7 0.0 1.9e-82 277.1 0.0 1.3 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KKK15418.1 - 5.3e-12 46.5 0.0 1.6e-11 45.0 0.0 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Zn_clus PF00172.18 KKK15419.1 - 3.7e-08 33.3 12.1 6.2e-08 32.6 12.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KKK15419.1 - 0.00053 18.9 0.1 0.11 11.3 0.0 2.6 2 1 0 2 2 2 2 Fungal specific transcription factor domain Acyl-CoA_dh_1 PF00441.24 KKK15420.1 - 1.9e-29 102.8 2.5 2.7e-29 102.3 2.5 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KKK15420.1 - 1e-23 84.2 0.0 4.7e-23 82.0 0.0 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KKK15420.1 - 8.1e-22 77.2 0.1 1.4e-21 76.5 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KKK15420.1 - 0.00015 22.1 1.0 0.00022 21.5 1.0 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain ATP-sulfurylase PF01747.17 KKK15420.1 - 0.15 11.5 0.2 0.77 9.2 0.0 2.0 2 0 0 2 2 2 0 ATP-sulfurylase Carboxyl_trans PF01039.22 KKK15421.1 - 2.6e-110 369.4 0.0 3.3e-110 369.0 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.17 KKK15422.1 - 1.9e-70 236.7 0.0 3.1e-70 235.9 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 KKK15422.1 - 1.2e-34 119.2 0.4 4e-23 82.1 0.0 2.6 2 0 0 2 2 2 2 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 KKK15422.1 - 6.3e-30 103.5 0.0 1.5e-29 102.3 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 KKK15422.1 - 4.3e-12 45.7 2.3 8.8e-12 44.7 2.3 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp PF02222.22 KKK15422.1 - 2.7e-09 36.8 0.0 6.3e-09 35.6 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 KKK15422.1 - 2.4e-08 33.8 0.0 5.1e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.14 KKK15422.1 - 4.4e-05 23.6 0.0 7.4e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_YheCD PF14398.6 KKK15422.1 - 0.015 14.5 0.0 2.1 7.5 0.0 2.3 2 0 0 2 2 2 0 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 KKK15422.1 - 0.018 14.3 0.0 0.088 12.0 0.0 1.9 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp Biotin_lipoyl_2 PF13533.6 KKK15422.1 - 0.04 13.7 0.0 0.15 11.9 0.0 2.0 2 0 0 2 2 2 0 Biotin-lipoyl like GCV_H PF01597.19 KKK15422.1 - 0.084 12.8 0.0 0.28 11.1 0.2 1.8 2 0 0 2 2 2 0 Glycine cleavage H-protein DUF3182 PF11379.8 KKK15422.1 - 0.11 11.4 0.0 0.21 10.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3182) ATP-grasp_4 PF13535.6 KKK15422.1 - 0.12 12.0 0.0 0.26 10.9 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp domain PHD PF00628.29 KKK15423.1 - 5.3e-08 32.6 9.3 5.3e-08 32.6 9.3 1.6 2 0 0 2 2 2 1 PHD-finger Zf_RING PF16744.5 KKK15423.1 - 0.016 15.3 5.9 0.032 14.3 5.9 1.5 1 0 0 1 1 1 0 KIAA1045 RING finger Shugoshin_N PF07558.11 KKK15423.1 - 0.029 14.2 0.4 0.049 13.5 0.4 1.3 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region DivIC PF04977.15 KKK15423.1 - 0.075 12.8 0.3 0.12 12.2 0.3 1.2 1 0 0 1 1 1 0 Septum formation initiator YabA PF06156.13 KKK15423.1 - 0.08 13.6 0.1 0.13 12.9 0.1 1.3 1 0 0 1 1 1 0 Initiation control protein YabA Cep57_CLD_2 PF14197.6 KKK15423.1 - 0.081 13.0 0.4 0.13 12.3 0.4 1.2 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 CASP_C PF08172.12 KKK15423.1 - 0.12 11.7 0.1 0.25 10.7 0.1 1.4 1 0 0 1 1 1 0 CASP C terminal zf-HC5HC2H PF13771.6 KKK15423.1 - 0.17 12.1 4.1 0.36 11.1 4.1 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain zf-RING_2 PF13639.6 KKK15423.1 - 3.3 8.1 15.5 0.39 11.1 11.3 1.7 2 0 0 2 2 2 0 Ring finger domain Peptidase_S10 PF00450.22 KKK15424.1 - 2.3e-94 317.2 0.1 2.9e-94 316.9 0.1 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase YXWGXW PF12779.7 KKK15424.1 - 0.017 15.3 0.8 0.043 14.0 0.8 1.7 1 0 0 1 1 1 0 YXWGXW repeat (2 copies) Glyco_hydro_92 PF07971.12 KKK15425.1 - 4.7e-149 497.2 0.1 5.8e-149 496.9 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 KKK15425.1 - 1e-60 205.6 3.9 1.9e-60 204.7 3.9 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain AA_permease_2 PF13520.6 KKK15426.1 - 5.9e-54 183.5 40.4 7.1e-54 183.2 40.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KKK15426.1 - 5.1e-19 68.2 27.1 5.1e-19 68.2 27.1 2.1 2 0 0 2 2 2 1 Amino acid permease Glyco_hydro_76 PF03663.14 KKK15427.1 - 2.3e-129 432.1 24.0 1.8e-122 409.4 22.1 2.0 1 1 1 2 2 2 2 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 KKK15427.1 - 0.013 14.6 12.1 0.11 11.6 1.9 2.9 1 1 1 2 2 2 0 Glycosyl Hydrolase Family 88 Kdo PF06293.14 KKK15428.1 - 8.5e-06 25.3 0.0 8.5e-06 25.3 0.0 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KKK15428.1 - 0.0027 17.7 0.1 0.0027 17.7 0.1 2.8 2 1 0 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.25 KKK15428.1 - 0.0031 16.9 0.0 0.0068 15.8 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Choline_kinase PF01633.20 KKK15428.1 - 0.019 14.6 0.1 0.019 14.6 0.1 1.7 2 0 0 2 2 2 0 Choline/ethanolamine kinase DUF2353 PF09789.9 KKK15428.1 - 0.085 12.2 15.3 0.14 11.5 15.3 1.2 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) Synaptobrevin PF00957.21 KKK15428.1 - 0.14 12.0 1.9 0.3 10.9 1.9 1.6 1 0 0 1 1 1 0 Synaptobrevin HSP70 PF00012.20 KKK15428.1 - 3.7 5.6 12.5 5.4 5.1 12.5 1.1 1 0 0 1 1 1 0 Hsp70 protein P22_portal PF16510.5 KKK15428.1 - 4.5 5.8 6.3 6.6 5.2 6.3 1.1 1 0 0 1 1 1 0 Phage P22-like portal protein EMP24_GP25L PF01105.24 KKK15428.1 - 6.4 6.7 5.9 14 5.6 5.9 1.5 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD adh_short_C2 PF13561.6 KKK15447.1 - 3.9e-47 160.8 0.0 1.1e-45 156.0 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KKK15447.1 - 8e-32 110.3 0.0 5.7e-31 107.5 0.0 1.9 1 1 1 2 2 2 1 short chain dehydrogenase KR PF08659.10 KKK15447.1 - 0.0032 17.4 0.0 0.054 13.4 0.0 2.2 1 1 0 1 1 1 1 KR domain DUF3535 PF12054.8 KKK15448.1 - 4e-125 418.5 0.0 4.1e-124 415.2 0.0 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF3535) SNF2_N PF00176.23 KKK15448.1 - 2.9e-62 210.4 0.0 6.5e-62 209.3 0.0 1.5 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KKK15448.1 - 1.2e-19 70.7 0.0 3e-19 69.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HEAT PF02985.22 KKK15448.1 - 1.6e-15 55.9 15.9 0.13 12.6 0.0 11.1 14 0 0 14 14 12 5 HEAT repeat HEAT_2 PF13646.6 KKK15448.1 - 2.7e-07 30.9 9.2 0.00071 19.9 0.1 6.6 6 1 0 7 7 7 1 HEAT repeats Vac14_Fab1_bd PF12755.7 KKK15448.1 - 4.8e-07 30.3 0.1 0.038 14.6 0.0 4.0 3 1 1 4 4 4 2 Vacuolar 14 Fab1-binding region TAF6_C PF07571.13 KKK15448.1 - 3.2e-05 24.2 0.0 0.84 10.0 0.0 5.5 6 0 0 6 6 6 1 TAF6 C-terminal HEAT repeat domain Cnd1 PF12717.7 KKK15448.1 - 0.00011 22.3 0.2 0.33 11.0 0.0 4.9 5 0 0 5 5 5 1 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 KKK15448.1 - 0.061 12.9 0.1 13 5.3 0.0 3.6 2 1 1 3 3 3 0 CLASP N terminal HEAT_EZ PF13513.6 KKK15448.1 - 0.36 11.4 17.6 29 5.3 0.3 7.6 8 0 0 8 8 8 0 HEAT-like repeat U3_snoRNA_assoc PF08297.11 KKK15448.1 - 3.3 8.5 5.5 0.98 10.2 0.6 2.7 2 0 0 2 2 2 0 U3 snoRNA associated HEAT_PBS PF03130.16 KKK15448.1 - 9.8 7.2 7.3 76 4.4 0.0 5.2 5 0 0 5 5 4 0 PBS lyase HEAT-like repeat DUF533 PF04391.12 KKK15449.1 - 0.043 13.4 0.2 1.9 8.0 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF533) Kelch_3 PF13415.6 KKK15450.1 - 9e-07 29.0 5.5 0.007 16.6 0.4 5.2 4 1 0 4 4 4 2 Galactose oxidase, central domain Kelch_4 PF13418.6 KKK15450.1 - 8.6e-06 25.7 2.6 0.0025 17.8 0.0 4.4 4 1 0 4 4 4 1 Galactose oxidase, central domain Kelch_6 PF13964.6 KKK15450.1 - 4.1e-05 23.7 6.2 1.4 9.3 0.0 4.9 5 0 0 5 5 5 2 Kelch motif TMEM154 PF15102.6 KKK15450.1 - 0.00015 21.7 0.0 0.00061 19.7 0.0 2.0 1 0 0 1 1 1 1 TMEM154 protein family Kelch_5 PF13854.6 KKK15450.1 - 0.00041 20.3 2.5 0.74 9.9 0.1 3.3 3 0 0 3 3 3 2 Kelch motif Kelch_1 PF01344.25 KKK15450.1 - 0.033 13.8 0.2 0.69 9.5 0.0 3.2 3 0 0 3 3 3 0 Kelch motif Gram_pos_anchor PF00746.21 KKK15450.1 - 0.036 14.0 2.1 0.13 12.3 2.1 2.0 1 0 0 1 1 1 0 LPXTG cell wall anchor motif DUF2407_C PF13373.6 KKK15450.1 - 0.13 12.4 0.0 0.25 11.5 0.0 1.4 1 0 0 1 1 1 0 DUF2407 C-terminal domain RIFIN PF02009.16 KKK15450.1 - 0.17 11.8 0.0 0.25 11.2 0.0 1.2 1 0 0 1 1 1 0 Rifin Gly-zipper_Omp PF13488.6 KKK15450.1 - 0.96 9.5 3.8 0.25 11.4 0.1 1.9 2 0 0 2 2 1 0 Glycine zipper Gly-zipper_OmpA PF13436.6 KKK15450.1 - 1.3 8.8 4.9 3.6 7.5 4.9 1.8 1 0 0 1 1 1 0 Glycine-zipper domain Rick_17kDa_Anti PF05433.15 KKK15450.1 - 2.8 7.9 6.7 0.82 9.6 2.6 2.3 2 0 0 2 2 2 0 Glycine zipper 2TM domain DUF974 PF06159.13 KKK15451.1 - 6.1e-79 265.3 0.0 7.2e-79 265.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF974) BNR_2 PF13088.6 KKK15462.1 - 1.1e-05 24.9 0.0 0.0058 16.0 0.0 2.8 1 1 2 3 3 3 2 BNR repeat-like domain BNR PF02012.20 KKK15462.1 - 2.4e-05 23.6 2.3 0.032 14.2 0.1 3.4 2 0 0 2 2 2 2 BNR/Asp-box repeat Sortilin-Vps10 PF15902.5 KKK15462.1 - 0.0042 15.9 0.0 0.41 9.4 0.0 2.3 2 0 0 2 2 2 2 Sortilin, neurotensin receptor 3, BNR_6 PF15899.5 KKK15462.1 - 0.0098 15.9 0.3 0.69 10.1 0.0 2.8 2 0 0 2 2 2 1 BNR-Asp box repeat Bys1 PF04681.12 KKK15463.1 - 3e-08 33.7 0.0 3.4e-08 33.6 0.0 1.1 1 0 0 1 1 1 1 Blastomyces yeast-phase-specific protein Imm65 PF15582.6 KKK15463.1 - 0.18 10.6 0.0 0.21 10.4 0.0 1.0 1 0 0 1 1 1 0 Immunity protein 65 Arylsulfotran_2 PF14269.6 KKK15464.1 - 3.7e-110 368.0 5.4 4.4e-110 367.7 5.4 1.1 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 KKK15464.1 - 8.1e-05 21.7 4.4 0.00048 19.1 4.3 1.9 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) SusE PF14292.6 KKK15464.1 - 0.16 12.2 0.4 0.53 10.5 0.0 2.0 2 0 0 2 2 2 0 SusE outer membrane protein DUF4988 PF16378.5 KKK15464.1 - 0.17 11.5 0.1 0.31 10.7 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function Fe-ADH PF00465.19 KKK15465.1 - 8e-98 327.6 0.0 9e-98 327.4 0.0 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 KKK15465.1 - 5.5e-16 59.0 0.0 8.1e-12 45.4 0.0 2.2 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Peripla_BP_6 PF13458.6 KKK15465.1 - 0.0013 18.5 0.0 0.0023 17.6 0.0 1.3 1 0 0 1 1 1 1 Periplasmic binding protein Pkinase PF00069.25 KKK15466.1 - 4.2e-64 216.5 0.0 4.7e-64 216.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK15466.1 - 1.8e-32 112.7 0.0 2.1e-32 112.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KKK15466.1 - 0.00029 20.2 0.0 0.00039 19.8 0.0 1.3 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 KKK15466.1 - 0.005 16.8 0.1 0.0079 16.1 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KKK15466.1 - 0.0056 16.1 0.2 0.01 15.2 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KKK15466.1 - 0.015 14.3 0.0 0.025 13.6 0.0 1.4 1 1 0 1 1 1 0 Haspin like kinase domain Seadorna_VP7 PF07387.11 KKK15466.1 - 0.093 11.8 0.0 0.16 11.0 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 Glyco_hydro_43 PF04616.14 KKK15467.1 - 6.6e-28 97.9 9.1 2e-20 73.3 0.9 2.1 2 0 0 2 2 2 2 Glycosyl hydrolases family 43 Ank_2 PF12796.7 KKK15468.1 - 5.6e-88 289.6 4.5 9e-22 77.5 0.2 8.9 4 2 3 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KKK15468.1 - 2.5e-74 244.7 7.0 9.9e-12 45.1 0.0 11.8 5 2 8 13 13 13 11 Ankyrin repeats (many copies) Ank_5 PF13857.6 KKK15468.1 - 3.4e-66 218.4 14.9 3.3e-08 33.6 0.1 13.5 4 2 11 15 15 15 14 Ankyrin repeats (many copies) Ank_3 PF13606.6 KKK15468.1 - 6.6e-61 195.1 2.9 5.9e-06 26.2 0.0 16.3 17 0 0 17 17 17 10 Ankyrin repeat Ank PF00023.30 KKK15468.1 - 9.8e-54 177.6 14.8 6e-08 32.8 0.0 14.5 16 0 0 16 16 16 7 Ankyrin repeat CorA PF01544.18 KKK15468.1 - 0.004 16.5 2.2 0.004 16.5 2.2 1.9 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein NPR1_interact PF15699.5 KKK15468.1 - 0.086 13.5 0.5 0.24 12.1 0.5 1.7 1 0 0 1 1 1 0 NPR1 interacting DcpS PF05652.12 KKK15470.1 - 3.3e-35 121.1 0.0 5.2e-35 120.4 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal DcpS_C PF11969.8 KKK15470.1 - 6.5e-31 107.2 0.0 1e-30 106.6 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding MT-A70 PF05063.14 KKK15471.1 - 2.5e-24 86.1 0.2 4.6e-24 85.3 0.2 1.5 1 0 0 1 1 1 1 MT-A70 PUF PF00806.19 KKK15472.1 - 1.4e-27 93.8 0.0 1.7e-05 24.3 0.0 6.1 6 0 0 6 6 6 5 Pumilio-family RNA binding repeat RRM_1 PF00076.22 KKK15472.1 - 2.7e-11 43.1 0.0 6e-11 42.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) YL1 PF05764.13 KKK15473.1 - 2.6e-62 211.1 28.4 2.6e-62 211.1 28.4 3.6 3 1 0 3 3 3 1 YL1 nuclear protein YL1_C PF08265.11 KKK15473.1 - 3.3e-12 45.9 0.5 9.9e-12 44.4 0.2 1.9 2 0 0 2 2 2 1 YL1 nuclear protein C-terminal domain Peptidase_C12 PF01088.21 KKK15474.1 - 2.5e-46 158.1 0.0 3.2e-46 157.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 ETC_C1_NDUFA4 PF04800.12 KKK15475.1 - 1.9e-36 124.2 1.3 2.8e-36 123.6 1.3 1.3 1 0 0 1 1 1 1 ETC complex I subunit conserved region MOZ_SAS PF01853.18 KKK15476.1 - 4.9e-79 264.2 0.0 7.3e-79 263.6 0.0 1.3 1 0 0 1 1 1 1 MOZ/SAS family Myb_Cef PF11831.8 KKK15476.1 - 4e-54 183.7 1.8 4e-54 183.7 1.8 3.0 3 0 0 3 3 3 1 pre-mRNA splicing factor component Tudor-knot PF11717.8 KKK15476.1 - 1.1e-21 76.5 0.0 3e-21 75.0 0.0 1.9 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain zf-MYST PF17772.1 KKK15476.1 - 6.6e-21 73.7 0.1 1.2e-20 72.9 0.1 1.4 1 0 0 1 1 1 1 MYST family zinc finger domain Myb_DNA-binding PF00249.31 KKK15476.1 - 1.3e-20 73.3 2.9 6.1e-09 35.9 0.2 3.5 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KKK15476.1 - 3.5e-18 65.6 2.1 1.6e-11 44.3 0.4 2.8 1 1 1 2 2 2 2 Myb-like DNA-binding domain Acetyltransf_7 PF13508.7 KKK15476.1 - 0.017 15.5 0.0 0.043 14.2 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KKK15476.1 - 0.039 14.2 0.0 0.11 12.8 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family F1F0-ATPsyn_F PF10791.9 KKK15477.1 - 1.4e-32 112.0 0.1 3.4e-32 110.8 0.1 1.7 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi RNase_H2_suC PF08615.11 KKK15478.1 - 4.4e-29 101.5 0.0 5.4e-29 101.2 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Nop53 PF07767.11 KKK15479.1 - 2.9e-88 296.9 38.8 1.7e-75 254.9 27.0 4.2 3 1 1 4 4 4 2 Nop53 (60S ribosomal biogenesis) RNase_T PF00929.24 KKK15479.1 - 2.5e-16 60.6 0.0 6.1e-15 56.2 0.0 2.6 2 1 0 2 2 2 1 Exonuclease GCV_T PF01571.21 KKK15480.1 - 1.8e-05 24.3 0.0 2.8e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain DCP2 PF05026.13 KKK15481.1 - 3.3e-30 104.2 1.1 5.7e-30 103.5 1.1 1.4 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.28 KKK15481.1 - 8.3e-18 64.7 0.0 1.7e-17 63.7 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain DUF4112 PF13430.6 KKK15482.1 - 5.2e-34 116.7 0.6 6.6e-34 116.3 0.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) AgrD PF05931.11 KKK15482.1 - 0.64 10.1 3.4 1.1 9.4 0.7 2.3 2 0 0 2 2 2 0 Staphylococcal AgrD protein CTU2 PF10288.9 KKK15483.1 - 4.6e-10 39.7 1.5 3.4e-09 36.9 0.1 2.1 1 1 1 2 2 2 1 Cytoplasmic tRNA 2-thiolation protein 2 DSPc PF00782.20 KKK15484.1 - 4.1e-23 81.7 0.0 8.4e-22 77.4 0.0 2.1 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Sugar_tr PF00083.24 KKK15487.1 - 4.7e-35 121.3 10.5 5.2e-35 121.2 10.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter Trp_oprn_chp PF09534.10 KKK15487.1 - 0.0097 15.7 5.9 0.014 15.2 5.9 1.3 1 0 0 1 1 1 1 Tryptophan-associated transmembrane protein (Trp_oprn_chp) TMIE PF16038.5 KKK15487.1 - 0.097 12.5 0.6 2.8 7.8 0.0 2.7 3 0 0 3 3 3 0 TMIE protein DUF998 PF06197.13 KKK15487.1 - 4.8 6.7 24.6 15 5.2 18.8 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF998) Pkinase PF00069.25 KKK15492.1 - 2.8e-20 72.8 0.0 3.5e-20 72.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK15492.1 - 2e-16 60.1 0.0 2.6e-16 59.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KKK15492.1 - 0.00054 19.4 0.0 0.00081 18.8 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KKK15492.1 - 0.0015 17.9 0.0 0.0029 17.0 0.0 1.4 1 1 0 1 1 1 1 Kinase-like zf-HC5HC2H_2 PF13832.6 KKK15500.1 - 3.6e-22 78.6 0.6 3.6e-22 78.6 0.6 4.2 5 0 0 5 5 5 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 KKK15500.1 - 4.2e-20 71.8 1.8 4.2e-20 71.8 1.8 4.7 5 0 0 5 5 5 1 PHD-like zinc-binding domain BAH PF01426.18 KKK15500.1 - 6.7e-18 64.7 0.1 1.4e-17 63.7 0.1 1.6 1 0 0 1 1 1 1 BAH domain PHD PF00628.29 KKK15500.1 - 9e-11 41.5 20.3 6.5e-07 29.1 5.7 5.6 7 0 0 7 7 7 3 PHD-finger PHD_2 PF13831.6 KKK15500.1 - 1.9e-09 36.9 5.0 1.9e-09 36.9 5.0 4.6 5 0 0 5 5 5 1 PHD-finger Myb_DNA-binding PF00249.31 KKK15500.1 - 2.7e-05 24.3 0.1 8e-05 22.7 0.1 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain FYVE_2 PF02318.16 KKK15500.1 - 0.0047 17.1 1.9 0.0047 17.1 1.9 4.4 5 0 0 5 5 5 2 FYVE-type zinc finger C1_1 PF00130.22 KKK15500.1 - 0.0059 16.5 2.2 0.0059 16.5 2.2 6.3 7 1 1 8 8 8 2 Phorbol esters/diacylglycerol binding domain (C1 domain) ELM2 PF01448.24 KKK15500.1 - 2.3 9.0 5.3 13 6.6 0.4 4.1 3 2 0 3 3 3 0 ELM2 domain DUF202 PF02656.15 KKK15502.1 - 2.9e-05 24.4 2.9 2.9e-05 24.4 2.9 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF202) DUF998 PF06197.13 KKK15502.1 - 0.021 14.4 4.8 0.78 9.3 1.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF998) 6PF2K PF01591.18 KKK15503.1 - 5.7e-68 228.6 0.0 4.8e-48 163.4 0.0 2.2 2 0 0 2 2 2 2 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 KKK15503.1 - 1.1e-31 110.1 0.1 1.3e-23 83.8 0.0 2.5 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 KKK15503.1 - 0.00016 21.8 0.0 0.055 13.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain KTI12 PF08433.10 KKK15503.1 - 0.06 12.8 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 DSBA PF01323.20 KKK15504.1 - 4e-31 108.3 0.0 9.7e-15 54.8 0.0 2.0 2 0 0 2 2 2 2 DSBA-like thioredoxin domain OmpA_like PF16961.5 KKK15504.1 - 0.054 13.2 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Putative OmpA-OmpF-like porin family IPPT PF01715.17 KKK15504.1 - 0.09 12.6 0.0 0.26 11.1 0.0 1.7 1 1 0 1 1 1 0 IPP transferase Frag1 PF10277.9 KKK15505.1 - 1.7e-11 44.1 0.0 2.9e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family Trypan_PARP PF05887.11 KKK15505.1 - 6e-06 26.3 2.2 1.1e-05 25.4 2.2 1.5 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) GGN PF15685.5 KKK15505.1 - 0.0064 15.6 0.4 0.008 15.3 0.4 1.1 1 0 0 1 1 1 1 Gametogenetin SPESP1 PF15754.5 KKK15505.1 - 0.25 10.5 1.7 0.34 10.0 1.7 1.1 1 0 0 1 1 1 0 Sperm equatorial segment protein 1 VTC PF09359.10 KKK15506.1 - 9.2e-88 294.2 0.1 1.5e-87 293.5 0.1 1.4 1 0 0 1 1 1 1 VTC domain DUF202 PF02656.15 KKK15506.1 - 1.9e-12 47.5 4.4 1.9e-12 47.5 4.4 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF202) SPX PF03105.19 KKK15506.1 - 0.00022 21.3 19.5 0.0064 16.5 0.0 4.4 3 1 1 5 5 5 3 SPX domain DUF4944 PF16302.5 KKK15506.1 - 0.11 12.6 0.1 0.26 11.4 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4944) INCENP_ARK-bind PF03941.15 KKK15506.1 - 0.57 10.2 0.0 0.57 10.2 0.0 2.6 3 0 0 3 3 3 0 Inner centromere protein, ARK binding region NUDIX PF00293.28 KKK15507.1 - 1.9e-09 37.7 0.0 3.7e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain CBFD_NFYB_HMF PF00808.23 KKK15507.1 - 0.00082 19.6 0.0 0.0019 18.4 0.0 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-W PF15510.6 KKK15507.1 - 0.0011 19.2 0.3 0.0024 18.1 0.1 1.7 2 0 0 2 2 2 1 CENP-W protein Ax_dynein_light PF10211.9 KKK15508.1 - 0.36 10.8 6.6 0.69 9.8 6.6 1.4 1 0 0 1 1 1 0 Axonemal dynein light chain SurA_N_3 PF13624.6 KKK15508.1 - 0.69 9.7 5.7 1.3 8.8 4.8 1.8 1 1 1 2 2 2 0 SurA N-terminal domain RPN7 PF10602.9 KKK15508.1 - 1.4 8.5 5.3 0.61 9.8 0.5 2.2 1 1 1 2 2 2 0 26S proteasome subunit RPN7 Muted PF14942.6 KKK15508.1 - 3.3 8.1 9.6 2.6 8.4 7.9 1.7 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein SNF2_N PF00176.23 KKK15510.1 - 6.8e-51 173.0 0.3 1.6e-49 168.5 0.3 2.7 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KKK15510.1 - 1.1e-16 61.1 0.1 2.1e-15 57.0 0.0 3.0 4 0 0 4 4 4 1 Helicase conserved C-terminal domain ResIII PF04851.15 KKK15510.1 - 5.5e-06 26.5 0.0 1.5e-05 25.1 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.25 KKK15510.1 - 3.3e-05 23.7 10.5 3.3e-05 23.7 10.5 2.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) AAA_34 PF13872.6 KKK15510.1 - 0.0014 17.5 0.0 0.0036 16.3 0.0 1.6 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 LRR_4 PF12799.7 KKK15511.1 - 0.002 18.5 7.6 17 6.0 0.1 6.5 5 1 3 8 8 8 1 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KKK15511.1 - 0.022 14.8 7.7 8.4 6.7 0.0 5.9 8 0 0 8 8 8 0 Leucine Rich repeat FYVE PF01363.21 KKK15511.1 - 0.4 10.9 3.3 0.23 11.6 0.7 2.0 2 1 0 2 2 2 0 FYVE zinc finger ATP-synt_B PF00430.18 KKK15511.1 - 4 7.5 8.7 8.2 6.5 8.7 1.4 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) Trypan_PARP PF05887.11 KKK15511.1 - 5.5 7.0 12.5 1.6 8.7 3.2 2.3 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) EF-hand_4 PF12763.7 KKK15512.1 - 6.2e-27 93.6 0.0 1e-12 47.9 0.0 2.4 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand DUF1720 PF08226.11 KKK15512.1 - 3.6e-06 27.3 130.9 5.7e-05 23.4 43.0 6.6 3 2 1 4 4 4 1 Domain of unknown function (DUF1720) EF-hand_7 PF13499.6 KKK15512.1 - 4.9e-05 23.7 1.9 0.031 14.7 0.0 3.7 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 KKK15512.1 - 0.012 15.1 0.0 5.1 6.9 0.0 2.5 2 0 0 2 2 2 0 EF hand E3_binding PF02817.17 KKK15512.1 - 0.071 13.5 0.3 0.43 11.0 0.1 2.4 2 0 0 2 2 2 0 e3 binding domain ATP-synt_B PF00430.18 KKK15513.1 - 5.1 7.2 7.2 8.8 6.4 7.2 1.3 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) RNA_pol_L_2 PF13656.6 KKK15514.1 - 1.4e-24 85.6 0.0 2.4e-24 84.9 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 KKK15514.1 - 1.4e-08 34.0 0.0 3e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain IF4E PF01652.18 KKK15515.1 - 5.7e-55 185.5 0.0 1e-54 184.7 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E SelP_N PF04592.14 KKK15515.1 - 1.7 8.0 14.8 2.6 7.4 14.8 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Peptidase_C48 PF02902.19 KKK15516.1 - 2.8e-31 109.1 0.0 1.9e-30 106.3 0.0 2.2 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain GGACT PF06094.12 KKK15517.1 - 9.8e-06 26.2 1.2 0.00018 22.1 1.2 2.0 1 1 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like DEP PF00610.21 KKK15520.1 - 1.5e-29 101.9 0.7 2.7e-29 101.0 0.7 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Fungal_trans PF04082.18 KKK15521.1 - 1e-09 37.8 0.3 2e-09 36.9 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain SBP_bac_10 PF07596.11 KKK15521.1 - 0.06 13.3 0.0 0.084 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1559) IML1 PF12257.8 KKK15522.1 - 3.9e-112 374.0 0.0 5.1e-112 373.7 0.0 1.1 1 0 0 1 1 1 1 Vacuolar membrane-associated protein Iml1 Fungal_trans PF04082.18 KKK15523.1 - 1.7e-18 66.7 0.1 3.4e-18 65.7 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK15523.1 - 6.7e-09 35.7 12.1 1.2e-08 35.0 12.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PspB PF06667.12 KKK15523.1 - 0.16 12.0 1.0 3.2 7.9 0.0 2.4 2 0 0 2 2 2 0 Phage shock protein B TMPIT PF07851.13 KKK15523.1 - 0.93 8.7 3.1 2.7 7.2 1.6 2.0 2 0 0 2 2 2 0 TMPIT-like protein Vezatin PF12632.7 KKK15551.1 - 9.4e-68 228.6 0.4 2.9e-67 227.0 0.0 2.1 3 0 0 3 3 3 1 Mysoin-binding motif of peroxisomes PCNA_N PF00705.18 KKK15551.1 - 6.8e-54 181.0 2.5 1.3e-53 180.0 2.5 1.5 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.15 KKK15551.1 - 3.7e-51 172.6 0.0 7.5e-51 171.6 0.0 1.5 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, C-terminal domain Rad1 PF02144.16 KKK15551.1 - 9.3e-05 21.6 0.1 0.0015 17.6 0.0 2.1 1 1 1 2 2 2 1 Repair protein Rad1/Rec1/Rad17 Rad9 PF04139.13 KKK15551.1 - 0.00018 21.1 0.0 0.00028 20.4 0.0 1.2 1 0 0 1 1 1 1 Rad9 Hus1 PF04005.12 KKK15551.1 - 0.012 14.8 0.1 0.044 12.9 0.0 1.7 1 1 0 2 2 2 0 Hus1-like protein PLDc_N PF13396.6 KKK15551.1 - 0.14 12.2 0.2 0.32 11.0 0.2 1.6 1 0 0 1 1 1 0 Phospholipase_D-nuclease N-terminal CH PF00307.31 KKK15552.1 - 5.3e-05 23.4 0.0 0.00031 20.9 0.0 2.4 2 0 0 2 2 2 1 Calponin homology (CH) domain Glyco_hydro_38N PF01074.22 KKK15564.1 - 8.4e-89 297.8 1.3 8.4e-89 297.8 1.3 1.9 3 0 0 3 3 3 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 KKK15564.1 - 1.4e-59 201.8 0.0 7.6e-59 199.4 0.0 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 KKK15564.1 - 1.5e-26 92.3 0.0 2.9e-26 91.4 0.0 1.5 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 KKK15564.1 - 1e-06 28.7 0.0 2.4e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain Glyco_hydro_57 PF03065.15 KKK15564.1 - 0.13 11.4 0.0 0.34 10.1 0.0 1.6 1 1 0 1 1 1 0 Glycosyl hydrolase family 57 GUN4 PF05419.12 KKK15564.1 - 2.3 8.3 5.0 3.5 7.7 0.1 3.1 4 0 0 4 4 4 0 GUN4-like Spt20 PF12090.8 KKK15565.1 - 0.045 13.4 7.4 0.097 12.3 7.4 1.5 1 0 0 1 1 1 0 Spt20 family FixO PF02433.15 KKK15565.1 - 0.13 11.7 2.0 1.1 8.7 0.1 2.3 2 0 0 2 2 2 0 Cytochrome C oxidase, mono-heme subunit/FixO ArAE_2_N PF10337.9 KKK15565.1 - 0.26 10.3 0.4 0.44 9.5 0.4 1.3 1 0 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal TFIIA PF03153.13 KKK15565.1 - 0.62 10.0 15.6 1.1 9.2 15.6 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ISK_Channel PF02060.15 KKK15565.1 - 0.62 9.8 1.8 1.4 8.6 0.3 2.1 2 0 0 2 2 2 0 Slow voltage-gated potassium channel Activator_LAG-3 PF11498.8 KKK15565.1 - 4.5 6.1 20.6 6.6 5.6 16.4 2.3 2 0 0 2 2 2 0 Transcriptional activator LAG-3 LETM1 PF07766.13 KKK15566.1 - 7.7e-103 343.5 0.1 7.7e-103 343.5 0.1 1.6 2 0 0 2 2 2 1 LETM1-like protein SAP PF02037.27 KKK15566.1 - 0.00036 20.2 0.0 0.0061 16.3 0.0 2.8 3 0 0 3 3 3 1 SAP domain DUF2838 PF10998.8 KKK15567.1 - 5.9e-41 139.2 11.7 5.9e-41 139.2 11.7 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2838) Tropomyosin_1 PF12718.7 KKK15567.1 - 0.0047 17.1 0.9 0.0082 16.3 0.9 1.3 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.20 KKK15567.1 - 0.11 11.9 2.3 0.17 11.2 2.3 1.3 1 0 0 1 1 1 0 Tropomyosin Exonuc_VII_L PF02601.15 KKK15567.1 - 0.14 11.7 0.1 0.18 11.3 0.1 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Bacillus_HBL PF05791.11 KKK15567.1 - 0.19 11.6 0.1 0.38 10.6 0.1 1.5 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) Atg14 PF10186.9 KKK15567.1 - 0.2 10.7 2.1 0.3 10.1 2.1 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Val_tRNA-synt_C PF10458.9 KKK15567.1 - 1.5 9.1 7.6 6.7 7.1 0.1 2.4 2 0 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm DUF2841 PF11001.8 KKK15568.1 - 2.9e-49 166.2 0.1 4.8e-49 165.5 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) AP_endonuc_2 PF01261.24 KKK15569.1 - 3e-29 102.0 0.4 4.4e-29 101.4 0.4 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Sugar_tr PF00083.24 KKK15570.1 - 6.2e-139 463.7 21.1 7.1e-139 463.5 21.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKK15570.1 - 4e-29 101.7 63.7 2.3e-26 92.6 35.5 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Choline_kinase PF01633.20 KKK15571.1 - 1.5e-45 155.5 0.0 3.6e-44 150.9 0.0 2.1 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.23 KKK15571.1 - 2.5e-09 37.4 0.7 7.3e-09 35.9 0.5 1.9 2 1 0 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.20 KKK15571.1 - 0.16 11.2 0.0 0.7 9.2 0.0 1.9 1 1 0 1 1 1 0 Ecdysteroid kinase ETF_QO PF05187.13 KKK15575.1 - 5.2e-30 103.6 0.1 9.1e-30 102.9 0.1 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S RRM_1 PF00076.22 KKK15575.1 - 8.5e-18 64.0 0.0 1.2e-07 31.5 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DAO PF01266.24 KKK15575.1 - 7.8e-08 32.3 0.2 0.00061 19.5 0.4 2.3 1 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KKK15575.1 - 1.5e-07 31.5 0.0 6.3e-07 29.5 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KKK15575.1 - 4.4e-07 29.3 0.3 0.0069 15.5 0.9 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 KKK15575.1 - 2.2e-05 23.8 0.0 7.2e-05 22.2 0.0 1.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KKK15575.1 - 0.0004 19.2 0.4 0.00067 18.5 0.4 1.3 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.17 KKK15575.1 - 0.00043 19.6 0.0 0.02 14.1 0.0 2.1 2 0 0 2 2 2 1 Thi4 family FAD_oxidored PF12831.7 KKK15575.1 - 0.00044 19.7 0.0 0.00072 19.0 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KKK15575.1 - 0.00055 19.3 0.0 0.0012 18.2 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 KKK15575.1 - 0.0018 18.8 0.1 1.8 9.2 0.0 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KKK15575.1 - 0.0024 17.9 0.0 0.0061 16.5 0.0 1.7 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 KKK15575.1 - 0.0084 15.4 0.4 0.013 14.8 0.4 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KKK15575.1 - 0.072 12.1 0.3 0.11 11.5 0.3 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Trp_halogenase PF04820.14 KKK15575.1 - 0.083 11.7 0.0 0.26 10.1 0.1 1.7 2 0 0 2 2 2 0 Tryptophan halogenase GIDA PF01134.22 KKK15575.1 - 0.23 10.5 0.4 0.35 9.9 0.4 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A AICARFT_IMPCHas PF01808.18 KKK15576.1 - 3.4e-91 305.8 0.0 5.4e-91 305.1 0.0 1.3 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.22 KKK15576.1 - 4.6e-25 87.6 0.0 8.8e-25 86.7 0.0 1.5 1 0 0 1 1 1 1 MGS-like domain Clathrin PF00637.20 KKK15577.1 - 1e-198 651.2 34.1 7.9e-32 110.1 2.3 7.7 7 0 0 7 7 7 7 Region in Clathrin and VPS Clathrin_propel PF01394.20 KKK15577.1 - 2.6e-38 128.5 1.0 1.5e-08 34.5 0.0 6.7 6 0 0 6 6 6 6 Clathrin propeller repeat Clathrin_H_link PF13838.6 KKK15577.1 - 7.8e-32 109.0 4.0 8e-32 109.0 0.3 3.1 3 0 0 3 3 3 1 Clathrin-H-link TPR_14 PF13428.6 KKK15577.1 - 1.7e-05 25.2 1.6 0.39 11.7 0.1 6.5 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.6 KKK15577.1 - 0.0002 21.3 1.4 0.38 11.1 0.0 5.3 4 0 0 4 4 4 1 Tetratricopeptide repeat Coatomer_WDAD PF04053.14 KKK15577.1 - 0.0075 15.4 4.8 0.17 10.9 0.3 3.5 4 0 0 4 4 4 1 Coatomer WD associated region TPR_7 PF13176.6 KKK15577.1 - 0.057 13.5 4.8 1e+02 3.2 0.0 6.0 6 0 0 6 6 6 0 Tetratricopeptide repeat Utp13 PF08625.11 KKK15577.1 - 0.11 12.5 1.9 5.7 6.8 0.1 4.1 4 0 0 4 4 4 0 Utp13 specific WD40 associated domain TPR_1 PF00515.28 KKK15577.1 - 0.65 9.9 3.4 6.6 6.7 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat Vps39_1 PF10366.9 KKK15577.1 - 1.8 8.9 11.2 7.5 6.9 0.0 5.8 5 1 1 6 6 6 0 Vacuolar sorting protein 39 domain 1 DnaJ PF00226.31 KKK15578.1 - 4.4e-13 49.2 0.0 9.5e-13 48.1 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain Gemini_mov PF01708.16 KKK15578.1 - 0.17 11.7 0.0 0.31 10.8 0.0 1.5 1 0 0 1 1 1 0 Geminivirus putative movement protein Mus7 PF09462.10 KKK15579.1 - 1.9e-227 757.0 0.0 2.8e-227 756.5 0.0 1.2 1 0 0 1 1 1 1 Mus7/MMS22 family PAPA-1 PF04795.12 KKK15580.1 - 1.4e-32 112.3 6.8 1.4e-32 112.3 6.8 3.3 2 1 0 2 2 2 1 PAPA-1-like conserved region Pex14_N PF04695.13 KKK15581.1 - 2.3e-40 138.8 0.1 2.3e-40 138.8 0.1 2.7 3 0 0 3 3 3 2 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF1917 PF08939.10 KKK15581.1 - 0.086 12.7 0.8 0.15 11.9 0.5 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF1917) Tmemb_cc2 PF10267.9 KKK15581.1 - 7.9 5.5 5.9 0.97 8.5 0.0 2.2 3 1 1 4 4 4 0 Predicted transmembrane and coiled-coil 2 protein BNR PF02012.20 KKK15582.1 - 0.059 13.4 0.1 0.49 10.6 0.1 2.7 1 0 0 1 1 1 0 BNR/Asp-box repeat Aldolase_II PF00596.21 KKK15583.1 - 8.1e-07 29.2 0.0 1.2e-06 28.6 0.0 1.3 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain DUF4050 PF13259.6 KKK15584.1 - 4e-50 170.7 24.8 3.1e-49 167.8 24.8 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF4050) SMBP PF16785.5 KKK15584.1 - 0.0012 19.0 1.5 0.0025 18.0 1.2 1.6 2 0 0 2 2 2 1 Small metal-binding protein AAA PF00004.29 KKK15585.1 - 5.4e-41 140.1 0.0 2e-37 128.6 0.0 2.9 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KKK15585.1 - 1.8e-10 40.4 0.4 5.4e-10 38.9 0.0 2.1 2 0 0 2 2 2 1 AAA+ lid domain AAA_16 PF13191.6 KKK15585.1 - 2.1e-05 25.0 0.4 0.0019 18.6 0.1 3.5 2 1 0 3 3 3 1 AAA ATPase domain AAA_33 PF13671.6 KKK15585.1 - 3e-05 24.2 0.0 0.0036 17.5 0.0 2.9 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 KKK15585.1 - 5.1e-05 23.1 0.0 0.00017 21.3 0.0 1.9 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KKK15585.1 - 0.00024 21.4 0.2 0.029 14.6 0.1 3.1 1 1 1 2 2 2 1 AAA domain TIP49 PF06068.13 KKK15585.1 - 0.00031 20.0 0.0 0.0007 18.9 0.0 1.6 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_5 PF07728.14 KKK15585.1 - 0.0012 18.8 0.0 0.0032 17.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.6 KKK15585.1 - 0.0064 16.9 1.7 0.12 12.8 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_28 PF13521.6 KKK15585.1 - 0.0082 16.4 0.1 0.043 14.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 KKK15585.1 - 0.0082 15.9 0.0 0.015 15.0 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.6 KKK15585.1 - 0.018 15.1 0.0 0.083 12.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 KKK15585.1 - 0.019 14.3 0.0 0.045 13.1 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 KKK15585.1 - 0.028 14.8 0.0 0.081 13.3 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_2 PF07724.14 KKK15585.1 - 0.029 14.5 0.0 0.53 10.4 0.0 2.9 3 1 0 3 3 3 0 AAA domain (Cdc48 subfamily) AAA_18 PF13238.6 KKK15585.1 - 0.051 14.1 0.0 0.13 12.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KKK15585.1 - 0.075 12.8 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain IPT PF01745.16 KKK15585.1 - 0.098 12.0 0.1 0.54 9.6 0.0 2.0 2 0 0 2 2 2 0 Isopentenyl transferase TsaE PF02367.17 KKK15585.1 - 0.12 12.4 0.1 0.35 10.9 0.0 1.8 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE zf-CCCH PF00642.24 KKK15586.1 - 1.8e-08 34.1 2.2 3.5e-08 33.1 2.2 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_3 PF13920.6 KKK15586.1 - 4.3e-07 29.7 6.6 7.9e-07 28.8 6.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KKK15586.1 - 2.2e-06 27.4 8.9 3.7e-06 26.7 8.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KKK15586.1 - 2.7e-06 27.3 7.0 5.4e-06 26.3 7.0 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KKK15586.1 - 6.4e-06 26.0 8.8 1.1e-05 25.3 8.8 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KKK15586.1 - 8.4e-06 25.6 10.6 1.5e-05 24.8 10.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf_CCCH_4 PF18345.1 KKK15586.1 - 1.6e-05 24.8 5.1 3.5e-05 23.7 5.1 1.7 1 0 0 1 1 1 1 Zinc finger domain zf-RING_10 PF16685.5 KKK15586.1 - 2.1e-05 24.6 3.9 5e-05 23.3 3.9 1.6 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-RING_2 PF13639.6 KKK15586.1 - 0.0004 20.7 7.2 0.0004 20.7 7.2 1.6 2 0 0 2 2 2 1 Ring finger domain zf-CCCH_4 PF18044.1 KKK15586.1 - 0.00087 19.0 2.1 0.00087 19.0 2.1 2.1 2 0 0 2 2 1 1 CCCH-type zinc finger Prok-RING_4 PF14447.6 KKK15586.1 - 0.0018 18.1 6.5 0.0031 17.3 6.5 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 ProSAAS PF07259.12 KKK15586.1 - 0.0082 16.1 0.0 0.024 14.6 0.0 1.7 1 0 0 1 1 1 1 ProSAAS precursor zf-C3HC4_4 PF15227.6 KKK15586.1 - 0.027 14.6 9.0 0.06 13.5 9.0 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-Nse PF11789.8 KKK15586.1 - 0.13 12.1 2.0 0.24 11.2 2.0 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-rbx1 PF12678.7 KKK15586.1 - 0.33 11.3 4.8 0.63 10.4 4.8 1.4 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-CCCH_2 PF14608.6 KKK15586.1 - 3.2 8.4 8.4 0.19 12.3 3.0 1.8 2 0 0 2 2 1 0 RNA-binding, Nab2-type zinc finger UCH PF00443.29 KKK15587.1 - 9.9e-60 202.2 0.0 3.6e-59 200.4 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 KKK15587.1 - 9.8e-15 54.9 0.0 5.3e-14 52.6 0.0 2.3 2 0 0 2 2 2 1 DUSP domain UCH_1 PF13423.6 KKK15587.1 - 2.2e-10 40.7 0.0 0.00035 20.3 0.0 3.4 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase USP7_C2 PF14533.6 KKK15587.1 - 0.0015 18.3 0.4 0.0032 17.2 0.1 1.7 2 0 0 2 2 2 1 Ubiquitin-specific protease C-terminal Chitin_synth_2 PF03142.15 KKK15588.1 - 2.2e-246 818.6 2.5 3e-246 818.1 2.5 1.2 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.21 KKK15588.1 - 7e-72 242.7 0.0 2.6e-71 240.8 0.0 1.8 1 1 0 1 1 1 1 Myosin head (motor domain) DEK_C PF08766.11 KKK15588.1 - 6.5e-18 64.4 0.2 2.8e-17 62.4 0.3 2.1 2 0 0 2 2 2 1 DEK C terminal domain Cyt-b5 PF00173.28 KKK15588.1 - 1.4e-17 63.6 0.3 1.6e-14 53.8 0.1 2.7 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_tranf_2_3 PF13641.6 KKK15588.1 - 4.7e-10 39.8 0.1 1.3e-09 38.3 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 KKK15588.1 - 3.8e-09 36.8 4.4 3.8e-09 36.8 4.4 1.9 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 KKK15588.1 - 0.0023 17.8 0.0 0.16 11.8 0.0 2.5 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 KKK15588.1 - 0.0051 16.3 0.0 0.026 14.0 0.0 2.2 3 0 0 3 3 3 1 Glycosyl transferase family 21 RsgA_GTPase PF03193.16 KKK15588.1 - 0.027 14.4 0.2 0.078 12.9 0.0 1.8 2 0 0 2 2 2 0 RsgA GTPase AAA_16 PF13191.6 KKK15588.1 - 0.059 13.8 0.1 0.21 11.9 0.1 1.9 2 0 0 2 2 2 0 AAA ATPase domain Dynactin PF12455.8 KKK15589.1 - 1.4e-99 333.0 8.8 1.4e-99 333.0 8.8 4.1 3 1 1 4 4 4 1 Dynein associated protein CAP_GLY PF01302.25 KKK15589.1 - 1.9e-23 82.3 0.4 3.5e-23 81.4 0.4 1.4 1 0 0 1 1 1 1 CAP-Gly domain DUF3452 PF11934.8 KKK15589.1 - 0.4 10.2 2.3 2.8 7.5 0.6 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3452) HALZ PF02183.18 KKK15589.1 - 0.5 10.6 0.0 0.5 10.6 0.0 7.8 8 1 2 10 10 10 0 Homeobox associated leucine zipper AlgF PF11182.8 KKK15589.1 - 1.4 8.6 4.3 0.41 10.4 0.4 2.1 2 0 0 2 2 2 0 Alginate O-acetyl transferase AlgF Sugar_tr PF00083.24 KKK15590.1 - 5.7e-108 361.7 18.6 6.4e-108 361.5 18.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKK15590.1 - 2e-21 76.3 27.6 2.8e-21 75.8 27.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Chorismate_synt PF01264.21 KKK15591.1 - 1.1e-138 461.5 0.0 1.2e-138 461.3 0.0 1.0 1 0 0 1 1 1 1 Chorismate synthase BPL_LplA_LipB PF03099.19 KKK15592.1 - 1e-07 31.9 0.0 2.2e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family DUF2264 PF10022.9 KKK15593.1 - 3.4e-141 470.4 0.0 4.1e-141 470.1 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2264) FAT PF02259.23 KKK15595.1 - 3.5e-138 460.5 0.5 3.5e-138 460.5 0.5 2.2 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.27 KKK15595.1 - 9.4e-71 238.5 0.1 1.9e-70 237.5 0.1 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.8 KKK15595.1 - 1.5e-67 226.5 3.2 9.5e-63 210.9 0.4 5.2 4 1 1 5 5 5 2 Domain of unknown function (DUF3385) FRB_dom PF08771.11 KKK15595.1 - 5.1e-43 145.5 8.0 1.7e-42 143.9 0.2 4.6 5 0 0 5 5 3 1 FKBP12-rapamycin binding domain HEAT_2 PF13646.6 KKK15595.1 - 1.6e-14 54.0 12.6 0.00014 22.2 0.0 9.1 8 2 1 9 9 8 3 HEAT repeats FATC PF02260.20 KKK15595.1 - 9.1e-14 51.0 1.0 2.6e-13 49.5 1.0 1.9 1 0 0 1 1 1 1 FATC domain HEAT_EZ PF13513.6 KKK15595.1 - 1e-13 51.4 14.2 0.0033 17.9 0.0 9.8 11 1 0 11 11 9 3 HEAT-like repeat HEAT PF02985.22 KKK15595.1 - 1.3e-10 40.6 22.8 0.0047 17.1 0.0 12.2 14 0 0 14 14 11 2 HEAT repeat Adaptin_N PF01602.20 KKK15595.1 - 8.3e-07 27.9 9.6 0.00049 18.8 0.4 4.7 3 2 1 4 4 4 3 Adaptin N terminal region CLASP_N PF12348.8 KKK15595.1 - 0.00021 20.9 0.8 1 8.8 0.0 4.7 5 0 0 5 5 5 1 CLASP N terminal MMS19_C PF12460.8 KKK15595.1 - 0.0025 17.0 5.6 0.11 11.6 0.0 3.9 3 1 0 3 3 3 1 RNAPII transcription regulator C-terminal Tti2 PF10521.9 KKK15595.1 - 0.003 17.2 1.2 14 5.1 0.0 4.8 3 1 2 5 5 5 0 Tti2 family Sec7_N PF12783.7 KKK15595.1 - 0.0065 16.4 0.0 0.52 10.2 0.0 3.6 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal TPR_11 PF13414.6 KKK15595.1 - 0.031 14.0 0.5 0.63 9.8 0.0 3.0 2 0 0 2 2 2 0 TPR repeat DUF3730 PF12530.8 KKK15595.1 - 0.046 13.3 0.9 4.1 6.9 0.0 4.1 5 0 0 5 5 5 0 Protein of unknown function (DUF3730) PDZ_6 PF17820.1 KKK15595.1 - 0.071 13.0 0.0 0.18 11.7 0.0 1.7 1 0 0 1 1 1 0 PDZ domain DUF3150 PF11348.8 KKK15595.1 - 0.1 11.8 0.0 0.24 10.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3150) DUF1997 PF09366.10 KKK15595.1 - 0.12 12.5 0.1 0.99 9.5 0.0 2.6 3 0 0 3 3 1 0 Protein of unknown function (DUF1997) TPR_14 PF13428.6 KKK15595.1 - 0.22 12.4 11.7 5 8.2 0.0 5.9 5 1 1 6 6 4 0 Tetratricopeptide repeat SH3_1 PF00018.28 KKK15596.1 - 1.2e-09 37.7 0.1 3e-09 36.4 0.1 1.8 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KKK15596.1 - 4.4e-09 35.9 0.0 8.7e-09 34.9 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 KKK15596.1 - 6.7e-09 35.5 0.1 1.9e-08 34.1 0.1 1.8 1 0 0 1 1 1 1 Variant SH3 domain DUF913 PF06025.12 KKK15598.1 - 4.3e-132 440.6 0.0 4.3e-132 440.6 0.0 5.3 5 1 0 5 5 5 2 Domain of Unknown Function (DUF913) DUF908 PF06012.12 KKK15598.1 - 5.2e-115 384.7 1.1 5.2e-115 384.7 1.1 2.6 3 0 0 3 3 3 1 Domain of Unknown Function (DUF908) HECT PF00632.25 KKK15598.1 - 5.7e-93 311.8 0.0 9.7e-93 311.0 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) UBM PF14377.6 KKK15598.1 - 1.5e-30 103.6 21.8 1.9e-10 39.8 1.8 4.6 3 0 0 3 3 3 3 Ubiquitin binding region NARP1 PF12569.8 KKK15598.1 - 0.29 10.0 6.1 0.64 8.9 6.1 1.5 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 AP-5_subunit_s1 PF15001.6 KKK15598.1 - 3.1 7.7 6.1 3.3 7.7 4.0 2.2 2 0 0 2 2 2 0 AP-5 complex subunit sigma-1 Pribosyltran_N PF13793.6 KKK15599.1 - 4.7e-46 155.5 1.5 1.5e-44 150.7 0.1 2.5 3 0 0 3 3 3 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 KKK15599.1 - 1.4e-41 142.5 2.4 6.3e-35 120.9 1.2 2.5 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 KKK15599.1 - 1.1e-17 64.0 2.6 1.7e-16 60.2 1.9 2.5 2 1 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.6 KKK15599.1 - 3e-05 23.6 0.3 5.3e-05 22.8 0.3 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Chlorosome_CsmC PF11098.8 KKK15599.1 - 0.24 11.4 3.4 0.44 10.5 3.4 1.3 1 0 0 1 1 1 0 Chlorosome envelope protein C SH3_1 PF00018.28 KKK15615.1 - 5.6e-07 29.1 1.0 4.2e-06 26.3 0.0 2.4 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 KKK15615.1 - 0.0008 19.2 0.0 0.0019 18.0 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain Ish1 PF10281.9 KKK15615.1 - 0.05 13.9 0.7 0.18 12.1 0.7 2.0 1 0 0 1 1 1 0 Putative stress-responsive nuclear envelope protein SH3_16 PF18348.1 KKK15615.1 - 0.065 13.0 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 Bacterial dipeptidyl-peptidase Sh3 domain Pkinase PF00069.25 KKK15616.1 - 7e-47 160.0 0.0 9.3e-47 159.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK15616.1 - 3.1e-28 98.8 0.0 4.7e-21 75.2 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 KKK15616.1 - 0.012 15.5 0.1 0.16 11.8 0.0 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KKK15616.1 - 0.033 13.0 0.0 0.06 12.1 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase CENP-N PF05238.13 KKK15628.1 - 3.2e-154 514.2 0.0 3.6e-154 514.1 0.0 1.0 1 0 0 1 1 1 1 Kinetochore protein CHL4 like zf-RING_2 PF13639.6 KKK15629.1 - 1.6e-06 28.3 6.7 2.4e-06 27.8 6.7 1.3 1 0 0 1 1 1 1 Ring finger domain Prok-RING_1 PF14446.6 KKK15629.1 - 0.00011 22.0 4.9 0.00013 21.8 1.7 2.1 1 1 0 2 2 2 1 Prokaryotic RING finger family 1 zf-ANAPC11 PF12861.7 KKK15629.1 - 0.019 15.0 5.6 0.033 14.3 5.6 1.4 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 KKK15629.1 - 0.024 14.6 6.4 0.035 14.1 6.4 1.3 1 0 0 1 1 1 0 zinc-RING finger domain FANCL_C PF11793.8 KKK15629.1 - 0.03 14.5 7.9 0.09 13.0 7.9 1.7 1 1 0 1 1 1 0 FANCL C-terminal domain PHD PF00628.29 KKK15629.1 - 0.034 14.0 6.4 0.099 12.5 6.4 1.8 1 1 0 1 1 1 0 PHD-finger CTU2 PF10288.9 KKK15629.1 - 0.054 13.7 0.7 3 8.1 0.7 2.2 1 1 0 1 1 1 0 Cytoplasmic tRNA 2-thiolation protein 2 zf-RING_11 PF17123.5 KKK15629.1 - 0.13 12.0 3.3 0.25 11.1 3.3 1.6 1 0 0 1 1 1 0 RING-like zinc finger zf-RING_4 PF14570.6 KKK15629.1 - 0.43 10.4 7.0 0.68 9.8 7.0 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Zf_RING PF16744.5 KKK15629.1 - 0.51 10.5 6.9 1 9.6 5.6 2.1 1 1 1 2 2 2 0 KIAA1045 RING finger zf-C3HC4_3 PF13920.6 KKK15629.1 - 0.55 10.1 5.2 0.88 9.5 5.2 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.7 KKK15629.1 - 0.62 10.2 9.3 1.3 9.2 9.3 1.6 1 0 0 1 1 1 0 RING-variant domain zf-RING_UBOX PF13445.6 KKK15629.1 - 0.67 10.0 4.8 1.2 9.2 4.8 1.5 1 0 0 1 1 1 0 RING-type zinc-finger C1_1 PF00130.22 KKK15629.1 - 1.1 9.2 12.9 0.11 12.4 3.6 2.6 2 1 1 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING-like PF08746.11 KKK15629.1 - 1.4 9.3 6.4 9.8 6.6 6.6 2.2 1 1 1 2 2 2 0 RING-like domain bZIP_2 PF07716.15 KKK15630.1 - 1e-12 47.9 11.9 1e-12 47.9 11.9 1.8 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.21 KKK15630.1 - 0.0021 18.1 8.6 0.0054 16.8 8.6 1.7 1 0 0 1 1 1 1 bZIP transcription factor EccE PF11203.8 KKK15630.1 - 0.044 14.1 0.9 0.08 13.3 0.9 1.5 1 0 0 1 1 1 0 Putative type VII ESX secretion system translocon, EccE TSC22 PF01166.18 KKK15630.1 - 0.95 9.8 4.0 0.58 10.5 1.3 2.1 2 0 0 2 2 2 0 TSC-22/dip/bun family Ndc1_Nup PF09531.10 KKK15630.1 - 1.4 7.5 7.4 2.1 7.0 7.4 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Asp PF00026.23 KKK15635.1 - 5.8e-74 249.3 12.6 6.9e-74 249.1 12.6 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KKK15635.1 - 2e-08 34.7 2.9 1.8e-06 28.3 1.9 2.8 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KKK15635.1 - 4.5e-06 27.2 1.8 0.0059 17.2 0.3 3.1 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.6 KKK15635.1 - 0.088 12.6 0.0 0.23 11.2 0.0 1.7 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal Phosphoesterase PF04185.14 KKK15636.1 - 1.7e-79 267.6 1.5 1.7e-79 267.6 1.5 1.4 2 0 0 2 2 2 1 Phosphoesterase family Fascin PF06268.13 KKK15636.1 - 2.2e-05 24.6 1.8 8.4e-05 22.8 0.2 2.2 1 1 1 2 2 2 1 Fascin domain PG_isomerase_N PF18353.1 KKK15636.1 - 0.028 14.8 0.0 0.078 13.4 0.0 1.7 1 0 0 1 1 1 0 Phosphoglucose isomerase N-terminal domain Cytochrom_D1 PF02239.16 KKK15636.1 - 0.12 10.9 0.0 0.18 10.3 0.0 1.2 1 0 0 1 1 1 0 Cytochrome D1 heme domain Sugar_tr PF00083.24 KKK15637.1 - 1.1e-74 252.0 23.4 1.3e-74 251.7 23.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKK15637.1 - 1.2e-17 63.9 40.2 6e-11 41.9 19.5 2.9 1 1 2 3 3 3 3 Major Facilitator Superfamily MFS_1_like PF12832.7 KKK15637.1 - 0.0028 16.6 1.4 0.0028 16.6 1.4 2.5 2 1 0 2 2 2 1 MFS_1 like family DUF3792 PF12670.7 KKK15637.1 - 2.3 8.4 20.1 1.2 9.3 2.4 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF3792) G-patch PF01585.23 KKK15666.1 - 1.8e-05 24.6 0.1 3.6e-05 23.5 0.1 1.5 1 0 0 1 1 1 1 G-patch domain zf-U1 PF06220.12 KKK15666.1 - 0.26 11.1 1.9 14 5.5 0.1 2.5 2 0 0 2 2 2 0 U1 zinc finger adh_short PF00106.25 KKK15667.1 - 1.9e-14 53.6 0.0 6.1e-14 51.9 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 KKK15667.1 - 5.1e-06 26.5 0.0 8.9e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 KKK15667.1 - 1.7e-05 24.5 0.0 3e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.15 KKK15667.1 - 0.043 12.9 0.1 0.062 12.4 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Epimerase PF01370.21 KKK15667.1 - 0.13 11.7 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family SUV3_C PF12513.8 KKK15668.1 - 1.8e-16 59.8 0.1 3.7e-16 58.8 0.1 1.6 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.31 KKK15668.1 - 5.4e-11 42.8 0.0 1.7e-10 41.2 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Suv3_C_1 PF18147.1 KKK15668.1 - 3.1e-06 27.0 0.1 6.8e-06 25.9 0.1 1.6 1 0 0 1 1 1 1 Suv3 C-terminal domain 1 DUF4771 PF15995.5 KKK15668.1 - 0.012 15.9 0.0 0.026 14.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4771) TK PF00265.18 KKK15668.1 - 0.18 11.7 0.0 0.48 10.3 0.0 1.6 2 0 0 2 2 2 0 Thymidine kinase Sec1 PF00995.23 KKK15669.1 - 2.1e-112 377.3 0.0 2.8e-112 376.9 0.0 1.1 1 0 0 1 1 1 1 Sec1 family Glycos_transf_2 PF00535.26 KKK15669.1 - 0.13 12.1 0.5 2.7 7.8 0.0 2.4 2 0 0 2 2 2 0 Glycosyl transferase family 2 DEC-1_N PF04625.13 KKK15669.1 - 7.3 5.5 11.1 5.7 5.8 9.1 1.7 2 0 0 2 2 2 0 DEC-1 protein, N-terminal region CorA PF01544.18 KKK15670.1 - 6e-45 153.8 0.0 8e-45 153.4 0.0 1.1 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein MFS_1 PF07690.16 KKK15671.1 - 1.9e-36 125.7 26.1 1.9e-36 125.7 26.1 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 KKK15671.1 - 6.6e-07 28.9 8.1 6.6e-07 28.9 8.1 2.8 1 1 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB Med17 PF10156.9 KKK15672.1 - 8.4e-100 334.6 0.0 1.2e-99 334.1 0.0 1.1 1 0 0 1 1 1 1 Subunit 17 of Mediator complex DAO PF01266.24 KKK15673.1 - 4.7e-45 154.7 0.3 5.4e-45 154.5 0.3 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KKK15673.1 - 0.001 19.2 0.9 0.0026 17.9 0.9 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 KKK15673.1 - 0.0018 17.6 2.3 1.2 8.3 0.0 3.4 3 1 1 4 4 4 2 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.6 KKK15673.1 - 0.0021 17.4 0.0 0.11 11.7 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KKK15673.1 - 0.0026 17.8 0.1 0.22 11.5 0.1 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 KKK15673.1 - 0.0059 15.9 0.0 0.0089 15.3 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KKK15673.1 - 0.041 13.0 0.6 0.065 12.3 0.6 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.27 KKK15673.1 - 0.063 13.9 0.0 0.27 11.8 0.1 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KKK15673.1 - 0.19 10.9 0.1 0.33 10.2 0.1 1.3 1 0 0 1 1 1 0 Thi4 family Xan_ur_permease PF00860.20 KKK15674.1 - 7.8e-68 228.9 34.1 1.3e-67 228.2 34.1 1.3 1 0 0 1 1 1 1 Permease family MFS_1 PF07690.16 KKK15676.1 - 1.4e-43 149.2 47.2 5.9e-43 147.1 47.1 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KKK15676.1 - 1.4e-11 43.6 26.3 1e-09 37.4 26.3 2.8 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 KKK15676.1 - 0.005 15.2 2.4 0.005 15.2 2.4 2.2 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family Per1 PF04080.13 KKK15676.1 - 0.3 10.8 3.9 1.8 8.3 0.0 2.3 2 0 0 2 2 2 0 Per1-like family PBP PF01161.20 KKK15677.1 - 3.7e-15 56.4 0.2 4.7e-15 56.1 0.2 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Gly_transf_sug PF04488.15 KKK15678.1 - 0.016 15.8 0.0 0.044 14.4 0.0 1.7 1 1 0 1 1 1 0 Glycosyltransferase sugar-binding region containing DXD motif CAP59_mtransfer PF11735.8 KKK15679.1 - 6.1e-74 248.7 0.0 7.8e-74 248.4 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 Helicase_C PF00271.31 KKK15680.1 - 5.4e-17 62.1 0.0 8.1e-17 61.6 0.0 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF3694 PF12473.8 KKK15680.1 - 0.087 13.5 0.1 0.14 12.8 0.1 1.3 1 0 0 1 1 1 0 Kinesin protein Pkinase PF00069.25 KKK15681.1 - 4.2e-55 186.9 0.0 4.8e-55 186.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK15681.1 - 1.6e-29 103.0 0.0 2e-29 102.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KKK15681.1 - 0.00039 19.8 0.0 0.00063 19.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KKK15681.1 - 0.00063 19.2 0.2 0.0011 18.3 0.2 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KKK15681.1 - 0.0015 18.5 0.3 0.0037 17.2 0.2 1.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KKK15681.1 - 0.003 16.4 0.0 0.0043 15.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Seadorna_VP7 PF07387.11 KKK15681.1 - 0.031 13.3 0.1 0.04 13.0 0.1 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Haspin_kinase PF12330.8 KKK15681.1 - 0.071 12.0 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain eRF1_1 PF03463.15 KKK15681.1 - 0.15 12.0 0.0 0.23 11.5 0.0 1.3 1 0 0 1 1 1 0 eRF1 domain 1 Lipocalin_9 PF17186.4 KKK15688.1 - 2.7e-07 30.9 0.0 6.4e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 Lipocalin-like domain CoA_transf_3 PF02515.17 KKK15689.1 - 8.1e-40 137.1 0.4 1.1e-38 133.3 0.0 2.1 2 0 0 2 2 2 2 CoA-transferase family III Aconitase PF00330.20 KKK15690.1 - 6.1e-145 483.8 0.0 7.7e-145 483.4 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KKK15690.1 - 5.4e-39 133.5 0.0 8.3e-39 132.9 0.0 1.3 1 0 0 1 1 1 1 Aconitase C-terminal domain PH_4 PF15404.6 KKK15692.1 - 1.7e-53 181.2 4.9 1.3e-52 178.3 1.0 3.5 3 1 0 3 3 3 1 Pleckstrin homology domain Spo7_2_N PF15407.6 KKK15692.1 - 4.3e-23 80.7 1.2 1.4e-22 79.1 1.2 2.0 1 0 0 1 1 1 1 Sporulation protein family 7 PH PF00169.29 KKK15692.1 - 3.3e-09 37.2 8.9 0.00013 22.5 0.0 6.1 5 1 0 5 5 5 2 PH domain PH_6 PF15406.6 KKK15692.1 - 0.0043 17.3 0.1 5.5 7.3 0.0 2.9 2 0 0 2 2 2 2 Pleckstrin homology domain PH_9 PF15410.6 KKK15692.1 - 0.07 13.5 0.3 0.71 10.2 0.1 2.7 2 0 0 2 2 2 0 Pleckstrin homology domain DUF1992 PF09350.10 KKK15692.1 - 0.16 12.1 1.0 2.1 8.6 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF1992) GLTP PF08718.11 KKK15693.1 - 4.9e-45 153.5 0.0 6.7e-45 153.0 0.0 1.2 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) BMC PF00936.19 KKK15693.1 - 0.057 13.4 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 BMC domain Macro PF01661.21 KKK15694.1 - 6.3e-40 135.9 0.1 9.3e-40 135.4 0.1 1.2 1 0 0 1 1 1 1 Macro domain Peptidase_S24 PF00717.23 KKK15695.1 - 3.9e-05 23.5 0.0 0.00019 21.3 0.0 2.1 1 1 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 KKK15695.1 - 0.0016 18.2 0.0 0.53 10.1 0.0 2.3 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 IQCJ-SCHIP1 PF15157.6 KKK15695.1 - 2 8.2 5.2 3.2 7.6 5.2 1.3 1 0 0 1 1 1 0 Fusion protein IQCJ-SCHIP1 with IQ-like motif IMS PF00817.20 KKK15700.1 - 2.3e-33 115.3 0.0 7.6e-18 64.9 0.0 2.3 1 1 1 2 2 2 2 impB/mucB/samB family zf_UBZ PF18439.1 KKK15700.1 - 4.5e-14 51.7 1.1 9.3e-14 50.7 1.1 1.6 1 0 0 1 1 1 1 Ubiquitin-Binding Zinc Finger IMS_C PF11799.8 KKK15700.1 - 3.6e-12 47.0 0.0 7.7e-12 45.9 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 KKK15700.1 - 0.024 14.9 0.0 0.05 13.9 0.0 1.6 1 0 0 1 1 1 0 IMS family HHH motif DUF765 PF05570.11 KKK15700.1 - 0.078 13.2 1.5 0.14 12.4 0.1 2.0 2 0 0 2 2 2 0 Circovirus protein of unknown function (DUF765) GREB1 PF15782.5 KKK15701.1 - 0.34 8.0 9.4 0.46 7.5 9.4 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Chorion_2 PF03964.15 KKK15701.1 - 1 10.2 12.0 0.23 12.3 3.6 2.9 2 0 0 2 2 2 0 Chorion family 2 Nuc_sug_transp PF04142.15 KKK15702.1 - 2.2e-32 112.5 13.6 2.8e-32 112.2 13.6 1.0 1 0 0 1 1 1 1 Nucleotide-sugar transporter CRT-like PF08627.10 KKK15702.1 - 7e-05 21.9 3.1 7e-05 21.9 3.1 1.7 2 0 0 2 2 2 1 CRT-like, chloroquine-resistance transporter-like EmrE PF13536.6 KKK15702.1 - 0.0013 18.4 0.6 0.0013 18.4 0.6 2.4 1 1 1 2 2 2 1 Putative multidrug resistance efflux transporter EamA PF00892.20 KKK15702.1 - 0.0061 16.7 29.1 0.21 11.8 3.8 3.0 2 1 1 3 3 3 2 EamA-like transporter family ASFV_J13L PF05568.11 KKK15702.1 - 0.29 10.9 2.1 1.6 8.4 0.1 2.6 3 0 0 3 3 3 0 African swine fever virus J13L protein Phage_holin_5_2 PF16079.5 KKK15702.1 - 1.7 9.1 6.0 0.77 10.1 0.2 3.0 3 1 0 3 3 3 0 Phage holin family Hol44, in holin superfamily V MFS_1 PF07690.16 KKK15703.1 - 8.3e-36 123.6 53.8 2.4e-34 118.8 32.0 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2614 PF11023.8 KKK15703.1 - 6.8 6.8 7.7 1.7 8.8 0.3 3.1 3 0 0 3 3 3 0 Zinc-ribbon containing domain VWA_2 PF13519.6 KKK15704.1 - 0.00058 20.5 0.0 0.0017 19.0 0.0 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 KKK15704.1 - 0.036 14.3 0.0 0.15 12.3 0.0 2.0 1 1 0 1 1 1 0 von Willebrand factor type A domain Fungal_trans_2 PF11951.8 KKK15706.1 - 2.3e-11 43.2 0.0 4.3e-11 42.2 0.0 1.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 KKK15710.1 - 0.00075 19.8 4.1 8.4 7.1 0.1 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KKK15710.1 - 0.0089 16.4 1.9 2.9 8.5 0.1 2.7 2 0 0 2 2 2 2 Zinc-finger double domain ATP-synt_D PF01813.17 KKK15711.1 - 2.6e-71 239.5 1.2 3.5e-71 239.1 1.2 1.2 1 0 0 1 1 1 1 ATP synthase subunit D HtrL_YibB PF09612.10 KKK15711.1 - 0.045 13.3 0.1 0.065 12.7 0.1 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (HtrL_YibB) DUF3919 PF13057.6 KKK15711.1 - 0.095 12.3 0.6 0.14 11.8 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3919) CobA_CobO_BtuR PF02572.15 KKK15711.1 - 0.27 11.5 3.5 0.99 9.6 0.1 2.4 2 1 1 3 3 3 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP DUF5446 PF17522.2 KKK15711.1 - 0.47 10.6 2.4 0.85 9.8 0.7 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5446) TPR_14 PF13428.6 KKK15712.1 - 6.6e-12 45.2 19.7 0.78 10.7 0.0 11.7 8 3 5 13 13 13 3 Tetratricopeptide repeat Suf PF05843.14 KKK15712.1 - 6.7e-11 42.7 15.7 0.063 13.2 0.1 6.6 2 2 3 6 6 6 5 Suppressor of forked protein (Suf) TPR_19 PF14559.6 KKK15712.1 - 5e-08 33.4 0.4 2.2 8.9 0.0 5.8 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_15 PF13429.6 KKK15712.1 - 1.3e-07 31.1 7.0 0.00051 19.3 0.2 4.9 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 KKK15712.1 - 1.4e-07 31.2 6.3 0.26 11.6 0.0 7.7 7 1 1 8 8 8 1 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 KKK15712.1 - 1.4e-06 28.3 18.7 0.8 9.7 0.1 7.6 6 2 1 7 7 7 2 Mad3/BUB1 homology region 1 TPR_2 PF07719.17 KKK15712.1 - 5.6e-06 26.1 12.7 0.97 9.7 0.0 7.4 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_12 PF13424.6 KKK15712.1 - 8.8e-06 25.9 6.1 3.4 8.0 0.1 6.9 6 1 0 6 6 6 1 Tetratricopeptide repeat SNAP PF14938.6 KKK15712.1 - 0.0028 17.1 4.5 0.55 9.6 0.4 4.7 5 1 0 5 5 5 1 Soluble NSF attachment protein, SNAP TPR_17 PF13431.6 KKK15712.1 - 0.0055 17.0 4.5 1.6 9.3 0.1 6.2 6 0 0 6 6 6 1 Tetratricopeptide repeat HAT PF02184.16 KKK15712.1 - 0.014 15.4 1.9 2.8 8.0 0.0 5.3 5 0 0 5 5 4 0 HAT (Half-A-TPR) repeat RPN7 PF10602.9 KKK15712.1 - 0.022 14.5 0.3 0.62 9.7 0.1 3.0 3 1 0 3 3 3 0 26S proteasome subunit RPN7 NRDE-2 PF08424.10 KKK15712.1 - 0.051 12.7 19.8 0.049 12.8 0.3 6.5 2 2 3 5 5 5 0 NRDE-2, necessary for RNA interference TPR_1 PF00515.28 KKK15712.1 - 0.097 12.5 0.2 40 4.2 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 KKK15712.1 - 0.81 9.7 8.5 43 4.1 0.3 6.2 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_6 PF13174.6 KKK15712.1 - 7.7 7.4 14.7 20 6.1 0.0 6.8 9 0 0 9 9 6 0 Tetratricopeptide repeat RRM_1 PF00076.22 KKK15713.1 - 5.8e-12 45.3 0.0 8.5e-12 44.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C2H2 PF00096.26 KKK15714.1 - 1.1e-07 31.9 10.4 6.5e-06 26.3 2.8 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KKK15714.1 - 1.8e-05 24.9 2.5 1.8e-05 24.9 2.5 4.0 4 0 0 4 4 4 1 Zinc-finger double domain zf-met PF12874.7 KKK15714.1 - 0.00015 22.0 8.4 0.0006 20.1 0.5 2.6 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 KKK15714.1 - 0.00019 22.0 1.2 0.00019 22.0 1.2 3.2 3 0 0 3 3 3 1 C2H2-type zinc finger DUF2225 PF09986.9 KKK15714.1 - 0.001 18.8 0.1 0.0017 18.1 0.1 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2225) zf-Di19 PF05605.12 KKK15714.1 - 0.0016 18.7 5.8 0.0028 17.9 5.8 1.4 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.8 KKK15714.1 - 0.0077 16.5 0.5 0.0077 16.5 0.5 1.8 2 0 0 2 2 1 1 Zinc-finger double-stranded RNA-binding zf-BED PF02892.15 KKK15714.1 - 0.015 15.3 2.2 0.029 14.4 2.2 1.6 1 0 0 1 1 1 0 BED zinc finger DUF1178 PF06676.11 KKK15714.1 - 0.035 14.5 1.3 0.035 14.5 1.3 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1178) zf-C2H2_6 PF13912.6 KKK15714.1 - 0.036 14.1 2.9 0.059 13.4 0.4 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KKK15714.1 - 0.036 13.8 0.2 0.036 13.8 0.2 3.2 4 0 0 4 4 4 0 C2H2-type zinc-finger domain zf-C2H2_2 PF12756.7 KKK15714.1 - 0.086 13.2 1.9 0.14 12.5 1.9 1.3 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) RGS PF00615.19 KKK15715.1 - 3e-35 121.0 0.1 7e-35 119.8 0.1 1.7 1 0 0 1 1 1 1 Regulator of G protein signaling domain DEP PF00610.21 KKK15715.1 - 4.9e-21 74.6 0.0 8e-18 64.3 0.0 2.5 2 0 0 2 2 2 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) DUF1304 PF06993.12 KKK15715.1 - 0.061 13.3 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1304) CDC73_C PF05179.14 KKK15716.1 - 1.6e-55 187.1 0.0 2.6e-55 186.4 0.0 1.3 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family, C-terminal Glyco_hydro_61 PF03443.14 KKK15717.1 - 8.7e-64 215.2 0.0 1.1e-63 214.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 TRAM_LAG1_CLN8 PF03798.16 KKK15718.1 - 2.1e-44 151.7 23.7 2.1e-44 151.7 23.7 1.9 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.11 KKK15718.1 - 5.5e-18 64.4 0.1 1.4e-17 63.1 0.1 1.7 1 0 0 1 1 1 1 TRAM1-like protein DUF383 PF04063.14 KKK15719.1 - 9.4e-30 103.7 2.0 3.5e-25 88.8 0.0 3.4 2 1 1 3 3 3 2 Domain of unknown function (DUF383) DUF384 PF04064.13 KKK15719.1 - 4.2e-23 81.0 0.8 1.1e-22 79.7 0.8 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF384) TFIIF_alpha PF05793.12 KKK15719.1 - 3.7e-06 25.8 68.0 2.2e-05 23.3 58.5 3.9 1 1 2 3 3 3 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) AsiA PF09010.10 KKK15719.1 - 0.015 15.4 0.0 0.45 10.7 0.0 2.4 2 0 0 2 2 2 0 Anti-Sigma Factor A Histidinol_dh PF00815.20 KKK15720.1 - 6.1e-140 466.8 0.0 7.4e-140 466.6 0.0 1.0 1 0 0 1 1 1 1 Histidinol dehydrogenase FAD_binding_3 PF01494.19 KKK15721.1 - 1.2e-24 87.3 0.0 1.7e-24 86.8 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KKK15721.1 - 4e-08 32.8 1.0 5.9e-05 22.4 0.4 2.1 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KKK15721.1 - 1.7e-07 31.4 0.6 4.3e-07 30.1 0.6 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain ADC PF06314.11 KKK15721.1 - 3e-07 30.3 0.0 8e-07 28.9 0.0 1.8 1 1 0 1 1 1 1 Acetoacetate decarboxylase (ADC) FAD_binding_2 PF00890.24 KKK15721.1 - 1e-05 24.8 0.5 1.7e-05 24.1 0.5 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KKK15721.1 - 0.00018 21.2 2.5 0.00037 20.2 1.4 1.9 1 1 0 2 2 2 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 KKK15721.1 - 0.0003 19.8 0.5 0.011 14.6 0.2 2.6 3 0 0 3 3 3 1 Tryptophan halogenase Pyr_redox PF00070.27 KKK15721.1 - 0.00052 20.5 0.3 0.0048 17.4 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KKK15721.1 - 0.0007 19.1 0.3 0.0012 18.2 0.3 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 KKK15721.1 - 0.0013 18.0 2.2 0.0025 17.1 1.7 1.6 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 KKK15721.1 - 0.0018 17.4 0.1 0.0028 16.8 0.1 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.14 KKK15721.1 - 0.0043 15.8 0.1 0.008 14.9 0.1 1.4 1 0 0 1 1 1 1 HI0933-like protein Amino_oxidase PF01593.24 KKK15721.1 - 0.0088 15.4 0.3 0.65 9.2 0.0 2.3 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.6 KKK15721.1 - 0.019 14.2 0.0 0.047 12.9 0.0 1.6 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KKK15721.1 - 0.077 12.2 0.1 0.13 11.4 0.1 1.3 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.6 KKK15721.1 - 0.23 11.5 0.8 1.1 9.3 0.8 2.1 1 1 0 1 1 1 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 KKK15721.1 - 0.51 9.3 1.3 3.8 6.5 0.1 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein adh_short PF00106.25 KKK15722.1 - 2.1e-23 82.8 0.0 6.1e-17 61.7 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KKK15722.1 - 1.3e-10 41.3 0.0 2.5e-09 37.1 0.0 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KKK15722.1 - 4.1e-09 36.6 0.0 8.5e-09 35.6 0.0 1.5 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KKK15722.1 - 1.2e-05 24.9 0.0 0.00011 21.7 0.0 2.3 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KKK15722.1 - 0.0012 18.1 0.0 0.002 17.3 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Sacchrp_dh_NADP PF03435.18 KKK15722.1 - 0.007 16.6 0.0 1.6 9.0 0.0 2.2 2 0 0 2 2 2 2 Saccharopine dehydrogenase NADP binding domain Glyco_tran_WecB PF03808.13 KKK15722.1 - 0.027 14.4 0.0 8.2 6.3 0.0 2.3 2 0 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family Rad4 PF03835.15 KKK15723.1 - 2.3e-14 53.3 1.8 5.5e-14 52.1 1.8 1.7 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain Transglut_core PF01841.19 KKK15723.1 - 3.5e-13 50.0 1.8 8.5e-13 48.7 1.8 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily DUF2207 PF09972.9 KKK15724.1 - 0.092 11.5 5.9 0.13 11.0 0.4 2.7 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) Microcin PF03526.13 KKK15724.1 - 0.2 11.5 0.9 0.42 10.5 0.3 1.8 2 0 0 2 2 2 0 Colicin E1 (microcin) immunity protein Aldedh PF00171.22 KKK15725.1 - 4.1e-128 427.8 0.0 4.9e-128 427.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 KKK15725.1 - 0.001 18.5 0.1 0.0072 15.8 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1487) LuxC PF05893.14 KKK15725.1 - 0.0014 17.7 0.0 0.0027 16.8 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF4491 PF14898.6 KKK15725.1 - 0.074 13.5 0.0 0.18 12.3 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4491) MoCF_biosynth PF00994.24 KKK15726.1 - 2.5e-39 134.2 0.0 6.5e-22 77.8 0.0 2.3 2 0 0 2 2 2 2 Probable molybdopterin binding domain MoeA_N PF03453.17 KKK15726.1 - 1.1e-36 125.9 2.5 2.3e-36 124.9 2.5 1.5 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.15 KKK15726.1 - 7.5e-17 61.3 0.2 1.9e-16 60.0 0.2 1.8 1 0 0 1 1 1 1 MoeA C-terminal region (domain IV) XPA_C PF05181.12 KKK15727.1 - 1.8e-26 91.8 3.2 3.9e-26 90.8 3.2 1.6 1 0 0 1 1 1 1 XPA protein C-terminus XPA_N PF01286.18 KKK15727.1 - 0.00046 20.2 5.1 0.00046 20.2 5.1 2.1 2 0 0 2 2 2 1 XPA protein N-terminal YhfH PF14149.6 KKK15727.1 - 0.0099 15.8 4.7 0.46 10.5 0.8 2.6 2 0 0 2 2 2 2 YhfH-like protein DUF2235 PF09994.9 KKK15728.1 - 1.3e-71 241.3 0.0 1.7e-71 240.9 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) WD40 PF00400.32 KKK15729.1 - 4e-17 62.3 13.2 0.0003 21.5 0.1 7.0 8 0 0 8 8 8 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKK15729.1 - 3.9e-15 55.9 0.1 1.2e-06 28.7 0.0 5.5 4 1 1 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain HIRA_B PF09453.10 KKK15729.1 - 0.00034 20.4 0.2 0.0011 18.8 0.2 1.9 1 0 0 1 1 1 1 HIRA B motif eIF2A PF08662.11 KKK15729.1 - 0.0014 18.5 0.3 0.07 13.0 0.0 2.8 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KKK15729.1 - 0.09 11.7 0.1 16 4.3 0.0 3.3 2 1 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KKK15729.1 - 0.14 12.2 3.2 13 5.9 0.1 3.9 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Phage_holin_4_2 PF04020.13 KKK15729.1 - 7.8 7.2 10.8 0.86 10.3 3.2 2.3 2 0 0 2 2 2 0 Mycobacterial 4 TMS phage holin, superfamily IV FSH1 PF03959.13 KKK15730.1 - 6.7e-24 84.7 0.0 8.3e-24 84.4 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_1 PF00561.20 KKK15730.1 - 0.0075 15.9 0.6 0.13 11.9 0.4 2.4 1 1 1 2 2 2 1 alpha/beta hydrolase fold adh_short_C2 PF13561.6 KKK15732.1 - 4.6e-43 147.5 0.2 6.5e-43 147.0 0.2 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KKK15732.1 - 1.9e-35 122.1 0.1 3.6e-35 121.2 0.1 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KKK15732.1 - 8.2e-07 29.1 0.4 1.2e-06 28.5 0.4 1.2 1 0 0 1 1 1 1 KR domain UNC-50 PF05216.13 KKK15732.1 - 0.043 13.4 0.0 0.065 12.8 0.0 1.2 1 0 0 1 1 1 0 UNC-50 family F420_oxidored PF03807.17 KKK15732.1 - 0.086 13.4 0.1 0.28 11.8 0.1 2.0 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Cupin_2 PF07883.11 KKK15733.1 - 1.6e-09 37.4 0.0 2.2e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.12 KKK15733.1 - 0.013 15.2 0.0 0.02 14.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Cupin_1 PF00190.22 KKK15733.1 - 0.016 14.8 0.0 0.024 14.3 0.0 1.3 1 0 0 1 1 1 0 Cupin Big_1 PF02369.16 KKK15733.1 - 0.095 12.7 0.1 0.2 11.7 0.0 1.6 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 1) DHHA2 PF02833.14 KKK15734.1 - 1.8e-35 122.2 0.1 2.7e-35 121.6 0.1 1.3 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.20 KKK15734.1 - 9e-08 32.3 0.0 2.1e-07 31.1 0.0 1.7 1 1 0 1 1 1 1 DHH family Rad21_Rec8_N PF04825.13 KKK15735.1 - 4.4e-31 107.3 0.0 8.9e-31 106.3 0.0 1.5 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 KKK15735.1 - 0.02 14.1 0.3 0.049 12.9 0.0 1.8 2 0 0 2 2 2 0 Conserved region of Rad21 / Rec8 like protein adh_short PF00106.25 KKK15736.1 - 8.3e-27 93.9 0.3 1.2e-26 93.4 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KKK15736.1 - 1e-23 84.1 0.0 1.3e-23 83.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KKK15736.1 - 2.5e-05 24.3 0.1 5.4e-05 23.2 0.1 1.6 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KKK15736.1 - 0.0026 17.7 0.1 0.0055 16.6 0.1 1.6 1 1 0 1 1 1 1 NAD(P)H-binding DUF4831 PF16115.5 KKK15736.1 - 0.029 13.4 0.0 0.25 10.4 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4831) DUF5401 PF17380.2 KKK15736.1 - 0.17 9.9 0.0 0.22 9.5 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) DUF1776 PF08643.10 KKK15736.1 - 0.2 11.0 0.0 0.31 10.4 0.0 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Transp_cyt_pur PF02133.15 KKK15737.1 - 5.5e-21 74.9 36.5 8.6e-21 74.2 36.5 1.2 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Myb_DNA-binding PF00249.31 KKK15738.1 - 1e-14 54.4 3.1 2.4e-09 37.2 0.7 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KKK15738.1 - 1.3e-08 34.9 1.6 4.2e-06 26.9 0.2 2.2 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 KKK15738.1 - 0.021 14.7 1.2 0.033 14.1 0.4 1.5 1 1 1 2 2 2 0 Myb DNA-binding like Ribosomal_L34e PF01199.18 KKK15739.1 - 1.1e-43 147.5 1.8 2.1e-43 146.5 1.8 1.5 1 0 0 1 1 1 1 Ribosomal protein L34e Vps36-NZF-N PF16988.5 KKK15739.1 - 0.055 12.9 0.0 0.12 11.8 0.0 1.7 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain PROCN PF08083.11 KKK15740.1 - 8.9e-236 782.2 8.9 8.9e-236 782.2 8.9 2.0 2 0 0 2 2 2 1 PROCN (NUC071) domain PRP8_domainIV PF12134.8 KKK15740.1 - 1.2e-125 417.7 1.3 2.1e-125 416.9 1.3 1.4 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.9 KKK15740.1 - 6.7e-85 282.9 1.9 1.1e-57 194.5 0.3 3.1 2 0 0 2 2 2 2 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.11 KKK15740.1 - 7.9e-80 266.2 2.1 7.9e-80 266.2 2.1 1.9 2 0 0 2 2 2 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.9 KKK15740.1 - 1.3e-71 238.9 0.1 3.6e-71 237.5 0.1 1.8 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 RRM_4 PF10598.9 KKK15740.1 - 1.1e-47 160.3 0.3 3.1e-47 158.8 0.3 1.9 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 PROCT PF08084.11 KKK15740.1 - 7.4e-47 158.3 0.0 2e-46 156.9 0.0 1.8 1 0 0 1 1 1 1 PROCT (NUC072) domain Hom_end_hint PF05203.16 KKK15740.1 - 5.4e-11 42.9 0.1 1.8e-10 41.2 0.0 1.9 2 0 0 2 2 2 1 Hom_end-associated Hint Vint PF14623.6 KKK15740.1 - 0.028 14.2 0.0 0.32 10.8 0.0 2.5 3 0 0 3 3 3 0 Hint-domain Myb_DNA-bind_6 PF13921.6 KKK15741.1 - 6.1e-13 48.8 0.0 5.1e-09 36.2 0.0 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KKK15741.1 - 4.3e-11 42.8 0.1 5.5e-05 23.3 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain HTH_32 PF13565.6 KKK15741.1 - 0.063 13.9 0.1 0.25 12.0 0.0 2.0 1 1 1 2 2 2 0 Homeodomain-like domain SANT_DAMP1_like PF16282.5 KKK15741.1 - 0.2 11.9 0.6 5.1 7.4 0.3 2.2 1 1 1 2 2 2 0 SANT/Myb-like domain of DAMP1 COX5B PF01215.19 KKK15742.1 - 2.8e-54 182.2 0.0 3.6e-54 181.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb Ribosomal_L17 PF01196.19 KKK15743.1 - 3.2e-12 47.2 0.0 6.3e-12 46.2 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L17 Molybdopterin_N PF18364.1 KKK15743.1 - 0.064 13.3 0.1 0.23 11.5 0.0 1.9 2 0 0 2 2 2 0 Molybdopterin oxidoreductase N-terminal domain PIEZO PF15917.5 KKK15743.1 - 0.33 10.4 2.9 0.4 10.1 2.9 1.1 1 0 0 1 1 1 0 Piezo SUZ PF12752.7 KKK15744.1 - 7.6e-17 61.8 2.5 7.6e-17 61.8 2.5 2.7 2 0 0 2 2 2 1 SUZ domain Pmp3 PF01679.17 KKK15745.1 - 1.5e-24 85.9 9.0 1.6e-24 85.8 9.0 1.0 1 0 0 1 1 1 1 Proteolipid membrane potential modulator CFEM PF05730.11 KKK15746.1 - 0.04 14.0 3.9 0.075 13.1 3.9 1.4 1 0 0 1 1 1 0 CFEM domain DAP10 PF07213.11 KKK15746.1 - 0.062 13.3 0.0 0.17 11.9 0.0 1.7 1 0 0 1 1 1 0 DAP10 membrane protein Asp PF00026.23 KKK15747.1 - 6.8e-09 35.6 3.5 1.1e-08 34.8 3.5 1.3 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Podoplanin PF05808.11 KKK15747.1 - 0.01 15.9 0.0 0.022 14.9 0.0 1.4 1 0 0 1 1 1 0 Podoplanin Vpu PF00558.19 KKK15747.1 - 0.011 15.4 0.0 0.019 14.7 0.0 1.3 1 0 0 1 1 1 0 Vpu protein SKG6 PF08693.10 KKK15747.1 - 0.018 14.4 2.6 0.058 12.8 2.6 1.8 1 0 0 1 1 1 0 Transmembrane alpha-helix domain VSP PF03302.13 KKK15747.1 - 0.042 12.7 0.4 0.042 12.7 0.4 2.0 2 0 0 2 2 2 0 Giardia variant-specific surface protein DUF4328 PF14219.6 KKK15747.1 - 0.12 11.9 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4328) OpuAC PF04069.12 KKK15748.1 - 0.074 12.6 0.1 0.15 11.6 0.1 1.4 1 0 0 1 1 1 0 Substrate binding domain of ABC-type glycine betaine transport system Hydrolase_6 PF13344.6 KKK15749.1 - 7.3e-22 77.4 0.0 1.4e-21 76.5 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KKK15749.1 - 6.9e-13 48.5 0.0 1.9e-11 43.9 0.0 3.0 4 0 0 4 4 4 1 HAD-hyrolase-like Hydrolase PF00702.26 KKK15749.1 - 0.15 12.3 0.0 16 5.7 0.0 2.8 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase DUF676 PF05057.14 KKK15750.1 - 7.5e-48 162.9 0.0 1.1e-47 162.4 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 KKK15750.1 - 1e-06 29.5 0.1 1.8e-06 28.8 0.1 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 KKK15750.1 - 0.00042 20.1 0.0 0.00091 19.0 0.0 1.5 1 1 0 1 1 1 1 PGAP1-like protein Palm_thioest PF02089.15 KKK15750.1 - 0.0051 16.7 0.0 0.0085 16.0 0.0 1.3 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Lipase_3 PF01764.25 KKK15750.1 - 0.026 14.4 0.0 0.054 13.4 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) LCAT PF02450.15 KKK15750.1 - 0.026 13.7 0.0 0.042 13.0 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DUF915 PF06028.11 KKK15750.1 - 0.14 11.4 0.0 6.6 6.0 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Ribosomal_L22e PF01776.17 KKK15751.1 - 3.1e-47 159.5 0.4 3.9e-47 159.1 0.4 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family AlgF PF11182.8 KKK15751.1 - 0.034 13.9 0.0 0.069 12.9 0.0 1.5 2 0 0 2 2 2 0 Alginate O-acetyl transferase AlgF Meth_synt_2 PF01717.18 KKK15752.1 - 4.6e-17 62.3 0.0 2.3e-16 60.0 0.0 1.9 1 1 0 1 1 1 1 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 KKK15752.1 - 0.022 14.3 0.0 0.049 13.1 0.0 1.6 2 0 0 2 2 2 0 Cobalamin-independent synthase, N-terminal domain DUF1713 PF08213.11 KKK15753.1 - 8.7e-11 41.6 20.6 1.6e-10 40.7 20.6 1.5 1 0 0 1 1 1 1 Mitochondrial domain of unknown function (DUF1713) Pet20 PF08692.10 KKK15753.1 - 0.0042 17.8 0.3 0.014 16.1 0.0 2.1 2 1 0 2 2 2 1 Mitochondrial protein Pet20 TMEM171 PF15471.6 KKK15753.1 - 3.8 6.4 5.6 1.1 8.2 2.0 1.8 1 1 1 2 2 2 0 Transmembrane protein family 171 G-alpha PF00503.20 KKK15754.1 - 2.5e-106 355.8 0.2 3e-106 355.6 0.2 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KKK15754.1 - 5.3e-14 52.1 0.5 2.3e-09 36.9 0.0 2.8 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KKK15754.1 - 1.2e-07 31.4 0.1 0.0009 18.7 0.1 2.2 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 KKK15754.1 - 0.0048 17.1 0.0 1.1 9.5 0.0 2.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 KKK15754.1 - 0.005 16.9 0.0 3.5 7.7 0.0 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase TniB PF05621.11 KKK15754.1 - 0.026 14.0 0.0 0.05 13.0 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein AAA_29 PF13555.6 KKK15754.1 - 0.078 12.7 0.1 0.16 11.7 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.6 KKK15754.1 - 0.17 11.5 0.0 0.34 10.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain ATP-synt_C PF00137.21 KKK15756.1 - 4.7e-36 122.9 34.6 4.6e-22 78.1 15.3 2.1 2 0 0 2 2 2 2 ATP synthase subunit C Presenilin PF01080.17 KKK15770.1 - 3.4 6.3 10.1 3.6 6.2 10.1 1.1 1 0 0 1 1 1 0 Presenilin Apt1 PF10351.9 KKK15770.1 - 6.9 5.4 15.1 8.2 5.1 15.1 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain MPM1 PF17234.2 KKK15775.1 - 0.064 13.5 0.1 0.064 13.5 0.1 2.2 2 0 0 2 2 2 0 Mitochondrial peculiar membrane protein 1 CN_hydrolase PF00795.22 KKK15776.1 - 9.4e-44 149.7 0.0 1.5e-43 149.1 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.17 KKK15776.1 - 3.1e-23 82.2 0.0 1.6e-22 79.8 0.0 2.0 1 1 0 1 1 1 1 NAD synthase Asn_synthase PF00733.21 KKK15776.1 - 0.14 11.8 0.0 0.31 10.7 0.0 1.5 1 0 0 1 1 1 0 Asparagine synthase NUDIX-like PF09296.11 KKK15777.1 - 8.9e-19 68.0 0.0 2.3e-18 66.7 0.0 1.7 2 0 0 2 2 2 1 NADH pyrophosphatase-like rudimentary NUDIX domain NUDIX PF00293.28 KKK15777.1 - 2.4e-17 63.2 0.1 4.3e-17 62.4 0.1 1.3 1 0 0 1 1 1 1 NUDIX domain zf-NADH-PPase PF09297.11 KKK15777.1 - 0.0078 15.8 2.1 0.015 14.9 2.1 1.4 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain V-SNARE_C PF12352.8 KKK15777.1 - 0.055 13.8 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 Snare region anchored in the vesicle membrane C-terminus DUF3991 PF13154.6 KKK15777.1 - 0.062 13.7 0.0 6.6 7.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3991) POT1 PF02765.17 KKK15778.1 - 6.3e-16 58.5 0.0 1.1e-15 57.8 0.0 1.4 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 HDA2-3 PF11496.8 KKK15779.1 - 8.7e-58 195.8 0.0 1.9e-57 194.7 0.0 1.6 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 FMO-like PF00743.19 KKK15779.1 - 4.8e-32 111.1 0.0 2.6e-22 78.9 0.0 2.1 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KKK15779.1 - 4e-10 39.5 0.0 8.9e-09 35.0 0.0 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KKK15779.1 - 4.5e-07 29.4 0.0 1.1e-06 28.1 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KKK15779.1 - 6.3e-06 25.6 0.9 1.4e-05 24.4 0.0 2.0 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) GAS PF13851.6 KKK15779.1 - 0.0034 16.8 33.3 0.01 15.2 7.0 2.5 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding ArAE_2_N PF10337.9 KKK15779.1 - 0.62 9.0 3.6 1.2 8.1 3.6 1.4 1 0 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal Sec20 PF03908.13 KKK15779.1 - 3.4 7.6 7.2 13 5.8 2.9 3.0 1 1 1 2 2 2 0 Sec20 SAT PF16073.5 KKK15780.1 - 6.9e-84 281.3 4.1 2.5e-82 276.2 0.1 3.1 3 0 0 3 3 3 2 Starter unit:ACP transacylase in aflatoxin biosynthesis ketoacyl-synt PF00109.26 KKK15780.1 - 1.2e-81 274.0 0.0 9.5e-81 271.1 0.0 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 KKK15780.1 - 1.1e-48 166.4 1.6 2.4e-47 162.0 0.0 3.0 3 0 0 3 3 3 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KKK15780.1 - 8.6e-36 122.5 0.4 3.4e-35 120.6 0.4 2.1 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.25 KKK15780.1 - 2e-26 92.1 4.8 2.1e-13 50.4 0.5 2.6 2 0 0 2 2 2 2 Phosphopantetheine attachment site Thioesterase PF00975.20 KKK15780.1 - 1.8e-23 83.9 0.0 4.6e-23 82.5 0.0 1.7 1 0 0 1 1 1 1 Thioesterase domain PS-DH PF14765.6 KKK15780.1 - 1.3e-14 54.2 0.0 2.3e-14 53.3 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Abhydrolase_6 PF12697.7 KKK15780.1 - 5e-08 33.8 8.3 1.8e-07 32.0 1.0 3.4 3 0 0 3 3 3 1 Alpha/beta hydrolase family Thiolase_N PF00108.23 KKK15780.1 - 1.7e-05 24.4 0.0 8.5e-05 22.0 0.0 2.0 2 0 0 2 2 2 1 Thiolase, N-terminal domain KAsynt_C_assoc PF16197.5 KKK15780.1 - 5.2e-05 23.7 0.0 0.00014 22.2 0.0 1.8 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Cu-oxidase_3 PF07732.15 KKK15781.1 - 6.7e-40 135.8 1.4 2.5e-39 134.0 1.4 2.1 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 KKK15781.1 - 5.7e-29 100.6 8.6 6.7e-23 80.9 0.2 3.8 3 2 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 KKK15781.1 - 1.4e-21 77.2 0.0 4.2e-19 69.2 0.0 2.8 2 1 0 2 2 2 2 Multicopper oxidase SH3_2 PF07653.17 KKK15782.1 - 1.2e-09 37.6 0.1 2.2e-09 36.9 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KKK15782.1 - 5.1e-07 29.2 0.0 8e-07 28.6 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KKK15782.1 - 0.00039 20.2 0.1 0.0007 19.4 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain Ferric_reduct PF01794.19 KKK15783.1 - 2.6e-24 85.7 9.7 6.4e-24 84.5 9.7 1.7 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KKK15783.1 - 8.9e-13 48.3 0.0 4.9e-08 33.0 0.0 2.4 2 0 0 2 2 2 2 FAD-binding domain NAD_binding_6 PF08030.12 KKK15783.1 - 0.0042 17.2 0.0 0.32 11.1 0.0 3.0 2 1 1 3 3 3 1 Ferric reductase NAD binding domain bZIP_2 PF07716.15 KKK15784.1 - 0.00011 22.1 11.0 0.00019 21.4 11.0 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 KKK15784.1 - 0.0021 18.6 9.3 0.0028 18.1 9.3 1.2 1 0 0 1 1 1 1 bZIP Maf transcription factor bZIP_1 PF00170.21 KKK15784.1 - 0.016 15.3 11.5 0.024 14.7 11.5 1.3 1 0 0 1 1 1 0 bZIP transcription factor Takusan PF04822.13 KKK15784.1 - 0.034 14.0 2.0 0.035 14.0 0.7 1.7 2 0 0 2 2 2 0 Takusan WD40_alt PF14077.6 KKK15784.1 - 0.083 12.8 0.2 0.2 11.6 0.1 1.7 1 1 0 1 1 1 0 Alternative WD40 repeat motif DivIC PF04977.15 KKK15784.1 - 0.46 10.3 4.5 0.17 11.6 1.3 1.8 1 1 1 2 2 2 0 Septum formation initiator ABC2_membrane PF01061.24 KKK15785.1 - 1.2e-19 70.6 10.6 1.2e-19 70.6 10.6 2.0 2 0 0 2 2 2 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 KKK15785.1 - 0.0008 18.6 10.0 0.0011 18.2 10.0 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein PDR_CDR PF06422.12 KKK15785.1 - 0.011 15.7 0.6 0.011 15.7 0.6 2.1 2 0 0 2 2 2 0 CDR ABC transporter DUF5090 PF17009.5 KKK15785.1 - 0.56 10.1 2.7 1.3 9.0 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5090) Phage_holin_3_6 PF07332.11 KKK15785.1 - 2.9 8.0 8.9 4.1 7.5 5.4 2.1 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III Fungal_trans PF04082.18 KKK15787.1 - 4.6e-13 48.8 0.0 8.3e-13 48.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK15787.1 - 0.015 15.4 1.0 0.015 15.4 1.0 1.9 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain MerR-DNA-bind PF09278.11 KKK15787.1 - 0.074 13.6 0.9 0.26 11.9 0.1 2.3 2 0 0 2 2 2 0 MerR, DNA binding Aida_N PF08910.10 KKK15787.1 - 0.12 12.8 0.0 4.6 7.7 0.0 2.5 2 0 0 2 2 2 0 Aida N-terminus Retrotran_gag_2 PF14223.6 KKK15787.1 - 0.17 11.5 0.4 0.57 9.8 0.0 2.0 3 0 0 3 3 3 0 gag-polypeptide of LTR copia-type ABC_tran_CTD PF16326.5 KKK15787.1 - 0.21 11.9 3.0 12 6.2 0.2 2.7 2 0 0 2 2 2 0 ABC transporter C-terminal domain adh_short_C2 PF13561.6 KKK15788.1 - 5.5e-38 130.8 0.1 8.3e-38 130.3 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KKK15788.1 - 7.8e-35 120.1 0.1 1.3e-34 119.3 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase Fungal_trans PF04082.18 KKK15788.1 - 1.9e-11 43.5 0.0 5.8e-10 38.6 0.0 2.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain KR PF08659.10 KKK15788.1 - 7.4e-05 22.7 0.0 0.00014 21.8 0.0 1.4 1 0 0 1 1 1 1 KR domain PNTB PF02233.16 KKK15792.1 - 4.6e-176 586.3 23.1 4.6e-176 586.3 23.1 2.1 2 0 0 2 2 2 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.21 KKK15792.1 - 2.9e-74 249.0 1.3 5.1e-74 248.2 0.1 2.1 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.15 KKK15792.1 - 3.4e-45 153.7 0.0 7.9e-45 152.5 0.0 1.7 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain PNTB_4TM PF12769.7 KKK15792.1 - 4.3e-20 72.0 7.2 4.3e-20 72.0 7.2 5.9 4 3 2 6 6 6 1 4TM region of pyridine nucleotide transhydrogenase, mitoch 2-Hacid_dh_C PF02826.19 KKK15792.1 - 5e-05 22.7 0.1 0.22 10.9 0.0 2.7 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TPP_enzyme_M PF00205.22 KKK15792.1 - 0.015 15.0 0.4 0.12 12.2 0.4 2.4 1 1 0 1 1 1 0 Thiamine pyrophosphate enzyme, central domain ADH_zinc_N PF00107.26 KKK15792.1 - 0.02 14.9 0.1 0.11 12.5 0.1 2.3 1 1 0 1 1 1 0 Zinc-binding dehydrogenase Pyr_redox_2 PF07992.14 KKK15792.1 - 0.031 13.5 0.1 0.085 12.1 0.1 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FtsJ PF01728.19 KKK15792.1 - 0.076 13.1 0.0 76 3.4 0.0 3.5 2 1 1 3 3 3 0 FtsJ-like methyltransferase CP_ATPgrasp_1 PF04174.13 KKK15792.1 - 0.11 11.5 0.3 1.2 8.1 0.0 2.2 2 0 0 2 2 2 0 A circularly permuted ATPgrasp GIDA PF01134.22 KKK15792.1 - 0.13 11.3 0.9 0.25 10.4 0.9 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A Fungal_trans_2 PF11951.8 KKK15793.1 - 4.3e-36 124.5 0.1 5.5e-36 124.2 0.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK15793.1 - 8.1e-09 35.5 8.2 1.4e-08 34.7 8.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AA_permease_2 PF13520.6 KKK15794.1 - 2.2e-22 79.5 45.7 5.4e-20 71.6 35.1 2.0 2 0 0 2 2 2 2 Amino acid permease AA_permease PF00324.21 KKK15794.1 - 3.3e-08 32.6 25.1 3.3e-08 32.6 25.1 1.6 2 0 0 2 2 2 1 Amino acid permease Fungal_trans PF04082.18 KKK15795.1 - 2.4e-09 36.6 0.2 2.5e-08 33.3 0.0 2.5 3 1 0 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK15795.1 - 4.9e-09 36.2 13.3 9e-09 35.3 13.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short_C2 PF13561.6 KKK15796.1 - 9.5e-64 215.2 0.0 1.2e-63 214.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KKK15796.1 - 2.1e-50 170.9 0.0 2.7e-50 170.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KKK15796.1 - 1.4e-06 28.3 0.0 6.1e-06 26.3 0.0 1.8 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KKK15796.1 - 5.4e-05 22.8 0.0 9.1e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family AdoHcyase_NAD PF00670.21 KKK15796.1 - 0.11 12.6 0.1 0.22 11.6 0.1 1.5 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Methyltransf_32 PF13679.6 KKK15797.1 - 1.7e-23 83.4 0.2 5.7e-23 81.6 0.2 1.8 1 1 0 1 1 1 1 Methyltransferase domain Syntaxin-6_N PF09177.11 KKK15799.1 - 6.4e-26 90.8 0.2 2.5e-25 88.9 0.0 1.9 2 0 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.19 KKK15799.1 - 0.042 13.8 2.2 0.065 13.2 0.5 2.2 2 0 0 2 2 2 0 SNARE domain DUF4713 PF15831.5 KKK15799.1 - 0.044 14.2 1.8 0.17 12.4 1.8 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4713) DUF4795 PF16043.5 KKK15799.1 - 0.11 12.0 2.0 0.79 9.3 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) HMMR_N PF15905.5 KKK15799.1 - 0.54 9.7 3.2 0.42 10.0 0.1 1.9 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal DUF1515 PF07439.11 KKK15799.1 - 5.9 7.0 6.3 50 4.0 0.1 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1515) NAP PF00956.18 KKK15800.1 - 2.5e-29 102.3 15.8 6.3e-28 97.7 11.1 2.4 2 1 1 3 3 3 2 Nucleosome assembly protein (NAP) Med8 PF10232.9 KKK15800.1 - 0.12 11.9 0.1 0.12 11.9 0.1 2.6 3 1 1 4 4 4 0 Mediator of RNA polymerase II transcription complex subunit 8 NmrA PF05368.13 KKK15801.1 - 6.9e-74 248.3 0.0 8.6e-74 248.0 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family PTR2 PF00854.21 KKK15802.1 - 1.9e-93 313.4 5.6 1.9e-93 313.4 5.6 1.9 2 1 0 2 2 2 1 POT family Maf1 PF09174.10 KKK15803.1 - 5.7e-63 212.2 0.0 9.5e-63 211.5 0.0 1.4 1 0 0 1 1 1 1 Maf1 regulator Clat_adaptor_s PF01217.20 KKK15803.1 - 2.2e-33 115.2 0.2 3.6e-33 114.5 0.2 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Phage_GP20 PF06810.11 KKK15804.1 - 0.00097 19.0 8.0 0.00097 19.0 8.0 5.2 3 1 2 5 5 5 1 Phage minor structural protein GP20 Filament PF00038.21 KKK15804.1 - 0.0013 18.3 31.3 0.0013 18.3 31.3 4.0 3 1 0 3 3 3 2 Intermediate filament protein GAS PF13851.6 KKK15804.1 - 0.0019 17.6 11.1 0.0019 17.6 11.1 4.9 3 1 1 4 4 4 2 Growth-arrest specific micro-tubule binding TMEM192 PF14802.6 KKK15804.1 - 0.21 10.7 0.5 3.2 6.8 0.0 2.6 2 0 0 2 2 2 0 TMEM192 family APG17 PF04108.12 KKK15804.1 - 0.43 9.6 26.3 0.13 11.4 5.4 2.7 1 1 0 2 2 2 0 Autophagy protein Apg17 Herpes_UL6 PF01763.16 KKK15804.1 - 5.5 5.4 21.1 6.9 5.1 0.7 2.9 2 1 0 2 2 2 0 Herpesvirus UL6 like Pkinase_fungal PF17667.1 KKK15805.1 - 7.8e-110 367.4 0.0 4.3e-106 355.1 0.0 2.1 1 1 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KKK15805.1 - 0.062 13.2 0.1 1.3 8.9 0.0 2.5 2 0 0 2 2 2 0 Phosphotransferase enzyme family COPIIcoated_ERV PF07970.12 KKK15806.1 - 3.9e-23 82.5 0.0 4.8e-23 82.2 0.0 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter Fungal_trans_2 PF11951.8 KKK15809.1 - 2.8e-09 36.3 0.7 3.7e-09 35.9 0.7 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Tcf25 PF04910.14 KKK15812.1 - 3.7e-75 253.2 0.0 4.9e-75 252.8 0.0 1.1 1 0 0 1 1 1 1 Transcriptional repressor TCF25 TPR_12 PF13424.6 KKK15812.1 - 0.0032 17.7 1.0 0.15 12.4 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 KKK15812.1 - 0.023 14.8 1.1 0.065 13.4 0.2 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 KKK15812.1 - 0.034 15.0 0.2 0.71 10.9 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF3246 PF11596.8 KKK15812.1 - 2.2 7.7 4.6 3.1 7.2 4.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) SR-25 PF10500.9 KKK15812.1 - 3.6 7.1 10.0 0.46 10.0 5.8 1.6 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein PP2C PF00481.21 KKK15813.1 - 1.3e-45 156.1 0.0 2.4e-45 155.2 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 KKK15813.1 - 4.9e-06 26.3 0.0 1e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 KKK15813.1 - 9.3e-05 22.4 0.1 0.31 10.9 0.0 2.8 3 0 0 3 3 3 2 Stage II sporulation protein E (SpoIIE) PQ-loop PF04193.14 KKK15814.1 - 5.2e-40 135.0 6.6 3.7e-21 74.6 0.2 2.5 2 0 0 2 2 2 2 PQ loop repeat ER_lumen_recept PF00810.18 KKK15814.1 - 0.044 14.6 0.0 0.8 10.5 0.0 2.3 2 0 0 2 2 2 0 ER lumen protein retaining receptor FTR1 PF03239.14 KKK15814.1 - 1.7 7.7 5.5 2.2 7.4 2.8 2.1 2 0 0 2 2 2 0 Iron permease FTR1 family DUF1187 PF06688.11 KKK15815.1 - 0.12 12.7 0.1 0.25 11.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1187) Ribosomal_L27A PF00828.19 KKK15829.1 - 2.4e-30 105.8 2.0 4.3e-30 105.0 2.0 1.4 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A GntR PF00392.21 KKK15829.1 - 0.11 12.1 0.1 0.57 9.9 0.0 2.0 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family Cyclin PF08613.11 KKK15830.1 - 3.1e-14 53.6 0.0 4.8e-14 53.0 0.0 1.3 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 KKK15830.1 - 0.00045 20.0 0.0 0.00073 19.3 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Pal1 PF08316.11 KKK15831.1 - 4.6e-46 157.0 0.6 1.1e-45 155.7 0.6 1.7 1 0 0 1 1 1 1 Pal1 cell morphology protein CDC45 PF02724.14 KKK15831.1 - 1.7 6.8 5.5 2.4 6.4 5.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Beta_elim_lyase PF01212.21 KKK15843.1 - 2.5e-34 118.9 0.0 3.4e-34 118.5 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Fungal_trans PF04082.18 KKK15843.1 - 1.2e-06 27.7 0.1 1.9e-06 27.1 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Aminotran_5 PF00266.19 KKK15843.1 - 0.00014 20.9 0.0 0.00022 20.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Zn_clus PF00172.18 KKK15843.1 - 0.00048 20.2 8.0 0.00093 19.3 8.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aminotran_1_2 PF00155.21 KKK15843.1 - 0.00068 18.9 0.0 0.001 18.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Met_gamma_lyase PF06838.11 KKK15843.1 - 0.013 14.0 0.1 0.019 13.5 0.1 1.1 1 0 0 1 1 1 0 Methionine gamma-lyase tRNA-synt_1c PF00749.21 KKK15844.1 - 2.5e-91 305.9 0.0 3.2e-91 305.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain FAD_binding_4 PF01565.23 KKK15845.1 - 2e-22 79.5 2.6 3.5e-22 78.6 2.6 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KKK15845.1 - 1.8e-06 28.0 0.1 3.6e-06 27.0 0.1 1.6 1 0 0 1 1 1 1 Berberine and berberine like PseudoU_synth_2 PF00849.22 KKK15846.1 - 3.7e-26 92.1 0.0 5.5e-26 91.6 0.0 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.25 KKK15846.1 - 0.0023 17.6 0.1 0.0052 16.5 0.1 1.6 1 0 0 1 1 1 1 S4 domain GFA PF04828.14 KKK15846.1 - 0.15 12.4 0.0 0.3 11.4 0.0 1.5 1 0 0 1 1 1 0 Glutathione-dependent formaldehyde-activating enzyme 4HBT PF03061.22 KKK15848.1 - 2.1e-13 50.4 0.0 2.8e-13 50.0 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_2 PF13279.6 KKK15848.1 - 0.0001 22.8 0.0 0.00014 22.4 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl-ACP_TE PF01643.17 KKK15848.1 - 0.00046 19.6 0.3 0.00068 19.0 0.3 1.2 1 0 0 1 1 1 1 Acyl-ACP thioesterase ILVD_EDD PF00920.21 KKK15849.1 - 8.3e-153 509.7 0.0 1e-152 509.4 0.0 1.1 1 0 0 1 1 1 1 Dehydratase family DnaJ_C PF01556.18 KKK15849.1 - 1.4e-37 129.0 0.2 2.6e-37 128.2 0.2 1.4 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KKK15849.1 - 6.8e-22 77.4 1.3 2.4e-21 75.6 1.6 1.8 2 0 0 2 2 2 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KKK15849.1 - 2.3e-13 50.3 16.6 7.8e-13 48.6 16.6 2.0 1 0 0 1 1 1 1 DnaJ central domain zf-RING_10 PF16685.5 KKK15849.1 - 0.27 11.4 5.4 0.88 9.8 0.4 2.5 2 0 0 2 2 2 0 zinc RING finger of MSL2 DUF1356 PF07092.12 KKK15849.1 - 0.53 9.5 4.6 3.4 6.9 0.4 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1356) RseC_MucC PF04246.12 KKK15849.1 - 0.61 10.0 3.9 0.25 11.3 0.2 2.2 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC SHOCT PF09851.9 KKK15849.1 - 1.1 9.1 7.2 2.2 8.1 0.1 3.1 3 0 0 3 3 3 0 Short C-terminal domain Mito_carr PF00153.27 KKK15851.1 - 1.3e-29 102.0 1.7 1.7e-15 56.7 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Atg8 PF02991.16 KKK15852.1 - 3.3e-47 158.9 1.0 5e-47 158.4 0.6 1.4 2 0 0 2 2 2 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 KKK15852.1 - 7e-05 23.2 0.1 0.00011 22.5 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 DUF5305 PF17231.2 KKK15852.1 - 0.016 14.7 0.0 0.023 14.1 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5305) Coprogen_oxidas PF01218.18 KKK15853.1 - 2.5e-135 449.9 0.0 3.4e-135 449.5 0.0 1.2 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase Acyl_transf_1 PF00698.21 KKK15868.1 - 7.5e-49 166.9 0.0 1.1e-48 166.4 0.0 1.2 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KKK15868.1 - 1.2e-25 89.8 0.2 2.9e-25 88.6 0.2 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 KKK15868.1 - 2.3e-17 63.5 0.0 4.4e-17 62.6 0.0 1.5 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension PS-DH PF14765.6 KKK15868.1 - 1e-06 28.3 0.4 2e-06 27.2 0.4 1.6 1 0 0 1 1 1 1 Polyketide synthase dehydratase Catalase PF00199.19 KKK15876.1 - 8.6e-164 545.2 0.1 1.1e-163 544.9 0.1 1.1 1 0 0 1 1 1 1 Catalase Catalase_C PF18011.1 KKK15876.1 - 2.3e-49 167.0 0.0 3.5e-49 166.4 0.0 1.3 1 0 0 1 1 1 1 C-terminal domain found in long catalases Catalase-rel PF06628.12 KKK15876.1 - 9e-16 57.9 0.0 1.9e-15 56.8 0.0 1.6 1 0 0 1 1 1 1 Catalase-related immune-responsive Pro_dh PF01619.18 KKK15877.1 - 3.6e-62 210.6 0.0 5.1e-62 210.1 0.0 1.2 1 0 0 1 1 1 1 Proline dehydrogenase AAA_assoc PF14363.6 KKK15877.1 - 0.024 15.0 0.0 0.051 13.9 0.0 1.6 1 0 0 1 1 1 0 Domain associated at C-terminal with AAA Glyco_hydro_65N PF03636.15 KKK15878.1 - 3.4e-32 111.9 0.0 5.5e-32 111.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Glyco_hydro_65m PF03632.15 KKK15878.1 - 7.4e-25 87.6 4.9 1.9e-19 69.8 0.7 2.3 1 1 1 2 2 2 2 Glycosyl hydrolase family 65 central catalytic domain Glyco_hydro_65C PF03633.15 KKK15878.1 - 0.00081 19.3 0.2 0.0026 17.6 0.2 1.9 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, C-terminal domain Kin17_mid PF10357.9 KKK15880.1 - 1.1e-49 167.5 2.8 1.1e-49 167.5 2.8 1.9 2 0 0 2 2 2 1 Domain of Kin17 curved DNA-binding protein zf-C2H2_jaz PF12171.8 KKK15880.1 - 0.0004 20.6 1.1 0.00086 19.5 1.1 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KKK15880.1 - 0.0013 19.1 3.9 0.0018 18.6 2.3 2.1 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 KKK15880.1 - 0.51 10.7 5.8 0.17 12.2 0.8 2.4 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) AC_N PF16214.5 KKK15880.1 - 0.88 8.6 4.5 1.3 8.1 4.5 1.2 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region Actin PF00022.19 KKK15881.1 - 8.9e-24 83.8 0.0 1.2e-18 67.0 0.0 3.1 3 0 0 3 3 3 3 Actin Actin_micro PF17003.5 KKK15881.1 - 0.21 10.7 0.0 0.35 10.0 0.0 1.2 1 0 0 1 1 1 0 Putative actin-like family TT_ORF2 PF02957.15 KKK15881.1 - 0.24 12.3 11.2 0.22 12.5 0.5 2.9 2 0 0 2 2 2 0 TT viral ORF2 CBFD_NFYB_HMF PF00808.23 KKK15882.1 - 1.4e-17 63.7 0.2 2.5e-17 62.9 0.2 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KKK15882.1 - 1e-07 32.3 1.7 2.3e-07 31.2 0.0 1.9 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.13 KKK15882.1 - 0.0075 16.2 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated DUF5333 PF17267.2 KKK15882.1 - 0.063 13.5 0.4 0.084 13.1 0.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5333) YolD PF08863.10 KKK15882.1 - 0.57 10.3 8.3 0.32 11.1 6.4 1.5 2 0 0 2 2 2 0 YolD-like protein adh_short PF00106.25 KKK15883.1 - 8.8e-43 146.0 0.0 1e-42 145.8 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KKK15883.1 - 1.8e-29 103.0 0.0 2.2e-29 102.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KKK15883.1 - 3.6e-10 40.1 0.2 5.5e-10 39.4 0.2 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KKK15883.1 - 0.00072 19.5 0.0 0.0012 18.8 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KKK15883.1 - 0.0018 17.8 0.0 0.02 14.4 0.0 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 KKK15883.1 - 0.027 14.5 0.0 0.043 13.9 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 KKK15883.1 - 0.066 13.8 0.0 0.15 12.7 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DAO PF01266.24 KKK15884.1 - 3.9e-31 108.9 0.1 1.5e-30 107.0 0.1 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KKK15884.1 - 0.071 13.3 0.0 0.18 12.1 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KKK15884.1 - 0.084 13.4 0.0 1.4 9.6 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase SMC_Nse1 PF07574.13 KKK15885.1 - 8.5e-67 224.8 0.0 1.6e-66 224.0 0.0 1.5 1 0 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.11 KKK15885.1 - 8.2e-12 45.2 10.1 8.2e-12 45.2 10.1 1.9 2 0 0 2 2 2 1 RING-like domain zf-CCCH PF00642.24 KKK15885.1 - 6.2e-07 29.2 20.0 1e-06 28.5 2.5 2.9 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_1 PF00076.22 KKK15885.1 - 0.0022 17.8 0.0 0.0058 16.4 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf_CCCH_4 PF18345.1 KKK15885.1 - 0.018 15.1 3.3 0.018 15.1 3.3 3.3 3 0 0 3 3 3 0 Zinc finger domain DUF4796 PF16044.5 KKK15885.1 - 0.024 14.3 0.1 0.049 13.2 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4796) Torus PF16131.5 KKK15885.1 - 0.078 13.7 2.9 1.8 9.3 0.3 2.7 2 0 0 2 2 2 0 Torus domain EGF PF00008.27 KKK15891.1 - 0.67 10.3 5.8 1.6 9.1 5.8 1.7 1 0 0 1 1 1 0 EGF-like domain ATP-sulfurylase PF01747.17 KKK15892.1 - 1.8e-86 289.0 0.0 2.7e-86 288.4 0.0 1.3 1 0 0 1 1 1 1 ATP-sulfurylase APS_kinase PF01583.20 KKK15892.1 - 3.4e-60 202.5 0.0 5.5e-60 201.8 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase PUA_2 PF14306.6 KKK15892.1 - 5.3e-51 172.4 0.0 8.8e-51 171.7 0.0 1.4 1 0 0 1 1 1 1 PUA-like domain TPR_12 PF13424.6 KKK15892.1 - 0.11 12.8 0.3 2.5 8.5 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat AAA_18 PF13238.6 KKK15892.1 - 0.16 12.5 0.0 0.54 10.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain Complex1_LYR PF05347.15 KKK15893.1 - 7.4e-16 57.9 5.1 7.4e-16 57.9 5.1 1.9 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KKK15893.1 - 0.082 13.7 2.4 0.22 12.3 2.4 1.7 1 0 0 1 1 1 0 Complex1_LYR-like ALMT PF11744.8 KKK15894.1 - 0.35 9.6 1.2 0.46 9.3 1.2 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter HLH PF00010.26 KKK15895.1 - 5.7e-16 58.2 1.1 1.5e-15 56.9 0.8 1.8 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Fzo_mitofusin PF04799.13 KKK15895.1 - 0.35 10.4 1.8 0.57 9.7 1.8 1.2 1 0 0 1 1 1 0 fzo-like conserved region Glyco_hydro_16 PF00722.21 KKK15922.1 - 1.4e-43 148.5 1.6 1.4e-43 148.5 1.6 2.6 2 1 0 2 2 2 1 Glycosyl hydrolases family 16 Hira PF07569.11 KKK15922.1 - 0.17 11.6 5.6 0.3 10.8 5.6 1.3 1 0 0 1 1 1 0 TUP1-like enhancer of split DUF2981 PF11200.8 KKK15922.1 - 6.1 6.5 7.1 9.2 5.9 7.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) tRNA-synt_2b PF00587.25 KKK15923.1 - 1.5e-33 116.3 0.0 2.6e-33 115.5 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Fungal_trans PF04082.18 KKK15923.1 - 1.5e-25 89.7 1.0 2.6e-25 89.0 1.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain HGTP_anticodon PF03129.20 KKK15923.1 - 0.00012 22.2 0.0 0.00024 21.2 0.0 1.4 1 0 0 1 1 1 1 Anticodon binding domain DUF3439 PF11921.8 KKK15923.1 - 2.4 8.2 6.6 6.2 6.8 6.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Sugar_tr PF00083.24 KKK15924.1 - 1.2e-70 238.6 13.8 1.2e-66 225.5 7.8 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KKK15924.1 - 1.1e-18 67.3 17.5 1.1e-18 67.3 17.5 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Cyt-b5 PF00173.28 KKK15925.1 - 2.6e-10 40.3 0.0 3.8e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain His_Phos_2 PF00328.22 KKK15926.1 - 3e-09 36.7 0.0 1.2e-08 34.7 0.0 1.8 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Gtr1_RagA PF04670.12 KKK15927.1 - 5.3e-69 232.1 0.2 9e-69 231.3 0.1 1.4 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region Arf PF00025.21 KKK15927.1 - 0.00017 21.1 0.0 0.00038 20.0 0.0 1.5 1 1 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KKK15927.1 - 0.0083 16.3 0.0 0.017 15.3 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 KKK15927.1 - 0.015 15.4 0.0 0.044 13.9 0.0 1.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase SRPRB PF09439.10 KKK15927.1 - 0.044 13.2 0.0 0.086 12.3 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 KKK15927.1 - 0.083 13.3 0.0 0.16 12.4 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_14 PF13173.6 KKK15927.1 - 0.14 12.2 0.0 0.39 10.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain FA_hydroxylase PF04116.13 KKK15928.1 - 2.6e-24 86.1 14.8 2.6e-24 86.1 14.8 2.2 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Lactamase_B_4 PF13691.6 KKK15929.1 - 1.2e-24 85.7 0.1 4.9e-24 83.8 0.1 2.1 2 0 0 2 2 2 1 tRNase Z endonuclease Lactamase_B_2 PF12706.7 KKK15929.1 - 6.4e-10 38.9 0.0 4e-05 23.2 0.0 2.7 3 0 0 3 3 3 2 Beta-lactamase superfamily domain bZIP_1 PF00170.21 KKK15929.1 - 2.1e-08 34.1 10.0 5.4e-08 32.8 10.0 1.7 1 0 0 1 1 1 1 bZIP transcription factor Lactamase_B PF00753.27 KKK15929.1 - 0.00012 22.1 0.0 0.00041 20.4 0.0 1.9 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily bZIP_2 PF07716.15 KKK15929.1 - 0.00074 19.6 10.1 0.00074 19.6 10.1 2.9 3 0 0 3 3 3 1 Basic region leucine zipper Phage_HK97_TLTM PF06120.11 KKK15929.1 - 0.49 9.5 5.0 0.95 8.6 5.0 1.4 1 0 0 1 1 1 0 Tail length tape measure protein GGACT PF06094.12 KKK15930.1 - 2.6e-13 50.6 0.0 4e-13 50.0 0.0 1.3 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like ABC_tran PF00005.27 KKK15931.1 - 3.1e-40 137.9 5.1 4e-20 72.7 0.0 3.8 3 1 0 3 3 2 2 ABC transporter AAA_21 PF13304.6 KKK15931.1 - 1.4e-10 41.5 6.4 0.0017 18.2 0.0 4.4 3 1 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KKK15931.1 - 1.5e-09 37.6 4.1 0.016 14.6 0.0 4.3 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain ABC_tran_Xtn PF12848.7 KKK15931.1 - 1.9e-09 37.4 2.6 1.9e-09 37.4 2.6 2.3 2 0 0 2 2 2 1 ABC transporter AAA_23 PF13476.6 KKK15931.1 - 9.9e-07 29.5 7.4 0.00098 19.7 6.5 2.9 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KKK15931.1 - 2.6e-06 27.1 0.7 0.0034 17.1 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 KKK15931.1 - 5.3e-05 23.3 0.4 0.11 12.5 0.0 3.2 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_30 PF13604.6 KKK15931.1 - 0.0004 20.2 0.1 0.68 9.6 0.0 2.8 2 1 0 2 2 2 2 AAA domain MeaB PF03308.16 KKK15931.1 - 0.00042 19.4 0.4 0.18 10.7 0.0 2.3 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_28 PF13521.6 KKK15931.1 - 0.00063 20.0 0.0 0.22 11.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 KKK15931.1 - 0.00074 19.9 0.0 1.2 9.6 0.0 3.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 KKK15931.1 - 0.00075 20.1 0.1 1.3 9.5 0.1 2.9 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KKK15931.1 - 0.00084 19.8 0.2 2.1 8.7 0.0 2.9 2 1 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 KKK15931.1 - 0.0012 18.8 0.1 2.4 8.0 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase AAA_33 PF13671.6 KKK15931.1 - 0.0016 18.6 0.7 2.5 8.3 0.0 3.6 4 0 0 4 4 3 1 AAA domain AAA_5 PF07728.14 KKK15931.1 - 0.0016 18.5 0.8 0.37 10.8 0.0 3.4 3 1 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KKK15931.1 - 0.0021 18.3 4.8 0.18 12.0 0.0 3.9 2 2 0 3 3 3 1 AAA domain RNA_helicase PF00910.22 KKK15931.1 - 0.0035 17.7 0.1 1.1 9.6 0.0 2.5 2 0 0 2 2 2 1 RNA helicase AAA_27 PF13514.6 KKK15931.1 - 0.006 16.2 1.3 0.027 14.1 0.0 2.5 3 0 0 3 3 3 1 AAA domain NTPase_1 PF03266.15 KKK15931.1 - 0.0068 16.3 1.4 18 5.2 0.0 3.7 3 1 0 3 3 3 0 NTPase AAA_14 PF13173.6 KKK15931.1 - 0.011 15.8 0.1 5.6 7.0 0.0 3.4 4 0 0 4 4 3 0 AAA domain AAA_25 PF13481.6 KKK15931.1 - 0.013 15.1 0.7 3.2 7.3 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_7 PF12775.7 KKK15931.1 - 0.015 14.8 0.0 0.21 11.1 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_13 PF13166.6 KKK15931.1 - 0.022 13.4 8.1 0.091 11.4 0.6 2.6 3 0 0 3 3 3 0 AAA domain NACHT PF05729.12 KKK15931.1 - 0.025 14.5 0.4 1.4 8.8 0.0 2.5 2 0 0 2 2 2 0 NACHT domain Lipase_GDSL_3 PF14606.6 KKK15931.1 - 0.1 12.7 0.7 0.39 10.8 0.0 2.3 2 1 1 3 3 3 0 GDSL-like Lipase/Acylhydrolase family AAA_15 PF13175.6 KKK15931.1 - 0.29 10.8 11.4 0.44 10.2 0.0 3.5 4 0 0 4 4 4 0 AAA ATPase domain AAA_24 PF13479.6 KKK15931.1 - 0.38 10.5 2.4 5.3 6.7 0.0 2.8 3 0 0 3 3 3 0 AAA domain Viral_helicase1 PF01443.18 KKK15931.1 - 0.41 10.4 1.8 17 5.0 0.1 3.2 2 1 0 2 2 2 0 Viral (Superfamily 1) RNA helicase DUF87 PF01935.17 KKK15931.1 - 1.9 8.6 5.0 3.4 7.7 0.0 3.0 3 0 0 3 3 3 0 Helicase HerA, central domain TrkH PF02386.16 KKK15932.1 - 5.1e-76 256.1 5.8 9.1e-53 179.4 0.1 2.7 2 1 1 3 3 3 2 Cation transport protein DUF4436 PF14494.6 KKK15932.1 - 0.34 10.2 1.4 0.57 9.4 1.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4436) MoaC PF01967.21 KKK15933.1 - 1.4e-45 154.7 0.2 2.3e-45 154.0 0.2 1.4 1 0 0 1 1 1 1 MoaC family Mob_synth_C PF06463.13 KKK15933.1 - 2.6e-38 130.8 0.0 4.2e-37 126.9 0.0 2.4 2 0 0 2 2 2 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.21 KKK15933.1 - 2.3e-26 93.2 0.0 3.9e-26 92.4 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 KKK15933.1 - 7.8e-05 23.0 0.0 0.00021 21.6 0.0 1.7 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 KKK15933.1 - 0.078 13.1 0.2 0.5 10.5 0.0 2.4 2 1 0 2 2 2 0 4Fe-4S single cluster domain Syntaxin-6_N PF09177.11 KKK15934.1 - 0.036 14.6 0.7 0.68 10.5 0.1 2.7 2 0 0 2 2 2 0 Syntaxin 6, N-terminal Baculo_PEP_C PF04513.12 KKK15934.1 - 0.055 13.5 0.4 11 6.0 0.0 2.4 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DASH_Dad2 PF08654.10 KKK15934.1 - 0.059 13.8 0.3 3.2 8.2 0.0 2.7 2 0 0 2 2 2 0 DASH complex subunit Dad2 Methyltransf_15 PF09445.10 KKK15934.1 - 0.092 12.3 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase NPV_P10 PF05531.12 KKK15934.1 - 0.54 10.8 3.1 3.8 8.0 0.5 3.2 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein YjbE PF11106.8 KKK15935.1 - 0.12 12.6 5.9 0.16 12.2 5.9 1.3 1 0 0 1 1 1 0 Exopolysaccharide production protein YjbE ADH_N PF08240.12 KKK15936.1 - 1.2e-27 95.9 1.2 2.2e-27 95.1 1.2 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KKK15936.1 - 6.8e-14 52.0 0.0 1e-13 51.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KKK15936.1 - 3.9e-05 23.2 1.5 0.046 13.2 0.9 3.2 2 1 0 2 2 2 2 Glucose dehydrogenase C-terminus DEAD PF00270.29 KKK15937.1 - 1.7e-25 89.8 0.0 9.4e-25 87.4 0.0 2.1 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KKK15937.1 - 9.1e-24 83.9 0.0 3e-23 82.3 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KKK15937.1 - 1.4e-05 25.1 0.1 0.00012 22.1 0.0 2.4 2 1 1 3 3 3 1 Type III restriction enzyme, res subunit ATP-synt_G PF04718.15 KKK15938.1 - 1.1e-36 125.6 0.1 1.2e-36 125.5 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial ATP synthase g subunit Methyltransf_16 PF10294.9 KKK15939.1 - 9e-21 74.4 0.0 1.8e-20 73.4 0.0 1.4 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_25 PF13649.6 KKK15939.1 - 0.04 14.6 0.0 0.15 12.8 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain VPS28 PF03997.12 KKK15941.1 - 3e-73 245.5 0.0 3.6e-73 245.3 0.0 1.1 1 0 0 1 1 1 1 VPS28 protein Glyco_hydro_31 PF01055.26 KKK15942.1 - 2.3e-158 528.0 2.2 2.9e-158 527.7 2.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 KKK15942.1 - 4.7e-34 117.0 0.0 8.7e-34 116.2 0.0 1.4 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 KKK15942.1 - 3.9e-14 52.7 2.5 3.9e-14 52.7 2.5 2.1 2 0 0 2 2 2 1 Galactose mutarotase-like Amidohydro_2 PF04909.14 KKK15943.1 - 3.2e-28 99.3 0.0 4e-28 99.0 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase Noc2 PF03715.13 KKK15944.1 - 1.4e-113 379.1 0.5 1.7e-69 234.4 0.1 2.7 1 1 1 2 2 2 2 Noc2p family Nop14 PF04147.12 KKK15944.1 - 0.74 8.0 0.0 0.74 8.0 0.0 3.4 2 1 0 3 3 3 0 Nop14-like family tRNA-synt_2b PF00587.25 KKK15969.1 - 1.9e-38 132.2 0.0 3.5e-38 131.4 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 KKK15969.1 - 8.1e-17 61.4 5.1 8.1e-17 61.4 5.1 1.9 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain Atg14 PF10186.9 KKK15969.1 - 3.2 6.8 6.3 1.9 7.5 4.6 1.4 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Ras PF00071.22 KKK15970.1 - 1.4e-38 132.0 0.6 1.8e-37 128.4 0.6 1.9 1 1 0 1 1 1 1 Ras family Roc PF08477.13 KKK15970.1 - 2.8e-14 53.4 0.1 7.9e-14 51.9 0.1 1.7 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKK15970.1 - 3.3e-05 23.4 0.0 0.0018 17.8 0.0 2.0 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KKK15970.1 - 9.1e-05 22.5 0.0 0.00012 22.2 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 KKK15970.1 - 0.0021 17.5 0.0 0.0071 15.8 0.0 1.7 1 1 1 2 2 2 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 KKK15970.1 - 0.0049 16.4 0.3 0.24 10.9 0.1 2.6 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_28 PF13521.6 KKK15970.1 - 0.012 15.8 0.0 0.02 15.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KKK15970.1 - 0.016 15.2 0.0 0.02 14.9 0.0 1.5 1 1 0 1 1 1 0 AAA domain FeoB_N PF02421.18 KKK15970.1 - 0.07 12.7 0.0 1.2 8.6 0.0 2.0 2 0 0 2 2 2 0 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KKK15970.1 - 0.15 12.0 0.0 11 5.9 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase NAGLU_N PF12971.7 KKK15970.1 - 0.16 11.8 0.1 0.41 10.4 0.1 1.7 1 0 0 1 1 1 0 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain TniB PF05621.11 KKK15970.1 - 0.18 11.2 0.0 0.35 10.2 0.0 1.5 2 0 0 2 2 2 0 Bacterial TniB protein ACT PF01842.25 KKK15971.1 - 1.1e-05 25.0 0.0 1.3e-05 24.8 0.0 1.1 1 0 0 1 1 1 1 ACT domain 2-Hacid_dh_C PF02826.19 KKK15972.1 - 2.2e-52 177.0 0.0 3.1e-52 176.5 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KKK15972.1 - 3.6e-35 120.5 0.0 4.3e-35 120.3 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KKK15972.1 - 1e-05 25.7 0.1 3e-05 24.3 0.1 1.7 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.21 KKK15972.1 - 0.00063 19.8 0.0 0.0019 18.3 0.0 1.8 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain IlvN PF07991.12 KKK15972.1 - 0.0041 16.7 0.1 0.19 11.3 0.0 2.3 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain XdhC_C PF13478.6 KKK15972.1 - 0.021 15.3 0.0 0.061 13.8 0.0 1.7 2 0 0 2 2 2 0 XdhC Rossmann domain 3HCDH_N PF02737.18 KKK15972.1 - 0.11 12.4 0.2 1.2 9.0 0.4 2.1 1 1 1 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Ribosomal_S3Ae PF01015.18 KKK15973.1 - 3.5e-88 294.5 3.3 4.8e-88 294.0 3.3 1.2 1 0 0 1 1 1 1 Ribosomal S3Ae family SUI1 PF01253.22 KKK15973.1 - 0.0092 16.5 0.1 0.1 13.1 0.0 2.3 2 0 0 2 2 2 1 Translation initiation factor SUI1 Abhydro_lipase PF04083.16 KKK15973.1 - 0.14 11.7 0.0 0.29 10.7 0.0 1.5 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region NEMO PF11577.8 KKK15973.1 - 0.15 12.1 0.5 0.83 9.7 0.0 2.2 2 0 0 2 2 2 0 NF-kappa-B essential modulator NEMO WAPL PF07814.13 KKK15974.1 - 4.7e-71 239.5 0.0 7.3e-71 238.9 0.0 1.3 1 0 0 1 1 1 1 Wings apart-like protein regulation of heterochromatin Wap1 PF16997.5 KKK15974.1 - 0.072 12.2 0.0 1.3 8.1 0.1 2.4 2 0 0 2 2 2 0 Wap1 domain UPRTase PF14681.6 KKK15975.1 - 1.5e-67 227.1 0.0 1.7e-67 226.9 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 KKK15975.1 - 0.0024 17.4 0.0 0.0034 16.9 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Flu_C_NS1 PF03506.13 KKK15975.1 - 0.21 11.6 0.3 0.35 10.8 0.3 1.3 1 0 0 1 1 1 0 Influenza C non-structural protein (NS1) Pkinase PF00069.25 KKK15976.1 - 3.6e-62 210.1 0.0 4.3e-62 209.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK15976.1 - 4.8e-24 85.0 0.0 6.4e-24 84.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase E1-E2_ATPase PF00122.20 KKK15977.1 - 5.1e-32 110.9 0.3 2.3e-31 108.7 0.0 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 KKK15977.1 - 5.4e-10 39.9 0.2 0.00017 22.0 0.0 3.2 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.21 KKK15977.1 - 7.4e-08 32.3 5.5 7.4e-08 32.3 5.5 2.2 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus P5-ATPase PF12409.8 KKK15977.1 - 1.7e-05 24.9 0.5 4.8e-05 23.5 0.3 1.9 2 0 0 2 2 2 1 P5-type ATPase cation transporter Cation_ATPase_N PF00690.26 KKK15977.1 - 0.0018 18.0 0.2 0.0077 15.9 0.0 2.1 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Fungal_trans PF04082.18 KKK15978.1 - 2.7e-11 43.0 0.0 5.9e-11 41.9 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK15978.1 - 1.4e-08 34.7 12.5 2.4e-08 33.9 12.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FlxA PF14282.6 KKK15978.1 - 0.036 14.0 1.5 0.085 12.8 1.5 1.5 1 0 0 1 1 1 0 FlxA-like protein ELO PF01151.18 KKK15979.1 - 1.6e-59 201.4 19.6 2e-59 201.1 19.6 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family DHHC PF01529.20 KKK15979.1 - 8.9 6.4 16.5 3.2 7.9 0.2 3.1 2 1 1 3 3 3 0 DHHC palmitoyltransferase COesterase PF00135.28 KKK15980.1 - 4.2e-85 286.6 0.0 1.1e-84 285.1 0.0 1.5 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KKK15980.1 - 3.2e-11 43.5 0.4 1.3e-10 41.6 0.4 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KKK15980.1 - 0.0058 16.1 0.1 0.0098 15.4 0.1 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Clr5 PF14420.6 KKK15981.1 - 1.1e-12 48.0 1.2 1.7e-12 47.4 1.2 1.3 1 0 0 1 1 1 1 Clr5 domain THOC7 PF05615.13 KKK15981.1 - 0.15 12.3 0.9 0.58 10.4 0.4 2.0 1 1 1 2 2 2 0 Tho complex subunit 7 p450 PF00067.22 KKK15983.1 - 2.9e-58 197.7 0.0 3.7e-58 197.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DAGAT PF03982.13 KKK15984.1 - 3.4e-49 167.4 0.1 5.2e-49 166.8 0.1 1.3 1 0 0 1 1 1 1 Diacylglycerol acyltransferase UDPGT PF00201.18 KKK15984.1 - 6.2e-10 38.5 0.0 8.7e-10 38.0 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 KKK15984.1 - 0.0073 16.3 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain RVT_1 PF00078.27 KKK15985.1 - 0.0052 16.3 0.0 0.013 15.1 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) ABC_membrane PF00664.23 KKK15986.1 - 5.9e-93 311.5 32.4 5.5e-49 167.3 13.5 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KKK15986.1 - 1.1e-71 239.7 0.0 9.1e-36 123.4 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KKK15986.1 - 3.3e-14 52.9 0.0 5e-05 22.8 0.1 3.9 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 KKK15986.1 - 1.1e-08 34.3 2.3 0.00079 18.3 0.1 2.8 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_29 PF13555.6 KKK15986.1 - 4.5e-07 29.5 0.3 0.0029 17.3 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 KKK15986.1 - 4.9e-07 30.3 1.7 0.0088 16.4 0.0 3.3 2 1 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 KKK15986.1 - 7.6e-07 29.2 0.1 0.034 14.0 0.0 3.3 3 0 0 3 3 3 2 RsgA GTPase AAA_15 PF13175.6 KKK15986.1 - 9.7e-07 28.8 0.0 0.016 14.9 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 KKK15986.1 - 4.8e-05 23.7 1.5 0.2 11.9 0.1 3.9 2 2 0 2 2 2 2 AAA domain AAA_21 PF13304.6 KKK15986.1 - 0.00013 21.9 3.0 0.29 10.9 0.2 3.9 3 1 1 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 KKK15986.1 - 0.00015 21.9 4.4 0.44 10.8 0.4 4.4 3 2 0 3 3 3 2 Putative exonuclease SbcCD, C subunit AAA_28 PF13521.6 KKK15986.1 - 0.00066 20.0 0.1 0.13 12.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 KKK15986.1 - 0.00081 19.9 0.7 0.22 12.0 0.1 2.9 3 0 0 3 3 3 1 AAA domain SRP54 PF00448.22 KKK15986.1 - 0.0011 18.7 0.0 2.1 7.9 0.0 2.9 2 0 0 2 2 2 2 SRP54-type protein, GTPase domain AAA_33 PF13671.6 KKK15986.1 - 0.0022 18.2 0.0 2.5 8.2 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KKK15986.1 - 0.0031 17.1 3.9 0.44 10.1 0.0 3.9 4 0 0 4 4 4 1 AAA domain AAA_7 PF12775.7 KKK15986.1 - 0.005 16.4 0.0 2.5 7.6 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_30 PF13604.6 KKK15986.1 - 0.0065 16.2 5.9 0.52 10.0 0.3 3.9 4 1 0 4 4 3 1 AAA domain Rad17 PF03215.15 KKK15986.1 - 0.007 16.3 0.1 0.55 10.1 0.0 2.4 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_5 PF07728.14 KKK15986.1 - 0.0074 16.3 0.1 11 6.0 0.0 3.9 3 1 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 KKK15986.1 - 0.0081 16.7 0.6 4.9 7.7 0.2 2.9 2 1 1 3 3 3 1 AAA domain G-alpha PF00503.20 KKK15986.1 - 0.0097 15.1 0.0 3 6.9 0.0 2.5 2 1 0 2 2 2 1 G-protein alpha subunit DUF87 PF01935.17 KKK15986.1 - 0.018 15.1 0.3 4.5 7.3 0.1 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain MMR_HSR1 PF01926.23 KKK15986.1 - 0.025 14.6 0.0 7.5 6.7 0.0 3.0 2 0 0 2 2 2 0 50S ribosome-binding GTPase Zeta_toxin PF06414.12 KKK15986.1 - 0.028 13.7 0.0 5 6.4 0.0 2.6 2 0 0 2 2 2 0 Zeta toxin PRK PF00485.18 KKK15986.1 - 0.053 13.3 0.1 2.3 7.9 0.0 2.6 3 0 0 3 3 2 0 Phosphoribulokinase / Uridine kinase family RNA_helicase PF00910.22 KKK15986.1 - 0.069 13.5 0.1 12 6.3 0.0 2.8 2 0 0 2 2 2 0 RNA helicase Mg_chelatase PF01078.21 KKK15986.1 - 0.094 12.1 0.0 3.7 6.9 0.0 2.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI APS_kinase PF01583.20 KKK15986.1 - 0.1 12.5 0.0 5.6 6.8 0.0 2.8 2 0 0 2 2 2 0 Adenylylsulphate kinase Tyrosinase PF00264.20 KKK15987.1 - 6e-30 105.2 9.3 9.1e-30 104.6 9.3 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase Glyco_hydro_7 PF00840.20 KKK15988.1 - 3.1e-113 378.8 17.8 2.4e-72 244.0 13.1 2.9 2 1 1 3 3 3 2 Glycosyl hydrolase family 7 CBM_1 PF00734.18 KKK15988.1 - 1.6e-13 50.3 12.2 1.6e-13 50.3 12.2 3.9 5 0 0 5 5 5 1 Fungal cellulose binding domain Toxin_7 PF05980.12 KKK15988.1 - 5 7.5 10.8 0.082 13.2 2.6 2.3 3 0 0 3 3 3 0 Toxin 7 Fer4_10 PF13237.6 KKK15988.1 - 9.7 6.4 10.1 4.3 7.5 0.0 3.5 3 0 0 3 3 3 0 4Fe-4S dicluster domain ATP-grasp_3 PF02655.14 KKK15990.1 - 1.3e-08 35.0 0.0 4.1e-08 33.4 0.0 1.8 1 1 0 1 1 1 1 ATP-grasp domain Glyco_hydro_16 PF00722.21 KKK15992.1 - 1.9e-07 30.8 0.0 3.8e-07 29.7 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 NIP_1 PF08995.10 KKK15992.1 - 0.034 14.5 0.8 0.079 13.4 0.8 1.6 1 0 0 1 1 1 0 Necrosis inducing protein-1 DPPIV_N PF00930.21 KKK15993.1 - 1.6e-17 63.3 0.5 1.6e-15 56.8 0.0 2.0 1 1 1 2 2 2 2 Dipeptidyl peptidase IV (DPP IV) N-terminal region DPPIV_N PF00930.21 KKK15994.1 - 3.5e-06 26.0 0.1 8.1e-06 24.8 0.0 1.6 2 0 0 2 2 2 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Abhydrolase_3 PF07859.13 KKK15995.1 - 2.4e-23 83.1 0.0 3.4e-23 82.6 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KKK15995.1 - 1.3e-18 67.0 0.0 1.8e-18 66.5 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 KKK15995.1 - 0.0023 17.4 0.0 1.5 8.3 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Glyco_transf_54 PF04666.13 KKK15995.1 - 0.062 12.2 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region Pro-kuma_activ PF09286.11 KKK15996.1 - 1.6e-41 142.0 0.0 3e-41 141.0 0.0 1.5 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain AMP-binding PF00501.28 KKK16009.1 - 6e-75 252.4 0.0 8e-75 252.0 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KKK16009.1 - 4.9e-19 69.1 0.1 1.1e-18 68.0 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Aminotran_1_2 PF00155.21 KKK16010.1 - 1.5e-61 208.6 0.0 1.8e-61 208.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 KKK16010.1 - 0.0017 17.7 0.0 0.0023 17.2 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 KKK16010.1 - 0.027 13.4 0.0 0.04 12.9 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 KKK16010.1 - 0.055 12.8 0.0 0.14 11.4 0.0 1.7 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Ribosomal_L13 PF00572.18 KKK16011.1 - 4.7e-12 46.2 0.0 4.3e-10 39.9 0.0 2.3 1 1 0 1 1 1 1 Ribosomal protein L13 DnaJ PF00226.31 KKK16012.1 - 1.3e-21 76.4 0.9 1.3e-21 76.4 0.9 2.0 2 0 0 2 2 2 1 DnaJ domain Kinesin PF00225.23 KKK16013.1 - 2.8e-113 378.2 0.0 2.8e-113 378.2 0.0 2.1 3 0 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 KKK16013.1 - 4.4e-25 88.4 0.0 1.5e-24 86.6 0.0 1.9 2 0 0 2 2 2 1 Microtubule binding DUF2458 PF10454.9 KKK16013.1 - 0.084 12.5 15.3 0.57 9.8 1.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2458) Pterin_bind PF00809.22 KKK16013.1 - 2 8.0 5.5 7.5 6.1 0.3 2.2 2 0 0 2 2 2 0 Pterin binding enzyme MukB PF04310.12 KKK16013.1 - 2.2 8.1 5.4 24 4.7 1.7 2.7 3 0 0 3 3 3 0 MukB N-terminal FUSC PF04632.12 KKK16013.1 - 3.4 6.1 13.2 1.6 7.2 9.8 1.8 2 0 0 2 2 2 0 Fusaric acid resistance protein family Tau95 PF09734.9 KKK16013.1 - 6.8 7.5 6.1 1.1 10.1 1.7 1.9 2 0 0 2 2 2 0 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain IF-2B PF01008.17 KKK16014.1 - 5e-75 252.3 0.0 6.3e-75 252.0 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family DUF1275 PF06912.11 KKK16015.1 - 2.1e-47 161.6 10.9 2.4e-47 161.3 10.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) DUF3040 PF11239.8 KKK16015.1 - 0.027 14.7 2.1 0.34 11.2 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3040) Pol_alpha_B_N PF08418.10 KKK16017.1 - 1e-70 238.5 0.0 1.8e-70 237.7 0.0 1.4 2 0 0 2 2 2 1 DNA polymerase alpha subunit B N-terminal DNA_pol_E_B PF04042.16 KKK16017.1 - 1.6e-37 128.9 0.0 2.3e-37 128.4 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B zf-C2H2 PF00096.26 KKK16022.1 - 5.7e-09 36.0 10.9 6.1e-06 26.4 0.6 3.0 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KKK16022.1 - 4e-08 33.3 10.7 8.1e-06 26.0 2.7 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KKK16022.1 - 4.4e-06 27.1 8.9 0.00049 20.7 0.6 3.1 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KKK16022.1 - 5.9e-05 22.7 7.4 0.0093 15.7 0.2 2.8 2 0 0 2 2 2 2 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 KKK16022.1 - 0.0013 19.0 4.1 0.018 15.3 0.1 2.3 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KKK16022.1 - 0.0082 16.1 5.8 0.92 9.6 0.3 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2HE PF16278.5 KKK16022.1 - 0.058 13.9 8.8 1.6 9.3 1.0 2.3 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-AN1 PF01428.16 KKK16022.1 - 7.8 6.8 8.8 30 4.9 2.1 2.6 1 1 1 2 2 2 0 AN1-like Zinc finger DLH PF01738.18 KKK16024.1 - 1.2e-08 34.8 0.0 3.6e-08 33.2 0.0 1.8 1 1 0 1 1 1 1 Dienelactone hydrolase family Tubulin PF00091.25 KKK16025.1 - 1.7e-66 224.2 0.0 2.3e-66 223.8 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KKK16025.1 - 5.2e-46 155.9 0.0 8.3e-46 155.3 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 KKK16025.1 - 0.00041 20.1 0.0 0.0008 19.1 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Vps8 PF12816.7 KKK16026.1 - 5.4e-63 212.1 0.2 1.2e-62 210.9 0.1 1.7 2 0 0 2 2 2 1 Golgi CORVET complex core vacuolar protein 8 Glyco_hydro_16 PF00722.21 KKK16026.1 - 1.1e-08 34.8 0.0 2.5e-08 33.6 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 Clathrin PF00637.20 KKK16026.1 - 1e-05 25.4 0.0 0.2 11.5 0.0 3.0 3 0 0 3 3 3 2 Region in Clathrin and VPS zf-C3H2C3 PF17122.5 KKK16026.1 - 0.00045 20.2 0.3 0.0013 18.7 0.3 1.8 1 0 0 1 1 1 1 Zinc-finger Pox_D3 PF04580.13 KKK16026.1 - 0.037 13.7 0.0 0.068 12.8 0.0 1.3 1 0 0 1 1 1 0 Chordopoxvirinae D3 protein zf-C3HC4_2 PF13923.6 KKK16026.1 - 0.63 9.9 1.9 1.1 9.1 0.1 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KKK16026.1 - 0.95 9.5 3.9 0.22 11.5 0.3 1.8 2 0 0 2 2 2 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 KKK16026.1 - 1.3 9.1 5.0 0.48 10.5 0.1 2.4 2 0 0 2 2 2 0 RING-type zinc-finger zf-RING_2 PF13639.6 KKK16026.1 - 1.5 9.2 6.7 0.1 13.0 1.1 2.1 2 0 0 2 2 2 0 Ring finger domain DEAD PF00270.29 KKK16027.1 - 2.1e-16 60.2 0.0 5e-16 59.0 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KKK16027.1 - 7.8e-09 35.9 0.0 2.9e-08 34.0 0.0 2.1 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KKK16027.1 - 1.9e-08 34.5 0.0 3.4e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HTH_45 PF14947.6 KKK16027.1 - 8.5e-05 22.5 0.1 0.00032 20.6 0.1 2.0 2 0 0 2 2 2 1 Winged helix-turn-helix AAA_22 PF13401.6 KKK16027.1 - 0.0087 16.3 0.0 0.08 13.2 0.0 2.6 1 1 0 1 1 1 1 AAA domain DUF4332 PF14229.6 KKK16027.1 - 0.099 12.9 0.1 0.3 11.4 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4332) Glyco_transf_90 PF05686.12 KKK16028.1 - 2.7e-13 49.6 0.2 6.2e-07 28.7 0.2 3.5 2 1 0 2 2 2 2 Glycosyl transferase family 90 Oxidored_FMN PF00724.20 KKK16043.1 - 2e-94 316.7 0.0 2.3e-94 316.5 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family PHA_synth_III_E PF09712.10 KKK16043.1 - 0.13 11.3 0.2 0.26 10.4 0.0 1.5 2 0 0 2 2 2 0 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) Pkinase PF00069.25 KKK16045.1 - 5.5e-54 183.3 5.5 4.5e-34 118.0 0.0 2.9 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 KKK16045.1 - 2.6e-36 125.3 0.0 4.9e-25 88.3 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 KKK16045.1 - 0.0052 15.6 4.4 0.11 11.2 0.0 2.3 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 KKK16045.1 - 0.01 15.2 1.1 0.02 14.3 0.0 1.9 2 0 0 2 2 2 0 Kinase-like APH PF01636.23 KKK16045.1 - 0.043 13.7 1.9 0.24 11.3 0.0 2.6 2 1 1 3 3 3 0 Phosphotransferase enzyme family DUF99 PF01949.16 KKK16045.1 - 0.17 11.3 1.0 0.32 10.4 1.0 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF99 DUF677 PF05055.12 KKK16045.1 - 0.18 10.6 8.5 0.28 10.0 8.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF677) DUF3896 PF13035.6 KKK16045.1 - 0.2 11.8 6.6 0.57 10.4 0.6 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3896) Colicin PF01024.19 KKK16045.1 - 0.45 10.4 1.7 0.79 9.6 1.7 1.3 1 0 0 1 1 1 0 Colicin pore forming domain ALMT PF11744.8 KKK16045.1 - 7.8 5.2 6.2 12 4.6 6.2 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter V_ATPase_I PF01496.19 KKK16045.1 - 8.6 4.1 6.1 12 3.6 6.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family BTB PF00651.31 KKK16046.1 - 3.1e-25 88.6 0.0 3.2e-14 53.1 0.1 2.6 2 0 0 2 2 2 2 BTB/POZ domain Wbp11 PF09429.10 KKK16047.1 - 4.8e-20 71.7 13.4 4.8e-20 71.7 13.4 2.6 3 1 0 3 3 3 1 WW domain binding protein 11 DUF3038 PF11237.8 KKK16047.1 - 0.0085 16.1 1.8 0.014 15.4 1.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3038) FUSC PF04632.12 KKK16047.1 - 1.3 7.5 2.3 2.4 6.6 2.3 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family Fungal_trans PF04082.18 KKK16048.1 - 5.7e-15 55.1 2.1 9e-15 54.4 2.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK16048.1 - 7.4e-09 35.6 10.8 1.5e-08 34.6 10.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Kelch_5 PF13854.6 KKK16049.1 - 1.8e-16 59.7 1.9 8.6e-15 54.3 1.0 3.5 3 0 0 3 3 3 1 Kelch motif Kelch_6 PF13964.6 KKK16049.1 - 3.5e-06 27.1 2.8 0.037 14.3 0.2 4.5 4 0 0 4 4 4 2 Kelch motif Kelch_1 PF01344.25 KKK16049.1 - 9.4e-06 25.1 0.1 0.015 14.9 0.1 3.5 3 0 0 3 3 3 2 Kelch motif Kelch_3 PF13415.6 KKK16049.1 - 4.3e-05 23.7 5.3 0.058 13.7 0.1 4.6 4 0 0 4 4 4 1 Galactose oxidase, central domain PTP_tm PF18861.1 KKK16049.1 - 0.01 15.8 0.0 0.02 14.9 0.0 1.5 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J Kelch_2 PF07646.15 KKK16049.1 - 0.017 15.1 0.5 13 6.0 0.1 4.5 4 0 0 4 4 4 0 Kelch motif MSP1a PF11670.8 KKK16049.1 - 0.15 11.3 1.1 0.25 10.6 1.1 1.2 1 0 0 1 1 1 0 Major surface protein 1a (MSP1a) DUF4381 PF14316.6 KKK16049.1 - 0.16 12.2 0.0 0.26 11.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Gram_pos_anchor PF00746.21 KKK16049.1 - 0.52 10.3 3.2 1.2 9.2 2.4 2.1 2 0 0 2 2 2 0 LPXTG cell wall anchor motif FAD_binding_3 PF01494.19 KKK16050.1 - 7.1e-16 58.4 0.4 7.1e-10 38.6 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KKK16050.1 - 4.6e-09 36.4 0.7 1.3e-08 34.9 0.7 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KKK16050.1 - 2e-06 27.3 0.1 3.6e-06 26.4 0.1 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KKK16050.1 - 9e-06 25.3 0.0 1.4e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.24 KKK16050.1 - 1.9e-05 24.4 5.7 2.7e-05 23.9 4.7 1.7 1 1 1 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KKK16050.1 - 5.4e-05 22.5 0.0 7.6e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.24 KKK16050.1 - 0.00057 19.3 0.3 0.0011 18.4 0.1 1.5 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 KKK16050.1 - 0.0013 19.2 1.0 0.0039 17.7 1.0 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KKK16050.1 - 0.0043 16.2 0.8 0.0069 15.5 0.8 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Lycopene_cycl PF05834.12 KKK16050.1 - 0.005 15.9 0.0 0.0069 15.5 0.0 1.1 1 0 0 1 1 1 1 Lycopene cyclase protein Rossmann-like PF10727.9 KKK16050.1 - 0.0063 16.4 0.5 0.012 15.5 0.5 1.5 1 0 0 1 1 1 1 Rossmann-like domain Pyr_redox_3 PF13738.6 KKK16050.1 - 0.015 14.6 0.9 0.077 12.2 1.1 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KKK16050.1 - 0.022 13.5 1.2 0.034 12.8 1.2 1.3 1 0 0 1 1 1 0 HI0933-like protein Trp_halogenase PF04820.14 KKK16050.1 - 0.039 12.8 1.0 0.3 9.9 0.8 2.0 2 0 0 2 2 2 0 Tryptophan halogenase AlaDh_PNT_C PF01262.21 KKK16050.1 - 0.041 13.2 0.3 0.074 12.3 0.3 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain MCRA PF06100.11 KKK16050.1 - 0.042 12.7 0.2 0.072 11.9 0.2 1.3 1 0 0 1 1 1 0 MCRA family ApbA PF02558.16 KKK16050.1 - 4.2 7.0 5.0 0.87 9.2 1.2 1.8 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA BRO1 PF03097.18 KKK16052.1 - 1.2e-08 34.2 0.0 2e-08 33.5 0.1 1.4 2 0 0 2 2 2 1 BRO1-like domain Glt_symporter PF03616.14 KKK16052.1 - 2.7 6.6 5.0 12 4.4 3.2 2.0 2 0 0 2 2 2 0 Sodium/glutamate symporter NDUFB10 PF10249.9 KKK16053.1 - 0.0093 16.5 0.0 0.01 16.3 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit 10 TAFII55_N PF04658.13 KKK16054.1 - 5.3e-52 175.8 0.0 1.6e-51 174.2 0.0 1.8 2 0 0 2 2 2 1 TAFII55 protein conserved region YqjK PF13997.6 KKK16054.1 - 0.31 11.3 1.8 0.77 10.0 1.8 1.6 1 0 0 1 1 1 0 YqjK-like protein MnmE_helical PF12631.7 KKK16054.1 - 1.2 9.2 5.0 0.29 11.3 0.2 2.2 1 1 1 2 2 2 0 MnmE helical domain CAF1A PF12253.8 KKK16054.1 - 5.6 7.2 14.7 4.5 7.5 7.0 2.7 2 0 0 2 2 2 0 Chromatin assembly factor 1 subunit A Bromo_TP PF07524.13 KKK16055.1 - 2.9e-09 36.8 0.0 5.4e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated TFIID-31kDa PF02291.15 KKK16055.1 - 0.0097 16.0 0.0 0.015 15.3 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit ECH_1 PF00378.20 KKK16056.1 - 9.5e-23 80.8 0.0 1.1e-22 80.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KKK16056.1 - 0.0007 19.2 0.0 0.00074 19.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Glyco_transf_34 PF05637.12 KKK16058.1 - 2.6e-30 105.9 0.0 3.1e-30 105.7 0.0 1.1 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family GPP34 PF05719.11 KKK16086.1 - 8e-43 146.8 0.1 1e-42 146.5 0.1 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) TRAPPC9-Trs120 PF08626.11 KKK16086.1 - 0.13 9.6 0.0 0.16 9.3 0.0 1.0 1 0 0 1 1 1 0 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit CBS PF00571.28 KKK16087.1 - 7.3e-21 74.4 7.0 2.8e-06 27.7 0.0 5.3 5 0 0 5 5 5 5 CBS domain DUF2183 PF09949.9 KKK16089.1 - 5e-33 113.4 0.2 1.1e-32 112.3 0.2 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) LNS2 PF08235.13 KKK16089.1 - 0.00028 20.4 0.0 0.00042 19.9 0.0 1.2 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) RTA1 PF04479.13 KKK16093.1 - 2e-48 164.8 3.9 2e-48 164.8 3.9 2.0 1 1 1 2 2 2 2 RTA1 like protein DUF4239 PF14023.6 KKK16093.1 - 0.078 12.7 1.4 0.15 11.7 1.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) NUDE_C PF04880.13 KKK16094.1 - 2.3 8.7 5.9 2.5 8.5 5.9 1.2 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region FHA PF00498.26 KKK16095.1 - 5.8e-17 61.8 0.0 1.2e-16 60.7 0.0 1.6 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KKK16095.1 - 0.00022 21.5 0.0 0.00058 20.1 0.0 1.7 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain CENP-Q PF13094.6 KKK16095.1 - 0.0088 16.3 8.9 0.0088 16.3 8.9 3.4 2 1 1 3 3 3 1 CENP-Q, a CENPA-CAD centromere complex subunit YhfZ_C PF14503.6 KKK16095.1 - 0.031 13.8 0.0 0.057 12.9 0.0 1.3 1 0 0 1 1 1 0 YhfZ C-terminal domain Cbl_N PF02262.16 KKK16095.1 - 0.048 13.7 3.3 0.99 9.4 0.5 2.4 2 0 0 2 2 2 0 CBL proto-oncogene N-terminal domain 1 ATPase_2 PF01637.18 KKK16095.1 - 0.11 12.4 0.1 2 8.2 0.9 2.0 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea Cep57_MT_bd PF06657.13 KKK16095.1 - 0.84 10.1 11.8 0.41 11.1 7.0 2.7 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 DUF2203 PF09969.9 KKK16095.1 - 6.9 7.4 13.3 4.5 8.0 0.1 3.4 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2203) Romo1 PF10247.9 KKK16096.1 - 4.9e-28 97.3 15.7 6.6e-28 96.9 15.7 1.2 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 Tim17 PF02466.19 KKK16096.1 - 0.0017 18.7 2.5 0.0023 18.3 2.5 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family AFP PF02420.15 KKK16096.1 - 0.19 12.2 2.0 0.45 11.0 2.0 1.7 1 0 0 1 1 1 0 Insect antifreeze protein repeat Rpp20 PF12328.8 KKK16097.1 - 8.6e-53 178.0 3.2 1.2e-52 177.5 3.2 1.2 1 0 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.21 KKK16097.1 - 6.9e-19 67.4 0.4 1.2e-18 66.7 0.4 1.4 1 0 0 1 1 1 1 Alba DUF5567 PF17722.1 KKK16097.1 - 0.0019 18.1 0.6 0.0025 17.7 0.6 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5567) LRR_8 PF13855.6 KKK16098.1 - 8.6e-11 41.4 5.3 2.8e-08 33.4 2.8 2.5 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 KKK16098.1 - 1.4e-06 28.5 9.2 0.00066 20.0 0.1 3.3 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KKK16098.1 - 0.36 11.6 8.4 4.8 8.1 0.0 4.7 5 0 0 5 5 5 0 Leucine Rich Repeat DUF3292 PF11696.8 KKK16098.1 - 0.38 9.1 1.3 0.55 8.5 1.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) APH PF01636.23 KKK16099.1 - 7.5e-20 71.9 0.0 9.9e-20 71.5 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KKK16099.1 - 0.0011 18.6 0.0 0.0019 17.8 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 KKK16099.1 - 0.052 13.1 0.0 0.65 9.6 0.0 2.1 2 0 0 2 2 2 0 RIO1 family Fic PF02661.18 KKK16100.1 - 1e-10 42.4 0.3 2.1e-10 41.4 0.3 1.5 1 1 0 1 1 1 1 Fic/DOC family Transketolase_N PF00456.21 KKK16101.1 - 6.9e-156 518.3 0.1 9.3e-156 517.9 0.1 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 KKK16101.1 - 2.9e-44 150.9 0.0 4.9e-44 150.1 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain DXP_synthase_N PF13292.6 KKK16101.1 - 0.00019 20.8 0.0 0.0006 19.1 0.0 1.7 1 1 1 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.20 KKK16101.1 - 0.00037 19.6 0.1 0.00084 18.4 0.1 1.5 1 0 0 1 1 1 1 Dehydrogenase E1 component Transketolase_C PF02780.20 KKK16101.1 - 0.018 15.0 0.0 0.047 13.6 0.0 1.7 1 0 0 1 1 1 0 Transketolase, C-terminal domain GtrA PF04138.14 KKK16101.1 - 0.093 13.0 0.0 0.21 11.8 0.0 1.6 1 0 0 1 1 1 0 GtrA-like protein SET PF00856.28 KKK16102.1 - 0.012 16.0 0.0 0.023 15.1 0.0 1.5 1 0 0 1 1 1 0 SET domain Fungal_trans PF04082.18 KKK16103.1 - 1e-39 136.2 0.0 2e-39 135.2 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK16103.1 - 2e-08 34.2 14.9 3.4e-08 33.5 14.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Trimer_CC PF08954.11 KKK16103.1 - 0.13 11.9 0.6 0.37 10.4 0.6 1.8 1 0 0 1 1 1 0 Trimerisation motif DUF4635 PF15466.6 KKK16103.1 - 0.16 11.5 2.2 0.25 10.9 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4635) Cep57_MT_bd PF06657.13 KKK16103.1 - 0.18 12.3 2.5 13 6.3 0.2 2.6 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 MMR_HSR1_C PF08438.10 KKK16104.1 - 1.3e-36 125.6 0.0 2.6e-36 124.6 0.0 1.5 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.23 KKK16104.1 - 9.2e-15 54.7 0.0 2.6e-14 53.3 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KKK16104.1 - 0.00038 20.0 0.1 0.0055 16.2 0.1 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 KKK16104.1 - 0.0029 17.2 0.1 0.46 10.0 0.0 2.7 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 KKK16104.1 - 0.0088 16.1 1.4 0.3 11.1 0.5 2.6 3 0 0 3 3 3 1 Dynamin family ABC_tran PF00005.27 KKK16104.1 - 0.051 14.1 0.0 0.35 11.4 0.0 2.1 2 0 0 2 2 2 0 ABC transporter AAA_33 PF13671.6 KKK16104.1 - 0.08 13.1 0.1 9 6.5 0.1 2.3 2 0 0 2 2 2 0 AAA domain Ploopntkinase3 PF18751.1 KKK16104.1 - 0.11 12.4 0.0 0.29 11.0 0.0 1.6 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 AAA_16 PF13191.6 KKK16104.1 - 0.12 12.7 0.1 0.51 10.7 0.0 2.0 1 1 0 2 2 2 0 AAA ATPase domain RHD3 PF05879.12 KKK16104.1 - 0.13 10.4 0.8 1 7.4 0.0 2.0 2 0 0 2 2 2 0 Root hair defective 3 GTP-binding protein (RHD3) MMR_HSR1_Xtn PF16897.5 KKK16104.1 - 0.15 12.0 0.1 0.36 10.9 0.1 1.6 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain KTI12 PF08433.10 KKK16104.1 - 0.18 11.3 0.1 0.38 10.2 0.1 1.5 1 0 0 1 1 1 0 Chromatin associated protein KTI12 ATP_bind_1 PF03029.17 KKK16104.1 - 0.26 11.0 0.3 22 4.7 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Ribosomal_L7Ae PF01248.26 KKK16108.1 - 2e-19 69.1 1.1 1.7e-18 66.1 1.1 2.3 1 1 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family MAD PF05557.13 KKK16109.1 - 1.8e-56 191.9 82.6 4.7e-48 164.0 83.7 2.0 2 0 0 2 2 2 2 Mitotic checkpoint protein Aldo_ket_red PF00248.21 KKK16111.1 - 2.3e-38 132.0 0.0 3.8e-36 124.8 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Kdo PF06293.14 KKK16112.1 - 4.4e-10 39.2 0.0 2.5e-09 36.8 0.0 2.1 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 KKK16112.1 - 2.2e-07 30.5 0.0 2.4e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KKK16112.1 - 2.4e-07 30.9 0.1 0.0046 16.9 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 KKK16112.1 - 0.00017 21.0 0.0 0.00024 20.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 KKK16112.1 - 0.0054 16.3 0.0 0.1 12.2 0.0 2.5 2 1 0 2 2 2 1 RIO1 family Pkinase_fungal PF17667.1 KKK16112.1 - 0.0056 15.5 0.0 0.0072 15.2 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Chitin_synth_1 PF01644.17 KKK16113.1 - 5.1e-70 234.7 0.0 1.7e-69 232.9 0.0 1.8 2 0 0 2 2 2 1 Chitin synthase UQ_con PF00179.26 KKK16113.1 - 3.8e-37 127.1 0.0 6.3e-37 126.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Chitin_synth_1N PF08407.11 KKK16113.1 - 4.9e-28 96.9 0.0 9.5e-28 96.0 0.0 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 KKK16113.1 - 1.7e-23 83.1 0.0 1.8e-20 73.1 0.0 2.1 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 KKK16113.1 - 4.6e-10 39.8 2.5 4.9e-10 39.6 0.1 2.4 3 1 0 3 3 3 1 Glycosyl transferase family group 2 PsbX PF06596.11 KKK16113.1 - 1.9 8.6 4.3 6.5 6.9 4.3 1.9 1 0 0 1 1 1 0 Photosystem II reaction centre X protein (PsbX) RNA_pol_Rpb1_1 PF04997.12 KKK16114.1 - 3e-85 286.3 0.0 5.3e-85 285.5 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 KKK16114.1 - 1.2e-81 274.1 1.0 1.8e-81 273.5 1.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 KKK16114.1 - 2.1e-71 239.5 0.1 6.1e-71 238.0 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 KKK16114.1 - 2.8e-33 115.1 0.0 1.2e-32 113.0 0.0 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 KKK16114.1 - 2.8e-27 94.8 0.1 7.6e-27 93.4 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 GTP_EFTU PF00009.27 KKK16115.1 - 1.5e-50 171.5 0.0 2.6e-50 170.7 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.12 KKK16115.1 - 8.2e-43 144.9 3.3 1.3e-42 144.3 3.3 1.3 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.24 KKK16115.1 - 4.4e-20 71.5 0.0 9.1e-20 70.5 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KKK16115.1 - 1.4e-05 25.3 0.3 3.3e-05 24.2 0.0 1.8 2 0 0 2 2 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KKK16115.1 - 1.7e-05 24.8 0.0 4.4e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.22 KKK16115.1 - 3.7e-05 23.4 0.0 0.00013 21.6 0.0 1.9 2 0 0 2 2 2 1 Ras family EFG_II PF14492.6 KKK16115.1 - 0.0043 17.1 0.0 0.012 15.7 0.0 1.8 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1_Xtn PF16897.5 KKK16115.1 - 0.0053 16.8 0.0 0.012 15.7 0.0 1.5 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain RF3_C PF16658.5 KKK16115.1 - 0.0067 16.3 0.0 0.015 15.1 0.0 1.6 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain RsgA_GTPase PF03193.16 KKK16115.1 - 0.022 14.7 0.0 0.1 12.5 0.0 2.1 1 1 1 2 2 2 0 RsgA GTPase SRPRB PF09439.10 KKK16115.1 - 0.049 13.1 0.0 0.1 12.0 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Snurportin1 PF11538.8 KKK16115.1 - 0.21 11.8 2.3 0.58 10.4 2.3 1.7 1 0 0 1 1 1 0 Snurportin1 HORMA PF02301.18 KKK16116.1 - 2.2e-33 115.7 0.1 2.6e-33 115.4 0.1 1.0 1 0 0 1 1 1 1 HORMA domain Arcadin_1 PF18653.1 KKK16116.1 - 0.014 15.4 0.1 3.9 7.6 0.0 2.2 2 0 0 2 2 2 0 Arcadin 1 DUF2660 PF10859.8 KKK16116.1 - 0.027 14.9 0.0 0.084 13.3 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2660) DUF4760 PF15956.5 KKK16116.1 - 0.037 14.1 0.5 0.11 12.6 0.1 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4760) FlaG PF03646.15 KKK16116.1 - 7.2 6.8 10.9 23 5.2 3.3 2.8 2 1 0 2 2 2 0 FlaG protein zf_CCCH_4 PF18345.1 KKK16117.1 - 6.1e-06 26.1 3.8 1.1e-05 25.3 3.8 1.4 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_4 PF18044.1 KKK16117.1 - 0.00072 19.3 2.3 0.0012 18.6 2.3 1.4 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH PF00642.24 KKK16117.1 - 0.012 15.5 0.7 0.02 14.8 0.7 1.3 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 KKK16117.1 - 0.029 14.8 1.3 0.054 14.0 1.3 1.5 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 KKK16117.1 - 0.047 13.9 0.1 0.17 12.1 0.1 2.0 1 0 0 1 1 1 0 Zinc-finger containing family Sec1 PF00995.23 KKK16118.1 - 9.6e-129 431.2 0.0 1.1e-128 431.0 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Pkinase_C PF00433.24 KKK16118.1 - 0.04 14.6 0.0 0.18 12.5 0.0 2.2 1 0 0 1 1 1 0 Protein kinase C terminal domain STE2 PF02116.15 KKK16119.1 - 9.8e-103 343.3 16.8 1.2e-102 343.1 16.8 1.0 1 0 0 1 1 1 1 Fungal pheromone mating factor STE2 GPCR DUF3754 PF12576.8 KKK16119.1 - 0.12 12.4 1.5 0.15 12.0 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3754) PufQ PF05398.11 KKK16119.1 - 0.37 11.0 2.8 11 6.2 0.1 2.4 1 1 1 2 2 2 0 PufQ cytochrome subunit UEV PF05743.13 KKK16120.1 - 5.7e-39 132.7 0.1 9e-39 132.1 0.1 1.3 1 0 0 1 1 1 1 UEV domain UQ_con PF00179.26 KKK16120.1 - 0.0044 16.7 0.1 0.0095 15.6 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme KASH_CCD PF14662.6 KKK16120.1 - 0.0093 15.8 0.9 0.014 15.2 0.9 1.2 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH KLRAQ PF10205.9 KKK16120.1 - 0.016 15.4 0.3 0.03 14.6 0.3 1.3 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein Striatin PF08232.12 KKK16120.1 - 0.036 14.6 1.5 0.038 14.6 0.2 1.7 2 0 0 2 2 2 0 Striatin family Spectrin PF00435.21 KKK16120.1 - 0.2 12.1 0.9 0.41 11.2 0.9 1.4 1 0 0 1 1 1 0 Spectrin repeat TMF_TATA_bd PF12325.8 KKK16120.1 - 0.31 11.3 2.0 0.5 10.6 2.0 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding BAR PF03114.18 KKK16121.1 - 1.9e-69 233.9 6.2 2.4e-69 233.6 6.2 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.28 KKK16121.1 - 5.6e-15 54.7 0.0 9.7e-15 53.9 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KKK16121.1 - 2.9e-09 36.7 0.0 4.9e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KKK16121.1 - 2.3e-07 30.4 0.0 6.1e-07 29.0 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain CT_C_D PF02682.16 KKK16121.1 - 0.21 11.3 1.0 0.35 10.6 0.4 1.6 2 0 0 2 2 2 0 Carboxyltransferase domain, subdomain C and D BRE1 PF08647.11 KKK16121.1 - 0.29 11.2 9.3 1.6 8.8 0.8 2.8 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase TMPIT PF07851.13 KKK16121.1 - 5.2 6.2 7.6 2.8 7.1 0.2 2.1 1 1 1 2 2 2 0 TMPIT-like protein Aminotran_5 PF00266.19 KKK16122.1 - 4.4e-41 141.1 0.0 5.5e-41 140.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V DUF3942 PF13078.6 KKK16122.1 - 0.044 14.1 0.2 0.15 12.3 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3942) AlaDh_PNT_C PF01262.21 KKK16122.1 - 0.073 12.4 0.2 0.14 11.4 0.2 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Beta_elim_lyase PF01212.21 KKK16122.1 - 0.096 12.0 0.1 0.16 11.3 0.1 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase Opy2 PF09463.10 KKK16123.1 - 3.1e-10 40.2 23.0 4.9e-10 39.5 23.0 1.3 1 0 0 1 1 1 1 Opy2 protein Phage_holin_2_1 PF04971.12 KKK16123.1 - 0.046 13.7 0.0 0.093 12.7 0.0 1.5 1 0 0 1 1 1 0 Bacteriophage P21 holin S Phage_holin_2_4 PF16082.5 KKK16123.1 - 0.053 13.2 0.1 0.1 12.3 0.1 1.4 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like SKG6 PF08693.10 KKK16123.1 - 0.063 12.7 1.4 0.16 11.4 1.4 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Syndecan PF01034.20 KKK16123.1 - 0.13 12.2 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 Syndecan domain DUF2981 PF11200.8 KKK16123.1 - 3.8 7.1 6.6 6.5 6.4 6.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) Beta-APP PF03494.13 KKK16123.1 - 5.5 6.9 7.4 9.2 6.2 7.4 1.3 1 0 0 1 1 1 0 Beta-amyloid peptide (beta-APP) Aldo_ket_red PF00248.21 KKK16124.1 - 1.4e-13 50.7 0.0 2.1e-13 50.1 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family DUF1120 PF06551.12 KKK16124.1 - 0.071 13.3 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1120) RRM_1 PF00076.22 KKK16130.1 - 1.1e-05 25.1 0.0 1.9e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Methyltransf_28 PF02636.17 KKK16131.1 - 4e-84 282.3 0.0 5.6e-84 281.8 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase BUD22 PF09073.10 KKK16132.1 - 0.39 10.0 19.8 0.4 10.0 19.8 1.0 1 0 0 1 1 1 0 BUD22 Zip PF02535.22 KKK16132.1 - 0.41 9.8 8.2 0.44 9.7 8.2 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter RR_TM4-6 PF06459.12 KKK16132.1 - 0.42 10.4 18.3 0.44 10.3 18.3 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CobT PF06213.12 KKK16132.1 - 0.5 9.7 23.6 0.6 9.5 23.6 1.0 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Myc_N PF01056.18 KKK16132.1 - 0.77 9.6 19.2 0.87 9.4 19.2 1.0 1 0 0 1 1 1 0 Myc amino-terminal region PAF PF15715.5 KKK16132.1 - 0.88 10.2 13.3 1.1 9.8 13.3 1.1 1 0 0 1 1 1 0 PCNA-associated factor histone like domain Pox_Ag35 PF03286.14 KKK16132.1 - 1.1 9.0 16.6 1.3 8.8 16.6 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein MDM31_MDM32 PF08118.11 KKK16132.1 - 1.6 7.3 5.7 1.8 7.1 5.7 1.0 1 0 0 1 1 1 0 Yeast mitochondrial distribution and morphology (MDM) proteins NOA36 PF06524.12 KKK16132.1 - 1.9 7.7 15.1 2.2 7.5 15.1 1.1 1 0 0 1 1 1 0 NOA36 protein DDHD PF02862.17 KKK16132.1 - 2.6 8.1 7.0 2.8 8.0 7.0 1.1 1 0 0 1 1 1 0 DDHD domain DUF5427 PF10310.9 KKK16132.1 - 3.4 6.5 18.8 3.9 6.3 18.8 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5427) VIR_N PF15912.5 KKK16132.1 - 4.2 6.9 16.1 4.6 6.8 16.1 1.0 1 0 0 1 1 1 0 Virilizer, N-terminal Raftlin PF15250.6 KKK16132.1 - 4.4 6.0 10.0 4.5 5.9 10.0 1.0 1 0 0 1 1 1 0 Raftlin Neur_chan_memb PF02932.16 KKK16132.1 - 4.8 7.2 5.3 5.1 7.1 5.3 1.0 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region RNA_pol_3_Rpc31 PF11705.8 KKK16132.1 - 5.8 7.1 22.2 7.2 6.8 22.2 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 DUF4820 PF16091.5 KKK16132.1 - 6 6.2 11.6 7.8 5.8 11.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) MID_MedPIWI PF18296.1 KKK16132.1 - 6.1 6.5 7.4 6.7 6.4 7.4 1.1 1 0 0 1 1 1 0 MID domain of medPIWI RPN2_C PF18004.1 KKK16132.1 - 6.5 6.7 17.7 9.6 6.1 17.7 1.3 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain DUF1770 PF08589.10 KKK16132.1 - 6.7 7.7 11.8 7.9 7.5 11.8 1.1 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF1770) Nop14 PF04147.12 KKK16132.1 - 6.8 4.8 23.3 7 4.7 23.3 1.0 1 0 0 1 1 1 0 Nop14-like family PPP4R2 PF09184.11 KKK16132.1 - 7.2 6.1 24.5 8.1 5.9 24.5 1.0 1 0 0 1 1 1 0 PPP4R2 NPR3 PF03666.13 KKK16132.1 - 7.7 5.2 12.6 8.1 5.1 12.6 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Presenilin PF01080.17 KKK16132.1 - 9.7 4.8 16.3 10 4.7 16.3 1.0 1 0 0 1 1 1 0 Presenilin XRN_M PF17846.1 KKK16132.1 - 9.7 5.0 10.1 11 4.8 10.1 1.0 1 0 0 1 1 1 0 Xrn1 helical domain SpoIIP PF07454.11 KKK16132.1 - 9.8 5.5 14.4 12 5.2 14.4 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Acyltransferase PF01553.21 KKK16133.1 - 8.9e-10 38.3 0.0 0.00047 19.8 0.0 2.2 2 0 0 2 2 2 2 Acyltransferase Lipase_GDSL PF00657.22 KKK16134.1 - 1.4e-08 35.0 0.1 1.7e-08 34.7 0.1 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase PhrC_PhrF PF11131.8 KKK16134.1 - 0.034 13.7 1.3 0.071 12.7 1.3 1.5 1 0 0 1 1 1 0 Rap-phr extracellular signalling Cellulase PF00150.18 KKK16135.1 - 3.4e-55 187.5 0.6 4.4e-55 187.1 0.6 1.0 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) XPG_N PF00752.17 KKK16136.1 - 2.2e-36 124.4 0.1 6.8e-36 122.8 0.0 1.9 2 0 0 2 2 2 1 XPG N-terminal domain XPG_I PF00867.18 KKK16136.1 - 1.9e-25 89.0 0.0 6.2e-25 87.4 0.0 2.0 1 0 0 1 1 1 1 XPG I-region UIM PF02809.20 KKK16136.1 - 2e-05 24.2 2.3 2e-05 24.2 2.3 3.9 3 0 0 3 3 3 2 Ubiquitin interaction motif 5_3_exonuc PF01367.20 KKK16136.1 - 0.00073 20.1 0.0 0.0027 18.3 0.0 2.0 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold Transposase_20 PF02371.16 KKK16136.1 - 0.063 13.6 0.0 0.15 12.4 0.0 1.6 1 0 0 1 1 1 0 Transposase IS116/IS110/IS902 family WD40 PF00400.32 KKK16137.1 - 7.1e-17 61.5 21.5 2.8e-05 24.8 0.9 10.8 10 0 0 10 10 10 6 WD domain, G-beta repeat Nucleoporin_N PF08801.11 KKK16137.1 - 0.2 10.4 2.2 1.3 7.7 0.0 3.2 4 2 0 4 4 4 0 Nup133 N terminal like Pil1 PF13805.6 KKK16138.1 - 5.4e-123 409.7 0.1 7e-123 409.3 0.1 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 FAM92 PF06730.11 KKK16138.1 - 0.39 10.1 3.8 0.22 10.9 1.8 1.6 2 0 0 2 2 2 0 FAM92 protein Dioxygenase_C PF00775.21 KKK16139.1 - 0.17 11.3 0.0 0.21 11.0 0.0 1.1 1 0 0 1 1 1 0 Dioxygenase CASP_C PF08172.12 KKK16140.1 - 1.5e-90 303.0 2.0 1.5e-90 303.0 2.0 4.2 2 1 0 3 3 3 1 CASP C terminal MotB_plug PF13677.6 KKK16140.1 - 0.034 13.7 0.6 0.095 12.3 0.6 1.8 1 0 0 1 1 1 0 Membrane MotB of proton-channel complex MotA/MotB UPF0184 PF03670.13 KKK16140.1 - 0.41 11.1 11.9 1.2 9.6 0.5 4.2 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0184) SlyX PF04102.12 KKK16140.1 - 0.67 10.6 0.0 0.67 10.6 0.0 6.6 6 1 1 7 7 7 0 SlyX Rootletin PF15035.6 KKK16140.1 - 1.7 8.6 49.6 0.099 12.7 7.6 4.6 4 1 1 5 5 5 0 Ciliary rootlet component, centrosome cohesion GIT_CC PF16559.5 KKK16140.1 - 3.4 7.6 16.7 0.54 10.2 1.0 4.4 4 1 0 4 4 4 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF3584 PF12128.8 KKK16140.1 - 8.9 3.7 46.8 0.042 11.4 24.9 3.8 3 1 1 4 4 4 0 Protein of unknown function (DUF3584) Vps39_2 PF10367.9 KKK16141.1 - 6.9e-05 23.3 0.0 0.00036 21.0 0.0 2.1 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.9 KKK16141.1 - 0.0058 16.9 0.2 0.075 13.3 0.1 2.6 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 Fibrillarin PF01269.17 KKK16142.1 - 5.8e-104 346.1 0.0 7e-104 345.9 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.10 KKK16142.1 - 3.1e-06 27.0 0.1 5.4e-06 26.3 0.1 1.3 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.19 KKK16142.1 - 0.055 13.2 0.1 0.072 12.8 0.1 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF3455 PF11937.8 KKK16143.1 - 2.4e-50 171.0 0.1 3.5e-50 170.5 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) DUF2990 PF11693.8 KKK16143.1 - 1.8e-22 79.3 1.2 4.2e-22 78.1 1.2 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2990) Peptidase_M16 PF00675.20 KKK16144.1 - 1.7e-56 190.3 0.2 9.8e-56 187.9 0.3 2.2 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 KKK16144.1 - 1.8e-39 135.6 0.0 1.2e-37 129.7 0.0 2.3 2 0 0 2 2 2 1 Peptidase M16 inactive domain Epimerase PF01370.21 KKK16144.1 - 4e-19 69.0 0.0 7.4e-19 68.2 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KKK16144.1 - 3.9e-11 42.5 0.0 6e-11 41.9 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KKK16144.1 - 1.1e-10 41.5 0.0 1.9e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 KKK16144.1 - 1.5e-05 24.2 0.0 3.1e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.25 KKK16144.1 - 0.00047 19.7 0.0 0.0034 16.9 0.0 2.3 2 0 0 2 2 2 1 short chain dehydrogenase NAD_binding_10 PF13460.6 KKK16144.1 - 0.0064 16.4 0.0 0.017 15.0 0.0 1.7 1 0 0 1 1 1 1 NAD(P)H-binding Ldh_1_N PF00056.23 KKK16144.1 - 0.036 14.2 0.0 0.16 12.1 0.0 2.1 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain NAD_binding_4 PF07993.12 KKK16144.1 - 0.045 12.9 0.0 1.7 7.8 0.0 2.5 1 1 0 1 1 1 0 Male sterility protein Semialdhyde_dh PF01118.24 KKK16144.1 - 0.063 13.7 0.0 0.42 11.0 0.0 2.5 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain KR PF08659.10 KKK16144.1 - 0.088 12.7 0.0 0.34 10.8 0.0 1.9 2 0 0 2 2 2 0 KR domain INO80_Ies4 PF08193.11 KKK16150.1 - 7.1e-70 235.7 25.7 2.2e-67 227.6 25.7 2.0 1 1 0 1 1 1 1 INO80 complex subunit Ies4 Pol_alpha_B_N PF08418.10 KKK16150.1 - 9.1 6.2 9.5 2 8.3 5.4 1.8 2 0 0 2 2 2 0 DNA polymerase alpha subunit B N-terminal Arginase PF00491.21 KKK16153.1 - 4.3e-76 256.1 0.2 4.9e-76 255.9 0.2 1.0 1 0 0 1 1 1 1 Arginase family Glyco_hydro_47 PF01532.20 KKK16160.1 - 4e-142 474.3 0.0 5.4e-142 473.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Ank_2 PF12796.7 KKK16161.1 - 7e-40 135.5 3.0 1.6e-12 47.8 0.3 4.8 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KKK16161.1 - 3.9e-38 129.3 6.7 3.1e-12 46.8 0.3 7.0 5 2 2 7 7 7 5 Ankyrin repeats (many copies) Ank PF00023.30 KKK16161.1 - 1e-36 123.7 8.1 1.1e-06 28.9 0.2 9.0 8 0 0 8 8 8 7 Ankyrin repeat Ank_3 PF13606.6 KKK16161.1 - 3.4e-29 97.6 5.8 0.00012 22.2 0.1 9.1 9 0 0 9 9 9 6 Ankyrin repeat Ank_5 PF13857.6 KKK16161.1 - 2.2e-27 94.7 9.7 4.9e-07 29.9 0.6 6.7 4 3 2 6 6 6 5 Ankyrin repeats (many copies) CorA PF01544.18 KKK16161.1 - 4.3e-12 45.9 0.5 1.2e-11 44.5 0.4 1.8 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein PRP1_N PF06424.12 KKK16161.1 - 0.083 13.3 0.4 0.21 12.0 0.4 1.6 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal Utp11 PF03998.13 KKK16162.1 - 6.8e-22 78.6 15.6 9.4e-22 78.1 15.6 1.2 1 0 0 1 1 1 1 Utp11 protein BUD22 PF09073.10 KKK16162.1 - 0.02 14.3 18.7 0.023 14.1 18.7 1.1 1 0 0 1 1 1 0 BUD22 SET PF00856.28 KKK16162.1 - 3.2 8.1 5.8 4.8 7.5 5.8 1.5 1 1 0 1 1 1 0 SET domain rRNA_processing PF08524.11 KKK16162.1 - 3.5 7.6 21.3 1.2 9.2 17.9 1.9 1 1 1 2 2 2 0 rRNA processing Presenilin PF01080.17 KKK16162.1 - 7.9 5.1 6.1 10 4.7 6.1 1.2 1 0 0 1 1 1 0 Presenilin Histidinol_dh PF00815.20 KKK16163.1 - 1.3e-159 531.6 4.7 1.8e-159 531.2 4.7 1.2 1 0 0 1 1 1 1 Histidinol dehydrogenase PRA-CH PF01502.18 KKK16163.1 - 4.5e-23 80.9 0.1 1.2e-22 79.5 0.1 1.7 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.17 KKK16163.1 - 1.7e-15 57.2 0.3 5.8e-15 55.5 0.3 2.0 1 0 0 1 1 1 1 Phosphoribosyl-ATP pyrophosphohydrolase MazG PF03819.17 KKK16163.1 - 0.0095 16.1 0.2 0.023 14.9 0.2 1.6 1 0 0 1 1 1 1 MazG nucleotide pyrophosphohydrolase domain Phage_TTP_13 PF16463.5 KKK16163.1 - 0.11 12.0 0.0 2.3 7.8 0.0 2.3 2 0 0 2 2 2 0 Phage tail tube protein family Ribosomal_60s PF00428.19 KKK16163.1 - 3.9 8.1 6.3 0.5 11.0 0.8 2.5 2 0 0 2 2 2 0 60s Acidic ribosomal protein Thiamine_BP PF01910.17 KKK16164.1 - 3.5e-27 94.2 0.1 4e-27 94.0 0.1 1.0 1 0 0 1 1 1 1 Thiamine-binding protein Golgin_A5 PF09787.9 KKK16165.1 - 0.0018 17.8 2.3 0.0038 16.8 2.3 1.4 1 0 0 1 1 1 1 Golgin subfamily A member 5 NUP214 PF16755.5 KKK16165.1 - 0.0038 16.5 0.1 0.011 15.1 0.1 1.6 1 1 0 1 1 1 1 Nucleoporin or Nuclear pore complex subunit NUP214=Nup159 ANAPC4_WD40 PF12894.7 KKK16165.1 - 0.0046 17.2 0.1 0.022 15.0 0.0 2.2 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Syntaxin-6_N PF09177.11 KKK16165.1 - 0.015 15.8 0.7 0.036 14.6 0.7 1.6 1 0 0 1 1 1 0 Syntaxin 6, N-terminal DUF1658 PF07871.11 KKK16165.1 - 0.2 11.6 2.4 4.3 7.5 0.1 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1658) Spc7 PF08317.11 KKK16165.1 - 0.28 10.0 1.2 0.47 9.3 1.2 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Cut12 PF11500.8 KKK16165.1 - 0.37 10.7 3.9 0.93 9.4 3.9 1.6 1 0 0 1 1 1 0 Spindle pole body formation-associated protein Baculo_PEP_C PF04513.12 KKK16165.1 - 0.5 10.4 1.8 1.3 9.1 1.5 1.7 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4110 PF13422.6 KKK16166.1 - 6.4e-33 112.7 2.5 6.4e-33 112.7 2.5 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF4110) Kelch_3 PF13415.6 KKK16166.1 - 1.5e-28 98.5 12.1 2.2e-08 34.2 0.1 6.9 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_4 PF13418.6 KKK16166.1 - 9.1e-27 92.8 14.0 1.7e-07 31.1 0.0 6.3 6 1 0 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.6 KKK16166.1 - 7.8e-16 57.7 3.8 8.1e-05 22.5 0.0 6.3 6 0 0 6 6 6 4 Kelch motif Kelch_6 PF13964.6 KKK16166.1 - 4.9e-14 52.0 6.2 0.003 17.8 0.2 5.4 6 0 0 6 6 6 3 Kelch motif Kelch_2 PF07646.15 KKK16166.1 - 1.2e-11 44.0 10.4 0.0061 16.5 0.0 5.9 6 1 0 6 6 6 3 Kelch motif Kelch_1 PF01344.25 KKK16166.1 - 2.5e-09 36.6 4.3 0.14 11.8 0.1 5.2 5 1 0 5 5 5 3 Kelch motif S-antigen PF05756.11 KKK16166.1 - 0.56 10.6 3.8 2.9 8.3 3.8 2.2 1 0 0 1 1 1 0 S-antigen protein Abhydrolase_1 PF00561.20 KKK16167.1 - 3.2e-14 53.2 0.0 1.5e-13 51.0 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KKK16167.1 - 4.4e-07 29.4 0.0 7.4e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KKK16167.1 - 0.0004 21.1 0.0 0.0008 20.1 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.20 KKK16167.1 - 0.09 12.4 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Inhibitor_I53 PF11714.8 KKK16168.1 - 5.3 7.3 7.0 9.3 6.5 0.4 3.4 3 0 0 3 3 3 0 Thrombin inhibitor Madanin Pyridoxal_deC PF00282.19 KKK16169.1 - 2.9e-27 95.4 0.0 5.7e-27 94.4 0.0 1.3 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.21 KKK16169.1 - 0.00037 19.9 0.0 0.00049 19.5 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Hanta_nucleocap PF00846.18 KKK16169.1 - 0.0082 14.6 0.0 0.015 13.8 0.0 1.3 1 0 0 1 1 1 1 Hantavirus nucleocapsid protein SepSecS PF05889.13 KKK16169.1 - 0.012 14.3 0.0 0.02 13.6 0.0 1.2 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS BRK PF07533.16 KKK16169.1 - 0.017 14.7 0.0 0.071 12.7 0.1 2.0 2 0 0 2 2 2 0 BRK domain Proteasome PF00227.26 KKK16170.1 - 1.8e-47 161.3 0.0 2.2e-47 161.0 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.8 KKK16170.1 - 7.4e-14 50.9 2.7 7.4e-14 50.9 2.7 1.8 2 0 0 2 2 2 1 Proteasome beta subunits C terminal Methyltransf_23 PF13489.6 KKK16172.1 - 3.1e-21 75.9 0.0 4.4e-21 75.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKK16172.1 - 3.6e-10 40.4 0.0 1e-09 39.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KKK16172.1 - 3.6e-07 30.8 0.0 1.2e-06 29.2 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KKK16172.1 - 6.3e-07 29.3 0.0 3.4e-06 26.9 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KKK16172.1 - 4.9e-06 27.1 0.0 9.3e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 KKK16172.1 - 0.027 14.2 0.0 0.04 13.7 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_4 PF02390.17 KKK16172.1 - 0.061 12.8 0.0 0.13 11.7 0.0 1.6 1 0 0 1 1 1 0 Putative methyltransferase Ubie_methyltran PF01209.18 KKK16172.1 - 0.08 12.3 0.0 0.25 10.6 0.0 1.9 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family MTS PF05175.14 KKK16172.1 - 0.16 11.5 0.0 0.28 10.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain PrmA PF06325.13 KKK16172.1 - 0.17 11.2 0.0 0.27 10.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) CENP-K PF11802.8 KKK16173.1 - 2.3e-05 24.1 8.2 0.035 13.7 4.6 2.9 2 1 1 3 3 3 2 Centromere-associated protein K Rop-like PF05082.13 KKK16173.1 - 0.43 10.4 4.0 1.3 8.9 0.2 3.0 3 0 0 3 3 3 0 Rop-like DUF4201 PF13870.6 KKK16173.1 - 0.86 9.3 18.4 0.39 10.4 1.4 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4201) Prominin PF05478.11 KKK16173.1 - 3.1 5.7 5.0 4.3 5.2 3.6 1.8 1 1 1 2 2 2 0 Prominin DUF2407 PF10302.9 KKK16173.1 - 4.2 8.0 0.0 4.2 8.0 0.0 3.1 4 0 0 4 4 4 0 DUF2407 ubiquitin-like domain Fib_alpha PF08702.10 KKK16173.1 - 6.1 7.0 15.7 1.2 9.3 1.9 2.5 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family CP12 PF02672.15 KKK16173.1 - 7.4 7.4 6.9 2.4 9.0 0.1 3.1 3 1 1 4 4 4 0 CP12 domain TBCC_N PF16752.5 KKK16173.1 - 8.8 6.8 15.4 1.5 9.3 0.8 3.0 3 0 0 3 3 3 0 Tubulin-specific chaperone C N-terminal domain KH_1 PF00013.29 KKK16174.1 - 9.8e-45 150.2 4.6 1.2e-17 63.4 0.3 3.2 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 KKK16174.1 - 1.5e-11 43.9 3.3 0.01 15.6 0.2 3.2 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 KKK16174.1 - 1e-05 25.3 1.1 0.71 9.8 0.0 3.3 3 0 0 3 3 3 2 KH domain MOEP19 PF16005.5 KKK16174.1 - 0.00025 21.0 0.0 0.01 15.8 0.0 2.5 3 0 0 3 3 3 1 KH-like RNA-binding domain KH_5 PF13184.6 KKK16174.1 - 0.0014 18.7 9.4 0.19 11.9 0.2 3.3 3 0 0 3 3 3 3 NusA-like KH domain Helicase_C PF00271.31 KKK16176.1 - 1e-20 74.1 0.0 2e-17 63.5 0.0 2.8 3 0 0 3 3 3 2 Helicase conserved C-terminal domain DEAD PF00270.29 KKK16176.1 - 3.9e-20 72.4 0.0 9.5e-20 71.1 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase RQC PF09382.10 KKK16176.1 - 2.9e-17 62.5 0.0 6.1e-17 61.4 0.0 1.6 1 0 0 1 1 1 1 RQC domain RecQ_Zn_bind PF16124.5 KKK16176.1 - 4.8e-17 62.5 10.1 4.8e-17 62.5 10.1 2.4 2 0 0 2 2 2 1 RecQ zinc-binding HRDC PF00570.23 KKK16176.1 - 1.3e-08 34.7 0.0 3.7e-08 33.2 0.0 1.8 1 0 0 1 1 1 1 HRDC domain ResIII PF04851.15 KKK16176.1 - 1.2e-05 25.3 0.0 0.00011 22.3 0.0 2.5 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 KKK16176.1 - 0.0003 19.6 0.0 0.00042 19.1 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain WD40 PF00400.32 KKK16177.1 - 2.5e-10 40.8 2.0 0.015 16.2 0.4 3.6 3 1 0 3 3 3 3 WD domain, G-beta repeat Chitin_synth_2 PF03142.15 KKK16178.1 - 1.8e-228 759.5 0.0 3.3e-228 758.6 0.0 1.3 2 0 0 2 2 2 1 Chitin synthase DEK_C PF08766.11 KKK16178.1 - 1.1e-16 60.5 0.4 5.7e-16 58.2 0.7 2.0 2 0 0 2 2 2 1 DEK C terminal domain Glyco_trans_2_3 PF13632.6 KKK16178.1 - 1.6e-13 51.0 1.6 1.6e-13 51.0 1.6 1.8 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Cyt-b5 PF00173.28 KKK16178.1 - 3.1e-13 49.7 0.1 5.6e-07 29.6 0.0 3.1 2 1 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_tranf_2_3 PF13641.6 KKK16178.1 - 1e-11 45.2 0.0 1.2e-10 41.7 0.0 2.3 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Myosin_head PF00063.21 KKK16178.1 - 2.2e-10 39.5 0.0 2e-09 36.3 0.0 2.0 1 1 0 1 1 1 1 Myosin head (motor domain) Glyco_transf_21 PF13506.6 KKK16178.1 - 0.0013 18.2 0.0 0.0043 16.5 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 KKK16178.1 - 0.0063 16.3 0.0 0.36 10.6 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferase family 2 zf-Tim10_DDP PF02953.15 KKK16186.1 - 6.7e-20 70.5 4.4 9.6e-20 70.0 4.4 1.3 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.13 KKK16186.1 - 0.0061 16.3 3.1 0.59 9.8 0.3 2.0 1 1 1 2 2 2 2 Eukaryotic protein of unknown function (DUF842) TAF6_C PF07571.13 KKK16186.1 - 0.047 14.0 0.0 0.079 13.3 0.0 1.3 1 1 0 1 1 1 0 TAF6 C-terminal HEAT repeat domain Arf PF00025.21 KKK16187.1 - 1.8e-25 89.4 0.0 4.2e-25 88.2 0.0 1.7 1 1 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KKK16187.1 - 1.7e-07 31.4 0.0 3.5e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KKK16187.1 - 0.00014 21.5 0.0 0.00022 20.9 0.0 1.3 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 KKK16187.1 - 0.0031 16.9 0.0 0.0062 16.0 0.0 1.5 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 KKK16187.1 - 0.055 12.6 3.5 0.46 9.6 0.1 2.7 2 2 1 3 3 3 0 G-protein alpha subunit ADH_N PF08240.12 KKK16188.1 - 4.6e-25 87.6 1.0 9.4e-25 86.6 1.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KKK16188.1 - 5.6e-19 68.4 0.6 1.1e-18 67.4 0.6 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KKK16188.1 - 0.00079 18.8 1.4 0.0014 17.9 1.4 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Sacchrp_dh_NADP PF03435.18 KKK16188.1 - 0.0027 17.9 0.1 0.0054 17.0 0.1 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Glu_dehyd_C PF16912.5 KKK16188.1 - 0.0032 17.0 0.1 0.024 14.1 0.1 2.0 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 KKK16188.1 - 0.0094 17.0 0.0 0.018 16.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Pep_deformylase PF01327.21 KKK16188.1 - 0.19 11.3 0.0 0.66 9.6 0.0 1.8 2 0 0 2 2 2 0 Polypeptide deformylase Ndc80_HEC PF03801.13 KKK16190.1 - 9.9e-60 200.6 0.3 2.8e-59 199.1 0.0 1.9 2 0 0 2 2 2 1 HEC/Ndc80p family DUF16 PF01519.16 KKK16190.1 - 0.0036 17.8 7.4 0.0036 17.8 7.4 4.0 2 2 1 3 3 3 1 Protein of unknown function DUF16 DUF3818 PF12825.7 KKK16190.1 - 0.058 12.4 19.0 0.069 12.2 4.4 2.3 2 0 0 2 2 2 0 Domain of unknown function in PX-proteins (DUF3818) Filament PF00038.21 KKK16190.1 - 0.078 12.6 47.9 0.2 11.2 22.7 2.8 2 1 0 2 2 2 0 Intermediate filament protein NPV_P10 PF05531.12 KKK16190.1 - 2.5 8.6 14.7 4.1 7.9 0.4 4.4 2 2 2 4 4 4 0 Nucleopolyhedrovirus P10 protein Spc7 PF08317.11 KKK16190.1 - 2.6 6.8 47.8 1.2 8.0 19.7 3.1 2 2 0 2 2 2 0 Spc7 kinetochore protein Cep57_CLD PF14073.6 KKK16190.1 - 4.2 7.4 41.8 0.27 11.3 19.7 2.5 2 0 0 2 2 2 0 Centrosome localisation domain of Cep57 Prominin PF05478.11 KKK16190.1 - 5.7 4.8 24.0 0.19 9.7 6.8 2.5 2 1 0 2 2 2 0 Prominin TraF_2 PF13729.6 KKK16190.1 - 7.7 5.8 9.0 0.55 9.6 0.8 2.7 2 1 1 3 3 3 0 F plasmid transfer operon, TraF, protein Pex14_N PF04695.13 KKK16191.1 - 2.4e-43 148.5 0.2 2.4e-43 148.5 0.2 4.4 3 2 1 4 4 4 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF1043 PF06295.12 KKK16191.1 - 0.0089 16.0 1.1 0.28 11.2 0.3 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1043) Baculo_PEP_C PF04513.12 KKK16191.1 - 0.18 11.8 2.6 0.64 10.1 2.7 1.8 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Golgin_A5 PF09787.9 KKK16191.1 - 2.3 7.6 19.6 0.023 14.2 1.1 3.0 3 0 0 3 3 3 0 Golgin subfamily A member 5 FCH PF00611.23 KKK16192.1 - 1.3e-14 54.2 0.0 8.8e-14 51.6 0.0 2.4 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.28 KKK16192.1 - 3.8e-12 45.6 0.0 8.4e-12 44.5 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KKK16192.1 - 1.1e-10 41.2 0.0 2.4e-10 40.1 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KKK16192.1 - 4.3e-10 39.1 0.0 1.7e-09 37.2 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain Transcrip_act PF04949.13 KKK16192.1 - 0.13 12.1 1.5 10 6.0 0.1 2.3 2 0 0 2 2 2 0 Transcriptional activator TTL PF03133.15 KKK16193.1 - 9.9e-56 189.0 0.0 1.5e-55 188.4 0.0 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family SurE PF01975.17 KKK16193.1 - 3e-50 170.7 0.0 4.4e-50 170.2 0.0 1.2 1 0 0 1 1 1 1 Survival protein SurE ATPgrasp_YheCD PF14398.6 KKK16193.1 - 4e-05 23.0 0.0 0.00012 21.4 0.0 1.7 2 0 0 2 2 2 1 YheC/D like ATP-grasp Dala_Dala_lig_C PF07478.13 KKK16193.1 - 0.1 12.1 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus Not1 PF04054.15 KKK16194.1 - 5.1e-140 466.6 0.1 1.5e-139 465.0 0.0 1.9 2 0 0 2 2 2 1 CCR4-Not complex component, Not1 CNOT1_CAF1_bind PF16415.5 KKK16194.1 - 7.9e-96 319.8 0.3 1.8e-95 318.6 0.3 1.6 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain Seipin PF06775.14 KKK16194.1 - 1.4e-61 208.1 2.3 2.8e-61 207.1 2.3 1.5 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) DUF3819 PF12842.7 KKK16194.1 - 2.3e-52 176.8 2.7 1.2e-51 174.5 1.4 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3819) CNOT1_TTP_bind PF16417.5 KKK16194.1 - 2.8e-40 137.5 0.0 7.7e-40 136.1 0.0 1.7 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 TTP binding domain CNOT1_HEAT PF16418.5 KKK16194.1 - 1.7e-31 109.3 0.0 8e-31 107.1 0.0 2.2 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 1 HEAT repeat SCO1-SenC PF02630.14 KKK16195.1 - 1.5e-47 160.9 0.1 2.5e-47 160.1 0.1 1.4 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.21 KKK16195.1 - 0.00022 21.1 0.0 0.00055 19.9 0.0 1.7 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 KKK16195.1 - 0.054 13.8 0.0 0.097 13.0 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like Redoxin PF08534.10 KKK16195.1 - 0.15 11.7 0.0 0.55 9.9 0.0 2.0 1 1 0 1 1 1 0 Redoxin Yae1_N PF09811.9 KKK16198.1 - 0.058 13.1 0.3 0.11 12.2 0.3 1.4 1 0 0 1 1 1 0 Essential protein Yae1, N terminal MRVI1 PF05781.12 KKK16200.1 - 0.28 9.8 0.0 0.29 9.8 0.0 1.0 1 0 0 1 1 1 0 MRVI1 protein Radical_SAM_C PF16199.5 KKK16201.1 - 8.5e-33 112.2 0.0 1.9e-32 111.1 0.0 1.6 1 0 0 1 1 1 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 KKK16201.1 - 2.5e-20 73.5 0.1 1e-19 71.5 0.0 2.0 2 0 0 2 2 2 1 Radical SAM superfamily Acetyltransf_1 PF00583.25 KKK16201.1 - 1.9e-10 41.0 0.0 3.5e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KKK16201.1 - 9e-06 25.6 0.0 3.5e-05 23.8 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain CoA_binding PF02629.19 KKK16202.1 - 2.2e-26 92.4 4.0 3.1e-26 91.9 1.5 2.1 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 KKK16202.1 - 4.1e-23 81.9 0.2 6.8e-23 81.2 0.2 1.4 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 KKK16202.1 - 2.2e-07 30.8 0.1 4.1e-07 29.9 0.1 1.5 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 KKK16202.1 - 0.00038 20.9 0.1 0.00087 19.8 0.1 1.6 1 0 0 1 1 1 1 CoA binding domain ABC_tran PF00005.27 KKK16203.1 - 2.5e-12 47.5 0.0 4.3e-12 46.7 0.0 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KKK16203.1 - 0.00014 21.4 0.1 0.00018 21.0 0.1 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 KKK16203.1 - 0.014 15.7 1.7 0.25 11.6 1.5 2.4 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit ThiF PF00899.21 KKK16204.1 - 2.3e-31 109.0 0.0 3e-31 108.6 0.0 1.1 1 0 0 1 1 1 1 ThiF family Ytp1 PF10355.9 KKK16205.1 - 1.5e-72 244.1 16.8 1.5e-72 244.1 16.8 2.3 2 1 0 2 2 2 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 KKK16205.1 - 4.7e-33 113.1 1.1 4.7e-33 113.1 1.1 3.0 3 0 0 3 3 3 1 Domain of unknown function (DUF2427) Zip PF02535.22 KKK16205.1 - 0.00012 21.5 1.9 0.15 11.3 0.0 2.7 2 0 0 2 2 2 2 ZIP Zinc transporter ExoD PF06055.12 KKK16205.1 - 0.0082 15.5 0.3 0.0082 15.5 0.3 2.8 4 0 0 4 4 4 1 Exopolysaccharide synthesis, ExoD DUF3180 PF11377.8 KKK16205.1 - 0.067 13.3 7.3 3.3 7.8 5.3 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF3180) RFX_DNA_binding PF02257.15 KKK16206.1 - 8.7e-28 96.8 0.2 2e-27 95.6 0.2 1.7 1 0 0 1 1 1 1 RFX DNA-binding domain YL1 PF05764.13 KKK16207.1 - 0.00035 20.8 9.5 0.00035 20.8 9.5 2.2 2 0 0 2 2 2 1 YL1 nuclear protein CDC45 PF02724.14 KKK16207.1 - 0.00052 18.4 7.1 0.001 17.5 7.1 1.4 1 0 0 1 1 1 1 CDC45-like protein SDA1 PF05285.12 KKK16207.1 - 0.081 12.3 8.8 0.15 11.5 8.8 1.4 1 0 0 1 1 1 0 SDA1 MFAP1 PF06991.11 KKK16207.1 - 0.14 12.0 9.7 0.069 13.0 3.8 2.3 2 0 0 2 2 2 0 Microfibril-associated/Pre-mRNA processing FAM176 PF14851.6 KKK16207.1 - 1.2 8.8 7.9 3.8 7.2 7.9 1.9 1 0 0 1 1 1 0 FAM176 family PPP4R2 PF09184.11 KKK16207.1 - 1.5 8.3 11.9 2.8 7.5 11.9 1.4 1 0 0 1 1 1 0 PPP4R2 NOA36 PF06524.12 KKK16207.1 - 2.5 7.4 23.3 4.4 6.5 23.3 1.3 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 KKK16207.1 - 2.7 6.0 21.5 4.2 5.3 21.5 1.2 1 0 0 1 1 1 0 DNA polymerase phi Tom22 PF04281.13 KKK16207.1 - 3.2 7.6 11.5 8.1 6.2 11.5 1.7 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 BUD22 PF09073.10 KKK16207.1 - 3.5 6.8 15.9 7.1 5.9 15.9 1.5 1 0 0 1 1 1 0 BUD22 DUF4407 PF14362.6 KKK16207.1 - 5.4 6.3 5.2 18 4.5 0.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Nop14 PF04147.12 KKK16207.1 - 5.9 5.0 19.0 0.094 10.9 12.0 1.5 2 0 0 2 2 2 0 Nop14-like family RXT2_N PF08595.11 KKK16207.1 - 6.4 6.8 12.0 16 5.5 12.0 1.7 1 0 0 1 1 1 0 RXT2-like, N-terminal RRN3 PF05327.11 KKK16207.1 - 6.5 5.2 13.2 10 4.6 13.2 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Vfa1 PF08432.10 KKK16207.1 - 7.4 6.9 8.0 0.24 11.7 1.7 1.7 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 GCIP PF13324.6 KKK16207.1 - 8.6 5.9 9.0 16 5.0 9.0 1.4 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting SURF2 PF05477.11 KKK16207.1 - 8.8 5.9 8.2 58 3.3 8.1 2.1 1 1 0 1 1 1 0 Surfeit locus protein 2 (SURF2) gag-asp_proteas PF13975.6 KKK16208.1 - 0.0046 17.5 0.0 0.0085 16.6 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.20 KKK16208.1 - 0.036 14.4 0.0 0.064 13.6 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease SF3A2 PF16835.5 KKK16209.1 - 4.6e-24 84.6 2.1 1.3e-23 83.2 0.0 2.2 1 1 1 2 2 2 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) zf-met PF12874.7 KKK16209.1 - 9.7e-06 25.8 0.5 1.8e-05 24.9 0.5 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type PRP4 PF08799.11 KKK16209.1 - 0.052 13.1 1.5 0.1 12.2 1.5 1.5 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like Pkinase PF00069.25 KKK16210.1 - 8.4e-56 189.2 0.0 1.3e-54 185.4 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK16210.1 - 3.9e-25 88.6 0.5 1.1e-19 70.7 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 KKK16210.1 - 5.9e-06 25.5 0.0 8.4e-06 25.0 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KKK16210.1 - 0.0002 21.4 0.2 0.024 14.5 0.2 2.5 1 1 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KKK16210.1 - 0.00041 19.8 0.0 0.00098 18.5 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KKK16210.1 - 0.00056 19.3 0.3 0.0015 17.9 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.11 KKK16210.1 - 0.0052 15.9 0.0 0.0086 15.2 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 FTA2 PF13095.6 KKK16210.1 - 0.022 14.4 0.2 4.5 6.8 0.1 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 KKK16210.1 - 0.068 11.9 0.0 0.13 11.0 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase TFIIA PF03153.13 KKK16210.1 - 0.093 12.7 9.2 0.14 12.1 9.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit NFACT-C PF11923.8 KKK16210.1 - 0.094 12.6 0.2 0.2 11.6 0.2 1.5 1 0 0 1 1 1 0 NFACT protein C-terminal domain PA28_alpha PF02251.18 KKK16210.1 - 0.16 12.1 0.1 1 9.5 0.0 2.3 2 0 0 2 2 2 0 Proteasome activator pa28 alpha subunit RIO1 PF01163.22 KKK16210.1 - 0.23 11.0 1.2 0.57 9.8 0.0 2.0 2 0 0 2 2 2 0 RIO1 family CAP_GLY PF01302.25 KKK16211.1 - 5.4e-15 55.2 0.2 1.4e-14 53.8 0.2 1.6 1 0 0 1 1 1 1 CAP-Gly domain zf-U1 PF06220.12 KKK16211.1 - 4.1e-06 26.5 0.1 7e-06 25.7 0.1 1.4 1 0 0 1 1 1 1 U1 zinc finger LRR_9 PF14580.6 KKK16211.1 - 0.00066 19.2 0.0 0.035 13.6 0.0 2.4 1 1 1 2 2 2 2 Leucine-rich repeat CCDC84 PF14968.6 KKK16211.1 - 0.0075 15.9 0.2 0.011 15.3 0.2 1.2 1 0 0 1 1 1 1 Coiled coil protein 84 IF2_assoc PF08364.11 KKK16211.1 - 0.17 12.2 1.3 0.67 10.3 1.3 2.1 1 0 0 1 1 1 0 Bacterial translation initiation factor IF-2 associated region LRR_4 PF12799.7 KKK16211.1 - 0.19 12.2 0.4 4.5 7.8 0.3 2.6 1 1 2 3 3 3 0 Leucine Rich repeats (2 copies) ABC_tran_Xtn PF12848.7 KKK16211.1 - 2.1 8.4 6.1 0.31 11.1 1.0 2.3 2 0 0 2 2 2 0 ABC transporter Tim54 PF11711.8 KKK16212.1 - 1.9e-127 425.1 0.1 4.8e-106 354.7 0.1 2.0 1 1 1 2 2 2 2 Inner membrane protein import complex subunit Tim54 Fungal_trans PF04082.18 KKK16213.1 - 8.6e-16 57.8 5.8 1.4e-15 57.0 5.8 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK16213.1 - 4e-08 33.2 8.5 4e-08 33.2 8.5 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Rox3 PF08633.10 KKK16214.1 - 1.8e-63 214.6 1.5 1.8e-63 214.6 1.5 1.8 2 0 0 2 2 2 1 Rox3 mediator complex subunit PBP1_TM PF14812.6 KKK16214.1 - 0.056 13.8 3.0 0.11 12.9 3.0 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Fungal_trans PF04082.18 KKK16215.1 - 1.2e-18 67.1 0.2 1.8e-18 66.5 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK16215.1 - 1.1e-09 38.2 12.3 2.1e-09 37.4 12.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MMS22L_C PF14911.6 KKK16215.1 - 0.1 11.6 0.2 0.26 10.3 0.1 1.6 2 0 0 2 2 2 0 S-phase genomic integrity recombination mediator, C-terminal IFP_35_N PF07334.13 KKK16215.1 - 0.11 12.6 0.4 0.35 11.0 0.4 1.8 1 0 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Glyco_hydro_114 PF03537.13 KKK16241.1 - 7.1e-84 280.7 0.6 8.6e-84 280.5 0.6 1.1 1 0 0 1 1 1 1 Glycoside-hydrolase family GH114 Acyl-CoA_dh_1 PF00441.24 KKK16249.1 - 1.7e-37 128.9 7.3 2.9e-37 128.2 7.3 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KKK16249.1 - 2.5e-27 95.8 0.8 6.5e-27 94.4 0.0 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KKK16249.1 - 5.6e-24 84.2 0.0 1.2e-23 83.1 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KKK16249.1 - 1e-16 61.4 4.3 1.9e-16 60.5 4.3 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Metallophos PF00149.28 KKK16249.1 - 1.2e-08 35.7 0.3 2e-08 35.0 0.3 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase HpaB_N PF11794.8 KKK16249.1 - 0.024 14.3 0.0 0.061 13.0 0.0 1.7 1 0 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal Senescence PF06911.12 KKK16250.1 - 1.3e-53 182.1 3.2 1.9e-53 181.5 3.2 1.3 1 0 0 1 1 1 1 Senescence-associated protein DUF3082 PF11282.8 KKK16250.1 - 0.043 14.1 0.0 0.1 12.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3082) Pkinase PF00069.25 KKK16251.1 - 2.2e-64 217.4 0.0 3.9e-64 216.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK16251.1 - 9e-36 123.5 0.0 2.9e-30 105.4 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KKK16251.1 - 9.5e-07 28.4 0.1 0.0013 18.2 0.0 2.2 1 1 1 2 2 2 2 Kinase-like APH PF01636.23 KKK16251.1 - 0.00014 21.9 0.1 0.00047 20.2 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 KKK16251.1 - 0.0019 17.9 0.0 0.0035 17.0 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 KKK16251.1 - 0.012 14.6 0.1 0.02 13.8 0.1 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 KKK16251.1 - 0.024 14.0 0.2 0.055 12.8 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Peptidase_M28 PF04389.17 KKK16252.1 - 1.7e-40 138.8 0.1 3.3e-40 137.9 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 KKK16252.1 - 5.5e-12 45.5 1.0 1.2e-11 44.4 1.0 1.6 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 KKK16252.1 - 0.00015 21.6 0.0 0.0011 18.7 0.0 2.4 2 1 0 2 2 2 1 Peptidase family M20/M25/M40 Nicastrin PF05450.15 KKK16252.1 - 0.085 12.3 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 Nicastrin Peptidase_M42 PF05343.14 KKK16252.1 - 0.16 11.0 0.0 0.9 8.5 0.0 2.1 2 0 0 2 2 2 0 M42 glutamyl aminopeptidase MGC-24 PF05283.11 KKK16253.1 - 0.99 9.9 28.4 2.3 8.7 28.4 1.7 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Dicty_REP PF05086.12 KKK16253.1 - 2.7 5.9 13.5 4 5.3 13.5 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Cu_amine_oxid PF01179.20 KKK16254.1 - 1.1e-157 525.1 0.4 2.7e-156 520.6 0.4 2.0 1 1 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 KKK16254.1 - 0.00064 20.1 0.0 0.0014 19.0 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.16 KKK16254.1 - 0.014 15.6 0.0 0.026 14.7 0.0 1.4 1 0 0 1 1 1 0 Copper amine oxidase, N2 domain ABC1 PF03109.16 KKK16255.1 - 3.4e-33 114.3 0.0 2.3e-32 111.7 0.0 2.4 3 0 0 3 3 3 1 ABC1 family Mannosyl_trans3 PF11051.8 KKK16256.1 - 1.6e-63 214.7 0.0 4.9e-37 127.8 0.0 2.1 1 1 1 2 2 2 2 Mannosyltransferase putative GIDA PF01134.22 KKK16257.1 - 4e-154 513.4 0.0 4.9e-154 513.2 0.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc PF13932.6 KKK16257.1 - 4.2e-67 226.4 0.1 5.7e-67 226.0 0.1 1.2 1 0 0 1 1 1 1 GidA associated domain Pyr_redox_2 PF07992.14 KKK16257.1 - 5e-06 26.0 0.4 8.8e-06 25.2 0.4 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KKK16257.1 - 5.3e-06 26.1 1.1 8.5e-06 25.4 1.1 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 KKK16257.1 - 0.00067 19.0 0.2 0.002 17.4 0.2 1.7 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 KKK16257.1 - 0.0019 17.4 1.7 0.0019 17.4 1.7 1.8 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 KKK16257.1 - 0.018 13.8 0.6 0.17 10.6 0.5 2.2 2 0 0 2 2 2 0 HI0933-like protein Lycopene_cycl PF05834.12 KKK16257.1 - 0.045 12.8 0.2 0.096 11.7 0.2 1.5 1 1 0 1 1 1 0 Lycopene cyclase protein DAO PF01266.24 KKK16257.1 - 0.19 11.3 4.0 4 6.9 0.0 2.7 3 0 0 3 3 3 0 FAD dependent oxidoreductase Gti1_Pac2 PF09729.9 KKK16258.1 - 8.2e-63 211.8 0.0 2.2e-62 210.4 0.0 1.6 2 0 0 2 2 2 1 Gti1/Pac2 family MMM1 PF10296.9 KKK16259.1 - 9.1e-133 442.4 0.0 1.1e-132 442.1 0.0 1.0 1 0 0 1 1 1 1 Maintenance of mitochondrial morphology protein 1 ARD PF03079.14 KKK16260.1 - 1.1e-44 152.3 0.3 1.3e-44 152.1 0.3 1.0 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.11 KKK16260.1 - 4.9e-10 39.0 0.0 8.5e-10 38.2 0.0 1.4 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 KKK16260.1 - 5.9e-07 29.5 0.0 8.7e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain Myb_DNA-bind_7 PF15963.5 KKK16261.1 - 1.1e-28 98.9 0.2 1.1e-28 98.9 0.2 2.1 1 1 1 2 2 2 1 Myb DNA-binding like Myb_DNA-binding PF00249.31 KKK16261.1 - 4.6e-06 26.7 0.0 9.1e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain SARAF PF06682.12 KKK16262.1 - 2e-66 224.9 0.0 2.7e-66 224.5 0.0 1.1 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis UreF PF01730.16 KKK16263.1 - 6.8e-24 85.0 0.3 1e-23 84.3 0.3 1.2 1 0 0 1 1 1 1 UreF Sugarporin_N PF11471.8 KKK16263.1 - 0.086 12.8 0.7 0.086 12.8 0.7 2.3 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension BRE1 PF08647.11 KKK16264.1 - 1.5e-28 98.7 12.7 1.5e-28 98.7 12.7 7.2 5 3 2 7 7 6 1 BRE1 E3 ubiquitin ligase zf-C3HC4_3 PF13920.6 KKK16264.1 - 1.5e-09 37.6 7.9 2.7e-09 36.7 7.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KKK16264.1 - 4.5e-09 36.0 8.3 8e-09 35.2 8.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KKK16264.1 - 4.2e-08 32.9 6.6 7.2e-08 32.2 6.6 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 KKK16264.1 - 7e-08 32.2 10.2 1.3e-07 31.4 10.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KKK16264.1 - 1.1e-07 31.8 5.9 2.5e-07 30.6 5.9 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 KKK16264.1 - 2.7e-07 30.8 8.6 4.6e-07 30.1 8.6 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 KKK16264.1 - 7.8e-06 25.8 10.5 1.4e-05 24.9 10.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 KKK16264.1 - 0.0017 18.6 5.7 0.0086 16.3 5.5 2.2 2 0 0 2 2 2 1 RING-H2 zinc finger domain HAP1_N PF04849.13 KKK16264.1 - 0.0018 17.6 22.8 0.0018 17.6 22.8 5.3 2 2 2 5 5 5 1 HAP1 N-terminal conserved region KxDL PF10241.9 KKK16264.1 - 0.0024 18.1 3.9 0.0024 18.1 3.9 6.0 4 2 1 6 6 6 1 Uncharacterized conserved protein Lebercilin PF15619.6 KKK16264.1 - 0.0041 16.8 6.9 0.0041 16.8 6.9 5.3 4 2 1 5 5 4 2 Ciliary protein causing Leber congenital amaurosis disease Meth_synt_1 PF08267.12 KKK16264.1 - 0.0049 16.4 0.4 0.0049 16.4 0.4 3.0 3 1 0 4 4 4 1 Cobalamin-independent synthase, N-terminal domain zf-C3HC4_4 PF15227.6 KKK16264.1 - 0.0064 16.6 6.4 0.012 15.7 6.4 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING DUF1272 PF06906.11 KKK16264.1 - 0.01 15.9 6.0 0.02 15.0 6.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1272) zf-RING_4 PF14570.6 KKK16264.1 - 0.023 14.5 7.3 0.19 11.6 8.0 2.1 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain CP12 PF02672.15 KKK16264.1 - 0.32 11.8 0.1 0.32 11.8 0.1 4.7 4 1 0 5 5 1 0 CP12 domain zf-RING_10 PF16685.5 KKK16264.1 - 0.33 11.1 9.0 0.12 12.5 6.0 1.9 2 0 0 2 2 1 0 zinc RING finger of MSL2 zf-UDP PF14569.6 KKK16264.1 - 0.45 10.7 4.4 1.1 9.4 4.4 1.7 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-C2HC_2 PF13913.6 KKK16264.1 - 0.93 9.5 7.3 0.97 9.4 2.7 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Zn_ribbon_17 PF17120.5 KKK16264.1 - 1.2 8.8 4.6 2.3 7.9 4.6 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-Nse PF11789.8 KKK16264.1 - 1.3 8.9 5.2 2.9 7.8 5.2 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit FYVE PF01363.21 KKK16264.1 - 1.5 9.0 11.7 23 5.2 11.7 2.5 1 1 1 2 2 2 0 FYVE zinc finger DUF5340 PF17275.2 KKK16264.1 - 10 6.4 9.7 0.34 11.1 0.3 3.4 3 0 0 3 3 3 0 Family of unknown function (DUF5340) Cu-oxidase_3 PF07732.15 KKK16278.1 - 7.7e-41 138.8 3.4 7.7e-41 138.8 3.4 3.5 3 1 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 KKK16278.1 - 1.2e-39 135.2 13.9 9.1e-38 129.1 3.5 2.9 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.22 KKK16278.1 - 1.9e-39 135.3 0.8 2.2e-36 125.4 0.1 3.0 2 1 1 3 3 3 2 Multicopper oxidase Med12-PQL PF12144.8 KKK16278.1 - 0.09 12.7 0.1 0.18 11.6 0.1 1.4 1 0 0 1 1 1 0 Eukaryotic Mediator 12 catenin-binding domain Alpha-amylase PF00128.24 KKK16279.1 - 1.8e-65 221.7 0.8 2.4e-65 221.3 0.8 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain CBM_20 PF00686.19 KKK16279.1 - 9.8e-34 115.1 0.1 2.4e-33 113.9 0.1 1.7 1 0 0 1 1 1 1 Starch binding domain DUF1966 PF09260.11 KKK16279.1 - 3.2e-32 110.7 0.2 6.6e-32 109.7 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) TPR_11 PF13414.6 KKK16280.1 - 1.3e-08 34.3 0.5 0.057 13.1 0.0 3.6 2 1 1 3 3 3 3 TPR repeat TPR_2 PF07719.17 KKK16280.1 - 3.4e-05 23.6 15.5 0.0037 17.3 0.0 6.4 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.28 KKK16280.1 - 9.8e-05 22.0 10.9 0.03 14.2 0.0 5.6 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.6 KKK16280.1 - 0.00064 19.9 0.1 0.24 11.8 0.1 3.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 KKK16280.1 - 0.01 16.0 1.3 10 6.6 0.0 4.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Plug_translocon PF10559.9 KKK16280.1 - 0.012 15.4 0.1 0.028 14.3 0.1 1.6 1 0 0 1 1 1 0 Plug domain of Sec61p TPR_7 PF13176.6 KKK16280.1 - 0.013 15.5 4.9 0.58 10.3 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 KKK16280.1 - 0.53 10.6 9.0 1.3 9.4 0.7 4.4 3 2 1 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 KKK16280.1 - 1.3 9.6 16.4 0.26 11.8 1.6 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat Ank_4 PF13637.6 KKK16281.1 - 3.7e-12 46.5 1.5 1.8e-08 34.7 0.1 4.3 3 1 1 4 4 4 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KKK16281.1 - 3.5e-06 27.5 0.2 0.013 16.1 0.1 3.4 2 1 3 5 5 5 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KKK16281.1 - 0.00057 20.1 2.0 0.2 12.3 0.1 4.2 4 1 0 4 4 4 1 Ankyrin repeat Ank_5 PF13857.6 KKK16281.1 - 0.0039 17.5 1.4 0.16 12.3 0.1 3.2 3 0 0 3 3 3 1 Ankyrin repeats (many copies) KilA-N PF04383.13 KKK16281.1 - 0.006 16.4 0.3 0.045 13.6 0.3 2.3 1 1 0 1 1 1 1 KilA-N domain Baculo_PEP_C PF04513.12 KKK16281.1 - 0.013 15.5 1.1 0.022 14.8 0.3 1.7 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus TFR_dimer PF04253.15 KKK16281.1 - 0.2 11.7 1.0 0.59 10.3 1.0 1.7 1 0 0 1 1 1 0 Transferrin receptor-like dimerisation domain IMD PF08397.11 KKK16281.1 - 0.42 10.0 2.8 0.8 9.0 2.8 1.4 1 0 0 1 1 1 0 IRSp53/MIM homology domain Ank PF00023.30 KKK16281.1 - 1.1 9.8 2.7 35 5.1 0.1 3.7 3 0 0 3 3 3 0 Ankyrin repeat HAUS-augmin3 PF14932.6 KKK16281.1 - 5.2 6.6 8.9 3.6 7.1 3.7 2.2 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 Sugar_tr PF00083.24 KKK16282.1 - 7.4e-38 130.6 23.1 1.4e-36 126.3 23.1 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKK16282.1 - 8.5e-29 100.6 53.3 2.4e-27 95.8 34.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily PGAP1 PF07819.13 KKK16283.1 - 4.6e-90 301.4 0.0 7.7e-90 300.6 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 KKK16283.1 - 5.7e-06 27.1 0.1 1.4e-05 25.8 0.1 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Palm_thioest PF02089.15 KKK16283.1 - 0.00024 21.0 0.0 0.0004 20.3 0.0 1.4 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_1 PF00561.20 KKK16283.1 - 0.00096 18.9 0.0 0.0026 17.5 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF676 PF05057.14 KKK16283.1 - 0.0027 17.2 0.0 0.0052 16.3 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Esterase PF00756.20 KKK16283.1 - 0.0063 16.2 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.8 KKK16283.1 - 0.014 14.7 0.0 0.029 13.6 0.0 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 LCAT PF02450.15 KKK16283.1 - 0.08 12.1 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Lipase_3 PF01764.25 KKK16283.1 - 0.13 12.2 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) Oxidored_q4 PF00507.19 KKK16284.1 - 0.15 12.3 4.1 0.46 10.7 0.1 2.8 3 0 0 3 3 3 0 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 ResIII PF04851.15 KKK16286.1 - 2.4e-25 89.5 0.1 8.8e-23 81.2 0.0 3.2 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KKK16286.1 - 3.7e-15 56.2 0.0 3.6e-14 53.1 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KKK16286.1 - 4e-12 46.2 0.0 4.5e-11 42.8 0.0 2.4 2 1 0 2 2 2 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 KKK16286.1 - 8.1e-07 28.9 0.0 3.1e-06 27.0 0.0 1.9 2 0 0 2 2 2 1 SWI2/SNF2 ATPase DUF2075 PF09848.9 KKK16286.1 - 0.0051 16.1 0.2 0.013 14.7 0.0 1.7 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) FAD_binding_3 PF01494.19 KKK16287.1 - 4.1e-15 55.9 0.1 4.8e-10 39.2 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain FAD_binding_2 PF00890.24 KKK16287.1 - 1.7e-06 27.4 1.0 1.7e-06 27.4 1.0 1.6 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 KKK16287.1 - 3.3e-06 27.2 0.4 1e-05 25.6 0.4 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KKK16287.1 - 5.5e-06 26.9 0.6 3.5e-05 24.3 0.0 2.4 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KKK16287.1 - 7.4e-06 25.4 0.4 2.3e-05 23.8 0.4 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KKK16287.1 - 2.1e-05 23.4 0.5 0.00029 19.7 0.1 2.0 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.24 KKK16287.1 - 2.2e-05 24.2 2.3 0.0027 17.4 2.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 KKK16287.1 - 0.00083 18.8 0.2 0.0017 17.8 0.2 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 KKK16287.1 - 0.0023 17.1 0.2 0.0061 15.7 0.2 1.7 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 KKK16287.1 - 0.0026 17.1 0.4 0.0041 16.4 0.4 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KKK16287.1 - 0.0066 15.3 2.0 0.15 10.9 0.1 2.1 2 0 0 2 2 2 1 Tryptophan halogenase Thi4 PF01946.17 KKK16287.1 - 0.0089 15.3 0.1 0.018 14.3 0.1 1.4 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.12 KKK16287.1 - 0.039 13.0 2.2 0.061 12.4 0.3 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein 3HCDH_N PF02737.18 KKK16287.1 - 0.11 12.3 0.2 0.19 11.6 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 KKK16287.1 - 0.13 11.5 0.1 0.25 10.6 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain SnAPC_2_like PF11035.8 KKK16288.1 - 0.03 14.5 0.1 0.14 12.3 0.0 2.0 2 0 0 2 2 2 0 Small nuclear RNA activating complex subunit 2, SNAP190 Myb RXT2_N PF08595.11 KKK16288.1 - 6 6.9 6.7 0.57 10.2 1.5 1.9 2 0 0 2 2 2 0 RXT2-like, N-terminal SWIRM PF04433.17 KKK16289.1 - 2.7e-32 110.9 0.1 6e-32 109.8 0.1 1.6 1 0 0 1 1 1 1 SWIRM domain SWIRM-assoc_1 PF16495.5 KKK16289.1 - 9.3e-31 105.6 10.9 2.4e-30 104.3 10.9 1.7 1 0 0 1 1 1 1 SWIRM-associated region 1 Myb_DNA-binding PF00249.31 KKK16289.1 - 2.9e-08 33.8 0.0 7.3e-08 32.5 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KKK16289.1 - 9.5e-07 29.0 0.0 2.5e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Pkinase_fungal PF17667.1 KKK16289.1 - 0.17 10.6 2.3 0.31 9.7 2.3 1.3 1 0 0 1 1 1 0 Fungal protein kinase ZZ PF00569.17 KKK16289.1 - 0.42 10.5 4.8 2.5 8.0 4.8 2.1 1 1 0 1 1 1 0 Zinc finger, ZZ type DUF4192 PF13830.6 KKK16289.1 - 1 9.3 9.5 2.2 8.2 9.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) Methyltransf_10 PF05971.12 KKK16290.1 - 2.1e-68 230.9 0.0 2.8e-68 230.5 0.0 1.1 1 0 0 1 1 1 1 RNA methyltransferase MTS PF05175.14 KKK16290.1 - 0.00042 19.9 0.0 0.00077 19.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain PLDc_2 PF13091.6 KKK16291.1 - 2e-14 53.6 0.1 4.1e-06 26.7 0.0 3.5 3 0 0 3 3 3 3 PLD-like domain PLDc PF00614.22 KKK16291.1 - 3.7e-14 52.2 2.8 3.8e-07 30.0 0.1 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif NMD3 PF04981.13 KKK16292.1 - 1e-77 260.9 3.2 1.3e-77 260.5 3.2 1.2 1 0 0 1 1 1 1 NMD3 family DZR PF12773.7 KKK16292.1 - 0.38 10.8 7.9 69 3.6 7.9 2.8 1 1 0 1 1 1 0 Double zinc ribbon DUF35_N PF12172.8 KKK16292.1 - 0.77 9.7 11.5 1.6 8.6 0.1 3.4 4 0 0 4 4 4 0 Rubredoxin-like zinc ribbon domain (DUF35_N) FYVE PF01363.21 KKK16292.1 - 5.1 7.3 6.6 11 6.2 3.4 2.6 2 1 0 2 2 2 0 FYVE zinc finger Dehydrin PF00257.19 KKK16293.1 - 0.00016 22.2 4.6 0.00016 22.2 4.6 1.8 2 0 0 2 2 2 1 Dehydrin Rick_17kDa_Anti PF05433.15 KKK16293.1 - 0.0017 18.2 20.6 0.0031 17.3 20.6 1.4 1 0 0 1 1 1 1 Glycine zipper 2TM domain DUF2076 PF09849.9 KKK16293.1 - 0.013 15.5 16.2 0.013 15.5 16.2 2.9 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) DUF533 PF04391.12 KKK16293.1 - 0.1 12.2 3.9 0.17 11.4 3.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF533) DUF755 PF05501.11 KKK16293.1 - 0.8 10.0 19.6 1.3 9.3 19.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF755) RuBisCO_large PF00016.20 KKK16293.1 - 0.82 8.8 6.5 1.1 8.4 6.5 1.1 1 0 0 1 1 1 0 Ribulose bisphosphate carboxylase large chain, catalytic domain Fungal_trans_2 PF11951.8 KKK16294.1 - 1.5e-06 27.3 0.1 2.2e-06 26.7 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK16294.1 - 0.0013 18.8 0.8 0.0013 18.8 0.8 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain UAA PF08449.11 KKK16295.1 - 4.9e-41 140.9 12.7 1.3e-40 139.5 12.7 1.6 1 1 0 1 1 1 1 UAA transporter family Nuc_sug_transp PF04142.15 KKK16295.1 - 2.7e-06 26.8 1.6 0.019 14.1 0.1 2.3 2 0 0 2 2 2 2 Nucleotide-sugar transporter EamA PF00892.20 KKK16295.1 - 3.5e-05 24.0 10.2 3.5e-05 24.0 10.2 3.4 3 1 0 3 3 3 2 EamA-like transporter family Steroid_dh PF02544.16 KKK16296.1 - 4.3e-13 49.5 0.5 1.1e-12 48.2 0.3 1.8 1 1 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase Rotamase_3 PF13616.6 KKK16297.1 - 7.4e-15 55.5 0.0 1.5e-14 54.5 0.0 1.6 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.21 KKK16297.1 - 4.7e-13 49.9 0.0 7.2e-13 49.3 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 KKK16297.1 - 7.9e-05 23.5 0.0 0.00012 22.9 0.0 1.3 1 1 0 1 1 1 1 PPIC-type PPIASE domain 2OG-FeII_Oxy_2 PF13532.6 KKK16298.1 - 1e-11 45.4 0.0 3.4e-11 43.7 0.0 1.7 1 1 1 2 2 2 1 2OG-Fe(II) oxygenase superfamily Ras PF00071.22 KKK16299.1 - 6.5e-57 191.6 0.0 7.8e-57 191.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KKK16299.1 - 2e-34 118.4 0.0 2.8e-34 117.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKK16299.1 - 1.3e-14 54.1 0.0 2.2e-14 53.3 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KKK16299.1 - 4.6e-05 22.9 0.0 5.5e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KKK16299.1 - 5.2e-05 22.9 0.0 8.1e-05 22.2 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KKK16299.1 - 8.7e-05 22.6 0.0 0.00014 21.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KKK16299.1 - 0.00094 19.6 0.0 0.0013 19.1 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 KKK16299.1 - 0.11 12.3 0.0 1.9 8.3 0.0 2.3 3 0 0 3 3 3 0 RsgA GTPase Thiolase_N PF00108.23 KKK16325.1 - 9.4e-77 257.9 0.1 1.6e-76 257.1 0.1 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KKK16325.1 - 1e-37 128.5 1.0 1e-37 128.5 1.0 2.5 2 1 1 3 3 3 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KKK16325.1 - 1.2e-05 25.1 3.4 1.6e-05 24.6 2.1 1.8 2 1 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Inhibitor_I66 PF16850.5 KKK16325.1 - 0.16 11.9 0.0 4.5 7.1 0.0 2.2 2 0 0 2 2 2 0 Peptidase inhibitor I66 MFS_1 PF07690.16 KKK16326.1 - 3.5e-45 154.5 49.1 3.6e-43 147.8 48.9 3.4 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KKK16326.1 - 1.6e-08 33.8 12.8 1.6e-08 33.8 12.8 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter DUF1430 PF07242.11 KKK16326.1 - 1.2 9.4 0.0 1.2 9.4 0.0 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF1430) Abhydrolase_1 PF00561.20 KKK16327.1 - 1.4e-09 37.9 0.0 2.9e-09 36.9 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KKK16327.1 - 9.7e-06 25.0 0.0 1.7e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KKK16327.1 - 0.00013 22.6 1.9 0.00013 22.6 1.9 2.8 1 1 1 3 3 3 1 Alpha/beta hydrolase family Ndr PF03096.14 KKK16327.1 - 0.0057 15.4 0.0 0.0078 15.0 0.0 1.2 1 0 0 1 1 1 1 Ndr family EthD PF07110.11 KKK16327.1 - 0.029 15.5 0.2 5.8 8.1 0.0 2.7 2 0 0 2 2 2 0 EthD domain Glyoxalase PF00903.25 KKK16328.1 - 6.6e-33 113.6 0.0 1e-15 58.1 0.0 2.8 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Fungal_trans PF04082.18 KKK16328.1 - 7.1e-17 61.3 0.0 1.4e-16 60.4 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyoxalase_4 PF13669.6 KKK16328.1 - 1.9e-12 47.4 0.0 9.7e-05 22.6 0.0 3.1 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 KKK16328.1 - 0.0012 19.0 0.0 2.7 8.1 0.0 3.7 3 1 0 4 4 4 1 Glyoxalase-like domain Glyoxalase_6 PF18029.1 KKK16328.1 - 0.0052 17.6 0.0 0.38 11.5 0.0 3.2 3 0 0 3 3 3 1 Glyoxalase-like domain Glyoxalase_2 PF12681.7 KKK16328.1 - 0.25 11.3 1.2 3.2 7.7 0.0 3.3 3 1 0 3 3 3 0 Glyoxalase-like domain SR-25 PF10500.9 KKK16328.1 - 0.67 9.5 7.5 1.1 8.8 7.5 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Pkinase PF00069.25 KKK16330.1 - 7.8e-71 238.5 0.0 1.1e-70 238.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK16330.1 - 2.5e-30 105.6 0.0 3.3e-30 105.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KKK16330.1 - 0.00048 19.2 0.1 0.016 14.2 0.0 2.1 2 0 0 2 2 2 1 Haspin like kinase domain Kinase-like PF14531.6 KKK16330.1 - 0.0013 18.1 0.0 0.0023 17.3 0.0 1.4 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 KKK16330.1 - 0.0026 17.7 0.6 0.0051 16.8 0.1 1.7 2 1 0 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KKK16330.1 - 0.017 14.2 0.0 0.026 13.6 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Peptidase_C2 PF00648.21 KKK16331.1 - 3e-50 171.0 4.9 2.4e-48 164.7 4.9 3.3 1 1 0 1 1 1 1 Calpain family cysteine protease Abhydrolase_6 PF12697.7 KKK16334.1 - 6.4e-06 26.9 2.5 7.5e-05 23.4 2.5 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KKK16334.1 - 0.047 12.9 0.0 0.21 10.8 0.0 1.9 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 KKK16334.1 - 0.06 13.2 0.1 0.2 11.5 0.0 2.0 2 0 0 2 2 2 0 alpha/beta hydrolase fold JAB PF01398.21 KKK16335.1 - 2.3e-08 34.0 1.3 6.9e-07 29.3 0.5 2.6 2 1 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease CK_II_beta PF01214.18 KKK16336.1 - 3.6e-75 251.8 0.1 4.9e-75 251.3 0.1 1.2 1 0 0 1 1 1 1 Casein kinase II regulatory subunit CxC5 PF18718.1 KKK16336.1 - 0.064 13.3 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 CxC5 like cysteine cluster associated with KDZ transposases Uso1_p115_C PF04871.13 KKK16336.1 - 0.9 9.9 5.6 1.7 9.0 5.6 1.4 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region AdoHcyase PF05221.17 KKK16337.1 - 2.1e-129 430.9 0.0 3.1e-74 249.8 0.2 2.0 1 1 1 2 2 2 2 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 KKK16337.1 - 2.5e-83 278.0 1.3 3.8e-83 277.4 1.3 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 KKK16337.1 - 9.2e-06 25.1 0.1 1.9e-05 24.1 0.1 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 KKK16337.1 - 0.00037 20.1 0.2 0.00068 19.2 0.2 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain TrkA_N PF02254.18 KKK16337.1 - 0.0018 18.5 0.1 0.0038 17.5 0.1 1.5 1 0 0 1 1 1 1 TrkA-N domain Oxidored_nitro PF00148.19 KKK16337.1 - 0.032 13.0 0.1 0.35 9.6 0.0 2.1 2 0 0 2 2 2 0 Nitrogenase component 1 type Oxidoreductase ELFV_dehydrog PF00208.21 KKK16337.1 - 0.054 13.2 0.1 0.1 12.3 0.1 1.5 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase DUF2464 PF10240.9 KKK16338.1 - 0.79 9.2 3.1 0.79 9.2 2.4 1.3 1 1 0 1 1 1 0 Multivesicular body subunit 12 Peptidase_S15 PF02129.18 KKK16338.1 - 0.82 9.2 10.1 0.88 9.1 9.5 1.3 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) DUF4661 PF15576.6 KKK16338.1 - 1.3 8.9 9.4 1.6 8.6 9.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) WLM PF08325.10 KKK16338.1 - 2.4 8.2 9.1 1.5 8.9 6.9 1.8 1 1 0 1 1 1 0 WLM domain DEAD PF00270.29 KKK16339.1 - 1.9e-50 171.0 0.0 1e-49 168.7 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KKK16339.1 - 4.5e-27 94.6 0.0 1.9e-26 92.6 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KKK16339.1 - 0.0039 17.2 0.0 0.017 15.1 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit adh_short PF00106.25 KKK16340.1 - 4.8e-32 111.0 0.0 1.5e-15 57.2 0.0 2.4 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KKK16340.1 - 3.3e-28 98.8 0.3 1.1e-16 61.1 0.0 2.8 2 1 1 3 3 3 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KKK16340.1 - 1.2e-11 44.9 0.1 9.2e-07 28.9 0.0 2.6 1 1 1 2 2 2 2 KR domain SUIM_assoc PF16619.5 KKK16340.1 - 0.0011 19.0 0.5 0.0019 18.2 0.5 1.5 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 Epimerase PF01370.21 KKK16340.1 - 0.024 14.1 0.0 0.6 9.5 0.0 2.3 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family zf-C2H2 PF00096.26 KKK16341.1 - 8e-19 67.0 51.2 7.8e-07 29.2 1.8 7.8 7 0 0 7 7 7 6 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KKK16341.1 - 6.4e-15 54.8 49.4 1.1e-08 35.1 0.9 8.3 8 0 0 8 8 8 4 Zinc-finger double domain zf-met PF12874.7 KKK16341.1 - 2.2e-12 46.9 12.8 0.0022 18.3 0.2 5.5 4 0 0 4 4 4 4 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KKK16341.1 - 4.9e-10 39.2 20.3 0.0012 18.8 0.5 5.3 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_4 PF13894.6 KKK16341.1 - 1.8e-09 37.6 58.6 0.00024 21.7 1.2 9.1 9 0 0 9 9 9 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KKK16341.1 - 1.8e-08 34.4 12.1 0.028 14.7 0.1 5.5 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 KKK16341.1 - 5.3e-05 22.9 15.3 0.18 11.6 0.2 5.4 4 1 0 4 4 4 3 zinc-finger C2H2-type FOXP-CC PF16159.5 KKK16341.1 - 0.0065 17.1 0.8 0.0065 17.1 0.8 5.2 3 1 2 5 5 5 1 FOXP coiled-coil domain zf-H2C2_5 PF13909.6 KKK16341.1 - 0.53 10.1 27.6 0.32 10.8 0.9 6.1 6 0 0 6 6 6 0 C2H2-type zinc-finger domain HMG_box PF00505.19 KKK16342.1 - 2.1e-10 40.9 2.1 2.1e-10 40.9 2.1 3.3 3 1 0 3 3 3 2 HMG (high mobility group) box HMG_box_2 PF09011.10 KKK16342.1 - 2.2e-09 37.8 13.6 3.4e-07 30.7 0.6 3.0 3 0 0 3 3 3 2 HMG-box domain DUF4790 PF16037.5 KKK16342.1 - 0.25 11.8 2.2 0.63 10.5 0.2 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4790) ALMT PF11744.8 KKK16342.1 - 8.9 5.0 7.2 12 4.6 7.2 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Trypan_PARP PF05887.11 KKK16343.1 - 0.00042 20.3 37.4 0.00042 20.3 37.4 15.9 8 3 9 18 18 18 5 Procyclic acidic repetitive protein (PARP) DUF737 PF05300.11 KKK16343.1 - 0.0066 16.8 13.1 0.0066 16.8 13.1 8.3 4 1 0 4 4 4 1 Protein of unknown function (DUF737) CRAL_TRIO PF00650.20 KKK16344.1 - 5e-13 49.1 0.2 1.2e-12 47.9 0.2 1.6 1 1 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 KKK16344.1 - 0.024 14.8 0.0 0.029 14.5 0.0 1.1 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain SAM_decarbox PF01536.16 KKK16345.1 - 3.4e-130 434.2 0.0 4.2e-130 433.9 0.0 1.1 1 0 0 1 1 1 1 Adenosylmethionine decarboxylase TAF6_C PF07571.13 KKK16345.1 - 4.3e-32 110.3 0.0 9.9e-32 109.1 0.0 1.7 1 0 0 1 1 1 1 TAF6 C-terminal HEAT repeat domain TAF PF02969.17 KKK16345.1 - 7e-24 83.8 0.1 1.8e-23 82.4 0.1 1.8 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Histone PF00125.24 KKK16345.1 - 0.0024 18.2 0.3 0.0068 16.8 0.3 1.8 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KKK16345.1 - 0.015 15.6 0.0 0.04 14.2 0.0 1.7 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 KKK16345.1 - 0.11 12.6 0.3 0.27 11.3 0.3 1.5 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit VanZ PF04892.12 KKK16351.1 - 4.5e-07 30.6 0.7 9.2e-07 29.6 0.7 1.5 1 1 0 1 1 1 1 VanZ like family Virul_fac_BrkB PF03631.15 KKK16351.1 - 0.11 12.1 0.3 0.15 11.7 0.3 1.2 1 0 0 1 1 1 0 Virulence factor BrkB Bromodomain PF00439.25 KKK16352.1 - 1.1e-17 63.9 0.2 1.1e-17 63.9 0.2 2.4 3 0 0 3 3 3 1 Bromodomain Bromo_TP PF07524.13 KKK16352.1 - 5.3e-09 36.0 0.0 2.4e-08 33.9 0.0 2.1 2 0 0 2 2 2 1 Bromodomain associated PBP1_TM PF14812.6 KKK16352.1 - 0.0092 16.3 5.7 0.0092 16.3 5.7 2.5 2 0 0 2 2 2 1 Transmembrane domain of transglycosylase PBP1 at N-terminal HisKA_3 PF07730.13 KKK16352.1 - 0.017 15.6 0.8 0.24 11.9 0.0 3.0 2 0 0 2 2 2 0 Histidine kinase Talin_middle PF09141.10 KKK16352.1 - 0.045 13.8 0.5 0.34 10.9 0.3 2.4 2 0 0 2 2 2 0 Talin, middle domain CENP-B_dimeris PF09026.10 KKK16352.1 - 0.55 10.7 7.1 2.4 8.6 7.1 2.1 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF4407 PF14362.6 KKK16352.1 - 5.7 6.2 8.2 11 5.3 8.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Piwi PF02171.17 KKK16353.1 - 6.4e-71 239.1 0.0 9.2e-71 238.5 0.0 1.2 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 KKK16353.1 - 3.4e-18 66.6 0.0 8.1e-18 65.4 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL1 PF08699.10 KKK16353.1 - 9.1e-18 63.7 0.5 3e-17 62.0 0.1 2.1 2 0 0 2 2 2 1 Argonaute linker 1 domain ArgoL2 PF16488.5 KKK16353.1 - 6.4e-13 48.8 0.0 1.7e-12 47.5 0.0 1.8 1 0 0 1 1 1 1 Argonaute linker 2 domain PAZ PF02170.22 KKK16353.1 - 1.6e-12 47.4 0.0 3e-12 46.5 0.0 1.3 1 0 0 1 1 1 1 PAZ domain ArgoMid PF16487.5 KKK16353.1 - 1e-09 38.5 0.0 2.6e-09 37.2 0.0 1.7 1 0 0 1 1 1 1 Mid domain of argonaute OmdA PF13376.6 KKK16354.1 - 1.8e-14 53.5 0.2 3.3e-14 52.6 0.2 1.5 1 0 0 1 1 1 1 Bacteriocin-protection, YdeI or OmpD-Associated Unstab_antitox PF09720.10 KKK16354.1 - 0.031 14.3 0.1 0.28 11.3 0.0 2.2 2 0 0 2 2 2 0 Putative addiction module component Isochorismatase PF00857.20 KKK16355.1 - 9.3e-17 61.8 0.0 1.9e-16 60.7 0.0 1.5 1 1 0 1 1 1 1 Isochorismatase family Fungal_trans_2 PF11951.8 KKK16356.1 - 0.028 13.2 0.0 0.035 12.9 0.0 1.2 1 0 0 1 1 1 0 Fungal specific transcription factor domain CPSase_L_D2 PF02786.17 KKK16357.1 - 4.8e-114 379.1 0.2 5.2e-84 281.0 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.22 KKK16357.1 - 7.7e-48 161.6 0.0 1.9e-47 160.3 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain OTCace_N PF02729.21 KKK16357.1 - 6.3e-46 156.1 0.0 1.3e-45 155.1 0.0 1.6 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain GATase PF00117.28 KKK16357.1 - 1.7e-45 155.2 0.0 1.2e-44 152.4 0.0 2.2 2 0 0 2 2 2 1 Glutamine amidotransferase class-I CPSase_L_D3 PF02787.19 KKK16357.1 - 5.1e-38 130.2 0.0 1.2e-37 128.9 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain OTCace PF00185.24 KKK16357.1 - 2.2e-32 112.3 0.0 4.9e-32 111.2 0.0 1.6 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain MGS PF02142.22 KKK16357.1 - 2.9e-21 75.4 0.0 1.6e-20 73.1 0.0 2.4 2 0 0 2 2 2 1 MGS-like domain Dala_Dala_lig_C PF07478.13 KKK16357.1 - 1.8e-18 66.8 0.5 3.2e-08 33.3 0.1 2.4 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 KKK16357.1 - 3.8e-16 59.1 0.1 1.1e-07 31.6 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.6 KKK16357.1 - 4.1e-10 39.5 0.1 0.00012 21.9 0.0 2.9 3 0 0 3 3 3 2 ATP-grasp in the biosynthetic pathway with Ter operon Peptidase_C26 PF07722.13 KKK16357.1 - 7e-06 26.0 0.2 0.00055 19.7 0.2 2.7 1 1 0 1 1 1 1 Peptidase C26 ATP-grasp_3 PF02655.14 KKK16357.1 - 2.5e-05 24.4 0.7 0.2 11.7 0.1 2.9 3 0 0 3 3 3 2 ATP-grasp domain DJ-1_PfpI PF01965.24 KKK16357.1 - 7e-05 22.7 0.7 0.28 11.0 0.0 4.8 5 0 0 5 5 5 1 DJ-1/PfpI family GARS_A PF01071.19 KKK16357.1 - 0.001 18.9 0.3 0.41 10.4 0.0 2.8 3 0 0 3 3 3 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Peptidase_C25_C PF03785.14 KKK16357.1 - 0.039 13.8 0.6 0.75 9.7 0.2 3.1 2 0 0 2 2 2 0 Peptidase family C25, C terminal ig-like domain TrkA_N PF02254.18 KKK16357.1 - 0.17 12.2 0.1 1.5 9.1 0.0 2.6 2 0 0 2 2 2 0 TrkA-N domain Abhydrolase_3 PF07859.13 KKK16358.1 - 6.5e-39 134.0 0.0 8.3e-39 133.6 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KKK16358.1 - 7.4e-06 25.6 0.0 0.0021 17.6 0.0 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family COesterase PF00135.28 KKK16358.1 - 0.00022 20.3 0.0 0.00083 18.3 0.0 1.7 1 1 0 1 1 1 1 Carboxylesterase family DLH PF01738.18 KKK16358.1 - 0.011 15.3 0.0 0.22 11.0 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family Peptidase_S15 PF02129.18 KKK16358.1 - 0.018 14.6 0.0 1.3 8.6 0.0 2.3 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) AXE1 PF05448.12 KKK16358.1 - 0.021 13.5 0.1 1.3 7.6 0.0 2.4 3 0 0 3 3 3 0 Acetyl xylan esterase (AXE1) AMP-binding PF00501.28 KKK16359.1 - 7.9e-75 252.0 0.0 9.4e-75 251.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KKK16359.1 - 6.7e-14 52.6 3.1 7.6e-14 52.5 1.3 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ABC_tran PF00005.27 KKK16360.1 - 1.8e-24 86.8 0.0 1.4e-12 48.3 0.0 3.1 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KKK16360.1 - 1.5e-11 44.7 1.8 0.0017 18.2 0.1 3.3 3 0 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 KKK16360.1 - 2.5e-05 24.4 0.0 0.14 12.4 0.0 2.7 2 0 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 KKK16360.1 - 0.013 15.2 0.0 0.031 14.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 KKK16360.1 - 0.028 14.9 0.4 0.056 13.9 0.4 1.5 1 0 0 1 1 1 0 AAA domain Ploopntkinase1 PF18748.1 KKK16360.1 - 0.028 13.9 0.0 0.089 12.3 0.0 1.7 2 0 0 2 2 2 0 P-loop Nucleotide Kinase1 NB-ARC PF00931.22 KKK16360.1 - 0.031 13.5 0.0 2.7 7.1 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain AAA_28 PF13521.6 KKK16360.1 - 0.059 13.6 0.1 0.2 11.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 KKK16360.1 - 0.12 12.8 0.1 1 9.7 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain NACHT PF05729.12 KKK16360.1 - 0.16 11.9 0.0 0.4 10.6 0.0 1.7 1 0 0 1 1 1 0 NACHT domain DUF3584 PF12128.8 KKK16360.1 - 0.17 9.4 0.2 0.24 8.9 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) SR-25 PF10500.9 KKK16360.1 - 0.32 10.6 18.3 0.65 9.6 18.3 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Synaptobrevin PF00957.21 KKK16363.1 - 1.5e-31 108.0 0.0 2.1e-31 107.6 0.0 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 KKK16363.1 - 5.4e-28 96.9 0.1 8.4e-28 96.2 0.1 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain zf-C2H2_aberr PF17017.5 KKK16364.1 - 0.031 14.4 0.6 0.048 13.8 0.6 1.2 1 0 0 1 1 1 0 Aberrant zinc-finger FOXP-CC PF16159.5 KKK16364.1 - 0.45 11.2 3.9 4 8.1 0.4 2.7 1 1 1 2 2 2 0 FOXP coiled-coil domain Ost4 PF10215.9 KKK16365.1 - 8.9e-19 67.0 0.6 1.2e-18 66.6 0.6 1.2 1 0 0 1 1 1 1 Oligosaccaryltransferase Zn_clus PF00172.18 KKK16366.1 - 1.1e-09 38.3 4.0 1.9e-09 37.5 4.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KKK16366.1 - 9.1e-09 34.7 0.0 1.7e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain RabGAP-TBC PF00566.18 KKK16367.1 - 8.4e-42 143.3 0.0 7.7e-40 136.8 0.0 2.9 3 0 0 3 3 3 1 Rab-GTPase-TBC domain CNDH2_C PF16858.5 KKK16367.1 - 0.23 11.3 1.7 0.35 10.7 0.3 1.9 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term RNA_pol_3_Rpc31 PF11705.8 KKK16367.1 - 0.31 11.3 8.5 0.27 11.5 5.5 2.2 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 CENP-B_dimeris PF09026.10 KKK16367.1 - 0.74 10.2 17.0 2.2 8.7 17.0 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain LRS4 PF10422.9 KKK16367.1 - 0.76 9.3 9.7 0.58 9.7 1.6 2.9 2 0 0 2 2 2 0 Monopolin complex subunit LRS4 NOA36 PF06524.12 KKK16367.1 - 0.81 9.0 12.0 2 7.7 12.0 1.6 1 0 0 1 1 1 0 NOA36 protein RXT2_N PF08595.11 KKK16367.1 - 0.98 9.4 5.7 3.6 7.6 5.7 2.0 1 0 0 1 1 1 0 RXT2-like, N-terminal GEN1_C PF18380.1 KKK16367.1 - 1.5 9.8 4.3 1e+02 3.9 0.0 3.0 2 0 0 2 2 2 0 Holliday junction resolvase Gen1 C-terminal domain PBP1_TM PF14812.6 KKK16367.1 - 1.6 9.1 13.6 1.6 9.2 10.3 2.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DNA_pol_phi PF04931.13 KKK16367.1 - 3 5.8 11.3 4.7 5.2 11.3 1.2 1 0 0 1 1 1 0 DNA polymerase phi adh_short_C2 PF13561.6 KKK16368.1 - 6.4e-48 163.3 3.3 4.5e-31 108.2 1.1 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KKK16368.1 - 3e-40 137.8 2.5 5.2e-21 75.0 0.0 2.1 1 1 1 2 2 2 2 short chain dehydrogenase KR PF08659.10 KKK16368.1 - 1.6e-10 41.2 0.3 3.6e-07 30.3 0.0 2.2 2 0 0 2 2 2 2 KR domain Acetyltransf_1 PF00583.25 KKK16369.1 - 0.0034 17.6 0.0 0.0079 16.4 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KKK16369.1 - 0.051 13.5 0.0 0.12 12.3 0.0 1.6 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KKK16369.1 - 0.12 12.8 0.0 13 6.3 0.0 2.2 1 1 0 2 2 2 0 Acetyltransferase (GNAT) domain ABC2_membrane PF01061.24 KKK16370.1 - 2.6e-82 275.3 61.1 5.4e-45 153.4 24.0 3.4 4 0 0 4 4 4 2 ABC-2 type transporter PDR_CDR PF06422.12 KKK16370.1 - 1.6e-37 127.3 6.7 6.4e-31 106.1 0.0 3.4 3 0 0 3 3 3 2 CDR ABC transporter ABC_tran PF00005.27 KKK16370.1 - 9e-36 123.4 0.0 1.8e-16 60.9 0.0 3.6 4 0 0 4 4 4 2 ABC transporter ABC_trans_N PF14510.6 KKK16370.1 - 7.1e-20 71.4 0.1 1.7e-19 70.2 0.1 1.6 1 0 0 1 1 1 1 ABC-transporter N-terminal RsgA_GTPase PF03193.16 KKK16370.1 - 0.00026 20.9 0.0 0.013 15.4 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 KKK16370.1 - 0.00035 21.0 0.0 0.19 12.1 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.6 KKK16370.1 - 0.00061 19.4 0.1 0.0017 17.9 0.0 1.7 2 0 0 2 2 2 1 AAA domain ABC2_membrane_3 PF12698.7 KKK16370.1 - 0.00094 18.4 41.1 0.0011 18.1 18.2 3.0 2 1 0 2 2 2 1 ABC-2 family transporter protein SMC_N PF02463.19 KKK16370.1 - 0.0084 15.6 0.0 0.66 9.4 0.0 2.8 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KKK16370.1 - 0.013 15.3 0.1 0.86 9.4 0.1 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_33 PF13671.6 KKK16370.1 - 0.021 15.0 0.0 2 8.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KKK16370.1 - 0.022 15.3 0.0 0.22 12.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.6 KKK16370.1 - 0.022 14.6 0.1 4.4 7.0 0.1 2.6 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system NACHT PF05729.12 KKK16370.1 - 0.14 12.1 3.1 14 5.6 0.1 3.3 3 0 0 3 3 3 0 NACHT domain AAA_30 PF13604.6 KKK16370.1 - 0.16 11.7 0.2 7.3 6.2 0.1 2.4 2 0 0 2 2 2 0 AAA domain zf-Sec23_Sec24 PF04810.15 KKK16370.1 - 0.17 11.9 0.1 0.67 10.1 0.0 2.1 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger AAA_22 PF13401.6 KKK16370.1 - 0.28 11.4 0.7 11 6.2 0.1 2.6 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 KKK16370.1 - 0.28 10.7 1.1 1.3 8.6 0.1 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MMM1 PF10296.9 KKK16393.1 - 6.8e-06 25.4 0.0 1.4e-05 24.3 0.0 1.5 1 1 0 1 1 1 1 Maintenance of mitochondrial morphology protein 1 NAD_binding_8 PF13450.6 KKK16402.1 - 5e-08 33.1 0.0 1e-07 32.1 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 KKK16402.1 - 3.9e-05 23.1 0.0 5.9e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.14 KKK16402.1 - 0.00072 18.9 0.0 0.014 14.7 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KKK16402.1 - 0.011 15.1 0.0 0.015 14.7 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KKK16402.1 - 0.022 14.0 0.0 0.034 13.4 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain DAO PF01266.24 KKK16402.1 - 0.022 14.4 0.0 0.042 13.4 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KKK16402.1 - 0.038 13.2 0.1 0.059 12.6 0.1 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KKK16402.1 - 0.047 12.9 0.0 0.083 12.1 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.12 KKK16402.1 - 0.12 11.4 0.1 0.22 10.5 0.1 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_binding_9 PF13454.6 KKK16402.1 - 0.15 12.1 0.2 1.3 9.0 0.0 2.4 3 0 0 3 3 3 0 FAD-NAD(P)-binding HI0933_like PF03486.14 KKK16402.1 - 0.16 10.6 0.0 0.23 10.1 0.0 1.1 1 0 0 1 1 1 0 HI0933-like protein Med5 PF08689.10 KKK16403.1 - 1.2e-174 583.0 0.0 3e-174 581.7 0.0 1.6 1 1 0 1 1 1 1 Mediator complex subunit Med5 zf-CCCH PF00642.24 KKK16403.1 - 0.14 12.1 0.1 0.29 11.1 0.1 1.4 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Iso_dh PF00180.20 KKK16413.1 - 1.2e-116 389.7 0.0 1.4e-116 389.4 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase CDP-OH_P_transf PF01066.21 KKK16414.1 - 5e-13 49.6 0.8 5e-13 49.6 0.8 2.3 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase PP2C PF00481.21 KKK16415.1 - 3.3e-33 115.4 0.0 6.9e-28 98.0 0.0 2.3 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 KKK16415.1 - 3.7e-05 23.5 0.0 0.00011 21.9 0.0 1.8 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 KKK16415.1 - 0.033 14.1 0.0 0.056 13.3 0.0 1.3 1 0 0 1 1 1 0 Stage II sporulation protein E (SpoIIE) CNH PF00780.22 KKK16416.1 - 1.2e-81 274.3 0.0 8.9e-81 271.5 0.0 2.0 2 0 0 2 2 2 1 CNH domain PH_5 PF15405.6 KKK16416.1 - 2.3e-41 141.1 0.0 7.1e-41 139.5 0.0 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.20 KKK16416.1 - 9.6e-38 130.2 0.0 1.9e-37 129.3 0.0 1.5 1 0 0 1 1 1 1 RhoGEF domain DEP PF00610.21 KKK16416.1 - 1.4e-14 53.9 0.0 3.2e-14 52.7 0.0 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Pkinase PF00069.25 KKK16447.1 - 8.2e-73 245.0 0.0 1.2e-72 244.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK16447.1 - 1e-37 129.8 0.0 2.8e-37 128.4 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KKK16447.1 - 0.00097 18.5 0.8 2.3 7.5 0.0 3.0 3 0 0 3 3 3 2 Kinase-like Pkinase_fungal PF17667.1 KKK16447.1 - 0.11 11.3 0.0 0.27 10.0 0.0 1.7 2 0 0 2 2 2 0 Fungal protein kinase Methyltransf_25 PF13649.6 KKK16448.1 - 1.1e-07 32.5 0.0 2e-07 31.6 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KKK16448.1 - 1.5e-06 28.2 0.0 1.8e-06 27.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KKK16448.1 - 2.6e-05 24.8 0.0 4.1e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KKK16448.1 - 0.00065 20.4 0.0 0.001 19.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KKK16448.1 - 0.0016 18.3 0.0 0.0023 17.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.20 KKK16448.1 - 0.004 16.2 0.0 0.0045 16.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase DREV PF05219.12 KKK16448.1 - 0.0068 15.5 0.0 0.0083 15.2 0.0 1.1 1 0 0 1 1 1 1 DREV methyltransferase NodS PF05401.11 KKK16448.1 - 0.0075 15.9 0.0 0.0098 15.5 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_16 PF10294.9 KKK16448.1 - 0.011 15.5 0.0 0.012 15.3 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase MTS PF05175.14 KKK16448.1 - 0.044 13.3 0.0 0.057 13.0 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain PCMT PF01135.19 KKK16448.1 - 0.051 13.3 0.1 0.067 12.9 0.1 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.13 KKK16448.1 - 0.11 11.9 0.1 0.12 11.8 0.1 1.2 1 1 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.6 KKK16448.1 - 0.17 11.8 0.0 0.21 11.6 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.18 KKK16448.1 - 0.18 11.1 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family AMP-binding PF00501.28 KKK16449.1 - 5.4e-29 101.0 0.0 8.6e-29 100.4 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 KKK16449.1 - 8.3e-27 94.0 0.0 1.3e-26 93.3 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 KKK16449.1 - 6.1e-13 48.8 0.0 9.8e-13 48.1 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 KKK16449.1 - 6.5e-05 23.2 0.0 0.0002 21.7 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site KR PF08659.10 KKK16449.1 - 0.011 15.7 0.0 0.069 13.0 0.1 2.3 2 1 0 2 2 2 0 KR domain GDP_Man_Dehyd PF16363.5 KKK16449.1 - 0.023 14.1 0.0 0.054 12.9 0.0 1.6 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase Glu_dehyd_C PF16912.5 KKK16449.1 - 0.031 13.7 0.0 0.056 12.9 0.0 1.4 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus DXP_reductoisom PF02670.16 KKK16449.1 - 0.13 12.9 0.0 0.3 11.8 0.0 1.6 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Glyco_hydro_16 PF00722.21 KKK16450.1 - 8.5e-08 31.9 0.2 7.5e-07 28.8 0.0 2.6 1 1 1 2 2 2 1 Glycosyl hydrolases family 16 Methyltransf_2 PF00891.18 KKK16452.1 - 3.6e-17 62.4 0.0 6.3e-17 61.6 0.0 1.5 1 1 0 1 1 1 1 O-methyltransferase domain Dimerisation PF08100.11 KKK16452.1 - 0.00095 19.1 0.7 0.0026 17.7 0.7 1.8 1 0 0 1 1 1 1 Dimerisation domain Dimerisation2 PF16864.5 KKK16452.1 - 0.002 18.0 0.0 0.0042 17.0 0.0 1.5 1 0 0 1 1 1 1 Dimerisation domain PAS_9 PF13426.7 KKK16453.1 - 4.4e-27 94.4 0.0 4.1e-18 65.6 0.0 3.4 3 0 0 3 3 3 3 PAS domain PAS_3 PF08447.12 KKK16453.1 - 2.4e-20 72.6 0.0 1.1e-09 38.5 0.0 3.7 3 0 0 3 3 3 3 PAS fold PAS PF00989.25 KKK16453.1 - 5.5e-14 52.1 0.0 0.00013 22.0 0.0 3.6 3 0 0 3 3 3 3 PAS fold GATA PF00320.27 KKK16453.1 - 6.4e-14 51.3 5.6 6.4e-14 51.3 5.6 1.9 2 0 0 2 2 2 1 GATA zinc finger PAS_4 PF08448.10 KKK16453.1 - 1.8e-10 41.0 0.0 0.056 13.7 0.0 3.6 3 0 0 3 3 3 3 PAS fold PAS_11 PF14598.6 KKK16453.1 - 2e-08 34.4 0.0 4.1e-05 23.7 0.0 2.8 3 0 0 3 3 3 2 PAS domain PAS_8 PF13188.7 KKK16453.1 - 0.0032 17.4 0.0 0.02 14.9 0.0 2.2 3 0 0 3 3 3 1 PAS domain PAS_2 PF08446.11 KKK16453.1 - 0.012 16.3 0.0 0.46 11.2 0.0 2.6 2 0 0 2 2 2 0 PAS fold Telomerase_RBD PF12009.8 KKK16462.1 - 3.5e-46 156.6 0.0 9.7e-46 155.2 0.1 1.8 2 0 0 2 2 2 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.27 KKK16462.1 - 2.5e-12 46.8 0.0 5.1e-08 32.7 0.0 2.3 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RabGAP-TBC PF00566.18 KKK16463.1 - 7.8e-27 94.3 0.0 1.2e-26 93.7 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain SBE2 PF17076.5 KKK16463.1 - 3.5e-07 28.9 1.2 3.5e-07 28.9 1.2 2.1 2 0 0 2 2 2 2 SBE2, cell-wall formation Synaphin PF05835.12 KKK16463.1 - 0.088 13.1 3.5 0.2 12.0 3.5 1.5 1 0 0 1 1 1 0 Synaphin protein Metal_resist PF13801.6 KKK16463.1 - 0.59 10.3 3.8 14 5.9 2.1 3.2 2 0 0 2 2 2 0 Heavy-metal resistance AA_permease_2 PF13520.6 KKK16465.1 - 6.9e-69 232.7 47.1 8.2e-69 232.5 47.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KKK16465.1 - 9.4e-19 67.3 37.6 1.3e-18 66.9 37.6 1.2 1 0 0 1 1 1 1 Amino acid permease DUF2304 PF10066.9 KKK16465.1 - 6 7.1 16.7 0.19 11.9 0.5 3.2 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2304) Bestrophin PF01062.21 KKK16466.1 - 5.8e-10 39.0 0.1 8.1e-10 38.6 0.1 1.2 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel SSP160 PF06933.11 KKK16466.1 - 0.07 11.3 0.0 0.085 11.1 0.0 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 WD40 PF00400.32 KKK16467.1 - 3.4e-16 59.3 8.3 5.3e-07 30.2 0.1 4.5 4 0 0 4 4 4 2 WD domain, G-beta repeat CAF1C_H4-bd PF12265.8 KKK16467.1 - 1.9e-15 56.9 0.0 1.8e-14 53.7 0.0 2.5 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex ANAPC4_WD40 PF12894.7 KKK16467.1 - 8.6e-09 35.6 1.5 0.00032 21.0 0.2 3.1 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain UL41A PF17591.2 KKK16467.1 - 0.19 11.8 0.0 0.53 10.4 0.0 1.7 1 0 0 1 1 1 0 Herpesvirus UL41A DUF1749 PF08538.10 KKK16468.1 - 2.7e-95 318.9 0.0 3.3e-95 318.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.7 KKK16468.1 - 4e-05 24.3 0.1 6.5e-05 23.6 0.1 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KKK16468.1 - 0.00049 19.8 0.1 0.0016 18.1 0.1 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold PGAP1 PF07819.13 KKK16468.1 - 0.0058 16.4 0.0 0.017 14.8 0.0 1.7 2 0 0 2 2 2 1 PGAP1-like protein Hydrolase_4 PF12146.8 KKK16468.1 - 0.053 12.8 0.0 0.14 11.4 0.0 1.8 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Acetyltransf_8 PF13523.6 KKK16469.1 - 4.4e-38 130.2 0.0 6.6e-38 129.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain F-box-like PF12937.7 KKK16470.1 - 4.6e-08 32.8 3.3 1.4e-05 24.9 0.1 3.0 3 0 0 3 3 3 2 F-box-like F-box PF00646.33 KKK16470.1 - 3.5e-05 23.6 2.1 0.00019 21.2 0.3 2.6 2 0 0 2 2 2 1 F-box domain Metallophos PF00149.28 KKK16471.1 - 1.9e-19 71.0 0.3 3.8e-19 70.0 0.3 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.6 KKK16471.1 - 2.2e-14 54.1 0.2 6.2e-14 52.6 0.2 1.9 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C Pur_ac_phosph_N PF16656.5 KKK16471.1 - 1e-13 51.7 0.1 2.5e-13 50.4 0.1 1.7 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain fn3 PF00041.21 KKK16471.1 - 0.00049 20.4 0.1 0.0017 18.7 0.1 1.8 1 1 0 1 1 1 1 Fibronectin type III domain Peptidase_C14 PF00656.22 KKK16472.1 - 1.7e-48 165.8 0.0 2.6e-48 165.2 0.0 1.2 1 1 0 1 1 1 1 Caspase domain Glyoxalase_6 PF18029.1 KKK16473.1 - 0.00016 22.4 0.0 0.00024 21.9 0.0 1.3 1 1 0 1 1 1 1 Glyoxalase-like domain Pirin PF02678.16 KKK16474.1 - 1.6e-23 82.8 0.6 4.3e-23 81.4 0.6 1.7 1 1 0 1 1 1 1 Pirin Cupin_2 PF07883.11 KKK16474.1 - 7.4e-06 25.6 1.3 0.00015 21.4 0.3 2.8 2 1 0 2 2 2 1 Cupin domain Pirin_C_2 PF17954.1 KKK16474.1 - 0.15 12.2 0.0 0.57 10.4 0.0 2.0 1 1 0 1 1 1 0 Quercetinase C-terminal cupin domain Hydrolase_4 PF12146.8 KKK16475.1 - 2.2e-38 131.9 0.0 2.8e-38 131.5 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KKK16475.1 - 7.1e-08 33.3 0.3 9.1e-08 33.0 0.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KKK16475.1 - 0.0028 17.3 0.6 0.29 10.7 0.6 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF1749 PF08538.10 KKK16475.1 - 0.0078 15.3 0.0 0.012 14.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Ank_2 PF12796.7 KKK16476.1 - 1.3e-61 205.1 0.8 7.5e-18 64.9 0.0 5.2 1 1 2 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KKK16476.1 - 2.8e-54 180.8 0.0 1.6e-09 38.1 0.0 6.8 2 2 5 7 7 7 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 KKK16476.1 - 4.9e-48 160.6 0.0 2.1e-10 40.7 0.0 6.4 2 1 6 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 KKK16476.1 - 3.5e-47 152.9 0.0 0.0008 19.7 0.0 9.5 10 0 0 10 10 10 9 Ankyrin repeat Ank PF00023.30 KKK16476.1 - 1.7e-43 145.2 1.3 1.6e-05 25.1 0.0 9.2 10 0 0 10 10 10 7 Ankyrin repeat VWA_3_C PF18571.1 KKK16476.1 - 7.9e-07 28.9 16.4 0.0049 16.7 0.0 7.1 8 0 0 8 8 8 2 von Willebrand factor type A C-terminal domain F-box-like PF12937.7 KKK16476.1 - 2.6e-05 24.0 0.6 4.7e-05 23.2 0.6 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KKK16476.1 - 0.009 15.9 0.5 0.015 15.1 0.5 1.3 1 0 0 1 1 1 1 F-box domain Nse4-Nse3_bdg PF15412.6 KKK16476.1 - 0.23 11.6 2.7 33 4.7 0.0 4.4 6 0 0 6 6 6 0 Binding domain of Nse4/EID3 to Nse3-MAGE CAP_GLY PF01302.25 KKK16513.1 - 1.1e-25 89.4 0.0 1.7e-25 88.8 0.0 1.3 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.6 KKK16513.1 - 1.2e-16 60.9 0.0 2.2e-16 60.1 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin-like domain ubiquitin PF00240.23 KKK16513.1 - 0.00043 20.0 0.0 0.001 18.8 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin family E1-E2_ATPase PF00122.20 KKK16514.1 - 2.5e-52 177.0 9.6 4.9e-52 176.1 2.5 2.9 3 0 0 3 3 3 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 KKK16514.1 - 5.3e-23 81.7 0.3 1.7e-22 80.1 0.0 1.9 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KKK16514.1 - 1.4e-21 77.8 1.0 2.3e-20 73.8 1.0 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KKK16514.1 - 5.8e-19 68.0 0.0 1.1e-18 67.1 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KKK16514.1 - 2.2e-16 59.3 0.1 6.9e-16 57.7 0.0 1.9 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KKK16514.1 - 8.7e-08 32.2 1.8 6.1e-06 26.2 0.8 2.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KKK16514.1 - 5.9e-06 26.8 0.0 2.9e-05 24.6 0.0 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase 14-3-3 PF00244.20 KKK16515.1 - 1.1e-107 358.6 2.3 1.3e-107 358.3 2.3 1.1 1 0 0 1 1 1 1 14-3-3 protein Orbi_VP5 PF00901.17 KKK16515.1 - 0.02 13.3 1.1 0.032 12.6 1.1 1.3 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 Enolase_C PF00113.22 KKK16516.1 - 5.4e-153 508.5 0.1 7e-153 508.1 0.1 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 KKK16516.1 - 2.3e-56 189.5 0.3 4.6e-56 188.6 0.1 1.6 2 0 0 2 2 2 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 KKK16516.1 - 5.3e-05 22.9 0.0 8.6e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 KKK16516.1 - 0.025 13.7 0.1 0.83 8.8 0.1 2.5 3 0 0 3 3 3 0 Methylaspartate ammonia-lyase C-terminus 3H PF02829.14 KKK16516.1 - 0.073 13.4 0.1 0.43 10.9 0.0 2.2 2 0 0 2 2 2 0 3H domain eIF3_subunit PF08597.10 KKK16517.1 - 4.1e-69 233.2 33.2 4.6e-69 233.0 33.2 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit PNISR PF15996.5 KKK16517.1 - 0.0077 16.5 9.6 0.0077 16.5 9.6 2.2 2 0 0 2 2 2 1 Arginine/serine-rich protein PNISR DUF2967 PF11179.8 KKK16517.1 - 0.14 10.2 8.6 0.22 9.6 8.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) PRP4 PF08799.11 KKK16517.1 - 0.58 9.8 2.5 1.4 8.6 2.5 1.6 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like FAM60A PF15396.6 KKK16517.1 - 9.5 6.2 12.7 5.4 6.9 7.1 2.1 2 0 0 2 2 2 0 Protein Family FAM60A AAA PF00004.29 KKK16518.1 - 6.5e-43 146.3 0.0 1.1e-42 145.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 KKK16518.1 - 3.9e-11 42.7 0.1 3.8e-10 39.6 0.0 2.3 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 KKK16518.1 - 1.8e-10 40.4 0.1 3.5e-10 39.5 0.1 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 KKK16518.1 - 1.1e-07 32.4 0.0 7.7e-05 23.1 0.0 2.9 2 1 1 3 3 3 1 AAA ATPase domain AAA_2 PF07724.14 KKK16518.1 - 2.3e-06 27.8 0.0 7.6e-06 26.1 0.0 1.9 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 KKK16518.1 - 2.8e-06 27.4 0.0 5.6e-05 23.2 0.0 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KKK16518.1 - 2.8e-06 27.1 0.0 6.3e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 KKK16518.1 - 0.00035 21.1 0.1 0.0029 18.2 0.0 2.4 2 1 0 2 2 2 1 AAA domain DUF815 PF05673.13 KKK16518.1 - 0.00043 19.5 0.0 0.00087 18.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 KKK16518.1 - 0.00061 20.1 0.1 0.023 15.0 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_7 PF12775.7 KKK16518.1 - 0.0023 17.5 0.0 0.0046 16.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region TsaE PF02367.17 KKK16518.1 - 0.0028 17.6 0.1 0.0092 16.0 0.0 1.8 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE TIP49 PF06068.13 KKK16518.1 - 0.003 16.8 0.1 0.0071 15.6 0.0 1.6 2 0 0 2 2 2 1 TIP49 P-loop domain Sigma54_activat PF00158.26 KKK16518.1 - 0.0048 16.6 0.0 0.014 15.1 0.0 1.9 1 1 0 1 1 1 1 Sigma-54 interaction domain IstB_IS21 PF01695.17 KKK16518.1 - 0.0052 16.5 0.0 0.01 15.6 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 KKK16518.1 - 0.0067 15.8 0.0 0.013 14.9 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 KKK16518.1 - 0.0072 16.7 0.0 0.014 15.8 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_3 PF07726.11 KKK16518.1 - 0.0097 15.8 0.1 0.032 14.1 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 KKK16518.1 - 0.015 15.3 0.0 0.032 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KKK16518.1 - 0.018 15.2 0.0 0.041 14.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KKK16518.1 - 0.03 14.0 0.0 0.075 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain GAS PF13851.6 KKK16518.1 - 0.032 13.6 0.8 0.063 12.6 0.8 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding AAA_24 PF13479.6 KKK16518.1 - 0.033 13.9 0.0 0.086 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 KKK16518.1 - 0.038 13.3 0.3 0.13 11.6 0.0 2.1 3 0 0 3 3 2 0 KaiC Prot_ATP_OB_N PF17758.1 KKK16518.1 - 0.039 13.6 0.0 0.11 12.2 0.0 1.7 1 0 0 1 1 1 0 Proteasomal ATPase OB N-terminal domain PhoH PF02562.16 KKK16518.1 - 0.046 13.2 0.0 0.083 12.3 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein Zeta_toxin PF06414.12 KKK16518.1 - 0.047 13.0 0.0 0.094 12.0 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_25 PF13481.6 KKK16518.1 - 0.049 13.2 0.1 0.11 12.0 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KKK16518.1 - 0.079 13.2 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 KKK16518.1 - 0.08 12.0 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_11 PF13086.6 KKK16518.1 - 0.087 12.6 0.1 0.27 11.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KKK16518.1 - 0.1 12.5 0.1 0.26 11.2 0.0 1.7 2 0 0 2 2 2 0 NACHT domain Thymidylate_kin PF02223.17 KKK16518.1 - 0.11 12.1 0.0 7.8 6.1 0.0 2.6 3 0 0 3 3 2 0 Thymidylate kinase DUF16 PF01519.16 KKK16518.1 - 0.14 12.7 0.7 0.38 11.3 0.7 1.7 1 0 0 1 1 1 0 Protein of unknown function DUF16 CEP209_CC5 PF16574.5 KKK16518.1 - 0.15 12.2 2.1 0.44 10.7 2.1 1.8 1 1 0 1 1 1 0 Coiled-coil region of centrosome protein CE290 DUF4482 PF14818.6 KKK16518.1 - 0.55 11.1 2.5 0.35 11.7 0.3 1.8 2 0 0 2 2 1 0 Domain of unknown function (DUF4482) UPF0449 PF15136.6 KKK16533.1 - 0.0077 16.7 0.7 0.0077 16.7 0.7 1.9 2 0 0 2 2 2 1 Uncharacterised protein family UPF0449 CCDC106 PF15794.5 KKK16533.1 - 0.023 14.4 0.3 0.023 14.4 0.3 3.0 3 1 1 4 4 4 0 Coiled-coil domain-containing protein 106 Phage_Mu_Gam PF07352.12 KKK16533.1 - 0.028 14.3 0.5 0.043 13.7 0.5 1.2 1 0 0 1 1 1 0 Bacteriophage Mu Gam like protein DUF4337 PF14235.6 KKK16533.1 - 5.4 7.1 5.8 8.5 6.5 5.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) bZIP_2 PF07716.15 KKK16533.1 - 7.3 6.8 15.4 11 6.2 14.2 1.8 1 1 1 2 2 2 0 Basic region leucine zipper Pkinase PF00069.25 KKK16534.1 - 3e-41 141.5 0.2 9.2e-23 80.9 0.3 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KKK16534.1 - 5.9e-14 52.0 0.5 6.8e-10 38.7 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 KKK16534.1 - 0.051 12.3 1.5 0.05 12.4 0.2 1.6 1 1 1 2 2 2 0 Fungal protein kinase RIO1 PF01163.22 KKK16534.1 - 0.076 12.6 0.0 0.24 11.0 0.0 1.9 1 0 0 1 1 1 0 RIO1 family Ribonuclease_3 PF00636.26 KKK16541.1 - 2.2e-13 50.8 0.0 8.8e-13 48.8 0.0 2.1 2 1 0 2 2 2 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 KKK16541.1 - 2.1e-11 44.1 0.0 3.5e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease-III-like dsrm PF00035.26 KKK16541.1 - 0.00018 22.1 0.0 0.00043 20.9 0.0 1.6 1 0 0 1 1 1 1 Double-stranded RNA binding motif ER_lumen_recept PF00810.18 KKK16542.1 - 2.1e-55 187.6 8.7 3.4e-55 186.9 8.7 1.4 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.14 KKK16542.1 - 0.0036 17.0 5.9 1.7 8.5 0.1 3.7 3 0 0 3 3 3 3 PQ loop repeat DUF4385 PF14328.6 KKK16542.1 - 0.21 11.7 0.3 16 5.6 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4385) Peptidase_S9 PF00326.21 KKK16544.1 - 7.8e-06 25.5 0.0 1.6e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.20 KKK16544.1 - 4.2e-05 23.3 0.8 0.00018 21.3 0.8 1.9 1 1 0 1 1 1 1 Putative esterase Abhydrolase_2 PF02230.16 KKK16544.1 - 0.00042 20.2 0.0 0.041 13.7 0.0 2.7 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase Chlorophyllase PF07224.11 KKK16544.1 - 0.0051 15.9 0.1 0.0086 15.1 0.1 1.2 1 0 0 1 1 1 1 Chlorophyllase Esterase_phd PF10503.9 KKK16544.1 - 0.0069 15.9 0.1 0.012 15.1 0.1 1.4 1 0 0 1 1 1 1 Esterase PHB depolymerase Abhydrolase_6 PF12697.7 KKK16544.1 - 0.025 15.2 0.9 0.066 13.8 0.9 1.8 1 0 0 1 1 1 0 Alpha/beta hydrolase family TPT PF03151.16 KKK16545.1 - 2e-61 207.9 14.3 2.5e-61 207.6 14.3 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KKK16545.1 - 2.4e-09 37.5 30.5 2.3e-05 24.6 10.4 2.8 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 KKK16545.1 - 0.0004 19.7 17.1 0.0021 17.3 17.1 1.9 1 1 0 1 1 1 1 UAA transporter family PSII PF00421.19 KKK16545.1 - 0.022 13.4 1.2 0.023 13.4 0.1 1.5 2 0 0 2 2 2 0 Photosystem II protein PUNUT PF16913.5 KKK16545.1 - 5.2 6.2 19.5 40 3.3 19.3 2.1 1 1 0 1 1 1 0 Purine nucleobase transmembrane transport Wzy_C PF04932.15 KKK16545.1 - 5.6 6.6 9.0 11 5.7 0.1 3.2 3 0 0 3 3 3 0 O-Antigen ligase Molybdopterin PF00384.22 KKK16546.1 - 8e-69 232.7 0.0 7e-35 120.8 0.0 2.2 1 1 1 2 2 2 2 Molybdopterin oxidoreductase Fer2_4 PF13510.6 KKK16546.1 - 4.4e-21 74.7 0.2 1.1e-20 73.4 0.2 1.7 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NADH_dhqG_C PF09326.11 KKK16546.1 - 6.2e-19 68.4 0.1 1.6e-18 67.1 0.1 1.8 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit G, C-terminal NADH-G_4Fe-4S_3 PF10588.9 KKK16546.1 - 2.8e-17 62.0 0.2 2.8e-17 62.0 0.2 2.3 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Fer2 PF00111.27 KKK16546.1 - 2.3e-08 33.9 0.6 2.3e-08 33.9 0.6 2.1 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4 PF00037.27 KKK16546.1 - 0.16 11.8 1.1 4.8 7.2 0.3 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain XRCC4 PF06632.12 KKK16547.1 - 9.6e-09 34.5 11.5 5.4e-08 32.1 11.5 2.2 1 1 0 1 1 1 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 LAT PF15234.6 KKK16547.1 - 0.081 12.7 7.1 0.15 11.7 7.1 1.4 1 0 0 1 1 1 0 Linker for activation of T-cells NOA36 PF06524.12 KKK16547.1 - 7.3 5.8 9.1 13 5.0 9.1 1.3 1 0 0 1 1 1 0 NOA36 protein DTHCT PF08070.11 KKK16547.1 - 9.1 7.1 13.3 31 5.4 11.1 2.6 1 1 0 1 1 1 0 DTHCT (NUC029) region DUF5572 PF17733.1 KKK16548.1 - 9.4e-25 86.2 0.8 2e-24 85.2 0.8 1.6 1 0 0 1 1 1 1 Family of unknown function (DUF5572) PUF PF00806.19 KKK16549.1 - 5e-36 120.4 3.6 2.7e-06 26.8 0.0 9.2 9 0 0 9 9 9 8 Pumilio-family RNA binding repeat CPL PF08144.11 KKK16549.1 - 0.095 13.0 0.1 5.3 7.4 0.0 2.6 2 0 0 2 2 2 0 CPL (NUC119) domain Nup84_Nup100 PF04121.13 KKK16550.1 - 7.5e-181 602.9 2.6 1.2e-180 602.2 2.6 1.3 1 0 0 1 1 1 1 Nuclear pore protein 84 / 107 DNA_pol_phi PF04931.13 KKK16550.1 - 4.4 5.3 17.4 7.1 4.6 17.4 1.2 1 0 0 1 1 1 0 DNA polymerase phi MTCP1 PF08991.10 KKK16551.1 - 3.1e-28 97.8 8.3 4e-28 97.4 8.3 1.1 1 0 0 1 1 1 1 Mature-T-Cell Proliferation I type Cmc1 PF08583.10 KKK16551.1 - 0.015 15.3 1.4 0.015 15.3 1.4 1.7 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like Rad60-SLD PF11976.8 KKK16552.1 - 2.6e-21 75.2 0.2 2.9e-21 75.0 0.2 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 KKK16552.1 - 1.1e-11 44.3 0.1 1.2e-11 44.1 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin family APH PF01636.23 KKK16554.1 - 0.019 14.9 0.1 0.029 14.3 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Cation_ATPase_C PF00689.21 KKK16556.1 - 1.2e-45 155.5 9.7 1.2e-45 155.5 9.7 2.8 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 KKK16556.1 - 1.5e-35 122.3 0.6 1.5e-35 122.3 0.6 2.3 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase PF13246.6 KKK16556.1 - 1.2e-22 79.8 0.0 2.6e-22 78.7 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KKK16556.1 - 3.6e-19 69.9 0.0 1e-18 68.4 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KKK16556.1 - 1.6e-08 34.1 0.3 1.2e-07 31.3 0.0 2.5 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KKK16556.1 - 0.0016 18.2 1.3 0.0037 17.0 0.7 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase RskA PF10099.9 KKK16556.1 - 0.0027 18.0 3.5 3.7 7.8 0.0 4.0 3 1 0 3 3 3 2 Anti-sigma-K factor rskA LptF_LptG PF03739.14 KKK16556.1 - 0.013 14.4 4.4 0.033 13.0 4.4 1.7 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG DUF4870 PF09685.10 KKK16556.1 - 0.11 12.6 0.1 0.11 12.6 0.1 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4870) CD34_antigen PF06365.12 KKK16557.1 - 0.085 12.4 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 CD34/Podocalyxin family CYSTM PF12734.7 KKK16558.1 - 7e-05 23.1 39.1 7e-05 23.1 39.1 4.4 1 1 2 3 3 3 1 Cysteine-rich TM module stress tolerance ABC2_membrane PF01061.24 KKK16562.1 - 7.7e-19 67.9 20.9 9.5e-19 67.7 20.9 1.0 1 0 0 1 1 1 1 ABC-2 type transporter Aa_trans PF01490.18 KKK16563.1 - 8.7e-54 182.8 37.1 9.9e-54 182.6 37.1 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Phage_holin_3_7 PF05449.11 KKK16563.1 - 3.8 7.6 6.9 0.25 11.4 0.4 2.5 2 1 0 2 2 2 0 Putative 3TM holin, Phage_holin_3 Myb_DNA-binding PF00249.31 KKK16564.1 - 4.5e-10 39.6 0.0 1.1e-05 25.5 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 KKK16564.1 - 0.0017 18.2 1.2 0.0023 17.8 0.0 1.8 2 0 0 2 2 2 1 Myb DNA-binding like Myb_DNA-bind_6 PF13921.6 KKK16564.1 - 0.064 13.5 0.2 0.66 10.3 0.2 2.3 2 0 0 2 2 2 0 Myb-like DNA-binding domain p450 PF00067.22 KKK16565.1 - 9.1e-62 209.3 0.0 1e-61 209.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Redoxin PF08534.10 KKK16566.1 - 2.7e-37 127.8 0.0 3e-37 127.6 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 KKK16566.1 - 1.2e-10 41.4 0.0 1.5e-10 41.1 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family AhpC-TSA_2 PF13911.6 KKK16566.1 - 0.15 12.2 0.0 0.22 11.7 0.0 1.3 1 0 0 1 1 1 0 AhpC/TSA antioxidant enzyme DUF1524 PF07510.11 KKK16567.1 - 3.6e-10 39.8 0.0 4.4e-10 39.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1524) GH-E PF14410.6 KKK16567.1 - 0.006 17.0 0.0 0.046 14.1 0.0 2.0 2 0 0 2 2 2 1 HNH/ENDO VII superfamily nuclease with conserved GHE residues HNH_4 PF13395.6 KKK16567.1 - 0.088 12.7 0.9 0.41 10.6 0.9 2.0 1 1 0 1 1 1 0 HNH endonuclease Med1 PF10744.9 KKK16589.1 - 4.6e-126 421.2 0.0 5.7e-126 420.9 0.0 1.1 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription subunit 1 SRAP PF02586.14 KKK16591.1 - 3.4e-79 265.4 0.0 5.1e-79 264.8 0.0 1.3 1 0 0 1 1 1 1 SOS response associated peptidase (SRAP) TPR_2 PF07719.17 KKK16592.1 - 1e-05 25.2 5.2 0.0013 18.7 0.1 4.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 KKK16592.1 - 1.1e-05 25.7 0.7 0.027 14.8 0.0 4.5 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 KKK16592.1 - 0.00015 21.4 8.3 0.0014 18.4 0.1 3.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_10 PF13374.6 KKK16592.1 - 0.013 15.3 0.0 0.013 15.3 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 KKK16592.1 - 0.25 11.5 2.5 1.1 9.4 0.0 3.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 KKK16592.1 - 0.31 11.4 0.1 0.31 11.4 0.1 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat WD40 PF00400.32 KKK16593.1 - 7.9e-47 156.3 22.8 7.9e-10 39.2 0.2 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKK16593.1 - 7.8e-09 35.7 0.4 0.06 13.6 0.0 4.5 3 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KKK16593.1 - 0.00029 19.6 4.6 0.63 8.6 0.1 4.6 1 1 5 6 6 6 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KKK16593.1 - 0.0017 17.4 0.1 2.5 7.0 0.0 3.8 2 2 2 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 KKK16593.1 - 0.014 14.0 0.1 1.5 7.3 0.0 2.2 2 0 0 2 2 2 0 Cytochrome D1 heme domain PD40 PF07676.12 KKK16593.1 - 0.02 14.8 0.1 22 5.1 0.0 4.1 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat WD40_like PF17005.5 KKK16593.1 - 0.03 13.6 0.0 5.3 6.3 0.0 2.8 2 1 0 3 3 3 0 WD40-like domain Sdh5 PF03937.16 KKK16594.1 - 1.9e-24 85.4 1.1 4.6e-24 84.2 0.5 2.0 3 0 0 3 3 3 1 Flavinator of succinate dehydrogenase Metallophos PF00149.28 KKK16599.1 - 2.4e-40 139.2 0.1 3.1e-40 138.9 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KKK16599.1 - 1.1e-22 80.1 2.7 1.4e-22 79.8 1.8 1.7 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain LRR_4 PF12799.7 KKK16600.1 - 1.2e-11 44.7 4.6 0.0023 18.3 0.1 4.2 4 0 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KKK16600.1 - 9.5e-11 41.3 10.7 3e-06 26.9 0.7 4.0 2 1 2 4 4 4 3 Leucine rich repeat LRR_9 PF14580.6 KKK16600.1 - 0.0023 17.5 0.9 0.038 13.5 0.7 2.3 1 1 1 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.33 KKK16600.1 - 0.11 13.2 8.5 24 6.0 0.2 5.6 5 1 0 5 5 5 0 Leucine Rich Repeat LRR_6 PF13516.6 KKK16600.1 - 0.66 10.2 10.8 1.7 8.9 0.5 4.9 6 0 0 6 6 6 0 Leucine Rich repeat DUF2457 PF10446.9 KKK16601.1 - 4.3e-144 481.2 37.7 4.3e-144 481.2 37.7 3.4 3 1 0 3 3 3 1 Protein of unknown function (DUF2457) Arf PF00025.21 KKK16601.1 - 1.1e-62 210.6 0.0 1.6e-62 210.0 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 KKK16601.1 - 5.7e-09 35.6 0.0 4.6e-06 26.0 0.0 2.4 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 KKK16601.1 - 5.8e-07 29.1 0.0 1.1e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KKK16601.1 - 9.7e-06 25.7 0.0 1.8e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 KKK16601.1 - 1e-05 25.7 0.0 3.3e-05 24.1 0.0 1.9 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KKK16601.1 - 0.00084 19.0 0.0 0.0015 18.1 0.0 1.4 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 KKK16601.1 - 0.0017 17.7 0.0 0.0027 17.1 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Abhydrolase_6 PF12697.7 KKK16602.1 - 0.00052 20.7 1.2 0.00065 20.4 1.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 KKK16602.1 - 0.0036 17.2 0.0 0.005 16.7 0.0 1.3 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase bZIP_1 PF00170.21 KKK16662.1 - 1.8e-05 24.7 8.1 1.8e-05 24.7 8.1 1.9 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 KKK16662.1 - 0.00057 19.9 8.8 0.0018 18.3 8.8 1.9 1 0 0 1 1 1 1 Basic region leucine zipper Stm1_N PF09598.10 KKK16663.1 - 1.8e-16 60.7 4.2 1.8e-16 60.7 4.2 4.6 3 1 0 3 3 3 1 Stm1 DUF3237 PF11578.8 KKK16664.1 - 3.8e-47 159.9 0.1 4.2e-47 159.7 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) AA_permease PF00324.21 KKK16665.1 - 2.6e-59 201.1 32.3 3.3e-59 200.7 32.3 1.1 1 0 0 1 1 1 1 Amino acid permease SLC12 PF03522.15 KKK16665.1 - 9.2e-22 77.6 0.8 1.7e-07 30.6 0.1 3.3 3 0 0 3 3 3 3 Solute carrier family 12 AA_permease_2 PF13520.6 KKK16665.1 - 2.3e-19 69.5 38.9 3.2e-19 69.1 38.9 1.1 1 0 0 1 1 1 1 Amino acid permease DUF5336 PF17270.2 KKK16666.1 - 7.2 6.2 7.1 3.2 7.3 3.1 2.3 2 1 0 2 2 2 0 Family of unknown function (DUF5336) UNC-93 PF05978.16 KKK16667.1 - 0.014 15.1 5.3 0.18 11.5 0.1 2.5 1 1 0 2 2 2 0 Ion channel regulatory protein UNC-93 FAD_binding_3 PF01494.19 KKK16668.1 - 3.3e-21 75.9 0.0 6.4e-21 75.0 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 KKK16668.1 - 0.073 12.3 0.7 4.6 6.4 0.2 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KKK16668.1 - 0.13 12.5 0.2 0.46 10.8 0.2 1.9 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain MFS_1 PF07690.16 KKK16669.1 - 3e-29 102.1 32.0 3e-29 102.1 32.0 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KKK16669.1 - 4.3e-09 35.7 9.9 4.3e-09 35.7 9.9 2.9 2 1 0 3 3 3 2 Sugar (and other) transporter Ribosomal_L7Ae PF01248.26 KKK16670.1 - 6.9e-23 80.2 0.0 8.5e-23 79.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 KKK16670.1 - 0.00038 20.6 0.0 0.00038 20.6 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 PELOTA_1 PF15608.6 KKK16670.1 - 0.0008 19.2 0.0 0.0011 18.8 0.0 1.2 1 0 0 1 1 1 1 PELOTA RNA binding domain Glyco_hydro_10 PF00331.20 KKK16671.1 - 7.1e-68 229.1 0.4 8.4e-68 228.8 0.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Abhydrolase_1 PF00561.20 KKK16672.1 - 6.6e-20 71.8 0.0 2.2e-19 70.1 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 KKK16672.1 - 3e-18 65.8 0.1 1.8e-17 63.3 0.0 2.2 3 0 0 3 3 3 1 TAP-like protein Fungal_trans PF04082.18 KKK16673.1 - 3.5e-11 42.7 1.2 7.1e-11 41.6 1.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain LSM PF01423.22 KKK16674.1 - 2.1e-19 68.9 0.1 2.6e-19 68.7 0.1 1.1 1 0 0 1 1 1 1 LSM domain Ribosomal_L5_C PF00673.21 KKK16675.1 - 1e-21 76.9 0.0 1.5e-21 76.4 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 KKK16675.1 - 2.7e-20 72.4 0.0 7.5e-20 71.0 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L5 Aa_trans PF01490.18 KKK16676.1 - 1.1e-83 281.2 30.7 1.5e-83 280.8 30.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein MPC PF03650.13 KKK16677.1 - 2.4e-36 124.2 0.0 2.9e-36 124.0 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers Phage_Coat_B PF05356.11 KKK16677.1 - 0.074 13.0 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Phage Coat protein B Clr5 PF14420.6 KKK16679.1 - 1.9e-12 47.2 0.9 3.4e-12 46.4 0.9 1.4 1 0 0 1 1 1 1 Clr5 domain SPX PF03105.19 KKK16679.1 - 0.0075 16.2 5.0 0.0095 15.9 5.0 1.2 1 0 0 1 1 1 1 SPX domain ADH_N PF08240.12 KKK16680.1 - 3.2e-06 27.0 0.0 7.5e-06 25.8 0.0 1.5 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Rdx PF10262.9 KKK16682.1 - 2.5e-13 50.0 0.0 3.4e-13 49.6 0.0 1.2 1 0 0 1 1 1 1 Rdx family Serglycin PF04360.12 KKK16682.1 - 0.47 10.4 7.8 0.72 9.8 7.8 1.3 1 0 0 1 1 1 0 Serglycin PDEase_I PF00233.19 KKK16683.1 - 1.7e-69 234.2 0.0 2.4e-69 233.7 0.0 1.2 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase HD PF01966.22 KKK16683.1 - 0.073 13.3 0.0 0.18 12.1 0.0 1.6 1 0 0 1 1 1 0 HD domain SHMT PF00464.19 KKK16684.1 - 7.1e-197 653.8 0.0 8.3e-197 653.6 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Patatin PF01734.22 KKK16685.1 - 1.7e-16 61.0 0.2 3.7e-16 59.9 0.1 1.6 2 0 0 2 2 2 1 Patatin-like phospholipase LysM PF01476.20 KKK16694.1 - 5.9e-13 48.7 0.3 2.4e-06 27.5 0.1 2.1 2 0 0 2 2 2 2 LysM domain Rubella_E2 PF05749.11 KKK16694.1 - 3.4 7.0 10.0 1.5 8.2 2.0 2.1 2 0 0 2 2 2 0 Rubella membrane glycoprotein E2 Actin PF00022.19 KKK16710.1 - 2.9e-150 500.4 0.0 1.1e-149 498.5 0.0 1.7 1 1 0 1 1 1 1 Actin Pet127 PF08634.10 KKK16711.1 - 1.3e-121 405.2 1.2 1.8e-121 404.8 1.2 1.2 1 0 0 1 1 1 1 Mitochondrial protein Pet127 GARS_A PF01071.19 KKK16712.1 - 3.3e-84 281.5 0.0 5.6e-84 280.8 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.15 KKK16712.1 - 3.8e-35 120.6 0.0 1.9e-34 118.3 0.0 2.3 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, N domain AIRS_C PF02769.22 KKK16712.1 - 5.5e-35 120.8 0.0 1.2e-34 119.7 0.0 1.5 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain GARS_C PF02843.16 KKK16712.1 - 2.6e-26 91.7 0.3 6.9e-26 90.4 0.3 1.8 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.24 KKK16712.1 - 4.7e-15 56.0 2.7 1.5e-14 54.4 2.7 1.9 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain CPSase_L_D2 PF02786.17 KKK16712.1 - 3.2e-05 23.5 0.0 5.9e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_3 PF02655.14 KKK16712.1 - 5.3e-05 23.3 0.0 0.00017 21.7 0.0 1.8 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp PF02222.22 KKK16712.1 - 5.6e-05 22.8 0.0 9.9e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.6 KKK16712.1 - 0.0014 18.3 0.0 0.024 14.2 0.0 2.2 2 0 0 2 2 2 1 ATP-grasp domain RimK PF08443.11 KKK16712.1 - 0.0066 16.1 0.0 0.017 14.7 0.0 1.7 2 0 0 2 2 2 1 RimK-like ATP-grasp domain SOAR PF16533.5 KKK16713.1 - 0.24 11.4 1.7 4.3 7.4 0.0 2.7 2 0 0 2 2 2 0 STIM1 Orai1-activating region FA_desaturase PF00487.24 KKK16714.1 - 2.2e-28 99.8 26.0 4.1e-28 98.9 26.0 1.4 1 1 0 1 1 1 1 Fatty acid desaturase DUF3431 PF11913.8 KKK16715.1 - 4.1e-69 232.6 0.0 4.8e-69 232.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) SNARE PF05739.19 KKK16717.1 - 1.6e-12 47.2 0.5 4.1e-12 45.9 0.1 2.0 2 0 0 2 2 2 1 SNARE domain Syntaxin-5_N PF11416.8 KKK16717.1 - 2.8e-10 39.1 0.0 5.9e-10 38.1 0.0 1.6 1 0 0 1 1 1 1 Syntaxin-5 N-terminal, Sly1p-binding domain KxDL PF10241.9 KKK16717.1 - 4.4e-05 23.7 0.5 0.16 12.3 0.1 2.9 2 0 0 2 2 2 2 Uncharacterized conserved protein Syntaxin PF00804.25 KKK16717.1 - 0.00076 19.2 2.9 0.0088 15.7 0.1 2.6 2 1 0 2 2 2 1 Syntaxin DUF4988 PF16378.5 KKK16717.1 - 0.019 14.6 1.4 11 5.6 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function Snapin_Pallidin PF14712.6 KKK16717.1 - 0.042 14.3 0.1 10 6.6 0.0 2.8 2 0 0 2 2 2 0 Snapin/Pallidin NPV_P10 PF05531.12 KKK16717.1 - 0.31 11.5 4.8 22 5.6 0.2 3.3 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein MCPsignal PF00015.21 KKK16717.1 - 0.36 10.6 6.6 0.49 10.2 1.1 2.6 2 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain SlyX PF04102.12 KKK16717.1 - 0.45 11.2 4.0 1.3 9.7 0.2 2.9 2 1 0 2 2 2 0 SlyX Peptidase_M50B PF13398.6 KKK16718.1 - 3.3e-28 98.7 16.7 3.3e-28 98.7 16.7 2.0 2 0 0 2 2 2 1 Peptidase M50B-like TMEM43 PF07787.12 KKK16718.1 - 6 6.2 5.1 12 5.2 5.1 1.5 1 0 0 1 1 1 0 Transmembrane protein 43 Patched PF02460.18 KKK16718.1 - 9.2 4.2 6.7 14 3.6 6.7 1.2 1 0 0 1 1 1 0 Patched family TctB PF07331.11 KKK16718.1 - 9.9 6.4 18.1 2.6 8.3 11.0 2.4 1 1 1 2 2 2 0 Tripartite tricarboxylate transporter TctB family DUF1275 PF06912.11 KKK16719.1 - 7.9e-35 120.5 7.7 8.9e-35 120.4 7.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) Pkinase PF00069.25 KKK16734.1 - 1.3e-62 211.6 0.0 1.6e-62 211.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK16734.1 - 1.8e-30 106.1 0.0 2.6e-30 105.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KKK16734.1 - 0.002 17.2 0.0 0.0026 16.8 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain zf-UBR PF02207.20 KKK16736.1 - 7e-14 51.8 4.6 7e-14 51.8 4.6 3.3 3 0 0 3 3 3 1 Putative zinc finger in N-recognin (UBR box) MCM_bind PF09739.9 KKK16736.1 - 0.75 8.2 3.0 1.1 7.7 3.0 1.2 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor CDC45 PF02724.14 KKK16736.1 - 3.9 5.6 5.8 7.3 4.7 5.8 1.4 1 0 0 1 1 1 0 CDC45-like protein MCM PF00493.23 KKK16737.1 - 8.6e-102 339.0 0.0 1.3e-101 338.3 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KKK16737.1 - 4.1e-39 133.3 0.4 7.7e-39 132.4 0.4 1.4 1 0 0 1 1 1 1 MCM OB domain MCM2_N PF12619.8 KKK16737.1 - 2.2e-25 89.7 41.7 2.2e-25 89.7 41.7 2.3 3 0 0 3 3 2 1 Mini-chromosome maintenance protein 2 MCM_lid PF17855.1 KKK16737.1 - 1.8e-24 85.9 1.4 3.1e-24 85.2 0.3 2.1 2 0 0 2 2 1 1 MCM AAA-lid domain MCM_N PF14551.6 KKK16737.1 - 3.7e-13 49.9 0.0 1.1e-12 48.5 0.0 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 KKK16737.1 - 3.8e-09 36.2 0.1 9.4e-07 28.4 0.0 2.5 1 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KKK16737.1 - 3.7e-06 27.0 0.0 7.8e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 KKK16737.1 - 0.00098 19.0 0.0 0.0046 16.8 0.0 2.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KKK16737.1 - 0.0035 17.1 0.2 0.024 14.3 0.2 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain Zn_ribbon_2 PF12674.7 KKK16737.1 - 0.069 13.8 0.7 0.18 12.5 0.7 1.7 1 0 0 1 1 1 0 Putative zinc ribbon domain zinc_ribbon_10 PF10058.9 KKK16737.1 - 0.24 11.1 1.3 0.49 10.2 1.3 1.5 1 0 0 1 1 1 0 Predicted integral membrane zinc-ribbon metal-binding protein zf-TFIIB PF13453.6 KKK16737.1 - 0.64 9.4 1.9 1.5 8.2 1.9 1.7 1 0 0 1 1 1 0 Transcription factor zinc-finger Pyr_redox_2 PF07992.14 KKK16738.1 - 3.1e-08 33.2 0.0 2.7e-07 30.1 0.0 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KKK16738.1 - 0.00033 20.8 0.0 0.0013 19.0 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain RecA_dep_nuc PF16786.5 KKK16738.1 - 0.014 15.5 0.0 0.05 13.8 0.0 1.8 2 0 0 2 2 2 0 Recombination enhancement, RecA-dependent nuclease FAD_binding_3 PF01494.19 KKK16738.1 - 0.025 13.8 0.0 0.046 13.0 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.6 KKK16738.1 - 0.029 14.4 0.0 0.11 12.4 0.0 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding HI0933_like PF03486.14 KKK16738.1 - 0.074 11.7 0.0 0.13 11.0 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein Cerato-platanin PF07249.12 KKK16739.1 - 2.6e-51 172.7 0.3 3.1e-51 172.5 0.3 1.0 1 0 0 1 1 1 1 Cerato-platanin MF_alpha_N PF05436.11 KKK16739.1 - 0.0051 16.7 0.2 0.0084 16.0 0.2 1.4 1 0 0 1 1 1 1 Mating factor alpha precursor N-terminus PH PF00169.29 KKK16740.1 - 0.1 13.1 0.0 0.67 10.5 0.0 2.4 2 1 0 2 2 2 0 PH domain Pkinase PF00069.25 KKK16742.1 - 1e-11 44.7 0.0 1e-06 28.3 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KKK16742.1 - 6.3e-08 32.2 0.0 0.0014 17.9 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 KKK16742.1 - 0.005 16.8 0.0 0.01 15.8 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KKK16742.1 - 0.02 14.2 0.0 0.51 9.6 0.0 2.1 2 0 0 2 2 2 0 Kinase-like Kdo PF06293.14 KKK16742.1 - 0.035 13.4 0.0 0.057 12.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Lectin_C PF00059.21 KKK16744.1 - 0.0014 19.3 1.8 0.0016 19.2 0.7 1.7 2 0 0 2 2 2 1 Lectin C-type domain Sec62 PF03839.16 KKK16746.1 - 6.2e-76 254.7 0.6 6.2e-76 254.7 0.6 1.8 2 0 0 2 2 2 1 Translocation protein Sec62 BTRD1 PF17660.1 KKK16746.1 - 0.0098 15.7 0.4 2.1 8.2 0.1 2.5 1 1 1 2 2 2 2 Bacterial tandem repeat domain 1 TFIIA PF03153.13 KKK16746.1 - 4.4 7.2 21.5 7.1 6.5 21.5 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ribosomal_S21e PF01249.18 KKK16747.1 - 2.7e-41 139.5 0.1 2.8e-40 136.3 0.1 2.5 3 0 0 3 3 3 1 Ribosomal protein S21e NUDIX PF00293.28 KKK16747.1 - 9.7e-07 28.9 0.0 3.8e-06 27.0 0.0 2.0 2 1 0 2 2 2 1 NUDIX domain tRNA-synt_2d PF01409.20 KKK16748.1 - 3.1e-88 295.4 0.0 4.2e-88 295.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) PheRS_DBD3 PF18553.1 KKK16748.1 - 8.9e-15 54.7 0.7 1.6e-14 53.9 0.1 1.8 2 0 0 2 2 2 1 PheRS DNA binding domain 3 tRNA_synthFbeta PF17759.1 KKK16748.1 - 1.1e-06 28.2 0.0 0.011 15.2 0.0 2.3 2 0 0 2 2 2 2 Phenylalanyl tRNA synthetase beta chain CLM domain tRNA-synt_2 PF00152.20 KKK16748.1 - 2.9e-05 23.3 0.4 0.0023 17.1 0.0 3.3 4 0 0 4 4 4 1 tRNA synthetases class II (D, K and N) PheRS_DBD2 PF18554.1 KKK16748.1 - 0.0011 18.9 2.2 0.0032 17.4 2.2 1.9 1 0 0 1 1 1 1 PheRS DNA binding domain 2 tRNA-synt_2b PF00587.25 KKK16748.1 - 0.16 11.9 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 tRNA synthetase class II core domain (G, H, P, S and T) EAF PF09816.9 KKK16762.1 - 6.6e-19 68.2 0.3 1.7e-18 66.8 0.3 1.8 1 0 0 1 1 1 1 RNA polymerase II transcription elongation factor Cyclin_N PF00134.23 KKK16762.1 - 2.3e-14 53.2 0.1 5.8e-14 51.9 0.1 1.7 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KKK16762.1 - 0.00012 22.2 4.2 0.0014 18.7 0.0 3.6 3 1 1 4 4 4 1 Cyclin, C-terminal domain TFIIB PF00382.19 KKK16762.1 - 0.0048 16.9 3.3 0.39 10.8 0.0 2.5 2 0 0 2 2 2 2 Transcription factor TFIIB repeat DUF3246 PF11596.8 KKK16762.1 - 0.36 10.2 4.5 0.89 8.9 4.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) Dor1 PF04124.12 KKK16763.1 - 5.7e-52 176.5 3.5 5.1e-41 140.5 4.1 2.3 2 0 0 2 2 2 2 Dor1-like family Vps51 PF08700.11 KKK16763.1 - 0.0002 21.4 0.5 0.0002 21.4 0.5 2.1 2 0 0 2 2 2 1 Vps51/Vps67 COG2 PF06148.11 KKK16763.1 - 0.062 13.4 1.7 0.14 12.3 0.8 2.0 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 His_Phos_1 PF00300.22 KKK16764.1 - 5.5e-28 98.0 1.2 6.7e-28 97.7 0.0 1.7 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) FolB PF02152.18 KKK16765.1 - 2.1e-26 92.7 0.1 1.3e-22 80.5 0.3 2.4 2 0 0 2 2 2 2 Dihydroneopterin aldolase Fungal_trans_2 PF11951.8 KKK16767.1 - 2.5e-18 66.1 0.6 5.4e-14 51.8 0.1 3.1 3 0 0 3 3 3 3 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK16767.1 - 4.5e-07 29.9 11.5 4.5e-07 29.9 11.5 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KKK16767.1 - 0.091 11.8 0.4 0.18 10.8 0.4 1.5 1 1 0 1 1 1 0 Fungal specific transcription factor domain BAR_2 PF10455.9 KKK16768.1 - 1.4e-14 53.9 0.3 1.6e-14 53.8 0.3 1.0 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.18 KKK16768.1 - 0.0044 16.7 0.1 0.0046 16.6 0.1 1.1 1 0 0 1 1 1 1 BAR domain DASH_Dam1 PF08653.10 KKK16768.1 - 0.11 12.4 0.1 0.35 10.7 0.0 1.8 1 1 1 2 2 2 0 DASH complex subunit Dam1 GCP_N_terminal PF17681.1 KKK16769.1 - 1.4e-66 225.3 0.0 2.1e-66 224.6 0.0 1.3 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 KKK16769.1 - 3.5e-62 210.6 2.6 7.1e-62 209.6 2.6 1.5 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal CLZ PF16526.5 KKK16769.1 - 0.33 11.3 3.8 0.35 11.3 0.3 2.8 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Methyltransf_11 PF08241.12 KKK16770.1 - 1.8e-10 41.3 0.0 3.2e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KKK16770.1 - 2.4e-10 40.5 0.0 3.5e-10 40.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKK16770.1 - 2e-09 38.1 0.0 7e-09 36.3 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KKK16770.1 - 6.1e-07 30.1 0.0 1.8e-06 28.6 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KKK16770.1 - 1.6e-06 28.0 0.3 3.3e-05 23.7 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.17 KKK16770.1 - 3.6e-05 23.3 0.0 0.0002 20.9 0.0 2.0 2 0 0 2 2 2 1 Putative methyltransferase Ubie_methyltran PF01209.18 KKK16770.1 - 0.0077 15.6 0.0 0.092 12.1 0.0 2.1 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family FtsJ PF01728.19 KKK16770.1 - 0.015 15.4 0.0 0.044 13.9 0.0 1.7 2 0 0 2 2 2 0 FtsJ-like methyltransferase Methyltransf_8 PF05148.15 KKK16770.1 - 0.1 12.4 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Hypothetical methyltransferase Methyltransf_2 PF00891.18 KKK16770.1 - 0.15 11.3 0.0 1.3 8.3 0.0 2.0 2 0 0 2 2 2 0 O-methyltransferase domain Methyltransf_8 PF05148.15 KKK16771.1 - 1.8e-53 181.7 0.0 2.5e-51 174.6 0.0 2.6 3 0 0 3 3 3 1 Hypothetical methyltransferase Methyltransf_11 PF08241.12 KKK16771.1 - 2.1e-07 31.5 0.0 1.2e-06 29.1 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKK16771.1 - 5e-06 27.1 0.0 0.00034 21.2 0.0 2.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 KKK16771.1 - 0.016 15.2 0.0 0.016 15.2 0.0 3.2 3 1 0 3 3 3 0 Methyltransferase domain Methyltransf_31 PF13847.6 KKK16771.1 - 0.021 14.6 0.1 2.1 8.1 0.1 2.5 1 1 0 1 1 1 0 Methyltransferase domain Proteasome PF00227.26 KKK16772.1 - 3.7e-53 179.8 0.0 4.7e-53 179.5 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KKK16772.1 - 2.1e-09 36.9 0.1 5.6e-09 35.5 0.0 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature KH_8 PF17903.1 KKK16773.1 - 2.3e-31 107.7 0.0 5.9e-31 106.4 0.0 1.7 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 KKK16773.1 - 0.014 15.2 0.1 0.043 13.7 0.0 2.0 2 0 0 2 2 2 0 KH domain Paf1 PF03985.13 KKK16773.1 - 0.3 10.0 20.9 0.43 9.5 20.9 1.1 1 0 0 1 1 1 0 Paf1 ATG22 PF11700.8 KKK16774.1 - 7.4e-128 427.2 24.0 8.6e-128 426.9 24.0 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.16 KKK16774.1 - 4.1e-13 49.0 21.7 3.3e-08 32.8 8.0 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily Proton_antipo_N PF00662.20 KKK16774.1 - 0.24 11.5 3.6 0.27 11.3 0.2 2.8 2 0 0 2 2 2 0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus DUF2678 PF10856.8 KKK16774.1 - 1.2 9.1 6.6 0.8 9.7 0.3 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF2678) E1_DerP2_DerF2 PF02221.15 KKK16775.1 - 8.3e-32 110.4 0.1 1.1e-31 110.1 0.1 1.1 1 0 0 1 1 1 1 ML domain Big_9 PF17963.1 KKK16775.1 - 0.00014 22.6 0.0 0.00023 21.8 0.0 1.4 1 0 0 1 1 1 1 Bacterial Ig domain Cadherin_4 PF17803.1 KKK16775.1 - 0.0032 18.1 0.1 0.0054 17.3 0.1 1.4 1 0 0 1 1 1 1 Bacterial cadherin-like domain Alph_Pro_TM PF09608.10 KKK16775.1 - 0.11 12.3 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Putative transmembrane protein (Alph_Pro_TM) NPCBM_assoc PF10633.9 KKK16775.1 - 0.13 12.5 0.0 2.5 8.4 0.0 2.4 2 0 0 2 2 2 0 NPCBM-associated, NEW3 domain of alpha-galactosidase Thiolase_N PF00108.23 KKK16776.1 - 2e-64 217.5 1.1 3.6e-64 216.6 1.1 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KKK16776.1 - 2.1e-39 134.0 0.1 4.4e-39 132.9 0.1 1.5 1 0 0 1 1 1 1 Thiolase, C-terminal domain HNH_2 PF13391.6 KKK16776.1 - 8.9e-12 45.0 0.3 1.9e-11 43.9 0.3 1.6 1 0 0 1 1 1 1 HNH endonuclease ketoacyl-synt PF00109.26 KKK16776.1 - 0.0027 17.3 1.2 0.011 15.3 1.1 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 KKK16776.1 - 0.012 15.5 0.8 0.43 10.5 0.2 2.4 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III AMP-binding PF00501.28 KKK16777.1 - 1.2e-45 155.8 0.0 7.1e-45 153.3 0.0 1.9 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KKK16777.1 - 0.00079 20.4 0.1 0.0018 19.2 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Methyltransf_23 PF13489.6 KKK16778.1 - 1.2e-39 135.8 0.0 1.7e-39 135.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKK16778.1 - 7.2e-08 33.0 0.0 1.5e-06 28.8 0.0 2.7 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KKK16778.1 - 2e-06 28.5 0.0 4.8e-06 27.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KKK16778.1 - 2.3e-05 25.0 0.0 0.00026 21.6 0.0 2.5 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KKK16778.1 - 0.0053 16.6 0.0 0.017 14.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain DAO PF01266.24 KKK16779.1 - 1.4e-46 159.7 0.2 1.6e-46 159.5 0.2 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KKK16779.1 - 2.2e-08 33.7 0.0 0.0032 16.7 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KKK16779.1 - 5.7e-07 28.9 0.0 3.3e-06 26.4 0.0 1.9 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_9 PF13454.6 KKK16779.1 - 9.8e-07 28.9 0.2 0.016 15.2 0.2 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 KKK16779.1 - 9.8e-07 28.1 0.0 0.0041 16.2 0.0 2.1 2 0 0 2 2 2 2 Lycopene cyclase protein FAD_binding_2 PF00890.24 KKK16779.1 - 1.8e-05 24.0 0.0 0.025 13.7 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain Trp_halogenase PF04820.14 KKK16779.1 - 3.2e-05 23.0 0.0 0.085 11.7 0.0 2.2 2 0 0 2 2 2 2 Tryptophan halogenase NAD_binding_8 PF13450.6 KKK16779.1 - 0.00011 22.3 0.0 0.00029 21.0 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KKK16779.1 - 0.00093 19.7 0.0 0.02 15.4 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KKK16779.1 - 0.0021 17.4 0.0 0.39 10.0 0.0 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Thi4 PF01946.17 KKK16779.1 - 0.0082 15.4 0.0 0.018 14.3 0.0 1.5 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 KKK16779.1 - 0.018 13.8 0.1 4.5 5.9 0.1 2.2 2 0 0 2 2 2 0 HI0933-like protein GMC_oxred_N PF00732.19 KKK16779.1 - 0.022 14.1 0.0 0.18 11.2 0.0 2.0 2 0 0 2 2 2 0 GMC oxidoreductase FAD_binding_3 PF01494.19 KKK16779.1 - 0.051 12.8 0.1 0.97 8.6 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain TBP PF00352.21 KKK16780.1 - 1.4e-67 223.6 0.1 9.7e-33 112.0 0.1 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 KKK16780.1 - 6.8e-05 22.9 0.0 0.23 11.6 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) DUF4295 PF14128.6 KKK16780.1 - 0.14 12.0 0.1 0.71 9.7 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4295) F-box PF00646.33 KKK16781.1 - 7.1e-05 22.6 0.0 0.0002 21.1 0.0 1.9 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KKK16781.1 - 8.7e-05 22.3 0.1 0.00021 21.1 0.1 1.7 1 0 0 1 1 1 1 F-box-like MTP18 PF10558.9 KKK16782.1 - 0.0031 17.5 0.0 0.85 9.6 0.0 2.4 2 0 0 2 2 2 2 Mitochondrial 18 KDa protein (MTP18) SpoIIE PF07228.12 KKK16783.1 - 0.0023 17.9 0.1 0.005 16.8 0.1 1.6 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.21 KKK16783.1 - 0.0097 15.6 0.0 0.014 15.0 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C WD40 PF00400.32 KKK16784.1 - 7.4e-47 156.4 26.1 4e-06 27.5 0.4 12.4 12 0 0 12 12 12 9 WD domain, G-beta repeat Utp12 PF04003.12 KKK16784.1 - 8.1e-22 77.6 0.4 1.9e-21 76.4 0.4 1.6 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 KKK16784.1 - 1.9e-18 66.5 3.8 0.0035 17.6 0.0 9.0 7 3 3 11 11 11 6 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KKK16784.1 - 1.5e-08 34.0 3.5 0.034 13.1 0.1 4.9 2 1 0 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KKK16784.1 - 0.0003 20.2 0.0 1.1 8.6 0.0 3.7 3 0 0 3 3 3 2 WD40-like domain Nup160 PF11715.8 KKK16784.1 - 0.00043 19.1 3.1 0.49 9.0 0.0 5.0 6 1 0 6 6 6 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 KKK16784.1 - 0.00094 18.0 2.0 0.64 8.7 0.0 4.3 2 1 2 4 4 4 1 Nup133 N terminal like Frtz PF11768.8 KKK16784.1 - 0.016 13.6 0.0 0.12 10.7 0.0 2.1 2 1 1 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz PALB2_WD40 PF16756.5 KKK16784.1 - 0.12 11.2 1.6 17 4.2 0.2 3.4 4 0 0 4 4 4 0 Partner and localizer of BRCA2 WD40 domain P34-Arc PF04045.14 KKK16785.1 - 1.1e-106 355.9 0.1 1.3e-106 355.7 0.1 1.0 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc Kinesin PF00225.23 KKK16786.1 - 1.5e-90 303.5 0.1 1.5e-90 303.5 0.1 2.6 3 0 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 KKK16786.1 - 1.6e-17 63.9 0.0 6.6e-14 52.1 0.0 3.0 1 1 1 2 2 2 2 Microtubule binding DUF2937 PF11157.8 KKK16786.1 - 3.8 7.2 16.0 0.25 11.0 3.6 4.1 3 1 0 3 3 3 0 Protein of unknown function (DUF2937) Peptidase_C48 PF02902.19 KKK16789.1 - 2.2e-25 89.8 0.0 4.3e-25 88.8 0.0 1.5 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Glyco_hydro_16 PF00722.21 KKK16790.1 - 0.0078 15.7 0.3 0.045 13.2 0.1 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 PALP PF00291.25 KKK16791.1 - 1.8e-12 47.3 2.0 2.6e-11 43.5 0.2 2.3 1 1 1 2 2 2 2 Pyridoxal-phosphate dependent enzyme LPP PF04728.13 KKK16792.1 - 1.1e-05 25.7 5.3 0.012 16.0 0.7 3.6 2 1 1 3 3 3 1 Lipoprotein leucine-zipper DUF1664 PF07889.12 KKK16792.1 - 0.0003 20.8 1.9 0.0011 19.0 1.3 2.2 2 1 0 2 2 2 1 Protein of unknown function (DUF1664) DUF4618 PF15397.6 KKK16792.1 - 0.00041 19.8 2.9 0.18 11.2 0.4 2.8 1 1 2 3 3 3 2 Domain of unknown function (DUF4618) HMMR_N PF15905.5 KKK16792.1 - 0.0006 19.4 1.4 0.0012 18.4 0.8 1.7 1 1 1 2 2 2 1 Hyaluronan mediated motility receptor N-terminal CENP-F_leu_zip PF10473.9 KKK16792.1 - 0.001 19.1 5.2 0.046 13.7 0.5 2.8 2 1 1 3 3 3 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF641 PF04859.12 KKK16792.1 - 0.0012 19.2 1.9 0.1 13.0 0.3 2.4 1 1 1 2 2 2 1 Plant protein of unknown function (DUF641) Spc7 PF08317.11 KKK16792.1 - 0.0017 17.3 1.6 0.0027 16.7 1.6 1.4 1 0 0 1 1 1 1 Spc7 kinetochore protein AAA_13 PF13166.6 KKK16792.1 - 0.003 16.3 0.2 0.0061 15.3 0.1 1.4 1 1 0 1 1 1 1 AAA domain ATG16 PF08614.11 KKK16792.1 - 0.0063 16.8 2.8 0.0063 16.8 2.8 1.9 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) TSC22 PF01166.18 KKK16792.1 - 0.0067 16.7 0.1 0.37 11.1 0.0 2.7 1 1 1 2 2 2 1 TSC-22/dip/bun family AIP3 PF03915.13 KKK16792.1 - 0.008 15.3 2.6 0.015 14.4 2.6 1.5 1 0 0 1 1 1 1 Actin interacting protein 3 EzrA PF06160.12 KKK16792.1 - 0.019 13.1 0.1 0.037 12.2 0.1 1.3 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA Mto2_bdg PF12808.7 KKK16792.1 - 0.024 14.9 0.3 0.38 11.1 0.0 2.8 3 0 0 3 3 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region Plasmid_RAQPRD PF09686.10 KKK16792.1 - 0.029 14.6 0.8 1.9 8.7 0.1 2.7 1 1 0 2 2 2 0 Plasmid protein of unknown function (Plasmid_RAQPRD) Atg14 PF10186.9 KKK16792.1 - 0.044 12.9 3.8 0.024 13.7 0.7 1.9 1 1 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Prominin PF05478.11 KKK16792.1 - 0.045 11.7 3.5 0.095 10.6 3.3 1.4 1 1 0 1 1 1 0 Prominin COG7 PF10191.9 KKK16792.1 - 0.055 11.7 1.7 0.37 9.0 1.2 1.9 1 1 1 2 2 2 0 Golgi complex component 7 (COG7) NPV_P10 PF05531.12 KKK16792.1 - 0.064 13.7 5.2 0.19 12.2 0.9 3.1 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Bacillus_HBL PF05791.11 KKK16792.1 - 0.082 12.7 0.4 0.12 12.2 0.4 1.2 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) Seryl_tRNA_N PF02403.22 KKK16792.1 - 0.088 13.0 0.2 0.19 11.9 0.2 1.6 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Fib_alpha PF08702.10 KKK16792.1 - 0.1 12.8 1.5 0.82 9.8 0.9 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Tropomyosin_1 PF12718.7 KKK16792.1 - 0.11 12.7 0.1 0.34 11.0 0.1 1.9 1 1 0 1 1 1 0 Tropomyosin like CLZ PF16526.5 KKK16792.1 - 0.11 12.9 4.6 19 5.7 0.1 3.6 1 1 2 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels KASH_CCD PF14662.6 KKK16792.1 - 0.14 12.0 3.4 0.33 10.7 0.8 2.1 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH ADIP PF11559.8 KKK16792.1 - 0.15 12.1 3.5 1.7 8.7 0.6 2.3 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Vps51 PF08700.11 KKK16792.1 - 0.18 11.9 2.1 36 4.5 0.1 3.4 2 1 1 3 3 3 0 Vps51/Vps67 DUF5082 PF16888.5 KKK16792.1 - 0.23 11.7 1.6 1.4 9.2 0.3 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) DUF1640 PF07798.11 KKK16792.1 - 0.29 11.1 4.7 44 4.1 4.5 2.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) MscS_porin PF12795.7 KKK16792.1 - 0.3 10.6 0.1 0.3 10.6 0.1 2.1 2 1 0 2 2 2 0 Mechanosensitive ion channel porin domain FlaC_arch PF05377.11 KKK16792.1 - 0.32 11.4 1.2 8 6.9 0.5 3.2 2 1 0 2 2 1 0 Flagella accessory protein C (FlaC) COG5 PF10392.9 KKK16792.1 - 0.33 11.1 9.0 0.26 11.5 1.0 3.4 1 1 3 4 4 4 0 Golgi transport complex subunit 5 Baculo_PEP_C PF04513.12 KKK16792.1 - 0.41 10.7 6.1 0.072 13.1 1.9 1.8 2 1 0 2 2 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Syntaxin_2 PF14523.6 KKK16792.1 - 0.69 10.3 4.5 0.2 12.1 1.0 1.9 2 1 0 2 2 2 0 Syntaxin-like protein Fez1 PF06818.15 KKK16792.1 - 0.72 10.3 6.3 0.3 11.5 0.5 2.4 2 1 1 3 3 2 0 Fez1 FAM76 PF16046.5 KKK16792.1 - 8.3 5.7 8.4 2.8 7.2 2.1 2.5 2 1 1 3 3 3 0 FAM76 protein PAP2 PF01569.21 KKK16793.1 - 2.7e-14 53.1 4.2 2.7e-14 53.1 4.2 2.1 2 0 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 KKK16793.1 - 0.0021 17.8 2.0 0.0021 17.8 2.0 2.4 2 1 1 3 3 3 1 PAP2 superfamily zf-HIT PF04438.16 KKK16794.1 - 2.8e-10 39.9 9.9 4.6e-10 39.2 9.9 1.3 1 0 0 1 1 1 1 HIT zinc finger RhoGAP PF00620.27 KKK16796.1 - 4.2e-37 127.3 0.5 8.6e-37 126.3 0.5 1.5 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.22 KKK16796.1 - 7e-29 99.8 35.1 1.8e-11 44.0 5.3 4.7 5 0 0 5 5 5 4 LIM domain zf_C2H2_13 PF18508.1 KKK16796.1 - 0.17 11.5 1.8 0.29 10.8 0.1 2.3 2 0 0 2 2 2 0 Zinc finger domain Desulfoferrod_N PF06397.12 KKK16796.1 - 0.17 11.5 2.8 0.14 11.8 0.4 2.2 2 0 0 2 2 2 0 Desulfoferrodoxin, N-terminal domain UQ_con PF00179.26 KKK16797.1 - 2e-28 98.8 0.1 8.8e-16 57.8 0.0 3.1 2 1 0 2 2 2 2 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KKK16797.1 - 9.9e-05 22.1 0.0 0.36 10.5 0.0 3.0 3 1 0 3 3 3 2 Prokaryotic E2 family B 3Beta_HSD PF01073.19 KKK16798.1 - 1.8e-41 142.0 0.7 1.3e-24 86.7 0.0 2.9 2 1 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KKK16798.1 - 1e-15 57.8 0.1 1.2e-09 38.1 0.0 2.8 2 1 0 2 2 2 2 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KKK16798.1 - 4e-08 33.0 0.0 0.00036 20.0 0.0 3.7 4 0 0 4 4 4 2 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 KKK16798.1 - 2.7e-07 30.0 0.0 0.00018 20.7 0.0 2.5 2 1 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.17 KKK16798.1 - 4.7e-05 22.6 0.0 0.013 14.6 0.0 2.8 2 1 0 2 2 2 2 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 KKK16798.1 - 0.011 14.9 0.0 0.14 11.2 0.0 2.0 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein VWA_2 PF13519.6 KKK16799.1 - 6.6e-21 75.0 0.1 2.2e-20 73.3 0.0 1.8 2 0 0 2 2 2 1 von Willebrand factor type A domain Ssl1 PF04056.14 KKK16799.1 - 4e-05 23.5 0.1 5.8e-05 23.0 0.1 1.2 1 0 0 1 1 1 1 Ssl1-like VWA PF00092.28 KKK16799.1 - 0.00066 20.0 0.3 0.001 19.4 0.3 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain UIM PF02809.20 KKK16799.1 - 0.032 14.1 0.1 0.11 12.4 0.1 2.0 1 0 0 1 1 1 0 Ubiquitin interaction motif DUF1194 PF06707.11 KKK16799.1 - 0.13 11.4 0.0 0.21 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1194) Nbl1_Borealin_N PF10444.9 KKK16800.1 - 1.9e-19 69.0 5.8 3.6e-19 68.1 5.8 1.5 1 0 0 1 1 1 1 Nbl1 / Borealin N terminal TRP PF06011.12 KKK16801.1 - 8.4e-142 472.8 10.6 1.1e-141 472.5 10.6 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 KKK16801.1 - 2.5e-39 134.8 0.2 4e-39 134.2 0.2 1.3 1 0 0 1 1 1 1 ML-like domain ETRAMP PF09716.10 KKK16801.1 - 2.3 8.3 0.0 2.3 8.3 0.0 2.9 4 0 0 4 4 4 0 Malarial early transcribed membrane protein (ETRAMP) DUF2663 PF10864.8 KKK16801.1 - 8.5 6.8 9.2 2 8.8 0.7 3.1 2 1 2 4 4 4 0 Protein of unknown function (DUF2663) GTP_CH_N PF12471.8 KKK16802.1 - 1.1e-89 299.3 0.0 1.4e-89 298.9 0.0 1.1 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.20 KKK16802.1 - 7.3e-12 45.2 0.0 1.1e-11 44.6 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase II NTP_transf_9 PF04248.12 KKK16802.1 - 0.059 13.3 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF427) GTP_cyclohydro2 PF00925.20 KKK16803.1 - 0.066 12.8 0.0 0.085 12.4 0.0 1.2 1 0 0 1 1 1 0 GTP cyclohydrolase II Ferric_reduct PF01794.19 KKK16804.1 - 1.1e-21 77.2 12.7 3.4e-21 75.7 12.7 1.9 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KKK16804.1 - 4.1e-16 59.5 0.0 1.5e-15 57.6 0.0 1.9 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KKK16804.1 - 3.1e-13 49.8 0.0 2.1e-10 40.6 0.0 2.7 2 0 0 2 2 2 2 FAD-binding domain NAD_binding_1 PF00175.21 KKK16804.1 - 0.025 15.2 0.2 1.5 9.5 0.0 2.3 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain DUF4153 PF13687.6 KKK16804.1 - 1.3 8.6 17.8 0.24 11.0 12.4 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4153) DHDPS PF00701.22 KKK16805.1 - 4.2e-38 130.7 0.0 5.5e-38 130.3 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family DUF2014 PF09427.10 KKK16806.1 - 1.9e-99 332.3 0.0 3e-99 331.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF2014) HLH PF00010.26 KKK16806.1 - 5.5e-18 64.7 0.1 1.3e-17 63.5 0.1 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain bZIP_1 PF00170.21 KKK16806.1 - 0.01 15.9 2.9 0.011 15.8 1.0 2.0 2 0 0 2 2 2 0 bZIP transcription factor ZapB PF06005.12 KKK16806.1 - 0.11 13.0 1.5 0.21 12.0 0.3 2.1 2 0 0 2 2 2 0 Cell division protein ZapB PBP PF01161.20 KKK16807.1 - 2.6e-19 69.9 0.0 3.4e-19 69.5 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Copper-fist PF00649.18 KKK16808.1 - 1.7e-14 53.0 2.8 3e-14 52.2 2.8 1.4 1 0 0 1 1 1 1 Copper fist DNA binding domain Glyco_hydro_72 PF03198.14 KKK16809.1 - 4.4e-139 463.1 5.7 5.2e-139 462.9 5.7 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.18 KKK16809.1 - 2.9e-06 26.9 0.1 2.3e-05 24.0 0.1 2.2 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DEAD PF00270.29 KKK16810.1 - 5.3e-34 117.5 0.3 1.8e-33 115.8 0.1 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KKK16810.1 - 2.4e-23 82.6 0.2 7.4e-23 81.0 0.2 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_30 PF13604.6 KKK16810.1 - 0.0066 16.2 0.1 0.016 14.9 0.0 1.6 2 0 0 2 2 2 1 AAA domain SH3_9 PF14604.6 KKK16811.1 - 6.5e-25 86.8 0.3 2e-12 46.8 0.1 2.4 2 0 0 2 2 2 2 Variant SH3 domain FCH PF00611.23 KKK16811.1 - 7.3e-23 80.7 0.2 2.5e-22 78.9 0.0 2.1 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.28 KKK16811.1 - 4.6e-18 64.5 0.1 2.6e-08 33.4 0.0 2.4 2 0 0 2 2 2 2 SH3 domain C1_1 PF00130.22 KKK16811.1 - 1.4e-15 56.9 5.2 2.8e-15 56.0 5.2 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SH3_10 PF17902.1 KKK16811.1 - 0.00011 22.2 0.0 0.36 10.9 0.0 2.8 2 0 0 2 2 2 2 SH3 domain C1_2 PF03107.16 KKK16811.1 - 0.00021 21.5 3.3 0.00041 20.6 3.3 1.4 1 0 0 1 1 1 1 C1 domain SH3_2 PF07653.17 KKK16811.1 - 0.0024 17.5 0.0 0.12 12.0 0.0 2.4 2 0 0 2 2 2 1 Variant SH3 domain SH3_3 PF08239.11 KKK16811.1 - 0.012 15.9 0.2 0.12 12.6 0.0 2.3 2 0 0 2 2 2 0 Bacterial SH3 domain FYVE PF01363.21 KKK16811.1 - 0.13 12.5 3.1 0.29 11.3 3.1 1.5 1 0 0 1 1 1 0 FYVE zinc finger Cortex-I_coil PF09304.10 KKK16811.1 - 2 8.7 15.5 1.1 9.5 0.0 4.0 4 0 0 4 4 4 0 Cortexillin I, coiled coil Ras PF00071.22 KKK16823.1 - 4.9e-18 65.3 0.0 1.6e-17 63.6 0.0 1.7 1 1 0 1 1 1 1 Ras family Roc PF08477.13 KKK16823.1 - 1.7e-05 25.0 0.0 3e-05 24.2 0.0 1.4 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 KKK16823.1 - 0.00039 19.7 0.0 0.00039 19.7 0.0 1.1 1 0 0 1 1 1 1 G-protein alpha subunit MCM PF00493.23 KKK16823.1 - 0.0023 17.1 0.0 0.0032 16.6 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain NACHT PF05729.12 KKK16823.1 - 0.015 15.2 0.1 0.025 14.5 0.1 1.3 1 0 0 1 1 1 0 NACHT domain AAA_21 PF13304.6 KKK16823.1 - 0.017 15.0 0.1 0.025 14.4 0.1 1.2 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KKK16823.1 - 0.043 14.2 0.0 0.046 14.1 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 KKK16823.1 - 0.048 14.2 0.0 0.057 13.9 0.0 1.3 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 KKK16823.1 - 0.05 13.3 0.1 0.12 12.1 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA_helicase PF00910.22 KKK16823.1 - 0.074 13.4 0.1 0.27 11.6 0.1 1.8 1 1 0 1 1 1 0 RNA helicase AAA_25 PF13481.6 KKK16823.1 - 0.078 12.5 0.2 1.5 8.3 0.1 2.1 2 0 0 2 2 2 0 AAA domain KAP_NTPase PF07693.14 KKK16823.1 - 0.091 12.0 0.0 0.12 11.5 0.0 1.1 1 0 0 1 1 1 0 KAP family P-loop domain Zeta_toxin PF06414.12 KKK16823.1 - 0.14 11.4 0.0 0.26 10.6 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_24 PF13479.6 KKK16823.1 - 0.22 11.2 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain PseudoU_synth_1 PF01416.20 KKK16824.1 - 5.5e-35 120.1 0.0 8.4e-34 116.3 0.0 2.7 2 1 0 2 2 2 1 tRNA pseudouridine synthase Dynamitin PF04912.14 KKK16824.1 - 0.017 14.5 0.2 0.025 13.9 0.2 1.2 1 0 0 1 1 1 0 Dynamitin Nop PF01798.18 KKK16825.1 - 6.1e-83 277.8 0.1 1.3e-82 276.7 0.1 1.6 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 KKK16825.1 - 5.5e-22 77.9 3.0 5.5e-22 77.9 3.0 2.4 2 0 0 2 2 2 1 NOP5NT (NUC127) domain HWE_HK PF07536.14 KKK16825.1 - 0.057 14.1 1.0 42 4.9 0.0 3.5 3 0 0 3 3 3 0 HWE histidine kinase PI3K_1B_p101 PF10486.9 KKK16825.1 - 3.5 5.3 9.3 6.7 4.3 9.3 1.4 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit RNA_pol_Rpb4 PF03874.16 KKK16826.1 - 1.6e-07 31.7 0.0 0.00089 19.6 0.0 2.4 2 1 0 2 2 2 2 RNA polymerase Rpb4 Pribosyltran_N PF13793.6 KKK16827.1 - 2e-32 111.5 0.0 4e-32 110.6 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 KKK16827.1 - 4.7e-31 108.3 3.3 2.6e-26 92.8 1.2 2.3 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 KKK16827.1 - 5.4e-14 52.0 0.6 1e-13 51.1 0.6 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 KKK16827.1 - 0.0048 16.4 0.3 0.0082 15.6 0.3 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase vATP-synt_AC39 PF01992.16 KKK16828.1 - 4.2e-103 345.4 0.0 4.8e-103 345.2 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit UCH PF00443.29 KKK16829.1 - 3e-47 161.3 0.0 4e-47 160.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KKK16829.1 - 9.7e-19 68.1 0.0 9.9e-18 64.8 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 KKK16829.1 - 0.00015 22.0 1.5 0.00037 20.8 0.3 2.4 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein zf-LYAR PF08790.11 KKK16829.1 - 0.045 13.7 0.1 0.18 11.8 0.1 2.2 1 0 0 1 1 1 0 LYAR-type C2HC zinc finger CRAL_TRIO PF00650.20 KKK16831.1 - 2.6e-25 89.0 0.0 4.8e-25 88.1 0.0 1.5 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KKK16831.1 - 1.7e-14 53.7 1.1 2.6e-14 53.2 0.2 1.8 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain DASH_Dam1 PF08653.10 KKK16832.1 - 2.2e-29 101.0 2.3 2.9e-29 100.6 2.3 1.2 1 0 0 1 1 1 1 DASH complex subunit Dam1 Ribosomal_60s PF00428.19 KKK16832.1 - 0.026 15.1 0.1 0.042 14.4 0.1 1.2 1 0 0 1 1 1 0 60s Acidic ribosomal protein Nitroreductase PF00881.24 KKK16833.1 - 4.5e-16 59.4 0.0 5.5e-16 59.1 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family Ribosomal_L39 PF00832.20 KKK16834.1 - 7.5e-18 63.9 11.8 2.4e-12 46.3 1.5 2.1 2 0 0 2 2 2 2 Ribosomal L39 protein NmrA PF05368.13 KKK16835.1 - 1.6e-14 54.0 0.0 6.7e-14 52.0 0.0 1.8 1 1 1 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.6 KKK16835.1 - 7e-13 48.9 0.1 1.5e-12 47.8 0.0 1.6 2 0 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 KKK16835.1 - 3.4e-06 26.7 0.1 5.1e-06 26.1 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DapB_N PF01113.20 KKK16835.1 - 0.00089 19.4 0.2 0.0023 18.0 0.0 1.8 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus KR PF08659.10 KKK16835.1 - 0.0014 18.6 0.0 0.0023 17.8 0.0 1.4 1 0 0 1 1 1 1 KR domain Semialdhyde_dh PF01118.24 KKK16835.1 - 0.0028 18.1 0.0 0.0054 17.2 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.22 KKK16835.1 - 0.012 16.5 0.1 0.023 15.5 0.1 1.5 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold adh_short PF00106.25 KKK16835.1 - 0.018 14.5 1.0 0.036 13.5 0.7 1.7 1 1 1 2 2 2 0 short chain dehydrogenase RmlD_sub_bind PF04321.17 KKK16835.1 - 0.019 14.1 0.1 0.029 13.5 0.1 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain F420_oxidored PF03807.17 KKK16835.1 - 0.07 13.7 0.9 0.19 12.3 0.9 1.8 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent SepF PF04472.12 KKK16835.1 - 0.089 13.1 0.1 0.19 12.0 0.1 1.5 1 0 0 1 1 1 0 Cell division protein SepF 3HCDH_N PF02737.18 KKK16835.1 - 0.09 12.7 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 KKK16835.1 - 0.098 12.7 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Ldh_1_N PF00056.23 KKK16835.1 - 0.12 12.4 0.6 0.28 11.3 0.6 1.7 1 1 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain ABC_membrane PF00664.23 KKK16836.1 - 4.9e-108 360.9 34.4 4.2e-54 184.1 13.9 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KKK16836.1 - 2e-52 177.4 0.0 1.2e-32 113.3 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KKK16836.1 - 8.9e-09 35.1 1.1 5.5e-06 26.0 0.6 3.5 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 KKK16836.1 - 3.5e-07 30.3 0.0 0.032 14.1 0.0 3.3 3 0 0 3 3 3 2 RsgA GTPase AAA_29 PF13555.6 KKK16836.1 - 4.2e-07 29.6 0.5 0.0055 16.4 0.2 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 KKK16836.1 - 1.4e-06 28.8 2.2 0.079 13.3 0.7 3.3 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 KKK16836.1 - 8.2e-06 26.1 0.8 0.071 13.4 0.0 3.3 2 1 0 2 2 2 2 AAA domain AAA PF00004.29 KKK16836.1 - 8.5e-05 23.0 0.1 1.9 8.9 0.0 3.7 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 KKK16836.1 - 0.0003 20.4 0.0 0.27 10.8 0.1 2.5 2 0 0 2 2 2 2 AAA domain Rad17 PF03215.15 KKK16836.1 - 0.00038 20.4 0.1 0.064 13.2 0.0 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_30 PF13604.6 KKK16836.1 - 0.00066 19.5 2.6 0.9 9.2 0.0 3.3 4 0 0 4 4 4 2 AAA domain AAA_5 PF07728.14 KKK16836.1 - 0.0019 18.2 0.0 3.1 7.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 KKK16836.1 - 0.0021 17.6 0.0 1.3 8.6 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_33 PF13671.6 KKK16836.1 - 0.0023 18.1 0.2 1.8 8.7 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_21 PF13304.6 KKK16836.1 - 0.0024 17.7 0.1 4.1 7.1 0.0 2.9 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_24 PF13479.6 KKK16836.1 - 0.0025 17.5 0.1 0.86 9.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.6 KKK16836.1 - 0.0051 16.6 0.0 2.2 7.9 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 KKK16836.1 - 0.0065 17.0 0.0 5.3 7.6 0.0 2.8 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 KKK16836.1 - 0.0095 16.3 0.1 2.5 8.5 0.0 3.2 3 0 0 3 3 2 1 RNA helicase Zeta_toxin PF06414.12 KKK16836.1 - 0.013 14.7 0.2 4.3 6.6 0.0 2.6 3 0 0 3 3 3 0 Zeta toxin SRP54 PF00448.22 KKK16836.1 - 0.02 14.5 0.3 1.5 8.4 0.0 2.7 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain PRK PF00485.18 KKK16836.1 - 0.026 14.2 0.1 1.4 8.6 0.0 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_23 PF13476.6 KKK16836.1 - 0.043 14.3 4.0 2.5 8.5 0.0 3.3 3 0 0 3 3 2 0 AAA domain DUF87 PF01935.17 KKK16836.1 - 0.044 13.9 0.2 5.1 7.1 0.1 2.6 2 0 0 2 2 2 0 Helicase HerA, central domain G-alpha PF00503.20 KKK16836.1 - 0.049 12.8 0.0 3.1 6.9 0.0 2.4 2 0 0 2 2 2 0 G-protein alpha subunit Cytidylate_kin PF02224.18 KKK16836.1 - 0.05 13.3 0.0 4.1 7.1 0.0 2.7 2 0 0 2 2 2 0 Cytidylate kinase ABC_ATPase PF09818.9 KKK16836.1 - 0.051 12.4 1.1 0.077 11.8 0.1 1.7 2 0 0 2 2 2 0 Predicted ATPase of the ABC class APS_kinase PF01583.20 KKK16836.1 - 0.098 12.5 0.1 2.7 7.9 0.0 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_28 PF13521.6 KKK16836.1 - 0.12 12.6 0.9 4.3 7.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 KKK16836.1 - 0.13 12.7 1.2 12 6.3 0.0 3.3 3 1 1 4 4 3 0 AAA domain MMR_HSR1 PF01926.23 KKK16836.1 - 2.4 8.3 3.8 20 5.3 0.0 3.3 3 0 0 3 3 3 0 50S ribosome-binding GTPase CDC45 PF02724.14 KKK16836.1 - 10 4.3 9.8 0.13 10.6 1.2 1.8 2 0 0 2 2 2 0 CDC45-like protein Glyco_transf_22 PF03901.17 KKK16837.1 - 9.4e-45 153.6 16.0 1.3e-44 153.1 16.0 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family OppC_N PF12911.7 KKK16837.1 - 0.22 11.6 5.9 2.5 8.1 0.4 2.7 1 1 1 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C UBA PF00627.31 KKK16838.1 - 4.5e-25 87.2 2.1 7.1e-13 48.2 0.3 2.5 2 0 0 2 2 2 2 UBA/TS-N domain XPC-binding PF09280.11 KKK16838.1 - 6.9e-24 83.4 15.5 1.2e-23 82.6 15.5 1.4 1 0 0 1 1 1 1 XPC-binding domain ubiquitin PF00240.23 KKK16838.1 - 1.8e-20 72.4 0.3 3.4e-20 71.6 0.3 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 KKK16838.1 - 4.4e-07 29.6 0.5 7.2e-07 29.0 0.5 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.6 KKK16838.1 - 0.00056 20.0 0.0 0.0011 19.0 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA_3 PF09288.10 KKK16838.1 - 0.001 18.8 0.0 0.85 9.5 0.0 2.4 2 0 0 2 2 2 2 Fungal ubiquitin-associated domain Ubiquitin_5 PF18037.1 KKK16838.1 - 0.0039 17.5 0.2 0.0069 16.7 0.2 1.4 1 0 0 1 1 1 1 Ubiquitin-like domain CUE PF02845.16 KKK16838.1 - 0.0097 15.6 0.0 1.3 8.8 0.0 2.6 2 0 0 2 2 2 1 CUE domain DUF2407 PF10302.9 KKK16838.1 - 0.054 14.0 0.0 0.11 13.1 0.0 1.5 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Rap1_C PF11626.8 KKK16838.1 - 0.14 12.3 0.0 1.1 9.4 0.0 2.2 2 0 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain PRCC PF10253.9 KKK16838.1 - 1.7 9.4 10.9 3.2 8.5 0.6 2.2 2 0 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting Skp1 PF01466.19 KKK16839.1 - 2.6e-28 97.9 0.5 4.7e-28 97.0 0.5 1.5 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 KKK16839.1 - 2.5e-25 88.4 0.1 6.6e-25 87.1 0.0 1.7 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain PPR_2 PF13041.6 KKK16840.1 - 7.4e-43 144.5 7.1 8.1e-10 38.7 0.0 13.0 11 3 4 15 15 15 8 PPR repeat family PPR_3 PF13812.6 KKK16840.1 - 4.6e-26 90.7 4.0 0.0027 17.7 0.0 11.0 6 4 5 12 12 12 6 Pentatricopeptide repeat domain PPR PF01535.20 KKK16840.1 - 1e-21 75.6 16.7 0.0011 19.1 0.0 13.1 16 1 0 16 16 15 5 PPR repeat PPR_1 PF12854.7 KKK16840.1 - 5.3e-20 70.8 0.0 1.6e-05 24.5 0.1 8.8 10 0 0 10 10 10 3 PPR repeat PPR_long PF17177.4 KKK16840.1 - 5.3e-19 68.4 14.8 1.4e-09 37.6 0.2 5.6 4 1 1 5 5 5 4 Pentacotripeptide-repeat region of PRORP RPM2 PF08579.11 KKK16840.1 - 2.8e-09 37.4 0.0 0.00025 21.4 0.0 5.5 6 0 0 6 6 6 1 Mitochondrial ribonuclease P subunit (RPM2) TPR_14 PF13428.6 KKK16840.1 - 0.0036 18.0 9.6 39 5.4 0.0 9.1 9 2 2 11 11 9 0 Tetratricopeptide repeat ECSIT PF06239.11 KKK16840.1 - 0.0049 16.0 0.8 0.079 12.1 0.0 2.9 4 0 0 4 4 4 1 Evolutionarily conserved signalling intermediate in Toll pathway MOZART2 PF12926.7 KKK16840.1 - 0.013 15.1 0.1 0.038 13.6 0.1 1.8 1 0 0 1 1 1 0 Mitotic-spindle organizing gamma-tubulin ring associated RPN7 PF10602.9 KKK16840.1 - 0.086 12.5 0.7 20 4.8 0.0 3.6 2 1 1 3 3 3 0 26S proteasome subunit RPN7 GBP_C PF02841.14 KKK16840.1 - 1.9 7.8 5.9 13 5.1 0.0 3.3 3 0 0 3 3 3 0 Guanylate-binding protein, C-terminal domain PNP_phzG_C PF10590.9 KKK16841.1 - 3e-19 68.8 3.9 3e-19 68.8 3.9 2.7 3 0 0 3 3 3 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Putative_PNPOx PF01243.20 KKK16841.1 - 1e-10 41.6 0.0 0.00062 19.9 0.0 2.7 3 0 0 3 3 3 2 Pyridoxamine 5'-phosphate oxidase DUF1206 PF06724.11 KKK16842.1 - 0.027 14.5 0.9 0.059 13.4 0.9 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1206) DUF2749 PF10907.8 KKK16842.1 - 0.22 11.7 3.7 0.18 12.0 0.7 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2749) GHMP_kinases_N PF00288.26 KKK16843.1 - 5.7e-15 55.3 3.5 1.3e-14 54.2 2.4 2.1 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KKK16843.1 - 1.8e-11 44.2 0.0 4.2e-11 43.1 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal PepSY_TM PF03929.16 KKK16843.1 - 0.033 13.9 0.0 0.05 13.3 0.0 1.2 1 0 0 1 1 1 0 PepSY-associated TM region Zn_clus PF00172.18 KKK16844.1 - 5.6e-08 32.8 8.6 1.2e-07 31.7 8.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KKK16844.1 - 0.00017 20.7 0.0 0.00027 20.1 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Alpha-amylase_C PF02806.18 KKK16845.1 - 2.7e-26 91.9 0.0 8.5e-26 90.3 0.0 1.9 2 0 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain CBM_48 PF02922.18 KKK16845.1 - 1.7e-19 70.0 0.1 5e-19 68.4 0.1 1.9 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase PF00128.24 KKK16845.1 - 2.9e-16 60.0 0.0 9.9e-12 45.1 0.1 2.3 1 1 1 2 2 2 2 Alpha amylase, catalytic domain Glyco_hydro_92 PF07971.12 KKK16846.1 - 4.1e-64 217.2 2.0 5.3e-64 216.8 2.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 KKK16846.1 - 4.8e-44 151.0 2.0 7.1e-44 150.5 2.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain TPR_12 PF13424.6 KKK16847.1 - 1e-20 73.8 7.3 7.2e-09 35.8 0.2 5.6 3 2 3 6 6 6 5 Tetratricopeptide repeat TPR_10 PF13374.6 KKK16847.1 - 2.7e-11 42.9 7.2 0.045 13.6 0.1 6.3 6 0 0 6 6 6 5 Tetratricopeptide repeat DUF676 PF05057.14 KKK16847.1 - 3.8e-05 23.3 0.0 0.00016 21.2 0.0 1.8 1 1 1 2 2 2 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 KKK16847.1 - 0.00055 19.7 0.0 0.001 18.8 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein TPR_2 PF07719.17 KKK16847.1 - 0.0089 16.1 1.4 3 8.2 0.2 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat Abhydrolase_6 PF12697.7 KKK16847.1 - 0.012 16.3 0.2 0.028 15.0 0.1 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase family TPR_8 PF13181.6 KKK16847.1 - 0.027 14.7 1.7 3.2 8.2 0.2 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat Hydrolase_4 PF12146.8 KKK16847.1 - 0.031 13.5 0.0 0.082 12.2 0.0 1.7 2 0 0 2 2 2 0 Serine aminopeptidase, S33 TPR_1 PF00515.28 KKK16847.1 - 0.097 12.5 1.3 2.4 8.1 0.2 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Cutinase PF01083.22 KKK16847.1 - 0.1 12.6 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Cutinase TPR_16 PF13432.6 KKK16847.1 - 0.1 13.2 1.5 0.4 11.4 0.1 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Amidase PF01425.21 KKK16848.1 - 1.9e-72 244.7 0.0 8.2e-72 242.6 0.0 2.0 2 1 0 2 2 2 1 Amidase ThiF PF00899.21 KKK16848.1 - 1.8e-56 191.2 0.0 3.5e-56 190.3 0.0 1.4 1 0 0 1 1 1 1 ThiF family Rhodanese PF00581.20 KKK16848.1 - 8.5e-10 39.1 0.0 2.3e-09 37.7 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain DAO PF01266.24 KKK16848.1 - 0.032 13.8 0.0 0.061 12.9 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Shikimate_DH PF01488.20 KKK16848.1 - 0.055 13.5 0.0 0.18 11.9 0.0 1.9 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ApbA PF02558.16 KKK16848.1 - 0.075 12.7 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_7 PF13241.6 KKK16848.1 - 0.091 13.2 0.0 0.3 11.5 0.0 1.8 2 0 0 2 2 2 0 Putative NAD(P)-binding FAD_binding_3 PF01494.19 KKK16848.1 - 0.092 12.0 1.0 0.18 11.0 1.0 1.4 1 0 0 1 1 1 0 FAD binding domain DPBB_1 PF03330.18 KKK16849.1 - 1.4e-07 31.7 0.0 2.4e-07 31.0 0.0 1.4 1 1 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 KKK16849.1 - 0.08 12.8 0.1 0.12 12.2 0.1 1.3 1 0 0 1 1 1 0 Barwin family Myco_arth_vir_N PF09610.10 KKK16849.1 - 0.12 12.5 1.0 0.28 11.3 0.9 1.7 1 1 0 1 1 1 0 Mycoplasma virulence signal region (Myco_arth_vir_N) CBFD_NFYB_HMF PF00808.23 KKK16850.1 - 3.8e-14 52.7 0.1 3.8e-14 52.7 0.1 2.0 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KKK16850.1 - 9.3e-05 22.8 0.1 9.3e-05 22.8 0.1 2.1 2 1 0 2 2 2 1 Core histone H2A/H2B/H3/H4 Pol_alpha_B_N PF08418.10 KKK16850.1 - 0.015 15.3 0.7 0.018 15.0 0.7 1.1 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Peptidase_C14 PF00656.22 KKK16851.1 - 0.00034 20.6 0.0 0.0005 20.1 0.0 1.3 1 0 0 1 1 1 1 Caspase domain Raptor_N PF14538.6 KKK16851.1 - 0.016 15.2 0.0 0.046 13.7 0.0 1.8 2 0 0 2 2 2 0 Raptor N-terminal CASPase like domain She9_MDM33 PF05546.11 KKK16852.1 - 4.6e-88 294.2 8.7 6.6e-88 293.7 8.7 1.2 1 0 0 1 1 1 1 She9 / Mdm33 family SARAF PF06682.12 KKK16852.1 - 0.0033 17.1 0.7 0.0033 17.1 0.7 1.7 2 1 0 2 2 2 1 SOCE-associated regulatory factor of calcium homoeostasis DUF2175 PF09943.9 KKK16852.1 - 0.15 12.4 0.3 0.41 11.0 0.3 1.8 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2175) PsbH PF00737.20 KKK16852.1 - 2 8.2 6.3 0.11 12.3 0.8 1.7 2 0 0 2 2 2 0 Photosystem II 10 kDa phosphoprotein COX4 PF02936.14 KKK16853.1 - 1.9e-46 157.5 0.5 2.5e-46 157.1 0.5 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV DUF1104 PF06518.11 KKK16853.1 - 0.11 12.9 0.6 0.2 12.0 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1104) DUF3007 PF11460.8 KKK16853.1 - 0.19 12.0 0.8 13 6.1 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3007) DUF3106 PF11304.8 KKK16853.1 - 0.24 11.9 7.1 0.076 13.5 4.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3106) Cofilin_ADF PF00241.20 KKK16854.1 - 1.6e-32 111.9 0.0 1.8e-32 111.7 0.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein SpoVR PF04293.13 KKK16854.1 - 0.11 11.2 0.0 0.14 10.8 0.0 1.1 1 0 0 1 1 1 0 SpoVR like protein SH3_9 PF14604.6 KKK16855.1 - 7.9e-05 22.4 0.1 0.00018 21.3 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KKK16855.1 - 0.0023 17.5 0.0 0.0052 16.4 0.0 1.6 1 0 0 1 1 1 1 SH3 domain EphA2_TM PF14575.6 KKK16855.1 - 0.041 14.8 0.0 0.081 13.8 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Adeno_E3_CR2 PF02439.15 KKK16855.1 - 0.18 11.6 0.4 0.39 10.5 0.4 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Voltage_CLC PF00654.20 KKK16856.1 - 1.8e-90 303.7 31.2 1.8e-90 303.7 31.2 1.8 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 KKK16856.1 - 2e-12 47.3 0.0 2.4e-05 24.7 0.0 2.8 2 0 0 2 2 2 2 CBS domain ATPase_gene1 PF09527.10 KKK16856.1 - 1.1 9.5 10.4 5.3 7.3 2.4 3.2 2 0 0 2 2 2 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter Pmp3 PF01679.17 KKK16857.1 - 4.8e-19 68.3 9.4 6.1e-19 68.0 9.4 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator Rieske PF00355.26 KKK16858.1 - 2.4e-11 43.4 0.0 4.6e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain UCR_TM PF02921.14 KKK16858.1 - 5.5e-11 42.8 0.6 1.4e-10 41.5 0.6 1.7 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region ATP-synt_ab PF00006.25 KKK16859.1 - 1.3e-61 208.0 0.0 2.1e-61 207.3 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 KKK16859.1 - 5e-23 81.4 1.3 1.6e-22 79.8 0.8 2.1 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain ATPase PF06745.13 KKK16859.1 - 0.0035 16.7 0.2 0.0061 15.9 0.2 1.4 1 0 0 1 1 1 1 KaiC RsgA_GTPase PF03193.16 KKK16859.1 - 0.016 15.1 0.1 0.039 13.8 0.1 1.6 1 0 0 1 1 1 0 RsgA GTPase T3SS_ATPase_C PF18269.1 KKK16859.1 - 0.016 15.0 0.7 0.068 13.0 0.7 1.9 1 1 0 1 1 1 0 T3SS EscN ATPase C-terminal domain AAA PF00004.29 KKK16859.1 - 0.019 15.4 0.1 0.64 10.4 0.0 2.7 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 KKK16859.1 - 0.019 14.1 0.4 0.11 11.7 0.1 2.0 2 0 0 2 2 2 0 NB-ARC domain ATPase_2 PF01637.18 KKK16859.1 - 0.032 14.1 0.0 0.12 12.3 0.0 1.8 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_19 PF13245.6 KKK16859.1 - 0.044 14.1 0.9 0.48 10.7 0.2 2.3 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KKK16859.1 - 0.052 13.5 0.2 0.13 12.1 0.0 1.7 2 0 0 2 2 2 0 NACHT domain RNA_helicase PF00910.22 KKK16859.1 - 0.1 13.0 0.0 0.21 12.0 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_16 PF13191.6 KKK16859.1 - 0.14 12.6 0.1 0.54 10.6 0.1 2.1 1 1 0 1 1 1 0 AAA ATPase domain GN3L_Grn1 PF08701.11 KKK16860.1 - 2.5e-22 78.7 17.4 2.5e-22 78.7 17.4 2.7 4 0 0 4 4 4 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.23 KKK16860.1 - 6.2e-18 64.9 0.1 6.4e-14 52.0 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KKK16860.1 - 1e-06 28.7 0.0 2.3e-05 24.4 0.0 2.2 1 1 0 1 1 1 1 RsgA GTPase FeoB_N PF02421.18 KKK16860.1 - 1.2e-05 24.9 0.1 9.3e-05 22.0 0.1 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 KKK16860.1 - 5.5e-05 23.3 5.0 0.34 10.9 0.1 4.1 3 2 2 5 5 5 2 Dynamin family GTP_EFTU PF00009.27 KKK16860.1 - 0.00019 21.0 2.5 0.32 10.5 0.0 3.0 3 0 0 3 3 2 2 Elongation factor Tu GTP binding domain AAA_18 PF13238.6 KKK16860.1 - 0.0032 18.0 4.5 0.079 13.5 0.0 2.9 3 0 0 3 3 3 1 AAA domain AIG1 PF04548.16 KKK16860.1 - 0.0089 15.4 0.4 0.61 9.4 0.0 2.8 3 0 0 3 3 3 1 AIG1 family MeaB PF03308.16 KKK16860.1 - 0.028 13.4 0.1 0.028 13.4 0.1 2.0 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB cobW PF02492.19 KKK16860.1 - 0.041 13.5 0.0 0.61 9.7 0.0 2.5 2 1 1 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain Roc PF08477.13 KKK16860.1 - 0.075 13.3 0.0 11 6.3 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase BUD22 PF09073.10 KKK16860.1 - 1.6 8.0 25.1 2.7 7.2 25.1 1.3 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 KKK16860.1 - 3.7 5.6 33.4 5.6 5.0 33.4 1.2 1 0 0 1 1 1 0 Nop14-like family MFS_1 PF07690.16 KKK16875.1 - 7.2e-33 114.0 28.8 7.2e-33 114.0 28.8 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF2070 PF09843.9 KKK16875.1 - 0.5 8.6 21.8 0.015 13.6 6.3 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2070) Synaptobrevin PF00957.21 KKK16876.1 - 6.6e-14 51.5 0.1 1e-13 50.8 0.1 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 KKK16876.1 - 8.7e-10 38.5 0.0 1.7e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 Regulated-SNARE-like domain Herpes_teg_N PF04843.12 KKK16876.1 - 0.1 12.3 0.1 0.56 9.9 0.0 1.9 2 0 0 2 2 2 0 Herpesvirus tegument protein, N-terminal conserved region 3-HAO PF06052.12 KKK16878.1 - 3.4e-54 182.6 0.1 4.3e-54 182.3 0.1 1.1 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.11 KKK16878.1 - 0.0027 17.4 0.0 0.0046 16.6 0.0 1.4 1 0 0 1 1 1 1 Cupin domain fn3_4 PF16794.5 KKK16878.1 - 0.016 15.1 0.1 4 7.4 0.1 2.3 2 0 0 2 2 2 0 Fibronectin-III type domain Nup160 PF11715.8 KKK16879.1 - 0.12 11.0 0.0 0.22 10.1 0.0 1.3 1 0 0 1 1 1 0 Nucleoporin Nup120/160 AA_permease PF00324.21 KKK16881.1 - 3.9e-59 200.5 37.2 3.1e-31 108.5 17.5 1.9 2 0 0 2 2 2 2 Amino acid permease AA_permease_2 PF13520.6 KKK16881.1 - 1.5e-21 76.7 31.9 2.9e-21 75.8 31.9 1.4 1 1 0 1 1 1 1 Amino acid permease PHD PF00628.29 KKK16882.1 - 7.6e-05 22.5 9.7 0.00014 21.7 9.7 1.5 1 0 0 1 1 1 1 PHD-finger SET PF00856.28 KKK16882.1 - 8.9e-05 22.9 1.1 0.00079 19.9 0.2 2.8 2 1 0 2 2 2 1 SET domain Aconitase PF00330.20 KKK16883.1 - 3.6e-161 537.2 0.0 4.5e-161 536.9 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KKK16883.1 - 3.5e-33 114.7 0.0 6.8e-25 87.9 0.0 2.6 1 1 1 2 2 2 2 Aconitase C-terminal domain Aldo_ket_red PF00248.21 KKK16884.1 - 3.1e-68 230.1 0.0 3.9e-68 229.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Glycos_transf_4 PF00953.21 KKK16885.1 - 1.3e-31 109.8 13.7 1.3e-31 109.8 13.7 2.7 3 1 0 3 3 3 1 Glycosyl transferase family 4 DUF2107 PF09880.9 KKK16885.1 - 2.5 8.3 8.6 6.7 6.9 0.7 3.4 3 0 0 3 3 3 0 Predicted membrane protein (DUF2107) WD40 PF00400.32 KKK16886.1 - 2.9e-12 46.9 14.2 0.0029 18.4 1.4 4.9 4 0 0 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKK16886.1 - 0.00012 22.3 0.5 0.073 13.4 0.0 3.5 3 1 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KKK16886.1 - 0.0099 14.9 0.1 4.9 6.0 0.0 2.8 3 0 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KKK16886.1 - 0.088 11.4 2.6 1.7 7.2 0.1 2.2 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Rav1p_C PF12234.8 KKK16886.1 - 0.15 10.4 0.0 0.21 10.0 0.0 1.1 1 0 0 1 1 1 0 RAVE protein 1 C terminal WD40 PF00400.32 KKK16887.1 - 2.1e-16 60.0 13.5 1.4e-05 25.8 0.2 7.1 7 0 0 7 7 7 4 WD domain, G-beta repeat SET PF00856.28 KKK16887.1 - 1.7e-05 25.3 0.0 0.00013 22.4 0.0 2.7 2 1 0 2 2 2 1 SET domain ANAPC4_WD40 PF12894.7 KKK16887.1 - 0.0027 17.9 0.0 0.13 12.6 0.0 2.8 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain zf-MYND PF01753.18 KKK16887.1 - 0.006 16.7 3.7 0.013 15.6 3.7 1.6 1 0 0 1 1 1 1 MYND finger TPR_9 PF13371.6 KKK16887.1 - 0.018 15.2 0.9 0.057 13.6 0.9 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat zf-CRD PF17979.1 KKK16887.1 - 0.11 12.6 1.0 0.24 11.5 1.0 1.4 1 0 0 1 1 1 0 Cysteine rich domain with multizinc binding regions BAR_2 PF10455.9 KKK16888.1 - 3.2e-40 138.1 0.1 4.9e-40 137.5 0.1 1.2 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.18 KKK16888.1 - 7.3e-17 61.8 0.4 8.6e-17 61.6 0.4 1.1 1 0 0 1 1 1 1 BAR domain DUF4111 PF13427.6 KKK16888.1 - 0.0057 16.8 0.1 0.017 15.3 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4111) BAR_3 PF16746.5 KKK16888.1 - 0.0068 16.1 0.1 0.0095 15.7 0.1 1.2 1 0 0 1 1 1 1 BAR domain of APPL family AIB PF15334.6 KKK16888.1 - 0.02 14.2 0.7 0.025 13.9 0.7 1.1 1 0 0 1 1 1 0 Aurora kinase A and ninein interacting protein NOG1_N PF17835.1 KKK16889.1 - 1.1e-49 168.5 0.8 1.7e-49 167.9 0.0 1.8 2 0 0 2 2 2 1 NOG1 N-terminal helical domain NOGCT PF08155.11 KKK16889.1 - 4.3e-28 97.1 4.8 1e-27 95.8 4.8 1.7 1 0 0 1 1 1 1 NOGCT (NUC087) domain NOG1 PF06858.14 KKK16889.1 - 2.5e-26 91.2 0.2 5.7e-26 90.1 0.2 1.7 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.23 KKK16889.1 - 8.5e-16 58.1 0.0 2.2e-15 56.7 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KKK16889.1 - 1e-07 31.6 0.0 2.4e-07 30.4 0.0 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 KKK16889.1 - 0.013 15.5 0.0 8.9 6.3 0.0 2.8 1 1 0 2 2 2 0 Dynamin family RsgA_GTPase PF03193.16 KKK16889.1 - 0.02 14.8 0.1 6.7 6.6 0.1 2.9 2 1 0 2 2 2 0 RsgA GTPase AAA_16 PF13191.6 KKK16889.1 - 0.021 15.2 0.1 0.2 12.0 0.0 2.6 3 0 0 3 3 3 0 AAA ATPase domain AAA_23 PF13476.6 KKK16889.1 - 0.045 14.2 0.1 2.3 8.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain EIF_2_alpha PF07541.12 KKK16889.1 - 0.062 13.4 0.0 0.15 12.1 0.0 1.7 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 2 alpha subunit Sigma54_activ_2 PF14532.6 KKK16889.1 - 0.16 12.1 0.1 0.39 10.8 0.1 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain NAT PF04768.13 KKK16890.1 - 2.6e-52 176.9 0.0 3.2e-51 173.4 0.0 2.3 2 0 0 2 2 2 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase Acetyltransf_1 PF00583.25 KKK16891.1 - 3.8e-14 52.9 0.0 8.4e-14 51.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KKK16891.1 - 9.2e-13 48.3 0.0 1.3e-12 47.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KKK16891.1 - 2.8e-08 34.0 0.0 5.1e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KKK16891.1 - 0.0036 17.4 0.3 0.013 15.6 0.0 2.0 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KKK16891.1 - 0.0096 16.0 0.1 0.021 14.9 0.1 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.10 KKK16891.1 - 0.2 11.6 0.0 0.36 10.8 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein Arv1 PF04161.13 KKK16892.1 - 1.9e-60 204.6 0.0 1.4e-59 201.8 0.0 2.0 1 1 0 1 1 1 1 Arv1-like family ATP_synt_H PF05493.13 KKK16893.1 - 0.00029 21.2 0.2 0.00038 20.9 0.2 1.2 1 0 0 1 1 1 1 ATP synthase subunit H PsbX PF06596.11 KKK16893.1 - 0.02 14.9 0.7 0.02 14.9 0.7 1.5 2 0 0 2 2 2 0 Photosystem II reaction centre X protein (PsbX) DUF1304 PF06993.12 KKK16893.1 - 0.067 13.2 0.1 0.07 13.1 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1304) ApoO PF09769.9 KKK16893.1 - 0.096 12.6 0.0 0.1 12.5 0.0 1.0 1 0 0 1 1 1 0 Apolipoprotein O DUF4748 PF15932.5 KKK16893.1 - 0.22 11.3 0.3 0.27 11.0 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4748) SRR1 PF07985.12 KKK16898.1 - 2.4e-09 37.1 0.2 5.4e-09 36.0 0.0 1.7 2 0 0 2 2 2 1 SRR1 RRP7 PF12923.7 KKK16898.1 - 0.1 12.7 0.8 0.17 12.0 0.2 1.6 2 0 0 2 2 2 0 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain Hydrolase_4 PF12146.8 KKK16922.1 - 7.3e-21 74.5 0.0 1.7e-14 53.7 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KKK16922.1 - 1e-12 48.3 0.1 2.7e-09 37.0 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KKK16922.1 - 3.3e-07 31.1 0.0 5.6e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.12 KKK16922.1 - 3.5e-07 29.2 0.2 0.033 12.9 0.1 3.0 2 1 1 3 3 3 2 Acetyl xylan esterase (AXE1) Peptidase_S9 PF00326.21 KKK16922.1 - 1.3e-05 24.8 0.0 0.16 11.4 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family FSH1 PF03959.13 KKK16922.1 - 2.6e-05 24.0 0.0 9.4e-05 22.2 0.0 1.8 2 1 0 2 2 2 1 Serine hydrolase (FSH1) BAAT_C PF08840.11 KKK16922.1 - 0.00018 21.5 0.0 0.016 15.2 0.0 2.3 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_3 PF07859.13 KKK16922.1 - 0.00069 19.5 0.0 0.0012 18.8 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.18 KKK16922.1 - 0.00087 18.9 0.0 0.16 11.5 0.0 2.2 2 0 0 2 2 2 1 Dienelactone hydrolase family Peptidase_S15 PF02129.18 KKK16922.1 - 0.0059 16.2 0.0 1.6 8.2 0.0 2.2 2 0 0 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) Esterase PF00756.20 KKK16922.1 - 0.0088 15.7 0.0 0.018 14.7 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Abhydrolase_2 PF02230.16 KKK16922.1 - 0.011 15.6 0.0 0.89 9.3 0.0 2.3 1 1 1 2 2 2 0 Phospholipase/Carboxylesterase DUF818 PF05677.12 KKK16922.1 - 0.024 13.6 0.0 0.035 13.1 0.0 1.1 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) PGAP1 PF07819.13 KKK16922.1 - 0.024 14.4 0.2 0.39 10.4 0.1 2.2 1 1 0 1 1 1 0 PGAP1-like protein LIDHydrolase PF10230.9 KKK16922.1 - 0.028 14.0 0.0 0.47 10.0 0.0 2.0 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase Lipase_3 PF01764.25 KKK16922.1 - 0.061 13.2 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DUF2974 PF11187.8 KKK16922.1 - 0.08 12.5 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Abhydrolase_5 PF12695.7 KKK16922.1 - 0.15 11.9 0.0 0.34 10.7 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Proteasome PF00227.26 KKK16923.1 - 2.3e-46 157.7 0.1 2.7e-46 157.5 0.1 1.0 1 0 0 1 1 1 1 Proteasome subunit Cyclin PF08613.11 KKK16924.1 - 6.2e-38 130.7 11.2 3.6e-24 86.0 0.1 3.4 3 1 0 3 3 3 2 Cyclin Orthopox_A5L PF06193.11 KKK16924.1 - 4.1 6.8 10.3 0.12 11.7 2.3 2.4 3 0 0 3 3 3 0 Orthopoxvirus A5L protein-like RhoGEF PF00621.20 KKK16925.1 - 8.9e-35 120.6 0.0 1.9e-34 119.5 0.0 1.6 1 0 0 1 1 1 1 RhoGEF domain BAR PF03114.18 KKK16925.1 - 1.8e-11 44.1 1.0 4.9e-11 42.7 1.0 1.7 1 0 0 1 1 1 1 BAR domain Peptidase_C48 PF02902.19 KKK16925.1 - 0.0014 18.5 0.0 0.0043 16.9 0.0 1.7 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain GATase_5 PF13507.6 KKK16927.1 - 1.1e-101 339.3 0.0 1.6e-101 338.8 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.22 KKK16927.1 - 1.5e-37 129.1 0.6 2.7e-24 86.1 0.3 2.7 3 0 0 3 3 3 2 AIR synthase related protein, C-terminal domain FGAR-AT_N PF18076.1 KKK16927.1 - 2.5e-33 114.5 0.0 4.6e-33 113.6 0.0 1.5 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase N-terminal FGAR-AT_linker PF18072.1 KKK16927.1 - 1.7e-13 50.9 0.0 4e-13 49.7 0.0 1.7 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase linker domain Fungal_trans PF04082.18 KKK16928.1 - 3.6e-06 26.2 0.0 8e-06 25.1 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK16928.1 - 3.7e-06 27.0 11.8 6.4e-06 26.2 11.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 KKK16929.1 - 4.9e-43 147.4 32.6 4.9e-43 147.4 32.6 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KKK16929.1 - 9.3e-11 41.2 2.7 9.3e-11 41.2 2.7 2.6 3 1 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 KKK16929.1 - 2.6e-09 36.1 2.1 4.9e-09 35.2 2.1 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Asp PF00026.23 KKK16930.1 - 5.8e-46 157.4 1.6 8.7e-46 156.8 1.6 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.6 KKK16930.1 - 1.8e-05 25.3 0.5 4.4 8.0 0.0 3.7 3 0 0 3 3 3 3 Aspartyl protease TAXi_N PF14543.6 KKK16930.1 - 7.4e-05 23.1 0.7 0.00028 21.1 0.0 2.3 3 0 0 3 3 3 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 KKK16930.1 - 0.0041 16.9 0.0 0.067 13.0 0.0 2.3 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal MatB PF16449.5 KKK16930.1 - 0.0041 16.9 0.1 0.014 15.2 0.1 1.9 1 1 1 2 2 2 1 Fimbrillin MatB gag-asp_proteas PF13975.6 KKK16930.1 - 0.062 13.9 0.4 14 6.3 0.0 3.5 3 0 0 3 3 3 0 gag-polyprotein putative aspartyl protease Glyco_transf_15 PF01793.16 KKK16931.1 - 1.5e-112 376.1 7.5 1.8e-112 375.8 7.5 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase COX5A PF02284.16 KKK16932.1 - 3.5e-30 104.0 0.0 4e-30 103.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va GCP_N_terminal PF17681.1 KKK16933.1 - 5.2e-42 144.5 6.4 3.4e-41 141.9 0.9 2.4 2 0 0 2 2 2 2 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 KKK16933.1 - 8.9e-29 100.9 0.8 1.9e-28 99.8 0.8 1.6 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP5-Mod21 PF14609.6 KKK16933.1 - 1.4e-07 30.3 0.1 4.7e-07 28.6 0.0 1.9 2 0 0 2 2 2 1 gamma-Tubulin ring complex non-core subunit mod21 Sigma70_ner PF04546.13 KKK16933.1 - 0.00037 20.4 1.8 0.00083 19.3 1.8 1.5 1 0 0 1 1 1 1 Sigma-70, non-essential region CENP-B_dimeris PF09026.10 KKK16933.1 - 0.01 16.2 10.6 0.029 14.8 10.6 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Pox_Ag35 PF03286.14 KKK16933.1 - 0.24 11.2 4.2 0.55 10.0 4.2 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein RXT2_N PF08595.11 KKK16933.1 - 0.33 11.0 5.9 0.71 9.9 5.9 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal RNA_pol_3_Rpc31 PF11705.8 KKK16933.1 - 0.37 11.0 11.2 4.5 7.4 11.1 2.2 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 NOA36 PF06524.12 KKK16933.1 - 0.45 9.8 9.2 0.69 9.2 9.2 1.2 1 0 0 1 1 1 0 NOA36 protein Cwf_Cwc_15 PF04889.12 KKK16933.1 - 0.54 9.9 11.4 0.023 14.4 5.6 1.6 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein FAM176 PF14851.6 KKK16933.1 - 2.8 7.6 4.9 6.6 6.4 4.9 1.6 1 0 0 1 1 1 0 FAM176 family GCIP PF13324.6 KKK16933.1 - 3.2 7.3 5.7 12 5.4 1.9 2.5 2 0 0 2 2 2 0 Grap2 and cyclin-D-interacting Lon_C PF05362.13 KKK16950.1 - 1.3e-64 217.5 0.0 2.2e-64 216.8 0.0 1.4 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 KKK16950.1 - 2.6e-33 115.7 0.0 6.6e-33 114.3 0.0 1.7 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 KKK16950.1 - 8.5e-22 78.0 0.0 2e-21 76.8 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KKK16950.1 - 2.4e-07 30.8 0.0 4.5e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.6 KKK16950.1 - 3.3e-07 30.2 0.0 1.2e-06 28.4 0.0 2.0 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_2 PF07724.14 KKK16950.1 - 2.9e-06 27.5 0.0 8.7e-06 26.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 KKK16950.1 - 7.9e-06 26.2 0.1 9.6e-05 22.7 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_PrkA PF08298.11 KKK16950.1 - 3.6e-05 22.9 0.2 8e-05 21.7 0.0 1.6 2 0 0 2 2 2 1 PrkA AAA domain AAA_16 PF13191.6 KKK16950.1 - 0.00012 22.5 1.1 0.00063 20.2 0.0 2.5 2 1 1 3 3 2 1 AAA ATPase domain RuvB_N PF05496.12 KKK16950.1 - 0.00021 21.1 0.0 0.00068 19.4 0.0 1.8 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 KKK16950.1 - 0.00093 19.7 1.0 0.0038 17.8 0.0 2.5 3 0 0 3 3 2 1 AAA domain AAA_14 PF13173.6 KKK16950.1 - 0.0046 17.0 0.0 0.012 15.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KKK16950.1 - 0.016 15.0 0.0 0.037 13.8 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_30 PF13604.6 KKK16950.1 - 0.022 14.5 0.0 0.052 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 KKK16950.1 - 0.023 14.6 0.1 0.35 10.8 0.0 2.7 2 1 1 3 3 3 0 NTPase DUF4276 PF14103.6 KKK16950.1 - 0.024 14.8 0.7 0.063 13.5 0.2 1.9 2 0 0 2 2 1 0 Domain of unknown function (DUF4276) RNA_helicase PF00910.22 KKK16950.1 - 0.037 14.4 0.0 0.13 12.6 0.0 2.0 1 0 0 1 1 1 0 RNA helicase RsgA_GTPase PF03193.16 KKK16950.1 - 0.054 13.4 0.0 0.16 11.8 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase MCM PF00493.23 KKK16950.1 - 0.093 11.8 0.0 0.19 10.8 0.0 1.5 1 0 0 1 1 1 0 MCM P-loop domain DNTTIP1_dimer PF18192.1 KKK16950.1 - 0.096 13.1 1.1 11 6.5 0.1 3.3 2 2 0 2 2 2 0 DNTTIP1 dimerisation domain AAA_7 PF12775.7 KKK16950.1 - 0.1 12.1 0.0 0.23 10.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region ABC_tran PF00005.27 KKK16950.1 - 0.15 12.6 1.6 0.33 11.5 0.1 2.3 2 0 0 2 2 2 0 ABC transporter TsaE PF02367.17 KKK16950.1 - 0.15 12.1 0.0 0.33 10.9 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 KKK16950.1 - 0.18 11.7 0.0 0.66 9.9 0.0 2.0 1 1 0 1 1 1 0 NACHT domain BRO1 PF03097.18 KKK16951.1 - 1.2e-125 419.4 0.1 2.2e-125 418.5 0.1 1.5 1 0 0 1 1 1 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 KKK16951.1 - 3.2e-65 220.3 12.3 1.5e-62 211.6 12.3 2.5 1 1 0 1 1 1 1 ALIX V-shaped domain binding to HIV DnaJ_C PF01556.18 KKK16951.1 - 1.3e-33 116.2 0.0 2.1e-33 115.5 0.0 1.4 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KKK16951.1 - 2.8e-22 78.6 0.6 8.1e-22 77.1 0.6 1.9 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KKK16951.1 - 2.5e-09 37.4 20.2 5.4e-09 36.3 20.2 1.6 1 0 0 1 1 1 1 DnaJ central domain Cytochrome_C7 PF14522.6 KKK16951.1 - 0.39 10.7 4.1 7.6 6.6 0.3 2.8 2 0 0 2 2 2 0 Cytochrome c7 and related cytochrome c Anti-TRAP PF15777.5 KKK16951.1 - 1.8 8.6 16.2 0.14 12.1 2.9 3.6 3 1 1 4 4 4 0 Tryptophan RNA-binding attenuator protein inhibitory protein Pkinase PF00069.25 KKK16952.1 - 3.1e-10 39.9 0.0 4e-09 36.2 0.0 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK16952.1 - 2.6e-09 36.8 0.0 2.7e-08 33.4 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase cobW PF02492.19 KKK16953.1 - 6.9e-49 165.8 0.1 8.9e-49 165.5 0.1 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 KKK16953.1 - 2.9e-05 23.9 0.0 5.7e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain RsgA_GTPase PF03193.16 KKK16953.1 - 0.00015 21.7 0.0 0.54 10.2 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 KKK16953.1 - 0.0016 18.9 0.0 0.0049 17.3 0.0 1.8 2 0 0 2 2 1 1 AAA ATPase domain Septin PF00735.18 KKK16953.1 - 0.005 16.2 0.2 0.98 8.6 0.0 2.1 2 0 0 2 2 2 2 Septin MMR_HSR1 PF01926.23 KKK16953.1 - 0.011 15.9 0.0 0.021 14.9 0.0 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_22 PF13401.6 KKK16953.1 - 0.013 15.8 0.3 0.23 11.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain MeaB PF03308.16 KKK16953.1 - 0.018 14.0 0.3 2.2 7.2 0.0 2.7 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_23 PF13476.6 KKK16953.1 - 0.042 14.4 0.0 0.07 13.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 KKK16953.1 - 0.048 13.6 0.0 0.072 13.0 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea T2SSE PF00437.20 KKK16953.1 - 0.048 12.7 0.0 0.098 11.7 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein ABC_tran PF00005.27 KKK16953.1 - 0.048 14.2 0.4 0.37 11.3 0.0 2.4 3 0 0 3 3 3 0 ABC transporter AAA_29 PF13555.6 KKK16953.1 - 0.049 13.4 0.1 0.15 11.8 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain GTP_EFTU PF00009.27 KKK16953.1 - 0.055 13.0 0.1 5.7 6.4 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_18 PF13238.6 KKK16953.1 - 0.1 13.1 0.3 0.24 12.0 0.3 1.8 1 1 0 1 1 1 0 AAA domain TsaE PF02367.17 KKK16953.1 - 0.11 12.6 0.0 0.26 11.3 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zeta_toxin PF06414.12 KKK16953.1 - 0.12 11.6 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin DUF2577 PF10844.8 KKK16953.1 - 0.13 12.5 0.0 0.27 11.5 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2577) Mob1_phocein PF03637.17 KKK16954.1 - 2e-26 93.0 0.3 3.6e-26 92.2 0.0 1.5 2 0 0 2 2 2 1 Mob1/phocein family Diphthamide_syn PF01866.17 KKK16955.1 - 2e-88 296.7 0.0 2.5e-88 296.4 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein FAM176 PF14851.6 KKK16955.1 - 0.25 11.0 2.0 0.59 9.8 2.0 1.6 1 0 0 1 1 1 0 FAM176 family PAXIP1_C PF15364.6 KKK16955.1 - 0.25 11.7 5.4 0.52 10.6 5.4 1.5 1 0 0 1 1 1 0 PAXIP1-associated-protein-1 C term PTIP binding protein DUF4746 PF15928.5 KKK16955.1 - 0.75 9.2 5.6 1.3 8.3 5.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DNA_pol_phi PF04931.13 KKK16955.1 - 4 5.4 7.1 7 4.6 7.1 1.3 1 0 0 1 1 1 0 DNA polymerase phi TFIIE-A_C PF11521.8 KKK16955.1 - 5.5 7.4 13.5 14 6.1 0.0 2.8 3 0 0 3 3 3 0 C-terminal general transcription factor TFIIE alpha NOA36 PF06524.12 KKK16955.1 - 7.5 5.8 7.2 12 5.1 7.2 1.2 1 0 0 1 1 1 0 NOA36 protein CS PF04969.16 KKK16957.1 - 1.4e-18 67.7 0.3 2.6e-18 66.8 0.0 1.6 2 0 0 2 2 2 1 CS domain Cutinase PF01083.22 KKK16958.1 - 9.2e-49 165.8 0.0 1e-48 165.6 0.0 1.0 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 KKK16958.1 - 0.00018 21.1 0.0 0.00029 20.5 0.0 1.3 1 0 0 1 1 1 1 PE-PPE domain VirJ PF06057.11 KKK16958.1 - 0.0086 16.0 0.0 0.013 15.4 0.0 1.2 1 0 0 1 1 1 1 Bacterial virulence protein (VirJ) DUF2974 PF11187.8 KKK16958.1 - 0.083 12.4 0.0 0.1 12.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Zn_clus PF00172.18 KKK16959.1 - 4.7e-10 39.4 10.1 8.3e-10 38.6 10.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Clusterin PF01093.17 KKK16959.1 - 1.1 8.2 3.9 1.4 7.9 3.9 1.1 1 0 0 1 1 1 0 Clusterin DUF1771 PF08590.10 KKK16960.1 - 2.1e-08 34.4 8.8 3.9e-08 33.6 8.8 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) CUE PF02845.16 KKK16960.1 - 2e-07 30.6 0.0 4.6e-05 23.0 0.0 3.3 3 0 0 3 3 3 1 CUE domain Smr PF01713.21 KKK16960.1 - 0.0011 19.2 0.1 0.0034 17.7 0.1 1.8 2 0 0 2 2 2 1 Smr domain DMA PF03474.14 KKK16960.1 - 0.029 14.0 0.0 0.085 12.5 0.0 1.8 1 0 0 1 1 1 0 DMRTA motif zf-C2H2_2 PF12756.7 KKK16961.1 - 4e-39 133.0 10.9 8.6e-32 109.5 2.7 3.4 3 0 0 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 KKK16961.1 - 1.6e-07 31.4 6.1 1.6e-07 31.4 6.1 4.1 4 1 0 4 4 4 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KKK16961.1 - 1.3e-05 25.5 4.7 1.3e-05 25.5 4.7 3.1 3 0 0 3 3 3 1 Zinc-finger of C2H2 type DUF2024 PF09630.10 KKK16961.1 - 0.003 17.4 3.9 0.57 10.1 0.3 2.7 2 0 0 2 2 2 2 Domain of unknown function (DUF2024) zf-LYAR PF08790.11 KKK16961.1 - 0.0031 17.4 4.4 0.0067 16.3 0.7 2.8 2 0 0 2 2 2 1 LYAR-type C2HC zinc finger zf-C2H2 PF00096.26 KKK16961.1 - 0.023 15.2 18.9 0.063 13.8 0.4 4.4 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KKK16961.1 - 0.043 14.7 12.9 0.65 11.0 0.6 4.4 4 0 0 4 4 4 0 C2H2-type zinc finger Cytochrome_C554 PF13435.6 KKK16961.1 - 0.052 14.5 8.3 5.2 8.1 0.3 3.8 3 0 0 3 3 3 0 Cytochrome c554 and c-prime DUF21 PF01595.20 KKK16962.1 - 7.1e-31 107.3 0.0 1.2e-30 106.5 0.0 1.3 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 KKK16962.1 - 1.6e-06 28.4 1.2 0.031 14.7 0.0 3.6 3 0 0 3 3 3 2 CBS domain His_Phos_1 PF00300.22 KKK16963.1 - 2.7e-15 56.6 0.0 1.3e-14 54.3 0.0 1.9 1 1 1 2 2 2 1 Histidine phosphatase superfamily (branch 1) DAO PF01266.24 KKK16963.1 - 0.061 12.9 0.3 0.09 12.3 0.3 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase DUF1248 PF06852.12 KKK16963.1 - 0.12 11.8 0.1 0.24 10.8 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1248) HECT PF00632.25 KKK16964.1 - 3.2e-71 240.3 0.0 1.5e-70 238.2 0.0 1.9 1 1 0 1 1 1 1 HECT-domain (ubiquitin-transferase) AZUL PF16558.5 KKK16964.1 - 2.2e-21 75.8 2.2 5.4e-21 74.6 2.2 1.7 1 0 0 1 1 1 1 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A Rubella_E2 PF05749.11 KKK16965.1 - 0.66 9.4 6.1 1.2 8.5 6.1 1.4 1 0 0 1 1 1 0 Rubella membrane glycoprotein E2 betaPIX_CC PF16523.5 KKK16965.1 - 4 7.3 13.5 16 5.4 12.1 2.1 1 1 1 2 2 2 0 betaPIX coiled coil TraQ PF09679.10 KKK16966.1 - 0.04 13.8 0.0 0.12 12.3 0.0 1.8 2 0 0 2 2 2 0 Type-F conjugative transfer system pilin chaperone (TraQ) Peptidase_M20 PF01546.28 KKK16967.1 - 2.7e-24 86.0 0.0 5.5e-23 81.7 0.0 2.4 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 WD40 PF00400.32 KKK16967.1 - 2.6e-06 28.1 12.5 0.41 11.6 0.3 6.3 6 0 0 6 6 6 2 WD domain, G-beta repeat M20_dimer PF07687.14 KKK16967.1 - 8.1e-05 22.5 0.0 0.00017 21.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KKK16967.1 - 0.00015 21.5 0.0 0.00066 19.4 0.0 2.0 2 0 0 2 2 2 1 Peptidase family M28 ANAPC4_WD40 PF12894.7 KKK16967.1 - 0.015 15.5 0.0 6.1 7.2 0.0 3.3 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 KKK16967.1 - 0.017 15.6 0.3 10 6.7 0.0 4.1 3 0 0 3 3 3 0 PQQ-like domain SpdB PF05122.13 KKK16967.1 - 0.17 12.0 1.9 0.18 11.9 0.1 2.0 2 0 0 2 2 2 0 Mobile element transfer protein DUF747 PF05346.11 KKK16968.1 - 2e-118 395.5 4.4 2e-118 395.5 4.4 1.8 2 0 0 2 2 2 1 Eukaryotic membrane protein family KCH PF16944.5 KKK16968.1 - 2e-98 329.2 6.0 2.4e-98 328.9 3.6 2.1 2 0 0 2 2 2 1 Fungal potassium channel Shisa PF13908.6 KKK16968.1 - 0.97 9.6 6.5 0.24 11.6 0.2 3.2 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator DUF4834 PF16118.5 KKK16968.1 - 1.5 9.8 3.0 8.2 7.5 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) FMO-like PF00743.19 KKK16969.1 - 4.3e-13 48.6 2.5 1.5e-10 40.2 0.2 3.0 1 1 1 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KKK16969.1 - 9.8e-11 41.4 0.0 7.2e-05 22.2 0.0 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KKK16969.1 - 1.1e-08 35.2 0.0 2.8e-08 33.8 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KKK16969.1 - 1.1e-08 34.7 0.0 7.3e-07 28.7 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KKK16969.1 - 9.4e-07 28.7 0.0 0.00013 21.6 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase K_oxygenase PF13434.6 KKK16969.1 - 4.2e-06 26.2 0.1 0.0019 17.4 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 KKK16969.1 - 0.0014 17.9 0.1 0.0026 17.0 0.1 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.6 KKK16969.1 - 0.0028 17.6 0.1 0.012 15.5 0.0 2.1 3 0 0 3 3 3 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 KKK16969.1 - 0.016 14.3 0.1 0.024 13.7 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain Shikimate_DH PF01488.20 KKK16969.1 - 0.057 13.5 0.0 20 5.2 0.1 3.0 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase Bcr-Abl_Oligo PF09036.10 KKK16970.1 - 0.019 15.0 2.7 2.4 8.2 0.0 3.0 2 0 0 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain POPLD PF08170.12 KKK16970.1 - 0.03 14.7 0.3 3.3 8.1 0.1 3.1 2 0 0 2 2 2 0 POPLD (NUC188) domain Pox_A_type_inc PF04508.12 KKK16970.1 - 0.041 13.7 6.8 0.79 9.7 0.0 4.9 5 0 0 5 5 5 0 Viral A-type inclusion protein repeat SBP_bac_11 PF13531.6 KKK16970.1 - 0.77 9.5 5.5 0.23 11.2 0.5 2.3 2 1 0 2 2 2 0 Bacterial extracellular solute-binding protein PhageMin_Tail PF10145.9 KKK16970.1 - 1.5 8.6 5.8 1.3 8.8 0.9 2.3 2 0 0 2 2 2 0 Phage-related minor tail protein Corona_S2 PF01601.16 KKK16970.1 - 2 6.8 9.0 1.6 7.1 5.5 2.0 1 1 0 2 2 2 0 Coronavirus S2 glycoprotein MFS_1 PF07690.16 KKK16974.1 - 7.3e-36 123.8 22.8 1.1e-35 123.3 22.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily PIG-P PF08510.12 KKK16975.1 - 3.8 7.5 9.6 2.3 8.2 2.4 2.7 2 0 0 2 2 2 0 PIG-P DHHC PF01529.20 KKK16975.1 - 7.2 6.7 7.8 14 5.8 7.8 1.4 1 0 0 1 1 1 0 DHHC palmitoyltransferase SSP160 PF06933.11 KKK16975.1 - 9.2 4.3 8.6 13 3.8 8.6 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 ELO PF01151.18 KKK16976.1 - 1.4e-85 286.8 5.2 1.7e-85 286.6 5.2 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family Glyco_hydro_35 PF01301.19 KKK16977.1 - 1.3e-79 268.1 2.6 1.3e-79 268.1 2.6 1.9 2 1 0 2 2 2 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.6 KKK16977.1 - 7.6e-63 210.2 8.7 8.5e-35 119.8 0.1 3.3 3 0 0 3 3 3 2 Beta-galactosidase jelly roll domain BetaGal_dom2 PF10435.9 KKK16977.1 - 1.7e-62 210.4 0.3 3.5e-62 209.4 0.3 1.5 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom3 PF13363.6 KKK16977.1 - 1.3e-27 95.1 0.1 2.9e-27 94.0 0.1 1.6 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 SKG6 PF08693.10 KKK16978.1 - 2.9e-05 23.4 3.7 2.9e-05 23.4 3.7 1.9 2 0 0 2 2 1 1 Transmembrane alpha-helix domain DUF4448 PF14610.6 KKK16978.1 - 8.9e-05 22.3 0.0 0.00014 21.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) DUF3188 PF11384.8 KKK16978.1 - 0.0025 17.5 0.7 0.0044 16.7 0.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3188) EphA2_TM PF14575.6 KKK16978.1 - 0.01 16.7 0.0 0.05 14.5 0.0 2.0 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF2370 PF10176.9 KKK16978.1 - 0.013 15.1 2.7 0.018 14.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2370) AJAP1_PANP_C PF15298.6 KKK16978.1 - 0.017 15.4 5.7 0.028 14.6 5.7 1.3 1 0 0 1 1 1 0 AJAP1/PANP C-terminus Menin PF05053.13 KKK16978.1 - 0.02 13.3 2.4 0.027 12.9 2.4 1.3 1 0 0 1 1 1 0 Menin TMEM154 PF15102.6 KKK16978.1 - 0.02 14.8 7.4 0.098 12.6 7.4 2.0 1 1 0 1 1 1 0 TMEM154 protein family Adeno_E3_CR2 PF02439.15 KKK16978.1 - 0.042 13.6 0.1 0.072 12.9 0.1 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 RIFIN PF02009.16 KKK16978.1 - 0.064 13.1 0.0 0.086 12.7 0.0 1.1 1 0 0 1 1 1 0 Rifin TMEM51 PF15345.6 KKK16978.1 - 0.53 10.1 0.0 0.53 10.1 0.0 2.3 1 1 0 2 2 2 0 Transmembrane protein 51 Orf78 PF06024.12 KKK16978.1 - 2.3 8.6 9.9 1.3e+02 2.9 9.9 2.3 1 1 0 1 1 1 0 Orf78 (ac78) AIM3 PF17096.5 KKK16979.1 - 0.00077 20.3 0.1 0.00077 20.3 0.1 5.3 5 1 0 5 5 5 2 Altered inheritance of mitochondria protein 3 TAF4 PF05236.14 KKK16980.1 - 1.7e-31 110.0 0.7 3.2e-23 82.9 1.5 2.1 2 0 0 2 2 2 2 Transcription initiation factor TFIID component TAF4 family CPSF73-100_C PF11718.8 KKK16981.1 - 1.3e-83 279.8 0.2 1.3e-83 279.8 0.2 2.6 3 0 0 3 3 3 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term TruD PF01142.18 KKK16981.1 - 2.5e-56 191.3 0.0 1.1e-52 179.3 0.0 2.8 2 2 0 2 2 2 2 tRNA pseudouridine synthase D (TruD) Beta-Casp PF10996.8 KKK16981.1 - 1.1e-29 103.0 0.0 6.6e-29 100.4 0.0 2.3 2 0 0 2 2 2 1 Beta-Casp domain Lactamase_B PF00753.27 KKK16981.1 - 7.6e-21 75.0 0.2 1.6e-20 74.0 0.2 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_6 PF16661.5 KKK16981.1 - 1.6e-15 57.1 0.0 2.8e-15 56.3 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain RMMBL PF07521.12 KKK16981.1 - 2.9e-11 43.1 0.0 6.6e-11 42.0 0.0 1.6 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_2 PF12706.7 KKK16981.1 - 8.5e-05 22.2 0.2 0.00022 20.8 0.2 1.7 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KKK16981.1 - 0.00061 19.7 0.1 0.002 18.0 0.1 1.8 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Pkinase PF00069.25 KKK16982.1 - 2.6e-47 161.4 0.0 1.5e-46 158.9 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK16982.1 - 1.3e-19 70.6 0.0 1.4e-18 67.1 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase GGACT PF06094.12 KKK16983.1 - 0.00016 22.3 0.0 0.00021 21.9 0.0 1.2 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like AIG2_2 PF13772.6 KKK16983.1 - 0.00029 21.2 0.0 0.00052 20.4 0.0 1.4 1 0 0 1 1 1 1 AIG2-like family TGF_beta_GS PF08515.12 KKK16983.1 - 0.17 11.4 2.8 0.38 10.3 2.8 1.5 1 0 0 1 1 1 0 Transforming growth factor beta type I GS-motif Glyco_hydro_47 PF01532.20 KKK16984.1 - 5.6e-119 398.0 0.0 7.2e-119 397.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Pribosyltran PF00156.27 KKK16986.1 - 1.6e-14 53.7 0.0 2.2e-14 53.3 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 KKK16986.1 - 0.0055 16.2 0.0 0.0078 15.7 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase TRAPP PF04051.16 KKK16987.1 - 5.2e-37 126.8 0.0 6.1e-37 126.6 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component DUF4250 PF14056.6 KKK16987.1 - 0.057 13.4 0.1 0.13 12.2 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4250) WD40 PF00400.32 KKK16989.1 - 4.3e-44 147.6 3.4 4.2e-07 30.5 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKK16989.1 - 2.8e-10 40.3 0.1 0.11 12.8 0.0 5.2 2 1 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KKK16989.1 - 0.00023 20.6 0.0 0.75 9.1 0.0 3.7 2 1 2 4 4 4 1 WD40-like domain Nucleoporin_N PF08801.11 KKK16989.1 - 0.00089 18.1 1.6 1.1 7.9 0.1 3.4 1 1 2 3 3 3 2 Nup133 N terminal like Nup160 PF11715.8 KKK16989.1 - 0.012 14.3 0.2 8.6 4.9 0.0 3.6 2 1 2 4 4 4 0 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KKK16989.1 - 0.088 11.7 0.0 4 6.3 0.0 2.5 2 1 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_2 PF13360.6 KKK16989.1 - 0.11 12.0 1.4 12 5.4 0.0 3.1 1 1 1 3 3 3 0 PQQ-like domain Not3 PF04065.15 KKK16995.1 - 1.7e-88 296.0 18.4 2.4e-88 295.4 18.4 1.2 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.18 KKK16995.1 - 1.6e-45 154.4 12.3 3.4e-45 153.3 12.3 1.6 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family GbpC PF08363.10 KKK16995.1 - 0.03 13.8 0.2 0.18 11.2 0.0 2.1 1 1 1 2 2 2 0 Glucan-binding protein C Cep57_MT_bd PF06657.13 KKK16995.1 - 0.11 12.9 5.1 1.3 9.5 0.2 2.7 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 DUF1192 PF06698.11 KKK16995.1 - 0.12 12.4 2.2 0.27 11.3 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) DUF2373 PF10180.9 KKK16995.1 - 0.15 11.9 6.3 0.038 13.8 2.7 1.9 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2373) Snapin_Pallidin PF14712.6 KKK16995.1 - 0.31 11.5 5.2 0.9 10.0 1.0 2.5 2 0 0 2 2 2 0 Snapin/Pallidin GIT_CC PF16559.5 KKK16995.1 - 0.36 10.7 2.2 3.6 7.5 0.4 2.5 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor RPW8 PF05659.11 KKK16995.1 - 1.6 8.4 9.3 0.19 11.4 4.2 2.1 2 0 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Swi5 PF07061.11 KKK16995.1 - 3.8 7.7 8.7 4.2 7.5 1.1 3.2 2 1 1 3 3 3 0 Swi5 Syntaxin_2 PF14523.6 KKK16995.1 - 7.6 7.0 12.5 0.046 14.1 1.9 2.7 3 0 0 3 3 3 0 Syntaxin-like protein DUF1690 PF07956.11 KKK16995.1 - 7.8 6.9 12.9 5.6 7.4 6.2 2.4 1 1 1 2 2 2 0 Protein of Unknown function (DUF1690) Tyr_Deacylase PF02580.16 KKK16996.1 - 5.2e-50 169.7 0.0 7.1e-50 169.3 0.0 1.1 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase Pro_isomerase PF00160.21 KKK16997.1 - 4.3e-50 170.1 0.4 8.3e-50 169.1 0.4 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_2 PF07719.17 KKK16997.1 - 4e-07 29.6 4.6 3.8e-05 23.5 0.1 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 KKK16997.1 - 1.9e-06 27.4 4.6 1.2e-05 24.9 0.1 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 KKK16997.1 - 0.0001 22.5 3.3 0.00019 21.7 1.9 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 KKK16997.1 - 0.00036 20.5 3.3 0.015 15.5 0.1 3.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_9 PF13371.6 KKK16997.1 - 0.004 17.3 1.0 0.064 13.4 0.7 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 KKK16997.1 - 0.05 14.5 2.0 0.12 13.3 0.9 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 KKK16997.1 - 0.061 13.0 4.2 3.3 7.5 0.3 3.3 2 1 1 3 3 3 0 TPR repeat Ribonuclease PF00545.20 KKK16997.1 - 0.064 14.0 0.0 0.14 13.0 0.0 1.5 1 0 0 1 1 1 0 ribonuclease TPR_16 PF13432.6 KKK16997.1 - 0.083 13.6 3.4 1 10.1 2.9 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 KKK16997.1 - 0.2 12.4 0.9 2 9.2 0.2 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 KKK16997.1 - 0.27 11.8 2.8 0.65 10.6 2.8 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat MIF4G PF02854.19 KKK16999.1 - 3.4e-24 85.7 0.2 9.3e-24 84.2 0.2 1.8 1 0 0 1 1 1 1 MIF4G domain MA3 PF02847.17 KKK16999.1 - 1e-18 67.4 0.1 3.3e-18 65.7 0.0 1.9 2 0 0 2 2 2 1 MA3 domain SRP14 PF02290.15 KKK17000.1 - 2.4e-27 95.1 0.2 3.9e-27 94.5 0.2 1.3 1 0 0 1 1 1 1 Signal recognition particle 14kD protein Inp1 PF12634.7 KKK17001.1 - 2.1e-39 134.7 0.0 5e-39 133.4 0.0 1.7 2 0 0 2 2 2 1 Inheritance of peroxisomes protein 1 EI24 PF07264.11 KKK17002.1 - 1.6e-11 44.7 1.9 5.7e-10 39.7 1.9 2.2 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) DUF3742 PF12553.8 KKK17002.1 - 0.1 12.7 0.6 0.24 11.5 0.0 1.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3742) FmdA_AmdA PF03069.15 KKK17003.1 - 4.7e-181 601.6 0.0 5.4e-181 601.4 0.0 1.0 1 0 0 1 1 1 1 Acetamidase/Formamidase family FAD_binding_3 PF01494.19 KKK17004.1 - 4.8e-18 65.5 2.0 2.8e-17 63.0 2.0 1.9 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KKK17004.1 - 9.7e-07 28.9 0.3 2.5e-06 27.6 0.3 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KKK17004.1 - 0.001 18.7 1.4 0.0019 17.9 0.7 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KKK17004.1 - 0.0061 15.8 0.3 0.019 14.2 0.3 1.8 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KKK17004.1 - 0.036 13.1 0.5 0.036 13.1 0.5 2.0 2 1 1 3 3 3 0 FAD binding domain IncF PF17626.2 KKK17005.1 - 0.014 15.7 0.3 0.055 13.8 0.3 2.1 1 0 0 1 1 1 0 Inclusion membrane protein F Macoilin PF09726.9 KKK17005.1 - 3.9 5.9 16.8 5.3 5.5 16.8 1.2 1 0 0 1 1 1 0 Macoilin family GREB1 PF15782.5 KKK17005.1 - 5.5 4.0 18.9 7.2 3.6 18.9 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer TFIIA PF03153.13 KKK17005.1 - 9.9 6.0 17.5 14 5.5 17.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Gly-zipper_Omp PF13488.6 KKK17024.1 - 0.017 15.1 0.7 0.017 15.1 0.7 1.8 2 0 0 2 2 2 0 Glycine zipper DUF1254 PF06863.12 KKK17024.1 - 0.091 12.8 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1254) Glyoxalase PF00903.25 KKK17024.1 - 0.11 12.6 0.0 1.6 9.0 0.0 2.8 2 1 1 3 3 3 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Rick_17kDa_Anti PF05433.15 KKK17024.1 - 0.89 9.5 9.4 0.061 13.2 3.7 2.0 2 0 0 2 2 2 0 Glycine zipper 2TM domain XPG_I PF00867.18 KKK17025.1 - 2.7e-32 111.0 1.4 1.1e-31 109.1 0.0 2.4 2 0 0 2 2 2 1 XPG I-region XPG_N PF00752.17 KKK17025.1 - 1e-24 86.9 0.5 5.6e-24 84.5 0.0 2.3 2 0 0 2 2 2 1 XPG N-terminal domain 5_3_exonuc PF01367.20 KKK17025.1 - 5.6e-05 23.7 0.4 0.00039 21.0 0.0 2.5 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold Zn_clus PF00172.18 KKK17026.1 - 3.8e-09 36.5 8.1 6e-09 35.9 8.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KKK17026.1 - 9.8e-08 31.3 0.5 2.4e-07 30.1 0.5 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Acyl-CoA_dh_1 PF00441.24 KKK17027.1 - 4.6e-25 88.6 0.3 7.3e-25 87.9 0.3 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KKK17027.1 - 3.2e-24 85.8 0.1 5.8e-24 84.9 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KKK17027.1 - 4.9e-17 61.9 0.0 9.6e-17 61.0 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KKK17027.1 - 7.5e-08 32.7 0.3 1.6e-07 31.6 0.3 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain UQ_con PF00179.26 KKK17028.1 - 1.6e-43 147.7 0.1 1.8e-43 147.5 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KKK17028.1 - 0.0022 17.7 0.0 0.0026 17.5 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 KKK17028.1 - 0.014 15.6 0.0 0.02 15.1 0.0 1.2 1 0 0 1 1 1 0 RWD domain UEV PF05743.13 KKK17028.1 - 0.027 14.3 0.1 0.046 13.6 0.1 1.3 1 1 0 1 1 1 0 UEV domain CENP-R PF06729.12 KKK17029.1 - 0.0095 15.9 0.9 0.019 14.9 0.0 1.8 2 0 0 2 2 2 1 Kinetochore component, CENP-R Linker_histone PF00538.19 KKK17030.1 - 4.8e-28 97.3 0.2 4.8e-28 97.3 0.2 2.1 2 0 0 2 2 2 1 linker histone H1 and H5 family Ribosomal_S9 PF00380.19 KKK17033.1 - 3.8e-23 82.3 0.2 4.2e-23 82.2 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 LON_substr_bdg PF02190.16 KKK17034.1 - 2e-27 96.4 0.0 2.6e-27 96.1 0.0 1.1 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain zf-C3HC4_2 PF13923.6 KKK17034.1 - 6.3e-11 41.9 16.4 1.4e-10 40.8 9.2 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KKK17034.1 - 6e-10 39.0 19.8 2e-07 30.9 3.9 3.4 3 0 0 3 3 3 2 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KKK17034.1 - 8.1e-10 38.4 12.5 1.5e-08 34.3 4.9 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KKK17034.1 - 1.5e-09 37.7 14.5 9.9e-07 28.6 6.6 2.4 2 0 0 2 2 2 2 zinc-RING finger domain zf-RING_2 PF13639.6 KKK17034.1 - 1.6e-08 34.7 15.6 6.5e-07 29.6 7.9 2.7 2 0 0 2 2 2 2 Ring finger domain zf-C3HC4 PF00097.25 KKK17034.1 - 1.8e-08 34.1 13.1 2.7e-06 27.2 8.2 2.4 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KKK17034.1 - 2.1e-06 27.5 6.6 2.1e-06 27.5 6.6 2.4 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KKK17034.1 - 2.7e-05 24.2 6.5 2.7e-05 24.2 6.5 3.0 3 1 0 3 3 2 2 zinc finger of C3HC4-type, RING zf-P11 PF03854.14 KKK17034.1 - 0.0011 18.6 5.8 0.0011 18.6 5.8 1.9 2 0 0 2 2 1 1 P-11 zinc finger zf-RING_10 PF16685.5 KKK17034.1 - 0.0012 18.9 5.9 0.0012 18.9 5.9 2.2 2 0 0 2 2 2 1 zinc RING finger of MSL2 zf-rbx1 PF12678.7 KKK17034.1 - 0.0063 16.8 4.3 0.016 15.5 4.3 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_4 PF14570.6 KKK17034.1 - 0.0087 15.8 5.9 0.033 14.0 4.3 2.6 2 1 0 2 2 2 1 RING/Ubox like zinc-binding domain U-box PF04564.15 KKK17034.1 - 0.023 14.8 0.0 0.05 13.8 0.0 1.5 1 0 0 1 1 1 0 U-box domain RRM_occluded PF16842.5 KKK17035.1 - 0.00071 19.4 0.0 0.092 12.6 0.0 2.5 2 0 0 2 2 2 2 Occluded RNA-recognition motif Peptidase_M19 PF01244.21 KKK17037.1 - 1.7e-102 342.9 0.0 2.1e-102 342.6 0.0 1.1 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) WD40 PF00400.32 KKK17038.1 - 9.1e-47 156.1 15.6 5.1e-08 33.5 0.2 8.1 7 2 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKK17038.1 - 3.5e-11 43.3 0.7 0.00091 19.5 0.0 4.4 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KKK17038.1 - 2.7e-06 26.3 0.2 0.0001 21.1 0.2 2.5 3 0 0 3 3 3 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 KKK17038.1 - 0.0011 17.9 0.2 6.6 5.3 0.0 3.1 3 0 0 3 3 3 3 Nup133 N terminal like DUF1192 PF06698.11 KKK17038.1 - 0.063 13.3 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) ABC_tran_CTD PF16326.5 KKK17038.1 - 0.066 13.5 0.1 0.13 12.5 0.1 1.4 1 0 0 1 1 1 0 ABC transporter C-terminal domain Hira PF07569.11 KKK17038.1 - 0.13 12.0 0.9 6.4 6.4 0.1 2.6 3 0 0 3 3 3 0 TUP1-like enhancer of split SlyX PF04102.12 KKK17038.1 - 0.14 12.8 0.1 0.27 11.9 0.1 1.4 1 0 0 1 1 1 0 SlyX DUF4013 PF13197.6 KKK17038.1 - 0.25 11.2 0.0 0.45 10.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4013) Glyco_transf_34 PF05637.12 KKK17039.1 - 7.6e-14 52.0 0.0 3.6e-09 36.7 0.0 2.2 1 1 1 2 2 2 2 galactosyl transferase GMA12/MNN10 family DUF273 PF03314.14 KKK17039.1 - 0.032 13.8 0.0 0.05 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF273 Nucleotid_trans PF03407.16 KKK17039.1 - 0.18 11.7 0.0 0.27 11.2 0.0 1.2 1 0 0 1 1 1 0 Nucleotide-diphospho-sugar transferase Pkinase PF00069.25 KKK17041.1 - 9e-41 140.0 0.0 1.8e-39 135.7 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Ribonuc_2-5A PF06479.12 KKK17041.1 - 1.9e-39 134.7 0.0 3.2e-39 134.0 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase_Tyr PF07714.17 KKK17041.1 - 1.3e-19 70.5 0.0 7.7e-19 68.0 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase PQQ PF01011.21 KKK17041.1 - 1.9e-05 24.3 0.0 0.11 12.4 0.0 3.1 3 0 0 3 3 3 2 PQQ enzyme repeat Pkinase_fungal PF17667.1 KKK17041.1 - 0.00054 18.9 0.0 0.0015 17.4 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase PQQ_2 PF13360.6 KKK17041.1 - 0.0048 16.5 0.0 0.054 13.1 0.1 2.2 1 1 1 2 2 2 1 PQQ-like domain Kdo PF06293.14 KKK17041.1 - 0.021 14.2 0.0 0.041 13.2 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family p450 PF00067.22 KKK17042.1 - 1.7e-79 267.8 0.0 1.9e-79 267.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 IBR PF01485.21 KKK17049.1 - 4.5e-06 26.8 2.5 4.5e-06 26.8 2.5 4.7 4 1 1 5 5 5 2 IBR domain, a half RING-finger domain DMA PF03474.14 KKK17049.1 - 0.01 15.4 0.0 0.16 11.6 0.0 2.4 2 0 0 2 2 2 0 DMRTA motif Chalcone_2 PF16035.5 KKK17049.1 - 0.074 12.8 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Chalcone isomerase like Cation_efflux PF01545.21 KKK17050.1 - 2.2e-15 56.9 6.8 2.9e-15 56.6 6.8 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 KKK17050.1 - 3.8e-11 42.9 0.7 7.3e-11 42.0 0.1 1.7 2 0 0 2 2 2 1 Dimerisation domain of Zinc Transporter Aminotran_3 PF00202.21 KKK17051.1 - 1.3e-110 369.9 0.0 1.6e-110 369.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 KKK17051.1 - 7e-05 22.2 0.0 0.00011 21.6 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class I and II Lactonase PF10282.9 KKK17052.1 - 2.8e-23 82.7 0.0 3.6e-23 82.4 0.0 1.1 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Metallophos PF00149.28 KKK17053.1 - 1.4e-10 42.1 1.2 9e-10 39.4 0.5 2.1 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Coilin_N PF15862.5 KKK17053.1 - 0.0021 17.8 0.0 0.029 14.2 0.0 2.6 2 1 0 2 2 2 1 Coilin N-terminus SR-25 PF10500.9 KKK17053.1 - 0.0022 17.7 0.6 0.0022 17.7 0.6 1.9 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein AP3D1 PF06375.11 KKK17053.1 - 5.8 7.1 11.5 0.8 9.9 6.0 2.1 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 SPT6_acidic PF14632.6 KKK17053.1 - 7 7.3 11.4 14 6.3 0.7 2.4 2 0 0 2 2 2 0 Acidic N-terminal SPT6 14-3-3 PF00244.20 KKK17055.1 - 3.1e-09 36.7 0.1 5.4e-09 35.9 0.1 1.3 1 0 0 1 1 1 1 14-3-3 protein DUF1674 PF07896.12 KKK17056.1 - 5.9e-19 68.3 1.7 5.9e-19 68.3 1.7 2.2 2 1 1 3 3 3 1 Protein of unknown function (DUF1674) DUF836 PF05768.14 KKK17057.1 - 4e-12 46.4 0.0 4.9e-12 46.1 0.0 1.1 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Glutaredoxin PF00462.24 KKK17057.1 - 0.1 12.9 0.1 0.15 12.3 0.1 1.4 1 0 0 1 1 1 0 Glutaredoxin CHORD PF04968.12 KKK17058.1 - 1.7e-50 169.6 21.9 9.6e-27 93.5 7.4 2.2 2 0 0 2 2 2 2 CHORD CS PF04969.16 KKK17058.1 - 7.1e-14 52.6 0.1 1.1e-13 52.0 0.1 1.3 1 0 0 1 1 1 1 CS domain Pheromone PF08015.11 KKK17058.1 - 0.02 15.9 0.5 0.048 14.7 0.5 1.6 1 0 0 1 1 1 0 Fungal mating-type pheromone BTK PF00779.19 KKK17058.1 - 0.27 11.1 12.2 0.28 11.0 1.4 2.9 3 0 0 3 3 3 0 BTK motif LSM PF01423.22 KKK17059.1 - 0.00062 19.4 0.0 0.00083 19.0 0.0 1.2 1 0 0 1 1 1 1 LSM domain SelK_SelG PF10961.8 KKK17059.1 - 0.04 14.5 8.1 0.055 14.1 8.1 1.2 1 0 0 1 1 1 0 Selenoprotein SelK_SelG DUF5549 PF17703.1 KKK17059.1 - 0.06 13.0 1.3 0.068 12.8 1.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5549) MTS PF05175.14 KKK17060.1 - 8.4e-05 22.2 0.3 0.23 11.0 0.0 2.2 1 1 1 2 2 2 2 Methyltransferase small domain Methyltransf_12 PF08242.12 KKK17060.1 - 0.00074 20.2 5.3 0.0017 19.0 3.5 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KKK17060.1 - 0.065 13.1 0.0 0.33 10.8 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Fungal_trans PF04082.18 KKK17060.1 - 0.098 11.7 0.7 4.5 6.2 0.0 2.3 3 0 0 3 3 3 0 Fungal specific transcription factor domain Methyltransf_25 PF13649.6 KKK17060.1 - 0.11 13.2 0.0 0.42 11.4 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Menin PF05053.13 KKK17060.1 - 0.25 9.7 1.8 0.31 9.4 1.8 1.1 1 0 0 1 1 1 0 Menin Phos_pyr_kin PF08543.12 KKK17061.1 - 6.6e-84 281.1 0.3 8.7e-84 280.7 0.3 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.16 KKK17061.1 - 6.8e-53 179.6 0.1 9.7e-53 179.1 0.1 1.2 1 0 0 1 1 1 1 TENA/THI-4/PQQC family PfkB PF00294.24 KKK17061.1 - 2.1e-05 24.0 0.2 0.013 14.8 0.0 2.2 2 0 0 2 2 2 2 pfkB family carbohydrate kinase HK PF02110.15 KKK17061.1 - 0.00017 21.0 0.6 0.0094 15.4 0.0 2.3 2 0 0 2 2 2 2 Hydroxyethylthiazole kinase family Carb_kinase PF01256.17 KKK17061.1 - 0.0015 18.1 2.5 0.0022 17.5 0.6 2.1 1 1 1 2 2 2 1 Carbohydrate kinase DNA_pol_B PF00136.21 KKK17062.1 - 7.5e-117 390.8 0.8 1e-116 390.4 0.8 1.2 1 0 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.10 KKK17062.1 - 3.7e-69 232.2 1.5 7e-69 231.3 1.5 1.5 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.19 KKK17062.1 - 2.6e-42 145.2 0.0 5.9e-42 144.0 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.8 KKK17062.1 - 4.1e-24 84.4 6.9 4.1e-24 84.4 6.9 2.7 2 0 0 2 2 2 1 DNA polymerase alpha subunit p180 N terminal DNA_pol_B_2 PF03175.13 KKK17062.1 - 0.021 13.7 0.0 0.046 12.6 0.0 1.5 1 0 0 1 1 1 0 DNA polymerase type B, organellar and viral CDC45 PF02724.14 KKK17062.1 - 7 4.8 6.7 14 3.8 6.7 1.4 1 0 0 1 1 1 0 CDC45-like protein HsbA PF12296.8 KKK17063.1 - 2.8e-13 50.4 10.5 2.1e-11 44.3 3.1 2.9 2 1 1 3 3 3 2 Hydrophobic surface binding protein A DUF3500 PF12006.8 KKK17063.1 - 0.074 12.5 0.1 0.089 12.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3500) DEAD PF00270.29 KKK17064.1 - 3e-48 163.9 0.0 3.9e-47 160.3 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KKK17064.1 - 2.2e-30 105.3 0.0 7.4e-30 103.6 0.0 1.9 1 1 1 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KKK17064.1 - 0.00068 19.7 0.0 0.0018 18.3 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 KKK17064.1 - 0.014 15.7 0.0 0.89 9.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain Helicase_C_2 PF13307.6 KKK17064.1 - 0.015 15.5 0.0 0.025 14.7 0.0 1.3 1 0 0 1 1 1 0 Helicase C-terminal domain ERCC3_RAD25_C PF16203.5 KKK17064.1 - 0.04 13.1 0.2 0.057 12.6 0.2 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase DUF2443 PF10398.9 KKK17064.1 - 0.11 12.6 0.2 0.25 11.4 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2443) POTRA_2 PF08479.11 KKK17064.1 - 0.14 12.0 0.0 0.35 10.7 0.0 1.6 1 0 0 1 1 1 0 POTRA domain, ShlB-type AAA_22 PF13401.6 KKK17064.1 - 0.24 11.7 0.5 18 5.6 0.0 3.2 4 0 0 4 4 4 0 AAA domain UTP25 PF06862.12 KKK17064.1 - 0.63 8.7 3.2 2.6 6.7 0.0 2.4 3 0 0 3 3 3 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Sugar_tr PF00083.24 KKK17065.1 - 1.4e-22 80.2 23.2 4.9e-14 52.0 4.9 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter RCC1 PF00415.18 KKK17066.1 - 5.3e-32 110.2 21.0 5.7e-08 33.3 0.1 8.1 7 2 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KKK17066.1 - 1.4e-20 72.5 19.4 2.1e-07 30.6 0.1 6.3 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat Rad9 PF04139.13 KKK17067.1 - 4e-51 173.9 2.7 5e-51 173.6 2.7 1.1 1 0 0 1 1 1 1 Rad9 Rad1 PF02144.16 KKK17067.1 - 1.1e-05 24.6 2.6 0.00017 20.8 2.1 2.3 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 DUF2683 PF10884.8 KKK17067.1 - 0.046 14.0 0.0 14 6.0 0.1 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2683) LRR_4 PF12799.7 KKK17068.1 - 0.005 17.2 4.9 9.9 6.7 0.1 5.6 2 1 3 5 5 5 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KKK17068.1 - 0.028 14.2 1.4 56 3.6 0.0 5.5 6 0 0 6 6 6 0 Leucine rich repeat GRASP55_65 PF04495.14 KKK17069.1 - 1e-39 136.0 0.0 2.1e-36 125.3 0.0 2.2 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain PDZ_6 PF17820.1 KKK17069.1 - 0.0022 17.8 0.0 0.5 10.3 0.0 2.6 2 0 0 2 2 2 2 PDZ domain ApoO PF09769.9 KKK17070.1 - 7.9e-42 142.3 0.2 8.6e-41 138.9 0.1 2.0 2 0 0 2 2 2 1 Apolipoprotein O Mito_fiss_reg PF05308.11 KKK17070.1 - 7.6 6.5 9.8 13 5.8 9.8 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator Peptidase_M3 PF01432.20 KKK17071.1 - 8.5e-115 384.6 0.0 1.1e-114 384.2 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 Acetyltransf_17 PF17668.1 KKK17071.1 - 0.074 13.9 0.0 2.2 9.1 0.0 2.6 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Peptidase_M50B PF13398.6 KKK17071.1 - 0.16 11.5 0.2 0.3 10.7 0.2 1.3 1 0 0 1 1 1 0 Peptidase M50B-like FAM184 PF15665.5 KKK17072.1 - 3e-06 27.2 71.9 1.6e-05 24.8 36.7 7.4 1 1 4 6 6 6 3 Family with sequence similarity 184, A and B Pox_A_type_inc PF04508.12 KKK17072.1 - 0.00011 21.8 7.9 8.1 6.5 0.2 6.6 5 0 0 5 5 5 3 Viral A-type inclusion protein repeat Filament PF00038.21 KKK17072.1 - 0.00057 19.6 168.0 0.027 14.1 15.2 8.7 1 1 8 9 9 9 4 Intermediate filament protein HIP1_clath_bdg PF16515.5 KKK17072.1 - 0.0087 16.7 10.9 0.0087 16.7 10.9 11.9 2 1 11 13 13 13 3 Clathrin-binding domain of Huntingtin-interacting protein 1 Pkinase PF00069.25 KKK17073.1 - 2.1e-46 158.4 0.1 1.3e-23 83.7 0.0 3.3 3 0 0 3 3 3 2 Protein kinase domain FKBP_C PF00254.28 KKK17073.1 - 2.9e-31 107.6 0.0 6.7e-31 106.5 0.0 1.6 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase NPL PF17800.1 KKK17073.1 - 3e-31 108.1 0.4 8.9e-31 106.6 0.0 2.1 2 0 0 2 2 2 1 Nucleoplasmin-like domain Pkinase_Tyr PF07714.17 KKK17073.1 - 4.3e-19 68.8 0.0 9.1e-11 41.5 0.0 3.1 3 0 0 3 3 3 2 Protein tyrosine kinase APH PF01636.23 KKK17073.1 - 0.00016 21.7 0.3 0.00039 20.4 0.3 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family Noggin PF05806.12 KKK17073.1 - 6.1 6.7 6.0 2.5 8.0 0.0 2.7 2 0 0 2 2 2 0 Noggin DUF3591 PF12157.8 KKK17074.1 - 2.4e-178 593.3 0.0 3.1e-178 593.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) zf-CCHC PF00098.23 KKK17074.1 - 0.0051 16.8 0.7 0.0086 16.1 0.7 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 KKK17074.1 - 0.0063 16.3 1.2 0.016 15.1 1.2 1.7 1 0 0 1 1 1 1 Zinc knuckle Methyltransf_15 PF09445.10 KKK17075.1 - 8.5e-52 175.1 0.0 1.1e-51 174.7 0.0 1.1 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Met_10 PF02475.16 KKK17075.1 - 2.7e-12 46.8 0.0 3.6e-12 46.5 0.0 1.1 1 0 0 1 1 1 1 Met-10+ like-protein Cons_hypoth95 PF03602.15 KKK17075.1 - 4.6e-06 26.4 0.0 6.6e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 UPF0020 PF01170.18 KKK17075.1 - 6.6e-05 22.7 0.0 0.00011 21.9 0.0 1.5 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_18 PF12847.7 KKK17075.1 - 0.00012 22.0 0.0 0.00018 21.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKK17075.1 - 0.0035 18.0 0.0 0.0056 17.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KKK17075.1 - 0.042 14.5 0.0 0.07 13.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_5 PF01795.19 KKK17075.1 - 0.055 13.0 0.0 0.077 12.5 0.0 1.1 1 0 0 1 1 1 0 MraW methylase family DNA_methylase PF00145.17 KKK17075.1 - 0.12 11.7 0.0 0.23 10.8 0.0 1.5 1 1 0 1 1 1 0 C-5 cytosine-specific DNA methylase Methyltrans_SAM PF10672.9 KKK17075.1 - 0.18 10.9 0.0 0.26 10.4 0.0 1.1 1 0 0 1 1 1 0 S-adenosylmethionine-dependent methyltransferase PTPA PF03095.15 KKK17076.1 - 7.7e-118 393.3 0.0 8.9e-118 393.1 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein DUF572 PF04502.13 KKK17077.1 - 2.4e-19 70.1 5.6 2.9e-19 69.9 5.6 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) Vps26 PF03643.15 KKK17078.1 - 2.9e-130 433.2 0.4 3.4e-130 433.0 0.4 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.29 KKK17078.1 - 0.00025 21.1 0.2 0.66 10.0 0.1 2.9 3 0 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 KKK17078.1 - 0.0032 17.9 0.2 0.05 14.0 0.0 2.6 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain 2-oxoacid_dh PF00198.23 KKK17079.1 - 5.9e-77 258.2 0.0 8.5e-77 257.7 0.0 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 KKK17079.1 - 1.8e-13 50.1 0.0 3.4e-13 49.2 0.0 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 KKK17079.1 - 1.1e-12 48.1 0.3 4.8e-12 46.0 0.1 2.2 2 0 0 2 2 2 1 e3 binding domain SRA1 PF07304.11 KKK17079.1 - 0.17 11.7 0.2 0.41 10.4 0.2 1.6 1 0 0 1 1 1 0 Steroid receptor RNA activator (SRA1) MINDY_DUB PF04424.13 KKK17080.1 - 1.8e-13 50.6 0.0 3.4e-13 49.6 0.0 1.4 1 0 0 1 1 1 1 MINDY deubiquitinase RSN1_7TM PF02714.15 KKK17081.1 - 7.1e-87 291.2 26.3 1.3e-86 290.4 18.5 2.5 3 0 0 3 3 3 2 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 KKK17081.1 - 2.2e-41 141.2 3.1 2.2e-41 141.2 3.1 2.5 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 KKK17081.1 - 6.6e-33 114.4 0.1 1.3e-32 113.4 0.1 1.5 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 KKK17081.1 - 3.8e-27 94.3 0.6 1.1e-26 92.8 0.6 1.7 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter Aldo_ket_red PF00248.21 KKK17082.1 - 1e-19 70.9 0.0 4.4e-19 68.8 0.0 1.9 1 1 0 1 1 1 1 Aldo/keto reductase family HSF_DNA-bind PF00447.17 KKK17083.1 - 8.1e-29 100.1 0.3 1.9e-28 98.9 0.3 1.7 1 0 0 1 1 1 1 HSF-type DNA-binding TYA PF01021.19 KKK17083.1 - 0.021 15.2 3.2 0.1 12.9 3.2 2.2 1 0 0 1 1 1 0 TYA transposon protein TMF_DNA_bd PF12329.8 KKK17083.1 - 0.021 14.8 2.4 0.23 11.5 0.1 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding TRAF_BIRC3_bd PF16673.5 KKK17083.1 - 0.037 13.8 0.9 0.1 12.4 0.9 1.7 1 0 0 1 1 1 0 TNF receptor-associated factor BIRC3 binding domain Ets PF00178.22 KKK17083.1 - 0.07 13.6 0.0 0.16 12.4 0.0 1.5 1 0 0 1 1 1 0 Ets-domain CENP-F_leu_zip PF10473.9 KKK17083.1 - 0.15 12.1 0.6 15 5.6 0.0 2.2 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 APG6_N PF17675.1 KKK17083.1 - 0.53 10.8 2.7 0.8 10.2 0.2 2.4 3 0 0 3 3 3 0 Apg6 coiled-coil region MRP-L28 PF09812.9 KKK17083.1 - 0.65 10.1 3.5 0.41 10.8 1.0 1.9 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L28 APC_u15 PF16636.5 KKK17083.1 - 2.9 8.4 4.9 12 6.4 0.1 3.1 3 0 0 3 3 3 0 Unstructured region on APC between APC_crr regions 5 and 6 Pro_isomerase PF00160.21 KKK17084.1 - 2.3e-38 131.9 0.0 4.8e-38 130.9 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF3431 PF11913.8 KKK17085.1 - 2.7e-86 288.8 0.2 2.7e-86 288.8 0.2 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3431) SR-25 PF10500.9 KKK17085.1 - 0.018 14.7 3.7 0.025 14.2 3.7 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein IMUP PF15761.5 KKK17085.1 - 0.33 11.7 4.9 0.59 10.8 4.9 1.3 1 0 0 1 1 1 0 Immortalisation up-regulated protein His_Phos_2 PF00328.22 KKK17086.1 - 5.5e-07 29.3 0.6 0.00046 19.7 0.0 2.9 1 1 1 2 2 2 1 Histidine phosphatase superfamily (branch 2) Macoilin PF09726.9 KKK17086.1 - 0.36 9.3 1.1 0.48 8.9 1.1 1.1 1 0 0 1 1 1 0 Macoilin family SR-25 PF10500.9 KKK17086.1 - 1.5 8.4 20.7 2.4 7.7 20.7 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Rep_fac_C PF08542.11 KKK17087.1 - 1.8e-17 63.5 0.0 4.9e-17 62.1 0.0 1.8 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.29 KKK17087.1 - 1.3e-16 61.2 0.0 2.3e-16 60.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 KKK17087.1 - 3.8e-12 46.3 0.1 2e-11 43.9 0.1 2.1 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.15 KKK17087.1 - 9.8e-11 41.9 0.0 1.6e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_assoc_2 PF16193.5 KKK17087.1 - 5.9e-07 29.7 0.0 3.3e-06 27.3 0.0 2.3 2 1 1 3 3 2 1 AAA C-terminal domain AAA_11 PF13086.6 KKK17087.1 - 1.4e-06 28.3 0.3 4.6e-05 23.3 0.0 2.2 1 1 1 2 2 2 1 AAA domain AAA_30 PF13604.6 KKK17087.1 - 1.7e-06 27.9 0.0 3.3e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KKK17087.1 - 2.1e-06 28.3 0.0 1.7e-05 25.3 0.0 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KKK17087.1 - 6.8e-06 26.4 0.2 4.7e-05 23.7 0.1 2.4 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.12 KKK17087.1 - 2.3e-05 24.2 0.0 7.7e-05 22.5 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KKK17087.1 - 2.3e-05 24.4 0.1 9.5e-05 22.4 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) DNA_pol3_delta PF06144.13 KKK17087.1 - 3.5e-05 23.6 0.0 7e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit DUF815 PF05673.13 KKK17087.1 - 3.5e-05 23.1 0.0 6.1e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_24 PF13479.6 KKK17087.1 - 4.6e-05 23.2 0.0 7.4e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KKK17087.1 - 0.00012 22.4 0.1 0.00044 20.6 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_3 PF07726.11 KKK17087.1 - 0.00016 21.5 0.2 0.00051 19.9 0.1 2.0 2 1 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 KKK17087.1 - 0.00038 20.5 0.0 0.002 18.2 0.0 2.0 1 1 1 2 2 2 1 AAA domain PhoH PF02562.16 KKK17087.1 - 0.00082 18.9 0.0 0.44 10.0 0.0 2.3 2 0 0 2 2 2 2 PhoH-like protein ResIII PF04851.15 KKK17087.1 - 0.0028 17.7 0.0 0.096 12.7 0.0 2.2 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KKK17087.1 - 0.0036 17.1 0.1 0.023 14.4 0.0 2.0 1 1 1 2 2 2 1 DEAD/DEAH box helicase AAA_18 PF13238.6 KKK17087.1 - 0.0066 17.0 0.0 0.011 16.3 0.0 1.6 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 KKK17087.1 - 0.0088 15.4 0.1 0.11 11.8 0.1 2.5 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 KKK17087.1 - 0.01 16.1 0.0 0.02 15.1 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KKK17087.1 - 0.014 14.9 0.0 0.037 13.5 0.0 1.7 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF2075 PF09848.9 KKK17087.1 - 0.015 14.5 0.0 0.025 13.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) TniB PF05621.11 KKK17087.1 - 0.041 13.3 0.1 0.42 10.0 0.1 2.2 1 1 0 1 1 1 0 Bacterial TniB protein IstB_IS21 PF01695.17 KKK17087.1 - 0.044 13.5 0.0 0.32 10.7 0.0 2.1 1 1 0 1 1 1 0 IstB-like ATP binding protein NACHT PF05729.12 KKK17087.1 - 0.054 13.4 0.0 0.098 12.6 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_25 PF13481.6 KKK17087.1 - 0.056 13.0 0.0 0.18 11.4 0.0 1.7 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KKK17087.1 - 0.072 13.5 0.0 0.16 12.3 0.0 1.7 1 0 0 1 1 1 0 RNA helicase ATPase_2 PF01637.18 KKK17087.1 - 0.079 12.9 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Viral_helicase1 PF01443.18 KKK17087.1 - 0.14 11.9 0.0 0.36 10.5 0.0 1.7 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase P21-Arc PF04062.14 KKK17088.1 - 6.1e-73 244.6 0.0 6.8e-73 244.4 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit Gcd10p PF04189.13 KKK17089.1 - 1.8e-121 404.9 0.0 2.3e-121 404.6 0.0 1.1 1 0 0 1 1 1 1 Gcd10p family Methyltr_RsmB-F PF01189.17 KKK17090.1 - 8.3e-73 244.3 0.1 1.8e-72 243.2 0.0 1.7 2 0 0 2 2 2 1 16S rRNA methyltransferase RsmB/F Methyltr_RsmF_N PF17125.5 KKK17090.1 - 1.6e-07 31.7 0.0 4.3e-07 30.3 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of 16S rRNA methyltransferase RsmF FtsJ PF01728.19 KKK17090.1 - 0.028 14.5 0.0 0.059 13.5 0.0 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase DDE_Tnp_1_6 PF13751.6 KKK17090.1 - 1.8 8.8 5.6 5.1 7.3 5.6 1.7 1 0 0 1 1 1 0 Transposase DDE domain Blt1 PF12754.7 KKK17091.1 - 1.4e-62 210.5 0.1 4.3e-62 208.9 0.0 1.7 2 0 0 2 2 2 1 Blt1 N-terminal domain Blt1_C PF17183.4 KKK17091.1 - 1.7e-23 82.0 0.5 1.7e-23 82.0 0.5 1.7 2 0 0 2 2 2 1 Get5 carboxyl domain Striatin PF08232.12 KKK17092.1 - 1.8e-45 155.3 10.4 1.8e-45 155.3 10.4 2.3 2 0 0 2 2 2 1 Striatin family WD40 PF00400.32 KKK17092.1 - 1.6e-24 85.7 19.9 0.00017 22.3 0.0 7.6 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKK17092.1 - 0.00077 19.7 0.1 4.3 7.7 0.0 4.6 3 1 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KKK17092.1 - 0.0051 16.7 0.0 0.0099 15.8 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 KKK17092.1 - 0.028 12.9 0.0 0.064 11.8 0.0 1.5 1 0 0 1 1 1 0 Cytochrome D1 heme domain Ge1_WD40 PF16529.5 KKK17092.1 - 0.21 10.5 0.0 0.46 9.4 0.0 1.6 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Ten_N PF06484.12 KKK17092.1 - 0.83 9.5 10.8 1.7 8.5 10.8 1.5 1 0 0 1 1 1 0 Teneurin Intracellular Region PIG-P PF08510.12 KKK17093.1 - 2.5e-52 175.9 0.7 4.2e-52 175.2 0.7 1.3 1 0 0 1 1 1 1 PIG-P DPM2 PF07297.12 KKK17093.1 - 1.6 9.1 8.8 3 8.2 8.8 1.3 1 0 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) MORN PF02493.20 KKK17094.1 - 2.2e-13 49.2 25.2 3.4e-05 23.5 0.4 4.6 4 0 0 4 4 4 4 MORN repeat zf-C3HC4_3 PF13920.6 KKK17094.1 - 8.5e-11 41.5 10.3 1.4e-10 40.8 10.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) UCH PF00443.29 KKK17094.1 - 3.5e-10 39.8 0.0 8.2e-10 38.6 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase USP7_ICP0_bdg PF12436.8 KKK17094.1 - 0.00013 21.4 0.0 0.00025 20.4 0.0 1.4 1 0 0 1 1 1 1 ICP0-binding domain of Ubiquitin-specific protease 7 Prok-RING_4 PF14447.6 KKK17094.1 - 0.012 15.5 10.6 0.025 14.4 10.6 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 KKK17094.1 - 0.18 12.2 11.1 0.37 11.1 11.1 1.6 1 0 0 1 1 1 0 Ring finger domain zf-RING_5 PF14634.6 KKK17094.1 - 0.23 11.4 11.3 0.45 10.5 11.3 1.5 1 0 0 1 1 1 0 zinc-RING finger domain Sporozoite_P67 PF05642.11 KKK17095.1 - 0.039 12.0 11.2 0.054 11.6 11.2 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Apt1 PF10351.9 KKK17095.1 - 0.048 12.5 5.3 0.05 12.5 5.3 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain SDA1 PF05285.12 KKK17095.1 - 0.062 12.7 0.8 0.067 12.6 0.8 1.1 1 0 0 1 1 1 0 SDA1 RNA_pol_Rbc25 PF08292.12 KKK17095.1 - 0.17 12.1 0.0 0.82 9.9 0.1 2.0 2 0 0 2 2 2 0 RNA polymerase III subunit Rpc25 BUD22 PF09073.10 KKK17095.1 - 0.19 11.0 7.5 0.28 10.5 7.5 1.2 1 0 0 1 1 1 0 BUD22 Macoilin PF09726.9 KKK17095.1 - 0.28 9.7 12.3 0.34 9.4 12.3 1.0 1 0 0 1 1 1 0 Macoilin family CENP-B_dimeris PF09026.10 KKK17095.1 - 0.79 10.1 7.0 2.1 8.8 2.5 2.2 2 0 0 2 2 2 0 Centromere protein B dimerisation domain PI3K_1B_p101 PF10486.9 KKK17095.1 - 1.2 6.8 8.2 1.5 6.5 8.2 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit CAML PF14963.6 KKK17095.1 - 5.9 6.9 5.8 8.3 6.4 5.8 1.1 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand Abhydro_lipase PF04083.16 KKK17096.1 - 2e-22 78.5 0.0 4.6e-22 77.4 0.0 1.6 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 KKK17096.1 - 4e-06 26.7 0.3 8.6e-06 25.6 0.1 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KKK17096.1 - 0.00075 18.8 0.0 0.0021 17.4 0.0 1.8 2 0 0 2 2 2 1 Serine aminopeptidase, S33 UL42 PF17638.2 KKK17097.1 - 0.56 10.2 1.8 1 9.3 1.8 1.4 1 0 0 1 1 1 0 HCMV UL42 FtsL PF04999.13 KKK17097.1 - 0.73 9.9 2.5 0.87 9.6 1.0 1.8 2 0 0 2 2 2 0 Cell division protein FtsL Sugar_tr PF00083.24 KKK17098.1 - 5.6e-128 427.6 23.3 6.4e-128 427.4 23.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKK17098.1 - 4.1e-24 85.2 54.4 5.3e-21 74.9 28.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KKK17098.1 - 5.4e-07 28.8 0.0 3.1e-06 26.3 0.0 2.5 1 1 0 1 1 1 1 MFS_1 like family Ilm1 PF10311.9 KKK17098.1 - 0.13 11.9 0.7 0.23 11.1 0.7 1.4 1 0 0 1 1 1 0 Increased loss of mitochondrial DNA protein 1 MSP1b PF03429.13 KKK17098.1 - 0.18 9.9 0.4 0.26 9.3 0.4 1.1 1 0 0 1 1 1 0 Major surface protein 1B Metallophos PF00149.28 KKK17099.1 - 0.00015 22.4 2.3 0.00053 20.6 2.3 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase MFS_1 PF07690.16 KKK17100.1 - 3.1e-33 115.2 41.7 3.1e-33 115.2 41.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KKK17100.1 - 2.3e-13 49.8 9.2 2.3e-13 49.8 9.2 2.3 2 1 0 2 2 2 1 Sugar (and other) transporter 4HBT PF03061.22 KKK17101.1 - 5.7e-09 36.2 0.0 1.1e-08 35.4 0.0 1.5 1 0 0 1 1 1 1 Thioesterase superfamily HATPase_c PF02518.26 KKK17102.1 - 9e-27 93.8 0.0 4.6e-26 91.5 0.0 2.2 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KKK17102.1 - 2.8e-24 85.4 1.4 5.3e-24 84.5 0.4 1.9 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 KKK17102.1 - 5.9e-15 55.1 0.0 1.8e-14 53.5 0.0 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 KKK17102.1 - 0.0015 18.8 0.7 0.2 12.0 0.0 2.8 2 0 0 2 2 2 1 HAMP domain IFT57 PF10498.9 KKK17102.1 - 0.13 11.2 1.9 0.24 10.4 1.9 1.3 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 LSM PF01423.22 KKK17103.1 - 1.8e-18 65.9 0.1 2.5e-18 65.5 0.1 1.1 1 0 0 1 1 1 1 LSM domain SIR2 PF02146.17 KKK17104.1 - 3.7e-14 53.0 0.0 9.2e-14 51.8 0.0 1.6 1 1 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.22 KKK17104.1 - 0.037 13.7 0.0 0.058 13.1 0.0 1.3 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, central domain Glyco_hydro_18 PF00704.28 KKK17106.1 - 4.4e-85 286.1 2.4 5.2e-85 285.9 2.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Pkinase PF00069.25 KKK17107.1 - 6.3e-56 189.7 0.0 9.4e-56 189.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK17107.1 - 5.2e-31 107.9 0.0 7.8e-30 104.0 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KKK17107.1 - 0.0022 17.0 0.0 0.0035 16.3 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Pox_ser-thr_kin PF05445.11 KKK17107.1 - 0.11 11.4 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kdo PF06293.14 KKK17107.1 - 0.13 11.6 0.1 0.23 10.8 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ThiS PF02597.20 KKK17108.1 - 0.096 13.3 1.1 0.16 12.7 0.3 1.8 2 0 0 2 2 2 0 ThiS family zf-C2H2 PF00096.26 KKK17115.1 - 7.8e-09 35.5 17.9 0.00015 22.0 1.4 4.4 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KKK17115.1 - 0.00075 20.1 18.4 0.028 15.2 1.1 4.7 5 0 0 5 5 5 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KKK17115.1 - 0.25 11.8 8.4 18 6.0 1.1 3.8 3 0 0 3 3 3 0 Zinc-finger double domain zf-BED PF02892.15 KKK17115.1 - 0.3 11.1 2.0 0.84 9.7 2.0 1.8 1 0 0 1 1 1 0 BED zinc finger zf-Di19 PF05605.12 KKK17115.1 - 0.45 10.9 5.8 0.89 9.9 1.5 2.4 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_11 PF16622.5 KKK17115.1 - 8 6.3 7.0 1.7 8.5 0.5 3.0 3 0 0 3 3 3 0 zinc-finger C2H2-type Hexapep PF00132.24 KKK17124.1 - 3.3e-08 32.9 9.1 4.9e-05 22.9 3.6 4.2 4 1 0 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KKK17124.1 - 4.9e-05 23.0 0.4 0.00015 21.4 0.1 2.0 2 0 0 2 2 2 1 Hexapeptide repeat of succinyl-transferase MOSC_N PF03476.16 KKK17125.1 - 1.7e-20 73.1 0.0 1.8e-19 69.8 0.0 2.2 1 1 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.17 KKK17125.1 - 1.1e-16 61.0 0.1 2e-08 34.3 0.0 2.3 1 1 1 2 2 2 2 MOSC domain Ribosomal_S28e PF01200.18 KKK17146.1 - 2.8e-31 107.3 2.0 3.1e-31 107.2 2.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e GAS2 PF02187.17 KKK17147.1 - 6.6e-06 26.1 0.1 1.3e-05 25.2 0.1 1.4 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain Hus1 PF04005.12 KKK17148.1 - 7.9e-112 373.1 0.0 9e-112 372.9 0.0 1.0 1 0 0 1 1 1 1 Hus1-like protein DUF4552 PF15089.6 KKK17148.1 - 0.022 13.9 0.2 0.031 13.3 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4552) APS-reductase_C PF12139.8 KKK17148.1 - 0.073 13.3 0.0 0.17 12.1 0.0 1.6 1 0 0 1 1 1 0 Adenosine-5'-phosphosulfate reductase beta subunit SNRNP27 PF08648.12 KKK17149.1 - 1.1e-25 89.5 1.4 2.3e-25 88.4 1.4 1.6 1 0 0 1 1 1 1 U4/U6.U5 small nuclear ribonucleoproteins Apt1 PF10351.9 KKK17149.1 - 0.55 9.0 13.7 0.78 8.5 13.7 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain Sec16_C PF12931.7 KKK17150.1 - 2.7e-106 355.6 0.0 3.9e-106 355.1 0.0 1.3 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16_N PF12935.7 KKK17150.1 - 8.8e-70 235.6 22.3 8.8e-70 235.6 22.3 2.7 2 0 0 2 2 2 1 Vesicle coat trafficking protein Sec16 N-terminus Sec16 PF12932.7 KKK17150.1 - 1.6e-34 119.0 0.0 4.1e-34 117.7 0.0 1.8 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region MMtag PF10159.9 KKK17151.1 - 1.2e-33 115.2 3.7 1.2e-33 115.2 3.7 2.3 2 1 0 2 2 2 1 Multiple myeloma tumor-associated Glyco_hydro_63 PF03200.16 KKK17152.1 - 3.8e-170 566.9 0.4 3.4e-169 563.7 0.4 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 63 C-terminal domain Glyco_hydro_63N PF16923.5 KKK17152.1 - 1.2e-87 293.8 0.0 2e-86 289.8 0.0 2.2 2 0 0 2 2 2 1 Glycosyl hydrolase family 63 N-terminal domain DAO PF01266.24 KKK17152.1 - 3.6e-66 224.1 1.1 5.3e-66 223.6 1.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KKK17152.1 - 9e-06 25.8 0.2 2.7e-05 24.3 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KKK17152.1 - 0.0002 20.7 0.1 0.15 11.3 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Trehalase PF01204.18 KKK17152.1 - 0.0041 16.0 0.3 0.0078 15.1 0.3 1.4 1 0 0 1 1 1 1 Trehalase Trp_halogenase PF04820.14 KKK17152.1 - 0.0049 15.8 0.1 0.036 12.9 0.1 2.0 2 0 0 2 2 2 1 Tryptophan halogenase Pyr_redox PF00070.27 KKK17152.1 - 0.015 15.9 0.4 0.075 13.6 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KKK17152.1 - 0.022 13.9 1.0 0.24 10.4 1.0 2.3 1 1 0 1 1 1 0 FAD binding domain MCRA PF06100.11 KKK17152.1 - 0.09 11.5 0.1 0.14 10.9 0.1 1.2 1 0 0 1 1 1 0 MCRA family Amino_oxidase PF01593.24 KKK17152.1 - 0.11 11.7 0.1 2.1 7.6 0.1 2.3 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Thi4 PF01946.17 KKK17152.1 - 0.13 11.5 0.2 0.22 10.7 0.2 1.3 1 0 0 1 1 1 0 Thi4 family CRT10 PF08728.10 KKK17153.1 - 1.2e-22 79.9 0.0 1.2e-13 50.2 0.0 2.3 2 0 0 2 2 2 2 CRT10 SR-25 PF10500.9 KKK17153.1 - 4.3 6.9 11.7 7.9 6.0 11.7 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Pex14_N PF04695.13 KKK17153.1 - 6.7 7.4 15.5 1.2 9.7 8.2 2.8 2 1 1 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PTPLA PF04387.14 KKK17158.1 - 2.4e-56 190.0 2.2 3.7e-56 189.4 2.2 1.3 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA Adaptin_binding PF10199.9 KKK17159.1 - 1e-18 68.1 5.6 1e-18 68.1 5.6 2.3 2 1 0 2 2 2 1 Alpha and gamma adaptin binding protein p34 Nop16 PF09420.10 KKK17159.1 - 0.0012 19.0 1.7 0.002 18.2 1.7 1.3 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 MOR2-PAG1_N PF14222.6 KKK17188.1 - 5.1e-212 705.7 0.0 7.9e-212 705.1 0.0 1.3 1 0 0 1 1 1 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.6 KKK17188.1 - 3.6e-90 302.2 0.0 1.1e-89 300.7 0.0 1.9 2 0 0 2 2 2 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.6 KKK17188.1 - 8.9e-36 123.0 12.3 1.1e-13 49.9 0.0 4.0 2 1 1 3 3 3 3 Cell morphogenesis central region MMS1_N PF10433.9 KKK17189.1 - 1e-132 443.3 0.0 1.3e-132 442.9 0.0 1.1 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 KKK17189.1 - 8.5e-77 258.6 0.0 8.6e-74 248.7 0.0 3.7 4 0 0 4 4 4 2 CPSF A subunit region FAD_binding_1 PF00667.20 KKK17190.1 - 3.2e-64 216.5 0.0 4.8e-64 216.0 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 KKK17190.1 - 1.5e-34 119.2 2.3 2.9e-34 118.3 2.3 1.5 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 KKK17190.1 - 4.3e-20 72.4 0.0 3.2e-19 69.6 0.0 2.2 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 KKK17190.1 - 0.11 12.7 0.0 0.33 11.2 0.0 1.8 1 0 0 1 1 1 0 Flavodoxin domain CENP-S PF15630.6 KKK17191.1 - 2.6e-34 117.4 0.0 3.2e-34 117.1 0.0 1.1 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 KKK17191.1 - 4.5e-09 36.4 0.0 5.1e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Bromo_TP PF07524.13 KKK17191.1 - 0.022 14.7 0.0 0.031 14.3 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated HAUS2 PF15003.6 KKK17191.1 - 0.023 14.4 0.1 0.025 14.3 0.1 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 2 TAF PF02969.17 KKK17191.1 - 0.11 12.7 0.0 0.22 11.7 0.0 1.6 1 1 0 1 1 1 0 TATA box binding protein associated factor (TAF) PGA2 PF07543.12 KKK17192.1 - 1.9e-49 167.2 4.0 2.3e-49 166.9 4.0 1.1 1 0 0 1 1 1 1 Protein trafficking PGA2 EST1 PF10374.9 KKK17192.1 - 0.019 15.6 1.2 0.066 13.8 1.1 1.9 1 1 1 2 2 2 0 Telomerase activating protein Est1 SelK_SelG PF10961.8 KKK17192.1 - 0.32 11.6 1.5 5.7 7.6 0.9 2.4 1 1 1 2 2 2 0 Selenoprotein SelK_SelG Topoisom_I_N PF02919.15 KKK17192.1 - 0.75 9.3 5.6 0.28 10.7 0.7 2.0 2 0 0 2 2 2 0 Eukaryotic DNA topoisomerase I, DNA binding fragment AP3D1 PF06375.11 KKK17192.1 - 2.5 8.3 11.1 0.22 11.7 1.2 2.1 1 1 1 2 2 2 0 AP-3 complex subunit delta-1 MAS20 PF02064.15 KKK17192.1 - 8.7 6.4 8.2 5.8 7.0 1.8 2.3 2 0 0 2 2 2 0 MAS20 protein import receptor MARVEL PF01284.23 KKK17193.1 - 0.0034 17.4 18.2 0.0082 16.2 18.5 1.5 1 1 0 1 1 1 1 Membrane-associating domain Saf_2TM PF18303.1 KKK17193.1 - 0.055 13.1 0.2 0.11 12.1 0.2 1.6 1 1 0 1 1 1 0 SAVED-fused 2TM effector domain DUF2207 PF09972.9 KKK17193.1 - 0.68 8.6 6.9 2.2 7.0 0.0 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) SUR7 PF06687.12 KKK17193.1 - 4 7.0 11.3 0.27 10.8 0.7 2.2 1 1 1 2 2 2 0 SUR7/PalI family CPSase_L_D2 PF02786.17 KKK17194.1 - 1e-74 250.6 0.0 1.5e-74 250.1 0.0 1.2 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.19 KKK17194.1 - 1.2e-36 125.1 0.0 2.5e-36 124.0 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_carb_N PF00289.22 KKK17194.1 - 2.8e-35 121.2 0.0 5.7e-35 120.2 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_lipoyl PF00364.22 KKK17194.1 - 1.5e-14 53.5 2.8 1.8e-13 50.1 2.0 2.8 2 0 0 2 2 2 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 KKK17194.1 - 2.3e-10 40.4 0.0 4.9e-10 39.3 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 KKK17194.1 - 9.2e-09 35.1 0.0 1.7e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 KKK17194.1 - 0.00011 22.3 0.0 0.00024 21.2 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 KKK17194.1 - 0.002 17.9 0.1 0.0038 17.0 0.1 1.5 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATPgrasp_ST PF14397.6 KKK17194.1 - 0.003 16.8 0.0 0.0058 15.9 0.0 1.4 1 0 0 1 1 1 1 Sugar-transfer associated ATP-grasp Biotin_lipoyl_2 PF13533.6 KKK17194.1 - 0.0083 15.9 0.2 0.056 13.3 0.1 2.5 1 1 1 2 2 2 1 Biotin-lipoyl like ATP-grasp_4 PF13535.6 KKK17194.1 - 0.042 13.5 0.0 0.085 12.4 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain GCV_H PF01597.19 KKK17194.1 - 0.043 13.7 0.1 0.1 12.5 0.1 1.6 1 0 0 1 1 1 0 Glycine cleavage H-protein RimK PF08443.11 KKK17194.1 - 0.073 12.7 0.0 0.23 11.1 0.0 1.7 2 0 0 2 2 2 0 RimK-like ATP-grasp domain RelA_SpoT PF04607.17 KKK17194.1 - 0.17 12.2 0.0 2.3 8.6 0.0 2.4 2 0 0 2 2 2 0 Region found in RelA / SpoT proteins DUF963 PF06131.11 KKK17195.1 - 0.14 11.6 6.9 2.6 7.5 2.1 2.9 2 0 0 2 2 2 0 Schizosaccharomyces pombe repeat of unknown function (DUF963) Acyl-CoA_dh_1 PF00441.24 KKK17196.1 - 1.6e-39 135.5 0.8 2.8e-39 134.7 0.8 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KKK17196.1 - 1.7e-32 112.4 0.1 3.2e-32 111.6 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KKK17196.1 - 1.2e-24 86.3 0.1 2.4e-24 85.4 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KKK17196.1 - 2.9e-13 50.2 0.1 5.8e-13 49.3 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 KKK17196.1 - 0.062 13.0 0.1 0.22 11.1 0.1 1.8 1 1 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal Sulfotransfer_3 PF13469.6 KKK17197.1 - 0.0042 17.5 0.1 0.014 15.8 0.1 1.8 1 1 0 1 1 1 1 Sulfotransferase family Carboxyl_trans PF01039.22 KKK17198.1 - 7.3e-139 463.6 0.2 9.2e-139 463.3 0.2 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain adh_short_C2 PF13561.6 KKK17198.1 - 0.068 12.7 0.4 0.17 11.4 0.0 1.7 2 0 0 2 2 2 0 Enoyl-(Acyl carrier protein) reductase ketoacyl-synt PF00109.26 KKK17199.1 - 1e-72 244.8 0.0 2.5e-72 243.5 0.0 1.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain SAT PF16073.5 KKK17199.1 - 2.1e-44 152.1 0.0 1.1e-43 149.7 0.0 2.1 2 0 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Ketoacyl-synt_C PF02801.22 KKK17199.1 - 6.5e-36 122.9 3.2 2.7e-35 120.9 1.0 2.4 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.21 KKK17199.1 - 3.1e-32 112.4 0.1 5.5e-32 111.5 0.1 1.4 1 0 0 1 1 1 1 Acyl transferase domain KAsynt_C_assoc PF16197.5 KKK17199.1 - 1.8e-10 41.3 0.0 4.5e-10 40.0 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension PP-binding PF00550.25 KKK17199.1 - 1.2e-08 35.2 0.3 3.3e-08 33.8 0.3 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.23 KKK17199.1 - 0.028 13.8 0.3 0.059 12.7 0.3 1.4 1 0 0 1 1 1 0 Thiolase, N-terminal domain Raf1_HTH PF18579.1 KKK17199.1 - 0.064 12.9 0.0 0.21 11.3 0.0 1.9 1 0 0 1 1 1 0 Rubisco accumulation factor 1 helix turn helix domain Methyltransf_2 PF00891.18 KKK17200.1 - 5.5e-20 71.6 0.0 1e-19 70.7 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation2 PF16864.5 KKK17200.1 - 0.0057 16.6 0.0 0.015 15.3 0.0 1.7 1 0 0 1 1 1 1 Dimerisation domain Dimerisation PF08100.11 KKK17200.1 - 0.029 14.4 0.1 0.067 13.2 0.1 1.6 1 0 0 1 1 1 0 Dimerisation domain p450 PF00067.22 KKK17201.1 - 2e-22 79.6 0.1 2.8e-22 79.1 0.1 1.2 1 0 0 1 1 1 1 Cytochrome P450 DUF3991 PF13154.6 KKK17201.1 - 0.1 13.0 0.0 0.35 11.3 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3991) DUF4980 PF16352.5 KKK17201.1 - 0.12 12.4 0.1 0.4 10.7 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4980) Velvet PF11754.8 KKK17202.1 - 1.7e-89 300.0 0.0 2.2e-89 299.7 0.0 1.0 1 0 0 1 1 1 1 Velvet factor Ribosomal_L13 PF00572.18 KKK17204.1 - 1.3e-36 125.5 0.0 1.5e-36 125.4 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L13 OTU PF02338.19 KKK17205.1 - 5e-08 33.5 0.0 8.5e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C12 PF01088.21 KKK17206.1 - 6.2e-62 209.1 0.0 8.6e-62 208.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 KKK17206.1 - 0.021 14.7 0.4 0.058 13.3 0.0 1.9 2 0 0 2 2 2 0 Ubiquitin carboxyl-terminal hydrolases I-set PF07679.16 KKK17207.1 - 0.012 15.7 0.2 1.6 8.9 0.0 4.0 5 0 0 5 5 5 0 Immunoglobulin I-set domain Oxysterol_BP PF01237.18 KKK17208.1 - 2.2e-48 165.0 0.1 4.6e-42 144.2 0.0 2.1 1 1 1 2 2 2 2 Oxysterol-binding protein Cys_Met_Meta_PP PF01053.20 KKK17209.1 - 2.5e-31 108.6 0.0 3.1e-31 108.3 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Nrap_D4 PF17405.2 KKK17210.1 - 5.8e-63 212.1 0.0 9.5e-63 211.4 0.0 1.3 1 0 0 1 1 1 1 Nrap protein nucleotidyltransferase domain 4 Nrap_D5 PF17406.2 KKK17210.1 - 3.6e-56 189.4 0.0 6.8e-56 188.5 0.0 1.5 1 0 0 1 1 1 1 Nrap protein PAP/OAS1-like domain 5 Nrap_D2 PF17403.2 KKK17210.1 - 4.4e-50 169.4 0.0 1.3e-47 161.4 0.0 2.5 2 0 0 2 2 2 2 Nrap protein PAP/OAS-like domain Nrap_D3 PF17404.2 KKK17210.1 - 2.9e-45 154.2 0.0 5.9e-45 153.2 0.0 1.5 1 0 0 1 1 1 1 Nrap protein domain 3 Nrap PF03813.14 KKK17210.1 - 9.7e-44 149.1 0.0 1.9e-43 148.1 0.0 1.5 1 0 0 1 1 1 1 Nrap protein domain 1 Nrap_D6 PF17407.2 KKK17210.1 - 3.4e-30 105.0 0.0 7.4e-30 103.9 0.0 1.6 1 0 0 1 1 1 1 Nrap protein domain 6 PAP_central PF04928.17 KKK17210.1 - 0.011 14.7 0.0 0.073 12.0 0.1 2.1 2 0 0 2 2 2 0 Poly(A) polymerase central domain MRP-L20 PF12824.7 KKK17211.1 - 2e-64 216.7 8.4 2.2e-64 216.5 8.4 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Mito_carr PF00153.27 KKK17212.1 - 2.7e-51 171.5 3.8 8.7e-22 76.9 0.1 4.0 4 0 0 4 4 4 4 Mitochondrial carrier protein DEAD PF00270.29 KKK17213.1 - 5.3e-42 143.6 0.0 7.5e-42 143.1 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KKK17213.1 - 5.1e-28 97.6 0.7 7.7e-27 93.8 0.5 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KKK17213.1 - 0.012 15.7 0.0 0.024 14.6 0.0 1.5 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Peptidase_M20 PF01546.28 KKK17214.1 - 2.2e-31 109.2 0.0 2.8e-31 108.9 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KKK17214.1 - 1.8e-12 47.1 0.0 3.3e-12 46.3 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KKK17214.1 - 0.024 14.3 0.0 0.047 13.4 0.0 1.5 1 0 0 1 1 1 0 Peptidase family M28 PCRF PF03462.18 KKK17215.1 - 3e-51 174.0 0.0 2.9e-50 170.9 0.0 2.0 2 0 0 2 2 2 1 PCRF domain RF-1 PF00472.20 KKK17215.1 - 1.2e-34 118.7 1.4 1.2e-34 118.7 1.4 2.1 2 0 0 2 2 2 1 RF-1 domain Syntaxin_2 PF14523.6 KKK17215.1 - 0.045 14.1 2.2 0.057 13.8 0.3 2.0 2 0 0 2 2 2 0 Syntaxin-like protein Pas_Saposin PF09016.10 KKK17215.1 - 0.14 12.5 0.0 0.29 11.5 0.0 1.5 1 0 0 1 1 1 0 Pas factor saposin fold BST2 PF16716.5 KKK17215.1 - 0.53 10.9 4.1 1.1 9.8 0.6 2.4 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 Cnd1_N PF12922.7 KKK17217.1 - 1.2e-61 207.4 0.1 2.6e-61 206.3 0.1 1.6 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1, N-term Cnd1 PF12717.7 KKK17217.1 - 4.1e-47 160.2 2.9 6.4e-42 143.4 0.1 3.3 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KKK17217.1 - 9e-10 38.0 7.0 0.054 13.8 0.0 6.2 5 0 0 5 5 5 4 HEAT repeat HEAT_2 PF13646.6 KKK17217.1 - 1.4e-09 38.2 8.3 2.8e-05 24.4 0.0 4.3 5 0 0 5 5 5 2 HEAT repeats Adaptin_N PF01602.20 KKK17217.1 - 7.7e-07 28.0 7.1 0.028 13.0 0.2 4.1 3 2 0 3 3 3 3 Adaptin N terminal region HEAT_EZ PF13513.6 KKK17217.1 - 3.6e-05 24.1 10.1 0.78 10.3 0.1 6.2 6 0 0 6 6 6 2 HEAT-like repeat RTP1_C1 PF10363.9 KKK17217.1 - 0.00013 22.1 0.1 0.2 11.8 0.0 3.4 2 1 0 2 2 2 2 Required for nuclear transport of RNA pol II C-terminus 1 Cnd3 PF12719.7 KKK17217.1 - 0.00018 20.8 2.6 0.00065 19.0 0.4 2.9 3 1 0 3 3 3 1 Nuclear condensing complex subunits, C-term domain Pkinase PF00069.25 KKK17218.1 - 8.5e-42 143.3 0.0 5.3e-19 68.6 0.0 3.1 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 KKK17218.1 - 2.4e-09 36.9 0.0 0.00057 19.2 0.0 3.1 2 1 1 3 3 3 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 KKK17218.1 - 0.013 14.3 0.0 0.022 13.6 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 KKK17218.1 - 0.022 14.7 0.3 0.97 9.3 0.1 2.4 2 1 1 3 3 3 0 Phosphotransferase enzyme family FTA2 PF13095.6 KKK17218.1 - 0.027 14.1 0.0 0.13 11.9 0.0 2.0 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Bromodomain PF00439.25 KKK17219.1 - 4.6e-38 129.2 4.6 1.9e-20 72.7 0.3 2.5 2 0 0 2 2 2 2 Bromodomain BAH PF01426.18 KKK17219.1 - 6.1e-19 68.1 1.3 1.3e-18 67.0 1.3 1.6 1 0 0 1 1 1 1 BAH domain CDC45 PF02724.14 KKK17219.1 - 0.0013 17.1 6.1 0.0013 17.1 6.1 2.0 2 0 0 2 2 2 1 CDC45-like protein HHH_6 PF14579.6 KKK17219.1 - 0.07 13.4 0.1 12 6.2 0.0 2.8 2 0 0 2 2 2 0 Helix-hairpin-helix motif CENP-B_dimeris PF09026.10 KKK17219.1 - 0.66 10.4 11.9 2.1 8.8 11.9 1.8 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Stathmin PF00836.19 KKK17219.1 - 2.5 8.1 12.1 3.8 7.5 11.1 1.8 1 1 0 1 1 1 0 Stathmin family HTH_32 PF13565.6 KKK17219.1 - 4.6 7.9 11.3 1.4 9.6 1.2 3.6 3 1 0 3 3 3 0 Homeodomain-like domain SMC_N PF02463.19 KKK17220.1 - 4.3e-21 75.4 18.9 1.3e-12 47.6 0.2 3.1 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KKK17220.1 - 1.4e-14 55.1 21.8 1.4e-14 55.1 21.8 5.0 2 2 1 3 3 3 1 AAA domain AAA_15 PF13175.6 KKK17220.1 - 1.8e-07 31.2 18.0 1.8e-07 31.2 18.0 3.5 2 2 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 KKK17220.1 - 5.2e-07 29.8 6.8 7.2e-05 22.7 0.4 3.6 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system Spc7 PF08317.11 KKK17220.1 - 4.9e-06 25.7 19.4 4.9e-06 25.7 19.4 4.7 2 2 2 4 4 4 2 Spc7 kinetochore protein AAA_29 PF13555.6 KKK17220.1 - 0.00012 21.8 0.0 0.00025 20.7 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain YabA PF06156.13 KKK17220.1 - 0.015 15.9 6.8 0.015 15.9 6.8 6.4 4 2 2 6 6 6 0 Initiation control protein YabA SMC_hinge PF06470.13 KKK17220.1 - 0.035 14.4 0.0 0.2 12.0 0.0 2.4 2 0 0 2 2 2 0 SMC proteins Flexible Hinge Domain ABC_tran PF00005.27 KKK17220.1 - 0.12 12.8 0.1 0.12 12.8 0.1 6.1 3 2 0 3 3 3 0 ABC transporter Fungal_trans PF04082.18 KKK17221.1 - 7.3e-09 35.0 0.7 9.6e-08 31.4 0.7 2.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK17221.1 - 0.0017 18.4 13.3 0.022 14.9 13.3 2.3 1 1 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.12 KKK17221.1 - 5.4 7.6 8.1 13 6.3 1.1 2.3 2 0 0 2 2 2 0 Dickkopf N-terminal cysteine-rich region Acetyltransf_1 PF00583.25 KKK17222.1 - 2e-10 40.9 0.0 3e-10 40.3 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KKK17222.1 - 5.1e-09 36.1 0.0 8.5e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KKK17222.1 - 8.8e-08 32.5 0.0 1.5e-07 31.7 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KKK17222.1 - 0.045 13.8 0.0 0.092 12.8 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KKK17222.1 - 0.11 12.6 0.0 0.33 11.1 0.0 1.8 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase Metallophos PF00149.28 KKK17223.1 - 3.3e-32 112.6 0.0 1.6e-22 81.0 0.0 2.2 1 1 1 2 2 2 2 Calcineurin-like phosphoesterase COA2 PF17051.5 KKK17224.1 - 0.014 15.4 0.0 0.021 14.9 0.0 1.3 1 0 0 1 1 1 0 Cytochrome C oxidase assembly factor 2 ALG3 PF05208.13 KKK17225.1 - 1.3e-142 475.5 11.3 1.5e-142 475.3 11.3 1.0 1 0 0 1 1 1 1 ALG3 protein eIF-1a PF01176.19 KKK17226.1 - 1.5e-16 59.9 0.0 2e-16 59.5 0.0 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 GnsAB_toxin PF08178.11 KKK17226.1 - 0.0088 15.9 0.0 0.015 15.2 0.0 1.3 1 0 0 1 1 1 1 GnsA/GnsB toxin of bacterial toxin-antitoxin system Zn_clus PF00172.18 KKK17227.1 - 9.9e-09 35.2 12.1 2.1e-08 34.1 12.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KKK17228.1 - 1.1e-08 34.4 2.9 1.7e-08 33.8 2.4 1.5 1 1 1 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK17228.1 - 0.019 15.1 0.7 0.038 14.1 0.7 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Terpene_synth_C PF03936.16 KKK17229.1 - 1.2e-06 28.1 4.7 2.1e-05 24.0 0.2 2.2 2 0 0 2 2 2 2 Terpene synthase family, metal binding domain YfbU PF03887.14 KKK17229.1 - 0.08 12.9 0.1 0.37 10.8 0.0 2.0 2 0 0 2 2 2 0 YfbU domain adh_short PF00106.25 KKK17231.1 - 1.3e-24 86.7 0.0 9.7e-24 83.9 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KKK17231.1 - 7.9e-14 51.8 0.0 2.7e-13 50.0 0.0 1.8 2 1 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 KKK17231.1 - 0.0016 18.0 0.1 0.0031 17.0 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KKK17231.1 - 0.0056 16.6 0.1 0.011 15.6 0.1 1.4 1 0 0 1 1 1 1 KR domain ATP-synt_F PF01990.17 KKK17231.1 - 0.032 14.6 0.0 0.064 13.6 0.0 1.4 1 0 0 1 1 1 0 ATP synthase (F/14-kDa) subunit MFS_1 PF07690.16 KKK17232.1 - 1.3e-36 126.3 56.3 8.8e-25 87.4 22.8 3.0 3 0 0 3 3 3 2 Major Facilitator Superfamily DUF4501 PF14946.6 KKK17232.1 - 0.044 13.8 0.1 0.095 12.8 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4501) Trp_oprn_chp PF09534.10 KKK17232.1 - 0.12 12.2 2.8 0.37 10.6 0.2 2.5 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) CrgA PF06781.12 KKK17232.1 - 0.3 11.2 4.5 0.45 10.6 0.0 3.1 3 0 0 3 3 3 0 Cell division protein CrgA FMN_red PF03358.15 KKK17233.1 - 1.6e-29 102.6 0.0 2.1e-29 102.3 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 KKK17233.1 - 3.3e-07 30.2 0.0 4.3e-07 29.8 0.0 1.3 1 1 0 1 1 1 1 Flavodoxin-like fold DUF1604 PF07713.13 KKK17269.1 - 2.2e-43 145.9 3.2 5.6e-43 144.7 1.2 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1604) G-patch PF01585.23 KKK17269.1 - 6.4e-08 32.4 1.2 1.5e-07 31.1 1.2 1.7 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 KKK17269.1 - 0.034 14.2 1.7 0.14 12.2 0.4 2.7 1 1 1 2 2 2 0 G-patch domain UBD PF16455.5 KKK17270.1 - 2.9e-41 139.9 0.0 4.2e-41 139.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-binding domain ubiquitin PF00240.23 KKK17270.1 - 7.4e-06 25.6 0.0 1.1e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family Med26_C PF15693.5 KKK17270.1 - 0.065 13.4 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 Mediator complex subunit 26 C-terminal DUF2407 PF10302.9 KKK17270.1 - 0.1 13.2 0.0 0.25 11.9 0.0 1.6 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain ABC2_membrane PF01061.24 KKK17271.1 - 1.1e-88 296.2 53.2 3.1e-44 150.9 24.5 2.5 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 KKK17271.1 - 5.7e-36 124.1 0.1 1.2e-17 64.7 0.0 3.0 3 0 0 3 3 3 2 ABC transporter PDR_CDR PF06422.12 KKK17271.1 - 9.1e-33 112.0 2.3 2.6e-30 104.2 0.1 3.9 4 0 0 4 4 3 2 CDR ABC transporter ABC_trans_N PF14510.6 KKK17271.1 - 3e-17 63.0 0.0 9e-17 61.5 0.0 1.9 1 0 0 1 1 1 1 ABC-transporter N-terminal ABC2_membrane_3 PF12698.7 KKK17271.1 - 1.9e-07 30.5 43.9 0.00071 18.8 20.2 2.5 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_25 PF13481.6 KKK17271.1 - 1.1e-05 25.2 0.1 0.0015 18.1 0.1 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KKK17271.1 - 3.3e-05 24.3 0.1 0.0057 17.1 0.0 2.7 2 1 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 KKK17271.1 - 3.9e-05 23.6 0.0 0.0065 16.4 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_33 PF13671.6 KKK17271.1 - 6.9e-05 23.0 0.0 0.18 11.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 KKK17271.1 - 0.00018 22.1 0.0 0.0044 17.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KKK17271.1 - 0.001 18.8 1.8 0.061 13.1 0.1 3.1 3 0 0 3 3 3 1 P-loop containing region of AAA domain cobW PF02492.19 KKK17271.1 - 0.0074 15.9 1.2 0.092 12.3 0.1 2.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 KKK17271.1 - 0.011 15.6 2.0 3.7 7.4 0.2 2.9 3 0 0 3 3 3 0 NACHT domain SMC_N PF02463.19 KKK17271.1 - 0.013 14.9 0.1 0.94 8.9 0.0 3.2 3 1 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KKK17271.1 - 0.014 15.6 0.2 1.3 9.2 0.0 2.9 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 KKK17271.1 - 0.016 15.3 0.1 6.7 6.8 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase RNA_helicase PF00910.22 KKK17271.1 - 0.017 15.5 0.2 4.4 7.8 0.1 2.7 2 0 0 2 2 2 0 RNA helicase AAA_30 PF13604.6 KKK17271.1 - 0.021 14.5 1.2 0.43 10.3 0.2 2.6 3 0 0 3 3 3 0 AAA domain AAA_17 PF13207.6 KKK17271.1 - 0.029 14.8 0.1 0.4 11.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.6 KKK17271.1 - 0.033 14.0 2.6 2 8.2 0.0 3.4 4 0 0 4 4 3 0 AAA domain, putative AbiEii toxin, Type IV TA system dNK PF01712.19 KKK17271.1 - 0.12 12.2 0.0 4.5 7.1 0.0 2.5 2 0 0 2 2 2 0 Deoxynucleoside kinase AAA PF00004.29 KKK17271.1 - 0.17 12.3 0.1 13 6.2 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Nop52 PF05997.12 KKK17272.1 - 3.7e-53 180.5 0.3 2.1e-39 135.5 0.3 2.2 2 0 0 2 2 2 2 Nucleolar protein,Nop52 FancD2 PF14631.6 KKK17272.1 - 0.015 12.8 0.7 0.019 12.4 0.7 1.1 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease RNA_pol_Rpc82 PF05645.13 KKK17272.1 - 0.015 15.1 0.1 0.026 14.3 0.1 1.3 1 0 0 1 1 1 0 RNA polymerase III subunit RPC82 RNA_pol_Rpc4 PF05132.14 KKK17272.1 - 0.016 15.6 0.2 0.031 14.7 0.2 1.5 1 0 0 1 1 1 0 RNA polymerase III RPC4 DUF4228 PF14009.6 KKK17272.1 - 0.018 15.4 0.4 0.037 14.4 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) NARP1 PF12569.8 KKK17272.1 - 0.025 13.5 2.2 0.038 12.9 2.2 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 FAM181 PF15238.6 KKK17272.1 - 0.061 13.2 2.9 0.1 12.4 2.9 1.3 1 0 0 1 1 1 0 FAM181 HTH_IclR PF09339.10 KKK17272.1 - 0.074 12.9 0.1 0.39 10.5 0.1 2.2 1 1 0 1 1 1 0 IclR helix-turn-helix domain Presenilin PF01080.17 KKK17272.1 - 0.12 11.1 2.2 0.16 10.7 2.2 1.2 1 0 0 1 1 1 0 Presenilin NOT2_3_5 PF04153.18 KKK17272.1 - 0.16 12.1 0.1 0.16 12.1 0.1 2.0 2 0 0 2 2 2 0 NOT2 / NOT3 / NOT5 family NPR3 PF03666.13 KKK17272.1 - 0.57 8.9 4.5 0.82 8.4 4.5 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 MCM_bind PF09739.9 KKK17272.1 - 0.94 7.8 3.6 1.3 7.3 3.6 1.2 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor DUF4820 PF16091.5 KKK17272.1 - 3.3 7.0 6.8 0.52 9.6 2.6 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) PBP1_TM PF14812.6 KKK17272.1 - 4.6 7.7 12.7 0.087 13.2 1.2 2.9 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Transp_cyt_pur PF02133.15 KKK17278.1 - 1e-90 304.6 43.2 1.2e-90 304.4 43.2 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Pkinase PF00069.25 KKK17279.1 - 5.7e-14 52.1 0.2 4.2e-12 46.0 0.2 2.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK17279.1 - 0.0044 16.4 0.1 0.07 12.4 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase DUF4116 PF13475.6 KKK17279.1 - 0.17 11.6 0.3 2.3 8.0 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4116) Pyrid_oxidase_2 PF13883.6 KKK17280.1 - 1.9e-36 125.6 0.0 2.5e-36 125.2 0.0 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Cyclin PF08613.11 KKK17281.1 - 6.8e-07 29.8 0.6 7.2e-06 26.5 0.0 2.4 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.23 KKK17281.1 - 0.0017 18.1 0.1 0.0036 17.0 0.1 1.6 1 1 0 1 1 1 1 Cyclin, N-terminal domain Sugar_tr PF00083.24 KKK17282.1 - 8.6e-88 295.2 22.0 1e-87 294.9 22.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKK17282.1 - 4.2e-21 75.3 47.7 3.6e-16 59.0 20.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KKK17282.1 - 0.54 8.5 15.6 0.26 9.5 2.0 3.4 1 1 2 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family DUF3100 PF11299.8 KKK17282.1 - 1.8 7.9 8.2 1.6 8.1 0.8 3.1 2 1 0 3 3 3 0 Protein of unknown function (DUF3100) zf-C2H2 PF00096.26 KKK17283.1 - 9.2e-10 38.4 7.2 2e-07 31.1 0.3 3.1 2 1 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KKK17283.1 - 0.00014 22.4 7.6 0.00019 22.0 0.2 3.1 3 0 0 3 3 3 1 C2H2-type zinc finger zf-met PF12874.7 KKK17283.1 - 0.022 15.2 0.0 0.12 12.8 0.0 2.1 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 KKK17283.1 - 0.023 14.5 0.0 0.06 13.1 0.0 1.6 1 0 0 1 1 1 0 zinc-finger C2H2-type zf-H2C2_2 PF13465.6 KKK17283.1 - 0.043 14.3 0.8 0.043 14.3 0.8 3.4 3 0 0 3 3 3 0 Zinc-finger double domain Methyltransf_13 PF08421.11 KKK17283.1 - 0.14 12.5 0.4 0.32 11.3 0.4 1.7 1 1 0 1 1 1 0 Putative zinc binding domain zf-LYAR PF08790.11 KKK17283.1 - 0.15 12.0 0.2 0.26 11.2 0.2 1.4 1 0 0 1 1 1 0 LYAR-type C2HC zinc finger SecE PF00584.20 KKK17285.1 - 6.9e-13 48.3 0.0 8.3e-13 48.1 0.0 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex Pyr_redox_2 PF07992.14 KKK17286.1 - 6e-72 242.3 6.6 6e-72 242.3 6.6 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 KKK17286.1 - 1.1e-40 138.2 0.2 3.5e-40 136.7 0.2 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 KKK17286.1 - 8.6e-22 77.5 9.0 1.4e-20 73.6 0.7 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KKK17286.1 - 8.6e-11 41.9 4.5 3.7e-06 27.1 0.5 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 KKK17286.1 - 5.4e-10 39.2 12.1 1e-09 38.3 0.4 3.0 2 1 1 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KKK17286.1 - 1.1e-09 38.0 4.9 1.4e-07 31.1 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KKK17286.1 - 4e-09 36.0 14.0 9.3e-08 31.5 4.3 3.2 2 2 1 3 3 3 2 Glucose inhibited division protein A DAO PF01266.24 KKK17286.1 - 1.2e-07 31.7 13.0 0.0083 15.8 0.5 4.2 4 0 0 4 4 4 3 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 KKK17286.1 - 2.7e-07 30.1 8.3 0.00072 18.9 0.7 3.6 3 1 0 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 KKK17286.1 - 4.3e-07 29.4 2.0 4.3e-07 29.4 2.0 2.6 2 1 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 KKK17286.1 - 5.8e-06 25.3 14.6 0.00039 19.2 1.5 4.1 4 0 0 4 4 4 2 HI0933-like protein K_oxygenase PF13434.6 KKK17286.1 - 5.9e-06 25.7 1.1 0.073 12.2 0.0 2.9 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 KKK17286.1 - 1.9e-05 24.0 3.7 0.00045 19.5 0.1 2.4 2 0 0 2 2 2 1 Thi4 family Lycopene_cycl PF05834.12 KKK17286.1 - 0.00098 18.3 1.8 0.15 11.1 0.0 2.7 2 1 0 2 2 2 2 Lycopene cyclase protein THF_DHG_CYH_C PF02882.19 KKK17286.1 - 0.002 17.5 1.1 0.19 11.0 0.0 3.9 3 2 1 4 4 4 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain FAD_binding_3 PF01494.19 KKK17286.1 - 0.0058 15.9 10.3 0.31 10.2 0.6 3.0 2 1 0 2 2 2 2 FAD binding domain 3HCDH_N PF02737.18 KKK17286.1 - 0.024 14.5 4.5 0.032 14.1 1.3 2.5 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 KKK17286.1 - 0.12 12.9 3.7 0.16 12.4 0.1 2.8 4 0 0 4 4 3 0 Putative NAD(P)-binding FMO-like PF00743.19 KKK17286.1 - 0.12 10.8 2.8 3.3 6.0 0.7 2.8 3 0 0 3 3 3 0 Flavin-binding monooxygenase-like Trp_halogenase PF04820.14 KKK17286.1 - 0.13 11.1 5.6 0.32 9.8 0.5 2.3 2 0 0 2 2 2 0 Tryptophan halogenase UDPG_MGDP_dh_N PF03721.14 KKK17286.1 - 6.4 6.3 7.1 1.8 8.1 0.5 2.8 3 0 0 3 3 3 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain PGM_PMM_I PF02878.16 KKK17287.1 - 6.4e-34 116.6 0.0 1.3e-33 115.7 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 KKK17287.1 - 5.6e-24 84.7 0.0 1.7e-23 83.1 0.0 1.9 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 KKK17287.1 - 1.3e-15 57.6 0.0 2.5e-15 56.7 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.20 KKK17287.1 - 1.9e-06 28.0 0.0 5.9e-06 26.4 0.0 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain KHA PF11834.8 KKK17288.1 - 0.17 12.0 0.0 0.65 10.1 0.0 1.9 1 1 1 2 2 2 0 KHA, dimerisation domain of potassium ion channel DUF2120 PF09893.9 KKK17289.1 - 0.029 14.5 0.1 0.041 14.0 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2120) CBF PF03914.17 KKK17290.1 - 1.1e-37 129.6 0.2 2.3e-37 128.6 0.2 1.6 1 0 0 1 1 1 1 CBF/Mak21 family Titin_Ig-rpts PF06582.12 KKK17290.1 - 0.062 13.2 0.6 0.14 12.1 0.6 1.5 1 0 0 1 1 1 0 Titin repeat Mt_ATP-synt_B PF05405.14 KKK17291.1 - 2e-52 177.1 8.3 3e-52 176.5 8.3 1.3 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Sel1 PF08238.12 KKK17291.1 - 7.1e-14 51.9 0.1 1.8e-05 25.3 0.0 3.8 4 0 0 4 4 4 3 Sel1 repeat V_ATPase_I PF01496.19 KKK17291.1 - 0.18 9.7 3.1 0.25 9.2 3.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PCI PF01399.27 KKK17292.1 - 2.2e-11 44.2 0.0 4.7e-11 43.1 0.0 1.6 1 0 0 1 1 1 1 PCI domain RPN7 PF10602.9 KKK17292.1 - 4.1e-09 36.4 0.6 7.5e-09 35.5 0.6 1.4 1 0 0 1 1 1 1 26S proteasome subunit RPN7 TPR_19 PF14559.6 KKK17292.1 - 0.0018 18.7 1.2 0.052 14.1 0.2 3.0 1 1 1 2 2 2 2 Tetratricopeptide repeat Herpes_UL14 PF03580.14 KKK17292.1 - 0.0079 16.5 4.4 0.29 11.4 0.7 2.6 1 1 1 2 2 2 2 Herpesvirus UL14-like protein DUF5578 PF17741.1 KKK17292.1 - 0.038 13.4 1.0 0.069 12.6 0.5 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5578) FAD_binding_2 PF00890.24 KKK17293.1 - 1.6e-84 284.5 1.3 1.9e-84 284.2 1.3 1.1 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.28 KKK17293.1 - 5.4e-21 74.5 0.0 2.1e-19 69.4 0.0 2.8 3 0 0 3 3 3 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.24 KKK17293.1 - 2.8e-13 50.2 0.3 5.2e-13 49.3 0.3 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 KKK17293.1 - 1.7e-09 37.5 0.9 7.8e-09 35.4 0.9 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KKK17293.1 - 1.7e-07 31.4 2.5 8.7e-07 29.1 0.4 3.1 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KKK17293.1 - 6.3e-07 28.9 0.7 1.7e-05 24.2 0.6 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KKK17293.1 - 2e-06 26.8 5.2 0.0025 16.6 0.3 3.2 3 0 0 3 3 3 2 HI0933-like protein Pyr_redox_3 PF13738.6 KKK17293.1 - 5.8e-06 25.8 0.0 0.022 14.0 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KKK17293.1 - 0.00011 21.6 0.1 0.00019 20.8 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 KKK17293.1 - 0.00084 18.6 1.2 0.051 12.8 0.5 2.3 2 0 0 2 2 2 1 Thi4 family GIDA PF01134.22 KKK17293.1 - 0.0012 18.0 2.6 0.3 10.1 0.7 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A Amino_oxidase PF01593.24 KKK17293.1 - 0.0017 17.7 0.5 0.92 8.7 0.0 2.9 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 KKK17293.1 - 0.0095 16.5 1.8 6.1 7.5 0.0 2.8 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KKK17293.1 - 0.015 15.3 2.4 0.2 11.6 2.4 2.5 1 1 0 1 1 1 0 FAD-NAD(P)-binding FlgD_ig PF13860.6 KKK17293.1 - 0.12 12.3 0.9 0.28 11.1 0.0 2.0 2 0 0 2 2 2 0 FlgD Ig-like domain bZIP_Maf PF03131.17 KKK17295.1 - 2.9e-07 30.9 10.5 2.9e-07 30.9 10.5 2.3 2 0 0 2 2 2 1 bZIP Maf transcription factor bZIP_1 PF00170.21 KKK17295.1 - 2.9e-07 30.5 20.4 1e-06 28.7 14.9 2.5 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 KKK17295.1 - 4.6e-07 29.8 18.1 2.3e-06 27.6 10.6 2.6 2 0 0 2 2 2 2 Basic region leucine zipper Capsule_synth PF05159.14 KKK17295.1 - 0.022 14.2 0.9 0.044 13.2 0.0 1.8 2 0 0 2 2 2 0 Capsule polysaccharide biosynthesis protein Tho2 PF11262.8 KKK17295.1 - 4.9 6.3 14.6 1.8 7.7 11.9 1.5 1 1 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 DUF745 PF05335.13 KKK17295.1 - 6.7 6.4 11.1 21 4.8 11.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF745) zf-CCCH PF00642.24 KKK17296.1 - 5.9e-13 48.4 30.1 6.7e-06 25.9 1.3 5.3 5 0 0 5 5 5 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KKK17296.1 - 2.1e-08 33.9 28.1 0.047 13.8 0.9 6.0 5 1 0 5 5 5 4 Zinc finger domain zf-CCCH_3 PF15663.5 KKK17296.1 - 0.00034 20.8 17.6 0.0054 16.9 1.4 3.5 2 2 1 3 3 3 2 Zinc-finger containing family zf-C3H1 PF10650.9 KKK17296.1 - 0.00053 19.7 5.1 0.12 12.2 0.0 4.3 4 0 0 4 4 4 1 Putative zinc-finger domain zf-CCCH_4 PF18044.1 KKK17296.1 - 0.0011 18.6 23.3 0.0016 18.2 0.0 5.4 5 1 0 5 5 5 2 CCCH-type zinc finger Torus PF16131.5 KKK17296.1 - 0.012 16.3 26.2 0.34 11.6 0.5 4.8 2 1 3 5 5 5 0 Torus domain zf-CCCH_2 PF14608.6 KKK17296.1 - 0.027 15.0 1.8 0.027 15.0 1.8 4.5 5 0 0 5 5 5 0 RNA-binding, Nab2-type zinc finger WD40 PF00400.32 KKK17298.1 - 4.5e-13 49.5 3.2 0.075 13.9 0.3 6.8 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKK17298.1 - 0.022 15.1 0.1 7 7.0 0.0 3.8 3 2 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Sin3a_C PF16879.5 KKK17299.1 - 2.3e-80 270.4 6.1 2.3e-80 270.4 6.1 2.6 3 0 0 3 3 3 1 C-terminal domain of Sin3a protein PAH PF02671.21 KKK17299.1 - 9.2e-44 147.3 7.4 1.3e-17 63.7 0.0 4.1 4 0 0 4 4 4 3 Paired amphipathic helix repeat Sin3_corepress PF08295.12 KKK17299.1 - 2.7e-39 133.2 1.1 5.1e-39 132.3 0.1 2.0 2 0 0 2 2 2 1 Sin3 family co-repressor ESM4 PF15952.5 KKK17299.1 - 0.098 13.1 3.6 0.37 11.2 3.6 2.0 1 0 0 1 1 1 0 Enhancer of split M4 family SHE3 PF17078.5 KKK17300.1 - 1.5e-11 44.5 26.7 2.9e-11 43.5 26.7 1.5 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 ATG16 PF08614.11 KKK17300.1 - 0.00038 20.7 36.4 0.021 15.1 16.8 3.1 1 1 1 2 2 2 1 Autophagy protein 16 (ATG16) Spc7 PF08317.11 KKK17300.1 - 0.0044 15.9 34.5 0.0076 15.2 15.7 2.1 1 1 1 2 2 2 2 Spc7 kinetochore protein Filament PF00038.21 KKK17300.1 - 0.032 13.8 35.3 2.7 7.5 35.3 2.2 1 1 0 1 1 1 0 Intermediate filament protein ZapB PF06005.12 KKK17300.1 - 0.046 14.2 2.2 0.046 14.2 2.2 4.3 2 1 1 3 3 2 0 Cell division protein ZapB SlyX PF04102.12 KKK17300.1 - 0.048 14.3 19.7 2.3 8.9 0.4 5.4 1 1 3 5 5 5 0 SlyX TPR_MLP1_2 PF07926.12 KKK17300.1 - 0.069 13.2 31.9 0.052 13.6 15.2 2.7 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Jnk-SapK_ap_N PF09744.9 KKK17300.1 - 0.071 13.3 39.4 0.03 14.5 4.7 3.5 1 1 2 3 3 3 0 JNK_SAPK-associated protein-1 DUF812 PF05667.11 KKK17300.1 - 0.075 11.9 30.4 5.9 5.6 21.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF812) APG6_N PF17675.1 KKK17300.1 - 0.1 13.1 40.5 0.16 12.5 17.4 3.0 1 1 2 3 3 3 0 Apg6 coiled-coil region ADIP PF11559.8 KKK17300.1 - 0.1 12.7 34.4 0.081 13.0 14.2 2.9 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding EzrA PF06160.12 KKK17300.1 - 0.16 10.1 28.5 0.22 9.7 10.2 2.1 1 1 0 2 2 2 0 Septation ring formation regulator, EzrA Tex_N PF09371.10 KKK17300.1 - 0.23 11.1 17.3 0.065 12.9 5.3 2.4 2 0 0 2 2 2 0 Tex-like protein N-terminal domain FAM76 PF16046.5 KKK17300.1 - 0.29 10.5 26.3 0.64 9.3 11.8 2.4 1 1 1 2 2 2 0 FAM76 protein DUF4988 PF16378.5 KKK17300.1 - 0.7 9.5 4.8 0.38 10.4 0.3 2.3 2 1 0 2 2 2 0 Domain of unknown function DUF4407 PF14362.6 KKK17300.1 - 0.74 9.1 21.8 3.7 6.8 19.9 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Bacillus_HBL PF05791.11 KKK17300.1 - 1.1 9.1 11.8 0.91 9.3 1.0 3.2 2 1 2 4 4 4 0 Bacillus haemolytic enterotoxin (HBL) FH2 PF02181.23 KKK17300.1 - 1.6 7.8 21.6 1.4 7.9 6.1 2.5 1 1 1 2 2 2 0 Formin Homology 2 Domain BLOC1_2 PF10046.9 KKK17300.1 - 1.6 9.1 18.0 0.67 10.3 1.5 3.7 1 1 3 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Atg14 PF10186.9 KKK17300.1 - 1.9 7.5 29.6 1.1 8.3 13.2 2.1 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF3584 PF12128.8 KKK17300.1 - 2 5.9 33.2 1.4 6.3 14.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) ALMT PF11744.8 KKK17300.1 - 2.6 6.8 12.8 3.2 6.5 12.8 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter Cep57_MT_bd PF06657.13 KKK17300.1 - 3.3 8.2 27.4 0.089 13.3 4.2 5.0 2 1 1 5 5 5 0 Centrosome microtubule-binding domain of Cep57 TMF_TATA_bd PF12325.8 KKK17300.1 - 3.9 7.7 30.8 0.59 10.4 8.6 4.4 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding TMPIT PF07851.13 KKK17300.1 - 4.7 6.4 27.2 2.3 7.4 7.7 2.7 1 1 2 3 3 3 0 TMPIT-like protein Fib_alpha PF08702.10 KKK17300.1 - 7.2 6.8 22.7 1.9 8.7 5.6 3.3 1 1 2 4 4 4 0 Fibrinogen alpha/beta chain family Csm1_N PF18504.1 KKK17300.1 - 7.8 6.9 24.0 0.54 10.6 6.4 4.7 2 2 3 5 5 5 0 Csm1 N-terminal domain Exonuc_VII_L PF02601.15 KKK17300.1 - 8.5 5.8 28.8 16 5.0 17.3 2.1 1 1 1 2 2 2 0 Exonuclease VII, large subunit DUF5344 PF17279.2 KKK17300.1 - 8.8 7.0 12.4 1.7 9.3 2.2 3.4 1 1 1 3 3 3 0 Family of unknown function (DUF5344) GPI-anchored PF10342.9 KKK17301.1 - 1.2e-13 51.6 1.3 2.5e-13 50.6 1.3 1.5 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family TFIIF_beta PF02270.15 KKK17302.1 - 2e-29 101.5 0.8 3.7e-29 100.7 0.8 1.4 1 0 0 1 1 1 1 TFIIF, beta subunit HTH domain TFIIF_beta_N PF17683.1 KKK17302.1 - 2.7e-28 99.3 0.4 5.7e-28 98.3 0.4 1.6 1 0 0 1 1 1 1 TFIIF, beta subunit N-terminus Tau95 PF09734.9 KKK17302.1 - 0.015 16.1 2.3 0.035 14.9 2.3 1.7 1 1 0 1 1 1 0 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain Fungal_trans PF04082.18 KKK17304.1 - 9.7e-18 64.1 0.0 1.6e-17 63.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK17304.1 - 2.7e-05 24.2 17.5 6.1e-05 23.1 17.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DHquinase_I PF01487.15 KKK17305.1 - 3.1e-43 148.7 0.0 4.5e-43 148.1 0.0 1.2 1 0 0 1 1 1 1 Type I 3-dehydroquinase DENN PF02141.21 KKK17306.1 - 5.4e-57 192.7 0.1 9.3e-57 192.0 0.1 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 KKK17306.1 - 1.1e-14 55.0 0.0 2.3e-14 53.8 0.0 1.6 1 0 0 1 1 1 1 uDENN domain dDENN PF03455.19 KKK17306.1 - 1.3e-12 47.5 0.9 6.3e-12 45.3 0.4 2.5 2 0 0 2 2 2 1 dDENN domain C1_2 PF03107.16 KKK17306.1 - 1e-06 29.0 4.5 1.9e-06 28.1 4.5 1.5 1 0 0 1 1 1 1 C1 domain C1_1 PF00130.22 KKK17306.1 - 0.0022 17.8 10.4 0.0043 16.9 10.4 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Zf_RING PF16744.5 KKK17306.1 - 0.027 14.6 5.2 0.058 13.5 5.2 1.5 1 0 0 1 1 1 0 KIAA1045 RING finger PHD PF00628.29 KKK17306.1 - 0.2 11.6 9.6 0.052 13.4 6.0 1.9 1 1 1 2 2 2 0 PHD-finger Zn_ribbon_17 PF17120.5 KKK17306.1 - 0.37 10.5 6.7 0.81 9.4 6.7 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Mt_ATP-synt_D PF05873.12 KKK17307.1 - 9e-23 80.8 2.7 1.1e-22 80.6 2.7 1.0 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) Herpes_TK_C PF08465.10 KKK17307.1 - 0.058 13.1 0.2 0.15 11.8 0.1 1.7 1 1 0 1 1 1 0 Thymidine kinase from Herpesvirus C-terminal HR1 PF02185.16 KKK17307.1 - 0.16 12.1 4.8 6.6 6.9 0.9 2.3 2 0 0 2 2 2 0 Hr1 repeat DUF2408 PF10303.9 KKK17307.1 - 0.17 12.4 1.7 0.29 11.7 1.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) Enkurin PF13864.6 KKK17307.1 - 0.23 11.9 3.9 2.2 8.8 3.9 2.2 1 1 0 1 1 1 0 Calmodulin-binding NAC PF01849.18 KKK17308.1 - 2.7e-23 81.7 0.0 3e-22 78.3 0.0 2.2 2 0 0 2 2 2 1 NAC domain Cytomega_UL84 PF06284.11 KKK17308.1 - 0.33 9.4 1.3 0.38 9.2 1.3 1.1 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein SelP_N PF04592.14 KKK17308.1 - 0.63 9.4 5.0 1 8.7 5.0 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region COPI_C PF06957.11 KKK17308.1 - 2.4 6.8 8.0 3.4 6.3 8.0 1.1 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus Myc_N PF01056.18 KKK17308.1 - 3.6 7.4 8.0 1.9 8.3 5.7 1.5 1 1 1 2 2 2 0 Myc amino-terminal region Ribosomal_L14e PF01929.17 KKK17309.1 - 2.8e-29 101.4 0.2 4.7e-29 100.7 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.29 KKK17309.1 - 1.1e-07 31.6 1.3 2e-07 30.7 1.3 1.5 1 0 0 1 1 1 1 KOW motif Prot_ATP_ID_OB PF16450.5 KKK17309.1 - 0.097 12.6 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Proteasomal ATPase OB C-terminal domain YIF1 PF03878.15 KKK17310.1 - 4.1e-101 337.5 3.4 4.8e-101 337.3 3.4 1.0 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.17 KKK17310.1 - 8.9e-06 25.5 6.2 8.9e-06 25.5 6.2 1.8 2 0 0 2 2 2 1 Yip1 domain SRP-alpha_N PF04086.13 KKK17311.1 - 1.1e-78 265.2 0.0 1.4e-78 264.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54 PF00448.22 KKK17311.1 - 3.3e-50 170.4 0.0 5.5e-50 169.7 0.0 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.19 KKK17311.1 - 1.3e-10 41.4 0.1 3.5e-10 39.9 0.1 1.8 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain MeaB PF03308.16 KKK17311.1 - 9.2e-06 24.8 0.0 1.7e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 KKK17311.1 - 7.1e-05 22.6 0.0 0.00014 21.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KKK17311.1 - 0.0032 17.8 0.0 0.0072 16.7 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_31 PF13614.6 KKK17311.1 - 0.038 13.9 0.1 0.24 11.3 0.0 2.0 1 1 1 2 2 2 0 AAA domain CbiA PF01656.23 KKK17311.1 - 0.045 13.8 0.0 0.17 12.0 0.0 2.0 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Fer4_NifH PF00142.18 KKK17311.1 - 0.054 12.9 0.0 0.096 12.1 0.0 1.4 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_24 PF13479.6 KKK17311.1 - 0.13 12.0 0.0 0.42 10.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KKK17311.1 - 0.15 12.6 0.0 0.68 10.4 0.0 2.1 2 0 0 2 2 2 0 ABC transporter MFS_1 PF07690.16 KKK17312.1 - 2.2e-40 138.7 44.6 1e-34 120.0 16.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KKK17312.1 - 2.6e-10 39.8 12.0 1.3e-09 37.5 0.2 2.4 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.7 KKK17312.1 - 3.1e-06 26.3 5.7 8.1e-06 24.9 0.1 3.0 2 1 0 2 2 2 1 MFS_1 like family MFS_4 PF06779.14 KKK17312.1 - 0.00024 20.5 0.9 0.00024 20.5 0.9 2.5 3 0 0 3 3 3 1 Uncharacterised MFS-type transporter YbfB MFS_2 PF13347.6 KKK17312.1 - 0.0015 17.2 14.1 0.004 15.8 1.7 3.3 2 1 1 3 3 3 2 MFS/sugar transport protein TRI12 PF06609.13 KKK17312.1 - 0.0036 15.8 1.0 0.0058 15.1 1.0 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF2530 PF10745.9 KKK17312.1 - 0.065 13.5 2.0 1.7 9.0 1.1 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) TPR_12 PF13424.6 KKK17313.1 - 1.2e-22 79.9 7.4 3.6e-10 40.0 3.7 4.8 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_10 PF13374.6 KKK17313.1 - 2.2e-18 65.5 5.8 2.9e-06 27.0 0.4 6.1 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_7 PF13176.6 KKK17313.1 - 3.6e-06 26.6 8.2 0.081 13.0 0.1 5.0 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 KKK17313.1 - 0.00097 19.2 11.0 0.45 10.9 0.6 6.2 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_2 PF07719.17 KKK17313.1 - 0.0016 18.4 15.0 3.5 8.0 1.1 7.0 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_16 PF13432.6 KKK17313.1 - 0.0079 16.8 0.1 0.0079 16.8 0.1 4.8 4 2 1 5 5 4 1 Tetratricopeptide repeat zf-C2H2 PF00096.26 KKK17313.1 - 0.012 16.1 0.1 0.012 16.1 0.1 4.1 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KKK17313.1 - 0.015 16.1 0.1 0.015 16.1 0.1 4.4 5 0 0 5 5 3 0 C2H2-type zinc finger zf-met PF12874.7 KKK17313.1 - 0.042 14.2 2.8 0.14 12.6 0.1 3.0 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KKK17313.1 - 0.043 14.1 0.1 0.043 14.1 0.1 3.4 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding RXT2_N PF08595.11 KKK17313.1 - 0.052 13.6 0.2 0.052 13.6 0.2 2.6 2 0 0 2 2 2 0 RXT2-like, N-terminal zf_UBZ PF18439.1 KKK17313.1 - 0.36 10.5 2.0 7.2 6.3 0.1 2.9 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger TPR_1 PF00515.28 KKK17313.1 - 0.69 9.8 3.4 24 5.0 0.5 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 KKK17313.1 - 1.1 10.3 13.7 28 5.9 0.2 6.1 4 2 2 6 6 6 0 Tetratricopeptide repeat MRI PF15325.6 KKK17313.1 - 2.9 9.0 6.8 14 6.8 6.8 2.2 1 0 0 1 1 1 0 Modulator of retrovirus infection Sporozoite_P67 PF05642.11 KKK17313.1 - 3.4 5.7 13.9 6.9 4.6 13.9 1.4 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Inp1 PF12634.7 KKK17313.1 - 4.2 7.4 7.0 39 4.2 0.1 2.6 2 0 0 2 2 2 0 Inheritance of peroxisomes protein 1 zinc_ribbon_9 PF14369.6 KKK17313.1 - 4.2 7.7 8.8 5.3 7.4 2.5 3.5 3 0 0 3 3 3 0 zinc-ribbon HypA PF01155.19 KKK17313.1 - 8.1 6.5 9.2 0.92 9.5 0.9 3.0 2 1 1 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA YpzG PF14139.6 KKK17316.1 - 0.07 13.3 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 YpzG-like protein DUF1682 PF07946.14 KKK17316.1 - 9 5.4 8.1 13 4.9 8.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) MatK_N PF01824.18 KKK17317.1 - 0.13 11.9 0.1 0.13 11.9 0.1 1.2 1 0 0 1 1 1 0 MatK/TrnK amino terminal region PGM_PMM_I PF02878.16 KKK17318.1 - 1.2e-31 109.2 0.1 1.9e-31 108.6 0.1 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 KKK17318.1 - 6.1e-26 90.9 0.0 1.2e-25 89.9 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 KKK17318.1 - 7.5e-15 55.4 0.0 1.5e-14 54.5 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 KKK17318.1 - 3.7e-07 30.2 0.0 8.7e-07 29.0 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain ATP-grasp_2 PF08442.10 KKK17319.1 - 1.5e-54 184.6 0.0 2.1e-54 184.2 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.19 KKK17319.1 - 1.9e-10 40.8 0.2 3e-10 40.1 0.2 1.3 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 KKK17319.1 - 3.1e-10 39.9 0.0 1.4e-09 37.7 0.0 1.9 1 1 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 KKK17319.1 - 0.0085 15.9 0.0 0.023 14.5 0.0 1.8 1 1 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp PF02222.22 KKK17319.1 - 0.019 14.6 0.0 0.057 13.0 0.0 1.7 1 1 0 1 1 1 0 ATP-grasp domain CPSase_L_D2 PF02786.17 KKK17319.1 - 0.045 13.2 0.0 0.1 12.1 0.0 1.6 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain VEGFR-2_TMD PF17988.1 KKK17320.1 - 0.21 11.1 1.2 0.38 10.2 1.2 1.3 1 0 0 1 1 1 0 VEGFR-2 Transmembrane domain TauD PF02668.16 KKK17321.1 - 5e-05 23.2 0.0 7.6e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 KKK17321.1 - 0.066 12.3 0.0 0.097 11.8 0.0 1.2 1 0 0 1 1 1 0 CsiD AMP-binding PF00501.28 KKK17322.1 - 1.2e-64 218.4 0.0 1.9e-64 217.8 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 KKK17322.1 - 3.8e-18 65.4 0.0 9.8e-09 34.4 0.0 3.4 4 0 0 4 4 4 2 Condensation domain PP-binding PF00550.25 KKK17322.1 - 2.2e-10 40.8 0.0 5e-10 39.6 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KKK17322.1 - 0.0032 18.4 0.0 0.01 16.8 0.0 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain 2OG-FeII_Oxy PF03171.20 KKK17324.1 - 2.9e-13 50.2 0.0 1.4e-12 48.0 0.0 1.9 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 KKK17324.1 - 3.1e-07 31.2 0.0 5.1e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Sulfotransfer_3 PF13469.6 KKK17325.1 - 0.028 14.8 0.2 0.83 10.0 0.0 2.5 3 0 0 3 3 3 0 Sulfotransferase family Aldo_ket_red PF00248.21 KKK17326.1 - 4.9e-28 98.2 0.0 9.3e-09 34.9 0.0 3.0 1 1 2 3 3 3 3 Aldo/keto reductase family AMP-binding PF00501.28 KKK17327.1 - 5.9e-68 229.4 0.0 1e-67 228.6 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 KKK17327.1 - 6.3e-37 127.1 0.0 2e-36 125.5 0.0 1.9 1 1 0 1 1 1 1 Male sterility protein Condensation PF00668.20 KKK17327.1 - 1.3e-33 116.4 0.0 2.6e-33 115.4 0.0 1.5 1 0 0 1 1 1 1 Condensation domain Epimerase PF01370.21 KKK17327.1 - 9.5e-12 44.9 0.0 1.8e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 KKK17327.1 - 3e-06 27.5 0.1 8.5e-05 22.8 0.1 3.1 2 0 0 2 2 2 1 Phosphopantetheine attachment site Semialdhyde_dh PF01118.24 KKK17327.1 - 0.00036 21.0 0.0 0.00092 19.6 0.0 1.7 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 KKK17327.1 - 0.0011 18.0 0.0 0.0022 17.1 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 KKK17327.1 - 0.025 13.7 0.0 0.094 11.8 0.0 2.0 1 1 0 1 1 1 0 RmlD substrate binding domain AMP-binding_C PF13193.6 KKK17327.1 - 0.3 12.1 6.5 0.12 13.4 0.4 3.2 3 0 0 3 3 3 0 AMP-binding enzyme C-terminal domain MFS_1 PF07690.16 KKK17328.1 - 9e-31 107.1 29.2 1.2e-30 106.7 29.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.20 KKK17328.1 - 2e-06 26.4 5.3 6e-06 24.8 4.8 1.8 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family Sugar_tr PF00083.24 KKK17328.1 - 1.4e-05 24.2 8.1 1.4e-05 24.2 8.1 1.9 2 0 0 2 2 2 1 Sugar (and other) transporter EptA_B_N PF08019.12 KKK17328.1 - 0.004 17.1 4.3 0.017 15.0 1.8 2.5 2 0 0 2 2 2 1 Phosphoethanolamine transferase EptA/EptB LacY_symp PF01306.19 KKK17328.1 - 0.02 13.7 0.9 0.02 13.7 0.9 1.8 2 0 0 2 2 2 0 LacY proton/sugar symporter MFS_1_like PF12832.7 KKK17328.1 - 0.32 9.8 10.6 0.79 8.5 10.6 1.7 1 1 0 1 1 1 0 MFS_1 like family RNase_T PF00929.24 KKK17329.1 - 5e-19 69.4 0.0 6e-19 69.2 0.0 1.0 1 0 0 1 1 1 1 Exonuclease GFO_IDH_MocA PF01408.22 KKK17330.1 - 5.2e-09 37.0 0.0 2e-08 35.1 0.0 2.0 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Ilar_coat PF01787.16 KKK17330.1 - 0.11 12.3 0.1 0.2 11.4 0.1 1.4 1 0 0 1 1 1 0 Ilarvirus coat protein peroxidase PF00141.23 KKK17331.1 - 4.4e-43 147.6 0.0 6.7e-43 147.0 0.0 1.3 1 0 0 1 1 1 1 Peroxidase ArfGap PF01412.18 KKK17332.1 - 1.3e-36 125.3 0.3 2e-36 124.6 0.3 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf UBA PF00627.31 KKK17332.1 - 0.049 13.6 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 UBA/TS-N domain Sec7 PF01369.20 KKK17342.1 - 1.1e-60 204.4 0.0 1.9e-60 203.7 0.0 1.4 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 KKK17342.1 - 4.4e-18 65.7 0.0 1.3e-16 60.9 0.0 2.7 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF3337 PF11816.8 KKK17343.1 - 1.1e-54 184.9 0.0 2.7e-54 183.6 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3337) ATP_bind_3 PF01171.20 KKK17343.1 - 1.9e-42 145.1 0.0 4.3e-42 143.9 0.0 1.6 1 1 0 1 1 1 1 PP-loop family WD40 PF00400.32 KKK17343.1 - 4.4e-14 52.6 15.1 6.2e-05 23.7 0.1 6.2 5 0 0 5 5 5 3 WD domain, G-beta repeat Nup160 PF11715.8 KKK17343.1 - 0.0052 15.5 0.4 0.081 11.5 0.1 2.7 3 0 0 3 3 3 1 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 KKK17343.1 - 0.0057 16.9 0.2 0.11 12.8 0.1 2.8 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain RhoGEF PF00621.20 KKK17344.1 - 1.2e-22 81.0 0.0 2.8e-22 79.9 0.0 1.7 1 0 0 1 1 1 1 RhoGEF domain DUF3507 PF12015.8 KKK17344.1 - 3.9e-08 33.2 0.0 6.4e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3507) FAM184 PF15665.5 KKK17344.1 - 0.015 15.1 2.2 0.036 13.8 2.2 1.6 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B Cep57_CLD_2 PF14197.6 KKK17344.1 - 0.08 13.0 1.3 0.37 10.9 1.3 2.1 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 RhoGAP PF00620.27 KKK17344.1 - 0.085 12.7 0.2 12 5.7 0.0 2.8 2 0 0 2 2 2 0 RhoGAP domain ZapB PF06005.12 KKK17344.1 - 0.46 11.0 3.2 0.44 11.0 0.4 2.4 2 0 0 2 2 2 0 Cell division protein ZapB Pkinase PF00069.25 KKK17345.1 - 3.7e-44 151.1 0.0 2.1e-42 145.3 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KKK17345.1 - 1.5e-19 70.3 0.0 2.4e-19 69.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KKK17345.1 - 0.016 15.1 0.1 0.048 13.6 0.1 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KKK17345.1 - 0.031 13.2 0.0 0.057 12.3 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Mito_carr PF00153.27 KKK17346.1 - 1.3e-40 137.3 3.3 4.5e-16 58.5 0.1 4.2 3 2 0 3 3 3 3 Mitochondrial carrier protein Svf1 PF08622.10 KKK17347.1 - 8e-07 29.2 0.8 1e-06 28.9 0.8 1.1 1 0 0 1 1 1 1 Svf1-like N-terminal lipocalin domain LisH_2 PF16045.5 KKK17347.1 - 0.083 11.9 0.2 0.14 11.2 0.2 1.4 1 0 0 1 1 1 0 LisH Ribosomal_L11 PF00298.19 KKK17348.1 - 1.7e-21 76.5 0.4 2.8e-21 75.8 0.1 1.5 2 0 0 2 2 2 1 Ribosomal protein L11, RNA binding domain Ribosomal_L11_N PF03946.14 KKK17348.1 - 1.3e-13 50.5 0.5 2.3e-13 49.7 0.5 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain RNase_PH PF01138.21 KKK17349.1 - 4.5e-30 104.8 1.4 6.4e-30 104.3 0.6 1.6 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 Pro_isomerase PF00160.21 KKK17350.1 - 5.5e-14 52.7 0.2 6e-14 52.6 0.2 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Ssu72 PF04722.13 KKK17351.1 - 2.4e-82 275.1 0.0 2.8e-82 274.9 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein PRIMA1 PF16101.5 KKK17351.1 - 0.59 10.2 3.6 0.99 9.5 3.6 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 CAP_N PF01213.19 KKK17351.1 - 3.4 7.1 8.3 5.5 6.4 8.3 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal SNF2_N PF00176.23 KKK17352.1 - 1.3e-51 175.4 0.1 2e-51 174.8 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain VIGSSK PF14773.6 KKK17352.1 - 4.1e-26 90.9 0.7 1.1e-25 89.5 0.7 1.8 1 0 0 1 1 1 1 Helicase-associated putative binding domain, C-terminal Helicase_C PF00271.31 KKK17352.1 - 4.9e-22 78.4 0.0 3e-19 69.4 0.0 3.7 4 0 0 4 4 4 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 KKK17352.1 - 2.8e-07 30.0 0.0 6.6e-07 28.8 0.0 1.6 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 KKK17352.1 - 1.9e-06 28.0 0.3 1.2e-05 25.4 0.0 2.5 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit DUF3605 PF12239.8 KKK17353.1 - 7.1e-55 185.5 0.1 8.7e-55 185.3 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) Isochorismatase PF00857.20 KKK17354.1 - 3.5e-22 79.4 0.1 6.9e-22 78.5 0.1 1.5 1 1 0 1 1 1 1 Isochorismatase family Oxysterol_BP PF01237.18 KKK17355.1 - 7.9e-91 304.7 0.1 2.9e-88 296.2 0.1 2.1 1 1 0 1 1 1 1 Oxysterol-binding protein GTP_EFTU PF00009.27 KKK17359.1 - 9.4e-65 217.8 0.1 1.6e-64 217.0 0.1 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 KKK17359.1 - 1.2e-32 112.3 0.0 2.6e-32 111.1 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 KKK17359.1 - 4e-21 74.8 0.0 1.3e-20 73.3 0.0 1.9 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KKK17359.1 - 2.9e-13 50.0 0.0 8.3e-13 48.5 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 KKK17359.1 - 4.5e-11 42.7 0.0 1.7e-10 40.8 0.0 2.0 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 KKK17359.1 - 4e-05 23.7 0.0 0.00013 22.0 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase Solute_trans_a PF03619.16 KKK17361.1 - 1.3e-91 306.9 3.1 1.6e-91 306.5 3.1 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha PWI PF01480.17 KKK17362.1 - 1.3e-13 51.0 0.1 2.8e-13 50.0 0.1 1.6 1 0 0 1 1 1 1 PWI domain Nup35_RRM_2 PF14605.6 KKK17362.1 - 2e-07 30.9 0.0 0.00011 22.1 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_1 PF00076.22 KKK17362.1 - 8.3e-07 28.7 0.1 6.1e-05 22.8 0.0 2.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KKK17362.1 - 0.00011 22.0 0.0 0.00034 20.4 0.0 1.8 1 0 0 1 1 1 1 Occluded RNA-recognition motif zf-CCCH PF00642.24 KKK17362.1 - 0.00064 19.6 0.9 0.0012 18.7 0.9 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF1330 PF07045.11 KKK17362.1 - 0.049 14.0 0.1 3.4 8.1 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1330) HEAT_2 PF13646.6 KKK17362.1 - 0.078 13.4 0.2 0.17 12.3 0.2 1.5 1 0 0 1 1 1 0 HEAT repeats zf_CCCH_4 PF18345.1 KKK17362.1 - 0.088 12.9 0.6 0.16 12.0 0.6 1.5 1 0 0 1 1 1 0 Zinc finger domain RRM_3 PF08777.11 KKK17362.1 - 0.095 12.7 7.0 0.6 10.2 0.0 3.4 3 0 0 3 3 3 0 RNA binding motif Borrelia_P83 PF05262.11 KKK17362.1 - 0.17 10.3 8.3 0.25 9.8 8.3 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein PHM7_cyt PF14703.6 KKK17362.1 - 0.29 11.4 4.3 1.2 9.4 0.0 2.8 2 0 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter Torus PF16131.5 KKK17362.1 - 0.4 11.4 0.1 0.4 11.4 0.1 2.2 2 0 0 2 2 2 0 Torus domain DUF4407 PF14362.6 KKK17362.1 - 2.3 7.5 9.5 3.8 6.8 9.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Ubie_methyltran PF01209.18 KKK17363.1 - 4.9e-80 268.2 0.0 6.5e-80 267.8 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 KKK17363.1 - 3.6e-16 59.7 0.0 6.3e-16 58.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KKK17363.1 - 9.1e-15 55.1 0.0 1.9e-14 54.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KKK17363.1 - 2e-11 43.9 0.0 2.5e-11 43.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KKK17363.1 - 3.5e-09 37.3 0.0 6e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KKK17363.1 - 1.2e-06 28.5 0.0 1.6e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 KKK17363.1 - 0.09 12.6 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Hypothetical methyltransferase Ig_mannosidase PF17753.1 KKK17364.1 - 3e-20 71.7 0.1 7.8e-20 70.4 0.1 1.8 1 0 0 1 1 1 1 Ig-fold domain Mannosidase_ig PF17786.1 KKK17364.1 - 2e-12 47.6 0.0 5e-12 46.3 0.0 1.8 1 0 0 1 1 1 1 Mannosidase Ig/CBM-like domain DUF4299 PF14132.6 KKK17364.1 - 0.021 14.3 0.0 0.037 13.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4299) E1_dh PF00676.20 KKK17365.1 - 3.6e-87 292.1 0.0 4.4e-87 291.8 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 KKK17365.1 - 0.00015 21.6 0.0 0.0021 17.9 0.0 2.2 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain XFP_N PF09364.10 KKK17365.1 - 0.0073 15.2 0.0 0.015 14.1 0.0 1.5 1 0 0 1 1 1 1 XFP N-terminal domain SidC_N PF18219.1 KKK17365.1 - 0.17 10.9 0.1 0.24 10.3 0.1 1.1 1 0 0 1 1 1 0 SidC N-terminal domain Elongin_A PF06881.11 KKK17365.1 - 0.65 10.5 4.1 1.5 9.4 4.1 1.5 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A Thi4 PF01946.17 KKK17381.1 - 8.3e-111 368.9 0.0 1e-110 368.6 0.0 1.1 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 KKK17381.1 - 1.2e-07 31.7 0.3 2.1e-07 30.8 0.3 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KKK17381.1 - 3.6e-06 27.1 0.2 2.1e-05 24.7 0.2 2.4 2 1 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KKK17381.1 - 7.3e-05 22.0 0.4 0.00013 21.1 0.4 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_9 PF13454.6 KKK17381.1 - 0.00081 19.4 0.9 0.002 18.2 0.1 2.0 2 1 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 KKK17381.1 - 0.0013 18.0 0.0 0.0022 17.3 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KKK17381.1 - 0.0094 15.1 0.5 0.033 13.3 0.5 1.9 2 0 0 2 2 2 1 FAD binding domain FAD_binding_3 PF01494.19 KKK17381.1 - 0.041 13.1 0.0 0.059 12.6 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.6 KKK17381.1 - 0.053 12.8 0.0 0.088 12.0 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KKK17381.1 - 0.11 11.9 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Trp_halogenase PF04820.14 KKK17381.1 - 0.12 11.2 0.2 0.17 10.7 0.2 1.1 1 0 0 1 1 1 0 Tryptophan halogenase HI0933_like PF03486.14 KKK17381.1 - 0.21 10.2 0.4 0.32 9.6 0.4 1.2 1 0 0 1 1 1 0 HI0933-like protein Mqo PF06039.15 KKK17381.1 - 0.23 10.0 0.0 0.73 8.3 0.0 1.7 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) WD40 PF00400.32 KKK17382.1 - 3.9e-55 182.6 20.4 8.1e-12 45.5 0.2 7.7 8 0 0 8 8 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKK17382.1 - 9.7e-23 80.3 0.0 3.8e-05 23.9 0.0 6.2 3 1 4 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KKK17382.1 - 4.2e-09 35.8 0.7 0.33 9.9 0.0 4.9 1 1 4 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KKK17382.1 - 5e-09 36.3 0.0 0.0042 17.0 0.0 2.6 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KKK17382.1 - 4e-07 29.1 2.7 0.38 9.3 1.0 4.8 2 2 2 4 4 4 3 Nucleoporin Nup120/160 WD40_like PF17005.5 KKK17382.1 - 1e-05 25.0 0.0 0.028 13.8 0.0 3.4 3 1 1 4 4 4 2 WD40-like domain PD40 PF07676.12 KKK17382.1 - 0.0001 22.1 0.0 4.3 7.4 0.0 4.5 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat VID27 PF08553.10 KKK17382.1 - 0.011 14.8 0.2 2.1 7.3 0.0 3.3 2 1 2 4 4 4 0 VID27 C-terminal WD40-like domain Frtz PF11768.8 KKK17382.1 - 0.032 12.6 0.0 0.074 11.4 0.0 1.5 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz CHAP PF05257.16 KKK17382.1 - 0.052 14.1 4.6 0.15 12.7 0.3 3.2 3 0 0 3 3 3 0 CHAP domain PALB2_WD40 PF16756.5 KKK17382.1 - 0.14 11.0 0.9 0.72 8.7 0.1 2.4 1 1 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain IKI3 PF04762.12 KKK17382.1 - 0.31 9.0 0.0 0.5 8.3 0.0 1.3 1 0 0 1 1 1 0 IKI3 family SWI-SNF_Ssr4 PF08549.10 KKK17383.1 - 3e-238 793.1 16.8 1.4e-237 790.9 16.8 1.9 1 1 0 1 1 1 1 Fungal domain of unknown function (DUF1750) Laminin_I PF06008.14 KKK17383.1 - 0.22 11.2 3.9 0.36 10.5 3.9 1.2 1 0 0 1 1 1 0 Laminin Domain I MFS_1 PF07690.16 KKK17384.1 - 3.4e-34 118.3 25.9 3.4e-34 118.3 25.9 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.7 KKK17384.1 - 1 8.1 12.1 0.02 13.8 3.9 2.1 3 0 0 3 3 3 0 MFS_1 like family Exo_endo_phos PF03372.23 KKK17385.1 - 4.1e-18 65.8 0.0 9.1e-18 64.6 0.0 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Luciferase_cat PF10285.9 KKK17385.1 - 0.16 11.3 0.2 0.32 10.3 0.0 1.5 2 0 0 2 2 2 0 Luciferase catalytic domain S_4TM PF18159.1 KKK17385.1 - 0.21 10.8 0.1 0.38 10.0 0.1 1.3 1 0 0 1 1 1 0 SMODS-associating 4TM effector domain Pkinase PF00069.25 KKK17386.1 - 1.7e-16 60.4 0.0 3.7e-08 33.1 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KKK17386.1 - 0.041 13.2 3.0 1 8.6 0.0 2.5 2 1 1 3 3 3 0 Protein tyrosine kinase Arf PF00025.21 KKK17387.1 - 5.2e-43 146.5 0.0 6.2e-43 146.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 KKK17387.1 - 2.3e-18 66.3 0.0 2.6e-18 66.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KKK17387.1 - 5.9e-15 55.6 0.0 9.3e-15 54.9 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 KKK17387.1 - 3.5e-08 33.5 0.0 5.3e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KKK17387.1 - 1.6e-06 27.7 0.0 1.9e-06 27.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 KKK17387.1 - 3.8e-06 26.5 0.0 4.5e-06 26.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 KKK17387.1 - 0.00022 20.5 0.1 0.001 18.4 0.0 2.1 1 1 1 2 2 2 1 G-protein alpha subunit MMR_HSR1_Xtn PF16897.5 KKK17387.1 - 0.0083 16.1 0.0 0.014 15.4 0.0 1.3 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain Dynamin_N PF00350.23 KKK17387.1 - 0.0085 16.2 0.1 0.054 13.5 0.1 2.0 1 1 1 2 2 2 1 Dynamin family FeoB_N PF02421.18 KKK17387.1 - 0.014 14.9 0.2 0.091 12.3 0.0 2.1 2 1 0 2 2 2 0 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KKK17387.1 - 0.051 13.5 0.0 11 5.9 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase DUF1979 PF09322.10 KKK17387.1 - 0.25 11.3 0.9 9.8 6.2 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1979) RCR PF12273.8 KKK17388.1 - 1.2e-22 80.8 11.4 1.6e-22 80.4 11.4 1.2 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red LysE PF01810.18 KKK17388.1 - 0.003 17.0 0.3 0.004 16.6 0.3 1.1 1 0 0 1 1 1 1 LysE type translocator SARAF PF06682.12 KKK17388.1 - 0.0046 16.7 0.9 0.0057 16.4 0.9 1.3 1 1 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis CYYR1 PF10873.8 KKK17388.1 - 0.0093 16.4 2.6 0.0093 16.4 2.6 1.8 1 1 1 2 2 2 1 Cysteine and tyrosine-rich protein 1 Acyl_transf_3 PF01757.22 KKK17388.1 - 0.06 12.4 1.0 0.077 12.0 1.0 1.1 1 0 0 1 1 1 0 Acyltransferase family DUF2207 PF09972.9 KKK17388.1 - 0.11 11.3 0.1 0.13 11.0 0.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF1180 PF06679.12 KKK17388.1 - 1.2 9.5 0.0 1.2 9.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) DUF4381 PF14316.6 KKK17388.1 - 5.3 7.3 7.4 14 5.9 5.6 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4381) Pil1 PF13805.6 KKK17389.1 - 1e-91 307.1 5.5 1e-91 307.1 5.5 1.5 2 0 0 2 2 2 1 Eisosome component PIL1 Proteasome PF00227.26 KKK17390.1 - 3.1e-43 147.5 0.3 1.8e-33 115.6 0.1 2.0 2 0 0 2 2 2 2 Proteasome subunit RNA_pol_Rpb2_6 PF00562.28 KKK17391.1 - 1.2e-117 393.3 0.0 1.6e-117 392.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 KKK17391.1 - 4.3e-35 121.1 0.0 1.3e-34 119.5 0.0 1.7 1 1 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.16 KKK17391.1 - 1e-27 96.1 0.0 3.1e-27 94.5 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_2 PF04561.14 KKK17391.1 - 3.1e-26 92.2 0.0 5.2e-26 91.4 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpa2_4 PF06883.12 KKK17391.1 - 9.9e-26 89.5 0.0 2.2e-25 88.4 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_7 PF04560.20 KKK17391.1 - 1.4e-15 57.4 0.0 1.4e-14 54.3 0.0 2.3 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 7 Ppx-GppA PF02541.16 KKK17392.1 - 3.5e-43 148.1 0.0 5.1e-43 147.5 0.0 1.2 1 0 0 1 1 1 1 Ppx/GppA phosphatase family GDA1_CD39 PF01150.17 KKK17392.1 - 0.0067 15.1 0.1 0.015 14.0 0.0 1.5 2 0 0 2 2 2 1 GDA1/CD39 (nucleoside phosphatase) family Selenoprotein_S PF06936.11 KKK17393.1 - 2.8 7.7 8.8 0.041 13.7 0.8 2.0 2 1 0 2 2 2 0 Selenoprotein S (SelS) Pkinase PF00069.25 KKK17394.1 - 3.9e-74 249.4 0.0 5.3e-74 248.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK17394.1 - 3.2e-30 105.3 0.0 9.6e-22 77.5 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KKK17394.1 - 8.5e-07 28.6 0.1 0.46 9.8 0.0 3.2 3 0 0 3 3 3 3 Kinase-like Pkinase_fungal PF17667.1 KKK17394.1 - 0.024 13.5 0.0 0.047 12.5 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 KKK17394.1 - 0.029 13.7 0.0 0.053 12.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KKK17394.1 - 0.085 12.8 0.0 3.3 7.5 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family His_Phos_2 PF00328.22 KKK17396.1 - 7.1e-12 45.4 0.0 1.9e-10 40.6 0.0 2.1 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Amnionless PF14828.6 KKK17396.1 - 0.13 11.1 0.0 0.18 10.6 0.0 1.1 1 0 0 1 1 1 0 Amnionless ILVD_EDD PF00920.21 KKK17397.1 - 3e-164 547.5 0.3 3.4e-164 547.3 0.3 1.0 1 0 0 1 1 1 1 Dehydratase family eIF-5a PF01287.20 KKK17399.1 - 7.6e-29 99.6 1.4 1.1e-28 99.2 1.4 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 KKK17399.1 - 0.0088 16.1 0.0 0.015 15.3 0.0 1.4 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain Vps52 PF04129.12 KKK17400.1 - 1e-107 361.0 0.0 1.5e-107 360.5 0.0 1.1 1 0 0 1 1 1 1 Vps52 / Sac2 family DAO PF01266.24 KKK17400.1 - 1.6e-62 212.2 0.6 2.6e-62 211.5 0.6 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KKK17400.1 - 2.8e-05 24.3 0.2 0.00045 20.4 0.1 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KKK17400.1 - 0.00028 20.2 0.0 0.0008 18.7 0.0 1.7 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 KKK17400.1 - 0.0066 15.6 1.2 0.028 13.5 1.2 1.9 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KKK17400.1 - 0.022 14.0 0.1 0.16 11.2 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Sec8_exocyst PF04048.14 KKK17400.1 - 0.031 14.1 0.0 0.08 12.8 0.0 1.6 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain Exo70 PF03081.15 KKK17400.1 - 0.054 12.5 0.9 1.7 7.6 0.0 2.8 3 0 0 3 3 3 0 Exo70 exocyst complex subunit Sec3_C PF09763.9 KKK17400.1 - 0.25 9.7 1.4 0.35 9.2 0.2 1.7 1 1 1 2 2 2 0 Exocyst complex component Sec3 zf-H2C2_2 PF13465.6 KKK17401.1 - 5.5e-07 29.7 8.5 5.5e-07 29.7 8.5 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.26 KKK17401.1 - 1.2e-06 28.6 15.2 0.0059 17.0 2.0 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KKK17401.1 - 1.2e-05 25.7 12.9 0.011 16.5 1.8 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger Fungal_trans PF04082.18 KKK17401.1 - 4.1e-05 22.7 0.0 6.9e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-met PF12874.7 KKK17401.1 - 6.6e-05 23.2 8.3 0.043 14.2 0.9 2.5 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KKK17401.1 - 0.0018 18.5 10.3 0.1 12.9 3.6 2.4 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KKK17401.1 - 0.0019 18.2 8.4 0.012 15.6 1.5 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-RING_2 PF13639.6 KKK17401.1 - 0.005 17.1 0.4 2.9 8.3 0.0 3.5 3 0 0 3 3 3 1 Ring finger domain PHD_4 PF16866.5 KKK17401.1 - 0.13 12.4 1.3 0.28 11.3 1.3 1.5 1 0 0 1 1 1 0 PHD-finger CoA_trans PF01144.23 KKK17402.1 - 1.4e-96 322.1 1.6 2.5e-58 197.1 0.4 2.0 2 0 0 2 2 2 2 Coenzyme A transferase DUF531 PF04407.12 KKK17402.1 - 0.035 14.2 0.0 0.24 11.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF531) PPTA PF01239.22 KKK17403.1 - 0.01 15.5 1.2 0.66 9.8 1.3 2.6 2 0 0 2 2 2 0 Protein prenyltransferase alpha subunit repeat CHD5 PF04420.14 KKK17404.1 - 1.8e-60 203.4 3.5 2.3e-60 203.1 3.5 1.1 1 0 0 1 1 1 1 CHD5-like protein VPS11_C PF12451.8 KKK17404.1 - 7.3 6.9 5.8 39 4.6 1.8 2.2 1 1 1 2 2 2 0 Vacuolar protein sorting protein 11 C terminal Pribosyltran PF00156.27 KKK17405.1 - 3.1e-14 52.8 0.4 4.4e-14 52.3 0.4 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain MTHFR PF02219.17 KKK17406.1 - 9.2e-114 379.6 0.0 1.2e-113 379.2 0.0 1.1 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase MHC_I_3 PF16497.5 KKK17406.1 - 0.16 11.4 0.0 0.46 9.9 0.0 1.7 1 0 0 1 1 1 0 MHC-I family domain DUF2418 PF10332.9 KKK17408.1 - 4.3e-34 116.9 1.1 7.4e-34 116.2 0.1 1.9 3 0 0 3 3 3 1 Protein of unknown function (DUF2418) ATP-synt_F PF01990.17 KKK17409.1 - 5.2e-28 97.2 0.0 6.7e-28 96.9 0.0 1.1 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit DUF257 PF03192.13 KKK17409.1 - 0.031 14.1 0.0 0.04 13.7 0.0 1.1 1 0 0 1 1 1 0 Pyrococcus protein of unknown function, DUF257 PIN_8 PF18476.1 KKK17409.1 - 0.12 12.2 0.0 0.14 12.0 0.0 1.1 1 0 0 1 1 1 0 PIN like domain GMC_oxred_N PF00732.19 KKK17412.1 - 2.2e-34 119.2 0.0 2.5e-34 119.0 0.0 1.0 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KKK17412.1 - 2.6e-05 23.5 0.5 3.7e-05 23.0 0.5 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KKK17412.1 - 3.3e-05 23.3 0.1 4.2e-05 22.9 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KKK17412.1 - 4.6e-05 23.6 1.1 0.0001 22.5 0.5 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KKK17412.1 - 5.6e-05 22.4 0.1 9.2e-05 21.7 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 KKK17412.1 - 5.9e-05 22.8 0.6 8.7e-05 22.2 0.6 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KKK17412.1 - 0.0003 19.6 0.2 0.00042 19.1 0.2 1.2 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.17 KKK17412.1 - 0.00047 19.5 0.1 0.0054 16.0 0.1 2.0 2 0 0 2 2 2 1 Thi4 family FAD_oxidored PF12831.7 KKK17412.1 - 0.016 14.6 0.5 0.031 13.6 0.5 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase Trp_halogenase PF04820.14 KKK17412.1 - 0.017 14.0 0.3 0.025 13.4 0.3 1.2 1 0 0 1 1 1 0 Tryptophan halogenase GIDA PF01134.22 KKK17412.1 - 0.026 13.6 0.2 0.039 13.0 0.2 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 KKK17412.1 - 0.032 13.5 0.3 0.048 12.9 0.3 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 KKK17412.1 - 0.037 14.3 0.1 0.063 13.5 0.1 1.3 1 0 0 1 1 1 0 TrkA-N domain Pyr_redox PF00070.27 KKK17412.1 - 0.064 13.8 0.7 0.11 13.0 0.2 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KKK17412.1 - 0.11 12.4 0.1 0.2 11.6 0.1 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding Asparaginase PF00710.20 KKK17433.1 - 3.9e-59 199.4 0.0 5.6e-59 198.9 0.0 1.2 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 KKK17433.1 - 2e-26 92.5 0.1 3.8e-26 91.5 0.1 1.5 1 0 0 1 1 1 1 Glutaminase/Asparaginase C-terminal domain Ank_2 PF12796.7 KKK17433.1 - 1e-11 45.2 0.1 4.8e-11 43.1 0.1 2.0 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KKK17433.1 - 7.6e-09 35.1 1.7 0.0082 16.6 0.0 4.3 5 0 0 5 5 5 2 Ankyrin repeat Ank_4 PF13637.6 KKK17433.1 - 2.7e-08 34.2 1.6 0.00026 21.5 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KKK17433.1 - 1.5e-07 31.5 1.1 0.0066 16.9 0.1 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 KKK17433.1 - 6.5e-07 29.5 1.5 3.7e-06 27.1 0.3 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) MTTB PF06253.11 KKK17433.1 - 0.063 11.2 0.1 0.099 10.6 0.1 1.2 1 0 0 1 1 1 0 Trimethylamine methyltransferase (MTTB) DUF1996 PF09362.10 KKK17434.1 - 3.7e-80 269.3 0.1 3.7e-80 269.3 0.1 2.3 2 1 0 2 2 2 1 Domain of unknown function (DUF1996) SOG2 PF10428.9 KKK17434.1 - 0.26 10.5 18.1 0.35 10.0 18.1 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein CPSF100_C PF13299.6 KKK17434.1 - 0.59 10.3 3.1 1 9.5 3.1 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal LEA_3 PF03242.13 KKK17434.1 - 3.2 8.5 9.0 0.7 10.7 4.5 2.3 2 0 0 2 2 2 0 Late embryogenesis abundant protein RIFIN PF02009.16 KKK17434.1 - 6.9 6.5 9.2 9.9 5.9 9.2 1.2 1 0 0 1 1 1 0 Rifin Phosphoesterase PF04185.14 KKK17435.1 - 8.9e-43 146.8 0.2 1.5e-42 146.0 0.2 1.4 1 1 0 1 1 1 1 Phosphoesterase family Phosducin PF02114.16 KKK17436.1 - 2.5e-12 46.3 0.0 1e-09 37.8 0.0 2.1 2 0 0 2 2 2 2 Phosducin WD40 PF00400.32 KKK17437.1 - 1.6e-39 133.1 21.4 3.9e-06 27.5 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKK17437.1 - 5.4e-16 58.7 0.0 0.00044 20.5 0.1 5.2 1 1 5 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KKK17437.1 - 2.8e-05 24.1 0.0 0.11 12.3 0.0 2.8 1 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 KKK17437.1 - 0.0008 18.8 0.0 0.022 14.1 0.0 2.8 2 1 1 3 3 3 1 WD40-like domain Ge1_WD40 PF16529.5 KKK17437.1 - 0.046 12.7 0.2 21 3.9 0.0 3.6 3 1 1 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein RTA1 PF04479.13 KKK17478.1 - 3.7e-71 239.0 11.7 3.7e-71 239.0 11.7 1.3 2 0 0 2 2 2 1 RTA1 like protein Ninjurin PF04923.12 KKK17478.1 - 3.2 7.7 6.2 18 5.3 0.5 3.0 3 1 0 3 3 3 0 Ninjurin XFP_N PF09364.10 KKK17479.1 - 2.4e-143 477.4 0.0 1e-141 472.0 0.0 2.1 1 1 0 1 1 1 1 XFP N-terminal domain XFP PF03894.15 KKK17479.1 - 9.2e-76 253.5 0.0 1.4e-75 252.9 0.0 1.3 1 0 0 1 1 1 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase XFP_C PF09363.10 KKK17479.1 - 4.6e-46 156.9 0.2 4.7e-29 101.3 0.0 2.5 1 1 1 2 2 2 2 XFP C-terminal domain TPP_enzyme_C PF02775.21 KKK17479.1 - 0.0049 16.7 0.1 0.011 15.5 0.1 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain SH3_2 PF07653.17 KKK17479.1 - 0.15 11.8 0.1 0.4 10.4 0.1 1.7 1 0 0 1 1 1 0 Variant SH3 domain AAA_16 PF13191.6 KKK17480.1 - 1.5e-07 32.0 0.0 3.2e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain ATPase_2 PF01637.18 KKK17480.1 - 0.0038 17.2 0.0 0.0063 16.5 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_25 PF13481.6 KKK17480.1 - 0.028 14.0 0.0 0.14 11.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KKK17480.1 - 0.075 12.5 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_5 PF07728.14 KKK17480.1 - 0.099 12.6 0.1 0.38 10.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Glycophorin_A PF01102.18 KKK17493.1 - 0.026 14.8 5.4 0.042 14.1 5.4 1.3 1 0 0 1 1 1 0 Glycophorin A Pox_A12 PF04651.13 KKK17493.1 - 0.083 12.9 7.1 0.12 12.4 7.1 1.2 1 0 0 1 1 1 0 Poxvirus A12 protein RIFIN PF02009.16 KKK17493.1 - 0.088 12.7 2.2 0.1 12.5 2.2 1.1 1 0 0 1 1 1 0 Rifin Sporozoite_P67 PF05642.11 KKK17493.1 - 0.45 8.5 11.4 0.5 8.4 11.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen FSA_C PF10479.9 KKK17493.1 - 0.78 7.8 11.4 0.85 7.7 11.4 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus DUF3074 PF11274.8 KKK17494.1 - 4.5e-41 140.9 0.1 5.7e-41 140.5 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3074) Glyco_transf_20 PF00982.21 KKK17495.1 - 2.9e-159 530.8 0.0 3.9e-159 530.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 KKK17495.1 - 4.8e-37 127.3 0.0 7.9e-37 126.6 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase zf-H2C2_2 PF13465.6 KKK17497.1 - 0.00069 19.9 0.4 0.00069 19.9 0.4 2.1 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_6 PF13912.6 KKK17497.1 - 0.0014 18.6 0.0 0.0032 17.4 0.0 1.5 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2 PF00096.26 KKK17497.1 - 0.014 15.8 0.1 0.043 14.3 0.1 1.9 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2HC_2 PF13913.6 KKK17497.1 - 0.015 15.2 4.0 0.024 14.6 0.9 2.3 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2H2_4 PF13894.6 KKK17497.1 - 0.036 14.9 0.4 0.18 12.7 0.1 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger TIP49 PF06068.13 KKK17498.1 - 1.7e-153 511.0 1.8 2.1e-153 510.6 1.8 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 KKK17498.1 - 1.9e-21 76.0 0.4 5.8e-21 74.4 0.4 1.9 1 0 0 1 1 1 1 TIP49 AAA-lid domain AAA PF00004.29 KKK17498.1 - 1e-08 35.7 1.3 1.9e-05 25.1 0.0 2.9 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KKK17498.1 - 1.1e-07 31.7 0.7 7.4e-05 22.5 0.0 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KKK17498.1 - 1.4e-06 28.8 0.2 7.8e-06 26.4 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain DnaB_C PF03796.15 KKK17498.1 - 2.7e-06 26.9 1.0 5.2e-06 26.0 1.0 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain Mg_chelatase PF01078.21 KKK17498.1 - 0.00086 18.7 0.9 0.012 15.0 0.5 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KKK17498.1 - 0.0032 17.5 0.2 0.46 10.5 0.0 3.0 2 1 1 3 3 3 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KKK17498.1 - 0.0063 16.8 0.0 0.66 10.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 KKK17498.1 - 0.01 15.6 0.1 4.9 6.8 0.1 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_19 PF13245.6 KKK17498.1 - 0.032 14.6 2.2 0.57 10.5 1.7 2.8 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 KKK17498.1 - 0.039 13.5 0.1 0.089 12.4 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 KKK17498.1 - 0.046 13.5 0.6 0.14 11.9 0.6 1.9 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KKK17498.1 - 0.055 13.6 0.0 0.16 12.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 KKK17498.1 - 0.083 12.0 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_7 PF12775.7 KKK17498.1 - 0.09 12.3 0.3 0.37 10.3 0.0 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_28 PF13521.6 KKK17498.1 - 0.12 12.7 0.0 0.29 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain Sugar_tr PF00083.24 KKK17499.1 - 4.8e-78 263.0 27.0 1e-64 219.1 11.1 2.8 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KKK17499.1 - 8.5e-25 87.4 32.6 1.6e-10 40.5 5.5 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily OATP PF03137.20 KKK17499.1 - 3.1e-06 25.8 4.9 0.00013 20.5 1.2 2.8 2 1 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family DUF2781 PF10914.8 KKK17499.1 - 2.1 8.8 8.5 0.18 12.2 1.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2781) RNA_pol_Rpb2_6 PF00562.28 KKK17500.1 - 5.5e-124 414.2 1.8 6e-124 414.1 0.1 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 KKK17500.1 - 4.5e-36 124.3 0.0 9.8e-18 64.4 0.3 2.3 1 1 1 2 2 2 2 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.20 KKK17500.1 - 5.3e-33 113.3 0.6 1.4e-32 111.9 0.6 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.14 KKK17500.1 - 2.1e-26 92.8 5.3 4.5e-26 91.7 5.3 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_4 PF04566.13 KKK17500.1 - 1e-23 83.4 1.6 2.4e-23 82.2 0.5 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 KKK17500.1 - 1.4e-19 70.0 0.0 4.1e-19 68.5 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 KKK17500.1 - 1.1e-10 41.9 0.4 3.6e-10 40.3 0.4 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 NRDD PF13597.6 KKK17500.1 - 0.15 10.8 0.2 0.24 10.1 0.2 1.2 1 0 0 1 1 1 0 Anaerobic ribonucleoside-triphosphate reductase adh_short PF00106.25 KKK17501.1 - 6.7e-30 104.0 0.0 8.8e-30 103.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KKK17501.1 - 1.9e-26 93.0 0.0 4.5e-26 91.9 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KKK17501.1 - 0.00069 19.6 0.0 0.0012 18.7 0.0 1.6 1 1 0 1 1 1 1 KR domain ADH_zinc_N PF00107.26 KKK17501.1 - 0.0041 17.1 0.1 0.28 11.1 0.0 2.3 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Epimerase PF01370.21 KKK17501.1 - 0.029 13.8 0.0 0.042 13.3 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.19 KKK17501.1 - 0.12 11.8 0.0 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Abhydrolase_1 PF00561.20 KKK17503.1 - 6.7e-20 71.8 0.1 2.6e-14 53.5 0.1 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KKK17503.1 - 7.6e-10 39.8 0.0 1e-09 39.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 KKK17503.1 - 1.8e-07 31.2 0.3 1.3e-06 28.3 0.3 2.0 1 1 0 1 1 1 1 PGAP1-like protein Hydrolase_4 PF12146.8 KKK17503.1 - 5.1e-07 29.2 0.1 7.4e-07 28.7 0.1 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DUF915 PF06028.11 KKK17503.1 - 0.0012 18.3 0.1 1.9 7.8 0.1 2.8 2 1 0 3 3 3 2 Alpha/beta hydrolase of unknown function (DUF915) Esterase PF00756.20 KKK17503.1 - 0.0013 18.5 0.0 0.0019 17.9 0.0 1.4 1 1 0 1 1 1 1 Putative esterase Thioesterase PF00975.20 KKK17503.1 - 0.0017 18.5 0.0 0.0024 18.0 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Chlorophyllase2 PF12740.7 KKK17503.1 - 0.0019 17.1 0.1 0.0039 16.1 0.1 1.6 1 1 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 KKK17503.1 - 0.0033 16.5 0.0 0.0076 15.3 0.0 1.7 1 1 0 1 1 1 1 Chlorophyllase DUF676 PF05057.14 KKK17503.1 - 0.0088 15.6 0.1 0.013 15.0 0.1 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Ndr PF03096.14 KKK17503.1 - 0.014 14.1 0.0 0.034 12.8 0.0 1.6 2 0 0 2 2 2 0 Ndr family DUF3530 PF12048.8 KKK17503.1 - 0.016 14.7 0.0 0.022 14.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) Abhydrolase_3 PF07859.13 KKK17503.1 - 0.05 13.5 0.0 0.12 12.2 0.0 1.7 1 1 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_5 PF12695.7 KKK17503.1 - 0.065 13.0 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 KKK17503.1 - 0.099 12.4 0.0 11 5.7 0.0 2.3 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Lipase_3 PF01764.25 KKK17503.1 - 0.1 12.4 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DUF2048 PF09752.9 KKK17503.1 - 0.14 11.2 0.0 0.35 9.9 0.0 1.6 2 0 0 2 2 2 0 Abhydrolase domain containing 18 LCAT PF02450.15 KKK17503.1 - 0.22 10.7 0.1 0.31 10.2 0.1 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase GYF PF02213.16 KKK17504.1 - 3.6e-13 49.0 1.1 9.5e-13 47.6 1.1 1.7 1 0 0 1 1 1 1 GYF domain HBS1_N PF08938.10 KKK17504.1 - 0.039 14.2 3.6 0.17 12.2 3.6 2.1 1 0 0 1 1 1 0 HBS1 N-terminus UFD1 PF03152.14 KKK17505.1 - 6.2e-75 250.4 0.0 7.7e-75 250.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 Oxidored_FMN PF00724.20 KKK17506.1 - 2.2e-58 198.2 0.0 5.7e-57 193.5 0.0 2.1 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Ribosomal_L3 PF00297.22 KKK17531.1 - 7.2e-185 614.2 12.3 9.4e-185 613.9 12.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L3 TPR_1 PF00515.28 KKK17531.1 - 1.6e-50 166.9 21.8 8.4e-08 31.7 0.1 10.8 11 1 0 11 11 11 9 Tetratricopeptide repeat TPR_2 PF07719.17 KKK17531.1 - 7.8e-44 144.3 16.6 2e-05 24.3 0.0 10.7 11 0 0 11 11 10 9 Tetratricopeptide repeat TPR_8 PF13181.6 KKK17531.1 - 1.4e-36 121.7 15.2 3.3e-06 26.9 0.0 10.8 10 1 0 10 10 10 9 Tetratricopeptide repeat TPR_11 PF13414.6 KKK17531.1 - 2.1e-24 84.9 19.3 2.6e-05 23.8 1.0 9.6 6 2 3 9 9 9 7 TPR repeat TPR_17 PF13431.6 KKK17531.1 - 4.4e-24 83.1 13.5 0.003 17.8 0.1 9.6 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_14 PF13428.6 KKK17531.1 - 5.1e-23 79.8 15.6 9.3e-05 22.9 0.0 9.2 4 3 6 10 10 10 7 Tetratricopeptide repeat TPR_19 PF14559.6 KKK17531.1 - 1.2e-21 77.0 12.7 0.0016 18.9 0.0 7.0 4 2 3 7 7 7 6 Tetratricopeptide repeat TPR_16 PF13432.6 KKK17531.1 - 7.7e-21 74.5 14.4 0.00019 22.0 0.0 7.7 5 2 1 7 7 7 5 Tetratricopeptide repeat TPR_12 PF13424.6 KKK17531.1 - 2.7e-20 72.4 19.6 0.0002 21.6 0.7 7.7 3 2 3 7 7 7 4 Tetratricopeptide repeat TPR_7 PF13176.6 KKK17531.1 - 2.5e-18 64.7 10.9 0.045 13.8 0.1 9.5 9 1 0 9 9 9 4 Tetratricopeptide repeat TPR_6 PF13174.6 KKK17531.1 - 4.3e-17 61.5 15.4 0.014 16.0 0.0 9.6 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_9 PF13371.6 KKK17531.1 - 1.5e-14 53.9 9.9 0.0046 17.1 0.0 6.9 1 1 6 8 8 8 5 Tetratricopeptide repeat ANAPC3 PF12895.7 KKK17531.1 - 7.9e-13 48.4 7.2 1.2e-07 31.9 2.8 3.7 3 0 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 KKK17531.1 - 3.7e-06 26.4 14.9 0.035 13.3 0.7 5.5 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_21 PF09976.9 KKK17531.1 - 1.4e-05 24.9 2.8 0.32 10.7 0.0 4.5 2 2 2 4 4 4 2 Tetratricopeptide repeat-like domain BTAD PF03704.17 KKK17531.1 - 0.00011 22.6 6.8 0.078 13.4 0.1 3.6 3 0 0 3 3 3 2 Bacterial transcriptional activator domain TPR_MalT PF17874.1 KKK17531.1 - 0.011 15.1 8.5 0.14 11.5 0.0 3.5 2 2 1 3 3 3 0 MalT-like TPR region TPR_10 PF13374.6 KKK17531.1 - 0.07 13.0 10.8 44 4.1 0.2 6.3 7 0 0 7 7 5 0 Tetratricopeptide repeat TPR_20 PF14561.6 KKK17531.1 - 0.1 12.9 0.3 3.5 8.0 0.0 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat DUF2225 PF09986.9 KKK17531.1 - 0.11 12.1 4.4 1.8 8.3 0.0 3.2 3 1 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2225) zinc_ribbon_15 PF17032.5 KKK17533.1 - 0.00066 20.4 0.2 0.097 13.4 0.0 2.3 2 0 0 2 2 2 1 zinc-ribbon family zf-DNA_Pol PF08996.10 KKK17533.1 - 0.025 14.3 2.7 3.1 7.5 0.2 2.2 2 0 0 2 2 2 0 DNA Polymerase alpha zinc finger DZR PF12773.7 KKK17533.1 - 0.14 12.2 7.6 2.1 8.4 1.0 2.6 2 1 0 2 2 2 0 Double zinc ribbon CENP-B_dimeris PF09026.10 KKK17533.1 - 0.14 12.5 0.3 0.29 11.5 0.3 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain C1_1 PF00130.22 KKK17533.1 - 0.23 11.4 3.1 4.2 7.3 0.3 2.9 2 1 1 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) p450 PF00067.22 KKK17534.1 - 5.1e-72 243.1 0.0 5.7e-72 242.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF3295 PF11702.8 KKK17535.1 - 8.7e-190 632.3 30.0 1e-189 632.1 30.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3295) DUF1752 PF08550.10 KKK17535.1 - 5.2e-12 45.4 2.6 1.3e-11 44.1 2.6 1.8 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) TFIIA PF03153.13 KKK17535.1 - 3.8 7.4 14.3 0.082 12.9 5.8 2.0 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Glyoxalase PF00903.25 KKK17536.1 - 2.1e-08 34.4 0.0 2.7e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 KKK17536.1 - 6.2e-05 23.2 0.0 0.00014 22.1 0.0 1.6 2 0 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Pkinase PF00069.25 KKK17537.1 - 9.6e-30 103.8 0.0 1.1e-28 100.3 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK17537.1 - 4.2e-12 45.9 0.0 9.2e-06 25.1 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase ETF PF01012.21 KKK17538.1 - 1.8e-43 148.5 0.4 2.2e-43 148.3 0.4 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain Ribosomal_L20 PF00453.18 KKK17538.1 - 0.029 14.4 0.0 0.049 13.7 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L20 JAB PF01398.21 KKK17539.1 - 8e-10 38.7 0.0 1.3e-09 38.0 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Flavodoxin_1 PF00258.25 KKK17540.1 - 3.5e-34 118.1 0.0 9e-34 116.7 0.0 1.7 2 0 0 2 2 2 1 Flavodoxin FAD_binding_1 PF00667.20 KKK17540.1 - 1.9e-29 102.8 0.0 3.2e-29 102.1 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 KKK17540.1 - 6.6e-14 52.5 0.0 1.8e-13 51.1 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 KKK17540.1 - 0.0023 18.2 0.4 0.024 14.8 0.1 2.7 2 1 1 3 3 3 2 Flavodoxin domain Flavodoxin_3 PF12641.7 KKK17540.1 - 0.0034 17.1 0.0 0.0089 15.7 0.0 1.6 2 0 0 2 2 2 1 Flavodoxin domain RNA_pol_3_Rpc31 PF11705.8 KKK17541.1 - 8.4e-61 206.1 8.8 1.3e-60 205.5 8.8 1.3 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 SDA1 PF05285.12 KKK17541.1 - 1.3 8.4 9.1 2 7.7 9.1 1.2 1 0 0 1 1 1 0 SDA1 bZIP_1 PF00170.21 KKK17542.1 - 0.00051 20.1 10.4 0.0016 18.5 10.2 1.9 1 1 1 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 KKK17542.1 - 0.024 14.7 6.2 0.024 14.7 6.2 2.1 2 0 0 2 2 2 0 Basic region leucine zipper eIF-3_zeta PF05091.12 KKK17543.1 - 5.1e-208 692.3 0.0 6.3e-208 692.0 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) CPSF100_C PF13299.6 KKK17544.1 - 0.17 12.1 3.7 0.33 11.1 3.7 1.4 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal PcfK PF14058.6 KKK17544.1 - 1.8 8.9 8.3 3.8 7.8 8.3 1.5 1 0 0 1 1 1 0 PcfK-like protein DUF3915 PF13054.6 KKK17544.1 - 2.5 8.1 4.3 42 4.1 1.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3915) DUF1840 PF08895.11 KKK17544.1 - 8.5 6.8 6.8 48 4.4 3.5 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) PAT1 PF09770.9 KKK17544.1 - 8.8 4.4 10.0 11 4.2 10.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SNF2_N PF00176.23 KKK17545.1 - 1.7e-66 224.3 0.1 3.1e-64 216.9 0.1 3.0 1 1 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.15 KKK17545.1 - 2e-05 24.6 0.0 2e-05 24.6 0.0 3.3 2 2 0 2 2 2 1 Type III restriction enzyme, res subunit ToxN_toxin PF13958.6 KKK17546.1 - 0.11 12.7 3.3 0.48 10.7 3.3 2.2 1 0 0 1 1 1 0 Toxin ToxN, type III toxin-antitoxin system ESSS PF10183.9 KKK17547.1 - 0.0019 18.4 0.2 0.011 15.9 0.0 2.0 1 1 1 2 2 2 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) DctM PF06808.12 KKK17547.1 - 0.029 13.2 0.4 0.044 12.6 0.4 1.2 1 0 0 1 1 1 0 Tripartite ATP-independent periplasmic transporter, DctM component Amnionless PF14828.6 KKK17547.1 - 0.075 11.9 0.0 0.084 11.7 0.0 1.1 1 0 0 1 1 1 0 Amnionless DUF2076 PF09849.9 KKK17547.1 - 0.21 11.6 0.0 0.23 11.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Insulin_TMD PF17870.1 KKK17547.1 - 0.26 11.4 0.9 0.55 10.3 0.5 1.7 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment Ribosomal_L33 PF00471.20 KKK17548.1 - 7.9e-06 26.2 0.1 9.6e-06 26.0 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L33 Dicty_REP PF05086.12 KKK17549.1 - 0.00087 17.4 0.2 0.001 17.2 0.2 1.1 1 0 0 1 1 1 1 Dictyostelium (Slime Mold) REP protein Mid2 PF04478.12 KKK17549.1 - 0.0019 18.0 3.4 0.0041 16.9 3.4 1.6 1 1 0 1 1 1 1 Mid2 like cell wall stress sensor Podoplanin PF05808.11 KKK17549.1 - 0.0034 17.5 4.1 0.0034 17.5 4.1 1.6 2 0 0 2 2 2 1 Podoplanin TMEM154 PF15102.6 KKK17549.1 - 0.008 16.1 2.4 0.017 15.1 2.4 1.5 1 0 0 1 1 1 1 TMEM154 protein family Alpha_GJ PF03229.13 KKK17549.1 - 0.0098 16.4 3.3 0.0098 16.4 3.3 1.8 2 0 0 2 2 2 1 Alphavirus glycoprotein J Rax2 PF12768.7 KKK17549.1 - 0.01 15.3 0.9 0.024 14.1 0.0 1.9 1 1 1 2 2 2 1 Cortical protein marker for cell polarity DUF5305 PF17231.2 KKK17549.1 - 0.018 14.4 0.5 0.027 13.9 0.5 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5305) PRR18 PF15671.5 KKK17549.1 - 0.019 14.8 4.4 0.027 14.4 4.4 1.2 1 0 0 1 1 1 0 Proline-rich protein family 18 MGC-24 PF05283.11 KKK17549.1 - 0.024 15.1 4.3 0.024 15.1 4.3 1.8 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Tox-GHH PF15636.6 KKK17549.1 - 0.049 13.6 0.1 0.13 12.3 0.1 1.6 1 0 0 1 1 1 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin SKG6 PF08693.10 KKK17549.1 - 0.058 12.8 0.2 0.058 12.8 0.2 2.9 2 1 1 3 3 2 0 Transmembrane alpha-helix domain AJAP1_PANP_C PF15298.6 KKK17549.1 - 0.17 12.1 10.3 0.27 11.4 10.3 1.3 1 0 0 1 1 1 0 AJAP1/PANP C-terminus Mucin PF01456.17 KKK17549.1 - 0.23 11.4 27.2 0.48 10.4 24.3 2.1 2 0 0 2 2 2 0 Mucin-like glycoprotein SSP160 PF06933.11 KKK17549.1 - 0.75 7.9 23.1 1.3 7.1 23.1 1.3 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Gly_transf_sug PF04488.15 KKK17551.1 - 5.5e-11 43.0 0.0 9.7e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 KKK17551.1 - 0.0015 18.0 0.0 0.0022 17.4 0.0 1.2 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein IMUP PF15761.5 KKK17551.1 - 0.036 14.8 1.8 0.061 14.0 1.8 1.3 1 0 0 1 1 1 0 Immortalisation up-regulated protein PAN_3 PF08277.12 KKK17552.1 - 0.14 12.0 0.1 0.33 10.8 0.1 1.6 1 0 0 1 1 1 0 PAN-like domain Ribonuc_L-PSP PF01042.21 KKK17553.1 - 1.6e-21 76.5 0.0 2e-21 76.2 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP AAA_lid_9 PF17871.1 KKK17553.1 - 0.16 11.9 1.0 0.32 11.0 0.0 1.9 3 0 0 3 3 3 0 AAA lid domain Cellulase PF00150.18 KKK17554.1 - 6.9e-07 29.0 1.1 1.5e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) TMEM154 PF15102.6 KKK17554.1 - 0.0032 17.4 0.1 0.012 15.6 0.1 1.9 1 0 0 1 1 1 1 TMEM154 protein family DUF5385 PF17359.2 KKK17554.1 - 0.042 13.4 0.1 0.042 13.4 0.1 2.6 3 0 0 3 3 3 0 Family of unknown function (DUF5385) EphA2_TM PF14575.6 KKK17554.1 - 0.044 14.7 0.0 0.044 14.7 0.0 2.5 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain CbiN PF02553.15 KKK17554.1 - 0.076 13.0 0.1 0.24 11.4 0.1 1.8 2 0 0 2 2 2 0 Cobalt transport protein component CbiN ODV-E18 PF10717.9 KKK17554.1 - 0.44 10.4 3.2 1.1 9.2 3.2 1.6 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 zf-C2H2_4 PF13894.6 KKK17573.1 - 1.8e-08 34.5 28.0 0.11 13.4 0.2 6.9 7 0 0 7 7 7 3 C2H2-type zinc finger zf-C2H2 PF00096.26 KKK17573.1 - 0.0002 21.6 26.0 3.2 8.4 0.1 6.5 6 0 0 6 6 6 4 Zinc finger, C2H2 type zf-met PF12874.7 KKK17573.1 - 0.0024 18.2 18.6 0.34 11.4 0.0 5.8 6 0 0 6 6 6 2 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 KKK17573.1 - 0.003 17.9 21.8 0.053 13.9 5.9 3.7 1 1 3 4 4 4 2 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 KKK17573.1 - 0.19 12.0 24.2 7.7 6.9 0.9 5.9 5 1 1 6 6 6 0 Zinc-finger double-stranded RNA-binding Zn_ribbon_SprT PF17283.2 KKK17573.1 - 0.76 9.7 0.1 0.76 9.7 0.1 5.1 5 1 0 5 5 5 0 SprT-like zinc ribbon domain zf-MYST PF17772.1 KKK17573.1 - 2.1 8.0 6.7 3.9 7.2 0.1 3.4 3 1 1 4 4 4 0 MYST family zinc finger domain zf_UBZ PF18439.1 KKK17573.1 - 3 7.5 16.1 13 5.5 0.3 4.9 5 0 0 5 5 5 0 Ubiquitin-Binding Zinc Finger zf-H2C2_2 PF13465.6 KKK17573.1 - 3.5 8.2 26.2 1.7 9.2 0.1 5.8 5 1 1 6 6 6 0 Zinc-finger double domain zf-C2H2_6 PF13912.6 KKK17573.1 - 3.7 7.6 11.1 0.26 11.3 0.6 3.7 3 0 0 3 3 3 0 C2H2-type zinc finger zf-NADH-PPase PF09297.11 KKK17573.1 - 4 7.2 0.0 4 7.2 0.0 4.7 5 0 0 5 5 5 0 NADH pyrophosphatase zinc ribbon domain C1_4 PF07975.12 KKK17573.1 - 4.1 7.7 26.2 17 5.8 0.2 5.4 2 1 2 5 5 5 0 TFIIH C1-like domain PHD_4 PF16866.5 KKK17573.1 - 7.4 6.7 17.4 1.9 8.6 1.5 3.9 2 1 1 3 3 3 0 PHD-finger DUF2205 PF10224.9 KKK17590.1 - 9.9e-34 115.2 2.0 9.9e-34 115.2 2.0 1.6 2 0 0 2 2 2 1 Short coiled-coil protein bZIP_1 PF00170.21 KKK17590.1 - 0.0063 16.6 1.7 0.012 15.7 1.7 1.5 1 0 0 1 1 1 1 bZIP transcription factor Spectrin PF00435.21 KKK17590.1 - 0.0097 16.4 1.1 0.015 15.7 1.1 1.3 1 0 0 1 1 1 1 Spectrin repeat DUF2884 PF11101.8 KKK17590.1 - 0.02 14.4 1.2 0.027 14.0 1.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2884) YabA PF06156.13 KKK17590.1 - 0.02 15.5 2.1 0.031 14.9 2.1 1.3 1 0 0 1 1 1 0 Initiation control protein YabA DivIC PF04977.15 KKK17590.1 - 0.025 14.3 1.2 0.04 13.7 1.2 1.3 1 0 0 1 1 1 0 Septum formation initiator HALZ PF02183.18 KKK17590.1 - 0.044 14.0 4.5 0.16 12.2 0.3 2.3 1 1 1 2 2 2 0 Homeobox associated leucine zipper VLPT PF07122.11 KKK17590.1 - 0.054 13.2 0.2 0.15 11.8 0.2 1.7 1 0 0 1 1 1 0 Variable length PCR target protein (VLPT) DUF3450 PF11932.8 KKK17590.1 - 0.072 12.4 3.6 0.09 12.1 3.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) CCDC106 PF15794.5 KKK17590.1 - 0.11 12.1 5.6 0.49 10.1 1.3 2.1 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 LCD1 PF09798.9 KKK17590.1 - 0.14 10.6 4.1 0.17 10.4 4.1 1.0 1 0 0 1 1 1 0 DNA damage checkpoint protein DUF5320 PF17253.2 KKK17590.1 - 0.2 12.7 2.9 0.36 11.9 1.9 2.0 1 1 1 2 2 2 0 Family of unknown function (DUF5320) AMP-binding PF00501.28 KKK17593.1 - 5.6e-72 242.6 0.0 6.8e-72 242.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 KKK17593.1 - 6.3e-19 67.6 0.6 3e-17 62.2 0.2 2.6 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 KKK17593.1 - 2.8e-14 53.8 0.1 9.3e-14 52.2 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain HTH_DeoR PF08220.12 KKK17593.1 - 0.089 12.6 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain GPP34 PF05719.11 KKK17593.1 - 0.1 12.6 0.1 0.22 11.5 0.1 1.5 1 0 0 1 1 1 0 Golgi phosphoprotein 3 (GPP34) Amidase PF01425.21 KKK17594.1 - 2.6e-99 333.3 0.0 3e-99 333.0 0.0 1.1 1 0 0 1 1 1 1 Amidase EAP30 PF04157.16 KKK17595.1 - 4.7e-42 143.9 0.1 6.1e-42 143.5 0.1 1.1 1 0 0 1 1 1 1 EAP30/Vps36 family Vps36-NZF-N PF16988.5 KKK17595.1 - 3.4e-24 84.0 2.3 3.4e-24 84.0 2.3 2.6 2 1 0 2 2 2 1 Vacuolar protein sorting 36 NZF-N zinc-finger domain Vps36_ESCRT-II PF11605.8 KKK17595.1 - 5.5e-17 61.7 0.0 1.3e-12 47.7 0.0 2.4 2 0 0 2 2 2 2 Vacuolar protein sorting protein 36 Vps36 zf-Sec23_Sec24 PF04810.15 KKK17595.1 - 0.00037 20.5 5.0 0.0037 17.3 0.7 2.5 2 0 0 2 2 2 1 Sec23/Sec24 zinc finger zf-RanBP PF00641.18 KKK17595.1 - 0.12 11.7 12.4 0.22 10.9 0.3 2.6 3 0 0 3 3 3 0 Zn-finger in Ran binding protein and others DZR PF12773.7 KKK17595.1 - 0.46 10.6 3.4 0.69 10.0 0.3 2.3 2 0 0 2 2 2 0 Double zinc ribbon zf-C2H2_4 PF13894.6 KKK17595.1 - 7.2 7.7 5.4 58 4.9 0.3 3.4 2 1 1 3 3 3 0 C2H2-type zinc finger LSM PF01423.22 KKK17616.1 - 6.5e-19 67.4 0.3 8.4e-19 67.0 0.3 1.2 1 0 0 1 1 1 1 LSM domain ATP13 PF12921.7 KKK17617.1 - 2.3e-26 91.9 0.0 5.3e-26 90.7 0.0 1.6 1 0 0 1 1 1 1 Mitochondrial ATPase expression PPR_3 PF13812.6 KKK17617.1 - 0.00013 22.0 0.0 0.0014 18.7 0.0 2.4 2 0 0 2 2 2 1 Pentatricopeptide repeat domain PPR_2 PF13041.6 KKK17617.1 - 0.0038 17.4 0.0 0.57 10.4 0.0 2.9 2 0 0 2 2 2 1 PPR repeat family 4PPT_N PF17837.1 KKK17617.1 - 0.1 12.7 0.0 2.5 8.3 0.0 2.8 2 0 0 2 2 2 0 4'-phosphopantetheinyl transferase N-terminal domain PIG-L PF02585.17 KKK17618.1 - 6.5e-27 94.7 0.0 8.8e-27 94.3 0.0 1.2 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase Glyco_hydro_16 PF00722.21 KKK17619.1 - 7.8e-36 123.2 3.7 1.3e-35 122.4 3.7 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 SH3_9 PF14604.6 KKK17621.1 - 4.1e-15 55.4 0.1 6.9e-15 54.6 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KKK17621.1 - 2.9e-13 49.2 0.1 5e-13 48.4 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KKK17621.1 - 5.6e-11 41.9 0.0 1e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain DUF3439 PF11921.8 KKK17621.1 - 1 9.3 6.6 9 6.3 5.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) RTC PF01137.21 KKK17622.1 - 2.6e-49 167.4 0.0 3.4e-49 167.0 0.0 1.1 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase CDPS PF16715.5 KKK17622.1 - 0.18 11.4 0.0 0.29 10.7 0.0 1.3 1 0 0 1 1 1 0 Cyclodipeptide synthase EthD PF07110.11 KKK17624.1 - 3.1e-22 79.5 1.1 3.6e-22 79.3 1.1 1.1 1 0 0 1 1 1 1 EthD domain MmlI PF09448.10 KKK17624.1 - 0.013 16.0 0.1 0.017 15.5 0.1 1.2 1 0 0 1 1 1 0 Methylmuconolactone methyl-isomerase Myb_DNA-bind_6 PF13921.6 KKK17625.1 - 4.8e-05 23.5 0.9 0.0076 16.5 0.2 2.6 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KKK17625.1 - 9.8e-05 22.5 8.0 0.0069 16.6 0.2 3.0 3 0 0 3 3 3 2 Myb-like DNA-binding domain RXT2_N PF08595.11 KKK17625.1 - 0.023 14.7 2.6 0.034 14.2 2.6 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal NOA36 PF06524.12 KKK17625.1 - 0.049 13.0 5.2 0.061 12.6 5.2 1.1 1 0 0 1 1 1 0 NOA36 protein SURF2 PF05477.11 KKK17625.1 - 0.068 12.9 1.6 0.095 12.4 1.6 1.2 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) RNase_H2_suC PF08615.11 KKK17625.1 - 0.077 13.2 0.6 0.086 13.0 0.6 1.1 1 0 0 1 1 1 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) PBP1_TM PF14812.6 KKK17625.1 - 0.14 12.5 4.9 0.29 11.5 4.9 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CENP-B_dimeris PF09026.10 KKK17625.1 - 0.22 11.9 9.8 0.4 11.1 9.8 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain FAM176 PF14851.6 KKK17625.1 - 0.3 10.7 3.3 0.44 10.2 3.3 1.3 1 0 0 1 1 1 0 FAM176 family DUF4611 PF15387.6 KKK17625.1 - 0.82 9.9 7.4 1.4 9.2 7.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) DNA_pol_phi PF04931.13 KKK17625.1 - 2.3 6.2 8.3 2.8 5.9 8.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi Glyco_hydro_17 PF00332.18 KKK17626.1 - 2.7e-34 119.2 1.7 2.1e-33 116.3 1.7 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 PAM2 PF07145.15 KKK17627.1 - 3.8e-05 23.1 7.7 0.054 13.2 0.0 4.8 5 0 0 5 5 5 3 Ataxin-2 C-terminal region NICE-3 PF07406.11 KKK17627.1 - 0.25 11.3 3.8 0.16 12.0 0.7 2.2 2 0 0 2 2 2 0 NICE-3 protein SUR7 PF06687.12 KKK17642.1 - 1.2e-27 97.0 9.1 1.6e-27 96.6 9.1 1.1 1 0 0 1 1 1 1 SUR7/PalI family SCIMP PF15050.6 KKK17642.1 - 0.0079 16.6 0.0 0.031 14.7 0.0 2.0 2 0 0 2 2 2 1 SCIMP protein DUF4381 PF14316.6 KKK17642.1 - 5.7 7.2 6.9 0.33 11.2 0.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) Ribosomal_L34 PF00468.17 KKK17660.1 - 2.2e-16 59.5 11.5 3.5e-16 58.9 11.5 1.3 1 0 0 1 1 1 1 Ribosomal protein L34 LAT PF15234.6 KKK17660.1 - 0.073 12.8 5.5 0.097 12.4 5.5 1.3 1 0 0 1 1 1 0 Linker for activation of T-cells Peptidase_M48_N PF16491.5 KKK17661.1 - 1.5e-65 220.5 6.1 1.5e-65 220.5 6.1 1.8 2 0 0 2 2 2 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M48 PF01435.18 KKK17661.1 - 4.3e-46 157.2 0.7 6.6e-46 156.6 0.0 1.6 2 0 0 2 2 2 1 Peptidase family M48 DUF4538 PF15061.6 KKK17661.1 - 0.033 13.9 1.5 0.033 13.9 1.5 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4538) Peptidase_M56 PF05569.11 KKK17661.1 - 0.076 12.2 1.7 0.13 11.5 0.7 1.8 2 1 0 2 2 2 0 BlaR1 peptidase M56 DUF3381 PF11861.8 KKK17662.1 - 0.013 15.3 9.2 0.016 15.0 9.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) EF-hand_5 PF13202.6 KKK17662.1 - 0.13 11.8 0.2 0.26 10.9 0.2 1.5 1 0 0 1 1 1 0 EF hand WD40 PF00400.32 KKK17663.1 - 1.2e-49 165.2 22.9 9.3e-07 29.5 0.0 13.4 12 4 0 12 12 12 9 WD domain, G-beta repeat Utp13 PF08625.11 KKK17663.1 - 2.7e-48 163.5 0.1 4.5e-48 162.8 0.1 1.3 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain ANAPC4_WD40 PF12894.7 KKK17663.1 - 1.8e-13 50.6 0.3 0.19 12.0 0.0 6.8 5 2 1 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KKK17663.1 - 1.8e-07 30.2 4.1 0.44 9.1 0.0 5.8 3 3 3 6 6 6 4 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KKK17663.1 - 0.0052 15.8 0.2 4.7 6.1 0.0 4.3 4 1 1 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 KKK17663.1 - 0.11 10.9 0.2 1.5 7.3 0.0 2.2 2 0 0 2 2 2 0 Cytochrome D1 heme domain WD40_like PF17005.5 KKK17663.1 - 0.16 11.2 0.0 75 2.5 0.0 4.0 4 1 0 4 4 4 0 WD40-like domain G-patch_2 PF12656.7 KKK17664.1 - 2e-24 85.4 1.2 4e-24 84.5 0.1 2.2 2 0 0 2 2 2 1 G-patch domain G-patch PF01585.23 KKK17664.1 - 0.00044 20.1 0.2 0.0011 18.8 0.2 1.7 1 0 0 1 1 1 1 G-patch domain MCRS_N PF13325.6 KKK17664.1 - 0.082 12.9 2.4 0.14 12.2 2.4 1.3 1 0 0 1 1 1 0 N-terminal region of micro-spherule protein UCH PF00443.29 KKK17665.1 - 1.4e-23 83.7 0.0 4.1e-23 82.2 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 KKK17665.1 - 7.7e-12 45.4 0.1 1.7e-11 44.2 0.1 1.5 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 KKK17665.1 - 0.096 12.3 0.0 0.23 11.0 0.0 1.8 1 1 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase Myb_DNA-bind_6 PF13921.6 KKK17667.1 - 1.4e-16 60.5 0.2 1.4e-16 60.5 0.2 2.2 2 0 0 2 2 2 1 Myb-like DNA-binding domain HSA PF07529.13 KKK17667.1 - 1.9e-13 50.5 0.2 1.9e-13 50.5 0.2 4.1 4 0 0 4 4 4 1 HSA Myb_DNA-binding PF00249.31 KKK17667.1 - 0.00037 20.6 1.7 0.00078 19.6 0.4 2.2 2 0 0 2 2 2 1 Myb-like DNA-binding domain eIF2_C PF09173.11 KKK17668.1 - 1.3e-34 118.3 0.5 3.1e-34 117.1 0.5 1.7 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.27 KKK17668.1 - 7.4e-22 77.8 0.0 3e-21 75.9 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 KKK17668.1 - 7.2e-12 45.5 0.1 1.8e-11 44.2 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 WD40 PF00400.32 KKK17668.1 - 0.00013 22.7 0.0 11 7.1 0.0 5.4 6 0 0 6 6 6 1 WD domain, G-beta repeat MMR_HSR1 PF01926.23 KKK17668.1 - 0.027 14.6 0.0 0.07 13.2 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KKK17668.1 - 0.063 13.2 0.0 0.38 10.6 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase Proteasome PF00227.26 KKK17669.1 - 6.4e-39 133.4 0.0 8.1e-39 133.1 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Sigma54_AID PF00309.20 KKK17669.1 - 0.15 11.9 0.0 0.32 10.9 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 factor, Activator interacting domain (AID) WD40 PF00400.32 KKK17670.1 - 1.8e-19 69.7 8.0 2.4e-06 28.2 0.0 6.0 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKK17670.1 - 0.00033 20.9 0.0 0.0032 17.7 0.0 2.4 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KKK17670.1 - 0.033 13.5 0.0 0.055 12.8 0.0 1.4 1 0 0 1 1 1 0 WD40-like domain Fungal_trans PF04082.18 KKK17671.1 - 0.0022 17.1 0.1 0.0032 16.5 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain WYL_2 PF10902.8 KKK17671.1 - 0.0053 17.1 0.2 0.019 15.3 0.0 1.9 2 0 0 2 2 2 1 WYL_2, Sm-like SH3 beta-barrel fold 2OG-FeII_Oxy_3 PF13640.6 KKK17672.1 - 1.5e-13 51.4 0.0 5.3e-13 49.7 0.0 1.9 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily zf-H2C2_2 PF13465.6 KKK17673.1 - 2e-05 24.8 6.4 2.9e-05 24.3 3.3 2.5 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2 PF00096.26 KKK17673.1 - 2.9e-05 24.2 19.5 3.6e-05 24.0 2.8 3.4 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KKK17673.1 - 0.00012 22.6 1.7 0.00012 22.6 1.7 3.2 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KKK17673.1 - 0.0016 18.6 0.7 0.0041 17.4 0.7 1.7 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KKK17673.1 - 0.0039 17.1 1.3 0.0089 16.0 1.3 1.6 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_8 PF15909.5 KKK17673.1 - 0.035 14.4 4.4 0.077 13.3 4.4 1.6 1 0 0 1 1 1 0 C2H2-type zinc ribbon FOXP-CC PF16159.5 KKK17673.1 - 0.17 12.6 10.9 0.31 11.7 1.7 3.7 2 1 2 4 4 4 0 FOXP coiled-coil domain zf-TRAF PF02176.18 KKK17673.1 - 0.73 10.6 8.4 0.21 12.3 2.4 2.3 2 0 0 2 2 2 0 TRAF-type zinc finger adh_short_C2 PF13561.6 KKK17676.1 - 2e-63 214.1 0.2 2.4e-63 213.8 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KKK17676.1 - 2.4e-43 147.9 0.2 2.9e-43 147.6 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KKK17676.1 - 2.8e-13 50.2 0.1 4e-13 49.7 0.1 1.2 1 0 0 1 1 1 1 KR domain FAD_binding_3 PF01494.19 KKK17677.1 - 9.8e-72 242.1 0.0 1.2e-71 241.8 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 KKK17677.1 - 4.3e-34 117.9 0.0 1e-33 116.7 0.0 1.7 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Pyr_redox_2 PF07992.14 KKK17677.1 - 0.0061 15.8 0.0 0.038 13.2 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KKK17677.1 - 0.0079 15.8 0.1 0.45 10.0 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase UDPG_MGDP_dh_N PF03721.14 KKK17677.1 - 0.03 13.9 0.1 0.31 10.6 0.1 2.1 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox PF00070.27 KKK17677.1 - 0.054 14.1 0.0 0.16 12.6 0.0 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GH131_N PF18271.1 KKK17678.1 - 6.7e-58 196.4 0.3 7.7e-58 196.2 0.3 1.0 1 0 0 1 1 1 1 Glycoside hydrolase 131 catalytic N-terminal domain Tannase PF07519.11 KKK17679.1 - 3.2e-96 323.1 0.0 4.6e-96 322.6 0.0 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_1 PF00561.20 KKK17679.1 - 0.021 14.5 0.0 0.067 12.8 0.0 1.7 2 0 0 2 2 2 0 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KKK17679.1 - 0.037 13.5 0.1 2.3 7.6 0.2 2.3 2 0 0 2 2 2 0 Prolyl oligopeptidase family DUF866 PF05907.13 KKK17680.1 - 2.1e-41 141.4 2.8 7.6e-26 90.9 2.0 2.2 1 1 1 2 2 2 2 Eukaryotic protein of unknown function (DUF866) LSM PF01423.22 KKK17680.1 - 1.7e-16 59.7 0.1 2.7e-16 59.0 0.1 1.3 1 0 0 1 1 1 1 LSM domain MFS_1 PF07690.16 KKK17681.1 - 1.6e-25 89.8 54.9 4.5e-25 88.3 32.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KKK17681.1 - 3.2e-07 29.6 9.3 3.2e-07 29.6 9.3 2.8 2 1 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 KKK17681.1 - 1.2e-05 24.0 2.4 2.5e-05 22.9 2.4 1.5 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) CPP1-like PF11833.8 KKK17681.1 - 9.7 5.8 6.0 22 4.6 0.7 3.0 2 2 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like TPR_2 PF07719.17 KKK17682.1 - 1.9e-13 49.4 1.9 0.0017 18.3 0.0 5.7 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_1 PF00515.28 KKK17682.1 - 3.7e-11 42.4 2.5 0.00048 19.8 0.0 5.3 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.6 KKK17682.1 - 8.6e-08 31.8 7.5 0.014 15.1 0.0 5.8 6 1 1 7 7 7 2 TPR repeat TPR_14 PF13428.6 KKK17682.1 - 5.5e-06 26.8 11.1 0.84 10.6 0.0 7.3 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_19 PF14559.6 KKK17682.1 - 3e-05 24.5 7.1 4.9 7.8 0.0 5.8 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.6 KKK17682.1 - 8.8e-05 23.1 17.4 0.87 10.3 0.0 6.4 7 1 0 7 7 7 3 Tetratricopeptide repeat TPR_8 PF13181.6 KKK17682.1 - 0.00059 19.9 0.5 21 5.6 0.0 5.9 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_12 PF13424.6 KKK17682.1 - 0.00072 19.8 6.7 0.032 14.5 0.2 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 KKK17682.1 - 0.002 18.0 2.6 30 5.0 0.0 5.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_9 PF13371.6 KKK17682.1 - 0.029 14.5 2.5 23 5.2 0.0 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_4 PF07721.14 KKK17682.1 - 0.096 13.4 13.6 0.77 10.6 0.3 6.2 8 0 0 8 8 5 0 Tetratricopeptide repeat p450 PF00067.22 KKK17683.1 - 4.3e-75 253.2 0.0 8.1e-75 252.3 0.0 1.4 2 0 0 2 2 2 1 Cytochrome P450 DRMBL PF07522.14 KKK17683.1 - 4.6e-35 120.1 0.0 1.1e-34 118.9 0.0 1.7 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Zn_clus PF00172.18 KKK17684.1 - 9.8e-09 35.2 7.3 4.5e-08 33.1 7.3 2.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain OPT PF03169.15 KKK17685.1 - 7.2e-172 573.2 51.9 3.3e-169 564.4 45.6 2.0 1 1 1 2 2 2 2 OPT oligopeptide transporter protein NADH_B2 PF14813.6 KKK17685.1 - 0.28 11.0 7.4 7.4 6.4 0.1 3.6 3 0 0 3 3 3 0 NADH dehydrogenase 1 beta subcomplex subunit 2 Citrate_synt PF00285.21 KKK17686.1 - 3.1e-80 270.0 0.0 5.8e-80 269.1 0.0 1.4 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain MFS_1 PF07690.16 KKK17686.1 - 7.1e-45 153.5 24.7 8.7e-45 153.2 21.9 2.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KKK17686.1 - 5.9e-10 38.6 6.6 5.9e-10 38.6 6.6 1.9 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KKK17686.1 - 3.6e-05 22.4 2.9 3.6e-05 22.4 2.9 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_5 PF05631.14 KKK17686.1 - 0.097 11.6 4.9 0.08 11.8 2.2 2.0 2 0 0 2 2 2 0 Sugar-tranasporters, 12 TM CPP1-like PF11833.8 KKK17686.1 - 1.2 8.8 3.7 26 4.4 4.1 2.5 2 0 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like GFA PF04828.14 KKK17687.1 - 2.8e-21 75.6 0.0 4.2e-21 75.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme DZR PF12773.7 KKK17687.1 - 0.15 12.1 5.0 0.88 9.7 0.2 2.6 2 1 0 2 2 2 0 Double zinc ribbon Nudix_N_2 PF14803.6 KKK17687.1 - 0.31 11.0 4.1 0.41 10.6 0.0 2.9 3 0 0 3 3 3 0 Nudix N-terminal PAS_9 PF13426.7 KKK17688.1 - 5.3e-15 55.5 0.1 5.3e-13 49.1 0.0 2.9 3 0 0 3 3 3 1 PAS domain PAS_4 PF08448.10 KKK17688.1 - 0.00012 22.3 0.9 0.3 11.4 0.0 3.2 3 0 0 3 3 3 2 PAS fold SUIM_assoc PF16619.5 KKK17688.1 - 0.00036 20.5 1.0 0.00036 20.5 1.0 2.6 2 0 0 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 PAS PF00989.25 KKK17688.1 - 0.0011 18.9 0.0 0.0011 18.9 0.0 3.5 4 0 0 4 4 4 1 PAS fold PAS_3 PF08447.12 KKK17688.1 - 0.01 16.1 0.1 0.46 10.8 0.0 2.7 2 0 0 2 2 2 0 PAS fold Lin-8 PF03353.15 KKK17688.1 - 0.11 12.1 10.6 2.9 7.4 9.3 2.2 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist TFIIA PF03153.13 KKK17688.1 - 0.11 12.5 14.4 0.17 11.8 14.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit BAF1_ABF1 PF04684.13 KKK17688.1 - 0.13 11.3 9.6 0.21 10.6 9.6 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Spt20 PF12090.8 KKK17688.1 - 0.17 11.5 14.3 0.34 10.5 14.3 1.4 1 0 0 1 1 1 0 Spt20 family ASD2 PF08687.11 KKK17688.1 - 0.6 9.6 11.6 1.2 8.6 11.6 1.4 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 O-antigen_lig PF13425.6 KKK17688.1 - 0.94 8.2 6.6 1.3 7.7 6.6 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein FGF-BP1 PF06473.12 KKK17688.1 - 2.5 7.9 11.0 4.4 7.1 11.0 1.3 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) Rtf2 PF04641.12 KKK17688.1 - 2.7 7.3 8.0 5.2 6.3 8.0 1.4 1 0 0 1 1 1 0 Rtf2 RING-finger Presenilin PF01080.17 KKK17688.1 - 7.6 5.2 13.5 5.5 5.7 10.7 1.8 2 0 0 2 2 2 0 Presenilin ATG22 PF11700.8 KKK17689.1 - 2.5e-182 606.8 12.0 2.9e-182 606.6 12.0 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_2 PF13347.6 KKK17689.1 - 1.7e-07 30.2 24.6 1.1e-05 24.2 10.9 2.4 2 0 0 2 2 2 2 MFS/sugar transport protein MFS_1 PF07690.16 KKK17689.1 - 6.7e-05 22.0 22.6 6.7e-05 22.0 22.6 3.2 2 1 1 3 3 3 2 Major Facilitator Superfamily BT1 PF03092.16 KKK17689.1 - 2.7 6.1 10.3 0.042 12.1 2.0 2.1 2 0 0 2 2 2 0 BT1 family Zn_clus PF00172.18 KKK17690.1 - 5.4e-08 32.8 11.0 5.4e-08 32.8 11.0 2.3 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PBP PF01161.20 KKK17691.1 - 3.9e-11 43.4 0.1 5.1e-11 43.0 0.1 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Mucin PF01456.17 KKK17691.1 - 0.09 12.8 19.7 0.12 12.3 19.7 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein PBP PF01161.20 KKK17692.1 - 8.7e-20 71.4 0.0 1.1e-19 71.0 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein 14-3-3 PF00244.20 KKK17694.1 - 1.8e-101 338.3 4.6 2.1e-101 338.1 4.6 1.0 1 0 0 1 1 1 1 14-3-3 protein Orbi_VP5 PF00901.17 KKK17694.1 - 0.12 10.8 3.1 0.17 10.2 3.1 1.2 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 IATP PF04568.12 KKK17695.1 - 1.4e-27 96.0 1.1 1.6e-27 95.8 1.1 1.0 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP PKHD_C PF18331.1 KKK17695.1 - 0.11 12.6 0.2 0.18 11.9 0.2 1.4 1 0 0 1 1 1 0 PKHD-type hydroxylase C-terminal domain zf-MIZ PF02891.20 KKK17696.1 - 9.2e-12 44.5 0.2 1.7e-11 43.7 0.2 1.4 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 KKK17696.1 - 0.0009 19.0 0.1 0.0019 18.0 0.1 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Nsp1_C PF05064.13 KKK17697.1 - 3.5e-43 146.1 1.2 9.4e-43 144.7 1.2 1.6 1 0 0 1 1 1 1 Nsp1-like C-terminal region Nucleoporin_FG PF13634.6 KKK17697.1 - 6.1e-08 33.4 154.8 2.8e-06 28.1 24.8 7.3 1 1 3 4 4 2 2 Nucleoporin FG repeat region Snapin_Pallidin PF14712.6 KKK17697.1 - 0.13 12.7 4.2 3.4 8.2 0.1 2.5 3 0 0 3 3 2 0 Snapin/Pallidin TACC_C PF05010.14 KKK17697.1 - 0.17 11.7 6.7 2.8 7.7 6.6 2.1 1 1 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal BLOC1_2 PF10046.9 KKK17697.1 - 0.2 12.0 5.6 1 9.7 0.2 2.4 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1664 PF07889.12 KKK17697.1 - 0.27 11.3 5.3 3.2 7.8 0.3 2.6 2 1 0 3 3 3 0 Protein of unknown function (DUF1664) CREPT PF16566.5 KKK17697.1 - 0.41 10.8 4.9 11 6.2 0.1 2.3 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour Laminin_II PF06009.12 KKK17697.1 - 0.46 10.5 5.7 3.9 7.5 0.6 2.6 2 1 0 2 2 2 0 Laminin Domain II DUF724 PF05266.14 KKK17697.1 - 1.5 8.6 7.5 2.4 7.9 1.9 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF724) FapA PF03961.13 KKK17697.1 - 2 6.9 4.4 3.5 6.1 0.4 2.0 1 1 1 2 2 2 0 Flagellar Assembly Protein A DUF16 PF01519.16 KKK17697.1 - 3.4 8.2 5.6 7.3 7.1 0.1 2.6 1 1 2 3 3 3 0 Protein of unknown function DUF16 HIP1_clath_bdg PF16515.5 KKK17697.1 - 3.6 8.2 11.9 3.3 8.4 3.9 2.9 1 1 3 4 4 4 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Spc7 PF08317.11 KKK17697.1 - 3.9 6.3 10.2 0.67 8.8 3.6 2.0 1 1 0 2 2 2 0 Spc7 kinetochore protein IFT57 PF10498.9 KKK17697.1 - 6.2 5.7 10.3 0.58 9.1 4.0 1.9 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 GAS PF13851.6 KKK17697.1 - 7 6.0 8.0 25 4.1 6.4 1.9 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding MscS_porin PF12795.7 KKK17697.1 - 7 6.1 12.0 3.7 7.0 1.8 2.3 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain DUF5102 PF17104.5 KKK17698.1 - 9.6e-109 363.9 2.0 1.4e-108 363.4 2.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF5102) FEZ PF07763.13 KKK17698.1 - 0.006 16.4 0.0 0.36 10.5 0.0 2.2 2 0 0 2 2 2 2 FEZ-like protein NCBP3 PF10309.9 KKK17699.1 - 2.6e-22 78.4 0.0 4.1e-22 77.8 0.0 1.3 1 0 0 1 1 1 1 Nuclear cap-binding protein subunit 3 DUF3439 PF11921.8 KKK17699.1 - 0.16 11.9 0.4 0.42 10.6 0.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Glyco_transf_41 PF13844.6 KKK17700.1 - 7.2e-103 344.5 0.0 7.6e-52 176.3 0.0 3.1 1 1 1 2 2 2 2 Glycosyl transferase family 41 TPR_1 PF00515.28 KKK17700.1 - 3e-18 64.8 10.5 5.7e-05 22.8 0.0 7.0 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_2 PF07719.17 KKK17700.1 - 9.4e-14 50.4 17.8 0.0059 16.6 0.0 6.7 7 0 0 7 7 6 5 Tetratricopeptide repeat TPR_8 PF13181.6 KKK17700.1 - 5.8e-13 48.0 8.4 0.0051 16.9 0.1 6.5 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.6 KKK17700.1 - 1.5e-11 43.7 17.6 0.0001 21.9 0.1 7.2 5 2 3 8 8 8 4 TPR repeat TPR_10 PF13374.6 KKK17700.1 - 2.1e-08 33.7 17.8 0.025 14.4 0.1 6.3 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.6 KKK17700.1 - 8.2e-08 32.4 14.0 0.036 14.9 0.0 6.3 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 KKK17700.1 - 1.1e-07 32.2 10.6 0.0016 18.9 0.7 4.6 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.6 KKK17700.1 - 2.5e-07 30.6 5.4 0.25 11.8 0.2 5.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 KKK17700.1 - 5.9e-07 29.7 16.4 0.15 12.4 0.8 5.6 5 1 0 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 KKK17700.1 - 3.7e-06 27.5 19.9 0.0095 16.6 0.2 5.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 KKK17700.1 - 1.9e-05 24.3 9.3 0.13 12.4 0.0 5.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_15 PF13429.6 KKK17700.1 - 0.0058 15.9 0.4 0.3 10.2 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat BTAD PF03704.17 KKK17700.1 - 0.039 14.4 11.5 0.044 14.2 0.0 4.2 5 0 0 5 5 5 0 Bacterial transcriptional activator domain TPR_9 PF13371.6 KKK17700.1 - 0.05 13.8 0.3 0.05 13.8 0.3 4.1 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 KKK17700.1 - 0.37 11.5 3.4 1.4e+02 3.5 0.0 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF3638 PF12340.8 KKK17701.1 - 2.7e-85 285.3 0.0 5.3e-85 284.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.8 KKK17701.1 - 1.9e-15 55.9 0.0 4.8e-15 54.6 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) Rrf2 PF02082.20 KKK17702.1 - 0.024 15.0 0.0 0.071 13.5 0.0 1.7 1 0 0 1 1 1 0 Transcriptional regulator LacI PF00356.21 KKK17702.1 - 0.16 11.8 0.5 0.59 10.0 0.0 2.2 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family Scytalone_dh PF02982.14 KKK17703.1 - 3.3e-62 209.0 0.6 1.7e-48 164.5 0.2 2.0 2 0 0 2 2 2 2 Scytalone dehydratase SnoaL_4 PF13577.6 KKK17703.1 - 5.4e-05 23.3 0.0 7.8e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain Pkinase PF00069.25 KKK17705.1 - 7.8e-67 225.4 0.0 9.1e-67 225.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK17705.1 - 1e-25 90.5 0.0 1.4e-25 90.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KKK17705.1 - 3.4e-06 26.6 0.0 1.7e-05 24.3 0.0 2.0 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KKK17705.1 - 0.0038 17.2 0.2 0.02 14.8 0.0 2.0 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 KKK17705.1 - 0.16 11.3 0.0 0.25 10.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family MIF4G_like PF09088.11 KKK17706.1 - 9.5e-92 306.0 0.1 1.4e-91 305.4 0.1 1.3 1 0 0 1 1 1 1 MIF4G like MIF4G_like_2 PF09090.11 KKK17706.1 - 3.4e-74 249.7 0.0 5e-74 249.1 0.0 1.3 1 0 0 1 1 1 1 MIF4G like MIF4G PF02854.19 KKK17706.1 - 0.002 17.8 0.2 0.0067 16.1 0.0 1.9 3 0 0 3 3 3 1 MIF4G domain OPT PF03169.15 KKK17707.1 - 1.1e-109 367.8 37.1 1.3e-109 367.6 37.1 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF3130 PF11328.8 KKK17708.1 - 0.04 14.2 0.1 0.19 12.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3130 Pkinase PF00069.25 KKK17716.1 - 3.4e-30 105.3 0.0 3.7e-30 105.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK17716.1 - 8.3e-21 74.4 0.0 9.3e-21 74.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase ABC1 PF03109.16 KKK17716.1 - 0.0082 16.3 0.0 0.012 15.8 0.0 1.3 1 0 0 1 1 1 1 ABC1 family Thioredoxin_7 PF13899.6 KKK17717.1 - 8e-17 61.2 0.0 1.6e-16 60.3 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like UBA_4 PF14555.6 KKK17717.1 - 1.2e-14 53.8 0.1 2.6e-14 52.8 0.1 1.5 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.20 KKK17717.1 - 2.4e-05 24.4 0.1 0.00014 22.0 0.0 2.3 3 0 0 3 3 3 1 UBX domain Thioredoxin_2 PF13098.6 KKK17717.1 - 0.019 15.4 0.0 0.039 14.4 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like domain TAP_C PF03943.13 KKK17717.1 - 0.079 12.6 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 TAP C-terminal domain Thioredox_DsbH PF03190.15 KKK17717.1 - 0.14 12.2 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF255 AAA PF00004.29 KKK17718.1 - 2.4e-13 50.6 0.0 7e-13 49.2 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KKK17718.1 - 4e-12 46.8 0.3 1.8e-11 44.7 0.3 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KKK17718.1 - 5.7e-11 42.8 0.0 1.6e-10 41.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain Cdc6_C PF09079.11 KKK17718.1 - 8.4e-08 32.1 0.1 4.5e-07 29.7 0.1 2.3 1 1 0 1 1 1 1 CDC6, C terminal winged helix domain DUF2075 PF09848.9 KKK17718.1 - 0.00034 20.0 0.0 0.00062 19.1 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_11 PF13086.6 KKK17718.1 - 0.0013 18.6 0.5 0.07 12.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_lid_10 PF17872.1 KKK17718.1 - 0.0014 18.7 0.0 0.003 17.7 0.0 1.4 1 0 0 1 1 1 1 AAA lid domain AAA_7 PF12775.7 KKK17718.1 - 0.0016 18.0 0.0 0.0039 16.7 0.0 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_19 PF13245.6 KKK17718.1 - 0.0047 17.3 0.0 0.0095 16.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 KKK17718.1 - 0.017 14.3 0.0 0.034 13.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) PIF1 PF05970.14 KKK17718.1 - 0.027 13.7 0.0 0.043 13.0 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase TIP49 PF06068.13 KKK17718.1 - 0.03 13.5 0.0 0.057 12.6 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain NTPase_1 PF03266.15 KKK17718.1 - 0.032 14.2 0.0 0.061 13.2 0.0 1.5 1 0 0 1 1 1 0 NTPase ATPase_2 PF01637.18 KKK17718.1 - 0.039 13.9 0.0 0.085 12.8 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea NACHT PF05729.12 KKK17718.1 - 0.043 13.7 0.1 0.11 12.4 0.1 1.7 1 1 0 1 1 1 0 NACHT domain ABC_tran PF00005.27 KKK17718.1 - 0.049 14.1 0.0 0.18 12.3 0.0 2.0 2 0 0 2 2 1 0 ABC transporter AAA_5 PF07728.14 KKK17718.1 - 0.075 13.0 0.0 0.22 11.5 0.0 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 KKK17718.1 - 0.11 12.7 0.0 0.35 11.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KKK17718.1 - 0.11 12.8 0.0 0.45 10.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 KKK17718.1 - 0.13 11.4 0.0 0.24 10.5 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain SLAC1 PF03595.17 KKK17759.1 - 1.4e-97 326.8 54.4 1.6e-97 326.7 54.4 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel Glyco_hydro_28 PF00295.17 KKK17760.1 - 2.1e-28 99.4 4.1 2.1e-28 99.4 4.1 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 28 Pectate_lyase_3 PF12708.7 KKK17760.1 - 3.8e-10 40.0 4.3 3.8e-10 40.0 4.3 3.3 2 1 1 3 3 3 1 Pectate lyase superfamily protein SAP130_C PF16014.5 KKK17760.1 - 9.7 5.2 8.8 13 4.7 8.8 1.2 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP130 C-terminus MFS_1 PF07690.16 KKK17761.1 - 4.2e-23 81.9 39.9 2.9e-12 46.2 22.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KKK17761.1 - 7.9e-14 51.4 17.9 3.5e-12 45.9 2.4 2.6 1 1 0 2 2 2 2 Sugar (and other) transporter Fungal_trans PF04082.18 KKK17762.1 - 1.4e-29 103.0 1.5 7.8e-16 57.9 0.1 2.4 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK17762.1 - 7.6e-16 58.0 27.5 2.7e-09 37.0 11.1 2.6 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Streptin-Immun PF11083.8 KKK17762.1 - 1.4 9.4 2.9 25 5.3 0.3 2.5 2 0 0 2 2 2 0 Lantibiotic streptin immunity protein Glyco_trans_4_4 PF13579.6 KKK17762.1 - 3.8 7.9 7.2 1.6 9.2 2.0 2.5 2 0 0 2 2 2 0 Glycosyl transferase 4-like domain UDPGP PF01704.18 KKK17763.1 - 1.4e-192 639.8 0.1 1.7e-192 639.6 0.1 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase PilO PF04350.13 KKK17763.1 - 0.016 15.4 0.2 0.07 13.3 0.0 2.1 3 0 0 3 3 3 0 Pilus assembly protein, PilO C2 PF00168.30 KKK17764.1 - 6e-74 244.9 0.0 9.6e-18 64.4 0.0 5.6 5 0 0 5 5 5 5 C2 domain SMP_LBD PF17047.5 KKK17764.1 - 0.00029 20.4 0.0 0.00049 19.6 0.0 1.4 1 0 0 1 1 1 1 Synaptotagmin-like mitochondrial-lipid-binding domain FKBP_C PF00254.28 KKK17764.1 - 0.029 14.7 0.0 0.16 12.3 0.0 2.3 1 0 0 1 1 1 0 FKBP-type peptidyl-prolyl cis-trans isomerase DUF3439 PF11921.8 KKK17765.1 - 0.0013 18.6 3.5 0.0022 17.9 3.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3439) ATG16 PF08614.11 KKK17765.1 - 0.023 14.9 1.9 0.023 14.9 1.9 1.8 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) ABC_tran_CTD PF16326.5 KKK17765.1 - 0.03 14.6 4.0 0.087 13.1 1.5 2.2 1 1 0 2 2 2 0 ABC transporter C-terminal domain Dicty_REP PF05086.12 KKK17765.1 - 0.055 11.5 5.1 0.09 10.7 5.1 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Striatin PF08232.12 KKK17765.1 - 0.097 13.3 4.2 0.24 12.0 3.9 1.8 1 1 1 2 2 2 0 Striatin family DUF641 PF04859.12 KKK17765.1 - 0.14 12.5 2.1 0.87 9.9 2.3 2.0 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) SSP160 PF06933.11 KKK17765.1 - 0.91 7.6 9.8 1.2 7.3 9.8 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Leo1 PF04004.13 KKK17766.1 - 4.9e-29 101.3 0.1 1.9e-28 99.4 0.1 1.9 1 1 0 1 1 1 1 Leo1-like protein Zn_clus PF00172.18 KKK17767.1 - 7.8e-09 35.5 8.5 2.3e-08 34.0 8.5 1.9 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain S36_mt PF10937.8 KKK17767.1 - 0.23 13.1 1.3 0.64 11.6 1.3 1.7 1 0 0 1 1 1 0 Ribosomal protein S36, mitochondrial Mob1_phocein PF03637.17 KKK17768.1 - 7.1e-51 172.6 0.7 5.8e-50 169.6 0.7 2.0 1 1 0 1 1 1 1 Mob1/phocein family BOP1NT PF08145.12 KKK17769.1 - 2.3e-105 352.2 6.8 3.3e-105 351.7 6.8 1.2 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.32 KKK17769.1 - 5.8e-24 83.9 5.2 4e-10 40.1 0.1 5.6 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKK17769.1 - 1.2e-06 28.7 0.0 0.0018 18.6 0.0 3.5 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 KKK17769.1 - 0.011 16.2 2.1 3.7 8.1 0.0 3.8 4 0 0 4 4 4 0 PQQ-like domain Npa1 PF11707.8 KKK17770.1 - 3.1e-100 335.9 2.1 3.3e-100 335.8 0.2 2.1 2 0 0 2 2 2 1 Ribosome 60S biogenesis N-terminal NopRA1 PF16201.5 KKK17770.1 - 2.5e-54 183.9 0.6 8.7e-54 182.2 0.0 2.4 4 0 0 4 4 4 1 Nucleolar pre-ribosomal-associated protein 1 Creb_binding PF09030.10 KKK17770.1 - 0.021 15.5 0.1 0.12 13.1 0.0 2.3 2 0 0 2 2 2 0 Creb binding RSN1_7TM PF02714.15 KKK17771.1 - 5.8e-91 304.6 30.6 1.6e-89 299.9 20.0 2.8 3 0 0 3 3 3 2 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 KKK17771.1 - 2.4e-46 157.4 3.9 2.4e-46 157.4 3.9 2.8 4 0 0 4 4 4 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 KKK17771.1 - 2.5e-37 128.8 0.2 4e-37 128.1 0.2 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 KKK17771.1 - 3.6e-32 110.4 0.4 9.5e-32 109.0 0.2 1.8 2 0 0 2 2 2 1 Extracellular tail, of 10TM putative phosphate transporter DUF3493 PF11998.8 KKK17771.1 - 0.99 9.6 6.9 8.3 6.7 0.0 3.2 3 0 0 3 3 3 0 Low psii accumulation1 / Rep27 Orf78 PF06024.12 KKK17771.1 - 1.1 9.6 6.2 21 5.5 0.1 3.3 2 0 0 2 2 2 0 Orf78 (ac78) TMEM154 PF15102.6 KKK17771.1 - 3.5 7.5 8.7 0.43 10.5 0.3 3.0 2 0 0 2 2 2 0 TMEM154 protein family Insulin_TMD PF17870.1 KKK17771.1 - 7.3 6.8 12.9 9.9 6.3 0.1 3.5 3 0 0 3 3 3 0 Insulin receptor trans-membrane segment Sec23_helical PF04815.15 KKK17772.1 - 0.093 12.6 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 Sec23/Sec24 helical domain VHP PF02209.19 KKK17772.1 - 0.1 12.7 0.0 0.26 11.4 0.0 1.7 1 0 0 1 1 1 0 Villin headpiece domain Cation_ATPase_C PF00689.21 KKK17773.1 - 3.5e-20 72.5 7.9 4.1e-20 72.3 7.9 1.0 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Ras PF00071.22 KKK17774.1 - 2e-56 190.1 0.0 2.3e-56 189.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KKK17774.1 - 4.6e-22 78.5 0.0 7.1e-22 77.9 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKK17774.1 - 3.3e-07 29.9 0.0 5.3e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KKK17774.1 - 0.00013 21.6 0.0 0.00034 20.2 0.0 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 KKK17774.1 - 0.0061 16.0 0.0 0.011 15.2 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 KKK17774.1 - 0.048 13.0 0.0 0.061 12.7 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region NB-ARC PF00931.22 KKK17774.1 - 0.054 12.7 0.1 0.52 9.4 0.0 2.0 1 1 1 2 2 2 0 NB-ARC domain PduV-EutP PF10662.9 KKK17774.1 - 0.14 11.9 0.0 24 4.7 0.0 2.7 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation KOW PF00467.29 KKK17775.1 - 0.23 11.5 0.4 0.43 10.6 0.4 1.5 1 0 0 1 1 1 0 KOW motif Mpv17_PMP22 PF04117.12 KKK17776.1 - 5.2e-16 58.6 0.2 5.2e-16 58.6 0.2 2.1 2 0 0 2 2 2 1 Mpv17 / PMP22 family MFS_1 PF07690.16 KKK17777.1 - 8.6e-41 140.0 44.0 8.6e-41 140.0 44.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KKK17777.1 - 7.1e-10 38.3 10.0 7.1e-10 38.3 10.0 2.5 2 2 0 2 2 2 1 Sugar (and other) transporter DUF5379 PF17350.2 KKK17777.1 - 0.2 12.0 0.1 0.2 12.0 0.1 3.3 3 0 0 3 3 3 0 Family of unknown function (DUF5379) PH PF00169.29 KKK17778.1 - 2.4e-08 34.4 0.0 8e-08 32.7 0.0 1.8 1 1 0 1 1 1 1 PH domain Anillin PF08174.11 KKK17778.1 - 1.2e-07 32.2 0.0 2.8e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 Cell division protein anillin DEAD PF00270.29 KKK17779.1 - 7.6e-33 113.7 0.1 1.8e-32 112.5 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KKK17779.1 - 1.4e-19 70.5 0.0 4.5e-18 65.6 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KKK17779.1 - 4.9e-07 29.9 0.0 5e-06 26.6 0.0 2.4 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 KKK17779.1 - 0.0041 15.9 0.0 0.0062 15.3 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Pex16 PF08610.10 KKK17779.1 - 0.086 12.0 0.2 0.2 10.8 0.2 1.6 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) TFIIE_alpha PF02002.17 KKK17780.1 - 2.8e-19 68.9 0.0 6.8e-19 67.7 0.0 1.7 1 0 0 1 1 1 1 TFIIE alpha subunit HTH_Crp_2 PF13545.6 KKK17780.1 - 0.021 14.8 0.2 0.039 13.9 0.2 1.5 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain Zn-ribbon_8 PF09723.10 KKK17780.1 - 0.052 13.7 0.4 0.22 11.7 0.4 2.0 1 1 1 2 2 2 0 Zinc ribbon domain TF_Zn_Ribbon PF08271.12 KKK17780.1 - 0.054 13.0 2.0 0.84 9.2 2.0 2.5 1 1 1 2 2 2 0 TFIIB zinc-binding DUF2462 PF09495.10 KKK17780.1 - 0.14 12.9 2.3 0.42 11.4 2.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2462) PseudoU_synth_1 PF01416.20 KKK17781.1 - 9.4e-11 42.1 0.0 3e-09 37.3 0.0 2.5 2 0 0 2 2 2 1 tRNA pseudouridine synthase SET PF00856.28 KKK17782.1 - 4.5e-10 40.2 0.6 1e-08 35.8 0.1 3.1 2 2 0 2 2 2 1 SET domain Ribosomal_L14 PF00238.19 KKK17783.1 - 4e-48 162.5 3.2 4.5e-48 162.4 3.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Phage_antitermQ PF06530.12 KKK17783.1 - 0.066 13.1 0.1 0.11 12.4 0.1 1.4 1 0 0 1 1 1 0 Phage antitermination protein Q Rotamase PF00639.21 KKK17784.1 - 4.1e-23 82.2 0.0 5.3e-23 81.8 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 KKK17784.1 - 5.2e-16 59.2 0.0 6.6e-16 58.9 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 KKK17784.1 - 0.0002 22.2 0.0 0.00024 21.9 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain MAM PF00629.23 KKK17784.1 - 0.01 15.7 0.0 0.012 15.5 0.0 1.1 1 0 0 1 1 1 0 MAM domain, meprin/A5/mu RNA_POL_M_15KD PF02150.16 KKK17785.1 - 3.2e-11 42.9 1.7 3.2e-11 42.9 1.7 2.7 2 1 0 2 2 2 1 RNA polymerases M/15 Kd subunit GFA PF04828.14 KKK17785.1 - 0.023 15.0 4.0 1.7 9.0 0.1 2.3 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme C1_1 PF00130.22 KKK17785.1 - 2.1 8.3 7.5 1.3 8.9 0.8 2.6 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Nudix_N_2 PF14803.6 KKK17785.1 - 3.2 7.8 8.0 5.5 7.0 1.8 3.2 3 0 0 3 3 3 0 Nudix N-terminal APH PF01636.23 KKK17786.1 - 9.3e-07 29.0 0.1 1.4e-06 28.4 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Tom37 PF10568.9 KKK17787.1 - 9.5e-39 132.6 0.6 2e-38 131.5 0.2 1.8 2 0 0 2 2 2 1 Outer mitochondrial membrane transport complex protein GST_C_6 PF17171.4 KKK17787.1 - 1.7e-10 40.5 0.0 6.9e-10 38.6 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 KKK17787.1 - 5.7e-06 27.0 0.0 5.3e-05 23.9 0.0 2.3 2 0 0 2 2 2 1 Glutathione S-transferase N-terminal domain GST_C_2 PF13410.6 KKK17787.1 - 0.001 19.1 0.1 0.006 16.6 0.0 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Hist_deacetyl PF00850.19 KKK17788.1 - 7.2e-79 265.4 0.1 9.3e-79 265.1 0.1 1.1 1 0 0 1 1 1 1 Histone deacetylase domain DUF2417 PF10329.9 KKK17820.1 - 1.6e-83 279.8 0.2 2.3e-83 279.3 0.2 1.2 1 0 0 1 1 1 1 Region of unknown function (DUF2417) Abhydrolase_1 PF00561.20 KKK17820.1 - 0.024 14.3 0.0 0.04 13.6 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KKK17821.1 - 6.8e-23 82.4 1.4 1e-22 81.8 1.4 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KKK17821.1 - 2.1e-06 27.6 0.1 8.5e-06 25.6 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KKK17821.1 - 0.0046 16.3 0.1 0.0085 15.4 0.0 1.6 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Adeno_PIX PF03955.14 KKK17821.1 - 0.11 12.7 0.0 0.24 11.6 0.0 1.5 1 0 0 1 1 1 0 Adenovirus hexon-associated protein (IX) Abhydrolase_5 PF12695.7 KKK17821.1 - 0.14 11.9 0.0 0.23 11.2 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Glyco_hydro_18 PF00704.28 KKK17822.1 - 8.5e-59 199.8 0.0 9.5e-59 199.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DUF3712 PF12505.8 KKK17823.1 - 4.2e-34 117.5 0.9 1.1e-33 116.2 0.6 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3712) Cu-oxidase_3 PF07732.15 KKK17823.1 - 0.0098 15.9 0.1 0.024 14.7 0.1 1.7 1 0 0 1 1 1 1 Multicopper oxidase FMN_red PF03358.15 KKK17824.1 - 6.1e-09 35.8 0.0 7.7e-09 35.5 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 KKK17824.1 - 5.2e-07 29.6 0.0 6.7e-07 29.2 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_1 PF00258.25 KKK17824.1 - 0.00016 21.9 0.1 0.0064 16.7 0.0 2.2 1 1 0 1 1 1 1 Flavodoxin Flavodoxin_5 PF12724.7 KKK17824.1 - 0.021 15.0 0.0 0.037 14.3 0.0 1.4 1 0 0 1 1 1 0 Flavodoxin domain zf-CCCH PF00642.24 KKK17825.1 - 1.8e-19 69.2 29.3 1.4e-06 28.0 1.1 5.2 5 0 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KKK17825.1 - 1.2e-14 53.7 28.2 0.00019 21.4 1.7 5.1 5 0 0 5 5 5 4 Zinc finger domain Torus PF16131.5 KKK17825.1 - 2.4e-12 47.5 24.1 1e-05 26.2 0.8 5.2 1 1 4 5 5 5 5 Torus domain zf-CCCH_4 PF18044.1 KKK17825.1 - 2.3e-05 24.0 0.8 2.3e-05 24.0 0.8 4.8 5 0 0 5 5 5 2 CCCH-type zinc finger zf-C3H1 PF10650.9 KKK17825.1 - 0.001 18.7 5.7 0.13 12.1 0.0 3.8 4 0 0 4 4 4 2 Putative zinc-finger domain Atrophin-1 PF03154.15 KKK17825.1 - 1.7 6.8 6.6 0.62 8.3 4.4 1.3 2 0 0 2 2 2 0 Atrophin-1 family Sel1 PF08238.12 KKK17826.1 - 7.1e-13 48.8 10.9 0.0013 19.4 4.5 4.0 4 0 0 4 4 4 3 Sel1 repeat DNA_binding_2 PF13724.6 KKK17826.1 - 5.9 7.4 8.5 2.6 8.5 2.2 3.6 2 0 0 2 2 2 0 DNA-binding domain NPL4 PF05021.15 KKK17827.1 - 4.8e-135 449.8 0.0 5.9e-135 449.5 0.0 1.1 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.15 KKK17827.1 - 1.9e-70 235.7 0.1 3.2e-70 234.9 0.1 1.4 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region DUF2080 PF09853.9 KKK17827.1 - 0.012 15.4 0.0 0.026 14.2 0.0 1.6 1 0 0 1 1 1 0 Putative transposon-encoded protein (DUF2080) UN_NPL4 PF11543.8 KKK17827.1 - 0.02 15.4 0.0 0.16 12.4 0.0 2.3 1 1 0 1 1 1 0 Nuclear pore localisation protein NPL4 DUF3752 PF12572.8 KKK17828.1 - 2.2e-45 154.9 12.3 2.2e-45 154.9 12.3 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3752) DUF4337 PF14235.6 KKK17828.1 - 0.15 12.2 2.9 0.29 11.3 2.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Sin_N PF04801.13 KKK17828.1 - 4 6.6 8.0 1.7 7.8 0.0 2.1 1 1 1 2 2 2 0 Sin-like protein conserved region SprA-related PF12118.8 KKK17828.1 - 6.6 5.8 13.6 14 4.7 13.6 1.5 1 1 0 1 1 1 0 SprA-related family Methyltransf_11 PF08241.12 KKK17829.1 - 0.00017 22.2 0.0 0.00057 20.5 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKK17829.1 - 0.087 13.5 0.0 0.18 12.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain SAP PF02037.27 KKK17830.1 - 2.4e-12 46.3 0.6 6.3e-11 41.8 0.0 2.4 2 0 0 2 2 2 1 SAP domain Tho1_MOS11_C PF18592.1 KKK17830.1 - 1.1e-10 41.1 9.4 8.4e-08 31.9 4.1 2.5 2 1 1 3 3 3 2 Tho1/MOS11 C-terminal domain WD40 PF00400.32 KKK17831.1 - 2.3e-47 158.0 24.0 5.1e-09 36.6 0.4 6.9 6 1 0 6 6 6 6 WD domain, G-beta repeat TFIID_NTD2 PF04494.15 KKK17831.1 - 2.3e-38 131.3 0.0 3.3e-38 130.8 0.0 1.2 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit, NTD2 domain ANAPC4_WD40 PF12894.7 KKK17831.1 - 2.7e-13 50.0 0.3 0.013 15.7 0.0 5.2 2 1 3 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain LisH PF08513.11 KKK17831.1 - 4.2e-07 29.7 0.0 9.6e-07 28.6 0.0 1.7 1 0 0 1 1 1 1 LisH Nup160 PF11715.8 KKK17831.1 - 0.013 14.2 5.9 0.041 12.5 0.1 3.2 3 1 0 3 3 3 0 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 KKK17831.1 - 0.15 10.8 0.0 9.4 4.8 0.0 2.7 2 1 1 3 3 3 0 Nup133 N terminal like F_actin_cap_B PF01115.17 KKK17832.1 - 4.5e-88 294.9 0.0 4.7e-75 252.3 0.0 2.2 1 1 1 2 2 2 2 F-actin capping protein, beta subunit ResIII PF04851.15 KKK17832.1 - 5e-22 78.7 0.0 9.8e-22 77.7 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KKK17832.1 - 8.5e-20 71.2 0.0 3e-19 69.4 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KKK17832.1 - 3.3e-15 56.3 0.0 7.8e-15 55.1 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 KKK17832.1 - 0.0021 17.8 0.0 0.0039 16.9 0.0 1.3 1 0 0 1 1 1 1 SWI2/SNF2 ATPase UIM PF02809.20 KKK17832.1 - 0.016 15.1 0.4 0.047 13.6 0.4 1.9 1 0 0 1 1 1 0 Ubiquitin interaction motif AAA_22 PF13401.6 KKK17832.1 - 0.026 14.8 0.0 0.069 13.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain Med11 PF10280.9 KKK17833.1 - 2.8e-43 147.7 0.2 3.5e-43 147.4 0.2 1.1 1 0 0 1 1 1 1 Mediator complex protein Med29 PF11568.8 KKK17833.1 - 0.016 15.5 0.0 0.025 14.8 0.0 1.5 1 0 0 1 1 1 0 Mediator complex subunit 29 Cep57_MT_bd PF06657.13 KKK17833.1 - 0.1 13.0 0.9 0.5 10.8 0.1 2.2 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 DUF4404 PF14357.6 KKK17833.1 - 0.46 11.2 2.6 24 5.7 0.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) MA3 PF02847.17 KKK17834.1 - 1.4e-28 99.1 0.0 3.5e-28 97.9 0.0 1.7 1 0 0 1 1 1 1 MA3 domain Hira PF07569.11 KKK17835.1 - 0.0036 17.1 0.1 22 4.7 0.0 3.3 3 0 0 3 3 3 3 TUP1-like enhancer of split DPM2 PF07297.12 KKK17836.1 - 1.5e-32 111.7 1.7 1.7e-32 111.6 1.7 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PIG-P PF08510.12 KKK17836.1 - 0.0083 16.0 0.9 0.01 15.7 0.9 1.1 1 0 0 1 1 1 1 PIG-P Phage_holin_3_6 PF07332.11 KKK17836.1 - 0.034 14.2 2.4 0.04 14.0 2.4 1.1 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III LapA_dom PF06305.11 KKK17836.1 - 0.048 13.5 0.1 0.048 13.5 0.1 1.7 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain DUF4229 PF14012.6 KKK17836.1 - 0.052 13.6 1.3 0.12 12.5 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4229) Macoilin PF09726.9 KKK17837.1 - 4.5 5.7 7.4 4.3 5.8 7.4 1.1 1 0 0 1 1 1 0 Macoilin family HD PF01966.22 KKK17838.1 - 1.9e-06 28.1 1.1 6.3e-06 26.4 0.2 2.0 2 0 0 2 2 2 1 HD domain AAA PF00004.29 KKK17839.1 - 1e-47 161.8 0.0 2.2e-42 144.6 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KKK17839.1 - 5.8e-10 38.8 0.0 2.1e-09 37.0 0.0 1.9 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 KKK17839.1 - 4.3e-07 30.5 0.2 4e-05 24.1 0.0 3.5 2 1 0 2 2 2 1 AAA ATPase domain IstB_IS21 PF01695.17 KKK17839.1 - 5.4e-07 29.5 0.0 3.3e-06 27.0 0.0 2.1 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_2 PF07724.14 KKK17839.1 - 5.4e-06 26.6 0.0 1.2e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 KKK17839.1 - 0.00026 21.0 0.1 0.0013 18.8 0.0 2.2 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KKK17839.1 - 0.00074 19.8 0.6 0.023 14.9 0.1 3.4 3 1 0 3 3 2 1 AAA domain Bromodomain PF00439.25 KKK17839.1 - 0.0015 18.5 0.0 0.0041 17.1 0.0 1.7 1 0 0 1 1 1 1 Bromodomain RNA_helicase PF00910.22 KKK17839.1 - 0.0044 17.4 0.0 0.011 16.1 0.0 1.7 1 0 0 1 1 1 1 RNA helicase AAA_30 PF13604.6 KKK17839.1 - 0.0087 15.8 0.0 0.019 14.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain Sigma54_activ_2 PF14532.6 KKK17839.1 - 0.0088 16.2 0.0 0.95 9.6 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_25 PF13481.6 KKK17839.1 - 0.012 15.2 0.0 0.045 13.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 KKK17839.1 - 0.013 15.6 0.0 0.037 14.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KKK17839.1 - 0.017 15.3 0.0 0.046 13.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KKK17839.1 - 0.017 15.7 0.0 0.074 13.6 0.0 2.2 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.13 KKK17839.1 - 0.019 14.2 0.0 0.033 13.4 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain RuvB_N PF05496.12 KKK17839.1 - 0.031 14.0 0.0 0.078 12.7 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 KKK17839.1 - 0.044 13.2 0.0 0.11 11.8 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI TsaE PF02367.17 KKK17839.1 - 0.045 13.8 0.0 1.8 8.6 0.0 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 KKK17839.1 - 0.052 14.1 0.0 0.2 12.1 0.0 2.0 2 0 0 2 2 1 0 ABC transporter Sigma54_activat PF00158.26 KKK17839.1 - 0.064 13.0 0.0 1.4 8.6 0.0 2.7 2 1 0 2 2 2 0 Sigma-54 interaction domain AAA_28 PF13521.6 KKK17839.1 - 0.084 13.1 0.0 0.19 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KKK17839.1 - 0.11 12.5 0.0 0.34 10.8 0.0 1.9 2 0 0 2 2 2 0 NACHT domain Parvo_NS1 PF01057.17 KKK17839.1 - 0.11 11.6 0.0 0.22 10.5 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DUF2075 PF09848.9 KKK17839.1 - 0.13 11.5 0.0 0.24 10.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_7 PF12775.7 KKK17839.1 - 0.14 11.7 0.0 0.27 10.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_3 PF07726.11 KKK17839.1 - 0.15 11.9 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Torsin PF06309.11 KKK17839.1 - 0.21 11.7 0.0 0.62 10.2 0.0 1.7 1 0 0 1 1 1 0 Torsin AAA_11 PF13086.6 KKK17839.1 - 0.36 10.6 0.0 0.36 10.6 0.0 3.6 3 1 0 3 3 1 0 AAA domain Sec66 PF09802.9 KKK17840.1 - 1.3e-82 275.7 1.9 1.6e-82 275.5 1.9 1.1 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 DUF874 PF05917.11 KKK17840.1 - 0.015 14.3 3.0 0.021 13.9 3.0 1.1 1 0 0 1 1 1 0 Helicobacter pylori protein of unknown function (DUF874) DUF3848 PF12959.7 KKK17840.1 - 0.019 15.0 0.0 0.042 13.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3848) Sec2p PF06428.11 KKK17840.1 - 0.043 13.8 2.3 0.11 12.5 2.3 1.7 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p Rib_recp_KP_reg PF05104.12 KKK17840.1 - 0.15 13.1 18.8 0.081 14.0 15.1 2.0 2 0 0 2 2 2 0 Ribosome receptor lysine/proline rich region Glyoxalase PF00903.25 KKK17842.1 - 2.1e-10 40.9 0.0 1.1e-09 38.5 0.0 2.1 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 KKK17842.1 - 0.00064 20.0 0.0 0.0011 19.2 0.0 1.5 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 KKK17842.1 - 0.1 13.4 0.0 0.71 10.7 0.0 2.3 2 1 0 2 2 2 0 Glyoxalase-like domain BCDHK_Adom3 PF10436.9 KKK17843.1 - 1.1e-45 155.4 0.0 1.5e-45 154.9 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 KKK17843.1 - 4.3e-12 46.5 0.0 1.3e-11 45.0 0.0 1.8 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim_4 PF13662.6 KKK17843.1 - 0.008 16.6 0.1 9.5 6.8 0.0 3.2 3 0 0 3 3 3 1 Toprim domain HATPase_c_3 PF13589.6 KKK17843.1 - 0.14 12.0 0.0 0.88 9.4 0.0 2.1 1 1 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase RIBIOP_C PF04950.12 KKK17844.1 - 1.3e-96 323.5 0.0 1.3e-96 323.5 0.0 1.5 2 0 0 2 2 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 KKK17844.1 - 2.6e-28 97.9 0.0 6.6e-28 96.6 0.0 1.8 1 0 0 1 1 1 1 AARP2CN (NUC121) domain AAA_22 PF13401.6 KKK17844.1 - 1.5e-05 25.2 0.2 4.8e-05 23.7 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.6 KKK17844.1 - 7.7e-05 23.1 0.0 0.00021 21.7 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain GTP_EFTU PF00009.27 KKK17844.1 - 0.00015 21.4 0.0 0.016 14.7 0.0 2.5 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_33 PF13671.6 KKK17844.1 - 0.00027 21.1 1.5 0.00038 20.6 0.0 2.1 2 0 0 2 2 1 1 AAA domain AAA PF00004.29 KKK17844.1 - 0.00074 20.0 0.0 0.0017 18.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 KKK17844.1 - 0.0022 18.1 0.1 0.0068 16.5 0.1 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.27 KKK17844.1 - 0.0054 17.2 1.1 0.017 15.6 0.0 2.4 3 0 0 3 3 1 1 ABC transporter AAA_19 PF13245.6 KKK17844.1 - 0.0059 16.9 0.0 0.013 15.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 KKK17844.1 - 0.0076 15.5 0.0 0.015 14.5 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain NACHT PF05729.12 KKK17844.1 - 0.0097 15.8 0.0 0.019 14.9 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_5 PF07728.14 KKK17844.1 - 0.016 15.2 0.2 0.14 12.2 0.1 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 KKK17844.1 - 0.017 14.6 0.0 0.041 13.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 KKK17844.1 - 0.019 15.3 0.0 0.046 14.1 0.0 1.6 1 0 0 1 1 1 0 RNA helicase cobW PF02492.19 KKK17844.1 - 0.022 14.4 0.2 0.039 13.5 0.2 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 KKK17844.1 - 0.025 14.3 0.0 0.052 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 KKK17844.1 - 0.038 13.7 0.0 0.37 10.5 0.0 2.1 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation NTPase_1 PF03266.15 KKK17844.1 - 0.038 13.9 0.3 0.072 13.0 0.3 1.4 1 0 0 1 1 1 0 NTPase RsgA_GTPase PF03193.16 KKK17844.1 - 0.039 13.9 0.0 0.13 12.2 0.0 1.8 2 0 0 2 2 2 0 RsgA GTPase MobB PF03205.14 KKK17844.1 - 0.048 13.6 0.1 0.3 11.0 0.1 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.6 KKK17844.1 - 0.056 14.0 0.1 0.056 14.0 0.1 2.8 3 0 0 3 3 2 0 AAA domain AAA_14 PF13173.6 KKK17844.1 - 0.059 13.4 0.0 0.19 11.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain Septin PF00735.18 KKK17844.1 - 0.078 12.2 1.1 0.32 10.2 0.0 2.1 2 0 0 2 2 2 0 Septin KAP_NTPase PF07693.14 KKK17844.1 - 0.082 12.1 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 KAP family P-loop domain ATPase_2 PF01637.18 KKK17844.1 - 0.085 12.8 0.0 0.085 12.8 0.0 1.9 2 0 0 2 2 1 0 ATPase domain predominantly from Archaea Roc PF08477.13 KKK17844.1 - 0.12 12.6 0.0 0.27 11.5 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 KKK17844.1 - 0.18 11.6 0.0 0.34 10.7 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_11 PF13086.6 KKK17844.1 - 0.29 10.9 0.1 0.29 10.9 0.1 3.2 3 0 0 3 3 3 0 AAA domain Aminotran_1_2 PF00155.21 KKK17845.1 - 1.2e-22 80.7 0.0 1.5e-22 80.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 KKK17845.1 - 0.056 12.2 0.0 0.2 10.4 0.0 1.8 1 1 0 1 1 1 0 Alanine-glyoxylate amino-transferase Beta_elim_lyase PF01212.21 KKK17845.1 - 0.087 12.1 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 KKK17845.1 - 0.15 11.4 0.0 1.7 7.9 0.0 2.0 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family Tfb4 PF03850.14 KKK17846.1 - 8.1e-117 389.6 0.0 9.4e-117 389.4 0.0 1.0 1 0 0 1 1 1 1 Transcription factor Tfb4 PRIMA1 PF16101.5 KKK17846.1 - 0.0065 16.5 0.9 0.016 15.2 0.9 1.6 1 0 0 1 1 1 1 Proline-rich membrane anchor 1 CAP_N PF01213.19 KKK17846.1 - 0.1 12.1 1.1 0.15 11.5 1.1 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal GDPD PF03009.17 KKK17847.1 - 2e-68 231.0 0.0 1.4e-67 228.2 0.0 2.3 3 0 0 3 3 3 1 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.7 KKK17847.1 - 4.4e-24 84.9 0.0 6.5e-09 36.3 0.1 3.8 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KKK17847.1 - 2.8e-22 78.8 2.7 2.8e-08 34.1 0.0 5.2 6 0 0 6 6 6 3 Ankyrin repeats (many copies) SPX PF03105.19 KKK17847.1 - 5e-22 79.3 14.3 3.3e-10 40.5 0.0 4.3 4 1 1 5 5 5 3 SPX domain Ank_5 PF13857.6 KKK17847.1 - 3.3e-18 65.5 1.0 8e-08 32.4 0.1 4.2 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KKK17847.1 - 2.3e-15 55.1 0.3 0.0067 16.8 0.0 6.4 5 0 0 5 5 5 3 Ankyrin repeat Ank PF00023.30 KKK17847.1 - 5.4e-15 55.1 0.8 0.0027 18.1 0.0 6.6 7 0 0 7 7 7 4 Ankyrin repeat Actin PF00022.19 KKK17848.1 - 1.2e-87 294.2 0.0 4e-85 285.9 0.0 2.0 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 KKK17848.1 - 0.051 12.4 0.0 1.1 8.0 0.0 2.2 2 0 0 2 2 2 0 MreB/Mbl protein Asparaginase_2 PF01112.18 KKK17849.1 - 1.1e-49 169.1 0.9 2.1e-31 109.1 0.0 2.2 2 0 0 2 2 2 2 Asparaginase IstB_IS21 PF01695.17 KKK17849.1 - 0.015 15.0 0.0 0.028 14.1 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Vps55 PF04133.14 KKK17852.1 - 1.9e-42 143.9 6.6 2.2e-42 143.7 6.6 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 Proteasome PF00227.26 KKK17853.1 - 4.1e-49 166.7 0.1 5.3e-49 166.3 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KKK17853.1 - 1.3e-12 47.2 0.4 2e-12 46.5 0.4 1.3 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature UPF0220 PF05255.11 KKK17854.1 - 1.1e-48 164.9 1.4 1.3e-48 164.7 1.4 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) Lysine_decarbox PF03641.14 KKK17855.1 - 2.9e-25 88.9 0.0 6.7e-25 87.7 0.0 1.6 1 1 0 1 1 1 1 Possible lysine decarboxylase LDcluster4 PF18306.1 KKK17855.1 - 0.012 15.2 0.4 0.16 11.5 0.0 2.3 2 0 0 2 2 2 0 SLOG cluster4 family DAGK_cat PF00781.24 KKK17855.1 - 0.68 9.6 3.0 13 5.4 0.1 3.1 2 1 1 3 3 3 0 Diacylglycerol kinase catalytic domain DUF3684 PF12449.8 KKK17856.1 - 0 1392.1 0.0 0 1391.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3684) Chorismate_bind PF00425.18 KKK17856.1 - 1.2e-64 218.4 0.0 1.4e-63 214.9 0.0 2.2 1 1 0 1 1 1 1 chorismate binding enzyme Med6 PF04934.14 KKK17856.1 - 2.2e-36 124.6 0.0 5.2e-36 123.4 0.0 1.7 1 0 0 1 1 1 1 MED6 mediator sub complex component GATase PF00117.28 KKK17856.1 - 3.9e-26 92.0 0.0 1.7e-25 89.9 0.0 1.9 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.13 KKK17856.1 - 9.9e-08 32.3 0.0 3.1e-07 30.7 0.0 1.9 1 0 0 1 1 1 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.13 KKK17856.1 - 0.00068 19.4 0.3 0.0028 17.4 0.1 2.1 2 0 0 2 2 2 1 Peptidase C26 HATPase_c_3 PF13589.6 KKK17856.1 - 0.0034 17.2 0.0 0.01 15.7 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase UPF0767 PF15990.5 KKK17856.1 - 0.16 12.1 1.3 0.46 10.7 1.3 1.7 1 0 0 1 1 1 0 UPF0767 family Sld7_C PF18596.1 KKK17857.1 - 8e-14 51.5 0.0 2.3e-13 50.0 0.0 1.8 2 0 0 2 2 2 1 Sld7 C-terminal domain WW PF00397.26 KKK17861.1 - 2.1e-08 34.1 3.1 2.1e-08 34.1 3.1 2.1 2 0 0 2 2 2 1 WW domain DNA_pol_phi PF04931.13 KKK17861.1 - 1.3 7.1 17.9 2.2 6.3 17.9 1.3 1 0 0 1 1 1 0 DNA polymerase phi Mcp5_PH PF12814.7 KKK17866.1 - 7.5e-46 155.2 0.4 1.5e-45 154.3 0.4 1.5 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology PH PF00169.29 KKK17866.1 - 8.2e-07 29.5 0.1 2e-06 28.2 0.1 1.7 1 0 0 1 1 1 1 PH domain Flagellin_C PF00700.21 KKK17866.1 - 0.081 13.3 0.1 0.32 11.4 0.1 2.1 1 0 0 1 1 1 0 Bacterial flagellin C-terminal helical region MukF_C PF17193.4 KKK17866.1 - 1.4 9.1 4.9 0.44 10.7 1.4 1.9 2 1 0 2 2 2 0 MukF C-terminal domain BAR PF03114.18 KKK17867.1 - 6.7e-08 32.5 2.9 9.5e-08 32.0 2.8 1.3 1 1 0 1 1 1 1 BAR domain DUF4541 PF15074.6 KKK17867.1 - 0.074 13.7 3.6 0.19 12.3 3.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4541) DUF2439 PF10382.9 KKK17868.1 - 1.5e-28 98.9 0.3 2.4e-28 98.2 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) Utp14 PF04615.13 KKK17881.1 - 1.8 7.1 23.8 2.1 6.8 23.8 1.1 1 0 0 1 1 1 0 Utp14 protein GREB1 PF15782.5 KKK17881.1 - 5.7 3.9 31.4 6.9 3.6 31.4 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer NPP1 PF05630.11 KKK17891.1 - 2.8e-54 184.2 0.0 3.5e-54 183.9 0.0 1.0 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) SmpA_OmlA PF04355.13 KKK17892.1 - 0.042 13.6 0.0 0.066 13.0 0.0 1.3 1 0 0 1 1 1 0 SmpA / OmlA family p450 PF00067.22 KKK17893.1 - 6.2e-42 143.9 0.0 1.2e-41 143.0 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 Transp_cyt_pur PF02133.15 KKK17894.1 - 1.2e-27 96.8 31.2 1.6e-27 96.4 31.2 1.2 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF2826 PF11442.8 KKK17894.1 - 0.04 13.8 0.1 0.1 12.4 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2826) Methyltransf_11 PF08241.12 KKK17897.1 - 5.7e-08 33.3 0.0 1.3e-07 32.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKK17897.1 - 0.0047 17.6 0.0 0.012 16.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KKK17897.1 - 0.018 14.8 0.0 0.057 13.2 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain SH3BGR PF04908.15 KKK17899.1 - 0.0031 17.6 0.0 0.013 15.7 0.0 2.1 2 0 0 2 2 2 1 SH3-binding, glutamic acid-rich protein Ndc1_Nup PF09531.10 KKK17899.1 - 3.6 6.1 9.6 4.4 5.9 9.6 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Pneumo_att_G PF05539.11 KKK17899.1 - 9.5 5.7 10.3 13 5.2 10.3 1.2 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G Ribul_P_3_epim PF00834.19 KKK17900.1 - 1.1e-61 207.7 0.0 1.3e-60 204.2 0.0 2.0 1 1 0 1 1 1 1 Ribulose-phosphate 3 epimerase family ThiG PF05690.14 KKK17900.1 - 0.015 14.6 0.2 0.023 14.0 0.2 1.2 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG Amidohydro_2 PF04909.14 KKK17900.1 - 0.026 14.3 0.5 0.17 11.7 0.2 2.2 1 1 1 2 2 2 0 Amidohydrolase QRPTase_C PF01729.19 KKK17900.1 - 0.027 14.2 0.2 1.4 8.7 0.0 2.2 2 0 0 2 2 2 0 Quinolinate phosphoribosyl transferase, C-terminal domain OMPdecase PF00215.24 KKK17900.1 - 0.079 12.5 0.0 0.11 12.0 0.0 1.5 1 1 0 1 1 1 0 Orotidine 5'-phosphate decarboxylase / HUMPS family LSM PF01423.22 KKK17902.1 - 1.1e-16 60.2 0.9 1.5e-16 59.8 0.9 1.2 1 0 0 1 1 1 1 LSM domain LRR_9 PF14580.6 KKK17902.1 - 0.011 15.2 0.2 0.014 14.9 0.2 1.2 1 0 0 1 1 1 0 Leucine-rich repeat Hfq PF17209.3 KKK17902.1 - 0.056 13.1 0.1 0.093 12.4 0.1 1.3 1 0 0 1 1 1 0 Hfq protein Cellulase PF00150.18 KKK17903.1 - 2.1e-17 63.5 0.4 4.4e-17 62.4 0.4 1.5 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) TFIIS_C PF01096.18 KKK17905.1 - 1.8 8.5 5.5 0.17 11.8 0.5 1.8 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) PHO4 PF01384.20 KKK17906.1 - 4.6e-103 344.8 19.2 5.3e-103 344.6 19.2 1.0 1 0 0 1 1 1 1 Phosphate transporter family UPF0444 PF15475.6 KKK17906.1 - 0.77 10.1 7.9 1.3 9.3 0.7 2.8 2 0 0 2 2 2 0 Transmembrane protein C12orf23, UPF0444 MFS_1 PF07690.16 KKK17907.1 - 1.7e-23 83.2 29.1 1.7e-23 83.2 29.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Cu-oxidase_3 PF07732.15 KKK17908.1 - 5.3e-39 132.9 4.4 7e-39 132.5 0.6 2.9 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.22 KKK17908.1 - 1.6e-32 112.8 0.0 1.4e-31 109.8 0.0 2.1 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 KKK17908.1 - 5.3e-15 55.4 9.6 4.3e-14 52.4 0.4 2.9 2 1 0 2 2 2 2 Multicopper oxidase DUF1100 PF06500.11 KKK17909.1 - 7.8e-11 41.4 0.0 1.1e-10 41.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Peptidase_S9 PF00326.21 KKK17909.1 - 3.6e-06 26.6 0.0 8.2e-06 25.4 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 KKK17909.1 - 9.2e-05 22.2 0.0 0.00015 21.5 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_1 PF00561.20 KKK17909.1 - 0.00018 21.2 0.1 0.0005 19.8 0.1 1.6 1 1 1 2 2 2 1 alpha/beta hydrolase fold BAAT_C PF08840.11 KKK17909.1 - 0.0029 17.6 0.0 0.014 15.4 0.0 1.9 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Hydrolase_4 PF12146.8 KKK17909.1 - 0.0092 15.3 0.1 0.017 14.4 0.1 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DLH PF01738.18 KKK17909.1 - 0.034 13.7 0.0 0.28 10.7 0.0 2.1 1 1 0 1 1 1 0 Dienelactone hydrolase family Esterase PF00756.20 KKK17909.1 - 0.056 13.1 0.0 0.15 11.6 0.0 1.7 2 0 0 2 2 2 0 Putative esterase Esterase_phd PF10503.9 KKK17909.1 - 0.12 11.8 0.1 0.21 11.1 0.1 1.3 1 0 0 1 1 1 0 Esterase PHB depolymerase Glyco_hydro_75 PF07335.11 KKK17910.1 - 3e-64 216.2 0.5 4e-64 215.8 0.5 1.2 1 0 0 1 1 1 1 Fungal chitosanase of glycosyl hydrolase group 75 UDPG_MGDP_dh_N PF03721.14 KKK17911.1 - 3.6e-36 124.5 0.1 3e-23 82.4 0.0 2.2 1 1 1 2 2 2 2 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh_C PF03720.15 KKK17911.1 - 7.7e-12 45.6 0.0 3.2e-11 43.6 0.0 2.0 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh PF00984.19 KKK17911.1 - 2.5e-10 40.4 0.0 3.9e-09 36.6 0.0 2.7 2 1 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain Ldh_1_N PF00056.23 KKK17911.1 - 0.18 11.9 0.1 25 5.0 0.0 3.2 3 0 0 3 3 3 0 lactate/malate dehydrogenase, NAD binding domain AA_permease PF00324.21 KKK17912.1 - 5.8e-114 381.3 39.5 7.1e-114 381.0 39.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KKK17912.1 - 3.7e-35 121.6 45.2 4.5e-35 121.3 45.2 1.0 1 0 0 1 1 1 1 Amino acid permease CBM-like PF14683.6 KKK17913.1 - 2.8e-38 131.4 0.0 6.6e-38 130.2 0.0 1.7 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.6 KKK17913.1 - 3.1e-14 52.5 0.6 1.2e-13 50.6 0.4 2.2 2 0 0 2 2 2 1 Polysaccharide lyase family 4, domain II CarboxypepD_reg PF13620.6 KKK17913.1 - 4.4e-09 36.5 5.0 1.2e-08 35.1 1.1 3.0 3 1 0 3 3 3 1 Carboxypeptidase regulatory-like domain SdrD_B PF17210.3 KKK17913.1 - 0.015 15.5 1.9 0.41 10.9 0.2 3.0 3 0 0 3 3 3 0 SdrD B-like domain CarbopepD_reg_2 PF13715.6 KKK17913.1 - 0.017 15.1 0.1 0.23 11.5 0.1 2.8 2 1 0 2 2 2 0 CarboxypepD_reg-like domain RhgB_N PF09284.10 KKK17913.1 - 0.036 13.6 0.0 0.061 12.9 0.0 1.3 1 0 0 1 1 1 0 Rhamnogalacturonan lyase B, N-terminal DUF4198 PF10670.9 KKK17913.1 - 0.055 13.8 0.1 0.28 11.5 0.0 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4198) Ald_Xan_dh_C2 PF02738.18 KKK17914.1 - 4e-203 675.8 0.6 5.5e-203 675.4 0.6 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.21 KKK17914.1 - 1.3e-40 138.9 0.0 2.5e-40 138.0 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase CO_deh_flav_C PF03450.17 KKK17914.1 - 1.9e-32 111.5 0.1 1.2e-31 108.9 0.0 2.4 2 0 0 2 2 2 1 CO dehydrogenase flavoprotein C-terminal domain Ald_Xan_dh_C PF01315.22 KKK17914.1 - 1.1e-28 99.8 0.0 2.5e-28 98.6 0.0 1.6 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2_2 PF01799.20 KKK17914.1 - 3.4e-25 87.9 0.0 8.4e-25 86.6 0.0 1.7 1 0 0 1 1 1 1 [2Fe-2S] binding domain Fer2 PF00111.27 KKK17914.1 - 5.1e-08 32.8 0.0 3e-07 30.3 0.0 2.4 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain AAA PF00004.29 KKK17915.1 - 1.9e-16 60.7 0.0 4.4e-06 27.2 0.0 3.4 3 0 0 3 3 3 3 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KKK17915.1 - 1.9e-11 44.4 0.7 0.01 16.1 0.0 4.5 3 2 1 4 4 4 3 AAA domain AAA_33 PF13671.6 KKK17915.1 - 9.3e-09 35.6 0.4 0.0027 17.9 0.0 4.4 3 3 0 3 3 3 2 AAA domain AAA_18 PF13238.6 KKK17915.1 - 2.6e-07 31.2 0.0 1.3 9.6 0.0 3.7 3 0 0 3 3 3 3 AAA domain AAA_5 PF07728.14 KKK17915.1 - 4.7e-07 29.9 0.1 0.43 10.6 0.0 3.8 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) Torsin PF06309.11 KKK17915.1 - 8.3e-07 29.2 0.0 0.054 13.6 0.0 3.6 3 0 0 3 3 3 1 Torsin AAA_16 PF13191.6 KKK17915.1 - 1.9e-06 28.4 0.3 0.76 10.1 0.0 4.0 3 1 0 3 3 3 2 AAA ATPase domain Mg_chelatase PF01078.21 KKK17915.1 - 1.2e-05 24.8 0.0 0.29 10.5 0.0 3.2 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 KKK17915.1 - 1.6e-05 24.7 0.0 0.5 10.1 0.0 3.5 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_30 PF13604.6 KKK17915.1 - 0.00016 21.4 0.3 0.34 10.6 0.0 3.7 3 1 0 3 3 3 1 AAA domain AAA_24 PF13479.6 KKK17915.1 - 0.00017 21.4 0.0 0.2 11.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 KKK17915.1 - 0.00043 20.6 0.1 2.2 8.7 0.0 3.9 5 1 0 5 5 3 1 RNA helicase AAA_2 PF07724.14 KKK17915.1 - 0.0014 18.8 0.0 1.3 9.2 0.0 3.9 3 1 0 3 3 3 1 AAA domain (Cdc48 subfamily) TsaE PF02367.17 KKK17915.1 - 0.0015 18.5 0.0 1.7 8.6 0.0 3.3 3 0 0 3 3 3 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_19 PF13245.6 KKK17915.1 - 0.0018 18.6 0.1 2.3 8.5 0.0 3.8 3 1 0 3 3 3 1 AAA domain IstB_IS21 PF01695.17 KKK17915.1 - 0.0028 17.4 0.0 8.9 6.0 0.0 3.4 3 0 0 3 3 3 0 IstB-like ATP binding protein ABC_tran PF00005.27 KKK17915.1 - 0.0045 17.5 0.0 1.1 9.7 0.0 3.3 3 1 0 3 3 3 1 ABC transporter AAA_28 PF13521.6 KKK17915.1 - 0.0046 17.2 7.2 4.4 7.5 0.0 4.6 5 0 0 5 5 5 1 AAA domain Sigma54_activat PF00158.26 KKK17915.1 - 0.0099 15.6 0.0 11 5.7 0.0 3.3 3 0 0 3 3 3 0 Sigma-54 interaction domain NACHT PF05729.12 KKK17915.1 - 0.011 15.6 0.1 2.7 7.9 0.0 3.1 3 0 0 3 3 2 0 NACHT domain DNA_pol3_delta2 PF13177.6 KKK17915.1 - 0.016 15.0 0.0 22 4.8 0.0 3.4 3 1 1 4 4 3 0 DNA polymerase III, delta subunit AAA_29 PF13555.6 KKK17915.1 - 0.021 14.6 0.0 7.3 6.4 0.0 3.1 3 0 0 3 3 3 0 P-loop containing region of AAA domain NAD_binding_9 PF13454.6 KKK17915.1 - 0.041 13.9 0.0 0.099 12.6 0.0 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding NB-ARC PF00931.22 KKK17915.1 - 0.043 13.0 0.0 11 5.1 0.0 3.6 4 0 0 4 4 4 0 NB-ARC domain TniB PF05621.11 KKK17915.1 - 0.081 12.3 0.0 8 5.8 0.0 3.2 3 0 0 3 3 3 0 Bacterial TniB protein PRK PF00485.18 KKK17915.1 - 0.089 12.5 2.0 3.9 7.2 0.1 3.6 4 0 0 4 4 4 0 Phosphoribulokinase / Uridine kinase family DUF3391 PF11871.8 KKK17915.1 - 0.094 13.2 0.0 0.22 12.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) AAA_7 PF12775.7 KKK17915.1 - 0.11 11.9 0.0 9.1 5.8 0.0 2.8 3 0 0 3 3 3 0 P-loop containing dynein motor region Rad17 PF03215.15 KKK17915.1 - 0.13 12.2 0.0 7 6.5 0.0 2.7 3 0 0 3 3 2 0 Rad17 P-loop domain NTPase_1 PF03266.15 KKK17915.1 - 0.13 12.2 0.1 16 5.3 0.0 2.6 2 0 0 2 2 2 0 NTPase Cytidylate_kin PF02224.18 KKK17915.1 - 0.13 12.0 0.6 6.2 6.5 0.0 3.5 4 0 0 4 4 4 0 Cytidylate kinase APS_kinase PF01583.20 KKK17915.1 - 0.16 11.9 0.1 13 5.7 0.0 2.7 3 0 0 3 3 3 0 Adenylylsulphate kinase AAA_lid_6 PF17866.1 KKK17915.1 - 3 8.1 6.2 1.2 9.4 1.1 3.0 3 0 0 3 3 3 0 AAA lid domain MIT PF04212.18 KKK17916.1 - 5.9e-05 23.1 0.3 0.0001 22.3 0.3 1.4 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain Baculo_LEF-11 PF06385.12 KKK17916.1 - 0.016 15.7 0.1 0.03 14.8 0.1 1.4 1 0 0 1 1 1 0 Baculovirus LEF-11 protein TPR_1 PF00515.28 KKK17916.1 - 0.14 12.1 0.1 0.26 11.2 0.1 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat ADH_zinc_N PF00107.26 KKK17918.1 - 7.2e-17 61.6 0.3 1.4e-16 60.7 0.3 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KKK17918.1 - 1.6e-05 24.8 0.0 3.2e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KKK17918.1 - 1.7e-05 25.9 0.0 3.9e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 KKK17918.1 - 0.018 14.5 0.1 0.1 12.0 0.1 2.2 2 0 0 2 2 2 0 short chain dehydrogenase FERM_C PF09380.10 KKK17918.1 - 0.095 13.1 0.0 0.18 12.2 0.0 1.4 1 0 0 1 1 1 0 FERM C-terminal PH-like domain PI3K_P85_iSH2 PF16454.5 KKK17918.1 - 0.14 11.8 0.1 0.31 10.6 0.1 1.5 1 0 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Aminotran_5 PF00266.19 KKK17919.1 - 6.8e-15 54.9 0.0 9.6e-15 54.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 KKK17919.1 - 4.3e-08 32.7 0.0 6.1e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 KKK17919.1 - 0.047 13.0 0.0 0.53 9.5 0.0 2.0 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family GYF PF02213.16 KKK17920.1 - 1.5e-18 66.2 0.3 3.2e-18 65.1 0.3 1.6 1 0 0 1 1 1 1 GYF domain ALS2CR11 PF15729.5 KKK17920.1 - 4.2 6.4 7.5 6.9 5.7 7.5 1.3 1 0 0 1 1 1 0 Amyotrophic lateral sclerosis 2 candidate 11 CPBP PF02517.16 KKK17922.1 - 2.2e-16 60.0 6.2 2.2e-16 60.0 6.2 2.5 3 1 0 3 3 3 1 CPBP intramembrane metalloprotease tRNA-synt_1 PF00133.22 KKK17923.1 - 8.2e-47 159.7 0.5 5.1e-38 130.7 0.0 4.9 1 1 1 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.6 KKK17923.1 - 3.4e-41 140.8 0.0 4.9e-41 140.3 0.0 1.2 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 Suc_Fer-like PF06999.12 KKK17923.1 - 2.9e-39 135.0 0.0 5.1e-39 134.2 0.0 1.3 1 0 0 1 1 1 1 Sucrase/ferredoxin-like tRNA-synt_1g PF09334.11 KKK17923.1 - 2e-26 92.7 0.1 1.8e-22 79.6 0.0 3.1 2 1 1 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1d PF00750.19 KKK17923.1 - 0.023 13.7 0.0 0.036 13.0 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (R) Anticodon_1 PF08264.13 KKK17924.1 - 2.2e-10 40.7 0.0 4.3e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1 PF00133.22 KKK17924.1 - 4.3e-06 25.3 0.0 1.1e-05 24.0 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 KKK17924.1 - 0.12 11.1 0.0 0.2 10.3 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (M) 2-Hacid_dh_C PF02826.19 KKK17925.1 - 4.1e-50 169.6 0.0 8.3e-50 168.6 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KKK17925.1 - 7.6e-15 54.8 0.0 1e-14 54.3 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KKK17925.1 - 0.00019 21.6 0.0 0.00043 20.5 0.0 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 KKK17925.1 - 0.14 12.3 0.0 0.34 11.0 0.0 1.7 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase PROCN PF08083.11 KKK17925.1 - 0.18 10.5 0.0 0.25 10.0 0.0 1.1 1 0 0 1 1 1 0 PROCN (NUC071) domain BNR_4 PF15892.5 KKK17926.1 - 0.084 12.2 0.0 0.093 12.1 0.0 1.1 1 0 0 1 1 1 0 BNR repeat-containing family member Autoind_bind PF03472.15 KKK17926.1 - 0.092 12.2 0.9 7.1 6.1 0.1 2.1 2 0 0 2 2 2 0 Autoinducer binding domain Drf_GBD PF06371.13 KKK17927.1 - 9.9e-72 240.4 0.4 2.4e-71 239.2 0.0 1.8 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 KKK17927.1 - 2.4e-54 183.9 0.2 1.6e-52 178.0 0.0 2.6 1 1 1 2 2 2 2 Diaphanous FH3 Domain Mis12 PF05859.12 KKK17927.1 - 0.3 11.2 3.4 0.78 9.8 3.4 1.7 1 0 0 1 1 1 0 Mis12 protein GTA_holin_3TM PF11351.8 KKK17927.1 - 0.37 11.3 3.0 1.3 9.6 3.0 2.0 1 0 0 1 1 1 0 Holin of 3TMs, for gene-transfer release MBOAT PF03062.19 KKK17928.1 - 1.4e-46 159.5 7.2 4.1e-46 157.9 7.2 1.8 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family DUF679 PF05078.12 KKK17928.1 - 0.044 13.7 0.1 0.082 12.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF679) DUF983 PF06170.12 KKK17928.1 - 0.11 12.9 0.3 0.32 11.4 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF983) Sec1 PF00995.23 KKK17929.1 - 5.8e-133 445.1 0.1 6.8e-133 444.9 0.1 1.0 1 0 0 1 1 1 1 Sec1 family B12-binding PF02310.19 KKK17929.1 - 0.015 15.3 0.1 0.043 13.9 0.1 1.7 1 0 0 1 1 1 0 B12 binding domain Nop14 PF04147.12 KKK17930.1 - 6.5e-288 957.7 30.4 8e-288 957.4 30.4 1.1 1 0 0 1 1 1 1 Nop14-like family NADH-u_ox-rdase PF10785.9 KKK17930.1 - 0.12 13.0 0.0 0.26 12.0 0.0 1.5 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit Noc2 PF03715.13 KKK17930.1 - 0.19 10.9 0.0 0.41 9.9 0.0 1.5 1 0 0 1 1 1 0 Noc2p family PPR_2 PF13041.6 KKK17931.1 - 9.6e-07 28.9 1.0 1.8 8.8 0.0 5.5 7 0 0 7 7 7 2 PPR repeat family AAA_lid_7 PF17867.1 KKK17931.1 - 0.048 13.9 1.1 3.3 8.0 0.0 3.4 3 0 0 3 3 3 0 Midasin AAA lid domain PPR PF01535.20 KKK17931.1 - 0.074 13.3 2.0 11 6.5 0.0 4.3 5 0 0 5 5 5 0 PPR repeat RhoGAP PF00620.27 KKK17931.1 - 0.19 11.5 0.7 9.7 6.0 0.2 2.5 2 0 0 2 2 2 0 RhoGAP domain CLZ PF16526.5 KKK17931.1 - 9 6.7 7.9 12 6.3 0.9 3.6 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels HEAT_2 PF13646.6 KKK17932.1 - 0.0025 18.2 0.1 0.0062 16.9 0.1 1.7 1 0 0 1 1 1 1 HEAT repeats Myc_N PF01056.18 KKK17932.1 - 0.034 14.0 0.0 0.043 13.7 0.0 1.2 1 0 0 1 1 1 0 Myc amino-terminal region HEAT PF02985.22 KKK17932.1 - 0.094 13.0 0.0 3 8.3 0.0 2.9 2 0 0 2 2 2 0 HEAT repeat ORC_WH_C PF18137.1 KKK17933.1 - 1.8e-25 89.6 0.7 6.8e-16 58.6 0.1 2.4 1 1 1 2 2 2 2 Origin recognition complex winged helix C-terminal ORC3_N PF07034.11 KKK17933.1 - 1.9e-21 76.5 0.0 3.4e-14 52.7 0.0 3.2 1 1 1 2 2 2 2 Origin recognition complex (ORC) subunit 3 N-terminus CTD_bind PF04818.13 KKK17934.1 - 2.5e-07 31.4 0.0 1e-06 29.4 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase II-binding domain. VHS PF00790.19 KKK17934.1 - 0.0029 17.5 0.0 0.004 17.0 0.0 1.3 1 0 0 1 1 1 1 VHS domain Inhibitor_I9 PF05922.16 KKK17935.1 - 0.044 14.5 0.0 0.046 14.4 0.0 1.2 1 0 0 1 1 1 0 Peptidase inhibitor I9 HOOK PF05622.12 KKK17936.1 - 9.3e-27 93.5 23.6 9.3e-27 93.5 23.6 3.8 2 1 1 3 3 3 2 HOOK protein DUF4407 PF14362.6 KKK17936.1 - 0.0035 16.8 9.8 0.0035 16.8 9.8 4.7 2 2 2 4 4 4 1 Domain of unknown function (DUF4407) CENP-F_leu_zip PF10473.9 KKK17936.1 - 0.072 13.1 69.5 0.74 9.8 11.3 6.6 4 1 2 6 6 6 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4710 PF15828.5 KKK17936.1 - 0.83 9.8 5.3 8.5 6.6 0.1 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4710) Fib_alpha PF08702.10 KKK17936.1 - 1.6 8.9 51.3 0.18 12.0 3.9 5.2 4 1 1 5 5 5 0 Fibrinogen alpha/beta chain family Pox_A_type_inc PF04508.12 KKK17936.1 - 2.3 8.2 16.1 16 5.5 0.3 6.0 5 0 0 5 5 5 0 Viral A-type inclusion protein repeat KASH_CCD PF14662.6 KKK17936.1 - 6.2 6.6 77.4 0.023 14.5 16.6 6.6 4 2 3 7 7 7 0 Coiled-coil region of CCDC155 or KASH V_ATPase_I PF01496.19 KKK17936.1 - 9.5 4.0 37.9 0.23 9.4 20.3 3.5 1 1 1 3 3 3 0 V-type ATPase 116kDa subunit family EB1 PF03271.17 KKK17937.1 - 4.9e-18 65.1 1.9 9.4e-18 64.2 1.9 1.5 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.31 KKK17937.1 - 5.4e-07 29.8 0.6 3e-06 27.4 0.4 1.9 2 0 0 2 2 2 1 Calponin homology (CH) domain Herpes_UL6 PF01763.16 KKK17937.1 - 0.012 14.2 0.0 0.022 13.3 0.0 1.4 2 0 0 2 2 2 0 Herpesvirus UL6 like Pkr1 PF08636.10 KKK17941.1 - 5.4e-31 106.6 4.5 1.4e-30 105.2 4.5 1.8 1 0 0 1 1 1 1 ER protein Pkr1 Cullin PF00888.22 KKK17941.1 - 3.8e-24 85.3 0.1 3.2e-23 82.2 0.1 2.1 2 0 0 2 2 2 1 Cullin family ANAPC2 PF08672.11 KKK17941.1 - 3.9e-23 81.7 0.0 9.8e-23 80.4 0.0 1.8 1 0 0 1 1 1 1 Anaphase promoting complex (APC) subunit 2 AAA_12 PF13087.6 KKK17942.1 - 4.1e-41 140.8 0.0 7.9e-41 139.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KKK17942.1 - 6.1e-27 95.0 0.1 4.5e-26 92.2 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KKK17942.1 - 6e-10 39.6 0.2 1.8e-08 34.8 0.1 3.0 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KKK17942.1 - 3.5e-08 33.4 0.3 0.0017 18.1 0.1 2.6 2 0 0 2 2 2 2 AAA domain DUF2075 PF09848.9 KKK17942.1 - 3.5e-05 23.2 0.2 0.2 10.9 0.0 2.4 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) ResIII PF04851.15 KKK17942.1 - 0.00056 19.9 0.0 0.0014 18.7 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.18 KKK17942.1 - 0.0015 18.3 0.3 0.95 9.2 0.0 3.0 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.6 KKK17942.1 - 0.0062 16.3 0.0 0.019 14.8 0.0 1.9 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Torus PF16131.5 KKK17942.1 - 0.21 12.3 0.8 1.3 9.7 0.2 2.3 2 0 0 2 2 2 0 Torus domain Pkinase PF00069.25 KKK17943.1 - 1.2e-66 224.8 0.0 1.8e-66 224.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK17943.1 - 1e-41 143.0 0.0 1.5e-41 142.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KKK17943.1 - 8.6e-09 35.1 0.0 3.2e-08 33.2 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 KKK17943.1 - 1.6e-06 27.4 0.3 1.6e-06 27.4 0.3 1.8 2 0 0 2 2 2 1 Haspin like kinase domain TMIE PF16038.5 KKK17943.1 - 0.057 13.3 0.1 0.057 13.3 0.1 2.0 2 0 0 2 2 2 0 TMIE protein Kdo PF06293.14 KKK17943.1 - 0.087 12.2 0.1 0.26 10.6 0.1 1.7 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ferlin_C PF16165.5 KKK17943.1 - 0.21 11.5 0.5 0.41 10.6 0.5 1.4 1 0 0 1 1 1 0 Ferlin C-terminus APH PF01636.23 KKK17943.1 - 0.44 10.4 4.4 1.2 9.0 0.1 2.8 2 1 1 3 3 3 0 Phosphotransferase enzyme family PRKG1_interact PF15898.5 KKK17943.1 - 0.82 10.6 10.4 0.056 14.4 4.4 2.2 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain Peptidase_C15 PF01470.17 KKK17945.1 - 1.1e-11 45.4 0.0 0.0022 18.2 0.0 3.1 2 1 1 3 3 3 3 Pyroglutamyl peptidase GATA PF00320.27 KKK17947.1 - 9.4e-16 57.1 2.4 1.6e-15 56.4 2.4 1.4 1 0 0 1 1 1 1 GATA zinc finger Pox_A_type_inc PF04508.12 KKK17947.1 - 0.0036 17.1 4.5 0.39 10.7 0.7 3.3 3 0 0 3 3 3 2 Viral A-type inclusion protein repeat CENP-F_N PF10481.9 KKK17947.1 - 0.015 14.9 0.9 0.72 9.4 0.0 2.2 2 0 0 2 2 2 0 Cenp-F N-terminal domain DivIVA PF05103.13 KKK17947.1 - 0.023 14.7 4.0 0.8 9.8 4.0 2.1 1 1 0 1 1 1 0 DivIVA protein TF_Zn_Ribbon PF08271.12 KKK17947.1 - 0.028 13.9 0.3 0.052 13.1 0.3 1.4 1 0 0 1 1 1 0 TFIIB zinc-binding GAS PF13851.6 KKK17947.1 - 0.063 12.6 1.9 0.095 12.0 1.9 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding ArfGap PF01412.18 KKK17947.1 - 0.096 12.8 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 Putative GTPase activating protein for Arf BBP1_C PF15272.6 KKK17947.1 - 0.12 12.2 1.1 0.19 11.6 1.1 1.3 1 0 0 1 1 1 0 Spindle pole body component BBP1, C-terminal CLZ PF16526.5 KKK17947.1 - 0.15 12.4 5.0 0.76 10.2 3.1 2.3 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels eIF-5_eIF-2B PF01873.17 KKK17947.1 - 0.16 11.8 0.2 0.28 11.1 0.2 1.4 1 0 0 1 1 1 0 Domain found in IF2B/IF5 Med21 PF11221.8 KKK17948.1 - 1.7e-57 193.7 2.2 3.3e-57 192.8 2.2 1.4 1 1 0 1 1 1 1 Subunit 21 of Mediator complex Med9 PF07544.13 KKK17948.1 - 0.013 15.6 3.2 0.051 13.7 0.2 2.5 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DUF4455 PF14643.6 KKK17948.1 - 0.064 11.9 0.3 0.089 11.4 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4455) Cortex-I_coil PF09304.10 KKK17948.1 - 0.23 11.7 4.3 1.2 9.4 4.3 2.0 1 1 0 1 1 1 0 Cortexillin I, coiled coil Spc24 PF08286.11 KKK17949.1 - 1.1e-36 125.2 1.0 4.1e-35 120.2 0.0 2.1 2 0 0 2 2 2 1 Spc24 subunit of Ndc80 CLZ PF16526.5 KKK17949.1 - 0.0042 17.4 6.2 0.19 12.1 1.7 2.3 2 0 0 2 2 2 2 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF4795 PF16043.5 KKK17949.1 - 0.035 13.7 2.1 0.077 12.6 2.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) Rx_N PF18052.1 KKK17949.1 - 0.56 10.5 3.9 6.9 7.0 0.8 2.2 2 0 0 2 2 2 0 Rx N-terminal domain SlyX PF04102.12 KKK17949.1 - 0.71 10.5 6.8 0.88 10.2 0.6 2.3 2 0 0 2 2 2 0 SlyX Prefoldin_2 PF01920.20 KKK17949.1 - 0.79 9.7 6.5 3.7 7.5 0.8 2.2 2 0 0 2 2 2 0 Prefoldin subunit TPR_MLP1_2 PF07926.12 KKK17949.1 - 1.5 8.9 10.5 0.27 11.3 2.6 2.0 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein APG6_N PF17675.1 KKK17949.1 - 2.1 8.9 9.8 3.2 8.3 9.8 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region DMPK_coil PF08826.10 KKK17949.1 - 3.8 7.7 10.9 1.4 9.1 1.6 2.2 2 0 0 2 2 2 0 DMPK coiled coil domain like HR1 PF02185.16 KKK17949.1 - 4.3 7.5 9.3 3.5 7.8 0.7 2.3 2 0 0 2 2 2 0 Hr1 repeat PI3_PI4_kinase PF00454.27 KKK17950.1 - 3.2e-24 86.1 0.0 5.6e-24 85.3 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase SNF2_N PF00176.23 KKK17951.1 - 7.5e-58 195.9 0.1 1.1e-57 195.4 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KKK17951.1 - 3.9e-13 49.7 0.0 4.6e-11 43.0 0.0 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KKK17951.1 - 2.9e-05 23.9 0.0 6.2e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KKK17951.1 - 0.0012 18.8 0.0 0.0027 17.7 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-RING_5 PF14634.6 KKK17951.1 - 0.014 15.3 1.0 0.024 14.6 1.0 1.4 1 0 0 1 1 1 0 zinc-RING finger domain DZR PF12773.7 KKK17951.1 - 1 9.4 2.5 2.3 8.3 2.5 1.5 1 0 0 1 1 1 0 Double zinc ribbon Fis1_TPR_C PF14853.6 KKK17952.1 - 1e-24 86.3 0.4 1.6e-24 85.7 0.4 1.3 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.6 KKK17952.1 - 3e-18 65.2 0.1 5.2e-18 64.4 0.1 1.4 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_2 PF07719.17 KKK17952.1 - 0.006 16.6 1.1 0.006 16.6 1.1 1.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 KKK17952.1 - 0.07 13.8 0.1 0.13 12.9 0.1 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat zf-RING_2 PF13639.6 KKK17953.1 - 1.5e-13 50.8 8.9 1.5e-13 50.8 8.9 2.3 2 0 0 2 2 2 1 Ring finger domain zf-RING_11 PF17123.5 KKK17953.1 - 5e-13 48.5 2.7 1.1e-12 47.4 2.7 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KKK17953.1 - 1.1e-09 38.0 9.0 1.1e-09 38.0 9.0 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KKK17953.1 - 4.9e-09 35.9 10.3 9.2e-08 31.8 4.2 2.2 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KKK17953.1 - 3.1e-06 27.0 7.8 3.1e-06 27.0 7.8 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KKK17953.1 - 3.4e-06 27.0 3.6 3.4e-06 27.0 3.6 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 KKK17953.1 - 1.4e-05 24.9 5.6 1.4e-05 24.9 5.6 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-rbx1 PF12678.7 KKK17953.1 - 1.6e-05 25.1 12.6 1.6e-05 25.1 12.6 2.1 2 1 0 2 2 2 1 RING-H2 zinc finger domain zinc_ribbon_9 PF14369.6 KKK17953.1 - 0.0004 20.6 6.2 0.01 16.0 2.8 2.6 2 0 0 2 2 2 1 zinc-ribbon Prok-RING_4 PF14447.6 KKK17953.1 - 0.00042 20.1 6.3 0.00042 20.1 6.3 2.3 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 KKK17953.1 - 0.00099 19.1 3.3 0.00099 19.1 3.3 1.8 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger HypA PF01155.19 KKK17953.1 - 0.0081 16.2 6.0 0.017 15.1 0.3 2.2 2 0 0 2 2 2 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-UDP PF14569.6 KKK17953.1 - 0.021 14.9 3.3 0.62 10.2 0.5 2.6 2 0 0 2 2 2 0 Zinc-binding RING-finger DZR PF12773.7 KKK17953.1 - 0.034 14.2 7.0 1.3 9.1 0.4 2.4 2 0 0 2 2 2 0 Double zinc ribbon Rad50_zn_hook PF04423.14 KKK17953.1 - 0.23 11.4 1.2 13 5.7 0.0 2.4 2 0 0 2 2 2 0 Rad50 zinc hook motif zinc-ribbons_6 PF07191.12 KKK17953.1 - 0.48 10.4 7.4 3.3 7.8 0.1 2.8 2 1 0 2 2 2 0 zinc-ribbons zinc_ribbon_4 PF13717.6 KKK17953.1 - 0.92 9.5 6.7 35 4.4 0.0 4.0 4 0 0 4 4 4 0 zinc-ribbon domain TF_Zn_Ribbon PF08271.12 KKK17953.1 - 1.3 8.5 4.1 25 4.5 0.0 3.1 3 0 0 3 3 3 0 TFIIB zinc-binding zf-C2HC5 PF06221.13 KKK17953.1 - 1.4 8.9 4.8 2.9 7.9 0.2 2.7 3 0 0 3 3 3 0 Putative zinc finger motif, C2HC5-type zf-RING_4 PF14570.6 KKK17953.1 - 1.7 8.5 12.8 0.2 11.5 4.4 2.4 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.8 KKK17953.1 - 1.8 8.8 9.5 1.3 9.3 6.0 2.5 2 1 0 2 2 2 0 FANCL C-terminal domain TackOD1 PF18551.1 KKK17953.1 - 1.9 8.1 7.2 3.4 7.3 0.3 2.4 2 1 0 2 2 2 0 Thaumarchaeal output domain 1 Zn_ribbon_17 PF17120.5 KKK17953.1 - 2.7 7.7 15.2 0.066 12.8 7.7 2.0 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type PHD PF00628.29 KKK17953.1 - 4 7.4 14.4 0.99 9.4 7.2 2.4 2 0 0 2 2 2 0 PHD-finger PQ-loop PF04193.14 KKK17954.1 - 1.4e-30 104.8 6.4 8.5e-18 63.9 1.2 2.4 2 0 0 2 2 2 2 PQ loop repeat APH PF01636.23 KKK17955.1 - 3e-16 60.1 0.1 1.1e-15 58.3 0.1 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.14 KKK17955.1 - 0.015 14.5 0.0 0.033 13.4 0.0 1.5 1 0 0 1 1 1 0 Fructosamine kinase Dicty_REP PF05086.12 KKK17957.1 - 0.063 11.3 0.9 0.074 11.0 0.9 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Importin_rep PF18773.1 KKK17961.1 - 8.2e-07 28.6 0.0 1.9e-06 27.5 0.0 1.7 1 0 0 1 1 1 1 Importin 13 repeat Importin_rep_3 PF18806.1 KKK17961.1 - 4.8e-06 26.5 0.0 1.6e-05 24.8 0.0 1.9 1 0 0 1 1 1 1 Importin 13 repeat IBN_N PF03810.19 KKK17961.1 - 1e-05 25.3 0.1 3.7e-05 23.6 0.1 2.0 1 0 0 1 1 1 1 Importin-beta N-terminal domain Creatinase_N_2 PF16189.5 KKK17962.1 - 4.1e-54 183.0 0.0 2.3e-52 177.3 0.0 2.3 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain Peptidase_M24 PF00557.24 KKK17962.1 - 6e-44 150.2 0.0 8.5e-44 149.7 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Peptidase_M24_C PF16188.5 KKK17962.1 - 8.2e-23 80.3 0.4 1.8e-22 79.1 0.4 1.6 1 0 0 1 1 1 1 C-terminal region of peptidase_M24 Creatinase_N PF01321.18 KKK17962.1 - 1.2e-18 68.0 0.0 1.2e-15 58.3 0.0 2.5 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain Sec8_exocyst PF04048.14 KKK17963.1 - 2.7e-49 166.7 4.6 4.5e-49 166.0 3.1 2.2 2 0 0 2 2 2 1 Sec8 exocyst complex component specific domain Vps54_N PF10475.9 KKK17963.1 - 2.6e-08 33.5 2.2 5e-08 32.6 2.2 1.3 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex Zw10 PF06248.13 KKK17963.1 - 2.1e-05 23.3 0.5 3.7e-05 22.5 0.5 1.3 1 0 0 1 1 1 1 Centromere/kinetochore Zw10 Sec5 PF15469.6 KKK17963.1 - 0.00069 19.5 1.5 0.0016 18.3 1.5 1.5 1 0 0 1 1 1 1 Exocyst complex component Sec5 Dor1 PF04124.12 KKK17963.1 - 0.014 14.1 6.3 0.02 13.6 4.8 1.9 2 0 0 2 2 2 0 Dor1-like family Occludin_ELL PF07303.13 KKK17963.1 - 0.048 14.4 0.3 0.38 11.5 0.5 2.5 2 0 0 2 2 2 0 Occludin homology domain FliJ PF02050.16 KKK17963.1 - 0.13 12.5 5.9 1.8 8.8 0.1 2.7 2 1 0 2 2 2 0 Flagellar FliJ protein Spc7 PF08317.11 KKK17963.1 - 0.14 11.0 2.2 0.28 10.0 2.2 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein DPBB_1 PF03330.18 KKK17964.1 - 9.7e-09 35.4 0.1 9.7e-09 35.4 0.1 2.7 3 1 0 3 3 3 1 Lytic transglycolase Pollen_allerg_1 PF01357.21 KKK17964.1 - 0.00026 20.9 0.3 0.00089 19.2 0.3 1.9 1 0 0 1 1 1 1 Pollen allergen HLH PF00010.26 KKK17965.1 - 1.2e-12 47.5 2.0 1.2e-12 47.5 2.0 1.8 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain SAC3_GANP PF03399.16 KKK17966.1 - 3.1e-101 338.6 0.3 4.1e-101 338.2 0.3 1.1 1 0 0 1 1 1 1 SAC3/GANP family CN_hydrolase PF00795.22 KKK17966.1 - 1.3e-11 44.4 0.0 3.1e-11 43.1 0.0 1.6 2 0 0 2 2 2 1 Carbon-nitrogen hydrolase CSN8_PSD8_EIF3K PF10075.9 KKK17966.1 - 0.0096 15.9 0.0 0.027 14.4 0.0 1.7 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family MUG113 PF13455.6 KKK17967.1 - 1.3e-27 96.2 0.0 2.7e-27 95.3 0.0 1.5 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 T5orf172 PF10544.9 KKK17967.1 - 5.2e-26 91.2 0.0 1.5e-25 89.7 0.0 1.8 1 0 0 1 1 1 1 T5orf172 domain TOM6p PF15184.6 KKK17967.1 - 0.028 14.2 0.1 0.059 13.1 0.1 1.5 1 0 0 1 1 1 0 Mitochondrial import receptor subunit TOM6 homolog DUF1631 PF07793.11 KKK17967.1 - 0.27 9.6 2.9 0.37 9.2 2.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) ATG101 PF07855.12 KKK17971.1 - 6.5e-54 182.1 0.0 7.5e-54 181.9 0.0 1.0 1 0 0 1 1 1 1 Autophagy-related protein 101 Peroxin-3 PF04882.12 KKK17972.1 - 4.6e-164 546.9 0.5 5.4e-164 546.6 0.5 1.0 1 0 0 1 1 1 1 Peroxin-3 MFS_1 PF07690.16 KKK17973.1 - 4.9e-35 121.1 29.8 7.9e-35 120.4 29.8 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily RNA_pol_I_A49 PF06870.12 KKK17974.1 - 4e-75 253.1 0.0 7.8e-75 252.1 0.0 1.4 1 1 0 1 1 1 1 A49-like RNA polymerase I associated factor NOT2_3_5 PF04153.18 KKK17980.1 - 8.6e-27 93.8 0.1 3.1e-26 92.0 0.0 1.9 2 0 0 2 2 2 1 NOT2 / NOT3 / NOT5 family MRP-L47 PF06984.13 KKK17981.1 - 1.3e-19 70.1 0.2 1.9e-19 69.6 0.2 1.2 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Clc-like PF07062.12 KKK17981.1 - 0.45 9.9 2.8 0.77 9.2 2.8 1.4 1 0 0 1 1 1 0 Clc-like SMC_N PF02463.19 KKK17982.1 - 1.2e-59 201.4 4.3 5e-59 199.4 4.3 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KKK17982.1 - 1.3e-22 80.3 1.1 1.1e-21 77.3 0.2 2.8 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.6 KKK17982.1 - 5.6e-13 49.8 5.1 5.6e-13 49.8 5.1 6.4 2 2 2 4 4 4 1 AAA domain CUE PF02845.16 KKK17982.1 - 4.3e-11 42.3 0.0 1.8e-10 40.3 0.0 2.2 1 0 0 1 1 1 1 CUE domain AAA_21 PF13304.6 KKK17982.1 - 1.9e-09 37.8 6.4 0.00025 21.0 0.1 4.3 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system HIP1_clath_bdg PF16515.5 KKK17982.1 - 9.3e-05 23.0 9.1 9.3e-05 23.0 9.1 9.7 3 2 8 11 11 11 1 Clathrin-binding domain of Huntingtin-interacting protein 1 AAA_29 PF13555.6 KKK17982.1 - 0.00016 21.4 0.1 0.00038 20.1 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain ApbA_C PF08546.11 KKK17982.1 - 0.79 9.9 4.9 3.3 7.9 0.4 3.1 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA C terminal G2BR PF18442.1 KKK17982.1 - 5.9 6.6 18.3 1 9.0 12.8 2.5 2 0 0 2 2 2 0 E3 gp78 Ube2g2-binding region (G2BR) Tyr-DNA_phospho PF06087.12 KKK17983.1 - 3.5e-164 546.7 0.0 4.3e-164 546.4 0.0 1.1 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase DIE2_ALG10 PF04922.12 KKK17983.1 - 1.1e-124 416.7 5.9 1.5e-124 416.3 5.9 1.2 1 0 0 1 1 1 1 DIE2/ALG10 family PLDc_2 PF13091.6 KKK17983.1 - 0.14 12.0 0.0 4.6 7.1 0.0 2.3 2 0 0 2 2 2 0 PLD-like domain Sld5 PF05916.11 KKK17984.1 - 1.5e-36 125.2 0.0 3.2e-36 124.1 0.0 1.6 1 1 0 1 1 1 1 GINS complex protein U-box PF04564.15 KKK17985.1 - 4.9e-21 74.7 0.0 1.1e-20 73.6 0.0 1.6 1 0 0 1 1 1 1 U-box domain TPR_2 PF07719.17 KKK17985.1 - 2.9e-07 30.1 5.7 0.00034 20.5 0.1 4.3 4 1 0 4 4 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KKK17985.1 - 2.5e-06 27.1 6.0 8.3e-05 22.2 0.2 3.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 KKK17985.1 - 5.2e-05 23.7 4.6 0.13 12.8 0.5 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 KKK17985.1 - 8.3e-05 22.2 1.9 0.00051 19.7 0.0 2.8 3 0 0 3 3 3 1 TPR repeat ANAPC3 PF12895.7 KKK17985.1 - 0.00041 20.5 0.3 0.0089 16.2 0.2 2.3 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 KKK17985.1 - 0.0016 18.7 0.7 1.6 9.2 0.1 3.0 2 1 1 3 3 3 2 Tetratricopeptide repeat CHIP_TPR_N PF18391.1 KKK17985.1 - 0.0026 18.5 2.3 0.0047 17.7 2.3 1.4 1 0 0 1 1 1 1 CHIP N-terminal tetratricopeptide repeat domain TPR_14 PF13428.6 KKK17985.1 - 0.0028 18.3 6.9 1.1 10.3 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 KKK17985.1 - 0.0097 16.2 7.0 0.16 12.3 0.6 3.0 3 1 0 3 3 2 2 Tetratricopeptide repeat GlnD_UR_UTase PF08335.11 KKK17985.1 - 0.017 15.3 2.7 0.026 14.6 2.7 1.2 1 0 0 1 1 1 0 GlnD PII-uridylyltransferase GvpG PF05120.12 KKK17985.1 - 0.019 15.0 0.6 0.042 13.9 0.6 1.6 1 0 0 1 1 1 0 Gas vesicle protein G TPR_16 PF13432.6 KKK17985.1 - 0.025 15.2 9.0 3.4 8.4 0.0 3.4 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 KKK17985.1 - 0.2 11.8 3.5 2.7 8.2 0.0 3.4 3 1 0 3 3 3 0 Tetratricopeptide repeat ACBP PF00887.19 KKK17986.1 - 6.1e-17 61.6 1.1 1e-16 60.9 1.1 1.4 1 0 0 1 1 1 1 Acyl CoA binding protein Methyltransf_25 PF13649.6 KKK17987.1 - 6.9e-09 36.3 0.0 1.2e-08 35.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KKK17987.1 - 3.3e-05 23.3 0.0 5.1e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 KKK17987.1 - 0.00053 20.6 0.0 0.00093 19.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KKK17987.1 - 0.002 18.0 0.0 0.0035 17.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KKK17987.1 - 0.0063 17.2 0.0 0.01 16.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain ORC4_C PF14629.6 KKK17988.1 - 5.9e-51 172.9 0.0 8.7e-51 172.4 0.0 1.3 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.6 KKK17988.1 - 1.7e-13 51.3 0.0 5.9e-13 49.5 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain DUF815 PF05673.13 KKK17988.1 - 2.6e-06 26.8 0.1 4.8e-06 25.9 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 KKK17988.1 - 1.4e-05 25.4 0.0 3.7e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 KKK17988.1 - 7.3e-05 23.2 0.0 0.00029 21.3 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) KAP_NTPase PF07693.14 KKK17988.1 - 0.0003 20.1 0.0 0.00062 19.1 0.0 1.4 1 0 0 1 1 1 1 KAP family P-loop domain NACHT PF05729.12 KKK17988.1 - 0.002 18.1 1.8 0.0093 15.9 0.6 2.7 2 1 0 2 2 2 1 NACHT domain AAA_29 PF13555.6 KKK17988.1 - 0.0076 16.0 0.1 0.02 14.6 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain ATPase_2 PF01637.18 KKK17988.1 - 0.028 14.3 0.1 0.12 12.2 0.1 1.9 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_19 PF13245.6 KKK17988.1 - 0.038 14.3 0.0 0.082 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KKK17988.1 - 0.042 13.4 0.1 0.089 12.3 0.1 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region ThiS-like PF14453.6 KKK17988.1 - 0.065 13.3 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 ThiS-like ubiquitin ABC_tran PF00005.27 KKK17988.1 - 0.12 12.9 0.0 0.55 10.7 0.0 2.1 2 0 0 2 2 2 0 ABC transporter NB-ARC PF00931.22 KKK17988.1 - 0.18 11.0 0.1 0.32 10.1 0.1 1.3 1 0 0 1 1 1 0 NB-ARC domain PIF1 PF05970.14 KKK17988.1 - 0.2 10.8 0.1 0.34 10.0 0.1 1.3 1 0 0 1 1 1 0 PIF1-like helicase Zn_clus PF00172.18 KKK17989.1 - 1.8e-11 44.0 10.9 3.3e-11 43.1 10.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KKK17989.1 - 3.9e-10 39.1 0.2 6.2e-10 38.4 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain 4HBT PF03061.22 KKK17990.1 - 1.1e-10 41.7 0.2 1.6e-10 41.2 0.2 1.2 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.6 KKK17990.1 - 0.037 14.3 0.0 0.052 13.8 0.0 1.2 1 0 0 1 1 1 0 Thioesterase-like superfamily GDI PF00996.18 KKK17991.1 - 1e-192 640.5 0.0 1.1e-192 640.3 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor NAD_binding_8 PF13450.6 KKK17991.1 - 0.02 15.1 0.0 0.045 14.0 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KKK17991.1 - 0.034 14.7 0.3 1.7 9.3 0.1 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Vma12 PF11712.8 KKK17992.1 - 2.6e-40 137.7 0.0 3.6e-40 137.2 0.0 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase CHCH PF06747.13 KKK17995.1 - 3.7e-08 33.3 4.8 6.7e-08 32.5 4.8 1.5 1 0 0 1 1 1 1 CHCH domain GCK PF07802.11 KKK17995.1 - 0.00069 20.0 1.2 0.0013 19.1 1.2 1.5 1 0 0 1 1 1 1 GCK domain ABC_tran PF00005.27 KKK17996.1 - 4.4e-47 160.0 0.4 3.1e-24 86.0 0.0 4.3 3 2 0 3 3 2 2 ABC transporter 4HB PF17947.1 KKK17996.1 - 1.5e-30 105.0 2.4 2.5e-30 104.4 0.8 2.3 2 0 0 2 2 1 1 Four helical bundle domain AAA_21 PF13304.6 KKK17996.1 - 1.1e-16 61.6 0.3 0.0022 17.8 0.0 5.1 6 0 0 6 6 5 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KKK17996.1 - 1.1e-15 57.7 0.0 8.3e-06 25.4 0.0 3.6 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KKK17996.1 - 1.9e-09 38.3 2.9 0.00048 20.7 0.1 2.9 3 0 0 3 3 2 2 AAA domain AAA_29 PF13555.6 KKK17996.1 - 6.6e-08 32.2 0.1 0.0095 15.7 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_28 PF13521.6 KKK17996.1 - 1.1e-07 32.2 0.0 0.016 15.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 KKK17996.1 - 1.3e-06 28.5 0.0 0.0012 18.8 0.0 2.6 2 0 0 2 2 2 1 RsgA GTPase PduV-EutP PF10662.9 KKK17996.1 - 1.3e-06 28.2 0.0 0.063 13.0 0.0 2.8 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.6 KKK17996.1 - 2.2e-06 28.2 0.0 0.076 13.4 0.0 3.7 2 1 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.23 KKK17996.1 - 3.4e-06 27.1 0.2 0.0053 16.8 0.0 3.4 4 0 0 4 4 2 1 50S ribosome-binding GTPase AAA_22 PF13401.6 KKK17996.1 - 4.6e-06 27.0 0.1 0.084 13.1 0.0 3.6 4 0 0 4 4 2 2 AAA domain AAA PF00004.29 KKK17996.1 - 8.6e-06 26.2 0.0 0.17 12.3 0.1 4.2 4 1 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 KKK17996.1 - 1.6e-05 25.4 0.1 0.36 11.4 0.0 3.1 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 KKK17996.1 - 0.00012 22.5 0.0 0.65 10.4 0.0 2.6 2 0 0 2 2 2 2 RNA helicase AAA_27 PF13514.6 KKK17996.1 - 0.00017 21.2 0.0 0.13 11.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KKK17996.1 - 0.00029 20.8 0.0 0.21 11.5 0.0 2.7 2 0 0 2 2 2 1 NACHT domain Dynamin_N PF00350.23 KKK17996.1 - 0.0004 20.5 0.5 0.0018 18.3 0.0 2.4 3 0 0 3 3 2 1 Dynamin family AAA_14 PF13173.6 KKK17996.1 - 0.00044 20.3 0.0 0.62 10.1 0.0 2.8 3 0 0 3 3 2 1 AAA domain AAA_24 PF13479.6 KKK17996.1 - 0.00045 20.0 0.0 1.5 8.5 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_15 PF13175.6 KKK17996.1 - 0.00047 20.0 3.1 1 9.0 0.1 3.6 3 2 1 5 5 3 2 AAA ATPase domain AAA_33 PF13671.6 KKK17996.1 - 0.0006 20.0 0.0 0.75 9.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.17 KKK17996.1 - 0.00089 19.4 2.6 0.14 12.2 0.0 3.3 4 0 0 4 4 2 1 Helicase HerA, central domain AAA_13 PF13166.6 KKK17996.1 - 0.00096 17.9 0.0 0.22 10.1 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_30 PF13604.6 KKK17996.1 - 0.0011 18.7 0.0 1 9.0 0.0 3.0 3 0 0 3 3 3 1 AAA domain G-alpha PF00503.20 KKK17996.1 - 0.0014 17.9 0.1 1.6 7.8 0.0 2.4 2 0 0 2 2 2 2 G-protein alpha subunit HEAT_2 PF13646.6 KKK17996.1 - 0.0016 18.8 0.1 1.4 9.3 0.0 2.9 1 1 1 2 2 2 1 HEAT repeats cobW PF02492.19 KKK17996.1 - 0.002 17.8 0.1 1.4 8.4 0.0 3.2 4 0 0 4 4 3 1 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 KKK17996.1 - 0.0023 17.0 0.1 1.1 8.1 0.0 2.5 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB HEAT PF02985.22 KKK17996.1 - 0.0024 18.0 2.2 7.8 7.0 0.0 5.2 5 0 0 5 5 4 0 HEAT repeat ATP_bind_1 PF03029.17 KKK17996.1 - 0.0045 16.8 0.1 3.4 7.4 0.0 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein ATPase_2 PF01637.18 KKK17996.1 - 0.0054 16.7 0.0 0.89 9.4 0.0 2.9 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea Roc PF08477.13 KKK17996.1 - 0.0059 16.8 0.0 4.7 7.5 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase NB-ARC PF00931.22 KKK17996.1 - 0.0078 15.4 0.1 0.21 10.8 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain AAA_5 PF07728.14 KKK17996.1 - 0.011 15.7 0.0 13 5.8 0.0 3.6 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) SbcCD_C PF13558.6 KKK17996.1 - 0.011 15.9 0.0 2.4 8.5 0.0 2.9 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_7 PF12775.7 KKK17996.1 - 0.018 14.6 0.1 3.3 7.2 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region T2SSE PF00437.20 KKK17996.1 - 0.018 14.1 0.1 6.6 5.7 0.0 3.0 3 0 0 3 3 3 0 Type II/IV secretion system protein Mg_chelatase PF01078.21 KKK17996.1 - 0.02 14.3 0.1 3.4 7.0 0.0 3.0 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI TsaE PF02367.17 KKK17996.1 - 0.02 14.9 0.0 5.1 7.1 0.0 2.7 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE MMS19_C PF12460.8 KKK17996.1 - 0.021 13.9 0.0 2.6 7.0 0.0 2.6 2 0 0 2 2 2 0 RNAPII transcription regulator C-terminal ATP-synt_ab PF00006.25 KKK17996.1 - 0.03 14.0 0.0 2.6 7.7 0.0 2.6 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_25 PF13481.6 KKK17996.1 - 0.04 13.5 0.0 3.6 7.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 KKK17996.1 - 0.043 13.6 0.0 11 5.7 0.0 2.6 2 0 0 2 2 2 0 IstB-like ATP binding protein Rad17 PF03215.15 KKK17996.1 - 0.051 13.5 0.0 1.1 9.1 0.0 2.3 2 0 0 2 2 2 0 Rad17 P-loop domain Septin PF00735.18 KKK17996.1 - 0.056 12.7 0.2 3.6 6.8 0.0 2.6 3 0 0 3 3 2 0 Septin Arf PF00025.21 KKK17996.1 - 0.089 12.2 0.0 13 5.2 0.0 2.6 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA_19 PF13245.6 KKK17996.1 - 0.095 13.0 0.0 39 4.6 0.0 3.1 3 0 0 3 3 3 0 AAA domain NTPase_1 PF03266.15 KKK17996.1 - 0.096 12.6 0.2 15 5.4 0.1 2.7 2 0 0 2 2 2 0 NTPase dNK PF01712.19 KKK17996.1 - 0.12 12.2 0.0 2.4 7.9 0.0 2.3 2 0 0 2 2 2 0 Deoxynucleoside kinase PRK PF00485.18 KKK17996.1 - 0.13 12.0 0.0 6.3 6.5 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family RuvB_N PF05496.12 KKK17996.1 - 0.13 12.0 0.3 18 5.0 0.0 2.9 3 0 0 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain MukB PF04310.12 KKK17996.1 - 0.16 11.7 0.0 24 4.6 0.0 2.4 2 0 0 2 2 2 0 MukB N-terminal CLP1_P PF16575.5 KKK17996.1 - 0.4 10.4 4.6 2.6 7.8 0.0 3.3 4 0 0 4 4 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop HEAT_EZ PF13513.6 KKK17996.1 - 5.6 7.6 7.0 64 4.2 0.0 4.7 3 2 2 5 5 4 0 HEAT-like repeat DRY_EERY PF09750.9 KKK17997.1 - 0.069 13.4 0.3 0.13 12.5 0.3 1.4 1 0 0 1 1 1 0 Alternative splicing regulator MIF4G PF02854.19 KKK17998.1 - 5.9e-58 196.0 0.1 5.1e-33 114.5 0.0 3.7 4 0 0 4 4 4 2 MIF4G domain Upf2 PF04050.14 KKK17998.1 - 8.3e-42 143.1 10.2 8.3e-42 143.1 10.2 2.2 3 0 0 3 3 3 1 Up-frameshift suppressor 2 ETF PF01012.21 KKK17999.1 - 1.5e-43 148.8 5.0 2.9e-43 147.9 5.0 1.5 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ETF_alpha PF00766.19 KKK17999.1 - 1.7e-32 111.3 0.2 4.2e-32 110.0 0.2 1.7 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain SUN PF03856.13 KKK18000.1 - 1.7e-92 309.3 12.6 3.5e-92 308.3 12.6 1.5 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) FSA_C PF10479.9 KKK18000.1 - 0.06 11.5 20.9 0.089 10.9 20.9 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus PRCC PF10253.9 KKK18000.1 - 0.19 12.5 3.8 0.27 12.0 3.8 1.3 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting RIFIN PF02009.16 KKK18000.1 - 3 7.7 5.7 4 7.2 5.7 1.2 1 0 0 1 1 1 0 Rifin Ribosomal_L1 PF00687.21 KKK18001.1 - 4.1e-62 209.5 5.2 4.1e-62 209.5 5.2 1.6 2 0 0 2 2 2 1 Ribosomal protein L1p/L10e family EF-hand_6 PF13405.6 KKK18002.1 - 9.8e-13 46.9 2.0 6.6e-06 25.7 0.3 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 KKK18002.1 - 8.4e-12 43.8 2.8 1.1e-05 24.6 0.7 2.7 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 KKK18002.1 - 9.3e-10 38.8 4.7 2e-08 34.5 0.8 2.2 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 KKK18002.1 - 7.8e-08 31.5 5.9 0.0033 16.8 1.3 2.4 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 KKK18002.1 - 1.7e-06 27.8 0.3 0.047 13.5 0.1 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.6 KKK18002.1 - 0.0028 17.9 0.1 2.8 8.3 0.0 2.6 2 1 0 2 2 2 2 EF-hand domain DUF4398 PF14346.6 KKK18002.1 - 0.057 14.0 0.3 0.057 14.0 0.3 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4398) RabGAP-TBC PF00566.18 KKK18003.1 - 2.7e-16 59.9 0.0 2.7e-11 43.6 0.0 2.2 2 0 0 2 2 2 2 Rab-GTPase-TBC domain RRM_1 PF00076.22 KKK18004.1 - 2.9e-18 65.4 0.0 5.7e-14 51.7 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) X8 PF07983.13 KKK18007.1 - 8e-27 93.7 5.0 2e-26 92.5 5.0 1.7 1 0 0 1 1 1 1 X8 domain Sugar_tr PF00083.24 KKK18020.1 - 2e-07 30.3 1.2 2.4e-07 30.0 1.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter V-SNARE_C PF12352.8 KKK18020.1 - 0.015 15.6 0.0 0.022 15.1 0.0 1.2 1 0 0 1 1 1 0 Snare region anchored in the vesicle membrane C-terminus tRNA-synt_1 PF00133.22 KKK18054.1 - 2.7e-165 551.0 0.0 3.5e-165 550.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KKK18054.1 - 7.4e-22 77.9 1.0 1.4e-21 77.0 1.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 KKK18054.1 - 5.8e-21 74.7 0.0 3.1e-13 49.3 0.0 4.1 3 1 0 3 3 3 3 tRNA synthetases class I (M) zf-FPG_IleRS PF06827.14 KKK18054.1 - 0.00037 20.3 3.4 0.0022 17.8 3.0 2.4 2 0 0 2 2 2 1 Zinc finger found in FPG and IleRS tRNA-synt_1_2 PF13603.6 KKK18054.1 - 0.061 12.8 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 KKK18054.1 - 0.061 12.7 0.0 10 5.4 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain TF_Zn_Ribbon PF08271.12 KKK18054.1 - 0.094 12.2 1.2 0.18 11.4 1.2 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding UPF0183 PF03676.14 KKK18055.1 - 1.8e-49 169.1 0.0 1.9e-31 109.8 0.0 2.9 2 1 0 2 2 2 2 Uncharacterised protein family (UPF0183) Kinesin PF00225.23 KKK18056.1 - 9.3e-112 373.2 2.0 2.6e-111 371.8 2.0 1.8 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KKK18056.1 - 8.7e-24 84.1 0.1 4.6e-23 81.8 0.1 2.3 1 0 0 1 1 1 1 Microtubule binding Microtub_bind PF13931.6 KKK18056.1 - 1.5e-09 38.3 3.6 1.5e-09 38.3 3.6 5.3 4 2 2 6 6 6 1 Kinesin-associated microtubule-binding Baculo_PEP_C PF04513.12 KKK18056.1 - 0.00026 21.1 31.8 0.00035 20.6 0.2 5.8 1 1 2 5 5 5 3 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.12 KKK18056.1 - 0.59 10.2 44.2 0.19 11.8 0.2 7.1 3 2 5 8 8 8 0 Protein of unknown function (DUF1664) HWE_HK PF07536.14 KKK18056.1 - 0.81 10.4 6.7 5.1 7.9 0.2 4.1 3 0 0 3 3 3 0 HWE histidine kinase DUF1515 PF07439.11 KKK18056.1 - 1 9.4 15.8 0.31 11.1 2.1 4.9 3 3 0 3 3 3 0 Protein of unknown function (DUF1515) Plasmid_RAQPRD PF09686.10 KKK18056.1 - 2.9 8.2 12.4 4.8 7.5 0.0 5.0 4 1 1 5 5 5 0 Plasmid protein of unknown function (Plasmid_RAQPRD) ABC_tran PF00005.27 KKK18058.1 - 5.3e-47 159.8 0.0 7e-30 104.3 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KKK18058.1 - 1.5e-36 126.4 37.4 1e-24 87.7 15.1 3.4 4 1 1 5 5 5 2 ABC transporter transmembrane region SMC_N PF02463.19 KKK18058.1 - 6.6e-12 45.3 0.1 0.0011 18.4 0.0 4.3 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KKK18058.1 - 1.2e-05 25.9 0.1 0.019 15.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 KKK18058.1 - 3.5e-05 24.1 0.1 0.2 12.0 0.0 3.2 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KKK18058.1 - 0.00031 20.4 0.4 0.36 10.6 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 KKK18058.1 - 0.00072 20.0 1.1 0.2 12.0 0.1 3.0 2 0 0 2 2 2 1 AAA ATPase domain MMR_HSR1 PF01926.23 KKK18058.1 - 0.0012 18.9 0.0 0.083 13.0 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase T2SSE PF00437.20 KKK18058.1 - 0.0012 18.0 0.0 0.3 10.1 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein RsgA_GTPase PF03193.16 KKK18058.1 - 0.0054 16.7 0.0 2.8 7.8 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase IstB_IS21 PF01695.17 KKK18058.1 - 0.0081 15.9 0.0 0.13 12.0 0.0 2.6 2 0 0 2 2 2 1 IstB-like ATP binding protein DUF87 PF01935.17 KKK18058.1 - 0.013 15.6 2.1 0.37 10.9 0.1 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain DUF2075 PF09848.9 KKK18058.1 - 0.013 14.7 0.0 0.7 9.1 0.0 2.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_25 PF13481.6 KKK18058.1 - 0.02 14.5 0.0 3 7.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 KKK18058.1 - 0.12 11.6 0.2 22 4.1 0.0 2.9 3 0 0 3 3 3 0 NB-ARC domain Zeta_toxin PF06414.12 KKK18058.1 - 0.13 11.5 0.1 14 4.9 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin MeaB PF03308.16 KKK18058.1 - 0.17 10.8 0.0 0.35 9.8 0.0 1.5 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Beta_helix PF13229.6 KKK18059.1 - 7.3 6.4 18.7 0.17 11.7 3.4 3.3 2 1 1 3 3 3 0 Right handed beta helix region AA_permease PF00324.21 KKK18060.1 - 1.1e-109 367.3 39.3 1.2e-109 367.1 39.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KKK18060.1 - 1.1e-27 96.9 41.8 1.4e-27 96.6 41.8 1.1 1 0 0 1 1 1 1 Amino acid permease Bac_rhodopsin PF01036.18 KKK18061.1 - 5.7e-34 117.6 15.0 7.1e-34 117.3 15.0 1.1 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein Mucin PF01456.17 KKK18061.1 - 0.19 11.7 11.1 0.36 10.8 11.1 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein zf-ANAPC11 PF12861.7 KKK18062.1 - 7.7e-47 157.3 10.6 8.7e-47 157.1 10.6 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 KKK18062.1 - 1.2e-21 76.8 10.3 1.5e-21 76.4 10.3 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 KKK18062.1 - 1.1e-08 35.2 15.5 3.4e-07 30.5 15.5 2.5 1 1 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KKK18062.1 - 3.5e-05 23.7 9.8 0.00013 21.9 5.5 2.5 2 1 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KKK18062.1 - 8.5e-05 22.3 5.4 8.5e-05 22.3 5.4 2.5 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 KKK18062.1 - 0.0003 20.5 11.3 0.021 14.6 8.7 2.7 1 1 1 2 2 2 1 RING/Ubox like zinc-binding domain zf-C3HC4 PF00097.25 KKK18062.1 - 0.0012 18.6 13.8 0.0046 16.8 13.8 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KKK18062.1 - 0.0012 18.6 12.5 0.002 17.9 7.4 2.3 1 1 2 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KKK18062.1 - 0.0014 18.8 1.8 0.0014 18.8 1.8 2.3 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING FANCL_C PF11793.8 KKK18062.1 - 0.0017 18.5 15.6 0.038 14.2 15.6 3.1 1 1 0 1 1 1 1 FANCL C-terminal domain Prok-RING_4 PF14447.6 KKK18062.1 - 0.014 15.2 2.9 0.014 15.2 2.9 2.5 1 1 2 3 3 3 0 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KKK18062.1 - 0.017 15.1 16.6 0.19 11.7 17.0 2.6 1 1 1 2 2 2 0 zinc-RING finger domain zf-HIT PF04438.16 KKK18062.1 - 0.027 14.4 3.5 0.077 12.9 0.6 2.4 2 0 0 2 2 2 0 HIT zinc finger Rad50_zn_hook PF04423.14 KKK18062.1 - 0.049 13.5 1.3 0.74 9.7 0.0 2.4 2 0 0 2 2 2 0 Rad50 zinc hook motif Zn_ribbon_17 PF17120.5 KKK18062.1 - 0.06 13.0 13.1 0.13 11.9 11.2 2.2 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type YacG PF03884.14 KKK18062.1 - 0.26 11.0 0.3 0.26 11.0 0.3 2.8 3 0 0 3 3 3 0 DNA gyrase inhibitor YacG zf-C2H2_9 PF16293.5 KKK18062.1 - 0.55 10.1 6.1 4.4 7.2 0.1 3.1 2 1 0 2 2 2 0 C2H2 type zinc-finger (1 copy) zf-Nse PF11789.8 KKK18062.1 - 0.57 10.0 5.8 1.1 9.1 5.8 1.6 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit PHD PF00628.29 KKK18062.1 - 0.71 9.8 13.6 3.6 7.6 13.6 2.1 1 1 0 1 1 1 0 PHD-finger zf-RING_11 PF17123.5 KKK18062.1 - 1.9 8.3 13.8 3.2 7.6 10.6 2.7 2 1 0 2 2 2 0 RING-like zinc finger zf-RING-like PF08746.11 KKK18062.1 - 3.8 7.9 12.6 23 5.4 12.6 2.2 1 1 0 1 1 1 0 RING-like domain RINGv PF12906.7 KKK18062.1 - 5.3 7.2 14.8 4.4 7.5 12.3 2.2 1 1 1 2 2 2 0 RING-variant domain RecR PF02132.15 KKK18062.1 - 7.9 6.1 8.0 8.3 6.1 0.1 3.0 3 0 0 3 3 3 0 RecR protein Rhodanese PF00581.20 KKK18063.1 - 5.2e-15 55.9 0.0 2.8e-07 31.0 0.0 2.2 2 0 0 2 2 2 2 Rhodanese-like domain RPEL PF02755.15 KKK18064.1 - 3.1e-19 68.0 11.4 2.7e-10 39.6 2.4 2.5 2 0 0 2 2 2 2 RPEL repeat Myc_N PF01056.18 KKK18064.1 - 0.031 14.2 3.6 0.039 13.9 3.6 1.2 1 0 0 1 1 1 0 Myc amino-terminal region PBP_sp32 PF07222.12 KKK18064.1 - 5 6.5 8.8 6.1 6.2 8.8 1.2 1 0 0 1 1 1 0 Proacrosin binding protein sp32 PIN_4 PF13638.6 KKK18065.1 - 0.00027 21.2 0.1 0.0053 17.0 0.1 2.5 2 1 0 2 2 2 1 PIN domain YL1 PF05764.13 KKK18065.1 - 0.21 11.7 6.6 0.059 13.5 3.4 1.6 2 0 0 2 2 2 0 YL1 nuclear protein Mannosidase_ig PF17786.1 KKK18066.1 - 2e-17 63.6 3.2 2.8e-17 63.1 0.6 2.5 3 0 0 3 3 3 1 Mannosidase Ig/CBM-like domain Glyco_hydro_2 PF00703.21 KKK18066.1 - 3.4e-12 47.0 0.1 1e-11 45.4 0.1 1.9 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.18 KKK18066.1 - 0.00015 21.7 0.1 0.00062 19.7 0.0 2.0 2 1 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.17 KKK18066.1 - 0.0024 17.0 0.3 0.012 14.7 0.3 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Translin PF01997.16 KKK18067.1 - 8.5e-71 238.2 0.0 9.9e-71 238.0 0.0 1.0 1 0 0 1 1 1 1 Translin family CDC48_2 PF02933.17 KKK18067.1 - 0.068 13.0 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Cell division protein 48 (CDC48), domain 2 IMS PF00817.20 KKK18068.1 - 1.5e-41 141.9 1.4 2.1e-41 141.4 0.5 1.8 2 0 0 2 2 2 1 impB/mucB/samB family IMS_C PF11799.8 KKK18068.1 - 3.3e-15 56.8 1.3 1.5e-13 51.4 0.2 3.1 4 0 0 4 4 4 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 KKK18068.1 - 3.7e-05 23.8 0.0 0.0001 22.4 0.0 1.8 1 0 0 1 1 1 1 IMS family HHH motif Sec34 PF04136.15 KKK18068.1 - 0.31 10.9 5.3 0.22 11.4 0.6 2.4 2 0 0 2 2 2 0 Sec34-like family NIBRIN_BRCT_II PF16508.5 KKK18069.1 - 9e-37 126.0 0.0 4.7e-36 123.7 0.0 2.3 2 0 0 2 2 2 1 Second BRCT domain on Nijmegen syndrome breakage protein FHA PF00498.26 KKK18069.1 - 2.8e-08 34.0 0.3 7e-08 32.7 0.3 1.7 1 0 0 1 1 1 1 FHA domain Rbsn PF11464.8 KKK18069.1 - 0.013 15.3 2.5 0.043 13.5 2.5 1.9 1 0 0 1 1 1 0 Rabenosyn Rab binding domain RTT107_BRCT_5 PF16770.5 KKK18069.1 - 0.072 13.0 0.0 0.19 11.6 0.0 1.7 1 0 0 1 1 1 0 Regulator of Ty1 transposition protein 107 BRCT domain Yop-YscD_cpl PF16697.5 KKK18069.1 - 0.085 13.2 0.1 1.2 9.5 0.1 2.5 1 1 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain GFA PF04828.14 KKK18070.1 - 1e-22 80.3 0.2 1.4e-22 79.8 0.2 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme F-box-like PF12937.7 KKK18073.1 - 0.0017 18.2 0.0 0.0072 16.2 0.0 2.2 1 1 0 1 1 1 1 F-box-like Mannosyl_trans PF05007.13 KKK18074.1 - 1.5e-72 244.6 8.9 2e-57 195.0 9.9 2.4 2 0 0 2 2 2 2 Mannosyltransferase (PIG-M) Fungal_trans PF04082.18 KKK18074.1 - 4.4e-19 68.5 0.5 4.4e-19 68.5 0.5 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain PIG-U PF06728.13 KKK18074.1 - 3e-10 39.7 4.3 1.1e-09 37.8 4.3 2.0 1 1 0 1 1 1 1 GPI transamidase subunit PIG-U Zn_clus PF00172.18 KKK18074.1 - 1.5e-05 25.0 12.9 2.7e-05 24.2 12.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pex14_N PF04695.13 KKK18075.1 - 0.054 14.2 0.3 0.084 13.5 0.3 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Aldedh PF00171.22 KKK18076.1 - 1.9e-166 554.1 2.6 9.7e-156 518.9 0.7 2.0 1 1 1 2 2 2 2 Aldehyde dehydrogenase family Allantoicase PF03561.15 KKK18077.1 - 2.2e-85 283.9 0.0 4e-42 143.6 0.0 2.1 2 0 0 2 2 2 2 Allantoicase repeat HATPase_c PF02518.26 KKK18078.1 - 1.8e-32 112.2 0.0 7.3e-32 110.2 0.0 2.1 2 0 0 2 2 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KKK18078.1 - 2e-21 76.2 0.4 3.4e-20 72.3 0.0 2.8 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 KKK18078.1 - 2.3e-19 69.2 0.0 7.8e-19 67.5 0.0 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF_2 PF13185.6 KKK18078.1 - 1.4e-13 51.4 0.0 1.7e-12 47.8 0.0 2.6 2 0 0 2 2 2 1 GAF domain AAA_16 PF13191.6 KKK18078.1 - 1.4e-13 51.6 0.0 7.2e-13 49.3 0.0 2.2 1 0 0 1 1 1 1 AAA ATPase domain GAF PF01590.26 KKK18078.1 - 5.7e-08 33.5 0.0 1.5e-07 32.1 0.0 1.8 1 0 0 1 1 1 1 GAF domain Pkinase PF00069.25 KKK18078.1 - 2.3e-06 27.2 0.0 2.8e-05 23.6 0.0 2.6 3 0 0 3 3 2 1 Protein kinase domain GAF_3 PF13492.6 KKK18078.1 - 6.1e-06 26.6 0.0 2.1e-05 24.9 0.0 1.9 1 0 0 1 1 1 1 GAF domain NB-ARC PF00931.22 KKK18078.1 - 0.00028 20.2 0.4 0.5 9.5 0.0 3.4 4 0 0 4 4 4 2 NB-ARC domain HATPase_c_3 PF13589.6 KKK18078.1 - 0.0036 17.1 0.0 0.0081 16.0 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF3369 PF11849.8 KKK18078.1 - 0.004 17.4 1.0 0.054 13.7 1.0 2.6 1 1 0 1 1 1 1 Domain of unknown function (DUF3369) TPR_1 PF00515.28 KKK18078.1 - 0.048 13.5 0.0 26 4.9 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat AAA_22 PF13401.6 KKK18078.1 - 0.058 13.7 0.0 24 5.2 0.0 3.1 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 KKK18078.1 - 0.069 13.1 0.0 0.21 11.4 0.0 1.8 1 0 0 1 1 1 0 RsgA GTPase TPR_8 PF13181.6 KKK18078.1 - 0.075 13.3 0.0 0.55 10.6 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat NACHT PF05729.12 KKK18078.1 - 0.096 12.6 0.0 1.2 9.0 0.0 2.5 2 0 0 2 2 2 0 NACHT domain TPR_MalT PF17874.1 KKK18078.1 - 0.12 11.8 7.2 1.6 8.0 0.7 3.2 4 0 0 4 4 4 0 MalT-like TPR region TPR_19 PF14559.6 KKK18078.1 - 0.16 12.5 0.7 7.2 7.2 0.0 3.2 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 KKK18078.1 - 0.52 10.6 11.0 2.1 8.7 0.1 5.1 5 1 0 5 5 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 KKK18078.1 - 1.6 9.8 10.9 1.2 10.2 0.0 5.2 5 1 1 6 6 4 0 Tetratricopeptide repeat TPR_9 PF13371.6 KKK18078.1 - 4 7.7 6.5 78 3.5 0.1 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat Cytochrome_CBB3 PF13442.6 KKK18079.1 - 0.11 12.9 0.0 0.14 12.5 0.0 1.3 1 0 0 1 1 1 0 Cytochrome C oxidase, cbb3-type, subunit III Sugar_tr PF00083.24 KKK18080.1 - 6.7e-17 61.5 10.1 8.2e-17 61.2 10.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKK18080.1 - 0.00042 19.4 11.3 0.00055 19.0 11.3 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily PhoLip_ATPase_C PF16212.5 KKK18090.1 - 7.3e-70 235.6 22.1 7.3e-70 235.6 22.1 2.2 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KKK18090.1 - 2.3e-24 84.9 1.9 2.9e-22 78.1 0.1 2.9 3 0 0 3 3 3 2 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 KKK18090.1 - 4.9e-14 53.1 1.1 2.4e-05 24.7 0.2 3.4 2 1 1 3 3 3 3 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 KKK18090.1 - 5.3e-11 42.4 0.0 5.3e-11 42.4 0.0 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase PF13246.6 KKK18090.1 - 3.3e-10 39.9 0.0 2.6e-09 37.1 0.0 2.4 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KKK18090.1 - 0.00092 19.0 0.0 0.0043 16.8 0.0 2.0 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase DUF4404 PF14357.6 KKK18090.1 - 0.15 12.7 0.1 3.2 8.4 0.2 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) DUF1453 PF07301.11 KKK18090.1 - 2.7 8.0 6.5 2.4 8.2 2.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1453) AMP-binding PF00501.28 KKK18091.1 - 7.1e-88 295.0 0.0 1.1e-87 294.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KKK18091.1 - 5.9e-06 27.2 0.2 2.3e-05 25.3 0.1 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain PBP_like PF12727.7 KKK18091.1 - 0.18 10.9 0.0 0.36 9.9 0.0 1.4 1 0 0 1 1 1 0 PBP superfamily domain Thioredoxin PF00085.20 KKK18093.1 - 4.3e-29 100.5 0.2 4.9e-29 100.4 0.2 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KKK18093.1 - 1e-06 29.2 0.5 1.3e-05 25.6 0.5 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KKK18093.1 - 6.2e-06 26.5 0.0 7.2e-05 23.0 0.0 2.0 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.6 KKK18093.1 - 3.1e-05 23.7 0.0 4e-05 23.4 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Redoxin PF08534.10 KKK18093.1 - 0.00013 21.7 0.4 0.013 15.2 0.3 2.0 1 1 1 2 2 2 2 Redoxin OST3_OST6 PF04756.13 KKK18093.1 - 0.0009 18.7 0.0 0.0011 18.4 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 KKK18093.1 - 0.0018 18.2 0.1 0.0025 17.7 0.1 1.3 1 1 0 1 1 1 1 AhpC/TSA family TraF PF13728.6 KKK18093.1 - 0.018 14.9 0.0 0.025 14.4 0.0 1.2 1 0 0 1 1 1 0 F plasmid transfer operon protein Glutaredoxin PF00462.24 KKK18093.1 - 0.027 14.7 0.1 0.039 14.2 0.1 1.4 1 0 0 1 1 1 0 Glutaredoxin Thioredoxin_7 PF13899.6 KKK18093.1 - 0.07 13.3 0.1 0.094 12.9 0.1 1.4 1 1 0 1 1 1 0 Thioredoxin-like Asp-B-Hydro_N PF05279.11 KKK18094.1 - 1.3 9.0 5.8 2.9 7.9 5.8 1.5 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Es2 PF09751.9 KKK18095.1 - 1.7e-121 407.0 6.3 3.6e-69 234.6 0.0 2.0 2 0 0 2 2 2 2 Nuclear protein Es2 Mid1 PF12929.7 KKK18096.1 - 8.3e-128 427.2 13.2 5.2e-127 424.6 13.2 1.8 1 1 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Fz PF01392.22 KKK18096.1 - 0.019 15.6 5.2 0.053 14.1 3.7 2.4 2 1 0 2 2 2 0 Fz domain Ras PF00071.22 KKK18103.1 - 1.4e-39 135.3 0.0 1.5e-38 131.9 0.0 2.0 1 1 0 1 1 1 1 Ras family Roc PF08477.13 KKK18103.1 - 5e-30 104.2 0.0 7.1e-30 103.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKK18103.1 - 5.4e-11 42.3 0.0 8.5e-11 41.6 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KKK18103.1 - 0.00021 21.4 0.0 0.00032 20.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KKK18103.1 - 0.002 18.5 0.0 0.003 18.0 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain SRPRB PF09439.10 KKK18103.1 - 0.0089 15.5 0.0 0.014 14.9 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 KKK18103.1 - 0.011 16.0 0.0 0.032 14.5 0.0 1.7 2 1 0 2 2 2 0 AAA domain Gtr1_RagA PF04670.12 KKK18103.1 - 0.018 14.4 0.0 0.024 14.0 0.0 1.1 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 KKK18103.1 - 0.045 13.5 0.0 0.28 10.9 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_7 PF12775.7 KKK18103.1 - 0.063 12.8 0.1 0.1 12.1 0.1 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_14 PF13173.6 KKK18103.1 - 0.065 13.3 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 KKK18103.1 - 0.073 12.8 0.2 12 5.6 0.1 2.7 2 1 1 3 3 3 0 Conserved hypothetical ATP binding protein AAA_24 PF13479.6 KKK18103.1 - 0.097 12.4 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KKK18103.1 - 0.1 12.5 0.0 0.2 11.5 0.0 1.6 2 0 0 2 2 2 0 RsgA GTPase AAA_28 PF13521.6 KKK18103.1 - 0.12 12.6 0.3 0.19 11.9 0.0 1.5 2 0 0 2 2 1 0 AAA domain AAA_5 PF07728.14 KKK18103.1 - 0.17 11.9 0.0 0.28 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NACHT PF05729.12 KKK18103.1 - 0.19 11.7 0.1 0.29 11.0 0.1 1.3 1 0 0 1 1 1 0 NACHT domain DUF3431 PF11913.8 KKK18104.1 - 4.1e-85 284.9 1.0 4.9e-85 284.7 1.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) Sec63 PF02889.16 KKK18105.1 - 1.9e-133 443.4 0.0 1.2e-81 273.7 0.1 2.3 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 KKK18105.1 - 1.1e-50 171.9 1.2 1.7e-25 89.8 0.8 3.2 4 0 0 4 4 4 2 DEAD/DEAH box helicase ResIII PF04851.15 KKK18105.1 - 1.1e-22 80.9 0.0 3.5e-11 43.4 0.0 2.5 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KKK18105.1 - 2.6e-17 63.1 0.0 9.2e-07 29.2 0.0 4.3 4 2 0 4 4 4 2 Helicase conserved C-terminal domain AAA_22 PF13401.6 KKK18105.1 - 9.8e-08 32.4 0.3 0.0018 18.6 0.0 3.6 2 1 0 2 2 2 2 AAA domain AAA_30 PF13604.6 KKK18105.1 - 2.8e-07 30.4 0.3 0.007 16.1 0.5 2.4 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 KKK18105.1 - 1.4e-05 25.4 0.6 0.0037 17.6 0.7 2.7 2 0 0 2 2 2 1 AAA domain Helicase_PWI PF18149.1 KKK18105.1 - 0.0066 16.6 0.1 0.018 15.2 0.1 1.7 1 0 0 1 1 1 1 N-terminal helicase PWI domain TniB PF05621.11 KKK18105.1 - 0.027 13.9 0.5 16 4.9 0.0 3.4 4 0 0 4 4 4 0 Bacterial TniB protein IstB_IS21 PF01695.17 KKK18105.1 - 0.091 12.5 0.4 8.4 6.1 0.0 3.5 4 0 0 4 4 4 0 IstB-like ATP binding protein MARVEL PF01284.23 KKK18107.1 - 4.3e-19 69.0 12.8 5.2e-19 68.7 12.8 1.1 1 0 0 1 1 1 1 Membrane-associating domain CTP_transf_1 PF01148.20 KKK18107.1 - 0.2 11.4 6.1 0.23 11.2 6.1 1.1 1 0 0 1 1 1 0 Cytidylyltransferase family YL1_C PF08265.11 KKK18108.1 - 4.4e-16 58.3 0.4 7.2e-16 57.6 0.4 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain Profilin PF00235.19 KKK18109.1 - 8.6e-35 119.8 0.1 1.2e-34 119.3 0.1 1.2 1 0 0 1 1 1 1 Profilin Actin PF00022.19 KKK18110.1 - 9.1e-52 176.0 0.0 5.8e-28 97.6 0.0 2.5 2 1 0 2 2 2 2 Actin Tubulin_2 PF13809.6 KKK18110.1 - 0.2 10.8 2.2 0.42 9.7 2.2 1.5 1 0 0 1 1 1 0 Tubulin like DASH_Dad4 PF08650.10 KKK18111.1 - 6.1e-31 106.2 8.2 7.5e-31 105.9 8.2 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad4 CD34_antigen PF06365.12 KKK18111.1 - 0.011 15.3 1.0 0.013 15.1 1.0 1.1 1 0 0 1 1 1 0 CD34/Podocalyxin family GM_CSF PF01109.17 KKK18111.1 - 0.071 13.3 0.4 0.092 12.9 0.4 1.2 1 0 0 1 1 1 0 Granulocyte-macrophage colony-stimulating factor HOK_GEF PF01848.16 KKK18111.1 - 0.099 12.1 0.1 0.15 11.5 0.1 1.3 1 0 0 1 1 1 0 Hok/gef family PhyH PF05721.13 KKK18112.1 - 3.5e-08 33.9 0.0 1.9e-06 28.3 0.0 2.7 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Het-C PF07217.11 KKK18113.1 - 2e-281 934.5 0.0 3.2e-281 933.8 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C TctA PF01970.16 KKK18113.1 - 0.051 12.3 0.0 0.085 11.6 0.0 1.3 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctA family IBN_N PF03810.19 KKK18114.1 - 6.3e-11 42.0 0.1 1.2e-08 34.8 0.0 4.0 2 1 1 3 3 3 1 Importin-beta N-terminal domain RIX1 PF08167.12 KKK18114.1 - 6.4e-06 26.0 5.2 3.4e-05 23.7 0.3 4.0 4 0 0 4 4 4 1 rRNA processing/ribosome biogenesis Xpo1 PF08389.12 KKK18114.1 - 0.00037 20.6 0.5 0.043 13.9 0.0 4.1 5 0 0 5 5 5 1 Exportin 1-like protein Proteasom_PSMB PF10508.9 KKK18114.1 - 0.00058 18.5 0.3 0.0029 16.2 0.0 2.3 3 0 0 3 3 3 1 Proteasome non-ATPase 26S subunit Cnd3 PF12719.7 KKK18114.1 - 0.0054 16.0 0.6 0.53 9.4 0.1 3.1 2 1 1 3 3 3 1 Nuclear condensing complex subunits, C-term domain CAS_CSE1 PF03378.15 KKK18114.1 - 0.016 13.7 0.0 0.043 12.3 0.0 1.7 1 0 0 1 1 1 0 CAS/CSE protein, C-terminus RICTOR_N PF14664.6 KKK18114.1 - 0.18 10.8 2.6 0.19 10.7 1.1 1.8 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR, N-term HEAT_EZ PF13513.6 KKK18114.1 - 0.25 11.9 10.8 3.1 8.4 0.3 5.3 5 0 0 5 5 5 0 HEAT-like repeat Methyltransf_23 PF13489.6 KKK18115.1 - 1.8e-24 86.4 0.0 2.5e-24 86.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKK18115.1 - 1.1e-11 45.3 0.0 2.9e-11 43.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KKK18115.1 - 1.2e-10 42.0 0.0 4.5e-10 40.2 0.0 1.9 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KKK18115.1 - 2.4e-09 37.1 0.0 1.2e-08 34.9 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KKK18115.1 - 7.2e-09 36.2 0.0 1.4e-08 35.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 KKK18115.1 - 0.0034 17.1 0.0 0.0057 16.4 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase CMAS PF02353.20 KKK18115.1 - 0.0034 16.7 0.0 0.0089 15.3 0.0 1.7 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_4 PF02390.17 KKK18115.1 - 0.0054 16.2 0.0 0.02 14.3 0.0 1.8 2 0 0 2 2 2 1 Putative methyltransferase MTS PF05175.14 KKK18115.1 - 0.007 15.9 0.0 0.03 13.9 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase small domain PrmA PF06325.13 KKK18115.1 - 0.016 14.6 0.0 0.023 14.1 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_2 PF00891.18 KKK18115.1 - 0.042 13.1 0.0 0.07 12.4 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase domain DUF938 PF06080.12 KKK18115.1 - 0.1 12.3 0.0 0.46 10.2 0.0 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF938) DUF5600 PF18150.1 KKK18115.1 - 0.16 12.5 0.0 0.46 11.1 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5600) HORMA PF02301.18 KKK18116.1 - 3.9e-10 39.7 0.0 5.1e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 HORMA domain Fungal_trans PF04082.18 KKK18117.1 - 8.5e-39 133.2 0.0 1.3e-38 132.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain NYAP_C PF15452.6 KKK18117.1 - 0.029 14.2 1.0 0.11 12.4 0.1 2.2 2 0 0 2 2 2 0 Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter Fungal_trans_2 PF11951.8 KKK18117.1 - 0.043 12.6 0.0 0.068 12.0 0.0 1.2 1 0 0 1 1 1 0 Fungal specific transcription factor domain MRI PF15325.6 KKK18117.1 - 3.4 8.8 7.0 43 5.3 3.5 2.8 2 0 0 2 2 2 0 Modulator of retrovirus infection Glyco_hydro_18 PF00704.28 KKK18118.1 - 1.1e-43 150.2 0.9 1.4e-43 149.8 0.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 LysM PF01476.20 KKK18118.1 - 1.6e-08 34.4 0.0 0.00012 22.1 0.0 2.7 2 0 0 2 2 2 2 LysM domain Chitin_bind_1 PF00187.19 KKK18118.1 - 0.00019 21.8 7.2 0.00019 21.8 7.2 4.1 5 0 0 5 5 5 1 Chitin recognition protein DUF92 PF01940.16 KKK18119.1 - 3e-83 278.9 11.0 3.6e-83 278.6 11.0 1.1 1 0 0 1 1 1 1 Integral membrane protein DUF92 Peptidase_A8 PF01252.18 KKK18119.1 - 0.056 13.7 1.9 0.28 11.4 0.2 2.3 1 1 0 2 2 2 0 Signal peptidase (SPase) II Amidohydro_1 PF01979.20 KKK18120.1 - 6e-32 111.3 0.0 8.9e-32 110.7 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KKK18120.1 - 1.5e-13 51.0 0.2 2.5e-08 33.9 0.0 2.7 3 0 0 3 3 3 2 Amidohydrolase family Methyltransf_33 PF10017.9 KKK18121.1 - 8.6e-82 274.7 0.0 1.2e-81 274.3 0.0 1.1 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent FGE-sulfatase PF03781.16 KKK18121.1 - 6e-22 78.5 1.8 5e-20 72.2 1.8 2.3 1 1 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.7 KKK18121.1 - 2e-07 31.6 0.0 2.6e-06 28.0 0.0 2.5 2 0 0 2 2 2 1 DinB superfamily Xpo1 PF08389.12 KKK18123.1 - 1e-43 148.9 0.1 5.7e-43 146.5 0.0 2.4 2 0 0 2 2 2 1 Exportin 1-like protein MFS_1 PF07690.16 KKK18123.1 - 7.2e-31 107.4 49.5 6e-26 91.2 32.8 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily HEAT PF02985.22 KKK18123.1 - 0.0008 19.5 0.2 2.2 8.8 0.0 4.6 5 0 0 5 5 5 1 HEAT repeat Tom22 PF04281.13 KKK18123.1 - 0.13 12.0 1.2 4.1 7.2 0.1 2.6 2 0 0 2 2 2 0 Mitochondrial import receptor subunit Tom22 CelTOS PF18659.1 KKK18123.1 - 0.47 10.9 1.5 3.5 8.1 0.2 3.2 3 1 0 3 3 3 0 Cell-traversal protein for ookinetes and sporozoites PAP2_3 PF14378.6 KKK18124.1 - 4.9e-41 140.5 13.1 4.9e-41 140.5 13.1 1.7 3 0 0 3 3 3 1 PAP2 superfamily PAP2 PF01569.21 KKK18124.1 - 0.0082 15.9 11.3 0.038 13.7 11.3 2.2 1 1 0 1 1 1 1 PAP2 superfamily PAP2_C PF14360.6 KKK18124.1 - 0.013 16.0 2.1 0.013 16.0 2.1 2.7 3 0 0 3 3 3 0 PAP2 superfamily C-terminal FGGY_C PF02782.16 KKK18125.1 - 1.6e-30 106.3 0.0 2.2e-30 105.9 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 KKK18125.1 - 7.8e-08 32.2 0.0 1.2e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain HAD_2 PF13419.6 KKK18128.1 - 4.3e-13 49.7 0.0 5.5e-13 49.4 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KKK18128.1 - 7.7e-07 29.6 0.0 1.4e-06 28.8 0.0 1.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KKK18128.1 - 0.00016 21.7 0.0 0.00025 21.0 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like DBD_Tnp_Hermes PF10683.9 KKK18128.1 - 0.16 11.7 0.1 0.35 10.6 0.0 1.6 1 1 0 1 1 1 0 Hermes transposase DNA-binding domain Fungal_trans_2 PF11951.8 KKK18132.1 - 4.2e-65 220.0 0.0 4.8e-65 219.8 0.0 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain V-ATPase_C PF03223.15 KKK18134.1 - 6.3e-84 282.5 0.1 7.1e-84 282.3 0.1 1.0 1 0 0 1 1 1 1 V-ATPase subunit C Phospho_p8 PF10195.9 KKK18134.1 - 0.53 10.8 3.3 6.4 7.4 0.7 2.7 2 0 0 2 2 2 0 DNA-binding nuclear phosphoprotein p8 zf_Hakai PF18408.1 KKK18136.1 - 0.1 12.3 0.1 0.2 11.4 0.1 1.4 1 0 0 1 1 1 0 C2H2 Hakai zinc finger domain Tropomyosin_1 PF12718.7 KKK18137.1 - 2e-54 183.6 34.7 2.3e-54 183.4 34.7 1.0 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.20 KKK18137.1 - 2.9e-09 36.6 33.3 0.00041 19.8 13.1 2.8 1 1 1 2 2 2 2 Tropomyosin KLRAQ PF10205.9 KKK18137.1 - 7e-05 23.0 12.7 7e-05 23.0 12.7 2.8 1 1 1 2 2 2 1 Predicted coiled-coil domain-containing protein BST2 PF16716.5 KKK18137.1 - 0.00025 21.6 27.7 0.0023 18.4 6.1 3.7 1 1 3 4 4 4 1 Bone marrow stromal antigen 2 Spc7 PF08317.11 KKK18137.1 - 0.0017 17.3 32.2 0.11 11.3 13.2 2.0 1 1 1 2 2 2 2 Spc7 kinetochore protein Uso1_p115_C PF04871.13 KKK18137.1 - 0.004 17.5 35.8 0.25 11.7 15.5 2.1 1 1 1 2 2 2 2 Uso1 / p115 like vesicle tethering protein, C terminal region FlaC_arch PF05377.11 KKK18137.1 - 0.0051 17.2 18.8 0.11 13.0 1.6 4.3 1 1 3 4 4 4 1 Flagella accessory protein C (FlaC) ERM PF00769.19 KKK18137.1 - 0.0056 16.5 36.9 0.033 14.0 15.9 2.1 1 1 1 2 2 2 1 Ezrin/radixin/moesin family bZIP_1 PF00170.21 KKK18137.1 - 0.0067 16.5 27.6 1.2 9.3 1.7 4.6 2 1 3 5 5 5 3 bZIP transcription factor SOGA PF11365.8 KKK18137.1 - 0.012 16.7 24.4 0.94 10.6 9.4 3.1 2 1 1 3 3 3 0 Protein SOGA DUF724 PF05266.14 KKK18137.1 - 0.012 15.4 24.5 0.015 15.2 8.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) ATG16 PF08614.11 KKK18137.1 - 0.026 14.8 32.5 3.3 7.9 18.8 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) GAS PF13851.6 KKK18137.1 - 0.03 13.7 30.9 0.23 10.8 4.1 2.4 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Fez1 PF06818.15 KKK18137.1 - 0.037 14.5 26.1 0.057 13.9 26.1 1.3 1 0 0 1 1 1 0 Fez1 Cast PF10174.9 KKK18137.1 - 0.047 11.9 24.8 0.08 11.2 24.8 1.4 1 1 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone Laminin_II PF06009.12 KKK18137.1 - 0.056 13.5 18.3 0.047 13.7 6.7 2.3 1 1 1 2 2 2 0 Laminin Domain II CASP_C PF08172.12 KKK18137.1 - 0.056 12.8 0.9 0.056 12.8 0.9 2.1 1 1 1 2 2 2 0 CASP C terminal KASH_CCD PF14662.6 KKK18137.1 - 0.061 13.1 30.9 0.43 10.4 19.6 3.0 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH Jnk-SapK_ap_N PF09744.9 KKK18137.1 - 0.065 13.5 32.7 0.33 11.2 24.9 2.2 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 APG6_N PF17675.1 KKK18137.1 - 0.073 13.6 40.4 0.022 15.3 24.0 2.0 1 1 1 2 2 2 0 Apg6 coiled-coil region MAD PF05557.13 KKK18137.1 - 0.079 11.3 29.7 0.098 11.0 29.7 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein WXG100 PF06013.12 KKK18137.1 - 0.079 13.2 15.5 3.2 8.1 0.1 3.4 2 1 1 3 3 3 0 Proteins of 100 residues with WXG ADIP PF11559.8 KKK18137.1 - 0.08 13.0 29.1 2.7 8.0 4.9 3.3 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding TACC_C PF05010.14 KKK18137.1 - 0.092 12.5 26.9 0.59 9.9 2.1 2.8 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal DUF4482 PF14818.6 KKK18137.1 - 0.095 13.6 1.8 0.095 13.6 1.8 3.0 1 1 0 2 2 2 0 Domain of unknown function (DUF4482) DUF3450 PF11932.8 KKK18137.1 - 0.1 11.9 28.6 1.1 8.5 15.7 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) TMF_TATA_bd PF12325.8 KKK18137.1 - 0.15 12.3 27.6 0.26 11.5 15.0 2.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Taxilin PF09728.9 KKK18137.1 - 0.16 11.1 29.3 0.12 11.5 8.2 2.3 1 1 1 2 2 2 0 Myosin-like coiled-coil protein DUF4200 PF13863.6 KKK18137.1 - 0.19 12.1 33.7 0.15 12.5 15.1 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) TMF_DNA_bd PF12329.8 KKK18137.1 - 0.2 11.7 36.3 0.052 13.5 15.0 3.5 1 1 1 2 2 1 0 TATA element modulatory factor 1 DNA binding EzrA PF06160.12 KKK18137.1 - 0.21 9.7 23.2 0.36 9.0 7.9 2.1 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA DUF1664 PF07889.12 KKK18137.1 - 0.22 11.5 14.3 2.5 8.2 6.0 2.7 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) ZapB PF06005.12 KKK18137.1 - 0.24 11.9 36.9 0.27 11.7 5.4 4.2 1 1 3 4 4 4 0 Cell division protein ZapB FAM76 PF16046.5 KKK18137.1 - 0.32 10.3 21.9 2.7 7.3 8.3 2.1 1 1 1 2 2 2 0 FAM76 protein KELK PF15796.5 KKK18137.1 - 0.33 11.4 32.8 4.8 7.7 13.5 4.1 1 1 2 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF812 PF05667.11 KKK18137.1 - 0.34 9.7 29.6 0.43 9.4 29.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Leu_zip PF15294.6 KKK18137.1 - 0.35 10.3 21.8 0.44 10.0 21.8 1.1 1 0 0 1 1 1 0 Leucine zipper DUF5082 PF16888.5 KKK18137.1 - 0.37 11.1 24.2 21 5.4 17.0 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) TPR_MLP1_2 PF07926.12 KKK18137.1 - 0.44 10.6 37.1 0.31 11.1 11.3 3.0 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein SlyX PF04102.12 KKK18137.1 - 0.62 10.7 24.0 0.35 11.5 5.2 3.6 1 1 3 4 4 4 0 SlyX Qua1 PF16274.5 KKK18137.1 - 0.65 9.9 0.1 0.65 9.9 0.1 3.0 3 1 1 4 4 2 0 Qua1 domain Sipho_Gp157 PF05565.11 KKK18137.1 - 0.79 9.7 24.0 0.2 11.7 8.2 2.4 1 1 0 2 2 2 0 Siphovirus Gp157 Syntaxin-6_N PF09177.11 KKK18137.1 - 0.84 10.2 20.2 0.99 10.0 2.2 2.9 1 1 2 3 3 3 0 Syntaxin 6, N-terminal Dynamitin PF04912.14 KKK18137.1 - 0.91 8.8 27.1 52 3.0 27.1 2.7 1 1 0 1 1 1 0 Dynamitin Fmp27_WPPW PF10359.9 KKK18137.1 - 1 8.1 24.0 0.21 10.4 9.2 2.1 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain XhlA PF10779.9 KKK18137.1 - 1.1 9.6 24.7 2.5 8.4 2.1 4.1 1 1 4 5 5 5 0 Haemolysin XhlA DUF4201 PF13870.6 KKK18137.1 - 1.2 8.8 25.6 5.4 6.7 23.0 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) CLZ PF16526.5 KKK18137.1 - 1.3 9.4 26.0 15 6.0 3.2 3.7 1 1 3 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Ctf8 PF09696.10 KKK18137.1 - 1.5 9.1 8.8 2.4 8.5 7.2 2.1 1 1 0 1 1 1 0 Ctf8 DUF4600 PF15372.6 KKK18137.1 - 1.6 9.1 22.7 1.1 9.7 7.8 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4600) TMPIT PF07851.13 KKK18137.1 - 1.8 7.8 20.9 0.92 8.7 2.5 2.0 1 1 1 2 2 2 0 TMPIT-like protein Seryl_tRNA_N PF02403.22 KKK18137.1 - 1.8 8.8 27.6 3.8 7.8 11.6 3.1 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Atg14 PF10186.9 KKK18137.1 - 1.9 7.5 23.6 0.28 10.2 9.5 2.0 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Lge1 PF11488.8 KKK18137.1 - 2 8.7 22.6 1.7 8.8 1.1 4.0 1 1 3 4 4 4 0 Transcriptional regulatory protein LGE1 YabA PF06156.13 KKK18137.1 - 2.2 9.0 23.0 3.8 8.2 11.4 3.3 1 1 2 3 3 3 0 Initiation control protein YabA Lectin_N PF03954.14 KKK18137.1 - 2.3 7.9 16.5 4.8 6.9 3.0 3.2 1 1 2 3 3 3 0 Hepatic lectin, N-terminal domain FapA PF03961.13 KKK18137.1 - 2.4 6.6 25.0 0.45 9.1 8.0 2.0 1 1 1 2 2 2 0 Flagellar Assembly Protein A AAA_13 PF13166.6 KKK18137.1 - 2.6 6.6 23.0 2.5 6.6 8.3 1.9 1 1 1 2 2 2 0 AAA domain DUF745 PF05335.13 KKK18137.1 - 2.6 7.7 21.1 3.3 7.4 4.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF745) PspA_IM30 PF04012.12 KKK18137.1 - 2.8 7.5 31.2 8.1 5.9 9.2 3.1 1 1 1 2 2 2 0 PspA/IM30 family CALCOCO1 PF07888.11 KKK18137.1 - 2.9 6.6 32.5 0.73 8.6 9.5 2.2 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like CENP-F_leu_zip PF10473.9 KKK18137.1 - 3.1 7.8 32.9 12 5.9 16.4 2.5 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CENP-H PF05837.12 KKK18137.1 - 3.1 8.2 26.3 3 8.3 0.2 3.0 1 1 2 3 3 3 0 Centromere protein H (CENP-H) DUF4407 PF14362.6 KKK18137.1 - 3.7 6.8 23.9 71 2.6 23.9 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DivIC PF04977.15 KKK18137.1 - 3.7 7.4 31.8 0.05 13.4 3.5 4.4 1 1 3 4 4 4 0 Septum formation initiator DUF3584 PF12128.8 KKK18137.1 - 3.8 4.9 28.1 7.9 3.8 28.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) MbeD_MobD PF04899.12 KKK18137.1 - 4.1 7.6 14.0 1.3 9.2 2.3 3.3 1 1 2 4 4 4 0 MbeD/MobD like DUF2203 PF09969.9 KKK18137.1 - 4.4 8.0 19.9 15 6.3 5.9 2.7 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) FUSC PF04632.12 KKK18137.1 - 4.6 5.7 9.9 5 5.5 9.9 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family IFT46_B_C PF12317.8 KKK18137.1 - 5.7 6.6 10.3 0.74 9.5 5.4 1.8 1 1 1 2 2 2 0 Intraflagellar transport complex B protein 46 C terminal Rx_N PF18052.1 KKK18137.1 - 5.8 7.3 15.9 1 9.7 8.0 2.6 1 1 2 3 3 3 0 Rx N-terminal domain HAUS-augmin3 PF14932.6 KKK18137.1 - 6.3 6.3 28.4 2.2 7.8 11.2 2.2 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 Striatin PF08232.12 KKK18137.1 - 7 7.2 26.2 2.7 8.6 1.7 2.1 1 1 1 2 2 2 0 Striatin family BRE1 PF08647.11 KKK18137.1 - 7.4 6.7 30.6 7.3 6.7 17.7 2.4 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase DUF5595 PF18077.1 KKK18137.1 - 7.6 6.7 19.2 0.71 10.0 4.0 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF5595) Phage_GPO PF05929.11 KKK18137.1 - 9.8 5.7 21.0 5.7 6.5 16.1 2.0 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Fungal_trans_2 PF11951.8 KKK18138.1 - 2e-26 92.7 0.0 6.3e-26 91.1 0.0 1.6 1 1 1 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK18138.1 - 1.6e-07 31.3 8.2 1.6e-07 31.3 8.2 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cu_amine_oxid PF01179.20 KKK18139.1 - 2.2e-164 547.2 1.1 2.7e-164 547.0 1.1 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.16 KKK18139.1 - 2.8e-05 24.2 0.0 5.3e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Cu_amine_oxidN3 PF02728.16 KKK18139.1 - 0.015 15.7 0.0 0.033 14.6 0.0 1.5 1 0 0 1 1 1 0 Copper amine oxidase, N3 domain CMAS PF02353.20 KKK18140.1 - 1.3e-62 211.6 0.1 1.7e-62 211.2 0.1 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 KKK18140.1 - 1e-08 35.8 0.0 2.2e-08 34.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KKK18140.1 - 2.7e-08 33.8 0.0 4.5e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KKK18140.1 - 1.1e-07 32.4 0.0 2.1e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KKK18140.1 - 0.00099 19.8 0.0 0.0019 18.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.13 KKK18140.1 - 0.011 15.3 0.0 0.021 14.4 0.0 1.4 1 0 0 1 1 1 0 Histone methylation protein DOT1 MTS PF05175.14 KKK18140.1 - 0.024 14.2 0.0 0.039 13.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain N6_N4_Mtase PF01555.18 KKK18140.1 - 0.065 12.9 0.0 8.2 6.1 0.0 2.4 2 0 0 2 2 2 0 DNA methylase FtsJ PF01728.19 KKK18140.1 - 0.17 12.0 0.0 0.27 11.3 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase PCMT PF01135.19 KKK18140.1 - 0.17 11.6 0.0 0.26 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 KKK18140.1 - 0.2 11.4 0.0 0.41 10.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Mucin PF01456.17 KKK18141.1 - 9.6e-06 25.6 27.2 9.6e-06 25.6 27.2 1.7 2 0 0 2 2 2 1 Mucin-like glycoprotein Dicty_REP PF05086.12 KKK18141.1 - 0.011 13.8 4.6 0.013 13.5 4.6 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein TrkH PF02386.16 KKK18141.1 - 0.038 12.4 4.6 0.054 11.9 4.6 1.1 1 0 0 1 1 1 0 Cation transport protein DUF3357 PF11837.8 KKK18141.1 - 0.065 13.7 6.4 0.17 12.4 3.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) SpoIIIAH PF12685.7 KKK18141.1 - 1.9 8.3 11.8 2.6 7.8 11.8 1.5 1 1 0 1 1 1 0 SpoIIIAH-like protein DUF4834 PF16118.5 KKK18141.1 - 1.9 9.5 7.1 1.1 10.3 1.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) PI3K_1B_p101 PF10486.9 KKK18141.1 - 2.6 5.7 8.6 3.8 5.2 8.6 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Pex14_N PF04695.13 KKK18141.1 - 5.1 7.7 24.5 0.056 14.1 9.4 2.6 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region ATP-synt_S1 PF05827.12 KKK18142.1 - 0.0024 17.7 0.0 0.0041 17.0 0.0 1.4 1 0 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) Nuc_recep-AF1 PF11825.8 KKK18142.1 - 0.011 15.8 0.1 0.019 15.0 0.1 1.4 1 0 0 1 1 1 0 Nuclear/hormone receptor activator site AF-1 Nop25 PF09805.9 KKK18143.1 - 4.6e-36 124.3 19.4 4.6e-36 124.3 19.4 3.0 2 1 1 3 3 3 1 Nucleolar protein 12 (25kDa) Herpes_DNAp_acc PF04929.12 KKK18143.1 - 0.75 8.7 15.2 1 8.2 15.2 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor MBOAT PF03062.19 KKK18144.1 - 1.1e-27 97.4 11.9 1.6e-27 96.8 11.9 1.1 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 KKK18144.1 - 0.64 10.3 5.4 0.51 10.6 2.9 2.1 2 0 0 2 2 2 0 Membrane bound O-acyl transferase family Tmemb_170 PF10190.9 KKK18145.1 - 1.4e-23 83.3 8.2 1.6e-23 83.1 8.2 1.0 1 0 0 1 1 1 1 Putative transmembrane protein 170 WD40 PF00400.32 KKK18146.1 - 1.1e-33 114.6 33.2 1.5e-06 28.8 3.9 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKK18146.1 - 2.6e-17 62.9 0.2 8.3e-05 22.8 0.0 5.7 2 1 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KKK18146.1 - 0.00069 19.6 0.1 0.31 10.9 0.1 2.6 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Frtz PF11768.8 KKK18146.1 - 0.023 13.0 0.0 0.17 10.2 0.0 1.9 1 1 2 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz DEC-1_N PF04625.13 KKK18146.1 - 4.3 6.2 9.7 7.1 5.5 9.7 1.3 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region OMPdecase PF00215.24 KKK18147.1 - 1.8e-77 260.0 0.0 2.5e-77 259.5 0.0 1.2 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family MAPEG PF01124.18 KKK18147.1 - 9e-24 83.8 0.2 1.6e-23 83.1 0.2 1.4 1 0 0 1 1 1 1 MAPEG family ICMT PF04140.14 KKK18148.1 - 3.8e-05 24.0 1.5 4.2e-05 23.9 0.1 1.8 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family DUF1039 PF06287.11 KKK18150.1 - 0.034 14.5 0.0 0.067 13.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1039) PEX11 PF05648.14 KKK18151.1 - 1.4e-08 34.5 0.2 9e-07 28.6 0.2 2.1 1 1 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Cullin_binding PF03556.15 KKK18152.1 - 7.1e-31 107.1 0.4 7.1e-31 107.1 0.4 1.9 2 0 0 2 2 2 1 Cullin binding UBA_4 PF14555.6 KKK18152.1 - 4.7e-13 48.7 0.6 1.4e-12 47.2 0.4 1.9 2 0 0 2 2 2 1 UBA-like domain TAP_C PF03943.13 KKK18152.1 - 0.024 14.3 0.0 0.048 13.3 0.0 1.5 1 0 0 1 1 1 0 TAP C-terminal domain CRAL_TRIO_N PF03765.15 KKK18152.1 - 0.026 14.7 0.0 0.062 13.5 0.0 1.6 1 0 0 1 1 1 0 CRAL/TRIO, N-terminal domain NOC3p PF07540.11 KKK18153.1 - 6.4e-31 106.7 0.2 2.4e-30 104.8 0.2 2.1 1 0 0 1 1 1 1 Nucleolar complex-associated protein CBF PF03914.17 KKK18153.1 - 8.1e-27 94.3 0.1 8.1e-27 94.3 0.1 2.5 3 0 0 3 3 3 1 CBF/Mak21 family DUF2570 PF10828.8 KKK18153.1 - 0.3 10.9 3.1 0.8 9.5 3.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) Cwf_Cwc_15 PF04889.12 KKK18153.1 - 2.1 8.0 30.1 5.4 6.7 16.5 2.5 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Sigma70_ner PF04546.13 KKK18153.1 - 5.5 6.8 23.2 0.25 11.2 8.2 3.3 3 0 0 3 3 3 0 Sigma-70, non-essential region PRC2_HTH_1 PF18118.1 KKK18153.1 - 9.5 7.1 13.2 0.61 10.9 0.2 3.5 3 0 0 3 3 3 0 Polycomb repressive complex 2 tri-helical domain NMD3 PF04981.13 KKK18154.1 - 4.9 6.5 6.0 2.7 7.4 0.8 2.1 2 0 0 2 2 2 0 NMD3 family Mpv17_PMP22 PF04117.12 KKK18155.1 - 2.3e-12 46.9 1.6 4.7e-11 42.7 0.8 2.3 2 0 0 2 2 2 2 Mpv17 / PMP22 family Noelin-1 PF12308.8 KKK18156.1 - 0.044 13.8 1.7 0.11 12.5 1.7 1.7 1 0 0 1 1 1 0 Neurogenesis glycoprotein CDC48_N PF02359.18 KKK18157.1 - 3.9e-19 68.6 0.7 5.2e-19 68.2 0.4 1.4 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), N-terminal domain eIF-1a PF01176.19 KKK18157.1 - 0.19 11.6 1.1 1.4 8.8 0.3 2.1 1 1 1 2 2 2 0 Translation initiation factor 1A / IF-1 2-Hacid_dh_C PF02826.19 KKK18184.1 - 1.3e-20 73.5 0.1 1.6e-20 73.2 0.1 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Zn_clus PF00172.18 KKK18185.1 - 1.5e-08 34.6 8.6 2.3e-08 34.0 8.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PUA PF01472.20 KKK18186.1 - 2.6e-15 56.2 0.1 3.6e-15 55.7 0.1 1.2 1 0 0 1 1 1 1 PUA domain Pre-PUA PF17832.1 KKK18186.1 - 2.8e-05 24.7 0.5 4.2e-05 24.1 0.5 1.3 1 0 0 1 1 1 1 Pre-PUA-like domain Mito_carr PF00153.27 KKK18187.1 - 3.7e-60 199.9 4.8 1.2e-18 66.8 0.0 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein TPK_catalytic PF04263.16 KKK18189.1 - 1.3e-31 109.1 0.0 1.9e-31 108.6 0.0 1.2 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.14 KKK18189.1 - 2.6e-11 43.1 0.2 4.3e-11 42.4 0.2 1.3 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain Septin PF00735.18 KKK18190.1 - 2.2e-121 404.5 0.1 2.2e-121 404.5 0.1 1.6 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 KKK18190.1 - 1.9e-08 34.4 0.0 4.9e-08 33.0 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KKK18190.1 - 1.8e-05 24.4 1.2 0.0018 17.9 0.0 2.8 2 2 0 2 2 2 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 KKK18190.1 - 0.00016 22.2 2.5 0.023 15.2 0.0 2.9 2 1 0 3 3 3 1 ABC transporter RsgA_GTPase PF03193.16 KKK18190.1 - 0.00019 21.4 3.3 0.0022 17.9 0.9 3.1 2 1 0 2 2 2 1 RsgA GTPase AIG1 PF04548.16 KKK18190.1 - 0.0011 18.3 1.6 0.0026 17.1 0.0 2.2 2 0 0 2 2 2 1 AIG1 family AAA_16 PF13191.6 KKK18190.1 - 0.0018 18.7 0.1 0.0057 17.0 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain Roc PF08477.13 KKK18190.1 - 0.0026 18.0 0.0 0.0054 16.9 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_22 PF13401.6 KKK18190.1 - 0.0047 17.2 0.6 0.019 15.2 0.0 2.3 2 2 0 2 2 2 1 AAA domain Ras PF00071.22 KKK18190.1 - 0.0055 16.3 0.1 0.036 13.7 0.0 2.3 2 0 0 2 2 2 1 Ras family AAA_29 PF13555.6 KKK18190.1 - 0.015 15.0 0.0 0.029 14.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Dynamin_N PF00350.23 KKK18190.1 - 0.031 14.4 5.8 0.94 9.5 0.0 3.7 4 1 0 4 4 3 0 Dynamin family AAA_24 PF13479.6 KKK18190.1 - 0.05 13.3 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 KKK18190.1 - 0.066 12.6 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family RNA_helicase PF00910.22 KKK18190.1 - 0.067 13.6 0.8 0.85 10.0 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA_7 PF12775.7 KKK18190.1 - 0.11 12.0 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Exonuc_VII_L PF02601.15 KKK18190.1 - 0.14 11.7 4.8 0.24 10.9 4.8 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit ATP_bind_1 PF03029.17 KKK18190.1 - 0.29 10.9 5.3 1.8 8.3 0.0 3.1 3 1 0 3 3 3 0 Conserved hypothetical ATP binding protein TSNAXIP1_N PF15739.5 KKK18190.1 - 3 8.3 14.2 3.2 8.2 0.0 2.8 2 1 1 3 3 2 0 Translin-associated factor X-interacting N-terminus DUF3987 PF13148.6 KKK18190.1 - 9 5.2 9.4 2.1 7.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) UPF0121 PF03661.13 KKK18191.1 - 5.6e-23 81.6 7.6 3.2e-19 69.3 1.2 2.0 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0121) An_peroxidase PF03098.15 KKK18193.1 - 1.9e-37 129.1 0.0 2.5e-24 85.7 0.0 3.2 1 1 1 2 2 2 2 Animal haem peroxidase DUF2235 PF09994.9 KKK18194.1 - 3.1e-101 338.5 0.2 4.2e-101 338.1 0.2 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Amino_oxidase PF01593.24 KKK18196.1 - 1.6e-41 143.1 4.0 9.8e-18 64.7 0.0 3.0 2 1 0 3 3 3 3 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KKK18196.1 - 1.9e-14 53.6 0.5 4.3e-14 52.5 0.5 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KKK18196.1 - 8e-07 29.2 0.2 0.0023 18.0 0.3 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox PF00070.27 KKK18196.1 - 2.4e-06 28.0 0.1 4.6e-06 27.1 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KKK18196.1 - 6.5e-06 25.6 1.2 1.5e-05 24.4 1.2 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KKK18196.1 - 3.9e-05 22.5 0.2 3.9e-05 22.5 0.2 1.5 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.24 KKK18196.1 - 0.00011 21.9 2.3 0.00086 19.0 2.3 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 KKK18196.1 - 0.00034 20.0 0.1 0.00054 19.3 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 KKK18196.1 - 0.00049 19.3 1.0 0.00072 18.8 1.0 1.2 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 KKK18196.1 - 0.0027 17.0 0.1 0.0048 16.2 0.1 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.19 KKK18196.1 - 0.0034 16.7 0.1 0.0051 16.1 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 KKK18196.1 - 0.0045 16.1 0.5 0.007 15.5 0.5 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 KKK18196.1 - 0.0074 15.7 0.9 0.011 15.1 0.9 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase 3HCDH_N PF02737.18 KKK18196.1 - 0.028 14.3 0.7 0.042 13.7 0.2 1.5 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 KKK18196.1 - 0.19 12.2 0.1 0.38 11.2 0.1 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding FMO-like PF00743.19 KKK18196.1 - 0.21 10.0 0.0 0.35 9.2 0.0 1.3 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KKK18196.1 - 0.48 9.6 1.8 0.55 9.4 0.3 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Dickkopf_N PF04706.12 KKK18197.1 - 0.00028 21.3 33.2 0.062 13.8 1.9 4.5 4 1 0 4 4 4 3 Dickkopf N-terminal cysteine-rich region DUF1582 PF07621.11 KKK18197.1 - 0.0025 17.7 3.6 1.2 9.1 0.2 3.4 3 0 0 3 3 3 2 Protein of unknown function (DUF1582) Nodulin_late PF07127.11 KKK18197.1 - 0.016 15.5 1.7 0.016 15.5 1.7 5.0 5 0 0 5 5 5 0 Late nodulin protein Toxin_23 PF08093.11 KKK18197.1 - 0.057 13.6 28.5 0.12 12.5 1.2 4.2 4 1 0 4 4 4 0 Magi 5 toxic peptide family WAP PF00095.21 KKK18197.1 - 1.8 9.1 39.7 4.8 7.7 1.4 4.3 2 1 2 4 4 4 0 WAP-type (Whey Acidic Protein) 'four-disulfide core' Antifungal_pept PF11410.8 KKK18197.1 - 5.3 7.0 21.1 11 6.1 1.2 4.2 4 0 0 4 4 4 0 Antifungal peptide EamA PF00892.20 KKK18198.1 - 5.9e-07 29.7 12.5 5.9e-07 29.7 12.5 2.2 2 0 0 2 2 2 1 EamA-like transporter family Aldedh PF00171.22 KKK18199.1 - 3.5e-138 461.0 0.1 3.4e-80 269.8 0.0 2.0 1 1 1 2 2 2 2 Aldehyde dehydrogenase family LuxC PF05893.14 KKK18199.1 - 0.17 10.9 0.1 0.26 10.3 0.1 1.2 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) Alpha-amylase PF00128.24 KKK18200.1 - 1.2e-110 370.3 0.9 1.9e-110 369.6 0.9 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Malt_amylase_C PF16657.5 KKK18200.1 - 9.8e-05 22.4 0.0 0.00021 21.4 0.0 1.6 1 0 0 1 1 1 1 Maltogenic Amylase, C-terminal domain hDGE_amylase PF14701.6 KKK18200.1 - 0.0033 16.6 0.0 0.0053 15.9 0.0 1.2 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain Glyco_transf_25 PF01755.17 KKK18201.1 - 0.0012 18.8 0.0 0.78 9.6 0.0 2.6 2 1 0 2 2 2 2 Glycosyltransferase family 25 (LPS biosynthesis protein) Peptidase_M19 PF01244.21 KKK18202.1 - 4.9e-102 341.4 0.0 5.7e-102 341.2 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) Amidohydro_2 PF04909.14 KKK18202.1 - 0.074 12.8 0.0 0.21 11.3 0.0 1.8 2 0 0 2 2 2 0 Amidohydrolase AIM5 PF17050.5 KKK18202.1 - 0.087 13.6 0.0 0.25 12.2 0.0 1.8 1 0 0 1 1 1 0 Altered inheritance of mitochondria 5 AIG2_2 PF13772.6 KKK18203.1 - 1.1e-07 32.1 0.0 1.8e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 AIG2-like family GGACT PF06094.12 KKK18203.1 - 0.00047 20.7 0.0 0.00085 19.9 0.0 1.4 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like Zn_clus PF00172.18 KKK18204.1 - 6.1e-09 35.9 7.3 1e-08 35.1 7.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Haem_bd PF14376.6 KKK18204.1 - 0.81 9.6 2.6 0.52 10.3 0.7 1.6 2 0 0 2 2 2 0 Haem-binding domain MaoC_dehydratas PF01575.19 KKK18205.1 - 1.4e-26 92.4 0.0 2.9e-26 91.4 0.0 1.5 2 0 0 2 2 2 1 MaoC like domain MaoC_dehydrat_N PF13452.6 KKK18205.1 - 1.9e-06 28.0 0.0 0.00017 21.7 0.0 2.4 2 1 0 2 2 2 2 N-terminal half of MaoC dehydratase Polyketide_cyc2 PF10604.9 KKK18206.1 - 2.2e-07 31.2 0.0 2.5e-07 31.1 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport His_Phos_1 PF00300.22 KKK18207.1 - 0.25 11.0 0.0 0.42 10.3 0.0 1.3 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) MFS_1 PF07690.16 KKK18208.1 - 2.7e-46 158.1 49.8 1.7e-43 148.9 48.3 2.9 2 1 0 2 2 2 2 Major Facilitator Superfamily Sulfatase PF00884.23 KKK18209.1 - 1.3e-21 77.3 0.3 2e-21 76.7 0.3 1.2 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 KKK18209.1 - 1.2e-06 28.4 0.0 1.9e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 KKK18209.1 - 0.08 12.3 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Metalloenzyme superfamily DUF229 PF02995.17 KKK18209.1 - 0.18 10.4 0.0 0.28 9.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Peptidase_S9 PF00326.21 KKK18211.1 - 2.4e-54 184.0 0.1 3.6e-54 183.5 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family PD40 PF07676.12 KKK18211.1 - 0.00014 21.7 0.3 0.14 12.1 0.1 3.0 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat Kri1 PF05178.12 KKK18212.1 - 0.01 16.3 0.2 0.012 16.1 0.2 1.1 1 0 0 1 1 1 0 KRI1-like family Pectinesterase PF01095.19 KKK18213.1 - 3.2e-162 538.3 84.4 1.3e-44 152.2 6.7 7.6 7 1 0 7 7 7 5 Pectinesterase DUF1788 PF08747.11 KKK18213.1 - 0.072 13.1 0.0 0.25 11.3 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1788) HSDR_N_2 PF13588.6 KKK18214.1 - 0.0087 16.0 0.0 2.5 8.1 0.0 2.5 2 0 0 2 2 2 2 Type I restriction enzyme R protein N terminus (HSDR_N) Choline_kinase PF01633.20 KKK18214.1 - 0.031 13.9 0.0 1.3 8.5 0.0 2.4 2 0 0 2 2 2 0 Choline/ethanolamine kinase Sporozoite_P67 PF05642.11 KKK18214.1 - 0.075 11.1 0.2 0.1 10.6 0.2 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Glyco_hydro_35 PF01301.19 KKK18214.1 - 0.11 12.1 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolases family 35 Acetyltransf_1 PF00583.25 KKK18216.1 - 1.2e-05 25.6 0.0 1.6e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KKK18216.1 - 2.2e-05 24.8 0.0 3.7e-05 24.1 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KKK18216.1 - 6.8e-05 23.1 0.0 0.00017 21.8 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KKK18216.1 - 0.01 15.8 0.0 0.015 15.2 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KKK18216.1 - 0.021 15.5 0.0 0.026 15.2 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Anoctamin PF04547.12 KKK18217.1 - 8.9e-118 394.0 4.2 1.1e-117 393.6 4.2 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel GST_N_2 PF13409.6 KKK18217.1 - 2.9e-18 65.9 0.0 6.5e-18 64.8 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KKK18217.1 - 3.9e-10 39.6 0.0 1e-09 38.3 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KKK18217.1 - 0.035 14.3 0.0 0.1 12.8 0.0 1.8 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain ECF_trnsprt PF12822.7 KKK18217.1 - 0.04 14.0 7.6 0.044 13.9 2.6 2.8 2 1 0 2 2 2 0 ECF transporter, substrate-specific component GST_C_6 PF17171.4 KKK18217.1 - 0.081 12.7 0.0 0.27 11.1 0.0 1.9 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain cNMP_binding PF00027.29 KKK18218.1 - 2.6e-30 104.3 1.6 3.7e-19 68.6 0.0 5.6 5 1 1 6 6 6 4 Cyclic nucleotide-binding domain Patatin PF01734.22 KKK18218.1 - 2.5e-18 67.0 6.4 7.6e-17 62.2 6.4 2.6 1 1 0 1 1 1 1 Patatin-like phospholipase Ribonuclease_3 PF00636.26 KKK18219.1 - 6.4e-41 139.2 0.0 4e-22 78.8 0.0 2.9 3 0 0 3 3 3 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 KKK18219.1 - 5.5e-29 100.9 0.0 5e-15 55.8 0.0 3.6 3 0 0 3 3 3 2 Ribonuclease-III-like Dicer_dimer PF03368.14 KKK18219.1 - 1.1e-21 76.8 0.0 2.7e-21 75.5 0.0 1.7 1 0 0 1 1 1 1 Dicer dimerisation domain DEAD PF00270.29 KKK18219.1 - 9e-19 67.9 0.0 1.9e-18 66.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KKK18219.1 - 7.9e-15 55.2 0.0 2.1e-14 53.8 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KKK18219.1 - 1.5e-09 38.1 0.0 2.7e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit bZIP_1 PF00170.21 KKK18220.1 - 1e-09 38.3 10.0 7.1e-09 35.6 10.0 2.1 1 1 0 1 1 1 1 bZIP transcription factor PRKG1_interact PF15898.5 KKK18220.1 - 0.012 16.5 0.8 0.023 15.6 0.8 1.6 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain DUF3138 PF11336.8 KKK18220.1 - 0.044 12.4 0.1 0.059 12.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) bZIP_2 PF07716.15 KKK18220.1 - 0.48 10.5 15.8 30 4.8 14.1 2.7 2 1 0 2 2 2 0 Basic region leucine zipper Ndc1_Nup PF09531.10 KKK18220.1 - 2.9 6.4 5.5 3.2 6.3 5.5 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup An_peroxidase PF03098.15 KKK18240.1 - 6.1e-37 127.4 0.0 2.7e-25 89.0 0.0 3.9 1 1 1 2 2 2 2 Animal haem peroxidase p450 PF00067.22 KKK18240.1 - 5.6e-06 25.4 0.0 0.00093 18.1 0.0 2.2 2 0 0 2 2 2 2 Cytochrome P450 TPR_1 PF00515.28 KKK18241.1 - 5.8e-36 120.9 23.0 5.6e-07 29.1 0.1 10.6 9 1 1 10 10 10 7 Tetratricopeptide repeat TPR_2 PF07719.17 KKK18241.1 - 1.7e-34 115.1 23.8 7.1e-06 25.8 0.1 9.8 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_8 PF13181.6 KKK18241.1 - 1.1e-23 81.4 16.0 0.0002 21.3 0.0 9.6 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_16 PF13432.6 KKK18241.1 - 1.5e-22 80.0 12.2 1.1e-06 29.2 0.2 5.9 5 1 1 6 6 6 5 Tetratricopeptide repeat TPR_11 PF13414.6 KKK18241.1 - 1.5e-19 69.4 21.0 1.8e-06 27.5 0.0 7.5 5 1 2 7 7 7 6 TPR repeat TPR_12 PF13424.6 KKK18241.1 - 1.7e-17 63.5 23.1 0.00075 19.7 2.2 7.3 3 1 4 7 7 7 5 Tetratricopeptide repeat TPR_17 PF13431.6 KKK18241.1 - 3.5e-16 58.3 4.6 0.048 14.0 0.0 7.8 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_9 PF13371.6 KKK18241.1 - 1.9e-14 53.5 5.4 5.6e-07 29.6 0.2 4.9 2 1 3 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 KKK18241.1 - 2.9e-13 50.1 17.4 5.5e-05 23.6 0.8 6.3 5 1 1 7 7 6 4 Tetratricopeptide repeat TPR_14 PF13428.6 KKK18241.1 - 1.8e-12 47.0 12.2 0.024 15.4 0.1 8.1 3 2 6 9 9 7 3 Tetratricopeptide repeat TPR_7 PF13176.6 KKK18241.1 - 9e-12 44.2 10.5 0.024 14.6 0.1 7.6 6 2 1 7 7 7 3 Tetratricopeptide repeat ANAPC3 PF12895.7 KKK18241.1 - 1.4e-07 31.6 13.8 0.036 14.3 0.0 5.2 3 1 3 6 6 6 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 KKK18241.1 - 2.4e-07 30.4 15.1 0.23 11.4 0.4 7.8 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_MalT PF17874.1 KKK18241.1 - 1.1e-05 24.9 2.1 1.1e-05 24.9 2.1 2.7 1 1 2 3 3 3 2 MalT-like TPR region SHNi-TPR PF10516.9 KKK18241.1 - 1.4e-05 24.5 8.3 0.066 12.7 0.1 5.4 5 0 0 5 5 5 2 SHNi-TPR MAS20 PF02064.15 KKK18241.1 - 0.00013 22.0 8.8 0.025 14.6 1.5 4.2 4 1 1 5 5 4 1 MAS20 protein import receptor TPR_15 PF13429.6 KKK18241.1 - 0.00068 18.9 9.2 0.11 11.6 1.7 5.0 2 2 2 4 4 4 1 Tetratricopeptide repeat Sel1 PF08238.12 KKK18241.1 - 0.0024 18.5 3.5 0.87 10.4 0.2 3.9 3 0 0 3 3 3 1 Sel1 repeat ARL6IP6 PF15062.6 KKK18241.1 - 0.0036 17.4 0.1 0.0091 16.1 0.1 1.6 1 0 0 1 1 1 1 Haemopoietic lineage transmembrane helix AP3D1 PF06375.11 KKK18241.1 - 0.0072 16.6 4.6 0.016 15.4 4.6 1.5 1 0 0 1 1 1 1 AP-3 complex subunit delta-1 TPR_4 PF07721.14 KKK18241.1 - 0.011 16.3 0.1 33 5.5 0.0 5.0 5 0 0 5 5 4 0 Tetratricopeptide repeat SPO22 PF08631.10 KKK18241.1 - 0.015 14.8 0.5 1 8.8 0.0 3.2 2 1 1 3 3 3 0 Meiosis protein SPO22/ZIP4 like TPR_6 PF13174.6 KKK18241.1 - 0.022 15.4 23.2 8.5 7.2 0.6 8.3 9 0 0 9 9 8 0 Tetratricopeptide repeat ANAPC5 PF12862.7 KKK18241.1 - 0.19 11.8 8.2 17 5.6 0.3 4.4 2 2 1 3 3 3 0 Anaphase-promoting complex subunit 5 Usp PF00582.26 KKK18241.1 - 0.19 12.2 8.6 1.4 9.5 1.6 3.5 4 0 0 4 4 3 0 Universal stress protein family NARP1 PF12569.8 KKK18241.1 - 0.3 10.0 20.7 0.25 10.2 0.2 4.0 2 1 1 3 3 3 0 NMDA receptor-regulated protein 1 MIT PF04212.18 KKK18241.1 - 2.7 8.1 14.7 36 4.5 0.9 5.8 6 0 0 6 6 5 0 MIT (microtubule interacting and transport) domain Aminotran_4 PF01063.19 KKK18242.1 - 1.1e-37 130.1 0.0 1.3e-37 129.8 0.0 1.0 1 0 0 1 1 1 1 Amino-transferase class IV PRELI PF04707.14 KKK18243.1 - 1.7e-22 80.0 0.0 1.8e-20 73.3 0.0 2.2 2 0 0 2 2 2 2 PRELI-like family DUF3445 PF11927.8 KKK18245.1 - 2.4e-55 187.6 0.0 3e-55 187.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) PALP PF00291.25 KKK18246.1 - 5.3e-76 255.8 1.8 6.8e-76 255.5 1.8 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.18 KKK18246.1 - 9.7e-46 153.5 0.0 1.3e-22 79.4 0.0 2.4 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase Ribosomal_L36 PF00444.18 KKK18247.1 - 1.8e-06 28.1 10.5 0.00046 20.3 1.0 2.3 1 1 1 2 2 2 2 Ribosomal protein L36 Aldedh PF00171.22 KKK18248.1 - 2.9e-166 553.5 0.7 3.3e-166 553.4 0.7 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 KKK18248.1 - 0.15 11.5 0.0 0.69 9.3 0.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1487) Abhydrolase_1 PF00561.20 KKK18249.1 - 6.1e-48 163.7 0.0 1.2e-46 159.5 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 KKK18249.1 - 0.00012 21.8 0.0 0.00023 20.9 0.0 1.4 1 0 0 1 1 1 1 Putative esterase NFACT-R_1 PF05670.13 KKK18250.1 - 3.4e-27 95.3 0.0 5.8e-27 94.5 0.0 1.4 1 0 0 1 1 1 1 NFACT protein RNA binding domain DUF1330 PF07045.11 KKK18250.1 - 0.0027 18.0 0.0 0.021 15.1 0.0 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF1330) Cu-oxidase_3 PF07732.15 KKK18251.1 - 4.8e-10 39.5 0.0 7.5e-08 32.4 0.0 2.3 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 KKK18251.1 - 1.1e-07 31.7 0.0 0.0049 16.6 0.0 3.1 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.22 KKK18251.1 - 0.034 14.3 0.0 0.055 13.6 0.0 1.3 1 0 0 1 1 1 0 Multicopper oxidase Mtc PF03820.17 KKK18252.1 - 1.5e-99 333.0 0.1 1.3e-48 165.6 0.0 2.1 1 1 0 2 2 2 2 Tricarboxylate carrier WD40 PF00400.32 KKK18252.1 - 1.7e-16 60.3 17.8 0.00016 22.4 0.1 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKK18252.1 - 2.7e-07 30.8 0.2 0.032 14.5 0.0 4.7 5 1 1 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain 4HBT_3 PF13622.6 KKK18253.1 - 1.6e-24 87.5 0.4 2.1e-24 87.1 0.4 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 KKK18253.1 - 4.1e-05 23.4 0.1 0.00053 19.8 0.0 2.4 2 1 1 3 3 3 1 Acyl-CoA thioesterase SLC35F PF06027.12 KKK18254.1 - 5.7e-99 331.4 20.5 6.7e-99 331.2 20.5 1.0 1 0 0 1 1 1 1 Solute carrier family 35 CRT-like PF08627.10 KKK18254.1 - 5e-10 38.8 1.6 8.4e-10 38.1 1.6 1.3 1 0 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like EamA PF00892.20 KKK18254.1 - 2.5e-06 27.7 31.7 0.0022 18.2 10.0 2.1 2 0 0 2 2 2 2 EamA-like transporter family PIG-U PF06728.13 KKK18255.1 - 4.6e-121 404.5 30.3 5.8e-121 404.1 30.3 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U 8TM_micro PF17028.5 KKK18255.1 - 0.61 9.7 12.7 1.1 8.9 12.7 1.4 1 0 0 1 1 1 0 8TM Microsporidial transmembrane domain Pescadillo_N PF06732.11 KKK18256.1 - 5.6e-125 416.4 0.0 5.6e-125 416.4 0.0 1.7 2 0 0 2 2 2 1 Pescadillo N-terminus BRCT_2 PF16589.5 KKK18256.1 - 0.00019 21.8 0.1 0.0021 18.4 0.1 2.4 1 1 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 KKK18256.1 - 0.011 16.1 0.0 0.4 11.1 0.0 3.1 2 1 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 KKK18256.1 - 0.17 12.2 0.1 0.47 10.8 0.1 1.8 1 1 0 1 1 1 0 DNA ligase 3 BRCT domain DUF2457 PF10446.9 KKK18256.1 - 3.6 6.6 35.7 6.8 5.7 35.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Aldo_ket_red PF00248.21 KKK18257.1 - 2.6e-51 174.6 0.0 3e-50 171.1 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Acetyltransf_1 PF00583.25 KKK18258.1 - 0.00011 22.5 0.2 0.00019 21.7 0.2 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KKK18258.1 - 0.00021 21.2 0.0 0.00037 20.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KKK18258.1 - 0.0078 16.6 0.2 0.013 15.9 0.2 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KKK18258.1 - 0.12 12.4 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein Fumarate_red_D PF02313.17 KKK18259.1 - 0.038 14.1 3.8 0.17 12.0 3.3 2.1 1 1 1 2 2 2 0 Fumarate reductase subunit D CMD PF02627.20 KKK18260.1 - 1.6e-07 31.3 0.4 4.7e-07 29.8 0.2 1.9 2 1 0 2 2 2 1 Carboxymuconolactone decarboxylase family CPSase_L_D3 PF02787.19 KKK18260.1 - 0.025 14.9 0.0 0.037 14.4 0.0 1.2 1 0 0 1 1 1 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain GBP_C PF02841.14 KKK18260.1 - 0.067 12.6 0.1 0.092 12.1 0.1 1.1 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain HD_2 PF12917.7 KKK18260.1 - 0.15 11.8 0.0 0.21 11.3 0.0 1.2 1 0 0 1 1 1 0 HD containing hydrolase-like enzyme Exo_endo_phos PF03372.23 KKK18261.1 - 3.9e-09 36.4 0.0 7.6e-09 35.4 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LIDHydrolase PF10230.9 KKK18262.1 - 3.4e-78 262.9 0.0 1.1e-77 261.1 0.0 1.8 1 1 0 1 1 1 1 Lipid-droplet associated hydrolase Abhydrolase_6 PF12697.7 KKK18262.1 - 1.6e-05 25.7 3.0 0.003 18.2 0.9 2.3 2 1 0 2 2 2 2 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KKK18262.1 - 0.00019 20.8 0.2 0.00056 19.3 0.2 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DUF900 PF05990.12 KKK18262.1 - 0.029 13.9 0.1 0.056 13.0 0.0 1.5 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) DUF1057 PF06342.12 KKK18262.1 - 0.039 13.0 0.0 0.86 8.6 0.0 2.3 2 1 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF1057) Thioesterase PF00975.20 KKK18262.1 - 0.052 13.7 0.0 0.21 11.7 0.0 2.0 2 0 0 2 2 2 0 Thioesterase domain PGAP1 PF07819.13 KKK18262.1 - 0.1 12.3 0.1 0.32 10.7 0.0 1.8 2 0 0 2 2 2 0 PGAP1-like protein DCP1 PF06058.13 KKK18263.1 - 4.6e-27 94.3 0.0 7.5e-27 93.6 0.0 1.3 1 0 0 1 1 1 1 Dcp1-like decapping family MAGI_u1 PF16663.5 KKK18263.1 - 0.6 10.2 2.5 3.7 7.7 0.2 2.5 2 0 0 2 2 2 0 Unstructured region on MAGI SMK-1 PF04802.15 KKK18264.1 - 2e-78 262.7 1.2 3.2e-78 262.0 1.2 1.4 1 0 0 1 1 1 1 Component of IIS longevity pathway SMK-1 STE3 PF02076.15 KKK18265.1 - 2.3e-50 171.5 17.7 1.1e-42 146.2 4.7 3.9 1 1 2 3 3 3 3 Pheromone A receptor SSB PF00436.25 KKK18266.1 - 5.2e-19 68.2 0.0 6.5e-19 67.9 0.0 1.1 1 0 0 1 1 1 1 Single-strand binding protein family HSBP1 PF06825.12 KKK18267.1 - 0.073 12.9 0.2 0.25 11.2 0.0 1.9 2 0 0 2 2 2 0 Heat shock factor binding protein 1 ABC_membrane PF00664.23 KKK18268.1 - 3.8e-79 266.2 30.8 6.2e-45 154.0 12.3 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KKK18268.1 - 1.1e-51 175.0 0.0 2.8e-30 105.6 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KKK18268.1 - 2.4e-09 37.0 3.8 0.0042 16.5 0.2 4.2 2 2 0 4 4 4 3 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 KKK18268.1 - 7.6e-06 26.0 0.4 0.21 11.7 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KKK18268.1 - 4.1e-05 23.6 0.0 0.015 15.2 0.0 2.6 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 KKK18268.1 - 7.7e-05 23.1 0.3 0.014 15.8 0.2 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 KKK18268.1 - 0.00024 20.8 0.2 0.6 9.9 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 KKK18268.1 - 0.00059 19.7 1.5 0.34 10.7 0.0 3.5 2 1 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system Dynamin_N PF00350.23 KKK18268.1 - 0.00098 19.2 0.3 0.19 11.8 0.0 2.8 2 0 0 2 2 2 1 Dynamin family AAA_30 PF13604.6 KKK18268.1 - 0.0019 18.0 1.1 0.22 11.2 0.0 3.1 2 1 0 2 2 2 1 AAA domain AAA_23 PF13476.6 KKK18268.1 - 0.005 17.4 1.3 0.33 11.4 0.0 2.8 3 0 0 3 3 2 1 AAA domain 60KD_IMP PF02096.20 KKK18268.1 - 0.01 15.7 6.1 0.041 13.8 6.1 2.0 1 0 0 1 1 1 0 60Kd inner membrane protein AAA_15 PF13175.6 KKK18268.1 - 0.018 14.7 0.3 0.52 10.0 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain DUF87 PF01935.17 KKK18268.1 - 0.053 13.6 0.4 1.4 8.9 0.0 2.6 2 0 0 2 2 2 0 Helicase HerA, central domain Roc PF08477.13 KKK18268.1 - 0.077 13.2 0.4 39 4.5 0.0 3.5 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase IstB_IS21 PF01695.17 KKK18268.1 - 0.73 9.5 2.5 6.5 6.4 0.0 3.2 4 0 0 4 4 4 0 IstB-like ATP binding protein AAA_22 PF13401.6 KKK18268.1 - 3.1 8.1 5.3 36 4.6 0.1 3.6 4 0 0 4 4 3 0 AAA domain NACHT PF05729.12 KKK18268.1 - 6.5 6.6 5.4 2.7 7.9 0.1 2.7 3 0 0 3 3 3 0 NACHT domain Pkinase PF00069.25 KKK18269.1 - 1.8e-56 191.4 0.0 1.5e-50 172.0 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KKK18269.1 - 2.2e-26 92.7 0.0 3.3e-23 82.3 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase FHA PF00498.26 KKK18269.1 - 6.3e-09 36.1 0.0 1.6e-08 34.7 0.0 1.8 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.6 KKK18269.1 - 9.3e-06 25.2 0.0 1.6e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KKK18269.1 - 2.3e-05 23.4 0.0 5e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KKK18269.1 - 7.4e-05 22.2 0.0 0.00015 21.1 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KKK18269.1 - 0.00057 19.9 1.3 0.0085 16.0 0.0 2.2 1 1 0 2 2 2 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 KKK18269.1 - 0.018 14.6 0.3 0.094 12.2 0.0 2.0 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Yop-YscD_cpl PF16697.5 KKK18269.1 - 0.045 14.1 0.0 0.12 12.7 0.0 1.8 1 0 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain DUF3627 PF12299.8 KKK18269.1 - 0.14 12.3 0.2 0.39 10.8 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3627) Myb_DNA-bind_6 PF13921.6 KKK18270.1 - 0.0002 21.5 0.1 0.00034 20.8 0.1 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KKK18270.1 - 0.01 16.0 0.2 0.02 15.0 0.2 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain Rap1_C PF11626.8 KKK18270.1 - 0.017 15.2 0.1 0.026 14.6 0.1 1.3 1 0 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Adap_comp_sub PF00928.21 KKK18271.1 - 6.9e-84 281.3 0.0 8.5e-84 281.0 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KKK18271.1 - 0.00024 21.0 0.1 0.00042 20.3 0.1 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.9 KKK18271.1 - 0.013 15.0 0.2 0.022 14.2 0.2 1.4 1 0 0 1 1 1 0 Muniscin C-terminal mu homology domain DUF4203 PF13886.6 KKK18272.1 - 1.4e-52 178.3 23.5 1.9e-52 177.9 23.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) Erf4 PF10256.9 KKK18272.1 - 2.7e-40 137.1 0.0 5e-40 136.2 0.0 1.5 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family PgaD PF13994.6 KKK18272.1 - 0.081 13.0 0.1 0.3 11.1 0.1 1.9 1 0 0 1 1 1 0 PgaD-like protein bVLRF1 PF18826.1 KKK18273.1 - 4.1e-66 221.4 0.3 9e-66 220.3 0.3 1.6 1 0 0 1 1 1 1 bacteroidetes VLRF1 release factor Ank_5 PF13857.6 KKK18273.1 - 0.00015 22.0 0.0 0.0003 21.0 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Neogenin_C PF06583.12 KKK18273.1 - 0.00033 20.6 0.8 0.00033 20.6 0.8 2.3 2 0 0 2 2 2 1 Neogenin C-terminus Ank PF00023.30 KKK18273.1 - 0.0029 18.0 0.4 0.0097 16.3 0.4 1.9 1 0 0 1 1 1 1 Ankyrin repeat zf-C2H2_2 PF12756.7 KKK18273.1 - 0.015 15.6 0.3 0.033 14.5 0.3 1.5 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 KKK18273.1 - 0.13 12.6 1.4 0.26 11.6 1.4 1.5 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding Guanylate_kin PF00625.21 KKK18274.1 - 1e-22 80.7 0.1 1.1e-22 80.7 0.1 1.0 1 0 0 1 1 1 1 Guanylate kinase AA_permease PF00324.21 KKK18275.1 - 3e-132 441.6 35.0 3.7e-132 441.3 35.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KKK18275.1 - 1.2e-37 129.8 38.8 1.7e-37 129.3 38.7 1.3 1 1 0 1 1 1 1 Amino acid permease Dcc1 PF09724.9 KKK18276.1 - 0.018 14.3 0.0 0.03 13.6 0.0 1.3 1 1 0 1 1 1 0 Sister chromatid cohesion protein Dcc1 NicO PF03824.16 KKK18277.1 - 4.1e-62 210.1 11.5 6.3e-59 199.6 4.5 2.7 2 1 1 3 3 3 2 High-affinity nickel-transport protein 2Fe-2S_thioredx PF01257.19 KKK18279.1 - 7.4e-21 74.5 0.0 9.9e-21 74.1 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin A_deaminase PF00962.22 KKK18280.1 - 2.2e-82 277.1 0.0 2.5e-82 276.9 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase TFCD_C PF12612.8 KKK18297.1 - 1.2e-28 100.2 0.2 5.9e-28 98.0 0.1 2.3 2 0 0 2 2 2 1 Tubulin folding cofactor D C terminal RRM_1 PF00076.22 KKK18297.1 - 8.9e-12 44.7 0.2 2.2e-11 43.4 0.2 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HEAT_2 PF13646.6 KKK18297.1 - 1.6e-05 25.2 4.8 0.087 13.2 0.1 5.5 6 0 0 6 6 6 1 HEAT repeats HEAT PF02985.22 KKK18297.1 - 4.1e-05 23.5 6.8 0.18 12.1 0.0 6.3 6 0 0 6 6 6 1 HEAT repeat IFRD PF05004.13 KKK18297.1 - 0.0033 16.6 0.3 0.01 15.0 0.3 1.8 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) RRM_5 PF13893.6 KKK18297.1 - 0.0034 17.0 0.0 0.0078 15.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Arm PF00514.23 KKK18297.1 - 0.042 13.9 0.1 1.8 8.7 0.0 3.2 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 KKK18297.1 - 0.049 14.2 2.2 6.5 7.4 0.0 4.7 4 0 0 4 4 4 0 HEAT-like repeat Vac14_Fab1_bd PF12755.7 KKK18297.1 - 0.082 13.5 0.0 0.73 10.5 0.0 2.7 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region HEAT_PBS PF03130.16 KKK18297.1 - 0.21 12.4 1.8 77 4.4 0.1 4.7 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat HR1 PF02185.16 KKK18300.1 - 3.7e-28 97.4 19.9 1.6e-15 57.0 4.5 2.7 3 0 0 3 3 3 2 Hr1 repeat C1_1 PF00130.22 KKK18300.1 - 4.6e-21 74.5 28.6 2.6e-12 46.4 9.2 2.2 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) C2 PF00168.30 KKK18300.1 - 2.3e-05 24.6 0.0 5e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 C2 domain DUF4726 PF15855.5 KKK18300.1 - 0.048 13.9 0.6 0.048 13.9 0.6 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4726) zf-RING_9 PF13901.6 KKK18300.1 - 0.65 9.9 21.5 0.54 10.2 7.2 2.3 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon Uds1 PF15456.6 KKK18300.1 - 1.4 9.1 6.3 0.7 10.1 0.9 2.5 2 0 0 2 2 2 0 Up-regulated During Septation Fungal_trans PF04082.18 KKK18301.1 - 6.2e-14 51.7 0.0 1.2e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK18301.1 - 3e-08 33.7 8.9 5.9e-08 32.7 8.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_3 PF01494.19 KKK18302.1 - 3.8e-17 62.6 0.2 2.3e-07 30.4 0.0 3.1 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.24 KKK18302.1 - 0.0002 21.1 0.0 0.24 10.9 0.0 2.1 1 1 1 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KKK18302.1 - 0.00024 20.5 0.0 0.00039 19.8 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 KKK18302.1 - 0.0016 17.6 0.0 0.038 13.0 0.0 2.1 2 0 0 2 2 2 1 Squalene epoxidase NAD_binding_8 PF13450.6 KKK18302.1 - 0.0018 18.5 0.0 0.004 17.4 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KKK18302.1 - 0.15 12.0 0.0 0.28 11.2 0.0 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding Myb_DNA-binding PF00249.31 KKK18303.1 - 9.9e-34 115.3 11.3 1.9e-11 44.0 1.1 3.2 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KKK18303.1 - 1.8e-28 98.6 7.7 1.1e-14 54.4 1.4 3.3 2 1 1 3 3 3 3 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 KKK18303.1 - 4.3e-07 30.0 4.6 0.00018 21.6 0.1 3.1 2 1 1 3 3 3 2 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_7 PF15963.5 KKK18303.1 - 0.00034 20.4 0.2 0.0052 16.7 0.0 2.4 2 1 0 2 2 2 1 Myb DNA-binding like MADF_DNA_bdg PF10545.9 KKK18303.1 - 0.00061 20.0 1.5 0.46 10.8 0.2 2.6 2 0 0 2 2 2 2 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_2 PF08914.11 KKK18303.1 - 0.0094 16.1 0.9 12 6.2 0.2 3.2 2 1 1 3 3 3 2 Rap1 Myb domain Myb_DNA-bind_4 PF13837.6 KKK18303.1 - 0.028 14.8 10.2 9.6 6.7 0.1 3.6 3 1 0 3 3 3 0 Myb/SANT-like DNA-binding domain Spore_III_AB PF09548.10 KKK18303.1 - 0.073 13.2 0.1 0.11 12.6 0.1 1.4 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) Lipase_GDSL_2 PF13472.6 KKK18304.1 - 2e-13 51.2 3.5 8.8e-13 49.0 3.5 1.9 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KKK18304.1 - 1.3e-09 38.3 0.0 1.9e-09 37.8 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.6 KKK18304.1 - 0.0073 16.4 0.0 0.012 15.8 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Ank_2 PF12796.7 KKK18305.1 - 4e-34 117.0 0.0 1.3e-14 54.5 0.0 4.1 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KKK18305.1 - 3.5e-26 88.4 0.5 0.00065 20.0 0.0 7.3 7 0 0 7 7 7 6 Ankyrin repeat Ank_4 PF13637.6 KKK18305.1 - 1.4e-25 89.3 1.1 3.2e-06 27.6 0.0 5.5 2 1 4 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 KKK18305.1 - 2.2e-23 82.0 5.9 2.5e-08 34.0 0.0 5.4 5 1 1 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.30 KKK18305.1 - 1e-21 76.3 0.3 0.00055 20.3 0.0 7.0 7 0 0 7 7 7 5 Ankyrin repeat F-box-like PF12937.7 KKK18305.1 - 0.021 14.7 0.0 0.051 13.5 0.0 1.7 1 0 0 1 1 1 0 F-box-like F-box PF00646.33 KKK18305.1 - 0.19 11.7 0.1 0.34 10.8 0.1 1.4 1 0 0 1 1 1 0 F-box domain Zn_clus PF00172.18 KKK18307.1 - 7.7e-08 32.3 10.0 7.7e-08 32.3 10.0 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Methyltransf_31 PF13847.6 KKK18308.1 - 1.7e-27 96.1 0.0 2.2e-27 95.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKK18308.1 - 6e-23 81.4 0.0 1e-22 80.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KKK18308.1 - 7.1e-23 81.1 0.0 1.1e-22 80.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KKK18308.1 - 4.1e-16 59.0 0.0 5.7e-16 58.6 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 KKK18308.1 - 3.1e-15 56.7 0.0 4.7e-15 56.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KKK18308.1 - 2.4e-13 50.3 0.0 2.9e-13 50.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 KKK18308.1 - 3.6e-09 36.5 0.0 5.3e-09 35.9 0.0 1.1 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW PCMT PF01135.19 KKK18308.1 - 1.8e-08 34.4 0.0 2.4e-08 34.0 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 KKK18308.1 - 7.1e-06 25.7 0.0 1.1e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain DREV PF05219.12 KKK18308.1 - 1.9e-05 23.9 0.0 2.6e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 DREV methyltransferase NodS PF05401.11 KKK18308.1 - 5.4e-05 22.9 0.0 7.8e-05 22.4 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_4 PF02390.17 KKK18308.1 - 7e-05 22.4 0.0 9.3e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_9 PF08003.11 KKK18308.1 - 0.00029 19.9 0.0 0.00041 19.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_29 PF03141.16 KKK18308.1 - 0.0055 15.3 0.0 0.0072 14.9 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase RrnaAD PF00398.20 KKK18308.1 - 0.0064 15.6 0.0 0.0085 15.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_2 PF00891.18 KKK18308.1 - 0.0092 15.3 0.0 0.012 14.9 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase domain Methyltr_RsmB-F PF01189.17 KKK18308.1 - 0.035 13.7 0.0 0.051 13.2 0.0 1.2 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F CMAS PF02353.20 KKK18308.1 - 0.049 12.9 0.0 0.063 12.6 0.0 1.1 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.7 KKK18308.1 - 0.053 13.5 0.0 0.083 12.8 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain PLDc_2 PF13091.6 KKK18333.1 - 1.7e-14 53.8 0.2 1.1e-06 28.6 0.0 3.8 3 1 0 3 3 3 2 PLD-like domain PLDc PF00614.22 KKK18333.1 - 1.5e-12 47.1 2.5 2.3e-05 24.4 0.3 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif Regulator_TrmB PF11495.8 KKK18333.1 - 0.27 10.4 0.2 1.2 8.2 0.0 2.0 2 0 0 2 2 2 0 Archaeal transcriptional regulator TrmB DEAD PF00270.29 KKK18334.1 - 1.9e-16 60.3 0.0 4.1e-16 59.2 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KKK18334.1 - 1.8e-10 41.1 0.0 5.7e-10 39.5 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KKK18334.1 - 2.6e-06 27.7 0.0 7.3e-06 26.3 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Glyco_transf_15 PF01793.16 KKK18334.1 - 0.1 11.8 0.6 0.2 10.9 0.6 1.5 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase Cyanate_lyase PF02560.14 KKK18335.1 - 2.9e-24 84.7 0.0 7.2e-24 83.4 0.0 1.7 1 0 0 1 1 1 1 Cyanate lyase C-terminal domain zf-C2H2_4 PF13894.6 KKK18335.1 - 1.2e-10 41.3 15.9 0.35 11.8 0.0 6.4 6 0 0 6 6 6 4 C2H2-type zinc finger zf-C2H2 PF00096.26 KKK18335.1 - 1.3e-10 41.1 12.2 0.065 13.7 0.0 6.2 6 0 0 6 6 6 3 Zinc finger, C2H2 type zf-Di19 PF05605.12 KKK18335.1 - 7e-06 26.2 9.9 0.021 15.1 2.5 3.7 2 1 0 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding Rad50_zn_hook PF04423.14 KKK18335.1 - 3.2e-05 23.7 10.5 0.00012 21.8 0.1 4.5 2 1 2 4 4 4 1 Rad50 zinc hook motif zf-H2C2_2 PF13465.6 KKK18335.1 - 0.00022 21.5 12.3 0.38 11.3 0.3 4.6 4 0 0 4 4 4 2 Zinc-finger double domain zf-RING_4 PF14570.6 KKK18335.1 - 0.0011 18.7 10.3 7.1 6.5 0.1 4.5 4 0 0 4 4 4 0 RING/Ubox like zinc-binding domain zf-C2H2_9 PF16293.5 KKK18335.1 - 0.005 16.7 9.6 3.7 7.5 0.0 5.7 4 2 3 7 7 5 1 C2H2 type zinc-finger (1 copy) zf-C2H2_jaz PF12171.8 KKK18335.1 - 0.0072 16.6 10.1 1.4 9.3 1.0 5.7 5 1 1 6 6 6 1 Zinc-finger double-stranded RNA-binding HTH_31 PF13560.6 KKK18335.1 - 0.011 16.0 0.0 0.034 14.5 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain DUF2225 PF09986.9 KKK18335.1 - 0.013 15.2 8.6 0.11 12.2 0.0 4.0 3 1 1 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2225) CpXC PF14353.6 KKK18335.1 - 0.015 15.4 9.7 0.64 10.1 0.4 3.8 2 1 1 3 3 3 0 CpXC protein zf-C2H2_8 PF15909.5 KKK18335.1 - 0.019 15.3 8.0 0.46 10.8 0.2 3.3 2 1 1 3 3 3 0 C2H2-type zinc ribbon zinc_ribbon_4 PF13717.6 KKK18335.1 - 0.045 13.7 11.1 7.8 6.5 0.2 3.8 3 1 0 3 3 3 0 zinc-ribbon domain zf-RING_14 PF17978.1 KKK18335.1 - 0.064 13.7 4.2 0.15 12.5 0.5 2.6 2 1 1 3 3 3 0 RING/Ubox like zinc-binding domain GAGA PF09237.11 KKK18335.1 - 0.069 13.0 3.5 0.08 12.8 0.1 2.6 3 0 0 3 3 3 0 GAGA factor FOXP-CC PF16159.5 KKK18335.1 - 0.077 13.6 7.8 4.2 8.1 0.0 4.1 2 1 2 4 4 4 0 FOXP coiled-coil domain Zn-ribbon_8 PF09723.10 KKK18335.1 - 0.093 12.9 18.2 0.13 12.4 2.2 4.3 2 1 3 5 5 5 0 Zinc ribbon domain zf-RRN7 PF11781.8 KKK18335.1 - 0.19 11.4 1.4 4.6 7.0 0.2 2.8 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 zf-met PF12874.7 KKK18335.1 - 0.28 11.6 9.2 17 6.0 0.0 5.0 6 0 0 6 6 5 0 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 KKK18335.1 - 0.36 11.2 13.3 3.3 8.1 2.9 3.6 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-CSL PF05207.13 KKK18335.1 - 0.4 10.4 5.3 2.4 7.9 0.4 2.9 2 0 0 2 2 2 0 CSL zinc finger IBR PF01485.21 KKK18335.1 - 0.57 10.4 16.2 0.94 9.7 6.9 3.7 3 1 1 4 4 3 0 IBR domain, a half RING-finger domain HNH_5 PF14279.6 KKK18335.1 - 0.7 9.8 7.6 5.5 6.9 2.1 3.3 3 0 0 3 3 3 0 HNH endonuclease zf-C2H2_6 PF13912.6 KKK18335.1 - 0.8 9.8 14.1 7.2 6.7 0.2 5.1 5 0 0 5 5 5 0 C2H2-type zinc finger PhnA_Zn_Ribbon PF08274.12 KKK18335.1 - 0.87 9.6 7.4 0.17 11.8 0.3 3.2 3 1 0 3 3 2 0 PhnA Zinc-Ribbon DZR PF12773.7 KKK18335.1 - 1 9.5 15.5 0.83 9.7 6.0 3.3 2 1 0 2 2 2 0 Double zinc ribbon DUF3797 PF12677.7 KKK18335.1 - 1.1 9.2 3.6 33 4.5 0.0 4.0 4 0 0 4 4 4 0 Domain of unknown function (DUF3797) zinc_ribbon_9 PF14369.6 KKK18335.1 - 1.6 9.1 8.8 36 4.7 0.3 4.2 4 0 0 4 4 4 0 zinc-ribbon zinc_ribbon_5 PF13719.6 KKK18335.1 - 1.8 8.4 10.1 24 4.8 0.1 3.9 3 1 0 3 3 3 0 zinc-ribbon domain zf-C2HC_2 PF13913.6 KKK18335.1 - 3 7.9 10.2 6.1 6.9 0.2 4.2 4 0 0 4 4 4 0 zinc-finger of a C2HC-type Prok-RING_1 PF14446.6 KKK18335.1 - 8 6.5 10.5 20 5.2 3.2 3.8 3 1 0 3 3 3 0 Prokaryotic RING finger family 1 PKS_DE PF18369.1 KKK18335.1 - 9.8 6.8 6.0 17 6.1 0.4 2.9 3 0 0 3 3 2 0 Polyketide synthase dimerisation element domain Homeodomain PF00046.29 KKK18336.1 - 1.4e-19 69.7 4.5 3.3e-19 68.5 4.5 1.7 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KKK18336.1 - 0.0011 18.8 1.1 0.0024 17.7 1.1 1.6 1 0 0 1 1 1 1 Homeobox KN domain PGP_phosphatase PF09419.10 KKK18337.1 - 3.3e-58 196.0 0.0 4.5e-58 195.6 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.6 KKK18337.1 - 1.3e-05 25.1 0.1 2.3e-05 24.4 0.1 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 KKK18337.1 - 0.1 12.9 0.0 17 5.6 0.0 2.2 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase LSM PF01423.22 KKK18338.1 - 0.052 13.2 0.1 0.06 13.0 0.1 1.1 1 0 0 1 1 1 0 LSM domain Dus PF01207.17 KKK18339.1 - 3.7e-55 187.2 0.0 5.9e-55 186.5 0.0 1.2 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) DHO_dh PF01180.21 KKK18339.1 - 0.009 15.2 0.0 0.015 14.5 0.0 1.3 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase CENP-X PF09415.10 KKK18340.1 - 1.3e-13 51.0 1.1 5.2e-10 39.5 0.1 2.6 1 1 1 2 2 2 2 CENP-S associating Centromere protein X FAM60A PF15396.6 KKK18340.1 - 0.046 13.7 3.9 0.051 13.6 3.9 1.2 1 0 0 1 1 1 0 Protein Family FAM60A Dicty_REP PF05086.12 KKK18340.1 - 0.89 7.5 8.1 0.93 7.4 8.1 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Apt1 PF10351.9 KKK18340.1 - 0.91 8.3 9.5 0.92 8.3 9.5 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain SPX PF03105.19 KKK18340.1 - 1.1 9.1 16.9 1.2 9.0 16.9 1.1 1 0 0 1 1 1 0 SPX domain Ndc1_Nup PF09531.10 KKK18340.1 - 3.7 6.1 14.5 4.1 6.0 14.5 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Presenilin PF01080.17 KKK18340.1 - 7.2 5.3 4.8 7.6 5.2 4.8 1.1 1 0 0 1 1 1 0 Presenilin Macro PF01661.21 KKK18341.1 - 2.2e-10 40.6 0.0 9.9e-10 38.5 0.0 1.9 1 1 0 1 1 1 1 Macro domain 2C_adapt PF08793.10 KKK18341.1 - 0.11 12.7 0.0 0.22 11.7 0.0 1.4 1 0 0 1 1 1 0 2-cysteine adaptor domain DUF202 PF02656.15 KKK18342.1 - 0.0039 17.6 0.3 0.0039 17.6 0.3 3.2 2 1 1 3 3 3 1 Domain of unknown function (DUF202) Claudin_2 PF13903.6 KKK18342.1 - 0.023 14.5 4.3 4.7 6.9 3.2 3.0 2 1 1 3 3 3 0 PMP-22/EMP/MP20/Claudin tight junction DUF4395 PF14340.6 KKK18342.1 - 0.25 11.7 7.9 0.041 14.2 2.2 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4395) zf-C2H2 PF00096.26 KKK18343.1 - 1.9e-08 34.3 12.1 0.00032 21.0 3.2 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KKK18343.1 - 0.00015 22.1 4.8 0.00015 22.1 4.8 3.9 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KKK18343.1 - 0.0032 18.2 2.4 0.0032 18.2 2.4 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger FOXP-CC PF16159.5 KKK18343.1 - 0.029 15.0 9.7 0.5 11.0 0.5 3.3 3 1 1 4 4 4 0 FOXP coiled-coil domain zf-C2H2_6 PF13912.6 KKK18343.1 - 1.1 9.4 9.8 3.1 7.9 0.6 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger BCNT PF07572.12 KKK18344.1 - 9.4e-26 89.7 0.1 3e-25 88.1 0.1 1.9 1 0 0 1 1 1 1 Bucentaur or craniofacial development Glyco_hydro_28 PF00295.17 KKK18346.1 - 3.1e-122 407.7 18.5 3.6e-122 407.5 18.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Ribonuclease_T2 PF00445.18 KKK18347.1 - 1e-34 120.4 0.7 1.3e-34 120.1 0.7 1.1 1 0 0 1 1 1 1 Ribonuclease T2 family GT-D PF08759.11 KKK18347.1 - 0.017 14.8 0.7 0.025 14.2 0.7 1.2 1 0 0 1 1 1 0 Glycosyltransferase GT-D fold Mis12 PF05859.12 KKK18348.1 - 2.7e-47 160.2 0.0 4.5e-47 159.5 0.0 1.4 1 0 0 1 1 1 1 Mis12 protein DUF4865 PF16157.5 KKK18348.1 - 0.14 12.1 0.0 0.24 11.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4865) Amidohydro_1 PF01979.20 KKK18349.1 - 2.6e-06 27.0 0.0 4.9e-06 26.1 0.0 1.5 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_2 PF04909.14 KKK18349.1 - 1.9e-05 24.6 0.0 2.7e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase bZIP_1 PF00170.21 KKK18350.1 - 1.5e-05 25.0 1.0 3.2e-05 24.0 1.0 1.5 1 0 0 1 1 1 1 bZIP transcription factor Chorion_2 PF03964.15 KKK18350.1 - 0.014 16.3 2.7 0.014 16.3 2.7 1.9 2 0 0 2 2 2 0 Chorion family 2 Ribosomal_60s PF00428.19 KKK18350.1 - 0.56 10.8 3.8 0.95 10.1 3.8 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein MJ1316 PF04457.12 KKK18351.1 - 9e-17 61.6 1.9 1.4e-16 61.0 0.8 2.0 1 1 1 2 2 2 1 MJ1316 RNA cyclic group end recognition domain MIF PF01187.18 KKK18351.1 - 5.5e-07 29.9 0.4 8.7e-07 29.2 0.4 1.3 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) Glyco_hydro_76 PF03663.14 KKK18355.1 - 4.3e-152 506.9 20.6 5e-152 506.6 20.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Cytokin_check_N PF10407.9 KKK18356.1 - 4.2e-07 29.8 0.0 1.1e-06 28.5 0.0 1.7 1 0 0 1 1 1 1 Cdc14 phosphatase binding protein N-terminus 4HB_MCP_1 PF12729.7 KKK18356.1 - 0.022 14.3 7.5 0.041 13.4 7.5 1.4 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction LUC7 PF03194.15 KKK18356.1 - 0.056 13.1 5.5 0.13 11.9 5.5 1.6 1 0 0 1 1 1 0 LUC7 N_terminus Pro_isomerase PF00160.21 KKK18357.1 - 9.8e-52 175.4 0.1 1.8e-51 174.5 0.1 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.32 KKK18357.1 - 3.9e-12 46.5 0.0 0.00042 21.1 0.0 4.8 4 0 0 4 4 4 3 WD domain, G-beta repeat Ge1_WD40 PF16529.5 KKK18357.1 - 0.0015 17.6 0.1 0.19 10.7 0.0 3.1 2 1 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein ANAPC4_WD40 PF12894.7 KKK18357.1 - 0.0051 17.1 0.0 1.8 9.0 0.0 2.9 2 1 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Cpn60_TCP1 PF00118.24 KKK18358.1 - 1.1e-143 479.4 13.8 1.3e-143 479.2 13.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family CRM1_repeat PF18777.1 KKK18358.1 - 0.098 12.2 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 Chromosome region maintenance or exportin repeat FlgM PF04316.13 KKK18358.1 - 0.1 13.0 0.7 2.3 8.6 0.0 2.8 2 0 0 2 2 2 0 Anti-sigma-28 factor, FlgM PAD_M PF08527.10 KKK18358.1 - 0.13 12.0 0.5 0.9 9.2 0.1 2.2 2 0 0 2 2 2 0 Protein-arginine deiminase (PAD) middle domain CO_deh_flav_C PF03450.17 KKK18358.1 - 0.19 11.9 1.3 2.5 8.3 0.1 2.8 2 0 0 2 2 2 0 CO dehydrogenase flavoprotein C-terminal domain Isochorismatase PF00857.20 KKK18359.1 - 8.3e-24 84.7 0.1 9.8e-24 84.5 0.1 1.1 1 0 0 1 1 1 1 Isochorismatase family Ank_2 PF12796.7 KKK18360.1 - 2.4e-35 121.0 0.0 4.4e-09 36.8 0.0 4.5 3 1 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KKK18360.1 - 4e-30 103.8 4.7 0.00014 22.4 0.1 7.9 4 2 3 8 8 8 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 KKK18360.1 - 7.3e-24 81.3 2.9 0.0067 16.9 0.0 9.7 10 0 0 10 10 10 5 Ankyrin repeat Ank_5 PF13857.6 KKK18360.1 - 3e-21 75.2 6.7 2.6e-06 27.6 0.1 6.2 5 2 2 7 7 7 5 Ankyrin repeats (many copies) Ank PF00023.30 KKK18360.1 - 6.3e-20 70.7 8.1 0.22 12.0 0.1 9.7 10 0 0 10 10 10 5 Ankyrin repeat DUF2639 PF11121.8 KKK18360.1 - 0.092 12.8 0.0 0.22 11.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2639) Fungal_trans PF04082.18 KKK18361.1 - 7e-17 61.3 0.7 1e-13 50.9 0.0 2.6 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK18361.1 - 2.3e-09 37.2 11.8 4.4e-09 36.3 11.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mucin PF01456.17 KKK18361.1 - 0.23 11.4 23.7 0.6 10.1 23.7 1.6 1 0 0 1 1 1 0 Mucin-like glycoprotein FSA_C PF10479.9 KKK18361.1 - 0.35 9.0 9.9 0.52 8.4 9.9 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus FAD_binding_7 PF03441.14 KKK18362.1 - 2.8e-82 275.1 0.7 4.7e-82 274.4 0.7 1.4 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 KKK18362.1 - 6.8e-42 143.3 0.2 1.1e-41 142.5 0.2 1.3 1 0 0 1 1 1 1 DNA photolyase Aminotran_4 PF01063.19 KKK18363.1 - 7.6e-25 88.1 0.0 1.1e-24 87.5 0.0 1.2 1 0 0 1 1 1 1 Amino-transferase class IV Glyco_transf_90 PF05686.12 KKK18390.1 - 6.7e-23 81.2 0.1 8.5e-23 80.9 0.1 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 90 p450 PF00067.22 KKK18391.1 - 4.8e-51 173.9 0.0 7.9e-51 173.2 0.0 1.2 1 1 0 1 1 1 1 Cytochrome P450 Phytochelatin_C PF09328.10 KKK18391.1 - 0.093 12.0 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1984) TPR_1 PF00515.28 KKK18392.1 - 2.8e-27 93.4 4.3 0.00044 20.0 0.3 9.9 10 0 0 10 10 10 6 Tetratricopeptide repeat ANAPC3 PF12895.7 KKK18392.1 - 1.1e-26 92.8 15.5 1.1e-22 80.0 0.9 6.0 6 0 0 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 KKK18392.1 - 9.1e-26 87.9 15.9 0.0085 16.1 0.2 10.6 11 0 0 11 11 10 7 Tetratricopeptide repeat TPR_19 PF14559.6 KKK18392.1 - 3.8e-21 75.3 12.4 0.00032 21.1 0.1 7.4 6 2 2 8 8 7 4 Tetratricopeptide repeat TPR_12 PF13424.6 KKK18392.1 - 3.9e-17 62.3 27.0 2.2e-08 34.3 0.2 9.9 7 3 2 9 9 9 3 Tetratricopeptide repeat TPR_8 PF13181.6 KKK18392.1 - 1.5e-14 52.9 4.9 0.53 10.6 0.1 8.8 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_16 PF13432.6 KKK18392.1 - 3.5e-12 46.8 27.4 0.54 10.9 1.0 8.4 7 2 2 9 9 9 7 Tetratricopeptide repeat TPR_14 PF13428.6 KKK18392.1 - 2.8e-11 43.2 23.2 2.4 9.2 0.3 10.2 7 3 4 11 11 10 2 Tetratricopeptide repeat TPR_11 PF13414.6 KKK18392.1 - 2.4e-10 39.9 0.5 0.37 10.5 0.1 8.1 8 1 1 9 9 9 2 TPR repeat TPR_10 PF13374.6 KKK18392.1 - 4e-09 36.1 17.5 0.00033 20.4 0.0 7.7 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_6 PF13174.6 KKK18392.1 - 2.7e-07 30.8 8.9 1.4 9.7 0.2 7.8 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_7 PF13176.6 KKK18392.1 - 2.9e-07 30.1 19.0 0.79 9.9 0.0 8.8 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_17 PF13431.6 KKK18392.1 - 1.9e-05 24.7 7.4 5 7.7 0.0 7.8 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_4 PF07721.14 KKK18392.1 - 0.00016 22.0 24.9 0.022 15.4 0.2 8.5 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_21 PF09976.9 KKK18392.1 - 0.0089 15.8 1.7 11 5.7 0.1 4.7 5 1 0 5 5 5 0 Tetratricopeptide repeat-like domain SRP_TPR_like PF17004.5 KKK18392.1 - 0.11 12.6 0.1 1.7 8.7 0.0 2.8 2 0 0 2 2 2 0 Putative TPR-like repeat TPR_MalT PF17874.1 KKK18392.1 - 1.3 8.4 15.1 0.015 14.7 2.4 3.6 4 2 0 4 4 4 0 MalT-like TPR region DUF572 PF04502.13 KKK18393.1 - 2.2e-69 234.7 19.3 2.5e-69 234.5 19.3 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) DUF4542 PF15075.6 KKK18393.1 - 0.038 14.4 0.4 0.17 12.3 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4542) Zn_ribbon_SprT PF17283.2 KKK18393.1 - 0.19 11.7 2.1 0.37 10.7 2.1 1.4 1 0 0 1 1 1 0 SprT-like zinc ribbon domain zf-ACC PF17848.1 KKK18393.1 - 0.29 11.2 3.0 0.87 9.7 0.5 2.4 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain BPL_N PF09825.9 KKK18393.1 - 10 5.1 7.5 14 4.6 7.5 1.2 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal FAT PF02259.23 KKK18394.1 - 1e-72 245.3 10.9 2.3e-72 244.1 10.9 1.6 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.27 KKK18394.1 - 1.3e-35 123.5 0.7 3.3e-35 122.1 0.1 2.1 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 KKK18394.1 - 1.7e-05 24.5 0.1 5e-05 23.0 0.1 1.9 1 0 0 1 1 1 1 FATC domain TPR_2 PF07719.17 KKK18394.1 - 1.7 9.0 3.5 19 5.7 0.2 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Tau95 PF09734.9 KKK18405.1 - 1.2e-44 152.5 0.3 2.3e-44 151.6 0.3 1.5 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain Tau95_N PF17682.1 KKK18405.1 - 1.6e-32 112.4 0.0 2.5e-32 111.7 0.0 1.4 1 0 0 1 1 1 1 Tau95 Triple barrel domain DUF4685 PF15737.5 KKK18405.1 - 0.033 14.6 0.1 0.077 13.4 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4685) Cwf_Cwc_15 PF04889.12 KKK18405.1 - 2.7 7.7 8.6 3.9 7.1 8.6 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein PfkB PF00294.24 KKK18406.1 - 2e-14 53.6 0.1 2.9e-14 53.1 0.1 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase ACP PF06857.11 KKK18406.1 - 0.11 12.8 0.3 0.37 11.1 0.0 2.0 2 0 0 2 2 2 0 Malonate decarboxylase delta subunit (MdcD) PfkB PF00294.24 KKK18407.1 - 1.4e-18 67.3 0.0 1.7e-18 67.0 0.0 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase HSDR_N_2 PF13588.6 KKK18407.1 - 0.042 13.8 0.0 0.061 13.3 0.0 1.3 1 0 0 1 1 1 0 Type I restriction enzyme R protein N terminus (HSDR_N) Vps54 PF07928.12 KKK18408.1 - 1.4e-49 168.0 1.7 1.6e-49 167.8 0.2 2.0 2 0 0 2 2 2 1 Vps54-like protein Vps54_N PF10475.9 KKK18408.1 - 1.4e-07 31.1 0.4 3.9e-07 29.6 0.4 1.7 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex LUC7 PF03194.15 KKK18408.1 - 0.15 11.7 0.2 0.4 10.3 0.2 1.7 1 0 0 1 1 1 0 LUC7 N_terminus DUF4363 PF14276.6 KKK18408.1 - 1.2 9.3 3.3 29 4.8 0.1 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4363) MCM PF00493.23 KKK18409.1 - 3.5e-103 343.5 0.1 7.4e-103 342.5 0.0 1.5 2 0 0 2 2 2 1 MCM P-loop domain MCM_OB PF17207.3 KKK18409.1 - 6.3e-37 126.2 0.3 1.2e-36 125.4 0.3 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KKK18409.1 - 1.2e-28 99.3 1.6 3e-28 98.1 1.6 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KKK18409.1 - 4.2e-15 56.2 0.0 1e-14 55.0 0.0 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 KKK18409.1 - 5.6e-06 25.9 0.0 0.00074 19.0 0.0 2.3 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KKK18409.1 - 4.5e-05 23.5 0.0 0.00011 22.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 KKK18409.1 - 0.00095 19.0 0.0 0.0036 17.2 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KKK18409.1 - 0.081 12.6 0.0 1.2 8.9 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain Imm35 PF15567.6 KKK18409.1 - 0.1 12.8 0.0 0.23 11.7 0.0 1.5 1 0 0 1 1 1 0 Immunity protein 35 adh_short PF00106.25 KKK18410.1 - 1.8e-31 109.1 0.0 1.1e-23 83.8 0.0 2.0 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KKK18410.1 - 9.2e-17 61.4 0.0 5.5e-13 49.0 0.0 2.0 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KKK18410.1 - 7.9e-09 35.7 0.0 1.2e-08 35.1 0.0 1.1 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KKK18410.1 - 0.14 11.3 0.0 0.21 10.7 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein GMC_oxred_N PF00732.19 KKK18411.1 - 2.9e-60 204.2 0.0 3.6e-60 203.9 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KKK18411.1 - 2.1e-29 102.9 0.0 3.8e-29 102.0 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KKK18411.1 - 3.7e-06 26.3 0.5 0.042 12.9 0.3 2.2 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 KKK18411.1 - 0.0021 17.2 0.3 0.0036 16.4 0.3 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 KKK18411.1 - 0.0045 17.2 0.2 0.016 15.4 0.2 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KKK18411.1 - 0.0062 16.2 2.0 0.047 13.3 0.8 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 KKK18411.1 - 0.014 14.7 0.1 0.024 13.9 0.1 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.6 KKK18411.1 - 0.036 13.3 0.2 1 8.6 0.3 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KKK18411.1 - 0.18 11.0 0.0 0.52 9.5 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_DMAT PF11991.8 KKK18412.1 - 5.5e-91 305.7 0.0 7.2e-91 305.3 0.0 1.1 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase APH PF01636.23 KKK18432.1 - 5.1e-13 49.5 0.0 2.4e-12 47.3 0.0 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KKK18432.1 - 0.033 13.8 2.0 0.043 13.4 0.1 1.9 2 0 0 2 2 2 0 Choline/ethanolamine kinase Frag1 PF10277.9 KKK18452.1 - 1e-41 142.9 6.7 1e-41 142.9 6.7 2.8 3 0 0 3 3 3 1 Frag1/DRAM/Sfk1 family Exo_endo_phos PF03372.23 KKK18452.1 - 0.17 11.3 0.0 0.36 10.3 0.0 1.4 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family DUF805 PF05656.14 KKK18452.1 - 4.5 7.7 0.0 4.5 7.7 0.0 4.2 4 0 0 4 4 4 0 Protein of unknown function (DUF805) RRM_1 PF00076.22 KKK18453.1 - 1.5e-09 37.6 0.0 2.8e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KKK18453.1 - 0.0072 15.9 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) COX6B PF02297.17 KKK18455.1 - 4.2e-23 81.4 5.1 6.7e-23 80.7 5.1 1.3 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb Abi_2 PF07751.11 KKK18455.1 - 0.045 14.0 0.3 0.076 13.3 0.3 1.3 1 0 0 1 1 1 0 Abi-like protein Pet191_N PF10203.9 KKK18455.1 - 0.056 13.8 1.2 0.11 12.9 1.2 1.4 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 SYS1 PF09801.9 KKK18456.1 - 6.4e-49 165.8 10.7 1.4e-48 164.7 10.7 1.5 1 1 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network Aldolase_II PF00596.21 KKK18457.1 - 1.2e-41 142.7 0.1 2.6e-41 141.6 0.1 1.5 1 1 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain COG5 PF10392.9 KKK18458.1 - 1.1e-40 138.9 3.8 2.8e-40 137.6 0.3 2.7 3 0 0 3 3 3 1 Golgi transport complex subunit 5 CENP-F_leu_zip PF10473.9 KKK18458.1 - 0.073 13.1 0.9 0.22 11.5 0.3 2.0 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 U3_assoc_6 PF08640.11 KKK18459.1 - 1.5e-30 105.1 0.7 3.5e-30 103.9 0.7 1.6 1 0 0 1 1 1 1 U3 small nucleolar RNA-associated protein 6 TPR_14 PF13428.6 KKK18459.1 - 0.0015 19.2 0.2 0.21 12.5 0.1 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat RF-1 PF00472.20 KKK18460.1 - 1.1e-18 67.2 0.5 1.6e-18 66.7 0.5 1.1 1 0 0 1 1 1 1 RF-1 domain Arginase PF00491.21 KKK18463.1 - 4e-75 252.9 0.0 5.1e-75 252.6 0.0 1.0 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.7 KKK18463.1 - 0.0022 18.3 0.0 0.0034 17.6 0.0 1.2 1 0 0 1 1 1 1 UPF0489 domain Ras PF00071.22 KKK18464.1 - 2.4e-52 176.8 0.0 2.7e-52 176.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KKK18464.1 - 7e-19 68.2 0.0 9.4e-19 67.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKK18464.1 - 4.2e-06 26.3 0.0 5.6e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family JAB PF01398.21 KKK18466.1 - 5.1e-33 113.5 0.0 1.1e-32 112.5 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 KKK18466.1 - 1.2e-12 48.2 1.3 2.2e-12 47.4 1.3 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.6 KKK18466.1 - 1.2e-07 31.5 0.0 2.8e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Hist_deacetyl PF00850.19 KKK18467.1 - 3.9e-82 276.2 0.0 7.3e-82 275.3 0.0 1.5 2 0 0 2 2 2 1 Histone deacetylase domain NIF PF03031.18 KKK18468.1 - 1.3e-41 142.0 0.1 1.8e-41 141.5 0.1 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Ribosomal_L14 PF00238.19 KKK18470.1 - 1e-34 119.2 0.0 1.2e-34 119.0 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Endonuc-FokI_C PF09254.11 KKK18470.1 - 0.12 11.6 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Restriction endonuclease FokI, C terminal Nucleoporin_C PF03177.14 KKK18471.1 - 1.2e-44 153.1 1.5 1.8e-44 152.5 1.5 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal DUF3802 PF12290.8 KKK18471.1 - 0.017 15.7 0.6 2.5 8.6 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3802) R3H PF01424.22 KKK18473.1 - 3.6e-12 46.1 0.0 9.2e-12 44.8 0.0 1.7 1 0 0 1 1 1 1 R3H domain G-patch PF01585.23 KKK18473.1 - 1.4e-09 37.7 0.3 3.7e-09 36.3 0.3 1.8 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 KKK18473.1 - 4.4e-05 23.5 0.1 0.00011 22.2 0.1 1.7 1 0 0 1 1 1 1 G-patch domain VCX_VCY PF15231.6 KKK18473.1 - 0.28 11.9 5.2 0.074 13.7 1.4 2.0 2 0 0 2 2 2 0 Variable charge X/Y family zf-C2H2_jaz PF12171.8 KKK18474.1 - 3.4e-11 43.1 15.0 1e-10 41.6 5.9 2.9 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KKK18474.1 - 1.4e-10 41.2 9.8 5e-08 33.1 2.7 2.6 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 KKK18474.1 - 7.5e-08 32.6 7.5 0.0041 17.8 0.7 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_2 PF12756.7 KKK18474.1 - 4.5e-06 26.9 9.0 0.00051 20.3 1.5 2.6 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.26 KKK18474.1 - 3.8e-05 23.9 10.1 0.025 15.0 1.3 3.1 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_3rep PF18868.1 KKK18474.1 - 0.0068 17.1 6.3 0.022 15.4 0.1 2.7 2 1 1 3 3 3 1 Zinc finger C2H2-type, 3 repeats zf-C2H2_6 PF13912.6 KKK18474.1 - 0.013 15.5 8.5 0.11 12.5 2.3 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KKK18474.1 - 0.026 14.9 8.1 0.23 11.9 0.2 3.4 3 0 0 3 3 3 0 Zinc-finger double domain zf-LYAR PF08790.11 KKK18474.1 - 0.27 11.2 5.4 0.17 11.8 0.7 2.6 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger LIM PF00412.22 KKK18474.1 - 0.33 11.2 5.3 1.2 9.4 1.5 2.4 2 0 0 2 2 2 0 LIM domain Mut7-C PF01927.16 KKK18474.1 - 0.35 11.0 5.0 0.55 10.3 1.7 2.2 2 0 0 2 2 2 0 Mut7-C RNAse domain MIEAP PF16026.5 KKK18474.1 - 1.2 9.3 9.9 0.61 10.3 6.4 2.2 2 1 0 2 2 2 0 Mitochondria-eating protein PhoD PF09423.10 KKK18502.1 - 6.5e-09 35.3 0.3 5.4e-05 22.4 0.3 2.5 2 1 0 2 2 2 2 PhoD-like phosphatase Rhomboid PF01694.22 KKK18503.1 - 9.3e-26 90.6 9.4 9.5e-26 90.6 8.1 1.6 2 0 0 2 2 2 1 Rhomboid family DUF2157 PF09925.9 KKK18503.1 - 0.0005 19.9 3.1 0.0015 18.3 3.1 1.8 1 1 0 1 1 1 1 Predicted membrane protein (DUF2157) TRM PF02005.16 KKK18504.1 - 7.2e-113 377.6 0.0 1.7e-98 330.2 0.0 2.1 1 1 1 2 2 2 2 N2,N2-dimethylguanosine tRNA methyltransferase Met_10 PF02475.16 KKK18504.1 - 0.00038 20.3 0.0 0.00069 19.4 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein zf-CCHC_3 PF13917.6 KKK18504.1 - 2.6 8.1 4.8 7.7 6.6 0.3 2.4 2 0 0 2 2 2 0 Zinc knuckle DUF1691 PF07950.11 KKK18505.1 - 2.6e-39 134.2 7.3 2.3e-32 111.9 5.5 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1691) Sdh_cyt PF01127.22 KKK18505.1 - 0.0013 18.8 3.0 0.25 11.4 0.9 2.5 2 0 0 2 2 2 2 Succinate dehydrogenase/Fumarate reductase transmembrane subunit MOSP_N PF02707.16 KKK18505.1 - 0.14 11.9 1.1 0.28 10.9 1.1 1.5 1 1 0 1 1 1 0 Major Outer Sheath Protein N-terminal region FAS_I_H PF18314.1 KKK18506.1 - 4.9e-78 261.4 0.0 4.9e-78 261.4 0.0 1.8 2 0 0 2 2 2 1 Fatty acid synthase type I helical domain Fas_alpha_ACP PF18325.1 KKK18506.1 - 6.4e-58 195.7 0.0 1.2e-57 194.7 0.0 1.5 1 0 0 1 1 1 1 Fatty acid synthase subunit alpha Acyl carrier domain ketoacyl-synt PF00109.26 KKK18506.1 - 7.2e-22 78.2 0.0 1.6e-21 77.1 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACPS PF01648.20 KKK18506.1 - 1.3e-18 67.2 0.0 2.9e-18 66.0 0.0 1.6 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Ketoacyl-synt_C PF02801.22 KKK18506.1 - 2.2e-12 47.0 0.0 5.6e-12 45.7 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.25 KKK18506.1 - 4.2e-06 26.4 0.0 4e-05 23.2 0.0 2.4 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KKK18506.1 - 7.5e-05 22.4 0.0 0.0019 17.8 0.0 2.4 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KKK18506.1 - 0.00093 19.2 1.2 0.0018 18.2 0.0 2.1 3 0 0 3 3 3 1 KR domain DUF5102 PF17104.5 KKK18506.1 - 0.02 15.0 0.7 0.12 12.4 0.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5102) RbsD_FucU PF05025.13 KKK18506.1 - 0.046 14.2 0.0 0.21 12.0 0.0 2.1 2 0 0 2 2 2 0 RbsD / FucU transport protein family DUF1031 PF06275.11 KKK18506.1 - 0.14 12.4 0.1 12 6.3 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1031) 4PPT_N PF17837.1 KKK18506.1 - 0.22 11.7 2.3 2.1 8.5 2.3 2.4 1 1 0 1 1 1 0 4'-phosphopantetheinyl transferase N-terminal domain zf-C2H2_jaz PF12171.8 KKK18507.1 - 0.00076 19.7 3.1 0.0012 19.1 3.1 1.3 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 KKK18507.1 - 0.0016 18.8 1.8 0.003 17.9 1.8 1.5 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-met PF12874.7 KKK18507.1 - 0.004 17.5 0.7 0.0067 16.8 0.7 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-LYAR PF08790.11 KKK18507.1 - 0.032 14.1 0.3 0.064 13.2 0.3 1.5 1 0 0 1 1 1 0 LYAR-type C2HC zinc finger zf-C2H2_2 PF12756.7 KKK18507.1 - 0.045 14.1 0.4 0.07 13.5 0.4 1.2 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 KKK18507.1 - 0.073 14.0 0.8 0.16 12.9 0.8 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger Herpes_capsid PF06112.11 KKK18507.1 - 8.6 6.4 9.9 19 5.3 9.9 1.6 1 1 0 1 1 1 0 Gammaherpesvirus capsid protein Transket_pyr PF02779.24 KKK18508.1 - 1.7e-45 154.9 0.0 2.4e-45 154.4 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KKK18508.1 - 3e-35 120.8 0.0 1.3e-34 118.8 0.0 2.0 2 0 0 2 2 2 1 Transketolase, C-terminal domain Metallophos PF00149.28 KKK18509.1 - 3.5e-11 44.0 3.7 6.1e-11 43.2 3.7 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase 5_nucleotid_C PF02872.18 KKK18509.1 - 0.02 15.1 0.0 0.038 14.2 0.0 1.5 1 0 0 1 1 1 0 5'-nucleotidase, C-terminal domain ADH_zinc_N PF00107.26 KKK18510.1 - 8.8e-15 54.8 0.0 1.6e-14 54.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KKK18510.1 - 0.054 13.4 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain DUF4265 PF14085.6 KKK18510.1 - 0.073 13.0 0.0 4.9 7.2 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4265) Amidase PF01425.21 KKK18511.1 - 2.5e-116 389.3 0.1 3e-116 389.1 0.1 1.0 1 0 0 1 1 1 1 Amidase DAO PF01266.24 KKK18512.1 - 3.1e-36 125.7 0.1 3.6e-36 125.5 0.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KKK18512.1 - 0.00038 20.6 0.0 0.0011 19.2 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KKK18512.1 - 0.00055 19.3 1.5 0.00084 18.6 0.0 2.1 2 0 0 2 2 2 1 Thi4 family DUF3889 PF13028.6 KKK18512.1 - 0.044 13.7 0.2 0.075 13.0 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3889) COPI_assoc PF08507.10 KKK18513.1 - 5.1e-31 107.4 8.8 6.6e-31 107.1 8.8 1.1 1 0 0 1 1 1 1 COPI associated protein Cg6151-P PF10233.9 KKK18513.1 - 0.24 11.7 7.8 0.44 10.9 7.7 1.6 1 1 0 1 1 1 0 Uncharacterized conserved protein CG6151-P ubiquitin PF00240.23 KKK18522.1 - 6.8e-34 115.4 0.6 1.2e-33 114.7 0.6 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 KKK18522.1 - 4.1e-16 58.6 0.7 7.1e-16 57.8 0.7 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ribosomal_S27 PF01599.19 KKK18522.1 - 1.4e-08 34.7 0.9 3e-08 33.7 0.0 2.0 2 0 0 2 2 2 1 Ribosomal protein S27a Ubiquitin_2 PF14560.6 KKK18522.1 - 3.7e-05 24.1 0.1 0.00018 21.9 0.1 2.0 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 KKK18522.1 - 0.0016 18.5 0.5 0.0038 17.3 0.5 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 KKK18522.1 - 0.0057 17.0 0.5 0.011 16.0 0.0 1.6 1 1 1 2 2 2 1 Ubiquitin-like domain TBK1_ULD PF18396.1 KKK18522.1 - 0.0072 16.2 0.0 0.011 15.6 0.0 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain DUF2407 PF10302.9 KKK18522.1 - 0.018 15.6 0.7 0.028 15.0 0.7 1.3 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 KKK18522.1 - 0.036 14.1 1.0 7.6 6.7 0.2 2.3 2 0 0 2 2 2 0 Ubiquitin-like domain zf-C2H2 PF00096.26 KKK18523.1 - 0.46 11.0 2.8 1.1 9.8 2.8 1.7 1 0 0 1 1 1 0 Zinc finger, C2H2 type SRP54 PF00448.22 KKK18524.1 - 2e-74 249.5 3.4 3.5e-74 248.7 3.4 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 KKK18524.1 - 1.9e-29 102.2 0.3 1.9e-29 102.2 0.3 4.0 3 1 0 3 3 2 1 Signal peptide binding domain SRP54_N PF02881.19 KKK18524.1 - 2e-20 72.8 0.5 5.1e-20 71.5 0.5 1.8 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain cobW PF02492.19 KKK18524.1 - 6.2e-07 29.2 0.2 1.6e-06 27.8 0.2 1.7 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.6 KKK18524.1 - 5.9e-06 26.7 0.1 2e-05 25.0 0.1 1.9 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KKK18524.1 - 2e-05 24.8 0.3 5.8e-05 23.3 0.1 2.0 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KKK18524.1 - 0.0001 22.8 0.0 0.00024 21.5 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain MeaB PF03308.16 KKK18524.1 - 0.00075 18.6 0.1 0.00075 18.6 0.1 2.5 2 2 1 3 3 3 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Zeta_toxin PF06414.12 KKK18524.1 - 0.00083 18.7 0.1 0.0017 17.7 0.1 1.5 1 0 0 1 1 1 1 Zeta toxin APS_kinase PF01583.20 KKK18524.1 - 0.0015 18.4 0.0 0.0032 17.4 0.0 1.5 1 0 0 1 1 1 1 Adenylylsulphate kinase CbiA PF01656.23 KKK18524.1 - 0.0021 18.1 0.0 0.0041 17.2 0.0 1.8 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain SRPRB PF09439.10 KKK18524.1 - 0.0021 17.5 1.1 1.5 8.3 0.9 3.1 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit AAA_30 PF13604.6 KKK18524.1 - 0.0022 17.7 0.6 0.0063 16.2 0.6 1.8 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KKK18524.1 - 0.0048 17.4 0.0 0.011 16.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 KKK18524.1 - 0.0056 16.7 0.3 0.014 15.4 0.3 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit MMR_HSR1 PF01926.23 KKK18524.1 - 0.0057 16.7 0.3 0.058 13.5 0.1 2.5 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.6 KKK18524.1 - 0.007 16.6 0.0 0.029 14.6 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 KKK18524.1 - 0.0094 16.2 0.0 0.019 15.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain 6PF2K PF01591.18 KKK18524.1 - 0.012 14.9 0.0 0.02 14.2 0.0 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase ATP_bind_1 PF03029.17 KKK18524.1 - 0.015 15.1 0.5 0.037 13.8 0.1 1.9 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Thymidylate_kin PF02223.17 KKK18524.1 - 0.019 14.7 0.2 0.063 13.0 0.1 2.0 2 0 0 2 2 1 0 Thymidylate kinase MobB PF03205.14 KKK18524.1 - 0.021 14.7 0.2 0.053 13.4 0.0 1.8 2 0 0 2 2 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_31 PF13614.6 KKK18524.1 - 0.089 12.7 0.1 0.2 11.5 0.1 1.7 1 0 0 1 1 1 0 AAA domain Arf PF00025.21 KKK18524.1 - 0.14 11.6 0.0 0.35 10.3 0.0 1.6 1 0 0 1 1 1 0 ADP-ribosylation factor family Rrp15p PF07890.12 KKK18525.1 - 2.6e-37 128.1 8.8 2.6e-37 128.1 8.8 2.2 2 0 0 2 2 2 1 Rrp15p bZIP_1 PF00170.21 KKK18526.1 - 3e-07 30.5 10.0 1.9e-05 24.6 10.6 2.7 1 1 1 2 2 2 1 bZIP transcription factor Hap4_Hap_bind PF10297.9 KKK18526.1 - 6.6e-07 29.2 6.7 6.6e-07 29.2 6.7 2.1 2 0 0 2 2 1 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 TRAF_BIRC3_bd PF16673.5 KKK18526.1 - 0.038 13.8 0.7 0.038 13.8 0.7 2.1 2 1 0 2 2 2 0 TNF receptor-associated factor BIRC3 binding domain DUF2408 PF10303.9 KKK18526.1 - 0.11 13.1 0.5 0.22 12.1 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) dsrm PF00035.26 KKK18526.1 - 0.11 13.3 0.0 0.24 12.1 0.0 1.5 1 0 0 1 1 1 0 Double-stranded RNA binding motif HIP1_clath_bdg PF16515.5 KKK18526.1 - 0.22 12.1 2.6 0.49 11.0 2.6 1.6 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF3584 PF12128.8 KKK18526.1 - 0.24 8.9 4.3 0.33 8.4 4.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Replic_Relax PF13814.6 KKK18526.1 - 0.85 9.6 3.2 0.52 10.3 1.2 1.6 2 0 0 2 2 2 0 Replication-relaxation FAM184 PF15665.5 KKK18526.1 - 1.3 8.8 7.8 2.1 8.1 7.8 1.3 1 1 0 1 1 1 0 Family with sequence similarity 184, A and B V_ATPase_I PF01496.19 KKK18526.1 - 1.8 6.4 3.4 2.2 6.1 3.4 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Spc29 PF17082.5 KKK18526.1 - 1.8 8.3 4.9 0.27 11.1 1.0 1.6 2 0 0 2 2 2 0 Spindle Pole Component 29 bZIP_2 PF07716.15 KKK18526.1 - 4.2 7.5 21.1 0.3 11.2 11.7 3.0 2 1 0 2 2 2 0 Basic region leucine zipper Glyco_hydro_71 PF03659.14 KKK18527.1 - 1.8e-127 425.3 0.6 2.7e-127 424.7 0.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 Peptidase_M18 PF02127.15 KKK18527.1 - 1.5e-121 406.2 0.0 1.6e-120 402.8 0.0 2.0 1 1 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) AMOP PF03782.17 KKK18527.1 - 0.2 11.7 0.0 0.41 10.7 0.0 1.4 1 0 0 1 1 1 0 AMOP domain Fer2 PF00111.27 KKK18528.1 - 7.1e-13 48.3 0.8 1e-12 47.8 0.8 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Mito_carr PF00153.27 KKK18529.1 - 9.9e-09 35.0 7.1 0.011 15.6 0.1 4.8 4 1 0 4 4 4 4 Mitochondrial carrier protein PBP1_TM PF14812.6 KKK18529.1 - 0.039 14.3 5.4 0.065 13.6 5.4 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Fungal_trans PF04082.18 KKK18530.1 - 8.5e-05 21.7 0.3 0.00012 21.2 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain RRM_1 PF00076.22 KKK18531.1 - 5.1e-80 263.3 3.6 1.3e-20 73.0 0.1 5.3 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 KKK18531.1 - 1.2e-28 99.0 0.5 8.6e-28 96.3 0.7 2.3 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain RRM_5 PF13893.6 KKK18531.1 - 3.7e-12 45.9 0.8 0.0024 17.5 0.0 5.1 3 2 2 5 5 5 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KKK18531.1 - 1.9e-05 24.7 0.9 9.7 6.4 0.0 5.4 4 3 0 4 4 4 2 RNA recognition motif Nup35_RRM_2 PF14605.6 KKK18531.1 - 3e-05 23.9 0.6 0.77 9.8 0.0 4.2 4 0 0 4 4 4 1 Nup53/35/40-type RNA recognition motif YflT PF11181.8 KKK18531.1 - 0.00021 21.7 0.9 0.046 14.2 0.7 2.8 2 0 0 2 2 2 1 Heat induced stress protein YflT CbiG_mid PF11761.8 KKK18531.1 - 0.00098 19.2 0.0 4.8 7.4 0.0 3.5 3 0 0 3 3 3 1 Cobalamin biosynthesis central region RRM_3 PF08777.11 KKK18531.1 - 0.0092 16.0 8.8 0.47 10.5 1.8 4.4 4 2 1 5 5 5 1 RNA binding motif AAR2 PF05282.11 KKK18531.1 - 0.074 12.5 1.1 0.13 11.6 1.1 1.5 1 0 0 1 1 1 0 AAR2 protein CSD PF00313.22 KKK18531.1 - 0.083 12.8 1.2 65 3.5 0.1 3.6 3 0 0 3 3 3 0 'Cold-shock' DNA-binding domain Fungal_trans PF04082.18 KKK18532.1 - 1.4e-09 37.3 0.0 3.2e-09 36.2 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain UBA2_C PF16195.5 KKK18532.1 - 9.2 7.0 12.8 1.7 9.4 8.4 1.9 2 0 0 2 2 2 0 SUMO-activating enzyme subunit 2 C-terminus SNF2_N PF00176.23 KKK18534.1 - 3.1e-64 216.9 0.0 5.5e-64 216.1 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KKK18534.1 - 3.9e-18 65.8 0.0 1.5e-17 63.9 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KKK18534.1 - 3.1e-08 33.8 0.0 2.8e-07 30.7 0.0 2.5 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 KKK18534.1 - 0.0017 17.6 0.0 0.0048 16.1 0.0 1.6 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 TFIIF_beta PF02270.15 KKK18534.1 - 0.0026 17.9 0.0 0.0065 16.6 0.0 1.7 1 0 0 1 1 1 1 TFIIF, beta subunit HTH domain Fungal_TACC PF12709.7 KKK18534.1 - 0.2 12.1 0.8 0.6 10.6 0.8 1.8 1 0 0 1 1 1 0 Fungal Transforming acidic coiled-coil (TACC) proteins TMCO5 PF14992.6 KKK18534.1 - 0.27 10.8 4.2 0.62 9.6 4.2 1.5 1 0 0 1 1 1 0 TMCO5 family ABC_tran_CTD PF16326.5 KKK18534.1 - 0.31 11.3 4.0 3.8 7.8 3.9 2.7 1 1 0 1 1 1 0 ABC transporter C-terminal domain ZapB PF06005.12 KKK18534.1 - 3.9 8.0 9.7 3.7 8.1 6.3 2.5 1 1 1 2 2 2 0 Cell division protein ZapB SpoIIIAH PF12685.7 KKK18536.1 - 0.028 14.2 7.1 0.047 13.5 7.1 1.3 1 0 0 1 1 1 0 SpoIIIAH-like protein Apt1 PF10351.9 KKK18536.1 - 0.045 12.6 6.8 0.05 12.5 6.8 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain CPSF100_C PF13299.6 KKK18536.1 - 0.18 12.0 2.6 0.28 11.4 2.6 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Macoilin PF09726.9 KKK18536.1 - 0.74 8.3 9.2 0.82 8.1 9.2 1.1 1 0 0 1 1 1 0 Macoilin family RNA_pol_Rpc4 PF05132.14 KKK18536.1 - 1.1 9.7 5.0 1.8 9.0 5.0 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 Plasmodium_Vir PF05795.11 KKK18536.1 - 3.1 7.1 6.2 4.2 6.7 6.2 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein RAP1 PF07218.11 KKK18536.1 - 3.8 5.7 14.9 4.9 5.3 14.9 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) NPR3 PF03666.13 KKK18536.1 - 4.1 6.1 8.3 21 3.7 7.7 1.9 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF1180 PF06679.12 KKK18536.1 - 4.7 7.6 9.9 7.6 6.9 9.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1180) Period_C PF12114.8 KKK18536.1 - 9.4 5.8 19.3 18 4.8 19.3 1.4 1 0 0 1 1 1 0 Period protein 2/3C-terminal region Fungal_trans_2 PF11951.8 KKK18537.1 - 2.7e-35 121.9 1.4 3.9e-35 121.4 1.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Sterol_MT_C PF08498.10 KKK18538.1 - 1.3e-30 105.5 0.2 2.2e-30 104.7 0.2 1.4 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.12 KKK18538.1 - 8.6e-22 77.6 0.0 1.5e-21 76.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKK18538.1 - 1.2e-19 70.8 0.0 2.4e-19 69.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KKK18538.1 - 1.5e-18 67.1 0.0 2.2e-18 66.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KKK18538.1 - 1e-12 47.9 0.0 1.5e-12 47.4 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 KKK18538.1 - 2.9e-12 46.4 0.0 4.8e-12 45.7 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 KKK18538.1 - 1.7e-10 41.0 0.0 2.9e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KKK18538.1 - 6.1e-10 39.7 0.0 1.2e-09 38.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KKK18538.1 - 1.4e-05 24.9 0.0 2.4e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.13 KKK18538.1 - 0.00023 20.7 0.0 0.00044 19.7 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_29 PF03141.16 KKK18538.1 - 0.00029 19.5 0.0 0.00041 19.1 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase RrnaAD PF00398.20 KKK18538.1 - 0.0018 17.4 0.0 0.0027 16.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_15 PF09445.10 KKK18538.1 - 0.0025 17.4 0.0 0.0038 16.8 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase MTS PF05175.14 KKK18538.1 - 0.0037 16.8 0.0 0.0071 15.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain MetW PF07021.12 KKK18538.1 - 0.005 16.4 0.0 0.0084 15.7 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_2 PF00891.18 KKK18538.1 - 0.0082 15.5 0.0 0.015 14.6 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase domain TehB PF03848.14 KKK18538.1 - 0.035 13.5 0.0 0.061 12.7 0.0 1.4 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_24 PF13578.6 KKK18538.1 - 0.036 15.1 0.1 0.16 13.0 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain UPF0020 PF01170.18 KKK18538.1 - 0.04 13.6 0.0 0.09 12.4 0.0 1.6 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 TSC21 PF15217.6 KKK18538.1 - 0.044 13.7 0.2 0.067 13.1 0.2 1.3 1 0 0 1 1 1 0 TSC21 family Methyltransf_32 PF13679.6 KKK18538.1 - 0.1 12.6 0.2 0.34 10.9 0.0 1.9 1 1 1 2 2 2 0 Methyltransferase domain FtsJ PF01728.19 KKK18538.1 - 0.15 12.2 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase Amidohydro_1 PF01979.20 KKK18539.1 - 6.5e-65 219.7 0.0 7.7e-65 219.5 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KKK18539.1 - 1.5e-06 28.0 0.3 0.00029 20.4 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family GDC-P PF02347.16 KKK18540.1 - 1.8e-176 587.2 1.0 8e-164 545.5 0.0 2.6 3 1 0 3 3 3 2 Glycine cleavage system P-protein Beta_elim_lyase PF01212.21 KKK18540.1 - 7.6e-06 25.4 0.2 2e-05 24.1 0.2 1.6 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 KKK18540.1 - 0.0086 15.4 0.9 0.043 13.1 0.0 2.1 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 KKK18540.1 - 0.013 14.7 0.1 0.092 11.9 0.0 2.0 2 0 0 2 2 2 0 Aminotransferase class I and II SPOR PF05036.13 KKK18540.1 - 0.019 15.3 0.0 0.095 13.1 0.0 2.2 1 0 0 1 1 1 0 Sporulation related domain Med27 PF11571.8 KKK18541.1 - 2.2e-23 82.4 0.2 4.7e-23 81.3 0.2 1.6 1 0 0 1 1 1 1 Mediator complex subunit 27 DUF812 PF05667.11 KKK18541.1 - 0.041 12.8 0.2 0.041 12.8 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF812) Peptidase_S28 PF05577.12 KKK18542.1 - 4e-52 177.5 0.2 1.9e-51 175.2 0.2 1.8 1 1 0 1 1 1 1 Serine carboxypeptidase S28 Aldedh PF00171.22 KKK18543.1 - 1.7e-127 425.8 0.0 1.9e-127 425.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 KKK18543.1 - 0.062 12.3 0.3 0.47 9.4 0.0 2.0 2 0 0 2 2 2 0 Acyl-CoA reductase (LuxC) adh_short_C2 PF13561.6 KKK18544.1 - 7.4e-57 192.6 0.4 8.4e-57 192.4 0.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KKK18544.1 - 4.1e-42 143.9 0.2 5.1e-42 143.6 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KKK18544.1 - 4.6e-09 36.4 1.1 6.6e-09 35.9 1.1 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 KKK18544.1 - 0.0093 15.9 0.2 0.019 14.9 0.2 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ChuX_HutX PF06228.13 KKK18544.1 - 0.017 14.9 0.2 0.85 9.4 0.0 2.4 1 1 1 2 2 2 0 Haem utilisation ChuX/HutX Epimerase PF01370.21 KKK18544.1 - 0.024 14.1 0.1 0.039 13.4 0.1 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 KKK18544.1 - 0.061 12.6 0.1 0.18 11.1 0.1 1.8 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain MFS_1 PF07690.16 KKK18545.1 - 2.6e-33 115.4 34.7 2.6e-33 115.4 34.7 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Gln-synt_C PF00120.24 KKK18546.1 - 6.4e-77 258.9 0.0 1.1e-76 258.1 0.0 1.3 2 0 0 2 2 2 1 Glutamine synthetase, catalytic domain Gln-synt_N_2 PF16952.5 KKK18546.1 - 0.0081 16.0 0.0 0.019 14.8 0.0 1.6 1 1 0 1 1 1 1 Glutamine synthetase N-terminal domain Pkinase PF00069.25 KKK18547.1 - 2e-49 168.3 0.2 7.9e-49 166.4 0.2 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK18547.1 - 1.6e-22 80.0 0.0 2.7e-22 79.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KKK18547.1 - 0.00042 20.3 0.1 0.00098 19.1 0.1 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 KKK18547.1 - 0.0023 17.6 1.0 0.011 15.4 1.0 1.9 1 1 0 1 1 1 1 RIO1 family Kdo PF06293.14 KKK18547.1 - 0.13 11.6 0.1 0.6 9.4 0.0 2.0 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 KKK18547.1 - 0.41 10.2 2.0 0.5 9.9 0.3 1.9 2 0 0 2 2 2 0 Choline/ethanolamine kinase eIF-3c_N PF05470.12 KKK18548.1 - 7.3e-155 516.6 27.6 7.3e-155 516.6 27.6 3.9 1 1 1 2 2 2 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.27 KKK18548.1 - 4.8e-14 52.7 1.7 8e-13 48.8 0.0 3.1 3 0 0 3 3 3 1 PCI domain DUF1385 PF07136.11 KKK18548.1 - 0.038 13.3 0.0 0.072 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1385) SDA1 PF05285.12 KKK18548.1 - 0.62 9.4 24.1 1.2 8.5 24.1 1.4 1 0 0 1 1 1 0 SDA1 Complex1_LYR PF05347.15 KKK18549.1 - 0.022 14.8 3.3 1.6 8.9 3.3 2.4 1 1 0 1 1 1 0 Complex 1 protein (LYR family) RRM_1 PF00076.22 KKK18550.1 - 2.1e-09 37.0 0.0 3.6e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KKK18550.1 - 0.0058 16.6 0.0 0.01 15.9 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 KKK18550.1 - 0.012 15.7 0.0 0.025 14.6 0.0 1.5 1 0 0 1 1 1 0 RNA binding motif Phosphoesterase PF04185.14 KKK18551.1 - 2.5e-32 112.4 4.1 8.4e-32 110.7 4.1 1.7 1 1 0 1 1 1 1 Phosphoesterase family RAC_head PF16717.5 KKK18552.1 - 4.7e-31 107.7 5.1 4.7e-31 107.7 5.1 3.2 3 1 0 3 3 3 1 Ribosome-associated complex head domain DnaJ PF00226.31 KKK18552.1 - 3.3e-18 65.6 0.4 1.9e-17 63.2 0.4 2.4 1 0 0 1 1 1 1 DnaJ domain V_ATPase_I PF01496.19 KKK18552.1 - 0.055 11.4 7.4 0.088 10.7 7.4 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Rnk_N PF14760.6 KKK18552.1 - 0.31 11.5 4.1 10 6.7 0.0 3.2 3 0 0 3 3 3 0 Rnk N-terminus LMBR1 PF04791.16 KKK18552.1 - 2.2 7.1 6.7 2.5 6.9 6.7 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Glyco_hydro_43 PF04616.14 KKK18561.1 - 1.2e-06 28.0 0.0 1.3e-06 27.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 zf-HC5HC2H_2 PF13832.6 KKK18562.1 - 5.4e-32 110.2 5.4 5.4e-32 110.2 5.4 2.3 2 0 0 2 2 2 1 PHD-zinc-finger like domain EPL1 PF10513.9 KKK18562.1 - 1e-31 110.5 0.1 3.2e-31 108.8 0.0 1.9 2 0 0 2 2 2 1 Enhancer of polycomb-like zf-HC5HC2H PF13771.6 KKK18562.1 - 2.9e-27 94.7 1.9 2.9e-27 94.7 1.9 2.9 3 0 0 3 3 3 1 PHD-like zinc-binding domain PHD_2 PF13831.6 KKK18562.1 - 1.6e-14 53.2 8.0 8.1e-14 50.9 2.3 2.6 2 0 0 2 2 2 2 PHD-finger PHD PF00628.29 KKK18562.1 - 3.3e-10 39.7 19.3 7.8e-09 35.3 9.5 2.6 2 0 0 2 2 2 2 PHD-finger zf-PHD-like PF15446.6 KKK18562.1 - 0.52 9.9 8.7 0.017 14.7 1.7 2.0 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain zf-RING-like PF08746.11 KKK18562.1 - 3.2 8.2 18.8 0.027 14.8 3.7 2.6 2 0 0 2 2 2 0 RING-like domain zf-RING_2 PF13639.6 KKK18562.1 - 9.2 6.7 20.4 0.52 10.7 1.7 2.4 2 0 0 2 2 2 0 Ring finger domain RRM_1 PF00076.22 KKK18563.1 - 3.5e-21 74.8 0.0 4.8e-21 74.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KKK18563.1 - 7.8e-05 22.3 0.0 0.0001 21.9 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Fungal_trans_2 PF11951.8 KKK18565.1 - 6.8e-15 54.8 8.6 5.5e-14 51.8 8.7 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans PF04082.18 KKK18565.1 - 0.029 13.4 2.0 0.042 12.9 0.1 1.9 2 0 0 2 2 2 0 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK18566.1 - 6.3e-08 32.6 12.0 1.5e-07 31.4 12.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PI-PLC-X PF00388.19 KKK18567.1 - 4.8e-61 204.6 0.0 7.9e-61 203.9 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 KKK18567.1 - 3.1e-40 137.1 0.1 6.4e-40 136.1 0.1 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain Ribosomal_L37 PF08561.10 KKK18568.1 - 4.8e-44 149.7 0.7 6.2e-44 149.4 0.7 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L37 GST_N_3 PF13417.6 KKK18569.1 - 2e-07 31.3 0.1 6.5e-07 29.7 0.1 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KKK18569.1 - 2.5e-05 24.2 0.0 4.5e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KKK18569.1 - 0.0031 17.8 0.0 0.007 16.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_5 PF16865.5 KKK18569.1 - 0.12 13.0 0.0 0.19 12.3 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Spherulin4 PF12138.8 KKK18570.1 - 1e-71 241.4 0.1 1.2e-71 241.2 0.1 1.0 1 0 0 1 1 1 1 Spherulation-specific family 4 GDP_Man_Dehyd PF16363.5 KKK18571.1 - 1.7e-37 129.6 0.0 9.2e-37 127.2 0.0 2.0 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KKK18571.1 - 7e-36 123.9 0.0 7.1e-35 120.6 0.0 2.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KKK18571.1 - 1.9e-08 33.8 0.0 5.5e-07 29.0 0.0 2.4 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 KKK18571.1 - 3.7e-06 26.3 0.0 4.5e-05 22.8 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.19 KKK18571.1 - 1.9e-05 23.9 0.0 0.00016 20.7 0.0 2.3 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.10 KKK18571.1 - 0.00084 19.3 0.0 0.0015 18.4 0.0 1.4 1 0 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.17 KKK18571.1 - 0.0051 15.9 0.0 0.055 12.6 0.0 2.4 2 1 0 2 2 2 1 RmlD substrate binding domain adh_short PF00106.25 KKK18571.1 - 0.047 13.1 0.0 0.085 12.3 0.0 1.5 1 0 0 1 1 1 0 short chain dehydrogenase DUF1349 PF07081.11 KKK18581.1 - 1.3e-28 99.9 0.0 1.6e-28 99.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1349) MFS_1 PF07690.16 KKK18582.1 - 4.6e-23 81.7 38.8 1.4e-13 50.5 16.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KKK18582.1 - 2.7e-06 26.1 21.3 4.5e-06 25.4 21.3 1.3 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Pox_A14 PF05767.12 KKK18582.1 - 0.045 13.9 0.2 0.045 13.9 0.2 2.5 3 0 0 3 3 3 0 Poxvirus virion envelope protein A14 DUF5357 PF17310.2 KKK18582.1 - 0.058 11.9 1.3 0.13 10.8 1.3 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5357) RACo_linker PF17650.1 KKK18583.1 - 0.18 11.7 0.1 0.29 11.0 0.1 1.3 1 0 0 1 1 1 0 RACo linker region Peptidase_C14 PF00656.22 KKK18585.1 - 3.3e-47 161.5 0.0 4e-47 161.2 0.0 1.1 1 0 0 1 1 1 1 Caspase domain VWA_3 PF13768.6 KKK18585.1 - 0.17 11.8 0.0 1.4 8.9 0.0 2.0 2 0 0 2 2 2 0 von Willebrand factor type A domain Fungal_trans PF04082.18 KKK18596.1 - 8.4e-21 74.2 0.1 1.3e-20 73.5 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 KKK18596.1 - 1.3e-08 34.8 14.0 0.0005 20.4 1.4 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KKK18596.1 - 9.1e-07 29.0 5.8 9.1e-07 29.0 5.8 3.1 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KKK18596.1 - 0.0016 19.1 15.5 0.12 13.3 1.5 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger DUF4072 PF13284.6 KKK18596.1 - 0.052 14.0 2.3 0.15 12.5 2.3 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4072) SUIM_assoc PF16619.5 KKK18596.1 - 0.066 13.3 3.2 0.13 12.4 1.6 2.3 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 zf-C2H2_6 PF13912.6 KKK18596.1 - 0.5 10.4 4.3 1.3 9.1 4.3 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KKK18596.1 - 1.3 8.9 7.1 6.3 6.7 1.0 2.6 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2H2_jaz PF12171.8 KKK18596.1 - 1.8 8.9 3.4 3.1 8.2 0.5 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding DUF4291 PF14124.6 KKK18598.1 - 2.3e-54 184.0 0.9 2.8e-54 183.7 0.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4291) Methyltransf_23 PF13489.6 KKK18599.1 - 3.2e-21 75.9 0.0 4.8e-21 75.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KKK18599.1 - 9.7e-11 41.7 0.0 2.2e-09 37.3 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKK18599.1 - 9.9e-10 39.0 0.0 3e-09 37.4 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KKK18599.1 - 1.1e-05 26.0 0.0 2.7e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KKK18599.1 - 1.2e-05 26.0 0.0 8.1e-05 23.3 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KKK18599.1 - 0.0022 17.4 0.0 1.4 8.2 0.0 2.7 2 1 0 2 2 2 2 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 KKK18599.1 - 0.004 16.6 0.0 0.025 14.0 0.0 2.1 2 0 0 2 2 2 1 Putative methyltransferase RRN9 PF10680.9 KKK18599.1 - 0.029 14.6 0.1 2.7 8.3 0.1 2.4 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor MTS PF05175.14 KKK18599.1 - 0.088 12.4 0.0 0.22 11.1 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_16 PF10294.9 KKK18599.1 - 0.13 12.0 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase PrmA PF06325.13 KKK18599.1 - 0.18 11.2 0.0 0.31 10.4 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DHHC PF01529.20 KKK18600.1 - 2e-07 31.2 3.3 2.8e-07 30.7 3.3 1.2 1 0 0 1 1 1 1 DHHC palmitoyltransferase MpPF26 PF07666.11 KKK18600.1 - 0.38 10.9 2.9 0.58 10.3 2.9 1.2 1 0 0 1 1 1 0 M penetrans paralogue family 26 GP68 PF17469.2 KKK18601.1 - 0.19 12.2 0.0 0.24 11.8 0.0 1.2 1 0 0 1 1 1 0 Phage protein Gp68 Myosin_head PF00063.21 KKK18602.1 - 3.1e-272 904.8 0.2 7.7e-272 903.5 0.2 1.7 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_N PF02736.19 KKK18602.1 - 4.5e-10 39.2 0.0 1.3e-09 37.7 0.0 1.9 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain Myosin_tail_1 PF01576.19 KKK18602.1 - 1.2e-09 36.7 201.2 1.2e-09 36.7 201.2 5.3 1 1 1 2 2 2 1 Myosin tail GAS PF13851.6 KKK18602.1 - 0.00032 20.1 28.5 0.00032 20.1 28.5 14.4 2 2 13 17 17 17 2 Growth-arrest specific micro-tubule binding Muted PF14942.6 KKK18602.1 - 0.0013 19.1 12.0 0.0013 19.1 12.0 14.5 3 2 12 16 16 16 1 Organelle biogenesis, Muted-like protein AAA_22 PF13401.6 KKK18602.1 - 0.11 12.8 0.0 0.11 12.8 0.0 4.5 4 0 0 4 4 4 0 AAA domain zf-C3H1 PF10650.9 KKK18603.1 - 2.5e-12 46.3 3.4 4.6e-12 45.4 3.4 1.5 1 0 0 1 1 1 1 Putative zinc-finger domain APG6_N PF17675.1 KKK18603.1 - 0.0061 17.1 5.2 0.0061 17.1 5.2 3.3 3 0 0 3 3 3 1 Apg6 coiled-coil region Ribosomal_S19e PF01090.19 KKK18603.1 - 0.36 10.5 2.4 0.91 9.2 2.4 1.6 1 0 0 1 1 1 0 Ribosomal protein S19e SPT16 PF08644.11 KKK18603.1 - 4.6 7.4 6.0 1.1 9.5 0.6 2.4 2 0 0 2 2 2 0 FACT complex subunit (SPT16/CDC68) F-box-like PF12937.7 KKK18604.1 - 1.8e-07 30.9 0.1 4e-07 29.8 0.1 1.6 1 0 0 1 1 1 1 F-box-like POTRA_1 PF08478.10 KKK18604.1 - 0.016 15.5 0.0 0.037 14.3 0.0 1.6 1 0 0 1 1 1 0 POTRA domain, FtsQ-type F-box PF00646.33 KKK18604.1 - 0.07 13.0 0.0 0.07 13.0 0.0 3.3 5 0 0 5 5 5 0 F-box domain LRR_4 PF12799.7 KKK18604.1 - 4.8 7.8 12.4 5.4 7.6 0.2 4.8 3 1 2 5 5 5 0 Leucine Rich repeats (2 copies) tRNA-synt_2 PF00152.20 KKK18605.1 - 3.4e-70 236.6 0.1 4.7e-70 236.1 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) Hydrolase_6 PF13344.6 KKK18605.1 - 3.5e-24 84.8 0.0 9.8e-24 83.4 0.0 1.8 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KKK18605.1 - 1.9e-17 63.1 0.0 8.2e-16 57.8 0.0 2.7 2 0 0 2 2 2 1 HAD-hyrolase-like tRNA_anti-codon PF01336.25 KKK18605.1 - 2.8e-05 24.0 0.1 5.3e-05 23.1 0.1 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Hydrolase PF00702.26 KKK18605.1 - 0.0003 21.1 1.3 0.18 12.1 0.0 3.5 3 1 0 3 3 3 2 haloacid dehalogenase-like hydrolase eIF3_subunit PF08597.10 KKK18605.1 - 0.029 14.3 2.5 0.052 13.5 2.5 1.3 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit adh_short PF00106.25 KKK18606.1 - 3.1e-82 274.8 8.2 9.9e-44 149.1 0.4 2.5 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KKK18606.1 - 6.1e-65 219.1 2.8 7.8e-33 114.0 0.0 2.4 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase MaoC_dehydratas PF01575.19 KKK18606.1 - 1.8e-34 118.0 0.0 3.4e-34 117.1 0.0 1.4 1 0 0 1 1 1 1 MaoC like domain KR PF08659.10 KKK18606.1 - 1.4e-26 93.5 4.7 2.1e-12 47.3 0.9 2.6 2 1 0 2 2 2 2 KR domain THF_DHG_CYH_C PF02882.19 KKK18606.1 - 1.5e-06 27.6 0.1 9.9e-05 21.7 0.3 2.6 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Fungal_TACC PF12709.7 KKK18618.1 - 2.9e-12 46.8 24.1 6.8e-10 39.3 4.3 4.3 4 0 0 4 4 4 2 Fungal Transforming acidic coiled-coil (TACC) proteins DUF4407 PF14362.6 KKK18618.1 - 0.095 12.0 28.7 0.69 9.2 14.1 3.3 1 1 2 3 3 3 0 Domain of unknown function (DUF4407) ERM PF00769.19 KKK18618.1 - 0.44 10.3 50.3 0.68 9.7 20.5 4.0 2 1 2 4 4 4 0 Ezrin/radixin/moesin family FPP PF05911.11 KKK18618.1 - 0.66 8.1 32.4 0.27 9.4 9.2 2.2 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil DUF3235 PF11574.8 KKK18618.1 - 3.4 8.6 6.3 1.4 9.9 0.1 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3235) Filament PF00038.21 KKK18618.1 - 4.1 6.9 35.3 1.5 8.3 10.8 3.3 1 1 1 2 2 2 0 Intermediate filament protein ADIP PF11559.8 KKK18618.1 - 4.4 7.4 32.5 10 6.2 0.3 4.3 1 1 1 4 4 4 0 Afadin- and alpha -actinin-Binding CENP-F_leu_zip PF10473.9 KKK18618.1 - 5.9 6.9 45.6 8.2 6.4 12.1 4.2 2 2 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Tropomyosin_1 PF12718.7 KKK18618.1 - 7.5 6.7 40.1 0.99 9.6 18.5 3.8 2 1 1 3 3 3 0 Tropomyosin like MFS_1 PF07690.16 KKK18620.1 - 2.1e-30 105.9 32.7 5e-28 98.0 19.7 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KKK18620.1 - 3.1e-11 42.8 2.7 3.1e-11 42.8 2.7 1.7 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1_like PF12832.7 KKK18620.1 - 0.00014 20.9 1.3 0.00014 20.9 1.3 2.4 2 1 1 3 3 3 1 MFS_1 like family MFS_3 PF05977.13 KKK18620.1 - 0.34 9.3 8.9 0.11 10.8 3.1 2.5 2 1 0 2 2 2 0 Transmembrane secretion effector Copper-fist PF00649.18 KKK18634.1 - 7.5e-22 76.5 2.3 7.5e-22 76.5 2.3 2.0 2 0 0 2 2 2 1 Copper fist DNA binding domain Apc13p PF05839.11 KKK18636.1 - 6e-18 64.8 0.0 1.5e-17 63.5 0.0 1.7 2 0 0 2 2 2 1 Apc13p protein CBS PF00571.28 KKK18637.1 - 3.7e-22 78.5 6.1 4.8e-10 39.7 0.1 3.8 4 0 0 4 4 4 3 CBS domain CRAL_TRIO PF00650.20 KKK18638.1 - 6.1e-33 113.8 0.0 9.8e-33 113.1 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KKK18638.1 - 1.3e-15 57.3 0.1 2.5e-15 56.4 0.1 1.5 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 KKK18638.1 - 8.5e-05 22.7 0.0 0.00014 22.0 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain TraK PF06586.11 KKK18638.1 - 0.0043 16.8 1.5 0.0069 16.1 1.5 1.3 1 0 0 1 1 1 1 TraK protein Beta_protein PF14350.6 KKK18638.1 - 0.033 13.6 0.0 0.055 12.9 0.0 1.3 1 0 0 1 1 1 0 Beta protein Suc_Fer-like PF06999.12 KKK18639.1 - 1.2e-07 31.8 0.0 1.7e-07 31.4 0.0 1.1 1 0 0 1 1 1 1 Sucrase/ferredoxin-like CAP_N PF01213.19 KKK18639.1 - 3.3 7.1 5.2 4.4 6.7 5.2 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Aminotran_1_2 PF00155.21 KKK18640.1 - 1.9e-24 86.5 0.0 4.9e-24 85.2 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class I and II DUF4129 PF13559.6 KKK18641.1 - 3.1e-05 24.1 0.0 0.00011 22.3 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4129) NICE-3 PF07406.11 KKK18641.1 - 0.005 16.9 0.0 0.011 15.7 0.0 1.6 1 0 0 1 1 1 1 NICE-3 protein MASE3 PF17159.4 KKK18641.1 - 0.27 10.8 4.9 0.41 10.2 4.9 1.2 1 0 0 1 1 1 0 Membrane-associated sensor domain Ribosomal_60s PF00428.19 KKK18641.1 - 0.47 11.1 4.0 4.5 7.9 0.9 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein Fungal_trans PF04082.18 KKK18642.1 - 2.8e-22 79.0 3.7 3.5e-21 75.4 0.0 2.9 3 0 0 3 3 3 2 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK18642.1 - 0.0044 17.1 4.9 0.0074 16.4 4.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Flavin_Reduct PF01613.18 KKK18643.1 - 2.5e-17 63.3 0.0 3.5e-17 62.9 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain DUF447 PF04289.12 KKK18643.1 - 0.18 11.6 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF447) Fungal_trans_2 PF11951.8 KKK18651.1 - 3.8e-07 29.3 1.2 6.2e-07 28.6 0.3 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK18651.1 - 3e-06 27.2 9.2 6.4e-06 26.2 9.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HEAT_2 PF13646.6 KKK18651.1 - 0.014 15.8 0.0 0.03 14.7 0.0 1.5 1 0 0 1 1 1 0 HEAT repeats MFS_1 PF07690.16 KKK18652.1 - 2.3e-13 49.8 10.3 2.5e-13 49.7 9.0 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily TRP PF06011.12 KKK18654.1 - 4e-43 147.7 20.7 4.6e-35 121.2 17.8 2.1 1 1 1 2 2 2 2 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 KKK18654.1 - 8.2e-23 81.3 0.1 1.3e-22 80.7 0.1 1.3 1 0 0 1 1 1 1 ML-like domain DUF4381 PF14316.6 KKK18654.1 - 1.3 9.2 7.4 0.24 11.6 1.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) Stevor PF17410.2 KKK18654.1 - 5.9 6.3 7.7 1.9 8.0 1.2 2.2 2 0 0 2 2 2 0 Subtelomeric Variable Open Reading frame FYVE PF01363.21 KKK18655.1 - 1.8e-20 72.9 1.0 1.8e-20 72.9 1.0 3.5 4 0 0 4 4 4 1 FYVE zinc finger Zn_clus PF00172.18 KKK18655.1 - 6.1e-05 23.1 9.8 6.1e-05 23.1 9.8 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KKK18655.1 - 8.7e-05 21.7 0.0 0.00032 19.8 0.0 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain zf-RING_11 PF17123.5 KKK18655.1 - 0.11 12.3 2.4 0.15 11.8 0.2 2.4 2 0 0 2 2 2 0 RING-like zinc finger Zn-C2H2_12 PF18112.1 KKK18655.1 - 5.4 7.6 7.9 13 6.4 0.1 3.3 3 0 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain Asn_synthase PF00733.21 KKK18668.1 - 6.9e-94 315.4 0.5 1e-54 186.6 0.0 2.1 1 1 1 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 KKK18668.1 - 1.6e-35 121.7 0.0 2.6e-35 121.0 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 KKK18668.1 - 1.4e-25 90.0 0.0 2.4e-25 89.3 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 KKK18668.1 - 5e-09 35.9 0.0 1e-08 35.0 0.0 1.4 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.17 KKK18668.1 - 0.00074 18.7 0.0 0.0013 17.9 0.0 1.5 1 1 0 1 1 1 1 NAD synthase Curto_V2 PF07325.11 KKK18668.1 - 0.054 13.4 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Curtovirus V2 protein QueC PF06508.13 KKK18668.1 - 0.2 11.1 0.0 0.4 10.1 0.0 1.4 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC Porin_3 PF01459.22 KKK18669.1 - 6e-74 248.9 3.8 1.3e-59 201.9 0.9 2.1 2 0 0 2 2 2 2 Eukaryotic porin VasI PF11319.8 KKK18669.1 - 0.19 11.4 0.1 1.6 8.3 0.0 2.3 3 0 0 3 3 3 0 Type VI secretion system VasI, EvfG, VC_A0118 DnaJ PF00226.31 KKK18670.1 - 0.0019 18.3 0.0 0.003 17.6 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain RICTOR_N PF14664.6 KKK18671.1 - 1.9e-129 431.9 1.0 4.7e-129 430.6 0.4 2.0 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, N-term RasGEF_N_2 PF14663.6 KKK18671.1 - 3e-39 133.8 0.1 6.7e-36 123.0 0.0 3.4 3 0 0 3 3 3 2 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_M PF14666.6 KKK18671.1 - 4.7e-39 132.4 1.4 2.3e-34 117.3 0.1 5.1 5 0 0 5 5 5 1 Rapamycin-insensitive companion of mTOR, middle domain RICTOR_V PF14668.6 KKK18671.1 - 1e-25 89.8 4.9 2.2e-25 88.7 0.1 3.9 6 0 0 6 6 6 1 Rapamycin-insensitive companion of mTOR, domain 5 HR1 PF02185.16 KKK18671.1 - 2.3e-16 59.7 7.3 5.7e-16 58.4 7.3 1.7 1 0 0 1 1 1 1 Hr1 repeat Uds1 PF15456.6 KKK18671.1 - 0.066 13.4 5.6 0.17 12.1 5.6 1.6 1 0 0 1 1 1 0 Up-regulated During Septation Arm PF00514.23 KKK18671.1 - 0.25 11.5 3.5 14 5.9 0.1 3.3 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat CDH-cyt PF16010.5 KKK18672.1 - 7.1e-20 71.4 0.0 1.3e-19 70.6 0.0 1.3 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase Cytochrom_B561 PF03188.16 KKK18672.1 - 1.1e-06 28.9 4.6 2.2e-06 27.8 4.6 1.5 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DUF1616 PF07760.11 KKK18672.1 - 0.11 11.9 1.2 0.22 10.9 1.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1616) Phage_holin_3_6 PF07332.11 KKK18672.1 - 1.9 8.5 6.3 23 5.1 4.3 2.6 2 1 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III p450 PF00067.22 KKK18673.1 - 1.5e-63 215.1 0.0 3.1e-63 214.1 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 Kinetochor_Ybp2 PF08568.10 KKK18674.1 - 2.6e-160 535.0 0.0 3.4e-160 534.6 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin DHHC PF01529.20 KKK18676.1 - 3.1e-38 130.9 3.6 4.8e-38 130.3 3.6 1.3 1 0 0 1 1 1 1 DHHC palmitoyltransferase UQ_con PF00179.26 KKK18676.1 - 2.6e-19 69.2 0.0 6e-19 68.1 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Vma12 PF11712.8 KKK18676.1 - 1.5 8.9 6.5 23 5.1 0.2 3.4 3 0 0 3 3 3 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Rhomboid PF01694.22 KKK18677.1 - 1.2e-31 109.8 9.7 1.2e-31 109.8 9.7 1.7 2 0 0 2 2 2 1 Rhomboid family DUF1129 PF06570.11 KKK18677.1 - 3.4 7.1 5.9 11 5.4 0.9 3.2 3 1 1 4 4 4 0 Protein of unknown function (DUF1129) SPT_ssu-like PF11779.8 KKK18678.1 - 4.2e-17 61.5 2.7 5.9e-17 61.0 1.8 1.7 2 0 0 2 2 2 1 Small subunit of serine palmitoyltransferase-like Cytochrome_CBB3 PF13442.6 KKK18680.1 - 0.16 12.3 0.1 0.19 12.1 0.1 1.1 1 0 0 1 1 1 0 Cytochrome C oxidase, cbb3-type, subunit III WH1 PF00568.23 KKK18681.1 - 1.6e-29 102.1 0.0 2.4e-29 101.5 0.0 1.2 1 0 0 1 1 1 1 WH1 domain eIF-1a PF01176.19 KKK18682.1 - 4.4e-22 77.6 0.0 6.3e-22 77.2 0.0 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 ERCC4 PF02732.15 KKK18683.1 - 3.9e-14 53.1 0.0 9.2e-14 51.9 0.0 1.6 1 0 0 1 1 1 1 ERCC4 domain HHH_5 PF14520.6 KKK18683.1 - 0.0017 18.9 0.0 0.0041 17.7 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain CNOT1_HEAT PF16418.5 KKK18683.1 - 0.16 12.0 0.0 3.2 7.8 0.0 2.6 2 0 0 2 2 2 0 CCR4-NOT transcription complex subunit 1 HEAT repeat fn3_2 PF16893.5 KKK18684.1 - 2.1e-38 130.4 0.1 4.2e-38 129.4 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III domain CHS5_N PF16892.5 KKK18684.1 - 4.7e-25 87.3 0.4 8.8e-25 86.4 0.4 1.5 1 0 0 1 1 1 1 Chitin biosynthesis protein CHS5 N-terminus PTCB-BRCT PF12738.7 KKK18684.1 - 4.9e-12 45.6 0.0 8.3e-12 44.9 0.0 1.4 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.26 KKK18684.1 - 4.3e-08 33.4 0.0 7.7e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain DUF3006 PF11213.8 KKK18684.1 - 0.00015 22.0 0.0 0.00041 20.5 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3006) BRCT_2 PF16589.5 KKK18684.1 - 0.00077 19.8 0.0 0.0016 18.8 0.0 1.5 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain fn3 PF00041.21 KKK18684.1 - 0.0017 18.6 0.7 0.0075 16.6 0.0 2.3 2 1 0 2 2 2 1 Fibronectin type III domain Tetraspanin PF00335.20 KKK18718.1 - 0.00032 20.5 1.7 0.00074 19.3 1.8 1.5 1 1 1 2 2 2 1 Tetraspanin family MFS_1 PF07690.16 KKK18720.1 - 4.8e-05 22.4 5.9 6.5e-05 22.0 5.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Aminotran_3 PF00202.21 KKK18721.1 - 8.6e-39 133.3 0.2 1.5e-34 119.3 0.2 3.0 1 1 0 1 1 1 1 Aminotransferase class-III DUF4646 PF15496.6 KKK18721.1 - 0.24 12.0 0.0 0.57 10.8 0.0 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4646) FAD_binding_4 PF01565.23 KKK18722.1 - 1.2e-30 106.1 4.9 2.2e-30 105.2 4.9 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KKK18722.1 - 7e-09 35.6 0.4 1.5e-08 34.6 0.4 1.5 1 0 0 1 1 1 1 Berberine and berberine like AAA_16 PF13191.6 KKK18723.1 - 7.4e-09 36.2 1.9 3.2e-08 34.1 0.2 2.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KKK18723.1 - 1.4e-08 35.1 0.6 1.8e-07 31.5 0.1 3.1 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KKK18723.1 - 3e-07 30.5 0.7 1.5e-06 28.3 0.1 2.7 2 1 0 2 2 2 1 NACHT domain TPR_10 PF13374.6 KKK18723.1 - 1.1e-06 28.3 0.9 0.05 13.5 0.0 5.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 KKK18723.1 - 4.1e-05 23.8 17.1 0.5 10.7 0.2 8.5 10 0 0 10 10 8 2 Tetratricopeptide repeat AAA_7 PF12775.7 KKK18723.1 - 0.00024 20.7 0.0 0.00087 18.8 0.0 1.9 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_30 PF13604.6 KKK18723.1 - 0.00033 20.4 0.0 0.0012 18.6 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 KKK18723.1 - 0.0019 18.6 0.1 0.02 15.3 0.0 3.0 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) TPR_7 PF13176.6 KKK18723.1 - 0.0048 16.8 0.1 4 7.7 0.0 4.8 4 0 0 4 4 4 1 Tetratricopeptide repeat ResIII PF04851.15 KKK18723.1 - 0.011 15.8 0.4 0.09 12.8 0.0 2.8 3 0 0 3 3 2 0 Type III restriction enzyme, res subunit RuvB_N PF05496.12 KKK18723.1 - 0.037 13.8 0.2 0.17 11.6 0.0 2.2 2 0 0 2 2 1 0 Holliday junction DNA helicase RuvB P-loop domain ATPase_2 PF01637.18 KKK18723.1 - 0.044 13.7 0.4 0.44 10.4 0.0 2.8 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea TPR_2 PF07719.17 KKK18723.1 - 0.045 13.9 7.3 62 4.1 0.1 6.7 8 0 0 8 8 6 0 Tetratricopeptide repeat ABC_tran PF00005.27 KKK18723.1 - 0.05 14.1 0.4 1.8 9.1 0.0 3.5 2 0 0 2 2 2 0 ABC transporter IstB_IS21 PF01695.17 KKK18723.1 - 0.056 13.2 1.0 0.3 10.8 0.0 2.8 3 0 0 3 3 3 0 IstB-like ATP binding protein Mg_chelatase PF01078.21 KKK18723.1 - 0.062 12.7 0.0 0.16 11.3 0.0 1.7 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_11 PF13086.6 KKK18723.1 - 0.14 11.9 0.0 0.14 11.9 0.0 3.6 3 0 0 3 3 3 0 AAA domain AAA_5 PF07728.14 KKK18723.1 - 0.17 11.9 0.9 1.9 8.5 0.0 2.9 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) FadR_C PF07840.12 KKK18723.1 - 0.41 10.5 7.1 1.8 8.5 0.1 4.5 4 0 0 4 4 4 0 FadR C-terminal domain AAA_19 PF13245.6 KKK18723.1 - 4.6 7.6 10.4 0.52 10.6 0.0 3.4 3 0 0 3 3 3 0 AAA domain SET PF00856.28 KKK18724.1 - 6.4e-12 46.2 0.0 1.2e-11 45.3 0.0 1.4 1 1 0 1 1 1 1 SET domain Methyltransf_25 PF13649.6 KKK18725.1 - 2.1e-16 60.4 0.0 3.6e-16 59.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KKK18725.1 - 1.4e-14 54.2 0.0 1.9e-14 53.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KKK18725.1 - 4.6e-12 46.4 0.0 7.6e-12 45.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KKK18725.1 - 1.6e-11 44.3 0.0 2.1e-11 43.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KKK18725.1 - 3.8e-09 37.2 0.0 5.9e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KKK18725.1 - 4.8e-06 26.2 0.0 6.7e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain TehB PF03848.14 KKK18725.1 - 3.5e-05 23.3 0.0 5.3e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB FtsJ PF01728.19 KKK18725.1 - 7e-05 23.0 0.0 9e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase CheR PF01739.18 KKK18725.1 - 0.00026 20.5 0.0 0.035 13.6 0.0 2.1 1 1 1 2 2 2 1 CheR methyltransferase, SAM binding domain Methyltransf_2 PF00891.18 KKK18725.1 - 0.00031 20.1 0.0 0.00043 19.6 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_32 PF13679.6 KKK18725.1 - 0.0013 18.7 0.0 0.0022 18.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.11 KKK18725.1 - 0.0014 18.3 0.0 0.0024 17.5 0.0 1.4 1 1 0 1 1 1 1 Nodulation protein S (NodS) PCMT PF01135.19 KKK18725.1 - 0.011 15.5 0.0 0.02 14.7 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.20 KKK18725.1 - 0.021 14.1 0.0 0.026 13.8 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_5 PF01795.19 KKK18725.1 - 0.097 12.2 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 MraW methylase family Methyltransf_4 PF02390.17 KKK18725.1 - 0.15 11.5 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase GMC_oxred_C PF05199.13 KKK18726.1 - 2.6e-38 131.8 0.0 3.5e-38 131.3 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 KKK18726.1 - 1.8e-10 40.7 0.1 2.5e-10 40.2 0.1 1.2 1 0 0 1 1 1 1 GMC oxidoreductase Catalase_C PF18011.1 KKK18726.1 - 0.21 11.2 0.0 0.37 10.4 0.0 1.3 1 0 0 1 1 1 0 C-terminal domain found in long catalases CN_hydrolase PF00795.22 KKK18727.1 - 1.7e-35 122.6 0.0 2.8e-35 121.9 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase GST_N_3 PF13417.6 KKK18728.1 - 1.2e-05 25.7 0.0 2.8e-05 24.4 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KKK18728.1 - 0.0009 19.5 0.0 0.0031 17.8 0.0 1.9 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_6 PF17171.4 KKK18728.1 - 0.15 11.8 0.0 0.39 10.5 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DUF455 PF04305.14 KKK18729.1 - 2.2e-98 328.7 0.0 2.8e-98 328.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF455) Rieske PF00355.26 KKK18729.1 - 4.4e-06 26.5 0.0 1e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 KKK18729.1 - 0.0022 17.9 0.0 0.009 15.9 0.0 2.1 2 1 0 2 2 2 1 Rieske-like [2Fe-2S] domain FAD_binding_3 PF01494.19 KKK18730.1 - 5.8e-23 81.7 0.0 7.9e-22 78.0 0.0 2.2 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KKK18730.1 - 1.5e-06 27.7 0.1 0.0095 15.2 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KKK18730.1 - 5.2e-05 23.7 1.7 0.00037 21.0 0.1 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KKK18730.1 - 0.00012 22.2 0.1 0.0003 21.0 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KKK18730.1 - 0.0007 19.3 0.2 0.011 15.4 0.1 2.1 1 1 1 2 2 2 1 FAD dependent oxidoreductase SE PF08491.10 KKK18730.1 - 0.00085 18.5 0.0 0.003 16.6 0.0 1.8 2 0 0 2 2 2 1 Squalene epoxidase Amino_oxidase PF01593.24 KKK18730.1 - 0.0064 15.8 0.0 0.064 12.5 0.0 2.0 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.6 KKK18730.1 - 0.052 12.8 0.1 1.6 7.9 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KKK18730.1 - 0.14 11.0 0.3 4.8 5.9 0.1 2.2 2 0 0 2 2 2 0 Tryptophan halogenase Cnd3 PF12719.7 KKK18737.1 - 1e-83 280.9 0.2 1.6e-82 277.0 0.0 2.6 2 1 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.6 KKK18737.1 - 5e-09 36.4 7.2 2.2e-05 24.7 1.9 3.9 2 1 2 4 4 4 3 HEAT repeats HEAT_EZ PF13513.6 KKK18737.1 - 5.2e-07 30.0 1.1 0.076 13.5 0.1 4.3 3 0 0 3 3 3 2 HEAT-like repeat HEAT PF02985.22 KKK18737.1 - 2.6e-05 24.1 11.5 0.063 13.6 0.0 6.8 7 1 1 8 8 8 2 HEAT repeat Cnd1 PF12717.7 KKK18737.1 - 0.01 15.9 0.0 0.12 12.4 0.0 2.7 2 1 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 zf-RanBP PF00641.18 KKK18738.1 - 1.2e-20 72.5 9.1 7.7e-11 41.1 1.5 2.4 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others RRM_1 PF00076.22 KKK18738.1 - 7.7e-08 32.1 0.0 1.9e-07 30.8 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNase_T PF00929.24 KKK18738.1 - 9.7e-07 29.5 0.0 1.5e-06 28.9 0.0 1.3 1 0 0 1 1 1 1 Exonuclease zf-ribbon_3 PF13248.6 KKK18738.1 - 0.2 11.1 2.4 2.5 7.6 0.3 2.8 2 0 0 2 2 2 0 zinc-ribbon domain DZR PF12773.7 KKK18738.1 - 0.26 11.3 4.0 2.4 8.3 0.2 2.4 2 0 0 2 2 2 0 Double zinc ribbon MFS_1 PF07690.16 KKK18739.1 - 8e-53 179.6 35.0 3.3e-49 167.7 20.1 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KKK18739.1 - 8.3e-07 27.7 0.7 0.0048 15.2 1.5 2.7 2 1 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family MFS_2 PF13347.6 KKK18739.1 - 0.001 17.7 16.8 0.018 13.6 8.7 2.6 2 1 0 2 2 2 2 MFS/sugar transport protein MFS_1_like PF12832.7 KKK18739.1 - 0.078 11.8 13.4 0.12 11.2 7.4 2.9 1 1 1 3 3 3 0 MFS_1 like family Trp_oprn_chp PF09534.10 KKK18739.1 - 0.46 10.3 15.1 0.37 10.6 5.0 2.7 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DIOX_N PF14226.6 KKK18740.1 - 9.1e-16 58.7 0.0 1.7e-15 57.8 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KKK18740.1 - 4.2e-15 56.1 0.0 9.4e-15 54.9 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily AMP-binding PF00501.28 KKK18741.1 - 1.7e-53 181.7 0.0 2.4e-53 181.3 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 KKK18741.1 - 1.7e-28 99.5 0.0 5.3e-28 97.9 0.0 1.7 2 0 0 2 2 2 1 Condensation domain PP-binding PF00550.25 KKK18741.1 - 2.8e-07 30.8 0.1 6.4e-07 29.6 0.1 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KKK18741.1 - 0.01 16.8 0.0 0.051 14.6 0.0 2.3 2 0 0 2 2 2 0 AMP-binding enzyme C-terminal domain PS_Dcarbxylase PF02666.15 KKK18742.1 - 1.9e-37 128.8 0.0 2.6e-37 128.3 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase PSDC PF12588.8 KKK18742.1 - 2e-35 121.8 0.1 4.1e-35 120.8 0.1 1.5 1 0 0 1 1 1 1 Phophatidylserine decarboxylase RnfC_N PF13375.6 KKK18742.1 - 0.0053 16.7 0.0 1.4 9.0 0.0 2.9 3 0 0 3 3 3 2 RnfC Barrel sandwich hybrid domain Lipase3_N PF03893.16 KKK18743.1 - 5.4e-07 29.5 1.2 2e-06 27.7 0.1 2.0 2 0 0 2 2 2 1 Lipase 3 N-terminal region HECA PF15353.6 KKK18743.1 - 0.016 15.5 0.0 0.031 14.5 0.0 1.4 1 0 0 1 1 1 0 Headcase protein family homologue ApoL PF05461.11 KKK18743.1 - 0.14 11.4 0.2 0.18 11.1 0.2 1.1 1 0 0 1 1 1 0 Apolipoprotein L DUF3431 PF11913.8 KKK18744.1 - 3.7e-89 298.1 0.4 6.1e-89 297.4 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) Peptidase_M16_M PF16187.5 KKK18745.1 - 1.5e-96 323.0 0.1 3e-96 322.0 0.1 1.5 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 Peptidase_M16_C PF05193.21 KKK18745.1 - 6.4e-34 117.6 0.2 2e-23 83.4 0.0 3.8 5 1 1 6 6 6 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 KKK18745.1 - 1.8e-32 112.4 3.8 3.5e-23 82.2 0.4 3.7 3 1 1 4 4 4 2 Insulinase (Peptidase family M16) ERCC4 PF02732.15 KKK18745.1 - 0.017 15.3 0.1 0.063 13.5 0.0 2.0 2 0 0 2 2 2 0 ERCC4 domain NUDIX_2 PF13869.6 KKK18746.1 - 3.9e-73 245.1 0.1 9.7e-72 240.5 0.1 2.0 1 1 0 1 1 1 1 Nucleotide hydrolase Arb2 PF09757.9 KKK18747.1 - 1.8e-105 351.8 0.2 2.3e-105 351.4 0.2 1.1 1 0 0 1 1 1 1 Arb2 domain Hist_deacetyl PF00850.19 KKK18747.1 - 5.2e-85 285.6 0.0 7.8e-85 285.0 0.0 1.3 1 0 0 1 1 1 1 Histone deacetylase domain Bys1 PF04681.12 KKK18748.1 - 3.1e-11 43.4 0.4 3.7e-11 43.2 0.4 1.0 1 0 0 1 1 1 1 Blastomyces yeast-phase-specific protein zf-CHCC PF10276.9 KKK18749.1 - 1.1e-15 57.3 2.0 1.8e-15 56.7 2.0 1.3 1 0 0 1 1 1 1 Zinc-finger domain MPP6 PF10175.9 KKK18750.1 - 4.9e-05 23.8 8.4 0.0002 21.9 8.4 1.9 1 1 0 1 1 1 1 M-phase phosphoprotein 6 F-box-like PF12937.7 KKK18751.1 - 1.2e-08 34.7 0.1 3.4e-08 33.2 0.1 1.9 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KKK18751.1 - 0.05 14.0 0.4 0.56 10.7 0.6 2.6 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) F-box PF00646.33 KKK18751.1 - 0.1 12.5 0.4 3.7 7.5 0.2 2.7 2 0 0 2 2 2 0 F-box domain F-box_5 PF18511.1 KKK18751.1 - 0.12 12.0 0.1 0.84 9.3 0.2 2.1 2 0 0 2 2 2 0 F-box UPF0047 PF01894.17 KKK18752.1 - 4.5e-37 126.7 0.0 5.1e-37 126.5 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 PQQ_2 PF13360.6 KKK18753.1 - 0.038 13.6 0.1 0.99 8.9 0.1 2.4 1 1 0 1 1 1 0 PQQ-like domain Ldh_2 PF02615.14 KKK18753.1 - 0.074 12.2 0.1 0.12 11.5 0.1 1.2 1 0 0 1 1 1 0 Malate/L-lactate dehydrogenase BTB PF00651.31 KKK18754.1 - 9.8e-07 29.0 1.2 2.1e-06 27.9 0.3 1.9 2 0 0 2 2 2 1 BTB/POZ domain Proteasome PF00227.26 KKK18755.1 - 5.4e-56 189.1 0.1 7.6e-56 188.6 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KKK18755.1 - 8.5e-14 50.9 0.3 3e-13 49.1 0.1 2.0 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Terminase_5 PF06056.12 KKK18755.1 - 0.025 14.5 0.1 0.053 13.4 0.1 1.5 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) DUF4707 PF15806.5 KKK18755.1 - 0.11 11.4 0.0 0.19 10.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4707) zf-CHY PF05495.12 KKK18756.1 - 7.2e-09 36.0 17.5 3.9e-06 27.3 11.5 2.4 2 0 0 2 2 2 2 CHY zinc finger RNA_POL_M_15KD PF02150.16 KKK18756.1 - 0.043 13.7 7.8 5.7 6.9 0.2 3.4 2 1 1 3 3 3 0 RNA polymerases M/15 Kd subunit Zn_Tnp_IS1595 PF12760.7 KKK18756.1 - 0.13 12.3 11.8 0.74 9.8 0.5 3.3 2 1 1 3 3 3 0 Transposase zinc-ribbon domain BAP PF06639.11 KKK18756.1 - 0.17 12.2 3.2 5.2 7.5 0.2 2.3 1 1 1 2 2 2 0 Basal layer antifungal peptide (BAP) C1_4 PF07975.12 KKK18756.1 - 0.44 10.8 12.2 4.4 7.6 0.5 2.9 1 1 2 3 3 3 0 TFIIH C1-like domain zinc_ribbon_10 PF10058.9 KKK18756.1 - 0.49 10.1 6.9 0.67 9.7 3.2 2.3 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein zinc_ribbon_9 PF14369.6 KKK18756.1 - 0.73 10.1 9.5 1 9.7 6.4 2.6 1 1 1 2 2 2 0 zinc-ribbon HypA PF01155.19 KKK18756.1 - 1.9 8.5 10.1 12 5.9 10.2 2.1 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_4 PF13717.6 KKK18756.1 - 2.2 8.3 13.0 3.4 7.7 1.5 3.6 4 0 0 4 4 4 0 zinc-ribbon domain Zn-ribbon_8 PF09723.10 KKK18756.1 - 2.4 8.3 16.8 2.6 8.2 9.1 2.4 1 1 1 2 2 2 0 Zinc ribbon domain zinc_ribbon_5 PF13719.6 KKK18756.1 - 8.2 6.3 12.7 26 4.7 6.7 3.4 2 1 1 3 3 3 0 zinc-ribbon domain CoaE PF01121.20 KKK18758.1 - 3.2e-40 137.7 0.0 5.7e-40 136.9 0.0 1.4 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_18 PF13238.6 KKK18758.1 - 0.0076 16.8 0.2 0.32 11.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain ATG13 PF10033.9 KKK18763.1 - 1.8e-72 243.9 0.0 2.6e-72 243.4 0.0 1.2 1 0 0 1 1 1 1 Autophagy-related protein 13 HEAT_2 PF13646.6 KKK18789.1 - 1.8e-30 105.2 0.2 3.5e-14 52.9 0.1 3.4 2 2 2 4 4 4 3 HEAT repeats HEAT_PBS PF03130.16 KKK18789.1 - 7.7e-20 69.5 0.1 0.028 15.1 0.0 6.8 7 0 0 7 7 7 5 PBS lyase HEAT-like repeat HEAT PF02985.22 KKK18789.1 - 2.5e-08 33.5 1.6 2.5 8.6 0.0 6.6 7 0 0 7 7 7 1 HEAT repeat Cnd1 PF12717.7 KKK18789.1 - 0.003 17.6 0.0 6.6 6.8 0.0 3.2 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 KKK18789.1 - 0.0042 17.6 6.5 8.7 7.0 0.0 5.3 4 3 3 7 7 7 1 HEAT-like repeat Cohesin_HEAT PF12765.7 KKK18789.1 - 0.031 14.6 0.0 0.57 10.5 0.0 2.7 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion PUB_1 PF18486.1 KKK18789.1 - 0.1 12.5 0.7 0.48 10.3 0.2 2.4 2 0 0 2 2 2 0 PNGase/UBA- or UBX-containing domain RuvA_C PF07499.13 KKK18789.1 - 0.11 12.9 2.1 6.6 7.3 0.1 3.1 3 0 0 3 3 3 0 RuvA, C-terminal domain Pkinase PF00069.25 KKK18790.1 - 5.6e-07 29.2 0.0 1.9e-06 27.5 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Nipped-B_C PF12830.7 KKK18791.1 - 1.8e-46 158.5 5.3 5.4e-45 153.7 0.5 3.6 3 1 0 3 3 3 2 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.7 KKK18791.1 - 5.6e-12 45.7 3.7 7.9e-12 45.2 1.6 2.5 2 0 0 2 2 2 1 HEAT repeat associated with sister chromatid cohesion Adaptin_N PF01602.20 KKK18791.1 - 6.2e-05 21.7 0.9 0.0011 17.6 0.5 3.0 2 1 0 2 2 2 1 Adaptin N terminal region Cnd3 PF12719.7 KKK18791.1 - 0.00013 21.3 3.6 0.21 10.7 0.0 3.4 3 1 0 3 3 3 2 Nuclear condensing complex subunits, C-term domain Cnd1 PF12717.7 KKK18791.1 - 0.00092 19.3 4.4 0.028 14.5 0.1 3.2 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KKK18791.1 - 0.002 18.2 3.8 0.74 10.2 0.4 5.2 4 0 0 4 4 4 1 HEAT repeat HEAT_2 PF13646.6 KKK18791.1 - 0.013 15.9 0.7 2.6 8.5 0.2 4.1 4 0 0 4 4 4 0 HEAT repeats Xpo1 PF08389.12 KKK18791.1 - 0.016 15.3 0.1 1.8 8.6 0.0 3.5 3 0 0 3 3 3 0 Exportin 1-like protein Pyr_redox_2 PF07992.14 KKK18792.1 - 1.2e-43 149.4 0.0 1.6e-43 149.0 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KKK18792.1 - 3.7e-11 43.4 0.0 1.5e-09 38.3 0.0 2.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase EF-hand_1 PF00036.32 KKK18792.1 - 5.8e-07 28.6 0.1 1.8e-06 27.1 0.1 1.9 2 0 0 2 2 2 1 EF hand EF-hand_5 PF13202.6 KKK18792.1 - 1.1e-05 24.7 0.3 2.3e-05 23.7 0.3 1.5 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 KKK18792.1 - 1.8e-05 24.3 0.3 5.3e-05 22.8 0.3 1.8 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 KKK18792.1 - 2.4e-05 24.7 0.0 7.1e-05 23.2 0.0 1.8 1 0 0 1 1 1 1 EF-hand domain pair Pyr_redox_3 PF13738.6 KKK18792.1 - 0.13 11.5 1.3 3.6 6.8 1.3 2.2 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TFIIS_C PF01096.18 KKK18793.1 - 5.3e-15 55.0 9.6 1.8e-14 53.3 2.7 3.1 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 KKK18793.1 - 0.0011 18.8 0.2 0.0011 18.8 0.2 2.8 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit TF_Zn_Ribbon PF08271.12 KKK18793.1 - 0.01 15.3 4.5 1.1 8.8 0.1 3.4 3 0 0 3 3 3 0 TFIIB zinc-binding Zn-ribbon_8 PF09723.10 KKK18793.1 - 0.024 14.8 2.5 3 8.0 0.3 2.6 2 1 0 2 2 2 0 Zinc ribbon domain DZR PF12773.7 KKK18793.1 - 0.033 14.2 6.3 1.8 8.6 6.3 2.5 1 1 0 1 1 1 0 Double zinc ribbon zf-IS66 PF13005.7 KKK18793.1 - 0.095 13.1 2.7 33 5.0 0.1 3.3 3 0 0 3 3 3 0 zinc-finger binding domain of transposase IS66 Lar_restr_allev PF14354.6 KKK18793.1 - 0.12 12.8 5.9 10 6.6 0.6 3.2 2 1 1 3 3 3 0 Restriction alleviation protein Lar Nudix_N_2 PF14803.6 KKK18793.1 - 0.19 11.6 6.3 0.31 11.0 2.2 2.7 2 1 0 2 2 2 0 Nudix N-terminal zinc_ribbon_2 PF13240.6 KKK18793.1 - 0.42 10.4 10.8 6.7 6.6 0.0 3.6 4 0 0 4 4 4 0 zinc-ribbon domain zf-ribbon_3 PF13248.6 KKK18793.1 - 0.72 9.3 9.1 14 5.2 0.0 3.6 4 0 0 4 4 4 0 zinc-ribbon domain OrfB_Zn_ribbon PF07282.11 KKK18793.1 - 4.5 7.3 6.5 5.1 7.1 0.2 2.6 2 2 0 2 2 2 0 Putative transposase DNA-binding domain Glyco_transf_34 PF05637.12 KKK18795.1 - 1.3e-17 64.3 0.0 3.7e-10 39.9 0.0 2.2 1 1 1 2 2 2 2 galactosyl transferase GMA12/MNN10 family DUF273 PF03314.14 KKK18795.1 - 0.042 13.4 0.0 0.061 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF273 Pkinase_Tyr PF07714.17 KKK18796.1 - 2.2e-21 76.3 0.0 5.4e-21 75.0 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KKK18796.1 - 8.3e-21 74.5 0.0 1.5e-20 73.7 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain RIO1 PF01163.22 KKK18796.1 - 0.0015 18.2 0.0 0.033 13.8 0.0 2.0 2 0 0 2 2 2 1 RIO1 family PLD_C PF12357.8 KKK18796.1 - 0.0027 17.6 0.0 0.027 14.4 0.0 2.1 2 0 0 2 2 2 1 Phospholipase D C terminal Kdo PF06293.14 KKK18796.1 - 0.01 15.2 0.2 0.017 14.5 0.2 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Dak1 PF02733.17 KKK18797.1 - 3.2e-100 335.1 0.0 4.3e-100 334.6 0.0 1.2 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 KKK18797.1 - 1.4e-40 139.0 0.8 2.2e-40 138.4 0.8 1.3 1 0 0 1 1 1 1 DAK2 domain Abhydrolase_3 PF07859.13 KKK18798.1 - 9e-50 169.5 0.0 1.2e-49 169.1 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KKK18798.1 - 3.7e-07 29.4 0.0 1.2e-06 27.7 0.0 1.6 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_6 PF12697.7 KKK18798.1 - 0.0033 18.1 0.4 0.0055 17.3 0.4 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Say1_Mug180 PF10340.9 KKK18798.1 - 0.12 11.2 0.0 0.22 10.4 0.0 1.3 1 1 0 1 1 1 0 Steryl acetyl hydrolase Esterase_phd PF10503.9 KKK18798.1 - 0.12 11.8 0.2 6.6 6.2 0.0 2.2 2 0 0 2 2 2 0 Esterase PHB depolymerase AA_permease_2 PF13520.6 KKK18799.1 - 3.8e-26 91.9 42.6 4.5e-26 91.7 42.6 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KKK18799.1 - 4.3e-09 35.5 33.3 5.4e-09 35.2 33.3 1.1 1 0 0 1 1 1 1 Amino acid permease Cupin_2 PF07883.11 KKK18800.1 - 0.0012 18.5 0.3 0.085 12.6 0.1 2.3 2 0 0 2 2 2 2 Cupin domain MannoseP_isomer PF01050.18 KKK18800.1 - 0.1 12.5 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Mannose-6-phosphate isomerase COesterase PF00135.28 KKK18801.1 - 5.2e-42 144.4 0.0 7.7e-38 130.6 0.0 2.1 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 KKK18801.1 - 1.7e-09 37.8 0.3 5.5e-09 36.2 0.3 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold ADH_N PF08240.12 KKK18801.1 - 3.3e-05 23.7 0.0 8.7e-05 22.4 0.0 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KKK18801.1 - 7.8e-05 22.7 0.0 0.00021 21.3 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase zf-PARP PF00645.18 KKK18802.1 - 1.4e-23 83.6 0.1 4.1e-23 82.0 0.1 1.8 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region MCM PF00493.23 KKK18802.1 - 0.1 11.7 0.1 0.15 11.1 0.1 1.2 1 0 0 1 1 1 0 MCM P-loop domain FMO-like PF00743.19 KKK18803.1 - 5.2e-10 38.4 0.0 6e-09 34.9 0.0 2.3 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 KKK18803.1 - 2.7e-07 30.7 0.0 7.3e-07 29.3 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KKK18803.1 - 2.7e-06 26.9 0.0 2.4e-05 23.8 0.0 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KKK18803.1 - 0.00033 20.7 0.0 0.0014 18.6 0.0 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 KKK18803.1 - 0.018 14.3 0.0 4.7 6.3 0.0 2.6 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KKK18803.1 - 0.022 13.9 0.0 0.081 12.0 0.0 1.9 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) 2-Hacid_dh_C PF02826.19 KKK18803.1 - 0.17 11.3 0.0 0.31 10.4 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF1168 PF06658.12 KKK18804.1 - 2.4e-39 134.3 12.1 3.2e-39 133.8 12.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) Lyase_catalyt PF09093.11 KKK18804.1 - 0.059 12.5 0.0 0.086 12.0 0.0 1.1 1 0 0 1 1 1 0 Lyase, catalytic PPL5 PF18168.1 KKK18804.1 - 0.54 9.5 4.2 0.72 9.1 4.2 1.1 1 0 0 1 1 1 0 Prim-pol family 5 RR_TM4-6 PF06459.12 KKK18804.1 - 1.6 8.5 6.9 2.2 8.1 6.9 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 NPR3 PF03666.13 KKK18804.1 - 7.7 5.2 14.4 10 4.8 14.4 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 CDC45 PF02724.14 KKK18804.1 - 8.1 4.6 11.6 9.9 4.3 11.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Peptidase_S49_N PF08496.10 KKK18804.1 - 8.2 6.5 6.4 12 6.0 6.4 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Presenilin PF01080.17 KKK18804.1 - 8.3 5.0 7.9 10 4.7 7.9 1.1 1 0 0 1 1 1 0 Presenilin Cpn60_TCP1 PF00118.24 KKK18805.1 - 6.6e-175 582.4 0.3 7.5e-175 582.3 0.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family His_Phos_1 PF00300.22 KKK18805.1 - 0.12 12.0 0.0 10 5.8 0.0 2.3 2 0 0 2 2 2 0 Histidine phosphatase superfamily (branch 1) UQ_con PF00179.26 KKK18806.1 - 5.4e-23 81.2 0.0 9.1e-23 80.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme SH3_15 PF18346.1 KKK18806.1 - 0.015 15.6 0.0 17 5.8 0.0 3.5 4 0 0 4 4 4 0 Mind bomb SH3 repeat domain FAM104 PF15434.6 KKK18806.1 - 0.65 10.6 2.5 7.7 7.1 0.2 2.4 2 0 0 2 2 2 0 Family 104 NMDAR2_C PF10565.9 KKK18807.1 - 0.073 12.0 0.4 0.082 11.8 0.4 1.0 1 0 0 1 1 1 0 N-methyl D-aspartate receptor 2B3 C-terminus DUF3435 PF11917.8 KKK18808.1 - 1.8e-11 43.7 0.0 2.3e-11 43.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) bZIP_1 PF00170.21 KKK18809.1 - 3.5e-10 39.8 15.8 5.6e-10 39.2 13.7 2.0 1 1 1 2 2 2 2 bZIP transcription factor bZIP_2 PF07716.15 KKK18809.1 - 2.7e-06 27.3 17.2 0.00012 22.0 11.7 2.3 1 1 1 2 2 2 2 Basic region leucine zipper KASH_CCD PF14662.6 KKK18809.1 - 0.00048 20.0 3.4 0.00048 20.0 3.4 1.6 1 1 1 2 2 2 2 Coiled-coil region of CCDC155 or KASH Phlebovirus_NSM PF07246.11 KKK18809.1 - 0.00049 19.6 3.2 0.00067 19.1 3.2 1.1 1 0 0 1 1 1 1 Phlebovirus nonstructural protein NS-M DUF812 PF05667.11 KKK18809.1 - 0.00061 18.8 3.1 0.00073 18.5 3.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF812) YabA PF06156.13 KKK18809.1 - 0.0015 19.1 1.2 0.0015 19.1 1.2 1.8 1 1 1 2 2 2 1 Initiation control protein YabA PTRF_SDPR PF15237.6 KKK18809.1 - 0.0055 16.4 5.2 0.0055 16.4 5.2 1.7 1 1 1 2 2 2 1 PTRF/SDPR family DUF4799 PF16056.5 KKK18809.1 - 0.0094 15.2 0.8 0.012 14.8 0.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4799) Jnk-SapK_ap_N PF09744.9 KKK18809.1 - 0.015 15.5 12.1 0.023 15.0 12.1 1.2 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 ZapB PF06005.12 KKK18809.1 - 0.022 15.2 6.9 0.022 15.2 6.9 2.1 2 1 1 3 3 3 0 Cell division protein ZapB NTP_transf_6 PF06042.11 KKK18809.1 - 0.11 12.4 1.2 0.6 10.0 0.1 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase DivIC PF04977.15 KKK18809.1 - 0.23 11.3 0.1 0.23 11.3 0.1 2.3 1 1 1 2 2 2 0 Septum formation initiator DUF4407 PF14362.6 KKK18809.1 - 0.25 10.7 1.6 0.3 10.4 1.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) bZIP_Maf PF03131.17 KKK18809.1 - 0.26 11.8 15.8 0.13 12.8 13.7 1.6 1 1 0 1 1 1 0 bZIP Maf transcription factor Cnn_1N PF07989.11 KKK18809.1 - 0.46 10.7 9.1 0.23 11.7 3.1 2.3 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 Abhydrolase_6 PF12697.7 KKK18810.1 - 3.9e-15 57.1 2.9 1.3e-14 55.4 2.1 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KKK18810.1 - 4.1e-15 56.1 0.1 8e-14 51.9 0.1 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KKK18810.1 - 5.7e-11 42.2 0.0 2e-10 40.4 0.0 1.9 2 1 0 2 2 2 1 Serine aminopeptidase, S33 DSPc PF00782.20 KKK18810.1 - 1.9e-09 37.5 0.0 4.7e-09 36.2 0.0 1.6 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Ser_hydrolase PF06821.13 KKK18810.1 - 0.00097 19.0 0.0 0.0035 17.2 0.0 1.8 2 0 0 2 2 2 1 Serine hydrolase PTPlike_phytase PF14566.6 KKK18810.1 - 0.0015 18.7 0.0 0.0026 17.9 0.0 1.3 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.27 KKK18810.1 - 0.0015 18.1 0.0 0.0047 16.5 0.0 1.7 2 0 0 2 2 2 1 Protein-tyrosine phosphatase Thioesterase PF00975.20 KKK18810.1 - 0.0021 18.2 0.1 0.0037 17.4 0.1 1.3 1 0 0 1 1 1 1 Thioesterase domain FSH1 PF03959.13 KKK18810.1 - 0.024 14.3 0.0 0.34 10.5 0.0 2.2 1 1 0 1 1 1 0 Serine hydrolase (FSH1) PGAP1 PF07819.13 KKK18810.1 - 0.13 11.9 0.0 4.2 7.0 0.0 2.3 2 0 0 2 2 2 0 PGAP1-like protein Ribosomal_S19e PF01090.19 KKK18811.1 - 7.6e-59 197.3 0.2 8.6e-59 197.2 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e Pex2_Pex12 PF04757.14 KKK18813.1 - 2.9e-37 128.4 1.2 4.1e-37 127.9 1.2 1.2 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_4 PF15227.6 KKK18813.1 - 0.0014 18.7 4.8 0.0031 17.6 4.8 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 KKK18813.1 - 0.023 14.7 1.4 0.066 13.2 1.4 1.8 1 1 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KKK18813.1 - 0.095 12.6 1.6 0.84 9.5 0.4 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Ldh_2 PF02615.14 KKK18814.1 - 3.7e-124 414.2 0.0 4.2e-124 414.0 0.0 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase Latrotoxin_C PF15658.6 KKK18814.1 - 0.023 14.5 0.0 0.036 13.8 0.0 1.4 1 0 0 1 1 1 0 Latrotoxin C-terminal domain ILVD_EDD PF00920.21 KKK18815.1 - 3.7e-210 698.9 0.8 4.4e-210 698.7 0.8 1.0 1 0 0 1 1 1 1 Dehydratase family MDM31_MDM32 PF08118.11 KKK18820.1 - 1e-253 842.8 0.0 2e-253 841.8 0.0 1.5 1 1 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins DUF3450 PF11932.8 KKK18821.1 - 0.043 13.1 1.3 0.084 12.2 1.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Nitroreductase PF00881.24 KKK18821.1 - 0.079 13.0 0.1 0.17 11.9 0.1 1.5 1 0 0 1 1 1 0 Nitroreductase family RhoGAP PF00620.27 KKK18822.1 - 3.4e-42 143.8 0.1 7e-42 142.8 0.1 1.5 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.29 KKK18822.1 - 6.7e-16 58.7 0.0 2.1e-15 57.1 0.0 1.8 2 0 0 2 2 2 1 PH domain PH_11 PF15413.6 KKK18822.1 - 8.7e-05 22.9 0.0 0.0002 21.7 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 KKK18822.1 - 0.012 15.9 0.0 0.13 12.5 0.0 2.5 2 0 0 2 2 2 0 Pleckstrin homology domain PX PF00787.24 KKK18822.1 - 0.12 12.3 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 PX domain Proteasome PF00227.26 KKK18823.1 - 2.4e-27 95.7 0.0 2.9e-27 95.4 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit HCNGP PF07818.13 KKK18824.1 - 3.3e-29 101.4 0.4 6.5e-29 100.4 0.4 1.5 1 0 0 1 1 1 1 HCNGP-like protein Proteasome PF00227.26 KKK18825.1 - 1.5e-33 115.9 0.0 8.9e-33 113.4 0.1 1.9 2 0 0 2 2 2 1 Proteasome subunit DUF974 PF06159.13 KKK18825.1 - 0.2 11.4 0.0 0.27 11.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF974) KH_8 PF17903.1 KKK18826.1 - 1.5e-05 25.0 0.0 2.9e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 KKK18826.1 - 0.0014 18.4 1.8 0.0037 17.1 1.8 1.7 1 0 0 1 1 1 1 KH domain Lipase_3 PF01764.25 KKK18827.1 - 3.5e-30 104.8 0.0 5.6e-30 104.1 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) WD40 PF00400.32 KKK18827.1 - 1.7e-13 50.8 7.6 0.00073 20.3 0.0 6.1 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKK18827.1 - 5.6e-05 23.4 0.0 0.11 12.7 0.0 4.2 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Abhydrolase_6 PF12697.7 KKK18827.1 - 0.00031 21.4 0.1 0.0007 20.3 0.1 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KKK18827.1 - 0.00075 18.8 0.0 0.0014 18.0 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 KKK18827.1 - 0.004 16.9 0.0 0.0078 16.0 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Esterase PF00756.20 KKK18827.1 - 0.0088 15.7 0.0 0.016 14.8 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Autophagy_act_C PF03987.15 KKK18828.1 - 1.6e-13 51.0 0.2 3e-13 50.1 0.2 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain RRM_1 PF00076.22 KKK18829.1 - 4.2e-09 36.1 0.0 9.4e-09 35.0 0.0 1.6 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KKK18829.1 - 4.9e-05 22.9 0.0 6.6e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KKK18829.1 - 0.098 12.5 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Occluded RNA-recognition motif FAA_hydrolase PF01557.18 KKK18830.1 - 4.2e-64 216.2 0.0 5.2e-64 215.9 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family GspH PF12019.8 KKK18830.1 - 0.02 15.3 0.2 0.034 14.6 0.2 1.3 1 0 0 1 1 1 0 Type II transport protein GspH HSP20 PF00011.21 KKK18831.1 - 1.5e-16 60.4 1.2 9.9e-13 48.1 0.1 2.3 2 0 0 2 2 2 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KKK18831.1 - 1.6e-06 27.5 0.0 0.0025 17.3 0.0 2.2 2 0 0 2 2 2 2 HSP20-like domain found in ArsA SURF2 PF05477.11 KKK18831.1 - 0.043 13.5 3.0 0.052 13.2 3.0 1.1 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) Glyco_hydro_7 PF00840.20 KKK18832.1 - 5.4e-149 496.6 11.4 6.9e-149 496.3 11.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Peptidase_M61 PF05299.12 KKK18832.1 - 0.18 12.2 0.2 0.54 10.7 0.0 1.8 2 0 0 2 2 2 0 M61 glycyl aminopeptidase AMP-binding PF00501.28 KKK18833.1 - 2.3e-58 197.8 0.0 3e-58 197.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KKK18833.1 - 2.7e-12 47.5 0.0 5.3e-12 46.5 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Adenylsucc_synt PF00709.21 KKK18833.1 - 0.16 10.8 0.0 0.36 9.7 0.0 1.5 1 0 0 1 1 1 0 Adenylosuccinate synthetase Topoisom_bac PF01131.20 KKK18835.1 - 9.2e-100 334.5 0.0 1.7e-99 333.7 0.0 1.4 2 0 0 2 2 2 1 DNA topoisomerase Toprim PF01751.22 KKK18835.1 - 2.4e-19 69.5 0.0 9.4e-19 67.5 0.0 2.0 2 0 0 2 2 2 1 Toprim domain DUF4149 PF13664.6 KKK18836.1 - 9.1e-28 96.6 4.8 2.7e-27 95.1 2.4 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) Rab15_effector PF15208.6 KKK18836.1 - 0.16 11.2 0.0 0.22 10.8 0.0 1.1 1 0 0 1 1 1 0 Rab15 effector Peptidase_M41 PF01434.18 KKK18837.1 - 3.5e-65 219.4 0.0 4.2e-65 219.2 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M41 DUF1295 PF06966.12 KKK18838.1 - 3.8e-42 144.4 6.2 4.8e-42 144.1 6.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Lactamase_B PF00753.27 KKK18839.1 - 0.025 14.6 0.0 0.05 13.6 0.0 1.4 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily Pkinase PF00069.25 KKK18841.1 - 4e-13 49.3 0.0 6.9e-13 48.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KKK18841.1 - 0.0039 17.2 0.0 0.0058 16.6 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KKK18841.1 - 0.0045 16.3 0.0 0.0072 15.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KKK18841.1 - 0.011 15.1 0.0 0.016 14.6 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 KKK18841.1 - 0.011 15.0 0.1 0.027 13.8 0.1 1.7 1 1 0 1 1 1 0 Protein tyrosine kinase RIO1 PF01163.22 KKK18841.1 - 0.11 12.1 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Ku_PK_bind PF08785.11 KKK18842.1 - 9.1e-36 122.6 0.1 2.1e-35 121.5 0.1 1.7 1 0 0 1 1 1 1 Ku C terminal domain like Ku PF02735.16 KKK18842.1 - 1.9e-32 112.6 0.0 3e-32 112.0 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 KKK18842.1 - 1.7e-09 37.7 0.0 4.1e-09 36.5 0.0 1.7 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain VWA PF00092.28 KKK18842.1 - 0.0052 17.1 0.0 0.014 15.6 0.0 1.7 1 1 0 1 1 1 1 von Willebrand factor type A domain MFS_1 PF07690.16 KKK18844.1 - 1.1e-22 80.5 48.8 1.1e-22 80.5 47.8 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 KKK18844.1 - 0.94 8.3 26.6 0.054 12.3 0.8 2.9 2 1 1 3 3 3 0 MFS_1 like family LIM PF00412.22 KKK18845.1 - 1.6e-13 50.6 15.0 1.1e-07 31.9 4.2 2.8 2 1 0 2 2 2 2 LIM domain DUF2321 PF10083.9 KKK18845.1 - 0.0047 16.6 5.6 0.028 14.0 0.2 2.2 2 0 0 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2321) Zn_ribbon_17 PF17120.5 KKK18845.1 - 2.8 7.6 13.5 0.21 11.3 2.3 2.8 2 1 0 2 2 2 0 Zinc-ribbon, C4HC2 type SNN_linker PF09050.10 KKK18846.1 - 1.8 8.4 10.7 4.4 7.2 0.3 3.6 3 0 0 3 3 3 0 Stannin unstructured linker Ceramidase PF05875.12 KKK18847.1 - 1.5e-90 303.2 8.9 1.8e-89 299.7 8.9 1.9 1 1 0 1 1 1 1 Ceramidase Peptidase_U4 PF03419.13 KKK18847.1 - 0.038 13.3 8.5 0.57 9.4 8.5 2.1 1 1 0 1 1 1 0 Sporulation factor SpoIIGA DUF4131 PF13567.6 KKK18847.1 - 3.2 7.4 5.8 2.5 7.8 0.1 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) DUF202 PF02656.15 KKK18847.1 - 8.4 6.9 9.6 5.4 7.5 0.3 2.8 3 1 0 3 3 3 0 Domain of unknown function (DUF202) Mito_carr PF00153.27 KKK18848.1 - 9.4e-52 172.9 3.7 3e-18 65.5 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein RTT107_BRCT_5 PF16770.5 KKK18849.1 - 2.6e-34 117.1 0.0 1.7e-30 104.9 0.0 4.2 4 0 0 4 4 4 1 Regulator of Ty1 transposition protein 107 BRCT domain PTCB-BRCT PF12738.7 KKK18849.1 - 3.2e-30 103.9 0.4 1.2e-19 70.0 0.2 5.2 4 1 0 4 4 4 4 twin BRCT domain BRCT PF00533.26 KKK18849.1 - 7.9e-25 87.1 0.0 2.3e-06 27.9 0.0 6.4 6 1 0 6 6 6 4 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 KKK18849.1 - 3.3e-24 85.1 0.0 7.3e-05 23.1 0.0 6.7 7 0 0 7 7 7 5 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 KKK18849.1 - 2.6e-08 34.0 0.0 0.046 14.0 0.0 3.8 3 0 0 3 3 3 3 DNA ligase 3 BRCT domain PRCC PF10253.9 KKK18849.1 - 0.15 12.8 6.6 0.39 11.5 6.6 1.6 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting Abhydrolase_6 PF12697.7 KKK18850.1 - 4.2e-13 50.4 2.7 6.9e-13 49.7 2.6 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KKK18850.1 - 7.5e-08 31.9 0.0 1.3e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KKK18850.1 - 3.4e-05 23.6 0.0 4.8e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Chlorophyllase2 PF12740.7 KKK18850.1 - 0.032 13.1 0.0 0.049 12.5 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme PGAP1 PF07819.13 KKK18850.1 - 0.1 12.3 0.1 0.17 11.6 0.1 1.3 1 0 0 1 1 1 0 PGAP1-like protein Methyltransf_4 PF02390.17 KKK18851.1 - 5.8e-46 156.1 0.0 2.1e-29 102.2 0.0 3.1 3 0 0 3 3 3 3 Putative methyltransferase Methyltransf_25 PF13649.6 KKK18851.1 - 0.0027 18.3 0.0 0.013 16.1 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_32 PF13679.6 KKK18851.1 - 0.005 16.8 0.0 0.0079 16.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KKK18851.1 - 0.0083 15.7 0.0 0.087 12.4 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_31 PF13847.6 KKK18851.1 - 0.021 14.6 0.0 0.035 13.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 KKK18851.1 - 0.027 15.2 0.0 0.078 13.7 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain FmrO PF07091.11 KKK18851.1 - 0.15 11.6 0.0 0.24 10.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) ESCRT-II PF05871.12 KKK18852.1 - 1.6e-49 167.7 0.9 2.3e-49 167.2 0.9 1.2 1 0 0 1 1 1 1 ESCRT-II complex subunit GTP_EFTU PF00009.27 KKK18875.1 - 1.2e-41 142.4 0.0 2.1e-41 141.6 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 KKK18875.1 - 9e-27 93.6 0.7 1.6e-26 92.8 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 KKK18875.1 - 2.3e-07 31.1 0.5 5.9e-07 29.8 0.5 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KKK18875.1 - 0.021 14.9 0.0 0.093 12.8 0.0 2.1 1 1 0 1 1 1 0 50S ribosome-binding GTPase Hamartin PF04388.12 KKK18875.1 - 0.3 9.7 7.2 0.42 9.2 7.2 1.1 1 0 0 1 1 1 0 Hamartin protein CytochromB561_N PF09786.9 KKK18875.1 - 0.52 9.3 6.8 0.77 8.7 6.8 1.2 1 0 0 1 1 1 0 Cytochrome B561, N terminal TFIIA PF03153.13 KKK18875.1 - 0.52 10.3 23.8 0.88 9.5 23.8 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Mitofilin PF09731.9 KKK18875.1 - 0.55 9.0 13.4 0.78 8.5 13.4 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein WGG PF10273.9 KKK18876.1 - 6e-29 100.5 0.3 9.6e-29 99.9 0.3 1.3 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 RRP7 PF12923.7 KKK18876.1 - 0.21 11.7 0.0 0.21 11.7 0.0 2.1 2 0 0 2 2 2 0 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain NOA36 PF06524.12 KKK18876.1 - 0.27 10.5 5.2 0.38 10.0 5.2 1.2 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 KKK18876.1 - 1.6 6.7 8.8 2.3 6.2 8.8 1.2 1 0 0 1 1 1 0 DNA polymerase phi BSD PF03909.17 KKK18877.1 - 1.1e-19 70.2 1.2 2.1e-19 69.3 1.2 1.5 1 0 0 1 1 1 1 BSD domain Suf PF05843.14 KKK18877.1 - 0.094 12.7 3.0 0.19 11.7 3.0 1.5 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Ran-binding PF05508.11 KKK18878.1 - 3.9e-124 413.7 0.9 5.1e-124 413.3 0.9 1.1 1 0 0 1 1 1 1 RanGTP-binding protein Pkinase PF00069.25 KKK18879.1 - 0.06 12.7 0.0 0.079 12.3 0.0 1.1 1 0 0 1 1 1 0 Protein kinase domain WaaY PF06176.11 KKK18879.1 - 0.09 12.4 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Destabilase PF05497.12 KKK18880.1 - 0.1 12.9 0.0 0.18 12.1 0.0 1.3 1 0 0 1 1 1 0 Destabilase Ras PF00071.22 KKK18882.1 - 6.6e-49 165.6 1.4 4.4e-47 159.7 0.5 2.0 2 0 0 2 2 2 2 Ras family Roc PF08477.13 KKK18882.1 - 4.6e-27 94.6 1.1 7.2e-25 87.5 0.3 2.5 3 0 0 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKK18882.1 - 2e-10 40.4 0.1 2.7e-10 40.0 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KKK18882.1 - 8.3e-07 28.7 0.0 1.1e-06 28.3 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KKK18882.1 - 0.00016 21.1 0.0 0.00027 20.4 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 KKK18882.1 - 0.013 15.4 0.2 0.1 12.5 0.1 2.2 2 1 0 2 2 2 0 RsgA GTPase Mitofilin PF09731.9 KKK18883.1 - 6.6e-158 527.4 28.3 1.3e-130 437.2 28.0 2.6 2 1 1 3 3 3 2 Mitochondrial inner membrane protein Glyco_hydro_3_C PF01915.22 KKK18884.1 - 1e-44 152.9 0.0 1.8e-44 152.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KKK18884.1 - 4.5e-35 121.6 0.0 6.9e-35 120.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain zf-RING_2 PF13639.6 KKK18885.1 - 1.2e-06 28.8 3.7 0.00014 22.1 1.3 2.5 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 KKK18885.1 - 2e-06 28.0 1.5 9.5e-06 25.8 0.4 2.3 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KKK18885.1 - 4.8e-05 23.3 1.9 0.00021 21.3 0.6 2.2 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger DNA_pol_phi PF04931.13 KKK18885.1 - 0.0033 15.6 16.2 0.0044 15.2 16.2 1.1 1 0 0 1 1 1 1 DNA polymerase phi PHD PF00628.29 KKK18885.1 - 0.012 15.5 1.1 0.029 14.3 1.1 1.7 1 0 0 1 1 1 0 PHD-finger FANCL_C PF11793.8 KKK18885.1 - 0.048 13.8 4.7 0.3 11.3 2.1 2.5 2 1 0 2 2 2 0 FANCL C-terminal domain PHD_2 PF13831.6 KKK18885.1 - 0.11 12.1 2.1 0.23 11.1 2.1 1.6 1 0 0 1 1 1 0 PHD-finger Cwf_Cwc_15 PF04889.12 KKK18885.1 - 0.15 11.8 18.8 0.042 13.6 15.9 1.5 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein zf-C3HC4_4 PF15227.6 KKK18885.1 - 0.22 11.7 8.2 0.091 12.9 2.4 2.3 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING RINGv PF12906.7 KKK18885.1 - 0.24 11.6 5.8 0.085 13.0 2.8 1.8 2 0 0 2 2 1 0 RING-variant domain CNDH2_C PF16858.5 KKK18885.1 - 0.28 11.0 4.3 0.13 12.2 1.5 1.7 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Nucleo_P87 PF07267.11 KKK18885.1 - 0.44 9.4 7.0 0.64 8.8 7.0 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 zf-C3HC4 PF00097.25 KKK18885.1 - 0.63 10.0 9.7 0.13 12.2 1.5 2.5 3 0 0 3 3 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 KKK18885.1 - 0.93 9.3 6.1 0.41 10.5 1.7 2.5 3 0 0 3 3 2 0 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.6 KKK18885.1 - 0.97 9.5 4.7 9.6 6.3 0.3 2.7 2 0 0 2 2 2 0 RING-type zinc-finger zf-RING-like PF08746.11 KKK18885.1 - 1.3 9.4 5.2 0.24 11.7 1.4 1.8 2 0 0 2 2 1 0 RING-like domain NOA36 PF06524.12 KKK18885.1 - 1.4 8.2 23.2 0.16 11.2 19.2 1.4 2 0 0 2 2 2 0 NOA36 protein FYDLN_acid PF09538.10 KKK18885.1 - 1.7 9.4 20.2 0.23 12.2 13.5 2.7 3 0 0 3 3 2 0 Protein of unknown function (FYDLN_acid) zf-C3HC4_2 PF13923.6 KKK18885.1 - 2.7 7.9 8.5 1.4 8.8 1.5 2.7 3 0 0 3 3 2 0 Zinc finger, C3HC4 type (RING finger) TRAP_alpha PF03896.16 KKK18885.1 - 3.2 6.9 5.8 4.6 6.4 5.8 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit BUD22 PF09073.10 KKK18885.1 - 4.3 6.6 10.6 8.1 5.7 10.6 1.4 1 0 0 1 1 1 0 BUD22 Prok-RING_4 PF14447.6 KKK18885.1 - 5.8 6.9 7.5 2.9 7.8 1.2 2.7 3 0 0 3 3 3 0 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KKK18885.1 - 8.5 6.4 8.5 0.41 10.6 0.5 2.4 3 0 0 3 3 2 0 zinc-RING finger domain TFB6 PF17110.5 KKK18885.1 - 9.1 6.0 7.6 16 5.2 7.6 1.4 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Citrate_synt PF00285.21 KKK18886.1 - 4.8e-95 318.7 0.0 5.8e-95 318.4 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain ABC_tran PF00005.27 KKK18887.1 - 5.6e-47 159.7 0.0 1.6e-25 90.2 0.0 3.8 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KKK18887.1 - 5.5e-14 52.7 2.2 6.7e-05 22.8 0.0 4.3 3 1 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KKK18887.1 - 5.2e-11 42.4 0.3 0.0069 15.9 0.0 4.3 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain Chromo PF00385.24 KKK18887.1 - 1.6e-07 31.1 0.0 3.1e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain MMR_HSR1 PF01926.23 KKK18887.1 - 8.5e-07 29.1 0.0 0.019 15.0 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_23 PF13476.6 KKK18887.1 - 1e-06 29.4 0.0 0.054 14.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 KKK18887.1 - 4.9e-06 26.5 0.0 0.047 13.6 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 KKK18887.1 - 2.8e-05 23.7 3.4 0.11 12.3 0.5 2.9 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_15 PF13175.6 KKK18887.1 - 0.00033 20.5 0.3 0.53 9.9 0.3 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA_13 PF13166.6 KKK18887.1 - 0.00038 19.3 0.0 0.013 14.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 KKK18887.1 - 0.00042 20.6 0.0 0.15 12.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KKK18887.1 - 0.00053 20.3 0.0 0.38 11.0 0.0 3.0 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.17 KKK18887.1 - 0.00073 19.7 2.9 0.27 11.3 0.1 3.9 5 1 0 5 5 3 1 Helicase HerA, central domain SbcCD_C PF13558.6 KKK18887.1 - 0.0014 18.8 0.0 2.5 8.4 0.0 3.3 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit RNA_helicase PF00910.22 KKK18887.1 - 0.0022 18.4 0.0 1.3 9.5 0.0 2.7 2 0 0 2 2 2 1 RNA helicase Dynamin_N PF00350.23 KKK18887.1 - 0.0027 17.8 0.2 0.21 11.6 0.0 3.0 2 1 0 2 2 2 1 Dynamin family AAA_24 PF13479.6 KKK18887.1 - 0.0039 16.9 0.2 0.45 10.2 0.2 2.5 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KKK18887.1 - 0.0073 16.5 0.1 3 8.0 0.0 3.1 3 0 0 3 3 2 1 AAA domain NACHT PF05729.12 KKK18887.1 - 0.0097 15.8 2.9 0.47 10.4 0.0 2.9 3 0 0 3 3 2 1 NACHT domain MeaB PF03308.16 KKK18887.1 - 0.016 14.2 0.1 4.7 6.1 0.1 2.4 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 KKK18887.1 - 0.04 13.6 0.3 11 5.7 0.1 2.7 2 0 0 2 2 2 0 AAA domain MukB PF04310.12 KKK18887.1 - 0.062 13.1 0.0 9.5 6.0 0.0 2.4 2 0 0 2 2 2 0 MukB N-terminal PduV-EutP PF10662.9 KKK18887.1 - 0.069 12.9 0.1 4.6 7.0 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Roc PF08477.13 KKK18887.1 - 0.079 13.2 0.0 23 5.2 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase NB-ARC PF00931.22 KKK18887.1 - 0.094 11.9 1.0 0.68 9.1 0.0 2.7 3 0 0 3 3 3 0 NB-ARC domain Septin PF00735.18 KKK18887.1 - 0.094 12.0 0.0 14 4.9 0.0 2.3 2 0 0 2 2 2 0 Septin DUF815 PF05673.13 KKK18887.1 - 0.1 11.7 0.1 7.7 5.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA PF00004.29 KKK18887.1 - 0.11 12.9 0.0 5.3 7.5 0.0 3.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 KKK18887.1 - 0.13 12.3 0.6 22 5.0 0.0 2.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ALF PF03752.13 KKK18887.1 - 0.14 12.1 2.7 1.4 9.0 0.6 3.0 2 0 0 2 2 2 0 Short repeats of unknown function AAA_18 PF13238.6 KKK18887.1 - 0.14 12.7 0.0 25 5.4 0.0 2.9 3 0 0 3 3 2 0 AAA domain AAA_27 PF13514.6 KKK18887.1 - 0.17 11.4 1.6 9.9 5.7 0.0 2.7 3 0 0 3 3 2 0 AAA domain HEAT PF02985.22 KKK18887.1 - 0.2 12.0 1.9 52 4.5 0.0 4.5 4 0 0 4 4 4 0 HEAT repeat Asp PF00026.23 KKK18888.1 - 1.7e-50 172.2 0.0 2.4e-50 171.7 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KKK18888.1 - 1.9e-07 31.5 0.3 8.8e-06 26.1 0.3 2.3 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KKK18888.1 - 0.0023 18.5 0.1 0.085 13.5 0.0 2.9 2 1 0 2 2 2 1 Aspartyl protease DUF3900 PF13039.6 KKK18888.1 - 0.28 11.1 0.0 0.41 10.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3900) DUF1365 PF07103.11 KKK18889.1 - 7.1e-24 84.8 0.0 1e-23 84.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1365) MARVEL PF01284.23 KKK18891.1 - 2.9e-12 46.8 21.3 4.3e-12 46.3 21.3 1.2 1 0 0 1 1 1 1 Membrane-associating domain PRCC PF10253.9 KKK18891.1 - 0.12 13.2 3.0 0.14 12.9 3.0 1.1 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting 7TMR-DISM_7TM PF07695.11 KKK18891.1 - 0.19 11.6 20.1 1 9.2 5.9 2.0 1 1 1 2 2 2 0 7TM diverse intracellular signalling Abhydrolase_3 PF07859.13 KKK18892.1 - 2.6e-53 181.0 0.2 3.3e-53 180.7 0.2 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KKK18892.1 - 6.1e-14 51.7 0.0 8.3e-14 51.2 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Abhydrolase_2 PF02230.16 KKK18892.1 - 0.0014 18.5 0.0 0.0022 17.8 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 KKK18892.1 - 0.0026 17.3 0.0 0.0097 15.4 0.0 1.9 1 1 0 1 1 1 1 Prolyl oligopeptidase family Thioesterase PF00975.20 KKK18892.1 - 0.098 12.8 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Esterase PF00756.20 KKK18892.1 - 0.11 12.2 0.0 0.18 11.4 0.0 1.4 1 1 0 1 1 1 0 Putative esterase BAAT_C PF08840.11 KKK18892.1 - 0.13 12.1 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Pyr_redox_3 PF13738.6 KKK18893.1 - 2.7e-06 26.9 0.2 0.0092 15.3 0.0 2.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KKK18893.1 - 0.00022 20.6 0.0 0.0047 16.2 0.0 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KKK18893.1 - 0.00031 19.3 0.8 0.0037 15.7 0.0 2.6 2 1 1 3 3 3 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 KKK18893.1 - 0.0029 16.8 0.2 0.094 11.8 0.1 2.5 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Trehalose_PPase PF02358.16 KKK18893.1 - 0.096 11.8 0.0 0.58 9.2 0.0 2.0 2 0 0 2 2 2 0 Trehalose-phosphatase DAO PF01266.24 KKK18893.1 - 0.59 9.6 3.3 2.3 7.7 2.5 2.3 2 1 1 3 3 3 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KKK18894.1 - 7e-17 61.6 0.0 6.8e-15 55.1 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KKK18894.1 - 1.6e-14 53.9 0.0 7.3e-14 51.7 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KKK18894.1 - 1.3e-13 50.2 0.0 4.6e-13 48.4 0.0 1.8 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 KKK18894.1 - 2.6e-13 50.0 0.0 5.4e-09 36.2 0.0 2.9 2 1 0 2 2 2 2 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 KKK18894.1 - 7.3e-10 38.5 0.4 6.7e-08 32.0 0.0 2.6 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 KKK18894.1 - 7.5e-08 32.5 2.2 0.0047 16.9 0.1 4.3 3 1 0 3 3 3 2 FAD-NAD(P)-binding Pyr_redox PF00070.27 KKK18894.1 - 4.4e-07 30.4 0.1 0.012 16.2 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KKK18894.1 - 2.9e-06 27.1 0.0 0.00014 21.6 0.0 3.1 4 0 0 4 4 4 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KKK18894.1 - 8.2e-06 24.8 0.2 0.061 12.0 0.0 3.0 4 0 0 4 4 4 2 HI0933-like protein Thi4 PF01946.17 KKK18894.1 - 4.4e-05 22.8 0.0 0.019 14.2 0.0 2.9 3 0 0 3 3 3 1 Thi4 family Lycopene_cycl PF05834.12 KKK18894.1 - 0.00014 21.1 0.0 0.016 14.3 0.0 2.9 2 1 0 2 2 2 1 Lycopene cyclase protein FAD_binding_3 PF01494.19 KKK18894.1 - 0.00033 20.0 0.1 0.014 14.6 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain FAD_binding_2 PF00890.24 KKK18894.1 - 0.00062 19.0 0.0 0.0088 15.2 0.0 2.4 3 0 0 3 3 3 1 FAD binding domain 2-Hacid_dh_C PF02826.19 KKK18894.1 - 0.014 14.8 0.0 0.029 13.7 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 KKK18894.1 - 0.053 13.6 0.0 4.3 7.4 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase FAD_oxidored PF12831.7 KKK18894.1 - 0.094 12.0 0.0 7.1 5.8 0.0 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 KKK18894.1 - 0.13 12.7 0.0 24 5.4 0.0 2.5 2 0 0 2 2 2 0 Putative NAD(P)-binding HK PF02110.15 KKK18894.1 - 0.17 11.3 0.1 0.27 10.6 0.1 1.2 1 0 0 1 1 1 0 Hydroxyethylthiazole kinase family adh_short PF00106.25 KKK18895.1 - 4.1e-41 140.6 0.0 5.3e-41 140.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KKK18895.1 - 1.9e-27 96.3 0.0 2.4e-27 96.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 KKK18895.1 - 0.0074 15.7 0.0 0.079 12.3 0.0 2.0 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) PAE PF03283.13 KKK18895.1 - 0.058 12.5 0.0 0.077 12.1 0.0 1.1 1 0 0 1 1 1 0 Pectinacetylesterase NmrA PF05368.13 KKK18895.1 - 0.15 11.5 0.0 0.24 10.9 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family ketoacyl-synt PF00109.26 KKK18896.1 - 4.3e-68 229.6 0.1 4.3e-68 229.6 0.1 2.6 3 0 0 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 KKK18896.1 - 1.6e-55 188.8 0.1 4e-55 187.6 0.0 1.7 2 0 0 2 2 2 1 Acyl transferase domain PS-DH PF14765.6 KKK18896.1 - 2.3e-41 142.0 0.3 4.4e-41 141.1 0.3 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 KKK18896.1 - 6.2e-34 116.5 0.1 2.2e-33 114.7 0.0 2.1 2 0 0 2 2 1 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.10 KKK18896.1 - 8.9e-29 100.7 0.0 2.1e-28 99.5 0.0 1.7 1 0 0 1 1 1 1 KR domain Methyltransf_12 PF08242.12 KKK18896.1 - 1.3e-18 67.6 0.0 3e-18 66.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 KKK18896.1 - 3.1e-18 66.2 0.0 7.6e-18 65.0 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_23 PF13489.6 KKK18896.1 - 4.4e-11 42.9 0.0 1.1e-10 41.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKK18896.1 - 7.3e-10 39.4 0.0 2.7e-09 37.6 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.25 KKK18896.1 - 7.9e-07 29.3 0.3 2.1e-06 28.0 0.3 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_31 PF13847.6 KKK18896.1 - 1.1e-06 28.6 0.0 2.1e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KKK18896.1 - 1.2e-06 29.0 0.0 4.4e-06 27.2 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.23 KKK18896.1 - 0.00063 19.2 0.1 0.0016 17.8 0.1 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain Ubie_methyltran PF01209.18 KKK18896.1 - 0.012 15.0 0.0 0.021 14.2 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family adh_short PF00106.25 KKK18896.1 - 0.019 14.4 0.0 0.076 12.5 0.0 2.0 1 0 0 1 1 1 0 short chain dehydrogenase ACP_syn_III PF08545.10 KKK18896.1 - 0.059 13.2 1.8 0.13 12.1 0.5 2.3 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III FAD_binding_3 PF01494.19 KKK18897.1 - 8.6e-26 91.0 5.2 2.8e-24 86.0 5.2 2.7 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KKK18897.1 - 6.5e-05 22.7 0.3 0.0038 16.9 0.1 2.5 3 0 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KKK18897.1 - 0.0007 19.8 0.3 0.0035 17.5 0.2 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KKK18897.1 - 0.00078 18.6 1.4 0.00086 18.5 0.2 1.8 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.6 KKK18897.1 - 0.0035 16.6 0.3 0.022 14.0 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KKK18897.1 - 0.033 13.4 0.1 0.071 12.3 0.1 1.5 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.12 KKK18897.1 - 0.33 10.0 5.7 0.13 11.3 1.3 2.3 2 1 0 2 2 2 0 Lycopene cyclase protein Sugar_tr PF00083.24 KKK18898.1 - 5.7e-80 269.4 21.9 6.3e-80 269.2 21.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKK18898.1 - 9.9e-38 130.0 50.0 5.5e-35 120.9 27.7 1.5 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KKK18898.1 - 3.1e-06 26.0 6.2 3.1e-06 26.0 6.2 2.3 2 0 0 2 2 2 1 MFS/sugar transport protein TRI12 PF06609.13 KKK18898.1 - 7.5e-06 24.6 7.4 2.2e-05 23.1 4.1 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.7 KKK18898.1 - 9.9e-05 21.4 0.3 0.0008 18.4 0.3 2.4 1 1 0 1 1 1 1 MFS_1 like family MFS_3 PF05977.13 KKK18898.1 - 0.79 8.0 12.9 0.04 12.3 2.2 2.8 3 1 1 4 4 4 0 Transmembrane secretion effector Fungal_trans PF04082.18 KKK18900.1 - 6.9e-14 51.5 0.0 4.1e-13 49.0 0.0 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain Aldo_ket_red PF00248.21 KKK18901.1 - 1.1e-53 182.4 0.0 1.4e-53 182.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family p450 PF00067.22 KKK18903.1 - 4.6e-57 193.8 0.0 6.8e-57 193.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 MMR_HSR1 PF01926.23 KKK18904.1 - 1.7e-06 28.1 0.1 2.3e-05 24.4 0.1 2.9 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KKK18904.1 - 5.3e-05 23.7 0.1 0.0016 18.9 0.0 3.1 3 0 0 3 3 3 1 AAA ATPase domain AIG1 PF04548.16 KKK18904.1 - 0.00041 19.7 0.0 0.65 9.3 0.0 2.7 2 0 0 2 2 2 2 AIG1 family RsgA_GTPase PF03193.16 KKK18904.1 - 0.00097 19.1 0.1 0.0055 16.6 0.0 2.3 2 1 0 2 2 1 1 RsgA GTPase AAA_29 PF13555.6 KKK18904.1 - 0.0026 17.4 0.0 0.0063 16.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_24 PF13479.6 KKK18904.1 - 0.004 16.9 0.1 0.041 13.6 0.0 2.7 3 0 0 3 3 3 1 AAA domain TniB PF05621.11 KKK18904.1 - 0.0046 16.4 0.0 0.017 14.5 0.0 1.9 1 0 0 1 1 1 1 Bacterial TniB protein FtsK_SpoIIIE PF01580.18 KKK18904.1 - 0.012 15.0 0.0 0.029 13.7 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family T2SSE PF00437.20 KKK18904.1 - 0.016 14.3 0.0 0.034 13.2 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein Septin PF00735.18 KKK18904.1 - 0.02 14.2 0.2 0.082 12.2 0.2 2.1 1 1 0 1 1 1 0 Septin GTP_EFTU PF00009.27 KKK18904.1 - 0.02 14.4 0.0 0.061 12.9 0.0 1.8 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 KKK18904.1 - 0.02 14.9 4.5 2.7 8.0 0.0 3.6 3 0 0 3 3 3 0 Dynamin family AAA_23 PF13476.6 KKK18904.1 - 0.048 14.2 0.0 0.048 14.2 0.0 3.0 2 1 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KKK18904.1 - 0.055 14.0 2.6 0.47 11.0 0.0 3.1 3 0 0 3 3 3 0 ABC transporter UPF0231 PF06062.11 KKK18904.1 - 0.062 13.6 4.9 0.18 12.1 1.1 2.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0231) YfbU PF03887.14 KKK18904.1 - 0.065 13.2 0.8 0.19 11.8 0.8 1.7 1 0 0 1 1 1 0 YfbU domain Sigma54_activat PF00158.26 KKK18904.1 - 0.068 12.9 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Ca_bind_SSO6904 PF18249.1 KKK18904.1 - 0.091 13.1 0.5 0.31 11.4 0.0 2.1 2 0 0 2 2 1 0 Calcium binding protein SSO6904 AAA_22 PF13401.6 KKK18904.1 - 0.12 12.6 0.0 1.2 9.4 0.0 2.8 3 0 0 3 3 1 0 AAA domain RNA_helicase PF00910.22 KKK18904.1 - 0.13 12.7 0.1 0.87 10.0 0.0 2.5 2 0 0 2 2 2 0 RNA helicase NACHT PF05729.12 KKK18904.1 - 0.14 12.1 0.1 1.4 8.8 0.0 2.7 3 0 0 3 3 3 0 NACHT domain G-alpha PF00503.20 KKK18904.1 - 0.17 11.0 3.3 0.23 10.6 0.0 2.6 3 1 0 3 3 3 0 G-protein alpha subunit DUF87 PF01935.17 KKK18904.1 - 0.18 11.9 0.0 0.18 11.9 0.0 3.7 3 1 0 3 3 3 0 Helicase HerA, central domain Snf7 PF03357.21 KKK18904.1 - 0.19 11.3 8.6 0.017 14.7 3.3 2.0 2 0 0 2 2 2 0 Snf7 Fic PF02661.18 KKK18906.1 - 0.13 13.1 0.1 0.28 12.1 0.1 1.5 1 0 0 1 1 1 0 Fic/DOC family Methyltransf_25 PF13649.6 KKK18907.1 - 1.8e-19 70.2 0.0 1.4e-18 67.4 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KKK18907.1 - 4e-17 62.7 0.0 1.1e-16 61.3 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KKK18907.1 - 5.3e-12 45.9 0.0 6.8e-12 45.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KKK18907.1 - 6.3e-10 39.1 0.0 1e-09 38.4 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KKK18907.1 - 6.6e-09 36.4 0.0 1.7e-08 35.1 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.20 KKK18907.1 - 4.9e-06 26.0 0.0 6e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.14 KKK18907.1 - 0.0051 16.4 0.0 0.0086 15.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Pox_MCEL PF03291.16 KKK18907.1 - 0.022 13.9 0.0 0.11 11.5 0.0 1.9 1 1 1 2 2 2 0 mRNA capping enzyme MetW PF07021.12 KKK18907.1 - 0.032 13.8 0.0 0.053 13.1 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltr_RsmB-F PF01189.17 KKK18907.1 - 0.05 13.2 0.0 6.1 6.4 0.0 2.1 2 0 0 2 2 2 0 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 KKK18907.1 - 0.073 13.2 0.0 1.1 9.3 0.0 2.1 1 1 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_9 PF08003.11 KKK18907.1 - 0.17 10.8 0.0 0.3 10.0 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1698) Aegerolysin PF06355.13 KKK18908.1 - 1.3e-36 125.6 0.4 1.4e-36 125.4 0.4 1.0 1 0 0 1 1 1 1 Aegerolysin Zn_clus PF00172.18 KKK18909.1 - 0.00032 20.8 5.2 0.00087 19.4 5.2 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldo_ket_red PF00248.21 KKK18911.1 - 1e-42 146.4 0.0 9.8e-41 139.9 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Reoviridae_Vp9 PF08978.10 KKK18911.1 - 0.07 12.3 0.0 0.1 11.8 0.0 1.1 1 0 0 1 1 1 0 Reoviridae VP9 GMC_oxred_C PF05199.13 KKK18912.1 - 3e-10 40.8 0.0 1e-09 39.1 0.0 1.9 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_N PF00732.19 KKK18912.1 - 2.9e-07 30.1 0.0 6.3e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KKK18912.1 - 0.00038 19.6 0.7 0.00061 19.0 0.7 1.3 1 0 0 1 1 1 1 FAD binding domain Abhydrolase_1 PF00561.20 KKK18912.1 - 0.00096 18.9 0.0 0.3 10.7 0.0 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold NAD_binding_8 PF13450.6 KKK18912.1 - 0.0023 18.1 0.5 0.0079 16.4 0.5 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KKK18912.1 - 0.013 14.7 0.0 0.023 13.9 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KKK18912.1 - 0.015 15.9 0.0 0.039 14.5 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Glyco_trans_4_2 PF13477.6 KKK18912.1 - 0.12 12.4 0.0 0.34 10.9 0.0 1.7 1 0 0 1 1 1 0 Glycosyl transferase 4-like FAD_oxidored PF12831.7 KKK18912.1 - 0.15 11.4 3.1 0.24 10.7 3.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Glyco_transf_56 PF07429.11 KKK18912.1 - 0.22 10.6 0.0 0.37 9.9 0.0 1.2 1 0 0 1 1 1 0 4-alpha-L-fucosyltransferase glycosyl transferase group 56 HemolysinCabind PF00353.19 KKK18912.1 - 2.2 8.4 6.1 5.1 7.2 6.1 1.6 1 0 0 1 1 1 0 RTX calcium-binding nonapeptide repeat (4 copies) Fungal_trans PF04082.18 KKK18913.1 - 1.7e-10 40.4 0.0 3.5e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 KKK18913.1 - 1.2e-07 31.7 14.6 0.0014 19.0 5.4 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KKK18913.1 - 1.1e-06 28.7 17.6 6.8e-06 26.3 5.2 3.7 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KKK18913.1 - 0.00046 20.8 17.8 0.028 15.2 1.6 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KKK18913.1 - 0.0026 17.7 13.3 0.16 12.0 1.9 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2HC_2 PF13913.6 KKK18913.1 - 0.008 16.1 1.2 0.008 16.1 1.2 2.1 2 0 0 2 2 2 1 zinc-finger of a C2HC-type zf-C2H2_8 PF15909.5 KKK18913.1 - 0.085 13.2 4.3 0.38 11.1 4.4 2.1 2 0 0 2 2 2 0 C2H2-type zinc ribbon Ysc84 PF04366.12 KKK18914.1 - 5.6e-47 158.7 0.1 8.5e-47 158.1 0.1 1.3 1 0 0 1 1 1 1 Las17-binding protein actin regulator FSA_C PF10479.9 KKK18915.1 - 1.1 7.3 22.6 1.5 6.8 22.6 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Dicty_REP PF05086.12 KKK18915.1 - 2.7 5.9 8.0 3.3 5.6 8.0 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Herpes_capsid PF06112.11 KKK18915.1 - 6.2 6.9 14.6 14 5.7 14.6 1.7 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein DUF2235 PF09994.9 KKK18916.1 - 1.3e-78 264.3 0.0 1.7e-78 263.9 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Peptidase_S10 PF00450.22 KKK18917.1 - 1.3e-102 344.4 7.1 1.6e-102 344.1 7.1 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase PHO4 PF01384.20 KKK18918.1 - 1.4e-115 386.0 11.4 1.8e-115 385.6 11.4 1.2 1 0 0 1 1 1 1 Phosphate transporter family cobW PF02492.19 KKK18918.1 - 4.8e-47 159.8 5.1 3.5e-36 124.4 0.9 2.3 1 1 1 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 KKK18918.1 - 2.7e-20 72.1 0.3 5.4e-16 58.3 0.0 2.7 3 0 0 3 3 3 2 Cobalamin synthesis protein cobW C-terminal domain MobB PF03205.14 KKK18918.1 - 0.0064 16.4 0.1 0.012 15.5 0.1 1.4 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B TsaE PF02367.17 KKK18918.1 - 0.0086 16.1 0.1 0.018 15.0 0.1 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_29 PF13555.6 KKK18918.1 - 0.023 14.4 0.0 0.082 12.7 0.0 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 KKK18918.1 - 0.031 14.7 0.1 0.08 13.3 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 KKK18918.1 - 0.052 13.7 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 KKK18918.1 - 0.06 12.4 0.1 0.12 11.4 0.1 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein MeaB PF03308.16 KKK18918.1 - 0.083 11.9 0.4 1 8.3 0.0 2.4 2 1 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Viral_helicase1 PF01443.18 KKK18918.1 - 0.11 12.2 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase ATPase_2 PF01637.18 KKK18918.1 - 0.13 12.2 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea PTPRCAP PF15713.5 KKK18918.1 - 1.5 9.1 8.5 0.058 13.7 1.1 2.3 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated HHH_5 PF14520.6 KKK18919.1 - 0.0001 22.8 0.0 0.25 12.0 0.0 2.3 2 0 0 2 2 2 2 Helix-hairpin-helix domain UPF0181 PF03701.14 KKK18919.1 - 0.17 11.6 0.1 0.29 10.8 0.1 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0181) FAD_binding_3 PF01494.19 KKK18920.1 - 2.3e-72 244.2 0.0 3.3e-72 243.6 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KKK18920.1 - 0.0004 19.7 0.0 0.0029 16.9 0.0 2.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KKK18920.1 - 0.0015 18.7 0.1 0.004 17.4 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KKK18920.1 - 0.0025 17.1 0.0 0.0053 16.0 0.0 1.5 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 KKK18920.1 - 0.014 14.2 0.0 0.023 13.4 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.6 KKK18920.1 - 0.014 14.6 0.0 0.024 13.9 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KKK18920.1 - 0.035 13.2 0.0 0.46 9.5 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain Pyr_redox PF00070.27 KKK18920.1 - 0.058 13.9 0.0 0.18 12.4 0.0 1.9 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KKK18920.1 - 0.059 12.9 0.0 0.28 10.7 0.0 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_oxidored PF12831.7 KKK18920.1 - 0.11 11.8 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase IF-2B PF01008.17 KKK18921.1 - 1.1e-61 208.5 0.3 1.4e-59 201.6 0.3 2.3 1 1 0 1 1 1 1 Initiation factor 2 subunit family NIF PF03031.18 KKK18922.1 - 1e-59 200.8 0.0 1.5e-59 200.2 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Ndc1_Nup PF09531.10 KKK18922.1 - 0.33 9.6 2.9 0.39 9.3 2.9 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup AIM5 PF17050.5 KKK18923.1 - 1.2e-14 54.9 1.9 1.6e-14 54.5 1.9 1.2 1 0 0 1 1 1 1 Altered inheritance of mitochondria 5 Rpn9_C PF18261.1 KKK18923.1 - 0.0076 15.8 0.4 0.018 14.6 0.4 1.6 1 0 0 1 1 1 1 Rpn9 C-terminal helix DUF5315 PF17242.2 KKK18924.1 - 1.1e-25 89.2 1.6 1.1e-25 89.2 1.6 1.7 2 0 0 2 2 2 1 Disordered region of unknown function (DUF5315) Ribosom_S12_S23 PF00164.25 KKK18925.1 - 3.5e-51 171.6 0.6 4.6e-51 171.2 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Methyltransf_15 PF09445.10 KKK18925.1 - 0.01 15.4 0.0 0.011 15.3 0.0 1.1 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Mononeg_mRNAcap PF14318.6 KKK18925.1 - 0.19 10.9 0.0 0.23 10.7 0.0 1.1 1 0 0 1 1 1 0 Mononegavirales mRNA-capping region V zf-AN1 PF01428.16 KKK18938.1 - 7.4e-13 48.4 5.9 7.4e-13 48.4 5.9 1.6 1 1 0 1 1 1 1 AN1-like Zinc finger Transp_Tc5_C PF04236.15 KKK18938.1 - 0.18 12.2 6.5 0.096 13.1 4.6 1.5 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain Pkinase PF00069.25 KKK18939.1 - 2.4e-21 76.3 0.0 1.2e-20 74.0 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK18939.1 - 0.00036 19.9 0.0 0.00092 18.6 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase DUF1754 PF08555.10 KKK18940.1 - 2.6e-17 63.4 7.4 2.6e-17 63.4 7.4 1.5 2 0 0 2 2 2 1 Eukaryotic family of unknown function (DUF1754) Aldo_ket_red PF00248.21 KKK18941.1 - 7e-54 183.0 0.0 8e-54 182.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family EamA PF00892.20 KKK18942.1 - 4.1e-12 46.4 28.5 4.4e-06 26.9 20.8 2.4 2 0 0 2 2 2 2 EamA-like transporter family Metallophos PF00149.28 KKK18942.1 - 5.3e-10 40.1 0.2 1.4e-09 38.8 0.2 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KKK18942.1 - 2.6e-06 27.7 0.2 0.00011 22.4 0.2 2.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain CSG2 PF16965.5 KKK18942.1 - 2.2e-05 23.6 10.7 9.2e-05 21.6 10.7 2.0 1 1 0 1 1 1 1 Ceramide synthase regulator DUF202 PF02656.15 KKK18942.1 - 0.011 16.2 2.9 0.011 16.2 2.9 4.6 3 2 1 4 4 4 0 Domain of unknown function (DUF202) Nuc_sug_transp PF04142.15 KKK18942.1 - 0.43 9.7 7.9 1.8 7.6 5.5 2.6 2 1 0 2 2 2 0 Nucleotide-sugar transporter MASE3 PF17159.4 KKK18942.1 - 0.58 9.8 10.8 0.016 14.9 3.4 2.1 2 0 0 2 2 2 0 Membrane-associated sensor domain Actin PF00022.19 KKK18943.1 - 9.5e-112 373.6 0.0 6.6e-111 370.8 0.0 1.8 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 KKK18943.1 - 0.021 13.6 0.0 0.095 11.5 0.0 2.0 1 1 0 1 1 1 0 MreB/Mbl protein Actin_micro PF17003.5 KKK18943.1 - 0.22 10.7 0.4 0.99 8.5 0.1 1.9 2 0 0 2 2 2 0 Putative actin-like family DUF1325 PF07039.11 KKK18944.1 - 8.7e-34 116.4 0.0 1.5e-33 115.7 0.0 1.4 1 0 0 1 1 1 1 SGF29 tudor-like domain LBR_tudor PF09465.10 KKK18944.1 - 0.013 15.2 0.0 0.024 14.4 0.0 1.4 1 0 0 1 1 1 0 Lamin-B receptor of TUDOR domain PMI_typeI PF01238.21 KKK18945.1 - 8.5e-149 495.8 0.0 9.9e-149 495.6 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I Cupin_2 PF07883.11 KKK18945.1 - 0.025 14.3 0.1 0.47 10.2 0.0 2.2 2 0 0 2 2 2 0 Cupin domain AraC_binding PF02311.19 KKK18945.1 - 0.07 13.0 0.0 18 5.2 0.0 2.9 3 0 0 3 3 3 0 AraC-like ligand binding domain IRK_C PF17655.1 KKK18945.1 - 0.21 11.2 0.0 0.34 10.5 0.0 1.3 1 0 0 1 1 1 0 Inward rectifier potassium channel C-terminal domain Coatomer_E PF04733.14 KKK18946.1 - 2.8e-38 132.0 0.5 3.2e-38 131.8 0.5 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_19 PF14559.6 KKK18946.1 - 3.1e-06 27.6 4.8 0.0003 21.2 0.6 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 KKK18946.1 - 0.00085 19.9 5.0 0.01 16.6 0.3 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 KKK18946.1 - 0.0012 18.8 2.5 0.025 14.7 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 KKK18946.1 - 0.0019 18.8 8.1 0.0057 17.3 1.5 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 KKK18946.1 - 0.019 15.1 2.2 1.5 9.0 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 KKK18946.1 - 0.025 14.4 0.1 0.18 11.7 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 KKK18946.1 - 0.079 13.3 3.4 0.3 11.4 0.2 2.6 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_4 PF07721.14 KKK18946.1 - 1.5 9.6 5.7 1 10.2 0.6 3.1 3 1 1 4 4 4 0 Tetratricopeptide repeat Reprolysin_4 PF13583.6 KKK18947.1 - 1e-35 123.2 0.4 1e-35 123.2 0.4 1.5 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 KKK18947.1 - 1.4e-30 107.0 1.4 1.4e-30 107.0 1.4 1.6 2 0 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.6 KKK18947.1 - 5.5e-16 59.0 0.1 5.5e-16 59.0 0.1 1.7 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Pep_M12B_propep PF01562.19 KKK18947.1 - 0.00064 20.0 0.0 0.0022 18.2 0.0 1.9 1 1 0 1 1 1 1 Reprolysin family propeptide Reprolysin PF01421.19 KKK18947.1 - 0.0018 18.2 0.1 0.0088 16.0 0.1 2.0 1 1 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease NAD_binding_2 PF03446.15 KKK18948.1 - 2e-28 99.6 0.1 2.9e-28 99.0 0.1 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 KKK18948.1 - 3.5e-11 43.4 0.0 6.7e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 KKK18948.1 - 0.0025 18.4 0.0 0.0082 16.7 0.0 1.9 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent RuvC_1 PF18516.1 KKK18948.1 - 0.026 13.7 0.0 0.034 13.3 0.0 1.1 1 0 0 1 1 1 0 RuvC nuclease domain Shikimate_DH PF01488.20 KKK18948.1 - 0.059 13.4 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF3425 PF11905.8 KKK18949.1 - 8e-23 80.8 1.2 1.3e-22 80.1 1.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 KKK18949.1 - 0.0028 17.7 8.5 0.024 14.7 6.1 2.4 1 1 1 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 KKK18949.1 - 0.34 11.0 11.6 2.3 8.4 11.6 2.2 1 1 0 1 1 1 0 Basic region leucine zipper MCPVI PF02993.14 KKK18949.1 - 0.77 9.6 6.1 0.88 9.4 4.5 1.8 1 1 1 2 2 2 0 Minor capsid protein VI GTP_cyclohydro2 PF00925.20 KKK18950.1 - 3e-57 192.8 0.0 4.3e-57 192.3 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase II Tubulin PF00091.25 KKK18951.1 - 6.3e-62 209.3 0.0 9.8e-62 208.7 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KKK18951.1 - 2.8e-44 150.3 1.0 3.7e-44 149.9 0.2 1.6 2 0 0 2 2 2 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 KKK18951.1 - 1.7e-05 25.1 0.0 4.7e-05 23.7 0.0 1.8 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Hrs_helical PF12210.8 KKK18951.1 - 0.19 12.3 0.1 0.49 11.0 0.1 1.6 1 0 0 1 1 1 0 Hepatocyte growth factor-regulated tyrosine kinase substrate ERGIC_N PF13850.6 KKK18953.1 - 1.7e-23 82.8 0.0 2.4e-23 82.3 0.0 1.2 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) COPIIcoated_ERV PF07970.12 KKK18953.1 - 0.0013 18.6 0.0 0.0029 17.5 0.0 1.5 1 1 0 1 1 1 1 Endoplasmic reticulum vesicle transporter Pex24p PF06398.11 KKK18954.1 - 1.3e-54 185.6 0.0 1.5e-54 185.4 0.0 1.0 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Pkinase PF00069.25 KKK18955.1 - 6.3e-54 183.1 0.0 9.8e-54 182.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK18955.1 - 1.2e-19 70.7 0.0 1.9e-19 69.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KKK18955.1 - 0.11 12.5 0.0 0.5 10.2 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 KKK18955.1 - 0.11 11.8 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ABC_tran PF00005.27 KKK18956.1 - 4.2e-42 143.9 0.0 8e-24 84.7 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KKK18956.1 - 7e-35 121.0 22.4 1.4e-22 80.7 10.7 3.5 3 0 0 3 3 3 3 ABC transporter transmembrane region SMC_N PF02463.19 KKK18956.1 - 1.8e-11 43.9 4.3 0.00019 21.0 0.1 4.2 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KKK18956.1 - 5.1e-06 26.5 6.6 0.016 15.1 0.1 4.3 2 2 1 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KKK18956.1 - 1.6e-05 25.5 3.4 0.00044 20.8 0.3 2.5 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KKK18956.1 - 6.2e-05 23.3 2.0 0.045 14.0 0.0 3.4 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KKK18956.1 - 0.0002 21.0 2.4 0.11 12.2 0.1 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 KKK18956.1 - 0.00027 21.0 0.0 0.4 10.8 0.0 2.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KKK18956.1 - 0.00059 20.3 1.1 0.33 11.3 0.0 3.4 2 1 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 KKK18956.1 - 0.0013 19.2 0.0 1.2 9.6 0.0 3.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 KKK18956.1 - 0.0016 17.6 0.3 0.66 9.0 0.0 2.5 2 0 0 2 2 2 2 Type II/IV secretion system protein RsgA_GTPase PF03193.16 KKK18956.1 - 0.002 18.0 0.3 0.51 10.2 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_25 PF13481.6 KKK18956.1 - 0.0029 17.2 0.5 3.5 7.1 0.0 3.5 3 1 0 3 3 3 1 AAA domain NACHT PF05729.12 KKK18956.1 - 0.0034 17.3 0.0 1.4 8.9 0.0 2.9 2 0 0 2 2 2 1 NACHT domain AAA_30 PF13604.6 KKK18956.1 - 0.0049 16.6 0.1 4.2 7.1 0.0 3.0 2 1 0 2 2 2 1 AAA domain cobW PF02492.19 KKK18956.1 - 0.007 16.0 0.9 0.87 9.1 0.2 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_15 PF13175.6 KKK18956.1 - 0.011 15.5 0.0 1.5 8.5 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain AAA_7 PF12775.7 KKK18956.1 - 0.037 13.6 0.2 2.2 7.8 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region SbcCD_C PF13558.6 KKK18956.1 - 0.042 14.1 0.1 14 6.0 0.0 2.9 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_13 PF13166.6 KKK18956.1 - 0.051 12.2 1.2 6.8 5.2 0.0 3.3 4 0 0 4 4 4 0 AAA domain TrwB_AAD_bind PF10412.9 KKK18956.1 - 0.08 11.8 0.9 8.8 5.1 0.3 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain RNA_helicase PF00910.22 KKK18956.1 - 0.081 13.3 0.0 18 5.8 0.0 2.6 2 0 0 2 2 2 0 RNA helicase NB-ARC PF00931.22 KKK18956.1 - 0.17 11.0 0.5 11 5.1 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain DUF2075 PF09848.9 KKK18956.1 - 0.21 10.8 1.1 2.8 7.1 0.0 2.5 3 0 0 3 3 2 0 Uncharacterized conserved protein (DUF2075) AAA_33 PF13671.6 KKK18956.1 - 0.23 11.6 0.8 5.7 7.1 0.0 2.7 2 1 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 KKK18956.1 - 0.49 10.1 1.3 8.7 6.1 0.2 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF87 PF01935.17 KKK18956.1 - 0.59 10.2 3.7 0.21 11.6 0.4 1.9 2 0 0 2 2 2 0 Helicase HerA, central domain FeoB_C PF07664.12 KKK18956.1 - 0.64 9.8 4.1 0.33 10.7 0.2 2.8 2 0 0 2 2 1 0 Ferrous iron transport protein B C terminus Pkinase PF00069.25 KKK18958.1 - 2.9e-14 53.1 0.0 1.3e-13 50.9 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK18958.1 - 0.0014 18.0 0.0 0.0025 17.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase AsmA_1 PF13109.6 KKK18958.1 - 0.013 15.0 0.0 0.018 14.5 0.0 1.1 1 0 0 1 1 1 0 AsmA-like C-terminal region AAT PF03417.16 KKK18961.1 - 1.1e-24 87.5 0.0 1.4e-24 87.1 0.0 1.1 1 0 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase Pkinase PF00069.25 KKK18962.1 - 9.6e-20 71.0 0.0 1.6e-19 70.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK18962.1 - 7.4e-14 51.6 0.0 4.1e-13 49.2 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase CorA PF01544.18 KKK18963.1 - 0.0012 18.3 4.5 0.0023 17.3 4.5 1.6 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Hemerythrin PF01814.23 KKK18964.1 - 3.1e-08 34.3 0.8 5.8e-08 33.4 0.8 1.3 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain PS-DH PF14765.6 KKK18965.1 - 2.9e-62 210.6 0.0 9.2e-62 209.0 0.0 1.8 2 0 0 2 2 2 1 Polyketide synthase dehydratase KR PF08659.10 KKK18965.1 - 2.4e-56 190.5 0.8 2.4e-55 187.2 0.2 2.5 2 0 0 2 2 2 1 KR domain Acyl_transf_1 PF00698.21 KKK18965.1 - 5.7e-52 177.2 0.3 9.3e-52 176.5 0.3 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KKK18965.1 - 3.3e-31 107.7 0.1 9.1e-31 106.3 0.1 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.12 KKK18965.1 - 2.6e-19 69.8 0.0 1.2e-18 67.7 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.6 KKK18965.1 - 1.5e-16 61.7 0.1 5.6e-15 56.6 0.0 3.5 3 0 0 3 3 3 1 Zinc-binding dehydrogenase KAsynt_C_assoc PF16197.5 KKK18965.1 - 3.7e-16 59.6 0.0 9.1e-16 58.3 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension ADH_zinc_N PF00107.26 KKK18965.1 - 4.8e-16 58.9 0.2 5.8e-15 55.4 0.0 3.0 3 0 0 3 3 3 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.6 KKK18965.1 - 1e-14 54.7 0.0 2.2e-14 53.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKK18965.1 - 7e-12 45.9 0.0 4.9e-11 43.2 0.0 2.7 3 0 0 3 3 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KKK18965.1 - 3.9e-10 40.2 0.0 1.6e-09 38.3 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KKK18965.1 - 2.5e-08 33.8 0.0 1.2e-07 31.6 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain adh_short PF00106.25 KKK18965.1 - 2.6e-08 33.5 0.2 7.1e-06 25.6 0.0 2.8 2 0 0 2 2 2 1 short chain dehydrogenase ketoacyl-synt PF00109.26 KKK18965.1 - 4.5e-08 33.0 0.0 1.1e-07 31.7 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain PP-binding PF00550.25 KKK18965.1 - 7.7e-08 32.6 0.1 2.1e-07 31.2 0.1 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site ADH_N PF08240.12 KKK18965.1 - 5.6e-06 26.2 0.0 5.1e-05 23.1 0.0 2.4 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Ubie_methyltran PF01209.18 KKK18965.1 - 2.3e-05 23.8 0.0 5.3e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.9 KKK18965.1 - 0.0012 18.6 0.0 0.012 15.4 0.0 2.5 3 0 0 3 3 3 1 Lysine methyltransferase adh_short_C2 PF13561.6 KKK18965.1 - 0.005 16.4 0.0 0.018 14.6 0.0 1.9 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase NodS PF05401.11 KKK18965.1 - 0.0077 15.9 0.0 0.02 14.5 0.0 1.6 1 0 0 1 1 1 1 Nodulation protein S (NodS) SAT PF16073.5 KKK18965.1 - 0.067 12.9 2.2 9.1 5.9 0.0 2.8 3 0 0 3 3 3 0 Starter unit:ACP transacylase in aflatoxin biosynthesis Rad51 PF08423.11 KKK18967.1 - 1.4e-06 27.7 0.0 0.00049 19.5 0.0 2.2 2 0 0 2 2 2 2 Rad51 PSY3 PF16836.5 KKK18967.1 - 0.084 12.4 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 Shu complex component Psy3, DNA-binding description PALP PF00291.25 KKK18968.1 - 1.2e-44 152.9 1.0 1.4e-44 152.7 1.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme TAF8_C PF10406.9 KKK18969.1 - 1.7e-22 79.7 1.0 4.1e-22 78.5 1.0 1.7 1 0 0 1 1 1 1 Transcription factor TFIID complex subunit 8 C-term Bromo_TP PF07524.13 KKK18969.1 - 3.1e-09 36.7 0.0 1.5e-08 34.5 0.0 2.0 2 0 0 2 2 2 1 Bromodomain associated Mitochondr_Som1 PF11093.8 KKK18970.1 - 3.8e-24 84.5 0.0 4.9e-24 84.1 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial export protein Som1 DUF2040 PF09745.9 KKK18971.1 - 1.1e-35 122.3 10.5 1.1e-35 122.3 10.5 3.0 2 1 0 2 2 2 1 Coiled-coil domain-containing protein 55 (DUF2040) Isochorismatase PF00857.20 KKK18972.1 - 2.8e-39 135.1 0.0 6.4e-39 133.9 0.0 1.6 2 0 0 2 2 2 1 Isochorismatase family FAR1 PF03101.15 KKK18972.1 - 4.3e-05 24.1 0.0 7.5e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 FAR1 DNA-binding domain AFT PF08731.11 KKK18972.1 - 0.065 13.6 0.0 0.11 12.9 0.0 1.3 1 0 0 1 1 1 0 Transcription factor AFT Sedlin_N PF04628.13 KKK18973.1 - 1.3e-31 109.5 0.0 1.5e-30 106.0 0.0 1.9 1 1 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 KKK18973.1 - 0.0024 17.8 0.0 0.0039 17.1 0.0 1.3 1 0 0 1 1 1 1 Sybindin-like family K_channel_TID PF07941.11 KKK18973.1 - 2 8.9 9.5 2 8.9 8.2 1.7 1 1 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain Response_reg PF00072.24 KKK18974.1 - 1e-19 70.7 0.0 3.8e-13 49.6 0.0 2.3 2 0 0 2 2 2 2 Response regulator receiver domain PQ-loop PF04193.14 KKK18975.1 - 4e-17 61.7 1.0 4e-17 61.7 1.0 3.1 3 1 0 3 3 3 1 PQ loop repeat Vpu PF00558.19 KKK18975.1 - 0.094 12.5 3.4 0.22 11.3 0.3 2.4 2 0 0 2 2 2 0 Vpu protein Syndecan PF01034.20 KKK18975.1 - 0.29 11.1 1.4 6.6 6.7 0.0 3.1 3 0 0 3 3 3 0 Syndecan domain SH3_1 PF00018.28 KKK18976.1 - 4.5e-10 39.0 0.1 8.9e-10 38.0 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KKK18976.1 - 3.6e-06 26.6 0.0 7.4e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 KKK18976.1 - 1.7e-05 24.5 0.0 3.2e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Herpes_LMP1 PF05297.11 KKK18976.1 - 0.00027 20.3 2.7 0.00059 19.1 0.1 2.0 2 0 0 2 2 2 1 Herpesvirus latent membrane protein 1 (LMP1) SH3_10 PF17902.1 KKK18976.1 - 0.14 12.3 0.0 0.24 11.5 0.0 1.4 1 0 0 1 1 1 0 SH3 domain DUF2069 PF09842.9 KKK18976.1 - 0.24 11.6 6.0 0.68 10.2 3.8 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2069) TMEM220 PF15071.6 KKK18976.1 - 5.1 7.9 6.6 6.2 7.6 5.4 1.8 1 1 0 1 1 1 0 Transmembrane family 220, helix Bot1p PF12298.8 KKK18977.1 - 5.3e-58 196.0 3.4 5.3e-58 196.0 3.4 2.0 2 0 0 2 2 2 1 Eukaryotic mitochondrial regulator protein R3H PF01424.22 KKK19014.1 - 9e-11 41.6 0.0 1.7e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 R3H domain SUZ-C PF12901.7 KKK19014.1 - 9.8e-07 28.7 4.0 2.5e-06 27.4 4.0 1.7 1 0 0 1 1 1 1 SUZ-C motif RRM_1 PF00076.22 KKK19014.1 - 3.9e-06 26.6 0.1 7.2e-06 25.7 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pkinase PF00069.25 KKK19016.1 - 1.3e-06 28.0 0.0 1.6e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KKK19016.1 - 0.00039 19.8 0.2 0.00061 19.2 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KKK19016.1 - 0.035 14.0 0.8 0.32 10.9 0.3 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KKK19016.1 - 0.058 12.2 0.0 0.083 11.7 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase EcKinase PF02958.20 KKK19016.1 - 0.083 12.2 0.2 1.3 8.2 0.1 2.0 1 1 0 2 2 2 0 Ecdysteroid kinase DAO PF01266.24 KKK19017.1 - 6.3e-35 121.4 0.1 9.2e-35 120.9 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KKK19017.1 - 0.0065 15.8 0.0 0.1 11.8 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KKK19017.1 - 0.027 13.7 0.0 0.051 12.8 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Antimicrobial12 PF08107.11 KKK19017.1 - 0.047 13.5 0.5 0.14 12.0 0.5 1.8 1 0 0 1 1 1 0 Pleurocidin family Pkinase PF00069.25 KKK19018.1 - 7.1e-19 68.2 0.0 1.1e-14 54.5 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KKK19018.1 - 0.00024 20.5 0.0 0.00075 18.9 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Glyco_hydro_28 PF00295.17 KKK19019.1 - 7.2e-121 403.2 20.1 8.2e-121 403.0 20.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 DUF2993 PF11209.8 KKK19019.1 - 0.038 14.2 1.1 0.15 12.3 0.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2993) dCMP_cyt_deam_1 PF00383.23 KKK19020.1 - 3.6e-10 39.6 0.0 5.9e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KKK19020.1 - 5.6e-07 29.4 0.1 8.8e-06 25.5 0.1 2.2 1 1 0 1 1 1 1 MafB19-like deaminase Bd3614-deam PF14439.6 KKK19020.1 - 0.35 10.9 0.9 0.86 9.7 0.9 1.6 1 1 0 1 1 1 0 Bd3614-like deaminase Glyco_transf_22 PF03901.17 KKK19021.1 - 1.6e-79 268.1 15.5 1.9e-79 267.9 15.5 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Aminotran_3 PF00202.21 KKK19022.1 - 3.6e-120 401.3 0.0 4.2e-120 401.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 KKK19022.1 - 0.0022 17.2 0.0 0.0041 16.3 0.0 1.4 2 0 0 2 2 2 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 KKK19022.1 - 0.011 15.0 0.0 0.02 14.2 0.0 1.4 1 0 0 1 1 1 0 Beta-eliminating lyase CBM_14 PF01607.24 KKK19023.1 - 1.9e-09 37.5 5.7 3.3e-09 36.8 5.6 1.4 1 1 0 1 1 1 1 Chitin binding Peritrophin-A domain Lustrin_cystein PF14625.6 KKK19023.1 - 0.65 10.4 6.6 0.45 10.9 0.8 2.1 1 1 1 2 2 2 0 Lustrin, cysteine-rich repeated domain FAA_hydrolase PF01557.18 KKK19024.1 - 3e-51 174.2 0.0 4e-51 173.8 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.11 KKK19024.1 - 1.5e-21 76.6 0.0 8.6e-21 74.1 0.0 2.3 3 0 0 3 3 3 1 Fumarylacetoacetase N-terminal MFS_1 PF07690.16 KKK19025.1 - 4.8e-37 127.7 50.1 7.2e-37 127.1 41.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KKK19025.1 - 5.9e-11 41.9 14.3 5.9e-11 41.9 14.3 3.2 3 0 0 3 3 3 2 Sugar (and other) transporter SUR7 PF06687.12 KKK19026.1 - 9.3e-18 64.6 3.6 1.1e-17 64.4 3.6 1.0 1 0 0 1 1 1 1 SUR7/PalI family Fig1 PF12351.8 KKK19026.1 - 0.0013 18.7 3.8 0.0013 18.7 3.8 1.5 2 0 0 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 DUF4282 PF14110.6 KKK19026.1 - 0.036 14.8 0.4 0.036 14.8 0.4 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4282) Glyco_hydro_127 PF07944.12 KKK19027.1 - 7.9e-24 84.0 0.1 2.3e-20 72.6 0.0 2.1 2 0 0 2 2 2 2 Beta-L-arabinofuranosidase, GH127 2OG-FeII_Oxy_2 PF13532.6 KKK19027.1 - 1.3e-15 58.1 0.0 2.6e-15 57.1 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Glyoxalase PF00903.25 KKK19028.1 - 0.052 13.8 0.0 0.1 12.8 0.0 1.5 1 1 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily TFIID-31kDa PF02291.15 KKK19042.1 - 2.7e-19 69.5 0.0 1.2e-18 67.3 0.0 1.9 1 1 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit FAM176 PF14851.6 KKK19042.1 - 0.018 14.7 1.5 0.018 14.7 1.5 3.3 3 1 0 3 3 3 0 FAM176 family MDM10 PF12519.8 KKK19042.1 - 0.063 12.1 0.0 0.063 12.1 0.0 1.8 2 0 0 2 2 2 0 Mitochondrial distribution and morphology protein 10 Spt20 PF12090.8 KKK19042.1 - 0.16 11.5 12.2 0.11 12.1 1.6 2.1 2 0 0 2 2 2 0 Spt20 family Pex14_N PF04695.13 KKK19042.1 - 2 9.1 9.2 4.8 7.8 1.8 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4171 PF13775.6 KKK19042.1 - 4.2 7.8 11.3 4.3 7.8 9.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4171) SP_C-Propep PF08999.10 KKK19043.1 - 0.0019 18.0 4.2 0.0022 17.7 4.2 1.2 1 0 0 1 1 1 1 Surfactant protein C, N terminal propeptide Photo_RC PF00124.19 KKK19043.1 - 0.021 14.1 0.0 0.024 13.9 0.0 1.1 1 0 0 1 1 1 0 Photosynthetic reaction centre protein DUF4658 PF15555.6 KKK19043.1 - 0.57 10.3 4.3 0.68 10.1 4.3 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4658) DUF677 PF05055.12 KKK19043.1 - 2.9 6.7 8.2 3.1 6.6 8.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF677) Shisa PF13908.6 KKK19043.1 - 7.7 6.7 5.9 9.2 6.5 5.9 1.3 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator Glyco_transf_90 PF05686.12 KKK19044.1 - 2.8e-18 66.0 2.0 1.9e-14 53.4 1.5 2.8 2 1 0 2 2 2 2 Glycosyl transferase family 90 Ferric_reduct PF01794.19 KKK19044.1 - 1.2e-10 41.5 0.8 1.2e-10 41.5 0.8 2.2 2 0 0 2 2 2 1 Ferric reductase like transmembrane component tRNA_synthFbeta PF17759.1 KKK19045.1 - 8.8e-50 169.1 0.0 1.2e-49 168.6 0.0 1.2 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain PhetRS_B1 PF18262.1 KKK19045.1 - 2.5e-34 117.3 0.2 7.1e-33 112.7 0.1 2.4 2 0 0 2 2 2 1 Phe-tRNA synthetase beta subunit B1 domain B3_4 PF03483.17 KKK19045.1 - 1.4e-24 86.8 0.1 2.8e-24 85.7 0.1 1.6 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.15 KKK19045.1 - 1.4e-17 63.8 0.0 4.2e-15 55.8 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetase B5 domain HEAT PF02985.22 KKK19046.1 - 7.4e-39 128.4 10.8 0.015 15.5 0.1 13.0 13 0 0 13 13 13 10 HEAT repeat HEAT_2 PF13646.6 KKK19046.1 - 6.3e-37 125.8 0.9 9.9e-11 41.9 0.0 8.2 2 2 6 8 8 8 8 HEAT repeats HEAT_EZ PF13513.6 KKK19046.1 - 6e-14 52.2 6.3 0.015 15.8 0.0 9.4 7 3 4 11 11 11 3 HEAT-like repeat Vac14_Fab1_bd PF12755.7 KKK19046.1 - 6.9e-12 45.8 1.1 0.0033 18.0 0.0 7.3 5 2 1 8 8 8 1 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 KKK19046.1 - 5.9e-09 36.2 8.6 0.019 15.0 0.2 5.6 4 1 0 6 6 6 2 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 KKK19046.1 - 6.2e-07 28.3 3.8 1.8e-05 23.5 0.6 3.5 2 1 1 3 3 3 2 Adaptin N terminal region RTP1_C1 PF10363.9 KKK19046.1 - 0.00015 21.9 5.2 0.64 10.2 0.1 4.7 4 1 1 5 5 5 1 Required for nuclear transport of RNA pol II C-terminus 1 CLASP_N PF12348.8 KKK19046.1 - 0.0018 17.9 0.7 0.14 11.7 0.1 3.6 3 2 1 4 4 4 1 CLASP N terminal TetR_C_16 PF17920.1 KKK19046.1 - 0.0089 16.2 0.9 14 6.0 0.0 4.0 3 1 1 4 4 4 1 Tetracyclin repressor-like, C-terminal domain Proteasom_PSMB PF10508.9 KKK19046.1 - 0.31 9.5 2.7 6.2 5.2 0.4 2.3 2 1 0 2 2 2 0 Proteasome non-ATPase 26S subunit Arm PF00514.23 KKK19046.1 - 2.4 8.3 4.8 35 4.6 0.0 4.4 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat Myotub-related PF06602.14 KKK19047.1 - 3.7e-151 503.0 0.0 6.2e-151 502.3 0.0 1.3 1 1 0 1 1 1 1 Myotubularin-like phosphatase domain Ribosomal_S3_C PF00189.20 KKK19047.1 - 1.3e-23 83.3 0.1 4.2e-23 81.7 0.2 1.9 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 KKK19047.1 - 4.6e-11 42.4 0.1 9e-11 41.4 0.1 1.5 1 0 0 1 1 1 1 KH domain HECT PF00632.25 KKK19049.1 - 1.3e-78 264.6 0.0 1.9e-78 264.0 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) HEAT PF02985.22 KKK19049.1 - 0.0032 17.6 3.9 0.21 11.9 0.0 4.4 5 0 0 5 5 5 1 HEAT repeat HEAT_EZ PF13513.6 KKK19049.1 - 0.026 15.1 0.2 0.35 11.4 0.0 3.0 3 0 0 3 3 3 0 HEAT-like repeat Arm PF00514.23 KKK19049.1 - 0.03 14.4 6.9 18 5.6 0.1 5.8 5 1 1 6 6 6 0 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.20 KKK19049.1 - 0.49 8.9 4.3 0.24 9.9 0.2 2.4 3 0 0 3 3 3 0 Adaptin N terminal region SIS PF01380.22 KKK19050.1 - 3.1e-13 49.7 0.0 1.2e-12 47.8 0.0 2.0 1 1 0 1 1 1 1 SIS domain SIS_2 PF13580.6 KKK19050.1 - 2.8e-08 33.9 0.1 1.4e-05 25.1 0.1 2.4 1 1 1 2 2 2 2 SIS domain CTP_transf_like PF01467.26 KKK19051.1 - 4.2e-27 95.1 0.0 6e-27 94.6 0.0 1.2 1 0 0 1 1 1 1 Cytidylyltransferase-like Peptidase_C13 PF01650.18 KKK19051.1 - 0.17 11.4 0.0 0.27 10.7 0.0 1.2 1 0 0 1 1 1 0 Peptidase C13 family VIT1 PF01988.19 KKK19054.1 - 2.8e-60 203.9 4.8 3.4e-60 203.6 4.8 1.1 1 0 0 1 1 1 1 VIT family APH PF01636.23 KKK19056.1 - 0.0015 18.5 0.2 0.0019 18.2 0.2 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family VPS9 PF02204.18 KKK19057.1 - 1e-29 102.8 0.0 1.7e-29 102.1 0.0 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF5601 PF18151.1 KKK19057.1 - 1.2e-15 57.5 0.2 3.4e-15 56.1 0.2 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF5601) CUE PF02845.16 KKK19057.1 - 1.8e-09 37.1 0.2 2.3e-08 33.6 0.0 2.3 2 0 0 2 2 2 1 CUE domain Asn_synthase PF00733.21 KKK19058.1 - 5.1e-16 59.3 0.3 8.6e-06 25.6 0.0 3.1 2 1 1 3 3 3 3 Asparagine synthase GATase_7 PF13537.6 KKK19058.1 - 1.2e-06 28.4 0.0 1e-05 25.4 0.0 2.4 2 0 0 2 2 2 1 Glutamine amidotransferase domain DUF3700 PF12481.8 KKK19058.1 - 3.6e-06 26.6 0.0 6.9e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Aluminium induced protein GATase_6 PF13522.6 KKK19058.1 - 2.8e-05 24.3 0.0 0.00067 19.9 0.0 2.7 2 0 0 2 2 2 1 Glutamine amidotransferase domain bZIP_2 PF07716.15 KKK19059.1 - 1.1e-05 25.4 9.8 1.1e-05 25.4 9.8 2.1 3 0 0 3 3 3 1 Basic region leucine zipper bZIP_1 PF00170.21 KKK19059.1 - 0.00034 20.6 10.2 0.00071 19.6 10.2 1.5 1 0 0 1 1 1 1 bZIP transcription factor LPD23 PF18838.1 KKK19059.1 - 0.13 12.0 0.8 0.35 10.7 0.8 1.7 1 0 0 1 1 1 0 Large polyvalent protein associated domain 23 TPR_14 PF13428.6 KKK19059.1 - 0.22 12.4 1.7 0.49 11.3 1.7 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF4964 PF16334.5 KKK19059.1 - 0.37 10.4 2.0 2.8 7.6 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4964) KilA-N PF04383.13 KKK19060.1 - 0.00017 21.4 0.0 0.0044 16.8 0.0 2.2 1 1 0 1 1 1 1 KilA-N domain PPP5 PF08321.12 KKK19069.1 - 9e-34 115.7 0.2 2.1e-33 114.4 0.2 1.7 1 0 0 1 1 1 1 PPP5 TPR repeat region Metallophos PF00149.28 KKK19069.1 - 8.2e-31 108.1 0.0 1.2e-30 107.6 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase TPR_1 PF00515.28 KKK19069.1 - 1.2e-10 40.7 4.6 0.00023 20.9 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 KKK19069.1 - 5.6e-09 35.4 6.6 0.0062 16.6 0.1 3.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 KKK19069.1 - 1.5e-05 24.6 1.7 0.46 10.2 0.0 3.5 2 1 0 3 3 3 2 TPR repeat TPR_19 PF14559.6 KKK19069.1 - 0.00016 22.1 0.4 0.23 12.0 0.0 3.0 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 KKK19069.1 - 0.00029 21.4 6.6 0.012 16.3 0.1 3.2 2 1 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 KKK19069.1 - 0.0023 18.1 0.2 0.0063 16.6 0.2 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.6 KKK19069.1 - 0.0045 17.1 3.2 2.1 8.8 0.0 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 KKK19069.1 - 0.0081 16.7 1.1 1.9 9.3 0.1 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat MIT PF04212.18 KKK19069.1 - 0.034 14.2 2.6 1.3 9.2 0.4 2.5 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_14 PF13428.6 KKK19069.1 - 0.11 13.4 1.5 2.1 9.4 0.4 3.1 1 1 2 3 3 3 0 Tetratricopeptide repeat Aminotran_3 PF00202.21 KKK19070.1 - 6.8e-119 397.1 0.0 8e-119 396.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Spt4 PF06093.13 KKK19071.1 - 2.8e-32 110.6 0.1 3.4e-32 110.4 0.1 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger DUF2293 PF10056.9 KKK19072.1 - 7.4e-29 99.8 1.1 3.2e-28 97.8 0.0 2.5 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2293) Adap_comp_sub PF00928.21 KKK19075.1 - 1e-91 307.0 0.0 1.4e-91 306.6 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KKK19075.1 - 6.9e-06 26.1 2.8 1.1e-05 25.4 2.8 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.9 KKK19075.1 - 0.12 11.8 0.0 0.51 9.7 0.0 1.9 2 0 0 2 2 2 0 Muniscin C-terminal mu homology domain NAD_binding_5 PF07994.12 KKK19082.1 - 2.1e-144 480.8 0.1 2.5e-144 480.6 0.1 1.1 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.17 KKK19082.1 - 6.5e-46 155.1 0.4 1.2e-45 154.2 0.4 1.5 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase LIM PF00412.22 KKK19083.1 - 1.4e-18 66.8 15.8 1.9e-11 44.0 2.2 2.8 3 1 0 3 3 3 2 LIM domain Cytochrom_c3_2 PF14537.6 KKK19083.1 - 1 9.8 5.0 3.4 8.2 5.0 2.0 1 0 0 1 1 1 0 Cytochrome c3 Cytochrome_C7 PF14522.6 KKK19083.1 - 2.3 8.3 8.3 0.24 11.4 3.3 1.9 2 0 0 2 2 2 0 Cytochrome c7 and related cytochrome c TspO_MBR PF03073.15 KKK19084.1 - 3.4e-43 146.9 9.9 3.4e-43 146.9 9.9 2.8 3 1 1 4 4 4 1 TspO/MBR family MIP PF00230.20 KKK19084.1 - 1.9e-26 93.2 9.7 3.8e-26 92.2 9.7 1.5 1 0 0 1 1 1 1 Major intrinsic protein PIP5K PF01504.18 KKK19085.1 - 2.6e-100 335.2 0.0 3.4e-100 334.8 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase zf-CCHC_6 PF15288.6 KKK19085.1 - 0.16 11.8 2.6 0.34 10.8 2.6 1.5 1 0 0 1 1 1 0 Zinc knuckle SRA1 PF07304.11 KKK19094.1 - 2.1e-12 47.1 0.0 2.2e-12 47.0 0.0 1.1 1 0 0 1 1 1 1 Steroid receptor RNA activator (SRA1) Prp18 PF02840.15 KKK19094.1 - 0.0012 18.9 0.1 0.0042 17.1 0.1 1.8 1 1 0 1 1 1 1 Prp18 domain DUF313 PF03754.13 KKK19094.1 - 0.082 13.1 0.0 0.1 12.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF313) Fibroin_P25 PF07294.11 KKK19094.1 - 0.095 12.7 0.0 0.36 10.9 0.0 1.7 1 1 1 2 2 2 0 Fibroin P25 DUF5569 PF17729.1 KKK19094.1 - 0.12 12.2 0.0 0.14 12.0 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5569) EutQ PF06249.12 KKK19103.1 - 6.6e-12 45.4 0.0 8.2e-12 45.1 0.0 1.1 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ Cupin_3 PF05899.12 KKK19103.1 - 4.3e-08 32.8 0.0 5.9e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_2 PF07883.11 KKK19103.1 - 1.8e-05 24.4 0.0 2.5e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Cupin domain Pirin PF02678.16 KKK19103.1 - 0.0079 16.2 0.0 0.018 15.0 0.0 1.4 1 1 0 1 1 1 1 Pirin DUF3857 PF12969.7 KKK19103.1 - 0.014 15.4 0.0 0.016 15.3 0.0 1.3 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3857) cNMP_binding PF00027.29 KKK19103.1 - 0.052 13.6 0.0 0.088 12.9 0.0 1.4 1 0 0 1 1 1 0 Cyclic nucleotide-binding domain SH3BGR PF04908.15 KKK19103.1 - 0.071 13.3 0.0 0.15 12.2 0.0 1.6 2 0 0 2 2 2 0 SH3-binding, glutamic acid-rich protein Cupin_6 PF12852.7 KKK19103.1 - 0.16 11.7 0.0 0.18 11.5 0.0 1.1 1 0 0 1 1 1 0 Cupin Fungal_trans_2 PF11951.8 KKK19104.1 - 9.1e-63 212.4 0.8 1.2e-62 212.0 0.8 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain PALB2_WD40 PF16756.5 KKK19104.1 - 0.12 11.3 0.0 0.21 10.5 0.0 1.3 1 0 0 1 1 1 0 Partner and localizer of BRCA2 WD40 domain DUF1687 PF07955.11 KKK19105.1 - 3.6e-16 59.8 0.0 4.7e-16 59.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1687) Pkinase PF00069.25 KKK19106.1 - 6.5e-59 199.5 0.0 5.4e-58 196.4 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK19106.1 - 3.2e-27 95.5 0.4 3.3e-19 69.2 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.24 KKK19106.1 - 1.5e-05 25.6 0.6 4.2e-05 24.2 0.6 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain APH PF01636.23 KKK19106.1 - 0.0012 18.8 0.5 0.16 11.8 0.0 2.8 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kinase-like PF14531.6 KKK19106.1 - 0.0044 16.4 0.1 0.022 14.1 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 KKK19106.1 - 0.013 14.8 0.5 0.091 12.1 0.0 2.4 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KKK19106.1 - 0.017 14.1 0.0 0.046 12.7 0.0 1.8 1 1 0 1 1 1 0 Haspin like kinase domain DUF3237 PF11578.8 KKK19107.1 - 1.8e-19 70.1 0.0 6.7e-19 68.2 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF3237) zf-BED PF02892.15 KKK19107.1 - 0.0003 20.8 4.5 0.19 11.8 0.5 2.7 2 0 0 2 2 2 2 BED zinc finger zf-C2H2_2 PF12756.7 KKK19107.1 - 0.015 15.6 4.6 1.2 9.5 0.2 2.3 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) DUF4699 PF15770.5 KKK19107.1 - 0.14 11.9 2.5 0.21 11.4 2.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4699) DUF866 PF05907.13 KKK19107.1 - 0.59 10.0 3.1 9 6.2 0.1 2.8 3 0 0 3 3 3 0 Eukaryotic protein of unknown function (DUF866) PyrI_C PF02748.15 KKK19107.1 - 0.96 9.4 6.0 7.2 6.6 0.5 2.4 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Zn_Tnp_IS91 PF14319.6 KKK19107.1 - 1.4 9.0 13.5 0.78 9.8 2.2 2.7 3 0 0 3 3 3 0 Transposase zinc-binding domain Asn_synthase PF00733.21 KKK19108.1 - 2e-63 215.2 0.0 2.7e-63 214.8 0.0 1.1 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.6 KKK19108.1 - 1.2e-36 125.3 0.0 2e-36 124.6 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 KKK19108.1 - 2.6e-29 102.1 0.0 4.3e-29 101.4 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 KKK19108.1 - 0.00072 19.1 0.0 0.0014 18.1 0.0 1.4 1 0 0 1 1 1 1 Aluminium induced protein ICL PF00463.21 KKK19109.1 - 8.6e-186 618.5 0.0 1.1e-185 618.2 0.0 1.0 1 0 0 1 1 1 1 Isocitrate lyase family DUF1077 PF06417.12 KKK19111.1 - 3.2e-49 165.8 3.8 4e-49 165.5 3.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) Aminotran_5 PF00266.19 KKK19112.1 - 1.6e-07 30.6 0.0 7.2e-07 28.5 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 KKK19112.1 - 0.012 15.0 0.0 0.018 14.3 0.0 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 KKK19112.1 - 0.035 12.6 0.0 0.13 10.7 0.0 1.7 1 1 1 2 2 2 0 Cys/Met metabolism PLP-dependent enzyme Pox_Ag35 PF03286.14 KKK19112.1 - 0.045 13.5 0.3 0.072 12.9 0.3 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein CWC25 PF12542.8 KKK19113.1 - 1.8e-22 80.1 0.0 1.8e-22 80.1 0.0 3.8 3 1 0 3 3 3 1 Pre-mRNA splicing factor Cir_N PF10197.9 KKK19113.1 - 2.9e-14 52.9 9.8 2.9e-14 52.9 9.8 4.5 3 1 1 4 4 4 2 N-terminal domain of CBF1 interacting co-repressor CIR Adaptin_N PF01602.20 KKK19114.1 - 4.6e-116 388.4 10.4 5.9e-116 388.1 10.4 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KKK19114.1 - 8.6e-58 194.9 9.6 7.2e-57 191.9 0.4 3.5 3 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KKK19114.1 - 3.8e-13 49.6 5.2 0.0002 21.7 0.0 5.4 4 2 0 4 4 4 3 HEAT repeats HEAT PF02985.22 KKK19114.1 - 6.8e-09 35.2 3.5 0.034 14.4 0.0 5.9 7 0 0 7 7 7 3 HEAT repeat Atx10homo_assoc PF09759.9 KKK19114.1 - 0.00022 21.2 0.1 8.7 6.4 0.0 4.0 3 1 0 3 3 3 2 Spinocerebellar ataxia type 10 protein domain Arm PF00514.23 KKK19114.1 - 0.0026 17.7 4.0 0.88 9.7 0.0 4.5 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 KKK19114.1 - 0.0053 17.2 5.9 13 6.4 0.0 6.3 6 1 1 7 7 7 1 HEAT-like repeat TIP120 PF08623.10 KKK19114.1 - 0.022 14.6 1.6 2.6 7.8 0.1 3.0 3 0 0 3 3 3 0 TATA-binding protein interacting (TIP20) CLASP_N PF12348.8 KKK19114.1 - 0.035 13.7 2.5 1 8.9 0.0 3.1 4 0 0 4 4 4 0 CLASP N terminal Paf67 PF10255.9 KKK19115.1 - 2e-159 531.0 0.0 2.3e-159 530.7 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_2 PF07719.17 KKK19115.1 - 0.087 13.0 0.0 0.6 10.4 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Fe-S_biosyn PF01521.20 KKK19116.1 - 3.2e-11 43.4 0.0 8.9e-11 42.0 0.0 1.7 1 1 0 1 1 1 1 Iron-sulphur cluster biosynthesis Ribosomal_S11 PF00411.19 KKK19117.1 - 1.7e-46 157.1 1.1 2.2e-46 156.8 1.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 CBM_25 PF03423.13 KKK19117.1 - 0.1 12.8 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Carbohydrate binding domain (family 25) AAR2 PF05282.11 KKK19118.1 - 4.1e-98 329.1 0.0 5.1e-98 328.7 0.0 1.1 1 0 0 1 1 1 1 AAR2 protein VHP PF02209.19 KKK19118.1 - 0.094 12.8 0.3 6.2 7.0 0.0 2.6 3 0 0 3 3 3 0 Villin headpiece domain Kelch_6 PF13964.6 KKK19118.1 - 0.12 12.7 0.0 0.28 11.5 0.0 1.6 1 0 0 1 1 1 0 Kelch motif Aminotran_4 PF01063.19 KKK19119.1 - 3.8e-28 98.9 0.0 6.8e-28 98.1 0.0 1.4 1 0 0 1 1 1 1 Amino-transferase class IV Fungal_trans PF04082.18 KKK19120.1 - 1.3e-16 60.4 0.3 2.2e-16 59.7 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain PDH PF02153.17 KKK19121.1 - 5.3e-15 55.1 0.0 7.5e-15 54.6 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydrogenase F420_oxidored PF03807.17 KKK19121.1 - 1.5e-06 28.7 0.0 3.1e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 KKK19121.1 - 1e-05 25.8 0.0 1.7e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.19 KKK19121.1 - 0.0026 17.1 0.0 0.0047 16.3 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.16 KKK19121.1 - 0.0044 16.7 0.0 0.009 15.7 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 KKK19121.1 - 0.032 14.1 0.0 0.06 13.2 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.18 KKK19121.1 - 0.035 14.4 0.0 0.14 12.4 0.0 2.0 2 0 0 2 2 2 0 TrkA-N domain DUF2185 PF09951.9 KKK19121.1 - 0.051 13.4 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2185) PocR PF10114.9 KKK19121.1 - 0.11 12.3 0.0 14 5.5 0.0 2.5 3 0 0 3 3 3 0 Sensory domain found in PocR IlvN PF07991.12 KKK19121.1 - 0.16 11.5 0.0 0.27 10.8 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain AMP-binding PF00501.28 KKK19122.1 - 5.4e-83 278.9 0.0 7.5e-83 278.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AA_permease PF00324.21 KKK19123.1 - 2.6e-135 451.7 51.4 3.2e-135 451.4 51.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KKK19123.1 - 2.8e-34 118.7 57.4 3.4e-34 118.4 57.4 1.1 1 0 0 1 1 1 1 Amino acid permease WW PF00397.26 KKK19124.1 - 8.1e-13 48.2 1.2 1.9e-12 47.0 1.2 1.7 1 0 0 1 1 1 1 WW domain DUF2012 PF09430.10 KKK19125.1 - 1.9e-20 73.2 0.0 4.2e-20 72.1 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF2012) Mito_carr PF00153.27 KKK19126.1 - 3.6e-49 164.6 1.3 1.3e-17 63.5 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein AphA_like PF14557.6 KKK19126.1 - 0.021 14.5 0.0 0.049 13.4 0.0 1.6 2 0 0 2 2 2 0 Putative AphA-like transcriptional regulator PrcB_C PF14343.6 KKK19126.1 - 0.048 13.8 0.0 1.7 8.9 0.0 2.5 2 0 0 2 2 2 0 PrcB C-terminal UcrQ PF02939.16 KKK19126.1 - 0.055 13.4 0.1 0.28 11.1 0.1 2.2 2 0 0 2 2 2 0 UcrQ family TadE PF07811.12 KKK19126.1 - 0.14 12.4 0.7 2.1 8.7 0.1 2.5 2 0 0 2 2 2 0 TadE-like protein Ssl1 PF04056.14 KKK19127.1 - 4.5e-77 258.2 0.0 6.6e-77 257.7 0.0 1.2 1 0 0 1 1 1 1 Ssl1-like C1_4 PF07975.12 KKK19127.1 - 3.2e-19 68.9 9.1 3.2e-19 68.9 9.1 2.5 2 1 0 2 2 2 1 TFIIH C1-like domain VWA_2 PF13519.6 KKK19127.1 - 3e-16 60.0 0.0 6e-16 59.0 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 KKK19127.1 - 5.9e-07 29.9 0.0 8.6e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain PsiE PF06146.12 KKK19127.1 - 0.017 15.5 0.0 0.035 14.5 0.0 1.5 1 0 0 1 1 1 0 Phosphate-starvation-inducible E Ras PF00071.22 KKK19128.1 - 3.1e-23 82.1 0.3 3.7e-23 81.9 0.3 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KKK19128.1 - 0.0023 18.1 0.2 0.0061 16.8 0.1 1.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Peptidase_M1 PF01433.20 KKK19129.1 - 7.1e-85 284.0 5.7 1.2e-84 283.3 4.4 1.9 2 0 0 2 2 2 1 Peptidase family M1 domain ERAP1_C PF11838.8 KKK19129.1 - 2.4e-84 283.6 6.5 6.1e-84 282.3 6.5 1.7 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 KKK19129.1 - 1.5e-44 152.4 0.7 3e-43 148.2 0.1 2.5 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain WD40 PF00400.32 KKK19130.1 - 2.1e-05 25.2 14.0 0.025 15.4 0.1 6.2 7 0 0 7 7 7 2 WD domain, G-beta repeat Nup160 PF11715.8 KKK19130.1 - 0.0014 17.4 0.3 0.0041 15.8 0.3 1.7 1 0 0 1 1 1 1 Nucleoporin Nup120/160 Raptor_N PF14538.6 KKK19130.1 - 0.12 12.3 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 Raptor N-terminal CASPase like domain RRM_1 PF00076.22 KKK19136.1 - 4.4e-15 55.2 0.0 7.9e-15 54.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF5486 PF17588.2 KKK19136.1 - 0.17 11.8 0.9 0.37 10.7 0.9 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5486) Ribosomal_L32e PF01655.18 KKK19137.1 - 2.9e-49 166.0 0.6 7.1e-49 164.7 0.6 1.7 1 0 0 1 1 1 1 Ribosomal protein L32 GFO_IDH_MocA PF01408.22 KKK19137.1 - 3.4e-16 60.2 0.0 8.9e-16 58.8 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KKK19137.1 - 0.0014 18.6 0.0 0.0034 17.4 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Sec2p PF06428.11 KKK19138.1 - 3.5e-09 36.5 11.0 3.5e-09 36.5 11.0 2.6 3 0 0 3 3 3 1 GDP/GTP exchange factor Sec2p bZIP_1 PF00170.21 KKK19138.1 - 0.0045 17.1 12.9 0.035 14.2 0.2 3.2 2 1 1 3 3 3 2 bZIP transcription factor Jnk-SapK_ap_N PF09744.9 KKK19138.1 - 0.073 13.3 23.3 0.37 11.0 12.8 2.8 3 0 0 3 3 3 0 JNK_SAPK-associated protein-1 UPF0242 PF06785.11 KKK19138.1 - 0.21 11.7 12.8 2.3 8.3 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus SlyX PF04102.12 KKK19138.1 - 0.41 11.3 0.1 0.41 11.3 0.1 4.0 3 1 1 4 4 4 0 SlyX Vac_Fusion PF02346.16 KKK19138.1 - 0.54 9.9 6.8 3.8 7.2 2.5 2.7 2 0 0 2 2 2 0 Chordopoxvirus multifunctional envelope protein A27 TFIIA PF03153.13 KKK19138.1 - 0.54 10.2 18.7 0.66 9.9 18.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MFS_1 PF07690.16 KKK19139.1 - 6.8e-45 153.5 43.9 3.5e-35 121.6 18.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KKK19139.1 - 2.5e-07 29.4 3.2 7.9e-06 24.4 1.8 3.0 2 1 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family MFS_3 PF05977.13 KKK19139.1 - 6.6e-07 28.1 14.5 3.6e-06 25.7 3.8 2.5 2 0 0 2 2 2 2 Transmembrane secretion effector PUCC PF03209.15 KKK19139.1 - 4.1e-06 26.0 1.7 4.1e-06 26.0 1.7 2.4 2 0 0 2 2 2 1 PUCC protein NAD4L PF06235.11 KKK19139.1 - 0.014 15.4 0.3 0.014 15.4 0.3 2.6 2 0 0 2 2 2 0 NADH dehydrogenase subunit 4L (NAD4L) MFS_4 PF06779.14 KKK19139.1 - 0.016 14.5 28.2 0.37 10.0 1.9 3.9 2 2 2 4 4 4 0 Uncharacterised MFS-type transporter YbfB CTD_bind PF04818.13 KKK19168.1 - 1.3e-11 45.1 0.1 3.5e-11 43.7 0.1 1.8 2 0 0 2 2 2 1 RNA polymerase II-binding domain. DUF2457 PF10446.9 KKK19168.1 - 0.044 12.9 9.5 0.063 12.4 9.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) MIS13 PF08202.11 KKK19170.1 - 1.5e-45 155.8 7.1 4e-44 151.1 7.1 2.2 1 1 0 1 1 1 1 Mis12-Mtw1 protein family Trypan_PARP PF05887.11 KKK19170.1 - 0.015 15.3 14.9 0.015 15.3 14.9 3.2 2 2 1 3 3 3 0 Procyclic acidic repetitive protein (PARP) TSC22 PF01166.18 KKK19170.1 - 0.031 14.6 0.3 0.076 13.3 0.3 1.6 1 0 0 1 1 1 0 TSC-22/dip/bun family DUF3216 PF11505.8 KKK19170.1 - 0.036 14.2 0.8 8.1 6.7 0.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3216) L_lactis_ph-MCP PF06673.11 KKK19170.1 - 0.042 12.9 0.2 0.071 12.1 0.2 1.3 1 0 0 1 1 1 0 Lactococcus lactis bacteriophage major capsid protein DivIC PF04977.15 KKK19170.1 - 0.35 10.7 3.3 0.92 9.3 3.3 1.7 1 0 0 1 1 1 0 Septum formation initiator HAUS6_N PF14661.6 KKK19170.1 - 2.4 7.7 7.5 13 5.3 0.1 2.6 2 1 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus ThrE PF06738.12 KKK19171.1 - 6.3e-76 254.9 17.4 7.9e-71 238.2 3.5 2.3 2 0 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 KKK19171.1 - 1.1e-07 32.1 15.3 1.1e-07 32.1 15.3 2.9 2 1 0 2 2 2 1 Threonine/Serine exporter, ThrE DUF4748 PF15932.5 KKK19173.1 - 0.023 14.5 0.6 0.044 13.5 0.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4748) ERCC3_RAD25_C PF16203.5 KKK19174.1 - 2.9e-124 413.2 0.9 5.7e-124 412.2 0.9 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 KKK19174.1 - 1.3e-35 122.3 0.0 3e-35 121.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KKK19174.1 - 6.6e-15 55.5 0.0 1.4e-14 54.4 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KKK19174.1 - 1.5e-13 51.0 0.1 3.7e-13 49.8 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 KKK19174.1 - 2e-09 36.7 0.0 2.4e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.29 KKK19174.1 - 0.0003 20.6 0.0 0.00062 19.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_34 PF13872.6 KKK19174.1 - 0.00068 18.6 0.0 0.0012 17.8 0.0 1.3 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 DUF4677 PF15726.5 KKK19174.1 - 0.027 14.6 1.0 0.027 14.6 1.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4677) Sugar_tr PF00083.24 KKK19175.1 - 4.3e-84 283.0 10.4 5e-84 282.8 10.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKK19175.1 - 2.1e-33 115.7 25.2 2.8e-33 115.3 25.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 KKK19175.1 - 2.1e-08 33.9 3.0 6.2e-08 32.3 3.0 1.7 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB TRI12 PF06609.13 KKK19175.1 - 0.0017 16.9 1.5 0.0017 16.9 1.5 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 KKK19175.1 - 0.027 12.8 4.1 0.024 12.9 1.5 2.2 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family PS_Dcarbxylase PF02666.15 KKK19176.1 - 3.4e-55 186.7 0.0 5e-55 186.2 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.30 KKK19176.1 - 6e-28 97.2 0.0 6.7e-17 61.7 0.0 2.5 2 0 0 2 2 2 2 C2 domain EF-hand_1 PF00036.32 KKK19176.1 - 0.017 14.7 0.1 0.055 13.0 0.1 2.0 1 0 0 1 1 1 0 EF hand DUF4681 PF15732.5 KKK19176.1 - 0.027 14.7 0.1 0.063 13.5 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4681) EF-hand_5 PF13202.6 KKK19176.1 - 0.064 12.8 0.0 0.17 11.4 0.0 1.8 1 0 0 1 1 1 0 EF hand EF-hand_6 PF13405.6 KKK19176.1 - 0.075 13.0 0.1 0.34 10.9 0.1 2.2 1 0 0 1 1 1 0 EF-hand domain EF-hand_7 PF13499.6 KKK19176.1 - 0.25 11.8 2.2 0.39 11.2 0.6 2.2 2 0 0 2 2 2 0 EF-hand domain pair Hydrophobin PF01185.18 KKK19177.1 - 0.00021 21.8 7.1 0.0004 21.0 7.1 1.5 1 0 0 1 1 1 1 Fungal hydrophobin IBN_N PF03810.19 KKK19194.1 - 6e-14 51.7 1.3 1.5e-13 50.5 0.2 2.4 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.12 KKK19194.1 - 0.0029 17.7 3.4 0.012 15.6 0.1 3.7 4 1 0 4 4 4 1 Exportin 1-like protein AAA PF00004.29 KKK19208.1 - 3.4e-14 53.4 0.1 9e-13 48.8 0.1 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) BCS1_N PF08740.11 KKK19208.1 - 0.00063 19.8 0.2 0.00099 19.1 0.2 1.3 1 0 0 1 1 1 1 BCS1 N terminal AAA_5 PF07728.14 KKK19208.1 - 0.031 14.3 0.0 0.072 13.1 0.0 1.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) ATPase PF06745.13 KKK19208.1 - 0.16 11.3 0.0 0.27 10.6 0.0 1.3 1 0 0 1 1 1 0 KaiC Velvet PF11754.8 KKK19209.1 - 8.3e-58 196.3 0.0 1.8e-55 188.6 0.0 2.1 1 1 0 1 1 1 1 Velvet factor Ribosomal_L12 PF00542.19 KKK19210.1 - 6.2e-20 71.3 10.5 7.9e-19 67.8 8.9 2.2 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 KKK19210.1 - 6.8e-14 51.3 1.9 6.8e-14 51.3 1.9 2.8 3 1 0 3 3 3 1 Ribosomal protein L7/L12 dimerisation domain GHMP_kinases_C PF08544.13 KKK19210.1 - 0.034 14.5 3.1 7 7.1 0.5 3.3 2 2 1 3 3 3 0 GHMP kinases C terminal SpoVIF PF14069.6 KKK19210.1 - 0.038 13.8 2.8 0.052 13.3 1.0 2.1 2 1 0 2 2 2 0 Stage VI sporulation protein F HisG_C PF08029.11 KKK19210.1 - 0.048 13.8 0.1 0.13 12.4 0.1 1.9 1 0 0 1 1 1 0 HisG, C-terminal domain FliG_N PF14842.6 KKK19210.1 - 0.053 14.1 1.2 0.081 13.5 0.4 1.7 2 0 0 2 2 2 0 FliG N-terminal domain Methyltransf_34 PF11312.8 KKK19210.1 - 0.13 11.5 0.0 0.15 11.3 0.0 1.1 1 0 0 1 1 1 0 Putative SAM-dependent methyltransferase DUF1682 PF07946.14 KKK19211.1 - 4.5e-111 371.1 5.1 5.3e-111 370.9 5.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) NAD_binding_10 PF13460.6 KKK19212.1 - 5.1e-06 26.5 0.0 4.2e-05 23.5 0.0 2.3 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KKK19212.1 - 2.2e-05 24.0 0.0 4.5e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KKK19212.1 - 6.2e-05 22.1 0.0 0.00012 21.2 0.0 1.5 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 KKK19212.1 - 0.003 17.0 0.0 0.0051 16.3 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.17 KKK19212.1 - 0.045 12.8 0.0 0.21 10.7 0.0 1.9 2 0 0 2 2 2 0 RmlD substrate binding domain KR PF08659.10 KKK19212.1 - 0.045 13.7 0.0 0.078 12.9 0.0 1.3 1 0 0 1 1 1 0 KR domain NAD_binding_4 PF07993.12 KKK19212.1 - 0.07 12.3 0.0 1.3 8.1 0.0 2.3 2 0 0 2 2 2 0 Male sterility protein SYF2 PF08231.12 KKK19213.1 - 9.6e-57 191.8 16.0 9.6e-57 191.8 16.0 2.0 2 0 0 2 2 2 1 SYF2 splicing factor gag_pre-integrs PF13976.6 KKK19214.1 - 0.13 12.2 0.1 0.3 11.0 0.1 1.5 1 0 0 1 1 1 0 GAG-pre-integrase domain IDO PF01231.18 KKK19215.1 - 1.8e-155 518.0 0.0 2e-155 517.8 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase YEATS PF03366.16 KKK19216.1 - 8.3e-37 125.0 1.8 1.3e-36 124.4 1.8 1.3 1 0 0 1 1 1 1 YEATS family M16C_assoc PF08367.11 KKK19216.1 - 0.05 12.7 2.8 0.072 12.2 2.8 1.2 1 0 0 1 1 1 0 Peptidase M16C associated DUF334 PF03904.13 KKK19216.1 - 0.28 10.7 1.4 0.56 9.7 1.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF334) COX7a PF02238.15 KKK19217.1 - 9.5e-23 80.4 4.1 1.2e-22 80.0 4.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VII Aminotran_5 PF00266.19 KKK19218.1 - 7.8e-07 28.4 0.0 2.7e-06 26.6 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 KKK19218.1 - 0.0034 16.7 0.0 0.0048 16.2 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family PX PF00787.24 KKK19220.1 - 3.8e-13 49.4 0.0 7e-13 48.5 0.0 1.4 1 0 0 1 1 1 1 PX domain SH3_1 PF00018.28 KKK19220.1 - 4.5e-12 45.4 0.0 1.7e-11 43.6 0.0 2.0 2 0 0 2 2 2 1 SH3 domain PB1 PF00564.24 KKK19220.1 - 5.2e-08 32.7 0.5 1.1e-07 31.7 0.5 1.5 1 0 0 1 1 1 1 PB1 domain SH3_9 PF14604.6 KKK19220.1 - 2.4e-05 24.1 0.0 5.3e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KKK19220.1 - 0.16 11.7 0.0 1.1 9.0 0.0 2.3 2 0 0 2 2 2 0 Variant SH3 domain AFG1_ATPase PF03969.16 KKK19221.1 - 7.9e-82 275.0 0.1 6.8e-63 212.7 0.0 3.2 3 0 0 3 3 3 3 AFG1-like ATPase Cation_efflux PF01545.21 KKK19221.1 - 2.1e-39 135.4 0.2 6.1e-39 133.8 0.1 1.7 2 0 0 2 2 2 1 Cation efflux family TniB PF05621.11 KKK19221.1 - 0.0025 17.3 0.0 2.5 7.5 0.0 2.4 2 0 0 2 2 2 2 Bacterial TniB protein AAA_16 PF13191.6 KKK19221.1 - 0.0028 18.1 0.0 1.2 9.5 0.0 2.8 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KKK19221.1 - 0.0034 17.7 0.0 0.12 12.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 KKK19221.1 - 0.0042 17.1 0.0 0.0085 16.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain BPD_transp_2 PF02653.16 KKK19221.1 - 0.02 14.1 0.4 0.041 13.0 0.4 1.5 1 0 0 1 1 1 0 Branched-chain amino acid transport system / permease component AAA PF00004.29 KKK19221.1 - 0.02 15.4 0.0 0.051 14.0 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KKK19221.1 - 0.059 13.4 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 KKK19221.1 - 0.11 12.8 0.0 0.36 11.2 0.0 2.0 1 0 0 1 1 1 0 RNA helicase Bac_DnaA PF00308.18 KKK19221.1 - 0.16 11.8 0.0 8.9 6.1 0.0 2.4 2 0 0 2 2 2 0 Bacterial dnaA protein Rhodanese PF00581.20 KKK19222.1 - 1.7e-10 41.3 0.0 2.4e-10 40.9 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain TnsD PF15978.5 KKK19222.1 - 0.26 10.3 0.0 0.32 9.9 0.0 1.1 1 0 0 1 1 1 0 Tn7-like transposition protein D RabGAP-TBC PF00566.18 KKK19223.1 - 9.8e-23 80.9 0.2 1.4e-22 80.5 0.2 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain CaKB PF03185.15 KKK19223.1 - 0.1 12.3 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Calcium-activated potassium channel, beta subunit GTP_EFTU PF00009.27 KKK19224.1 - 1.6e-35 122.4 0.0 7.2e-35 120.3 0.0 2.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 KKK19224.1 - 2e-19 69.6 0.1 6.2e-19 68.1 0.1 1.9 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.25 KKK19224.1 - 3.9e-11 43.2 2.5 1.2e-09 38.4 0.0 3.7 3 0 0 3 3 3 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.6 KKK19224.1 - 4.3e-08 33.0 0.1 1.5e-07 31.2 0.1 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.23 KKK19224.1 - 2e-06 27.9 0.2 2.3e-05 24.4 0.0 2.9 3 0 0 3 3 3 1 50S ribosome-binding GTPase Roc PF08477.13 KKK19224.1 - 0.0019 18.4 0.0 0.0057 16.9 0.0 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 KKK19224.1 - 0.013 15.3 0.0 0.042 13.6 0.0 2.0 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein RsgA_GTPase PF03193.16 KKK19224.1 - 0.046 13.6 0.2 0.6 10.0 0.2 2.8 2 1 0 2 2 2 0 RsgA GTPase Fe-ADH_2 PF13685.6 KKK19224.1 - 0.67 9.6 2.6 1.8 8.2 2.6 1.7 1 0 0 1 1 1 0 Iron-containing alcohol dehydrogenase MMS1_N PF10433.9 KKK19225.1 - 1.9e-106 356.6 0.0 2.7e-106 356.1 0.0 1.3 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term TrkH PF02386.16 KKK19226.1 - 2.1e-146 488.3 2.8 2.1e-146 488.3 2.8 2.1 2 0 0 2 2 2 2 Cation transport protein PH PF00169.29 KKK19227.1 - 0.00083 19.8 1.1 0.0018 18.8 1.1 1.5 1 0 0 1 1 1 1 PH domain RmlD_sub_bind PF04321.17 KKK19228.1 - 2.6e-54 184.3 0.0 3.4e-54 183.9 0.0 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 KKK19228.1 - 2.8e-20 72.8 0.0 3.7e-20 72.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KKK19228.1 - 2e-09 37.0 0.2 2e-07 30.5 0.0 2.7 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 KKK19228.1 - 2.8e-09 36.5 0.1 1.4e-07 31.0 0.0 2.2 2 0 0 2 2 2 1 Male sterility protein 3Beta_HSD PF01073.19 KKK19228.1 - 7.6e-09 35.0 0.0 4.7e-08 32.4 0.0 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KKK19228.1 - 2.2e-08 33.9 0.0 4.3e-08 32.9 0.0 1.6 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase KR PF08659.10 KKK19228.1 - 0.0077 16.2 0.2 6.8 6.6 0.2 2.9 2 1 1 3 3 3 2 KR domain Glyco_trans_2_3 PF13632.6 KKK19229.1 - 1.2e-35 123.3 6.6 1.2e-35 123.3 6.6 1.9 1 1 1 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KKK19229.1 - 0.0004 20.4 0.0 0.0023 17.9 0.0 1.9 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KKK19229.1 - 0.019 14.8 0.0 0.062 13.1 0.0 1.9 1 1 0 1 1 1 0 Glycosyl transferase family 2 Tir_receptor_C PF07489.11 KKK19229.1 - 0.1 12.6 0.2 0.17 11.8 0.2 1.3 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus F-box-like PF12937.7 KKK19230.1 - 0.019 14.8 5.0 0.026 14.4 1.5 2.7 2 0 0 2 2 2 0 F-box-like F-box PF00646.33 KKK19230.1 - 0.037 13.9 1.6 0.18 11.7 1.6 2.2 1 1 0 1 1 1 0 F-box domain Sulf_transp PF04143.14 KKK19231.1 - 3.7e-07 30.0 7.1 6.6e-07 29.2 0.3 2.6 2 1 1 3 3 3 3 Sulphur transport FR47 PF08445.10 KKK19232.1 - 0.043 13.8 0.0 0.061 13.3 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein p450 PF00067.22 KKK19233.1 - 0.00047 19.0 0.3 0.00097 18.0 0.3 1.5 1 0 0 1 1 1 1 Cytochrome P450 Seryl_tRNA_N PF02403.22 KKK19233.1 - 0.0064 16.7 12.3 0.068 13.4 4.5 3.0 1 1 0 2 2 2 2 Seryl-tRNA synthetase N-terminal domain V-SNARE PF05008.15 KKK19233.1 - 0.012 16.0 4.8 0.041 14.2 4.8 1.9 1 0 0 1 1 1 0 Vesicle transport v-SNARE protein N-terminus FlaC_arch PF05377.11 KKK19233.1 - 0.026 14.9 0.9 0.026 14.9 0.9 3.1 3 0 0 3 3 2 0 Flagella accessory protein C (FlaC) Paralemmin PF03285.15 KKK19233.1 - 0.052 13.1 7.6 0.04 13.5 6.1 1.5 1 1 0 1 1 1 0 Paralemmin COG5 PF10392.9 KKK19233.1 - 0.14 12.4 8.1 0.023 14.9 3.9 2.0 2 0 0 2 2 1 0 Golgi transport complex subunit 5 CLZ PF16526.5 KKK19233.1 - 0.14 12.5 6.9 0.12 12.7 2.7 2.7 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels ABATE PF07336.11 KKK19233.1 - 0.16 12.7 4.2 0.1 13.3 0.6 2.5 3 1 0 3 3 2 0 Putative stress-induced transcription regulator Spc24 PF08286.11 KKK19233.1 - 0.23 11.7 7.7 1.1 9.5 3.0 2.9 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 TPR_MLP1_2 PF07926.12 KKK19233.1 - 0.26 11.3 22.2 0.52 10.4 8.1 3.1 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein DUF1664 PF07889.12 KKK19233.1 - 0.67 10.0 6.3 0.53 10.3 2.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Laminin_II PF06009.12 KKK19233.1 - 1 9.4 8.7 0.8 9.7 3.0 2.7 3 0 0 3 3 3 0 Laminin Domain II DUF3450 PF11932.8 KKK19233.1 - 1.4 8.1 13.7 0.68 9.2 4.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Phage_GP20 PF06810.11 KKK19233.1 - 2.5 7.9 9.3 0.29 10.9 0.8 2.8 2 1 1 3 3 3 0 Phage minor structural protein GP20 DivIC PF04977.15 KKK19233.1 - 3.3 7.5 6.5 12 5.8 1.3 3.0 2 0 0 2 2 2 0 Septum formation initiator Allexi_40kDa PF05549.11 KKK19233.1 - 6 6.3 8.8 3.2 7.2 5.1 2.1 2 1 0 2 2 2 0 Allexivirus 40kDa protein Filament PF00038.21 KKK19233.1 - 6.3 6.3 24.4 0.067 12.8 8.0 3.1 3 1 1 4 4 4 0 Intermediate filament protein LMBR1 PF04791.16 KKK19233.1 - 6.7 5.5 5.6 9.1 5.1 5.6 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF724 PF05266.14 KKK19233.1 - 8.3 6.2 12.1 1.3 8.8 5.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF724) E2F_CC-MB PF16421.5 KKK19233.1 - 9.8 6.6 7.3 35 4.8 0.0 3.4 3 0 0 3 3 3 0 E2F transcription factor CC-MB domain Peptidase_M28 PF04389.17 KKK19234.1 - 2.5e-29 102.4 0.0 4.5e-29 101.6 0.0 1.3 1 1 0 1 1 1 1 Peptidase family M28 Sec7 PF01369.20 KKK19235.1 - 3.1e-32 111.7 0.0 5e-32 111.1 0.0 1.2 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.6 KKK19235.1 - 2.6e-08 34.2 0.2 5.7e-08 33.2 0.2 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 KKK19235.1 - 1.4e-05 25.6 0.0 5.2e-05 23.7 0.0 2.1 1 0 0 1 1 1 1 PH domain Zip PF02535.22 KKK19236.1 - 2.5e-23 82.9 1.7 2.5e-23 82.9 1.7 2.0 2 1 0 2 2 2 1 ZIP Zinc transporter GRDP-like PF07173.12 KKK19250.1 - 5.6e-18 66.0 2.1 1.1e-13 52.0 0.1 2.6 2 0 0 2 2 2 2 Glycine-rich domain-containing protein-like Pea-VEAacid PF08111.11 KKK19250.1 - 0.78 10.2 3.8 8.4 7.0 0.2 2.7 2 0 0 2 2 2 0 Pea-VEAacid family Fungal_trans PF04082.18 KKK19251.1 - 7.9e-10 38.2 0.8 1.2e-09 37.6 0.8 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK19251.1 - 1.4e-06 28.3 10.4 3.2e-06 27.2 10.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mst1_SARAH PF11629.8 KKK19251.1 - 0.16 12.1 2.0 19 5.4 0.4 2.8 2 0 0 2 2 2 0 C terminal SARAH domain of Mst1 F-box-like PF12937.7 KKK19252.1 - 0.005 16.7 0.2 0.013 15.4 0.2 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KKK19252.1 - 0.014 15.3 0.4 0.028 14.3 0.4 1.6 1 0 0 1 1 1 0 F-box domain Fungal_trans PF04082.18 KKK19253.1 - 4.6e-15 55.4 0.0 9.5e-15 54.3 0.0 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK19253.1 - 1.6e-06 28.1 7.0 3.6e-06 27.0 7.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PLDc PF00614.22 KKK19255.1 - 4.3e-15 55.2 0.2 2.7e-07 30.5 0.1 2.7 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 KKK19255.1 - 1.1e-12 48.0 0.1 2.4e-06 27.5 0.0 3.1 3 1 0 3 3 3 2 PLD-like domain PX PF00787.24 KKK19255.1 - 1.9e-07 31.1 0.2 8.3e-07 29.0 0.0 2.3 2 0 0 2 2 2 1 PX domain MR_MLE_C PF13378.6 KKK19256.1 - 4e-40 137.7 0.0 5.2e-40 137.3 0.0 1.1 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 KKK19256.1 - 1.4e-10 41.4 0.0 2.4e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Fungal_trans PF04082.18 KKK19257.1 - 7.3e-24 84.2 0.0 1e-23 83.7 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Trimer_CC PF08954.11 KKK19257.1 - 0.47 10.0 5.1 0.28 10.8 0.4 2.6 2 0 0 2 2 2 0 Trimerisation motif Pkinase PF00069.25 KKK19258.1 - 4.2e-31 108.3 0.0 6.5e-31 107.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK19258.1 - 8.3e-24 84.3 0.0 1.4e-23 83.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase HPIP PF15226.6 KKK19259.1 - 0.016 15.6 2.7 0.016 15.6 2.7 2.1 3 0 0 3 3 3 0 HCF-1 beta-propeller-interacting protein family Fungal_trans PF04082.18 KKK19260.1 - 1.5e-19 70.1 0.3 3e-19 69.1 0.0 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK19260.1 - 1.7e-10 40.8 11.1 3.4e-10 39.9 11.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CBFD_NFYB_HMF PF00808.23 KKK19261.1 - 2.9e-29 101.1 1.0 4.1e-29 100.6 1.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KKK19261.1 - 1.2e-07 32.1 0.5 1.8e-07 31.6 0.5 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.16 KKK19261.1 - 0.00091 19.2 0.0 0.0013 18.7 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Bromo_TP PF07524.13 KKK19261.1 - 0.0016 18.4 0.1 0.0029 17.6 0.1 1.4 1 0 0 1 1 1 1 Bromodomain associated CENP-T_C PF15511.6 KKK19261.1 - 0.0053 16.9 0.0 0.0074 16.4 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TFIID_20kDa PF03847.13 KKK19261.1 - 0.059 13.9 0.0 0.11 13.0 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A Fungal_trans PF04082.18 KKK19262.1 - 1.9e-18 66.5 0.1 1.8e-17 63.2 0.0 2.4 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK19262.1 - 6.4e-10 39.0 10.2 1e-09 38.4 10.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Abhydrolase_1 PF00561.20 KKK19263.1 - 3e-21 76.2 0.0 5.8e-20 72.0 0.0 2.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KKK19263.1 - 2.6e-17 62.9 0.0 3e-16 59.4 0.0 2.5 3 0 0 3 3 3 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KKK19263.1 - 8.1e-16 59.3 2.7 6.4e-14 53.1 2.7 2.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF915 PF06028.11 KKK19263.1 - 2e-06 27.4 0.0 3.4e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Esterase PF00756.20 KKK19263.1 - 8.4e-06 25.6 0.0 1.9e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Putative esterase PGAP1 PF07819.13 KKK19263.1 - 0.0025 17.6 0.0 0.027 14.2 0.0 2.1 2 0 0 2 2 2 1 PGAP1-like protein Chlorophyllase2 PF12740.7 KKK19263.1 - 0.0053 15.7 0.0 0.0088 15.0 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_2 PF02230.16 KKK19263.1 - 0.031 14.1 0.0 0.47 10.2 0.0 2.4 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase LIDHydrolase PF10230.9 KKK19263.1 - 0.044 13.3 0.0 0.073 12.6 0.0 1.3 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Thioesterase PF00975.20 KKK19263.1 - 0.048 13.8 0.1 0.13 12.3 0.1 1.8 1 1 0 1 1 1 0 Thioesterase domain Abhydrolase_3 PF07859.13 KKK19263.1 - 0.058 13.2 0.1 0.17 11.7 0.0 1.8 2 0 0 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_5 PF12695.7 KKK19263.1 - 0.077 12.8 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family p450 PF00067.22 KKK19264.1 - 1.4e-56 192.2 0.0 2e-56 191.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DNA_ligase_OB PF03120.16 KKK19264.1 - 0.23 11.4 0.0 0.49 10.3 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent DNA ligase OB-fold domain MarB PF13999.6 KKK19265.1 - 0.35 10.8 1.8 1.8 8.5 0.2 2.6 2 1 1 3 3 3 0 MarB protein Spo7 PF03907.13 KKK19266.1 - 2.7e-89 298.4 0.0 3.7e-89 298.0 0.0 1.2 1 0 0 1 1 1 1 Spo7-like protein TatD_DNase PF01026.21 KKK19267.1 - 3.9e-33 114.9 0.0 7.4e-33 114.0 0.0 1.4 1 1 0 1 1 1 1 TatD related DNase DAD PF02109.16 KKK19268.1 - 1.4e-31 109.0 0.5 8.7e-30 103.2 0.5 2.3 1 1 0 1 1 1 1 DAD family HA2 PF04408.23 KKK19269.1 - 4e-20 72.1 2.2 1e-19 70.8 0.0 2.7 3 0 0 3 3 3 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KKK19269.1 - 1.2e-16 60.8 0.0 5.1e-16 58.8 0.0 2.1 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KKK19269.1 - 9.4e-16 58.1 0.0 2.3e-15 56.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KKK19269.1 - 1.8e-06 27.8 0.0 4.5e-06 26.6 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KKK19269.1 - 1.6e-05 25.2 0.0 4.4e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 KKK19269.1 - 8e-05 22.0 0.0 0.00014 21.2 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) T2SSE PF00437.20 KKK19269.1 - 0.001 18.2 0.1 0.0089 15.1 0.0 2.4 3 0 0 3 3 3 1 Type II/IV secretion system protein AAA_30 PF13604.6 KKK19269.1 - 0.0014 18.4 0.0 0.0032 17.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 KKK19269.1 - 0.0025 17.5 0.2 0.008 15.8 0.2 1.9 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_19 PF13245.6 KKK19269.1 - 0.0033 17.8 0.1 0.011 16.0 0.1 1.9 2 0 0 2 2 2 1 AAA domain ATPase PF06745.13 KKK19269.1 - 0.0065 15.8 0.0 0.013 14.9 0.0 1.4 1 0 0 1 1 1 1 KaiC AAA_24 PF13479.6 KKK19269.1 - 0.013 15.3 0.0 0.024 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KKK19269.1 - 0.014 15.4 0.2 0.087 12.9 0.2 2.2 1 1 0 1 1 1 0 AAA domain Flavi_DEAD PF07652.14 KKK19269.1 - 0.015 15.3 0.0 0.028 14.4 0.0 1.4 1 0 0 1 1 1 0 Flavivirus DEAD domain ResIII PF04851.15 KKK19269.1 - 0.023 14.7 0.0 7.2 6.6 0.0 2.5 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_33 PF13671.6 KKK19269.1 - 0.053 13.7 0.8 0.37 10.9 0.0 2.6 2 1 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KKK19269.1 - 0.1 13.1 0.1 0.36 11.3 0.0 2.0 2 0 0 2 2 1 0 ABC transporter AAA_7 PF12775.7 KKK19269.1 - 0.12 11.8 0.0 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_16 PF13191.6 KKK19269.1 - 0.13 12.6 0.0 0.35 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain cobW PF02492.19 KKK19269.1 - 0.18 11.4 0.2 1.5 8.4 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF5401 PF17380.2 KKK19269.1 - 9.1 4.2 14.0 0.77 7.8 8.5 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5401) Prefoldin_2 PF01920.20 KKK19270.1 - 2.5e-26 91.7 8.1 3.4e-26 91.3 8.1 1.1 1 0 0 1 1 1 1 Prefoldin subunit ATPase PF06745.13 KKK19270.1 - 0.0037 16.6 0.5 0.14 11.5 0.1 2.0 1 1 1 2 2 2 1 KaiC Tho2 PF11262.8 KKK19270.1 - 0.019 14.2 1.0 0.03 13.5 1.0 1.4 1 1 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 BRE PF06113.12 KKK19270.1 - 0.036 12.9 0.0 0.052 12.4 0.0 1.3 1 0 0 1 1 1 0 Brain and reproductive organ-expressed protein (BRE) ATP-synt_D PF01813.17 KKK19270.1 - 0.05 13.4 1.8 5.1 6.9 0.2 2.1 2 0 0 2 2 2 0 ATP synthase subunit D Prefoldin PF02996.17 KKK19270.1 - 0.064 13.2 7.2 0.57 10.1 0.2 2.2 1 1 0 2 2 2 0 Prefoldin subunit Troponin PF00992.20 KKK19270.1 - 0.086 13.1 4.7 2 8.7 0.1 2.1 2 0 0 2 2 2 0 Troponin p25-alpha PF05517.12 KKK19270.1 - 0.16 12.1 1.5 1.7 8.8 0.2 2.0 2 0 0 2 2 2 0 p25-alpha OmpH PF03938.14 KKK19270.1 - 0.35 11.2 10.1 4 7.8 5.4 2.1 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) ZnuA PF01297.17 KKK19270.1 - 0.47 9.8 3.2 1 8.7 1.4 1.9 2 0 0 2 2 2 0 Zinc-uptake complex component A periplasmic RF-1 PF00472.20 KKK19270.1 - 1 9.3 5.8 0.68 9.9 1.2 2.1 2 0 0 2 2 2 0 RF-1 domain SRP68 PF16969.5 KKK19271.1 - 3.9e-192 640.2 0.1 4.5e-192 640.0 0.1 1.0 1 0 0 1 1 1 1 RNA-binding signal recognition particle 68 SEN1_N PF12726.7 KKK19271.1 - 0.21 9.7 0.4 0.37 8.9 0.1 1.5 2 0 0 2 2 2 0 SEN1 N terminal Ribosomal_60s PF00428.19 KKK19271.1 - 5.3 7.7 18.0 0.11 13.1 6.2 2.9 3 0 0 3 3 3 0 60s Acidic ribosomal protein PPR_2 PF13041.6 KKK19272.1 - 1.9e-14 53.6 10.1 3e-08 33.7 0.2 7.0 7 1 2 9 9 9 4 PPR repeat family PPR PF01535.20 KKK19272.1 - 7.4e-14 50.9 4.1 0.0083 16.3 0.2 8.8 9 0 0 9 9 9 2 PPR repeat PPR_3 PF13812.6 KKK19272.1 - 2.3e-10 40.4 2.2 0.00084 19.4 0.0 5.7 5 1 3 8 8 8 3 Pentatricopeptide repeat domain PPR_long PF17177.4 KKK19272.1 - 2e-07 30.6 0.1 1.7e-06 27.6 0.0 2.5 2 1 0 3 3 3 1 Pentacotripeptide-repeat region of PRORP TPR_14 PF13428.6 KKK19272.1 - 0.00054 20.6 9.1 12 7.1 0.1 7.4 7 1 1 8 8 8 1 Tetratricopeptide repeat PPR_1 PF12854.7 KKK19272.1 - 0.015 15.0 0.2 34 4.3 0.0 4.9 5 0 0 5 5 5 0 PPR repeat Wzy_C_2 PF11846.8 KKK19272.1 - 0.13 12.2 0.2 0.52 10.2 0.1 2.1 2 0 0 2 2 2 0 Virulence factor membrane-bound polymerase, C-terminal TPR_6 PF13174.6 KKK19272.1 - 0.3 11.8 1.3 47 4.9 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat MCM PF00493.23 KKK19273.1 - 1.9e-96 321.5 0.1 3.2e-96 320.7 0.1 1.4 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KKK19273.1 - 2.4e-31 108.2 0.0 4.5e-31 107.3 0.0 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KKK19273.1 - 3.5e-23 81.8 1.9 9.7e-23 80.4 1.9 1.8 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KKK19273.1 - 1.5e-12 48.0 0.0 6e-12 46.1 0.0 2.1 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.21 KKK19273.1 - 5.1e-06 26.0 0.0 5e-05 22.8 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 KKK19273.1 - 0.0053 16.6 0.0 0.012 15.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Metallophos PF00149.28 KKK19281.1 - 7.3e-37 127.8 0.1 1.1e-36 127.2 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KKK19281.1 - 9.8e-17 61.1 0.0 1.7e-16 60.4 0.0 1.4 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain TRAP_alpha PF03896.16 KKK19282.1 - 0.2 10.8 0.0 0.27 10.4 0.0 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Memo PF01875.17 KKK19283.1 - 1.8e-64 217.5 0.0 2.2e-64 217.3 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein CENP-B_dimeris PF09026.10 KKK19284.1 - 0.38 11.2 27.2 1.9 8.9 0.2 3.6 3 0 0 3 3 3 0 Centromere protein B dimerisation domain Med3 PF11593.8 KKK19284.1 - 5.7 6.0 17.0 2.1 7.5 0.5 2.2 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal LSM PF01423.22 KKK19285.1 - 1.7e-08 34.0 0.0 2.2e-08 33.7 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KKK19285.1 - 0.073 13.2 0.0 0.089 12.9 0.0 1.4 1 1 0 1 1 1 0 Ataxin 2 SM domain Pkinase PF00069.25 KKK19286.1 - 1.3e-25 90.3 0.0 8.3e-25 87.6 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK19286.1 - 3.8e-09 36.2 0.0 5.9e-08 32.3 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase DUF3435 PF11917.8 KKK19286.1 - 0.00065 18.8 0.0 0.00085 18.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) Pkinase_fungal PF17667.1 KKK19286.1 - 0.11 11.3 0.0 2.2 7.0 0.0 2.2 2 0 0 2 2 2 0 Fungal protein kinase AA_permease PF00324.21 KKK19287.1 - 8.8e-139 463.2 36.1 1e-138 463.0 36.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KKK19287.1 - 1.9e-36 125.8 39.8 2.4e-36 125.5 39.8 1.1 1 0 0 1 1 1 1 Amino acid permease Aldose_epim PF01263.20 KKK19288.1 - 2.2e-40 138.8 0.0 2.6e-40 138.6 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase Glyco_hydro_65C PF03633.15 KKK19288.1 - 0.057 13.3 0.2 0.13 12.2 0.2 1.6 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, C-terminal domain zf-RING_2 PF13639.6 KKK19289.1 - 4.3e-14 52.6 4.3 7.4e-14 51.8 4.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KKK19289.1 - 1.5e-10 40.7 4.3 2.9e-10 39.8 4.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KKK19289.1 - 2.4e-10 39.9 2.0 5.6e-10 38.8 2.0 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 KKK19289.1 - 3.5e-09 36.4 2.8 6.3e-09 35.6 2.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KKK19289.1 - 1.7e-08 34.4 1.6 7.9e-08 32.2 1.4 2.3 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 KKK19289.1 - 2.8e-08 33.6 3.2 5.3e-08 32.7 3.2 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KKK19289.1 - 6e-06 26.0 1.9 1.1e-05 25.2 1.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KKK19289.1 - 6.2e-06 26.4 8.0 6.2e-06 26.4 8.0 2.4 2 1 0 2 2 1 1 RING-H2 zinc finger domain Zn_ribbon_17 PF17120.5 KKK19289.1 - 2.4e-05 23.9 2.8 4.1e-05 23.1 2.8 1.3 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 KKK19289.1 - 4.7e-05 23.2 4.1 9.9e-05 22.1 4.1 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KKK19289.1 - 5.9e-05 23.1 3.9 5.9e-05 23.1 3.9 1.9 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING ANAPC_CDC26 PF10471.9 KKK19289.1 - 0.00025 21.8 4.5 0.00056 20.7 4.5 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex APC subunit CDC26 FANCL_C PF11793.8 KKK19289.1 - 0.0018 18.4 3.4 0.0067 16.6 3.4 2.0 1 1 0 1 1 1 1 FANCL C-terminal domain RINGv PF12906.7 KKK19289.1 - 0.002 18.2 1.3 0.0055 16.8 1.3 1.8 1 1 0 1 1 1 1 RING-variant domain SARAF PF06682.12 KKK19289.1 - 0.0023 17.6 0.7 0.003 17.3 0.7 1.1 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis Rtf2 PF04641.12 KKK19289.1 - 0.003 17.0 0.4 0.089 12.1 0.0 2.0 2 0 0 2 2 2 1 Rtf2 RING-finger PHD PF00628.29 KKK19289.1 - 0.0046 16.8 2.3 0.011 15.7 2.3 1.6 1 0 0 1 1 1 1 PHD-finger zf-RING_4 PF14570.6 KKK19289.1 - 0.0059 16.4 4.0 0.011 15.5 4.0 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain TFIIA PF03153.13 KKK19289.1 - 0.0064 16.5 4.8 0.0073 16.3 4.8 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Zf_RING PF16744.5 KKK19289.1 - 0.0079 16.3 2.0 0.0079 16.3 2.0 1.9 2 1 0 2 2 1 1 KIAA1045 RING finger Spt20 PF12090.8 KKK19289.1 - 0.012 15.2 9.2 0.017 14.8 9.2 1.2 1 0 0 1 1 1 0 Spt20 family Chordopox_A13L PF05961.11 KKK19289.1 - 0.015 15.5 1.0 0.96 9.7 0.5 2.3 2 0 0 2 2 2 0 Chordopoxvirus A13L protein RCR PF12273.8 KKK19289.1 - 0.022 15.4 0.3 0.033 14.9 0.3 1.4 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red zf-RING-like PF08746.11 KKK19289.1 - 0.024 14.9 2.2 0.063 13.6 2.2 1.8 1 1 0 1 1 1 0 RING-like domain zf-ANAPC11 PF12861.7 KKK19289.1 - 0.025 14.6 4.4 0.025 14.6 4.4 2.4 2 1 0 2 2 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF2722 PF10846.8 KKK19289.1 - 0.025 13.5 6.6 0.033 13.1 6.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Prok-RING_1 PF14446.6 KKK19289.1 - 0.22 11.5 3.4 0.45 10.5 0.6 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Headcase PF16002.5 KKK19289.1 - 0.38 10.2 2.9 4.4 6.7 0.1 2.5 2 1 0 2 2 2 0 Headcase protein MFS_Mycoplasma PF07672.13 KKK19289.1 - 0.45 9.8 2.7 0.31 10.3 0.3 1.7 1 1 1 2 2 2 0 Mycoplasma MFS transporter Thioredoxin_4 PF13462.6 KKK19289.1 - 0.46 10.6 6.1 0.15 12.2 1.3 2.1 2 0 0 2 2 2 0 Thioredoxin zf-C3H2C3 PF17122.5 KKK19289.1 - 0.52 10.4 4.2 1.6 8.8 4.2 1.9 1 1 0 1 1 1 0 Zinc-finger Med3 PF11593.8 KKK19289.1 - 7.8 5.6 12.5 11 5.1 12.5 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal ABC_membrane PF00664.23 KKK19290.1 - 4.2e-76 256.2 24.1 9.8e-46 156.6 7.8 3.1 3 0 0 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.27 KKK19290.1 - 1.7e-56 190.5 0.0 1.4e-28 100.1 0.0 2.8 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KKK19290.1 - 1.4e-18 67.2 1.3 1.6e-07 31.0 0.0 4.3 3 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain Polysacc_synt_4 PF04669.13 KKK19290.1 - 1e-15 57.8 1.0 1.1e-14 54.5 1.0 2.5 1 1 0 1 1 1 1 Polysaccharide biosynthesis AAA_21 PF13304.6 KKK19290.1 - 3.4e-09 36.9 0.3 0.074 12.8 0.2 4.3 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KKK19290.1 - 1.3e-07 31.3 3.2 0.0092 15.7 0.5 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 KKK19290.1 - 4.3e-07 30.3 1.9 0.036 14.4 0.0 4.8 6 0 0 6 6 4 2 AAA domain AAA_16 PF13191.6 KKK19290.1 - 9.3e-06 26.1 0.2 0.031 14.7 0.1 3.1 2 1 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.6 KKK19290.1 - 2.5e-05 23.9 0.0 0.85 9.2 0.0 3.6 3 0 0 3 3 3 2 AAA domain RsgA_GTPase PF03193.16 KKK19290.1 - 7.9e-05 22.6 0.2 0.49 10.3 0.0 2.9 3 0 0 3 3 3 2 RsgA GTPase MMR_HSR1 PF01926.23 KKK19290.1 - 0.00012 22.2 0.1 0.75 9.9 0.0 2.8 2 1 0 2 2 2 2 50S ribosome-binding GTPase AAA_15 PF13175.6 KKK19290.1 - 0.00037 20.3 1.8 1.3 8.7 0.0 3.2 3 0 0 3 3 3 2 AAA ATPase domain AAA_23 PF13476.6 KKK19290.1 - 0.00044 20.8 0.4 0.74 10.3 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 KKK19290.1 - 0.0008 20.0 0.0 1.8 9.1 0.0 3.4 3 0 0 3 3 3 1 AAA domain ABC_ATPase PF09818.9 KKK19290.1 - 0.00092 18.1 1.8 0.78 8.5 0.0 3.7 4 0 0 4 4 4 1 Predicted ATPase of the ABC class AAA_33 PF13671.6 KKK19290.1 - 0.0042 17.3 0.0 3.2 7.9 0.0 3.0 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.17 KKK19290.1 - 0.0047 17.0 4.2 0.12 12.5 0.1 3.1 3 0 0 3 3 3 1 Helicase HerA, central domain AAA_5 PF07728.14 KKK19290.1 - 0.019 15.0 0.1 7.3 6.6 0.0 2.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) DUF3987 PF13148.6 KKK19290.1 - 0.022 13.8 0.1 2.3 7.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) SbcCD_C PF13558.6 KKK19290.1 - 0.04 14.1 0.0 8.3 6.7 0.0 3.0 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit APS_kinase PF01583.20 KKK19290.1 - 0.042 13.7 0.3 12 5.7 0.0 2.7 2 0 0 2 2 2 0 Adenylylsulphate kinase ATPase PF06745.13 KKK19290.1 - 0.055 12.8 9.1 5.2 6.4 0.5 3.8 4 0 0 4 4 4 0 KaiC NB-ARC PF00931.22 KKK19290.1 - 0.057 12.6 0.4 1.2 8.3 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain AAA_24 PF13479.6 KKK19290.1 - 0.059 13.1 1.2 12 5.5 0.0 2.8 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KKK19290.1 - 0.06 13.3 0.4 15 5.4 0.6 2.8 2 0 0 2 2 2 0 NACHT domain Sigma54_activat PF00158.26 KKK19290.1 - 0.084 12.6 0.0 10 5.8 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_30 PF13604.6 KKK19290.1 - 0.088 12.5 0.1 8.7 6.0 0.0 2.9 3 0 0 3 3 3 0 AAA domain FtsK_SpoIIIE PF01580.18 KKK19290.1 - 0.091 12.1 0.2 5.5 6.3 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family RNA_helicase PF00910.22 KKK19290.1 - 0.16 12.4 0.0 31 5.0 0.0 2.6 2 0 0 2 2 2 0 RNA helicase DLH PF01738.18 KKK19291.1 - 1.3e-17 64.1 0.1 6.8e-17 61.7 0.1 1.8 1 1 0 1 1 1 1 Dienelactone hydrolase family Rif1_N PF12231.8 KKK19292.1 - 6.1e-141 469.8 0.0 9.5e-141 469.1 0.0 1.3 1 0 0 1 1 1 1 Rap1-interacting factor 1 N terminal Ric8 PF10165.9 KKK19293.1 - 7.2e-114 381.3 0.0 8.8e-114 381.1 0.0 1.1 1 0 0 1 1 1 1 Guanine nucleotide exchange factor synembryn Pkinase PF00069.25 KKK19294.1 - 2.8e-40 138.4 0.0 8.1e-40 136.8 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK19294.1 - 7.7e-28 97.5 0.0 1.1e-27 97.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KKK19294.1 - 0.002 17.5 0.0 0.0043 16.4 0.0 1.5 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KKK19294.1 - 0.0056 16.6 2.6 0.25 11.3 0.1 3.0 2 1 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KKK19294.1 - 0.0058 16.0 0.0 0.027 13.8 0.0 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Sulfotransfer_4 PF17784.1 KKK19295.1 - 1.5e-40 139.3 0.0 7.5e-22 78.2 0.0 2.0 1 1 1 2 2 2 2 Sulfotransferase domain DAHP_synth_2 PF01474.16 KKK19297.1 - 3.3e-46 157.7 0.1 3.6e-46 157.6 0.1 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family CR6_interact PF10147.9 KKK19298.1 - 0.026 14.3 5.0 0.039 13.7 5.0 1.3 1 0 0 1 1 1 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 MFS_1 PF07690.16 KKK19299.1 - 2.1e-26 92.7 19.7 3.4e-26 92.0 19.7 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Cep57_CLD_2 PF14197.6 KKK19299.1 - 6.5e-21 74.2 9.5 6.5e-21 74.2 9.5 3.9 4 0 0 4 4 4 1 Centrosome localisation domain of PPC89 Cep57_MT_bd PF06657.13 KKK19299.1 - 4.7e-13 49.4 3.5 1.4e-07 31.9 0.1 5.0 4 1 1 5 5 5 2 Centrosome microtubule-binding domain of Cep57 Sugar_tr PF00083.24 KKK19299.1 - 6.6e-05 21.9 3.5 0.00017 20.6 3.5 1.6 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_4 PF06779.14 KKK19299.1 - 0.00067 19.1 1.0 0.0014 18.0 1.0 1.5 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB MFS_3 PF05977.13 KKK19299.1 - 0.0052 15.2 1.3 0.01 14.2 1.3 1.4 1 0 0 1 1 1 1 Transmembrane secretion effector CHASE9 PF17153.4 KKK19299.1 - 0.4 10.8 3.8 2.4 8.3 0.5 2.5 2 0 0 2 2 2 0 Periplasmic sensor domain, extracellular CAF1A PF12253.8 KKK19299.1 - 4.9 7.4 10.0 2.5 8.3 3.0 3.2 2 0 0 2 2 2 0 Chromatin assembly factor 1 subunit A DUF4810 PF16068.5 KKK19300.1 - 0.02 15.4 1.9 9.1 6.9 0.0 3.7 3 1 1 4 4 4 0 Domain of unknown function (DUF4810) TPR_14 PF13428.6 KKK19300.1 - 0.068 14.0 11.6 3.5 8.7 0.3 5.7 4 2 3 7 7 7 0 Tetratricopeptide repeat TPR_19 PF14559.6 KKK19300.1 - 0.1 13.1 0.0 3.2 8.3 0.0 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat Gla PF00594.20 KKK19300.1 - 9.5 6.5 9.7 1.6 9.0 0.1 3.7 5 0 0 5 5 5 0 Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain MAT1 PF06391.13 KKK19301.1 - 2.8e-41 141.6 12.4 3.6e-41 141.3 12.4 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4_5 PF17121.5 KKK19301.1 - 9.6e-33 111.8 9.0 1.5e-32 111.2 9.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KKK19301.1 - 0.00032 20.5 4.6 0.001 18.9 4.8 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KKK19301.1 - 0.00035 20.4 3.8 0.00072 19.4 3.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KKK19301.1 - 0.0052 17.1 6.9 0.0088 16.4 6.9 1.4 1 0 0 1 1 1 1 Ring finger domain Zn_ribbon_17 PF17120.5 KKK19301.1 - 0.0096 15.5 2.4 0.021 14.4 2.4 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_4 PF14570.6 KKK19301.1 - 0.011 15.5 4.9 0.21 11.4 1.9 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain DUF5338 PF17273.2 KKK19301.1 - 0.023 14.8 1.0 4.3 7.5 0.4 2.8 2 0 0 2 2 2 0 Family of unknown function (DUF5338) zf-RING_5 PF14634.6 KKK19301.1 - 0.036 14.0 8.4 0.46 10.5 9.2 2.2 1 1 1 2 2 2 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 KKK19301.1 - 0.21 11.6 6.0 0.43 10.6 6.0 1.5 1 0 0 1 1 1 0 RING-type zinc-finger Prok-RING_4 PF14447.6 KKK19301.1 - 1.5 8.8 9.2 30 4.6 9.9 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 DUF3797 PF12677.7 KKK19301.1 - 1.6 8.7 7.2 0.11 12.4 2.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3797) DUF3835 PF12927.7 KKK19302.1 - 2e-26 92.6 9.8 5.4e-24 84.9 0.2 3.9 3 1 1 4 4 4 2 Domain of unknown function (DUF3835) Prefoldin_3 PF13758.6 KKK19302.1 - 2.4e-17 62.8 0.8 5.4e-14 52.1 0.1 2.8 1 1 1 2 2 2 2 Prefoldin subunit CCDC-167 PF15188.6 KKK19302.1 - 0.86 10.0 5.8 12 6.3 3.6 3.0 2 1 0 2 2 2 0 Coiled-coil domain-containing protein 167 NGP1NT PF08153.12 KKK19303.1 - 2.1e-49 167.0 0.1 3.4e-49 166.3 0.1 1.3 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.23 KKK19303.1 - 2.3e-16 59.9 0.0 2.3e-13 50.2 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 KKK19303.1 - 0.00016 21.2 0.0 0.00049 19.6 0.0 1.8 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KKK19303.1 - 0.0015 18.5 0.0 0.0033 17.4 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase Dynamin_N PF00350.23 KKK19303.1 - 0.0015 18.6 0.1 0.27 11.3 0.0 3.2 2 1 1 3 3 3 1 Dynamin family Arf PF00025.21 KKK19303.1 - 0.0035 16.8 0.0 0.16 11.5 0.0 2.3 2 0 0 2 2 2 1 ADP-ribosylation factor family DUF2244 PF10003.9 KKK19305.1 - 0.075 12.7 7.5 0.47 10.1 0.1 2.4 2 1 0 2 2 2 0 Integral membrane protein (DUF2244) DUF4282 PF14110.6 KKK19305.1 - 0.42 11.4 12.8 1.4 9.7 7.1 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4282) DUF2070 PF09843.9 KKK19305.1 - 1.9 6.7 11.1 1 7.6 8.9 1.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2070) DEAD PF00270.29 KKK19306.1 - 2.6e-47 160.8 0.0 9.8e-47 159.0 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KKK19306.1 - 9.8e-30 103.2 0.0 2.1e-28 98.8 0.1 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KKK19306.1 - 0.0011 19.0 0.0 0.0025 17.9 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2986 PF11661.8 KKK19306.1 - 0.0044 17.5 2.6 0.016 15.8 2.6 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2986) DUF3334 PF11813.8 KKK19306.1 - 0.14 11.9 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3334) But2 PF09792.9 KKK19307.1 - 4.4e-59 199.0 2.0 4.4e-59 199.0 2.0 3.6 3 1 1 4 4 4 1 Ubiquitin 3 binding protein But2 C-terminal domain Toxin_10 PF05431.11 KKK19307.1 - 0.035 13.6 0.3 0.035 13.6 0.3 1.8 2 0 0 2 2 2 0 Insecticidal Crystal Toxin, P42 Anti-TRAP PF15777.5 KKK19307.1 - 1.2 9.2 4.8 4.2 7.4 0.0 4.0 5 0 0 5 5 5 0 Tryptophan RNA-binding attenuator protein inhibitory protein TFIIA PF03153.13 KKK19307.1 - 3.4 7.6 15.0 4.5 7.2 15.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Apt1 PF10351.9 KKK19307.1 - 7.9 5.2 10.4 12 4.6 10.4 1.4 1 0 0 1 1 1 0 Golgi-body localisation protein domain PAP2 PF01569.21 KKK19308.1 - 1.7e-28 99.1 0.1 3.3e-28 98.1 0.1 1.5 1 0 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.6 KKK19308.1 - 0.046 13.4 3.3 0.21 11.3 3.4 2.0 1 1 0 1 1 1 0 PAP2 superfamily AMMECR1 PF01871.17 KKK19310.1 - 1.7e-40 138.4 0.0 3.8e-40 137.2 0.0 1.5 2 0 0 2 2 2 1 AMMECR1 Pkinase PF00069.25 KKK19311.1 - 1.7e-72 244.0 0.0 2.2e-72 243.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK19311.1 - 9.1e-30 103.8 0.0 1.2e-29 103.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KKK19311.1 - 1.4e-07 31.1 0.0 2.4e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KKK19311.1 - 8.3e-05 21.5 0.0 0.00014 20.7 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KKK19311.1 - 0.00016 21.1 0.0 0.00029 20.2 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KKK19311.1 - 0.00053 20.0 0.1 0.00089 19.2 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family BRD4_CDT PF17105.5 KKK19311.1 - 0.21 11.2 1.1 0.46 10.1 1.1 1.5 1 0 0 1 1 1 0 C-terminal domain of bromodomain protein 4 Cnn_1N PF07989.11 KKK19312.1 - 1.1e-24 86.4 5.6 1.1e-24 86.4 5.6 14.7 5 3 10 15 15 15 2 Centrosomin N-terminal motif 1 PACT_coil_coil PF10495.9 KKK19312.1 - 1.3e-21 76.9 2.0 1.3e-21 76.9 2.0 4.3 4 0 0 4 4 4 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein Bacillus_HBL PF05791.11 KKK19312.1 - 5.9e-05 23.0 7.0 5.9e-05 23.0 7.0 7.1 3 2 4 8 8 8 1 Bacillus haemolytic enterotoxin (HBL) TMF_DNA_bd PF12329.8 KKK19312.1 - 0.0046 16.9 13.6 0.0046 16.9 13.6 14.1 8 4 4 14 14 14 2 TATA element modulatory factor 1 DNA binding Pox_A_type_inc PF04508.12 KKK19312.1 - 0.059 13.2 0.1 0.059 13.2 0.1 10.3 13 0 0 13 13 13 0 Viral A-type inclusion protein repeat SGT1 PF07093.11 KKK19313.1 - 6.5e-93 312.2 15.2 2.3e-84 283.9 0.0 2.0 1 1 1 2 2 2 2 SGT1 protein Prefoldin_2 PF01920.20 KKK19314.1 - 1.2e-17 63.8 15.1 1.2e-17 63.8 12.0 2.0 2 0 0 2 2 2 1 Prefoldin subunit ERp29 PF07749.12 KKK19314.1 - 0.062 14.2 3.0 0.13 13.2 3.0 1.6 1 1 0 1 1 1 0 Endoplasmic reticulum protein ERp29, C-terminal domain PHM7_cyt PF14703.6 KKK19314.1 - 0.23 11.7 5.7 0.83 9.9 5.7 1.9 1 1 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter DUF724 PF05266.14 KKK19314.1 - 0.32 10.8 9.7 1.5 8.6 2.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF724) DivIC PF04977.15 KKK19314.1 - 0.49 10.2 15.7 0.14 12.0 1.1 3.1 3 0 0 3 3 3 0 Septum formation initiator Spc7 PF08317.11 KKK19314.1 - 0.92 8.3 13.1 1.3 7.9 11.4 1.9 1 1 1 2 2 2 0 Spc7 kinetochore protein FlaC_arch PF05377.11 KKK19314.1 - 1.1 9.7 7.3 14 6.1 0.2 2.9 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) HrpB7 PF09486.10 KKK19314.1 - 1.5 9.2 9.7 0.72 10.2 2.5 2.5 3 0 0 3 3 3 0 Bacterial type III secretion protein (HrpB7) BRE1 PF08647.11 KKK19314.1 - 1.6 8.9 12.0 2 8.6 2.4 2.9 3 0 0 3 3 3 0 BRE1 E3 ubiquitin ligase Spc24 PF08286.11 KKK19314.1 - 1.7 9.0 13.8 2.2 8.6 1.7 2.8 2 1 1 3 3 3 0 Spc24 subunit of Ndc80 Prefoldin PF02996.17 KKK19314.1 - 2.1 8.3 11.6 6.1 6.8 8.9 2.7 2 1 0 2 2 2 0 Prefoldin subunit TolA_bind_tri PF16331.5 KKK19314.1 - 3.4 7.8 17.5 0.14 12.3 1.0 3.5 3 1 0 3 3 3 0 TolA binding protein trimerisation UPF0242 PF06785.11 KKK19314.1 - 3.8 7.6 14.3 3.4 7.7 12.4 1.9 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Csm1_N PF18504.1 KKK19314.1 - 9.5 6.7 13.6 3.7 7.9 0.9 3.2 3 1 0 3 3 3 0 Csm1 N-terminal domain Vps4_C PF09336.10 KKK19315.1 - 8.3e-30 102.6 0.1 3.1e-29 100.7 0.1 2.1 2 0 0 2 2 1 1 Vps4 C terminal oligomerisation domain AAA PF00004.29 KKK19315.1 - 2.8e-27 95.8 0.0 2.3e-26 92.8 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) MIT PF04212.18 KKK19315.1 - 2.9e-24 84.9 2.5 2.9e-24 84.9 2.5 1.9 2 0 0 2 2 1 1 MIT (microtubule interacting and transport) domain AAA_lid_3 PF17862.1 KKK19315.1 - 8.8e-07 28.6 0.1 3.8e-05 23.4 0.0 2.8 3 0 0 3 3 2 1 AAA+ lid domain AAA_16 PF13191.6 KKK19315.1 - 6e-06 26.7 0.0 0.00067 20.1 0.1 2.5 2 1 1 3 3 2 1 AAA ATPase domain IstB_IS21 PF01695.17 KKK19315.1 - 1.1e-05 25.3 0.0 3.4e-05 23.6 0.0 1.8 1 1 0 1 1 1 1 IstB-like ATP binding protein RuvB_N PF05496.12 KKK19315.1 - 1.1e-05 25.2 0.0 2.6e-05 24.0 0.0 1.6 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KKK19315.1 - 2.7e-05 24.2 0.0 0.00015 21.8 0.0 2.2 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) DUF815 PF05673.13 KKK19315.1 - 4.8e-05 22.6 0.0 0.00069 18.8 0.0 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF815) TIP49 PF06068.13 KKK19315.1 - 7.8e-05 22.0 0.0 0.00013 21.3 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_22 PF13401.6 KKK19315.1 - 9.6e-05 22.7 0.0 0.013 15.8 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.6 KKK19315.1 - 0.00021 21.5 0.0 0.00044 20.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KKK19315.1 - 0.00032 21.3 0.0 0.0011 19.5 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_14 PF13173.6 KKK19315.1 - 0.00083 19.4 0.0 0.0015 18.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 KKK19315.1 - 0.0012 19.3 0.0 0.0095 16.3 0.0 2.5 2 0 0 2 2 2 1 RNA helicase AAA_24 PF13479.6 KKK19315.1 - 0.0029 17.3 0.1 0.012 15.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_2 PF07724.14 KKK19315.1 - 0.0037 17.4 0.0 0.029 14.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) USP8_dimer PF08969.11 KKK19315.1 - 0.0044 17.2 2.6 0.01 16.0 2.6 1.7 1 0 0 1 1 1 1 USP8 dimerisation domain AAA_17 PF13207.6 KKK19315.1 - 0.0061 17.0 0.0 0.02 15.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 KKK19315.1 - 0.026 14.5 0.4 0.61 9.9 0.0 2.6 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea AAA_7 PF12775.7 KKK19315.1 - 0.033 13.7 0.0 0.1 12.1 0.0 1.8 1 1 0 1 1 1 0 P-loop containing dynein motor region Mg_chelatase PF01078.21 KKK19315.1 - 0.033 13.6 0.1 0.092 12.1 0.1 1.7 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI Bac_DnaA PF00308.18 KKK19315.1 - 0.051 13.4 0.0 0.23 11.3 0.0 2.0 2 0 0 2 2 2 0 Bacterial dnaA protein AAA_25 PF13481.6 KKK19315.1 - 0.054 13.1 0.2 1.4 8.4 0.1 2.7 1 1 1 3 3 3 0 AAA domain CPT PF07931.12 KKK19315.1 - 0.057 13.3 0.0 0.28 11.0 0.0 1.9 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein NACHT PF05729.12 KKK19315.1 - 0.075 12.9 0.0 0.57 10.1 0.0 2.1 1 1 1 2 2 2 0 NACHT domain Cytidylate_kin PF02224.18 KKK19315.1 - 0.097 12.4 0.5 0.3 10.8 0.0 2.0 2 0 0 2 2 2 0 Cytidylate kinase Parvo_NS1 PF01057.17 KKK19315.1 - 0.11 11.6 0.0 0.24 10.4 0.0 1.5 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 ABC_tran PF00005.27 KKK19315.1 - 0.11 13.0 0.0 0.54 10.8 0.0 2.3 2 1 1 3 3 2 0 ABC transporter Guanylate_kin PF00625.21 KKK19315.1 - 0.14 11.9 0.0 0.37 10.5 0.0 1.7 1 0 0 1 1 1 0 Guanylate kinase Zeta_toxin PF06414.12 KKK19315.1 - 0.14 11.4 0.1 0.81 8.9 0.1 2.3 1 1 1 2 2 2 0 Zeta toxin Med9 PF07544.13 KKK19316.1 - 3.1e-16 59.2 0.0 4e-16 58.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 Med21 PF11221.8 KKK19316.1 - 0.0017 18.6 0.1 0.0019 18.5 0.1 1.2 1 0 0 1 1 1 1 Subunit 21 of Mediator complex DUF5082 PF16888.5 KKK19316.1 - 0.011 16.0 0.7 0.038 14.3 0.1 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) GP41 PF00517.17 KKK19316.1 - 0.035 14.0 0.1 0.045 13.7 0.1 1.1 1 0 0 1 1 1 0 Retroviral envelope protein XhlA PF10779.9 KKK19316.1 - 0.056 13.7 0.5 0.13 12.5 0.4 1.7 1 1 1 2 2 2 0 Haemolysin XhlA DUF2730 PF10805.8 KKK19316.1 - 0.063 13.4 0.0 0.084 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) DivIC PF04977.15 KKK19316.1 - 0.075 12.8 0.1 0.36 10.6 0.0 2.0 1 1 1 2 2 2 0 Septum formation initiator DUF2764 PF10962.8 KKK19316.1 - 0.19 11.2 0.0 0.25 10.8 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2764) iPGM_N PF06415.13 KKK19317.1 - 5.1e-77 258.2 0.0 7e-77 257.7 0.0 1.2 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Metalloenzyme PF01676.18 KKK19317.1 - 6.9e-70 235.2 0.0 8e-70 235.0 0.0 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily Phosphodiest PF01663.22 KKK19317.1 - 8.8e-05 22.2 0.0 0.00015 21.5 0.0 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 KKK19317.1 - 0.0019 17.7 0.0 0.01 15.2 0.0 2.3 2 1 0 2 2 2 1 Sulfatase Alk_phosphatase PF00245.20 KKK19317.1 - 0.072 12.0 0.1 0.28 10.1 0.0 1.8 2 0 0 2 2 2 0 Alkaline phosphatase AP_endonuc_2 PF01261.24 KKK19317.1 - 0.12 11.9 0.0 0.26 10.7 0.0 1.6 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel DUF2235 PF09994.9 KKK19317.1 - 0.14 11.5 0.0 10 5.4 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) 4HBT_3 PF13622.6 KKK19318.1 - 1.7e-36 126.7 0.1 2e-36 126.5 0.1 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily zf-C2H2 PF00096.26 KKK19320.1 - 9.2e-07 29.0 9.7 0.00049 20.4 0.4 3.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 KKK19320.1 - 1.3e-05 25.3 2.2 0.11 12.8 0.0 3.0 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding Fungal_trans PF04082.18 KKK19320.1 - 1.5e-05 24.2 0.2 6.2e-05 22.2 0.1 1.9 1 1 1 2 2 2 1 Fungal specific transcription factor domain Atg14 PF10186.9 KKK19320.1 - 0.0015 17.7 0.2 0.19 10.8 0.1 2.2 2 0 0 2 2 2 2 Vacuolar sorting 38 and autophagy-related subunit 14 zf-H2C2_2 PF13465.6 KKK19320.1 - 0.0043 17.4 5.3 0.0043 17.4 5.3 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_6 PF13912.6 KKK19320.1 - 0.0051 16.8 9.2 0.046 13.7 0.1 3.5 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_4 PF13894.6 KKK19320.1 - 0.0053 17.5 0.4 0.0053 17.5 0.4 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger LIM PF00412.22 KKK19320.1 - 0.97 9.7 4.3 3.9 7.8 4.3 2.1 1 0 0 1 1 1 0 LIM domain zf-C2H2_11 PF16622.5 KKK19320.1 - 1.3 8.8 4.7 7.9 6.3 0.0 3.0 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-met PF12874.7 KKK19320.1 - 2 8.9 4.8 12 6.4 0.1 3.3 4 0 0 4 4 4 0 Zinc-finger of C2H2 type MFS_1 PF07690.16 KKK19321.1 - 1.9e-40 138.9 14.8 3.1e-40 138.2 14.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KKK19321.1 - 9.3e-12 44.5 21.2 1.4e-10 40.6 5.2 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.13 KKK19321.1 - 3.9e-08 32.2 4.2 8.4e-07 27.8 1.2 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) DUF2207 PF09972.9 KKK19321.1 - 1.3 7.7 4.1 8.5 5.0 0.4 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) AA_permease PF00324.21 KKK19322.1 - 2.4e-99 333.1 37.5 3e-99 332.8 37.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KKK19322.1 - 2.6e-23 82.5 39.6 3.6e-23 82.1 39.6 1.1 1 0 0 1 1 1 1 Amino acid permease MgtE PF01769.16 KKK19322.1 - 0.036 14.4 1.6 0.036 14.4 1.6 4.3 3 1 0 3 3 3 0 Divalent cation transporter Raffinose_syn PF05691.12 KKK19323.1 - 2.4e-50 171.1 0.3 9.5e-48 162.6 0.3 2.5 2 1 0 2 2 2 1 Raffinose synthase or seed imbibition protein Sip1 Alpha-amylase PF00128.24 KKK19324.1 - 7.5e-18 65.2 0.2 3.7e-17 62.9 0.1 2.1 2 1 0 2 2 2 1 Alpha amylase, catalytic domain Glyco_transf_5 PF08323.11 KKK19324.1 - 1e-14 54.9 0.1 1.8e-14 54.0 0.1 1.3 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 KKK19324.1 - 5e-05 22.9 0.0 9.7e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KKK19324.1 - 0.018 15.0 0.0 0.046 13.7 0.0 1.6 1 0 0 1 1 1 0 Glycosyltransferase Family 4 ADH_zinc_N PF00107.26 KKK19325.1 - 9.8e-25 87.0 0.2 1.6e-24 86.3 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KKK19325.1 - 2.4e-16 61.0 0.0 5.3e-16 59.9 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KKK19325.1 - 2.6e-11 43.3 0.0 1e-10 41.5 0.0 2.0 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.18 KKK19325.1 - 0.0014 18.9 0.0 0.0024 18.1 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain ADH_N_2 PF16884.5 KKK19325.1 - 0.0048 16.8 0.0 0.0088 15.9 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase AlaDh_PNT_C PF01262.21 KKK19325.1 - 0.0063 15.8 0.0 0.012 14.9 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 KKK19325.1 - 0.052 12.9 0.0 0.078 12.3 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ELFV_dehydrog PF00208.21 KKK19325.1 - 0.064 13.0 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Alpha-amylase PF00128.24 KKK19326.1 - 9.2e-18 64.9 0.8 2.1e-16 60.4 0.9 2.2 1 1 0 2 2 2 1 Alpha amylase, catalytic domain Glyco_hydro_70 PF02324.16 KKK19326.1 - 2.8e-06 25.9 0.0 0.01 14.1 0.0 3.0 3 0 0 3 3 3 3 Glycosyl hydrolase family 70 DUF1939 PF09154.10 KKK19326.1 - 0.095 12.9 0.0 0.92 9.7 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1939) DUF1966 PF09260.11 KKK19327.1 - 5.4e-30 103.5 0.0 1.2e-29 102.4 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) Alpha-amylase PF00128.24 KKK19327.1 - 1e-27 97.6 0.1 1.4e-27 97.2 0.1 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DNMT1-RFD PF12047.8 KKK19328.1 - 0.0058 16.7 0.0 0.016 15.3 0.0 1.7 1 0 0 1 1 1 1 Cytosine specific DNA methyltransferase replication foci domain E3_UbLigase_EDD PF11547.8 KKK19328.1 - 0.039 13.6 0.6 1.5 8.6 0.9 2.9 3 0 0 3 3 3 0 E3 ubiquitin ligase EDD TruB_N PF01509.18 KKK19329.1 - 7.1e-47 159.5 0.0 4e-46 157.1 0.0 2.1 3 0 0 3 3 3 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 KKK19329.1 - 1e-06 28.7 0.0 2.1e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain Coilin_N PF15862.5 KKK19329.1 - 1.5 8.7 4.8 4.5 7.1 4.8 1.8 1 0 0 1 1 1 0 Coilin N-terminus Ndc1_Nup PF09531.10 KKK19329.1 - 1.5 7.4 7.4 2 7.0 7.4 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Ebp2 PF05890.12 KKK19330.1 - 4.2e-98 328.2 11.1 4.2e-98 328.2 11.1 2.1 1 1 0 2 2 2 1 Eukaryotic rRNA processing protein EBP2 Nop14 PF04147.12 KKK19330.1 - 3.4 5.8 41.2 0.014 13.7 27.1 2.1 2 0 0 2 2 2 0 Nop14-like family DUF1279 PF06916.13 KKK19339.1 - 6.6e-11 42.6 0.0 1.1e-10 41.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) JmjC PF02373.22 KKK19340.1 - 4.4e-37 127.0 0.8 4.4e-37 127.0 0.8 2.6 4 0 0 4 4 4 1 JmjC domain, hydroxylase zf-HC5HC2H PF13771.6 KKK19340.1 - 3e-18 65.8 4.4 7e-18 64.7 4.4 1.7 1 0 0 1 1 1 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 KKK19340.1 - 9.7e-18 64.3 4.9 1.9e-17 63.4 4.9 1.4 1 0 0 1 1 1 1 PHD-zinc-finger like domain JmjN PF02375.17 KKK19340.1 - 4.1e-15 55.5 0.2 1.1e-14 54.1 0.2 1.8 1 0 0 1 1 1 1 jmjN domain Macoilin PF09726.9 KKK19340.1 - 0.11 11.1 3.3 0.17 10.4 3.3 1.2 1 0 0 1 1 1 0 Macoilin family EPL1 PF10513.9 KKK19340.1 - 0.55 10.6 12.4 0.55 10.6 8.1 2.5 2 0 0 2 2 2 0 Enhancer of polycomb-like Folliculin PF11704.8 KKK19340.1 - 3.9 7.3 8.3 0.65 9.8 3.6 2.0 2 0 0 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport TPR_17 PF13431.6 KKK19343.1 - 0.011 16.0 0.0 0.45 11.0 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 KKK19343.1 - 0.068 12.9 0.1 0.86 9.3 0.0 2.7 3 0 0 3 3 3 0 TPR repeat Glyoxalase_5 PF14696.6 KKK19344.1 - 2e-05 24.8 0.0 0.00084 19.5 0.0 2.1 1 1 0 1 1 1 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Glyoxalase_4 PF13669.6 KKK19344.1 - 3.1e-05 24.2 0.0 6.2e-05 23.2 0.0 1.5 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase PF00903.25 KKK19344.1 - 0.0028 17.8 0.1 0.0055 16.9 0.1 1.5 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 KKK19344.1 - 0.013 15.6 0.1 0.086 12.9 0.1 2.0 1 1 0 1 1 1 0 Glyoxalase-like domain DASH_Dad2 PF08654.10 KKK19344.1 - 0.13 12.7 0.0 0.18 12.3 0.0 1.2 1 0 0 1 1 1 0 DASH complex subunit Dad2 p450 PF00067.22 KKK19345.1 - 2.5e-60 204.6 0.0 3.4e-60 204.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 SGL PF08450.12 KKK19345.1 - 2e-30 106.2 0.1 3.7e-30 105.3 0.1 1.4 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Arylesterase PF01731.20 KKK19345.1 - 9.8e-05 22.5 0.0 0.0003 20.9 0.0 1.8 1 0 0 1 1 1 1 Arylesterase NHL PF01436.21 KKK19345.1 - 0.0052 16.8 0.7 0.17 12.0 0.0 2.7 2 0 0 2 2 2 1 NHL repeat Str_synth PF03088.16 KKK19345.1 - 0.11 12.6 0.0 0.52 10.5 0.0 2.1 2 1 0 2 2 2 0 Strictosidine synthase Arginosuc_synth PF00764.19 KKK19346.1 - 9.4e-158 525.5 0.0 1.1e-157 525.3 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.13 KKK19346.1 - 2.4e-05 23.9 0.0 3.9e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 KKK19346.1 - 0.0056 15.5 0.0 0.0086 14.9 0.0 1.3 1 0 0 1 1 1 1 tRNA methyl transferase Asn_synthase PF00733.21 KKK19346.1 - 0.1 12.2 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 Asparagine synthase Zn_clus PF00172.18 KKK19347.1 - 6.2e-06 26.2 7.1 1.4e-05 25.1 7.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.12 KKK19347.1 - 2.3 8.8 5.3 22 5.6 0.7 2.4 2 0 0 2 2 2 0 Dickkopf N-terminal cysteine-rich region Tim17 PF02466.19 KKK19348.1 - 4.5e-32 110.7 8.7 5.5e-32 110.4 8.7 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family VMA21 PF09446.10 KKK19348.1 - 0.18 11.9 0.8 0.41 10.8 0.4 1.7 2 0 0 2 2 2 0 VMA21-like domain GST_N_2 PF13409.6 KKK19349.1 - 5.2e-09 36.3 0.0 1.3e-08 35.0 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KKK19349.1 - 1.8e-08 34.6 0.0 3.1e-07 30.6 0.0 2.2 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KKK19349.1 - 1.2e-06 28.9 0.0 2.2e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KKK19349.1 - 1.6e-06 28.3 0.0 2.5e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KKK19349.1 - 3.8e-06 27.0 0.0 7e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KKK19349.1 - 0.0021 18.0 0.1 0.004 17.1 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain F-box-like PF12937.7 KKK19350.1 - 2.5e-05 24.1 0.2 5.8e-05 22.9 0.2 1.7 1 0 0 1 1 1 1 F-box-like HgmA PF04209.13 KKK19351.1 - 3.1e-210 698.2 0.1 3.6e-210 698.1 0.1 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase FAA_hydrolase PF01557.18 KKK19352.1 - 5.1e-53 180.0 0.0 6.8e-53 179.6 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.11 KKK19352.1 - 6.8e-31 106.6 0.0 1.2e-30 105.8 0.0 1.4 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal FAD_binding_3 PF01494.19 KKK19353.1 - 1.7e-14 53.8 0.0 2.8e-14 53.1 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KKK19353.1 - 0.034 13.4 0.1 0.15 11.3 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Nucleoporin2 PF04096.14 KKK19354.1 - 6.1e-49 166.0 0.0 1.2e-48 165.0 0.0 1.5 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.6 KKK19354.1 - 6.6e-11 42.9 93.3 6.9e-07 30.0 41.6 10.3 4 2 6 10 10 10 4 Nucleoporin FG repeat region Tet_res_leader PF08050.12 KKK19354.1 - 0.23 11.3 0.3 0.46 10.4 0.3 1.4 1 0 0 1 1 1 0 Tetracycline resistance leader peptide Prefoldin_2 PF01920.20 KKK19355.1 - 4.9e-23 81.1 3.4 5.4e-23 81.0 3.4 1.0 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin PF02996.17 KKK19355.1 - 0.0065 16.4 5.3 0.0098 15.8 0.4 2.1 1 1 1 2 2 2 1 Prefoldin subunit ALIX_LYPXL_bnd PF13949.6 KKK19355.1 - 0.016 14.5 1.2 0.019 14.3 1.2 1.1 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV GPS2_interact PF15784.5 KKK19355.1 - 0.032 14.7 3.3 0.047 14.1 0.1 2.1 2 1 0 2 2 2 0 G-protein pathway suppressor 2-interacting domain DUF1640 PF07798.11 KKK19355.1 - 0.049 13.7 0.7 0.073 13.1 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) CdvA PF18822.1 KKK19355.1 - 0.054 13.3 3.5 2.9 7.7 0.9 2.2 2 0 0 2 2 2 0 CdvA-like coiled-coil domain Oxidored_nitro PF00148.19 KKK19355.1 - 0.064 12.0 0.0 0.089 11.5 0.0 1.2 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase TBCA PF02970.16 KKK19355.1 - 0.11 12.8 5.2 0.44 10.9 5.2 1.8 1 1 0 1 1 1 0 Tubulin binding cofactor A ATG16 PF08614.11 KKK19355.1 - 0.13 12.5 0.4 0.13 12.5 0.4 2.0 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) DUF1664 PF07889.12 KKK19355.1 - 0.13 12.3 0.5 0.98 9.5 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) PEP-utilisers_N PF05524.13 KKK19355.1 - 0.15 12.2 4.6 0.15 12.2 0.1 2.0 1 1 1 2 2 2 0 PEP-utilising enzyme, N-terminal DivIC PF04977.15 KKK19355.1 - 0.2 11.5 7.3 2.2 8.1 1.5 2.2 2 0 0 2 2 2 0 Septum formation initiator DASH_Dam1 PF08653.10 KKK19355.1 - 0.27 11.0 0.7 0.97 9.3 0.1 2.1 2 1 0 2 2 2 0 DASH complex subunit Dam1 bZIP_1 PF00170.21 KKK19355.1 - 5.1 7.3 7.2 0.76 9.9 0.3 2.1 2 0 0 2 2 2 0 bZIP transcription factor N2227 PF07942.12 KKK19356.1 - 1e-90 303.6 0.0 1.3e-90 303.3 0.0 1.1 1 0 0 1 1 1 1 N2227-like protein Methyltransf_23 PF13489.6 KKK19356.1 - 0.047 13.5 0.0 0.087 12.7 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 KKK19356.1 - 0.051 14.3 0.0 0.24 12.2 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 KKK19356.1 - 0.068 13.8 0.0 0.21 12.2 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain PAC4 PF16093.5 KKK19357.1 - 4e-26 91.0 0.6 5.7e-26 90.5 0.6 1.2 1 0 0 1 1 1 1 Proteasome assembly chaperone 4 Fungal_trans PF04082.18 KKK19358.1 - 1.7e-21 76.5 0.1 3.3e-21 75.5 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK19358.1 - 1.2e-05 25.3 14.2 3.2e-05 24.0 14.2 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Myosin_head PF00063.21 KKK19370.1 - 2.1e-264 878.9 2.8 3e-264 878.4 2.8 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) NAP PF00956.18 KKK19370.1 - 3.8e-96 321.4 9.2 3.8e-96 321.4 9.2 2.6 2 1 0 2 2 1 1 Nucleosome assembly protein (NAP) DIL PF01843.19 KKK19370.1 - 4.2e-26 91.2 2.6 4.2e-26 91.2 2.6 2.6 2 1 1 3 3 3 1 DIL domain IQ PF00612.27 KKK19370.1 - 1.7e-12 45.9 33.9 4.4e-05 22.9 0.2 6.8 6 0 0 6 6 6 4 IQ calmodulin-binding motif CENP-B_dimeris PF09026.10 KKK19370.1 - 2.8e-06 27.7 24.4 9.6e-05 22.7 10.0 3.1 2 0 0 2 2 2 2 Centromere protein B dimerisation domain KASH_CCD PF14662.6 KKK19370.1 - 0.00041 20.2 11.6 0.00041 20.2 11.6 2.9 1 1 1 2 2 2 1 Coiled-coil region of CCDC155 or KASH AAA_22 PF13401.6 KKK19370.1 - 0.0013 19.0 2.8 0.0091 16.3 0.0 3.0 2 0 0 2 2 2 1 AAA domain GAS PF13851.6 KKK19370.1 - 0.024 14.0 41.1 0.0059 16.0 16.4 3.4 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding AAA_16 PF13191.6 KKK19370.1 - 0.043 14.2 0.0 0.043 14.2 0.0 2.8 3 0 0 3 3 2 0 AAA ATPase domain DUF3450 PF11932.8 KKK19370.1 - 0.05 12.9 32.0 0.042 13.2 15.4 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) RNA_helicase PF00910.22 KKK19370.1 - 0.16 12.4 0.0 0.98 9.8 0.0 2.4 2 0 0 2 2 2 0 RNA helicase Spc7 PF08317.11 KKK19370.1 - 0.16 10.8 29.8 0.91 8.3 29.8 2.2 1 1 0 1 1 1 0 Spc7 kinetochore protein Atg14 PF10186.9 KKK19370.1 - 0.18 10.8 31.0 0.23 10.5 12.0 2.7 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 ATG16 PF08614.11 KKK19370.1 - 0.19 12.0 37.5 4.1 7.6 21.3 3.2 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Imm68 PF15583.6 KKK19370.1 - 0.36 11.0 3.9 1.1 9.4 3.9 1.9 1 0 0 1 1 1 0 Immunity protein 68 Myosin_N PF02736.19 KKK19370.1 - 0.65 9.9 3.5 0.38 10.6 0.7 2.2 2 0 0 2 2 2 0 Myosin N-terminal SH3-like domain FlaC_arch PF05377.11 KKK19370.1 - 2.2 8.7 12.6 0.58 10.6 0.7 4.3 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) HIP1_clath_bdg PF16515.5 KKK19370.1 - 4.8 7.9 26.4 21 5.8 10.3 4.0 3 0 0 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 FUSC PF04632.12 KKK19370.1 - 7.7 4.9 9.8 14 4.1 9.8 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family Ham1p_like PF01725.16 KKK19371.1 - 2.1e-60 203.8 0.0 2.4e-60 203.7 0.0 1.0 1 0 0 1 1 1 1 Ham1 family AAA_18 PF13238.6 KKK19372.1 - 1.6e-23 83.6 0.1 3e-23 82.8 0.0 1.4 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 KKK19372.1 - 1.1e-06 29.1 0.0 3.4e-06 27.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 KKK19372.1 - 0.00017 22.0 0.0 0.00039 20.8 0.0 1.7 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 KKK19372.1 - 0.0021 18.2 0.0 0.0055 16.9 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KKK19372.1 - 0.004 17.4 0.1 0.0069 16.7 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 KKK19372.1 - 0.0049 17.1 0.0 0.0076 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain ADK PF00406.22 KKK19372.1 - 0.0057 16.8 0.0 0.011 15.8 0.0 1.6 2 0 0 2 2 2 1 Adenylate kinase Hydin_ADK PF17213.3 KKK19372.1 - 0.0062 16.8 0.0 0.0091 16.3 0.0 1.2 1 0 0 1 1 1 1 Hydin Adenylate kinase-like domain Death PF00531.22 KKK19372.1 - 0.014 15.6 0.1 0.051 13.7 0.1 1.9 2 0 0 2 2 2 0 Death domain AAA_16 PF13191.6 KKK19372.1 - 0.02 15.3 0.1 0.029 14.7 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain NTPase_1 PF03266.15 KKK19372.1 - 0.032 14.1 0.0 0.059 13.3 0.0 1.5 1 0 0 1 1 1 0 NTPase Viral_helicase1 PF01443.18 KKK19372.1 - 0.034 13.9 0.0 0.047 13.4 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Cytidylate_kin2 PF13189.6 KKK19372.1 - 0.036 14.2 0.0 0.042 14.0 0.0 1.4 1 1 0 1 1 1 0 Cytidylate kinase-like family AAA_14 PF13173.6 KKK19372.1 - 0.038 14.0 0.0 0.062 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 KKK19372.1 - 0.075 13.4 0.0 0.079 13.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.10 KKK19372.1 - 0.08 12.4 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 RNA_helicase PF00910.22 KKK19372.1 - 0.085 13.3 0.0 0.15 12.5 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AA_kinase PF00696.28 KKK19373.1 - 1.2e-42 146.2 0.3 1.8e-42 145.6 0.3 1.3 1 0 0 1 1 1 1 Amino acid kinase family ACT_7 PF13840.6 KKK19373.1 - 8.3e-12 44.7 0.8 1.3e-09 37.7 0.1 2.7 2 0 0 2 2 2 2 ACT domain ACT PF01842.25 KKK19373.1 - 4.2e-11 42.4 0.3 2.2e-08 33.7 0.1 2.9 2 1 0 2 2 2 2 ACT domain Peptidase_C78 PF07910.13 KKK19374.1 - 1.6e-70 236.9 0.0 2e-70 236.6 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C78 Hist_deacetyl PF00850.19 KKK19374.1 - 0.0028 17.2 0.0 0.0039 16.7 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain SseB_C PF14581.6 KKK19374.1 - 0.074 13.2 0.0 0.21 11.7 0.0 1.7 1 0 0 1 1 1 0 SseB protein C-terminal domain G10 PF01125.17 KKK19375.1 - 1.3e-68 229.4 5.1 1.4e-68 229.2 5.1 1.0 1 0 0 1 1 1 1 G10 protein Forkhead PF00250.18 KKK19376.1 - 8.2e-36 122.1 0.1 1.5e-35 121.3 0.1 1.4 1 0 0 1 1 1 1 Forkhead domain UCR_14kD PF02271.16 KKK19378.1 - 7.9e-45 150.9 0.1 9.1e-45 150.7 0.1 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit Mito_carr PF00153.27 KKK19379.1 - 1.9e-66 220.0 2.0 3.8e-23 81.2 0.1 3.4 2 2 1 3 3 3 3 Mitochondrial carrier protein Ecm33 PF12454.8 KKK19380.1 - 1.1e-13 51.0 0.9 1.1e-13 51.0 0.9 2.0 2 0 0 2 2 2 1 GPI-anchored cell wall organization protein LRR_5 PF13306.6 KKK19380.1 - 3e-07 30.4 0.3 0.011 15.7 0.2 2.6 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) FAM199X PF15814.5 KKK19380.1 - 0.0034 16.5 0.7 0.007 15.5 0.7 1.4 1 0 0 1 1 1 1 Protein family FAM199X IMUP PF15761.5 KKK19380.1 - 0.47 11.2 4.2 0.84 10.3 4.2 1.3 1 0 0 1 1 1 0 Immortalisation up-regulated protein Peptidase_A21 PF03566.13 KKK19380.1 - 3.6 5.7 10.9 0.25 9.5 4.1 1.9 2 0 0 2 2 2 0 Peptidase family A21 HhH-GPD PF00730.25 KKK19381.1 - 9e-11 42.2 0.0 1.8e-10 41.2 0.0 1.5 1 1 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein Anp1 PF03452.14 KKK19382.1 - 1.9e-106 355.3 0.0 2.4e-106 355.0 0.0 1.1 1 0 0 1 1 1 1 Anp1 Herpes_UL6 PF01763.16 KKK19383.1 - 0.0011 17.6 1.6 0.0015 17.1 1.6 1.1 1 0 0 1 1 1 1 Herpesvirus UL6 like Rootletin PF15035.6 KKK19383.1 - 0.0017 18.4 5.5 0.0025 17.9 5.5 1.3 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion Med4 PF10018.9 KKK19383.1 - 0.0066 16.1 4.0 0.017 14.8 4.0 1.7 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 Tropomyosin_1 PF12718.7 KKK19383.1 - 0.02 15.0 5.9 0.02 15.0 5.9 1.6 2 0 0 2 2 2 0 Tropomyosin like DUF3450 PF11932.8 KKK19383.1 - 0.032 13.5 7.8 0.047 13.0 7.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF3452 PF11934.8 KKK19383.1 - 0.068 12.7 0.2 2 8.0 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3452) YabA PF06156.13 KKK19383.1 - 0.077 13.6 6.6 0.096 13.3 3.8 2.1 2 0 0 2 2 2 0 Initiation control protein YabA bZIP_1 PF00170.21 KKK19383.1 - 0.085 13.0 7.7 0.18 11.9 6.0 2.3 1 1 1 2 2 2 0 bZIP transcription factor DUF3886 PF13025.6 KKK19383.1 - 0.17 12.1 8.8 0.38 11.0 8.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3886) SlyX PF04102.12 KKK19383.1 - 0.2 12.3 8.6 0.5 11.0 8.6 1.8 1 0 0 1 1 1 0 SlyX DUF5595 PF18077.1 KKK19383.1 - 0.65 10.1 2.9 1.3 9.1 2.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5595) 7tm_7 PF08395.12 KKK19383.1 - 0.71 9.0 2.6 1.1 8.3 2.6 1.2 1 0 0 1 1 1 0 7tm Chemosensory receptor CAGE1 PF15066.6 KKK19383.1 - 0.72 8.4 12.1 1 8.0 12.1 1.1 1 0 0 1 1 1 0 Cancer-associated gene protein 1 family DivIC PF04977.15 KKK19383.1 - 0.94 9.3 11.0 1.9 8.3 10.5 1.7 1 1 0 1 1 1 0 Septum formation initiator Sas6_CC PF18594.1 KKK19383.1 - 1.1 9.1 3.9 7 6.5 3.9 2.3 1 1 0 1 1 1 0 Sas6/XLF/XRCC4 coiled-coil domain TERB2 PF15101.6 KKK19383.1 - 1.4 9.0 4.9 2.7 8.0 4.9 1.4 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF5320 PF17253.2 KKK19383.1 - 2.2 9.4 4.3 4.9 8.3 4.3 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5320) KfrA_N PF11740.8 KKK19383.1 - 2.5 8.8 7.9 5.5 7.7 7.9 1.5 1 0 0 1 1 1 0 Plasmid replication region DNA-binding N-term Filament_head PF04732.14 KKK19391.1 - 3.6 8.5 8.0 12 6.9 0.5 2.5 2 0 0 2 2 2 0 Intermediate filament head (DNA binding) region Nop14 PF04147.12 KKK19391.1 - 7.2 4.7 19.1 0.48 8.6 5.9 2.0 2 0 0 2 2 2 0 Nop14-like family Cofilin_ADF PF00241.20 KKK19405.1 - 8.8e-29 99.8 0.0 1e-17 64.1 0.0 2.1 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein DNA_topoisoIV PF00521.20 KKK19406.1 - 9.4e-98 327.9 6.5 1.4e-80 271.3 1.6 2.5 2 0 0 2 2 2 2 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 KKK19406.1 - 3.6e-53 179.2 4.6 1.3e-51 174.2 3.0 3.0 2 0 0 2 2 2 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 KKK19406.1 - 1.5e-25 89.7 0.3 4.4e-25 88.1 0.3 1.8 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 KKK19406.1 - 3.9e-16 59.5 0.1 1.1e-15 58.2 0.1 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 KKK19406.1 - 1.5e-07 31.5 0.0 7.3e-07 29.4 0.0 2.2 1 0 0 1 1 1 1 Toprim domain Nsp1_C PF05064.13 KKK19406.1 - 0.015 15.1 0.1 0.051 13.4 0.1 1.9 1 0 0 1 1 1 0 Nsp1-like C-terminal region AT_hook PF02178.19 KKK19406.1 - 0.11 12.4 2.2 0.51 10.4 2.2 2.3 1 0 0 1 1 1 0 AT hook motif RabGAP-TBC PF00566.18 KKK19407.1 - 3.3e-48 164.2 0.6 2.9e-47 161.1 0.0 2.5 3 0 0 3 3 3 1 Rab-GTPase-TBC domain Reticulon PF02453.17 KKK19408.1 - 4.1e-27 95.1 5.0 5.3e-27 94.7 5.0 1.1 1 0 0 1 1 1 1 Reticulon Cytochrome-c551 PF10643.9 KKK19408.1 - 0.083 12.5 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Photosystem P840 reaction-centre cytochrome c-551 ADP_ribosyl_GH PF03747.14 KKK19410.1 - 7.2e-57 193.3 0.2 8.2e-57 193.1 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase Tyrosinase PF00264.20 KKK19411.1 - 4.8e-40 138.2 0.7 7.1e-34 118.0 0.0 2.3 2 0 0 2 2 2 2 Common central domain of tyrosinase Patatin PF01734.22 KKK19413.1 - 2.1e-12 47.7 0.0 5.7e-12 46.2 0.0 1.8 1 1 0 1 1 1 1 Patatin-like phospholipase Fungal_trans PF04082.18 KKK19414.1 - 7e-11 41.7 0.8 1.2e-10 40.9 0.8 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK19414.1 - 3.6e-09 36.6 9.1 6.8e-09 35.7 9.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain INCENP_ARK-bind PF03941.15 KKK19415.1 - 9.8e-15 54.2 0.7 9.8e-15 54.2 0.7 2.9 2 0 0 2 2 2 1 Inner centromere protein, ARK binding region Pkinase PF00069.25 KKK19416.1 - 0.033 13.5 0.0 0.063 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein kinase domain APH PF01636.23 KKK19416.1 - 0.21 11.5 1.2 0.32 10.9 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family Abhydrolase_1 PF00561.20 KKK19418.1 - 2e-11 44.1 0.2 8e-10 38.8 0.1 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KKK19418.1 - 7.5e-11 43.0 4.3 1e-10 42.6 4.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KKK19418.1 - 7.5e-06 25.4 0.0 1.4e-05 24.5 0.0 1.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 CitMHS PF03600.16 KKK19419.1 - 3.2e-09 36.4 14.6 1.1e-08 34.7 14.6 2.0 1 1 0 1 1 1 1 Citrate transporter ArsB PF02040.15 KKK19419.1 - 9.4e-09 35.1 16.5 2.9e-05 23.6 6.1 2.3 2 0 0 2 2 2 2 Arsenical pump membrane protein Cutinase PF01083.22 KKK19420.1 - 1.8e-43 148.5 5.7 2.2e-43 148.3 5.7 1.0 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 KKK19420.1 - 0.00039 20.0 1.4 0.00073 19.1 0.2 1.8 1 1 1 2 2 2 1 PE-PPE domain Abhydrolase_6 PF12697.7 KKK19420.1 - 0.011 16.3 0.5 0.013 16.1 0.5 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase family NACHT_N PF17100.5 KKK19423.1 - 3e-32 112.3 1.0 9.8e-32 110.6 0.0 1.9 1 1 1 2 2 2 1 N-terminal domain of NWD NACHT-NTPase NACHT PF05729.12 KKK19423.1 - 1.2e-06 28.5 0.5 6.3e-06 26.2 0.0 2.2 2 1 1 3 3 3 1 NACHT domain Rab5-bind PF09311.11 KKK19423.1 - 4.1e-05 23.1 4.0 5.9e-05 22.6 4.0 1.1 1 0 0 1 1 1 1 Rabaptin-like protein AAA_32 PF13654.6 KKK19423.1 - 0.003 16.4 0.3 1.2 7.8 0.0 2.1 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 KKK19423.1 - 0.0078 16.6 0.0 0.016 15.6 0.0 1.6 1 0 0 1 1 1 1 RNA helicase Clusterin PF01093.17 KKK19423.1 - 0.046 12.8 3.1 0.066 12.3 3.1 1.1 1 0 0 1 1 1 0 Clusterin DUF5344 PF17279.2 KKK19423.1 - 0.048 14.2 1.6 0.085 13.4 1.6 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5344) Nsp1_C PF05064.13 KKK19423.1 - 0.067 13.0 4.4 0.17 11.7 4.4 1.7 1 1 0 1 1 1 0 Nsp1-like C-terminal region AAA_19 PF13245.6 KKK19423.1 - 0.074 13.4 0.0 0.21 11.9 0.0 1.6 2 0 0 2 2 2 0 AAA domain Peptidase_C39 PF03412.15 KKK19423.1 - 0.11 12.3 0.3 0.26 11.1 0.3 1.6 1 0 0 1 1 1 0 Peptidase C39 family Ploopntkinase3 PF18751.1 KKK19423.1 - 0.15 12.0 0.0 0.39 10.6 0.0 1.7 1 1 1 2 2 2 0 P-loop Nucleotide Kinase3 PIG-Y PF15159.6 KKK19424.1 - 5.7e-23 81.6 8.7 9.9e-23 80.9 8.7 1.4 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y DUF1218 PF06749.12 KKK19424.1 - 0.042 14.4 1.8 5.1 7.7 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1218) Paxillin PF03535.13 KKK19424.1 - 0.087 12.7 0.3 0.087 12.7 0.3 2.2 2 0 0 2 2 2 0 Paxillin family K_channel_TID PF07941.11 KKK19424.1 - 2.9 8.4 10.7 0.081 13.4 3.2 2.3 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain GATase_4 PF13230.6 KKK19425.1 - 2.8e-12 46.1 0.0 5.3e-12 45.2 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferases class-II GATase_6 PF13522.6 KKK19425.1 - 8.9e-09 35.6 0.0 1.5e-08 34.9 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pyr_redox_2 PF07992.14 KKK19426.1 - 6.8e-52 176.5 0.1 8.6e-52 176.2 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KKK19426.1 - 1.9e-10 41.1 0.0 4.6e-09 36.7 0.1 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KKK19426.1 - 0.00017 21.0 0.1 0.099 11.9 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 KKK19426.1 - 0.31 11.5 4.3 7.3 7.1 0.0 3.6 3 1 0 3 3 3 0 Putative NAD(P)-binding RRM_1 PF00076.22 KKK19427.1 - 1.8e-40 136.6 0.0 1.8e-21 75.7 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KKK19427.1 - 2.9e-05 23.8 0.0 0.0019 18.0 0.0 2.3 2 1 0 2 2 2 1 Occluded RNA-recognition motif Nup35_RRM PF05172.13 KKK19427.1 - 0.0089 16.0 0.0 1.8 8.6 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 KKK19427.1 - 0.014 15.0 0.0 0.87 9.2 0.0 2.2 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KKK19427.1 - 0.052 13.7 0.0 0.41 10.8 0.0 2.3 2 1 0 2 2 2 0 RNA recognition motif Dynamin_N PF00350.23 KKK19428.1 - 1.6e-44 151.9 0.0 3.1e-44 151.0 0.0 1.5 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 KKK19428.1 - 5.4e-15 55.4 0.0 4.8e-12 45.7 0.0 2.4 2 0 0 2 2 2 2 Dynamin central region MMR_HSR1 PF01926.23 KKK19428.1 - 4.5e-05 23.5 0.0 0.00012 22.1 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase Zeta_toxin PF06414.12 KKK19428.1 - 0.015 14.6 0.1 2.3 7.4 0.0 2.9 3 0 0 3 3 3 0 Zeta toxin AAA_16 PF13191.6 KKK19428.1 - 0.023 15.1 0.5 0.24 11.8 0.0 2.8 3 1 0 3 3 3 0 AAA ATPase domain AAA_15 PF13175.6 KKK19428.1 - 0.029 14.1 0.4 0.21 11.2 0.1 2.3 2 1 0 2 2 2 0 AAA ATPase domain phiKZ_IP PF12699.7 KKK19428.1 - 0.05 12.7 0.2 0.13 11.4 0.0 1.7 2 0 0 2 2 2 0 phiKZ-like phage internal head proteins AAA_21 PF13304.6 KKK19428.1 - 0.059 13.2 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system Sugar_tr PF00083.24 KKK19430.1 - 3.1e-36 125.2 1.9 3.6e-36 125.0 1.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKK19430.1 - 4.6e-10 38.9 20.1 8e-10 38.2 20.2 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 KKK19430.1 - 0.00083 18.3 2.4 0.0013 17.7 2.4 1.2 1 0 0 1 1 1 1 MFS_1 like family OppC_N PF12911.7 KKK19430.1 - 0.094 12.7 7.4 2.1 8.4 0.1 2.6 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C KH_1 PF00013.29 KKK19431.1 - 9.3e-42 140.7 6.3 1.6e-16 59.9 0.1 3.3 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 KKK19431.1 - 4.6e-10 39.2 8.0 0.0018 18.1 0.1 3.4 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 KKK19431.1 - 2.1e-07 30.7 7.6 0.045 13.6 0.2 3.3 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 KKK19431.1 - 0.0003 20.8 6.0 0.43 10.7 0.1 3.5 3 0 0 3 3 3 2 NusA-like KH domain MOEP19 PF16005.5 KKK19431.1 - 0.039 14.0 0.0 30 4.7 0.0 3.1 3 0 0 3 3 3 0 KH-like RNA-binding domain ECR1_N PF14382.6 KKK19431.1 - 0.061 13.1 0.0 0.17 11.7 0.0 1.7 1 0 0 1 1 1 0 Exosome complex exonuclease RRP4 N-terminal region GARS_C PF02843.16 KKK19431.1 - 0.063 13.6 0.1 0.35 11.2 0.0 2.3 3 0 0 3 3 3 0 Phosphoribosylglycinamide synthetase, C domain ECF-ribofla_trS PF07155.12 KKK19431.1 - 0.065 13.2 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 ECF-type riboflavin transporter, S component zf-CCCH PF00642.24 KKK19432.1 - 0.0004 20.2 18.4 0.0007 19.4 1.0 3.8 4 0 0 4 4 4 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KKK19432.1 - 0.00093 19.2 4.7 0.00093 19.2 4.7 4.2 4 0 0 4 4 4 1 Zinc finger domain Torus PF16131.5 KKK19432.1 - 0.0022 18.7 0.1 0.0022 18.7 0.1 2.7 3 0 0 3 3 3 1 Torus domain zf-CCCH_4 PF18044.1 KKK19432.1 - 0.0067 16.2 1.9 0.0067 16.2 1.9 4.3 4 1 0 4 4 4 1 CCCH-type zinc finger SHE3 PF17078.5 KKK19432.1 - 0.087 12.5 1.1 0.13 12.0 1.1 1.2 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 Dor1 PF04124.12 KKK19432.1 - 0.13 11.0 0.3 0.19 10.3 0.3 1.1 1 0 0 1 1 1 0 Dor1-like family CENP-Q PF13094.6 KKK19432.1 - 2.2 8.5 4.7 6 7.0 3.9 1.9 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit ADH_N PF08240.12 KKK19433.1 - 6.9e-28 96.7 1.2 1.6e-27 95.6 1.2 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KKK19433.1 - 7.9e-14 51.8 0.0 2.5e-13 50.1 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Pyr_redox_2 PF07992.14 KKK19433.1 - 4.7e-13 49.0 0.1 2.1e-05 23.9 0.0 4.5 3 2 2 5 5 5 3 Pyridine nucleotide-disulphide oxidoreductase Glu_dehyd_C PF16912.5 KKK19433.1 - 2.7e-08 33.5 1.6 4e-06 26.5 0.4 3.6 1 1 2 3 3 3 1 Glucose dehydrogenase C-terminus Pyr_redox_3 PF13738.6 KKK19433.1 - 6.9e-05 22.2 0.0 0.29 10.3 0.0 3.6 4 0 0 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KKK19433.1 - 8.3e-05 22.7 2.6 0.0062 16.7 0.0 3.0 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KKK19433.1 - 0.00023 21.2 0.0 0.028 14.4 0.0 3.4 3 1 0 3 3 3 1 FAD-NAD(P)-binding FMO-like PF00743.19 KKK19433.1 - 0.0031 16.0 0.0 0.038 12.4 0.0 2.6 4 0 0 4 4 4 1 Flavin-binding monooxygenase-like HI0933_like PF03486.14 KKK19433.1 - 0.0047 15.7 1.1 4.8 5.8 0.3 3.1 3 0 0 3 3 3 2 HI0933-like protein ADH_zinc_N_2 PF13602.6 KKK19433.1 - 0.0048 18.0 0.0 0.014 16.5 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase K_oxygenase PF13434.6 KKK19433.1 - 0.12 11.5 0.0 0.4 9.8 0.0 1.9 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 KKK19433.1 - 0.2 12.2 3.2 10 6.7 0.0 2.8 3 0 0 3 3 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KKK19433.1 - 0.43 10.1 9.4 3.3 7.2 0.3 3.4 3 1 0 4 4 4 0 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 KKK19433.1 - 0.57 9.4 6.8 2.6 7.3 0.1 2.9 4 0 0 4 4 4 0 Alanine dehydrogenase/PNT, C-terminal domain Transketolase_N PF00456.21 KKK19434.1 - 2.5e-122 408.0 0.0 1.2e-121 405.7 0.0 1.9 1 1 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 KKK19434.1 - 2.4e-39 134.8 0.1 5.4e-39 133.7 0.1 1.6 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KKK19434.1 - 2.7e-07 30.5 0.0 6.2e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 KKK19434.1 - 3.6e-06 26.4 0.0 6.1e-05 22.4 0.0 2.1 1 1 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.20 KKK19434.1 - 1e-05 24.7 0.0 1.9e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 KKK19434.1 - 1.5e-05 24.9 1.0 0.0003 20.6 0.7 2.9 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Rpp20 PF12328.8 KKK19434.1 - 0.24 11.4 0.0 0.42 10.6 0.0 1.3 1 0 0 1 1 1 0 Rpp20 subunit of nuclear RNase MRP and P GMC_oxred_N PF00732.19 KKK19436.1 - 6.6e-61 206.3 0.0 9.1e-61 205.8 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KKK19436.1 - 2.9e-36 125.1 0.1 5.5e-36 124.2 0.1 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KKK19436.1 - 3.1e-07 29.9 0.0 0.0091 15.1 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 KKK19436.1 - 0.0018 17.9 0.4 0.083 12.5 0.1 2.9 3 1 0 3 3 3 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KKK19436.1 - 0.012 14.7 0.0 0.017 14.2 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Thi4 PF01946.17 KKK19436.1 - 0.014 14.7 0.1 0.032 13.5 0.1 1.5 1 0 0 1 1 1 0 Thi4 family NAD_binding_8 PF13450.6 KKK19436.1 - 0.037 14.3 0.1 0.11 12.7 0.1 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KKK19436.1 - 0.056 14.0 0.0 9 6.9 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Phosphoesterase PF04185.14 KKK19437.1 - 8.6e-71 239.0 0.1 1.1e-70 238.6 0.1 1.1 1 0 0 1 1 1 1 Phosphoesterase family Pkinase_fungal PF17667.1 KKK19438.1 - 1.7e-133 445.4 0.1 2.2e-133 445.0 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 KKK19438.1 - 0.00054 19.4 0.0 1.1 8.5 0.0 2.6 3 0 0 3 3 3 2 Protein kinase domain WaaY PF06176.11 KKK19438.1 - 0.01 15.5 0.0 0.028 14.1 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide core biosynthesis protein (WaaY) MauJ PF17419.2 KKK19438.1 - 0.011 15.3 0.0 0.018 14.5 0.0 1.3 1 0 0 1 1 1 0 Methylamine utilization protein MauJ APH PF01636.23 KKK19438.1 - 0.016 15.2 0.3 0.35 10.7 0.0 2.6 3 0 0 3 3 3 0 Phosphotransferase enzyme family MFS_1 PF07690.16 KKK19439.1 - 2.2e-40 138.7 46.2 2.2e-40 138.7 46.2 3.9 3 1 0 3 3 3 1 Major Facilitator Superfamily Xan_ur_permease PF00860.20 KKK19439.1 - 9.1e-19 67.4 30.5 1.1e-13 50.7 15.2 4.6 5 1 0 5 5 5 2 Permease family Abhydrolase_3 PF07859.13 KKK19440.1 - 4.2e-23 82.3 0.1 6.3e-23 81.7 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KKK19440.1 - 1.6e-17 63.4 0.0 2.2e-17 63.0 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 KKK19440.1 - 0.033 13.7 0.0 0.12 11.8 0.0 1.8 2 0 0 2 2 2 0 Prolyl oligopeptidase family Zn_clus PF00172.18 KKK19441.1 - 1.5e-07 31.4 9.1 3.2e-07 30.4 9.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CorA PF01544.18 KKK19442.1 - 0.0001 21.8 11.7 0.00023 20.6 11.7 1.7 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein NAD_binding_6 PF08030.12 KKK19443.1 - 4.8e-07 30.0 0.0 0.00026 21.2 0.0 2.2 1 1 0 2 2 2 2 Ferric reductase NAD binding domain NAD_binding_1 PF00175.21 KKK19443.1 - 2.5e-05 24.9 0.0 0.11 13.2 0.0 2.5 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain Pantoate_ligase PF02569.15 KKK19443.1 - 0.16 11.2 0.0 0.25 10.5 0.0 1.2 1 0 0 1 1 1 0 Pantoate-beta-alanine ligase Epimerase PF01370.21 KKK19444.1 - 7.2e-08 32.2 0.0 0.0062 16.0 0.0 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KKK19444.1 - 5.2e-06 26.5 0.1 8.9e-06 25.7 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 KKK19444.1 - 9.6e-05 21.7 0.0 0.00015 21.0 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Semialdhyde_dh PF01118.24 KKK19444.1 - 0.00013 22.4 0.0 0.0003 21.2 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NmrA PF05368.13 KKK19444.1 - 0.00017 21.2 0.1 0.00029 20.5 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family DXP_reductoisom PF02670.16 KKK19444.1 - 0.012 16.3 0.0 0.02 15.6 0.0 1.6 1 1 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Polysacc_synt_2 PF02719.15 KKK19444.1 - 0.094 11.8 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein GATA PF00320.27 KKK19445.1 - 3.7e-16 58.4 5.2 7.3e-16 57.5 5.2 1.5 1 0 0 1 1 1 1 GATA zinc finger PAS_3 PF08447.12 KKK19445.1 - 1.4e-05 25.3 0.0 0.00015 22.0 0.0 2.2 2 0 0 2 2 2 1 PAS fold PAS PF00989.25 KKK19445.1 - 5e-05 23.3 0.0 0.00046 20.2 0.0 2.3 2 0 0 2 2 2 1 PAS fold PAS_4 PF08448.10 KKK19445.1 - 0.0051 17.1 0.0 0.019 15.2 0.0 1.9 2 0 0 2 2 2 1 PAS fold Zn-ribbon_8 PF09723.10 KKK19445.1 - 0.0056 16.8 0.4 0.013 15.6 0.4 1.6 1 0 0 1 1 1 1 Zinc ribbon domain PAS_9 PF13426.7 KKK19445.1 - 0.012 15.8 0.0 0.09 13.0 0.0 2.2 2 0 0 2 2 2 0 PAS domain DUF5305 PF17231.2 KKK19446.1 - 0.01 15.3 0.5 0.019 14.4 0.1 1.6 2 0 0 2 2 2 1 Family of unknown function (DUF5305) Tetraspanin PF00335.20 KKK19446.1 - 0.089 12.5 0.1 0.56 9.9 0.1 2.0 2 0 0 2 2 2 0 Tetraspanin family SUR7 PF06687.12 KKK19446.1 - 0.094 12.3 5.9 3.3 7.3 0.2 2.2 1 1 1 2 2 2 0 SUR7/PalI family Shisa PF13908.6 KKK19446.1 - 0.1 12.8 1.2 0.18 12.0 0.2 2.0 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator Baculo_11_kDa PF06143.11 KKK19446.1 - 0.12 12.0 2.7 5.6 6.6 0.4 3.0 3 0 0 3 3 3 0 Baculovirus 11 kDa family AA_permease PF00324.21 KKK19447.1 - 7.3e-83 278.8 42.3 4.4e-58 197.0 22.7 2.0 1 1 1 2 2 2 2 Amino acid permease AA_permease_2 PF13520.6 KKK19447.1 - 3.5e-20 72.3 46.6 3.5e-17 62.3 25.6 2.1 1 1 1 2 2 2 2 Amino acid permease PAN_4 PF14295.6 KKK19449.1 - 2.4e-07 30.5 31.7 0.0075 16.2 5.7 5.1 4 0 0 4 4 4 4 PAN domain PAN_3 PF08277.12 KKK19449.1 - 0.00016 21.4 33.7 0.0069 16.2 2.5 5.2 5 0 0 5 5 5 3 PAN-like domain PAN_2 PF08276.11 KKK19449.1 - 0.1 12.7 34.5 1.6 8.9 5.6 4.9 4 0 0 4 4 4 0 PAN-like domain PAPS_reduct PF01507.19 KKK19465.1 - 9.5e-44 149.5 0.1 2.2e-43 148.3 0.0 1.6 2 0 0 2 2 2 1 Phosphoadenosine phosphosulfate reductase family HAD PF12710.7 KKK19466.1 - 1.5e-19 71.2 0.0 2e-19 70.7 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KKK19466.1 - 5.9e-18 65.9 0.1 8.1e-18 65.5 0.1 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KKK19466.1 - 6.1e-08 32.7 0.0 2.2e-06 27.6 0.0 2.6 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 KKK19466.1 - 5e-05 22.8 0.0 0.0002 20.8 0.0 1.8 1 1 0 1 1 1 1 Putative Phosphatase HAD_2 PF13419.6 KKK19466.1 - 0.00033 20.8 0.2 0.22 11.6 0.0 2.7 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase DUF705 PF05152.12 KKK19466.1 - 0.011 15.2 0.1 0.016 14.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF705) S6PP PF05116.13 KKK19466.1 - 0.025 14.1 0.1 0.28 10.7 0.0 2.1 2 0 0 2 2 2 0 Sucrose-6F-phosphate phosphohydrolase DUF2841 PF11001.8 KKK19467.1 - 1.5e-49 167.2 0.5 2.3e-49 166.5 0.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) zf-C2H2 PF00096.26 KKK19477.1 - 8.9e-05 22.7 2.7 0.15 12.6 0.4 3.7 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KKK19477.1 - 0.00054 20.6 1.1 2.6 9.1 0.0 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KKK19477.1 - 0.084 13.3 0.0 0.24 11.9 0.0 1.8 1 0 0 1 1 1 0 Zinc-finger double domain NR_Repeat PF14046.6 KKK19477.1 - 1.7 8.8 6.8 1.1 9.4 0.4 3.2 2 1 0 2 2 2 0 Nuclear receptor repeat GTP_EFTU PF00009.27 KKK19478.1 - 9e-09 35.1 0.0 2.1e-08 33.9 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.17 KKK19478.1 - 0.003 17.4 0.1 0.043 13.6 0.0 2.2 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein RsgA_GTPase PF03193.16 KKK19478.1 - 0.013 15.4 1.1 2.3 8.1 0.0 2.9 2 1 1 3 3 3 0 RsgA GTPase ABC_tran PF00005.27 KKK19478.1 - 0.044 14.3 0.1 0.093 13.2 0.1 1.5 1 0 0 1 1 1 0 ABC transporter F-box-like PF12937.7 KKK19479.1 - 0.00018 21.3 0.1 0.00065 19.6 0.1 2.0 1 0 0 1 1 1 1 F-box-like Fungal_trans PF04082.18 KKK19480.1 - 2.6e-21 75.8 0.0 4.6e-21 75.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK19480.1 - 2.8e-08 33.7 12.9 4.4e-08 33.1 12.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DHquinase_I PF01487.15 KKK19481.1 - 3.9e-35 122.2 0.0 6e-35 121.5 0.0 1.3 1 0 0 1 1 1 1 Type I 3-dehydroquinase Shikimate_dh_N PF08501.11 KKK19481.1 - 1.3e-20 73.5 0.1 2.6e-20 72.5 0.1 1.5 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain SKI PF01202.22 KKK19481.1 - 3.5e-19 69.5 0.5 6.3e-19 68.7 0.0 1.7 2 0 0 2 2 2 1 Shikimate kinase Shikimate_DH PF01488.20 KKK19481.1 - 5.2e-07 29.8 0.0 1.4e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase AAA_28 PF13521.6 KKK19481.1 - 0.0014 18.9 0.0 0.0028 17.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KKK19481.1 - 0.0096 16.1 0.0 0.02 15.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KKK19481.1 - 0.023 15.1 0.1 0.4 11.1 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain F420_oxidored PF03807.17 KKK19481.1 - 0.065 13.8 0.0 1.8 9.2 0.0 2.5 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent CoaE PF01121.20 KKK19481.1 - 0.083 12.6 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 Dephospho-CoA kinase AAA PF00004.29 KKK19481.1 - 0.18 12.2 0.0 0.33 11.4 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Complex1_LYR PF05347.15 KKK19500.1 - 4.2e-15 55.6 0.5 6.1e-15 55.0 0.5 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KKK19500.1 - 1.1e-08 35.7 0.4 1.6e-08 35.2 0.4 1.2 1 0 0 1 1 1 1 Complex1_LYR-like DUF2119 PF09892.9 KKK19500.1 - 0.058 12.8 0.0 0.076 12.4 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2119) HIG_1_N PF04588.13 KKK19501.1 - 2.9e-27 94.6 0.3 4e-27 94.2 0.3 1.2 1 0 0 1 1 1 1 Hypoxia induced protein conserved region DUF2514 PF10721.9 KKK19501.1 - 0.03 14.4 4.3 0.043 13.8 4.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) Syja_N PF02383.18 KKK19502.1 - 1.1e-90 304.2 0.0 1.6e-90 303.7 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain Mur_ligase_M PF08245.12 KKK19502.1 - 2.5e-05 24.3 0.2 0.0094 16.0 0.0 3.1 1 1 1 2 2 2 2 Mur ligase middle domain Abhydrolase_6 PF12697.7 KKK19503.1 - 6.8e-09 36.6 2.7 1e-08 36.1 2.7 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KKK19503.1 - 1.7e-05 24.3 0.0 7.6e-05 22.1 0.0 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 KKK19503.1 - 3.2e-05 23.9 0.0 5.2e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.20 KKK19503.1 - 0.00023 20.9 0.0 0.00038 20.2 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KKK19503.1 - 0.031 13.7 0.0 3.1 7.2 0.0 2.3 2 0 0 2 2 2 0 Prolyl oligopeptidase family GTP_EFTU PF00009.27 KKK19504.1 - 1.1e-58 198.1 0.3 1.8e-58 197.3 0.3 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 KKK19504.1 - 9.1e-34 115.8 0.0 2e-33 114.7 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.6 KKK19504.1 - 1e-32 112.1 0.0 2.3e-32 110.9 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 KKK19504.1 - 5.5e-23 80.8 0.0 1.2e-22 79.7 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KKK19504.1 - 2.3e-11 43.9 0.1 5.7e-11 42.7 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 KKK19504.1 - 7.1e-06 25.9 0.0 1.7e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain MMR_HSR1 PF01926.23 KKK19504.1 - 0.17 12.0 0.0 0.37 10.9 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase NMT_C PF02799.15 KKK19505.1 - 4.2e-87 291.1 0.1 7.2e-87 290.3 0.1 1.4 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.19 KKK19505.1 - 2.7e-74 248.4 0.7 2e-73 245.5 0.1 2.1 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_9 PF13527.7 KKK19505.1 - 6.4e-06 26.3 0.1 0.00016 21.8 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KKK19505.1 - 0.014 15.6 0.0 0.026 14.7 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family NTP_transf_9 PF04248.12 KKK19505.1 - 0.08 12.8 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF427) TFB6 PF17110.5 KKK19506.1 - 0.95 9.2 3.5 0.56 9.9 0.1 2.1 2 0 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH Glycos_transf_1 PF00534.20 KKK19526.1 - 9.8e-12 44.7 0.0 2.6e-11 43.3 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KKK19526.1 - 1.9e-11 44.6 0.0 4.1e-11 43.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 DUF3492 PF11997.8 KKK19526.1 - 0.0066 16.2 0.0 0.02 14.6 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3492) GPI-anchored PF10342.9 KKK19528.1 - 8.8e-18 64.9 2.5 1e-17 64.6 2.5 1.1 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family LT-IIB PF06453.11 KKK19528.1 - 0.051 13.5 0.0 0.061 13.2 0.0 1.2 1 0 0 1 1 1 0 Type II heat-labile enterotoxin , B subunit (LT-IIB) RE_ApaLI PF09499.10 KKK19528.1 - 0.082 12.6 0.0 0.099 12.3 0.0 1.3 1 0 0 1 1 1 0 ApaLI-like restriction endonuclease RL11D PF11088.8 KKK19528.1 - 0.12 12.6 0.3 0.23 11.7 0.1 1.5 2 0 0 2 2 2 0 Glycoprotein encoding membrane proteins RL5A and RL6 adh_short_C2 PF13561.6 KKK19538.1 - 2.7e-55 187.5 0.3 6.2e-55 186.3 0.3 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KKK19538.1 - 2.1e-33 115.5 0.5 1.9e-32 112.3 0.5 2.0 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KKK19538.1 - 1.8e-07 31.3 0.3 4.9e-06 26.6 0.0 2.1 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 KKK19538.1 - 0.0023 17.4 0.1 0.013 15.0 0.0 1.9 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.19 KKK19538.1 - 0.019 14.3 0.0 0.033 13.5 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.16 KKK19538.1 - 0.091 12.4 0.1 0.13 11.9 0.1 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Cadherin_C_2 PF16492.5 KKK19539.1 - 0.076 13.8 0.2 0.28 11.9 0.2 2.0 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal Metallophos PF00149.28 KKK19540.1 - 1.5e-36 126.8 0.5 2.7e-36 126.0 0.1 1.6 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Voldacs PF03517.13 KKK19541.1 - 2.7e-25 89.1 1.1 6e-25 88.0 0.1 2.1 3 0 0 3 3 3 1 Regulator of volume decrease after cellular swelling Opi1 PF08618.10 KKK19543.1 - 0.00071 18.9 0.5 0.00071 18.9 0.5 2.2 1 1 0 2 2 2 1 Transcription factor Opi1 DUF3439 PF11921.8 KKK19543.1 - 0.49 10.4 8.6 0.93 9.5 8.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Dicty_REP PF05086.12 KKK19543.1 - 1.5 6.7 2.7 1.7 6.5 2.7 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein MFS_1 PF07690.16 KKK19544.1 - 2.2e-30 105.8 17.7 7.8e-30 104.0 17.7 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 KKK19544.1 - 4.9e-06 26.1 5.8 4.9e-06 26.1 5.8 1.9 2 2 1 3 3 3 1 Uncharacterised MFS-type transporter YbfB RdRP PF05183.12 KKK19545.1 - 2.2e-133 446.0 0.0 2.9e-133 445.6 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase AA_permease PF00324.21 KKK19546.1 - 4.9e-78 262.8 30.2 6.2e-78 262.5 30.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KKK19546.1 - 1.1e-22 80.5 31.3 1.4e-22 80.1 31.3 1.1 1 0 0 1 1 1 1 Amino acid permease Ribosomal_L19 PF01245.20 KKK19547.1 - 1e-15 57.6 0.4 1.9e-15 56.8 0.4 1.4 1 0 0 1 1 1 1 Ribosomal protein L19 NmrA PF05368.13 KKK19548.1 - 4e-29 101.8 0.0 4.9e-29 101.5 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KKK19548.1 - 5e-16 59.1 0.0 9.2e-16 58.3 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 KKK19548.1 - 9.7e-07 29.1 0.0 1.9e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 KKK19548.1 - 1.9e-05 25.1 0.0 5e-05 23.7 0.0 1.7 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 KKK19548.1 - 0.00062 19.8 0.2 0.0018 18.4 0.0 1.8 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.21 KKK19548.1 - 0.057 12.9 0.0 0.39 10.1 0.0 2.3 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family DapB_N PF01113.20 KKK19548.1 - 0.1 12.8 0.0 0.2 11.8 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Ion_trans_2 PF07885.16 KKK19549.1 - 3.9e-25 87.6 30.2 5.9e-15 55.0 7.9 3.5 3 1 0 3 3 3 2 Ion channel Ion_trans PF00520.31 KKK19549.1 - 0.00072 18.9 0.3 0.00072 18.9 0.3 3.6 2 1 0 3 3 3 2 Ion transport protein DUF1345 PF07077.11 KKK19549.1 - 0.033 13.9 2.5 2.9 7.5 0.0 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1345) Opi1 PF08618.10 KKK19550.1 - 7.6e-39 134.1 2.0 1.1e-27 97.4 0.2 2.1 1 1 1 2 2 2 2 Transcription factor Opi1 KLRAQ PF10205.9 KKK19550.1 - 0.042 14.1 0.1 0.37 11.1 0.0 2.1 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein DUF3631 PF12307.8 KKK19550.1 - 0.07 13.3 0.1 0.11 12.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3631) Globin PF00042.22 KKK19550.1 - 0.12 13.0 0.1 0.19 12.3 0.1 1.3 1 0 0 1 1 1 0 Globin Bystin PF05291.11 KKK19550.1 - 0.16 11.2 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 Bystin Ank_2 PF12796.7 KKK19551.1 - 1.4e-39 134.5 5.4 2e-11 44.3 0.0 4.2 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KKK19551.1 - 8e-29 99.6 10.2 1.8e-08 34.7 0.2 5.1 5 0 0 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KKK19551.1 - 7.4e-28 93.5 11.0 0.00052 20.3 0.1 8.3 8 0 0 8 8 8 6 Ankyrin repeat Ank PF00023.30 KKK19551.1 - 1.9e-26 91.3 25.6 1.2e-05 25.5 0.1 8.2 7 1 1 8 8 8 7 Ankyrin repeat Ank_5 PF13857.6 KKK19551.1 - 2.9e-25 88.0 19.0 1.6e-05 25.1 0.1 8.0 2 2 7 9 9 9 6 Ankyrin repeats (many copies) RVP PF00077.20 KKK19551.1 - 0.094 13.0 0.1 41 4.6 0.0 4.0 5 0 0 5 5 5 0 Retroviral aspartyl protease DUF4419 PF14388.6 KKK19552.1 - 4.1e-87 292.4 0.1 5.4e-87 292.0 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4419) TFA2_Winged_2 PF18121.1 KKK19553.1 - 4.3e-22 77.6 0.4 1.1e-21 76.3 0.4 1.7 1 0 0 1 1 1 1 TFA2 Winged helix domain 2 TFIIE_beta PF02186.15 KKK19553.1 - 1.9e-20 72.9 0.0 7.8e-20 70.9 0.0 2.1 2 0 0 2 2 2 1 TFIIE beta subunit core domain TPR_MLP1_2 PF07926.12 KKK19554.1 - 5e-33 113.9 35.9 5e-33 113.9 35.9 17.7 9 5 7 17 17 17 5 TPR/MLP1/MLP2-like protein KASH_CCD PF14662.6 KKK19554.1 - 0.0019 18.0 31.2 0.0019 18.0 31.2 14.2 7 3 7 14 14 14 3 Coiled-coil region of CCDC155 or KASH CENP-F_leu_zip PF10473.9 KKK19554.1 - 0.0072 16.4 5.0 0.0072 16.4 5.0 15.8 7 3 10 17 17 17 6 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 APC_N_CC PF16689.5 KKK19554.1 - 0.063 13.4 0.0 0.063 13.4 0.0 11.1 13 0 0 13 13 13 0 Coiled-coil N-terminus of APC, dimerisation domain Wzy_C_2 PF11846.8 KKK19554.1 - 0.12 12.3 2.2 0.86 9.5 2.2 2.6 1 0 0 1 1 1 0 Virulence factor membrane-bound polymerase, C-terminal ASF1_hist_chap PF04729.13 KKK19555.1 - 1.3e-73 246.1 0.0 1.7e-73 245.6 0.0 1.2 1 0 0 1 1 1 1 ASF1 like histone chaperone Nop14 PF04147.12 KKK19555.1 - 0.006 14.9 24.5 0.0079 14.5 24.5 1.0 1 0 0 1 1 1 1 Nop14-like family Suf PF05843.14 KKK19556.1 - 1.3e-97 327.4 0.2 1.3e-97 327.4 0.2 4.3 4 1 1 5 5 5 2 Suppressor of forked protein (Suf) TPR_14 PF13428.6 KKK19556.1 - 2.1e-05 25.0 0.0 0.013 16.3 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat HAT PF02184.16 KKK19556.1 - 0.0063 16.5 0.1 0.0063 16.5 0.1 2.4 2 0 0 2 2 2 1 HAT (Half-A-TPR) repeat DUF5583 PF17821.1 KKK19556.1 - 0.043 13.8 0.4 0.043 13.8 0.4 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5583) Lgl_C PF08596.10 KKK19557.1 - 5.7e-136 453.3 0.0 1.2e-135 452.2 0.0 1.6 2 0 0 2 2 2 1 Lethal giant larvae(Lgl) like, C-terminal ANAPC4_WD40 PF12894.7 KKK19557.1 - 1.1e-06 28.8 0.0 9.5 6.6 0.0 5.9 5 2 1 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KKK19557.1 - 9.5e-06 26.3 4.6 0.23 12.4 0.1 5.7 6 0 0 6 6 6 2 WD domain, G-beta repeat APH PF01636.23 KKK19558.1 - 0.0014 18.6 0.1 0.002 18.1 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family PS-DH PF14765.6 KKK19559.1 - 8e-52 176.3 0.9 1.4e-51 175.5 0.9 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.10 KKK19559.1 - 2.9e-51 173.9 0.5 2e-50 171.2 0.1 2.4 2 0 0 2 2 2 1 KR domain adh_short PF00106.25 KKK19559.1 - 3.6e-12 46.2 0.2 2.3e-11 43.5 0.0 2.3 3 0 0 3 3 3 1 short chain dehydrogenase PP-binding PF00550.25 KKK19559.1 - 1.7e-05 25.1 0.1 4.3e-05 23.8 0.1 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site DUF617 PF04759.13 KKK19559.1 - 0.17 11.9 0.0 65 3.5 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function, DUF617 SAP PF02037.27 KKK19560.1 - 1.6e-10 40.4 0.3 3.5e-10 39.4 0.2 1.6 2 0 0 2 2 2 1 SAP domain RSB_motif PF16294.5 KKK19560.1 - 1.8e-07 31.3 0.0 1.8e-07 31.3 0.0 4.0 3 2 1 4 4 4 1 RNSP1-SAP18 binding (RSB) motif BTB PF00651.31 KKK19561.1 - 0.13 12.5 0.0 0.29 11.4 0.0 1.6 1 0 0 1 1 1 0 BTB/POZ domain Solute_trans_a PF03619.16 KKK19562.1 - 9.1e-87 290.9 23.8 1.1e-86 290.7 23.8 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Brr6_like_C_C PF10104.9 KKK19562.1 - 0.3 10.9 4.8 2.2 8.1 0.6 2.7 2 1 0 2 2 2 0 Di-sulfide bridge nucleocytoplasmic transport domain Glyco_hydro_3_C PF01915.22 KKK19564.1 - 9.6e-61 205.3 0.0 2.2e-60 204.1 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KKK19564.1 - 8.4e-49 166.7 0.0 1.4e-48 165.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KKK19564.1 - 2.1e-22 79.0 0.4 1.2e-21 76.6 0.4 2.2 2 0 0 2 2 2 1 Fibronectin type III-like domain PA14 PF07691.12 KKK19564.1 - 3.8e-15 56.0 0.0 7.2e-15 55.1 0.0 1.4 1 0 0 1 1 1 1 PA14 domain DUF11 PF01345.18 KKK19564.1 - 0.0051 17.1 1.1 0.042 14.1 1.1 2.3 2 0 0 2 2 2 1 Domain of unknown function DUF11 CARDB PF07705.11 KKK19564.1 - 0.025 14.8 0.1 0.063 13.5 0.1 1.6 1 0 0 1 1 1 0 CARDB Abhydrolase_1 PF00561.20 KKK19565.1 - 9.7e-51 172.9 0.0 2.4e-50 171.6 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KKK19565.1 - 6.6e-06 26.9 0.7 5.3e-05 23.9 0.7 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KKK19565.1 - 0.09 12.0 0.0 1.1 8.5 0.0 2.1 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Say1_Mug180 PF10340.9 KKK19565.1 - 0.13 11.1 0.0 0.2 10.5 0.0 1.2 1 0 0 1 1 1 0 Steryl acetyl hydrolase NDUFA12 PF05071.16 KKK19567.1 - 8.2e-31 106.7 0.9 1e-30 106.4 0.9 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 PLDc_2 PF13091.6 KKK19568.1 - 1.4e-09 37.9 0.0 2.3e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 PLD-like domain DnaG_DnaB_bind PF08278.11 KKK19568.1 - 0.0028 18.2 0.0 0.018 15.6 0.0 2.0 2 0 0 2 2 2 1 DNA primase DnaG DnaB-binding PLDc PF00614.22 KKK19568.1 - 0.0039 17.3 0.2 0.27 11.5 0.0 2.4 2 0 0 2 2 2 1 Phospholipase D Active site motif CysG_dimeriser PF10414.9 KKK19568.1 - 0.13 12.0 0.1 0.3 10.8 0.1 1.5 1 0 0 1 1 1 0 Sirohaem synthase dimerisation region Ras PF00071.22 KKK19574.1 - 5e-38 130.2 0.0 9.3e-38 129.4 0.0 1.4 1 1 0 1 1 1 1 Ras family Roc PF08477.13 KKK19574.1 - 2.1e-26 92.5 0.0 3.1e-26 91.9 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKK19574.1 - 1.9e-11 43.7 0.0 2.3e-10 40.2 0.0 2.0 2 0 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KKK19574.1 - 0.004 17.2 0.0 0.0065 16.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KKK19574.1 - 0.0088 15.4 0.0 0.012 15.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 KKK19574.1 - 0.019 14.9 0.0 0.082 12.8 0.0 2.0 3 0 0 3 3 3 0 RsgA GTPase AAA_16 PF13191.6 KKK19574.1 - 0.034 14.5 0.0 0.42 11.0 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_33 PF13671.6 KKK19574.1 - 0.076 13.2 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain SRPRB PF09439.10 KKK19574.1 - 0.11 11.9 0.0 0.19 11.1 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit ABC_tran PF00005.27 KKK19574.1 - 0.12 12.9 0.0 0.24 11.9 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_7 PF12775.7 KKK19574.1 - 0.14 11.6 0.0 0.24 10.9 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region PduV-EutP PF10662.9 KKK19574.1 - 0.14 11.9 0.0 7.9 6.2 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation UTP25 PF06862.12 KKK19575.1 - 5.9e-194 645.2 0.0 7.9e-194 644.8 0.0 1.1 1 0 0 1 1 1 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 MitMem_reg PF13012.6 KKK19576.1 - 1.6e-20 73.6 0.3 2.9e-20 72.7 0.3 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 KKK19576.1 - 2.2e-19 69.6 0.0 3.6e-19 68.9 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease UPF0172 PF03665.13 KKK19576.1 - 7.8e-05 22.8 0.0 0.00023 21.3 0.0 1.7 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0172) CTP_transf_like PF01467.26 KKK19577.1 - 2.2e-29 102.5 0.0 3.9e-29 101.7 0.0 1.4 1 0 0 1 1 1 1 Cytidylyltransferase-like PP2C PF00481.21 KKK19578.1 - 2.6e-81 273.0 0.0 4.3e-81 272.3 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C Roughex PF06020.11 KKK19578.1 - 0.066 12.3 5.9 0.1 11.7 5.9 1.2 1 0 0 1 1 1 0 Drosophila roughex protein EamA PF00892.20 KKK19579.1 - 7.2e-17 61.8 25.9 2.2e-09 37.6 1.3 3.4 4 0 0 4 4 4 3 EamA-like transporter family DUF4692 PF15763.5 KKK19579.1 - 0.0014 19.1 3.1 0.0027 18.2 3.1 1.4 1 0 0 1 1 1 1 Regulator of human erythroid cell expansion (RHEX) SR-25 PF10500.9 KKK19579.1 - 1.9 8.0 17.2 3.5 7.2 17.2 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein IMUP PF15761.5 KKK19579.1 - 9.2 7.0 13.8 18 6.1 13.8 1.4 1 0 0 1 1 1 0 Immortalisation up-regulated protein DUF1769 PF08588.10 KKK19586.1 - 2.6e-26 91.6 0.2 4.8e-26 90.7 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) AAA_13 PF13166.6 KKK19587.1 - 0.0015 17.3 0.2 0.0015 17.3 0.2 3.0 2 1 1 3 3 3 1 AAA domain Myosin_tail_1 PF01576.19 KKK19587.1 - 0.0033 15.3 40.9 0.026 12.4 2.1 3.4 3 0 0 3 3 3 3 Myosin tail Sec3_C_2 PF15278.6 KKK19587.1 - 0.0091 16.3 0.3 0.046 14.1 0.1 2.3 2 0 0 2 2 2 1 Sec3 exocyst complex subunit Fib_alpha PF08702.10 KKK19587.1 - 0.31 11.2 16.5 0.12 12.5 5.3 4.3 3 1 0 4 4 4 0 Fibrinogen alpha/beta chain family DUF465 PF04325.13 KKK19587.1 - 0.67 10.0 6.2 2 8.5 0.6 3.3 2 0 0 2 2 2 0 Protein of unknown function (DUF465) ADIP PF11559.8 KKK19587.1 - 2.5 8.1 37.2 0.17 11.9 0.1 4.4 3 1 2 5 5 5 0 Afadin- and alpha -actinin-Binding Ribosomal_S8 PF00410.19 KKK19588.1 - 6.3e-14 52.0 0.0 9e-13 48.3 0.0 2.2 1 1 0 1 1 1 1 Ribosomal protein S8 FAD_binding_3 PF01494.19 KKK19589.1 - 2.9e-16 59.7 0.0 7.3e-16 58.3 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KKK19589.1 - 0.00015 21.1 0.0 0.00026 20.4 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KKK19589.1 - 0.001 19.5 0.0 0.003 18.1 0.0 1.8 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KKK19589.1 - 0.0012 18.5 0.2 0.0027 17.4 0.2 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KKK19589.1 - 0.0023 18.1 0.0 0.0051 17.0 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KKK19589.1 - 0.0049 15.6 0.1 0.0075 15.0 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein AlaDh_PNT_C PF01262.21 KKK19589.1 - 0.014 14.7 0.0 0.021 14.1 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.7 KKK19589.1 - 0.037 13.4 3.1 0.13 11.6 0.6 2.3 3 0 0 3 3 3 0 FAD dependent oxidoreductase SE PF08491.10 KKK19589.1 - 0.039 13.0 0.0 0.053 12.6 0.0 1.2 1 0 0 1 1 1 0 Squalene epoxidase GIDA PF01134.22 KKK19589.1 - 0.068 12.2 0.1 0.12 11.5 0.1 1.5 1 1 0 1 1 1 0 Glucose inhibited division protein A FAD_binding_2 PF00890.24 KKK19589.1 - 0.092 11.8 0.2 0.24 10.4 0.1 1.6 2 0 0 2 2 2 0 FAD binding domain Fungal_trans PF04082.18 KKK19590.1 - 1.7e-05 24.0 0.0 3.4e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK19590.1 - 0.00033 20.7 10.3 0.00066 19.7 10.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_25 PF01183.20 KKK19591.1 - 1.3e-34 119.9 0.0 1.5e-34 119.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 25 Peptidase_M24 PF00557.24 KKK19592.1 - 2.4e-48 164.6 0.0 2.9e-48 164.3 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-C6H2 PF15801.5 KKK19592.1 - 1.3e-20 73.4 6.2 3.1e-20 72.2 6.2 1.6 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 KKK19592.1 - 0.00028 20.9 4.7 0.00028 20.9 4.7 2.1 2 0 0 2 2 2 1 MYND finger MFS_1 PF07690.16 KKK19593.1 - 7.2e-43 146.9 45.0 1.1e-42 146.2 45.0 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KKK19593.1 - 2.3e-13 49.8 9.6 2.3e-13 49.8 9.6 2.6 3 0 0 3 3 3 2 Sugar (and other) transporter EF-hand_1 PF00036.32 KKK19593.1 - 3.1e-13 48.2 1.3 3.5e-06 26.2 0.2 2.6 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 KKK19593.1 - 4.7e-12 46.2 8.6 1.9e-08 34.6 1.1 2.2 1 1 2 3 3 3 3 EF-hand domain pair ZZ PF00569.17 KKK19593.1 - 6.7e-12 45.0 4.2 1.2e-11 44.3 4.2 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type EF-hand_6 PF13405.6 KKK19593.1 - 5.5e-10 38.4 2.2 0.00026 20.7 0.1 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 KKK19593.1 - 3.8e-06 26.2 1.7 0.0055 16.1 0.2 2.6 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 KKK19593.1 - 5e-06 26.3 2.0 0.00011 21.9 0.7 2.5 1 1 1 2 2 2 2 EF-hand domain pair C1_2 PF03107.16 KKK19593.1 - 0.0099 16.2 4.0 0.019 15.3 4.0 1.4 1 0 0 1 1 1 1 C1 domain DUF3506 PF12014.8 KKK19594.1 - 5.6e-53 178.7 0.0 9.4e-53 177.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3506) F-box-like PF12937.7 KKK19594.1 - 4e-11 42.6 0.7 9.5e-11 41.4 0.7 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KKK19594.1 - 7.2e-08 32.1 0.1 8.3e-07 28.7 0.1 2.3 2 0 0 2 2 2 1 F-box domain Pyrid_ox_like PF16242.5 KKK19594.1 - 0.078 12.6 0.0 0.58 9.7 0.0 2.4 3 0 0 3 3 3 0 Pyridoxamine 5'-phosphate oxidase like DUF1748 PF08520.10 KKK19595.1 - 6.4e-36 122.1 0.1 7.2e-36 121.9 0.1 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) Iso_dh PF00180.20 KKK19598.1 - 2.9e-96 322.6 0.0 8.5e-96 321.1 0.0 1.6 1 1 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF1447 PF07288.11 KKK19598.1 - 0.12 12.4 0.1 0.32 11.1 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1447) AAA_lid_8 PF17868.1 KKK19599.1 - 0.21 11.5 2.0 15 5.6 0.1 2.6 2 0 0 2 2 2 0 AAA lid domain 3Beta_HSD PF01073.19 KKK19600.1 - 2.7e-53 180.8 0.0 3.4e-53 180.5 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KKK19600.1 - 4.3e-37 127.9 0.0 5.4e-37 127.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KKK19600.1 - 8.8e-20 71.4 0.0 1.8e-19 70.3 0.0 1.5 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 KKK19600.1 - 5.8e-17 61.7 0.0 7.8e-17 61.3 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 KKK19600.1 - 9.3e-12 44.6 0.0 2e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.15 KKK19600.1 - 3.3e-09 36.3 0.0 4.1e-08 32.7 0.1 2.4 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 KKK19600.1 - 3e-08 33.7 0.0 4.3e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding adh_short_C2 PF13561.6 KKK19600.1 - 0.00047 19.8 0.0 0.001 18.7 0.0 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KKK19600.1 - 0.00051 19.5 0.0 0.00097 18.6 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KKK19600.1 - 0.00073 19.5 0.2 0.0087 16.0 0.2 2.1 1 1 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 KKK19600.1 - 0.0014 18.9 0.0 0.0033 17.7 0.0 1.6 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NmrA PF05368.13 KKK19600.1 - 0.026 14.1 0.0 0.041 13.4 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family PK PF00224.21 KKK19602.1 - 5.8e-176 584.5 2.4 7.2e-176 584.2 2.4 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 KKK19602.1 - 1e-38 132.2 0.0 2.9e-38 130.7 0.0 1.8 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 KKK19602.1 - 0.00011 21.4 0.6 0.00027 20.2 0.3 1.7 1 1 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.25 KKK19602.1 - 0.052 12.5 0.0 0.47 9.4 0.0 2.1 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain Dcc1 PF09724.9 KKK19603.1 - 2.3e-20 73.2 0.0 4.4e-20 72.3 0.0 1.4 1 1 0 1 1 1 1 Sister chromatid cohesion protein Dcc1 FAM176 PF14851.6 KKK19603.1 - 0.0081 15.8 1.0 0.017 14.8 1.0 1.5 1 0 0 1 1 1 1 FAM176 family DUF4611 PF15387.6 KKK19603.1 - 0.022 15.0 3.6 0.052 13.8 3.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) RXT2_N PF08595.11 KKK19603.1 - 0.045 13.8 3.7 0.078 13.0 3.7 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal CENP-B_dimeris PF09026.10 KKK19603.1 - 0.065 13.6 10.5 0.15 12.5 10.5 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain NOA36 PF06524.12 KKK19603.1 - 0.39 10.0 6.7 0.58 9.4 6.7 1.2 1 0 0 1 1 1 0 NOA36 protein WRNPLPNID PF15017.6 KKK19603.1 - 0.92 10.4 7.7 0.42 11.5 4.1 2.1 2 0 0 2 2 2 0 Putative WW-binding domain and destruction box SH3_4 PF06347.13 KKK19603.1 - 2.4 8.1 5.6 0.43 10.5 0.2 2.7 3 1 0 3 3 3 0 Bacterial SH3 domain DNA_pol_phi PF04931.13 KKK19603.1 - 9 4.2 8.0 13 3.8 8.0 1.1 1 0 0 1 1 1 0 DNA polymerase phi Acetyltransf_7 PF13508.7 KKK19604.1 - 3.6e-06 27.3 0.0 6.8e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KKK19604.1 - 0.00018 21.7 0.1 0.00048 20.3 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 KKK19604.1 - 0.00027 21.0 0.1 0.0016 18.5 0.0 2.2 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KKK19604.1 - 0.0032 17.4 0.1 0.017 15.1 0.0 2.2 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_10 PF13673.7 KKK19604.1 - 0.0034 17.3 0.0 0.0074 16.2 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF5490 PF17593.2 KKK19604.1 - 0.037 14.0 1.1 0.088 12.8 1.1 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5490) Acetyltransf_15 PF17013.5 KKK19604.1 - 0.043 13.3 0.0 0.057 12.9 0.0 1.2 1 0 0 1 1 1 0 Putative acetyl-transferase Anp1 PF03452.14 KKK19605.1 - 6.9e-114 379.7 0.0 1.1e-113 379.1 0.0 1.3 1 0 0 1 1 1 1 Anp1 adh_short PF00106.25 KKK19605.1 - 1e-09 38.1 0.0 1.8e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KKK19605.1 - 4e-06 26.9 0.0 6.9e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 KR domain Glyco_tranf_2_4 PF13704.6 KKK19605.1 - 0.018 15.5 0.1 0.056 14.0 0.1 1.9 1 0 0 1 1 1 0 Glycosyl transferase family 2 IBR PF01485.21 KKK19606.1 - 7.9e-06 26.0 8.1 7.9e-06 26.0 8.1 3.5 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain DnaJ-X PF14308.6 KKK19625.1 - 2.8e-72 242.6 5.5 6.4e-72 241.4 5.5 1.6 1 0 0 1 1 1 1 X-domain of DnaJ-containing DnaJ PF00226.31 KKK19625.1 - 1.3e-25 89.2 0.1 3.5e-25 87.9 0.1 1.8 1 0 0 1 1 1 1 DnaJ domain SQS_PSY PF00494.19 KKK19626.1 - 2.1e-37 129.1 0.0 3.6e-37 128.3 0.0 1.4 1 0 0 1 1 1 1 Squalene/phytoene synthase Peroxin-22 PF12827.7 KKK19626.1 - 0.057 13.4 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Peroxisomal biogenesis protein family Hemerythrin PF01814.23 KKK19627.1 - 4.9e-06 27.2 0.2 8.5e-06 26.4 0.2 1.6 1 1 0 1 1 1 1 Hemerythrin HHE cation binding domain Peptidase_A4 PF01828.17 KKK19628.1 - 2.4e-68 229.7 12.6 3e-68 229.4 12.6 1.1 1 0 0 1 1 1 1 Peptidase A4 family S-methyl_trans PF02574.16 KKK19629.1 - 1.1e-53 182.8 0.0 1.3e-53 182.5 0.0 1.0 1 0 0 1 1 1 1 Homocysteine S-methyltransferase SRR1 PF07985.12 KKK19630.1 - 2.7e-11 43.3 0.0 5.8e-11 42.3 0.0 1.6 1 0 0 1 1 1 1 SRR1 Fas_alpha_ACP PF18325.1 KKK19631.1 - 1.5e-56 191.2 0.0 2.8e-56 190.3 0.0 1.4 1 0 0 1 1 1 1 Fatty acid synthase subunit alpha Acyl carrier domain FAS_I_H PF18314.1 KKK19631.1 - 1.6e-37 129.1 0.1 2.9e-37 128.3 0.1 1.4 1 0 0 1 1 1 1 Fatty acid synthase type I helical domain ketoacyl-synt PF00109.26 KKK19631.1 - 7.9e-19 68.2 0.0 1.6e-18 67.2 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 KKK19631.1 - 1.1e-16 61.0 0.0 2.4e-16 59.8 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ACPS PF01648.20 KKK19631.1 - 3.5e-13 49.7 0.0 7.6e-13 48.6 0.0 1.6 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily adh_short_C2 PF13561.6 KKK19631.1 - 0.00057 19.5 0.0 0.00097 18.8 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1729 PF08354.10 KKK19632.1 - 5.1e-143 476.2 0.0 8.3e-143 475.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) Acyl_transf_1 PF00698.21 KKK19632.1 - 6e-56 190.3 0.0 5.1e-55 187.2 0.0 2.3 2 1 0 2 2 2 1 Acyl transferase domain SAT PF16073.5 KKK19632.1 - 2.6e-25 89.6 0.0 4.5e-25 88.8 0.0 1.4 1 0 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis MaoC_dehydratas PF01575.19 KKK19632.1 - 1.6e-22 79.3 0.0 3.4e-22 78.3 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain FAS_meander PF17951.1 KKK19632.1 - 1.6e-17 63.7 0.0 3.1e-17 62.8 0.0 1.4 1 0 0 1 1 1 1 Fatty acid synthase meander beta sheet domain MaoC_dehydrat_N PF13452.6 KKK19632.1 - 7.8e-07 29.3 0.0 1.8e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase FAS_N PF17828.1 KKK19632.1 - 0.018 15.1 0.0 0.039 13.9 0.0 1.6 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta FAD_binding_3 PF01494.19 KKK19633.1 - 4.9e-13 49.0 7.0 1.7e-11 44.0 7.0 2.7 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KKK19633.1 - 0.0015 18.8 0.3 0.0038 17.4 0.3 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KKK19633.1 - 0.0035 17.0 0.9 0.0086 15.7 0.5 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase 3HCDH_N PF02737.18 KKK19633.1 - 0.044 13.7 0.2 0.073 12.9 0.2 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.27 KKK19633.1 - 0.048 14.2 1.0 0.21 12.2 0.2 2.5 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Glu_dehyd_C PF16912.5 KKK19633.1 - 0.11 12.0 0.0 0.62 9.5 0.0 2.2 3 0 0 3 3 3 0 Glucose dehydrogenase C-terminus F420_oxidored PF03807.17 KKK19633.1 - 0.14 12.7 0.4 0.37 11.4 0.4 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent SE PF08491.10 KKK19633.1 - 0.21 10.6 0.0 2.9 6.9 0.0 2.1 2 0 0 2 2 2 0 Squalene epoxidase Pyr_redox_2 PF07992.14 KKK19633.1 - 0.38 10.0 1.7 1.1 8.5 0.5 2.1 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 2OG-FeII_Oxy_2 PF13532.6 KKK19634.1 - 1.4e-13 51.5 0.0 1.7e-13 51.2 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 KKK19634.1 - 0.0039 17.7 0.0 0.0078 16.7 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily RrnaAD PF00398.20 KKK19635.1 - 8.2e-67 225.1 0.0 1.1e-66 224.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 KKK19635.1 - 4.7e-05 24.0 0.0 9e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KKK19635.1 - 0.0029 17.0 0.0 0.0044 16.4 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PCMT PF01135.19 KKK19635.1 - 0.0043 16.8 0.0 0.019 14.7 0.0 1.8 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_11 PF08241.12 KKK19635.1 - 0.0047 17.5 0.0 0.0099 16.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain AAA_lid_4 PF17864.1 KKK19635.1 - 0.014 15.1 0.0 0.034 13.9 0.0 1.6 1 0 0 1 1 1 0 RuvB AAA lid domain Methyltransf_23 PF13489.6 KKK19635.1 - 0.04 13.8 0.0 0.062 13.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 KKK19635.1 - 0.12 13.1 0.0 0.2 12.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Lipase_3 PF01764.25 KKK19637.1 - 1.2e-35 122.4 0.0 1.7e-35 121.9 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Lipase3_N PF03893.16 KKK19637.1 - 5e-08 32.9 0.3 1.2e-07 31.7 0.3 1.6 1 0 0 1 1 1 1 Lipase 3 N-terminal region FLgD_tudor PF13861.6 KKK19637.1 - 0.026 14.8 0.1 0.33 11.2 0.0 2.2 2 0 0 2 2 2 0 FlgD Tudor-like domain DUF2974 PF11187.8 KKK19637.1 - 0.032 13.8 0.8 0.57 9.7 0.8 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF2974) Hydrolase_4 PF12146.8 KKK19637.1 - 0.13 11.5 0.0 0.23 10.7 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Transferase PF02458.15 KKK19638.1 - 7.1e-07 28.2 0.0 0.00038 19.2 0.0 2.1 2 0 0 2 2 2 2 Transferase family AraC_binding PF02311.19 KKK19638.1 - 0.01 15.7 0.0 0.019 14.9 0.0 1.4 1 0 0 1 1 1 0 AraC-like ligand binding domain MFS_1 PF07690.16 KKK19639.1 - 1.3e-33 116.5 29.3 3.7e-33 114.9 29.3 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KKK19639.1 - 4.9e-18 65.2 5.6 7.5e-18 64.6 5.6 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 KKK19639.1 - 1.3e-15 56.9 9.9 1.6e-15 56.6 9.9 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF1726 PF08351.11 KKK19639.1 - 0.15 12.0 0.6 0.41 10.6 0.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1726) VKOR PF07884.14 KKK19639.1 - 9.1 6.5 14.7 2.4e+02 1.9 14.8 2.5 1 1 0 1 1 1 0 Vitamin K epoxide reductase family MFS_1 PF07690.16 KKK19640.1 - 1.9e-05 23.8 28.8 0.0001 21.3 19.2 2.4 2 1 1 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.13 KKK19640.1 - 0.005 15.3 3.0 0.0053 15.2 3.0 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.7 KKK19640.1 - 0.11 11.3 12.0 0.13 11.0 12.0 1.1 1 0 0 1 1 1 0 MFS_1 like family ketoacyl-synt PF00109.26 KKK19641.1 - 2.8e-68 230.3 0.0 5.8e-68 229.2 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 KKK19641.1 - 3.3e-29 101.3 0.0 1.3e-28 99.3 0.0 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain HTH_51 PF18558.1 KKK19641.1 - 5.1e-26 90.4 0.0 1.6e-25 88.8 0.0 2.0 2 0 0 2 2 1 1 Helix-turn-helix domain NAD_binding_4 PF07993.12 KKK19641.1 - 1.3e-25 90.1 0.0 2.1e-25 89.4 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Acyl_transf_1 PF00698.21 KKK19641.1 - 4.8e-22 78.9 0.0 2.6e-21 76.5 0.0 2.2 2 1 0 2 2 2 1 Acyl transferase domain PP-binding PF00550.25 KKK19641.1 - 5.3e-15 55.5 0.3 1.3e-14 54.3 0.3 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_12 PF08242.12 KKK19641.1 - 1.8e-13 51.1 0.0 6.4e-13 49.3 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain SAT PF16073.5 KKK19641.1 - 6.9e-10 39.1 0.3 4.8e-06 26.5 0.0 3.4 3 0 0 3 3 3 2 Starter unit:ACP transacylase in aflatoxin biosynthesis Methyltransf_25 PF13649.6 KKK19641.1 - 1.3e-09 38.7 0.0 8.2e-09 36.1 0.0 2.5 2 0 0 2 2 1 1 Methyltransferase domain Epimerase PF01370.21 KKK19641.1 - 3.4e-09 36.5 0.0 8.9e-09 35.1 0.0 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Methyltransf_11 PF08241.12 KKK19641.1 - 4.6e-07 30.4 0.0 7.7e-06 26.5 0.0 3.0 3 0 0 3 3 2 1 Methyltransferase domain PS-DH PF14765.6 KKK19641.1 - 6.4e-06 25.6 0.0 5.9e-05 22.5 0.0 2.3 2 0 0 2 2 2 1 Polyketide synthase dehydratase Methyltransf_31 PF13847.6 KKK19641.1 - 4.5e-05 23.3 0.0 0.00014 21.7 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KKK19641.1 - 0.0001 22.2 0.0 0.00031 20.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 KKK19641.1 - 0.0048 17.4 0.0 0.011 16.1 0.0 1.6 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Thiolase_N PF00108.23 KKK19641.1 - 0.0057 16.0 0.4 0.014 14.8 0.1 1.7 2 0 0 2 2 2 1 Thiolase, N-terminal domain Ubie_methyltran PF01209.18 KKK19641.1 - 0.016 14.6 0.0 0.032 13.6 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family ACP_syn_III PF08545.10 KKK19641.1 - 0.027 14.3 0.7 0.074 12.9 0.7 1.7 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 3Beta_HSD PF01073.19 KKK19641.1 - 0.22 10.5 0.2 19 4.2 0.0 2.5 3 0 0 3 3 3 0 3-beta hydroxysteroid dehydrogenase/isomerase family Fungal_trans PF04082.18 KKK19643.1 - 3.7e-16 58.9 0.2 5.7e-16 58.3 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Cellulase PF00150.18 KKK19644.1 - 2.6e-19 69.7 0.4 3.3e-19 69.4 0.4 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_C PF02836.17 KKK19644.1 - 0.0016 17.6 0.0 0.0031 16.7 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_42 PF02449.15 KKK19644.1 - 0.0023 17.3 0.1 0.015 14.7 0.1 1.9 2 0 0 2 2 2 1 Beta-galactosidase Sugar_tr PF00083.24 KKK19645.1 - 2e-137 458.8 22.8 2.3e-137 458.6 22.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKK19645.1 - 1.7e-20 73.3 46.3 4.7e-18 65.2 24.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KKK19645.1 - 0.2 10.2 25.8 0.017 13.7 0.9 2.9 3 1 0 3 3 3 0 MFS/sugar transport protein GST_C_3 PF14497.6 KKK19646.1 - 8.2e-09 35.6 0.0 1.4e-08 34.9 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KKK19646.1 - 9.2e-09 35.4 0.0 1.3e-08 34.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KKK19646.1 - 4.9e-07 29.7 0.1 8.4e-07 28.9 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glyco_tranf_2_3 PF13641.6 KKK19647.1 - 9.8e-18 64.9 0.0 1.6e-17 64.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 KKK19647.1 - 1.8e-05 24.3 0.0 4e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 KKK19647.1 - 0.00044 20.1 0.0 0.00074 19.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Response_reg PF00072.24 KKK19673.1 - 1.3e-20 73.6 0.0 1.7e-20 73.3 0.0 1.1 1 0 0 1 1 1 1 Response regulator receiver domain Sugar_tr PF00083.24 KKK19675.1 - 1.1e-89 301.3 24.5 1.4e-89 301.0 24.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKK19675.1 - 2.2e-27 95.9 20.7 3e-27 95.5 17.8 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KKK19675.1 - 4.6e-05 22.0 4.2 4.6e-05 22.0 4.2 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) PARG_cat PF05028.14 KKK19676.1 - 2.8e-44 151.8 0.0 3.8e-44 151.4 0.0 1.1 1 0 0 1 1 1 1 Poly (ADP-ribose) glycohydrolase (PARG) Trp_oprn_chp PF09534.10 KKK19677.1 - 0.25 11.1 3.1 4.3 7.1 0.2 2.1 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) NmrA PF05368.13 KKK19679.1 - 1.3e-38 132.9 0.0 1.6e-38 132.5 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KKK19679.1 - 3.6e-23 82.4 0.0 4.9e-23 82.0 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KKK19679.1 - 4.1e-05 23.2 0.0 0.00018 21.0 0.0 2.0 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KKK19679.1 - 0.02 13.9 0.0 0.052 12.5 0.0 1.6 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 KKK19679.1 - 0.023 14.2 0.0 0.041 13.3 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase TrkA_N PF02254.18 KKK19679.1 - 0.1 12.8 0.0 0.19 12.0 0.0 1.5 1 1 0 1 1 1 0 TrkA-N domain SHR3_chaperone PF08229.11 KKK19680.1 - 2.8e-74 248.2 0.0 3.2e-74 248.0 0.0 1.0 1 0 0 1 1 1 1 ER membrane protein SH3 DUF5453 PF17534.2 KKK19680.1 - 0.066 13.2 0.2 0.13 12.2 0.0 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5453) DUF202 PF02656.15 KKK19680.1 - 2.4 8.6 5.1 3.9 8.0 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF202) Zip PF02535.22 KKK19681.1 - 2.8e-37 128.7 10.7 2.8e-37 128.7 10.7 2.0 2 0 0 2 2 2 1 ZIP Zinc transporter Thyroglobulin_1 PF00086.18 KKK19681.1 - 0.016 14.9 0.4 6.9 6.4 0.1 2.4 2 0 0 2 2 2 0 Thyroglobulin type-1 repeat Acetyltransf_1 PF00583.25 KKK19682.1 - 5.7e-09 36.2 0.0 9.9e-09 35.5 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KKK19682.1 - 1.3e-08 35.1 0.0 1.8e-07 31.5 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KKK19682.1 - 3.9e-08 33.3 0.0 1.6e-07 31.3 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KKK19682.1 - 0.00021 21.4 0.0 0.014 15.5 0.0 2.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KKK19682.1 - 0.00032 20.6 0.0 0.00063 19.7 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 KKK19682.1 - 0.0013 18.8 0.0 0.0029 17.7 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase PanZ PF12568.8 KKK19682.1 - 0.0027 17.4 0.0 0.0072 16.1 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain, PanZ Hydrophobin PF01185.18 KKK19683.1 - 2.2e-08 34.6 7.2 3e-08 34.2 7.2 1.2 1 0 0 1 1 1 1 Fungal hydrophobin SRR1 PF07985.12 KKK19683.1 - 0.088 12.9 0.6 0.25 11.4 0.0 1.8 2 0 0 2 2 2 0 SRR1 bZIP_2 PF07716.15 KKK19684.1 - 6.5e-06 26.1 10.1 1.1e-05 25.4 10.1 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 KKK19684.1 - 8e-06 25.9 8.5 1.2e-05 25.3 8.5 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 KKK19684.1 - 0.0023 18.4 6.5 0.0039 17.7 6.5 1.2 1 0 0 1 1 1 1 bZIP Maf transcription factor MCC-bdg_PDZ PF10506.9 KKK19684.1 - 0.027 14.5 0.5 0.042 13.8 0.5 1.3 1 0 0 1 1 1 0 PDZ domain of MCC-2 bdg protein for Usher syndrome Macoilin PF09726.9 KKK19684.1 - 0.031 12.9 2.1 0.039 12.5 2.1 1.1 1 0 0 1 1 1 0 Macoilin family CASP_C PF08172.12 KKK19684.1 - 0.037 13.4 3.6 0.053 12.9 3.6 1.1 1 0 0 1 1 1 0 CASP C terminal DivIC PF04977.15 KKK19684.1 - 0.085 12.6 2.4 0.12 12.1 2.4 1.2 1 0 0 1 1 1 0 Septum formation initiator HALZ PF02183.18 KKK19684.1 - 0.089 13.0 0.7 0.15 12.3 0.7 1.4 1 0 0 1 1 1 0 Homeobox associated leucine zipper Nsp1_C PF05064.13 KKK19684.1 - 0.13 12.1 0.5 0.19 11.6 0.5 1.3 1 0 0 1 1 1 0 Nsp1-like C-terminal region Takusan PF04822.13 KKK19684.1 - 0.49 10.3 3.8 0.64 9.9 2.9 1.6 1 1 0 1 1 1 0 Takusan ATG16 PF08614.11 KKK19684.1 - 0.85 9.8 10.6 1.5 9.0 10.6 1.5 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) His_Phos_2 PF00328.22 KKK19686.1 - 1.9e-39 136.1 0.0 2.2e-39 135.9 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) AA_permease_2 PF13520.6 KKK19687.1 - 1.2e-55 189.1 42.1 1.6e-55 188.6 42.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KKK19687.1 - 2e-18 66.3 35.0 2.6e-18 65.9 35.0 1.0 1 0 0 1 1 1 1 Amino acid permease SLATT_fungal PF18142.1 KKK19687.1 - 4.3 7.4 6.1 1.3 9.1 1.0 2.3 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain p450 PF00067.22 KKK19690.1 - 1e-58 199.2 0.0 1.5e-58 198.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_10 PF00331.20 KKK19691.1 - 5e-99 331.4 1.4 3.1e-78 263.1 0.5 2.0 1 1 1 2 2 2 2 Glycosyl hydrolase family 10 GA-like PF17573.2 KKK19691.1 - 0.11 12.5 0.2 1 9.4 0.0 2.5 3 0 0 3 3 3 0 GA-like domain Arrestin_N PF00339.29 KKK19692.1 - 2.3e-13 50.4 0.0 7.8e-13 48.7 0.0 1.9 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 KKK19692.1 - 1.8e-09 38.2 0.0 1.2e-06 29.0 0.0 2.5 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain PWI PF01480.17 KKK19697.1 - 1.6e-16 60.4 1.0 3.6e-16 59.2 1.0 1.6 1 0 0 1 1 1 1 PWI domain DinB_2 PF12867.7 KKK19697.1 - 6.8 7.2 13.5 1.7e+03 -0.5 12.6 3.6 2 1 0 2 2 2 0 DinB superfamily MR_MLE_C PF13378.6 KKK19698.1 - 8.5e-58 195.5 0.0 1.2e-57 195.0 0.0 1.2 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 KKK19698.1 - 4e-07 30.2 0.0 8.2e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain PGI PF00342.19 KKK19700.1 - 3.2e-240 797.8 0.7 3.7e-240 797.6 0.7 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase Rhodanese PF00581.20 KKK19701.1 - 2.3e-10 41.0 0.0 2.9e-10 40.6 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain Cpn60_TCP1 PF00118.24 KKK19701.1 - 0.046 12.3 0.0 0.052 12.2 0.0 1.0 1 0 0 1 1 1 0 TCP-1/cpn60 chaperonin family Peptidase_C50 PF03568.17 KKK19701.1 - 0.11 11.6 0.0 0.12 11.5 0.0 1.1 1 0 0 1 1 1 0 Peptidase family C50 Ribosomal_S21 PF01165.20 KKK19702.1 - 1.9e-10 40.3 1.3 2.9e-10 39.7 1.3 1.3 1 0 0 1 1 1 1 Ribosomal protein S21 ArfGap PF01412.18 KKK19703.1 - 5.1e-33 113.6 0.7 8.3e-33 112.9 0.7 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf TIM21 PF08294.11 KKK19704.1 - 5.7e-42 143.0 0.0 7.2e-42 142.7 0.0 1.1 1 0 0 1 1 1 1 TIM21 Coa1 PF08695.10 KKK19704.1 - 8.8e-05 22.2 0.0 0.00018 21.2 0.0 1.5 1 1 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 Asp4 PF16996.5 KKK19704.1 - 0.14 11.9 0.1 0.27 11.1 0.1 1.4 1 0 0 1 1 1 0 Accessory secretory protein Sec Asp4 SAP30_Sin3_bdg PF13867.6 KKK19705.1 - 1.1e-08 35.2 0.1 1.2e-07 31.9 0.0 2.4 2 0 0 2 2 2 1 Sin3 binding region of histone deacetylase complex subunit SAP30 DUF410 PF04190.13 KKK19705.1 - 0.091 12.6 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF410) CNDH2_M PF16869.5 KKK19705.1 - 9 7.0 9.4 0.61 10.8 2.0 2.2 2 1 0 2 2 2 0 PF16858 LTV PF04180.14 KKK19708.1 - 4e-124 415.2 8.7 4.6e-124 415.1 8.7 1.0 1 0 0 1 1 1 1 Low temperature viability protein Pex26 PF07163.12 KKK19708.1 - 0.03 13.7 0.0 0.042 13.1 0.0 1.2 1 0 0 1 1 1 0 Pex26 protein DGF-1_C PF11040.8 KKK19708.1 - 0.32 11.0 8.1 0.2 11.7 1.2 3.3 3 1 0 3 3 3 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus Acyl-CoA_dh_1 PF00441.24 KKK19709.1 - 4.2e-28 98.5 1.2 7e-28 97.7 1.2 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KKK19709.1 - 2.1e-19 69.5 0.0 3.6e-19 68.8 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Spo12 PF05032.12 KKK19709.1 - 1.3e-15 56.9 1.4 3.1e-15 55.8 1.4 1.7 1 0 0 1 1 1 1 Spo12 family Acyl-CoA_dh_N PF02771.16 KKK19709.1 - 2.4e-12 47.5 0.0 5.6e-12 46.3 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 KKK19709.1 - 8.7e-12 45.5 2.6 1.4e-11 44.8 2.6 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain FAM110_C PF14160.6 KKK19709.1 - 0.022 15.8 0.7 0.043 14.9 0.7 1.4 1 0 0 1 1 1 0 Centrosome-associated C terminus MMR_HSR1 PF01926.23 KKK19710.1 - 7.9e-16 58.2 0.1 4.7e-14 52.4 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KKK19710.1 - 8.8e-08 31.8 0.2 2.1e-05 24.1 0.0 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KKK19710.1 - 2.2e-05 24.4 0.0 0.0079 16.1 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase Dynamin_N PF00350.23 KKK19710.1 - 0.0028 17.7 5.3 0.16 12.0 0.4 3.5 3 1 0 3 3 3 2 Dynamin family AIG1 PF04548.16 KKK19710.1 - 0.009 15.4 0.0 0.019 14.3 0.0 1.5 1 0 0 1 1 1 1 AIG1 family cobW PF02492.19 KKK19710.1 - 0.18 11.4 0.5 1.2 8.7 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Pkinase PF00069.25 KKK19711.1 - 1.4e-54 185.3 0.0 1.9e-54 184.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK19711.1 - 1.8e-31 109.4 0.0 2.4e-31 108.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KKK19711.1 - 1.2e-09 37.9 0.0 9.5e-07 28.4 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 KKK19711.1 - 0.023 14.1 0.0 0.039 13.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Sad1_UNC PF07738.13 KKK19712.1 - 1.7e-30 105.7 0.0 3.2e-30 104.8 0.0 1.5 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal CEP63 PF17045.5 KKK19712.1 - 0.24 11.2 6.6 0.44 10.4 6.6 1.3 1 0 0 1 1 1 0 Centrosomal protein of 63 kDa Zn_clus PF00172.18 KKK19723.1 - 1.1e-10 41.4 8.5 2.3e-10 40.4 8.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KKK19723.1 - 5.8e-09 35.4 0.0 9.6e-09 34.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans_2 PF11951.8 KKK19723.1 - 0.038 12.8 0.0 0.95 8.2 0.0 2.4 2 0 0 2 2 2 0 Fungal specific transcription factor domain DUF3455 PF11937.8 KKK19724.1 - 7.5e-17 62.2 0.0 1e-16 61.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) Cation_efflux PF01545.21 KKK19725.1 - 6.9e-23 81.4 13.0 8.7e-23 81.1 13.0 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 KKK19725.1 - 2.3e-06 27.6 0.0 4.6e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter Homeodomain PF00046.29 KKK19726.1 - 6.2e-15 54.8 3.3 1.3e-14 53.7 3.3 1.6 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KKK19726.1 - 0.13 12.2 0.4 0.3 11.0 0.4 1.6 1 0 0 1 1 1 0 Homeobox KN domain PhyH PF05721.13 KKK19727.1 - 1.6e-18 67.8 0.0 2.4e-18 67.2 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Sugar_tr PF00083.24 KKK19728.1 - 3.4e-100 336.1 25.5 3.8e-100 335.9 25.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKK19728.1 - 2.8e-31 108.8 48.6 7e-27 94.3 25.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KKK19728.1 - 0.00055 18.5 1.0 0.00097 17.7 1.0 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF3180 PF11377.8 KKK19728.1 - 0.15 12.2 5.0 0.46 10.6 1.1 2.8 1 1 0 2 2 2 0 Protein of unknown function (DUF3180) DUF1776 PF08643.10 KKK19735.1 - 2.5e-108 361.9 0.0 3.1e-108 361.7 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) adh_short PF00106.25 KKK19735.1 - 0.00016 21.2 0.0 0.00045 19.7 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase WLM PF08325.10 KKK19736.1 - 1.4e-68 230.8 0.0 2e-68 230.3 0.0 1.2 1 0 0 1 1 1 1 WLM domain zf-RanBP PF00641.18 KKK19736.1 - 8.8e-05 21.7 21.3 0.00046 19.4 5.0 3.4 3 0 0 3 3 3 3 Zn-finger in Ran binding protein and others DUF45 PF01863.17 KKK19736.1 - 0.0028 17.8 2.4 0.0059 16.7 2.4 1.5 1 0 0 1 1 1 1 Protein of unknown function DUF45 SprT-like PF10263.9 KKK19736.1 - 0.097 12.5 0.9 0.23 11.3 0.9 1.5 1 0 0 1 1 1 0 SprT-like family DZR PF12773.7 KKK19736.1 - 0.35 10.9 12.0 3.1 7.9 1.3 2.3 1 1 2 3 3 3 0 Double zinc ribbon SVIP PF15811.5 KKK19736.1 - 2.1 8.9 8.9 3.8 8.0 0.8 2.6 2 0 0 2 2 2 0 Small VCP/p97-interacting protein HypA PF01155.19 KKK19736.1 - 4.3 7.4 5.0 2.2 8.3 0.2 2.3 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Mito_carr PF00153.27 KKK19738.1 - 4.4e-47 157.9 3.3 3.2e-16 59.0 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein WD40 PF00400.32 KKK19739.1 - 1.6e-37 126.8 18.9 3.4e-05 24.5 0.0 7.6 8 0 0 8 8 8 6 WD domain, G-beta repeat F-box-like PF12937.7 KKK19739.1 - 3.2e-10 39.7 0.4 6.9e-10 38.7 0.4 1.5 1 0 0 1 1 1 1 F-box-like ANAPC4_WD40 PF12894.7 KKK19739.1 - 1.4e-07 31.7 0.6 0.33 11.3 0.0 4.9 1 1 5 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KKK19739.1 - 1.5e-05 23.9 6.4 0.027 13.1 0.1 4.8 3 1 3 6 6 6 2 Nucleoporin Nup120/160 WD40_like PF17005.5 KKK19739.1 - 9.4e-05 21.9 0.0 0.089 12.1 0.0 2.6 1 1 1 2 2 2 2 WD40-like domain F-box PF00646.33 KKK19739.1 - 0.00046 20.0 0.2 0.0011 18.8 0.2 1.7 1 0 0 1 1 1 1 F-box domain PALB2_WD40 PF16756.5 KKK19739.1 - 0.0099 14.8 2.7 14 4.5 0.0 3.9 3 1 0 4 4 4 1 Partner and localizer of BRCA2 WD40 domain PQQ_2 PF13360.6 KKK19739.1 - 0.026 14.1 5.3 0.022 14.4 1.8 2.5 1 1 1 2 2 2 0 PQQ-like domain PQQ_3 PF13570.6 KKK19739.1 - 0.12 12.9 5.9 23 5.6 0.1 4.7 3 1 1 4 4 4 0 PQQ-like domain F-box_5 PF18511.1 KKK19739.1 - 0.12 12.0 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 F-box DUF5046 PF16465.5 KKK19739.1 - 0.15 11.5 0.0 6 6.2 0.0 2.6 1 1 1 3 3 3 0 Domain of unknown function (DUF5046) Lipase_GDSL_2 PF13472.6 KKK19740.1 - 1.2e-18 68.1 0.3 1.9e-18 67.5 0.3 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KKK19740.1 - 4.9e-08 33.2 0.1 1.4e-07 31.7 0.1 1.8 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase OSK PF17182.4 KKK19740.1 - 0.00029 20.1 0.1 0.00062 19.1 0.1 1.4 1 1 0 1 1 1 1 OSK domain 2-ph_phosp PF04029.14 KKK19740.1 - 0.12 11.5 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 2-phosphosulpholactate phosphatase CENP-T_C PF15511.6 KKK19741.1 - 4.4e-09 36.4 0.1 5.3e-09 36.2 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 KKK19741.1 - 1.9e-05 25.1 0.2 2.2e-05 24.8 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.17 KKK19741.1 - 5e-05 23.4 0.2 7.3e-05 22.9 0.2 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 KKK19741.1 - 0.00012 22.3 0.1 0.00021 21.5 0.1 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 KKK19741.1 - 0.00017 21.9 0.1 0.00023 21.5 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 KKK19741.1 - 0.0038 17.3 0.0 0.0045 17.0 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 KKK19741.1 - 0.0045 17.0 0.0 0.0054 16.7 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated UPF0137 PF03677.13 KKK19741.1 - 0.05 13.4 0.2 0.061 13.1 0.2 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) TFIID_20kDa PF03847.13 KKK19741.1 - 0.059 13.9 0.0 0.12 12.9 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A HIGH_NTase1_ass PF16581.5 KKK19741.1 - 0.073 13.1 0.0 0.082 12.9 0.0 1.1 1 0 0 1 1 1 0 Cytidyltransferase-related C-terminal region Mito_carr PF00153.27 KKK19742.1 - 1.3e-37 127.6 8.1 1.5e-14 53.6 0.0 4.2 4 0 0 4 4 4 3 Mitochondrial carrier protein SH3_9 PF14604.6 KKK19742.1 - 0.00023 21.0 0.1 0.0011 18.8 0.2 2.1 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 KKK19742.1 - 0.001 18.6 0.2 0.0021 17.6 0.2 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KKK19742.1 - 0.0062 16.2 0.3 0.021 14.5 0.1 2.0 2 0 0 2 2 2 1 Variant SH3 domain DUF883 PF05957.13 KKK19742.1 - 0.37 11.4 4.6 0.17 12.5 0.3 2.7 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Annexin PF00191.20 KKK19743.1 - 1.9e-59 197.6 2.3 1.1e-17 63.8 0.0 4.1 4 0 0 4 4 4 4 Annexin DUF5617 PF18493.1 KKK19743.1 - 0.15 12.2 0.1 0.5 10.5 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5617) Acetyltransf_11 PF13720.6 KKK19743.1 - 0.63 10.5 2.1 52 4.4 0.1 3.6 4 0 0 4 4 4 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 CBM_21 PF03370.13 KKK19744.1 - 9.4e-35 119.2 2.9 1.5e-34 118.5 2.9 1.3 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 KKK19744.1 - 1.1e-10 41.9 5.4 2.1e-10 41.1 5.4 1.4 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) Zn_clus PF00172.18 KKK19745.1 - 1.1e-10 41.5 11.8 2.5e-10 40.3 11.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ATG27 PF09451.10 KKK19745.1 - 0.24 11.2 1.5 0.37 10.6 1.5 1.2 1 0 0 1 1 1 0 Autophagy-related protein 27 adh_short PF00106.25 KKK19746.1 - 3.2e-34 118.1 0.1 4.4e-34 117.7 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KKK19746.1 - 2.4e-25 89.5 0.0 3.5e-25 88.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KKK19746.1 - 4.3e-08 33.3 2.3 8.6e-07 29.0 2.4 2.5 1 1 1 2 2 2 1 KR domain UPF0146 PF03686.13 KKK19746.1 - 0.018 14.9 0.0 0.034 14.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0146) Epimerase PF01370.21 KKK19746.1 - 0.035 13.5 0.0 0.057 12.9 0.0 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family B12-binding PF02310.19 KKK19746.1 - 0.11 12.6 0.1 2.5 8.1 0.0 2.6 3 0 0 3 3 3 0 B12 binding domain Zn_clus PF00172.18 KKK19747.1 - 4.3e-10 39.6 9.7 4.3e-10 39.6 9.7 1.9 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3439 PF11921.8 KKK19747.1 - 0.1 12.6 11.1 0.22 11.5 11.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Opy2 PF09463.10 KKK19747.1 - 1 9.7 11.5 0.16 12.3 3.5 2.9 3 0 0 3 3 3 0 Opy2 protein Pyr_redox_3 PF13738.6 KKK19748.1 - 3.9e-13 49.3 0.0 1.1e-12 47.8 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KKK19748.1 - 9e-13 47.5 0.0 1.6e-09 36.8 0.0 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 KKK19748.1 - 1.6e-09 37.4 0.0 1.7e-08 34.0 0.0 2.3 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 KKK19748.1 - 2e-08 33.8 0.0 1.1e-06 28.2 0.0 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KKK19748.1 - 3.7e-05 23.8 0.2 0.0094 15.9 0.1 2.8 2 1 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KKK19748.1 - 0.00017 21.8 0.0 0.00043 20.4 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KKK19748.1 - 0.00032 20.0 0.2 0.00068 18.9 0.0 1.6 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.27 KKK19748.1 - 0.0012 19.4 0.5 0.72 10.4 0.0 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KKK19748.1 - 0.071 11.8 0.0 9.2 4.8 0.0 2.2 2 0 0 2 2 2 0 HI0933-like protein STE PF02200.16 KKK19749.1 - 1.4e-56 189.6 0.1 2.3e-56 188.9 0.1 1.3 1 0 0 1 1 1 1 STE like transcription factor zf-C2H2 PF00096.26 KKK19749.1 - 2.3e-11 43.5 9.8 1e-06 28.8 0.5 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KKK19749.1 - 6e-09 35.9 4.1 6e-09 35.9 4.1 3.2 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KKK19749.1 - 6.5e-08 32.8 7.8 0.00078 20.1 0.3 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KKK19749.1 - 0.00067 19.6 3.9 0.0011 18.9 0.1 2.4 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KKK19749.1 - 0.013 15.7 0.1 0.23 11.8 0.0 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zinc_ribbon_9 PF14369.6 KKK19749.1 - 0.088 13.1 0.2 0.22 11.8 0.2 1.7 1 0 0 1 1 1 0 zinc-ribbon zf-TRAF PF02176.18 KKK19749.1 - 0.16 12.7 2.6 0.28 11.9 2.6 1.4 1 0 0 1 1 1 0 TRAF-type zinc finger NOA36 PF06524.12 KKK19749.1 - 0.23 10.7 0.1 0.37 10.1 0.1 1.2 1 0 0 1 1 1 0 NOA36 protein zf-Di19 PF05605.12 KKK19749.1 - 0.48 10.7 3.5 1.3 9.3 3.5 1.8 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2HC_2 PF13913.6 KKK19749.1 - 1.2 9.1 5.5 1.5 8.8 0.3 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-H2C2_5 PF13909.6 KKK19749.1 - 5.4 6.9 9.6 27 4.6 3.0 3.2 3 0 0 3 3 3 0 C2H2-type zinc-finger domain MFS_2 PF13347.6 KKK19750.1 - 1.6e-08 33.6 5.2 1.6e-08 33.6 5.2 2.3 2 0 0 2 2 2 2 MFS/sugar transport protein DUF2417 PF10329.9 KKK19750.1 - 4.1 6.8 6.6 2.9 7.2 0.4 2.9 3 0 0 3 3 3 0 Region of unknown function (DUF2417) Na_H_Exchanger PF00999.21 KKK19751.1 - 1.1e-68 231.7 39.7 1.4e-68 231.4 39.7 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF4396 PF14342.6 KKK19751.1 - 1 9.8 8.4 6.8 7.0 2.5 3.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4396) TPR_21 PF09976.9 KKK19752.1 - 0.1 12.3 0.1 0.2 11.4 0.1 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat-like domain APH PF01636.23 KKK19753.1 - 8.6e-13 48.8 0.0 1.5e-12 47.9 0.0 1.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KKK19753.1 - 0.00013 21.7 0.0 0.00024 20.8 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 KKK19753.1 - 0.0018 17.9 0.1 0.034 13.8 0.0 2.1 2 0 0 2 2 2 1 RIO1 family ADH_N PF08240.12 KKK19754.1 - 3.7e-28 97.6 0.1 8.2e-28 96.5 0.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KKK19754.1 - 1.7e-15 57.2 0.3 3.1e-15 56.3 0.3 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KKK19754.1 - 0.0021 19.1 0.0 0.0034 18.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 KKK19754.1 - 0.012 14.9 0.2 0.023 14.1 0.2 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 KKK19754.1 - 0.026 13.8 0.7 0.043 13.1 0.7 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain SNF2_N PF00176.23 KKK19755.1 - 2.7e-64 217.1 1.6 2.7e-64 217.1 1.6 1.8 2 0 0 2 2 2 1 SNF2 family N-terminal domain DBINO PF13892.6 KKK19755.1 - 2e-48 164.1 20.7 2e-48 164.1 20.7 4.9 4 1 1 5 5 5 1 DNA-binding domain Helicase_C PF00271.31 KKK19755.1 - 2.3e-19 69.8 0.0 6.3e-19 68.4 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KKK19755.1 - 2.5e-06 27.6 0.0 2.5e-06 27.6 0.0 2.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KKK19755.1 - 0.00083 19.2 0.0 0.0028 17.4 0.0 2.0 1 0 0 1 1 1 1 DEAD/DEAH box helicase HDA2-3 PF11496.8 KKK19755.1 - 0.016 14.4 0.0 0.11 11.6 0.0 2.4 2 1 0 2 2 2 0 Class II histone deacetylase complex subunits 2 and 3 His_biosynth PF00977.21 KKK19756.1 - 8.7e-33 113.7 0.0 1.2e-32 113.3 0.0 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein DUF4602 PF15375.6 KKK19757.1 - 1.7e-11 44.6 32.8 3.8e-10 40.2 32.8 2.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4602) Nop25 PF09805.9 KKK19757.1 - 0.0053 17.2 11.3 0.0053 17.2 11.3 3.0 2 1 0 2 2 2 1 Nucleolar protein 12 (25kDa) PI3K_1B_p101 PF10486.9 KKK19757.1 - 1.4 6.6 10.8 1.8 6.2 10.8 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit NOA36 PF06524.12 KKK19757.1 - 9.9 5.4 20.4 2.1 7.6 15.5 2.2 2 0 0 2 2 2 0 NOA36 protein Aminotran_1_2 PF00155.21 KKK19758.1 - 1.1e-73 248.5 0.1 1e-54 186.1 0.1 2.2 1 1 1 2 2 2 2 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KKK19758.1 - 2e-05 23.3 0.0 3.5e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 KKK19758.1 - 7.6e-05 22.2 0.2 0.00014 21.3 0.2 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 KKK19758.1 - 0.00067 18.7 0.0 0.0011 18.0 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KKK19758.1 - 0.044 13.1 0.3 0.14 11.5 0.2 1.6 1 1 0 1 1 1 0 Beta-eliminating lyase AA_permease_2 PF13520.6 KKK19759.1 - 2.6e-67 227.5 48.3 3.1e-67 227.3 48.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KKK19759.1 - 1e-11 44.1 39.3 1.4e-11 43.7 39.3 1.1 1 0 0 1 1 1 1 Amino acid permease Acetyltransf_13 PF13880.6 KKK19759.1 - 0.043 13.8 0.1 0.68 9.9 0.0 2.5 2 0 0 2 2 2 0 ESCO1/2 acetyl-transferase zf-C2H2_jaz PF12171.8 KKK19763.1 - 0.0051 17.1 8.1 0.16 12.3 0.4 3.5 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KKK19763.1 - 5.8 7.4 7.6 0.34 11.4 0.2 2.9 3 0 0 3 3 3 0 Zinc-finger of C2H2 type DAO PF01266.24 KKK19765.1 - 1e-24 87.8 0.1 1.3e-24 87.5 0.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase TrkA_N PF02254.18 KKK19765.1 - 0.0008 19.7 0.0 0.04 14.2 0.0 2.3 2 0 0 2 2 2 1 TrkA-N domain Thi4 PF01946.17 KKK19765.1 - 0.013 14.8 0.1 0.2 10.9 0.1 2.1 2 0 0 2 2 2 0 Thi4 family Pyr_redox PF00070.27 KKK19765.1 - 0.021 15.4 0.3 0.094 13.3 0.1 2.1 2 1 1 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KKK19765.1 - 0.072 13.3 0.1 0.13 12.5 0.1 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Sacchrp_dh_NADP PF03435.18 KKK19765.1 - 0.16 12.2 0.1 0.79 10.0 0.1 2.1 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain CytochromB561_N PF09786.9 KKK19766.1 - 0.38 9.7 8.3 0.5 9.3 8.3 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal PAP1 PF08601.10 KKK19766.1 - 1.7 8.3 15.4 2.3 7.9 15.4 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 Podoplanin PF05808.11 KKK19767.1 - 0.002 18.3 0.0 0.0027 17.8 0.0 1.2 1 0 0 1 1 1 1 Podoplanin DUF4690 PF15756.5 KKK19767.1 - 0.015 15.9 0.2 0.035 14.7 0.2 1.6 1 0 0 1 1 1 0 Small Novel Rich in Cartilage Fibrinogen_C PF00147.18 KKK19767.1 - 0.053 13.3 0.0 0.075 12.8 0.0 1.3 1 0 0 1 1 1 0 Fibrinogen beta and gamma chains, C-terminal globular domain Pkinase PF00069.25 KKK19768.1 - 1.9e-35 122.5 0.0 2.8e-20 72.8 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KKK19768.1 - 1.4e-18 67.1 0.0 1.3e-09 37.8 0.0 2.6 2 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KKK19768.1 - 0.024 14.0 0.1 0.37 10.0 0.0 2.6 3 0 0 3 3 3 0 Kinase-like FTA2 PF13095.6 KKK19768.1 - 0.04 13.5 0.0 5.1 6.7 0.0 2.4 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 OFCC1 PF15680.5 KKK19768.1 - 0.067 13.8 1.6 0.11 13.0 0.3 1.9 2 0 0 2 2 2 0 Orofacial cleft 1 candidate gene 1 protein FXa_inhibition PF14670.6 KKK19768.1 - 0.076 13.3 0.4 0.16 12.3 0.4 1.5 1 0 0 1 1 1 0 Coagulation Factor Xa inhibitory site Kdo PF06293.14 KKK19768.1 - 0.14 11.5 0.8 0.23 10.8 0.1 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Syja_N PF02383.18 KKK19769.1 - 2.1e-79 267.1 0.0 3.8e-79 266.3 0.0 1.4 1 0 0 1 1 1 1 SacI homology domain Tti2 PF10521.9 KKK19770.1 - 7.9e-95 317.6 0.6 1.2e-94 317.0 0.6 1.3 1 0 0 1 1 1 1 Tti2 family PolyA_pol PF01743.20 KKK19771.1 - 4.9e-24 85.2 0.2 1.1e-23 84.0 0.2 1.7 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 KKK19771.1 - 5.2e-07 29.3 0.0 1.2e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A tRNA_NucTran2_2 PF13735.6 KKK19771.1 - 0.0022 18.0 0.1 0.0055 16.7 0.1 1.6 1 0 0 1 1 1 1 tRNA nucleotidyltransferase domain 2 putative TetR_C_31 PF17940.1 KKK19771.1 - 0.0081 16.3 0.2 0.023 14.9 0.2 1.8 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TRAPPC-Trs85 PF12739.7 KKK19772.1 - 4.6e-109 365.1 0.0 6.9e-109 364.5 0.0 1.2 1 0 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit Abhydrolase_4 PF08386.10 KKK19773.1 - 1.9e-18 66.4 0.0 5.8e-18 64.9 0.0 1.8 2 0 0 2 2 2 1 TAP-like protein Abhydrolase_1 PF00561.20 KKK19773.1 - 1.3e-16 61.0 0.0 8.2e-16 58.4 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold NAD_binding_4 PF07993.12 KKK19773.1 - 0.14 11.3 0.0 0.29 10.3 0.0 1.4 1 0 0 1 1 1 0 Male sterility protein CytadhesinP1 PF12378.8 KKK19774.1 - 0.081 13.1 0.1 0.085 13.0 0.1 1.1 1 0 0 1 1 1 0 Trypsin-sensitive surface-exposed protein DNA_pol_B PF00136.21 KKK19775.1 - 2.1e-147 491.6 2.7 2.9e-147 491.1 2.7 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 KKK19775.1 - 7.5e-83 278.4 0.1 1.6e-82 277.3 0.1 1.6 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 KKK19775.1 - 1.7e-18 66.8 5.6 3.6e-18 65.8 5.6 1.6 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta RNase_H_2 PF13482.6 KKK19775.1 - 0.0014 18.6 0.3 0.01 15.9 0.3 2.3 1 1 0 1 1 1 1 RNase_H superfamily DNA_pol_B_exo2 PF10108.9 KKK19775.1 - 0.096 12.3 0.1 0.2 11.3 0.1 1.5 1 0 0 1 1 1 0 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB Fer2_BFD PF04324.15 KKK19775.1 - 6.2 7.3 7.1 18 5.8 0.2 3.3 1 1 2 3 3 3 0 BFD-like [2Fe-2S] binding domain STIMATE PF12400.8 KKK19783.1 - 3e-40 137.6 5.4 4.6e-40 137.1 4.4 1.8 2 0 0 2 2 2 1 STIMATE family RRM_1 PF00076.22 KKK19783.1 - 1.3e-18 66.5 0.4 2.1e-18 65.9 0.4 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KKK19783.1 - 4.9e-05 22.9 0.0 9.3e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KKK19783.1 - 0.016 15.0 0.0 0.028 14.3 0.0 1.3 1 0 0 1 1 1 0 Occluded RNA-recognition motif DUF4271 PF14093.6 KKK19783.1 - 0.21 11.5 5.5 0.52 10.2 5.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4271) PRIMA1 PF16101.5 KKK19783.1 - 1.4 8.9 3.7 1.4 9.0 1.3 2.1 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 Pam16 PF03656.13 KKK19784.1 - 3.8e-35 120.7 0.5 4.7e-35 120.4 0.5 1.0 1 0 0 1 1 1 1 Pam16 PAP_assoc PF03828.19 KKK19785.1 - 1.8e-15 56.9 0.3 3.7e-15 55.9 0.3 1.6 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 KKK19785.1 - 9.4e-11 41.9 0.0 4e-10 39.8 0.0 2.0 2 0 0 2 2 2 1 Nucleotidyltransferase domain Mito_fiss_reg PF05308.11 KKK19785.1 - 0.073 13.1 16.8 0.1 12.6 9.3 2.3 2 0 0 2 2 2 0 Mitochondrial fission regulator Pex24p PF06398.11 KKK19786.1 - 3.6e-100 335.5 0.7 5.1e-100 335.0 0.7 1.2 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Fungal_trans_2 PF11951.8 KKK19787.1 - 1.3e-19 70.3 0.3 1.5e-19 70.1 0.3 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain ADH_N PF08240.12 KKK19788.1 - 1.1e-20 73.5 0.8 1.8e-20 72.8 0.8 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KKK19788.1 - 1.1e-16 61.0 0.1 2.1e-16 60.1 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_7 PF13241.6 KKK19788.1 - 0.00068 20.0 0.0 0.0014 19.0 0.0 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding Glu_dehyd_C PF16912.5 KKK19788.1 - 0.0014 18.2 0.1 0.0024 17.4 0.1 1.4 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus DAO PF01266.24 KKK19788.1 - 0.017 14.7 0.2 0.025 14.1 0.2 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KKK19788.1 - 0.023 14.0 0.2 0.033 13.5 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain ADH_zinc_N_2 PF13602.6 KKK19788.1 - 0.066 14.3 0.0 0.15 13.1 0.0 1.6 1 1 0 1 1 1 0 Zinc-binding dehydrogenase Thiolase_C PF02803.18 KKK19789.1 - 3e-11 43.0 0.5 8.6e-11 41.6 0.6 1.8 1 1 0 1 1 1 1 Thiolase, C-terminal domain Thiolase_N PF00108.23 KKK19789.1 - 3.5e-08 33.1 0.1 0.0057 16.0 0.2 2.8 2 1 0 2 2 2 2 Thiolase, N-terminal domain BRO1 PF03097.18 KKK19790.1 - 5.8e-126 420.4 0.5 1.2e-125 419.3 0.0 1.8 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 KKK19790.1 - 1e-69 235.1 19.2 1.2e-35 123.3 11.6 2.7 1 1 1 2 2 2 2 ALIX V-shaped domain binding to HIV Mito_carr PF00153.27 KKK19790.1 - 3.5e-39 132.6 3.9 1.6e-14 53.6 0.1 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein MSA-2c PF12238.8 KKK19790.1 - 0.062 13.3 1.6 0.17 11.8 1.6 1.8 1 0 0 1 1 1 0 Merozoite surface antigen 2c RRM_1 PF00076.22 KKK19791.1 - 2.6e-13 49.6 0.0 5.2e-13 48.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KKK19791.1 - 0.023 14.7 0.1 0.074 13.1 0.1 1.8 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif SMN PF06003.12 KKK19792.1 - 3.5e-06 26.5 6.2 0.00053 19.3 1.8 2.3 1 1 1 2 2 2 2 Survival motor neuron protein (SMN) PH PF00169.29 KKK19825.1 - 3.7e-07 30.6 0.2 1.2e-06 29.0 0.2 1.9 1 0 0 1 1 1 1 PH domain DUF3921 PF13060.6 KKK19825.1 - 0.049 13.7 0.2 0.13 12.3 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3921) ApoO PF09769.9 KKK19825.1 - 0.54 10.2 2.2 16 5.5 0.1 3.4 4 0 0 4 4 4 0 Apolipoprotein O RRM_1 PF00076.22 KKK19826.1 - 1.5e-45 152.8 0.0 4e-17 61.8 0.0 3.8 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KKK19826.1 - 3.5e-05 23.4 0.0 0.0066 16.1 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 KKK19826.1 - 0.00018 21.5 0.5 2.4 8.3 0.0 4.4 3 2 0 3 3 3 1 Limkain b1 PknH_C PF14032.6 KKK19826.1 - 0.012 15.5 3.6 12 5.6 0.2 3.2 3 0 0 3 3 3 0 PknH-like extracellular domain ATP-grasp_2 PF08442.10 KKK19826.1 - 0.015 14.9 0.0 0.12 12.0 0.0 2.2 2 0 0 2 2 2 0 ATP-grasp domain RRM_Rrp7 PF17799.1 KKK19826.1 - 0.015 15.1 0.0 7.9 6.3 0.0 2.9 3 0 0 3 3 3 0 Rrp7 RRM-like N-terminal domain RRM_3 PF08777.11 KKK19826.1 - 0.05 13.7 0.0 6.9 6.8 0.0 3.0 3 0 0 3 3 3 0 RNA binding motif RRM_occluded PF16842.5 KKK19826.1 - 0.055 13.3 0.0 15 5.5 0.0 3.1 2 1 0 2 2 2 0 Occluded RNA-recognition motif Phage_TAC_13 PF16459.5 KKK19826.1 - 0.074 13.5 0.1 89 3.6 0.0 3.2 3 0 0 3 3 3 0 Phage tail assembly chaperone, TAC COQ9 PF08511.11 KKK19827.1 - 5.7e-28 96.5 0.1 1.1e-27 95.6 0.1 1.5 1 0 0 1 1 1 1 COQ9 PPR_2 PF13041.6 KKK19828.1 - 0.23 11.7 0.0 0.57 10.4 0.0 1.7 1 0 0 1 1 1 0 PPR repeat family K_channel_TID PF07941.11 KKK19828.1 - 0.56 10.7 7.8 8.4 6.9 1.1 2.9 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain WD40 PF00400.32 KKK19829.1 - 1.3e-05 25.9 0.3 0.96 10.4 0.0 3.8 3 0 0 3 3 3 2 WD domain, G-beta repeat DUF4799 PF16056.5 KKK19829.1 - 0.011 14.9 0.7 0.017 14.3 0.2 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4799) Palm_thioest PF02089.15 KKK19830.1 - 4.1e-84 282.2 0.0 4.8e-84 282.0 0.0 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF915 PF06028.11 KKK19830.1 - 0.0069 15.7 0.0 0.012 14.9 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_1 PF00561.20 KKK19830.1 - 0.023 14.4 0.0 0.044 13.4 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Med31 PF05669.12 KKK19832.1 - 1.7e-31 108.1 0.0 2.1e-31 107.7 0.0 1.1 1 0 0 1 1 1 1 SOH1 Alk_phosphatase PF00245.20 KKK19833.1 - 4.9e-61 206.9 0.1 1.8e-60 205.1 0.1 1.8 1 1 0 1 1 1 1 Alkaline phosphatase Sulfatase PF00884.23 KKK19833.1 - 1.3e-06 28.1 0.5 4.4e-06 26.3 0.5 2.0 2 1 0 2 2 2 1 Sulfatase Phosphodiest PF01663.22 KKK19833.1 - 5.5e-05 22.9 0.1 0.0001 22.0 0.1 1.5 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 KKK19833.1 - 0.0026 16.4 0.1 0.0046 15.6 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF229) HHH_3 PF12836.7 KKK19833.1 - 0.018 15.3 0.0 0.04 14.2 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix motif Metalloenzyme PF01676.18 KKK19833.1 - 0.029 13.7 0.0 0.053 12.9 0.0 1.4 1 0 0 1 1 1 0 Metalloenzyme superfamily Terpene_synth_C PF03936.16 KKK19851.1 - 0.0081 15.5 0.2 0.011 15.1 0.2 1.3 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain p450 PF00067.22 KKK19852.1 - 1.2e-50 172.6 0.0 1.8e-50 172.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 KKK19853.1 - 4.6e-39 134.3 51.2 4.6e-39 134.3 51.2 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KKK19853.1 - 0.004 16.1 44.4 0.0029 16.5 38.3 3.2 1 1 0 2 2 2 1 Sugar (and other) transporter Sugar_tr PF00083.24 KKK19854.1 - 1.2e-114 383.6 23.9 1.4e-114 383.4 23.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKK19854.1 - 1.1e-22 80.5 24.8 1.1e-22 80.5 24.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4131 PF13567.6 KKK19854.1 - 2.6 7.7 7.2 6.1 6.5 0.5 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Abhydrolase_2 PF02230.16 KKK19855.1 - 7.7e-26 91.2 0.0 9.8e-19 68.0 0.0 2.1 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 KKK19855.1 - 0.055 12.7 0.0 1.6 8.0 0.0 2.4 2 1 0 2 2 2 0 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KKK19855.1 - 0.1 12.1 0.0 0.9 9.0 0.0 2.2 3 0 0 3 3 3 0 Prolyl oligopeptidase family AA_permease PF00324.21 KKK19856.1 - 1.9e-118 396.1 46.3 2.2e-118 395.9 46.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KKK19856.1 - 2e-40 139.0 49.0 3.3e-40 138.2 49.0 1.3 1 0 0 1 1 1 1 Amino acid permease HtrL_YibB PF09612.10 KKK19857.1 - 0.05 13.1 0.2 0.068 12.7 0.2 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (HtrL_YibB) EB PF01683.18 KKK19857.1 - 1.4 9.3 22.6 16 5.9 6.6 2.4 1 1 1 2 2 2 0 EB module Dickkopf_N PF04706.12 KKK19857.1 - 9.5 6.8 20.1 11 6.6 16.9 2.3 1 1 1 2 2 2 0 Dickkopf N-terminal cysteine-rich region p450 PF00067.22 KKK19858.1 - 7.6e-71 239.2 0.0 8.8e-71 239.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF1910 PF08928.10 KKK19860.1 - 0.13 12.2 0.1 0.28 11.2 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1910) MFS_1 PF07690.16 KKK19861.1 - 2.2e-09 36.7 16.5 1.2e-06 27.7 7.0 3.7 3 1 1 4 4 4 2 Major Facilitator Superfamily TRI12 PF06609.13 KKK19861.1 - 3e-05 22.6 1.0 3e-05 22.6 1.0 2.6 2 1 1 3 3 3 2 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KKK19861.1 - 0.0002 20.3 2.3 0.0002 20.3 2.3 2.7 3 1 0 3 3 3 1 Sugar (and other) transporter Glyco_hydro_75 PF07335.11 KKK19862.1 - 4.1e-41 141.0 0.1 7.7e-41 140.1 0.1 1.5 1 0 0 1 1 1 1 Fungal chitosanase of glycosyl hydrolase group 75 Glyco_hydro_61 PF03443.14 KKK19862.1 - 0.018 15.0 0.1 0.032 14.2 0.1 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 61 EB PF01683.18 KKK19862.1 - 2.7 8.3 28.7 1.2 9.4 9.0 3.1 2 1 1 3 3 3 0 EB module Malic_M PF03949.15 KKK19863.1 - 1.1e-89 300.1 0.0 1.6e-89 299.6 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 KKK19863.1 - 5.1e-64 215.4 0.2 1.2e-63 214.2 0.0 1.7 2 0 0 2 2 2 1 Malic enzyme, N-terminal domain Glyco_hydro_61 PF03443.14 KKK19864.1 - 0.056 13.4 0.0 0.16 11.9 0.0 1.7 1 1 0 1 1 1 0 Glycosyl hydrolase family 61 MFS_1 PF07690.16 KKK19865.1 - 4.2e-40 137.8 33.3 4.2e-40 137.8 33.3 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KKK19865.1 - 3.5e-14 52.5 5.6 3.5e-14 52.5 5.6 1.7 2 0 0 2 2 2 1 Sugar (and other) transporter Zn_clus PF00172.18 KKK19865.1 - 4e-06 26.8 10.6 8.7e-06 25.8 10.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain E1-E2_ATPase PF00122.20 KKK19866.1 - 1.8e-39 135.2 1.5 6.6e-39 133.3 0.9 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 KKK19866.1 - 8.3e-37 126.7 3.0 8.3e-37 126.7 3.0 2.6 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KKK19866.1 - 8.1e-23 81.8 0.1 1.8e-10 41.4 0.0 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KKK19866.1 - 4.9e-17 61.8 0.0 9.1e-17 60.9 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KKK19866.1 - 2.2e-09 36.9 0.0 5.4e-09 35.6 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus DUF2157 PF09925.9 KKK19866.1 - 1.4e-05 24.9 7.4 0.00036 20.4 0.1 3.4 4 0 0 4 4 4 2 Predicted membrane protein (DUF2157) Hydrolase_3 PF08282.12 KKK19866.1 - 4.1e-05 23.4 0.2 7.9e-05 22.5 0.2 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Sigma_reg_N PF13800.6 KKK19866.1 - 0.08 13.2 1.1 0.38 11.1 1.1 2.1 1 0 0 1 1 1 0 Sigma factor regulator N-terminal TMEM43 PF07787.12 KKK19866.1 - 0.12 11.8 1.4 3.5 6.9 0.3 2.4 2 0 0 2 2 2 0 Transmembrane protein 43 DUF3262 PF11660.8 KKK19866.1 - 0.45 10.9 6.5 9.6 6.7 0.1 3.1 3 0 0 3 3 2 0 Protein of unknown function (DUF3262) DUF2207 PF09972.9 KKK19866.1 - 1.1 8.0 2.7 19 3.8 0.0 2.6 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) DUF1218 PF06749.12 KKK19866.1 - 5.4 7.6 7.5 0.66 10.5 0.2 3.0 3 0 0 3 3 2 0 Protein of unknown function (DUF1218) SnoaL_2 PF12680.7 KKK19867.1 - 3.2e-06 27.7 0.2 3.9e-06 27.4 0.2 1.1 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_4 PF13577.6 KKK19867.1 - 2.3e-05 24.5 0.2 3e-05 24.1 0.2 1.2 1 0 0 1 1 1 1 SnoaL-like domain ZipA_C PF04354.13 KKK19867.1 - 0.12 12.3 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 ZipA, C-terminal FtsZ-binding domain MFS_1 PF07690.16 KKK19868.1 - 6.5e-06 25.3 1.5 0.00019 20.5 2.4 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KKK19868.1 - 0.0085 14.6 0.8 0.0098 14.4 0.8 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 KKK19868.1 - 0.019 13.3 0.2 0.057 11.7 0.1 1.6 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Pam17 PF08566.10 KKK19868.1 - 0.065 13.1 0.6 0.16 11.8 0.3 1.7 1 1 1 2 2 2 0 Mitochondrial import protein Pam17 MFS_1 PF07690.16 KKK19869.1 - 8.4e-06 24.9 27.0 2.9e-05 23.2 27.0 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Cytomega_TRL10 PF06084.11 KKK19869.1 - 0.019 15.0 1.8 0.15 12.1 0.2 2.4 2 0 0 2 2 2 0 Cytomegalovirus TRL10 protein Pox_A14 PF05767.12 KKK19869.1 - 6.9 6.9 7.3 0.52 10.5 0.3 2.6 4 0 0 4 4 4 0 Poxvirus virion envelope protein A14 Esterase PF00756.20 KKK19870.1 - 7.7e-10 38.8 0.0 2.3e-09 37.3 0.0 1.8 1 1 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.8 KKK19870.1 - 0.00018 20.9 0.0 0.00023 20.5 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KKK19870.1 - 0.00044 20.9 0.1 0.00055 20.6 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KKK19870.1 - 0.0018 17.8 0.0 0.003 17.1 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family DEAD PF00270.29 KKK19871.1 - 5.5e-48 163.1 0.0 1.2e-47 161.9 0.0 1.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KKK19871.1 - 1.7e-31 108.8 0.0 4.4e-31 107.5 0.0 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KKK19871.1 - 0.0046 17.0 0.0 0.0083 16.1 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 KKK19871.1 - 0.11 11.8 0.1 0.19 11.1 0.1 1.2 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit ERCC3_RAD25_C PF16203.5 KKK19871.1 - 0.11 11.7 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase Adeno_PIX PF03955.14 KKK19872.1 - 1.9 8.7 10.2 4.5 7.5 10.2 1.5 1 0 0 1 1 1 0 Adenovirus hexon-associated protein (IX) TAF4 PF05236.14 KKK19872.1 - 2 8.1 14.2 2.9 7.6 11.7 2.2 2 0 0 2 2 2 0 Transcription initiation factor TFIID component TAF4 family K_channel_TID PF07941.11 KKK19872.1 - 4.1 7.9 16.9 15 6.1 16.9 2.0 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain RskA PF10099.9 KKK19872.1 - 7.7 6.8 16.7 0.73 10.1 11.3 2.1 3 0 0 3 3 3 0 Anti-sigma-K factor rskA INSIG PF07281.12 KKK19873.1 - 9.1e-77 257.5 0.9 1.2e-76 257.1 0.9 1.2 1 0 0 1 1 1 1 Insulin-induced protein (INSIG) NLE PF08154.12 KKK19874.1 - 4e-19 68.9 0.1 1.3e-18 67.2 0.1 2.0 1 0 0 1 1 1 1 NLE (NUC135) domain WD40 PF00400.32 KKK19874.1 - 4.6e-13 49.4 19.3 0.0064 17.3 0.1 6.6 6 0 0 6 6 6 5 WD domain, G-beta repeat Zw10 PF06248.13 KKK19874.1 - 1.2e-11 43.9 0.9 2.3e-11 43.0 0.9 1.4 1 0 0 1 1 1 1 Centromere/kinetochore Zw10 Dsl1_C PF11989.8 KKK19874.1 - 6e-08 32.6 0.2 1.4e-07 31.4 0.2 1.6 1 0 0 1 1 1 1 Retrograde transport protein Dsl1 C terminal TMF_TATA_bd PF12325.8 KKK19874.1 - 0.55 10.5 3.0 1.2 9.4 1.4 2.5 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Seryl_tRNA_N PF02403.22 KKK19874.1 - 0.83 9.9 5.1 0.25 11.6 1.0 2.3 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Ribosomal_S13 PF00416.22 KKK19875.1 - 9.6e-18 64.8 0.3 1.4e-13 51.3 2.1 2.0 1 1 1 2 2 2 2 Ribosomal protein S13/S18 Pro_isomerase PF00160.21 KKK19876.1 - 6.4e-48 163.0 0.2 8.5e-48 162.6 0.2 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Bromodomain PF00439.25 KKK19877.1 - 1.7e-25 88.9 0.2 3.4e-25 87.9 0.2 1.5 1 0 0 1 1 1 1 Bromodomain Acetyltransf_1 PF00583.25 KKK19877.1 - 2.2e-07 31.1 0.0 4.1e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KKK19877.1 - 3.3e-07 30.3 0.1 7.3e-07 29.2 0.1 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KKK19877.1 - 0.00053 20.4 0.3 0.0011 19.4 0.1 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Peptidase_M16_C PF05193.21 KKK19878.1 - 3.7e-17 62.9 0.0 5.1e-15 56.0 0.0 2.9 3 0 0 3 3 3 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 KKK19878.1 - 3.3e-06 27.2 0.0 1.2e-05 25.3 0.0 2.0 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) DNA_pol_phi PF04931.13 KKK19878.1 - 0.0024 16.1 27.4 0.0042 15.3 27.4 1.4 1 0 0 1 1 1 1 DNA polymerase phi TFIIA PF03153.13 KKK19878.1 - 0.19 11.7 19.8 0.37 10.8 19.8 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit M16C_assoc PF08367.11 KKK19878.1 - 0.66 9.1 6.0 19 4.3 4.4 2.5 2 0 0 2 2 2 0 Peptidase M16C associated DUF4600 PF15372.6 KKK19878.1 - 2.8 8.4 5.8 1.3 9.5 0.1 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4600) SSrecog PF03531.14 KKK19879.1 - 2.9e-30 104.0 1.7 2.9e-29 100.8 0.0 3.4 5 0 0 5 5 5 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.12 KKK19879.1 - 4.5e-27 94.3 0.0 4.9e-26 91.0 0.0 2.2 2 0 0 2 2 2 1 Histone chaperone Rttp106-like CDC45 PF02724.14 KKK19879.1 - 5.6 5.1 12.4 9 4.4 12.4 1.4 1 0 0 1 1 1 0 CDC45-like protein Asp PF00026.23 KKK19880.1 - 9.7e-29 100.8 0.3 1.3e-28 100.4 0.3 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KKK19880.1 - 0.00026 21.3 4.4 0.0017 18.6 2.5 2.7 1 1 1 2 2 2 1 Xylanase inhibitor N-terminal FA_desaturase PF00487.24 KKK19881.1 - 1.3e-26 94.0 30.7 1.9e-26 93.5 30.7 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 KKK19881.1 - 5e-10 39.4 0.0 1.1e-09 38.3 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Pro_isomerase PF00160.21 KKK19882.1 - 1.1e-42 146.0 0.0 1.8e-42 145.3 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD U-box PF04564.15 KKK19882.1 - 0.00058 20.0 0.6 0.0071 16.5 0.0 2.8 2 1 0 3 3 3 1 U-box domain Rtf2 PF04641.12 KKK19882.1 - 0.0016 17.8 0.5 0.016 14.6 0.0 2.5 2 1 0 2 2 2 1 Rtf2 RING-finger zf-NOSIP PF15906.5 KKK19882.1 - 0.0049 17.0 0.0 0.011 15.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein GTP_EFTU PF00009.27 KKK19883.1 - 3.7e-59 199.6 0.0 5.9e-59 198.9 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 KKK19883.1 - 6.3e-09 36.1 0.0 2e-08 34.5 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 KKK19883.1 - 2.4e-07 30.8 0.0 5.4e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.18 KKK19883.1 - 0.0063 16.3 0.0 0.027 14.2 0.0 2.1 1 1 0 1 1 1 1 Elongation factor G, domain IV MMR_HSR1 PF01926.23 KKK19883.1 - 0.061 13.4 0.0 0.18 11.9 0.0 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase RhoGAP-FF1 PF16512.5 KKK19883.1 - 0.25 12.1 1.8 2 9.2 0.0 2.8 3 0 0 3 3 3 0 p190-A and -B Rho GAPs FF domain DUF4604 PF15377.6 KKK19884.1 - 9.7e-24 84.7 16.3 1.1e-23 84.5 16.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) Prp19 PF08606.11 KKK19885.1 - 3.5e-33 113.4 2.8 5.8e-33 112.7 2.8 1.4 1 0 0 1 1 1 1 Prp19/Pso4-like ANAPC4_WD40 PF12894.7 KKK19885.1 - 3.4e-16 59.3 0.6 4.1e-07 30.2 0.0 4.7 3 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KKK19885.1 - 5.2e-12 46.1 0.5 0.00017 22.3 0.0 5.4 5 0 0 5 5 5 2 WD domain, G-beta repeat Coatomer_WDAD PF04053.14 KKK19885.1 - 3e-08 33.2 0.2 2.7e-05 23.4 0.0 2.2 1 1 1 2 2 2 2 Coatomer WD associated region eIF2A PF08662.11 KKK19885.1 - 3.9e-05 23.6 0.1 0.016 15.1 0.0 2.8 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A U-box PF04564.15 KKK19885.1 - 0.00056 20.0 0.0 0.0011 19.0 0.0 1.5 1 0 0 1 1 1 1 U-box domain WD40_like PF17005.5 KKK19885.1 - 0.0017 17.8 0.0 0.0066 15.8 0.0 1.9 1 1 0 1 1 1 1 WD40-like domain PQQ_2 PF13360.6 KKK19885.1 - 0.0039 16.8 5.8 0.075 12.6 1.4 2.5 1 1 1 2 2 2 2 PQQ-like domain V_ATPase_I_N PF18670.1 KKK19885.1 - 0.0091 16.4 0.2 0.021 15.2 0.2 1.5 1 0 0 1 1 1 1 V-type ATPase subunit I, N-terminal domain PQQ PF01011.21 KKK19885.1 - 0.089 12.8 0.0 0.28 11.2 0.0 2.0 1 0 0 1 1 1 0 PQQ enzyme repeat Frtz PF11768.8 KKK19885.1 - 0.24 9.6 0.0 0.69 8.2 0.0 1.6 1 1 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz L51_S25_CI-B8 PF05047.16 KKK19886.1 - 5.2e-15 55.1 0.1 8.7e-15 54.4 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain U1snRNP70_N PF12220.8 KKK19887.1 - 1.6e-25 89.5 4.1 1.6e-25 89.5 4.1 1.7 2 0 0 2 2 2 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.22 KKK19887.1 - 6.5e-12 45.1 0.0 1.2e-11 44.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KKK19887.1 - 9.6e-05 22.4 0.0 0.00017 21.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif AAA PF00004.29 KKK19888.1 - 2.7e-07 31.1 0.1 0.00084 19.8 0.0 2.4 1 1 1 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KKK19888.1 - 8e-06 26.3 0.0 1.5e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain TIP49 PF06068.13 KKK19888.1 - 0.08 12.1 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain F-box-like PF12937.7 KKK19889.1 - 0.00013 21.8 0.3 0.00031 20.6 0.3 1.7 1 0 0 1 1 1 1 F-box-like PalH PF08733.10 KKK19890.1 - 2e-111 372.2 0.0 2.4e-111 371.9 0.0 1.1 1 0 0 1 1 1 1 PalH/RIM21 Asp PF00026.23 KKK19892.1 - 6.8e-70 236.0 5.8 9.5e-70 235.5 5.8 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KKK19892.1 - 1.7e-09 38.2 1.5 5.4e-05 23.5 0.1 3.3 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KKK19892.1 - 1.2e-06 29.1 0.6 0.09 13.4 0.0 3.1 2 1 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 KKK19892.1 - 0.0038 17.8 0.7 2.6 8.7 0.0 3.1 2 1 0 2 2 2 2 gag-polyprotein putative aspartyl protease TAXi_C PF14541.6 KKK19892.1 - 0.0095 15.7 0.0 0.023 14.5 0.0 1.8 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal Triabin PF03973.13 KKK19892.1 - 0.039 13.8 0.1 0.11 12.4 0.1 1.7 1 1 1 2 2 2 0 Triabin PPC PF04151.15 KKK19892.1 - 1.7 9.8 10.6 4.7 8.4 2.6 3.0 2 1 0 2 2 2 0 Bacterial pre-peptidase C-terminal domain PLAC8 PF04749.17 KKK19893.1 - 9.6e-20 71.4 16.6 1.3e-19 71.0 16.6 1.2 1 0 0 1 1 1 1 PLAC8 family Peptidase_C13 PF01650.18 KKK19894.1 - 0.0032 17.0 0.0 0.006 16.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase C13 family APOBEC_N PF08210.11 KKK19894.1 - 0.16 11.8 0.0 0.38 10.6 0.0 1.5 1 0 0 1 1 1 0 APOBEC-like N-terminal domain ERCC4 PF02732.15 KKK19895.1 - 2.6e-35 122.0 0.0 9.2e-35 120.2 0.0 2.0 2 0 0 2 2 2 1 ERCC4 domain Glycos_transf_1 PF00534.20 KKK19895.1 - 1.6e-31 109.2 0.4 7.3e-30 103.8 0.4 2.3 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KKK19895.1 - 7.7e-15 55.3 0.0 1.8e-06 28.1 0.0 2.8 2 0 0 2 2 2 2 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 KKK19895.1 - 1.1e-12 48.6 0.0 2.6e-12 47.3 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 KKK19895.1 - 5e-06 27.0 0.4 0.09 13.2 0.3 2.9 3 0 0 3 3 3 2 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 KKK19895.1 - 0.0059 17.0 0.0 0.02 15.3 0.0 1.9 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_hydr_30_2 PF14587.6 KKK19895.1 - 0.045 13.3 0.0 0.14 11.7 0.1 1.7 2 0 0 2 2 2 0 O-Glycosyl hydrolase family 30 MAS20 PF02064.15 KKK19895.1 - 8.5 6.5 10.1 14 5.8 0.1 2.7 2 0 0 2 2 2 0 MAS20 protein import receptor Mhr1 PF12829.7 KKK19896.1 - 7e-30 103.0 0.5 1.2e-29 102.2 0.5 1.4 1 0 0 1 1 1 1 Transcriptional regulation of mitochondrial recombination DUF5480 PF17576.2 KKK19896.1 - 0.14 12.2 0.0 0.27 11.3 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5480) IPK PF03770.16 KKK19897.1 - 9.7e-61 205.1 0.0 1.7e-60 204.3 0.0 1.4 1 0 0 1 1 1 1 Inositol polyphosphate kinase Pam17 PF08566.10 KKK19897.1 - 0.067 13.0 0.1 0.13 12.1 0.1 1.4 1 0 0 1 1 1 0 Mitochondrial import protein Pam17 MFS_1 PF07690.16 KKK19898.1 - 8.9e-19 67.6 11.8 8.9e-19 67.6 11.8 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily Nodulin-like PF06813.13 KKK19898.1 - 3.6e-09 36.5 1.5 8.4e-09 35.3 1.5 1.6 1 0 0 1 1 1 1 Nodulin-like DUF3784 PF12650.7 KKK19898.1 - 4.4 7.6 0.0 4.4 7.6 0.0 5.3 5 1 1 6 6 6 0 Domain of unknown function (DUF3784) Atg14 PF10186.9 KKK19899.1 - 6.4e-17 61.6 14.9 1.7e-15 56.9 0.1 2.3 2 0 0 2 2 2 2 Vacuolar sorting 38 and autophagy-related subunit 14 VPS38 PF17649.1 KKK19899.1 - 2.1e-09 36.8 0.7 0.011 14.6 0.0 3.1 3 0 0 3 3 3 3 Vacuolar protein sorting 38 APG6 PF04111.12 KKK19899.1 - 0.021 14.8 0.0 0.042 13.8 0.0 1.5 1 0 0 1 1 1 0 Apg6 BARA domain YjeF_N PF03853.15 KKK19900.1 - 1.5e-39 135.6 0.1 2.2e-39 135.1 0.1 1.2 1 0 0 1 1 1 1 YjeF-related protein N-terminus FDF PF09532.10 KKK19900.1 - 3.6e-08 34.2 1.0 6.9e-08 33.3 1.0 1.4 1 0 0 1 1 1 1 FDF domain PP2C PF00481.21 KKK19901.1 - 5.9e-62 209.6 0.1 3.4e-50 171.1 0.2 3.1 2 1 0 2 2 2 2 Protein phosphatase 2C TIM PF00121.18 KKK19903.1 - 2.3e-90 302.2 0.5 2.6e-90 302.1 0.5 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase DeoRC PF00455.22 KKK19903.1 - 0.0019 18.1 0.6 0.76 9.7 0.3 3.0 1 1 2 3 3 3 2 DeoR C terminal sensor domain CutC PF03932.14 KKK19903.1 - 0.043 13.3 0.1 0.071 12.6 0.1 1.4 1 0 0 1 1 1 0 CutC family START PF01852.19 KKK19903.1 - 0.075 12.4 0.1 0.11 12.0 0.1 1.2 1 0 0 1 1 1 0 START domain Dynamin_N PF00350.23 KKK19904.1 - 4.8e-17 62.5 0.0 1e-16 61.4 0.0 1.6 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 KKK19904.1 - 1.8e-10 40.9 0.0 1.4e-09 38.1 0.0 2.5 2 1 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KKK19904.1 - 4.2e-06 26.4 0.3 0.00016 21.3 0.5 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain DUF2205 PF10224.9 KKK19904.1 - 0.016 15.2 0.1 0.052 13.5 0.1 1.9 1 0 0 1 1 1 0 Short coiled-coil protein AAA_18 PF13238.6 KKK19904.1 - 0.02 15.4 0.0 0.15 12.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 KKK19904.1 - 0.069 13.2 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE IIGP PF05049.13 KKK19904.1 - 0.079 12.0 0.0 0.16 11.0 0.0 1.4 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) Snf7 PF03357.21 KKK19905.1 - 1.3e-34 119.3 15.6 5.2e-34 117.3 15.9 1.6 2 0 0 2 2 2 1 Snf7 Remorin_C PF03763.13 KKK19905.1 - 1 9.3 6.9 0.99 9.3 5.5 1.8 1 1 0 1 1 1 0 Remorin, C-terminal region YlqD PF11068.8 KKK19905.1 - 1.5 9.2 17.0 2.5 8.5 6.7 2.1 1 1 1 2 2 2 0 YlqD protein Zn_clus PF00172.18 KKK19906.1 - 4.8e-08 33.0 8.7 4.8e-08 33.0 8.7 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MIT PF04212.18 KKK19906.1 - 0.015 15.3 0.0 0.048 13.7 0.0 1.9 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain zf-RING_14 PF17978.1 KKK19906.1 - 0.27 11.7 2.8 0.63 10.5 2.8 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain PTCB-BRCT PF12738.7 KKK19907.1 - 8.4e-23 80.1 1.3 3.4e-10 39.7 0.0 4.3 5 0 0 5 5 5 2 twin BRCT domain BRCT PF00533.26 KKK19907.1 - 1.2e-17 64.1 0.6 9.9e-07 29.1 0.0 4.6 5 1 0 5 5 5 2 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 KKK19907.1 - 2.2e-10 40.8 0.0 0.48 10.9 0.0 4.8 5 0 0 5 5 5 4 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 KKK19907.1 - 0.00045 20.5 2.4 0.49 10.7 0.1 3.7 4 0 0 4 4 4 2 DNA ligase 3 BRCT domain PIF1 PF05970.14 KKK19908.1 - 3.9e-64 217.1 0.0 1.9e-49 168.8 0.0 2.1 1 1 1 2 2 2 2 PIF1-like helicase AAA_30 PF13604.6 KKK19908.1 - 7.2e-24 84.6 0.0 1.4e-23 83.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KKK19908.1 - 2.8e-12 47.2 0.0 5.5e-12 46.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KKK19908.1 - 1e-06 29.1 0.0 4.4e-06 27.0 0.0 2.1 2 0 0 2 2 1 1 AAA domain AAA_7 PF12775.7 KKK19908.1 - 1.7e-05 24.4 0.0 3.4e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region UvrD_C_2 PF13538.6 KKK19908.1 - 0.00012 21.9 0.1 0.00069 19.4 0.1 2.4 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_16 PF13191.6 KKK19908.1 - 0.00013 22.4 0.0 0.00036 21.0 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain Herpes_Helicase PF02689.14 KKK19908.1 - 0.0003 18.9 0.1 0.0014 16.7 0.0 1.9 2 0 0 2 2 2 1 Helicase T2SSE PF00437.20 KKK19908.1 - 0.0014 17.7 0.0 0.0027 16.8 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein DUF2075 PF09848.9 KKK19908.1 - 0.002 17.4 0.2 0.033 13.4 0.0 2.5 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) RNA_helicase PF00910.22 KKK19908.1 - 0.0052 17.2 0.0 0.016 15.6 0.0 1.8 1 0 0 1 1 1 1 RNA helicase NB-ARC PF00931.22 KKK19908.1 - 0.0052 16.0 0.0 0.0086 15.3 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA PF00004.29 KKK19908.1 - 0.0072 16.7 0.0 0.016 15.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 KKK19908.1 - 0.011 15.5 2.7 0.015 15.1 0.0 2.5 3 0 0 3 3 3 0 AAA domain ATPase_2 PF01637.18 KKK19908.1 - 0.012 15.5 0.3 0.037 13.9 0.3 1.8 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea UvrD-helicase PF00580.21 KKK19908.1 - 0.012 15.2 0.7 0.017 14.6 0.0 1.6 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain RsgA_GTPase PF03193.16 KKK19908.1 - 0.017 15.0 0.1 0.035 14.0 0.1 1.4 1 0 0 1 1 1 0 RsgA GTPase SH3_13 PF18335.1 KKK19908.1 - 0.019 14.8 0.0 0.055 13.3 0.0 1.8 1 0 0 1 1 1 0 ATP-dependent RecD-like DNA helicase SH3 domain Viral_helicase1 PF01443.18 KKK19908.1 - 0.022 14.5 0.2 11 5.6 0.1 3.0 3 1 0 3 3 2 0 Viral (Superfamily 1) RNA helicase PhoH PF02562.16 KKK19908.1 - 0.024 14.1 0.0 0.069 12.6 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein ResIII PF04851.15 KKK19908.1 - 0.026 14.6 0.0 0.06 13.3 0.0 1.8 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit TrwB_AAD_bind PF10412.9 KKK19908.1 - 0.029 13.3 0.0 0.053 12.4 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain NACHT PF05729.12 KKK19908.1 - 0.031 14.2 0.0 0.068 13.1 0.0 1.5 1 0 0 1 1 1 0 NACHT domain DUF5605 PF18310.1 KKK19908.1 - 0.051 13.5 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5605) AAA_14 PF13173.6 KKK19908.1 - 0.054 13.5 0.0 0.26 11.3 0.0 2.2 1 1 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 KKK19908.1 - 0.073 12.8 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain MMR_HSR1 PF01926.23 KKK19908.1 - 0.11 12.6 0.0 0.23 11.5 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_5 PF07728.14 KKK19908.1 - 0.11 12.4 0.3 1.5 8.8 0.3 2.5 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) RL10P_insert PF17777.1 KKK19909.1 - 1.2e-21 76.4 0.0 2e-21 75.7 0.0 1.4 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 KKK19909.1 - 5.7e-19 68.1 0.0 1.1e-18 67.1 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L10 MDM10 PF12519.8 KKK19911.1 - 2.6e-146 488.2 10.3 3e-124 415.4 8.8 2.0 1 1 1 2 2 2 2 Mitochondrial distribution and morphology protein 10 Porin_3 PF01459.22 KKK19911.1 - 0.027 13.9 0.1 2 7.8 0.0 3.0 3 0 0 3 3 3 0 Eukaryotic porin Acatn PF13000.7 KKK19911.1 - 0.18 10.3 0.6 0.25 9.8 0.6 1.1 1 0 0 1 1 1 0 Acetyl-coenzyme A transporter 1 Thioredoxin PF00085.20 KKK19912.1 - 2e-27 95.2 0.0 2.6e-27 94.8 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KKK19912.1 - 2.1e-07 31.3 0.1 5.2e-07 30.1 0.1 1.6 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KKK19912.1 - 3.6e-07 30.4 0.0 6.7e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 KKK19912.1 - 3.4e-05 23.8 0.0 4.7e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_9 PF14595.6 KKK19912.1 - 0.00018 21.3 0.0 0.00022 21.0 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 KKK19912.1 - 0.0003 20.2 0.0 0.00042 19.7 0.0 1.3 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Redoxin PF08534.10 KKK19912.1 - 0.00055 19.7 0.3 0.0057 16.4 0.1 2.0 1 1 1 2 2 2 1 Redoxin TraF PF13728.6 KKK19912.1 - 0.003 17.4 0.0 0.0044 16.9 0.0 1.2 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_7 PF13899.6 KKK19912.1 - 0.0093 16.1 0.1 0.022 14.9 0.1 1.7 1 1 0 1 1 1 1 Thioredoxin-like Phosducin PF02114.16 KKK19912.1 - 0.059 12.3 0.0 0.076 11.9 0.0 1.1 1 0 0 1 1 1 0 Phosducin Aldo_ket_red PF00248.21 KKK19913.1 - 6.4e-53 179.9 0.0 7.2e-53 179.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family adh_short_C2 PF13561.6 KKK19914.1 - 1.7e-50 171.8 0.7 1.9e-50 171.6 0.7 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KKK19914.1 - 9.1e-45 152.5 0.5 1.1e-44 152.2 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KKK19914.1 - 4e-10 39.9 0.3 5.8e-10 39.4 0.3 1.3 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KKK19914.1 - 0.00057 19.1 0.1 0.00072 18.8 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein ThiF PF00899.21 KKK19914.1 - 0.12 11.7 0.3 0.39 10.0 0.2 1.9 2 1 0 2 2 2 0 ThiF family Ank_2 PF12796.7 KKK19915.1 - 2.2e-54 182.0 0.0 1.7e-11 44.5 0.0 6.0 2 2 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KKK19915.1 - 1.3e-50 169.1 0.5 7.5e-09 36.0 0.0 8.2 4 2 4 8 8 8 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 KKK19915.1 - 6.9e-40 130.5 0.4 0.02 15.4 0.0 12.7 13 0 0 13 13 13 9 Ankyrin repeat Aa_trans PF01490.18 KKK19915.1 - 2.5e-39 135.1 31.6 3.5e-39 134.7 31.6 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Ank_5 PF13857.6 KKK19915.1 - 6.9e-37 125.0 0.3 3.2e-06 27.3 0.0 8.3 3 2 4 8 8 8 6 Ankyrin repeats (many copies) Ank PF00023.30 KKK19915.1 - 6.8e-30 102.2 0.1 0.24 11.9 0.0 12.0 12 0 0 12 12 12 8 Ankyrin repeat F-box-like PF12937.7 KKK19915.1 - 2.9e-06 27.1 0.1 1.2e-05 25.1 0.1 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KKK19915.1 - 0.00015 21.5 0.0 0.00033 20.5 0.0 1.6 1 0 0 1 1 1 1 F-box domain DUF2678 PF10856.8 KKK19915.1 - 0.037 14.0 2.6 0.19 11.6 0.1 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2678) Acetyltransf_3 PF13302.7 KKK19916.1 - 3.3e-14 53.7 0.0 5.5e-14 53.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KKK19916.1 - 4.2e-06 27.0 0.0 7.1e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 KKK19916.1 - 0.0011 19.2 0.0 0.0016 18.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain PG_binding_2 PF08823.11 KKK19916.1 - 0.16 12.3 1.5 0.63 10.4 0.7 2.2 2 0 0 2 2 2 0 Putative peptidoglycan binding domain NACHT PF05729.12 KKK19917.1 - 2.4e-10 40.6 0.1 6.5e-10 39.2 0.1 1.8 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KKK19917.1 - 4.2e-10 40.3 0.2 1.9e-09 38.2 0.1 2.2 2 0 0 2 2 2 1 AAA ATPase domain ATPase_2 PF01637.18 KKK19917.1 - 5.1e-07 29.8 0.2 3.8e-05 23.7 0.0 2.3 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_22 PF13401.6 KKK19917.1 - 0.0001 22.6 2.5 0.00099 19.4 0.1 3.2 3 1 1 4 4 4 1 AAA domain AAA PF00004.29 KKK19917.1 - 0.00055 20.4 0.0 0.002 18.6 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 KKK19917.1 - 0.00073 18.8 0.3 0.0022 17.3 0.0 1.9 2 0 0 2 2 2 1 NB-ARC domain APS_kinase PF01583.20 KKK19917.1 - 0.0015 18.5 0.1 0.0038 17.1 0.1 1.7 1 0 0 1 1 1 1 Adenylylsulphate kinase NACHT_N PF17100.5 KKK19917.1 - 0.0035 17.2 2.9 0.1 12.5 2.3 2.6 1 1 0 1 1 1 1 N-terminal domain of NWD NACHT-NTPase AAA_30 PF13604.6 KKK19917.1 - 0.036 13.8 0.0 0.075 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KKK19917.1 - 0.047 14.2 2.0 0.16 12.5 0.1 3.0 4 1 0 4 4 4 0 AAA domain Zeta_toxin PF06414.12 KKK19917.1 - 0.049 12.9 0.0 0.13 11.5 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin RNA_helicase PF00910.22 KKK19917.1 - 0.068 13.6 0.0 0.18 12.2 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_33 PF13671.6 KKK19917.1 - 0.16 12.2 0.4 1 9.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain Cytidylate_kin PF02224.18 KKK19917.1 - 0.16 11.7 0.0 0.61 9.8 0.0 1.9 2 0 0 2 2 2 0 Cytidylate kinase KAP_NTPase PF07693.14 KKK19917.1 - 0.48 9.6 7.4 4.2 6.5 7.3 2.7 1 1 0 1 1 1 0 KAP family P-loop domain Fib_alpha PF08702.10 KKK19917.1 - 0.74 10.0 4.9 15 5.8 1.7 2.8 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Fungal_trans PF04082.18 KKK19918.1 - 2e-08 33.6 0.4 3.2e-08 32.9 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK19918.1 - 8.8e-08 32.2 7.1 1.5e-07 31.4 7.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 KKK19919.1 - 1.2e-35 123.1 66.8 3.8e-25 88.5 33.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Pox_A9 PF04835.12 KKK19919.1 - 1.3 9.2 4.1 0.68 10.1 1.0 2.1 2 0 0 2 2 2 0 A9 protein conserved region MFS_1_like PF12832.7 KKK19919.1 - 9.9 4.9 32.2 2.7 6.7 7.7 3.3 3 1 0 3 3 3 0 MFS_1 like family Pyr_redox_2 PF07992.14 KKK19920.1 - 5.1e-32 111.3 0.0 7.5e-32 110.7 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KKK19920.1 - 1.2e-07 32.2 0.0 2.3e-05 24.9 0.0 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KKK19920.1 - 0.0072 15.6 0.0 1.1 8.5 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase SQHop_cyclase_N PF13249.6 KKK19921.1 - 1.2e-89 300.3 0.2 1.2e-82 277.3 0.0 3.4 3 1 0 3 3 3 3 Squalene-hopene cyclase N-terminal domain SQHop_cyclase_C PF13243.6 KKK19921.1 - 1.4e-85 287.2 2.2 2.1e-81 273.5 0.9 3.4 2 2 1 3 3 3 2 Squalene-hopene cyclase C-terminal domain Prenyltrans PF00432.21 KKK19921.1 - 3.3e-17 61.9 17.9 1.1e-05 25.0 0.1 6.2 6 0 0 6 6 6 4 Prenyltransferase and squalene oxidase repeat TED_complement PF07678.14 KKK19921.1 - 0.0005 19.2 0.1 1.8 7.5 0.0 3.9 4 1 1 5 5 5 2 A-macroglobulin TED domain Pec_lyase PF09492.10 KKK19921.1 - 0.09 12.1 0.0 5.1 6.3 0.0 2.7 2 1 0 2 2 2 0 Pectic acid lyase Transket_pyr PF02779.24 KKK19922.1 - 7.3e-42 143.0 0.2 1e-41 142.6 0.2 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KKK19922.1 - 1.1e-09 38.2 0.0 0.00073 19.4 0.0 2.6 1 1 1 2 2 2 2 Transketolase, C-terminal domain Arylsulfotran_2 PF14269.6 KKK19923.1 - 4.2e-58 197.1 0.3 5.9e-58 196.6 0.3 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 KKK19923.1 - 1.2e-16 60.7 2.3 3.3e-16 59.2 2.3 1.6 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) RCC1 PF00415.18 KKK19934.1 - 1.5e-38 131.2 9.5 9.1e-09 35.8 0.2 7.8 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KKK19934.1 - 3.6e-29 99.9 29.1 4.6e-09 35.9 0.5 7.7 8 0 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat SUKH-3 PF14433.6 KKK19934.1 - 0.083 13.4 0.1 27 5.2 0.0 3.4 3 0 0 3 3 3 0 SUKH-3 immunity protein Hira PF07569.11 KKK19934.1 - 0.15 11.8 0.0 5.6 6.6 0.0 3.3 4 0 0 4 4 4 0 TUP1-like enhancer of split DHDPS PF00701.22 KKK19949.1 - 9.9e-45 152.5 0.0 1.3e-44 152.1 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family SAS4 PF15460.6 KKK19950.1 - 6.3e-32 109.6 11.2 1.1e-31 108.8 11.2 1.4 1 0 0 1 1 1 1 Something about silencing, SAS, complex subunit 4 Clr5 PF14420.6 KKK19951.1 - 7.5e-18 64.5 2.3 1.2e-17 63.8 2.3 1.4 1 0 0 1 1 1 1 Clr5 domain SKG6 PF08693.10 KKK19952.1 - 0.00059 19.2 0.7 0.0015 17.9 0.7 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Podoplanin PF05808.11 KKK19952.1 - 0.027 14.6 10.2 0.025 14.7 9.1 1.5 1 1 0 1 1 1 0 Podoplanin Sporozoite_P67 PF05642.11 KKK19952.1 - 0.23 9.5 11.4 0.34 8.9 11.4 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Peroxin-13_N PF04088.13 KKK19953.1 - 1.4e-52 177.8 0.4 2.1e-52 177.2 0.4 1.3 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_2 PF07653.17 KKK19953.1 - 1.6e-09 37.3 0.0 3e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KKK19953.1 - 1.9e-08 33.8 0.0 3.2e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KKK19953.1 - 3.3e-06 26.9 0.1 5.5e-06 26.2 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain hSH3 PF14603.6 KKK19953.1 - 0.18 12.3 0.0 0.31 11.5 0.0 1.3 1 0 0 1 1 1 0 Helically-extended SH3 domain Pex2_Pex12 PF04757.14 KKK19953.1 - 0.19 11.3 0.0 0.3 10.7 0.0 1.3 1 0 0 1 1 1 0 Pex2 / Pex12 amino terminal region ERO1 PF04137.15 KKK19954.1 - 7.1e-135 449.7 0.0 9.6e-135 449.3 0.0 1.2 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) P-II PF00543.22 KKK19954.1 - 0.18 12.4 0.0 0.33 11.6 0.0 1.3 1 0 0 1 1 1 0 Nitrogen regulatory protein P-II Pal1 PF08316.11 KKK19955.1 - 7.1e-11 43.0 0.0 9.9e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 Pal1 cell morphology protein DUF3807 PF12720.7 KKK19956.1 - 4e-39 134.8 0.1 6.8e-39 134.0 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3807) HVSL PF09749.9 KKK19956.1 - 8.5e-27 94.2 0.1 1.2e-26 93.7 0.1 1.2 1 0 0 1 1 1 1 Uncharacterised conserved protein MFS_1 PF07690.16 KKK19957.1 - 2.3e-25 89.3 65.1 3.7e-17 62.3 33.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 KKK19957.1 - 0.15 11.4 28.9 0.23 10.7 28.9 1.6 1 1 0 1 1 1 0 Uncharacterised MFS-type transporter YbfB AMP-binding PF00501.28 KKK19957.1 - 2.3 6.7 3.5 0.49 8.9 0.1 1.5 2 0 0 2 2 2 0 AMP-binding enzyme Aa_trans PF01490.18 KKK19958.1 - 3.8e-43 147.7 34.8 4.6e-43 147.5 34.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein UPF0052 PF01933.18 KKK19980.1 - 1.7e-60 204.8 0.0 2.2e-60 204.4 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 DNApol_Exo PF18136.1 KKK19981.1 - 9.2e-106 353.1 0.1 1.5e-105 352.4 0.1 1.3 1 0 0 1 1 1 1 DNA mitochondrial polymerase exonuclease domain DNA_pol_A PF00476.20 KKK19981.1 - 6.2e-58 196.6 0.0 9.9e-58 196.0 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family A Mad3_BUB1_I PF08311.12 KKK19981.1 - 0.011 15.7 0.6 0.028 14.4 0.6 1.6 1 0 0 1 1 1 0 Mad3/BUB1 homology region 1 DNA_pol_A_exo1 PF01612.20 KKK19981.1 - 0.096 12.4 0.3 1.1 8.9 0.3 2.6 1 1 0 1 1 1 0 3'-5' exonuclease Nup192 PF11894.8 KKK19982.1 - 0 1406.1 8.6 0 1405.9 8.6 1.0 1 0 0 1 1 1 1 Nuclear pore complex scaffold, nucleoporins 186/192/205 DCB PF16213.5 KKK19982.1 - 0.018 14.7 3.0 0.2 11.3 1.3 3.3 3 1 0 3 3 3 0 Dimerisation and cyclophilin-binding domain of Mon2 Hormone_3 PF00159.18 KKK19982.1 - 0.11 12.6 0.0 23 5.1 0.0 2.7 2 0 0 2 2 2 0 Pancreatic hormone peptide PI3_PI4_kinase PF00454.27 KKK19983.1 - 9.5e-52 176.3 0.5 2.8e-51 174.7 0.0 1.9 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase TAN PF11640.8 KKK19983.1 - 6.1e-50 169.3 1.7 4e-49 166.6 1.7 2.6 1 0 0 1 1 1 1 Telomere-length maintenance and DNA damage repair FATC PF02260.20 KKK19983.1 - 1.3e-12 47.3 1.0 1.8e-10 40.4 0.1 3.5 3 0 0 3 3 3 1 FATC domain FAT PF02259.23 KKK19983.1 - 9.5e-06 25.0 4.7 2.3e-05 23.8 4.7 1.6 1 0 0 1 1 1 1 FAT domain Dak1 PF02733.17 KKK19984.1 - 3.6e-106 354.6 0.1 7e-106 353.6 0.1 1.5 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 KKK19984.1 - 1e-46 159.0 0.2 2.1e-46 158.0 0.2 1.6 1 0 0 1 1 1 1 DAK2 domain Cullin PF00888.22 KKK19985.1 - 5.7e-180 600.0 0.0 7e-180 599.7 0.0 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 KKK19985.1 - 7.9e-24 83.5 1.2 1.8e-23 82.3 1.2 1.7 1 0 0 1 1 1 1 Cullin protein neddylation domain HTH_38 PF13936.6 KKK19985.1 - 0.036 13.8 0.0 0.11 12.2 0.0 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain HbrB PF08539.11 KKK19985.1 - 0.093 12.7 0.0 0.39 10.7 0.0 2.0 1 1 0 1 1 1 0 HbrB-like QSOX_Trx1 PF18108.1 KKK19985.1 - 0.12 12.6 0.1 0.44 10.8 0.1 2.0 1 0 0 1 1 1 0 QSOX Trx-like domain GATA PF00320.27 KKK19986.1 - 8.6e-06 25.3 4.5 0.00062 19.3 0.8 2.5 2 0 0 2 2 2 2 GATA zinc finger zf-RING_7 PF02591.15 KKK19986.1 - 0.072 13.3 0.8 0.17 12.1 0.8 1.6 1 0 0 1 1 1 0 C4-type zinc ribbon domain zf-C3HC4 PF00097.25 KKK19988.1 - 4.5e-09 36.0 4.6 1e-08 34.9 4.6 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KKK19988.1 - 9.4e-09 35.0 8.0 2.8e-08 33.5 8.0 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KKK19988.1 - 9.5e-08 32.0 6.8 4e-07 30.0 2.4 2.4 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 KKK19988.1 - 1.4e-07 31.4 7.1 2.7e-07 30.4 7.1 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KKK19988.1 - 1.5e-07 31.1 4.2 1.5e-07 31.1 4.2 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KKK19988.1 - 1.2e-06 28.7 8.8 2.4e-06 27.8 8.8 1.5 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.6 KKK19988.1 - 2e-05 24.6 6.0 0.00018 21.6 6.4 2.3 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 KKK19988.1 - 0.00012 21.8 8.4 0.00068 19.4 8.5 2.1 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-Nse PF11789.8 KKK19988.1 - 0.00072 19.3 0.4 0.0024 17.7 0.5 1.8 1 1 1 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zf-Di19 PF05605.12 KKK19988.1 - 0.0018 18.6 6.4 0.031 14.6 1.2 2.3 1 1 1 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding FANCL_C PF11793.8 KKK19988.1 - 0.051 13.8 4.1 0.19 11.9 4.1 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain His_Me_b4a2 PF18275.1 KKK19988.1 - 0.082 13.0 1.3 0.19 11.8 1.3 1.6 1 0 0 1 1 1 0 His-Me finger endonuclease beta4-alpha2 domain DNA_ligase_ZBD PF03119.16 KKK19988.1 - 0.14 12.2 2.2 3.1 7.9 0.0 2.6 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain Rad50_zn_hook PF04423.14 KKK19988.1 - 0.15 11.9 3.9 0.8 9.6 0.2 2.7 3 0 0 3 3 3 0 Rad50 zinc hook motif zf-RING_4 PF14570.6 KKK19988.1 - 0.3 10.9 7.5 1.4 8.8 7.5 2.1 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_10 PF16685.5 KKK19988.1 - 0.42 10.8 4.4 0.15 12.2 1.5 1.8 2 0 0 2 2 2 0 zinc RING finger of MSL2 zf-rbx1 PF12678.7 KKK19988.1 - 1.1 9.6 9.6 3.9 7.8 9.6 1.9 1 1 0 1 1 1 0 RING-H2 zinc finger domain zinc-ribbons_6 PF07191.12 KKK19988.1 - 1.3 9.1 5.7 45 4.1 5.9 2.3 1 1 1 2 2 2 0 zinc-ribbons Auto_anti-p27 PF06677.12 KKK19988.1 - 4.9 7.4 10.2 15 5.9 4.2 2.3 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zf-RING_6 PF14835.6 KKK19988.1 - 6.2 6.8 7.4 7.8 6.5 4.2 2.4 2 1 0 2 2 2 0 zf-RING of BARD1-type protein zf-H2C2_2 PF13465.6 KKK19988.1 - 6.9 7.3 9.5 2.1 8.9 0.3 2.7 3 0 0 3 3 2 0 Zinc-finger double domain CorA PF01544.18 KKK19989.1 - 5.4e-26 91.6 9.5 2.3e-18 66.5 1.4 3.3 3 0 0 3 3 3 3 CorA-like Mg2+ transporter protein DUF1003 PF06210.11 KKK19989.1 - 0.019 15.0 1.3 0.25 11.5 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1003) DUF1143 PF06608.11 KKK19989.1 - 0.16 12.0 0.2 0.28 11.2 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1143) GTP_EFTU PF00009.27 KKK19990.1 - 4e-19 68.9 0.1 1.4e-18 67.2 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 KKK19990.1 - 4e-06 27.1 0.8 1.3e-05 25.5 0.8 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D3 PF03143.17 KKK19990.1 - 5e-05 23.6 0.0 0.00012 22.3 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain PduV-EutP PF10662.9 KKK19990.1 - 0.0082 15.9 1.0 0.47 10.2 0.1 3.1 2 1 1 3 3 3 1 Ethanolamine utilisation - propanediol utilisation RsgA_GTPase PF03193.16 KKK19990.1 - 0.026 14.5 0.3 3.4 7.6 0.0 2.8 2 0 0 2 2 2 0 RsgA GTPase MMR_HSR1 PF01926.23 KKK19990.1 - 0.03 14.4 0.1 0.086 12.9 0.1 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase tRNA-synt_His PF13393.6 KKK19991.1 - 9e-37 127.0 0.0 2.6e-28 99.2 0.0 3.0 2 1 0 2 2 2 2 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 KKK19991.1 - 5.7e-12 45.6 0.0 1.3e-11 44.5 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain Glyoxalase_2 PF12681.7 KKK19991.1 - 0.023 14.6 0.0 0.044 13.7 0.0 1.5 1 0 0 1 1 1 0 Glyoxalase-like domain SNF2_N PF00176.23 KKK19992.1 - 2.5e-70 236.9 0.0 3.4e-70 236.5 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.11 KKK19992.1 - 1.7e-24 85.5 0.0 3e-24 84.8 0.0 1.4 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.31 KKK19992.1 - 3.9e-14 52.9 0.0 9.8e-14 51.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.6 KKK19992.1 - 0.00027 20.7 4.6 0.0006 19.6 4.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KKK19992.1 - 0.00045 20.0 8.1 0.00082 19.2 8.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KKK19992.1 - 0.00051 19.8 4.7 0.00094 19.0 4.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KKK19992.1 - 0.00094 19.2 7.9 0.002 18.1 7.9 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 KKK19992.1 - 0.0014 18.9 8.2 0.003 17.8 8.2 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 KKK19992.1 - 0.0037 17.2 6.2 0.0073 16.3 6.2 1.5 1 0 0 1 1 1 1 zinc-RING finger domain UBA_4 PF14555.6 KKK19992.1 - 0.065 13.1 0.0 0.17 11.7 0.0 1.7 1 0 0 1 1 1 0 UBA-like domain zf-C3HC4_4 PF15227.6 KKK19992.1 - 0.21 11.8 7.9 0.39 10.9 7.9 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 KKK19992.1 - 1.4 8.8 7.9 6.5 6.7 7.9 2.0 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 KKK19992.1 - 5.5 7.2 6.6 2.6 8.3 3.9 1.8 2 0 0 2 2 2 0 zinc RING finger of MSL2 SQS_PSY PF00494.19 KKK19993.1 - 8.7e-36 123.8 0.2 1.4e-35 123.1 0.2 1.2 1 0 0 1 1 1 1 Squalene/phytoene synthase SQS_PSY PF00494.19 KKK19994.1 - 4.9e-11 42.6 0.1 6.2e-11 42.3 0.1 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase TRAPP PF04051.16 KKK19995.1 - 5e-40 136.6 0.0 6.6e-40 136.2 0.0 1.2 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component NAD_kinase PF01513.21 KKK19996.1 - 1.6e-68 231.0 0.0 2.2e-68 230.6 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase DUF2848 PF11010.8 KKK19996.1 - 0.03 13.9 0.0 0.047 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2848) DUF1583 PF07622.11 KKK19996.1 - 0.055 12.2 0.0 0.08 11.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1583) Rep_fac-A_3 PF08661.11 KKK19997.1 - 5.2e-24 84.6 0.0 5.7e-24 84.5 0.0 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 Ten1 PF12658.7 KKK19997.1 - 0.082 12.9 0.0 1.5 8.7 0.0 2.0 1 1 0 1 1 1 0 Telomere capping, CST complex subunit MFAP1 PF06991.11 KKK19998.1 - 1.3e-68 231.1 28.2 1.3e-68 231.1 28.2 3.4 2 1 1 3 3 3 1 Microfibril-associated/Pre-mRNA processing NAD_binding_4 PF07993.12 KKK20000.1 - 4.4e-35 121.1 0.0 5.6e-35 120.7 0.0 1.1 1 0 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.15 KKK20000.1 - 1.8e-06 27.3 0.0 2.7e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 KKK20000.1 - 0.055 13.4 0.0 0.089 12.7 0.0 1.3 1 0 0 1 1 1 0 KR domain Zn_clus PF00172.18 KKK20001.1 - 2.9e-10 40.1 9.5 5.1e-10 39.3 9.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KKK20001.1 - 4.6e-05 22.4 0.7 6.9e-05 21.8 0.7 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_trans_1_4 PF13692.6 KKK20002.1 - 4.2e-08 33.7 0.0 7.2e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 KKK20002.1 - 5.2e-07 29.3 0.0 8.9e-07 28.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 KKK20002.1 - 2.9e-05 24.4 0.0 5.1e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KKK20002.1 - 0.011 15.8 0.2 0.029 14.4 0.2 1.8 1 0 0 1 1 1 0 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 KKK20002.1 - 0.013 15.9 0.0 0.033 14.6 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferase 4-like domain Cation_efflux PF01545.21 KKK20003.1 - 1.3e-45 155.6 12.7 1.3e-45 155.6 12.7 2.1 2 0 0 2 2 2 1 Cation efflux family UQ_con PF00179.26 KKK20004.1 - 4e-51 172.4 0.0 4.5e-51 172.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KKK20004.1 - 0.0016 18.1 0.0 0.0018 18.0 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 KKK20004.1 - 0.078 13.3 0.0 0.15 12.4 0.0 1.5 1 1 0 1 1 1 0 RWD domain Kinesin PF00225.23 KKK20005.1 - 3.3e-111 371.4 0.1 7.8e-111 370.2 0.1 1.7 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KKK20005.1 - 5.9e-26 91.2 0.0 1.9e-25 89.5 0.0 1.9 1 0 0 1 1 1 1 Microtubule binding DinB_2 PF12867.7 KKK20005.1 - 0.023 15.2 0.3 0.37 11.3 0.0 3.1 3 0 0 3 3 3 0 DinB superfamily DUF1398 PF07166.11 KKK20005.1 - 0.047 13.7 0.0 0.17 11.9 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1398) STPPase_N PF16891.5 KKK20005.1 - 1 9.8 5.4 17 5.9 0.2 3.1 3 0 0 3 3 3 0 Serine-threonine protein phosphatase N-terminal domain TFIIIC_delta PF12657.7 KKK20006.1 - 1.5e-44 152.1 0.3 2.6e-44 151.4 0.3 1.4 1 0 0 1 1 1 1 Transcription factor IIIC subunit delta N-term zf-TFIIIC PF12660.7 KKK20006.1 - 3.4e-32 110.4 2.5 6.9e-32 109.4 2.5 1.6 1 0 0 1 1 1 1 Putative zinc-finger of transcription factor IIIC complex Type2_restr_D3 PF16902.5 KKK20006.1 - 0.29 11.1 0.4 0.72 9.8 0.1 1.7 2 0 0 2 2 2 0 Type-2 restriction enzyme D3 domain Shugoshin_N PF07558.11 KKK20007.1 - 5.1e-19 67.9 4.6 1.1e-18 66.8 4.6 1.6 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region Shugoshin_C PF07557.11 KKK20007.1 - 1.3e-11 44.1 3.2 5.4e-11 42.1 3.2 2.2 1 0 0 1 1 1 1 Shugoshin C terminus bZIP_2 PF07716.15 KKK20007.1 - 7.7 6.7 9.2 0.12 12.5 0.5 2.6 2 0 0 2 2 2 0 Basic region leucine zipper DASH_Dad2 PF08654.10 KKK20008.1 - 1.7e-34 118.2 2.1 2.4e-34 117.7 2.1 1.2 1 0 0 1 1 1 1 DASH complex subunit Dad2 NPV_P10 PF05531.12 KKK20008.1 - 0.00058 20.3 3.2 0.36 11.3 0.7 2.1 2 0 0 2 2 2 2 Nucleopolyhedrovirus P10 protein SLX9 PF15341.6 KKK20008.1 - 0.0028 18.1 3.2 0.0036 17.7 3.2 1.2 1 0 0 1 1 1 1 Ribosome biogenesis protein SLX9 Seryl_tRNA_N PF02403.22 KKK20008.1 - 0.009 16.2 0.8 0.009 16.2 0.8 1.8 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain DASH_Duo1 PF08651.10 KKK20008.1 - 0.019 14.7 0.5 0.035 13.9 0.5 1.4 1 0 0 1 1 1 0 DASH complex subunit Duo1 DUF1664 PF07889.12 KKK20008.1 - 0.029 14.4 0.1 0.038 14.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Fmp27_WPPW PF10359.9 KKK20008.1 - 0.086 11.7 4.4 0.096 11.5 4.4 1.0 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain ECM11 PF15463.6 KKK20008.1 - 0.11 13.1 2.5 6.5 7.3 0.1 2.3 2 0 0 2 2 2 0 Extracellular mutant protein 11 bZIP_1 PF00170.21 KKK20008.1 - 0.57 10.3 6.3 0.099 12.7 2.5 1.8 2 1 0 2 2 2 0 bZIP transcription factor ZapB PF06005.12 KKK20008.1 - 0.6 10.6 6.2 0.82 10.2 4.8 2.1 1 1 0 1 1 1 0 Cell division protein ZapB CRM1_C PF08767.11 KKK20009.1 - 3.5e-139 463.4 11.2 3.5e-139 463.4 11.2 2.8 2 1 0 2 2 2 1 CRM1 C terminal Xpo1 PF08389.12 KKK20009.1 - 2.6e-42 144.4 10.3 1.5e-41 141.9 6.4 3.5 2 1 1 3 3 3 1 Exportin 1-like protein CRM1_repeat_2 PF18784.1 KKK20009.1 - 4.1e-34 116.0 3.9 2.2e-33 113.7 3.9 2.4 2 0 0 2 2 2 1 CRM1 / Exportin repeat 2 CRM1_repeat_3 PF18787.1 KKK20009.1 - 4.9e-29 100.2 5.2 6.9e-29 99.7 0.7 3.1 3 0 0 3 3 3 1 CRM1 / Exportin repeat 3 CRM1_repeat PF18777.1 KKK20009.1 - 8.9e-20 69.9 1.1 2.2e-19 68.7 1.1 1.7 1 0 0 1 1 1 1 Chromosome region maintenance or exportin repeat IBN_N PF03810.19 KKK20009.1 - 0.00055 19.8 0.0 0.0082 16.0 0.0 2.9 1 1 0 1 1 1 1 Importin-beta N-terminal domain DUF3385 PF11865.8 KKK20009.1 - 0.0073 16.2 1.8 0.38 10.7 0.0 4.0 5 0 0 5 5 5 1 Domain of unknown function (DUF3385) Hemocyanin_M PF00372.19 KKK20009.1 - 0.034 13.3 0.0 0.085 12.0 0.0 1.6 1 0 0 1 1 1 0 Hemocyanin, copper containing domain DRE2_N PF16803.5 KKK20009.1 - 0.054 13.8 0.0 0.33 11.2 0.0 2.4 2 0 0 2 2 2 0 Fe-S cluster assembly protein DRE2 N-terminus HD_assoc PF13286.6 KKK20009.1 - 0.19 12.3 1.9 26 5.4 0.1 3.7 4 0 0 4 4 4 0 Phosphohydrolase-associated domain PPI_Ypi1 PF07491.11 KKK20010.1 - 2.3e-23 81.8 8.3 2.3e-23 81.8 8.3 2.5 2 1 0 2 2 2 1 Protein phosphatase inhibitor TFIIF_alpha PF05793.12 KKK20010.1 - 0.019 13.6 10.4 0.019 13.6 10.4 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Neur_chan_memb PF02932.16 KKK20010.1 - 0.77 9.8 3.4 0.79 9.7 3.4 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CDC45 PF02724.14 KKK20010.1 - 2.1 6.5 8.5 2.2 6.5 8.5 1.0 1 0 0 1 1 1 0 CDC45-like protein GIT_SHD PF08518.11 KKK20028.1 - 3.3e-21 74.6 9.8 8.5e-12 44.5 1.4 2.9 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT GIT1_C PF12205.8 KKK20028.1 - 0.0001 22.4 1.0 0.00097 19.2 0.0 2.8 2 0 0 2 2 2 1 G protein-coupled receptor kinase-interacting protein 1 C term PspB PF06667.12 KKK20028.1 - 0.0016 18.4 0.7 0.0087 16.1 0.7 2.3 1 0 0 1 1 1 1 Phage shock protein B Phage_GP20 PF06810.11 KKK20028.1 - 0.01 15.7 16.1 2 8.2 12.4 2.8 2 1 1 3 3 3 0 Phage minor structural protein GP20 LPP PF04728.13 KKK20028.1 - 9.3 6.7 8.2 2 8.9 1.3 3.6 3 1 1 4 4 4 0 Lipoprotein leucine-zipper Pro_isomerase PF00160.21 KKK20029.1 - 3e-24 86.1 0.0 4.3e-24 85.6 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD FA_desaturase PF00487.24 KKK20032.1 - 7.4e-23 81.7 19.6 1.7e-22 80.5 19.6 1.6 1 1 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 KKK20032.1 - 3.7e-05 23.9 0.0 9.1e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) MARVEL PF01284.23 KKK20032.1 - 0.74 9.8 5.0 6.4 6.8 3.2 2.3 2 0 0 2 2 2 0 Membrane-associating domain LicD PF04991.13 KKK20033.1 - 3.2e-26 92.9 5.3 7.7e-19 68.7 2.2 2.2 1 1 1 2 2 2 2 LicD family UvrD-helicase PF00580.21 KKK20033.1 - 0.061 12.8 0.1 0.089 12.3 0.1 1.3 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain Glyco_hydro_43 PF04616.14 KKK20034.1 - 8.7e-52 176.2 6.3 1.8e-28 99.7 0.7 2.2 1 1 1 2 2 2 2 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 KKK20034.1 - 2.4e-17 63.3 0.0 4.1e-17 62.6 0.0 1.3 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain Pkinase PF00069.25 KKK20034.1 - 5.9e-10 39.0 0.0 1.6e-09 37.6 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK20034.1 - 6.4e-06 25.6 0.0 1.1e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KKK20034.1 - 0.0046 16.9 2.7 0.012 15.5 1.0 2.2 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.14 KKK20034.1 - 0.005 16.2 0.3 0.014 14.8 0.1 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 KKK20034.1 - 0.0068 16.1 0.0 0.048 13.3 0.0 2.0 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 KKK20034.1 - 0.059 12.7 0.0 0.23 10.7 0.0 1.8 2 0 0 2 2 2 0 Kinase-like APH PF01636.23 KKK20035.1 - 0.00031 20.7 0.0 0.00034 20.6 0.0 1.0 1 0 0 1 1 1 1 Phosphotransferase enzyme family SUI1 PF01253.22 KKK20037.1 - 8.3e-22 77.5 0.1 1.5e-21 76.7 0.1 1.5 1 0 0 1 1 1 1 Translation initiation factor SUI1 Pre-PUA PF17832.1 KKK20037.1 - 1.4e-09 38.5 0.1 6.2e-08 33.2 0.1 2.9 2 1 0 2 2 2 1 Pre-PUA-like domain Dabb PF07876.12 KKK20037.1 - 0.008 16.8 0.0 0.019 15.6 0.0 1.6 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Kin17_mid PF10357.9 KKK20037.1 - 0.18 11.8 0.2 0.38 10.7 0.0 1.5 2 0 0 2 2 2 0 Domain of Kin17 curved DNA-binding protein Chitin_synth_2 PF03142.15 KKK20038.1 - 7.4e-24 84.3 8.0 2.1e-22 79.4 1.1 2.7 2 1 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 KKK20038.1 - 2.7e-14 53.6 5.2 2.7e-14 53.6 5.2 2.6 2 2 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KKK20038.1 - 1.3e-10 41.5 0.1 5.2e-10 39.6 0.1 1.8 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KKK20038.1 - 0.074 12.9 0.1 7.8 6.3 0.1 2.4 2 0 0 2 2 2 0 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 KKK20038.1 - 0.14 11.7 0.7 5.1 6.5 0.7 2.4 1 1 0 1 1 1 0 Glycosyl transferase family 21 Benyvirus_14KDa PF07255.11 KKK20038.1 - 0.15 12.3 0.3 0.3 11.3 0.3 1.4 1 0 0 1 1 1 0 Benyvirus 14KDa protein TRAPPC10 PF12584.8 KKK20039.1 - 9.7e-41 139.1 0.0 1.8e-40 138.2 0.0 1.5 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 Ank_5 PF13857.6 KKK20040.1 - 4.5e-11 42.8 0.5 2e-07 31.1 0.2 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 KKK20040.1 - 3.5e-07 30.7 0.4 6.9e-06 26.5 0.2 2.5 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 KKK20040.1 - 6.2e-07 29.6 7.5 0.0011 19.3 1.1 2.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 KKK20040.1 - 8.8e-07 29.4 0.0 1.7e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) TIG PF01833.24 KKK20040.1 - 6.9e-06 26.1 0.1 3.4e-05 23.8 0.0 2.2 2 0 0 2 2 2 1 IPT/TIG domain Ank_3 PF13606.6 KKK20040.1 - 4e-05 23.7 0.3 0.057 14.0 0.2 2.6 2 0 0 2 2 2 2 Ankyrin repeat TMEM51 PF15345.6 KKK20040.1 - 0.025 14.4 0.4 0.025 14.4 0.4 2.7 3 0 0 3 3 3 0 Transmembrane protein 51 Glyco_hydro_61 PF03443.14 KKK20041.1 - 2.1e-68 230.3 0.4 2.1e-68 230.3 0.4 1.7 2 0 0 2 2 2 1 Glycosyl hydrolase family 61 DUF966 PF06136.13 KKK20041.1 - 0.11 12.2 10.5 0.14 11.8 10.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) SOG2 PF10428.9 KKK20041.1 - 0.21 10.8 20.9 0.25 10.5 20.9 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein GREB1 PF15782.5 KKK20041.1 - 9.3 3.2 12.0 12 2.9 12.0 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer La PF05383.17 KKK20042.1 - 8e-22 77.1 0.1 1.3e-21 76.3 0.1 1.4 1 0 0 1 1 1 1 La domain RRM_1 PF00076.22 KKK20042.1 - 1.7e-07 30.9 0.1 7.6e-07 28.9 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HSP70 PF00012.20 KKK20043.1 - 1.3e-140 469.5 6.1 1.3e-140 469.5 6.1 3.2 1 1 1 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 KKK20043.1 - 1.1e-12 47.5 0.1 1.8e-12 46.8 0.1 1.3 1 0 0 1 1 1 1 MreB/Mbl protein FtsA PF14450.6 KKK20043.1 - 0.001 19.5 0.4 2.5 8.5 0.0 3.4 2 2 0 2 2 2 2 Cell division protein FtsA LapD_MoxY_N PF16448.5 KKK20043.1 - 0.021 14.7 0.1 0.056 13.3 0.1 1.7 1 0 0 1 1 1 0 LapD/MoxY periplasmic domain DUF2746 PF10874.8 KKK20043.1 - 0.023 15.1 0.1 0.24 11.9 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2746) FGGY_C PF02782.16 KKK20043.1 - 0.098 12.4 0.1 0.33 10.7 0.0 2.0 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain Ketoacyl-synt_C PF02801.22 KKK20043.1 - 0.14 12.2 0.0 0.58 10.2 0.0 2.1 1 0 0 1 1 1 0 Beta-ketoacyl synthase, C-terminal domain GCFC PF07842.12 KKK20044.1 - 1.6e-89 300.2 3.0 1.6e-89 300.2 3.0 1.6 2 0 0 2 2 2 1 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.23 KKK20044.1 - 7.4e-14 51.4 1.5 1.3e-13 50.6 1.5 1.4 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 KKK20044.1 - 1.1e-06 28.6 0.2 3.8e-06 26.9 0.2 2.0 1 0 0 1 1 1 1 G-patch domain DUF3425 PF11905.8 KKK20044.1 - 0.025 14.5 0.0 0.081 12.9 0.0 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF3425) DUF5082 PF16888.5 KKK20044.1 - 0.061 13.6 1.8 0.49 10.7 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) PilX PF13681.6 KKK20044.1 - 0.15 12.5 0.0 0.69 10.3 0.0 2.1 2 0 0 2 2 2 0 Type IV pilus assembly protein PilX C-term SHR-BD PF06650.12 KKK20045.1 - 5.4e-99 331.0 0.0 5.3e-98 327.7 0.0 2.6 2 1 0 2 2 2 1 SHR-binding domain of vacuolar-sorting associated protein 13 VPS13_mid_rpt PF16910.5 KKK20045.1 - 1.1e-89 300.0 9.2 4.9e-87 291.3 0.5 4.5 4 0 0 4 4 4 2 Repeating coiled region of VPS13 VPS13 PF16908.5 KKK20045.1 - 5.9e-80 268.5 0.7 6.2e-78 261.8 0.0 4.1 5 0 0 5 5 5 1 Vacuolar sorting-associated protein 13, N-terminal VPS13_C PF16909.5 KKK20045.1 - 2.6e-73 245.6 2.8 1.2e-67 227.2 0.2 2.6 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal Chorein_N PF12624.7 KKK20045.1 - 2.2e-40 137.4 0.0 6e-40 136.0 0.0 1.8 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 ATG_C PF09333.11 KKK20045.1 - 2.2e-06 27.9 1.0 5.1e-06 26.7 0.0 2.2 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain MFS_1 PF07690.16 KKK20046.1 - 4.8e-21 75.1 36.9 1.8e-15 56.8 21.7 2.8 2 1 1 3 3 3 2 Major Facilitator Superfamily DUF2749 PF10907.8 KKK20046.1 - 0.11 12.7 0.0 0.35 11.1 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2749) DUF3429 PF11911.8 KKK20047.1 - 8.2e-44 149.4 12.7 1.2e-43 148.9 12.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) F-box PF00646.33 KKK20048.1 - 0.033 14.1 2.3 0.035 14.0 0.0 2.2 2 0 0 2 2 2 0 F-box domain F-box-like PF12937.7 KKK20048.1 - 6.7 6.7 8.8 0.66 9.9 0.2 2.9 3 0 0 3 3 3 0 F-box-like Sod_Fe_C PF02777.18 KKK20049.1 - 2.7e-37 127.0 1.5 3.5e-37 126.7 0.4 1.7 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 KKK20049.1 - 1.5e-28 99.1 3.2 2.5e-28 98.3 3.2 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain DAHP_synth_2 PF01474.16 KKK20054.1 - 5.1e-125 417.4 0.0 5.1e-91 305.4 0.0 2.0 1 1 1 2 2 2 2 Class-II DAHP synthetase family DUF2868 PF11067.8 KKK20054.1 - 0.015 14.9 0.0 0.019 14.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) ABC1 PF03109.16 KKK20055.1 - 7e-21 74.6 0.9 2.9e-20 72.6 0.0 2.3 2 1 0 2 2 2 1 ABC1 family Lactamase_B PF00753.27 KKK20056.1 - 2.3e-06 27.8 1.2 0.00023 21.2 0.2 2.3 1 1 0 2 2 2 2 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KKK20056.1 - 0.00088 18.8 1.2 0.0023 17.5 0.1 2.1 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Pkinase PF00069.25 KKK20112.1 - 2.3e-54 184.5 0.0 3.4e-54 184.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK20112.1 - 2.5e-23 82.7 0.0 9e-23 80.9 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 KKK20112.1 - 0.049 12.6 0.1 0.075 12.0 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase DHR10 PF18595.1 KKK20113.1 - 0.24 11.5 3.1 0.4 10.8 3.1 1.2 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain TMA7 PF09072.10 KKK20114.1 - 7e-23 81.2 16.6 7.9e-23 81.1 16.6 1.0 1 0 0 1 1 1 1 Translation machinery associated TMA7 Condensation PF00668.20 KKK20115.1 - 2.7e-107 359.3 0.0 7e-40 137.1 0.1 3.1 3 0 0 3 3 3 3 Condensation domain PP-binding PF00550.25 KKK20115.1 - 4e-31 107.2 0.1 2.3e-12 47.1 0.0 3.8 3 0 0 3 3 3 3 Phosphopantetheine attachment site AMP-binding PF00501.28 KKK20115.1 - 5.2e-30 104.4 0.7 7.6e-30 103.8 0.7 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Transferase PF02458.15 KKK20115.1 - 2.2e-05 23.3 0.0 0.18 10.4 0.0 3.4 3 0 0 3 3 3 2 Transferase family DUF1524 PF07510.11 KKK20115.1 - 0.15 12.0 0.0 0.4 10.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1524) AMP-binding PF00501.28 KKK20116.1 - 1.4e-172 574.1 0.0 2.3e-68 230.7 0.0 3.3 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.20 KKK20116.1 - 4.1e-47 160.9 0.0 9.2e-30 103.7 0.0 2.4 2 0 0 2 2 2 2 Condensation domain PP-binding PF00550.25 KKK20116.1 - 2.6e-15 56.5 1.6 9.4e-07 29.1 0.3 2.8 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KKK20116.1 - 7e-12 46.2 0.3 3.3e-07 31.2 0.3 3.3 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain AMP-binding PF00501.28 KKK20117.1 - 4.7e-104 348.3 0.0 6.2e-104 347.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KKK20117.1 - 1.9e-11 44.8 0.0 3.9e-11 43.8 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Glyco_hydro_61 PF03443.14 KKK20118.1 - 0.0043 17.0 0.0 0.0085 16.1 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 61 SPX PF03105.19 KKK20118.1 - 0.35 10.7 3.3 0.34 10.8 3.3 1.1 1 0 0 1 1 1 0 SPX domain SSP160 PF06933.11 KKK20118.1 - 0.42 8.7 16.3 0.5 8.5 16.3 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 SOG2 PF10428.9 KKK20118.1 - 1.5 7.9 13.5 1.9 7.6 13.5 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Sporozoite_P67 PF05642.11 KKK20118.1 - 4.6 5.2 13.5 5.7 4.9 13.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen UvdE PF03851.14 KKK20119.1 - 2.1e-110 368.3 0.0 2.8e-110 367.9 0.0 1.2 1 0 0 1 1 1 1 UV-endonuclease UvdE DUF2183 PF09949.9 KKK20119.1 - 4.4e-31 107.2 0.0 1e-30 106.0 0.0 1.7 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) CarboxypepD_reg PF13620.6 KKK20119.1 - 0.091 13.1 0.0 0.25 11.6 0.0 1.7 1 0 0 1 1 1 0 Carboxypeptidase regulatory-like domain BCMA-Tall_bind PF09257.10 KKK20119.1 - 2.8 8.1 5.7 0.44 10.7 1.2 2.1 2 0 0 2 2 2 0 BCMA, TALL-1 binding DUF1489 PF07370.11 KKK20124.1 - 0.014 15.1 0.2 0.063 13.0 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1489) F-box PF00646.33 KKK20124.1 - 0.12 12.3 1.1 4 7.4 0.0 2.7 2 0 0 2 2 2 0 F-box domain Methyltransf_25 PF13649.6 KKK20141.1 - 8.1e-14 52.1 0.0 2e-13 50.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KKK20141.1 - 1.6e-12 47.4 0.0 3.3e-12 46.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KKK20141.1 - 5e-11 42.5 0.0 7.8e-11 41.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 KKK20141.1 - 6.1e-10 39.6 0.0 2e-09 38.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KKK20141.1 - 2e-07 31.0 0.0 6.1e-07 29.4 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KKK20141.1 - 3.5e-06 27.7 0.0 7.7e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 KKK20141.1 - 1.7e-05 23.9 0.0 2.5e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) MTS PF05175.14 KKK20141.1 - 2.4e-05 24.0 0.1 5.2e-05 22.9 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase small domain CMAS PF02353.20 KKK20141.1 - 2.8e-05 23.5 0.0 4.1e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.7 KKK20141.1 - 6.9e-05 22.8 0.2 0.00021 21.3 0.1 1.8 1 1 1 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 KKK20141.1 - 0.0004 19.8 0.0 0.00064 19.1 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.6 KKK20141.1 - 0.001 19.1 0.0 0.0021 18.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 KKK20141.1 - 0.0028 17.8 0.0 0.0071 16.5 0.0 1.7 2 0 0 2 2 2 1 FtsJ-like methyltransferase PRMT5 PF05185.16 KKK20141.1 - 0.0072 16.2 0.0 0.014 15.3 0.0 1.4 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_16 PF10294.9 KKK20141.1 - 0.0087 15.8 0.0 0.013 15.2 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase PCMT PF01135.19 KKK20141.1 - 0.023 14.5 0.1 0.038 13.7 0.1 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_4 PF02390.17 KKK20141.1 - 0.032 13.7 0.3 0.068 12.6 0.1 1.6 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_24 PF13578.6 KKK20141.1 - 0.085 13.9 0.0 0.23 12.5 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain DOT1 PF08123.13 KKK20141.1 - 0.1 12.1 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 Rsm22 PF09243.10 KKK20141.1 - 0.12 11.6 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial small ribosomal subunit Rsm22 AAA PF00004.29 KKK20142.1 - 1.3e-40 138.8 0.0 2.6e-40 137.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 KKK20142.1 - 4.1e-19 68.3 0.2 9.1e-19 67.2 0.2 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 KKK20142.1 - 4.6e-10 39.1 0.0 1e-09 38.0 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 KKK20142.1 - 6.5e-05 22.7 0.0 0.00016 21.5 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KKK20142.1 - 9.8e-05 22.4 1.1 0.00028 20.9 0.1 2.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KKK20142.1 - 0.0002 21.8 1.5 0.024 15.0 0.0 2.9 2 1 1 3 3 3 1 AAA ATPase domain AAA_2 PF07724.14 KKK20142.1 - 0.00083 19.5 1.7 0.012 15.8 0.0 3.4 3 1 0 3 3 3 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 KKK20142.1 - 0.0016 18.7 0.7 0.2 11.9 0.0 3.0 2 1 1 3 3 3 1 AAA domain DUF815 PF05673.13 KKK20142.1 - 0.004 16.3 0.0 0.011 15.0 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF815) PhoH PF02562.16 KKK20142.1 - 0.0058 16.1 0.2 0.08 12.4 0.1 2.2 2 0 0 2 2 2 1 PhoH-like protein Mg_chelatase PF01078.21 KKK20142.1 - 0.013 14.9 0.1 0.037 13.4 0.0 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 KKK20142.1 - 0.013 15.6 0.0 0.043 14.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 KKK20142.1 - 0.065 13.0 0.1 0.16 11.7 0.1 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_7 PF12775.7 KKK20142.1 - 0.13 11.8 0.0 0.34 10.4 0.0 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region Atg14 PF10186.9 KKK20142.1 - 0.24 10.4 4.7 2.3 7.2 5.0 2.0 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 AAA_11 PF13086.6 KKK20142.1 - 0.47 10.2 0.0 0.47 10.2 0.0 2.8 2 1 1 3 3 3 0 AAA domain DUF496 PF04363.12 KKK20142.1 - 0.99 9.5 9.2 0.28 11.2 0.4 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF496) CLZ PF16526.5 KKK20142.1 - 4.1 7.8 11.1 0.89 10.0 6.5 2.4 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels TauD PF02668.16 KKK20143.1 - 1.4e-40 139.8 1.6 1.7e-40 139.5 1.6 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 KKK20143.1 - 0.1 11.7 0.1 0.32 10.1 0.0 1.7 2 0 0 2 2 2 0 CsiD Pkinase PF00069.25 KKK20144.1 - 8.9e-69 231.8 0.0 1.2e-68 231.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK20144.1 - 8.3e-31 107.2 0.0 1.2e-30 106.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 KKK20144.1 - 3e-15 56.6 1.7 2.4e-14 53.8 1.7 2.7 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.6 KKK20144.1 - 1.3e-08 34.5 0.0 4.4e-08 32.8 0.0 1.7 1 1 1 2 2 2 1 Kinase-like C2 PF00168.30 KKK20144.1 - 1.9e-08 34.5 0.0 3e-06 27.5 0.1 2.5 2 0 0 2 2 2 1 C2 domain Haspin_kinase PF12330.8 KKK20144.1 - 0.00023 20.2 0.2 0.00044 19.3 0.2 1.4 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KKK20144.1 - 0.0071 16.3 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.6 KKK20144.1 - 0.042 13.5 0.4 3.5 7.2 0.1 2.4 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Choline_kinase PF01633.20 KKK20144.1 - 0.051 13.1 0.1 0.12 12.0 0.1 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.14 KKK20144.1 - 0.1 11.9 0.1 0.16 11.3 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TMA7 PF09072.10 KKK20144.1 - 1.8 9.4 5.0 13 6.7 1.9 2.7 2 0 0 2 2 2 0 Translation machinery associated TMA7 F-box-like PF12937.7 KKK20145.1 - 0.0031 17.4 0.1 0.0093 15.8 0.1 1.8 1 1 0 1 1 1 1 F-box-like DUF3461 PF11944.8 KKK20145.1 - 0.16 12.1 0.0 26 5.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3461) Cwf_Cwc_15 PF04889.12 KKK20145.1 - 1.3 8.7 7.3 2 8.1 7.3 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein NOA36 PF06524.12 KKK20145.1 - 8.6 5.6 7.2 14 4.9 7.2 1.2 1 0 0 1 1 1 0 NOA36 protein PGM_PMM_I PF02878.16 KKK20146.1 - 3.6e-16 59.1 0.1 2e-07 30.8 0.0 2.8 1 1 1 2 2 2 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.20 KKK20146.1 - 5.6e-11 42.5 0.4 2e-10 40.7 0.4 2.0 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_II PF02879.16 KKK20146.1 - 0.00061 20.4 0.1 0.003 18.2 0.1 2.2 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 KKK20146.1 - 0.059 13.6 0.1 0.28 11.4 0.1 2.1 1 1 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III DEAD PF00270.29 KKK20147.1 - 2e-49 167.7 0.0 3.4e-49 167.0 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KKK20147.1 - 4.8e-30 104.2 0.0 4e-29 101.2 0.0 2.5 4 0 0 4 4 4 1 Helicase conserved C-terminal domain ResIII PF04851.15 KKK20147.1 - 8.9e-06 25.8 0.0 2.5e-05 24.4 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF1087 PF06465.13 KKK20147.1 - 0.16 12.0 1.0 0.41 10.7 1.0 1.8 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1087) Per1 PF04080.13 KKK20148.1 - 6.8e-101 337.3 16.8 8.2e-101 337.1 16.8 1.1 1 0 0 1 1 1 1 Per1-like family YWFCY PF14293.6 KKK20148.1 - 3.3 8.1 5.6 8.7 6.7 3.1 2.6 2 1 0 2 2 2 0 YWFCY protein Lum_binding PF00677.17 KKK20149.1 - 1.1e-43 147.1 2.1 5.9e-22 77.5 0.7 2.3 2 0 0 2 2 2 2 Lumazine binding domain Brix PF04427.18 KKK20150.1 - 2.1e-50 171.6 0.3 3.8e-50 170.7 0.3 1.4 1 0 0 1 1 1 1 Brix domain RAP1 PF07218.11 KKK20150.1 - 0.52 8.5 10.1 0.65 8.2 10.1 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) PBP_sp32 PF07222.12 KKK20150.1 - 4.9 6.5 8.9 8 5.8 8.9 1.4 1 0 0 1 1 1 0 Proacrosin binding protein sp32 PHD PF00628.29 KKK20151.1 - 4.1e-10 39.4 9.1 6.9e-10 38.7 9.1 1.4 1 0 0 1 1 1 1 PHD-finger FYVE_2 PF02318.16 KKK20151.1 - 0.00094 19.4 1.9 0.0015 18.7 1.9 1.2 1 0 0 1 1 1 1 FYVE-type zinc finger C1_1 PF00130.22 KKK20151.1 - 0.0012 18.7 3.1 0.0026 17.6 3.1 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Herpes_UL52 PF03121.15 KKK20151.1 - 0.013 15.4 2.1 0.023 14.6 2.1 1.4 1 0 0 1 1 1 0 Herpesviridae UL52/UL70 DNA primase zf-RRPl_C4 PF17026.5 KKK20151.1 - 0.18 11.9 1.5 0.3 11.2 1.5 1.3 1 0 0 1 1 1 0 Putative ribonucleoprotein zinc-finger pf C4 type PHD_2 PF13831.6 KKK20151.1 - 0.46 10.1 10.5 0.12 11.9 6.0 2.3 2 1 0 2 2 2 0 PHD-finger Prok-RING_1 PF14446.6 KKK20151.1 - 0.53 10.3 5.5 1 9.3 5.5 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 CoA_transf_3 PF02515.17 KKK20152.1 - 8.3e-129 429.9 0.0 9.5e-129 429.7 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III NTP_transf_5 PF14907.6 KKK20153.1 - 0.17 11.5 0.0 2.1 7.9 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised nucleotidyltransferase APH PF01636.23 KKK20159.1 - 0.0028 17.6 0.1 0.041 13.8 0.1 2.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Cu-oxidase_3 PF07732.15 KKK20160.1 - 2.5e-33 114.6 0.0 7.9e-33 113.0 0.0 1.9 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 KKK20160.1 - 2.9e-30 104.8 3.0 1.2e-23 83.3 0.8 3.4 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 KKK20160.1 - 6.7e-16 58.8 0.0 3.5e-15 56.5 0.0 2.2 1 1 0 1 1 1 1 Multicopper oxidase WD40 PF00400.32 KKK20161.1 - 1.7e-12 47.6 18.9 0.007 17.2 0.7 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.11 KKK20161.1 - 0.0011 18.9 0.0 0.0079 16.1 0.0 1.9 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Ccdc124 PF06244.12 KKK20162.1 - 1.4e-30 106.5 18.0 2.6e-29 102.4 18.0 2.1 1 1 0 1 1 1 1 Coiled-coil domain-containing protein 124 /Oxs1 Presenilin PF01080.17 KKK20162.1 - 4.8 5.8 7.5 4.5 5.9 7.5 1.2 1 0 0 1 1 1 0 Presenilin CBFB_NFYA PF02045.15 KKK20165.1 - 1.5e-28 99.2 4.6 3.2e-28 98.1 4.6 1.6 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B Hus1 PF04005.12 KKK20165.1 - 0.05 12.7 0.0 0.1 11.7 0.0 1.4 1 0 0 1 1 1 0 Hus1-like protein TFIIA PF03153.13 KKK20165.1 - 0.16 11.9 30.7 0.21 11.6 30.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MFS_1 PF07690.16 KKK20166.1 - 1.5e-43 149.1 43.8 1.5e-43 149.1 43.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KKK20166.1 - 2.5e-10 39.8 9.7 2.5e-10 39.8 9.7 2.5 1 1 2 3 3 3 1 Sugar (and other) transporter SNF2_N PF00176.23 KKK20167.1 - 2e-68 230.7 0.0 3.2e-68 230.0 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.11 KKK20167.1 - 2.4e-19 69.0 0.0 6.2e-19 67.7 0.0 1.7 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.31 KKK20167.1 - 2.1e-13 50.6 0.0 6.1e-13 49.1 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.6 KKK20167.1 - 2.9e-10 39.8 8.5 6.8e-10 38.6 8.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KKK20167.1 - 7.1e-09 35.9 9.9 9.4e-09 35.5 8.0 2.1 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 KKK20167.1 - 5.1e-08 32.8 5.2 1.5e-07 31.3 5.2 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KKK20167.1 - 5.3e-08 32.6 8.3 5.3e-08 32.6 8.3 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KKK20167.1 - 1.1e-07 31.6 6.6 1.1e-07 31.6 6.6 2.5 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KKK20167.1 - 2.2e-07 31.0 5.1 6.7e-07 29.5 5.1 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-Nse PF11789.8 KKK20167.1 - 2.6e-07 30.3 7.7 3.2e-07 30.1 6.3 1.8 2 0 0 2 2 1 1 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.6 KKK20167.1 - 5.6e-07 29.6 8.4 7.6e-07 29.2 7.1 2.0 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 KKK20167.1 - 7e-06 25.9 6.2 1.7e-05 24.7 6.2 1.7 1 0 0 1 1 1 1 zinc-RING finger domain U-box PF04564.15 KKK20167.1 - 9.7e-06 25.7 0.1 5.6e-05 23.2 0.0 2.2 2 0 0 2 2 2 1 U-box domain zf-ANAPC11 PF12861.7 KKK20167.1 - 0.00014 21.9 0.5 0.0003 20.8 0.5 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 KKK20167.1 - 0.0037 17.0 1.8 0.018 14.8 1.8 2.3 1 0 0 1 1 1 1 RING-like zinc finger Prok-RING_4 PF14447.6 KKK20167.1 - 0.0042 16.9 6.3 0.0042 16.9 6.3 2.0 2 1 0 2 2 1 1 Prokaryotic RING finger family 4 SIMPL PF04402.14 KKK20167.1 - 0.11 13.0 1.7 3.2 8.1 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF541) DUF1644 PF07800.12 KKK20167.1 - 0.34 11.0 4.0 12 6.0 0.3 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1644) zf-RING_4 PF14570.6 KKK20167.1 - 0.82 9.5 6.1 4.1 7.3 6.4 2.0 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain Prok-RING_1 PF14446.6 KKK20167.1 - 0.96 9.4 4.1 21 5.1 0.1 2.4 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 zf-RING_10 PF16685.5 KKK20167.1 - 1.2 9.3 3.7 3.3 7.9 3.7 1.7 1 0 0 1 1 1 0 zinc RING finger of MSL2 GSH_synth_ATP PF03917.17 KKK20168.1 - 3.1e-119 398.1 0.0 2.7e-117 391.7 0.0 2.0 1 1 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 KKK20168.1 - 3.6e-30 104.5 0.0 7.9e-30 103.4 0.0 1.6 1 0 0 1 1 1 1 Eukaryotic glutathione synthase SNF2_N PF00176.23 KKK20169.1 - 6e-37 127.2 0.0 1.4e-35 122.7 0.0 2.3 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KKK20169.1 - 6.8e-18 65.0 0.0 1.7e-17 63.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KKK20169.1 - 0.00014 21.9 0.0 0.0011 19.1 0.0 2.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KKK20169.1 - 0.0002 20.7 0.0 0.00039 19.7 0.0 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Alpha-2-MRAP_C PF06401.11 KKK20169.1 - 0.0011 19.0 1.3 0.0011 19.0 1.3 2.5 3 0 0 3 3 3 1 Alpha-2-macroglobulin RAP, C-terminal domain HDA2-3 PF11496.8 KKK20169.1 - 0.0046 16.2 0.0 0.018 14.2 0.0 1.7 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 SWI2_SNF2 PF18766.1 KKK20169.1 - 0.0049 16.6 0.1 2.7 7.6 0.0 2.8 2 0 0 2 2 2 2 SWI2/SNF2 ATPase SAM_1 PF00536.30 KKK20169.1 - 0.011 16.2 0.1 0.035 14.6 0.1 1.9 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) AAA_34 PF13872.6 KKK20169.1 - 0.035 13.0 0.0 0.1 11.4 0.0 1.7 1 1 0 1 1 1 0 P-loop containing NTP hydrolase pore-1 GDP_Man_Dehyd PF16363.5 KKK20175.1 - 3.1e-47 161.6 0.0 9e-47 160.1 0.0 1.7 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KKK20175.1 - 5e-46 157.1 0.0 7.6e-46 156.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KKK20175.1 - 7e-14 51.5 0.0 1.2e-13 50.7 0.0 1.4 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 KKK20175.1 - 1.3e-10 41.1 0.0 4e-10 39.5 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase Polysacc_synt_2 PF02719.15 KKK20175.1 - 3.6e-10 39.5 0.1 4.9e-09 35.7 0.1 2.2 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 KKK20175.1 - 5.6e-10 38.8 0.0 8e-10 38.3 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short_C2 PF13561.6 KKK20175.1 - 1.7e-05 24.5 0.1 3e-05 23.7 0.1 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 KKK20175.1 - 0.0011 18.9 0.0 0.0019 18.1 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding 3HCDH_N PF02737.18 KKK20175.1 - 0.079 12.8 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Cys_Met_Meta_PP PF01053.20 KKK20175.1 - 0.09 11.3 0.1 0.43 9.1 0.0 1.9 2 0 0 2 2 2 0 Cys/Met metabolism PLP-dependent enzyme UDPG_MGDP_dh_N PF03721.14 KKK20175.1 - 0.13 11.8 0.1 0.22 11.1 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain PAT1 PF09770.9 KKK20176.1 - 0 1186.0 0.7 0 1185.8 0.7 1.1 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Erf4 PF10256.9 KKK20176.1 - 0.13 12.4 0.0 1.5 8.9 0.0 2.4 2 0 0 2 2 2 0 Golgin subfamily A member 7/ERF4 family Glyco_transf_15 PF01793.16 KKK20177.1 - 9.1e-125 416.2 8.4 1.1e-124 415.9 8.4 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Ribosom_S12_S23 PF00164.25 KKK20178.1 - 8.2e-30 102.8 0.4 1.2e-29 102.2 0.4 1.2 1 0 0 1 1 1 1 Ribosomal protein S12/S23 UMP1 PF05348.11 KKK20179.1 - 1.8e-21 76.6 0.0 2.8e-21 75.9 0.0 1.2 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 Rad60-SLD_2 PF13881.6 KKK20180.1 - 4.6e-12 46.0 0.0 7.9e-12 45.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 KKK20180.1 - 0.0012 19.4 0.0 0.0024 18.4 0.0 1.5 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.23 KKK20180.1 - 0.034 13.9 0.0 0.061 13.1 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin family EXS PF03124.14 KKK20181.1 - 7.3e-101 337.8 33.2 9.6e-101 337.4 33.2 1.1 1 0 0 1 1 1 1 EXS family SPX PF03105.19 KKK20181.1 - 2e-75 255.1 12.3 2e-75 255.1 12.3 1.8 2 0 0 2 2 2 1 SPX domain BLI1 PF17324.2 KKK20181.1 - 0.094 13.4 0.5 0.21 12.2 0.5 1.5 1 0 0 1 1 1 0 BLOC-1 interactor 1 Stealth_CR2 PF11380.8 KKK20182.1 - 2.5e-35 120.9 2.1 3.5e-35 120.5 0.2 2.1 2 0 0 2 2 2 1 Stealth protein CR2, conserved region 2 Stealth_CR1 PF17101.5 KKK20182.1 - 1.8e-10 40.4 0.1 3.4e-10 39.5 0.1 1.4 1 0 0 1 1 1 1 Stealth protein CR1, conserved region 1 Stealth_CR3 PF17102.5 KKK20182.1 - 5.9e-09 35.7 0.2 1.2e-08 34.7 0.2 1.6 1 0 0 1 1 1 1 Stealth protein CR3, conserved region 3 Stealth_CR4 PF17103.5 KKK20182.1 - 0.0023 17.8 1.7 0.003 17.4 0.3 1.9 2 0 0 2 2 2 1 Stealth protein CR4, conserved region 4 Abhydrolase_3 PF07859.13 KKK20183.1 - 2.4e-35 122.3 0.1 2.4e-24 86.4 0.0 2.6 3 0 0 3 3 3 2 alpha/beta hydrolase fold CLN3 PF02487.17 KKK20184.1 - 1.9e-161 537.6 5.1 2.1e-161 537.4 5.1 1.0 1 0 0 1 1 1 1 CLN3 protein MFS_1 PF07690.16 KKK20184.1 - 0.00082 18.4 20.3 0.0028 16.7 17.3 2.4 1 1 0 1 1 1 1 Major Facilitator Superfamily HMGL-like PF00682.19 KKK20185.1 - 7.4e-47 160.1 0.1 9.4e-47 159.8 0.1 1.1 1 0 0 1 1 1 1 HMGL-like PE PF00934.20 KKK20185.1 - 0.11 12.8 3.0 0.21 11.9 0.2 2.3 2 0 0 2 2 2 0 PE family Diphthamide_syn PF01866.17 KKK20186.1 - 2.2e-116 388.6 0.0 2.7e-116 388.3 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein Bromodomain PF00439.25 KKK20187.1 - 2.1e-08 34.1 0.1 2.9e-05 24.0 0.0 3.1 3 0 0 3 3 3 2 Bromodomain ELYS PF13934.6 KKK20216.1 - 3.5e-67 226.6 1.1 4.3e-67 226.3 1.1 1.1 1 0 0 1 1 1 1 Nuclear pore complex assembly SMC_N PF02463.19 KKK20217.1 - 3e-79 265.5 0.0 5.8e-79 264.6 0.0 1.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KKK20217.1 - 1.6e-23 83.2 0.1 8e-23 81.0 0.0 2.3 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 KKK20217.1 - 2.6e-13 50.5 3.8 3.2e-06 27.2 0.0 4.0 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KKK20217.1 - 8.1e-05 22.3 0.0 0.00023 20.8 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain KASH_CCD PF14662.6 KKK20217.1 - 0.0061 16.4 22.5 0.0061 16.4 22.5 6.1 2 2 3 6 6 6 1 Coiled-coil region of CCDC155 or KASH Snapin_Pallidin PF14712.6 KKK20217.1 - 0.013 15.9 0.6 0.013 15.9 0.6 7.0 5 2 2 7 7 7 0 Snapin/Pallidin SbcCD_C PF13558.6 KKK20217.1 - 0.064 13.5 0.0 0.71 10.2 0.0 2.7 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit TMF_DNA_bd PF12329.8 KKK20217.1 - 0.19 11.7 0.0 0.19 11.7 0.0 10.7 7 3 3 10 10 10 0 TATA element modulatory factor 1 DNA binding ABC_tran PF00005.27 KKK20217.1 - 0.66 10.5 0.0 0.66 10.5 0.0 6.3 3 2 0 5 5 5 0 ABC transporter Spc7 PF08317.11 KKK20217.1 - 0.81 8.5 112.8 0.0096 14.8 11.4 7.2 2 2 4 7 7 7 0 Spc7 kinetochore protein Ribosomal_S10 PF00338.22 KKK20218.1 - 3.6e-25 88.0 0.2 4.3e-25 87.8 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e NupH_GANP PF16768.5 KKK20219.1 - 0.0058 16.4 27.9 0.0058 16.4 27.9 4.0 1 1 2 3 3 3 1 Nucleoporin homology of Germinal-centre associated nuclear protein DUF1657 PF07870.11 KKK20219.1 - 0.027 14.3 0.1 0.049 13.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1657) CUE PF02845.16 KKK20220.1 - 8.3e-06 25.4 0.0 2.3e-05 24.0 0.0 1.8 1 0 0 1 1 1 1 CUE domain Abhydrolase_3 PF07859.13 KKK20236.1 - 1.2e-48 165.8 0.1 1.8e-48 165.2 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KKK20236.1 - 2.5e-08 33.3 1.1 6.2e-08 32.0 1.1 1.5 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 KKK20236.1 - 0.095 12.2 0.2 4.8 6.6 0.1 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family adh_short PF00106.25 KKK20266.1 - 4.7e-14 52.3 1.2 1.1e-12 47.9 0.2 2.5 2 1 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KKK20266.1 - 9.1e-10 38.5 0.1 2.5e-08 33.8 0.1 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_6 PF08030.12 KKK20267.1 - 3.5e-20 72.7 0.0 6.6e-18 65.3 0.0 2.2 1 1 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 KKK20267.1 - 3.2e-17 62.8 1.7 3.2e-17 62.8 1.7 2.4 2 1 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KKK20267.1 - 5e-12 45.9 0.0 5.3e-08 32.9 0.0 2.3 2 0 0 2 2 2 2 FAD-binding domain DUF4405 PF14358.6 KKK20267.1 - 0.39 11.3 9.1 10 6.7 0.1 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4405) SF1-HH PF16275.5 KKK20269.1 - 1.6e-43 147.7 1.3 1.6e-43 147.7 1.3 1.8 2 0 0 2 2 2 1 Splicing factor 1 helix-hairpin domain GST_N PF02798.20 KKK20269.1 - 4.3e-13 49.4 0.0 8.1e-13 48.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KKK20269.1 - 4.5e-13 49.4 0.0 1.1e-12 48.1 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KKK20269.1 - 1.1e-11 44.8 0.0 3.7e-11 43.2 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KKK20269.1 - 1.3e-09 38.1 0.0 2.8e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KKK20269.1 - 2.4e-09 37.3 0.0 6.1e-09 36.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KKK20269.1 - 1.5e-07 31.3 0.1 2.8e-07 30.5 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain BCS1_N PF08740.11 KKK20270.1 - 2.3e-29 102.7 1.0 3.1e-29 102.3 1.0 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 KKK20270.1 - 1.3e-17 64.4 0.0 2.4e-16 60.4 0.0 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KKK20270.1 - 0.006 17.0 0.0 0.012 16.0 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 KKK20270.1 - 0.012 15.6 0.0 0.032 14.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF815 PF05673.13 KKK20270.1 - 0.019 14.2 0.0 0.046 12.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) RuvB_N PF05496.12 KKK20270.1 - 0.027 14.2 0.0 0.046 13.5 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain PPV_E1_C PF00519.17 KKK20270.1 - 0.037 12.9 0.0 0.064 12.1 0.0 1.3 1 0 0 1 1 1 0 Papillomavirus helicase AAA_18 PF13238.6 KKK20270.1 - 0.049 14.2 0.0 0.1 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.13 KKK20270.1 - 0.059 12.6 0.0 0.099 11.8 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain RNA_helicase PF00910.22 KKK20270.1 - 0.061 13.7 0.0 0.19 12.1 0.0 1.9 1 0 0 1 1 1 0 RNA helicase AAA_25 PF13481.6 KKK20270.1 - 0.091 12.3 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KKK20270.1 - 0.14 11.9 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_PrkA PF08298.11 KKK20270.1 - 0.24 10.3 0.0 0.37 9.7 0.0 1.2 1 0 0 1 1 1 0 PrkA AAA domain DUF3723 PF12520.8 KKK20271.1 - 2.2e-154 514.9 0.0 3.6e-152 507.6 0.0 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF3723) DUF1229 PF06797.11 KKK20280.1 - 0.037 14.2 0.7 0.037 14.2 0.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1229) EpuA PF11772.8 KKK20280.1 - 7.9 6.3 7.8 0.35 10.6 1.4 2.0 2 0 0 2 2 2 0 DNA-directed RNA polymerase subunit beta ANAPC10 PF03256.16 KKK20281.1 - 2.8e-41 141.2 0.0 5.9e-41 140.2 0.0 1.4 1 1 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) BSP_II PF05432.11 KKK20281.1 - 0.3 10.8 5.8 0.09 12.5 2.8 1.6 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) PTPRCAP PF15713.5 KKK20281.1 - 1.6 9.0 12.7 0.62 10.3 6.8 2.2 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated PS_Dcarbxylase PF02666.15 KKK20282.1 - 1.6e-79 266.1 0.0 4.1e-79 264.8 0.0 1.6 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase ubiquitin PF00240.23 KKK20283.1 - 9.3e-08 31.7 0.0 1.9e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family CCDC53 PF10152.9 KKK20283.1 - 2.8 8.3 8.3 0.92 9.9 4.3 2.2 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex Spore_coat_CotO PF14153.6 KKK20283.1 - 4.2 7.3 9.1 7.9 6.4 9.1 1.4 1 0 0 1 1 1 0 Spore coat protein CotO Sugar_tr PF00083.24 KKK20284.1 - 5.6e-49 167.2 8.1 1.5e-36 126.2 9.9 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KKK20284.1 - 0.00013 21.0 14.3 0.001 18.1 15.2 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Bax1-I PF01027.20 KKK20284.1 - 0.92 9.3 12.2 2.8 7.7 12.2 1.8 1 1 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 OPT PF03169.15 KKK20285.1 - 3.6e-27 95.3 6.1 4e-27 95.1 6.1 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein ECF_trnsprt PF12822.7 KKK20285.1 - 1.1 9.4 8.8 20 5.3 8.8 2.1 1 1 0 1 1 1 0 ECF transporter, substrate-specific component PGF-CTERM PF18204.1 KKK20285.1 - 3.7 7.7 7.0 17 5.5 0.3 2.8 2 0 0 2 2 2 0 PGF-CTERM motif FtsX PF02687.21 KKK20285.1 - 5.7 7.5 8.8 1.8 9.1 1.5 2.3 2 1 0 2 2 2 0 FtsX-like permease family Borrelia_REV PF03978.13 KKK20286.1 - 0.024 14.6 0.1 0.026 14.5 0.1 1.2 1 0 0 1 1 1 0 Borrelia burgdorferi REV protein DUF4349 PF14257.6 KKK20286.1 - 0.054 12.9 0.0 0.066 12.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) Arrestin_C PF02752.22 KKK20287.1 - 5.4e-19 69.0 0.0 9.7e-19 68.2 0.0 1.4 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 KKK20287.1 - 1.9e-11 44.2 0.0 3.2e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 KKK20287.1 - 0.0017 18.1 0.0 0.0042 16.8 0.0 1.6 2 0 0 2 2 2 1 Arrestin_N terminal like APH PF01636.23 KKK20288.1 - 8.6e-23 81.5 0.0 1.2e-22 81.1 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KKK20288.1 - 3.1e-06 26.9 0.0 5.2e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 KKK20288.1 - 0.011 15.3 0.0 0.074 12.7 0.0 2.0 2 0 0 2 2 2 0 RIO1 family EcKinase PF02958.20 KKK20288.1 - 0.19 11.0 0.0 0.29 10.4 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase EF_assoc_2 PF08356.12 KKK20289.1 - 1.5e-33 114.6 0.0 2.8e-33 113.7 0.0 1.5 1 0 0 1 1 1 1 EF hand associated EF_assoc_1 PF08355.12 KKK20289.1 - 1e-30 105.1 0.2 2e-30 104.2 0.2 1.5 1 0 0 1 1 1 1 EF hand associated Ras PF00071.22 KKK20289.1 - 6.7e-25 87.6 0.0 1.7e-13 50.5 0.0 2.3 2 0 0 2 2 2 2 Ras family Roc PF08477.13 KKK20289.1 - 8.1e-13 48.6 0.0 3.8e-07 30.3 0.0 3.5 4 1 1 5 5 2 2 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 KKK20289.1 - 4.5e-10 39.6 0.0 0.00059 19.9 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase ANAPC4_WD40 PF12894.7 KKK20289.1 - 5.2e-09 36.3 0.0 0.09 13.1 0.0 3.4 2 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KKK20289.1 - 1.1e-07 32.4 9.2 0.0029 18.4 0.2 5.5 5 0 0 5 5 5 1 WD domain, G-beta repeat EF-hand_1 PF00036.32 KKK20289.1 - 3.9e-05 22.9 1.2 0.057 13.0 0.1 2.7 2 0 0 2 2 2 2 EF hand AAA_16 PF13191.6 KKK20289.1 - 9.9e-05 22.8 0.2 0.75 10.2 0.0 2.9 2 0 0 2 2 2 2 AAA ATPase domain EF-hand_7 PF13499.6 KKK20289.1 - 0.00064 20.1 0.1 0.08 13.4 0.0 2.7 2 0 0 2 2 2 1 EF-hand domain pair Dynamin_N PF00350.23 KKK20289.1 - 0.00086 19.4 0.1 1.6 8.8 0.0 2.8 2 0 0 2 2 2 2 Dynamin family RsgA_GTPase PF03193.16 KKK20289.1 - 0.0012 18.8 0.2 4.6 7.1 0.0 3.4 3 0 0 3 3 3 1 RsgA GTPase EF-hand_8 PF13833.6 KKK20289.1 - 0.0015 18.3 0.3 0.4 10.6 0.0 2.6 2 0 0 2 2 2 1 EF-hand domain pair AAA_22 PF13401.6 KKK20289.1 - 0.0018 18.5 0.5 3.2 8.0 0.0 2.9 2 1 1 3 3 3 1 AAA domain EF-hand_6 PF13405.6 KKK20289.1 - 0.0019 18.0 0.9 0.38 10.8 0.1 2.8 2 0 0 2 2 2 1 EF-hand domain IKI3 PF04762.12 KKK20289.1 - 0.0025 15.9 0.0 0.0068 14.5 0.0 1.5 1 1 1 2 2 2 1 IKI3 family AAA_28 PF13521.6 KKK20289.1 - 0.0041 17.4 0.1 1.1 9.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KKK20289.1 - 0.0052 16.5 0.3 2.9 7.7 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain eIF2A PF08662.11 KKK20289.1 - 0.013 15.3 0.1 0.1 12.5 0.0 2.1 1 1 1 2 2 2 0 Eukaryotic translation initiation factor eIF2A RNA_helicase PF00910.22 KKK20289.1 - 0.017 15.5 0.0 2.5 8.5 0.0 2.7 2 0 0 2 2 2 0 RNA helicase ABC_tran PF00005.27 KKK20289.1 - 0.018 15.6 0.0 6.3 7.3 0.0 2.6 2 0 0 2 2 2 0 ABC transporter Zeta_toxin PF06414.12 KKK20289.1 - 0.02 14.2 0.1 4.5 6.5 0.0 2.7 3 0 0 3 3 3 0 Zeta toxin Viral_helicase1 PF01443.18 KKK20289.1 - 0.025 14.3 0.3 0.26 11.0 0.0 2.5 2 1 0 2 2 2 0 Viral (Superfamily 1) RNA helicase FtsK_SpoIIIE PF01580.18 KKK20289.1 - 0.052 12.9 0.2 3 7.1 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_7 PF12775.7 KKK20289.1 - 0.064 12.8 0.1 3.4 7.2 0.0 2.6 3 0 0 3 3 2 0 P-loop containing dynein motor region AAA_24 PF13479.6 KKK20289.1 - 0.064 13.0 0.2 0.63 9.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KKK20289.1 - 0.078 12.9 0.1 18 5.2 0.0 2.5 2 0 0 2 2 2 0 NACHT domain AAA_18 PF13238.6 KKK20289.1 - 0.079 13.5 0.0 3.4 8.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain Ploopntkinase3 PF18751.1 KKK20289.1 - 0.088 12.7 0.0 3.8 7.4 0.0 2.3 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 IIGP PF05049.13 KKK20289.1 - 0.13 11.3 0.3 0.88 8.6 0.0 2.0 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) Cytochrom_D1 PF02239.16 KKK20289.1 - 0.14 10.7 0.0 0.32 9.5 0.0 1.5 2 0 0 2 2 2 0 Cytochrome D1 heme domain Septin PF00735.18 KKK20289.1 - 0.15 11.3 0.0 2.2 7.5 0.0 2.2 2 0 0 2 2 2 0 Septin EF-hand_5 PF13202.6 KKK20289.1 - 0.21 11.2 2.8 1.8 8.2 0.2 2.5 2 0 0 2 2 2 0 EF hand DUF815 PF05673.13 KKK20289.1 - 0.23 10.6 0.1 4.5 6.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) EF-hand_10 PF14788.6 KKK20289.1 - 0.24 11.3 0.6 2.6 8.0 0.1 2.5 2 0 0 2 2 2 0 EF hand cobW PF02492.19 KKK20289.1 - 4.2 6.9 4.5 5.1 6.6 0.2 3.2 4 1 0 4 4 3 0 CobW/HypB/UreG, nucleotide-binding domain EMP24_GP25L PF01105.24 KKK20290.1 - 7.9e-42 143.2 0.0 9.6e-42 143.0 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD EzrA PF06160.12 KKK20290.1 - 0.031 12.4 0.4 0.04 12.1 0.4 1.0 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Zds_C PF08632.10 KKK20291.1 - 3.8e-28 97.0 1.2 6.7e-28 96.2 1.2 1.4 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term Ysc84 PF04366.12 KKK20292.1 - 7.7e-41 138.8 0.3 1.3e-40 138.1 0.3 1.4 1 0 0 1 1 1 1 Las17-binding protein actin regulator SH3_1 PF00018.28 KKK20292.1 - 2.1e-13 49.7 0.3 6.5e-13 48.1 0.2 1.9 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 KKK20292.1 - 1.3e-08 34.3 1.1 2.3e-08 33.6 0.1 1.9 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.6 KKK20292.1 - 1e-07 31.7 0.0 3.1e-07 30.1 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain DUF3104 PF11302.8 KKK20292.1 - 0.16 11.7 0.1 0.34 10.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3104) Prenyltransf PF01255.19 KKK20293.1 - 1.7e-79 266.5 0.0 3.7e-79 265.4 0.0 1.5 1 1 0 1 1 1 1 Putative undecaprenyl diphosphate synthase Sacchrp_dh_C PF16653.5 KKK20294.1 - 7.3e-85 285.3 0.0 1.3e-84 284.4 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain Sacchrp_dh_NADP PF03435.18 KKK20294.1 - 6e-25 88.0 0.8 9.5e-25 87.3 0.8 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 KKK20294.1 - 9.9e-09 35.4 0.2 1.7e-08 34.6 0.2 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.6 KKK20294.1 - 3.6e-05 23.7 0.4 0.0002 21.3 0.1 2.0 2 0 0 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 KKK20294.1 - 0.0014 18.2 0.3 0.002 17.7 0.3 1.2 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.19 KKK20294.1 - 0.0084 15.1 0.3 0.013 14.6 0.0 1.4 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 KKK20294.1 - 0.022 14.2 0.6 0.043 13.3 0.4 1.4 1 1 0 1 1 1 0 short chain dehydrogenase NAD_binding_7 PF13241.6 KKK20294.1 - 0.026 14.9 0.2 0.12 12.9 0.3 2.0 2 0 0 2 2 2 0 Putative NAD(P)-binding AlaDh_PNT_C PF01262.21 KKK20294.1 - 0.057 12.7 0.6 0.087 12.1 0.6 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain adh_short_C2 PF13561.6 KKK20294.1 - 0.1 12.1 0.3 0.18 11.3 0.3 1.4 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase COesterase PF00135.28 KKK20312.1 - 2.5e-09 36.5 0.2 3e-09 36.3 0.2 1.0 1 0 0 1 1 1 1 Carboxylesterase family Pkinase PF00069.25 KKK20313.1 - 2.1e-64 217.4 0.0 2.5e-64 217.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK20313.1 - 2.8e-36 125.2 0.0 3.7e-36 124.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KKK20313.1 - 1.9e-07 30.7 0.0 3e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KKK20313.1 - 8.1e-05 21.6 0.0 0.00012 21.0 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 KKK20313.1 - 0.0064 16.1 0.0 0.96 9.0 0.0 2.2 1 1 1 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 KKK20313.1 - 0.13 11.6 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 KKK20313.1 - 0.17 10.9 0.0 0.25 10.4 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 FAM75 PF14650.6 KKK20313.1 - 2.8 7.4 13.7 4.3 6.8 13.7 1.2 1 0 0 1 1 1 0 FAM75 family Sec39 PF08314.11 KKK20314.1 - 7.1e-263 874.5 0.0 8.1e-263 874.3 0.0 1.0 1 0 0 1 1 1 1 Secretory pathway protein Sec39 Ndufs5 PF10200.9 KKK20316.1 - 0.00083 19.6 0.1 0.0011 19.2 0.1 1.2 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa UPF0203 PF05254.12 KKK20316.1 - 0.0021 18.3 0.6 0.0032 17.7 0.6 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) DUF3128 PF11326.8 KKK20316.1 - 0.016 15.5 2.5 0.081 13.3 2.5 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3128) COX6B PF02297.17 KKK20316.1 - 0.021 15.0 0.2 0.036 14.3 0.2 1.4 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIb NYD-SP28_assoc PF14775.6 KKK20316.1 - 0.068 13.3 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 Sperm tail C-terminal domain LysM PF01476.20 KKK20317.1 - 4.5e-17 61.8 0.1 0.00017 21.6 0.0 4.6 5 0 0 5 5 5 4 LysM domain HAP2-GCS1 PF10699.9 KKK20317.1 - 0.0024 17.8 0.5 0.38 10.8 0.0 3.3 2 1 0 2 2 2 2 Male gamete fusion factor Exo_endo_phos PF03372.23 KKK20318.1 - 8.1e-08 32.1 0.2 1.7e-07 31.0 0.2 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family FSH1 PF03959.13 KKK20319.1 - 3.3e-24 85.8 0.0 3.8e-24 85.5 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 KKK20319.1 - 0.0055 16.5 0.1 0.011 15.5 0.1 1.5 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase MazG PF03819.17 KKK20319.1 - 0.058 13.6 0.3 0.65 10.2 0.0 2.2 2 0 0 2 2 2 0 MazG nucleotide pyrophosphohydrolase domain tRNA-synt_1c PF00749.21 KKK20320.1 - 1.6e-93 313.1 0.0 2.2e-93 312.6 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 KKK20320.1 - 2.2e-31 109.1 0.0 6.9e-31 107.4 0.0 1.9 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain NAD_binding_10 PF13460.6 KKK20321.1 - 0.0027 17.6 0.0 0.0043 17.0 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 KKK20321.1 - 0.0077 15.4 0.0 0.011 14.9 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 KKK20321.1 - 0.049 13.1 0.0 0.065 12.7 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 KKK20321.1 - 0.068 13.6 0.0 0.11 13.0 0.0 1.3 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Zn_clus PF00172.18 KKK20322.1 - 5.7e-08 32.8 7.5 1.1e-07 31.9 7.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KKK20322.1 - 8.6e-07 28.1 0.7 7.5e-06 25.0 0.7 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain Mac PF12464.8 KKK20323.1 - 6.7e-15 55.1 0.2 1.1e-14 54.4 0.2 1.3 1 0 0 1 1 1 1 Maltose acetyltransferase Hexapep PF00132.24 KKK20323.1 - 1.5e-12 46.7 13.8 1.6e-11 43.5 4.4 3.7 4 0 0 4 4 4 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KKK20323.1 - 1.9e-10 40.3 13.3 5.2e-10 38.9 4.6 3.2 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase Glyco_transf_54 PF04666.13 KKK20325.1 - 1.1e-10 40.8 0.0 1.4e-08 34.0 0.0 2.9 2 1 0 2 2 2 1 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region Abhydrolase_6 PF12697.7 KKK20325.1 - 1e-08 36.1 1.1 1e-08 36.1 1.1 3.4 2 1 0 3 3 3 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KKK20325.1 - 3.4e-06 26.5 0.0 4.1e-05 23.0 0.0 2.2 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KKK20325.1 - 0.00047 19.9 0.1 0.036 13.7 0.0 2.7 2 1 1 3 3 3 1 alpha/beta hydrolase fold Lipase_3 PF01764.25 KKK20325.1 - 0.0041 17.0 0.0 0.0077 16.1 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) DUF676 PF05057.14 KKK20325.1 - 0.0087 15.6 0.0 0.014 14.9 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_2 PF02230.16 KKK20325.1 - 0.038 13.8 0.0 9.9 5.9 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase DUF1749 PF08538.10 KKK20325.1 - 0.081 12.0 0.0 0.17 11.0 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1749) Epimerase PF01370.21 KKK20326.1 - 0.0062 16.0 0.0 0.087 12.3 0.0 2.3 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 KKK20326.1 - 0.0078 15.4 0.0 0.16 11.1 0.0 2.2 2 0 0 2 2 2 1 Male sterility protein Polysacc_synt_2 PF02719.15 KKK20326.1 - 0.031 13.4 0.1 0.14 11.2 0.0 1.9 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Semialdhyde_dh PF01118.24 KKK20326.1 - 0.04 14.3 0.0 0.072 13.5 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 KKK20326.1 - 0.12 12.5 0.0 0.25 11.5 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus p450 PF00067.22 KKK20327.1 - 3.8e-45 154.5 0.0 2.1e-44 152.1 0.0 1.8 2 0 0 2 2 2 1 Cytochrome P450 GtrA PF04138.14 KKK20327.1 - 0.33 11.2 5.7 0.81 9.9 5.7 1.6 1 0 0 1 1 1 0 GtrA-like protein Zn_clus PF00172.18 KKK20328.1 - 2.4e-06 27.5 9.0 5.5e-06 26.4 9.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KKK20328.1 - 2.9e-06 26.3 0.1 4.8e-06 25.6 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain MIT PF04212.18 KKK20328.1 - 0.044 13.8 0.0 1.5 8.9 0.0 2.7 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain DUF5056 PF16479.5 KKK20328.1 - 0.1 12.9 0.1 0.23 11.7 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5056) MFS_1 PF07690.16 KKK20329.1 - 9.7e-47 159.6 27.4 9.7e-47 159.6 27.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KKK20329.1 - 4.9e-11 42.2 10.4 4.9e-11 42.2 10.4 2.6 2 1 0 3 3 3 2 Sugar (and other) transporter MFS_4 PF06779.14 KKK20329.1 - 2e-05 24.1 13.7 4e-05 23.1 5.3 2.9 3 0 0 3 3 3 2 Uncharacterised MFS-type transporter YbfB OATP PF03137.20 KKK20329.1 - 0.17 10.1 12.8 0.27 9.5 2.1 3.1 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family G_glu_transpept PF01019.21 KKK20330.1 - 1.7e-142 475.8 0.0 1.9e-142 475.6 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase zf-C2H2 PF00096.26 KKK20332.1 - 3.7e-07 30.2 10.9 0.00031 21.0 1.7 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KKK20332.1 - 0.00063 20.4 8.8 0.044 14.6 1.0 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger FOXP-CC PF16159.5 KKK20332.1 - 0.52 11.0 4.5 2.2 9.0 0.4 2.3 1 1 1 2 2 2 0 FOXP coiled-coil domain CHORD PF04968.12 KKK20332.1 - 0.92 10.3 5.0 12 6.7 0.6 2.5 1 1 1 2 2 2 0 CHORD zf-CGNR PF11706.8 KKK20332.1 - 1.2 9.1 4.9 0.7 9.8 0.9 2.3 2 0 0 2 2 2 0 CGNR zinc finger CactinC_cactus PF09732.9 KKK20333.1 - 7.5e-45 151.9 1.9 1.6e-44 150.8 1.9 1.6 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein Cactin_mid PF10312.9 KKK20333.1 - 5.1e-22 78.6 0.6 1.1e-21 77.4 0.6 1.6 1 0 0 1 1 1 1 Conserved mid region of cactin Forkhead PF00250.18 KKK20333.1 - 3.6e-21 75.2 0.0 8.4e-21 74.0 0.0 1.6 1 0 0 1 1 1 1 Forkhead domain DUF1087 PF06465.13 KKK20333.1 - 0.014 15.4 3.2 0.082 12.9 0.3 2.7 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1087) HEAT_2 PF13646.6 KKK20334.1 - 4.9e-07 30.1 7.9 5.1e-05 23.6 0.8 5.3 4 1 1 5 5 5 2 HEAT repeats HEAT PF02985.22 KKK20334.1 - 8.3e-07 28.8 9.0 0.011 16.0 0.0 6.1 6 0 0 6 6 6 2 HEAT repeat Cnd1 PF12717.7 KKK20334.1 - 1.9e-06 28.0 1.2 0.98 9.4 0.0 5.3 4 2 2 6 6 6 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 KKK20334.1 - 0.00041 20.8 5.3 0.027 15.0 0.1 4.8 4 0 0 4 4 4 1 HEAT-like repeat RIX1 PF08167.12 KKK20334.1 - 0.0092 15.7 0.3 3.5 7.3 0.0 4.0 5 0 0 5 5 5 1 rRNA processing/ribosome biogenesis Nipped-B_C PF12830.7 KKK20334.1 - 0.018 15.0 1.0 0.14 12.1 0.0 2.9 4 1 0 4 4 4 0 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.7 KKK20334.1 - 0.037 14.3 2.6 1.1 9.7 0.0 4.0 4 0 0 4 4 4 0 HEAT repeat associated with sister chromatid cohesion CLASP_N PF12348.8 KKK20334.1 - 0.038 13.6 0.3 1.9 8.0 0.1 3.1 2 1 1 3 3 3 0 CLASP N terminal MFS_1 PF07690.16 KKK20335.1 - 3.1e-39 134.9 37.5 3.1e-39 134.9 37.5 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KKK20335.1 - 2e-11 43.5 7.9 2e-11 43.5 7.9 2.1 3 0 0 3 3 3 1 Sugar (and other) transporter PHD PF00628.29 KKK20336.1 - 1.5e-09 37.6 13.2 5.4e-09 35.8 5.8 2.6 2 0 0 2 2 2 1 PHD-finger zf-RING_2 PF13639.6 KKK20336.1 - 3.5e-09 36.8 0.7 3.5e-09 36.8 0.7 3.2 3 0 0 3 3 3 1 Ring finger domain zf-rbx1 PF12678.7 KKK20336.1 - 6.9e-07 29.5 0.3 6.9e-07 29.5 0.3 2.6 2 0 0 2 2 2 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 KKK20336.1 - 1.2e-06 28.2 0.9 1.2e-06 28.2 0.9 2.5 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 KKK20336.1 - 3.8e-06 26.7 0.1 3.8e-06 26.7 0.1 2.8 4 0 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KKK20336.1 - 4.3e-06 26.5 1.5 4.3e-06 26.5 1.5 2.6 4 0 0 4 4 2 1 Zinc finger, C3HC4 type (RING finger) PHD_2 PF13831.6 KKK20336.1 - 1.6e-05 24.4 1.8 1.6e-05 24.4 1.8 1.7 2 0 0 2 2 1 1 PHD-finger zf-RING_5 PF14634.6 KKK20336.1 - 1.9e-05 24.5 0.3 1.9e-05 24.5 0.3 3.0 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KKK20336.1 - 4.8e-05 23.1 0.6 4.8e-05 23.1 0.6 3.2 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 KKK20336.1 - 0.0019 17.8 0.4 0.0019 17.8 0.4 2.4 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-RING_UBOX PF13445.6 KKK20336.1 - 0.0032 17.5 1.5 0.0032 17.5 1.5 3.2 3 1 1 4 4 3 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 KKK20336.1 - 0.0042 17.1 0.0 0.0042 17.1 0.0 1.8 2 0 0 2 2 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zinc_ribbon_16 PF17034.5 KKK20336.1 - 0.03 14.6 0.1 0.07 13.3 0.1 1.6 1 0 0 1 1 1 0 Zinc-ribbon like family Rtf2 PF04641.12 KKK20336.1 - 0.065 12.6 0.0 0.065 12.6 0.0 1.9 2 0 0 2 2 2 0 Rtf2 RING-finger zf-RING_4 PF14570.6 KKK20336.1 - 0.11 12.3 0.1 0.11 12.3 0.1 2.4 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_11 PF17123.5 KKK20336.1 - 0.3 10.9 0.0 0.3 10.9 0.0 3.5 4 0 0 4 4 4 0 RING-like zinc finger DZR PF12773.7 KKK20336.1 - 0.54 10.3 5.5 1.3e+02 2.7 5.5 2.9 1 1 0 1 1 1 0 Double zinc ribbon Prok-RING_1 PF14446.6 KKK20336.1 - 0.67 9.9 8.4 0.92 9.5 2.0 3.1 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 zf-C2HC_2 PF13913.6 KKK20336.1 - 1.3 9.1 4.9 0.88 9.5 0.5 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type RecR PF02132.15 KKK20336.1 - 1.3 8.7 7.6 3.5 7.3 1.2 3.3 3 0 0 3 3 3 0 RecR protein zf-RING_9 PF13901.6 KKK20336.1 - 5.2 7.0 7.9 8 6.4 0.3 2.5 2 1 0 2 2 2 0 Putative zinc-RING and/or ribbon Alg6_Alg8 PF03155.15 KKK20337.1 - 3.1e-172 573.9 28.1 3.6e-172 573.7 28.1 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family Lectin_leg-like PF03388.13 KKK20338.1 - 1e-26 93.8 0.0 1.6e-26 93.1 0.0 1.2 1 0 0 1 1 1 1 Legume-like lectin family SesA PF17107.5 KKK20338.1 - 0.017 15.3 1.1 0.042 14.0 1.1 1.6 1 1 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases FAM196 PF15265.6 KKK20338.1 - 0.04 13.4 2.6 0.049 13.1 2.6 1.1 1 0 0 1 1 1 0 FAM196 family EMP24_GP25L PF01105.24 KKK20338.1 - 0.096 12.6 1.9 0.21 11.5 1.9 1.6 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD ABC_tran_CTD PF16326.5 KKK20338.1 - 0.12 12.7 1.0 0.43 10.9 1.0 1.9 1 1 0 1 1 1 0 ABC transporter C-terminal domain DUF3232 PF11554.8 KKK20338.1 - 0.13 12.7 0.1 0.23 11.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3232) YmgB PF10798.8 KKK20338.1 - 0.28 11.0 1.1 0.65 9.9 1.1 1.6 1 0 0 1 1 1 0 Biofilm development protein YmgB/AriR DUF4349 PF14257.6 KKK20338.1 - 0.49 9.8 9.0 12 5.3 9.0 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4349) SNF5 PF04855.12 KKK20339.1 - 3.1e-66 223.6 0.3 1.9e-65 221.0 0.3 2.0 1 1 0 1 1 1 1 SNF5 / SMARCB1 / INI1 Exo_endo_phos PF03372.23 KKK20340.1 - 0.00023 20.8 0.1 0.00092 18.8 0.1 1.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family HNH_2 PF13391.6 KKK20340.1 - 0.1 12.8 0.1 2 8.6 0.0 2.4 2 0 0 2 2 2 0 HNH endonuclease Peptidase_M24 PF00557.24 KKK20341.1 - 3.8e-09 36.6 0.1 6.3e-09 35.8 0.1 1.4 1 1 0 1 1 1 1 Metallopeptidase family M24 PHD PF00628.29 KKK20342.1 - 1.3e-19 69.9 18.2 7.2e-12 45.0 6.8 2.5 2 0 0 2 2 2 2 PHD-finger PHD_2 PF13831.6 KKK20342.1 - 0.047 13.2 17.8 0.04 13.5 1.4 3.7 4 0 0 4 4 4 0 PHD-finger C1_1 PF00130.22 KKK20342.1 - 0.083 12.8 14.0 0.069 13.0 2.6 2.5 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-PHD-like PF15446.6 KKK20342.1 - 0.23 11.1 15.4 0.17 11.5 2.7 3.0 3 0 0 3 3 3 0 PHD/FYVE-zinc-finger like domain zf-RanBP PF00641.18 KKK20342.1 - 0.39 10.1 4.2 0.21 10.9 0.6 2.3 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others zf-HC5HC2H_2 PF13832.6 KKK20342.1 - 2.1 8.5 6.9 12 6.0 0.6 2.4 2 0 0 2 2 2 0 PHD-zinc-finger like domain Ribosomal_L37ae PF01780.19 KKK20343.1 - 4.4e-41 138.9 10.2 5.1e-41 138.7 10.2 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family zf-RING_13 PF17977.1 KKK20343.1 - 0.0017 18.4 1.9 0.0025 17.9 1.9 1.3 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Zn_Tnp_IS1595 PF12760.7 KKK20343.1 - 0.0075 16.2 2.9 0.013 15.5 2.9 1.4 1 0 0 1 1 1 1 Transposase zinc-ribbon domain A2L_zn_ribbon PF08792.10 KKK20343.1 - 0.021 14.5 3.1 0.58 9.9 0.1 2.2 2 0 0 2 2 2 0 A2L zinc ribbon domain DUF1451 PF07295.11 KKK20343.1 - 0.024 14.7 0.8 0.034 14.2 0.8 1.2 1 0 0 1 1 1 0 Zinc-ribbon containing domain Zn-ribbon_8 PF09723.10 KKK20343.1 - 0.09 12.9 0.6 0.19 11.9 0.6 1.5 1 0 0 1 1 1 0 Zinc ribbon domain zf-BED PF02892.15 KKK20343.1 - 0.16 12.0 4.6 1.6 8.8 0.4 2.3 1 1 1 2 2 2 0 BED zinc finger CarbpepA_inh PF02977.15 KKK20343.1 - 0.58 10.0 4.5 6.1 6.7 4.5 2.1 1 1 0 1 1 1 0 Carboxypeptidase A inhibitor zf-H2C2_2 PF13465.6 KKK20343.1 - 1.4 9.5 5.2 3.5 8.2 0.6 2.3 1 1 1 2 2 2 0 Zinc-finger double domain Sacchrp_dh_NADP PF03435.18 KKK20344.1 - 3.5e-16 59.7 0.0 5.4e-16 59.0 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 KKK20344.1 - 0.15 12.5 0.0 1.3 9.5 0.0 2.3 2 1 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Abhydrolase_1 PF00561.20 KKK20345.1 - 5.7e-21 75.3 0.2 5e-20 72.2 0.2 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KKK20345.1 - 6.3e-16 59.6 0.0 9.2e-16 59.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KKK20345.1 - 1.4e-10 40.8 0.0 1.3e-09 37.7 0.0 1.9 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Ndr PF03096.14 KKK20345.1 - 0.03 13.0 0.0 0.044 12.5 0.0 1.2 1 0 0 1 1 1 0 Ndr family Paf1 PF03985.13 KKK20345.1 - 0.17 10.8 0.0 0.23 10.4 0.0 1.2 1 0 0 1 1 1 0 Paf1 Pinin_SDK_memA PF04696.13 KKK20346.1 - 1.3e-30 106.1 12.4 1.3e-30 106.1 12.4 2.6 3 0 0 3 3 3 1 pinin/SDK/memA/ protein conserved region SR-25 PF10500.9 KKK20346.1 - 1.6 8.3 23.9 0.09 12.4 15.2 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Apolipoprotein PF01442.18 KKK20364.1 - 0.00028 20.8 1.0 0.00054 19.9 1.0 1.4 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain ATP-synt_B PF00430.18 KKK20364.1 - 0.011 15.8 0.9 0.022 14.8 0.9 1.4 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) REF PF05755.12 KKK20364.1 - 0.057 13.2 0.1 0.099 12.5 0.1 1.3 1 0 0 1 1 1 0 Rubber elongation factor protein (REF) DUF883 PF05957.13 KKK20364.1 - 0.09 13.4 0.5 0.24 12.0 0.5 1.8 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) Rhabdo_M1 PF03342.13 KKK20364.1 - 0.23 10.8 2.0 0.43 9.9 2.0 1.4 1 0 0 1 1 1 0 Rhabdovirus M1 matrix protein (M1 polymerase-associated protein) LsmAD PF06741.13 KKK20364.1 - 0.31 11.6 3.4 0.79 10.3 3.4 1.7 1 0 0 1 1 1 0 LsmAD domain Cdh1_DBD_1 PF18196.1 KKK20364.1 - 0.35 11.2 3.3 0.77 10.1 3.3 1.7 1 1 0 1 1 1 0 Chromodomain helicase DNA-binding domain 1 Iwr1 PF08574.10 KKK20365.1 - 1.6e-20 73.8 7.4 1.6e-20 73.8 7.4 2.8 3 0 0 3 3 3 1 Transcription factor Iwr1 RRM_1 PF00076.22 KKK20366.1 - 3.5e-37 126.0 0.0 5.6e-12 45.3 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KKK20366.1 - 2.8e-13 49.5 0.0 0.0032 17.3 0.0 4.3 4 0 0 4 4 4 3 Occluded RNA-recognition motif RRM PF10378.9 KKK20366.1 - 2e-08 33.8 2.3 1.3e-07 31.2 2.3 2.5 1 0 0 1 1 1 1 Putative RRM domain DUF4523 PF15023.6 KKK20366.1 - 2.8e-05 24.0 0.0 0.47 10.3 0.0 3.0 3 0 0 3 3 3 2 Protein of unknown function (DUF4523) RRM_7 PF16367.5 KKK20366.1 - 0.00047 20.2 0.0 0.23 11.6 0.0 3.3 3 0 0 3 3 3 1 RNA recognition motif RRM_3 PF08777.11 KKK20366.1 - 0.0013 18.7 0.1 0.72 9.9 0.1 2.9 3 0 0 3 3 3 2 RNA binding motif RNA_bind PF08675.11 KKK20366.1 - 0.21 11.6 0.2 1.6 8.8 0.0 2.5 3 0 0 3 3 3 0 RNA binding domain PB1 PF00564.24 KKK20385.1 - 2.8e-09 36.8 0.1 5.6e-09 35.8 0.1 1.5 1 0 0 1 1 1 1 PB1 domain PH_10 PF15411.6 KKK20385.1 - 2.1e-08 34.5 0.0 5.4e-08 33.1 0.0 1.7 2 0 0 2 2 2 1 Pleckstrin homology domain GCIP PF13324.6 KKK20386.1 - 0.068 12.8 0.2 0.11 12.1 0.2 1.3 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting EVI2A PF05399.11 KKK20386.1 - 8.1 6.0 7.4 13 5.3 7.4 1.3 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) MFS_1 PF07690.16 KKK20387.1 - 2.6e-31 108.9 37.9 4.1e-18 65.4 5.0 3.0 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KKK20387.1 - 6e-05 22.1 10.5 6e-05 22.1 10.5 3.1 2 1 0 2 2 2 1 Sugar (and other) transporter Phasin PF05597.11 KKK20388.1 - 0.062 13.3 0.4 0.15 12.0 0.4 1.7 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Pyridoxal_deC PF00282.19 KKK20389.1 - 4.5e-73 246.1 0.0 5.7e-73 245.8 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain OKR_DC_1 PF01276.20 KKK20389.1 - 0.09 11.5 0.0 0.13 11.0 0.0 1.3 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain Glyco_hydro_71 PF03659.14 KKK20390.1 - 1.1e-137 458.8 6.2 1.6e-137 458.3 6.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 WD40 PF00400.32 KKK20391.1 - 1.5e-13 50.9 0.3 0.73 10.8 0.1 7.0 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKK20391.1 - 7.6e-07 29.4 0.0 0.085 13.2 0.0 4.5 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Lactonase PF10282.9 KKK20391.1 - 0.036 13.3 0.0 0.056 12.7 0.0 1.2 1 0 0 1 1 1 0 Lactonase, 7-bladed beta-propeller Cyclin_N PF00134.23 KKK20392.1 - 4.6e-36 123.4 0.1 1e-35 122.3 0.1 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KKK20392.1 - 4.4e-11 42.9 0.1 9e-11 41.9 0.1 1.5 1 0 0 1 1 1 1 Cyclin, C-terminal domain UvrD_C PF13361.6 KKK20394.1 - 1.5e-62 212.0 0.0 2.9e-59 201.2 0.0 2.3 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.21 KKK20394.1 - 7.9e-55 186.6 0.2 7.4e-35 121.0 0.3 2.5 1 1 1 2 2 2 2 UvrD/REP helicase N-terminal domain AAA_19 PF13245.6 KKK20394.1 - 1.8e-29 103.0 0.0 4.4e-29 101.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 KKK20394.1 - 3.6e-14 52.3 0.0 1.1e-13 50.8 0.0 1.9 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.6 KKK20394.1 - 2.2e-08 34.1 0.0 1.2e-06 28.4 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_12 PF13087.6 KKK20394.1 - 7.3e-05 22.5 0.0 0.0039 16.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 KKK20394.1 - 0.00052 19.8 0.3 0.52 10.0 0.0 3.2 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_11 PF13086.6 KKK20394.1 - 0.0062 16.4 0.3 0.019 14.7 0.3 2.0 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KKK20394.1 - 0.05 13.9 1.3 7.8 6.8 1.3 2.5 1 1 0 1 1 1 0 AAA domain Cyt-b5 PF00173.28 KKK20395.1 - 3.6e-14 52.7 0.0 5.3e-14 52.1 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Zip PF02535.22 KKK20396.1 - 2.3e-64 217.7 5.2 2.8e-64 217.4 5.2 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter DUF4702 PF15774.5 KKK20397.1 - 0.0061 15.6 1.0 0.008 15.2 1.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4702) Saw1 PF11561.8 KKK20397.1 - 0.025 14.1 0.3 0.1 12.1 0.2 1.9 2 0 0 2 2 2 0 Single strand annealing-weakened 1 MRI PF15325.6 KKK20397.1 - 0.16 13.1 2.9 0.27 12.3 2.6 1.5 1 1 0 1 1 1 0 Modulator of retrovirus infection Draxin PF15550.6 KKK20397.1 - 3.4 7.4 8.0 1.1 9.1 5.0 1.6 1 1 1 2 2 2 0 Draxin Rpr2 PF04032.16 KKK20414.1 - 4.8e-25 87.7 1.0 4.8e-25 87.7 1.0 1.7 2 0 0 2 2 2 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain DZR PF12773.7 KKK20414.1 - 0.26 11.3 3.3 1.5 8.9 3.3 2.2 1 1 0 1 1 1 0 Double zinc ribbon DUF2897 PF11446.8 KKK20414.1 - 0.93 9.4 3.8 1.7 8.6 3.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) T3SSipB PF16535.5 KKK20415.1 - 0.015 15.8 0.3 0.03 14.8 0.3 1.5 1 0 0 1 1 1 0 Type III cell invasion protein SipB DUF1664 PF07889.12 KKK20415.1 - 0.034 14.2 1.9 0.2 11.7 1.9 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.10 KKK20415.1 - 0.038 14.2 2.9 0.1 12.8 2.9 1.6 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Pox_A_type_inc PF04508.12 KKK20415.1 - 0.041 13.7 3.5 0.47 10.4 0.1 3.2 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat Fzo_mitofusin PF04799.13 KKK20415.1 - 0.043 13.4 0.7 0.086 12.4 0.7 1.5 1 1 0 1 1 1 0 fzo-like conserved region Baculo_PEP_C PF04513.12 KKK20415.1 - 0.045 13.8 2.5 1.5 8.8 1.3 2.1 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.12 KKK20415.1 - 0.067 13.7 2.2 3 8.4 2.2 2.5 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein HSCB_C PF07743.13 KKK20415.1 - 0.11 13.0 2.9 1.1 9.8 0.5 2.3 1 1 1 2 2 2 0 HSCB C-terminal oligomerisation domain DUF1640 PF07798.11 KKK20415.1 - 0.12 12.4 3.4 0.47 10.5 3.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1640) Nbl1_Borealin_N PF10444.9 KKK20415.1 - 0.16 11.6 5.1 0.28 10.8 1.1 2.5 2 0 0 2 2 2 0 Nbl1 / Borealin N terminal NAP PF00956.18 KKK20415.1 - 0.18 10.9 0.2 0.22 10.7 0.2 1.1 1 0 0 1 1 1 0 Nucleosome assembly protein (NAP) Utp12 PF04003.12 KKK20415.1 - 0.77 10.1 3.3 0.76 10.1 1.8 1.9 2 1 0 2 2 2 0 Dip2/Utp12 Family DEAD PF00270.29 KKK20416.1 - 1.8e-37 128.8 0.0 3.4e-37 127.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KKK20416.1 - 1.8e-25 89.4 0.0 7.3e-24 84.3 0.1 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KKK20416.1 - 1.6e-07 31.5 0.0 3.3e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 KKK20416.1 - 0.011 15.0 0.1 0.051 12.9 0.0 1.9 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit CcmD PF04995.14 KKK20418.1 - 0.86 9.7 3.2 0.76 9.9 1.2 1.9 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) SMC_N PF02463.19 KKK20419.1 - 5.1e-60 202.6 0.0 1.3e-58 198.1 0.0 2.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KKK20419.1 - 1.2e-30 106.2 1.6 2.3e-30 105.3 0.0 2.4 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 KKK20419.1 - 4.1e-11 43.2 14.1 3e-06 27.3 0.4 4.0 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KKK20419.1 - 3.7e-08 33.0 0.0 7.8e-08 31.9 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 KKK20419.1 - 2.2e-06 27.7 8.5 2.2e-06 27.7 8.5 4.5 2 2 1 3 3 1 1 AAA ATPase domain SbcCD_C PF13558.6 KKK20419.1 - 0.003 17.8 0.1 0.042 14.1 0.0 3.0 3 0 0 3 3 3 1 Putative exonuclease SbcCD, C subunit DUF1664 PF07889.12 KKK20419.1 - 0.0036 17.3 3.5 0.0036 17.3 3.5 8.1 5 2 4 9 9 9 1 Protein of unknown function (DUF1664) DUF948 PF06103.11 KKK20419.1 - 0.013 15.7 26.3 0.38 11.0 1.6 6.9 5 2 1 6 6 6 0 Bacterial protein of unknown function (DUF948) AAA_23 PF13476.6 KKK20419.1 - 0.036 14.6 109.8 0.41 11.1 1.0 6.7 3 2 1 4 4 2 0 AAA domain SRCR_2 PF15494.6 KKK20419.1 - 3.1 8.4 8.4 0.5 10.9 0.8 3.2 2 1 0 2 2 2 0 Scavenger receptor cysteine-rich domain Mce4_CUP1 PF11887.8 KKK20419.1 - 3.3 7.1 5.8 1.8 8.0 0.3 2.7 3 0 0 3 3 3 0 Cholesterol uptake porter CUP1 of Mce4, putative E3_binding PF02817.17 KKK20420.1 - 7.3e-10 39.0 0.1 7.5e-08 32.6 0.0 2.8 2 0 0 2 2 2 2 e3 binding domain B12-binding PF02310.19 KKK20421.1 - 0.00025 21.1 0.0 0.00036 20.6 0.0 1.2 1 0 0 1 1 1 1 B12 binding domain FtsK_SpoIIIE PF01580.18 KKK20421.1 - 0.033 13.5 0.0 0.033 13.5 0.0 1.1 1 0 0 1 1 1 0 FtsK/SpoIIIE family GalP_UDP_transf PF01087.22 KKK20422.1 - 2e-69 233.7 0.0 1.1e-67 228.0 0.0 2.3 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.17 KKK20422.1 - 4.1e-58 195.8 0.3 1.1e-57 194.4 0.3 1.6 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, C-terminal domain DUF4921 PF16268.5 KKK20422.1 - 0.0029 16.5 0.1 0.28 9.9 0.0 2.6 2 1 0 3 3 3 2 Domain of unknown function (DUF4921) Erg28 PF03694.13 KKK20423.1 - 9e-34 116.2 0.7 1.1e-33 115.9 0.7 1.1 1 0 0 1 1 1 1 Erg28 like protein NAD_binding_2 PF03446.15 KKK20424.1 - 3.5e-11 43.5 0.2 1.2e-09 38.5 0.2 2.5 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 KKK20424.1 - 6.1e-09 36.2 0.1 2.1e-08 34.4 0.0 2.0 2 0 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase UDPGT PF00201.18 KKK20424.1 - 5.2e-08 32.1 0.0 8.9e-08 31.4 0.0 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Shikimate_DH PF01488.20 KKK20424.1 - 0.03 14.4 0.1 0.084 12.9 0.1 1.7 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase XPC-binding PF09280.11 KKK20424.1 - 0.2 11.4 0.0 0.5 10.1 0.0 1.6 1 0 0 1 1 1 0 XPC-binding domain F-box-like PF12937.7 KKK20425.1 - 5.7e-07 29.3 0.4 1.3e-06 28.2 0.4 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KKK20425.1 - 0.003 17.4 0.5 0.0064 16.3 0.5 1.6 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 KKK20425.1 - 0.0052 16.7 0.2 0.0094 15.8 0.2 1.3 1 0 0 1 1 1 1 F-box CbeA_antitoxin PF06154.11 KKK20425.1 - 0.17 12.5 0.0 0.34 11.5 0.0 1.5 1 0 0 1 1 1 0 CbeA_antitoxin, type IV, cytoskeleton bundling-enhancing factor A adh_short PF00106.25 KKK20426.1 - 2.6e-37 128.2 0.0 4e-37 127.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KKK20426.1 - 4.1e-24 85.4 0.0 5.3e-24 85.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KKK20426.1 - 0.00022 21.2 0.0 0.00041 20.3 0.0 1.5 1 1 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 KKK20426.1 - 0.047 13.6 0.0 0.067 13.1 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Sugar_tr PF00083.24 KKK20427.1 - 3.6e-97 326.1 14.3 4.3e-97 325.8 14.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKK20427.1 - 3.7e-19 68.9 20.8 4.4e-19 68.6 20.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF2530 PF10745.9 KKK20427.1 - 0.0095 16.2 1.9 0.0095 16.2 1.9 2.5 1 1 1 2 2 2 1 Protein of unknown function (DUF2530) DUF4293 PF14126.6 KKK20427.1 - 1.2 9.4 5.7 0.28 11.4 0.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4293) AcetylCoA_hyd_C PF13336.6 KKK20428.1 - 1.2e-05 25.2 0.0 1.7e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain DUF2249 PF10006.9 KKK20428.1 - 0.084 12.8 1.1 2.6 8.0 0.0 2.3 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2249) HD PF01966.22 KKK20429.1 - 3.8e-05 23.9 0.0 5.3e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 HD domain HDOD PF08668.12 KKK20429.1 - 0.0065 16.0 0.0 0.0089 15.5 0.0 1.2 1 0 0 1 1 1 1 HDOD domain Peptidase_M35 PF02102.15 KKK20430.1 - 3.1e-164 546.1 13.0 4.1e-164 545.7 13.0 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.6 KKK20430.1 - 2.1e-44 151.6 4.7 3.9e-44 150.7 4.7 1.4 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase HRXXH PF13933.6 KKK20430.1 - 0.0073 15.9 2.0 0.014 15.0 2.0 1.4 1 1 0 1 1 1 1 Putative peptidase family CARDB PF07705.11 KKK20430.1 - 0.22 11.8 3.6 0.47 10.8 0.4 2.9 2 2 1 3 3 3 0 CARDB Tmemb_14 PF03647.13 KKK20431.1 - 3.1e-12 47.1 3.0 4.1e-12 46.7 3.0 1.1 1 0 0 1 1 1 1 Transmembrane proteins 14C DUF2339 PF10101.9 KKK20431.1 - 0.0083 14.8 2.4 0.0094 14.6 2.4 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2339) DUF2530 PF10745.9 KKK20431.1 - 0.29 11.4 2.3 1.7 8.9 0.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2530) PEP_mutase PF13714.6 KKK20432.1 - 2.4e-34 118.9 0.2 2.7e-34 118.7 0.2 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 KKK20432.1 - 3.7e-17 62.0 0.0 4.1e-17 61.9 0.0 1.1 1 0 0 1 1 1 1 Isocitrate lyase family Glyco_hydro_17 PF00332.18 KKK20433.1 - 1.3e-07 31.6 1.1 2.3e-07 30.7 1.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 HTH_6 PF01418.17 KKK20433.1 - 0.055 13.4 0.0 0.28 11.2 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain, rpiR family PQQ PF01011.21 KKK20433.1 - 0.12 12.4 0.5 0.29 11.1 0.5 1.7 1 0 0 1 1 1 0 PQQ enzyme repeat DUF4667 PF15700.5 KKK20433.1 - 0.85 9.7 9.2 1.5 8.9 9.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4667) SPX PF03105.19 KKK20433.1 - 1.3 8.8 4.3 2.1 8.2 4.3 1.3 1 0 0 1 1 1 0 SPX domain FR47 PF08445.10 KKK20434.1 - 1.3e-05 25.0 0.0 2.2e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_1 PF00583.25 KKK20434.1 - 3.1e-05 24.2 0.0 4.4e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KKK20434.1 - 8e-05 22.6 0.2 0.00015 21.7 0.2 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KKK20434.1 - 0.00064 20.1 0.1 0.00099 19.5 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KKK20434.1 - 0.0036 17.4 0.0 0.013 15.6 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain GNAT_acetyltran PF12746.7 KKK20434.1 - 0.014 15.0 0.0 0.02 14.5 0.0 1.1 1 0 0 1 1 1 0 GNAT acetyltransferase SCA7 PF08313.12 KKK20457.1 - 3.4e-31 106.9 1.1 1e-30 105.4 1.1 1.9 1 0 0 1 1 1 1 SCA7, zinc-binding domain OrsD PF12013.8 KKK20457.1 - 0.022 15.2 1.1 0.12 12.8 0.1 2.4 2 0 0 2 2 2 0 Orsellinic acid/F9775 biosynthesis cluster protein D Cut8 PF08559.10 KKK20457.1 - 0.026 14.1 1.9 0.048 13.3 1.9 1.4 1 0 0 1 1 1 0 Cut8, nuclear proteasome tether protein CDC45 PF02724.14 KKK20457.1 - 0.32 9.2 10.3 0.41 8.9 10.3 1.2 1 0 0 1 1 1 0 CDC45-like protein Ketoacyl-synt_C PF02801.22 KKK20458.1 - 2.2e-33 114.8 1.4 2.8e-33 114.4 1.4 1.1 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_C PF02803.18 KKK20458.1 - 0.013 15.2 0.5 0.02 14.6 0.5 1.4 1 0 0 1 1 1 0 Thiolase, C-terminal domain mRNA_cap_enzyme PF01331.19 KKK20459.1 - 3.5e-52 177.1 0.2 4.5e-52 176.7 0.2 1.2 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.15 KKK20459.1 - 6.1e-33 113.7 0.0 1.3e-32 112.6 0.0 1.6 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.21 KKK20459.1 - 1.8e-08 34.3 0.2 4.6e-07 29.7 0.1 2.3 1 1 1 2 2 2 1 ATP dependent DNA ligase domain RNA_ligase PF09414.10 KKK20459.1 - 0.0006 20.2 0.1 0.0014 18.9 0.0 1.6 2 0 0 2 2 2 1 RNA ligase ECH_2 PF16113.5 KKK20460.1 - 1.7e-129 432.1 0.0 2.3e-129 431.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 KKK20460.1 - 8.1e-25 87.6 0.0 1.7e-24 86.6 0.0 1.5 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase PBP PF01161.20 KKK20461.1 - 1.7e-08 34.9 0.0 3e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Ribosomal_L4 PF00573.22 KKK20462.1 - 3.3e-44 150.9 0.0 3.9e-44 150.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family FA_hydroxylase PF04116.13 KKK20463.1 - 7.1e-25 87.9 15.8 7.1e-25 87.9 15.8 2.2 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily bVLRF1 PF18826.1 KKK20463.1 - 0.16 11.8 0.1 0.28 11.0 0.1 1.3 1 0 0 1 1 1 0 bacteroidetes VLRF1 release factor OGG_N PF07934.12 KKK20464.1 - 2.9e-37 127.4 0.1 7.1e-37 126.2 0.0 1.7 2 0 0 2 2 2 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.25 KKK20464.1 - 2.6e-13 50.4 0.0 3.9e-13 49.8 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein FMO-like PF00743.19 KKK20465.1 - 1.6e-13 50.0 0.0 1.4e-12 46.8 0.0 2.4 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KKK20465.1 - 2.6e-11 43.3 0.0 5.5e-06 25.8 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KKK20465.1 - 2.5e-09 36.9 0.0 2.5e-05 23.7 0.0 3.1 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KKK20465.1 - 3.9e-09 36.1 0.1 2.9e-05 23.4 0.0 3.2 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KKK20465.1 - 4.7e-09 36.4 0.0 1.1e-08 35.2 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KKK20465.1 - 6.8e-06 25.9 0.0 0.11 12.0 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KKK20465.1 - 0.00022 21.2 0.0 1 9.3 0.0 2.7 2 0 0 2 2 2 2 FAD-NAD(P)-binding Thi4 PF01946.17 KKK20465.1 - 0.0036 16.6 0.1 0.049 12.9 0.0 2.2 2 0 0 2 2 2 1 Thi4 family GIDA PF01134.22 KKK20465.1 - 0.017 14.2 0.0 0.43 9.6 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_binding_2 PF00890.24 KKK20465.1 - 0.065 12.3 0.0 2.5 7.1 0.0 2.4 2 0 0 2 2 2 0 FAD binding domain DUF2914 PF11141.8 KKK20465.1 - 0.082 12.7 0.0 0.2 11.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2914) HI0933_like PF03486.14 KKK20465.1 - 0.18 10.4 0.0 14 4.3 0.0 2.2 2 0 0 2 2 2 0 HI0933-like protein VRR_NUC PF08774.11 KKK20466.1 - 5.1e-24 84.4 0.0 2.6e-23 82.2 0.0 2.3 1 0 0 1 1 1 1 VRR-NUC domain BNIP2 PF12496.8 KKK20466.1 - 6.6 7.2 8.0 20 5.6 8.0 1.8 1 0 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 Ribosomal_S13_N PF08069.12 KKK20467.1 - 4.7e-29 100.2 0.1 7.7e-29 99.5 0.1 1.4 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 KKK20467.1 - 4.9e-15 55.5 0.3 7.1e-15 55.0 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein S15 PAX PF00292.18 KKK20467.1 - 0.021 14.7 0.1 0.051 13.5 0.0 1.7 2 0 0 2 2 2 0 'Paired box' domain YflT PF11181.8 KKK20467.1 - 0.11 13.0 0.0 0.16 12.5 0.0 1.3 1 0 0 1 1 1 0 Heat induced stress protein YflT 7tm_2 PF00002.24 KKK20468.1 - 2.8e-06 26.8 22.0 8.5e-06 25.2 16.5 2.0 1 1 0 2 2 2 2 7 transmembrane receptor (Secretin family) Dicty_CAR PF05462.11 KKK20468.1 - 0.018 14.2 19.7 0.062 12.4 10.4 2.7 2 1 0 2 2 2 0 Slime mold cyclic AMP receptor DUF212 PF02681.14 KKK20468.1 - 3.6 7.7 5.7 1.7 8.8 2.2 2.0 2 0 0 2 2 2 0 Divergent PAP2 family RRM_1 PF00076.22 KKK20469.1 - 2.6e-27 94.4 0.0 5.7e-11 42.1 0.0 3.7 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KKK20469.1 - 0.004 17.0 0.0 2.4 8.1 0.0 3.2 3 0 0 3 3 3 2 Occluded RNA-recognition motif Dpy-30 PF05186.13 KKK20470.1 - 0.00045 19.8 0.0 0.00056 19.5 0.0 1.1 1 0 0 1 1 1 1 Dpy-30 motif PP1_bind PF15276.6 KKK20470.1 - 0.016 15.5 0.2 0.042 14.2 0.1 1.8 1 1 1 2 2 2 0 Protein phosphatase 1 binding Ribosomal_S27e PF01667.17 KKK20483.1 - 0.046 13.4 0.9 0.1 12.3 0.1 1.9 2 0 0 2 2 2 0 Ribosomal protein S27 EphA2_TM PF14575.6 KKK20483.1 - 0.18 12.7 0.0 0.46 11.4 0.0 1.9 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Ephrin_rec_like PF07699.13 KKK20483.1 - 0.55 10.0 5.5 3.1 7.6 1.2 2.7 2 0 0 2 2 2 0 Putative ephrin-receptor like Sas10_Utp3 PF04000.15 KKK20529.1 - 5.4e-16 59.0 0.2 5.4e-16 59.0 0.2 2.0 2 0 0 2 2 2 1 Sas10/Utp3/C1D family PCI PF01399.27 KKK20530.1 - 0.035 14.6 0.0 10 6.7 0.0 2.9 3 0 0 3 3 3 0 PCI domain 5_nucleotid_C PF02872.18 KKK20531.1 - 3e-38 131.5 0.0 5e-38 130.8 0.0 1.3 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 KKK20531.1 - 0.00027 21.5 0.5 0.001 19.6 0.0 2.1 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase His_Phos_1 PF00300.22 KKK20532.1 - 0.00097 18.9 0.1 2.2 7.9 0.0 3.2 3 0 0 3 3 3 3 Histidine phosphatase superfamily (branch 1) EMP70 PF02990.16 KKK20533.1 - 1.3e-201 670.8 1.3 1.6e-201 670.5 1.3 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 NAD_binding_8 PF13450.6 KKK20534.1 - 5e-06 26.7 0.0 7e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.19 KKK20534.1 - 1.7e-05 23.5 0.0 2.1e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like 3HCDH_N PF02737.18 KKK20534.1 - 0.00033 20.6 0.1 0.00043 20.2 0.1 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DAO PF01266.24 KKK20534.1 - 0.00051 19.7 0.3 0.00062 19.5 0.3 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 KKK20534.1 - 0.00076 18.8 0.1 0.001 18.4 0.1 1.1 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_2 PF07992.14 KKK20534.1 - 0.00091 18.5 0.0 0.0011 18.2 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KKK20534.1 - 0.0066 16.4 0.1 0.011 15.8 0.1 1.3 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 KKK20534.1 - 0.0072 16.9 0.4 0.01 16.4 0.4 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KKK20534.1 - 0.01 15.0 0.3 0.012 14.7 0.3 1.1 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.6 KKK20534.1 - 0.051 12.8 0.0 0.068 12.4 0.0 1.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KKK20534.1 - 0.074 11.7 0.1 0.095 11.4 0.1 1.1 1 0 0 1 1 1 0 HI0933-like protein GIDA PF01134.22 KKK20534.1 - 0.14 11.3 0.2 0.15 11.1 0.2 1.1 1 0 0 1 1 1 0 Glucose inhibited division protein A FAD_binding_3 PF01494.19 KKK20534.1 - 0.19 10.9 0.1 0.23 10.7 0.1 1.1 1 0 0 1 1 1 0 FAD binding domain Mst1_SARAH PF11629.8 KKK20544.1 - 0.067 13.3 0.1 0.14 12.3 0.1 1.5 1 0 0 1 1 1 0 C terminal SARAH domain of Mst1 G-patch PF01585.23 KKK20545.1 - 4.5e-12 45.7 1.2 9.1e-12 44.7 1.2 1.6 1 0 0 1 1 1 1 G-patch domain zf-RanBP PF00641.18 KKK20545.1 - 3e-10 39.2 1.9 7.2e-10 38.0 1.9 1.7 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others RRM_1 PF00076.22 KKK20545.1 - 1.4e-08 34.5 4.0 0.00017 21.3 0.0 3.2 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) G-patch_2 PF12656.7 KKK20545.1 - 7.5e-05 22.7 1.3 0.00023 21.2 1.3 1.9 1 0 0 1 1 1 1 G-patch domain RED_N PF07808.13 KKK20545.1 - 0.17 11.5 0.0 0.17 11.5 0.0 2.8 3 0 0 3 3 3 0 RED-like protein N-terminal region NCD3G PF07562.14 KKK20545.1 - 3.5 7.7 7.1 5.8 7.0 1.6 2.4 2 0 0 2 2 2 0 Nine Cysteines Domain of family 3 GPCR Zn_clus PF00172.18 KKK20546.1 - 4.6e-08 33.0 11.3 1e-07 31.9 11.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gpr1_Fun34_YaaH PF01184.19 KKK20547.1 - 5.6e-27 94.7 14.2 7.1e-27 94.4 14.2 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family FxsA PF04186.13 KKK20547.1 - 1.1 9.5 8.1 3.4 7.8 0.2 2.4 2 1 0 2 2 2 0 FxsA cytoplasmic membrane protein Pex24p PF06398.11 KKK20547.1 - 5.3 5.9 4.4 1.1 8.1 1.2 1.5 2 0 0 2 2 2 0 Integral peroxisomal membrane peroxin Pectate_lyase_3 PF12708.7 KKK20548.1 - 2e-64 217.4 16.3 3.7e-55 187.1 1.0 3.2 3 1 1 4 4 4 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 KKK20548.1 - 0.013 15.2 0.1 0.046 13.4 0.0 2.0 2 0 0 2 2 2 0 N terminal extension of bacteriophage endosialidase DUF3433 PF11915.8 KKK20549.1 - 2.1e-34 117.8 15.9 3.1e-23 82.1 4.3 3.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3433) Zn_clus PF00172.18 KKK20550.1 - 2.8e-08 33.7 8.8 4.9e-08 33.0 8.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KKK20550.1 - 4.3e-08 32.4 0.8 2.1e-07 30.1 0.4 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Peptidase_C14 PF00656.22 KKK20551.1 - 1.4e-20 74.3 0.0 2e-20 73.8 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Prp19 PF08606.11 KKK20551.1 - 0.13 12.2 0.1 0.34 10.9 0.1 1.7 1 0 0 1 1 1 0 Prp19/Pso4-like CHAT PF12770.7 KKK20552.1 - 4.8e-64 216.5 0.4 9.6e-64 215.6 0.4 1.4 1 0 0 1 1 1 1 CHAT domain TPR_12 PF13424.6 KKK20552.1 - 1e-06 28.9 5.2 3.3 8.0 0.0 5.9 5 2 0 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.28 KKK20552.1 - 0.00043 20.0 7.1 8.1 6.5 0.0 6.0 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_MalT PF17874.1 KKK20552.1 - 0.0029 17.0 4.1 0.74 9.1 0.0 4.4 4 1 0 5 5 5 1 MalT-like TPR region TPR_8 PF13181.6 KKK20552.1 - 0.022 15.0 4.3 4 7.9 0.0 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.17 KKK20552.1 - 0.11 12.6 10.1 36 4.8 0.0 6.5 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_7 PF13176.6 KKK20552.1 - 0.95 9.7 5.0 25 5.2 0.1 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat MIT PF04212.18 KKK20552.1 - 0.96 9.6 4.3 3.5 7.8 0.0 3.1 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_14 PF13428.6 KKK20552.1 - 9.7 7.3 10.8 8.5 7.5 0.0 6.1 6 0 0 6 6 6 0 Tetratricopeptide repeat Pyr_redox_3 PF13738.6 KKK20553.1 - 1.4e-17 63.9 0.0 2.1e-15 56.8 0.0 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KKK20553.1 - 3.2e-14 52.8 0.0 8.3e-13 48.2 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KKK20553.1 - 3.6e-14 52.1 0.2 3.3e-12 45.6 0.0 2.4 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 KKK20553.1 - 2e-08 33.8 0.0 2.2e-06 27.1 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KKK20553.1 - 2.4e-06 27.7 0.0 4e-05 23.8 0.0 3.0 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 KKK20553.1 - 1.9e-05 24.1 0.2 6.3e-05 22.4 0.1 1.9 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 KKK20553.1 - 0.00034 21.1 0.5 0.79 10.3 0.0 2.8 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KKK20553.1 - 0.0045 16.1 1.2 0.0075 15.4 1.2 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KKK20553.1 - 0.0059 15.4 0.3 0.015 14.0 0.1 1.7 2 0 0 2 2 2 1 HI0933-like protein 2-Hacid_dh_C PF02826.19 KKK20553.1 - 0.018 14.4 0.1 0.12 11.7 0.0 2.1 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GIDA PF01134.22 KKK20553.1 - 0.026 13.6 0.8 0.28 10.2 0.4 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A Shikimate_DH PF01488.20 KKK20553.1 - 0.038 14.0 0.1 13 5.9 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Thi4 PF01946.17 KKK20553.1 - 0.062 12.5 0.0 1 8.5 0.0 2.2 2 0 0 2 2 2 0 Thi4 family AlaDh_PNT_C PF01262.21 KKK20553.1 - 0.079 12.2 0.2 0.18 11.1 0.2 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DUF4176 PF13780.6 KKK20553.1 - 0.11 12.6 0.1 0.26 11.3 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4176) IlvN PF07991.12 KKK20553.1 - 0.14 11.7 0.2 9 5.8 0.0 2.3 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain ADH_N PF08240.12 KKK20554.1 - 2.6e-30 104.5 3.0 5.5e-30 103.5 3.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KKK20554.1 - 3.1e-23 82.2 0.2 7.4e-23 81.0 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KKK20554.1 - 9.9e-10 39.6 0.0 2.1e-09 38.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KKK20554.1 - 0.003 16.9 0.1 0.0064 15.8 0.1 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_2 PF07992.14 KKK20554.1 - 0.1 11.8 0.1 0.15 11.2 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KKK20566.1 - 6e-13 48.8 0.5 1e-12 48.0 0.5 1.3 1 1 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 KKK20566.1 - 3.3e-05 24.3 0.2 0.00025 21.5 0.2 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KKK20566.1 - 0.00023 20.9 0.6 0.0028 17.3 0.1 2.1 1 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KKK20566.1 - 0.00037 19.8 0.1 0.0053 16.0 0.0 2.0 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase CoA_transf_3 PF02515.17 KKK20566.1 - 0.001 18.2 0.4 0.002 17.3 0.0 1.6 2 0 0 2 2 2 1 CoA-transferase family III NAD_binding_8 PF13450.6 KKK20566.1 - 0.0013 18.9 0.0 0.0029 17.8 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 KKK20566.1 - 0.011 15.2 0.3 0.02 14.3 0.3 1.6 1 1 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KKK20566.1 - 0.028 13.5 0.0 0.064 12.3 0.0 1.6 1 0 0 1 1 1 0 FAD binding domain AlaDh_PNT_C PF01262.21 KKK20566.1 - 0.03 13.6 0.3 0.047 13.0 0.3 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ApbA PF02558.16 KKK20566.1 - 0.035 13.7 0.1 0.061 13.0 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox_3 PF13738.6 KKK20566.1 - 0.049 12.9 0.0 0.16 11.2 0.1 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KKK20566.1 - 0.074 12.3 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 Thi4 family GIDA PF01134.22 KKK20566.1 - 0.08 12.0 0.2 0.13 11.3 0.2 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A MutS_V PF00488.21 KKK20567.1 - 9.3e-81 270.4 0.1 1.6e-80 269.6 0.1 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KKK20567.1 - 3e-39 135.3 1.6 7.2e-39 134.0 1.6 1.7 1 0 0 1 1 1 1 MutS domain III MutS_II PF05188.17 KKK20567.1 - 4e-20 72.5 0.4 3.5e-19 69.4 0.0 2.7 3 0 0 3 3 3 1 MutS domain II MutS_IV PF05190.18 KKK20567.1 - 2.3e-17 63.1 0.9 7e-17 61.6 0.9 1.9 1 0 0 1 1 1 1 MutS family domain IV MutS_I PF01624.20 KKK20567.1 - 1.4e-14 54.3 0.0 1e-13 51.5 0.0 2.3 2 0 0 2 2 2 1 MutS domain I SUR7 PF06687.12 KKK20567.1 - 0.11 12.1 0.0 0.35 10.5 0.1 1.8 2 0 0 2 2 2 0 SUR7/PalI family CDT1_C PF16679.5 KKK20568.1 - 5.1e-20 71.7 0.0 1.1e-19 70.6 0.0 1.6 1 0 0 1 1 1 1 DNA replication factor Cdt1 C-terminal domain Lentiviral_Tat PF02998.14 KKK20568.1 - 0.016 15.3 0.2 0.1 12.7 0.1 2.2 2 0 0 2 2 2 0 Lentiviral Tat protein Pox_Ag35 PF03286.14 KKK20568.1 - 0.026 14.3 3.5 0.043 13.6 3.5 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein MPP6 PF10175.9 KKK20568.1 - 0.039 14.4 1.3 0.077 13.5 1.3 1.4 1 0 0 1 1 1 0 M-phase phosphoprotein 6 CPSF100_C PF13299.6 KKK20568.1 - 0.07 13.3 0.7 0.16 12.1 0.7 1.6 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal PBP1_TM PF14812.6 KKK20568.1 - 0.077 13.4 3.0 0.19 12.1 3.0 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nop14 PF04147.12 KKK20568.1 - 0.1 10.8 3.5 0.14 10.3 3.5 1.1 1 0 0 1 1 1 0 Nop14-like family Sporozoite_P67 PF05642.11 KKK20568.1 - 0.13 10.3 5.8 0.22 9.6 5.8 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CENP-B_dimeris PF09026.10 KKK20568.1 - 0.36 11.2 9.4 0.72 10.3 9.4 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain FAM176 PF14851.6 KKK20568.1 - 0.41 10.3 3.6 0.78 9.4 3.6 1.4 1 0 0 1 1 1 0 FAM176 family TRAP_alpha PF03896.16 KKK20568.1 - 0.71 9.0 2.4 1.5 8.0 2.4 1.5 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit NOA36 PF06524.12 KKK20568.1 - 0.75 9.1 4.2 1.2 8.4 4.2 1.2 1 0 0 1 1 1 0 NOA36 protein CDC45 PF02724.14 KKK20568.1 - 3.1 6.0 5.0 4.6 5.4 5.0 1.1 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 KKK20568.1 - 3.5 5.6 7.2 5.4 5.0 7.2 1.2 1 0 0 1 1 1 0 DNA polymerase phi Gpi1 PF05024.15 KKK20569.1 - 4.1e-77 258.5 8.7 4.1e-77 258.5 8.7 1.8 2 0 0 2 2 2 1 N-acetylglucosaminyl transferase component (Gpi1) Aldedh PF00171.22 KKK20570.1 - 3.7e-187 622.5 0.3 4.2e-187 622.3 0.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Exo84_C PF16528.5 KKK20571.1 - 1.4e-69 234.0 0.2 1.4e-69 234.0 0.2 1.9 2 0 0 2 2 2 1 Exocyst component 84 C-terminal Vps51 PF08700.11 KKK20571.1 - 4.1e-18 65.3 2.0 1.1e-17 63.8 2.0 1.8 1 0 0 1 1 1 1 Vps51/Vps67 Tub PF01167.18 KKK20571.1 - 0.23 11.2 1.4 0.27 11.0 0.3 1.5 2 0 0 2 2 2 0 Tub family HIP1_clath_bdg PF16515.5 KKK20571.1 - 3.2 8.4 8.4 0.39 11.4 2.5 2.4 3 0 0 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 F-box-like PF12937.7 KKK20572.1 - 4.3e-10 39.3 0.2 8.9e-10 38.3 0.2 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KKK20572.1 - 1.7e-09 37.3 0.8 4.5e-09 36.0 0.3 2.0 2 0 0 2 2 2 1 F-box domain F-box_4 PF15966.5 KKK20572.1 - 0.0087 15.9 0.0 0.019 14.9 0.0 1.5 1 0 0 1 1 1 1 F-box DUF2014 PF09427.10 KKK20572.1 - 0.13 11.6 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2014) UIM PF02809.20 KKK20572.1 - 6.6 6.9 5.3 24 5.2 0.1 3.3 3 0 0 3 3 3 0 Ubiquitin interaction motif Mre11_DNA_bind PF04152.14 KKK20573.1 - 5.9e-56 189.4 0.8 5.9e-56 189.4 0.8 2.3 3 0 0 3 3 3 1 Mre11 DNA-binding presumed domain Metallophos PF00149.28 KKK20573.1 - 2.6e-13 50.9 2.1 6.7e-13 49.6 1.7 1.8 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KKK20573.1 - 0.00069 19.8 0.0 0.0063 16.7 0.0 2.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain FmdE PF02663.14 KKK20573.1 - 0.19 11.8 1.7 0.28 11.2 0.2 2.2 2 0 0 2 2 2 0 FmdE, Molybdenum formylmethanofuran dehydrogenase operon MAS20 PF02064.15 KKK20574.1 - 2.2e-41 141.0 1.0 2.1e-27 95.8 0.3 2.0 2 0 0 2 2 2 2 MAS20 protein import receptor betaPIX_CC PF16523.5 KKK20574.1 - 0.0058 16.4 0.8 0.0093 15.8 0.8 1.3 1 0 0 1 1 1 1 betaPIX coiled coil PhoU PF01895.19 KKK20574.1 - 0.14 12.6 0.2 0.29 11.6 0.2 1.5 1 0 0 1 1 1 0 PhoU domain Glyco_hydro_72 PF03198.14 KKK20575.1 - 2.8e-120 401.3 1.3 4.6e-118 394.1 1.3 2.1 1 1 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.18 KKK20575.1 - 6.4e-05 22.5 0.2 0.01 15.3 0.0 2.3 2 0 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Phage_Gp17 PF17549.2 KKK20575.1 - 0.13 12.3 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 Gene Product 17 RAP1 PF07218.11 KKK20575.1 - 3.8 5.7 10.1 4.3 5.5 6.8 2.1 2 0 0 2 2 2 0 Rhoptry-associated protein 1 (RAP-1) DUF676 PF05057.14 KKK20591.1 - 0.073 12.6 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Hydrolase_4 PF12146.8 KKK20591.1 - 0.08 12.2 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 LCAT PF02450.15 KKK20591.1 - 0.097 11.8 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Peptidase_S9 PF00326.21 KKK20591.1 - 0.25 10.8 0.0 0.42 10.0 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family ADH_N PF08240.12 KKK20592.1 - 1.5e-28 98.8 0.1 1.8e-28 98.6 0.1 1.1 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Ribosomal_L22 PF00237.19 KKK20593.1 - 7.1e-11 42.3 0.1 8.5e-11 42.0 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e 2-Hacid_dh_C PF02826.19 KKK20594.1 - 1.8e-55 187.1 0.0 2.3e-55 186.7 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KKK20594.1 - 3e-19 69.0 0.0 3.7e-19 68.7 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KKK20594.1 - 0.00031 20.9 0.2 0.0027 17.9 0.1 2.1 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase HSF_DNA-bind PF00447.17 KKK20646.1 - 8.7e-32 109.6 1.8 2e-31 108.4 1.8 1.6 1 0 0 1 1 1 1 HSF-type DNA-binding Response_reg PF00072.24 KKK20646.1 - 2.2e-17 63.2 0.0 5.1e-17 62.1 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain SlyX PF04102.12 KKK20646.1 - 0.19 12.4 7.5 0.14 12.8 5.0 2.2 2 0 0 2 2 2 0 SlyX DivIC PF04977.15 KKK20646.1 - 0.32 10.8 1.8 0.69 9.7 1.8 1.5 1 0 0 1 1 1 0 Septum formation initiator W2 PF02020.18 KKK20647.1 - 5e-18 65.0 8.3 5e-18 65.0 8.3 2.8 2 1 1 3 3 3 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.24 KKK20647.1 - 2.1e-10 39.9 11.9 0.00021 20.8 0.9 3.9 1 1 3 4 4 4 4 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.23 KKK20647.1 - 8.3e-06 25.6 0.0 1.7e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep_2 PF14602.6 KKK20647.1 - 5e-05 23.0 11.7 0.089 12.6 0.3 4.1 1 1 3 4 4 4 3 Hexapeptide repeat of succinyl-transferase NTP_transf_3 PF12804.7 KKK20647.1 - 0.0063 16.9 0.0 0.015 15.7 0.0 1.7 1 0 0 1 1 1 1 MobA-like NTP transferase domain DUF4954 PF16314.5 KKK20647.1 - 0.036 12.2 0.9 0.11 10.6 0.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4954) RVT_connect PF06815.13 KKK20647.1 - 0.084 13.1 0.0 0.28 11.4 0.0 1.9 1 0 0 1 1 1 0 Reverse transcriptase connection domain Keratin_assoc PF09775.9 KKK20647.1 - 0.092 12.4 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Keratinocyte-associated protein 2 Peptidase_U57 PF05582.12 KKK20647.1 - 0.092 12.0 0.7 0.18 11.0 0.7 1.4 1 0 0 1 1 1 0 YabG peptidase U57 Lipoprotein_10 PF03202.13 KKK20647.1 - 0.54 10.7 3.2 0.98 9.9 0.8 2.4 2 0 0 2 2 2 0 Putative mycoplasma lipoprotein, C-terminal region Band_7 PF01145.25 KKK20650.1 - 5.9e-31 107.8 0.7 1.4e-30 106.6 0.7 1.6 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_C PF16200.5 KKK20650.1 - 1.8e-23 82.3 1.3 1.8e-23 82.3 1.3 2.0 2 0 0 2 2 2 1 C-terminal region of band_7 Pox_A11 PF05061.13 KKK20650.1 - 0.085 12.1 0.2 0.12 11.6 0.2 1.2 1 0 0 1 1 1 0 Poxvirus A11 Protein Band_7_1 PF13421.6 KKK20650.1 - 0.096 12.4 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 SPFH domain-Band 7 family GSH-S_N PF02951.14 KKK20650.1 - 0.11 12.6 0.1 0.53 10.4 0.1 2.1 2 1 0 2 2 2 0 Prokaryotic glutathione synthetase, N-terminal domain NPR3 PF03666.13 KKK20651.1 - 1.9e-156 521.5 3.3 1.5e-154 515.2 0.0 2.1 2 0 0 2 2 2 2 Nitrogen Permease regulator of amino acid transport activity 3 YchF-GTPase_C PF06071.13 KKK20652.1 - 1.3e-21 76.5 0.0 3.9e-21 75.0 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 KKK20652.1 - 4.5e-17 62.2 0.0 1.2e-16 60.8 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KKK20652.1 - 0.00018 21.0 0.0 0.00037 20.0 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B AAA_14 PF13173.6 KKK20652.1 - 0.049 13.7 0.0 0.16 12.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 KKK20652.1 - 0.14 12.2 0.1 6.7 6.7 0.0 2.7 1 1 1 3 3 3 0 Dynamin family Hira PF07569.11 KKK20653.1 - 1.3e-84 283.4 0.0 2.6e-84 282.4 0.0 1.5 1 0 0 1 1 1 1 TUP1-like enhancer of split WD40 PF00400.32 KKK20653.1 - 2.7e-25 88.1 18.6 4.2e-05 24.2 0.0 9.3 9 1 0 9 9 9 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKK20653.1 - 3.6e-11 43.2 0.0 0.063 13.6 0.0 5.2 3 1 3 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain HIRA_B PF09453.10 KKK20653.1 - 1.5e-10 40.7 0.1 3.4e-10 39.5 0.1 1.7 1 0 0 1 1 1 1 HIRA B motif PD40 PF07676.12 KKK20653.1 - 1.1e-05 25.2 2.0 0.44 10.5 0.0 5.3 5 0 0 5 5 5 2 WD40-like Beta Propeller Repeat IKI3 PF04762.12 KKK20653.1 - 0.11 10.4 0.1 0.36 8.8 0.0 1.7 2 0 0 2 2 2 0 IKI3 family Methyltransf_7 PF03492.15 KKK20695.1 - 3.8e-25 88.8 0.0 2.9e-15 56.3 0.0 2.1 2 0 0 2 2 2 2 SAM dependent carboxyl methyltransferase Zn_clus PF00172.18 KKK20696.1 - 1.3e-10 41.2 9.8 2.4e-10 40.4 9.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KKK20696.1 - 0.12 11.4 0.0 0.2 10.6 0.0 1.4 1 0 0 1 1 1 0 Fungal specific transcription factor domain FMN_dh PF01070.18 KKK20697.1 - 2.1e-114 382.2 0.2 2.4e-114 382.0 0.2 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 KKK20697.1 - 6.8e-07 28.7 0.0 1.2e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 KKK20697.1 - 0.00013 21.1 0.1 0.00043 19.4 0.0 1.8 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 KKK20697.1 - 0.00086 18.8 0.4 0.0015 17.9 0.2 1.4 2 0 0 2 2 2 1 Nitronate monooxygenase His_biosynth PF00977.21 KKK20697.1 - 0.027 13.9 0.5 1 8.7 0.1 2.3 1 1 1 2 2 2 0 Histidine biosynthesis protein ThiG PF05690.14 KKK20697.1 - 0.091 12.0 0.0 10 5.3 0.0 2.3 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG Pkinase PF00069.25 KKK20700.1 - 6.9e-17 61.7 0.0 7.2e-16 58.3 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK20700.1 - 0.00039 19.8 0.0 0.00057 19.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Metallophos PF00149.28 KKK20701.1 - 4.2e-14 53.5 1.5 7.1e-14 52.8 1.5 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PI-PLC-X PF00388.19 KKK20703.1 - 3.8e-05 23.3 0.0 5.9e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain DUF4043 PF13252.6 KKK20703.1 - 0.046 12.9 0.0 0.075 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4043) His_Phos_2 PF00328.22 KKK20704.1 - 3.9e-05 23.2 0.0 0.21 10.9 0.0 2.2 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) MFS_1 PF07690.16 KKK20705.1 - 2.1e-05 23.6 0.7 2.2e-05 23.5 0.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KKK20705.1 - 0.00054 18.9 0.1 0.00062 18.7 0.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKK20706.1 - 1.7e-20 73.3 43.5 2.5e-20 72.7 43.5 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KKK20706.1 - 0.01 14.8 35.7 0.1 11.4 35.4 2.3 1 1 0 1 1 1 1 Sugar (and other) transporter Helicase_C PF00271.31 KKK20708.1 - 1e-13 51.6 0.0 1.8e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KKK20708.1 - 0.043 13.6 0.1 0.088 12.6 0.1 1.6 1 1 0 1 1 1 0 DEAD/DEAH box helicase Fungal_trans_2 PF11951.8 KKK20709.1 - 1.9e-11 43.5 0.0 7.5e-11 41.5 0.0 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain CheD PF03975.13 KKK20709.1 - 0.097 12.8 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 CheD chemotactic sensory transduction Zn_clus PF00172.18 KKK20709.1 - 0.33 11.1 2.5 0.61 10.3 2.5 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Rax2 PF12768.7 KKK20710.1 - 4.2e-73 245.4 0.5 2.4e-70 236.3 0.0 3.7 3 0 0 3 3 3 1 Cortical protein marker for cell polarity Reg_prop PF07494.11 KKK20710.1 - 0.14 12.5 0.2 8.4 7.0 0.0 4.1 3 0 0 3 3 3 0 Two component regulator propeller PRIMA1 PF16101.5 KKK20710.1 - 0.2 11.7 0.0 0.43 10.6 0.0 1.5 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 DUF5122 PF17164.4 KKK20710.1 - 0.8 10.1 17.3 7 7.0 0.0 6.4 6 0 0 6 6 6 0 Domain of unknown function (DUF5122) beta-propeller eIF3_N PF09440.10 KKK20712.1 - 7.4e-51 172.1 0.9 1.9e-50 170.7 0.9 1.8 1 0 0 1 1 1 1 eIF3 subunit 6 N terminal domain PCI PF01399.27 KKK20712.1 - 2.2e-14 53.8 0.1 7.2e-14 52.2 0.0 1.9 2 0 0 2 2 2 1 PCI domain RPN7 PF10602.9 KKK20712.1 - 0.047 13.4 0.0 0.089 12.5 0.0 1.5 1 0 0 1 1 1 0 26S proteasome subunit RPN7 Transthyretin PF00576.21 KKK20713.1 - 4.6e-33 114.2 0.0 6.1e-33 113.8 0.0 1.2 1 0 0 1 1 1 1 HIUase/Transthyretin family Big_1 PF02369.16 KKK20713.1 - 0.15 12.1 3.0 0.33 11.0 2.0 2.0 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 1) ArsA_ATPase PF02374.15 KKK20714.1 - 1.9e-114 381.9 0.0 2.2e-114 381.7 0.0 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_31 PF13614.6 KKK20714.1 - 2e-13 50.6 0.2 2.7e-12 47.0 0.0 2.4 2 1 0 2 2 2 1 AAA domain CbiA PF01656.23 KKK20714.1 - 6.8e-13 48.8 0.0 1.6e-12 47.6 0.0 1.8 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ParA PF10609.9 KKK20714.1 - 5.3e-06 26.1 1.0 0.00019 20.9 0.1 2.4 2 0 0 2 2 2 1 NUBPL iron-transfer P-loop NTPase Fer4_NifH PF00142.18 KKK20714.1 - 5.7e-06 26.0 0.1 1.3e-05 24.8 0.0 1.6 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.22 KKK20714.1 - 4.2e-05 23.3 0.2 0.0016 18.1 0.0 2.5 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain CBP_BcsQ PF06564.12 KKK20714.1 - 0.00011 21.7 0.1 0.00042 19.9 0.0 1.9 2 0 0 2 2 2 1 Cellulose biosynthesis protein BcsQ PhoH PF02562.16 KKK20714.1 - 0.027 13.9 0.0 0.078 12.4 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein A1_Propeptide PF07966.12 KKK20714.1 - 0.03 14.2 0.1 0.12 12.2 0.1 2.2 1 0 0 1 1 1 0 A1 Propeptide AAA_25 PF13481.6 KKK20714.1 - 0.044 13.4 0.0 0.18 11.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 KKK20714.1 - 0.089 13.2 0.0 0.14 12.5 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain NB-ARC PF00931.22 KKK20714.1 - 0.11 11.6 0.0 0.22 10.7 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain RecG_N PF17190.4 KKK20714.1 - 0.3 11.9 2.5 0.48 11.2 0.3 2.3 3 0 0 3 3 3 0 RecG N-terminal helical domain bZIP_1 PF00170.21 KKK20715.1 - 1e-13 51.2 4.8 2.4e-13 50.0 4.8 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KKK20715.1 - 2.5e-06 27.5 5.0 7.1e-06 26.0 5.0 1.8 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 KKK20715.1 - 0.0021 18.5 2.8 0.0021 18.5 2.8 2.0 1 1 1 2 2 2 1 bZIP Maf transcription factor DUF4711 PF15829.5 KKK20715.1 - 0.31 10.9 2.6 0.36 10.8 2.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4711) Nnf1 PF03980.14 KKK20715.1 - 0.34 11.3 7.3 0.82 10.1 7.3 1.7 1 1 0 1 1 1 0 Nnf1 ADIP PF11559.8 KKK20715.1 - 3.9 7.5 15.4 8.4 6.5 1.2 2.0 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Mis14 PF08641.12 KKK20715.1 - 3.9 7.8 10.4 0.38 11.1 0.6 2.2 1 1 1 2 2 2 0 Kinetochore protein Mis14 like Aft1_HRA PF11786.8 KKK20716.1 - 3.5e-26 91.3 7.9 3.5e-26 91.3 7.9 2.8 3 0 0 3 3 3 1 Aft1 HRA domain Aft1_HRR PF11787.8 KKK20716.1 - 2e-23 83.3 2.3 2e-23 83.3 2.3 2.3 2 0 0 2 2 2 1 Aft1 HRR domain Aft1_OSA PF11785.8 KKK20716.1 - 1.2e-20 73.6 7.6 1.2e-20 73.6 7.6 2.7 2 1 0 2 2 2 1 Aft1 osmotic stress response (OSM) domain Img2 PF05046.14 KKK20717.1 - 7.6e-27 93.4 0.0 1.4e-26 92.6 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) ARID PF01388.21 KKK20718.1 - 5.1e-20 71.9 0.0 1.4e-19 70.5 0.0 1.8 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain BAF250_C PF12031.8 KKK20718.1 - 0.0096 15.2 0.0 0.022 14.1 0.0 1.5 1 0 0 1 1 1 1 SWI/SNF-like complex subunit BAF250/Osa ICE2 PF08426.10 KKK20719.1 - 1.3e-154 515.2 13.4 1.5e-154 515.1 13.4 1.0 1 0 0 1 1 1 1 ICE2 tRNA-synt_1g PF09334.11 KKK20720.1 - 3.6e-151 503.4 0.0 4.5e-151 503.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 KKK20720.1 - 1.6e-09 36.6 0.1 2.8e-06 25.9 0.0 3.2 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) OppC_N PF12911.7 KKK20720.1 - 0.028 14.4 0.0 0.067 13.2 0.0 1.6 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C Yae1_N PF09811.9 KKK20721.1 - 2e-09 37.0 3.4 3.1e-09 36.4 3.4 1.3 1 0 0 1 1 1 1 Essential protein Yae1, N terminal FSH1 PF03959.13 KKK20745.1 - 1.4e-29 103.3 0.0 9.9e-29 100.5 0.0 2.2 1 1 0 1 1 1 1 Serine hydrolase (FSH1) NAD_kinase PF01513.21 KKK20746.1 - 2.1e-45 155.2 0.0 4.6e-41 140.9 0.0 2.1 1 1 1 2 2 2 2 ATP-NAD kinase E1-E2_ATPase PF00122.20 KKK20747.1 - 6.1e-41 139.9 8.0 9.9e-38 129.5 8.0 2.9 1 1 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 KKK20747.1 - 9.7e-30 103.6 1.1 9.7e-30 103.6 1.1 2.5 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KKK20747.1 - 1.4e-16 61.5 0.5 2.9e-13 50.6 0.0 2.6 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KKK20747.1 - 1.8e-14 53.2 0.1 6.8e-14 51.3 0.0 2.1 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 KKK20747.1 - 6.6e-14 51.8 0.0 1.3e-13 50.8 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KKK20747.1 - 1e-06 28.7 1.7 3.4e-05 23.7 0.7 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF2463 PF09591.10 KKK20747.1 - 0.012 15.6 0.5 0.037 13.9 0.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2463) HAD PF12710.7 KKK20747.1 - 0.088 13.2 0.0 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase MBOAT_2 PF13813.6 KKK20749.1 - 4.9e-20 71.6 4.6 4.9e-20 71.6 4.6 2.0 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family FERM_F1 PF18379.1 KKK20749.1 - 0.054 13.5 0.4 0.25 11.4 0.4 2.0 2 0 0 2 2 2 0 FERM F1 ubiquitin-like domain Amino_oxidase PF01593.24 KKK20750.1 - 9.1e-69 232.9 0.5 1.6e-68 232.1 0.5 1.4 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KKK20750.1 - 5.1e-08 33.0 0.1 1.3e-07 31.7 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KKK20750.1 - 0.0035 16.7 0.2 0.036 13.3 0.2 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KKK20750.1 - 0.0065 16.1 5.5 0.11 12.0 0.6 3.3 2 2 1 3 3 3 1 FAD dependent oxidoreductase Thi4 PF01946.17 KKK20750.1 - 0.0065 15.7 0.0 0.013 14.8 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 KKK20750.1 - 0.007 15.6 0.0 0.082 12.1 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KKK20750.1 - 0.018 14.3 2.1 0.14 11.4 0.2 2.9 4 0 0 4 4 4 0 FAD binding domain Pyr_redox PF00070.27 KKK20750.1 - 0.034 14.7 0.1 0.78 10.3 0.1 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KKK20750.1 - 0.039 13.9 0.7 1.8 8.5 0.1 2.9 3 0 0 3 3 3 0 FAD-NAD(P)-binding GIDA PF01134.22 KKK20750.1 - 0.17 10.9 0.0 0.34 9.9 0.0 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A HMG_CoA_synt_C PF08540.10 KKK20751.1 - 8.9e-16 58.3 0.0 9.5e-16 58.2 0.0 1.0 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal Fungal_trans PF04082.18 KKK20753.1 - 9.2e-21 74.1 0.0 1.4e-20 73.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK20753.1 - 3.7e-10 39.7 9.1 5.6e-10 39.2 9.1 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldo_ket_red PF00248.21 KKK20754.1 - 5.1e-38 130.9 0.0 4.5e-37 127.8 0.0 1.9 1 1 0 1 1 1 1 Aldo/keto reductase family RTA1 PF04479.13 KKK20755.1 - 8.6e-58 195.4 10.3 8.6e-58 195.4 10.3 1.7 1 1 1 2 2 2 1 RTA1 like protein ADH_zinc_N PF00107.26 KKK20755.1 - 1.1e-20 73.9 0.1 2.3e-20 72.9 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KKK20755.1 - 1e-18 68.7 0.0 1.7e-18 68.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KKK20755.1 - 1.8e-09 37.5 0.0 7.7e-09 35.4 0.0 1.9 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain DUF3671 PF12420.8 KKK20755.1 - 1.3 9.1 5.8 6.7 6.8 0.4 3.3 2 1 1 3 3 3 0 Protein of unknown function Hydrolase_6 PF13344.6 KKK20756.1 - 7.7e-24 83.7 0.0 1.5e-23 82.8 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KKK20756.1 - 9.8e-19 67.2 0.0 2.1e-18 66.2 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 KKK20756.1 - 0.0073 16.6 0.0 2 8.6 0.0 3.2 2 1 1 3 3 3 1 haloacid dehalogenase-like hydrolase Apt1 PF10351.9 KKK20756.1 - 0.16 10.8 0.0 0.34 9.7 0.0 1.4 2 0 0 2 2 2 0 Golgi-body localisation protein domain Aldo_ket_red PF00248.21 KKK20757.1 - 1.7e-51 175.2 0.0 4.9e-51 173.7 0.0 1.6 1 1 0 1 1 1 1 Aldo/keto reductase family RRM_1 PF00076.22 KKK20759.1 - 5.1e-18 64.7 0.0 6.8e-18 64.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KKK20759.1 - 0.022 14.8 0.0 0.03 14.3 0.0 1.2 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 KKK20759.1 - 0.036 13.7 0.0 0.056 13.0 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ATP-synt_Eps PF04627.13 KKK20760.1 - 1.6e-23 82.4 1.0 2.2e-23 82.0 1.0 1.2 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain DUF676 PF05057.14 KKK20761.1 - 6.5e-06 25.8 0.0 5e-05 22.9 0.0 2.1 2 0 0 2 2 2 1 Putative serine esterase (DUF676) Hydrolase_4 PF12146.8 KKK20761.1 - 0.00064 19.1 0.0 0.0011 18.3 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KKK20761.1 - 0.014 16.0 0.2 0.051 14.2 0.0 2.0 2 0 0 2 2 2 0 Alpha/beta hydrolase family PGAP1 PF07819.13 KKK20761.1 - 0.083 12.6 0.0 0.33 10.6 0.0 2.1 1 1 0 1 1 1 0 PGAP1-like protein Abhydrolase_8 PF06259.12 KKK20761.1 - 0.094 12.3 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase Mak10 PF04112.13 KKK20763.1 - 1e-65 220.3 0.1 1.9e-65 219.4 0.1 1.4 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase Cpn60_TCP1 PF00118.24 KKK20764.1 - 1.5e-86 291.0 9.2 3.2e-86 289.9 9.2 1.5 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family SnoaL_4 PF13577.6 KKK20764.1 - 0.27 11.4 0.6 2 8.5 0.2 2.5 2 1 1 3 3 3 0 SnoaL-like domain Chlorosome_CsmC PF11098.8 KKK20764.1 - 0.6 10.1 8.3 6.2 6.8 0.1 3.8 4 0 0 4 4 4 0 Chlorosome envelope protein C TPMT PF05724.11 KKK20766.1 - 5.9e-23 81.7 0.0 2.7e-22 79.5 0.0 1.8 2 0 0 2 2 2 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_23 PF13489.6 KKK20766.1 - 1.8e-07 31.1 0.0 2.6e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKK20766.1 - 3.3e-05 24.5 0.0 0.00037 21.1 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KKK20766.1 - 4.6e-05 24.0 0.0 0.00016 22.3 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KKK20766.1 - 0.00014 21.7 0.0 0.57 10.0 0.1 2.1 2 0 0 2 2 2 2 Methyltransferase domain VbhA PF18495.1 KKK20766.1 - 0.0087 15.9 0.1 0.018 14.9 0.1 1.5 1 0 0 1 1 1 1 Antitoxin VbhA Methyltransf_12 PF08242.12 KKK20766.1 - 0.034 14.9 0.0 0.11 13.3 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Zn_clus PF00172.18 KKK20767.1 - 7.1e-10 38.9 8.9 1.3e-09 38.0 8.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KKK20767.1 - 8.1e-08 31.6 0.0 1.7e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short PF00106.25 KKK20768.1 - 1.5e-34 119.1 0.0 7.1e-34 117.0 0.0 1.8 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KKK20768.1 - 2.3e-30 105.9 0.0 1e-29 103.8 0.0 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KKK20768.1 - 4.3e-11 43.1 0.1 1.2e-09 38.4 0.0 2.6 2 1 0 2 2 2 1 KR domain NAD_binding_7 PF13241.6 KKK20768.1 - 0.036 14.5 0.0 0.13 12.7 0.0 1.9 2 1 0 2 2 2 0 Putative NAD(P)-binding 3Beta_HSD PF01073.19 KKK20768.1 - 0.045 12.8 0.0 0.068 12.2 0.0 1.4 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KKK20768.1 - 0.11 11.9 0.0 0.3 10.5 0.0 1.7 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Mito_carr PF00153.27 KKK20770.1 - 1.3e-63 210.9 0.9 9.7e-20 70.3 0.0 4.2 3 1 1 4 4 4 4 Mitochondrial carrier protein Serine_protease PF18405.1 KKK20770.1 - 0.19 10.8 2.6 0.26 10.4 0.0 2.3 3 0 0 3 3 3 0 Gammaproteobacterial serine protease F-box-like PF12937.7 KKK20771.1 - 3.6e-08 33.2 0.1 7.3e-08 32.2 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KKK20771.1 - 4.3e-06 26.5 0.1 1.1e-05 25.1 0.1 1.7 1 0 0 1 1 1 1 F-box domain MIT PF04212.18 KKK20771.1 - 0.043 13.9 0.7 0.09 12.9 0.7 1.5 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain TPR_2 PF07719.17 KKK20771.1 - 0.12 12.5 0.7 1.4 9.2 0.9 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat EXS PF03124.14 KKK20772.1 - 6e-102 341.3 12.0 6.9e-102 341.2 12.0 1.0 1 0 0 1 1 1 1 EXS family RhoGAP PF00620.27 KKK20773.1 - 8e-16 58.2 0.1 1.7e-15 57.2 0.1 1.4 1 0 0 1 1 1 1 RhoGAP domain DEP PF00610.21 KKK20773.1 - 4e-11 42.8 0.0 7.9e-11 41.9 0.0 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) FCH PF00611.23 KKK20773.1 - 2.2e-07 31.1 0.0 7.8e-07 29.3 0.0 2.0 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain DUF5343 PF17278.2 KKK20773.1 - 0.14 12.2 0.1 0.29 11.2 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5343) AA_permease PF00324.21 KKK20774.1 - 8.1e-122 407.2 38.9 5.6e-121 404.5 33.6 2.0 1 1 1 2 2 2 2 Amino acid permease AA_permease_2 PF13520.6 KKK20774.1 - 8.6e-28 97.3 34.5 1.2e-27 96.8 34.5 1.1 1 0 0 1 1 1 1 Amino acid permease DUF4781 PF16013.5 KKK20774.1 - 0.012 14.4 0.2 0.024 13.5 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4781) LSM PF01423.22 KKK20775.1 - 8.5e-15 54.2 0.1 9.8e-15 54.0 0.1 1.1 1 0 0 1 1 1 1 LSM domain DNA_pol_A_exo1 PF01612.20 KKK20776.1 - 2e-21 76.5 0.0 2.9e-21 76.0 0.0 1.1 1 0 0 1 1 1 1 3'-5' exonuclease Ribosomal_L26 PF16906.5 KKK20777.1 - 1.3e-35 121.6 2.3 1.7e-35 121.4 2.3 1.1 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 KKK20777.1 - 1.1e-05 25.2 0.6 2.7e-05 24.0 0.6 1.6 1 0 0 1 1 1 1 KOW motif DUF1223 PF06764.11 KKK20777.1 - 0.043 13.8 0.0 0.058 13.4 0.0 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1223) AAA_14 PF13173.6 KKK20778.1 - 0.0036 17.3 0.0 0.007 16.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KKK20778.1 - 0.024 15.0 0.0 0.058 13.8 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.6 KKK20778.1 - 0.14 12.8 0.0 0.25 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.10 KKK20778.1 - 0.19 11.1 0.0 0.3 10.5 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 ATPase PF06745.13 KKK20778.1 - 0.21 10.9 0.0 0.32 10.3 0.0 1.2 1 0 0 1 1 1 0 KaiC Pex2_Pex12 PF04757.14 KKK20779.1 - 1.7e-46 158.6 8.1 2.3e-46 158.2 8.1 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.6 KKK20779.1 - 1.2e-11 44.2 9.2 2e-11 43.5 9.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KKK20779.1 - 3.4e-11 42.8 5.9 4.9e-11 42.3 5.9 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KKK20779.1 - 6.8e-11 42.3 10.2 1.1e-10 41.7 10.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KKK20779.1 - 1.7e-10 40.5 7.2 2.8e-10 39.9 7.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KKK20779.1 - 2.9e-09 36.8 3.6 2.9e-09 36.8 3.6 1.6 1 1 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 KKK20779.1 - 3e-08 33.4 6.6 5e-08 32.7 6.6 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KKK20779.1 - 1.9e-07 30.9 7.0 3.3e-07 30.2 7.0 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 KKK20779.1 - 3.4e-06 27.2 7.1 7.2e-06 26.2 7.1 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 KKK20779.1 - 8.3e-06 25.9 8.4 1.5e-05 25.0 8.4 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_10 PF16685.5 KKK20779.1 - 0.0042 17.2 6.3 0.0075 16.4 6.3 1.4 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-ANAPC11 PF12861.7 KKK20779.1 - 0.065 13.3 3.7 0.14 12.2 3.8 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 KKK20779.1 - 0.069 12.9 6.5 0.14 12.0 6.5 1.5 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.6 KKK20779.1 - 0.092 12.6 3.0 0.16 11.8 3.0 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein FYVE PF01363.21 KKK20779.1 - 1.7 8.9 6.9 6.4 7.0 7.0 1.9 1 1 0 1 1 1 0 FYVE zinc finger zf-RING_11 PF17123.5 KKK20779.1 - 3.1 7.6 7.8 0.79 9.5 4.1 2.0 2 0 0 2 2 2 0 RING-like zinc finger Rtf2 PF04641.12 KKK20779.1 - 6.8 6.0 6.5 0.5 9.7 1.6 1.7 2 0 0 2 2 2 0 Rtf2 RING-finger IBR PF01485.21 KKK20779.1 - 9.1 6.6 8.8 27 5.1 8.8 1.8 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain VHS PF00790.19 KKK20797.1 - 1.7e-43 147.9 0.0 6.7e-43 145.9 0.0 1.9 2 0 0 2 2 2 1 VHS domain Alpha_adaptinC2 PF02883.20 KKK20797.1 - 3.3e-22 78.9 0.1 3.3e-22 78.9 0.1 1.6 2 0 0 2 2 2 1 Adaptin C-terminal domain GAT PF03127.14 KKK20797.1 - 3.6e-21 75.2 0.3 1.2e-20 73.6 0.0 2.1 2 0 0 2 2 2 1 GAT domain GGA_N-GAT PF18308.1 KKK20797.1 - 2.1e-10 40.0 0.5 4.4e-07 29.4 0.1 3.1 2 0 0 2 2 2 2 GGA N-GAT domain Aldo_ket_red PF00248.21 KKK20799.1 - 4.6e-42 144.2 0.0 7.8e-38 130.3 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family zf-H2C2_2 PF13465.6 KKK20800.1 - 2.8e-07 30.7 7.4 2.5e-06 27.7 0.6 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_6 PF13912.6 KKK20800.1 - 7e-07 29.1 1.5 0.011 15.7 0.0 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KKK20800.1 - 7.6e-06 26.1 0.3 7.6e-06 26.1 0.3 3.8 3 1 0 3 3 3 1 Zinc finger, C2H2 type FOXP-CC PF16159.5 KKK20800.1 - 3.1e-05 24.5 5.2 0.19 12.4 0.0 3.1 2 1 1 3 3 3 2 FOXP coiled-coil domain zf-C2H2_4 PF13894.6 KKK20800.1 - 0.00017 22.2 7.4 0.0052 17.5 0.2 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KKK20800.1 - 0.13 12.6 0.9 2.7 8.4 0.2 3.0 3 1 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 KKK20800.1 - 0.19 11.5 0.5 0.56 10.0 0.0 2.0 2 0 0 2 2 2 0 zinc-finger C2H2-type zf_ZIC PF18366.1 KKK20800.1 - 7.4 6.8 8.5 3 8.0 1.7 3.3 3 1 0 3 3 3 0 Zic proteins zinc finger domain UCR_hinge PF02320.16 KKK20801.1 - 1.4e-24 86.1 8.2 1.7e-24 85.8 8.2 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein UPF0203 PF05254.12 KKK20801.1 - 0.33 11.2 5.5 0.59 10.4 5.5 1.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0203) PIP5K PF01504.18 KKK20803.1 - 8.9e-35 120.2 0.1 8.9e-27 94.0 0.3 2.6 1 1 1 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.24 KKK20803.1 - 4.2e-28 98.2 0.0 6.7e-28 97.6 0.0 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.21 KKK20803.1 - 1.5e-14 53.9 3.7 1.5e-14 53.9 3.7 1.9 2 0 0 2 2 2 1 FYVE zinc finger XPC-binding PF09280.11 KKK20803.1 - 0.078 12.7 0.7 0.2 11.4 0.7 1.7 1 0 0 1 1 1 0 XPC-binding domain DUF3391 PF11871.8 KKK20803.1 - 0.53 10.8 5.6 0.2 12.2 0.2 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3391) C1_1 PF00130.22 KKK20803.1 - 1.1 9.3 10.5 0.023 14.6 3.3 2.0 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) TPP1 PF10341.9 KKK20804.1 - 0.0088 16.0 0.0 0.023 14.7 0.0 1.8 1 0 0 1 1 1 1 Shelterin complex subunit, TPP1/ACD TRAM_LAG1_CLN8 PF03798.16 KKK20805.1 - 4.5e-54 183.2 19.0 4.5e-54 183.2 19.0 1.6 2 0 0 2 2 2 1 TLC domain SUIM_assoc PF16619.5 KKK20805.1 - 0.14 12.2 0.1 0.27 11.3 0.1 1.4 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Scaffolding_pro PF11418.8 KKK20806.1 - 0.37 11.4 7.5 0.069 13.7 0.3 3.6 3 0 0 3 3 3 0 Phi29 scaffolding protein Ribosomal_L27e PF01777.18 KKK20807.1 - 9e-39 131.7 2.9 1.4e-38 131.1 2.9 1.3 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.29 KKK20807.1 - 0.00022 21.0 0.7 0.00063 19.6 0.2 2.1 2 0 0 2 2 2 1 KOW motif RCC1 PF00415.18 KKK20808.1 - 7.6e-61 202.5 7.8 3.7e-11 43.5 0.1 7.4 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KKK20808.1 - 1.1e-34 117.5 38.3 5.5e-09 35.6 1.2 6.7 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat TFIIA PF03153.13 KKK20808.1 - 0.12 12.4 4.9 0.18 11.8 4.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Transp_cyt_pur PF02133.15 KKK20809.1 - 3e-49 168.0 39.9 3.4e-49 167.8 39.9 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin eIF3g PF12353.8 KKK20810.1 - 9.2e-45 152.1 2.8 1.4e-44 151.5 2.8 1.3 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.22 KKK20810.1 - 4e-17 61.8 0.0 6.8e-17 61.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH_7 PF18586.1 KKK20810.1 - 0.021 15.1 0.2 0.058 13.7 0.2 1.7 1 0 0 1 1 1 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 1 ribosomal_L24 PF17136.4 KKK20810.1 - 0.088 13.2 0.9 0.088 13.2 0.9 2.1 2 0 0 2 2 2 0 Ribosomal proteins 50S L24/mitochondrial 39S L24 NDT80_PhoG PF05224.12 KKK20811.1 - 9.3e-26 91.2 0.1 1.3e-25 90.7 0.1 1.2 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family Beta-lactamase PF00144.24 KKK20812.1 - 2.3e-44 152.0 0.0 5.1e-44 150.9 0.0 1.4 1 1 0 1 1 1 1 Beta-lactamase Beta-lactamase2 PF13354.6 KKK20812.1 - 0.1 12.2 0.2 0.29 10.7 0.0 1.8 2 1 0 2 2 2 0 Beta-lactamase enzyme family Methyltransf_23 PF13489.6 KKK20814.1 - 6.8e-13 48.8 0.0 9e-13 48.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKK20814.1 - 3.2e-09 37.4 0.0 5.4e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KKK20814.1 - 1.3e-08 35.4 0.0 2e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KKK20814.1 - 5.7e-08 32.7 0.0 6.9e-08 32.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KKK20814.1 - 2.9e-06 26.8 0.0 3.7e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 KKK20814.1 - 7.8e-06 26.6 0.0 1.2e-05 25.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 KKK20814.1 - 8.5e-06 24.9 0.0 1.2e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) DUF938 PF06080.12 KKK20814.1 - 0.0041 16.9 0.0 0.052 13.3 0.0 2.6 1 1 0 1 1 1 1 Protein of unknown function (DUF938) Methyltransf_24 PF13578.6 KKK20814.1 - 0.011 16.7 0.0 0.024 15.7 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain NMO PF03060.15 KKK20815.1 - 4.3e-46 157.8 4.8 6.8e-46 157.2 3.4 1.9 1 1 1 2 2 2 1 Nitronate monooxygenase IMPDH PF00478.25 KKK20815.1 - 1.4e-10 40.7 0.9 5.1e-10 38.9 0.9 1.9 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 KKK20815.1 - 1.1e-05 24.7 1.7 1.7e-05 24.0 1.7 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 KKK20815.1 - 0.01 15.0 1.1 0.022 13.9 1.1 1.5 1 0 0 1 1 1 0 Conserved region in glutamate synthase DHO_dh PF01180.21 KKK20815.1 - 0.071 12.3 0.2 0.13 11.5 0.2 1.3 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase Pterin_bind PF00809.22 KKK20816.1 - 1e-63 215.3 0.1 6.6e-61 206.1 0.1 2.1 1 1 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.20 KKK20816.1 - 8.8e-32 109.9 0.0 2.4e-31 108.5 0.0 1.7 2 0 0 2 2 2 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) AflR PF08493.10 KKK20816.1 - 0.09 12.2 1.5 0.17 11.3 1.5 1.4 1 0 0 1 1 1 0 Aflatoxin regulatory protein CT_A_B PF02626.15 KKK20817.1 - 1.4e-75 254.3 0.0 2e-75 253.9 0.0 1.2 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain A and B CPSase_L_D2 PF02786.17 KKK20817.1 - 6.6e-54 182.6 0.0 1.1e-53 181.8 0.0 1.2 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.19 KKK20817.1 - 7.4e-34 116.1 0.0 1.3e-33 115.4 0.0 1.4 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_carb_N PF00289.22 KKK20817.1 - 8.7e-29 100.3 0.0 4.5e-28 98.0 0.0 2.0 2 0 0 2 2 2 1 Biotin carboxylase, N-terminal domain CT_C_D PF02682.16 KKK20817.1 - 2.3e-14 53.6 0.0 3.9e-14 52.9 0.0 1.4 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain C and D Dala_Dala_lig_C PF07478.13 KKK20817.1 - 8.6e-07 28.7 0.0 1.6e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_5 PF13549.6 KKK20817.1 - 0.019 14.4 0.0 0.037 13.5 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain ATP-grasp PF02222.22 KKK20817.1 - 0.047 13.3 0.0 0.074 12.6 0.0 1.3 1 0 0 1 1 1 0 ATP-grasp domain Homeobox_KN PF05920.11 KKK20818.1 - 9.1e-17 60.7 1.2 9.1e-17 60.7 1.2 2.0 2 0 0 2 2 2 1 Homeobox KN domain Homeodomain PF00046.29 KKK20818.1 - 0.00015 21.6 0.5 0.00034 20.4 0.5 1.7 1 0 0 1 1 1 1 Homeodomain HTH_Tnp_Tc5 PF03221.16 KKK20818.1 - 0.0021 18.0 0.0 0.0052 16.8 0.0 1.7 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain zf-C2H2_4 PF13894.6 KKK20818.1 - 0.0048 17.6 1.3 0.0048 17.6 1.3 4.9 5 0 0 5 5 5 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KKK20818.1 - 0.019 15.4 17.3 2.4 8.8 1.3 4.3 4 0 0 4 4 4 0 Zinc finger, C2H2 type 2OG-FeII_Oxy_2 PF13532.6 KKK20819.1 - 1.3e-36 126.6 0.0 1.9e-36 126.1 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily zf-GRF PF06839.12 KKK20819.1 - 6e-05 23.1 5.9 0.0001 22.3 5.9 1.4 1 0 0 1 1 1 1 GRF zinc finger UQ_con PF00179.26 KKK20820.1 - 2.2e-10 40.3 0.2 4e-10 39.5 0.2 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KKK20820.1 - 0.051 13.9 0.1 0.1 12.9 0.1 1.4 1 0 0 1 1 1 0 RWD domain LicD PF04991.13 KKK20822.1 - 1.7e-21 77.5 7.7 3.5e-16 60.0 1.7 2.3 1 1 1 2 2 2 2 LicD family Fungal_trans PF04082.18 KKK20823.1 - 0.00019 20.6 0.0 0.00035 19.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK20823.1 - 0.00069 19.7 11.7 0.0012 18.9 11.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3287 PF11690.8 KKK20823.1 - 0.16 11.7 0.6 0.53 10.0 0.6 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3287) ATF7IP_BD PF16788.5 KKK20823.1 - 1.1 9.3 4.4 2 8.5 4.4 1.3 1 0 0 1 1 1 0 ATF-interacting protein binding domain Clathrin PF00637.20 KKK20824.1 - 9.9e-24 83.8 4.7 6.9e-21 74.6 2.9 2.6 2 0 0 2 2 2 2 Region in Clathrin and VPS VPS11_C PF12451.8 KKK20824.1 - 4e-19 68.6 0.9 9.5e-19 67.4 0.9 1.7 1 0 0 1 1 1 1 Vacuolar protein sorting protein 11 C terminal zf-C3H2C3 PF17122.5 KKK20824.1 - 2.9e-07 30.4 4.2 5.7e-07 29.5 4.2 1.5 1 0 0 1 1 1 1 Zinc-finger zf-C3HC4_2 PF13923.6 KKK20824.1 - 5e-06 26.3 3.6 1e-05 25.2 3.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) TPR_14 PF13428.6 KKK20824.1 - 0.00023 21.7 0.2 0.074 13.9 0.0 3.6 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 KKK20824.1 - 0.00053 19.6 0.1 0.0022 17.6 0.1 2.1 1 0 0 1 1 1 1 TPR repeat zf-RING_2 PF13639.6 KKK20824.1 - 0.0018 18.5 6.0 0.0037 17.6 6.0 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 KKK20824.1 - 0.0095 16.2 4.2 0.019 15.2 4.2 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain DUF4810 PF16068.5 KKK20824.1 - 0.012 16.2 0.7 3.9 8.1 0.0 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4810) zf-C3HC4 PF00097.25 KKK20824.1 - 0.016 15.1 2.6 0.033 14.1 2.6 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KKK20824.1 - 0.016 15.1 5.1 0.034 14.1 5.1 1.5 1 0 0 1 1 1 0 zinc-RING finger domain TPR_16 PF13432.6 KKK20824.1 - 0.041 14.5 0.7 0.13 12.9 0.1 2.2 3 0 0 3 3 1 0 Tetratricopeptide repeat CdiI_2 PF18593.1 KKK20824.1 - 0.14 12.8 0.9 26 5.6 0.0 3.6 3 0 0 3 3 3 0 CdiI immunity protein zf-RING-like PF08746.11 KKK20824.1 - 0.31 11.4 2.8 0.68 10.3 2.8 1.5 1 0 0 1 1 1 0 RING-like domain zf-ANAPC11 PF12861.7 KKK20824.1 - 0.37 10.9 1.4 0.82 9.8 1.4 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 KKK20824.1 - 0.62 10.1 3.4 1.6 8.8 3.4 1.6 1 0 0 1 1 1 0 RING-type zinc-finger Vps39_1 PF10366.9 KKK20824.1 - 0.79 10.0 3.7 3.2 8.1 1.6 2.9 2 1 1 3 3 3 0 Vacuolar sorting protein 39 domain 1 ANAPC3 PF12895.7 KKK20824.1 - 1.4 9.2 6.8 4.1 7.7 0.4 3.2 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 KKK20824.1 - 1.7 8.6 4.2 3.1 7.8 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat eIF3_N PF09440.10 KKK20824.1 - 4.4 7.7 6.4 1.1 9.7 1.9 2.4 2 1 1 3 3 2 0 eIF3 subunit 6 N terminal domain TPR_2 PF07719.17 KKK20824.1 - 8.2 6.8 10.2 0.22 11.8 0.3 3.3 4 0 0 4 4 2 0 Tetratricopeptide repeat Apc13p PF05839.11 KKK20825.1 - 0.059 13.6 0.2 6 7.1 0.2 3.1 2 0 0 2 2 2 0 Apc13p protein DTHCT PF08070.11 KKK20825.1 - 0.16 12.7 0.1 0.16 12.7 0.1 3.8 4 0 0 4 4 4 0 DTHCT (NUC029) region Polysacc_deac_1 PF01522.21 KKK20826.1 - 1e-27 96.5 0.0 2.6e-27 95.2 0.0 1.7 1 1 0 1 1 1 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.19 KKK20826.1 - 1.5e-08 35.0 44.0 2.2e-05 24.8 15.4 2.9 2 1 0 2 2 2 2 Chitin recognition protein HEAT_2 PF13646.6 KKK20827.1 - 8.9e-05 22.8 0.0 0.0041 17.5 0.0 3.3 3 2 0 3 3 3 1 HEAT repeats MMS19_C PF12460.8 KKK20827.1 - 0.00025 20.3 0.1 0.043 12.9 0.0 2.6 1 1 2 3 3 3 2 RNAPII transcription regulator C-terminal RTP1_C1 PF10363.9 KKK20827.1 - 0.00055 20.1 0.0 0.0012 19.0 0.0 1.5 1 0 0 1 1 1 1 Required for nuclear transport of RNA pol II C-terminus 1 HEAT PF02985.22 KKK20827.1 - 0.0007 19.6 1.7 2.2 8.7 0.0 4.5 5 0 0 5 5 5 1 HEAT repeat HEAT_EZ PF13513.6 KKK20827.1 - 0.0033 17.9 4.0 11 6.6 0.0 5.1 6 0 0 6 6 6 1 HEAT-like repeat Adaptin_N PF01602.20 KKK20827.1 - 0.021 13.4 0.1 12 4.3 0.0 2.9 2 1 1 3 3 3 0 Adaptin N terminal region Vac14_Fab1_bd PF12755.7 KKK20827.1 - 0.027 15.1 0.0 0.32 11.6 0.0 2.4 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region V-ATPase_H_C PF11698.8 KKK20827.1 - 0.049 13.8 0.0 1.9 8.6 0.0 2.4 2 0 0 2 2 2 0 V-ATPase subunit H DRIM PF07539.12 KKK20827.1 - 0.055 11.8 1.6 2.1 6.5 1.0 2.4 1 1 1 2 2 2 0 Down-regulated in metastasis Cnd1 PF12717.7 KKK20827.1 - 0.061 13.4 0.1 0.19 11.8 0.0 1.8 2 1 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 TRAM_LAG1_CLN8 PF03798.16 KKK20828.1 - 3.5e-39 134.6 19.7 3.5e-39 134.6 19.7 1.6 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.11 KKK20828.1 - 4.2e-22 77.6 1.4 6.5e-22 77.0 0.0 2.1 2 0 0 2 2 2 1 TRAM1-like protein Thioredoxin_4 PF13462.6 KKK20828.1 - 0.077 13.2 0.1 0.12 12.5 0.1 1.3 1 0 0 1 1 1 0 Thioredoxin OPT PF03169.15 KKK20829.1 - 6.5e-164 547.0 53.6 7.4e-164 546.8 53.6 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DAO PF01266.24 KKK20830.1 - 1e-28 101.0 0.0 1.2e-28 100.7 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase ApbA PF02558.16 KKK20830.1 - 0.06 13.0 1.1 0.11 12.2 1.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DUF604 PF04646.12 KKK20830.1 - 0.15 11.4 0.4 0.24 10.8 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF604 Pyr_redox_2 PF07992.14 KKK20830.1 - 0.17 11.1 0.1 0.26 10.5 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Transglut_core PF01841.19 KKK20832.1 - 4e-12 46.6 0.0 7e-12 45.8 0.0 1.3 1 0 0 1 1 1 1 Transglutaminase-like superfamily Gln_amidase PF15644.6 KKK20832.1 - 0.016 16.2 0.0 0.041 14.9 0.0 1.8 1 0 0 1 1 1 0 Papain fold toxin 1, glutamine deamidase Sugar_tr PF00083.24 KKK20833.1 - 1.5e-116 389.9 19.5 1.8e-116 389.7 19.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKK20833.1 - 2e-26 92.8 41.7 2e-25 89.5 16.4 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KKK20833.1 - 0.0058 15.1 1.1 0.0058 15.1 1.1 1.9 3 0 0 3 3 3 1 Fungal trichothecene efflux pump (TRI12) DUF2530 PF10745.9 KKK20833.1 - 0.13 12.5 1.7 0.84 9.9 1.7 2.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2530) Phage_holin_2_3 PF16080.5 KKK20833.1 - 0.16 11.7 0.1 0.16 11.7 0.1 2.9 3 0 0 3 3 3 0 Bacteriophage holin family HP1 DUF4470 PF14737.6 KKK20834.1 - 3.7e-27 94.4 0.1 7.8e-27 93.3 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) KTI12 PF08433.10 KKK20839.1 - 3.5e-64 216.9 0.0 1.2e-63 215.1 0.0 1.8 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.6 KKK20839.1 - 0.00081 19.6 0.1 0.003 17.7 0.0 2.0 3 0 0 3 3 3 1 AAA domain Methyltransf_16 PF10294.9 KKK20840.1 - 1.4e-13 50.9 0.0 2e-13 50.4 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase zf-C2H2 PF00096.26 KKK20841.1 - 0.019 15.4 1.7 0.62 10.6 0.1 3.2 2 0 0 2 2 2 0 Zinc finger, C2H2 type Histone PF00125.24 KKK20856.1 - 5.3e-42 143.3 0.0 6.4e-42 143.0 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 KKK20856.1 - 0.00048 20.2 0.0 0.00079 19.5 0.0 1.3 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 KKK20856.1 - 0.002 18.5 0.1 0.0027 18.0 0.1 1.2 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 KKK20856.1 - 0.055 13.8 0.4 0.11 12.8 0.4 1.4 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 KKK20856.1 - 0.11 12.6 0.0 0.15 12.2 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit DER1 PF04511.15 KKK20857.1 - 7.7e-52 176.0 5.5 8.9e-52 175.8 5.5 1.0 1 0 0 1 1 1 1 Der1-like family Transp_cyt_pur PF02133.15 KKK20858.1 - 1.3e-29 103.3 32.6 7.3e-29 100.8 31.9 2.1 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Cation_efflux PF01545.21 KKK20858.1 - 7.1e-05 22.6 3.6 0.0003 20.6 3.6 2.1 1 1 0 1 1 1 1 Cation efflux family Methyltransf_2 PF00891.18 KKK20859.1 - 2.8e-12 46.4 0.0 2.3e-11 43.4 0.0 2.1 1 1 1 2 2 2 1 O-methyltransferase domain Methyltransf_23 PF13489.6 KKK20859.1 - 0.0011 18.8 0.0 0.0023 17.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain TPR_8 PF13181.6 KKK20859.1 - 0.33 11.3 1.6 10 6.6 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat ketoacyl-synt PF00109.26 KKK20861.1 - 2.2e-31 109.4 0.0 2.5e-31 109.2 0.0 1.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain MFS_1 PF07690.16 KKK20862.1 - 3.9e-16 58.9 41.2 3.9e-16 58.9 41.2 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Adaptin_N PF01602.20 KKK20864.1 - 1.6e-113 380.0 0.1 2.1e-113 379.6 0.1 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.10 KKK20864.1 - 5.5e-59 198.6 4.6 1.3e-58 197.4 4.6 1.7 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain Coatomer_g_Cpla PF16381.5 KKK20864.1 - 2.5e-34 117.9 0.5 2e-33 114.9 0.1 2.7 2 0 0 2 2 2 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT_2 PF13646.6 KKK20864.1 - 4.9e-18 65.3 0.8 3.7e-11 43.2 0.0 5.6 5 1 1 6 6 6 3 HEAT repeats Cnd1 PF12717.7 KKK20864.1 - 5.8e-09 36.2 8.0 0.0018 18.4 0.2 5.0 4 1 2 6 6 6 2 non-SMC mitotic condensation complex subunit 1 HEAT_PBS PF03130.16 KKK20864.1 - 0.0055 17.3 1.9 14 6.7 0.0 5.0 5 0 0 5 5 5 1 PBS lyase HEAT-like repeat UNC45-central PF11701.8 KKK20864.1 - 0.1 12.6 1.8 31 4.5 0.1 3.9 3 1 0 3 3 3 0 Myosin-binding striated muscle assembly central DUF5010 PF16402.5 KKK20864.1 - 0.13 11.1 0.0 2.3 6.9 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5010) HEAT PF02985.22 KKK20864.1 - 0.31 11.4 7.5 61 4.3 0.2 5.8 6 0 0 6 6 6 0 HEAT repeat TFIID-18kDa PF02269.16 KKK20865.1 - 6.7e-23 80.5 0.0 1.5e-22 79.4 0.0 1.6 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit CENP-T_C PF15511.6 KKK20865.1 - 0.055 13.6 0.1 0.1 12.7 0.1 1.4 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 KKK20865.1 - 0.065 13.4 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) Histone PF00125.24 KKK20865.1 - 0.085 13.2 0.0 0.085 13.2 0.0 2.8 3 0 0 3 3 3 0 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 KKK20865.1 - 0.093 13.1 0.0 0.18 12.2 0.0 1.4 1 0 0 1 1 1 0 CENP-S protein Bromo_TP PF07524.13 KKK20865.1 - 0.1 12.6 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated PPR_2 PF13041.6 KKK20866.1 - 1.3e-11 44.5 5.2 0.00032 20.8 0.0 4.6 4 1 1 5 5 5 3 PPR repeat family PPR_3 PF13812.6 KKK20866.1 - 9.6e-09 35.2 0.8 0.027 14.5 0.0 3.8 3 0 0 3 3 3 3 Pentatricopeptide repeat domain DUF5617 PF18493.1 KKK20866.1 - 0.0025 17.9 0.6 0.017 15.2 0.7 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF5617) PPR PF01535.20 KKK20866.1 - 0.0038 17.4 0.3 1.2 9.6 0.0 3.9 4 0 0 4 4 4 1 PPR repeat zf-CCHC_3 PF13917.6 KKK20867.1 - 0.051 13.5 0.5 0.051 13.5 0.5 2.1 2 0 0 2 2 2 0 Zinc knuckle cwf18 PF08315.12 KKK20868.1 - 5.5e-45 153.3 5.8 1e-44 152.5 5.8 1.4 1 0 0 1 1 1 1 cwf18 pre-mRNA splicing factor KicB PF03882.14 KKK20868.1 - 0.061 13.5 0.1 0.11 12.7 0.1 1.5 1 0 0 1 1 1 0 MukF winged-helix domain Cys_rich_VLP PF14194.6 KKK20870.1 - 0.017 15.3 1.5 0.026 14.6 1.5 1.4 1 0 0 1 1 1 0 Cysteine-rich VLP AMPK1_CBM PF16561.5 KKK20871.1 - 0.00011 22.4 0.0 0.00019 21.5 0.0 1.4 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase Tom6 PF17112.5 KKK20872.1 - 4.2e-05 23.0 0.0 5.1e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom6, fungal Fungal_trans PF04082.18 KKK20873.1 - 5e-23 81.5 4.4 8.3e-23 80.8 4.4 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain RNA_pol_Rpb2_6 PF00562.28 KKK20874.1 - 3.3e-123 411.6 0.0 4.6e-123 411.1 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 KKK20874.1 - 5.3e-61 205.7 0.0 9.6e-61 204.8 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 KKK20874.1 - 3e-46 157.5 0.0 5.6e-46 156.6 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 KKK20874.1 - 5.6e-33 113.2 0.1 1.5e-32 111.8 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.16 KKK20874.1 - 1e-25 89.7 0.5 2.6e-25 88.4 0.1 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.13 KKK20874.1 - 5.6e-24 84.2 0.7 1.5e-23 82.8 0.7 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.17 KKK20874.1 - 5e-22 78.2 0.4 1.7e-21 76.5 0.4 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 CTNNBL PF08216.11 KKK20875.1 - 1.9e-39 134.0 1.1 5.6e-39 132.5 0.1 2.4 3 0 0 3 3 3 1 Catenin-beta-like, Arm-motif containing nuclear Arm PF00514.23 KKK20875.1 - 0.00079 19.4 0.7 2.2 8.4 0.0 3.2 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat Mo25 PF08569.11 KKK20875.1 - 0.006 16.0 2.3 0.019 14.3 2.2 1.9 1 1 0 1 1 1 1 Mo25-like Arm_3 PF16186.5 KKK20875.1 - 0.051 13.2 0.6 0.22 11.1 0.6 2.1 1 0 0 1 1 1 0 Atypical Arm repeat RNA_pol_Rpc34 PF05158.12 KKK20876.1 - 1.1e-119 399.8 0.0 1.2e-119 399.6 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit HTH_46 PF15977.5 KKK20876.1 - 0.034 14.2 0.1 0.074 13.1 0.1 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA binding MarR PF01047.22 KKK20876.1 - 0.069 13.1 0.0 0.24 11.4 0.0 1.9 2 0 0 2 2 2 0 MarR family TPR_1 PF00515.28 KKK20877.1 - 3.9e-39 130.9 18.8 3.9e-05 23.3 0.2 8.8 9 0 0 9 9 9 8 Tetratricopeptide repeat STI1 PF17830.1 KKK20877.1 - 1.4e-37 127.4 13.0 9.1e-20 70.3 0.2 3.0 3 0 0 3 3 2 2 STI1 domain TPR_2 PF07719.17 KKK20877.1 - 8.9e-32 106.6 21.6 2.5e-05 24.1 0.3 9.8 9 1 1 10 10 10 6 Tetratricopeptide repeat TPR_11 PF13414.6 KKK20877.1 - 5.9e-17 61.1 17.2 6.7e-05 22.5 0.3 8.1 5 2 3 8 8 8 5 TPR repeat TPR_8 PF13181.6 KKK20877.1 - 4.5e-16 57.6 17.9 0.013 15.7 0.1 7.8 6 1 1 7 7 7 4 Tetratricopeptide repeat TPR_12 PF13424.6 KKK20877.1 - 2.3e-15 56.7 14.1 8.1e-06 26.0 1.3 6.7 6 1 2 8 8 7 4 Tetratricopeptide repeat TPR_19 PF14559.6 KKK20877.1 - 1.4e-12 47.9 13.5 0.025 15.1 0.4 7.2 5 2 2 7 7 6 5 Tetratricopeptide repeat TPR_16 PF13432.6 KKK20877.1 - 1e-11 45.3 12.6 0.016 15.8 4.0 6.6 3 2 2 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 KKK20877.1 - 3.1e-09 36.9 16.7 0.34 11.9 0.5 8.7 7 2 3 10 10 8 2 Tetratricopeptide repeat TPR_9 PF13371.6 KKK20877.1 - 3.4e-09 36.7 7.1 0.00013 22.0 0.2 4.5 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.6 KKK20877.1 - 2e-08 34.1 0.9 6.3 7.4 0.0 6.5 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 KKK20877.1 - 1.2e-07 31.3 11.5 0.013 15.4 0.0 7.8 8 1 1 9 9 8 1 Tetratricopeptide repeat TPR_10 PF13374.6 KKK20877.1 - 4.2e-07 29.6 11.1 3.8 7.5 0.1 7.1 6 1 1 7 7 7 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KKK20877.1 - 5e-05 23.3 0.7 0.16 12.1 0.0 4.8 5 0 0 5 5 5 1 Fis1 C-terminal tetratricopeptide repeat TPR_15 PF13429.6 KKK20877.1 - 0.00019 20.7 8.3 1.8 7.7 0.1 4.8 2 2 4 6 6 6 3 Tetratricopeptide repeat SHNi-TPR PF10516.9 KKK20877.1 - 0.0015 17.9 7.5 2.3 7.7 0.0 5.3 6 0 0 6 6 6 1 SHNi-TPR TPR_6 PF13174.6 KKK20877.1 - 0.0025 18.3 17.0 0.5 11.1 0.0 8.1 8 0 0 8 8 8 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KKK20877.1 - 0.012 15.8 6.4 2.7 8.3 0.1 4.4 3 3 3 6 6 6 0 Anaphase-promoting complex, cyclosome, subunit 3 NARP1 PF12569.8 KKK20877.1 - 0.017 14.0 0.1 0.017 14.0 0.1 3.9 3 2 0 4 4 4 0 NMDA receptor-regulated protein 1 DUF1840 PF08895.11 KKK20877.1 - 0.057 13.8 0.6 0.057 13.8 0.6 4.5 5 1 0 5 5 4 0 Domain of unknown function (DUF1840) TPR_20 PF14561.6 KKK20877.1 - 0.22 11.9 0.1 0.22 11.9 0.1 5.5 4 2 3 7 7 7 0 Tetratricopeptide repeat NAPRTase PF04095.16 KKK20878.1 - 2.1e-58 197.8 0.0 3.2e-58 197.2 0.0 1.3 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family NAPRTase_N PF17767.1 KKK20878.1 - 6.2e-32 110.6 0.2 1e-31 109.9 0.2 1.4 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain ING PF12998.7 KKK20879.1 - 8.2e-23 80.9 6.9 1.6e-22 80.0 6.9 1.5 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 KKK20879.1 - 7e-06 25.8 9.5 1.3e-05 25.0 9.5 1.4 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 KKK20879.1 - 0.011 16.0 0.3 0.027 14.7 0.3 1.6 1 0 0 1 1 1 0 PHD-like zinc-binding domain CDC27 PF09507.10 KKK20879.1 - 0.19 11.1 11.3 0.28 10.5 11.3 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DNA_pol_phi PF04931.13 KKK20879.1 - 2.7 6.0 7.5 4.2 5.4 7.5 1.2 1 0 0 1 1 1 0 DNA polymerase phi TFIIA PF03153.13 KKK20879.1 - 8.2 6.3 16.9 12 5.7 16.3 1.6 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Glyco_hydro_32N PF00251.20 KKK20883.1 - 1e-96 324.1 3.1 1.3e-96 323.8 3.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 KKK20883.1 - 4.9e-38 130.6 0.4 1e-37 129.6 0.4 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal Sortilin-Vps10 PF15902.5 KKK20883.1 - 0.0017 17.2 0.4 0.018 13.8 0.1 2.0 2 0 0 2 2 2 1 Sortilin, neurotensin receptor 3, BNR PF02012.20 KKK20883.1 - 0.0033 17.2 0.7 0.041 13.9 0.7 3.1 1 0 0 1 1 1 1 BNR/Asp-box repeat CHB_HEX_C PF03174.13 KKK20883.1 - 0.018 15.0 0.2 0.044 13.8 0.2 1.6 1 0 0 1 1 1 0 Chitobiase/beta-hexosaminidase C-terminal domain BNR_2 PF13088.6 KKK20883.1 - 0.024 13.9 1.8 0.26 10.5 1.8 2.2 1 1 0 1 1 1 0 BNR repeat-like domain Sec23_trunk PF04811.15 KKK20885.1 - 5.3e-57 193.2 0.0 8.6e-57 192.5 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 KKK20885.1 - 9.3e-25 86.4 0.0 2.2e-24 85.2 0.0 1.7 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 KKK20885.1 - 8.6e-18 64.9 0.0 1.6e-17 64.0 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 KKK20885.1 - 3.2e-16 59.1 6.2 6.1e-16 58.2 6.2 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 KKK20885.1 - 2e-06 27.6 0.0 4e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat SLS PF14611.6 KKK20885.1 - 0.0039 17.1 0.0 0.0073 16.1 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial inner-membrane-bound regulator DUF1678 PF07913.11 KKK20885.1 - 0.059 13.1 0.1 0.12 12.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1678) Lactamase_B_6 PF16661.5 KKK20886.1 - 2.7e-65 219.4 0.0 4.5e-65 218.7 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain CPSF100_C PF13299.6 KKK20886.1 - 9.1e-51 172.4 0.8 2.4e-50 171.1 0.0 2.1 2 0 0 2 2 2 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.8 KKK20886.1 - 2e-13 50.6 0.0 7.4e-13 48.8 0.0 2.0 2 0 0 2 2 2 1 Beta-Casp domain RMMBL PF07521.12 KKK20886.1 - 6.9e-12 45.1 0.0 4.7e-11 42.4 0.0 2.2 2 0 0 2 2 2 1 Zn-dependent metallo-hydrolase RNA specificity domain PGM_PMM_IV PF00408.20 KKK20886.1 - 0.094 12.9 0.1 0.41 10.9 0.0 2.1 2 0 0 2 2 2 0 Phosphoglucomutase/phosphomannomutase, C-terminal domain AA_permease_2 PF13520.6 KKK20887.1 - 1.8e-54 185.2 49.1 2.4e-54 184.8 49.1 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KKK20887.1 - 5.6e-14 51.6 39.4 7.3e-14 51.2 39.4 1.1 1 0 0 1 1 1 1 Amino acid permease DUF4690 PF15756.5 KKK20887.1 - 0.11 13.1 0.0 0.29 11.7 0.0 1.7 1 0 0 1 1 1 0 Small Novel Rich in Cartilage Nup88 PF10168.9 KKK20888.1 - 0.18 9.6 0.7 0.25 9.1 0.7 1.1 1 0 0 1 1 1 0 Nuclear pore component Ofd1_CTDD PF10637.9 KKK20889.1 - 5.9e-103 343.7 0.0 6.8e-99 330.4 0.0 2.3 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_4 PF13661.6 KKK20889.1 - 1.8e-26 92.6 0.0 4.5e-26 91.3 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 KKK20889.1 - 1.8e-14 54.4 0.0 5.4e-14 52.9 0.0 1.9 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily AAA_12 PF13087.6 KKK20890.1 - 1.6e-36 125.9 0.0 2.6e-36 125.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KKK20890.1 - 1.1e-22 81.1 1.4 1.2e-21 77.7 0.1 2.4 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KKK20890.1 - 2.1e-07 31.4 0.0 1.5e-06 28.6 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KKK20890.1 - 1e-06 28.6 0.1 0.0002 21.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 KKK20890.1 - 4.8e-05 23.2 0.0 0.022 14.5 0.0 3.3 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase DEAD PF00270.29 KKK20890.1 - 0.00011 22.1 0.0 0.00024 20.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase PhoH PF02562.16 KKK20890.1 - 0.0041 16.6 0.0 0.01 15.3 0.0 1.6 1 0 0 1 1 1 1 PhoH-like protein ResIII PF04851.15 KKK20890.1 - 0.035 14.1 0.0 0.17 11.8 0.0 2.1 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit DUF2075 PF09848.9 KKK20890.1 - 0.063 12.5 0.1 0.35 10.1 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Helicase_RecD PF05127.14 KKK20890.1 - 0.086 12.7 0.0 3.6 7.4 0.0 2.4 2 0 0 2 2 2 0 Helicase IstB_IS21 PF01695.17 KKK20890.1 - 0.13 12.0 0.0 0.29 10.8 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein UvrD-helicase PF00580.21 KKK20890.1 - 0.21 11.1 0.1 0.61 9.6 0.0 1.8 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain DUF3445 PF11927.8 KKK20891.1 - 1e-77 260.8 0.0 1.4e-77 260.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Fungal_trans PF04082.18 KKK20892.1 - 1.5e-18 66.8 0.6 3.8e-18 65.5 0.1 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 KKK20892.1 - 1.1e-06 28.7 10.2 0.00025 21.3 4.0 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KKK20892.1 - 4.8e-05 23.6 2.1 4.8e-05 23.6 2.1 2.7 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KKK20892.1 - 9.3e-05 23.0 8.3 0.0042 17.8 2.4 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KKK20892.1 - 0.11 12.8 0.3 0.22 11.8 0.3 1.5 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 KKK20892.1 - 1.3 8.8 9.4 2.6 7.9 0.5 2.6 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-BED PF02892.15 KKK20892.1 - 1.7 8.7 4.9 7.8 6.6 4.9 2.1 1 1 0 1 1 1 0 BED zinc finger PRP38 PF03371.15 KKK20894.1 - 6e-64 215.1 0.0 7.8e-64 214.7 0.0 1.0 1 0 0 1 1 1 1 PRP38 family DUF1566 PF07603.11 KKK20894.1 - 0.083 13.3 0.0 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1566) Pkinase PF00069.25 KKK20895.1 - 0.0013 18.2 0.0 0.0016 17.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK20895.1 - 0.077 12.3 0.0 0.092 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein tyrosine kinase WD40 PF00400.32 KKK20896.1 - 3.2e-17 62.6 1.8 0.028 15.3 0.0 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKK20896.1 - 7.3e-06 26.2 0.0 19 5.7 0.0 5.0 2 2 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain PALB2_WD40 PF16756.5 KKK20896.1 - 0.007 15.3 0.0 0.019 13.9 0.0 1.6 2 0 0 2 2 2 1 Partner and localizer of BRCA2 WD40 domain WSC PF01822.19 KKK20897.1 - 3.1e-06 27.3 7.7 3.1e-06 27.3 7.7 3.3 2 1 1 3 3 3 1 WSC domain Podoplanin PF05808.11 KKK20897.1 - 4.3e-05 23.7 8.8 9e-05 22.6 8.8 1.5 1 0 0 1 1 1 1 Podoplanin TrbL PF04610.14 KKK20897.1 - 0.0041 16.9 2.0 0.0041 16.9 2.0 1.7 2 0 0 2 2 2 1 TrbL/VirB6 plasmid conjugal transfer protein DUF4536 PF15055.6 KKK20897.1 - 0.018 15.3 1.8 0.022 15.0 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4536) Trp_oprn_chp PF09534.10 KKK20897.1 - 0.024 14.5 5.7 0.061 13.1 5.7 1.8 1 1 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) AJAP1_PANP_C PF15298.6 KKK20897.1 - 0.23 11.7 14.0 0.19 11.9 12.0 1.9 1 1 0 1 1 1 0 AJAP1/PANP C-terminus Phage_HK97_TLTM PF06120.11 KKK20897.1 - 0.9 8.7 2.9 1.5 7.9 2.3 1.7 1 1 1 2 2 2 0 Tail length tape measure protein DUF4690 PF15756.5 KKK20897.1 - 4.5 7.9 16.7 43 4.8 16.7 2.4 1 1 0 1 1 1 0 Small Novel Rich in Cartilage Herpes_pp85 PF04637.12 KKK20897.1 - 9.1 4.6 10.2 14 3.9 10.2 1.2 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Sugar_tr PF00083.24 KKK20905.1 - 1.2e-24 87.0 15.1 1.3e-24 86.9 15.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKK20905.1 - 6.5e-07 28.6 9.9 7.6e-07 28.4 9.9 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF2968 PF11180.8 KKK20919.1 - 0.00047 19.8 7.7 0.00047 19.8 7.7 4.8 3 1 2 5 5 5 1 Protein of unknown function (DUF2968) ABC_tran_CTD PF16326.5 KKK20919.1 - 0.0011 19.2 3.4 0.0011 19.2 3.4 5.5 2 1 3 5 5 5 1 ABC transporter C-terminal domain CENP-F_leu_zip PF10473.9 KKK20919.1 - 0.0026 17.8 42.3 0.12 12.4 4.5 4.3 2 1 2 4 4 4 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 EzrA PF06160.12 KKK20919.1 - 0.003 15.8 16.1 0.003 15.8 16.1 3.4 2 1 1 3 3 3 1 Septation ring formation regulator, EzrA Hemagglutinin PF00509.18 KKK20919.1 - 0.67 8.3 9.2 0.075 11.4 0.9 2.1 1 1 1 2 2 2 0 Haemagglutinin Syntaxin-6_N PF09177.11 KKK20919.1 - 1.9 9.1 29.4 0.063 13.8 8.7 4.5 3 2 0 3 3 3 0 Syntaxin 6, N-terminal Baculo_p24 PF05073.12 KKK20919.1 - 2.3 8.0 18.9 0.093 12.5 3.1 3.0 3 0 0 3 3 3 0 Baculovirus P24 capsid protein APG6_N PF17675.1 KKK20919.1 - 3.1 8.3 63.7 2.1 8.8 2.3 5.1 2 1 3 5 5 5 0 Apg6 coiled-coil region RNA_pol_Rpb5_C PF01191.19 KKK20920.1 - 3.2e-33 113.4 0.1 6.8e-33 112.4 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.14 KKK20920.1 - 4.3e-29 100.9 0.0 6.2e-29 100.4 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.12 KKK20920.1 - 0.021 14.8 0.0 0.064 13.3 0.0 1.7 2 0 0 2 2 2 0 Restriction endonuclease DHHC PF01529.20 KKK20921.1 - 0.29 11.3 3.9 1.5 8.9 0.5 2.7 2 1 1 3 3 3 0 DHHC palmitoyltransferase Glyco_hydro_3 PF00933.21 KKK20922.1 - 1.6e-56 192.0 0.0 2.7e-56 191.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 KKK20922.1 - 1.9e-56 191.3 0.4 7.2e-55 186.1 0.0 2.5 3 0 0 3 3 3 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 KKK20922.1 - 1.2e-22 79.7 0.4 4.7e-22 77.9 0.2 2.1 2 0 0 2 2 2 1 Fibronectin type III-like domain PA14 PF07691.12 KKK20922.1 - 0.0018 18.1 0.0 0.0039 17.0 0.0 1.6 1 0 0 1 1 1 1 PA14 domain CARDB PF07705.11 KKK20922.1 - 0.074 13.3 0.2 0.33 11.2 0.1 2.1 2 0 0 2 2 2 0 CARDB Aminotran_1_2 PF00155.21 KKK20923.1 - 5.5e-59 200.2 0.0 6.7e-59 199.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KKK20923.1 - 0.011 14.3 0.0 0.017 13.7 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Alliinase_C PF04864.13 KKK20923.1 - 0.058 12.2 0.0 0.084 11.7 0.0 1.1 1 0 0 1 1 1 0 Allinase GCN5L1 PF06320.13 KKK20924.1 - 9.3e-18 64.5 1.1 1.3e-17 64.0 1.1 1.1 1 0 0 1 1 1 1 GCN5-like protein 1 (GCN5L1) ParE_toxin PF05016.15 KKK20924.1 - 0.028 15.0 1.3 0.099 13.3 0.1 2.0 1 1 0 2 2 2 0 ParE toxin of type II toxin-antitoxin system, parDE Raftlin PF15250.6 KKK20924.1 - 0.083 11.6 2.5 0.097 11.4 2.5 1.0 1 0 0 1 1 1 0 Raftlin MutL_C PF08676.11 KKK20925.1 - 1.7e-23 83.0 0.0 3.9e-23 81.9 0.0 1.6 1 0 0 1 1 1 1 MutL C terminal dimerisation domain ATG7_N PF16420.5 KKK20926.1 - 5.5e-108 361.1 0.0 7.2e-108 360.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus ThiF PF00899.21 KKK20926.1 - 6.3e-47 160.0 0.0 9.7e-47 159.4 0.0 1.2 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.20 KKK20926.1 - 0.0073 16.4 0.1 0.029 14.4 0.0 1.9 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase ApbA PF02558.16 KKK20926.1 - 0.11 12.2 0.0 0.31 10.7 0.0 1.6 1 1 1 2 2 2 0 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.19 KKK20926.1 - 0.13 11.6 0.0 0.58 9.5 0.0 1.9 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FtsJ PF01728.19 KKK20927.1 - 3.6e-34 118.4 0.2 2.1e-24 86.6 0.0 2.7 3 0 0 3 3 3 2 FtsJ-like methyltransferase GAS PF13851.6 KKK20927.1 - 2.7 7.3 30.2 0.02 14.3 11.5 3.3 2 1 2 4 4 4 0 Growth-arrest specific micro-tubule binding OST3_OST6 PF04756.13 KKK20928.1 - 1.2e-24 87.2 0.0 1.8e-24 86.6 0.0 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family OST3_OST6 PF04756.13 KKK20929.1 - 4.1e-69 233.2 0.4 4.6e-69 233.0 0.4 1.0 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family HXXEE PF13787.6 KKK20929.1 - 0.023 15.5 0.9 0.023 15.5 0.9 2.0 1 1 1 2 2 2 0 Protein of unknown function with HXXEE motif DEAD PF00270.29 KKK20930.1 - 8.5e-51 172.2 0.0 2e-50 171.0 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KKK20930.1 - 1.4e-33 115.6 0.5 1.9e-30 105.5 0.1 2.4 2 1 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.15 KKK20930.1 - 1.2e-08 35.2 0.0 3.1e-08 33.8 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KKK20930.1 - 4.8e-06 26.0 0.1 8e-06 25.2 0.1 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase CMS1 PF14617.6 KKK20930.1 - 0.0064 15.9 0.1 0.0064 15.9 0.1 2.3 3 1 0 3 3 3 1 U3-containing 90S pre-ribosomal complex subunit UTP25 PF06862.12 KKK20930.1 - 0.14 10.9 0.2 8.3 5.0 0.0 2.3 2 1 0 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Fungal_trans PF04082.18 KKK20931.1 - 8.8e-09 34.8 0.0 2.5e-08 33.3 0.0 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Med14 PF08638.11 KKK20932.1 - 1.2e-67 227.1 0.0 2e-67 226.3 0.0 1.4 1 0 0 1 1 1 1 Mediator complex subunit MED14 ATG22 PF11700.8 KKK20933.1 - 2.5e-212 705.7 15.7 2.8e-212 705.6 15.7 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.16 KKK20933.1 - 1.2e-11 44.2 39.7 4.3e-11 42.3 12.0 3.1 3 0 0 3 3 3 3 Major Facilitator Superfamily Mfp-3 PF04202.13 KKK20933.1 - 0.074 13.4 0.1 15 6.1 0.3 2.6 2 0 0 2 2 2 0 Foot protein 3 Thioredoxin PF00085.20 KKK20934.1 - 4.7e-61 203.2 3.7 6.6e-31 106.3 0.2 4.4 4 1 0 4 4 4 3 Thioredoxin Thioredoxin_6 PF13848.6 KKK20934.1 - 5.1e-47 160.2 0.8 1.5e-36 126.0 0.2 3.4 2 1 1 3 3 3 2 Thioredoxin-like domain Calsequestrin PF01216.17 KKK20934.1 - 5e-11 42.3 1.7 1.7e-10 40.5 1.7 1.8 1 1 0 1 1 1 1 Calsequestrin Thioredoxin_8 PF13905.6 KKK20934.1 - 7e-08 32.7 0.0 0.011 16.0 0.0 3.3 3 0 0 3 3 3 2 Thioredoxin-like Thioredoxin_7 PF13899.6 KKK20934.1 - 1.3e-06 28.5 0.0 0.051 13.8 0.0 2.8 2 0 0 2 2 2 2 Thioredoxin-like OST3_OST6 PF04756.13 KKK20934.1 - 1.4e-06 27.9 0.3 0.0047 16.3 0.0 3.3 2 1 1 3 3 3 2 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 KKK20934.1 - 2.1e-06 27.7 1.2 0.012 15.6 0.1 2.9 3 0 0 3 3 3 2 AhpC/TSA family Thioredoxin_2 PF13098.6 KKK20934.1 - 3.8e-06 27.3 1.4 0.11 12.9 0.1 3.4 3 1 0 3 3 3 2 Thioredoxin-like domain Redoxin PF08534.10 KKK20934.1 - 1.3e-05 25.0 2.2 0.79 9.4 0.0 3.4 3 0 0 3 3 3 2 Redoxin Glycos_trans_3N PF02885.17 KKK20934.1 - 0.04 13.8 0.0 0.13 12.1 0.0 1.9 1 0 0 1 1 1 0 Glycosyl transferase family, helical bundle domain UDG PF03167.19 KKK20935.1 - 1.3e-21 77.2 0.1 2.2e-21 76.4 0.1 1.3 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily DWNN PF08783.11 KKK20936.1 - 5.3e-34 116.3 0.5 1.1e-33 115.4 0.1 1.8 2 0 0 2 2 2 1 DWNN domain zf-CCHC_2 PF13696.6 KKK20936.1 - 2.6e-08 33.5 5.0 6e-08 32.4 5.0 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 KKK20936.1 - 0.0017 18.3 0.7 0.0038 17.2 0.7 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-C3HC4_2 PF13923.6 KKK20936.1 - 0.003 17.4 8.6 0.0064 16.3 8.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) CpXC PF14353.6 KKK20936.1 - 0.044 13.8 0.1 0.11 12.5 0.1 1.7 1 0 0 1 1 1 0 CpXC protein zf-Nse PF11789.8 KKK20936.1 - 0.17 11.7 3.7 0.38 10.6 3.7 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_2 PF13639.6 KKK20936.1 - 0.31 11.4 6.3 0.7 10.3 6.3 1.6 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4 PF00097.25 KKK20936.1 - 2 8.3 8.7 4.6 7.2 8.7 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KKK20936.1 - 3.6 7.6 11.4 0.27 11.2 5.2 2.2 2 0 0 2 2 2 0 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KKK20936.1 - 7.9 6.7 9.6 20 5.4 9.6 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Yippee-Mis18 PF03226.14 KKK20937.1 - 1.1e-24 86.6 0.1 1.6e-24 86.2 0.1 1.2 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RIG-I_C-RD PF11648.8 KKK20937.1 - 0.011 16.0 0.5 0.3 11.3 0.0 2.1 2 0 0 2 2 2 0 C-terminal domain of RIG-I Transp_Tc5_C PF04236.15 KKK20937.1 - 0.024 15.0 0.4 4.6 7.7 0.2 2.4 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain zf-ribbon_3 PF13248.6 KKK20937.1 - 0.058 12.8 0.1 0.058 12.8 0.1 1.9 2 0 0 2 2 2 0 zinc-ribbon domain Lar_restr_allev PF14354.6 KKK20937.1 - 0.11 12.9 0.1 26 5.3 0.0 2.6 3 0 0 3 3 3 0 Restriction alleviation protein Lar SHNi-TPR PF10516.9 KKK20938.1 - 1.2e-17 63.0 1.9 1.6e-16 59.5 0.2 2.8 2 0 0 2 2 2 1 SHNi-TPR TPR_12 PF13424.6 KKK20938.1 - 6.4e-06 26.4 8.1 0.013 15.7 1.9 3.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 KKK20938.1 - 0.0019 17.9 2.4 0.44 10.4 1.2 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat CCDC-167 PF15188.6 KKK20938.1 - 0.013 15.9 1.5 0.013 15.9 1.5 2.0 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 TPR_10 PF13374.6 KKK20938.1 - 0.02 14.8 3.9 5.8 6.9 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 KKK20938.1 - 0.034 13.8 7.1 11 5.7 0.0 4.3 5 0 0 5 5 5 0 TPR repeat TPR_8 PF13181.6 KKK20938.1 - 0.05 13.8 5.7 4.4 7.8 1.6 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat MIT PF04212.18 KKK20938.1 - 0.059 13.5 4.6 0.05 13.7 1.7 2.4 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain TetR_C_32 PF09209.11 KKK20938.1 - 0.11 12.4 0.0 0.96 9.4 0.0 2.2 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain TPR_2 PF07719.17 KKK20938.1 - 0.23 11.7 11.9 3 8.2 1.7 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.6 KKK20938.1 - 0.45 11.1 5.8 1.2 9.7 2.7 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 KKK20938.1 - 0.78 10.4 6.8 21 5.9 0.1 3.0 2 1 0 2 2 2 0 Tetratricopeptide repeat DNA_pol_E_B PF04042.16 KKK20939.1 - 8.9e-52 175.5 0.0 1.2e-51 175.1 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B dCMP_cyt_deam_1 PF00383.23 KKK20940.1 - 8.5e-28 96.2 1.5 1.4e-27 95.5 1.5 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KKK20940.1 - 1.4e-10 41.0 0.2 2.6e-10 40.2 0.2 1.4 1 0 0 1 1 1 1 MafB19-like deaminase AAA_18 PF13238.6 KKK20940.1 - 0.0074 16.8 0.0 0.028 15.0 0.0 1.9 2 1 0 2 2 2 1 AAA domain CoaE PF01121.20 KKK20940.1 - 0.027 14.1 0.0 0.05 13.3 0.0 1.4 1 0 0 1 1 1 0 Dephospho-CoA kinase SNAD4 PF18750.1 KKK20940.1 - 0.029 14.5 0.3 0.45 10.7 0.1 2.4 2 0 0 2 2 2 0 Secreted Novel AID/APOBEC-like Deaminase 4 His_biosynth PF00977.21 KKK20941.1 - 1.1e-48 165.7 0.8 4.4e-48 163.7 0.8 2.0 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.28 KKK20941.1 - 7.3e-24 84.6 0.0 1.3e-23 83.7 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I SNO PF01174.19 KKK20941.1 - 6e-12 45.8 0.0 2.9e-09 37.0 0.0 2.2 2 0 0 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.14 KKK20941.1 - 8.8e-08 32.0 0.0 2.2e-07 30.7 0.0 1.7 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_C26 PF07722.13 KKK20941.1 - 0.004 16.9 0.0 0.012 15.4 0.0 1.8 1 1 0 1 1 1 1 Peptidase C26 Dus PF01207.17 KKK20941.1 - 0.0089 15.1 0.0 0.021 14.0 0.0 1.5 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) ThiG PF05690.14 KKK20941.1 - 0.22 10.8 2.0 0.17 11.2 0.2 1.7 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG Dynamin_N PF00350.23 KKK20944.1 - 2.4e-11 44.0 0.0 1.1e-10 41.8 0.0 2.2 1 1 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 KKK20944.1 - 6.1e-06 26.3 0.0 0.00014 22.0 0.0 2.8 2 1 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KKK20944.1 - 3.4e-05 23.8 0.1 0.00016 21.6 0.1 2.2 2 0 0 2 2 2 1 RsgA GTPase ABC_tran PF00005.27 KKK20944.1 - 0.00034 21.1 0.2 0.0044 17.5 0.0 2.7 2 0 0 2 2 2 1 ABC transporter AAA_16 PF13191.6 KKK20944.1 - 0.00037 20.9 11.5 0.00066 20.1 0.0 3.9 3 1 0 4 4 4 1 AAA ATPase domain Roc PF08477.13 KKK20944.1 - 0.0052 17.0 0.0 0.015 15.5 0.0 1.9 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_18 PF13238.6 KKK20944.1 - 0.02 15.4 0.2 0.094 13.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 KKK20944.1 - 0.049 13.9 1.4 0.16 12.3 0.0 2.5 3 0 0 3 3 3 0 AAA domain AAA_29 PF13555.6 KKK20944.1 - 0.06 13.1 0.1 0.14 11.9 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain GTP_EFTU PF00009.27 KKK20944.1 - 0.15 11.6 0.0 0.73 9.3 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Sec15 PF04091.12 KKK20944.1 - 0.39 10.1 3.1 0.4 10.0 1.2 1.9 1 1 1 2 2 2 0 Exocyst complex subunit Sec15-like AAA_23 PF13476.6 KKK20944.1 - 0.93 10.0 9.6 5.6 7.4 0.0 3.9 3 1 1 4 4 4 0 AAA domain Rx_N PF18052.1 KKK20944.1 - 0.94 9.8 6.4 0.71 10.2 0.6 3.0 2 0 0 2 2 2 0 Rx N-terminal domain SesA PF17107.5 KKK20944.1 - 7 6.9 7.0 14 5.9 1.0 3.1 3 0 0 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases UPF0016 PF01169.19 KKK20945.1 - 2.7e-41 139.8 26.0 1.5e-21 76.5 9.8 2.2 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 DUF3357 PF11837.8 KKK20945.1 - 0.7 10.4 6.2 4.6 7.8 0.3 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF3357) DUF2070 PF09843.9 KKK20945.1 - 1.9 6.7 5.8 0.11 10.8 0.5 1.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2070) MFS_1 PF07690.16 KKK20946.1 - 2e-40 138.8 15.3 2e-40 138.8 15.3 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KKK20946.1 - 7.3e-15 54.8 5.2 7.3e-15 54.8 5.2 3.0 2 1 0 3 3 3 1 Sugar (and other) transporter TM140 PF14985.6 KKK20946.1 - 0.03 13.9 0.6 0.11 12.1 0.6 1.9 1 0 0 1 1 1 0 TM140 protein family MFA1_2 PF17317.2 KKK20946.1 - 0.55 10.0 1.8 0.57 10.0 0.0 2.0 2 0 0 2 2 2 0 Mating hormone A-factor 1&2 Podoplanin PF05808.11 KKK20947.1 - 0.0015 18.6 0.0 0.0015 18.6 0.0 1.7 2 0 0 2 2 2 1 Podoplanin Cu_bind_like PF02298.17 KKK20947.1 - 0.03 14.3 0.4 0.11 12.5 0.4 2.1 1 1 0 1 1 1 0 Plastocyanin-like domain Amnionless PF14828.6 KKK20947.1 - 0.043 12.6 0.0 0.067 12.0 0.0 1.2 1 0 0 1 1 1 0 Amnionless VSP PF03302.13 KKK20947.1 - 0.17 10.7 1.8 0.29 10.0 1.8 1.3 1 0 0 1 1 1 0 Giardia variant-specific surface protein MGC-24 PF05283.11 KKK20947.1 - 0.49 10.9 6.5 0.22 12.0 0.3 2.3 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin TPPK_C PF12555.8 KKK20947.1 - 0.55 10.3 3.8 1.2 9.2 3.8 1.5 1 0 0 1 1 1 0 Thiamine pyrophosphokinase C terminal Plasmodium_Vir PF05795.11 KKK20947.1 - 0.64 9.4 1.7 0.37 10.2 0.1 1.6 2 0 0 2 2 2 0 Plasmodium vivax Vir protein SSP160 PF06933.11 KKK20947.1 - 3.3 5.8 14.3 1.7 6.8 4.9 2.2 2 0 0 2 2 2 0 Special lobe-specific silk protein SSP160 DUF5562 PF17717.1 KKK20947.1 - 4.7 7.1 13.0 1.2 9.1 1.7 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5562) MFS_1 PF07690.16 KKK20948.1 - 0.00018 20.6 36.2 0.00021 20.4 29.0 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 KKK20955.1 - 8.7e-08 31.5 12.9 8.7e-08 31.5 12.9 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KKK20955.1 - 5e-05 21.9 8.7 6.4e-05 21.6 8.7 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) TMEM208_SND2 PF05620.11 KKK20955.1 - 0.023 14.5 6.9 0.057 13.2 7.0 1.6 1 1 0 1 1 1 0 SRP-independent targeting protein 2/TMEM208 DUF3546 PF12066.8 KKK20963.1 - 2.9e-32 111.1 1.0 2.9e-32 111.1 1.0 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF3546) ARS2 PF04959.13 KKK20963.1 - 8.7e-14 52.4 0.0 3.1e-13 50.5 0.0 2.0 1 0 0 1 1 1 1 Arsenite-resistance protein 2 DUF4187 PF13821.6 KKK20963.1 - 9.5e-13 47.7 0.9 2.1e-12 46.6 0.9 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) Zn_clus PF00172.18 KKK20964.1 - 2.6e-06 27.4 9.9 6.1e-06 26.2 9.9 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KKK20964.1 - 0.00013 21.1 1.3 0.00022 20.4 1.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain TrmE_N PF10396.9 KKK20965.1 - 8.8e-37 125.9 0.0 2.2e-36 124.6 0.0 1.7 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus MnmE_helical PF12631.7 KKK20965.1 - 3.4e-26 92.7 0.0 1.5e-25 90.6 0.0 1.8 1 1 0 1 1 1 1 MnmE helical domain MMR_HSR1 PF01926.23 KKK20965.1 - 1e-17 64.2 0.0 1.6e-17 63.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KKK20965.1 - 7.1e-06 25.7 0.0 0.00034 20.2 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 KKK20965.1 - 2.3e-05 24.0 0.0 0.00013 21.6 0.0 2.1 2 1 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 KKK20965.1 - 0.00015 21.9 0.0 0.00023 21.3 0.0 1.3 1 0 0 1 1 1 1 Dynamin family Glyco_hydro_3_C PF01915.22 KKK20965.1 - 0.0014 18.6 0.0 0.002 18.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain AAA_24 PF13479.6 KKK20965.1 - 0.0025 17.6 0.0 0.008 15.9 0.0 1.8 2 0 0 2 2 2 1 AAA domain Roc PF08477.13 KKK20965.1 - 0.084 13.1 0.1 0.21 11.8 0.0 1.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Ank_2 PF12796.7 KKK20966.1 - 7.1e-63 209.2 14.1 1.5e-15 57.5 0.1 7.4 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KKK20966.1 - 3.8e-52 174.0 18.3 1.1e-08 35.4 0.1 8.3 6 2 1 8 8 8 8 Ankyrin repeats (many copies) Ank PF00023.30 KKK20966.1 - 3.3e-46 153.8 24.6 1.6e-05 25.1 0.0 13.7 13 0 0 13 13 13 9 Ankyrin repeat Ank_3 PF13606.6 KKK20966.1 - 1.6e-40 132.4 15.4 0.0015 18.9 0.0 14.1 14 0 0 14 14 14 8 Ankyrin repeat Ank_5 PF13857.6 KKK20966.1 - 1.2e-33 114.7 19.9 6.5e-06 26.3 0.3 11.0 3 3 9 12 12 12 8 Ankyrin repeats (many copies) Helo_like_N PF17111.5 KKK20966.1 - 0.0035 16.7 0.2 0.0065 15.9 0.2 1.5 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins Aconitase PF00330.20 KKK20967.1 - 1e-110 370.9 0.2 6.3e-110 368.3 0.2 1.9 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KKK20967.1 - 5.5e-26 91.4 0.0 9.1e-26 90.7 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain NAD_binding_1 PF00175.21 KKK20967.1 - 1.5e-07 32.1 0.0 0.0051 17.4 0.0 2.5 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KKK20967.1 - 4.3e-05 23.8 0.0 9.1e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 KKK20967.1 - 0.009 16.1 0.0 0.021 14.9 0.0 1.6 1 0 0 1 1 1 1 Ferric reductase NAD binding domain AA_permease_2 PF13520.6 KKK20968.1 - 2.2e-62 211.3 40.7 3.4e-62 210.7 40.7 1.3 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KKK20968.1 - 1.2e-26 93.4 23.2 1.2e-26 93.4 23.2 2.2 2 0 0 2 2 2 2 Amino acid permease NADHdeh_related PF10125.9 KKK20968.1 - 0.011 15.1 1.7 0.011 15.1 1.7 1.7 2 0 0 2 2 2 0 NADH dehydrogenase I, subunit N related protein MFS_1 PF07690.16 KKK20999.1 - 3.6e-26 91.9 32.5 1.6e-23 83.3 23.8 2.8 2 1 1 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.24 KKK20999.1 - 1.7e-08 33.8 13.3 1.7e-08 33.8 13.3 3.0 2 1 0 3 3 3 2 Sugar (and other) transporter MFS_1 PF07690.16 KKK21000.1 - 7.5e-28 97.5 37.7 1.3e-23 83.6 21.4 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KKK21000.1 - 3.2e-15 55.9 5.6 5.6e-14 51.9 5.6 2.5 1 1 0 1 1 1 1 Sugar (and other) transporter Methyltransf_25 PF13649.6 KKK21001.1 - 1.5e-16 60.9 0.0 4.3e-16 59.4 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KKK21001.1 - 4.4e-15 56.1 0.0 8.3e-15 55.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KKK21001.1 - 6.3e-13 49.3 0.0 1e-12 48.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KKK21001.1 - 8.5e-13 48.5 0.0 1.2e-12 48.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KKK21001.1 - 1.4e-10 41.2 0.0 2e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KKK21001.1 - 1.1e-08 34.9 0.0 1.5e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.19 KKK21001.1 - 5.2e-06 26.4 0.0 1.3e-05 25.0 0.0 1.8 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_9 PF08003.11 KKK21001.1 - 1.5e-05 24.1 0.0 2.4e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Ubie_methyltran PF01209.18 KKK21001.1 - 2.2e-05 23.9 0.0 3.2e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family RrnaAD PF00398.20 KKK21001.1 - 2.9e-05 23.3 0.0 0.00052 19.2 0.0 2.1 1 1 0 1 1 1 1 Ribosomal RNA adenine dimethylase NodS PF05401.11 KKK21001.1 - 4.9e-05 23.0 0.0 8.8e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Nodulation protein S (NodS) PrmA PF06325.13 KKK21001.1 - 0.00022 20.7 0.0 0.00033 20.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) DREV PF05219.12 KKK21001.1 - 0.00073 18.7 0.0 0.001 18.2 0.0 1.3 1 0 0 1 1 1 1 DREV methyltransferase CMAS PF02353.20 KKK21001.1 - 0.0061 15.9 0.0 0.0079 15.5 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase TPMT PF05724.11 KKK21001.1 - 0.0081 15.8 0.0 0.13 11.9 0.0 2.2 2 0 0 2 2 2 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_32 PF13679.6 KKK21001.1 - 0.049 13.6 0.0 0.084 12.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain tRNA_U5-meth_tr PF05958.11 KKK21001.1 - 0.12 11.4 0.0 0.16 10.9 0.0 1.2 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase DHHC PF01529.20 KKK21002.1 - 1.2e-30 106.4 4.1 1.2e-30 106.4 4.1 1.9 2 0 0 2 2 2 1 DHHC palmitoyltransferase DNA_mis_repair PF01119.19 KKK21003.1 - 4.7e-11 42.4 0.0 1e-10 41.3 0.0 1.6 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 KKK21003.1 - 7.1e-09 35.6 0.0 2e-08 34.1 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 KKK21003.1 - 2.2e-08 34.6 0.1 5.4e-08 33.3 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Cep57_CLD PF14073.6 KKK21003.1 - 0.062 13.3 3.4 0.13 12.3 3.4 1.5 1 0 0 1 1 1 0 Centrosome localisation domain of Cep57 Mito_carr PF00153.27 KKK21003.1 - 0.078 12.9 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 Mitochondrial carrier protein DUF202 PF02656.15 KKK21005.1 - 3e-16 59.6 0.4 6e-16 58.7 0.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF202) MBOAT_2 PF13813.6 KKK21006.1 - 1.5e-18 66.8 5.1 3.2e-18 65.8 5.1 1.6 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Imp-YgjV PF10688.9 KKK21006.1 - 0.48 10.2 7.6 0.067 13.0 2.8 2.0 2 0 0 2 2 2 0 Bacterial inner membrane protein SBF_like PF13593.6 KKK21007.1 - 4.6e-89 298.8 19.1 5.3e-89 298.6 19.1 1.0 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) SBF PF01758.16 KKK21007.1 - 7.2e-11 42.1 4.7 7.2e-11 42.1 4.7 1.9 1 1 1 2 2 2 1 Sodium Bile acid symporter family Mito_carr PF00153.27 KKK21008.1 - 2.1e-66 219.9 2.7 1.3e-22 79.5 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein bZIP_2 PF07716.15 KKK21009.1 - 2e-11 43.8 16.6 2e-11 43.8 16.6 2.5 1 1 1 2 2 2 2 Basic region leucine zipper bZIP_1 PF00170.21 KKK21009.1 - 2.1e-06 27.7 18.6 4.2e-06 26.8 18.6 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 KKK21009.1 - 0.00047 20.6 14.9 0.00099 19.6 14.9 1.5 1 0 0 1 1 1 1 bZIP Maf transcription factor APG6_N PF17675.1 KKK21009.1 - 0.038 14.5 13.8 0.078 13.5 13.8 1.5 1 0 0 1 1 1 0 Apg6 coiled-coil region Spc24 PF08286.11 KKK21009.1 - 0.052 13.8 0.6 0.11 12.7 0.6 1.5 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 DUF3638 PF12340.8 KKK21024.1 - 6.8e-80 267.6 1.8 1.1e-79 267.0 1.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.8 KKK21024.1 - 8.9e-15 53.8 0.1 1.6e-14 53.0 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) IQ PF00612.27 KKK21024.1 - 0.45 10.5 2.4 18 5.5 0.1 3.2 3 0 0 3 3 3 0 IQ calmodulin-binding motif Cryptochrome_C PF12546.8 KKK21025.1 - 0.34 11.5 2.9 1 10.0 2.8 1.8 1 1 0 1 1 1 0 Blue/Ultraviolet sensing protein C terminal MFS_1 PF07690.16 KKK21026.1 - 6.7e-33 114.1 26.8 6.7e-33 114.1 26.8 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 KKK21026.1 - 0.00032 20.1 1.0 0.00032 20.1 1.0 1.7 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB adh_short_C2 PF13561.6 KKK21027.1 - 4.1e-47 160.7 0.0 8.9e-47 159.6 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KKK21027.1 - 5.8e-38 130.3 0.0 8.2e-38 129.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KKK21027.1 - 1.9e-05 24.7 0.0 0.00013 21.9 0.0 2.0 1 1 0 1 1 1 1 KR domain Kp4 PF09044.10 KKK21027.1 - 0.011 15.8 0.0 0.027 14.6 0.0 1.6 1 0 0 1 1 1 0 Kp4 DAO PF01266.24 KKK21028.1 - 3.3e-35 122.3 0.0 3.8e-35 122.1 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KKK21028.1 - 0.00067 18.9 0.0 0.00097 18.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KKK21028.1 - 0.0032 17.7 0.3 0.0081 16.4 0.3 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KKK21028.1 - 0.021 14.0 0.1 0.021 14.0 0.1 1.7 2 0 0 2 2 2 0 Thi4 family Pyr_redox PF00070.27 KKK21028.1 - 0.028 15.0 0.1 0.15 12.7 0.1 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KKK21028.1 - 0.036 13.3 0.0 0.058 12.6 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KKK21028.1 - 0.055 12.7 0.3 0.088 12.0 0.3 1.3 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.12 KKK21028.1 - 0.089 11.8 0.0 2.4 7.1 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein Aa_trans PF01490.18 KKK21029.1 - 5.7e-28 97.8 44.0 2.1e-14 53.1 12.9 2.0 1 1 0 2 2 2 2 Transmembrane amino acid transporter protein K1 PF02960.14 KKK21029.1 - 1.1 9.4 0.0 1.1 9.4 0.0 2.9 3 0 0 3 3 3 0 K1 glycoprotein Aldolase_II PF00596.21 KKK21030.1 - 9.4e-35 120.2 0.0 1.1e-34 120.0 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Fer2_4 PF13510.6 KKK21030.1 - 0.14 12.3 0.3 11 6.2 0.1 2.4 2 1 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain Zn_clus PF00172.18 KKK21031.1 - 3.3e-07 30.3 10.8 7.6e-07 29.1 10.8 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GIT_CC PF16559.5 KKK21031.1 - 0.033 14.1 0.3 0.14 12.0 0.0 2.0 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor DIOX_N PF14226.6 KKK21032.1 - 2.4e-29 102.5 0.0 3.8e-29 101.8 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KKK21032.1 - 2.3e-17 63.3 0.0 4.1e-17 62.5 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_2 PF13532.6 KKK21034.1 - 3.1e-29 102.6 0.0 2.3e-28 99.7 0.0 2.0 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily ADH_zinc_N PF00107.26 KKK21035.1 - 7.6e-12 45.3 0.1 3.1e-11 43.4 0.0 2.2 2 1 1 3 3 3 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KKK21035.1 - 0.00016 21.5 0.1 0.00031 20.6 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain FAD_binding_3 PF01494.19 KKK21036.1 - 2.2e-19 70.0 0.1 1.2e-18 67.5 0.1 2.2 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KKK21036.1 - 8.2e-06 25.3 0.0 0.077 12.2 0.0 2.4 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KKK21036.1 - 0.00022 21.4 0.0 0.00057 20.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KKK21036.1 - 0.00031 21.3 0.0 0.23 12.0 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KKK21036.1 - 0.00073 18.9 0.0 0.2 10.9 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KKK21036.1 - 0.0036 16.4 0.1 0.09 11.8 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain Amino_oxidase PF01593.24 KKK21036.1 - 0.0072 15.7 0.0 0.28 10.4 0.0 2.6 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase Peptidase_M35 PF02102.15 KKK21037.1 - 1.4e-58 198.5 7.7 1.9e-58 198.1 7.7 1.1 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.6 KKK21037.1 - 3.7e-31 108.6 4.4 5.9e-31 108.0 4.4 1.3 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase 2OG-FeII_Oxy_2 PF13532.6 KKK21038.1 - 4.1e-31 108.7 0.0 8.2e-31 107.7 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PIG-L PF02585.17 KKK21039.1 - 1.7e-19 70.8 0.2 2.4e-19 70.2 0.2 1.3 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase WD40 PF00400.32 KKK21045.1 - 2.2e-13 50.5 18.5 5.9e-06 26.9 0.5 6.2 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKK21045.1 - 3.8e-08 33.5 0.1 1.9 8.9 0.0 4.9 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KKK21045.1 - 0.001 19.0 0.0 0.012 15.5 0.0 2.4 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A zf-C2H2_aberr PF17017.5 KKK21045.1 - 0.013 15.7 0.2 0.038 14.2 0.0 1.8 2 0 0 2 2 2 0 Aberrant zinc-finger NFACT-R_1 PF05670.13 KKK21045.1 - 0.03 15.0 0.0 0.34 11.6 0.0 2.4 2 0 0 2 2 2 0 NFACT protein RNA binding domain zf-rbx1 PF12678.7 KKK21045.1 - 3.2 8.1 11.5 0.066 13.5 2.1 2.5 2 0 0 2 2 2 0 RING-H2 zinc finger domain Zn_ribbon_17 PF17120.5 KKK21045.1 - 4 7.1 10.9 9.3 6.0 10.1 2.0 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type FYVE_2 PF02318.16 KKK21045.1 - 6.8 6.9 5.4 7.4 6.8 2.4 2.2 2 0 0 2 2 2 0 FYVE-type zinc finger PRK PF00485.18 KKK21052.1 - 1e-08 35.2 0.0 1.3e-08 34.9 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 KKK21052.1 - 3.1e-06 27.8 0.0 1e-05 26.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KKK21052.1 - 0.00014 22.3 0.6 0.00033 21.1 0.4 1.7 1 1 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.12 KKK21052.1 - 0.00022 20.6 0.5 0.00052 19.3 0.1 1.7 2 0 0 2 2 2 1 Zeta toxin AAA_22 PF13401.6 KKK21052.1 - 0.00067 19.9 0.0 0.006 16.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KKK21052.1 - 0.00077 19.6 3.3 0.048 13.8 3.3 2.8 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 KKK21052.1 - 0.001 18.8 0.2 1.2 8.8 0.0 2.2 2 0 0 2 2 2 2 Thymidylate kinase SRP54 PF00448.22 KKK21052.1 - 0.0028 17.3 0.0 0.0043 16.7 0.0 1.2 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA PF00004.29 KKK21052.1 - 0.0033 17.8 0.1 0.0078 16.6 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 KKK21052.1 - 0.019 14.7 0.2 0.034 13.9 0.2 1.3 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 KKK21052.1 - 0.019 14.2 0.0 0.034 13.3 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain MeaB PF03308.16 KKK21052.1 - 0.023 13.7 0.1 0.037 13.0 0.1 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_17 PF13207.6 KKK21052.1 - 0.03 14.7 0.1 0.68 10.4 0.1 2.4 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.20 KKK21052.1 - 0.035 14.0 0.1 0.19 11.6 0.0 2.0 2 0 0 2 2 2 0 Adenylylsulphate kinase 6PF2K PF01591.18 KKK21052.1 - 0.067 12.5 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase AAA_11 PF13086.6 KKK21052.1 - 0.15 11.8 0.0 0.19 11.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain SKI PF01202.22 KKK21052.1 - 0.33 11.1 1.5 12 6.0 0.1 2.3 2 0 0 2 2 2 0 Shikimate kinase ADH_N PF08240.12 KKK21053.1 - 1.6e-09 37.6 0.0 2.8e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KKK21053.1 - 4.7e-06 26.6 0.0 1.2e-05 25.3 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 KKK21053.1 - 0.00047 20.0 0.0 0.00086 19.2 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase Fungal_trans PF04082.18 KKK21054.1 - 6.2e-16 58.2 0.1 1.5e-15 57.0 0.0 1.6 1 1 1 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK21055.1 - 0.0063 16.6 5.6 0.043 14.0 5.6 2.2 1 1 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NmrA PF05368.13 KKK21056.1 - 3.5e-15 56.2 0.0 4.7e-15 55.8 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KKK21056.1 - 1.7e-14 54.1 0.0 5.6e-14 52.4 0.0 2.0 2 1 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 KKK21056.1 - 2.5e-09 37.0 0.1 5.7e-09 35.8 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KKK21056.1 - 1.7e-05 24.9 0.1 2.3e-05 24.4 0.1 1.2 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 KKK21056.1 - 3.6e-05 24.0 0.1 5.9e-05 23.3 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_4 PF07993.12 KKK21056.1 - 0.00048 19.4 0.0 0.00069 18.9 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Shikimate_DH PF01488.20 KKK21056.1 - 0.0058 16.7 0.1 0.01 15.9 0.1 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase GDP_Man_Dehyd PF16363.5 KKK21056.1 - 0.0067 15.9 0.0 0.032 13.6 0.1 1.9 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase CbiJ PF02571.14 KKK21056.1 - 0.0072 15.8 0.0 0.01 15.3 0.0 1.2 1 0 0 1 1 1 1 Precorrin-6x reductase CbiJ/CobK 3Beta_HSD PF01073.19 KKK21056.1 - 0.013 14.5 0.1 0.024 13.6 0.1 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 KKK21056.1 - 0.018 14.5 0.1 0.032 13.7 0.1 1.4 1 0 0 1 1 1 0 short chain dehydrogenase RmlD_sub_bind PF04321.17 KKK21056.1 - 0.027 13.6 0.1 0.044 12.9 0.1 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 KKK21056.1 - 0.031 13.4 0.3 0.071 12.2 0.3 1.5 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein TrkA_N PF02254.18 KKK21056.1 - 0.039 14.2 0.1 0.11 12.8 0.0 1.7 2 0 0 2 2 2 0 TrkA-N domain Semialdhyde_dh PF01118.24 KKK21056.1 - 0.068 13.6 0.1 0.16 12.4 0.1 1.7 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 KKK21056.1 - 0.21 11.7 0.6 0.44 10.7 0.5 1.6 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Aminotran_5 PF00266.19 KKK21057.1 - 4.1e-30 105.0 0.0 1.5e-19 70.2 0.0 2.0 1 1 1 2 2 2 2 Aminotransferase class-V ApbE PF02424.15 KKK21057.1 - 0.11 12.0 0.1 0.36 10.3 0.0 1.7 2 0 0 2 2 2 0 ApbE family HEAT_EZ PF13513.6 KKK21058.1 - 5.9e-14 52.2 1.9 2.3e-10 40.7 0.2 5.2 4 2 2 6 6 6 2 HEAT-like repeat HEAT PF02985.22 KKK21058.1 - 1.2e-12 46.9 15.3 0.00015 21.8 0.2 8.8 9 1 0 9 9 9 2 HEAT repeat IBN_N PF03810.19 KKK21058.1 - 1.5e-09 37.7 2.4 1.7e-08 34.3 0.2 3.6 4 0 0 4 4 4 1 Importin-beta N-terminal domain HEAT_2 PF13646.6 KKK21058.1 - 9.5e-08 32.3 8.5 0.0006 20.2 0.7 6.2 3 2 4 7 7 7 4 HEAT repeats CLASP_N PF12348.8 KKK21058.1 - 2e-05 24.3 2.3 1.6 8.2 0.0 5.2 3 1 2 5 5 5 2 CLASP N terminal HEAT_PBS PF03130.16 KKK21058.1 - 0.00043 20.7 0.0 8.1 7.4 0.0 5.3 5 0 0 5 5 5 1 PBS lyase HEAT-like repeat Ecm29 PF13001.7 KKK21058.1 - 0.0016 17.2 0.4 0.84 8.2 0.0 3.5 3 1 1 4 4 4 2 Proteasome stabiliser Cnd1 PF12717.7 KKK21058.1 - 0.0018 18.4 0.7 0.02 14.9 0.0 3.0 2 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 Arm PF00514.23 KKK21058.1 - 0.011 15.8 1.9 6 7.1 0.0 3.5 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat Dopey_N PF04118.14 KKK21058.1 - 0.03 13.4 0.4 0.13 11.3 0.1 2.2 3 0 0 3 3 3 0 Dopey, N-terminal ANAPC4 PF12896.7 KKK21059.1 - 1.7e-68 230.2 2.4 2.4e-68 229.7 2.4 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 ANAPC4_WD40 PF12894.7 KKK21059.1 - 2e-08 34.4 0.0 2.1e-07 31.1 0.0 2.7 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain HpaP PF09483.10 KKK21059.1 - 0.0052 17.0 0.8 0.013 15.7 0.8 1.7 1 0 0 1 1 1 1 Type III secretion protein (HpaP) Tudor_3 PF18115.1 KKK21059.1 - 0.08 12.8 0.2 8.6 6.3 0.0 3.2 3 0 0 3 3 3 0 DNA repair protein Crb2 Tudor domain Gly_transf_sug PF04488.15 KKK21061.1 - 6.3e-21 74.8 0.1 1.1e-20 74.0 0.1 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 KKK21061.1 - 0.016 14.6 0.1 0.026 13.9 0.1 1.3 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein DUF4139 PF13598.6 KKK21062.1 - 2.8e-31 108.9 0.0 4.6e-31 108.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4139) DUF4140 PF13600.6 KKK21062.1 - 3.6e-21 75.4 0.5 3.6e-21 75.4 0.5 2.8 3 0 0 3 3 3 1 N-terminal domain of unknown function (DUF4140) Nucleoporin_FG PF13634.6 KKK21062.1 - 0.025 15.4 16.6 0.32 11.8 15.4 2.4 1 1 1 2 2 2 0 Nucleoporin FG repeat region End3 PF12761.7 KKK21062.1 - 0.026 14.7 2.3 0.098 12.8 0.5 2.2 2 0 0 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 CAP_N PF01213.19 KKK21062.1 - 9.6 5.6 7.0 19 4.6 7.0 1.5 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal ATP-synt_C PF00137.21 KKK21063.1 - 3.1e-09 37.1 13.4 5e-09 36.4 13.4 1.4 1 0 0 1 1 1 1 ATP synthase subunit C DUF1772 PF08592.11 KKK21064.1 - 1.9e-32 112.4 5.4 2.4e-32 112.1 5.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) BTB PF00651.31 KKK21065.1 - 2e-13 50.5 0.2 3.9e-12 46.4 0.0 2.1 2 0 0 2 2 2 1 BTB/POZ domain LETM1 PF07766.13 KKK21066.1 - 0.027 13.8 0.0 0.043 13.2 0.0 1.3 1 0 0 1 1 1 0 LETM1-like protein Arylesterase PF01731.20 KKK21067.1 - 0.00011 22.4 0.0 0.0017 18.5 0.0 2.7 3 0 0 3 3 3 1 Arylesterase WD40 PF00400.32 KKK21090.1 - 5.2e-63 207.5 13.2 1.3e-09 38.5 0.1 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKK21090.1 - 1.8e-21 76.2 0.1 0.00021 21.5 0.0 6.7 2 2 5 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain Tup_N PF08581.10 KKK21090.1 - 2.9e-09 37.1 3.8 4.2e-09 36.6 3.8 1.2 1 0 0 1 1 1 1 Tup N-terminal WD40_like PF17005.5 KKK21090.1 - 7.1e-09 35.4 0.0 0.067 12.5 0.0 4.1 3 1 2 5 5 5 3 WD40-like domain Ge1_WD40 PF16529.5 KKK21090.1 - 1.6e-06 27.3 0.1 0.35 9.8 0.0 4.8 1 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KKK21090.1 - 1e-05 24.4 0.1 0.21 10.2 0.0 3.3 2 1 1 3 3 3 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 KKK21090.1 - 1.5e-05 23.7 0.3 0.00024 19.8 0.2 2.5 1 1 1 2 2 2 2 Cytochrome D1 heme domain eIF2A PF08662.11 KKK21090.1 - 0.00026 20.9 0.0 0.039 13.8 0.0 3.0 1 1 2 3 3 3 1 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.6 KKK21090.1 - 0.015 14.6 0.1 5.6 6.2 0.0 2.9 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal Baculo_PEP_C PF04513.12 KKK21102.1 - 0.12 12.4 11.6 0.18 11.8 0.5 3.7 4 1 1 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus Abhydrolase_9_N PF15420.6 KKK21102.1 - 1.1 9.3 5.7 0.21 11.6 0.9 2.2 2 0 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus Coilin_N PF15862.5 KKK21103.1 - 0.034 14.0 0.0 0.034 14.0 0.0 2.6 3 1 0 3 3 3 0 Coilin N-terminus zf-MYND PF01753.18 KKK21103.1 - 0.074 13.2 8.5 0.21 11.7 8.5 1.8 1 0 0 1 1 1 0 MYND finger Glyco_hydro_98M PF08306.11 KKK21104.1 - 0.051 12.9 1.1 0.061 12.6 0.1 1.5 2 0 0 2 2 2 0 Glycosyl hydrolase family 98 Ald_Xan_dh_C2 PF02738.18 KKK21105.1 - 5.3e-190 632.5 2.8 7.8e-190 632.0 2.8 1.2 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.21 KKK21105.1 - 1.8e-45 154.7 0.0 3.9e-45 153.6 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Ald_Xan_dh_C PF01315.22 KKK21105.1 - 2.3e-34 118.1 0.0 4.9e-34 117.0 0.0 1.6 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain CO_deh_flav_C PF03450.17 KKK21105.1 - 1.8e-32 111.5 0.0 8e-32 109.5 0.0 2.2 2 0 0 2 2 2 1 CO dehydrogenase flavoprotein C-terminal domain Fer2_2 PF01799.20 KKK21105.1 - 1.3e-28 98.8 0.1 2.8e-28 97.8 0.1 1.6 1 0 0 1 1 1 1 [2Fe-2S] binding domain Fer2 PF00111.27 KKK21105.1 - 2.8e-08 33.6 0.1 2.8e-08 33.6 0.1 2.4 3 0 0 3 3 3 1 2Fe-2S iron-sulfur cluster binding domain DUF218 PF02698.17 KKK21105.1 - 0.07 13.1 0.0 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 DUF218 domain Reprolysin_5 PF13688.6 KKK21106.1 - 1.2e-44 152.8 15.3 1.2e-44 152.8 15.3 3.4 2 2 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.6 KKK21106.1 - 3.1e-39 134.9 7.7 3.1e-39 134.9 7.7 1.9 2 1 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 KKK21106.1 - 4.4e-38 131.0 8.2 1.3e-35 122.9 8.2 2.4 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.23 KKK21106.1 - 2.4e-17 63.5 33.2 2.4e-17 63.5 33.2 4.9 4 1 0 4 4 4 1 Disintegrin Reprolysin_3 PF13582.6 KKK21106.1 - 1.2e-06 29.0 0.1 1.2e-06 29.0 0.1 2.0 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like ADAM_CR_2 PF17771.1 KKK21106.1 - 6.6e-06 26.6 10.8 6.6e-06 26.6 10.8 5.3 2 1 2 4 4 4 1 ADAM cysteine-rich domain Pep_M12B_propep PF01562.19 KKK21106.1 - 0.004 17.4 0.9 0.008 16.4 0.1 1.9 2 0 0 2 2 2 1 Reprolysin family propeptide EF-hand_1 PF00036.32 KKK21107.1 - 3.2e-16 57.6 0.8 1.9e-05 23.9 0.1 3.5 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 KKK21107.1 - 1.2e-15 57.7 2.2 2e-09 37.7 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KKK21107.1 - 7.3e-14 50.5 2.7 1.9e-05 24.2 0.2 3.8 4 0 0 4 4 4 2 EF-hand domain EF-hand_8 PF13833.6 KKK21107.1 - 3.6e-11 42.7 0.3 4.7e-08 32.8 0.1 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 KKK21107.1 - 0.069 12.7 5.8 1.5 8.4 0.1 3.1 3 0 0 3 3 3 0 EF hand EF-hand_4 PF12763.7 KKK21107.1 - 0.13 12.2 0.0 0.35 10.8 0.0 1.6 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand MgsA_C PF12002.8 KKK21108.1 - 9.4e-59 198.1 0.2 2.4e-58 196.8 0.1 1.7 2 0 0 2 2 2 1 MgsA AAA+ ATPase C terminal AAA_assoc_2 PF16193.5 KKK21108.1 - 3e-22 78.8 0.2 8.7e-22 77.3 0.2 1.8 1 0 0 1 1 1 1 AAA C-terminal domain AAA PF00004.29 KKK21108.1 - 6.1e-15 55.8 0.0 1.4e-14 54.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KKK21108.1 - 1e-10 41.6 0.0 2.1e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 KKK21108.1 - 8.6e-06 25.3 0.1 0.061 12.7 0.0 2.3 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KKK21108.1 - 1.8e-05 24.8 0.0 0.00019 21.5 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 KKK21108.1 - 1.9e-05 24.5 0.0 0.00011 22.0 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KKK21108.1 - 0.00018 21.3 0.0 0.01 15.5 0.0 2.3 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_16 PF13191.6 KKK21108.1 - 0.00045 20.6 0.2 0.2 12.1 0.0 3.0 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 KKK21108.1 - 0.0032 17.7 0.0 0.01 16.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KKK21108.1 - 0.0041 17.5 0.2 0.019 15.3 0.2 1.8 1 1 1 2 2 2 1 AAA domain AAA_14 PF13173.6 KKK21108.1 - 0.013 15.6 0.0 0.025 14.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.6 KKK21108.1 - 0.016 15.3 0.0 0.034 14.3 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain DUF815 PF05673.13 KKK21108.1 - 0.017 14.3 0.0 0.028 13.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) TIP49 PF06068.13 KKK21108.1 - 0.017 14.3 0.0 0.047 12.9 0.0 1.5 1 1 0 1 1 1 0 TIP49 P-loop domain ResIII PF04851.15 KKK21108.1 - 0.021 14.8 0.2 0.81 9.7 0.0 2.2 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit AAA_30 PF13604.6 KKK21108.1 - 0.032 13.9 0.2 0.083 12.6 0.2 1.7 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KKK21108.1 - 0.045 14.0 0.2 0.13 12.5 0.2 1.8 2 0 0 2 2 1 0 AAA domain AAA_18 PF13238.6 KKK21108.1 - 0.046 14.3 0.0 0.087 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain SKI PF01202.22 KKK21108.1 - 0.064 13.4 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 Shikimate kinase Zeta_toxin PF06414.12 KKK21108.1 - 0.087 12.1 0.0 0.2 10.9 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_24 PF13479.6 KKK21108.1 - 0.088 12.5 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain zf-WRNIP1_ubi PF18279.1 KKK21108.1 - 0.12 13.0 0.1 0.36 11.6 0.1 1.9 1 0 0 1 1 1 0 Werner helicase-interacting protein 1 ubiquitin-binding domain RNA_helicase PF00910.22 KKK21108.1 - 0.13 12.6 0.0 0.26 11.7 0.0 1.5 1 0 0 1 1 1 0 RNA helicase CPT PF07931.12 KKK21108.1 - 0.13 12.0 0.1 0.6 9.9 0.0 1.9 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein AAA_29 PF13555.6 KKK21108.1 - 0.18 11.6 0.0 12 5.7 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain TsaE PF02367.17 KKK21108.1 - 0.19 11.7 0.0 0.43 10.6 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Aminotran_1_2 PF00155.21 KKK21109.1 - 1.9e-59 201.7 0.0 1.5e-58 198.7 0.0 2.1 1 1 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KKK21109.1 - 0.0003 19.5 0.0 0.0005 18.7 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 KKK21109.1 - 0.0057 16.0 0.0 0.0085 15.4 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 KKK21109.1 - 0.0096 15.3 0.0 0.022 14.1 0.0 1.6 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 KKK21109.1 - 0.012 14.6 0.0 0.027 13.5 0.0 1.4 2 0 0 2 2 2 0 Aminotransferase class-V IMS PF00817.20 KKK21110.1 - 1.3e-37 129.1 0.0 9e-37 126.4 0.0 2.0 2 0 0 2 2 2 1 impB/mucB/samB family IMS_C PF11799.8 KKK21110.1 - 5.6e-15 56.1 0.1 4.1e-14 53.3 0.2 2.3 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 KKK21110.1 - 0.00075 19.7 0.0 0.0019 18.4 0.0 1.7 1 0 0 1 1 1 1 IMS family HHH motif Pkinase PF00069.25 KKK21116.1 - 1.6e-20 73.6 0.0 6.1e-12 45.5 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KKK21116.1 - 1.6e-08 34.1 0.0 6.5e-05 22.3 0.0 2.8 2 1 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.14 KKK21116.1 - 0.0001 21.8 0.0 0.00018 21.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KKK21116.1 - 0.00049 19.5 0.0 0.5 9.6 0.0 3.0 3 0 0 3 3 3 1 Kinase-like APH PF01636.23 KKK21116.1 - 0.0012 18.9 0.0 0.0022 18.0 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family HATPase_c PF02518.26 KKK21117.1 - 2.3e-26 92.5 0.0 5.4e-25 88.1 0.0 2.4 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KKK21117.1 - 4.2e-24 84.9 0.0 1.1e-23 83.6 0.0 1.7 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 KKK21117.1 - 1.4e-17 63.5 0.1 3.3e-17 62.3 0.1 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS PF00989.25 KKK21117.1 - 1.9e-14 53.6 0.0 4.9e-09 36.2 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 KKK21117.1 - 1.3e-12 47.9 0.0 2.3e-10 40.6 0.0 2.5 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.10 KKK21117.1 - 2.3e-09 37.5 0.0 0.00012 22.3 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_3 PF08447.12 KKK21117.1 - 0.066 13.5 0.1 0.15 12.4 0.1 1.6 1 0 0 1 1 1 0 PAS fold Oxysterol_BP PF01237.18 KKK21123.1 - 2.6e-133 444.5 0.0 3.5e-132 440.8 0.0 2.2 2 0 0 2 2 2 1 Oxysterol-binding protein ATP12 PF07542.11 KKK21123.1 - 1.8e-47 160.6 1.4 4.3e-47 159.4 1.4 1.7 1 0 0 1 1 1 1 ATP12 chaperone protein Ank_5 PF13857.6 KKK21123.1 - 1.6e-12 47.4 0.1 4.4e-09 36.4 0.1 3.4 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KKK21123.1 - 7e-12 45.8 0.0 6.9e-08 33.0 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) PH PF00169.29 KKK21123.1 - 1e-10 42.1 0.6 2.3e-10 40.9 0.6 1.7 1 0 0 1 1 1 1 PH domain Ank PF00023.30 KKK21123.1 - 7.8e-09 35.6 0.0 0.0019 18.6 0.0 3.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 KKK21123.1 - 2.5e-08 33.5 0.0 0.0059 17.0 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 KKK21123.1 - 6.2e-08 33.0 0.0 0.00022 21.7 0.0 3.3 2 1 0 2 2 2 2 Ankyrin repeats (many copies) PH_8 PF15409.6 KKK21123.1 - 7.8e-07 29.3 0.9 2.2e-06 27.9 0.9 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 KKK21123.1 - 1.6e-05 25.3 4.3 4.4e-05 23.8 1.4 2.7 2 0 0 2 2 2 1 Pleckstrin homology domain XRN_M PF17846.1 KKK21123.1 - 0.049 12.6 1.5 0.095 11.6 1.5 1.4 1 0 0 1 1 1 0 Xrn1 helical domain LLC1 PF14945.6 KKK21123.1 - 0.17 12.5 6.8 0.26 11.9 0.6 3.0 2 0 0 2 2 2 0 Normal lung function maintenance, Low in Lung Cancer 1 protein MeaB PF03308.16 KKK21123.1 - 3.5 6.5 5.6 2.7 6.9 0.9 2.6 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB zf-Mss51 PF13824.6 KKK21124.1 - 4e-28 97.3 6.3 7.6e-28 96.4 6.3 1.5 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 zf-MYND PF01753.18 KKK21124.1 - 0.019 15.1 2.4 0.032 14.3 0.4 2.2 2 0 0 2 2 2 0 MYND finger zf-HIT PF04438.16 KKK21124.1 - 0.28 11.1 2.7 1.9 8.4 0.3 2.4 2 0 0 2 2 2 0 HIT zinc finger Glyco_tranf_2_3 PF13641.6 KKK21125.1 - 1.9e-32 113.0 0.1 2.2e-32 112.8 0.1 1.0 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 KKK21125.1 - 8.4e-09 35.1 0.0 6.6e-08 32.2 0.0 2.1 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 KKK21125.1 - 9.6e-09 35.3 0.0 1.4e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 adh_short PF00106.25 KKK21127.1 - 9.2e-23 80.7 0.0 1.2e-22 80.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KKK21127.1 - 1.5e-15 57.5 0.0 1.8e-15 57.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KKK21127.1 - 3.5e-08 33.6 0.0 4.7e-08 33.1 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KKK21127.1 - 0.0051 16.3 0.4 0.02 14.4 0.4 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KKK21127.1 - 0.061 13.2 0.1 0.087 12.7 0.1 1.3 1 0 0 1 1 1 0 NAD(P)H-binding Ank_4 PF13637.6 KKK21128.1 - 1.2e-23 83.1 0.6 1.1e-08 35.4 0.0 3.7 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KKK21128.1 - 1.1e-22 80.5 0.0 2.2e-11 44.2 0.0 2.5 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.30 KKK21128.1 - 1.5e-19 69.5 1.7 0.00046 20.5 0.0 4.9 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 KKK21128.1 - 2.2e-19 69.3 4.3 1.1e-05 25.6 0.0 3.7 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KKK21128.1 - 1e-17 62.4 0.2 0.0013 19.1 0.0 4.7 4 0 0 4 4 4 4 Ankyrin repeat bZIP_2 PF07716.15 KKK21128.1 - 2e-05 24.6 0.7 3.1e-05 24.0 0.7 1.2 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 KKK21128.1 - 4.8e-05 23.4 3.8 8.1e-05 22.6 3.8 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 KKK21128.1 - 0.11 13.1 3.9 0.18 12.3 3.9 1.3 1 0 0 1 1 1 0 bZIP Maf transcription factor DUF829 PF05705.14 KKK21129.1 - 2.6e-45 155.2 0.0 3e-31 109.2 0.0 2.0 2 0 0 2 2 2 2 Eukaryotic protein of unknown function (DUF829) NmrA PF05368.13 KKK21130.1 - 2.9e-14 53.2 0.0 7.1e-14 51.9 0.0 1.6 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KKK21130.1 - 1.2e-12 48.1 0.0 1.9e-12 47.5 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KKK21130.1 - 0.12 11.3 0.0 0.19 10.7 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Lipase_GDSL_2 PF13472.6 KKK21131.1 - 4.9e-20 72.7 0.0 9.5e-20 71.7 0.0 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KKK21131.1 - 1e-11 45.2 0.0 1.5e-11 44.7 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase DsrH PF04077.12 KKK21131.1 - 0.073 13.2 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 DsrH like protein AP_endonuc_2 PF01261.24 KKK21131.1 - 0.16 11.4 0.0 0.78 9.1 0.0 1.8 1 1 1 2 2 2 0 Xylose isomerase-like TIM barrel 4HBT_3 PF13622.6 KKK21132.1 - 2.3e-48 165.6 0.1 2.7e-48 165.4 0.1 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.22 KKK21132.1 - 0.016 15.5 0.1 0.064 13.6 0.0 2.0 2 0 0 2 2 2 0 Thioesterase superfamily FAD_binding_4 PF01565.23 KKK21133.1 - 7.1e-21 74.4 0.0 2e-20 73.0 0.0 1.8 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KKK21133.1 - 3.7e-09 36.6 0.0 7.5e-09 35.6 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like Pyr_redox_2 PF07992.14 KKK21135.1 - 2.4e-33 115.6 0.1 3.2e-33 115.2 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KKK21135.1 - 5.9e-14 52.4 0.2 2.9e-08 34.2 0.1 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KKK21135.1 - 9.8e-08 31.6 0.4 2.7e-05 23.6 0.2 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KKK21135.1 - 3.7e-06 27.0 1.6 0.24 11.4 0.0 4.0 4 0 0 4 4 4 2 FAD-NAD(P)-binding TrkA_N PF02254.18 KKK21135.1 - 2.5e-05 24.5 0.5 0.25 11.6 0.0 3.3 3 1 0 3 3 3 2 TrkA-N domain DAO PF01266.24 KKK21135.1 - 0.00012 21.8 3.5 1.5 8.4 0.0 3.6 3 1 1 4 4 4 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KKK21135.1 - 0.00032 19.9 0.4 0.03 13.4 0.0 2.4 2 0 0 2 2 2 2 Lycopene cyclase protein Thi4 PF01946.17 KKK21135.1 - 0.0016 17.8 2.1 0.18 11.0 0.2 2.5 2 0 0 2 2 2 2 Thi4 family K_oxygenase PF13434.6 KKK21135.1 - 0.0017 17.5 0.0 0.53 9.4 0.1 2.5 2 1 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) DUF1188 PF06690.11 KKK21135.1 - 0.11 12.0 0.1 3.4 7.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1188) DUF4239 PF14023.6 KKK21136.1 - 0.073 12.8 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) Laminin_II PF06009.12 KKK21137.1 - 0.0077 16.3 0.7 0.0096 15.9 0.7 1.2 1 0 0 1 1 1 1 Laminin Domain II MutS_IV PF05190.18 KKK21137.1 - 0.09 13.1 1.1 0.14 12.5 1.1 1.3 1 0 0 1 1 1 0 MutS family domain IV Phage_1_1 PF08200.11 KKK21137.1 - 0.3 11.5 2.6 0.29 11.6 0.7 2.0 2 0 0 2 2 2 0 Bacteriophage 1.1 Protein VitK2_biosynth PF02621.14 KKK21137.1 - 0.57 9.7 3.5 0.77 9.2 3.5 1.1 1 0 0 1 1 1 0 Menaquinone biosynthesis ADP_ribosyl_GH PF03747.14 KKK21138.1 - 1.2e-53 182.8 0.0 1.4e-53 182.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase EFhand_Ca_insen PF08726.10 KKK21138.1 - 0.023 14.8 0.0 0.045 13.8 0.0 1.4 1 0 0 1 1 1 0 Ca2+ insensitive EF hand DUF3725 PF12523.8 KKK21138.1 - 0.089 13.1 0.0 0.28 11.5 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3725) Rick_17kDa_Anti PF05433.15 KKK21138.1 - 0.28 11.1 4.0 3.9 7.4 0.5 2.4 2 0 0 2 2 2 0 Glycine zipper 2TM domain KxDL PF10241.9 KKK21146.1 - 1.8e-32 111.4 0.5 2.4e-32 111.1 0.5 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein DUF4407 PF14362.6 KKK21146.1 - 0.046 13.1 1.5 0.055 12.8 1.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) MFS_1 PF07690.16 KKK21147.1 - 5.7e-40 137.3 36.1 2.5e-38 131.9 33.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KKK21147.1 - 1.1e-12 47.6 11.5 1.1e-12 47.6 11.5 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 KKK21147.1 - 7.2e-08 31.3 5.5 1.1e-07 30.6 5.5 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) BCAS2 PF05700.11 KKK21148.1 - 1e-66 224.6 3.1 1.1e-66 224.4 3.1 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) CRC_subunit PF08624.10 KKK21149.1 - 3.2e-50 170.1 0.1 4.6e-50 169.6 0.1 1.2 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit GEMIN8 PF15348.6 KKK21149.1 - 0.034 14.4 0.9 0.034 14.4 0.9 1.6 2 0 0 2 2 2 0 Gemini of Cajal bodies-associated protein 8 BSP_II PF05432.11 KKK21149.1 - 0.48 10.1 16.3 0.11 12.2 5.9 2.2 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) Spore_III_AF PF09581.10 KKK21149.1 - 3.2 7.7 5.8 5.9 6.9 5.8 1.3 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) Snf7 PF03357.21 KKK21150.1 - 2.1e-35 121.9 22.3 2.1e-35 121.9 22.3 2.0 2 0 0 2 2 2 2 Snf7 DUF3138 PF11336.8 KKK21150.1 - 0.11 11.1 9.8 0.22 10.1 9.8 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3138) Exonuc_VII_L PF02601.15 KKK21150.1 - 4.7 6.7 11.2 6.2 6.3 11.2 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit EI24 PF07264.11 KKK21152.1 - 2.4e-18 67.0 13.4 3e-18 66.7 13.4 1.1 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) Fer4_14 PF13394.6 KKK21152.1 - 0.029 14.5 0.0 0.047 13.8 0.0 1.2 1 0 0 1 1 1 0 4Fe-4S single cluster domain DC_STAMP PF07782.13 KKK21152.1 - 1.5 8.6 4.6 3.6 7.4 0.1 2.2 2 0 0 2 2 2 0 DC-STAMP-like protein Zn_clus PF00172.18 KKK21153.1 - 1.6e-08 34.5 10.3 3.3e-08 33.5 10.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KKK21153.1 - 0.086 11.8 0.0 0.13 11.3 0.0 1.4 1 0 0 1 1 1 0 Fungal specific transcription factor domain Ceramidase_alk PF04734.13 KKK21154.1 - 6.3e-211 701.4 0.0 7.3e-211 701.2 0.0 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, N-terminal Ceramidse_alk_C PF17048.5 KKK21154.1 - 1.8e-54 184.1 0.1 2.8e-54 183.5 0.1 1.3 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, C-terminal Mito_carr PF00153.27 KKK21155.1 - 9.1e-54 179.4 0.3 1.3e-16 60.3 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Antimicrobial_2 PF08023.12 KKK21155.1 - 0.16 12.5 0.5 0.49 11.0 0.5 1.8 1 0 0 1 1 1 0 Frog antimicrobial peptide GTP_EFTU PF00009.27 KKK21156.1 - 2.4e-28 99.0 2.9 2.4e-28 99.0 2.9 2.5 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 KKK21156.1 - 2e-26 92.1 0.0 5.3e-26 90.8 0.0 1.7 1 0 0 1 1 1 1 Translation-initiation factor 2 IF2_N PF04760.15 KKK21156.1 - 6.5e-11 41.9 0.0 1.7e-10 40.5 0.0 1.8 1 0 0 1 1 1 1 Translation initiation factor IF-2, N-terminal region MMR_HSR1 PF01926.23 KKK21156.1 - 8.3e-09 35.5 0.4 3.1e-08 33.7 0.1 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 KKK21156.1 - 5.1e-06 26.8 1.7 0.078 13.4 0.1 3.0 2 0 0 2 2 2 2 Elongation factor Tu domain 2 Arf PF00025.21 KKK21156.1 - 0.0032 16.9 0.0 0.0059 16.1 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KKK21156.1 - 0.0081 15.6 0.0 0.0081 15.6 0.0 2.2 3 0 0 3 3 3 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 KKK21156.1 - 0.12 12.2 0.1 0.37 10.5 0.1 1.8 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.23 KKK21156.1 - 0.75 9.8 4.3 34 4.4 0.0 3.9 3 1 1 4 4 4 0 Dynamin family AAA_23 PF13476.6 KKK21156.1 - 3.3 8.2 6.7 14 6.1 0.0 3.5 4 0 0 4 4 4 0 AAA domain Zn_clus PF00172.18 KKK21158.1 - 0.0012 18.9 6.0 0.0019 18.3 6.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AT_hook PF02178.19 KKK21158.1 - 0.1 12.5 6.8 0.33 11.0 6.8 1.9 1 0 0 1 1 1 0 AT hook motif Glyco_transf_20 PF00982.21 KKK21161.1 - 2.9e-200 666.0 0.0 3.3e-200 665.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glyco_transf_5 PF08323.11 KKK21161.1 - 0.0068 16.1 0.1 0.021 14.5 0.1 1.7 1 1 0 1 1 1 1 Starch synthase catalytic domain BLACT_WH PF17778.1 KKK21162.1 - 8.8e-18 64.0 0.3 2.5e-17 62.6 0.0 1.9 2 0 0 2 2 2 1 Beta-lactamase associated winged helix domain Lactamase_B PF00753.27 KKK21162.1 - 1.3e-15 57.9 4.8 7.6e-14 52.2 4.8 2.2 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KKK21162.1 - 2.5e-07 30.4 0.6 4.9e-07 29.5 0.6 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Cnd1 PF12717.7 KKK21163.1 - 7.9e-05 22.8 0.3 0.78 9.8 0.0 3.3 2 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KKK21163.1 - 0.00057 19.9 0.1 1.8 9.0 0.2 4.5 4 0 0 4 4 4 1 HEAT repeat CLASP_N PF12348.8 KKK21163.1 - 0.00097 18.8 0.3 0.084 12.4 0.3 3.1 2 1 1 3 3 3 1 CLASP N terminal TAN PF11640.8 KKK21163.1 - 0.0011 19.1 0.3 0.0084 16.3 0.3 2.4 1 1 0 1 1 1 1 Telomere-length maintenance and DNA damage repair Adaptin_N PF01602.20 KKK21163.1 - 0.0081 14.8 1.2 0.074 11.6 1.2 2.3 1 1 0 1 1 1 1 Adaptin N terminal region Syntaxin PF00804.25 KKK21163.1 - 0.016 14.9 3.9 0.053 13.2 3.9 1.8 1 0 0 1 1 1 0 Syntaxin MMS19_N PF14500.6 KKK21163.1 - 0.016 14.8 0.4 0.9 9.1 0.3 3.0 2 1 1 3 3 3 0 Dos2-interacting transcription regulator of RNA-Pol-II Golgin_A5 PF09787.9 KKK21163.1 - 0.02 14.4 8.5 0.052 13.0 8.5 1.6 1 0 0 1 1 1 0 Golgin subfamily A member 5 PhoU_div PF01865.16 KKK21163.1 - 0.066 12.5 0.5 0.24 10.7 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function DUF47 DUF2353 PF09789.9 KKK21163.1 - 0.44 9.9 9.0 0.62 9.4 7.8 1.7 2 0 0 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) Spc7 PF08317.11 KKK21163.1 - 1.2 8.0 9.9 0.11 11.4 4.6 1.9 2 0 0 2 2 2 0 Spc7 kinetochore protein Atg14 PF10186.9 KKK21163.1 - 1.8 7.5 7.6 4.1 6.4 7.6 1.5 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 ADIP PF11559.8 KKK21163.1 - 2.7 8.1 14.2 8.8 6.4 14.2 1.8 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Mod_r PF07200.13 KKK21163.1 - 2.7 8.1 11.0 0.29 11.2 5.9 2.0 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein UPF0242 PF06785.11 KKK21163.1 - 4 7.5 7.7 12 5.9 7.7 1.8 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF724 PF05266.14 KKK21163.1 - 5.5 6.8 8.3 15 5.4 8.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Ribosomal_S17 PF00366.20 KKK21164.1 - 1.8e-12 47.2 0.4 2.8e-12 46.5 0.4 1.3 1 0 0 1 1 1 1 Ribosomal protein S17 Nucleo_P87 PF07267.11 KKK21164.1 - 0.097 11.5 2.8 0.11 11.3 2.8 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 BUD22 PF09073.10 KKK21164.1 - 0.56 9.5 6.1 9.7 5.4 3.4 2.0 2 0 0 2 2 2 0 BUD22 Mito_carr PF00153.27 KKK21165.1 - 5.7e-48 160.8 1.0 8.7e-21 73.7 0.0 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein Vac14_Fig4_bd PF11916.8 KKK21166.1 - 1.9e-80 268.7 8.6 1.9e-80 268.7 8.6 1.7 2 0 0 2 2 2 1 Vacuolar protein 14 C-terminal Fig4p binding Rad54_N PF08658.10 KKK21166.1 - 1.2e-58 198.2 1.4 1.3e-57 194.9 1.0 2.5 2 0 0 2 2 2 1 Rad54 N terminal SNF2_N PF00176.23 KKK21166.1 - 3.4e-56 190.5 0.0 5.8e-56 189.7 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Vac14_Fab1_bd PF12755.7 KKK21166.1 - 1.9e-42 143.8 0.0 1.8e-40 137.5 0.0 3.7 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region Helicase_C PF00271.31 KKK21166.1 - 4.7e-15 55.9 0.0 1.6e-14 54.2 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HEAT_EZ PF13513.6 KKK21166.1 - 3.8e-08 33.7 0.9 0.01 16.3 0.0 4.2 3 1 1 4 4 4 2 HEAT-like repeat ResIII PF04851.15 KKK21166.1 - 3.4e-06 27.2 0.0 1.7e-05 24.9 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HEAT PF02985.22 KKK21166.1 - 6.9e-06 25.9 1.2 0.0022 18.1 0.0 4.4 4 0 0 4 4 4 1 HEAT repeat Cnd1 PF12717.7 KKK21166.1 - 0.00011 22.3 1.8 0.075 13.1 0.7 2.8 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KKK21166.1 - 0.0053 17.1 0.1 4.7 7.7 0.0 4.0 3 1 0 3 3 3 1 HEAT repeats HDA2-3 PF11496.8 KKK21166.1 - 0.0071 15.5 0.0 0.027 13.6 0.0 2.0 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 IBN_N PF03810.19 KKK21166.1 - 0.045 13.7 0.1 0.34 10.8 0.0 2.6 2 1 0 2 2 2 0 Importin-beta N-terminal domain Aconitase PF00330.20 KKK21167.1 - 1.5e-150 502.2 0.0 2.1e-150 501.8 0.0 1.2 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KKK21167.1 - 3.2e-43 147.2 0.0 5.7e-43 146.4 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain zf-C2H2_jaz PF12171.8 KKK21168.1 - 1.1e-09 38.3 4.0 1.7e-09 37.7 4.0 1.3 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KKK21168.1 - 0.04 14.3 1.7 0.077 13.4 1.7 1.5 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 KKK21168.1 - 0.11 12.8 0.4 0.16 12.3 0.4 1.3 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 KKK21168.1 - 0.12 13.2 0.8 0.27 12.2 0.8 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger zf-SCNM1 PF15803.5 KKK21168.1 - 0.14 11.8 0.1 0.26 10.9 0.1 1.5 1 0 0 1 1 1 0 Zinc-finger of sodium channel modifier 1 ATP-synt_10 PF05176.14 KKK21169.1 - 5.5e-85 284.7 0.0 7.7e-85 284.2 0.0 1.1 1 0 0 1 1 1 1 ATP10 protein Stn1 PF10451.9 KKK21181.1 - 2.9e-08 33.0 0.0 5.4e-06 25.5 0.0 2.1 2 0 0 2 2 2 2 Telomere regulation protein Stn1 NAPRTase_C PF17956.1 KKK21181.1 - 0.12 12.9 0.1 0.27 11.7 0.0 1.5 2 0 0 2 2 2 0 Nicotinate phosphoribosyltransferase C-terminal domain Herpes_UL56 PF04534.12 KKK21181.1 - 9.4 5.7 8.0 16 4.9 8.0 1.3 1 0 0 1 1 1 0 Herpesvirus UL56 protein DnaJ PF00226.31 KKK21182.1 - 9.3e-24 83.3 1.8 2.4e-23 82.0 1.8 1.8 1 0 0 1 1 1 1 DnaJ domain Stc1 PF12898.7 KKK21184.1 - 5.9e-18 65.2 3.8 1e-17 64.4 3.8 1.4 1 0 0 1 1 1 1 Stc1 domain FAM60A PF15396.6 KKK21184.1 - 0.076 13.0 1.9 0.18 11.8 1.9 1.5 1 0 0 1 1 1 0 Protein Family FAM60A zf-RING_10 PF16685.5 KKK21184.1 - 0.95 9.7 4.9 2.1 8.5 4.9 1.5 1 1 0 1 1 1 0 zinc RING finger of MSL2 Amidase PF01425.21 KKK21185.1 - 7.9e-64 216.3 0.0 1e-52 179.7 0.0 2.6 1 1 1 2 2 2 2 Amidase ArAE_2_N PF10337.9 KKK21203.1 - 1.7e-56 192.3 6.5 1.7e-56 192.3 6.5 4.9 3 1 0 3 3 3 1 Putative ER transporter, 6TM, N-terminal FUSC_2 PF13515.6 KKK21203.1 - 1.8e-19 70.1 10.8 1.8e-19 70.1 10.8 3.4 3 2 1 4 4 4 1 Fusaric acid resistance protein-like MFS_1 PF07690.16 KKK21203.1 - 1.5e-15 57.0 14.1 1.5e-15 57.0 14.1 3.6 3 1 0 3 3 3 1 Major Facilitator Superfamily ArAE_2 PF10334.9 KKK21203.1 - 3.2e-14 53.3 0.0 2.7e-13 50.3 0.0 2.2 2 0 0 2 2 2 1 Aromatic acid exporter family member 2 Sugar_tr PF00083.24 KKK21203.1 - 2.8e-06 26.5 6.1 2.8e-06 26.5 6.1 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter ArAE_1 PF06081.11 KKK21203.1 - 0.0026 17.9 7.0 0.0026 17.9 7.0 3.9 4 1 1 5 5 5 1 Aromatic acid exporter family member 1 FUSC PF04632.12 KKK21203.1 - 0.076 11.5 5.2 0.14 10.7 0.6 3.3 4 0 0 4 4 4 0 Fusaric acid resistance protein family TRI12 PF06609.13 KKK21204.1 - 0.00099 17.6 3.4 0.0012 17.3 3.4 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) 7tm_7 PF08395.12 KKK21204.1 - 0.08 12.1 3.0 0.16 11.2 2.7 1.5 2 0 0 2 2 2 0 7tm Chemosensory receptor Fungal_trans PF04082.18 KKK21220.1 - 7e-17 61.3 0.0 1.3e-16 60.5 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK21220.1 - 0.00092 19.3 5.9 0.0017 18.4 5.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RNA_pol_Rpb4 PF03874.16 KKK21221.1 - 8.9e-26 90.6 2.7 1.2e-25 90.2 2.7 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb4 Cut8 PF08559.10 KKK21221.1 - 0.003 17.2 0.3 0.0036 16.9 0.3 1.2 1 0 0 1 1 1 1 Cut8, nuclear proteasome tether protein Met_10 PF02475.16 KKK21222.1 - 1.1e-61 208.1 0.0 1.6e-61 207.5 0.0 1.3 1 1 0 1 1 1 1 Met-10+ like-protein LAT PF15234.6 KKK21222.1 - 0.2 11.4 0.0 0.3 10.8 0.0 1.2 1 0 0 1 1 1 0 Linker for activation of T-cells TRM PF02005.16 KKK21222.1 - 0.22 10.7 0.0 0.32 10.1 0.0 1.2 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase Proteasome PF00227.26 KKK21223.1 - 2e-49 167.7 0.1 3.1e-49 167.0 0.1 1.3 1 0 0 1 1 1 1 Proteasome subunit DUF2373 PF10180.9 KKK21223.1 - 2.2e-19 69.0 0.1 4.3e-19 68.1 0.1 1.5 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) RVT_2 PF07727.14 KKK21224.1 - 2.7e-29 102.5 0.8 5.8e-28 98.2 0.8 2.2 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SIS PF01380.22 KKK21225.1 - 5e-59 197.8 0.0 3e-32 111.2 0.1 2.3 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 KKK21225.1 - 6.3e-18 65.3 0.0 1.2e-17 64.4 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 KKK21225.1 - 1.6e-10 41.0 0.0 3.1e-10 40.0 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 KKK21225.1 - 5.9e-05 22.1 0.0 9.4e-05 21.4 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II GATase_2 PF00310.21 KKK21225.1 - 0.059 12.1 0.0 0.26 10.0 0.0 1.8 2 0 0 2 2 2 0 Glutamine amidotransferases class-II Holin_BhlA PF10960.8 KKK21225.1 - 0.1 12.6 0.0 0.32 11.0 0.0 1.8 1 0 0 1 1 1 0 BhlA holin family DMRL_synthase PF00885.19 KKK21226.1 - 1.3e-56 190.3 0.0 1.6e-56 190.0 0.0 1.1 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase POTRA_TamA_1 PF17243.2 KKK21227.1 - 0.072 13.2 1.2 0.16 12.1 1.2 1.5 1 0 0 1 1 1 0 POTRA domain TamA domain 1 Rad4 PF03835.15 KKK21228.1 - 1.9e-38 131.4 0.3 5.1e-38 130.0 0.3 1.8 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_3 PF10405.9 KKK21228.1 - 6.3e-29 100.2 0.1 1.1e-28 99.4 0.1 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.9 KKK21228.1 - 1.1e-14 54.0 0.0 2.5e-14 52.8 0.0 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.9 KKK21228.1 - 3.7e-13 50.2 1.5 3.7e-13 50.2 1.5 3.8 4 0 0 4 4 4 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.19 KKK21228.1 - 0.0061 17.0 0.0 0.35 11.3 0.0 2.7 2 0 0 2 2 2 1 Transglutaminase-like superfamily CoA_binding_2 PF13380.6 KKK21229.1 - 2.1e-27 95.9 0.0 2.6e-27 95.6 0.0 1.1 1 0 0 1 1 1 1 CoA binding domain HD_3 PF13023.6 KKK21230.1 - 1.4e-47 161.7 0.0 1.9e-47 161.3 0.0 1.1 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 KKK21230.1 - 1e-10 41.7 0.1 1.3e-10 41.3 0.1 1.2 1 0 0 1 1 1 1 HD containing hydrolase-like enzyme Il2rg PF15874.5 KKK21230.1 - 0.1 12.9 0.3 0.19 12.0 0.0 1.6 2 0 0 2 2 2 0 Putative Interleukin 2 receptor, gamma chain HIT PF01230.23 KKK21231.1 - 4.5e-18 65.8 0.0 6.6e-18 65.3 0.0 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 KKK21231.1 - 0.00047 20.6 0.0 0.00069 20.1 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DUF1375 PF07119.12 KKK21231.1 - 0.15 12.5 0.0 0.26 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1375) GalP_UDP_tr_C PF02744.17 KKK21231.1 - 0.21 11.3 0.0 0.25 11.1 0.0 1.3 1 1 0 1 1 1 0 Galactose-1-phosphate uridyl transferase, C-terminal domain HAUS6_N PF14661.6 KKK21232.1 - 2.1e-42 145.3 0.3 3.8e-42 144.4 0.3 1.4 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 6 N-terminus AAA_6 PF12774.7 KKK21233.1 - 3.1e-125 417.5 0.0 1.5e-124 415.2 0.0 2.3 2 0 0 2 2 1 1 Hydrolytic ATP binding site of dynein motor region DHC_N1 PF08385.12 KKK21233.1 - 6.4e-125 417.9 11.5 6.4e-125 417.9 11.5 3.8 4 1 0 5 5 5 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.13 KKK21233.1 - 1.8e-115 386.3 7.5 1.8e-115 386.3 7.5 4.0 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 KKK21233.1 - 1.7e-67 227.5 0.0 1.2e-66 224.7 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_7 PF12775.7 KKK21233.1 - 3.7e-42 143.9 0.0 2.8e-36 124.7 0.0 4.7 4 0 0 4 4 4 2 P-loop containing dynein motor region AAA_5 PF07728.14 KKK21233.1 - 3.7e-32 111.2 0.0 5.1e-11 42.7 0.0 5.9 4 2 0 4 4 4 4 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 KKK21233.1 - 5.2e-20 71.8 0.1 2.1e-19 69.9 0.1 2.2 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA PF00004.29 KKK21233.1 - 5.6e-16 59.2 0.0 8e-05 23.1 0.0 5.5 6 0 0 6 6 4 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KKK21233.1 - 8.7e-15 55.2 2.1 0.0055 17.0 0.0 6.9 5 1 0 5 5 5 3 AAA domain AAA_18 PF13238.6 KKK21233.1 - 1.6e-11 44.9 0.3 0.071 13.7 0.0 5.6 5 0 0 5 5 4 3 AAA domain AAA_16 PF13191.6 KKK21233.1 - 2.6e-10 40.9 3.2 0.86 10.0 0.0 7.9 7 1 0 7 7 6 2 AAA ATPase domain AAA_33 PF13671.6 KKK21233.1 - 7.2e-10 39.2 1.9 0.27 11.4 0.0 5.5 5 0 0 5 5 4 3 AAA domain ABC_tran PF00005.27 KKK21233.1 - 1e-06 29.3 0.3 0.39 11.2 0.1 5.4 4 0 0 4 4 3 2 ABC transporter T2SSE PF00437.20 KKK21233.1 - 1e-06 28.1 0.0 0.0054 15.8 0.0 3.7 3 0 0 3 3 3 1 Type II/IV secretion system protein RsgA_GTPase PF03193.16 KKK21233.1 - 1.4e-05 25.1 0.0 4.2 7.2 0.0 4.6 4 0 0 4 4 4 1 RsgA GTPase AAA_29 PF13555.6 KKK21233.1 - 2.3e-05 24.0 0.1 1.7 8.5 0.0 3.7 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_14 PF13173.6 KKK21233.1 - 4.4e-05 23.5 0.0 1.7 8.7 0.0 4.4 4 0 0 4 4 3 2 AAA domain AAA_30 PF13604.6 KKK21233.1 - 0.00012 21.9 0.7 17 5.1 0.0 5.0 5 0 0 5 5 4 0 AAA domain FtsK_SpoIIIE PF01580.18 KKK21233.1 - 0.00013 21.4 0.0 1.2 8.4 0.0 4.0 3 0 0 3 3 3 1 FtsK/SpoIIIE family Mg_chelatase PF01078.21 KKK21233.1 - 0.0004 19.8 4.2 0.42 9.9 0.0 3.8 4 0 0 4 4 3 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 KKK21233.1 - 0.00046 20.0 0.2 16 5.1 0.0 4.8 4 0 0 4 4 4 0 AAA domain AAA_25 PF13481.6 KKK21233.1 - 0.00053 19.6 0.0 0.35 10.4 0.0 3.8 3 0 0 3 3 2 1 AAA domain AAA_lid_1 PF17857.1 KKK21233.1 - 0.00064 19.9 0.0 0.0036 17.5 0.0 2.4 1 0 0 1 1 1 1 AAA+ lid domain AAA_19 PF13245.6 KKK21233.1 - 0.00071 19.9 3.6 0.16 12.3 0.0 4.7 5 0 0 5 5 5 1 AAA domain RNA_helicase PF00910.22 KKK21233.1 - 0.0013 19.1 0.2 14 6.1 0.1 5.1 5 0 0 5 5 5 0 RNA helicase IstB_IS21 PF01695.17 KKK21233.1 - 0.0019 17.9 0.4 0.39 10.4 0.0 4.1 4 0 0 4 4 4 1 IstB-like ATP binding protein AAA_21 PF13304.6 KKK21233.1 - 0.0028 17.5 0.5 7 6.4 0.0 3.8 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system Rad17 PF03215.15 KKK21233.1 - 0.0028 17.6 0.2 4.1 7.3 0.0 4.2 5 0 0 5 5 4 1 Rad17 P-loop domain Zeta_toxin PF06414.12 KKK21233.1 - 0.015 14.6 0.1 20 4.4 0.0 3.7 3 0 0 3 3 3 0 Zeta toxin MT PF12777.7 KKK21233.1 - 0.066 12.2 9.3 0.13 11.2 9.3 1.5 1 0 0 1 1 1 0 Microtubule-binding stalk of dynein motor NTPase_1 PF03266.15 KKK21233.1 - 0.079 12.9 0.3 24 4.8 0.0 3.7 4 0 0 4 4 3 0 NTPase RuvB_N PF05496.12 KKK21233.1 - 0.084 12.6 0.0 4 7.2 0.0 3.0 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain PduV-EutP PF10662.9 KKK21233.1 - 0.18 11.5 1.5 8.3 6.1 0.1 3.6 4 0 0 4 4 3 0 Ethanolamine utilisation - propanediol utilisation AAA_17 PF13207.6 KKK21233.1 - 1 9.7 6.8 1.1e+02 3.2 0.0 4.9 4 0 0 4 4 4 0 AAA domain AAA_11 PF13086.6 KKK21233.1 - 1.3 8.7 0.0 1.3 8.7 0.0 4.1 4 0 0 4 4 3 0 AAA domain NACHT PF05729.12 KKK21233.1 - 2.9 7.8 10.0 23 4.8 0.0 5.4 7 0 0 7 7 4 0 NACHT domain DUF87 PF01935.17 KKK21233.1 - 3.4 7.7 6.7 34 4.4 0.1 4.3 3 0 0 3 3 3 0 Helicase HerA, central domain AAA_9 PF12781.7 KKK21234.1 - 1.2e-74 250.2 0.4 1.2e-74 250.2 0.4 2.3 3 0 0 3 3 3 1 ATP-binding dynein motor region Dynein_heavy PF03028.15 KKK21234.1 - 5.8e-31 107.0 0.0 2.9e-27 95.1 0.0 3.0 3 0 0 3 3 3 2 Dynein heavy chain region D6 P-loop domain AAA_lid_11 PF18198.1 KKK21234.1 - 8.8e-31 106.9 0.0 2e-30 105.7 0.0 1.7 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain MT PF12777.7 KKK21234.1 - 3.4e-25 88.8 0.3 6.2e-25 88.0 0.3 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Taxilin PF09728.9 KKK21234.1 - 2.6e-05 23.5 0.3 2.6e-05 23.5 0.3 2.1 2 0 0 2 2 2 1 Myosin-like coiled-coil protein DUF3867 PF12983.7 KKK21234.1 - 0.00027 21.0 0.5 0.00027 21.0 0.5 1.8 2 0 0 2 2 1 1 Protein of unknown function (DUF3867) BRE1 PF08647.11 KKK21234.1 - 0.0014 18.7 1.9 0.0014 18.7 1.9 2.3 2 0 0 2 2 1 1 BRE1 E3 ubiquitin ligase DUF812 PF05667.11 KKK21234.1 - 0.0018 17.3 1.6 0.0018 17.3 1.6 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF812) APG6_N PF17675.1 KKK21234.1 - 0.014 15.9 4.1 0.014 15.9 4.1 2.6 2 0 0 2 2 2 0 Apg6 coiled-coil region CLZ PF16526.5 KKK21234.1 - 0.037 14.4 0.7 0.037 14.4 0.7 3.6 5 0 0 5 5 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Jnk-SapK_ap_N PF09744.9 KKK21234.1 - 0.045 14.0 9.5 0.039 14.2 1.9 2.7 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 FapA PF03961.13 KKK21234.1 - 0.055 12.1 5.9 1.5 7.4 0.9 2.1 2 0 0 2 2 2 0 Flagellar Assembly Protein A 3-alpha PF03475.14 KKK21234.1 - 0.068 13.1 0.5 0.23 11.3 0.5 2.0 1 0 0 1 1 1 0 3-alpha domain G-gamma PF00631.22 KKK21234.1 - 0.093 12.7 0.0 0.55 10.3 0.0 2.4 1 0 0 1 1 1 0 GGL domain zf-C4H2 PF10146.9 KKK21234.1 - 0.1 12.9 1.3 0.31 11.3 0.1 2.1 2 0 0 2 2 2 0 Zinc finger-containing protein Pil1 PF13805.6 KKK21234.1 - 0.2 11.1 5.9 0.034 13.6 1.7 1.8 2 0 0 2 2 2 0 Eisosome component PIL1 DUF948 PF06103.11 KKK21234.1 - 0.34 11.2 5.7 6.6 7.1 0.4 3.9 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Fez1 PF06818.15 KKK21234.1 - 0.38 11.2 8.3 0.39 11.2 1.0 2.7 2 0 0 2 2 2 0 Fez1 Tup_N PF08581.10 KKK21234.1 - 0.41 11.0 5.8 0.67 10.3 1.5 2.9 2 0 0 2 2 2 0 Tup N-terminal Seryl_tRNA_N PF02403.22 KKK21234.1 - 0.44 10.8 7.3 0.48 10.7 1.3 2.8 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain ZapB PF06005.12 KKK21234.1 - 0.5 10.9 12.6 0.49 10.9 3.6 4.1 3 1 0 3 3 2 0 Cell division protein ZapB DUF724 PF05266.14 KKK21234.1 - 0.79 9.5 5.6 0.21 11.4 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF724) DUF3450 PF11932.8 KKK21234.1 - 0.82 8.9 10.3 0.018 14.3 2.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) FlaC_arch PF05377.11 KKK21234.1 - 0.83 10.1 3.5 3.9 7.9 0.1 3.0 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) TPR_MLP1_2 PF07926.12 KKK21234.1 - 1.2 9.2 13.7 0.21 11.7 4.4 3.2 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein GAS PF13851.6 KKK21234.1 - 1.8 7.9 10.9 1.5 8.1 1.2 2.5 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Uso1_p115_C PF04871.13 KKK21234.1 - 2.5 8.5 7.5 0.62 10.4 2.1 2.5 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region STAT_alpha PF01017.20 KKK21234.1 - 2.8 7.8 9.0 3 7.7 0.8 2.8 3 0 0 3 3 2 0 STAT protein, all-alpha domain CENP-F_leu_zip PF10473.9 KKK21234.1 - 2.8 7.9 11.0 1.4 8.9 2.3 2.5 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1664 PF07889.12 KKK21234.1 - 7.3 6.7 6.2 5 7.2 0.3 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Spc24 PF08286.11 KKK21234.1 - 9.2 6.6 8.5 1.7 9.0 1.9 2.6 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Ribonuclease_3 PF00636.26 KKK21235.1 - 6.2e-42 142.5 0.0 8.5e-20 71.3 0.0 3.7 3 0 0 3 3 3 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 KKK21235.1 - 1e-23 83.9 0.0 1e-11 45.1 0.0 3.9 2 2 0 2 2 2 2 Ribonuclease-III-like Dicer_dimer PF03368.14 KKK21235.1 - 2.8e-21 75.5 0.0 2.4e-20 72.5 0.0 2.6 2 0 0 2 2 2 1 Dicer dimerisation domain Helicase_C PF00271.31 KKK21235.1 - 4.2e-17 62.5 0.1 1.3e-16 60.9 0.1 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KKK21235.1 - 1.2e-13 51.4 0.2 4e-13 49.7 0.1 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KKK21235.1 - 3.2e-09 36.8 0.0 2.2e-08 34.0 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase dsrm PF00035.26 KKK21235.1 - 0.0002 22.0 0.0 0.59 10.9 0.0 2.7 2 0 0 2 2 2 2 Double-stranded RNA binding motif Lon_C PF05362.13 KKK21236.1 - 3.8e-69 232.3 0.4 2.6e-68 229.6 0.2 2.2 2 0 0 2 2 2 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 KKK21236.1 - 2.1e-29 102.9 0.0 4.2e-29 101.9 0.0 1.5 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 KKK21236.1 - 2.8e-23 82.8 0.0 1.6e-22 80.4 0.0 2.4 3 0 0 3 3 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KKK21236.1 - 9.2e-08 32.2 0.0 3.1e-07 30.5 0.0 2.0 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.6 KKK21236.1 - 2.2e-07 30.7 0.1 1.2e-06 28.4 0.0 2.1 2 0 0 2 2 2 1 Subunit ChlI of Mg-chelatase AAA_16 PF13191.6 KKK21236.1 - 9.3e-07 29.4 0.5 6.6e-06 26.6 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_3 PF07726.11 KKK21236.1 - 0.00014 21.7 0.0 0.00042 20.2 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KKK21236.1 - 0.00028 20.7 0.1 0.0012 18.6 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 KKK21236.1 - 0.001 19.2 0.0 0.0038 17.4 0.0 2.1 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 KKK21236.1 - 0.0016 18.7 0.2 0.026 14.8 0.0 3.0 2 1 0 2 2 1 1 AAA domain TIP49 PF06068.13 KKK21236.1 - 0.0019 17.5 0.0 0.0038 16.5 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 KKK21236.1 - 0.0041 17.3 0.0 0.016 15.3 0.0 2.1 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KKK21236.1 - 0.0073 16.1 0.0 0.021 14.6 0.0 1.8 1 0 0 1 1 1 1 IstB-like ATP binding protein Zeta_toxin PF06414.12 KKK21236.1 - 0.022 14.1 0.1 0.13 11.5 0.0 2.1 2 0 0 2 2 2 0 Zeta toxin AAA_18 PF13238.6 KKK21236.1 - 0.025 15.1 0.0 0.082 13.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KKK21236.1 - 0.041 13.8 0.1 0.2 11.6 0.0 2.2 2 0 0 2 2 1 0 NACHT domain AAA_11 PF13086.6 KKK21236.1 - 0.041 13.7 2.5 0.069 12.9 0.0 2.1 1 1 1 2 2 2 0 AAA domain AAA_25 PF13481.6 KKK21236.1 - 0.042 13.4 0.0 0.14 11.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 KKK21236.1 - 0.044 13.2 0.1 0.12 11.7 0.1 1.7 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI TsaE PF02367.17 KKK21236.1 - 0.056 13.5 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Rad17 PF03215.15 KKK21236.1 - 0.079 12.9 0.1 0.24 11.3 0.0 1.8 2 0 0 2 2 2 0 Rad17 P-loop domain RNA_helicase PF00910.22 KKK21236.1 - 0.09 13.2 0.0 0.24 11.8 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_30 PF13604.6 KKK21236.1 - 0.11 12.2 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 KKK21236.1 - 0.12 11.8 0.0 0.28 10.6 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_14 PF13173.6 KKK21236.1 - 0.17 12.0 0.0 0.4 10.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KKK21236.1 - 0.18 11.3 0.0 0.36 10.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_23 PF13476.6 KKK21236.1 - 0.23 11.9 0.0 0.23 11.9 0.0 3.0 1 1 0 2 2 1 0 AAA domain Rubis-subs-bind PF09273.11 KKK21236.1 - 0.28 11.9 2.0 6.3 7.5 0.1 2.9 2 1 0 2 2 2 0 Rubisco LSMT substrate-binding Porphobil_deam PF01379.20 KKK21237.1 - 1.9e-71 239.8 0.0 2.4e-71 239.5 0.0 1.1 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 KKK21237.1 - 1.3e-18 67.1 0.0 2.4e-18 66.2 0.0 1.4 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain Svf1_C PF17187.4 KKK21239.1 - 2.5e-60 203.1 0.0 3.3e-60 202.7 0.0 1.2 1 0 0 1 1 1 1 Svf1-like C-terminal lipocalin-like domain Svf1 PF08622.10 KKK21239.1 - 1.5e-43 148.7 0.0 2.3e-43 148.1 0.0 1.3 1 0 0 1 1 1 1 Svf1-like N-terminal lipocalin domain TAP42 PF04177.12 KKK21240.1 - 1.6e-100 336.4 10.9 1.8e-100 336.2 10.9 1.0 1 0 0 1 1 1 1 TAP42-like family RPN1_RPN2_N PF17781.1 KKK21241.1 - 5e-117 390.7 1.9 7.6e-117 390.1 1.9 1.3 1 0 0 1 1 1 1 RPN1/RPN2 N-terminal domain RIO1 PF01163.22 KKK21241.1 - 9.3e-40 136.2 0.6 6.1e-28 97.7 0.0 2.5 2 0 0 2 2 2 2 RIO1 family Rio2_N PF09202.11 KKK21241.1 - 4.4e-32 110.1 0.0 1.4e-31 108.5 0.0 1.9 1 0 0 1 1 1 1 Rio2, N-terminal RPN1_C PF18051.1 KKK21241.1 - 2.1e-26 91.7 0.0 4.7e-26 90.6 0.0 1.6 1 0 0 1 1 1 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal PC_rep PF01851.22 KKK21241.1 - 3.4e-15 55.6 13.0 0.00012 22.3 0.1 7.4 7 0 0 7 7 7 3 Proteasome/cyclosome repeat Kdo PF06293.14 KKK21241.1 - 5.5e-06 25.9 0.0 0.00013 21.4 0.0 2.3 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KKK21241.1 - 2.7e-05 24.2 0.0 0.1 12.5 0.0 2.7 1 1 1 2 2 2 2 Phosphotransferase enzyme family HEAT_2 PF13646.6 KKK21241.1 - 0.013 15.9 0.3 7.1 7.1 0.0 3.6 3 0 0 3 3 3 0 HEAT repeats Ribosomal_L23 PF00276.20 KKK21242.1 - 7.6e-11 42.2 0.0 1.2e-10 41.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L23 Mlh1_C PF16413.5 KKK21243.1 - 9.5e-102 340.0 0.0 6.8e-101 337.2 0.0 2.0 2 0 0 2 2 2 1 DNA mismatch repair protein Mlh1 C-terminus DNA_mis_repair PF01119.19 KKK21243.1 - 1e-31 109.1 0.2 1.8e-31 108.3 0.2 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 KKK21243.1 - 5.8e-13 48.9 0.0 2e-12 47.1 0.0 1.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 KKK21243.1 - 3.2e-08 34.1 0.0 3.9e-07 30.6 0.0 2.6 3 0 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Torus PF16131.5 KKK21246.1 - 2.1e-28 99.2 0.1 4.1e-28 98.2 0.0 1.5 2 0 0 2 2 2 1 Torus domain P-II PF00543.22 KKK21246.1 - 0.05 14.2 0.0 0.068 13.8 0.0 1.2 1 0 0 1 1 1 0 Nitrogen regulatory protein P-II MMR_HSR1_Xtn PF16897.5 KKK21247.1 - 4e-35 120.0 1.1 1.3e-34 118.4 0.4 2.0 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 KKK21247.1 - 5.6e-21 74.4 0.1 9.8e-21 73.6 0.1 1.4 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.23 KKK21247.1 - 1.7e-20 73.2 0.1 5.6e-20 71.5 0.0 1.9 1 1 1 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KKK21247.1 - 1.1e-11 44.6 0.0 1.7e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 KKK21247.1 - 0.00013 22.1 0.2 0.086 12.9 0.0 2.5 1 1 1 2 2 2 2 Dynamin family AIG1 PF04548.16 KKK21247.1 - 0.027 13.8 0.0 0.044 13.1 0.0 1.3 1 0 0 1 1 1 0 AIG1 family Roc PF08477.13 KKK21247.1 - 0.035 14.3 0.2 2 8.7 0.0 2.4 2 1 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Rhabdo_ncap PF00945.18 KKK21247.1 - 0.047 12.6 0.1 0.064 12.1 0.1 1.1 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein MCM PF00493.23 KKK21247.1 - 0.047 12.8 0.1 0.12 11.5 0.0 1.6 2 0 0 2 2 2 0 MCM P-loop domain MeaB PF03308.16 KKK21247.1 - 0.055 12.4 0.1 0.11 11.5 0.1 1.5 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB GATase PF00117.28 KKK21248.1 - 1.2e-46 158.9 0.0 1.7e-46 158.4 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_sm_chain PF00988.22 KKK21248.1 - 4.8e-46 155.7 0.0 9.8e-46 154.7 0.0 1.5 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase small chain, CPSase domain Peptidase_C26 PF07722.13 KKK21248.1 - 2.1e-05 24.4 0.1 0.00047 20.0 0.1 2.4 1 1 0 1 1 1 1 Peptidase C26 DJ-1_PfpI PF01965.24 KKK21248.1 - 0.023 14.5 0.0 0.04 13.7 0.0 1.4 1 0 0 1 1 1 0 DJ-1/PfpI family Zn_clus PF00172.18 KKK21249.1 - 7.1e-09 35.6 9.6 1.2e-08 34.9 9.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KKK21249.1 - 2.7e-05 23.3 0.0 4.2e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain ABC2_membrane PF01061.24 KKK21251.1 - 3e-43 147.7 19.8 3e-43 147.7 19.8 1.7 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 KKK21251.1 - 6.4e-38 130.4 0.0 3.3e-18 66.5 0.0 2.6 3 0 0 3 3 2 2 ABC transporter PDR_CDR PF06422.12 KKK21251.1 - 3.2e-33 113.5 1.5 8.1e-33 112.2 0.0 2.3 2 0 0 2 2 2 1 CDR ABC transporter ABC_trans_N PF14510.6 KKK21251.1 - 1.1e-19 70.8 0.1 3.2e-19 69.3 0.1 1.8 1 0 0 1 1 1 1 ABC-transporter N-terminal RsgA_GTPase PF03193.16 KKK21251.1 - 8.9e-07 29.0 0.1 0.00019 21.4 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_25 PF13481.6 KKK21251.1 - 2e-06 27.6 0.1 2.5e-05 23.9 0.0 2.5 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 KKK21251.1 - 8.1e-06 26.3 1.6 0.0015 18.9 0.1 2.9 3 0 0 3 3 2 1 AAA ATPase domain AAA_29 PF13555.6 KKK21251.1 - 0.00073 19.2 2.0 0.021 14.6 0.2 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_18 PF13238.6 KKK21251.1 - 0.0011 19.6 0.0 0.056 14.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 KKK21251.1 - 0.0011 18.9 0.0 2.1 8.1 0.1 2.9 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_33 PF13671.6 KKK21251.1 - 0.0011 19.1 0.1 0.078 13.1 0.1 2.6 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 KKK21251.1 - 0.0026 17.2 0.0 0.34 10.3 0.0 3.2 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KKK21251.1 - 0.0066 16.7 1.7 0.87 9.9 0.1 3.1 3 0 0 3 3 3 1 AAA domain AAA_30 PF13604.6 KKK21251.1 - 0.016 15.0 0.1 1.7 8.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain Ploopntkinase3 PF18751.1 KKK21251.1 - 0.025 14.5 0.1 0.39 10.6 0.0 2.2 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 RNA_helicase PF00910.22 KKK21251.1 - 0.026 14.9 0.0 11 6.5 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA_17 PF13207.6 KKK21251.1 - 0.063 13.7 0.2 4 7.9 0.0 2.8 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 KKK21251.1 - 0.11 12.6 0.0 26 4.9 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase Viral_helicase1 PF01443.18 KKK21251.1 - 0.14 11.9 0.0 4.9 6.8 0.0 2.3 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_28 PF13521.6 KKK21251.1 - 0.14 12.4 0.0 1.8 8.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KKK21251.1 - 0.18 11.5 0.2 12 5.6 0.2 2.6 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KKK21251.1 - 0.19 11.7 6.5 2.9 7.8 0.2 3.5 4 0 0 4 4 4 0 NACHT domain cobW PF02492.19 KKK21251.1 - 0.22 11.1 3.0 0.42 10.2 0.1 2.5 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain DUF2569 PF10754.9 KKK21251.1 - 0.86 10.0 6.9 2 8.8 6.9 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2569) DUF1761 PF08570.10 KKK21251.1 - 2.1 8.6 8.8 2.3 8.5 2.6 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1761) ABC2_membrane_3 PF12698.7 KKK21251.1 - 9.8 5.2 21.5 27 3.7 21.5 1.7 1 1 0 1 1 1 0 ABC-2 family transporter protein LSM PF01423.22 KKK21252.1 - 6.8e-22 76.9 0.3 8.5e-22 76.6 0.3 1.1 1 0 0 1 1 1 1 LSM domain FoP_duplication PF13865.6 KKK21252.1 - 0.014 16.0 8.8 0.02 15.4 8.8 1.3 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 SM-ATX PF14438.6 KKK21252.1 - 0.056 13.6 0.0 0.073 13.2 0.0 1.3 1 0 0 1 1 1 0 Ataxin 2 SM domain Pan3_PK PF18101.1 KKK21253.1 - 7.8e-63 210.5 0.1 1.2e-62 209.9 0.1 1.3 1 0 0 1 1 1 1 Pan3 Pseudokinase domain Pkinase PF00069.25 KKK21253.1 - 5.1e-06 26.0 0.0 8.3e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain UBA_4 PF14555.6 KKK21254.1 - 4.8e-09 35.9 0.0 1.1e-08 34.7 0.0 1.7 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.20 KKK21254.1 - 5.4e-09 36.1 0.0 1.2e-08 35.0 0.0 1.5 1 0 0 1 1 1 1 UBX domain Atg14 PF10186.9 KKK21254.1 - 0.12 11.4 8.6 0.18 10.8 8.6 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 FUSC_2 PF13515.6 KKK21254.1 - 0.18 11.9 0.0 0.33 11.1 0.0 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein-like DUF1682 PF07946.14 KKK21254.1 - 0.79 8.9 8.5 1.3 8.2 8.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Ribosomal_S15 PF00312.22 KKK21286.1 - 3.1e-27 94.6 2.0 1.3e-26 92.6 0.4 2.7 2 1 1 3 3 3 1 Ribosomal protein S15 Red1 PF07964.11 KKK21287.1 - 0.0076 14.6 20.9 0.0089 14.3 20.9 1.1 1 0 0 1 1 1 1 Rec10 / Red1 Mitofilin PF09731.9 KKK21287.1 - 0.4 9.5 18.3 0.48 9.2 18.3 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein SWI-SNF_Ssr4 PF08549.10 KKK21287.1 - 0.8 8.3 16.4 1 7.9 16.4 1.0 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) SOBP PF15279.6 KKK21287.1 - 1.5 9.3 23.9 1.8 9.1 23.9 1.0 1 0 0 1 1 1 0 Sine oculis-binding protein RR_TM4-6 PF06459.12 KKK21287.1 - 3.4 7.4 17.1 4.8 6.9 17.1 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Ribosomal_S2 PF00318.20 KKK21288.1 - 3.3e-26 91.9 0.1 5e-15 55.3 0.1 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 40S_SA_C PF16122.5 KKK21288.1 - 8.1e-07 30.3 16.5 1.5e-06 29.4 16.5 1.4 1 0 0 1 1 1 1 40S ribosomal protein SA C-terminus HsbA PF12296.8 KKK21289.1 - 5.7e-26 91.3 13.3 5.7e-26 91.3 13.3 2.5 2 0 0 2 2 2 1 Hydrophobic surface binding protein A NPV_P10 PF05531.12 KKK21289.1 - 0.62 10.6 5.8 5.4 7.5 5.8 2.5 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein RIFIN PF02009.16 KKK21289.1 - 1.6 8.6 10.9 2.4 8.0 10.9 1.2 1 0 0 1 1 1 0 Rifin Copper-fist PF00649.18 KKK21290.1 - 2.1e-17 62.3 0.5 7.3e-17 60.6 0.5 2.0 1 0 0 1 1 1 1 Copper fist DNA binding domain APH PF01636.23 KKK21291.1 - 2.7e-08 34.1 0.0 3.8e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Glyco_hydro_15 PF00723.21 KKK21292.1 - 8.1e-108 361.1 0.2 8.1e-108 361.1 0.2 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 15 CBM_20 PF00686.19 KKK21292.1 - 1.4e-32 111.4 0.1 3.9e-32 110.0 0.1 1.8 1 0 0 1 1 1 1 Starch binding domain tRNA_bind PF01588.20 KKK21293.1 - 6.6e-21 74.2 0.0 4.9e-20 71.5 0.0 2.2 1 1 0 1 1 1 1 Putative tRNA binding domain GST_C_2 PF13410.6 KKK21293.1 - 6.1e-05 23.0 0.0 0.00012 22.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KKK21293.1 - 0.0014 18.8 0.0 0.0014 18.8 0.0 2.8 2 1 1 3 3 3 1 Glutathione S-transferase, C-terminal domain tRNA-synt_1b PF00579.25 KKK21294.1 - 4.6e-24 85.2 0.0 8.6e-24 84.4 0.0 1.4 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) PIN_12 PF16289.5 KKK21294.1 - 0.12 12.9 0.5 0.63 10.5 0.0 2.2 2 0 0 2 2 2 0 PIN domain FAA_hydrolase PF01557.18 KKK21295.1 - 2.8e-52 177.5 0.0 3.9e-52 177.1 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family DUF3712 PF12505.8 KKK21296.1 - 1.1e-33 116.2 0.4 2.4e-33 115.1 0.4 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3712) Adenyl_transf PF04439.12 KKK21296.1 - 0.14 11.2 0.1 0.21 10.6 0.1 1.1 1 0 0 1 1 1 0 Streptomycin adenylyltransferase adh_short_C2 PF13561.6 KKK21297.1 - 7.7e-55 186.0 0.0 9.9e-55 185.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KKK21297.1 - 1.2e-50 171.7 0.1 1.9e-50 171.0 0.0 1.3 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 KKK21297.1 - 8e-09 35.7 0.1 1.5e-08 34.7 0.0 1.5 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 KKK21297.1 - 8.2e-06 25.4 0.0 1.3e-05 24.8 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KKK21297.1 - 0.0028 17.1 0.0 0.0039 16.6 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase ADH_zinc_N PF00107.26 KKK21297.1 - 0.012 15.6 0.0 0.021 14.8 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase RmlD_sub_bind PF04321.17 KKK21297.1 - 0.08 12.0 0.0 0.17 11.0 0.0 1.5 1 0 0 1 1 1 0 RmlD substrate binding domain Fungal_trans PF04082.18 KKK21298.1 - 2.9e-25 88.8 2.0 4.4e-25 88.2 2.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK21298.1 - 1.7e-06 28.1 6.7 3.6e-06 27.0 6.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3425 PF11905.8 KKK21299.1 - 3.5e-23 81.9 0.0 5.4e-23 81.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) FAM199X PF15814.5 KKK21299.1 - 0.025 13.6 0.1 0.035 13.2 0.1 1.2 1 0 0 1 1 1 0 Protein family FAM199X bZIP_1 PF00170.21 KKK21299.1 - 0.041 14.0 8.6 0.1 12.7 8.6 1.6 1 0 0 1 1 1 0 bZIP transcription factor CSTF1_dimer PF16699.5 KKK21299.1 - 0.18 11.6 0.1 0.33 10.7 0.1 1.3 1 0 0 1 1 1 0 Cleavage stimulation factor subunit 1, dimerisation domain Rad4 PF03835.15 KKK21300.1 - 4.4e-35 120.5 0.1 1.6e-34 118.7 0.0 2.0 2 0 0 2 2 2 1 Rad4 transglutaminase-like domain BHD_3 PF10405.9 KKK21300.1 - 9.3e-29 99.7 0.4 2.8e-28 98.1 0.4 1.9 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.9 KKK21300.1 - 1.2e-21 76.3 0.0 2.4e-21 75.3 0.0 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.9 KKK21300.1 - 9.4e-17 61.7 0.2 9.4e-17 61.7 0.2 3.3 3 1 0 3 3 3 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.19 KKK21300.1 - 0.018 15.5 0.0 0.072 13.5 0.0 2.1 1 0 0 1 1 1 0 Transglutaminase-like superfamily Geminin PF07412.12 KKK21300.1 - 0.023 14.5 0.9 0.068 12.9 0.9 1.8 1 0 0 1 1 1 0 Geminin Beta-lactamase PF00144.24 KKK21301.1 - 1.2e-44 152.9 0.2 1.7e-44 152.4 0.2 1.1 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.8 KKK21301.1 - 3.9e-12 46.5 0.0 1.2e-11 45.0 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3471) Peptidase_S9 PF00326.21 KKK21302.1 - 1.2e-39 136.0 0.8 1.7e-39 135.5 0.8 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.18 KKK21302.1 - 1.7e-11 44.1 0.1 7.2e-11 42.0 0.1 1.9 1 1 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S15 PF02129.18 KKK21302.1 - 1.2e-09 38.2 3.9 1e-05 25.3 2.2 2.4 1 1 0 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.8 KKK21302.1 - 9.2e-08 31.6 2.5 0.0012 18.1 0.0 2.5 3 0 0 3 3 3 2 Serine aminopeptidase, S33 BAAT_C PF08840.11 KKK21302.1 - 8.1e-07 29.2 0.1 7.6e-06 26.0 0.1 2.1 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_1 PF00561.20 KKK21302.1 - 1.6e-06 28.0 0.4 0.013 15.2 0.0 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 KKK21302.1 - 2.1e-05 24.6 0.0 0.00024 21.2 0.0 2.2 2 0 0 2 2 2 1 TAP-like protein PD40 PF07676.12 KKK21302.1 - 2.3e-05 24.2 2.2 0.00029 20.7 0.6 2.8 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat Abhydrolase_3 PF07859.13 KKK21302.1 - 5.6e-05 23.1 2.3 0.0005 20.0 2.3 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 KKK21302.1 - 0.00062 19.6 0.1 0.046 13.5 0.0 2.3 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase DUF829 PF05705.14 KKK21302.1 - 0.0073 16.2 0.0 0.011 15.7 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Esterase_phd PF10503.9 KKK21302.1 - 0.0073 15.8 0.8 0.049 13.1 0.5 2.4 2 1 0 2 2 2 1 Esterase PHB depolymerase COesterase PF00135.28 KKK21302.1 - 0.043 12.7 0.1 0.065 12.1 0.1 1.2 1 0 0 1 1 1 0 Carboxylesterase family FSH1 PF03959.13 KKK21302.1 - 0.049 13.3 0.0 0.087 12.5 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) LIP PF03583.14 KKK21302.1 - 0.068 12.5 1.9 2.2 7.5 0.0 2.2 2 0 0 2 2 2 0 Secretory lipase MFS_1 PF07690.16 KKK21304.1 - 1.3e-14 54.0 48.2 1.4e-08 34.0 26.4 2.6 2 1 1 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.13 KKK21304.1 - 2e-08 33.2 21.1 5.7e-07 28.3 21.4 2.2 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) GtrA PF04138.14 KKK21304.1 - 0.00049 20.3 7.5 0.00049 20.3 7.5 3.8 4 2 0 4 4 4 1 GtrA-like protein Trp_oprn_chp PF09534.10 KKK21304.1 - 0.03 14.1 0.4 0.03 14.1 0.4 2.1 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF3040 PF11239.8 KKK21304.1 - 0.12 12.6 0.3 0.12 12.6 0.3 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF3040) zf-H2C2 PF09337.10 KKK21305.1 - 3.3e-17 62.4 2.3 7e-17 61.4 2.3 1.6 1 0 0 1 1 1 1 H2C2 zinc finger Integrase_H2C2 PF17921.1 KKK21305.1 - 3.6e-10 39.8 1.1 1.2e-09 38.1 1.1 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain Acetyltransf_1 PF00583.25 KKK21305.1 - 9.5e-07 29.1 0.0 1.6e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 KKK21305.1 - 0.0027 17.6 0.0 0.0053 16.7 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 KKK21305.1 - 0.0038 17.9 0.1 0.0088 16.7 0.1 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KKK21305.1 - 0.067 13.3 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Sugar_tr PF00083.24 KKK21306.1 - 1e-79 268.6 21.0 1.2e-79 268.3 21.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKK21306.1 - 7.2e-25 87.7 31.8 1.1e-23 83.7 31.8 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KKK21306.1 - 1.3e-07 30.4 2.2 2.1e-07 29.8 2.2 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Beta-lactamase PF00144.24 KKK21307.1 - 1.3e-28 100.3 1.1 2e-28 99.6 1.1 1.2 1 0 0 1 1 1 1 Beta-lactamase HK PF02110.15 KKK21308.1 - 4.7e-79 265.2 0.3 4.7e-79 265.2 0.3 1.8 2 1 1 3 3 3 1 Hydroxyethylthiazole kinase family TMP-TENI PF02581.17 KKK21308.1 - 1.3e-57 194.1 2.4 2.1e-57 193.4 2.4 1.4 1 0 0 1 1 1 1 Thiamine monophosphate synthase Carb_kinase PF01256.17 KKK21308.1 - 0.0065 16.0 0.0 0.02 14.4 0.0 1.7 1 0 0 1 1 1 1 Carbohydrate kinase Cerato-platanin PF07249.12 KKK21309.1 - 6.9e-27 93.9 2.4 1.5e-24 86.4 2.4 2.0 1 1 0 1 1 1 1 Cerato-platanin Glyco_hydro_16 PF00722.21 KKK21310.1 - 2.8e-07 30.2 0.0 4.8e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 zf-C2H2 PF00096.26 KKK21318.1 - 2e-12 46.8 11.8 2.1e-06 27.9 0.4 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KKK21318.1 - 6.5e-08 32.8 10.1 0.0021 18.7 0.3 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KKK21318.1 - 1.2e-07 31.8 10.4 7.6e-07 29.3 4.1 3.4 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KKK21318.1 - 3.1e-05 24.1 3.9 0.011 16.0 0.5 2.4 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KKK21318.1 - 3.4e-05 24.1 4.1 0.0075 16.6 0.3 2.7 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KKK21318.1 - 0.0001 22.2 8.7 0.0055 16.7 0.5 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf_C2H2_ZHX PF18387.1 KKK21318.1 - 0.00043 19.9 3.8 0.15 11.8 0.2 2.8 1 1 1 2 2 2 2 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_3rep PF18868.1 KKK21318.1 - 0.19 12.4 3.0 3.3 8.4 0.5 2.8 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-BED PF02892.15 KKK21318.1 - 0.22 11.6 6.0 0.08 13.0 2.0 2.1 1 1 1 2 2 2 0 BED zinc finger zf-C2H2_11 PF16622.5 KKK21318.1 - 0.63 9.9 7.8 10 6.0 0.0 2.6 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-LYAR PF08790.11 KKK21318.1 - 0.76 9.7 4.7 17 5.4 0.1 3.0 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger zf-C2HE PF16278.5 KKK21318.1 - 0.86 10.1 6.9 95 3.6 6.9 2.6 1 1 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_2 PF12756.7 KKK21318.1 - 0.87 10.0 3.7 12 6.3 0.4 2.4 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Diphthami_syn_2 PF01902.17 KKK21319.1 - 4.8e-12 45.9 0.0 1.7e-05 24.4 0.0 3.7 3 1 1 4 4 4 2 Diphthamide synthase Myc_N PF01056.18 KKK21319.1 - 0.0045 16.9 0.8 0.0066 16.4 0.8 1.1 1 0 0 1 1 1 1 Myc amino-terminal region Ribosomal_60s PF00428.19 KKK21319.1 - 0.037 14.6 2.7 0.099 13.2 2.7 1.8 1 0 0 1 1 1 0 60s Acidic ribosomal protein DUF4611 PF15387.6 KKK21319.1 - 0.28 11.4 4.9 0.15 12.3 2.6 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Aldo_ket_red PF00248.21 KKK21321.1 - 4.9e-40 137.5 0.0 6.4e-40 137.2 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family TEA PF01285.18 KKK21322.1 - 3.1e-28 97.6 0.0 7.5e-28 96.4 0.0 1.7 1 0 0 1 1 1 1 TEA/ATTS domain RRM_1 PF00076.22 KKK21323.1 - 9.4e-75 246.4 1.0 1.5e-19 69.6 0.0 5.5 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KKK21323.1 - 4.8e-08 32.7 0.0 0.017 14.7 0.0 4.0 4 1 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KKK21323.1 - 7.8e-07 29.0 0.0 0.61 10.1 0.0 4.4 5 0 0 5 5 5 3 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 KKK21323.1 - 0.00016 21.7 0.1 5.7 7.1 0.0 3.9 3 0 0 3 3 3 2 RNA recognition motif RRM_occluded PF16842.5 KKK21323.1 - 0.00039 20.2 0.0 1.4 8.8 0.0 4.0 4 0 0 4 4 4 2 Occluded RNA-recognition motif Limkain-b1 PF11608.8 KKK21323.1 - 0.015 15.4 0.1 35 4.6 0.0 4.6 5 0 0 5 5 5 0 Limkain b1 Dynein_light PF01221.18 KKK21324.1 - 7.2e-37 125.6 5.3 1.4e-36 124.6 5.3 1.4 1 1 0 1 1 1 1 Dynein light chain type 1 DUF4723 PF15851.5 KKK21324.1 - 0.0053 16.9 0.0 0.0076 16.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4723) SYCP2_SLD PF18584.1 KKK21324.1 - 0.024 14.9 0.3 0.035 14.3 0.3 1.3 1 0 0 1 1 1 0 Synaptonemal complex 2 Spt16M-like domain Phage_B PF02304.15 KKK21324.1 - 0.039 14.3 0.1 0.047 14.1 0.1 1.2 1 0 0 1 1 1 0 Scaffold protein B RhoGEF67_u1 PF16615.5 KKK21324.1 - 0.059 13.9 0.1 0.099 13.2 0.1 1.3 1 0 0 1 1 1 0 Unstructured region one on RhoGEF 6 and 7 Response_reg PF00072.24 KKK21341.1 - 9.6e-22 77.3 0.1 1.8e-21 76.4 0.1 1.5 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 KKK21341.1 - 1e-21 77.5 0.4 3.2e-21 75.9 0.0 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 KKK21341.1 - 1.7e-16 60.0 0.1 5.2e-16 58.4 0.1 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_3 PF08447.12 KKK21341.1 - 7.5e-11 42.2 2.4 0.00037 20.7 0.2 3.9 3 0 0 3 3 3 3 PAS fold PAS_4 PF08448.10 KKK21341.1 - 9.9e-06 25.8 0.1 4.3e-05 23.7 0.1 2.1 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.7 KKK21341.1 - 0.00063 20.0 0.0 0.25 11.6 0.0 3.7 3 1 0 3 3 3 1 PAS domain PAS PF00989.25 KKK21341.1 - 0.0047 16.9 0.0 0.43 10.6 0.0 2.8 2 0 0 2 2 2 1 PAS fold MotA_ExbB PF01618.16 KKK21341.1 - 0.081 12.7 0.0 0.2 11.4 0.0 1.6 1 0 0 1 1 1 0 MotA/TolQ/ExbB proton channel family DUF3256 PF11644.8 KKK21341.1 - 0.12 11.9 0.2 0.26 10.8 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3256) HSP70 PF00012.20 KKK21361.1 - 1.8e-85 287.4 0.8 2.4e-85 287.0 0.8 1.1 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KKK21361.1 - 8.1e-11 41.3 0.2 1.2e-10 40.8 0.2 1.3 1 0 0 1 1 1 1 MreB/Mbl protein Peripla_BP_6 PF13458.6 KKK21361.1 - 0.012 15.3 1.3 0.084 12.5 0.4 2.1 1 1 0 2 2 2 0 Periplasmic binding protein Myb_DNA-bind_6 PF13921.6 KKK21362.1 - 7e-17 61.4 1.4 9.5e-11 41.8 0.4 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KKK21362.1 - 7.9e-17 61.2 5.2 6.4e-10 39.1 0.2 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 KKK21362.1 - 0.0056 17.0 1.2 0.03 14.7 1.2 2.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 KKK21362.1 - 0.014 15.7 1.8 3.5 8.0 0.4 3.1 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Ribosomal_S14 PF00253.21 KKK21363.1 - 2.5e-21 75.2 0.5 7.5e-21 73.6 0.1 1.8 2 0 0 2 2 2 1 Ribosomal protein S14p/S29e TauD PF02668.16 KKK21364.1 - 6.1e-16 59.0 0.0 3.5e-07 30.3 0.0 2.2 1 1 1 2 2 2 2 Taurine catabolism dioxygenase TauD, TfdA family HAD_2 PF13419.6 KKK21364.1 - 1.2e-12 48.3 0.0 2.2e-12 47.4 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KKK21364.1 - 1.6e-08 34.5 0.1 3.8e-08 33.3 0.1 1.6 2 0 0 2 2 2 1 HAD-hyrolase-like HAD PF12710.7 KKK21364.1 - 1.2e-06 29.1 0.1 3.7e-06 27.5 0.1 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KKK21364.1 - 1.4e-05 25.5 0.0 0.036 14.3 0.0 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase CsiD PF08943.10 KKK21364.1 - 0.0024 17.0 0.0 0.0044 16.2 0.0 1.4 1 0 0 1 1 1 1 CsiD Hydrolase_6 PF13344.6 KKK21364.1 - 0.16 12.1 0.0 50 4.1 0.0 3.0 3 0 0 3 3 3 0 Haloacid dehalogenase-like hydrolase Sugar_tr PF00083.24 KKK21365.1 - 1e-84 285.1 25.3 1.5e-62 212.0 9.0 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KKK21365.1 - 2.7e-19 69.3 34.0 1.9e-11 43.5 7.2 2.9 2 1 1 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.13 KKK21365.1 - 6.8e-05 21.5 1.3 6.8e-05 21.5 1.3 1.9 2 1 1 3 3 3 1 Fungal trichothecene efflux pump (TRI12) DASH_Spc19 PF08287.11 KKK21367.1 - 7.6e-53 178.6 7.7 1e-52 178.2 7.7 1.2 1 0 0 1 1 1 1 Spc19 Mur_ligase_M PF08245.12 KKK21367.1 - 0.04 13.9 0.0 0.051 13.6 0.0 1.3 1 1 0 1 1 1 0 Mur ligase middle domain NmrA PF05368.13 KKK21368.1 - 3.1e-47 161.1 0.1 3.5e-47 160.9 0.1 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KKK21368.1 - 1.8e-19 70.4 0.1 2.1e-19 70.1 0.1 1.1 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KKK21368.1 - 0.00019 20.6 0.1 0.00024 20.2 0.1 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.18 KKK21368.1 - 0.014 15.7 0.1 0.019 15.2 0.1 1.2 1 0 0 1 1 1 0 TrkA-N domain Rogdi_lz PF10259.9 KKK21370.1 - 5e-78 262.3 0.0 7.4e-78 261.7 0.0 1.3 1 0 0 1 1 1 1 Rogdi leucine zipper containing protein Rsm22 PF09243.10 KKK21370.1 - 2.2e-29 102.6 0.0 1e-28 100.4 0.0 2.0 1 1 0 1 1 1 1 Mitochondrial small ribosomal subunit Rsm22 SUR7 PF06687.12 KKK21371.1 - 1.6e-42 145.6 13.5 1.8e-42 145.4 13.5 1.0 1 0 0 1 1 1 1 SUR7/PalI family Clc-like PF07062.12 KKK21371.1 - 0.0092 15.5 3.0 0.015 14.8 3.0 1.4 1 0 0 1 1 1 1 Clc-like 30K_MP_C_Ter PF11330.8 KKK21371.1 - 0.22 10.8 0.1 0.38 10.1 0.0 1.4 2 0 0 2 2 2 0 C-Terminal of 30K viral movement proteins DUF373 PF04123.13 KKK21371.1 - 0.48 9.8 6.1 0.04 13.4 1.2 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF373) TIC20 PF16166.5 KKK21371.1 - 1.4 8.7 7.1 5.3 6.8 7.1 1.9 1 1 0 1 1 1 0 Chloroplast import apparatus Tic20-like Amastin PF07344.11 KKK21371.1 - 3.7 7.4 12.2 2.1 8.2 9.7 1.9 2 1 0 2 2 2 0 Amastin surface glycoprotein KH_6 PF15985.5 KKK21372.1 - 2.9e-17 62.7 0.0 5.6e-17 61.8 0.0 1.5 1 0 0 1 1 1 1 KH domain Rrp40_N PF18311.1 KKK21372.1 - 3.2e-12 46.2 1.6 8.3e-12 44.9 1.5 1.8 2 0 0 2 2 2 1 Exosome complex exonuclease Rrp40 N-terminal domain PerC PF06069.11 KKK21372.1 - 0.16 12.2 0.0 0.34 11.2 0.0 1.5 2 0 0 2 2 2 0 PerC transcriptional activator Glyco_transf_24 PF18404.1 KKK21373.1 - 5e-149 495.0 2.4 7.9e-149 494.4 0.8 2.1 2 0 0 2 2 2 1 Glucosyltransferase 24 Thioredoxin_14 PF18402.1 KKK21373.1 - 7.6e-66 222.7 0.0 9.2e-65 219.1 0.0 2.5 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_12 PF18400.1 KKK21373.1 - 1.8e-48 164.9 0.3 4.2e-48 163.7 0.0 1.8 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_13 PF18401.1 KKK21373.1 - 8e-45 152.1 2.1 8.1e-43 145.6 0.1 3.4 4 0 0 4 4 4 1 Thioredoxin-like domain Thioredoxin_15 PF18403.1 KKK21373.1 - 1.6e-43 149.2 0.0 1e-40 140.0 0.0 3.1 3 0 0 3 3 3 1 Thioredoxin-like domain UDP-g_GGTase PF06427.11 KKK21373.1 - 2.7e-42 143.3 0.0 5.3e-42 142.4 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Glyco_transf_8 PF01501.20 KKK21373.1 - 0.00051 19.7 0.0 0.0009 18.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 8 DS PF01916.17 KKK21374.1 - 3.1e-130 433.6 0.1 3.5e-130 433.4 0.1 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase DUF2483 PF10656.9 KKK21374.1 - 0.083 13.1 0.4 2.7 8.2 0.1 3.2 2 1 2 4 4 4 0 Hypothetical protein of unknown function (DUF2483) Aldedh PF00171.22 KKK21375.1 - 1.5e-128 429.3 0.0 9e-127 423.4 0.0 2.0 1 1 0 1 1 1 1 Aldehyde dehydrogenase family Glyco_hydro_2_C PF02836.17 KKK21376.1 - 1.5e-113 378.9 0.2 3.4e-104 348.2 0.0 2.6 2 1 0 2 2 2 2 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2_N PF02837.18 KKK21376.1 - 1.1e-57 194.7 1.2 7.8e-45 152.8 0.2 2.6 2 0 0 2 2 2 2 Glycosyl hydrolases family 2, sugar binding domain Bgal_small_N PF02929.17 KKK21376.1 - 2.3e-52 178.0 0.0 4.4e-52 177.1 0.0 1.4 1 0 0 1 1 1 1 Beta galactosidase small chain DUF4981 PF16353.5 KKK21376.1 - 1.3e-16 60.8 0.0 4.2e-16 59.2 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function(DUF4981) Glyco_hydro_2 PF00703.21 KKK21376.1 - 8.1e-13 49.0 0.6 7.9e-05 23.3 0.0 3.1 2 1 0 2 2 2 2 Glycosyl hydrolases family 2 tify PF06200.14 KKK21376.1 - 0.26 10.7 0.8 0.53 9.7 0.8 1.5 1 0 0 1 1 1 0 tify domain GMC_oxred_N PF00732.19 KKK21377.1 - 8.7e-52 176.3 0.0 1.2e-51 175.9 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KKK21377.1 - 3e-31 108.9 0.1 5.2e-31 108.1 0.1 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 KKK21377.1 - 2.1e-06 27.1 0.0 3.1e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 KKK21377.1 - 0.00013 22.1 0.1 0.00029 21.0 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KKK21377.1 - 0.00031 20.4 0.3 0.0014 18.3 0.3 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KKK21377.1 - 0.0025 17.1 0.0 0.0083 15.4 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KKK21377.1 - 0.0039 16.5 0.0 0.76 9.0 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KKK21377.1 - 0.01 15.0 0.0 0.8 8.7 0.0 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_binding_2 PF00890.24 KKK21377.1 - 0.014 14.5 0.0 0.024 13.8 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 KKK21377.1 - 0.046 12.4 0.0 0.14 10.9 0.0 1.7 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_9 PF13454.6 KKK21377.1 - 0.12 12.4 0.0 0.26 11.3 0.0 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding MFS_1 PF07690.16 KKK21378.1 - 1.6e-28 99.6 24.6 2.2e-28 99.2 24.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Glyco_hydro_88 PF07470.13 KKK21379.1 - 2.1e-93 313.2 7.4 2.4e-93 313.0 7.4 1.0 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Glyco_hydro_127 PF07944.12 KKK21379.1 - 0.00092 17.8 0.7 0.0013 17.4 0.2 1.5 2 0 0 2 2 2 1 Beta-L-arabinofuranosidase, GH127 Amidohydro_1 PF01979.20 KKK21380.1 - 9.7e-72 242.1 0.1 1.2e-71 241.9 0.1 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KKK21380.1 - 4.3e-21 75.9 0.3 3.4e-15 56.5 0.2 2.2 2 0 0 2 2 2 2 Amidohydrolase family A_deaminase PF00962.22 KKK21380.1 - 0.006 15.9 0.0 0.015 14.6 0.0 1.6 1 1 0 1 1 1 1 Adenosine/AMP deaminase SurE PF01975.17 KKK21381.1 - 6.2e-33 114.2 1.1 8.1e-33 113.8 1.1 1.1 1 0 0 1 1 1 1 Survival protein SurE Glyco_hydro_61 PF03443.14 KKK21382.1 - 2.2e-68 230.2 0.3 2.2e-68 230.2 0.3 1.8 2 0 0 2 2 2 1 Glycosyl hydrolase family 61 CBM_1 PF00734.18 KKK21382.1 - 1.1e-11 44.5 4.8 2.9e-11 43.1 4.8 1.8 1 0 0 1 1 1 1 Fungal cellulose binding domain NPP1 PF05630.11 KKK21383.1 - 1.8e-61 207.7 0.0 2e-61 207.5 0.0 1.0 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) RPE65 PF03055.15 KKK21384.1 - 7.2e-103 345.2 0.0 8.9e-103 344.9 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Pectate_lyase_3 PF12708.7 KKK21385.1 - 4.8e-63 212.9 17.8 2.4e-54 184.4 7.0 4.2 5 1 0 5 5 5 2 Pectate lyase superfamily protein SLT PF01464.20 KKK21385.1 - 0.0023 17.6 0.2 0.014 15.0 0.1 2.2 2 0 0 2 2 2 1 Transglycosylase SLT domain End_N_terminal PF12218.8 KKK21385.1 - 0.45 10.3 3.8 0.26 11.0 0.1 2.6 3 0 0 3 3 3 0 N terminal extension of bacteriophage endosialidase Glyco_hydro_18 PF00704.28 KKK21386.1 - 1.2e-31 110.7 0.0 5.5e-30 105.2 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 Dickkopf_N PF04706.12 KKK21387.1 - 0.24 11.9 25.4 0.66 10.5 12.8 2.8 1 1 1 2 2 2 0 Dickkopf N-terminal cysteine-rich region Aa_trans PF01490.18 KKK21388.1 - 2.5e-39 135.2 33.0 3.1e-39 134.9 33.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF1129 PF06570.11 KKK21388.1 - 5.9 6.3 14.7 0.058 12.9 2.7 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1129) Ferric_reduct PF01794.19 KKK21389.1 - 7.1e-22 77.8 13.6 7.1e-22 77.8 13.6 2.1 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KKK21389.1 - 1.8e-10 40.8 0.0 3.3e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 KKK21389.1 - 1.6e-07 31.6 0.0 2.3e-06 27.8 0.0 2.3 2 1 0 2 2 2 1 Ferric reductase NAD binding domain Ctr PF04145.15 KKK21390.1 - 4.2e-37 128.0 3.0 7.1e-37 127.3 3.0 1.4 1 0 0 1 1 1 1 Ctr copper transporter family DUF2164 PF09932.9 KKK21390.1 - 0.15 12.2 0.0 0.32 11.1 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2164) Aegerolysin PF06355.13 KKK21391.1 - 1.6e-42 144.7 0.0 1.9e-42 144.5 0.0 1.0 1 0 0 1 1 1 1 Aegerolysin Sugar_tr PF00083.24 KKK21392.1 - 3e-99 332.9 22.4 3.4e-99 332.7 22.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKK21392.1 - 5e-32 111.2 44.1 8.1e-29 100.6 25.0 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily MARVEL PF01284.23 KKK21392.1 - 2.8 8.0 15.2 0.11 12.6 1.4 2.8 2 0 0 2 2 2 0 Membrane-associating domain Zn_clus PF00172.18 KKK21393.1 - 1.1e-08 35.0 8.0 4.4e-08 33.1 8.0 2.1 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KKK21393.1 - 3.7e-07 29.5 1.6 9.1e-07 28.2 1.6 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Methyltransf_11 PF08241.12 KKK21394.1 - 1.4e-15 57.7 0.0 2.8e-15 56.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKK21394.1 - 3e-13 50.3 0.0 5.6e-13 49.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KKK21394.1 - 9.1e-08 32.1 0.0 2.3e-07 30.8 0.0 1.7 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KKK21394.1 - 1.2e-05 25.9 0.0 3.1e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KKK21394.1 - 1.8e-05 24.6 0.0 2.9e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 KKK21394.1 - 0.038 12.9 0.1 0.24 10.3 0.0 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1698) MetW PF07021.12 KKK21394.1 - 0.11 12.1 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW DnaB_bind PF10410.9 KKK21394.1 - 0.13 12.5 0.0 0.23 11.7 0.0 1.4 1 0 0 1 1 1 0 DnaB-helicase binding domain of primase MitMem_reg PF13012.6 KKK21395.1 - 1.5e-36 125.3 0.1 2.4e-36 124.6 0.1 1.3 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 KKK21395.1 - 9.6e-32 109.4 0.2 4.8e-31 107.2 0.0 2.0 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease tRNA_bind_2 PF13725.6 KKK21395.1 - 0.11 12.2 8.5 0.16 11.6 8.5 1.2 1 0 0 1 1 1 0 Possible tRNA binding domain Connexin PF00029.19 KKK21395.1 - 0.93 9.2 4.8 1.5 8.5 4.8 1.4 1 0 0 1 1 1 0 Connexin Folliculin PF11704.8 KKK21395.1 - 4.4 7.2 5.8 7.1 6.5 5.8 1.3 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport ADK PF00406.22 KKK21396.1 - 1.9e-60 203.3 0.1 2.5e-60 203.0 0.1 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 KKK21396.1 - 1.9e-23 83.4 0.8 3.3e-23 82.6 0.2 1.6 1 1 1 2 2 2 1 AAA domain ADK_lid PF05191.14 KKK21396.1 - 3.2e-18 65.4 0.0 7.7e-18 64.2 0.0 1.7 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.6 KKK21396.1 - 8.5e-06 26.3 0.0 1.4e-05 25.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KKK21396.1 - 0.00028 21.1 0.0 0.00042 20.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain ABC_tran_CTD PF16326.5 KKK21396.1 - 0.044 14.0 0.4 0.17 12.1 0.0 2.1 2 0 0 2 2 2 0 ABC transporter C-terminal domain AAA_24 PF13479.6 KKK21396.1 - 0.13 12.0 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain CFIA_Pcf11 PF11526.8 KKK21397.1 - 8e-09 35.9 1.5 2.7e-08 34.2 1.5 1.9 1 1 0 1 1 1 1 Subunit of cleavage factor IA Pcf11 zf-RRN7 PF11781.8 KKK21397.1 - 0.22 11.3 2.9 1.5 8.6 0.6 2.4 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 zf-C2HC_2 PF13913.6 KKK21397.1 - 2.6 8.0 6.5 15 5.7 0.2 2.3 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2H2_4 PF13894.6 KKK21397.1 - 3.1 8.9 3.8 29 5.8 0.3 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger zf_UBZ PF18439.1 KKK21397.1 - 9.7 5.9 8.0 16 5.2 2.7 2.8 2 1 0 2 2 2 0 Ubiquitin-Binding Zinc Finger GFO_IDH_MocA PF01408.22 KKK21398.1 - 1.9e-16 61.0 0.1 3.1e-16 60.3 0.1 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KKK21398.1 - 0.0067 16.4 0.0 0.014 15.4 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.16 KKK21398.1 - 0.17 12.5 0.1 0.29 11.8 0.1 1.3 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain AMP-binding PF00501.28 KKK21404.1 - 2e-06 26.7 0.0 8.1e-06 24.7 0.0 1.8 1 1 0 1 1 1 1 AMP-binding enzyme Hid1 PF12722.7 KKK21405.1 - 0 1106.8 0.0 0 1106.6 0.0 1.0 1 0 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.9 KKK21405.1 - 9.3e-107 358.0 0.0 1.2e-106 357.7 0.0 1.0 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein NPCC PF08058.11 KKK21405.1 - 4.5e-23 81.7 0.0 9.9e-23 80.6 0.0 1.6 1 0 0 1 1 1 1 Nuclear pore complex component DASH_Spc19 PF08287.11 KKK21405.1 - 0.0099 15.8 0.1 0.023 14.6 0.1 1.6 1 0 0 1 1 1 1 Spc19 BC10 PF06726.12 KKK21405.1 - 0.086 13.1 0.2 0.36 11.1 0.1 2.2 2 0 0 2 2 2 0 Bladder cancer-related protein BC10 HAT_KAT11 PF08214.11 KKK21407.1 - 3.5e-109 365.3 0.0 6.7e-109 364.4 0.0 1.4 2 0 0 2 2 2 1 Histone acetylation protein DUF4820 PF16091.5 KKK21409.1 - 0.015 14.7 0.1 0.024 14.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) HCO3_cotransp PF00955.21 KKK21409.1 - 0.17 10.7 0.1 0.27 10.0 0.1 1.2 1 0 0 1 1 1 0 HCO3- transporter family Hydrolase PF00702.26 KKK21410.1 - 4.8e-15 56.4 0.0 1.2e-11 45.3 0.0 2.1 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KKK21410.1 - 9.6e-15 55.1 0.0 1.7e-14 54.3 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KKK21410.1 - 3.9e-06 26.8 0.1 1.2e-05 25.3 0.1 1.8 3 0 0 3 3 3 1 HAD-hyrolase-like HAD PF12710.7 KKK21410.1 - 0.00015 22.2 0.0 0.00067 20.1 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.10 KKK21410.1 - 0.0053 16.4 0.0 0.21 11.2 0.0 2.6 2 1 0 2 2 2 1 Mitochondrial PGP phosphatase Hydrolase_6 PF13344.6 KKK21410.1 - 0.027 14.6 0.0 0.09 12.9 0.0 1.9 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase GHMP_kinases_N PF00288.26 KKK21412.1 - 0.025 14.8 4.4 0.025 14.8 4.4 2.4 3 0 0 3 3 3 0 GHMP kinases N terminal domain Sporozoite_P67 PF05642.11 KKK21412.1 - 0.046 11.8 0.5 0.059 11.5 0.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DctQ PF04290.12 KKK21412.1 - 0.34 10.8 7.9 0.035 14.0 2.6 1.9 2 0 0 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component Serglycin PF04360.12 KKK21412.1 - 1.7 8.6 3.6 0.59 10.1 0.2 1.9 2 0 0 2 2 2 0 Serglycin ING PF12998.7 KKK21413.1 - 1.6e-11 44.6 0.0 3.3e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 KKK21413.1 - 1.8e-06 27.7 7.2 3.1e-06 27.0 7.2 1.4 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 KKK21413.1 - 0.059 13.6 1.6 0.12 12.6 1.6 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain CD99L2 PF12301.8 KKK21413.1 - 0.076 13.3 0.3 0.076 13.3 0.3 2.6 2 1 0 2 2 2 0 CD99 antigen like protein 2 DUF4378 PF14309.6 KKK21413.1 - 0.15 12.4 0.1 0.46 10.8 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4378) PHD_2 PF13831.6 KKK21413.1 - 0.54 9.9 2.7 1 8.9 2.7 1.4 1 0 0 1 1 1 0 PHD-finger Abhydrolase_1 PF00561.20 KKK21416.1 - 3.3e-12 46.6 0.0 2.1e-11 44.0 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KKK21416.1 - 0.002 17.4 0.0 0.015 14.6 0.0 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KKK21416.1 - 0.014 16.0 0.0 0.031 14.9 0.0 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family PAP_central PF04928.17 KKK21417.1 - 5.7e-109 362.9 0.0 7.3e-109 362.5 0.0 1.1 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 KKK21417.1 - 6.9e-60 201.6 0.0 1.1e-59 200.9 0.0 1.3 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 KKK21417.1 - 3e-12 46.7 0.0 6e-12 45.7 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain PBP_like_2 PF12849.7 KKK21418.1 - 1.2e-09 38.3 1.7 4.4e-09 36.4 1.3 2.0 1 1 1 2 2 2 1 PBP superfamily domain AAL_decarboxy PF03306.13 KKK21418.1 - 0.042 13.2 0.0 2.6 7.3 0.0 2.4 2 0 0 2 2 2 0 Alpha-acetolactate decarboxylase LysR_substrate PF03466.20 KKK21418.1 - 0.049 13.0 0.0 0.089 12.1 0.0 1.3 1 0 0 1 1 1 0 LysR substrate binding domain MgrB PF13998.6 KKK21419.1 - 2.4 8.1 4.7 1.3 9.0 0.9 2.5 2 0 0 2 2 2 0 MgrB protein PHY PF00360.20 KKK21420.1 - 4e-27 94.7 0.0 8.3e-27 93.7 0.0 1.4 1 0 0 1 1 1 1 Phytochrome region HATPase_c PF02518.26 KKK21420.1 - 3.8e-19 69.2 0.1 1.5e-18 67.3 0.1 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KKK21420.1 - 1.1e-17 64.2 0.1 4.6e-17 62.2 0.0 2.2 2 0 0 2 2 2 1 Response regulator receiver domain GAF PF01590.26 KKK21420.1 - 2.6e-10 41.1 0.3 1.5e-09 38.5 0.0 2.6 3 0 0 3 3 3 1 GAF domain HisKA PF00512.25 KKK21420.1 - 1.3e-09 37.9 1.0 4e-09 36.4 0.4 2.2 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_2 PF08446.11 KKK21420.1 - 1.5e-09 38.5 0.0 3.6e-08 34.0 0.0 3.1 3 0 0 3 3 3 1 PAS fold HATPase_c_2 PF13581.6 KKK21420.1 - 0.0065 16.4 0.0 0.018 15.0 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain p450 PF00067.22 KKK21421.1 - 3.2e-74 250.3 0.0 4e-74 250.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF485 PF04341.12 KKK21421.1 - 0.17 11.8 0.3 18 5.3 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF485 3HCDH_N PF02737.18 KKK21422.1 - 1.8e-24 86.6 0.0 2.9e-24 85.9 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 KKK21422.1 - 4e-19 69.0 0.0 6.3e-19 68.4 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain ApbA PF02558.16 KKK21422.1 - 0.015 14.9 0.0 0.023 14.3 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.18 KKK21422.1 - 0.022 15.0 0.0 0.062 13.6 0.0 1.8 1 1 0 1 1 1 0 TrkA-N domain AlaDh_PNT_C PF01262.21 KKK21422.1 - 0.093 12.0 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain MFS_1 PF07690.16 KKK21423.1 - 2.1e-33 115.7 31.1 3e-33 115.2 31.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Claudin_2 PF13903.6 KKK21423.1 - 2.8 7.7 7.7 2.2 8.0 2.3 2.7 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction Fungal_trans PF04082.18 KKK21425.1 - 9.4e-23 80.6 0.1 1.7e-22 79.7 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK21425.1 - 7.9e-09 35.5 11.8 1.3e-08 34.8 11.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Lzipper-MIP1 PF14389.6 KKK21425.1 - 0.12 12.7 0.8 0.41 11.0 0.2 2.2 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 Cep57_CLD_2 PF14197.6 KKK21425.1 - 0.13 12.4 1.0 0.24 11.5 1.0 1.4 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 Pox_A_type_inc PF04508.12 KKK21425.1 - 5.3 7.1 7.8 14 5.7 7.8 1.7 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat MCRA PF06100.11 KKK21426.1 - 2e-153 511.8 0.0 8.9e-153 509.6 0.0 1.7 1 1 0 1 1 1 1 MCRA family NAD_binding_8 PF13450.6 KKK21426.1 - 5.8e-05 23.2 0.1 0.00015 22.0 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KKK21426.1 - 0.12 12.3 0.2 0.29 11.1 0.1 1.7 2 0 0 2 2 2 0 FAD-NAD(P)-binding DAO PF01266.24 KKK21426.1 - 0.18 11.4 0.0 1.1 8.7 0.1 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase Rota_NS35 PF02509.14 KKK21426.1 - 0.19 10.7 0.0 0.28 10.1 0.0 1.1 1 0 0 1 1 1 0 Rotavirus non-structural protein 35 Melibiase PF02065.18 KKK21427.1 - 2.9e-145 483.6 0.0 3.7e-145 483.2 0.0 1.1 1 0 0 1 1 1 1 Melibiase Glyco_hydro_36N PF16875.5 KKK21427.1 - 4.1e-82 275.6 0.0 5.5e-82 275.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 36 N-terminal domain Glyco_hydro_36C PF16874.5 KKK21427.1 - 7.9e-20 71.1 0.0 1.6e-19 70.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 36 C-terminal domain GHL10 PF02638.15 KKK21427.1 - 0.00021 20.5 0.0 0.00032 19.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase-like 10 GMC_oxred_N PF00732.19 KKK21428.1 - 1.2e-60 205.4 0.0 1.6e-60 205.0 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KKK21428.1 - 2.3e-32 112.5 0.4 6.5e-32 111.0 0.2 1.9 2 0 0 2 2 2 1 GMC oxidoreductase Lycopene_cycl PF05834.12 KKK21428.1 - 5.7e-05 22.3 0.1 0.00012 21.3 0.1 1.5 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 KKK21428.1 - 0.00047 19.3 0.2 0.11 11.6 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 KKK21428.1 - 0.0095 15.5 0.5 0.025 14.2 0.5 1.7 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 KKK21428.1 - 0.01 15.1 0.1 0.041 13.1 0.1 2.0 2 0 0 2 2 2 1 Thi4 family Pyr_redox_3 PF13738.6 KKK21428.1 - 0.02 14.2 0.7 2.9 7.1 0.5 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KKK21428.1 - 0.02 15.1 0.0 0.046 13.9 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KKK21428.1 - 0.047 12.9 0.1 0.37 10.0 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF3837 PF12939.7 KKK21428.1 - 0.12 12.8 0.1 0.88 10.0 0.2 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF3837) TrkA_N PF02254.18 KKK21428.1 - 0.21 11.8 0.5 0.67 10.2 0.1 2.1 3 0 0 3 3 3 0 TrkA-N domain Abhydrolase_1 PF00561.20 KKK21429.1 - 1.9e-14 53.9 0.0 2.2e-14 53.7 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KKK21429.1 - 4e-06 27.6 0.9 5.8e-06 27.1 0.9 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KKK21429.1 - 0.0005 19.4 0.0 0.00072 18.9 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 CFEM PF05730.11 KKK21430.1 - 0.00022 21.2 4.8 0.00049 20.1 4.8 1.6 1 0 0 1 1 1 1 CFEM domain FUSC_2 PF13515.6 KKK21430.1 - 0.96 9.6 8.2 0.11 12.6 2.6 2.3 1 1 1 2 2 2 0 Fusaric acid resistance protein-like ADH_N PF08240.12 KKK21431.1 - 4.8e-24 84.3 0.1 9e-24 83.5 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KKK21431.1 - 5.1e-15 55.6 0.0 1.1e-14 54.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 KKK21431.1 - 2.8e-05 23.6 0.1 6e-05 22.5 0.1 1.5 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 KKK21431.1 - 3e-05 23.4 0.1 5e-05 22.7 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 KKK21431.1 - 0.0057 16.6 0.1 0.011 15.6 0.0 1.5 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 KKK21431.1 - 0.022 15.0 0.0 0.04 14.1 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Ank_2 PF12796.7 KKK21432.1 - 2.8e-61 204.1 6.3 2.7e-11 43.9 0.2 7.0 2 2 4 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KKK21432.1 - 3e-47 158.4 8.6 4.3e-13 49.5 0.1 9.6 5 2 4 9 9 9 8 Ankyrin repeats (many copies) Ank_5 PF13857.6 KKK21432.1 - 1.5e-37 127.2 11.4 1.5e-08 34.7 0.0 10.3 3 2 9 12 12 12 9 Ankyrin repeats (many copies) Ank PF00023.30 KKK21432.1 - 1.5e-37 126.4 28.5 2.6e-05 24.4 0.4 13.2 13 0 0 13 13 12 9 Ankyrin repeat Ank_3 PF13606.6 KKK21432.1 - 2.3e-34 113.5 10.6 0.00025 21.2 0.3 13.0 13 0 0 13 13 13 6 Ankyrin repeat AAA_16 PF13191.6 KKK21432.1 - 7.7e-06 26.4 0.0 3.1e-05 24.4 0.0 2.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KKK21432.1 - 1.6e-05 25.2 0.0 7.7e-05 23.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KKK21432.1 - 5.7e-05 23.1 0.2 0.00022 21.2 0.2 2.0 1 1 0 1 1 1 1 NACHT domain NB-ARC PF00931.22 KKK21432.1 - 0.001 18.3 0.0 0.0034 16.6 0.0 1.8 2 0 0 2 2 2 1 NB-ARC domain AAA PF00004.29 KKK21432.1 - 0.0082 16.6 0.0 0.029 14.8 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rab3-GTPase_cat PF13890.6 KKK21432.1 - 0.053 13.2 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 Rab3 GTPase-activating protein catalytic subunit C1_2 PF03107.16 KKK21432.1 - 0.24 11.7 6.5 0.52 10.7 6.5 1.5 1 0 0 1 1 1 0 C1 domain CAP_N PF01213.19 KKK21432.1 - 0.34 10.4 3.0 0.78 9.2 3.0 1.5 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal ZZ PF00569.17 KKK21432.1 - 0.46 10.3 9.5 0.89 9.4 9.5 1.4 1 0 0 1 1 1 0 Zinc finger, ZZ type MFS_1 PF07690.16 KKK21434.1 - 1.3e-21 76.9 66.2 2.1e-18 66.4 46.1 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 KKK21435.1 - 1e-38 133.2 43.8 2.2e-36 125.6 30.8 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KKK21435.1 - 2.3e-11 43.3 13.3 2.8e-11 42.9 13.3 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter Trp_oprn_chp PF09534.10 KKK21435.1 - 0.028 14.2 0.4 0.028 14.2 0.4 1.8 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF2070 PF09843.9 KKK21435.1 - 0.52 8.5 9.4 0.98 7.6 9.4 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) NEMP PF10225.9 KKK21435.1 - 1.6 8.4 11.8 0.096 12.3 6.3 1.8 2 0 0 2 2 2 0 NEMP family Glyoxalase PF00903.25 KKK21436.1 - 7.5e-05 22.9 0.0 0.00025 21.2 0.0 1.7 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily ADH_N PF08240.12 KKK21437.1 - 8.7e-16 57.8 0.6 1.5e-15 57.0 0.6 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KKK21437.1 - 2.8e-13 50.0 0.2 1.9e-12 47.3 0.2 2.1 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KKK21437.1 - 1e-06 29.8 0.0 2e-06 28.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KKK21437.1 - 1.1e-05 25.0 0.0 0.019 14.4 0.0 2.3 2 0 0 2 2 2 2 Glucose dehydrogenase C-terminus UDPG_MGDP_dh_N PF03721.14 KKK21437.1 - 0.0033 17.0 0.0 0.0056 16.3 0.0 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain MTS PF05175.14 KKK21437.1 - 0.014 15.0 0.0 0.025 14.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain 2-Hacid_dh_C PF02826.19 KKK21437.1 - 0.017 14.5 0.0 0.029 13.7 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_25 PF13649.6 KKK21437.1 - 0.03 15.0 0.0 0.059 14.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Zn_clus PF00172.18 KKK21438.1 - 1.6e-06 28.1 7.0 3.9e-06 26.9 7.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain KAAG1 PF15354.6 KKK21438.1 - 0.035 14.6 0.0 0.29 11.7 0.0 2.6 2 0 0 2 2 2 0 Kidney-associated antigen 1 Methyltransf_2 PF00891.18 KKK21439.1 - 6.4e-17 61.5 0.0 1.1e-16 60.8 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_25 PF13649.6 KKK21439.1 - 0.0012 19.6 0.0 0.0026 18.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KKK21439.1 - 0.019 14.8 0.0 0.037 13.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 KKK21439.1 - 0.048 14.4 0.0 0.2 12.4 0.0 2.1 3 0 0 3 3 3 0 Methyltransferase domain Glyco_hydro_11 PF00457.17 KKK21441.1 - 7.1e-78 260.3 17.1 7.1e-78 260.3 17.1 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 11 CBM_1 PF00734.18 KKK21441.1 - 1.2e-11 44.3 12.9 1.2e-11 44.3 12.9 2.3 2 0 0 2 2 2 1 Fungal cellulose binding domain SOG2 PF10428.9 KKK21441.1 - 0.16 11.1 8.6 0.22 10.7 8.6 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein ADH_zinc_N PF00107.26 KKK21442.1 - 1.2e-10 41.5 0.2 2.3e-10 40.5 0.2 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KKK21442.1 - 9.3e-07 28.7 0.0 1.5e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain RmlD_sub_bind PF04321.17 KKK21442.1 - 0.0057 15.8 0.3 0.0093 15.1 0.3 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain DUF2888 PF11135.8 KKK21442.1 - 0.03 14.3 0.0 0.049 13.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2888) CutC PF03932.14 KKK21442.1 - 0.17 11.3 0.1 0.33 10.4 0.1 1.4 1 0 0 1 1 1 0 CutC family Gly_transf_sug PF04488.15 KKK21443.1 - 1.7e-13 51.0 0.1 2.9e-13 50.2 0.1 1.3 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.7 KKK21443.1 - 0.093 12.0 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain Cupin_3 PF05899.12 KKK21444.1 - 0.022 14.4 0.0 0.035 13.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF861) HpcH_HpaI PF03328.14 KKK21445.1 - 1.4e-33 115.9 0.0 1.6e-33 115.7 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PK PF00224.21 KKK21445.1 - 0.032 13.1 1.1 1.2 7.9 0.1 1.9 1 1 1 2 2 2 0 Pyruvate kinase, barrel domain AA_permease_2 PF13520.6 KKK21446.1 - 2.2e-45 155.2 51.0 2.9e-45 154.9 51.0 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KKK21446.1 - 2.5e-23 82.4 46.7 3.1e-23 82.1 46.7 1.0 1 0 0 1 1 1 1 Amino acid permease Nucleos_tra2_N PF01773.20 KKK21446.1 - 0.44 11.2 6.9 0.89 10.2 0.6 3.9 3 0 0 3 3 3 0 Na+ dependent nucleoside transporter N-terminus FAD_binding_4 PF01565.23 KKK21447.1 - 1.2e-24 86.7 3.5 1.9e-24 86.0 3.5 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KKK21447.1 - 5.9e-15 55.1 0.1 1.1e-14 54.3 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like PLRV_ORF5 PF01690.17 KKK21447.1 - 0.2 10.3 0.0 0.28 9.8 0.0 1.2 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Glycos_transf_1 PF00534.20 KKK21448.1 - 2.8e-08 33.5 0.0 6.9e-08 32.2 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KKK21448.1 - 0.002 18.6 0.0 0.0043 17.5 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 MFS_1 PF07690.16 KKK21449.1 - 3.4e-37 128.2 25.1 3.4e-37 128.2 25.1 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KKK21449.1 - 1.5e-14 53.8 7.0 1.5e-14 53.8 7.0 1.7 2 1 1 3 3 3 1 Sugar (and other) transporter FAD_binding_3 PF01494.19 KKK21450.1 - 4.1e-07 29.6 0.8 7.7e-06 25.4 0.2 2.7 2 1 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 KKK21450.1 - 0.00089 18.4 0.0 0.0017 17.5 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_9 PF13454.6 KKK21450.1 - 0.0012 18.9 0.0 0.0029 17.6 0.0 1.7 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 KKK21450.1 - 0.0049 16.2 0.0 0.007 15.6 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KKK21450.1 - 0.022 15.0 0.0 0.06 13.6 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 KKK21450.1 - 0.053 12.6 0.0 0.096 11.8 0.0 1.4 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.14 KKK21450.1 - 0.097 11.3 0.1 0.16 10.6 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein Thi4 PF01946.17 KKK21450.1 - 0.12 11.5 0.0 0.22 10.7 0.0 1.3 1 0 0 1 1 1 0 Thi4 family AD PF09793.9 KKK21451.1 - 2e-24 85.5 0.0 4.2e-24 84.5 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain TPT PF03151.16 KKK21451.1 - 1.6e-16 60.5 16.4 1.6e-16 60.5 16.4 1.6 2 0 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.20 KKK21451.1 - 1.8e-05 25.0 32.9 0.0091 16.2 16.6 2.6 2 0 0 2 2 2 2 EamA-like transporter family PUNUT PF16913.5 KKK21451.1 - 0.0044 16.3 17.6 0.0065 15.7 17.6 1.2 1 0 0 1 1 1 1 Purine nucleobase transmembrane transport REV PF00424.18 KKK21451.1 - 0.0073 16.3 0.4 0.016 15.2 0.4 1.6 1 0 0 1 1 1 1 REV protein (anti-repression trans-activator protein) PBP1_TM PF14812.6 KKK21451.1 - 3.7 8.0 15.4 9.1 6.7 4.6 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal AP_endonuc_2 PF01261.24 KKK21452.1 - 3.7e-29 101.7 0.1 1.4e-28 99.8 0.0 1.8 2 0 0 2 2 2 1 Xylose isomerase-like TIM barrel Mad3_BUB1_I PF08311.12 KKK21453.1 - 4.9e-44 149.3 0.0 1.1e-43 148.2 0.0 1.6 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Mad3_BUB1_II PF08171.11 KKK21453.1 - 5.9e-14 52.0 0.2 7.4e-13 48.5 0.0 2.7 3 0 0 3 3 3 1 Mad3/BUB1 homology region 2 Pkinase PF00069.25 KKK21453.1 - 3.2e-09 36.5 0.0 8.7e-09 35.1 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Mad3_BUB1_I_2 PF17014.5 KKK21453.1 - 0.0029 17.7 0.0 0.0071 16.5 0.0 1.7 1 0 0 1 1 1 1 Putative Mad3/BUB1 like region 1 protein Pkinase_Tyr PF07714.17 KKK21453.1 - 0.039 13.2 0.0 0.12 11.7 0.0 1.7 2 0 0 2 2 2 0 Protein tyrosine kinase Kinase-like PF14531.6 KKK21453.1 - 0.2 11.0 0.0 0.34 10.2 0.0 1.3 1 0 0 1 1 1 0 Kinase-like 6PGD PF00393.19 KKK21454.1 - 2.3e-128 427.6 0.0 2.9e-128 427.3 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 KKK21454.1 - 7.2e-51 172.5 0.0 1.1e-50 171.8 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 KKK21454.1 - 0.017 15.3 0.0 0.048 13.9 0.0 1.8 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase ANT PF03374.14 KKK21454.1 - 0.21 11.9 0.0 17 5.8 0.0 2.5 2 0 0 2 2 2 0 Phage antirepressor protein KilAC domain RRM_1 PF00076.22 KKK21455.1 - 1.6e-17 63.0 0.0 2.6e-17 62.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ABC2_membrane PF01061.24 KKK21456.1 - 8.6e-85 283.4 58.6 2.5e-47 161.0 24.8 3.3 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.27 KKK21456.1 - 6.7e-35 120.6 0.0 9.2e-17 61.8 0.0 2.6 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 KKK21456.1 - 3.1e-32 110.3 11.8 3.2e-28 97.5 0.0 3.3 3 0 0 3 3 2 2 CDR ABC transporter ABC2_membrane_3 PF12698.7 KKK21456.1 - 7.7e-12 45.0 42.4 2.1e-06 27.1 21.9 2.3 2 0 0 2 2 2 2 ABC-2 family transporter protein ABC_trans_N PF14510.6 KKK21456.1 - 6.7e-10 39.5 0.1 2.4e-09 37.6 0.1 2.1 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_21 PF13304.6 KKK21456.1 - 4.7e-08 33.2 0.0 0.0058 16.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KKK21456.1 - 2e-06 28.3 2.0 0.00018 22.0 0.1 3.1 2 1 1 3 3 3 1 AAA ATPase domain AAA_18 PF13238.6 KKK21456.1 - 5.2e-06 27.0 0.0 0.0015 19.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KKK21456.1 - 9.4e-06 25.9 0.8 0.01 16.1 0.1 3.7 3 1 0 3 3 2 1 AAA domain AAA_29 PF13555.6 KKK21456.1 - 1.1e-05 25.0 0.1 0.015 15.0 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KKK21456.1 - 2.1e-05 24.5 0.2 7.5e-05 22.7 0.0 1.8 2 0 0 2 2 2 1 RsgA GTPase AAA_33 PF13671.6 KKK21456.1 - 0.00011 22.3 0.0 0.0036 17.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 KKK21456.1 - 0.00014 22.4 0.4 0.0083 16.7 0.0 2.6 3 0 0 3 3 2 1 AAA domain cobW PF02492.19 KKK21456.1 - 0.00022 20.9 0.1 0.0041 16.7 0.0 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.23 KKK21456.1 - 0.00076 19.5 0.3 0.061 13.4 0.1 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_17 PF13207.6 KKK21456.1 - 0.0016 18.8 0.1 0.025 15.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KKK21456.1 - 0.0022 17.6 0.7 0.013 15.1 0.1 2.2 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KKK21456.1 - 0.0031 17.5 0.3 0.085 12.8 0.1 2.6 2 0 0 2 2 2 1 NACHT domain SMC_N PF02463.19 KKK21456.1 - 0.005 16.3 0.1 3.9 6.9 0.0 3.0 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 KKK21456.1 - 0.005 16.6 0.3 0.081 12.6 0.1 2.2 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 KKK21456.1 - 0.0064 16.7 0.1 0.0064 16.7 0.1 2.3 3 0 0 3 3 2 1 AAA domain dNK PF01712.19 KKK21456.1 - 0.016 15.1 0.0 0.035 14.0 0.0 1.5 1 0 0 1 1 1 0 Deoxynucleoside kinase AAA PF00004.29 KKK21456.1 - 0.022 15.2 0.0 0.76 10.2 0.0 2.9 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) FtsK_SpoIIIE PF01580.18 KKK21456.1 - 0.04 13.3 0.2 5.3 6.3 0.1 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family ABC_ATPase PF09818.9 KKK21456.1 - 0.058 12.2 0.9 0.28 9.9 0.5 2.2 3 0 0 3 3 3 0 Predicted ATPase of the ABC class RNA_helicase PF00910.22 KKK21456.1 - 0.15 12.4 0.1 4.1 7.9 0.0 2.6 2 0 0 2 2 2 0 RNA helicase DUF3600 PF12207.8 KKK21456.1 - 0.16 11.9 0.0 8.6 6.3 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3600) DnaB_C PF03796.15 KKK21456.1 - 0.16 11.3 0.1 2.8 7.2 0.0 2.2 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain Ploopntkinase3 PF18751.1 KKK21456.1 - 0.19 11.6 0.3 3.9 7.4 0.0 2.5 3 0 0 3 3 2 0 P-loop Nucleotide Kinase3 TsaE PF02367.17 KKK21456.1 - 0.22 11.6 1.3 0.35 10.9 0.4 1.7 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Dynamin_N PF00350.23 KKK21456.1 - 0.33 11.0 0.8 2.4 8.2 0.1 2.7 4 0 0 4 4 3 0 Dynamin family PBP1_TM PF14812.6 KKK21456.1 - 0.77 10.2 4.2 11 6.5 1.0 2.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF2024 PF09630.10 KKK21457.1 - 0.1 12.5 0.0 0.32 10.9 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF2024) zf-C2H2_4 PF13894.6 KKK21457.1 - 0.28 12.2 1.0 0.71 10.9 1.0 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger Helicase_C_3 PF13625.6 KKK21459.1 - 0.18 12.0 0.0 0.18 12.0 0.0 1.1 1 0 0 1 1 1 0 Helicase conserved C-terminal domain Citrate_synt PF00285.21 KKK21460.1 - 1.5e-91 307.2 0.0 1.8e-91 306.9 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain MmgE_PrpD PF03972.14 KKK21461.1 - 2.8e-186 619.3 6.5 1.1e-112 376.8 2.1 3.6 2 2 0 2 2 2 2 MmgE/PrpD family Sua5_yciO_yrdC PF01300.18 KKK21462.1 - 5e-14 52.2 0.0 7.2e-14 51.7 0.0 1.2 1 0 0 1 1 1 1 Telomere recombination RPA43_OB PF17875.1 KKK21462.1 - 0.14 12.8 0.4 2 9.0 1.0 2.0 2 0 0 2 2 2 0 RPA43 OB domain in RNA Pol I Abhydrolase_3 PF07859.13 KKK21465.1 - 3.4e-44 151.2 0.0 5.5e-44 150.6 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KKK21465.1 - 5.7e-09 35.4 0.3 1.5e-08 34.0 0.3 1.5 1 1 0 1 1 1 1 Carboxylesterase family AATase PF07247.12 KKK21466.1 - 4.9e-12 45.2 0.0 1.9e-06 26.7 0.0 2.8 2 1 1 3 3 3 2 Alcohol acetyltransferase AATase PF07247.12 KKK21467.1 - 1.7e-08 33.5 0.0 3e-08 32.7 0.0 1.4 1 1 0 1 1 1 1 Alcohol acetyltransferase WES_acyltransf PF03007.16 KKK21467.1 - 0.083 12.6 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Wax ester synthase-like Acyl-CoA acyltransferase domain Fungal_trans_2 PF11951.8 KKK21468.1 - 4.9e-06 25.6 0.0 7.1e-06 25.1 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DIT1_PvcA PF05141.12 KKK21469.1 - 8.2e-86 287.9 0.0 1.3e-85 287.2 0.0 1.3 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein AMP-binding PF00501.28 KKK21469.1 - 3.9e-25 88.3 0.0 6.5e-25 87.6 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Transferase PF02458.15 KKK21469.1 - 1.8e-07 30.2 0.0 0.00085 18.1 0.0 2.8 3 0 0 3 3 3 2 Transferase family PP-binding PF00550.25 KKK21469.1 - 5.4e-07 29.9 0.0 1.1e-06 28.8 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site MFS_1 PF07690.16 KKK21470.1 - 9.2e-07 28.1 31.9 1.6e-05 24.0 17.7 3.2 2 1 0 2 2 2 2 Major Facilitator Superfamily Spermine_synth PF01564.17 KKK21471.1 - 2.7e-69 232.3 0.0 1.2e-57 194.4 0.0 2.2 2 0 0 2 2 2 2 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 KKK21471.1 - 1.1e-23 82.8 0.1 1.8e-23 82.1 0.1 1.3 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Methyltransf_25 PF13649.6 KKK21471.1 - 9e-05 23.1 0.0 0.00021 21.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KKK21471.1 - 0.0014 19.3 0.1 0.021 15.5 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.7 KKK21471.1 - 0.02 14.8 0.0 0.035 14.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_24 PF13578.6 KKK21471.1 - 0.1 13.6 0.0 0.22 12.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Rep_fac-A_C PF08646.10 KKK21472.1 - 7.8e-42 142.5 0.5 1.2e-39 135.4 0.2 2.4 2 0 0 2 2 2 2 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 KKK21472.1 - 3.3e-37 126.3 0.1 3.5e-36 123.1 0.2 2.2 2 0 0 2 2 2 1 Replication protein A OB domain Rep-A_N PF04057.12 KKK21472.1 - 8e-22 77.2 0.0 2e-21 75.9 0.0 1.7 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.25 KKK21472.1 - 2.3e-13 49.9 0.0 5e-09 36.0 0.0 3.7 3 0 0 3 3 3 2 OB-fold nucleic acid binding domain CDC24_OB3 PF17244.2 KKK21472.1 - 0.039 13.7 1.0 0.21 11.3 0.2 2.4 3 0 0 3 3 3 0 Cell division control protein 24, OB domain 3 DUF223 PF02721.14 KKK21472.1 - 0.051 13.9 0.0 0.14 12.5 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function DUF223 zf-UBP_var PF17807.1 KKK21473.1 - 3.3e-26 90.8 2.2 3.1e-25 87.7 0.2 2.7 2 0 0 2 2 2 1 Variant UBP zinc finger UCH PF00443.29 KKK21473.1 - 8.6e-26 91.0 0.0 4.3e-15 55.9 0.0 2.4 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 KKK21473.1 - 7.5e-24 83.8 18.0 2.4e-20 72.6 1.6 3.8 3 2 0 3 3 3 2 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 KKK21473.1 - 1.5e-17 64.2 0.1 1.5e-15 57.6 0.0 3.3 3 1 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase UBA PF00627.31 KKK21473.1 - 5.6e-17 61.3 1.6 1.9e-09 37.2 0.1 2.9 3 0 0 3 3 3 2 UBA/TS-N domain UBA_4 PF14555.6 KKK21473.1 - 0.01 15.7 0.0 0.021 14.7 0.0 1.6 1 0 0 1 1 1 1 UBA-like domain TerY_C PF15616.6 KKK21473.1 - 0.38 10.9 6.6 1.4 9.0 0.1 3.2 3 1 0 3 3 3 0 TerY-C metal binding domain SH3_1 PF00018.28 KKK21485.1 - 1.7e-11 43.5 0.0 3.6e-11 42.5 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KKK21485.1 - 2.7e-09 36.7 0.1 5.5e-09 35.7 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KKK21485.1 - 2.1e-06 27.3 0.0 4e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain HMG-CoA_red PF00368.18 KKK21486.1 - 1.5e-137 458.5 8.1 2e-137 458.1 8.1 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase HPIH PF13323.6 KKK21486.1 - 1e-53 181.4 0.2 1.6e-53 180.7 0.2 1.3 1 0 0 1 1 1 1 N-terminal domain with HPIH motif Sterol-sensing PF12349.8 KKK21486.1 - 2.2e-13 50.3 3.5 6.1e-13 48.9 2.5 2.3 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 KKK21486.1 - 8.3e-08 30.8 4.5 1.5e-07 30.0 4.5 1.3 1 0 0 1 1 1 1 Patched family Acyl-CoA_dh_1 PF00441.24 KKK21487.1 - 1e-42 145.9 0.4 1.5e-42 145.4 0.4 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KKK21487.1 - 7.5e-22 77.3 0.1 1.3e-21 76.6 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Cyt-b5 PF00173.28 KKK21487.1 - 1.6e-19 69.8 0.3 3e-19 68.9 0.3 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_N PF02771.16 KKK21487.1 - 2.9e-19 69.8 0.0 5.8e-19 68.8 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 KKK21487.1 - 7.9e-10 39.1 0.0 1.3e-09 38.4 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Spt5-NGN PF03439.13 KKK21488.1 - 3.3e-25 87.8 0.0 5.8e-25 87.0 0.0 1.4 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section CTD PF12815.7 KKK21488.1 - 2.6e-16 59.9 24.3 3e-13 50.1 14.2 4.5 2 2 1 3 3 3 2 Spt5 C-terminal nonapeptide repeat binding Spt4 KOW PF00467.29 KKK21488.1 - 6.7e-13 48.1 9.8 0.00046 20.1 0.8 4.9 5 0 0 5 5 5 3 KOW motif DUF3912 PF13051.6 KKK21488.1 - 8.5e-06 26.0 1.0 0.0037 17.5 0.0 3.0 3 0 0 3 3 3 2 Protein of unknown function (DUF3912) RRM_1 PF00076.22 KKK21489.1 - 1.2e-15 57.1 0.0 1.7e-15 56.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ACPS PF01648.20 KKK21491.1 - 4.9e-11 42.8 0.0 1.2e-10 41.5 0.0 1.7 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily SNO PF01174.19 KKK21492.1 - 5.9e-53 179.5 0.0 6.3e-42 143.6 0.0 2.0 1 1 1 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.14 KKK21492.1 - 1.4e-07 31.4 0.0 2.9e-06 27.0 0.0 2.1 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.28 KKK21492.1 - 0.0068 16.2 0.0 0.019 14.8 0.0 1.6 1 1 0 1 1 1 1 Glutamine amidotransferase class-I DJ-1_PfpI PF01965.24 KKK21492.1 - 0.034 13.9 0.0 0.073 12.9 0.0 1.5 1 0 0 1 1 1 0 DJ-1/PfpI family Fapy_DNA_glyco PF01149.24 KKK21496.1 - 1.1e-34 119.5 0.0 4.1e-34 117.7 0.0 1.9 2 0 0 2 2 2 1 Formamidopyrimidine-DNA glycosylase N-terminal domain H2TH PF06831.14 KKK21496.1 - 2.1e-21 75.7 0.0 4.1e-21 74.8 0.0 1.4 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain YL1 PF05764.13 KKK21496.1 - 0.00028 21.1 6.2 0.00036 20.7 6.2 1.2 1 0 0 1 1 1 1 YL1 nuclear protein FbpA PF05833.11 KKK21496.1 - 0.012 14.4 0.2 0.022 13.5 0.2 1.5 1 1 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) Ribosomal_S13 PF00416.22 KKK21496.1 - 0.031 14.7 0.0 0.056 13.8 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein S13/S18 Cid2 PF09774.9 KKK21497.1 - 4.3e-56 189.8 0.2 5e-56 189.6 0.2 1.0 1 0 0 1 1 1 1 Caffeine-induced death protein 2 AIRC PF00731.20 KKK21498.1 - 1.4e-58 196.7 2.5 2.9e-58 195.6 2.5 1.6 1 0 0 1 1 1 1 AIR carboxylase ATP-grasp PF02222.22 KKK21498.1 - 7e-52 175.5 0.1 2.3e-51 173.8 0.0 1.8 2 0 0 2 2 2 1 ATP-grasp domain PurK_C PF17769.1 KKK21498.1 - 2.8e-18 65.3 0.6 8.3e-18 63.8 0.2 2.1 2 0 0 2 2 2 1 Phosphoribosylaminoimidazole carboxylase C-terminal domain CPSase_L_D2 PF02786.17 KKK21498.1 - 1.5e-06 27.9 0.0 3.8e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain AlaDh_PNT_C PF01262.21 KKK21498.1 - 1.9e-06 27.4 0.1 4.4e-06 26.1 0.1 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Dala_Dala_lig_C PF07478.13 KKK21498.1 - 0.00026 20.6 0.0 0.0024 17.4 0.0 2.2 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus 2-Hacid_dh_C PF02826.19 KKK21498.1 - 0.0059 16.0 0.0 0.012 15.0 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PrpR_N PF06506.11 KKK21498.1 - 0.012 15.1 0.4 0.18 11.4 0.1 2.5 2 0 0 2 2 2 0 Propionate catabolism activator NAD_binding_2 PF03446.15 KKK21498.1 - 0.015 15.4 0.0 0.04 14.1 0.0 1.8 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 KKK21498.1 - 0.018 15.0 0.2 0.048 13.5 0.2 1.8 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ATP-grasp_5 PF13549.6 KKK21498.1 - 0.026 14.0 0.0 0.055 12.9 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain XdhC_C PF13478.6 KKK21498.1 - 0.029 14.9 0.1 0.22 12.0 0.1 2.3 1 1 1 2 2 2 0 XdhC Rossmann domain Peptidase_M15_3 PF08291.11 KKK21498.1 - 0.033 14.3 0.0 40 4.3 0.0 3.8 3 1 0 3 3 3 0 Peptidase M15 ATP-grasp_3 PF02655.14 KKK21498.1 - 0.052 13.6 0.0 0.2 11.7 0.0 1.9 2 0 0 2 2 2 0 ATP-grasp domain PPP4R2 PF09184.11 KKK21499.1 - 5.3e-10 39.4 1.1 7e-09 35.7 0.8 2.2 1 1 0 1 1 1 1 PPP4R2 PCI PF01399.27 KKK21500.1 - 0.0051 17.3 0.0 0.0085 16.6 0.0 1.3 1 0 0 1 1 1 1 PCI domain CSN7a_helixI PF18392.1 KKK21500.1 - 0.0084 16.0 0.4 0.016 15.1 0.0 1.5 2 0 0 2 2 2 1 COP9 signalosome complex subunit 7a helix I domain FMN_dh PF01070.18 KKK21501.1 - 2e-123 411.9 1.3 2.3e-123 411.7 1.3 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 KKK21501.1 - 9.2e-10 38.0 4.5 6.2e-09 35.3 2.5 2.5 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 KKK21501.1 - 1.1e-07 31.4 1.7 2e-05 23.9 0.4 3.0 2 1 1 3 3 3 1 Conserved region in glutamate synthase NMO PF03060.15 KKK21501.1 - 7.8e-07 28.8 0.7 1.2e-06 28.1 0.7 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase ThiG PF05690.14 KKK21501.1 - 4.4e-06 26.2 3.3 0.012 14.9 0.2 3.2 2 1 1 3 3 3 2 Thiazole biosynthesis protein ThiG DHO_dh PF01180.21 KKK21501.1 - 0.00012 21.4 2.2 0.0029 16.9 0.1 2.2 1 1 1 2 2 2 1 Dihydroorotate dehydrogenase His_biosynth PF00977.21 KKK21501.1 - 0.00023 20.7 0.7 0.0012 18.3 0.2 2.3 2 1 1 3 3 3 1 Histidine biosynthesis protein Dus PF01207.17 KKK21501.1 - 0.00025 20.3 0.3 0.016 14.4 0.2 2.2 2 0 0 2 2 2 1 Dihydrouridine synthase (Dus) G3P_antiterm PF04309.12 KKK21501.1 - 0.0078 15.6 0.4 3.8 6.9 0.0 2.9 3 0 0 3 3 3 2 Glycerol-3-phosphate responsive antiterminator PA PF02225.22 KKK21501.1 - 0.035 14.1 0.2 15 5.7 0.0 2.5 2 1 0 2 2 2 0 PA domain PcrB PF01884.17 KKK21501.1 - 0.048 13.1 1.8 1.3 8.4 0.2 2.6 1 1 1 2 2 2 0 PcrB family ApbA_C PF08546.11 KKK21502.1 - 1.5e-29 102.7 0.0 3e-29 101.8 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 KKK21502.1 - 1.5e-25 89.6 0.1 2.2e-25 89.1 0.1 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA CelTOS PF18659.1 KKK21502.1 - 0.064 13.7 0.0 0.19 12.1 0.0 1.7 2 0 0 2 2 2 0 Cell-traversal protein for ookinetes and sporozoites AlaDh_PNT_C PF01262.21 KKK21502.1 - 0.097 12.0 0.2 0.17 11.2 0.2 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain PglD_N PF17836.1 KKK21502.1 - 0.13 12.9 0.4 0.31 11.7 0.1 1.8 2 0 0 2 2 2 0 PglD N-terminal domain RGS PF00615.19 KKK21503.1 - 1.1e-11 45.0 0.0 1.8e-08 34.7 0.0 2.3 2 0 0 2 2 2 2 Regulator of G protein signaling domain NMN_transporter PF04973.12 KKK21503.1 - 0.17 11.8 3.3 0.31 11.0 3.3 1.4 1 0 0 1 1 1 0 Nicotinamide mononucleotide transporter Ribonuc_L-PSP PF01042.21 KKK21504.1 - 4.6e-33 113.8 0.0 5.4e-33 113.6 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP DUF2263 PF10021.9 KKK21505.1 - 1.9e-23 83.5 0.0 3e-23 82.8 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) Macro PF01661.21 KKK21505.1 - 0.045 13.8 0.0 0.12 12.4 0.0 1.7 2 0 0 2 2 2 0 Macro domain NARP1 PF12569.8 KKK21506.1 - 6.2e-219 728.2 25.0 8.9e-217 721.1 16.2 2.5 3 0 0 3 3 3 2 NMDA receptor-regulated protein 1 TPR_19 PF14559.6 KKK21506.1 - 1.5e-15 57.4 31.5 0.0094 16.4 1.1 7.8 8 0 0 8 8 7 6 Tetratricopeptide repeat TPR_14 PF13428.6 KKK21506.1 - 6.3e-15 54.6 27.3 0.01 16.6 0.3 11.2 9 3 4 13 13 10 5 Tetratricopeptide repeat TPR_2 PF07719.17 KKK21506.1 - 1.2e-14 53.2 45.5 0.00022 21.1 0.5 11.7 14 0 0 14 14 11 5 Tetratricopeptide repeat TPR_16 PF13432.6 KKK21506.1 - 7.6e-13 48.9 29.3 0.0099 16.5 0.8 10.0 9 1 2 11 11 11 3 Tetratricopeptide repeat ANAPC3 PF12895.7 KKK21506.1 - 2.4e-09 37.3 19.5 5.2e-07 29.8 2.3 5.6 4 1 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 KKK21506.1 - 1.8e-07 30.7 25.9 0.00023 20.8 0.2 7.7 9 0 0 9 9 8 2 TPR repeat TPR_12 PF13424.6 KKK21506.1 - 2.8e-07 30.7 27.2 0.23 11.8 0.1 9.0 9 1 0 9 9 8 2 Tetratricopeptide repeat TPR_9 PF13371.6 KKK21506.1 - 4.9e-07 29.8 11.9 0.032 14.4 2.9 6.0 5 2 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 KKK21506.1 - 1e-06 28.7 14.7 0.14 12.6 0.0 7.3 8 0 0 8 8 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 KKK21506.1 - 2.9e-05 23.9 38.3 0.00099 19.2 0.2 9.3 11 0 0 11 11 8 2 Tetratricopeptide repeat TPR_1 PF00515.28 KKK21506.1 - 5.1e-05 22.9 37.9 5.3e-05 22.9 0.4 9.7 12 0 0 12 12 11 1 Tetratricopeptide repeat TPR_MalT PF17874.1 KKK21506.1 - 0.00031 20.2 8.3 0.54 9.6 1.3 3.6 2 1 1 3 3 3 2 MalT-like TPR region Rapsyn_N PF10579.9 KKK21506.1 - 0.0024 17.9 3.1 0.32 11.1 0.1 4.1 2 1 1 3 3 3 1 Rapsyn N-terminal myristoylation and linker region DUF4290 PF14123.6 KKK21506.1 - 0.01 15.4 1.1 0.026 14.1 1.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4290) TPR_6 PF13174.6 KKK21506.1 - 0.011 16.4 23.8 0.7 10.7 0.2 9.0 10 0 0 10 10 9 0 Tetratricopeptide repeat BTAD PF03704.17 KKK21506.1 - 0.016 15.7 0.2 0.016 15.7 0.2 4.2 5 0 0 5 5 4 0 Bacterial transcriptional activator domain TPR_4 PF07721.14 KKK21506.1 - 0.054 14.1 4.3 0.41 11.4 0.1 4.3 5 0 0 5 5 2 0 Tetratricopeptide repeat TPR_3 PF07720.12 KKK21506.1 - 0.21 11.6 3.7 2.2 8.3 0.2 3.8 3 0 0 3 3 2 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KKK21506.1 - 1.3 9.1 13.6 13 6.0 0.1 5.7 7 1 0 7 7 6 0 Fis1 C-terminal tetratricopeptide repeat TPR_7 PF13176.6 KKK21506.1 - 2 8.6 14.6 15 5.9 0.0 6.7 9 0 0 9 9 6 0 Tetratricopeptide repeat L31 PF09784.9 KKK21506.1 - 2.5 8.6 5.4 0.92 10.0 1.8 2.1 2 0 0 2 2 1 0 Mitochondrial ribosomal protein L31 TPR_10 PF13374.6 KKK21506.1 - 4.5 7.3 21.8 4.5 7.3 0.0 6.6 7 0 0 7 7 6 0 Tetratricopeptide repeat DUF4449 PF14613.6 KKK21507.1 - 3.5e-61 206.1 11.3 7e-61 205.1 0.1 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF4449) HMA PF00403.26 KKK21508.1 - 1.3e-49 166.5 1.6 4.8e-13 49.3 0.1 4.6 4 0 0 4 4 4 4 Heavy-metal-associated domain E1-E2_ATPase PF00122.20 KKK21508.1 - 3.3e-47 160.3 0.7 3.3e-47 160.3 0.7 2.7 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 KKK21508.1 - 2e-36 126.3 0.1 3.7e-36 125.4 0.1 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase B12-binding PF02310.19 KKK21508.1 - 0.0013 18.7 0.0 3 7.9 0.0 4.2 4 1 1 5 5 5 1 B12 binding domain Hydrolase_3 PF08282.12 KKK21508.1 - 0.0014 18.5 1.2 0.0029 17.4 0.1 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Bromodomain PF00439.25 KKK21509.1 - 5.9e-23 80.8 1.0 1.3e-22 79.7 1.0 1.5 1 0 0 1 1 1 1 Bromodomain Acetyltransf_1 PF00583.25 KKK21509.1 - 2.1e-08 34.4 0.0 4.6e-08 33.3 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KKK21509.1 - 2.2e-07 30.8 0.3 1.4e-06 28.3 0.1 2.1 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KKK21509.1 - 0.00016 22.0 0.3 0.0005 20.4 0.1 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Rad1 PF02144.16 KKK21510.1 - 6.1e-93 310.9 0.2 7e-93 310.7 0.2 1.0 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Ost5 PF05251.12 KKK21511.1 - 1.4e-19 70.1 11.5 1.6e-19 69.9 11.5 1.1 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit 5 DUF485 PF04341.12 KKK21511.1 - 0.08 12.9 2.4 0.091 12.7 2.4 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF485 CRAL_TRIO_N PF03765.15 KKK21513.1 - 1.6e-09 37.8 0.6 2.6e-09 37.1 0.0 1.7 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain IPP-2 PF04979.14 KKK21514.1 - 6.1e-20 72.3 18.4 6.1e-20 72.3 18.4 2.4 2 1 0 2 2 2 1 Protein phosphatase inhibitor 2 (IPP-2) DLH PF01738.18 KKK21516.1 - 4e-14 52.7 0.0 9.8e-14 51.4 0.0 1.6 1 1 0 1 1 1 1 Dienelactone hydrolase family ketoacyl-synt PF00109.26 KKK21517.1 - 3.4e-74 249.6 0.0 6.5e-74 248.7 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 KKK21517.1 - 8.4e-52 175.7 0.0 2.7e-51 174.0 0.0 2.0 1 0 0 1 1 1 1 KR domain PS-DH PF14765.6 KKK21517.1 - 1.4e-47 162.4 0.0 2.7e-47 161.4 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 KKK21517.1 - 1.2e-39 136.7 0.1 2.2e-39 135.9 0.1 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KKK21517.1 - 8.2e-27 93.6 0.0 2.3e-26 92.1 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.12 KKK21517.1 - 6.6e-19 68.5 0.0 2.5e-18 66.6 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 KKK21517.1 - 1.4e-18 67.4 0.0 7.2e-18 65.1 0.0 2.2 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension Methyltransf_25 PF13649.6 KKK21517.1 - 1.9e-12 47.7 0.0 1.2e-11 45.2 0.0 2.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KKK21517.1 - 1.9e-11 44.0 0.0 5.2e-11 42.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KKK21517.1 - 1e-10 42.1 0.0 2.9e-10 40.7 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KKK21517.1 - 1.7e-10 41.0 0.0 3.8e-10 39.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.25 KKK21517.1 - 2.3e-10 40.2 0.5 1.7e-09 37.4 0.0 2.5 3 0 0 3 3 3 1 short chain dehydrogenase PP-binding PF00550.25 KKK21517.1 - 1.1e-08 35.3 0.1 4.4e-08 33.4 0.1 2.1 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.23 KKK21517.1 - 3.7e-05 23.2 0.1 7.3e-05 22.2 0.1 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Ubie_methyltran PF01209.18 KKK21517.1 - 0.00021 20.7 0.0 0.0004 19.8 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family adh_short_C2 PF13561.6 KKK21517.1 - 0.00042 19.9 0.0 0.001 18.7 0.0 1.6 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Methyltransf_16 PF10294.9 KKK21517.1 - 0.0084 15.9 0.0 0.018 14.8 0.0 1.4 1 0 0 1 1 1 1 Lysine methyltransferase DUF938 PF06080.12 KKK21517.1 - 0.016 14.9 0.0 0.042 13.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF938) DREV PF05219.12 KKK21517.1 - 0.096 11.8 0.0 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_33 PF10017.9 KKK21517.1 - 0.096 11.8 0.0 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent GDP_Man_Dehyd PF16363.5 KKK21517.1 - 0.12 11.7 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Mab-21 PF03281.14 KKK21519.1 - 0.062 12.6 0.1 0.094 12.0 0.1 1.2 1 0 0 1 1 1 0 Mab-21 protein Bac_rhamnosid6H PF17389.2 KKK21520.1 - 7.9e-126 419.9 0.0 1.1e-125 419.4 0.0 1.2 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid_N PF08531.10 KKK21520.1 - 1.1e-55 188.1 0.0 2e-55 187.3 0.0 1.5 1 0 0 1 1 1 1 Alpha-L-rhamnosidase N-terminal domain Bac_rhamnosid_C PF17390.2 KKK21520.1 - 5.8e-24 83.7 0.1 1.2e-23 82.6 0.1 1.6 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase C-terminal domain Bac_rhamnosid PF05592.11 KKK21520.1 - 1.4e-23 82.8 0.0 3.2e-23 81.6 0.0 1.6 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase concanavalin-like domain Glyco_hydro_30 PF02055.16 KKK21521.1 - 1.1e-33 116.7 2.2 1.7e-33 116.0 2.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Glyco_hydro_30C PF17189.4 KKK21521.1 - 5e-09 36.2 0.2 1.2e-08 35.1 0.2 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 beta sandwich domain Glyco_hydro_59 PF02057.15 KKK21521.1 - 0.0001 21.7 0.9 0.00031 20.1 0.9 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 59 PvlArgDC PF01862.16 KKK21521.1 - 0.094 12.5 0.1 7.3 6.4 0.0 2.4 2 0 0 2 2 2 0 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) Peptidase_M75 PF09375.10 KKK21521.1 - 0.3 10.5 1.7 0.56 9.6 0.6 1.9 3 0 0 3 3 3 0 Imelysin Glyco_hydro_16 PF00722.21 KKK21522.1 - 4.9e-42 143.4 4.0 8.2e-42 142.7 4.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Nop16 PF09420.10 KKK21538.1 - 1e-69 234.8 11.3 1.1e-69 234.6 11.3 1.0 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 Myb_DNA-binding PF00249.31 KKK21538.1 - 0.071 13.3 0.1 0.12 12.5 0.1 1.4 1 0 0 1 1 1 0 Myb-like DNA-binding domain Coilin_N PF15862.5 KKK21538.1 - 4.6 7.1 7.4 0.14 11.9 1.1 1.6 2 0 0 2 2 2 0 Coilin N-terminus Zip PF02535.22 KKK21539.1 - 2.5e-62 211.1 5.3 5.6e-62 209.9 5.3 1.5 1 1 0 1 1 1 1 ZIP Zinc transporter Anp1 PF03452.14 KKK21541.1 - 2.5e-107 358.2 0.0 3e-107 358.0 0.0 1.0 1 0 0 1 1 1 1 Anp1 Glycos_transf_2 PF00535.26 KKK21541.1 - 0.0092 15.8 0.0 0.017 15.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Mito_carr PF00153.27 KKK21542.1 - 5.5e-55 183.3 0.4 3.9e-19 68.4 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Aldedh PF00171.22 KKK21543.1 - 1.2e-171 571.3 1.1 7.4e-171 568.7 1.1 1.8 1 1 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 KKK21543.1 - 0.17 11.3 0.0 0.48 9.8 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) SGL PF08450.12 KKK21544.1 - 7.6e-81 271.3 0.0 9.5e-81 271.0 0.0 1.1 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Kelch_4 PF13418.6 KKK21546.1 - 8.8e-17 60.8 1.6 4.4e-07 29.8 0.0 5.3 4 1 0 4 4 4 2 Galactose oxidase, central domain Kelch_5 PF13854.6 KKK21546.1 - 9.9e-16 57.3 0.2 2.5e-05 24.2 0.0 4.5 3 1 0 3 3 3 3 Kelch motif Kelch_3 PF13415.6 KKK21546.1 - 5.8e-13 48.8 3.5 1e-06 28.9 0.0 5.8 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_1 PF01344.25 KKK21546.1 - 3.8e-12 45.6 0.0 0.0049 16.4 0.0 4.4 3 1 0 3 3 3 3 Kelch motif Kelch_2 PF07646.15 KKK21546.1 - 2.6e-10 39.8 2.2 0.002 18.1 0.0 4.6 3 1 0 3 3 3 3 Kelch motif Kelch_6 PF13964.6 KKK21546.1 - 8.6e-10 38.5 8.5 0.028 14.7 0.7 5.8 4 1 1 5 5 5 3 Kelch motif WD40 PF00400.32 KKK21547.1 - 1.9e-13 50.6 7.8 4.2e-05 24.2 0.0 5.3 5 0 0 5 5 5 3 WD domain, G-beta repeat DUF4831 PF16115.5 KKK21547.1 - 0.24 10.4 0.0 2.4 7.1 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4831) CTP_transf_like PF01467.26 KKK21548.1 - 1.3e-05 25.4 0.1 0.00048 20.4 0.1 2.9 2 1 0 2 2 2 1 Cytidylyltransferase-like AhpC-TSA PF00578.21 KKK21549.1 - 8e-34 116.2 0.0 1.5e-33 115.3 0.0 1.4 1 1 1 2 2 2 1 AhpC/TSA family 1-cysPrx_C PF10417.9 KKK21549.1 - 2.2e-16 59.4 0.2 3.6e-16 58.7 0.2 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Redoxin PF08534.10 KKK21549.1 - 5.5e-13 48.9 0.0 7.2e-13 48.5 0.0 1.1 1 0 0 1 1 1 1 Redoxin EVE PF01878.18 KKK21550.1 - 5.8e-46 156.1 0.0 1.6e-44 151.4 0.0 2.2 1 1 0 1 1 1 1 EVE domain AT_hook PF02178.19 KKK21550.1 - 0.0028 17.4 14.5 0.15 12.0 6.0 3.1 2 0 0 2 2 2 2 AT hook motif Acyl_transf_3 PF01757.22 KKK21551.1 - 2.5e-32 112.3 36.9 4.2e-32 111.5 36.9 1.4 1 1 0 1 1 1 1 Acyltransferase family UPF0182 PF03699.13 KKK21551.1 - 0.0088 14.2 0.5 0.016 13.4 0.5 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0182) mRNA_triPase PF02940.15 KKK21552.1 - 4.3e-58 196.6 0.0 8.3e-58 195.7 0.0 1.5 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain PepSY PF03413.19 KKK21552.1 - 0.14 12.8 0.0 1.8 9.2 0.0 2.3 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain BCS1_N PF08740.11 KKK21553.1 - 1.9e-48 164.9 0.6 2.6e-48 164.5 0.6 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 KKK21553.1 - 2e-18 67.1 0.0 3.5e-18 66.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KKK21553.1 - 9.3e-05 22.9 0.0 0.00026 21.4 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain DUF815 PF05673.13 KKK21553.1 - 0.00045 19.5 0.0 0.00072 18.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_21 PF13304.6 KKK21553.1 - 0.0024 17.7 0.0 0.0044 16.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_7 PF12775.7 KKK21553.1 - 0.0029 17.1 0.0 0.0066 16.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_5 PF07728.14 KKK21553.1 - 0.0093 16.0 0.0 0.028 14.4 0.0 1.9 1 1 1 2 2 2 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 KKK21553.1 - 0.012 16.2 0.0 0.023 15.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KKK21553.1 - 0.013 15.3 0.0 0.063 13.0 0.0 2.0 1 1 1 2 2 2 0 AAA domain RNA_helicase PF00910.22 KKK21553.1 - 0.015 15.7 0.0 0.041 14.3 0.0 1.8 2 0 0 2 2 1 0 RNA helicase AAA_25 PF13481.6 KKK21553.1 - 0.019 14.6 0.0 0.091 12.3 0.0 2.0 1 1 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KKK21553.1 - 0.019 15.5 0.0 0.044 14.3 0.0 1.6 1 0 0 1 1 1 0 ABC transporter PPV_E1_C PF00519.17 KKK21553.1 - 0.02 13.8 0.0 0.029 13.2 0.0 1.2 1 0 0 1 1 1 0 Papillomavirus helicase AAA_22 PF13401.6 KKK21553.1 - 0.035 14.4 0.0 0.11 12.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KKK21553.1 - 0.037 14.2 0.0 0.11 12.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 KKK21553.1 - 0.041 13.6 0.0 0.1 12.3 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATPase PF06745.13 KKK21553.1 - 0.052 12.9 0.0 0.11 11.8 0.0 1.5 1 0 0 1 1 1 0 KaiC RsgA_GTPase PF03193.16 KKK21553.1 - 0.066 13.1 0.0 0.39 10.6 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase MMR_HSR1 PF01926.23 KKK21553.1 - 0.092 12.8 0.0 0.22 11.6 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase RuvB_N PF05496.12 KKK21553.1 - 0.11 12.2 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Rad17 PF03215.15 KKK21553.1 - 0.13 12.2 0.0 0.31 10.9 0.0 1.6 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_11 PF13086.6 KKK21553.1 - 0.18 11.6 0.0 0.31 10.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain Lactamase_B_2 PF12706.7 KKK21555.1 - 1e-32 113.3 0.0 8.2e-32 110.3 0.0 2.0 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KKK21555.1 - 2.5e-12 47.0 0.0 2.2e-11 43.9 0.0 2.3 2 1 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KKK21555.1 - 5.3e-06 26.6 0.3 0.0025 17.8 0.1 2.6 2 1 0 2 2 2 2 Metallo-beta-lactamase superfamily PALP PF00291.25 KKK21562.1 - 2.1e-65 221.0 0.1 2.6e-65 220.8 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Pkinase PF00069.25 KKK21563.1 - 0.029 13.8 0.0 0.04 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain Pkinase PF00069.25 KKK21564.1 - 2.3e-70 237.0 0.0 3.1e-70 236.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK21564.1 - 3.6e-48 164.1 0.0 5.3e-48 163.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KKK21564.1 - 5.6e-05 22.1 0.0 0.00011 21.1 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KKK21564.1 - 0.00034 20.0 0.0 0.0021 17.5 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 KKK21564.1 - 0.014 14.4 0.0 0.021 13.8 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain ABC1 PF03109.16 KKK21564.1 - 0.078 13.1 0.0 0.22 11.7 0.0 1.7 1 0 0 1 1 1 0 ABC1 family FAD-oxidase_C PF02913.19 KKK21565.1 - 2.6e-61 207.4 0.0 3.5e-61 207.0 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 KKK21565.1 - 3.7e-37 127.1 0.5 6.5e-37 126.4 0.5 1.4 1 0 0 1 1 1 1 FAD binding domain Pkinase PF00069.25 KKK21566.1 - 1.8e-23 83.3 0.0 2.2e-23 83.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK21566.1 - 1.2e-05 24.8 0.0 2.4e-05 23.8 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KKK21566.1 - 0.021 13.6 0.0 0.028 13.2 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Oxidored_molyb PF00174.19 KKK21567.1 - 8.6e-57 191.5 0.0 1.3e-56 190.9 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 KKK21567.1 - 7e-26 90.9 1.7 1.4e-25 89.9 1.7 1.4 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain NinD PF17466.2 KKK21567.1 - 0.027 14.5 0.1 0.094 12.8 0.1 1.9 1 0 0 1 1 1 0 Family of unknown function DUF4048 PF13257.6 KKK21568.1 - 1.6e-70 237.8 18.3 1.6e-70 237.8 18.3 3.7 4 0 0 4 4 4 1 Domain of unknown function (DUF4048) Bap31_Bap29_C PF18035.1 KKK21568.1 - 0.045 13.8 0.9 0.1 12.6 0.9 1.6 1 0 0 1 1 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain GrpE PF01025.19 KKK21568.1 - 0.062 13.0 0.5 0.11 12.2 0.5 1.3 1 0 0 1 1 1 0 GrpE SKA1 PF07160.12 KKK21568.1 - 2.7 7.8 6.3 24 4.6 2.0 3.0 3 0 0 3 3 3 0 Spindle and kinetochore-associated protein 1 Tim17 PF02466.19 KKK21569.1 - 1.5e-40 138.0 6.2 1.5e-40 138.0 6.2 1.8 2 0 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family Methyltransf_16 PF10294.9 KKK21570.1 - 0.0017 18.1 0.0 0.26 11.0 0.0 2.8 3 0 0 3 3 3 2 Lysine methyltransferase M20_dimer PF07687.14 KKK21575.1 - 1.8e-12 47.1 0.0 2.5e-12 46.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase dimerisation domain Antimicrobial_1 PF08018.11 KKK21575.1 - 0.44 10.7 1.5 1 9.6 1.5 1.6 1 0 0 1 1 1 0 Frog antimicrobial peptide RRM_1 PF00076.22 KKK21576.1 - 8.6e-46 153.6 0.0 7.8e-17 60.9 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KKK21576.1 - 7.7e-06 25.8 0.1 0.0016 18.4 0.0 3.0 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 KKK21576.1 - 0.00014 21.9 0.0 0.0012 18.8 0.0 2.3 3 0 0 3 3 3 1 RNA binding motif RRM_occluded PF16842.5 KKK21576.1 - 0.0002 21.2 0.0 0.059 13.2 0.0 2.7 3 0 0 3 3 3 1 Occluded RNA-recognition motif RRM_7 PF16367.5 KKK21576.1 - 0.00053 20.0 0.1 0.052 13.7 0.0 2.9 3 1 0 3 3 3 1 RNA recognition motif RRM_5 PF13893.6 KKK21576.1 - 0.0088 15.6 0.0 0.06 12.9 0.0 2.2 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 KKK21576.1 - 0.088 13.0 0.1 14 5.8 0.0 3.6 3 1 1 4 4 4 0 Cytosolic domain of 10TM putative phosphate transporter LRR_4 PF12799.7 KKK21577.1 - 0.022 15.2 5.6 6.2 7.4 0.1 5.4 2 1 4 6 6 6 0 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KKK21577.1 - 0.094 12.8 3.6 1.6e+02 2.7 0.0 6.3 8 0 0 8 8 8 0 Leucine Rich repeat CDC45 PF02724.14 KKK21577.1 - 0.53 8.5 4.0 0.8 7.9 4.0 1.2 1 0 0 1 1 1 0 CDC45-like protein G-alpha PF00503.20 KKK21578.1 - 2.7e-113 378.7 0.1 3.1e-113 378.5 0.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KKK21578.1 - 6.4e-15 55.0 0.2 5.4e-10 39.0 0.0 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KKK21578.1 - 0.00019 20.9 0.1 0.33 10.3 0.0 2.2 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 KKK21578.1 - 0.0089 16.2 0.2 1 9.6 0.1 2.4 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 KKK21578.1 - 0.11 12.2 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Phosphorylase PF00343.20 KKK21579.1 - 0 1055.9 0.0 0 1055.7 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase zf-C2HC_2 PF13913.6 KKK21579.1 - 0.35 10.8 1.8 23 5.0 0.1 2.6 2 0 0 2 2 2 0 zinc-finger of a C2HC-type ABC_membrane_2 PF06472.15 KKK21580.1 - 6.2e-106 353.7 0.6 1.1e-105 352.8 0.6 1.4 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 KKK21580.1 - 2.1e-17 63.9 0.0 4e-17 63.0 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KKK21580.1 - 8.2e-05 22.5 0.0 0.00026 20.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KKK21580.1 - 0.0056 17.2 0.0 0.011 16.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 KKK21580.1 - 0.014 15.1 0.0 0.037 13.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Glyco_transf_22 PF03901.17 KKK21580.1 - 0.043 13.0 0.0 0.07 12.3 0.0 1.3 1 0 0 1 1 1 0 Alg9-like mannosyltransferase family SMC_N PF02463.19 KKK21580.1 - 0.051 13.0 0.0 0.13 11.7 0.0 1.6 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain RuvB_N PF05496.12 KKK21580.1 - 0.054 13.2 0.1 1.5 8.5 0.0 2.7 3 0 0 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain Rad17 PF03215.15 KKK21580.1 - 0.12 12.3 0.0 0.3 11.0 0.0 1.6 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_27 PF13514.6 KKK21580.1 - 0.12 11.9 0.0 0.3 10.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KKK21580.1 - 0.17 12.2 0.4 0.96 9.8 0.1 2.3 2 0 0 2 2 2 0 AAA ATPase domain HEAT_2 PF13646.6 KKK21581.1 - 1.1e-09 38.5 1.4 0.018 15.4 0.0 6.0 5 1 1 6 6 6 4 HEAT repeats HEAT PF02985.22 KKK21581.1 - 9.7e-05 22.3 13.7 0.075 13.3 0.0 8.8 11 0 0 11 11 11 2 HEAT repeat Cnd1 PF12717.7 KKK21581.1 - 0.0025 17.9 0.2 16 5.5 0.0 4.9 4 0 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 KKK21581.1 - 0.005 16.4 2.2 3.3 7.2 0.0 4.7 4 0 0 4 4 4 1 CLASP N terminal HEAT_EZ PF13513.6 KKK21581.1 - 0.04 14.5 10.1 10 6.8 0.0 6.9 7 0 0 7 7 7 0 HEAT-like repeat Vac14_Fab1_bd PF12755.7 KKK21581.1 - 0.045 14.3 0.0 20 5.9 0.0 4.2 4 0 0 4 4 4 0 Vacuolar 14 Fab1-binding region RTP1_C1 PF10363.9 KKK21581.1 - 0.14 12.3 1.5 75 3.6 0.0 5.2 7 0 0 7 7 7 0 Required for nuclear transport of RNA pol II C-terminus 1 Transcrip_reg PF01709.20 KKK21582.1 - 3e-69 233.1 1.8 3.5e-69 232.9 1.8 1.0 1 0 0 1 1 1 1 Transcriptional regulator CENP-I PF07778.11 KKK21583.1 - 7e-41 140.5 0.1 3.2e-40 138.3 0.1 1.8 1 1 0 1 1 1 1 Mis6 FANCF PF11107.8 KKK21583.1 - 0.055 12.7 0.0 1.2 8.2 0.0 2.2 2 0 0 2 2 2 0 Fanconi anemia group F protein (FANCF) TBPIP PF07106.13 KKK21583.1 - 0.11 12.4 0.0 0.39 10.7 0.0 1.9 1 0 0 1 1 1 0 TBPIP/Hop2 winged helix domain CLPTM1 PF05602.12 KKK21584.1 - 4e-161 536.8 0.0 4.8e-161 536.6 0.0 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) adh_short PF00106.25 KKK21585.1 - 1.5e-12 47.3 0.0 4e-12 46.0 0.0 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KKK21585.1 - 1.7e-08 34.3 0.0 2.5e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Mak16 PF04874.14 KKK21586.1 - 1.2e-30 106.0 11.5 1.2e-30 106.0 11.5 2.4 2 0 0 2 2 2 1 Mak16 protein C-terminal region Ribosomal_L28e PF01778.17 KKK21586.1 - 2.2e-09 38.1 0.0 4.3e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 Ribosomal L28e protein family BUD22 PF09073.10 KKK21586.1 - 1.1e-05 25.0 17.7 1.4e-05 24.7 17.7 1.1 1 0 0 1 1 1 1 BUD22 TFIIF_alpha PF05793.12 KKK21586.1 - 5.1 5.6 36.2 5.8 5.4 36.2 1.2 1 1 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SGT1 PF07093.11 KKK21586.1 - 5.9 5.2 9.9 8.4 4.7 9.9 1.3 1 0 0 1 1 1 0 SGT1 protein SAPS PF04499.15 KKK21586.1 - 9.1 4.9 7.6 11 4.7 7.6 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Mso1_Sec1_bdg PF14475.6 KKK21587.1 - 9.9e-14 50.7 0.1 1.7e-13 49.9 0.1 1.4 1 0 0 1 1 1 1 Sec1-binding region of Mso1 Longin PF13774.6 KKK21588.1 - 1.1e-26 92.6 0.5 1.7e-26 92.1 0.5 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.21 KKK21588.1 - 1.5e-13 50.3 0.0 3.1e-13 49.3 0.0 1.6 1 0 0 1 1 1 1 Synaptobrevin SLM4 PF16818.5 KKK21588.1 - 0.019 14.9 0.6 0.51 10.3 0.1 2.2 1 1 1 2 2 2 0 Protein SLM4 ASXH PF13919.6 KKK21589.1 - 3.7e-18 65.9 5.8 3.5e-17 62.7 5.8 2.2 1 1 0 1 1 1 1 Asx homology domain PhoLip_ATPase_C PF16212.5 KKK21590.1 - 5e-46 157.5 13.4 5e-46 157.5 13.4 2.5 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KKK21590.1 - 2.3e-16 59.2 0.8 5.1e-16 58.1 0.8 1.5 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 KKK21590.1 - 4.8e-14 53.2 1.4 1.8e-11 44.7 0.5 2.9 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KKK21590.1 - 2.4e-07 30.8 0.0 5.8e-06 26.3 0.0 2.8 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 KKK21590.1 - 3.3e-07 30.0 0.4 0.002 17.7 0.0 2.6 2 0 0 2 2 2 2 E1-E2 ATPase Hydrolase_3 PF08282.12 KKK21590.1 - 0.0064 16.3 0.0 0.014 15.1 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Elong_Iki1 PF10483.9 KKK21591.1 - 9e-102 340.6 0.0 1e-101 340.4 0.0 1.0 1 0 0 1 1 1 1 Elongator subunit Iki1 cobW PF02492.19 KKK21596.1 - 2.7e-36 124.8 0.0 4e-36 124.2 0.0 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 KKK21596.1 - 0.016 15.1 0.0 0.16 11.9 0.0 2.6 2 1 0 2 2 2 0 Cobalamin synthesis protein cobW C-terminal domain MobB PF03205.14 KKK21596.1 - 0.3 11.0 0.0 0.3 11.0 0.0 1.9 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B SelP_N PF04592.14 KKK21596.1 - 1.7 8.0 9.2 3.2 7.1 9.2 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Orn_Arg_deC_N PF02784.16 KKK21597.1 - 9.3e-82 274.1 0.0 1.2e-81 273.8 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 KKK21597.1 - 3.1e-20 72.2 0.0 6.3e-20 71.2 0.0 1.6 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain AP_endonuc_2 PF01261.24 KKK21597.1 - 0.0063 16.0 0.0 0.024 14.1 0.0 1.8 2 0 0 2 2 2 1 Xylose isomerase-like TIM barrel CUE PF02845.16 KKK21598.1 - 3.1e-12 46.0 0.0 5.3e-12 45.2 0.0 1.4 1 0 0 1 1 1 1 CUE domain DUF3602 PF12223.8 KKK21599.1 - 1e-22 80.5 2.8 4.9e-21 75.1 0.5 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF3602) zf-U1 PF06220.12 KKK21600.1 - 9.5e-07 28.5 0.9 1.2e-06 28.1 0.9 1.2 1 0 0 1 1 1 1 U1 zinc finger Coatomer_E PF04733.14 KKK21600.1 - 0.22 10.9 0.0 0.25 10.7 0.0 1.0 1 0 0 1 1 1 0 Coatomer epsilon subunit Bax1-I PF01027.20 KKK21601.1 - 1.3e-51 175.4 31.0 1.5e-51 175.2 31.0 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Ycf4 PF02392.16 KKK21601.1 - 0.26 10.9 3.2 0.64 9.6 3.2 1.6 1 0 0 1 1 1 0 Ycf4 DUF5504 PF17608.2 KKK21601.1 - 0.37 10.9 16.2 0.025 14.7 6.6 2.2 1 1 1 2 2 2 0 Family of unknown function (DUF5504) SUR7 PF06687.12 KKK21616.1 - 1.7e-39 135.7 3.8 2e-39 135.4 3.8 1.0 1 0 0 1 1 1 1 SUR7/PalI family DUF348 PF03990.14 KKK21616.1 - 0.00042 20.0 1.9 0.00079 19.1 1.9 1.4 1 0 0 1 1 1 1 G5-linked-Ubiquitin-like domain RICTOR_M PF14666.6 KKK21616.1 - 0.058 13.2 0.0 0.094 12.5 0.0 1.3 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, middle domain DUF5362 PF17319.2 KKK21616.1 - 0.23 11.3 3.7 8.1 6.4 0.0 2.9 3 0 0 3 3 3 0 Family of unknown function (DUF5362) SurA_N_3 PF13624.6 KKK21616.1 - 4.7 7.0 4.9 6 6.6 0.1 2.5 2 1 0 3 3 3 0 SurA N-terminal domain Pkinase PF00069.25 KKK21626.1 - 1.1e-34 120.0 0.0 3.3e-17 62.7 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KKK21626.1 - 4.5e-16 58.9 0.0 3.6e-14 52.7 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Amidoligase_2 PF12224.8 KKK21627.1 - 1.5e-10 41.2 0.0 1.8e-10 41.0 0.0 1.1 1 0 0 1 1 1 1 Putative amidoligase enzyme GGACT PF06094.12 KKK21628.1 - 2.4e-11 44.3 0.0 2.8e-11 44.1 0.0 1.1 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like Apc15p PF05841.11 KKK21629.1 - 1.2e-15 58.4 0.0 2.4e-15 57.4 0.0 1.5 1 0 0 1 1 1 1 Apc15p protein GATase_2 PF00310.21 KKK21630.1 - 1.1e-181 604.1 0.0 1.5e-181 603.7 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_synthase PF01645.17 KKK21630.1 - 9.9e-156 518.5 0.0 1.4e-155 518.0 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase Glu_syn_central PF04898.14 KKK21630.1 - 1.1e-89 300.7 0.4 1.2e-71 241.5 0.1 3.2 2 1 1 3 3 3 3 Glutamate synthase central domain GXGXG PF01493.19 KKK21630.1 - 6.5e-86 286.8 2.6 1.1e-85 286.0 2.6 1.4 1 0 0 1 1 1 1 GXGXG motif Pyr_redox_2 PF07992.14 KKK21630.1 - 5.8e-26 91.4 0.1 3.3e-25 88.9 0.1 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_20 PF14691.6 KKK21630.1 - 2.9e-21 75.3 0.1 6e-21 74.3 0.1 1.5 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster NAD_binding_8 PF13450.6 KKK21630.1 - 1e-08 35.2 0.0 3.5e-08 33.5 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KKK21630.1 - 1.1e-08 34.7 1.6 0.012 14.8 0.0 4.4 3 1 1 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KKK21630.1 - 6.5e-08 33.0 0.4 7.9e-05 23.1 0.1 3.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KKK21630.1 - 1.4e-07 31.4 2.1 0.0027 17.4 0.7 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Amino_oxidase PF01593.24 KKK21630.1 - 4.4e-07 29.5 0.2 7.7e-07 28.8 0.2 1.4 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase FAD_oxidored PF12831.7 KKK21630.1 - 2.1e-05 24.1 0.2 4.1e-05 23.1 0.2 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KKK21630.1 - 2.8e-05 23.4 0.1 0.00041 19.5 0.1 2.5 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 KKK21630.1 - 0.00011 21.1 0.2 0.00011 21.1 0.2 1.6 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_7 PF13241.6 KKK21630.1 - 0.00056 20.3 0.2 2.9 8.4 0.0 3.1 3 0 0 3 3 2 2 Putative NAD(P)-binding FAD_binding_3 PF01494.19 KKK21630.1 - 0.00096 18.5 0.0 0.0027 17.0 0.0 1.7 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.21 KKK21630.1 - 0.0021 17.4 0.2 0.44 9.8 0.1 2.4 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain FMN_dh PF01070.18 KKK21630.1 - 0.003 16.6 1.7 0.013 14.6 1.0 2.3 3 0 0 3 3 3 1 FMN-dependent dehydrogenase Thi4 PF01946.17 KKK21630.1 - 0.012 14.9 0.3 0.04 13.2 0.1 1.9 2 0 0 2 2 2 0 Thi4 family FMO-like PF00743.19 KKK21630.1 - 0.035 12.5 0.1 2.1 6.6 0.0 2.7 3 0 0 3 3 3 0 Flavin-binding monooxygenase-like Lycopene_cycl PF05834.12 KKK21630.1 - 0.064 12.3 0.3 0.48 9.4 0.2 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein ApbA PF02558.16 KKK21630.1 - 0.12 12.0 0.1 1 9.0 0.1 2.2 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.17 KKK21630.1 - 0.13 12.9 0.1 1.9 9.1 0.1 2.7 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent GIDA PF01134.22 KKK21630.1 - 0.13 11.3 3.0 0.076 12.1 0.2 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A 2-Hacid_dh_C PF02826.19 KKK21630.1 - 0.14 11.5 0.2 0.42 9.9 0.0 1.8 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_9 PF13454.6 KKK21630.1 - 0.17 11.9 0.1 0.79 9.7 0.1 2.2 1 0 0 1 1 1 0 FAD-NAD(P)-binding p450 PF00067.22 KKK21631.1 - 1.5e-21 76.7 0.0 8.8e-21 74.2 0.0 2.2 1 1 0 1 1 1 1 Cytochrome P450 Peptidase_C14 PF00656.22 KKK21632.1 - 1.3e-05 25.3 0.0 1.6e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Caspase domain Raptor_N PF14538.6 KKK21632.1 - 0.00095 19.1 0.1 0.0057 16.6 0.1 2.4 2 1 0 2 2 2 1 Raptor N-terminal CASPase like domain DUF3128 PF11326.8 KKK21633.1 - 2.2e-27 95.2 3.0 3.6e-27 94.5 3.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) Ndc1_Nup PF09531.10 KKK21633.1 - 1.1 7.9 3.6 1.1 7.9 3.6 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup RNA12 PF10443.9 KKK21634.1 - 3.8e-173 576.3 0.0 2.8e-171 570.1 0.0 2.2 1 1 0 1 1 1 1 RNA12 protein ATPase_2 PF01637.18 KKK21634.1 - 5.5e-06 26.5 0.0 1.2e-05 25.3 0.0 1.7 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea RRM_1 PF00076.22 KKK21634.1 - 2.3e-05 24.1 0.0 0.00014 21.6 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAA_16 PF13191.6 KKK21634.1 - 0.0029 18.0 0.0 0.01 16.2 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain DUF2487 PF10673.9 KKK21634.1 - 0.014 15.4 0.0 0.043 13.8 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2487) ScsC_N PF18312.1 KKK21634.1 - 0.22 11.4 2.7 1.1 9.2 0.0 2.5 2 0 0 2 2 2 0 Copper resistance protein ScsC N-terminal domain Helicase_C PF00271.31 KKK21656.1 - 1.4e-13 51.2 0.0 2.3e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RNase_PH PF01138.21 KKK21658.1 - 1.2e-16 61.4 0.0 1.8e-16 60.8 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KKK21658.1 - 9.1e-06 25.6 0.0 1.9e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Cwf_Cwc_15 PF04889.12 KKK21659.1 - 1.9e-81 273.5 12.5 3.1e-81 272.8 12.5 1.3 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein Med22 PF06179.12 KKK21659.1 - 7.4e-18 64.7 3.3 7.4e-18 64.7 3.3 2.2 2 1 1 3 3 3 1 Surfeit locus protein 5 subunit 22 of Mediator complex CDC45 PF02724.14 KKK21659.1 - 0.2 9.9 9.7 0.24 9.7 9.7 1.1 1 0 0 1 1 1 0 CDC45-like protein PdaC PF13739.6 KKK21659.1 - 0.48 11.4 2.3 6.1 7.9 0.0 2.5 2 0 0 2 2 2 0 Deacetylase PdaC DHFR_1 PF00186.19 KKK21660.1 - 5.6e-18 65.1 0.1 8.9e-07 28.7 0.1 3.2 2 1 1 3 3 3 3 Dihydrofolate reductase Mito_fiss_reg PF05308.11 KKK21660.1 - 0.16 12.0 1.9 0.21 11.6 1.9 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 KKK21660.1 - 6.7 6.1 9.3 9.7 5.6 9.3 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Voltage_CLC PF00654.20 KKK21661.1 - 4.9e-88 295.8 22.1 4.9e-88 295.8 22.1 1.9 2 0 0 2 2 2 1 Voltage gated chloride channel Pectate_lyase PF03211.13 KKK21662.1 - 2.1e-83 278.8 6.3 2.4e-83 278.7 6.3 1.0 1 0 0 1 1 1 1 Pectate lyase Lipase_GDSL_2 PF13472.6 KKK21663.1 - 6.6e-25 88.5 0.0 1.4e-24 87.5 0.0 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KKK21663.1 - 2.8e-17 63.4 0.0 3.4e-17 63.1 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase PhoLip_ATPase_C PF16212.5 KKK21664.1 - 5.6e-81 272.0 16.1 5.6e-81 272.0 16.1 1.8 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KKK21664.1 - 1.8e-24 85.2 7.5 1.8e-24 85.2 7.5 1.9 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 KKK21664.1 - 7.6e-11 41.9 0.0 3e-10 40.0 0.0 1.9 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KKK21664.1 - 5.4e-10 39.9 1.9 1.3e-05 25.6 0.5 3.3 1 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 KKK21664.1 - 1.1e-05 25.1 0.0 2.7e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KKK21664.1 - 0.0054 16.5 0.0 0.018 14.8 0.0 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Acetyltransf_1 PF00583.25 KKK21665.1 - 1.3e-10 41.5 0.0 1.6e-10 41.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KKK21665.1 - 5.6e-09 36.3 0.0 7.7e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KKK21665.1 - 4.2e-08 33.1 0.0 6e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 KKK21665.1 - 1.1e-07 31.8 0.0 1.2e-07 31.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.7 KKK21665.1 - 0.00062 19.9 0.0 0.00082 19.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KKK21665.1 - 0.0013 18.8 0.0 0.0022 18.1 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase PanZ PF12568.8 KKK21665.1 - 0.003 17.3 0.1 0.0039 16.9 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain, PanZ MOZART1 PF12554.8 KKK21666.1 - 1.5e-24 85.5 1.5 1.8e-24 85.2 1.5 1.1 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated DUF1844 PF08899.11 KKK21666.1 - 0.099 12.9 0.1 0.2 12.0 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1844) CUE PF02845.16 KKK21667.1 - 3.4e-10 39.4 0.0 5.8e-10 38.7 0.0 1.3 1 0 0 1 1 1 1 CUE domain HA2 PF04408.23 KKK21668.1 - 8.7e-17 61.4 0.0 1.8e-16 60.4 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KKK21668.1 - 8.4e-13 48.5 0.0 2.2e-12 47.2 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KKK21668.1 - 4.3e-12 46.4 0.0 9.4e-12 45.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KKK21668.1 - 1.1e-05 25.3 0.0 2.1e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KKK21668.1 - 0.0001 22.6 0.0 0.00028 21.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KKK21668.1 - 0.00016 21.5 0.0 0.00032 20.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KKK21668.1 - 0.00021 21.6 0.0 0.00054 20.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain cobW PF02492.19 KKK21668.1 - 0.018 14.6 0.1 0.079 12.5 0.0 1.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain T2SSE PF00437.20 KKK21668.1 - 0.026 13.6 0.2 0.095 11.7 0.0 1.9 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_14 PF13173.6 KKK21668.1 - 0.033 14.2 0.1 3.6 7.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain Herpes_ori_bp PF02399.15 KKK21668.1 - 0.037 12.1 0.0 0.055 11.5 0.0 1.2 1 0 0 1 1 1 0 Origin of replication binding protein DUF2075 PF09848.9 KKK21668.1 - 0.073 12.3 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) FBPase_2 PF06874.11 KKK21668.1 - 0.078 11.3 0.0 0.13 10.6 0.0 1.2 1 0 0 1 1 1 0 Firmicute fructose-1,6-bisphosphatase AAA_23 PF13476.6 KKK21668.1 - 0.088 13.3 0.0 0.3 11.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain PITH PF06201.13 KKK21669.1 - 1.5e-43 148.6 0.0 1.8e-43 148.4 0.0 1.1 1 0 0 1 1 1 1 PITH domain NicO PF03824.16 KKK21669.1 - 2.1 7.6 3.7 2.8 7.2 3.7 1.1 1 0 0 1 1 1 0 High-affinity nickel-transport protein Snf7 PF03357.21 KKK21670.1 - 1e-35 122.9 2.5 1.5e-35 122.3 2.5 1.2 1 0 0 1 1 1 1 Snf7 MR_MLE_N PF02746.16 KKK21670.1 - 0.041 14.1 0.1 0.31 11.2 0.0 2.2 2 0 0 2 2 2 0 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain AAA PF00004.29 KKK21671.1 - 7.7e-79 262.6 0.0 2.9e-42 144.2 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KKK21671.1 - 3.9e-14 53.4 0.8 0.00018 21.9 0.0 4.4 2 2 1 3 3 3 2 AAA ATPase domain RuvB_N PF05496.12 KKK21671.1 - 4.9e-14 52.4 0.0 1.4e-06 28.2 0.0 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KKK21671.1 - 1.8e-12 47.7 0.6 0.0074 16.6 0.0 4.8 3 2 2 5 5 4 2 AAA domain AAA_2 PF07724.14 KKK21671.1 - 4e-11 43.3 0.0 8.5e-05 22.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 KKK21671.1 - 1.4e-10 41.5 0.0 4.6e-05 23.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 KKK21671.1 - 1.4e-10 41.3 0.3 0.0006 19.8 0.1 3.8 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_lid_3 PF17862.1 KKK21671.1 - 2.5e-10 40.0 0.0 1.2e-09 37.8 0.0 2.2 1 0 0 1 1 1 1 AAA+ lid domain TIP49 PF06068.13 KKK21671.1 - 4.2e-09 36.1 0.0 8.7e-05 21.9 0.0 2.4 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_14 PF13173.6 KKK21671.1 - 3.3e-08 33.6 0.0 0.0032 17.5 0.0 2.8 3 0 0 3 3 2 2 AAA domain RNA_helicase PF00910.22 KKK21671.1 - 7.7e-08 32.7 0.0 0.0072 16.7 0.0 2.7 2 1 0 2 2 2 2 RNA helicase Mg_chelatase PF01078.21 KKK21671.1 - 2.8e-07 30.2 0.6 0.017 14.5 0.1 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 KKK21671.1 - 4.3e-07 30.3 0.0 0.012 15.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 KKK21671.1 - 4.4e-07 29.8 0.1 0.025 14.3 0.0 2.6 2 1 0 2 2 2 2 IstB-like ATP binding protein AAA_18 PF13238.6 KKK21671.1 - 4.7e-07 30.4 0.0 0.027 15.0 0.0 3.2 3 1 0 3 3 2 2 AAA domain AAA_3 PF07726.11 KKK21671.1 - 9.5e-07 28.7 0.0 0.0029 17.5 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 KKK21671.1 - 1.6e-06 27.6 0.0 0.052 12.8 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin AAA_25 PF13481.6 KKK21671.1 - 3.5e-06 26.7 0.8 0.69 9.5 0.0 4.1 3 1 0 4 4 4 2 AAA domain NACHT PF05729.12 KKK21671.1 - 4e-06 26.8 0.2 0.11 12.4 0.0 3.7 3 1 1 4 4 4 2 NACHT domain TsaE PF02367.17 KKK21671.1 - 4.1e-06 26.8 0.0 0.07 13.1 0.0 2.3 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Rad17 PF03215.15 KKK21671.1 - 6.7e-06 26.1 0.0 0.038 13.9 0.0 2.4 2 0 0 2 2 2 2 Rad17 P-loop domain AAA_7 PF12775.7 KKK21671.1 - 8e-06 25.5 0.0 0.04 13.4 0.0 2.7 2 1 0 2 2 2 2 P-loop containing dynein motor region Cytidylate_kin2 PF13189.6 KKK21671.1 - 8.1e-06 26.1 0.0 0.0015 18.7 0.0 2.3 2 0 0 2 2 2 1 Cytidylate kinase-like family ATPase PF06745.13 KKK21671.1 - 1.7e-05 24.3 0.1 0.41 9.9 0.0 3.3 2 1 1 3 3 3 2 KaiC ABC_tran PF00005.27 KKK21671.1 - 2.1e-05 25.0 0.0 0.24 11.9 0.0 2.8 3 0 0 3 3 2 2 ABC transporter AAA_17 PF13207.6 KKK21671.1 - 3.7e-05 24.2 0.0 0.076 13.4 0.0 2.9 2 1 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 KKK21671.1 - 8.5e-05 22.3 0.0 0.27 10.9 0.0 2.9 3 0 0 3 3 3 2 Sigma-54 interaction domain TniB PF05621.11 KKK21671.1 - 0.00012 21.6 0.0 0.19 11.1 0.0 3.3 3 0 0 3 3 3 1 Bacterial TniB protein PhoH PF02562.16 KKK21671.1 - 0.00015 21.3 0.0 0.3 10.5 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein AAA_11 PF13086.6 KKK21671.1 - 0.00018 21.4 2.2 0.96 9.2 0.0 3.2 3 0 0 3 3 3 2 AAA domain AFG1_ATPase PF03969.16 KKK21671.1 - 0.00029 19.8 0.1 0.071 12.0 0.0 2.5 2 1 0 2 2 2 1 AFG1-like ATPase SKI PF01202.22 KKK21671.1 - 0.00036 20.7 0.0 0.48 10.5 0.0 2.8 2 0 0 2 2 2 1 Shikimate kinase AAA_24 PF13479.6 KKK21671.1 - 0.00045 20.0 0.0 0.75 9.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain Sigma54_activ_2 PF14532.6 KKK21671.1 - 0.00056 20.0 0.0 1.8 8.7 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain NB-ARC PF00931.22 KKK21671.1 - 0.00057 19.2 0.0 0.81 8.8 0.0 2.8 3 0 0 3 3 3 2 NB-ARC domain Parvo_NS1 PF01057.17 KKK21671.1 - 0.00086 18.5 0.0 1.3 8.0 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 ATPase_2 PF01637.18 KKK21671.1 - 0.0013 18.7 0.0 1.5 8.6 0.0 3.2 2 2 1 3 3 2 1 ATPase domain predominantly from Archaea Viral_helicase1 PF01443.18 KKK21671.1 - 0.0017 18.2 0.0 1.1 8.9 0.0 2.5 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase DUF815 PF05673.13 KKK21671.1 - 0.0036 16.5 0.0 0.095 11.8 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_19 PF13245.6 KKK21671.1 - 0.0062 16.9 2.3 2.1 8.7 0.3 3.3 2 1 0 2 2 2 1 AAA domain IPT PF01745.16 KKK21671.1 - 0.0092 15.4 0.0 1.1 8.6 0.0 2.4 2 0 0 2 2 2 1 Isopentenyl transferase DUF384 PF04064.13 KKK21671.1 - 0.012 15.5 0.5 0.04 13.8 0.2 2.1 2 0 0 2 2 1 0 Domain of unknown function (DUF384) DUF2075 PF09848.9 KKK21671.1 - 0.021 14.1 0.0 2.5 7.2 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) NTPase_1 PF03266.15 KKK21671.1 - 0.024 14.5 0.0 5.4 6.9 0.0 2.9 2 1 1 3 3 3 0 NTPase CPT PF07931.12 KKK21671.1 - 0.025 14.4 0.0 0.76 9.6 0.0 2.5 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein AAA_30 PF13604.6 KKK21671.1 - 0.026 14.2 0.1 15 5.2 0.0 3.2 4 0 0 4 4 3 0 AAA domain ResIII PF04851.15 KKK21671.1 - 0.03 14.3 0.0 11 5.9 0.0 2.8 3 0 0 3 3 2 0 Type III restriction enzyme, res subunit Hydin_ADK PF17213.3 KKK21671.1 - 0.07 13.4 5.0 2 8.7 0.0 3.1 3 0 0 3 3 3 0 Hydin Adenylate kinase-like domain Cytidylate_kin PF02224.18 KKK21671.1 - 0.071 12.8 0.1 6.2 6.5 0.0 2.4 2 0 0 2 2 2 0 Cytidylate kinase SRPRB PF09439.10 KKK21671.1 - 0.14 11.6 0.0 17 4.8 0.0 2.8 3 0 0 3 3 2 0 Signal recognition particle receptor beta subunit AAA_23 PF13476.6 KKK21671.1 - 0.16 12.5 1.6 4.3 7.8 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_lid_3 PF17862.1 KKK21672.1 - 7.8e-11 41.6 0.1 1.2e-10 41.1 0.1 1.3 1 0 0 1 1 1 1 AAA+ lid domain Vps4_C PF09336.10 KKK21672.1 - 0.11 12.5 0.1 0.23 11.5 0.1 1.5 1 0 0 1 1 1 0 Vps4 C terminal oligomerisation domain He_PIG PF05345.12 KKK21673.1 - 3.8e-15 55.8 10.0 0.00013 22.1 0.1 4.9 4 0 0 4 4 4 3 Putative Ig domain BACON PF13004.7 KKK21673.1 - 0.00017 21.5 5.0 0.36 10.9 0.4 3.9 3 0 0 3 3 3 3 Putative binding domain, N-terminal PMP1_2 PF08114.11 KKK21673.1 - 0.32 10.8 0.8 0.7 9.7 0.8 1.5 1 0 0 1 1 1 0 ATPase proteolipid family Putative_PNPOx PF01243.20 KKK21685.1 - 5.6e-10 39.3 0.0 2.3e-09 37.3 0.0 2.0 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase Chordopox_G3 PF06129.12 KKK21685.1 - 0.061 14.0 0.0 0.1 13.3 0.0 1.3 1 0 0 1 1 1 0 Chordopoxvirus G3 protein WD40 PF00400.32 KKK21686.1 - 2.9e-08 34.2 5.0 0.00053 20.7 0.2 5.1 4 1 0 4 4 4 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKK21686.1 - 0.00025 21.3 0.0 17 5.8 0.0 4.2 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 KKK21686.1 - 0.013 14.2 0.1 0.14 10.8 0.0 2.1 2 0 0 2 2 2 0 Nup133 N terminal like Gryzun-like PF12742.7 KKK21686.1 - 0.027 14.5 0.0 0.051 13.6 0.0 1.4 1 0 0 1 1 1 0 Gryzun, putative Golgi trafficking Oxysterol_BP PF01237.18 KKK21686.1 - 0.15 10.9 3.3 0.27 10.0 3.3 1.3 1 0 0 1 1 1 0 Oxysterol-binding protein Csm1_N PF18504.1 KKK21686.1 - 1.1 9.7 5.5 1.9 8.9 0.8 2.6 1 1 1 2 2 2 0 Csm1 N-terminal domain DUF4407 PF14362.6 KKK21686.1 - 2.5 7.4 8.2 3.8 6.8 8.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Spc7 PF08317.11 KKK21686.1 - 2.6 6.8 10.1 3.8 6.3 10.1 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Atg14 PF10186.9 KKK21686.1 - 4.2 6.4 7.9 7 5.6 7.9 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DeoC PF01791.9 KKK21687.1 - 2.4e-11 43.7 2.6 3.4e-11 43.2 2.6 1.1 1 0 0 1 1 1 1 DeoC/LacD family aldolase DHO_dh PF01180.21 KKK21687.1 - 0.0064 15.7 1.5 0.011 14.9 1.5 1.5 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase FMN_dh PF01070.18 KKK21687.1 - 0.022 13.8 3.7 0.053 12.5 3.7 1.6 1 1 0 1 1 1 0 FMN-dependent dehydrogenase His_biosynth PF00977.21 KKK21687.1 - 0.041 13.3 0.3 0.08 12.4 0.3 1.4 1 0 0 1 1 1 0 Histidine biosynthesis protein TP_methylase PF00590.20 KKK21688.1 - 1.2e-48 165.9 0.0 1.9e-48 165.3 0.0 1.3 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_7 PF13241.6 KKK21688.1 - 9.9e-16 58.1 0.0 1.8e-15 57.2 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.6 KKK21688.1 - 5.7e-13 48.3 0.1 5.7e-09 35.5 0.1 2.6 2 0 0 2 2 2 2 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.6 KKK21688.1 - 1.4e-06 27.6 0.1 3.3e-06 26.4 0.1 1.7 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central PCI PF01399.27 KKK21689.1 - 1.9e-20 73.3 0.0 4.9e-20 72.0 0.0 1.7 1 0 0 1 1 1 1 PCI domain RPN5_C PF18098.1 KKK21689.1 - 2e-16 59.7 1.2 5e-16 58.5 1.2 1.7 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN5 C-terminal domain DUF2935 PF11155.8 KKK21689.1 - 0.42 10.9 2.0 0.91 9.9 0.0 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF2935) ERp29 PF07749.12 KKK21689.1 - 2.1 9.3 5.2 7.4 7.6 0.0 3.4 3 0 0 3 3 3 0 Endoplasmic reticulum protein ERp29, C-terminal domain FSH1 PF03959.13 KKK21690.1 - 2.9e-73 246.0 0.0 7.4e-73 244.7 0.0 1.6 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 KKK21690.1 - 0.0068 16.2 1.3 1 9.1 1.0 2.9 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase Esterase_phd PF10503.9 KKK21690.1 - 0.045 13.2 0.3 0.73 9.3 0.8 2.1 2 0 0 2 2 2 0 Esterase PHB depolymerase Hydrolase_4 PF12146.8 KKK21690.1 - 0.086 12.1 0.0 0.32 10.2 0.0 1.9 2 1 0 2 2 2 0 Serine aminopeptidase, S33 SR-25 PF10500.9 KKK21690.1 - 0.99 9.0 15.0 1.5 8.4 15.0 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Ribosomal_S27e PF01667.17 KKK21691.1 - 1e-28 98.8 6.9 1.3e-28 98.5 6.9 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 zf-C2HC5 PF06221.13 KKK21691.1 - 0.41 10.7 6.2 1.2 9.2 2.6 2.3 2 1 0 2 2 2 0 Putative zinc finger motif, C2HC5-type Prok-RING_1 PF14446.6 KKK21691.1 - 0.42 10.6 4.1 0.75 9.8 4.1 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 CDP-OH_P_transf PF01066.21 KKK21692.1 - 1.3e-16 61.1 0.1 1.3e-16 61.1 0.1 3.3 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase NIPSNAP PF07978.13 KKK21693.1 - 2e-40 137.1 5.8 4.5e-29 100.7 0.1 2.7 3 0 0 3 3 3 2 NIPSNAP LIAS_N PF16881.5 KKK21695.1 - 1.3e-26 93.2 0.0 2.4e-26 92.3 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of lipoyl synthase of Radical_SAM family Radical_SAM PF04055.21 KKK21695.1 - 1.2e-14 55.0 0.0 1.8e-14 54.5 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Abhydrolase_6 PF12697.7 KKK21696.1 - 2.2e-05 25.2 1.7 3.1e-05 24.7 1.7 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KKK21696.1 - 0.044 13.0 0.0 0.65 9.2 0.0 2.2 2 0 0 2 2 2 0 Serine aminopeptidase, S33 ORC5_C PF14630.6 KKK21696.1 - 0.19 11.2 0.0 0.26 10.7 0.0 1.2 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 5 C-terminus Helicase_C_2 PF13307.6 KKK21697.1 - 2.4e-52 177.5 0.0 5.8e-52 176.3 0.0 1.6 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.15 KKK21697.1 - 1.2e-50 171.5 0.0 2.1e-50 170.8 0.0 1.4 1 0 0 1 1 1 1 DEAD_2 Ribosomal_L27A PF00828.19 KKK21697.1 - 3.7e-21 76.1 0.0 7.4e-21 75.2 0.0 1.5 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A DEAD PF00270.29 KKK21697.1 - 0.0032 17.2 0.0 2 8.1 0.0 2.4 2 0 0 2 2 2 2 DEAD/DEAH box helicase Dor1 PF04124.12 KKK21697.1 - 0.011 14.4 0.7 0.02 13.6 0.7 1.3 1 0 0 1 1 1 0 Dor1-like family HBB PF06777.11 KKK21697.1 - 0.041 13.5 0.0 0.12 12.0 0.0 1.8 1 0 0 1 1 1 0 Helical and beta-bridge domain Alkyl_sulf_dimr PF14863.6 KKK21698.1 - 0.12 12.8 0.1 0.21 12.1 0.1 1.3 1 0 0 1 1 1 0 Alkyl sulfatase dimerisation Ion_trans_2 PF07885.16 KKK21699.1 - 6.8e-25 86.8 22.8 1e-14 54.2 9.1 3.4 3 1 0 3 3 3 2 Ion channel Ion_trans PF00520.31 KKK21699.1 - 0.0023 17.2 19.0 0.17 11.1 0.3 3.2 2 1 1 3 3 3 3 Ion transport protein Exo5 PF09810.9 KKK21712.1 - 2.9e-133 444.9 0.0 3.7e-133 444.6 0.0 1.1 1 0 0 1 1 1 1 Exonuclease V - a 5' deoxyribonuclease PDDEXK_1 PF12705.7 KKK21712.1 - 0.00039 20.4 0.0 0.5 10.2 0.0 3.0 2 1 0 2 2 2 2 PD-(D/E)XK nuclease superfamily DUF3799 PF12684.7 KKK21712.1 - 0.083 12.6 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 PDDEXK-like domain of unknown function (DUF3799) Transglut_core PF01841.19 KKK21713.1 - 8.8e-11 42.3 0.0 1.9e-10 41.2 0.0 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily WD40 PF00400.32 KKK21714.1 - 2.3e-17 63.0 0.3 0.00074 20.3 0.0 7.4 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKK21714.1 - 4.4e-07 30.1 0.0 0.00039 20.7 0.0 3.9 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KKK21714.1 - 0.0027 16.7 0.0 0.18 10.7 0.0 2.9 3 0 0 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KKK21714.1 - 0.19 11.7 0.1 0.7 9.9 0.0 2.0 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat NDUF_B12 PF08122.12 KKK21715.1 - 1.5e-27 95.4 1.6 2e-27 95.0 1.6 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family LOR PF04525.12 KKK21716.1 - 2.9e-07 30.3 0.0 1.1e-06 28.4 0.0 1.9 1 1 0 1 1 1 1 LURP-one-related CAF1 PF04857.20 KKK21717.1 - 1.2e-21 77.2 0.0 2e-10 40.4 0.0 2.1 2 0 0 2 2 2 2 CAF1 family ribonuclease Cu_amine_oxid PF01179.20 KKK21718.1 - 8.2e-157 522.3 0.0 1.1e-156 521.9 0.0 1.2 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 KKK21718.1 - 3.5e-22 78.7 1.1 5.4e-21 74.9 0.1 2.4 1 1 1 2 2 2 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.16 KKK21718.1 - 4.6e-14 52.4 0.0 8.4e-14 51.6 0.0 1.4 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Lipase_GDSL PF00657.22 KKK21719.1 - 1.6e-11 44.6 0.0 2.2e-11 44.1 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 KKK21719.1 - 5.3e-05 23.7 2.3 0.00011 22.7 2.3 1.8 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family AMP-binding PF00501.28 KKK21720.1 - 2.1e-75 253.9 0.0 2.7e-75 253.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KKK21720.1 - 8e-14 52.4 0.2 1.9e-13 51.2 0.2 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain PPTA PF01239.22 KKK21721.1 - 8.2e-39 130.2 14.5 4e-08 32.7 0.1 5.4 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat DUF5072 PF16807.5 KKK21721.1 - 0.051 13.6 0.1 0.48 10.5 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5072) RabGAP-TBC PF00566.18 KKK21722.1 - 6.2e-54 182.9 0.0 2.4e-53 181.0 0.0 1.9 1 1 0 1 1 1 1 Rab-GTPase-TBC domain Fibin PF15819.5 KKK21722.1 - 1.1 8.9 7.3 2.4 7.9 0.1 2.4 2 0 0 2 2 2 0 Fin bud initiation factor homologue Med9 PF07544.13 KKK21722.1 - 3.5 7.8 8.8 0.63 10.2 0.4 3.4 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DUF1664 PF07889.12 KKK21722.1 - 7.2 6.7 11.6 3.5 7.7 8.6 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Fez1 PF06818.15 KKK21722.1 - 8.4 6.8 22.4 0.6 10.5 14.7 2.3 2 0 0 2 2 2 0 Fez1 DHHC PF01529.20 KKK21723.1 - 5.1e-34 117.3 4.2 5.1e-34 117.3 4.2 1.7 2 0 0 2 2 2 1 DHHC palmitoyltransferase SET PF00856.28 KKK21724.1 - 1.8e-13 51.2 0.2 1.8e-13 51.2 0.2 3.7 3 2 0 3 3 3 1 SET domain AWS PF17907.1 KKK21724.1 - 1.1e-07 31.7 5.3 1.1e-07 31.7 5.3 2.1 2 0 0 2 2 2 1 AWS domain Ribosomal_L24e PF01246.20 KKK21733.1 - 3.8e-29 100.7 0.1 1.1e-28 99.3 0.1 1.8 1 0 0 1 1 1 1 Ribosomal protein L24e Zn_ribbon_17 PF17120.5 KKK21734.1 - 1.9e-08 33.8 20.1 3.3e-05 23.4 10.4 2.9 2 0 0 2 2 2 2 Zinc-ribbon, C4HC2 type WD40 PF00400.32 KKK21734.1 - 1e-06 29.3 24.3 0.0033 18.2 0.1 6.9 6 0 0 6 6 6 3 WD domain, G-beta repeat RWD PF05773.22 KKK21734.1 - 0.0041 17.4 0.0 0.0089 16.3 0.0 1.5 1 0 0 1 1 1 1 RWD domain zf-RING_14 PF17978.1 KKK21734.1 - 4.7 7.7 9.3 11 6.5 9.3 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Mito_carr PF00153.27 KKK21746.1 - 3.2e-52 174.4 5.5 1.3e-22 79.5 0.2 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein IBR PF01485.21 KKK21747.1 - 4.3e-22 78.1 49.0 7.3e-12 45.3 8.9 4.4 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain zf-RING_2 PF13639.6 KKK21747.1 - 1.8e-05 25.0 4.8 1.8e-05 25.0 4.8 4.0 2 1 1 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.25 KKK21747.1 - 0.00015 21.6 5.1 0.00015 21.6 5.1 4.5 3 1 1 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KKK21747.1 - 0.0032 17.3 6.8 0.0032 17.3 6.8 4.9 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KKK21747.1 - 0.011 15.7 8.5 0.011 15.7 8.5 3.8 2 1 1 3 3 3 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 KKK21747.1 - 0.017 15.2 4.4 0.017 15.2 4.4 3.9 3 1 0 3 3 3 0 RING-type zinc-finger UN_NPL4 PF11543.8 KKK21747.1 - 0.026 15.0 0.0 0.051 14.1 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Trp_syntA PF00290.20 KKK21747.1 - 0.22 10.3 0.0 0.39 9.5 0.0 1.3 1 0 0 1 1 1 0 Tryptophan synthase alpha chain MGDG_synth PF06925.11 KKK21748.1 - 0.096 12.8 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 Monogalactosyldiacylglycerol (MGDG) synthase DUF5487 PF17589.2 KKK21748.1 - 0.84 9.9 2.5 1.1 9.6 0.1 2.3 3 0 0 3 3 3 0 Family of unknown function (DUF5487) Claudin_2 PF13903.6 KKK21749.1 - 0.061 13.1 3.2 0.24 11.1 1.3 2.4 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction Methyltransf_34 PF11312.8 KKK21751.1 - 1.4e-104 349.6 0.0 3e-104 348.6 0.0 1.5 1 1 0 1 1 1 1 Putative SAM-dependent methyltransferase DUF5444 PF17519.2 KKK21751.1 - 0.12 12.4 0.6 0.53 10.3 0.0 2.4 3 0 0 3 3 3 0 Family of unknown function (DUF5444) FAM176 PF14851.6 KKK21751.1 - 5 6.8 5.2 1.1 8.9 0.2 2.2 2 0 0 2 2 2 0 FAM176 family Band_7 PF01145.25 KKK21752.1 - 1.4e-24 87.0 9.2 2e-24 86.6 8.2 1.7 1 1 0 1 1 1 1 SPFH domain / Band 7 family YdfA_immunity PF12127.8 KKK21752.1 - 0.0014 17.8 4.2 0.0018 17.4 4.2 1.2 1 0 0 1 1 1 1 SigmaW regulon antibacterial PknG_rubred PF16919.5 KKK21752.1 - 0.14 12.3 0.2 0.23 11.6 0.2 1.3 1 0 0 1 1 1 0 Protein kinase G rubredoxin domain UcrQ PF02939.16 KKK21753.1 - 7.3e-31 105.9 0.1 8.8e-31 105.7 0.1 1.1 1 0 0 1 1 1 1 UcrQ family Cyt_b-c1_8 PF10890.8 KKK21753.1 - 0.092 13.2 0.0 0.13 12.7 0.0 1.2 1 0 0 1 1 1 0 Cytochrome b-c1 complex subunit 8 PX PF00787.24 KKK21754.1 - 9e-14 51.4 0.0 2.4e-13 50.1 0.0 1.7 2 0 0 2 2 2 1 PX domain DGF-1_C PF11040.8 KKK21754.1 - 0.059 13.4 0.9 0.14 12.2 0.1 2.1 2 0 0 2 2 2 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus UPF0242 PF06785.11 KKK21754.1 - 7.6 6.6 8.8 26 4.8 9.1 1.7 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus SIP1 PF04938.12 KKK21755.1 - 3.6e-10 39.9 0.0 5.2e-08 32.9 0.0 2.7 2 1 0 2 2 2 2 Survival motor neuron (SMN) interacting protein 1 (SIP1) ArfGap PF01412.18 KKK21756.1 - 5.5e-34 116.8 0.1 5.5e-34 116.8 0.1 2.3 3 0 0 3 3 3 1 Putative GTPase activating protein for Arf BAR_3 PF16746.5 KKK21756.1 - 1.4e-15 57.7 12.5 6e-11 42.5 9.6 2.4 1 1 1 2 2 2 2 BAR domain of APPL family PH PF00169.29 KKK21756.1 - 2.9e-12 47.0 0.2 1.3e-11 44.9 0.2 2.2 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 KKK21756.1 - 0.0063 16.9 0.5 0.03 14.7 0.5 2.2 1 0 0 1 1 1 1 Pleckstrin homology domain ATP-cone PF03477.16 KKK21756.1 - 0.02 15.5 1.1 0.063 13.9 1.1 1.8 1 0 0 1 1 1 0 ATP cone domain HEPN_Toprim_N PF18871.1 KKK21756.1 - 0.34 10.8 2.3 0.33 10.9 0.3 1.9 1 1 1 2 2 2 0 HEPN/Toprim N-terminal domain 1 CIA30 PF08547.12 KKK21795.1 - 6.4e-40 136.8 0.0 1.4e-26 93.4 0.0 2.1 2 0 0 2 2 2 2 Complex I intermediate-associated protein 30 (CIA30) Sugar_tr PF00083.24 KKK21796.1 - 1.6e-100 337.1 17.1 1.8e-100 336.9 17.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKK21796.1 - 7.2e-20 71.2 53.6 8.1e-18 64.5 26.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Phage_holin_3_2 PF04550.12 KKK21796.1 - 0.0092 16.5 0.2 0.029 14.9 0.2 1.8 1 0 0 1 1 1 1 Phage holin family 2 YtpI PF14007.6 KKK21796.1 - 1.1 9.5 6.4 0.2 11.8 0.6 2.5 2 0 0 2 2 2 0 YtpI-like protein SAICAR_synt PF01259.18 KKK21797.1 - 6.8e-38 130.7 0.0 8e-38 130.5 0.0 1.1 1 0 0 1 1 1 1 SAICAR synthetase HSP70 PF00012.20 KKK21807.1 - 0.0061 14.8 0.0 0.0091 14.2 0.0 1.1 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KKK21807.1 - 0.054 12.3 0.0 0.12 11.2 0.0 1.5 2 0 0 2 2 2 0 MreB/Mbl protein IMPDH PF00478.25 KKK21807.1 - 0.19 10.7 0.2 1.1 8.2 0.0 1.9 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain Indigoidine_A PF04227.12 KKK21822.1 - 9.7e-115 382.9 0.4 3.5e-113 377.8 0.4 2.3 1 1 0 1 1 1 1 Indigoidine synthase A like protein PfkB PF00294.24 KKK21822.1 - 4.9e-19 68.8 4.3 1.3e-11 44.4 0.2 2.8 2 1 0 2 2 2 2 pfkB family carbohydrate kinase Ribophorin_I PF04597.14 KKK21823.1 - 1.1e-119 400.6 2.2 1.2e-119 400.4 2.2 1.0 1 0 0 1 1 1 1 Ribophorin I DLH PF01738.18 KKK21824.1 - 4.1e-05 23.2 0.0 7.7e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Dienelactone hydrolase family SnoaL PF07366.12 KKK21824.1 - 0.0012 18.6 0.0 0.0017 18.2 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 KKK21824.1 - 0.0033 18.0 0.0 0.0073 16.9 0.0 1.6 1 0 0 1 1 1 1 SnoaL-like domain Mcp5_PH PF12814.7 KKK21828.1 - 1.3e-20 73.7 0.1 2.9e-20 72.6 0.1 1.5 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology Fez1 PF06818.15 KKK21828.1 - 0.00095 19.7 11.1 0.0018 18.7 11.1 1.4 1 0 0 1 1 1 1 Fez1 Macoilin PF09726.9 KKK21828.1 - 0.0016 17.1 0.7 0.0025 16.5 0.7 1.2 1 0 0 1 1 1 1 Macoilin family DUF724 PF05266.14 KKK21828.1 - 0.0021 17.9 3.8 0.0034 17.3 3.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF724) zf-C4H2 PF10146.9 KKK21828.1 - 0.0023 18.3 1.0 0.0023 18.3 1.0 2.8 2 1 0 2 2 1 1 Zinc finger-containing protein TPR_MLP1_2 PF07926.12 KKK21828.1 - 0.0049 16.9 16.1 0.019 15.1 13.9 2.3 1 1 1 2 2 2 1 TPR/MLP1/MLP2-like protein MscS_porin PF12795.7 KKK21828.1 - 0.018 14.6 7.3 0.032 13.8 7.3 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain Lebercilin PF15619.6 KKK21828.1 - 0.029 14.1 13.4 0.05 13.3 13.4 1.3 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease UPF0242 PF06785.11 KKK21828.1 - 0.041 14.0 7.3 0.067 13.3 7.3 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Exonuc_VII_L PF02601.15 KKK21828.1 - 0.1 12.1 5.2 0.17 11.4 5.2 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit GAS PF13851.6 KKK21828.1 - 0.14 11.5 15.8 0.16 11.3 2.5 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding TACC_C PF05010.14 KKK21828.1 - 0.16 11.8 6.1 0.27 11.0 6.1 1.3 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Spore_III_AB PF09548.10 KKK21828.1 - 0.18 11.9 0.9 0.3 11.2 0.9 1.3 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) TMF_DNA_bd PF12329.8 KKK21828.1 - 0.32 11.0 10.1 0.47 10.5 1.4 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Golgin_A5 PF09787.9 KKK21828.1 - 0.62 9.5 11.6 0.99 8.8 11.6 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 CorA PF01544.18 KKK21828.1 - 0.63 9.3 4.1 1 8.6 4.1 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Fib_alpha PF08702.10 KKK21828.1 - 1.4 9.1 4.4 19 5.4 0.6 2.2 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Tropomyosin_1 PF12718.7 KKK21828.1 - 3.5 7.8 15.1 9.8 6.3 14.9 1.8 1 1 0 1 1 1 0 Tropomyosin like BRE1 PF08647.11 KKK21828.1 - 4.4 7.4 10.0 1.8 8.7 2.1 2.3 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase Spc7 PF08317.11 KKK21828.1 - 6.3 5.6 10.3 13 4.6 10.3 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein Atg14 PF10186.9 KKK21828.1 - 7.5 5.5 8.5 14 4.7 8.5 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 ADIP PF11559.8 KKK21828.1 - 9.7 6.3 16.7 0.8 9.8 3.6 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Glyco_hydro_28 PF00295.17 KKK21829.1 - 2.2e-49 168.3 7.7 3.8e-49 167.5 7.6 1.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 28 MPC PF03650.13 KKK21830.1 - 3.7e-39 133.3 0.1 3.8e-33 113.9 0.0 2.2 2 0 0 2 2 2 2 Mitochondrial pyruvate carriers DUF1512 PF07431.12 KKK21830.1 - 0.1 11.6 0.2 0.13 11.2 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1512) Sel1 PF08238.12 KKK21831.1 - 9.9e-38 127.7 42.7 1e-08 35.5 0.1 8.1 8 0 0 8 8 8 7 Sel1 repeat TPR_20 PF14561.6 KKK21831.1 - 0.18 12.1 0.5 1.5 9.2 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat AAA_12 PF13087.6 KKK21832.1 - 3.1e-39 134.7 0.0 5.1e-39 134.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KKK21832.1 - 4.1e-06 26.8 0.0 0.022 14.6 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 KKK21832.1 - 7e-05 23.2 0.0 0.0047 17.3 0.0 3.0 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KKK21832.1 - 0.032 14.0 0.0 1.1 8.9 0.0 2.5 2 1 0 2 2 2 0 AAA domain ATPase PF06745.13 KKK21832.1 - 0.058 12.7 0.0 0.097 12.0 0.0 1.3 1 0 0 1 1 1 0 KaiC Sigma54_activat PF00158.26 KKK21832.1 - 0.16 11.7 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain Viral_helicase1 PF01443.18 KKK21832.1 - 0.24 11.1 0.5 40 3.8 0.0 3.5 4 1 1 5 5 5 0 Viral (Superfamily 1) RNA helicase LigB PF02900.18 KKK21833.1 - 1.8e-34 119.1 0.0 2.3e-34 118.7 0.0 1.1 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase L51_S25_CI-B8 PF05047.16 KKK21834.1 - 9.3e-10 38.3 0.0 1.2e-09 37.9 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain NAT PF04768.13 KKK21835.1 - 4.9e-56 189.0 0.1 1.1e-55 187.9 0.0 1.6 2 0 0 2 2 2 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase Semialdhyde_dh PF01118.24 KKK21835.1 - 6.9e-31 107.2 0.0 1.8e-30 105.8 0.0 1.8 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain AA_kinase PF00696.28 KKK21835.1 - 6.7e-29 101.2 0.0 1.5e-28 100.1 0.0 1.5 1 0 0 1 1 1 1 Amino acid kinase family DapB_N PF01113.20 KKK21835.1 - 0.078 13.1 0.0 0.26 11.4 0.0 2.0 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Synaptobrevin PF00957.21 KKK21836.1 - 4.9e-31 106.4 0.4 5.8e-31 106.1 0.4 1.1 1 0 0 1 1 1 1 Synaptobrevin Prominin PF05478.11 KKK21836.1 - 0.01 13.8 0.1 0.013 13.5 0.1 1.1 1 0 0 1 1 1 0 Prominin Cation_ATPase_C PF00689.21 KKK21836.1 - 0.037 13.7 0.1 0.048 13.4 0.1 1.1 1 0 0 1 1 1 0 Cation transporting ATPase, C-terminus SNARE PF05739.19 KKK21836.1 - 4.6 7.3 7.9 1.6 8.8 3.5 2.2 2 0 0 2 2 2 0 SNARE domain Ank_2 PF12796.7 KKK21837.1 - 5.5e-144 469.1 3.8 3e-18 66.2 0.0 12.2 2 2 9 12 12 12 12 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KKK21837.1 - 2.8e-108 353.0 0.1 4.2e-12 46.3 0.0 16.1 5 2 11 18 18 18 18 Ankyrin repeats (many copies) Ank_3 PF13606.6 KKK21837.1 - 1.3e-97 307.9 0.1 0.00012 22.2 0.0 23.1 23 0 0 23 23 23 22 Ankyrin repeat Ank PF00023.30 KKK21837.1 - 6.1e-97 314.2 1.2 0.00028 21.2 0.0 22.9 23 0 0 23 23 23 22 Ankyrin repeat Ank_5 PF13857.6 KKK21837.1 - 2e-93 305.2 12.9 3.8e-10 39.8 0.0 17.3 6 2 11 18 18 18 18 Ankyrin repeats (many copies) VWA_3_C PF18571.1 KKK21837.1 - 0.038 13.9 0.6 1.3e+02 2.6 0.0 6.2 7 0 0 7 7 7 0 von Willebrand factor type A C-terminal domain DUF3718 PF12514.8 KKK21837.1 - 0.16 12.1 0.2 3.2 8.0 0.0 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF3718) CBP4 PF07960.11 KKK21838.1 - 1.7e-30 105.5 5.4 3.7e-30 104.4 5.4 1.4 1 1 0 1 1 1 1 CBP4 HNH_2 PF13391.6 KKK21858.1 - 6.6e-05 23.0 0.0 0.0002 21.5 0.0 1.8 2 0 0 2 2 2 1 HNH endonuclease Fumble PF03630.14 KKK21859.1 - 3.4e-145 483.4 1.3 4.2e-145 483.1 1.3 1.1 1 0 0 1 1 1 1 Fumble DEAD PF00270.29 KKK21860.1 - 4.1e-45 153.7 0.0 1.3e-44 152.0 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KKK21860.1 - 5.4e-27 94.3 0.0 3.3e-26 91.8 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KKK21860.1 - 0.0082 16.2 0.0 0.016 15.2 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UTP25 PF06862.12 KKK21860.1 - 0.076 11.8 0.1 2.9 6.6 0.0 2.7 3 0 0 3 3 3 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Polysacc_deac_1 PF01522.21 KKK21861.1 - 2.4e-19 69.5 0.0 3.8e-19 68.8 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.9 KKK21861.1 - 0.00062 19.5 0.0 0.0013 18.4 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) SIR2 PF02146.17 KKK21861.1 - 0.2 11.6 0.0 0.33 10.8 0.0 1.3 1 0 0 1 1 1 0 Sir2 family Metallophos PF00149.28 KKK21862.1 - 4.7e-17 63.2 0.4 7.8e-17 62.5 0.4 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KKK21862.1 - 0.0001 22.5 0.0 0.0014 18.9 0.0 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain FMN_dh PF01070.18 KKK21863.1 - 5.7e-121 403.8 0.0 6.6e-121 403.6 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 KKK21863.1 - 3e-06 26.5 0.5 7.1e-05 22.0 0.1 2.1 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 KKK21863.1 - 0.00021 20.6 0.1 0.00032 19.9 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase DHO_dh PF01180.21 KKK21863.1 - 0.021 14.1 0.0 0.032 13.4 0.0 1.3 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase His_biosynth PF00977.21 KKK21863.1 - 0.11 11.9 0.0 0.48 9.9 0.0 2.0 1 1 0 1 1 1 0 Histidine biosynthesis protein Aldolase_II PF00596.21 KKK21864.1 - 2.5e-49 167.7 0.2 3.1e-49 167.4 0.2 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Fungal_trans_2 PF11951.8 KKK21865.1 - 4e-61 207.0 5.1 5.5e-61 206.5 5.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK21865.1 - 7.9e-10 38.7 6.0 1.7e-09 37.6 6.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldedh PF00171.22 KKK21866.1 - 3.4e-125 418.2 4.1 3.8e-125 418.0 4.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family HAD PF12710.7 KKK21867.1 - 1.7e-22 80.7 0.0 2.2e-22 80.4 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase UMPH-1 PF05822.12 KKK21867.1 - 0.054 13.0 0.0 0.19 11.2 0.0 1.8 1 1 0 1 1 1 0 Pyrimidine 5'-nucleotidase (UMPH-1) DUF1574 PF07611.11 KKK21867.1 - 0.067 12.5 0.0 0.087 12.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1574) GCD14 PF08704.10 KKK21868.1 - 5.4e-06 26.3 0.3 0.018 14.7 0.0 2.5 3 0 0 3 3 3 2 tRNA methyltransferase complex GCD14 subunit GCD14_N PF14801.6 KKK21868.1 - 0.00011 22.0 0.3 0.0002 21.1 0.3 1.4 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit N-term Methyltransf_25 PF13649.6 KKK21868.1 - 0.1 13.3 0.1 20 6.0 0.0 2.5 2 0 0 2 2 2 0 Methyltransferase domain 4HBT_2 PF13279.6 KKK21869.1 - 1.3e-26 93.5 0.1 2e-26 92.8 0.1 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.22 KKK21869.1 - 9.4e-06 25.9 0.0 1.8e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily Methyltransf_25 PF13649.6 KKK21870.1 - 7.5e-10 39.4 0.0 1.4e-09 38.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KKK21870.1 - 7.7e-07 29.7 0.0 1.4e-06 28.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KKK21870.1 - 0.0018 17.7 0.0 0.0028 17.0 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 KKK21870.1 - 0.0075 16.1 0.0 0.014 15.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Complex1_LYR_2 PF13233.6 KKK21871.1 - 0.0036 18.0 0.0 0.0036 18.0 0.0 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 KKK21871.1 - 0.0064 16.5 0.2 0.011 15.8 0.2 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) DUF4646 PF15496.6 KKK21872.1 - 0.035 14.7 1.1 0.58 10.8 1.1 2.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4646) CAF-1_p150 PF11600.8 KKK21872.1 - 0.74 9.5 21.1 0.11 12.1 14.6 2.2 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Acetyltransf_1 PF00583.25 KKK21873.1 - 3.1e-10 40.3 0.0 4.6e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KKK21873.1 - 1.2e-07 31.7 0.1 1.7e-07 31.2 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KKK21873.1 - 1.5e-07 31.3 0.0 2.5e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 KKK21873.1 - 5.6e-05 23.5 0.0 8.8e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KKK21873.1 - 0.0088 16.1 0.2 0.017 15.2 0.2 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Pkinase PF00069.25 KKK21874.1 - 6.3e-12 45.4 0.0 1.3e-11 44.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK21874.1 - 1.7e-06 27.6 0.0 3.1e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT PF02985.22 KKK21874.1 - 5.8e-06 26.1 0.5 0.24 11.7 0.0 4.8 4 0 0 4 4 4 2 HEAT repeat Cnd1 PF12717.7 KKK21874.1 - 1.9e-05 24.7 0.0 7.6e-05 22.8 0.0 1.9 1 1 1 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 KKK21874.1 - 0.00067 20.1 0.4 1.8 9.2 0.0 3.1 2 1 0 2 2 2 2 HEAT-like repeat HEAT_2 PF13646.6 KKK21874.1 - 0.0074 16.7 0.1 0.2 12.0 0.1 2.9 1 1 2 3 3 3 2 HEAT repeats Kinase-like PF14531.6 KKK21874.1 - 0.1 11.9 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Kinase-like LsmAD PF06741.13 KKK21875.1 - 1.5e-28 99.2 3.5 1.5e-28 99.2 3.5 2.0 2 0 0 2 2 2 1 LsmAD domain SM-ATX PF14438.6 KKK21875.1 - 7e-20 71.0 0.0 1.3e-19 70.1 0.0 1.5 1 0 0 1 1 1 1 Ataxin 2 SM domain AIP3 PF03915.13 KKK21876.1 - 5e-153 510.0 4.0 1.1e-152 508.8 4.0 1.6 1 0 0 1 1 1 1 Actin interacting protein 3 Lectin_N PF03954.14 KKK21876.1 - 0.0036 17.0 1.8 0.0097 15.7 0.5 2.4 1 1 1 2 2 2 1 Hepatic lectin, N-terminal domain RasGAP_C PF03836.15 KKK21876.1 - 0.036 14.2 2.0 0.27 11.4 0.6 3.2 4 1 1 5 5 5 0 RasGAP C-terminus ATG_C PF09333.11 KKK21876.1 - 0.084 13.2 0.4 1.4 9.3 0.1 3.0 3 0 0 3 3 3 0 Autophagy-related protein C terminal domain DUF4407 PF14362.6 KKK21876.1 - 0.13 11.6 0.0 0.13 11.6 0.0 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4407) Syntaxin_2 PF14523.6 KKK21876.1 - 1.1 9.7 4.8 5 7.6 0.1 3.1 2 1 0 2 2 2 0 Syntaxin-like protein Pkinase PF00069.25 KKK21877.1 - 1.2e-15 57.6 0.0 2.1e-15 56.8 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK21877.1 - 0.091 12.0 0.0 0.17 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein tyrosine kinase DbpA PF03880.15 KKK21878.1 - 0.018 15.0 0.0 0.037 14.0 0.0 1.5 1 0 0 1 1 1 0 DbpA RNA binding domain Peptidase_S49_N PF08496.10 KKK21879.1 - 6.2 6.9 8.8 5.6 7.0 4.6 2.1 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Beta_elim_lyase PF01212.21 KKK21880.1 - 2.5e-69 233.8 0.0 2.9e-69 233.6 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase OKR_DC_1 PF01276.20 KKK21880.1 - 0.0017 17.1 0.0 0.0026 16.6 0.0 1.1 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain Yippee-Mis18 PF03226.14 KKK21881.1 - 0.19 11.9 1.7 0.41 10.9 1.7 1.5 1 0 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DUF2703 PF10865.8 KKK21881.1 - 0.22 11.7 3.8 0.19 11.9 0.2 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF2703) Glyco_transf_34 PF05637.12 KKK21882.1 - 5.5e-16 59.0 0.2 6.9e-16 58.7 0.2 1.1 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family PgaD PF13994.6 KKK21882.1 - 0.076 13.1 1.9 0.1 12.6 1.5 1.5 1 1 1 2 2 2 0 PgaD-like protein Pkinase PF00069.25 KKK21883.1 - 2e-67 227.3 0.0 4.7e-67 226.1 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK21883.1 - 4.7e-32 111.3 0.0 7.6e-32 110.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 KKK21883.1 - 5.1e-10 39.6 1.2 1.4e-09 38.2 0.2 2.4 3 0 0 3 3 3 1 FHA domain Yop-YscD_cpl PF16697.5 KKK21883.1 - 0.0016 18.7 0.0 0.004 17.4 0.0 1.6 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Kdo PF06293.14 KKK21883.1 - 0.0029 17.0 0.1 0.0051 16.2 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KKK21883.1 - 0.0097 15.2 0.0 0.023 14.0 0.0 1.6 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 KKK21883.1 - 0.0099 15.8 0.1 5 7.0 0.1 3.0 2 1 1 3 3 3 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KKK21883.1 - 0.021 13.6 0.0 0.041 12.6 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase RNase_T PF00929.24 KKK21884.1 - 2.8e-10 41.0 0.0 1.2e-09 39.0 0.0 1.9 1 1 0 1 1 1 1 Exonuclease Ribosomal_60s PF00428.19 KKK21884.1 - 4.2 8.0 15.2 1.3e+02 3.3 0.0 2.9 3 0 0 3 3 3 0 60s Acidic ribosomal protein Glutaredoxin PF00462.24 KKK21885.1 - 1e-18 67.2 0.0 8.2e-17 61.2 0.0 2.6 3 1 0 3 3 3 1 Glutaredoxin Thioredoxin PF00085.20 KKK21885.1 - 8.8e-14 51.4 0.0 2.4e-13 50.0 0.0 1.7 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_8 PF13905.6 KKK21885.1 - 0.00024 21.4 0.0 0.0014 18.9 0.0 2.1 1 1 1 2 2 2 1 Thioredoxin-like HyaE PF07449.11 KKK21885.1 - 0.081 12.9 0.0 0.39 10.7 0.0 2.1 3 0 0 3 3 3 0 Hydrogenase-1 expression protein HyaE Thioredoxin_2 PF13098.6 KKK21885.1 - 0.14 12.6 0.2 0.98 9.9 0.1 2.5 2 2 0 2 2 2 0 Thioredoxin-like domain TraF PF13728.6 KKK21885.1 - 0.16 11.8 0.1 4.2 7.1 0.1 2.1 2 0 0 2 2 2 0 F plasmid transfer operon protein HNH_2 PF13391.6 KKK21886.1 - 9.8e-14 51.3 0.0 2.9e-13 49.8 0.0 1.8 2 0 0 2 2 2 1 HNH endonuclease HATPase_c_3 PF13589.6 KKK21887.1 - 3.3e-21 75.6 0.0 5.3e-21 74.9 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MutL_C PF08676.11 KKK21887.1 - 6.4e-09 35.7 0.0 3.3e-08 33.4 0.0 2.0 2 0 0 2 2 2 1 MutL C terminal dimerisation domain HATPase_c PF02518.26 KKK21887.1 - 0.0039 17.7 0.0 0.0098 16.4 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Lipoprotein_21 PF14041.6 KKK21887.1 - 0.11 12.7 0.0 0.3 11.2 0.0 1.7 1 0 0 1 1 1 0 LppP/LprE lipoprotein DUF2834 PF11196.8 KKK21889.1 - 0.14 12.6 1.1 0.25 11.7 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2834) NAD_binding_8 PF13450.6 KKK21890.1 - 7.9e-14 51.6 0.0 1.9e-13 50.4 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 KKK21890.1 - 3.5e-05 23.3 0.1 0.0001 21.8 0.0 1.7 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase DAO PF01266.24 KKK21890.1 - 0.00011 21.9 0.1 0.063 12.8 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KKK21890.1 - 0.00014 21.2 0.1 0.49 9.6 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KKK21890.1 - 0.028 13.5 0.0 0.042 12.9 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.6 KKK21890.1 - 0.066 13.2 0.2 2 8.4 0.0 2.7 2 0 0 2 2 2 0 FAD-NAD(P)-binding tRNA-synt_2 PF00152.20 KKK21897.1 - 7e-67 225.7 0.0 8.2e-67 225.5 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.20 KKK21897.1 - 1.4e-07 31.2 0.1 0.00013 21.6 0.0 2.4 3 0 0 3 3 3 2 tRNA synthetases class II core domain (F) tRNA_anti-codon PF01336.25 KKK21897.1 - 0.0026 17.7 0.0 0.0049 16.8 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain 2OG-FeII_Oxy PF03171.20 KKK21898.1 - 0.00024 21.5 0.0 0.00044 20.7 0.0 1.6 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Clr2 PF10383.9 KKK21899.1 - 6.2e-31 108.1 0.0 1.1e-30 107.3 0.0 1.4 1 0 0 1 1 1 1 Transcription-silencing protein Clr2 DUF3319 PF11782.8 KKK21899.1 - 0.1 12.6 0.0 0.34 10.9 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3319) ABC_membrane_2 PF06472.15 KKK21900.1 - 1.5e-86 290.1 0.0 3.2e-86 289.1 0.0 1.5 2 0 0 2 2 2 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 KKK21900.1 - 1.1e-12 48.6 0.0 2.5e-12 47.5 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_23 PF13476.6 KKK21900.1 - 0.0016 19.0 1.5 0.81 10.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain RuvB_N PF05496.12 KKK21900.1 - 0.018 14.8 0.0 0.059 13.1 0.0 1.8 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KKK21900.1 - 0.06 13.7 0.1 0.15 12.5 0.1 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 KKK21900.1 - 0.065 13.7 0.0 0.16 12.4 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 KKK21900.1 - 0.076 12.8 0.0 0.26 11.1 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain Mg_chelatase PF01078.21 KKK21900.1 - 0.17 11.3 0.0 0.27 10.6 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DUF2459 PF09601.10 KKK21910.1 - 0.13 12.1 0.4 0.25 11.1 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2459) IU_nuc_hydro PF01156.19 KKK21911.1 - 1.3e-37 130.0 0.0 1.6e-37 129.7 0.0 1.1 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Glyco_hydro_16 PF00722.21 KKK21912.1 - 2.4e-43 147.7 5.3 2.4e-43 147.7 5.3 2.3 3 0 0 3 3 3 1 Glycosyl hydrolases family 16 SNF2_N PF00176.23 KKK21913.1 - 1.1e-65 221.7 0.5 2e-65 220.8 0.5 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KKK21913.1 - 3.3e-16 59.6 0.0 2.7e-15 56.6 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KKK21913.1 - 6.2e-10 39.3 0.2 3.6e-08 33.6 0.0 2.7 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit zf-C3HC4_2 PF13923.6 KKK21913.1 - 8.1e-09 35.2 2.2 8.1e-09 35.2 2.2 1.9 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KKK21913.1 - 2.4e-08 33.7 2.3 5.9e-08 32.4 2.3 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KKK21913.1 - 2e-07 30.9 3.6 5e-07 29.6 3.6 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 KKK21913.1 - 1.5e-06 28.4 4.6 4.1e-06 27.0 4.6 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KKK21913.1 - 5e-06 26.3 3.9 1.3e-05 25.0 3.9 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KKK21913.1 - 1.7e-05 24.7 3.0 1.7e-05 24.7 3.0 1.9 2 0 0 2 2 1 1 zinc-RING finger domain DEAD PF00270.29 KKK21913.1 - 2.1e-05 24.3 0.1 0.0002 21.2 0.0 2.4 2 1 0 2 2 2 1 DEAD/DEAH box helicase zf-C3HC4_4 PF15227.6 KKK21913.1 - 0.00062 19.9 6.0 0.0015 18.6 6.0 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 KKK21913.1 - 0.00064 19.5 4.9 0.0015 18.3 4.9 1.6 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_14 PF17978.1 KKK21913.1 - 0.012 16.0 0.7 0.033 14.6 0.7 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_11 PF17123.5 KKK21913.1 - 0.026 14.2 1.2 0.067 13.0 1.2 1.7 1 0 0 1 1 1 0 RING-like zinc finger AAA_34 PF13872.6 KKK21913.1 - 0.033 13.1 0.0 0.062 12.2 0.0 1.3 1 0 0 1 1 1 0 P-loop containing NTP hydrolase pore-1 Prok-RING_4 PF14447.6 KKK21913.1 - 0.054 13.4 7.4 0.18 11.7 5.9 2.6 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 YL1 PF05764.13 KKK21913.1 - 0.35 11.0 24.0 0.024 14.8 13.2 2.3 2 0 0 2 2 2 0 YL1 nuclear protein DZR PF12773.7 KKK21913.1 - 0.62 10.1 3.2 1.3 9.1 3.2 1.6 1 0 0 1 1 1 0 Double zinc ribbon TLP-20 PF06088.11 KKK21913.1 - 5.5 6.9 6.8 15 5.5 6.8 1.7 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Ras PF00071.22 KKK21914.1 - 1.8e-41 141.4 0.0 2.4e-41 141.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KKK21914.1 - 4.6e-22 78.5 0.0 1.3e-21 77.0 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKK21914.1 - 5.5e-06 26.0 0.1 7.7e-06 25.5 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Nas2_N PF18265.1 KKK21915.1 - 1.1e-26 92.6 0.1 1.7e-26 91.9 0.1 1.3 1 0 0 1 1 1 1 Nas2 N_terminal domain PDZ_6 PF17820.1 KKK21915.1 - 8.9e-11 41.5 0.1 1.4e-10 40.8 0.1 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KKK21915.1 - 5.3e-08 33.1 0.0 1.3e-07 31.9 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 KKK21915.1 - 1.3e-05 25.4 0.0 2.3e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 PDZ domain GRASP55_65 PF04495.14 KKK21915.1 - 7.4e-05 23.1 0.0 0.00011 22.5 0.0 1.4 1 0 0 1 1 1 1 GRASP55/65 PDZ-like domain HMA PF00403.26 KKK21915.1 - 0.02 15.3 0.0 0.058 13.9 0.0 1.7 1 0 0 1 1 1 0 Heavy-metal-associated domain RhoGEF PF00621.20 KKK21916.1 - 2e-20 73.8 0.5 3.8e-20 72.9 0.5 1.5 1 0 0 1 1 1 1 RhoGEF domain Ran_BP1 PF00638.18 KKK21917.1 - 7.9e-14 52.0 0.0 1.5e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 RanBP1 domain NUP50 PF08911.11 KKK21917.1 - 0.00014 22.4 2.2 0.00014 22.4 2.2 7.8 8 0 0 8 8 8 1 NUP50 (Nucleoporin 50 kDa) U79_P34 PF03064.16 KKK21917.1 - 0.2 11.0 5.9 0.38 10.1 5.9 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 SCP2 PF02036.17 KKK21918.1 - 2.4e-24 85.7 0.4 3.1e-24 85.4 0.4 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 KKK21918.1 - 1.1e-08 35.4 0.1 1.3e-08 35.1 0.1 1.1 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal SCP2_2 PF13530.6 KKK21918.1 - 0.027 14.9 0.0 0.034 14.5 0.0 1.3 1 0 0 1 1 1 0 Sterol carrier protein domain UDG PF03167.19 KKK21919.1 - 3.7e-21 75.7 0.0 5.3e-21 75.2 0.0 1.2 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Sporozoite_P67 PF05642.11 KKK21919.1 - 0.014 13.6 1.7 0.017 13.2 1.7 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen XRCC4 PF06632.12 KKK21919.1 - 0.56 9.0 2.2 0.74 8.6 2.2 1.1 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 SBDS PF01172.18 KKK21920.1 - 2e-23 82.2 0.0 2.3e-23 82.0 0.0 1.0 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein NB-ARC PF00931.22 KKK21920.1 - 0.1 11.8 0.0 0.11 11.7 0.0 1.1 1 0 0 1 1 1 0 NB-ARC domain Phage_TAC_5 PF08890.11 KKK21920.1 - 0.12 12.4 0.0 0.59 10.1 0.0 1.8 2 0 0 2 2 2 0 Phage XkdN-like tail assembly chaperone protein, TAC AAA_7 PF12775.7 KKK21920.1 - 0.22 11.0 0.2 0.44 10.0 0.1 1.5 2 0 0 2 2 2 0 P-loop containing dynein motor region Cu-oxidase_3 PF07732.15 KKK21921.1 - 1.5e-39 134.7 0.9 4.1e-38 130.0 0.0 2.8 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 KKK21921.1 - 4.6e-32 110.6 3.6 3e-30 104.7 0.1 3.2 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.22 KKK21921.1 - 5.1e-14 52.7 0.0 3.2e-13 50.1 0.0 2.2 2 0 0 2 2 2 1 Multicopper oxidase PhyH PF05721.13 KKK21922.1 - 3.2e-09 37.4 0.0 5.5e-09 36.6 0.0 1.4 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.12 KKK21922.1 - 6.1e-09 35.1 0.1 0.015 14.1 0.1 3.1 3 0 0 3 3 3 3 Protein of unknown function (DUF1479) Peptidase_S10 PF00450.22 KKK21923.1 - 2.1e-77 261.3 0.0 2.8e-77 260.9 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Phosphoesterase PF04185.14 KKK21924.1 - 3.2e-74 250.3 4.1 4.3e-74 249.8 4.1 1.1 1 0 0 1 1 1 1 Phosphoesterase family Sugar_tr PF00083.24 KKK21925.1 - 1.2e-40 139.7 18.7 2.2e-21 76.2 8.4 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KKK21925.1 - 1.6e-25 89.8 23.8 1.4e-18 67.0 13.6 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily UPF0542 PF15086.6 KKK21925.1 - 0.18 11.8 0.0 0.37 10.7 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family UPF0542 Peptidase_S10 PF00450.22 KKK21926.1 - 2.2e-91 307.4 1.8 4.8e-91 306.2 1.8 1.5 1 1 0 1 1 1 1 Serine carboxypeptidase Fungal_trans_2 PF11951.8 KKK21927.1 - 6.3e-51 173.4 0.2 8.6e-51 172.9 0.2 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK21927.1 - 2.3e-12 46.8 25.6 1.7e-06 28.0 6.9 2.4 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Hexokinase_2 PF03727.16 KKK21930.1 - 5.9e-64 215.8 0.0 3.5e-47 160.8 0.0 2.2 2 0 0 2 2 2 2 Hexokinase Hexokinase_1 PF00349.21 KKK21930.1 - 1.7e-61 207.6 0.0 2.5e-61 207.1 0.0 1.3 1 0 0 1 1 1 1 Hexokinase AA_permease_2 PF13520.6 KKK21931.1 - 2.1e-56 191.6 56.1 2.6e-56 191.3 56.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KKK21931.1 - 1.7e-21 76.4 45.8 2.3e-21 76.0 45.8 1.0 1 0 0 1 1 1 1 Amino acid permease Catalase PF00199.19 KKK21932.1 - 2.9e-173 576.4 0.0 3.4e-173 576.1 0.0 1.0 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 KKK21932.1 - 1.2e-13 51.0 0.0 2.7e-13 49.9 0.0 1.6 1 0 0 1 1 1 1 Catalase-related immune-responsive GMC_oxred_N PF00732.19 KKK21933.1 - 3e-55 187.7 0.0 3.9e-55 187.3 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KKK21933.1 - 2.6e-34 118.8 0.0 4e-34 118.2 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KKK21933.1 - 1.7e-05 24.1 1.1 0.046 12.8 0.8 2.2 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.17 KKK21933.1 - 9.6e-05 21.7 0.3 0.0004 19.7 0.1 1.9 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.6 KKK21933.1 - 0.0026 17.9 0.2 0.028 14.6 0.3 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KKK21933.1 - 0.0026 16.8 0.2 0.0063 15.6 0.1 1.6 2 0 0 2 2 2 1 Lycopene cyclase protein DAO PF01266.24 KKK21933.1 - 0.0031 17.2 0.5 0.0069 16.0 0.5 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KKK21933.1 - 0.015 14.6 0.0 0.034 13.4 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KKK21933.1 - 0.18 11.0 0.6 22 4.2 0.5 2.4 2 1 1 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase FMN_dh PF01070.18 KKK21934.1 - 3.7e-105 351.8 0.0 5.9e-105 351.1 0.0 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 KKK21934.1 - 2e-22 79.1 0.0 5e-22 77.8 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain IMPDH PF00478.25 KKK21934.1 - 9.6e-06 24.8 0.6 2e-05 23.7 0.4 1.6 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 KKK21934.1 - 4.8e-05 22.7 0.1 7.8e-05 22.0 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.15 KKK21934.1 - 0.0014 18.1 0.1 0.0026 17.2 0.1 1.4 1 0 0 1 1 1 1 Nitronate monooxygenase DHO_dh PF01180.21 KKK21934.1 - 0.06 12.5 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase His_biosynth PF00977.21 KKK21934.1 - 0.092 12.2 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Histidine biosynthesis protein Ribul_P_3_epim PF00834.19 KKK21934.1 - 0.22 10.9 0.0 0.33 10.3 0.0 1.2 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family MFS_1 PF07690.16 KKK21935.1 - 9.5e-30 103.7 33.4 9.5e-30 103.7 33.4 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 KKK21935.1 - 3.7e-07 29.8 6.1 3.7e-07 29.8 6.1 2.2 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB DUF4064 PF13273.6 KKK21935.1 - 0.53 10.6 8.2 1 9.7 0.7 4.1 3 2 1 4 4 4 0 Protein of unknown function (DUF4064) DIOX_N PF14226.6 KKK21936.1 - 3.7e-18 66.4 0.0 6.2e-18 65.7 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KKK21936.1 - 2.4e-16 60.1 0.0 3.8e-16 59.4 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Fungal_trans PF04082.18 KKK21937.1 - 3.6e-09 36.0 0.0 2.8e-08 33.1 0.0 2.3 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK21937.1 - 0.0017 18.5 14.3 0.0017 18.5 14.3 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glucosamine_iso PF01182.20 KKK21938.1 - 8.1e-20 71.7 0.0 1.3e-19 70.9 0.0 1.3 1 1 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Sugar-bind PF04198.13 KKK21938.1 - 0.03 13.5 0.1 0.045 12.9 0.1 1.3 1 0 0 1 1 1 0 Putative sugar-binding domain Zn_clus PF00172.18 KKK21939.1 - 5.9e-06 26.3 8.8 1.1e-05 25.5 8.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Abhydrolase_3 PF07859.13 KKK21941.1 - 2.3e-09 37.4 0.0 3.2e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KKK21941.1 - 1.4e-08 34.1 0.2 6.4e-08 31.9 0.2 1.8 1 1 0 1 1 1 1 Carboxylesterase family Chlorophyllase2 PF12740.7 KKK21941.1 - 7.3e-06 25.1 0.0 1.1e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Say1_Mug180 PF10340.9 KKK21941.1 - 3.6e-05 22.8 0.0 5.5e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase Abhydrolase_6 PF12697.7 KKK21941.1 - 0.00027 21.6 0.1 0.00045 20.9 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase PF07224.11 KKK21941.1 - 0.0003 19.9 0.0 0.00042 19.4 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase Romo1 PF10247.9 KKK21942.1 - 0.0044 17.4 0.2 0.0099 16.2 0.2 1.5 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 SKG6 PF08693.10 KKK21942.1 - 0.026 13.9 3.7 0.05 13.0 3.7 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain LapA_dom PF06305.11 KKK21942.1 - 0.054 13.3 0.5 0.054 13.3 0.5 1.8 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Gram_pos_anchor PF00746.21 KKK21942.1 - 0.88 9.6 3.1 2.1 8.3 3.1 1.7 1 0 0 1 1 1 0 LPXTG cell wall anchor motif NAGLU PF05089.12 KKK21943.1 - 3.8e-137 456.7 8.0 4.9e-137 456.3 8.0 1.1 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain NAGLU_C PF12972.7 KKK21943.1 - 4.1e-75 252.8 2.8 6.4e-75 252.1 2.8 1.3 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain NAGLU_N PF12971.7 KKK21943.1 - 3.3e-16 58.8 0.0 7.7e-16 57.7 0.0 1.7 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain FYVE PF01363.21 KKK21944.1 - 1.7e-22 79.4 23.1 3.2e-16 59.2 6.1 3.0 3 0 0 3 3 3 2 FYVE zinc finger Rbsn PF11464.8 KKK21944.1 - 5.5e-18 64.4 1.0 1.5e-17 63.0 1.0 1.8 1 0 0 1 1 1 1 Rabenosyn Rab binding domain YqaH PF17448.2 KKK21944.1 - 0.00034 20.9 0.2 0.001 19.3 0.2 1.8 1 0 0 1 1 1 1 Uncharacterized YqaH-like zf-AN1 PF01428.16 KKK21944.1 - 0.0021 18.2 6.1 0.0021 18.2 6.1 3.8 3 1 1 4 4 4 1 AN1-like Zinc finger zf-Di19 PF05605.12 KKK21944.1 - 0.027 14.8 13.3 0.11 12.8 0.1 3.0 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding Flagellin_N PF00669.20 KKK21944.1 - 0.034 14.3 0.5 0.29 11.2 0.0 2.5 2 0 0 2 2 2 0 Bacterial flagellin N-terminal helical region TMF_TATA_bd PF12325.8 KKK21944.1 - 0.05 13.8 0.2 0.05 13.8 0.2 2.7 4 0 0 4 4 4 0 TATA element modulatory factor 1 TATA binding zf-C2H2_4 PF13894.6 KKK21944.1 - 0.33 11.9 0.0 0.33 11.9 0.0 5.1 5 1 0 5 5 5 0 C2H2-type zinc finger UBZ_FAAP20 PF15750.5 KKK21944.1 - 2 8.4 4.8 13 5.9 0.7 3.1 3 0 0 3 3 3 0 Ubiquitin-binding zinc-finger IBR PF01485.21 KKK21944.1 - 2.8 8.2 19.4 0.14 12.4 3.7 3.4 4 0 0 4 4 3 0 IBR domain, a half RING-finger domain HypA PF01155.19 KKK21944.1 - 7.7 6.6 15.2 0.31 11.1 0.5 3.7 3 1 1 4 4 4 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA E1-E2_ATPase PF00122.20 KKK21945.1 - 3.7e-18 65.7 0.0 8.9e-18 64.4 0.0 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 KKK21945.1 - 6.1e-14 52.8 2.6 1.4e-07 32.0 1.7 3.3 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KKK21945.1 - 0.0021 18.1 0.0 0.072 13.2 0.0 2.5 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KKK21945.1 - 0.014 15.2 0.1 0.062 13.0 0.0 2.0 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase S6PP PF05116.13 KKK21945.1 - 0.059 12.9 0.3 0.3 10.6 0.0 2.2 3 0 0 3 3 3 0 Sucrose-6F-phosphate phosphohydrolase SAGA-Tad1 PF12767.7 KKK21947.1 - 1.5e-60 204.9 0.0 2e-60 204.5 0.0 1.2 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit PRP1_N PF06424.12 KKK21948.1 - 3.5e-52 176.7 7.2 8.7e-52 175.5 7.2 1.7 1 0 0 1 1 1 1 PRP1 splicing factor, N-terminal TPR_19 PF14559.6 KKK21948.1 - 9.6e-26 90.1 12.6 5.5e-07 30.0 0.5 9.4 7 2 2 9 9 9 5 Tetratricopeptide repeat TPR_14 PF13428.6 KKK21948.1 - 5.6e-24 82.8 42.0 1.2e-05 25.7 0.2 13.7 7 5 8 15 15 14 8 Tetratricopeptide repeat TPR_11 PF13414.6 KKK21948.1 - 7.1e-09 35.2 7.8 0.4 10.4 0.0 7.8 6 2 2 8 8 8 2 TPR repeat TPR_16 PF13432.6 KKK21948.1 - 1.1e-08 35.5 30.1 0.0055 17.3 0.0 7.8 7 2 1 8 8 7 3 Tetratricopeptide repeat TPR_2 PF07719.17 KKK21948.1 - 1.3e-08 34.3 18.0 1 9.6 0.0 9.2 11 0 0 11 11 9 3 Tetratricopeptide repeat TPR_8 PF13181.6 KKK21948.1 - 2.3e-07 30.5 0.3 2.7 8.4 0.0 6.0 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.28 KKK21948.1 - 1.5e-06 27.8 1.7 0.34 10.8 0.0 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 KKK21948.1 - 1e-05 25.5 10.1 11 6.7 0.1 8.2 9 0 0 9 9 7 0 Tetratricopeptide repeat TPR_12 PF13424.6 KKK21948.1 - 0.0029 17.8 2.3 3.4 8.0 0.0 6.0 5 1 1 6 6 6 1 Tetratricopeptide repeat ZNRF_3_ecto PF18212.1 KKK21948.1 - 0.064 13.3 0.2 25 4.9 0.0 4.4 6 1 0 6 6 6 0 ZNRF-3 Ectodomain DUF3808 PF10300.9 KKK21948.1 - 0.072 11.8 0.2 11 4.6 0.0 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF3808) TPR_21 PF09976.9 KKK21948.1 - 0.098 12.4 18.3 0.44 10.2 2.2 4.5 3 1 1 4 4 4 0 Tetratricopeptide repeat-like domain TPR_7 PF13176.6 KKK21948.1 - 0.11 12.6 0.6 40 4.5 0.0 4.6 5 0 0 5 5 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KKK21948.1 - 0.13 12.5 0.9 26 5.2 0.0 3.9 3 1 2 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 NARP1 PF12569.8 KKK21948.1 - 0.2 10.5 8.5 1.3 7.8 0.0 4.5 4 1 2 6 6 6 0 NMDA receptor-regulated protein 1 Ribosomal_60s PF00428.19 KKK21948.1 - 3.7 8.2 6.9 1.8 9.2 2.3 2.9 3 0 0 3 3 2 0 60s Acidic ribosomal protein RabGAP-TBC PF00566.18 KKK21949.1 - 2.3e-51 174.5 0.0 5.8e-51 173.2 0.0 1.6 1 1 0 1 1 1 1 Rab-GTPase-TBC domain RRM_1 PF00076.22 KKK21950.1 - 6.5e-35 118.8 0.1 2.3e-16 59.3 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KKK21950.1 - 2.6e-11 43.5 0.2 7.7e-05 22.7 0.0 2.8 2 1 0 2 2 2 2 RNA recognition motif RRM_3 PF08777.11 KKK21950.1 - 0.0071 16.4 0.0 1.9 8.6 0.0 2.5 2 0 0 2 2 2 2 RNA binding motif PPR_2 PF13041.6 KKK21951.1 - 1.3e-05 25.3 1.1 0.28 11.4 0.0 4.7 6 0 0 6 6 6 2 PPR repeat family TPR_14 PF13428.6 KKK21951.1 - 0.00021 21.8 0.1 36 5.6 0.0 5.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 KKK21951.1 - 0.0021 18.5 1.1 1.2 9.7 0.3 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat PPR PF01535.20 KKK21951.1 - 0.0093 16.2 7.3 1.3 9.4 0.1 5.9 7 0 0 7 7 7 1 PPR repeat Ribosomal_S18 PF01084.20 KKK21952.1 - 2e-15 56.7 0.1 3.8e-15 55.8 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S18 WD40 PF00400.32 KKK21953.1 - 2.8e-29 100.8 33.6 0.00024 21.8 0.1 11.3 11 1 1 12 12 12 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKK21953.1 - 5.5e-18 65.0 10.8 5.9e-06 26.5 0.1 7.9 4 3 6 10 10 10 6 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KKK21953.1 - 0.0016 17.2 0.1 0.006 15.3 0.0 1.9 2 1 0 2 2 2 1 Nucleoporin Nup120/160 PD40 PF07676.12 KKK21953.1 - 0.0023 17.8 0.4 0.41 10.6 0.0 4.3 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KKK21953.1 - 0.0034 16.4 1.9 22 3.8 0.1 4.7 4 1 0 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein IRF PF00605.17 KKK21953.1 - 0.02 15.2 1.0 5.3 7.4 0.2 2.5 2 0 0 2 2 2 0 Interferon regulatory factor transcription factor Me-amine-dh_H PF06433.11 KKK21953.1 - 0.096 11.5 0.0 0.36 9.6 0.0 1.9 1 1 1 2 2 2 0 Methylamine dehydrogenase heavy chain (MADH) FUSC_2 PF13515.6 KKK21954.1 - 1.3e-14 54.4 0.6 1.3e-14 54.4 0.6 2.3 2 1 1 3 3 3 1 Fusaric acid resistance protein-like ALMT PF11744.8 KKK21954.1 - 2.7e-05 23.2 3.0 0.01 14.7 0.0 2.7 3 0 0 3 3 3 2 Aluminium activated malate transporter FUSC PF04632.12 KKK21954.1 - 0.00033 19.3 6.6 0.012 14.2 0.1 2.9 2 1 0 3 3 3 2 Fusaric acid resistance protein family FUSC-like PF12805.7 KKK21954.1 - 0.0044 16.2 2.2 0.017 14.2 0.2 2.4 2 0 0 2 2 2 1 FUSC-like inner membrane protein yccS ArAE_2_N PF10337.9 KKK21954.1 - 0.036 13.1 0.1 0.13 11.3 0.1 1.9 2 0 0 2 2 2 0 Putative ER transporter, 6TM, N-terminal Ribosomal_S6e PF01092.19 KKK21955.1 - 1.1e-54 183.7 1.5 1.8e-54 183.0 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein S6e Lipase_GDSL PF00657.22 KKK21956.1 - 0.00023 21.2 0.0 0.00026 21.0 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase ANAPC4 PF12896.7 KKK21956.1 - 0.06 12.8 0.1 0.18 11.2 0.0 1.8 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 4 HMG_box PF00505.19 KKK21957.1 - 1.4e-22 79.8 1.5 2.9e-22 78.9 1.5 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KKK21957.1 - 3.6e-08 33.9 1.7 4.9e-08 33.4 0.7 1.8 2 0 0 2 2 2 1 HMG-box domain Fungal_trans PF04082.18 KKK21961.1 - 3e-08 33.0 0.0 3.1e-07 29.7 0.0 2.5 3 0 0 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK21961.1 - 5.9e-07 29.5 8.4 1.2e-06 28.5 8.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain LCIB_C_CA PF18599.1 KKK21961.1 - 0.25 10.6 0.4 0.39 10.0 0.4 1.2 1 0 0 1 1 1 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases DUF1688 PF07958.11 KKK21962.1 - 2e-161 537.4 0.0 2.3e-161 537.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) SPX PF03105.19 KKK21963.1 - 6.3e-40 138.3 0.7 4.8e-27 95.9 0.0 2.2 1 1 1 2 2 2 2 SPX domain Na_sulph_symp PF00939.19 KKK21963.1 - 9.2e-21 74.4 37.3 1.2e-18 67.4 22.8 2.2 1 1 1 2 2 2 2 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 KKK21963.1 - 2.2e-18 66.5 38.8 4.6e-18 65.5 32.1 2.7 2 1 1 3 3 3 2 Citrate transporter Cytochrome-c551 PF10643.9 KKK21963.1 - 3 7.4 5.0 3.3 7.2 0.2 2.5 2 0 0 2 2 2 0 Photosystem P840 reaction-centre cytochrome c-551 DUF4220 PF13968.6 KKK21963.1 - 4.3 6.6 6.8 0.48 9.8 1.8 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4220) Ribosomal_S8e PF01201.22 KKK21964.1 - 1.7e-53 180.5 2.1 2.9e-53 179.7 2.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S8e DUF2470 PF10615.9 KKK21964.1 - 2.9e-20 72.7 0.0 6.6e-20 71.5 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) DUF1516 PF07457.11 KKK21965.1 - 0.021 15.0 1.7 0.021 15.0 1.7 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1516) DUF2818 PF10993.8 KKK21965.1 - 0.53 10.9 3.8 0.76 10.4 0.5 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2818) AA_permease_2 PF13520.6 KKK21966.1 - 8.6e-46 156.6 41.4 1.1e-45 156.3 41.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KKK21966.1 - 4.4e-26 91.5 36.8 5.8e-26 91.1 36.8 1.1 1 0 0 1 1 1 1 Amino acid permease MRP-L27 PF09809.9 KKK21967.1 - 3.8e-15 55.7 0.2 4.5e-15 55.5 0.2 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 DUF2491 PF10679.9 KKK21967.1 - 0.056 12.6 0.1 0.065 12.4 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2491) DUF4554 PF15091.6 KKK21967.1 - 0.19 10.6 0.0 0.22 10.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) PARP PF00644.20 KKK21968.1 - 1.9e-11 44.0 0.5 4.8e-11 42.6 0.2 1.7 1 1 1 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain UQ_con PF00179.26 KKK21968.1 - 7.4e-06 25.7 0.0 2e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KKK21968.1 - 0.044 14.1 0.0 0.76 10.1 0.0 2.4 2 0 0 2 2 2 0 RWD domain Glyco_hydro81C PF17652.1 KKK21969.1 - 1.1e-168 560.9 5.9 1.5e-168 560.5 5.9 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 KKK21969.1 - 5.3e-116 387.3 2.4 7.9e-116 386.7 2.4 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 N-terminal domain Na_Ca_ex PF01699.24 KKK21969.1 - 1.9e-40 138.3 42.2 5.2e-21 75.2 17.3 2.4 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DUF1129 PF06570.11 KKK21969.1 - 1.3 8.5 4.5 1.9 8.0 3.6 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1129) Utp14 PF04615.13 KKK21970.1 - 1.1e-216 722.0 67.5 1.1e-216 722.0 67.5 2.1 1 1 1 2 2 2 1 Utp14 protein Ribosomal_S7 PF00177.21 KKK21971.1 - 1.5e-31 109.0 0.0 3.7e-31 107.8 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein S7p/S5e Lin-8 PF03353.15 KKK21971.1 - 0.091 12.3 3.5 0.13 11.8 3.5 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist CRAL_TRIO PF00650.20 KKK21972.1 - 2.5e-48 163.8 0.1 4.8e-48 162.9 0.1 1.5 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 KKK21972.1 - 5.4e-08 33.1 0.0 1.1e-07 32.1 0.0 1.5 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KKK21972.1 - 1.3e-07 31.6 0.1 4e-07 30.1 0.1 1.9 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain HD_3 PF13023.6 KKK21972.1 - 0.07 13.1 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 HD domain Glyco_hydro_36 PF17167.4 KKK21972.1 - 0.11 11.1 0.8 0.74 8.4 0.2 2.2 1 1 0 2 2 2 0 Glycosyl hydrolase 36 superfamily, catalytic domain Mei5 PF10376.9 KKK21972.1 - 7.2 6.4 8.4 0.83 9.5 4.0 1.6 2 0 0 2 2 2 0 Double-strand recombination repair protein ATP-synt_C PF00137.21 KKK21974.1 - 3.5e-28 97.7 35.6 8e-17 61.3 13.2 2.1 2 0 0 2 2 2 2 ATP synthase subunit C Pkinase PF00069.25 KKK21975.1 - 1.7e-06 27.6 0.1 2.2e-06 27.2 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain NIF PF03031.18 KKK21994.1 - 1.1e-53 181.2 0.0 2.1e-53 180.2 0.0 1.5 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase LRR_4 PF12799.7 KKK21994.1 - 4.7e-32 109.5 33.2 1.8e-08 34.5 0.7 7.0 1 1 8 10 10 10 10 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KKK21994.1 - 1.2e-17 63.4 34.1 2.9e-05 23.7 5.6 5.9 4 1 1 5 5 5 5 Leucine rich repeat LRR_9 PF14580.6 KKK21994.1 - 1.5e-12 47.3 13.4 1.2e-05 24.9 2.1 3.9 1 1 2 4 4 4 3 Leucine-rich repeat LRR_6 PF13516.6 KKK21994.1 - 3.6e-05 23.5 17.0 0.45 10.7 0.1 6.7 7 0 0 7 7 7 3 Leucine Rich repeat LRR_1 PF00560.33 KKK21994.1 - 0.098 13.3 23.4 18 6.4 0.3 8.9 8 2 0 8 8 8 0 Leucine Rich Repeat Gly_transf_sug PF04488.15 KKK21996.1 - 1e-11 45.3 0.0 2.5e-11 44.0 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif bZIP_2 PF07716.15 KKK21997.1 - 3e-13 49.6 13.6 5.9e-13 48.7 13.6 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 KKK21997.1 - 0.002 18.2 12.3 0.0036 17.3 12.3 1.4 1 0 0 1 1 1 1 bZIP transcription factor FPP PF05911.11 KKK21997.1 - 0.058 11.6 4.7 0.079 11.1 4.7 1.1 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil DUF4094 PF13334.6 KKK21997.1 - 0.074 13.5 0.6 0.15 12.5 0.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) TSC22 PF01166.18 KKK21997.1 - 0.14 12.5 0.8 0.33 11.3 0.8 1.7 1 0 0 1 1 1 0 TSC-22/dip/bun family DUF3552 PF12072.8 KKK21997.1 - 0.26 10.7 9.9 0.37 10.2 9.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Fungal_trans PF04082.18 KKK21998.1 - 6.4e-21 74.6 2.3 7.2e-21 74.4 0.1 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK21998.1 - 0.0001 22.4 9.5 0.00017 21.6 9.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sec63 PF02889.16 KKK21999.1 - 2e-163 541.7 0.0 1.6e-91 306.0 0.0 2.2 2 0 0 2 2 2 2 Sec63 Brl domain Peptidase_S9 PF00326.21 KKK21999.1 - 3.1e-49 167.3 0.0 9.5e-49 165.7 0.0 1.8 2 0 0 2 2 2 1 Prolyl oligopeptidase family DEAD PF00270.29 KKK21999.1 - 2.4e-48 164.2 0.1 2.6e-27 95.7 0.0 3.2 3 0 0 3 3 3 2 DEAD/DEAH box helicase Helicase_PWI PF18149.1 KKK21999.1 - 4.8e-30 104.0 0.1 1.3e-29 102.6 0.1 1.8 1 0 0 1 1 1 1 N-terminal helicase PWI domain ResIII PF04851.15 KKK21999.1 - 3.2e-25 89.1 0.0 2.8e-13 50.2 0.0 2.5 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KKK21999.1 - 4.7e-10 39.8 0.0 3.6e-07 30.5 0.0 3.6 2 1 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 KKK21999.1 - 1.2e-05 25.6 1.9 0.24 11.7 0.2 4.1 3 1 0 3 3 3 2 AAA domain Abhydrolase_1 PF00561.20 KKK21999.1 - 0.0022 17.7 0.1 0.0043 16.7 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold AXE1 PF05448.12 KKK21999.1 - 0.0032 16.2 0.0 0.089 11.5 0.0 2.5 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) AAA_19 PF13245.6 KKK21999.1 - 0.0046 17.3 0.0 3.2 8.1 0.0 2.8 2 0 0 2 2 2 1 AAA domain PhoH PF02562.16 KKK21999.1 - 0.0058 16.1 0.0 0.3 10.5 0.0 2.5 2 0 0 2 2 2 1 PhoH-like protein T2SSE PF00437.20 KKK21999.1 - 0.0065 15.6 0.0 1.3 8.1 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein Phage_TAC_5 PF08890.11 KKK21999.1 - 0.071 13.1 1.4 0.18 11.8 1.4 1.7 1 0 0 1 1 1 0 Phage XkdN-like tail assembly chaperone protein, TAC AAA_7 PF12775.7 KKK21999.1 - 0.17 11.4 0.0 8 5.9 0.0 2.6 2 0 0 2 2 2 0 P-loop containing dynein motor region MutS_V PF00488.21 KKK22000.1 - 2.2e-72 243.1 0.0 4.9e-72 241.9 0.0 1.6 2 0 0 2 2 2 1 MutS domain V MutS_III PF05192.18 KKK22000.1 - 3e-46 158.1 0.9 1.2e-45 156.1 0.9 2.0 1 1 0 1 1 1 1 MutS domain III MutS_I PF01624.20 KKK22000.1 - 5.7e-21 74.9 0.1 1.9e-20 73.2 0.0 2.0 2 0 0 2 2 2 1 MutS domain I MutS_II PF05188.17 KKK22000.1 - 0.00024 21.4 0.0 0.00058 20.1 0.0 1.7 1 0 0 1 1 1 1 MutS domain II AAA_23 PF13476.6 KKK22000.1 - 0.0087 16.6 0.4 0.53 10.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KKK22000.1 - 0.018 15.4 0.4 1.3 9.4 0.2 2.8 2 1 0 2 2 2 0 AAA ATPase domain AAA_27 PF13514.6 KKK22000.1 - 0.022 14.4 0.0 0.069 12.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KKK22000.1 - 0.057 13.2 0.0 0.16 11.7 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain HTH_AsnC-type PF13404.6 KKK22001.1 - 0.044 13.6 0.1 0.091 12.6 0.1 1.5 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain MFS_1 PF07690.16 KKK22002.1 - 1.8e-39 135.7 45.2 2.3e-39 135.3 43.8 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KKK22002.1 - 8.8e-19 67.3 11.2 2.2e-18 66.0 11.2 1.6 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KKK22002.1 - 9.5e-13 47.8 14.0 3.7e-11 42.5 6.7 2.7 2 1 0 2 2 2 2 Sugar (and other) transporter ADH_N PF08240.12 KKK22003.1 - 3.1e-25 88.2 4.0 4.9e-25 87.5 4.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KKK22003.1 - 6.7e-15 55.2 0.0 1.2e-14 54.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KKK22003.1 - 0.0015 18.1 0.2 0.0028 17.2 0.1 1.5 2 0 0 2 2 2 1 Glucose dehydrogenase C-terminus NAD_binding_10 PF13460.6 KKK22003.1 - 0.002 18.0 0.0 0.0032 17.4 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding 2-Hacid_dh_C PF02826.19 KKK22003.1 - 0.016 14.5 0.0 0.026 13.9 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ELFV_dehydrog PF00208.21 KKK22003.1 - 0.019 14.7 0.1 0.031 14.0 0.1 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ADH_zinc_N_2 PF13602.6 KKK22003.1 - 0.02 16.0 0.0 0.054 14.6 0.0 1.8 1 1 0 1 1 1 0 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KKK22003.1 - 0.1 11.9 0.1 0.25 10.6 0.1 1.5 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Ureidogly_lyase PF04115.12 KKK22004.1 - 5.5e-62 208.9 0.1 9.3e-31 107.0 0.0 2.1 2 0 0 2 2 2 2 Ureidoglycolate lyase Myc_N PF01056.18 KKK22004.1 - 0.0051 16.7 0.1 0.006 16.5 0.1 1.1 1 0 0 1 1 1 1 Myc amino-terminal region RNA_pol_3_Rpc31 PF11705.8 KKK22004.1 - 0.022 15.0 0.2 0.054 13.8 0.2 1.6 1 1 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 AMP-binding PF00501.28 KKK22005.1 - 2.3e-37 128.6 0.0 1.6e-36 125.9 0.0 2.1 1 1 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 KKK22005.1 - 2.4e-06 27.4 2.0 6e-06 26.1 2.0 1.8 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus FeoA PF04023.14 KKK22005.1 - 0.089 13.1 0.0 0.23 11.8 0.0 1.6 1 0 0 1 1 1 0 FeoA domain Drc1-Sld2 PF11719.8 KKK22007.1 - 0.92 9.0 7.6 1.2 8.6 7.6 1.0 1 0 0 1 1 1 0 DNA replication and checkpoint protein PAN_3 PF08277.12 KKK22007.1 - 3.6 7.5 7.8 6.1 6.7 7.7 1.5 1 1 0 1 1 1 0 PAN-like domain Ank_4 PF13637.6 KKK22032.1 - 6.7e-14 52.1 0.7 1.1e-05 25.9 0.0 3.2 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KKK22032.1 - 5.8e-11 42.8 0.0 8.7e-06 26.2 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KKK22032.1 - 6.2e-10 39.1 0.3 8.8e-06 25.9 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KKK22032.1 - 1.1e-09 37.7 0.7 0.00035 20.8 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 KKK22032.1 - 1.2e-08 35.0 0.7 8.7e-06 26.0 0.1 3.5 3 0 0 3 3 3 1 Ankyrin repeat KilA-N PF04383.13 KKK22032.1 - 0.00015 21.6 0.0 0.00058 19.7 0.0 1.9 1 0 0 1 1 1 1 KilA-N domain HALZ PF02183.18 KKK22032.1 - 1.2 9.5 4.9 3.1 8.1 0.1 2.4 2 0 0 2 2 2 0 Homeobox associated leucine zipper NDUF_B7 PF05676.13 KKK22033.1 - 4e-30 103.3 6.6 4.8e-30 103.1 6.6 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.10 KKK22033.1 - 0.018 15.1 2.4 0.024 14.6 2.4 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like GCS PF03074.16 KKK22034.1 - 1.1e-174 581.1 0.0 1.3e-174 580.8 0.0 1.1 1 0 0 1 1 1 1 Glutamate-cysteine ligase Cytochrom_B561 PF03188.16 KKK22034.1 - 0.23 11.6 0.0 6.3 6.9 0.0 2.2 2 0 0 2 2 2 0 Eukaryotic cytochrome b561 AA_permease_2 PF13520.6 KKK22036.1 - 3.4e-43 148.1 33.7 5.8e-43 147.3 33.7 1.3 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KKK22036.1 - 1.3e-18 66.9 29.0 2e-18 66.3 29.0 1.3 1 0 0 1 1 1 1 Amino acid permease DUF829 PF05705.14 KKK22043.1 - 3.8e-54 184.1 0.0 5.6e-54 183.6 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Rad51 PF08423.11 KKK22043.1 - 5.4e-42 143.8 0.0 2.7e-39 135.0 0.0 2.2 2 0 0 2 2 2 2 Rad51 ATPase PF06745.13 KKK22043.1 - 1.7e-08 34.1 0.0 3.7e-08 33.0 0.0 1.5 1 1 0 1 1 1 1 KaiC AAA_25 PF13481.6 KKK22043.1 - 7.5e-08 32.2 0.0 1.5e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain RecA PF00154.21 KKK22043.1 - 0.012 15.0 0.0 0.021 14.3 0.0 1.3 1 0 0 1 1 1 0 recA bacterial DNA recombination protein RETICULATA-like PF11891.8 KKK22043.1 - 0.046 13.6 0.0 0.078 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein RETICULATA-related Pox_A32 PF04665.12 KKK22043.1 - 0.066 12.7 0.2 0.11 11.9 0.2 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein IGPD PF00475.18 KKK22045.1 - 8.4e-56 188.3 0.4 1.1e-55 187.9 0.4 1.1 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase Arena_RNA_pol PF06317.11 KKK22045.1 - 0.033 11.4 0.0 0.042 11.0 0.0 1.0 1 0 0 1 1 1 0 Arenavirus RNA polymerase Hat1_N PF10394.9 KKK22046.1 - 3.2e-56 190.0 0.0 5.3e-56 189.3 0.0 1.4 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus Acetyltransf_1 PF00583.25 KKK22046.1 - 0.07 13.4 0.0 0.19 12.0 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Zip PF02535.22 KKK22047.1 - 4e-36 124.9 12.5 6.9e-28 97.8 5.0 3.1 2 1 0 2 2 2 2 ZIP Zinc transporter 3HCDH_N PF02737.18 KKK22048.1 - 1.5e-23 83.7 0.6 9e-22 77.8 0.0 2.2 1 1 1 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 KKK22048.1 - 2.3e-10 40.9 0.0 7.5e-10 39.3 0.0 1.8 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain LSM PF01423.22 KKK22049.1 - 5.4e-18 64.4 0.0 7.5e-18 64.0 0.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KKK22049.1 - 0.0014 18.7 0.0 0.0022 18.1 0.0 1.4 1 1 1 2 2 2 1 Ataxin 2 SM domain API5 PF05918.11 KKK22049.1 - 5.5 5.7 6.1 7 5.3 6.1 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) DSPc PF00782.20 KKK22050.1 - 1.1e-09 38.2 0.0 2e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KKK22050.1 - 0.005 16.4 0.0 0.0083 15.7 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Cellulose_synt PF03552.14 KKK22050.1 - 0.24 9.9 0.0 0.32 9.4 0.0 1.1 1 0 0 1 1 1 0 Cellulose synthase PLA2_B PF01735.18 KKK22051.1 - 8.7e-27 93.7 0.0 1.6e-26 92.8 0.0 1.4 1 1 0 1 1 1 1 Lysophospholipase catalytic domain Exo70 PF03081.15 KKK22052.1 - 5.3e-89 298.9 0.0 7.3e-89 298.4 0.0 1.2 1 0 0 1 1 1 1 Exo70 exocyst complex subunit Bap31_Bap29_C PF18035.1 KKK22052.1 - 0.12 12.4 0.0 0.37 10.8 0.0 1.8 1 0 0 1 1 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain DASH_Dam1 PF08653.10 KKK22052.1 - 0.13 12.1 0.3 57 3.6 0.0 3.6 3 0 0 3 3 3 0 DASH complex subunit Dam1 Prominin PF05478.11 KKK22052.1 - 0.15 10.0 0.6 0.24 9.3 0.6 1.2 1 0 0 1 1 1 0 Prominin Hyr1 PF15789.5 KKK22052.1 - 0.19 11.3 1.5 5.1 6.7 0.4 2.5 2 0 0 2 2 2 0 Hyphally regulated cell wall GPI-anchored protein 1 Lyase_1 PF00206.20 KKK22053.1 - 2.6e-21 76.3 0.0 4.9e-21 75.4 0.0 1.4 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.9 KKK22053.1 - 1.4e-18 67.1 0.0 5.1e-18 65.4 0.0 2.0 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus PPR_2 PF13041.6 KKK22054.1 - 3.7e-13 49.4 0.1 0.00053 20.1 0.1 6.6 4 3 3 7 7 7 2 PPR repeat family PPR_long PF17177.4 KKK22054.1 - 1.4e-11 44.2 0.8 7.3e-08 32.0 0.1 2.6 1 1 1 2 2 2 2 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 KKK22054.1 - 7.4e-09 35.3 2.9 0.065 13.5 0.1 5.3 5 0 0 5 5 5 3 PPR repeat PPR_3 PF13812.6 KKK22054.1 - 8.1e-09 35.4 0.0 0.0002 21.4 0.0 4.4 3 1 1 4 4 4 2 Pentatricopeptide repeat domain Mic1 PF07035.12 KKK22054.1 - 0.00017 21.3 0.0 0.067 12.9 0.1 2.4 2 0 0 2 2 2 2 Colon cancer-associated protein Mic1-like PPR_1 PF12854.7 KKK22054.1 - 0.032 13.9 0.0 0.73 9.6 0.0 2.9 3 0 0 3 3 3 0 PPR repeat AIM24 PF01987.17 KKK22055.1 - 2.4e-47 161.3 0.0 3.1e-47 161.0 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 ABC_membrane PF00664.23 KKK22056.1 - 1.9e-39 136.0 11.1 2.4e-39 135.6 11.1 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 KKK22056.1 - 9.5e-35 120.1 0.0 1.9e-34 119.1 0.0 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KKK22056.1 - 9.7e-05 21.9 0.1 0.093 12.1 0.0 2.4 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 KKK22056.1 - 0.0011 17.8 0.0 0.011 14.5 0.0 2.0 2 0 0 2 2 2 1 Predicted ATPase of the ABC class AAA_22 PF13401.6 KKK22056.1 - 0.0011 19.2 0.1 0.0063 16.8 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KKK22056.1 - 0.0014 19.0 0.0 0.0033 17.8 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 KKK22056.1 - 0.0023 17.8 0.0 0.018 14.8 0.0 2.2 1 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system GPAT_N PF14829.6 KKK22056.1 - 0.0029 17.6 0.0 5.7 7.0 0.0 3.2 3 0 0 3 3 3 1 Glycerol-3-phosphate acyltransferase N-terminal ATP-synt_ab PF00006.25 KKK22056.1 - 0.0042 16.8 0.0 0.0086 15.7 0.0 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_14 PF13173.6 KKK22056.1 - 0.0055 16.7 0.0 0.1 12.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 KKK22056.1 - 0.0093 16.4 0.0 0.12 12.8 0.0 2.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 KKK22056.1 - 0.011 16.2 0.0 0.03 14.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KKK22056.1 - 0.012 15.3 0.1 0.028 14.2 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Rad17 PF03215.15 KKK22056.1 - 0.013 15.4 0.0 0.041 13.8 0.0 1.8 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_33 PF13671.6 KKK22056.1 - 0.017 15.3 0.0 1 9.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 KKK22056.1 - 0.018 14.9 0.0 0.11 12.4 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase AAA_28 PF13521.6 KKK22056.1 - 0.024 14.9 0.0 0.09 13.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 KKK22056.1 - 0.055 13.2 0.4 10 5.8 0.0 3.0 3 0 0 3 3 3 0 IstB-like ATP binding protein MMR_HSR1 PF01926.23 KKK22056.1 - 0.057 13.5 0.0 0.19 11.9 0.0 1.9 1 0 0 1 1 1 0 50S ribosome-binding GTPase Zeta_toxin PF06414.12 KKK22056.1 - 0.058 12.7 0.3 0.47 9.7 0.0 2.6 3 0 0 3 3 3 0 Zeta toxin AAA_24 PF13479.6 KKK22056.1 - 0.091 12.5 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.7 KKK22056.1 - 0.1 11.5 0.0 0.28 10.1 0.0 1.7 1 1 0 1 1 1 0 AAA-like domain AAA_18 PF13238.6 KKK22056.1 - 0.16 12.5 0.0 0.64 10.6 0.0 2.1 2 0 0 2 2 1 0 AAA domain SbcCD_C PF13558.6 KKK22056.1 - 0.26 11.5 2.4 1.5 9.1 0.4 2.9 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit MFS_1 PF07690.16 KKK22057.1 - 8.7e-20 70.9 26.0 1.1e-19 70.6 25.6 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KKK22057.1 - 7.3e-05 21.8 2.1 7.3e-05 21.8 2.1 1.9 1 1 1 2 2 2 1 Sugar (and other) transporter DUF2304 PF10066.9 KKK22057.1 - 0.17 12.1 2.2 0.15 12.3 0.3 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2304) MFS_1_like PF12832.7 KKK22057.1 - 0.77 8.5 13.2 0.059 12.2 4.6 2.3 1 1 2 3 3 3 0 MFS_1 like family BUD22 PF09073.10 KKK22101.1 - 4.7e-110 368.9 25.8 5.4e-110 368.7 25.8 1.0 1 0 0 1 1 1 1 BUD22 Fungal_trans PF04082.18 KKK22102.1 - 2.5e-26 92.3 0.0 4.3e-26 91.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK22102.1 - 4.1e-06 26.8 9.4 8.4e-06 25.8 9.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cyt-b5 PF00173.28 KKK22113.1 - 1.2e-21 76.6 0.1 1.3e-21 76.5 0.1 1.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain K_oxygenase PF13434.6 KKK22114.1 - 2.6e-110 368.8 0.0 3.1e-110 368.5 0.0 1.1 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 KKK22114.1 - 2.5e-07 30.3 0.0 0.00034 20.0 0.0 2.3 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DUF3530 PF12048.8 KKK22114.1 - 0.079 12.4 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) Pkinase PF00069.25 KKK22115.1 - 3.4e-40 138.1 0.0 6.1e-39 134.0 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK22115.1 - 4.4e-24 85.2 0.0 6.7e-24 84.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase OB_NTP_bind PF07717.16 KKK22116.1 - 7.8e-22 77.4 0.0 2.6e-21 75.8 0.0 1.9 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 KKK22116.1 - 1.2e-19 70.5 0.0 1.2e-19 70.5 0.0 4.2 4 2 0 4 4 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KKK22116.1 - 2.3e-13 50.5 0.0 5.5e-13 49.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KKK22116.1 - 3.3e-08 33.5 0.1 7.7e-08 32.3 0.1 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KKK22116.1 - 1.9e-05 25.0 0.0 6.6e-05 23.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KKK22116.1 - 0.00016 21.4 1.0 0.0003 20.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 KKK22116.1 - 0.00035 19.7 0.0 0.00075 18.6 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.6 KKK22116.1 - 0.00052 20.4 1.5 0.00063 20.1 0.1 1.9 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.22 KKK22116.1 - 0.0045 16.6 0.2 0.011 15.3 0.2 1.7 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain PWI PF01480.17 KKK22116.1 - 0.0087 16.4 0.0 0.026 14.9 0.0 1.8 1 0 0 1 1 1 1 PWI domain AAA_23 PF13476.6 KKK22116.1 - 0.12 12.9 0.0 0.12 12.9 0.0 4.0 1 1 2 3 3 1 0 AAA domain DLIC PF05783.11 KKK22116.1 - 0.15 10.8 4.1 0.28 10.0 2.6 2.0 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) SSP160 PF06933.11 KKK22116.1 - 0.21 9.8 8.3 0.33 9.1 8.3 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Mannitol_dh PF01232.23 KKK22116.1 - 0.25 11.5 1.2 0.88 9.7 0.1 2.4 2 0 0 2 2 2 0 Mannitol dehydrogenase Rossmann domain ABC_tran PF00005.27 KKK22116.1 - 0.26 11.8 2.2 1 9.9 0.1 2.7 1 1 1 2 2 2 0 ABC transporter Hydrolase_4 PF12146.8 KKK22122.1 - 0.00084 18.7 0.0 0.0014 18.0 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 KKK22122.1 - 0.00085 19.1 0.0 0.0017 18.2 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_3 PF07859.13 KKK22122.1 - 0.0074 16.2 0.0 0.013 15.3 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KKK22122.1 - 0.012 16.2 5.2 0.026 15.1 5.2 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family DUF676 PF05057.14 KKK22122.1 - 0.015 14.9 0.0 0.036 13.6 0.0 1.7 1 1 0 1 1 1 0 Putative serine esterase (DUF676) LCAT PF02450.15 KKK22122.1 - 0.042 13.0 0.0 0.062 12.5 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Abhydrolase_2 PF02230.16 KKK22122.1 - 0.22 11.3 0.3 0.44 10.3 0.0 1.6 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Chs7 PF12271.8 KKK22123.1 - 2.1e-109 365.3 14.7 2e-91 306.3 8.6 2.0 1 1 1 2 2 2 2 Chitin synthase export chaperone DUF3382 PF11862.8 KKK22123.1 - 0.014 15.7 1.6 0.014 15.7 1.6 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF3382) DUF2871 PF11070.8 KKK22123.1 - 0.24 11.7 6.8 0.24 11.7 0.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2871) Ribosomal_S6 PF01250.17 KKK22124.1 - 8e-23 80.5 0.0 1e-22 80.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S6 4HBT_3 PF13622.6 KKK22125.1 - 1e-31 111.1 0.2 2.2e-31 110.0 0.2 1.5 1 1 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 KKK22125.1 - 0.00013 21.9 0.2 0.68 9.8 0.0 3.8 2 2 1 3 3 3 2 Acyl-CoA thioesterase PD40 PF07676.12 KKK22125.1 - 0.074 13.0 0.1 0.29 11.1 0.1 2.0 1 0 0 1 1 1 0 WD40-like Beta Propeller Repeat ANAPC4_WD40 PF12894.7 KKK22125.1 - 0.086 13.1 0.0 0.21 11.9 0.0 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain GCV_H PF01597.19 KKK22126.1 - 6.4e-37 126.2 0.5 7.6e-37 125.9 0.5 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein Biotin_lipoyl PF00364.22 KKK22126.1 - 0.11 12.3 0.3 0.3 10.9 0.1 1.7 1 1 0 1 1 1 0 Biotin-requiring enzyme bZIP_1 PF00170.21 KKK22127.1 - 9.4e-08 32.0 6.6 1.5e-07 31.4 6.6 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KKK22127.1 - 0.0068 16.5 8.6 0.013 15.5 8.6 1.4 1 0 0 1 1 1 1 Basic region leucine zipper IMUP PF15761.5 KKK22127.1 - 0.39 11.4 2.7 0.72 10.6 2.7 1.4 1 0 0 1 1 1 0 Immortalisation up-regulated protein bZIP_Maf PF03131.17 KKK22127.1 - 2.1 8.9 11.9 0.055 14.0 4.9 1.8 2 0 0 2 2 2 0 bZIP Maf transcription factor Abhydrolase_6 PF12697.7 KKK22128.1 - 1e-05 26.2 0.0 1.6e-05 25.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.18 KKK22128.1 - 0.12 11.9 0.1 0.33 10.5 0.1 1.7 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) DUF1412 PF07203.11 KKK22129.1 - 0.15 12.3 0.2 0.32 11.2 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1412) DUF3336 PF11815.8 KKK22130.1 - 5.1e-36 123.4 0.8 8.4e-36 122.7 0.8 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 KKK22130.1 - 1.9e-19 70.6 0.0 3.5e-19 69.8 0.0 1.4 1 0 0 1 1 1 1 Patatin-like phospholipase PNP_UDP_1 PF01048.20 KKK22131.1 - 4.4e-40 137.4 0.1 5.2e-40 137.1 0.1 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily 6PGD PF00393.19 KKK22132.1 - 1.2e-83 280.9 0.0 1.4e-83 280.6 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 KKK22132.1 - 3.9e-28 98.6 0.1 8.5e-28 97.5 0.1 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 KKK22132.1 - 2.8e-05 24.1 0.2 4.6e-05 23.4 0.2 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 KKK22132.1 - 0.0012 18.5 0.2 0.0021 17.6 0.2 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.19 KKK22132.1 - 0.0012 18.2 0.1 0.0021 17.4 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox PF00070.27 KKK22132.1 - 0.0051 17.3 0.2 0.011 16.3 0.2 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase F420_oxidored PF03807.17 KKK22132.1 - 0.0053 17.3 0.2 0.022 15.3 0.0 2.0 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.23 KKK22132.1 - 0.013 15.5 0.2 0.024 14.6 0.2 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.16 KKK22132.1 - 0.023 14.3 0.3 0.042 13.5 0.3 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox_2 PF07992.14 KKK22132.1 - 0.03 13.6 0.0 0.054 12.7 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF2235 PF09994.9 KKK22133.1 - 1.3e-94 316.8 0.0 1.8e-94 316.4 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) MPTase-PolyVal PF18818.1 KKK22134.1 - 0.0075 16.3 0.0 0.0082 16.2 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase superfamily domain Coiled-coil_56 PF09813.9 KKK22134.1 - 0.64 10.1 4.2 1.1 9.4 2.3 1.8 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 56 OCD_Mu_crystall PF02423.15 KKK22135.1 - 5.3e-11 42.0 0.0 1.1e-10 40.9 0.0 1.5 1 1 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.20 KKK22135.1 - 0.00054 20.0 0.0 0.024 14.7 0.0 2.6 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Proteasome_A_N PF10584.9 KKK22135.1 - 0.17 11.6 0.0 0.39 10.4 0.0 1.6 1 0 0 1 1 1 0 Proteasome subunit A N-terminal signature Pro_dh PF01619.18 KKK22136.1 - 2.1e-64 217.9 0.2 2.5e-64 217.7 0.2 1.1 1 0 0 1 1 1 1 Proline dehydrogenase AA_permease PF00324.21 KKK22137.1 - 1.5e-130 436.0 45.9 1.8e-130 435.7 45.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KKK22137.1 - 2.3e-30 105.8 50.8 2.8e-30 105.5 50.8 1.0 1 0 0 1 1 1 1 Amino acid permease Aldedh PF00171.22 KKK22138.1 - 1.9e-110 369.5 0.1 2.3e-110 369.3 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family MARVEL PF01284.23 KKK22139.1 - 7.8e-09 35.7 7.1 1.1e-08 35.3 7.1 1.2 1 0 0 1 1 1 1 Membrane-associating domain DUF4013 PF13197.6 KKK22139.1 - 0.0031 17.4 6.8 0.88 9.4 0.2 2.8 2 1 0 2 2 2 2 Protein of unknown function (DUF4013) TMEM223 PF14640.6 KKK22139.1 - 0.0062 16.7 0.1 0.0096 16.1 0.1 1.2 1 0 0 1 1 1 1 Transmembrane protein 223 SecG PF03840.14 KKK22139.1 - 0.024 14.7 0.7 0.27 11.3 0.1 2.7 3 0 0 3 3 3 0 Preprotein translocase SecG subunit CbtA PF09490.10 KKK22139.1 - 0.058 13.2 1.6 0.14 11.9 1.2 1.8 1 1 1 2 2 2 0 Probable cobalt transporter subunit (CbtA) Sulfatase PF00884.23 KKK22144.1 - 3.9e-75 253.1 0.0 4.8e-75 252.8 0.0 1.1 1 0 0 1 1 1 1 Sulfatase DUF498 PF04430.14 KKK22148.1 - 1.8e-29 102.0 0.0 2.4e-29 101.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) Alk_phosphatase PF00245.20 KKK22149.1 - 1.5e-97 327.2 0.0 2e-97 326.8 0.0 1.2 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.18 KKK22149.1 - 0.00052 19.4 0.0 0.001 18.5 0.0 1.5 1 0 0 1 1 1 1 Metalloenzyme superfamily ABC_membrane PF00664.23 KKK22150.1 - 1e-36 127.0 11.4 2.3e-36 125.9 11.4 1.6 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 KKK22150.1 - 1.5e-33 116.2 0.0 3.4e-33 115.0 0.0 1.7 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KKK22150.1 - 5.7e-07 29.2 0.6 2.8e-05 23.7 0.0 2.7 2 1 1 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KKK22150.1 - 0.0055 17.0 0.1 0.035 14.4 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KKK22150.1 - 0.015 15.7 3.0 0.34 11.3 3.0 2.6 1 1 0 1 1 1 0 AAA ATPase domain SbcCD_C PF13558.6 KKK22150.1 - 0.025 14.8 1.1 0.46 10.7 0.3 3.1 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 KKK22150.1 - 0.039 13.7 0.1 0.1 12.4 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KKK22150.1 - 0.067 13.1 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase Glyco_hydro_16 PF00722.21 KKK22151.1 - 1.1e-42 145.5 7.8 1.1e-42 145.5 7.8 2.0 2 1 0 2 2 2 1 Glycosyl hydrolases family 16 DUF1180 PF06679.12 KKK22151.1 - 0.83 10.0 4.9 1.3 9.4 4.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) HNF-1_N PF04814.13 KKK22151.1 - 2.6 8.6 6.9 4.9 7.7 6.9 1.4 1 0 0 1 1 1 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus OHCU_decarbox PF09349.10 KKK22165.1 - 9.3e-43 146.4 0.0 1.5e-42 145.7 0.0 1.3 1 0 0 1 1 1 1 OHCU decarboxylase WD40 PF00400.32 KKK22165.1 - 1.7e-25 88.8 7.7 0.0003 21.5 0.1 8.1 7 1 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKK22165.1 - 6.9e-06 26.3 0.0 2 8.8 0.0 4.8 4 1 2 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KKK22165.1 - 0.035 12.8 0.4 13 4.2 0.1 3.2 2 1 1 3 3 3 0 Nucleoporin Nup120/160 Fn3-like PF14310.6 KKK22169.1 - 2.6e-25 88.3 0.9 8.2e-23 80.3 0.1 2.2 2 0 0 2 2 2 2 Fibronectin type III-like domain Nup54 PF13874.6 KKK22170.1 - 4.8e-41 140.1 1.6 7.2e-41 139.6 0.0 2.0 2 0 0 2 2 2 1 Nucleoporin complex subunit 54 Nup54_57_C PF18570.1 KKK22170.1 - 1.8e-11 43.4 2.6 3.3e-11 42.5 2.6 1.5 1 0 0 1 1 1 1 NUP57/Nup54 C-terminal domain Nucleoporin_FG PF13634.6 KKK22170.1 - 8.3e-05 23.4 90.1 1.8e+04 -19.3 90.1 3.6 1 1 0 1 1 1 0 Nucleoporin FG repeat region Fib_alpha PF08702.10 KKK22170.1 - 0.00027 21.1 0.5 0.00062 20.0 0.5 1.5 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family DUF4200 PF13863.6 KKK22170.1 - 8.2 6.9 8.8 6.4e+02 0.7 8.8 2.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) Tom5 PF10642.9 KKK22171.1 - 1.2e-22 79.6 0.1 1.3e-22 79.5 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit or translocase Med26 PF08711.11 KKK22172.1 - 6.2e-12 45.3 0.0 1.3e-11 44.4 0.0 1.6 1 0 0 1 1 1 1 TFIIS helical bundle-like domain CHCH PF06747.13 KKK22173.1 - 6.7e-06 26.1 4.6 6.7e-06 26.1 4.6 2.5 3 0 0 3 3 3 2 CHCH domain CX9C PF16860.5 KKK22173.1 - 0.0032 17.5 9.5 0.0039 17.2 3.3 2.3 2 0 0 2 2 2 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, DNA_circ_N PF07157.12 KKK22173.1 - 0.18 12.2 0.0 0.26 11.7 0.0 1.3 1 0 0 1 1 1 0 DNA circularisation protein N-terminus Pet191_N PF10203.9 KKK22173.1 - 0.26 11.6 10.3 1.4 9.2 1.2 2.9 1 1 1 3 3 3 0 Cytochrome c oxidase assembly protein PET191 Cmc1 PF08583.10 KKK22173.1 - 0.63 10.1 14.9 1.4 9.0 4.0 2.3 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like COX6B PF02297.17 KKK22173.1 - 1.3 9.3 10.0 7.2 6.9 0.7 2.2 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb MCM PF00493.23 KKK22174.1 - 7.4e-99 329.4 0.1 1e-98 328.9 0.1 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KKK22174.1 - 1.1e-39 135.1 0.7 2.3e-39 134.1 0.7 1.5 1 0 0 1 1 1 1 MCM OB domain MCM6_C PF18263.1 KKK22174.1 - 1.1e-33 115.7 1.0 1.1e-33 115.7 1.0 2.2 2 0 0 2 2 2 1 MCM6 C-terminal winged-helix domain MCM_lid PF17855.1 KKK22174.1 - 2.3e-24 85.6 0.4 7.9e-24 83.9 0.4 2.0 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KKK22174.1 - 3.3e-21 75.8 0.7 9.8e-21 74.3 0.7 1.9 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 KKK22174.1 - 2.4e-05 23.8 0.0 0.00024 20.6 0.0 2.4 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI GIDA_assoc PF13932.6 KKK22174.1 - 0.0022 18.2 0.4 0.0049 17.1 0.4 1.5 1 0 0 1 1 1 1 GidA associated domain AAA_5 PF07728.14 KKK22174.1 - 0.0029 17.6 0.0 0.0074 16.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 KKK22174.1 - 0.0037 17.1 0.0 0.015 15.1 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KKK22174.1 - 0.004 16.9 0.0 0.0083 15.9 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain S8_pro-domain PF16470.5 KKK22175.1 - 0.0022 18.7 0.6 0.0044 17.7 0.6 1.5 1 0 0 1 1 1 1 Peptidase S8 pro-domain DLH PF01738.18 KKK22176.1 - 4.6e-09 36.2 0.0 5.5e-09 35.9 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family cobW PF02492.19 KKK22177.1 - 7.4e-33 113.6 0.0 9.1e-33 113.3 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 KKK22177.1 - 1.1e-05 24.6 1.2 0.00013 21.0 1.2 2.0 1 1 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB MMR_HSR1 PF01926.23 KKK22177.1 - 0.007 16.4 0.0 0.014 15.5 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_18 PF13238.6 KKK22177.1 - 0.016 15.7 0.0 0.025 15.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KKK22177.1 - 0.018 15.4 0.0 0.024 15.0 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.14 KKK22177.1 - 0.025 14.6 0.0 0.037 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) TIP49 PF06068.13 KKK22177.1 - 0.025 13.8 0.0 0.038 13.2 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain IstB_IS21 PF01695.17 KKK22177.1 - 0.044 13.5 0.0 0.085 12.6 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein PRK PF00485.18 KKK22177.1 - 0.055 13.2 0.1 0.19 11.5 0.0 1.8 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_21 PF13304.6 KKK22177.1 - 0.068 13.0 0.0 0.12 12.1 0.0 1.5 1 1 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KKK22177.1 - 0.11 13.0 0.0 0.13 12.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain CbiA PF01656.23 KKK22177.1 - 0.12 12.4 0.0 0.19 11.8 0.0 1.4 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Zeta_toxin PF06414.12 KKK22177.1 - 0.16 11.2 0.0 0.28 10.5 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin NACHT PF05729.12 KKK22177.1 - 0.16 11.9 0.0 0.26 11.2 0.0 1.3 1 0 0 1 1 1 0 NACHT domain ResIII PF04851.15 KKK22177.1 - 0.18 11.8 0.0 0.26 11.3 0.0 1.4 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit MFS_1 PF07690.16 KKK22182.1 - 3.5e-41 141.3 34.6 3.5e-41 141.3 34.6 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KKK22182.1 - 7.8e-11 41.5 7.0 7.8e-11 41.5 7.0 3.1 3 0 0 3 3 3 2 Sugar (and other) transporter MFS_4 PF06779.14 KKK22182.1 - 6.5e-06 25.7 5.4 6.5e-06 25.7 5.4 2.3 3 1 0 3 3 3 1 Uncharacterised MFS-type transporter YbfB OATP PF03137.20 KKK22182.1 - 0.073 11.4 3.8 0.024 12.9 0.6 1.9 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family DUF2235 PF09994.9 KKK22183.1 - 1.9e-60 204.7 0.4 5.7e-48 163.7 0.0 2.1 1 1 1 2 2 2 2 Uncharacterized alpha/beta hydrolase domain (DUF2235) Sulfatase PF00884.23 KKK22184.1 - 9.5e-66 222.3 1.1 1.2e-65 221.9 1.1 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 KKK22184.1 - 0.0084 15.7 1.7 2.2 7.8 0.3 2.6 3 0 0 3 3 3 2 Type I phosphodiesterase / nucleotide pyrophosphatase DUF4976 PF16347.5 KKK22184.1 - 0.03 14.6 0.1 0.067 13.5 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4976) MAPEG PF01124.18 KKK22185.1 - 6.8e-22 77.8 0.3 7.8e-22 77.6 0.3 1.0 1 0 0 1 1 1 1 MAPEG family SKG6 PF08693.10 KKK22186.1 - 0.062 12.7 0.1 0.14 11.6 0.1 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain SR-25 PF10500.9 KKK22186.1 - 1.4 8.4 7.3 3 7.4 7.3 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein RAP1 PF07218.11 KKK22186.1 - 4.6 5.4 5.9 6.2 5.0 5.9 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Metallophos PF00149.28 KKK22187.1 - 1e-32 114.3 1.1 1.9e-32 113.5 1.1 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.6 KKK22187.1 - 3.6e-14 53.4 0.4 1.2e-13 51.7 0.1 2.1 2 0 0 2 2 2 1 Iron/zinc purple acid phosphatase-like protein C Pur_ac_phosph_N PF16656.5 KKK22187.1 - 1.4e-12 48.0 0.7 3.9e-12 46.6 0.3 2.0 2 0 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain PhoD_N PF16655.5 KKK22187.1 - 0.1 13.2 0.1 0.27 11.8 0.1 1.7 1 0 0 1 1 1 0 PhoD-like phosphatase, N-terminal domain DUF3533 PF12051.8 KKK22188.1 - 1.5e-102 343.4 10.9 2e-102 342.9 10.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) Inhibitor_I36 PF03995.13 KKK22188.1 - 0.11 12.4 0.2 3.7 7.5 0.1 2.3 2 0 0 2 2 2 0 Peptidase inhibitor family I36 Aldo_ket_red PF00248.21 KKK22189.1 - 6.5e-56 189.7 0.0 7.4e-56 189.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Caps_synth PF05704.12 KKK22190.1 - 3.3e-08 33.2 0.0 9.2e-08 31.8 0.0 1.7 1 1 0 1 1 1 1 Capsular polysaccharide synthesis protein Gly_transf_sug PF04488.15 KKK22190.1 - 0.0017 18.9 0.0 0.0041 17.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif DUF4044 PF13253.6 KKK22190.1 - 0.12 11.9 0.3 0.3 10.6 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4044) A_deaminase PF00962.22 KKK22192.1 - 1.5e-20 73.8 0.0 2.1e-20 73.3 0.0 1.4 1 1 0 1 1 1 1 Adenosine/AMP deaminase NdhL PF10716.9 KKK22194.1 - 0.11 12.5 1.1 0.37 10.8 1.1 1.9 1 0 0 1 1 1 0 NADH dehydrogenase transmembrane subunit CorA PF01544.18 KKK22195.1 - 0.00015 21.2 0.6 0.00032 20.1 0.6 1.5 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein 7TM_GPCR_Sru PF10322.9 KKK22195.1 - 0.031 13.6 0.1 0.066 12.5 0.1 1.5 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Sru P53_TAD PF08563.11 KKK22195.1 - 0.11 12.0 0.2 0.2 11.2 0.2 1.5 1 0 0 1 1 1 0 P53 transactivation motif DUF5326 PF17260.2 KKK22195.1 - 2 8.6 4.5 5.6 7.2 4.5 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5326) DUF1635 PF07795.11 KKK22196.1 - 0.022 14.6 0.2 0.03 14.2 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) Phosphoesterase PF04185.14 KKK22197.1 - 2.8e-35 122.2 7.3 5.2e-34 118.0 7.1 2.3 1 1 0 1 1 1 1 Phosphoesterase family DNA_ligase_C PF17879.1 KKK22197.1 - 0.034 14.2 0.1 0.069 13.2 0.1 1.5 1 0 0 1 1 1 0 DNA ligase C-terminal domain HIF-1a_CTAD PF08778.10 KKK22197.1 - 0.077 12.6 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 HIF-1 alpha C terminal transactivation domain Cu-oxidase_3 PF07732.15 KKK22199.1 - 2.5e-47 159.8 3.1 2.8e-46 156.4 0.2 3.3 3 1 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 KKK22199.1 - 1.3e-39 135.0 6.3 2.5e-36 124.5 1.0 3.7 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 KKK22199.1 - 9.3e-38 129.8 0.6 3.6e-37 127.9 0.3 2.2 2 0 0 2 2 2 1 Multicopper oxidase SLD5_C PF16922.5 KKK22218.1 - 4.7e-13 49.1 1.8 7.7e-13 48.4 1.8 1.4 1 0 0 1 1 1 1 DNA replication complex GINS protein SLD5 C-terminus Sld5 PF05916.11 KKK22218.1 - 9.2e-11 42.2 1.0 1.5e-10 41.5 1.0 1.4 1 0 0 1 1 1 1 GINS complex protein FlaF PF07309.11 KKK22218.1 - 0.022 14.7 1.8 0.038 14.0 1.8 1.3 1 0 0 1 1 1 0 Flagellar protein FlaF ILVD_EDD PF00920.21 KKK22218.1 - 0.032 12.9 0.5 0.17 10.5 0.1 1.9 2 0 0 2 2 2 0 Dehydratase family Foie-gras_1 PF11817.8 KKK22218.1 - 0.12 11.9 2.5 0.17 11.4 2.5 1.2 1 0 0 1 1 1 0 Foie gras liver health family 1 Rhodanese PF00581.20 KKK22219.1 - 2.5e-12 47.2 0.0 5.7e-12 46.1 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain zf-DNL PF05180.12 KKK22220.1 - 1.4e-28 98.6 0.5 2.1e-28 98.0 0.5 1.3 1 0 0 1 1 1 1 DNL zinc finger DUF2039 PF10217.9 KKK22220.1 - 0.0092 16.3 0.6 0.015 15.6 0.6 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2039) zinc_ribbon_4 PF13717.6 KKK22220.1 - 0.023 14.6 0.8 0.14 12.1 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain Elf1 PF05129.13 KKK22220.1 - 0.029 14.4 0.6 0.065 13.3 0.6 1.5 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like HypA PF01155.19 KKK22220.1 - 0.046 13.7 1.6 0.12 12.4 1.6 1.8 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-CSL PF05207.13 KKK22220.1 - 0.064 13.0 0.5 0.13 12.0 0.5 1.5 1 0 0 1 1 1 0 CSL zinc finger E7 PF00527.18 KKK22220.1 - 0.25 11.6 5.3 0.14 12.4 1.8 2.2 1 1 1 2 2 2 0 E7 protein, Early protein TFIIS_C PF01096.18 KKK22220.1 - 1.7 8.6 5.8 12 5.9 0.1 2.8 3 1 0 3 3 3 0 Transcription factor S-II (TFIIS) Zn_ribbon_SprT PF17283.2 KKK22220.1 - 1.8 8.6 7.7 1.1 9.2 4.8 2.1 2 1 1 3 3 3 0 SprT-like zinc ribbon domain Zn_Tnp_IS1595 PF12760.7 KKK22220.1 - 4.2 7.4 7.1 9.1 6.3 1.0 2.4 1 1 1 2 2 2 0 Transposase zinc-ribbon domain Cullin PF00888.22 KKK22221.1 - 5.9e-202 672.6 13.3 7.6e-202 672.2 13.3 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 KKK22221.1 - 2.2e-25 88.4 0.9 8.1e-25 86.6 0.9 2.1 1 0 0 1 1 1 1 Cullin protein neddylation domain CwfJ_C_2 PF04676.14 KKK22222.1 - 1.6e-13 51.3 0.1 3.2e-13 50.4 0.1 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 CwfJ_C_1 PF04677.15 KKK22222.1 - 8.7e-10 38.5 0.0 1.4e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 DRIM PF07539.12 KKK22223.1 - 8.7e-197 655.2 0.5 8.7e-197 655.2 0.5 2.4 3 0 0 3 3 3 1 Down-regulated in metastasis HEAT PF02985.22 KKK22223.1 - 0.00055 20.0 4.0 2.2 8.8 0.0 7.1 8 0 0 8 8 8 1 HEAT repeat DUF4556 PF15094.6 KKK22223.1 - 0.14 11.4 0.3 0.3 10.3 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4556) Corona_S2 PF01601.16 KKK22224.1 - 0.17 10.3 10.0 0.23 9.9 10.0 1.1 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein DNA_pol_phi PF04931.13 KKK22225.1 - 2.8e-239 796.2 35.4 1.5e-237 790.5 35.4 2.1 1 1 0 1 1 1 1 DNA polymerase phi DUF445 PF04286.12 KKK22225.1 - 0.4 10.4 9.1 0.77 9.5 0.1 3.2 2 1 0 3 3 3 0 Protein of unknown function (DUF445) SDA1 PF05285.12 KKK22225.1 - 3.8 6.8 26.1 1.1 8.6 21.9 2.0 2 0 0 2 2 2 0 SDA1 CAP59_mtransfer PF11735.8 KKK22227.1 - 4.3e-76 255.8 0.0 5.6e-76 255.4 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 HSP90 PF00183.18 KKK22228.1 - 3.8e-222 738.8 33.2 4.9e-222 738.4 33.2 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 KKK22228.1 - 6.1e-15 55.7 0.1 1.1e-14 54.8 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KKK22228.1 - 1.5e-09 37.8 0.1 1.5e-09 37.8 0.1 2.5 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase LOH1CR12 PF10158.9 KKK22228.1 - 0.045 13.8 0.4 0.25 11.4 0.2 2.4 2 0 0 2 2 2 0 Tumour suppressor protein Rad54_N PF08658.10 KKK22228.1 - 0.45 10.6 9.7 0.43 10.7 0.2 2.8 2 0 0 2 2 2 0 Rad54 N terminal DUF1676 PF07898.13 KKK22228.1 - 1 9.3 5.1 0.63 10.1 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1676) Cofac_haem_bdg PF04187.13 KKK22228.1 - 1.2 9.1 4.6 2.6 8.0 0.0 2.9 3 1 1 4 4 4 0 Haem-binding uptake, Tiki superfamily, ChaN NTF2 PF02136.20 KKK22229.1 - 4.6e-27 95.0 0.7 7.5e-27 94.3 0.7 1.4 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.22 KKK22229.1 - 2.6e-09 36.8 0.1 4.6e-09 36.0 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KKK22229.1 - 0.12 12.3 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 Occluded RNA-recognition motif Pkinase PF00069.25 KKK22232.1 - 6.6e-61 206.0 0.0 1.7e-60 204.6 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK22232.1 - 5.4e-28 98.0 0.0 1.2e-27 96.9 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KKK22232.1 - 1.4e-05 24.3 0.1 1.8e-05 23.9 0.1 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KKK22232.1 - 0.00021 20.7 0.1 0.00069 19.0 0.1 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KKK22232.1 - 0.0011 19.0 0.0 0.0027 17.7 0.0 1.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KKK22232.1 - 0.016 14.6 0.0 0.063 12.6 0.0 1.9 1 1 1 2 2 2 0 Kinase-like FTA2 PF13095.6 KKK22232.1 - 0.016 14.8 0.0 0.03 14.0 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 KKK22232.1 - 0.053 13.1 0.0 0.083 12.5 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Avl9 PF09794.9 KKK22233.1 - 1.8e-137 458.1 0.1 3.5e-121 404.5 0.0 2.2 2 0 0 2 2 2 2 Transport protein Avl9 SPA PF08616.10 KKK22233.1 - 2.2e-09 37.3 0.1 3.3e-05 23.8 0.0 2.4 2 0 0 2 2 2 2 Stabilization of polarity axis DUF2347 PF09804.9 KKK22233.1 - 0.54 9.8 11.2 0.063 12.9 0.3 3.1 3 1 0 3 3 3 0 Uncharacterized conserved protein (DUF2347) Uds1 PF15456.6 KKK22233.1 - 7.5 6.7 9.6 0.68 10.1 2.6 2.4 2 0 0 2 2 2 0 Up-regulated During Septation zf-RING_2 PF13639.6 KKK22234.1 - 6.9e-10 39.1 4.0 1.1e-09 38.4 4.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 KKK22234.1 - 2.1e-08 33.9 1.6 3.3e-08 33.3 1.6 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KKK22234.1 - 1.7e-07 30.9 4.0 2.7e-07 30.3 4.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KKK22234.1 - 2.8e-07 30.7 1.7 6.8e-07 29.5 1.7 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KKK22234.1 - 3.3e-07 30.1 2.7 5.2e-07 29.4 2.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KKK22234.1 - 0.0022 17.8 3.5 0.0036 17.1 3.5 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 KKK22234.1 - 0.0088 16.0 2.7 0.02 14.9 2.7 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KKK22234.1 - 0.17 11.9 1.6 0.32 11.0 1.6 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KKK22234.1 - 0.25 11.6 4.5 0.45 10.7 4.5 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_11 PF17123.5 KKK22234.1 - 0.25 11.1 1.7 0.57 10.0 1.7 1.6 1 0 0 1 1 1 0 RING-like zinc finger HAD_SAK_1 PF10307.9 KKK22235.1 - 2e-79 266.1 0.0 2.8e-79 265.7 0.0 1.2 1 0 0 1 1 1 1 HAD domain family 1 in Swiss Army Knife RNA repair proteins API5 PF05918.11 KKK22235.1 - 4 6.1 4.6 6.4 5.5 4.6 1.3 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Drc1-Sld2 PF11719.8 KKK22236.1 - 1.3e-137 460.0 24.3 1.3e-137 460.0 24.3 1.6 2 0 0 2 2 2 1 DNA replication and checkpoint protein Suc_Fer-like PF06999.12 KKK22236.1 - 8.5e-65 218.3 0.0 1.5e-64 217.4 0.0 1.4 1 0 0 1 1 1 1 Sucrase/ferredoxin-like Zn_clus PF00172.18 KKK22237.1 - 5.5e-10 39.2 8.7 9.1e-10 38.5 8.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain VIT1 PF01988.19 KKK22238.1 - 9.6e-64 215.2 2.7 1.2e-63 214.9 2.7 1.1 1 0 0 1 1 1 1 VIT family SLATT_fungal PF18142.1 KKK22238.1 - 0.11 12.5 0.0 0.27 11.2 0.0 1.7 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain Phosphoesterase PF04185.14 KKK22239.1 - 4.8e-56 190.5 6.8 8.2e-56 189.7 6.8 1.4 1 1 0 1 1 1 1 Phosphoesterase family FAM219A PF15260.6 KKK22241.1 - 0.15 12.4 2.7 0.38 11.1 2.7 1.6 1 0 0 1 1 1 0 Protein family FAM219A SKG6 PF08693.10 KKK22241.1 - 0.96 8.9 2.8 2.8 7.4 2.8 1.9 1 1 0 1 1 1 0 Transmembrane alpha-helix domain AF-4 PF05110.13 KKK22241.1 - 1.7 6.6 10.6 2.1 6.3 10.6 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein AP_endonuc_2 PF01261.24 KKK22242.1 - 2.9e-15 56.3 0.1 4.7e-15 55.6 0.1 1.4 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel DSPc PF00782.20 KKK22245.1 - 0.0098 15.7 0.0 0.013 15.3 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PAXX PF15384.6 KKK22245.1 - 0.14 11.8 0.2 0.2 11.3 0.2 1.2 1 0 0 1 1 1 0 PAXX, PAralog of XRCC4 and XLF, also called C9orf142 Zn_clus PF00172.18 KKK22246.1 - 8.5e-08 32.2 10.7 1.5e-07 31.4 10.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KKK22246.1 - 3.1e-06 26.4 1.2 3.1e-06 26.4 1.2 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain APH PF01636.23 KKK22247.1 - 0.047 13.6 0.4 0.17 11.8 0.2 1.8 2 1 0 2 2 2 0 Phosphotransferase enzyme family RTA1 PF04479.13 KKK22249.1 - 4.6e-38 130.9 5.5 5.9e-38 130.5 5.5 1.1 1 0 0 1 1 1 1 RTA1 like protein adh_short_C2 PF13561.6 KKK22250.1 - 6.9e-44 150.1 0.1 2.7e-43 148.2 0.1 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KKK22250.1 - 1.9e-31 109.0 0.2 7.5e-31 107.1 0.2 2.0 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KKK22250.1 - 0.00015 21.8 0.1 0.00025 21.0 0.1 1.4 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KKK22250.1 - 0.038 13.1 0.0 0.053 12.7 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein PIF PF05092.12 KKK22250.1 - 0.039 12.7 0.2 0.055 12.2 0.2 1.1 1 0 0 1 1 1 0 Per os infectivity Aa_trans PF01490.18 KKK22251.1 - 6.8e-62 209.5 19.4 5.4e-54 183.5 13.7 2.0 1 1 1 2 2 2 2 Transmembrane amino acid transporter protein EFTUD2 PF16004.5 KKK22251.1 - 0.036 14.6 0.7 0.036 14.6 0.7 1.5 2 0 0 2 2 2 0 116 kDa U5 small nuclear ribonucleoprotein component N-terminus Zn_clus PF00172.18 KKK22252.1 - 2.3e-09 37.2 12.4 3.8e-09 36.5 12.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pectinesterase PF01095.19 KKK22253.1 - 3.1e-52 177.2 5.9 3.9e-52 176.8 5.9 1.0 1 0 0 1 1 1 1 Pectinesterase AA_permease_2 PF13520.6 KKK22254.1 - 9.9e-49 166.3 42.9 1.3e-48 166.0 42.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KKK22254.1 - 6.4e-23 81.1 38.3 8.7e-23 80.6 38.3 1.1 1 0 0 1 1 1 1 Amino acid permease SID-1_RNA_chan PF13965.6 KKK22254.1 - 0.0014 17.1 0.2 0.0014 17.1 0.2 1.9 2 0 0 2 2 2 1 dsRNA-gated channel SID-1 PTR2 PF00854.21 KKK22255.1 - 1.7e-45 155.5 0.5 2.4e-45 155.0 0.5 1.1 1 0 0 1 1 1 1 POT family ketoacyl-synt PF00109.26 KKK22256.1 - 1.6e-71 240.8 0.0 1.8e-71 240.7 0.0 1.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Thiolase_N PF00108.23 KKK22256.1 - 6.1e-06 25.8 0.1 9.7e-06 25.1 0.1 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain ACP_syn_III PF08545.10 KKK22256.1 - 0.00076 19.3 2.1 0.002 18.0 2.1 1.8 1 1 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III adh_short_C2 PF13561.6 KKK22257.1 - 6.7e-55 186.2 3.0 9.4e-55 185.7 3.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KKK22257.1 - 3.2e-42 144.2 2.3 4.5e-42 143.7 2.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KKK22257.1 - 2.1e-06 27.8 0.7 5e-06 26.5 0.7 1.6 1 1 0 1 1 1 1 KR domain Ldh_1_N PF00056.23 KKK22257.1 - 0.13 12.4 0.1 0.23 11.5 0.1 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 KKK22258.1 - 3e-26 92.5 0.2 1.1e-14 54.5 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_3 PF13738.6 KKK22258.1 - 1.1e-06 28.1 0.3 9.3e-06 25.1 0.1 2.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KKK22258.1 - 1.3e-06 27.9 2.3 0.0014 18.0 0.4 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KKK22258.1 - 9.6e-06 25.7 1.3 6.4e-05 23.1 0.3 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 KKK22258.1 - 1.2e-05 24.9 2.3 0.017 14.4 0.0 2.7 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 KKK22258.1 - 1.7e-05 24.1 1.0 3e-05 23.3 1.0 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KKK22258.1 - 0.00027 20.7 1.4 0.0025 17.5 2.1 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KKK22258.1 - 0.0017 17.5 0.8 0.49 9.4 0.8 2.3 2 0 0 2 2 2 2 Lycopene cyclase protein Pyr_redox PF00070.27 KKK22258.1 - 0.0033 18.0 1.8 0.028 15.0 0.4 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KKK22258.1 - 0.0083 14.9 0.3 0.015 14.1 0.3 1.4 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.17 KKK22258.1 - 0.011 15.0 0.3 0.02 14.1 0.3 1.3 1 0 0 1 1 1 0 Thi4 family GIDA PF01134.22 KKK22258.1 - 0.012 14.7 1.4 0.018 14.2 1.4 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 KKK22258.1 - 0.035 13.4 0.3 0.066 12.5 0.3 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Trp_halogenase PF04820.14 KKK22258.1 - 0.076 11.9 2.3 0.38 9.6 0.3 2.2 2 0 0 2 2 2 0 Tryptophan halogenase NAD_binding_9 PF13454.6 KKK22258.1 - 0.13 12.2 1.8 7.8 6.5 0.0 3.6 3 1 1 4 4 4 0 FAD-NAD(P)-binding FAD_oxidored PF12831.7 KKK22258.1 - 0.66 9.3 3.0 0.4 10.0 1.3 1.5 2 0 0 2 2 2 0 FAD dependent oxidoreductase zf-C2H2 PF00096.26 KKK22261.1 - 5.8e-07 29.6 15.6 0.0041 17.5 3.2 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KKK22261.1 - 0.00017 21.9 12.5 0.00075 19.8 1.6 3.8 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KKK22261.1 - 0.0052 17.5 14.1 0.53 11.3 2.7 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger SOCS PF12610.8 KKK22261.1 - 0.25 11.8 4.8 9.9 6.6 0.4 2.8 2 1 0 2 2 2 0 Suppressor of cytokine signalling zf-met PF12874.7 KKK22261.1 - 0.44 11.0 4.5 1.1 9.8 2.2 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KKK22261.1 - 1.8 8.6 6.6 0.25 11.4 2.0 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger FAD_binding_4 PF01565.23 KKK22263.1 - 4.7e-19 68.5 0.1 9.8e-19 67.5 0.1 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KKK22263.1 - 5.5e-09 36.0 0.3 1.4e-08 34.7 0.3 1.7 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.10 KKK22263.1 - 0.11 11.9 0.1 0.17 11.3 0.1 1.2 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding Ecm33 PF12454.8 KKK22263.1 - 1.6 9.0 5.6 7.6 6.8 3.5 2.6 2 0 0 2 2 2 0 GPI-anchored cell wall organization protein Pro-kuma_activ PF09286.11 KKK22264.1 - 1.2e-30 106.7 0.2 2.4e-29 102.5 0.0 2.7 3 0 0 3 3 3 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 KKK22264.1 - 0.0063 15.8 0.0 0.016 14.5 0.0 1.6 1 1 0 1 1 1 1 Subtilase family GPI-anchored PF10342.9 KKK22265.1 - 1.4e-19 70.6 2.6 1.4e-19 70.6 2.6 2.2 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF1593 PF07632.11 KKK22266.1 - 3.2e-74 249.6 0.0 5.1e-74 249.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1593) ArabFuran-catal PF09206.11 KKK22267.1 - 4.8e-135 449.9 10.7 4.8e-135 449.9 10.7 1.4 2 0 0 2 2 2 1 Alpha-L-arabinofuranosidase B, catalytic AbfB PF05270.13 KKK22267.1 - 4.6e-59 198.4 2.7 6.8e-59 197.9 2.7 1.3 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase B (ABFB) domain FMO-like PF00743.19 KKK22268.1 - 3.8e-16 58.6 0.0 1.8e-14 53.1 0.0 2.4 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 KKK22268.1 - 2.6e-09 37.2 0.0 1.8e-08 34.5 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KKK22268.1 - 8.1e-07 28.6 0.0 0.0002 20.7 0.0 2.3 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KKK22268.1 - 5e-06 25.9 0.0 0.0004 19.6 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 KKK22268.1 - 4e-05 23.0 0.0 0.023 14.0 0.0 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KKK22268.1 - 4.5e-05 23.2 0.1 1.1 8.7 0.0 3.2 2 1 1 3 3 3 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KKK22268.1 - 0.052 13.5 0.3 1.3 9.0 0.0 3.1 4 0 0 4 4 4 0 FAD-NAD(P)-binding LBR_tudor PF09465.10 KKK22268.1 - 0.084 12.7 0.1 0.21 11.4 0.1 1.6 1 0 0 1 1 1 0 Lamin-B receptor of TUDOR domain Thi4 PF01946.17 KKK22268.1 - 0.091 12.0 0.0 0.19 10.9 0.0 1.4 1 0 0 1 1 1 0 Thi4 family CVNH PF08881.10 KKK22269.1 - 6.4e-27 94.2 0.6 8.9e-27 93.7 0.6 1.2 1 0 0 1 1 1 1 CVNH domain Rick_17kDa_Anti PF05433.15 KKK22269.1 - 8.6e-07 28.7 13.6 1.3e-06 28.1 13.6 1.3 1 0 0 1 1 1 1 Glycine zipper 2TM domain DUF2076 PF09849.9 KKK22269.1 - 0.00037 20.6 4.7 0.00057 20.0 4.7 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) Gly-zipper_Omp PF13488.6 KKK22269.1 - 0.0011 18.9 9.0 0.0018 18.3 9.0 1.3 1 0 0 1 1 1 1 Glycine zipper TraT PF05818.12 KKK22269.1 - 0.0081 15.9 0.2 0.013 15.2 0.2 1.2 1 0 0 1 1 1 1 Enterobacterial TraT complement resistance protein DUF533 PF04391.12 KKK22269.1 - 0.027 14.1 0.0 0.043 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF533) Transgly_assoc PF04226.13 KKK22269.1 - 3.3 8.0 10.9 5 7.5 10.9 1.3 1 0 0 1 1 1 0 Transglycosylase associated protein MFS_1 PF07690.16 KKK22271.1 - 8e-11 41.5 45.9 3.5e-10 39.3 41.7 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KKK22271.1 - 4.5e-09 35.3 10.6 4.5e-09 35.3 10.6 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF3439 PF11921.8 KKK22271.1 - 8.1 6.4 9.4 18 5.3 9.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Abhydrolase_3 PF07859.13 KKK22272.1 - 1.7e-46 158.8 0.1 2.1e-46 158.5 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.20 KKK22272.1 - 0.00057 20.1 0.0 0.00072 19.7 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Say1_Mug180 PF10340.9 KKK22272.1 - 0.0016 17.4 0.0 0.0022 16.9 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase Hydrolase_4 PF12146.8 KKK22272.1 - 0.0056 16.0 0.0 0.013 14.7 0.0 1.6 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KKK22272.1 - 0.011 15.4 0.0 0.015 15.0 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Dabb PF07876.12 KKK22273.1 - 4.6e-08 33.6 0.0 6.6e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain DUF1729 PF08354.10 KKK22274.1 - 2.4e-142 474.0 0.0 2.5e-141 470.7 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1729) Acyl_transf_1 PF00698.21 KKK22274.1 - 4.2e-87 292.6 0.2 4.8e-84 282.6 0.0 3.0 2 1 1 3 3 3 2 Acyl transferase domain MaoC_dehydratas PF01575.19 KKK22274.1 - 2.9e-26 91.4 0.0 6.8e-26 90.3 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain SAT PF16073.5 KKK22274.1 - 8.8e-21 74.7 0.2 1.9e-20 73.6 0.2 1.5 1 0 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis FAS_meander PF17951.1 KKK22274.1 - 2.3e-11 43.7 0.0 4.2e-11 42.8 0.0 1.5 1 0 0 1 1 1 1 Fatty acid synthase meander beta sheet domain MaoC_dehydrat_N PF13452.6 KKK22274.1 - 3.5e-09 36.9 0.1 6e-08 32.9 0.0 2.4 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase Fas_alpha_ACP PF18325.1 KKK22275.1 - 1.3e-47 162.1 0.0 2.7e-47 161.1 0.0 1.6 1 0 0 1 1 1 1 Fatty acid synthase subunit alpha Acyl carrier domain ketoacyl-synt PF00109.26 KKK22275.1 - 1.5e-26 93.5 0.2 3.4e-26 92.3 0.2 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain FAS_I_H PF18314.1 KKK22275.1 - 3.5e-26 92.1 0.6 2.6e-25 89.2 0.6 2.1 1 1 0 1 1 1 1 Fatty acid synthase type I helical domain Ketoacyl-synt_C PF02801.22 KKK22275.1 - 3.6e-14 52.8 0.0 9.9e-14 51.4 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ACPS PF01648.20 KKK22275.1 - 1.4e-11 44.5 0.0 3.7e-11 43.2 0.0 1.8 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily adh_short PF00106.25 KKK22275.1 - 1.4e-05 24.7 0.0 0.00011 21.8 0.0 2.3 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 KKK22275.1 - 2e-05 24.6 0.0 5.6e-05 23.1 0.0 1.8 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 KKK22275.1 - 6.8e-05 22.5 0.0 0.00014 21.5 0.0 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase GDP_Man_Dehyd PF16363.5 KKK22275.1 - 0.0056 16.1 0.0 0.0087 15.5 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase adh_short PF00106.25 KKK22276.1 - 4.4e-22 78.5 0.0 6e-22 78.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KKK22276.1 - 6.9e-15 55.2 0.1 6.4e-14 52.1 0.1 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 KKK22276.1 - 0.097 12.1 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DNA_pol_lambd_f PF10391.9 KKK22276.1 - 0.16 11.9 0.1 0.37 10.7 0.1 1.6 1 0 0 1 1 1 0 Fingers domain of DNA polymerase lambda KR PF08659.10 KKK22276.1 - 0.74 9.7 6.3 3.1 7.7 1.6 3.3 3 1 0 3 3 3 0 KR domain p450 PF00067.22 KKK22277.1 - 1.1e-62 212.3 0.0 1.4e-62 211.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF1772 PF08592.11 KKK22278.1 - 1.6e-29 103.0 3.1 1.9e-29 102.7 3.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) p450 PF00067.22 KKK22279.1 - 8e-59 199.6 0.0 2.5e-56 191.3 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 NAD_binding_10 PF13460.6 KKK22280.1 - 2.1e-12 47.3 0.0 6e-12 45.8 0.0 1.7 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KKK22280.1 - 4.7e-06 26.3 0.0 2.3e-05 24.0 0.0 1.9 2 0 0 2 2 2 1 NmrA-like family NAD_binding_4 PF07993.12 KKK22280.1 - 0.012 14.8 0.1 0.018 14.2 0.1 1.2 1 0 0 1 1 1 0 Male sterility protein Semialdhyde_dh PF01118.24 KKK22280.1 - 0.034 14.6 0.0 0.059 13.8 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 KKK22280.1 - 0.038 14.3 0.0 0.073 13.3 0.0 1.5 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain GMC_oxred_N PF00732.19 KKK22281.1 - 2.8e-52 177.9 0.0 3.7e-52 177.5 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KKK22281.1 - 1.5e-34 119.6 0.0 2.4e-34 118.9 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_3 PF13738.6 KKK22281.1 - 1.8e-07 30.8 0.2 0.0077 15.5 0.4 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KKK22281.1 - 5.5e-07 29.0 1.6 9.6e-05 21.6 1.3 2.1 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 KKK22281.1 - 2e-06 27.7 2.7 3e-05 23.8 2.7 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KKK22281.1 - 0.00017 21.8 0.0 0.00046 20.4 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KKK22281.1 - 0.00042 19.6 0.1 0.37 10.0 0.1 2.2 2 0 0 2 2 2 2 Thi4 family Pyr_redox_2 PF07992.14 KKK22281.1 - 0.00043 19.6 0.7 0.0038 16.5 0.3 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KKK22281.1 - 0.001 18.2 0.3 0.0015 17.6 0.3 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Trp_halogenase PF04820.14 KKK22281.1 - 0.043 12.7 0.0 0.062 12.1 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase FAD_binding_3 PF01494.19 KKK22281.1 - 0.043 13.1 0.2 0.082 12.1 0.2 1.4 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.27 KKK22281.1 - 0.064 13.8 2.5 1.5 9.4 0.6 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KKK22281.1 - 0.093 12.7 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding TrkA_N PF02254.18 KKK22281.1 - 0.098 12.9 0.6 0.21 11.9 0.1 1.8 2 0 0 2 2 2 0 TrkA-N domain Questin_oxidase PF14027.6 KKK22282.1 - 3.6e-88 296.4 0.0 4.5e-88 296.0 0.0 1.1 1 0 0 1 1 1 1 Questin oxidase-like DUF433 PF04255.14 KKK22282.1 - 0.027 14.3 0.0 0.084 12.7 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF433) FAD_binding_4 PF01565.23 KKK22284.1 - 1.6e-19 70.0 1.8 2.9e-19 69.2 1.8 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KKK22284.1 - 1.8e-06 27.9 0.0 4.8e-06 26.6 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like Maf PF02545.14 KKK22284.1 - 0.016 15.0 0.0 0.03 14.2 0.0 1.4 1 0 0 1 1 1 0 Maf-like protein TyeA PF09059.10 KKK22284.1 - 0.067 13.3 0.0 0.18 12.0 0.0 1.6 2 0 0 2 2 2 0 TyeA Methyltransf_2 PF00891.18 KKK22285.1 - 1.3e-23 83.4 0.0 3.4e-23 82.1 0.0 1.7 1 0 0 1 1 1 1 O-methyltransferase domain NAD_binding_10 PF13460.6 KKK22285.1 - 7e-20 71.7 0.0 1.1e-19 71.1 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KKK22285.1 - 4.3e-06 26.4 0.1 8.7e-06 25.5 0.1 1.5 1 0 0 1 1 1 1 NmrA-like family Dimerisation2 PF16864.5 KKK22285.1 - 7.5e-05 22.6 0.1 0.00027 20.8 0.0 1.9 2 0 0 2 2 2 1 Dimerisation domain Epimerase PF01370.21 KKK22285.1 - 0.00014 21.4 0.0 0.00023 20.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KKK22285.1 - 0.013 14.6 0.0 0.018 14.0 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Dimerisation PF08100.11 KKK22285.1 - 0.014 15.4 0.0 0.041 13.9 0.0 1.8 1 0 0 1 1 1 0 Dimerisation domain Semialdhyde_dh PF01118.24 KKK22285.1 - 0.034 14.6 0.0 0.068 13.6 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain AflR PF08493.10 KKK22286.1 - 1.6e-65 221.5 4.5 1.6e-65 221.5 4.5 1.9 1 1 1 2 2 1 1 Aflatoxin regulatory protein TFIIA PF03153.13 KKK22286.1 - 0.0031 17.6 31.7 0.0042 17.1 31.7 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF4045 PF13254.6 KKK22286.1 - 0.017 14.8 14.2 0.023 14.3 14.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) CDC45 PF02724.14 KKK22286.1 - 0.022 13.1 11.1 0.028 12.7 11.1 1.1 1 0 0 1 1 1 0 CDC45-like protein TP53IP5 PF15331.6 KKK22286.1 - 0.047 13.9 8.7 0.071 13.3 8.7 1.2 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 Presenilin PF01080.17 KKK22286.1 - 0.079 11.7 21.1 0.12 11.2 21.1 1.2 1 0 0 1 1 1 0 Presenilin MMR1 PF08505.10 KKK22286.1 - 0.099 12.9 15.9 0.14 12.4 15.9 1.2 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein DUF913 PF06025.12 KKK22286.1 - 0.11 11.5 6.2 0.17 10.8 6.2 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Lin-8 PF03353.15 KKK22286.1 - 0.13 11.8 19.8 0.2 11.2 19.8 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Sin_N PF04801.13 KKK22286.1 - 0.15 11.3 19.3 0.21 10.8 19.3 1.2 1 0 0 1 1 1 0 Sin-like protein conserved region Plasmodium_Vir PF05795.11 KKK22286.1 - 0.19 11.1 6.9 0.27 10.6 6.9 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein RR_TM4-6 PF06459.12 KKK22286.1 - 0.33 10.7 18.9 0.52 10.1 18.9 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CobT PF06213.12 KKK22286.1 - 0.34 10.2 28.7 0.56 9.5 28.7 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT SARAF PF06682.12 KKK22286.1 - 0.37 10.4 13.4 0.97 9.0 13.7 1.5 2 0 0 2 2 1 0 SOCE-associated regulatory factor of calcium homoeostasis SRP-alpha_N PF04086.13 KKK22286.1 - 0.41 10.5 15.6 0.57 10.1 15.6 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Spore_coat_CotO PF14153.6 KKK22286.1 - 0.46 10.4 24.0 0.71 9.8 24.0 1.2 1 0 0 1 1 1 0 Spore coat protein CotO PAT1 PF09770.9 KKK22286.1 - 0.58 8.4 27.1 0.76 8.0 27.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Otopetrin PF03189.13 KKK22286.1 - 0.58 8.9 1.7 0.64 8.8 1.7 1.2 1 0 0 1 1 1 0 Otopetrin SLC12 PF03522.15 KKK22286.1 - 0.62 9.0 15.8 0.85 8.6 15.8 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Macoilin PF09726.9 KKK22286.1 - 0.74 8.3 11.0 0.96 7.9 11.0 1.1 1 0 0 1 1 1 0 Macoilin family GREB1 PF15782.5 KKK22286.1 - 0.8 6.7 14.5 1.1 6.3 14.5 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer V_ATPase_I PF01496.19 KKK22286.1 - 0.83 7.5 15.9 1.2 7.0 15.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FAM60A PF15396.6 KKK22286.1 - 1.1 9.3 10.4 1.7 8.6 10.4 1.2 1 0 0 1 1 1 0 Protein Family FAM60A CCSAP PF15748.5 KKK22286.1 - 1.3 9.2 21.8 1.8 8.6 21.8 1.2 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated SAPS PF04499.15 KKK22286.1 - 1.6 7.4 11.8 2.3 6.9 11.8 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein 5_nucleotid PF05761.14 KKK22286.1 - 2.6 6.9 8.0 3.6 6.4 8.0 1.1 1 0 0 1 1 1 0 5' nucleotidase family Rtf2 PF04641.12 KKK22286.1 - 2.7 7.3 14.0 3.8 6.8 14.0 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger CNDH2_M PF16869.5 KKK22286.1 - 3.3 8.4 15.2 6.1 7.5 15.2 1.4 1 0 0 1 1 1 0 PF16858 Ndc1_Nup PF09531.10 KKK22286.1 - 3.8 6.1 8.9 5.1 5.7 8.9 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Endostatin PF06482.11 KKK22286.1 - 4.3 6.7 15.5 6.6 6.1 15.5 1.2 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin Gti1_Pac2 PF09729.9 KKK22286.1 - 5.5 7.0 13.0 9.6 6.3 13.0 1.4 1 0 0 1 1 1 0 Gti1/Pac2 family Serinc PF03348.15 KKK22286.1 - 6.7 5.5 6.8 11 4.9 6.8 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) SID-1_RNA_chan PF13965.6 KKK22286.1 - 6.8 5.0 5.1 12 4.2 5.1 1.3 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Suf PF05843.14 KKK22286.1 - 7.9 6.4 18.7 5.5e+02 0.3 22.3 2.0 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Tim54 PF11711.8 KKK22286.1 - 8.7 5.0 15.2 16 4.2 15.2 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Peroxidase_2 PF01328.17 KKK22288.1 - 7.2e-51 173.4 0.0 9e-51 173.1 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 DUF4267 PF14087.6 KKK22289.1 - 9.4e-28 96.5 2.8 1.9e-27 95.5 2.8 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) adh_short PF00106.25 KKK22289.1 - 4.4e-13 49.1 0.1 1e-12 48.0 0.1 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KKK22289.1 - 1e-11 44.9 0.0 1.4e-11 44.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase UT PF03253.14 KKK22289.1 - 0.019 14.1 2.8 0.028 13.6 2.8 1.3 1 0 0 1 1 1 0 Urea transporter DUF5453 PF17534.2 KKK22289.1 - 0.11 12.4 0.1 0.49 10.3 0.0 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5453) Epimerase PF01370.21 KKK22289.1 - 0.13 11.7 0.1 0.24 10.8 0.1 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family ketoacyl-synt PF00109.26 KKK22290.1 - 1.9e-80 270.1 0.0 4.3e-80 268.9 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain SAT PF16073.5 KKK22290.1 - 5.2e-71 239.2 0.7 1.1e-70 238.1 0.1 1.9 2 0 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Thioesterase PF00975.20 KKK22290.1 - 4.1e-43 148.1 0.0 2.9e-41 142.1 0.0 2.5 2 0 0 2 2 2 1 Thioesterase domain Acyl_transf_1 PF00698.21 KKK22290.1 - 3.7e-38 131.8 0.0 1.6e-36 126.5 0.0 2.4 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KKK22290.1 - 1.8e-34 118.2 0.1 4.1e-34 117.1 0.1 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.25 KKK22290.1 - 2e-18 66.5 11.3 3.7e-10 40.0 0.8 2.8 3 0 0 3 3 3 2 Phosphopantetheine attachment site PS-DH PF14765.6 KKK22290.1 - 7.9e-16 58.2 0.0 1.3e-15 57.5 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase KAsynt_C_assoc PF16197.5 KKK22290.1 - 2.7e-08 34.2 0.0 6.2e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Thiolase_N PF00108.23 KKK22290.1 - 0.002 17.6 0.4 0.0045 16.4 0.0 1.8 2 0 0 2 2 2 1 Thiolase, N-terminal domain Abhydrolase_6 PF12697.7 KKK22290.1 - 0.0075 16.9 5.9 0.49 10.9 0.0 3.9 4 0 0 4 4 4 2 Alpha/beta hydrolase family p450 PF00067.22 KKK22291.1 - 9.8e-56 189.4 0.0 1.4e-55 188.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 EthD PF07110.11 KKK22292.1 - 4.2e-17 63.1 0.3 5e-17 62.8 0.3 1.1 1 0 0 1 1 1 1 EthD domain MmlI PF09448.10 KKK22292.1 - 0.00061 20.2 0.0 0.00098 19.6 0.0 1.4 1 1 0 1 1 1 1 Methylmuconolactone methyl-isomerase p450 PF00067.22 KKK22293.1 - 1.1e-53 182.6 0.0 1.6e-53 182.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Aldo_ket_red PF00248.21 KKK22294.1 - 1.2e-63 215.1 0.0 1.7e-63 214.5 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family adh_short_C2 PF13561.6 KKK22294.1 - 1.2e-58 198.4 1.8 2e-58 197.7 1.8 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KKK22294.1 - 3e-50 170.4 0.4 4.5e-50 169.8 0.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KKK22294.1 - 1.2e-15 57.9 0.2 2.3e-15 57.0 0.2 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KKK22294.1 - 0.0043 16.5 0.2 0.0091 15.5 0.1 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family GST_N PF02798.20 KKK22295.1 - 4.3e-13 49.4 0.0 9.7e-13 48.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KKK22295.1 - 2.6e-12 46.8 0.0 4e-12 46.2 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KKK22295.1 - 1.5e-07 31.7 0.0 3.4e-07 30.6 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KKK22295.1 - 1.3e-06 28.6 0.0 2.8e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KKK22295.1 - 1.9e-05 24.9 0.0 6.1e-05 23.2 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KKK22295.1 - 9.1e-05 22.4 0.1 0.00021 21.3 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Big_3 PF07523.12 KKK22295.1 - 0.082 13.2 0.0 0.16 12.3 0.0 1.4 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 3) zf-BED PF02892.15 KKK22296.1 - 0.0031 17.5 2.7 0.024 14.6 0.1 2.6 2 0 0 2 2 2 1 BED zinc finger Phage_clamp_A PF16790.5 KKK22296.1 - 0.063 13.7 0.0 0.11 12.9 0.0 1.3 1 0 0 1 1 1 0 Bacteriophage clamp loader A subunit zf-C2H2_4 PF13894.6 KKK22303.1 - 0.36 11.8 11.7 0.74 10.8 1.3 3.9 3 0 0 3 3 3 0 C2H2-type zinc finger YpzG PF14139.6 KKK22303.1 - 0.39 10.9 4.5 0.12 12.6 0.8 2.0 2 0 0 2 2 2 0 YpzG-like protein ATP_sub_h PF10775.9 KKK22311.1 - 3.9e-27 94.0 0.4 7.8e-27 93.1 0.4 1.5 1 0 0 1 1 1 1 ATP synthase complex subunit h ATP-synt_F6 PF05511.11 KKK22311.1 - 0.042 14.3 0.0 0.084 13.3 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial ATP synthase coupling factor 6 DUF1765 PF08578.10 KKK22312.1 - 1.6e-43 148.1 7.8 6.1e-43 146.3 7.7 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1765) Aim21 PF11489.8 KKK22313.1 - 2.3e-255 850.0 71.9 1e-254 847.9 71.9 1.9 1 1 0 1 1 1 1 Altered inheritance of mitochondria protein 21 TFIIB PF00382.19 KKK22314.1 - 6.8e-39 131.8 0.2 5e-19 68.1 0.1 2.4 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 KKK22314.1 - 3e-10 39.5 0.8 3e-10 39.5 0.8 1.7 2 0 0 2 2 2 1 TFIIB zinc-binding RB_B PF01857.20 KKK22314.1 - 0.0013 18.7 0.1 0.0035 17.4 0.1 1.7 2 0 0 2 2 2 1 Retinoblastoma-associated protein B domain Cyclin_N PF00134.23 KKK22314.1 - 0.012 15.4 0.3 2.4 7.9 0.1 2.4 2 0 0 2 2 2 0 Cyclin, N-terminal domain Cyclin_C PF02984.19 KKK22314.1 - 0.032 14.3 0.0 7.3 6.7 0.0 2.5 2 1 0 2 2 2 0 Cyclin, C-terminal domain Sigma70_r4 PF04545.16 KKK22314.1 - 0.066 12.7 0.0 0.36 10.4 0.0 2.1 2 0 0 2 2 2 0 Sigma-70, region 4 TMIE PF16038.5 KKK22314.1 - 1 9.3 5.5 0.49 10.3 0.6 2.5 2 0 0 2 2 2 0 TMIE protein zf-ribbon_3 PF13248.6 KKK22314.1 - 1.1 8.7 6.2 8.5 5.9 0.3 2.6 3 0 0 3 3 3 0 zinc-ribbon domain TPR_19 PF14559.6 KKK22315.1 - 1.2e-11 44.9 0.1 6.1e-05 23.5 0.1 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 KKK22315.1 - 0.00015 22.3 0.0 0.15 12.7 0.1 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 KKK22315.1 - 0.00018 21.4 0.1 0.35 11.1 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 KKK22315.1 - 0.00077 19.9 0.5 5.8 7.8 0.0 3.8 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_21 PF09976.9 KKK22315.1 - 0.0016 18.2 0.6 0.095 12.4 0.1 2.2 1 1 1 2 2 2 1 Tetratricopeptide repeat-like domain TPR_8 PF13181.6 KKK22315.1 - 0.0016 18.5 0.0 10 6.6 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat BTAD PF03704.17 KKK22315.1 - 0.0064 16.9 2.3 1.7 9.1 0.2 2.4 2 0 0 2 2 2 2 Bacterial transcriptional activator domain TPR_12 PF13424.6 KKK22315.1 - 0.019 15.3 0.3 0.019 15.3 0.3 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 KKK22315.1 - 0.091 12.4 0.8 5 6.8 0.1 2.5 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB1_HrpK) TPR_4 PF07721.14 KKK22315.1 - 0.12 13.1 0.1 58 4.7 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Coatomer_E PF04733.14 KKK22315.1 - 0.13 11.7 0.5 0.73 9.2 0.1 1.9 2 0 0 2 2 2 0 Coatomer epsilon subunit Cg6151-P PF10233.9 KKK22316.1 - 2.6e-45 153.4 15.6 3.1e-45 153.1 15.6 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P TMEM72 PF16054.5 KKK22316.1 - 0.00013 21.7 7.8 0.00018 21.3 7.8 1.2 1 0 0 1 1 1 1 Transmembrane protein family 72 COPI_assoc PF08507.10 KKK22316.1 - 0.0015 18.6 11.9 0.0023 18.0 11.9 1.4 1 0 0 1 1 1 1 COPI associated protein DHHC PF01529.20 KKK22316.1 - 0.76 9.9 7.4 1.1 9.3 7.4 1.3 1 0 0 1 1 1 0 DHHC palmitoyltransferase S_4TM PF18159.1 KKK22316.1 - 2.2 7.5 8.9 4.1 6.6 3.0 2.1 2 0 0 2 2 2 0 SMODS-associating 4TM effector domain YtpI PF14007.6 KKK22316.1 - 3 8.0 16.2 3.5 7.8 5.7 2.8 1 1 2 3 3 3 0 YtpI-like protein HlyIII PF03006.20 KKK22317.1 - 1.4e-64 217.9 9.5 1.7e-64 217.6 9.5 1.1 1 0 0 1 1 1 1 Haemolysin-III related Peptidase_U4 PF03419.13 KKK22317.1 - 0.076 12.3 5.9 0.027 13.8 3.1 1.7 1 1 1 2 2 2 0 Sporulation factor SpoIIGA CSN8_PSD8_EIF3K PF10075.9 KKK22318.1 - 0.00031 20.8 0.1 0.00058 19.9 0.1 1.4 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family SAC3_GANP PF03399.16 KKK22318.1 - 0.037 13.4 0.0 0.053 12.9 0.0 1.2 1 0 0 1 1 1 0 SAC3/GANP family Pkinase PF00069.25 KKK22319.1 - 1.9e-53 181.5 0.0 2.4e-53 181.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK22319.1 - 1.4e-32 113.0 0.0 1.7e-32 112.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KKK22319.1 - 0.0021 18.0 0.0 0.0071 16.3 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KKK22319.1 - 0.0051 16.2 0.0 0.011 15.1 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 KKK22319.1 - 0.0085 15.5 0.0 0.012 14.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KKK22319.1 - 0.067 12.1 0.0 0.097 11.6 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Choline_kinase PF01633.20 KKK22319.1 - 0.18 11.4 0.0 0.33 10.5 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase TFR_dimer PF04253.15 KKK22321.1 - 3.9e-37 127.0 0.1 7.6e-37 126.1 0.1 1.5 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 KKK22321.1 - 3.2e-16 59.6 0.0 8e-16 58.3 0.0 1.7 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 KKK22321.1 - 8.4e-15 54.6 0.0 1.5e-14 53.8 0.0 1.4 1 0 0 1 1 1 1 PA domain PKI PF02827.16 KKK22321.1 - 0.1 12.9 0.4 0.23 11.7 0.4 1.5 1 0 0 1 1 1 0 cAMP-dependent protein kinase inhibitor Sec1 PF00995.23 KKK22322.1 - 2e-114 384.0 0.0 2.2e-114 383.8 0.0 1.0 1 0 0 1 1 1 1 Sec1 family DUF1481 PF07356.12 KKK22323.1 - 0.027 14.3 1.1 0.027 14.3 1.1 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF1481) SF3b1 PF08920.10 KKK22324.1 - 1.8e-34 118.8 13.7 2e-33 115.4 9.4 3.2 1 1 1 2 2 2 1 Splicing factor 3B subunit 1 HEAT_2 PF13646.6 KKK22324.1 - 1.5e-11 44.5 8.2 0.22 12.0 0.1 8.8 7 1 3 10 10 10 3 HEAT repeats HEAT_EZ PF13513.6 KKK22324.1 - 4e-10 40.0 5.4 0.012 16.1 0.0 7.0 6 1 1 7 7 6 2 HEAT-like repeat HEAT PF02985.22 KKK22324.1 - 4.2e-09 35.9 9.7 0.031 14.5 0.5 8.7 9 0 0 9 9 9 2 HEAT repeat Vac14_Fab1_bd PF12755.7 KKK22324.1 - 2.6e-05 24.7 0.3 1.7 9.3 0.0 5.1 4 1 1 5 5 5 1 Vacuolar 14 Fab1-binding region UNC45-central PF11701.8 KKK22324.1 - 9.7e-05 22.4 0.0 0.00038 20.5 0.0 1.9 2 0 0 2 2 2 1 Myosin-binding striated muscle assembly central DUF3385 PF11865.8 KKK22324.1 - 0.00017 21.5 1.9 0.26 11.2 0.0 5.1 4 1 1 5 5 5 1 Domain of unknown function (DUF3385) Adaptin_N PF01602.20 KKK22324.1 - 0.00018 20.2 0.5 0.17 10.4 0.2 3.5 2 2 1 3 3 3 1 Adaptin N terminal region NUC173 PF08161.12 KKK22324.1 - 0.00022 21.0 0.1 1.2 8.7 0.0 3.9 5 0 0 5 5 5 2 NUC173 domain Cnd1 PF12717.7 KKK22324.1 - 0.00045 20.3 5.5 0.39 10.8 0.1 5.6 4 2 2 6 6 6 1 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 KKK22324.1 - 0.0018 17.9 0.1 0.96 9.0 0.0 3.3 3 0 0 3 3 3 1 CLASP N terminal MMS19_C PF12460.8 KKK22324.1 - 0.0078 15.4 0.0 0.3 10.2 0.0 2.8 2 1 0 2 2 2 1 RNAPII transcription regulator C-terminal IFRD PF05004.13 KKK22324.1 - 0.01 15.0 0.0 0.29 10.2 0.0 2.6 2 0 0 2 2 2 0 Interferon-related developmental regulator (IFRD) TAF6_C PF07571.13 KKK22324.1 - 0.058 13.7 0.0 1 9.7 0.0 2.9 2 0 0 2 2 2 0 TAF6 C-terminal HEAT repeat domain DRIM PF07539.12 KKK22324.1 - 0.12 10.7 0.2 6.8 4.9 0.0 3.5 2 1 2 4 4 4 0 Down-regulated in metastasis EF-1_beta_acid PF10587.9 KKK22324.1 - 0.92 10.0 3.1 5.2 7.6 3.1 2.4 1 0 0 1 1 1 0 Eukaryotic elongation factor 1 beta central acidic region RR_TM4-6 PF06459.12 KKK22324.1 - 2.2 8.0 4.4 4.5 7.0 4.3 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 UQ_con PF00179.26 KKK22325.1 - 8.1e-28 96.8 0.0 9.6e-28 96.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KKK22325.1 - 5.2e-06 26.2 0.0 6.7e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 KKK22325.1 - 0.0087 16.3 0.4 0.025 14.8 0.4 1.7 1 1 1 2 2 2 1 RWD domain Pkinase PF00069.25 KKK22326.1 - 1.5e-59 201.5 0.0 2e-59 201.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK22326.1 - 4.1e-27 95.1 0.0 5.8e-27 94.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KKK22326.1 - 9.8e-05 21.8 0.0 0.00014 21.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KKK22326.1 - 0.0019 17.6 0.1 0.0047 16.3 0.1 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KKK22326.1 - 0.0033 16.2 0.1 0.0087 14.9 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase Lipase_3 PF01764.25 KKK22327.1 - 7.6e-19 68.0 0.0 1.2e-18 67.3 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) DUF676 PF05057.14 KKK22327.1 - 0.04 13.4 0.0 0.054 13.0 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 KKK22327.1 - 0.12 13.0 0.1 0.17 12.4 0.1 1.3 1 1 0 1 1 1 0 Alpha/beta hydrolase family Herpes_BBRF1 PF04793.12 KKK22327.1 - 0.17 10.9 0.0 0.26 10.3 0.0 1.2 1 0 0 1 1 1 0 BRRF1-like protein PGAP1 PF07819.13 KKK22327.1 - 0.18 11.5 0.0 0.3 10.8 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Telomere_reg-2 PF10193.9 KKK22329.1 - 9.4e-32 109.7 0.0 2.7e-31 108.2 0.0 1.9 1 0 0 1 1 1 1 Telomere length regulation protein TFIIA PF03153.13 KKK22329.1 - 0.15 12.0 3.0 0.37 10.7 3.0 1.6 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TLP-20 PF06088.11 KKK22329.1 - 0.19 11.6 1.4 5.9 6.8 0.0 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) ThiF PF00899.21 KKK22330.1 - 1.4e-47 162.1 0.0 1.1e-35 123.2 0.0 2.1 1 1 1 2 2 2 2 ThiF family E2_bind PF08825.10 KKK22330.1 - 4.7e-30 103.6 0.1 7.1e-30 103.0 0.1 1.3 1 0 0 1 1 1 1 E2 binding domain Shikimate_DH PF01488.20 KKK22330.1 - 0.00058 19.9 0.1 0.003 17.6 0.0 2.0 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase E1_UFD PF09358.10 KKK22330.1 - 0.049 14.3 0.0 0.15 12.8 0.0 1.8 1 0 0 1 1 1 0 Ubiquitin fold domain PglD_N PF17836.1 KKK22330.1 - 0.17 12.6 0.1 1.6 9.4 0.7 2.5 2 1 0 2 2 2 0 PglD N-terminal domain UBA_e1_thiolCys PF10585.9 KKK22330.1 - 1.4 8.8 3.5 19 5.1 0.1 2.2 1 1 1 2 2 2 0 Ubiquitin-activating enzyme active site RNA_pol_A_bac PF01000.26 KKK22331.1 - 1e-26 93.5 0.0 1.8e-26 92.7 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 KKK22331.1 - 9.5e-18 63.4 0.0 1.4e-17 62.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Complex1_49kDa PF00346.19 KKK22332.1 - 8.5e-123 408.7 0.0 1.3e-122 408.2 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases PF00374.19 KKK22332.1 - 0.0012 17.8 0.0 0.0018 17.3 0.0 1.3 1 0 0 1 1 1 1 Nickel-dependent hydrogenase IF-2B PF01008.17 KKK22333.1 - 3.2e-20 72.5 0.0 7.2e-20 71.4 0.0 1.6 1 1 0 1 1 1 1 Initiation factor 2 subunit family NUDIX PF00293.28 KKK22333.1 - 1.3e-05 25.2 0.0 3.1e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 NUDIX domain adh_short_C2 PF13561.6 KKK22335.1 - 3.3e-40 138.1 0.0 3.9e-40 137.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KKK22335.1 - 1.7e-28 99.4 0.0 2.1e-28 99.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KKK22335.1 - 2.9e-06 27.3 0.0 4.7e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 KR domain Dak1_2 PF13684.6 KKK22335.1 - 0.084 11.9 0.0 0.18 10.9 0.0 1.5 1 0 0 1 1 1 0 Dihydroxyacetone kinase family ThiF PF00899.21 KKK22335.1 - 0.13 11.5 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 ThiF family Fungal_trans_2 PF11951.8 KKK22336.1 - 2.2e-06 26.8 0.1 3e-06 26.3 0.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Catalase PF00199.19 KKK22337.1 - 7.6e-194 644.1 0.4 9.2e-194 643.8 0.4 1.0 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 KKK22337.1 - 2.6e-11 43.5 0.0 8.6e-11 41.9 0.0 1.9 1 0 0 1 1 1 1 Catalase-related immune-responsive Sugar_tr PF00083.24 KKK22338.1 - 2e-87 294.0 21.2 2.4e-87 293.7 21.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKK22338.1 - 8.3e-15 54.6 35.7 1.1e-10 41.0 27.8 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KKK22338.1 - 0.00089 18.2 3.9 0.00089 18.2 3.9 2.3 2 0 0 2 2 2 2 MFS_1 like family ECH_1 PF00378.20 KKK22339.1 - 2.6e-78 262.8 0.1 3.1e-78 262.6 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KKK22339.1 - 3.2e-36 125.5 0.4 3.8e-33 115.4 0.1 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Rer1 PF03248.13 KKK22340.1 - 3.6e-80 267.7 6.1 4.1e-80 267.5 6.1 1.0 1 0 0 1 1 1 1 Rer1 family LtrA PF06772.11 KKK22341.1 - 2.4e-37 129.0 22.6 3e-37 128.7 22.6 1.1 1 0 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) MFS_MOT1 PF16983.5 KKK22341.1 - 7.7 7.0 8.4 1.3 9.4 3.6 2.3 2 1 0 2 2 2 0 Molybdate transporter of MFS superfamily Lipase_3 PF01764.25 KKK22348.1 - 2.7e-06 27.3 0.0 7e-06 26.0 0.0 1.7 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 KKK22348.1 - 0.045 14.4 0.0 0.088 13.4 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family PGAP1 PF07819.13 KKK22348.1 - 0.051 13.3 0.0 0.078 12.7 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Hydrolase_4 PF12146.8 KKK22348.1 - 0.093 12.0 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Nucleoporin_FG PF13634.6 KKK22348.1 - 9 7.2 13.5 1.9 9.4 8.5 2.4 2 1 1 3 3 3 0 Nucleoporin FG repeat region VPS9 PF02204.18 KKK22349.1 - 4e-26 91.3 0.0 9.5e-26 90.0 0.0 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF5601 PF18151.1 KKK22349.1 - 0.19 12.1 0.1 0.73 10.2 0.1 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF5601) Pkinase PF00069.25 KKK22350.1 - 6.6e-11 42.1 0.0 3.1e-09 36.6 0.1 2.7 2 1 0 2 2 2 1 Protein kinase domain Kinase-like PF14531.6 KKK22350.1 - 0.0003 20.2 0.2 0.19 11.0 0.1 2.7 3 0 0 3 3 3 2 Kinase-like Pkinase_Tyr PF07714.17 KKK22350.1 - 0.0012 18.2 0.1 0.07 12.4 0.2 2.8 2 1 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 KKK22350.1 - 0.0075 16.2 0.0 0.013 15.4 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KKK22350.1 - 0.17 11.2 0.0 0.31 10.4 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Rieske PF00355.26 KKK22351.1 - 4.5e-09 36.1 0.0 9.4e-09 35.1 0.0 1.5 1 1 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 KKK22351.1 - 5.2e-05 23.1 0.0 9.1e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Ran_BP1 PF00638.18 KKK22352.1 - 2.9e-19 69.5 0.1 5.4e-19 68.6 0.1 1.3 1 0 0 1 1 1 1 RanBP1 domain DEAD PF00270.29 KKK22353.1 - 9.8e-27 93.8 0.0 1.8e-26 92.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF1998 PF09369.10 KKK22353.1 - 6e-18 65.4 0.9 2.4e-17 63.5 0.9 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF1998) Helicase_C PF00271.31 KKK22353.1 - 3.1e-12 46.8 0.1 1.5e-11 44.6 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KKK22353.1 - 5e-05 23.4 0.0 0.0001 22.4 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CDT1 PF08839.11 KKK22353.1 - 0.00011 22.5 0.0 0.00029 21.2 0.0 1.7 1 0 0 1 1 1 1 DNA replication factor CDT1 like TFIIF_alpha PF05793.12 KKK22353.1 - 0.16 10.5 4.9 0.25 9.9 4.9 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Fungal_trans_2 PF11951.8 KKK22354.1 - 3.4e-13 49.2 0.7 4.8e-13 48.7 0.7 1.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK22354.1 - 1.3e-07 31.6 8.6 2.2e-07 30.8 8.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Formyl_trans_N PF00551.19 KKK22355.1 - 8.3e-37 126.7 0.0 9.7e-37 126.4 0.0 1.1 1 0 0 1 1 1 1 Formyl transferase PPR_2 PF13041.6 KKK22356.1 - 1.7e-24 85.7 2.2 1.4e-17 63.6 0.7 3.1 3 0 0 3 3 3 2 PPR repeat family PPR_3 PF13812.6 KKK22356.1 - 1.2e-10 41.3 0.2 9e-06 25.7 0.1 2.9 3 0 0 3 3 3 2 Pentatricopeptide repeat domain PPR PF01535.20 KKK22356.1 - 1.7e-07 31.0 0.2 0.13 12.5 0.2 4.2 3 0 0 3 3 3 2 PPR repeat PPR_long PF17177.4 KKK22356.1 - 1.1e-05 24.9 0.0 3.1e-05 23.4 0.0 1.7 2 0 0 2 2 2 1 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 KKK22356.1 - 0.00022 20.8 0.1 0.15 11.7 0.0 3.3 3 0 0 3 3 3 2 PPR repeat Yip1 PF04893.17 KKK22357.1 - 3.4e-14 52.9 13.3 5.5e-14 52.3 13.3 1.4 1 0 0 1 1 1 1 Yip1 domain DUF1282 PF06930.12 KKK22357.1 - 0.07 12.9 5.5 0.11 12.3 5.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1282) zf-RING_2 PF13639.6 KKK22358.1 - 2.2e-12 47.1 5.2 3.4e-12 46.5 5.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 KKK22358.1 - 5.5e-09 36.2 3.0 1.1e-08 35.2 3.0 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 KKK22358.1 - 5.3e-08 32.6 4.4 8.8e-08 31.9 4.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KKK22358.1 - 5.9e-08 32.5 4.4 9e-08 31.9 4.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KKK22358.1 - 2.6e-07 30.2 1.5 4.8e-07 29.4 1.5 1.4 1 0 0 1 1 1 1 RING-like zinc finger Zn_ribbon_17 PF17120.5 KKK22358.1 - 2e-05 24.1 1.5 3.2e-05 23.5 1.5 1.2 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 KKK22358.1 - 9.1e-05 22.3 3.0 0.00014 21.8 3.0 1.3 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KKK22358.1 - 0.00018 21.3 2.2 0.00032 20.5 2.2 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 KKK22358.1 - 0.00053 20.0 2.1 0.0012 18.9 2.1 1.6 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 KKK22358.1 - 0.00069 19.6 4.2 0.0013 18.7 4.2 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KKK22358.1 - 0.0015 18.3 3.1 0.0024 17.7 3.1 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.7 KKK22358.1 - 0.0027 17.8 5.5 0.0041 17.2 5.5 1.3 1 0 0 1 1 1 1 RING-variant domain zf-C3H2C3 PF17122.5 KKK22358.1 - 0.0045 17.0 1.7 0.0089 16.0 1.7 1.4 1 0 0 1 1 1 1 Zinc-finger zf-Nse PF11789.8 KKK22358.1 - 0.023 14.5 2.0 0.049 13.5 1.4 1.8 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_5 PF17121.5 KKK22358.1 - 0.11 12.4 1.3 0.2 11.6 1.3 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 KKK22358.1 - 0.27 11.1 3.7 0.43 10.4 3.7 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.8 KKK22358.1 - 0.32 11.2 3.3 0.6 10.3 3.3 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain zf-RING-like PF08746.11 KKK22358.1 - 0.43 10.9 2.6 0.75 10.1 2.6 1.3 1 0 0 1 1 1 0 RING-like domain PHD PF00628.29 KKK22358.1 - 0.58 10.1 3.9 0.96 9.4 3.9 1.4 1 0 0 1 1 1 0 PHD-finger ECM11 PF15463.6 KKK22359.1 - 8.9e-37 126.6 2.0 8.9e-37 126.6 2.0 3.0 3 0 0 3 3 3 1 Extracellular mutant protein 11 RNA_pol_I_TF PF04090.12 KKK22359.1 - 4.6e-12 45.8 0.0 3.1e-11 43.1 0.0 2.0 1 1 0 1 1 1 1 RNA polymerase I specific initiation factor NifU_N PF01592.16 KKK22361.1 - 2.2e-50 170.1 0.0 2.8e-50 169.8 0.0 1.1 1 0 0 1 1 1 1 NifU-like N terminal domain His_Phos_1 PF00300.22 KKK22363.1 - 1.2e-10 41.4 0.1 4e-10 39.7 0.1 1.7 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Ribosomal_L22 PF00237.19 KKK22364.1 - 3.3e-31 107.6 1.1 5.4e-31 106.9 0.1 1.9 2 0 0 2 2 2 1 Ribosomal protein L22p/L17e RRM_1 PF00076.22 KKK22365.1 - 2.2e-30 104.3 0.0 1.8e-11 43.7 0.0 4.3 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KKK22365.1 - 3.7e-06 26.8 0.1 0.15 12.1 0.0 2.6 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 KKK22365.1 - 0.017 15.0 0.0 1.4 8.8 0.1 2.4 2 0 0 2 2 2 0 Occluded RNA-recognition motif AMP-binding PF00501.28 KKK22366.1 - 1.3e-94 317.3 0.0 1.5e-94 317.0 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KKK22366.1 - 3.2e-16 60.1 0.0 8.2e-16 58.8 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain SET PF00856.28 KKK22367.1 - 3.8e-11 43.7 0.2 2.8e-09 37.6 0.1 2.7 2 1 0 2 2 2 1 SET domain DUF2052 PF09747.9 KKK22368.1 - 1.2e-22 81.0 16.9 9.5e-12 45.5 0.6 2.2 1 1 1 2 2 2 2 Coiled-coil domain containing protein (DUF2052) Spermine_synth PF01564.17 KKK22369.1 - 4.4e-07 29.5 0.0 7.2e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Methyltransf_30 PF05430.11 KKK22369.1 - 0.018 14.9 0.0 0.035 14.0 0.0 1.4 1 0 0 1 1 1 0 S-adenosyl-L-methionine-dependent methyltransferase SCIMP PF15050.6 KKK22399.1 - 0.019 15.4 4.3 0.43 11.1 0.0 3.2 3 0 0 3 3 3 0 SCIMP protein UPF0242 PF06785.11 KKK22399.1 - 0.24 11.5 0.1 0.24 11.5 0.1 2.1 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus Oxidored_q3 PF00499.20 KKK22399.1 - 4.2 7.1 19.5 0.18 11.5 7.4 3.1 1 1 1 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 Sec61_beta PF03911.16 KKK22400.1 - 7.4e-18 64.3 1.0 1e-17 63.8 1.0 1.2 1 0 0 1 1 1 1 Sec61beta family SSF PF00474.17 KKK22401.1 - 7.4e-13 48.1 33.1 1.1e-10 41.0 17.4 2.5 3 0 0 3 3 3 2 Sodium:solute symporter family Gram_pos_anchor PF00746.21 KKK22433.1 - 0.51 10.3 2.4 0.68 9.9 1.3 1.7 2 0 0 2 2 2 0 LPXTG cell wall anchor motif OTU PF02338.19 KKK22434.1 - 4.9e-21 75.5 0.2 7.4e-20 71.7 0.2 2.4 1 1 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 KKK22434.1 - 2.6e-07 30.3 0.1 2.1e-05 24.1 0.0 2.7 3 0 0 3 3 3 2 Peptidase C65 Otubain Cep57_MT_bd PF06657.13 KKK22434.1 - 0.26 11.8 5.2 0.67 10.5 5.2 1.7 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 FUSC PF04632.12 KKK22434.1 - 4.2 5.8 5.3 5.6 5.4 5.3 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family adh_short_C2 PF13561.6 KKK22435.1 - 2.1e-48 164.9 0.0 2.5e-48 164.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KKK22435.1 - 2.6e-44 151.0 0.0 3.4e-44 150.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KKK22435.1 - 6e-07 29.6 0.0 1e-06 28.8 0.0 1.3 1 0 0 1 1 1 1 KR domain Trehalase PF01204.18 KKK22436.1 - 1.1e-197 658.0 0.0 1.2e-197 657.8 0.0 1.0 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.11 KKK22436.1 - 2.3e-07 30.4 0.1 3.9e-07 29.7 0.1 1.4 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain ICL PF00463.21 KKK22437.1 - 0 1009.3 4.7 0 1009.1 4.7 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 KKK22437.1 - 1.3e-11 44.4 0.3 3.3e-11 43.1 0.1 1.7 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase DUF3197 PF11432.8 KKK22437.1 - 0.014 15.3 0.5 6.9 6.6 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3197) Aldedh PF00171.22 KKK22438.1 - 2.8e-63 214.1 0.0 1.1e-61 208.7 0.0 2.0 2 0 0 2 2 2 2 Aldehyde dehydrogenase family Amidase PF01425.21 KKK22454.1 - 6.1e-103 345.2 0.0 1e-102 344.5 0.0 1.3 1 1 0 1 1 1 1 Amidase Thioesterase PF00975.20 KKK22454.1 - 0.09 12.9 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Rep_fac_C PF08542.11 KKK22455.1 - 2.3e-22 79.2 0.0 5.7e-22 77.9 0.0 1.7 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 KKK22455.1 - 2.6e-13 50.1 0.0 6.1e-10 39.1 0.0 2.2 1 1 1 2 2 2 2 DNA polymerase III, delta subunit AAA PF00004.29 KKK22455.1 - 1.4e-11 45.0 0.0 2.2e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 KKK22455.1 - 5.9e-07 29.6 0.0 2.2e-06 27.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KKK22455.1 - 6.2e-06 26.7 0.0 0.00072 20.0 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain Viral_helicase1 PF01443.18 KKK22455.1 - 1.1e-05 25.3 0.0 1.8e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 KKK22455.1 - 5.5e-05 23.4 0.0 0.055 13.8 0.0 2.6 2 1 1 3 3 2 2 AAA domain RuvB_N PF05496.12 KKK22455.1 - 0.00014 21.6 0.0 0.00032 20.5 0.0 1.6 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain DNA_pol3_delta PF06144.13 KKK22455.1 - 0.00039 20.2 0.0 0.00057 19.7 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_3 PF07726.11 KKK22455.1 - 0.00045 20.1 0.0 0.00084 19.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 KKK22455.1 - 0.0016 17.8 0.0 0.019 14.3 0.0 2.1 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI Rad17 PF03215.15 KKK22455.1 - 0.0019 18.1 0.0 0.0036 17.2 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_assoc_2 PF16193.5 KKK22455.1 - 0.0054 17.0 0.0 0.014 15.7 0.0 1.8 1 0 0 1 1 1 1 AAA C-terminal domain MeaB PF03308.16 KKK22455.1 - 0.01 14.8 0.0 0.018 14.0 0.0 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_11 PF13086.6 KKK22455.1 - 0.011 15.5 0.0 0.02 14.7 0.0 1.3 1 1 0 1 1 1 0 AAA domain DUF5119 PF17145.4 KKK22455.1 - 0.014 15.4 0.0 1.7 8.6 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5119) AAA_24 PF13479.6 KKK22455.1 - 0.018 14.7 0.0 0.11 12.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain TniB PF05621.11 KKK22455.1 - 0.018 14.4 0.0 3.4 7.0 0.0 2.4 2 0 0 2 2 2 0 Bacterial TniB protein AAA_19 PF13245.6 KKK22455.1 - 0.032 14.6 0.1 0.14 12.5 0.1 1.9 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 KKK22455.1 - 0.036 14.0 0.2 0.16 11.9 0.1 2.1 1 1 1 2 2 2 0 NTPase DEAD PF00270.29 KKK22455.1 - 0.087 12.6 0.1 1.1 9.0 0.0 2.4 1 1 1 2 2 2 0 DEAD/DEAH box helicase Porin_3 PF01459.22 KKK22457.1 - 5.7e-85 285.1 0.2 6.6e-85 284.8 0.2 1.0 1 0 0 1 1 1 1 Eukaryotic porin Zds_C PF08632.10 KKK22457.1 - 0.0088 15.8 0.0 0.018 14.8 0.0 1.5 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term 6PF2K PF01591.18 KKK22458.1 - 1.4e-51 174.9 0.0 2.3e-51 174.3 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 KKK22458.1 - 5.4e-20 71.9 0.2 2.4e-19 69.8 0.2 1.9 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 KKK22458.1 - 0.0016 18.6 0.0 0.0082 16.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 KKK22459.1 - 3.6e-11 43.7 0.3 8e-10 39.4 0.1 2.8 2 1 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 KKK22459.1 - 3e-07 30.5 1.0 0.0013 18.6 0.1 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system IPPT PF01715.17 KKK22460.1 - 8.2e-54 182.8 0.1 1.4e-53 182.0 0.1 1.3 1 0 0 1 1 1 1 IPP transferase zf-met PF12874.7 KKK22460.1 - 1e-06 28.9 0.7 1.8e-06 28.1 0.7 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KKK22460.1 - 1.4e-06 28.4 1.0 2.6e-06 27.6 1.0 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding AAA_33 PF13671.6 KKK22460.1 - 6.2e-05 23.2 0.4 0.01 16.0 0.0 3.4 3 1 0 3 3 3 1 AAA domain AAA_16 PF13191.6 KKK22460.1 - 0.00079 19.8 0.1 0.012 16.0 0.0 2.6 2 2 0 2 2 2 1 AAA ATPase domain IPT PF01745.16 KKK22460.1 - 0.0017 17.8 0.0 0.0043 16.5 0.0 1.7 1 0 0 1 1 1 1 Isopentenyl transferase AAA_25 PF13481.6 KKK22460.1 - 0.003 17.2 0.0 0.013 15.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KKK22460.1 - 0.0049 17.4 0.1 0.16 12.5 0.0 3.0 2 1 2 4 4 4 1 AAA domain FAM193_C PF15914.5 KKK22460.1 - 0.0052 16.5 0.2 0.45 10.3 0.0 2.6 2 0 0 2 2 2 1 FAM193 family C-terminal Cytidylate_kin PF02224.18 KKK22460.1 - 0.017 14.9 0.0 0.064 13.0 0.0 2.0 2 0 0 2 2 2 0 Cytidylate kinase AAA_22 PF13401.6 KKK22460.1 - 0.043 14.1 0.0 0.11 12.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.17 KKK22460.1 - 0.05 13.7 0.3 0.89 9.6 0.1 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain Ploopntkinase3 PF18751.1 KKK22460.1 - 0.062 13.2 0.1 1 9.2 0.0 2.5 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 zf-C2H2_2 PF12756.7 KKK22460.1 - 0.064 13.6 0.7 0.12 12.7 0.7 1.4 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) AKAP95 PF04988.12 KKK22460.1 - 0.13 12.5 0.6 0.29 11.3 0.2 1.8 2 0 0 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) ABC_tran PF00005.27 KKK22460.1 - 0.27 11.8 2.0 0.45 11.0 0.3 2.6 2 1 0 2 2 1 0 ABC transporter AAA_28 PF13521.6 KKK22460.1 - 0.43 10.8 0.0 0.43 10.8 0.0 2.7 4 1 0 4 4 4 0 AAA domain Urm1 PF09138.11 KKK22461.1 - 8e-36 122.3 0.1 9.5e-36 122.1 0.1 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.20 KKK22461.1 - 0.00084 19.9 0.0 0.0011 19.5 0.0 1.3 1 0 0 1 1 1 1 ThiS family WD40 PF00400.32 KKK22462.1 - 4.3e-29 100.1 15.7 0.0021 18.9 0.0 12.2 13 0 0 13 13 13 8 WD domain, G-beta repeat Ge1_WD40 PF16529.5 KKK22462.1 - 0.029 13.4 0.8 1.5 7.7 0.0 3.4 3 1 2 5 5 5 0 WD40 region of Ge1, enhancer of mRNA-decapping protein RAI1 PF08652.11 KKK22463.1 - 5e-30 103.5 0.0 9.8e-30 102.6 0.0 1.5 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease DUF410 PF04190.13 KKK22464.1 - 3.4e-84 282.6 0.0 4.5e-84 282.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF410) MFS_1 PF07690.16 KKK22466.1 - 3.3e-16 59.1 29.6 3.3e-16 59.1 29.6 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Mon1 PF03164.14 KKK22467.1 - 3.1e-154 513.9 0.0 3.7e-154 513.7 0.0 1.0 1 0 0 1 1 1 1 Trafficking protein Mon1 zf-HIT PF04438.16 KKK22468.1 - 2.2e-09 37.0 12.2 3.6e-09 36.3 12.2 1.4 1 0 0 1 1 1 1 HIT zinc finger Phage_NinH PF06322.11 KKK22468.1 - 0.033 14.1 0.2 0.081 12.8 0.2 1.6 1 0 0 1 1 1 0 Phage NinH protein Ribosomal_60s PF00428.19 KKK22468.1 - 0.62 10.7 14.8 4 8.1 8.5 2.4 1 1 1 2 2 2 0 60s Acidic ribosomal protein RR_TM4-6 PF06459.12 KKK22468.1 - 0.93 9.3 6.0 1.2 8.9 6.0 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF3602 PF12223.8 KKK22468.1 - 1.8 9.2 5.1 1.3 9.7 2.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3602) Dopey_N PF04118.14 KKK22469.1 - 3.2e-110 368.0 0.0 1.5e-109 365.8 0.0 2.2 2 0 0 2 2 2 1 Dopey, N-terminal DUF3052 PF11253.8 KKK22469.1 - 0.06 13.3 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3052) MazG PF03819.17 KKK22469.1 - 0.17 12.1 0.0 0.45 10.7 0.0 1.7 1 0 0 1 1 1 0 MazG nucleotide pyrophosphohydrolase domain CAP_N PF01213.19 KKK22469.1 - 6.8 6.1 4.8 16 4.9 4.8 1.5 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Glyco_hydro_28 PF00295.17 KKK22506.1 - 1.9e-47 162.0 6.5 5.8e-46 157.0 6.5 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 28 adh_short PF00106.25 KKK22507.1 - 4e-37 127.6 0.3 1.1e-36 126.1 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KKK22507.1 - 1.4e-24 87.0 0.0 1.9e-24 86.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KKK22507.1 - 9.3e-07 28.9 0.4 0.0026 17.7 0.1 2.2 2 0 0 2 2 2 2 KR domain Epimerase PF01370.21 KKK22507.1 - 0.00041 19.9 0.0 0.00089 18.8 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family UPF0181 PF03701.14 KKK22507.1 - 0.033 13.8 0.1 0.08 12.6 0.1 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0181) UPF0146 PF03686.13 KKK22507.1 - 0.16 11.8 0.0 0.34 10.8 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0146) ABC2_membrane PF01061.24 KKK22508.1 - 8.8e-70 234.4 54.7 5.1e-38 130.6 26.6 2.7 3 0 0 3 3 2 2 ABC-2 type transporter ABC_tran PF00005.27 KKK22508.1 - 1.8e-36 125.6 0.0 1.9e-17 64.1 0.0 2.8 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 KKK22508.1 - 2.8e-24 84.8 0.2 2.8e-24 84.8 0.2 2.5 2 0 0 2 2 1 1 CDR ABC transporter Fungal_trans PF04082.18 KKK22508.1 - 1.1e-18 67.2 0.2 2.2e-18 66.2 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain ABC2_membrane_3 PF12698.7 KKK22508.1 - 1.1e-07 31.3 41.6 0.00015 21.0 13.5 2.4 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_16 PF13191.6 KKK22508.1 - 1.1e-06 29.2 0.1 0.00018 21.9 0.1 2.8 2 0 0 2 2 2 1 AAA ATPase domain Zn_clus PF00172.18 KKK22508.1 - 1.3e-06 28.4 7.1 2.5e-06 27.5 7.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RsgA_GTPase PF03193.16 KKK22508.1 - 5.7e-05 23.1 0.1 0.0029 17.5 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 KKK22508.1 - 0.0002 21.1 0.6 0.015 15.1 0.3 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_21 PF13304.6 KKK22508.1 - 0.00021 21.2 2.7 0.32 10.8 0.1 2.9 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 KKK22508.1 - 0.00048 19.8 2.6 0.16 11.6 0.1 3.7 4 0 0 4 4 4 1 AAA domain MMR_HSR1 PF01926.23 KKK22508.1 - 0.00052 20.1 0.1 0.094 12.8 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.6 KKK22508.1 - 0.0068 16.7 0.1 0.36 11.1 0.0 3.0 3 0 0 3 3 2 1 AAA domain ABC_trans_N PF14510.6 KKK22508.1 - 0.012 16.2 1.1 0.037 14.6 0.0 2.5 2 0 0 2 2 1 0 ABC-transporter N-terminal AAA_30 PF13604.6 KKK22508.1 - 0.03 14.1 0.6 1.7 8.3 0.2 2.5 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.19 KKK22508.1 - 0.042 13.3 0.0 4.6 6.6 0.0 2.4 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_18 PF13238.6 KKK22508.1 - 0.044 14.3 0.0 0.46 11.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KKK22508.1 - 0.064 13.4 0.1 1.3 9.2 0.1 2.6 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 KKK22508.1 - 0.15 12.6 1.7 0.3 11.5 0.3 2.2 2 0 0 2 2 2 0 AAA domain Pox_A_type_inc PF04508.12 KKK22508.1 - 0.18 11.7 1.4 0.56 10.1 1.4 1.9 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat AAA_28 PF13521.6 KKK22508.1 - 0.19 12.0 1.1 0.53 10.5 0.8 2.0 2 0 0 2 2 1 0 AAA domain ABC2_membrane_2 PF12679.7 KKK22508.1 - 3.1 7.0 27.3 0.75 9.0 9.1 2.5 2 0 0 2 2 2 0 ABC-2 family transporter protein DUF1752 PF08550.10 KKK22509.1 - 1.2e-10 41.0 4.1 2.3e-10 40.1 4.1 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) SUI1 PF01253.22 KKK22510.1 - 1.6e-22 79.8 1.8 3.2e-22 78.8 1.8 1.5 1 0 0 1 1 1 1 Translation initiation factor SUI1 RcbX PF02341.15 KKK22510.1 - 0.068 13.4 0.0 0.15 12.3 0.0 1.6 1 1 0 1 1 1 0 RbcX protein Mannosyl_trans3 PF11051.8 KKK22511.1 - 0.022 14.1 0.0 0.035 13.5 0.0 1.2 1 0 0 1 1 1 0 Mannosyltransferase putative Glyco_transf_8 PF01501.20 KKK22511.1 - 0.19 11.2 3.2 1.1 8.8 0.6 2.6 2 1 0 2 2 2 0 Glycosyl transferase family 8 DHquinase_I PF01487.15 KKK22512.1 - 7.5e-29 101.6 0.0 1.1e-28 101.0 0.0 1.2 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.22 KKK22512.1 - 1.9e-18 67.1 0.1 5.4e-18 65.6 0.0 1.8 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.11 KKK22512.1 - 7.3e-13 48.6 0.0 2.8e-12 46.7 0.0 2.0 2 0 0 2 2 2 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.20 KKK22512.1 - 2e-08 34.4 0.1 1.5e-07 31.6 0.1 2.1 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase SDH_C PF18317.1 KKK22512.1 - 0.00013 21.7 0.0 0.00028 20.6 0.0 1.5 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain F420_oxidored PF03807.17 KKK22512.1 - 0.064 13.8 0.0 0.17 12.5 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent CDH-cyt PF16010.5 KKK22513.1 - 6e-21 74.9 1.4 1e-20 74.2 1.4 1.3 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase Cytochrom_B561 PF03188.16 KKK22513.1 - 3.6e-06 27.2 6.2 3.6e-06 27.2 6.2 2.2 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 DUF2427 PF10348.9 KKK22513.1 - 0.00033 20.4 1.2 0.00033 20.4 1.2 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF2427) DOMON PF03351.17 KKK22513.1 - 0.00068 19.9 0.0 0.0012 19.0 0.0 1.4 1 0 0 1 1 1 1 DOMON domain MIG-14_Wnt-bd PF06664.12 KKK22513.1 - 0.027 13.7 0.0 2.2 7.4 0.0 2.1 1 1 1 2 2 2 0 Wnt-binding factor required for Wnt secretion Ferric_reduct PF01794.19 KKK22513.1 - 1.4 9.0 6.6 1.2 9.3 2.7 2.6 2 1 0 2 2 2 0 Ferric reductase like transmembrane component Chromate_transp PF02417.15 KKK22514.1 - 5e-61 205.4 26.9 7.3e-35 120.4 12.5 2.4 2 0 0 2 2 2 2 Chromate transporter Spt5-NGN PF03439.13 KKK22514.1 - 0.22 11.4 0.0 0.42 10.5 0.0 1.4 1 0 0 1 1 1 0 Early transcription elongation factor of RNA pol II, NGN section F-box-like PF12937.7 KKK22515.1 - 8.5e-06 25.6 0.4 8.5e-06 25.6 0.4 2.7 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 KKK22515.1 - 0.013 15.4 0.5 0.042 13.7 0.5 1.9 1 0 0 1 1 1 0 F-box domain Fungal_trans PF04082.18 KKK22516.1 - 6.7e-18 64.7 0.0 1.3e-17 63.7 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK22516.1 - 9e-08 32.1 13.8 1.6e-07 31.3 13.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fringe PF02434.16 KKK22517.1 - 2.4e-09 37.0 0.2 2.4e-06 27.2 0.0 3.8 3 1 0 3 3 3 1 Fringe-like PAN_1 PF00024.26 KKK22517.1 - 0.0057 16.6 0.3 0.011 15.7 0.3 1.4 1 0 0 1 1 1 1 PAN domain Mito_carr PF00153.27 KKK22518.1 - 1.2e-66 220.6 0.2 4.7e-22 77.7 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KKK22518.1 - 0.057 12.6 0.1 7.9 5.5 0.0 3.1 3 1 0 3 3 3 0 Gammaproteobacterial serine protease Cgr1 PF03879.14 KKK22519.1 - 1.6e-33 115.3 29.2 1.8e-33 115.2 29.2 1.0 1 0 0 1 1 1 1 Cgr1 family RRT14 PF17075.5 KKK22519.1 - 0.26 11.4 15.8 0.35 11.0 15.8 1.1 1 0 0 1 1 1 0 Regular of rDNA transcription protein 14 COX16 PF14138.6 KKK22519.1 - 6.6 7.3 11.3 12 6.5 11.3 1.5 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein COX16 GAS PF13851.6 KKK22520.1 - 0.00029 20.3 1.2 0.00045 19.6 1.2 1.2 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding AAA_13 PF13166.6 KKK22520.1 - 0.001 17.8 0.6 0.0013 17.4 0.6 1.0 1 0 0 1 1 1 1 AAA domain Spc7 PF08317.11 KKK22520.1 - 0.0012 17.8 0.9 0.0018 17.2 0.9 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF3287 PF11690.8 KKK22520.1 - 0.014 15.1 0.2 0.027 14.2 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3287) Phlebovirus_NSM PF07246.11 KKK22520.1 - 0.061 12.7 0.7 0.1 11.9 0.7 1.3 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M OmpH PF03938.14 KKK22520.1 - 0.12 12.7 1.4 0.21 11.9 1.4 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) T2SSF PF00482.23 KKK22520.1 - 0.13 12.3 0.3 0.26 11.2 0.3 1.5 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F TEX13 PF15186.6 KKK22520.1 - 0.14 11.8 3.7 0.2 11.3 2.8 1.6 1 1 0 1 1 1 0 Testis-expressed sequence 13 protein family CtIP_N PF10482.9 KKK22520.1 - 0.17 12.0 2.3 0.31 11.1 2.3 1.3 1 0 0 1 1 1 0 Tumour-suppressor protein CtIP N-terminal domain DUF1664 PF07889.12 KKK22520.1 - 0.19 11.8 0.4 2.3 8.3 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) EMP24_GP25L PF01105.24 KKK22520.1 - 0.23 11.4 1.1 0.42 10.5 1.1 1.4 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD DUF1488 PF07369.11 KKK22520.1 - 0.26 11.3 1.1 5.9 7.0 1.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1488) DUF16 PF01519.16 KKK22520.1 - 0.41 11.1 5.3 0.53 10.8 2.2 2.1 2 0 0 2 2 2 0 Protein of unknown function DUF16 Brix PF04427.18 KKK22523.1 - 1.7e-30 106.6 0.0 2.2e-30 106.2 0.0 1.1 1 0 0 1 1 1 1 Brix domain UPF1_Zn_bind PF09416.10 KKK22524.1 - 1.2e-72 242.9 1.6 3.4e-72 241.4 1.4 1.9 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.6 KKK22524.1 - 9.8e-60 201.6 0.0 1.5e-59 201.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KKK22524.1 - 1.3e-54 185.7 2.3 1.3e-31 110.3 0.2 2.3 1 1 1 2 2 2 2 AAA domain DUF5599 PF18141.1 KKK22524.1 - 2.2e-33 114.4 0.0 4.7e-33 113.3 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF5599) AAA_30 PF13604.6 KKK22524.1 - 1.5e-13 50.9 0.2 2.3e-12 47.0 0.2 2.4 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KKK22524.1 - 3.4e-11 43.7 0.0 1.9e-10 41.2 0.0 2.2 2 1 0 2 2 2 1 AAA domain ResIII PF04851.15 KKK22524.1 - 1.1e-05 25.5 0.0 2.1e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.18 KKK22524.1 - 7e-05 22.7 0.2 0.71 9.6 0.0 2.9 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.14 KKK22524.1 - 0.00058 19.8 0.0 0.0012 18.7 0.0 1.6 1 0 0 1 1 1 1 Helicase DUF2075 PF09848.9 KKK22524.1 - 0.0018 17.6 0.1 0.033 13.4 0.0 2.5 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) PIF1 PF05970.14 KKK22524.1 - 0.0026 17.0 0.1 0.43 9.7 0.0 2.2 2 0 0 2 2 2 1 PIF1-like helicase UvrD-helicase PF00580.21 KKK22524.1 - 0.0081 15.7 0.1 0.057 12.9 0.0 2.2 2 1 0 3 3 3 1 UvrD/REP helicase N-terminal domain DEAD PF00270.29 KKK22524.1 - 0.01 15.6 0.0 0.022 14.5 0.0 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase AAA_10 PF12846.7 KKK22524.1 - 0.025 13.5 0.0 0.043 12.7 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain ATPase PF06745.13 KKK22524.1 - 0.038 13.3 0.0 0.085 12.2 0.0 1.5 1 0 0 1 1 1 0 KaiC AAA_22 PF13401.6 KKK22524.1 - 0.068 13.4 0.1 0.22 11.8 0.1 1.9 1 1 0 1 1 1 0 AAA domain Ribosomal_S27e PF01667.17 KKK22524.1 - 1.1 9.1 3.4 1.3 8.8 0.8 2.3 2 0 0 2 2 2 0 Ribosomal protein S27 zf-RanBP PF00641.18 KKK22524.1 - 3.9 6.9 7.4 0.44 9.9 2.3 2.0 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others Homeodomain PF00046.29 KKK22526.1 - 1.3e-16 60.1 4.1 2.3e-16 59.3 4.1 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KKK22526.1 - 0.23 11.4 0.2 0.23 11.4 0.2 1.9 2 0 0 2 2 2 0 Homeobox KN domain ADH_zinc_N PF00107.26 KKK22528.1 - 7.8e-05 22.7 0.0 0.00014 21.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KKK22528.1 - 9.4e-05 23.5 0.1 0.00011 23.2 0.1 1.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Fungal_lectin_2 PF18647.1 KKK22529.1 - 7.2e-27 93.8 0.1 8.7e-26 90.4 0.0 2.3 2 0 0 2 2 2 1 Alpha-galactosyl-binding fungal lectin Lipase_GDSL_2 PF13472.6 KKK22529.1 - 2.5e-14 54.1 0.2 3.9e-12 46.9 0.0 2.4 2 0 0 2 2 2 2 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KKK22529.1 - 1.7e-07 31.4 0.0 2e-06 27.9 0.0 2.2 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Glyco_hydro_18 PF00704.28 KKK22530.1 - 3.5e-26 92.7 0.0 4.5e-26 92.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Acetyltransf_13 PF13880.6 KKK22531.1 - 3.9e-30 103.6 0.0 8.9e-30 102.5 0.0 1.7 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.6 KKK22531.1 - 1.7e-15 56.5 0.6 3e-15 55.7 0.6 1.4 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO TolA_bind_tri PF16331.5 KKK22532.1 - 0.16 12.0 0.0 0.3 11.2 0.0 1.4 1 0 0 1 1 1 0 TolA binding protein trimerisation Haspin_kinase PF12330.8 KKK22532.1 - 1.2 8.0 2.8 1.7 7.5 2.8 1.1 1 0 0 1 1 1 0 Haspin like kinase domain EMG1 PF03587.14 KKK22533.1 - 1.2e-80 269.8 0.0 1.4e-80 269.6 0.0 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase Peptidase_C107 PF17222.3 KKK22533.1 - 0.12 11.3 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 Viral cysteine endopeptidase C107 GFA PF04828.14 KKK22534.1 - 0.0041 17.4 0.6 0.0079 16.5 0.0 1.9 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme V-SNARE PF05008.15 KKK22535.1 - 0.35 11.3 2.5 0.84 10.0 2.5 1.6 1 0 0 1 1 1 0 Vesicle transport v-SNARE protein N-terminus CybS PF05328.12 KKK22536.1 - 1.3e-53 180.2 0.0 1.7e-53 179.9 0.0 1.1 1 0 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit Maf PF02545.14 KKK22537.1 - 2.3e-47 161.0 0.1 4.6e-47 160.0 0.1 1.5 2 0 0 2 2 2 1 Maf-like protein HLH PF00010.26 KKK22537.1 - 2.4e-07 30.6 0.0 2.4e-07 30.6 0.0 1.9 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain NOA36 PF06524.12 KKK22537.1 - 6.7 5.9 8.4 0.25 10.6 2.8 1.5 2 0 0 2 2 2 0 NOA36 protein ADH_zinc_N PF00107.26 KKK22538.1 - 2.9e-21 75.8 0.0 4.4e-21 75.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 KKK22538.1 - 3.4e-08 33.3 0.0 6.4e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 KKK22538.1 - 1.1e-06 29.7 0.0 2.4e-06 28.6 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Fungal_trans PF04082.18 KKK22539.1 - 4.8e-10 38.9 0.3 1.9e-09 37.0 0.1 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain DUF1338 PF07063.13 KKK22540.1 - 4.9e-111 371.0 0.3 6e-111 370.7 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1338) Cyc-maltodext_C PF10438.9 KKK22540.1 - 0.1 12.7 0.1 2.9 8.1 0.0 2.7 2 1 0 2 2 2 0 Cyclo-malto-dextrinase C-terminal domain Slx4 PF09494.10 KKK22540.1 - 0.13 12.2 0.0 0.59 10.1 0.0 2.2 1 0 0 1 1 1 0 Slx4 endonuclease Ribosomal_L21p PF00829.21 KKK22541.1 - 1.5e-08 34.8 0.1 3.2e-08 33.8 0.0 1.6 2 0 0 2 2 2 1 Ribosomal prokaryotic L21 protein RIB43A PF05914.12 KKK22541.1 - 0.017 13.9 0.4 0.022 13.5 0.4 1.1 1 0 0 1 1 1 0 RIB43A ORC6 PF05460.13 KKK22541.1 - 1.3 8.2 9.5 1.9 7.7 9.5 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Ribosomal_S8e PF01201.22 KKK22542.1 - 1.7e-46 157.8 2.4 2.8e-46 157.1 2.4 1.3 1 0 0 1 1 1 1 Ribosomal protein S8e Pannexin_like PF12534.8 KKK22542.1 - 7.3 5.6 6.7 10 5.1 6.7 1.1 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 Pkinase PF00069.25 KKK22544.1 - 1.2e-46 159.2 0.0 1.9e-46 158.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK22544.1 - 2.9e-17 62.8 0.0 4.5e-17 62.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 KKK22544.1 - 0.0027 17.3 0.2 0.0052 16.4 0.2 1.4 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 KKK22544.1 - 0.017 14.4 0.1 0.031 13.6 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KKK22544.1 - 0.031 13.6 0.0 0.052 12.9 0.0 1.3 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 KKK22544.1 - 0.071 13.0 0.1 0.57 10.1 0.1 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KKK22544.1 - 0.09 11.5 0.0 0.09 11.5 0.0 2.0 2 0 0 2 2 2 0 Fungal protein kinase PsaA_PsaB PF00223.19 KKK22544.1 - 0.19 9.9 0.0 0.28 9.3 0.0 1.1 1 0 0 1 1 1 0 Photosystem I psaA/psaB protein MTCP1 PF08991.10 KKK22545.1 - 0.023 14.9 0.2 0.041 14.1 0.2 1.4 1 0 0 1 1 1 0 Mature-T-Cell Proliferation I type MIEAP PF16026.5 KKK22545.1 - 0.05 13.8 0.1 0.066 13.4 0.1 1.1 1 0 0 1 1 1 0 Mitochondria-eating protein CHCH PF06747.13 KKK22545.1 - 0.17 12.0 5.0 0.24 11.6 1.6 2.4 2 1 0 2 2 2 0 CHCH domain BAR_2 PF10455.9 KKK22546.1 - 0.21 10.7 1.4 0.36 9.9 1.4 1.3 1 0 0 1 1 1 0 Bin/amphiphysin/Rvs domain for vesicular trafficking Ribosomal_L36e PF01158.18 KKK22547.1 - 1e-24 86.6 0.2 1.2e-24 86.4 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e CRCB PF02537.15 KKK22548.1 - 0.084 13.2 0.1 0.16 12.3 0.1 1.4 1 0 0 1 1 1 0 CrcB-like protein, Camphor Resistance (CrcB) NatB_MDM20 PF09797.9 KKK22549.1 - 1.1e-108 363.6 0.0 2e-108 362.7 0.0 1.4 1 0 0 1 1 1 1 N-acetyltransferase B complex (NatB) non catalytic subunit TPR_19 PF14559.6 KKK22549.1 - 0.00029 21.3 0.1 0.00029 21.3 0.1 3.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 KKK22549.1 - 0.033 14.8 2.5 6.5 7.5 1.6 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 KKK22549.1 - 0.089 13.7 3.0 31 5.7 0.1 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF4363 PF14276.6 KKK22549.1 - 1.3 9.2 4.2 3.9 7.6 0.2 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4363) zf-C3HC4 PF00097.25 KKK22550.1 - 1.7e-08 34.2 4.6 1.7e-08 34.2 4.6 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KKK22550.1 - 6.8e-08 32.7 6.4 6.8e-08 32.7 6.4 2.5 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.6 KKK22550.1 - 8.3e-08 32.0 3.0 8.3e-08 32.0 3.0 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KKK22550.1 - 5.6e-07 29.6 7.5 5.6e-07 29.6 7.5 2.3 2 1 1 3 3 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 KKK22550.1 - 1.3e-06 28.1 6.3 1.3e-06 28.1 6.3 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KKK22550.1 - 3.2e-06 27.1 6.3 9.1e-06 25.6 6.3 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KKK22550.1 - 6e-06 26.1 5.6 6e-06 26.1 5.6 2.6 3 0 0 3 3 3 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KKK22550.1 - 0.0086 15.9 4.6 0.0086 15.9 4.6 2.4 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_6 PF14835.6 KKK22550.1 - 0.0091 15.8 3.0 0.0091 15.8 3.0 2.1 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-rbx1 PF12678.7 KKK22550.1 - 0.01 16.1 6.1 0.01 16.1 6.1 2.5 2 1 0 2 2 2 0 RING-H2 zinc finger domain Radial_spoke PF04712.12 KKK22550.1 - 0.016 14.2 7.9 0.03 13.3 7.9 1.3 1 0 0 1 1 1 0 Radial spokehead-like protein zf-RING_4 PF14570.6 KKK22550.1 - 0.023 14.5 5.3 0.065 13.0 2.6 2.7 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain DZR PF12773.7 KKK22550.1 - 0.063 13.3 9.3 4 7.5 0.1 2.9 2 1 0 2 2 2 0 Double zinc ribbon zf-ANAPC11 PF12861.7 KKK22550.1 - 0.56 10.3 6.0 0.084 12.9 0.9 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 KKK22550.1 - 1.7 8.4 4.7 5.9 6.7 4.7 2.0 1 1 0 1 1 1 0 RING-like zinc finger zinc_ribbon_2 PF13240.6 KKK22550.1 - 2.2 8.1 10.7 11 5.9 0.0 4.1 4 0 0 4 4 4 0 zinc-ribbon domain zf-ribbon_3 PF13248.6 KKK22550.1 - 2.4 7.7 6.8 2.6 7.6 0.9 3.1 2 0 0 2 2 2 0 zinc-ribbon domain zinc-ribbons_6 PF07191.12 KKK22550.1 - 6.7 6.8 7.5 18 5.4 0.3 2.5 2 0 0 2 2 2 0 zinc-ribbons MFS_1 PF07690.16 KKK22551.1 - 0.0001 21.4 5.1 0.0031 16.5 1.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Ank_4 PF13637.6 KKK22567.1 - 2e-54 181.3 5.2 8.8e-10 38.9 0.0 11.6 6 3 8 14 14 13 11 Ankyrin repeats (many copies) Ank_2 PF12796.7 KKK22567.1 - 2.3e-52 175.5 1.1 3.1e-13 50.1 0.0 7.1 1 1 5 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.30 KKK22567.1 - 1.3e-44 148.7 8.2 1.6e-05 25.1 0.0 11.5 11 0 0 11 11 11 9 Ankyrin repeat Ank_3 PF13606.6 KKK22567.1 - 4.2e-39 128.1 6.5 3.3e-05 23.9 0.0 12.7 13 0 0 13 13 12 9 Ankyrin repeat Ank_5 PF13857.6 KKK22567.1 - 3.1e-38 129.3 6.5 3.3e-08 33.7 0.0 9.1 8 1 1 9 9 9 6 Ankyrin repeats (many copies) NACHT PF05729.12 KKK22567.1 - 7.1e-08 32.5 0.0 2e-07 31.1 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 KKK22567.1 - 7.7e-08 32.7 0.0 1.9e-07 31.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 KKK22567.1 - 0.00037 20.9 0.0 0.0013 19.2 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KKK22567.1 - 0.0004 20.8 0.0 0.0011 19.3 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 KKK22567.1 - 0.005 17.0 0.0 0.013 15.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 KKK22567.1 - 0.12 12.8 0.0 5 7.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain Asp_protease_2 PF13650.6 KKK22567.1 - 0.12 13.0 0.0 0.68 10.6 0.0 2.3 2 0 0 2 2 1 0 Aspartyl protease AAA_7 PF12775.7 KKK22567.1 - 0.13 11.8 0.0 0.28 10.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region NB-ARC PF00931.22 KKK22567.1 - 0.16 11.1 0.0 0.31 10.2 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Fungal_trans_2 PF11951.8 KKK22569.1 - 2.6e-82 276.7 0.0 3.4e-82 276.3 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK22569.1 - 2.9e-07 30.5 7.0 2.9e-07 30.5 7.0 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SAM_2 PF07647.17 KKK22570.1 - 1.4e-10 41.1 0.1 2.7e-10 40.2 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KKK22570.1 - 1.4e-09 38.3 0.4 4.2e-09 36.7 0.1 2.0 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) PH PF00169.29 KKK22570.1 - 3.4e-06 27.5 1.6 1.2e-05 25.8 0.7 2.5 3 1 0 3 3 3 1 PH domain SAM_Ste50p PF09235.10 KKK22570.1 - 2.9e-05 24.2 0.0 6.4e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Ste50p, sterile alpha motif SAM_3 PF18016.1 KKK22570.1 - 0.00054 19.7 0.1 0.0016 18.2 0.1 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 KKK22570.1 - 0.076 13.0 0.0 0.34 10.9 0.0 2.0 2 0 0 2 2 2 0 Sterile alpha motif (SAM)/Pointed domain PH_10 PF15411.6 KKK22573.1 - 2.3e-28 98.9 0.2 4.2e-28 98.1 0.2 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain VWA PF00092.28 KKK22573.1 - 1.2e-13 51.7 0.0 2.2e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 KKK22573.1 - 2.2e-10 40.7 0.0 1.4e-09 38.1 0.0 2.3 2 1 0 2 2 2 1 von Willebrand factor type A domain VWA_2 PF13519.6 KKK22573.1 - 2e-06 28.4 0.0 6.7e-06 26.7 0.0 1.9 1 0 0 1 1 1 1 von Willebrand factor type A domain zf-RING_2 PF13639.6 KKK22573.1 - 0.0002 21.6 4.1 0.00038 20.7 4.1 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 KKK22573.1 - 0.00042 20.2 4.2 0.00073 19.4 4.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KKK22573.1 - 0.0032 17.3 4.0 0.0059 16.4 4.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KKK22573.1 - 0.0066 16.3 4.2 0.012 15.5 4.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 KKK22573.1 - 0.0076 15.8 3.3 0.0076 15.8 3.3 1.9 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-RING-like PF08746.11 KKK22573.1 - 0.016 15.5 4.3 0.03 14.6 4.3 1.5 1 0 0 1 1 1 0 RING-like domain zf-rbx1 PF12678.7 KKK22573.1 - 0.045 14.0 1.9 0.097 13.0 1.9 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain PH PF00169.29 KKK22573.1 - 0.047 14.2 0.2 0.12 12.9 0.2 1.7 1 0 0 1 1 1 0 PH domain zf-UDP PF14569.6 KKK22573.1 - 0.1 12.8 0.8 0.17 12.0 0.8 1.3 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-RING_11 PF17123.5 KKK22573.1 - 0.45 10.3 3.3 0.93 9.3 3.3 1.6 1 0 0 1 1 1 0 RING-like zinc finger zf-C3H2C3 PF17122.5 KKK22573.1 - 0.52 10.4 4.7 1.2 9.3 4.7 1.6 1 0 0 1 1 1 0 Zinc-finger PHD PF00628.29 KKK22573.1 - 2.2 8.2 3.7 3.9 7.4 3.7 1.4 1 0 0 1 1 1 0 PHD-finger Fungal_trans PF04082.18 KKK22574.1 - 5.4e-06 25.6 0.5 1.1e-05 24.6 0.5 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain p450 PF00067.22 KKK22575.1 - 1.2e-11 44.0 0.1 0.0001 21.2 0.0 3.2 1 1 1 2 2 2 2 Cytochrome P450 TPR_12 PF13424.6 KKK22576.1 - 1.9e-09 37.7 29.7 0.00081 19.6 0.1 9.1 10 0 0 10 10 10 4 Tetratricopeptide repeat AAA_22 PF13401.6 KKK22576.1 - 1.5e-06 28.6 0.2 0.0024 18.2 0.0 3.3 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 KKK22576.1 - 6.3e-06 26.2 0.0 2.7e-05 24.1 0.0 2.1 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KKK22576.1 - 8.5e-05 23.0 0.2 0.0012 19.3 0.0 3.2 2 0 0 2 2 2 1 AAA ATPase domain TPR_19 PF14559.6 KKK22576.1 - 0.053 14.0 11.5 0.33 11.5 0.1 6.3 6 1 1 7 7 7 0 Tetratricopeptide repeat NB-ARC PF00931.22 KKK22576.1 - 0.086 12.0 0.0 0.21 10.8 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain TPR_14 PF13428.6 KKK22576.1 - 0.11 13.4 21.2 6.1 8.0 0.0 8.0 9 0 0 9 9 9 0 Tetratricopeptide repeat GCN5L1 PF06320.13 KKK22576.1 - 6.7 6.9 6.9 0.72 10.0 0.0 3.0 3 0 0 3 3 3 0 GCN5-like protein 1 (GCN5L1) Abhydrolase_3 PF07859.13 KKK22577.1 - 3.1e-55 187.3 0.0 4.1e-55 186.9 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KKK22577.1 - 7e-07 28.4 0.0 9.2e-07 28.0 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase Chlorophyllase2 PF12740.7 KKK22577.1 - 0.00011 21.2 0.2 0.00027 20.0 0.2 1.5 1 1 0 1 1 1 1 Chlorophyllase enzyme LIDHydrolase PF10230.9 KKK22577.1 - 0.00026 20.7 0.0 0.00038 20.1 0.0 1.2 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase COesterase PF00135.28 KKK22577.1 - 0.0013 17.7 0.1 0.015 14.2 0.0 2.1 2 0 0 2 2 2 1 Carboxylesterase family Esterase PF00756.20 KKK22577.1 - 0.021 14.4 0.2 0.21 11.2 0.2 2.0 1 1 0 1 1 1 0 Putative esterase Hydrolase_4 PF12146.8 KKK22577.1 - 0.034 13.4 0.0 0.11 11.7 0.0 1.7 1 1 1 2 2 2 0 Serine aminopeptidase, S33 Glyco_transf_28 PF03033.20 KKK22578.1 - 5.8e-17 62.0 0.7 2.6e-13 50.2 0.1 2.3 2 0 0 2 2 2 2 Glycosyltransferase family 28 N-terminal domain ATG_C PF09333.11 KKK22578.1 - 0.00068 19.9 0.0 0.0022 18.3 0.0 1.8 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain Glyco_hydro_76 PF03663.14 KKK22580.1 - 2.4e-140 468.2 22.5 3e-140 467.9 22.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Cation_efflux PF01545.21 KKK22581.1 - 2.4e-49 167.8 7.2 3.2e-49 167.4 7.2 1.1 1 0 0 1 1 1 1 Cation efflux family BPD_transp_2 PF02653.16 KKK22581.1 - 0.00049 19.3 0.0 0.00049 19.3 0.0 1.8 2 1 0 1 1 1 1 Branched-chain amino acid transport system / permease component Pyr_redox_2 PF07992.14 KKK22582.1 - 4e-26 91.9 0.0 9.1e-22 77.6 0.0 2.1 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KKK22582.1 - 2.6e-16 60.0 0.0 3.8e-12 46.6 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KKK22582.1 - 1.7e-06 27.5 0.1 2.9e-06 26.7 0.1 1.3 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 KKK22582.1 - 4.2e-06 26.6 0.6 0.059 12.9 0.1 2.6 2 1 0 2 2 2 2 FAD dependent oxidoreductase TrkA_N PF02254.18 KKK22582.1 - 9e-05 22.7 0.0 0.09 13.0 0.0 2.8 3 0 0 3 3 3 2 TrkA-N domain NAD_binding_8 PF13450.6 KKK22582.1 - 9.2e-05 22.6 0.0 0.46 10.7 0.0 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KKK22582.1 - 0.00012 21.4 0.0 0.00046 19.6 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KKK22582.1 - 0.00025 20.1 0.0 0.24 10.2 0.0 2.1 2 0 0 2 2 2 2 Tryptophan halogenase NAD_binding_7 PF13241.6 KKK22582.1 - 0.00047 20.6 0.0 0.086 13.3 0.0 2.4 2 0 0 2 2 2 1 Putative NAD(P)-binding DUF1188 PF06690.11 KKK22582.1 - 0.0072 15.9 0.0 2.9 7.4 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1188) NAD_binding_9 PF13454.6 KKK22582.1 - 0.015 15.3 0.3 28 4.6 0.0 3.2 3 0 0 3 3 3 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 KKK22582.1 - 0.096 11.7 0.0 0.55 9.2 0.0 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein APH PF01636.23 KKK22583.1 - 0.002 18.1 0.0 0.002 18.1 0.0 3.1 2 1 0 2 2 1 1 Phosphotransferase enzyme family DDHD PF02862.17 KKK22583.1 - 0.02 15.0 9.1 0.82 9.8 3.0 2.4 2 0 0 2 2 2 0 DDHD domain HSDR_N_2 PF13588.6 KKK22583.1 - 0.031 14.3 0.1 0.27 11.2 0.1 2.3 2 0 0 2 2 2 0 Type I restriction enzyme R protein N terminus (HSDR_N) Pkinase_Tyr PF07714.17 KKK22583.1 - 0.086 12.1 0.0 0.16 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein tyrosine kinase CDC45 PF02724.14 KKK22583.1 - 0.15 10.3 21.2 0.62 8.3 2.7 2.2 2 0 0 2 2 2 0 CDC45-like protein SpoIIIAH PF12685.7 KKK22583.1 - 0.74 9.6 10.3 3.5 7.4 2.8 2.3 2 0 0 2 2 2 0 SpoIIIAH-like protein RNA_pol_Rpc4 PF05132.14 KKK22583.1 - 3.5 8.0 16.8 2.2 8.7 0.5 2.4 2 0 0 2 2 2 0 RNA polymerase III RPC4 RP-C_C PF11800.8 KKK22583.1 - 4.1 7.4 21.2 4.4 7.3 9.4 2.5 2 0 0 2 2 2 0 Replication protein C C-terminal region AAR2 PF05282.11 KKK22583.1 - 5.3 6.3 9.5 4.7 6.5 0.9 2.3 2 0 0 2 2 2 0 AAR2 protein Tim54 PF11711.8 KKK22583.1 - 5.8 5.6 18.6 0.72 8.6 7.1 2.2 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 eIF3_subunit PF08597.10 KKK22583.1 - 7.1 6.5 26.8 0.19 11.6 14.0 2.4 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit GST_C_2 PF13410.6 KKK22584.1 - 2.8e-08 33.7 0.3 1.1e-07 31.8 0.3 2.0 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KKK22584.1 - 1.4e-06 28.5 0.0 3.2e-06 27.3 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KKK22584.1 - 3.9e-05 24.0 0.0 7.2e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KKK22584.1 - 6.8e-05 23.0 0.0 0.00012 22.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 KKK22584.1 - 0.0044 17.7 0.0 0.011 16.4 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase N-terminal domain FAD_binding_3 PF01494.19 KKK22586.1 - 3.4e-30 105.5 0.0 3.7e-29 102.1 0.0 1.9 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KKK22586.1 - 9.7e-08 31.6 0.2 0.0004 19.7 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KKK22586.1 - 1.1e-06 28.5 0.8 0.0015 18.2 0.2 2.2 1 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KKK22586.1 - 1.8e-05 24.8 0.0 3.9e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KKK22586.1 - 4.8e-05 22.8 0.1 0.005 16.1 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 KKK22586.1 - 8.7e-05 21.7 0.0 0.0046 16.0 0.0 2.1 2 0 0 2 2 2 1 Squalene epoxidase Trp_halogenase PF04820.14 KKK22586.1 - 0.0003 19.8 0.1 0.77 8.5 0.0 2.9 3 0 0 3 3 3 2 Tryptophan halogenase HI0933_like PF03486.14 KKK22586.1 - 0.00035 19.4 0.0 0.019 13.7 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.24 KKK22586.1 - 0.0014 17.8 0.0 0.0029 16.7 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 KKK22586.1 - 0.0015 17.6 0.4 0.035 13.2 0.0 2.5 3 0 0 3 3 3 1 Lycopene cyclase protein NAD_binding_9 PF13454.6 KKK22586.1 - 0.023 14.7 0.3 0.094 12.7 0.1 2.0 2 0 0 2 2 2 0 FAD-NAD(P)-binding Thi4 PF01946.17 KKK22586.1 - 0.067 12.4 0.1 0.11 11.7 0.1 1.3 1 0 0 1 1 1 0 Thi4 family Cu_bind_CorA PF18252.1 KKK22586.1 - 0.075 12.7 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Copper(I)-binding protein CorA Pyr_redox PF00070.27 KKK22586.1 - 0.14 12.7 0.0 15 6.2 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AAA PF00004.29 KKK22592.1 - 1.9e-97 322.8 0.0 2.8e-47 160.5 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KKK22592.1 - 1.3e-23 82.5 2.2 1e-12 47.7 0.3 2.8 2 0 0 2 2 2 2 AAA+ lid domain RuvB_N PF05496.12 KKK22592.1 - 1.9e-14 53.7 0.0 5.1e-06 26.3 0.0 3.2 3 1 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 KKK22592.1 - 2e-14 54.1 0.0 8.1e-08 32.6 0.0 2.8 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 KKK22592.1 - 1.2e-12 48.2 0.0 1.7e-05 25.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KKK22592.1 - 1.3e-12 48.4 0.0 0.00016 22.1 0.0 4.5 3 2 1 4 4 3 2 AAA ATPase domain AAA_5 PF07728.14 KKK22592.1 - 1.4e-11 44.6 0.6 1.5e-05 25.0 0.1 3.8 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KKK22592.1 - 1.6e-09 38.1 0.3 0.023 15.0 0.0 4.2 2 2 1 3 3 3 2 AAA domain TIP49 PF06068.13 KKK22592.1 - 2.7e-09 36.7 0.0 0.001 18.4 0.0 2.6 2 0 0 2 2 2 2 TIP49 P-loop domain CDC48_2 PF02933.17 KKK22592.1 - 3.6e-09 36.3 0.0 8.4e-09 35.1 0.0 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 Mg_chelatase PF01078.21 KKK22592.1 - 9.6e-08 31.6 0.7 0.0085 15.5 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 KKK22592.1 - 4.3e-07 30.3 0.0 0.024 15.0 0.0 2.8 2 0 0 2 2 2 2 RNA helicase IstB_IS21 PF01695.17 KKK22592.1 - 4.3e-07 29.8 0.0 0.016 14.9 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein Vps4_C PF09336.10 KKK22592.1 - 4.7e-07 29.7 0.1 8.8e-06 25.6 0.1 2.6 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_18 PF13238.6 KKK22592.1 - 5e-07 30.3 0.0 0.023 15.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.6 KKK22592.1 - 7e-07 29.3 0.0 0.013 15.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain ATPase PF06745.13 KKK22592.1 - 1.3e-06 28.0 0.3 0.42 9.9 0.0 3.3 3 0 0 3 3 3 2 KaiC AAA_25 PF13481.6 KKK22592.1 - 3.2e-06 26.9 3.2 0.27 10.8 0.1 3.8 2 2 2 4 4 4 2 AAA domain AAA_7 PF12775.7 KKK22592.1 - 4.1e-06 26.4 0.1 0.045 13.3 0.0 3.3 3 2 0 3 3 2 2 P-loop containing dynein motor region AAA_24 PF13479.6 KKK22592.1 - 5.1e-06 26.4 0.0 0.11 12.2 0.0 2.8 3 0 0 3 3 2 2 AAA domain Parvo_NS1 PF01057.17 KKK22592.1 - 1.1e-05 24.7 0.1 0.044 12.9 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_28 PF13521.6 KKK22592.1 - 1.5e-05 25.3 0.1 0.15 12.3 0.0 2.8 3 0 0 3 3 2 2 AAA domain DUF815 PF05673.13 KKK22592.1 - 1.7e-05 24.1 0.0 0.014 14.6 0.0 2.5 2 1 0 2 2 2 2 Protein of unknown function (DUF815) Sigma54_activat PF00158.26 KKK22592.1 - 1.9e-05 24.5 0.1 0.33 10.6 0.0 3.3 2 2 0 2 2 2 2 Sigma-54 interaction domain Bac_DnaA PF00308.18 KKK22592.1 - 8.1e-05 22.6 0.0 0.21 11.4 0.0 2.5 2 0 0 2 2 2 2 Bacterial dnaA protein ABC_tran PF00005.27 KKK22592.1 - 8.7e-05 23.1 0.0 0.44 11.1 0.0 3.3 2 1 0 2 2 2 1 ABC transporter TsaE PF02367.17 KKK22592.1 - 0.00012 22.1 0.0 0.27 11.2 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE ResIII PF04851.15 KKK22592.1 - 0.00012 22.2 0.0 0.061 13.3 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_11 PF13086.6 KKK22592.1 - 0.00015 21.7 0.3 0.68 9.7 0.1 2.8 2 1 0 2 2 2 2 AAA domain AAA_17 PF13207.6 KKK22592.1 - 0.00016 22.1 0.0 0.48 10.9 0.0 2.9 3 0 0 3 3 2 2 AAA domain NACHT PF05729.12 KKK22592.1 - 0.0002 21.4 0.1 0.14 12.0 0.0 2.9 3 0 0 3 3 3 1 NACHT domain PhoH PF02562.16 KKK22592.1 - 0.00022 20.8 0.4 0.58 9.6 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein AAA_3 PF07726.11 KKK22592.1 - 0.00026 20.8 0.0 0.87 9.4 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 KKK22592.1 - 0.00047 20.1 0.0 2 8.3 0.0 3.5 3 1 0 3 3 3 1 ATPase domain predominantly from Archaea AAA_30 PF13604.6 KKK22592.1 - 0.00062 19.5 0.3 0.7 9.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain DUF2075 PF09848.9 KKK22592.1 - 0.0012 18.2 0.0 1.1 8.4 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.6 KKK22592.1 - 0.0024 18.2 0.4 4.4 7.6 0.0 3.4 3 1 1 4 4 4 0 AAA domain Viral_helicase1 PF01443.18 KKK22592.1 - 0.0036 17.1 0.0 0.29 10.9 0.0 2.3 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase NTPase_1 PF03266.15 KKK22592.1 - 0.0059 16.5 0.5 2.1 8.2 0.0 3.7 3 0 0 3 3 3 1 NTPase NB-ARC PF00931.22 KKK22592.1 - 0.0074 15.5 0.0 1.3 8.1 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain KAP_NTPase PF07693.14 KKK22592.1 - 0.0079 15.5 0.4 0.73 9.0 0.0 3.0 2 2 2 4 4 4 1 KAP family P-loop domain Zeta_toxin PF06414.12 KKK22592.1 - 0.0079 15.5 0.0 4.8 6.4 0.0 2.6 2 0 0 2 2 2 0 Zeta toxin IPT PF01745.16 KKK22592.1 - 0.012 15.0 0.0 2 7.8 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase Sigma54_activ_2 PF14532.6 KKK22592.1 - 0.018 15.1 0.0 3 8.0 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain Zot PF05707.12 KKK22592.1 - 0.021 14.5 0.2 1.6 8.4 0.0 3.3 2 2 1 3 3 3 0 Zonular occludens toxin (Zot) Cytidylate_kin PF02224.18 KKK22592.1 - 0.042 13.6 0.0 8.3 6.1 0.0 2.7 2 0 0 2 2 2 0 Cytidylate kinase AFG1_ATPase PF03969.16 KKK22592.1 - 0.047 12.6 0.0 7.8 5.3 0.0 2.3 2 0 0 2 2 2 0 AFG1-like ATPase AAA_6 PF12774.7 KKK22592.1 - 0.048 12.6 0.3 7.5 5.4 0.0 2.5 3 0 0 3 3 2 0 Hydrolytic ATP binding site of dynein motor region Cytidylate_kin2 PF13189.6 KKK22592.1 - 0.062 13.4 0.0 4.3 7.4 0.0 2.5 2 0 0 2 2 2 0 Cytidylate kinase-like family EnY2 PF10163.9 KKK22593.1 - 0.00063 20.1 0.0 0.0011 19.3 0.0 1.4 1 0 0 1 1 1 1 Transcription factor e(y)2 RRM_Rrp7 PF17799.1 KKK22596.1 - 1e-31 110.0 0.0 1.8e-31 109.1 0.0 1.5 1 0 0 1 1 1 1 Rrp7 RRM-like N-terminal domain RRP7 PF12923.7 KKK22596.1 - 5.5e-27 94.3 10.9 5.5e-27 94.3 10.9 2.5 3 0 0 3 3 3 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain Dak1_2 PF13684.6 KKK22596.1 - 0.33 10.0 3.9 1.4 7.9 0.1 2.4 1 1 2 3 3 3 0 Dihydroxyacetone kinase family baeRF_family7 PF18849.1 KKK22596.1 - 1.9 8.7 4.9 0.34 11.1 0.5 1.9 2 0 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 7 TFB6 PF17110.5 KKK22597.1 - 1.7e-57 193.9 0.3 2.8e-57 193.2 0.0 1.4 2 0 0 2 2 2 1 Subunit 11 of the general transcription factor TFIIH DUF2458 PF10454.9 KKK22598.1 - 3.6e-27 95.1 4.7 3.6e-27 95.1 4.7 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2458) DUF737 PF05300.11 KKK22598.1 - 0.12 12.7 3.2 0.16 12.3 3.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF737) DUF2890 PF11081.8 KKK22598.1 - 0.12 12.4 5.3 0.15 12.2 5.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) DAHP_synth_1 PF00793.20 KKK22599.1 - 6.1e-101 336.9 0.0 7.6e-101 336.6 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family COX14 PF14880.6 KKK22600.1 - 5.6e-20 70.9 0.5 5.6e-20 70.9 0.5 1.7 2 0 0 2 2 2 1 Cytochrome oxidase c assembly DUF2656 PF10847.8 KKK22600.1 - 0.018 15.1 0.3 0.046 13.8 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2656) Gluconate_2-dh3 PF13618.6 KKK22600.1 - 0.071 13.3 2.1 0.56 10.4 1.0 2.6 1 1 1 2 2 2 0 Gluconate 2-dehydrogenase subunit 3 FOXO_KIX_bdg PF16675.5 KKK22600.1 - 0.1 12.9 0.6 2.5 8.5 0.0 2.5 2 0 0 2 2 2 0 KIX-binding domain of forkhead box O, CR2 Dehydrin PF00257.19 KKK22600.1 - 6.8 7.2 9.9 16 6.0 0.0 2.8 2 1 0 2 2 2 0 Dehydrin adh_short PF00106.25 KKK22601.1 - 4.5e-13 49.1 0.0 3.3e-08 33.2 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KKK22601.1 - 4.8e-08 32.8 0.0 6e-06 26.0 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KKK22601.1 - 0.00023 21.1 0.0 0.00034 20.6 0.0 1.3 1 0 0 1 1 1 1 KR domain Pdase_M17_N2 PF18295.1 KKK22601.1 - 0.084 13.1 0.2 0.2 11.9 0.1 1.6 2 0 0 2 2 2 0 M17 aminopeptidase N-terminal domain 2 Thiolase_N PF00108.23 KKK22602.1 - 1e-74 251.2 0.2 1.4e-74 250.8 0.2 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KKK22602.1 - 5.7e-44 148.7 1.7 1.2e-43 147.6 1.0 1.9 2 0 0 2 2 2 1 Thiolase, C-terminal domain Polysacc_deac_2 PF04748.13 KKK22602.1 - 0.025 13.7 0.1 0.098 11.8 0.0 1.9 2 0 0 2 2 2 0 Divergent polysaccharide deacetylase ketoacyl-synt PF00109.26 KKK22602.1 - 0.031 13.8 0.7 0.12 12.0 0.3 2.0 2 0 0 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain Ribosomal_L50 PF10501.9 KKK22603.1 - 1.3e-24 86.5 0.2 2.4e-24 85.6 0.2 1.4 1 0 0 1 1 1 1 Ribosomal subunit 39S Rtf2 PF04641.12 KKK22604.1 - 1.4e-70 237.7 3.1 2.4e-70 236.9 3.1 1.3 1 0 0 1 1 1 1 Rtf2 RING-finger zf-Nse PF11789.8 KKK22604.1 - 2.7e-07 30.3 0.5 0.0043 16.8 0.2 2.3 2 0 0 2 2 2 2 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 KKK22604.1 - 0.00065 19.7 0.1 0.0025 17.8 0.0 2.0 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 KKK22604.1 - 0.0018 18.2 0.1 0.0018 18.2 0.1 1.8 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KKK22604.1 - 0.011 15.6 0.1 0.025 14.5 0.1 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-NOSIP PF15906.5 KKK22604.1 - 0.025 14.7 0.0 0.066 13.3 0.0 1.7 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein zf-RING_2 PF13639.6 KKK22604.1 - 0.049 14.0 0.1 0.13 12.6 0.1 1.8 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_2 PF13923.6 KKK22604.1 - 0.12 12.3 0.3 0.12 12.3 0.3 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) PRKCSH-like PF12999.7 KKK22605.1 - 1.7e-44 151.7 17.3 1.8e-27 96.3 1.2 3.9 4 0 0 4 4 4 2 Glucosidase II beta subunit-like PRKCSH_1 PF13015.6 KKK22605.1 - 2.7e-32 111.6 1.9 1.4e-31 109.2 0.2 2.4 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.13 KKK22605.1 - 2.7e-10 41.1 0.1 7.8e-10 39.6 0.1 1.9 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein ATG27 PF09451.10 KKK22605.1 - 0.039 13.8 0.0 0.075 12.9 0.0 1.4 1 0 0 1 1 1 0 Autophagy-related protein 27 Mod_r PF07200.13 KKK22605.1 - 0.049 13.7 5.6 0.31 11.2 0.6 2.9 2 1 1 3 3 3 0 Modifier of rudimentary (Mod(r)) protein Fib_alpha PF08702.10 KKK22605.1 - 0.05 13.8 4.3 2.1 8.5 0.0 3.1 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family RNase_H2-Ydr279 PF09468.10 KKK22605.1 - 0.056 13.6 0.6 7.5 6.7 0.1 3.0 1 1 1 2 2 2 0 Ydr279p protein family (RNase H2 complex component) wHTH domain Glutaredoxin2_C PF04399.13 KKK22605.1 - 0.14 12.0 0.8 1.5 8.6 0.0 2.4 2 1 1 3 3 3 0 Glutaredoxin 2, C terminal domain Ldl_recept_a PF00057.18 KKK22605.1 - 0.27 11.5 7.5 0.28 11.4 1.0 2.8 2 0 0 2 2 2 0 Low-density lipoprotein receptor domain class A CCDC53 PF10152.9 KKK22605.1 - 0.65 10.4 4.8 1.6 9.1 4.8 1.5 1 1 0 1 1 1 0 Subunit CCDC53 of WASH complex Sec2p PF06428.11 KKK22605.1 - 1.8 8.6 12.1 1.7 8.7 0.1 3.2 3 0 0 3 3 3 0 GDP/GTP exchange factor Sec2p HR1 PF02185.16 KKK22605.1 - 2.2 8.5 10.1 5.6 7.2 0.1 3.1 3 0 0 3 3 3 0 Hr1 repeat GrpE PF01025.19 KKK22605.1 - 3.6 7.2 18.6 16 5.1 0.5 3.0 2 1 1 3 3 3 0 GrpE Rx_N PF18052.1 KKK22605.1 - 4.5 7.6 7.4 70 3.8 1.3 3.5 3 1 0 3 3 3 0 Rx N-terminal domain DUF4140 PF13600.6 KKK22605.1 - 7 7.2 15.4 3.8 8.0 0.1 3.5 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) DNA_pol_A_exo1 PF01612.20 KKK22614.1 - 3.5e-41 140.8 0.0 6.1e-41 140.0 0.0 1.4 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.12 KKK22614.1 - 1.3e-29 102.7 1.9 4.5e-29 101.0 1.9 2.0 1 0 0 1 1 1 1 PMC2NT (NUC016) domain HRDC PF00570.23 KKK22614.1 - 6.2e-11 42.1 0.1 2.4e-10 40.2 0.0 2.2 2 0 0 2 2 2 1 HRDC domain UPF0203 PF05254.12 KKK22615.1 - 2.2e-23 82.3 0.7 2.6e-23 82.0 0.7 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) COX17 PF05051.13 KKK22615.1 - 0.00013 22.3 0.5 0.00025 21.3 0.5 1.4 1 1 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) DUF3128 PF11326.8 KKK22615.1 - 0.04 14.3 0.5 0.052 13.9 0.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3128) Prp18 PF02840.15 KKK22647.1 - 8.6e-57 191.2 0.3 8.6e-57 191.2 0.3 2.0 2 1 0 2 2 2 1 Prp18 domain PRP4 PF08799.11 KKK22647.1 - 6.1e-10 38.5 7.4 6.1e-10 38.5 7.4 3.3 3 0 0 3 3 3 1 pre-mRNA processing factor 4 (PRP4) like CREPT PF16566.5 KKK22647.1 - 0.45 10.7 9.9 1.4 9.1 9.9 1.8 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour TFIIA PF03153.13 KKK22647.1 - 0.75 9.7 11.5 1.5 8.8 11.5 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SOBP PF15279.6 KKK22647.1 - 2.6 8.6 3.9 3.5 8.2 3.9 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein V_ATPase_I PF01496.19 KKK22647.1 - 4.6 5.0 10.2 9.3 4.0 10.2 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CDC27 PF09507.10 KKK22647.1 - 5.8 6.2 25.9 8.7 5.6 25.9 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Pyr_redox_3 PF13738.6 KKK22648.1 - 0.00019 20.8 0.0 0.0015 17.8 0.0 2.2 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NDUF_B4 PF07225.12 KKK22649.1 - 5.6e-06 26.3 0.0 6.3e-06 26.1 0.0 1.0 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) BCCT PF02028.17 KKK22649.1 - 0.054 11.9 0.1 0.057 11.8 0.1 1.0 1 0 0 1 1 1 0 BCCT, betaine/carnitine/choline family transporter MitoNEET_N PF10660.9 KKK22649.1 - 0.099 12.7 0.2 0.13 12.3 0.2 1.2 1 0 0 1 1 1 0 Iron-containing outer mitochondrial membrane protein N-terminus SAP18 PF06487.12 KKK22650.1 - 2.3e-51 173.7 0.0 2.8e-51 173.4 0.0 1.1 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) 2-Hacid_dh_C PF02826.19 KKK22651.1 - 2.6e-53 180.0 0.0 3.4e-53 179.6 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KKK22651.1 - 1.7e-29 102.1 0.0 2.1e-29 101.9 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AdoHcyase_NAD PF00670.21 KKK22651.1 - 0.059 13.4 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain AlaDh_PNT_C PF01262.21 KKK22651.1 - 0.2 10.9 0.0 4.8 6.4 0.0 2.3 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain GST_N PF02798.20 KKK22652.1 - 1.8e-13 50.6 0.1 4.4e-13 49.4 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KKK22652.1 - 2.8e-10 40.5 0.0 5.7e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KKK22652.1 - 1.8e-09 37.8 0.0 3.3e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KKK22652.1 - 2.2e-08 34.2 0.0 4e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KKK22652.1 - 1.3e-05 25.1 0.0 3e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 KKK22652.1 - 0.0001 22.9 0.1 0.00027 21.5 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KKK22652.1 - 0.0002 21.5 0.0 0.00034 20.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Arf PF00025.21 KKK22653.1 - 2.1e-40 138.0 0.0 2.4e-26 92.3 0.0 2.3 2 1 0 2 2 2 2 ADP-ribosylation factor family G-alpha PF00503.20 KKK22653.1 - 6.4e-14 51.9 0.0 1.4e-07 31.0 0.0 2.3 2 1 0 2 2 2 2 G-protein alpha subunit Roc PF08477.13 KKK22653.1 - 1.6e-09 38.0 0.0 5.6e-09 36.2 0.0 1.9 2 1 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 KKK22653.1 - 4.9e-07 29.3 0.0 1e-06 28.3 0.0 1.7 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.22 KKK22653.1 - 2.6e-06 27.2 0.0 0.0064 16.1 0.0 2.8 2 1 0 2 2 2 2 Ras family SRPRB PF09439.10 KKK22653.1 - 6.5e-06 25.7 0.0 0.0001 21.8 0.0 2.1 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KKK22653.1 - 4e-05 23.7 0.0 9.7e-05 22.4 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KKK22653.1 - 0.0015 18.1 0.0 0.043 13.3 0.0 2.4 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain TniB PF05621.11 KKK22653.1 - 0.16 11.4 0.0 0.26 10.7 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein FeoB_N PF02421.18 KKK22653.1 - 0.2 11.2 0.0 0.45 10.0 0.0 1.7 1 1 0 1 1 1 0 Ferrous iron transport protein B Glycos_transf_1 PF00534.20 KKK22654.1 - 4.8e-23 81.6 0.0 7.1e-23 81.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KKK22654.1 - 4.7e-21 75.6 0.0 7.1e-21 75.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KKK22654.1 - 1.3e-09 38.3 0.0 2.2e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 PIGA PF08288.12 KKK22654.1 - 1.7e-05 25.3 1.5 9.3e-05 22.9 0.3 2.4 2 0 0 2 2 2 1 PIGA (GPI anchor biosynthesis) Glyco_trans_1_2 PF13524.6 KKK22654.1 - 0.0074 16.7 0.0 0.016 15.6 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Fungal_trans_2 PF11951.8 KKK22674.1 - 1.1e-72 245.0 0.1 1.3e-72 244.8 0.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK22674.1 - 7.9e-08 32.3 8.3 1.6e-07 31.4 8.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain F-actin_cap_A PF01267.17 KKK22675.1 - 2.5e-85 286.2 0.0 3.3e-85 285.7 0.0 1.2 1 0 0 1 1 1 1 F-actin capping protein alpha subunit PEX11 PF05648.14 KKK22675.1 - 4.6e-31 108.0 0.0 1.4e-30 106.4 0.0 1.9 1 1 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) DUF3987 PF13148.6 KKK22675.1 - 0.068 12.2 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) CCP_MauG PF03150.14 KKK22675.1 - 0.11 13.2 0.0 0.27 11.9 0.0 1.6 1 0 0 1 1 1 0 Di-haem cytochrome c peroxidase DUF512 PF04459.12 KKK22675.1 - 0.13 11.5 0.0 8.6 5.6 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF512) Zn_clus PF00172.18 KKK22676.1 - 3.9e-07 30.1 10.8 9e-07 28.9 10.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KKK22676.1 - 0.00018 20.6 0.2 0.00037 19.6 0.2 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Med7 PF05983.11 KKK22677.1 - 9.5e-63 211.7 2.0 1.2e-62 211.5 2.0 1.1 1 0 0 1 1 1 1 MED7 protein MerR-DNA-bind PF09278.11 KKK22677.1 - 0.067 13.7 0.9 0.16 12.5 0.9 1.7 1 0 0 1 1 1 0 MerR, DNA binding APG6_N PF17675.1 KKK22677.1 - 2 8.9 6.5 0.19 12.3 2.2 1.5 2 0 0 2 2 2 0 Apg6 coiled-coil region PAP2 PF01569.21 KKK22678.1 - 4.1e-28 97.8 0.8 4.1e-28 97.8 0.8 2.1 2 0 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 KKK22678.1 - 0.003 17.3 7.6 0.018 14.8 7.5 2.1 1 1 0 1 1 1 1 PAP2 superfamily SLATT_fungal PF18142.1 KKK22678.1 - 0.12 12.3 0.4 1 9.3 0.4 2.1 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain Colicin_V PF02674.16 KKK22678.1 - 0.25 11.3 7.4 14 5.7 3.4 3.4 3 1 0 3 3 3 0 Colicin V production protein p450 PF00067.22 KKK22679.1 - 1.9e-66 224.7 0.0 2.4e-66 224.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ADPRTs_Tse2 PF18648.1 KKK22680.1 - 0.00097 19.2 0.2 0.0016 18.5 0.0 1.7 2 0 0 2 2 2 1 Tse2 ADP-ribosyltransferase toxins T5orf172 PF10544.9 KKK22681.1 - 7.7e-14 52.1 0.0 1.7e-13 51.0 0.0 1.6 1 0 0 1 1 1 1 T5orf172 domain MUG113 PF13455.6 KKK22681.1 - 0.0019 18.8 0.2 0.0091 16.6 0.0 2.2 3 0 0 3 3 3 1 Meiotically up-regulated gene 113 2-Hacid_dh_C PF02826.19 KKK22683.1 - 1.5e-12 47.3 0.1 8.3e-12 44.8 0.1 2.2 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KKK22683.1 - 7.5e-07 28.9 0.0 1.1e-06 28.4 0.0 1.4 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain SET PF00856.28 KKK22684.1 - 0.086 13.2 0.0 0.1 13.0 0.0 1.2 1 0 0 1 1 1 0 SET domain Tannase PF07519.11 KKK22685.1 - 2.4e-83 280.6 0.0 2.8e-83 280.4 0.0 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Peptidase_S9 PF00326.21 KKK22685.1 - 0.0037 16.8 0.1 1.1 8.7 0.2 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 KKK22685.1 - 0.025 14.2 0.0 0.063 12.9 0.0 1.6 1 0 0 1 1 1 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KKK22685.1 - 0.12 11.6 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Ras PF00071.22 KKK22686.1 - 3.9e-31 107.8 0.2 5e-31 107.5 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KKK22686.1 - 1.4e-23 83.4 0.1 2.2e-23 82.7 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKK22686.1 - 1.2e-06 28.1 0.1 1.7e-06 27.6 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KKK22686.1 - 0.00022 20.6 0.2 0.0003 20.2 0.2 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DLIC PF05783.11 KKK22686.1 - 0.014 14.2 0.1 1.9 7.3 0.0 2.1 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) NPC1_N PF16414.5 KKK22687.1 - 1.6e-85 286.5 4.9 2.3e-85 286.0 4.9 1.2 1 0 0 1 1 1 1 Niemann-Pick C1 N terminus Patched PF02460.18 KKK22687.1 - 3.8e-77 260.1 15.7 1.6e-76 258.1 15.7 1.7 1 1 0 1 1 1 1 Patched family Sterol-sensing PF12349.8 KKK22687.1 - 2.7e-52 176.7 7.4 2.7e-52 176.7 7.4 3.1 3 1 0 3 3 3 1 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.15 KKK22687.1 - 1.6e-06 27.3 9.8 1.6e-06 27.3 9.8 3.4 3 1 0 3 3 3 2 MMPL family REV1_C PF16727.5 KKK22687.1 - 0.02 15.3 0.0 0.048 14.1 0.0 1.6 1 0 0 1 1 1 0 DNA repair protein REV1 C-terminal domain Folate_rec PF03024.14 KKK22687.1 - 0.02 14.8 3.0 0.04 13.8 3.0 1.4 1 0 0 1 1 1 0 Folate receptor family ADH_N PF08240.12 KKK22688.1 - 7.9e-28 96.5 1.2 1.2e-27 95.9 0.3 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KKK22688.1 - 8.2e-20 71.1 0.0 1.5e-19 70.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KKK22688.1 - 5.4e-06 27.5 0.0 1.2e-05 26.3 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KKK22688.1 - 6e-05 22.6 0.0 0.00012 21.6 0.0 1.6 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 KKK22688.1 - 0.0022 17.3 0.0 0.0037 16.6 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ADH_N_assoc PF13823.6 KKK22688.1 - 0.072 13.0 0.1 0.12 12.3 0.1 1.4 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-associated Pkinase PF00069.25 KKK22689.1 - 3e-25 89.1 0.0 4.3e-25 88.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK22689.1 - 4.8e-05 22.8 0.0 8.6e-05 21.9 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KKK22689.1 - 0.21 10.3 0.0 0.45 9.2 0.0 1.3 1 1 0 1 1 1 0 Fungal protein kinase Epimerase PF01370.21 KKK22691.1 - 4.1e-16 59.2 0.0 6.6e-16 58.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KKK22691.1 - 2.7e-10 40.2 0.1 5.6e-10 39.2 0.0 1.6 2 0 0 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.6 KKK22691.1 - 2.1e-08 34.3 0.2 3.2e-08 33.7 0.2 1.4 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 KKK22691.1 - 2.3e-08 33.8 0.0 5.1e-05 22.8 0.0 2.4 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KKK22691.1 - 4.2e-08 32.5 0.0 4.3e-07 29.2 0.0 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 KKK22691.1 - 7.2e-05 22.0 0.1 9.2e-05 21.7 0.1 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 KKK22691.1 - 0.00059 19.1 0.6 0.47 9.6 0.4 2.2 1 1 1 2 2 2 2 Male sterility protein Sacchrp_dh_NADP PF03435.18 KKK22691.1 - 0.0028 17.9 0.0 0.0046 17.2 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain adh_short PF00106.25 KKK22691.1 - 0.041 13.3 0.0 0.078 12.4 0.0 1.5 1 0 0 1 1 1 0 short chain dehydrogenase HEAT_EZ PF13513.6 KKK22692.1 - 2.7e-21 75.7 5.6 3.9e-07 30.4 0.0 9.2 9 0 0 9 9 8 3 HEAT-like repeat HEAT_2 PF13646.6 KKK22692.1 - 6.8e-19 68.1 5.1 0.00099 19.5 0.0 7.6 5 2 2 7 7 7 5 HEAT repeats HEAT PF02985.22 KKK22692.1 - 3.1e-18 64.3 1.2 0.00052 20.0 0.1 8.7 9 0 0 9 9 7 2 HEAT repeat Cnd1 PF12717.7 KKK22692.1 - 1.9e-14 54.0 0.1 8.5e-06 25.9 0.0 4.3 4 0 0 4 4 4 3 non-SMC mitotic condensation complex subunit 1 IFRD PF05004.13 KKK22692.1 - 2.5e-10 40.0 0.0 0.00034 19.8 0.0 4.0 3 1 1 4 4 4 3 Interferon-related developmental regulator (IFRD) MMS19_C PF12460.8 KKK22692.1 - 2.6e-09 36.7 1.2 0.0002 20.6 0.0 3.2 3 0 0 3 3 3 2 RNAPII transcription regulator C-terminal IBN_N PF03810.19 KKK22692.1 - 4.3e-09 36.1 0.3 2e-07 30.8 0.0 3.1 3 0 0 3 3 2 1 Importin-beta N-terminal domain Vac14_Fab1_bd PF12755.7 KKK22692.1 - 4.9e-09 36.7 0.0 0.55 10.9 0.0 5.9 5 1 1 6 6 5 2 Vacuolar 14 Fab1-binding region Arm PF00514.23 KKK22692.1 - 1.1e-06 28.4 0.0 3.4 7.8 0.0 5.4 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat CLASP_N PF12348.8 KKK22692.1 - 2.1e-06 27.5 0.0 0.069 12.7 0.0 3.9 4 0 0 4 4 4 2 CLASP N terminal RIX1 PF08167.12 KKK22692.1 - 1.1e-05 25.2 0.0 0.024 14.4 0.0 2.7 2 0 0 2 2 2 2 rRNA processing/ribosome biogenesis UME PF08064.13 KKK22692.1 - 0.00012 22.0 0.0 1.3 9.0 0.0 5.0 3 2 2 5 5 5 1 UME (NUC010) domain RTP1_C1 PF10363.9 KKK22692.1 - 0.00013 22.1 1.8 4.7 7.4 0.0 5.0 4 1 0 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 Adaptin_N PF01602.20 KKK22692.1 - 0.00014 20.6 0.2 0.25 9.8 0.0 3.2 3 0 0 3 3 3 2 Adaptin N terminal region DRIM PF07539.12 KKK22692.1 - 0.00044 18.7 1.4 1.2 7.3 0.1 3.7 3 1 0 3 3 3 2 Down-regulated in metastasis ParcG PF10274.9 KKK22692.1 - 0.00086 19.5 0.5 0.051 13.7 0.1 3.2 3 1 1 4 4 4 1 Parkin co-regulated protein Sec7_N PF12783.7 KKK22692.1 - 0.0013 18.6 0.0 0.0098 15.8 0.0 2.5 2 1 0 2 2 1 1 Guanine nucleotide exchange factor in Golgi transport N-terminal V-ATPase_H_C PF11698.8 KKK22692.1 - 0.005 16.9 0.1 2.3 8.4 0.0 4.2 4 0 0 4 4 4 1 V-ATPase subunit H DUF577 PF04510.12 KKK22692.1 - 0.0055 16.6 0.0 0.051 13.5 0.0 2.6 3 0 0 3 3 3 1 Family of unknown function (DUF577) UNC45-central PF11701.8 KKK22692.1 - 0.013 15.5 0.2 0.26 11.3 0.2 3.2 3 1 1 4 4 3 0 Myosin-binding striated muscle assembly central NopRA1 PF16201.5 KKK22692.1 - 0.017 14.8 0.4 7.9 6.0 0.0 3.6 3 1 1 4 4 4 0 Nucleolar pre-ribosomal-associated protein 1 V-ATPase_H_N PF03224.14 KKK22692.1 - 0.022 14.1 0.7 4.6 6.4 0.0 3.7 3 1 0 3 3 3 0 V-ATPase subunit H Cohesin_HEAT PF12765.7 KKK22692.1 - 0.056 13.8 0.0 6.6 7.1 0.0 3.0 3 0 0 3 3 2 0 HEAT repeat associated with sister chromatid cohesion DUF4042 PF13251.6 KKK22692.1 - 0.12 12.1 0.1 2.1 8.0 0.0 3.1 3 1 0 3 3 3 0 Domain of unknown function (DUF4042) Tti2 PF10521.9 KKK22692.1 - 0.15 11.6 0.1 3.4 7.1 0.0 3.1 3 1 1 4 4 3 0 Tti2 family SET PF00856.28 KKK22708.1 - 7.3e-17 62.3 0.3 6e-16 59.3 0.1 2.5 2 1 0 2 2 2 1 SET domain Pre-SET PF05033.16 KKK22708.1 - 4.2e-12 46.7 3.8 4.2e-12 46.7 3.8 2.6 2 1 0 2 2 2 1 Pre-SET motif AWS PF17907.1 KKK22708.1 - 0.005 16.9 1.4 0.005 16.9 1.4 2.8 3 0 0 3 3 3 1 AWS domain CSRNP_N PF16019.5 KKK22708.1 - 1.2 9.0 7.0 0.42 10.5 1.5 2.4 2 0 0 2 2 2 0 Cysteine/serine-rich nuclear protein N-terminus SUIM_assoc PF16619.5 KKK22708.1 - 1.2 9.2 9.4 0.38 10.9 6.0 2.0 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 zf-C2H2 PF00096.26 KKK22709.1 - 2.8e-29 99.9 63.0 5.1e-05 23.5 0.4 11.3 10 2 1 11 11 11 10 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KKK22709.1 - 3e-17 61.8 61.4 0.029 15.2 0.3 11.4 11 0 0 11 11 11 7 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KKK22709.1 - 1.5e-12 47.3 54.5 0.00073 19.8 0.5 10.9 11 0 0 11 11 11 6 Zinc-finger double domain FOXP-CC PF16159.5 KKK22709.1 - 8.7e-06 26.3 32.9 0.16 12.6 0.1 9.1 6 2 3 9 9 9 3 FOXP coiled-coil domain zf-C2H2_jaz PF12171.8 KKK22709.1 - 4.2e-05 23.7 16.3 15 6.0 0.1 8.6 10 0 0 10 10 10 1 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 KKK22709.1 - 0.00046 20.4 24.4 0.38 11.1 1.2 5.3 3 2 3 6 6 6 4 C2H2-type zinc ribbon zf-C2H2_3rep PF18868.1 KKK22709.1 - 0.0029 18.3 19.5 0.89 10.2 0.1 4.8 1 1 1 4 4 4 3 Zinc finger C2H2-type, 3 repeats zf-C2H2_11 PF16622.5 KKK22709.1 - 0.25 11.1 14.5 5.9 6.8 1.3 5.1 5 0 0 5 5 5 0 zinc-finger C2H2-type GAGA PF09237.11 KKK22709.1 - 0.38 10.6 4.8 0.36 10.7 1.7 2.6 2 0 0 2 2 2 0 GAGA factor zf_Hakai PF18408.1 KKK22709.1 - 4.5 7.1 19.0 15 5.4 0.1 6.0 5 0 0 5 5 5 0 C2H2 Hakai zinc finger domain RNA_pol_Rpb6 PF01192.22 KKK22710.1 - 2.5e-17 62.5 0.3 4.7e-17 61.7 0.1 1.6 2 0 0 2 2 2 1 RNA polymerase Rpb6 MFS_1 PF07690.16 KKK22711.1 - 2.1e-21 76.3 51.9 2.6e-19 69.4 40.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily G-gamma PF00631.22 KKK22712.1 - 1.9e-24 85.4 0.0 2.2e-24 85.2 0.0 1.1 1 0 0 1 1 1 1 GGL domain DUF3220 PF11516.8 KKK22712.1 - 0.071 13.3 0.0 0.097 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3120) PCI PF01399.27 KKK22713.1 - 1.8e-10 41.3 3.4 6.6e-10 39.4 0.0 3.4 3 1 0 3 3 3 1 PCI domain Vps4_C PF09336.10 KKK22713.1 - 0.069 13.2 0.4 5.7 7.0 0.1 2.7 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain Acetyltransf_1 PF00583.25 KKK22715.1 - 2.5e-08 34.2 0.0 3.6e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KKK22715.1 - 3.8e-07 30.1 0.0 6.3e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KKK22715.1 - 1.8e-05 25.1 0.0 2.5e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KKK22715.1 - 3.1e-05 23.9 0.0 5.3e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 KKK22715.1 - 0.035 14.2 0.1 0.078 13.1 0.1 1.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Glyco_hydro_6 PF01341.17 KKK22716.1 - 7.4e-106 354.3 0.2 9e-106 354.0 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 Aldo_ket_red PF00248.21 KKK22718.1 - 1.5e-40 139.2 0.0 9.5e-39 133.3 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Inhibitor_I78 PF11720.8 KKK22719.1 - 2.1e-09 37.3 0.0 2.8e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase inhibitor I78 family potato_inhibit PF00280.18 KKK22719.1 - 6.4e-05 23.6 0.1 8.6e-05 23.1 0.1 1.3 1 1 0 1 1 1 1 Potato inhibitor I family Nefa_Nip30_N PF10187.9 KKK22720.1 - 3.4e-32 110.9 13.3 3.4e-32 110.9 13.3 2.4 2 1 1 3 3 3 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 Sugar_tr PF00083.24 KKK22721.1 - 3.7e-102 342.5 18.4 4.2e-102 342.3 18.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKK22721.1 - 1.7e-28 99.5 28.3 2.8e-19 69.3 11.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily VEGFR-2_TMD PF17988.1 KKK22721.1 - 0.53 9.8 2.3 1.8 8.0 2.3 2.0 1 0 0 1 1 1 0 VEGFR-2 Transmembrane domain Alpha-L-AF_C PF06964.12 KKK22722.1 - 2.5e-30 105.8 0.1 3.6e-30 105.3 0.1 1.2 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminal domain Glyco_hydro_44 PF12891.7 KKK22722.1 - 0.061 13.3 1.0 0.2 11.6 1.0 1.8 1 1 0 1 1 1 0 Glycoside hydrolase family 44 TatD_DNase PF01026.21 KKK22723.1 - 1e-47 162.7 0.0 1.3e-47 162.3 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase Fe_hyd_lg_C PF02906.14 KKK22724.1 - 7.4e-53 179.7 0.0 1.5e-52 178.7 0.0 1.4 1 1 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain Cu-oxidase_2 PF07731.14 KKK22725.1 - 4.6e-49 165.7 10.0 1.4e-42 144.7 2.1 3.6 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 KKK22725.1 - 1.7e-40 137.7 6.3 5.8e-38 129.6 1.5 3.4 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 KKK22725.1 - 6.7e-40 136.8 3.9 9e-34 116.9 0.4 3.6 3 0 0 3 3 3 3 Multicopper oxidase Cupredoxin_1 PF13473.6 KKK22725.1 - 0.005 16.9 0.0 6.7 6.9 0.0 3.7 4 0 0 4 4 4 1 Cupredoxin-like domain Self-incomp_S1 PF05938.11 KKK22725.1 - 0.031 14.8 0.1 8.4 7.0 0.1 2.4 2 0 0 2 2 2 0 Plant self-incompatibility protein S1 FTR1 PF03239.14 KKK22726.1 - 1.9e-83 280.2 8.4 2.4e-83 279.8 8.4 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family Cation_efflux PF01545.21 KKK22726.1 - 0.012 15.4 2.9 0.012 15.4 2.9 1.9 2 1 0 2 2 2 0 Cation efflux family GPDPase_memb PF10110.9 KKK22726.1 - 0.55 9.0 7.5 0.92 8.2 1.0 2.5 2 0 0 2 2 2 0 Membrane domain of glycerophosphoryl diester phosphodiesterase DUF924 PF06041.11 KKK22727.1 - 1.7e-48 165.2 6.2 9.9e-48 162.7 6.2 2.0 1 1 0 1 1 1 1 Bacterial protein of unknown function (DUF924) Adeno_terminal PF02459.15 KKK22727.1 - 0.042 12.2 0.6 0.054 11.9 0.6 1.1 1 0 0 1 1 1 0 Adenoviral DNA terminal protein RNA_pol_3_Rpc31 PF11705.8 KKK22727.1 - 0.16 12.2 6.4 0.3 11.3 6.4 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 DUF3435 PF11917.8 KKK22728.1 - 3.9e-128 427.9 0.1 6.8e-106 354.7 0.0 2.4 1 1 1 2 2 2 2 Protein of unknown function (DUF3435) zf-C2H2_11 PF16622.5 KKK22728.1 - 0.021 14.5 1.6 0.068 12.9 1.6 1.8 1 0 0 1 1 1 0 zinc-finger C2H2-type zf-C2H2_4 PF13894.6 KKK22728.1 - 0.14 13.1 3.8 0.5 11.4 3.8 2.0 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2 PF00096.26 KKK22728.1 - 0.61 10.7 4.1 1.6 9.3 4.1 1.8 1 0 0 1 1 1 0 Zinc finger, C2H2 type DUF1295 PF06966.12 KKK22729.1 - 6.4e-10 39.0 0.0 9.7e-10 38.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.16 KKK22729.1 - 5.6e-05 23.2 0.0 0.00012 22.1 0.0 1.5 1 1 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DNA_RNApol_7kD PF03604.13 KKK22730.1 - 1.1e-17 63.4 6.3 1.4e-17 63.1 6.3 1.1 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit DUF2197 PF09963.9 KKK22730.1 - 0.00032 20.9 0.9 0.041 14.1 0.0 2.1 1 1 1 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2197) zf_UBZ PF18439.1 KKK22730.1 - 0.0019 17.7 0.8 1.4 8.6 0.2 2.1 2 0 0 2 2 2 2 Ubiquitin-Binding Zinc Finger DZR PF12773.7 KKK22730.1 - 0.0044 17.0 0.3 0.0063 16.5 0.3 1.2 1 0 0 1 1 1 1 Double zinc ribbon zinc-ribbon_6 PF10005.9 KKK22730.1 - 0.0063 17.2 0.4 0.0077 16.9 0.4 1.1 1 0 0 1 1 1 1 zinc-ribbon domain zinc-ribbons_6 PF07191.12 KKK22730.1 - 0.0082 16.1 0.7 0.011 15.7 0.7 1.2 1 0 0 1 1 1 1 zinc-ribbons HypA PF01155.19 KKK22730.1 - 0.012 15.6 0.3 0.015 15.3 0.3 1.1 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn-ribbon_8 PF09723.10 KKK22730.1 - 0.013 15.6 1.2 0.027 14.6 1.2 1.6 1 1 0 1 1 1 0 Zinc ribbon domain DUF2318 PF10080.9 KKK22730.1 - 0.023 14.8 0.2 0.028 14.5 0.2 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) TFIIS_C PF01096.18 KKK22730.1 - 0.026 14.4 0.3 4 7.4 0.2 2.3 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) PhnA_Zn_Ribbon PF08274.12 KKK22730.1 - 0.027 14.4 0.2 0.04 13.9 0.2 1.2 1 0 0 1 1 1 0 PhnA Zinc-Ribbon zf-ISL3 PF14690.6 KKK22730.1 - 0.35 11.6 0.6 0.35 11.6 0.6 2.0 1 1 1 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Zn_ribbon_recom PF13408.6 KKK22730.1 - 0.39 11.3 5.7 2.5 8.7 1.1 2.1 1 1 1 2 2 2 0 Recombinase zinc beta ribbon domain Glycos_transf_3 PF00591.21 KKK22731.1 - 1.1e-53 182.5 0.0 2e-52 178.3 0.0 2.2 1 1 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.17 KKK22731.1 - 2.1e-08 33.9 0.3 4.9e-08 32.7 0.3 1.7 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain DUF3349 PF11829.8 KKK22731.1 - 0.052 14.3 0.2 20 6.0 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3349) Ribosomal_L10 PF00466.20 KKK22732.1 - 0.025 14.7 0.0 0.72 10.0 0.0 2.7 1 1 0 1 1 1 0 Ribosomal protein L10 PI-PLC-X PF00388.19 KKK22733.1 - 2.2e-10 40.3 0.0 3.5e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain Cut8 PF08559.10 KKK22734.1 - 3.8e-79 265.7 0.0 4.7e-79 265.4 0.0 1.0 1 0 0 1 1 1 1 Cut8, nuclear proteasome tether protein PHD PF00628.29 KKK22735.1 - 3.1e-08 33.4 9.8 3.1e-08 33.4 9.8 1.9 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.6 KKK22735.1 - 0.12 11.9 9.7 0.03 13.9 5.6 2.0 2 0 0 2 2 2 0 PHD-finger C1_2 PF03107.16 KKK22735.1 - 7 7.1 6.8 0.97 9.8 2.0 1.9 2 0 0 2 2 2 0 C1 domain zf-RING_9 PF13901.6 KKK22735.1 - 7.4 6.5 9.1 12 5.8 9.1 1.3 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon DIOX_N PF14226.6 KKK22737.1 - 9.4e-28 97.3 0.0 1.5e-27 96.7 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KKK22737.1 - 2.7e-17 63.1 0.0 4.8e-17 62.3 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Rcd1 PF04078.13 KKK22738.1 - 1.7e-122 407.7 2.7 2.1e-122 407.4 2.7 1.1 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like ARS2 PF04959.13 KKK22738.1 - 3.2 8.1 8.0 4.8 7.5 8.0 1.2 1 0 0 1 1 1 0 Arsenite-resistance protein 2 TFIIA PF03153.13 KKK22738.1 - 5 7.0 16.9 6.5 6.6 16.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Med15 PF09606.10 KKK22738.1 - 8.1 5.0 20.9 9.6 4.7 20.9 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal TMEM51 PF15345.6 KKK22739.1 - 0.031 14.1 0.2 0.18 11.7 0.0 2.2 2 1 0 2 2 2 0 Transmembrane protein 51 Gram_pos_anchor PF00746.21 KKK22739.1 - 0.7 9.9 0.0 0.7 9.9 0.0 2.7 3 0 0 3 3 3 0 LPXTG cell wall anchor motif NPAT_C PF15712.5 KKK22739.1 - 4.9 5.7 7.7 6.2 5.3 7.7 1.2 1 0 0 1 1 1 0 NPAT C terminus Prefoldin_2 PF01920.20 KKK22740.1 - 3e-20 72.2 3.9 3.7e-20 71.9 3.9 1.2 1 0 0 1 1 1 1 Prefoldin subunit T6PP_N PF18572.1 KKK22740.1 - 0.0031 17.3 3.7 0.011 15.5 3.7 1.8 1 1 0 1 1 1 1 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain Rootletin PF15035.6 KKK22740.1 - 0.027 14.5 1.2 0.26 11.3 0.1 2.0 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion DUF724 PF05266.14 KKK22740.1 - 0.15 11.8 2.1 1.3 8.8 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF724) FlaC_arch PF05377.11 KKK22740.1 - 0.19 12.2 4.2 0.56 10.6 0.2 2.5 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Tropomyosin_1 PF12718.7 KKK22740.1 - 0.39 10.9 4.7 0.94 9.6 0.8 2.1 2 0 0 2 2 2 0 Tropomyosin like SlyX PF04102.12 KKK22740.1 - 1.2 9.8 5.2 7.8 7.2 1.6 2.2 2 0 0 2 2 2 0 SlyX YabA PF06156.13 KKK22740.1 - 3.2 8.5 6.1 71 4.1 6.1 2.1 1 1 0 1 1 1 0 Initiation control protein YabA ApbA PF02558.16 KKK22748.1 - 5.4e-26 91.1 0.0 8e-26 90.5 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 KKK22748.1 - 8.1e-19 68.1 0.0 1.3e-18 67.3 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal DASH_Hsk3 PF08227.11 KKK22749.1 - 2e-21 76.1 0.8 3.8e-21 75.2 0.8 1.5 1 0 0 1 1 1 1 DASH complex subunit Hsk3 like Phostensin PF13914.6 KKK22749.1 - 0.0066 17.1 0.0 0.0097 16.5 0.0 1.2 1 0 0 1 1 1 1 Phostensin PP1-binding and SH3-binding region BBS2_C PF14782.6 KKK22749.1 - 0.014 14.2 0.0 0.015 14.0 0.0 1.2 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, C-terminal Chorion_2 PF03964.15 KKK22749.1 - 0.19 12.6 6.4 0.35 11.7 6.4 1.4 1 0 0 1 1 1 0 Chorion family 2 Macoilin PF09726.9 KKK22749.1 - 0.23 9.9 4.1 0.22 10.0 4.1 1.1 1 0 0 1 1 1 0 Macoilin family His_Phos_1 PF00300.22 KKK22750.1 - 7.9e-35 120.3 1.9 1.7e-32 112.7 1.9 2.8 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AdoMet_MTase PF07757.13 KKK22751.1 - 5.4e-34 116.9 0.1 1.2e-32 112.5 0.1 2.3 1 1 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase Protoglobin PF11563.8 KKK22756.1 - 7.1e-58 195.0 0.4 8.9e-58 194.7 0.4 1.1 1 0 0 1 1 1 1 Protoglobin Sel1 PF08238.12 KKK22772.1 - 2.3e-15 56.7 21.2 4e-07 30.5 0.0 6.7 7 0 0 7 7 7 4 Sel1 repeat TPR_1 PF00515.28 KKK22772.1 - 0.00013 21.6 0.1 0.0009 19.0 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 KKK22772.1 - 0.0029 17.6 1.2 0.025 14.7 0.0 3.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 KKK22772.1 - 0.015 16.0 0.2 0.13 13.2 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Laminin_I PF06008.14 KKK22773.1 - 0.00097 18.9 4.6 0.0013 18.6 4.6 1.2 1 0 0 1 1 1 1 Laminin Domain I Vps51 PF08700.11 KKK22773.1 - 0.00098 19.2 0.6 0.6 10.2 0.2 2.3 2 0 0 2 2 2 2 Vps51/Vps67 EzrA PF06160.12 KKK22773.1 - 0.0015 16.8 1.2 0.0018 16.5 1.2 1.2 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA DivIC PF04977.15 KKK22773.1 - 0.0026 17.5 5.6 0.0066 16.2 1.0 2.4 2 0 0 2 2 2 1 Septum formation initiator TBPIP PF07106.13 KKK22773.1 - 0.0066 16.4 0.0 0.013 15.4 0.0 1.5 1 0 0 1 1 1 1 TBPIP/Hop2 winged helix domain DUF5082 PF16888.5 KKK22773.1 - 0.028 14.7 1.0 0.068 13.4 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) Miff PF05644.11 KKK22773.1 - 0.031 13.9 1.3 0.037 13.7 0.8 1.4 1 1 0 1 1 1 0 Mitochondrial and peroxisomal fission factor Mff DUF3381 PF11861.8 KKK22773.1 - 0.033 14.0 1.5 0.033 14.0 1.5 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) Apt1 PF10351.9 KKK22773.1 - 0.034 13.0 2.1 0.042 12.7 2.1 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain TMCO5 PF14992.6 KKK22773.1 - 0.047 13.3 3.3 0.11 12.1 2.4 1.9 2 0 0 2 2 2 0 TMCO5 family V_ATPase_I PF01496.19 KKK22773.1 - 0.099 10.5 0.6 0.11 10.4 0.6 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Seryl_tRNA_N PF02403.22 KKK22773.1 - 0.13 12.5 5.3 0.2 11.9 5.3 1.5 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF4140 PF13600.6 KKK22773.1 - 0.14 12.6 9.6 0.081 13.4 3.4 2.7 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) DUF1690 PF07956.11 KKK22773.1 - 0.24 11.8 6.9 0.41 11.1 6.7 1.6 1 1 0 1 1 1 0 Protein of Unknown function (DUF1690) DUF4337 PF14235.6 KKK22773.1 - 0.31 11.1 4.3 6.6 6.8 1.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) FlxA PF14282.6 KKK22773.1 - 0.41 10.7 6.7 1.6 8.8 6.7 2.0 1 1 0 1 1 1 0 FlxA-like protein APG6_N PF17675.1 KKK22773.1 - 0.64 10.5 12.4 2.5 8.6 12.3 2.0 1 1 0 1 1 1 0 Apg6 coiled-coil region SlyX PF04102.12 KKK22773.1 - 0.93 10.2 7.5 0.4 11.3 3.1 2.4 2 1 0 2 2 2 0 SlyX ZapB PF06005.12 KKK22773.1 - 1.5 9.3 10.6 2 8.9 4.4 2.5 1 1 1 2 2 2 0 Cell division protein ZapB OmpH PF03938.14 KKK22773.1 - 1.6 9.1 7.7 2.7 8.3 7.7 1.5 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Uso1_p115_C PF04871.13 KKK22773.1 - 1.8 8.9 13.3 1.3 9.4 6.8 2.1 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region LPP PF04728.13 KKK22773.1 - 2.8 8.4 5.6 14 6.2 0.6 2.5 2 0 0 2 2 2 0 Lipoprotein leucine-zipper PRIMA1 PF16101.5 KKK22774.1 - 0.0076 16.3 3.2 0.016 15.2 3.2 1.5 1 0 0 1 1 1 1 Proline-rich membrane anchor 1 CAP_N PF01213.19 KKK22774.1 - 0.059 12.8 2.4 0.22 11.0 2.6 1.7 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal NeA_P2 PF12312.8 KKK22774.1 - 0.066 12.7 0.4 0.1 12.0 0.4 1.3 1 0 0 1 1 1 0 Nepovirus subgroup A polyprotein RLL PF10036.9 KKK22774.1 - 0.094 12.5 0.1 0.14 12.0 0.1 1.3 1 0 0 1 1 1 0 RNA transcription, translation and transport factor protein DAP3 PF10236.9 KKK22776.1 - 1.3e-109 366.2 0.0 1.7e-109 365.8 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 T2SSE PF00437.20 KKK22776.1 - 0.00043 19.4 0.0 0.00072 18.7 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_16 PF13191.6 KKK22776.1 - 0.013 15.9 0.0 0.024 15.0 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_14 PF13173.6 KKK22776.1 - 0.036 14.1 0.0 0.061 13.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain Snf7 PF03357.21 KKK22778.1 - 5.4e-19 68.4 20.8 5.9e-19 68.3 20.1 1.4 1 1 0 1 1 1 1 Snf7 PspA_IM30 PF04012.12 KKK22778.1 - 0.089 12.4 28.7 0.17 11.5 24.2 2.7 1 1 1 2 2 2 0 PspA/IM30 family PAXX PF15384.6 KKK22778.1 - 0.38 10.4 4.5 0.11 12.1 0.7 2.1 2 1 0 2 2 2 0 PAXX, PAralog of XRCC4 and XLF, also called C9orf142 Cu-oxidase_4 PF02578.15 KKK22778.1 - 0.68 9.5 3.5 5.9 6.4 3.5 2.0 1 1 0 1 1 1 0 Multi-copper polyphenol oxidoreductase laccase PIN_6 PF17146.4 KKK22778.1 - 0.77 10.3 6.5 10 6.7 0.0 3.6 2 1 1 3 3 3 0 PIN domain of ribonuclease MecA PF05389.12 KKK22778.1 - 1.3 8.6 10.9 0.1 12.2 4.9 1.9 1 1 1 2 2 2 0 Negative regulator of genetic competence (MecA) DUF2203 PF09969.9 KKK22778.1 - 1.4 9.6 17.4 0.53 11.0 4.8 2.6 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) DASH_Dad4 PF08650.10 KKK22778.1 - 3.4 7.7 6.1 3.2 7.8 1.8 2.8 2 1 0 2 2 2 0 DASH complex subunit Dad4 DASH_Dad2 PF08654.10 KKK22778.1 - 6.6 7.2 15.1 0.83 10.1 3.7 3.3 1 1 1 2 2 2 0 DASH complex subunit Dad2 TssO PF17561.2 KKK22778.1 - 7.5 6.6 13.5 1.2 9.2 3.1 2.6 1 1 2 3 3 3 0 Type VI secretion system, TssO Glyco_hydro_125 PF06824.11 KKK22779.1 - 2.4e-182 606.5 0.0 2.7e-182 606.3 0.0 1.0 1 0 0 1 1 1 1 Metal-independent alpha-mannosidase (GH125) zf-C3HC4_2 PF13923.6 KKK22780.1 - 6.6e-12 45.1 15.8 6.8e-11 41.8 12.7 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KKK22780.1 - 1.7e-07 31.0 16.5 2.3e-07 30.6 10.0 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KKK22780.1 - 1.9e-07 30.8 13.0 1.9e-07 30.8 13.0 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) SAP PF02037.27 KKK22780.1 - 4e-07 29.6 0.0 9.4e-07 28.5 0.0 1.7 1 0 0 1 1 1 1 SAP domain zf-RING_UBOX PF13445.6 KKK22780.1 - 5.2e-07 29.6 16.4 5.3e-07 29.6 11.3 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 KKK22780.1 - 1.4e-06 28.1 16.8 2.1e-06 27.6 13.1 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_6 PF14835.6 KKK22780.1 - 1.9e-06 27.7 8.0 2.5e-06 27.3 6.1 2.2 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-RING_2 PF13639.6 KKK22780.1 - 3.4e-05 24.1 18.5 4.3e-05 23.8 13.2 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_4 PF15227.6 KKK22780.1 - 4.3e-05 23.6 12.9 4.3e-05 23.6 12.9 2.3 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 KKK22780.1 - 0.00011 22.0 14.4 0.081 12.8 11.7 2.4 2 0 0 2 2 2 2 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 KKK22780.1 - 0.00031 21.0 7.2 0.00031 21.0 7.2 2.2 2 0 0 2 2 2 1 RING-H2 zinc finger domain Mob_synth_C PF06463.13 KKK22780.1 - 0.00032 20.6 2.0 0.00068 19.6 2.0 1.5 1 0 0 1 1 1 1 Molybdenum Cofactor Synthesis C zf-RING_10 PF16685.5 KKK22780.1 - 0.0039 17.3 6.6 0.0039 17.3 6.6 1.8 2 0 0 2 2 2 1 zinc RING finger of MSL2 U-box PF04564.15 KKK22780.1 - 0.069 13.3 0.0 0.17 12.1 0.0 1.6 1 0 0 1 1 1 0 U-box domain Rad50_zn_hook PF04423.14 KKK22780.1 - 0.13 12.1 3.8 2.1 8.3 0.1 2.6 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-RING_4 PF14570.6 KKK22780.1 - 0.26 11.1 13.4 0.37 10.6 9.8 2.6 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-ANAPC11 PF12861.7 KKK22780.1 - 0.66 10.1 7.0 0.13 12.3 3.1 1.9 2 0 0 2 2 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Di19 PF05605.12 KKK22780.1 - 0.72 10.2 0.1 0.72 10.2 0.1 2.9 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.7 KKK22780.1 - 1.2 9.7 0.1 1.2 9.7 0.1 2.8 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-WRNIP1_ubi PF18279.1 KKK22780.1 - 1.2 9.9 4.8 0.82 10.4 0.1 3.0 3 0 0 3 3 3 0 Werner helicase-interacting protein 1 ubiquitin-binding domain YdjO PF14169.6 KKK22780.1 - 1.5 8.6 7.3 12 5.7 0.0 3.3 3 0 0 3 3 3 0 Cold-inducible protein YdjO HypA PF01155.19 KKK22780.1 - 4.5 7.3 7.5 10 6.2 5.0 2.6 2 1 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA CDC27 PF09507.10 KKK22781.1 - 9.3e-112 374.5 18.1 1.1e-111 374.3 18.1 1.0 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 Ndc1_Nup PF09531.10 KKK22781.1 - 5.2 5.6 12.8 6.9 5.2 12.8 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Mitofilin PF09731.9 KKK22781.1 - 6.2 5.5 17.7 9.6 4.9 17.7 1.4 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Lung_7-TM_R PF06814.13 KKK22782.1 - 9.4e-71 238.5 15.0 1.1e-70 238.2 15.0 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor Septin PF00735.18 KKK22784.1 - 1.3e-10 41.1 0.0 1.5e-07 31.0 0.0 2.1 2 0 0 2 2 2 2 Septin ATP_bind_1 PF03029.17 KKK22784.1 - 0.012 15.4 0.0 0.023 14.5 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_16 PF13191.6 KKK22784.1 - 0.032 14.6 0.0 0.11 12.8 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain AAA_33 PF13671.6 KKK22784.1 - 0.052 13.7 0.0 0.14 12.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KKK22784.1 - 0.076 12.5 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_29 PF13555.6 KKK22784.1 - 0.078 12.7 0.1 0.27 11.0 0.1 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA PF00004.29 KKK22784.1 - 0.079 13.4 0.0 0.15 12.5 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 KKK22784.1 - 0.08 12.3 0.0 0.2 11.0 0.0 1.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 KKK22784.1 - 0.08 12.7 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 KKK22784.1 - 0.12 12.7 0.0 0.28 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 KKK22784.1 - 0.13 11.3 0.0 0.26 10.3 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein RsgA_GTPase PF03193.16 KKK22784.1 - 0.17 11.8 0.1 1.8 8.5 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase G-alpha PF00503.20 KKK22784.1 - 0.19 10.9 0.0 0.35 10.0 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit ABC_tran PF00005.27 KKK22784.1 - 0.19 12.3 0.0 0.66 10.5 0.0 1.9 2 0 0 2 2 2 0 ABC transporter Lactate_perm PF02652.14 KKK22786.1 - 1.1 7.9 9.2 0.76 8.4 0.3 2.6 3 0 0 3 3 3 0 L-lactate permease DNA_mis_repair PF01119.19 KKK22787.1 - 2.5e-19 69.1 0.0 1.1e-18 67.0 0.0 2.0 2 0 0 2 2 2 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 KKK22787.1 - 3e-10 40.1 0.0 5.5e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 KKK22787.1 - 1.7e-06 28.5 0.0 4.2e-06 27.2 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Fungal_trans_2 PF11951.8 KKK22788.1 - 2.7e-09 36.3 2.5 5.9e-08 31.9 2.5 2.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK22788.1 - 1.3e-06 28.4 6.4 2.7e-06 27.4 6.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Opy2 PF09463.10 KKK22788.1 - 6.7 7.1 6.6 93 3.5 5.2 2.5 2 0 0 2 2 2 0 Opy2 protein Aldedh PF00171.22 KKK22792.1 - 2.4e-34 118.7 0.0 2.7e-34 118.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Amino_oxidase PF01593.24 KKK22793.1 - 7.4e-54 183.7 0.1 9.1e-54 183.4 0.1 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Ribonuc_L-PSP PF01042.21 KKK22793.1 - 1.1e-16 60.9 0.0 2.3e-16 59.9 0.0 1.5 1 0 0 1 1 1 1 Endoribonuclease L-PSP NAD_binding_8 PF13450.6 KKK22793.1 - 3.1e-13 49.8 0.1 7.6e-13 48.5 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KKK22793.1 - 7.1e-09 35.2 0.7 1.1e-08 34.6 0.7 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 KKK22793.1 - 6.6e-07 29.0 0.7 9.6e-07 28.5 0.7 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.24 KKK22793.1 - 1.3e-06 28.3 0.8 3.6e-06 26.8 0.7 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 KKK22793.1 - 1.5e-06 27.6 0.3 2.9e-06 26.7 0.3 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.19 KKK22793.1 - 2.6e-06 26.9 0.3 6.6e-06 25.6 0.3 1.6 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 KKK22793.1 - 7.8e-06 25.2 0.6 1.4e-05 24.4 0.6 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KKK22793.1 - 0.00012 21.4 0.1 0.00029 20.2 0.1 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KKK22793.1 - 0.00058 18.7 0.2 0.00097 17.9 0.2 1.3 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.22 KKK22793.1 - 0.002 17.3 0.3 0.003 16.7 0.3 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 KKK22793.1 - 0.0052 16.1 0.1 0.012 14.9 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KKK22793.1 - 0.0088 16.6 0.1 0.02 15.4 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KKK22793.1 - 0.025 13.9 0.2 0.046 13.0 0.2 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DUF2407_C PF13373.6 KKK22798.1 - 1.1e-42 145.6 0.1 2e-42 144.7 0.1 1.4 1 0 0 1 1 1 1 DUF2407 C-terminal domain DUF2407 PF10302.9 KKK22798.1 - 4.2e-36 123.7 0.1 2.1e-35 121.4 0.0 2.0 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.23 KKK22798.1 - 0.00033 20.3 0.0 0.00057 19.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family V-SNARE PF05008.15 KKK22799.1 - 1.2e-21 76.9 6.7 1.2e-21 76.9 6.7 1.9 2 0 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.8 KKK22799.1 - 2.2e-18 66.3 3.7 2.2e-18 66.3 3.7 2.8 3 1 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus Prominin PF05478.11 KKK22799.1 - 0.0086 14.1 3.2 0.011 13.7 3.2 1.0 1 0 0 1 1 1 1 Prominin Thump_like PF18096.1 KKK22799.1 - 0.031 14.2 0.0 0.061 13.3 0.0 1.4 1 0 0 1 1 1 0 THUMP domain-like Vps23_core PF09454.10 KKK22799.1 - 0.068 13.1 0.2 0.61 10.1 0.0 2.2 2 0 0 2 2 2 0 Vps23 core domain TBCA PF02970.16 KKK22799.1 - 0.13 12.7 10.7 9.1 6.7 1.8 3.1 2 1 1 3 3 3 0 Tubulin binding cofactor A H-kinase_dim PF02895.14 KKK22799.1 - 1.6 9.2 5.9 10 6.6 1.4 2.4 2 0 0 2 2 2 0 Signal transducing histidine kinase, homodimeric domain Exonuc_VII_L PF02601.15 KKK22799.1 - 6.1 6.3 13.7 18 4.8 13.7 1.7 1 1 0 1 1 1 0 Exonuclease VII, large subunit DUF349 PF03993.12 KKK22799.1 - 6.6 7.1 7.0 2.4 8.5 0.5 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF349) zf-C4H2 PF10146.9 KKK22799.1 - 9.5 6.5 8.9 55 4.0 8.9 2.0 1 1 0 1 1 1 0 Zinc finger-containing protein Amino_oxidase PF01593.24 KKK22800.1 - 2.4e-13 50.2 0.0 3.9e-13 49.5 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KKK22800.1 - 3.5e-10 40.0 0.0 6.6e-10 39.1 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KKK22800.1 - 0.00052 20.0 0.0 0.37 10.8 0.0 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding DAO PF01266.24 KKK22800.1 - 0.0016 18.1 0.1 0.0047 16.6 0.1 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KKK22800.1 - 0.0018 17.6 0.0 0.033 13.4 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KKK22800.1 - 0.0074 16.8 0.1 0.14 12.8 0.1 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KKK22800.1 - 0.16 10.6 0.0 13 4.4 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein FAD_oxidored PF12831.7 KKK22800.1 - 0.25 10.6 0.0 0.36 10.1 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase TIP49 PF06068.13 KKK22801.1 - 2.3e-146 487.5 2.8 2.3e-110 369.1 0.2 2.0 1 1 1 2 2 2 2 TIP49 P-loop domain TIP49_C PF17856.1 KKK22801.1 - 9.6e-21 73.7 0.0 3.7e-20 71.8 0.0 2.0 2 0 0 2 2 2 1 TIP49 AAA-lid domain RuvB_N PF05496.12 KKK22801.1 - 1.4e-10 41.1 0.1 5.8e-07 29.4 0.0 2.3 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA PF00004.29 KKK22801.1 - 4.4e-09 36.9 0.2 5e-05 23.7 0.1 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KKK22801.1 - 8.1e-05 22.9 0.2 0.081 13.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KKK22801.1 - 9.8e-05 22.8 0.0 0.00042 20.7 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 KKK22801.1 - 0.00064 19.7 0.2 0.16 12.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.6 KKK22801.1 - 0.001 19.4 3.6 0.023 15.1 3.6 2.2 1 1 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 KKK22801.1 - 0.0014 18.3 0.1 1.3 8.7 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain Zeta_toxin PF06414.12 KKK22801.1 - 0.0059 15.9 0.2 0.014 14.6 0.2 1.6 1 0 0 1 1 1 1 Zeta toxin AAA_25 PF13481.6 KKK22801.1 - 0.0067 16.0 0.1 0.016 14.8 0.1 1.5 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 KKK22801.1 - 0.018 14.5 0.3 0.83 9.0 0.1 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 KKK22801.1 - 0.048 13.4 0.0 0.087 12.5 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein ATPase PF06745.13 KKK22801.1 - 0.071 12.4 1.5 0.15 11.3 0.1 2.1 3 0 0 3 3 3 0 KaiC AAA_14 PF13173.6 KKK22801.1 - 0.078 13.0 0.0 0.72 9.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KKK22801.1 - 0.09 13.3 0.1 0.4 11.2 0.1 2.1 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 KKK22801.1 - 0.092 13.0 0.1 0.22 11.8 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KKK22801.1 - 0.1 12.3 0.3 1.6 8.4 0.1 2.3 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KKK22801.1 - 0.13 11.7 0.2 0.5 9.9 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region NACHT PF05729.12 KKK22801.1 - 0.15 12.0 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 NACHT domain DUF2075 PF09848.9 KKK22801.1 - 0.15 11.2 0.1 0.24 10.6 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Ribosomal_L28 PF00830.19 KKK22802.1 - 3.1e-18 65.7 1.1 6.7e-18 64.6 1.1 1.6 1 0 0 1 1 1 1 Ribosomal L28 family Glyco_transf_34 PF05637.12 KKK22803.1 - 2.8e-62 210.6 0.0 3.5e-62 210.2 0.0 1.1 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Steroid_dh PF02544.16 KKK22804.1 - 3.2e-31 108.3 0.2 4.4e-31 107.9 0.2 1.2 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 KKK22804.1 - 5.8e-05 22.7 0.3 8.6e-05 22.2 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.13 KKK22804.1 - 0.014 15.8 1.3 0.02 15.3 0.2 1.8 2 0 0 2 2 2 0 Phospholipid methyltransferase An_peroxidase PF03098.15 KKK22805.1 - 1.8e-37 129.1 0.0 4.3e-28 98.2 0.0 3.2 1 1 1 2 2 2 2 Animal haem peroxidase p450 PF00067.22 KKK22805.1 - 1.3e-09 37.3 0.0 1.2e-08 34.2 0.0 2.0 2 0 0 2 2 2 1 Cytochrome P450 DUF1741 PF08427.10 KKK22806.1 - 1.1e-91 306.7 0.3 2.3e-91 305.6 0.1 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF1741) Fe-S_biosyn PF01521.20 KKK22807.1 - 2.3e-19 69.6 0.0 3.1e-19 69.2 0.0 1.2 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis MRG PF05712.13 KKK22808.1 - 4e-58 196.0 0.4 6.3e-58 195.4 0.4 1.3 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.8 KKK22808.1 - 4.7e-10 39.2 4.1 8.4e-10 38.4 3.2 2.0 2 0 0 2 2 2 1 RNA binding activity-knot of a chromodomain Chromo PF00385.24 KKK22808.1 - 0.0026 17.6 1.1 0.0088 15.9 1.1 1.9 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain PWWP PF00855.17 KKK22808.1 - 0.028 14.8 1.1 0.042 14.2 0.1 1.8 2 0 0 2 2 2 0 PWWP domain Cnl2_NKP2 PF09447.10 KKK22809.1 - 4.8e-27 93.9 1.2 9.2e-27 93.0 1.2 1.5 1 0 0 1 1 1 1 Cnl2/NKP2 family protein APG6_N PF17675.1 KKK22809.1 - 0.012 16.1 0.2 0.031 14.8 0.1 1.7 1 1 0 1 1 1 0 Apg6 coiled-coil region Ctf8 PF09696.10 KKK22810.1 - 5e-31 108.0 0.0 5.6e-31 107.8 0.0 1.0 1 0 0 1 1 1 1 Ctf8 SecY PF00344.20 KKK22811.1 - 4.5e-48 164.1 4.1 6.2e-48 163.6 4.1 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 KKK22811.1 - 2.5e-17 62.4 0.3 6.5e-17 61.1 0.3 1.8 1 0 0 1 1 1 1 Plug domain of Sec61p SecY PF00344.20 KKK22812.1 - 8.6e-20 71.2 0.0 9.3e-20 71.1 0.0 1.0 1 0 0 1 1 1 1 SecY translocase FUN14 PF04930.15 KKK22813.1 - 2.3e-10 40.7 0.5 4.5e-10 39.8 0.5 1.5 1 0 0 1 1 1 1 FUN14 family DUF543 PF04418.12 KKK22813.1 - 0.17 11.9 3.8 0.39 10.7 2.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF543) ORC2 PF04084.14 KKK22814.1 - 1.5e-119 398.9 0.0 1.8e-119 398.6 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 2 ORC6 PF05460.13 KKK22814.1 - 5.2 6.2 13.7 3.9 6.7 11.4 2.0 1 1 2 3 3 3 0 Origin recognition complex subunit 6 (ORC6) Promethin PF16015.5 KKK22815.1 - 3.9e-08 33.2 17.2 3.9e-08 33.2 17.2 2.1 1 1 1 2 2 2 1 Promethin SSFA2_C PF14723.6 KKK22815.1 - 0.16 11.9 4.0 0.23 11.3 4.0 1.3 1 0 0 1 1 1 0 Sperm-specific antigen 2 C-terminus DUF4707 PF15806.5 KKK22815.1 - 0.43 9.5 4.1 0.58 9.0 4.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4707) Stevor PF17410.2 KKK22815.1 - 2.3 7.7 6.7 4.1 6.9 6.7 1.3 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame SRP-alpha_N PF04086.13 KKK22815.1 - 7.9 6.3 8.2 9.1 6.1 8.2 1.0 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal SOR_SNZ PF01680.17 KKK22816.1 - 5.6e-108 359.5 3.1 7.9e-108 359.0 3.1 1.2 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.14 KKK22816.1 - 7.4e-10 38.6 2.9 3.4e-06 26.5 0.1 2.4 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG TetR_C_27 PF17935.1 KKK22816.1 - 0.00088 19.3 0.0 0.0024 17.9 0.0 1.7 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain Dus PF01207.17 KKK22816.1 - 0.002 17.3 1.2 0.83 8.7 0.0 2.5 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 KKK22816.1 - 0.0042 16.6 0.1 0.051 13.0 0.0 2.4 2 1 0 2 2 2 1 Histidine biosynthesis protein IGPS PF00218.21 KKK22816.1 - 0.0065 15.7 0.0 0.53 9.4 0.0 2.4 2 0 0 2 2 2 1 Indole-3-glycerol phosphate synthase NanE PF04131.14 KKK22816.1 - 0.025 13.8 0.9 0.29 10.3 0.0 2.5 2 1 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase TMP-TENI PF02581.17 KKK22816.1 - 0.086 12.2 1.3 1.2 8.4 0.0 3.0 3 0 0 3 3 3 0 Thiamine monophosphate synthase NMO PF03060.15 KKK22816.1 - 0.21 11.0 6.5 0.34 10.2 0.1 2.3 2 0 0 2 2 2 0 Nitronate monooxygenase Aminotran_4 PF01063.19 KKK22817.1 - 1.9e-35 122.8 0.0 2.6e-35 122.3 0.0 1.2 1 0 0 1 1 1 1 Amino-transferase class IV zf-LITAF-like PF10601.9 KKK22827.1 - 8.8e-21 74.0 7.5 1.1e-20 73.7 7.5 1.1 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain Zn-ribbon_8 PF09723.10 KKK22827.1 - 0.0061 16.6 0.5 0.07 13.3 0.2 2.2 2 0 0 2 2 2 1 Zinc ribbon domain TF_Zn_Ribbon PF08271.12 KKK22827.1 - 0.038 13.5 1.0 6.7 6.3 0.1 2.3 2 0 0 2 2 2 0 TFIIB zinc-binding Zn_ribbon_SprT PF17283.2 KKK22827.1 - 0.62 10.0 5.3 0.28 11.1 0.9 2.1 2 0 0 2 2 2 0 SprT-like zinc ribbon domain NAD_binding_11 PF14833.6 KKK22828.1 - 3.9e-39 133.7 2.8 1.8e-27 96.0 0.0 2.6 3 0 0 3 3 3 2 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase NAD_binding_2 PF03446.15 KKK22828.1 - 4.4e-38 130.9 0.1 7.9e-38 130.1 0.1 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 KKK22828.1 - 0.0014 18.5 0.1 0.0035 17.2 0.0 1.7 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.17 KKK22828.1 - 0.003 18.1 0.0 0.015 15.8 0.0 2.2 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent F_bP_aldolase PF01116.20 KKK22829.1 - 8.7e-85 284.6 0.0 9.8e-85 284.4 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II Methyltransf_24 PF13578.6 KKK22829.1 - 0.03 15.3 0.1 0.059 14.4 0.1 1.5 1 0 0 1 1 1 0 Methyltransferase domain DUF2007 PF09413.10 KKK22829.1 - 0.061 13.5 0.2 0.19 11.9 0.2 1.8 1 0 0 1 1 1 0 Putative prokaryotic signal transducing protein PTE PF02126.18 KKK22829.1 - 0.14 11.5 0.1 0.23 10.9 0.1 1.2 1 0 0 1 1 1 0 Phosphotriesterase family Fer2_3 PF13085.6 KKK22830.1 - 9.4e-32 109.3 0.0 1.5e-31 108.6 0.0 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.6 KKK22830.1 - 1e-08 35.6 5.8 1e-08 35.6 5.8 2.3 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 KKK22830.1 - 3.5e-07 30.2 3.0 3.5e-07 30.2 3.0 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 KKK22830.1 - 1.4e-06 28.7 13.0 1.8e-06 28.3 8.9 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer2 PF00111.27 KKK22830.1 - 0.0085 16.0 0.3 0.0085 16.0 0.3 2.2 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_7 PF12838.7 KKK22830.1 - 0.0099 16.5 5.9 0.0099 16.5 5.9 2.4 2 2 0 2 2 2 1 4Fe-4S dicluster domain Fer4_18 PF13746.6 KKK22830.1 - 0.13 12.5 5.4 0.4 10.9 0.1 2.9 3 1 0 3 3 3 0 4Fe-4S dicluster domain Fer4_9 PF13187.6 KKK22830.1 - 3.6 7.8 12.8 19 5.5 10.0 2.9 2 1 2 4 4 4 0 4Fe-4S dicluster domain Nitroreductase PF00881.24 KKK22831.1 - 4.6e-15 56.1 0.0 5.3e-15 55.9 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family MCRA PF06100.11 KKK22832.1 - 3.4e-159 530.8 0.0 4.1e-159 530.6 0.0 1.0 1 0 0 1 1 1 1 MCRA family NAD_binding_8 PF13450.6 KKK22832.1 - 0.00018 21.7 0.1 0.00037 20.6 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KKK22832.1 - 0.0093 15.6 0.9 0.35 10.4 0.4 2.6 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KKK22832.1 - 0.15 12.0 0.1 0.32 11.0 0.1 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding Pec_lyase_C PF00544.19 KKK22833.1 - 5.6e-17 62.0 8.0 5.8e-15 55.5 8.0 2.2 1 1 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 KKK22833.1 - 2e-05 24.5 13.1 0.00061 19.7 12.0 2.3 1 1 1 2 2 2 2 Right handed beta helix region PMP1_2 PF08114.11 KKK22834.1 - 0.0026 17.5 0.3 0.0053 16.5 0.3 1.5 1 0 0 1 1 1 1 ATPase proteolipid family Zn_clus PF00172.18 KKK22835.1 - 3e-10 40.1 11.3 6.3e-10 39.0 11.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KKK22835.1 - 0.00025 20.0 0.1 0.0004 19.3 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF1422 PF07226.11 KKK22835.1 - 0.12 12.3 0.1 0.27 11.2 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1422) RTA1 PF04479.13 KKK22836.1 - 1.7e-55 187.9 8.6 2.2e-55 187.5 8.6 1.1 1 0 0 1 1 1 1 RTA1 like protein SUR7 PF06687.12 KKK22836.1 - 0.63 9.6 3.7 1.2 8.7 3.7 1.4 1 0 0 1 1 1 0 SUR7/PalI family GPI-anchored PF10342.9 KKK22837.1 - 3.5e-23 82.2 0.1 3.5e-23 82.2 0.1 3.3 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family BAF1_ABF1 PF04684.13 KKK22837.1 - 2.7 6.9 8.3 3.3 6.7 8.3 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF5305 PF17231.2 KKK22837.1 - 3.3 7.1 15.4 4.9 6.5 15.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5305) SWI-SNF_Ssr4 PF08549.10 KKK22837.1 - 3.8 6.0 17.2 4.7 5.7 17.2 1.0 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) Aldedh PF00171.22 KKK22838.1 - 8e-132 440.0 1.2 9.8e-132 439.7 1.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family CN_hydrolase PF00795.22 KKK22839.1 - 2e-61 207.6 0.0 2.3e-61 207.4 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Ribosomal_L31e PF01198.19 KKK22841.1 - 2.9e-41 139.6 0.5 3.8e-41 139.2 0.5 1.2 1 0 0 1 1 1 1 Ribosomal protein L31e TPR_12 PF13424.6 KKK22842.1 - 9.8e-17 61.0 0.0 2.6e-13 50.1 0.0 2.8 2 1 1 3 3 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 KKK22842.1 - 1.8e-16 59.4 0.0 3.9e-06 26.6 0.0 3.9 4 0 0 4 4 4 3 Tetratricopeptide repeat PNP_UDP_1 PF01048.20 KKK22842.1 - 5.3e-13 48.8 0.4 3.2e-12 46.2 0.4 2.1 1 1 0 1 1 1 1 Phosphorylase superfamily NB-ARC PF00931.22 KKK22842.1 - 2.7e-12 46.4 0.1 7.2e-12 45.0 0.0 1.7 2 0 0 2 2 2 1 NB-ARC domain AAA_16 PF13191.6 KKK22842.1 - 1e-08 35.7 0.1 4e-07 30.6 0.1 2.5 1 1 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 KKK22842.1 - 1.7e-07 31.3 0.0 3.9e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 NACHT domain TPR_7 PF13176.6 KKK22842.1 - 1.1e-05 25.1 0.0 0.3 11.2 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat AAA_22 PF13401.6 KKK22842.1 - 0.00064 20.0 0.0 0.0018 18.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 KKK22842.1 - 0.004 17.2 0.0 0.014 15.4 0.0 1.9 2 0 0 2 2 1 1 AAA domain ATPase_2 PF01637.18 KKK22842.1 - 0.006 16.5 0.0 0.012 15.6 0.0 1.5 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea TPR_1 PF00515.28 KKK22842.1 - 0.0093 15.8 0.0 1.6 8.7 0.0 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 KKK22842.1 - 0.014 15.5 0.1 7.8 6.9 0.0 3.6 4 0 0 4 4 3 0 Tetratricopeptide repeat ResIII PF04851.15 KKK22842.1 - 0.02 14.9 0.0 0.043 13.8 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit TPR_6 PF13174.6 KKK22842.1 - 0.042 14.5 0.1 2.7 8.8 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat AAA PF00004.29 KKK22842.1 - 0.048 14.1 0.0 0.19 12.2 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) TPR_3 PF07720.12 KKK22842.1 - 0.079 13.0 0.1 1.3 9.1 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_MalT PF17874.1 KKK22842.1 - 0.088 12.2 0.0 0.36 10.2 0.0 1.9 2 0 0 2 2 2 0 MalT-like TPR region ERAP1_C PF11838.8 KKK22842.1 - 0.12 11.9 0.3 0.27 10.7 0.0 1.7 2 0 0 2 2 2 0 ERAP1-like C-terminal domain SRP54 PF00448.22 KKK22842.1 - 0.14 11.8 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain HSP70 PF00012.20 KKK22843.1 - 5.6e-262 870.3 8.2 6.4e-262 870.1 8.2 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KKK22843.1 - 1.4e-18 66.8 0.0 1.6e-17 63.3 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 KKK22843.1 - 0.0011 18.7 0.0 0.0037 17.0 0.0 1.8 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 KKK22843.1 - 0.008 16.6 6.6 4.7 7.7 0.2 3.7 3 2 0 3 3 3 2 Cell division protein FtsA Hydantoinase_A PF01968.18 KKK22843.1 - 0.025 13.8 0.1 0.058 12.6 0.1 1.6 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase BcrAD_BadFG PF01869.20 KKK22843.1 - 0.037 13.5 0.1 1.3 8.5 0.0 2.4 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family StbA PF06406.11 KKK22843.1 - 0.042 13.1 0.0 0.083 12.1 0.0 1.4 1 0 0 1 1 1 0 StbA protein Peptidase_C13 PF01650.18 KKK22844.1 - 9.7e-06 25.3 0.0 1.5e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase C13 family APH PF01636.23 KKK22845.1 - 1.8e-07 31.3 0.2 2.8e-05 24.2 0.1 2.3 2 0 0 2 2 2 2 Phosphotransferase enzyme family Choline_kinase PF01633.20 KKK22845.1 - 0.043 13.4 0.0 0.091 12.3 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase CHZ PF09649.10 KKK22846.1 - 2.9e-17 61.8 1.1 2.9e-17 61.8 1.1 2.5 2 0 0 2 2 2 1 Histone chaperone domain CHZ Mcl1_mid PF12341.8 KKK22848.1 - 1.5e-102 343.0 0.0 4.4e-102 341.4 0.0 1.8 2 0 0 2 2 2 1 Minichromosome loss protein, Mcl1, middle region WD40 PF00400.32 KKK22848.1 - 2.1e-18 66.3 0.6 1.2e-06 29.1 0.1 7.2 9 0 0 9 9 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKK22848.1 - 2.2e-16 59.9 0.0 3.2e-05 24.1 0.1 6.8 3 1 4 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 KKK22848.1 - 2.1e-07 30.4 0.0 5.3e-06 25.7 0.0 2.4 1 1 1 2 2 2 1 Coatomer WD associated region eIF2A PF08662.11 KKK22848.1 - 0.00025 21.0 0.1 0.012 15.5 0.0 2.6 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 KKK22848.1 - 0.0016 18.3 0.1 3.2 7.8 0.0 4.3 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KKK22848.1 - 0.0093 15.0 0.1 5.6 5.8 0.0 3.1 1 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein MMS1_N PF10433.9 KKK22848.1 - 0.01 14.5 0.0 0.096 11.3 0.0 2.4 3 0 0 3 3 3 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term Lactonase PF10282.9 KKK22848.1 - 0.02 14.2 0.0 0.5 9.6 0.0 2.2 1 1 2 3 3 3 0 Lactonase, 7-bladed beta-propeller DNA_pol_alpha_N PF12254.8 KKK22848.1 - 0.022 14.8 2.9 0.06 13.4 2.9 1.7 1 0 0 1 1 1 0 DNA polymerase alpha subunit p180 N terminal Frtz PF11768.8 KKK22848.1 - 0.047 12.0 0.0 0.59 8.4 0.0 2.1 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz IKI3 PF04762.12 KKK22848.1 - 0.051 11.6 0.6 0.18 9.8 0.0 2.1 2 1 0 2 2 2 0 IKI3 family TFIIIC_delta PF12657.7 KKK22848.1 - 0.086 12.8 0.1 2.4 8.1 0.1 2.6 2 1 0 2 2 2 0 Transcription factor IIIC subunit delta N-term PQQ_2 PF13360.6 KKK22848.1 - 0.089 12.4 0.4 0.35 10.4 0.2 2.2 3 0 0 3 3 3 0 PQQ-like domain MFS_1 PF07690.16 KKK22849.1 - 2.1e-39 135.5 47.6 5.5e-37 127.5 22.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KKK22849.1 - 3.1e-08 32.9 5.8 3.1e-08 32.9 5.8 1.8 1 1 1 2 2 2 1 Sugar (and other) transporter MFS_5 PF05631.14 KKK22849.1 - 0.001 18.0 1.7 0.0021 17.0 1.1 1.8 1 1 1 2 2 2 1 Sugar-tranasporters, 12 TM OATP PF03137.20 KKK22849.1 - 0.0014 17.0 3.1 0.0051 15.2 3.1 1.8 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MFS_4 PF06779.14 KKK22849.1 - 0.0087 15.4 6.9 0.0087 15.4 6.9 2.6 2 1 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB DUF1129 PF06570.11 KKK22849.1 - 0.079 12.4 0.5 6.3 6.2 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) DUF515 PF04415.12 KKK22849.1 - 0.64 8.4 6.7 0.86 7.9 6.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) MGC-24 PF05283.11 KKK22849.1 - 8.3 6.9 12.9 20 5.6 12.9 1.6 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin MMU163 PF17119.5 KKK22850.1 - 9.9e-102 339.3 0.0 1.4e-101 338.9 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial protein up-regulated during meiosis Acetyltransf_1 PF00583.25 KKK22851.1 - 3.4e-15 56.3 0.0 4.3e-15 56.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 KKK22851.1 - 8.5e-08 32.1 0.0 1.4e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 KKK22851.1 - 1e-07 32.3 0.0 1.5e-07 31.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KKK22851.1 - 3.1e-05 23.9 0.0 4.7e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KKK22851.1 - 0.0018 18.9 0.0 0.0023 18.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KKK22851.1 - 0.2 11.8 0.0 0.3 11.2 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain GRIP PF01465.20 KKK22852.1 - 3.7e-16 58.8 0.2 8.6e-16 57.6 0.2 1.7 1 0 0 1 1 1 1 GRIP domain GAS PF13851.6 KKK22852.1 - 5.8e-09 35.6 150.8 0.013 14.9 19.9 10.5 2 2 6 9 9 9 8 Growth-arrest specific micro-tubule binding Spc7 PF08317.11 KKK22852.1 - 1.1e-06 27.8 150.1 0.009 14.9 11.4 8.0 2 2 6 8 8 8 5 Spc7 kinetochore protein CALCOCO1 PF07888.11 KKK22852.1 - 0.0013 17.8 31.4 0.0013 17.8 31.4 5.1 2 2 2 4 4 3 1 Calcium binding and coiled-coil domain (CALCOCO1) like CENP-F_leu_zip PF10473.9 KKK22852.1 - 0.0014 18.7 27.1 0.0014 18.7 27.1 9.8 2 2 7 9 9 8 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DHR10 PF18595.1 KKK22852.1 - 0.0014 18.7 12.3 0.0014 18.7 12.3 11.7 4 3 5 10 10 9 3 Designed helical repeat protein 10 domain Bap31_Bap29_C PF18035.1 KKK22852.1 - 0.0018 18.3 3.1 0.0018 18.3 3.1 11.9 12 3 0 12 12 10 2 Bap31/Bap29 cytoplasmic coiled-coil domain Atg14 PF10186.9 KKK22852.1 - 0.002 17.3 10.7 0.002 17.3 10.7 7.5 2 2 5 7 7 7 4 Vacuolar sorting 38 and autophagy-related subunit 14 KASH_CCD PF14662.6 KKK22852.1 - 0.005 16.7 19.1 0.005 16.7 19.1 7.4 2 2 3 6 6 5 1 Coiled-coil region of CCDC155 or KASH BRE1 PF08647.11 KKK22852.1 - 0.011 15.8 9.8 0.011 15.8 9.8 10.9 3 2 8 12 12 11 0 BRE1 E3 ubiquitin ligase FPP PF05911.11 KKK22852.1 - 0.19 9.9 138.6 0.016 13.4 20.4 6.2 1 1 5 6 6 6 0 Filament-like plant protein, long coiled-coil Fez1 PF06818.15 KKK22852.1 - 0.24 11.8 145.0 0.11 13.0 17.6 7.5 2 2 5 7 7 7 0 Fez1 ATG16 PF08614.11 KKK22852.1 - 0.25 11.6 175.6 0.082 13.1 17.8 10.0 2 2 7 9 9 8 0 Autophagy protein 16 (ATG16) Cep57_CLD PF14073.6 KKK22852.1 - 0.63 10.0 0.0 0.63 10.0 0.0 7.5 4 2 3 7 7 5 0 Centrosome localisation domain of Cep57 HMMR_N PF15905.5 KKK22852.1 - 0.74 9.2 145.5 0.074 12.5 53.1 7.1 1 1 5 7 7 7 0 Hyaluronan mediated motility receptor N-terminal ERM PF00769.19 KKK22852.1 - 1.2 8.9 170.9 0.11 12.3 35.5 6.7 2 2 2 5 5 3 0 Ezrin/radixin/moesin family Filament PF00038.21 KKK22852.1 - 1.5 8.3 130.2 0.3 10.6 46.7 7.1 2 2 4 6 6 6 0 Intermediate filament protein DUF5082 PF16888.5 KKK22852.1 - 6.1 7.1 100.0 0.049 13.9 5.7 9.1 4 2 3 8 8 8 0 Domain of unknown function (DUF5082) Zn_clus PF00172.18 KKK22861.1 - 2.1e-05 24.6 13.3 2.1e-05 24.6 13.3 2.3 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2054 PF10218.9 KKK22861.1 - 0.098 12.7 6.9 0.16 12.1 4.8 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2054) Nse4-Nse3_bdg PF15412.6 KKK22862.1 - 0.047 13.8 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 Binding domain of Nse4/EID3 to Nse3-MAGE CTV_P6 PF06706.11 KKK22864.1 - 2.9 7.7 8.8 1.9 8.2 5.1 2.5 2 0 0 2 2 2 0 Citrus tristeza virus 6-kDa protein Glyco_hydro_31 PF01055.26 KKK22865.1 - 1.7e-89 301.0 0.7 2.5e-89 300.5 0.7 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 KKK22865.1 - 9.3e-13 48.3 0.1 2.9e-12 46.7 0.1 1.9 1 0 0 1 1 1 1 Galactose mutarotase-like DUF5110 PF17137.4 KKK22865.1 - 0.0037 17.5 0.0 0.009 16.3 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF5110) MFS_1 PF07690.16 KKK22866.1 - 1e-19 70.7 26.5 1.6e-19 70.0 25.9 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Fungal_trans PF04082.18 KKK22866.1 - 4.3e-08 32.5 0.0 8.7e-08 31.5 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK22866.1 - 3.5e-05 23.8 6.2 7.2e-05 22.8 6.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dioxygenase_C PF00775.21 KKK22867.1 - 1.1e-39 135.7 0.0 1.5e-39 135.4 0.0 1.1 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 KKK22867.1 - 2.7e-24 84.8 0.0 4.5e-24 84.1 0.0 1.4 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.6 KKK22867.1 - 0.19 12.0 0.0 0.64 10.3 0.0 1.8 1 1 0 1 1 1 0 Carboxypeptidase regulatory-like domain Yip1 PF04893.17 KKK22868.1 - 0.018 14.7 3.1 13 5.4 0.0 3.0 3 0 0 3 3 3 0 Yip1 domain TrbC PF04956.13 KKK22868.1 - 0.095 12.9 0.7 1.6 9.0 0.0 2.2 2 0 0 2 2 2 0 TrbC/VIRB2 family GLEYA PF10528.9 KKK22869.1 - 7.4e-13 48.7 0.8 7.4e-13 48.7 0.8 2.0 2 0 0 2 2 2 1 GLEYA domain Glyco_hydro_11 PF00457.17 KKK22870.1 - 2.7e-77 258.4 21.2 3.1e-77 258.2 21.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 Sugar_tr PF00083.24 KKK22872.1 - 6.3e-126 420.9 17.6 7.2e-126 420.7 17.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKK22872.1 - 1.7e-21 76.6 23.3 1.7e-21 76.6 23.3 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily APH PF01636.23 KKK22873.1 - 3.6e-09 36.9 0.0 0.00021 21.3 0.0 2.4 2 0 0 2 2 2 2 Phosphotransferase enzyme family Choline_kinase PF01633.20 KKK22873.1 - 0.0048 16.5 0.0 0.0088 15.7 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 KKK22874.1 - 1.4e-11 44.8 0.1 2.5e-10 40.7 0.1 2.2 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 KKK22874.1 - 0.13 11.6 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase FAM83 PF07894.12 KKK22874.1 - 0.14 11.7 0.0 0.29 10.6 0.0 1.5 1 0 0 1 1 1 0 FAM83 A-H DUF1947 PF09183.10 KKK22874.1 - 0.33 11.3 1.8 3.2 8.1 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1947) CRC_subunit PF08624.10 KKK22875.1 - 2e-52 177.2 0.1 3e-52 176.6 0.1 1.2 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit His_Phos_1 PF00300.22 KKK22876.1 - 4.2e-05 23.3 0.5 0.00017 21.4 0.5 2.0 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Sds3 PF08598.11 KKK22876.1 - 0.078 13.0 2.6 7.7 6.4 0.0 2.1 2 0 0 2 2 2 0 Sds3-like Homeodomain PF00046.29 KKK22877.1 - 0.18 11.7 4.9 0.4 10.6 4.1 2.1 2 0 0 2 2 2 0 Homeodomain Vfa1 PF08432.10 KKK22877.1 - 5.8 7.2 16.2 12 6.2 16.2 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Snf7 PF03357.21 KKK22889.1 - 1.2e-44 151.9 15.4 1.6e-44 151.6 15.4 1.1 1 0 0 1 1 1 1 Snf7 CLZ PF16526.5 KKK22889.1 - 0.00058 20.2 2.9 0.35 11.3 0.0 3.5 2 1 1 3 3 3 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Zwint PF15556.6 KKK22889.1 - 0.0021 17.6 3.2 0.0026 17.3 3.2 1.3 1 0 0 1 1 1 1 ZW10 interactor NPV_P10 PF05531.12 KKK22889.1 - 0.023 15.2 5.5 0.2 12.2 0.5 2.7 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF4201 PF13870.6 KKK22889.1 - 0.023 14.4 8.4 0.024 14.4 6.2 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) Prefoldin_2 PF01920.20 KKK22889.1 - 0.029 14.3 7.8 0.25 11.3 0.0 3.4 2 1 1 3 3 3 0 Prefoldin subunit DUF848 PF05852.11 KKK22889.1 - 0.031 14.4 3.8 0.05 13.7 2.9 1.8 2 1 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) HHH_2 PF12826.7 KKK22889.1 - 0.04 14.0 0.0 0.081 13.0 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix motif FlaC_arch PF05377.11 KKK22889.1 - 0.21 12.0 6.3 8.6 6.8 0.0 3.3 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) FapA PF03961.13 KKK22889.1 - 1.9 7.0 8.4 2.2 6.8 4.2 1.9 1 1 1 2 2 2 0 Flagellar Assembly Protein A XhlA PF10779.9 KKK22889.1 - 5.5 7.3 6.0 59 4.0 0.0 3.5 2 1 1 3 3 3 0 Haemolysin XhlA Drf_GBD PF06371.13 KKK22890.1 - 1.8e-16 60.3 2.0 6.4e-15 55.2 2.0 2.5 1 1 0 1 1 1 1 Diaphanous GTPase-binding Domain Nramp PF01566.18 KKK22891.1 - 3.7e-94 315.6 20.7 8.2e-94 314.5 20.7 1.6 1 1 0 1 1 1 1 Natural resistance-associated macrophage protein Ribosomal_L6 PF00347.23 KKK22892.1 - 7.4e-24 84.2 0.1 7.4e-12 45.8 0.0 2.6 2 1 0 2 2 2 2 Ribosomal protein L6 Inositol_P PF00459.25 KKK22893.1 - 3.5e-52 177.6 0.5 9.1e-52 176.2 0.5 1.6 1 1 0 1 1 1 1 Inositol monophosphatase family Proteasome PF00227.26 KKK22894.1 - 1.4e-61 207.4 0.2 1.7e-61 207.1 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KKK22894.1 - 3.5e-13 49.0 0.1 8.9e-13 47.7 0.1 1.8 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DUF5624 PF18538.1 KKK22894.1 - 0.015 15.4 0.5 0.046 13.8 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5624) 4HBT PF03061.22 KKK22895.1 - 8.2e-09 35.7 0.1 1.5e-08 34.9 0.1 1.4 1 0 0 1 1 1 1 Thioesterase superfamily DEAD PF00270.29 KKK22896.1 - 5e-41 140.4 0.0 1e-40 139.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KKK22896.1 - 1.6e-27 96.1 0.0 8.9e-27 93.6 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KKK22896.1 - 0.017 15.2 0.5 0.064 13.3 0.0 2.1 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Presenilin PF01080.17 KKK22896.1 - 5.6 5.6 5.0 10 4.8 5.0 1.3 1 0 0 1 1 1 0 Presenilin IL17R_fnIII_D2 PF16578.5 KKK22897.1 - 0.16 12.5 0.0 0.23 12.0 0.0 1.4 1 0 0 1 1 1 0 Interleukin 17 receptor D FtsJ PF01728.19 KKK22898.1 - 9.3e-54 182.2 0.0 1.5e-53 181.5 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase NAD_binding_10 PF13460.6 KKK22899.1 - 2.7e-08 33.9 0.4 3.5e-08 33.5 0.4 1.3 1 0 0 1 1 1 1 NAD(P)H-binding HIM1 PF08732.10 KKK22899.1 - 1.5e-06 27.8 0.0 2.4e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 HIM1 Epimerase PF01370.21 KKK22899.1 - 2.7e-05 23.8 0.0 5.9e-05 22.6 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KKK22899.1 - 5.6e-05 22.8 0.5 9.7e-05 22.0 0.0 1.6 2 0 0 2 2 2 1 NmrA-like family Semialdhyde_dh PF01118.24 KKK22899.1 - 7.5e-05 23.2 0.1 0.0031 17.9 0.0 2.2 1 1 1 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.12 KKK22899.1 - 0.0015 17.8 0.1 0.81 8.8 0.0 2.1 1 1 1 2 2 2 2 Male sterility protein DapB_N PF01113.20 KKK22899.1 - 0.063 13.4 0.0 0.47 10.6 0.0 2.1 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus UQ_con PF00179.26 KKK22900.1 - 2e-35 121.5 0.2 2.3e-35 121.3 0.2 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme APG12 PF04110.13 KKK22901.1 - 1.4e-30 105.5 0.0 2.7e-30 104.6 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.16 KKK22901.1 - 0.056 13.6 0.0 0.073 13.3 0.0 1.2 1 0 0 1 1 1 0 Autophagy protein Atg8 ubiquitin like Ufm1 PF03671.14 KKK22901.1 - 0.069 13.2 0.2 0.13 12.4 0.2 1.4 1 0 0 1 1 1 0 Ubiquitin fold modifier 1 protein DUF2011 PF09428.10 KKK22902.1 - 9.8e-32 109.1 0.8 4.5e-31 106.9 0.0 2.2 2 0 0 2 2 2 1 Fungal protein of unknown function (DUF2011) VIR_N PF15912.5 KKK22902.1 - 0.6 9.7 12.3 0.28 10.8 4.9 2.1 2 0 0 2 2 2 0 Virilizer, N-terminal LAMTOR PF15454.6 KKK22903.1 - 9.2e-20 71.0 0.2 1.5e-19 70.3 0.2 1.4 1 0 0 1 1 1 1 Late endosomal/lysosomal adaptor and MAPK and MTOR activator VHS PF00790.19 KKK22904.1 - 2.8e-24 85.6 0.0 6.8e-24 84.3 0.0 1.6 1 0 0 1 1 1 1 VHS domain GAT PF03127.14 KKK22904.1 - 1.4e-06 28.5 0.3 3.2e-06 27.3 0.3 1.7 1 1 0 1 1 1 1 GAT domain ENTH PF01417.20 KKK22904.1 - 0.0013 18.8 0.0 0.0056 16.7 0.0 2.0 2 0 0 2 2 2 1 ENTH domain Hrs_helical PF12210.8 KKK22904.1 - 0.025 15.1 0.2 0.048 14.2 0.2 1.4 1 0 0 1 1 1 0 Hepatocyte growth factor-regulated tyrosine kinase substrate Tox-SHH PF15652.6 KKK22904.1 - 0.06 14.3 0.1 0.16 12.9 0.1 1.7 1 0 0 1 1 1 0 HNH/Endo VII superfamily toxin with a SHH signature CAF1A PF12253.8 KKK22904.1 - 0.33 11.1 4.7 0.37 11.0 0.1 2.5 3 0 0 3 3 3 0 Chromatin assembly factor 1 subunit A PRP38_assoc PF12871.7 KKK22905.1 - 4.6 7.9 81.5 3 8.5 32.3 3.1 1 1 1 2 2 2 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term SPOC PF07744.13 KKK22906.1 - 3.4e-24 85.5 0.0 5.7e-24 84.8 0.0 1.4 1 0 0 1 1 1 1 SPOC domain TFIIS_M PF07500.14 KKK22906.1 - 8.2e-22 77.8 0.0 1.7e-21 76.8 0.0 1.5 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain PHD PF00628.29 KKK22906.1 - 6e-11 42.1 12.4 1.2e-10 41.1 12.4 1.5 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 KKK22906.1 - 0.12 12.0 4.3 0.23 11.1 4.3 1.5 1 0 0 1 1 1 0 PHD-finger MecA PF05389.12 KKK22906.1 - 0.66 9.6 2.3 10 5.6 2.3 2.6 1 1 0 1 1 1 0 Negative regulator of genetic competence (MecA) PHD_3 PF13922.6 KKK22906.1 - 0.79 10.2 6.6 0.13 12.7 0.4 2.9 2 0 0 2 2 2 0 PHD domain of transcriptional enhancer, Asx TFIIA PF03153.13 KKK22907.1 - 0.024 14.6 18.7 0.031 14.3 18.7 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF932 PF06067.11 KKK22907.1 - 0.24 11.2 8.1 0.055 13.2 0.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF932) Ribosomal_L29 PF00831.23 KKK22907.1 - 3.6 7.6 10.3 0.16 12.0 0.7 3.2 3 0 0 3 3 3 0 Ribosomal L29 protein FF PF01846.19 KKK22908.1 - 4.9e-13 49.0 6.6 3.5e-10 39.9 0.1 3.6 3 0 0 3 3 3 3 FF domain WW PF00397.26 KKK22908.1 - 7.9e-10 38.7 3.1 7.9e-10 38.7 3.1 3.0 3 0 0 3 3 3 2 WW domain DUF4200 PF13863.6 KKK22908.1 - 0.87 10.0 26.4 0.82 10.1 8.5 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4200) Tht1 PF04163.12 KKK22909.1 - 0.0089 14.8 11.2 0.0065 15.3 8.6 1.9 2 1 0 2 2 2 1 Tht1-like nuclear fusion protein Laps PF10169.9 KKK22909.1 - 0.037 14.6 0.6 0.078 13.6 0.6 1.6 1 0 0 1 1 1 0 Learning-associated protein GspH PF12019.8 KKK22909.1 - 0.16 12.4 1.8 0.2 12.1 0.1 2.2 2 0 0 2 2 2 0 Type II transport protein GspH MukF_M PF17192.4 KKK22909.1 - 0.29 10.9 8.3 0.9 9.3 0.7 2.5 2 0 0 2 2 2 0 MukF middle domain Med2 PF11214.8 KKK22909.1 - 0.64 10.2 9.4 2.1 8.5 1.7 3.5 1 1 2 3 3 3 0 Mediator complex subunit 2 Gpi16 PF04113.14 KKK22911.1 - 4.7e-226 751.6 0.0 5.8e-224 744.7 0.0 2.0 1 1 0 1 1 1 1 Gpi16 subunit, GPI transamidase component LUC7 PF03194.15 KKK22912.1 - 7.5e-74 248.6 1.5 8.7e-74 248.4 1.5 1.0 1 0 0 1 1 1 1 LUC7 N_terminus MCPsignal PF00015.21 KKK22912.1 - 0.018 14.8 0.0 0.027 14.3 0.0 1.3 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain TelA PF05816.11 KKK22912.1 - 0.052 12.6 1.6 0.079 12.0 0.5 1.7 2 0 0 2 2 2 0 Toxic anion resistance protein (TelA) HMG_box_5 PF14887.6 KKK22912.1 - 0.089 12.8 0.1 1.2 9.1 0.0 2.3 1 1 1 2 2 2 0 HMG (high mobility group) box 5 PIN_8 PF18476.1 KKK22912.1 - 0.11 12.4 0.1 1.1 9.1 0.0 2.0 2 0 0 2 2 2 0 PIN like domain zinc-ribbons_6 PF07191.12 KKK22912.1 - 0.13 12.3 0.4 0.33 10.9 0.2 1.7 2 0 0 2 2 2 0 zinc-ribbons Snf7 PF03357.21 KKK22912.1 - 0.28 10.8 4.8 0.22 11.1 2.4 2.0 2 1 0 2 2 2 0 Snf7 Occludin_ELL PF07303.13 KKK22912.1 - 0.88 10.3 4.0 1.5 9.6 0.1 2.7 2 1 0 2 2 2 0 Occludin homology domain FAD_binding_1 PF00667.20 KKK22913.1 - 8.8e-63 211.8 0.0 1.6e-62 211.0 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain POR PF01558.18 KKK22913.1 - 1.2e-10 41.8 0.1 5.1e-10 39.7 0.1 2.1 2 0 0 2 2 2 1 Pyruvate ferredoxin/flavodoxin oxidoreductase NAD_binding_1 PF00175.21 KKK22913.1 - 2.5e-09 37.8 0.0 6.2e-09 36.5 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain PFOR_II PF17147.4 KKK22913.1 - 7.1e-07 29.5 0.1 2.3e-06 27.9 0.1 1.8 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II Transketolase_C PF02780.20 KKK22913.1 - 0.00044 20.1 0.1 0.0016 18.3 0.1 2.0 1 0 0 1 1 1 1 Transketolase, C-terminal domain Dfp1_Him1_M PF08630.10 KKK22914.1 - 3.1e-37 127.6 0.0 9.1e-37 126.1 0.0 1.9 1 0 0 1 1 1 1 Dfp1/Him1, central region zf-DBF PF07535.12 KKK22914.1 - 7.5e-21 74.0 0.2 1.4e-20 73.1 0.2 1.5 1 0 0 1 1 1 1 DBF zinc finger Pantoate_transf PF02548.15 KKK22915.1 - 3.1e-109 364.3 1.2 3.7e-109 364.1 1.2 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.6 KKK22915.1 - 1.1e-08 34.8 0.4 2.1e-08 34.0 0.4 1.6 1 1 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Pyridox_ox_2 PF12900.7 KKK22916.1 - 2.1e-38 131.5 0.0 2.9e-38 131.1 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Peptidase_M24 PF00557.24 KKK22917.1 - 1.3e-45 155.7 0.0 2.4e-45 154.8 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 KKK22917.1 - 2.7e-36 124.0 0.0 4.3e-36 123.4 0.0 1.3 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Creatinase_N PF01321.18 KKK22917.1 - 0.1 13.3 0.0 0.51 11.0 0.0 2.1 1 1 0 1 1 1 0 Creatinase/Prolidase N-terminal domain RuBisCO_large PF00016.20 KKK22917.1 - 0.16 11.2 0.0 0.24 10.5 0.0 1.2 1 0 0 1 1 1 0 Ribulose bisphosphate carboxylase large chain, catalytic domain SIR2 PF02146.17 KKK22918.1 - 5.6e-20 72.0 0.0 7.5e-20 71.6 0.0 1.1 1 0 0 1 1 1 1 Sir2 family Flavoprotein PF02441.19 KKK22919.1 - 1.9e-14 53.7 0.0 3e-14 53.1 0.0 1.3 1 0 0 1 1 1 1 Flavoprotein DUF1391 PF07151.12 KKK22919.1 - 0.087 12.7 0.2 0.19 11.6 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1391) SnoaL_2 PF12680.7 KKK22919.1 - 0.16 12.6 0.1 33 5.2 0.0 2.6 1 1 0 2 2 2 0 SnoaL-like domain MFS_1 PF07690.16 KKK22920.1 - 1.7e-44 152.2 43.5 1.7e-44 152.2 43.5 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KKK22920.1 - 3.8e-18 65.6 29.8 4.3e-14 52.2 5.0 3.3 2 1 1 3 3 3 3 Sugar (and other) transporter OATP PF03137.20 KKK22920.1 - 1.5 7.0 12.5 0.023 13.0 2.4 2.5 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family ANAPC4_WD40 PF12894.7 KKK22928.1 - 3.9e-08 33.5 1.5 2.5 8.5 0.0 5.4 3 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KKK22928.1 - 4.3e-07 30.5 12.5 0.063 14.2 0.1 6.8 7 0 0 7 7 7 2 WD domain, G-beta repeat LisH PF08513.11 KKK22928.1 - 1.4e-06 28.1 0.0 2.9e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 LisH eIF2A PF08662.11 KKK22928.1 - 0.00073 19.5 0.0 0.0027 17.6 0.0 2.0 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A APG6_N PF17675.1 KKK22929.1 - 0.00058 20.4 0.7 0.001 19.6 0.7 1.5 1 0 0 1 1 1 1 Apg6 coiled-coil region Spc7 PF08317.11 KKK22929.1 - 0.012 14.5 0.8 0.02 13.8 0.8 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Jnk-SapK_ap_N PF09744.9 KKK22929.1 - 0.014 15.6 5.4 0.014 15.6 5.4 1.8 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 IL2 PF00715.17 KKK22929.1 - 0.025 14.5 0.4 0.047 13.6 0.4 1.4 1 0 0 1 1 1 0 Interleukin 2 PspA_IM30 PF04012.12 KKK22929.1 - 0.058 13.0 3.5 1 8.9 0.1 2.2 1 1 1 2 2 2 0 PspA/IM30 family Baculo_PEP_C PF04513.12 KKK22929.1 - 0.07 13.2 0.5 0.17 11.9 0.1 1.8 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus COMP PF11598.8 KKK22929.1 - 0.2 12.2 2.6 0.27 11.8 0.4 2.2 2 0 0 2 2 2 0 Cartilage oligomeric matrix protein FAD-SLDH PF12318.8 KKK22929.1 - 0.27 11.3 1.9 0.38 10.8 0.4 1.9 2 0 0 2 2 2 0 Membrane bound FAD containing D-sorbitol dehydrogenase TPR_MLP1_2 PF07926.12 KKK22929.1 - 0.44 10.6 7.7 0.83 9.7 7.7 1.4 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein WD40_alt PF14077.6 KKK22929.1 - 0.85 9.5 2.8 0.77 9.7 0.9 1.8 2 0 0 2 2 2 0 Alternative WD40 repeat motif Med21 PF11221.8 KKK22929.1 - 2.5 8.4 9.4 93 3.2 9.4 2.6 1 1 0 1 1 1 0 Subunit 21 of Mediator complex ZapB PF06005.12 KKK22929.1 - 2.9 8.4 9.5 0.35 11.4 4.2 2.2 2 1 0 2 2 1 0 Cell division protein ZapB FlxA PF14282.6 KKK22929.1 - 3.9 7.5 7.7 4.7 7.3 5.8 2.0 1 1 1 2 2 2 0 FlxA-like protein DivIC PF04977.15 KKK22929.1 - 4.5 7.1 5.5 4.7 7.0 2.9 2.2 1 1 1 2 2 2 0 Septum formation initiator BST2 PF16716.5 KKK22929.1 - 9.8 6.8 7.8 11 6.7 0.2 2.8 3 0 0 3 3 3 0 Bone marrow stromal antigen 2 Chorismate_bind PF00425.18 KKK22930.1 - 1e-90 303.8 0.0 1.5e-90 303.2 0.0 1.3 1 0 0 1 1 1 1 chorismate binding enzyme Anth_synt_I_N PF04715.13 KKK22930.1 - 5.5e-27 94.7 0.0 2.9e-24 85.9 0.0 3.2 3 1 0 3 3 3 2 Anthranilate synthase component I, N terminal region DUF1751 PF08551.10 KKK22931.1 - 1e-22 80.5 3.0 3.9e-22 78.7 1.9 2.5 2 1 0 2 2 2 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.22 KKK22931.1 - 7.3e-05 22.8 6.2 0.00075 19.5 6.2 2.1 1 1 0 1 1 1 1 Rhomboid family DUF4149 PF13664.6 KKK22931.1 - 1.2 9.5 6.8 0.68 10.3 1.8 2.7 1 1 1 3 3 3 0 Domain of unknown function (DUF4149) L51_S25_CI-B8 PF05047.16 KKK22932.1 - 1.6e-20 72.7 0.0 2.5e-20 72.1 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain DUF1382 PF07131.11 KKK22932.1 - 0.6 10.2 3.5 4.8 7.3 1.7 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1382) tRNA-synt_1 PF00133.22 KKK22933.1 - 9.9e-37 126.5 0.0 2.2e-25 89.0 0.0 2.8 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 KKK22933.1 - 5.4e-17 61.6 0.0 3.7e-10 39.1 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 KKK22933.1 - 6.5e-15 55.4 0.2 1.6e-14 54.2 0.2 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 KKK22933.1 - 1.5e-07 31.1 0.0 3.6e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1b PF00579.25 KKK22933.1 - 0.24 10.7 1.4 1.9 7.7 0.0 2.5 2 1 1 3 3 3 0 tRNA synthetases class I (W and Y) MMR_HSR1 PF01926.23 KKK22934.1 - 1.4e-05 25.1 0.0 0.0015 18.6 0.0 2.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase ATPase-cat_bd PF12156.8 KKK22934.1 - 0.0022 18.7 0.2 0.0057 17.4 0.2 1.6 1 0 0 1 1 1 1 Putative metal-binding domain of cation transport ATPase RsgA_GTPase PF03193.16 KKK22934.1 - 0.0092 15.9 0.2 0.024 14.5 0.0 1.8 2 0 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 KKK22934.1 - 0.013 15.5 0.0 3.5 7.6 0.2 2.9 1 1 1 2 2 2 0 Dynamin family Mrpl_C PF18502.1 KKK22934.1 - 0.13 12.5 0.2 9.1 6.6 0.1 2.7 2 0 0 2 2 2 0 54S ribosomal protein L8 C-terminal domain Sde2_N_Ubi PF13019.6 KKK22935.1 - 6.8e-69 230.9 0.3 1.2e-68 230.1 0.3 1.4 1 0 0 1 1 1 1 Silencing defective 2 N-terminal ubiquitin domain Rotamase_2 PF13145.6 KKK22935.1 - 0.039 14.8 1.6 0.075 13.9 1.6 1.4 1 0 0 1 1 1 0 PPIC-type PPIASE domain S10_plectin PF03501.15 KKK22936.1 - 4.6e-42 142.0 0.1 6.9e-42 141.4 0.1 1.2 1 0 0 1 1 1 1 Plectin/S10 domain tRNA-synt_1c_C PF03950.18 KKK22936.1 - 0.055 13.3 0.0 0.07 13.0 0.0 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (E and Q), anti-codon binding domain Peptidase_M20 PF01546.28 KKK22937.1 - 4.2e-28 98.4 0.1 5.4e-28 98.1 0.1 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KKK22937.1 - 0.00038 20.3 0.0 0.0007 19.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KKK22937.1 - 0.041 13.6 0.0 1.2 8.8 0.0 2.2 2 0 0 2 2 2 0 Peptidase family M28 HIT PF01230.23 KKK22938.1 - 1.8e-22 79.9 0.2 2.4e-22 79.5 0.2 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 KKK22938.1 - 3.6e-13 50.0 0.0 5.3e-13 49.4 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 KKK22938.1 - 3.8e-05 23.5 0.0 5.3e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 Fungal_trans_2 PF11951.8 KKK22939.1 - 2.9e-11 42.8 0.0 8.1e-11 41.4 0.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK22939.1 - 7.8e-09 35.5 7.8 1.5e-08 34.6 7.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NADH-u_ox-rdase PF10785.9 KKK22952.1 - 1.3e-30 105.8 0.1 2.5e-30 105.0 0.1 1.4 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit NADH_u_ox_C PF12853.7 KKK22952.1 - 1.8e-25 88.8 0.1 2.5e-25 88.3 0.1 1.2 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit Ras PF00071.22 KKK22953.1 - 3.1e-65 218.7 0.1 3.6e-65 218.5 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KKK22953.1 - 4.9e-34 117.1 0.0 7.2e-34 116.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKK22953.1 - 8e-14 51.5 0.1 1e-13 51.1 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KKK22953.1 - 3.1e-06 26.9 0.0 7.8e-06 25.6 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KKK22953.1 - 0.00011 21.6 0.0 0.00013 21.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 KKK22953.1 - 0.00042 20.2 0.2 0.43 10.5 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 KKK22953.1 - 0.0049 16.9 0.0 0.007 16.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KKK22953.1 - 0.016 14.8 0.0 0.076 12.5 0.0 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B SRPRB PF09439.10 KKK22953.1 - 0.031 13.7 0.0 0.037 13.5 0.0 1.1 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA PF00004.29 KKK22953.1 - 0.049 14.1 0.0 8.2 6.9 0.0 2.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KKK22953.1 - 0.16 12.3 0.0 0.49 10.7 0.0 2.0 1 1 0 1 1 1 0 AAA domain NCA2 PF08637.10 KKK22954.1 - 8.8e-93 310.6 0.0 1.4e-92 309.9 0.0 1.3 1 0 0 1 1 1 1 ATP synthase regulation protein NCA2 FA_hydroxylase PF04116.13 KKK22955.1 - 4e-25 88.7 16.9 4e-25 88.7 16.9 2.0 2 1 1 3 3 3 1 Fatty acid hydroxylase superfamily dCMP_cyt_deam_1 PF00383.23 KKK22956.1 - 1.7e-25 88.8 0.0 2.2e-25 88.4 0.0 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KKK22956.1 - 4.8e-21 75.0 0.0 7e-21 74.4 0.0 1.1 1 0 0 1 1 1 1 MafB19-like deaminase XOO_2897-deam PF14440.6 KKK22956.1 - 0.0011 19.0 0.0 0.0022 18.1 0.0 1.5 1 0 0 1 1 1 1 Xanthomonas XOO_2897-like deaminase APOBEC4_like PF18774.1 KKK22956.1 - 0.0027 17.7 0.0 0.0043 17.0 0.0 1.3 1 0 0 1 1 1 1 APOBEC4-like -AID/APOBEC-deaminase SNAD4 PF18750.1 KKK22956.1 - 0.009 16.1 0.0 0.016 15.3 0.0 1.4 1 0 0 1 1 1 1 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC3 PF18771.1 KKK22956.1 - 0.03 14.4 0.0 0.047 13.8 0.0 1.3 1 0 0 1 1 1 0 APOBEC3 APOBEC2 PF18772.1 KKK22956.1 - 0.049 13.7 0.0 0.064 13.3 0.0 1.2 1 0 0 1 1 1 0 APOBEC2 NAD1 PF18778.1 KKK22956.1 - 0.052 13.6 0.0 0.071 13.2 0.0 1.2 1 0 0 1 1 1 0 Novel AID APOBEC clade 1 APOBEC_N PF08210.11 KKK22956.1 - 0.053 13.4 0.0 0.079 12.8 0.0 1.2 1 0 0 1 1 1 0 APOBEC-like N-terminal domain Bd3614-deam PF14439.6 KKK22956.1 - 0.12 12.4 0.9 0.51 10.4 0.9 1.9 1 1 0 1 1 1 0 Bd3614-like deaminase PI3_PI4_kinase PF00454.27 KKK22957.1 - 1.7e-55 188.6 0.0 3.6e-55 187.5 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 KKK22957.1 - 5.1e-45 154.2 2.5 1.1e-44 153.1 2.5 1.6 1 0 0 1 1 1 1 FAT domain UME PF08064.13 KKK22957.1 - 2.8e-34 117.1 0.2 3.1e-33 113.7 0.3 2.9 2 0 0 2 2 2 1 UME (NUC010) domain FATC PF02260.20 KKK22957.1 - 1.2e-12 47.4 0.0 3.3e-12 46.0 0.0 1.8 1 0 0 1 1 1 1 FATC domain TPR_7 PF13176.6 KKK22957.1 - 0.014 15.4 0.6 13 6.1 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF3385 PF11865.8 KKK22957.1 - 0.06 13.3 0.1 0.29 11.0 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3385) TPR_19 PF14559.6 KKK22957.1 - 0.07 13.6 0.5 11 6.6 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat BTAD PF03704.17 KKK22957.1 - 0.093 13.2 4.3 0.5 10.8 0.0 3.3 3 0 0 3 3 3 0 Bacterial transcriptional activator domain TPR_14 PF13428.6 KKK22957.1 - 0.32 11.9 5.2 30 5.8 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat RRM_1 PF00076.22 KKK22958.1 - 7.1e-15 54.6 0.0 1.1e-14 54.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KKK22958.1 - 0.066 12.8 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KKK22958.1 - 0.073 13.1 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 RNA binding motif Corona_nucleoca PF00937.18 KKK22958.1 - 0.092 11.8 9.5 0.16 11.0 9.5 1.4 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein PetN PF03742.14 KKK22958.1 - 0.094 12.6 0.7 0.28 11.1 0.7 1.7 1 0 0 1 1 1 0 PetN AAA PF00004.29 KKK22959.1 - 3.1e-62 208.8 0.0 1.3e-41 142.1 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KKK22959.1 - 1.1e-17 63.5 1.8 6.6e-12 45.0 1.3 3.2 2 1 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 KKK22959.1 - 3.6e-11 43.7 1.2 0.014 15.8 0.2 4.7 2 2 2 4 4 4 2 AAA ATPase domain AAA_5 PF07728.14 KKK22959.1 - 1e-06 28.8 1.3 0.0039 17.2 0.1 3.3 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) Rad17 PF03215.15 KKK22959.1 - 9.5e-06 25.7 0.0 0.00016 21.7 0.0 2.4 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_7 PF12775.7 KKK22959.1 - 2.4e-05 23.9 0.1 0.23 10.9 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_28 PF13521.6 KKK22959.1 - 3.9e-05 24.0 0.2 0.3 11.3 0.0 2.9 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.6 KKK22959.1 - 5.3e-05 23.5 3.5 1.3 9.3 0.1 4.7 2 2 1 4 4 4 2 AAA domain RuvB_N PF05496.12 KKK22959.1 - 8.9e-05 22.3 0.0 0.016 14.9 0.0 3.5 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 KKK22959.1 - 0.00017 20.9 0.1 0.011 15.0 0.0 2.5 3 0 0 3 3 3 1 TIP49 P-loop domain RNA_helicase PF00910.22 KKK22959.1 - 0.00019 21.8 0.0 0.51 10.8 0.0 2.8 2 1 0 2 2 2 2 RNA helicase AAA_14 PF13173.6 KKK22959.1 - 0.00076 19.5 0.0 0.64 10.0 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_2 PF07724.14 KKK22959.1 - 0.00079 19.6 0.0 0.003 17.7 0.0 2.0 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) ATPase_2 PF01637.18 KKK22959.1 - 0.0015 18.5 0.2 0.5 10.2 0.0 3.3 2 1 1 3 3 3 1 ATPase domain predominantly from Archaea DUF815 PF05673.13 KKK22959.1 - 0.0022 17.2 0.0 1.8 7.6 0.0 2.6 3 0 0 3 3 3 2 Protein of unknown function (DUF815) IstB_IS21 PF01695.17 KKK22959.1 - 0.0039 16.9 0.0 2.7 7.7 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_24 PF13479.6 KKK22959.1 - 0.013 15.2 0.0 1.1 8.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 KKK22959.1 - 0.014 15.0 3.2 12 5.5 0.0 3.9 2 2 1 3 3 3 0 AAA domain AAA_11 PF13086.6 KKK22959.1 - 0.015 15.1 0.0 1.6 8.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain Vps4_C PF09336.10 KKK22959.1 - 0.023 14.7 0.1 1.1 9.3 0.0 2.8 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain AAA_29 PF13555.6 KKK22959.1 - 0.048 13.4 0.1 0.19 11.5 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_30 PF13604.6 KKK22959.1 - 0.061 13.0 0.2 2.5 7.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 KKK22959.1 - 0.12 11.7 0.5 2.7 7.3 0.0 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI TsaE PF02367.17 KKK22959.1 - 0.14 12.2 0.0 14 5.7 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE TniB PF05621.11 KKK22959.1 - 0.16 11.4 0.0 20 4.5 0.0 3.0 2 1 1 3 3 3 0 Bacterial TniB protein Adeno_IVa2 PF02456.15 KKK22959.1 - 0.16 10.8 0.2 6.6 5.4 0.0 2.2 2 0 0 2 2 2 0 Adenovirus IVa2 protein AAA_18 PF13238.6 KKK22959.1 - 0.17 12.5 0.1 39 4.8 0.0 2.8 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KKK22959.1 - 0.24 11.3 1.0 10 6.0 0.2 3.5 2 2 0 3 3 3 0 NACHT domain Swi3 PF07962.12 KKK22960.1 - 1.3e-33 114.9 0.4 2.7e-33 113.8 0.4 1.6 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 Menin PF05053.13 KKK22960.1 - 1.1 7.5 4.2 1.6 7.0 4.2 1.1 1 0 0 1 1 1 0 Menin E1_dh PF00676.20 KKK22961.1 - 2.3e-114 381.4 0.1 2.8e-114 381.1 0.1 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 KKK22961.1 - 0.00046 19.5 0.1 0.00086 18.6 0.1 1.4 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase OTU PF02338.19 KKK22962.1 - 5e-08 33.5 0.0 1.7e-07 31.7 0.0 1.8 1 1 0 1 1 1 1 OTU-like cysteine protease CUE PF02845.16 KKK22962.1 - 0.017 14.8 0.0 0.049 13.3 0.0 1.8 1 0 0 1 1 1 0 CUE domain STIL_N PF15253.6 KKK22962.1 - 0.14 11.0 0.6 0.24 10.3 0.6 1.2 1 0 0 1 1 1 0 SCL-interrupting locus protein N-terminus MHYT PF03707.16 KKK22963.1 - 2.2e-19 69.3 23.3 5.2e-09 36.1 1.9 4.5 4 0 0 4 4 4 3 Bacterial signalling protein N terminal repeat DUF4131 PF13567.6 KKK22963.1 - 1.5 8.4 6.6 0.23 11.1 1.2 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) Pyridoxal_deC PF00282.19 KKK22965.1 - 1.5e-80 270.7 0.0 1.9e-80 270.4 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 KKK22965.1 - 4.5e-05 22.6 0.0 6.8e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Abhydrolase_1 PF00561.20 KKK22972.1 - 3.8e-12 46.4 0.1 4e-11 43.1 0.1 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KKK22972.1 - 1.7e-08 34.0 0.0 1.4e-07 31.0 0.0 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Cohesin_load PF10345.9 KKK22974.1 - 9.3e-185 615.5 8.4 1.1e-184 615.3 8.4 1.0 1 0 0 1 1 1 1 Cohesin loading factor F-box_4 PF15966.5 KKK22974.1 - 0.035 14.0 0.2 0.13 12.1 0.2 2.1 1 0 0 1 1 1 0 F-box F-box PF00646.33 KKK22974.1 - 0.068 13.1 1.6 0.15 12.0 1.6 1.6 1 0 0 1 1 1 0 F-box domain HTH_WhiA PF02650.14 KKK22974.1 - 0.15 12.4 1.5 0.27 11.6 0.3 2.0 2 0 0 2 2 2 0 WhiA C-terminal HTH domain F-box-like PF12937.7 KKK22974.1 - 0.28 11.1 6.5 0.034 14.0 1.5 2.1 2 0 0 2 2 2 0 F-box-like TPR_12 PF13424.6 KKK22974.1 - 0.41 11.0 13.4 0.13 12.5 1.1 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 KKK22974.1 - 2.5 8.8 5.4 20 5.9 0.3 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat RRP36 PF06102.12 KKK22975.1 - 3.4e-49 167.0 21.1 3.4e-49 167.0 21.1 2.1 2 0 0 2 2 2 1 rRNA biogenesis protein RRP36 NIF PF03031.18 KKK22977.1 - 7.4e-27 94.0 0.0 1.4e-26 93.2 0.0 1.5 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase K_channel_TID PF07941.11 KKK22977.1 - 8 7.0 9.2 18 5.9 9.2 1.5 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain RNA_pol_L_2 PF13656.6 KKK22978.1 - 1.7e-33 114.2 0.0 2.3e-33 113.8 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 KKK22978.1 - 3.2e-15 55.3 0.0 6.5e-15 54.3 0.0 1.5 2 0 0 2 2 2 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Vta1_C PF18097.1 KKK22978.1 - 0.11 12.2 0.1 0.24 11.2 0.1 1.6 1 0 0 1 1 1 0 Vta1 C-terminal domain Complex1_LYR_2 PF13233.6 KKK22979.1 - 1.6e-06 28.8 0.7 2.8e-06 28.0 0.7 1.4 1 1 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 KKK22979.1 - 1.6e-05 24.9 0.5 3e-05 24.0 0.5 1.5 1 1 0 1 1 1 1 Complex 1 protein (LYR family) IKKbetaNEMObind PF12179.8 KKK22979.1 - 0.082 13.0 0.0 0.78 9.8 0.0 2.2 2 0 0 2 2 2 0 I-kappa-kinase-beta NEMO binding domain Arb1 PF09692.10 KKK22982.1 - 5.4e-126 421.0 0.0 6.3e-126 420.8 0.0 1.0 1 0 0 1 1 1 1 Argonaute siRNA chaperone (ARC) complex subunit Arb1 DUF600 PF04634.12 KKK22982.1 - 0.00073 19.6 0.0 0.0014 18.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF600 IPK PF03770.16 KKK22983.1 - 2.8e-60 203.6 0.0 4e-60 203.1 0.0 1.2 1 0 0 1 1 1 1 Inositol polyphosphate kinase TPPII_N PF12583.8 KKK22983.1 - 3.4 8.3 12.1 7.4 7.2 11.4 1.8 2 0 0 2 2 2 0 Tripeptidyl peptidase II N terminal SBF PF01758.16 KKK22984.1 - 5.3e-49 166.5 7.4 5.3e-49 166.5 7.4 2.4 2 2 1 3 3 3 1 Sodium Bile acid symporter family LMWPc PF01451.21 KKK22985.1 - 2.4e-21 76.6 0.0 3.3e-21 76.1 0.0 1.2 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase FMN_red PF03358.15 KKK22986.1 - 2.2e-22 79.5 0.0 3.3e-22 78.9 0.0 1.3 1 0 0 1 1 1 1 NADPH-dependent FMN reductase OPT PF03169.15 KKK22987.1 - 2.8e-117 392.9 41.3 3.2e-117 392.7 41.3 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein ADH_zinc_N PF00107.26 KKK22988.1 - 1.5e-26 92.9 0.0 3.2e-26 91.9 0.0 1.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KKK22988.1 - 8.6e-23 81.9 0.0 1.6e-22 81.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KKK22988.1 - 5.4e-09 35.9 0.0 2.1e-08 34.0 0.0 1.8 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 KKK22988.1 - 0.00022 21.1 0.0 0.00054 19.8 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase Cpn10 PF00166.21 KKK22988.1 - 0.018 15.1 0.0 0.21 11.7 0.0 2.5 2 0 0 2 2 2 0 Chaperonin 10 Kd subunit CLP1_N PF16573.5 KKK22990.1 - 2.4e-33 114.2 0.0 4.6e-33 113.3 0.0 1.5 1 0 0 1 1 1 1 N-terminal beta-sandwich domain of polyadenylation factor CLP1_P PF16575.5 KKK22990.1 - 3.5e-29 101.9 0.0 2.4e-28 99.2 0.0 2.4 1 1 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop Polysacc_deac_1 PF01522.21 KKK22990.1 - 2e-19 69.7 0.0 1.6e-18 66.8 0.0 2.1 2 0 0 2 2 2 1 Polysaccharide deacetylase Clp1 PF06807.14 KKK22990.1 - 7.1e-16 58.7 0.0 3.1e-15 56.6 0.0 2.1 1 1 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 ATP_bind_1 PF03029.17 KKK22990.1 - 9e-05 22.4 0.0 0.0003 20.7 0.0 1.8 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.23 KKK22990.1 - 0.002 18.2 0.0 0.01 15.9 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_35 PF14516.6 KKK22990.1 - 0.03 13.2 0.0 0.048 12.5 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain KilA-N PF04383.13 KKK22991.1 - 0.00039 20.2 0.0 0.0038 17.1 0.0 2.3 1 1 0 1 1 1 1 KilA-N domain Rho_GDI PF02115.17 KKK22992.1 - 1.6e-39 135.7 0.0 1.9e-39 135.5 0.0 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor SF3b10 PF07189.11 KKK22993.1 - 2.1e-35 120.7 0.0 2.3e-35 120.5 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) A_deamin PF02137.18 KKK22994.1 - 4.8e-24 85.4 0.0 1.4e-20 74.1 0.0 2.9 2 1 0 2 2 2 2 Adenosine-deaminase (editase) domain NT-C2 PF10358.9 KKK22995.1 - 3.5e-36 124.1 0.0 6.3e-36 123.3 0.0 1.5 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins SLS PF14611.6 KKK22995.1 - 7.8e-36 124.0 0.1 2.5e-35 122.3 0.0 1.9 2 0 0 2 2 2 1 Mitochondrial inner-membrane-bound regulator TetR_C_15 PF17918.1 KKK22995.1 - 0.0021 18.8 0.1 0.024 15.4 0.0 2.4 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain Ecl1 PF12855.7 KKK22996.1 - 1.2 10.3 7.2 2.5 9.2 7.2 1.5 1 0 0 1 1 1 0 ECL1/2/3 zinc binding proteins DUF3074 PF11274.8 KKK22997.1 - 9.4e-54 182.2 0.3 9.4e-54 182.2 0.3 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3074) APG6_N PF17675.1 KKK22998.1 - 0.0047 17.5 2.7 0.0056 17.2 2.7 1.1 1 0 0 1 1 1 1 Apg6 coiled-coil region UPF0242 PF06785.11 KKK22998.1 - 0.022 14.8 2.6 0.026 14.6 2.6 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Jnk-SapK_ap_N PF09744.9 KKK22998.1 - 0.033 14.4 6.5 0.042 14.1 6.5 1.1 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Exonuc_VII_L PF02601.15 KKK22998.1 - 0.038 13.6 0.6 0.04 13.5 0.6 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit YaiA PF16362.5 KKK22998.1 - 0.06 13.5 0.7 0.06 13.5 0.7 1.9 2 0 0 2 2 2 0 YaiA protein She9_MDM33 PF05546.11 KKK22998.1 - 0.1 12.4 4.0 0.14 12.0 4.0 1.1 1 0 0 1 1 1 0 She9 / Mdm33 family DinB PF05163.12 KKK22998.1 - 0.11 12.4 0.9 0.14 12.1 0.9 1.1 1 0 0 1 1 1 0 DinB family YojJ PF10372.9 KKK22998.1 - 0.4 10.8 2.6 0.82 9.8 1.5 1.9 1 1 1 2 2 2 0 Bacterial membrane-spanning protein N-terminus TMPIT PF07851.13 KKK22998.1 - 1.1 8.5 3.5 1.4 8.1 3.5 1.0 1 0 0 1 1 1 0 TMPIT-like protein Stathmin PF00836.19 KKK22998.1 - 1.7 8.6 13.8 0.15 12.0 8.6 1.8 2 0 0 2 2 2 0 Stathmin family PAH PF02671.21 KKK22999.1 - 4.2e-08 33.2 2.2 4.9 7.4 0.2 9.4 8 2 0 8 8 8 2 Paired amphipathic helix repeat NUC130_3NT PF08158.12 KKK22999.1 - 0.00078 19.7 14.6 22 5.4 0.1 9.1 9 1 0 10 10 10 1 NUC130/3NT domain EcoEI_R_C PF08463.10 KKK22999.1 - 0.0039 17.3 0.1 15 5.7 0.2 4.9 3 1 4 7 7 7 1 EcoEI R protein C-terminal DUF2357 PF09823.9 KKK22999.1 - 0.11 11.7 0.0 11 5.1 0.0 3.7 4 1 1 5 5 5 0 Domain of unknown function (DUF2357) RP853 PF17542.2 KKK22999.1 - 0.17 11.0 0.6 2.5 7.1 0.1 2.9 2 1 1 3 3 3 0 Uncharacterized RP853 SOG2 PF10428.9 KKK22999.1 - 0.19 10.9 8.8 0.37 9.9 8.8 1.5 1 0 0 1 1 1 0 RAM signalling pathway protein Glyco_hydro_3_C PF01915.22 KKK23000.1 - 2.9e-49 167.8 0.0 5.7e-49 166.9 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KKK23000.1 - 7.1e-38 130.8 0.0 1.4e-37 129.7 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KKK23000.1 - 3.3e-15 55.9 0.1 6.5e-15 55.0 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain bZIP_1 PF00170.21 KKK23001.1 - 0.006 16.7 10.7 0.034 14.2 10.7 1.9 1 1 1 2 2 2 1 bZIP transcription factor Scs3p PF10261.9 KKK23003.1 - 4.8e-60 203.1 11.9 6.1e-60 202.8 7.3 2.7 2 1 0 2 2 2 1 Inositol phospholipid synthesis and fat-storage-inducing TM Man-6-P_recep PF02157.15 KKK23004.1 - 2.1e-17 63.1 0.0 2.9e-17 62.6 0.0 1.1 1 0 0 1 1 1 1 Mannose-6-phosphate receptor ATG27 PF09451.10 KKK23004.1 - 1.1e-10 41.9 0.0 4.5e-10 39.8 0.0 1.7 1 1 0 1 1 1 1 Autophagy-related protein 27 CIMR PF00878.18 KKK23004.1 - 7.5e-08 32.6 1.1 0.00018 21.6 0.1 2.4 2 1 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat ERG4_ERG24 PF01222.17 KKK23005.1 - 1.1e-156 521.9 4.6 1.3e-156 521.7 4.6 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 KKK23005.1 - 6e-07 29.2 0.2 1.5e-06 27.9 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Fungal_trans PF04082.18 KKK23007.1 - 2.7e-26 92.2 0.0 4.8e-26 91.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK23007.1 - 4.7e-09 36.2 12.1 7.4e-09 35.6 12.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_4 PF01565.23 KKK23008.1 - 2.8e-25 88.7 1.5 5.7e-25 87.7 1.5 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KKK23008.1 - 1.7e-06 28.0 1.9 3.1e-06 27.2 0.7 2.1 2 0 0 2 2 2 1 Berberine and berberine like AAA_14 PF13173.6 KKK23009.1 - 0.005 16.9 0.0 0.012 15.7 0.0 1.6 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 KKK23009.1 - 0.043 12.9 0.0 0.082 11.9 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_16 PF13191.6 KKK23009.1 - 0.064 13.6 0.0 0.19 12.1 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain Peptidase_M29 PF02073.15 KKK23010.1 - 0.21 10.3 0.0 0.32 9.7 0.0 1.2 1 0 0 1 1 1 0 Thermophilic metalloprotease (M29) HSP70 PF00012.20 KKK23013.1 - 1.2e-243 809.7 12.6 1.4e-243 809.5 12.6 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KKK23013.1 - 3.2e-17 62.4 2.0 4e-16 58.8 0.7 2.1 2 0 0 2 2 2 1 MreB/Mbl protein DUF1464 PF07318.12 KKK23013.1 - 0.0031 16.7 1.1 0.41 9.8 0.1 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1464) DDR PF08841.10 KKK23013.1 - 0.0045 16.0 0.4 0.013 14.5 0.2 1.8 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain Radial_spoke_3 PF06098.11 KKK23013.1 - 0.11 11.8 3.0 0.048 12.9 0.6 1.6 2 0 0 2 2 2 0 Radial spoke protein 3 Hydantoinase_A PF01968.18 KKK23013.1 - 0.13 11.5 4.6 0.31 10.3 0.1 2.8 3 0 0 3 3 3 0 Hydantoinase/oxoprolinase FIVAR PF07554.13 KKK23013.1 - 0.34 11.7 7.2 16 6.3 2.2 3.9 3 1 0 3 3 3 0 FIVAR domain FtsA PF14450.6 KKK23013.1 - 3.3 8.2 7.4 17 5.9 0.2 3.5 3 2 0 3 3 3 0 Cell division protein FtsA GTP_EFTU PF00009.27 KKK23014.1 - 5.1e-50 169.7 0.1 7.9e-50 169.1 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain HBS1_N PF08938.10 KKK23014.1 - 2.4e-16 59.8 3.5 5.3e-16 58.7 3.5 1.5 1 0 0 1 1 1 1 HBS1 N-terminus MMR_HSR1 PF01926.23 KKK23014.1 - 3.5e-08 33.5 0.0 1.4e-06 28.3 0.0 2.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D3 PF03143.17 KKK23014.1 - 5e-08 33.2 0.0 1.9e-07 31.3 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 KKK23014.1 - 2.2e-06 28.0 0.0 6.6e-06 26.4 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Gtr1_RagA PF04670.12 KKK23014.1 - 0.00025 20.5 0.1 0.00061 19.2 0.1 1.6 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 KKK23014.1 - 0.00045 19.7 0.1 0.13 11.7 0.0 2.5 1 1 1 2 2 2 2 Signal recognition particle receptor beta subunit Arf PF00025.21 KKK23014.1 - 0.0056 16.2 0.2 1.8 7.9 0.0 2.4 1 1 1 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 KKK23014.1 - 0.011 15.9 0.1 2.7 8.2 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase FeoB_N PF02421.18 KKK23014.1 - 0.042 13.4 0.7 1.4 8.4 0.4 2.9 2 1 0 2 2 2 0 Ferrous iron transport protein B Septin PF00735.18 KKK23014.1 - 0.062 12.6 0.0 0.12 11.6 0.0 1.5 1 0 0 1 1 1 0 Septin Acyltransf_C PF16076.5 KKK23014.1 - 0.12 12.4 0.0 0.3 11.2 0.0 1.7 1 0 0 1 1 1 0 Acyltransferase C-terminus Mannosyl_trans2 PF04188.13 KKK23025.1 - 6.6e-52 177.3 22.7 8.2e-52 177.0 22.7 1.1 1 0 0 1 1 1 1 Mannosyltransferase (PIG-V) Pro_CA PF00484.19 KKK23027.1 - 2.4e-29 102.6 1.5 5.6e-23 81.9 0.5 2.1 1 1 1 2 2 2 2 Carbonic anhydrase GGACT PF06094.12 KKK23027.1 - 0.073 13.7 0.0 0.13 12.8 0.0 1.4 1 0 0 1 1 1 0 Gamma-glutamyl cyclotransferase, AIG2-like AMP-binding PF00501.28 KKK23028.1 - 3.4e-67 226.9 0.0 5.5e-67 226.2 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 KKK23028.1 - 8e-59 198.9 0.0 2.2e-48 164.7 0.0 2.3 1 1 1 2 2 2 2 Male sterility protein Epimerase PF01370.21 KKK23028.1 - 8.4e-15 54.9 0.0 3e-14 53.1 0.0 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Condensation PF00668.20 KKK23028.1 - 7.8e-12 44.6 0.0 4.8e-11 42.0 0.0 1.9 1 1 0 1 1 1 1 Condensation domain PP-binding PF00550.25 KKK23028.1 - 9e-09 35.6 0.0 2e-08 34.4 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.19 KKK23028.1 - 4.5e-05 22.6 0.0 0.00013 21.0 0.0 1.8 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KKK23028.1 - 4.9e-05 23.3 0.0 0.00012 22.0 0.0 1.8 1 1 0 1 1 1 1 NAD(P)H-binding AMP-binding_C PF13193.6 KKK23028.1 - 0.0035 18.3 0.0 0.016 16.1 0.0 2.3 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain RmlD_sub_bind PF04321.17 KKK23028.1 - 0.0058 15.8 0.1 0.034 13.2 0.1 2.1 1 1 0 1 1 1 1 RmlD substrate binding domain ECH_1 PF00378.20 KKK23029.1 - 1.3e-49 168.8 0.0 1.5e-49 168.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KKK23029.1 - 3.2e-20 72.9 0.0 1.3e-14 54.5 0.0 2.5 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Condensation PF00668.20 KKK23030.1 - 1.6e-77 261.1 0.0 5.2e-38 130.9 0.0 2.7 2 0 0 2 2 2 2 Condensation domain AMP-binding PF00501.28 KKK23030.1 - 9.4e-71 238.6 0.0 1.5e-65 221.4 0.0 2.5 2 0 0 2 2 2 2 AMP-binding enzyme PP-binding PF00550.25 KKK23030.1 - 3.5e-28 97.8 0.1 1.4e-12 47.8 0.1 3.1 2 0 0 2 2 2 2 Phosphopantetheine attachment site WES_acyltransf PF03007.16 KKK23030.1 - 0.016 15.0 0.0 0.26 11.0 0.0 2.5 2 0 0 2 2 2 0 Wax ester synthase-like Acyl-CoA acyltransferase domain AMP-binding_C PF13193.6 KKK23030.1 - 0.033 15.1 0.2 30 5.7 0.0 3.3 3 0 0 3 3 3 0 AMP-binding enzyme C-terminal domain DUF433 PF04255.14 KKK23030.1 - 0.058 13.3 0.0 6.2 6.8 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF433) Myb_DNA-bind_6 PF13921.6 KKK23038.1 - 0.00079 19.6 0.3 0.0014 18.9 0.3 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain COesterase PF00135.28 KKK23039.1 - 3.7e-85 286.7 0.0 4.9e-85 286.3 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KKK23039.1 - 3.3e-07 30.4 0.3 2.1e-06 27.8 0.2 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KKK23039.1 - 1.5e-06 27.9 0.1 2.3e-06 27.3 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Alph_Pro_TM PF09608.10 KKK23040.1 - 0.025 14.4 1.8 0.036 13.9 1.8 1.1 1 0 0 1 1 1 0 Putative transmembrane protein (Alph_Pro_TM) Spt20 PF12090.8 KKK23040.1 - 5.2 6.6 23.1 8.5 5.9 23.1 1.3 1 0 0 1 1 1 0 Spt20 family DUF4187 PF13821.6 KKK23041.1 - 1.7e-22 78.9 3.5 1.7e-22 78.9 3.5 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4187) G-patch PF01585.23 KKK23041.1 - 3.9e-08 33.1 0.3 1.5e-05 24.8 0.2 2.5 2 0 0 2 2 2 2 G-patch domain DUF4615 PF15393.6 KKK23041.1 - 0.75 10.4 10.7 0.14 12.8 4.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4615) BNR_2 PF13088.6 KKK23046.1 - 2.1e-07 30.6 0.0 8.8e-05 21.9 0.0 3.2 1 1 2 3 3 3 2 BNR repeat-like domain BNR PF02012.20 KKK23046.1 - 0.00078 19.1 15.2 0.48 10.6 0.2 5.1 5 0 0 5 5 5 3 BNR/Asp-box repeat Sortilin-Vps10 PF15902.5 KKK23046.1 - 0.09 11.5 0.1 3 6.5 0.0 2.5 2 1 0 2 2 2 0 Sortilin, neurotensin receptor 3, DUF3128 PF11326.8 KKK23047.1 - 0.15 12.5 2.6 1.1 9.7 0.4 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3128) Pkinase PF00069.25 KKK23061.1 - 5.5e-49 166.9 0.0 8e-49 166.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK23061.1 - 1.3e-25 90.1 0.0 2e-25 89.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KKK23061.1 - 0.0031 16.9 0.0 0.0056 16.1 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KKK23061.1 - 0.0095 14.9 0.0 0.014 14.4 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KKK23061.1 - 0.035 13.4 0.0 0.55 9.5 0.0 2.1 1 1 0 2 2 2 0 Kinase-like APH PF01636.23 KKK23061.1 - 0.069 13.1 0.0 0.069 13.1 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family Radial_spoke_3 PF06098.11 KKK23061.1 - 0.51 9.6 6.5 0.91 8.7 6.5 1.4 1 0 0 1 1 1 0 Radial spoke protein 3 Rrn6 PF10214.9 KKK23061.1 - 8.3 4.8 10.8 11 4.4 10.8 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor HMA PF00403.26 KKK23062.1 - 1.6e-13 50.9 0.0 3.2e-13 49.9 0.0 1.5 1 0 0 1 1 1 1 Heavy-metal-associated domain Sod_Cu PF00080.20 KKK23062.1 - 1.9e-08 34.6 0.0 3.2e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Aminotran_1_2 PF00155.21 KKK23063.1 - 4.5e-73 246.5 0.0 5.5e-73 246.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II TPR_1 PF00515.28 KKK23064.1 - 5.3e-13 48.2 6.0 5.3e-06 26.0 0.0 4.6 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 KKK23064.1 - 9.9e-12 44.0 4.9 0.00039 20.3 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 KKK23064.1 - 1.6e-08 34.7 0.0 3.6e-05 24.0 0.0 3.2 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 KKK23064.1 - 2.9e-07 30.2 1.9 0.00036 20.5 0.0 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 KKK23064.1 - 2.8e-05 23.7 0.7 0.00067 19.3 0.1 3.0 2 1 1 3 3 3 1 TPR repeat TPR_9 PF13371.6 KKK23064.1 - 0.00016 21.8 0.1 0.5 10.6 0.0 2.9 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 KKK23064.1 - 0.00035 20.4 0.0 0.009 16.0 0.0 2.7 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 KKK23064.1 - 0.00042 20.9 1.5 0.042 14.5 0.3 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.6 KKK23064.1 - 0.00079 19.9 0.7 23 5.9 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat PB1 PF00564.24 KKK23064.1 - 0.002 18.0 0.0 0.0035 17.2 0.0 1.4 1 0 0 1 1 1 1 PB1 domain Syntaxin-18_N PF10496.9 KKK23065.1 - 0.0026 18.0 3.6 0.016 15.5 0.4 3.5 2 2 1 3 3 3 1 SNARE-complex protein Syntaxin-18 N-terminus SNARE PF05739.19 KKK23065.1 - 0.021 14.8 0.4 0.066 13.2 0.0 2.1 3 0 0 3 3 3 0 SNARE domain Ribosomal_60s PF00428.19 KKK23065.1 - 4 8.1 11.0 0.72 10.5 2.7 2.9 3 0 0 3 3 3 0 60s Acidic ribosomal protein Glyco_hydro_3 PF00933.21 KKK23066.1 - 4e-44 151.3 0.0 5.9e-44 150.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 KKK23066.1 - 3.3e-41 141.5 0.0 1.4e-40 139.5 0.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 KKK23066.1 - 2.5e-21 75.6 1.3 4.5e-21 74.7 1.3 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain DUF572 PF04502.13 KKK23067.1 - 4.8e-29 102.0 0.0 5.4e-29 101.9 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) Cyt-b5 PF00173.28 KKK23068.1 - 3.1e-22 78.5 0.0 5.9e-22 77.6 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Coatomer_E PF04733.14 KKK23075.1 - 3.2e-16 59.6 0.0 3.5e-16 59.5 0.0 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_12 PF13424.6 KKK23075.1 - 1.5e-05 25.2 0.4 0.001 19.3 0.2 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 KKK23075.1 - 0.0012 19.4 0.1 0.26 12.0 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KKK23075.1 - 0.011 16.0 0.0 0.46 10.8 0.0 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 KKK23075.1 - 0.027 14.8 0.1 0.19 12.2 0.0 2.3 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_20 PF14561.6 KKK23075.1 - 0.056 13.8 1.6 0.13 12.6 0.5 2.0 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 KKK23075.1 - 0.089 13.3 2.5 0.31 11.6 1.0 2.3 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_4 PF07721.14 KKK23075.1 - 0.14 12.9 0.1 0.14 12.9 0.1 3.3 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 KKK23075.1 - 0.72 10.8 5.3 9.6 7.3 0.4 3.1 1 1 2 3 3 3 0 Tetratricopeptide repeat Pkinase PF00069.25 KKK23076.1 - 3.7e-46 157.6 0.0 4.7e-46 157.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK23076.1 - 1.5e-26 93.2 0.0 2.2e-26 92.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KKK23077.1 - 5.6e-05 22.6 0.0 0.00011 21.7 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK23077.1 - 0.00053 19.4 0.0 0.0012 18.2 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Dopey_N PF04118.14 KKK23077.1 - 0.012 14.8 0.1 0.019 14.1 0.1 1.3 1 0 0 1 1 1 0 Dopey, N-terminal P4Ha_N PF08336.11 KKK23077.1 - 0.073 13.1 0.2 0.15 12.0 0.2 1.5 1 0 0 1 1 1 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region PNP_UDP_1 PF01048.20 KKK23078.1 - 3.7e-13 49.3 0.0 6.3e-13 48.5 0.0 1.3 1 0 0 1 1 1 1 Phosphorylase superfamily ABC_tran PF00005.27 KKK23079.1 - 3.8e-46 157.0 0.0 8.4e-28 97.6 0.0 2.9 2 1 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KKK23079.1 - 2e-38 132.6 8.9 1.8e-23 83.6 2.3 2.9 2 1 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 KKK23079.1 - 1.1e-09 38.1 0.5 0.12 11.8 0.1 4.2 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 KKK23079.1 - 2.8e-05 24.1 0.0 0.062 13.2 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase DUF87 PF01935.17 KKK23079.1 - 0.00015 21.9 2.6 0.22 11.6 0.0 3.2 3 0 0 3 3 3 2 Helicase HerA, central domain AAA_23 PF13476.6 KKK23079.1 - 0.00018 22.1 0.1 0.029 14.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 KKK23079.1 - 0.00067 19.7 0.0 0.12 12.4 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_29 PF13555.6 KKK23079.1 - 0.001 18.8 0.2 1 9.2 0.1 2.9 3 0 0 3 3 2 1 P-loop containing region of AAA domain AAA_22 PF13401.6 KKK23079.1 - 0.0019 18.5 0.0 5.6 7.2 0.0 3.4 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 KKK23079.1 - 0.0024 18.3 1.4 0.15 12.4 0.1 3.0 3 0 0 3 3 2 1 AAA ATPase domain T2SSE PF00437.20 KKK23079.1 - 0.0038 16.3 0.0 0.71 8.9 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein DUF2275 PF10039.9 KKK23079.1 - 0.023 14.8 0.1 0.054 13.6 0.1 1.6 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2275) DUF2075 PF09848.9 KKK23079.1 - 0.029 13.6 0.0 0.42 9.8 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Zeta_toxin PF06414.12 KKK23079.1 - 0.036 13.3 0.1 2.4 7.4 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin AAA_7 PF12775.7 KKK23079.1 - 0.072 12.6 0.1 7.7 6.0 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region IstB_IS21 PF01695.17 KKK23079.1 - 0.086 12.6 0.2 3.7 7.3 0.0 3.0 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_30 PF13604.6 KKK23079.1 - 0.096 12.4 0.2 19 4.9 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA_25 PF13481.6 KKK23079.1 - 0.11 12.1 0.1 6.9 6.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain MeaB PF03308.16 KKK23079.1 - 0.12 11.3 0.0 0.27 10.2 0.0 1.5 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB CbiA PF01656.23 KKK23079.1 - 0.18 11.9 0.8 12 6.0 0.0 2.6 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_10 PF12846.7 KKK23079.1 - 0.18 10.7 0.3 1.5 7.6 0.0 2.3 2 0 0 2 2 2 0 AAA-like domain TrwB_AAD_bind PF10412.9 KKK23079.1 - 0.2 10.5 1.1 0.81 8.5 0.1 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Mt_ATP-synt_D PF05873.12 KKK23079.1 - 0.21 11.4 0.7 0.46 10.3 0.0 1.8 2 0 0 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) PhoH PF02562.16 KKK23079.1 - 0.21 11.0 0.1 22 4.4 0.0 2.5 2 0 0 2 2 2 0 PhoH-like protein AAA_21 PF13304.6 KKK23079.1 - 1.5 8.5 6.0 29 4.3 0.1 3.7 3 1 0 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system UPF0261 PF06792.11 KKK23080.1 - 1.5e-157 524.7 0.7 2e-157 524.3 0.7 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0261) PEP_hydrolase PF09370.10 KKK23080.1 - 1.7e-132 440.6 0.6 3.1e-132 439.7 0.6 1.5 1 0 0 1 1 1 1 Phosphoenolpyruvate hydrolase-like ABC2_membrane PF01061.24 KKK23081.1 - 4.8e-78 261.4 61.9 2e-40 138.5 25.0 3.2 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 KKK23081.1 - 7.6e-36 123.7 0.0 1.3e-16 61.3 0.0 3.2 3 0 0 3 3 3 2 ABC transporter PDR_CDR PF06422.12 KKK23081.1 - 2.2e-26 91.6 12.6 9.8e-25 86.3 0.1 3.1 3 0 0 3 3 2 2 CDR ABC transporter ABC_trans_N PF14510.6 KKK23081.1 - 6.2e-14 52.4 0.1 2.2e-13 50.6 0.1 2.0 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_16 PF13191.6 KKK23081.1 - 5.3e-05 23.7 0.3 0.017 15.5 0.1 2.6 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 KKK23081.1 - 0.00015 21.7 0.3 0.00095 19.1 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase AAA_25 PF13481.6 KKK23081.1 - 0.00017 21.2 0.1 0.0044 16.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain ABC2_membrane_3 PF12698.7 KKK23081.1 - 0.00032 19.9 23.2 0.00032 19.9 23.2 3.1 2 2 1 3 3 3 2 ABC-2 family transporter protein Zeta_toxin PF06414.12 KKK23081.1 - 0.00048 19.5 0.0 0.0012 18.2 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin AAA_33 PF13671.6 KKK23081.1 - 0.00056 20.1 0.0 0.23 11.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KKK23081.1 - 0.00082 19.1 2.2 0.025 14.3 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_23 PF13476.6 KKK23081.1 - 0.033 14.7 0.0 0.49 10.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KKK23081.1 - 0.046 14.3 0.0 0.4 11.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.6 KKK23081.1 - 0.051 13.4 1.0 0.94 9.2 0.0 2.7 2 1 1 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system cobW PF02492.19 KKK23081.1 - 0.093 12.3 2.4 0.1 12.2 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 KKK23081.1 - 0.11 12.2 0.2 1.6 8.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 KKK23081.1 - 0.15 12.5 0.2 3.1 8.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KKK23081.1 - 0.18 11.7 2.7 4.6 7.1 0.3 2.6 2 0 0 2 2 2 0 NACHT domain MMR_HSR1 PF01926.23 KKK23081.1 - 0.18 11.9 0.0 18 5.4 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase SMC_N PF02463.19 KKK23081.1 - 0.2 11.1 0.2 5.5 6.4 0.0 2.7 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KKK23081.1 - 0.53 10.6 3.0 2.2 8.6 0.0 3.0 3 0 0 3 3 3 0 AAA domain Zn_clus PF00172.18 KKK23082.1 - 2.6e-06 27.4 8.2 5.1e-06 26.5 8.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ala_racemase_N PF01168.20 KKK23084.1 - 7.3e-28 97.7 0.1 8.9e-28 97.4 0.1 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain D-ser_dehydrat PF14031.6 KKK23084.1 - 9.5e-21 74.3 0.0 1.7e-20 73.4 0.0 1.5 1 0 0 1 1 1 1 Putative serine dehydratase domain SDH_alpha PF03313.15 KKK23084.1 - 0.018 14.7 0.7 0.13 11.9 0.5 2.1 2 0 0 2 2 2 0 Serine dehydratase alpha chain Peptidase_S28 PF05577.12 KKK23085.1 - 5.7e-47 160.5 6.5 1.3e-45 156.0 6.4 2.3 1 1 0 1 1 1 1 Serine carboxypeptidase S28 AAA_12 PF13087.6 KKK23086.1 - 2.3e-32 112.3 0.0 1.2e-30 106.7 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KKK23086.1 - 1.3e-28 100.6 0.9 5.3e-28 98.5 0.3 2.3 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KKK23086.1 - 1.5e-10 41.6 0.1 1.6e-09 38.3 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KKK23086.1 - 5.5e-07 29.5 0.0 0.0011 18.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain DUF2075 PF09848.9 KKK23086.1 - 0.0012 18.2 0.2 0.028 13.7 0.0 2.5 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) ResIII PF04851.15 KKK23086.1 - 0.044 13.8 0.0 0.097 12.7 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit GvpK PF05121.12 KKK23086.1 - 1.1 9.4 4.0 0.96 9.5 1.5 2.3 2 0 0 2 2 2 0 Gas vesicle protein K Ldh_1_N PF00056.23 KKK23087.1 - 1.1e-24 87.1 0.4 3.7e-22 78.9 0.4 2.2 1 1 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 KKK23087.1 - 6.3e-15 55.5 0.0 9.4e-15 54.9 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain F420_oxidored PF03807.17 KKK23087.1 - 0.0063 17.1 0.2 0.023 15.3 0.2 2.0 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Glyco_hydro_4 PF02056.16 KKK23087.1 - 0.018 14.6 0.1 0.033 13.8 0.1 1.5 1 1 0 1 1 1 0 Family 4 glycosyl hydrolase ApbA PF02558.16 KKK23087.1 - 0.083 12.5 0.2 0.39 10.4 0.3 2.0 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Methyltransf_25 PF13649.6 KKK23088.1 - 1.9e-15 57.3 0.0 3.3e-14 53.3 0.0 2.8 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_12 PF08242.12 KKK23088.1 - 2.3e-14 53.9 0.0 7.4e-14 52.3 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KKK23088.1 - 6.9e-13 48.8 0.0 1.2e-12 48.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KKK23088.1 - 1.5e-12 48.0 0.0 1.3e-11 45.0 0.0 2.5 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 KKK23088.1 - 7e-10 38.9 0.0 1.1e-09 38.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KKK23088.1 - 6.2e-08 32.3 0.0 3.1e-07 30.0 0.0 1.9 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family DUF3419 PF11899.8 KKK23088.1 - 0.00083 18.6 0.0 0.0016 17.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_24 PF13578.6 KKK23088.1 - 0.0011 19.9 0.0 0.039 15.0 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_8 PF05148.15 KKK23088.1 - 0.0031 17.4 0.0 0.37 10.6 0.0 2.4 2 1 0 2 2 2 1 Hypothetical methyltransferase MTS PF05175.14 KKK23088.1 - 0.0061 16.1 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain NNMT_PNMT_TEMT PF01234.17 KKK23088.1 - 0.0071 15.6 0.0 0.17 11.0 0.0 2.4 1 1 1 3 3 3 1 NNMT/PNMT/TEMT family CMAS PF02353.20 KKK23088.1 - 0.045 13.0 0.0 0.12 11.7 0.0 1.7 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase NMO PF03060.15 KKK23089.1 - 5.4e-29 101.6 2.0 9.9e-23 81.0 0.4 2.2 2 0 0 2 2 2 2 Nitronate monooxygenase IMPDH PF00478.25 KKK23089.1 - 6.1e-11 41.9 0.1 4.3e-06 26.0 1.9 2.1 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 KKK23089.1 - 2.6e-06 26.7 1.2 4.3e-06 26.0 1.2 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 KKK23089.1 - 0.0045 16.2 0.3 0.0067 15.6 0.3 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase DHO_dh PF01180.21 KKK23089.1 - 0.022 14.0 0.1 0.033 13.4 0.1 1.2 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase His_biosynth PF00977.21 KKK23089.1 - 0.11 11.9 0.0 0.45 9.9 0.0 1.9 2 0 0 2 2 2 0 Histidine biosynthesis protein Stk19 PF10494.9 KKK23090.1 - 1.2e-88 297.0 0.0 1.4e-88 296.7 0.0 1.1 1 0 0 1 1 1 1 Serine-threonine protein kinase 19 NmrA PF05368.13 KKK23092.1 - 3.5e-39 134.7 0.0 4.1e-39 134.5 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KKK23092.1 - 2.5e-12 47.1 0.0 3.4e-12 46.6 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KKK23092.1 - 5.5e-05 22.7 0.0 7.7e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.18 KKK23092.1 - 0.0084 16.4 0.1 0.051 13.8 0.1 2.0 2 0 0 2 2 2 1 TrkA-N domain 3Beta_HSD PF01073.19 KKK23092.1 - 0.011 14.8 0.0 0.015 14.3 0.0 1.1 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.20 KKK23092.1 - 0.026 14.6 0.1 0.048 13.8 0.1 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus HPP PF04982.13 KKK23094.1 - 4e-36 123.9 12.2 7.4e-36 123.0 12.2 1.4 1 0 0 1 1 1 1 HPP family Ycf66_N PF07444.11 KKK23094.1 - 0.17 12.0 3.0 1.6 8.9 0.2 2.6 2 0 0 2 2 2 0 Ycf66 protein N-terminus ArAE_1 PF06081.11 KKK23094.1 - 1.8 8.7 8.4 5.3 7.2 8.4 1.7 1 1 0 1 1 1 0 Aromatic acid exporter family member 1 Methyltransf_24 PF13578.6 KKK23095.1 - 1.4e-12 48.6 0.0 2e-12 48.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.17 KKK23095.1 - 6.3e-12 45.1 0.0 8.4e-12 44.7 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase GFO_IDH_MocA PF01408.22 KKK23096.1 - 5.4e-24 85.3 0.0 8.7e-24 84.6 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KKK23096.1 - 8.4e-15 54.8 0.0 1.4e-14 54.1 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.16 KKK23096.1 - 0.00011 22.8 0.0 0.00019 22.1 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain DapB_N PF01113.20 KKK23096.1 - 0.00087 19.4 0.0 0.0016 18.5 0.0 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus ADH_zinc_N_2 PF13602.6 KKK23096.1 - 0.013 16.5 0.1 0.087 13.9 0.0 2.3 3 1 0 3 3 3 0 Zinc-binding dehydrogenase Sacchrp_dh_NADP PF03435.18 KKK23096.1 - 0.014 15.6 0.0 0.025 14.8 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Endonuclease_NS PF01223.23 KKK23097.1 - 8.9e-64 215.4 0.0 1.1e-63 215.1 0.0 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease Ifi-6-16 PF06140.13 KKK23098.1 - 3.3e-07 30.1 26.7 3.3e-07 30.1 26.7 2.2 2 1 0 2 2 2 1 Interferon-induced 6-16 family Fungal_trans_2 PF11951.8 KKK23099.1 - 0.0057 15.5 0.0 0.0095 14.8 0.0 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Phage_holin_7_1 PF16081.5 KKK23099.1 - 0.042 14.0 0.1 0.084 13.1 0.1 1.5 1 0 0 1 1 1 0 Mycobacterial 2 TMS Phage Holin (M2 Hol) Family Sugar_tr PF00083.24 KKK23100.1 - 3.7e-79 266.7 24.6 4.5e-79 266.4 24.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKK23100.1 - 2.5e-18 66.1 49.0 1e-16 60.8 26.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily ABC_tran PF00005.27 KKK23101.1 - 1.6e-47 161.5 0.1 3.1e-22 79.6 0.0 2.7 3 0 0 3 3 2 2 ABC transporter ABC_tran_Xtn PF12848.7 KKK23101.1 - 2.5e-21 75.5 2.0 2.5e-21 75.5 2.0 2.9 3 0 0 3 3 2 1 ABC transporter AAA_21 PF13304.6 KKK23101.1 - 5.1e-17 62.6 0.5 0.0012 18.7 0.0 4.2 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KKK23101.1 - 4.9e-11 42.5 0.4 0.0096 15.4 0.1 4.4 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KKK23101.1 - 9e-08 31.8 0.3 0.002 17.8 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 KKK23101.1 - 6.4e-07 30.1 5.1 0.053 14.0 0.0 3.6 3 1 0 3 3 3 2 AAA domain AAA_15 PF13175.6 KKK23101.1 - 2.3e-06 27.6 0.0 0.038 13.7 0.0 2.9 3 0 0 3 3 3 2 AAA ATPase domain RsgA_GTPase PF03193.16 KKK23101.1 - 3.8e-06 26.9 0.9 0.0054 16.6 0.0 2.8 3 0 0 3 3 3 2 RsgA GTPase MMR_HSR1 PF01926.23 KKK23101.1 - 1.4e-05 25.1 0.0 0.027 14.6 0.0 3.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KKK23101.1 - 1.9e-05 25.1 0.0 0.13 12.7 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 KKK23101.1 - 3.2e-05 24.2 0.0 0.17 12.1 0.0 2.7 2 1 0 2 2 2 2 AAA domain NB-ARC PF00931.22 KKK23101.1 - 3.7e-05 23.0 0.0 0.41 9.8 0.0 3.2 2 1 0 2 2 2 2 NB-ARC domain NACHT PF05729.12 KKK23101.1 - 0.00012 22.0 0.2 0.17 11.8 0.0 2.6 2 0 0 2 2 2 2 NACHT domain AAA_18 PF13238.6 KKK23101.1 - 0.00013 22.6 0.1 0.067 13.7 0.0 3.0 3 0 0 3 3 2 1 AAA domain RNA_helicase PF00910.22 KKK23101.1 - 0.0002 21.7 0.5 1.9 8.9 0.0 3.3 3 0 0 3 3 3 2 RNA helicase AAA PF00004.29 KKK23101.1 - 0.00026 21.4 0.1 1.1 9.7 0.0 3.2 3 1 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 KKK23101.1 - 0.00026 21.3 0.0 0.094 13.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_27 PF13514.6 KKK23101.1 - 0.00035 20.2 0.5 0.2 11.2 0.0 2.7 3 0 0 3 3 2 1 AAA domain AAA_33 PF13671.6 KKK23101.1 - 0.00047 20.3 1.8 0.2 11.8 0.1 3.1 4 0 0 4 4 2 1 AAA domain Roc PF08477.13 KKK23101.1 - 0.0012 19.0 0.0 2.2 8.5 0.0 3.0 2 1 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_5 PF07728.14 KKK23101.1 - 0.0013 18.7 0.2 1.8 8.5 0.1 2.6 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 KKK23101.1 - 0.0014 18.4 0.7 1.9 8.2 0.1 3.4 4 0 0 4 4 3 1 AAA domain AAA_14 PF13173.6 KKK23101.1 - 0.0016 18.4 0.0 1.9 8.5 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 KKK23101.1 - 0.0062 16.1 0.1 2 7.9 0.0 2.8 3 0 0 3 3 3 1 P-loop containing dynein motor region GST_C_3 PF14497.6 KKK23101.1 - 0.014 15.6 0.2 0.036 14.2 0.2 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DUF87 PF01935.17 KKK23101.1 - 0.026 14.6 0.5 8.6 6.4 0.0 3.1 3 0 0 3 3 3 0 Helicase HerA, central domain ATPase_2 PF01637.18 KKK23101.1 - 0.026 14.4 0.1 3.2 7.6 0.0 2.6 3 0 0 3 3 2 0 ATPase domain predominantly from Archaea Phage_tail_2 PF06199.11 KKK23101.1 - 0.03 14.4 0.0 0.077 13.1 0.0 1.7 1 1 0 1 1 1 0 Phage tail tube protein AAA_25 PF13481.6 KKK23101.1 - 0.035 13.7 0.0 1.2 8.7 0.0 2.8 3 0 0 3 3 3 0 AAA domain Dynamin_N PF00350.23 KKK23101.1 - 0.035 14.1 4.4 7.6 6.6 0.0 4.0 4 1 0 4 4 4 0 Dynamin family NTPase_1 PF03266.15 KKK23101.1 - 0.04 13.8 0.1 3.9 7.4 0.1 2.6 2 0 0 2 2 2 0 NTPase DUF2813 PF11398.8 KKK23101.1 - 0.048 12.9 1.3 5.9 6.0 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2813) Ras PF00071.22 KKK23101.1 - 0.052 13.1 0.0 4.7 6.8 0.0 2.6 2 0 0 2 2 2 0 Ras family FeoB_N PF02421.18 KKK23101.1 - 0.077 12.5 0.1 4.8 6.7 0.0 2.9 3 0 0 3 3 3 0 Ferrous iron transport protein B MCM PF00493.23 KKK23101.1 - 0.09 11.9 0.1 2.9 6.9 0.0 2.2 2 0 0 2 2 2 0 MCM P-loop domain DAP3 PF10236.9 KKK23101.1 - 0.11 11.7 0.4 9.2 5.3 0.0 2.8 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 zf-RING_UBOX PF13445.6 KKK23102.1 - 2.7e-06 27.3 11.4 6.6e-06 26.0 2.9 3.0 2 1 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 KKK23102.1 - 2.5e-05 24.5 12.9 0.00013 22.3 2.8 2.9 3 0 0 3 3 3 2 Ring finger domain zf-C3HC4_2 PF13923.6 KKK23102.1 - 0.00015 21.6 11.5 0.00022 21.0 3.5 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KKK23102.1 - 0.00038 20.3 6.9 0.00038 20.3 6.9 2.8 2 2 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KKK23102.1 - 0.001 18.9 2.1 0.001 18.9 2.1 3.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KKK23102.1 - 0.0012 18.7 3.5 0.0012 18.7 3.5 3.1 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-NOSIP PF15906.5 KKK23102.1 - 0.0017 18.4 0.0 0.0041 17.2 0.0 1.7 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein zf-C3HC4_5 PF17121.5 KKK23102.1 - 0.0026 17.6 2.6 0.0079 16.1 2.6 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FYVE PF01363.21 KKK23102.1 - 0.0052 16.9 11.4 0.0097 16.0 4.0 3.1 2 2 0 2 2 2 1 FYVE zinc finger Rtf2 PF04641.12 KKK23102.1 - 2.1 7.6 33.5 0.25 10.7 8.9 3.9 2 2 1 3 3 3 0 Rtf2 RING-finger Atg14 PF10186.9 KKK23102.1 - 2.7 7.0 17.2 0.039 13.1 9.5 1.8 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DFRP_C PF16543.5 KKK23103.1 - 4.1e-25 88.1 10.0 4.1e-25 88.1 10.0 4.2 3 2 1 4 4 4 1 DRG Family Regulatory Proteins, Tma46 zf-CCCH_4 PF18044.1 KKK23103.1 - 1.6e-05 24.5 7.8 0.0002 21.1 1.6 3.3 3 0 0 3 3 3 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 KKK23103.1 - 2.9e-05 23.9 6.1 2.9e-05 23.9 6.1 3.1 3 0 0 3 3 3 1 Zinc finger domain Torus PF16131.5 KKK23103.1 - 4.3e-05 24.2 5.4 4.3e-05 24.2 5.4 3.8 2 2 1 3 3 3 2 Torus domain zf-CCCH PF00642.24 KKK23103.1 - 5e-05 23.1 0.9 5e-05 23.1 0.9 2.6 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_3 PF15663.5 KKK23103.1 - 0.0034 17.6 0.4 0.29 11.3 0.1 2.7 2 0 0 2 2 2 1 Zinc-finger containing family zf-CCCH_2 PF14608.6 KKK23103.1 - 0.013 16.0 13.4 0.032 14.7 3.7 2.9 2 1 0 2 2 2 0 RNA-binding, Nab2-type zinc finger Glucosamine_iso PF01182.20 KKK23117.1 - 9.1e-68 228.5 0.0 1e-67 228.3 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Na_H_Exchanger PF00999.21 KKK23118.1 - 3.2e-60 203.9 45.6 4.5e-60 203.4 45.6 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Usp PF00582.26 KKK23118.1 - 0.0042 17.6 0.0 0.093 13.2 0.0 2.5 2 0 0 2 2 2 1 Universal stress protein family GFA PF04828.14 KKK23119.1 - 7.3e-07 29.5 2.2 1.2e-06 28.7 2.2 1.4 1 1 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme PHD_Oberon PF07227.11 KKK23119.1 - 0.032 14.1 3.3 0.15 12.0 0.3 2.2 2 0 0 2 2 2 0 PHD - plant homeodomain finger protein Mod_r PF07200.13 KKK23120.1 - 8e-24 84.4 5.9 9.6e-24 84.2 5.9 1.1 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein Fib_alpha PF08702.10 KKK23120.1 - 0.032 14.4 0.4 0.069 13.3 0.4 1.5 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family GIT_CC PF16559.5 KKK23120.1 - 0.085 12.7 0.9 0.17 11.8 0.9 1.4 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor PSK_trans_fac PF07704.11 KKK23120.1 - 0.14 12.9 5.4 0.098 13.4 3.3 1.7 2 0 0 2 2 2 0 Rv0623-like transcription factor Ank_5 PF13857.6 KKK23121.1 - 4.5e-10 39.6 0.1 5.8e-07 29.7 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 KKK23121.1 - 4.9e-09 36.5 0.1 3.4e-05 24.3 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KKK23121.1 - 9.9e-08 32.5 0.1 1.7e-07 31.7 0.1 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KKK23121.1 - 1e-06 28.6 0.6 0.00013 22.1 0.1 3.2 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.30 KKK23121.1 - 0.013 15.9 0.4 0.072 13.6 0.1 2.4 3 0 0 3 3 3 0 Ankyrin repeat YejG PF13989.6 KKK23121.1 - 0.017 15.5 0.0 0.03 14.8 0.0 1.4 1 0 0 1 1 1 0 YejG-like protein Got1 PF04178.12 KKK23122.1 - 9.3e-33 113.0 18.3 1.8e-32 112.1 18.3 1.4 1 1 0 1 1 1 1 Got1/Sft2-like family tRNA_lig_CPD PF08302.11 KKK23123.1 - 1.7e-87 293.1 0.0 2.5e-87 292.5 0.0 1.2 1 0 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain RNA_lig_T4_1 PF09511.10 KKK23123.1 - 2.3e-72 243.4 0.0 5.8e-72 242.1 0.0 1.7 1 0 0 1 1 1 1 RNA ligase tRNA_lig_kinase PF08303.11 KKK23123.1 - 2.2e-52 177.6 0.0 3.8e-52 176.8 0.0 1.4 1 0 0 1 1 1 1 tRNA ligase kinase domain AAA_18 PF13238.6 KKK23123.1 - 0.075 13.6 0.3 1.5 9.4 0.1 3.0 2 1 0 2 2 2 0 AAA domain Mito_carr PF00153.27 KKK23124.1 - 5.6e-40 135.2 0.5 1.8e-19 69.4 0.0 2.3 2 0 0 2 2 2 2 Mitochondrial carrier protein HLH PF00010.26 KKK23125.1 - 3.3e-12 46.2 0.0 1.3e-11 44.2 0.0 2.0 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF4554 PF15091.6 KKK23125.1 - 0.22 10.4 0.6 0.32 9.8 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) La PF05383.17 KKK23127.1 - 2.3e-20 72.4 0.5 4.1e-20 71.6 0.5 1.4 1 0 0 1 1 1 1 La domain TYW3 PF02676.14 KKK23128.1 - 1.4e-74 250.1 0.0 1.7e-74 249.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase TYW3 DUF2461 PF09365.10 KKK23130.1 - 1.7e-78 263.3 0.0 2.4e-78 262.9 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein (DUF2461) Red1 PF07964.11 KKK23130.1 - 0.55 8.4 15.8 0.78 7.9 15.8 1.1 1 0 0 1 1 1 0 Rec10 / Red1 Presenilin PF01080.17 KKK23130.1 - 1.4 7.7 7.3 2 7.1 7.3 1.1 1 0 0 1 1 1 0 Presenilin Macoilin PF09726.9 KKK23130.1 - 4.6 5.7 7.7 6.2 5.3 7.7 1.2 1 0 0 1 1 1 0 Macoilin family 4HBT PF03061.22 KKK23131.1 - 0.0012 19.1 0.0 0.002 18.4 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily TRI12 PF06609.13 KKK23132.1 - 1.4e-37 129.5 25.0 1.7e-37 129.2 25.0 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 KKK23132.1 - 4.9e-16 58.6 56.2 4.9e-16 58.6 56.2 3.0 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KKK23132.1 - 1.1e-09 37.7 35.1 5.1e-09 35.5 10.5 2.8 2 1 1 3 3 3 2 Sugar (and other) transporter Cation_ATPase_C PF00689.21 KKK23132.1 - 0.0004 20.1 5.0 0.0004 20.1 5.0 2.5 2 1 0 2 2 2 1 Cation transporting ATPase, C-terminus ARPC4 PF05856.12 KKK23133.1 - 7.2e-79 263.2 3.9 8.1e-79 263.0 3.9 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) UCH PF00443.29 KKK23134.1 - 1.7e-51 175.2 0.1 2.1e-51 174.9 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KKK23134.1 - 8.8e-12 45.2 8.1 9e-11 41.9 8.1 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 KKK23134.1 - 7e-11 41.7 0.1 2.1e-10 40.2 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin family Pec_lyase_C PF00544.19 KKK23136.1 - 1.5e-07 31.2 5.3 7.4e-07 29.0 5.3 2.1 1 1 0 1 1 1 1 Pectate lyase Strep_his_triad PF04270.13 KKK23141.1 - 3.2 7.8 4.4 36 4.4 0.4 2.4 2 0 0 2 2 2 0 Streptococcal histidine triad protein FAD_binding_4 PF01565.23 KKK23142.1 - 2.8e-13 49.8 0.0 4.6e-13 49.1 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Glyco_hydro_25 PF01183.20 KKK23143.1 - 1.9e-23 83.6 0.1 1.3e-22 80.9 0.0 1.8 1 1 1 2 2 2 1 Glycosyl hydrolases family 25 Methyltransf_23 PF13489.6 KKK23144.1 - 3.3e-20 72.6 0.0 4.8e-20 72.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKK23144.1 - 8.1e-12 45.7 0.0 2.5e-11 44.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KKK23144.1 - 7.3e-11 42.7 0.0 6.1e-10 39.7 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KKK23144.1 - 1.2e-10 41.9 0.0 2.5e-10 40.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KKK23144.1 - 6.8e-10 38.9 0.0 1.9e-08 34.2 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KKK23144.1 - 0.00069 19.2 0.0 0.0012 18.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 KKK23144.1 - 0.0027 17.1 0.0 0.043 13.1 0.0 2.5 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family PrmA PF06325.13 KKK23144.1 - 0.011 15.1 0.0 0.018 14.5 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.9 KKK23144.1 - 0.018 14.8 0.0 0.028 14.2 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_4 PF02390.17 KKK23144.1 - 0.026 14.0 0.0 0.047 13.2 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase FtsJ PF01728.19 KKK23144.1 - 0.042 14.0 0.0 0.11 12.6 0.0 1.6 1 1 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_2 PF00891.18 KKK23144.1 - 0.046 13.0 0.0 0.083 12.2 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain PLA2_B PF01735.18 KKK23145.1 - 1.5e-182 607.4 1.3 1.8e-182 607.2 1.3 1.0 1 0 0 1 1 1 1 Lysophospholipase catalytic domain DUF3425 PF11905.8 KKK23146.1 - 4.5e-15 55.7 0.0 7.6e-15 55.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 KKK23146.1 - 0.028 14.5 9.3 0.049 13.7 9.3 1.3 1 0 0 1 1 1 0 bZIP transcription factor He_PIG_assoc PF10632.9 KKK23146.1 - 0.2 11.3 0.8 0.39 10.4 0.0 1.9 2 0 0 2 2 2 0 He_PIG associated, NEW1 domain of bacterial glycohydrolase Methyltransf_2 PF00891.18 KKK23147.1 - 2.9e-25 88.8 0.0 1.8e-24 86.2 0.0 2.0 1 1 0 1 1 1 1 O-methyltransferase domain Dimerisation2 PF16864.5 KKK23147.1 - 0.0063 16.5 0.0 0.021 14.8 0.0 1.9 1 0 0 1 1 1 1 Dimerisation domain Dimerisation PF08100.11 KKK23147.1 - 0.028 14.4 0.1 0.13 12.4 0.1 2.1 1 1 0 1 1 1 0 Dimerisation domain Methyltransf_33 PF10017.9 KKK23147.1 - 0.038 13.1 0.0 0.77 8.8 0.0 2.1 2 0 0 2 2 2 0 Histidine-specific methyltransferase, SAM-dependent DUF2550 PF10739.9 KKK23148.1 - 0.015 15.3 0.0 0.03 14.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2550) SNAD3 PF18749.1 KKK23148.1 - 0.095 11.8 0.0 0.12 11.5 0.0 1.1 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 3 PIG-L PF02585.17 KKK23149.1 - 5.2e-19 69.2 0.2 1.2e-18 68.0 0.2 1.6 1 1 0 1 1 1 1 GlcNAc-PI de-N-acetylase FA_hydroxylase PF04116.13 KKK23150.1 - 1.9e-27 96.2 11.1 1.9e-27 96.2 11.1 2.1 3 0 0 3 3 3 1 Fatty acid hydroxylase superfamily NmrA PF05368.13 KKK23152.1 - 1.3e-37 129.6 0.0 1.6e-37 129.3 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KKK23152.1 - 6.3e-13 49.0 0.1 9.4e-13 48.5 0.1 1.2 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KKK23152.1 - 2.5e-05 23.4 0.0 3.5e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KKK23152.1 - 3.7e-05 23.3 0.0 5.5e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.18 KKK23152.1 - 0.001 19.3 0.0 0.0016 18.7 0.0 1.3 1 0 0 1 1 1 1 TrkA-N domain Sacchrp_dh_NADP PF03435.18 KKK23152.1 - 0.0096 16.2 0.0 0.027 14.7 0.0 1.7 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 KKK23152.1 - 0.095 13.1 0.0 0.17 12.3 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 KKK23152.1 - 0.2 11.8 0.0 0.35 11.0 0.0 1.3 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus FGGY_N PF00370.21 KKK23161.1 - 3.8e-69 233.0 0.0 5e-69 232.6 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 KKK23161.1 - 7.2e-60 202.1 2.5 3e-57 193.5 2.5 2.5 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain MIP PF00230.20 KKK23162.1 - 1.4e-54 185.2 5.0 1.7e-54 184.9 5.0 1.1 1 0 0 1 1 1 1 Major intrinsic protein ABC2_membrane PF01061.24 KKK23163.1 - 8.5e-71 237.7 48.4 1.8e-43 148.4 16.3 3.9 4 0 0 4 4 4 3 ABC-2 type transporter ABC_tran PF00005.27 KKK23163.1 - 8.6e-39 133.2 0.0 1.9e-18 67.3 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 KKK23163.1 - 2.3e-26 91.5 5.2 1.8e-25 88.7 0.0 3.5 3 0 0 3 3 3 1 CDR ABC transporter AAA_16 PF13191.6 KKK23163.1 - 1.1e-05 25.8 0.1 0.012 16.0 0.1 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.6 KKK23163.1 - 1.2e-05 25.0 0.3 0.0046 16.6 0.1 3.0 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.6 KKK23163.1 - 9e-05 23.0 0.0 0.21 12.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 KKK23163.1 - 0.00013 22.2 0.3 0.91 9.8 0.2 2.8 2 1 0 2 2 2 2 AAA domain ABC_trans_N PF14510.6 KKK23163.1 - 0.00052 20.6 0.0 0.0013 19.3 0.0 1.7 1 0 0 1 1 1 1 ABC-transporter N-terminal RsgA_GTPase PF03193.16 KKK23163.1 - 0.0006 19.8 0.1 0.0099 15.8 0.0 2.6 3 0 0 3 3 3 1 RsgA GTPase AAA_29 PF13555.6 KKK23163.1 - 0.0012 18.6 0.9 0.091 12.5 0.1 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_33 PF13671.6 KKK23163.1 - 0.0016 18.6 0.1 1.5 8.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain PduV-EutP PF10662.9 KKK23163.1 - 0.0031 17.3 0.4 2.9 7.6 0.0 2.5 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation cobW PF02492.19 KKK23163.1 - 0.0038 16.8 0.7 1.7 8.2 0.3 2.5 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.6 KKK23163.1 - 0.011 15.9 1.8 1.4 9.1 1.2 2.5 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KKK23163.1 - 0.018 15.0 0.3 3.2 7.7 0.1 2.4 2 0 0 2 2 2 0 NACHT domain AAA_17 PF13207.6 KKK23163.1 - 0.019 15.4 0.5 0.84 10.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KKK23163.1 - 0.12 12.1 0.8 7 6.3 0.5 2.4 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.6 KKK23163.1 - 0.17 11.7 0.3 5.7 6.6 0.0 2.6 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system Zeta_toxin PF06414.12 KKK23163.1 - 0.27 10.5 0.4 5.8 6.1 0.2 2.2 2 0 0 2 2 2 0 Zeta toxin Peptidase_M28 PF04389.17 KKK23164.1 - 3.4e-40 137.9 0.0 6.5e-40 136.9 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 KKK23164.1 - 1.1e-11 44.6 0.1 2.2e-11 43.6 0.1 1.5 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 KKK23164.1 - 0.00048 19.9 0.0 0.0011 18.7 0.0 1.7 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.14 KKK23164.1 - 0.067 12.2 0.0 0.25 10.3 0.0 2.0 3 0 0 3 3 3 0 M42 glutamyl aminopeptidase Amino_oxidase PF01593.24 KKK23165.1 - 7e-27 94.8 0.1 1.2e-26 94.1 0.1 1.3 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KKK23165.1 - 2.7e-15 56.3 0.1 1.3e-14 54.2 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KKK23165.1 - 1.2e-11 44.8 0.1 5.6e-07 29.5 0.0 2.5 2 1 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KKK23165.1 - 0.00041 19.6 0.0 0.0042 16.2 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 KKK23165.1 - 0.00086 18.6 0.0 0.0015 17.8 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 KKK23165.1 - 0.0012 18.1 0.0 0.0085 15.4 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KKK23165.1 - 0.004 16.5 0.0 0.01 15.2 0.0 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KKK23165.1 - 0.0064 16.5 0.1 0.061 13.3 0.0 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 KKK23165.1 - 0.01 16.4 0.0 0.91 10.1 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KKK23165.1 - 0.055 12.2 0.0 0.15 10.7 0.0 1.7 2 0 0 2 2 2 0 HI0933-like protein GMC_oxred_N PF00732.19 KKK23165.1 - 0.099 12.0 0.0 0.22 10.9 0.0 1.6 1 0 0 1 1 1 0 GMC oxidoreductase MCRA PF06100.11 KKK23165.1 - 0.22 10.3 0.0 0.34 9.6 0.0 1.3 1 0 0 1 1 1 0 MCRA family zf-CCCH_2 PF14608.6 KKK23166.1 - 6e-12 45.6 60.4 0.00012 22.4 14.0 5.5 5 0 0 5 5 5 5 RNA-binding, Nab2-type zinc finger Mago-bind PF09282.10 KKK23167.1 - 8.6e-14 51.1 6.4 1.6e-13 50.3 6.4 1.5 1 0 0 1 1 1 1 Mago binding UCR_UQCRX_QCR9 PF05365.12 KKK23168.1 - 9.7e-26 89.5 1.4 1.6e-25 88.8 1.4 1.4 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like Glyco_hydro_cc PF11790.8 KKK23169.1 - 3.9e-64 216.5 1.6 4.7e-64 216.2 1.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core zf-UBR PF02207.20 KKK23170.1 - 8.6e-19 67.5 15.3 2.4e-18 66.1 15.3 1.8 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.17 KKK23170.1 - 0.0048 16.7 0.0 0.012 15.3 0.0 1.7 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS zf-RING_5 PF14634.6 KKK23170.1 - 0.0057 16.6 0.7 0.0057 16.6 0.7 4.0 3 1 1 4 4 4 1 zinc-RING finger domain zf-RING_2 PF13639.6 KKK23170.1 - 0.0095 16.3 0.6 0.0095 16.3 0.6 4.4 4 1 1 5 5 5 1 Ring finger domain BUD22 PF09073.10 KKK23170.1 - 7.7 5.7 12.0 14 4.9 12.0 1.3 1 0 0 1 1 1 0 BUD22 RED_N PF07808.13 KKK23171.1 - 1.6e-06 27.9 1.9 1.6e-06 27.9 1.9 2.4 2 1 0 2 2 2 1 RED-like protein N-terminal region GvpG PF05120.12 KKK23171.1 - 0.031 14.3 1.4 0.085 12.9 0.4 2.1 2 0 0 2 2 2 0 Gas vesicle protein G FNIP_N PF14636.6 KKK23171.1 - 0.069 14.1 11.5 0.099 13.6 8.5 2.6 3 0 0 3 3 3 0 Folliculin-interacting protein N-terminus FMO-like PF00743.19 KKK23200.1 - 8.1e-13 47.6 0.0 2.3e-11 42.9 0.0 2.1 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KKK23200.1 - 4e-12 46.0 0.0 1.5e-10 40.9 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KKK23200.1 - 3.5e-11 42.9 0.0 2.1e-10 40.3 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KKK23200.1 - 2.6e-05 24.3 0.7 0.00013 22.2 0.0 2.4 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KKK23200.1 - 8.5e-05 21.9 0.8 0.0094 15.2 0.0 2.2 2 0 0 2 2 2 2 Thi4 family K_oxygenase PF13434.6 KKK23200.1 - 0.00024 20.4 0.0 0.0031 16.7 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 KKK23200.1 - 0.00024 21.1 0.6 0.0055 16.7 0.0 3.0 3 1 0 3 3 3 1 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.21 KKK23200.1 - 0.0053 16.1 0.1 0.03 13.6 0.0 2.1 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.7 KKK23200.1 - 0.011 15.2 0.0 0.041 13.2 0.0 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox PF00070.27 KKK23200.1 - 0.043 14.4 0.3 9.5 6.9 0.1 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KKK23200.1 - 0.062 12.9 0.3 11 5.5 0.0 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KKK23200.1 - 0.12 11.5 0.0 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Amino_oxidase PF01593.24 KKK23200.1 - 0.12 11.6 0.0 7.8 5.7 0.0 2.8 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase Fungal_trans PF04082.18 KKK23201.1 - 4.9e-28 97.9 3.5 8e-28 97.2 3.5 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 KKK23201.1 - 1.1e-05 25.6 15.3 0.0071 16.7 0.3 3.2 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KKK23201.1 - 0.011 16.5 13.7 0.15 13.0 0.4 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KKK23201.1 - 2.4 8.3 6.1 0.39 10.8 0.1 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger DUF150_C PF17384.2 KKK23202.1 - 0.091 12.9 0.0 3.1 8.0 0.0 2.7 3 0 0 3 3 3 0 RimP C-terminal SH3 domain SnoaL PF07366.12 KKK23204.1 - 0.00017 21.4 0.0 0.00036 20.3 0.0 1.5 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 KKK23204.1 - 0.00031 21.3 0.0 0.0006 20.4 0.0 1.5 1 0 0 1 1 1 1 SnoaL-like domain TFIIA_gamma_C PF02751.14 KKK23205.1 - 8.7e-26 89.8 2.2 1.6e-25 89.0 2.2 1.4 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit TFIIA_gamma_N PF02268.16 KKK23205.1 - 2.8e-24 84.9 0.2 3.8e-24 84.4 0.2 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain ThiF PF00899.21 KKK23207.1 - 6.3e-112 372.8 0.0 8.7e-75 251.2 0.0 2.5 2 1 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 KKK23207.1 - 7.8e-95 317.6 0.1 3.4e-94 315.5 0.1 2.1 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site E1_UFD PF09358.10 KKK23207.1 - 1.8e-30 105.5 0.1 4e-30 104.4 0.1 1.7 1 0 0 1 1 1 1 Ubiquitin fold domain E1_FCCH PF16190.5 KKK23207.1 - 3.7e-29 100.7 0.2 7.7e-29 99.7 0.2 1.6 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain E1_4HB PF16191.5 KKK23207.1 - 6.6e-25 87.1 2.7 1.1e-24 86.4 0.8 2.4 3 0 0 3 3 3 1 Ubiquitin-activating enzyme E1 four-helix bundle GST_N_2 PF13409.6 KKK23207.1 - 1.4e-14 54.2 0.0 3.4e-14 52.9 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Pkinase PF00069.25 KKK23207.1 - 6.5e-14 51.9 0.0 1.2e-13 51.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK23207.1 - 7e-11 41.9 0.0 1.5e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase GST_N_3 PF13417.6 KKK23207.1 - 0.011 16.2 0.1 0.054 13.9 0.1 2.2 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GCP_N_terminal PF17681.1 KKK23208.1 - 1.3e-37 130.1 0.0 2.3e-37 129.3 0.0 1.3 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 KKK23208.1 - 6e-20 71.9 0.0 2.4e-19 70.0 0.0 1.9 1 1 0 1 1 1 1 Gamma tubulin complex component C-terminal Sec66 PF09802.9 KKK23208.1 - 0.064 12.8 0.4 0.12 12.0 0.4 1.3 1 0 0 1 1 1 0 Preprotein translocase subunit Sec66 adh_short_C2 PF13561.6 KKK23209.1 - 7e-54 182.8 2.9 8.5e-54 182.6 2.9 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KKK23209.1 - 1.1e-46 158.8 1.3 1.3e-46 158.5 1.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KKK23209.1 - 2.8e-14 53.4 1.7 4.1e-14 52.9 1.7 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KKK23209.1 - 3.9e-06 26.5 1.2 6.8e-06 25.7 1.2 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KKK23209.1 - 0.021 14.2 0.2 0.029 13.8 0.2 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase MFS_1 PF07690.16 KKK23210.1 - 2.7e-31 108.8 26.0 2.7e-31 108.8 26.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1201 PF06716.11 KKK23210.1 - 0.017 15.1 1.9 0.024 14.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1201) GILT PF03227.16 KKK23212.1 - 4.2e-14 52.7 0.4 9.9e-14 51.5 0.3 1.7 1 1 0 1 1 1 1 Gamma interferon inducible lysosomal thiol reductase (GILT) Hexokinase_1 PF00349.21 KKK23213.1 - 1.9e-59 200.9 0.0 2.8e-59 200.4 0.0 1.3 1 0 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.16 KKK23213.1 - 2.6e-47 161.3 0.0 1.6e-46 158.7 0.0 2.0 1 1 0 1 1 1 1 Hexokinase Abhydrolase_3 PF07859.13 KKK23215.1 - 6.6e-19 68.6 0.0 1.2e-18 67.8 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KKK23215.1 - 2e-11 43.4 0.0 2.5e-11 43.1 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase NAD_binding_8 PF13450.6 KKK23216.1 - 2.9e-11 43.4 0.0 1.3e-08 34.9 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KKK23216.1 - 4.5e-11 42.5 0.0 1.9e-07 30.6 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KKK23216.1 - 1.7e-09 37.4 0.0 1.1e-08 34.7 0.0 2.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KKK23216.1 - 2.9e-09 35.9 0.0 1.5e-08 33.5 0.0 1.9 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like DAO PF01266.24 KKK23216.1 - 9.2e-08 32.0 0.6 4.2e-05 23.3 0.1 3.4 3 1 1 4 4 4 1 FAD dependent oxidoreductase Thi4 PF01946.17 KKK23216.1 - 4.4e-07 29.4 0.0 1.2e-05 24.7 0.0 2.1 2 0 0 2 2 2 1 Thi4 family K_oxygenase PF13434.6 KKK23216.1 - 1e-05 24.9 0.0 0.0013 17.9 0.0 2.5 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 KKK23216.1 - 1.7e-05 25.3 0.0 0.11 13.1 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KKK23216.1 - 0.0032 16.8 0.0 0.0045 16.3 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.12 KKK23216.1 - 0.0061 15.7 0.0 0.44 9.6 0.0 2.5 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 KKK23216.1 - 0.007 15.5 0.0 0.039 13.0 0.0 2.2 3 0 0 3 3 3 1 FAD binding domain NAD_binding_9 PF13454.6 KKK23216.1 - 0.031 14.3 0.1 3.6 7.6 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding NAD_binding_7 PF13241.6 KKK23216.1 - 0.035 14.5 0.0 0.084 13.3 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding Shikimate_DH PF01488.20 KKK23216.1 - 0.079 13.0 0.0 0.79 9.8 0.0 2.1 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase HI0933_like PF03486.14 KKK23216.1 - 0.12 11.1 0.0 0.5 9.0 0.0 1.8 2 0 0 2 2 2 0 HI0933-like protein GIDA PF01134.22 KKK23216.1 - 0.26 10.3 0.1 0.54 9.3 0.1 1.5 1 0 0 1 1 1 0 Glucose inhibited division protein A Cupin_8 PF13621.6 KKK23217.1 - 9.8e-38 130.3 0.0 2.1e-37 129.2 0.0 1.5 1 0 0 1 1 1 1 Cupin-like domain LCM PF04072.14 KKK23217.1 - 2.9e-17 63.2 0.0 4.9e-17 62.5 0.0 1.3 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Kelch_4 PF13418.6 KKK23217.1 - 9.5e-15 54.3 13.5 4.1e-05 23.5 0.0 5.9 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_5 PF13854.6 KKK23217.1 - 6.1e-09 35.7 0.0 7.5e-05 22.6 0.0 3.7 3 0 0 3 3 3 2 Kelch motif Cupin_4 PF08007.12 KKK23217.1 - 0.0002 21.0 0.0 0.00044 19.8 0.0 1.5 1 0 0 1 1 1 1 Cupin superfamily protein Kelch_6 PF13964.6 KKK23217.1 - 0.08 13.3 1.4 2.3 8.7 0.1 3.7 4 0 0 4 4 4 0 Kelch motif Kelch_3 PF13415.6 KKK23217.1 - 0.44 10.9 9.8 3 8.2 0.3 3.5 3 0 0 3 3 3 0 Galactose oxidase, central domain DSPc PF00782.20 KKK23218.1 - 4.6e-30 104.1 0.0 2.4e-22 79.2 0.0 2.2 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KKK23218.1 - 9.3e-05 22.1 0.0 0.0026 17.4 0.0 2.2 2 0 0 2 2 2 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 KKK23218.1 - 0.018 15.1 0.0 0.1 12.7 0.1 2.1 2 0 0 2 2 2 0 Inositol hexakisphosphate Met_10 PF02475.16 KKK23219.1 - 0.00025 20.8 0.0 0.00098 18.9 0.0 2.0 2 1 0 2 2 2 1 Met-10+ like-protein Peptidase_M60 PF13402.6 KKK23219.1 - 0.13 11.8 0.5 0.2 11.2 0.5 1.2 1 0 0 1 1 1 0 Peptidase M60, enhancin and enhancin-like Catalase-rel PF06628.12 KKK23219.1 - 0.17 12.1 0.0 0.48 10.7 0.0 1.7 1 0 0 1 1 1 0 Catalase-related immune-responsive EF-hand_6 PF13405.6 KKK23220.1 - 1e-09 37.5 0.2 0.0018 18.1 0.0 3.1 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 KKK23220.1 - 3.2e-05 24.3 2.4 0.0064 16.9 0.8 2.8 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 KKK23220.1 - 0.00057 19.2 0.1 0.0032 16.9 0.0 2.2 2 0 0 2 2 2 1 EF hand TPR_14 PF13428.6 KKK23221.1 - 0.64 11.0 2.7 27 5.9 0.1 3.4 1 1 1 2 2 2 0 Tetratricopeptide repeat ANAPC4_WD40 PF12894.7 KKK23222.1 - 0.00016 21.9 0.0 0.05 13.9 0.0 3.5 4 1 1 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KKK23222.1 - 0.00064 20.5 0.1 0.27 12.2 0.0 4.0 5 0 0 5 5 5 1 WD domain, G-beta repeat CNH PF00780.22 KKK23222.1 - 0.00071 19.3 0.1 0.2 11.3 0.1 2.4 2 0 0 2 2 2 2 CNH domain Coatomer_WDAD PF04053.14 KKK23222.1 - 0.006 15.7 0.0 0.036 13.1 0.0 2.1 2 1 0 2 2 2 1 Coatomer WD associated region Ge1_WD40 PF16529.5 KKK23222.1 - 0.18 10.8 0.0 0.6 9.0 0.0 1.9 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Pkinase PF00069.25 KKK23228.1 - 8.9e-19 67.9 0.0 1e-18 67.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK23228.1 - 4.3e-18 65.5 0.0 7.6e-18 64.7 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KKK23228.1 - 0.0096 15.3 0.2 0.013 14.8 0.2 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KKK23228.1 - 0.014 15.0 0.0 0.02 14.5 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Kinase-like PF14531.6 KKK23228.1 - 0.047 13.0 0.0 0.22 10.8 0.0 1.8 1 1 0 1 1 1 0 Kinase-like Pkinase_fungal PF17667.1 KKK23228.1 - 0.21 10.3 0.0 0.28 9.9 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase ArgJ PF01960.18 KKK23229.1 - 2.4e-148 493.9 0.1 2.7e-148 493.7 0.1 1.0 1 0 0 1 1 1 1 ArgJ family Ldh_1_C PF02866.18 KKK23229.1 - 0.12 12.3 0.2 0.23 11.4 0.2 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, alpha/beta C-terminal domain Pkinase PF00069.25 KKK23231.1 - 1.9e-23 83.2 0.0 7.2e-13 48.5 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KKK23231.1 - 9.7e-10 38.2 0.0 0.00027 20.3 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 KKK23231.1 - 0.00013 21.9 0.1 0.026 14.4 0.1 2.3 2 0 0 2 2 2 2 Phosphotransferase enzyme family zf-C2H2_6 PF13912.6 KKK23233.1 - 0.0064 16.5 1.6 0.047 13.7 0.1 2.8 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_4 PF13894.6 KKK23233.1 - 0.028 15.3 0.2 0.097 13.6 0.2 2.0 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2 PF00096.26 KKK23233.1 - 0.13 12.8 0.2 0.35 11.4 0.2 1.8 1 0 0 1 1 1 0 Zinc finger, C2H2 type APH PF01636.23 KKK23235.1 - 5.7e-12 46.1 0.0 3.1e-11 43.6 0.0 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KKK23235.1 - 0.00012 21.5 0.0 0.0011 18.3 0.0 2.3 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3435 PF11917.8 KKK23236.1 - 4.9e-17 62.0 0.2 7.6e-17 61.3 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) DUF1233 PF06806.12 KKK23236.1 - 0.05 13.2 0.0 0.095 12.3 0.0 1.4 1 0 0 1 1 1 0 Putative excisionase (DUF1233) TT_ORF2 PF02957.15 KKK23236.1 - 0.094 13.6 0.4 0.22 12.4 0.4 1.6 1 0 0 1 1 1 0 TT viral ORF2 APH PF01636.23 KKK23237.1 - 1.2e-11 45.0 0.0 6.3e-11 42.6 0.0 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KKK23237.1 - 0.068 12.5 0.0 9.4 5.5 0.0 2.3 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family MAP65_ASE1 PF03999.12 KKK23238.1 - 0.1 11.2 0.0 0.12 11.0 0.0 1.2 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Helo_like_N PF17111.5 KKK23239.1 - 0.11 11.9 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Fungal N-terminal domain of STAND proteins CDC45 PF02724.14 KKK23240.1 - 0.088 11.1 1.4 0.13 10.6 1.4 1.1 1 0 0 1 1 1 0 CDC45-like protein RXT2_N PF08595.11 KKK23240.1 - 0.19 11.7 1.2 0.33 11.0 1.2 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal Sigma70_ner PF04546.13 KKK23240.1 - 0.99 9.2 9.9 1.5 8.6 9.9 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region DNA_pol_phi PF04931.13 KKK23240.1 - 0.99 7.4 12.3 1.4 6.9 12.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi PBP1_TM PF14812.6 KKK23240.1 - 5.4 7.4 10.2 10 6.6 10.2 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PC4 PF02229.16 KKK23242.1 - 1.5e-23 82.2 0.1 2.6e-23 81.4 0.1 1.4 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) MIT PF04212.18 KKK23243.1 - 4.9e-12 45.7 2.2 1.3e-11 44.4 1.0 2.3 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain PXA PF02194.15 KKK23244.1 - 2.5e-32 112.3 0.2 7.2e-32 110.8 0.2 1.9 1 0 0 1 1 1 1 PXA domain Nexin_C PF08628.12 KKK23244.1 - 1.3e-22 80.5 0.0 6.7e-22 78.2 0.0 2.3 2 0 0 2 2 2 1 Sorting nexin C terminal PX PF00787.24 KKK23244.1 - 8.3e-09 35.4 0.0 1.3e-07 31.6 0.0 2.4 2 0 0 2 2 2 1 PX domain 4HBT PF03061.22 KKK23245.1 - 3e-10 40.3 0.1 4.2e-10 39.8 0.1 1.3 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.6 KKK23245.1 - 0.018 15.2 0.0 0.02 15.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4442) CH PF00307.31 KKK23246.1 - 8.6e-76 251.2 0.0 6.4e-21 74.6 0.0 4.1 4 0 0 4 4 4 4 Calponin homology (CH) domain EF-hand_7 PF13499.6 KKK23246.1 - 1.3e-07 32.0 1.6 1.3e-05 25.6 0.6 2.8 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 KKK23246.1 - 0.00021 20.9 3.9 0.029 14.3 0.1 3.2 3 0 0 3 3 3 2 EF-hand domain CAMSAP_CH PF11971.8 KKK23246.1 - 0.00044 20.0 0.0 0.21 11.4 0.0 3.6 4 0 0 4 4 4 1 CAMSAP CH domain EF-hand_1 PF00036.32 KKK23246.1 - 0.00069 19.0 1.4 0.75 9.5 0.1 3.4 3 0 0 3 3 3 2 EF hand EF-hand_5 PF13202.6 KKK23246.1 - 0.012 15.0 2.6 2 8.1 0.2 2.8 2 0 0 2 2 2 0 EF hand DDHD PF02862.17 KKK23247.1 - 3e-42 145.3 0.0 3e-42 145.3 0.0 2.5 2 1 0 2 2 2 1 DDHD domain WWE PF02825.20 KKK23247.1 - 0.032 14.8 3.7 0.9 10.2 1.6 3.4 2 1 0 2 2 2 0 WWE domain Usp PF00582.26 KKK23247.1 - 0.09 13.3 1.2 0.22 12.0 1.2 1.6 1 0 0 1 1 1 0 Universal stress protein family Lipase_3 PF01764.25 KKK23247.1 - 0.18 11.7 0.0 0.38 10.6 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) Ribosomal_L18 PF17135.4 KKK23248.1 - 1e-92 308.7 3.9 1.4e-92 308.3 3.9 1.2 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Mito_carr PF00153.27 KKK23248.1 - 8.8e-71 233.9 0.7 8.8e-23 80.0 0.0 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KKK23248.1 - 0.0013 17.9 0.3 0.036 13.2 0.0 3.0 2 1 1 3 3 3 1 Gammaproteobacterial serine protease Ribosomal_L27A PF00828.19 KKK23248.1 - 0.0013 19.4 0.0 0.0033 18.1 0.0 1.7 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A RRM_1 PF00076.22 KKK23249.1 - 8.4e-12 44.7 0.0 1.2e-11 44.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KKK23249.1 - 0.00058 19.8 0.0 0.00084 19.3 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Peptidase_M24 PF00557.24 KKK23250.1 - 1.3e-57 194.9 0.0 1.8e-57 194.4 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 KKK23250.1 - 2.4e-24 85.4 0.0 5.3e-24 84.3 0.0 1.5 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain RE_Bsp6I PF09504.10 KKK23251.1 - 0.063 12.9 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Bsp6I restriction endonuclease Tenui_NCP PF04876.12 KKK23251.1 - 0.18 11.4 0.2 0.42 10.2 0.1 1.6 2 0 0 2 2 2 0 Tenuivirus major non-capsid protein BTB PF00651.31 KKK23251.1 - 0.18 12.1 0.0 0.39 11.0 0.0 1.6 1 0 0 1 1 1 0 BTB/POZ domain Peptidase_M1 PF01433.20 KKK23252.1 - 5.4e-46 156.9 0.3 7.8e-46 156.4 0.3 1.2 1 0 0 1 1 1 1 Peptidase family M1 domain Leuk-A4-hydro_C PF09127.11 KKK23252.1 - 5.4e-37 126.3 0.0 1.3e-36 125.1 0.0 1.7 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1_N PF17900.1 KKK23252.1 - 3e-28 99.3 0.1 4.3e-28 98.8 0.1 1.2 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Peptidase_M61 PF05299.12 KKK23252.1 - 0.14 12.6 1.7 2.3 8.7 1.7 2.5 1 1 0 1 1 1 0 M61 glycyl aminopeptidase Ubiq_cyt_C_chap PF03981.12 KKK23253.1 - 1.7e-30 105.9 0.1 2.1e-30 105.6 0.1 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone Aldedh PF00171.22 KKK23254.1 - 8.2e-15 54.3 9.1 1.2e-09 37.3 7.1 2.9 2 1 0 2 2 2 2 Aldehyde dehydrogenase family PCI PF01399.27 KKK23255.1 - 0.0079 16.7 0.0 0.078 13.5 0.0 2.6 4 0 0 4 4 4 1 PCI domain TPR_1 PF00515.28 KKK23255.1 - 0.038 13.8 0.2 0.083 12.8 0.2 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.17 KKK23255.1 - 0.041 14.0 0.1 0.11 12.7 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat GST_C_2 PF13410.6 KKK23257.1 - 3.5e-18 65.4 0.0 5.3e-18 64.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KKK23257.1 - 1.4e-05 25.3 0.0 2.7e-05 24.3 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KKK23257.1 - 0.0015 18.6 0.0 0.0031 17.7 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 KKK23257.1 - 0.051 14.1 0.0 0.073 13.6 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Mito_carr PF00153.27 KKK23258.1 - 1.2e-68 227.1 3.4 7.2e-23 80.3 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_1 PF00036.32 KKK23258.1 - 7.5e-21 72.1 2.6 2.8e-06 26.5 0.1 3.6 3 0 0 3 3 3 3 EF hand EF-hand_5 PF13202.6 KKK23258.1 - 2.2e-19 68.0 3.3 3.9e-06 26.1 0.2 3.6 3 1 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 KKK23258.1 - 5.9e-18 65.1 2.2 1.4e-11 44.7 0.2 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KKK23258.1 - 9e-15 53.3 7.9 0.00024 20.8 0.0 4.0 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 KKK23258.1 - 3.4e-10 39.6 0.7 0.00018 21.3 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KKK23258.1 - 8.2e-07 29.3 0.0 0.0024 18.2 0.0 2.3 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.6 KKK23258.1 - 0.061 13.2 0.6 11 5.9 0.0 2.8 3 0 0 3 3 3 0 EF hand Cyclin_N PF00134.23 KKK23259.1 - 6.4e-11 42.1 0.0 1.3e-10 41.1 0.0 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C_2 PF16899.5 KKK23259.1 - 0.021 15.2 1.0 0.098 13.0 0.2 2.4 2 1 0 2 2 2 0 Cyclin C-terminal domain DUF4452 PF14618.6 KKK23260.1 - 4.1e-77 257.8 7.4 5.1e-77 257.5 7.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4452) SNARE PF05739.19 KKK23262.1 - 1e-08 35.0 0.9 1e-08 35.0 0.9 1.9 2 0 0 2 2 2 1 SNARE domain Use1 PF09753.9 KKK23262.1 - 8.2e-05 22.5 0.0 0.00018 21.3 0.0 1.5 1 1 0 1 1 1 1 Membrane fusion protein Use1 MDMPI_N PF11716.8 KKK23262.1 - 0.0068 17.1 0.1 0.018 15.7 0.1 1.7 1 0 0 1 1 1 1 Mycothiol maleylpyruvate isomerase N-terminal domain TPR_MLP1_2 PF07926.12 KKK23262.1 - 0.068 13.2 0.4 0.068 13.2 0.4 2.2 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF1664 PF07889.12 KKK23262.1 - 0.26 11.4 2.0 8.3 6.5 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Snapin_Pallidin PF14712.6 KKK23262.1 - 0.41 11.1 2.5 2.3 8.7 0.3 2.3 2 0 0 2 2 2 0 Snapin/Pallidin WXG100 PF06013.12 KKK23262.1 - 0.43 10.9 3.3 12 6.2 0.1 3.5 3 1 1 4 4 4 0 Proteins of 100 residues with WXG CENP-Q PF13094.6 KKK23262.1 - 2.1 8.5 8.2 0.78 9.9 0.3 2.6 2 2 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Golgin_A5 PF09787.9 KKK23262.1 - 2.3 7.6 6.4 1.2 8.5 0.5 2.1 2 0 0 2 2 2 0 Golgin subfamily A member 5 TolA_bind_tri PF16331.5 KKK23262.1 - 8.4 6.6 13.5 9.4 6.4 2.8 3.3 2 2 1 4 4 4 0 TolA binding protein trimerisation zf-TRAF PF02176.18 KKK23263.1 - 1.1e-11 45.2 10.0 2.1e-09 37.9 5.8 4.5 3 2 2 5 5 4 2 TRAF-type zinc finger zf-TRAF_2 PF15965.5 KKK23263.1 - 1.6e-07 31.7 5.8 1.6e-07 31.7 5.8 3.8 1 1 3 4 4 4 1 TRAF-like zinc-finger zf-C3HC4 PF00097.25 KKK23263.1 - 3.9e-07 29.8 11.9 3.9e-07 29.8 11.9 3.3 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KKK23263.1 - 7.3e-07 29.1 10.7 7.3e-07 29.1 10.7 2.7 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 KKK23263.1 - 3.9e-06 26.7 11.5 3.9e-06 26.7 11.5 3.4 3 1 0 3 3 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KKK23263.1 - 1.1e-05 25.5 12.1 1.1e-05 25.5 12.1 2.6 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 KKK23263.1 - 2.4e-05 24.6 13.0 2.4e-05 24.6 13.0 3.8 2 1 0 2 2 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 KKK23263.1 - 5.5e-05 23.0 10.0 5.5e-05 23.0 10.0 3.6 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) Sina PF03145.16 KKK23263.1 - 0.00025 21.1 15.4 0.0044 17.0 4.1 2.7 1 1 1 3 3 3 3 Seven in absentia protein family zf-C3HC4_2 PF13923.6 KKK23263.1 - 0.0011 18.7 12.5 0.0011 18.7 12.5 4.1 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 KKK23263.1 - 0.0054 16.5 1.7 0.0054 16.5 1.7 4.2 4 1 0 4 4 4 1 RING/Ubox like zinc-binding domain PilN PF05137.13 KKK23263.1 - 0.033 14.3 0.1 0.075 13.2 0.1 1.5 1 0 0 1 1 1 0 Fimbrial assembly protein (PilN) zf-ACC PF17848.1 KKK23263.1 - 0.037 14.1 0.1 0.037 14.1 0.1 3.8 4 0 0 4 4 4 0 Acetyl-coA carboxylase zinc finger domain AhpC-TSA_2 PF13911.6 KKK23283.1 - 6.6e-18 64.9 0.0 8.8e-18 64.5 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.21 KKK23283.1 - 0.0079 16.1 0.0 0.019 14.9 0.0 1.6 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KKK23283.1 - 0.12 12.1 0.0 0.21 11.3 0.0 1.5 1 1 0 1 1 1 0 Redoxin TNT PF14021.6 KKK23284.1 - 7.2e-32 109.8 0.0 1.1e-31 109.2 0.0 1.3 1 0 0 1 1 1 1 Tuberculosis necrotizing toxin Gln-synt_C PF00120.24 KKK23294.1 - 2.8e-82 276.5 0.0 3.3e-82 276.3 0.0 1.0 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Viral_alk_exo PF01771.17 KKK23294.1 - 0.28 10.0 0.0 0.49 9.2 0.0 1.3 1 0 0 1 1 1 0 Viral alkaline exonuclease Malate_synthase PF01274.22 KKK23295.1 - 7.8e-235 780.1 0.0 8.9e-235 779.9 0.0 1.0 1 0 0 1 1 1 1 Malate synthase Shikimate_dh_N PF08501.11 KKK23296.1 - 3.2e-24 85.0 0.0 5.5e-24 84.2 0.0 1.4 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.20 KKK23296.1 - 0.0003 20.8 0.0 0.00052 20.1 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase SDH_C PF18317.1 KKK23296.1 - 0.00081 19.1 0.0 0.0018 18.0 0.0 1.6 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain B12-binding PF02310.19 KKK23296.1 - 0.12 12.4 0.0 11 6.1 0.0 2.6 2 0 0 2 2 2 0 B12 binding domain PLA2_B PF01735.18 KKK23303.1 - 1.1e-194 647.4 1.2 1.3e-194 647.2 1.2 1.1 1 0 0 1 1 1 1 Lysophospholipase catalytic domain 7tm_4 PF13853.6 KKK23307.1 - 0.042 13.6 0.5 0.078 12.7 0.2 1.5 1 1 0 1 1 1 0 Olfactory receptor DUF1449 PF07290.11 KKK23307.1 - 0.098 12.3 2.0 0.081 12.5 1.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1449) MMPL PF03176.15 KKK23307.1 - 0.11 11.4 1.1 0.24 10.3 1.1 1.5 1 0 0 1 1 1 0 MMPL family GST_N_3 PF13417.6 KKK23308.1 - 4.1e-20 72.0 0.0 8e-20 71.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KKK23308.1 - 5.1e-18 65.1 0.0 1.2e-17 64.0 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KKK23308.1 - 1.6e-08 34.8 0.0 3.8e-08 33.6 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KKK23308.1 - 5.3e-07 29.6 0.3 1.2e-06 28.4 0.3 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 KKK23308.1 - 7.9e-06 26.4 0.0 1.6e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KKK23308.1 - 0.01 16.0 0.0 0.03 14.5 0.0 1.8 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 KKK23308.1 - 0.05 13.8 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 Glutaredoxin Zeta_toxin PF06414.12 KKK23308.1 - 0.072 12.4 0.0 0.21 10.9 0.0 1.8 1 0 0 1 1 1 0 Zeta toxin Cas_Cas02710 PF09670.10 KKK23308.1 - 0.076 11.8 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Cas02710) SUZ PF12752.7 KKK23309.1 - 5.2e-05 23.9 5.8 5.2e-05 23.9 5.8 4.7 2 1 1 3 3 3 1 SUZ domain Cation_ATPase_N PF00690.26 KKK23314.1 - 4.6e-09 35.8 4.6 2.5e-06 27.0 4.6 2.3 1 1 0 1 1 1 1 Cation transporter/ATPase, N-terminus E1-E2_ATPase PF00122.20 KKK23314.1 - 5.6e-07 29.3 1.1 8.1e-05 22.2 0.0 2.1 2 0 0 2 2 2 2 E1-E2 ATPase DctM PF06808.12 KKK23314.1 - 5.1e-05 22.3 0.3 5.8e-05 22.1 0.3 1.0 1 0 0 1 1 1 1 Tripartite ATP-independent periplasmic transporter, DctM component Phage_holin_3_5 PF16085.5 KKK23314.1 - 0.014 15.5 0.4 0.018 15.2 0.4 1.2 1 0 0 1 1 1 0 Bacteriophage holin Hol, superfamily III Glyco_hydro_28 PF00295.17 KKK23315.1 - 2.1e-55 188.1 5.8 2.8e-55 187.7 5.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 DUF4097 PF13349.6 KKK23315.1 - 0.0001 21.8 0.1 0.00017 21.0 0.1 1.4 1 0 0 1 1 1 1 Putative adhesin Beta_helix PF13229.6 KKK23315.1 - 0.00011 22.0 4.1 0.0018 18.2 2.6 2.3 1 1 1 2 2 2 2 Right handed beta helix region MmgE_PrpD PF03972.14 KKK23316.1 - 7.7e-146 486.1 0.0 9.3e-146 485.8 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family DUF1266 PF06889.11 KKK23316.1 - 0.029 14.4 0.0 0.53 10.3 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1266) Ubiquitin_2 PF14560.6 KKK23316.1 - 0.036 14.5 0.3 0.086 13.3 0.3 1.6 1 0 0 1 1 1 0 Ubiquitin-like domain DNA_methylase PF00145.17 KKK23317.1 - 7.6e-44 150.4 0.0 1.3e-31 110.2 0.0 2.2 1 1 1 2 2 2 2 C-5 cytosine-specific DNA methylase GATase_6 PF13522.6 KKK23318.1 - 2.3e-14 53.7 0.0 4.8e-14 52.7 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 KKK23318.1 - 7.7e-12 45.2 0.0 2.6e-11 43.5 0.0 1.9 2 0 0 2 2 2 1 Glutamine amidotransferase domain Pribosyltran PF00156.27 KKK23318.1 - 8e-07 28.7 0.0 1.8e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.6 KKK23318.1 - 5.3e-05 22.3 0.0 0.00011 21.2 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferases class-II PRTase_2 PF15609.6 KKK23318.1 - 0.05 13.1 0.0 0.14 11.7 0.0 1.7 1 1 0 1 1 1 0 Phosphoribosyl transferase DNA_photolyase PF00875.18 KKK23318.1 - 0.096 12.7 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 DNA photolyase Ribosomal_S17_N PF16205.5 KKK23319.1 - 1.4e-33 115.0 0.5 2.4e-33 114.3 0.5 1.4 1 0 0 1 1 1 1 Ribosomal_S17 N-terminal Ribosomal_S17 PF00366.20 KKK23319.1 - 7.7e-28 96.4 0.8 7.7e-28 96.4 0.8 1.6 2 0 0 2 2 2 1 Ribosomal protein S17 Spc7_N PF15402.6 KKK23320.1 - 0 1306.0 65.7 0 1305.5 65.7 1.2 1 0 0 1 1 1 1 N-terminus of kinetochore NMS complex subunit Spc7 Spc7 PF08317.11 KKK23320.1 - 4.2e-128 426.6 6.8 4.2e-128 426.6 6.8 1.6 2 0 0 2 2 2 1 Spc7 kinetochore protein Sec8_exocyst PF04048.14 KKK23320.1 - 0.0045 16.9 2.0 0.012 15.5 2.0 1.6 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain Gp_dh_C PF02800.20 KKK23320.1 - 0.081 12.5 0.0 0.25 10.9 0.0 1.8 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Exonuc_VII_L PF02601.15 KKK23320.1 - 8.6 5.8 9.9 0.25 10.9 2.0 2.2 2 0 0 2 2 2 0 Exonuclease VII, large subunit ANTH PF07651.16 KKK23321.1 - 3.7e-61 206.6 0.7 4.6e-61 206.3 0.7 1.1 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.20 KKK23321.1 - 1e-05 25.5 0.1 4.9e-05 23.4 0.0 2.0 2 0 0 2 2 2 1 ENTH domain Ribosomal_L24e PF01246.20 KKK23322.1 - 0.17 12.1 0.1 0.39 11.0 0.1 1.6 1 0 0 1 1 1 0 Ribosomal protein L24e DAGK_cat PF00781.24 KKK23324.1 - 4.4e-13 48.9 0.0 7.7e-13 48.2 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Mac_assoc PF16628.5 KKK23325.1 - 1.6e-86 289.3 5.9 1.6e-86 289.3 5.9 2.6 2 1 0 2 2 2 1 Unstructured region on maltose acetyltransferase Mac PF12464.8 KKK23325.1 - 5.6e-13 48.9 0.1 2.4e-12 46.9 0.0 2.1 2 0 0 2 2 2 1 Maltose acetyltransferase Hexapep PF00132.24 KKK23325.1 - 6.8e-10 38.3 1.4 0.00062 19.4 0.1 3.5 3 0 0 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Zn_clus PF00172.18 KKK23325.1 - 1.1e-09 38.2 8.4 2.2e-09 37.3 8.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Hexapep_2 PF14602.6 KKK23325.1 - 8.8e-09 35.0 2.3 1e-06 28.4 0.1 3.7 4 0 0 4 4 4 1 Hexapeptide repeat of succinyl-transferase ALAD PF00490.21 KKK23326.1 - 4.5e-103 344.7 0.0 7.3e-102 340.8 0.0 2.0 1 1 1 2 2 2 2 Delta-aminolevulinic acid dehydratase NUDIX PF00293.28 KKK23327.1 - 2e-17 63.5 0.0 3.1e-17 62.9 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain NUDIX PF00293.28 KKK23328.1 - 9.8e-07 28.9 0.0 1.6e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain zf-C3HC4_3 PF13920.6 KKK23329.1 - 2.4e-12 46.5 6.1 4.1e-12 45.8 6.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) EST1_DNA_bind PF10373.9 KKK23329.1 - 9e-07 28.6 0.1 1.4e-05 24.8 0.0 2.3 2 0 0 2 2 2 1 Est1 DNA/RNA binding domain zf-C3HC4 PF00097.25 KKK23329.1 - 5.3e-06 26.2 6.9 1e-05 25.3 6.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KKK23329.1 - 2.4e-05 24.6 7.4 4.4e-05 23.7 7.4 1.5 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 KKK23329.1 - 9.9e-05 22.1 7.2 0.00019 21.2 7.2 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KKK23329.1 - 0.00047 20.1 5.9 0.00091 19.1 5.9 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KKK23329.1 - 0.024 14.5 8.2 0.054 13.3 8.2 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KKK23329.1 - 0.19 11.8 7.7 0.052 13.6 3.7 2.2 1 1 1 2 2 2 0 RING-type zinc-finger zf-C3HC4_4 PF15227.6 KKK23329.1 - 0.65 10.2 6.8 1.4 9.1 6.8 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 KKK23329.1 - 0.82 9.5 5.7 1.6 8.6 5.7 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Glycos_transf_2 PF00535.26 KKK23330.1 - 3.1e-23 82.4 0.0 3.8e-22 78.9 0.0 2.3 1 1 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KKK23330.1 - 8.9e-06 25.7 0.0 0.01 15.8 0.0 2.9 3 0 0 3 3 3 2 Glycosyltransferase like family 2 Autophagy_N PF03986.13 KKK23333.1 - 1.2e-46 158.1 0.0 2.4e-46 157.1 0.0 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_C PF10381.9 KKK23333.1 - 8.5e-16 57.2 0.4 1.4e-15 56.5 0.4 1.3 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal Autophagy_act_C PF03987.15 KKK23333.1 - 5.1e-13 49.4 0.1 9.3e-13 48.6 0.1 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain CDC27 PF09507.10 KKK23333.1 - 0.11 11.8 0.9 0.19 11.1 0.9 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF1471 PF07338.13 KKK23333.1 - 0.13 12.2 0.6 0.3 11.1 0.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1471) Cyclin_N PF00134.23 KKK23334.1 - 0.0008 19.2 0.0 0.0044 16.8 0.0 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain TFIIB PF00382.19 KKK23334.1 - 0.0058 16.7 0.0 0.28 11.3 0.0 2.4 2 0 0 2 2 2 1 Transcription factor TFIIB repeat DUF812 PF05667.11 KKK23335.1 - 0.0036 16.3 2.4 0.0045 15.9 2.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) Exonuc_VII_L PF02601.15 KKK23335.1 - 0.13 11.8 4.1 0.19 11.3 4.1 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit HAUS5 PF14817.6 KKK23335.1 - 0.17 10.6 9.4 0.24 10.1 9.4 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 Glyco_H_20C_C PF18088.1 KKK23335.1 - 1.3 8.8 5.7 2.2 8.1 5.7 1.3 1 0 0 1 1 1 0 Glycoside Hydrolase 20C C-terminal domain Nup88 PF10168.9 KKK23335.1 - 1.3 6.7 6.5 1.9 6.2 6.5 1.1 1 0 0 1 1 1 0 Nuclear pore component EMP24_GP25L PF01105.24 KKK23365.1 - 1.9e-49 168.1 0.5 2.2e-49 167.9 0.5 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD CENP-F_leu_zip PF10473.9 KKK23375.1 - 0.0093 16.0 6.7 0.0093 16.0 6.7 3.2 1 1 1 3 3 3 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FlaC_arch PF05377.11 KKK23375.1 - 0.71 10.3 8.8 14 6.1 0.5 3.8 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Cnn_1N PF07989.11 KKK23375.1 - 2 8.6 19.6 0.056 13.6 3.7 3.4 3 1 0 3 3 3 0 Centrosomin N-terminal motif 1 DUF3450 PF11932.8 KKK23375.1 - 2.4 7.4 19.3 0.13 11.5 4.2 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) ATG16 PF08614.11 KKK23375.1 - 2.8 8.1 26.6 0.14 12.4 9.2 3.0 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) GAS PF13851.6 KKK23375.1 - 3.8 6.8 24.0 2.9 7.2 7.3 2.9 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding BRE1 PF08647.11 KKK23375.1 - 4.3 7.5 19.6 0.3 11.2 7.3 2.7 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase Fib_alpha PF08702.10 KKK23375.1 - 6.5 6.9 13.0 1.7 8.8 2.5 2.8 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF2570 PF10828.8 KKK23375.1 - 7.9 6.4 12.0 8.8 6.2 6.5 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2570) Sel1 PF08238.12 KKK23380.1 - 4.2e-34 116.2 39.1 1.6e-05 25.4 0.1 11.5 12 1 0 12 12 12 8 Sel1 repeat TPR_16 PF13432.6 KKK23380.1 - 0.00049 20.7 10.3 6.1 7.6 0.2 5.8 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 KKK23380.1 - 0.024 14.8 7.5 28 5.2 0.1 6.3 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.6 KKK23380.1 - 0.11 13.4 0.3 15 6.7 0.2 4.6 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 KKK23380.1 - 3.4 7.9 11.2 9.6 6.5 0.1 5.2 7 0 0 7 7 7 0 Tetratricopeptide repeat Mei5 PF10376.9 KKK23381.1 - 0.0015 18.4 8.2 0.0041 17.0 2.5 2.2 1 1 1 2 2 2 2 Double-strand recombination repair protein Lectin_N PF03954.14 KKK23381.1 - 0.0076 16.0 1.3 0.09 12.5 1.3 2.1 1 1 0 1 1 1 1 Hepatic lectin, N-terminal domain GTP-bdg_M PF16360.5 KKK23381.1 - 0.025 15.2 4.1 0.16 12.6 0.1 2.5 2 1 0 2 2 2 0 GTP-binding GTPase Middle Region Mut7-C PF01927.16 KKK23381.1 - 0.047 13.8 0.6 0.57 10.3 0.0 2.2 2 0 0 2 2 2 0 Mut7-C RNAse domain Nas2_N PF18265.1 KKK23381.1 - 1.1 9.2 3.7 12 5.9 0.1 2.4 2 0 0 2 2 2 0 Nas2 N_terminal domain DUF1192 PF06698.11 KKK23381.1 - 1.8 8.7 8.7 6.8 6.8 0.6 3.3 3 1 1 4 4 4 0 Protein of unknown function (DUF1192) Snapin_Pallidin PF14712.6 KKK23381.1 - 1.9 9.0 6.9 3.7 8.0 4.9 2.3 2 1 1 3 3 3 0 Snapin/Pallidin OmpH PF03938.14 KKK23381.1 - 2.6 8.4 8.9 36 4.7 8.9 2.2 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) CALM_bind PF16025.5 KKK23381.1 - 3 8.4 6.4 1.8 9.1 4.5 1.7 2 1 0 2 2 2 0 Calcium-dependent calmodulin binding WD40 PF00400.32 KKK23382.1 - 2.2e-13 50.4 9.2 0.00017 22.3 0.0 5.2 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKK23382.1 - 4e-07 30.2 0.8 0.0075 16.5 0.0 3.9 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Mesothelin PF06060.12 KKK23382.1 - 0.19 9.9 0.1 0.24 9.5 0.1 1.1 1 0 0 1 1 1 0 Pre-pro-megakaryocyte potentiating factor precursor (Mesothelin) RNA_pol_Rpb1_1 PF04997.12 KKK23383.1 - 1.9e-114 382.2 0.0 3e-114 381.6 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 KKK23383.1 - 1.9e-85 286.6 0.0 5.1e-85 285.1 0.0 1.8 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 KKK23383.1 - 2.7e-77 258.6 0.0 6.6e-77 257.4 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.14 KKK23383.1 - 8.1e-65 218.2 1.5 1.6e-64 217.3 1.5 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.18 KKK23383.1 - 5.2e-46 156.4 0.0 1.4e-45 155.1 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.12 KKK23383.1 - 2.1e-44 150.8 9.1 2.3e-44 150.6 7.4 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.17 KKK23383.1 - 4.4e-37 126.3 0.1 1e-36 125.1 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.13 KKK23383.1 - 7.8e-21 73.3 194.3 0.0015 18.8 0.1 14.5 11 2 2 13 13 13 13 RNA polymerase Rpb1 C-terminal repeat Kelch_4 PF13418.6 KKK23384.1 - 6e-22 77.4 7.7 7.9e-08 32.2 0.0 5.0 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_6 PF13964.6 KKK23384.1 - 3e-21 74.9 1.1 3.7e-05 23.8 0.0 5.0 3 1 1 4 4 4 4 Kelch motif Kelch_5 PF13854.6 KKK23384.1 - 8.5e-21 73.5 0.6 1.2e-05 25.2 0.1 5.2 5 0 0 5 5 5 4 Kelch motif Kelch_3 PF13415.6 KKK23384.1 - 2.7e-18 65.8 2.6 3.8e-07 30.2 0.1 5.1 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_1 PF01344.25 KKK23384.1 - 4.2e-17 61.5 0.1 8.5e-05 22.1 0.0 4.2 4 0 0 4 4 4 3 Kelch motif Kelch_2 PF07646.15 KKK23384.1 - 4.5e-17 61.3 0.2 5e-05 23.1 0.0 4.4 4 0 0 4 4 4 3 Kelch motif BTB PF00651.31 KKK23384.1 - 3.1e-09 37.1 0.0 6e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.15 KKK23384.1 - 0.049 13.7 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 BTB And C-terminal Kelch ANAPC4_WD40 PF12894.7 KKK23385.1 - 4.2e-17 62.2 2.5 1.2e-05 25.5 0.1 4.3 2 1 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KKK23385.1 - 9.4e-16 57.9 17.6 5.1e-05 24.0 0.0 6.4 7 0 0 7 7 7 5 WD domain, G-beta repeat Ge1_WD40 PF16529.5 KKK23385.1 - 2.6e-06 26.6 0.0 0.00086 18.4 0.0 3.1 2 1 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KKK23385.1 - 0.00011 22.1 0.2 0.0079 16.1 0.1 2.5 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A Amidase PF01425.21 KKK23386.1 - 3.6e-09 36.1 0.0 2.2e-08 33.5 0.0 1.9 1 1 0 1 1 1 1 Amidase Glyco_hydro_1 PF00232.18 KKK23387.1 - 2.1e-145 484.6 0.0 2.5e-145 484.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 AID PF18767.1 KKK23387.1 - 0.0063 16.5 0.0 0.013 15.5 0.0 1.5 1 0 0 1 1 1 1 Activation induced deaminase Glyco_hydro_43 PF04616.14 KKK23390.1 - 5.9e-28 98.0 1.7 1e-27 97.2 1.7 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GARS_C PF02843.16 KKK23391.1 - 0.16 12.2 0.0 0.43 10.9 0.0 1.7 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, C domain ANAPC1 PF12859.7 KKK23392.1 - 1.1e-32 113.3 1.0 4.2e-32 111.4 1.0 2.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 1 PC_rep PF01851.22 KKK23392.1 - 0.34 11.4 0.0 0.34 11.4 0.0 4.2 5 0 0 5 5 5 0 Proteasome/cyclosome repeat Glyco_transf_8 PF01501.20 KKK23393.1 - 2.3e-08 33.9 0.0 2.8e-08 33.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 8 Glyco_transf_24 PF18404.1 KKK23393.1 - 0.016 14.7 0.0 0.018 14.5 0.0 1.1 1 0 0 1 1 1 0 Glucosyltransferase 24 Mannosyl_trans3 PF11051.8 KKK23393.1 - 0.22 10.8 0.0 0.28 10.5 0.0 1.1 1 0 0 1 1 1 0 Mannosyltransferase putative Glyco_hydro_18 PF00704.28 KKK23394.1 - 2.4e-33 116.2 0.0 2.8e-33 116.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 KKK23394.1 - 1.5e-09 38.2 33.3 2.2e-09 37.6 8.2 3.0 2 1 0 2 2 2 2 Chitin recognition protein VirE1 PF12189.8 KKK23394.1 - 0.15 12.2 0.0 0.27 11.4 0.0 1.3 1 0 0 1 1 1 0 Single-strand DNA-binding protein RPAP1_C PF08620.10 KKK23395.1 - 2.5e-24 85.2 0.0 4.2e-24 84.4 0.0 1.4 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.10 KKK23395.1 - 2.3e-16 59.3 6.4 2.3e-16 59.3 6.4 1.7 2 0 0 2 2 2 1 RPAP1-like, N-terminal ASD2 PF08687.11 KKK23395.1 - 0.027 14.0 2.1 0.053 13.1 2.1 1.4 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 HUN PF08729.10 KKK23396.1 - 1.4e-07 31.4 0.2 1.4e-07 31.4 0.2 1.9 2 0 0 2 2 2 1 HPC2 and ubinuclein domain Roughex PF06020.11 KKK23396.1 - 2 7.5 14.6 3.9 6.5 14.6 1.5 1 0 0 1 1 1 0 Drosophila roughex protein Apt1 PF10351.9 KKK23396.1 - 3.3 6.4 11.0 6.2 5.6 11.0 1.4 1 0 0 1 1 1 0 Golgi-body localisation protein domain Pyr_redox_3 PF13738.6 KKK23397.1 - 1.1e-12 47.9 0.0 1.8e-12 47.2 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KKK23397.1 - 8.5e-12 44.9 0.0 8.3e-10 38.3 0.0 2.1 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 KKK23397.1 - 2.5e-09 36.8 0.0 3.3e-09 36.4 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KKK23397.1 - 4.2e-09 35.4 0.0 5.6e-09 35.0 0.0 1.1 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 KKK23397.1 - 0.00073 19.7 0.0 0.0024 18.1 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KKK23397.1 - 0.0039 16.5 0.1 0.0083 15.4 0.1 1.5 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.6 KKK23397.1 - 0.089 12.8 0.2 0.66 9.9 0.0 2.5 2 1 0 2 2 2 0 FAD-NAD(P)-binding PMP1_2 PF08114.11 KKK23399.1 - 0.26 11.1 4.2 1.1 9.1 0.4 2.9 2 0 0 2 2 2 0 ATPase proteolipid family MFS_1 PF07690.16 KKK23400.1 - 1.7e-29 102.9 39.2 1.7e-29 102.9 39.2 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily DPM2 PF07297.12 KKK23400.1 - 0.017 15.4 0.1 0.12 12.7 0.1 2.6 1 0 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) MFS_4 PF06779.14 KKK23400.1 - 0.29 10.4 20.4 0.066 12.5 6.3 2.4 2 1 0 2 2 2 0 Uncharacterised MFS-type transporter YbfB Peptidase_S10 PF00450.22 KKK23401.1 - 1e-110 371.1 0.3 1.2e-110 370.8 0.3 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase UNC-93 PF05978.16 KKK23402.1 - 1.5e-10 41.0 6.7 1.5e-10 41.0 6.7 3.5 4 0 0 4 4 4 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 KKK23402.1 - 1.7e-10 40.4 36.7 1.7e-10 40.4 36.7 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily SPC12 PF06645.13 KKK23402.1 - 5.9 7.1 9.1 1.2 9.3 1.1 3.7 3 0 0 3 3 3 0 Microsomal signal peptidase 12 kDa subunit (SPC12) Amidohydro_1 PF01979.20 KKK23403.1 - 5.8e-17 62.0 0.0 1.4e-16 60.8 0.0 1.5 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KKK23403.1 - 3.9e-13 49.7 0.2 3.2e-09 36.8 0.1 2.3 2 0 0 2 2 2 2 Amidohydrolase family Pam17 PF08566.10 KKK23405.1 - 2.4e-55 186.8 2.9 1.6e-51 174.4 0.0 2.6 2 1 1 3 3 3 2 Mitochondrial import protein Pam17 DUF2890 PF11081.8 KKK23405.1 - 0.011 15.8 0.0 0.019 15.1 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2890) Far-17a_AIG1 PF04750.14 KKK23406.1 - 6.8e-54 182.3 10.0 7.4e-54 182.1 10.0 1.0 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein Ank_2 PF12796.7 KKK23411.1 - 9.6e-30 103.0 8.5 9.1e-11 42.2 0.1 4.5 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KKK23411.1 - 3.9e-22 78.3 9.2 6.5e-08 33.0 0.1 5.8 1 1 4 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 KKK23411.1 - 1e-17 62.4 3.4 0.008 16.6 0.0 6.8 7 0 0 7 7 7 4 Ankyrin repeat Ank_5 PF13857.6 KKK23411.1 - 7.2e-17 61.2 5.1 0.00083 19.6 0.1 5.6 2 2 4 6 6 6 4 Ankyrin repeats (many copies) SPX PF03105.19 KKK23411.1 - 4.2e-16 59.8 12.0 1.1e-05 25.6 3.2 3.2 1 1 2 3 3 3 3 SPX domain Ank PF00023.30 KKK23411.1 - 3.4e-12 46.2 7.7 0.013 15.9 0.0 6.4 7 0 0 7 7 7 4 Ankyrin repeat GDPD PF03009.17 KKK23411.1 - 2.6e-09 37.2 0.0 6.4e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family APH PF01636.23 KKK23418.1 - 4.4e-15 56.3 1.4 1e-14 55.0 0.1 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.14 KKK23418.1 - 0.016 14.5 0.0 0.026 13.8 0.0 1.3 1 0 0 1 1 1 0 Fructosamine kinase DUF155 PF02582.14 KKK23419.1 - 7.1e-52 176.1 0.1 1.1e-51 175.5 0.1 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 UPF0449 PF15136.6 KKK23419.1 - 0.007 16.8 0.1 0.15 12.5 0.0 2.6 2 0 0 2 2 2 1 Uncharacterised protein family UPF0449 DUF2486 PF10667.9 KKK23419.1 - 4 7.6 8.2 2.2 8.4 2.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2486) U3_snoRNA_assoc PF08297.11 KKK23420.1 - 2.5e-21 76.2 1.6 2.5e-21 76.2 1.6 3.5 3 0 0 3 3 3 1 U3 snoRNA associated Asp-B-Hydro_N PF05279.11 KKK23420.1 - 1.1 9.2 15.1 1.7 8.6 15.1 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region PRCC PF10253.9 KKK23421.1 - 3.6e-35 122.7 9.2 3.6e-35 122.7 9.2 3.6 2 2 0 2 2 2 1 Mitotic checkpoint regulator, MAD2B-interacting PRIMA1 PF16101.5 KKK23421.1 - 0.064 13.3 5.8 0.15 12.1 5.8 1.6 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Cwf_Cwc_15 PF04889.12 KKK23421.1 - 0.11 12.2 3.3 0.26 11.0 3.1 1.8 1 1 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CAP_N PF01213.19 KKK23421.1 - 9.4 5.6 18.9 0.34 10.3 10.3 2.5 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal CTK3 PF12243.8 KKK23422.1 - 6.1e-53 178.0 0.1 8.6e-53 177.6 0.1 1.2 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 CTK3_C PF12350.8 KKK23422.1 - 6.6e-19 67.8 8.1 6.6e-19 67.8 8.1 2.2 3 0 0 3 3 3 1 CTD kinase subunit gamma CTK3 C-terminus DUF3873 PF12989.7 KKK23422.1 - 0.047 14.1 0.0 0.097 13.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF3873) adh_short PF00106.25 KKK23423.1 - 6.3e-40 136.7 0.7 8.4e-40 136.3 0.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KKK23423.1 - 2.7e-31 109.0 0.3 3.4e-31 108.6 0.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 KKK23423.1 - 1.7e-08 34.6 0.0 3.2e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KKK23423.1 - 0.00023 20.7 0.0 0.00035 20.1 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KKK23423.1 - 0.023 14.2 0.0 0.038 13.6 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family DER1 PF04511.15 KKK23423.1 - 0.042 13.8 0.0 0.071 13.0 0.0 1.4 1 0 0 1 1 1 0 Der1-like family RmlD_sub_bind PF04321.17 KKK23423.1 - 0.058 12.5 0.0 0.089 11.9 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain PAE PF03283.13 KKK23423.1 - 0.068 12.3 0.1 0.096 11.8 0.1 1.2 1 0 0 1 1 1 0 Pectinacetylesterase TadZ_N PF16968.5 KKK23423.1 - 0.078 12.7 0.4 0.14 11.8 0.4 1.3 1 0 0 1 1 1 0 Pilus assembly protein TadZ N-terminal GDP_Man_Dehyd PF16363.5 KKK23423.1 - 0.17 11.2 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase AAA_5 PF07728.14 KKK23424.1 - 1.7e-120 397.4 0.6 7.5e-22 77.8 0.0 9.0 7 1 1 8 8 8 8 AAA domain (dynein-related subfamily) AAA_lid_7 PF17867.1 KKK23424.1 - 2.5e-49 165.9 7.9 5.7e-20 71.5 0.0 5.5 5 0 0 5 5 4 3 Midasin AAA lid domain AAA_lid_5 PF17865.1 KKK23424.1 - 4.2e-31 107.2 0.9 2.4e-30 104.7 0.0 3.0 4 0 0 4 4 1 1 Midasin AAA lid domain AAA_3 PF07726.11 KKK23424.1 - 3e-27 95.1 0.0 1.1e-10 41.5 0.0 6.7 7 0 0 7 7 6 3 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 KKK23424.1 - 3.9e-24 85.1 3.4 9.4e-05 22.0 0.0 6.4 6 0 0 6 6 6 5 P-loop containing dynein motor region Dynein_heavy PF03028.15 KKK23424.1 - 3.2e-22 78.9 0.0 7.7e-06 26.0 0.0 7.9 8 0 0 8 8 7 4 Dynein heavy chain region D6 P-loop domain AAA_16 PF13191.6 KKK23424.1 - 4.5e-21 76.0 10.9 0.00024 21.5 0.3 7.6 5 2 0 5 5 5 4 AAA ATPase domain AAA PF00004.29 KKK23424.1 - 5.6e-21 75.3 0.0 4.3e-05 23.9 0.0 6.3 5 0 0 5 5 5 4 ATPase family associated with various cellular activities (AAA) AAA_6 PF12774.7 KKK23424.1 - 7.1e-16 58.1 0.0 0.024 13.6 0.1 7.0 7 0 0 7 7 6 4 Hydrolytic ATP binding site of dynein motor region AAA_30 PF13604.6 KKK23424.1 - 3.1e-15 56.4 0.0 0.0027 17.5 0.0 6.7 6 1 0 6 6 5 3 AAA domain Sigma54_activat PF00158.26 KKK23424.1 - 1e-14 54.6 0.0 0.009 15.7 0.1 5.6 5 0 0 5 5 5 3 Sigma-54 interaction domain AAA_14 PF13173.6 KKK23424.1 - 6.5e-14 52.1 0.0 0.0072 16.4 0.0 6.5 7 0 0 7 7 5 2 AAA domain TsaE PF02367.17 KKK23424.1 - 1.2e-12 47.9 2.1 0.055 13.5 0.0 5.5 5 0 0 5 5 5 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 KKK23424.1 - 1e-11 45.2 0.2 0.021 15.0 0.0 7.0 8 0 0 8 8 6 2 AAA domain AAA_22 PF13401.6 KKK23424.1 - 2.4e-11 44.1 2.6 0.066 13.5 0.0 7.0 7 0 0 7 7 5 3 AAA domain AAA_18 PF13238.6 KKK23424.1 - 5.2e-11 43.2 0.3 0.13 12.8 0.0 6.5 5 0 0 5 5 5 1 AAA domain ABC_tran PF00005.27 KKK23424.1 - 7.7e-11 42.7 1.9 0.046 14.2 0.0 6.0 6 0 0 6 6 6 2 ABC transporter Mg_chelatase PF01078.21 KKK23424.1 - 1.1e-10 41.3 1.5 3.7 6.9 0.1 8.2 8 1 0 8 8 8 0 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.12 KKK23424.1 - 2e-10 40.3 1.1 1.5 8.1 0.0 6.5 7 0 0 7 7 5 1 Zeta toxin Sigma54_activ_2 PF14532.6 KKK23424.1 - 2.1e-10 40.8 0.5 0.0015 18.6 0.1 5.4 5 0 0 5 5 4 2 Sigma-54 interaction domain RuvB_N PF05496.12 KKK23424.1 - 3.6e-10 39.8 2.5 0.079 12.7 0.0 6.2 6 0 0 6 6 6 2 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 KKK23424.1 - 6.4e-09 36.2 0.5 1.3 9.5 0.0 5.7 5 0 0 5 5 5 2 RNA helicase NACHT PF05729.12 KKK23424.1 - 8.6e-09 35.5 1.6 0.11 12.4 0.1 4.3 3 0 0 3 3 3 2 NACHT domain T2SSE PF00437.20 KKK23424.1 - 5.3e-08 32.2 3.5 0.22 10.6 0.0 5.4 5 0 0 5 5 5 1 Type II/IV secretion system protein DUF815 PF05673.13 KKK23424.1 - 8.7e-08 31.6 1.0 0.26 10.4 0.1 4.8 5 0 0 5 5 5 2 Protein of unknown function (DUF815) MMR_HSR1 PF01926.23 KKK23424.1 - 2e-07 31.1 0.8 0.18 11.9 0.0 5.5 5 0 0 5 5 5 1 50S ribosome-binding GTPase AAA_29 PF13555.6 KKK23424.1 - 3.1e-07 30.0 1.3 1.9 8.3 0.0 5.6 5 0 0 5 5 5 1 P-loop containing region of AAA domain AAA_19 PF13245.6 KKK23424.1 - 3.5e-07 30.7 8.5 0.74 10.1 0.2 6.4 7 0 0 7 7 4 2 AAA domain MCM PF00493.23 KKK23424.1 - 7.5e-07 28.5 0.0 0.74 8.9 0.0 5.0 5 0 0 5 5 5 2 MCM P-loop domain RsgA_GTPase PF03193.16 KKK23424.1 - 1.2e-06 28.5 1.9 0.18 11.7 0.1 5.3 5 0 0 5 5 5 1 RsgA GTPase TniB PF05621.11 KKK23424.1 - 1.3e-06 28.0 4.0 0.62 9.5 0.0 6.2 7 0 0 7 7 6 1 Bacterial TniB protein PduV-EutP PF10662.9 KKK23424.1 - 1.5e-06 28.0 2.9 0.061 13.1 0.0 5.1 6 0 0 6 6 5 1 Ethanolamine utilisation - propanediol utilisation Bac_DnaA PF00308.18 KKK23424.1 - 4e-06 26.8 0.1 0.39 10.5 0.0 3.7 3 0 0 3 3 3 1 Bacterial dnaA protein AAA_25 PF13481.6 KKK23424.1 - 4.8e-06 26.3 3.1 2.3 7.8 0.2 5.4 5 1 0 5 5 4 1 AAA domain Rad17 PF03215.15 KKK23424.1 - 7.3e-06 26.0 0.4 6.5 6.6 0.0 4.7 4 0 0 4 4 4 0 Rad17 P-loop domain ATPase_2 PF01637.18 KKK23424.1 - 7.9e-06 25.9 0.0 17 5.2 0.0 5.5 5 0 0 5 5 5 0 ATPase domain predominantly from Archaea SRP54 PF00448.22 KKK23424.1 - 1.5e-05 24.7 4.6 0.13 11.8 0.2 4.9 5 0 0 5 5 5 1 SRP54-type protein, GTPase domain IstB_IS21 PF01695.17 KKK23424.1 - 2.3e-05 24.2 0.0 4.9 6.9 0.0 4.6 4 0 0 4 4 4 0 IstB-like ATP binding protein Roc PF08477.13 KKK23424.1 - 2.7e-05 24.4 2.1 6.3 7.0 0.1 5.4 5 0 0 5 5 5 0 Ras of Complex, Roc, domain of DAPkinase AAA_9 PF12781.7 KKK23424.1 - 3.2e-05 23.1 0.0 0.45 9.6 0.0 4.0 4 0 0 4 4 4 2 ATP-binding dynein motor region AAA_28 PF13521.6 KKK23424.1 - 4.6e-05 23.7 1.3 4.9 7.4 0.1 5.1 5 0 0 5 5 4 0 AAA domain AAA_24 PF13479.6 KKK23424.1 - 8.2e-05 22.4 0.1 1.6 8.4 0.0 5.2 6 0 0 6 6 4 1 AAA domain NTPase_1 PF03266.15 KKK23424.1 - 0.00013 21.9 4.4 0.53 10.2 0.1 4.2 4 0 0 4 4 3 1 NTPase SRPRB PF09439.10 KKK23424.1 - 0.00018 21.0 1.0 4.5 6.7 0.0 4.7 5 0 0 5 5 4 0 Signal recognition particle receptor beta subunit TIP49 PF06068.13 KKK23424.1 - 0.00022 20.5 4.2 0.15 11.3 0.0 5.1 6 0 0 6 6 6 1 TIP49 P-loop domain ATP_bind_1 PF03029.17 KKK23424.1 - 0.00025 20.9 1.4 2.8 7.6 0.0 4.6 4 0 0 4 4 4 1 Conserved hypothetical ATP binding protein CPT PF07931.12 KKK23424.1 - 0.00076 19.4 0.3 3.5 7.4 0.0 4.9 5 1 0 5 5 3 0 Chloramphenicol phosphotransferase-like protein ResIII PF04851.15 KKK23424.1 - 0.001 19.1 0.7 5.9 6.9 0.2 4.2 4 0 0 4 4 3 0 Type III restriction enzyme, res subunit AAA_8 PF12780.7 KKK23424.1 - 0.0047 16.3 0.3 2.3 7.5 0.0 4.3 5 0 0 5 5 4 1 P-loop containing dynein motor region D4 FeoB_N PF02421.18 KKK23424.1 - 0.0054 16.3 2.5 2.5 7.6 0.0 4.5 5 0 0 5 5 4 1 Ferrous iron transport protein B CbiA PF01656.23 KKK23424.1 - 0.0055 16.8 0.0 4 7.5 0.0 3.6 3 0 0 3 3 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain NB-ARC PF00931.22 KKK23424.1 - 0.008 15.4 0.9 16 4.6 0.1 4.1 4 0 0 4 4 4 0 NB-ARC domain DAP3 PF10236.9 KKK23424.1 - 0.013 14.7 1.6 6.4 5.9 0.2 3.8 4 0 0 4 4 4 0 Mitochondrial ribosomal death-associated protein 3 ATPase PF06745.13 KKK23424.1 - 0.019 14.3 0.3 37 3.6 0.0 4.0 4 0 0 4 4 4 0 KaiC MeaB PF03308.16 KKK23424.1 - 0.03 13.3 6.2 0.38 9.7 0.4 3.7 4 0 0 4 4 4 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Viral_helicase1 PF01443.18 KKK23424.1 - 0.12 12.1 0.0 22 4.7 0.0 3.8 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase Thymidylate_kin PF02223.17 KKK23424.1 - 0.12 12.0 0.6 64 3.2 0.0 4.5 4 0 0 4 4 4 0 Thymidylate kinase KTI12 PF08433.10 KKK23424.1 - 0.13 11.7 0.8 25 4.2 0.0 4.2 4 0 0 4 4 3 0 Chromatin associated protein KTI12 DnaB_C PF03796.15 KKK23424.1 - 0.72 9.1 5.7 2 7.7 0.0 3.8 4 0 0 4 4 3 0 DnaB-like helicase C terminal domain MobB PF03205.14 KKK23424.1 - 0.81 9.6 5.8 26 4.7 0.2 4.8 5 0 0 5 5 5 0 Molybdopterin guanine dinucleotide synthesis protein B Voltage_CLC PF00654.20 KKK23425.1 - 7.9e-76 255.6 22.6 7.9e-76 255.6 22.6 1.6 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 KKK23425.1 - 0.00017 21.9 0.1 0.71 10.4 0.0 2.5 2 0 0 2 2 2 2 CBS domain XLF PF09302.11 KKK23426.1 - 4.1e-51 173.7 1.1 4.1e-51 173.7 1.1 1.9 2 0 0 2 2 2 1 XLF-Cernunnos, XRcc4-like factor, NHEJ component 4HBT PF03061.22 KKK23436.1 - 8.3e-15 54.9 0.1 1.2e-14 54.4 0.1 1.2 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.6 KKK23436.1 - 0.0067 16.6 0.0 0.0098 16.0 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4442) 4HBT_3 PF13622.6 KKK23436.1 - 0.071 13.4 0.0 0.073 13.3 0.0 1.1 1 0 0 1 1 1 0 Thioesterase-like superfamily Tfb2 PF03849.14 KKK23437.1 - 3.9e-136 453.7 0.0 5.5e-136 453.2 0.0 1.2 1 0 0 1 1 1 1 Transcription factor Tfb2 Tfb2_C PF18307.1 KKK23437.1 - 2.5e-24 85.4 0.2 5.1e-24 84.5 0.2 1.5 1 0 0 1 1 1 1 Transcription factor Tfb2 (p52) C-terminal domain Helicase_C_3 PF13625.6 KKK23437.1 - 2.4e-05 24.5 0.0 7.4e-05 22.9 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain NicO PF03824.16 KKK23438.1 - 0.29 10.4 3.9 0.42 9.9 3.9 1.1 1 0 0 1 1 1 0 High-affinity nickel-transport protein PhzC-PhzF PF02567.16 KKK23439.1 - 7.4e-15 55.2 0.1 6e-11 42.3 0.0 2.1 2 0 0 2 2 2 2 Phenazine biosynthesis-like protein TIMELESS_C PF05029.13 KKK23440.1 - 1.7e-87 294.9 35.4 5.9e-65 220.5 0.0 4.2 2 1 2 4 4 4 4 Timeless protein C terminal region TIMELESS PF04821.14 KKK23440.1 - 2.9e-87 292.5 1.1 3.3e-87 292.3 0.0 1.7 2 0 0 2 2 2 1 Timeless protein 3HCDH_N PF02737.18 KKK23441.1 - 1.4e-51 174.9 1.0 2e-51 174.4 1.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 KKK23441.1 - 7.9e-34 116.2 0.0 2e-33 114.8 0.0 1.7 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 KKK23441.1 - 0.00057 20.1 0.2 0.0014 18.9 0.2 1.6 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Sacchrp_dh_NADP PF03435.18 KKK23441.1 - 0.0095 16.2 0.4 0.02 15.2 0.4 1.6 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Pyr_redox_2 PF07992.14 KKK23441.1 - 0.017 14.4 0.0 0.022 14.0 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KKK23441.1 - 0.017 14.7 0.1 0.024 14.2 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase UDPG_MGDP_dh_N PF03721.14 KKK23441.1 - 0.03 13.9 0.0 0.044 13.4 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.19 KKK23441.1 - 0.12 11.7 0.2 0.32 10.3 0.1 1.7 1 1 1 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Actin PF00022.19 KKK23442.1 - 2.1e-112 375.7 0.0 1e-111 373.4 0.0 1.8 1 1 0 1 1 1 1 Actin Aquarius_N PF16399.5 KKK23443.1 - 0 1103.0 0.0 0 1102.7 0.0 1.1 1 0 0 1 1 1 1 Intron-binding protein aquarius N-terminus AAA_12 PF13087.6 KKK23443.1 - 4.3e-27 95.0 0.0 7.7e-27 94.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KKK23443.1 - 1.5e-21 77.4 0.0 4.2e-21 75.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KKK23443.1 - 5.8e-07 29.4 0.0 0.00034 20.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain ResIII PF04851.15 KKK23443.1 - 4.1e-06 26.9 0.0 9.6e-06 25.7 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 KKK23443.1 - 1.4e-05 25.5 0.0 3.7e-05 24.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 KKK23443.1 - 0.0003 20.6 0.1 0.11 12.2 0.0 3.4 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase DnaB_C PF03796.15 KKK23443.1 - 0.00033 20.1 0.1 0.013 14.9 0.0 2.8 3 0 0 3 3 3 1 DnaB-like helicase C terminal domain AAA_16 PF13191.6 KKK23443.1 - 0.00092 19.6 0.2 0.0059 17.0 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 KKK23443.1 - 0.0033 17.9 0.0 0.011 16.2 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) UvrD_C_2 PF13538.6 KKK23443.1 - 0.0035 17.1 1.1 0.022 14.6 0.5 2.3 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_22 PF13401.6 KKK23443.1 - 0.013 15.8 0.4 0.14 12.5 0.1 2.7 1 1 1 2 2 2 0 AAA domain DUF2075 PF09848.9 KKK23443.1 - 0.013 14.7 1.0 0.024 13.9 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) UvrD-helicase PF00580.21 KKK23443.1 - 0.034 13.7 0.0 0.11 12.0 0.0 1.8 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain DEAD PF00270.29 KKK23443.1 - 0.039 13.7 0.0 0.14 11.9 0.0 1.9 2 0 0 2 2 2 0 DEAD/DEAH box helicase Adeno_IVa2 PF02456.15 KKK23443.1 - 0.066 12.0 0.1 0.18 10.6 0.0 1.7 2 0 0 2 2 2 0 Adenovirus IVa2 protein AAA_5 PF07728.14 KKK23443.1 - 0.11 12.5 0.0 0.28 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ATPase_2 PF01637.18 KKK23443.1 - 0.11 12.4 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_25 PF13481.6 KKK23443.1 - 0.19 11.3 0.0 0.47 10.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 KKK23443.1 - 0.2 10.7 0.0 0.35 9.9 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 efThoc1 PF11957.8 KKK23444.1 - 2.1e-151 505.0 5.7 2.8e-151 504.5 5.7 1.1 1 0 0 1 1 1 1 THO complex subunit 1 transcription elongation factor Zf_RING PF16744.5 KKK23473.1 - 1.3e-05 25.2 0.3 3e-05 24.0 0.3 1.5 1 0 0 1 1 1 1 KIAA1045 RING finger Zn_ribbon_17 PF17120.5 KKK23473.1 - 5.2e-05 22.8 2.4 8.7e-05 22.1 2.4 1.3 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_2 PF13639.6 KKK23473.1 - 0.00059 20.1 3.4 0.00096 19.4 3.4 1.3 1 0 0 1 1 1 1 Ring finger domain C1_1 PF00130.22 KKK23473.1 - 0.0027 17.6 1.1 0.0046 16.8 1.1 1.3 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_4 PF16866.5 KKK23473.1 - 0.0032 17.5 0.6 0.26 11.4 0.0 2.4 1 1 1 2 2 2 1 PHD-finger Prok-RING_1 PF14446.6 KKK23473.1 - 0.0033 17.3 0.6 0.0062 16.4 0.6 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 FYVE PF01363.21 KKK23473.1 - 0.0096 16.0 0.2 0.018 15.2 0.2 1.4 1 0 0 1 1 1 1 FYVE zinc finger FXMRP1_C_core PF12235.8 KKK23473.1 - 0.04 14.5 3.3 0.11 13.1 3.3 1.7 1 0 0 1 1 1 0 Fragile X-related 1 protein core C terminal C1_2 PF03107.16 KKK23473.1 - 0.091 13.1 1.0 0.16 12.3 1.0 1.3 1 0 0 1 1 1 0 C1 domain PHD PF00628.29 KKK23473.1 - 0.096 12.6 1.2 0.18 11.7 1.2 1.4 1 0 0 1 1 1 0 PHD-finger zf-C3HC4_2 PF13923.6 KKK23473.1 - 0.19 11.6 1.2 0.34 10.8 1.2 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KKK23473.1 - 0.79 9.5 2.5 1.6 8.5 2.5 1.6 1 0 0 1 1 1 0 RING-like zinc finger zf-rbx1 PF12678.7 KKK23473.1 - 4.5 7.6 6.1 11 6.4 6.1 1.6 1 1 0 1 1 1 0 RING-H2 zinc finger domain R3H PF01424.22 KKK23474.1 - 8.9e-12 44.8 0.1 1.7e-11 43.9 0.1 1.5 1 0 0 1 1 1 1 R3H domain SDA1 PF05285.12 KKK23474.1 - 8.6e-05 22.1 5.2 0.00013 21.5 5.2 1.1 1 0 0 1 1 1 1 SDA1 SAPS PF04499.15 KKK23474.1 - 1.2 7.9 4.7 1.7 7.4 4.7 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Presenilin PF01080.17 KKK23474.1 - 3.4 6.4 5.1 4.9 5.8 5.1 1.2 1 0 0 1 1 1 0 Presenilin Trypan_PARP PF05887.11 KKK23474.1 - 6.9 6.7 14.3 0.99 9.4 8.8 2.3 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) ATP11 PF06644.11 KKK23475.1 - 2.9e-99 332.3 0.0 3.4e-99 332.0 0.0 1.0 1 0 0 1 1 1 1 ATP11 protein CAP_N PF01213.19 KKK23475.1 - 0.067 12.7 8.2 0.1 12.1 8.2 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Myb_DNA-bind_6 PF13921.6 KKK23475.1 - 0.078 13.2 0.1 0.15 12.3 0.1 1.4 1 0 0 1 1 1 0 Myb-like DNA-binding domain Evr1_Alr PF04777.13 KKK23476.1 - 1.5e-25 89.6 0.8 3.7e-25 88.3 0.0 2.1 2 0 0 2 2 2 1 Erv1 / Alr family zf-LYAR PF08790.11 KKK23476.1 - 2.2e-14 53.0 3.3 6.3e-14 51.6 3.3 1.9 1 0 0 1 1 1 1 LYAR-type C2HC zinc finger APOBEC4 PF18775.1 KKK23476.1 - 0.13 12.4 0.1 0.28 11.4 0.1 1.4 1 0 0 1 1 1 0 APOBEC4 MFS_1 PF07690.16 KKK23477.1 - 2.3e-17 63.0 56.3 1.6e-16 60.2 51.1 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF2976 PF11190.8 KKK23477.1 - 0.0011 18.7 0.3 0.0011 18.7 0.3 4.3 5 0 0 5 5 5 1 Protein of unknown function (DUF2976) MFS_1 PF07690.16 KKK23478.1 - 2e-20 73.0 34.5 1.1e-19 70.7 31.8 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily HAD PF12710.7 KKK23479.1 - 4.8e-24 85.8 0.0 6.8e-24 85.3 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 KKK23479.1 - 5.4e-06 26.0 0.0 0.042 13.3 0.0 2.0 2 0 0 2 2 2 2 Putative Phosphatase Hydrolase PF00702.26 KKK23479.1 - 0.032 14.5 0.6 0.13 12.6 0.1 2.2 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase UMPH-1 PF05822.12 KKK23479.1 - 0.16 11.4 0.1 0.63 9.5 0.0 2.0 3 1 1 4 4 4 0 Pyrimidine 5'-nucleotidase (UMPH-1) MFS_1 PF07690.16 KKK23480.1 - 5.3e-25 88.1 26.4 4e-13 49.0 12.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KKK23480.1 - 0.00013 21.0 8.6 0.0027 16.7 0.4 2.1 1 1 0 2 2 2 2 MFS_1 like family Sugar_tr PF00083.24 KKK23480.1 - 0.011 14.6 13.4 0.087 11.7 13.4 2.0 1 1 0 1 1 1 0 Sugar (and other) transporter AA_permease_2 PF13520.6 KKK23482.1 - 8.1e-69 232.5 40.0 1.1e-68 232.0 40.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KKK23482.1 - 4.2e-23 81.7 33.5 5.7e-23 81.3 33.5 1.1 1 0 0 1 1 1 1 Amino acid permease p450 PF00067.22 KKK23483.1 - 1.8e-66 224.8 0.0 2.4e-66 224.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Sigma70_ECF PF07638.11 KKK23484.1 - 0.053 13.4 3.1 0.12 12.3 3.1 1.5 1 0 0 1 1 1 0 ECF sigma factor D-ser_dehydrat PF14031.6 KKK23485.1 - 6.8e-21 74.7 0.0 1.8e-20 73.4 0.0 1.8 1 0 0 1 1 1 1 Putative serine dehydratase domain Ala_racemase_N PF01168.20 KKK23485.1 - 5.8e-12 45.7 0.1 1e-11 44.9 0.1 1.4 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain TauD PF02668.16 KKK23486.1 - 1.4e-27 97.2 0.1 2.3e-27 96.5 0.1 1.3 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family LssY_C PF14067.6 KKK23486.1 - 0.14 11.7 0.0 0.98 8.9 0.0 2.2 2 0 0 2 2 2 0 LssY C-terminus Mucin PF01456.17 KKK23486.1 - 2.6 8.0 16.5 4 7.4 16.5 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Dicty_REP PF05086.12 KKK23486.1 - 3.2 5.6 3.2 4.4 5.1 3.2 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein adh_short PF00106.25 KKK23488.1 - 4e-42 143.9 0.0 5.5e-42 143.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KKK23488.1 - 2.7e-27 95.9 0.5 4.9e-27 95.0 0.5 1.4 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KKK23488.1 - 8.4e-07 29.1 0.3 1.3e-06 28.4 0.3 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 KKK23488.1 - 0.00037 20.0 0.0 0.00046 19.6 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 KKK23488.1 - 0.014 14.8 0.4 0.025 14.1 0.4 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KKK23488.1 - 0.033 13.3 0.1 0.055 12.6 0.1 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain ADH_zinc_N PF00107.26 KKK23488.1 - 0.11 12.5 0.3 0.21 11.6 0.3 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Zn_clus PF00172.18 KKK23489.1 - 1.8e-10 40.8 19.2 6.1e-06 26.3 11.0 2.6 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KKK23489.1 - 3e-08 33.0 0.0 8.5e-08 31.5 0.0 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain K_trans PF02705.16 KKK23490.1 - 2.2e-179 597.4 19.0 2.6e-179 597.2 19.0 1.0 1 0 0 1 1 1 1 K+ potassium transporter DUF4064 PF13273.6 KKK23490.1 - 0.019 15.3 5.9 0.019 15.3 5.9 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF4064) PaaX PF07848.12 KKK23491.1 - 0.087 13.1 0.1 1.8 8.9 0.0 2.2 1 1 1 2 2 2 0 PaaX-like protein GntR PF00392.21 KKK23491.1 - 0.097 12.3 0.3 0.61 9.8 0.0 2.0 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family eIF2A PF08662.11 KKK23492.1 - 8.2e-38 130.2 3.8 8.2e-36 123.7 0.8 4.0 3 2 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.22 KKK23492.1 - 2e-07 30.7 0.0 5.3e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.32 KKK23492.1 - 0.0075 17.1 0.9 1.1 10.2 0.1 4.0 3 0 0 3 3 3 1 WD domain, G-beta repeat zf-C3HC4_3 PF13920.6 KKK23493.1 - 3e-07 30.2 9.1 3e-07 30.2 9.1 3.3 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KKK23493.1 - 8.1 6.4 22.9 0.032 14.1 11.2 2.6 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) SWIB PF02201.18 KKK23494.1 - 9e-29 99.2 0.1 1.8e-28 98.2 0.1 1.5 1 0 0 1 1 1 1 SWIB/MDM2 domain DEK_C PF08766.11 KKK23494.1 - 1e-16 60.5 0.1 2e-16 59.6 0.1 1.5 1 0 0 1 1 1 1 DEK C terminal domain Ndc1_Nup PF09531.10 KKK23494.1 - 8.5 4.9 6.5 9.5 4.8 6.5 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup WD40 PF00400.32 KKK23495.1 - 2.4e-59 195.9 29.7 1.9e-11 44.3 0.1 9.1 8 1 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKK23495.1 - 1.5e-18 66.9 3.6 0.00036 20.8 0.1 5.9 3 2 3 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KKK23495.1 - 1.2e-08 35.1 0.1 0.02 14.8 0.0 3.5 2 2 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KKK23495.1 - 1.1e-06 27.6 5.9 0.19 10.4 0.1 5.7 4 2 2 6 6 6 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KKK23495.1 - 1.1e-05 24.6 1.4 2.7 6.9 0.0 5.0 3 3 2 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein NLE PF08154.12 KKK23495.1 - 1.3e-05 25.6 0.0 2.9e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 NLE (NUC135) domain FAD_binding_9 PF08021.11 KKK23495.1 - 0.0046 17.2 0.0 0.43 10.8 0.0 2.6 2 0 0 2 2 2 1 Siderophore-interacting FAD-binding domain 120_Rick_ant PF12574.8 KKK23495.1 - 0.006 15.8 0.5 0.1 11.8 0.0 2.2 2 0 0 2 2 2 1 120 KDa Rickettsia surface antigen WD40_like PF17005.5 KKK23495.1 - 0.009 15.4 0.0 21 4.3 0.0 4.0 4 1 1 5 5 5 0 WD40-like domain DUF4550 PF15084.6 KKK23495.1 - 0.013 15.9 0.0 0.074 13.5 0.0 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4550) MutS_V PF00488.21 KKK23496.1 - 9.7e-62 208.3 0.7 2.2e-61 207.2 0.7 1.6 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KKK23496.1 - 5.8e-32 111.5 3.3 5.8e-32 111.5 3.3 2.2 3 0 0 3 3 3 1 MutS domain III MutS_IV PF05190.18 KKK23496.1 - 7.6e-13 48.6 0.4 2.1e-12 47.2 0.2 2.0 2 0 0 2 2 2 1 MutS family domain IV MutS_II PF05188.17 KKK23496.1 - 1e-10 42.0 0.3 2.9e-10 40.5 0.3 1.8 1 0 0 1 1 1 1 MutS domain II AAA_30 PF13604.6 KKK23496.1 - 0.0012 18.5 0.3 0.009 15.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain DDE_Tnp_1 PF01609.21 KKK23496.1 - 0.045 13.4 0.0 0.096 12.3 0.0 1.5 1 0 0 1 1 1 0 Transposase DDE domain AAA_27 PF13514.6 KKK23496.1 - 0.052 13.1 0.2 1.4 8.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain Response_reg PF00072.24 KKK23497.1 - 2.1e-21 76.2 0.3 5.3e-21 74.9 0.1 1.8 2 0 0 2 2 2 1 Response regulator receiver domain HATPase_c PF02518.26 KKK23497.1 - 5.9e-19 68.6 0.1 1.3e-18 67.5 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 KKK23497.1 - 4.7e-12 45.7 0.3 1.3e-11 44.3 0.3 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain ABC2_membrane PF01061.24 KKK23498.1 - 4.5e-82 274.5 50.5 2.5e-46 157.7 19.4 2.6 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 KKK23498.1 - 2.8e-40 138.0 0.0 4.8e-19 69.2 0.0 2.8 3 0 0 3 3 2 2 ABC transporter PDR_CDR PF06422.12 KKK23498.1 - 1.8e-21 75.9 0.1 1.8e-21 75.9 0.1 4.2 5 0 0 5 5 5 2 CDR ABC transporter ABC2_membrane_3 PF12698.7 KKK23498.1 - 8.6e-11 41.5 29.2 7.8e-09 35.1 11.9 2.7 3 1 0 3 3 3 2 ABC-2 family transporter protein AAA_16 PF13191.6 KKK23498.1 - 5.8e-06 26.8 0.0 0.0021 18.4 0.1 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 KKK23498.1 - 0.00011 22.7 0.0 0.0065 17.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 KKK23498.1 - 0.00036 20.4 0.0 0.11 12.3 0.0 2.9 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 KKK23498.1 - 0.0013 19.0 0.0 0.039 14.2 0.0 3.0 3 1 0 3 3 3 1 AAA domain RsgA_GTPase PF03193.16 KKK23498.1 - 0.0014 18.5 0.0 0.0089 15.9 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 KKK23498.1 - 0.0051 16.5 0.0 0.12 12.2 0.0 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain SMC_N PF02463.19 KKK23498.1 - 0.008 15.6 0.0 5.1 6.5 0.0 3.0 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 KKK23498.1 - 0.021 14.9 0.0 6.6 6.9 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_28 PF13521.6 KKK23498.1 - 0.021 15.0 0.1 0.079 13.2 0.1 2.0 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KKK23498.1 - 0.023 14.9 0.0 0.23 11.6 0.0 2.6 3 0 0 3 3 3 0 AAA domain DnaB_C PF03796.15 KKK23498.1 - 0.062 12.6 0.0 5.2 6.3 0.0 2.2 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain NACHT PF05729.12 KKK23498.1 - 0.092 12.7 0.3 2.9 7.8 0.1 2.9 3 0 0 3 3 3 0 NACHT domain AAA_30 PF13604.6 KKK23498.1 - 0.15 11.8 0.0 2.1 8.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain SSFA2_C PF14723.6 KKK23499.1 - 0.086 12.7 0.0 0.086 12.7 0.0 2.2 2 0 0 2 2 2 0 Sperm-specific antigen 2 C-terminus Sugar_tr PF00083.24 KKK23500.1 - 4.5e-78 263.1 14.2 5.5e-78 262.8 14.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKK23500.1 - 4.1e-17 62.2 24.1 4.1e-17 62.2 24.1 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily SK_channel PF03530.14 KKK23500.1 - 0.084 12.9 0.0 0.32 11.0 0.0 2.0 2 0 0 2 2 2 0 Calcium-activated SK potassium channel Zn_clus PF00172.18 KKK23501.1 - 1.5e-08 34.6 13.3 3e-08 33.7 13.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KKK23501.1 - 3.4e-08 32.8 0.4 2.4e-07 30.1 0.0 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain PFK PF00365.20 KKK23502.1 - 9.3e-193 638.8 0.5 4e-105 351.2 0.0 2.1 2 0 0 2 2 2 2 Phosphofructokinase DAGK_cat PF00781.24 KKK23502.1 - 0.009 15.6 0.0 0.14 11.8 0.1 2.6 2 0 0 2 2 2 1 Diacylglycerol kinase catalytic domain DUF4646 PF15496.6 KKK23503.1 - 2.2e-09 38.0 0.0 2.2e-08 34.8 0.0 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF4646) DUF2062 PF09835.9 KKK23503.1 - 0.13 12.1 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) ISN1 PF06437.11 KKK23504.1 - 1.2e-199 663.4 0.0 1.3e-199 663.2 0.0 1.0 1 0 0 1 1 1 1 IMP-specific 5'-nucleotidase PAC3 PF10178.9 KKK23505.1 - 3.6e-06 27.0 0.0 5.4e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Proteasome assembly chaperone 3 Tyr-DNA_phospho PF06087.12 KKK23506.1 - 1.1e-85 288.1 0.0 2.1e-66 224.6 0.0 2.2 1 1 1 2 2 2 2 Tyrosyl-DNA phosphodiesterase UIM PF02809.20 KKK23506.1 - 3.7e-06 26.5 8.5 0.00092 19.0 1.3 2.6 2 0 0 2 2 2 2 Ubiquitin interaction motif RAP80_UIM PF18282.1 KKK23506.1 - 0.012 15.4 1.6 4.6 7.1 0.1 2.8 3 0 0 3 3 3 0 RAP80 N-terminal ubiquitin interaction motif PDR_CDR PF06422.12 KKK23507.1 - 0.017 15.0 1.8 0.031 14.2 1.8 1.5 1 0 0 1 1 1 0 CDR ABC transporter PUF PF00806.19 KKK23508.1 - 3.5e-66 215.3 14.4 1e-09 37.5 0.0 8.5 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat CPL PF08144.11 KKK23508.1 - 0.00044 20.6 2.3 6.6 7.1 0.0 4.8 2 1 2 4 4 4 2 CPL (NUC119) domain sCache_2 PF17200.4 KKK23508.1 - 0.0016 18.3 1.2 20 5.0 0.0 4.8 4 1 1 5 5 5 1 Single Cache domain 2 Dscam_C PF12355.8 KKK23508.1 - 0.028 15.4 9.3 0.028 15.4 9.3 2.3 2 0 0 2 2 2 0 Down syndrome cell adhesion molecule C terminal DUF234 PF03008.14 KKK23508.1 - 1.1 9.8 2.8 1.8 9.0 0.3 2.5 3 0 0 3 3 3 0 Archaea bacterial proteins of unknown function cwf21 PF08312.12 KKK23509.1 - 9.3e-20 70.5 10.8 9.3e-20 70.5 10.8 2.5 2 1 0 2 2 2 1 cwf21 domain Tho2 PF11262.8 KKK23509.1 - 2.3 7.3 3.5 3.4 6.8 3.5 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 HA2 PF04408.23 KKK23510.1 - 6.9e-27 93.9 0.0 6.9e-27 93.9 0.0 3.1 3 0 0 3 3 3 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KKK23510.1 - 2.8e-12 47.0 0.0 1.5e-11 44.6 0.0 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.29 KKK23510.1 - 1e-08 35.2 0.0 3e-08 33.6 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.16 KKK23510.1 - 1.6e-07 31.5 0.0 4.1e-07 30.3 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_22 PF13401.6 KKK23510.1 - 8.2e-05 22.9 0.9 0.00092 19.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 KKK23510.1 - 0.00019 21.5 1.0 0.5 10.4 0.0 3.1 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit T2SSE PF00437.20 KKK23510.1 - 0.007 15.5 0.0 0.016 14.3 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.6 KKK23510.1 - 0.033 14.5 0.0 0.073 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 KKK23510.1 - 0.075 12.4 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family SWI2_SNF2 PF18766.1 KKK23510.1 - 0.2 11.3 2.9 8.2 6.0 0.5 3.0 2 1 0 2 2 2 0 SWI2/SNF2 ATPase F-box PF00646.33 KKK23511.1 - 0.0041 16.9 0.4 14 5.7 0.0 3.6 3 0 0 3 3 3 1 F-box domain F-box-like PF12937.7 KKK23511.1 - 0.0052 16.7 10.0 0.1 12.5 6.6 3.5 3 1 0 3 3 3 1 F-box-like Adeno_PV PF03910.13 KKK23511.1 - 0.0079 15.0 0.4 0.013 14.3 0.4 1.2 1 0 0 1 1 1 1 Adenovirus minor core protein PV Cytokin_check_N PF10407.9 KKK23511.1 - 0.046 13.7 0.4 0.16 12.0 0.0 2.0 2 0 0 2 2 2 0 Cdc14 phosphatase binding protein N-terminus Glyco_transf_11 PF01531.16 KKK23511.1 - 0.19 10.9 0.0 0.33 10.1 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 11 Glyco_hydro_3_C PF01915.22 KKK23512.1 - 2.4e-48 164.8 0.0 4.9e-48 163.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KKK23512.1 - 2.5e-40 138.8 0.0 4.2e-40 138.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KKK23512.1 - 5.8e-21 74.4 0.1 1.7e-20 72.9 0.0 1.9 2 0 0 2 2 2 1 Fibronectin type III-like domain bZIP_1 PF00170.21 KKK23512.1 - 2.4e-06 27.5 9.8 4.4e-06 26.7 9.8 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KKK23512.1 - 0.0039 17.3 12.0 0.0066 16.5 12.0 1.4 1 0 0 1 1 1 1 Basic region leucine zipper HALZ PF02183.18 KKK23512.1 - 0.01 16.1 0.4 0.021 15.1 0.4 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper Mitofilin PF09731.9 KKK23512.1 - 0.03 13.2 3.2 0.043 12.7 3.2 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein JIP_LZII PF16471.5 KKK23512.1 - 0.1 12.7 1.0 0.23 11.6 1.0 1.5 1 0 0 1 1 1 0 JNK-interacting protein leucine zipper II bZIP_Maf PF03131.17 KKK23512.1 - 0.15 12.6 7.4 0.27 11.8 7.4 1.3 1 0 0 1 1 1 0 bZIP Maf transcription factor Tmemb_cc2 PF10267.9 KKK23512.1 - 0.19 10.8 4.8 0.28 10.3 4.8 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Romo1 PF10247.9 KKK23513.1 - 0.055 13.9 0.3 1.6 9.1 0.1 2.3 2 0 0 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 ThrE PF06738.12 KKK23514.1 - 2.6e-70 236.5 12.7 2.8e-65 220.0 2.7 2.3 2 0 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 KKK23514.1 - 1.7e-13 50.9 7.1 1.7e-13 50.9 7.1 2.5 2 0 0 2 2 2 1 Threonine/Serine exporter, ThrE DLH PF01738.18 KKK23517.1 - 4e-06 26.6 0.0 2.1e-05 24.2 0.0 1.9 1 1 0 1 1 1 1 Dienelactone hydrolase family AXE1 PF05448.12 KKK23517.1 - 0.00028 19.7 0.2 0.00093 18.0 0.2 1.7 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) BAAT_C PF08840.11 KKK23517.1 - 0.0011 19.0 0.0 0.0016 18.4 0.0 1.3 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S9 PF00326.21 KKK23517.1 - 0.016 14.7 0.0 0.34 10.4 0.0 2.3 2 0 0 2 2 2 0 Prolyl oligopeptidase family Esterase_phd PF10503.9 KKK23517.1 - 0.027 14.0 0.3 0.035 13.6 0.3 1.2 1 0 0 1 1 1 0 Esterase PHB depolymerase Hydrolase_4 PF12146.8 KKK23517.1 - 0.056 12.7 0.0 0.094 12.0 0.0 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Acyl_transf_2 PF02273.15 KKK23517.1 - 0.22 10.7 0.0 0.31 10.2 0.0 1.2 1 0 0 1 1 1 0 Acyl transferase Transketolase_N PF00456.21 KKK23518.1 - 5.1e-13 48.7 0.7 9.9e-12 44.4 0.7 2.1 1 1 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transketolase_C PF02780.20 KKK23518.1 - 3e-09 36.8 0.0 1.2e-08 34.8 0.0 2.0 2 0 0 2 2 2 1 Transketolase, C-terminal domain Transket_pyr PF02779.24 KKK23518.1 - 2e-05 24.3 1.2 0.00015 21.5 0.2 2.3 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain TPP_enzyme_C PF02775.21 KKK23518.1 - 0.0055 16.5 0.7 0.026 14.3 0.7 2.0 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain STG PF15809.5 KKK23518.1 - 0.093 12.8 0.0 0.14 12.2 0.0 1.2 1 0 0 1 1 1 0 Simian taste bud-specific gene product family E1_dh PF00676.20 KKK23518.1 - 0.1 11.5 0.0 0.18 10.7 0.0 1.4 1 0 0 1 1 1 0 Dehydrogenase E1 component nlz1 PF12402.8 KKK23518.1 - 0.19 12.2 1.3 21 5.7 0.0 2.8 3 0 0 3 3 3 0 NocA-like zinc-finger protein 1 PORR PF11955.8 KKK23519.1 - 0.13 11.1 0.1 0.19 10.7 0.1 1.1 1 0 0 1 1 1 0 Plant organelle RNA recognition domain Histone PF00125.24 KKK23520.1 - 1e-51 174.7 2.5 1.1e-51 174.6 2.5 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 KKK23520.1 - 6e-06 26.6 0.0 9e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 KKK23520.1 - 4.9e-05 23.4 0.5 7.4e-05 22.8 0.1 1.5 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 KKK23520.1 - 6.5e-05 23.5 1.2 7.7e-05 23.3 1.2 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CBFD_NFYB_HMF PF00808.23 KKK23520.1 - 0.0032 17.7 0.3 0.0065 16.7 0.0 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 KKK23520.1 - 0.026 14.6 0.2 0.042 13.9 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit CENP-T_C PF15511.6 KKK23521.1 - 2.9e-08 33.8 0.0 4e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 KKK23521.1 - 4.9e-05 23.7 0.1 6.3e-05 23.3 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.17 KKK23521.1 - 0.00015 21.9 0.1 0.00022 21.3 0.1 1.4 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 KKK23521.1 - 0.00044 20.5 0.1 0.00075 19.7 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 KKK23521.1 - 0.00087 19.6 0.1 0.0013 19.1 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 KKK23521.1 - 0.018 15.1 0.0 0.024 14.7 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 KKK23521.1 - 0.06 13.4 0.0 0.085 12.9 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated UPF0137 PF03677.13 KKK23521.1 - 0.17 11.7 0.2 0.22 11.3 0.2 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) MFS_1 PF07690.16 KKK23522.1 - 1.2e-39 136.2 56.1 1.2e-39 136.2 56.1 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily TPR_19 PF14559.6 KKK23523.1 - 5.5e-06 26.8 2.0 0.11 13.0 0.0 2.8 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 KKK23523.1 - 1.7e-05 25.4 0.8 0.0013 19.3 0.2 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 KKK23523.1 - 0.0012 19.5 2.7 0.3 12.0 0.2 3.0 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 KKK23523.1 - 0.0018 18.5 0.1 1.1 9.8 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KKK23523.1 - 0.048 13.9 0.3 0.32 11.3 0.1 2.2 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 KKK23523.1 - 0.056 13.7 0.4 0.77 10.1 0.1 2.6 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 KKK23523.1 - 0.11 12.7 1.0 66 4.0 0.0 4.0 5 0 0 5 5 5 0 Tetratricopeptide repeat UQ_con PF00179.26 KKK23524.1 - 4.6e-16 58.7 0.0 5e-16 58.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Staph_opine_DH PF10100.9 KKK23525.1 - 0.0045 15.7 0.0 0.0055 15.4 0.0 1.0 1 0 0 1 1 1 1 Staphylopine dehydrogenase SKI PF01202.22 KKK23525.1 - 0.005 17.0 0.0 0.0062 16.7 0.0 1.1 1 0 0 1 1 1 1 Shikimate kinase AAA_33 PF13671.6 KKK23525.1 - 0.0078 16.4 0.0 0.0095 16.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KKK23525.1 - 0.047 14.2 0.0 0.093 13.3 0.0 1.5 1 1 0 1 1 1 0 AAA domain Sec7_N PF12783.7 KKK23526.1 - 6.5e-44 149.6 0.5 6.5e-44 149.6 0.5 4.4 4 1 0 4 4 4 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DCB PF16213.5 KKK23526.1 - 7.4e-41 139.8 4.6 3e-40 137.8 4.6 2.2 1 0 0 1 1 1 1 Dimerisation and cyclophilin-binding domain of Mon2 Mon2_C PF16206.5 KKK23526.1 - 6.9e-22 77.4 2.1 1.3e-21 76.5 1.3 1.8 2 0 0 2 2 2 1 C-terminal region of Mon2 protein DUF1981 PF09324.10 KKK23526.1 - 0.1 12.5 0.1 21 5.0 0.0 4.2 3 0 0 3 3 3 0 Domain of unknown function (DUF1981) NAD_binding_1 PF00175.21 KKK23542.1 - 2.5e-34 118.2 0.0 4e-34 117.6 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KKK23542.1 - 9.2e-22 77.3 0.0 1.9e-21 76.3 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 KKK23542.1 - 3e-08 33.9 0.0 0.00047 20.3 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain B12D PF06522.11 KKK23542.1 - 0.069 12.9 0.0 8.9 6.2 0.0 2.4 2 0 0 2 2 2 0 NADH-ubiquinone reductase complex 1 MLRQ subunit Ribosomal_L18A PF01775.17 KKK23543.1 - 5.1e-55 184.7 0.2 6.4e-55 184.4 0.2 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A zf-Tim10_DDP PF02953.15 KKK23544.1 - 2.9e-23 81.3 0.8 3.5e-23 81.0 0.8 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger CLTH PF10607.9 KKK23545.1 - 4.8e-34 117.4 0.4 2.8e-33 114.9 0.0 2.3 2 1 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.6 KKK23545.1 - 3.7e-07 30.1 1.7 8.4e-07 28.9 1.7 1.7 1 0 0 1 1 1 1 RING-type zinc-finger Rtf2 PF04641.12 KKK23545.1 - 0.00019 20.9 0.3 0.00019 20.9 0.3 2.4 3 0 0 3 3 3 1 Rtf2 RING-finger zf-RING_5 PF14634.6 KKK23545.1 - 0.0013 18.7 2.0 0.0025 17.8 2.0 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 KKK23545.1 - 0.0014 18.9 2.7 0.0027 18.0 2.7 1.5 1 0 0 1 1 1 1 Ring finger domain INTS5_N PF14837.6 KKK23545.1 - 0.015 14.9 0.5 1.3 8.6 0.0 3.0 2 1 1 3 3 3 0 Integrator complex subunit 5 N-terminus FAP206 PF12018.8 KKK23545.1 - 0.025 14.1 0.5 0.052 13.0 0.5 1.5 1 0 0 1 1 1 0 Domain of unknown function Prok-RING_4 PF14447.6 KKK23545.1 - 0.031 14.1 2.9 0.066 13.1 2.9 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 KKK23545.1 - 0.065 13.1 3.8 0.16 11.8 3.8 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF4047 PF13256.6 KKK23545.1 - 0.097 12.9 0.2 0.19 11.9 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4047) zf-C3HC4_3 PF13920.6 KKK23545.1 - 0.1 12.5 2.4 0.19 11.6 2.4 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) V_ATPase_I PF01496.19 KKK23545.1 - 0.16 9.8 2.8 0.2 9.6 2.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family zf-C3HC4 PF00097.25 KKK23545.1 - 0.17 11.8 4.0 0.34 10.8 4.0 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KKK23545.1 - 0.29 11.3 3.0 0.63 10.3 3.0 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING PIN_8 PF18476.1 KKK23545.1 - 5.7 6.7 7.8 0.87 9.4 1.9 2.1 1 1 0 2 2 2 0 PIN like domain FlaC_arch PF05377.11 KKK23546.1 - 0.072 13.5 1.1 0.29 11.6 0.1 2.3 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) PG_binding_1 PF01471.18 KKK23546.1 - 0.14 12.4 0.0 7.7 6.8 0.0 3.2 3 0 0 3 3 3 0 Putative peptidoglycan binding domain DUF2730 PF10805.8 KKK23546.1 - 0.15 12.2 0.2 0.41 10.8 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) HrpB7 PF09486.10 KKK23546.1 - 0.23 11.9 0.1 0.23 11.9 0.1 2.0 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) HMMR_N PF15905.5 KKK23546.1 - 0.44 10.0 3.9 2.3 7.6 0.1 2.5 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal PCI PF01399.27 KKK23547.1 - 1.5e-09 38.3 0.0 3.3e-09 37.2 0.0 1.6 1 0 0 1 1 1 1 PCI domain DUF433 PF04255.14 KKK23547.1 - 0.024 14.5 0.0 0.057 13.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF433) ARID PF01388.21 KKK23547.1 - 0.15 12.7 0.0 0.74 10.5 0.0 2.1 2 0 0 2 2 2 0 ARID/BRIGHT DNA binding domain BTB PF00651.31 KKK23548.1 - 2.2e-05 24.6 0.1 0.0002 21.6 0.0 2.4 3 0 0 3 3 3 1 BTB/POZ domain C_Hendra PF16821.5 KKK23555.1 - 0.0023 17.8 3.3 0.0023 17.8 3.3 3.3 2 1 0 3 3 3 1 C protein from hendra and measles viruses SOG2 PF10428.9 KKK23555.1 - 9.7 5.3 19.8 14 4.8 19.8 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein S1 PF00575.23 KKK23556.1 - 1.3e-65 217.7 25.2 2.2e-12 47.2 0.9 11.7 11 0 0 11 11 11 10 S1 RNA binding domain TPR_14 PF13428.6 KKK23556.1 - 5.2e-07 29.9 0.4 0.8 10.7 0.1 5.4 3 2 2 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 KKK23556.1 - 1.3e-06 28.8 0.1 0.033 14.7 0.1 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat Suf PF05843.14 KKK23556.1 - 1.7e-05 25.0 0.8 0.14 12.2 0.1 3.5 1 1 1 2 2 2 2 Suppressor of forked protein (Suf) RNase_II_C_S1 PF18614.1 KKK23556.1 - 1.8e-05 24.6 6.9 1.3 9.0 0.0 6.4 7 0 0 7 7 7 3 RNase II-type exonuclease C-terminal S1 domain PPR PF01535.20 KKK23556.1 - 0.0058 16.8 0.1 2 8.9 0.0 3.5 3 0 0 3 3 3 1 PPR repeat TPR_16 PF13432.6 KKK23556.1 - 0.018 15.6 0.1 60 4.4 0.0 3.7 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 KKK23556.1 - 0.021 15.0 0.5 2.5 8.5 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat NRDE-2 PF08424.10 KKK23556.1 - 0.024 13.8 0.0 0.76 8.8 0.1 2.5 2 0 0 2 2 2 0 NRDE-2, necessary for RNA interference TPR_7 PF13176.6 KKK23556.1 - 0.071 13.2 0.5 2.3 8.4 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 KKK23556.1 - 0.11 12.7 1.7 7 7.0 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 KKK23556.1 - 0.11 13.2 1.1 1.1e+02 3.7 0.1 4.4 4 0 0 4 4 3 0 Tetratricopeptide repeat S1_2 PF13509.6 KKK23556.1 - 0.13 12.3 0.1 3.6 7.7 0.0 3.4 3 0 0 3 3 2 0 S1 domain TPR_15 PF13429.6 KKK23556.1 - 0.16 11.1 0.3 0.81 8.8 0.3 2.0 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_12 PF13424.6 KKK23556.1 - 0.29 11.5 0.5 23 5.3 0.0 3.4 2 1 1 3 3 3 0 Tetratricopeptide repeat UreD PF01774.17 KKK23557.1 - 4.1e-67 226.2 0.0 5.2e-67 225.9 0.0 1.1 1 0 0 1 1 1 1 UreD urease accessory protein DUF2729 PF10870.8 KKK23558.1 - 0.059 13.2 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2729) tRNA-synt_2b PF00587.25 KKK23559.1 - 6.9e-19 68.5 0.0 1.3e-18 67.6 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 KKK23559.1 - 1.3e-11 44.5 0.0 2.9e-11 43.4 0.0 1.7 1 0 0 1 1 1 1 Anticodon binding domain ProRS-C_1 PF09180.11 KKK23559.1 - 2.7e-09 37.1 0.0 6.4e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal WD40 PF00400.32 KKK23561.1 - 7.1e-14 52.0 0.4 0.013 16.3 0.0 5.6 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKK23561.1 - 6.1e-05 23.2 0.0 3.6 8.0 0.0 4.7 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KKK23561.1 - 0.091 12.1 0.0 0.16 11.2 0.0 1.4 1 0 0 1 1 1 0 WD40-like domain Cpn60_TCP1 PF00118.24 KKK23562.1 - 1.3e-150 502.3 17.2 1.5e-150 502.1 17.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family STAG PF08514.11 KKK23563.1 - 1.2e-35 121.9 2.0 1.2e-35 121.9 2.0 3.1 3 0 0 3 3 3 1 STAG domain YL1 PF05764.13 KKK23563.1 - 0.0055 16.9 11.4 0.0055 16.9 11.4 4.6 4 1 1 5 5 5 1 YL1 nuclear protein HEAT_2 PF13646.6 KKK23563.1 - 0.011 16.1 4.7 0.39 11.2 0.2 4.3 3 1 1 4 4 4 0 HEAT repeats HEAT PF02985.22 KKK23563.1 - 0.1 12.9 0.0 1e+02 3.6 0.0 4.5 6 0 0 6 6 6 0 HEAT repeat DUF5596 PF18082.1 KKK23563.1 - 0.11 12.3 0.7 0.43 10.4 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5596) BAG6 PF12057.8 KKK23563.1 - 0.15 11.8 0.1 0.47 10.1 0.1 1.8 1 0 0 1 1 1 0 BCL2-associated athanogene 6 FlgM PF04316.13 KKK23563.1 - 0.73 10.2 8.6 0.49 10.8 1.4 3.9 4 0 0 4 4 4 0 Anti-sigma-28 factor, FlgM Y_phosphatase3 PF13350.6 KKK23565.1 - 8.9e-54 182.9 0.0 1e-53 182.7 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 KKK23565.1 - 0.0025 17.4 0.0 0.0041 16.7 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 KKK23565.1 - 0.0081 15.8 0.0 0.012 15.2 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Myotub-related PF06602.14 KKK23565.1 - 0.083 11.8 0.0 0.12 11.3 0.0 1.1 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain PTPlike_phytase PF14566.6 KKK23565.1 - 0.12 12.5 0.0 0.23 11.6 0.0 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate Mucin PF01456.17 KKK23594.1 - 1.8 8.5 10.4 3.9 7.5 10.4 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein RabGAP-TBC PF00566.18 KKK23595.1 - 1.5e-42 145.7 0.5 2.8e-42 144.8 0.5 1.5 1 0 0 1 1 1 1 Rab-GTPase-TBC domain PH_RBD PF12068.8 KKK23595.1 - 2e-08 33.9 0.0 0.001 18.6 0.0 3.8 3 1 0 3 3 3 2 Rab-binding domain (RBD) Ring_hydroxyl_A PF00848.19 KKK23596.1 - 2e-21 76.9 2.6 1.2e-10 41.8 0.1 2.2 1 1 1 2 2 2 2 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.26 KKK23597.1 - 4.9e-15 55.2 0.0 9.4e-15 54.3 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Spore_coat_CotO PF14153.6 KKK23633.1 - 3.5 7.5 6.9 7.5 6.4 6.9 1.5 1 0 0 1 1 1 0 Spore coat protein CotO Vps35 PF03635.17 KKK23634.1 - 0 1012.1 0.3 0 1011.9 0.3 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 DUF3907 PF13047.6 KKK23634.1 - 0.085 12.8 0.1 7.9 6.4 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3907) Cyt-b5 PF00173.28 KKK23635.1 - 0.0036 17.4 0.0 0.0047 17.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Ish1 PF10281.9 KKK23636.1 - 8.5e-86 282.0 12.3 3.2e-12 46.6 0.1 7.4 7 0 0 7 7 7 7 Putative stress-responsive nuclear envelope protein SAP PF02037.27 KKK23636.1 - 1.2e-10 40.9 0.0 0.67 9.8 0.0 6.3 5 1 0 5 5 5 3 SAP domain HeH PF12949.7 KKK23636.1 - 2.2e-09 36.9 0.0 0.38 10.5 0.0 5.6 6 0 0 6 6 6 2 HeH/LEM domain ANAPC2 PF08672.11 KKK23636.1 - 9.4e-05 22.9 0.6 34 5.0 0.0 5.6 6 0 0 6 6 6 0 Anaphase promoting complex (APC) subunit 2 Slx4 PF09494.10 KKK23636.1 - 9.5e-05 22.3 3.5 20 5.3 0.0 5.8 7 0 0 7 7 7 0 Slx4 endonuclease LEM PF03020.15 KKK23636.1 - 0.027 14.0 0.0 18 5.0 0.0 4.0 5 0 0 5 5 5 0 LEM domain CPSase_sm_chain PF00988.22 KKK23636.1 - 0.088 12.6 0.0 10 6.0 0.0 3.7 5 0 0 5 5 5 0 Carbamoyl-phosphate synthase small chain, CPSase domain SAM_2 PF07647.17 KKK23636.1 - 0.22 11.7 9.3 15 5.8 0.0 5.9 6 1 1 7 7 7 0 SAM domain (Sterile alpha motif) TIR_2 PF13676.6 KKK23636.1 - 0.32 11.6 2.3 1.2 9.8 0.2 3.0 2 1 1 3 3 2 0 TIR domain DUF4230 PF14014.6 KKK23636.1 - 2.5 8.4 4.2 42 4.4 0.8 3.5 3 1 1 4 4 4 0 Protein of unknown function (DUF4230) Apolipoprotein PF01442.18 KKK23636.1 - 3.9 7.3 12.6 5.1 6.9 7.4 3.1 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain PQ-loop PF04193.14 KKK23637.1 - 4.7e-20 71.1 15.0 2.8e-11 43.0 5.2 3.5 3 1 1 4 4 4 2 PQ loop repeat LtrA PF06772.11 KKK23637.1 - 0.019 14.2 4.4 0.045 13.0 4.6 1.6 1 1 0 1 1 1 0 Bacterial low temperature requirement A protein (LtrA) CTV_P6 PF06706.11 KKK23637.1 - 0.18 11.5 2.9 0.9 9.3 0.5 2.6 2 0 0 2 2 2 0 Citrus tristeza virus 6-kDa protein YwiC PF14256.6 KKK23637.1 - 0.49 10.7 7.3 0.12 12.6 2.5 2.3 1 1 1 2 2 2 0 YwiC-like protein NTF2 PF02136.20 KKK23638.1 - 2.6e-31 108.7 0.0 3.4e-31 108.3 0.0 1.1 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Surp PF01805.20 KKK23639.1 - 8.8e-11 41.6 0.0 2.1e-10 40.4 0.0 1.7 1 0 0 1 1 1 1 Surp module Glycos_transf_2 PF00535.26 KKK23642.1 - 4.8e-35 120.9 0.0 5.9e-35 120.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KKK23642.1 - 1.9e-12 47.6 0.0 2.5e-12 47.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 KKK23642.1 - 1.3e-05 24.8 0.0 1.9e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 KKK23642.1 - 0.0017 17.8 0.0 0.0029 17.1 0.0 1.4 1 1 0 1 1 1 1 Glycosyl transferase family 21 Herpes_UL52 PF03121.15 KKK23642.1 - 0.096 12.6 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 Herpesviridae UL52/UL70 DNA primase DUF1749 PF08538.10 KKK23643.1 - 2.1e-108 362.0 0.0 2.3e-108 361.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.7 KKK23643.1 - 1.6e-05 25.7 0.2 1.9e-05 25.4 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family LIDHydrolase PF10230.9 KKK23643.1 - 0.0015 18.2 0.0 0.27 10.7 0.0 2.2 2 0 0 2 2 2 2 Lipid-droplet associated hydrolase DUF900 PF05990.12 KKK23643.1 - 0.013 15.0 0.0 0.022 14.3 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Hydrolase_4 PF12146.8 KKK23643.1 - 0.014 14.6 0.0 0.025 13.9 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KKK23643.1 - 0.1 12.1 0.0 0.27 10.7 0.0 1.7 1 1 0 1 1 1 0 Prolyl oligopeptidase family DUF2974 PF11187.8 KKK23643.1 - 0.21 11.1 0.0 0.32 10.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Ras PF00071.22 KKK23648.1 - 3.2e-51 173.2 0.6 2.3e-50 170.4 0.6 1.9 1 1 0 1 1 1 1 Ras family Roc PF08477.13 KKK23648.1 - 4.5e-18 65.6 0.1 4e-17 62.5 0.1 2.1 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKK23648.1 - 0.00083 18.8 0.1 0.0042 16.5 0.0 1.9 2 0 0 2 2 2 1 ADP-ribosylation factor family FeoB_N PF02421.18 KKK23648.1 - 0.025 14.1 0.2 0.58 9.7 0.0 2.5 2 1 1 3 3 3 0 Ferrous iron transport protein B Septin PF00735.18 KKK23648.1 - 0.12 11.7 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 Septin SRPRB PF09439.10 KKK23648.1 - 0.12 11.8 0.0 0.62 9.5 0.0 1.9 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_25 PF13481.6 KKK23648.1 - 0.12 11.9 0.2 0.32 10.6 0.1 1.8 2 1 0 2 2 2 0 AAA domain HAD_2 PF13419.6 KKK23649.1 - 2.2e-05 24.6 0.0 2.5e-05 24.5 0.0 1.4 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KKK23649.1 - 4.7e-05 23.8 0.0 8.5e-05 22.9 0.0 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KKK23649.1 - 0.00072 19.6 0.0 0.0013 18.8 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Fungal_trans PF04082.18 KKK23650.1 - 0.00019 20.5 0.0 0.00034 19.7 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Ras PF00071.22 KKK23651.1 - 3.2e-55 186.2 0.0 3.6e-55 186.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KKK23651.1 - 3e-21 75.9 0.0 4.3e-21 75.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKK23651.1 - 2.9e-07 30.1 0.0 3.7e-07 29.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RRM_1 PF00076.22 KKK23652.1 - 3.7e-15 55.5 0.0 9.4e-15 54.2 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PCM1_C PF15717.5 KKK23652.1 - 2.2 6.9 33.6 0.15 10.7 27.9 1.7 2 0 0 2 2 2 0 Pericentriolar material 1 C terminus Asp-B-Hydro_N PF05279.11 KKK23652.1 - 5.3 7.0 57.5 6.2 6.8 52.5 2.1 2 0 0 2 2 2 0 Aspartyl beta-hydroxylase N-terminal region POT1PC PF16686.5 KKK23660.1 - 3.6e-44 150.4 0.0 9.2e-44 149.0 0.1 1.7 2 0 0 2 2 2 1 ssDNA-binding domain of telomere protection protein POT1 PF02765.17 KKK23660.1 - 1.1e-24 86.9 0.0 1.2e-18 67.3 0.0 2.5 2 0 0 2 2 2 2 Telomeric single stranded DNA binding POT1/CDC13 SWIRM-assoc_2 PF16496.5 KKK23660.1 - 2.7 6.8 7.2 4 6.2 7.2 1.1 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal Arm PF00514.23 KKK23661.1 - 2.4e-95 310.0 11.9 4.1e-14 52.0 0.0 8.2 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat IBB PF01749.20 KKK23661.1 - 3.6e-27 94.6 3.4 9.4e-27 93.3 3.4 1.7 1 0 0 1 1 1 1 Importin beta binding domain Arm_3 PF16186.5 KKK23661.1 - 8e-24 83.0 3.2 1.8e-23 81.8 3.2 1.6 1 0 0 1 1 1 1 Atypical Arm repeat HEAT_EZ PF13513.6 KKK23661.1 - 7.2e-21 74.3 4.9 1.5e-09 38.2 0.1 6.1 4 1 2 6 6 6 4 HEAT-like repeat HEAT_2 PF13646.6 KKK23661.1 - 1.1e-19 70.6 0.1 4e-09 36.7 0.0 5.0 1 1 4 5 5 5 4 HEAT repeats HEAT PF02985.22 KKK23661.1 - 4.2e-19 67.0 0.3 3.5e-06 26.8 0.0 6.9 7 0 0 7 7 7 4 HEAT repeat Arm_2 PF04826.13 KKK23661.1 - 6.8e-09 35.6 0.0 0.0028 17.2 0.0 4.0 2 1 2 4 4 4 2 Armadillo-like Adaptin_N PF01602.20 KKK23661.1 - 3.2e-06 26.0 0.0 0.00058 18.5 0.0 2.2 1 1 1 2 2 2 2 Adaptin N terminal region V-ATPase_H_C PF11698.8 KKK23661.1 - 1.2e-05 25.4 0.0 0.8 9.8 0.0 4.4 3 2 2 5 5 5 2 V-ATPase subunit H Cnd1 PF12717.7 KKK23661.1 - 0.0019 18.2 0.0 3.9 7.5 0.0 3.1 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_PBS PF03130.16 KKK23661.1 - 0.0092 16.6 4.7 0.77 10.6 0.0 4.6 5 0 0 5 5 5 1 PBS lyase HEAT-like repeat RICTOR_V PF14668.6 KKK23661.1 - 0.013 15.7 3.0 0.98 9.7 0.0 4.6 4 2 2 6 6 6 0 Rapamycin-insensitive companion of mTOR, domain 5 Gcn1_N PF12074.8 KKK23661.1 - 0.038 13.3 0.0 5.7 6.1 0.0 2.7 2 1 1 3 3 3 0 Generalcontrol nonderepressible 1 (Gcn1) N-terminal NopRA1 PF16201.5 KKK23661.1 - 0.09 12.3 0.0 49 3.4 0.0 3.5 1 1 3 4 4 4 0 Nucleolar pre-ribosomal-associated protein 1 Nha1_C PF08619.10 KKK23661.1 - 0.15 11.3 3.5 0.22 10.7 3.5 1.2 1 0 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus TRAP_alpha PF03896.16 KKK23662.1 - 2.1e-13 50.1 1.5 3.5e-13 49.4 1.5 1.4 1 1 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit DUF1616 PF07760.11 KKK23662.1 - 0.02 14.3 0.0 0.028 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1616) PepSY_TM PF03929.16 KKK23662.1 - 0.049 13.3 0.3 0.15 11.7 0.0 1.8 2 1 1 3 3 3 0 PepSY-associated TM region zf-CCCH_2 PF14608.6 KKK23663.1 - 0.0053 17.2 0.6 0.0053 17.2 0.6 2.9 3 0 0 3 3 3 1 RNA-binding, Nab2-type zinc finger Haemadin PF09065.10 KKK23663.1 - 0.034 13.9 4.7 4.4 7.2 0.1 3.0 2 1 0 2 2 2 0 Haemadin zf-CCHH PF10283.9 KKK23663.1 - 0.78 9.8 10.4 3.5 7.7 0.4 3.4 3 0 0 3 3 3 0 PBZ domain HA2 PF04408.23 KKK23664.1 - 6.2e-17 61.8 0.8 2.3e-16 60.0 0.0 2.4 3 0 0 3 3 3 1 Helicase associated domain (HA2) RWD PF05773.22 KKK23664.1 - 1.8e-12 47.6 0.2 5.1e-12 46.1 0.0 2.0 2 0 0 2 2 2 1 RWD domain Helicase_C PF00271.31 KKK23664.1 - 1.8e-12 47.5 0.0 5.1e-12 46.1 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KKK23664.1 - 1.5e-09 37.9 0.1 2.8e-09 37.0 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.16 KKK23664.1 - 3.1e-08 33.9 0.0 6.3e-08 32.9 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold T2SSE PF00437.20 KKK23664.1 - 0.0019 17.3 0.0 0.0038 16.3 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_29 PF13555.6 KKK23664.1 - 0.013 15.2 0.0 0.032 14.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATPase PF06745.13 KKK23664.1 - 0.017 14.5 0.1 0.035 13.5 0.1 1.4 1 0 0 1 1 1 0 KaiC AAA_22 PF13401.6 KKK23664.1 - 0.021 15.1 3.6 0.54 10.5 3.6 2.4 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 KKK23664.1 - 0.03 13.8 0.0 0.057 12.9 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein DND1_DSRM PF14709.7 KKK23664.1 - 0.11 12.8 0.2 0.38 11.0 0.0 2.0 2 0 0 2 2 2 0 double strand RNA binding domain from DEAD END PROTEIN 1 AAA_23 PF13476.6 KKK23664.1 - 0.32 11.5 1.8 0.4 11.2 0.1 1.9 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KKK23664.1 - 1.1 8.9 3.7 0.47 10.2 0.3 2.1 2 1 0 2 2 2 0 AAA domain zf-C2HE PF16278.5 KKK23665.1 - 3.6e-18 65.8 0.4 9.2e-18 64.5 0.4 1.8 1 0 0 1 1 1 1 C2HE / C2H2 / C2HC zinc-binding finger HIT PF01230.23 KKK23665.1 - 1.3e-15 57.9 0.1 3.1e-15 56.7 0.1 1.6 1 1 0 1 1 1 1 HIT domain DcpS_C PF11969.8 KKK23665.1 - 1.7e-15 57.5 6.1 3.4e-14 53.3 6.1 2.2 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding Spc42p PF11544.8 KKK23665.1 - 0.12 12.3 0.2 0.73 9.9 0.0 2.2 2 0 0 2 2 2 0 Spindle pole body component Spc42p Pkinase PF00069.25 KKK23666.1 - 1.9e-17 63.5 0.0 6e-17 61.9 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK23666.1 - 8.2e-08 31.8 0.0 5.2e-07 29.2 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase DUF3433 PF11915.8 KKK23666.1 - 0.051 14.0 0.0 0.19 12.2 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3433) Peptidase_M91 PF14891.6 KKK23667.1 - 0.0045 17.3 2.8 0.0085 16.4 2.8 1.4 1 0 0 1 1 1 1 Effector protein Peptidase_M49 PF03571.15 KKK23668.1 - 3.7e-243 807.9 0.0 5.1e-243 807.4 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M49 SNF5 PF04855.12 KKK23668.1 - 2.9e-87 292.4 0.0 5.9e-87 291.4 0.0 1.5 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 ABC_tran PF00005.27 KKK23670.1 - 3.8e-48 163.5 0.6 4.2e-23 82.4 0.0 3.2 3 0 0 3 3 3 2 ABC transporter ABC_tran_Xtn PF12848.7 KKK23670.1 - 9e-21 73.7 7.9 9e-21 73.7 7.9 3.8 5 0 0 5 5 3 1 ABC transporter AAA_21 PF13304.6 KKK23670.1 - 4.1e-15 56.4 2.2 0.0042 16.9 0.0 4.6 4 1 0 5 5 5 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KKK23670.1 - 9.5e-11 41.5 1.0 0.024 14.1 0.0 4.6 4 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KKK23670.1 - 1.4e-07 32.2 12.0 0.014 15.9 0.0 5.0 5 0 0 5 5 5 2 AAA domain MMR_HSR1 PF01926.23 KKK23670.1 - 2.4e-06 27.6 0.0 0.037 14.1 0.0 3.1 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_22 PF13401.6 KKK23670.1 - 3.3e-06 27.4 0.0 0.023 15.0 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 KKK23670.1 - 4.3e-06 27.3 0.3 0.3 11.6 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_30 PF13604.6 KKK23670.1 - 5.6e-06 26.2 0.3 0.0054 16.5 0.0 3.3 2 1 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 KKK23670.1 - 7.3e-06 26.0 0.9 0.028 14.3 0.0 2.9 2 1 1 3 3 3 2 RsgA GTPase AAA_29 PF13555.6 KKK23670.1 - 1.3e-05 24.9 0.1 0.15 11.8 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 KKK23670.1 - 1.9e-05 25.1 3.5 0.18 12.2 2.2 3.0 2 1 0 2 2 2 2 AAA ATPase domain AAA_33 PF13671.6 KKK23670.1 - 5e-05 23.5 0.3 0.43 10.7 0.0 3.2 2 1 0 2 2 2 2 AAA domain AAA_24 PF13479.6 KKK23670.1 - 0.00022 21.0 0.3 0.85 9.3 0.1 2.9 3 0 0 3 3 2 2 AAA domain AAA_28 PF13521.6 KKK23670.1 - 0.00039 20.7 4.0 0.13 12.5 0.0 3.1 3 0 0 3 3 2 2 AAA domain Dynamin_N PF00350.23 KKK23670.1 - 0.00048 20.2 1.9 0.83 9.7 0.0 4.0 4 0 0 4 4 4 1 Dynamin family AAA_15 PF13175.6 KKK23670.1 - 0.0014 18.4 13.7 0.23 11.1 0.0 4.6 4 1 0 4 4 4 2 AAA ATPase domain AAA PF00004.29 KKK23670.1 - 0.0024 18.3 0.1 2 8.8 0.1 2.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 KKK23670.1 - 0.0034 17.3 0.1 0.88 9.5 0.0 2.6 2 0 0 2 2 2 1 NACHT domain AAA_14 PF13173.6 KKK23670.1 - 0.0091 16.0 0.0 7 6.7 0.0 3.2 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KKK23670.1 - 0.011 16.2 0.0 6.5 7.2 0.0 2.7 2 0 0 2 2 2 0 RNA helicase Rad17 PF03215.15 KKK23670.1 - 0.018 15.0 0.2 1.3 8.9 0.0 3.0 2 1 1 3 3 3 0 Rad17 P-loop domain Zeta_toxin PF06414.12 KKK23670.1 - 0.019 14.2 1.6 5.5 6.2 0.1 3.2 3 0 0 3 3 3 0 Zeta toxin ATP-synt_ab PF00006.25 KKK23670.1 - 0.021 14.5 0.0 0.43 10.2 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain MeaB PF03308.16 KKK23670.1 - 0.022 13.8 2.5 2.3 7.1 0.0 2.7 3 0 0 3 3 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Roc PF08477.13 KKK23670.1 - 0.034 14.4 0.1 7.5 6.8 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase NTPase_1 PF03266.15 KKK23670.1 - 0.048 13.6 0.0 4.2 7.3 0.0 2.7 2 0 0 2 2 2 0 NTPase NB-ARC PF00931.22 KKK23670.1 - 0.067 12.4 0.0 13 4.9 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain AAA_5 PF07728.14 KKK23670.1 - 0.068 13.2 0.3 10 6.1 0.0 2.8 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 KKK23670.1 - 0.069 12.7 0.0 7.5 6.0 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region TsaE PF02367.17 KKK23670.1 - 0.096 12.7 0.0 13 5.8 0.0 2.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE cobW PF02492.19 KKK23670.1 - 0.1 12.2 3.2 2.2 7.8 0.5 2.9 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_27 PF13514.6 KKK23670.1 - 0.1 12.2 5.8 4.3 6.9 0.0 3.7 5 0 0 5 5 2 0 AAA domain PduV-EutP PF10662.9 KKK23670.1 - 0.15 11.8 0.0 23 4.7 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF87 PF01935.17 KKK23670.1 - 0.42 10.7 7.2 11 6.1 0.0 4.1 5 0 0 5 5 4 0 Helicase HerA, central domain PRK PF00485.18 KKK23670.1 - 0.45 10.2 2.4 2.2 8.0 0.0 3.1 4 0 0 4 4 4 0 Phosphoribulokinase / Uridine kinase family Sugar_tr PF00083.24 KKK23671.1 - 5.8e-50 170.5 16.4 1.8e-29 103.0 5.5 4.0 2 1 2 4 4 4 4 Sugar (and other) transporter MFS_1 PF07690.16 KKK23671.1 - 0.0026 16.7 30.0 0.0069 15.3 10.5 2.6 2 1 0 2 2 2 2 Major Facilitator Superfamily Erythrovirus_X PF06795.11 KKK23671.1 - 0.053 13.8 0.4 0.98 9.8 0.1 2.4 2 0 0 2 2 2 0 Erythrovirus X protein WD40 PF00400.32 KKK23672.1 - 3.1e-25 87.9 23.9 2.9e-05 24.7 0.5 7.0 6 2 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKK23672.1 - 1.2e-11 44.8 7.9 0.00071 19.8 0.4 4.5 3 2 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain TFIIIC_delta PF12657.7 KKK23672.1 - 1.8e-05 24.8 10.4 0.73 9.7 6.3 3.1 1 1 1 2 2 2 2 Transcription factor IIIC subunit delta N-term MFS_1 PF07690.16 KKK23674.1 - 1.3e-42 146.0 30.5 1.3e-42 146.0 30.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KKK23674.1 - 2.9e-13 49.5 6.4 2.9e-13 49.5 6.4 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter RRN3 PF05327.11 KKK23697.1 - 3e-180 600.5 1.7 9.8e-180 598.8 0.0 1.9 1 1 1 2 2 2 1 RNA polymerase I specific transcription initiation factor RRN3 Abhydrolase_3 PF07859.13 KKK23698.1 - 2.5e-45 154.9 2.7 3.9e-44 151.0 2.7 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KKK23698.1 - 3.9e-08 32.6 0.9 1.6e-07 30.6 0.9 1.7 1 1 0 1 1 1 1 Carboxylesterase family Esterase_phd PF10503.9 KKK23698.1 - 0.029 13.9 1.2 0.13 11.7 0.5 2.0 2 0 0 2 2 2 0 Esterase PHB depolymerase Abhydrolase_2 PF02230.16 KKK23698.1 - 0.062 13.1 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Esterase PF00756.20 KKK23698.1 - 0.1 12.2 0.0 0.26 10.9 0.0 1.6 1 1 0 1 1 1 0 Putative esterase WD40 PF00400.32 KKK23699.1 - 9.6e-18 64.2 5.4 0.0043 17.9 0.0 5.4 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKK23699.1 - 3.1e-06 27.4 0.4 0.016 15.5 0.1 4.5 4 1 1 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KKK23699.1 - 7.4e-06 24.9 1.4 0.00051 18.8 0.2 2.7 2 1 1 3 3 3 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 KKK23699.1 - 0.022 13.5 0.0 2.8 6.6 0.0 2.8 2 1 1 3 3 3 0 Nup133 N terminal like DUF1615 PF07759.12 KKK23699.1 - 0.087 12.0 1.8 0.14 11.3 1.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1615) Astro_capsid_p PF12226.8 KKK23699.1 - 4.6 6.3 16.4 8.7 5.4 16.4 1.4 1 0 0 1 1 1 0 Turkey astrovirus capsid protein BUD22 PF09073.10 KKK23699.1 - 5.2 6.3 20.1 6 6.1 17.5 1.9 2 0 0 2 2 2 0 BUD22 Fcf1 PF04900.12 KKK23701.1 - 7.9e-19 67.9 0.0 3.1e-10 40.3 0.0 2.5 2 0 0 2 2 2 2 Fcf1 Cmc1 PF08583.10 KKK23702.1 - 2.2e-17 62.8 5.1 2.6e-17 62.6 5.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like ProSAAS PF07259.12 KKK23702.1 - 0.11 12.4 0.1 0.12 12.3 0.1 1.1 1 0 0 1 1 1 0 ProSAAS precursor Redoxin PF08534.10 KKK23711.1 - 3.3e-25 88.5 0.0 4.3e-25 88.1 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 KKK23711.1 - 1.3e-06 28.3 0.0 1.8e-06 27.9 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family BolA PF01722.18 KKK23712.1 - 6.6e-19 68.0 0.1 2.5e-18 66.1 0.0 1.9 2 1 0 2 2 2 1 BolA-like protein Ion_trans PF00520.31 KKK23713.1 - 6.7e-121 402.1 86.1 3.5e-40 137.8 8.0 5.0 4 1 0 4 4 4 4 Ion transport protein GPHH PF16905.5 KKK23713.1 - 0.00055 19.7 0.0 0.0012 18.5 0.0 1.6 1 0 0 1 1 1 1 Voltage-dependent L-type calcium channel, IQ-associated EF-hand_1 PF00036.32 KKK23713.1 - 0.0013 18.2 0.0 0.0036 16.8 0.0 1.8 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 KKK23713.1 - 0.0025 18.2 0.0 0.013 15.9 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 KKK23713.1 - 0.0045 16.8 0.0 0.02 14.8 0.0 2.1 1 0 0 1 1 1 1 EF-hand domain KH_1 PF00013.29 KKK23718.1 - 4e-25 87.4 3.5 5.2e-07 29.4 0.1 6.5 7 0 0 7 7 7 4 KH domain MMR_HSR1_Xtn PF16897.5 KKK23718.1 - 0.24 11.4 1.8 1.7 8.7 0.3 2.7 2 0 0 2 2 2 0 C-terminal region of MMR_HSR1 domain MRP-L28 PF09812.9 KKK23719.1 - 1e-05 25.7 0.1 1.6e-05 25.1 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 RINGv PF12906.7 KKK23719.1 - 7.1e-05 22.8 7.3 0.00013 22.0 7.3 1.4 1 0 0 1 1 1 1 RING-variant domain FANCL_C PF11793.8 KKK23719.1 - 0.00019 21.5 3.3 0.00037 20.6 3.3 1.4 1 0 0 1 1 1 1 FANCL C-terminal domain zf-RING_2 PF13639.6 KKK23719.1 - 0.26 11.7 6.1 0.49 10.8 6.1 1.5 1 0 0 1 1 1 0 Ring finger domain GalKase_gal_bdg PF10509.9 KKK23720.1 - 2.2e-19 68.7 0.0 3.9e-19 67.9 0.0 1.4 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.26 KKK23720.1 - 6.3e-15 55.2 1.1 1.4e-14 54.1 1.1 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KKK23720.1 - 9.6e-13 48.3 0.0 2.2e-12 47.2 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal HTH_37 PF13744.6 KKK23720.1 - 0.049 13.6 0.2 0.25 11.3 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_3 PF01381.22 KKK23720.1 - 0.14 12.2 0.2 0.75 9.9 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix TPP_enzyme_N PF02776.18 KKK23721.1 - 1.1e-55 187.8 0.0 4.5e-54 182.6 0.0 2.5 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 KKK23721.1 - 1e-49 168.3 0.1 1.5e-47 161.2 0.0 3.1 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 KKK23721.1 - 3.2e-38 130.6 0.1 5.4e-38 129.8 0.1 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain POR_N PF01855.19 KKK23721.1 - 0.08 12.7 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg Annexin PF00191.20 KKK23728.1 - 7.4e-49 163.7 0.4 6.5e-19 67.8 0.0 3.4 3 0 0 3 3 3 3 Annexin Glyco_hydro_61 PF03443.14 KKK23729.1 - 1.7e-58 198.0 0.0 1.7e-58 198.0 0.0 1.9 2 1 0 2 2 2 1 Glycosyl hydrolase family 61 CBM_1 PF00734.18 KKK23729.1 - 1.3e-12 47.4 6.2 3e-12 46.2 6.2 1.7 1 0 0 1 1 1 1 Fungal cellulose binding domain Glyco_transf_28 PF03033.20 KKK23730.1 - 5.2e-18 65.4 0.1 3e-12 46.7 0.0 2.4 2 0 0 2 2 2 2 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 KKK23730.1 - 1.3e-05 24.2 0.0 2.3e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase ATG_C PF09333.11 KKK23730.1 - 3.1e-05 24.2 0.0 9.7e-05 22.6 0.0 1.8 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain Glyco_tran_28_C PF04101.16 KKK23730.1 - 0.016 15.2 0.0 0.03 14.3 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain AF-4 PF05110.13 KKK23730.1 - 8.5 4.3 9.2 12 3.8 9.2 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Cation_efflux PF01545.21 KKK23731.1 - 6.8e-54 182.6 0.5 1.1e-53 181.9 0.5 1.3 1 1 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 KKK23731.1 - 0.0055 16.8 0.5 0.011 15.8 0.5 1.5 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter PI-PLC-X PF00388.19 KKK23734.1 - 2.5e-60 202.3 0.0 4.4e-60 201.5 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 KKK23734.1 - 7.5e-44 148.7 0.4 7.4e-42 142.3 0.1 2.5 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, Y domain GDPD PF03009.17 KKK23734.1 - 0.0063 16.3 0.0 0.023 14.4 0.0 1.8 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family EF-hand_1 PF00036.32 KKK23734.1 - 0.012 15.1 0.6 0.062 12.9 0.1 2.4 2 0 0 2 2 2 0 EF hand EF-hand_like PF09279.11 KKK23734.1 - 0.013 15.9 0.1 0.03 14.8 0.1 1.6 1 0 0 1 1 1 0 Phosphoinositide-specific phospholipase C, efhand-like Colicin_Pyocin PF01320.18 KKK23734.1 - 0.17 12.0 0.1 0.48 10.6 0.1 1.8 1 0 0 1 1 1 0 Colicin immunity protein / pyocin immunity protein EF-hand_7 PF13499.6 KKK23734.1 - 0.31 11.5 2.4 1.2 9.6 2.4 2.1 1 1 0 1 1 1 0 EF-hand domain pair WD40 PF00400.32 KKK23735.1 - 1.7e-16 60.3 6.1 1.4e-06 28.9 0.3 5.9 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKK23735.1 - 1.9e-08 34.5 0.0 0.00036 20.8 0.0 3.8 3 2 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 KKK23735.1 - 0.0014 17.3 0.0 2.1 6.8 0.0 3.2 2 2 1 3 3 3 2 Cytochrome D1 heme domain Frtz PF11768.8 KKK23735.1 - 0.046 12.0 0.0 0.071 11.4 0.0 1.2 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz WDCP PF15390.6 KKK23735.1 - 0.053 11.9 0.5 0.092 11.1 0.0 1.5 2 0 0 2 2 2 0 WD repeat and coiled-coil-containing protein family DUF5122 PF17164.4 KKK23735.1 - 0.096 13.0 0.3 27 5.1 0.1 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5122) beta-propeller DUF1308 PF07000.11 KKK23736.1 - 3.1e-13 50.0 0.1 2.1e-11 44.0 0.1 2.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1308) DUF5614 PF18474.1 KKK23736.1 - 0.041 13.2 0.1 2.3 7.5 0.0 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5614) Allexi_40kDa PF05549.11 KKK23736.1 - 0.077 12.5 0.0 0.16 11.4 0.0 1.5 1 0 0 1 1 1 0 Allexivirus 40kDa protein Cwf_Cwc_15 PF04889.12 KKK23736.1 - 3.9 7.1 15.7 4.3 7.0 12.7 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Ribonuc_red_sm PF00268.21 KKK23737.1 - 1.6e-121 405.0 1.2 2e-121 404.8 1.2 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain Mito_carr PF00153.27 KKK23738.1 - 1.4e-53 178.8 4.9 9.7e-19 67.1 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein SRP9-21 PF05486.12 KKK23739.1 - 3.3e-32 110.8 0.5 3.3e-32 110.8 0.5 1.5 2 0 0 2 2 2 1 Signal recognition particle 9 kDa protein (SRP9) F-box-like PF12937.7 KKK23743.1 - 1.3e-09 37.8 1.9 1.2e-06 28.3 0.2 2.6 2 0 0 2 2 2 2 F-box-like F-box PF00646.33 KKK23743.1 - 8.5e-07 28.7 0.6 0.032 14.1 0.0 2.7 2 0 0 2 2 2 2 F-box domain DAHP_synth_1 PF00793.20 KKK23744.1 - 1.2e-98 329.3 0.0 2e-98 328.7 0.0 1.2 1 0 0 1 1 1 1 DAHP synthetase I family EBP PF05241.12 KKK23744.1 - 8.6e-51 171.9 7.9 1.2e-50 171.4 7.9 1.2 1 0 0 1 1 1 1 Emopamil binding protein AIG2_2 PF13772.6 KKK23745.1 - 0.00083 19.7 0.7 0.0061 16.9 0.2 2.6 2 1 0 2 2 2 1 AIG2-like family Cytochrom_C1 PF02167.15 KKK23746.1 - 3.9e-92 307.9 0.0 5e-92 307.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.6 KKK23746.1 - 0.021 15.1 0.0 0.047 14.0 0.0 1.6 1 0 0 1 1 1 0 Cytochrome C oxidase, cbb3-type, subunit III Sec10 PF07393.11 KKK23747.1 - 1.9e-181 605.1 3.5 2.2e-181 604.9 3.5 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 F-box-like PF12937.7 KKK23747.1 - 2.9e-05 23.9 0.0 9.2e-05 22.3 0.1 1.8 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KKK23747.1 - 0.00099 18.9 0.1 0.0022 17.8 0.1 1.6 1 0 0 1 1 1 1 F-box domain FlhD PF05247.13 KKK23747.1 - 0.026 14.8 0.0 0.07 13.4 0.0 1.7 1 0 0 1 1 1 0 Flagellar transcriptional activator (FlhD) F-box_4 PF15966.5 KKK23747.1 - 0.13 12.2 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 F-box CAP PF00188.26 KKK23748.1 - 6.2e-19 69.1 4.5 1.1e-18 68.2 4.5 1.5 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Cullin PF00888.22 KKK23748.1 - 0.25 9.9 0.1 0.31 9.6 0.1 1.0 1 0 0 1 1 1 0 Cullin family Chromo PF00385.24 KKK23749.1 - 3.9e-07 29.9 0.4 3.9e-07 29.9 0.4 2.2 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Mito_carr PF00153.27 KKK23750.1 - 3.5e-66 219.2 0.3 3.3e-22 78.2 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein LapA_dom PF06305.11 KKK23750.1 - 0.053 13.3 0.2 3.5 7.5 0.0 2.6 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain SLX9 PF15341.6 KKK23751.1 - 3e-36 124.7 10.1 4e-36 124.3 10.1 1.2 1 0 0 1 1 1 1 Ribosome biogenesis protein SLX9 Neugrin PF06413.11 KKK23751.1 - 0.016 15.2 5.2 0.28 11.1 1.7 2.1 1 1 1 2 2 2 0 Neugrin HrpJ PF07201.11 KKK23751.1 - 0.077 13.3 2.8 0.16 12.3 2.8 1.5 1 1 0 1 1 1 0 HrpJ-like domain Brix PF04427.18 KKK23752.1 - 1.2e-31 110.3 0.0 3.8e-31 108.7 0.0 1.8 2 0 0 2 2 2 1 Brix domain F-box-like PF12937.7 KKK23752.1 - 0.00034 20.4 0.1 0.00079 19.3 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KKK23752.1 - 0.0042 16.9 0.5 0.011 15.6 0.5 1.7 1 0 0 1 1 1 1 F-box domain DUF4817 PF16087.5 KKK23752.1 - 0.024 14.5 0.3 9.7 6.1 0.0 3.0 2 0 0 2 2 2 0 Helix-turn-helix domain (DUF4817) PBP1_TM PF14812.6 KKK23752.1 - 0.1 13.0 2.0 0.3 11.5 2.0 1.8 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal AAA_2 PF07724.14 KKK23753.1 - 4.2e-39 134.4 0.0 4.4e-38 131.1 0.0 2.6 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.29 KKK23753.1 - 8.2e-15 55.4 0.0 1.6e-14 54.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 KKK23753.1 - 2.9e-08 33.6 0.0 8.1e-08 32.2 0.0 1.7 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 KKK23753.1 - 2.6e-06 27.5 0.0 5.8e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 KKK23753.1 - 7.8e-05 22.4 0.0 0.024 14.3 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain Mg_chelatase PF01078.21 KKK23753.1 - 0.00022 20.7 0.2 0.014 14.8 0.0 3.0 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 KKK23753.1 - 0.00043 20.6 0.5 0.01 16.1 0.5 2.5 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KKK23753.1 - 0.0014 19.0 0.2 0.014 15.8 0.1 2.3 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 KKK23753.1 - 0.0037 17.0 0.1 0.053 13.3 0.0 2.4 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_24 PF13479.6 KKK23753.1 - 0.0049 16.6 0.0 0.0084 15.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KKK23753.1 - 0.0053 16.5 0.0 0.01 15.6 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Sigma54_activ_2 PF14532.6 KKK23753.1 - 0.025 14.7 0.0 0.14 12.3 0.0 2.1 2 1 0 2 2 2 0 Sigma-54 interaction domain AAA_7 PF12775.7 KKK23753.1 - 0.047 13.2 0.0 0.087 12.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region NACHT PF05729.12 KKK23753.1 - 0.051 13.5 0.0 1.7 8.5 0.0 2.3 2 0 0 2 2 2 0 NACHT domain MCM PF00493.23 KKK23753.1 - 0.054 12.6 0.1 0.11 11.6 0.1 1.5 1 0 0 1 1 1 0 MCM P-loop domain RNA_helicase PF00910.22 KKK23753.1 - 0.061 13.7 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.6 KKK23753.1 - 0.061 13.9 0.0 0.14 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 KKK23753.1 - 0.07 13.1 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 KKK23753.1 - 0.086 12.9 0.0 0.19 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 KKK23753.1 - 0.1 12.5 0.0 0.27 11.1 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 KKK23753.1 - 0.17 12.1 0.4 1.5 9.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain Ras PF00071.22 KKK23754.1 - 1.3e-63 213.4 0.2 1.6e-63 213.2 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KKK23754.1 - 1.2e-35 122.3 0.2 1.7e-35 121.8 0.2 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKK23754.1 - 3e-13 49.6 0.1 3.9e-13 49.2 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KKK23754.1 - 5.6e-08 32.9 0.1 8.6e-08 32.3 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KKK23754.1 - 8.1e-05 22.6 0.2 0.015 15.2 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 KKK23754.1 - 0.00043 19.9 0.1 0.0022 17.6 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KKK23754.1 - 0.00043 19.7 0.1 0.00071 19.0 0.1 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.6 KKK23754.1 - 0.0026 18.0 0.0 0.02 15.1 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KKK23754.1 - 0.011 16.2 0.0 0.017 15.5 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_14 PF13173.6 KKK23754.1 - 0.013 15.5 0.2 0.041 13.9 0.1 1.9 1 1 0 1 1 1 0 AAA domain SRPRB PF09439.10 KKK23754.1 - 0.017 14.5 0.0 0.03 13.8 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit ABC_tran PF00005.27 KKK23754.1 - 0.021 15.3 0.2 0.028 14.9 0.2 1.5 1 1 0 1 1 1 0 ABC transporter AAA_24 PF13479.6 KKK23754.1 - 0.027 14.2 0.1 0.062 13.0 0.1 1.7 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 KKK23754.1 - 0.059 12.8 0.0 0.17 11.3 0.0 1.7 2 0 0 2 2 2 0 Bacterial TniB protein AAA_21 PF13304.6 KKK23754.1 - 0.1 12.4 0.8 0.17 11.7 0.6 1.5 1 1 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system FeoB_N PF02421.18 KKK23754.1 - 0.1 12.1 0.1 0.23 11.0 0.0 1.6 2 0 0 2 2 2 0 Ferrous iron transport protein B MCM PF00493.23 KKK23754.1 - 0.11 11.6 0.0 0.23 10.5 0.0 1.5 1 1 0 1 1 1 0 MCM P-loop domain AAA_7 PF12775.7 KKK23754.1 - 0.12 11.9 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_5 PF07728.14 KKK23754.1 - 0.14 12.1 0.0 0.31 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RSN1_7TM PF02714.15 KKK23755.1 - 5.5e-81 271.9 20.2 1.3e-80 270.6 20.2 1.7 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 KKK23755.1 - 1.1e-45 156.0 0.0 1.6e-45 155.5 0.0 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 KKK23755.1 - 7.1e-42 142.8 0.9 7.1e-42 142.8 0.9 2.7 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport Anoctamin PF04547.12 KKK23755.1 - 3.1 6.5 10.7 0.017 14.0 0.8 2.2 2 1 0 2 2 2 0 Calcium-activated chloride channel hDGE_amylase PF14701.6 KKK23756.1 - 1.2e-178 594.7 0.1 1.6e-178 594.3 0.1 1.1 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain GDE_C PF06202.14 KKK23756.1 - 6.3e-116 387.5 0.0 1.4e-115 386.3 0.0 1.5 2 0 0 2 2 2 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.6 KKK23756.1 - 4.1e-85 285.5 0.0 8.1e-85 284.5 0.0 1.5 1 0 0 1 1 1 1 Central domain of human glycogen debranching enzyme hGDE_N PF14699.6 KKK23756.1 - 1e-30 105.7 0.0 3e-30 104.2 0.0 1.9 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme Alpha-amylase PF00128.24 KKK23756.1 - 0.081 12.5 0.1 0.19 11.2 0.1 1.6 1 0 0 1 1 1 0 Alpha amylase, catalytic domain NAD_Gly3P_dh_N PF01210.23 KKK23757.1 - 1.3e-46 158.4 0.0 2.1e-46 157.8 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.14 KKK23757.1 - 8.1e-43 146.1 0.1 1.3e-42 145.4 0.1 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus PfkB PF00294.24 KKK23758.1 - 8.4e-19 68.0 0.0 2.3e-18 66.5 0.0 1.6 1 1 0 1 1 1 1 pfkB family carbohydrate kinase CVNH PF08881.10 KKK23760.1 - 6.6e-26 91.0 0.1 7.3e-26 90.8 0.1 1.0 1 0 0 1 1 1 1 CVNH domain ETX_MTX2 PF03318.13 KKK23760.1 - 0.053 13.3 0.1 0.082 12.7 0.1 1.2 1 0 0 1 1 1 0 Clostridium epsilon toxin ETX/Bacillus mosquitocidal toxin MTX2 UBA2_C PF16195.5 KKK23763.1 - 3.4 8.4 13.1 0.085 13.6 5.0 2.4 2 2 0 2 2 2 0 SUMO-activating enzyme subunit 2 C-terminus F-box-like PF12937.7 KKK23765.1 - 0.0026 17.6 0.8 0.0058 16.5 0.8 1.6 1 0 0 1 1 1 1 F-box-like LRR_1 PF00560.33 KKK23765.1 - 5.3 8.0 5.4 6.6 7.7 1.6 3.3 2 0 0 2 2 2 0 Leucine Rich Repeat LRR_4 PF12799.7 KKK23765.1 - 5.7 7.5 10.4 0.16 12.4 0.7 3.6 5 0 0 5 5 5 0 Leucine Rich repeats (2 copies) Abp2 PF09441.10 KKK23766.1 - 5.1e-87 290.3 0.1 7.4e-87 289.8 0.1 1.2 1 0 0 1 1 1 1 ARS binding protein 2 TrkA_N PF02254.18 KKK23771.1 - 0.25 11.6 0.0 0.44 10.8 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain DUF3844 PF12955.7 KKK23772.1 - 1.2e-35 121.8 2.9 2e-35 121.1 2.9 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3844) Ceramidase_alk PF04734.13 KKK23772.1 - 0.026 13.2 2.1 0.037 12.7 2.1 1.1 1 0 0 1 1 1 0 Neutral/alkaline non-lysosomal ceramidase, N-terminal CKS PF01111.19 KKK23773.1 - 8.1e-35 118.9 0.5 1.2e-34 118.4 0.5 1.2 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit Thioredoxin_4 PF13462.6 KKK23774.1 - 6.7e-07 29.6 0.0 9.2e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Phage_TAC_6 PF09550.10 KKK23774.1 - 0.043 14.2 0.1 0.13 12.8 0.1 1.7 2 0 0 2 2 2 0 Phage tail assembly chaperone protein, TAC DSBA PF01323.20 KKK23774.1 - 0.12 12.1 1.3 4.7 6.9 0.2 2.3 1 1 0 2 2 2 0 DSBA-like thioredoxin domain ANAPC_CDC26 PF10471.9 KKK23775.1 - 2.7e-10 40.9 1.1 1e-09 39.1 1.1 1.8 1 1 0 1 1 1 1 Anaphase-promoting complex APC subunit CDC26 Aldedh PF00171.22 KKK23777.1 - 2e-156 521.1 0.0 2.3e-156 520.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family GMC_oxred_N PF00732.19 KKK23778.1 - 1.5e-49 169.0 0.0 2e-49 168.6 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KKK23778.1 - 7.6e-40 136.8 0.0 1.2e-39 136.2 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KKK23778.1 - 2.1e-06 27.1 0.0 0.042 12.9 0.0 2.4 3 0 0 3 3 3 2 FAD binding domain Lycopene_cycl PF05834.12 KKK23778.1 - 0.00014 21.0 0.0 0.00021 20.5 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 KKK23778.1 - 0.00054 20.1 0.1 0.0014 18.8 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KKK23778.1 - 0.0025 17.5 0.6 0.019 14.6 0.2 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KKK23778.1 - 0.0028 16.9 0.0 0.0091 15.3 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KKK23778.1 - 0.0094 15.3 0.4 0.1 11.9 0.0 2.2 2 1 0 2 2 2 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 KKK23778.1 - 0.031 13.2 0.0 0.043 12.7 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox PF00070.27 KKK23778.1 - 0.053 14.1 0.2 1.3 9.6 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KKK23778.1 - 0.12 11.6 0.1 0.51 9.5 0.0 2.0 2 0 0 2 2 2 0 Thi4 family FeS_assembly_P PF01883.19 KKK23779.1 - 8.3e-09 35.5 0.0 2.8e-08 33.8 0.0 1.9 1 1 0 1 1 1 1 Iron-sulfur cluster assembly protein Pheromone PF08015.11 KKK23779.1 - 0.64 11.1 3.5 5.6 8.1 0.0 2.7 3 0 0 3 3 3 0 Fungal mating-type pheromone Fungal_trans PF04082.18 KKK23780.1 - 1.8e-07 30.5 0.2 2.8e-07 29.8 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK23780.1 - 5.9e-07 29.5 8.1 1.1e-06 28.6 8.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RRF PF01765.19 KKK23781.1 - 4.2e-23 82.1 0.2 6.2e-23 81.5 0.2 1.2 1 0 0 1 1 1 1 Ribosome recycling factor HSP70 PF00012.20 KKK23782.1 - 1.5e-225 749.9 8.2 1.7e-225 749.8 8.2 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KKK23782.1 - 1.4e-16 60.3 0.1 1.5e-15 56.9 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 KKK23782.1 - 0.00056 19.7 0.0 0.0013 18.5 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DDR PF08841.10 KKK23782.1 - 0.014 14.4 0.1 0.29 10.1 0.1 2.4 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain HEPPP_synt_1 PF07307.11 KKK23782.1 - 0.097 12.3 0.1 5 6.7 0.0 2.4 2 0 0 2 2 2 0 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 Glyco_hydro_3 PF00933.21 KKK23783.1 - 1.3e-67 228.4 0.0 1.8e-67 228.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Acetyltransf_1 PF00583.25 KKK23783.1 - 4.1e-05 23.8 0.0 0.00012 22.3 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Glyco_hydro_3_C PF01915.22 KKK23783.1 - 0.0025 17.8 0.0 0.005 16.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glucosamine_iso PF01182.20 KKK23784.1 - 4e-20 72.7 0.0 6.8e-20 71.9 0.0 1.3 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Sugar-bind PF04198.13 KKK23784.1 - 0.078 12.1 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 Putative sugar-binding domain CPSF_A PF03178.15 KKK23785.1 - 9.1e-111 370.2 0.0 3.6e-110 368.3 0.0 2.0 2 0 0 2 2 2 1 CPSF A subunit region NDT80_PhoG PF05224.12 KKK23786.1 - 2e-37 129.2 0.6 7.5e-37 127.4 0.6 2.0 1 1 0 1 1 1 1 NDT80 / PhoG like DNA-binding family Macoilin PF09726.9 KKK23786.1 - 0.29 9.6 1.3 0.38 9.2 1.3 1.1 1 0 0 1 1 1 0 Macoilin family Herpes_LMP2 PF07415.11 KKK23786.1 - 9.1 4.9 5.7 12 4.5 5.7 1.1 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein LemA PF04011.12 KKK23787.1 - 0.026 14.4 0.2 0.032 14.1 0.2 1.3 1 0 0 1 1 1 0 LemA family Barstar PF01337.18 KKK23787.1 - 0.13 12.4 0.3 1.9 8.6 0.0 2.2 2 0 0 2 2 2 0 Barstar (barnase inhibitor) LMBR1 PF04791.16 KKK23788.1 - 2.4e-20 72.9 21.4 3.2e-17 62.6 21.4 2.3 1 1 0 1 1 1 1 LMBR1-like membrane protein DUF2040 PF09745.9 KKK23788.1 - 0.78 9.8 4.6 0.14 12.2 0.8 1.6 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 55 (DUF2040) Zip PF02535.22 KKK23789.1 - 6.2e-34 117.7 0.1 1e-33 117.0 0.1 1.3 1 1 0 1 1 1 1 ZIP Zinc transporter COS PF18568.1 KKK23789.1 - 0.08 12.9 0.1 0.2 11.6 0.1 1.6 1 0 0 1 1 1 0 TRIM C-terminal subgroup One Signature domain Atg14 PF10186.9 KKK23790.1 - 2.5e-75 253.5 0.7 3.4e-75 253.1 0.7 1.1 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 GTP_EFTU PF00009.27 KKK23791.1 - 1.1e-46 158.8 0.0 1.6e-46 158.3 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFTUD2 PF16004.5 KKK23791.1 - 1.6e-38 132.0 10.3 3e-38 131.1 10.3 1.5 1 0 0 1 1 1 1 116 kDa U5 small nuclear ribonucleoprotein component N-terminus EFG_IV PF03764.18 KKK23791.1 - 3.8e-24 84.8 0.0 1.2e-23 83.2 0.0 1.9 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 KKK23791.1 - 4.5e-20 71.5 0.0 1.2e-19 70.2 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KKK23791.1 - 1.9e-11 44.2 0.0 4.8e-11 42.9 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 KKK23791.1 - 2.6e-07 30.6 0.1 7.4e-07 29.2 0.0 1.8 2 0 0 2 2 2 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 KKK23791.1 - 2.8e-05 24.2 0.1 5.2e-05 23.3 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 KKK23791.1 - 0.062 12.7 0.1 0.43 10.0 0.1 2.2 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Septin PF00735.18 KKK23791.1 - 0.091 12.0 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 Septin DUF5505 PF17610.2 KKK23791.1 - 0.13 12.3 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5505) Thiolase_N PF00108.23 KKK23792.1 - 4.5e-93 311.4 1.5 5.8e-93 311.0 0.2 1.7 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KKK23792.1 - 8.4e-45 151.4 3.3 1.3e-44 150.8 2.6 1.7 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KKK23792.1 - 3.3e-05 23.6 4.5 4.2e-05 23.3 2.9 2.0 2 1 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 KKK23792.1 - 0.028 14.3 3.3 0.39 10.6 0.1 3.0 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III tRNA-synt_2c PF01411.19 KKK23794.1 - 1.7e-217 723.4 0.1 2.5e-217 722.8 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 KKK23794.1 - 5.1e-17 61.7 0.4 1.2e-16 60.5 0.4 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 KKK23794.1 - 3.1e-13 50.3 2.9 6.2e-13 49.3 0.2 2.6 2 0 0 2 2 2 1 DHHA1 domain SH3BGR PF04908.15 KKK23794.1 - 0.12 12.6 0.1 0.36 11.0 0.1 1.8 1 0 0 1 1 1 0 SH3-binding, glutamic acid-rich protein Pro_isomerase PF00160.21 KKK23795.1 - 1.9e-50 171.2 0.5 2.3e-50 170.9 0.5 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD zf-RING_2 PF13639.6 KKK23796.1 - 1.9e-13 50.5 2.9 3e-13 49.9 2.9 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KKK23796.1 - 1.1e-10 41.2 2.3 1.7e-10 40.6 2.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KKK23796.1 - 9.4e-09 34.9 1.3 1.7e-08 34.1 1.3 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 KKK23796.1 - 1.5e-08 34.3 0.9 2.5e-08 33.6 0.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KKK23796.1 - 2.3e-07 31.0 6.9 1.4e-06 28.5 6.9 2.1 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KKK23796.1 - 8e-07 28.9 0.7 1.2e-06 28.3 0.7 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KKK23796.1 - 7.7e-06 25.8 0.3 4.2e-05 23.5 0.0 2.2 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KKK23796.1 - 0.00023 21.0 0.5 0.00038 20.2 0.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KKK23796.1 - 0.00026 21.0 1.4 0.0008 19.4 1.4 1.8 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 KKK23796.1 - 0.0016 18.6 1.7 0.0042 17.2 1.7 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Zn_ribbon_17 PF17120.5 KKK23796.1 - 0.0016 18.0 1.7 0.0028 17.2 1.7 1.3 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 KKK23796.1 - 0.0064 16.3 2.9 0.015 15.1 2.9 1.6 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 KKK23796.1 - 0.0091 15.8 3.0 0.015 15.0 3.0 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain PHD PF00628.29 KKK23796.1 - 0.0092 15.8 2.3 0.016 15.1 2.3 1.4 1 0 0 1 1 1 1 PHD-finger RINGv PF12906.7 KKK23796.1 - 0.039 14.1 1.2 0.083 13.0 1.2 1.6 1 1 0 1 1 1 0 RING-variant domain Prok-RING_1 PF14446.6 KKK23796.1 - 0.22 11.5 4.0 0.18 11.7 0.9 2.0 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-RING_10 PF16685.5 KKK23796.1 - 0.23 11.6 1.0 0.39 10.9 1.0 1.3 1 0 0 1 1 1 0 zinc RING finger of MSL2 FANCL_C PF11793.8 KKK23796.1 - 0.24 11.6 3.0 0.72 10.1 3.0 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING-like PF08746.11 KKK23796.1 - 0.31 11.4 2.1 0.57 10.5 2.1 1.5 1 0 0 1 1 1 0 RING-like domain zf-C3H2C3 PF17122.5 KKK23796.1 - 0.38 10.8 3.6 0.38 10.8 1.8 1.9 2 1 0 2 2 1 0 Zinc-finger DUF3517 PF12030.8 KKK23828.1 - 6.5e-105 350.8 0.0 1.1e-104 349.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3517) UCH PF00443.29 KKK23828.1 - 4.1e-41 141.2 0.3 7.6e-41 140.3 0.3 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KKK23828.1 - 1.1e-22 81.0 0.1 2.3e-22 80.0 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Sec23_helical PF04815.15 KKK23828.1 - 0.13 12.1 0.0 0.79 9.6 0.0 2.4 1 0 0 1 1 1 0 Sec23/Sec24 helical domain PCI PF01399.27 KKK23841.1 - 1.7e-20 73.5 0.1 5.5e-20 71.8 0.1 1.9 1 0 0 1 1 1 1 PCI domain TPR_2 PF07719.17 KKK23841.1 - 0.0041 17.1 3.3 0.23 11.7 0.1 4.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 KKK23841.1 - 0.0053 16.5 0.9 0.47 10.4 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 KKK23841.1 - 0.014 15.3 0.6 1.2 9.3 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 KKK23841.1 - 0.042 13.5 0.5 0.25 11.1 0.1 2.6 2 0 0 2 2 2 0 TPR repeat ParD_antitoxin PF03693.14 KKK23841.1 - 0.14 12.6 0.0 0.68 10.4 0.0 2.1 2 0 0 2 2 2 0 Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH TPR_12 PF13424.6 KKK23841.1 - 0.16 12.3 0.7 9 6.7 0.0 3.6 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 KKK23841.1 - 0.61 11.1 2.9 23 6.2 0.0 4.1 4 1 1 5 5 5 0 Tetratricopeptide repeat Ras PF00071.22 KKK23842.1 - 5.5e-43 146.4 0.3 2.6e-42 144.2 0.3 1.8 1 1 0 1 1 1 1 Ras family Roc PF08477.13 KKK23842.1 - 3.4e-18 66.0 0.0 6.4e-18 65.1 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKK23842.1 - 4.9e-05 22.9 0.2 0.00034 20.1 0.2 1.9 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KKK23842.1 - 0.038 13.4 0.0 0.05 12.9 0.0 1.3 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_16 PF13191.6 KKK23842.1 - 0.057 13.8 0.0 0.079 13.3 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain BPL_LplA_LipB PF03099.19 KKK23843.1 - 0.00012 22.0 0.0 0.00021 21.2 0.0 1.4 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Acetyltransf_1 PF00583.25 KKK23845.1 - 0.0006 20.0 0.2 0.0012 19.1 0.2 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KKK23845.1 - 0.0047 16.9 0.0 0.0093 15.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KKK23845.1 - 0.037 14.5 0.0 0.069 13.6 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KKK23845.1 - 0.045 13.8 0.2 0.13 12.4 0.1 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain PanZ PF12568.8 KKK23845.1 - 0.91 9.3 4.4 5.6 6.7 4.4 2.1 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ DAO PF01266.24 KKK23846.1 - 1.9e-30 106.6 0.2 3.6e-30 105.7 0.2 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KKK23846.1 - 6.1e-05 23.5 0.0 0.0017 18.8 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KKK23846.1 - 6.2e-05 23.1 0.1 0.00015 21.9 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KKK23846.1 - 8.6e-05 21.9 0.0 0.00038 19.8 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 KKK23846.1 - 0.00013 22.3 0.0 0.00024 21.5 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding FAD_binding_2 PF00890.24 KKK23846.1 - 0.0012 18.0 0.1 0.0027 16.9 0.0 1.5 2 0 0 2 2 2 1 FAD binding domain AlaDh_PNT_C PF01262.21 KKK23846.1 - 0.0029 17.0 0.0 0.0045 16.3 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ApbA PF02558.16 KKK23846.1 - 0.0081 15.8 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA FAD_binding_3 PF01494.19 KKK23846.1 - 0.014 14.6 0.0 0.025 13.8 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain 3HCDH_N PF02737.18 KKK23846.1 - 0.017 15.0 0.0 0.025 14.5 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 KKK23846.1 - 0.057 13.5 0.0 0.095 12.8 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase GIDA PF01134.22 KKK23846.1 - 0.11 11.6 0.1 0.15 11.1 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A UDPG_MGDP_dh_N PF03721.14 KKK23846.1 - 0.13 11.8 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Glu_dehyd_C PF16912.5 KKK23846.1 - 0.14 11.6 0.0 0.27 10.7 0.0 1.4 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus Sacchrp_dh_NADP PF03435.18 KKK23846.1 - 0.21 11.9 0.0 0.38 11.0 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain FAD_binding_3 PF01494.19 KKK23847.1 - 2.7e-05 23.6 0.0 3.8e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KKK23847.1 - 4.5e-05 23.2 0.1 6.8e-05 22.6 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KKK23847.1 - 6.3e-05 23.1 0.0 0.00015 21.9 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KKK23847.1 - 0.00016 21.0 0.0 0.0068 15.7 0.0 2.0 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KKK23847.1 - 0.00024 20.1 0.0 0.002 17.0 0.0 1.9 2 0 0 2 2 2 1 Tryptophan halogenase NAD_binding_9 PF13454.6 KKK23847.1 - 0.00037 20.5 0.1 0.0032 17.5 0.1 2.0 2 0 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.17 KKK23847.1 - 0.0083 15.4 0.0 0.012 14.9 0.0 1.1 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 KKK23847.1 - 0.039 13.0 0.0 0.061 12.4 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain MCRA PF06100.11 KKK23847.1 - 0.087 11.6 0.0 0.11 11.2 0.0 1.1 1 0 0 1 1 1 0 MCRA family Pyr_redox PF00070.27 KKK23847.1 - 0.2 12.2 0.0 0.98 10.0 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KKK23847.1 - 0.96 8.5 2.2 1.5 7.8 2.2 1.5 1 1 0 1 1 1 0 Glucose inhibited division protein A FAD_binding_3 PF01494.19 KKK23848.1 - 0.00039 19.8 0.0 0.00045 19.6 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pec_lyase_C PF00544.19 KKK23849.1 - 3.1e-47 160.9 8.9 4.4e-47 160.4 8.9 1.1 1 0 0 1 1 1 1 Pectate lyase Glyco_hydro_18 PF00704.28 KKK23850.1 - 3.4e-10 40.1 0.0 5.2e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 UBA PF00627.31 KKK23851.1 - 0.017 15.0 0.0 0.061 13.2 0.0 2.0 1 0 0 1 1 1 0 UBA/TS-N domain DnaJ PF00226.31 KKK23851.1 - 0.045 13.9 2.1 0.12 12.6 0.0 2.3 2 0 0 2 2 2 0 DnaJ domain TPR_12 PF13424.6 KKK23851.1 - 0.053 13.8 0.2 0.15 12.4 0.2 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TetR_C_1 PF02909.17 KKK23851.1 - 0.086 12.7 0.0 0.3 10.9 0.0 1.9 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain TPR_2 PF07719.17 KKK23851.1 - 0.12 12.5 5.4 0.04 14.0 1.2 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat GCD14 PF08704.10 KKK23852.1 - 7.4e-54 183.0 0.0 1.6e-53 181.9 0.0 1.6 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit tRNA-synt_1e PF01406.19 KKK23853.1 - 1.6e-115 385.7 0.0 2.6e-115 385.0 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 KKK23853.1 - 3.9e-06 25.9 0.6 0.035 12.9 0.2 3.0 3 0 0 3 3 3 2 tRNA synthetases class I (M) 40S_SA_C PF16122.5 KKK23853.1 - 2.9 9.3 8.2 15 7.0 8.2 2.3 1 0 0 1 1 1 0 40S ribosomal protein SA C-terminus NMO PF03060.15 KKK23854.1 - 5.5e-54 183.8 0.6 4.6e-33 115.0 0.2 2.0 1 1 1 2 2 2 2 Nitronate monooxygenase IMPDH PF00478.25 KKK23854.1 - 6.9e-15 54.9 0.0 1.8e-07 30.5 0.0 2.1 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 KKK23854.1 - 0.0013 17.9 0.4 0.0023 17.0 0.4 1.4 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 KKK23854.1 - 0.043 13.0 0.5 0.12 11.5 0.2 1.8 1 1 1 2 2 2 0 Conserved region in glutamate synthase Hydrophobin PF01185.18 KKK23855.1 - 2.4e-08 34.5 6.7 3.3e-08 34.1 6.7 1.2 1 0 0 1 1 1 1 Fungal hydrophobin DUF1688 PF07958.11 KKK23856.1 - 8.7e-180 597.9 0.0 9.9e-180 597.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) DDT PF02791.17 KKK23856.1 - 0.15 12.4 0.1 0.46 10.8 0.0 1.8 2 0 0 2 2 2 0 DDT domain Gtr1_RagA PF04670.12 KKK23857.1 - 1.1e-93 312.9 0.3 1.3e-93 312.6 0.3 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Roc PF08477.13 KKK23857.1 - 8.2e-09 35.7 0.0 1.5e-08 34.8 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKK23857.1 - 5.3e-08 32.5 0.0 7.7e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 KKK23857.1 - 7.7e-08 32.1 0.0 1.2e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 KKK23857.1 - 2.8e-07 30.6 0.0 7.2e-07 29.3 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase G-alpha PF00503.20 KKK23857.1 - 0.0014 17.9 2.2 0.52 9.4 0.0 2.4 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1_Xtn PF16897.5 KKK23857.1 - 0.0061 16.6 0.1 0.013 15.5 0.1 1.5 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain AAA_29 PF13555.6 KKK23857.1 - 0.0076 16.0 0.4 0.045 13.5 0.2 2.2 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF815 PF05673.13 KKK23857.1 - 0.0096 15.1 0.1 0.021 14.0 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) ABC_tran PF00005.27 KKK23857.1 - 0.016 15.7 0.0 0.037 14.6 0.0 1.5 1 0 0 1 1 1 0 ABC transporter RsgA_GTPase PF03193.16 KKK23857.1 - 0.074 13.0 0.2 0.44 10.4 0.0 2.3 3 0 0 3 3 3 0 RsgA GTPase AAA_7 PF12775.7 KKK23857.1 - 0.088 12.3 0.1 0.24 10.9 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region AIG1 PF04548.16 KKK23857.1 - 0.14 11.5 0.2 0.48 9.7 0.0 2.0 2 0 0 2 2 2 0 AIG1 family QCR10 PF09796.9 KKK23858.1 - 1.9e-26 91.9 0.5 2.5e-26 91.5 0.5 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) ETC_C1_NDUFA5 PF04716.14 KKK23859.1 - 7.6e-28 96.1 9.7 7.1e-27 93.0 0.0 3.1 4 0 0 4 4 4 2 ETC complex I subunit conserved region Thioredoxin PF00085.20 KKK23860.1 - 4e-47 158.5 0.1 1.8e-24 85.7 0.0 4.4 3 1 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.6 KKK23860.1 - 1.8e-09 37.8 0.0 0.046 13.6 0.0 5.0 3 1 2 5 5 5 2 Thioredoxin-like domain Thioredoxin_2 PF13098.6 KKK23860.1 - 2.5e-07 31.1 0.7 0.1 13.0 0.0 3.9 3 1 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KKK23860.1 - 0.00013 22.3 0.1 0.21 12.0 0.0 4.0 3 2 0 3 3 3 1 Thioredoxin-like AhpC-TSA PF00578.21 KKK23860.1 - 0.0031 17.4 1.2 0.071 13.0 0.1 3.0 3 0 0 3 3 3 1 AhpC/TSA family TraF PF13728.6 KKK23860.1 - 0.0045 16.8 4.8 0.076 12.8 0.2 3.6 3 1 1 4 4 4 1 F plasmid transfer operon protein HyaE PF07449.11 KKK23860.1 - 0.0054 16.7 0.0 2.2 8.3 0.0 3.2 4 0 0 4 4 4 1 Hydrogenase-1 expression protein HyaE Thioredoxin_7 PF13899.6 KKK23860.1 - 0.013 15.7 1.0 0.13 12.5 0.1 2.8 2 0 0 2 2 2 0 Thioredoxin-like Thioredoxin_3 PF13192.6 KKK23860.1 - 0.014 15.5 0.2 1.5 8.9 0.0 2.8 3 0 0 3 3 3 0 Thioredoxin domain OST3_OST6 PF04756.13 KKK23860.1 - 0.049 13.0 0.1 10 5.4 0.0 2.4 2 0 0 2 2 2 0 OST3 / OST6 family, transporter family DUF3557 PF12078.8 KKK23860.1 - 0.14 12.1 0.0 0.31 11.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3557) Coatomer_WDAD PF04053.14 KKK23861.1 - 5.9e-159 529.9 0.0 2e-156 521.5 0.0 2.7 2 1 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.32 KKK23861.1 - 6.4e-38 128.1 8.0 2.2e-06 28.3 0.0 8.4 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKK23861.1 - 1.1e-07 32.0 0.0 2.3 8.6 0.0 6.0 3 2 2 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KKK23861.1 - 0.0002 20.1 1.9 0.17 10.5 0.0 4.1 1 1 4 5 5 5 2 Nucleoporin Nup120/160 BBS2_Mid PF14783.6 KKK23861.1 - 0.064 13.3 0.0 11 6.1 0.0 3.4 2 2 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region MetallophosC PF16370.5 KKK23861.1 - 0.085 13.1 0.0 0.27 11.5 0.0 1.7 1 1 0 1 1 1 0 C terminal of Calcineurin-like phosphoesterase C2 PF00168.30 KKK23862.1 - 0.11 12.8 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 C2 domain Mlf1IP PF10248.9 KKK23862.1 - 5.4 6.9 6.5 1.6 8.7 0.3 2.1 2 0 0 2 2 2 0 Myelodysplasia-myeloid leukemia factor 1-interacting protein ZZ PF00569.17 KKK23863.1 - 6.1e-11 42.0 6.2 9.9e-11 41.3 6.2 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type SWIRM PF04433.17 KKK23863.1 - 2.3e-10 40.7 0.0 7.1e-10 39.1 0.0 1.8 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-binding PF00249.31 KKK23863.1 - 2.7e-10 40.3 0.0 8.3e-10 38.7 0.0 1.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain Asp PF00026.23 KKK23865.1 - 4.9e-96 321.9 0.2 2.8e-62 211.0 0.2 2.3 1 1 1 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 KKK23865.1 - 2.3e-16 60.5 1.6 7.5e-14 52.4 1.6 2.7 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KKK23865.1 - 2.5e-05 24.8 0.1 0.35 11.5 0.0 3.3 2 2 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.6 KKK23865.1 - 0.0003 20.6 0.0 0.0023 17.7 0.0 2.1 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.6 KKK23865.1 - 0.0022 18.5 0.0 5.1 7.7 0.0 3.1 3 1 0 3 3 3 2 gag-polyprotein putative aspartyl protease MARVEL PF01284.23 KKK23866.1 - 0.0014 18.7 9.5 0.0017 18.4 9.5 1.2 1 0 0 1 1 1 1 Membrane-associating domain PhoLip_ATPase_C PF16212.5 KKK23866.1 - 0.051 13.3 5.7 0.065 13.0 5.7 1.1 1 0 0 1 1 1 0 Phospholipid-translocating P-type ATPase C-terminal NIF PF03031.18 KKK23867.1 - 6e-26 91.1 0.1 1.9e-25 89.5 0.0 1.8 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase BRCT PF00533.26 KKK23867.1 - 1.8e-07 31.4 0.0 4.5e-07 30.2 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 KKK23867.1 - 0.00018 21.8 0.1 0.0017 18.7 0.0 2.4 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain PTCB-BRCT PF12738.7 KKK23867.1 - 0.0019 18.1 0.2 0.0044 16.9 0.2 1.6 1 0 0 1 1 1 1 twin BRCT domain BRCT_3 PF18428.1 KKK23867.1 - 0.0033 17.5 0.0 0.011 15.8 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain RTT107_BRCT_5 PF16770.5 KKK23867.1 - 0.0042 16.9 0.0 0.011 15.6 0.0 1.7 1 0 0 1 1 1 1 Regulator of Ty1 transposition protein 107 BRCT domain AAA PF00004.29 KKK23868.1 - 2e-46 157.7 0.5 6.6e-46 156.0 0.0 2.1 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 KKK23868.1 - 1.2e-10 41.2 0.1 7.6e-10 38.6 0.0 2.2 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_2 PF07724.14 KKK23868.1 - 9.5e-09 35.6 0.0 2e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 KKK23868.1 - 1e-08 35.2 0.5 3.5e-08 33.6 0.1 2.1 2 2 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KKK23868.1 - 1e-07 32.5 0.4 2.6e-05 24.6 0.0 2.8 2 1 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 KKK23868.1 - 2.7e-05 24.4 1.2 0.0051 17.1 0.1 2.7 1 1 1 2 2 2 1 AAA domain DUF815 PF05673.13 KKK23868.1 - 6.8e-05 22.1 0.0 0.00014 21.2 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_14 PF13173.6 KKK23868.1 - 0.00015 21.8 0.0 0.00057 19.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_lid_3 PF17862.1 KKK23868.1 - 0.0002 21.1 0.0 0.00045 20.0 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain TsaE PF02367.17 KKK23868.1 - 0.00027 20.9 0.0 0.02 14.9 0.0 2.3 1 1 1 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE RuvB_N PF05496.12 KKK23868.1 - 0.0003 20.6 0.0 0.00087 19.1 0.0 1.8 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_7 PF12775.7 KKK23868.1 - 0.00049 19.6 0.0 0.0068 15.9 0.1 2.5 2 1 0 2 2 2 1 P-loop containing dynein motor region AAA_18 PF13238.6 KKK23868.1 - 0.0012 19.3 0.0 0.0037 17.8 0.0 1.8 2 0 0 2 2 1 1 AAA domain NTPase_1 PF03266.15 KKK23868.1 - 0.0013 18.7 0.0 0.0049 16.8 0.0 1.9 2 0 0 2 2 2 1 NTPase RNA_helicase PF00910.22 KKK23868.1 - 0.0014 19.0 0.0 0.0031 17.9 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_33 PF13671.6 KKK23868.1 - 0.002 18.3 0.0 0.0043 17.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 KKK23868.1 - 0.0048 16.8 0.3 0.11 12.4 0.0 2.8 3 0 0 3 3 3 1 NACHT domain AAA_3 PF07726.11 KKK23868.1 - 0.0049 16.7 0.0 0.014 15.2 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.13 KKK23868.1 - 0.0056 15.9 0.0 0.011 15.0 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_28 PF13521.6 KKK23868.1 - 0.0077 16.5 0.0 0.018 15.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 KKK23868.1 - 0.0078 15.6 0.0 0.018 14.4 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 KKK23868.1 - 0.0085 15.8 0.1 0.23 11.1 0.0 2.5 2 1 0 2 2 2 1 Sigma-54 interaction domain TniB PF05621.11 KKK23868.1 - 0.011 15.2 0.0 0.54 9.6 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein AAA_30 PF13604.6 KKK23868.1 - 0.012 15.4 0.8 0.03 14.0 0.1 2.1 2 1 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KKK23868.1 - 0.012 15.4 0.0 0.024 14.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KKK23868.1 - 0.018 14.8 0.1 0.051 13.3 0.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_11 PF13086.6 KKK23868.1 - 0.042 13.6 0.1 0.13 12.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 KKK23868.1 - 0.061 13.2 1.6 0.38 10.6 0.1 2.6 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea Bac_DnaA PF00308.18 KKK23868.1 - 0.065 13.1 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Bacterial dnaA protein AAA_23 PF13476.6 KKK23868.1 - 0.091 13.3 0.2 2.7 8.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KKK23868.1 - 0.093 12.0 0.1 0.24 10.7 0.0 1.7 2 0 0 2 2 1 0 Zeta toxin ATPase PF06745.13 KKK23868.1 - 0.11 11.8 0.4 0.56 9.5 0.0 2.2 3 0 0 3 3 2 0 KaiC AAA_25 PF13481.6 KKK23868.1 - 0.13 11.8 1.7 0.22 11.1 0.1 2.1 2 1 1 3 3 3 0 AAA domain AAA_29 PF13555.6 KKK23868.1 - 0.13 12.0 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_19 PF13245.6 KKK23868.1 - 0.13 12.5 0.1 0.4 11.0 0.1 1.8 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KKK23868.1 - 0.14 12.6 0.1 0.56 10.7 0.0 2.1 2 0 0 2 2 2 0 ABC transporter Viral_Hsp90 PF03225.14 KKK23868.1 - 0.15 10.5 0.0 0.24 9.8 0.0 1.2 1 0 0 1 1 1 0 Viral heat shock protein Hsp90 homologue Parvo_NS1 PF01057.17 KKK23868.1 - 0.2 10.7 0.0 0.37 9.8 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 F-box-like PF12937.7 KKK23869.1 - 1.5e-12 47.1 0.6 1.5e-12 47.1 0.6 2.3 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 KKK23869.1 - 2.1e-12 47.0 11.7 0.35 11.4 0.1 8.0 4 2 4 9 9 9 5 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KKK23869.1 - 3.2e-11 42.3 19.4 1.3 9.3 0.0 11.2 12 0 0 12 12 12 3 Leucine Rich repeat F-box PF00646.33 KKK23869.1 - 2.7e-05 23.9 0.2 2.7e-05 23.9 0.2 2.5 3 0 0 3 3 3 1 F-box domain DUF1699 PF08004.11 KKK23869.1 - 0.00031 20.4 1.1 0.055 13.1 0.0 3.9 3 2 0 4 4 4 1 Protein of unknown function (DUF1699) LRR_8 PF13855.6 KKK23869.1 - 0.076 12.8 9.3 2 8.3 0.0 5.7 7 2 0 7 7 7 0 Leucine rich repeat Preseq_ALAS PF09029.10 KKK23869.1 - 0.89 10.0 5.2 0.75 10.3 0.1 3.2 3 1 1 4 4 4 0 5-aminolevulinate synthase presequence Peptidase_M28 PF04389.17 KKK23870.1 - 2.7e-35 121.9 0.0 4.5e-35 121.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 KKK23870.1 - 0.017 14.8 0.0 0.03 14.0 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 ATP-synt_8 PF00895.20 KKK23870.1 - 0.019 15.4 0.2 0.019 15.4 0.2 3.9 4 0 0 4 4 4 0 ATP synthase protein 8 CENP-B_dimeris PF09026.10 KKK23870.1 - 0.32 11.4 9.0 0.72 10.3 9.0 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Pox_Ag35 PF03286.14 KKK23870.1 - 0.43 10.4 2.7 0.72 9.6 2.7 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein FAM176 PF14851.6 KKK23870.1 - 1.4 8.5 3.9 3.1 7.5 3.9 1.4 1 0 0 1 1 1 0 FAM176 family SLAIN PF15301.6 KKK23870.1 - 2 7.6 4.7 3.1 7.0 4.7 1.2 1 0 0 1 1 1 0 SLAIN motif-containing family DUF2457 PF10446.9 KKK23870.1 - 2.4 7.2 10.1 3.6 6.6 10.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DNA_pol_phi PF04931.13 KKK23870.1 - 8.4 4.4 9.2 12 3.8 9.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi TauD PF02668.16 KKK23872.1 - 4.9e-19 69.2 0.8 7.1e-12 45.7 0.5 2.2 1 1 1 2 2 2 2 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 KKK23872.1 - 0.06 12.5 0.4 0.1 11.7 0.4 1.2 1 0 0 1 1 1 0 CsiD DUF3841 PF12952.7 KKK23872.1 - 0.14 11.9 0.1 0.25 11.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3841) TonB_N PF16031.5 KKK23873.1 - 4.2 7.9 9.9 0.041 14.4 1.6 1.9 2 0 0 2 2 2 0 TonB polyproline region Zn_clus PF00172.18 KKK23873.1 - 6.3 7.0 12.2 0.81 9.9 7.6 1.9 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.25 KKK23875.1 - 4.8e-38 131.0 0.0 6.9e-38 130.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK23875.1 - 6.8e-27 94.4 0.0 9.7e-27 93.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KKK23875.1 - 0.077 12.9 0.1 7.1 6.5 0.0 2.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family Spt5_N PF11942.8 KKK23875.1 - 0.35 11.9 3.9 1.6 9.8 0.3 2.7 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Med10 PF09748.9 KKK23876.1 - 4.2e-41 139.7 0.1 5e-41 139.5 0.1 1.1 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex DUF3877 PF12993.7 KKK23876.1 - 0.05 13.5 0.0 0.07 13.0 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function, E. rectale Gene description (DUF3877) Amidase PF01425.21 KKK23877.1 - 3.4e-84 283.4 0.0 5.2e-84 282.8 0.0 1.3 1 0 0 1 1 1 1 Amidase Pkinase PF00069.25 KKK23878.1 - 1.3e-09 37.9 0.0 5.2e-09 35.8 0.0 1.9 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK23878.1 - 2.4e-08 33.6 0.0 1.3e-07 31.2 0.0 2.1 2 1 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 KKK23878.1 - 0.066 12.5 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KKK23878.1 - 0.07 13.0 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family CN_hydrolase PF00795.22 KKK23879.1 - 5.4e-34 117.7 0.0 7.7e-34 117.2 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Band_7_C PF16200.5 KKK23879.1 - 0.042 13.9 0.0 0.15 12.1 0.0 1.8 2 0 0 2 2 2 0 C-terminal region of band_7 Mpv17_PMP22 PF04117.12 KKK23880.1 - 3.2e-19 68.9 0.1 3.2e-19 68.9 0.1 1.9 2 0 0 2 2 2 1 Mpv17 / PMP22 family Trs65 PF12735.7 KKK23881.1 - 8.8e-76 255.3 0.0 1.1e-75 254.9 0.0 1.1 1 0 0 1 1 1 1 TRAPP trafficking subunit Trs65 FF PF01846.19 KKK23882.1 - 2.3e-59 197.4 17.0 7.3e-16 58.1 0.5 7.2 6 1 0 6 6 6 6 FF domain WW PF00397.26 KKK23882.1 - 7.6e-17 61.1 13.1 6.4e-08 32.5 0.4 2.7 2 0 0 2 2 2 2 WW domain RhoGAP-FF1 PF16512.5 KKK23882.1 - 0.0015 19.1 11.2 2.6 8.8 0.3 4.7 3 1 1 4 4 4 3 p190-A and -B Rho GAPs FF domain HycH PF07450.11 KKK23882.1 - 0.13 12.7 0.7 0.34 11.3 0.7 1.8 1 0 0 1 1 1 0 Formate hydrogenlyase maturation protein HycH EMP24_GP25L PF01105.24 KKK23882.1 - 0.21 11.5 1.3 0.55 10.1 1.3 1.7 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Glyco_hyd_101C PF17451.2 KKK23882.1 - 0.37 11.1 7.0 5.9 7.2 2.4 2.7 1 1 1 2 2 2 0 Glycosyl hydrolase 101 beta sandwich domain DUF3808 PF10300.9 KKK23883.1 - 1.3e-161 538.6 0.2 1.3e-161 538.6 0.2 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3808) DSS1_SEM1 PF05160.13 KKK23884.1 - 1.1e-24 86.2 15.2 1.7e-24 85.6 15.2 1.3 1 0 0 1 1 1 1 DSS1/SEM1 family PGK PF00162.19 KKK23885.1 - 2.5e-138 461.1 4.8 9.7e-138 459.2 4.8 1.7 1 1 0 1 1 1 1 Phosphoglycerate kinase SBP_bac_8 PF13416.6 KKK23885.1 - 0.0032 17.3 1.3 0.0058 16.5 0.6 1.7 2 0 0 2 2 2 1 Bacterial extracellular solute-binding protein TPT PF03151.16 KKK23886.1 - 2.8e-23 82.7 23.5 3.2e-23 82.5 23.5 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 KKK23886.1 - 5.9e-07 29.0 21.6 8e-07 28.5 21.6 1.2 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 KKK23886.1 - 0.0011 19.1 12.5 0.0011 19.1 12.5 2.3 2 0 0 2 2 2 1 EamA-like transporter family MARVEL PF01284.23 KKK23887.1 - 7.4e-31 107.1 11.8 8.4e-31 106.9 11.8 1.0 1 0 0 1 1 1 1 Membrane-associating domain Gly_transf_sug PF04488.15 KKK23888.1 - 8e-14 52.1 0.1 1.3e-13 51.4 0.1 1.3 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.7 KKK23888.1 - 1.6 7.9 3.8 19 4.4 0.9 2.1 2 0 0 2 2 2 0 TcdA/TcdB catalytic glycosyltransferase domain AMP-binding_C PF13193.6 KKK23901.1 - 7.1e-15 55.7 0.2 9.6e-15 55.3 0.2 1.2 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain MFS_1 PF07690.16 KKK23902.1 - 2e-45 155.3 42.6 2e-45 155.3 42.6 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KKK23902.1 - 5.6e-09 35.4 23.8 1.8e-08 33.7 23.8 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_4 PF06779.14 KKK23902.1 - 8.8e-07 28.5 8.9 8.8e-07 28.5 8.9 2.5 3 0 0 3 3 3 1 Uncharacterised MFS-type transporter YbfB TRI12 PF06609.13 KKK23902.1 - 4.4e-06 25.4 4.1 7e-06 24.7 4.1 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 KKK23902.1 - 1.6 7.0 17.3 0.073 11.4 6.2 3.4 2 1 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family DUF3712 PF12505.8 KKK23903.1 - 1.5e-29 102.8 0.2 5.9e-29 100.9 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3712) DUF1765 PF08578.10 KKK23903.1 - 0.22 12.0 1.2 24 5.4 0.2 3.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1765) vATP-synt_AC39 PF01992.16 KKK23903.1 - 0.27 10.7 1.0 1.3 8.5 0.4 2.3 2 1 0 2 2 2 0 ATP synthase (C/AC39) subunit Zn_clus PF00172.18 KKK23905.1 - 2.9e-08 33.7 10.6 7.5e-08 32.4 10.6 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2 PF00096.26 KKK23905.1 - 0.0099 16.3 1.5 0.039 14.4 1.5 2.2 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KKK23905.1 - 0.13 13.2 1.7 0.71 10.9 1.7 2.4 1 0 0 1 1 1 0 C2H2-type zinc finger Opy2 PF09463.10 KKK23905.1 - 4.5 7.7 8.4 15 6.0 8.3 2.0 1 1 0 1 1 1 0 Opy2 protein Tri3 PF07428.11 KKK23906.1 - 2.4e-07 30.0 0.0 0.0014 17.6 0.0 2.1 2 0 0 2 2 2 2 15-O-acetyltransferase Tri3 Condensation PF00668.20 KKK23906.1 - 0.00033 19.4 0.0 0.16 10.6 0.0 2.1 2 0 0 2 2 2 2 Condensation domain ParG PF09274.10 KKK23906.1 - 0.19 11.9 0.0 0.41 10.8 0.0 1.5 1 0 0 1 1 1 0 ParG RTA1 PF04479.13 KKK23908.1 - 8.4e-68 228.0 7.5 9.6e-68 227.9 7.5 1.0 1 0 0 1 1 1 1 RTA1 like protein Ank_2 PF12796.7 KKK23909.1 - 7e-37 125.9 5.9 1.2e-13 51.4 0.0 8.2 6 2 0 7 7 7 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KKK23909.1 - 3.2e-29 100.9 13.8 1.3e-06 28.8 0.0 10.1 7 3 5 12 12 12 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 KKK23909.1 - 2e-28 98.1 6.8 0.0012 19.1 0.1 9.2 9 0 0 9 9 9 5 Ankyrin repeats (many copies) Ank PF00023.30 KKK23909.1 - 1.9e-22 78.6 14.1 0.00091 19.6 0.0 10.1 10 0 0 10 10 10 5 Ankyrin repeat Ank_3 PF13606.6 KKK23909.1 - 3.8e-22 76.0 7.9 0.0049 17.3 0.0 10.7 12 0 0 12 12 12 3 Ankyrin repeat 2OG-FeII_Oxy_3 PF13640.6 KKK23910.1 - 4.2e-07 30.8 0.0 7.8e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PLA2_B PF01735.18 KKK23911.1 - 1.5e-200 666.8 2.4 1.8e-200 666.5 2.4 1.1 1 0 0 1 1 1 1 Lysophospholipase catalytic domain MMS19_C PF12460.8 KKK23913.1 - 6.1e-16 58.5 1.5 8.7e-16 58.0 1.5 1.2 1 0 0 1 1 1 1 RNAPII transcription regulator C-terminal HEAT_2 PF13646.6 KKK23913.1 - 0.00022 21.5 1.8 0.28 11.6 0.3 2.5 2 1 0 2 2 2 2 HEAT repeats HEAT_EZ PF13513.6 KKK23913.1 - 0.0017 18.9 3.2 2.2 8.9 0.4 3.4 3 1 0 3 3 3 2 HEAT-like repeat HEAT PF02985.22 KKK23913.1 - 0.0031 17.6 4.5 0.5 10.8 0.1 2.9 3 0 0 3 3 3 2 HEAT repeat CAF1A PF12253.8 KKK23915.1 - 7.3e-21 74.1 5.8 7.3e-21 74.1 5.8 3.8 2 1 0 2 2 2 1 Chromatin assembly factor 1 subunit A CAF-1_p150 PF11600.8 KKK23915.1 - 7.2e-07 29.0 54.9 1.8e-06 27.8 54.9 1.6 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal TFIIF_alpha PF05793.12 KKK23915.1 - 0.00049 18.8 26.4 0.00049 18.8 26.4 2.3 2 0 0 2 2 2 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF262 PF03235.14 KKK23915.1 - 0.057 13.6 2.7 0.12 12.5 2.7 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF262 SprA-related PF12118.8 KKK23915.1 - 0.6 9.2 20.5 1 8.5 20.5 1.3 1 0 0 1 1 1 0 SprA-related family SLC12 PF03522.15 KKK23915.1 - 1 8.3 17.0 1.8 7.5 17.0 1.3 1 0 0 1 1 1 0 Solute carrier family 12 Raftlin PF15250.6 KKK23915.1 - 1.4 7.6 17.5 0.29 9.9 14.0 1.6 2 0 0 2 2 2 0 Raftlin Fungal_trans_2 PF11951.8 KKK23916.1 - 9.9e-92 307.7 0.0 1.3e-91 307.3 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK23916.1 - 1.4e-05 25.1 11.2 2.5e-05 24.3 11.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Njmu-R1 PF15053.6 KKK23916.1 - 0.14 11.2 0.5 5.7 5.9 0.0 2.1 2 0 0 2 2 2 0 Mjmu-R1-like protein family Peptidase_M48 PF01435.18 KKK23917.1 - 4.7e-35 121.2 0.0 8.8e-35 120.3 0.0 1.4 1 1 0 1 1 1 1 Peptidase family M48 Cpn60_TCP1 PF00118.24 KKK23918.1 - 4.6e-147 490.6 9.9 5.6e-147 490.3 9.9 1.1 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF2052 PF09747.9 KKK23918.1 - 0.0031 17.6 2.0 0.0054 16.9 2.0 1.3 1 0 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) Sigma70_ner PF04546.13 KKK23918.1 - 0.015 15.2 3.1 0.032 14.1 3.1 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region PPP4R2 PF09184.11 KKK23918.1 - 0.039 13.5 3.0 0.07 12.7 2.5 1.7 2 0 0 2 2 2 0 PPP4R2 Ribosomal_60s PF00428.19 KKK23918.1 - 0.06 13.9 11.3 0.098 13.3 10.0 2.0 2 0 0 2 2 1 0 60s Acidic ribosomal protein RPN2_C PF18004.1 KKK23918.1 - 0.07 13.0 4.2 0.15 11.9 4.2 1.5 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain PDZ_3 PF17815.1 KKK23918.1 - 0.14 12.1 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 PDZ domain RXT2_N PF08595.11 KKK23918.1 - 0.2 11.7 3.6 0.43 10.6 3.6 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal TetR_C_14 PF17754.1 KKK23918.1 - 0.27 11.2 3.9 0.77 9.7 1.3 2.4 2 0 0 2 2 2 0 MftR C-terminal domain NOA36 PF06524.12 KKK23918.1 - 0.79 9.0 10.9 1.3 8.3 10.9 1.2 1 0 0 1 1 1 0 NOA36 protein Nop14 PF04147.12 KKK23918.1 - 0.84 7.8 8.5 1.2 7.2 8.5 1.1 1 0 0 1 1 1 0 Nop14-like family FAM176 PF14851.6 KKK23918.1 - 0.88 9.2 6.6 1.8 8.2 6.6 1.4 1 0 0 1 1 1 0 FAM176 family Pox_Ag35 PF03286.14 KKK23918.1 - 0.92 9.3 7.4 0.28 11.0 4.0 1.8 2 0 0 2 2 2 0 Pox virus Ag35 surface protein DUF4746 PF15928.5 KKK23918.1 - 1.2 8.5 6.2 1.8 7.9 6.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) SURF2 PF05477.11 KKK23918.1 - 1.3 8.7 4.2 2.3 7.9 4.2 1.3 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) Nop53 PF07767.11 KKK23918.1 - 1.6 8.0 10.1 2.8 7.2 10.1 1.3 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) DNA_pol_phi PF04931.13 KKK23918.1 - 2.7 6.0 12.5 4.7 5.2 12.5 1.3 1 0 0 1 1 1 0 DNA polymerase phi SDA1 PF05285.12 KKK23918.1 - 5.8 6.2 11.5 2.4 7.5 7.7 1.9 2 0 0 2 2 2 0 SDA1 CENP-B_dimeris PF09026.10 KKK23918.1 - 7.7 7.0 15.3 18 5.8 15.3 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Polysacc_deac_1 PF01522.21 KKK23919.1 - 7.3e-20 71.1 0.0 1.9e-19 69.8 0.0 1.7 2 0 0 2 2 2 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 KKK23919.1 - 1.1e-07 31.4 0.0 1.4e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 Creatininase PF02633.14 KKK23919.1 - 5.4e-07 29.3 0.0 9.9e-07 28.5 0.0 1.4 1 0 0 1 1 1 1 Creatinine amidohydrolase Sec7 PF01369.20 KKK23919.1 - 0.13 11.9 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 Sec7 domain Nitroreductase PF00881.24 KKK23920.1 - 1.1e-16 61.3 0.0 1.3e-16 61.1 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family Ins_P5_2-kin PF06090.12 KKK23921.1 - 9.5e-46 156.7 0.0 1e-44 153.3 0.0 2.0 1 1 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase DUF4444 PF14563.6 KKK23921.1 - 0.025 14.2 0.0 0.05 13.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4444) Thiamine_BP PF01910.17 KKK23922.1 - 1.8e-11 43.8 0.1 5.4e-10 39.1 0.0 2.1 2 0 0 2 2 2 2 Thiamine-binding protein AAA PF00004.29 KKK23925.1 - 8.8e-38 129.7 0.0 3e-37 128.0 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KKK23925.1 - 1.3e-08 34.5 0.0 2.9e-08 33.4 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 KKK23925.1 - 1.6e-05 25.4 0.4 0.00042 20.7 0.1 3.1 2 2 0 2 2 2 1 AAA ATPase domain AAA_14 PF13173.6 KKK23925.1 - 3.4e-05 23.9 0.0 8.3e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 KKK23925.1 - 3.5e-05 23.6 0.0 7.3e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KKK23925.1 - 7.3e-05 22.8 0.2 0.00059 19.8 0.2 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 KKK23925.1 - 0.00022 21.8 0.0 0.0019 18.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_2 PF07724.14 KKK23925.1 - 0.00028 21.1 0.0 0.00062 19.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 KKK23925.1 - 0.00036 20.8 0.1 0.0053 17.0 0.1 2.5 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KKK23925.1 - 0.00059 20.0 0.0 0.0012 19.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KKK23925.1 - 0.00084 19.1 0.0 0.0018 18.0 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 KKK23925.1 - 0.0013 18.2 0.1 0.0024 17.3 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 KKK23925.1 - 0.002 18.5 0.0 0.0052 17.2 0.0 1.8 1 0 0 1 1 1 1 RNA helicase TniB PF05621.11 KKK23925.1 - 0.002 17.5 0.0 1.8 7.9 0.0 2.6 3 0 0 3 3 3 2 Bacterial TniB protein AAA_25 PF13481.6 KKK23925.1 - 0.0037 16.9 0.1 0.045 13.3 0.1 2.2 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KKK23925.1 - 0.0061 16.5 0.0 0.019 14.9 0.0 1.9 1 0 0 1 1 1 1 NACHT domain AAA_24 PF13479.6 KKK23925.1 - 0.0082 15.9 0.0 0.016 14.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 KKK23925.1 - 0.013 15.7 0.0 0.026 14.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 KKK23925.1 - 0.023 14.6 0.1 0.065 13.1 0.0 1.7 1 1 0 1 1 1 0 Rad17 P-loop domain Sigma54_activ_2 PF14532.6 KKK23925.1 - 0.025 14.7 0.0 0.055 13.6 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain Parvo_NS1 PF01057.17 KKK23925.1 - 0.027 13.6 0.0 0.044 12.9 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 ABC_tran PF00005.27 KKK23925.1 - 0.04 14.4 0.0 0.11 13.0 0.0 1.8 1 1 0 1 1 1 0 ABC transporter Sigma54_activat PF00158.26 KKK23925.1 - 0.045 13.4 0.0 0.093 12.4 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain DUF815 PF05673.13 KKK23925.1 - 0.073 12.2 0.0 0.16 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_7 PF12775.7 KKK23925.1 - 0.077 12.5 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region CPT PF07931.12 KKK23925.1 - 0.091 12.6 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein ATPase_2 PF01637.18 KKK23925.1 - 0.093 12.6 0.0 0.3 10.9 0.0 1.7 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea TsaE PF02367.17 KKK23925.1 - 0.11 12.4 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Viral_helicase1 PF01443.18 KKK23925.1 - 0.15 11.8 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_21 PF13304.6 KKK23925.1 - 0.16 11.7 0.1 15 5.3 0.0 2.7 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system TIP49 PF06068.13 KKK23925.1 - 0.17 11.0 0.1 0.44 9.7 0.0 1.7 2 0 0 2 2 2 0 TIP49 P-loop domain PigN PF04987.14 KKK23926.1 - 4.4e-167 556.5 40.3 4.4e-167 556.5 40.3 1.4 2 0 0 2 2 2 1 Phosphatidylinositolglycan class N (PIG-N) Csm1 PF12539.8 KKK23926.1 - 1.1e-31 109.3 0.8 2e-31 108.5 0.2 1.8 2 0 0 2 2 1 1 Chromosome segregation protein Csm1/Pcs1 Phosphodiest PF01663.22 KKK23926.1 - 3.2e-09 36.9 2.0 3.7e-07 30.1 2.0 2.5 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 KKK23926.1 - 2.1e-08 33.9 0.0 3.5e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Sulfatase MPS2 PF17060.5 KKK23926.1 - 0.06 12.6 3.8 0.1 11.9 3.8 1.3 1 0 0 1 1 1 0 Monopolar spindle protein 2 AAA_13 PF13166.6 KKK23926.1 - 0.092 11.4 4.6 0.15 10.6 4.6 1.3 1 0 0 1 1 1 0 AAA domain MscS_porin PF12795.7 KKK23926.1 - 0.11 12.0 16.8 0.23 11.0 16.8 1.4 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain DUF5094 PF17015.5 KKK23926.1 - 0.14 12.3 0.1 0.14 12.3 0.1 2.9 3 0 0 3 3 2 0 Domain of unknown function (DUF5094) Adeno_E4_34 PF04528.13 KKK23926.1 - 0.16 11.9 0.5 0.34 10.7 0.5 1.5 1 0 0 1 1 1 0 Adenovirus early E4 34 kDa protein conserved region DUF2968 PF11180.8 KKK23926.1 - 0.19 11.4 9.0 0.34 10.5 9.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) Stevor PF17410.2 KKK23926.1 - 0.19 11.2 1.2 0.48 9.9 1.2 1.6 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame APG6_N PF17675.1 KKK23926.1 - 0.2 12.2 11.0 0.44 11.1 11.0 1.6 1 0 0 1 1 1 0 Apg6 coiled-coil region TPR_MLP1_2 PF07926.12 KKK23926.1 - 0.29 11.2 11.1 1 9.4 11.1 2.0 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Spc7 PF08317.11 KKK23926.1 - 0.49 9.2 11.1 0.94 8.3 11.1 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein TRAF_BIRC3_bd PF16673.5 KKK23926.1 - 0.58 10.0 3.1 0.74 9.6 0.4 2.3 2 0 0 2 2 2 0 TNF receptor-associated factor BIRC3 binding domain DUF2203 PF09969.9 KKK23926.1 - 0.77 10.5 3.0 2.6 8.8 3.0 2.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) COG2 PF06148.11 KKK23926.1 - 1.3 9.1 3.0 3.1 7.9 3.0 1.6 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 ADIP PF11559.8 KKK23926.1 - 1.4 9.0 12.6 1.7 8.7 11.0 1.7 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF3138 PF11336.8 KKK23926.1 - 3.6 6.1 6.7 6.5 5.2 6.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Seryl_tRNA_N PF02403.22 KKK23926.1 - 4.4 7.6 5.8 11 6.3 5.8 1.7 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Fungal_trans PF04082.18 KKK23927.1 - 3.7e-34 118.0 0.0 8.9e-34 116.7 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK23927.1 - 0.0021 18.1 1.2 0.004 17.2 1.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cys_Met_Meta_PP PF01053.20 KKK23928.1 - 9.4e-143 475.3 0.0 1.3e-142 474.9 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Met_gamma_lyase PF06838.11 KKK23928.1 - 0.0021 16.6 0.0 0.0089 14.6 0.0 1.8 1 1 0 1 1 1 1 Methionine gamma-lyase SelA PF03841.13 KKK23928.1 - 0.0034 16.4 0.0 0.026 13.5 0.0 2.0 2 0 0 2 2 2 1 L-seryl-tRNA selenium transferase DegT_DnrJ_EryC1 PF01041.17 KKK23928.1 - 0.012 15.0 0.1 0.033 13.5 0.0 1.7 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 KKK23928.1 - 0.094 12.0 0.0 0.24 10.7 0.0 1.6 2 0 0 2 2 2 0 Beta-eliminating lyase SR-25 PF10500.9 KKK23928.1 - 5.1 6.6 13.2 8.3 5.9 13.2 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein ATP19 PF11022.8 KKK23929.1 - 1.9e-26 92.2 0.1 2.2e-26 92.0 0.1 1.0 1 0 0 1 1 1 1 ATP synthase subunit K COesterase PF00135.28 KKK23930.1 - 6.8e-83 279.3 0.0 1.9e-82 277.8 0.0 1.6 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KKK23930.1 - 0.00018 21.5 0.3 0.0018 18.1 0.3 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KKK23930.1 - 0.0028 17.2 0.0 0.0047 16.4 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family ACPS PF01648.20 KKK23931.1 - 1.2e-16 60.9 0.0 2.2e-16 60.0 0.0 1.5 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily PHP PF02811.19 KKK23931.1 - 1.9e-12 47.8 0.0 3e-12 47.2 0.0 1.3 1 0 0 1 1 1 1 PHP domain 4PPT_N PF17837.1 KKK23931.1 - 0.0045 17.1 1.0 0.016 15.3 0.4 2.2 2 1 0 2 2 2 1 4'-phosphopantetheinyl transferase N-terminal domain ELFV_dehydrog PF00208.21 KKK23932.1 - 1.8e-69 234.2 0.0 2.7e-69 233.6 0.0 1.3 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.12 KKK23932.1 - 1e-17 63.1 0.0 2.7e-13 48.5 0.0 2.2 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.18 KKK23932.1 - 0.0026 17.7 0.0 0.024 14.5 0.0 2.3 2 0 0 2 2 2 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain Ish1 PF10281.9 KKK23932.1 - 0.088 13.1 0.0 0.24 11.7 0.0 1.8 1 0 0 1 1 1 0 Putative stress-responsive nuclear envelope protein RIX1 PF08167.12 KKK23933.1 - 1.1e-59 201.4 3.0 2.7e-59 200.1 3.0 1.7 1 0 0 1 1 1 1 rRNA processing/ribosome biogenesis MMS19_N PF14500.6 KKK23933.1 - 0.035 13.7 0.7 0.37 10.3 0.0 2.8 3 0 0 3 3 3 0 Dos2-interacting transcription regulator of RNA-Pol-II Vitellogenin_N PF01347.22 KKK23933.1 - 0.18 10.1 0.5 0.45 8.8 0.0 1.8 3 0 0 3 3 3 0 Lipoprotein amino terminal region MBOAT_2 PF13813.6 KKK23935.1 - 7.7e-22 77.4 4.4 1.9e-21 76.1 4.4 1.7 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family TPR_14 PF13428.6 KKK23936.1 - 2.8e-10 40.1 25.4 0.36 11.8 0.1 8.9 10 0 0 10 10 8 4 Tetratricopeptide repeat TPR_2 PF07719.17 KKK23936.1 - 5.5e-10 38.6 9.4 0.024 14.7 0.1 6.7 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_1 PF00515.28 KKK23936.1 - 4e-07 29.6 7.3 0.0074 16.1 0.0 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 KKK23936.1 - 9.1e-07 28.6 8.6 3 8.3 0.0 6.4 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.6 KKK23936.1 - 0.0003 21.0 8.9 6.8 7.1 0.6 5.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 KKK23936.1 - 0.0042 17.7 22.5 1.1 10.0 0.0 7.0 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_19 PF14559.6 KKK23936.1 - 0.005 17.3 8.9 12 6.5 0.4 6.3 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.6 KKK23936.1 - 0.028 14.8 0.4 18 6.0 0.0 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.6 KKK23936.1 - 0.039 14.0 8.8 21 5.4 0.0 6.1 7 0 0 7 7 7 0 Tetratricopeptide repeat ABATE PF07336.11 KKK23936.1 - 0.052 14.2 2.5 0.2 12.3 0.3 3.1 3 0 0 3 3 3 0 Putative stress-induced transcription regulator DUF5444 PF17519.2 KKK23936.1 - 1.9 8.6 3.9 1.1 9.3 0.5 2.3 3 0 0 3 3 2 0 Family of unknown function (DUF5444) TPR_10 PF13374.6 KKK23936.1 - 4.3 7.3 10.6 2.5 8.1 0.0 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TRP PF06011.12 KKK23937.1 - 5.5e-171 569.0 27.5 6.9e-171 568.7 27.5 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 KKK23937.1 - 2.7e-41 141.2 0.8 4.6e-41 140.5 0.8 1.4 1 0 0 1 1 1 1 ML-like domain Rab5ip PF07019.12 KKK23937.1 - 0.051 14.2 10.4 0.057 14.0 1.1 3.4 3 0 0 3 3 3 0 Rab5-interacting protein (Rab5ip) Shisa PF13908.6 KKK23937.1 - 0.11 12.8 0.6 12 6.1 0.0 3.2 3 0 0 3 3 3 0 Wnt and FGF inhibitory regulator Ac76 PF05814.11 KKK23937.1 - 0.95 9.5 11.7 1.8 8.6 0.2 3.7 3 1 1 4 4 4 0 Orf76 (Ac76) DUF4834 PF16118.5 KKK23937.1 - 2.9 8.9 6.8 15 6.6 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) DUF3742 PF12553.8 KKK23937.1 - 6.1 7.0 14.4 0.91 9.7 0.4 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF3742) DEAD PF00270.29 KKK23938.1 - 7.6e-47 159.3 0.0 1.4e-46 158.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KKK23938.1 - 1.9e-23 82.9 0.0 1.3e-22 80.3 0.0 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 KKK23938.1 - 1.4e-17 63.7 0.2 2.6e-17 62.8 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Spore_coat_CotO PF14153.6 KKK23938.1 - 0.054 13.4 13.0 0.095 12.6 13.0 1.3 1 0 0 1 1 1 0 Spore coat protein CotO Pox_Ag35 PF03286.14 KKK23938.1 - 0.35 10.6 10.3 0.58 9.9 10.3 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Myc_N PF01056.18 KKK23938.1 - 0.64 9.9 8.0 1 9.2 8.0 1.2 1 0 0 1 1 1 0 Myc amino-terminal region Tub_N PF16322.5 KKK23938.1 - 1.5 9.2 15.7 2.5 8.5 15.7 1.3 1 0 0 1 1 1 0 Tubby N-terminal FAM176 PF14851.6 KKK23938.1 - 1.9 8.1 6.1 3.6 7.2 6.1 1.4 1 0 0 1 1 1 0 FAM176 family DUF4746 PF15928.5 KKK23938.1 - 3 7.2 12.8 5.6 6.3 12.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) NOA36 PF06524.12 KKK23938.1 - 3.2 7.0 11.8 35 3.6 10.8 2.1 2 0 0 2 2 2 0 NOA36 protein Vfa1 PF08432.10 KKK23938.1 - 3.3 8.0 12.2 5.9 7.2 12.2 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 RNA_pol_3_Rpc31 PF11705.8 KKK23938.1 - 7.1 6.8 17.7 14 5.9 17.7 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Glyco_hydro_47 PF01532.20 KKK23939.1 - 2.5e-158 527.7 0.0 2.8e-158 527.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Stb3 PF10330.9 KKK23940.1 - 8.9e-39 131.4 0.0 1.4e-38 130.8 0.0 1.3 1 0 0 1 1 1 1 Putative Sin3 binding protein NnrS PF05940.12 KKK23940.1 - 0.27 10.6 0.0 0.36 10.2 0.0 1.1 1 0 0 1 1 1 0 NnrS protein HNH_2 PF13391.6 KKK23942.1 - 2.6e-18 65.9 0.1 7.9e-18 64.4 0.1 1.9 2 0 0 2 2 2 1 HNH endonuclease Glu-tRNAGln PF02686.15 KKK23942.1 - 0.11 12.8 0.1 0.24 11.7 0.1 1.6 1 0 0 1 1 1 0 Glu-tRNAGln amidotransferase C subunit Cript PF10235.9 KKK23943.1 - 2.4e-26 92.1 8.9 2.4e-26 92.1 8.9 1.8 1 1 1 2 2 2 1 Microtubule-associated protein CRIPT DZR PF12773.7 KKK23943.1 - 0.0075 16.3 14.8 0.014 15.4 8.5 2.6 1 1 1 2 2 2 2 Double zinc ribbon CEBP_ZZ PF16366.5 KKK23943.1 - 0.018 15.2 4.7 0.018 15.2 4.7 1.8 2 0 0 2 2 2 0 Cytoplasmic polyadenylation element-binding protein ZZ domain zinc_ribbon_15 PF17032.5 KKK23943.1 - 0.019 15.7 11.2 0.076 13.8 7.7 2.7 2 1 0 2 2 2 0 zinc-ribbon family DUF2321 PF10083.9 KKK23943.1 - 0.066 12.8 2.2 0.1 12.3 2.2 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2321) zinc_ribbon_2 PF13240.6 KKK23943.1 - 0.14 12.0 12.3 3.2 7.6 3.1 3.4 3 0 0 3 3 3 0 zinc-ribbon domain Prok-RING_4 PF14447.6 KKK23943.1 - 0.34 10.8 10.1 0.34 10.8 1.7 3.1 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 zf-HYPF PF07503.12 KKK23943.1 - 0.49 10.2 10.2 1.1 9.1 5.5 2.3 2 0 0 2 2 2 0 HypF finger DUF2039 PF10217.9 KKK23943.1 - 1.2 9.5 17.1 0.54 10.6 11.2 2.3 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) zf-C3HC4_3 PF13920.6 KKK23943.1 - 3.7 7.5 14.9 62 3.6 10.2 3.0 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-ribbon_3 PF13248.6 KKK23943.1 - 6 6.4 9.2 3 7.4 0.2 3.2 3 0 0 3 3 3 0 zinc-ribbon domain DUF1272 PF06906.11 KKK23943.1 - 7 6.8 13.9 16 5.7 9.1 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1272) MRP-L46 PF11788.8 KKK23945.1 - 9.4e-39 132.8 1.6 1.6e-38 132.1 1.6 1.4 1 0 0 1 1 1 1 39S mitochondrial ribosomal protein L46 NUDIX PF00293.28 KKK23945.1 - 0.032 14.3 0.0 0.068 13.2 0.0 1.5 1 0 0 1 1 1 0 NUDIX domain CAF1 PF04857.20 KKK23946.1 - 2.4e-74 250.4 0.0 2.9e-74 250.1 0.0 1.1 1 0 0 1 1 1 1 CAF1 family ribonuclease DNA_pol_A_exo1 PF01612.20 KKK23946.1 - 0.068 12.9 0.0 0.4 10.4 0.0 2.1 2 0 0 2 2 2 0 3'-5' exonuclease AAA_23 PF13476.6 KKK23975.1 - 5.6e-37 128.2 2.6 5.6e-37 128.2 2.6 8.3 2 2 0 3 3 1 1 AAA domain SMC_N PF02463.19 KKK23975.1 - 1.6e-07 31.0 0.0 1.6e-07 31.0 0.0 3.4 2 1 0 2 2 1 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 KKK23975.1 - 3.2e-06 27.3 0.0 1.1e-05 25.6 0.0 1.9 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_15 PF13175.6 KKK23975.1 - 5.6e-05 23.0 9.3 5.6e-05 23.0 9.3 5.6 1 1 3 4 4 2 1 AAA ATPase domain KNOX2 PF03791.13 KKK23975.1 - 0.00017 21.0 0.0 0.0075 15.7 0.0 3.2 2 0 0 2 2 2 1 KNOX2 domain AAA_21 PF13304.6 KKK23975.1 - 0.00032 20.6 23.0 0.0022 17.8 0.0 4.3 3 2 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KKK23975.1 - 0.0007 19.3 0.0 0.0015 18.2 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 KKK23975.1 - 0.064 13.6 0.0 0.064 13.6 0.0 5.9 4 2 0 4 4 3 0 AAA ATPase domain AAA_13 PF13166.6 KKK23975.1 - 0.17 10.5 0.0 0.17 10.5 0.0 7.6 3 1 4 7 7 6 0 AAA domain Phage_tail_APC PF16778.5 KKK23975.1 - 0.56 10.1 3.3 32 4.5 0.1 4.0 3 0 0 3 3 3 0 Phage tail assembly chaperone protein DASH_Dam1 PF08653.10 KKK23975.1 - 6.2 6.7 10.2 10 6.0 0.4 5.5 5 0 0 5 5 5 0 DASH complex subunit Dam1 Glyco_transf_21 PF13506.6 KKK23976.1 - 3.5e-14 52.7 0.0 1.6e-06 27.7 0.0 3.8 1 1 1 2 2 2 2 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.6 KKK23976.1 - 8.6e-07 29.1 0.0 2e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KKK23976.1 - 0.0017 18.2 0.0 0.022 14.6 0.0 2.4 2 1 0 2 2 2 1 Glycosyl transferase family 2 Ank_2 PF12796.7 KKK23977.1 - 9.9e-13 48.5 0.2 4.6e-12 46.4 0.2 1.9 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 KKK23977.1 - 3.2e-09 36.8 1.4 2.1e-06 27.9 0.1 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 KKK23977.1 - 5.2e-09 35.6 0.5 5.1e-06 26.4 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 KKK23977.1 - 2e-06 28.2 0.8 1.7e-05 25.3 0.1 2.5 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 KKK23977.1 - 3.8e-06 27.1 0.7 6.3e-05 23.2 0.1 2.8 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Cupin_2 PF07883.11 KKK23978.1 - 9.9e-07 28.4 0.0 1.7e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.12 KKK23978.1 - 0.028 14.1 0.0 0.072 12.8 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF861) Peptidase_M54 PF07998.11 KKK23979.1 - 1.8e-06 28.1 0.1 3.5e-06 27.1 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M54 Zincin_1 PF06262.11 KKK23979.1 - 0.076 13.1 0.0 0.21 11.7 0.0 1.7 2 0 0 2 2 2 0 Zincin-like metallopeptidase SR-25 PF10500.9 KKK23979.1 - 0.16 11.6 13.5 0.22 11.1 13.5 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF1635 PF07795.11 KKK23979.1 - 1 9.2 4.2 1.4 8.7 4.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) SelP_N PF04592.14 KKK23979.1 - 3.6 6.9 13.0 5 6.4 13.0 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region RAP1 PF07218.11 KKK23979.1 - 7 4.8 5.2 8.5 4.5 5.2 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) SDP_N PF12278.8 KKK23979.1 - 8.8 6.5 7.7 12 6.0 7.7 1.2 1 0 0 1 1 1 0 Sex determination protein N terminal Abhydrolase_3 PF07859.13 KKK23980.1 - 1.5e-42 145.8 0.0 1.9e-42 145.5 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KKK23980.1 - 2.4e-10 39.9 1.8 8.9e-10 38.0 1.8 1.7 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_6 PF12697.7 KKK23980.1 - 3.9e-05 24.4 0.8 5.6e-05 23.8 0.8 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family zinc_ribbon_10 PF10058.9 KKK23981.1 - 1.3e-19 69.6 0.1 2.3e-19 68.9 0.1 1.4 1 0 0 1 1 1 1 Predicted integral membrane zinc-ribbon metal-binding protein Rubredoxin_2 PF18073.1 KKK23981.1 - 1.6 8.5 6.3 3.8 7.3 6.3 1.6 1 0 0 1 1 1 0 Rubredoxin metal binding domain Mit_KHE1 PF10173.9 KKK23983.1 - 1.2e-63 214.6 0.8 1.6e-63 214.2 0.8 1.1 1 0 0 1 1 1 1 Mitochondrial K+-H+ exchange-related DUF4478 PF14793.6 KKK23983.1 - 0.18 11.7 0.0 0.27 11.1 0.0 1.3 1 0 0 1 1 1 0 Pyrimidine/purine nucleotide 5'-monophosphate nucleosidases DUF588 PF04535.12 KKK23984.1 - 0.036 13.9 1.1 0.068 12.9 1.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF588) Cupin_2 PF07883.11 KKK23985.1 - 3.5e-08 33.0 0.7 5.5e-08 32.4 0.7 1.2 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 KKK23985.1 - 1.1e-06 28.3 0.1 1.9e-06 27.6 0.1 1.3 1 0 0 1 1 1 1 Cupin ARD PF03079.14 KKK23985.1 - 2.4e-05 24.6 0.0 3.5e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 ARD/ARD' family Cupin_6 PF12852.7 KKK23985.1 - 0.0022 17.7 0.0 0.0026 17.5 0.0 1.1 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.19 KKK23985.1 - 0.053 13.4 0.1 0.076 12.9 0.1 1.3 1 0 0 1 1 1 0 AraC-like ligand binding domain Cullin PF00888.22 KKK23986.1 - 2.2e-192 641.0 11.0 3e-192 640.5 11.0 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 KKK23986.1 - 1.7e-26 92.0 2.2 1.7e-26 92.0 2.2 2.7 4 0 0 4 4 4 1 Cullin protein neddylation domain DUF1906 PF08924.11 KKK23986.1 - 0.079 13.1 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1906) End3 PF12761.7 KKK23987.1 - 2.4e-68 230.2 1.2 3.4e-68 229.8 1.2 1.2 1 0 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 EF-hand_4 PF12763.7 KKK23987.1 - 2.6e-51 171.9 0.2 5.3e-48 161.3 0.1 2.3 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 KKK23987.1 - 5.2e-09 35.0 0.3 7.4e-08 31.4 0.3 2.6 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 KKK23987.1 - 3e-07 30.8 1.9 4.1e-06 27.2 0.1 3.2 3 1 1 4 4 4 1 EF-hand domain pair EF-hand_6 PF13405.6 KKK23987.1 - 6.1e-05 22.6 0.4 0.00036 20.2 0.2 2.4 2 0 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.6 KKK23987.1 - 0.00036 20.3 0.1 0.0027 17.5 0.1 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 KKK23987.1 - 0.0024 17.3 0.1 0.0076 15.7 0.1 1.9 1 0 0 1 1 1 1 EF hand Phlebovirus_NSM PF07246.11 KKK23987.1 - 0.65 9.3 3.3 1 8.7 3.3 1.3 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M Ribosomal_S8 PF00410.19 KKK23988.1 - 9.2e-22 77.3 0.0 1.2e-21 77.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 His_Phos_1 PF00300.22 KKK23989.1 - 3.9e-13 49.5 0.0 2.4e-07 30.6 0.0 2.3 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) Glyco_hydro_18 PF00704.28 KKK23992.1 - 2.3e-70 237.8 2.5 3.9e-70 237.1 2.5 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 KKK23992.1 - 2.9e-14 53.2 42.0 2.1e-13 50.5 17.5 4.3 4 0 0 4 4 4 2 Chitin recognition protein Glyco_hydro_114 PF03537.13 KKK23992.1 - 0.0077 15.6 0.0 0.24 10.7 0.0 2.8 2 1 0 2 2 2 1 Glycoside-hydrolase family GH114 Ank_2 PF12796.7 KKK23993.1 - 8.4e-25 87.2 0.0 4.2e-09 36.9 0.0 4.3 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KKK23993.1 - 1.6e-15 57.2 4.6 3.4e-05 24.3 0.0 6.9 4 2 4 8 8 8 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KKK23993.1 - 5.4e-13 47.9 3.5 0.15 12.7 0.1 7.6 8 0 0 8 8 8 3 Ankyrin repeat Ank PF00023.30 KKK23993.1 - 9.1e-10 38.5 6.3 0.055 13.9 0.0 6.5 7 1 0 7 7 7 3 Ankyrin repeat Ank_5 PF13857.6 KKK23993.1 - 4.4e-08 33.2 0.3 0.15 12.4 0.0 5.7 4 1 2 6 6 6 2 Ankyrin repeats (many copies) MFS_2 PF13347.6 KKK23994.1 - 0.03 12.9 1.9 0.033 12.8 1.9 1.0 1 0 0 1 1 1 0 MFS/sugar transport protein Abhydrolase_2 PF02230.16 KKK23994.1 - 0.2 11.5 0.1 0.2 11.5 0.1 1.1 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase OapA_N PF08525.11 KKK23994.1 - 5.5 7.0 10.4 0.24 11.4 4.5 1.9 2 0 0 2 2 2 0 Opacity-associated protein A N-terminal motif Kinesin PF00225.23 KKK23995.1 - 1.4e-80 270.8 2.9 1.4e-80 270.8 2.9 2.2 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KKK23995.1 - 4.7e-22 78.5 0.0 1.1e-21 77.4 0.0 1.7 1 0 0 1 1 1 1 Microtubule binding HHH PF00633.23 KKK23995.1 - 1.4e-06 27.9 0.9 0.042 13.7 0.0 3.2 3 0 0 3 3 3 2 Helix-hairpin-helix motif HHH_5 PF14520.6 KKK23995.1 - 0.00043 20.8 0.0 1.7 9.3 0.0 2.9 2 0 0 2 2 2 2 Helix-hairpin-helix domain TPR_15 PF13429.6 KKK23995.1 - 0.0069 15.6 1.1 0.012 14.9 1.1 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat HHH_3 PF12836.7 KKK23995.1 - 0.026 14.8 1.3 3.9 7.8 0.0 3.2 3 0 0 3 3 3 0 Helix-hairpin-helix motif Spore_YhcN_YlaJ PF09580.10 KKK23995.1 - 0.056 13.5 0.2 0.16 12.1 0.2 1.7 1 0 0 1 1 1 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) DUF2462 PF09495.10 KKK23995.1 - 0.1 13.3 3.4 2 9.2 0.3 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2462) DUF4435 PF14491.6 KKK23995.1 - 0.43 10.4 2.9 3.6 7.4 0.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4435) Methyltransf_23 PF13489.6 KKK23996.1 - 3.2e-16 59.6 0.0 4e-16 59.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKK23996.1 - 2.4e-13 50.6 0.0 5e-13 49.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KKK23996.1 - 1e-12 48.5 0.0 2e-12 47.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KKK23996.1 - 2.6e-10 40.9 0.0 4.1e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KKK23996.1 - 1.2e-09 38.1 0.0 2.2e-09 37.3 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KKK23996.1 - 2.7e-05 23.6 0.1 6.2e-05 22.5 0.0 1.6 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family tRNA_U5-meth_tr PF05958.11 KKK23996.1 - 0.0035 16.4 0.0 0.0049 15.9 0.0 1.2 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase PCI PF01399.27 KKK23997.1 - 2.1e-08 34.6 0.0 4.9e-08 33.4 0.0 1.7 1 0 0 1 1 1 1 PCI domain Rpn9_C PF18261.1 KKK23997.1 - 0.00013 21.4 0.8 0.00032 20.2 0.8 1.6 1 0 0 1 1 1 1 Rpn9 C-terminal helix HEM4 PF02602.15 KKK23998.1 - 1.6e-35 122.5 0.0 2e-34 119.0 0.0 2.0 1 1 0 1 1 1 1 Uroporphyrinogen-III synthase HemD Pkinase PF00069.25 KKK23999.1 - 9.6e-68 228.4 0.0 1.2e-67 228.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK23999.1 - 2.5e-32 112.2 0.0 3.3e-32 111.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KKK23999.1 - 0.00036 19.9 0.2 0.00059 19.2 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KKK23999.1 - 0.0029 16.6 0.1 0.005 15.8 0.1 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KKK23999.1 - 0.0096 15.3 0.0 0.018 14.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KKK23999.1 - 0.035 14.0 0.1 0.058 13.3 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KKK23999.1 - 0.073 12.1 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Epimerase PF01370.21 KKK24000.1 - 6.7e-14 51.9 0.0 2.2e-13 50.2 0.0 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KKK24000.1 - 1.5e-11 44.3 0.0 4.4e-09 36.2 0.0 2.1 2 0 0 2 2 2 2 NmrA-like family NAD_binding_10 PF13460.6 KKK24000.1 - 1.1e-09 38.5 0.0 2.3e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KKK24000.1 - 2.7e-09 36.4 0.1 5.3e-09 35.5 0.1 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KKK24000.1 - 4.4e-08 32.9 0.1 2.4e-07 30.5 0.1 1.9 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase adh_short PF00106.25 KKK24000.1 - 4.1e-05 23.1 0.0 6.6e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KKK24000.1 - 0.006 16.2 0.0 0.0091 15.6 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_4 PF07993.12 KKK24000.1 - 0.0086 15.3 0.1 0.019 14.2 0.1 1.5 1 0 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.17 KKK24000.1 - 0.01 15.0 0.0 0.1 11.7 0.0 2.2 1 1 1 2 2 2 0 RmlD substrate binding domain DDE_Tnp_1_3 PF13612.6 KKK24000.1 - 0.15 12.1 0.0 0.31 11.0 0.0 1.6 2 0 0 2 2 2 0 Transposase DDE domain DLH PF01738.18 KKK24001.1 - 1.6e-23 83.4 0.0 1.9e-23 83.2 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 KKK24001.1 - 0.0018 18.0 0.0 0.002 17.8 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Sec23_trunk PF04811.15 KKK24002.1 - 4.4e-70 236.0 0.0 8.7e-70 235.0 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 KKK24002.1 - 1.6e-22 79.3 0.0 5.8e-22 77.5 0.0 2.0 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 KKK24002.1 - 7e-17 61.9 0.0 1.8e-16 60.7 0.0 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 KKK24002.1 - 1.4e-16 60.2 4.7 2.5e-16 59.4 4.7 1.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 KKK24002.1 - 5.2e-09 35.9 0.0 1.3e-08 34.6 0.0 1.7 1 0 0 1 1 1 1 Gelsolin repeat Vps36-NZF-N PF16988.5 KKK24002.1 - 0.02 14.3 0.1 0.042 13.2 0.1 1.4 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Gaa1 PF04114.14 KKK24003.1 - 2.4e-186 620.6 2.9 3.7e-186 620.0 2.9 1.3 1 0 0 1 1 1 1 Gaa1-like, GPI transamidase component Rhomboid PF01694.22 KKK24003.1 - 4.2e-14 52.8 8.8 4.2e-14 52.8 8.8 3.0 4 0 0 4 4 4 1 Rhomboid family ATG11 PF10377.9 KKK24010.1 - 1.1e-45 154.9 0.0 1.1e-45 154.9 0.0 3.9 3 0 0 3 3 3 1 Autophagy-related protein 11 rRNA_methylase PF06962.12 KKK24010.1 - 0.059 13.4 0.0 0.27 11.2 0.0 2.2 1 1 0 1 1 1 0 Putative rRNA methylase Bcr-Abl_Oligo PF09036.10 KKK24010.1 - 1.8 8.6 13.0 0.16 12.0 0.2 4.0 3 0 0 3 3 3 0 Bcr-Abl oncoprotein oligomerisation domain HMMR_N PF15905.5 KKK24010.1 - 8 5.8 58.0 0.15 11.5 19.6 3.7 3 0 0 3 3 3 0 Hyaluronan mediated motility receptor N-terminal DUF3584 PF12128.8 KKK24010.1 - 8.8 3.7 60.7 1 6.7 40.7 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) TPR_1 PF00515.28 KKK24012.1 - 4.6e-32 108.5 12.6 1.2e-06 28.0 0.0 7.5 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_2 PF07719.17 KKK24012.1 - 7.1e-32 106.9 12.5 2.8e-05 23.9 0.0 7.8 7 0 0 7 7 7 6 Tetratricopeptide repeat DnaJ PF00226.31 KKK24012.1 - 1.2e-26 92.6 2.6 2.9e-26 91.4 1.3 2.3 2 0 0 2 2 2 1 DnaJ domain TPR_19 PF14559.6 KKK24012.1 - 8.8e-23 80.6 17.6 1.3e-08 35.2 0.3 5.9 4 2 0 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.6 KKK24012.1 - 1.5e-21 74.7 6.3 0.0013 18.8 0.0 7.3 6 1 0 7 7 7 5 Tetratricopeptide repeat TPR_16 PF13432.6 KKK24012.1 - 6.7e-17 61.9 23.7 0.00022 21.8 4.0 6.5 4 2 2 6 6 5 5 Tetratricopeptide repeat TPR_11 PF13414.6 KKK24012.1 - 7.5e-14 51.1 14.7 3.2e-05 23.5 0.1 6.8 5 1 1 6 6 6 4 TPR repeat TPR_7 PF13176.6 KKK24012.1 - 6.2e-13 47.8 2.7 0.2 11.8 0.0 6.6 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.6 KKK24012.1 - 3.9e-12 45.6 9.9 0.034 14.5 0.0 6.2 5 0 0 5 5 5 3 Tetratricopeptide repeat ANAPC3 PF12895.7 KKK24012.1 - 4.1e-12 46.1 3.0 0.13 12.5 0.1 5.0 3 2 2 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 KKK24012.1 - 1.1e-11 44.5 24.5 0.018 15.8 0.1 8.2 6 2 3 9 9 7 3 Tetratricopeptide repeat TPR_9 PF13371.6 KKK24012.1 - 3.8e-11 43.0 10.3 0.00047 20.3 0.1 4.2 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_6 PF13174.6 KKK24012.1 - 1.1e-09 38.2 12.0 0.028 15.0 0.1 7.9 8 1 0 8 8 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 KKK24012.1 - 4.6e-07 30.0 11.7 0.27 11.5 0.8 6.1 4 2 0 5 5 5 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KKK24012.1 - 4.7e-07 29.8 3.6 0.56 10.3 0.1 4.4 4 0 0 4 4 4 2 Fis1 C-terminal tetratricopeptide repeat TPR_15 PF13429.6 KKK24012.1 - 5.8e-05 22.4 5.9 0.97 8.6 0.0 4.8 3 2 1 4 4 4 1 Tetratricopeptide repeat BTAD PF03704.17 KKK24012.1 - 0.00012 22.5 9.1 0.2 12.1 0.6 4.2 3 1 0 4 4 3 2 Bacterial transcriptional activator domain TPR_10 PF13374.6 KKK24012.1 - 0.00029 20.6 14.5 3 7.8 0.1 6.0 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_20 PF14561.6 KKK24012.1 - 0.0012 19.2 6.8 5.2 7.5 0.3 4.3 3 1 1 4 4 4 1 Tetratricopeptide repeat DUF4919 PF16266.5 KKK24012.1 - 0.003 17.5 1.4 3.5 7.5 0.1 3.6 3 1 0 3 3 3 1 Domain of unknown function (DUF4919) SRP_TPR_like PF17004.5 KKK24012.1 - 0.015 15.3 0.0 3.2 7.8 0.0 3.3 3 0 0 3 3 3 0 Putative TPR-like repeat SHNi-TPR PF10516.9 KKK24012.1 - 0.019 14.4 6.1 31 4.1 0.0 5.1 5 0 0 5 5 5 0 SHNi-TPR DUF5588 PF17826.1 KKK24012.1 - 0.019 13.9 0.2 1.5 7.6 0.0 2.9 3 0 0 3 3 3 0 Family of unknown function (DUF5588) MIT PF04212.18 KKK24012.1 - 0.11 12.6 4.1 1.9 8.7 0.1 3.5 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_4 PF07721.14 KKK24012.1 - 0.12 13.1 16.7 0.24 12.1 0.1 4.7 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_MalT PF17874.1 KKK24012.1 - 0.17 11.2 1.9 13 5.0 0.0 3.1 3 0 0 3 3 3 0 MalT-like TPR region Ribonuc_L-PSP PF01042.21 KKK24014.1 - 5.1e-17 62.0 0.0 8.1e-17 61.4 0.0 1.3 1 1 0 1 1 1 1 Endoribonuclease L-PSP Amidohydro_2 PF04909.14 KKK24015.1 - 1e-44 153.5 0.1 1.2e-44 153.2 0.1 1.0 1 0 0 1 1 1 1 Amidohydrolase Aldedh PF00171.22 KKK24016.1 - 4.4e-145 483.7 0.0 5.1e-145 483.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family UL2 PF08196.11 KKK24016.1 - 0.15 12.0 0.1 8.4 6.4 0.0 2.5 2 0 0 2 2 2 0 UL2 protein F-box-like PF12937.7 KKK24017.1 - 0.0046 16.8 0.0 0.0091 15.9 0.0 1.5 1 0 0 1 1 1 1 F-box-like CHORD PF04968.12 KKK24018.1 - 0.6 10.9 0.0 0.6 10.9 0.0 2.8 4 0 0 4 4 4 0 CHORD Cas_CXXC_CXXC PF09706.10 KKK24018.1 - 2.2 8.6 5.7 27 5.1 0.0 3.6 4 0 0 4 4 4 0 CRISPR-associated protein (Cas_CXXC_CXXC) ZZ PF00569.17 KKK24018.1 - 3.9 7.4 10.3 4 7.3 0.1 4.2 5 0 0 5 5 5 0 Zinc finger, ZZ type OSTMP1 PF09777.9 KKK24018.1 - 4.2 6.7 5.9 19 4.6 0.0 3.5 3 1 0 3 3 3 0 Osteopetrosis-associated transmembrane protein 1 precursor Exo_endo_phos PF03372.23 KKK24019.1 - 7.1e-06 25.7 0.0 7.7e-06 25.6 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Fungal_trans PF04082.18 KKK24020.1 - 5.2e-12 45.4 1.5 2.6e-11 43.1 1.4 2.2 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK24020.1 - 8.2e-07 29.1 14.7 1.7e-06 28.1 14.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GMC_oxred_C PF05199.13 KKK24021.1 - 1.1e-33 116.7 1.6 2.3e-32 112.5 0.4 2.3 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_N PF00732.19 KKK24021.1 - 1.3e-31 110.1 0.0 2.1e-28 99.6 0.0 3.0 1 1 1 2 2 2 2 GMC oxidoreductase Pyr_redox_2 PF07992.14 KKK24021.1 - 0.0014 17.9 0.0 0.0022 17.3 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KKK24021.1 - 0.0021 18.3 0.3 0.0078 16.4 0.1 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KKK24021.1 - 0.0026 16.9 0.2 0.0099 15.0 0.5 1.7 2 0 0 2 2 2 1 FAD binding domain NepR PF18557.1 KKK24021.1 - 0.064 12.9 0.1 0.63 9.7 0.0 2.2 2 0 0 2 2 2 0 Anti-sigma factor NepR HI0933_like PF03486.14 KKK24021.1 - 0.19 10.4 0.2 2.3 6.8 0.1 2.0 2 0 0 2 2 2 0 HI0933-like protein ApbA PF02558.16 KKK24021.1 - 0.2 11.3 0.5 0.4 10.3 0.5 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA RVT_1 PF00078.27 KKK24022.1 - 0.058 12.9 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) LysM PF01476.20 KKK24023.1 - 8.6e-23 80.1 0.0 1.4e-06 28.3 0.0 4.2 4 0 0 4 4 4 4 LysM domain CorA PF01544.18 KKK24024.1 - 7.7e-05 22.1 0.6 0.00041 19.8 0.0 2.4 3 0 0 3 3 3 1 CorA-like Mg2+ transporter protein FAA_hydro_N_2 PF18288.1 KKK24024.1 - 0.019 15.3 0.0 0.11 13.0 0.0 2.3 2 0 0 2 2 2 0 Fumarylacetoacetase N-terminal domain 2 MerR-DNA-bind PF09278.11 KKK24024.1 - 1.4 9.5 7.2 0.84 10.2 1.6 2.6 2 0 0 2 2 2 0 MerR, DNA binding FliT PF05400.13 KKK24024.1 - 1.9 9.4 7.0 3.1 8.7 1.3 2.9 2 0 0 2 2 2 0 Flagellar protein FliT CIAPIN1 PF05093.13 KKK24025.1 - 9.9e-42 141.5 2.6 1.7e-41 140.7 2.6 1.4 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis DRE2_N PF16803.5 KKK24025.1 - 8e-37 126.4 0.0 1.1e-36 126.0 0.0 1.2 1 0 0 1 1 1 1 Fe-S cluster assembly protein DRE2 N-terminus RRM_occluded PF16842.5 KKK24035.1 - 5.9e-32 109.4 0.0 1.1e-31 108.6 0.0 1.4 1 0 0 1 1 1 1 Occluded RNA-recognition motif RRM_1 PF00076.22 KKK24035.1 - 3.6e-05 23.5 0.0 6.6e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Lsm_interact PF05391.11 KKK24035.1 - 0.0092 15.4 2.4 0.022 14.2 2.4 1.6 1 0 0 1 1 1 1 Lsm interaction motif C2 PF00168.30 KKK24036.1 - 1.3e-15 57.5 0.0 2.2e-15 56.8 0.0 1.4 1 0 0 1 1 1 1 C2 domain SSP160 PF06933.11 KKK24036.1 - 6.6 4.8 7.0 9.5 4.3 7.0 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 PHD PF00628.29 KKK24050.1 - 1.7e-08 34.2 7.4 2.8e-08 33.5 7.4 1.3 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 KKK24050.1 - 0.38 10.4 5.9 0.66 9.6 5.9 1.4 1 0 0 1 1 1 0 PHD-finger zf-RING_2 PF13639.6 KKK24050.1 - 4.1 7.8 8.0 7.4 7.0 8.0 1.4 1 0 0 1 1 1 0 Ring finger domain zf-RING_11 PF17123.5 KKK24050.1 - 5 7.0 5.8 9.8 6.0 5.8 1.5 1 0 0 1 1 1 0 RING-like zinc finger Pkinase PF00069.25 KKK24051.1 - 8e-66 222.1 0.0 1.5e-65 221.2 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK24051.1 - 2.8e-35 121.9 0.0 5.4e-26 91.4 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 KKK24051.1 - 2.4e-06 26.6 0.1 4.6e-06 25.7 0.1 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KKK24051.1 - 3e-05 23.5 0.5 0.0017 17.8 0.0 2.5 3 0 0 3 3 3 1 Kinase-like APH PF01636.23 KKK24051.1 - 0.0027 17.7 0.0 0.0074 16.2 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family FtsX_ECD PF18075.1 KKK24051.1 - 0.019 15.6 0.0 0.086 13.5 0.0 2.2 1 0 0 1 1 1 0 FtsX extracellular domain Seadorna_VP7 PF07387.11 KKK24051.1 - 0.021 13.9 0.0 0.039 13.0 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 FERM_f0 PF16511.5 KKK24051.1 - 0.07 13.4 0.1 0.25 11.6 0.1 1.9 1 0 0 1 1 1 0 N-terminal or F0 domain of Talin-head FERM FTA2 PF13095.6 KKK24051.1 - 0.14 11.7 0.1 0.53 9.9 0.0 1.9 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Vac_ImportDeg PF09783.9 KKK24052.1 - 1.5e-69 232.9 0.7 1.8e-69 232.7 0.7 1.1 1 0 0 1 1 1 1 Vacuolar import and degradation protein Mago_nashi PF02792.14 KKK24053.1 - 1.4e-73 245.6 0.2 1.8e-73 245.3 0.2 1.1 1 0 0 1 1 1 1 Mago nashi protein DAGK_cat PF00781.24 KKK24054.1 - 1.3e-25 89.4 0.0 2.1e-25 88.8 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Adaptin_N PF01602.20 KKK24055.1 - 1.4e-95 320.9 8.9 2.1e-95 320.3 8.9 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Coatamer_beta_C PF07718.12 KKK24055.1 - 2.5e-58 195.9 0.6 5.6e-58 194.8 0.6 1.6 1 0 0 1 1 1 1 Coatomer beta C-terminal region Coatomer_b_Cpla PF14806.6 KKK24055.1 - 2.8e-56 189.0 0.0 7.5e-56 187.6 0.0 1.8 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Cnd1 PF12717.7 KKK24055.1 - 4.3e-14 52.9 5.0 3.2e-09 37.0 0.1 2.9 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KKK24055.1 - 8.1e-07 29.3 0.2 8.1e-05 22.9 0.0 5.3 3 1 3 6 6 6 3 HEAT repeats Coatomer_g_Cpla PF16381.5 KKK24055.1 - 5.1e-05 23.4 0.0 0.00048 20.2 0.0 2.5 2 0 0 2 2 2 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT PF02985.22 KKK24055.1 - 0.0042 17.2 1.8 1.4 9.3 0.1 4.4 4 0 0 4 4 4 1 HEAT repeat AP4E_app_platf PF14807.6 KKK24055.1 - 0.0061 16.9 0.2 0.024 15.0 0.2 2.1 1 0 0 1 1 1 1 Adaptin AP4 complex epsilon appendage platform HEAT_EZ PF13513.6 KKK24055.1 - 0.075 13.6 0.2 3.9 8.1 0.0 3.7 2 0 0 2 2 2 0 HEAT-like repeat Sugar_tr PF00083.24 KKK24056.1 - 2.9e-127 425.3 29.4 3.3e-127 425.1 29.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKK24056.1 - 7.9e-24 84.2 56.0 4.3e-21 75.2 31.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Phage_holin_3_2 PF04550.12 KKK24056.1 - 0.4 11.2 5.7 0.64 10.6 4.5 2.0 2 0 0 2 2 2 0 Phage holin family 2 Nuc_sug_transp PF04142.15 KKK24057.1 - 9.9e-10 38.1 1.0 1.7e-09 37.3 1.0 1.4 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 KKK24057.1 - 6.1e-09 36.2 28.9 4.5e-05 23.6 5.5 2.6 3 0 0 3 3 3 2 EamA-like transporter family UAA PF08449.11 KKK24057.1 - 3.3e-05 23.2 8.5 5.6e-05 22.5 8.5 1.3 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.16 KKK24057.1 - 9.5e-05 21.9 3.4 0.00041 19.8 0.1 2.4 2 1 0 2 2 2 1 Triose-phosphate Transporter family Proton_antipo_C PF01010.19 KKK24057.1 - 0.0056 16.3 0.1 0.0099 15.5 0.1 1.3 1 0 0 1 1 1 1 NADH-dehyrogenase subunit F, TMs, (complex I) C-terminus DUF3290 PF11694.8 KKK24057.1 - 0.21 11.5 1.2 0.37 10.8 0.0 2.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3290) IncD PF17628.2 KKK24057.1 - 6.5 6.5 8.3 0.41 10.4 0.1 2.9 1 1 0 2 2 2 0 Inclusion membrane protein D Perilipin PF03036.16 KKK24058.1 - 0.023 13.7 0.0 0.029 13.4 0.0 1.1 1 0 0 1 1 1 0 Perilipin family SGP PF17228.2 KKK24058.1 - 1 10.2 6.9 0.13 13.1 2.6 1.7 2 0 0 2 2 2 0 Sulphur globule protein MAGE PF01454.19 KKK24059.1 - 4e-61 206.4 0.1 4e-61 206.4 0.1 1.7 2 0 0 2 2 2 1 MAGE family Adaptin_N PF01602.20 KKK24060.1 - 7.4e-142 473.6 3.2 8.7e-142 473.3 3.2 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 KKK24060.1 - 4.8e-19 68.7 0.0 9.4e-19 67.8 0.0 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain Cnd1 PF12717.7 KKK24060.1 - 1.1e-08 35.3 5.0 0.00022 21.3 0.1 4.3 2 1 2 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KKK24060.1 - 3.8e-06 27.2 3.1 0.08 13.3 0.0 3.9 4 0 0 4 4 4 2 HEAT repeats HEAT PF02985.22 KKK24060.1 - 0.0026 17.9 1.8 6.6 7.3 0.1 4.3 4 0 0 4 4 4 1 HEAT repeat HEAT_EZ PF13513.6 KKK24060.1 - 0.016 15.7 0.1 26 5.4 0.0 4.8 4 0 0 4 4 4 0 HEAT-like repeat RICTOR_M PF14666.6 KKK24060.1 - 0.02 14.7 0.4 0.088 12.6 0.1 2.3 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR, middle domain Cohesin_HEAT PF12765.7 KKK24060.1 - 0.19 12.1 0.7 0.56 10.6 0.2 2.2 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion MBOAT PF03062.19 KKK24061.1 - 2.2e-41 142.3 15.6 2.2e-41 142.3 15.6 2.1 2 0 0 2 2 2 2 MBOAT, membrane-bound O-acyltransferase family Med15_fungi PF05397.12 KKK24062.1 - 4.7e-33 113.8 0.1 4.7e-33 113.8 0.1 7.0 6 1 0 6 6 6 1 Mediator complex subunit 15 KIX_2 PF16987.5 KKK24062.1 - 1.9e-10 40.6 0.7 1.9e-10 40.6 0.7 4.4 4 1 0 4 4 4 1 KIX domain LMBR1 PF04791.16 KKK24063.1 - 1.7e-133 446.3 4.3 2.2e-133 445.9 4.3 1.1 1 0 0 1 1 1 1 LMBR1-like membrane protein BAG PF02179.16 KKK24063.1 - 5.8e-10 39.5 0.0 1.1e-09 38.5 0.0 1.4 1 0 0 1 1 1 1 BAG domain ubiquitin PF00240.23 KKK24063.1 - 0.00033 20.4 0.0 0.00061 19.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family FUSC PF04632.12 KKK24063.1 - 0.0045 15.6 0.8 0.0045 15.6 0.8 2.3 2 0 0 2 2 2 1 Fusaric acid resistance protein family DUF202 PF02656.15 KKK24063.1 - 0.19 12.2 0.1 0.19 12.2 0.1 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF202) DUF2142 PF09913.9 KKK24063.1 - 0.35 9.7 11.8 1.3 7.8 11.8 2.0 1 1 0 1 1 1 0 Predicted membrane protein (DUF2142) SUIM_assoc PF16619.5 KKK24063.1 - 0.61 10.2 3.6 1.5 8.9 3.6 1.6 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Glutaredoxin PF00462.24 KKK24066.1 - 2.1e-21 75.9 0.0 3e-21 75.4 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_2 PF13098.6 KKK24066.1 - 0.00087 19.7 0.0 0.0014 19.1 0.0 1.3 1 1 0 1 1 1 1 Thioredoxin-like domain DUF836 PF05768.14 KKK24066.1 - 0.0011 19.4 0.0 0.0013 19.1 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin PF00085.20 KKK24066.1 - 0.014 15.4 0.0 0.015 15.3 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin TraF PF13728.6 KKK24066.1 - 0.041 13.7 0.0 0.044 13.6 0.0 1.2 1 0 0 1 1 1 0 F plasmid transfer operon protein SRP14 PF02290.15 KKK24066.1 - 0.06 13.7 0.0 0.32 11.4 0.0 1.9 2 0 0 2 2 2 0 Signal recognition particle 14kD protein GST_N_3 PF13417.6 KKK24066.1 - 0.078 13.4 0.0 0.12 12.7 0.0 1.4 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain DSBA PF01323.20 KKK24066.1 - 0.08 12.7 0.3 0.34 10.6 0.2 1.8 1 1 1 2 2 2 0 DSBA-like thioredoxin domain Chalcone_2 PF16035.5 KKK24067.1 - 1.6e-60 204.4 0.0 2.8e-60 203.6 0.0 1.4 1 0 0 1 1 1 1 Chalcone isomerase like Chalcone_3 PF16036.5 KKK24067.1 - 0.0015 18.7 0.0 0.0048 17.0 0.0 1.8 2 1 0 2 2 2 1 Chalcone isomerase-like Ank_3 PF13606.6 KKK24068.1 - 8.2e-08 31.9 0.0 0.033 14.7 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 KKK24068.1 - 1.2e-07 32.3 0.0 6.7e-07 29.8 0.0 2.1 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KKK24068.1 - 1.1e-06 28.7 0.1 0.0057 16.9 0.0 3.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KKK24068.1 - 1.9e-05 24.9 0.0 0.02 15.3 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 KKK24068.1 - 0.001 19.6 0.0 0.0028 18.2 0.0 1.8 1 1 0 1 1 1 1 Ankyrin repeats (many copies) GTP_EFTU PF00009.27 KKK24069.1 - 1.3e-53 181.5 0.0 2.1e-53 180.8 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain PALP PF00291.25 KKK24069.1 - 2.8e-52 178.0 0.4 4e-52 177.4 0.4 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme GTP_EFTU_D3 PF03143.17 KKK24069.1 - 1.6e-40 137.9 0.0 3.3e-40 136.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 KKK24069.1 - 1.9e-13 50.6 1.3 8.2e-13 48.5 1.3 2.2 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KKK24069.1 - 0.0024 17.9 0.1 0.047 13.8 0.1 2.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.6 KKK24069.1 - 0.054 13.4 0.6 0.16 11.9 0.6 1.7 1 0 0 1 1 1 0 Elongation factor Tu domain 4 ADH_zinc_N PF00107.26 KKK24069.1 - 0.076 13.0 0.1 0.38 10.7 0.0 2.3 2 0 0 2 2 2 0 Zinc-binding dehydrogenase Cyt-b5 PF00173.28 KKK24071.1 - 1.5e-22 79.5 0.1 2e-22 79.1 0.1 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain YqzH PF14164.6 KKK24071.1 - 0.11 12.6 0.1 0.18 11.9 0.1 1.4 1 0 0 1 1 1 0 YqzH-like protein UCH PF00443.29 KKK24072.1 - 3.7e-50 170.8 0.0 5.5e-50 170.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KKK24072.1 - 2.2e-16 60.4 1.4 8.6e-14 51.8 0.1 2.4 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Rhodanese PF00581.20 KKK24072.1 - 3.4e-05 24.3 0.0 8.6e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain USP8_dimer PF08969.11 KKK24074.1 - 0.00026 21.1 0.0 0.00035 20.7 0.0 1.1 1 0 0 1 1 1 1 USP8 dimerisation domain VHS PF00790.19 KKK24075.1 - 1.2e-40 138.6 0.7 1.5e-39 135.1 0.0 2.2 2 0 0 2 2 2 1 VHS domain FYVE PF01363.21 KKK24075.1 - 5e-16 58.6 1.3 7.9e-16 58.0 1.3 1.3 1 0 0 1 1 1 1 FYVE zinc finger UIM PF02809.20 KKK24075.1 - 1.6e-05 24.5 13.2 0.0047 16.7 2.7 2.7 2 0 0 2 2 2 2 Ubiquitin interaction motif GAT PF03127.14 KKK24075.1 - 2.3e-05 24.6 0.0 0.00012 22.3 0.0 2.2 2 0 0 2 2 2 1 GAT domain FYVE_2 PF02318.16 KKK24075.1 - 0.071 13.3 0.4 0.14 12.3 0.4 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger Npa1 PF11707.8 KKK24075.1 - 0.072 12.4 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Ribosome 60S biogenesis N-terminal DZR PF12773.7 KKK24075.1 - 0.27 11.3 2.3 0.52 10.4 2.3 1.4 1 0 0 1 1 1 0 Double zinc ribbon OrfB_Zn_ribbon PF07282.11 KKK24075.1 - 0.68 9.9 2.8 2.9 7.9 3.1 1.8 2 0 0 2 2 2 0 Putative transposase DNA-binding domain ADH_N PF08240.12 KKK24077.1 - 7.7e-22 77.2 2.0 7.7e-22 77.2 2.0 1.6 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KKK24077.1 - 9.9e-05 22.3 0.0 0.59 10.1 0.0 2.8 3 0 0 3 3 3 2 Zinc-binding dehydrogenase ADH_N_assoc PF13823.6 KKK24077.1 - 0.037 14.0 0.0 0.07 13.1 0.0 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-associated Glu_dehyd_C PF16912.5 KKK24077.1 - 0.055 13.0 0.0 0.49 9.9 0.0 2.4 2 1 1 3 3 3 0 Glucose dehydrogenase C-terminus Abhydrolase_1 PF00561.20 KKK24078.1 - 4e-11 43.0 0.0 2.1e-08 34.1 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KKK24078.1 - 1.1e-06 28.2 0.0 1.4e-05 24.5 0.0 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KKK24078.1 - 1.2e-06 29.3 0.0 1.4e-06 29.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.14 KKK24078.1 - 6.8e-05 21.7 0.0 0.00018 20.3 0.0 1.7 1 1 0 1 1 1 1 Ndr family adh_short PF00106.25 KKK24079.1 - 4.3e-12 45.9 0.0 1.4e-06 27.9 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KKK24079.1 - 2.7e-07 30.4 0.0 0.00027 20.6 0.0 2.0 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase Ribonuclease_3 PF00636.26 KKK24080.1 - 0.00049 20.7 0.0 0.0033 18.0 0.0 2.0 1 1 0 1 1 1 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 KKK24080.1 - 0.0091 16.2 0.0 0.013 15.7 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease-III-like Sugar_tr PF00083.24 KKK24081.1 - 4.5e-107 358.7 22.5 5.3e-107 358.5 22.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKK24081.1 - 5.7e-26 91.3 35.2 9.1e-19 67.6 8.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KKK24081.1 - 0.00012 20.8 3.3 0.00012 20.8 3.3 3.3 2 2 1 3 3 3 2 MFS/sugar transport protein MFS_3 PF05977.13 KKK24081.1 - 0.0089 14.5 0.1 0.0089 14.5 0.1 1.9 2 0 0 2 2 2 1 Transmembrane secretion effector YebO PF13974.6 KKK24081.1 - 6.3 6.9 5.9 28 4.9 1.0 2.6 2 0 0 2 2 2 0 YebO-like protein Metallophos PF00149.28 KKK24082.1 - 9.8e-10 39.3 0.0 2.1e-09 38.2 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KKK24082.1 - 6.5e-07 29.7 0.0 1.6e-05 25.2 0.0 2.3 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain tRNA_U5-meth_tr PF05958.11 KKK24089.1 - 1.6e-11 43.8 0.0 1.3e-09 37.5 0.0 2.2 1 1 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_25 PF13649.6 KKK24089.1 - 0.0082 16.8 0.0 0.02 15.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KKK24089.1 - 0.036 13.9 0.0 0.27 11.0 0.0 2.3 3 0 0 3 3 3 0 Methyltransferase domain Ribosomal_S5_C PF03719.15 KKK24090.1 - 6.7e-26 89.5 0.1 5.8e-25 86.5 0.0 2.1 2 0 0 2 2 2 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.20 KKK24090.1 - 4e-18 65.2 0.3 1.5e-17 63.3 0.0 2.2 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Fungal_trans_2 PF11951.8 KKK24092.1 - 2.2e-11 43.2 0.7 1.1e-10 40.9 0.7 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain DUF1908 PF08926.11 KKK24092.1 - 0.059 12.4 6.4 0.039 13.0 4.6 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF1908) Gpr1_Fun34_YaaH PF01184.19 KKK24093.1 - 2.1e-70 236.6 16.8 2.5e-70 236.3 16.8 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family HTH_Tnp_1_2 PF13022.6 KKK24109.1 - 0.034 14.3 0.1 0.037 14.2 0.1 1.1 1 0 0 1 1 1 0 Helix-turn-helix of insertion element transposase APH PF01636.23 KKK24110.1 - 1.5e-09 38.1 0.0 2.6e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KKK24110.1 - 1.5e-05 24.7 0.0 2.5e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase CorA PF01544.18 KKK24128.1 - 4.7e-10 39.3 0.2 8.9e-10 38.4 0.2 1.5 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Gly_transf_sug PF04488.15 KKK24129.1 - 4.3e-13 49.7 0.0 1.3e-12 48.2 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif CUB PF00431.20 KKK24129.1 - 0.047 14.0 0.0 0.081 13.3 0.0 1.3 1 0 0 1 1 1 0 CUB domain CALM_bind PF16025.5 KKK24139.1 - 0.075 13.5 6.3 0.17 12.4 6.3 1.6 1 0 0 1 1 1 0 Calcium-dependent calmodulin binding Actin PF00022.19 KKK24140.1 - 2.2e-128 428.4 0.0 1.2e-127 425.9 0.0 1.8 1 1 0 1 1 1 1 Actin DUF4332 PF14229.6 KKK24140.1 - 0.16 12.2 0.0 0.3 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4332) MRP-S28 PF10213.9 KKK24141.1 - 1.8e-46 157.7 0.0 3.4e-46 156.8 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein CcdA PF07362.12 KKK24141.1 - 0.92 10.0 5.9 13 6.3 0.1 2.9 3 0 0 3 3 3 0 Post-segregation antitoxin CcdA Glyco_tran_28_C PF04101.16 KKK24142.1 - 7.5e-16 58.6 0.0 4.6e-13 49.5 0.0 2.1 2 0 0 2 2 2 2 Glycosyltransferase family 28 C-terminal domain UDPGT PF00201.18 KKK24142.1 - 0.014 14.2 0.0 0.019 13.8 0.0 1.1 1 0 0 1 1 1 0 UDP-glucoronosyl and UDP-glucosyl transferase OSR1_C PF12202.8 KKK24142.1 - 0.1 12.8 0.0 0.18 12.0 0.0 1.3 1 0 0 1 1 1 0 Oxidative-stress-responsive kinase 1 C-terminal domain zf-PHD-like PF15446.6 KKK24143.1 - 3.3e-62 209.0 6.6 9.1e-62 207.6 6.6 1.8 1 0 0 1 1 1 1 PHD/FYVE-zinc-finger like domain SNF2_N PF00176.23 KKK24143.1 - 5e-53 180.1 0.1 9e-53 179.2 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-CCCH_6 PF18585.1 KKK24143.1 - 1.2e-24 86.0 0.4 4.3e-24 84.2 0.4 2.1 1 0 0 1 1 1 1 Chromatin remodeling factor Mit1 C-terminal Zn finger 2 Helicase_C PF00271.31 KKK24143.1 - 5.2e-17 62.2 0.0 1.4e-16 60.8 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Chromo PF00385.24 KKK24143.1 - 1.7e-09 37.4 2.5 4.1e-05 23.4 0.5 3.0 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain HDA2-3 PF11496.8 KKK24143.1 - 1.1e-08 34.6 3.2 3e-08 33.2 3.1 1.6 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 PHD PF00628.29 KKK24143.1 - 1.8e-06 27.7 4.0 1.8e-06 27.7 4.0 3.3 2 1 1 3 3 3 1 PHD-finger ResIII PF04851.15 KKK24143.1 - 2.1e-05 24.6 0.0 8.8e-05 22.6 0.0 2.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit C1_1 PF00130.22 KKK24143.1 - 0.0012 18.7 8.4 0.021 14.7 1.9 3.6 3 0 0 3 3 3 1 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF1087 PF06465.13 KKK24143.1 - 0.0073 16.3 1.9 0.023 14.7 1.9 1.8 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1087) NapB PF03892.14 KKK24143.1 - 0.31 11.1 3.3 3.5 7.7 0.2 3.2 3 0 0 3 3 2 0 Nitrate reductase cytochrome c-type subunit (NapB) zf-ANAPC11 PF12861.7 KKK24143.1 - 0.84 9.7 3.9 6.9 6.8 0.4 2.8 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Zf_RING PF16744.5 KKK24143.1 - 0.98 9.6 8.4 1.6 8.9 3.3 2.8 2 0 0 2 2 2 0 KIAA1045 RING finger PHD_2 PF13831.6 KKK24143.1 - 1.6 8.4 11.6 0.098 12.2 3.8 3.0 2 1 0 2 2 2 0 PHD-finger PHD_4 PF16866.5 KKK24143.1 - 7.5 6.7 11.5 16 5.7 3.0 3.6 2 1 0 2 2 2 0 PHD-finger Velvet PF11754.8 KKK24144.1 - 2.6e-41 142.2 1.5 3.9e-29 102.3 0.2 3.6 2 2 1 3 3 3 2 Velvet factor SpoU_methylase PF00588.19 KKK24145.1 - 4.6e-25 88.4 0.0 4e-24 85.4 0.0 2.2 1 1 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.12 KKK24145.1 - 1.5e-08 34.8 0.0 2.9e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding K_channel_TID PF07941.11 KKK24146.1 - 0.21 12.0 10.4 0.38 11.2 10.4 1.4 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain Androgen_recep PF02166.16 KKK24146.1 - 0.28 10.0 6.1 0.35 9.7 6.1 1.1 1 0 0 1 1 1 0 Androgen receptor Ribosomal_60s PF00428.19 KKK24146.1 - 0.99 10.0 10.7 1.2 9.8 9.4 1.8 2 0 0 2 2 2 0 60s Acidic ribosomal protein Torus PF16131.5 KKK24147.1 - 0.062 14.0 0.1 0.13 13.0 0.1 1.5 1 0 0 1 1 1 0 Torus domain PAP2 PF01569.21 KKK24148.1 - 1.2e-13 50.9 4.2 1.2e-13 50.9 4.2 2.3 1 1 1 2 2 2 1 PAP2 superfamily DUF212 PF02681.14 KKK24148.1 - 0.00024 21.2 0.1 0.06 13.5 0.0 2.4 2 1 0 2 2 2 2 Divergent PAP2 family Dpy-30 PF05186.13 KKK24148.1 - 0.72 9.6 2.9 2.3 8.0 0.4 2.4 2 0 0 2 2 2 0 Dpy-30 motif DUF3402 PF11882.8 KKK24149.1 - 6.5e-196 651.9 0.0 8.9e-196 651.5 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3402) N1221 PF07923.13 KKK24149.1 - 2.9e-90 302.4 0.0 4.6e-90 301.7 0.0 1.3 1 0 0 1 1 1 1 N1221-like protein RWD PF05773.22 KKK24150.1 - 5.5e-20 71.8 0.0 9.2e-20 71.1 0.0 1.4 1 0 0 1 1 1 1 RWD domain IBR PF01485.21 KKK24150.1 - 1.1e-19 70.3 38.1 1.8e-15 56.9 3.9 4.0 3 1 1 4 4 4 3 IBR domain, a half RING-finger domain zf-RING_2 PF13639.6 KKK24150.1 - 0.0049 17.2 9.6 0.0049 17.2 9.6 4.0 3 1 1 4 4 4 2 Ring finger domain Amidohydro_1 PF01979.20 KKK24168.1 - 4e-26 92.2 0.0 1.6e-25 90.2 0.0 1.9 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KKK24168.1 - 4e-12 46.4 0.0 3.9e-07 29.9 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family Rad21_Rec8_N PF04825.13 KKK24170.1 - 2.1e-37 127.7 0.1 3.8e-37 126.8 0.1 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 KKK24170.1 - 1.9e-07 30.3 0.2 4.1e-07 29.2 0.2 1.6 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein SMC_ScpA PF02616.14 KKK24170.1 - 0.024 14.6 0.2 0.072 13.0 0.1 1.8 2 0 0 2 2 2 0 Segregation and condensation protein ScpA MFS_1 PF07690.16 KKK24171.1 - 3.1e-43 148.1 29.7 3.1e-43 148.1 29.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KKK24171.1 - 1.7e-07 30.1 3.0 3.5e-07 29.0 3.0 1.5 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.13 KKK24171.1 - 0.0028 16.1 0.7 0.0043 15.5 0.7 1.2 1 0 0 1 1 1 1 Transmembrane secretion effector Ammonium_transp PF00909.21 KKK24172.1 - 6.4e-118 393.9 31.9 7.4e-118 393.7 31.9 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Flavokinase PF01687.17 KKK24173.1 - 5.3e-22 78.2 0.0 1.2e-21 77.1 0.0 1.6 1 0 0 1 1 1 1 Riboflavin kinase Zn_clus PF00172.18 KKK24173.1 - 0.01 16.0 9.2 0.023 14.8 9.2 1.7 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS PF00989.25 KKK24173.1 - 0.095 12.7 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 PAS fold ETRAMP PF09716.10 KKK24173.1 - 0.14 12.2 0.1 0.3 11.2 0.1 1.5 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Hexokinase_2 PF03727.16 KKK24174.1 - 1.1e-79 267.3 0.0 1.4e-79 266.9 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 KKK24174.1 - 8.5e-72 241.2 0.0 1.2e-71 240.8 0.0 1.2 1 0 0 1 1 1 1 Hexokinase PhnJ PF06007.11 KKK24174.1 - 0.064 12.3 0.0 0.1 11.6 0.0 1.3 1 0 0 1 1 1 0 Phosphonate metabolism protein PhnJ COG4 PF08318.12 KKK24175.1 - 1.1e-127 425.8 0.0 2.1e-127 424.8 0.0 1.5 2 0 0 2 2 2 1 COG4 transport protein FA_desaturase PF00487.24 KKK24175.1 - 0.003 17.4 4.1 0.005 16.7 4.1 1.2 1 0 0 1 1 1 1 Fatty acid desaturase NHase_alpha PF02979.16 KKK24175.1 - 0.17 11.2 0.0 0.4 10.0 0.0 1.6 1 0 0 1 1 1 0 Nitrile hydratase, alpha chain SIR2 PF02146.17 KKK24176.1 - 3.1e-55 186.8 0.0 4.2e-55 186.4 0.0 1.2 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.22 KKK24176.1 - 0.095 12.4 0.0 4.1 7.2 0.0 2.5 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain WD40 PF00400.32 KKK24177.1 - 3.8e-07 30.7 0.4 0.007 17.2 0.0 4.8 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKK24177.1 - 0.013 15.8 0.1 8.4 6.8 0.0 3.9 3 2 2 5 5 5 0 Anaphase-promoting complex subunit 4 WD40 domain E1-E2_ATPase PF00122.20 KKK24178.1 - 6.1e-45 153.0 0.4 6.1e-45 153.0 0.4 2.4 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 KKK24178.1 - 3.3e-43 147.5 3.4 4.9e-43 147.0 0.1 2.5 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Cation_ATPase_N PF00690.26 KKK24178.1 - 1.6e-19 69.3 0.1 3.8e-19 68.1 0.1 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase PF00702.26 KKK24178.1 - 3.3e-19 70.0 4.1 7e-18 65.7 4.1 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KKK24178.1 - 7.3e-13 48.4 0.0 1.5e-12 47.4 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KKK24178.1 - 3.7e-06 26.9 1.0 9.5e-05 22.3 0.9 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Ribosomal_L21e PF01157.18 KKK24187.1 - 5.4e-45 151.4 5.7 5.4e-45 151.4 5.7 1.9 2 0 0 2 2 2 1 Ribosomal protein L21e SH3_13 PF18335.1 KKK24187.1 - 0.03 14.1 0.9 0.047 13.5 0.2 1.7 2 1 0 2 2 2 0 ATP-dependent RecD-like DNA helicase SH3 domain 3H PF02829.14 KKK24187.1 - 0.096 13.0 0.2 0.096 13.0 0.2 1.6 2 0 0 2 2 2 0 3H domain WD40 PF00400.32 KKK24188.1 - 3.5e-18 65.6 16.6 0.00058 20.6 0.4 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat Cytochrom_D1 PF02239.16 KKK24188.1 - 4.5e-05 22.2 0.6 0.21 10.1 0.0 3.8 3 1 1 4 4 4 2 Cytochrome D1 heme domain PQQ_3 PF13570.6 KKK24188.1 - 0.0012 19.2 3.1 0.58 10.7 0.1 3.7 3 0 0 3 3 3 2 PQQ-like domain ANAPC4_WD40 PF12894.7 KKK24188.1 - 0.0043 17.3 0.0 0.18 12.1 0.0 3.4 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KKK24188.1 - 0.013 14.9 0.6 0.97 8.7 0.0 2.9 3 0 0 3 3 3 0 WD40-like domain BUD22 PF09073.10 KKK24188.1 - 6.8 5.9 6.9 10 5.4 6.9 1.2 1 0 0 1 1 1 0 BUD22 RRM_1 PF00076.22 KKK24189.1 - 0.0024 17.7 0.0 0.0043 16.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PX PF00787.24 KKK24190.1 - 2.2e-27 95.3 0.2 2.7e-27 95.0 0.2 1.1 1 0 0 1 1 1 1 PX domain DUF3584 PF12128.8 KKK24193.1 - 0.00072 17.2 10.1 0.00072 17.2 10.1 1.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3584) BLOC1_2 PF10046.9 KKK24193.1 - 0.0013 18.9 2.8 0.0013 18.9 2.8 3.1 3 1 1 4 4 4 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Fez1 PF06818.15 KKK24193.1 - 0.0096 16.4 19.8 0.094 13.2 18.4 2.7 2 1 0 2 2 2 1 Fez1 ABC_tran_CTD PF16326.5 KKK24193.1 - 0.0098 16.1 3.2 0.0098 16.1 3.2 4.8 2 1 2 4 4 4 1 ABC transporter C-terminal domain Baculo_PEP_C PF04513.12 KKK24193.1 - 0.013 15.5 7.3 0.022 14.8 0.7 2.8 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF948 PF06103.11 KKK24193.1 - 0.036 14.3 1.0 0.036 14.3 1.0 2.5 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Prefoldin PF02996.17 KKK24193.1 - 0.067 13.1 15.3 0.14 12.1 2.5 4.2 2 1 2 4 4 4 0 Prefoldin subunit NPV_P10 PF05531.12 KKK24193.1 - 0.096 13.2 3.6 6.3 7.3 0.3 3.6 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein APG6_N PF17675.1 KKK24193.1 - 0.77 10.3 25.3 2.7 8.5 12.1 3.2 2 1 1 3 3 3 0 Apg6 coiled-coil region Prefoldin_2 PF01920.20 KKK24193.1 - 0.83 9.6 20.1 0.25 11.3 2.6 4.3 2 1 1 3 3 3 0 Prefoldin subunit Syntaxin-6_N PF09177.11 KKK24193.1 - 0.89 10.1 11.5 5.4 7.6 2.9 3.8 2 1 1 3 3 3 0 Syntaxin 6, N-terminal DUF3552 PF12072.8 KKK24193.1 - 1.8 7.9 19.2 3.4 7.1 4.9 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) DUF1664 PF07889.12 KKK24193.1 - 2 8.5 9.4 0.29 11.2 2.4 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Med9 PF07544.13 KKK24193.1 - 2.1 8.5 10.0 0.79 9.9 1.1 3.9 3 1 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 DUF2721 PF11026.8 KKK24193.1 - 2.1 8.2 5.7 0.65 9.9 1.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) FlaC_arch PF05377.11 KKK24193.1 - 2.2 8.7 10.6 9.1 6.8 0.7 3.8 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) Atg14 PF10186.9 KKK24193.1 - 2.4 7.2 13.0 2.5 7.1 11.5 1.8 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 CENP-F_leu_zip PF10473.9 KKK24193.1 - 3 7.9 21.0 3.2 7.8 5.6 3.3 3 1 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 COG2 PF06148.11 KKK24193.1 - 3 7.9 11.4 0.62 10.1 0.7 2.7 3 0 0 3 3 2 0 COG (conserved oligomeric Golgi) complex component, COG2 YabA PF06156.13 KKK24193.1 - 3.2 8.5 13.8 6.8 7.4 0.7 3.6 3 1 0 3 3 3 0 Initiation control protein YabA LMBR1 PF04791.16 KKK24193.1 - 6.5 5.5 5.1 7.6 5.3 5.1 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein V_ATPase_I PF01496.19 KKK24193.1 - 6.9 4.5 8.9 19 3.0 9.0 1.7 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Tup_N PF08581.10 KKK24193.1 - 7.1 7.0 10.5 2.2 8.6 0.1 3.6 3 2 1 4 4 3 0 Tup N-terminal Tropomyosin_1 PF12718.7 KKK24193.1 - 7.2 6.8 21.5 3.3 7.9 17.9 2.1 2 0 0 2 2 2 0 Tropomyosin like SlyX PF04102.12 KKK24193.1 - 9.2 7.0 18.4 9 7.0 3.4 4.3 3 1 0 3 3 3 0 SlyX S4 PF01479.25 KKK24194.1 - 2.2e-12 46.5 0.8 2.2e-12 46.5 0.8 2.3 3 0 0 3 3 3 1 S4 domain Ribosomal_S4 PF00163.19 KKK24194.1 - 5.6e-06 27.2 0.2 1.1e-05 26.3 0.2 1.5 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain Zn_clus PF00172.18 KKK24195.1 - 1e-05 25.5 8.2 1.9e-05 24.7 8.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Myb_DNA-bind_6 PF13921.6 KKK24196.1 - 1.2e-16 60.7 0.0 2.4e-07 30.9 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KKK24196.1 - 9.6e-14 51.3 0.3 4e-07 30.1 0.1 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 KKK24196.1 - 0.0033 17.4 0.0 1.6 8.8 0.0 2.4 2 0 0 2 2 2 2 SLIDE FXR_C1 PF16096.5 KKK24196.1 - 0.24 11.6 4.4 2.9 8.2 0.0 3.6 3 1 0 3 3 3 0 Fragile X-related 1 protein C-terminal region 2 KH_dom-like PF14714.6 KKK24197.1 - 0.09 13.1 0.1 0.3 11.4 0.1 1.8 1 1 1 2 2 2 0 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal Aldedh PF00171.22 KKK24198.1 - 9.8e-155 515.6 0.2 1.1e-154 515.4 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Gln-synt_C PF00120.24 KKK24199.1 - 2e-62 211.2 0.0 6.4e-62 209.6 0.0 1.7 1 1 0 1 1 1 1 Glutamine synthetase, catalytic domain Amidohydro_2 PF04909.14 KKK24199.1 - 6.2e-15 55.7 0.0 1e-14 55.0 0.0 1.4 1 0 0 1 1 1 1 Amidohydrolase Annexin PF00191.20 KKK24200.1 - 2.3e-15 56.4 3.0 1.1e-05 25.4 0.1 4.4 4 0 0 4 4 4 4 Annexin DUF5127 PF17168.4 KKK24201.1 - 2e-84 282.9 5.1 3.1e-84 282.3 5.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) DUF4965 PF16335.5 KKK24201.1 - 1.8e-79 265.4 1.2 3.8e-79 264.4 1.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4965) DUF1793 PF08760.11 KKK24201.1 - 1.8e-64 217.2 3.7 2.1e-64 217.0 0.9 2.6 3 1 1 4 4 4 1 Domain of unknown function (DUF1793) DUF4964 PF16334.5 KKK24201.1 - 7.7e-07 28.6 0.1 2.9e-06 26.7 0.1 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4964) Vps62 PF06101.11 KKK24202.1 - 1.8e-10 39.8 2.3 3.2e-10 39.0 0.8 2.1 2 0 0 2 2 2 1 Vacuolar protein sorting-associated protein 62 Septin PF00735.18 KKK24203.1 - 2.1e-33 115.8 0.0 2.8e-13 49.8 0.0 3.1 3 0 0 3 3 3 3 Septin FtsK_SpoIIIE PF01580.18 KKK24203.1 - 0.002 17.5 0.0 0.0033 16.8 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family Dynamin_N PF00350.23 KKK24203.1 - 0.0025 17.9 0.5 0.01 15.9 0.0 2.3 3 0 0 3 3 3 1 Dynamin family MMR_HSR1 PF01926.23 KKK24203.1 - 0.0038 17.3 0.0 0.0095 16.0 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase G-alpha PF00503.20 KKK24203.1 - 0.051 12.7 0.0 0.13 11.4 0.0 1.6 2 0 0 2 2 2 0 G-protein alpha subunit AAA_16 PF13191.6 KKK24203.1 - 0.059 13.8 0.0 0.18 12.2 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain Pkinase PF00069.25 KKK24204.1 - 9.1e-22 77.7 0.0 8.9e-12 44.9 0.0 2.7 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KKK24204.1 - 2e-09 37.1 0.1 0.00079 18.8 0.0 3.3 4 0 0 4 4 4 2 Protein tyrosine kinase APH PF01636.23 KKK24204.1 - 0.025 14.5 0.0 0.4 10.6 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.6 KKK24204.1 - 0.26 10.6 0.0 4.9 6.4 0.0 2.5 3 0 0 3 3 3 0 Kinase-like DOPA_dioxygen PF08883.11 KKK24205.1 - 1.3e-40 137.9 0.0 1.6e-40 137.6 0.0 1.1 1 0 0 1 1 1 1 Dopa 4,5-dioxygenase family RRM_1 PF00076.22 KKK24206.1 - 6.7e-15 54.7 0.0 1.1e-14 54.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KKK24206.1 - 1.2e-05 25.0 0.0 2.3e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Occluded RNA-recognition motif FoP_duplication PF13865.6 KKK24206.1 - 2.5e-05 24.7 3.6 2.5e-05 24.7 3.6 2.9 3 0 0 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 RRM_7 PF16367.5 KKK24206.1 - 0.064 13.4 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif Snf7 PF03357.21 KKK24207.1 - 5.7e-20 71.6 15.1 5.7e-20 71.6 15.1 1.8 1 1 1 2 2 2 1 Snf7 DUF2408 PF10303.9 KKK24207.1 - 0.00048 20.7 5.5 0.00048 20.7 5.5 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2408) Gon7 PF08738.10 KKK24207.1 - 0.012 15.7 3.7 0.049 13.7 1.1 2.4 2 0 0 2 2 2 0 Gon7 family TPR_MLP1_2 PF07926.12 KKK24207.1 - 0.76 9.8 18.0 0.053 13.6 5.1 2.6 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein CS PF04969.16 KKK24208.1 - 1.5e-06 29.1 0.0 2.4e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 CS domain adh_short PF00106.25 KKK24213.1 - 2.5e-17 63.0 0.0 2.8e-17 62.8 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KKK24213.1 - 1.5e-11 44.3 0.0 1.7e-11 44.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KKK24213.1 - 3.7e-07 30.2 0.0 4.1e-07 30.1 0.0 1.0 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KKK24213.1 - 0.0089 15.2 0.0 0.01 15.0 0.0 1.0 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 KKK24213.1 - 0.0098 15.4 0.0 0.0098 15.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 KKK24213.1 - 0.029 14.6 0.0 0.032 14.5 0.0 1.1 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain 3Beta_HSD PF01073.19 KKK24213.1 - 0.089 11.8 0.0 0.11 11.5 0.0 1.0 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family TIR PF01582.20 KKK24213.1 - 0.17 11.6 0.0 0.18 11.6 0.0 1.2 1 0 0 1 1 1 0 TIR domain Methyltransf_2 PF00891.18 KKK24214.1 - 2.1e-20 72.9 0.0 3.1e-20 72.4 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_31 PF13847.6 KKK24214.1 - 0.00068 19.4 0.0 0.0013 18.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain HTH_AsnC-type PF13404.6 KKK24214.1 - 0.00087 19.1 0.0 0.0018 18.0 0.0 1.5 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain MTS PF05175.14 KKK24214.1 - 0.0058 16.2 0.0 0.013 15.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 KKK24214.1 - 0.011 16.4 0.0 0.031 15.0 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain HTH_28 PF13518.6 KKK24214.1 - 0.015 15.4 0.1 0.051 13.7 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain TetR_C_27 PF17935.1 KKK24214.1 - 0.073 13.1 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain HTH_24 PF13412.6 KKK24214.1 - 0.086 12.4 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Methyltransf_12 PF08242.12 KKK24214.1 - 0.17 12.6 0.0 0.35 11.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain IDO PF01231.18 KKK24215.1 - 2.9e-162 540.4 0.0 3.3e-162 540.2 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase Aminotran_5 PF00266.19 KKK24216.1 - 1.4e-41 142.7 0.0 1.6e-41 142.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Amidase PF01425.21 KKK24218.1 - 3.5e-97 326.2 0.0 1.2e-96 324.5 0.0 1.7 1 1 0 1 1 1 1 Amidase DUF4032 PF13224.6 KKK24218.1 - 0.14 12.0 0.0 0.28 11.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4032) DUF1815 PF08844.10 KKK24218.1 - 0.15 12.0 0.0 0.36 10.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1815) Arylsulfotran_2 PF14269.6 KKK24219.1 - 5.2e-43 147.5 0.1 7.7e-43 147.0 0.1 1.3 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 KKK24219.1 - 5.7e-14 51.8 0.1 3.2e-12 46.0 0.1 2.1 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) NlpE PF04170.12 KKK24219.1 - 0.086 13.8 0.3 30 5.6 0.0 2.9 2 1 1 3 3 3 0 NlpE N-terminal domain Methyltransf_28 PF02636.17 KKK24220.1 - 6.7e-41 140.6 0.0 9.3e-41 140.2 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase PRMT5 PF05185.16 KKK24220.1 - 0.16 11.8 0.0 0.28 11.0 0.0 1.4 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase Scm3 PF10384.9 KKK24221.1 - 5e-22 77.4 0.1 1.2e-21 76.1 0.1 1.7 1 0 0 1 1 1 1 Centromere protein Scm3 Myb_DNA-binding PF00249.31 KKK24221.1 - 6.5e-07 29.4 0.1 0.027 14.7 0.1 3.2 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KKK24221.1 - 4.7e-05 23.6 1.6 0.33 11.2 0.2 3.3 3 0 0 3 3 3 2 Myb-like DNA-binding domain PALP PF00291.25 KKK24222.1 - 5.4e-48 163.9 0.3 8e-47 160.1 0.3 2.0 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme adh_short PF00106.25 KKK24222.1 - 0.0044 16.5 0.0 0.014 14.8 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase APG6 PF04111.12 KKK24223.1 - 8.7e-74 247.3 0.0 1.3e-73 246.8 0.0 1.3 1 0 0 1 1 1 1 Apg6 BARA domain APG6_N PF17675.1 KKK24223.1 - 1.2e-38 132.6 8.8 1.9e-38 132.0 8.8 1.3 1 0 0 1 1 1 1 Apg6 coiled-coil region tRNA-synt_2c PF01411.19 KKK24223.1 - 0.017 13.6 0.4 0.024 13.1 0.4 1.1 1 0 0 1 1 1 0 tRNA synthetases class II (A) PTPlike_phytase PF14566.6 KKK24223.1 - 0.15 12.2 0.6 0.35 11.0 0.6 1.6 1 0 0 1 1 1 0 Inositol hexakisphosphate MbeD_MobD PF04899.12 KKK24223.1 - 2.7 8.2 5.6 29 4.9 0.7 2.8 3 0 0 3 3 3 0 MbeD/MobD like RNase_P_p30 PF01876.16 KKK24224.1 - 6.3e-64 215.4 0.0 8.2e-64 215.0 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit p30 Brix PF04427.18 KKK24225.1 - 4.6e-36 124.7 0.0 6.1e-36 124.3 0.0 1.2 1 0 0 1 1 1 1 Brix domain Tim17 PF02466.19 KKK24226.1 - 1.5e-14 54.3 0.4 2.9e-14 53.4 0.4 1.4 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Pkinase PF00069.25 KKK24227.1 - 2.2e-67 227.2 0.0 2.6e-67 227.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK24227.1 - 2.4e-19 69.6 0.0 3.4e-19 69.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KKK24227.1 - 4.2e-08 33.4 0.3 8.1e-05 22.7 0.1 2.6 2 1 1 3 3 3 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KKK24227.1 - 0.003 16.4 0.0 0.0052 15.6 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KKK24227.1 - 0.01 15.2 0.0 0.018 14.4 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.14 KKK24227.1 - 0.015 14.7 0.0 0.022 14.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 KKK24227.1 - 0.047 13.3 0.1 0.047 13.3 0.1 2.0 3 0 0 3 3 3 0 Choline/ethanolamine kinase tRNA-synt_1 PF00133.22 KKK24228.1 - 6.6e-224 744.6 0.0 7.3e-223 741.2 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KKK24228.1 - 1.1e-32 113.1 0.9 1.1e-32 113.1 0.9 2.0 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 KKK24228.1 - 1.7e-12 46.8 0.2 1.1e-05 24.4 0.0 4.6 5 1 0 5 5 5 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 KKK24228.1 - 6.2e-08 32.4 0.0 0.0001 21.9 0.0 2.6 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 KKK24228.1 - 0.025 13.9 0.0 0.2 11.0 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain Tox-SHH PF15652.6 KKK24228.1 - 0.12 13.3 1.7 0.54 11.2 0.7 2.7 2 0 0 2 2 2 0 HNH/Endo VII superfamily toxin with a SHH signature PepSY PF03413.19 KKK24228.1 - 3.2 8.4 7.8 2.2 8.9 0.0 3.4 3 0 0 3 3 3 0 Peptidase propeptide and YPEB domain Methyltransf_23 PF13489.6 KKK24229.1 - 2.4e-15 56.8 0.0 3.6e-15 56.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKK24229.1 - 7.8e-08 32.9 0.0 3.1e-07 31.0 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KKK24229.1 - 1.8e-05 25.4 0.0 5.4e-05 23.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KKK24229.1 - 7.1e-05 23.4 0.0 0.00032 21.3 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KKK24229.1 - 9.7e-05 22.2 0.1 0.00019 21.2 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 KKK24229.1 - 0.00038 20.6 0.0 0.00083 19.5 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase MTS PF05175.14 KKK24229.1 - 0.00093 18.8 0.0 0.0016 18.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 KKK24229.1 - 0.00098 18.6 0.0 0.0023 17.4 0.0 1.6 1 0 0 1 1 1 1 Putative methyltransferase PrmA PF06325.13 KKK24229.1 - 0.047 13.1 0.0 0.08 12.3 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.18 KKK24229.1 - 0.06 12.7 0.0 0.47 9.7 0.0 2.3 2 1 0 2 2 2 0 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.18 KKK24229.1 - 0.079 12.2 0.1 0.24 10.7 0.0 1.7 2 0 0 2 2 2 0 O-methyltransferase domain CMAS PF02353.20 KKK24229.1 - 0.095 12.0 0.0 0.18 11.0 0.0 1.4 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase p450 PF00067.22 KKK24230.1 - 3.8e-51 174.3 0.0 5.1e-51 173.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Acetyltransf_1 PF00583.25 KKK24231.1 - 5.2e-11 42.8 0.1 6.4e-11 42.5 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KKK24231.1 - 1.2e-07 31.7 0.2 2.2e-07 30.9 0.2 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KKK24231.1 - 5.4e-07 29.9 2.0 1.6e-06 28.4 1.9 1.7 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KKK24231.1 - 0.0044 17.0 0.1 0.0094 15.9 0.1 1.6 1 1 0 1 1 1 1 FR47-like protein Synapsin_N PF10581.9 KKK24231.1 - 0.1 12.6 0.1 0.22 11.5 0.1 1.5 1 0 0 1 1 1 0 Synapsin N-terminal ArAE_2_N PF10337.9 KKK24232.1 - 3.6e-119 398.9 2.6 3.6e-119 398.9 2.6 1.7 2 0 0 2 2 2 1 Putative ER transporter, 6TM, N-terminal ArAE_2 PF10334.9 KKK24232.1 - 3.2e-65 220.2 0.0 4.5e-63 213.1 0.0 2.4 2 0 0 2 2 2 2 Aromatic acid exporter family member 2 FUSC_2 PF13515.6 KKK24232.1 - 1.3e-09 38.2 15.3 1.3e-09 38.2 15.3 3.9 3 1 1 4 4 4 1 Fusaric acid resistance protein-like ALMT PF11744.8 KKK24232.1 - 0.0006 18.8 7.3 0.0006 18.8 7.3 1.7 2 0 0 2 2 2 1 Aluminium activated malate transporter DUF3592 PF12158.8 KKK24232.1 - 1 9.4 5.1 0.18 11.9 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3592) HERV-K_env_2 PF13804.6 KKK24233.1 - 0.071 12.9 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Retro-transcribing viruses envelope glycoprotein Fungal_trans PF04082.18 KKK24234.1 - 1.7e-07 30.5 0.7 3e-07 29.8 0.7 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain MARVEL PF01284.23 KKK24235.1 - 0.00042 20.4 0.9 0.005 16.9 0.1 2.4 2 0 0 2 2 2 1 Membrane-associating domain Otopetrin PF03189.13 KKK24235.1 - 0.027 13.3 1.6 0.04 12.7 1.6 1.2 1 0 0 1 1 1 0 Otopetrin DUF2474 PF10617.9 KKK24235.1 - 8.6 6.3 6.9 6 6.8 0.6 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2474) Sugar_tr PF00083.24 KKK24236.1 - 3.1e-77 260.4 17.6 3.8e-77 260.1 17.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKK24236.1 - 1.3e-26 93.4 16.9 1.9e-26 92.9 16.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Glyco_hydro_28 PF00295.17 KKK24237.1 - 2.7e-93 312.6 19.8 2.7e-93 312.6 19.8 2.2 2 0 0 2 2 2 1 Glycosyl hydrolases family 28 Pectinesterase PF01095.19 KKK24237.1 - 2e-33 115.4 2.6 1.1e-32 113.0 1.8 2.2 2 0 0 2 2 2 1 Pectinesterase Aa_trans PF01490.18 KKK24238.1 - 8.8e-24 84.0 24.6 1.9e-23 82.8 24.6 1.5 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein Glyco_hydro_43 PF04616.14 KKK24239.1 - 1.5e-102 342.8 0.9 3.5e-102 341.6 0.3 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 KKK24239.1 - 9.6e-45 152.8 0.0 1.4e-44 152.3 0.0 1.2 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain Ribonuclease PF00545.20 KKK24240.1 - 3.4e-07 30.9 0.3 4.7e-07 30.5 0.3 1.3 1 0 0 1 1 1 1 ribonuclease Aconitase PF00330.20 KKK24241.1 - 9.7e-73 245.7 0.0 5.3e-71 240.0 0.0 2.1 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KKK24241.1 - 2.4e-16 60.2 0.0 4.5e-16 59.4 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain MmgE_PrpD PF03972.14 KKK24242.1 - 4.9e-120 401.0 0.0 5.9e-120 400.8 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family MFS_1 PF07690.16 KKK24243.1 - 6.9e-20 71.3 55.4 1.2e-10 40.9 35.7 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily ABC_membrane PF00664.23 KKK24244.1 - 7.6e-52 176.6 41.4 2.5e-34 119.2 19.9 3.1 3 0 0 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.27 KKK24244.1 - 3.2e-49 166.9 0.0 1.7e-27 96.6 0.0 2.8 2 0 0 2 2 2 2 ABC transporter MMR_HSR1 PF01926.23 KKK24244.1 - 2.7e-07 30.6 0.5 0.017 15.2 0.1 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_21 PF13304.6 KKK24244.1 - 6.3e-07 29.5 2.1 0.088 12.6 0.4 3.6 2 2 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KKK24244.1 - 7.1e-07 28.9 0.7 0.56 9.6 0.0 3.6 2 1 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KKK24244.1 - 2.2e-06 28.2 0.6 0.08 13.3 0.0 3.3 3 1 0 3 3 2 2 AAA ATPase domain AAA_29 PF13555.6 KKK24244.1 - 2.8e-05 23.7 4.8 0.025 14.3 0.0 2.8 3 0 0 3 3 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KKK24244.1 - 5.7e-05 23.1 0.7 0.04 13.8 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase Dynamin_N PF00350.23 KKK24244.1 - 6.6e-05 23.0 1.2 0.012 15.7 0.0 2.6 2 0 0 2 2 2 1 Dynamin family AAA_23 PF13476.6 KKK24244.1 - 6.7e-05 23.5 0.1 0.35 11.3 0.1 2.5 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 KKK24244.1 - 0.00012 21.4 0.0 0.032 13.5 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin AAA_22 PF13401.6 KKK24244.1 - 0.00086 19.6 1.6 1.1 9.5 0.0 3.3 2 1 0 2 2 2 1 AAA domain DUF87 PF01935.17 KKK24244.1 - 0.0089 16.1 0.6 0.25 11.4 0.2 2.3 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_18 PF13238.6 KKK24244.1 - 0.019 15.5 0.2 4.5 7.8 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KKK24244.1 - 0.026 14.2 2.1 2.3 7.9 0.4 2.7 2 1 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 KKK24244.1 - 0.029 14.1 0.0 1.1 8.9 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein ATP_bind_1 PF03029.17 KKK24244.1 - 0.045 13.5 1.0 5 6.8 0.1 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA PF00004.29 KKK24244.1 - 0.047 14.1 0.1 2.4 8.6 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Ploopntkinase3 PF18751.1 KKK24244.1 - 0.063 13.2 0.1 12 5.7 0.0 2.4 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 AAA_15 PF13175.6 KKK24244.1 - 0.064 13.0 0.2 5.3 6.7 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_25 PF13481.6 KKK24244.1 - 0.07 12.7 0.6 2.3 7.7 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_27 PF13514.6 KKK24244.1 - 0.072 12.7 0.0 2.4 7.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 KKK24244.1 - 0.078 13.2 0.1 18 5.6 0.1 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase CDC45 PF02724.14 KKK24244.1 - 0.19 10.0 0.0 0.36 9.1 0.0 1.3 1 0 0 1 1 1 0 CDC45-like protein AAA_PrkA PF08298.11 KKK24244.1 - 0.2 10.6 0.1 0.94 8.3 0.0 2.0 2 0 0 2 2 2 0 PrkA AAA domain AAA_28 PF13521.6 KKK24244.1 - 0.84 9.9 3.2 1.9 8.7 0.1 2.7 2 0 0 2 2 2 0 AAA domain Phosphoesterase PF04185.14 KKK24245.1 - 2.6e-63 214.4 0.3 4e-63 213.8 0.3 1.3 1 0 0 1 1 1 1 Phosphoesterase family DUF1761 PF08570.10 KKK24247.1 - 6.3e-27 94.3 4.6 7.2e-27 94.1 4.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1761) Kinocilin PF15033.6 KKK24247.1 - 3.1 7.4 6.9 2.4 7.8 0.2 2.4 1 1 1 2 2 2 0 Kinocilin protein PRELI PF04707.14 KKK24248.1 - 4e-45 153.4 0.3 4.7e-45 153.2 0.3 1.0 1 0 0 1 1 1 1 PRELI-like family AhpC-TSA PF00578.21 KKK24249.1 - 1.5e-22 79.8 0.0 2.9e-22 78.9 0.0 1.5 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KKK24249.1 - 1.4e-11 44.3 0.0 1.9e-11 43.9 0.0 1.2 1 0 0 1 1 1 1 Redoxin DUF4677 PF15726.5 KKK24249.1 - 0.034 14.3 0.0 0.064 13.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4677) Flavoprotein PF02441.19 KKK24250.1 - 7.2e-42 142.8 0.0 9.6e-42 142.4 0.0 1.2 1 0 0 1 1 1 1 Flavoprotein ATPase_2 PF01637.18 KKK24250.1 - 0.11 12.4 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Glutaredoxin PF00462.24 KKK24251.1 - 6.6e-15 55.1 0.0 1.1e-14 54.4 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin zf-4CXXC_R1 PF10497.9 KKK24252.1 - 1.6e-08 34.7 12.3 1.6e-08 34.7 12.3 2.6 2 0 0 2 2 2 1 Zinc-finger domain of monoamine-oxidase A repressor R1 JmjC PF02373.22 KKK24252.1 - 3e-08 34.1 0.2 3.2e-07 30.8 0.2 2.5 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_2 PF07883.11 KKK24252.1 - 0.01 15.5 0.0 0.033 13.9 0.0 1.8 2 0 0 2 2 2 0 Cupin domain UbiA PF01040.18 KKK24253.1 - 5.2e-45 153.7 16.9 7e-45 153.3 16.9 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Ribosomal_L3 PF00297.22 KKK24254.1 - 1.2e-16 60.7 4.9 1.2e-13 50.8 1.5 2.1 1 1 1 2 2 2 2 Ribosomal protein L3 CTP_transf_like PF01467.26 KKK24256.1 - 7e-26 91.1 0.0 6e-23 81.6 0.0 2.7 3 0 0 3 3 3 2 Cytidylyltransferase-like zf-HC2 PF13490.6 KKK24257.1 - 0.19 12.0 0.7 0.31 11.3 0.7 1.4 1 0 0 1 1 1 0 Putative zinc-finger Coa1 PF08695.10 KKK24258.1 - 1.9e-31 108.2 0.1 2.5e-31 107.9 0.1 1.1 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 IF-2B PF01008.17 KKK24259.1 - 3.8e-74 249.4 0.3 4.4e-74 249.2 0.3 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family Nucleoporin_C PF03177.14 KKK24260.1 - 1.1e-175 585.9 7.7 1.3e-175 585.6 7.7 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.11 KKK24260.1 - 4.4e-75 253.1 0.0 6.7e-75 252.5 0.0 1.3 1 0 0 1 1 1 1 Nup133 N terminal like Acyl_transf_1 PF00698.21 KKK24261.1 - 3.9e-21 75.9 0.0 1.1e-14 54.7 0.0 2.1 2 0 0 2 2 2 2 Acyl transferase domain DUF4948 PF16306.5 KKK24261.1 - 0.014 15.2 0.0 0.035 13.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4948) Oxidored_q6 PF01058.22 KKK24262.1 - 3.9e-22 78.5 0.0 6.2e-22 77.8 0.0 1.3 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Mpp10 PF04006.12 KKK24263.1 - 5.4e-111 372.0 31.3 9.4e-111 371.2 31.3 1.3 1 0 0 1 1 1 1 Mpp10 protein Methyltransf_16 PF10294.9 KKK24264.1 - 9.3e-47 159.0 0.0 1.3e-46 158.6 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase Met_10 PF02475.16 KKK24264.1 - 0.043 13.5 0.0 0.4 10.4 0.0 1.9 2 0 0 2 2 2 0 Met-10+ like-protein AAA PF00004.29 KKK24303.1 - 1.8e-06 28.4 0.0 3.3e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) BCS1_N PF08740.11 KKK24303.1 - 0.00076 19.5 0.7 0.44 10.5 0.3 2.2 1 1 1 2 2 2 2 BCS1 N terminal AAA_16 PF13191.6 KKK24303.1 - 0.0012 19.2 0.1 0.004 17.5 0.0 1.8 2 1 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 KKK24303.1 - 0.0044 17.0 0.0 0.0075 16.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Polyoma_lg_T_C PF06431.11 KKK24303.1 - 0.025 13.5 0.0 0.034 13.0 0.0 1.1 1 0 0 1 1 1 0 Polyomavirus large T antigen C-terminus AAA_29 PF13555.6 KKK24303.1 - 0.028 14.1 0.0 0.051 13.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain PPV_E1_C PF00519.17 KKK24303.1 - 0.029 13.2 0.0 0.049 12.5 0.0 1.3 1 0 0 1 1 1 0 Papillomavirus helicase ABC_tran PF00005.27 KKK24303.1 - 0.033 14.7 0.0 0.065 13.7 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_22 PF13401.6 KKK24303.1 - 0.033 14.4 0.0 0.068 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.12 KKK24303.1 - 0.042 13.6 0.0 0.11 12.3 0.0 1.6 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_11 PF13086.6 KKK24303.1 - 0.061 13.1 0.0 0.089 12.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KKK24303.1 - 0.088 12.4 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KKK24303.1 - 0.093 13.1 0.0 0.17 12.2 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.6 KKK24303.1 - 0.12 13.0 0.0 0.54 10.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 KKK24303.1 - 0.12 12.6 0.0 2.4 8.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KKK24303.1 - 0.15 11.6 0.0 0.29 10.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region TIP49 PF06068.13 KKK24303.1 - 0.16 11.2 0.0 0.23 10.6 0.0 1.1 1 0 0 1 1 1 0 TIP49 P-loop domain ATPase PF06745.13 KKK24303.1 - 0.17 11.2 0.0 0.29 10.5 0.0 1.3 1 0 0 1 1 1 0 KaiC Pkinase PF00069.25 KKK24304.1 - 1.9e-58 197.9 0.0 1.7e-38 132.5 0.1 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KKK24304.1 - 3.5e-26 92.1 0.0 2.9e-20 72.6 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.24 KKK24304.1 - 3.6e-12 46.5 0.0 8.6e-12 45.2 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain Kinase-like PF14531.6 KKK24304.1 - 3.3e-08 33.2 0.5 1.9e-05 24.2 0.0 2.7 3 0 0 3 3 3 2 Kinase-like APH PF01636.23 KKK24304.1 - 4.7e-05 23.4 0.0 0.0033 17.4 0.2 2.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KKK24304.1 - 0.0035 16.7 0.0 0.0067 15.8 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KKK24304.1 - 0.0088 15.0 0.1 0.017 14.1 0.1 1.4 1 0 0 1 1 1 1 Haspin like kinase domain PAS PF00989.25 KKK24304.1 - 0.01 15.8 0.0 0.028 14.4 0.0 1.8 1 0 0 1 1 1 0 PAS fold FTA2 PF13095.6 KKK24304.1 - 0.022 14.4 0.0 7.5 6.1 0.0 2.5 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 PAS_4 PF08448.10 KKK24304.1 - 0.065 13.5 0.0 0.21 11.8 0.0 1.9 1 0 0 1 1 1 0 PAS fold Seadorna_VP7 PF07387.11 KKK24304.1 - 0.066 12.3 0.1 0.19 10.8 0.1 1.7 2 0 0 2 2 2 0 Seadornavirus VP7 PAS_9 PF13426.7 KKK24304.1 - 0.1 12.8 0.0 0.29 11.4 0.0 1.7 1 0 0 1 1 1 0 PAS domain Pkinase_C PF00433.24 KKK24304.1 - 3.7 8.3 6.5 7.5 7.3 2.8 3.4 2 1 0 2 2 2 0 Protein kinase C terminal domain C2 PF00168.30 KKK24310.1 - 6.7e-10 39.2 0.0 1.3e-09 38.2 0.0 1.5 1 0 0 1 1 1 1 C2 domain DHR10 PF18595.1 KKK24314.1 - 9.7 6.3 13.0 0.15 12.1 4.7 2.2 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain DnaJ PF00226.31 KKK24315.1 - 1.3e-26 92.5 2.1 2.1e-26 91.8 2.1 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_C PF01556.18 KKK24315.1 - 2.7e-25 89.2 0.0 4e-25 88.6 0.0 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.19 KKK24315.1 - 8.3e-15 54.9 14.0 1.3e-14 54.3 14.0 1.3 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 KKK24315.1 - 2e-06 27.7 6.3 0.0005 20.0 0.7 2.4 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 KKK24315.1 - 0.08 13.0 6.5 1.3 9.1 0.2 2.3 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Lar_restr_allev PF14354.6 KKK24315.1 - 4.5 7.7 10.2 2.9 8.3 1.7 3.4 1 1 2 3 3 3 0 Restriction alleviation protein Lar GRP PF07172.11 KKK24315.1 - 4.6 8.0 8.8 18 6.1 8.8 2.0 1 1 0 1 1 1 0 Glycine rich protein family zf-CSL PF05207.13 KKK24315.1 - 5 6.9 6.0 7 6.5 0.6 2.4 2 0 0 2 2 2 0 CSL zinc finger Malic_M PF03949.15 KKK24316.1 - 1.5e-91 306.3 0.0 1.9e-91 305.9 0.0 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 KKK24316.1 - 1.2e-46 158.9 0.0 2.6e-36 125.1 0.0 2.3 1 1 1 2 2 2 2 Malic enzyme, N-terminal domain DUF4449 PF14613.6 KKK24317.1 - 0.00012 22.2 0.1 0.00012 22.2 0.1 3.4 3 1 1 4 4 4 1 Protein of unknown function (DUF4449) Tricorn_C1 PF14684.6 KKK24317.1 - 0.00054 20.0 0.0 0.0032 17.5 0.1 2.4 2 0 0 2 2 2 1 Tricorn protease C1 domain AbiH PF14253.6 KKK24317.1 - 0.24 11.2 0.5 0.45 10.4 0.5 1.5 1 0 0 1 1 1 0 Bacteriophage abortive infection AbiH Gp-FAR-1 PF05823.12 KKK24317.1 - 1.5 9.1 4.0 5.8 7.3 0.3 2.6 1 1 1 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Com_YlbF PF06133.11 KKK24317.1 - 3 8.5 6.6 12 6.5 1.1 3.2 1 1 2 3 3 3 0 Control of competence regulator ComK, YlbF/YmcA 3-HAO PF06052.12 KKK24319.1 - 3.7e-34 117.5 0.0 6.5e-34 116.8 0.0 1.3 2 0 0 2 2 2 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.11 KKK24319.1 - 0.00075 19.2 0.0 0.0014 18.3 0.0 1.4 1 0 0 1 1 1 1 Cupin domain DZR PF12773.7 KKK24319.1 - 0.00093 19.2 0.9 0.0019 18.2 0.9 1.5 1 0 0 1 1 1 1 Double zinc ribbon Cupin_1 PF00190.22 KKK24319.1 - 0.022 14.4 0.0 0.035 13.7 0.0 1.2 1 0 0 1 1 1 0 Cupin Nudix_N_2 PF14803.6 KKK24319.1 - 0.027 14.4 1.2 5 7.1 0.1 2.6 2 0 0 2 2 2 0 Nudix N-terminal Plant_tran PF04827.14 KKK24319.1 - 0.061 12.9 0.1 0.09 12.4 0.1 1.2 1 0 0 1 1 1 0 Plant transposon protein zf-3CxxC PF13695.6 KKK24319.1 - 0.093 13.2 0.5 0.15 12.5 0.5 1.3 1 0 0 1 1 1 0 Zinc-binding domain zf-RRN7 PF11781.8 KKK24319.1 - 0.22 11.2 5.5 5.3 6.8 0.3 2.8 3 0 0 3 3 3 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 TF_Zn_Ribbon PF08271.12 KKK24319.1 - 0.59 9.7 3.1 4 7.0 0.1 2.8 2 1 0 2 2 2 0 TFIIB zinc-binding Zn-ribbon_8 PF09723.10 KKK24319.1 - 1.5 9.0 6.0 0.87 9.8 0.3 2.8 2 1 1 3 3 3 0 Zinc ribbon domain RTC_insert PF05189.13 KKK24320.1 - 3.6e-29 101.3 0.0 7.1e-29 100.4 0.0 1.5 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain RTC PF01137.21 KKK24320.1 - 4.9e-26 91.3 0.0 6e-26 91.0 0.0 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase Glyco_hydro_43 PF04616.14 KKK24321.1 - 9.6e-27 94.0 5.3 4.2e-18 65.7 1.8 2.7 2 1 0 2 2 2 2 Glycosyl hydrolases family 43 Fungal_trans PF04082.18 KKK24322.1 - 5.5e-14 51.8 0.0 9.2e-14 51.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK24322.1 - 4e-06 26.8 13.5 8.4e-06 25.8 13.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAP2_3 PF14378.6 KKK24323.1 - 2.9e-33 115.2 10.4 1e-15 58.0 0.1 3.4 3 0 0 3 3 3 3 PAP2 superfamily PAP2 PF01569.21 KKK24323.1 - 0.0099 15.6 2.3 0.024 14.4 1.0 2.2 1 1 1 2 2 2 1 PAP2 superfamily PWWP PF00855.17 KKK24324.1 - 2.2e-05 24.7 0.3 2.2e-05 24.7 0.3 3.1 2 1 0 2 2 2 1 PWWP domain Med26 PF08711.11 KKK24324.1 - 0.00032 20.7 0.2 0.00083 19.3 0.2 1.8 1 0 0 1 1 1 1 TFIIS helical bundle-like domain SpoIIE PF07228.12 KKK24325.1 - 3.5e-11 43.4 0.2 7.6e-10 39.0 0.1 2.2 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.21 KKK24325.1 - 2.8e-07 30.4 0.0 0.013 15.2 0.0 2.3 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 KKK24325.1 - 1.4e-06 28.1 1.0 3.3e-06 26.9 1.0 1.6 1 1 0 1 1 1 1 Protein phosphatase 2C HSCB_C PF07743.13 KKK24326.1 - 5.9e-21 74.7 0.0 1.5e-19 70.2 0.0 2.1 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.31 KKK24326.1 - 1.8e-05 24.8 0.1 3.7e-05 23.8 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain Med21 PF11221.8 KKK24326.1 - 5.6 7.2 5.5 6.3 7.1 3.3 2.0 1 1 1 2 2 2 0 Subunit 21 of Mediator complex WD40 PF00400.32 KKK24327.1 - 7.6e-36 121.5 22.0 6.2e-07 30.0 2.6 7.5 7 1 0 7 7 7 6 WD domain, G-beta repeat PRP4 PF08799.11 KKK24327.1 - 1.3e-15 56.7 5.1 2.3e-15 55.8 5.1 1.4 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like ANAPC4_WD40 PF12894.7 KKK24327.1 - 2.7e-11 43.6 0.1 0.017 15.4 0.0 5.4 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KKK24327.1 - 0.0081 15.5 0.0 0.13 11.6 0.0 2.6 3 0 0 3 3 3 1 WD40-like domain Ge1_WD40 PF16529.5 KKK24327.1 - 0.018 14.0 0.0 3 6.7 0.0 3.3 3 1 1 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Nop53 PF07767.11 KKK24327.1 - 0.13 11.7 6.5 0.19 11.1 6.5 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) PRTP PF01366.18 KKK24327.1 - 0.32 9.0 0.8 0.45 8.5 0.8 1.1 1 0 0 1 1 1 0 Herpesvirus processing and transport protein SLAC1 PF03595.17 KKK24328.1 - 3.2e-82 276.4 35.4 3.7e-82 276.2 35.4 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel BTB PF00651.31 KKK24329.1 - 0.055 13.7 0.2 4.1 7.7 0.0 2.6 3 0 0 3 3 3 0 BTB/POZ domain Neisseria_TspB PF05616.13 KKK24329.1 - 6 5.2 11.4 9.6 4.6 11.4 1.2 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein SnoaL_2 PF12680.7 KKK24330.1 - 7.9e-07 29.7 0.0 9.8e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain MFS_1 PF07690.16 KKK24331.1 - 3.3e-28 98.6 27.8 4.5e-28 98.2 27.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Pkinase PF00069.25 KKK24332.1 - 2.7e-33 115.5 0.0 2e-19 70.0 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KKK24332.1 - 2.9e-13 49.7 0.0 4.1e-12 45.9 0.0 2.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KKK24332.1 - 0.0077 15.6 0.0 2 7.6 0.0 2.3 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 KKK24332.1 - 0.1 12.5 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family CAP_GLY PF01302.25 KKK24333.1 - 2.3e-15 56.3 0.8 4.8e-15 55.3 0.8 1.6 1 0 0 1 1 1 1 CAP-Gly domain CLIP1_ZNF PF16641.5 KKK24333.1 - 1.1e-10 41.1 9.4 4.8e-05 23.1 1.0 2.6 2 0 0 2 2 2 2 CLIP1 zinc knuckle TMF_DNA_bd PF12329.8 KKK24333.1 - 0.00014 21.8 25.4 0.34 11.0 3.7 5.1 5 0 0 5 5 5 2 TATA element modulatory factor 1 DNA binding FAM76 PF16046.5 KKK24333.1 - 0.0029 17.0 1.1 0.0029 17.0 1.1 3.2 1 1 2 3 3 3 1 FAM76 protein Seryl_tRNA_N PF02403.22 KKK24333.1 - 0.017 15.4 8.9 0.64 10.3 2.0 3.6 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain NPV_P10 PF05531.12 KKK24333.1 - 0.024 15.1 9.9 1.3 9.5 0.3 3.5 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein SKA1 PF07160.12 KKK24333.1 - 0.025 14.5 7.6 1.5 8.6 1.4 3.2 3 0 0 3 3 3 0 Spindle and kinetochore-associated protein 1 Phage_GP20 PF06810.11 KKK24333.1 - 0.026 14.4 19.7 0.15 11.9 1.4 3.9 4 0 0 4 4 4 0 Phage minor structural protein GP20 SHE3 PF17078.5 KKK24333.1 - 0.13 12.0 9.3 4.1 7.1 0.0 2.5 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 YajC PF02699.15 KKK24333.1 - 0.13 12.2 0.9 0.36 10.7 0.1 2.1 2 0 0 2 2 2 0 Preprotein translocase subunit BLOC1_2 PF10046.9 KKK24333.1 - 0.16 12.3 17.1 0.14 12.5 2.9 3.9 4 0 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Med28 PF11594.8 KKK24333.1 - 0.43 10.6 3.0 1.2 9.2 0.1 2.7 2 1 1 3 3 3 0 Mediator complex subunit 28 End3 PF12761.7 KKK24333.1 - 0.46 10.6 13.8 4.8 7.3 0.1 3.3 3 0 0 3 3 3 0 Actin cytoskeleton-regulatory complex protein END3 EzrA PF06160.12 KKK24333.1 - 0.7 8.0 21.5 0.034 12.3 14.5 2.1 2 1 0 2 2 2 0 Septation ring formation regulator, EzrA V_ATPase_I PF01496.19 KKK24333.1 - 1.4 6.8 7.4 20 2.9 6.5 2.1 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Fez1 PF06818.15 KKK24333.1 - 1.5 9.2 31.5 57 4.1 2.1 3.4 1 1 0 2 2 2 0 Fez1 zf_PR_Knuckle PF18445.1 KKK24333.1 - 2 8.3 4.8 2.9 7.8 0.4 2.3 2 0 0 2 2 2 0 PR zinc knuckle motif HemX PF04375.14 KKK24333.1 - 3.4 6.9 18.5 0.6 9.3 3.5 3.1 2 1 0 3 3 3 0 HemX, putative uroporphyrinogen-III C-methyltransferase DUF812 PF05667.11 KKK24333.1 - 3.9 6.3 23.0 0.034 13.0 12.3 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF812) TPR_MLP1_2 PF07926.12 KKK24333.1 - 4.1 7.5 31.7 0.11 12.6 11.0 3.3 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein AAA_13 PF13166.6 KKK24333.1 - 4.4 5.8 15.7 16 4.0 13.1 2.2 1 1 1 2 2 2 0 AAA domain Spc7 PF08317.11 KKK24333.1 - 5.1 5.9 30.5 2.6 6.8 9.4 3.1 1 1 2 3 3 3 0 Spc7 kinetochore protein DUF241 PF03087.14 KKK24333.1 - 5.4 6.8 9.7 1.6 8.6 5.6 2.2 2 1 0 2 2 2 0 Arabidopsis protein of unknown function DUF1664 PF07889.12 KKK24333.1 - 5.7 7.0 14.5 2.2 8.3 2.2 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) DUF4407 PF14362.6 KKK24333.1 - 6.1 6.1 16.3 30 3.8 12.5 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Yip1 PF04893.17 KKK24334.1 - 1.9e-14 53.8 15.9 2.7e-14 53.3 15.9 1.3 1 0 0 1 1 1 1 Yip1 domain YIF1 PF03878.15 KKK24334.1 - 0.094 12.2 3.3 0.13 11.8 1.1 2.1 1 1 1 2 2 2 0 YIF1 Fcf1 PF04900.12 KKK24338.1 - 1.3e-33 115.3 1.4 5.2e-33 113.4 0.1 1.9 2 0 0 2 2 2 1 Fcf1 PIN_9 PF18477.1 KKK24338.1 - 4.3e-09 36.7 0.2 1e-08 35.5 0.0 1.6 2 0 0 2 2 2 1 PIN like domain DAO PF01266.24 KKK24339.1 - 3.2e-30 105.9 0.1 3.7e-30 105.7 0.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Sugar_tr PF00083.24 KKK24340.1 - 3e-105 352.7 20.1 3.5e-105 352.5 20.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKK24340.1 - 6.8e-19 68.0 35.7 2.9e-17 62.7 22.3 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Phage_holin_2_3 PF16080.5 KKK24340.1 - 1.6 8.5 5.8 1.3 8.8 0.3 3.2 3 0 0 3 3 3 0 Bacteriophage holin family HP1 Fungal_trans_2 PF11951.8 KKK24341.1 - 2.2e-08 33.4 1.1 3e-08 32.9 1.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK24341.1 - 4.9e-06 26.6 10.6 1.1e-05 25.4 10.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Claudin_2 PF13903.6 KKK24342.1 - 0.0082 15.9 1.2 0.0082 15.9 1.2 2.4 1 1 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction COX7C PF02935.16 KKK24342.1 - 0.023 15.0 0.6 2 8.7 0.1 2.9 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VIIc RTA1 PF04479.13 KKK24342.1 - 0.03 13.9 8.8 0.031 13.9 7.8 1.6 1 1 0 1 1 1 0 RTA1 like protein K1 PF02960.14 KKK24342.1 - 0.044 13.9 0.1 0.085 13.0 0.1 1.4 1 0 0 1 1 1 0 K1 glycoprotein CPBP PF02517.16 KKK24342.1 - 6.3 7.2 10.9 1.3e+02 3.0 10.9 2.7 1 1 0 1 1 1 0 CPBP intramembrane metalloprotease PspC PF04024.12 KKK24342.1 - 9.4 6.2 18.8 1 9.2 1.9 3.8 3 2 0 3 3 3 0 PspC domain GFO_IDH_MocA PF01408.22 KKK24343.1 - 2.5e-25 89.6 0.8 3.6e-24 85.9 0.3 2.2 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 KKK24343.1 - 1e-05 26.1 0.4 2.5e-05 24.9 0.2 1.8 2 0 0 2 2 2 1 Homoserine dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.22 KKK24344.1 - 4.2e-18 66.3 0.0 6.9e-18 65.6 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Sugar_tr PF00083.24 KKK24345.1 - 1.5e-40 139.5 6.1 1.8e-40 139.2 6.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKK24345.1 - 4.8e-18 65.2 12.1 5.7e-18 65.0 12.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Mg_trans_NIPA PF05653.14 KKK24378.1 - 1.2e-55 188.8 7.9 3.1e-55 187.4 6.9 1.9 2 0 0 2 2 2 1 Magnesium transporter NIPA EamA PF00892.20 KKK24378.1 - 0.00032 20.9 0.5 0.00032 20.9 0.5 2.6 2 0 0 2 2 2 1 EamA-like transporter family BTP PF05232.12 KKK24378.1 - 2.3 8.3 8.0 3.1 7.9 1.0 2.6 2 0 0 2 2 2 0 Chlorhexidine efflux transporter AAA PF00004.29 KKK24379.1 - 6.1e-41 139.9 0.0 1.2e-40 139.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KKK24379.1 - 1.8e-10 40.4 0.5 3.3e-10 39.6 0.5 1.4 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 KKK24379.1 - 1.3e-09 37.8 0.1 2.4e-09 37.0 0.1 1.5 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_22 PF13401.6 KKK24379.1 - 2.2e-06 28.0 0.2 0.02 15.1 0.1 2.5 1 1 1 2 2 2 2 AAA domain AAA_2 PF07724.14 KKK24379.1 - 1.1e-05 25.6 0.0 2.4e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 KKK24379.1 - 1.2e-05 24.6 0.0 2e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.14 KKK24379.1 - 4e-05 23.6 0.0 0.00011 22.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KKK24379.1 - 0.00027 21.4 0.3 0.0036 17.7 0.3 2.2 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 KKK24379.1 - 0.00066 19.5 0.0 0.0013 18.5 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 KKK24379.1 - 0.0028 17.9 0.3 0.0073 16.6 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_18 PF13238.6 KKK24379.1 - 0.0041 17.7 0.2 0.011 16.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KKK24379.1 - 0.014 15.5 0.0 0.031 14.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 KKK24379.1 - 0.016 14.7 0.6 0.51 9.7 0.1 2.2 2 0 0 2 2 2 0 PhoH-like protein IstB_IS21 PF01695.17 KKK24379.1 - 0.017 14.9 0.0 0.038 13.7 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_14 PF13173.6 KKK24379.1 - 0.02 14.9 0.0 0.04 14.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 KKK24379.1 - 0.02 14.7 0.0 0.04 13.8 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.13 KKK24379.1 - 0.029 13.6 0.7 0.064 12.5 0.1 1.8 2 1 0 2 2 2 0 TIP49 P-loop domain ATPase PF06745.13 KKK24379.1 - 0.034 13.5 0.2 0.56 9.5 0.1 2.2 1 1 0 2 2 2 0 KaiC NACHT PF05729.12 KKK24379.1 - 0.037 14.0 0.2 0.65 9.9 0.1 2.3 1 1 0 2 2 2 0 NACHT domain RNA_helicase PF00910.22 KKK24379.1 - 0.046 14.1 0.0 0.1 13.0 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Mg_chelatase PF01078.21 KKK24379.1 - 0.06 12.7 0.1 0.12 11.7 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.12 KKK24379.1 - 0.067 12.5 0.0 0.18 11.0 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin AAA_25 PF13481.6 KKK24379.1 - 0.074 12.6 1.5 0.58 9.7 0.4 2.4 1 1 0 2 2 2 0 AAA domain Prot_ATP_OB_N PF17758.1 KKK24379.1 - 0.14 11.8 0.5 1 9.0 0.0 2.5 2 0 0 2 2 2 0 Proteasomal ATPase OB N-terminal domain AAA_24 PF13479.6 KKK24379.1 - 0.17 11.6 2.0 0.3 10.8 0.3 2.2 2 1 0 2 2 2 0 AAA domain DUF2075 PF09848.9 KKK24379.1 - 0.18 11.0 0.0 0.27 10.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DUF2985 PF11204.8 KKK24380.1 - 4.7e-22 77.9 3.6 8.6e-22 77.1 3.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) Peptidase_S49_N PF08496.10 KKK24380.1 - 0.066 13.3 1.0 0.14 12.2 1.0 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Rootletin PF15035.6 KKK24381.1 - 0.042 13.9 3.5 0.14 12.2 3.6 1.8 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion YabA PF06156.13 KKK24381.1 - 2.2 9.0 4.0 33 5.2 0.3 2.5 2 0 0 2 2 2 0 Initiation control protein YabA Glyco_hydro_3 PF00933.21 KKK24382.1 - 1.6e-58 198.6 0.0 2.1e-58 198.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 KKK24382.1 - 3.7e-54 183.8 0.0 6e-54 183.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 KKK24382.1 - 1.1e-20 73.5 1.6 1.1e-20 73.5 1.6 2.0 2 0 0 2 2 2 1 Fibronectin type III-like domain DUF5441 PF17513.2 KKK24382.1 - 0.0024 17.6 0.1 0.043 13.6 0.1 2.3 2 0 0 2 2 2 1 Family of unknown function (DUF5441) Sugar-bind PF04198.13 KKK24382.1 - 0.13 11.3 0.0 0.24 10.5 0.0 1.3 1 0 0 1 1 1 0 Putative sugar-binding domain ArfGap PF01412.18 KKK24383.1 - 2.7e-29 101.6 0.0 4.5e-29 100.9 0.0 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Epimerase PF01370.21 KKK24384.1 - 2.6e-11 43.4 0.1 6.4e-05 22.5 0.2 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KKK24384.1 - 8.2e-09 35.4 0.1 1.2e-08 34.8 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KKK24384.1 - 1.3e-08 35.0 0.1 1.8e-08 34.5 0.1 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 KKK24384.1 - 2.6e-06 27.9 0.1 4.2e-06 27.2 0.1 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 KKK24384.1 - 0.00096 18.2 0.0 0.0036 16.3 0.0 1.7 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 KKK24384.1 - 0.004 16.3 0.1 0.0056 15.9 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Sacchrp_dh_NADP PF03435.18 KKK24384.1 - 0.0043 17.3 0.0 0.011 15.9 0.1 1.7 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_4 PF07993.12 KKK24384.1 - 0.0045 16.2 0.0 0.023 13.9 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein Shikimate_DH PF01488.20 KKK24384.1 - 0.031 14.3 0.0 0.095 12.8 0.0 1.9 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase Toprim PF01751.22 KKK24384.1 - 0.17 12.1 0.1 0.75 10.0 0.1 2.0 1 1 1 2 2 2 0 Toprim domain THOC2_N PF16134.5 KKK24385.1 - 7.8e-253 840.8 1.9 2.3e-251 835.9 0.0 2.8 3 0 0 3 3 3 1 THO complex subunit 2 N-terminus Tho2 PF11262.8 KKK24385.1 - 1.3e-105 352.9 0.0 2.6e-105 351.9 0.0 1.5 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.8 KKK24385.1 - 2.2e-14 53.3 0.3 7.8e-14 51.5 0.1 2.1 2 0 0 2 2 2 1 Transcription- and export-related complex subunit Ant_C PF05586.11 KKK24385.1 - 0.071 13.7 0.1 13 6.5 0.0 2.9 2 0 0 2 2 2 0 Anthrax receptor C-terminus region WD40 PF00400.32 KKK24386.1 - 5.2e-14 52.4 15.2 0.00014 22.5 0.9 5.4 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKK24386.1 - 0.0008 19.7 0.1 0.29 11.5 0.0 3.0 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nop14 PF04147.12 KKK24386.1 - 0.27 9.4 10.9 0.35 9.0 10.9 1.1 1 0 0 1 1 1 0 Nop14-like family TFIIF_alpha PF05793.12 KKK24386.1 - 0.33 9.5 14.7 0.51 8.9 14.7 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) UQ_con PF00179.26 KKK24387.1 - 1.4e-43 148.0 0.0 1.7e-43 147.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.10 KKK24387.1 - 1.9e-07 30.8 1.2 3.8e-06 26.6 0.0 2.3 1 1 1 2 2 2 1 Fungal ubiquitin-associated domain Prok-E2_B PF14461.6 KKK24387.1 - 0.00059 19.6 0.0 0.00093 18.9 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 KKK24387.1 - 0.013 15.7 0.0 0.03 14.6 0.0 1.6 1 0 0 1 1 1 0 RWD domain DUF1421 PF07223.11 KKK24387.1 - 0.062 13.1 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 UBA-like domain (DUF1421) SnAPC_2_like PF11035.8 KKK24387.1 - 0.074 13.2 0.0 0.089 12.9 0.0 1.1 1 0 0 1 1 1 0 Small nuclear RNA activating complex subunit 2, SNAP190 Myb RRM_1 PF00076.22 KKK24388.1 - 2.2e-30 104.3 0.2 4.1e-15 55.4 0.0 3.2 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KKK24388.1 - 0.00019 21.5 0.0 0.039 14.1 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif RRM_5 PF13893.6 KKK24388.1 - 0.00049 19.7 0.0 1.1 8.8 0.0 3.1 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 KKK24388.1 - 0.0083 16.4 0.3 5.2 7.3 0.0 3.3 2 2 1 3 3 3 2 Cytosolic domain of 10TM putative phosphate transporter RRM_Rrp7 PF17799.1 KKK24388.1 - 0.21 11.4 0.0 1.5 8.6 0.0 2.0 2 0 0 2 2 2 0 Rrp7 RRM-like N-terminal domain FXMRP1_C_core PF12235.8 KKK24388.1 - 0.79 10.4 12.7 0.2 12.3 9.1 1.8 2 0 0 2 2 2 0 Fragile X-related 1 protein core C terminal Cyclin_C_2 PF16899.5 KKK24389.1 - 5.6e-39 132.7 0.1 7.4e-36 122.7 0.0 2.4 2 0 0 2 2 2 2 Cyclin C-terminal domain Cyclin_N PF00134.23 KKK24389.1 - 8.3e-07 28.8 0.0 2.1e-06 27.5 0.0 1.7 1 0 0 1 1 1 1 Cyclin, N-terminal domain GTP_EFTU PF00009.27 KKK24390.1 - 2.8e-56 190.1 0.0 4.7e-56 189.4 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.6 KKK24390.1 - 4.3e-26 90.8 0.0 9.4e-26 89.7 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 KKK24390.1 - 1.8e-15 56.7 0.0 9.3e-08 32.0 0.0 2.5 2 0 0 2 2 2 2 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KKK24390.1 - 7.8e-06 26.2 0.0 1.5e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 KKK24390.1 - 0.00079 19.3 0.0 0.0018 18.1 0.0 1.5 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain EFG_IV PF03764.18 KKK24390.1 - 0.082 12.7 0.0 0.22 11.3 0.0 1.7 1 0 0 1 1 1 0 Elongation factor G, domain IV Vps5 PF09325.10 KKK24391.1 - 2.3e-13 50.3 1.3 3.5e-13 49.6 1.3 1.2 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.24 KKK24391.1 - 1.6e-09 37.7 0.0 3.3e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 PX domain VASt PF16016.5 KKK24392.1 - 8.2e-36 123.7 0.0 1.4e-35 123.0 0.0 1.4 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 KKK24392.1 - 1.7e-22 79.5 0.0 3e-22 78.7 0.0 1.4 1 0 0 1 1 1 1 GRAM domain RNB PF00773.19 KKK24403.1 - 2.9e-83 279.9 0.0 6.3e-83 278.8 0.0 1.6 1 0 0 1 1 1 1 RNB domain OB_Dis3 PF17849.1 KKK24403.1 - 1.2e-26 92.5 0.0 3.5e-26 91.0 0.0 1.9 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) Dis3l2_C_term PF17877.1 KKK24403.1 - 4.5e-26 91.0 0.0 1.8e-25 89.0 0.0 2.1 2 0 0 2 2 2 1 DIS3-like exonuclease 2 C terminal Rrp44_CSD1 PF17216.3 KKK24403.1 - 1.5e-05 24.8 0.0 3.5e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Rrp44-like cold shock domain CSD2 PF17876.1 KKK24403.1 - 4.3e-05 23.6 0.0 0.023 14.8 0.0 2.7 2 0 0 2 2 2 2 Cold shock domain Rrp44_S1 PF17215.3 KKK24403.1 - 0.17 11.8 0.0 0.62 10.1 0.0 2.0 1 0 0 1 1 1 0 S1 domain GLE1 PF07817.13 KKK24404.1 - 3.4e-49 167.3 0.0 8.1e-49 166.1 0.0 1.6 1 0 0 1 1 1 1 GLE1-like protein Borrelia_P83 PF05262.11 KKK24404.1 - 8.5 4.7 40.4 12 4.2 40.4 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein MAM33 PF02330.16 KKK24407.1 - 2.7e-71 239.9 1.6 4.6e-71 239.1 1.6 1.4 1 0 0 1 1 1 1 Mitochondrial glycoprotein Tma16 PF11176.8 KKK24407.1 - 1.5e-52 177.4 0.0 3.5e-52 176.2 0.0 1.6 1 0 0 1 1 1 1 Translation machinery-associated protein 16 NPV_P10 PF05531.12 KKK24407.1 - 0.1 13.1 0.2 0.4 11.2 0.1 2.0 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein XPG_I PF00867.18 KKK24408.1 - 6.6e-24 84.1 0.2 1.5e-23 82.9 0.2 1.7 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 KKK24408.1 - 2.2e-23 82.6 0.0 5.7e-23 81.3 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.7 KKK24408.1 - 1.5e-05 24.7 0.1 2.4e-05 23.9 0.1 1.3 1 0 0 1 1 1 1 XPG domain containing TPR_2 PF07719.17 KKK24408.1 - 0.14 12.4 0.0 0.4 10.9 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat HTH_13 PF11972.8 KKK24408.1 - 0.16 12.1 0.2 9 6.5 0.0 2.8 3 0 0 3 3 3 0 HTH DNA binding domain 5_3_exonuc PF01367.20 KKK24408.1 - 0.16 12.5 0.0 0.46 11.1 0.0 1.7 1 0 0 1 1 1 0 5'-3' exonuclease, C-terminal SAM fold Fig1 PF12351.8 KKK24409.1 - 2.3e-46 158.1 12.5 6.5e-31 107.7 0.0 3.0 2 1 1 3 3 3 2 Ca2+ regulator and membrane fusion protein Fig1 SAM_adeno_trans PF01887.16 KKK24409.1 - 0.023 14.1 0.2 0.034 13.6 0.2 1.1 1 0 0 1 1 1 0 S-adenosyl-l-methionine hydroxide adenosyltransferase SUR7 PF06687.12 KKK24409.1 - 0.039 13.6 13.3 0.41 10.2 13.3 2.1 1 1 0 1 1 1 0 SUR7/PalI family ODV-E18 PF10717.9 KKK24409.1 - 0.054 13.4 1.0 0.054 13.4 1.0 2.7 3 0 0 3 3 3 0 Occlusion-derived virus envelope protein ODV-E18 DUF2207 PF09972.9 KKK24409.1 - 2.6 6.7 11.8 1.1 7.9 4.9 2.3 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) DUF4014 PF13198.6 KKK24409.1 - 7.2 7.1 9.4 0.67 10.4 3.5 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF4014) COesterase PF00135.28 KKK24410.1 - 2.2e-76 257.8 0.0 6.7e-76 256.2 0.0 1.7 2 1 0 2 2 2 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KKK24410.1 - 1.7e-11 44.4 0.0 5.8e-11 42.6 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KKK24410.1 - 0.053 13.0 0.0 0.098 12.1 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family DNA_primase_S PF01896.19 KKK24411.1 - 3.2e-61 206.4 0.0 4.4e-61 206.0 0.0 1.2 1 0 0 1 1 1 1 DNA primase small subunit Ras PF00071.22 KKK24436.1 - 5.4e-60 201.7 0.2 6.4e-60 201.4 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KKK24436.1 - 1.8e-20 73.3 0.0 2.7e-20 72.8 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKK24436.1 - 1.5e-08 34.3 0.0 1.7e-08 34.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KKK24436.1 - 1.8e-06 27.6 0.1 1e-05 25.2 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KKK24436.1 - 6.1e-05 23.0 0.7 0.18 11.7 0.0 2.3 1 1 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 KKK24436.1 - 0.0021 17.6 0.0 0.0034 16.9 0.0 1.3 1 1 0 1 1 1 1 Ferrous iron transport protein B MMR_HSR1 PF01926.23 KKK24436.1 - 0.0021 18.1 0.0 0.0033 17.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase MMR_HSR1_Xtn PF16897.5 KKK24436.1 - 0.0057 16.7 0.0 0.011 15.7 0.0 1.6 1 1 0 1 1 1 1 C-terminal region of MMR_HSR1 domain ATP_bind_1 PF03029.17 KKK24436.1 - 0.15 11.8 1.7 1.9 8.2 0.1 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein IstB_IS21 PF01695.17 KKK24436.1 - 0.18 11.5 0.8 2.6 7.7 0.1 2.2 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF2075 PF09848.9 KKK24436.1 - 0.21 10.8 0.7 10 5.2 0.0 2.0 1 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) CbiA PF01656.23 KKK24436.1 - 0.22 11.6 0.6 0.93 9.6 0.6 2.0 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain WD40 PF00400.32 KKK24438.1 - 0.00013 22.7 12.7 4.8 8.2 0.0 6.7 7 1 0 7 7 7 2 WD domain, G-beta repeat Lactonase PF10282.9 KKK24438.1 - 0.014 14.7 0.0 0.026 13.8 0.0 1.4 1 0 0 1 1 1 0 Lactonase, 7-bladed beta-propeller ANAPC4_WD40 PF12894.7 KKK24438.1 - 0.026 14.8 0.0 27 5.1 0.0 3.7 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KKK24438.1 - 0.05 13.6 0.1 12 6.0 0.0 4.0 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Nucleoporin_FG PF13634.6 KKK24440.1 - 5.6e-06 27.1 81.8 0.0097 16.7 42.8 3.5 1 1 2 3 3 3 3 Nucleoporin FG repeat region DUF1664 PF07889.12 KKK24440.1 - 0.03 14.4 0.2 1.6 8.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Lectin_N PF03954.14 KKK24440.1 - 0.076 12.8 0.1 3.5 7.4 0.0 2.5 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain TrwC PF08751.11 KKK24440.1 - 0.087 12.3 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 TrwC relaxase DUF533 PF04391.12 KKK24440.1 - 3.5 7.2 5.5 8.7 5.9 5.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF533) PEP-utilisers_N PF05524.13 KKK24441.1 - 0.016 15.3 0.1 0.069 13.3 0.0 2.0 1 1 1 2 2 2 0 PEP-utilising enzyme, N-terminal PEMT PF04191.13 KKK24449.1 - 3.8e-58 194.4 8.0 8.5e-36 122.6 1.1 2.8 2 0 0 2 2 2 2 Phospholipid methyltransferase SKICH PF17751.1 KKK24449.1 - 0.0077 16.8 0.1 0.24 12.0 0.1 2.4 1 1 0 1 1 1 1 SKICH domain HECW_N PF16562.5 KKK24449.1 - 0.013 15.3 0.1 0.049 13.4 0.1 1.8 2 0 0 2 2 2 0 N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2 RNase_PH PF01138.21 KKK24450.1 - 3.3e-32 111.8 0.0 7.3e-32 110.6 0.0 1.6 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 HTH_AsnC-type PF13404.6 KKK24451.1 - 0.026 14.4 0.0 0.038 13.8 0.0 1.3 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain HAD_2 PF13419.6 KKK24452.1 - 2.4e-05 24.5 0.0 0.014 15.5 0.0 2.3 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KKK24452.1 - 0.0069 16.4 0.0 0.014 15.4 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 KKK24452.1 - 0.011 16.1 0.0 0.18 12.0 0.0 2.1 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase NAD_binding_4 PF07993.12 KKK24453.1 - 1.6e-33 115.9 0.0 2.3e-33 115.4 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.19 KKK24453.1 - 8.8e-05 21.6 0.0 0.001 18.2 0.0 2.1 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KKK24453.1 - 0.0013 18.2 0.0 0.0089 15.5 0.0 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KKK24453.1 - 0.0021 18.0 0.0 0.0037 17.2 0.0 1.4 1 0 0 1 1 1 1 KR domain SR-25 PF10500.9 KKK24454.1 - 6.6e-05 22.6 5.9 6.6e-05 22.6 5.9 2.1 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein CCDC106 PF15794.5 KKK24454.1 - 0.088 12.5 5.5 0.14 11.8 5.5 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 CDC45 PF02724.14 KKK24454.1 - 0.74 8.0 5.0 0.92 7.7 5.0 1.1 1 0 0 1 1 1 0 CDC45-like protein NAM-associated PF14303.6 KKK24454.1 - 4.7 7.9 13.3 0.28 11.9 7.5 1.8 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain GET2 PF08690.10 KKK24455.1 - 4.6e-18 65.9 0.0 3.3e-17 63.1 0.0 2.0 1 1 1 2 2 2 1 GET complex subunit GET2 SLAC1 PF03595.17 KKK24455.1 - 0.019 14.3 3.8 0.026 13.8 3.8 1.1 1 0 0 1 1 1 0 Voltage-dependent anion channel C2 PF00168.30 KKK24456.1 - 8.9e-29 99.8 0.0 6.4e-17 61.7 0.0 2.7 2 0 0 2 2 2 2 C2 domain Lin-8 PF03353.15 KKK24456.1 - 0.84 9.1 7.5 1.6 8.2 7.5 1.5 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist GREB1 PF15782.5 KKK24456.1 - 6.8 3.7 7.2 9.2 3.2 7.2 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer PIG-L PF02585.17 KKK24457.1 - 4.5e-17 62.9 0.0 8.6e-17 62.0 0.0 1.5 1 1 0 1 1 1 1 GlcNAc-PI de-N-acetylase PSI_PsaE PF02427.17 KKK24457.1 - 0.18 11.5 0.0 0.36 10.5 0.0 1.4 1 0 0 1 1 1 0 Photosystem I reaction centre subunit IV / PsaE APH PF01636.23 KKK24458.1 - 4.2e-11 43.2 0.0 8.9e-11 42.2 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Sugar_tr PF00083.24 KKK24459.1 - 7.3e-80 269.0 20.8 8.3e-80 268.8 20.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKK24459.1 - 4.4e-14 52.2 44.8 2.4e-10 39.9 31.2 3.0 1 1 2 3 3 3 3 Major Facilitator Superfamily zf-C2H2_4 PF13894.6 KKK24460.1 - 0.0014 19.3 3.5 0.031 15.1 0.1 2.9 2 0 0 2 2 2 1 C2H2-type zinc finger zf-Di19 PF05605.12 KKK24460.1 - 0.0058 16.9 1.7 0.62 10.4 0.1 2.3 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding Prok-RING_4 PF14447.6 KKK24460.1 - 0.006 16.4 0.7 1.6 8.6 0.1 2.4 2 0 0 2 2 2 2 Prokaryotic RING finger family 4 zf-C2H2_2 PF12756.7 KKK24460.1 - 0.0079 16.5 0.2 0.022 15.1 0.2 1.7 1 1 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-C2H2_9 PF16293.5 KKK24460.1 - 0.065 13.1 0.1 12 5.8 0.0 2.4 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) DZR PF12773.7 KKK24460.1 - 0.12 12.5 0.0 0.24 11.4 0.0 1.5 1 1 0 1 1 1 0 Double zinc ribbon zf-C2H2 PF00096.26 KKK24460.1 - 0.12 12.9 2.2 2.2 8.9 0.1 3.0 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-UDP PF14569.6 KKK24460.1 - 0.27 11.4 2.8 2.4 8.3 0.1 2.8 3 0 0 3 3 3 0 Zinc-binding RING-finger UPF0547 PF10571.9 KKK24460.1 - 0.36 11.0 2.5 0.8 9.8 0.2 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 DASH_Duo1 PF08651.10 KKK24470.1 - 2.6e-30 104.0 2.9 2.6e-30 104.0 2.9 1.8 2 0 0 2 2 2 1 DASH complex subunit Duo1 DUF745 PF05335.13 KKK24470.1 - 0.13 12.0 11.9 0.19 11.4 11.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF745) DASH_Dad2 PF08654.10 KKK24470.1 - 0.29 11.6 8.6 1.3 9.5 8.6 2.0 1 1 0 1 1 1 0 DASH complex subunit Dad2 BRF1 PF07741.13 KKK24470.1 - 8.8 6.7 13.6 8.1 6.9 6.4 2.3 2 0 0 2 2 2 0 Brf1-like TBP-binding domain RNase_H2-Ydr279 PF09468.10 KKK24471.1 - 7.6e-42 143.2 1.5 2e-41 141.8 1.5 1.7 1 1 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) wHTH domain Ydr279_N PF17745.1 KKK24471.1 - 4.6e-23 81.3 1.8 6.8e-23 80.7 0.1 2.1 2 0 0 2 2 2 1 Ydr279p protein triple barrel domain KdpA PF03814.15 KKK24471.1 - 3 5.9 4.0 5.6 5.0 0.0 2.0 2 0 0 2 2 2 0 Potassium-transporting ATPase A subunit CPSF100_C PF13299.6 KKK24471.1 - 8.8 6.5 9.7 15 5.7 3.5 2.2 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal zf-primase PF09329.11 KKK24472.1 - 7.6e-19 67.3 1.3 1.3e-18 66.5 1.3 1.4 1 0 0 1 1 1 1 Primase zinc finger Fungal_trans PF04082.18 KKK24473.1 - 1.5e-19 70.1 0.0 3.9e-19 68.7 0.0 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain GPI2 PF06432.11 KKK24474.1 - 1.5e-118 395.3 0.6 1.9e-118 395.0 0.6 1.1 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase DUF4716 PF15837.5 KKK24474.1 - 0.29 11.2 4.2 0.42 10.7 2.2 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4716) Glyco_hydro_18 PF00704.28 KKK24475.1 - 2.2e-81 274.0 0.1 2.6e-81 273.8 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 KKK24475.1 - 2.2e-07 31.2 19.9 4.2e-07 30.3 19.9 1.5 1 0 0 1 1 1 1 Chitin recognition protein Glyco_hydro_66 PF13199.6 KKK24475.1 - 0.069 11.8 0.0 0.13 10.9 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 66 Iso_dh PF00180.20 KKK24476.1 - 1.1e-87 294.5 0.0 1.2e-87 294.3 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Cofilin_ADF PF00241.20 KKK24478.1 - 3.8e-20 71.9 0.0 4.6e-20 71.6 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein TPP_enzyme_N PF02776.18 KKK24479.1 - 1.1e-31 109.8 0.0 2.1e-31 108.8 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 KKK24479.1 - 1.9e-15 56.8 0.0 4.7e-15 55.5 0.0 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 KKK24479.1 - 7.5e-15 55.0 0.0 3.5e-14 52.8 0.0 2.1 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Glycos_transf_1 PF00534.20 KKK24480.1 - 4.3e-14 52.4 0.0 6.7e-14 51.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KKK24480.1 - 2e-13 50.9 0.0 5.4e-13 49.5 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferases group 1 Methyltransf_11 PF08241.12 KKK24481.1 - 5.6e-22 78.2 0.0 1.6e-21 76.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKK24481.1 - 1.9e-19 70.2 0.0 5e-19 68.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KKK24481.1 - 5.7e-19 68.4 0.0 9e-19 67.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KKK24481.1 - 9.1e-14 51.6 0.0 1.4e-13 51.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KKK24481.1 - 9.5e-12 45.5 0.0 2.5e-11 44.2 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 KKK24481.1 - 6.2e-11 42.1 0.0 9.5e-11 41.5 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.20 KKK24481.1 - 3.2e-10 39.8 0.0 4.5e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MetW PF07021.12 KKK24481.1 - 0.00011 21.9 0.0 0.00018 21.2 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW MTS PF05175.14 KKK24481.1 - 0.00055 19.5 0.0 0.00098 18.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.6 KKK24481.1 - 0.0019 18.2 0.0 0.0039 17.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KKK24481.1 - 0.0092 15.7 0.0 0.014 15.1 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.13 KKK24481.1 - 0.014 14.8 0.0 0.024 14.0 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) TehB PF03848.14 KKK24481.1 - 0.019 14.4 0.0 0.033 13.6 0.0 1.4 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_8 PF05148.15 KKK24481.1 - 0.023 14.6 0.0 0.39 10.5 0.0 2.2 1 1 0 1 1 1 0 Hypothetical methyltransferase Methyltransf_2 PF00891.18 KKK24481.1 - 0.037 13.3 0.0 0.057 12.7 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain Cas_Csx8 PF09657.10 KKK24481.1 - 0.094 11.7 0.1 3.7 6.4 0.0 2.3 2 0 0 2 2 2 0 CRISPR-associated protein Csx8 (Cas_Csx8) RrnaAD PF00398.20 KKK24481.1 - 0.15 11.1 0.0 0.24 10.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Sugar_tr PF00083.24 KKK24483.1 - 4.9e-41 141.0 17.2 3.8e-28 98.5 2.9 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KKK24483.1 - 1.6e-25 89.8 22.1 1.6e-25 89.8 22.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4231 PF14015.6 KKK24483.1 - 0.24 11.9 0.8 37 4.8 0.1 3.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) Fe-ADH PF00465.19 KKK24490.1 - 8e-29 100.6 0.0 9e-29 100.4 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase LSM PF01423.22 KKK24491.1 - 6.5e-20 70.6 0.0 7.3e-20 70.4 0.0 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KKK24491.1 - 0.00036 20.6 0.1 0.00044 20.3 0.1 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.7 KKK24491.1 - 0.00048 20.2 0.2 0.00057 19.9 0.2 1.1 1 0 0 1 1 1 1 Scd6-like Sm domain Rad60-SLD PF11976.8 KKK24492.1 - 1e-19 70.1 0.0 1e-16 60.5 0.2 2.4 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 KKK24492.1 - 0.00039 20.1 0.0 0.12 12.2 0.0 2.5 2 0 0 2 2 2 2 Ubiquitin family His_Phos_2 PF00328.22 KKK24493.1 - 1.6e-110 370.1 0.2 2.3e-110 369.6 0.2 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PPIP5K2_N PF18086.1 KKK24493.1 - 5.4e-38 129.0 0.0 1.3e-37 127.8 0.0 1.6 1 0 0 1 1 1 1 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain RimK PF08443.11 KKK24493.1 - 4e-05 23.3 0.0 9.2e-05 22.1 0.0 1.5 1 0 0 1 1 1 1 RimK-like ATP-grasp domain Mito_fiss_reg PF05308.11 KKK24493.1 - 0.019 15.0 4.3 0.052 13.6 4.3 1.8 1 0 0 1 1 1 0 Mitochondrial fission regulator N-SET PF11764.8 KKK24494.1 - 4.5e-46 157.1 1.1 4.5e-46 157.1 1.1 3.0 3 0 0 3 3 3 1 COMPASS (Complex proteins associated with Set1p) component N SET_assoc PF11767.8 KKK24494.1 - 9.6e-28 95.6 0.5 2.8e-27 94.2 0.5 1.9 1 0 0 1 1 1 1 Histone lysine methyltransferase SET associated SET PF00856.28 KKK24494.1 - 2.2e-18 67.2 0.1 2.2e-18 67.2 0.1 3.2 3 1 0 3 3 3 1 SET domain RRM_1 PF00076.22 KKK24494.1 - 0.00016 21.5 0.0 0.0004 20.1 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MFS_1 PF07690.16 KKK24495.1 - 4.2e-06 25.9 49.9 0.00018 20.6 41.4 4.0 2 1 0 2 2 2 2 Major Facilitator Superfamily Thioredoxin PF00085.20 KKK24520.1 - 1e-59 198.9 0.3 5.4e-30 103.4 0.0 3.3 3 0 0 3 3 3 2 Thioredoxin MKT1_C PF12246.8 KKK24520.1 - 1.5e-56 191.3 0.0 2.5e-29 102.2 0.0 2.5 1 1 1 2 2 2 2 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.8 KKK24520.1 - 6.1e-30 103.4 0.0 1.6e-29 102.1 0.0 1.8 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication ERp29 PF07749.12 KKK24520.1 - 2.7e-21 76.3 2.1 3.9e-21 75.7 0.9 2.0 2 0 0 2 2 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_2 PF13098.6 KKK24520.1 - 1.3e-15 57.8 0.0 9.7e-07 29.2 0.0 3.3 2 0 0 2 2 2 2 Thioredoxin-like domain OST3_OST6 PF04756.13 KKK24520.1 - 6.8e-12 45.3 0.0 5.7e-07 29.2 0.0 2.3 1 1 1 2 2 2 2 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 KKK24520.1 - 1.7e-09 37.7 0.0 8.1e-05 22.7 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_8 PF13905.6 KKK24520.1 - 3.6e-08 33.6 0.0 0.0086 16.4 0.0 3.8 3 1 1 4 4 4 2 Thioredoxin-like XPG_I PF00867.18 KKK24520.1 - 2.7e-07 30.9 0.9 8.8e-07 29.2 0.0 2.4 3 0 0 3 3 2 1 XPG I-region AhpC-TSA PF00578.21 KKK24520.1 - 1.7e-06 28.0 0.0 0.057 13.3 0.0 2.6 2 0 0 2 2 2 2 AhpC/TSA family XPG_N PF00752.17 KKK24520.1 - 3.7e-05 24.1 0.0 0.00013 22.4 0.0 1.9 1 0 0 1 1 1 1 XPG N-terminal domain TraF PF13728.6 KKK24520.1 - 9.2e-05 22.4 0.0 0.11 12.3 0.0 2.6 2 0 0 2 2 2 2 F plasmid transfer operon protein Redoxin PF08534.10 KKK24520.1 - 0.00016 21.4 0.1 0.31 10.8 0.0 2.7 2 0 0 2 2 2 2 Redoxin HyaE PF07449.11 KKK24520.1 - 0.00094 19.1 0.0 0.17 11.8 0.0 2.7 2 0 0 2 2 2 1 Hydrogenase-1 expression protein HyaE Thioredoxin_9 PF14595.6 KKK24520.1 - 0.022 14.5 0.0 6.5 6.5 0.0 2.5 2 0 0 2 2 2 0 Thioredoxin Laps PF10169.9 KKK24520.1 - 0.65 10.6 3.5 1.3 9.6 3.5 1.5 1 0 0 1 1 1 0 Learning-associated protein zf-MYND PF01753.18 KKK24521.1 - 6.5e-08 32.5 20.3 1.5e-07 31.3 20.3 1.7 1 0 0 1 1 1 1 MYND finger DIOX_N PF14226.6 KKK24522.1 - 2.8e-20 73.2 0.1 4.4e-20 72.6 0.1 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KKK24522.1 - 8.7e-07 29.4 0.0 2.3e-06 28.0 0.0 1.8 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily HSBP1 PF06825.12 KKK24523.1 - 5.9e-17 61.3 0.2 8.5e-17 60.7 0.2 1.2 1 0 0 1 1 1 1 Heat shock factor binding protein 1 Matrilin_ccoil PF10393.9 KKK24523.1 - 0.00049 19.9 0.9 0.0045 16.8 0.9 2.0 1 1 0 1 1 1 1 Trimeric coiled-coil oligomerisation domain of matrilin Apolipoprotein PF01442.18 KKK24523.1 - 0.0029 17.5 0.1 0.0036 17.2 0.1 1.1 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF2937 PF11157.8 KKK24523.1 - 0.009 15.7 0.1 0.0096 15.6 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2937) Baculo_PEP_C PF04513.12 KKK24523.1 - 0.016 15.3 0.1 0.021 14.9 0.1 1.1 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.12 KKK24523.1 - 0.018 15.5 0.1 0.023 15.2 0.1 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein CLZ PF16526.5 KKK24523.1 - 0.022 15.1 0.1 0.029 14.7 0.1 1.2 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels SPX PF03105.19 KKK24523.1 - 0.077 12.9 0.0 0.085 12.8 0.0 1.0 1 0 0 1 1 1 0 SPX domain BMFP PF04380.13 KKK24523.1 - 0.085 13.3 0.6 0.75 10.3 0.6 2.0 1 1 0 1 1 1 0 Membrane fusogenic activity Pex19 PF04614.12 KKK24523.1 - 0.096 12.4 0.3 0.11 12.3 0.3 1.0 1 0 0 1 1 1 0 Pex19 protein family CCDC154 PF15450.6 KKK24523.1 - 0.11 11.1 0.1 0.13 10.8 0.1 1.0 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 154 FdhE PF04216.12 KKK24523.1 - 0.13 12.1 0.1 0.13 12.1 0.1 1.0 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation Fzo_mitofusin PF04799.13 KKK24523.1 - 0.13 11.8 0.0 0.15 11.6 0.0 1.1 1 0 0 1 1 1 0 fzo-like conserved region Tup_N PF08581.10 KKK24523.1 - 0.15 12.4 0.2 0.26 11.6 0.2 1.5 1 1 0 1 1 1 0 Tup N-terminal DUF4878 PF12870.7 KKK24523.1 - 0.17 12.2 0.0 0.22 11.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4878) DUF1771 PF08590.10 KKK24524.1 - 7.7e-26 90.3 8.2 7.7e-26 90.3 8.2 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) Smr PF01713.21 KKK24524.1 - 4.2e-11 43.0 1.4 1.2e-10 41.6 0.2 2.3 2 0 0 2 2 2 1 Smr domain BET PF17035.5 KKK24524.1 - 0.041 14.1 0.1 0.086 13.0 0.1 1.6 1 0 0 1 1 1 0 Bromodomain extra-terminal - transcription regulation DUF3461 PF11944.8 KKK24524.1 - 0.12 12.5 1.8 6.5 6.9 0.5 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3461) SurA_N_2 PF13623.6 KKK24524.1 - 0.18 11.7 10.0 0.49 10.3 10.0 1.7 1 0 0 1 1 1 0 SurA N-terminal domain DUF4407 PF14362.6 KKK24524.1 - 0.34 10.2 15.6 0.2 11.0 4.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) OmpH PF03938.14 KKK24524.1 - 1.8 8.9 24.3 0.95 9.8 11.0 2.5 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) Spt20 PF12090.8 KKK24524.1 - 2.1 7.9 24.0 0.041 13.5 17.0 1.7 2 0 0 2 2 2 0 Spt20 family FAM60A PF15396.6 KKK24524.1 - 4.5 7.2 10.4 0.22 11.5 2.3 2.0 1 1 0 2 2 2 0 Protein Family FAM60A CDC14 PF08045.11 KKK24525.1 - 7.1e-129 428.9 0.0 8e-129 428.8 0.0 1.0 1 0 0 1 1 1 1 Cell division control protein 14, SIN component polyprenyl_synt PF00348.17 KKK24526.1 - 6.7e-64 215.4 0.0 8.5e-64 215.1 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase GST_N_4 PF17172.4 KKK24527.1 - 6.9e-19 68.4 0.1 2.7e-18 66.5 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 KKK24527.1 - 4e-17 61.8 0.1 9.6e-17 60.5 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 KKK24527.1 - 1.1e-11 45.1 1.6 1.2e-10 41.8 0.6 2.6 1 1 1 2 2 2 1 Outer mitochondrial membrane transport complex protein GST_C_2 PF13410.6 KKK24527.1 - 0.00051 20.0 0.1 0.00099 19.1 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain FA_hydroxylase PF04116.13 KKK24529.1 - 3.8e-22 79.0 9.2 3.8e-22 79.0 9.2 2.1 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily MscL PF01741.18 KKK24530.1 - 5.6e-18 65.4 0.2 7.7e-18 65.0 0.2 1.2 1 0 0 1 1 1 1 Large-conductance mechanosensitive channel, MscL Ig_GlcNase PF18368.1 KKK24531.1 - 6.1e-30 103.5 1.1 1.7e-29 102.1 0.2 2.2 2 0 0 2 2 2 1 Exo-beta-D-glucosaminidase Ig-fold domain Glyco_hydro_2 PF00703.21 KKK24531.1 - 4.8e-12 46.5 0.6 1.1e-11 45.4 0.0 1.9 3 0 0 3 3 3 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.18 KKK24531.1 - 0.0037 17.2 0.0 0.0073 16.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.17 KKK24531.1 - 0.0057 15.8 0.0 0.009 15.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Ig_mannosidase PF17753.1 KKK24531.1 - 0.05 13.4 0.0 0.14 11.9 0.0 1.7 1 0 0 1 1 1 0 Ig-fold domain Mannosidase_ig PF17786.1 KKK24531.1 - 0.15 12.7 0.7 1.7 9.3 0.0 2.6 1 1 1 2 2 2 0 Mannosidase Ig/CBM-like domain Glyco_hydro_76 PF03663.14 KKK24532.1 - 6.1e-158 526.1 22.5 9e-158 525.6 22.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 ADH_N PF08240.12 KKK24532.1 - 2.3e-25 88.6 0.3 1.8e-24 85.7 0.1 2.4 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KKK24532.1 - 3.1e-21 75.7 1.5 6.5e-21 74.7 1.5 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KKK24532.1 - 4.8e-06 27.7 0.1 1e-05 26.6 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase F-box-like PF12937.7 KKK24533.1 - 0.00087 19.1 1.3 0.013 15.4 0.2 2.6 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KKK24533.1 - 0.0016 18.3 0.2 0.0052 16.6 0.2 1.9 1 0 0 1 1 1 1 F-box domain Sugar_tr PF00083.24 KKK24534.1 - 6.1e-133 444.0 20.8 7e-133 443.8 20.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKK24534.1 - 7.3e-22 77.8 36.2 1.1e-11 44.3 11.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF962 PF06127.11 KKK24534.1 - 0.22 11.6 0.0 0.22 11.6 0.0 2.3 3 1 0 3 3 3 0 Protein of unknown function (DUF962) DUF3430 PF11912.8 KKK24535.1 - 0.04 13.9 0.0 0.048 13.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3430) Cutinase PF01083.22 KKK24536.1 - 7.9e-40 136.7 0.1 1.2e-39 136.1 0.1 1.2 1 0 0 1 1 1 1 Cutinase Abhydrolase_2 PF02230.16 KKK24536.1 - 0.0022 17.9 0.0 0.0038 17.0 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 KKK24536.1 - 0.0045 16.3 0.0 0.0074 15.6 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PE-PPE PF08237.11 KKK24536.1 - 0.0047 16.5 0.0 0.0075 15.8 0.0 1.3 1 0 0 1 1 1 1 PE-PPE domain Amidase PF01425.21 KKK24537.1 - 7.3e-89 298.8 0.0 2.8e-88 296.9 0.0 1.7 1 1 0 1 1 1 1 Amidase Glyco_hydro_3_C PF01915.22 KKK24538.1 - 1.1e-51 175.7 0.0 1.7e-51 175.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KKK24538.1 - 1.6e-45 155.9 0.0 2.6e-45 155.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KKK24538.1 - 6e-26 90.3 0.0 1.5e-25 89.1 0.0 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain p450 PF00067.22 KKK24539.1 - 6e-76 256.1 0.0 8.9e-76 255.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.18 KKK24539.1 - 3.7e-10 39.3 0.1 6.7e-10 38.4 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Aldedh PF00171.22 KKK24541.1 - 3.4e-07 29.1 0.0 4e-07 28.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Na_Ca_ex PF01699.24 KKK24543.1 - 9.8e-32 110.0 30.9 5e-17 62.3 8.5 2.4 3 0 0 3 3 3 2 Sodium/calcium exchanger protein Neurokinin_B PF03823.14 KKK24543.1 - 0.11 12.5 0.1 0.6 10.2 0.1 2.3 1 0 0 1 1 1 0 Neurokinin B Trypan_PARP PF05887.11 KKK24543.1 - 0.27 11.2 4.0 2.5 8.1 1.9 2.5 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) DUF3995 PF13160.6 KKK24543.1 - 2.6 8.4 7.4 0.65 10.4 0.5 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3995) Fungal_trans PF04082.18 KKK24544.1 - 8.7e-18 64.3 0.0 2.2e-17 62.9 0.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK24544.1 - 5.4e-05 23.2 7.6 0.00011 22.3 7.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short_C2 PF13561.6 KKK24545.1 - 5.1e-32 111.3 0.0 5.8e-32 111.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KKK24545.1 - 8.5e-16 58.0 0.0 1.6e-15 57.1 0.0 1.4 2 0 0 2 2 2 1 short chain dehydrogenase Usp PF00582.26 KKK24550.1 - 2.2e-18 67.1 4.0 2.8e-17 63.6 0.8 3.1 2 1 0 2 2 2 1 Universal stress protein family ATP-synt_ab PF00006.25 KKK24551.1 - 2.9e-68 229.7 0.0 4.8e-68 229.0 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 KKK24551.1 - 2.3e-12 47.2 0.3 4.6e-12 46.3 0.3 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain Spt5_N PF11942.8 KKK24553.1 - 0.0067 17.4 7.5 0.019 15.9 4.6 2.3 2 0 0 2 2 2 1 Spt5 transcription elongation factor, acidic N-terminal Myc_N PF01056.18 KKK24553.1 - 0.035 14.0 2.4 0.062 13.2 2.4 1.5 1 0 0 1 1 1 0 Myc amino-terminal region D123 PF07065.14 KKK24553.1 - 0.036 13.2 0.4 0.054 12.6 0.4 1.2 1 0 0 1 1 1 0 D123 FAM176 PF14851.6 KKK24553.1 - 0.037 13.7 2.9 0.079 12.6 2.9 1.5 1 0 0 1 1 1 0 FAM176 family E7 PF00527.18 KKK24553.1 - 0.42 10.8 3.4 0.99 9.6 3.4 1.5 1 0 0 1 1 1 0 E7 protein, Early protein CENP-B_dimeris PF09026.10 KKK24553.1 - 1.1 9.6 10.1 2.3 8.7 10.1 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain CDC45 PF02724.14 KKK24553.1 - 6.6 4.9 6.7 0.18 10.0 0.9 1.4 2 0 0 2 2 2 0 CDC45-like protein DNA_pol_phi PF04931.13 KKK24553.1 - 6.9 4.6 7.7 9.3 4.2 7.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi BCDHK_Adom3 PF10436.9 KKK24555.1 - 1.4e-74 249.4 0.0 1.8e-74 249.0 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 KKK24555.1 - 1.6e-09 38.3 0.0 3.1e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KKK24555.1 - 0.2 11.5 0.0 0.36 10.6 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase NUFIP1 PF10453.9 KKK24556.1 - 8.5e-16 57.5 2.9 8.5e-16 57.5 2.9 3.0 2 0 0 2 2 2 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) zf-CCCH PF00642.24 KKK24556.1 - 1.8e-07 30.9 2.6 3.3e-07 30.1 2.6 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 KKK24556.1 - 6e-06 25.9 3.6 1e-05 25.2 3.6 1.4 1 0 0 1 1 1 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 KKK24556.1 - 1.8e-05 24.6 6.4 3e-05 23.9 6.4 1.3 1 0 0 1 1 1 1 Zinc finger domain Torus PF16131.5 KKK24556.1 - 0.00071 20.2 0.0 0.00071 20.2 0.0 3.4 3 0 0 3 3 3 1 Torus domain DUF3584 PF12128.8 KKK24556.1 - 2.5 5.5 21.1 3.3 5.1 21.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) RNA_pol_Rbc25 PF08292.12 KKK24557.1 - 3.1e-35 121.2 1.1 2.3e-34 118.4 1.1 2.0 1 1 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.17 KKK24557.1 - 1.1e-14 54.6 0.0 1.8e-14 53.8 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 Cys_Met_Meta_PP PF01053.20 KKK24558.1 - 1.1e-142 475.1 0.1 1.3e-142 474.9 0.1 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 KKK24558.1 - 3.1e-08 33.2 0.2 5.7e-08 32.3 0.2 1.4 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KKK24558.1 - 2.4e-07 30.1 0.5 4.3e-07 29.2 0.5 1.4 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 KKK24558.1 - 1.7e-06 27.6 0.4 2.9e-06 26.8 0.4 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 KKK24558.1 - 0.0017 17.7 0.1 0.0041 16.5 0.1 1.7 1 1 0 1 1 1 1 Beta-eliminating lyase Asp_Arg_Hydrox PF05118.15 KKK24558.1 - 0.075 12.8 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 Aspartyl/Asparaginyl beta-hydroxylase Methyltransf_16 PF10294.9 KKK24559.1 - 5.5e-06 26.2 0.0 0.00048 19.9 0.0 2.2 2 0 0 2 2 2 2 Lysine methyltransferase TRAP_alpha PF03896.16 KKK24559.1 - 0.003 16.8 0.4 0.0046 16.2 0.4 1.2 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit Ribosomal_60s PF00428.19 KKK24559.1 - 0.0047 17.5 0.7 0.0047 17.5 0.7 2.2 2 0 0 2 2 2 1 60s Acidic ribosomal protein Myc_N PF01056.18 KKK24559.1 - 0.062 13.2 0.3 0.091 12.6 0.3 1.2 1 0 0 1 1 1 0 Myc amino-terminal region Pyr_redox_2 PF07992.14 KKK24561.1 - 9.8e-07 28.3 0.1 3.5e-06 26.5 0.1 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KKK24561.1 - 1.3e-05 25.2 0.3 0.0021 18.1 0.5 3.0 2 1 0 2 2 2 1 FAD-NAD(P)-binding K_oxygenase PF13434.6 KKK24561.1 - 0.00087 18.5 0.0 0.012 14.7 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 KKK24561.1 - 0.07 12.4 0.2 8.1 5.6 0.8 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GPI-anchored PF10342.9 KKK24562.1 - 3.7e-21 75.7 2.8 3.7e-21 75.7 2.8 2.7 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family SOG2 PF10428.9 KKK24562.1 - 0.53 9.4 18.9 0.62 9.2 18.9 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Tmemb_cc2 PF10267.9 KKK24562.1 - 1.3 8.1 3.6 1.4 8.0 3.6 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Plasmodium_Vir PF05795.11 KKK24562.1 - 2.4 7.5 3.9 2.7 7.3 3.9 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Macoilin PF09726.9 KKK24562.1 - 6 5.3 8.4 6.5 5.2 8.4 1.0 1 0 0 1 1 1 0 Macoilin family SR-25 PF10500.9 KKK24562.1 - 9.1 5.8 15.2 28 4.2 15.8 1.5 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Apt1 PF10351.9 KKK24562.1 - 9.4 5.0 8.7 11 4.7 8.7 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Hamartin PF04388.12 KKK24562.1 - 9.6 4.7 11.4 9.6 4.7 11.4 1.1 1 0 0 1 1 1 0 Hamartin protein SF-assemblin PF06705.11 KKK24564.1 - 2.1 7.6 46.6 4.6 6.5 18.1 2.6 1 1 1 2 2 2 0 SF-assemblin/beta giardin DUF4407 PF14362.6 KKK24564.1 - 2.2 7.5 52.6 0.37 10.1 20.7 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF4407) STT3 PF02516.14 KKK24565.1 - 1.1e-145 486.3 34.4 1.6e-140 469.3 32.4 2.2 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit Dpy19 PF10034.9 KKK24565.1 - 0.024 12.9 1.1 0.032 12.4 0.0 1.8 2 1 0 2 2 2 0 Q-cell neuroblast polarisation ATP-synt_E PF05680.12 KKK24566.1 - 1.1e-20 73.7 0.3 1.3e-20 73.6 0.3 1.0 1 0 0 1 1 1 1 ATP synthase E chain YqjK PF13997.6 KKK24566.1 - 0.013 15.7 0.6 0.76 10.1 0.2 2.1 2 0 0 2 2 2 0 YqjK-like protein UCR_14kD PF02271.16 KKK24566.1 - 0.056 13.4 0.0 0.062 13.3 0.0 1.1 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase complex 14kD subunit Adhesin_P1_N PF18652.1 KKK24566.1 - 2.2 8.4 7.0 2.8 8.0 2.9 2.5 1 1 1 2 2 2 0 Adhesin P1 N-terminal domain CSN8_PSD8_EIF3K PF10075.9 KKK24567.1 - 2.7e-35 121.4 0.0 3.3e-35 121.2 0.0 1.1 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family SAC3_GANP PF03399.16 KKK24567.1 - 0.036 13.4 0.1 0.043 13.2 0.1 1.1 1 0 0 1 1 1 0 SAC3/GANP family Coiled-coil_56 PF09813.9 KKK24568.1 - 5.7e-05 23.1 0.0 6.3e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 56 APH PF01636.23 KKK24569.1 - 2.2e-15 57.3 0.0 8.5e-15 55.3 0.0 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 KKK24569.1 - 0.00039 19.4 0.1 0.16 10.8 0.1 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1679) DUF3453 PF11935.8 KKK24570.1 - 1.8e-74 250.2 1.0 3.7e-74 249.2 0.6 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3453) MFS_1 PF07690.16 KKK24571.1 - 1.4e-30 106.4 30.4 1.7e-30 106.2 30.4 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KKK24571.1 - 8e-08 31.6 17.1 6.1e-07 28.6 11.6 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter DUF2157 PF09925.9 KKK24571.1 - 4.8 7.0 12.1 12 5.7 0.5 2.8 2 1 0 2 2 2 0 Predicted membrane protein (DUF2157) Lin-8 PF03353.15 KKK24572.1 - 1.6 8.2 3.4 2.5 7.6 3.4 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist RRM_1 PF00076.22 KKK24573.1 - 3.4e-09 36.4 0.1 1.5e-05 24.8 0.0 3.0 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.32 KKK24574.1 - 2.6e-05 24.9 7.3 3.7 8.6 0.1 5.8 5 1 0 5 5 5 3 WD domain, G-beta repeat DNA_pol_phi PF04931.13 KKK24574.1 - 0.19 9.8 5.4 0.27 9.3 5.4 1.1 1 0 0 1 1 1 0 DNA polymerase phi Sds3 PF08598.11 KKK24575.1 - 6.5e-19 68.8 0.0 1.2e-18 67.9 0.0 1.6 1 0 0 1 1 1 1 Sds3-like DUF1487 PF07368.11 KKK24575.1 - 0.092 12.2 0.4 1.8 7.9 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1487) zf-C2H2 PF00096.26 KKK24576.1 - 1.3e-05 25.4 23.0 0.097 13.2 0.3 4.6 4 0 0 4 4 4 4 Zinc finger, C2H2 type FOXP-CC PF16159.5 KKK24576.1 - 0.0048 17.5 0.9 0.0048 17.5 0.9 3.1 2 1 1 3 3 3 1 FOXP coiled-coil domain DUF629 PF04780.12 KKK24576.1 - 0.47 8.9 5.1 1 7.8 5.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF629) PRKCSH PF07915.13 KKK24577.1 - 1.9e-20 73.6 0.2 4.7e-20 72.4 0.2 1.7 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.6 KKK24577.1 - 0.011 15.4 0.2 0.16 11.7 0.2 2.2 1 1 0 1 1 1 0 Glucosidase II beta subunit-like protein Rota_NSP3 PF01665.16 KKK24577.1 - 0.087 11.9 0.6 0.14 11.3 0.6 1.2 1 0 0 1 1 1 0 Rotavirus non-structural protein NSP3 RasGAP PF00616.19 KKK24577.1 - 0.3 10.7 0.6 0.63 9.7 0.6 1.5 1 0 0 1 1 1 0 GTPase-activator protein for Ras-like GTPase SHD1 PF03983.12 KKK24578.1 - 5.1e-34 115.9 0.0 9.2e-34 115.1 0.0 1.4 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_1 PF00018.28 KKK24578.1 - 2.2e-33 113.6 5.7 1.4e-11 43.8 0.1 4.2 4 0 0 4 4 4 3 SH3 domain SH3_9 PF14604.6 KKK24578.1 - 3.7e-30 103.5 8.1 6.7e-13 48.3 0.2 3.8 4 0 0 4 4 4 3 Variant SH3 domain SH3_2 PF07653.17 KKK24578.1 - 1.7e-20 72.4 0.3 1.4e-08 34.3 0.0 4.4 4 0 0 4 4 4 4 Variant SH3 domain DUF1720 PF08226.11 KKK24578.1 - 2.5e-09 37.4 30.5 2.5e-09 37.4 30.5 6.2 1 1 2 4 4 4 2 Domain of unknown function (DUF1720) SAM_4 PF18017.1 KKK24578.1 - 0.00047 20.1 0.0 0.001 19.0 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_10 PF17902.1 KKK24578.1 - 0.0025 17.8 0.1 1.3 9.2 0.0 3.4 3 0 0 3 3 3 1 SH3 domain SH3_3 PF08239.11 KKK24578.1 - 0.017 15.4 4.5 0.48 10.8 0.8 2.7 2 0 0 2 2 2 0 Bacterial SH3 domain SIN1_PH PF16979.5 KKK24578.1 - 0.12 12.6 0.1 22 5.4 0.1 3.2 2 1 0 2 2 2 0 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology PMT PF02366.18 KKK24579.1 - 6.2e-86 288.0 18.3 9.9e-86 287.3 18.3 1.3 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 KKK24579.1 - 2.5e-70 236.1 3.2 2.5e-70 236.1 3.2 2.9 2 1 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 KKK24579.1 - 5.9e-20 71.9 0.3 9e-20 71.3 0.3 1.2 1 0 0 1 1 1 1 MIR domain Pirin PF02678.16 KKK24580.1 - 1.6e-28 98.8 0.2 3.3e-28 97.8 0.2 1.5 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.13 KKK24580.1 - 7.9e-24 84.0 0.0 3.2e-23 82.1 0.0 1.9 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.11 KKK24580.1 - 5.3e-05 22.9 2.1 0.00012 21.7 1.2 2.1 2 0 0 2 2 2 1 Cupin domain Cupin_3 PF05899.12 KKK24580.1 - 0.14 11.9 0.2 0.41 10.4 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF861) CDC50 PF03381.15 KKK24587.1 - 5.8e-98 327.8 0.0 7.1e-98 327.6 0.0 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family DUF3185 PF11381.8 KKK24587.1 - 2.3 8.3 7.0 3.3 7.8 0.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3185) SWIRM PF04433.17 KKK24588.1 - 1.5e-11 44.5 0.0 2.9e-11 43.6 0.0 1.5 1 0 0 1 1 1 1 SWIRM domain SPT16 PF08644.11 KKK24589.1 - 4.7e-57 192.4 0.1 1.2e-56 191.0 0.1 1.8 1 0 0 1 1 1 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.6 KKK24589.1 - 1.6e-53 180.8 0.0 1.1e-52 178.1 0.0 2.6 3 0 0 3 3 3 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.24 KKK24589.1 - 8.9e-26 90.9 0.0 1.5e-25 90.1 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.12 KKK24589.1 - 8e-14 51.8 0.2 3e-13 50.0 0.0 2.0 2 0 0 2 2 2 1 Histone chaperone Rttp106-like DUF3956 PF13104.6 KKK24589.1 - 0.19 12.0 0.1 0.37 11.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3956) Peptidase_M43 PF05572.13 KKK24590.1 - 6.9e-13 48.8 0.0 2e-12 47.2 0.0 1.8 2 0 0 2 2 2 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 KKK24590.1 - 0.0017 18.5 3.9 0.0061 16.7 3.9 2.0 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 KKK24590.1 - 0.0028 17.3 0.0 0.0057 16.3 0.0 1.6 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 KKK24590.1 - 0.006 17.1 0.2 0.012 16.1 0.2 1.6 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 KKK24590.1 - 0.092 12.6 2.7 0.26 11.1 2.7 2.0 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like DUF382 PF04037.13 KKK24591.1 - 5.5e-58 194.6 0.7 1.1e-57 193.6 0.7 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF382) PSP PF04046.16 KKK24591.1 - 1.2e-19 69.9 7.3 2.8e-19 68.7 7.3 1.7 1 0 0 1 1 1 1 PSP Sugar_tr PF00083.24 KKK24592.1 - 9.7e-102 341.1 11.3 1.3e-101 340.8 11.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKK24592.1 - 1.4e-31 109.7 25.1 1.9e-31 109.3 17.6 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Mito_carr PF00153.27 KKK24592.1 - 9.3e-17 60.8 0.0 9.8e-11 41.4 0.0 2.8 2 0 0 2 2 2 2 Mitochondrial carrier protein MFS_2 PF13347.6 KKK24592.1 - 1.8e-06 26.8 18.4 3.7e-05 22.5 5.6 2.6 3 0 0 3 3 3 2 MFS/sugar transport protein MFS_1_like PF12832.7 KKK24592.1 - 0.003 16.5 4.3 0.52 9.1 1.3 2.3 1 1 0 2 2 2 2 MFS_1 like family PMT PF02366.18 KKK24593.1 - 2.8e-87 292.4 16.4 2.8e-87 292.4 16.4 2.0 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 KKK24593.1 - 1.6e-62 210.6 18.2 1.6e-62 210.6 18.2 2.4 2 1 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 KKK24593.1 - 1.6e-37 129.2 0.4 2.5e-37 128.5 0.4 1.2 1 0 0 1 1 1 1 MIR domain Ras PF00071.22 KKK24594.1 - 8.6e-48 162.0 0.0 7.9e-37 126.3 0.0 2.1 2 0 0 2 2 2 2 Ras family Roc PF08477.13 KKK24594.1 - 4.2e-28 98.0 0.0 1.1e-17 64.3 0.0 2.2 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKK24594.1 - 3.4e-11 42.9 0.0 2e-10 40.4 0.0 1.9 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KKK24594.1 - 1.2e-08 34.7 0.0 2.2e-07 30.6 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KKK24594.1 - 1.1e-05 24.9 0.0 2.8e-05 23.6 0.0 1.7 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KKK24594.1 - 0.00022 21.3 0.0 0.0025 17.9 0.0 2.4 2 1 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KKK24594.1 - 0.00099 19.1 0.0 0.35 10.8 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 KKK24594.1 - 0.084 13.1 0.3 0.52 10.6 0.3 2.2 1 1 0 1 1 1 0 AAA domain Flu_M1_C PF08289.11 KKK24594.1 - 0.14 12.4 0.0 0.22 11.7 0.0 1.3 1 0 0 1 1 1 0 Influenza Matrix protein (M1) C-terminal domain AAA_25 PF13481.6 KKK24594.1 - 0.14 11.7 0.0 18 4.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 KKK24594.1 - 0.17 12.3 0.2 1.6 9.1 0.1 2.0 2 0 0 2 2 2 0 AAA ATPase domain Choline_transpo PF04515.12 KKK24595.1 - 1.3e-23 83.7 23.5 1.3e-23 83.7 23.5 2.4 2 0 0 2 2 2 1 Plasma-membrane choline transporter LSM PF01423.22 KKK24599.1 - 2.9e-16 58.9 0.1 4.3e-16 58.3 0.1 1.3 1 0 0 1 1 1 1 LSM domain WH2 PF02205.20 KKK24600.1 - 9.4e-09 34.8 0.4 2.6e-08 33.4 0.4 1.8 1 0 0 1 1 1 1 WH2 motif DUF5529 PF17669.1 KKK24601.1 - 0.024 14.7 0.9 0.054 13.5 0.3 1.8 1 1 1 2 2 2 0 Family of unknown function (DUF5529) Use1 PF09753.9 KKK24601.1 - 0.12 12.1 0.5 0.17 11.6 0.5 1.2 1 0 0 1 1 1 0 Membrane fusion protein Use1 DUF4336 PF14234.6 KKK24601.1 - 0.13 11.4 0.0 0.19 10.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4336) Ribosomal_L1 PF00687.21 KKK24602.1 - 1.3e-47 162.2 0.3 1.5e-47 162.0 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family SNF PF00209.18 KKK24602.1 - 0.026 13.2 0.1 0.036 12.8 0.1 1.1 1 0 0 1 1 1 0 Sodium:neurotransmitter symporter family Fungal_trans PF04082.18 KKK24603.1 - 1.8e-18 66.6 1.4 2.8e-18 65.9 1.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain CorA PF01544.18 KKK24604.1 - 0.0002 20.8 2.6 0.012 15.0 0.7 2.4 2 1 0 2 2 2 2 CorA-like Mg2+ transporter protein SieB PF14163.6 KKK24604.1 - 0.29 10.6 2.2 0.8 9.2 2.2 1.7 1 0 0 1 1 1 0 Super-infection exclusion protein B Arf PF00025.21 KKK24605.1 - 9.4e-80 266.2 0.1 1.1e-79 265.9 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KKK24605.1 - 5.5e-15 55.3 0.0 6.8e-15 55.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 KKK24605.1 - 3.2e-14 53.2 0.0 4.3e-14 52.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 KKK24605.1 - 2.3e-13 50.0 1.3 2e-09 37.1 0.3 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 KKK24605.1 - 5.2e-13 48.9 0.0 5.8e-13 48.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 KKK24605.1 - 2.5e-10 40.1 0.0 3.2e-10 39.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KKK24605.1 - 4.3e-06 26.8 0.0 6.4e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 KKK24605.1 - 0.011 15.1 0.4 0.022 14.1 0.4 1.7 1 1 0 1 1 1 0 6-phosphofructo-2-kinase HofP PF10748.9 KKK24606.1 - 0.1 12.2 0.5 0.16 11.6 0.0 1.5 2 0 0 2 2 2 0 DNA utilization proteins HofP DUF3405 PF11885.8 KKK24607.1 - 8.3e-233 773.7 0.4 9.8e-233 773.4 0.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) DUF4692 PF15763.5 KKK24607.1 - 0.25 11.8 2.2 0.42 11.1 2.2 1.3 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) Sod_Cu PF00080.20 KKK24608.1 - 4.1e-10 40.0 0.0 6.2e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) bZIP_1 PF00170.21 KKK24610.1 - 3.6e-08 33.4 12.9 7.4e-08 32.4 12.9 1.5 1 0 0 1 1 1 1 bZIP transcription factor PAP1 PF08601.10 KKK24610.1 - 0.0012 18.7 0.2 0.0012 18.7 0.2 2.6 2 1 1 3 3 2 1 Transcription factor PAP1 bZIP_2 PF07716.15 KKK24610.1 - 0.0016 18.4 16.6 0.0023 18.0 14.9 1.9 1 1 1 2 2 2 1 Basic region leucine zipper NRBF2 PF08961.10 KKK24610.1 - 0.014 15.0 0.5 0.023 14.3 0.5 1.4 1 0 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator PSI_PsaF PF02507.15 KKK24610.1 - 0.018 14.9 1.1 0.029 14.2 1.1 1.2 1 0 0 1 1 1 0 Photosystem I reaction centre subunit III V_ATPase_I PF01496.19 KKK24610.1 - 0.02 12.9 0.2 0.022 12.7 0.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family UPF0242 PF06785.11 KKK24610.1 - 0.021 15.0 3.6 0.032 14.3 3.6 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus TMF_TATA_bd PF12325.8 KKK24610.1 - 0.052 13.8 5.0 0.1 12.8 5.0 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding bZIP_Maf PF03131.17 KKK24610.1 - 0.081 13.5 9.8 0.14 12.7 9.8 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor SHE3 PF17078.5 KKK24610.1 - 0.15 11.8 4.9 0.24 11.1 4.9 1.3 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 DUF5094 PF17015.5 KKK24610.1 - 0.27 11.3 3.7 0.51 10.4 3.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5094) Pkinase PF00069.25 KKK24611.1 - 3.7e-26 92.1 0.0 5e-26 91.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK24611.1 - 8.1e-14 51.5 0.0 1.2e-13 51.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KKK24611.1 - 4.7e-09 35.5 0.0 7.3e-09 34.9 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KKK24611.1 - 0.00022 21.2 0.0 0.0016 18.4 0.0 2.1 1 1 0 2 2 2 1 Phosphotransferase enzyme family ACT_7 PF13840.6 KKK24612.1 - 6.2e-24 83.6 0.3 5.6e-16 58.1 0.0 3.5 3 0 0 3 3 3 3 ACT domain LisH_TPL PF17814.1 KKK24612.1 - 0.0038 16.8 0.3 0.012 15.3 0.3 1.8 1 0 0 1 1 1 1 LisH-like dimerisation domain MDD_C PF18376.1 KKK24614.1 - 1.3e-64 217.4 0.0 1.7e-64 217.0 0.0 1.2 1 0 0 1 1 1 1 Mevalonate 5-diphosphate decarboxylase C-terminal domain GHMP_kinases_N PF00288.26 KKK24614.1 - 2.4e-09 37.3 0.6 8.5e-09 35.5 0.6 2.0 1 0 0 1 1 1 1 GHMP kinases N terminal domain Dicer_dimer PF03368.14 KKK24614.1 - 0.0037 17.4 0.1 0.013 15.7 0.0 1.9 1 1 0 2 2 2 1 Dicer dimerisation domain zf-C2H2 PF00096.26 KKK24615.1 - 0.031 14.7 24.3 0.068 13.7 1.4 4.9 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-CHCC PF10276.9 KKK24615.1 - 0.82 9.8 4.0 9.6 6.4 0.4 2.5 2 0 0 2 2 2 0 Zinc-finger domain zf-C2H2_2 PF12756.7 KKK24615.1 - 0.83 10.0 12.7 0.58 10.5 2.9 3.4 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 KKK24615.1 - 3.3 8.8 23.1 1.5 9.9 1.7 5.1 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KKK24615.1 - 4.1 7.8 18.2 0.22 11.8 3.3 4.2 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding Ndc1_Nup PF09531.10 KKK24616.1 - 1.9e-173 578.5 0.3 2.1e-173 578.3 0.3 1.0 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup Syntaxin_2 PF14523.6 KKK24617.1 - 3.9e-25 88.2 2.9 3.9e-25 88.2 2.9 2.6 2 1 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.19 KKK24617.1 - 2.1e-13 50.0 1.6 2.1e-13 50.0 1.6 2.1 3 0 0 3 3 3 1 SNARE domain Syntaxin PF00804.25 KKK24617.1 - 4.9e-05 23.1 15.7 0.00011 22.0 15.7 1.6 1 1 0 1 1 1 1 Syntaxin Synaptobrevin PF00957.21 KKK24617.1 - 0.018 14.8 0.2 0.071 12.9 0.2 2.0 1 0 0 1 1 1 0 Synaptobrevin Vps23_core PF09454.10 KKK24617.1 - 0.068 13.1 0.9 0.28 11.2 0.1 2.3 3 0 0 3 3 3 0 Vps23 core domain Nre_C PF04895.12 KKK24617.1 - 0.19 11.6 0.2 0.19 11.6 0.2 2.2 2 0 0 2 2 2 0 Archaeal Nre, C-terminal DUF883 PF05957.13 KKK24617.1 - 0.72 10.5 0.1 0.72 10.5 0.1 3.2 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) SUIM_assoc PF16619.5 KKK24617.1 - 0.86 9.7 8.2 1.9 8.6 8.2 1.6 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 K_channel_TID PF07941.11 KKK24617.1 - 1.2 9.6 8.5 0.14 12.6 3.6 1.9 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain DUF1664 PF07889.12 KKK24617.1 - 4.3 7.4 6.7 20 5.2 1.5 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Cyto_heme_lyase PF01265.17 KKK24618.1 - 8.7e-40 137.1 2.0 3.5e-35 122.0 0.0 3.2 1 1 2 3 3 3 2 Cytochrome c/c1 heme lyase Rav1p_C PF12234.8 KKK24633.1 - 5.2e-282 937.0 0.0 6.5e-282 936.7 0.0 1.1 1 0 0 1 1 1 1 RAVE protein 1 C terminal WD40 PF00400.32 KKK24633.1 - 4.9e-05 24.0 0.9 0.039 14.8 0.0 4.5 4 0 0 4 4 4 1 WD domain, G-beta repeat 2-Hacid_dh_C PF02826.19 KKK24635.1 - 1.1e-32 112.8 0.0 6.2e-30 103.9 0.0 2.2 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KKK24635.1 - 1.4e-17 63.7 0.0 1.7e-17 63.3 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain OPT PF03169.15 KKK24636.1 - 5.9e-174 580.1 17.6 6.8e-174 579.9 17.6 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein SH3_9 PF14604.6 KKK24637.1 - 4e-10 39.4 0.0 6.3e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KKK24637.1 - 2.3e-07 30.3 0.0 4.1e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KKK24637.1 - 2.5e-06 27.0 0.0 5.9e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain DUF4064 PF13273.6 KKK24637.1 - 0.0076 16.5 0.5 0.016 15.5 0.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF4064) Peptidase_M56 PF05569.11 KKK24637.1 - 0.045 13.0 0.3 0.071 12.3 0.1 1.4 1 1 0 1 1 1 0 BlaR1 peptidase M56 Amnionless PF14828.6 KKK24637.1 - 0.052 12.4 0.3 0.069 12.0 0.3 1.1 1 0 0 1 1 1 0 Amnionless Melittin PF01372.17 KKK24637.1 - 0.095 12.7 0.4 0.24 11.4 0.4 1.7 1 0 0 1 1 1 0 Melittin Stevor PF17410.2 KKK24637.1 - 0.11 12.0 0.5 0.18 11.3 0.5 1.3 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame DUF3042 PF11240.8 KKK24637.1 - 0.25 11.4 2.8 2.1 8.5 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3042) DUF4448 PF14610.6 KKK24637.1 - 0.36 10.6 8.5 0.016 15.0 2.0 2.0 3 0 0 3 3 3 0 Protein of unknown function (DUF4448) Macoilin PF09726.9 KKK24637.1 - 0.76 8.3 5.7 1.1 7.8 5.7 1.1 1 0 0 1 1 1 0 Macoilin family RIFIN PF02009.16 KKK24637.1 - 7.4 6.4 9.9 23 4.8 10.1 1.5 1 1 0 1 1 1 0 Rifin Pkinase PF00069.25 KKK24638.1 - 4.5e-43 147.5 0.0 6.2e-43 147.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK24638.1 - 1.5e-16 60.5 0.0 2.2e-16 59.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase KIX_2 PF16987.5 KKK24638.1 - 0.00037 20.4 0.8 0.00064 19.7 0.8 1.4 1 0 0 1 1 1 1 KIX domain KIX PF02172.16 KKK24638.1 - 0.0012 19.0 0.4 0.0024 18.1 0.4 1.4 1 0 0 1 1 1 1 KIX domain APH PF01636.23 KKK24638.1 - 0.0017 18.4 0.1 0.6 10.0 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KKK24638.1 - 0.0019 17.0 0.0 0.0065 15.3 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 KKK24638.1 - 0.0049 16.2 0.0 0.058 12.7 0.0 2.1 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 KKK24638.1 - 0.019 14.6 0.0 0.13 11.8 0.0 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 KKK24638.1 - 0.047 13.0 0.1 0.12 11.7 0.0 1.7 2 0 0 2 2 2 0 Kinase-like WPP PF13943.6 KKK24638.1 - 0.15 12.5 2.8 0.27 11.7 1.6 2.1 2 0 0 2 2 2 0 WPP domain muHD PF10291.9 KKK24639.1 - 1.3e-93 313.3 0.4 1.7e-93 312.8 0.4 1.2 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain FCH PF00611.23 KKK24639.1 - 1.8e-08 34.5 0.3 8.7e-08 32.3 0.0 2.3 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain ALMS_repeat PF18727.1 KKK24639.1 - 0.074 13.0 0.6 0.23 11.4 0.6 1.8 1 0 0 1 1 1 0 Alstrom syndrome repeat MapZ_EC1 PF18041.1 KKK24639.1 - 0.13 12.5 1.0 1.3 9.3 0.4 2.5 2 0 0 2 2 2 0 MapZ extracellular domain 1 Sfi1 PF08457.10 KKK24640.1 - 7.4e-216 718.1 85.0 7.4e-216 718.1 85.0 2.1 1 1 1 2 2 2 2 Sfi1 spindle body protein NDUF_B7 PF05676.13 KKK24641.1 - 0.0011 18.7 1.4 0.51 10.1 0.4 2.1 1 1 1 2 2 2 2 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) CX9C PF16860.5 KKK24641.1 - 0.0018 18.3 0.8 0.0025 17.8 0.8 1.3 1 0 0 1 1 1 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Cmc1 PF08583.10 KKK24641.1 - 0.02 14.9 2.0 0.02 14.9 2.0 1.7 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.13 KKK24641.1 - 0.024 14.8 2.1 0.059 13.5 2.1 1.7 1 1 0 1 1 1 0 CHCH domain EPSP_synthase PF00275.20 KKK24642.1 - 3.3e-127 424.6 0.0 4.9e-127 424.1 0.0 1.2 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.20 KKK24642.1 - 9.3e-99 329.8 0.1 2e-98 328.7 0.0 1.6 2 0 0 2 2 2 1 3-dehydroquinate synthase DHquinase_I PF01487.15 KKK24642.1 - 1.1e-58 199.2 0.0 2.6e-58 198.0 0.0 1.7 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.22 KKK24642.1 - 1.2e-38 132.7 0.1 6.5e-38 130.3 0.0 2.1 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.11 KKK24642.1 - 1.9e-24 85.7 0.0 5e-24 84.4 0.0 1.8 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain SDH_C PF18317.1 KKK24642.1 - 4.8e-08 32.6 0.3 1.8e-07 30.8 0.1 2.1 2 0 0 2 2 2 1 Shikimate 5'-dehydrogenase C-terminal domain Fe-ADH_2 PF13685.6 KKK24642.1 - 5.2e-07 29.6 0.0 1.3e-06 28.3 0.0 1.7 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Shikimate_DH PF01488.20 KKK24642.1 - 0.00067 19.7 0.0 0.0016 18.5 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Fe-ADH PF00465.19 KKK24642.1 - 0.0094 14.8 0.4 0.027 13.3 0.4 1.7 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase AAA_18 PF13238.6 KKK24642.1 - 0.013 16.1 0.0 0.036 14.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KKK24642.1 - 0.11 12.2 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain tRNA-synt_1 PF00133.22 KKK24643.1 - 1.1e-153 512.7 0.0 1.8e-153 512.0 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KKK24643.1 - 1.1e-26 93.7 0.0 2.8e-26 92.3 0.0 1.7 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 KKK24643.1 - 1.3e-05 24.2 0.1 0.025 13.3 0.0 2.7 3 0 0 3 3 3 2 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 KKK24643.1 - 0.086 12.2 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain tRNA-synt_1 PF00133.22 KKK24644.1 - 2.5e-50 171.4 0.0 2.8e-50 171.2 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 KKK24644.1 - 1.3e-06 27.4 0.0 1.7e-06 27.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) Uso1_p115_head PF04869.14 KKK24645.1 - 2.1e-109 365.4 0.0 4.3e-109 364.4 0.0 1.6 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, head region Uso1_p115_C PF04871.13 KKK24645.1 - 1.6e-17 64.0 31.7 1.6e-17 64.0 31.7 4.7 1 1 3 4 4 4 2 Uso1 / p115 like vesicle tethering protein, C terminal region Filament PF00038.21 KKK24645.1 - 0.0012 18.6 50.3 0.01 15.4 15.1 2.9 1 1 1 2 2 2 2 Intermediate filament protein Tup_N PF08581.10 KKK24645.1 - 0.031 14.6 37.4 0.12 12.7 2.3 5.7 1 1 5 6 6 6 0 Tup N-terminal Lebercilin PF15619.6 KKK24645.1 - 0.04 13.6 56.0 0.1 12.3 30.7 3.7 1 1 2 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease Arm PF00514.23 KKK24645.1 - 0.062 13.4 0.7 24 5.1 0.0 4.2 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Nuc_N PF14448.6 KKK24645.1 - 0.11 12.3 1.1 0.34 10.8 0.2 2.3 2 0 0 2 2 2 0 Nuclease N terminal DUF3584 PF12128.8 KKK24645.1 - 0.13 9.8 55.6 0.055 11.0 22.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) HALZ PF02183.18 KKK24645.1 - 0.22 11.8 14.2 1.5 9.1 2.0 4.7 4 0 0 4 4 4 0 Homeobox associated leucine zipper Golgin_A5 PF09787.9 KKK24645.1 - 0.44 10.0 52.3 0.71 9.3 12.1 3.4 1 1 2 3 3 3 0 Golgin subfamily A member 5 Rab5-bind PF09311.11 KKK24645.1 - 1.4 8.2 47.3 1.4 8.2 36.6 3.1 1 1 2 3 3 3 0 Rabaptin-like protein Baculo_PEP_C PF04513.12 KKK24645.1 - 3.4 7.7 16.4 4 7.5 3.8 4.4 3 1 2 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus XRN_M PF17846.1 KKK24646.1 - 1.1e-149 499.2 2.8 1.2e-149 499.1 0.1 2.2 2 1 0 2 2 2 1 Xrn1 helical domain XRN_N PF03159.18 KKK24646.1 - 2.4e-101 338.2 0.4 2.4e-99 331.7 0.0 2.2 2 0 0 2 2 2 2 XRN 5'-3' exonuclease N-terminus zf-CCHC PF00098.23 KKK24646.1 - 0.085 13.0 2.3 0.15 12.2 2.3 1.4 1 0 0 1 1 1 0 Zinc knuckle Fungal_trans PF04082.18 KKK24656.1 - 1.2e-14 54.0 0.3 2.2e-14 53.1 0.3 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 KKK24656.1 - 5.7e-10 39.1 5.2 0.00012 22.3 0.1 3.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KKK24656.1 - 9.8e-07 28.9 1.3 9.8e-07 28.9 1.3 2.8 3 0 0 3 3 3 1 Zinc-finger double domain Zn_clus PF00172.18 KKK24656.1 - 9.2e-06 25.7 12.6 9.2e-06 25.7 12.6 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-met PF12874.7 KKK24656.1 - 7.1e-05 23.1 1.1 0.033 14.6 0.1 2.7 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KKK24656.1 - 0.0015 18.7 0.7 0.17 12.2 0.1 2.8 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 KKK24656.1 - 0.016 16.0 0.1 0.016 16.0 0.1 3.5 4 0 0 4 4 4 0 C2H2-type zinc finger zf-Di19 PF05605.12 KKK24656.1 - 0.093 13.0 1.8 0.21 11.9 1.8 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.6 KKK24656.1 - 0.33 11.0 2.0 1.7 8.7 0.1 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger LigB PF02900.18 KKK24657.1 - 1e-10 41.2 0.0 3.8e-09 36.0 0.0 2.0 2 0 0 2 2 2 2 Catalytic LigB subunit of aromatic ring-opening dioxygenase Nsp3_PL2pro PF12124.8 KKK24657.1 - 0.2 11.5 0.0 0.38 10.6 0.0 1.4 1 0 0 1 1 1 0 Coronavirus polyprotein cleavage domain Aldedh PF00171.22 KKK24658.1 - 5.4e-11 41.7 0.1 3.6e-06 25.8 0.0 2.3 2 0 0 2 2 2 2 Aldehyde dehydrogenase family MitoNEET_N PF10660.9 KKK24658.1 - 0.27 11.3 1.0 0.66 10.0 1.0 1.6 1 0 0 1 1 1 0 Iron-containing outer mitochondrial membrane protein N-terminus PepX_C PF08530.10 KKK24660.1 - 5.4e-44 150.8 0.1 9e-44 150.1 0.1 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Peptidase_S15 PF02129.18 KKK24660.1 - 2.9e-39 135.3 0.6 4e-39 134.8 0.6 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.8 KKK24660.1 - 0.0012 18.2 0.0 0.0021 17.4 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Methyltransf_23 PF13489.6 KKK24661.1 - 1.7e-20 73.5 0.0 2.3e-20 73.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KKK24661.1 - 1.8e-14 54.1 0.0 4.5e-14 52.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKK24661.1 - 3e-14 53.5 0.0 7.5e-14 52.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KKK24661.1 - 7.3e-11 42.1 0.0 1e-09 38.4 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KKK24661.1 - 2.1e-09 38.0 0.0 1.1e-08 35.7 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KKK24661.1 - 3.4e-07 29.8 0.0 0.0034 16.7 0.0 2.1 2 0 0 2 2 2 2 ubiE/COQ5 methyltransferase family CMAS PF02353.20 KKK24661.1 - 9.1e-05 21.9 0.0 0.00016 21.1 0.0 1.4 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.14 KKK24661.1 - 0.00015 21.3 0.0 0.0037 16.8 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_2 PF00891.18 KKK24661.1 - 0.002 17.5 0.0 0.011 15.1 0.0 1.9 2 0 0 2 2 2 1 O-methyltransferase domain FtsJ PF01728.19 KKK24661.1 - 0.012 15.8 0.0 0.035 14.2 0.0 1.7 1 1 1 2 2 2 0 FtsJ-like methyltransferase Methyltransf_4 PF02390.17 KKK24661.1 - 0.02 14.3 0.0 0.054 13.0 0.0 1.6 2 0 0 2 2 2 0 Putative methyltransferase PrmA PF06325.13 KKK24661.1 - 0.022 14.2 0.0 0.035 13.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.9 KKK24661.1 - 0.13 12.0 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase FAD_binding_3 PF01494.19 KKK24662.1 - 4e-26 92.1 1.2 1.2e-16 60.9 0.2 2.5 2 1 0 2 2 2 2 FAD binding domain FAD_binding_2 PF00890.24 KKK24662.1 - 0.0002 20.6 0.5 0.00035 19.8 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain PALP PF00291.25 KKK24662.1 - 0.0022 17.5 0.0 0.0038 16.7 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme TrkA_N PF02254.18 KKK24662.1 - 0.0025 18.1 0.1 0.0056 16.9 0.0 1.6 2 0 0 2 2 2 1 TrkA-N domain Pyr_redox_3 PF13738.6 KKK24662.1 - 0.0031 16.8 0.0 0.0055 16.0 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KKK24662.1 - 0.0038 17.4 0.0 0.015 15.6 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KKK24662.1 - 0.0057 15.9 0.0 0.1 11.8 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KKK24662.1 - 0.0086 15.7 1.2 0.021 14.4 0.2 1.9 2 2 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KKK24662.1 - 0.015 14.4 2.2 0.023 13.8 0.2 2.3 2 1 0 2 2 2 0 Lycopene cyclase protein Pyr_redox PF00070.27 KKK24662.1 - 0.015 15.8 0.0 0.13 12.8 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KKK24662.1 - 0.018 14.4 0.1 12 5.1 0.0 3.0 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase Thi4 PF01946.17 KKK24662.1 - 0.1 11.8 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Pho88 PF10032.9 KKK24663.1 - 1.1e-78 262.7 0.0 1.4e-78 262.4 0.0 1.1 1 0 0 1 1 1 1 Phosphate transport (Pho88) Histone PF00125.24 KKK24664.1 - 7.8e-17 61.9 0.0 1.1e-16 61.4 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 KKK24664.1 - 1.1e-11 44.3 0.0 2.4e-11 43.2 0.0 1.6 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 KKK24664.1 - 3.3e-05 24.1 0.0 4.8e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Gp_dh_C PF02800.20 KKK24665.1 - 2.6e-73 244.8 0.1 4e-73 244.2 0.1 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 KKK24665.1 - 2.4e-34 117.7 0.0 6.4e-34 116.3 0.0 1.7 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Apq12 PF12716.7 KKK24674.1 - 2.1e-19 69.2 14.9 3.6e-19 68.4 14.9 1.4 1 0 0 1 1 1 1 Nuclear pore assembly and biogenesis RNase_H PF00075.24 KKK24675.1 - 1.7e-23 83.4 0.0 2.2e-23 83.0 0.0 1.1 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.6 KKK24675.1 - 3.4e-05 23.7 0.0 0.17 11.7 0.0 2.2 2 0 0 2 2 2 2 Reverse transcriptase-like S-AdoMet_synt_C PF02773.16 KKK24676.1 - 2.3e-66 222.0 0.4 3e-65 218.4 0.0 2.1 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 KKK24676.1 - 5.1e-46 155.8 0.0 9.5e-46 154.9 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 KKK24676.1 - 6.1e-44 148.7 0.6 1.2e-43 147.7 0.1 1.8 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain Lactamase_B_3 PF13483.6 KKK24676.1 - 0.062 13.2 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 Beta-lactamase superfamily domain AdoMet_Synthase PF01941.19 KKK24676.1 - 0.07 11.9 0.2 0.72 8.6 0.1 2.0 1 1 1 2 2 2 0 S-adenosylmethionine synthetase (AdoMet synthetase) ATP_bind_1 PF03029.17 KKK24677.1 - 1.8e-77 260.4 0.0 3.2e-77 259.6 0.0 1.4 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_16 PF13191.6 KKK24677.1 - 6.1e-05 23.5 0.0 0.0088 16.4 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_14 PF13173.6 KKK24677.1 - 0.00039 20.5 0.0 0.001 19.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KKK24677.1 - 0.00073 19.9 0.2 0.025 14.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain CLP1_P PF16575.5 KKK24677.1 - 0.002 18.0 0.0 0.0064 16.3 0.0 1.8 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop RNA_helicase PF00910.22 KKK24677.1 - 0.0037 17.6 0.0 0.0093 16.3 0.0 1.7 1 0 0 1 1 1 1 RNA helicase AAA_22 PF13401.6 KKK24677.1 - 0.0071 16.6 0.0 0.022 15.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 KKK24677.1 - 0.0083 16.1 0.0 0.018 15.0 0.0 1.6 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 KKK24677.1 - 0.0095 15.7 0.0 0.023 14.4 0.0 1.7 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 KKK24677.1 - 0.01 14.9 0.0 0.019 14.0 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein NACHT PF05729.12 KKK24677.1 - 0.011 15.7 0.0 0.026 14.5 0.0 1.6 2 0 0 2 2 1 0 NACHT domain AAA PF00004.29 KKK24677.1 - 0.012 16.0 0.0 0.031 14.7 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) GTP_EFTU PF00009.27 KKK24677.1 - 0.012 15.1 0.1 1.8 8.0 0.1 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain ATPase_2 PF01637.18 KKK24677.1 - 0.013 15.5 0.0 0.062 13.2 0.0 1.9 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_7 PF12775.7 KKK24677.1 - 0.014 15.0 0.1 0.032 13.7 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region ABC_tran PF00005.27 KKK24677.1 - 0.017 15.6 0.0 0.17 12.4 0.0 2.1 2 0 0 2 2 2 0 ABC transporter AAA_30 PF13604.6 KKK24677.1 - 0.017 14.8 0.1 0.067 12.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KKK24677.1 - 0.017 15.6 0.0 0.046 14.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KKK24677.1 - 0.018 15.2 0.0 0.029 14.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain KAP_NTPase PF07693.14 KKK24677.1 - 0.019 14.3 0.0 0.038 13.2 0.0 1.5 1 1 0 1 1 1 0 KAP family P-loop domain AAA_17 PF13207.6 KKK24677.1 - 0.023 15.1 1.3 0.83 10.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 KKK24677.1 - 0.027 14.1 0.2 0.61 9.6 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 KKK24677.1 - 0.035 14.0 0.3 0.67 9.8 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase NTPase_1 PF03266.15 KKK24677.1 - 0.046 13.6 0.0 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 NTPase Septin PF00735.18 KKK24677.1 - 0.047 13.0 0.1 0.11 11.7 0.0 1.6 2 0 0 2 2 2 0 Septin PduV-EutP PF10662.9 KKK24677.1 - 0.056 13.2 0.0 1.2 8.8 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation SRP54 PF00448.22 KKK24677.1 - 0.059 13.0 0.0 0.15 11.7 0.0 1.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain NB-ARC PF00931.22 KKK24677.1 - 0.071 12.3 0.0 0.14 11.3 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain ATPase PF06745.13 KKK24677.1 - 0.091 12.1 0.0 0.25 10.7 0.0 1.7 2 0 0 2 2 2 0 KaiC CbiA PF01656.23 KKK24677.1 - 0.22 11.6 0.0 0.28 11.2 0.0 1.4 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain SLD3 PF08639.10 KKK24678.1 - 2.4e-161 538.2 4.1 4e-161 537.4 4.1 1.3 1 0 0 1 1 1 1 DNA replication regulator SLD3 MatP_C PF17414.2 KKK24679.1 - 0.2 11.9 4.3 0.25 11.6 0.9 3.0 3 0 0 3 3 3 0 MatP C-terminal ribbon-helix-helix domain MCC-bdg_PDZ PF10506.9 KKK24679.1 - 1.8 8.6 11.3 0.36 10.9 0.2 4.2 4 0 0 4 4 4 0 PDZ domain of MCC-2 bdg protein for Usher syndrome Cytochrom_C552 PF02335.15 KKK24679.1 - 3.5 6.4 7.2 0.54 9.1 2.9 1.7 2 0 0 2 2 2 0 Cytochrome c552 ADPRTs_Tse2 PF18648.1 KKK24680.1 - 0.03 14.4 0.0 0.13 12.3 0.0 2.0 2 0 0 2 2 2 0 Tse2 ADP-ribosyltransferase toxins bZIP_1 PF00170.21 KKK24699.1 - 0.0014 18.7 10.0 0.0055 16.8 10.0 1.9 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KKK24699.1 - 0.11 12.6 13.1 7.8 6.7 13.0 2.3 1 1 0 1 1 1 0 Basic region leucine zipper Hydin_ADK PF17213.3 KKK24699.1 - 4 7.7 5.8 6.9 6.9 5.8 1.5 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain SPRY PF00622.28 KKK24700.1 - 3.7e-19 69.0 0.1 1.3e-18 67.3 0.0 1.9 2 0 0 2 2 2 1 SPRY domain Amidase PF01425.21 KKK24701.1 - 1.4e-06 27.6 0.0 1.5e-06 27.4 0.0 1.0 1 0 0 1 1 1 1 Amidase PDEase_II PF02112.15 KKK24702.1 - 2.3e-53 181.5 0.0 9.4e-45 153.2 0.0 2.8 2 1 0 2 2 2 2 cAMP phosphodiesterases class-II Lactamase_B PF00753.27 KKK24702.1 - 0.0069 16.4 0.3 0.014 15.4 0.3 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KKK24702.1 - 0.08 12.5 0.1 0.15 11.5 0.1 1.4 1 0 0 1 1 1 0 Beta-lactamase superfamily domain GWT1 PF06423.12 KKK24703.1 - 1.6e-36 125.6 2.6 1.6e-36 125.6 2.6 2.1 2 1 0 2 2 2 1 GWT1 DUF4818 PF16089.5 KKK24703.1 - 0.024 15.1 1.8 0.073 13.5 0.0 2.8 2 1 0 3 3 3 0 Domain of unknown function (DUF4818) Amidase PF01425.21 KKK24704.1 - 8.9e-72 242.5 0.2 1.2e-71 242.0 0.2 1.1 1 0 0 1 1 1 1 Amidase Pkinase PF00069.25 KKK24705.1 - 2.2e-58 197.7 0.0 3.1e-58 197.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK24705.1 - 3.5e-25 88.8 0.0 4.9e-25 88.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KKK24705.1 - 4.1e-07 29.6 0.0 5.9e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KKK24705.1 - 0.0042 16.5 0.0 0.011 15.1 0.0 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KKK24705.1 - 0.042 13.8 0.0 0.45 10.4 0.0 2.3 2 0 0 2 2 2 0 Phosphotransferase enzyme family UQ_con PF00179.26 KKK24706.1 - 3.6e-50 169.2 0.0 4.4e-50 169.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KKK24706.1 - 3.4e-05 23.6 0.0 5.3e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 KKK24706.1 - 0.00025 21.3 0.1 0.00034 20.9 0.1 1.4 1 1 0 1 1 1 1 RWD domain UEV PF05743.13 KKK24706.1 - 0.0023 17.8 0.0 0.0034 17.2 0.0 1.4 1 0 0 1 1 1 1 UEV domain Med26_C PF15693.5 KKK24706.1 - 0.032 14.4 0.0 0.063 13.4 0.0 1.5 2 0 0 2 2 2 0 Mediator complex subunit 26 C-terminal A_deaminase PF00962.22 KKK24707.1 - 0.00019 20.9 0.0 0.0014 18.1 0.0 2.0 2 0 0 2 2 2 1 Adenosine/AMP deaminase Nucleos_tra2_C PF07662.13 KKK24708.1 - 1.5e-72 243.8 0.2 1.5e-72 243.8 0.2 2.7 3 0 0 3 3 3 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 KKK24708.1 - 8.8e-23 80.7 4.6 8.8e-23 80.7 4.6 2.5 2 0 0 2 2 2 1 Na+ dependent nucleoside transporter N-terminus Gate PF07670.14 KKK24708.1 - 0.0075 16.5 8.5 0.0075 16.5 8.5 3.5 4 1 1 5 5 5 1 Nucleoside recognition ATG2_CAD PF13329.6 KKK24709.1 - 5.2e-37 127.0 1.3 1.1e-36 125.9 0.1 2.1 2 0 0 2 2 2 1 Autophagy-related protein 2 CAD motif ATG_C PF09333.11 KKK24709.1 - 3.9e-27 94.4 0.0 1.4e-26 92.6 0.0 2.0 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain VPS13_C PF16909.5 KKK24709.1 - 0.11 12.3 0.1 0.46 10.2 0.0 2.1 2 0 0 2 2 2 0 Vacuolar-sorting-associated 13 protein C-terminal F-box-like PF12937.7 KKK24710.1 - 1.2e-07 31.5 0.1 2.4e-07 30.5 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KKK24710.1 - 1.7e-06 27.7 0.1 4.1e-06 26.5 0.0 1.7 2 0 0 2 2 2 1 F-box domain WD40 PF00400.32 KKK24711.1 - 1.9e-17 63.3 1.4 0.007 17.2 0.0 5.4 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKK24711.1 - 1.8e-06 28.2 0.0 0.0044 17.3 0.0 4.4 2 2 4 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KKK24711.1 - 0.0016 17.5 0.1 0.079 11.9 0.0 2.9 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KKK24711.1 - 0.033 13.5 0.0 0.059 12.7 0.0 1.4 1 0 0 1 1 1 0 WD40-like domain PXA PF02194.15 KKK24713.1 - 1.7e-49 168.3 0.4 8.5e-49 166.0 0.4 2.3 2 0 0 2 2 2 1 PXA domain Nexin_C PF08628.12 KKK24713.1 - 6.1e-25 88.0 0.0 2.1e-24 86.3 0.0 2.0 1 0 0 1 1 1 1 Sorting nexin C terminal PX PF00787.24 KKK24713.1 - 1.5e-21 76.5 0.5 3.6e-21 75.3 0.5 1.7 1 0 0 1 1 1 1 PX domain RGS PF00615.19 KKK24713.1 - 1.2e-11 44.9 0.1 2.9e-11 43.7 0.1 1.7 1 0 0 1 1 1 1 Regulator of G protein signaling domain RRP36 PF06102.12 KKK24713.1 - 0.0032 17.5 1.7 0.66 9.9 0.1 2.7 2 0 0 2 2 2 2 rRNA biogenesis protein RRP36 Mucin PF01456.17 KKK24713.1 - 1.3 9.0 24.9 3.2 7.7 24.9 1.6 1 0 0 1 1 1 0 Mucin-like glycoprotein adh_short PF00106.25 KKK24725.1 - 1.4e-12 47.5 0.0 1.9e-12 47.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KKK24725.1 - 3.9e-09 36.4 0.0 5e-09 36.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase F-box-like PF12937.7 KKK24726.1 - 0.0002 21.2 0.1 0.0002 21.2 0.1 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KKK24726.1 - 0.00022 21.0 0.0 0.00061 19.6 0.0 1.8 1 0 0 1 1 1 1 F-box domain PRANC PF09372.10 KKK24726.1 - 0.011 16.0 0.0 0.17 12.2 0.0 2.5 2 0 0 2 2 2 0 PRANC domain Band_7 PF01145.25 KKK24727.1 - 8.1e-28 97.6 3.4 8.1e-28 97.6 3.4 1.6 2 0 0 2 2 2 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 KKK24727.1 - 0.036 13.8 0.2 0.062 13.0 0.2 1.4 1 0 0 1 1 1 0 SPFH domain-Band 7 family EIF_2_alpha PF07541.12 KKK24728.1 - 6.5e-39 132.6 0.0 1.3e-38 131.6 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 KKK24728.1 - 8.3e-13 48.5 0.5 1.7e-12 47.5 0.5 1.6 1 0 0 1 1 1 1 S1 RNA binding domain PKD_channel PF08016.12 KKK24729.1 - 2.7e-06 26.4 22.8 2.8e-05 23.0 22.7 2.2 1 1 0 1 1 1 1 Polycystin cation channel MADF_DNA_bdg PF10545.9 KKK24729.1 - 0.0084 16.4 1.5 0.44 10.9 1.5 2.6 1 1 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like CENP-L PF13092.6 KKK24730.1 - 1.5e-41 142.4 0.0 2.3e-41 141.7 0.0 1.3 1 0 0 1 1 1 1 Kinetochore complex Sim4 subunit Fta1 Sulfate_transp PF00916.20 KKK24731.1 - 2.4e-55 187.9 16.0 1.8e-51 175.1 5.7 2.1 1 1 1 2 2 2 2 Sulfate permease family STAS PF01740.21 KKK24731.1 - 7.8e-16 57.8 0.0 1.3e-15 57.0 0.0 1.4 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 KKK24731.1 - 0.00021 21.6 0.0 0.00084 19.6 0.0 2.0 2 0 0 2 2 2 1 STAS domain PIRT PF15099.6 KKK24731.1 - 0.67 9.5 2.0 23 4.6 0.1 2.6 2 0 0 2 2 2 0 Phosphoinositide-interacting protein family Ribosomal_L6e PF01159.19 KKK24732.1 - 7.3e-39 132.8 0.3 1.3e-38 132.0 0.3 1.4 1 0 0 1 1 1 1 Ribosomal protein L6e AGP PF06376.12 KKK24732.1 - 0.1 12.5 0.3 0.35 10.7 0.2 1.9 2 0 0 2 2 2 0 Arabinogalactan peptide Proteasom_Rpn13 PF04683.13 KKK24733.1 - 1.6e-26 92.7 0.0 2.4e-26 92.1 0.0 1.3 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor RPN13_C PF16550.5 KKK24733.1 - 8.9e-13 48.4 1.6 1e-10 41.8 1.5 2.6 2 1 0 2 2 2 1 UCH-binding domain SNF2_N PF00176.23 KKK24744.1 - 2.7e-59 200.7 0.0 4.3e-59 200.0 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Chromo PF00385.24 KKK24744.1 - 4.2e-27 93.8 1.9 1.8e-17 63.0 0.6 3.0 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain DUF4208 PF13907.6 KKK24744.1 - 6.2e-23 81.1 0.9 2.5e-22 79.1 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4208) Helicase_C PF00271.31 KKK24744.1 - 1.2e-18 67.5 0.0 5.1e-18 65.4 0.0 2.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Cdh1_DBD_1 PF18196.1 KKK24744.1 - 4.5e-07 30.2 12.6 5.7e-05 23.4 0.7 4.1 2 1 1 3 3 3 2 Chromodomain helicase DNA-binding domain 1 ResIII PF04851.15 KKK24744.1 - 9e-07 29.1 0.0 2.4e-05 24.4 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 KKK24744.1 - 3.9e-05 23.0 0.0 0.00016 20.9 0.0 1.9 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 CHDCT2 PF08074.11 KKK24744.1 - 0.023 14.9 0.1 0.11 12.6 0.0 2.3 2 0 0 2 2 2 0 CHDCT2 (NUC038) domain CDH1_2_SANT_HL1 PF18375.1 KKK24744.1 - 1.7 9.4 8.9 1.3 9.7 1.3 3.4 2 0 0 2 2 2 0 CDH1/2 SANT-Helical linker 1 ABC_tran PF00005.27 KKK24745.1 - 1.8e-35 122.4 0.0 2.1e-16 60.7 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KKK24745.1 - 2.7e-10 40.6 5.6 0.12 12.2 0.0 4.4 2 2 2 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KKK24745.1 - 3.8e-10 39.6 2.1 0.0086 15.5 0.0 4.1 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain RLI PF04068.15 KKK24745.1 - 1.1e-06 28.3 1.6 1.1e-06 28.3 1.6 2.0 2 0 0 2 2 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI AAA_15 PF13175.6 KKK24745.1 - 2.4e-05 24.2 0.2 0.29 10.8 0.0 3.1 3 0 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 KKK24745.1 - 2.8e-05 24.4 0.0 0.0056 16.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 KKK24745.1 - 4e-05 24.0 0.0 0.041 14.3 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Fer4 PF00037.27 KKK24745.1 - 9e-05 22.1 2.5 9e-05 22.1 2.5 2.2 2 0 0 2 2 2 1 4Fe-4S binding domain Rad17 PF03215.15 KKK24745.1 - 9.6e-05 22.4 0.1 0.026 14.4 0.0 2.5 2 1 0 2 2 2 1 Rad17 P-loop domain AAA_16 PF13191.6 KKK24745.1 - 0.00014 22.2 0.0 0.25 11.7 0.0 2.5 2 1 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 KKK24745.1 - 0.00028 20.8 0.0 0.66 9.9 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_18 PF13238.6 KKK24745.1 - 0.00042 20.9 0.0 0.93 10.0 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KKK24745.1 - 0.0011 18.7 0.3 0.74 9.6 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_24 PF13479.6 KKK24745.1 - 0.0013 18.5 1.5 0.1 12.3 0.1 2.4 2 0 0 2 2 2 1 AAA domain Fer4_21 PF14697.6 KKK24745.1 - 0.0016 18.5 8.3 0.0039 17.3 8.3 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain AAA_13 PF13166.6 KKK24745.1 - 0.002 16.9 0.0 0.0045 15.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 KKK24745.1 - 0.0037 17.6 0.0 1.2 9.5 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_7 PF12775.7 KKK24745.1 - 0.0049 16.4 0.5 0.063 12.8 0.1 2.2 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_33 PF13671.6 KKK24745.1 - 0.0075 16.4 0.0 1.3 9.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 KKK24745.1 - 0.0076 16.8 1.3 1.1 9.8 0.5 2.8 3 0 0 3 3 2 1 AAA domain SRP54 PF00448.22 KKK24745.1 - 0.0087 15.7 2.7 0.19 11.3 0.1 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Fer4_6 PF12837.7 KKK24745.1 - 0.0096 16.0 2.2 0.0096 16.0 2.2 2.3 2 0 0 2 2 2 1 4Fe-4S binding domain NB-ARC PF00931.22 KKK24745.1 - 0.015 14.5 0.0 1.4 8.1 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain DLIC PF05783.11 KKK24745.1 - 0.017 14.0 0.0 0.031 13.1 0.0 1.3 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) AAA_28 PF13521.6 KKK24745.1 - 0.017 15.3 0.0 3.5 7.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 KKK24745.1 - 0.019 15.0 0.1 0.23 11.5 0.0 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Fer4_9 PF13187.6 KKK24745.1 - 0.022 14.9 8.9 0.051 13.7 8.9 1.6 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_10 PF13237.6 KKK24745.1 - 0.029 14.5 1.6 0.029 14.5 1.6 2.5 1 1 1 2 2 2 0 4Fe-4S dicluster domain NACHT PF05729.12 KKK24745.1 - 0.044 13.7 2.2 1.7 8.5 0.0 2.4 2 0 0 2 2 2 0 NACHT domain Fer4_8 PF13183.6 KKK24745.1 - 0.083 13.3 4.5 0.39 11.2 0.2 2.6 2 0 0 2 2 2 0 4Fe-4S dicluster domain AAA_14 PF13173.6 KKK24745.1 - 0.091 12.8 0.1 4.4 7.3 0.0 2.7 2 1 0 2 2 2 0 AAA domain Fer4_16 PF13484.6 KKK24745.1 - 0.093 13.7 0.2 0.093 13.7 0.2 2.8 2 0 0 2 2 2 0 4Fe-4S double cluster binding domain VirE PF05272.11 KKK24745.1 - 0.11 12.2 0.0 7.9 6.2 0.0 2.4 2 0 0 2 2 2 0 Virulence-associated protein E AAA_30 PF13604.6 KKK24745.1 - 0.12 12.0 1.2 6.2 6.5 0.0 2.6 2 1 0 2 2 2 0 AAA domain Thymidylate_kin PF02223.17 KKK24745.1 - 0.14 11.8 0.6 18 5.0 0.0 2.7 3 0 0 3 3 2 0 Thymidylate kinase ATPase PF06745.13 KKK24745.1 - 0.15 11.4 0.1 0.3 10.4 0.1 1.5 1 0 0 1 1 1 0 KaiC Fer4_7 PF12838.7 KKK24745.1 - 0.16 12.5 9.0 0.59 10.8 9.1 2.0 1 1 0 1 1 1 0 4Fe-4S dicluster domain PduV-EutP PF10662.9 KKK24745.1 - 0.17 11.6 2.1 0.21 11.3 0.1 2.2 2 0 0 2 2 1 0 Ethanolamine utilisation - propanediol utilisation Fer4_2 PF12797.7 KKK24745.1 - 3.8 7.8 7.6 0.31 11.2 1.2 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_17 PF13534.6 KKK24745.1 - 7 7.3 9.6 0.46 11.1 1.2 2.5 1 1 1 2 2 2 0 4Fe-4S dicluster domain PRA1 PF03208.19 KKK24755.1 - 4.3e-38 130.1 0.8 5.1e-38 129.9 0.8 1.0 1 0 0 1 1 1 1 PRA1 family protein TraS PF10624.9 KKK24755.1 - 0.11 12.4 2.0 0.68 9.8 0.3 2.1 2 0 0 2 2 2 0 Plasmid conjugative transfer entry exclusion protein TraS DUF2207 PF09972.9 KKK24755.1 - 0.23 10.2 1.6 0.29 9.9 1.6 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) SNF2_N PF00176.23 KKK24756.1 - 1.8e-56 191.4 0.6 2.9e-56 190.7 0.0 1.6 2 0 0 2 2 2 1 SNF2 family N-terminal domain zf-C3HC4_2 PF13923.6 KKK24756.1 - 7e-09 35.4 8.8 1.9e-08 34.0 8.8 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KKK24756.1 - 3.8e-08 33.1 8.6 9.1e-08 31.9 8.6 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KKK24756.1 - 9.7e-08 31.8 8.6 2.6e-07 30.4 8.6 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KKK24756.1 - 7.3e-07 29.4 11.2 1.9e-06 28.1 11.2 1.8 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 KKK24756.1 - 1e-06 28.5 7.2 2.1e-06 27.5 7.2 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 KKK24756.1 - 1.9e-05 24.6 4.6 2e-05 24.5 3.0 2.0 1 1 0 1 1 1 1 RING-type zinc-finger Helicase_C PF00271.31 KKK24756.1 - 2.4e-05 24.7 0.0 5.2e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-rbx1 PF12678.7 KKK24756.1 - 0.00045 20.4 8.0 0.0014 18.8 8.0 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KKK24756.1 - 0.0012 18.7 8.8 0.0031 17.4 8.8 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KKK24756.1 - 0.032 14.4 7.0 0.085 13.0 7.0 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING DUF1910 PF08928.10 KKK24756.1 - 0.055 13.5 1.0 0.16 12.0 1.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1910) YopE PF03545.13 KKK24756.1 - 0.15 12.2 0.4 4.2 7.6 0.0 2.8 2 0 0 2 2 2 0 Yersinia virulence determinant (YopE) Baculo_IE-1 PF05290.11 KKK24756.1 - 0.17 11.8 2.6 0.22 11.5 0.5 2.3 2 0 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) zf-P11 PF03854.14 KKK24756.1 - 0.78 9.5 8.0 2.1 8.1 8.0 1.8 1 0 0 1 1 1 0 P-11 zinc finger Zn_ribbon_17 PF17120.5 KKK24756.1 - 0.85 9.3 8.5 1.7 8.3 8.5 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_4 PF14570.6 KKK24756.1 - 1.1 9.1 5.5 3.4 7.5 5.5 1.8 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_10 PF16685.5 KKK24756.1 - 2.1 8.6 5.7 4.7 7.4 5.7 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 DZR PF12773.7 KKK24756.1 - 9.5 6.3 6.3 28 4.9 3.7 2.5 2 0 0 2 2 2 0 Double zinc ribbon PNGaseA PF12222.8 KKK24757.1 - 1.4e-188 627.2 0.3 2e-188 626.7 0.3 1.2 1 0 0 1 1 1 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A DUF1640 PF07798.11 KKK24757.1 - 2.1e-55 187.5 9.2 3.1e-55 186.9 9.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) Fungal_trans_2 PF11951.8 KKK24758.1 - 5.7e-14 51.7 1.2 8e-14 51.2 1.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Ecm29 PF13001.7 KKK24759.1 - 2.6e-155 517.9 0.0 8.3e-155 516.2 0.0 1.8 2 0 0 2 2 2 1 Proteasome stabiliser Adaptin_N PF01602.20 KKK24759.1 - 0.024 13.2 0.1 1.1 7.8 0.0 3.1 4 1 0 4 4 4 0 Adaptin N terminal region HEAT_2 PF13646.6 KKK24759.1 - 0.043 14.2 8.7 7.1 7.1 0.6 6.1 7 0 0 7 7 7 0 HEAT repeats WW PF00397.26 KKK24760.1 - 7.4e-12 45.1 0.6 1.6e-11 44.0 0.6 1.6 1 0 0 1 1 1 1 WW domain Exonuc_VII_L PF02601.15 KKK24760.1 - 0.23 11.0 13.7 0.35 10.4 13.7 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Frag1 PF10277.9 KKK24761.1 - 1e-41 142.9 11.0 1.1e-41 142.7 11.0 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family DUF645 PF04875.12 KKK24761.1 - 0.034 14.2 1.3 4.4 7.4 0.2 2.8 1 1 1 2 2 2 0 Protein of unknown function, DUF645 DnaJ PF00226.31 KKK24763.1 - 2.4e-09 37.2 0.8 2.2e-08 34.1 0.2 2.2 2 0 0 2 2 2 1 DnaJ domain Y_phosphatase3 PF13350.6 KKK24764.1 - 1.9e-20 73.8 0.0 6.8e-20 72.0 0.0 1.8 1 1 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 KKK24764.1 - 0.002 17.7 0.0 0.0032 17.1 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.13 KKK24764.1 - 0.0022 17.6 0.0 0.0035 16.9 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 KKK24764.1 - 0.013 15.3 0.0 0.026 14.4 0.0 1.4 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Myotub-related PF06602.14 KKK24764.1 - 0.15 11.0 0.0 0.22 10.4 0.0 1.2 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain PMM PF03332.13 KKK24766.1 - 6.1e-101 336.8 0.2 8e-101 336.4 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase DnaJ PF00226.31 KKK24766.1 - 6.3e-18 64.7 0.4 2.2e-17 62.9 0.1 2.0 2 0 0 2 2 2 1 DnaJ domain S6PP PF05116.13 KKK24766.1 - 0.005 16.4 0.0 1.7 8.1 0.0 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase_3 PF08282.12 KKK24766.1 - 0.011 15.6 0.0 0.049 13.4 0.0 1.9 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Bacteriocin_IIc PF10439.9 KKK24766.1 - 0.07 13.3 3.6 0.15 12.2 3.6 1.5 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide Gly-zipper_Omp PF13488.6 KKK24766.1 - 2.5 8.2 10.6 5.9 7.0 10.6 1.6 1 0 0 1 1 1 0 Glycine zipper G-patch PF01585.23 KKK24767.1 - 1.4e-10 40.9 1.7 3e-10 39.8 1.7 1.5 1 0 0 1 1 1 1 G-patch domain RRM_1 PF00076.22 KKK24767.1 - 0.00016 21.4 0.2 0.00047 19.9 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) G-patch_2 PF12656.7 KKK24767.1 - 0.0072 16.4 0.3 0.026 14.6 0.3 1.9 1 0 0 1 1 1 1 G-patch domain DUF5559 PF17714.1 KKK24767.1 - 0.11 12.4 1.4 0.28 11.0 1.4 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5559) UQ_con PF00179.26 KKK24768.1 - 1.8e-49 167.0 0.0 2.1e-49 166.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KKK24768.1 - 2.8e-05 23.8 0.0 3.2e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 KKK24768.1 - 0.059 13.7 0.9 0.07 13.4 0.9 1.5 1 1 0 1 1 1 0 RWD domain AMP-binding PF00501.28 KKK24769.1 - 9.3e-85 284.8 0.0 1.2e-84 284.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KKK24769.1 - 3.2e-16 60.1 0.0 1.3e-15 58.1 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain GH3 PF03321.13 KKK24769.1 - 0.0002 20.4 0.0 0.00042 19.3 0.0 1.4 2 0 0 2 2 2 1 GH3 auxin-responsive promoter Kdo PF06293.14 KKK24770.1 - 1.5e-07 31.0 0.1 2.2e-07 30.5 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 KKK24770.1 - 2.1e-07 30.6 0.1 2.8e-07 30.2 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KKK24770.1 - 8.5e-05 21.5 0.0 0.0001 21.2 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pkinase_Tyr PF07714.17 KKK24770.1 - 0.011 15.1 0.0 0.014 14.7 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase FTA2 PF13095.6 KKK24770.1 - 0.019 14.6 0.0 0.4 10.3 0.0 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 DUF3016 PF11454.8 KKK24770.1 - 0.13 12.0 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3016) DEAD PF00270.29 KKK24771.1 - 1.1e-41 142.6 0.2 1.9e-41 141.8 0.2 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KKK24771.1 - 1.3e-33 115.7 0.1 5.2e-33 113.7 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_30 PF13604.6 KKK24771.1 - 0.0015 18.3 0.0 0.0023 17.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KKK24771.1 - 0.0016 18.8 0.1 0.016 15.6 0.1 2.2 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 KKK24771.1 - 0.0042 17.1 0.0 0.0082 16.2 0.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.14 KKK24771.1 - 0.028 14.4 0.4 0.11 12.4 0.0 2.1 2 0 0 2 2 2 0 Flavivirus DEAD domain TniB PF05621.11 KKK24771.1 - 0.064 12.7 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein Helicase_RecD PF05127.14 KKK24771.1 - 0.1 12.4 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Helicase AAA_22 PF13401.6 KKK24771.1 - 0.18 12.1 1.0 0.82 9.9 1.0 2.0 1 1 0 1 1 1 0 AAA domain Aminotran_5 PF00266.19 KKK24772.1 - 5.2e-20 71.7 0.0 2.8e-13 49.6 0.0 2.4 2 0 0 2 2 2 2 Aminotransferase class-V MOSC_N PF03476.16 KKK24772.1 - 1.6e-10 40.9 0.0 3.2e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain DNA_ligase_A_M PF01068.21 KKK24773.1 - 4.4e-22 78.7 0.0 7.2e-22 78.0 0.0 1.3 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 KKK24773.1 - 5.9e-18 65.8 0.0 1e-17 65.0 0.0 1.4 1 0 0 1 1 1 1 DNA ligase N terminus DUF3449 PF11931.8 KKK24774.1 - 1e-74 250.4 1.6 1.3e-74 250.0 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3449) SF3A3 PF16837.5 KKK24774.1 - 1.8e-25 89.3 1.3 1.8e-25 89.3 1.3 2.0 2 0 0 2 2 2 1 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 SF3a60_bindingd PF12108.8 KKK24774.1 - 2e-14 53.2 0.9 4.8e-14 51.9 0.9 1.7 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain zf-met PF12874.7 KKK24774.1 - 4e-09 36.6 2.9 1.2e-07 31.9 1.3 2.4 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KKK24774.1 - 1e-08 35.2 1.5 1e-08 35.2 1.5 2.5 2 1 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KKK24774.1 - 0.0012 19.2 0.0 0.009 16.3 0.0 2.4 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-C4H2 PF10146.9 KKK24774.1 - 0.015 15.6 0.9 0.015 15.6 0.9 2.0 2 0 0 2 2 2 0 Zinc finger-containing protein zf-LYAR PF08790.11 KKK24774.1 - 0.084 12.8 0.2 0.21 11.5 0.2 1.7 1 0 0 1 1 1 0 LYAR-type C2HC zinc finger PRP9_N PF16958.5 KKK24774.1 - 0.19 11.7 23.6 0.03 14.4 3.0 3.6 4 1 1 5 5 5 0 Pre-mRNA-splicing factor PRP9 N-terminus zf-C2H2_4 PF13894.6 KKK24774.1 - 0.63 11.0 4.0 10 7.2 0.1 2.8 3 0 0 3 3 2 0 C2H2-type zinc finger zf-C2H2 PF00096.26 KKK24774.1 - 1.2 9.7 3.7 5.1 7.8 0.4 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type WD40 PF00400.32 KKK24776.1 - 1.2e-19 70.2 14.3 0.00084 20.1 0.2 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKK24776.1 - 6.5e-10 39.2 1.8 0.19 12.1 0.1 5.5 2 1 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KKK24776.1 - 0.00016 20.8 1.3 0.0085 15.1 0.8 2.9 2 1 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KKK24776.1 - 0.0079 14.9 0.2 0.018 13.7 0.2 1.5 1 0 0 1 1 1 1 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 KKK24776.1 - 0.021 13.4 0.0 0.49 8.9 0.0 2.3 2 0 0 2 2 2 0 Cytochrome D1 heme domain Frtz PF11768.8 KKK24776.1 - 0.18 10.1 0.1 0.36 9.1 0.1 1.4 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz ATP-synt_ab PF00006.25 KKK24777.1 - 5.6e-109 362.8 0.0 8.2e-109 362.2 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.5 KKK24777.1 - 1e-45 154.5 0.0 1.8e-45 153.7 0.0 1.4 1 0 0 1 1 1 1 ATPsynthase alpha/beta subunit N-term extension ATP-synt_ab_N PF02874.23 KKK24777.1 - 1.8e-15 57.2 1.9 3.7e-15 56.2 1.9 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain LPD23 PF18838.1 KKK24777.1 - 0.0076 16.0 0.1 0.014 15.1 0.1 1.4 1 0 0 1 1 1 1 Large polyvalent protein associated domain 23 NB-ARC PF00931.22 KKK24777.1 - 0.056 12.6 0.1 1.6 7.9 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain SPRY PF00622.28 KKK24778.1 - 0.041 14.0 0.0 6.8 6.8 0.0 2.6 2 0 0 2 2 2 0 SPRY domain Bystin PF05291.11 KKK24779.1 - 1.3e-131 438.2 0.0 1.7e-131 437.8 0.0 1.1 1 0 0 1 1 1 1 Bystin MTP18 PF10558.9 KKK24783.1 - 2.9e-75 251.9 0.0 4.4e-75 251.4 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) Git3 PF11710.8 KKK24787.1 - 2.4e-38 131.9 18.4 5.3e-38 130.8 18.4 1.5 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 GPR_Gpa2_C PF11970.8 KKK24787.1 - 1.2e-14 54.1 0.1 1.2e-14 54.1 0.1 2.2 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 C-term 7tm_1 PF00001.21 KKK24787.1 - 0.00023 20.6 11.9 0.00023 20.6 11.9 1.9 1 1 1 2 2 2 1 7 transmembrane receptor (rhodopsin family) Orf78 PF06024.12 KKK24787.1 - 7.1 7.0 5.8 3.8 7.9 0.1 3.0 3 0 0 3 3 3 0 Orf78 (ac78) PDZ_1 PF12812.7 KKK24788.1 - 3.6e-53 177.5 0.0 5.5e-34 116.0 0.0 2.5 2 0 0 2 2 2 2 PDZ-like domain Trypsin_2 PF13365.6 KKK24788.1 - 1.7e-26 93.9 0.7 2.6e-22 80.3 0.0 2.9 3 0 0 3 3 3 2 Trypsin-like peptidase domain PDZ_6 PF17820.1 KKK24788.1 - 9.2e-21 73.4 0.7 6.4e-09 35.5 0.5 4.7 4 1 0 4 4 4 3 PDZ domain PDZ_2 PF13180.6 KKK24788.1 - 8.2e-13 48.5 0.1 5.6e-05 23.4 0.0 4.3 5 0 0 5 5 5 3 PDZ domain PDZ PF00595.24 KKK24788.1 - 9.9e-12 45.1 0.0 8.7e-05 22.8 0.0 3.6 3 0 0 3 3 3 3 PDZ domain Tricorn_PDZ PF14685.6 KKK24788.1 - 0.00029 20.7 0.5 0.24 11.4 0.2 3.8 3 0 0 3 3 3 1 Tricorn protease PDZ domain 4HPAD_g_N PF18671.1 KKK24788.1 - 0.069 12.9 0.0 0.26 11.0 0.0 2.0 1 0 0 1 1 1 0 4-Hydroxyphenylacetate decarboxylase subunit gamma N-terminal Peptidase_S46 PF10459.9 KKK24788.1 - 0.076 11.6 0.1 0.15 10.7 0.1 1.3 1 0 0 1 1 1 0 Peptidase S46 Pup PF05639.11 KKK24788.1 - 0.13 13.1 0.0 1.1 10.3 0.0 2.3 2 0 0 2 2 2 0 Pup-like protein DUF31 PF01732.16 KKK24788.1 - 0.16 11.5 0.3 0.23 10.9 0.3 1.2 1 0 0 1 1 1 0 Putative peptidase (DUF31) Cyclase PF04199.13 KKK24789.1 - 2.2e-11 44.2 0.0 3.6e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 Putative cyclase SSXT PF05030.12 KKK24790.1 - 1.3e-05 24.7 0.0 0.21 11.3 0.0 2.3 2 0 0 2 2 2 2 SSXT protein (N-terminal region) DUF1179 PF06678.11 KKK24790.1 - 5.6 7.0 7.0 6.5 6.8 3.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1179) DUF155 PF02582.14 KKK24791.1 - 1.1e-53 182.0 0.0 1.7e-53 181.4 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Occludin_ELL PF07303.13 KKK24792.1 - 0.34 11.7 4.7 0.45 11.3 1.2 2.5 2 0 0 2 2 2 0 Occludin homology domain Yuri_gagarin PF15934.5 KKK24792.1 - 1 9.2 5.0 0.18 11.6 0.6 1.9 2 0 0 2 2 2 0 Yuri gagarin Acetyltransf_1 PF00583.25 KKK24794.1 - 5.4e-05 23.4 0.0 0.00011 22.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KKK24794.1 - 0.0012 19.2 0.0 0.0028 18.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KKK24794.1 - 0.059 13.3 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Arf PF00025.21 KKK24795.1 - 1.1e-57 194.3 2.4 2.8e-56 189.7 0.2 2.0 2 0 0 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 KKK24795.1 - 2.9e-09 37.2 0.0 4.4e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KKK24795.1 - 3.8e-09 36.3 0.0 4.7e-09 36.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 KKK24795.1 - 1.3e-07 31.2 0.0 1.7e-07 30.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 KKK24795.1 - 3.4e-07 29.8 2.4 4.9e-06 26.0 0.8 2.6 1 1 1 2 2 2 1 G-protein alpha subunit MMR_HSR1 PF01926.23 KKK24795.1 - 7.1e-06 26.1 0.0 1.1e-05 25.5 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 KKK24795.1 - 4.4e-05 23.0 0.0 6e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 KKK24795.1 - 5.2e-05 22.9 0.0 0.00044 19.8 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain HCV_NS1 PF01560.17 KKK24795.1 - 0.042 12.5 0.0 0.048 12.3 0.0 1.1 1 0 0 1 1 1 0 Hepatitis C virus non-structural protein E2/NS1 cobW PF02492.19 KKK24795.1 - 0.06 12.9 0.0 1.3 8.6 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain HMGL-like PF00682.19 KKK24796.1 - 3.9e-79 265.9 0.0 5.7e-79 265.4 0.0 1.2 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.10 KKK24796.1 - 1.8e-21 76.4 0.0 3.8e-21 75.4 0.0 1.6 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain DEAD PF00270.29 KKK24797.1 - 1.5e-46 158.4 0.8 2.2e-46 157.8 0.1 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KKK24797.1 - 4e-31 107.6 0.2 4e-29 101.2 0.1 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain UTP25 PF06862.12 KKK24797.1 - 0.00087 18.2 1.4 0.0074 15.1 0.1 3.0 2 1 1 3 3 3 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Zn_clus PF00172.18 KKK24798.1 - 2.3e-08 34.0 14.3 4.8e-08 33.0 14.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ALO PF04030.14 KKK24799.1 - 6.8e-91 304.7 0.3 8.9e-91 304.3 0.3 1.1 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.23 KKK24799.1 - 4.8e-34 117.1 0.5 7e-34 116.5 0.5 1.3 1 0 0 1 1 1 1 FAD binding domain DUF4045 PF13254.6 KKK24800.1 - 6.5e-135 451.0 34.3 6.5e-135 451.0 34.3 5.2 3 2 0 5 5 5 1 Domain of unknown function (DUF4045) Gelsolin PF00626.22 KKK24800.1 - 7e-11 41.9 0.0 2.9e-05 23.9 0.0 3.6 3 0 0 3 3 3 3 Gelsolin repeat MIF4G PF02854.19 KKK24801.1 - 1.1e-49 169.0 0.0 1.1e-49 169.0 0.0 1.9 2 0 0 2 2 2 1 MIF4G domain eIF_4G1 PF12152.8 KKK24801.1 - 3.2e-24 84.9 0.5 9.4e-24 83.4 0.5 1.9 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 Usp PF00582.26 KKK24802.1 - 2.9e-24 86.2 0.0 5.2e-24 85.4 0.0 1.4 1 0 0 1 1 1 1 Universal stress protein family Pkinase PF00069.25 KKK24803.1 - 0.0012 18.2 0.0 0.0028 17.1 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK24803.1 - 0.0053 16.1 0.0 0.02 14.2 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase TrkH PF02386.16 KKK24804.1 - 2.4e-118 395.7 4.2 4.6e-118 394.8 1.6 2.0 2 0 0 2 2 2 1 Cation transport protein SelP_N PF04592.14 KKK24804.1 - 0.39 10.1 8.4 0.6 9.5 8.4 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region HemY_N PF07219.13 KKK24804.1 - 0.4 10.9 4.5 3.4 7.9 0.2 3.2 2 0 0 2 2 2 0 HemY protein N-terminus SR-25 PF10500.9 KKK24805.1 - 0.035 13.7 0.8 0.052 13.2 0.8 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Cytomega_TRL10 PF06084.11 KKK24805.1 - 2.5 8.1 7.2 0.79 9.7 3.1 2.1 2 0 0 2 2 2 0 Cytomegalovirus TRL10 protein Metallophos_C PF14008.6 KKK24806.1 - 2.9e-10 40.9 0.6 3.8e-09 37.3 0.6 2.6 1 1 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C Pur_ac_phosph_N PF16656.5 KKK24806.1 - 3.4e-06 27.5 0.3 0.0029 18.2 0.0 2.4 1 1 1 2 2 2 2 Purple acid Phosphatase, N-terminal domain Metallophos PF00149.28 KKK24806.1 - 2.9e-05 24.7 0.9 0.00049 20.6 0.0 2.4 1 1 2 3 3 3 1 Calcineurin-like phosphoesterase PhoD PF09423.10 KKK24806.1 - 0.12 11.4 0.0 6.3 5.7 0.0 2.1 2 0 0 2 2 2 0 PhoD-like phosphatase Methyltransf_2 PF00891.18 KKK24807.1 - 1.4e-21 76.8 0.0 2.6e-21 75.9 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase domain HTH_Crp_2 PF13545.6 KKK24807.1 - 0.19 11.8 0.0 0.39 10.7 0.0 1.5 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain AA_permease_2 PF13520.6 KKK24808.1 - 8.1e-43 146.8 29.5 2.1e-25 89.4 17.3 2.1 1 1 1 2 2 2 2 Amino acid permease SLC35F PF06027.12 KKK24809.1 - 5.1e-92 308.6 26.8 5.9e-92 308.4 26.8 1.0 1 0 0 1 1 1 1 Solute carrier family 35 CRT-like PF08627.10 KKK24809.1 - 2.5e-08 33.3 5.9 4.5e-08 32.4 5.9 1.5 1 0 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like EamA PF00892.20 KKK24809.1 - 5.3e-05 23.4 37.6 0.014 15.5 15.9 2.3 2 1 0 2 2 2 2 EamA-like transporter family GPI-anchored PF10342.9 KKK24810.1 - 2.8e-24 85.7 0.1 2.8e-24 85.7 0.1 2.2 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Methyltransf_25 PF13649.6 KKK24811.1 - 2.3e-16 60.2 0.0 5.2e-16 59.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KKK24811.1 - 1.1e-15 58.0 0.0 3.4e-15 56.5 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KKK24811.1 - 6.3e-13 49.3 0.0 1.1e-12 48.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KKK24811.1 - 1.5e-10 41.1 0.0 2.5e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KKK24811.1 - 6.5e-08 32.6 0.0 2.6e-07 30.6 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.20 KKK24811.1 - 0.0059 15.9 0.0 0.0089 15.3 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.14 KKK24811.1 - 0.12 11.9 0.0 0.4 10.2 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_9 PF08003.11 KKK24811.1 - 0.22 10.4 0.0 0.31 9.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) p450 PF00067.22 KKK24812.1 - 3.5e-55 187.6 0.0 1.5e-54 185.5 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 ketoacyl-synt PF00109.26 KKK24813.1 - 2.2e-76 256.8 0.5 6.7e-76 255.2 0.5 2.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 KKK24813.1 - 1.5e-37 128.2 0.1 5.3e-37 126.4 0.1 2.0 2 0 0 2 2 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.25 KKK24813.1 - 3.4e-33 113.8 4.5 5.4e-16 58.7 0.7 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site PS-DH PF14765.6 KKK24813.1 - 8.8e-27 94.1 0.0 1.6e-26 93.2 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase HTH_51 PF18558.1 KKK24813.1 - 6.3e-25 86.9 0.1 6.4e-24 83.6 0.1 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain Acyl_transf_1 PF00698.21 KKK24813.1 - 5.2e-20 72.2 0.0 2.6e-19 69.9 0.0 2.0 2 0 0 2 2 2 1 Acyl transferase domain Methyltransf_12 PF08242.12 KKK24813.1 - 9.7e-19 68.0 0.0 3e-18 66.4 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Abhydrolase_3 PF07859.13 KKK24813.1 - 3.9e-14 53.0 0.0 8.9e-11 42.0 0.0 2.6 2 0 0 2 2 2 2 alpha/beta hydrolase fold Methyltransf_25 PF13649.6 KKK24813.1 - 2.6e-12 47.3 0.0 1.1e-11 45.2 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KKK24813.1 - 9.9e-12 45.0 0.0 3.5e-11 43.2 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KKK24813.1 - 6.4e-11 42.8 0.0 3.8e-10 40.3 0.0 2.5 2 0 0 2 2 1 1 Methyltransferase domain SAT PF16073.5 KKK24813.1 - 6.8e-10 39.1 5.1 1.4e-07 31.5 0.4 3.2 2 1 0 2 2 2 2 Starter unit:ACP transacylase in aflatoxin biosynthesis Peptidase_S9 PF00326.21 KKK24813.1 - 7.7e-10 38.6 0.0 3.5e-07 29.9 0.0 2.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family Methyltransf_31 PF13847.6 KKK24813.1 - 1.6e-09 37.7 0.0 9e-09 35.3 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 KKK24813.1 - 2.7e-09 37.5 0.1 1.4e-08 35.1 0.1 2.2 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension Abhydrolase_6 PF12697.7 KKK24813.1 - 3.1e-06 27.9 5.5 5.4e-05 23.9 1.5 2.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Thiolase_N PF00108.23 KKK24813.1 - 1.2e-05 24.9 0.2 2.5e-05 23.8 0.2 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain DLH PF01738.18 KKK24813.1 - 6e-05 22.7 0.0 0.0013 18.3 0.0 2.5 2 0 0 2 2 2 1 Dienelactone hydrolase family Methyltransf_33 PF10017.9 KKK24813.1 - 0.0003 20.1 0.0 0.0021 17.2 0.0 2.2 2 0 0 2 2 2 1 Histidine-specific methyltransferase, SAM-dependent Ubie_methyltran PF01209.18 KKK24813.1 - 0.00053 19.4 0.0 0.0013 18.1 0.0 1.6 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Hydrolase_4 PF12146.8 KKK24813.1 - 0.00057 19.2 0.1 0.007 15.7 0.0 2.7 3 0 0 3 3 3 1 Serine aminopeptidase, S33 Methyltransf_28 PF02636.17 KKK24813.1 - 0.0013 18.4 0.0 0.0025 17.5 0.0 1.5 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_16 PF10294.9 KKK24813.1 - 0.0071 16.1 0.0 0.018 14.8 0.0 1.6 1 0 0 1 1 1 1 Lysine methyltransferase Abhydrolase_2 PF02230.16 KKK24813.1 - 0.039 13.8 0.0 4.1 7.1 0.0 2.7 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Peptidase_S15 PF02129.18 KKK24813.1 - 0.069 12.7 0.0 0.52 9.9 0.0 2.3 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) COesterase PF00135.28 KKK24813.1 - 0.077 11.8 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 Carboxylesterase family LIP PF03583.14 KKK24813.1 - 0.092 12.1 0.0 0.21 10.9 0.0 1.5 1 0 0 1 1 1 0 Secretory lipase GMC_oxred_N PF00732.19 KKK24814.1 - 2.2e-55 188.1 0.0 3.1e-55 187.6 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KKK24814.1 - 2.7e-32 112.3 0.0 6.3e-32 111.1 0.0 1.7 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_3 PF13738.6 KKK24814.1 - 4.1e-09 36.1 0.1 0.0019 17.5 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KKK24814.1 - 1.3e-05 24.3 0.2 2.3e-05 23.5 0.2 1.3 1 0 0 1 1 1 1 Tryptophan halogenase FAD_binding_2 PF00890.24 KKK24814.1 - 1.3e-05 24.4 1.7 0.0077 15.4 0.3 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 KKK24814.1 - 1.7e-05 24.6 0.5 0.00053 19.7 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KKK24814.1 - 0.00011 21.5 0.4 0.0013 17.8 0.2 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KKK24814.1 - 0.00016 21.0 0.1 0.00061 19.1 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KKK24814.1 - 0.00028 20.2 0.1 0.0019 17.5 0.0 2.0 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.6 KKK24814.1 - 0.00071 19.8 0.1 0.0021 18.3 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KKK24814.1 - 0.02 14.9 0.1 0.049 13.6 0.1 1.7 1 0 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox PF00070.27 KKK24814.1 - 0.11 13.1 0.3 0.59 10.7 0.1 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KKK24814.1 - 0.13 10.9 0.1 0.22 10.2 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein TrkA_N PF02254.18 KKK24814.1 - 0.2 11.9 0.3 0.45 10.8 0.3 1.6 1 0 0 1 1 1 0 TrkA-N domain ketoacyl-synt PF00109.26 KKK24815.1 - 4.9e-63 213.1 0.0 1.1e-62 211.9 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 KKK24815.1 - 1e-60 204.7 1.1 2.5e-60 203.5 0.2 2.1 2 0 0 2 2 2 1 KR domain PS-DH PF14765.6 KKK24815.1 - 2.6e-53 181.2 0.0 7.3e-53 179.7 0.0 1.8 2 0 0 2 2 2 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 KKK24815.1 - 6.6e-50 170.4 0.1 2.1e-49 168.8 0.1 1.9 1 1 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KKK24815.1 - 1.9e-39 134.3 0.0 6.1e-39 132.7 0.0 2.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N_2 PF13602.6 KKK24815.1 - 2.2e-16 61.1 0.0 6.9e-15 56.3 0.0 3.4 3 0 0 3 3 3 1 Zinc-binding dehydrogenase KAsynt_C_assoc PF16197.5 KKK24815.1 - 1.8e-14 54.1 0.0 6.8e-14 52.3 0.0 2.0 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension adh_short PF00106.25 KKK24815.1 - 5.9e-14 52.0 2.0 4.9e-13 49.0 0.3 2.7 2 0 0 2 2 2 1 short chain dehydrogenase ADH_zinc_N PF00107.26 KKK24815.1 - 1.1e-12 48.0 0.0 5.3e-12 45.9 0.1 2.2 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.12 KKK24815.1 - 2.5e-12 47.4 0.0 4.2e-11 43.5 0.0 3.1 4 0 0 4 4 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KKK24815.1 - 6.6e-12 45.6 0.0 1.5e-11 44.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain adh_short_C2 PF13561.6 KKK24815.1 - 7.3e-08 32.3 0.6 3.3e-07 30.1 0.1 2.3 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Sacchrp_dh_NADP PF03435.18 KKK24815.1 - 8e-06 26.1 0.0 0.058 13.7 0.0 2.7 2 0 0 2 2 2 2 Saccharopine dehydrogenase NADP binding domain PP-binding PF00550.25 KKK24815.1 - 8e-06 26.1 1.4 1.3e-05 25.4 0.2 2.0 2 0 0 2 2 1 1 Phosphopantetheine attachment site Methyltransf_31 PF13847.6 KKK24815.1 - 2.3e-05 24.2 0.0 9.9e-05 22.2 0.0 2.1 2 1 0 2 2 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKK24815.1 - 3.9e-05 24.3 0.1 0.00062 20.4 0.0 3.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KKK24815.1 - 6.4e-05 23.5 0.1 0.00067 20.3 0.0 2.8 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 KKK24815.1 - 7.8e-05 22.1 0.0 0.00019 20.8 0.0 1.6 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.9 KKK24815.1 - 0.00041 20.1 0.0 0.0014 18.4 0.0 1.8 2 0 0 2 2 2 1 Lysine methyltransferase ADH_N PF08240.12 KKK24815.1 - 0.0015 18.4 0.2 0.0046 16.8 0.2 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain GDP_Man_Dehyd PF16363.5 KKK24815.1 - 0.044 13.2 0.0 0.076 12.4 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Thiolase_N PF00108.23 KKK24815.1 - 0.057 12.8 0.1 0.14 11.5 0.1 1.6 1 0 0 1 1 1 0 Thiolase, N-terminal domain Fungal_trans PF04082.18 KKK24816.1 - 1e-10 41.1 0.0 2e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK24816.1 - 5.5e-09 36.0 11.2 1e-08 35.1 11.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Myb_DNA-binding PF00249.31 KKK24817.1 - 2.9e-34 117.0 12.2 3.5e-12 46.3 0.8 3.8 4 0 0 4 4 4 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KKK24817.1 - 1.3e-24 86.2 5.2 6.3e-08 32.8 0.1 3.4 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 KKK24817.1 - 0.001 18.9 0.0 0.38 10.7 0.0 2.5 2 0 0 2 2 2 2 Myb DNA-binding like MADF_DNA_bdg PF10545.9 KKK24817.1 - 0.22 11.8 1.7 8.6 6.8 0.1 2.9 3 0 0 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Lactamase_B PF00753.27 KKK24818.1 - 1.2e-08 35.3 0.9 1.6e-07 31.5 0.9 2.2 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KKK24818.1 - 0.00085 18.9 0.1 0.0016 18.0 0.1 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Phosphoesterase PF04185.14 KKK24819.1 - 8.2e-23 81.2 6.4 2e-22 79.9 2.2 2.5 1 1 1 2 2 2 2 Phosphoesterase family YopD PF05844.12 KKK24819.1 - 0.13 11.2 0.1 0.25 10.3 0.1 1.3 1 0 0 1 1 1 0 YopD protein Sugar_tr PF00083.24 KKK24820.1 - 2.7e-26 92.4 23.9 3.5e-17 62.4 6.4 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KKK24820.1 - 1.5e-14 53.7 36.2 6e-08 32.0 19.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KKK24821.1 - 1.4e-22 80.2 26.2 1.5e-20 73.5 26.2 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKK24821.1 - 3.9e-06 26.0 37.8 6.2e-05 22.1 11.5 3.1 1 1 2 3 3 2 2 Major Facilitator Superfamily DUF2333 PF10095.9 KKK24821.1 - 0.11 11.5 0.0 0.19 10.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2333) Transferase PF02458.15 KKK24822.1 - 1.3e-17 63.6 0.0 7.7e-15 54.5 0.0 2.5 2 1 0 2 2 2 2 Transferase family CIA30 PF08547.12 KKK24824.1 - 1.5e-40 138.9 0.0 1.8e-40 138.6 0.0 1.1 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) Amino_oxidase PF01593.24 KKK24825.1 - 1.1e-49 170.0 0.2 2.3e-33 116.2 0.0 2.1 1 1 1 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KKK24825.1 - 1.6e-15 57.1 0.2 3.2e-15 56.1 0.2 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KKK24825.1 - 9.2e-08 31.7 0.0 1.7e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KKK24825.1 - 2.8e-06 26.3 0.4 4e-06 25.8 0.4 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.27 KKK24825.1 - 2.8e-06 27.8 0.2 7.1e-06 26.5 0.2 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KKK24825.1 - 4.5e-06 26.0 0.0 6.7e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.19 KKK24825.1 - 1.7e-05 24.2 1.8 2.6e-05 23.7 1.2 1.5 1 1 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.21 KKK24825.1 - 2.3e-05 23.8 0.1 3.7e-05 23.1 0.1 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.7 KKK24825.1 - 5.4e-05 22.7 0.0 7.2e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.24 KKK24825.1 - 0.00012 21.8 2.8 0.00018 21.2 2.8 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 KKK24825.1 - 0.00052 19.2 0.7 0.00078 18.6 0.7 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Thi4 PF01946.17 KKK24825.1 - 0.00077 18.8 0.1 0.002 17.4 0.1 1.6 2 0 0 2 2 2 1 Thi4 family Glu_dehyd_C PF16912.5 KKK24825.1 - 0.0027 17.2 0.0 0.0053 16.3 0.0 1.4 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus Lycopene_cycl PF05834.12 KKK24825.1 - 0.012 14.7 0.4 0.017 14.2 0.4 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein 3HCDH_N PF02737.18 KKK24825.1 - 0.018 14.9 0.0 0.028 14.3 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.6 KKK24825.1 - 0.035 13.3 0.0 0.055 12.7 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KKK24825.1 - 0.051 12.4 0.4 0.088 11.6 0.4 1.3 1 0 0 1 1 1 0 Tryptophan halogenase YjeF_N PF03853.15 KKK24825.1 - 0.09 12.7 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 YjeF-related protein N-terminus DUF1188 PF06690.11 KKK24825.1 - 0.099 12.2 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1188) Shikimate_DH PF01488.20 KKK24825.1 - 0.13 12.3 0.3 0.32 11.0 0.1 1.8 2 0 0 2 2 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 KKK24825.1 - 0.14 12.6 1.6 0.19 12.2 0.6 1.9 2 1 0 2 2 1 0 Putative NAD(P)-binding ApbA PF02558.16 KKK24825.1 - 0.23 11.1 0.2 0.42 10.2 0.2 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA MFS_1 PF07690.16 KKK24826.1 - 6.1e-31 107.6 18.8 6.1e-31 107.6 18.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily YpmT PF17431.2 KKK24826.1 - 0.8 9.8 2.8 1.1 9.4 0.0 2.7 2 1 1 3 3 3 0 Uncharacterized YmpT-like PAP2_3 PF14378.6 KKK24827.1 - 3.4e-29 101.9 18.6 8.5e-23 81.0 4.5 2.5 2 0 0 2 2 2 2 PAP2 superfamily ABC2_membrane_2 PF12679.7 KKK24827.1 - 0.16 11.2 3.9 0.3 10.3 3.9 1.5 1 0 0 1 1 1 0 ABC-2 family transporter protein Sugar_tr PF00083.24 KKK24828.1 - 3.1e-31 108.7 16.7 1.1e-19 70.6 0.8 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KKK24828.1 - 2.2e-14 53.1 70.6 1.4e-13 50.5 41.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily ATG22 PF11700.8 KKK24828.1 - 0.011 14.4 12.0 0.37 9.4 0.2 3.4 3 0 0 3 3 3 0 Vacuole effluxer Atg22 like MFS_1 PF07690.16 KKK24829.1 - 8e-41 140.1 43.0 8e-41 140.1 43.0 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KKK24829.1 - 2.6e-14 52.6 14.2 3.9e-14 52.0 8.0 2.0 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) DUF3572 PF12096.8 KKK24829.1 - 0.13 12.5 0.1 19 5.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3572) p450 PF00067.22 KKK24830.1 - 8.3e-46 156.7 0.0 1.2e-45 156.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Myb_DNA-binding PF00249.31 KKK24831.1 - 8.8e-34 115.5 15.3 5e-12 45.8 3.5 3.3 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KKK24831.1 - 7e-27 93.5 8.6 4.7e-10 39.6 3.0 3.3 2 1 1 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 KKK24831.1 - 0.0011 18.8 1.5 0.11 12.4 0.0 2.6 3 0 0 3 3 3 1 Myb DNA-binding like SANT_DAMP1_like PF16282.5 KKK24831.1 - 0.032 14.4 1.4 2.7 8.3 0.1 2.5 1 1 1 2 2 2 0 SANT/Myb-like domain of DAMP1 SLIDE PF09111.10 KKK24831.1 - 0.057 13.4 0.1 3 7.9 0.0 2.6 1 1 1 2 2 2 0 SLIDE Rap1_C PF11626.8 KKK24831.1 - 0.33 11.1 5.2 0.66 10.1 1.1 2.9 2 1 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain MADF_DNA_bdg PF10545.9 KKK24831.1 - 0.8 10.1 9.4 11 6.4 1.4 3.3 3 0 0 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like NACHT PF05729.12 KKK24833.1 - 1.2e-06 28.6 0.0 6e-05 23.0 0.0 2.8 1 1 0 1 1 1 1 NACHT domain Abhydrolase_6 PF12697.7 KKK24833.1 - 2e-05 25.3 0.1 0.00026 21.6 0.0 2.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family AAA_22 PF13401.6 KKK24833.1 - 0.00046 20.5 0.0 0.0041 17.4 0.0 2.4 1 1 0 1 1 1 1 AAA domain DUF676 PF05057.14 KKK24833.1 - 0.0012 18.4 0.0 0.003 17.1 0.0 1.6 1 0 0 1 1 1 1 Putative serine esterase (DUF676) RNA_helicase PF00910.22 KKK24833.1 - 0.0051 17.2 0.0 0.012 16.0 0.0 1.6 1 0 0 1 1 1 1 RNA helicase Parvo_NS1 PF01057.17 KKK24833.1 - 0.03 13.4 0.0 0.1 11.7 0.0 1.7 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 PGAP1 PF07819.13 KKK24833.1 - 0.033 13.9 0.0 0.084 12.6 0.0 1.6 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_2 PF02230.16 KKK24833.1 - 0.07 12.9 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase AAA_16 PF13191.6 KKK24833.1 - 0.073 13.5 0.0 0.22 11.9 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain Abhydrolase_6 PF12697.7 KKK24834.1 - 4.3e-06 27.5 3.0 7.5e-06 26.7 3.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KKK24834.1 - 4.6e-05 23.2 0.1 8.2e-05 22.4 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KKK24834.1 - 0.0041 16.0 0.0 0.0054 15.6 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Glyco_hydro_130 PF04041.13 KKK24835.1 - 5.9e-36 124.0 0.0 7.5e-36 123.7 0.0 1.1 1 0 0 1 1 1 1 beta-1,4-mannooligosaccharide phosphorylase Glyco_hydro_43 PF04616.14 KKK24835.1 - 4.9e-09 35.9 1.7 0.0003 20.2 0.0 3.8 4 1 0 4 4 4 3 Glycosyl hydrolases family 43 Glyco_hydro_32N PF00251.20 KKK24835.1 - 1.3e-05 25.0 4.3 1.9e-05 24.4 0.0 2.4 3 0 0 3 3 3 1 Glycosyl hydrolases family 32 N-terminal domain AAA_16 PF13191.6 KKK24836.1 - 3e-07 31.0 0.1 1.4e-06 28.8 0.1 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KKK24836.1 - 0.0014 19.0 0.0 0.0042 17.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 KKK24836.1 - 0.015 15.8 0.0 0.042 14.3 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.13 KKK24836.1 - 0.015 14.5 0.0 0.027 13.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) ATPase_2 PF01637.18 KKK24836.1 - 0.082 12.8 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_7 PF12775.7 KKK24836.1 - 0.17 11.4 0.0 0.34 10.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region CPL PF08144.11 KKK24839.1 - 5.5e-31 107.8 0.1 1.7e-28 99.7 0.0 3.5 3 0 0 3 3 3 1 CPL (NUC119) domain PUF PF00806.19 KKK24839.1 - 0.11 12.2 0.0 7.5 6.5 0.0 3.1 3 0 0 3 3 3 0 Pumilio-family RNA binding repeat BSP_II PF05432.11 KKK24839.1 - 0.34 10.6 21.1 0.54 9.9 21.1 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) LAP1C PF05609.12 KKK24839.1 - 0.39 9.8 15.6 0.6 9.1 15.6 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) CDC27 PF09507.10 KKK24839.1 - 3.5 6.9 26.6 7 5.9 26.6 1.4 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 CDC45 PF02724.14 KKK24839.1 - 3.5 5.8 17.9 5.3 5.2 17.9 1.3 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 KKK24839.1 - 6.1 4.9 30.0 0.89 7.7 25.6 1.8 2 0 0 2 2 2 0 Nop14-like family Glyco_hydro_72 PF03198.14 KKK24840.1 - 5.8e-130 433.1 10.9 6.6e-130 433.0 10.9 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Glyco_hydro_2_C PF02836.17 KKK24840.1 - 0.022 13.9 0.5 0.056 12.5 0.5 1.9 1 1 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain DUF2406 PF10295.9 KKK24841.1 - 2.3e-20 73.0 0.2 2.7e-20 72.8 0.2 1.1 1 0 0 1 1 1 1 Uncharacterised protein (DUF2406) Sulfate_transp PF00916.20 KKK24842.1 - 2.1e-28 99.2 4.0 3.5e-28 98.5 4.0 1.3 1 0 0 1 1 1 1 Sulfate permease family cNMP_binding PF00027.29 KKK24842.1 - 5.7e-16 58.4 0.0 9.8e-16 57.6 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.21 KKK24842.1 - 1.7e-09 37.3 0.1 3.3e-09 36.4 0.1 1.4 1 0 0 1 1 1 1 STAS domain Sulfate_transp PF00916.20 KKK24843.1 - 3.1e-26 92.0 17.2 4.1e-26 91.6 17.2 1.1 1 0 0 1 1 1 1 Sulfate permease family Sld5 PF05916.11 KKK24844.1 - 1.7e-13 51.0 0.0 2.6e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 GINS complex protein HMG_box PF00505.19 KKK24845.1 - 2.5e-11 43.8 1.6 2.5e-11 43.8 1.6 1.7 2 0 0 2 2 2 1 HMG (high mobility group) box MATalpha_HMGbox PF04769.12 KKK24845.1 - 0.0034 16.7 0.1 0.0056 16.0 0.1 1.2 1 0 0 1 1 1 1 Mating-type protein MAT alpha 1 HMG-box HMG_box_2 PF09011.10 KKK24845.1 - 0.0051 17.4 0.9 0.014 16.0 0.9 1.7 1 0 0 1 1 1 1 HMG-box domain T5orf172 PF10544.9 KKK24845.1 - 0.1 13.2 0.4 0.24 11.9 0.4 1.6 1 0 0 1 1 1 0 T5orf172 domain PUF PF00806.19 KKK24846.1 - 8e-60 195.3 4.7 3.3e-08 32.8 0.0 8.5 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat ORC5_C PF14630.6 KKK24847.1 - 5e-67 226.4 0.0 3.9e-38 131.6 0.0 2.2 2 0 0 2 2 2 2 Origin recognition complex (ORC) subunit 5 C-terminus AAA_16 PF13191.6 KKK24847.1 - 6e-14 52.8 0.0 1.4e-13 51.6 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain Kelch_2 PF07646.15 KKK24848.1 - 0.11 12.5 0.0 0.34 11.0 0.0 1.8 1 0 0 1 1 1 0 Kelch motif WD40 PF00400.32 KKK24848.1 - 0.68 10.9 3.2 82 4.3 0.0 4.3 5 0 0 5 5 5 0 WD domain, G-beta repeat E1-E2_ATPase PF00122.20 KKK24849.1 - 2.8e-45 154.1 5.6 2.8e-45 154.1 5.6 3.0 4 0 0 4 4 4 1 E1-E2 ATPase Hydrolase PF00702.26 KKK24849.1 - 4.3e-16 59.9 0.2 1.8e-15 57.8 0.2 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KKK24849.1 - 2.6e-10 39.8 0.0 5.9e-10 38.7 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KKK24849.1 - 0.0028 17.4 0.7 0.0049 16.6 0.1 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase O-antigen_lig PF13425.6 KKK24849.1 - 0.11 11.2 5.6 0.32 9.8 5.6 1.7 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Cation_ATPase PF13246.6 KKK24849.1 - 0.2 11.8 0.0 0.42 10.7 0.0 1.5 1 0 0 1 1 1 0 Cation transport ATPase (P-type) RabGAP-TBC PF00566.18 KKK24853.1 - 3.6e-33 115.0 1.7 3.6e-33 115.0 1.7 1.5 2 0 0 2 2 2 1 Rab-GTPase-TBC domain SWI-SNF_Ssr4 PF08549.10 KKK24853.1 - 0.0092 14.7 2.9 0.017 13.8 2.9 1.3 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1750) Serine_rich PF08824.10 KKK24853.1 - 0.027 14.5 0.7 0.073 13.1 0.7 1.7 1 0 0 1 1 1 0 Serine rich protein interaction domain Gp-FAR-1 PF05823.12 KKK24853.1 - 0.062 13.7 0.7 0.12 12.8 0.7 1.4 1 0 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Ribosomal_S5 PF00333.20 KKK24853.1 - 0.13 12.3 0.2 0.28 11.2 0.2 1.6 1 0 0 1 1 1 0 Ribosomal protein S5, N-terminal domain Pkinase PF00069.25 KKK24854.1 - 2.7e-57 194.1 0.0 3.9e-57 193.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK24854.1 - 3.4e-20 72.4 0.0 5.2e-20 71.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KKK24854.1 - 2e-05 24.1 0.0 4.5e-05 22.9 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 KKK24854.1 - 8e-05 22.1 0.1 0.00013 21.4 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KKK24854.1 - 8.6e-05 22.6 0.1 0.014 15.3 0.1 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KKK24854.1 - 0.00039 19.5 0.0 0.00061 18.8 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 KKK24854.1 - 0.00054 18.9 0.0 0.00084 18.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 KKK24854.1 - 0.0014 18.2 0.0 0.0037 16.9 0.0 1.6 1 0 0 1 1 1 1 RIO1 family LRR_6 PF13516.6 KKK24855.1 - 5.2e-11 41.7 6.1 0.59 10.3 0.0 7.1 9 0 0 9 9 9 4 Leucine Rich repeat F-box-like PF12937.7 KKK24855.1 - 3.4e-10 39.7 0.0 1.1e-09 38.0 0.0 1.9 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KKK24855.1 - 2.5e-09 36.8 0.6 1.4e-08 34.4 0.1 2.6 3 0 0 3 3 3 1 F-box domain LRR_4 PF12799.7 KKK24855.1 - 4.8e-06 26.8 5.1 0.0022 18.4 0.0 5.2 4 2 2 6 6 6 1 Leucine Rich repeats (2 copies) Sugar_tr PF00083.24 KKK24855.1 - 0.0061 15.5 0.1 0.0091 14.9 0.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter LRR_1 PF00560.33 KKK24855.1 - 0.076 13.6 9.5 47 5.1 0.0 6.0 7 1 0 7 7 7 0 Leucine Rich Repeat Yippee-Mis18 PF03226.14 KKK24856.1 - 1e-18 67.5 1.8 1.1e-18 67.3 1.8 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RIG-I_C-RD PF11648.8 KKK24856.1 - 0.0032 17.7 1.1 0.0045 17.2 1.1 1.3 1 0 0 1 1 1 1 C-terminal domain of RIG-I DUF2039 PF10217.9 KKK24856.1 - 0.0075 16.6 2.4 0.017 15.4 0.4 2.1 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2039) HNH_5 PF14279.6 KKK24856.1 - 0.038 13.8 0.3 1.4 8.9 0.0 2.3 2 0 0 2 2 2 0 HNH endonuclease Evr1_Alr PF04777.13 KKK24856.1 - 0.075 13.5 1.2 2.1 8.9 0.1 2.1 1 1 1 2 2 2 0 Erv1 / Alr family zf-RRPl_C4 PF17026.5 KKK24856.1 - 0.088 12.9 4.5 0.26 11.4 1.3 2.3 1 1 1 2 2 2 0 Putative ribonucleoprotein zinc-finger pf C4 type Endonuclease_7 PF02945.15 KKK24856.1 - 0.56 10.2 4.2 0.24 11.3 1.0 2.2 1 1 1 2 2 2 0 Recombination endonuclease VII PTS_2-RNA PF01885.16 KKK24857.1 - 5.3e-66 222.1 0.0 8.2e-66 221.5 0.0 1.3 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family WD40 PF00400.32 KKK24857.1 - 0.0033 18.2 0.1 8.1 7.5 0.1 4.6 3 0 0 3 3 3 1 WD domain, G-beta repeat zinc_ribbon_16 PF17034.5 KKK24857.1 - 0.071 13.3 0.5 0.16 12.2 0.5 1.6 1 0 0 1 1 1 0 Zinc-ribbon like family Hexokinase_1 PF00349.21 KKK24857.1 - 0.14 12.0 0.0 0.31 10.9 0.0 1.5 1 0 0 1 1 1 0 Hexokinase Na_H_antiport_3 PF07399.11 KKK24857.1 - 0.24 10.2 0.0 0.36 9.7 0.0 1.1 1 0 0 1 1 1 0 Putative Na+/H+ antiporter Efg1 PF10153.9 KKK24858.1 - 1.1e-32 112.8 10.9 1.1e-32 112.8 10.9 1.8 2 0 0 2 2 2 1 rRNA-processing protein Efg1 DUF2489 PF10675.9 KKK24858.1 - 0.049 13.6 0.5 0.049 13.6 0.5 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2489) Pox_A_type_inc PF04508.12 KKK24858.1 - 0.12 12.3 1.2 0.47 10.4 1.2 2.1 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat TMF_TATA_bd PF12325.8 KKK24858.1 - 0.18 12.1 6.1 4.4 7.6 1.2 2.9 3 0 0 3 3 3 0 TATA element modulatory factor 1 TATA binding ER_lumen_recept PF00810.18 KKK24859.1 - 5.6e-43 147.3 4.6 9.1e-43 146.6 4.6 1.3 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.14 KKK24859.1 - 0.0079 15.9 0.0 0.0079 15.9 0.0 3.5 4 0 0 4 4 4 2 PQ loop repeat Phage_holin_1 PF04531.13 KKK24859.1 - 0.75 10.4 2.8 2.2 8.9 0.9 2.4 2 0 0 2 2 2 0 Bacteriophage holin eRF1_1 PF03463.15 KKK24861.1 - 2.9e-48 163.1 0.0 4.4e-48 162.5 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_3 PF03465.15 KKK24861.1 - 8.9e-19 68.0 0.0 1.6e-18 67.2 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_2 PF03464.15 KKK24861.1 - 8.4e-18 65.0 0.0 1.3e-17 64.4 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 2 LptE PF04390.12 KKK24861.1 - 0.032 14.9 0.2 1.1 10.0 0.0 2.6 2 1 0 2 2 2 0 Lipopolysaccharide-assembly TerB_C PF15615.6 KKK24862.1 - 4.8 7.5 10.1 0.54 10.5 4.8 2.0 2 0 0 2 2 2 0 TerB-C domain DUF4551 PF15087.6 KKK24862.1 - 5.4 5.7 7.3 6.5 5.5 7.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Abhydrolase_1 PF00561.20 KKK24863.1 - 1.1e-21 77.7 0.1 5.2e-19 68.9 0.1 2.0 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KKK24863.1 - 1.4e-18 67.1 0.1 2.3e-18 66.3 0.1 1.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KKK24863.1 - 2.4e-16 61.0 0.0 3.4e-16 60.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.14 KKK24863.1 - 1.4e-08 33.8 0.0 2.3e-08 33.1 0.0 1.3 1 1 0 1 1 1 1 Ndr family BAAT_C PF08840.11 KKK24863.1 - 5.4e-06 26.5 0.1 1.3e-05 25.2 0.1 1.6 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S9 PF00326.21 KKK24863.1 - 8.1e-06 25.5 0.0 0.023 14.2 0.0 2.2 1 1 1 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 KKK24863.1 - 6.2e-05 22.9 0.1 0.12 12.1 0.0 3.0 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase DLH PF01738.18 KKK24863.1 - 0.00019 21.0 0.1 0.47 10.0 0.1 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family Ser_hydrolase PF06821.13 KKK24863.1 - 0.0007 19.5 0.2 0.011 15.6 0.2 2.1 1 1 0 1 1 1 1 Serine hydrolase Abhydrolase_5 PF12695.7 KKK24863.1 - 0.0025 17.6 0.1 0.0073 16.1 0.1 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family PGAP1 PF07819.13 KKK24863.1 - 0.0035 17.1 1.2 0.0095 15.7 0.3 2.0 2 0 0 2 2 2 1 PGAP1-like protein Esterase PF00756.20 KKK24863.1 - 0.0038 16.9 0.5 0.016 14.8 0.5 1.9 1 1 0 1 1 1 1 Putative esterase Thioesterase PF00975.20 KKK24863.1 - 0.0075 16.4 0.0 0.0083 16.3 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain DUF676 PF05057.14 KKK24863.1 - 0.009 15.5 0.1 0.03 13.8 0.0 1.8 1 1 1 2 2 2 1 Putative serine esterase (DUF676) DUF915 PF06028.11 KKK24863.1 - 0.022 14.1 0.0 0.12 11.7 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Lipase PF00151.19 KKK24863.1 - 0.023 14.0 0.1 0.045 13.1 0.1 1.4 2 0 0 2 2 2 0 Lipase UPF0227 PF05728.12 KKK24863.1 - 0.027 14.4 0.3 0.051 13.5 0.2 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0227) PAF-AH_p_II PF03403.13 KKK24863.1 - 0.047 12.2 0.2 1.1 7.6 0.0 2.3 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II Lipase_3 PF01764.25 KKK24863.1 - 0.15 11.9 0.5 0.36 10.7 0.4 1.6 1 1 0 1 1 1 0 Lipase (class 3) Dioxygenase_C PF00775.21 KKK24864.1 - 1.6e-49 167.8 0.0 2.1e-49 167.4 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 KKK24864.1 - 4.5e-28 96.9 0.2 7.3e-28 96.2 0.2 1.3 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.6 KKK24864.1 - 1.4e-05 25.3 0.0 2.8e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain CarbopepD_reg_2 PF13715.6 KKK24864.1 - 0.017 15.1 0.0 2.1 8.4 0.0 3.1 3 0 0 3 3 3 0 CarboxypepD_reg-like domain Lipase_C PF18067.1 KKK24864.1 - 0.056 14.0 0.0 0.11 13.1 0.0 1.5 1 0 0 1 1 1 0 Lipase C-terminal domain Xpo1 PF08389.12 KKK24865.1 - 1.9e-23 83.2 0.0 1.4e-22 80.3 0.0 2.6 2 0 0 2 2 2 1 Exportin 1-like protein IBN_N PF03810.19 KKK24865.1 - 0.00024 21.0 0.2 0.00081 19.3 0.0 2.1 2 0 0 2 2 2 1 Importin-beta N-terminal domain Urb2 PF10441.9 KKK24865.1 - 0.011 15.6 0.0 0.2 11.6 0.0 2.8 2 1 0 3 3 3 0 Urb2/Npa2 family HEAT_EZ PF13513.6 KKK24865.1 - 0.023 15.2 0.4 1.2 9.7 0.0 4.0 4 0 0 4 4 4 0 HEAT-like repeat Importin_rep_3 PF18806.1 KKK24865.1 - 0.053 13.6 0.0 0.28 11.2 0.0 2.2 2 0 0 2 2 2 0 Importin 13 repeat Adaptin_N PF01602.20 KKK24865.1 - 0.065 11.8 0.2 0.22 10.0 0.1 1.8 2 0 0 2 2 2 0 Adaptin N terminal region HEAT_2 PF13646.6 KKK24865.1 - 0.13 12.7 0.0 0.6 10.5 0.0 2.2 1 0 0 1 1 1 0 HEAT repeats Nucleoporin_N PF08801.11 KKK24866.1 - 4.6e-93 312.3 0.1 5.6e-93 312.0 0.1 1.1 1 0 0 1 1 1 1 Nup133 N terminal like Rot1 PF10681.9 KKK24867.1 - 5.5e-93 310.3 0.0 6.3e-93 310.1 0.0 1.0 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal YqeY PF09424.10 KKK24868.1 - 2.2e-19 70.0 1.7 2.6e-19 69.7 1.7 1.1 1 0 0 1 1 1 1 Yqey-like protein Cellulase PF00150.18 KKK24868.1 - 0.019 14.4 0.0 0.042 13.3 0.0 1.5 2 0 0 2 2 2 0 Cellulase (glycosyl hydrolase family 5) DUF659 PF04937.15 KKK24868.1 - 0.035 14.0 0.0 0.049 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF 659) ParcG PF10274.9 KKK24868.1 - 0.038 14.1 0.0 0.05 13.7 0.0 1.2 1 0 0 1 1 1 0 Parkin co-regulated protein Arm_vescicular PF18770.1 KKK24868.1 - 0.16 12.0 0.1 0.97 9.4 0.0 2.2 2 0 0 2 2 2 0 Armadillo tether-repeat of vescicular transport factor LSM PF01423.22 KKK24869.1 - 4.5e-13 48.7 0.0 5.2e-13 48.5 0.0 1.1 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 KKK24869.1 - 0.0014 18.3 0.1 0.002 17.7 0.1 1.3 1 0 0 1 1 1 1 Hfq protein 5-FTHF_cyc-lig PF01812.20 KKK24870.1 - 3.1e-23 82.6 0.0 5.5e-23 81.8 0.0 1.4 1 1 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family CCDC53 PF10152.9 KKK24874.1 - 3 8.2 5.6 0.3 11.5 0.3 2.0 3 0 0 3 3 3 0 Subunit CCDC53 of WASH complex Mito_fiss_reg PF05308.11 KKK24874.1 - 6.2 6.8 7.9 21 5.1 7.9 1.9 1 0 0 1 1 1 0 Mitochondrial fission regulator WD40 PF00400.32 KKK24875.1 - 1.7e-38 129.9 20.4 1.5e-10 41.4 0.2 8.1 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKK24875.1 - 5.7e-12 45.8 0.8 0.015 15.6 0.0 4.4 2 1 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KKK24875.1 - 1.6e-08 33.7 1.7 0.066 11.9 0.1 4.5 5 0 0 5 5 5 4 Nucleoporin Nup120/160 PALB2_WD40 PF16756.5 KKK24875.1 - 1.9e-05 23.8 2.4 4.8e-05 22.4 0.1 2.6 4 0 0 4 4 4 1 Partner and localizer of BRCA2 WD40 domain Ge1_WD40 PF16529.5 KKK24875.1 - 0.00023 20.2 0.1 0.59 9.0 0.0 3.9 3 2 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KKK24875.1 - 0.022 14.6 0.5 0.28 11.0 0.0 2.6 2 1 1 3 3 3 0 Eukaryotic translation initiation factor eIF2A Hira PF07569.11 KKK24875.1 - 0.023 14.4 1.5 0.69 9.6 0.1 3.3 2 1 2 4 4 4 0 TUP1-like enhancer of split Frtz PF11768.8 KKK24875.1 - 0.027 12.8 0.0 0.099 10.9 0.0 1.7 1 1 1 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz DUF1513 PF07433.11 KKK24875.1 - 0.098 11.7 0.9 1.7 7.7 0.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1513) Tctex-1 PF03645.13 KKK24876.1 - 2.2e-35 121.0 0.0 2.5e-35 120.8 0.0 1.1 1 0 0 1 1 1 1 Tctex-1 family DUF202 PF02656.15 KKK24877.1 - 2.4e-13 50.3 5.1 2.4e-13 50.3 5.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF5337 PF17272.2 KKK24877.1 - 1.1 9.1 11.1 0.075 12.9 5.5 2.1 2 1 0 2 2 2 0 Family of unknown function (DUF5337) DUF4131 PF13567.6 KKK24877.1 - 2.9 7.5 5.9 3.5 7.2 4.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) ketoacyl-synt PF00109.26 KKK24878.1 - 8.1e-60 202.5 0.4 9.1e-60 202.4 0.4 1.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Thiolase_N PF00108.23 KKK24878.1 - 0.00012 21.6 0.1 0.00018 20.9 0.1 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Trypan_PARP PF05887.11 KKK24879.1 - 0.95 9.4 8.2 0.18 11.7 2.4 2.2 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Nop PF01798.18 KKK24880.1 - 4.2e-62 209.6 0.1 5.9e-62 209.1 0.1 1.2 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin Prp31_C PF09785.9 KKK24880.1 - 7e-48 162.5 0.9 2.3e-47 160.8 0.9 2.0 1 1 0 1 1 1 1 Prp31 C terminal domain TPR_14 PF13428.6 KKK24881.1 - 1.1e-20 72.6 25.2 0.00049 20.7 0.0 11.6 6 2 8 14 14 14 7 Tetratricopeptide repeat HAT PF02184.16 KKK24881.1 - 4.4e-20 71.3 81.2 1.7e-13 50.2 6.0 13.3 14 0 0 14 14 14 6 HAT (Half-A-TPR) repeat Suf PF05843.14 KKK24881.1 - 1.8e-17 64.3 23.4 9e-06 25.9 0.8 6.3 3 2 3 6 6 6 4 Suppressor of forked protein (Suf) TPR_19 PF14559.6 KKK24881.1 - 6.1e-16 58.7 0.0 0.00019 21.9 0.0 6.7 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_17 PF13431.6 KKK24881.1 - 1.1e-11 44.3 0.7 0.053 13.9 0.0 6.5 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.17 KKK24881.1 - 3.3e-08 33.0 8.9 0.12 12.5 0.0 8.2 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_8 PF13181.6 KKK24881.1 - 1.2e-05 25.1 5.4 42 4.7 0.0 7.7 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_6 PF13174.6 KKK24881.1 - 0.0027 18.2 15.2 3.6 8.4 0.0 7.4 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_16 PF13432.6 KKK24881.1 - 0.012 16.3 12.2 3.8 8.2 0.0 7.7 8 1 1 9 9 9 0 Tetratricopeptide repeat NifW PF03206.14 KKK24881.1 - 0.16 12.5 1.3 2.1 8.9 0.2 3.4 3 0 0 3 3 3 0 Nitrogen fixation protein NifW NRDE-2 PF08424.10 KKK24881.1 - 0.24 10.5 28.1 0.39 9.8 1.1 6.2 3 2 1 5 5 5 0 NRDE-2, necessary for RNA interference TPR_1 PF00515.28 KKK24881.1 - 0.32 10.9 3.4 6.4 6.8 0.0 4.4 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 KKK24881.1 - 0.74 10.1 18.6 15 6.0 0.0 7.6 9 0 0 9 9 8 0 Tetratricopeptide repeat U3_assoc_6 PF08640.11 KKK24881.1 - 7 6.8 30.4 0.61 10.2 2.4 6.7 7 1 1 8 8 8 0 U3 small nucleolar RNA-associated protein 6 DUF5321 PF17254.2 KKK24921.1 - 2.8e-53 179.6 9.3 3.3e-53 179.4 8.5 1.5 1 1 0 1 1 1 1 Family of unknown function (DUF5321) BRF1 PF07741.13 KKK24921.1 - 0.00067 20.0 12.1 0.0012 19.1 12.1 1.4 1 0 0 1 1 1 1 Brf1-like TBP-binding domain RskA PF10099.9 KKK24921.1 - 0.0045 17.3 7.8 0.12 12.6 3.6 2.3 2 0 0 2 2 2 2 Anti-sigma-K factor rskA DUF755 PF05501.11 KKK24921.1 - 0.0078 16.5 3.9 0.0078 16.5 3.9 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF755) DUF3391 PF11871.8 KKK24921.1 - 0.026 15.1 10.6 0.045 14.3 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) TAF4 PF05236.14 KKK24921.1 - 0.33 10.7 15.9 0.44 10.2 15.9 1.2 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family Vfa1 PF08432.10 KKK24921.1 - 2.9 8.2 14.4 4.1 7.7 14.4 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Mito_carr PF00153.27 KKK24922.1 - 1.8e-24 85.5 0.1 8.7e-24 83.3 0.0 1.8 2 0 0 2 2 2 1 Mitochondrial carrier protein GNAT_like PF18407.1 KKK24922.1 - 0.11 12.9 0.0 0.21 12.0 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyltransferase like domain Peptidase_M22 PF00814.25 KKK24923.1 - 3.9e-46 157.9 0.0 1.6e-44 152.7 0.0 2.5 1 1 0 1 1 1 1 Glycoprotease family FGGY_C PF02782.16 KKK24923.1 - 0.041 13.6 0.0 0.077 12.7 0.0 1.4 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain YycC PF14174.6 KKK24923.1 - 0.1 12.4 0.1 0.28 11.0 0.1 1.7 1 0 0 1 1 1 0 YycC-like protein Peptidase_C50 PF03568.17 KKK24924.1 - 1.8e-155 518.0 0.0 4.4e-155 516.7 0.0 1.7 2 0 0 2 2 2 1 Peptidase family C50 Esterase PF00756.20 KKK24924.1 - 4.2e-53 180.6 0.0 8.9e-53 179.5 0.0 1.5 1 0 0 1 1 1 1 Putative esterase CHAT PF12770.7 KKK24924.1 - 2.3e-06 27.3 0.3 9.5e-05 21.9 0.0 3.2 3 0 0 3 3 3 1 CHAT domain Esterase_phd PF10503.9 KKK24924.1 - 0.00075 19.0 0.0 0.0035 16.9 0.0 2.1 1 1 0 1 1 1 1 Esterase PHB depolymerase TPR_12 PF13424.6 KKK24924.1 - 0.0073 16.6 19.9 3 8.2 0.0 6.1 5 1 0 6 6 6 1 Tetratricopeptide repeat Peptidase_S9 PF00326.21 KKK24924.1 - 0.0076 15.7 0.0 0.015 14.8 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family TPR_2 PF07719.17 KKK24924.1 - 0.013 15.5 8.9 2.3 8.5 0.1 5.4 5 0 0 5 5 5 0 Tetratricopeptide repeat Hydrolase_4 PF12146.8 KKK24924.1 - 0.03 13.6 0.0 0.07 12.4 0.0 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Lipase_3 PF01764.25 KKK24924.1 - 0.1 12.5 0.0 0.29 11.0 0.0 1.7 1 0 0 1 1 1 0 Lipase (class 3) DUF1980 PF09323.10 KKK24924.1 - 0.17 11.8 0.2 0.34 10.8 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) TPR_1 PF00515.28 KKK24924.1 - 0.81 9.6 2.6 23 5.0 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat Zn_clus PF00172.18 KKK24926.1 - 8e-08 32.3 9.3 8e-08 32.3 9.3 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KKK24926.1 - 0.0016 17.3 5.9 0.036 12.9 1.1 2.7 2 1 0 2 2 2 2 Fungal specific transcription factor domain Opy2 PF09463.10 KKK24926.1 - 0.54 10.6 5.9 1.7 9.0 5.9 1.9 1 0 0 1 1 1 0 Opy2 protein Cu-oxidase_3 PF07732.15 KKK24927.1 - 1.3e-35 122.0 0.1 1.2e-34 118.9 0.0 2.6 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 KKK24927.1 - 1.3e-33 115.6 0.4 1.6e-26 92.7 0.0 3.5 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.22 KKK24927.1 - 9.1e-16 58.4 0.0 1.7e-14 54.3 0.0 2.9 3 1 0 3 3 3 1 Multicopper oxidase Choline_kinase PF01633.20 KKK24927.1 - 0.18 11.4 0.0 0.29 10.7 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase VWA_2 PF13519.6 KKK24929.1 - 0.0039 17.8 0.0 0.0079 16.8 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 KKK24929.1 - 0.015 15.5 0.0 3.1 8.0 0.0 2.1 2 0 0 2 2 2 0 von Willebrand factor type A domain Fungal_trans_2 PF11951.8 KKK24930.1 - 1e-60 205.6 0.9 1.5e-60 205.1 0.9 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK24930.1 - 2.3e-08 34.0 11.2 4e-08 33.3 11.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Hormone_recep PF00104.30 KKK24930.1 - 0.015 14.8 0.0 0.029 13.9 0.0 1.4 1 0 0 1 1 1 0 Ligand-binding domain of nuclear hormone receptor Guanylate_kin PF00625.21 KKK24931.1 - 1e-19 70.9 0.1 1.2e-19 70.7 0.1 1.0 1 0 0 1 1 1 1 Guanylate kinase Asp1 PF16993.5 KKK24931.1 - 0.16 11.2 0.0 0.19 10.9 0.0 1.0 1 0 0 1 1 1 0 Accessory Sec system protein Asp1 T3SS_needle_E PF08988.10 KKK24931.1 - 0.29 11.3 1.7 0.63 10.2 1.6 1.7 1 1 0 1 1 1 0 Type III secretion system, cytoplasmic E component of needle Septin PF00735.18 KKK24932.1 - 6.8e-113 376.6 0.2 8e-113 376.4 0.2 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 KKK24932.1 - 1.6e-07 31.4 0.0 3.9e-07 30.1 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 KKK24932.1 - 1.1e-05 24.8 0.0 2e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 AIG1 family GTP_EFTU PF00009.27 KKK24932.1 - 9.7e-05 22.0 0.6 0.027 14.0 0.1 2.5 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KKK24932.1 - 0.0001 22.2 0.4 0.00092 19.2 0.1 2.2 2 0 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 KKK24932.1 - 0.0011 19.0 0.3 1.5 8.9 0.0 2.5 1 1 1 2 2 2 2 Dynamin family AAA_16 PF13191.6 KKK24932.1 - 0.0015 19.0 0.1 0.006 17.0 0.1 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_7 PF12775.7 KKK24932.1 - 0.0018 17.8 0.1 0.0095 15.5 0.0 2.2 2 0 0 2 2 2 1 P-loop containing dynein motor region NB-ARC PF00931.22 KKK24932.1 - 0.0055 15.9 0.1 0.0095 15.1 0.1 1.3 1 0 0 1 1 1 1 NB-ARC domain ABC_tran PF00005.27 KKK24932.1 - 0.019 15.5 0.2 0.03 14.8 0.1 1.6 1 1 0 1 1 1 0 ABC transporter AAA_22 PF13401.6 KKK24932.1 - 0.022 15.1 0.0 0.041 14.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain Gtr1_RagA PF04670.12 KKK24932.1 - 0.035 13.5 0.1 0.47 9.8 0.0 2.1 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region FtsK_SpoIIIE PF01580.18 KKK24932.1 - 0.043 13.2 0.0 0.078 12.3 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family G-alpha PF00503.20 KKK24932.1 - 0.047 12.9 0.3 0.31 10.1 0.1 1.7 1 1 1 2 2 2 0 G-protein alpha subunit Roc PF08477.13 KKK24932.1 - 0.087 13.0 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase WD40 PF00400.32 KKK24933.1 - 1.4e-24 85.9 16.9 5.1e-08 33.5 0.9 6.7 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKK24933.1 - 1.6e-18 66.8 0.7 0.00066 19.9 0.8 4.6 1 1 3 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Ribosomal_L32p PF01783.23 KKK24933.1 - 2.1e-13 50.3 7.1 4.2e-13 49.3 7.1 1.4 1 0 0 1 1 1 1 Ribosomal L32p protein family Lactonase PF10282.9 KKK24933.1 - 3.1e-06 26.7 0.0 0.004 16.5 0.0 2.5 1 1 2 3 3 3 2 Lactonase, 7-bladed beta-propeller eIF2A PF08662.11 KKK24933.1 - 1.7e-05 24.8 0.0 0.016 15.1 0.0 2.4 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KKK24933.1 - 0.0003 19.6 0.1 0.0083 14.8 0.1 2.1 2 0 0 2 2 2 1 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 KKK24933.1 - 0.001 17.7 0.0 0.0026 16.4 0.0 1.6 1 1 0 1 1 1 1 Cytochrome D1 heme domain Ge1_WD40 PF16529.5 KKK24933.1 - 0.013 14.5 1.2 1.3 7.9 0.0 3.2 1 1 2 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 KKK24933.1 - 0.017 14.5 0.5 2 7.7 0.0 3.5 2 2 2 4 4 4 0 Neuroblastoma-amplified sequence, N terminal Stc1 PF12898.7 KKK24933.1 - 0.051 14.1 0.6 0.11 13.1 0.6 1.4 1 0 0 1 1 1 0 Stc1 domain WD40_like PF17005.5 KKK24933.1 - 0.083 12.2 0.0 4.9 6.4 0.0 2.5 1 1 2 3 3 3 0 WD40-like domain zf-ribbon_3 PF13248.6 KKK24933.1 - 0.12 11.9 2.8 0.28 10.7 2.8 1.7 1 0 0 1 1 1 0 zinc-ribbon domain Coatomer_WDAD PF04053.14 KKK24933.1 - 0.13 11.3 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 Coatomer WD associated region DUF2293 PF10056.9 KKK24935.1 - 1.5e-29 102.1 0.1 2.8e-29 101.2 0.1 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2293) HMA PF00403.26 KKK24936.1 - 4.1e-16 59.2 0.7 4.8e-16 59.0 0.7 1.1 1 0 0 1 1 1 1 Heavy-metal-associated domain Rrn6 PF10214.9 KKK24937.1 - 2.4e-217 724.4 8.4 2.7e-217 724.3 8.4 1.0 1 0 0 1 1 1 1 RNA polymerase I-specific transcription-initiation factor Spindle_Spc25 PF08234.12 KKK24938.1 - 6.3e-23 80.8 0.1 2.1e-22 79.1 0.1 2.0 1 0 0 1 1 1 1 Chromosome segregation protein Spc25 CT_C_D PF02682.16 KKK24938.1 - 0.11 12.2 1.6 0.22 11.2 1.6 1.4 1 0 0 1 1 1 0 Carboxyltransferase domain, subdomain C and D Hom_end_hint PF05203.16 KKK24938.1 - 0.15 12.0 0.6 0.18 11.7 0.6 1.1 1 0 0 1 1 1 0 Hom_end-associated Hint DUF4140 PF13600.6 KKK24938.1 - 6.1 7.3 8.9 7.4 7.1 7.6 1.9 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Tcp11 PF05794.13 KKK24939.1 - 4.5e-115 385.3 0.0 4.5e-115 385.3 0.0 2.8 3 0 0 3 3 3 2 T-complex protein 11 zinc_ribbon_6 PF14599.6 KKK24940.1 - 2.8e-24 84.9 0.4 2.8e-24 84.9 0.4 3.5 3 0 0 3 3 2 1 Zinc-ribbon zf-CHY PF05495.12 KKK24940.1 - 4.7e-19 68.7 21.5 4.7e-19 68.7 21.5 3.6 2 1 1 3 3 2 1 CHY zinc finger zf-RING_2 PF13639.6 KKK24940.1 - 6.4e-09 36.0 6.9 6.4e-09 36.0 6.9 5.2 2 1 4 6 6 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 KKK24940.1 - 4.5e-06 26.4 4.6 4.5e-06 26.4 4.6 4.9 4 2 0 4 4 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KKK24940.1 - 9.2e-06 25.4 7.1 9.2e-06 25.4 7.1 5.8 2 1 3 5 5 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KKK24940.1 - 9.4e-06 25.6 5.5 9.4e-06 25.6 5.5 3.6 3 0 0 3 3 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 KKK24940.1 - 0.0011 19.0 6.8 0.0011 19.0 6.8 4.8 5 1 1 6 6 3 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 KKK24940.1 - 0.0085 15.9 6.8 0.0085 15.9 6.8 5.2 4 2 1 5 5 4 1 Prokaryotic RING finger family 4 RNA_pol_3_Rpc31 PF11705.8 KKK24940.1 - 0.9 9.7 15.2 1.7 8.9 15.2 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Nop14 PF04147.12 KKK24940.1 - 0.97 7.6 16.4 1.4 7.1 16.4 1.1 1 0 0 1 1 1 0 Nop14-like family TFIIA PF03153.13 KKK24940.1 - 5.3 6.9 15.0 0.079 12.9 6.5 2.0 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Tim54 PF11711.8 KKK24940.1 - 7.7 5.2 6.1 15 4.3 6.1 1.4 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 WD40 PF00400.32 KKK24941.1 - 1.7e-20 72.9 6.9 5.4e-06 27.0 0.5 5.4 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKK24941.1 - 5.9e-10 39.3 0.4 0.11 12.8 0.0 3.6 2 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 KKK24941.1 - 0.13 11.3 0.1 0.19 10.7 0.1 1.1 1 0 0 1 1 1 0 Coatomer WD associated region Glyco_hydro_7 PF00840.20 KKK24942.1 - 1.3e-208 693.1 12.1 1.3e-208 693.1 12.1 1.6 2 0 0 2 2 2 1 Glycosyl hydrolase family 7 CBM_1 PF00734.18 KKK24942.1 - 1.2e-13 50.8 11.8 1.2e-13 50.8 11.8 3.4 4 0 0 4 4 4 1 Fungal cellulose binding domain Toxin_7 PF05980.12 KKK24942.1 - 2.5 8.4 8.9 0.26 11.6 3.9 2.0 2 0 0 2 2 2 0 Toxin 7 Cellulase PF00150.18 KKK24943.1 - 2.1e-55 188.1 0.2 3.7e-55 187.3 0.2 1.4 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.18 KKK24943.1 - 1e-13 51.0 11.2 1e-13 51.0 11.2 2.5 2 0 0 2 2 2 1 Fungal cellulose binding domain BAF1_ABF1 PF04684.13 KKK24943.1 - 0.036 13.1 5.1 0.04 13.0 5.1 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Fungal_trans PF04082.18 KKK24944.1 - 3.4e-22 78.8 1.4 6.2e-22 77.9 1.4 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 KKK24944.1 - 9e-10 38.5 12.7 6.4e-05 23.2 0.6 2.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KKK24944.1 - 7.8e-09 35.6 12.8 9.7e-08 32.1 4.8 3.2 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KKK24944.1 - 4.6e-07 30.1 7.5 0.0014 19.3 2.0 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-FPG_IleRS PF06827.14 KKK24944.1 - 0.064 13.1 2.1 0.65 9.9 2.1 2.4 1 1 0 1 1 1 0 Zinc finger found in FPG and IleRS zf-C2H2_6 PF13912.6 KKK24944.1 - 0.15 12.1 6.5 0.5 10.4 1.9 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KKK24944.1 - 0.26 11.6 1.9 0.63 10.4 0.3 2.2 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.6 KKK24944.1 - 0.44 10.5 5.5 0.32 10.9 1.0 2.6 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf_UBZ PF18439.1 KKK24944.1 - 0.5 10.0 2.5 7.9 6.2 0.3 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger Glyco_hydro_28 PF00295.17 KKK24945.1 - 2.4e-120 401.5 20.1 2.7e-120 401.3 20.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 DUF2180 PF09947.9 KKK24945.1 - 0.065 13.2 0.2 0.13 12.3 0.2 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2180) Ammonium_transp PF00909.21 KKK24946.1 - 1.3e-68 231.6 17.7 1.7e-68 231.1 17.7 1.1 1 0 0 1 1 1 1 Ammonium Transporter Family Formyl_trans_N PF00551.19 KKK24947.1 - 2.2e-39 135.0 0.0 2.9e-39 134.7 0.0 1.1 1 0 0 1 1 1 1 Formyl transferase ACT PF01842.25 KKK24947.1 - 8.6e-08 31.8 0.0 2.3e-07 30.4 0.0 1.7 1 0 0 1 1 1 1 ACT domain ACT_6 PF13740.6 KKK24947.1 - 6.1e-06 26.1 0.0 2.6e-05 24.1 0.0 2.0 2 0 0 2 2 2 1 ACT domain MFS_1 PF07690.16 KKK24948.1 - 4.2e-42 144.3 30.1 4.2e-42 144.3 30.1 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KKK24948.1 - 1.1e-07 30.7 7.6 1.5e-07 30.3 7.6 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KKK24948.1 - 1.8e-07 30.4 11.9 1.8e-07 30.4 11.9 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter LapA_dom PF06305.11 KKK24948.1 - 9.9 6.1 10.1 25 4.8 0.7 4.6 5 0 0 5 5 5 0 Lipopolysaccharide assembly protein A domain APH PF01636.23 KKK24949.1 - 1.2e-09 38.5 0.0 8.4e-09 35.7 0.0 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KKK24949.1 - 0.02 14.5 0.0 0.031 13.9 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase RIO1 PF01163.22 KKK24949.1 - 0.24 11.0 0.0 1.3 8.6 0.0 2.0 2 0 0 2 2 2 0 RIO1 family TauD PF02668.16 KKK24950.1 - 4.1e-51 174.4 0.4 4.6e-51 174.2 0.4 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Sua5_yciO_yrdC PF01300.18 KKK24951.1 - 1.7e-12 47.2 0.0 5.3e-12 45.6 0.0 1.9 1 1 0 1 1 1 1 Telomere recombination GDPD PF03009.17 KKK24952.1 - 1.4e-10 41.4 0.0 3.7e-10 40.0 0.0 1.8 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Aminotran_1_2 PF00155.21 KKK24976.1 - 1.5e-05 24.3 0.0 2e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II RAP1 PF07218.11 KKK24976.1 - 0.2 9.9 4.1 0.18 10.0 4.1 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DNA_pol_D_N PF18018.1 KKK24977.1 - 4.5e-40 136.8 0.0 6.5e-40 136.2 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain DNA_pol_E_B PF04042.16 KKK24977.1 - 4.5e-35 120.9 0.0 6.9e-34 117.1 0.0 2.2 1 1 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Methyltransf_16 PF10294.9 KKK24980.1 - 8.5e-58 194.9 0.0 1.5e-57 194.1 0.0 1.4 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_31 PF13847.6 KKK24980.1 - 0.0013 18.5 0.0 0.002 17.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKK24980.1 - 0.018 15.8 0.0 0.038 14.7 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 KKK24980.1 - 0.14 12.9 0.0 0.27 12.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain adh_short PF00106.25 KKK24982.1 - 4.5e-28 98.0 0.1 3.2e-22 79.0 0.0 2.1 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KKK24982.1 - 3.7e-17 62.7 0.0 2.1e-13 50.4 0.0 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KKK24982.1 - 0.00026 20.9 0.5 0.25 11.2 0.4 2.1 1 1 1 2 2 2 2 KR domain NMO PF03060.15 KKK24984.1 - 3e-54 184.7 0.4 4.3e-54 184.1 0.4 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 KKK24984.1 - 2.3e-09 36.7 1.2 2.3e-09 36.7 1.2 1.5 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 KKK24984.1 - 0.0003 20.0 3.1 0.00054 19.1 3.1 1.4 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 KKK24984.1 - 0.19 10.8 0.8 0.33 10.0 0.8 1.3 1 0 0 1 1 1 0 Conserved region in glutamate synthase Taxilin PF09728.9 KKK24985.1 - 4e-93 312.0 52.6 4e-93 312.0 52.6 1.6 2 0 0 2 2 2 1 Myosin-like coiled-coil protein GOLGA2L5 PF15070.6 KKK24985.1 - 0.77 8.3 45.3 0.26 9.9 34.3 2.1 1 1 1 2 2 2 0 Putative golgin subfamily A member 2-like protein 5 DUF3675 PF12428.8 KKK24985.1 - 1 9.9 2.4 13 6.4 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3675) DUF4201 PF13870.6 KKK24985.1 - 7.8 6.2 55.7 0.017 14.9 14.6 4.4 1 1 3 5 5 5 0 Domain of unknown function (DUF4201) M16C_assoc PF08367.11 KKK24986.1 - 3.2e-71 239.4 0.0 4.6e-71 238.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.21 KKK24986.1 - 2.6e-18 66.7 0.0 2.1e-11 44.2 0.0 2.7 3 0 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 KKK24986.1 - 2.7e-10 40.4 0.0 1.9e-09 37.7 0.0 2.3 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Pex14_N PF04695.13 KKK24989.1 - 0.076 13.7 2.8 0.12 13.0 2.8 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SARAF PF06682.12 KKK24989.1 - 0.13 11.8 5.4 0.18 11.4 5.4 1.3 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis DUF2076 PF09849.9 KKK24989.1 - 1.9 8.5 17.4 4.9 7.1 17.0 1.8 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) SNARE PF05739.19 KKK24989.1 - 3.1 7.9 5.4 1.7 8.7 1.9 2.0 2 0 0 2 2 2 0 SNARE domain EspB PF05802.11 KKK24989.1 - 3.8 7.5 5.4 26 4.7 5.4 2.1 1 1 0 1 1 1 0 Enterobacterial EspB protein CoA_transf_3 PF02515.17 KKK24990.1 - 2e-67 227.9 0.0 6e-67 226.3 0.0 1.6 1 1 0 1 1 1 1 CoA-transferase family III Sugar_tr PF00083.24 KKK24991.1 - 3.2e-84 283.4 28.7 3.9e-84 283.1 28.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKK24991.1 - 6e-11 41.9 44.6 1.4e-09 37.3 16.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.18 KKK24992.1 - 2.1e-66 223.7 0.1 2.9e-66 223.2 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 KKK24992.1 - 1.1e-05 25.6 11.7 0.0011 19.3 1.4 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KKK24992.1 - 0.031 15.1 9.9 0.19 12.6 1.2 3.1 2 0 0 2 2 2 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KKK24992.1 - 0.2 12.2 10.3 0.079 13.4 2.0 2.8 2 0 0 2 2 2 0 Zinc-finger double domain Ogr_Delta PF04606.12 KKK24992.1 - 1.3 9.0 3.8 1.3 9.0 0.8 2.3 1 1 1 2 2 2 0 Ogr/Delta-like zinc finger EF-hand_9 PF14658.6 KKK24993.1 - 3.7e-11 43.2 0.0 4e-05 23.8 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 KKK24993.1 - 7.9e-11 42.3 0.1 2.3e-06 27.9 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KKK24993.1 - 6.2e-09 35.1 0.1 0.013 15.3 0.0 3.3 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 KKK24993.1 - 3.4e-08 32.5 0.0 0.07 12.7 0.0 3.6 3 1 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 KKK24993.1 - 5.1e-07 29.4 0.1 3.8e-05 23.4 0.0 3.0 3 0 0 3 3 3 1 EF-hand domain pair DUF3216 PF11505.8 KKK24993.1 - 0.036 14.3 0.0 0.061 13.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3216) DUF3246 PF11596.8 KKK24994.1 - 0.0003 20.3 2.7 0.00058 19.4 2.7 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3246) Pox_Ag35 PF03286.14 KKK24994.1 - 0.02 14.7 2.2 0.02 14.7 2.2 2.3 3 0 0 3 3 3 0 Pox virus Ag35 surface protein PRCC PF10253.9 KKK24994.1 - 0.021 15.6 0.1 0.021 15.6 0.1 2.2 2 0 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting FAM176 PF14851.6 KKK24994.1 - 0.18 11.5 8.5 0.094 12.4 0.6 2.4 3 0 0 3 3 3 0 FAM176 family Presenilin PF01080.17 KKK24994.1 - 0.25 10.1 0.3 0.29 9.8 0.3 1.3 1 0 0 1 1 1 0 Presenilin TLP-20 PF06088.11 KKK24994.1 - 0.46 10.3 5.9 0.81 9.6 3.7 2.1 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) CENP-B_dimeris PF09026.10 KKK24994.1 - 0.96 9.9 7.9 0.62 10.5 2.1 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain TRAP_alpha PF03896.16 KKK24994.1 - 1.6 7.9 4.2 0.49 9.5 1.0 1.7 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit Ribosomal_60s PF00428.19 KKK24994.1 - 1.8 9.2 18.7 3.1 8.5 3.3 2.8 2 0 0 2 2 2 0 60s Acidic ribosomal protein RPN2_C PF18004.1 KKK24994.1 - 3.8 7.4 8.5 1.6 8.7 3.0 2.3 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain KCT2 PF17818.1 KKK24994.1 - 4.1 7.5 7.2 9.6 6.3 7.2 1.5 1 0 0 1 1 1 0 Keratinocyte-associated gene product DUF2967 PF11179.8 KKK24994.1 - 4.8 5.1 17.5 0.066 11.3 7.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2967) MOSC PF03473.17 KKK24995.1 - 1.4e-19 70.4 0.0 4.6e-19 68.7 0.0 1.8 2 0 0 2 2 2 1 MOSC domain MOSC_N PF03476.16 KKK24995.1 - 1.3e-09 38.0 0.0 3e-09 36.8 0.0 1.6 1 1 0 1 1 1 1 MOSC N-terminal beta barrel domain DUF3446 PF11928.8 KKK24995.1 - 3.7 7.9 13.6 12 6.3 1.6 2.6 2 0 0 2 2 2 0 Early growth response N-terminal domain Rad51 PF08423.11 KKK24996.1 - 2e-13 50.2 0.0 5.1e-12 45.6 0.0 2.2 1 1 0 1 1 1 1 Rad51 RecA PF00154.21 KKK24996.1 - 4.8e-06 26.2 0.0 0.00013 21.6 0.0 2.2 2 0 0 2 2 2 1 recA bacterial DNA recombination protein ATPase PF06745.13 KKK24996.1 - 5.3e-06 25.9 0.0 1.1e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 KaiC DnaB_C PF03796.15 KKK24996.1 - 6.5e-06 25.7 0.0 0.0004 19.8 0.0 2.2 2 0 0 2 2 2 1 DnaB-like helicase C terminal domain AAA_25 PF13481.6 KKK24996.1 - 3e-05 23.7 0.3 0.0031 17.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 KKK24996.1 - 6.7e-05 22.7 0.0 0.00013 21.8 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA PF00004.29 KKK24996.1 - 0.0002 21.8 0.1 0.00061 20.2 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) CbiA PF01656.23 KKK24996.1 - 0.00032 20.8 0.0 0.00047 20.2 0.0 1.3 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_22 PF13401.6 KKK24996.1 - 0.00079 19.7 0.0 0.0024 18.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 KKK24996.1 - 0.0019 18.2 0.0 0.0027 17.7 0.0 1.4 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_16 PF13191.6 KKK24996.1 - 0.0019 18.6 0.0 0.0034 17.8 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.6 KKK24996.1 - 0.0045 16.7 0.0 0.0084 15.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 KKK24996.1 - 0.0097 15.7 0.0 0.018 14.8 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 KKK24996.1 - 0.026 14.9 0.0 0.44 10.9 0.0 2.5 2 1 0 2 2 2 0 RNA helicase AAA_31 PF13614.6 KKK24996.1 - 0.033 14.1 0.0 0.069 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KKK24996.1 - 0.045 13.9 0.0 0.12 12.5 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KKK24996.1 - 0.053 14.1 0.1 0.19 12.3 0.0 2.0 3 0 0 3 3 1 0 AAA domain AAA_11 PF13086.6 KKK24996.1 - 0.055 13.3 0.3 0.11 12.2 0.0 1.7 2 1 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KKK24996.1 - 0.093 13.2 0.0 0.22 12.0 0.0 1.5 1 1 0 1 1 1 0 ABC transporter PhoH PF02562.16 KKK24996.1 - 0.11 12.0 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein NB-ARC PF00931.22 KKK24996.1 - 0.11 11.6 0.0 0.2 10.8 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain APS_kinase PF01583.20 KKK24996.1 - 0.12 12.3 0.0 5.6 6.8 0.0 2.3 2 0 0 2 2 2 0 Adenylylsulphate kinase CLP1_P PF16575.5 KKK24996.1 - 0.13 12.0 0.0 0.33 10.7 0.0 1.6 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_35 PF14516.6 KKK24996.1 - 0.16 10.8 0.0 0.28 10.0 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain FA_desaturase PF00487.24 KKK24997.1 - 8.8e-19 68.3 14.3 8.8e-19 68.3 14.3 1.7 1 1 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 KKK24997.1 - 2.7e-17 62.7 0.7 6.7e-17 61.4 0.1 1.9 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Xan_ur_permease PF00860.20 KKK24998.1 - 7.7e-64 215.8 31.1 3e-63 213.8 31.1 1.7 1 1 0 1 1 1 1 Permease family RINGv PF12906.7 KKK24999.1 - 2.3e-09 37.2 3.6 6.7e-09 35.7 0.8 2.4 2 0 0 2 2 2 1 RING-variant domain PHD_4 PF16866.5 KKK24999.1 - 0.23 11.6 1.0 1.7 8.8 0.9 2.1 2 0 0 2 2 2 0 PHD-finger zf-RING_2 PF13639.6 KKK24999.1 - 1.3 9.4 4.2 3.9 7.9 1.2 2.2 2 0 0 2 2 2 0 Ring finger domain Amidohydro_2 PF04909.14 KKK25000.1 - 9e-34 117.6 0.3 2.9e-29 102.8 0.1 2.0 2 0 0 2 2 2 2 Amidohydrolase Proteasome PF00227.26 KKK25002.1 - 6e-57 192.2 0.0 3e-32 111.7 0.0 2.2 1 1 1 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.9 KKK25002.1 - 9.3e-11 41.2 0.1 3.1e-10 39.5 0.0 1.9 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature S4 PF01479.25 KKK25011.1 - 1e-12 47.6 0.1 1.9e-12 46.7 0.1 1.4 1 0 0 1 1 1 1 S4 domain Ribosomal_S4 PF00163.19 KKK25011.1 - 5.6e-08 33.6 0.2 7.3e-08 33.2 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain Occludin_ELL PF07303.13 KKK25011.1 - 0.05 14.3 0.1 0.1 13.3 0.1 1.6 1 0 0 1 1 1 0 Occludin homology domain PilP PF04351.13 KKK25011.1 - 0.081 12.9 0.0 0.13 12.2 0.0 1.5 1 1 0 1 1 1 0 Pilus assembly protein, PilP Evr1_Alr PF04777.13 KKK25012.1 - 3.3e-28 98.1 1.4 5.7e-28 97.3 1.4 1.4 1 0 0 1 1 1 1 Erv1 / Alr family SOBP PF15279.6 KKK25013.1 - 3.7 8.1 13.6 5.9 7.4 13.6 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein Adaptin_N PF01602.20 KKK25014.1 - 7.7e-138 460.3 5.9 9.7e-138 460.0 5.9 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KKK25014.1 - 1.6e-64 216.9 1.6 5.4e-60 202.1 0.3 2.6 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KKK25014.1 - 8.5e-19 67.7 2.6 1.2e-06 28.8 0.0 6.3 1 1 5 6 6 6 5 HEAT repeats HEAT PF02985.22 KKK25014.1 - 1.9e-12 46.3 7.3 0.023 14.9 0.0 7.7 8 0 0 8 8 7 2 HEAT repeat HEAT_EZ PF13513.6 KKK25014.1 - 0.00022 21.6 1.2 0.64 10.6 0.0 5.6 6 1 1 7 7 7 1 HEAT-like repeat CLASP_N PF12348.8 KKK25014.1 - 0.00025 20.7 0.1 2 7.9 0.0 4.1 2 1 2 4 4 4 2 CLASP N terminal Arm PF00514.23 KKK25014.1 - 0.0016 18.4 1.2 11 6.3 0.0 5.4 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat RTP1_C1 PF10363.9 KKK25014.1 - 0.011 15.9 0.4 1.9 8.7 0.0 4.0 2 2 2 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 UNC45-central PF11701.8 KKK25014.1 - 0.12 12.3 0.8 0.4 10.6 0.1 2.3 3 1 0 3 3 3 0 Myosin-binding striated muscle assembly central CAAP1 PF15335.6 KKK25014.1 - 0.41 11.2 3.2 0.36 11.4 0.1 2.4 3 0 0 3 3 2 0 Caspase activity and apoptosis inhibitor 1 Ribosomal_60s PF00428.19 KKK25014.1 - 1.4 9.5 13.7 8.8 7.0 0.6 3.8 3 0 0 3 3 3 0 60s Acidic ribosomal protein ADH_N PF08240.12 KKK25015.1 - 1.1e-19 70.3 5.0 1.9e-19 69.5 5.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KKK25015.1 - 4.4e-17 62.3 0.0 7.2e-17 61.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KKK25015.1 - 9.1e-08 33.2 0.0 1.4e-07 32.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 KKK25015.1 - 0.004 16.6 0.0 0.0061 15.9 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 KKK25015.1 - 0.017 14.4 0.0 0.03 13.6 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DUF983 PF06170.12 KKK25015.1 - 0.34 11.3 0.1 0.34 11.3 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF983) TBCC PF07986.12 KKK25016.1 - 1.1e-31 109.1 0.8 2e-31 108.2 0.8 1.5 1 0 0 1 1 1 1 Tubulin binding cofactor C TBCC_N PF16752.5 KKK25016.1 - 3.5e-08 33.9 0.2 5.6e-08 33.2 0.2 1.3 1 0 0 1 1 1 1 Tubulin-specific chaperone C N-terminal domain RTX PF02382.15 KKK25016.1 - 0.095 12.4 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 N-terminal domain in RTX protein Phytase-like PF13449.6 KKK25017.1 - 6.7e-39 134.5 0.0 1.4e-38 133.5 0.0 1.4 1 0 0 1 1 1 1 Esterase-like activity of phytase Coatomer_WDAD PF04053.14 KKK25019.1 - 1.2e-148 495.8 0.0 3.3e-148 494.5 0.0 1.6 2 0 0 2 2 2 1 Coatomer WD associated region COPI_C PF06957.11 KKK25019.1 - 5.6e-108 361.3 0.0 8.6e-108 360.7 0.0 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.32 KKK25019.1 - 1.5e-36 123.7 15.6 2.5e-07 31.3 0.2 7.4 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKK25019.1 - 9.8e-08 32.2 0.2 0.43 10.9 0.0 5.4 3 1 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KKK25019.1 - 0.049 12.3 6.5 5.5 5.5 0.0 3.9 2 1 1 4 4 4 0 Nucleoporin Nup120/160 LysR_substrate PF03466.20 KKK25019.1 - 0.093 12.1 0.0 0.21 10.9 0.0 1.5 1 0 0 1 1 1 0 LysR substrate binding domain Clathrin PF00637.20 KKK25019.1 - 0.1 12.5 0.5 1.3 8.9 0.0 2.8 3 0 0 3 3 3 0 Region in Clathrin and VPS Pro-kuma_activ PF09286.11 KKK25020.1 - 9.3e-41 139.4 0.2 2.1e-40 138.3 0.2 1.6 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 KKK25020.1 - 0.00032 20.1 0.0 0.00055 19.3 0.0 1.3 1 0 0 1 1 1 1 Subtilase family Lyase_8_N PF08124.11 KKK25020.1 - 0.12 11.3 0.0 0.18 10.7 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide lyase family 8, N terminal alpha-helical domain TLD PF07534.16 KKK25022.1 - 4.8e-17 62.5 0.0 5.7e-14 52.5 0.0 2.1 2 0 0 2 2 2 2 TLD CSN8_PSD8_EIF3K PF10075.9 KKK25023.1 - 2.3e-19 69.8 0.0 4.5e-19 68.9 0.0 1.4 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family Vps51 PF08700.11 KKK25025.1 - 9.9e-27 92.9 0.0 2.1e-26 91.8 0.0 1.6 1 0 0 1 1 1 1 Vps51/Vps67 COG5 PF10392.9 KKK25025.1 - 0.0013 18.9 0.0 0.0026 18.0 0.0 1.4 1 0 0 1 1 1 1 Golgi transport complex subunit 5 Dor1 PF04124.12 KKK25025.1 - 0.037 12.7 0.0 0.044 12.5 0.0 1.1 1 0 0 1 1 1 0 Dor1-like family THUMP PF02926.17 KKK25025.1 - 0.05 13.7 0.3 0.079 13.1 0.3 1.3 1 0 0 1 1 1 0 THUMP domain HeLo PF14479.6 KKK25025.1 - 0.062 13.1 0.3 0.099 12.5 0.3 1.5 1 1 0 1 1 1 0 Prion-inhibition and propagation FlgN PF05130.12 KKK25025.1 - 0.61 10.6 4.1 15 6.1 0.5 2.7 1 1 1 2 2 2 0 FlgN protein RMI1_N PF08585.12 KKK25026.1 - 2.5e-61 207.2 0.0 2.9e-61 207.0 0.0 1.0 1 0 0 1 1 1 1 RecQ mediated genome instability protein TPR_16 PF13432.6 KKK25027.1 - 2.7e-25 88.7 33.4 3.4e-05 24.4 2.2 11.5 10 2 1 12 12 12 5 Tetratricopeptide repeat TPR_17 PF13431.6 KKK25027.1 - 8.9e-22 75.9 8.0 0.75 10.3 0.0 13.4 14 0 0 14 14 14 5 Tetratricopeptide repeat TPR_2 PF07719.17 KKK25027.1 - 9.2e-20 69.1 50.0 0.059 13.5 0.2 16.0 19 0 0 19 19 16 6 Tetratricopeptide repeat TPR_1 PF00515.28 KKK25027.1 - 1.8e-17 62.3 31.5 0.017 14.9 0.0 14.6 16 2 1 17 17 16 5 Tetratricopeptide repeat TPR_14 PF13428.6 KKK25027.1 - 3.5e-17 61.6 38.4 0.03 15.1 0.0 16.1 15 5 5 20 20 15 3 Tetratricopeptide repeat TPR_8 PF13181.6 KKK25027.1 - 6.1e-17 60.4 23.7 0.4 11.0 0.1 13.0 14 0 0 14 14 12 4 Tetratricopeptide repeat TPR_19 PF14559.6 KKK25027.1 - 1.5e-15 57.5 16.2 0.024 15.2 0.0 10.6 10 2 2 12 12 10 3 Tetratricopeptide repeat TPR_11 PF13414.6 KKK25027.1 - 2.6e-12 46.2 19.8 0.0078 15.9 0.0 10.6 11 0 0 11 11 11 4 TPR repeat TPR_12 PF13424.6 KKK25027.1 - 3e-12 46.6 37.4 8.8e-07 29.1 0.8 10.8 8 3 3 13 13 11 3 Tetratricopeptide repeat TPR_7 PF13176.6 KKK25027.1 - 1.3e-08 34.3 16.0 0.00096 19.0 0.0 9.9 12 1 0 12 12 11 2 Tetratricopeptide repeat TPR_6 PF13174.6 KKK25027.1 - 7.5e-08 32.5 17.6 0.18 12.5 0.1 10.3 11 0 0 11 11 10 2 Tetratricopeptide repeat TPR_10 PF13374.6 KKK25027.1 - 2.4e-06 27.2 12.8 0.026 14.4 0.1 8.6 10 0 0 10 10 9 1 Tetratricopeptide repeat TPR_22 PF18833.1 KKK25027.1 - 0.0011 19.0 0.0 0.0036 17.4 0.0 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat Coatomer_E PF04733.14 KKK25027.1 - 0.0017 17.9 0.1 0.022 14.2 0.0 2.6 2 0 0 2 2 2 1 Coatomer epsilon subunit DUF2225 PF09986.9 KKK25027.1 - 0.0046 16.7 1.0 0.42 10.3 0.2 3.4 3 0 0 3 3 3 1 Uncharacterized protein conserved in bacteria (DUF2225) FAT PF02259.23 KKK25027.1 - 0.0087 15.3 11.6 1.3 8.1 2.2 4.7 5 0 0 5 5 5 1 FAT domain TPR_9 PF13371.6 KKK25027.1 - 0.0089 16.2 7.8 1.7 8.9 0.0 6.0 5 1 1 6 6 5 1 Tetratricopeptide repeat Tcf25 PF04910.14 KKK25027.1 - 0.027 13.5 0.1 0.72 8.9 0.0 2.6 2 0 0 2 2 2 0 Transcriptional repressor TCF25 TPR_4 PF07721.14 KKK25027.1 - 0.052 14.2 9.5 30 5.7 0.0 6.5 6 0 0 6 6 6 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KKK25027.1 - 0.13 12.5 15.4 4.9 7.5 0.0 6.3 6 1 1 7 7 5 0 Anaphase-promoting complex, cyclosome, subunit 3 Glyco_hydro_5_C PF18564.1 KKK25028.1 - 5e-20 71.8 0.0 1.1e-19 70.7 0.0 1.7 1 0 0 1 1 1 1 Glycoside hydrolase family 5 C-terminal domain Cellulase PF00150.18 KKK25028.1 - 7.9e-10 38.6 1.0 2.9e-08 33.5 0.6 2.7 2 1 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) Xpo1 PF08389.12 KKK25029.1 - 2.3e-10 40.7 5.2 1.9e-08 34.5 1.2 4.4 3 2 0 3 3 3 1 Exportin 1-like protein Arabinose_trans PF04602.12 KKK25029.1 - 0.023 13.6 0.0 0.04 12.7 0.0 1.3 1 0 0 1 1 1 0 Mycobacterial cell wall arabinan synthesis protein GRIM-19 PF06212.12 KKK25030.1 - 5e-22 78.3 0.2 1.8e-21 76.5 0.2 1.7 1 1 0 1 1 1 1 GRIM-19 protein tRNA_m1G_MT PF01746.21 KKK25031.1 - 3.5e-25 88.9 0.0 9.4e-25 87.5 0.0 1.7 1 1 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase Presenilin PF01080.17 KKK25031.1 - 0.54 9.0 1.2 0.57 8.9 1.2 1.2 1 0 0 1 1 1 0 Presenilin VID27 PF08553.10 KKK25032.1 - 1.1e-195 649.6 0.0 1.9e-195 648.9 0.0 1.3 1 0 0 1 1 1 1 VID27 C-terminal WD40-like domain VID27_N PF17748.1 KKK25032.1 - 6.9e-77 257.2 0.2 6.9e-77 257.2 0.2 2.7 2 1 0 2 2 2 1 VID27 N-terminal region VID27_PH PF17747.1 KKK25032.1 - 2.4e-46 156.5 2.0 7.2e-46 155.0 1.1 2.1 2 0 0 2 2 2 1 VID27 PH-like domain Spore_III_AB PF09548.10 KKK25032.1 - 0.87 9.7 3.8 2.2 8.3 3.8 1.6 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) Nop14 PF04147.12 KKK25032.1 - 1.9 6.6 13.9 3.3 5.8 13.9 1.3 1 0 0 1 1 1 0 Nop14-like family Thr_synth_N PF14821.6 KKK25033.1 - 4.1e-30 103.8 0.0 2.6e-29 101.2 0.0 2.3 2 0 0 2 2 2 1 Threonine synthase N terminus PALP PF00291.25 KKK25033.1 - 1.6e-12 47.4 0.0 4.7e-12 45.9 0.0 1.8 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF1366 PF07104.11 KKK25033.1 - 0.15 11.7 0.0 2.7 7.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1366) Glucan_synthase PF02364.15 KKK25034.1 - 0 1393.0 0.0 0 1392.6 0.0 1.1 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 KKK25034.1 - 1.9e-22 80.0 0.1 6e-22 78.4 0.1 1.9 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 Aminotran_1_2 PF00155.21 KKK25035.1 - 4.5e-39 134.6 0.0 5.6e-39 134.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Glyco_hydro_17 PF00332.18 KKK25036.1 - 1.5e-07 31.3 0.5 5.4e-07 29.5 0.1 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 17 Peripla_BP_4 PF13407.6 KKK25036.1 - 0.065 12.8 0.6 2.8 7.5 0.6 2.5 1 1 0 1 1 1 0 Periplasmic binding protein domain Laminin_II PF06009.12 KKK25037.1 - 0.014 15.4 5.7 0.77 9.8 1.6 2.5 2 0 0 2 2 2 0 Laminin Domain II DUF2730 PF10805.8 KKK25037.1 - 0.07 13.2 5.1 0.2 11.8 0.1 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF2730) XhlA PF10779.9 KKK25037.1 - 0.96 9.7 6.4 18 5.6 0.1 3.4 2 1 1 3 3 3 0 Haemolysin XhlA Occludin_ELL PF07303.13 KKK25037.1 - 1.6 9.5 6.5 6 7.7 0.4 3.1 2 2 2 4 4 4 0 Occludin homology domain COG6 PF06419.11 KKK25038.1 - 5.2e-210 698.9 0.3 5.9e-210 698.7 0.3 1.0 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 Tnp_DNA_bind PF14706.6 KKK25038.1 - 0.16 11.9 0.1 0.68 9.8 0.1 2.1 1 0 0 1 1 1 0 Transposase DNA-binding NIF3 PF01784.18 KKK25039.1 - 7.1e-41 140.4 0.0 1.7e-38 132.7 0.0 2.0 1 1 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) Glyco_hydro_72 PF03198.14 KKK25040.1 - 1.7e-128 428.4 4.9 2.2e-128 428.0 4.9 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.13 KKK25040.1 - 2.8e-22 79.2 5.7 2.8e-22 79.2 5.7 2.2 2 0 0 2 2 2 1 X8 domain SprT-like PF10263.9 KKK25041.1 - 2.8e-40 136.7 0.1 5.5e-40 135.7 0.1 1.5 1 0 0 1 1 1 1 SprT-like family Zn_ribbon_SprT PF17283.2 KKK25041.1 - 6.8e-11 41.9 4.0 1.4e-10 40.9 4.0 1.6 1 0 0 1 1 1 1 SprT-like zinc ribbon domain TMEM119 PF15724.5 KKK25041.1 - 0.026 14.6 0.7 0.026 14.6 0.7 2.9 4 0 0 4 4 4 0 TMEM119 family PRIMA1 PF16101.5 KKK25041.1 - 0.04 13.9 5.1 0.11 12.5 5.1 1.7 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 DUF4448 PF14610.6 KKK25041.1 - 0.052 13.3 0.2 0.098 12.4 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Zn-ribbon_8 PF09723.10 KKK25041.1 - 0.081 13.1 0.5 0.18 11.9 0.5 1.6 1 0 0 1 1 1 0 Zinc ribbon domain ADK_lid PF05191.14 KKK25041.1 - 0.19 11.7 1.0 0.52 10.3 1.0 1.8 1 0 0 1 1 1 0 Adenylate kinase, active site lid DUF4379 PF14311.6 KKK25041.1 - 0.28 11.6 3.2 0.97 9.9 3.2 2.0 1 0 0 1 1 1 0 Probable Zinc-ribbon domain Mut7-C PF01927.16 KKK25041.1 - 0.64 10.1 2.2 21 5.2 0.4 2.5 1 1 1 2 2 2 0 Mut7-C RNAse domain Mog1 PF04603.12 KKK25042.1 - 3.8e-28 98.6 0.0 2.3e-27 96.1 0.0 2.1 1 1 0 1 1 1 1 Ran-interacting Mog1 protein NYN PF01936.18 KKK25042.1 - 0.00011 22.7 0.0 0.00073 20.0 0.0 2.4 3 1 0 3 3 3 1 NYN domain HSP9_HSP12 PF04119.12 KKK25043.1 - 2.1e-28 98.5 11.8 3.4e-28 97.8 10.4 1.8 2 0 0 2 2 2 1 Heat shock protein 9/12 Tombus_movement PF05318.12 KKK25043.1 - 0.029 15.2 2.3 0.032 15.0 2.0 1.3 1 1 0 1 1 1 0 Tombusvirus movement protein YtxH PF12732.7 KKK25043.1 - 0.1 13.2 2.0 0.21 12.1 1.1 1.9 1 1 1 2 2 2 0 YtxH-like protein LSM PF01423.22 KKK25044.1 - 4.7e-07 29.4 0.0 6.5e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 LSM domain Arm PF00514.23 KKK25045.1 - 9.2e-74 241.5 30.3 6.8e-13 48.2 0.2 11.4 11 1 0 11 11 11 9 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 KKK25045.1 - 5.9e-19 68.2 14.2 8.5e-05 23.0 0.2 8.4 7 1 2 9 9 8 5 HEAT-like repeat HEAT_2 PF13646.6 KKK25045.1 - 4.1e-17 62.3 8.4 0.0023 18.3 0.1 6.9 4 2 1 6 6 6 4 HEAT repeats HEAT PF02985.22 KKK25045.1 - 2.4e-15 55.3 14.5 0.32 11.4 0.1 9.2 10 0 0 10 10 9 4 HEAT repeat Arm_2 PF04826.13 KKK25045.1 - 4e-11 42.9 5.8 6.3e-06 25.8 2.2 2.4 1 1 1 2 2 2 2 Armadillo-like KAP PF05804.12 KKK25045.1 - 1.5e-10 39.9 0.7 2.9e-10 39.0 0.7 1.4 1 0 0 1 1 1 1 Kinesin-associated protein (KAP) Adaptin_N PF01602.20 KKK25045.1 - 3.3e-10 39.2 8.4 1.9e-06 26.8 1.1 2.7 1 1 1 2 2 2 2 Adaptin N terminal region V-ATPase_H_N PF03224.14 KKK25045.1 - 1.5e-08 34.4 2.8 8.9e-05 21.9 1.5 2.8 2 1 1 3 3 3 2 V-ATPase subunit H V-ATPase_H_C PF11698.8 KKK25045.1 - 7e-05 22.9 2.3 6.4 6.9 0.0 4.9 2 1 5 7 7 7 1 V-ATPase subunit H DUF3361 PF11841.8 KKK25045.1 - 0.00015 21.7 7.1 2.1 8.3 0.2 4.1 2 1 3 5 5 5 3 Domain of unknown function (DUF3361) Cnd1 PF12717.7 KKK25045.1 - 0.00026 21.0 8.5 0.024 14.7 0.4 4.8 3 1 2 5 5 5 1 non-SMC mitotic condensation complex subunit 1 Atx10homo_assoc PF09759.9 KKK25045.1 - 0.00047 20.1 4.4 1.3 9.0 0.0 4.9 4 2 1 5 5 5 1 Spinocerebellar ataxia type 10 protein domain DUF5578 PF17741.1 KKK25045.1 - 0.00097 18.6 6.9 3.3 7.1 0.0 5.0 2 1 3 6 6 6 1 Family of unknown function (DUF5578) IFRD PF05004.13 KKK25045.1 - 0.0055 15.9 8.3 0.84 8.7 0.4 4.4 3 2 1 4 4 4 2 Interferon-related developmental regulator (IFRD) Proteasom_PSMB PF10508.9 KKK25045.1 - 0.0079 14.8 2.7 0.17 10.4 0.4 2.9 2 1 1 3 3 3 1 Proteasome non-ATPase 26S subunit HEAT_PBS PF03130.16 KKK25045.1 - 0.014 16.0 8.1 14 6.7 0.5 6.6 6 0 0 6 6 6 0 PBS lyase HEAT-like repeat UNC45-central PF11701.8 KKK25045.1 - 0.02 14.9 2.0 1.8 8.5 0.2 3.2 2 1 0 3 3 3 0 Myosin-binding striated muscle assembly central Vac14_Fab1_bd PF12755.7 KKK25045.1 - 0.047 14.3 0.1 2.4 8.8 0.1 3.3 1 1 2 3 3 3 0 Vacuolar 14 Fab1-binding region RTP1_C1 PF10363.9 KKK25045.1 - 0.059 13.6 2.7 75 3.6 0.0 4.4 3 1 1 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 ANAPC15 PF15243.6 KKK25045.1 - 0.078 13.4 0.2 0.17 12.3 0.2 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 DAP_B PF07930.12 KKK25045.1 - 0.17 11.9 0.0 0.3 11.0 0.0 1.3 1 0 0 1 1 1 0 D-aminopeptidase, domain B EXOSC1 PF10447.9 KKK25046.1 - 1.3e-29 102.9 1.2 2e-29 102.4 1.2 1.3 1 0 0 1 1 1 1 Exosome component EXOSC1/CSL4 ECR1_N PF14382.6 KKK25046.1 - 1.3e-10 40.8 0.4 2.2e-10 40.1 0.4 1.4 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region EFG_C PF00679.24 KKK25047.1 - 8.8e-08 32.1 0.0 2.2e-07 30.8 0.0 1.6 2 0 0 2 2 2 1 Elongation factor G C-terminus AA_permease_2 PF13520.6 KKK25048.1 - 6.8e-57 193.2 49.3 8.5e-57 192.9 49.3 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KKK25048.1 - 1e-19 70.5 37.1 1.4e-19 70.1 37.1 1.1 1 0 0 1 1 1 1 Amino acid permease Erg28 PF03694.13 KKK25048.1 - 0.087 13.2 2.0 0.67 10.4 0.3 2.8 2 0 0 2 2 2 0 Erg28 like protein DUF3844 PF12955.7 KKK25048.1 - 9.1 6.5 6.4 26 5.0 0.1 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF3844) AA_permease_2 PF13520.6 KKK25050.1 - 5.8e-50 170.4 47.0 1.3e-49 169.2 47.0 1.5 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KKK25050.1 - 1.4e-17 63.5 41.2 2.6e-17 62.6 41.2 1.4 1 1 0 1 1 1 1 Amino acid permease Meleagrin PF08189.11 KKK25051.1 - 0.041 13.6 1.4 0.041 13.6 1.4 2.4 2 0 0 2 2 2 0 Meleagrin/Cygnin family Bac_rhamnosid6H PF17389.2 KKK25052.1 - 5.6e-88 295.4 1.3 5.8e-83 278.9 0.2 2.4 2 1 1 3 3 3 2 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid_N PF08531.10 KKK25052.1 - 5.8e-51 172.7 0.7 1.5e-47 161.7 0.7 2.5 1 1 0 1 1 1 1 Alpha-L-rhamnosidase N-terminal domain Bac_rhamnosid PF05592.11 KKK25052.1 - 5.6e-33 113.0 0.0 1e-32 112.1 0.0 1.4 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase concanavalin-like domain Bac_rhamnosid_C PF17390.2 KKK25052.1 - 5.3e-15 55.0 0.1 2.3e-14 52.9 0.1 2.1 1 1 0 1 1 1 1 Bacterial alpha-L-rhamnosidase C-terminal domain Pro-kuma_activ PF09286.11 KKK25053.1 - 9.4e-38 129.7 0.0 2.2e-37 128.5 0.0 1.6 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 KKK25053.1 - 7.2e-09 35.3 0.1 1.4e-08 34.4 0.1 1.4 1 0 0 1 1 1 1 Subtilase family DNA_pol_A_exo1 PF01612.20 KKK25054.1 - 1.2e-12 47.9 0.0 4e-12 46.2 0.0 1.8 1 1 0 1 1 1 1 3'-5' exonuclease Dioxygenase_C PF00775.21 KKK25054.1 - 1.6e-06 27.7 0.0 3e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Dioxygenase SE PF08491.10 KKK25055.1 - 3.9e-95 318.0 0.0 4.8e-95 317.7 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.19 KKK25055.1 - 4.4e-07 29.5 0.1 0.00045 19.6 0.6 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 KKK25055.1 - 3.9e-06 26.7 0.1 7.3e-05 22.5 0.3 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.22 KKK25055.1 - 0.00065 18.9 0.2 0.035 13.2 0.3 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_8 PF13450.6 KKK25055.1 - 0.0013 18.9 0.6 0.0029 17.8 0.6 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 KKK25055.1 - 0.0017 17.8 0.7 0.0024 17.3 0.7 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 KKK25055.1 - 0.0033 16.7 0.5 0.046 13.0 0.1 2.1 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.14 KKK25055.1 - 0.0039 16.5 0.1 0.0065 15.7 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KKK25055.1 - 0.011 16.3 0.3 0.023 15.2 0.3 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KKK25055.1 - 0.011 14.8 1.8 0.02 14.0 1.8 1.4 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 KKK25055.1 - 0.038 12.7 0.2 0.069 11.8 0.2 1.4 1 0 0 1 1 1 0 HI0933-like protein ApbA PF02558.16 KKK25055.1 - 0.063 12.9 0.3 0.11 12.1 0.3 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Lycopene_cycl PF05834.12 KKK25055.1 - 0.072 12.1 2.5 0.058 12.4 0.5 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein ThiF PF00899.21 KKK25055.1 - 0.096 12.0 0.2 0.17 11.2 0.2 1.3 1 0 0 1 1 1 0 ThiF family GMC_oxred_N PF00732.19 KKK25055.1 - 0.14 11.5 0.5 8.4 5.7 0.1 2.3 2 0 0 2 2 2 0 GMC oxidoreductase PAP_assoc PF03828.19 KKK25056.1 - 6.7e-17 61.5 0.1 1.5e-16 60.4 0.1 1.6 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 KKK25056.1 - 3.4e-06 27.3 0.0 7.2e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 KKK25056.1 - 0.11 12.6 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase Ferrochelatase PF00762.19 KKK25057.1 - 3.5e-99 331.9 0.0 4.1e-99 331.7 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase PPR PF01535.20 KKK25058.1 - 0.00025 21.1 1.3 3.5 8.1 0.0 5.3 6 0 0 6 6 6 1 PPR repeat PPR_2 PF13041.6 KKK25058.1 - 0.016 15.4 0.3 20 5.4 0.1 4.0 4 0 0 4 4 4 0 PPR repeat family RHSP PF07999.11 KKK25058.1 - 0.058 12.2 0.0 0.36 9.6 0.0 1.9 2 0 0 2 2 2 0 Retrotransposon hot spot protein RPN7 PF10602.9 KKK25058.1 - 0.096 12.4 0.1 0.22 11.2 0.1 1.6 1 0 0 1 1 1 0 26S proteasome subunit RPN7 Ku PF02735.16 KKK25059.1 - 3.2e-42 144.5 0.0 5.7e-42 143.7 0.0 1.4 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 KKK25059.1 - 4e-36 124.8 0.0 5.6e-36 124.3 0.0 1.2 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.14 KKK25059.1 - 6.8e-28 97.2 2.3 1.8e-27 95.9 2.3 1.8 1 0 0 1 1 1 1 Ku70/Ku80 C-terminal arm VWA_2 PF13519.6 KKK25059.1 - 0.047 14.3 0.0 0.41 11.3 0.0 2.4 3 0 0 3 3 3 0 von Willebrand factor type A domain VWA PF00092.28 KKK25059.1 - 0.073 13.3 0.0 0.72 10.1 0.0 2.1 2 0 0 2 2 2 0 von Willebrand factor type A domain Ribosomal_L5_C PF00673.21 KKK25060.1 - 2.9e-31 107.5 0.0 6.5e-31 106.4 0.0 1.6 2 0 0 2 2 2 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 KKK25060.1 - 8.1e-07 29.3 0.1 1.6e-06 28.3 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L5 Pep3_Vps18 PF05131.14 KKK25061.1 - 1.3e-44 151.7 0.1 3.9e-44 150.1 0.0 1.9 2 0 0 2 2 2 1 Pep3/Vps18/deep orange family Clathrin PF00637.20 KKK25061.1 - 2.2e-10 40.6 3.2 8.6e-05 22.4 0.0 3.5 3 0 0 3 3 3 2 Region in Clathrin and VPS DUF2175 PF09943.9 KKK25061.1 - 0.00014 22.1 0.3 0.19 12.0 0.0 2.7 2 0 0 2 2 2 2 Uncharacterized protein conserved in archaea (DUF2175) Zn_ribbon_17 PF17120.5 KKK25061.1 - 0.00018 21.0 0.1 0.00038 20.0 0.1 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 KKK25061.1 - 0.0043 17.0 0.3 0.011 15.7 0.3 1.7 1 0 0 1 1 1 1 zinc-RING finger domain Vps39_2 PF10367.9 KKK25061.1 - 0.0081 16.6 0.0 0.022 15.2 0.0 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 zf-C3HC4_2 PF13923.6 KKK25061.1 - 0.0082 16.0 0.6 0.0082 16.0 0.6 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KKK25061.1 - 0.039 14.3 1.0 0.1 12.9 1.0 1.7 1 0 0 1 1 1 0 Ring finger domain zf-RING_UBOX PF13445.6 KKK25061.1 - 0.042 13.9 0.1 0.11 12.6 0.1 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_11 PF17123.5 KKK25061.1 - 0.049 13.4 6.8 0.027 14.2 4.4 1.9 2 0 0 2 2 2 0 RING-like zinc finger zf-rbx1 PF12678.7 KKK25061.1 - 0.11 12.8 0.3 0.44 10.9 0.4 1.9 2 0 0 2 2 1 0 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KKK25061.1 - 0.21 11.5 0.2 0.64 9.9 0.2 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3H2C3 PF17122.5 KKK25061.1 - 6.4 6.9 5.3 0.96 9.5 1.0 1.9 2 0 0 2 2 2 0 Zinc-finger UCH PF00443.29 KKK25062.1 - 1.5e-14 54.2 0.0 3.4e-14 53.0 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KKK25062.1 - 3.5e-14 53.1 0.0 1.3e-06 28.2 0.0 2.3 1 1 1 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase EnY2 PF10163.9 KKK25062.1 - 0.013 15.8 0.0 0.035 14.5 0.0 1.7 1 0 0 1 1 1 0 Transcription factor e(y)2 Peptidase_M16 PF00675.20 KKK25063.1 - 1.5e-21 76.9 0.0 3.1e-21 75.9 0.0 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 KKK25063.1 - 2.1e-15 57.2 0.0 3.4e-15 56.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase M16 inactive domain DUF530 PF04409.12 KKK25063.1 - 0.066 11.6 0.7 0.12 10.7 0.2 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF530) M16C_assoc PF08367.11 KKK25063.1 - 0.076 12.1 0.0 0.14 11.2 0.0 1.4 1 0 0 1 1 1 0 Peptidase M16C associated RNA_pol_Rpc82 PF05645.13 KKK25064.1 - 8.3e-24 84.7 0.0 2.1e-21 76.8 0.0 2.4 2 0 0 2 2 2 2 RNA polymerase III subunit RPC82 HTH_9 PF08221.11 KKK25064.1 - 1.6e-15 57.0 1.6 6.9e-09 35.7 0.0 3.6 4 0 0 4 4 4 3 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.17 KKK25064.1 - 3.8e-06 26.7 0.3 0.0023 17.8 0.1 2.5 2 0 0 2 2 2 2 TFIIE alpha subunit Sas6_CC PF18594.1 KKK25064.1 - 0.021 14.6 0.4 0.046 13.5 0.4 1.6 1 0 0 1 1 1 0 Sas6/XLF/XRCC4 coiled-coil domain TFIIA PF03153.13 KKK25064.1 - 0.22 11.5 0.7 0.36 10.8 0.7 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit HLH PF00010.26 KKK25065.1 - 2.3e-14 53.1 0.2 4.5e-14 52.2 0.2 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain CorA PF01544.18 KKK25079.1 - 4.4e-08 32.8 0.1 6.2e-08 32.3 0.1 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein RadC PF04002.15 KKK25079.1 - 0.2 11.6 0.3 3 7.8 0.1 2.4 2 0 0 2 2 2 0 RadC-like JAB domain ApoL PF05461.11 KKK25079.1 - 6.5 6.0 8.3 0.054 12.8 0.4 1.5 2 0 0 2 2 2 0 Apolipoprotein L MFS_1 PF07690.16 KKK25096.1 - 7.3e-38 130.4 49.6 1e-37 129.9 45.6 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KKK25096.1 - 8.6e-13 47.6 15.2 8.6e-13 47.6 15.2 1.8 1 1 1 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF4514 PF14986.6 KKK25096.1 - 0.81 9.7 3.5 1.6 8.8 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4514) RTA1 PF04479.13 KKK25097.1 - 2.5e-45 154.7 9.6 2.5e-45 154.7 9.6 2.0 2 1 0 2 2 2 1 RTA1 like protein PHO4 PF01384.20 KKK25097.1 - 0.0086 15.2 2.2 0.0094 15.0 0.0 1.9 2 0 0 2 2 2 1 Phosphate transporter family DUF3382 PF11862.8 KKK25097.1 - 5 7.5 8.1 0.33 11.2 1.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3382) BRI3BP PF14965.6 KKK25097.1 - 6.4 6.3 7.9 1 8.8 0.3 2.3 2 0 0 2 2 2 0 Negative regulator of p53/TP53 FAD_binding_3 PF01494.19 KKK25098.1 - 7.9e-17 61.5 0.5 6.3e-12 45.4 0.6 2.3 2 1 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 KKK25098.1 - 7.1e-05 22.0 0.3 0.032 13.3 0.0 2.3 2 0 0 2 2 2 2 Lycopene cyclase protein SE PF08491.10 KKK25098.1 - 0.0034 16.5 0.0 0.046 12.8 0.0 2.0 2 0 0 2 2 2 1 Squalene epoxidase DAO PF01266.24 KKK25098.1 - 0.0043 16.7 0.2 1.1 8.8 0.0 2.3 1 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KKK25098.1 - 0.071 13.3 0.0 0.17 12.1 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain SUIM_assoc PF16619.5 KKK25098.1 - 0.11 12.6 6.6 0.2 11.7 6.6 1.3 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 HI0933_like PF03486.14 KKK25098.1 - 0.17 10.6 0.0 0.26 10.0 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein adh_short PF00106.25 KKK25099.1 - 1.5e-28 99.6 0.0 2.1e-28 99.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KKK25099.1 - 5.5e-23 81.8 0.0 9.7e-23 80.9 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KKK25099.1 - 4.7e-07 29.9 0.0 0.00043 20.2 0.0 2.2 2 0 0 2 2 2 2 KR domain Peptidase_S29 PF02907.15 KKK25099.1 - 0.13 12.0 0.3 0.21 11.3 0.3 1.3 1 0 0 1 1 1 0 Hepatitis C virus NS3 protease AreA_N PF07573.11 KKK25100.1 - 7.4e-23 81.0 9.0 7.4e-23 81.0 9.0 5.0 4 2 1 5 5 5 1 Nitrogen regulatory protein AreA N terminus GATA PF00320.27 KKK25100.1 - 3.9e-16 58.4 2.3 7.8e-16 57.4 2.3 1.5 1 0 0 1 1 1 1 GATA zinc finger DUF1752 PF08550.10 KKK25100.1 - 2.1e-12 46.6 2.2 4.1e-12 45.7 2.2 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Ipi1_N PF12333.8 KKK25101.1 - 3.8e-25 88.4 0.6 3.8e-25 88.4 0.6 1.9 2 1 0 2 2 2 1 Rix1 complex component involved in 60S ribosome maturation Zn_clus PF00172.18 KKK25102.1 - 2.3e-06 27.6 8.7 3.4e-06 27.1 8.7 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MGC-24 PF05283.11 KKK25102.1 - 0.059 13.8 0.4 0.13 12.8 0.4 1.5 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin ADH_zinc_N PF00107.26 KKK25103.1 - 8.4e-10 38.7 0.0 1.9e-09 37.6 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KKK25103.1 - 3e-05 25.1 0.0 6.5e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KKK25103.1 - 4.6e-05 23.3 0.6 0.00077 19.3 0.1 2.6 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain ketoacyl-synt PF00109.26 KKK25104.1 - 3.3e-75 252.9 0.0 5.9e-75 252.1 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain AMP-binding PF00501.28 KKK25104.1 - 1.2e-74 251.4 0.2 2.8e-74 250.2 0.1 1.7 2 0 0 2 2 2 1 AMP-binding enzyme Condensation PF00668.20 KKK25104.1 - 3.3e-60 204.1 0.0 5.7e-60 203.3 0.0 1.3 1 0 0 1 1 1 1 Condensation domain KR PF08659.10 KKK25104.1 - 1.1e-50 172.1 0.3 5.2e-50 169.9 0.1 2.3 3 0 0 3 3 2 1 KR domain PS-DH PF14765.6 KKK25104.1 - 3.5e-44 151.2 0.0 5.6e-44 150.6 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 KKK25104.1 - 1.3e-43 149.7 0.2 2.6e-43 148.8 0.2 1.5 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KKK25104.1 - 6e-30 103.7 0.0 1.5e-29 102.4 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain NAD_binding_4 PF07993.12 KKK25104.1 - 2.5e-28 98.9 0.0 8.3e-28 97.2 0.0 1.9 2 0 0 2 2 2 1 Male sterility protein Methyltransf_12 PF08242.12 KKK25104.1 - 6.9e-22 78.1 0.1 3.1e-21 75.9 0.0 2.3 2 0 0 2 2 1 1 Methyltransferase domain PP-binding PF00550.25 KKK25104.1 - 2.6e-17 62.9 0.8 4.2e-07 30.2 0.3 3.3 3 0 0 3 3 3 2 Phosphopantetheine attachment site Methyltransf_25 PF13649.6 KKK25104.1 - 1.3e-13 51.5 0.0 5.9e-13 49.4 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 KKK25104.1 - 1.3e-13 51.4 0.0 4e-13 49.8 0.0 1.8 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_23 PF13489.6 KKK25104.1 - 8.1e-13 48.5 0.0 1.8e-12 47.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KKK25104.1 - 1.1e-12 48.4 0.1 4.7e-12 46.4 0.0 2.2 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KKK25104.1 - 5.5e-11 42.5 0.0 2.1e-10 40.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 KKK25104.1 - 7.4e-09 35.3 0.0 1.7e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family adh_short PF00106.25 KKK25104.1 - 3.3e-07 30.0 0.0 5.6e-06 25.9 0.0 2.7 3 0 0 3 3 3 1 short chain dehydrogenase Epimerase PF01370.21 KKK25104.1 - 5.2e-07 29.4 0.0 1e-05 25.2 0.0 2.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Thiolase_N PF00108.23 KKK25104.1 - 1.3e-06 27.9 0.2 4.2e-06 26.3 0.1 1.8 2 0 0 2 2 2 1 Thiolase, N-terminal domain NodS PF05401.11 KKK25104.1 - 5.4e-05 22.9 0.0 0.00012 21.8 0.0 1.5 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_16 PF10294.9 KKK25104.1 - 0.008 15.9 0.0 0.023 14.4 0.0 1.7 1 0 0 1 1 1 1 Lysine methyltransferase RrnaAD PF00398.20 KKK25104.1 - 0.013 14.6 0.0 0.027 13.6 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_33 PF10017.9 KKK25104.1 - 0.014 14.6 0.0 0.03 13.5 0.0 1.5 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent AMP-binding_C PF13193.6 KKK25104.1 - 0.056 14.4 0.0 0.18 12.8 0.0 2.0 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain Methyltransf_28 PF02636.17 KKK25104.1 - 0.06 13.0 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Zn_clus PF00172.18 KKK25111.1 - 0.018 15.2 6.9 0.042 14.0 6.9 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-BED PF02892.15 KKK25111.1 - 0.056 13.5 0.5 0.14 12.2 0.5 1.6 1 0 0 1 1 1 0 BED zinc finger DNA_pol_B_palm PF14792.6 KKK25112.1 - 2.5e-34 117.9 0.0 6.5e-34 116.6 0.0 1.7 2 0 0 2 2 2 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.6 KKK25112.1 - 1.6e-24 85.9 0.0 3.3e-24 84.8 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.9 KKK25112.1 - 1.8e-18 66.1 0.1 2.4e-17 62.5 0.0 2.5 2 0 0 2 2 2 1 Fingers domain of DNA polymerase lambda HHH_8 PF14716.6 KKK25112.1 - 7e-18 64.8 0.1 1.7e-17 63.5 0.1 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain NTP_transf_2 PF01909.23 KKK25112.1 - 0.013 15.7 0.0 0.031 14.6 0.0 1.6 1 0 0 1 1 1 0 Nucleotidyltransferase domain HHH_5 PF14520.6 KKK25112.1 - 0.016 15.8 0.0 9.8 6.9 0.0 2.5 2 0 0 2 2 2 0 Helix-hairpin-helix domain DBP10CT PF08147.12 KKK25112.1 - 0.022 15.0 1.0 0.045 14.0 1.0 1.5 1 0 0 1 1 1 0 DBP10CT (NUC160) domain CwfJ_C_1 PF04677.15 KKK25113.1 - 2.6e-30 104.8 0.0 4.7e-29 100.7 0.0 2.2 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.14 KKK25113.1 - 6.8e-27 94.2 0.0 6.8e-27 94.2 0.0 2.4 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 2 DUF3010 PF11215.8 KKK25113.1 - 0.25 11.6 1.5 11 6.3 0.3 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3010) 2-Hacid_dh_C PF02826.19 KKK25114.1 - 1.2e-23 83.3 0.0 2e-23 82.7 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KKK25114.1 - 2.1e-09 37.1 0.0 2.7e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain IlvN PF07991.12 KKK25114.1 - 0.086 12.4 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain F420_oxidored PF03807.17 KKK25114.1 - 0.12 13.0 0.0 0.34 11.5 0.0 1.8 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 KKK25114.1 - 0.12 12.6 0.0 0.2 11.8 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Peptidase_S8 PF00082.22 KKK25115.1 - 2e-31 109.3 16.1 5.9e-31 107.8 16.1 1.6 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 KKK25115.1 - 4.7e-19 68.9 0.3 8.5e-19 68.0 0.3 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 NUP PF06516.11 KKK25116.1 - 4.2e-81 272.6 6.8 2.5e-58 197.7 4.6 2.4 1 1 2 3 3 3 3 Purine nucleoside permease (NUP) ATP_bind_1 PF03029.17 KKK25117.1 - 6.9e-73 245.4 0.0 1.2e-72 244.6 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.27 KKK25117.1 - 8.6e-05 22.2 0.0 0.0035 16.9 0.0 2.8 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain MeaB PF03308.16 KKK25117.1 - 0.00015 20.8 0.0 0.055 12.4 0.0 2.3 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB NACHT PF05729.12 KKK25117.1 - 0.0013 18.6 0.0 0.0058 16.6 0.0 1.9 2 0 0 2 2 2 1 NACHT domain AAA_24 PF13479.6 KKK25117.1 - 0.0021 17.8 0.0 0.0048 16.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 KKK25117.1 - 0.0024 17.9 0.0 0.014 15.5 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase NB-ARC PF00931.22 KKK25117.1 - 0.0029 16.8 0.0 0.0062 15.7 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.6 KKK25117.1 - 0.0045 17.4 0.0 0.031 14.7 0.0 2.3 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KKK25117.1 - 0.005 17.1 0.0 0.019 15.2 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KKK25117.1 - 0.0057 16.8 0.0 0.017 15.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 KKK25117.1 - 0.0096 15.5 0.0 0.021 14.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region FeoB_N PF02421.18 KKK25117.1 - 0.011 15.2 0.0 0.26 10.8 0.0 2.5 3 0 0 3 3 3 0 Ferrous iron transport protein B G-alpha PF00503.20 KKK25117.1 - 0.015 14.5 0.0 0.47 9.6 0.0 2.5 3 0 0 3 3 3 0 G-protein alpha subunit Arf PF00025.21 KKK25117.1 - 0.016 14.7 0.0 3.6 7.0 0.0 3.2 3 0 0 3 3 3 0 ADP-ribosylation factor family AAA_30 PF13604.6 KKK25117.1 - 0.016 14.9 0.0 0.038 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain CobT PF06213.12 KKK25117.1 - 0.017 14.5 9.2 0.026 13.9 9.2 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT PRK PF00485.18 KKK25117.1 - 0.018 14.8 0.0 0.044 13.5 0.0 1.6 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Roc PF08477.13 KKK25117.1 - 0.021 15.0 0.0 1.6 9.0 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase cobW PF02492.19 KKK25117.1 - 0.025 14.2 0.0 1.8 8.1 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Methyltransf_32 PF13679.6 KKK25117.1 - 0.033 14.2 0.4 0.07 13.1 0.4 1.6 1 1 0 1 1 1 0 Methyltransferase domain RsgA_GTPase PF03193.16 KKK25117.1 - 0.036 14.0 0.1 12 5.8 0.0 3.0 3 0 0 3 3 3 0 RsgA GTPase SRP54 PF00448.22 KKK25117.1 - 0.059 13.0 0.0 0.35 10.5 0.0 2.2 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain TsaE PF02367.17 KKK25117.1 - 0.16 12.0 0.0 0.33 11.0 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 KKK25117.1 - 0.2 12.2 0.4 0.56 10.8 0.0 2.0 2 0 0 2 2 1 0 AAA domain p53-inducible11 PF14936.6 KKK25117.1 - 0.29 11.2 3.9 0.13 12.3 1.0 1.8 2 0 0 2 2 2 0 Tumour protein p53-inducible protein 11 ACBP PF00887.19 KKK25119.1 - 2e-21 76.0 0.0 3.9e-21 75.1 0.0 1.5 1 0 0 1 1 1 1 Acyl CoA binding protein SDA1 PF05285.12 KKK25119.1 - 0.11 12.0 11.6 0.14 11.5 11.6 1.2 1 0 0 1 1 1 0 SDA1 TraP PF07296.11 KKK25119.1 - 0.16 11.2 2.0 0.29 10.3 2.0 1.3 1 0 0 1 1 1 0 TraP protein Nop14 PF04147.12 KKK25119.1 - 0.31 9.2 12.5 0.26 9.4 11.5 1.4 2 0 0 2 2 2 0 Nop14-like family CDC45 PF02724.14 KKK25119.1 - 0.39 8.9 12.3 0.56 8.4 12.3 1.1 1 0 0 1 1 1 0 CDC45-like protein SURF2 PF05477.11 KKK25119.1 - 0.56 9.9 4.5 0.95 9.1 4.5 1.3 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) BUD22 PF09073.10 KKK25119.1 - 5.9 6.1 11.9 9.8 5.4 11.9 1.3 1 0 0 1 1 1 0 BUD22 tRNA-synt_2d PF01409.20 KKK25133.1 - 2.1e-47 161.7 0.4 1.2e-25 90.4 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.14 KKK25133.1 - 1.3e-28 99.2 0.0 4.4e-28 97.5 0.0 1.9 2 0 0 2 2 2 1 Ferredoxin-fold anticodon binding domain GrpE PF01025.19 KKK25134.1 - 2.6e-39 134.6 5.3 3.6e-39 134.1 5.3 1.2 1 0 0 1 1 1 1 GrpE Mito_carr PF00153.27 KKK25135.1 - 7.1e-59 195.8 0.4 3.4e-19 68.5 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein RPA43_OB PF17875.1 KKK25136.1 - 5e-41 140.2 6.7 1.6e-40 138.5 0.0 2.9 2 1 0 2 2 2 1 RPA43 OB domain in RNA Pol I SHS2_Rpb7-N PF03876.17 KKK25136.1 - 1.7e-07 31.5 0.0 3.3e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 Mucin PF01456.17 KKK25136.1 - 0.0024 17.8 5.7 0.0024 17.8 5.7 2.5 2 0 0 2 2 2 1 Mucin-like glycoprotein Dicty_REP PF05086.12 KKK25136.1 - 0.0046 15.0 1.5 0.0046 15.0 1.5 2.0 2 0 0 2 2 2 1 Dictyostelium (Slime Mold) REP protein Tim54 PF11711.8 KKK25136.1 - 0.036 12.9 5.1 0.17 10.6 1.3 2.1 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 Ctr PF04145.15 KKK25136.1 - 0.077 13.6 1.0 21 5.7 0.0 2.3 2 0 0 2 2 2 0 Ctr copper transporter family DUF3439 PF11921.8 KKK25136.1 - 0.74 9.8 14.0 0.25 11.3 7.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Zip PF02535.22 KKK25136.1 - 2.7 7.1 5.4 0.35 10.0 1.0 1.6 2 0 0 2 2 2 0 ZIP Zinc transporter HNF-1_N PF04814.13 KKK25136.1 - 4.2 7.9 14.7 0.23 12.0 1.4 2.2 2 0 0 2 2 2 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus DUF4834 PF16118.5 KKK25136.1 - 4.9 8.2 8.5 6 7.9 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) U79_P34 PF03064.16 KKK25136.1 - 4.9 6.4 10.5 19 4.5 0.0 2.3 2 0 0 2 2 2 0 HSV U79 / HCMV P34 NPR3 PF03666.13 KKK25136.1 - 5.8 5.6 14.4 1.2 7.9 7.6 2.0 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 AJAP1_PANP_C PF15298.6 KKK25136.1 - 6.6 6.9 12.0 0.32 11.2 5.4 2.0 2 0 0 2 2 2 0 AJAP1/PANP C-terminus CPSF100_C PF13299.6 KKK25136.1 - 6.7 6.9 13.2 28 4.9 7.5 2.6 3 0 0 3 3 3 0 Cleavage and polyadenylation factor 2 C-terminal Arrestin_N PF00339.29 KKK25137.1 - 3e-14 53.3 0.2 2.6e-12 47.0 0.1 3.0 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Rgp1 PF08737.10 KKK25137.1 - 0.066 12.4 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 Rgp1 Bul1_C PF04426.12 KKK25137.1 - 0.077 12.4 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 Bul1 C terminus F-box-like PF12937.7 KKK25138.1 - 0.0048 16.8 0.2 0.013 15.4 0.2 1.7 1 0 0 1 1 1 1 F-box-like V-ATPase_G PF03179.15 KKK25139.1 - 6e-29 100.7 17.1 7.2e-29 100.4 17.1 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit S_layer_C PF05124.12 KKK25139.1 - 0.0079 16.2 2.3 0.0091 16.0 2.3 1.0 1 0 0 1 1 1 1 S-layer like family, C-terminal region ATP-synt_B PF00430.18 KKK25139.1 - 0.008 16.3 11.2 0.008 16.3 11.2 2.0 1 1 1 2 2 2 1 ATP synthase B/B' CF(0) ECM11 PF15463.6 KKK25139.1 - 0.1 13.2 11.1 0.19 12.3 11.1 1.5 1 1 0 1 1 1 0 Extracellular mutant protein 11 AAA_15 PF13175.6 KKK25139.1 - 0.13 11.9 6.2 0.15 11.8 6.2 1.0 1 0 0 1 1 1 0 AAA ATPase domain DUF1834 PF08873.11 KKK25139.1 - 0.16 11.7 0.9 0.2 11.4 0.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1834) DUF3552 PF12072.8 KKK25139.1 - 0.37 10.2 20.4 0.018 14.4 11.9 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) Clathrin_lg_ch PF01086.17 KKK25139.1 - 0.41 10.7 15.7 0.45 10.5 15.7 1.0 1 0 0 1 1 1 0 Clathrin light chain DUF5401 PF17380.2 KKK25139.1 - 1.3 7.0 14.9 1.5 6.8 14.9 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5401) V-ATPase_G_2 PF16999.5 KKK25139.1 - 3.8 8.0 18.8 6.9 7.2 18.8 1.4 1 1 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit DUF883 PF05957.13 KKK25139.1 - 4 8.1 9.1 13 6.5 9.0 1.8 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) RRF PF01765.19 KKK25139.1 - 4.9 7.1 13.7 5.9 6.8 13.7 1.1 1 0 0 1 1 1 0 Ribosome recycling factor Palm_thioest PF02089.15 KKK25140.1 - 0.04 13.7 0.0 0.056 13.3 0.0 1.4 1 1 0 1 1 1 0 Palmitoyl protein thioesterase Pyr_redox_2 PF07992.14 KKK25141.1 - 1.8e-41 142.3 0.0 2.7e-41 141.7 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.26 KKK25141.1 - 9.5e-16 57.5 0.1 2e-15 56.5 0.1 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pyr_redox PF00070.27 KKK25141.1 - 4.5e-09 36.7 0.0 2.1e-07 31.4 0.0 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Rieske_2 PF13806.6 KKK25141.1 - 2.8e-05 24.0 0.0 9.1e-05 22.3 0.0 1.9 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Reductase_C PF14759.6 KKK25141.1 - 4.9e-05 23.8 0.0 0.00024 21.6 0.0 2.2 2 0 0 2 2 2 1 Reductase C-terminal NAD_binding_9 PF13454.6 KKK25141.1 - 0.029 14.4 1.3 13 5.7 0.0 3.2 3 0 0 3 3 3 0 FAD-NAD(P)-binding DUF1188 PF06690.11 KKK25141.1 - 0.033 13.8 0.1 0.076 12.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1188) DUF834 PF05754.14 KKK25141.1 - 1 9.4 3.3 6.5 6.9 0.1 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF834) Zn_clus PF00172.18 KKK25142.1 - 0.00032 20.8 2.8 0.00032 20.8 2.8 2.4 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KKK25142.1 - 0.00093 18.1 0.0 0.0014 17.5 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain PDEase_I PF00233.19 KKK25142.1 - 0.14 11.9 0.1 1.6 8.4 0.0 2.1 2 0 0 2 2 2 0 3'5'-cyclic nucleotide phosphodiesterase UCH_1 PF13423.6 KKK25142.1 - 0.35 10.4 1.1 0.6 9.6 1.1 1.3 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase Nucleopor_Nup85 PF07575.13 KKK25143.1 - 3.4e-19 68.8 0.0 5.7e-12 45.0 0.0 2.3 2 0 0 2 2 2 2 Nup85 Nucleoporin Myc_N PF01056.18 KKK25143.1 - 0.12 12.2 0.9 0.27 11.1 0.9 1.5 1 0 0 1 1 1 0 Myc amino-terminal region Cytomega_UL84 PF06284.11 KKK25143.1 - 0.15 10.5 1.9 0.25 9.8 1.9 1.3 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein BSP_II PF05432.11 KKK25143.1 - 1.7 8.3 9.9 0.13 12.0 4.9 1.6 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) PET117 PF15786.5 KKK25144.1 - 6.3e-23 80.8 1.7 7.3e-23 80.6 1.7 1.0 1 0 0 1 1 1 1 PET assembly of cytochrome c oxidase, mitochondrial EMC3_TMCO1 PF01956.16 KKK25144.1 - 0.03 14.0 0.3 0.034 13.9 0.3 1.1 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like DUF5639 PF18690.1 KKK25144.1 - 0.042 14.0 0.3 0.069 13.3 0.3 1.4 1 1 0 1 1 1 0 Family of unknown function (DUF5639) DUF3824 PF12868.7 KKK25144.1 - 0.058 14.1 0.1 0.07 13.8 0.1 1.1 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) IDO PF01231.18 KKK25145.1 - 2.4e-32 112.3 0.0 3.3e-32 111.8 0.0 1.2 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase LRR_4 PF12799.7 KKK25146.1 - 8.3e-09 35.6 11.5 0.092 13.2 0.3 6.9 4 2 4 8 8 8 2 Leucine Rich repeats (2 copies) TPR_2 PF07719.17 KKK25146.1 - 3.5e-07 29.8 4.3 0.058 13.5 0.3 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KKK25146.1 - 5.4e-06 26.0 3.0 0.85 9.6 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat F-box PF00646.33 KKK25146.1 - 9.7e-06 25.3 0.2 3.1e-05 23.7 0.2 1.9 1 0 0 1 1 1 1 F-box domain TPR_16 PF13432.6 KKK25146.1 - 8.3e-05 23.2 1.9 0.0088 16.7 0.1 2.5 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 KKK25146.1 - 0.00093 19.7 2.4 0.012 16.1 0.9 2.3 1 1 1 2 2 2 1 Tetratricopeptide repeat BTAD PF03704.17 KKK25146.1 - 0.0013 19.2 1.5 0.012 16.0 1.5 2.1 1 1 0 1 1 1 1 Bacterial transcriptional activator domain F-box-like PF12937.7 KKK25146.1 - 0.0038 17.1 0.1 0.0074 16.2 0.1 1.5 1 0 0 1 1 1 1 F-box-like TPR_12 PF13424.6 KKK25146.1 - 0.0042 17.4 4.2 0.4 11.0 0.3 3.1 1 1 0 2 2 2 1 Tetratricopeptide repeat LRR_8 PF13855.6 KKK25146.1 - 0.0088 15.8 7.1 12 5.8 0.1 5.4 3 3 1 4 4 4 0 Leucine rich repeat PRANC PF09372.10 KKK25146.1 - 0.0091 16.3 0.0 0.018 15.3 0.0 1.5 1 0 0 1 1 1 1 PRANC domain NARP1 PF12569.8 KKK25146.1 - 0.0092 14.9 1.6 0.013 14.5 1.6 1.1 1 0 0 1 1 1 1 NMDA receptor-regulated protein 1 DUF1207 PF06727.11 KKK25146.1 - 0.01 14.7 0.1 0.019 13.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1207) TPR_11 PF13414.6 KKK25146.1 - 0.039 13.6 1.7 0.51 10.1 0.1 2.8 1 1 2 3 3 3 0 TPR repeat LRR_1 PF00560.33 KKK25146.1 - 0.057 14.0 0.9 2.7e+02 2.8 0.0 5.8 8 0 0 8 8 4 0 Leucine Rich Repeat TPR_14 PF13428.6 KKK25146.1 - 0.071 14.0 2.6 11 7.2 0.2 3.2 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 KKK25146.1 - 0.11 12.4 0.1 7.7 6.5 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF742 PF05331.11 KKK25146.1 - 0.14 11.9 0.0 0.31 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF742) DUF1699 PF08004.11 KKK25146.1 - 0.16 11.6 0.3 20 4.9 0.0 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1699) TPR_9 PF13371.6 KKK25146.1 - 0.17 12.1 2.1 17 5.6 0.3 2.7 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 KKK25146.1 - 0.32 11.1 1.3 39 4.6 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat ADIP PF11559.8 KKK25147.1 - 9.6e-46 155.6 7.6 9.6e-46 155.6 7.6 2.9 3 0 0 3 3 3 1 Afadin- and alpha -actinin-Binding Golgin_A5 PF09787.9 KKK25147.1 - 0.0029 17.1 9.2 0.0029 17.1 9.2 2.3 3 1 0 3 3 3 1 Golgin subfamily A member 5 APG6_N PF17675.1 KKK25147.1 - 0.0058 17.2 5.0 0.0058 17.2 5.0 4.0 3 2 0 3 3 2 1 Apg6 coiled-coil region DUF641 PF04859.12 KKK25147.1 - 0.075 13.4 12.2 0.38 11.1 2.5 3.6 2 1 1 3 3 3 0 Plant protein of unknown function (DUF641) FlaC_arch PF05377.11 KKK25147.1 - 0.083 13.3 4.5 0.34 11.3 0.5 3.2 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) RepA_C PF04796.12 KKK25147.1 - 0.092 12.8 0.5 0.57 10.2 0.3 2.2 2 0 0 2 2 2 0 Plasmid encoded RepA protein KASH_CCD PF14662.6 KKK25147.1 - 0.095 12.5 14.8 0.033 14.0 9.5 2.4 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH DUF724 PF05266.14 KKK25147.1 - 0.11 12.4 10.3 0.029 14.2 5.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF724) AKNA PF12443.8 KKK25147.1 - 0.18 12.5 9.7 0.15 12.7 3.4 3.8 3 2 1 4 4 4 0 AT-hook-containing transcription factor DUF2304 PF10066.9 KKK25147.1 - 0.37 11.0 0.8 0.64 10.3 0.8 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2304) TMPIT PF07851.13 KKK25147.1 - 2.1 7.5 4.6 4.2 6.5 4.6 1.5 1 0 0 1 1 1 0 TMPIT-like protein V_ATPase_I PF01496.19 KKK25147.1 - 2.2 6.1 4.9 5.9 4.7 4.9 1.6 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Spc7 PF08317.11 KKK25147.1 - 6.3 5.6 17.0 0.077 11.9 7.6 2.4 3 0 0 3 3 3 0 Spc7 kinetochore protein VPS38 PF17649.1 KKK25147.1 - 7.7 5.3 7.5 6 5.6 3.3 2.1 1 1 1 2 2 2 0 Vacuolar protein sorting 38 DUF3886 PF13025.6 KKK25147.1 - 7.9 6.7 13.0 0.55 10.5 4.4 3.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3886) DUF3090 PF11290.8 KKK25147.1 - 8 6.2 8.1 1.4 8.7 0.5 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3090) DUF948 PF06103.11 KKK25147.1 - 8.9 6.6 10.0 2.9 8.2 0.7 3.7 2 2 1 4 4 4 0 Bacterial protein of unknown function (DUF948) adh_short PF00106.25 KKK25148.1 - 1e-42 145.8 0.1 1.3e-42 145.4 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KKK25148.1 - 1.1e-28 100.4 0.0 1.3e-28 100.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KKK25148.1 - 0.00011 22.1 0.0 0.00016 21.7 0.0 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 KKK25148.1 - 0.00079 18.9 0.0 0.0019 17.6 0.0 1.5 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.6 KKK25148.1 - 0.0069 16.3 0.0 0.012 15.6 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KKK25148.1 - 0.0076 15.8 0.1 0.037 13.6 0.0 2.0 3 0 0 3 3 3 1 NmrA-like family ADH_zinc_N PF00107.26 KKK25148.1 - 0.011 15.8 0.0 0.17 11.9 0.0 2.1 2 0 0 2 2 2 0 Zinc-binding dehydrogenase Epimerase PF01370.21 KKK25148.1 - 0.015 14.8 0.0 0.023 14.2 0.0 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.19 KKK25148.1 - 0.084 12.2 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F-box PF00646.33 KKK25149.1 - 1.3e-06 28.1 3.5 1.3e-06 28.1 1.2 2.1 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KKK25149.1 - 1.6e-06 27.9 0.6 3.8e-06 26.7 0.6 1.6 1 0 0 1 1 1 1 F-box-like HSF_DNA-bind PF00447.17 KKK25150.1 - 3.8e-30 104.4 0.7 6.7e-30 103.6 0.7 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding Lipase_GDSL PF00657.22 KKK25150.1 - 0.11 12.5 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase Phasin PF05597.11 KKK25151.1 - 0.13 12.2 0.0 24 4.9 0.0 2.6 3 0 0 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF3439 PF11921.8 KKK25151.1 - 4.6 7.2 6.8 15 5.5 6.8 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Ribosomal_L13e PF01294.18 KKK25152.1 - 2.5e-49 167.5 1.3 3.1e-48 164.0 1.3 2.6 1 1 0 1 1 1 1 Ribosomal protein L13e DUF3245 PF11595.8 KKK25153.1 - 7e-53 179.1 8.2 7e-53 179.1 8.2 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF3245) Nucleo_P87 PF07267.11 KKK25153.1 - 0.43 9.4 2.9 0.51 9.1 2.9 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Myc_N PF01056.18 KKK25153.1 - 3.7 7.3 6.4 6.9 6.5 6.1 1.6 1 1 0 1 1 1 0 Myc amino-terminal region BLOC1S3 PF15753.5 KKK25153.1 - 5.2 7.2 8.1 30 4.7 7.2 2.2 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 CDC45 PF02724.14 KKK25153.1 - 6.8 4.8 9.8 7.9 4.6 9.8 1.3 1 0 0 1 1 1 0 CDC45-like protein Oxidored-like PF09791.9 KKK25154.1 - 8.2e-23 79.8 3.7 1.6e-22 78.9 3.7 1.5 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal DUF5522 PF17653.1 KKK25154.1 - 0.071 13.1 3.1 0.15 12.1 3.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5522) LRR_4 PF12799.7 KKK25155.1 - 8.1e-25 86.5 39.4 8.1e-06 26.1 2.2 9.9 5 3 5 11 11 11 11 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KKK25155.1 - 9.4e-23 79.8 39.5 1.5e-07 31.1 4.4 8.1 4 3 4 8 8 8 8 Leucine rich repeat LRR_1 PF00560.33 KKK25155.1 - 1.4e-05 25.0 33.3 1.6 9.6 0.1 10.9 11 0 0 11 11 11 3 Leucine Rich Repeat LRR_6 PF13516.6 KKK25155.1 - 1.6e-05 24.6 25.5 1.3 9.2 0.1 10.1 11 0 0 11 11 11 4 Leucine Rich repeat LRR_9 PF14580.6 KKK25155.1 - 0.0067 16.0 15.9 0.065 12.7 1.2 4.2 3 2 2 5 5 5 2 Leucine-rich repeat GCIP PF13324.6 KKK25156.1 - 1.4e-19 70.7 3.6 1.9e-19 70.3 3.6 1.1 1 0 0 1 1 1 1 Grap2 and cyclin-D-interacting VSG_B PF13206.6 KKK25156.1 - 0.0023 17.3 0.7 0.0032 16.8 0.7 1.3 1 0 0 1 1 1 1 Trypanosomal VSG domain Sigma70_ner PF04546.13 KKK25156.1 - 0.011 15.6 5.6 0.011 15.6 5.6 1.7 2 0 0 2 2 2 0 Sigma-70, non-essential region RXT2_N PF08595.11 KKK25156.1 - 0.015 15.3 4.2 0.024 14.7 4.2 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal SDA1 PF05285.12 KKK25156.1 - 0.056 12.9 7.4 0.065 12.7 7.4 1.1 1 0 0 1 1 1 0 SDA1 LTV PF04180.14 KKK25156.1 - 0.069 12.9 8.5 0.087 12.5 8.5 1.1 1 0 0 1 1 1 0 Low temperature viability protein Nop14 PF04147.12 KKK25156.1 - 0.12 10.6 9.7 0.14 10.4 9.7 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 KKK25156.1 - 0.12 10.7 6.0 0.15 10.3 6.0 1.1 1 0 0 1 1 1 0 CDC45-like protein RRN3 PF05327.11 KKK25156.1 - 0.39 9.2 6.4 0.5 8.9 6.4 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 TRAP_alpha PF03896.16 KKK25156.1 - 0.45 9.7 4.0 0.57 9.3 4.0 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DNA_pol_phi PF04931.13 KKK25156.1 - 0.47 8.5 14.2 0.59 8.2 14.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi NOA36 PF06524.12 KKK25156.1 - 0.68 9.2 13.0 0.97 8.7 13.0 1.1 1 0 0 1 1 1 0 NOA36 protein RNA_pol_3_Rpc31 PF11705.8 KKK25156.1 - 0.69 10.1 13.1 0.93 9.7 13.1 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 YL1 PF05764.13 KKK25156.1 - 1.6 8.8 16.8 2.4 8.2 16.8 1.1 1 0 0 1 1 1 0 YL1 nuclear protein ATP-grasp_2 PF08442.10 KKK25157.1 - 1.7e-76 256.3 0.4 1.7e-76 256.3 0.4 1.7 2 0 0 2 2 2 1 ATP-grasp domain Ligase_CoA PF00549.19 KKK25157.1 - 4.1e-25 88.4 0.3 4.1e-25 88.4 0.3 1.8 2 0 0 2 2 2 1 CoA-ligase ATP-grasp_5 PF13549.6 KKK25157.1 - 1e-08 34.9 0.4 3e-08 33.4 0.4 1.7 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 KKK25157.1 - 0.00013 21.8 1.4 0.0071 16.1 0.1 2.7 2 1 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Succ_CoA_lig PF13607.6 KKK25157.1 - 0.041 13.7 0.3 14 5.5 0.0 3.1 2 1 1 3 3 3 0 Succinyl-CoA ligase like flavodoxin domain VID27_N PF17748.1 KKK25157.1 - 0.14 12.0 0.6 0.27 11.1 0.6 1.4 1 0 0 1 1 1 0 VID27 N-terminal region Gryzun PF07919.12 KKK25158.1 - 7.8e-233 774.5 0.0 9.6e-233 774.3 0.0 1.1 1 0 0 1 1 1 1 Gryzun, putative trafficking through Golgi Foie-gras_1 PF11817.8 KKK25158.1 - 1.3e-114 382.2 1.8 3.3e-105 351.4 2.0 2.7 3 0 0 3 3 3 2 Foie gras liver health family 1 Abhydrolase_1 PF00561.20 KKK25159.1 - 9.2e-09 35.3 0.0 2.3e-08 34.0 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KKK25159.1 - 2.1e-07 30.5 0.0 1e-06 28.2 0.0 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KKK25159.1 - 5e-07 30.5 2.2 2.5e-06 28.3 2.2 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family PEMT PF04191.13 KKK25160.1 - 3.1e-33 114.3 1.3 6.9e-33 113.2 1.3 1.6 1 0 0 1 1 1 1 Phospholipid methyltransferase YrhK PF14145.6 KKK25160.1 - 0.02 14.7 0.6 0.093 12.6 0.1 2.2 2 0 0 2 2 2 0 YrhK-like protein RXT2_N PF08595.11 KKK25161.1 - 1.2e-42 145.6 0.1 1.2e-42 145.6 0.1 2.3 2 0 0 2 2 2 1 RXT2-like, N-terminal Thioredoxin PF00085.20 KKK25162.1 - 1.1e-22 80.0 0.2 4.1e-17 62.1 0.4 2.4 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.6 KKK25162.1 - 0.00045 20.6 0.1 0.0032 17.9 0.1 2.2 1 1 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.21 KKK25162.1 - 0.01 15.7 0.1 0.032 14.1 0.1 1.8 2 0 0 2 2 2 0 AhpC/TSA family Thioredoxin_8 PF13905.6 KKK25162.1 - 0.012 16.0 0.0 0.27 11.6 0.0 2.7 3 1 0 3 3 3 0 Thioredoxin-like Thioredoxin_3 PF13192.6 KKK25162.1 - 0.14 12.2 0.2 7.6 6.7 0.3 2.4 2 0 0 2 2 2 0 Thioredoxin domain OST3_OST6 PF04756.13 KKK25162.1 - 0.17 11.2 0.0 0.48 9.7 0.0 1.7 2 0 0 2 2 2 0 OST3 / OST6 family, transporter family F-box PF00646.33 KKK25163.1 - 1.4e-07 31.2 0.1 5.4e-07 29.3 0.1 2.0 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KKK25163.1 - 1.2e-06 28.3 0.2 1.2e-06 28.3 0.2 2.2 3 0 0 3 3 3 1 F-box-like Sugar_tr PF00083.24 KKK25164.1 - 1e-101 341.1 14.9 1.9e-101 340.2 14.6 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKK25164.1 - 2.4e-20 72.8 37.0 9.7e-12 44.5 11.3 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3723 PF12520.8 KKK25165.1 - 0.017 13.9 0.6 0.026 13.2 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3723) GNAT_acetyltr_2 PF13718.6 KKK25166.1 - 7.7e-98 326.4 0.0 1.3e-97 325.7 0.0 1.4 1 0 0 1 1 1 1 GNAT acetyltransferase 2 tRNA_bind_2 PF13725.6 KKK25166.1 - 5.3e-94 314.3 0.0 9.9e-94 313.4 0.0 1.5 1 0 0 1 1 1 1 Possible tRNA binding domain Helicase_RecD PF05127.14 KKK25166.1 - 8.3e-66 221.2 0.0 2.4e-65 219.7 0.0 1.8 2 0 0 2 2 2 1 Helicase DUF1726 PF08351.11 KKK25166.1 - 5.2e-34 116.1 0.0 1.5e-33 114.6 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) AAA_30 PF13604.6 KKK25166.1 - 0.00035 20.4 0.0 0.079 12.7 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KKK25166.1 - 0.0084 16.4 0.0 0.19 12.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain Acetyltransf_1 PF00583.25 KKK25166.1 - 0.034 14.4 0.0 0.21 11.8 0.0 2.3 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family Svs_4_5_6 PF17381.2 KKK25166.1 - 0.2 12.7 2.7 0.44 11.5 2.7 1.6 1 0 0 1 1 1 0 Seminal vesicle secretory proteins 4/5/6 ATP-synt PF00231.19 KKK25167.1 - 8.7e-62 209.4 3.9 1.9e-61 208.3 3.9 1.4 1 1 0 1 1 1 1 ATP synthase Topoisom_I_N PF02919.15 KKK25168.1 - 2e-94 315.0 1.8 2e-94 315.0 1.8 3.3 3 0 0 3 3 3 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.20 KKK25168.1 - 2.1e-94 315.2 9.9 2.1e-94 315.2 9.9 2.0 2 0 0 2 2 2 1 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.6 KKK25168.1 - 1e-33 115.0 1.0 3.4e-33 113.4 1.0 2.0 1 0 0 1 1 1 1 C-terminal topoisomerase domain Pkinase PF00069.25 KKK25171.1 - 8.1e-57 192.6 0.0 1.1e-56 192.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK25171.1 - 1.3e-41 142.6 0.0 1.9e-41 142.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KKK25171.1 - 4.4e-05 22.4 0.6 0.00012 21.0 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 KKK25171.1 - 0.00012 21.5 0.0 0.00018 20.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KKK25171.1 - 0.00062 19.8 0.0 0.0033 17.4 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KKK25171.1 - 0.0041 16.5 0.3 0.015 14.7 0.1 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 KKK25171.1 - 0.015 15.0 0.0 0.037 13.7 0.0 1.6 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 KKK25171.1 - 0.078 11.9 0.1 0.25 10.3 0.0 1.7 2 0 0 2 2 2 0 Haspin like kinase domain RIO1 PF01163.22 KKK25171.1 - 0.28 10.7 2.1 0.55 9.8 0.2 2.3 2 1 0 2 2 2 0 RIO1 family Pet191_N PF10203.9 KKK25172.1 - 4.3e-28 97.4 4.4 5.4e-28 97.1 4.4 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 COBRA PF04833.15 KKK25172.1 - 0.01 15.8 0.2 0.011 15.7 0.2 1.1 1 0 0 1 1 1 0 COBRA-like protein Cmc1 PF08583.10 KKK25172.1 - 0.2 11.7 2.5 2.3 8.3 0.2 2.4 1 1 0 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like Glyco_hydro_75 PF07335.11 KKK25173.1 - 2.7e-37 128.6 0.0 2.5e-35 122.2 0.0 2.5 1 1 0 1 1 1 1 Fungal chitosanase of glycosyl hydrolase group 75 Abhydrolase_1 PF00561.20 KKK25174.1 - 1.5e-25 90.3 0.0 2.5e-25 89.6 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydro_lipase PF04083.16 KKK25174.1 - 8.8e-23 79.7 0.2 2e-22 78.5 0.0 1.7 2 0 0 2 2 2 1 Partial alpha/beta-hydrolase lipase region Hydrolase_4 PF12146.8 KKK25174.1 - 1.1e-05 24.8 0.0 0.0085 15.4 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 FSH1 PF03959.13 KKK25174.1 - 0.018 14.7 0.0 2.9 7.5 0.0 2.1 2 0 0 2 2 2 0 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 KKK25174.1 - 0.19 11.5 0.1 15 5.3 0.0 2.3 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Ras PF00071.22 KKK25175.1 - 4.4e-31 107.7 2.0 4.4e-28 97.9 0.0 2.1 2 0 0 2 2 2 2 Ras family Roc PF08477.13 KKK25175.1 - 7.2e-08 32.7 1.5 3.4e-05 24.1 0.0 2.3 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKK25175.1 - 0.00028 20.4 0.1 0.0056 16.1 0.0 2.1 2 0 0 2 2 2 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 KKK25175.1 - 0.002 18.0 0.1 2 8.3 0.1 2.2 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 KKK25175.1 - 0.06 13.7 0.6 0.16 12.3 0.6 1.9 1 1 0 1 1 1 0 AAA ATPase domain GTP_EFTU PF00009.27 KKK25175.1 - 0.071 12.6 0.0 2 7.9 0.0 2.2 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain FtsK_SpoIIIE PF01580.18 KKK25175.1 - 0.3 10.4 1.3 1.7 7.9 1.3 2.0 1 1 0 1 1 1 0 FtsK/SpoIIIE family DDOST_48kD PF03345.14 KKK25176.1 - 7e-148 492.9 0.0 9.1e-148 492.5 0.0 1.1 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta AAA_11 PF13086.6 KKK25180.1 - 4.9e-62 210.1 0.4 2e-61 208.1 0.4 2.0 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.6 KKK25180.1 - 4.3e-57 193.0 0.0 7.2e-57 192.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KKK25180.1 - 1e-13 51.5 0.0 1.7e-12 47.5 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KKK25180.1 - 5.9e-09 36.4 0.0 2e-08 34.7 0.0 2.0 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 KKK25180.1 - 2.9e-07 30.5 0.0 0.057 13.1 0.0 3.3 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.9 KKK25180.1 - 1.3e-05 24.6 0.3 0.00013 21.4 0.3 2.2 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Helicase_RecD PF05127.14 KKK25180.1 - 7.7e-05 22.6 0.0 0.17 11.8 0.0 2.9 3 0 0 3 3 3 2 Helicase ResIII PF04851.15 KKK25180.1 - 8.4e-05 22.6 0.0 0.00028 21.0 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.21 KKK25180.1 - 0.00042 20.0 0.2 0.0031 17.1 0.3 2.2 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA_22 PF13401.6 KKK25180.1 - 0.00048 20.4 0.2 0.015 15.6 0.2 2.6 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 KKK25180.1 - 0.00058 19.4 0.0 0.022 14.2 0.0 2.6 2 0 0 2 2 2 1 PhoH-like protein DEAD PF00270.29 KKK25180.1 - 0.00064 19.5 0.1 0.0088 15.8 0.1 2.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase Flavi_DEAD PF07652.14 KKK25180.1 - 0.002 18.1 0.1 0.015 15.3 0.1 2.3 2 0 0 2 2 2 1 Flavivirus DEAD domain T2SSE PF00437.20 KKK25180.1 - 0.0028 16.8 0.0 0.0048 16.0 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein UvrD_C_2 PF13538.6 KKK25180.1 - 0.0035 17.1 0.1 0.24 11.2 0.0 2.4 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA PF00004.29 KKK25180.1 - 0.0077 16.7 0.0 0.04 14.3 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 KKK25180.1 - 0.0081 15.9 0.0 0.034 13.9 0.0 2.0 3 0 0 3 3 2 1 IstB-like ATP binding protein AAA_16 PF13191.6 KKK25180.1 - 0.0099 16.3 0.1 0.024 15.0 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.6 KKK25180.1 - 0.015 15.0 0.0 0.04 13.6 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KKK25180.1 - 0.019 14.5 0.3 0.28 10.8 0.0 2.8 2 2 1 3 3 3 0 AAA domain UvrD_C PF13361.6 KKK25180.1 - 0.023 14.1 0.1 6.3 6.1 0.0 3.0 2 1 0 3 3 3 0 UvrD-like helicase C-terminal domain 4HB_MCP_1 PF12729.7 KKK25180.1 - 0.053 13.1 0.1 0.11 12.1 0.1 1.4 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction AAA_5 PF07728.14 KKK25180.1 - 0.059 13.4 0.1 0.81 9.7 0.0 2.8 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) PSK_trans_fac PF07704.11 KKK25180.1 - 0.059 14.1 1.4 5.9 7.7 1.7 2.7 2 0 0 2 2 2 0 Rv0623-like transcription factor TrwB_AAD_bind PF10412.9 KKK25180.1 - 0.068 12.1 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain PIF1 PF05970.14 KKK25180.1 - 0.13 11.4 0.0 4.7 6.3 0.0 2.4 2 1 0 2 2 2 0 PIF1-like helicase Herpes_ori_bp PF02399.15 KKK25180.1 - 0.14 10.1 0.0 0.24 9.4 0.0 1.2 1 0 0 1 1 1 0 Origin of replication binding protein Allexi_40kDa PF05549.11 KKK25181.1 - 0.0029 17.2 6.0 0.052 13.0 1.1 2.4 2 0 0 2 2 2 2 Allexivirus 40kDa protein PIG-F PF06699.11 KKK25182.1 - 1.7e-65 220.6 2.2 2.1e-65 220.2 2.2 1.1 1 0 0 1 1 1 1 GPI biosynthesis protein family Pig-F RhoGAP PF00620.27 KKK25183.1 - 9e-39 132.7 0.0 1.5e-38 132.0 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain Arf PF00025.21 KKK25184.1 - 2.7e-71 238.6 0.2 3e-71 238.4 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KKK25184.1 - 6.7e-16 58.6 0.1 9e-16 58.2 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 KKK25184.1 - 2.7e-13 49.8 1.6 3.6e-09 36.2 0.4 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 KKK25184.1 - 6.1e-13 48.7 0.0 6.8e-13 48.5 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 KKK25184.1 - 3.4e-10 39.6 0.0 4.2e-10 39.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 KKK25184.1 - 1.1e-09 38.0 0.0 1.2e-09 37.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KKK25184.1 - 2.1e-05 24.6 0.0 2.9e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KKK25184.1 - 0.014 15.0 0.8 0.025 14.1 0.4 1.6 1 1 0 1 1 1 0 Ferrous iron transport protein B 6PF2K PF01591.18 KKK25184.1 - 0.018 14.4 0.3 0.039 13.3 0.1 1.6 2 0 0 2 2 2 0 6-phosphofructo-2-kinase Glycos_transf_1 PF00534.20 KKK25185.1 - 1e-14 54.5 0.0 2.9e-14 53.0 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KKK25185.1 - 6.1e-13 49.4 0.0 1.2e-12 48.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 KKK25185.1 - 0.00019 21.7 0.0 0.00043 20.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 DUF3646 PF12362.8 KKK25185.1 - 0.13 12.6 0.0 0.29 11.5 0.0 1.5 1 0 0 1 1 1 0 DNA polymerase III gamma and tau subunits C terminal MIP PF00230.20 KKK25186.1 - 2.4e-33 115.7 3.6 3.4e-33 115.2 3.6 1.2 1 0 0 1 1 1 1 Major intrinsic protein Fungal_trans_2 PF11951.8 KKK25186.1 - 3.1e-19 69.0 4.4 5.8e-19 68.2 4.4 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK25186.1 - 7.9e-08 32.3 8.9 1.5e-07 31.4 8.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gly-zipper_Omp PF13488.6 KKK25186.1 - 5.6 7.0 5.2 5.5 7.1 1.0 2.7 2 1 0 2 2 2 0 Glycine zipper Voldacs PF03517.13 KKK25187.1 - 0.11 12.6 6.3 0.37 10.9 6.3 1.9 1 1 0 1 1 1 0 Regulator of volume decrease after cellular swelling BSP_II PF05432.11 KKK25187.1 - 0.12 12.0 9.2 0.22 11.2 9.2 1.3 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Myc_N PF01056.18 KKK25187.1 - 0.17 11.8 3.4 0.32 10.8 3.4 1.4 1 0 0 1 1 1 0 Myc amino-terminal region RPN2_C PF18004.1 KKK25187.1 - 0.22 11.4 3.6 0.44 10.5 3.6 1.4 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain DUF3043 PF11241.8 KKK25187.1 - 0.25 11.3 0.5 0.45 10.5 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) GOLD_2 PF13897.6 KKK25187.1 - 0.39 11.2 1.8 66 4.0 0.0 2.5 2 0 0 2 2 2 0 Golgi-dynamics membrane-trafficking RNA_pol_3_Rpc31 PF11705.8 KKK25187.1 - 2.2 8.5 9.7 5.1 7.3 9.7 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 NOA36 PF06524.12 KKK25187.1 - 7.7 5.7 6.8 12 5.1 6.8 1.2 1 0 0 1 1 1 0 NOA36 protein DUF726 PF05277.12 KKK25222.1 - 3.6e-129 430.6 2.0 5.2e-129 430.1 2.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Abhydrolase_8 PF06259.12 KKK25222.1 - 0.054 13.1 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase RTC4 PF14474.6 KKK25223.1 - 8.1e-33 113.2 0.0 1.7e-32 112.1 0.0 1.5 1 0 0 1 1 1 1 RTC4-like domain Rad54_N PF08658.10 KKK25223.1 - 0.035 14.3 3.4 0.05 13.8 1.6 2.2 1 1 1 2 2 2 0 Rad54 N terminal zf-MIZ PF02891.20 KKK25223.1 - 0.087 12.6 0.9 0.15 11.8 0.9 1.4 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger Menin PF05053.13 KKK25223.1 - 7.3 4.8 7.3 11 4.3 7.3 1.3 1 0 0 1 1 1 0 Menin adh_short PF00106.25 KKK25230.1 - 2.1e-12 46.9 0.0 2.4e-12 46.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KKK25230.1 - 1.1e-11 45.0 0.0 1.2e-11 44.8 0.0 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 KKK25230.1 - 1.9e-09 37.4 0.0 2.2e-09 37.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase TPR_17 PF13431.6 KKK25251.1 - 0.00055 20.1 0.5 1 9.9 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 KKK25251.1 - 0.022 14.5 2.8 0.25 11.1 0.0 3.8 4 0 0 4 4 4 0 TPR repeat TPR_12 PF13424.6 KKK25251.1 - 0.8 10.0 9.9 3.7 7.9 0.1 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Nnf1 PF03980.14 KKK25252.1 - 3.5e-33 114.3 2.7 3.5e-33 114.3 2.7 1.8 2 0 0 2 2 2 1 Nnf1 Spc42p PF11544.8 KKK25252.1 - 0.026 14.5 1.4 0.069 13.1 0.1 2.3 2 1 1 3 3 3 0 Spindle pole body component Spc42p ZNRF_3_ecto PF18212.1 KKK25252.1 - 0.13 12.3 1.1 10 6.1 0.3 2.3 2 0 0 2 2 2 0 ZNRF-3 Ectodomain DUF1348 PF07080.11 KKK25286.1 - 7.9e-56 187.5 2.5 9.4e-56 187.3 2.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1348) SnoaL_2 PF12680.7 KKK25286.1 - 3.6e-06 27.6 0.1 7.8e-06 26.5 0.1 1.6 1 1 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 KKK25286.1 - 2.6e-05 24.6 0.0 3.6e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) Zn_clus PF00172.18 KKK25287.1 - 6e-09 35.9 7.4 8.5e-09 35.4 7.4 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.25 KKK25288.1 - 6.5e-66 222.4 0.0 2.5e-65 220.5 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Fungal_KA1 PF16797.5 KKK25288.1 - 3.3e-37 126.8 0.1 5.9e-37 126.0 0.1 1.4 1 0 0 1 1 1 1 Fungal kinase associated-1 domain Pkinase_Tyr PF07714.17 KKK25288.1 - 8.9e-36 123.5 0.0 3.6e-34 118.2 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KKK25288.1 - 0.00019 21.4 0.2 0.0097 15.9 0.1 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KKK25288.1 - 0.00021 20.4 0.0 0.0005 19.1 0.0 1.5 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KKK25288.1 - 0.00035 20.0 0.0 0.00061 19.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 KKK25288.1 - 0.023 14.3 0.0 0.059 13.0 0.0 1.6 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kinase-like PF14531.6 KKK25288.1 - 0.066 12.5 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Redoxin PF08534.10 KKK25289.1 - 9e-36 122.8 0.0 1e-35 122.6 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 KKK25289.1 - 2.9e-13 49.8 0.0 3.8e-13 49.4 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family DUF1690 PF07956.11 KKK25290.1 - 2.2e-39 135.1 6.8 3e-19 69.8 0.3 2.0 2 0 0 2 2 2 2 Protein of Unknown function (DUF1690) ARA70 PF12489.8 KKK25290.1 - 0.0015 18.8 0.2 0.0024 18.1 0.2 1.3 1 0 0 1 1 1 1 Nuclear coactivator Rootletin PF15035.6 KKK25290.1 - 0.009 16.0 0.9 0.31 11.0 0.1 2.2 2 0 0 2 2 2 1 Ciliary rootlet component, centrosome cohesion cwf21 PF08312.12 KKK25290.1 - 0.016 15.3 4.9 3.2 8.0 4.3 2.4 2 0 0 2 2 2 0 cwf21 domain Apolipoprotein PF01442.18 KKK25290.1 - 0.028 14.3 8.9 0.51 10.2 3.2 2.2 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain Plasmid_RAQPRD PF09686.10 KKK25290.1 - 0.036 14.3 0.1 0.16 12.2 0.0 2.1 2 1 0 2 2 2 0 Plasmid protein of unknown function (Plasmid_RAQPRD) Herpes_UL25 PF01499.16 KKK25290.1 - 0.038 12.5 0.2 0.043 12.3 0.2 1.1 1 0 0 1 1 1 0 Herpesvirus UL25 family MRP-S26 PF14943.6 KKK25290.1 - 0.24 11.3 7.1 0.054 13.4 2.8 1.9 2 0 0 2 2 2 0 Mitochondrial ribosome subunit S26 Med9 PF07544.13 KKK25290.1 - 0.28 11.3 3.3 0.35 11.0 0.0 2.4 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 CdvA PF18822.1 KKK25290.1 - 0.71 9.7 6.8 0.63 9.9 0.7 2.4 3 0 0 3 3 3 0 CdvA-like coiled-coil domain FliT PF05400.13 KKK25290.1 - 4.9 8.0 10.0 0.18 12.6 2.8 2.2 3 0 0 3 3 3 0 Flagellar protein FliT POP1 PF06978.11 KKK25291.1 - 2.5e-74 249.7 14.3 2.5e-74 249.7 14.3 1.9 3 0 0 3 3 3 1 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.12 KKK25291.1 - 1.2e-32 112.0 0.9 1.2e-32 112.0 0.9 2.3 2 0 0 2 2 2 1 POPLD (NUC188) domain Adeno_terminal PF02459.15 KKK25291.1 - 4.7 5.5 5.5 7.7 4.8 5.5 1.2 1 0 0 1 1 1 0 Adenoviral DNA terminal protein YTH PF04146.15 KKK25292.1 - 8e-59 198.3 0.0 2.5e-58 196.7 0.0 1.8 2 0 0 2 2 2 1 YT521-B-like domain RRM_1 PF00076.22 KKK25292.1 - 2.1e-06 27.5 0.0 3.9e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Spt5_N PF11942.8 KKK25292.1 - 0.023 15.7 0.9 0.023 15.7 0.9 2.9 4 0 0 4 4 4 0 Spt5 transcription elongation factor, acidic N-terminal Aminotran_1_2 PF00155.21 KKK25294.1 - 1.6e-49 169.0 0.0 1.9e-32 112.9 0.0 2.1 1 1 1 2 2 2 2 Aminotransferase class I and II Aminotran_5 PF00266.19 KKK25294.1 - 0.0071 15.3 0.0 0.011 14.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V AMP-binding PF00501.28 KKK25295.1 - 9e-38 129.9 0.0 1.4e-37 129.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 KKK25295.1 - 1.4e-11 44.1 1.0 4.1e-11 42.6 1.0 1.9 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 KKK25295.1 - 0.00029 21.8 0.0 0.0014 19.6 0.0 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain DUF4211 PF13926.6 KKK25296.1 - 3.8e-33 114.6 0.0 8.9e-33 113.4 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4211) DUF2046 PF09755.9 KKK25296.1 - 0.046 13.0 7.8 0.06 12.6 0.3 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein H4 (DUF2046) Toxin_14 PF07829.11 KKK25296.1 - 0.38 10.7 5.1 0.79 9.7 5.1 1.5 1 0 0 1 1 1 0 Alpha-A conotoxin PIVA-like protein HLH PF00010.26 KKK25298.1 - 1.7e-13 50.3 0.5 3.5e-13 49.3 0.5 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Sugar_tr PF00083.24 KKK25299.1 - 3.3e-100 336.1 23.2 3.8e-100 335.9 23.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKK25299.1 - 9e-30 103.8 30.0 8.5e-22 77.5 4.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1980 PF09323.10 KKK25299.1 - 0.01 15.8 0.0 0.032 14.2 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) IU_nuc_hydro PF01156.19 KKK25300.1 - 2.8e-12 46.8 0.0 3.7e-12 46.4 0.0 1.2 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase FMO-like PF00743.19 KKK25301.1 - 7.3e-13 47.8 0.0 2.2e-12 46.2 0.0 1.7 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KKK25301.1 - 6e-12 45.4 0.0 8.5e-10 38.3 0.1 3.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KKK25301.1 - 2.3e-08 34.2 0.4 2.9e-06 27.4 0.1 3.3 2 1 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KKK25301.1 - 1.9e-06 28.0 0.5 8.7e-05 22.7 0.0 2.9 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KKK25301.1 - 3.3e-06 26.6 0.1 0.035 13.3 0.1 3.8 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KKK25301.1 - 1.3e-05 24.5 0.0 0.0061 15.8 0.0 3.3 3 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 KKK25301.1 - 0.0011 19.5 0.1 1.4 9.5 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KKK25301.1 - 0.15 11.2 0.0 0.15 11.2 0.0 1.9 3 0 0 3 3 3 0 Thi4 family FAD_binding_3 PF01494.19 KKK25301.1 - 0.2 10.8 1.0 0.38 9.9 0.1 1.8 2 0 0 2 2 2 0 FAD binding domain Tom22 PF04281.13 KKK25302.1 - 3.1e-52 176.0 1.6 3.5e-52 175.9 1.6 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 Peptidase_M16_C PF05193.21 KKK25303.1 - 4.3e-55 186.6 0.0 1.5e-54 184.8 0.0 1.9 2 0 0 2 2 2 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 KKK25303.1 - 2.2e-42 144.6 0.0 9.6e-41 139.2 0.0 2.1 2 0 0 2 2 2 2 Insulinase (Peptidase family M16) Nup160 PF11715.8 KKK25304.1 - 1.1e-171 572.2 0.9 1.5e-171 571.7 0.9 1.2 1 0 0 1 1 1 1 Nucleoporin Nup120/160 ABC_tran PF00005.27 KKK25305.1 - 6.1e-41 140.2 0.0 9e-19 68.4 0.0 3.6 3 0 0 3 3 3 3 ABC transporter ABC_membrane PF00664.23 KKK25305.1 - 1.7e-24 87.0 22.9 1.3e-21 77.5 6.6 2.6 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 KKK25305.1 - 1.1e-08 34.8 0.3 0.0012 18.4 0.0 3.3 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 KKK25305.1 - 0.00016 21.6 0.1 0.00083 19.3 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase AAA PF00004.29 KKK25305.1 - 0.00041 20.8 0.3 0.032 14.7 0.0 3.7 5 0 0 5 5 5 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KKK25305.1 - 0.00074 19.9 0.0 0.048 14.0 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 KKK25305.1 - 0.0008 19.3 0.1 0.13 12.1 0.0 2.9 2 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KKK25305.1 - 0.0017 18.0 0.1 0.0058 16.4 0.1 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain RNA_helicase PF00910.22 KKK25305.1 - 0.0077 16.6 0.1 0.24 11.8 0.0 3.0 3 0 0 3 3 2 1 RNA helicase AAA_33 PF13671.6 KKK25305.1 - 0.0083 16.3 0.0 0.03 14.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.6 KKK25305.1 - 0.026 14.7 0.4 13 6.1 0.3 2.9 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.6 KKK25305.1 - 0.029 14.6 0.5 0.22 11.8 0.0 2.4 2 1 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 KKK25305.1 - 0.041 14.0 0.0 0.3 11.2 0.0 2.3 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_23 PF13476.6 KKK25305.1 - 0.044 14.3 0.2 0.096 13.2 0.2 1.4 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KKK25305.1 - 0.098 12.4 0.3 3.8 7.2 0.1 2.3 2 0 0 2 2 2 0 AAA domain DUF3290 PF11694.8 KKK25305.1 - 0.4 10.6 2.4 1.4 8.9 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3290) Rad51 PF08423.11 KKK25306.1 - 1.3e-128 427.7 0.0 1.7e-128 427.2 0.0 1.2 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.6 KKK25306.1 - 8.3e-10 38.6 0.0 1.8e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain RecA PF00154.21 KKK25306.1 - 5.5e-09 35.9 0.0 8.5e-09 35.3 0.0 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein HHH_5 PF14520.6 KKK25306.1 - 4.5e-05 24.0 0.4 0.00011 22.7 0.2 1.7 2 0 0 2 2 2 1 Helix-hairpin-helix domain ATPase PF06745.13 KKK25306.1 - 0.00015 21.2 1.2 0.00057 19.3 1.2 1.9 1 1 0 1 1 1 1 KaiC DnaB_C PF03796.15 KKK25306.1 - 0.025 13.9 0.1 0.12 11.6 0.0 1.9 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain PAXNEB PF05625.11 KKK25306.1 - 0.12 11.5 0.7 0.34 10.0 0.1 1.9 2 0 0 2 2 2 0 PAXNEB protein AMP-binding PF00501.28 KKK25307.1 - 1.4e-269 893.7 0.0 4.1e-74 249.7 0.0 5.1 4 1 0 4 4 4 4 AMP-binding enzyme Condensation PF00668.20 KKK25307.1 - 2.6e-251 834.1 0.0 3.1e-57 194.3 0.0 9.6 8 3 0 8 8 8 8 Condensation domain PP-binding PF00550.25 KKK25307.1 - 6.2e-48 161.0 0.0 1.4e-11 44.6 0.0 6.0 5 0 0 5 5 5 5 Phosphopantetheine attachment site Transferase PF02458.15 KKK25307.1 - 0.00057 18.7 0.0 1 7.9 0.0 3.7 4 0 0 4 4 4 2 Transferase family AMP-binding_C PF13193.6 KKK25307.1 - 0.0076 17.2 0.0 0.41 11.6 0.0 3.7 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain MFS_1 PF07690.16 KKK25308.1 - 5.3e-35 121.0 45.7 2.2e-32 112.3 18.1 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KKK25308.1 - 0.00014 20.4 2.6 0.00014 20.4 2.6 2.1 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) HLH PF00010.26 KKK25309.1 - 1.1e-07 31.6 1.2 2.1e-07 30.8 1.2 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF615 PF04751.14 KKK25309.1 - 0.022 14.7 1.2 0.034 14.1 1.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF615) DIOX_N PF14226.6 KKK25311.1 - 8.1e-25 87.9 0.1 1.2e-24 87.3 0.1 1.2 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KKK25311.1 - 1.1e-13 51.5 0.0 7.2e-13 48.9 0.0 2.3 2 1 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DUF3433 PF11915.8 KKK25312.1 - 1.4e-32 112.0 22.5 1.9e-18 66.7 3.6 3.7 4 0 0 4 4 4 2 Protein of unknown function (DUF3433) ABC2_membrane_2 PF12679.7 KKK25312.1 - 0.39 10.0 5.4 0.58 9.4 3.8 2.2 2 0 0 2 2 2 0 ABC-2 family transporter protein Glyco_hydro_61 PF03443.14 KKK25313.1 - 1.3e-39 136.3 0.0 2.5e-39 135.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 adh_short PF00106.25 KKK25314.1 - 1.9e-49 167.8 0.0 2.6e-49 167.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KKK25314.1 - 2e-39 135.6 0.0 2.5e-39 135.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KKK25314.1 - 3.7e-08 33.5 0.0 5.1e-08 33.0 0.0 1.1 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 KKK25314.1 - 5.1e-06 26.1 0.0 6.9e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 KKK25314.1 - 0.00023 20.7 0.1 0.00055 19.5 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KKK25314.1 - 0.0029 17.2 0.1 0.083 12.4 0.2 2.1 2 0 0 2 2 2 1 NmrA-like family Glyco_hydro_2_N PF02837.18 KKK25315.1 - 3.4e-11 43.4 0.2 1.1e-10 41.7 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.17 KKK25315.1 - 9.8e-09 34.7 0.1 8.2e-08 31.7 0.1 2.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2 PF00703.21 KKK25315.1 - 1.7e-08 35.1 2.0 2.8e-06 28.0 0.0 2.4 2 0 0 2 2 2 2 Glycosyl hydrolases family 2 Fungal_trans PF04082.18 KKK25317.1 - 1e-10 41.1 0.0 1.4e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_43 PF04616.14 KKK25318.1 - 9.8e-43 146.5 5.5 1.1e-42 146.3 5.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 ADH_N PF08240.12 KKK25319.1 - 3.6e-34 116.9 1.0 3.6e-34 116.9 1.0 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KKK25319.1 - 1.3e-23 83.4 0.3 2.1e-23 82.7 0.3 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KKK25319.1 - 3.5e-09 36.5 0.1 6.1e-09 35.7 0.1 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 KKK25319.1 - 0.00019 22.5 0.0 0.00041 21.4 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KKK25319.1 - 0.0015 17.9 0.7 0.0024 17.2 0.7 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.14 KKK25319.1 - 0.0095 15.5 0.0 0.016 14.8 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Methyltransf_25 PF13649.6 KKK25319.1 - 0.027 15.2 0.0 0.051 14.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Pyr_redox_2 PF07992.14 KKK25319.1 - 0.029 13.6 0.3 0.049 12.9 0.1 1.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 KKK25319.1 - 0.11 11.8 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PrmA PF06325.13 KKK25319.1 - 0.18 11.2 0.1 0.26 10.7 0.1 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Pyr_redox_3 PF13738.6 KKK25319.1 - 0.25 10.6 1.2 0.6 9.3 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase WD40 PF00400.32 KKK25320.1 - 0.0028 18.5 11.7 1.4 9.9 0.1 7.6 8 1 0 8 8 8 1 WD domain, G-beta repeat Nbas_N PF15492.6 KKK25320.1 - 0.06 12.7 0.0 3.6 6.8 0.0 2.5 2 0 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal PQQ_2 PF13360.6 KKK25320.1 - 0.079 12.5 0.8 14 5.2 0.0 3.2 3 1 1 4 4 4 0 PQQ-like domain FAD-oxidase_C PF02913.19 KKK25321.1 - 2.3e-60 204.3 0.1 3.7e-60 203.7 0.1 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 KKK25321.1 - 3.2e-35 120.9 0.0 7.8e-35 119.6 0.0 1.7 1 0 0 1 1 1 1 FAD binding domain Het-C PF07217.11 KKK25322.1 - 3e-241 801.9 0.0 3.7e-241 801.5 0.0 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C RNA_pol_N PF01194.17 KKK25323.1 - 1.1e-11 44.8 0.5 3e-11 43.4 0.5 1.8 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit XK-related PF09815.9 KKK25323.1 - 0.0017 17.5 0.2 0.0027 16.8 0.2 1.3 1 0 0 1 1 1 1 XK-related protein Fer4_13 PF13370.6 KKK25323.1 - 0.099 13.2 1.5 5.5 7.6 0.2 3.7 2 2 1 3 3 3 0 4Fe-4S single cluster domain of Ferredoxin I Clr5 PF14420.6 KKK25324.1 - 1.7e-13 50.5 0.9 8.3e-13 48.4 0.9 2.3 1 0 0 1 1 1 1 Clr5 domain YozE_SAM_like PF06855.12 KKK25324.1 - 0.21 11.8 1.0 24 5.2 0.1 2.6 2 0 0 2 2 2 0 YozE SAM-like fold Dioxygenase_N PF04444.14 KKK25325.1 - 4.1e-33 113.1 0.0 3.2e-32 110.2 0.0 2.0 2 0 0 2 2 2 1 Catechol dioxygenase N terminus Dioxygenase_C PF00775.21 KKK25325.1 - 4.8e-30 104.3 0.1 6.7e-30 103.9 0.1 1.2 1 0 0 1 1 1 1 Dioxygenase CarboxypepD_reg PF13620.6 KKK25325.1 - 0.073 13.3 0.0 0.34 11.2 0.0 2.0 1 1 0 1 1 1 0 Carboxypeptidase regulatory-like domain TFIIA PF03153.13 KKK25326.1 - 6.7e-05 23.1 30.5 6.7e-05 23.1 30.5 2.4 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit Zn_clus PF00172.18 KKK25326.1 - 0.048 13.8 9.7 0.11 12.6 9.7 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain GREB1 PF15782.5 KKK25326.1 - 4.4 4.3 16.8 6.7 3.7 16.8 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Spt20 PF12090.8 KKK25326.1 - 4.7 6.8 42.4 0.098 12.3 34.2 2.4 3 0 0 3 3 3 0 Spt20 family NuA4 PF09340.10 KKK25327.1 - 3.1e-28 97.5 0.9 3.1e-28 97.5 0.9 1.8 2 0 0 2 2 2 1 Histone acetyltransferase subunit NuA4 DUF5320 PF17253.2 KKK25327.1 - 0.02 15.9 2.0 0.053 14.6 1.2 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5320) Ctr PF04145.15 KKK25328.1 - 5.1e-31 108.3 1.0 6e-31 108.1 1.0 1.1 1 0 0 1 1 1 1 Ctr copper transporter family Cupin_8 PF13621.6 KKK25329.1 - 5.8e-15 55.7 0.1 1e-11 45.1 0.0 2.2 1 1 1 2 2 2 2 Cupin-like domain JmjC PF02373.22 KKK25329.1 - 5.3e-10 39.7 0.3 9.9e-09 35.6 0.3 2.4 1 1 0 1 1 1 1 JmjC domain, hydroxylase F-box-like PF12937.7 KKK25329.1 - 7.8e-07 28.9 0.1 1.6e-06 27.9 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KKK25329.1 - 2.3e-05 24.2 0.0 5.5e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 F-box domain DUF3545 PF12065.8 KKK25329.1 - 0.16 12.0 0.2 0.27 11.3 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3545) DEAD PF00270.29 KKK25330.1 - 2.6e-46 157.6 0.6 5.3e-46 156.6 0.6 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KKK25330.1 - 9.6e-32 109.6 0.3 5e-31 107.3 0.1 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KKK25330.1 - 6e-06 26.4 0.0 1e-05 25.6 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 KKK25330.1 - 0.00061 19.6 0.1 0.0013 18.5 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KKK25330.1 - 0.001 19.4 0.5 0.0069 16.7 0.2 2.1 2 1 0 2 2 2 1 AAA domain CMS1 PF14617.6 KKK25330.1 - 0.0041 16.5 0.0 0.009 15.4 0.0 1.5 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit AAA_22 PF13401.6 KKK25330.1 - 0.012 15.9 1.2 0.073 13.3 1.2 2.2 1 1 0 1 1 1 0 AAA domain fragilysinNterm PF16376.5 KKK25330.1 - 0.096 12.4 0.1 0.32 10.7 0.0 1.9 2 0 0 2 2 2 0 N-terminal domain of fragilysin Helicase_RecD PF05127.14 KKK25330.1 - 0.12 12.2 0.0 0.26 11.1 0.0 1.6 1 1 0 1 1 1 0 Helicase PWI PF01480.17 KKK25331.1 - 7.4e-31 106.3 0.1 1.2e-30 105.6 0.1 1.3 1 0 0 1 1 1 1 PWI domain FAA_hydrolase PF01557.18 KKK25332.1 - 1.2e-50 172.3 0.0 1.3e-50 172.1 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Sugar_tr PF00083.24 KKK25333.1 - 1.1e-42 146.5 15.0 2.8e-42 145.1 15.0 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKK25333.1 - 8.8e-18 64.3 34.2 1.2e-17 63.9 30.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3533 PF12051.8 KKK25334.1 - 8e-110 367.3 15.9 2.4e-64 217.6 0.0 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF3533) adh_short PF00106.25 KKK25335.1 - 1.2e-25 90.2 0.0 1.2e-22 80.3 0.0 2.1 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KKK25335.1 - 1.6e-15 57.3 0.1 5.4e-15 55.6 0.0 1.7 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KKK25335.1 - 2.9e-08 33.8 0.0 4.1e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 KKK25335.1 - 0.0019 17.7 0.0 0.0029 17.1 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KKK25335.1 - 0.0072 15.8 0.0 0.02 14.4 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KKK25335.1 - 0.04 13.1 0.0 0.058 12.5 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Shikimate_DH PF01488.20 KKK25335.1 - 0.083 13.0 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF1508 PF07411.12 KKK25335.1 - 0.49 10.3 1.8 3.7 7.5 0.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1508) WD40 PF00400.32 KKK25336.1 - 1.2e-41 139.8 31.2 3.6e-08 33.9 0.6 8.8 7 2 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKK25336.1 - 2.2e-14 53.5 3.6 0.0012 19.0 0.1 4.9 3 1 3 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KKK25336.1 - 5.7e-05 22.0 0.4 0.0037 16.0 0.2 3.2 3 0 0 3 3 3 1 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KKK25336.1 - 0.02 13.8 0.0 5.6 5.8 0.0 3.0 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein SOG2 PF10428.9 KKK25338.1 - 6.3e-112 375.4 7.1 4.6e-111 372.5 0.0 3.0 3 1 0 3 3 3 1 RAM signalling pathway protein LRR_8 PF13855.6 KKK25338.1 - 5e-17 61.4 14.7 6.9e-10 38.5 2.7 3.2 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 KKK25338.1 - 2.3e-09 37.4 6.0 0.00011 22.5 1.3 3.8 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KKK25338.1 - 0.0024 17.8 2.0 16 5.8 0.1 4.5 4 0 0 4 4 4 2 Leucine Rich repeat LRR_1 PF00560.33 KKK25338.1 - 0.011 16.1 4.5 22 6.1 0.1 5.3 5 0 0 5 5 5 0 Leucine Rich Repeat MRP-S25 PF13741.6 KKK25339.1 - 2.7e-83 279.1 9.2 3.1e-83 278.9 9.2 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein S25 MRP-S23 PF10484.9 KKK25339.1 - 0.0044 17.3 1.8 1.1 9.5 0.1 2.5 2 1 0 2 2 2 2 Mitochondrial ribosomal protein S23 hGDE_N PF14699.6 KKK25339.1 - 0.066 13.4 0.7 0.75 10.0 0.0 2.8 3 0 0 3 3 3 0 N-terminal domain from the human glycogen debranching enzyme PPR_2 PF13041.6 KKK25340.1 - 4.3e-09 36.4 0.0 0.012 15.7 0.1 4.1 3 1 1 4 4 4 3 PPR repeat family PPR PF01535.20 KKK25340.1 - 2.3e-07 30.6 0.8 0.096 13.0 0.1 4.3 4 0 0 4 4 4 2 PPR repeat PPR_long PF17177.4 KKK25340.1 - 0.0093 15.4 0.0 0.018 14.4 0.0 1.4 1 0 0 1 1 1 1 Pentacotripeptide-repeat region of PRORP TPR_14 PF13428.6 KKK25340.1 - 0.014 16.2 0.5 6 8.0 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat PPR_3 PF13812.6 KKK25340.1 - 0.033 14.3 0.0 0.16 12.1 0.0 2.1 3 0 0 3 3 3 0 Pentatricopeptide repeat domain SET PF00856.28 KKK25341.1 - 1.7e-18 67.6 0.0 3.2e-18 66.7 0.0 1.5 1 0 0 1 1 1 1 SET domain Methyltransf_PK PF05891.12 KKK25342.1 - 6.2e-69 231.8 0.0 7.1e-69 231.7 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_25 PF13649.6 KKK25342.1 - 1.8e-07 31.8 0.0 2.9e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KKK25342.1 - 5.8e-06 26.9 0.1 8.7e-06 26.3 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KKK25342.1 - 9.1e-06 25.6 0.0 1.3e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KKK25342.1 - 0.00087 20.0 0.0 0.0015 19.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain LEA_2 PF03168.13 KKK25343.1 - 1.8e-08 34.8 4.3 0.044 14.3 0.0 4.9 4 1 0 4 4 4 2 Late embryogenesis abundant protein DUF3712 PF12505.8 KKK25343.1 - 8.1e-07 29.3 0.1 4.2e-06 27.0 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3712) Helicase_C PF00271.31 KKK25344.1 - 1.8e-15 57.3 0.0 8.4e-10 39.0 0.0 3.8 3 1 0 3 3 3 2 Helicase conserved C-terminal domain DEAD PF00270.29 KKK25344.1 - 1.7e-11 44.2 0.0 2.7e-07 30.5 0.1 2.5 1 1 1 2 2 2 2 DEAD/DEAH box helicase RecQ_Zn_bind PF16124.5 KKK25344.1 - 7.9e-07 29.7 0.3 7.9e-07 29.7 0.3 2.4 2 0 0 2 2 2 1 RecQ zinc-binding SR-25 PF10500.9 KKK25344.1 - 0.002 17.8 6.5 0.002 17.8 6.5 1.8 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein Pex14_N PF04695.13 KKK25344.1 - 0.078 13.6 1.9 2.8 8.6 1.1 2.4 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SUIM_assoc PF16619.5 KKK25344.1 - 0.25 11.4 7.0 0.24 11.5 1.3 2.5 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 CCDC24 PF15669.5 KKK25344.1 - 0.55 10.1 4.1 0.18 11.6 1.0 1.7 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 24 family Herpes_capsid PF06112.11 KKK25344.1 - 0.68 10.0 7.4 1.4 8.9 7.4 1.5 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein KH_1 PF00013.29 KKK25345.1 - 1.6e-09 37.4 0.0 2.6e-06 27.1 0.0 2.6 2 0 0 2 2 2 2 KH domain DUF1897 PF09005.10 KKK25345.1 - 0.17 11.4 6.6 0.42 10.1 6.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1897) Med3 PF11593.8 KKK25345.1 - 1.4 8.1 15.3 0.23 10.6 7.5 2.1 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal ALS_ss_C PF10369.9 KKK25346.1 - 3.9e-15 55.8 0.0 7e-14 51.8 0.0 2.3 2 0 0 2 2 2 1 Small subunit of acetolactate synthase ACT PF01842.25 KKK25346.1 - 8.1e-13 47.9 0.1 1.3e-12 47.2 0.1 1.4 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.6 KKK25346.1 - 5.9e-08 32.4 0.0 1.1e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 ACT domain ACT_6 PF13740.6 KKK25346.1 - 0.03 14.3 0.1 6.9 6.7 0.0 2.7 2 0 0 2 2 2 0 ACT domain Limkain-b1 PF11608.8 KKK25346.1 - 0.032 14.3 0.0 0.076 13.1 0.0 1.5 1 0 0 1 1 1 0 Limkain b1 Peptidase_S10 PF00450.22 KKK25347.1 - 2e-71 241.6 0.0 4.2e-70 237.3 0.0 2.4 1 1 0 1 1 1 1 Serine carboxypeptidase Serglycin PF04360.12 KKK25347.1 - 0.11 12.4 1.3 0.19 11.7 0.4 1.8 2 0 0 2 2 2 0 Serglycin Tcp11 PF05794.13 KKK25348.1 - 1.1e-110 370.7 0.5 1.8e-110 370.1 0.5 1.2 1 0 0 1 1 1 1 T-complex protein 11 Ydc2-catalyt PF09159.10 KKK25348.1 - 2.7e-82 276.7 0.0 4.1e-82 276.1 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 SAP PF02037.27 KKK25348.1 - 5.8e-05 22.7 0.0 0.00017 21.3 0.0 1.8 1 0 0 1 1 1 1 SAP domain SUIM_assoc PF16619.5 KKK25348.1 - 0.012 15.6 2.8 0.12 12.5 0.5 2.7 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Pox_A22 PF04848.13 KKK25348.1 - 0.06 13.5 0.0 36 4.4 0.0 3.3 3 0 0 3 3 3 0 Poxvirus A22 protein SelP_N PF04592.14 KKK25349.1 - 0.063 12.7 1.4 0.11 11.9 1.4 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region DUF4587 PF15248.6 KKK25349.1 - 0.22 12.4 1.4 0.5 11.2 1.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4587) CTP_transf_like PF01467.26 KKK25350.1 - 2.4e-05 24.5 0.2 8.7e-05 22.7 0.0 2.0 3 0 0 3 3 3 1 Cytidylyltransferase-like Osmo_CC PF08946.10 KKK25351.1 - 0.029 14.6 0.3 0.047 13.9 0.3 1.3 1 0 0 1 1 1 0 Osmosensory transporter coiled coil Fmp27 PF10344.9 KKK25352.1 - 2.4e-254 846.5 0.0 3.2e-253 842.8 0.0 2.2 2 0 0 2 2 2 1 Mitochondrial protein from FMP27 Apt1 PF10351.9 KKK25352.1 - 1.3e-193 644.3 0.8 1.3e-193 644.3 0.8 3.0 3 0 0 3 3 3 1 Golgi-body localisation protein domain Fmp27_WPPW PF10359.9 KKK25352.1 - 7.8e-173 575.8 4.9 1.5e-172 574.8 4.9 1.5 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.9 KKK25352.1 - 4.2e-59 198.9 0.2 9.2e-59 197.8 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF2405) Fmp27_GFWDK PF10347.9 KKK25352.1 - 8.5e-55 185.1 0.0 2.1e-54 183.9 0.0 1.7 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain Fmp27_SW PF10305.9 KKK25352.1 - 1.7e-32 112.2 0.0 1.3e-30 106.2 0.0 3.3 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain B-block_TFIIIC PF04182.12 KKK25353.1 - 9.6e-22 76.9 0.2 7.1e-21 74.2 0.0 2.4 3 0 0 3 3 3 1 B-block binding subunit of TFIIIC MarR_2 PF12802.7 KKK25353.1 - 0.035 14.0 1.6 0.23 11.4 0.0 3.0 3 0 0 3 3 3 0 MarR family CGI-121 PF08617.10 KKK25357.1 - 7.3e-55 185.5 0.0 8.4e-55 185.3 0.0 1.0 1 0 0 1 1 1 1 Kinase binding protein CGI-121 AAA_assoc PF14363.6 KKK25357.1 - 0.025 14.9 0.2 0.11 12.8 0.1 2.2 1 1 1 2 2 2 0 Domain associated at C-terminal with AAA CAMP_factor PF07373.11 KKK25357.1 - 0.17 11.5 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 CAMP factor (Cfa) Bax1-I PF01027.20 KKK25358.1 - 6e-31 107.9 11.9 9.5e-31 107.2 11.9 1.3 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 VirB8 PF04335.13 KKK25358.1 - 0.25 11.1 0.8 15 5.3 0.1 2.3 2 0 0 2 2 2 0 VirB8 protein Alpha-amylase PF00128.24 KKK25359.1 - 6.5e-55 187.0 0.6 9e-55 186.6 0.6 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.11 KKK25359.1 - 1.4e-31 108.6 0.0 2.6e-31 107.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) RRM_1 PF00076.22 KKK25360.1 - 2.3e-16 59.4 0.0 3.3e-16 58.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KKK25360.1 - 0.0005 19.7 0.0 0.00077 19.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KKK25360.1 - 0.032 14.1 0.0 0.064 13.1 0.0 1.4 1 1 0 1 1 1 0 Occluded RNA-recognition motif RRM_3 PF08777.11 KKK25360.1 - 0.061 13.4 0.0 0.089 12.8 0.0 1.3 1 0 0 1 1 1 0 RNA binding motif Glyco_hydro_76 PF03663.14 KKK25361.1 - 1.8e-20 73.8 5.2 3e-15 56.6 1.1 2.6 2 1 0 2 2 2 2 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 KKK25361.1 - 1.4 8.0 7.4 0.53 9.3 0.1 2.7 3 0 0 3 3 3 0 Glycosyl Hydrolase Family 88 Zn_clus PF00172.18 KKK25363.1 - 0.00018 21.6 7.2 0.0003 20.9 7.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ZapB PF06005.12 KKK25363.1 - 0.0078 16.6 0.5 0.019 15.4 0.5 1.6 1 0 0 1 1 1 1 Cell division protein ZapB DivIC PF04977.15 KKK25363.1 - 0.013 15.2 0.4 0.027 14.2 0.4 1.4 1 0 0 1 1 1 0 Septum formation initiator TMCO5 PF14992.6 KKK25363.1 - 0.027 14.1 0.1 0.043 13.4 0.1 1.2 1 0 0 1 1 1 0 TMCO5 family MbeD_MobD PF04899.12 KKK25363.1 - 0.045 13.9 0.5 0.11 12.7 0.5 1.6 1 0 0 1 1 1 0 MbeD/MobD like HALZ PF02183.18 KKK25363.1 - 0.11 12.7 0.5 0.21 11.8 0.5 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper Cnn_1N PF07989.11 KKK25363.1 - 0.14 12.4 0.2 0.26 11.5 0.2 1.4 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 Macoilin PF09726.9 KKK25363.1 - 0.14 10.7 5.9 0.19 10.2 5.9 1.1 1 0 0 1 1 1 0 Macoilin family CENP-H PF05837.12 KKK25363.1 - 0.24 11.8 0.1 0.24 11.8 0.1 1.9 2 0 0 2 2 2 0 Centromere protein H (CENP-H) XRCC4 PF06632.12 KKK25363.1 - 0.39 9.5 14.9 1.1 8.0 0.4 2.2 2 0 0 2 2 2 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 Spc24 PF08286.11 KKK25363.1 - 0.69 10.2 2.8 0.3 11.4 0.2 1.7 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Csm1_N PF18504.1 KKK25363.1 - 0.78 10.1 2.8 1.6 9.2 2.8 1.4 1 0 0 1 1 1 0 Csm1 N-terminal domain ADIP PF11559.8 KKK25363.1 - 3.9 7.5 7.1 0.18 11.9 0.8 1.8 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Slx4 PF09494.10 KKK25364.1 - 1.4e-24 85.8 0.0 2.7e-24 84.9 0.0 1.5 1 0 0 1 1 1 1 Slx4 endonuclease Tim17 PF02466.19 KKK25365.1 - 0.0031 17.9 1.5 0.0049 17.2 1.4 1.5 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Dr_adhesin PF12393.8 KKK25365.1 - 0.22 11.9 2.1 0.53 10.7 2.1 1.7 1 0 0 1 1 1 0 Dr family adhesin UCR_Fe-S_N PF10399.9 KKK25365.1 - 0.26 10.7 2.2 0.41 10.0 0.1 2.2 2 0 0 2 2 2 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal cNMPbd_u2 PF16643.5 KKK25366.1 - 3.1e-36 125.2 6.6 6.7e-36 124.1 6.6 1.5 1 0 0 1 1 1 1 Unstructured region on cNMP-binding protein cNMP_binding PF00027.29 KKK25366.1 - 1.6e-34 117.8 0.0 4e-21 74.9 0.0 2.7 2 1 0 2 2 2 2 Cyclic nucleotide-binding domain LRR_6 PF13516.6 KKK25366.1 - 1.2e-10 40.6 2.5 0.64 10.2 0.0 8.3 9 0 0 9 9 9 3 Leucine Rich repeat LRR_4 PF12799.7 KKK25366.1 - 3.3e-07 30.5 4.6 0.27 11.7 0.0 7.1 7 1 0 8 8 8 1 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KKK25366.1 - 0.00018 21.3 0.2 0.00061 19.6 0.2 1.9 1 0 0 1 1 1 1 F-box-like LRR_1 PF00560.33 KKK25366.1 - 0.0011 19.2 8.8 68 4.6 0.0 8.1 7 1 1 8 8 8 0 Leucine Rich Repeat F-box PF00646.33 KKK25366.1 - 0.0013 18.5 0.2 0.0013 18.5 0.2 2.4 3 0 0 3 3 3 1 F-box domain Cupin_3 PF05899.12 KKK25366.1 - 0.012 15.3 0.5 1.1 9.0 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF861) SAM_Ste50p PF09235.10 KKK25366.1 - 0.11 12.8 1.5 5.7 7.3 0.3 3.5 3 1 0 3 3 3 0 Ste50p, sterile alpha motif Kinesin PF00225.23 KKK25367.1 - 1.6e-116 388.9 0.0 2.6e-116 388.2 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KKK25367.1 - 2.2e-27 95.8 0.0 6.4e-27 94.3 0.0 1.8 1 0 0 1 1 1 1 Microtubule binding AAA_33 PF13671.6 KKK25367.1 - 0.0029 17.8 1.1 0.021 15.0 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 KKK25367.1 - 0.17 12.2 0.7 1.5 9.1 0.0 2.6 2 0 0 2 2 2 0 AAA ATPase domain Peptidase_S49_N PF08496.10 KKK25367.1 - 0.24 11.5 2.0 13 5.8 0.0 2.6 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Ca_bind_SSO6904 PF18249.1 KKK25369.1 - 0.095 13.1 0.3 19 5.7 0.1 2.6 3 0 0 3 3 3 0 Calcium binding protein SSO6904 PMSR PF01625.21 KKK25370.1 - 5.2e-62 208.6 0.4 6.3e-62 208.3 0.4 1.1 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase Sulfatase PF00884.23 KKK25374.1 - 2.4e-69 234.1 0.0 3e-69 233.8 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 KKK25374.1 - 0.0015 18.2 0.0 0.34 10.4 0.0 2.2 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 KKK25374.1 - 0.0029 16.3 0.0 0.004 15.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF229) DUF4976 PF16347.5 KKK25374.1 - 0.0042 17.3 0.0 0.011 16.0 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4976) Sulfatase_C PF14707.6 KKK25374.1 - 0.016 16.0 0.1 0.25 12.1 0.1 2.3 1 1 0 1 1 1 0 C-terminal region of aryl-sulfatase Sugar_tr PF00083.24 KKK25375.1 - 1.5e-90 304.2 26.9 1.9e-90 303.9 26.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKK25375.1 - 8.6e-17 61.1 15.6 8.6e-17 61.1 15.6 2.2 1 1 0 2 2 2 1 Major Facilitator Superfamily Zn_clus PF00172.18 KKK25376.1 - 7.9e-10 38.7 8.2 1.6e-09 37.8 8.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KKK25376.1 - 0.013 14.5 0.0 0.053 12.6 0.0 2.1 2 1 0 2 2 2 0 Fungal specific transcription factor domain p450 PF00067.22 KKK25377.1 - 1.1e-08 34.2 0.0 1.3e-08 34.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Nuc_deoxyri_tr3 PF11071.8 KKK25377.1 - 0.1 12.6 0.4 6.1 6.9 0.0 2.1 2 0 0 2 2 2 0 Nucleoside 2-deoxyribosyltransferase YtoQ DAO PF01266.24 KKK25378.1 - 1.4e-50 172.8 0.0 2e-50 172.4 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO_C PF16901.5 KKK25378.1 - 6.6e-46 155.3 0.1 1.1e-45 154.5 0.1 1.4 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase FAD_binding_2 PF00890.24 KKK25378.1 - 5.6e-10 38.9 0.1 1.1e-09 37.9 0.1 1.4 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KKK25378.1 - 0.00056 19.2 0.0 0.0019 17.5 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KKK25378.1 - 0.00077 18.9 0.3 0.004 16.6 0.2 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KKK25378.1 - 0.0016 18.6 0.3 0.005 17.0 0.2 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KKK25378.1 - 0.0024 17.2 0.1 0.0049 16.1 0.1 1.4 1 0 0 1 1 1 1 Thi4 family 3HCDH_N PF02737.18 KKK25378.1 - 0.0028 17.5 0.2 0.0051 16.7 0.2 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.22 KKK25378.1 - 0.0047 16.1 0.1 0.034 13.2 0.1 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A HI0933_like PF03486.14 KKK25378.1 - 0.0074 15.0 0.4 0.011 14.4 0.4 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.6 KKK25378.1 - 0.012 14.9 0.0 0.049 12.9 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KKK25378.1 - 0.07 12.4 0.0 0.22 10.7 0.0 1.9 2 1 0 2 2 2 0 FAD binding domain Sacchrp_dh_NADP PF03435.18 KKK25378.1 - 0.086 13.1 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Pyr_redox PF00070.27 KKK25378.1 - 0.097 13.2 0.1 0.32 11.6 0.1 1.9 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase Aa_trans PF01490.18 KKK25379.1 - 1.3e-38 132.8 38.4 1.5e-38 132.6 38.4 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF5510 PF17629.2 KKK25390.1 - 0.0052 16.7 13.4 0.0076 16.2 7.0 2.7 2 1 0 2 2 2 2 Family of unknown function (DUF5510) UPRTase PF14681.6 KKK25390.1 - 0.085 12.3 0.0 0.18 11.2 0.0 1.5 2 0 0 2 2 2 0 Uracil phosphoribosyltransferase DASH_Dad1 PF08649.10 KKK25391.1 - 7.1e-26 90.2 4.6 1.2e-25 89.4 4.6 1.4 1 0 0 1 1 1 1 DASH complex subunit Dad1 DASH_Dad4 PF08650.10 KKK25391.1 - 0.01 15.8 0.2 0.016 15.2 0.2 1.2 1 0 0 1 1 1 0 DASH complex subunit Dad4 Ras PF00071.22 KKK25392.1 - 1.3e-48 164.6 0.0 1.7e-48 164.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KKK25392.1 - 4.9e-21 75.2 0.0 7.9e-21 74.5 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKK25392.1 - 6.1e-05 22.5 0.0 0.0002 20.9 0.0 1.8 1 1 0 1 1 1 1 ADP-ribosylation factor family AAA_7 PF12775.7 KKK25392.1 - 0.018 14.6 0.0 0.032 13.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region SRPRB PF09439.10 KKK25392.1 - 0.039 13.4 0.0 0.062 12.7 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit ERG4_ERG24 PF01222.17 KKK25393.1 - 1.4e-139 465.6 17.8 1.6e-139 465.4 17.8 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Fungal_trans PF04082.18 KKK25394.1 - 2.2e-15 56.4 0.4 6.2e-15 54.9 0.4 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK25394.1 - 1.3e-08 34.8 6.8 2.4e-08 34.0 6.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RasGAP PF00616.19 KKK25395.1 - 9.2e-33 113.7 0.0 5.6e-23 81.7 0.0 2.5 1 1 1 2 2 2 2 GTPase-activator protein for Ras-like GTPase C2 PF00168.30 KKK25395.1 - 6.6e-08 32.8 0.5 4.2e-07 30.2 0.1 2.5 2 1 0 2 2 2 1 C2 domain APG9 PF04109.16 KKK25396.1 - 6.6e-204 678.4 16.9 2.9e-192 640.0 11.9 2.0 1 1 1 2 2 2 2 Autophagy protein Apg9 Glyco_hydro_47 PF01532.20 KKK25397.1 - 1.3e-196 654.0 0.1 1.6e-196 653.7 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Neur_chan_memb PF02932.16 KKK25397.1 - 5.1 7.1 4.9 1.2 9.1 0.5 2.0 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region DUF2013 PF09431.10 KKK25398.1 - 1.6e-52 177.4 1.2 3.4e-52 176.3 1.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2013) MARVEL PF01284.23 KKK25399.1 - 0.00027 21.0 6.2 0.00037 20.5 5.7 1.4 1 1 0 1 1 1 1 Membrane-associating domain PTS_EIIC PF02378.18 KKK25399.1 - 0.0047 16.0 0.2 0.0078 15.3 0.2 1.2 1 0 0 1 1 1 1 Phosphotransferase system, EIIC Sulfatase PF00884.23 KKK25400.1 - 3e-22 79.4 0.4 5.4e-22 78.6 0.4 1.3 1 0 0 1 1 1 1 Sulfatase FMO-like PF00743.19 KKK25400.1 - 6e-21 74.5 0.4 2.1e-20 72.7 0.1 1.9 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KKK25400.1 - 6.2e-18 65.1 0.1 3.1e-17 62.8 0.1 2.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KKK25400.1 - 2e-12 46.9 0.0 1.9e-10 40.5 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KKK25400.1 - 3.8e-09 36.6 0.0 1e-08 35.3 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 KKK25400.1 - 6.4e-09 35.4 1.5 3.3e-07 29.8 0.1 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 KKK25400.1 - 5.4e-07 29.5 0.1 3e-06 27.0 0.1 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Shikimate_DH PF01488.20 KKK25400.1 - 2.3e-05 24.5 0.1 0.32 11.1 0.0 2.7 3 0 0 3 3 3 2 Shikimate / quinate 5-dehydrogenase Phosphodiest PF01663.22 KKK25400.1 - 0.00018 21.2 0.0 0.00036 20.2 0.0 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Pyr_redox PF00070.27 KKK25400.1 - 0.00051 20.5 0.4 0.73 10.4 0.2 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KKK25400.1 - 0.0024 17.0 0.1 0.0038 16.4 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 KKK25400.1 - 0.0034 16.7 0.0 0.0071 15.6 0.0 1.4 1 0 0 1 1 1 1 Thi4 family DUF229 PF02995.17 KKK25400.1 - 0.0063 15.2 0.0 0.01 14.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF229) NAD_binding_9 PF13454.6 KKK25400.1 - 0.0098 15.9 0.6 0.12 12.4 0.0 3.0 3 1 0 3 3 3 1 FAD-NAD(P)-binding NAD_binding_7 PF13241.6 KKK25400.1 - 0.014 15.9 0.0 0.81 10.2 0.1 2.7 2 1 0 2 2 2 0 Putative NAD(P)-binding Metalloenzyme PF01676.18 KKK25400.1 - 0.089 12.1 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Metalloenzyme superfamily HI0933_like PF03486.14 KKK25400.1 - 0.41 9.3 3.1 0.18 10.5 0.4 1.7 2 0 0 2 2 2 0 HI0933-like protein CDH-cyt PF16010.5 KKK25401.1 - 1.5e-63 213.8 3.3 2.6e-63 213.0 3.3 1.4 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase GMC_oxred_N PF00732.19 KKK25401.1 - 4.5e-28 98.5 0.0 2.2e-27 96.2 0.0 2.1 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KKK25401.1 - 5.5e-26 91.8 0.1 1.2e-25 90.7 0.1 1.7 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KKK25401.1 - 1.6e-11 43.9 0.0 5.4e-05 22.5 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KKK25401.1 - 2.4e-06 27.7 0.0 8.7e-06 25.9 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KKK25401.1 - 6.7e-06 25.5 0.0 3.2e-05 23.3 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KKK25401.1 - 0.00016 22.1 0.0 0.29 11.7 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KKK25401.1 - 0.00056 18.7 0.0 0.0011 17.8 0.0 1.4 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.7 KKK25401.1 - 0.001 18.5 0.2 0.19 11.1 0.0 2.5 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KKK25401.1 - 0.0012 18.1 0.1 0.0021 17.4 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 KKK25401.1 - 0.0035 16.4 0.1 0.0055 15.8 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 KKK25401.1 - 0.0065 15.8 0.1 0.06 12.6 0.3 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KKK25401.1 - 0.0068 15.7 0.3 0.014 14.6 0.1 1.6 2 0 0 2 2 2 1 Thi4 family TrkA_N PF02254.18 KKK25401.1 - 0.19 12.0 0.0 0.34 11.2 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain AA_permease PF00324.21 KKK25402.1 - 3.9e-104 348.9 35.7 4.8e-104 348.6 35.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KKK25402.1 - 6.1e-33 114.3 40.1 7e-33 114.1 40.1 1.0 1 0 0 1 1 1 1 Amino acid permease Peptidase_S28 PF05577.12 KKK25403.1 - 8.9e-46 156.6 0.0 3.8e-45 154.5 0.0 1.8 1 1 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S9 PF00326.21 KKK25403.1 - 0.19 11.2 0.0 0.31 10.5 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family Ank_5 PF13857.6 KKK25404.1 - 0.0089 16.3 0.0 0.021 15.2 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 KKK25404.1 - 0.093 13.3 0.0 0.3 11.7 0.0 1.8 1 1 0 1 1 1 0 Ankyrin repeats (many copies) Ank_2 PF12796.7 KKK25404.1 - 0.11 13.0 0.0 0.19 12.3 0.0 1.5 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) RasGEF PF00617.19 KKK25405.1 - 3.7e-40 138.0 0.0 1.2e-39 136.4 0.0 1.8 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 KKK25405.1 - 3.9e-12 46.3 0.1 1e-11 45.0 0.1 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif Transp_cyt_pur PF02133.15 KKK25406.1 - 2.2e-25 89.4 30.6 5.3e-25 88.1 30.6 1.5 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Nramp PF01566.18 KKK25406.1 - 4.8e-06 25.8 18.4 0.00019 20.5 11.6 2.4 2 0 0 2 2 2 2 Natural resistance-associated macrophage protein Fungal_trans PF04082.18 KKK25407.1 - 2.3e-15 56.4 0.0 4.1e-15 55.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK25407.1 - 1.8e-08 34.4 10.1 3.5e-08 33.4 10.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PLDc_2 PF13091.6 KKK25408.1 - 6.8e-21 74.5 0.2 3.1e-11 43.3 0.0 2.4 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 KKK25408.1 - 0.002 18.2 0.1 0.29 11.4 0.1 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif Regulator_TrmB PF11495.8 KKK25408.1 - 0.032 13.4 0.0 0.32 10.1 0.0 2.1 2 0 0 2 2 2 0 Archaeal transcriptional regulator TrmB CBS PF00571.28 KKK25414.1 - 9.2e-35 118.9 5.6 5e-09 36.5 0.0 5.1 5 0 0 5 5 5 4 CBS domain PB1 PF00564.24 KKK25414.1 - 4.9e-07 29.6 0.4 1.5e-06 28.1 0.0 2.1 2 1 0 2 2 2 1 PB1 domain DUF2408 PF10303.9 KKK25415.1 - 1.7e-44 151.7 4.0 4.8e-27 95.2 0.7 5.0 3 2 1 4 4 4 4 Protein of unknown function (DUF2408) Snapin_Pallidin PF14712.6 KKK25415.1 - 0.031 14.7 4.0 0.21 12.1 0.5 3.4 4 0 0 4 4 4 0 Snapin/Pallidin Baculo_PEP_C PF04513.12 KKK25415.1 - 0.048 13.7 1.5 0.13 12.3 0.6 2.2 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Spc7 PF08317.11 KKK25415.1 - 0.048 12.5 0.3 0.075 11.9 0.3 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein CLZ PF16526.5 KKK25415.1 - 0.092 13.1 3.9 0.88 10.0 0.2 3.0 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Prefoldin_2 PF01920.20 KKK25415.1 - 0.12 12.4 0.8 20 5.2 0.0 3.1 1 1 2 3 3 3 0 Prefoldin subunit XhlA PF10779.9 KKK25415.1 - 0.21 11.8 2.2 49 4.2 0.0 3.5 2 1 1 3 3 3 0 Haemolysin XhlA Importin_rep_4 PF18808.1 KKK25416.1 - 6.7e-33 112.8 1.1 6.7e-33 112.8 1.1 3.5 3 0 0 3 3 2 1 Importin repeat Importin_rep_5 PF18816.1 KKK25416.1 - 6.8e-24 83.9 0.5 6.8e-24 83.9 0.5 2.6 2 0 0 2 2 2 1 Importin repeat HEAT_EZ PF13513.6 KKK25416.1 - 9.3e-23 80.3 14.2 8.3e-11 42.2 0.3 9.1 8 2 1 9 9 9 2 HEAT-like repeat HEAT_2 PF13646.6 KKK25416.1 - 1.2e-16 60.8 6.9 0.00015 22.1 0.0 7.9 6 1 1 7 7 7 3 HEAT repeats HEAT PF02985.22 KKK25416.1 - 1.4e-15 56.0 12.7 0.00089 19.3 0.0 11.9 13 0 0 13 13 11 2 HEAT repeat Importin_rep_6 PF18829.1 KKK25416.1 - 1.8e-14 53.8 1.8 6.5e-14 52.0 0.4 2.6 2 0 0 2 2 2 1 Importin repeat 6 Vac14_Fab1_bd PF12755.7 KKK25416.1 - 1.2e-09 38.7 0.2 0.0085 16.7 0.0 6.4 4 2 4 8 8 7 2 Vacuolar 14 Fab1-binding region MMS19_C PF12460.8 KKK25416.1 - 2.3e-09 36.9 2.5 2.7e-06 26.8 0.3 5.2 5 1 1 6 6 6 1 RNAPII transcription regulator C-terminal DUF3385 PF11865.8 KKK25416.1 - 7.7e-09 35.7 0.7 0.052 13.5 0.1 6.2 4 2 1 6 6 6 2 Domain of unknown function (DUF3385) Cnd1 PF12717.7 KKK25416.1 - 2.7e-07 30.8 1.9 0.083 12.9 0.0 5.8 4 4 2 6 6 6 1 non-SMC mitotic condensation complex subunit 1 DRIM PF07539.12 KKK25416.1 - 8.2e-07 27.7 2.4 0.00091 17.6 0.4 3.9 2 2 1 4 4 4 2 Down-regulated in metastasis IFRD PF05004.13 KKK25416.1 - 2.7e-06 26.7 2.0 0.087 11.9 0.2 4.1 2 1 0 2 2 2 2 Interferon-related developmental regulator (IFRD) Arm PF00514.23 KKK25416.1 - 9.4e-06 25.5 3.4 0.016 15.2 0.0 4.8 5 0 0 5 5 4 1 Armadillo/beta-catenin-like repeat CLASP_N PF12348.8 KKK25416.1 - 3.3e-05 23.6 0.2 0.12 12.0 0.1 5.8 6 3 1 7 7 7 1 CLASP N terminal RIX1 PF08167.12 KKK25416.1 - 8.4e-05 22.4 0.1 0.015 15.1 0.1 3.6 2 1 0 2 2 2 1 rRNA processing/ribosome biogenesis IBN_N PF03810.19 KKK25416.1 - 0.00063 19.6 0.3 0.025 14.5 0.0 3.1 2 0 0 2 2 2 1 Importin-beta N-terminal domain RTP1_C1 PF10363.9 KKK25416.1 - 0.0025 18.0 1.9 0.59 10.3 0.6 4.7 4 1 2 6 6 6 1 Required for nuclear transport of RNA pol II C-terminus 1 DNA_alkylation PF08713.11 KKK25416.1 - 0.0074 16.0 0.0 0.07 12.8 0.0 2.7 2 0 0 2 2 2 1 DNA alkylation repair enzyme Adaptin_N PF01602.20 KKK25416.1 - 0.011 14.3 4.4 0.021 13.4 0.6 3.1 4 1 0 4 4 4 0 Adaptin N terminal region Cnd3 PF12719.7 KKK25416.1 - 0.057 12.6 0.1 3.1 6.9 0.0 3.5 2 1 0 3 3 3 0 Nuclear condensing complex subunits, C-term domain TFCD_C PF12612.8 KKK25416.1 - 0.073 12.9 0.1 2.2 8.1 0.0 3.1 2 1 0 2 2 2 0 Tubulin folding cofactor D C terminal DUF4042 PF13251.6 KKK25416.1 - 0.11 12.2 0.1 7.1 6.3 0.0 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4042) Telomere_reg-2 PF10193.9 KKK25416.1 - 0.13 12.7 5.8 0.2 12.1 0.5 3.7 4 0 0 4 4 4 0 Telomere length regulation protein Ribonuc_2-5A PF06479.12 KKK25416.1 - 0.14 12.3 0.0 0.72 10.0 0.1 2.2 2 0 0 2 2 1 0 Ribonuclease 2-5A V-ATPase_H_N PF03224.14 KKK25416.1 - 0.18 11.1 3.4 0.28 10.4 0.2 2.8 3 0 0 3 3 3 0 V-ATPase subunit H TAN PF11640.8 KKK25416.1 - 0.45 10.6 6.1 0.86 9.7 0.2 3.9 3 2 1 4 4 4 0 Telomere-length maintenance and DNA damage repair Ribosomal_60s PF00428.19 KKK25417.1 - 3.2e-13 50.0 19.9 2.4e-12 47.3 19.9 1.9 1 1 0 1 1 1 1 60s Acidic ribosomal protein Ribosomal_S26e PF01283.19 KKK25418.1 - 1.3e-52 176.7 8.1 1.5e-52 176.5 8.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e zf_CopZ PF18423.1 KKK25418.1 - 0.028 14.4 0.5 0.066 13.2 0.0 1.8 2 0 0 2 2 2 0 Zinc binding domain Peptidase_C14 PF00656.22 KKK25419.1 - 2.3e-61 207.9 0.0 2.8e-61 207.6 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Cpn60_TCP1 PF00118.24 KKK25420.1 - 1e-151 505.9 5.7 1.2e-151 505.7 5.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Rep_fac_C PF08542.11 KKK25420.1 - 0.0069 16.8 0.1 0.64 10.5 0.1 2.7 2 0 0 2 2 2 1 Replication factor C C-terminal domain Ribo_biogen_C PF04034.13 KKK25421.1 - 4.5e-33 113.7 0.2 6.4e-33 113.2 0.2 1.2 1 0 0 1 1 1 1 Ribosome biogenesis protein, C-terminal BUD22 PF09073.10 KKK25421.1 - 1.3 8.3 18.1 1.8 7.8 18.1 1.2 1 0 0 1 1 1 0 BUD22 DNA_pol_phi PF04931.13 KKK25421.1 - 7 4.6 22.6 12 3.9 22.6 1.3 1 0 0 1 1 1 0 DNA polymerase phi Gon7 PF08738.10 KKK25422.1 - 0.0073 16.4 3.9 0.53 10.4 1.0 2.4 2 1 0 2 2 2 2 Gon7 family LRR_4 PF12799.7 KKK25423.1 - 2.9e-05 24.3 0.6 1.6 9.2 0.5 3.9 2 1 2 4 4 4 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KKK25423.1 - 0.002 18.1 0.6 0.51 10.5 0.0 3.3 3 0 0 3 3 3 2 Leucine Rich repeat Sugar_tr PF00083.24 KKK25424.1 - 9.1e-27 94.0 8.6 1e-26 93.8 8.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter PRK PF00485.18 KKK25425.1 - 1.8e-52 177.9 0.1 7.9e-52 175.9 0.1 1.9 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family UPRTase PF14681.6 KKK25425.1 - 1.9e-41 141.8 0.0 4.9e-41 140.5 0.0 1.6 2 0 0 2 2 2 1 Uracil phosphoribosyltransferase AAA_18 PF13238.6 KKK25425.1 - 4.3e-07 30.5 0.0 1.2e-06 29.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain CPT PF07931.12 KKK25425.1 - 3.6e-05 23.7 0.0 7.9e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_17 PF13207.6 KKK25425.1 - 0.0019 18.6 0.2 4.4 7.7 0.0 3.0 4 0 0 4 4 4 2 AAA domain Zeta_toxin PF06414.12 KKK25425.1 - 0.015 14.5 0.0 0.032 13.5 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_33 PF13671.6 KKK25425.1 - 0.016 15.4 0.0 0.031 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KKK25425.1 - 0.071 13.5 0.0 0.19 12.1 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain Cytidylate_kin PF02224.18 KKK25425.1 - 0.11 12.2 0.1 1.6 8.4 0.0 2.2 2 0 0 2 2 2 0 Cytidylate kinase NB-ARC PF00931.22 KKK25425.1 - 0.13 11.4 0.0 0.26 10.5 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_5 PF07728.14 KKK25425.1 - 0.16 11.9 0.0 0.82 9.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) CbiA PF01656.23 KKK25425.1 - 0.17 11.9 0.0 0.51 10.4 0.0 1.8 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain APS_kinase PF01583.20 KKK25425.1 - 0.17 11.7 0.1 1.1 9.1 0.1 2.1 2 0 0 2 2 2 0 Adenylylsulphate kinase ABC_tran PF00005.27 KKK25425.1 - 0.24 11.9 0.8 1.8 9.1 0.2 2.2 2 0 0 2 2 2 0 ABC transporter CLTH PF10607.9 KKK25426.1 - 1.6e-29 102.7 0.0 2e-29 102.4 0.0 1.1 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 KKK25426.1 - 6.5e-08 32.3 0.0 1.2e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 LisH NUC153 PF08159.12 KKK25427.1 - 3.2e-15 55.6 5.7 4.5e-14 52.0 0.6 3.6 3 0 0 3 3 3 2 NUC153 domain FNIP_N PF14636.6 KKK25428.1 - 4.7e-11 43.9 19.9 1.3e-10 42.5 0.0 5.2 4 2 1 5 5 5 3 Folliculin-interacting protein N-terminus LPD22 PF18834.1 KKK25428.1 - 0.0094 16.1 0.4 0.031 14.5 0.4 1.9 1 0 0 1 1 1 1 Large polyvalent protein associated domain 22 Glyco_hydro_31 PF01055.26 KKK25429.1 - 1.2e-103 347.7 1.6 2.5e-103 346.7 1.6 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 KKK25429.1 - 2.3e-18 66.2 0.8 1.7e-17 63.5 0.2 2.7 3 0 0 3 3 3 1 Galactose mutarotase-like Phage_X PF05155.15 KKK25429.1 - 0.17 12.3 0.0 0.47 10.9 0.0 1.7 1 0 0 1 1 1 0 Phage X family 60KD_IMP PF02096.20 KKK25430.1 - 3.3e-08 33.6 0.9 5.4e-06 26.4 0.1 2.1 2 0 0 2 2 2 2 60Kd inner membrane protein zf-C2H2 PF00096.26 KKK25431.1 - 9.7e-13 47.8 13.7 4e-06 27.0 4.4 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KKK25431.1 - 4.1e-12 45.9 9.0 1.9e-07 31.2 0.2 3.6 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 KKK25431.1 - 6e-08 32.9 12.4 0.0018 19.0 3.1 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KKK25431.1 - 2.4e-07 30.6 7.5 0.00076 19.4 1.0 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.7 KKK25431.1 - 0.00015 22.0 1.6 0.036 14.5 0.5 3.1 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KKK25431.1 - 0.0019 18.4 8.6 0.17 12.2 0.3 3.6 4 0 0 4 4 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 KKK25431.1 - 0.037 13.8 5.9 1.7 8.5 1.3 3.3 3 0 0 3 3 3 0 zinc-finger C2H2-type Zn_ribbon_recom PF13408.6 KKK25431.1 - 0.13 12.8 0.9 0.28 11.7 0.9 1.5 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain zf-Di19 PF05605.12 KKK25431.1 - 0.19 12.0 2.1 0.39 11.1 2.1 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2HE PF16278.5 KKK25431.1 - 0.31 11.5 3.1 27 5.3 3.1 2.5 1 1 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger zf-CCHC_2 PF13696.6 KKK25431.1 - 0.53 10.2 2.1 6.3 6.7 0.3 2.5 2 0 0 2 2 2 0 Zinc knuckle LIM PF00412.22 KKK25431.1 - 1.1 9.5 4.3 28 5.0 0.4 2.4 1 1 1 2 2 2 0 LIM domain FYVE PF01363.21 KKK25431.1 - 2 8.6 4.6 3.7 7.7 4.6 1.5 1 0 0 1 1 1 0 FYVE zinc finger C5HCH PF17982.1 KKK25431.1 - 2.4 8.4 6.8 8.4 6.6 0.6 2.6 1 1 1 2 2 2 0 NSD Cys-His rich domain ALG11_N PF15924.5 KKK25432.1 - 1e-82 277.2 0.0 1.5e-82 276.7 0.0 1.2 1 0 0 1 1 1 1 ALG11 mannosyltransferase N-terminus Glycos_transf_1 PF00534.20 KKK25432.1 - 1.2e-15 57.5 0.0 2.1e-15 56.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KKK25432.1 - 2.6e-08 34.4 0.0 6.4e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KKK25432.1 - 0.00016 21.8 0.0 0.00046 20.2 0.0 1.9 2 1 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 KKK25432.1 - 0.0097 16.4 0.0 0.024 15.1 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain MRI PF15325.6 KKK25432.1 - 0.028 15.5 1.4 0.056 14.5 1.4 1.4 1 0 0 1 1 1 0 Modulator of retrovirus infection Glyco_hydro_53 PF07745.13 KKK25433.1 - 8.8e-59 199.2 0.0 9.8e-59 199.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 53 Sirohm_synth_C PF14823.6 KKK25436.1 - 6.6e-33 112.2 0.0 1e-32 111.6 0.0 1.3 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal NAD_binding_7 PF13241.6 KKK25436.1 - 2e-31 108.5 0.0 3.1e-31 107.9 0.0 1.3 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_M PF14824.6 KKK25436.1 - 9.9e-15 53.7 0.1 9.9e-15 53.7 0.1 1.6 2 0 0 2 2 2 1 Sirohaem biosynthesis protein central Pyr_redox_3 PF13738.6 KKK25436.1 - 0.016 14.5 0.1 0.023 13.9 0.1 1.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 KKK25436.1 - 0.02 15.1 0.1 0.045 14.0 0.1 1.6 1 1 0 1 1 1 0 TrkA-N domain LSDAT_prok PF18171.1 KKK25436.1 - 0.056 12.7 0.1 0.083 12.1 0.1 1.2 1 0 0 1 1 1 0 SLOG in TRPM, prokaryote Shikimate_DH PF01488.20 KKK25436.1 - 0.079 13.0 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF4061 PF13270.6 KKK25436.1 - 0.12 12.7 0.0 0.22 11.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4061) Sec7 PF01369.20 KKK25437.1 - 5.7e-71 238.0 1.2 1.6e-70 236.5 1.2 1.8 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 KKK25437.1 - 2e-43 148.0 12.8 4.4e-43 146.9 8.2 3.0 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 KKK25437.1 - 7e-35 118.7 10.0 1e-32 111.8 0.1 5.6 5 0 0 5 5 5 2 Domain of unknown function (DUF1981) DCB PF16213.5 KKK25437.1 - 2.5e-16 59.8 9.7 2.9e-16 59.6 0.4 3.8 4 0 0 4 4 4 1 Dimerisation and cyclophilin-binding domain of Mon2 DUF4168 PF13767.6 KKK25437.1 - 0.56 11.4 3.4 31 5.8 0.0 4.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4168) Ldh_1_C PF02866.18 KKK25438.1 - 2.4e-46 157.7 0.0 6.9e-46 156.2 0.0 1.8 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 KKK25438.1 - 2.1e-44 151.0 0.0 2e-43 147.8 0.0 2.0 2 0 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 KKK25438.1 - 0.00072 18.6 0.0 0.001 18.2 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family THF_DHG_CYH_C PF02882.19 KKK25438.1 - 0.053 12.8 0.0 0.51 9.7 0.0 2.5 2 1 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Semialdhyde_dh PF01118.24 KKK25438.1 - 0.066 13.6 0.2 0.77 10.2 0.0 2.6 2 1 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain 2-oxoacid_dh PF00198.23 KKK25440.1 - 4.5e-77 258.6 0.1 5.9e-77 258.2 0.1 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 KKK25440.1 - 5.7e-17 61.3 2.5 1.2e-16 60.3 0.4 2.4 2 0 0 2 2 2 1 Biotin-requiring enzyme E3_binding PF02817.17 KKK25440.1 - 6.2e-13 48.8 0.6 1.9e-12 47.3 0.6 1.9 1 0 0 1 1 1 1 e3 binding domain SopE_GEF PF07487.13 KKK25440.1 - 0.057 13.5 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 SopE GEF domain DUF5353 PF17304.2 KKK25441.1 - 3.7e-26 90.7 4.3 6.1e-26 90.0 4.3 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5353) V-SNARE_C PF12352.8 KKK25441.1 - 5.6e-16 58.6 0.4 1.5e-15 57.2 0.4 1.8 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 KKK25441.1 - 0.00024 21.0 0.0 0.0017 18.2 0.0 2.3 2 0 0 2 2 2 1 Sec20 BAR_2 PF10455.9 KKK25441.1 - 0.011 14.9 0.0 0.011 14.9 0.0 1.6 2 0 0 2 2 2 0 Bin/amphiphysin/Rvs domain for vesicular trafficking Sigma70_r4 PF04545.16 KKK25441.1 - 0.032 13.8 0.3 0.07 12.7 0.3 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 She9_MDM33 PF05546.11 KKK25441.1 - 0.055 13.3 0.3 0.055 13.3 0.3 1.9 2 0 0 2 2 2 0 She9 / Mdm33 family Goodbye PF17109.5 KKK25441.1 - 0.087 13.3 3.6 0.25 11.8 1.0 2.5 2 0 0 2 2 2 0 fungal STAND N-terminal Goodbye domain TPR_MLP1_2 PF07926.12 KKK25441.1 - 1.1 9.4 12.4 0.45 10.6 2.3 3.0 3 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein CCDC-167 PF15188.6 KKK25441.1 - 4 7.8 5.6 3.5 8.0 0.6 2.4 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 PP28 PF10252.9 KKK25441.1 - 8.3 6.9 13.0 0.23 11.9 2.8 2.8 2 1 0 2 2 2 0 Casein kinase substrate phosphoprotein PP28 Pribosyltran_N PF13793.6 KKK25443.1 - 6.1e-45 151.9 0.1 8.1e-42 141.8 0.0 2.4 2 0 0 2 2 2 2 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 KKK25443.1 - 1.5e-35 122.9 0.1 1.1e-30 107.0 0.1 2.2 2 0 0 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 KKK25443.1 - 1.3e-09 37.8 0.0 1.3e-06 28.1 0.0 2.4 2 0 0 2 2 2 2 Phosphoribosyl transferase domain DUF1115 PF06544.12 KKK25444.1 - 1.1e-10 41.8 0.0 1.8e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) COX6B PF02297.17 KKK25445.1 - 1.5e-10 41.2 0.3 1.7e-10 41.0 0.3 1.0 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb CX9C PF16860.5 KKK25445.1 - 0.042 13.9 0.1 0.064 13.3 0.1 1.3 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, CHCH PF06747.13 KKK25445.1 - 0.1 12.7 0.1 0.17 12.0 0.1 1.4 1 1 0 1 1 1 0 CHCH domain tRNA-synt_2 PF00152.20 KKK25446.1 - 4.7e-89 298.6 0.0 7.3e-89 297.9 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KKK25446.1 - 1e-05 25.4 0.0 1.8e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain FANCI_S2 PF14676.6 KKK25447.1 - 0.076 13.3 0.0 0.085 13.2 0.0 1.1 1 0 0 1 1 1 0 FANCI solenoid 2 Ecl1 PF12855.7 KKK25448.1 - 2.6e-48 165.4 14.1 2.6e-48 165.4 14.1 1.8 2 0 0 2 2 2 1 ECL1/2/3 zinc binding proteins zf-MYND PF01753.18 KKK25448.1 - 0.0088 16.1 0.4 0.018 15.1 0.4 1.4 1 0 0 1 1 1 1 MYND finger zf-FLZ PF04570.14 KKK25448.1 - 0.027 13.9 3.9 0.079 12.4 3.9 1.7 1 1 0 1 1 1 0 zinc-finger of the FCS-type, C2-C2 PLATZ PF04640.14 KKK25448.1 - 0.14 12.7 0.2 0.27 11.9 0.2 1.4 1 0 0 1 1 1 0 PLATZ transcription factor DUF2256 PF10013.9 KKK25448.1 - 0.57 10.4 4.5 1.2 9.4 0.6 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) Mannitol_dh_C PF08125.13 KKK25456.1 - 1.4e-41 142.6 0.0 2.3e-41 141.9 0.0 1.3 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.23 KKK25456.1 - 2.6e-15 56.9 0.2 1.7e-14 54.3 0.0 2.2 2 0 0 2 2 2 1 Mannitol dehydrogenase Rossmann domain ECH_1 PF00378.20 KKK25457.1 - 7.5e-18 64.7 0.8 9.5e-18 64.4 0.8 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase WPP PF13943.6 KKK25457.1 - 0.094 13.1 0.1 0.14 12.6 0.1 1.4 1 1 0 1 1 1 0 WPP domain DUF1731 PF08338.11 KKK25457.1 - 0.11 12.3 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1731) Ribosomal_S17e PF00833.18 KKK25458.1 - 3.3e-60 201.4 1.0 4.1e-60 201.1 1.0 1.1 1 0 0 1 1 1 1 Ribosomal S17 Mit_ribos_Mrp51 PF11709.8 KKK25459.1 - 1.3e-112 377.0 0.1 1.7e-112 376.6 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit Epimerase PF01370.21 KKK25459.1 - 4e-16 59.2 0.0 6.8e-16 58.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KKK25459.1 - 1.4e-09 37.4 0.0 2.2e-09 36.7 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KKK25459.1 - 4.4e-09 36.2 0.0 7.3e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 KKK25459.1 - 1.9e-06 27.2 0.0 7.8e-06 25.2 0.0 1.8 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 KKK25459.1 - 0.00012 22.1 0.0 0.00022 21.2 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 KKK25459.1 - 0.0041 16.6 0.0 0.007 15.8 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KKK25459.1 - 0.036 14.0 0.0 0.068 13.1 0.0 1.4 1 0 0 1 1 1 0 KR domain UPF0184 PF03670.13 KKK25459.1 - 0.041 14.3 0.6 0.098 13.1 0.6 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0184) RPAP2_Rtr1 PF04181.13 KKK25460.1 - 3.7e-22 78.4 0.0 6.3e-22 77.7 0.0 1.4 1 0 0 1 1 1 1 Rtr1/RPAP2 family CaM_binding PF07839.11 KKK25460.1 - 0.16 12.7 0.0 0.3 11.8 0.0 1.4 1 0 0 1 1 1 0 Plant calmodulin-binding domain ThiF PF00899.21 KKK25462.1 - 9.2e-74 247.9 0.0 1.3e-73 247.4 0.0 1.1 1 0 0 1 1 1 1 ThiF family UAE_UbL PF14732.6 KKK25462.1 - 8.8e-23 80.7 0.1 2.9e-22 79.0 0.1 1.9 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain UBA_e1_thiolCys PF10585.9 KKK25462.1 - 3.8e-11 43.4 2.6 1e-06 28.9 0.1 2.8 1 1 1 2 2 2 2 Ubiquitin-activating enzyme active site NAD_binding_7 PF13241.6 KKK25462.1 - 0.0003 21.2 0.3 0.0014 19.0 0.0 2.3 3 0 0 3 3 3 1 Putative NAD(P)-binding Shikimate_DH PF01488.20 KKK25462.1 - 0.021 14.9 0.0 0.15 12.1 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Polbeta PF18765.1 KKK25462.1 - 0.026 14.6 3.8 1.9 8.6 1.2 2.9 2 1 0 2 2 2 0 Polymerase beta, Nucleotidyltransferase Pyr_redox PF00070.27 KKK25462.1 - 0.12 13.0 0.1 3.3 8.3 0.0 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Seryl_tRNA_N PF02403.22 KKK25462.1 - 2.3 8.5 5.4 1.8 8.8 0.0 3.0 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Q_salvage PF10343.9 KKK25463.1 - 1.4e-137 457.9 0.0 1.8e-137 457.6 0.0 1.1 1 0 0 1 1 1 1 Potential Queuosine, Q, salvage protein family DUF1563 PF07599.11 KKK25463.1 - 0.22 11.6 0.8 0.41 10.8 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1563) adh_short_C2 PF13561.6 KKK25464.1 - 4.8e-32 111.4 0.1 8.1e-29 100.8 0.0 2.4 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase tRNA_int_end_N2 PF12928.7 KKK25464.1 - 5.6e-31 106.5 0.0 1e-30 105.7 0.0 1.5 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term adh_short PF00106.25 KKK25464.1 - 6.1e-31 107.4 0.0 1.8e-22 79.8 0.0 2.5 2 1 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 KKK25464.1 - 6.1e-08 32.8 0.1 5.8e-07 29.6 0.1 2.4 2 1 0 2 2 2 1 KR domain tRNA_int_endo_N PF02778.14 KKK25464.1 - 0.038 13.7 0.0 0.079 12.6 0.0 1.4 1 0 0 1 1 1 0 tRNA intron endonuclease, N-terminal domain Epimerase PF01370.21 KKK25464.1 - 0.17 11.3 0.1 4.5 6.6 0.2 3.0 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family APH PF01636.23 KKK25465.1 - 1.4e-13 51.3 0.0 3.2e-13 50.2 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KKK25465.1 - 0.00083 18.8 0.0 0.23 10.8 0.0 2.6 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1679 PF07914.11 KKK25465.1 - 0.0044 15.9 0.0 0.0098 14.8 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1679) Choline_kinase PF01633.20 KKK25465.1 - 0.0059 16.2 0.0 0.014 15.0 0.0 1.6 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.25 KKK25465.1 - 0.1 11.9 0.0 4.5 6.6 0.0 2.3 2 0 0 2 2 2 0 Protein kinase domain SBDS_C PF09377.10 KKK25474.1 - 5e-44 149.0 0.0 8.2e-44 148.3 0.0 1.4 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.18 KKK25474.1 - 9.4e-30 102.5 0.0 1.8e-29 101.6 0.0 1.5 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein Carbpep_Y_N PF05388.11 KKK25475.1 - 3.9e-11 43.6 0.1 7.2e-11 42.7 0.1 1.5 1 1 0 1 1 1 1 Carboxypeptidase Y pro-peptide Peptidase_S10 PF00450.22 KKK25475.1 - 2.6e-09 37.0 0.0 3.3e-09 36.7 0.0 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase Peptidase_S10 PF00450.22 KKK25476.1 - 3.9e-96 323.0 0.0 4.4e-96 322.8 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase zf-TRAF_2 PF15965.5 KKK25476.1 - 0.14 12.6 0.7 0.24 11.9 0.7 1.3 1 0 0 1 1 1 0 TRAF-like zinc-finger Ribosomal_S13 PF00416.22 KKK25477.1 - 4.9e-37 127.2 0.9 5.6e-37 127.0 0.9 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 PALP PF00291.25 KKK25478.1 - 6.5e-45 153.8 1.7 7.6e-45 153.6 1.7 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DC_STAMP PF07782.13 KKK25483.1 - 0.11 12.4 0.0 0.11 12.4 0.0 1.1 1 0 0 1 1 1 0 DC-STAMP-like protein FeoB_associated PF12669.7 KKK25483.1 - 0.4 11.1 1.6 0.6 10.6 1.6 1.4 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein Baculo_E56 PF04639.12 KKK25483.1 - 1.4 8.2 3.9 1.6 7.9 3.9 1.1 1 0 0 1 1 1 0 Baculoviral E56 protein, specific to ODV envelope DUF3984 PF13136.6 KKK25521.1 - 9.7e-101 337.5 27.2 9.7e-101 337.5 27.2 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3984) Nop14 PF04147.12 KKK25521.1 - 0.19 9.9 9.4 0.29 9.3 9.4 1.2 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 KKK25521.1 - 1.3 7.1 16.0 1.8 6.6 16.0 1.1 1 0 0 1 1 1 0 DNA polymerase phi OTCace_N PF02729.21 KKK25522.1 - 2.2e-44 151.1 0.0 4e-44 150.2 0.0 1.4 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.24 KKK25522.1 - 1.1e-43 149.1 0.0 1.7e-43 148.4 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain SNARE PF05739.19 KKK25523.1 - 1.9e-14 53.4 0.8 3.5e-14 52.5 0.8 1.5 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.25 KKK25523.1 - 0.0036 17.0 9.7 0.0036 17.0 9.7 1.9 2 1 0 2 2 2 1 Syntaxin Citrate_synt PF00285.21 KKK25523.1 - 0.067 12.2 0.1 0.11 11.5 0.1 1.3 1 0 0 1 1 1 0 Citrate synthase, C-terminal domain HlyD_D4 PF16572.5 KKK25523.1 - 0.068 13.0 0.1 0.32 10.9 0.0 2.1 2 0 0 2 2 2 0 Long alpha hairpin domain of cation efflux system protein, CusB GCP_C_terminal PF04130.13 KKK25523.1 - 0.083 12.3 2.1 0.1 12.0 1.4 1.5 1 1 0 1 1 1 0 Gamma tubulin complex component C-terminal DASH_Dad4 PF08650.10 KKK25523.1 - 0.26 11.3 0.9 3.3 7.7 0.1 2.4 2 0 0 2 2 2 0 DASH complex subunit Dad4 MCPsignal PF00015.21 KKK25523.1 - 0.4 10.5 7.0 0.1 12.4 0.4 2.6 3 0 0 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain SlyX PF04102.12 KKK25523.1 - 0.63 10.7 8.1 2.9 8.6 0.2 3.7 3 1 0 3 3 3 0 SlyX DUF948 PF06103.11 KKK25523.1 - 0.88 9.9 4.9 48 4.3 0.0 3.3 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) MukF_M PF17192.4 KKK25523.1 - 1.9 8.2 6.8 2.5 7.8 0.4 2.3 2 0 0 2 2 2 0 MukF middle domain Lebercilin PF15619.6 KKK25523.1 - 2 8.0 6.9 7.8 6.1 0.8 2.3 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease BBP1_C PF15272.6 KKK25523.1 - 2.8 7.7 6.6 10 5.9 0.6 2.7 1 1 1 3 3 3 0 Spindle pole body component BBP1, C-terminal CTD_bind PF04818.13 KKK25524.1 - 1.2e-17 64.5 0.1 2.9e-17 63.2 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase II-binding domain. DnaG_DnaB_bind PF08278.11 KKK25524.1 - 0.15 12.6 3.2 0.34 11.5 0.3 2.3 2 0 0 2 2 2 0 DNA primase DnaG DnaB-binding Haspin_kinase PF12330.8 KKK25525.1 - 2.6e-40 138.5 0.0 3.7e-40 138.0 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain ABC_membrane PF00664.23 KKK25526.1 - 3.6e-49 167.9 8.7 4.6e-49 167.5 8.7 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 KKK25526.1 - 3.3e-35 121.6 0.0 8.2e-35 120.3 0.0 1.7 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KKK25526.1 - 0.00047 19.6 0.8 0.027 13.9 0.8 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KKK25526.1 - 0.013 15.3 0.0 0.035 13.8 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 KKK25526.1 - 0.02 15.3 1.4 0.052 13.9 0.1 2.3 2 1 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 KKK25526.1 - 0.02 15.1 0.1 0.12 12.7 0.1 2.1 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KKK25526.1 - 0.027 14.2 0.0 0.076 12.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 KKK25526.1 - 0.052 14.0 0.0 0.27 11.7 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 KKK25526.1 - 0.054 13.2 0.1 0.71 9.6 0.0 2.5 2 1 1 3 3 3 0 IstB-like ATP binding protein SbcCD_C PF13558.6 KKK25526.1 - 0.07 13.4 0.8 1.3 9.3 0.8 2.8 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit ABC_ATPase PF09818.9 KKK25526.1 - 0.084 11.7 0.3 0.34 9.7 0.1 1.8 2 0 0 2 2 2 0 Predicted ATPase of the ABC class DEAD PF00270.29 KKK25526.1 - 0.16 11.7 0.0 1.8 8.3 0.1 2.4 2 1 0 2 2 2 0 DEAD/DEAH box helicase Nucleoside_tran PF01733.18 KKK25527.1 - 4.8e-47 160.8 20.7 5.2e-47 160.7 13.7 2.5 2 1 0 2 2 2 1 Nucleoside transporter p53-inducible11 PF14936.6 KKK25527.1 - 0.21 11.6 4.2 0.078 13.0 0.8 2.0 2 0 0 2 2 2 0 Tumour protein p53-inducible protein 11 Clathrin_lg_ch PF01086.17 KKK25528.1 - 2.9e-74 250.0 2.2 3.2e-74 249.8 2.2 1.0 1 0 0 1 1 1 1 Clathrin light chain DUF5067 PF16729.5 KKK25528.1 - 0.056 13.4 1.1 0.48 10.3 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5067) DUF3332 PF11810.8 KKK25528.1 - 0.23 11.1 0.4 0.32 10.6 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3332) CDC37_N PF03234.14 KKK25529.1 - 2.2e-48 164.4 4.1 2.2e-48 164.4 4.1 3.1 3 1 0 3 3 3 1 Cdc37 N terminal kinase binding CDC37_M PF08565.11 KKK25529.1 - 6.6e-43 145.4 0.9 1.7e-42 144.1 0.2 2.0 2 0 0 2 2 2 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.10 KKK25529.1 - 8.1e-34 115.7 3.8 8.1e-34 115.7 3.8 2.0 2 0 0 2 2 2 1 Cdc37 C terminal domain DUF4007 PF13182.6 KKK25529.1 - 0.022 13.9 0.0 0.053 12.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4007) Cytochrom_B562 PF07361.11 KKK25529.1 - 0.34 11.6 5.7 0.78 10.4 0.1 3.1 3 1 0 3 3 3 0 Cytochrome b562 Ribosomal_L12 PF00542.19 KKK25529.1 - 0.66 10.4 5.3 0.51 10.7 2.4 2.4 2 1 0 2 2 2 0 Ribosomal protein L7/L12 C-terminal domain EF-hand_1 PF00036.32 KKK25530.1 - 1.3e-41 137.0 11.6 7.8e-10 37.6 0.9 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KKK25530.1 - 3.6e-36 123.4 5.3 3.9e-19 68.9 2.2 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 KKK25530.1 - 1.9e-34 117.3 11.5 2.4e-15 56.1 0.6 4.0 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 KKK25530.1 - 3.8e-30 101.2 8.5 7.1e-09 34.9 0.1 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 KKK25530.1 - 6.8e-26 88.6 9.8 4.7e-06 25.9 0.1 4.2 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 KKK25530.1 - 1.4e-16 60.5 0.4 2.3e-09 37.4 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 KKK25530.1 - 6.8e-10 38.8 1.6 0.00078 19.4 0.3 2.1 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 KKK25530.1 - 5.9e-09 36.2 0.2 0.0016 18.7 0.1 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.13 KKK25530.1 - 1e-06 28.6 0.1 0.008 16.2 0.0 3.0 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.10 KKK25530.1 - 6.4e-06 26.2 1.6 2.3e-05 24.4 0.2 2.3 2 1 0 2 2 2 1 Ca2+ insensitive EF hand EF-hand_11 PF08976.11 KKK25530.1 - 9.4e-05 23.2 0.2 0.0025 18.6 0.1 2.0 1 1 1 2 2 2 1 EF-hand domain TerB PF05099.13 KKK25530.1 - 0.00013 21.9 0.3 0.35 10.8 0.0 2.2 1 1 1 2 2 2 2 Tellurite resistance protein TerB Caleosin PF05042.13 KKK25530.1 - 0.00059 19.8 1.6 0.52 10.2 0.0 3.5 1 1 3 4 4 4 1 Caleosin related protein RNA_pol_Rpb4 PF03874.16 KKK25530.1 - 0.00062 20.1 0.7 0.66 10.3 0.1 2.6 2 1 1 3 3 3 2 RNA polymerase Rpb4 Dockerin_1 PF00404.18 KKK25530.1 - 0.0053 16.9 7.0 0.38 11.0 0.8 2.9 1 1 2 3 3 3 2 Dockerin type I domain DUF5580 PF17743.1 KKK25530.1 - 0.0057 15.3 0.0 0.0058 15.2 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5580) SurA_N_2 PF13623.6 KKK25530.1 - 0.0084 16.0 0.7 0.32 10.9 0.1 2.2 1 1 1 2 2 2 1 SurA N-terminal domain EF-hand_14 PF17959.1 KKK25530.1 - 0.012 16.0 0.5 6.2 7.2 0.1 2.4 1 1 1 2 2 2 0 EF-hand domain Poly_export PF02563.16 KKK25530.1 - 0.023 14.9 0.0 0.18 12.0 0.0 2.5 2 1 0 2 2 2 0 Polysaccharide biosynthesis/export protein RuvA_C PF07499.13 KKK25530.1 - 0.058 13.9 0.1 8.5 6.9 0.0 3.0 3 0 0 3 3 3 0 RuvA, C-terminal domain dCache_2 PF08269.11 KKK25530.1 - 0.061 12.5 0.1 1 8.5 0.1 2.1 1 1 1 2 2 2 0 Cache domain MotA_activ PF09114.10 KKK25530.1 - 0.061 13.5 0.3 0.91 9.7 0.0 2.3 1 1 0 2 2 2 0 Transcription factor MotA, activation domain DUF4497 PF14924.6 KKK25530.1 - 0.092 13.2 0.0 8.7 6.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4497) RloB PF13707.6 KKK25530.1 - 0.11 12.7 1.3 0.72 10.0 0.2 2.1 1 1 1 2 2 2 0 RloB-like protein DUF5132 PF17195.4 KKK25530.1 - 0.16 12.1 0.5 21 5.3 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF5132) Med20 PF08612.11 KKK25531.1 - 5.1e-95 317.1 0.0 5.8e-95 316.9 0.0 1.0 1 0 0 1 1 1 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex Glyco_hydro_47 PF01532.20 KKK25532.1 - 4.4e-188 625.8 0.0 5.1e-188 625.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Glyco_hydro_127 PF07944.12 KKK25532.1 - 0.027 13.0 0.0 2 6.8 0.0 2.1 2 0 0 2 2 2 0 Beta-L-arabinofuranosidase, GH127 Phage_holin_2_1 PF04971.12 KKK25533.1 - 0.015 15.2 0.3 0.015 15.2 0.3 2.5 4 0 0 4 4 4 0 Bacteriophage P21 holin S FA_desaturase PF00487.24 KKK25533.1 - 5.9 6.7 9.3 3 7.6 4.7 2.1 2 0 0 2 2 2 0 Fatty acid desaturase AA_permease_2 PF13520.6 KKK25534.1 - 1.1e-54 185.9 51.7 1.5e-54 185.5 51.7 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KKK25534.1 - 1.3e-22 80.1 46.8 1.7e-22 79.7 46.8 1.0 1 0 0 1 1 1 1 Amino acid permease APH PF01636.23 KKK25535.1 - 1.4e-12 48.1 0.0 1.3e-11 44.9 0.0 2.4 2 1 0 2 2 2 1 Phosphotransferase enzyme family DUF5041 PF16444.5 KKK25535.1 - 0.038 14.3 0.0 0.063 13.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5041) Alpha-amylase PF00128.24 KKK25536.1 - 1.2e-65 222.3 1.7 1.7e-65 221.9 1.7 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.11 KKK25536.1 - 9.7e-34 115.5 0.1 2.1e-33 114.4 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) Homeobox_KN PF05920.11 KKK25537.1 - 3.7e-19 68.3 0.8 1.3e-18 66.5 0.0 2.4 2 1 0 2 2 2 1 Homeobox KN domain Homeodomain PF00046.29 KKK25537.1 - 0.00021 21.1 0.5 0.15 11.9 0.0 2.3 2 0 0 2 2 2 2 Homeodomain SelB-wing_3 PF09107.11 KKK25537.1 - 0.15 11.8 0.0 0.31 10.7 0.0 1.5 1 0 0 1 1 1 0 Elongation factor SelB, winged helix Trp_DMAT PF11991.8 KKK25538.1 - 2.9e-96 323.0 0.0 3.6e-96 322.7 0.0 1.1 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase p450 PF00067.22 KKK25539.1 - 1.5e-42 146.0 0.0 2.6e-42 145.1 0.0 1.2 1 1 0 1 1 1 1 Cytochrome P450 DivIC PF04977.15 KKK25539.1 - 0.12 12.1 0.3 0.22 11.3 0.3 1.3 1 0 0 1 1 1 0 Septum formation initiator AMP-binding PF00501.28 KKK25540.1 - 1e-141 472.4 0.0 2.6e-73 247.1 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.20 KKK25540.1 - 4.2e-77 259.8 0.0 1.5e-44 152.4 0.0 2.9 2 1 0 2 2 2 2 Condensation domain PP-binding PF00550.25 KKK25540.1 - 1.9e-15 57.0 0.2 3.2e-08 33.8 0.1 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KKK25540.1 - 1.1e-11 45.6 0.9 9.2e-07 29.8 0.4 2.6 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain Aminotran_1_2 PF00155.21 KKK25541.1 - 1e-39 136.8 0.0 1.2e-39 136.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 KKK25541.1 - 0.052 12.8 0.0 0.063 12.5 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase DUF4585 PF15232.6 KKK25541.1 - 0.12 12.5 0.1 0.31 11.1 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4585) Methyltransf_23 PF13489.6 KKK25542.1 - 4.9e-11 42.7 0.0 6.7e-11 42.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKK25542.1 - 0.00011 22.9 0.0 0.00027 21.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KKK25542.1 - 0.0072 16.1 0.0 4.7 7.0 0.0 2.5 3 1 0 3 3 3 2 Methyltransferase domain Methyltransf_12 PF08242.12 KKK25542.1 - 0.0079 16.9 0.0 0.013 16.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KKK25542.1 - 0.066 13.9 0.0 0.13 13.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain VHP PF02209.19 KKK25542.1 - 0.15 12.1 0.2 0.58 10.3 0.1 1.9 2 0 0 2 2 2 0 Villin headpiece domain Pyr_redox_2 PF07992.14 KKK25543.1 - 1.1e-19 70.7 0.1 1.4e-19 70.5 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KKK25543.1 - 3.8e-07 29.7 0.0 0.00086 18.6 0.0 2.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KKK25543.1 - 3.8e-06 26.2 0.4 1.1e-05 24.8 0.1 1.8 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 KKK25543.1 - 2.3e-05 23.3 0.3 0.0013 17.6 0.1 2.2 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.6 KKK25543.1 - 0.00014 22.0 0.0 0.00032 20.9 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 KKK25543.1 - 0.00022 20.5 0.2 0.11 11.5 0.1 3.1 3 0 0 3 3 3 1 Glucose inhibited division protein A DAO PF01266.24 KKK25543.1 - 0.00031 20.4 0.3 0.01 15.4 0.2 2.1 1 1 1 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KKK25543.1 - 0.00035 19.9 0.0 0.00054 19.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 KKK25543.1 - 0.0014 17.9 0.0 0.0027 17.0 0.0 1.4 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.6 KKK25543.1 - 0.0015 18.5 0.4 0.26 11.3 0.1 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_oxidored PF12831.7 KKK25543.1 - 0.019 14.3 0.4 0.028 13.8 0.4 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase K_oxygenase PF13434.6 KKK25543.1 - 0.024 13.8 0.0 4.2 6.4 0.0 2.1 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Glu_dehyd_C PF16912.5 KKK25543.1 - 0.13 11.7 0.1 0.37 10.2 0.0 1.7 1 1 1 2 2 2 0 Glucose dehydrogenase C-terminus Lycopene_cycl PF05834.12 KKK25543.1 - 0.22 10.5 0.6 0.46 9.5 0.3 1.7 1 1 1 2 2 2 0 Lycopene cyclase protein GF_recep_IV PF14843.6 KKK25543.1 - 0.26 11.1 0.2 0.55 10.0 0.2 1.4 1 0 0 1 1 1 0 Growth factor receptor domain IV DUF3632 PF12311.8 KKK25544.1 - 3.5e-30 105.7 0.0 4.8e-30 105.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) Carot_N PF09150.10 KKK25544.1 - 0.13 12.1 0.0 4.3 7.2 0.0 2.7 3 0 0 3 3 3 0 Orange carotenoid protein, N-terminal Bradykinin PF06753.12 KKK25544.1 - 0.35 10.6 3.4 0.14 11.8 0.8 1.7 2 0 0 2 2 2 0 Bradykinin PAP2_3 PF14378.6 KKK25545.1 - 5.9e-24 84.8 11.8 5.9e-24 84.8 11.8 1.8 2 0 0 2 2 2 1 PAP2 superfamily PAP2 PF01569.21 KKK25545.1 - 4.3e-11 42.7 2.1 4.3e-11 42.7 2.1 2.1 2 0 0 2 2 2 1 PAP2 superfamily Glyco_transf_90 PF05686.12 KKK25546.1 - 3.9e-29 101.8 0.4 5.1e-29 101.4 0.4 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 90 Scaffolding_pro PF11418.8 KKK25546.1 - 0.047 14.3 0.0 0.095 13.3 0.0 1.4 1 0 0 1 1 1 0 Phi29 scaffolding protein MU117 PF15474.6 KKK25547.1 - 2.5e-15 57.1 10.5 3.4e-15 56.7 10.5 1.2 1 0 0 1 1 1 1 Meiotically up-regulated gene family RasGAP PF00616.19 KKK25548.1 - 7.8e-60 202.1 0.5 1.7e-59 201.0 0.0 1.9 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 KKK25548.1 - 3.8e-31 108.0 5.5 3.8e-31 108.0 5.5 2.8 3 0 0 3 3 3 1 RasGAP C-terminus LCAT PF02450.15 KKK25550.1 - 8e-104 347.9 0.0 9.5e-104 347.7 0.0 1.1 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase HutD PF05962.11 KKK25550.1 - 0.0057 16.6 0.0 0.0099 15.9 0.0 1.3 1 0 0 1 1 1 1 HutD Acetyltransf_1 PF00583.25 KKK25551.1 - 3.3e-18 66.0 0.0 4.6e-18 65.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KKK25551.1 - 1.1e-11 45.0 0.0 1.6e-11 44.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KKK25551.1 - 1.4e-11 44.2 0.1 2.3e-11 43.5 0.1 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 KKK25551.1 - 1.5e-11 44.3 0.0 2.2e-11 43.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KKK25551.1 - 1.2e-07 32.5 0.0 1.6e-07 32.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 KKK25551.1 - 2.8e-06 27.1 0.0 4.1e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KKK25551.1 - 3.8e-06 27.0 0.0 7e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KKK25551.1 - 0.00035 20.7 0.0 0.00067 19.7 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase GNAT_acetyltran PF12746.7 KKK25551.1 - 0.019 14.5 0.0 0.036 13.6 0.0 1.4 1 0 0 1 1 1 0 GNAT acetyltransferase PanZ PF12568.8 KKK25551.1 - 0.073 12.8 0.1 0.1 12.3 0.1 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_13 PF13880.6 KKK25551.1 - 0.11 12.5 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase Acetyltransf_15 PF17013.5 KKK25551.1 - 0.13 11.7 0.0 0.26 10.7 0.0 1.6 1 1 0 1 1 1 0 Putative acetyl-transferase Methyltransf_23 PF13489.6 KKK25552.1 - 2.4e-09 37.2 0.0 3.3e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKK25552.1 - 3.2e-08 34.2 0.0 5.8e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KKK25552.1 - 3.9e-05 23.5 0.0 5.7e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KKK25552.1 - 0.00025 21.6 0.0 0.00045 20.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KKK25552.1 - 0.0069 15.7 0.0 0.01 15.2 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family HNH_repeat PF18780.1 KKK25552.1 - 0.36 10.7 1.8 1.4 8.8 0.0 2.3 2 0 0 2 2 2 0 Homing endonuclease repeat GST_N_3 PF13417.6 KKK25553.1 - 1.3e-06 28.7 0.0 3.2e-06 27.4 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KKK25553.1 - 6.3e-06 26.3 0.0 1.1e-05 25.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KKK25553.1 - 2.3e-05 24.3 0.1 5.9e-05 23.0 0.1 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KKK25553.1 - 6.4e-05 23.2 0.0 0.00013 22.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KKK25553.1 - 0.0015 18.7 0.0 0.0025 18.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain UPF0149 PF03695.13 KKK25553.1 - 0.02 15.2 0.0 0.029 14.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0149) GST_N PF02798.20 KKK25553.1 - 0.047 14.0 0.0 0.17 12.3 0.0 2.0 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain Mis14 PF08641.12 KKK25554.1 - 3e-31 108.5 8.1 3e-31 108.5 8.1 2.5 3 1 1 4 4 2 1 Kinetochore protein Mis14 like Med17 PF10156.9 KKK25554.1 - 0.00069 18.4 3.5 0.00082 18.2 3.5 1.1 1 0 0 1 1 1 1 Subunit 17 of Mediator complex Myc_N PF01056.18 KKK25554.1 - 0.0038 17.2 5.7 0.0051 16.8 5.7 1.2 1 0 0 1 1 1 1 Myc amino-terminal region DUF4611 PF15387.6 KKK25554.1 - 0.013 15.7 22.7 0.021 15.0 11.9 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4611) CDC45 PF02724.14 KKK25554.1 - 0.036 12.4 19.2 0.046 12.0 19.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Mpp10 PF04006.12 KKK25554.1 - 0.037 12.5 18.3 0.05 12.0 18.3 1.1 1 0 0 1 1 1 0 Mpp10 protein BSP_II PF05432.11 KKK25554.1 - 0.042 13.5 13.8 0.055 13.2 13.8 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) PBP_sp32 PF07222.12 KKK25554.1 - 0.29 10.5 5.2 0.51 9.7 4.8 1.6 2 0 0 2 2 2 0 Proacrosin binding protein sp32 DUF913 PF06025.12 KKK25554.1 - 0.32 9.9 7.3 0.5 9.3 7.3 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Nop14 PF04147.12 KKK25554.1 - 0.38 8.9 18.8 0.49 8.6 18.8 1.2 1 0 0 1 1 1 0 Nop14-like family RR_TM4-6 PF06459.12 KKK25554.1 - 0.62 9.8 12.2 0.86 9.4 12.2 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 TFIIF_alpha PF05793.12 KKK25554.1 - 1.4 7.4 22.7 2 6.9 22.7 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Paf1 PF03985.13 KKK25554.1 - 1.6 7.6 17.0 2.3 7.1 17.0 1.2 1 0 0 1 1 1 0 Paf1 DUF1682 PF07946.14 KKK25554.1 - 1.8 7.7 7.2 3.1 6.9 7.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) DNA_pol_phi PF04931.13 KKK25554.1 - 1.8 6.5 19.7 2.2 6.3 19.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi RRN3 PF05327.11 KKK25554.1 - 2.8 6.4 11.9 3.5 6.1 11.9 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 SAPS PF04499.15 KKK25554.1 - 3.1 6.5 7.0 3.4 6.3 7.0 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Sporozoite_P67 PF05642.11 KKK25554.1 - 3.5 5.6 7.3 4.7 5.2 7.3 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Dicty_REP PF05086.12 KKK25554.1 - 4.4 5.2 6.2 6.4 4.6 6.2 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein ALMT PF11744.8 KKK25554.1 - 4.7 5.9 5.2 6 5.6 5.2 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Hid1 PF12722.7 KKK25554.1 - 4.7 5.2 8.1 5.9 4.9 8.1 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein COPI_C PF06957.11 KKK25554.1 - 8.7 5.0 10.3 12 4.6 10.3 1.2 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus Pes-10 PF07149.11 KKK25554.1 - 9.8 5.1 13.5 13 4.7 13.5 1.2 1 0 0 1 1 1 0 Pes-10 CRAL_TRIO PF00650.20 KKK25555.1 - 5.5e-38 130.2 0.0 1.1e-37 129.3 0.0 1.4 2 0 0 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KKK25555.1 - 9.2e-08 32.2 0.2 2.3e-07 30.9 0.2 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 KKK25555.1 - 0.0016 18.6 0.0 0.0028 17.8 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain TMF_DNA_bd PF12329.8 KKK25555.1 - 0.051 13.6 0.0 7.6 6.6 0.0 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding AAA PF00004.29 KKK25559.1 - 2.4e-11 44.2 0.0 5.2e-11 43.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KKK25559.1 - 1.1e-07 32.2 0.0 2.4e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.15 KKK25559.1 - 6.5e-06 26.2 0.0 3.3e-05 23.9 0.0 2.0 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_33 PF13671.6 KKK25559.1 - 4.6e-05 23.6 0.0 0.00011 22.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KKK25559.1 - 6e-05 23.1 0.0 0.00013 22.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KKK25559.1 - 7.8e-05 22.5 0.0 0.00014 21.7 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain RsgA_GTPase PF03193.16 KKK25559.1 - 0.007 16.3 0.0 0.014 15.4 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 KKK25559.1 - 0.011 16.1 0.0 0.048 14.0 0.0 2.0 1 1 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.6 KKK25559.1 - 0.026 14.1 0.0 0.67 9.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KKK25559.1 - 0.039 14.5 0.0 0.094 13.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KKK25559.1 - 0.073 13.1 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 KKK25559.1 - 0.087 12.2 0.1 0.95 8.8 0.0 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 KKK25559.1 - 0.091 12.5 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_24 PF13479.6 KKK25559.1 - 0.14 11.9 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 KKK25559.1 - 0.15 11.3 0.0 0.43 9.8 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin NB-ARC PF00931.22 KKK25559.1 - 0.15 11.2 0.0 0.36 10.0 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain Snf7 PF03357.21 KKK25559.1 - 0.87 9.2 2.5 7 6.2 1.4 2.2 2 0 0 2 2 2 0 Snf7 YL1 PF05764.13 KKK25560.1 - 0.0011 19.2 2.7 0.0012 19.0 2.7 1.1 1 0 0 1 1 1 1 YL1 nuclear protein adh_short PF00106.25 KKK25561.1 - 4.7e-28 98.0 0.0 6.3e-28 97.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KKK25561.1 - 7.8e-21 74.7 0.0 1e-20 74.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KKK25561.1 - 5.6e-07 29.6 0.0 7.7e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KKK25561.1 - 0.0013 18.3 0.1 0.0049 16.4 0.0 2.0 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family APH PF01636.23 KKK25562.1 - 6.7e-19 68.8 0.0 5.4e-10 39.6 0.0 4.5 4 1 0 4 4 4 3 Phosphotransferase enzyme family TRAPPC9-Trs120 PF08626.11 KKK25563.1 - 0 1494.9 0.0 0 1494.7 0.0 1.0 1 0 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit DIOX_N PF14226.6 KKK25564.1 - 1.8e-36 125.5 0.0 2.5e-33 115.3 0.0 2.4 2 0 0 2 2 2 2 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KKK25564.1 - 2e-14 53.9 0.0 6.1e-14 52.3 0.0 1.8 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Beta_helix PF13229.6 KKK25564.1 - 3.5e-08 33.4 8.8 5.6e-08 32.8 5.0 2.3 1 1 1 2 2 2 2 Right handed beta helix region Chondroitinas_B PF14592.6 KKK25564.1 - 0.019 13.9 0.0 0.029 13.2 0.0 1.2 1 0 0 1 1 1 0 Chondroitinase B DUF1565 PF07602.11 KKK25564.1 - 0.036 13.4 0.2 0.066 12.5 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1565) Glyco_hydro_43 PF04616.14 KKK25565.1 - 2.2e-37 129.0 4.6 2.6e-37 128.7 4.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 C1q PF00386.21 KKK25565.1 - 0.021 15.0 0.9 4.7 7.4 0.1 2.5 2 0 0 2 2 2 0 C1q domain TNF PF00229.18 KKK25565.1 - 0.2 11.6 1.2 19 5.2 0.1 2.4 2 0 0 2 2 2 0 TNF(Tumour Necrosis Factor) family ketoacyl-synt PF00109.26 KKK25566.1 - 6.7e-09 35.7 0.0 9e-09 35.3 0.0 1.2 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 KKK25567.1 - 6.4e-54 182.6 0.2 1.1e-53 181.8 0.2 1.4 1 0 0 1 1 1 1 KR domain ADH_zinc_N_2 PF13602.6 KKK25567.1 - 6.3e-22 79.1 0.0 1.8e-19 71.1 0.0 2.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KKK25567.1 - 9.7e-15 54.7 0.0 3.8e-14 52.8 0.0 2.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.12 KKK25567.1 - 1.7e-10 41.5 0.0 7.1e-10 39.5 0.0 2.1 2 0 0 2 2 1 1 Methyltransferase domain adh_short PF00106.25 KKK25567.1 - 3.3e-10 39.8 0.1 6.5e-10 38.8 0.1 1.5 1 0 0 1 1 1 1 short chain dehydrogenase Methyltransf_23 PF13489.6 KKK25567.1 - 3.7e-08 33.4 0.0 9e-08 32.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain adh_short_C2 PF13561.6 KKK25567.1 - 5.4e-08 32.7 0.1 1e-07 31.7 0.1 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Methyltransf_11 PF08241.12 KKK25567.1 - 3.4e-07 30.8 0.0 2e-06 28.4 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KKK25567.1 - 2.4e-06 27.4 0.0 7.5e-06 25.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKK25567.1 - 7e-06 26.7 0.0 5.4e-05 23.8 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain ketoacyl-synt PF00109.26 KKK25567.1 - 0.00015 21.4 0.0 0.00026 20.7 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ubie_methyltran PF01209.18 KKK25567.1 - 0.0012 18.3 0.0 0.0028 17.0 0.0 1.6 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PP-binding PF00550.25 KKK25567.1 - 0.033 14.5 0.1 0.081 13.3 0.1 1.7 1 0 0 1 1 1 0 Phosphopantetheine attachment site Methyltransf_24 PF13578.6 KKK25567.1 - 0.1 13.6 0.0 1.3 10.1 0.0 2.6 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_16 PF10294.9 KKK25567.1 - 0.19 11.5 0.0 0.66 9.7 0.0 1.9 2 0 0 2 2 2 0 Lysine methyltransferase PBP_like_2 PF12849.7 KKK25568.1 - 1e-13 51.6 3.4 1.3e-13 51.3 3.4 1.1 1 0 0 1 1 1 1 PBP superfamily domain Metallophos PF00149.28 KKK25569.1 - 8.7e-14 52.5 0.0 1.8e-13 51.5 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Lipase_GDSL_2 PF13472.6 KKK25569.1 - 0.053 13.9 0.1 4.1 7.8 0.0 2.9 3 0 0 3 3 3 0 GDSL-like Lipase/Acylhydrolase family RHH_4 PF13467.6 KKK25569.1 - 0.14 12.1 0.0 16 5.4 0.0 3.2 3 0 0 3 3 3 0 Ribbon-helix-helix domain Alpha-L-AF_C PF06964.12 KKK25570.1 - 2.9e-23 82.8 0.0 5.2e-23 82.0 0.0 1.4 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminal domain Tfb5 PF06331.12 KKK25572.1 - 2.1e-20 72.4 0.5 2.1e-20 72.4 0.5 1.5 2 0 0 2 2 2 1 Transcription factor TFIIH complex subunit Tfb5 Fungal_trans PF04082.18 KKK25573.1 - 9.7e-15 54.3 1.1 2.5e-14 52.9 0.0 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK25573.1 - 3.5e-08 33.4 10.2 6.4e-08 32.6 10.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SlyX PF04102.12 KKK25573.1 - 0.094 13.3 1.4 0.35 11.5 0.0 2.5 2 0 0 2 2 2 0 SlyX Cu_amine_oxid PF01179.20 KKK25574.1 - 5.5e-162 539.4 0.0 6.6e-162 539.1 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 KKK25574.1 - 8.1e-05 23.0 0.0 0.00018 21.9 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.16 KKK25574.1 - 0.001 19.3 0.1 0.0021 18.3 0.1 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain DJ-1_PfpI PF01965.24 KKK25575.1 - 2.8e-06 27.2 0.0 7e-05 22.7 0.0 2.1 2 0 0 2 2 2 1 DJ-1/PfpI family ThiJ_like PF17124.5 KKK25575.1 - 0.02 14.6 0.1 0.078 12.7 0.0 1.9 2 0 0 2 2 2 0 ThiJ/PfpI family-like HSP20 PF00011.21 KKK25576.1 - 1.1e-18 67.3 0.8 8.6e-16 57.9 0.8 2.4 1 1 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KKK25576.1 - 2.5e-06 26.9 0.1 1.5e-05 24.4 0.1 2.0 1 1 0 1 1 1 1 HSP20-like domain found in ArsA Afaf PF15339.6 KKK25576.1 - 0.12 12.1 0.2 0.14 11.8 0.2 1.2 1 0 0 1 1 1 0 Acrosome formation-associated factor E1-E2_ATPase PF00122.20 KKK25578.1 - 8.1e-37 126.5 1.4 8.1e-37 126.5 1.4 2.4 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 KKK25578.1 - 8.2e-29 100.6 2.1 8.2e-29 100.6 2.1 2.6 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 KKK25578.1 - 4e-18 65.3 0.0 8e-18 64.3 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KKK25578.1 - 6.8e-09 36.3 0.0 1.7e-08 35.0 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KKK25578.1 - 1e-06 28.3 0.3 4e-06 26.4 0.0 2.2 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus MadL PF03817.13 KKK25578.1 - 0.29 11.2 3.5 0.7 9.9 0.1 2.5 2 0 0 2 2 2 0 Malonate transporter MadL subunit LptF_LptG PF03739.14 KKK25578.1 - 3.5 6.4 8.8 0.1 11.4 2.3 1.7 2 0 0 2 2 2 0 Lipopolysaccharide export system permease LptF/LptG Colicin_V PF02674.16 KKK25578.1 - 5.4 7.0 9.3 0.36 10.8 0.2 3.0 3 0 0 3 3 3 0 Colicin V production protein MFS_1 PF07690.16 KKK25580.1 - 6.4e-21 74.7 23.5 6.4e-21 74.7 23.5 2.4 1 1 2 3 3 3 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KKK25580.1 - 0.0055 15.6 30.2 0.08 11.8 30.2 2.4 1 1 0 1 1 1 1 Sugar (and other) transporter Peptidase_M56 PF05569.11 KKK25580.1 - 0.12 11.6 1.8 0.19 10.9 0.1 2.0 2 0 0 2 2 2 0 BlaR1 peptidase M56 DUF5336 PF17270.2 KKK25580.1 - 0.55 9.8 0.0 0.55 9.8 0.0 3.7 4 0 0 4 4 4 0 Family of unknown function (DUF5336) Phage_holin_7_1 PF16081.5 KKK25580.1 - 1.4 9.1 7.8 0.13 12.4 0.9 2.5 2 1 0 2 2 2 0 Mycobacterial 2 TMS Phage Holin (M2 Hol) Family OATP PF03137.20 KKK25580.1 - 7 4.8 16.6 0.11 10.7 3.4 2.9 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family GWT1 PF06423.12 KKK25580.1 - 8.9 6.4 8.5 2.9 8.0 0.6 3.1 2 1 1 3 3 3 0 GWT1 p450 PF00067.22 KKK25581.1 - 2.3e-44 151.9 0.0 3.2e-44 151.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 PIG-X PF08320.12 KKK25581.1 - 0.032 14.2 0.0 0.14 12.1 0.0 1.9 2 0 0 2 2 2 0 PIG-X / PBN1 COesterase PF00135.28 KKK25582.1 - 5.7e-66 223.4 0.0 8.7e-66 222.8 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KKK25582.1 - 1.6e-06 28.2 0.1 1e-05 25.5 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold PCYCGC PF13798.6 KKK25582.1 - 0.1 12.4 0.1 0.17 11.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function with PCYCGC motif MFS_1 PF07690.16 KKK25583.1 - 1.2e-37 129.7 50.1 4.9e-37 127.7 50.1 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KKK25583.1 - 0.00018 20.1 23.6 0.00036 19.1 23.6 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF2937 PF11157.8 KKK25583.1 - 0.63 9.7 2.9 0.56 9.9 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) OATP PF03137.20 KKK25583.1 - 2.4 6.3 14.9 80 1.3 14.9 2.5 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Epimerase PF01370.21 KKK25585.1 - 1.6e-10 40.9 0.0 1.5e-09 37.7 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KKK25585.1 - 2.7e-07 30.7 0.0 4.6e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 KKK25585.1 - 9.5e-05 21.7 0.4 0.0031 16.7 0.1 2.7 1 1 1 2 2 2 1 Male sterility protein 3Beta_HSD PF01073.19 KKK25585.1 - 9.7e-05 21.5 0.0 0.00032 19.8 0.0 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 KKK25585.1 - 0.002 17.7 0.0 0.003 17.2 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.15 KKK25585.1 - 0.0056 15.8 0.0 0.0087 15.2 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Semialdhyde_dh PF01118.24 KKK25585.1 - 0.031 14.7 0.0 0.055 13.9 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain AA_permease PF00324.21 KKK25586.1 - 1.6e-143 478.8 38.3 1.9e-143 478.6 38.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KKK25586.1 - 3.7e-39 134.8 39.5 4.9e-39 134.4 39.5 1.1 1 0 0 1 1 1 1 Amino acid permease Fungal_trans_2 PF11951.8 KKK25587.1 - 3e-07 29.6 1.1 3.1e-06 26.3 0.0 2.0 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK25587.1 - 1.1e-06 28.6 11.2 1.8e-06 28.0 11.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MIP PF00230.20 KKK25588.1 - 2.8e-41 141.7 6.7 3.8e-41 141.3 6.7 1.1 1 0 0 1 1 1 1 Major intrinsic protein Pectate_lyase PF03211.13 KKK25589.1 - 1.2e-84 282.9 6.5 1.6e-84 282.5 6.5 1.0 1 0 0 1 1 1 1 Pectate lyase Transferase PF02458.15 KKK25590.1 - 1.3e-07 30.7 0.0 0.00069 18.4 0.0 2.1 1 1 1 2 2 2 2 Transferase family AA_permease_2 PF13520.6 KKK25592.1 - 5.5e-65 219.9 33.9 6.7e-65 219.6 33.9 1.0 1 0 0 1 1 1 1 Amino acid permease HsbA PF12296.8 KKK25593.1 - 3e-22 79.3 11.2 3.5e-22 79.1 10.7 1.4 1 1 0 1 1 1 1 Hydrophobic surface binding protein A Formyl_trans_C PF02911.18 KKK25593.1 - 0.11 12.8 0.0 0.17 12.1 0.0 1.3 1 0 0 1 1 1 0 Formyl transferase, C-terminal domain Cytochrom_B562 PF07361.11 KKK25593.1 - 0.15 12.7 0.1 0.95 10.2 0.0 2.1 2 1 0 2 2 2 0 Cytochrome b562 MAPEG PF01124.18 KKK25595.1 - 2.8e-15 56.4 2.1 3.7e-15 56.0 2.1 1.1 1 0 0 1 1 1 1 MAPEG family FA_desaturase PF00487.24 KKK25603.1 - 1.7e-26 93.6 29.5 2.4e-26 93.1 29.5 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 KKK25603.1 - 1.1e-09 38.3 0.0 2.3e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DFP PF04127.15 KKK25604.1 - 3.9e-11 43.1 0.0 1.5e-05 24.9 0.0 2.2 2 0 0 2 2 2 2 DNA / pantothenate metabolism flavoprotein Fringe PF02434.16 KKK25605.1 - 1.9e-09 37.3 0.0 3.3e-08 33.3 0.0 2.1 1 1 0 1 1 1 1 Fringe-like DUF604 PF04646.12 KKK25605.1 - 0.08 12.3 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF604 DUF3896 PF13035.6 KKK25607.1 - 0.075 13.2 0.1 0.38 11.0 0.1 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3896) CENP-O PF09496.10 KKK25608.1 - 1.7e-66 224.2 0.1 8.5e-66 222.0 0.0 1.8 2 0 0 2 2 2 1 Cenp-O kinetochore centromere component Atg29_N PF18388.1 KKK25609.1 - 4.8e-27 93.5 0.7 9.4e-27 92.6 0.7 1.5 1 0 0 1 1 1 1 Atg29 N-terminal domain Abhydrolase_3 PF07859.13 KKK25610.1 - 1.2e-41 142.9 0.0 1.5e-41 142.6 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KKK25610.1 - 2.1e-08 33.9 0.0 7.4e-08 32.1 0.0 1.7 1 1 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.18 KKK25610.1 - 1.5e-06 28.0 0.0 0.0025 17.4 0.0 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family Peptidase_S15 PF02129.18 KKK25610.1 - 0.0015 18.2 0.0 0.0048 16.5 0.0 1.7 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) COesterase PF00135.28 KKK25610.1 - 0.0024 16.8 0.0 0.0074 15.2 0.0 1.6 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_6 PF12697.7 KKK25610.1 - 0.0026 18.4 1.2 0.038 14.6 1.1 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.12 KKK25610.1 - 0.0095 14.6 0.0 1.5 7.4 0.0 2.1 2 0 0 2 2 2 2 Acetyl xylan esterase (AXE1) BAAT_C PF08840.11 KKK25610.1 - 0.013 15.4 0.0 0.022 14.7 0.0 1.4 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_2 PF02230.16 KKK25610.1 - 0.045 13.5 0.0 0.091 12.5 0.0 1.5 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Chlorophyllase2 PF12740.7 KKK25610.1 - 0.16 10.8 0.0 0.23 10.3 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme Acatn PF13000.7 KKK25611.1 - 2.9e-164 547.6 14.4 2.2e-82 277.3 7.0 3.1 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 MFS_1_like PF12832.7 KKK25611.1 - 0.03 13.2 8.2 0.061 12.2 8.2 1.4 1 0 0 1 1 1 0 MFS_1 like family Sugar_tr PF00083.24 KKK25618.1 - 8.1e-94 315.0 21.4 9.8e-94 314.7 21.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKK25618.1 - 9e-15 54.4 40.1 5.8e-09 35.3 10.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans_2 PF11951.8 KKK25619.1 - 1.2e-54 185.6 0.0 1.9e-54 185.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK25619.1 - 2.6e-05 24.2 3.8 5.8e-05 23.1 3.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mannosyl_trans3 PF11051.8 KKK25620.1 - 5.4e-59 199.8 0.0 8.9e-36 123.6 0.0 2.1 1 1 1 2 2 2 2 Mannosyltransferase putative FKBP_C PF00254.28 KKK25623.1 - 2.6e-33 114.2 0.0 3e-33 114.0 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Dynamin_M PF01031.20 KKK25624.1 - 1.7e-101 339.2 0.0 3.5e-101 338.2 0.0 1.5 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 KKK25624.1 - 7.8e-57 192.0 0.1 1.5e-56 191.0 0.1 1.5 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 KKK25624.1 - 2.8e-30 104.3 4.7 2.8e-30 104.3 4.7 2.2 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 KKK25624.1 - 2.4e-05 24.4 0.4 0.0002 21.4 0.4 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF2226 PF09987.9 KKK25624.1 - 0.0027 17.1 0.7 0.35 10.2 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized protein conserved in archaea (DUF2226) FeoB_N PF02421.18 KKK25624.1 - 0.11 12.1 0.3 18 4.8 0.0 2.7 3 0 0 3 3 3 0 Ferrous iron transport protein B BCIP PF13862.6 KKK25634.1 - 9.7e-76 254.1 0.0 1.3e-75 253.7 0.0 1.2 1 0 0 1 1 1 1 p21-C-terminal region-binding protein VID27_N PF17748.1 KKK25634.1 - 0.09 12.6 0.3 0.16 11.8 0.3 1.3 1 0 0 1 1 1 0 VID27 N-terminal region LigB PF02900.18 KKK25636.1 - 0.03 13.4 0.0 0.054 12.5 0.0 1.3 1 0 0 1 1 1 0 Catalytic LigB subunit of aromatic ring-opening dioxygenase WD40 PF00400.32 KKK25637.1 - 2.4e-27 94.6 12.8 1.5e-05 25.6 0.8 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.8 KKK25637.1 - 3.1e-09 36.0 3.2 0.0019 16.9 0.1 5.0 3 1 2 5 5 5 4 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 KKK25637.1 - 1.3e-06 28.6 0.2 0.23 11.8 0.0 4.5 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain APG6_N PF17675.1 KKK25637.1 - 0.0042 17.6 3.3 0.0082 16.7 3.3 1.5 1 0 0 1 1 1 1 Apg6 coiled-coil region Nucleo_P87 PF07267.11 KKK25637.1 - 0.13 11.0 1.3 0.18 10.7 0.6 1.4 1 1 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 ROS_MUCR PF05443.11 KKK25637.1 - 0.16 12.0 1.8 1 9.4 0.3 2.7 3 0 0 3 3 3 0 ROS/MUCR transcriptional regulator protein PEARLI-4 PF05278.12 KKK25637.1 - 0.22 11.1 2.6 0.36 10.4 2.6 1.3 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) Spc24 PF08286.11 KKK25637.1 - 0.62 10.3 3.1 0.33 11.2 0.6 1.8 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 DUF1664 PF07889.12 KKK25637.1 - 2.7 8.0 4.4 8 6.5 1.7 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Sad1_UNC PF07738.13 KKK25638.1 - 4.5e-13 49.3 0.0 1.2e-06 28.6 0.0 2.7 3 0 0 3 3 3 2 Sad1 / UNC-like C-terminal Mid2 PF04478.12 KKK25639.1 - 3.8e-05 23.6 0.0 5.8e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor SKG6 PF08693.10 KKK25639.1 - 0.057 12.8 0.1 0.057 12.8 0.1 1.7 2 0 0 2 2 2 0 Transmembrane alpha-helix domain SSP160 PF06933.11 KKK25639.1 - 0.16 10.1 10.4 0.2 9.8 10.4 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 SAM_2 PF07647.17 KKK25640.1 - 5.9e-16 58.3 0.0 1.7e-15 56.9 0.0 1.8 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KKK25640.1 - 4.5e-12 46.2 0.0 1.5e-11 44.5 0.0 1.8 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) RA PF00788.23 KKK25640.1 - 5.3e-12 46.2 0.0 1.1e-11 45.2 0.0 1.4 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SAM_4 PF18017.1 KKK25640.1 - 0.012 15.5 0.0 0.021 14.8 0.0 1.3 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Nha1_C PF08619.10 KKK25641.1 - 6.1e-94 315.9 18.7 1.3e-93 314.8 18.7 1.4 1 1 0 1 1 1 1 Alkali metal cation/H+ antiporter Nha1 C terminus Na_H_Exchanger PF00999.21 KKK25641.1 - 2.9e-78 263.3 18.4 3.5e-78 263.1 18.4 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Anillin_N PF16018.5 KKK25641.1 - 0.057 14.0 2.0 0.12 13.0 0.3 2.5 2 0 0 2 2 2 0 Anillin N-terminus DUF21 PF01595.20 KKK25641.1 - 0.39 10.4 8.3 0.034 13.9 2.4 2.1 2 0 0 2 2 2 0 Cyclin M transmembrane N-terminal domain Kri1_C PF12936.7 KKK25642.1 - 2.6e-32 110.8 0.5 2.6e-32 110.8 0.5 3.7 2 1 1 3 3 3 1 KRI1-like family C-terminal Kri1 PF05178.12 KKK25642.1 - 5.5e-30 104.0 16.5 5.5e-30 104.0 16.5 4.8 5 1 0 5 5 5 1 KRI1-like family CRISPR_Cse2 PF09485.10 KKK25642.1 - 0.017 15.6 1.3 0.039 14.5 1.3 1.6 1 0 0 1 1 1 0 CRISPR-associated protein Cse2 (CRISPR_cse2) Mito_carr PF00153.27 KKK25643.1 - 1.2e-65 217.4 6.1 2.7e-24 84.9 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Sen15 PF09631.10 KKK25644.1 - 9.7e-10 38.7 0.0 5.8e-08 32.9 0.0 2.1 1 1 0 1 1 1 1 Sen15 protein VASt PF16016.5 KKK25645.1 - 1.6e-32 113.1 0.1 3.6e-32 111.9 0.1 1.7 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain BAR_3 PF16746.5 KKK25645.1 - 1.8e-17 63.8 0.6 3.2e-17 63.1 0.0 1.7 2 0 0 2 2 2 1 BAR domain of APPL family PH PF00169.29 KKK25645.1 - 1.9e-09 38.0 0.0 7.7e-09 36.0 0.0 2.2 2 0 0 2 2 2 1 PH domain GRAM PF02893.20 KKK25645.1 - 0.0005 19.9 0.0 0.0012 18.8 0.0 1.5 1 0 0 1 1 1 1 GRAM domain BAR PF03114.18 KKK25645.1 - 0.0045 16.7 0.6 0.01 15.5 0.6 1.6 1 0 0 1 1 1 1 BAR domain DPBB_1 PF03330.18 KKK25662.1 - 9.6e-05 22.6 0.0 0.00031 20.9 0.0 2.0 1 0 0 1 1 1 1 Lytic transglycolase PAP1 PF08601.10 KKK25662.1 - 3 7.5 25.5 3.7 7.2 25.5 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 DUF572 PF04502.13 KKK25662.1 - 8 6.0 9.3 10 5.6 9.3 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) VirB3 PF05101.13 KKK25663.1 - 0.03 14.6 3.8 0.04 14.1 3.8 1.2 1 0 0 1 1 1 0 Type IV secretory pathway, VirB3-like protein Hexapep PF00132.24 KKK25680.1 - 5.5e-13 48.1 7.7 4.5e-10 38.8 3.4 3.6 3 0 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Mac PF12464.8 KKK25680.1 - 8.6e-13 48.3 0.1 1.4e-12 47.7 0.1 1.3 1 0 0 1 1 1 1 Maltose acetyltransferase Hexapep_2 PF14602.6 KKK25680.1 - 7.2e-11 41.7 7.0 1.6e-08 34.1 3.1 3.4 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase DUF2613 PF11021.8 KKK25680.1 - 0.9 9.7 4.6 4 7.6 2.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2613) ABC_membrane PF00664.23 KKK25681.1 - 2.9e-92 309.2 20.5 6.6e-51 173.6 3.1 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KKK25681.1 - 4.8e-61 205.3 0.0 1.3e-29 103.4 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KKK25681.1 - 1.1e-16 61.0 0.4 6.7e-05 22.4 0.0 4.3 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KKK25681.1 - 1.3e-08 34.4 0.1 0.0023 17.7 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 KKK25681.1 - 1.1e-07 32.3 1.3 0.04 14.2 0.1 4.2 2 2 1 3 3 3 2 AAA domain AAA_16 PF13191.6 KKK25681.1 - 2.3e-06 28.1 1.0 0.051 13.9 0.0 3.2 2 1 0 2 2 2 2 AAA ATPase domain DUF87 PF01935.17 KKK25681.1 - 2.1e-05 24.8 0.4 0.006 16.7 0.2 2.6 2 1 0 2 2 2 1 Helicase HerA, central domain RsgA_GTPase PF03193.16 KKK25681.1 - 6.6e-05 22.9 0.0 0.064 13.2 0.0 2.6 2 0 0 2 2 2 1 RsgA GTPase APS_kinase PF01583.20 KKK25681.1 - 0.00012 22.0 0.0 0.14 12.1 0.0 2.6 2 0 0 2 2 2 2 Adenylylsulphate kinase AAA_30 PF13604.6 KKK25681.1 - 0.00013 21.8 1.2 0.63 9.7 0.0 3.8 3 1 0 3 3 3 2 AAA domain AAA_18 PF13238.6 KKK25681.1 - 0.0002 21.9 0.0 0.71 10.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.6 KKK25681.1 - 0.00054 20.5 6.4 0.25 11.8 0.1 3.3 3 0 0 3 3 3 2 AAA domain AAA PF00004.29 KKK25681.1 - 0.00063 20.2 0.5 7.9 6.9 0.2 4.2 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 KKK25681.1 - 0.00086 18.6 0.0 0.84 8.9 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin AAA_33 PF13671.6 KKK25681.1 - 0.0011 19.1 0.0 2.3 8.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 KKK25681.1 - 0.0026 17.3 0.5 2.5 7.6 0.0 3.7 4 0 0 4 4 4 1 AAA domain ABC_ATPase PF09818.9 KKK25681.1 - 0.0058 15.5 0.3 0.25 10.1 0.0 2.5 2 0 0 2 2 2 1 Predicted ATPase of the ABC class DUF3987 PF13148.6 KKK25681.1 - 0.0075 15.3 2.7 0.081 11.9 0.0 2.8 3 0 0 3 3 2 1 Protein of unknown function (DUF3987) KdpD PF02702.17 KKK25681.1 - 0.0086 15.6 0.0 0.29 10.6 0.0 2.4 2 0 0 2 2 2 1 Osmosensitive K+ channel His kinase sensor domain DEAD PF00270.29 KKK25681.1 - 0.024 14.4 0.0 0.38 10.5 0.0 2.8 3 1 0 3 3 3 0 DEAD/DEAH box helicase AAA_7 PF12775.7 KKK25681.1 - 0.025 14.1 0.0 4.3 6.8 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_21 PF13304.6 KKK25681.1 - 0.08 12.7 0.0 6.1 6.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 KKK25681.1 - 0.088 12.5 0.6 8.6 6.0 0.0 2.5 3 0 0 3 3 2 0 AAA ATPase domain AAA_24 PF13479.6 KKK25681.1 - 0.097 12.4 0.0 7.7 6.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 KKK25681.1 - 0.1 12.6 0.0 18 5.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Rad17 PF03215.15 KKK25681.1 - 0.13 12.2 0.0 0.76 9.7 0.0 2.1 2 0 0 2 2 2 0 Rad17 P-loop domain NB-ARC PF00931.22 KKK25681.1 - 0.14 11.4 0.0 7.1 5.7 0.0 2.5 3 0 0 3 3 2 0 NB-ARC domain AAA_17 PF13207.6 KKK25681.1 - 0.15 12.5 0.0 18 5.7 0.0 2.8 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 KKK25681.1 - 0.16 12.1 0.0 27 4.9 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase SbcCD_C PF13558.6 KKK25681.1 - 0.16 12.2 2.1 23 5.3 0.1 3.4 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit G-alpha PF00503.20 KKK25681.1 - 0.16 11.1 0.0 7 5.7 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit Radial_spoke PF04712.12 KKK25681.1 - 0.26 10.2 5.3 0.38 9.6 5.3 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein Ribosomal_60s PF00428.19 KKK25681.1 - 1.1 9.8 11.1 4.2 8.0 11.1 1.9 1 0 0 1 1 1 0 60s Acidic ribosomal protein CENP-B_dimeris PF09026.10 KKK25681.1 - 2.1 8.8 4.2 5.5 7.5 4.2 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Cad PF03596.13 KKK25681.1 - 6.7 6.6 7.6 0.55 10.1 0.6 2.7 3 0 0 3 3 2 0 Cadmium resistance transporter MFS_1 PF07690.16 KKK25682.1 - 4.5e-18 65.3 10.4 5.4e-18 65.0 10.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily UQ_con PF00179.26 KKK25684.1 - 2.1e-41 140.9 0.0 3.1e-41 140.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KKK25684.1 - 0.0003 20.5 0.0 0.00062 19.5 0.0 1.5 1 1 0 1 1 1 1 Prokaryotic E2 family B UFC1 PF08694.11 KKK25684.1 - 0.11 12.1 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 RWD PF05773.22 KKK25684.1 - 0.14 12.5 0.1 0.26 11.6 0.1 1.5 1 0 0 1 1 1 0 RWD domain HhH-GPD PF00730.25 KKK25686.1 - 3.9e-20 72.3 0.0 1.1e-19 70.9 0.0 1.7 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 KKK25686.1 - 2.2e-06 27.2 0.0 5.1e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif Adaptin_N PF01602.20 KKK25687.1 - 1.1e-104 350.9 0.0 1.7e-104 350.3 0.0 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KKK25687.1 - 1.4e-16 60.9 0.0 4.4e-13 49.6 0.0 3.5 2 2 2 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KKK25687.1 - 1.3e-08 35.1 2.7 0.0043 17.4 0.0 5.1 4 1 1 5 5 5 3 HEAT repeats HEAT PF02985.22 KKK25687.1 - 1.6e-07 31.0 0.2 0.048 13.9 0.0 5.0 6 0 0 6 6 6 2 HEAT repeat Arm PF00514.23 KKK25687.1 - 0.0034 17.4 2.8 0.97 9.6 0.1 5.0 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat RICTOR_N PF14664.6 KKK25687.1 - 0.019 14.0 0.0 2.7 6.9 0.0 2.6 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR, N-term Cohesin_HEAT PF12765.7 KKK25687.1 - 0.022 15.1 0.2 0.47 10.8 0.0 3.0 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion MOR2-PAG1_N PF14222.6 KKK25687.1 - 0.038 12.9 0.1 0.068 12.1 0.1 1.3 1 0 0 1 1 1 0 Cell morphogenesis N-terminal Cnd3 PF12719.7 KKK25687.1 - 0.37 9.9 4.3 0.41 9.8 0.0 2.9 3 1 0 4 4 4 0 Nuclear condensing complex subunits, C-term domain Metallophos PF00149.28 KKK25688.1 - 3.9e-36 125.5 0.2 5.5e-36 125.0 0.2 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KKK25688.1 - 0.014 15.8 0.3 0.044 14.2 0.3 1.9 1 1 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain Metallophos_2 PF12850.7 KKK25688.1 - 0.11 12.7 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain IF-2B PF01008.17 KKK25689.1 - 7.8e-48 163.1 0.0 2.1e-47 161.7 0.0 1.6 1 1 0 1 1 1 1 Initiation factor 2 subunit family Nuf2 PF03800.14 KKK25690.1 - 3.3e-43 147.2 0.0 8.9e-43 145.7 0.0 1.8 1 0 0 1 1 1 1 Nuf2 family DHR10 PF18595.1 KKK25690.1 - 4.1e-35 120.3 23.1 4.1e-35 120.3 23.1 3.5 3 0 0 3 3 3 2 Designed helical repeat protein 10 domain Apolipoprotein PF01442.18 KKK25690.1 - 0.0026 17.7 24.1 0.0026 17.7 24.1 2.5 1 1 1 2 2 2 1 Apolipoprotein A1/A4/E domain Bacillus_HBL PF05791.11 KKK25690.1 - 0.83 9.5 18.3 0.16 11.8 3.5 3.4 1 1 1 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) MobC PF05713.11 KKK25690.1 - 1.6 9.2 4.7 3.5 8.2 0.5 3.6 3 0 0 3 3 3 0 Bacterial mobilisation protein (MobC) Laminin_II PF06009.12 KKK25690.1 - 2.8 7.9 35.7 1.8 8.6 11.5 3.4 1 1 1 3 3 3 0 Laminin Domain II Spc7 PF08317.11 KKK25690.1 - 7.8 5.3 56.9 2.5 6.9 17.3 3.1 1 1 2 3 3 3 0 Spc7 kinetochore protein Fungal_trans PF04082.18 KKK25692.1 - 4.6e-08 32.4 0.2 7.8e-08 31.7 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK25692.1 - 3.4e-06 27.1 8.8 5.9e-06 26.3 8.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Smg4_UPF3 PF03467.15 KKK25693.1 - 2.5e-37 128.6 0.0 2.5e-37 128.6 0.0 2.7 3 0 0 3 3 3 1 Smg-4/UPF3 family RRM_1 PF00076.22 KKK25693.1 - 4.8e-09 35.9 0.2 4.7e-07 29.5 0.0 3.1 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KKK25693.1 - 0.039 14.0 0.1 0.12 12.4 0.0 1.8 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Pep1_7 PF17232.2 KKK25693.1 - 0.096 13.2 0.2 0.096 13.2 0.2 2.8 3 0 0 3 3 3 0 Elicitor peptide 1-7 Wyosine_form PF08608.12 KKK25694.1 - 1.2e-24 86.4 0.0 2.5e-24 85.4 0.0 1.6 1 0 0 1 1 1 1 Wyosine base formation Radical_SAM PF04055.21 KKK25694.1 - 1.3e-13 51.7 0.0 4.7e-13 49.9 0.0 1.9 1 1 0 1 1 1 1 Radical SAM superfamily Flavodoxin_1 PF00258.25 KKK25694.1 - 1.6e-09 38.1 1.0 7e-07 29.5 1.0 2.6 1 1 0 1 1 1 1 Flavodoxin Sugar_tr PF00083.24 KKK25695.1 - 9.7e-61 206.0 14.0 1.2e-60 205.7 14.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKK25695.1 - 1.7e-15 56.8 31.5 4.6e-12 45.5 13.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KKK25695.1 - 0.0021 16.7 9.0 0.0021 16.7 9.0 3.1 2 1 1 3 3 3 2 MFS/sugar transport protein C_GCAxxG_C_C PF09719.10 KKK25695.1 - 0.15 12.3 0.2 5 7.4 0.2 2.6 2 0 0 2 2 2 0 Putative redox-active protein (C_GCAxxG_C_C) Metallophos PF00149.28 KKK25696.1 - 4.5e-35 122.0 0.0 5e-34 118.6 0.0 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Glyco_hydro_65N PF03636.15 KKK25696.1 - 0.099 12.3 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain NUDIX PF00293.28 KKK25697.1 - 9.4e-14 51.6 1.4 1.5e-12 47.7 1.4 2.1 1 1 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 KKK25697.1 - 0.14 12.1 0.1 1.3 9.1 0.1 2.2 1 1 0 1 1 1 0 NUDIX domain WD40 PF00400.32 KKK25698.1 - 1.2e-16 60.7 0.4 0.00033 21.4 0.0 5.4 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKK25698.1 - 8.6e-05 22.8 0.0 1.3 9.4 0.0 3.4 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 KKK25698.1 - 0.00044 19.1 0.1 0.66 8.7 0.0 3.0 2 1 0 3 3 3 2 Nup133 N terminal like Nup160 PF11715.8 KKK25698.1 - 0.11 11.1 0.0 2.7 6.5 0.0 2.6 2 1 1 3 3 3 0 Nucleoporin Nup120/160 APH PF01636.23 KKK25699.1 - 3.2e-09 37.1 0.2 7.7e-09 35.8 0.0 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family DUF1679 PF07914.11 KKK25699.1 - 0.012 14.5 0.0 0.022 13.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Myb_DNA-binding PF00249.31 KKK25701.1 - 8.4e-27 93.1 1.6 2.5e-16 59.6 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KKK25701.1 - 2.8e-19 69.1 5.1 1.1e-15 57.6 0.1 2.8 2 1 1 3 3 3 2 Myb-like DNA-binding domain DUF2774 PF11242.8 KKK25701.1 - 0.033 14.4 0.0 0.075 13.2 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2774) Myb_DNA-bind_4 PF13837.6 KKK25701.1 - 0.047 14.1 0.3 0.21 12.0 0.0 2.2 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain ATE_C PF04377.15 KKK25707.1 - 3.8e-49 166.7 2.6 6e-49 166.1 2.6 1.3 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.13 KKK25707.1 - 1e-17 64.3 0.4 1e-17 64.3 0.4 2.1 2 1 0 2 2 2 1 Arginine-tRNA-protein transferase, N terminus Acetyltransf_6 PF13480.7 KKK25707.1 - 5.6e-05 23.3 0.1 0.00011 22.4 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Kelch_2 PF07646.15 KKK25707.1 - 0.0043 17.0 0.2 0.23 11.5 0.0 2.6 2 0 0 2 2 2 1 Kelch motif PRP3 PF08572.10 KKK25708.1 - 0.0077 16.0 0.4 0.013 15.3 0.4 1.4 1 1 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) Fmp27 PF10344.9 KKK25708.1 - 0.18 9.8 0.0 0.23 9.5 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial protein from FMP27 Cytochrom_C PF00034.21 KKK25709.1 - 7.3e-12 46.3 0.1 1.2e-11 45.6 0.1 1.3 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 KKK25709.1 - 3.6e-07 30.4 2.2 4.5e-06 26.9 2.2 2.1 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 KKK25709.1 - 7.4e-05 22.5 0.1 0.00017 21.3 0.0 1.6 2 0 0 2 2 2 1 Cytochrome c-550 domain Cytochrome-c551 PF10643.9 KKK25709.1 - 0.017 14.7 0.1 0.019 14.6 0.1 1.2 1 0 0 1 1 1 0 Photosystem P840 reaction-centre cytochrome c-551 Haem_bd PF14376.6 KKK25709.1 - 0.086 12.8 0.1 0.14 12.1 0.1 1.3 1 0 0 1 1 1 0 Haem-binding domain RNase_PH PF01138.21 KKK25710.1 - 5e-11 43.2 0.0 9.6e-11 42.3 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KKK25710.1 - 0.026 14.6 0.0 0.86 9.7 0.0 2.4 2 0 0 2 2 2 0 3' exoribonuclease family, domain 2 Baculo_PEP_C PF04513.12 KKK25711.1 - 0.098 12.7 2.7 0.32 11.0 0.1 2.4 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus RNA_pol_A_bac PF01000.26 KKK25712.1 - 6.4e-32 110.2 0.0 1e-31 109.6 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 KKK25712.1 - 7.4e-17 60.6 0.0 9.8e-17 60.2 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain NUDIX PF00293.28 KKK25713.1 - 1.4e-16 60.7 0.1 1.7e-16 60.4 0.1 1.1 1 0 0 1 1 1 1 NUDIX domain RRM_1 PF00076.22 KKK25714.1 - 1.5e-07 31.2 0.0 3.8e-07 29.8 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KKK25714.1 - 2.5e-06 27.4 0.0 4.5e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif FAM153 PF15722.5 KKK25714.1 - 0.044 14.1 1.1 0.089 13.1 0.3 2.0 1 1 1 2 2 2 0 FAM153 family MapZ_C2 PF18708.1 KKK25714.1 - 0.16 12.3 0.0 0.33 11.3 0.0 1.6 1 1 0 1 1 1 0 MapZ extracellular C-terminal domain 2 YhdX PF17444.2 KKK25714.1 - 0.22 11.4 1.7 2.8 7.8 0.9 2.4 2 0 0 2 2 2 0 Uncharacterized YhdX-like IBN_N PF03810.19 KKK25715.1 - 4.6e-18 64.9 2.1 1.1e-14 54.1 0.0 4.3 4 0 0 4 4 4 1 Importin-beta N-terminal domain Cse1 PF08506.10 KKK25715.1 - 2.3e-07 30.0 0.0 5.7e-07 28.7 0.0 1.7 1 0 0 1 1 1 1 Cse1 RTP1_C1 PF10363.9 KKK25715.1 - 0.00089 19.4 0.3 0.23 11.6 0.1 3.0 2 0 0 2 2 2 1 Required for nuclear transport of RNA pol II C-terminus 1 Xpo1 PF08389.12 KKK25715.1 - 0.0074 16.4 1.8 0.15 12.1 0.0 3.5 3 1 0 3 3 3 1 Exportin 1-like protein DCB PF16213.5 KKK25715.1 - 0.16 11.6 0.2 0.46 10.1 0.2 1.8 1 0 0 1 1 1 0 Dimerisation and cyclophilin-binding domain of Mon2 HEAT_EZ PF13513.6 KKK25715.1 - 1.3 9.6 7.8 24 5.6 0.6 5.4 6 2 1 7 7 7 0 HEAT-like repeat DSHCT PF08148.12 KKK25716.1 - 8.5e-52 175.1 0.5 2.5e-51 173.6 0.5 1.9 1 0 0 1 1 1 1 DSHCT (NUC185) domain Ski2_N PF17911.1 KKK25716.1 - 2.6e-40 137.4 0.0 5.9e-40 136.2 0.0 1.6 1 0 0 1 1 1 1 Ski2 N-terminal region rRNA_proc-arch PF13234.6 KKK25716.1 - 1.9e-25 90.3 0.2 5e-25 89.0 0.0 1.8 2 0 0 2 2 2 1 rRNA-processing arch domain DEAD PF00270.29 KKK25716.1 - 3.5e-18 66.0 0.0 7.5e-18 64.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KKK25716.1 - 1.1e-06 28.9 0.0 3.6e-06 27.3 0.0 1.9 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KKK25716.1 - 9.4e-06 25.7 0.0 2.3e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2415 PF10313.9 KKK25717.1 - 2.5e-15 56.1 0.1 7.9e-15 54.5 0.0 2.0 2 0 0 2 2 2 1 Uncharacterised protein domain (DUF2415) NAM-associated PF14303.6 KKK25717.1 - 5.2 7.8 5.4 4.5 8.0 3.8 1.7 1 1 0 1 1 1 0 No apical meristem-associated C-terminal domain HSP70 PF00012.20 KKK25718.1 - 2.5e-267 887.9 18.5 2.9e-267 887.8 18.5 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KKK25718.1 - 6.8e-16 58.0 8.2 2.2e-14 53.0 2.0 3.0 3 0 0 3 3 3 2 MreB/Mbl protein FGGY_C PF02782.16 KKK25718.1 - 0.0005 19.8 0.0 0.0012 18.6 0.0 1.8 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain MukF_M PF17192.4 KKK25718.1 - 0.073 12.8 1.3 0.17 11.6 1.3 1.6 1 0 0 1 1 1 0 MukF middle domain Big_3_4 PF13754.6 KKK25718.1 - 0.079 12.7 0.0 2.6 7.8 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function Tom22 PF04281.13 KKK25718.1 - 0.14 12.0 6.3 0.36 10.6 6.3 1.7 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 SMBP PF16785.5 KKK25718.1 - 1.1 9.6 5.0 0.88 9.8 2.6 2.2 2 0 0 2 2 2 0 Small metal-binding protein HA2 PF04408.23 KKK25720.1 - 7.6e-17 61.6 0.1 3.1e-16 59.6 0.1 2.1 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KKK25720.1 - 3.9e-14 52.9 0.1 1.1e-13 51.5 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KKK25720.1 - 3.9e-12 46.3 0.0 7.9e-12 45.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KKK25720.1 - 1.7e-05 25.1 0.1 6.5e-05 23.2 0.1 2.0 1 0 0 1 1 1 1 AAA domain OB_NTP_bind PF07717.16 KKK25720.1 - 4.4e-05 23.8 0.0 0.00011 22.5 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Gcn1_N PF12074.8 KKK25721.1 - 1.1e-122 409.7 3.4 1.1e-122 409.7 3.4 3.7 4 0 0 4 4 4 1 Generalcontrol nonderepressible 1 (Gcn1) N-terminal Ribosomal_L19e PF01280.20 KKK25721.1 - 7.8e-59 197.9 8.5 1.9e-58 196.6 8.5 1.7 1 0 0 1 1 1 1 Ribosomal protein L19e HEAT PF02985.22 KKK25721.1 - 1.4e-27 93.4 26.6 0.18 12.1 0.1 20.4 21 0 0 21 21 20 6 HEAT repeat HEAT_2 PF13646.6 KKK25721.1 - 2.8e-27 94.9 25.8 3.8e-07 30.4 1.2 13.2 9 3 4 13 13 13 9 HEAT repeats HEAT_EZ PF13513.6 KKK25721.1 - 1.2e-23 83.2 40.6 0.00076 19.9 0.1 19.1 16 5 6 22 22 20 5 HEAT-like repeat Cnd1 PF12717.7 KKK25721.1 - 1.6e-12 47.8 11.2 0.066 13.3 0.1 8.8 6 2 2 9 9 9 4 non-SMC mitotic condensation complex subunit 1 ParcG PF10274.9 KKK25721.1 - 1.7e-09 38.1 6.2 0.15 12.2 0.1 6.7 5 1 1 6 6 6 2 Parkin co-regulated protein CLASP_N PF12348.8 KKK25721.1 - 4.5e-09 36.2 0.0 1.2 8.6 0.0 7.0 4 2 2 7 7 7 2 CLASP N terminal Vac14_Fab1_bd PF12755.7 KKK25721.1 - 8.3e-09 35.9 0.0 7.4 7.2 0.0 8.3 7 2 3 10 10 9 1 Vacuolar 14 Fab1-binding region TIP120 PF08623.10 KKK25721.1 - 3.8e-06 26.8 0.2 0.003 17.4 0.0 5.3 5 1 1 6 6 6 1 TATA-binding protein interacting (TIP20) Cnd3 PF12719.7 KKK25721.1 - 0.00031 20.0 6.4 0.18 11.0 0.0 4.4 3 0 0 3 3 3 2 Nuclear condensing complex subunits, C-term domain Ipi1_N PF12333.8 KKK25721.1 - 0.0021 18.6 0.8 4.4 8.0 0.0 4.6 5 0 0 5 5 3 1 Rix1 complex component involved in 60S ribosome maturation DUF937 PF06078.11 KKK25721.1 - 0.0041 17.7 3.2 13 6.4 0.0 5.9 4 1 1 5 5 5 0 Bacterial protein of unknown function (DUF937) RTP1_C1 PF10363.9 KKK25721.1 - 0.088 13.0 14.2 3.2 8.0 0.1 7.1 8 0 0 8 8 7 0 Required for nuclear transport of RNA pol II C-terminus 1 DUF4487 PF14868.6 KKK25721.1 - 0.18 10.6 4.9 0.25 10.1 1.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4487) Dopey_N PF04118.14 KKK25721.1 - 1.6 7.7 5.6 51 2.8 0.0 5.1 5 1 0 5 5 5 0 Dopey, N-terminal V-ATPase_H_N PF03224.14 KKK25721.1 - 3.8 6.7 8.3 41 3.3 0.0 4.5 4 0 0 4 4 4 0 V-ATPase subunit H ANAPC4_WD40 PF12894.7 KKK25722.1 - 4.6e-07 30.0 0.0 0.23 11.8 0.0 3.6 3 0 0 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KKK25722.1 - 4.9e-07 30.3 4.4 0.00072 20.3 0.0 5.6 6 0 0 6 6 6 1 WD domain, G-beta repeat Sugar_tr PF00083.24 KKK25753.1 - 4.6e-26 91.7 16.4 5.8e-26 91.4 16.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KKK25753.1 - 1e-09 37.8 18.0 1.5e-09 37.2 18.0 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily GtrA PF04138.14 KKK25753.1 - 0.0087 16.3 2.3 0.16 12.2 0.1 2.6 2 1 1 3 3 2 1 GtrA-like protein Acetate_kinase PF00871.17 KKK25754.1 - 4.6e-87 292.3 0.0 5.5e-87 292.0 0.0 1.1 1 0 0 1 1 1 1 Acetokinase family Cyclin PF08613.11 KKK25755.1 - 7e-12 46.0 0.0 1e-11 45.5 0.0 1.2 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 KKK25755.1 - 4.8e-05 23.1 0.0 8e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain MARVEL PF01284.23 KKK25756.1 - 9.4e-22 77.6 15.3 1.1e-21 77.4 15.3 1.0 1 0 0 1 1 1 1 Membrane-associating domain Cys_Met_Meta_PP PF01053.20 KKK25757.1 - 3.3e-128 427.4 0.0 3.8e-128 427.3 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 KKK25757.1 - 4.7e-11 42.6 1.0 8.8e-11 41.7 1.0 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 KKK25757.1 - 1.4e-08 34.4 0.2 2.2e-08 33.7 0.2 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KKK25757.1 - 1e-07 31.3 0.4 3e-07 29.7 0.4 1.6 1 1 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KKK25757.1 - 2.5e-05 23.7 0.0 4.4e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Met_gamma_lyase PF06838.11 KKK25757.1 - 0.00022 19.9 0.0 0.00027 19.6 0.0 1.1 1 0 0 1 1 1 1 Methionine gamma-lyase Asparaginase_C PF17763.1 KKK25757.1 - 0.0012 19.1 0.5 0.0051 17.0 0.1 2.2 2 0 0 2 2 2 1 Glutaminase/Asparaginase C-terminal domain SepSecS PF05889.13 KKK25757.1 - 0.079 11.6 0.0 0.11 11.1 0.0 1.2 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS GDC-P PF02347.16 KKK25757.1 - 0.19 10.5 0.0 0.25 10.1 0.0 1.1 1 0 0 1 1 1 0 Glycine cleavage system P-protein Ribosomal_L7Ae PF01248.26 KKK25785.1 - 3.3e-24 84.4 0.0 3.7e-24 84.3 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Sua5_yciO_yrdC PF01300.18 KKK25787.1 - 1.7e-54 184.1 0.0 3.8e-54 182.9 0.0 1.6 1 0 0 1 1 1 1 Telomere recombination NFACT-C PF11923.8 KKK25787.1 - 1.6e-40 137.3 0.2 1.6e-40 137.3 0.2 3.6 4 0 0 4 4 4 1 NFACT protein C-terminal domain SUA5 PF03481.13 KKK25787.1 - 8.9e-32 110.5 0.0 8.9e-32 110.5 0.0 3.5 5 0 0 5 5 5 1 Putative GTP-binding controlling metal-binding FbpA PF05833.11 KKK25787.1 - 2.7e-27 95.6 13.7 6.4e-22 77.9 0.1 3.2 3 0 0 3 3 3 2 Fibronectin-binding protein A N-terminus (FbpA) NFACT-R_1 PF05670.13 KKK25787.1 - 3.5e-27 95.2 0.0 1.6e-26 93.1 0.0 2.1 2 0 0 2 2 2 1 NFACT protein RNA binding domain Clat_adaptor_s PF01217.20 KKK25787.1 - 4.8e-10 39.5 0.0 2.1e-08 34.2 0.1 2.8 3 0 0 3 3 3 1 Clathrin adaptor complex small chain PIG-L PF02585.17 KKK25787.1 - 0.76 10.4 3.0 2.5 8.8 0.0 2.8 2 0 0 2 2 2 0 GlcNAc-PI de-N-acetylase Ribosomal_L16 PF00252.18 KKK25788.1 - 5.6e-44 149.3 0.1 7e-44 149.0 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e PALP PF00291.25 KKK25789.1 - 8.7e-08 31.9 0.0 1.5e-07 31.2 0.0 1.5 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme IlvN PF07991.12 KKK25790.1 - 5.7e-46 156.1 0.0 8.6e-46 155.5 0.0 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain IlvC PF01450.19 KKK25790.1 - 3.8e-40 137.5 0.0 7.4e-40 136.6 0.0 1.5 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_2 PF03446.15 KKK25790.1 - 0.031 14.4 0.0 0.055 13.6 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 KKK25790.1 - 0.1 13.2 0.0 0.26 11.9 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 2OG-FeII_Oxy_2 PF13532.6 KKK25791.1 - 9.2e-23 81.4 0.0 1.6e-22 80.7 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Isochorismatase PF00857.20 KKK25791.1 - 5.1e-21 75.6 0.0 9e-20 71.6 0.0 2.8 1 1 1 2 2 2 1 Isochorismatase family GST_C_2 PF13410.6 KKK25791.1 - 8.4e-05 22.5 0.0 0.00017 21.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KKK25791.1 - 0.00026 21.1 0.0 0.00048 20.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KKK25791.1 - 0.067 13.4 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Glutaredoxin2_C PF04399.13 KKK25791.1 - 0.13 12.1 0.0 0.29 10.9 0.0 1.5 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain ECH_1 PF00378.20 KKK25792.1 - 2e-27 96.1 0.5 4.7e-27 94.9 0.1 1.6 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KKK25792.1 - 2.2e-15 57.0 0.0 1.5e-13 51.0 0.0 2.3 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Glyco_hydro_43 PF04616.14 KKK25793.1 - 6.7e-34 117.5 0.0 8.8e-34 117.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Glyco_transf_90 PF05686.12 KKK25794.1 - 2.4e-28 99.2 0.0 3.8e-28 98.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 90 Glyco_trans_1_2 PF13524.6 KKK25794.1 - 0.001 19.4 0.0 0.0019 18.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Kinesin PF00225.23 KKK25795.1 - 1.5e-111 372.5 0.0 2.4e-111 371.9 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain DUF3694 PF12473.8 KKK25795.1 - 3.4e-45 154.5 0.2 1.6e-44 152.3 0.1 2.2 2 0 0 2 2 2 1 Kinesin protein Kinesin_assoc PF16183.5 KKK25795.1 - 3.5e-36 125.0 13.4 1.9e-30 106.4 0.6 3.4 3 1 1 4 4 4 2 Kinesin-associated Microtub_bd PF16796.5 KKK25795.1 - 1.9e-25 89.5 0.0 5.1e-25 88.1 0.0 1.8 1 0 0 1 1 1 1 Microtubule binding KIF1B PF12423.8 KKK25795.1 - 3e-07 30.8 0.1 3e-07 30.8 0.1 2.5 2 0 0 2 2 2 1 Kinesin protein 1B PH PF00169.29 KKK25795.1 - 9.4e-07 29.3 0.0 2.3e-06 28.0 0.0 1.7 1 0 0 1 1 1 1 PH domain FHA PF00498.26 KKK25795.1 - 0.00012 22.3 0.6 0.00091 19.5 0.0 2.8 3 0 0 3 3 3 1 FHA domain Nas2_N PF18265.1 KKK25795.1 - 0.43 10.5 2.2 0.77 9.7 0.1 2.6 2 0 0 2 2 2 0 Nas2 N_terminal domain UPF0242 PF06785.11 KKK25795.1 - 1.8 8.6 9.8 6.4 6.8 0.5 2.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Phosphodiest PF01663.22 KKK25798.1 - 6.7e-87 292.4 0.1 9.5e-87 291.9 0.1 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 KKK25798.1 - 0.002 17.6 0.2 1.5 8.1 0.0 2.2 1 1 1 2 2 2 2 Sulfatase Metalloenzyme PF01676.18 KKK25798.1 - 0.011 15.1 0.0 0.02 14.3 0.0 1.3 1 0 0 1 1 1 0 Metalloenzyme superfamily PglZ PF08665.12 KKK25798.1 - 0.019 15.1 0.0 0.093 12.8 0.0 2.0 2 0 0 2 2 2 0 PglZ domain DUF229 PF02995.17 KKK25798.1 - 0.19 10.3 0.0 0.28 9.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF229) BCS1_N PF08740.11 KKK25799.1 - 2.6e-48 164.5 0.1 2.6e-48 164.5 0.1 1.8 2 0 0 2 2 1 1 BCS1 N terminal AAA PF00004.29 KKK25799.1 - 2.7e-15 57.0 0.0 5.8e-07 30.0 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 KKK25799.1 - 0.002 18.0 2.4 0.32 10.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.13 KKK25799.1 - 0.0088 15.2 0.0 0.018 14.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_16 PF13191.6 KKK25799.1 - 0.009 16.4 0.2 0.024 15.0 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain ATPase PF06745.13 KKK25799.1 - 0.041 13.2 0.0 0.074 12.4 0.0 1.4 1 0 0 1 1 1 0 KaiC Oxysterol_BP PF01237.18 KKK25799.1 - 0.055 12.3 3.8 0.094 11.5 3.8 1.3 1 0 0 1 1 1 0 Oxysterol-binding protein AAA_25 PF13481.6 KKK25799.1 - 0.056 13.0 0.0 0.12 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KKK25799.1 - 0.075 13.6 0.0 0.23 12.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 KKK25799.1 - 0.087 12.8 0.0 0.23 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KKK25799.1 - 0.2 11.4 0.0 0.4 10.4 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain U1snRNP70_N PF12220.8 KKK25799.1 - 0.46 11.2 5.7 1.2 9.8 5.7 1.7 1 0 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RNA_pol_Rpc4 PF05132.14 KKK25799.1 - 7.4 7.0 11.7 1e+02 3.3 10.1 2.3 2 0 0 2 2 2 0 RNA polymerase III RPC4 Actin PF00022.19 KKK25800.1 - 1.2e-19 70.2 0.0 4.4e-13 48.6 0.0 3.3 3 1 0 3 3 3 3 Actin XPG_I PF00867.18 KKK25801.1 - 6.3e-24 84.2 0.0 1.6e-23 82.9 0.0 1.8 1 0 0 1 1 1 1 XPG I-region GEN1_C PF18380.1 KKK25801.1 - 4.9e-23 82.0 0.0 4.9e-23 82.0 0.0 2.6 2 1 0 2 2 2 1 Holliday junction resolvase Gen1 C-terminal domain XPG_N PF00752.17 KKK25801.1 - 2.2e-07 31.2 0.0 5.6e-07 30.0 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.7 KKK25801.1 - 0.12 11.8 0.0 0.28 10.6 0.0 1.5 1 0 0 1 1 1 0 XPG domain containing Mu-transpos_C PF09299.11 KKK25801.1 - 0.15 12.0 0.0 0.33 10.9 0.0 1.5 1 0 0 1 1 1 0 Mu transposase, C-terminal Gag_p12 PF01141.18 KKK25801.1 - 8.6 6.8 9.4 1.1 9.6 0.3 3.2 3 0 0 3 3 3 0 Gag polyprotein, inner coat protein p12 CFEM PF05730.11 KKK25802.1 - 0.00014 21.9 5.1 0.00014 21.9 5.1 3.3 3 0 0 3 3 3 1 CFEM domain Tme5_EGF_like PF09064.10 KKK25802.1 - 0.022 14.6 1.9 0.093 12.6 1.9 2.1 1 0 0 1 1 1 0 Thrombomodulin like fifth domain, EGF-like MFS_1 PF07690.16 KKK25804.1 - 6.5e-21 74.6 58.3 1.8e-19 69.9 58.3 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KKK25804.1 - 2.3e-10 39.9 13.5 2.3e-10 39.9 13.5 2.9 3 1 1 4 4 4 1 Sugar (and other) transporter OATP PF03137.20 KKK25804.1 - 4.8 5.4 12.3 0.021 13.1 2.3 2.0 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family DUF2852 PF11014.8 KKK25805.1 - 0.0021 18.2 2.8 0.85 9.8 0.5 2.6 2 1 0 2 2 2 2 Protein of unknown function (DUF2852) MLANA PF14991.6 KKK25805.1 - 0.027 14.7 1.7 6.2 7.1 0.0 2.9 2 1 0 2 2 2 0 Protein melan-A ADH_zinc_N PF00107.26 KKK25807.1 - 3.6e-18 65.8 0.0 5.4e-18 65.2 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KKK25807.1 - 1.8e-10 42.0 0.0 3.2e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 KKK25807.1 - 5.2e-07 29.5 0.0 5.8e-06 26.2 0.0 2.3 1 1 0 1 1 1 1 N-terminal domain of oxidoreductase Zn_clus PF00172.18 KKK25808.1 - 2.1e-06 27.7 9.9 2.1e-06 27.7 9.9 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KKK25808.1 - 0.0037 16.3 0.2 0.0098 15.0 0.2 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain HSBP1 PF06825.12 KKK25808.1 - 0.29 11.0 2.8 0.3 11.0 1.2 1.8 2 0 0 2 2 2 0 Heat shock factor binding protein 1 p450 PF00067.22 KKK25809.1 - 5.9e-39 134.1 0.0 8e-39 133.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Aldose_epim PF01263.20 KKK25810.1 - 8.9e-50 169.7 0.0 1.2e-49 169.2 0.0 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase Fer2_4 PF13510.6 KKK25810.1 - 0.0069 16.4 0.0 0.91 9.6 0.0 2.4 2 0 0 2 2 2 2 2Fe-2S iron-sulfur cluster binding domain FXMR_C2 PF16098.5 KKK25810.1 - 0.08 13.4 0.0 0.13 12.7 0.0 1.3 1 0 0 1 1 1 0 Fragile X-related mental retardation protein C-terminal region 2 AT_hook PF02178.19 KKK25811.1 - 0.088 12.7 21.5 0.87 9.7 5.8 3.1 2 0 0 2 2 2 0 AT hook motif adh_short_C2 PF13561.6 KKK25813.1 - 2.4e-47 161.5 0.0 3.5e-47 160.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KKK25813.1 - 2.4e-39 134.8 0.0 3.3e-39 134.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.21 KKK25813.1 - 9e-06 25.3 0.0 1.2e-05 24.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KKK25813.1 - 1.9e-05 24.7 0.0 6.7e-05 22.9 0.0 2.0 1 1 0 1 1 1 1 KR domain DUF1776 PF08643.10 KKK25813.1 - 0.06 12.7 0.0 0.079 12.3 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) DDHD PF02862.17 KKK25821.1 - 4.7e-26 92.3 0.1 4.6e-23 82.6 0.0 2.8 2 1 0 2 2 2 1 DDHD domain Abhydrolase_6 PF12697.7 KKK25821.1 - 0.3 11.7 0.0 0.3 11.7 0.0 2.6 3 0 0 3 3 3 0 Alpha/beta hydrolase family DUF3140 PF11338.8 KKK25822.1 - 0.02 15.3 0.0 0.026 14.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3140) BCDHK_Adom3 PF10436.9 KKK25822.1 - 0.12 12.2 0.0 0.12 12.2 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase ADH_zinc_N PF00107.26 KKK25824.1 - 5.4e-25 87.9 0.2 5.4e-25 87.9 0.2 1.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KKK25824.1 - 5.5e-12 45.5 1.3 1.1e-11 44.6 1.3 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KKK25824.1 - 7.8e-10 39.9 0.1 2.1e-09 38.5 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase adh_short PF00106.25 KKK25824.1 - 0.068 12.6 1.5 0.19 11.2 0.4 2.3 2 1 0 2 2 2 0 short chain dehydrogenase Arf PF00025.21 KKK25825.1 - 9.9e-74 246.5 0.0 1.2e-73 246.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KKK25825.1 - 5.9e-14 52.3 0.0 7.9e-14 51.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 KKK25825.1 - 2.4e-12 46.6 0.0 4.2e-12 45.9 0.0 1.2 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 KKK25825.1 - 3e-10 39.8 0.2 4.5e-06 26.1 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 KKK25825.1 - 5.1e-10 39.2 0.0 6e-10 39.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 KKK25825.1 - 1.2e-08 34.6 0.0 1.6e-08 34.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KKK25825.1 - 2.7e-06 27.4 0.0 4.7e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KKK25825.1 - 0.00064 19.3 0.0 0.051 13.1 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 KKK25825.1 - 0.02 14.4 0.4 0.065 12.8 0.4 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_18 PF13238.6 KKK25825.1 - 0.087 13.4 0.1 0.18 12.3 0.0 1.5 1 1 0 1 1 1 0 AAA domain Paf1 PF03985.13 KKK25826.1 - 1.1e-55 189.4 0.0 1.1e-55 189.4 0.0 1.7 2 0 0 2 2 2 1 Paf1 Actin PF00022.19 KKK25826.1 - 1.2e-28 99.9 0.0 1.7e-17 63.2 0.0 2.4 2 0 0 2 2 2 2 Actin MreB_Mbl PF06723.13 KKK25826.1 - 0.00015 20.7 0.1 0.16 10.7 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein Actin_micro PF17003.5 KKK25826.1 - 0.00037 19.8 0.4 0.0061 15.8 0.1 2.5 3 0 0 3 3 3 1 Putative actin-like family FtsA PF14450.6 KKK25826.1 - 0.014 15.8 0.0 0.039 14.4 0.0 1.9 2 0 0 2 2 2 0 Cell division protein FtsA DUF2114 PF09887.9 KKK25826.1 - 0.19 10.2 0.1 0.27 9.7 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2114) TAT_ubiq PF07706.12 KKK25826.1 - 0.19 11.9 0.3 37 4.6 0.0 3.2 3 0 0 3 3 3 0 Aminotransferase ubiquitination site DUF3419 PF11899.8 KKK25827.1 - 7.5e-159 529.0 0.0 9.7e-159 528.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_23 PF13489.6 KKK25827.1 - 6.6e-13 48.8 0.0 2e-11 44.0 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KKK25827.1 - 1.1e-08 35.6 0.0 4.5e-08 33.7 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKK25827.1 - 5.5e-08 33.4 0.0 8.1e-07 29.7 0.0 2.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KKK25827.1 - 3.2e-06 27.0 0.0 1.6e-05 24.7 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KKK25827.1 - 4.3e-06 27.3 0.0 0.00014 22.5 0.0 3.1 2 1 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 KKK25827.1 - 9.7e-06 25.1 0.0 4.2e-05 23.0 0.0 1.9 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family PCMT PF01135.19 KKK25827.1 - 0.00019 21.3 0.0 0.00036 20.3 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_2 PF00891.18 KKK25827.1 - 0.029 13.7 0.0 0.062 12.6 0.0 1.5 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_32 PF13679.6 KKK25827.1 - 0.08 12.9 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Glyco_hydro_17 PF00332.18 KKK25864.1 - 9.8e-10 38.5 5.1 1.4e-06 28.1 1.6 2.2 1 1 1 2 2 2 2 Glycosyl hydrolases family 17 rRNA_proc-arch PF13234.6 KKK25865.1 - 6e-85 285.4 1.4 1e-84 284.7 0.0 2.1 3 0 0 3 3 3 1 rRNA-processing arch domain DSHCT PF08148.12 KKK25865.1 - 8.7e-55 184.8 4.5 3.7e-54 182.8 3.3 2.3 2 0 0 2 2 2 1 DSHCT (NUC185) domain DEAD PF00270.29 KKK25865.1 - 3.5e-18 66.0 0.2 2.5e-17 63.2 0.0 2.5 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KKK25865.1 - 3.6e-06 27.3 0.0 1.2e-05 25.6 0.0 2.0 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KKK25865.1 - 7.9e-05 22.7 0.0 0.00021 21.4 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit T2SSE PF00437.20 KKK25865.1 - 0.014 14.5 0.0 0.064 12.3 0.0 2.0 2 0 0 2 2 2 0 Type II/IV secretion system protein Prp19 PF08606.11 KKK25865.1 - 0.026 14.5 0.4 1.5 8.9 0.2 2.8 2 0 0 2 2 2 0 Prp19/Pso4-like ATPase_2 PF01637.18 KKK25865.1 - 0.075 12.9 0.1 0.27 11.1 0.0 2.0 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_22 PF13401.6 KKK25865.1 - 0.097 12.9 0.0 0.42 10.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUF5388 PF17363.2 KKK25865.1 - 0.18 12.0 0.6 1.1 9.5 0.1 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5388) COX7C PF02935.16 KKK25866.1 - 8.5e-19 67.6 6.0 8.5e-19 67.6 6.0 1.7 2 0 0 2 2 2 1 Cytochrome c oxidase subunit VIIc IKI3 PF04762.12 KKK25867.1 - 2.6e-294 978.9 0.0 7.7e-294 977.3 0.0 1.6 1 1 0 1 1 1 1 IKI3 family Gmad1 PF10647.9 KKK25867.1 - 0.022 14.5 0.0 13 5.4 0.0 3.0 2 1 1 3 3 3 0 Lipoprotein LpqB beta-propeller domain BTAD PF03704.17 KKK25867.1 - 0.025 15.0 1.0 0.05 14.0 1.0 1.4 1 0 0 1 1 1 0 Bacterial transcriptional activator domain Pyr_redox_dim PF02852.22 KKK25868.1 - 7.2e-34 116.4 0.1 8.4e-34 116.1 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain DSPc PF00782.20 KKK25869.1 - 1.2e-24 86.6 0.0 1.6e-24 86.2 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 KKK25869.1 - 0.0014 18.9 0.0 0.0029 17.9 0.0 1.5 1 0 0 1 1 1 1 Rit1 DUSP-like domain Y_phosphatase PF00102.27 KKK25869.1 - 0.0029 17.2 0.0 0.0047 16.5 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase IBR PF01485.21 KKK25869.1 - 0.16 12.3 3.6 1.4 9.2 0.6 2.5 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain PTPlike_phytase PF14566.6 KKK25869.1 - 0.18 11.9 0.0 0.3 11.2 0.0 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate TFIID_20kDa PF03847.13 KKK25870.1 - 1.7e-21 76.5 0.0 3.5e-21 75.5 0.0 1.6 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Histone PF00125.24 KKK25870.1 - 0.0093 16.3 0.0 0.0093 16.3 0.0 2.7 3 0 0 3 3 3 1 Core histone H2A/H2B/H3/H4 DASH_Spc34 PF08657.10 KKK25871.1 - 1.6e-40 139.5 7.3 3.1e-21 76.3 0.1 2.1 1 1 1 2 2 2 2 DASH complex subunit Spc34 IL13 PF03487.13 KKK25871.1 - 0.028 14.2 1.9 0.036 13.8 0.2 1.9 2 0 0 2 2 2 0 Interleukin-13 DUF3866 PF12982.7 KKK25871.1 - 0.067 12.3 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3866) REV PF00424.18 KKK25871.1 - 0.095 12.7 0.1 0.28 11.2 0.1 1.8 1 0 0 1 1 1 0 REV protein (anti-repression trans-activator protein) DUF3381 PF11861.8 KKK25871.1 - 0.16 11.8 3.3 0.97 9.2 0.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) Rotamase PF00639.21 KKK25871.1 - 0.25 12.3 2.0 1.2 10.1 0.1 2.2 2 0 0 2 2 2 0 PPIC-type PPIASE domain Rpn3_C PF08375.11 KKK25872.1 - 1.7e-25 89.2 0.6 5.8e-25 87.5 0.6 2.0 1 0 0 1 1 1 1 Proteasome regulatory subunit C-terminal PCI PF01399.27 KKK25872.1 - 1e-19 71.0 0.8 6.4e-19 68.4 0.0 2.5 3 0 0 3 3 3 1 PCI domain SWI-SNF_Ssr4 PF08549.10 KKK25872.1 - 2 6.9 14.2 4 6.0 14.2 1.4 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) polyprenyl_synt PF00348.17 KKK25873.1 - 2.6e-71 239.7 0.0 4.3e-71 239.0 0.0 1.4 1 0 0 1 1 1 1 Polyprenyl synthetase PH_11 PF15413.6 KKK25873.1 - 0.028 14.8 0.0 0.22 11.9 0.0 2.4 2 0 0 2 2 2 0 Pleckstrin homology domain MMM1 PF10296.9 KKK25873.1 - 0.034 13.2 0.0 0.066 12.3 0.0 1.4 1 0 0 1 1 1 0 Maintenance of mitochondrial morphology protein 1 ANTH PF07651.16 KKK25874.1 - 4.1e-74 249.0 0.0 4.1e-74 249.0 0.0 3.2 2 1 0 3 3 3 1 ANTH domain I_LWEQ PF01608.17 KKK25874.1 - 4.8e-56 189.3 9.9 4.8e-56 189.3 9.9 5.9 3 2 1 5 5 5 2 I/LWEQ domain DEAD PF00270.29 KKK25892.1 - 7.3e-38 130.1 0.0 2.5e-37 128.3 0.0 1.9 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KKK25892.1 - 7.4e-22 77.8 0.0 1.5e-21 76.8 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 KKK25892.1 - 3.4e-21 75.2 0.0 6.4e-21 74.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) AAA_22 PF13401.6 KKK25892.1 - 0.012 15.9 0.1 0.42 10.9 0.0 3.0 3 0 0 3 3 3 0 AAA domain ResIII PF04851.15 KKK25892.1 - 0.055 13.5 0.0 0.24 11.4 0.0 2.0 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit DUF1289 PF06945.13 KKK25892.1 - 0.086 12.7 1.6 0.3 10.9 1.6 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1289) UvrD-helicase PF00580.21 KKK25892.1 - 0.11 12.0 3.1 3.7 7.0 0.0 2.2 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain DUF3984 PF13136.6 KKK25893.1 - 4.2 6.7 14.1 4.2 6.7 12.3 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3984) GFO_IDH_MocA PF01408.22 KKK25915.1 - 9.4e-11 42.6 0.0 2.3e-10 41.4 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold SRP72 PF08492.12 KKK25916.1 - 1e-16 61.1 4.0 1e-16 61.1 4.0 2.5 2 0 0 2 2 2 1 SRP72 RNA-binding domain SRP_TPR_like PF17004.5 KKK25916.1 - 4.2e-13 49.3 0.4 2.5e-12 46.9 0.1 2.4 2 0 0 2 2 2 1 Putative TPR-like repeat TPR_19 PF14559.6 KKK25916.1 - 2.9e-08 34.1 11.2 0.0057 17.1 0.0 6.8 5 2 2 7 7 7 2 Tetratricopeptide repeat TPR_14 PF13428.6 KKK25916.1 - 1.6e-05 25.3 10.4 14 6.9 0.0 8.4 7 2 3 10 10 9 0 Tetratricopeptide repeat TPR_2 PF07719.17 KKK25916.1 - 0.00017 21.5 2.4 21 5.6 0.0 6.0 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_4 PF07721.14 KKK25916.1 - 0.0033 17.9 2.9 14 6.7 0.0 5.5 6 0 0 6 6 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 KKK25916.1 - 0.0069 16.2 0.5 25 4.9 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 KKK25916.1 - 0.0085 16.2 2.8 2.5 8.5 0.0 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat BTAD PF03704.17 KKK25916.1 - 0.0091 16.4 5.3 0.062 13.7 0.3 3.6 3 0 0 3 3 3 1 Bacterial transcriptional activator domain DUF4810 PF16068.5 KKK25916.1 - 0.018 15.5 0.4 0.24 11.9 0.0 3.1 3 0 0 3 3 2 0 Domain of unknown function (DUF4810) SPO22 PF08631.10 KKK25916.1 - 0.052 13.0 1.2 0.14 11.6 1.2 1.7 1 1 0 1 1 1 0 Meiosis protein SPO22/ZIP4 like TPR_20 PF14561.6 KKK25916.1 - 0.062 13.6 1.6 0.31 11.4 0.0 3.0 3 0 0 3 3 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KKK25916.1 - 0.067 13.4 9.2 8.6 6.7 0.1 5.4 6 1 0 6 6 6 0 Anaphase-promoting complex, cyclosome, subunit 3 PPR PF01535.20 KKK25916.1 - 0.31 11.4 6.1 37 4.9 0.0 5.4 6 0 0 6 6 6 0 PPR repeat Glyco_hydro_31 PF01055.26 KKK25917.1 - 1.5e-149 498.9 1.8 2.1e-149 498.5 1.8 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 KKK25917.1 - 2e-32 111.8 0.0 3.7e-32 111.0 0.0 1.5 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Rotavirus_VP7 PF05868.11 KKK25917.1 - 0.0019 17.7 0.2 0.0034 16.8 0.2 1.3 1 0 0 1 1 1 1 Rotavirus major outer capsid protein VP7 Gal_mutarotas_2 PF13802.6 KKK25917.1 - 0.08 13.3 0.6 0.39 11.1 0.2 2.4 2 0 0 2 2 2 0 Galactose mutarotase-like HNH_2 PF13391.6 KKK25918.1 - 1.8e-06 28.0 0.1 4.1e-06 26.8 0.1 1.6 1 0 0 1 1 1 1 HNH endonuclease Fringe PF02434.16 KKK25919.1 - 3.2e-09 36.6 0.0 1.2e-08 34.7 0.0 1.8 1 1 0 1 1 1 1 Fringe-like DUF604 PF04646.12 KKK25919.1 - 2.8e-07 30.2 0.0 4.8e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF604 Homez PF11569.8 KKK25919.1 - 0.14 11.7 0.0 2 7.9 0.0 2.4 2 0 0 2 2 2 0 Homeodomain leucine-zipper encoding, Homez Fungal_trans PF04082.18 KKK25920.1 - 1.6e-11 43.7 0.3 3.7e-11 42.6 0.3 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK25920.1 - 6e-09 35.9 11.6 1.5e-08 34.6 11.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain vWA-TerF-like PF10138.9 KKK25921.1 - 8.1e-06 26.1 0.0 1.2e-05 25.5 0.0 1.2 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA PF00092.28 KKK25921.1 - 0.17 12.2 0.0 1.1 9.5 0.0 2.0 1 1 0 1 1 1 0 von Willebrand factor type A domain DPPIV_N PF00930.21 KKK25922.1 - 2e-117 391.9 0.0 2.6e-117 391.5 0.0 1.1 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 KKK25922.1 - 4.1e-52 176.7 3.2 6.1e-52 176.2 3.2 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.20 KKK25922.1 - 0.00015 21.5 0.2 0.0004 20.1 0.2 1.6 1 1 0 1 1 1 1 Putative esterase Peptidase_S15 PF02129.18 KKK25922.1 - 0.00053 19.7 3.8 0.0021 17.7 1.6 2.2 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) PAF-AH_p_II PF03403.13 KKK25922.1 - 0.00078 18.1 0.0 0.3 9.5 0.0 2.2 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_1 PF00561.20 KKK25922.1 - 0.003 17.2 0.6 0.018 14.7 0.1 2.2 1 1 1 2 2 2 1 alpha/beta hydrolase fold DLH PF01738.18 KKK25922.1 - 0.07 12.7 0.0 0.21 11.1 0.0 1.7 1 1 0 1 1 1 0 Dienelactone hydrolase family AXE1 PF05448.12 KKK25922.1 - 0.13 10.9 0.4 0.43 9.2 0.1 1.9 2 1 0 2 2 2 0 Acetyl xylan esterase (AXE1) DUF3395 PF11875.8 KKK25930.1 - 2.9e-43 147.5 0.4 2.9e-43 147.5 0.4 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3395) RNase_H2_suC PF08615.11 KKK25930.1 - 0.093 12.9 0.3 1.4 9.1 0.1 2.3 2 0 0 2 2 2 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) CDC45 PF02724.14 KKK25930.1 - 0.75 8.0 10.4 0.073 11.4 2.0 2.2 2 0 0 2 2 2 0 CDC45-like protein Radial_spoke PF04712.12 KKK25930.1 - 4.5 6.1 9.6 3.3 6.5 0.3 2.2 2 0 0 2 2 2 0 Radial spokehead-like protein eIF-3c_N PF05470.12 KKK25930.1 - 8.1 4.6 6.8 13 4.0 3.1 2.0 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus SKIP_SNW PF02731.15 KKK25931.1 - 1.2e-72 242.9 4.9 1.2e-72 242.9 4.9 2.2 2 0 0 2 2 2 1 SKIP/SNW domain Ras PF00071.22 KKK25932.1 - 8.1e-36 123.1 0.0 9.3e-36 122.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KKK25932.1 - 3.7e-13 49.8 0.0 7.9e-13 48.7 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase ADH_zinc_N PF00107.26 KKK25932.1 - 0.056 13.4 0.0 9.5 6.2 0.0 2.2 2 0 0 2 2 2 0 Zinc-binding dehydrogenase NST1 PF13945.6 KKK25933.1 - 1.9e-72 243.4 0.7 1.9e-72 243.4 0.7 4.1 3 1 1 4 4 4 1 Salt tolerance down-regulator ketoacyl-synt PF00109.26 KKK25964.1 - 1.8e-66 224.3 0.0 3.8e-66 223.3 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 KKK25964.1 - 2.5e-63 213.2 0.3 5.2e-63 212.2 0.3 1.6 1 0 0 1 1 1 1 KR domain PS-DH PF14765.6 KKK25964.1 - 1.5e-59 201.7 0.0 2.4e-59 201.0 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 KKK25964.1 - 6.6e-51 173.7 0.5 3.1e-50 171.5 0.0 2.2 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KKK25964.1 - 9.9e-39 132.0 0.0 2.6e-38 130.7 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 KKK25964.1 - 9e-16 58.3 0.0 2.6e-15 56.8 0.0 1.9 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension adh_short PF00106.25 KKK25964.1 - 1.3e-13 50.9 0.1 4.3e-13 49.1 0.1 1.9 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KKK25964.1 - 1.1e-10 41.5 0.1 2.8e-10 40.1 0.1 1.7 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Methyltransf_31 PF13847.6 KKK25964.1 - 1.7e-07 31.2 0.0 4.7e-07 29.7 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.26 KKK25964.1 - 5e-07 29.8 0.0 1.7e-06 28.0 0.0 2.0 2 0 0 2 2 1 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.6 KKK25964.1 - 7.3e-07 29.2 0.0 2e-06 27.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.25 KKK25964.1 - 6.8e-05 23.1 0.0 0.00021 21.6 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_12 PF08242.12 KKK25964.1 - 0.00021 21.9 0.0 0.00067 20.4 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.23 KKK25964.1 - 0.00043 19.7 0.1 0.00094 18.6 0.1 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_11 PF08241.12 KKK25964.1 - 0.00078 20.0 0.0 0.0032 18.1 0.0 2.2 2 0 0 2 2 1 1 Methyltransferase domain SAT PF16073.5 KKK25964.1 - 0.003 17.3 0.4 0.0072 16.1 0.4 1.6 1 0 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis ADH_N PF08240.12 KKK25964.1 - 0.0055 16.6 0.0 0.018 14.9 0.0 1.9 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Ubie_methyltran PF01209.18 KKK25964.1 - 0.0077 15.6 0.0 0.015 14.7 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 KKK25964.1 - 0.0084 16.8 0.0 0.049 14.3 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_16 PF10294.9 KKK25964.1 - 0.034 13.9 0.0 0.11 12.2 0.0 1.8 2 0 0 2 2 2 0 Lysine methyltransferase GDP_Man_Dehyd PF16363.5 KKK25964.1 - 0.085 12.2 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase ABC2_membrane PF01061.24 KKK25965.1 - 4.2e-85 284.4 44.5 1.2e-47 162.1 18.2 2.5 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 KKK25965.1 - 8.4e-39 133.2 0.0 2.4e-18 67.0 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 KKK25965.1 - 1.3e-28 98.7 6.5 8.7e-27 92.9 0.0 3.6 3 0 0 3 3 3 2 CDR ABC transporter ABC_trans_N PF14510.6 KKK25965.1 - 6.4e-06 26.7 0.2 1.5e-05 25.5 0.2 1.6 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_16 PF13191.6 KKK25965.1 - 6.8e-06 26.6 0.1 0.0099 16.3 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 KKK25965.1 - 8.4e-05 22.9 0.0 0.95 9.7 0.0 3.1 2 0 0 2 2 2 2 AAA domain ABC2_membrane_3 PF12698.7 KKK25965.1 - 0.00017 20.8 37.4 0.021 13.9 17.4 2.5 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_25 PF13481.6 KKK25965.1 - 0.00069 19.3 0.1 0.025 14.1 0.1 2.3 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KKK25965.1 - 0.00073 19.2 0.4 0.09 12.5 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_33 PF13671.6 KKK25965.1 - 0.00075 19.7 0.0 1.2 9.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 KKK25965.1 - 0.001 19.0 0.0 0.016 15.1 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_28 PF13521.6 KKK25965.1 - 0.0016 18.7 0.4 0.98 9.7 0.4 2.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KKK25965.1 - 0.0018 18.8 0.0 2 9.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain PduV-EutP PF10662.9 KKK25965.1 - 0.0035 17.1 0.7 1.3 8.7 0.0 2.4 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation cobW PF02492.19 KKK25965.1 - 0.012 15.2 1.7 1.8 8.1 0.4 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.6 KKK25965.1 - 0.032 14.7 0.3 2.5 8.5 0.0 2.8 3 0 0 3 3 2 0 AAA domain NACHT PF05729.12 KKK25965.1 - 0.041 13.8 1.2 3.7 7.5 0.1 2.4 2 0 0 2 2 2 0 NACHT domain AAA PF00004.29 KKK25965.1 - 0.09 13.2 0.1 14 6.1 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 KKK25965.1 - 0.099 12.4 0.4 6 6.5 0.2 2.3 2 0 0 2 2 2 0 AAA domain ThrE PF06738.12 KKK25966.1 - 1.4e-76 257.0 15.9 3.8e-69 232.7 2.9 2.4 2 0 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 KKK25966.1 - 3e-13 50.0 10.9 3e-13 50.0 10.9 2.8 3 1 0 3 3 3 1 Threonine/Serine exporter, ThrE Lipase_2 PF01674.18 KKK25967.1 - 5.7e-08 32.5 0.1 1.5e-07 31.2 0.1 1.8 1 1 0 1 1 1 1 Lipase (class 2) Abhydrolase_1 PF00561.20 KKK25967.1 - 5.2e-06 26.3 0.3 2.1e-05 24.3 0.3 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KKK25967.1 - 1e-05 26.2 1.0 2.2e-05 25.2 1.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Palm_thioest PF02089.15 KKK25967.1 - 0.0047 16.8 0.0 0.014 15.3 0.0 1.7 1 1 0 1 1 1 1 Palmitoyl protein thioesterase DUF1749 PF08538.10 KKK25967.1 - 0.0075 15.4 0.0 0.011 14.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_2 PF02230.16 KKK25967.1 - 0.014 15.2 0.0 0.14 11.9 0.0 2.0 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase DUF900 PF05990.12 KKK25967.1 - 0.023 14.2 0.0 0.086 12.3 0.0 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) Hydrolase_4 PF12146.8 KKK25967.1 - 0.059 12.6 0.1 0.085 12.1 0.1 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 PGAP1 PF07819.13 KKK25967.1 - 0.064 13.0 1.0 0.18 11.5 0.0 2.0 2 1 0 3 3 3 0 PGAP1-like protein DUF676 PF05057.14 KKK25967.1 - 0.079 12.4 0.0 0.17 11.4 0.0 1.4 1 1 0 1 1 1 0 Putative serine esterase (DUF676) MFS_1 PF07690.16 KKK25968.1 - 1.7e-15 56.8 49.7 5.6e-11 42.0 33.1 2.4 2 1 0 3 3 3 2 Major Facilitator Superfamily GFA PF04828.14 KKK25969.1 - 5.5e-22 77.9 1.0 7.3e-22 77.5 1.0 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Aldolase_II PF00596.21 KKK25970.1 - 9.8e-50 169.1 0.1 1.2e-49 168.8 0.1 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain S-methyl_trans PF02574.16 KKK25971.1 - 4.7e-41 141.4 0.0 8.8e-41 140.5 0.0 1.4 1 0 0 1 1 1 1 Homocysteine S-methyltransferase LysM PF01476.20 KKK25971.1 - 3.6e-24 84.6 3.5 2e-09 37.4 0.0 5.3 5 0 0 5 5 5 4 LysM domain Glyco_hydro_18 PF00704.28 KKK25972.1 - 4.4e-68 230.3 2.7 4.4e-68 230.3 2.7 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 KKK25972.1 - 3.2e-09 37.1 11.1 3.2e-09 37.1 11.1 5.4 6 1 0 6 6 6 2 Chitin recognition protein Glyco_hydro_85 PF03644.13 KKK25972.1 - 0.02 14.3 0.0 0.033 13.6 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 85 UPF0113_N PF17833.1 KKK25974.1 - 4.7e-23 81.6 0.0 6.6e-23 81.1 0.0 1.2 1 0 0 1 1 1 1 UPF0113 Pre-PUA domain UPF0113 PF03657.13 KKK25974.1 - 1.6e-21 76.3 0.0 2.9e-21 75.5 0.0 1.4 1 0 0 1 1 1 1 UPF0113 PUA domain PUA PF01472.20 KKK25974.1 - 0.16 12.0 0.0 0.3 11.1 0.0 1.4 1 0 0 1 1 1 0 PUA domain TANGO2 PF05742.12 KKK25975.1 - 3e-63 214.2 0.0 3.4e-63 214.0 0.0 1.0 1 0 0 1 1 1 1 Transport and Golgi organisation 2 Fungal_trans_2 PF11951.8 KKK25976.1 - 2.2e-07 30.1 0.0 5.2e-07 28.8 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KKK25976.1 - 2.4e-05 24.4 12.6 2.4e-05 24.4 12.6 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribophorin_II PF05817.14 KKK25977.1 - 1.4e-27 96.5 0.0 2.1e-27 96.0 0.0 1.2 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II Ribosomal_60s PF00428.19 KKK25979.1 - 3.1 8.5 9.0 0.34 11.5 1.6 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein His_Phos_2 PF00328.22 KKK25980.1 - 1.9e-75 254.6 0.0 2.2e-75 254.4 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) HAMP PF00672.25 KKK25982.1 - 2.3e-44 149.5 14.5 4.3e-09 36.6 0.0 7.3 6 1 0 6 6 6 5 HAMP domain HATPase_c PF02518.26 KKK25982.1 - 3.4e-32 111.3 0.1 1.5e-31 109.2 0.1 2.2 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KKK25982.1 - 4.2e-27 94.5 0.6 2e-26 92.3 0.6 2.3 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 KKK25982.1 - 8.4e-17 61.0 3.5 3.1e-16 59.2 0.2 3.8 4 0 0 4 4 3 1 His Kinase A (phospho-acceptor) domain Syntaxin_2 PF14523.6 KKK25982.1 - 1e-05 25.9 21.8 1.2 9.6 0.1 7.2 3 2 2 6 6 6 2 Syntaxin-like protein DUF4279 PF14106.6 KKK25982.1 - 7.7e-05 22.9 0.0 7.8 6.7 0.0 5.3 5 1 0 5 5 5 1 Domain of unknown function (DUF4279) DUF1843 PF08898.10 KKK25982.1 - 0.00055 20.4 6.3 16 6.1 0.1 6.0 5 1 0 5 5 5 0 Domain of unknown function (DUF1843) DUF948 PF06103.11 KKK25982.1 - 0.007 16.6 58.5 1 9.6 0.3 10.2 4 2 3 7 7 7 4 Bacterial protein of unknown function (DUF948) SpoIIID PF12116.8 KKK25982.1 - 0.032 14.3 4.8 23 5.1 0.0 5.3 5 0 0 5 5 5 0 Stage III sporulation protein D Fib_alpha PF08702.10 KKK25982.1 - 0.04 14.1 37.4 1.2 9.4 0.6 7.4 6 1 1 7 7 7 0 Fibrinogen alpha/beta chain family NOD PF06816.13 KKK25982.1 - 0.049 13.3 0.0 6.4 6.5 0.0 2.7 2 0 0 2 2 2 0 NOTCH protein Cbl_N PF02262.16 KKK25982.1 - 0.074 13.1 0.5 5.2 7.1 0.3 3.1 3 0 0 3 3 3 0 CBL proto-oncogene N-terminal domain 1 IcmF_C PF06744.12 KKK25982.1 - 0.076 12.6 0.1 0.28 10.8 0.1 2.0 1 0 0 1 1 1 0 Type VI secretion protein IcmF C-terminal CMD PF02627.20 KKK25982.1 - 0.15 12.1 1.2 17 5.6 0.0 4.0 5 0 0 5 5 4 0 Carboxymuconolactone decarboxylase family DUF3829 PF12889.7 KKK25982.1 - 0.19 11.2 19.0 0.35 10.3 0.8 5.3 3 3 3 6 6 6 0 Protein of unknown function (DUF3829) BORCS6 PF10157.9 KKK25982.1 - 0.59 10.3 15.1 6 7.1 0.1 5.7 3 2 1 5 5 5 0 BLOC-1-related complex sub-unit 6 Gp-FAR-1 PF05823.12 KKK25982.1 - 0.77 10.1 12.1 14 6.0 0.2 5.1 2 1 2 6 6 5 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) DUF4795 PF16043.5 KKK25982.1 - 0.9 9.1 30.7 1.7 8.2 7.2 4.9 1 1 1 3 3 3 0 Domain of unknown function (DUF4795) WXG100 PF06013.12 KKK25982.1 - 1.5 9.1 32.5 2 8.7 0.3 8.4 7 3 2 9 9 9 0 Proteins of 100 residues with WXG Mer2 PF09074.10 KKK25982.1 - 3.5 7.4 39.2 3.3 7.5 3.6 6.1 3 1 2 5 5 5 0 Mer2 GLE1 PF07817.13 KKK25982.1 - 9.1 5.4 14.4 9.3 5.4 1.0 4.7 3 1 2 5 5 5 0 GLE1-like protein Aldo_ket_red PF00248.21 KKK25984.1 - 8.9e-64 215.5 0.0 1.1e-63 215.2 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family DUF4202 PF13875.6 KKK25986.1 - 2.2e-51 174.4 0.0 2.4e-51 174.3 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4202) Ribosomal_S25 PF03297.15 KKK25987.1 - 2.6e-28 98.2 1.0 4.9e-28 97.3 1.0 1.4 1 0 0 1 1 1 1 S25 ribosomal protein ANAPC4_WD40 PF12894.7 KKK25987.1 - 0.00094 19.4 0.2 4.5 7.6 0.0 3.7 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KKK25987.1 - 0.0097 16.8 1.3 8.2 7.5 0.2 4.5 3 1 1 4 4 4 1 WD domain, G-beta repeat MarR_2 PF12802.7 KKK25987.1 - 0.15 11.9 0.1 0.29 11.1 0.1 1.4 1 0 0 1 1 1 0 MarR family PD40 PF07676.12 KKK25987.1 - 0.39 10.7 2.6 0.79 9.7 0.1 2.8 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat TPR_1 PF00515.28 KKK25988.1 - 6.4e-37 123.9 23.5 2.1e-07 30.5 0.1 9.8 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_2 PF07719.17 KKK25988.1 - 2.4e-34 114.6 23.0 6.3e-05 22.8 0.0 10.4 10 0 0 10 10 10 7 Tetratricopeptide repeat ANAPC3 PF12895.7 KKK25988.1 - 5.2e-29 100.3 15.7 1.3e-23 83.0 0.4 4.4 3 1 2 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 KKK25988.1 - 4.3e-25 87.1 5.9 7.6e-06 25.5 0.7 8.9 7 2 2 9 9 9 7 TPR repeat TPR_19 PF14559.6 KKK25988.1 - 8.4e-22 77.5 18.3 3.6e-07 30.6 1.0 7.8 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_8 PF13181.6 KKK25988.1 - 1.3e-21 74.9 11.7 0.0083 16.3 0.0 9.9 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_12 PF13424.6 KKK25988.1 - 2.7e-19 69.2 9.7 0.0065 16.7 0.2 8.4 6 1 2 8 8 8 5 Tetratricopeptide repeat TPR_16 PF13432.6 KKK25988.1 - 5.5e-19 68.5 16.9 1.8e-05 25.3 0.2 7.8 7 1 1 8 8 8 5 Tetratricopeptide repeat TPR_14 PF13428.6 KKK25988.1 - 6.2e-16 57.7 12.7 0.14 13.1 0.0 9.4 6 1 3 9 9 9 3 Tetratricopeptide repeat TPR_17 PF13431.6 KKK25988.1 - 1.3e-09 37.8 16.6 0.27 11.7 0.0 8.2 9 1 1 10 10 9 4 Tetratricopeptide repeat TPR_7 PF13176.6 KKK25988.1 - 5.9e-08 32.2 7.4 0.33 11.1 0.0 7.0 7 1 0 7 7 6 2 Tetratricopeptide repeat TPR_6 PF13174.6 KKK25988.1 - 7.3e-05 23.2 17.6 8.1 7.3 0.2 9.0 11 0 0 11 11 9 1 Tetratricopeptide repeat TPR_9 PF13371.6 KKK25988.1 - 0.00037 20.6 5.1 3.4 7.9 0.3 5.4 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_10 PF13374.6 KKK25988.1 - 0.024 14.5 3.3 97 3.0 0.2 5.6 6 0 0 6 6 6 0 Tetratricopeptide repeat DUF410 PF04190.13 KKK25988.1 - 0.058 13.2 1.5 0.66 9.7 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF410) ChAPs PF09295.10 KKK25988.1 - 0.078 12.0 1.3 8.5 5.3 0.0 3.1 3 0 0 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) MIT PF04212.18 KKK25988.1 - 1.5 9.0 6.5 28 4.9 0.5 4.8 5 0 0 5 5 5 0 MIT (microtubule interacting and transport) domain Acyltransferase PF01553.21 KKK25989.1 - 1.5e-32 112.1 0.0 2.3e-32 111.5 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Apolipoprotein PF01442.18 KKK25990.1 - 4.3 7.2 9.8 15 5.4 7.4 3.0 2 1 1 3 3 3 0 Apolipoprotein A1/A4/E domain SKIP_SNW PF02731.15 KKK25990.1 - 9.9 5.8 6.8 6.6 6.4 0.8 2.7 3 0 0 3 3 3 0 SKIP/SNW domain TMEM208_SND2 PF05620.11 KKK25991.1 - 2.6e-54 183.5 0.0 2.9e-54 183.3 0.0 1.0 1 0 0 1 1 1 1 SRP-independent targeting protein 2/TMEM208 ACC_central PF08326.12 KKK25992.1 - 1.3e-266 886.5 0.0 1.8e-266 886.1 0.0 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.22 KKK25992.1 - 1.1e-191 637.8 0.0 2.2e-191 636.8 0.0 1.5 2 0 0 2 2 2 1 Carboxyl transferase domain CPSase_L_D2 PF02786.17 KKK25992.1 - 1.7e-51 174.7 0.0 6.4e-51 172.9 0.0 1.9 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 KKK25992.1 - 3.2e-28 98.5 0.1 6.1e-28 97.6 0.1 1.5 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 KKK25992.1 - 6.3e-23 80.9 0.0 1.5e-19 70.1 0.0 3.5 3 0 0 3 3 3 2 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 KKK25992.1 - 4.4e-17 61.7 0.1 1.2e-16 60.3 0.1 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_3 PF02655.14 KKK25992.1 - 0.0035 17.4 0.0 0.012 15.7 0.0 1.9 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 KKK25992.1 - 0.0046 16.5 0.0 0.011 15.3 0.0 1.7 2 0 0 2 2 2 1 D-ala D-ala ligase C-terminus GxGYxYP_N PF16216.5 KKK25992.1 - 0.052 13.7 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 GxGYxY sequence motif in domain of unknown function N-terminal ATPgrasp_Ter PF15632.6 KKK25992.1 - 0.16 11.7 0.0 0.39 10.5 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon RINGv PF12906.7 KKK25993.1 - 8.2e-15 54.7 9.3 1.6e-14 53.7 9.3 1.5 1 0 0 1 1 1 1 RING-variant domain HeLo PF14479.6 KKK25993.1 - 4.9e-07 29.8 0.3 4.6e-05 23.3 0.3 2.5 1 1 0 1 1 1 1 Prion-inhibition and propagation zf-RING_2 PF13639.6 KKK25993.1 - 0.0069 16.7 8.8 0.019 15.3 8.8 1.8 1 0 0 1 1 1 1 Ring finger domain zf-RING_4 PF14570.6 KKK25993.1 - 2.4 8.0 7.5 5 7.0 7.5 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Astro_capsid_p PF12226.8 KKK25993.1 - 9.8 5.2 8.5 16 4.5 8.5 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein NUDE_C PF04880.13 KKK25994.1 - 1.1e-68 231.2 2.6 1.1e-68 231.2 2.6 4.1 3 1 1 4 4 2 1 NUDE protein, C-terminal conserved region ZapB PF06005.12 KKK25994.1 - 6.5e-05 23.3 7.1 6.5e-05 23.3 7.1 4.7 2 1 3 5 5 5 1 Cell division protein ZapB BAR_2 PF10455.9 KKK25994.1 - 0.0022 17.2 7.7 0.004 16.3 7.7 1.4 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking TPR_MLP1_2 PF07926.12 KKK25994.1 - 0.0042 17.1 34.4 0.015 15.4 11.5 3.8 2 1 1 4 4 4 2 TPR/MLP1/MLP2-like protein PSII_Pbs27 PF13326.6 KKK25994.1 - 0.0056 17.0 5.7 0.013 15.8 5.7 1.6 1 0 0 1 1 1 1 Photosystem II Pbs27 AKNA PF12443.8 KKK25994.1 - 0.027 15.1 10.1 0.26 12.0 3.3 3.9 3 0 0 3 3 3 0 AT-hook-containing transcription factor Chibby PF14645.6 KKK25994.1 - 0.03 14.7 11.6 1.5 9.2 0.3 2.8 1 1 1 2 2 2 0 Chibby family LPP PF04728.13 KKK25994.1 - 0.03 14.7 7.2 0.084 13.3 0.4 3.8 4 1 0 4 4 3 0 Lipoprotein leucine-zipper Alanine_zipper PF11839.8 KKK25994.1 - 0.031 14.6 0.7 0.031 14.6 0.7 2.6 3 0 0 3 3 2 0 Alanine-zipper, major outer membrane lipoprotein SOGA PF11365.8 KKK25994.1 - 0.037 15.1 5.2 0.037 15.1 5.2 3.9 2 1 1 4 4 3 0 Protein SOGA Fez1 PF06818.15 KKK25994.1 - 0.11 12.9 25.2 1.6 9.1 10.4 2.9 2 1 1 3 3 3 0 Fez1 Tropomyosin_1 PF12718.7 KKK25994.1 - 0.12 12.5 32.7 0.29 11.3 21.2 3.4 2 1 1 3 3 3 0 Tropomyosin like DUF745 PF05335.13 KKK25994.1 - 0.38 10.4 13.0 0.88 9.3 13.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF745) DASH_Duo1 PF08651.10 KKK25994.1 - 0.4 10.5 4.4 2.2 8.1 0.3 3.4 4 0 0 4 4 4 0 DASH complex subunit Duo1 Spc7 PF08317.11 KKK25994.1 - 0.57 9.0 29.1 0.0086 15.0 19.4 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein XRN_M PF17846.1 KKK25994.1 - 0.63 8.9 4.3 1.2 8.0 4.3 1.4 1 0 0 1 1 1 0 Xrn1 helical domain CENP-F_leu_zip PF10473.9 KKK25994.1 - 0.64 10.0 30.0 0.53 10.3 23.6 2.9 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF812 PF05667.11 KKK25994.1 - 0.77 8.6 22.8 1.4 7.7 22.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF812) APG6_N PF17675.1 KKK25994.1 - 1.1 9.9 39.0 0.18 12.3 9.9 3.2 1 1 2 3 3 3 0 Apg6 coiled-coil region Cep57_MT_bd PF06657.13 KKK25994.1 - 1.1 9.7 22.3 1.5 9.3 0.9 3.8 2 1 2 4 4 4 0 Centrosome microtubule-binding domain of Cep57 YabA PF06156.13 KKK25994.1 - 1.8 9.3 21.2 0.18 12.5 3.1 3.0 2 1 2 4 4 3 0 Initiation control protein YabA Tho2 PF11262.8 KKK25994.1 - 1.8 7.7 20.9 0.18 11.0 3.3 2.2 1 1 1 2 2 2 0 Transcription factor/nuclear export subunit protein 2 STAT_alpha PF01017.20 KKK25994.1 - 1.9 8.4 12.3 2.7 7.9 5.4 2.7 2 1 0 3 3 3 0 STAT protein, all-alpha domain Filament PF00038.21 KKK25994.1 - 2.3 7.7 27.4 7.6 6.0 27.4 2.0 1 1 0 1 1 1 0 Intermediate filament protein DUF3584 PF12128.8 KKK25994.1 - 3.5 5.0 24.2 4.2 4.8 21.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) ADIP PF11559.8 KKK25994.1 - 3.7 7.6 29.9 1.9 8.6 2.3 3.8 2 1 2 4 4 3 0 Afadin- and alpha -actinin-Binding DUF2046 PF09755.9 KKK25994.1 - 4.3 6.5 25.1 0.12 11.6 13.9 2.9 2 1 1 3 3 3 0 Uncharacterized conserved protein H4 (DUF2046) DUF1664 PF07889.12 KKK25994.1 - 5.6 7.0 12.4 0.36 10.9 4.6 2.5 2 1 1 3 3 2 0 Protein of unknown function (DUF1664) Fmp27_WPPW PF10359.9 KKK25994.1 - 6 5.6 17.4 0.61 8.9 11.0 2.2 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain GAS PF13851.6 KKK25994.1 - 6 6.2 30.5 6.6 6.0 19.4 2.9 1 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding CCDC144C PF14915.6 KKK25994.1 - 7.2 5.6 28.1 50 2.9 28.1 2.1 1 1 0 1 1 1 0 CCDC144C protein coiled-coil region DMPK_coil PF08826.10 KKK25994.1 - 9.3 6.5 29.7 0.38 10.9 2.1 4.4 4 1 1 5 5 4 0 DMPK coiled coil domain like JIP_LZII PF16471.5 KKK25994.1 - 9.4 6.5 19.0 1.8 8.8 0.4 4.0 2 1 1 4 4 4 0 JNK-interacting protein leucine zipper II Cupin_2 PF07883.11 KKK25995.1 - 5.1e-11 42.1 0.0 4.2e-06 26.4 0.0 2.3 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 KKK25995.1 - 2.2e-05 24.1 0.0 0.0043 16.7 0.0 2.5 3 0 0 3 3 3 2 Protein of unknown function (DUF861) AraC_binding PF02311.19 KKK25995.1 - 0.00033 20.6 0.1 0.078 12.9 0.1 2.2 2 0 0 2 2 2 2 AraC-like ligand binding domain Cupin_6 PF12852.7 KKK25995.1 - 0.0033 17.2 0.0 0.0065 16.2 0.0 1.5 1 0 0 1 1 1 1 Cupin SprB PF13573.6 KKK25995.1 - 0.054 13.3 0.1 0.11 12.3 0.1 1.5 1 0 0 1 1 1 0 SprB repeat ADH_zinc_N PF00107.26 KKK25996.1 - 6.9e-16 58.4 0.0 9.9e-16 57.9 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 KKK25996.1 - 8.4e-09 35.3 0.0 1.8e-08 34.2 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 KKK25996.1 - 1.1e-07 32.9 0.0 1.8e-07 32.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase FMO-like PF00743.19 KKK25997.1 - 1e-15 57.2 0.0 2.9e-15 55.7 0.0 1.7 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 KKK25997.1 - 3.6e-08 33.5 0.0 9.8e-08 32.1 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KKK25997.1 - 0.00043 20.3 0.1 0.0012 18.8 0.0 1.8 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 KKK25997.1 - 0.0011 18.3 0.0 0.009 15.3 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KKK25997.1 - 0.0014 18.0 0.0 0.043 13.1 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 KKK25997.1 - 0.0056 16.1 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DAO PF01266.24 KKK25997.1 - 0.18 11.3 0.0 0.88 9.1 0.0 2.0 1 1 1 2 2 2 0 FAD dependent oxidoreductase Pyr_redox PF00070.27 KKK25997.1 - 0.23 12.0 0.0 3.5 8.3 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase p450 PF00067.22 KKK25998.1 - 3.1e-40 138.3 0.0 3.6e-40 138.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Abhydrolase_3 PF07859.13 KKK25999.1 - 1.3e-42 146.1 0.0 1.7e-42 145.7 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KKK25999.1 - 1.6e-06 27.3 0.1 8.8e-06 24.8 0.1 1.9 1 1 0 1 1 1 1 Carboxylesterase family Patatin PF01734.22 KKK25999.1 - 0.15 12.2 0.1 0.29 11.3 0.0 1.5 2 0 0 2 2 2 0 Patatin-like phospholipase ADH_N PF08240.12 KKK26000.1 - 1.5e-29 102.0 1.1 8.4e-29 99.7 0.0 2.5 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KKK26000.1 - 2.6e-21 76.0 0.1 4.4e-21 75.2 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KKK26000.1 - 1.2e-06 28.2 0.1 2.3e-06 27.3 0.1 1.5 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 KKK26000.1 - 0.00012 23.1 0.1 0.00079 20.5 0.0 2.3 2 1 0 2 2 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KKK26000.1 - 0.0015 17.8 0.6 0.0023 17.3 0.6 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_2 PF07992.14 KKK26000.1 - 0.0035 16.6 0.0 0.0052 16.1 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KKK26000.1 - 0.0038 16.0 0.2 0.0054 15.5 0.2 1.2 1 0 0 1 1 1 1 HI0933-like protein AdoHcyase_NAD PF00670.21 KKK26000.1 - 0.0055 16.8 0.4 0.16 12.1 0.4 2.2 2 0 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Pyr_redox PF00070.27 KKK26000.1 - 0.0084 16.7 0.0 0.045 14.3 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 KKK26000.1 - 0.16 11.3 0.0 0.28 10.5 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.6 KKK26000.1 - 0.17 11.1 0.1 0.3 10.3 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Aldo_ket_red PF00248.21 KKK26001.1 - 6e-47 160.3 0.1 5.6e-45 153.8 0.1 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family DLH PF01738.18 KKK26002.1 - 1.1e-21 77.4 0.0 1.4e-21 77.1 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family DUF915 PF06028.11 KKK26002.1 - 0.024 13.9 0.0 0.033 13.5 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) LIM_bind PF01803.16 KKK26003.1 - 5.5e-70 235.6 0.7 5.5e-70 235.6 0.7 4.7 3 1 1 4 4 4 1 LIM-domain binding protein TAL_FSA PF00923.19 KKK26004.1 - 9.3e-76 254.9 0.0 1.1e-75 254.7 0.0 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase Chorismate_synt PF01264.21 KKK26004.1 - 0.13 10.9 0.0 0.2 10.3 0.0 1.2 1 0 0 1 1 1 0 Chorismate synthase AA_permease_2 PF13520.6 KKK26005.1 - 1.8e-53 181.9 53.0 2.1e-53 181.7 53.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KKK26005.1 - 1.8e-19 69.7 47.2 2.6e-19 69.2 47.2 1.1 1 0 0 1 1 1 1 Amino acid permease Aldedh PF00171.22 KKK26006.1 - 7e-163 542.4 0.1 7.8e-163 542.2 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 KKK26006.1 - 0.034 13.6 0.1 0.4 10.1 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1487) MFS_1 PF07690.16 KKK26007.1 - 1e-42 146.4 44.5 1e-42 146.4 44.5 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KKK26007.1 - 7.4e-09 34.6 21.3 1.1e-08 34.1 21.3 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF5337 PF17272.2 KKK26007.1 - 0.86 9.5 7.3 3.3 7.6 1.8 2.9 2 0 0 2 2 2 0 Family of unknown function (DUF5337) Orai-1 PF07856.12 KKK26007.1 - 2 8.0 6.0 0.6 9.8 0.9 2.6 3 0 0 3 3 3 0 Mediator of CRAC channel activity OATP PF03137.20 KKK26007.1 - 3.3 5.9 16.9 3.5e+02 -0.8 16.4 2.6 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DUF726 PF05277.12 KKK26008.1 - 3.4e-119 397.8 0.5 4.4e-119 397.4 0.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) CPP1-like PF11833.8 KKK26008.1 - 0.054 13.1 0.0 0.15 11.7 0.0 1.8 1 0 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like RIBIOP_C PF04950.12 KKK26009.1 - 2.5e-109 365.2 0.0 4.6e-109 364.4 0.0 1.4 1 0 0 1 1 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 KKK26009.1 - 1.7e-21 76.1 0.0 4.1e-21 74.9 0.0 1.7 1 0 0 1 1 1 1 AARP2CN (NUC121) domain BING4CT PF08149.11 KKK26010.1 - 1.9e-37 126.9 0.0 3e-35 119.9 0.0 2.8 2 0 0 2 2 2 2 BING4CT (NUC141) domain ANAPC4_WD40 PF12894.7 KKK26010.1 - 2.8e-08 33.9 0.2 1.9 8.8 0.0 5.9 3 2 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KKK26010.1 - 0.0014 19.5 0.3 9.6 7.3 0.0 4.6 5 0 0 5 5 5 1 WD domain, G-beta repeat Coatomer_WDAD PF04053.14 KKK26010.1 - 0.0063 15.6 0.0 0.011 14.8 0.0 1.3 1 0 0 1 1 1 1 Coatomer WD associated region Zn_clus PF00172.18 KKK26011.1 - 2e-05 24.6 12.3 2e-05 24.6 12.3 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SUIM_assoc PF16619.5 KKK26011.1 - 0.39 10.8 7.2 1.2 9.3 7.2 1.8 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 p450 PF00067.22 KKK26012.1 - 1.2e-34 119.9 0.0 1.6e-34 119.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 AA_permease_2 PF13520.6 KKK26013.1 - 1.7e-50 172.1 47.4 3.3e-45 154.7 30.7 2.0 1 1 1 2 2 2 2 Amino acid permease AA_permease PF00324.21 KKK26013.1 - 1.7e-22 79.7 43.4 1.5e-21 76.6 43.4 1.9 1 1 0 1 1 1 1 Amino acid permease DUF4282 PF14110.6 KKK26013.1 - 0.1 13.4 0.2 0.1 13.4 0.2 5.1 4 1 0 4 4 4 0 Domain of unknown function (DUF4282) Nodulin_late PF07127.11 KKK26013.1 - 8.6 6.8 6.7 0.79 10.1 1.3 2.2 2 0 0 2 2 2 0 Late nodulin protein Glu-tRNAGln PF02686.15 KKK26014.1 - 8.1e-13 48.5 0.1 7.4e-12 45.4 0.1 2.2 1 1 0 1 1 1 1 Glu-tRNAGln amidotransferase C subunit SNAP PF14938.6 KKK26015.1 - 1.9e-114 381.8 14.6 2.2e-114 381.7 14.6 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.6 KKK26015.1 - 1.1e-07 32.0 14.5 0.00096 19.4 0.3 4.1 3 2 0 3 3 3 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KKK26015.1 - 3.9e-05 23.2 5.4 0.00013 21.5 1.6 2.2 1 1 1 2 2 2 1 MalT-like TPR region TPR_7 PF13176.6 KKK26015.1 - 4.4e-05 23.2 7.9 4.1 7.7 0.2 4.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_6 PF13174.6 KKK26015.1 - 0.00016 22.1 13.9 1.4 9.7 0.1 6.2 6 1 0 6 6 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 KKK26015.1 - 0.0011 19.0 12.5 0.59 10.5 0.3 4.8 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 KKK26015.1 - 0.0032 17.4 22.4 3.7 7.9 2.0 6.7 4 2 4 8 8 8 3 Tetratricopeptide repeat TPR_1 PF00515.28 KKK26015.1 - 0.011 15.5 20.4 0.75 9.7 0.8 5.8 5 2 2 7 7 7 0 Tetratricopeptide repeat TPR_14 PF13428.6 KKK26015.1 - 0.016 15.9 15.1 14 6.8 0.7 5.9 2 1 4 6 6 6 0 Tetratricopeptide repeat NSF PF02071.20 KKK26015.1 - 0.33 11.9 20.5 1.3 10.1 0.8 7.0 8 0 0 8 8 7 0 Aromatic-di-Alanine (AdAR) repeat FRB_dom PF08771.11 KKK26015.1 - 0.76 10.2 4.7 0.28 11.6 0.5 2.4 3 1 0 3 3 3 0 FKBP12-rapamycin binding domain MIT PF04212.18 KKK26015.1 - 7.7 6.7 16.6 4 7.6 1.1 4.5 1 1 3 4 4 4 0 MIT (microtubule interacting and transport) domain FMO-like PF00743.19 KKK26016.1 - 6.3e-13 48.0 0.1 5e-11 41.7 0.2 2.8 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KKK26016.1 - 3.4e-11 42.9 0.0 6.1e-08 32.3 0.0 2.4 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KKK26016.1 - 1.3e-10 41.3 0.0 3.4e-10 40.0 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KKK26016.1 - 5.4e-09 36.2 0.0 8.4e-05 22.6 0.0 2.8 3 0 0 3 3 3 2 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 KKK26016.1 - 1e-08 34.8 0.0 5.1e-05 22.7 0.0 3.4 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KKK26016.1 - 8.9e-08 31.6 0.0 0.0013 18.0 0.0 3.1 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 KKK26016.1 - 1.5e-06 28.1 0.0 0.00023 20.9 0.0 3.0 3 0 0 3 3 3 1 FAD dependent oxidoreductase Thi4 PF01946.17 KKK26016.1 - 0.0013 18.0 0.0 0.0031 16.8 0.0 1.6 2 0 0 2 2 2 1 Thi4 family Amino_oxidase PF01593.24 KKK26016.1 - 0.0014 18.0 0.0 0.084 12.2 0.0 2.1 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 KKK26016.1 - 0.0016 19.0 0.0 0.075 13.6 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 KKK26016.1 - 0.0087 16.1 0.0 3 7.9 0.0 2.5 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase GIDA PF01134.22 KKK26016.1 - 0.025 13.7 0.0 3.2 6.7 0.0 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_binding_2 PF00890.24 KKK26016.1 - 0.11 11.6 0.0 0.2 10.7 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain DUF1365 PF07103.11 KKK26017.1 - 1.8e-27 96.6 0.0 2.7e-27 96.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1365) HTH_Tnp_Tc5 PF03221.16 KKK26018.1 - 4.7e-18 65.0 0.0 8.7e-18 64.1 0.0 1.4 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.13 KKK26018.1 - 1.4e-05 24.6 0.1 2.7e-05 23.7 0.1 1.4 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_38 PF13936.6 KKK26018.1 - 0.00094 18.9 0.1 0.0022 17.7 0.1 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Tnp_4 PF13613.6 KKK26018.1 - 0.036 13.8 0.0 0.063 13.0 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease MarR PF01047.22 KKK26018.1 - 0.038 13.9 0.0 0.1 12.5 0.0 1.8 1 0 0 1 1 1 0 MarR family HTH_10 PF04967.12 KKK26018.1 - 0.13 12.1 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 HTH DNA binding domain HTH_23 PF13384.6 KKK26018.1 - 0.13 12.1 1.4 1.1 9.2 0.0 2.6 3 0 0 3 3 3 0 Homeodomain-like domain HTH_Crp_2 PF13545.6 KKK26018.1 - 0.16 12.0 0.0 0.32 11.0 0.0 1.4 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain Sigma70_r4 PF04545.16 KKK26018.1 - 0.18 11.4 0.1 0.36 10.4 0.1 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 CLU PF13236.6 KKK26020.1 - 8.3e-76 254.7 0.0 1.5e-75 253.8 0.0 1.4 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.7 KKK26020.1 - 3e-54 183.7 0.1 1.1e-53 181.8 0.0 2.0 2 0 0 2 2 2 1 Translation initiation factor eIF3 subunit 135 CLU_N PF15044.6 KKK26020.1 - 5.3e-25 87.6 0.0 1.6e-24 86.0 0.0 1.9 1 0 0 1 1 1 1 Mitochondrial function, CLU-N-term TPR_12 PF13424.6 KKK26020.1 - 9.9e-06 25.8 1.2 2.7e-05 24.4 1.2 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_10 PF13374.6 KKK26020.1 - 0.00019 21.2 0.9 0.0015 18.3 0.1 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat DUF727 PF05303.12 KKK26020.1 - 0.0092 16.0 0.1 0.025 14.6 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF727) TPR_8 PF13181.6 KKK26020.1 - 0.021 15.0 0.5 0.07 13.4 0.5 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.17 KKK26020.1 - 0.078 13.1 0.1 0.3 11.3 0.1 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat BRF1 PF07741.13 KKK26020.1 - 7.9 6.9 10.1 8.7 6.8 5.0 2.6 2 0 0 2 2 2 0 Brf1-like TBP-binding domain Ldh_1_N PF00056.23 KKK26025.1 - 6e-46 156.0 0.3 9.4e-46 155.4 0.0 1.4 2 0 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 KKK26025.1 - 2.2e-43 148.1 0.0 3.1e-43 147.6 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.19 KKK26025.1 - 0.00026 20.1 0.0 0.00039 19.5 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KKK26025.1 - 0.0057 16.6 0.0 0.012 15.5 0.0 1.6 1 0 0 1 1 1 1 NAD(P)H-binding Glyco_hydro_4 PF02056.16 KKK26025.1 - 0.0061 16.1 0.0 0.11 12.0 0.0 2.3 1 1 1 2 2 2 1 Family 4 glycosyl hydrolase Semialdhyde_dh PF01118.24 KKK26025.1 - 0.037 14.5 0.0 0.075 13.5 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Phosphodiest PF01663.22 KKK26027.1 - 7e-13 48.9 2.6 7.7e-09 35.6 0.4 2.2 1 1 1 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 KKK26027.1 - 8.9e-05 22.0 0.0 0.00031 20.2 0.0 1.8 2 0 0 2 2 2 1 Sulfatase Metalloenzyme PF01676.18 KKK26027.1 - 0.005 16.2 0.1 0.0084 15.5 0.1 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily DUF2207 PF09972.9 KKK26027.1 - 0.1 11.4 0.9 0.2 10.4 0.0 1.9 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) DUF229 PF02995.17 KKK26027.1 - 0.15 10.6 0.0 0.23 10.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF229) DUF2423 PF10338.9 KKK26028.1 - 4e-21 75.0 2.0 4e-21 75.0 2.0 2.1 3 0 0 3 3 3 1 Protein of unknown function (DUF2423) GAGE PF05831.11 KKK26028.1 - 0.19 12.3 5.0 0.072 13.6 2.8 1.6 1 1 1 2 2 2 0 GAGE protein PINIT PF14324.6 KKK26029.1 - 1.2e-40 139.2 0.1 2.6e-40 138.1 0.1 1.6 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.20 KKK26029.1 - 2.9e-22 78.2 6.7 5.4e-22 77.3 6.7 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger SAP PF02037.27 KKK26029.1 - 1.5e-07 31.0 2.9 2.2e-07 30.4 0.2 2.5 2 0 0 2 2 2 1 SAP domain zf-Nse PF11789.8 KKK26029.1 - 4.3e-07 29.7 2.1 1e-06 28.5 2.1 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-Sec23_Sec24 PF04810.15 KKK26029.1 - 0.15 12.1 0.8 0.38 10.9 0.6 1.8 1 1 0 1 1 1 0 Sec23/Sec24 zinc finger Prok-RING_4 PF14447.6 KKK26029.1 - 0.33 10.9 3.0 0.72 9.8 3.0 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 TRAPP PF04051.16 KKK26030.1 - 5.3e-48 162.5 0.0 6.2e-48 162.2 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component CBFD_NFYB_HMF PF00808.23 KKK26031.1 - 9.4e-19 67.5 0.5 1.6e-18 66.8 0.5 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KKK26031.1 - 8.6e-16 58.5 0.1 1.4e-15 57.8 0.1 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.10 KKK26031.1 - 0.067 13.5 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 CENP-S associating Centromere protein X Sec15 PF04091.12 KKK26032.1 - 4.5e-107 358.1 0.4 4.5e-107 358.1 0.4 2.0 2 0 0 2 2 2 1 Exocyst complex subunit Sec15-like COG2 PF06148.11 KKK26032.1 - 0.0012 18.9 6.5 0.0012 18.9 6.5 2.9 3 1 0 3 3 3 1 COG (conserved oligomeric Golgi) complex component, COG2 Sec8_exocyst PF04048.14 KKK26032.1 - 0.0013 18.6 4.8 0.0013 18.6 4.8 2.3 2 0 0 2 2 2 1 Sec8 exocyst complex component specific domain Sec5 PF15469.6 KKK26032.1 - 0.0051 16.6 6.6 0.017 14.9 2.8 2.8 2 0 0 2 2 2 1 Exocyst complex component Sec5 COG5 PF10392.9 KKK26032.1 - 0.0077 16.4 7.1 0.016 15.4 5.1 2.5 2 0 0 2 2 2 1 Golgi transport complex subunit 5 Vps51 PF08700.11 KKK26032.1 - 0.077 13.1 3.7 0.14 12.3 1.1 2.7 2 0 0 2 2 2 0 Vps51/Vps67 Vps54_N PF10475.9 KKK26032.1 - 0.089 12.1 11.2 0.059 12.7 7.9 2.0 2 0 0 2 2 2 0 Vacuolar-sorting protein 54, of GARP complex FUSC PF04632.12 KKK26032.1 - 2.7 6.4 6.6 4 5.8 6.6 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF3510 PF12022.8 KKK26032.1 - 4.2 7.8 8.3 4.6 7.6 0.0 3.9 3 2 1 5 5 5 0 Domain of unknown function (DUF3510) RRM_2 PF04059.12 KKK26033.1 - 2.8e-40 136.4 1.0 5.8e-40 135.4 0.6 1.8 2 0 0 2 2 2 1 RNA recognition motif 2 RRM_1 PF00076.22 KKK26033.1 - 1.1e-10 41.2 0.0 0.019 14.8 0.0 3.8 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CcdB PF01845.17 KKK26034.1 - 0.12 12.6 0.0 9.7 6.5 0.0 2.3 1 1 1 2 2 2 0 CcdB protein Fcf2 PF08698.11 KKK26035.1 - 1.3e-36 124.9 1.2 2.3e-36 124.1 0.1 2.0 2 1 1 3 3 3 1 Fcf2 pre-rRNA processing PNP_UDP_1 PF01048.20 KKK26036.1 - 1.7e-44 151.8 0.1 2.3e-44 151.4 0.1 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily Ribosomal_S10 PF00338.22 KKK26037.1 - 1.6e-28 98.8 0.0 3.7e-28 97.6 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein S10p/S20e Mito_carr PF00153.27 KKK26038.1 - 7.5e-68 224.5 0.8 1.4e-23 82.7 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein RRM_1 PF00076.22 KKK26039.1 - 1.2e-35 121.1 0.0 8.6e-17 60.7 0.1 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KKK26039.1 - 1.2e-05 24.9 0.1 0.077 12.6 0.0 2.3 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KKK26039.1 - 0.00016 21.7 0.0 0.001 19.2 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif OB_RNB PF08206.11 KKK26039.1 - 0.0034 17.0 0.2 0.33 10.7 0.1 2.4 2 0 0 2 2 2 1 Ribonuclease B OB domain Cas_Cas2CT1978 PF09707.10 KKK26039.1 - 0.03 14.4 0.0 4.7 7.4 0.0 2.3 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Cas2CT1978) RRM_occluded PF16842.5 KKK26039.1 - 0.035 14.0 0.0 0.073 12.9 0.0 1.5 1 0 0 1 1 1 0 Occluded RNA-recognition motif Limkain-b1 PF11608.8 KKK26039.1 - 0.12 12.4 0.2 2.5 8.2 0.1 2.2 2 0 0 2 2 2 0 Limkain b1 CMV_1a_C PF12503.8 KKK26039.1 - 0.15 12.1 0.5 13 5.9 0.1 2.7 2 1 1 3 3 3 0 Cucumber mosaic virus 1a protein C terminal Tom7 PF08038.12 KKK26040.1 - 1.1e-22 79.3 0.3 1.3e-22 79.2 0.3 1.1 1 0 0 1 1 1 1 TOM7 family Ribosomal_L28e PF01778.17 KKK26041.1 - 1.1e-35 122.9 0.3 1.6e-35 122.3 0.3 1.3 1 0 0 1 1 1 1 Ribosomal L28e protein family Med3 PF11593.8 KKK26041.1 - 1.2 8.2 8.2 1.5 7.9 8.2 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF2015 PF09435.10 KKK26042.1 - 1.1e-46 157.2 0.0 1.3e-46 157.0 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2015) Lactonase PF10282.9 KKK26043.1 - 5e-76 256.2 0.0 1.3e-75 254.8 0.0 1.5 1 1 0 1 1 1 1 Lactonase, 7-bladed beta-propeller He_PIG PF05345.12 KKK26043.1 - 0.0019 18.4 1.9 0.31 11.3 0.7 2.8 2 0 0 2 2 2 2 Putative Ig domain Glyco_hydro_72 PF03198.14 KKK26049.1 - 1.3e-129 432.0 4.9 1.9e-129 431.5 4.9 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.13 KKK26049.1 - 1.8e-22 79.8 5.1 5.4e-22 78.3 5.1 1.9 1 0 0 1 1 1 1 X8 domain Glyco_hydro_2_C PF02836.17 KKK26049.1 - 0.029 13.5 0.3 0.066 12.3 0.3 1.7 1 1 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain Cellulase PF00150.18 KKK26049.1 - 0.048 13.1 0.3 0.11 11.9 0.2 1.6 1 1 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) GCV_T PF01571.21 KKK26062.1 - 1.6e-79 266.9 0.0 2.4e-79 266.3 0.0 1.3 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 KKK26062.1 - 5.9e-15 55.0 0.2 1.3e-14 53.8 0.2 1.6 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain Aa_trans PF01490.18 KKK26063.1 - 3.1e-29 101.9 33.8 3.9e-29 101.6 33.8 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein CBF PF03914.17 KKK26064.1 - 1.7e-54 184.4 5.3 3.9e-54 183.2 0.0 3.1 2 0 0 2 2 2 1 CBF/Mak21 family Cnd1 PF12717.7 KKK26064.1 - 0.093 12.8 0.1 1.3 9.0 0.0 2.6 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 DUF2477 PF10631.9 KKK26064.1 - 1 10.0 5.3 0.32 11.7 1.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2477) V-ATPase_H_N PF03224.14 KKK26065.1 - 7.2e-84 281.8 0.0 1e-83 281.3 0.0 1.2 1 0 0 1 1 1 1 V-ATPase subunit H V-ATPase_H_C PF11698.8 KKK26065.1 - 1.4e-37 128.4 0.0 8.2e-37 125.9 0.0 2.3 2 0 0 2 2 2 1 V-ATPase subunit H WD40 PF00400.32 KKK26066.1 - 2.7e-44 148.2 11.7 3.3e-09 37.2 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKK26066.1 - 1.9e-05 24.9 0.2 7.7 6.9 0.0 4.6 2 2 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KKK26066.1 - 0.064 11.9 2.7 11 4.6 0.0 4.2 2 1 2 5 5 5 0 Nucleoporin Nup120/160 WD40_like PF17005.5 KKK26066.1 - 0.12 11.6 0.0 0.25 10.6 0.0 1.5 2 0 0 2 2 2 0 WD40-like domain AAA PF00004.29 KKK26067.1 - 4.7e-15 56.2 0.0 9e-15 55.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_10 PF17872.1 KKK26067.1 - 1.4e-12 47.6 0.5 8.5e-12 45.1 0.6 2.3 2 1 0 2 2 2 1 AAA lid domain AAA_22 PF13401.6 KKK26067.1 - 4.4e-10 40.0 0.0 1.4e-09 38.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KKK26067.1 - 1.9e-09 38.2 1.0 7.4e-09 36.2 0.0 2.5 2 2 0 2 2 2 1 AAA ATPase domain BAH PF01426.18 KKK26067.1 - 2.4e-05 24.2 0.0 6.2e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 BAH domain AAA_19 PF13245.6 KKK26067.1 - 0.002 18.5 0.1 0.006 16.9 0.1 1.8 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 KKK26067.1 - 0.0023 18.2 0.0 0.007 16.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KKK26067.1 - 0.0054 16.9 0.0 0.1 12.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KKK26067.1 - 0.014 15.3 0.0 0.05 13.5 0.0 1.9 1 1 0 1 1 1 0 NACHT domain AAA_11 PF13086.6 KKK26067.1 - 0.015 15.1 0.5 0.035 13.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KKK26067.1 - 0.046 14.3 0.0 0.11 13.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_32 PF13654.6 KKK26067.1 - 0.049 12.4 0.0 0.087 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 KKK26067.1 - 0.05 12.8 0.0 0.11 11.7 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) PIF1 PF05970.14 KKK26067.1 - 0.081 12.1 0.0 0.19 10.9 0.0 1.5 1 0 0 1 1 1 0 PIF1-like helicase ATPase_2 PF01637.18 KKK26067.1 - 0.12 12.3 0.0 2.8 7.8 0.0 2.3 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea ssDBP PF17878.1 KKK26067.1 - 0.12 12.6 0.0 0.29 11.4 0.0 1.6 1 0 0 1 1 1 0 Single-stranded DNA-binding protein Kinesin PF00225.23 KKK26067.1 - 0.17 10.7 0.0 0.32 9.9 0.0 1.4 1 0 0 1 1 1 0 Kinesin motor domain AAA_30 PF13604.6 KKK26067.1 - 0.54 9.9 3.2 0.21 11.3 0.3 1.8 2 0 0 2 2 2 0 AAA domain TMF_TATA_bd PF12325.8 KKK26068.1 - 4.7e-40 136.4 11.4 4.7e-40 136.4 11.4 6.4 2 1 4 7 7 7 1 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.8 KKK26068.1 - 9.9e-18 63.9 12.5 9.9e-18 63.9 12.5 8.4 6 3 3 9 9 9 2 TATA element modulatory factor 1 DNA binding ATG16 PF08614.11 KKK26068.1 - 2.2e-05 24.8 6.1 2.2e-05 24.8 6.1 5.4 3 1 2 5 5 5 2 Autophagy protein 16 (ATG16) Rab5-bind PF09311.11 KKK26068.1 - 0.0026 17.2 36.6 0.0026 17.2 36.6 3.6 2 1 2 4 4 4 2 Rabaptin-like protein SlyX PF04102.12 KKK26068.1 - 0.016 15.8 2.2 0.016 15.8 2.2 9.3 4 2 6 10 10 10 0 SlyX DUF2443 PF10398.9 KKK26068.1 - 4.9 7.3 6.4 5.9 7.0 0.1 4.2 4 0 0 4 4 4 0 Protein of unknown function (DUF2443) NPV_P10 PF05531.12 KKK26068.1 - 6.1 7.4 24.7 0.53 10.8 4.9 5.7 5 2 0 5 5 5 0 Nucleopolyhedrovirus P10 protein Filament PF00038.21 KKK26068.1 - 8.3 5.9 77.9 0.25 10.9 6.8 3.6 2 1 1 3 3 3 0 Intermediate filament protein Ank_2 PF12796.7 KKK26069.1 - 1.6e-41 140.7 4.5 7.6e-14 52.1 0.6 3.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KKK26069.1 - 3.3e-30 103.7 1.0 1.2e-07 31.8 0.0 4.7 2 2 4 6 6 6 6 Ankyrin repeats (many copies) Ank_4 PF13637.6 KKK26069.1 - 3.1e-28 97.8 0.6 5.2e-07 30.1 0.0 5.8 1 1 5 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KKK26069.1 - 1.6e-26 89.4 1.3 2.1e-05 24.5 0.0 6.2 6 0 0 6 6 6 6 Ankyrin repeat Ank PF00023.30 KKK26069.1 - 2.8e-23 81.3 4.3 2e-05 24.8 0.0 6.1 6 0 0 6 6 6 5 Ankyrin repeat Dabb PF07876.12 KKK26070.1 - 2.1e-23 82.8 0.0 2.3e-23 82.6 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain DUF4390 PF14334.6 KKK26070.1 - 0.21 11.0 0.0 0.28 10.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4390) tRNA-synt_2b PF00587.25 KKK26071.1 - 5.7e-30 104.6 0.0 1.2e-29 103.6 0.0 1.5 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) NUDIX PF00293.28 KKK26071.1 - 5.3e-25 88.0 0.9 1.1e-24 86.9 0.9 1.5 1 0 0 1 1 1 1 NUDIX domain HGTP_anticodon PF03129.20 KKK26071.1 - 1.6e-09 37.8 0.1 4.7e-09 36.3 0.1 1.8 2 0 0 2 2 2 1 Anticodon binding domain KH_1 PF00013.29 KKK26072.1 - 0.0097 15.7 0.0 0.59 10.0 0.0 2.4 2 0 0 2 2 2 2 KH domain Prefoldin PF02996.17 KKK26073.1 - 6.7e-13 48.6 1.1 4.6e-12 45.9 1.1 2.0 1 1 0 1 1 1 1 Prefoldin subunit DASH_Hsk3 PF08227.11 KKK26073.1 - 0.013 15.8 1.9 0.12 12.8 0.1 2.3 2 0 0 2 2 2 0 DASH complex subunit Hsk3 like CLZ PF16526.5 KKK26073.1 - 0.029 14.7 2.0 0.93 9.9 0.1 2.3 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Med28 PF11594.8 KKK26073.1 - 0.059 13.5 0.1 0.13 12.3 0.0 1.5 2 0 0 2 2 2 0 Mediator complex subunit 28 DUF883 PF05957.13 KKK26073.1 - 0.19 12.4 1.8 7.8 7.2 0.6 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) FAD_binding_1 PF00667.20 KKK26081.1 - 2.9e-44 151.3 0.0 4.1e-44 150.8 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 KKK26081.1 - 4.4e-10 40.2 0.0 1.4e-09 38.6 0.0 1.9 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain EF-hand_1 PF00036.32 KKK26083.1 - 6.6e-23 78.5 10.8 1.9e-07 30.1 0.1 4.7 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 KKK26083.1 - 1.1e-22 80.3 9.1 1.6e-15 57.3 1.0 3.7 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_6 PF13405.6 KKK26083.1 - 2.8e-22 76.7 5.2 2e-05 24.2 0.1 5.1 4 1 1 5 5 5 4 EF-hand domain EF-hand_5 PF13202.6 KKK26083.1 - 1.5e-15 55.9 8.9 0.0007 19.0 0.4 4.6 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 KKK26083.1 - 1.5e-13 50.4 10.8 2.2e-05 24.2 0.6 3.9 2 2 1 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.7 KKK26083.1 - 3.9e-07 30.0 5.2 0.02 14.9 0.2 3.9 1 1 3 4 4 4 3 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 KKK26083.1 - 0.00096 19.4 0.5 0.17 12.3 0.1 3.7 3 1 1 4 4 4 1 EF-hand domain EF-hand_10 PF14788.6 KKK26083.1 - 0.053 13.4 0.4 1.4 8.8 0.1 2.9 3 0 0 3 3 3 0 EF hand Zn_clus PF00172.18 KKK26083.1 - 0.053 13.7 3.3 0.12 12.6 3.3 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Abhydrolase_3 PF07859.13 KKK26084.1 - 6.1e-24 85.1 0.1 1.1e-23 84.2 0.1 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KKK26084.1 - 1.3e-14 53.8 0.0 5.5e-14 51.8 0.0 1.7 1 1 0 1 1 1 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 KKK26084.1 - 0.0023 17.5 0.0 0.0044 16.5 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 KKK26084.1 - 0.0024 18.5 0.4 0.0034 18.0 0.4 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.28 KKK26084.1 - 0.03 13.2 0.0 0.047 12.6 0.0 1.2 1 0 0 1 1 1 0 Carboxylesterase family TRI12 PF06609.13 KKK26085.1 - 3.3e-29 101.8 26.0 4.2e-29 101.4 26.0 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 KKK26085.1 - 3.1e-21 75.7 48.9 1.3e-20 73.6 45.8 2.5 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KKK26085.1 - 1.4e-07 30.7 10.3 1.4e-07 30.7 10.3 3.7 3 1 1 4 4 4 1 Sugar (and other) transporter Methyltransf_23 PF13489.6 KKK26086.1 - 8e-16 58.3 0.0 1.3e-15 57.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KKK26086.1 - 1.6e-12 47.9 0.0 9e-12 45.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KKK26086.1 - 1.2e-09 38.8 0.0 3.6e-09 37.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKK26086.1 - 3.8e-09 37.1 0.0 6e-08 33.3 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KKK26086.1 - 5.3e-09 36.1 0.0 1.3e-08 34.8 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 KKK26086.1 - 0.074 14.1 0.0 0.16 13.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain RPN2_C PF18004.1 KKK26087.1 - 8.5e-57 191.5 8.9 8.5e-57 191.5 8.9 2.4 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN2 C-terminal domain PC_rep PF01851.22 KKK26087.1 - 4.3e-36 121.5 22.6 7.2e-10 38.8 0.1 8.5 8 0 0 8 8 8 6 Proteasome/cyclosome repeat HEAT_2 PF13646.6 KKK26087.1 - 7.7e-21 74.3 0.2 1.9e-14 53.8 0.0 3.3 2 1 2 4 4 4 3 HEAT repeats HEAT_EZ PF13513.6 KKK26087.1 - 4.4e-08 33.5 0.2 5.7e-05 23.5 0.1 4.5 3 1 1 4 4 4 2 HEAT-like repeat HEAT PF02985.22 KKK26087.1 - 5.6e-05 23.0 0.1 5 7.7 0.0 4.6 4 0 0 4 4 4 1 HEAT repeat Cnd1 PF12717.7 KKK26087.1 - 0.0031 17.6 0.4 0.24 11.4 0.0 3.0 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_PBS PF03130.16 KKK26087.1 - 0.039 14.6 1.8 0.96 10.3 0.0 3.7 3 0 0 3 3 3 0 PBS lyase HEAT-like repeat CtsR_C PF17727.1 KKK26087.1 - 0.042 14.0 0.2 0.22 11.7 0.2 2.3 1 0 0 1 1 1 0 CtsR C-terminal dimerization domain GPI-anchored PF10342.9 KKK26090.1 - 1.7e-14 54.4 0.0 3.6e-14 53.3 0.0 1.6 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family KRE9 PF05390.11 KKK26090.1 - 8.5e-10 39.3 4.2 1.8e-09 38.3 4.2 1.5 1 0 0 1 1 1 1 Yeast cell wall synthesis protein KRE9/KNH1 TIP41 PF04176.13 KKK26091.1 - 3.5e-72 241.5 0.2 4.6e-72 241.1 0.2 1.1 1 0 0 1 1 1 1 TIP41-like family Na_Ca_ex PF01699.24 KKK26092.1 - 4e-22 78.8 31.1 1.9e-13 50.6 8.4 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein HAUS-augmin3 PF14932.6 KKK26092.1 - 0.0029 17.2 6.6 0.0029 17.2 6.6 3.0 3 1 0 3 3 3 1 HAUS augmin-like complex subunit 3 DUF898 PF05987.13 KKK26092.1 - 0.027 13.5 0.1 0.074 12.1 0.1 1.7 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF898) SlyX PF04102.12 KKK26092.1 - 0.038 14.6 15.7 0.11 13.2 3.8 3.8 3 1 1 4 4 4 0 SlyX MIG-14_Wnt-bd PF06664.12 KKK26092.1 - 1.7 7.8 8.2 0.096 11.9 1.3 2.1 2 0 0 2 2 2 0 Wnt-binding factor required for Wnt secretion SRPRB PF09439.10 KKK26093.1 - 7.8e-26 90.6 0.1 4.8e-24 84.8 0.1 2.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.21 KKK26093.1 - 6.1e-08 32.3 0.0 0.004 16.6 0.0 2.6 2 1 0 2 2 2 2 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KKK26093.1 - 1.7e-05 24.9 0.0 3.1e-05 24.0 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KKK26093.1 - 7.6e-05 23.2 0.1 0.00018 21.9 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.27 KKK26093.1 - 0.00012 22.6 0.0 0.0002 21.9 0.0 1.4 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 KKK26093.1 - 0.00098 19.1 0.2 0.0086 16.0 0.2 2.2 2 0 0 2 2 2 1 RsgA GTPase Sigma54_activat PF00158.26 KKK26093.1 - 0.0018 18.0 0.0 1.5 8.5 0.0 2.2 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_29 PF13555.6 KKK26093.1 - 0.0029 17.3 0.1 0.0063 16.2 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain GTP_EFTU PF00009.27 KKK26093.1 - 0.0041 16.7 0.0 0.11 12.1 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 KKK26093.1 - 0.01 16.1 0.1 0.02 15.2 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_21 PF13304.6 KKK26093.1 - 0.015 15.2 0.0 0.024 14.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system PduV-EutP PF10662.9 KKK26093.1 - 0.03 14.1 0.1 0.056 13.2 0.1 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_5 PF07728.14 KKK26093.1 - 0.07 13.1 0.0 0.16 11.9 0.0 1.7 2 0 0 2 2 1 0 AAA domain (dynein-related subfamily) AAA_23 PF13476.6 KKK26093.1 - 0.073 13.6 0.0 0.15 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain Roc PF08477.13 KKK26093.1 - 0.074 13.3 0.0 0.32 11.2 0.0 2.0 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Rad17 PF03215.15 KKK26093.1 - 0.11 12.4 0.1 0.19 11.6 0.1 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_18 PF13238.6 KKK26093.1 - 0.14 12.7 0.0 0.28 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 KKK26093.1 - 0.15 11.4 0.0 0.33 10.3 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 KKK26093.1 - 0.17 11.4 0.1 0.29 10.6 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 KKK26093.1 - 0.17 11.6 0.0 0.32 10.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain Septin PF00735.18 KKK26093.1 - 0.2 10.9 0.0 0.35 10.1 0.0 1.3 1 0 0 1 1 1 0 Septin AAA_28 PF13521.6 KKK26093.1 - 0.2 11.9 0.1 0.32 11.2 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KKK26093.1 - 0.22 11.7 0.4 0.34 11.0 0.3 1.5 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 KKK26093.1 - 0.28 11.6 1.0 1 9.8 1.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AA_kinase PF00696.28 KKK26094.1 - 9.9e-40 136.6 0.7 1.4e-39 136.1 0.7 1.2 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.20 KKK26094.1 - 5.4e-18 64.7 0.2 2.3e-16 59.5 0.0 2.4 2 0 0 2 2 2 1 PUA domain PALP PF00291.25 KKK26095.1 - 7.8e-67 225.7 0.1 9.5e-67 225.5 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.28 KKK26095.1 - 2.9e-13 50.0 0.1 1.3e-07 31.9 0.0 2.8 2 0 0 2 2 2 2 CBS domain DAP_epimerase PF01678.19 KKK26095.1 - 0.076 13.2 0.0 0.45 10.7 0.0 2.1 2 0 0 2 2 2 0 Diaminopimelate epimerase ACP_syn_III_C PF08541.10 KKK26095.1 - 0.68 10.1 3.0 14 5.9 0.0 2.9 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Pkinase PF00069.25 KKK26096.1 - 1.9e-71 240.5 0.0 2.4e-71 240.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK26096.1 - 1.8e-44 152.0 0.0 2.3e-44 151.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KKK26096.1 - 1e-07 31.5 0.0 3.8e-07 29.7 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 KKK26096.1 - 7.7e-05 22.1 0.2 0.00013 21.4 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KKK26096.1 - 0.0041 16.1 0.0 0.0073 15.3 0.0 1.4 1 0 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 KKK26096.1 - 0.061 12.9 0.1 0.21 11.2 0.0 1.8 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 KKK26096.1 - 0.066 13.1 0.1 0.097 12.6 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 KKK26096.1 - 0.093 12.3 0.1 0.26 10.8 0.0 1.7 2 1 1 3 3 3 0 RIO1 family NumbF PF06311.12 KKK26097.1 - 0.021 15.4 1.3 0.034 14.7 1.3 1.5 1 0 0 1 1 1 0 NUMB domain Peptidase_M76 PF09768.9 KKK26098.1 - 8.1e-75 250.3 2.5 9.8e-75 250.0 2.5 1.1 1 0 0 1 1 1 1 Peptidase M76 family HNH_5 PF14279.6 KKK26098.1 - 0.016 15.1 0.8 0.11 12.4 0.1 2.3 2 0 0 2 2 2 0 HNH endonuclease SprT-like PF10263.9 KKK26098.1 - 0.03 14.2 2.1 0.035 14.0 0.8 1.7 1 1 1 2 2 2 0 SprT-like family Peptidase_M13 PF01431.21 KKK26098.1 - 0.036 13.7 0.1 0.055 13.1 0.1 1.3 1 0 0 1 1 1 0 Peptidase family M13 Peptidase_M91 PF14891.6 KKK26098.1 - 0.088 13.1 0.1 0.14 12.5 0.1 1.3 1 0 0 1 1 1 0 Effector protein Ank_2 PF12796.7 KKK26099.1 - 3.5e-39 133.2 0.7 8.5e-13 48.7 0.1 3.5 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) DHHC PF01529.20 KKK26099.1 - 2.5e-31 108.6 11.5 2.5e-31 108.6 11.5 2.7 2 1 0 2 2 2 1 DHHC palmitoyltransferase Ank_5 PF13857.6 KKK26099.1 - 1.7e-27 95.1 3.2 4.6e-09 36.4 0.0 4.7 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KKK26099.1 - 4.2e-23 78.9 4.4 5.8e-08 32.4 0.1 5.9 5 0 0 5 5 5 4 Ankyrin repeat Ank PF00023.30 KKK26099.1 - 6.9e-23 80.0 1.7 2.3e-06 27.8 0.0 5.3 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.6 KKK26099.1 - 2.6e-22 78.9 12.3 4.5e-07 30.3 0.4 4.8 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Cyclin PF08613.11 KKK26101.1 - 2.9e-36 125.3 0.0 3.4e-36 125.0 0.0 1.1 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 KKK26101.1 - 0.0051 16.6 0.1 0.0085 15.8 0.1 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain MFS_1 PF07690.16 KKK26102.1 - 1.6e-44 152.3 50.8 1.6e-44 152.3 50.8 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KKK26102.1 - 5.1e-15 54.9 15.8 5.1e-15 54.9 15.8 2.3 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KKK26102.1 - 2.2e-12 46.6 15.4 2.2e-12 46.6 15.4 3.3 3 2 1 4 4 4 1 Sugar (and other) transporter Abhydrolase_8 PF06259.12 KKK26102.1 - 0.091 12.4 3.1 1.5 8.4 0.8 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase Phage_holin_5_1 PF06946.11 KKK26102.1 - 1.4 9.3 6.5 13 6.2 1.0 4.3 3 1 1 4 4 4 0 Bacteriophage A118-like holin, Hol118 Peptidase_M49 PF03571.15 KKK26103.1 - 1.1e-58 199.0 0.0 1.4e-58 198.6 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M49 COX6A PF02046.15 KKK26105.1 - 1.5e-44 151.0 0.1 2e-44 150.6 0.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa Exo_endo_phos PF03372.23 KKK26106.1 - 1.8e-13 50.5 0.2 3e-13 49.8 0.2 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 KKK26106.1 - 0.0027 17.5 0.0 2.8 7.8 0.0 2.5 2 0 0 2 2 2 2 Endonuclease-reverse transcriptase zf-GRF PF06839.12 KKK26106.1 - 0.0077 16.3 1.2 0.019 15.1 1.2 1.7 1 0 0 1 1 1 1 GRF zinc finger Peptidase_M49 PF03571.15 KKK26107.1 - 4.8e-96 322.3 0.0 5.3e-96 322.2 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M49 ANAPC5 PF12862.7 KKK26108.1 - 1.7e-36 124.1 5.1 4.5e-36 122.8 2.2 2.5 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 5 TPR_12 PF13424.6 KKK26108.1 - 0.018 15.3 7.8 4.3 7.7 0.1 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF627 PF04781.12 KKK26108.1 - 0.049 13.7 0.1 0.36 10.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF627) TPR_10 PF13374.6 KKK26108.1 - 0.052 13.4 0.8 0.24 11.3 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 KKK26108.1 - 0.054 13.6 1.0 30 5.1 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF953 PF06110.11 KKK26109.1 - 5.5e-14 51.8 0.0 6.3e-14 51.6 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Thioredoxin_9 PF14595.6 KKK26109.1 - 0.00015 21.5 0.0 0.0002 21.2 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin HyaE PF07449.11 KKK26109.1 - 0.0027 17.6 0.0 0.0048 16.8 0.0 1.5 1 1 0 1 1 1 1 Hydrogenase-1 expression protein HyaE FAD_binding_4 PF01565.23 KKK26110.1 - 8.7e-21 74.1 0.8 2.3e-20 72.8 0.8 1.8 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KKK26110.1 - 3e-08 33.6 0.2 6.6e-08 32.5 0.2 1.6 1 0 0 1 1 1 1 Berberine and berberine like ParA PF10609.9 KKK26111.1 - 4.8e-96 321.0 0.0 5.5e-96 320.8 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 KKK26111.1 - 3.2e-06 27.2 0.0 1.2e-05 25.4 0.0 1.9 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.15 KKK26111.1 - 1.2e-05 24.6 2.1 0.00031 20.0 0.5 2.6 1 1 0 2 2 2 1 Anion-transporting ATPase AAA_31 PF13614.6 KKK26111.1 - 1.8e-05 24.7 0.0 9.3e-05 22.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_26 PF13500.6 KKK26111.1 - 0.013 15.3 0.0 0.68 9.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 KKK26111.1 - 0.015 15.2 0.0 0.031 14.2 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase MipZ PF09140.11 KKK26111.1 - 0.059 12.7 0.0 0.16 11.3 0.0 1.6 1 1 0 1 1 1 0 ATPase MipZ CLP1_P PF16575.5 KKK26111.1 - 0.068 13.0 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop TsaE PF02367.17 KKK26111.1 - 0.084 12.9 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 KKK26111.1 - 0.087 12.5 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KKK26111.1 - 0.14 11.8 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain Asp PF00026.23 KKK26113.1 - 5.3e-63 213.3 8.4 6.4e-63 213.1 8.4 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KKK26113.1 - 8.5e-10 39.2 2.8 0.00086 19.6 0.1 2.9 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KKK26113.1 - 0.001 19.6 2.0 0.9 10.2 0.4 3.0 2 1 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 KKK26113.1 - 0.0025 18.3 1.0 2.5 8.7 0.0 3.0 2 2 0 2 2 2 2 gag-polyprotein putative aspartyl protease TAXi_C PF14541.6 KKK26113.1 - 0.16 11.8 0.9 1.7 8.4 0.0 2.8 4 0 0 4 4 4 0 Xylanase inhibitor C-terminal zf-CSL PF05207.13 KKK26122.1 - 7.9e-20 70.3 1.5 1.3e-19 69.6 1.5 1.4 1 0 0 1 1 1 1 CSL zinc finger DnaJ PF00226.31 KKK26122.1 - 0.0025 17.9 0.0 0.0038 17.3 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain DUF1349 PF07081.11 KKK26123.1 - 1.9e-21 76.6 0.0 2.4e-21 76.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1349) Proteasome PF00227.26 KKK26125.1 - 7.4e-47 159.3 0.2 5.7e-32 110.7 0.0 2.3 2 0 0 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.9 KKK26125.1 - 2.5e-12 46.2 0.3 6.3e-12 44.9 0.0 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature KAR9 PF08580.10 KKK26126.1 - 0.018 13.6 6.5 0.022 13.3 6.5 1.0 1 0 0 1 1 1 0 Yeast cortical protein KAR9 WBS_methylT PF12589.8 KKK26127.1 - 1.7e-15 57.5 1.9 2.9e-15 56.8 1.9 1.3 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.12 KKK26127.1 - 5.9e-12 46.1 0.0 1e-11 45.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKK26127.1 - 1.6e-11 44.7 0.0 6.3e-11 42.8 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KKK26127.1 - 1.5e-05 25.7 0.0 4.1e-05 24.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KKK26127.1 - 3.8e-05 23.5 0.0 5.7e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KKK26127.1 - 0.0013 18.5 0.0 0.0022 17.8 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.6 KKK26127.1 - 0.0042 16.9 0.0 0.0062 16.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KKK26127.1 - 0.0047 16.3 0.1 0.052 12.9 0.0 2.2 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family CMAS PF02353.20 KKK26127.1 - 0.019 14.3 0.0 0.27 10.5 0.0 2.0 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase Methyltransf_33 PF10017.9 KKK26127.1 - 0.077 12.1 0.0 0.16 11.1 0.0 1.4 1 1 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent Erv26 PF04148.13 KKK26128.1 - 8.9e-94 313.1 0.1 1e-93 312.9 0.1 1.0 1 0 0 1 1 1 1 Transmembrane adaptor Erv26 Cys_Knot_tox PF17486.2 KKK26129.1 - 0.019 15.2 0.4 1.3 9.3 0.0 2.1 1 1 1 2 2 2 0 Cystine knot toxins Antimicrobial_5 PF08026.11 KKK26129.1 - 0.14 12.3 0.1 16 5.6 0.0 2.2 2 0 0 2 2 2 0 Bee antimicrobial peptide DUF1580 PF07618.11 KKK26129.1 - 0.15 11.7 0.1 7.4 6.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1580) Iso_dh PF00180.20 KKK26130.1 - 1.2e-83 281.2 0.0 1.5e-83 280.8 0.0 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase HSP70 PF00012.20 KKK26131.1 - 4.8e-10 38.3 0.3 3.5e-09 35.4 0.1 1.9 2 0 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 KKK26131.1 - 0.11 11.3 0.0 0.39 9.5 0.0 1.8 2 0 0 2 2 2 0 MreB/Mbl protein TFIIA PF03153.13 KKK26131.1 - 0.38 10.7 6.0 0.57 10.1 6.0 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Peptidase_C13 PF01650.18 KKK26132.1 - 8.8e-41 140.1 0.1 1.2e-40 139.6 0.1 1.1 1 0 0 1 1 1 1 Peptidase C13 family Mito_carr PF00153.27 KKK26134.1 - 5.4e-43 144.8 8.6 8e-16 57.7 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF3445 PF11927.8 KKK26135.1 - 9.6e-74 247.8 0.1 1.2e-73 247.5 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) INTS5_N PF14837.6 KKK26135.1 - 0.0097 15.5 0.0 0.018 14.7 0.0 1.3 1 0 0 1 1 1 1 Integrator complex subunit 5 N-terminus 4HBT_3 PF13622.6 KKK26136.1 - 1.1e-75 255.1 0.1 1.4e-75 254.8 0.1 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 KKK26136.1 - 6.2e-24 84.3 0.0 3.5e-12 46.3 0.0 4.1 3 1 0 3 3 3 3 Acyl-CoA thioesterase Succ_CoA_lig PF13607.6 KKK26136.1 - 0.063 13.1 0.0 0.28 11.0 0.0 2.0 2 0 0 2 2 2 0 Succinyl-CoA ligase like flavodoxin domain NB-ARC PF00931.22 KKK26146.1 - 9.3e-11 41.4 0.0 1.4e-10 40.8 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain PNP_UDP_1 PF01048.20 KKK26146.1 - 8.4e-09 35.0 0.5 6.6e-08 32.1 0.5 2.3 1 1 0 1 1 1 1 Phosphorylase superfamily NACHT PF05729.12 KKK26146.1 - 1.8e-05 24.7 0.0 3.9e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KKK26146.1 - 3.2e-05 24.4 0.0 8.6e-05 23.0 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KKK26146.1 - 0.019 15.2 0.0 0.11 12.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KKK26146.1 - 0.094 12.4 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain TrwB_AAD_bind PF10412.9 KKK26146.1 - 0.16 10.9 0.0 0.33 9.8 0.0 1.5 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain TPR_10 PF13374.6 KKK26147.1 - 1.8e-33 113.4 3.5 1.9e-12 46.6 0.0 3.4 3 1 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 KKK26147.1 - 4.2e-29 100.6 0.5 9e-13 48.3 0.1 3.1 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KKK26147.1 - 2.6e-07 30.2 0.7 0.04 14.0 0.1 3.0 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 KKK26147.1 - 6.7e-06 26.1 0.1 1.4 9.4 0.0 3.7 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 KKK26147.1 - 1.1e-05 25.1 0.1 0.02 14.9 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 KKK26147.1 - 1.4e-05 24.7 0.1 0.084 12.7 0.0 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_4 PF07721.14 KKK26147.1 - 5.3e-05 23.4 0.0 0.29 11.9 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 KKK26147.1 - 0.015 16.0 0.0 4.4 8.0 0.0 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat N1221 PF07923.13 KKK26147.1 - 0.072 12.3 0.0 0.099 11.8 0.0 1.3 1 0 0 1 1 1 0 N1221-like protein ANAPC3 PF12895.7 KKK26147.1 - 0.074 13.3 0.1 0.42 10.9 0.0 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 KKK26147.1 - 0.08 13.5 0.1 9.3 6.8 0.0 2.9 2 1 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 KKK26147.1 - 0.1 13.3 0.2 13 6.7 0.0 3.4 4 0 0 4 4 3 0 Tetratricopeptide repeat SNARE PF05739.19 KKK26148.1 - 3e-10 39.9 0.5 3e-10 39.9 0.5 2.0 2 0 0 2 2 1 1 SNARE domain Syntaxin PF00804.25 KKK26148.1 - 1.1e-07 31.7 11.5 1.1e-07 31.7 11.5 1.7 2 0 0 2 2 2 1 Syntaxin Use1 PF09753.9 KKK26148.1 - 9.4e-06 25.5 4.3 1.3e-05 25.0 4.3 1.2 1 0 0 1 1 1 1 Membrane fusion protein Use1 Prominin PF05478.11 KKK26148.1 - 0.0013 16.8 2.4 0.0013 16.8 2.4 1.4 1 1 0 1 1 1 1 Prominin LMBR1 PF04791.16 KKK26148.1 - 0.0051 15.8 1.6 0.0063 15.5 1.6 1.1 1 0 0 1 1 1 1 LMBR1-like membrane protein Syntaxin_2 PF14523.6 KKK26148.1 - 0.0069 16.7 10.6 0.02 15.2 3.2 2.8 2 2 0 2 2 2 1 Syntaxin-like protein MCPsignal PF00015.21 KKK26148.1 - 0.0084 15.9 6.1 0.023 14.5 3.5 2.3 1 1 0 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF2935 PF11155.8 KKK26148.1 - 0.011 16.1 0.1 0.51 10.7 0.6 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF2935) DUF2207 PF09972.9 KKK26148.1 - 0.013 14.3 0.7 0.37 9.5 0.0 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) HisKA_3 PF07730.13 KKK26148.1 - 0.017 15.7 12.0 0.26 11.8 0.1 4.0 3 2 1 4 4 4 0 Histidine kinase CD225 PF04505.12 KKK26148.1 - 0.024 14.7 0.6 0.061 13.5 0.6 1.7 1 0 0 1 1 1 0 Interferon-induced transmembrane protein VitD-bind_III PF09164.10 KKK26148.1 - 0.12 12.3 0.1 0.29 11.1 0.1 1.6 1 0 0 1 1 1 0 Vitamin D binding protein, domain III T2SSF PF00482.23 KKK26148.1 - 0.15 12.0 4.9 1.6 8.7 0.4 2.4 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F Syntaxin-6_N PF09177.11 KKK26148.1 - 0.17 12.5 8.8 4.2 8.0 1.0 3.4 1 1 2 3 3 3 0 Syntaxin 6, N-terminal MCU PF04678.13 KKK26148.1 - 0.37 10.9 8.2 0.14 12.3 0.9 2.3 1 1 1 2 2 2 0 Mitochondrial calcium uniporter Synaptobrevin PF00957.21 KKK26148.1 - 0.48 10.2 3.5 0.23 11.3 0.5 2.1 2 0 0 2 2 2 0 Synaptobrevin TetR_C_15 PF17918.1 KKK26148.1 - 0.6 10.9 3.7 16 6.3 0.2 2.4 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain SKA1 PF07160.12 KKK26148.1 - 0.8 9.5 9.2 0.45 10.3 1.3 2.4 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 1 GP41 PF00517.17 KKK26148.1 - 1.8 8.4 6.9 1.2 9.0 3.7 2.4 2 1 0 2 2 2 0 Retroviral envelope protein CwsA PF10814.8 KKK26148.1 - 2.3 8.4 8.6 5.1 7.3 7.1 2.3 1 1 1 2 2 2 0 Cell wall synthesis protein CwsA Mobilization_B PF17511.2 KKK26148.1 - 3.1 8.2 12.7 0.17 12.3 1.9 3.0 1 1 2 3 3 3 0 Mobilization protein B AKNA PF12443.8 KKK26148.1 - 3.3 8.4 7.8 1.2 9.8 0.3 3.3 1 1 1 3 3 3 0 AT-hook-containing transcription factor DUF1664 PF07889.12 KKK26148.1 - 6.3 6.9 8.8 4.9 7.2 1.5 3.0 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) BolA PF01722.18 KKK26149.1 - 1.5e-29 102.0 2.0 1.9e-29 101.8 2.0 1.1 1 0 0 1 1 1 1 BolA-like protein # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Aspergillus_ochraceoroseus-ASM98666v1/GCA_000986665.1_ASM98666v1_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Aspergillus_ochraceoroseus-ASM98666v1/GCA_000986665.1_ASM98666v1_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Aspergillus_ochraceoroseus-ASM98666v1/GCA_000986665.1_ASM98666v1_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Aspergillus_ochraceoroseus-ASM98666v1/GCA_000986665.1_ASM98666v1_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Sun Mar 24 14:03:52 2019 # [ok]